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Search of human proteins with 66529407
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|66529407 tensin [Homo sapiens]
(1735 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|66529407 tensin [Homo sapiens] 3521 0.0
gi|65288071 tensin 3 [Homo sapiens] 689 0.0
gi|38787957 tensin like C1 domain containing phosphatase isoform... 499 e-141
gi|38787941 tensin like C1 domain containing phosphatase isoform... 499 e-141
gi|38787970 tensin like C1 domain containing phosphatase isoform... 498 e-140
gi|157738639 tensin 4 [Homo sapiens] 317 5e-86
gi|157384971 cyclin G associated kinase [Homo sapiens] 145 3e-34
gi|73765544 phosphatase and tensin homolog [Homo sapiens] 142 3e-33
gi|40549435 transmembrane phosphatase with tensin homology isofo... 124 8e-28
gi|40549433 transmembrane phosphatase with tensin homology isofo... 124 8e-28
gi|109689707 transmembrane phosphatase with tensin homology isof... 124 8e-28
gi|7662146 DnaJ (Hsp40) homolog, subfamily C, member 6 [Homo sap... 120 2e-26
gi|213972593 TPTE and PTEN homologous inositol lipid phosphatase... 114 6e-25
gi|213972591 TPTE and PTEN homologous inositol lipid phosphatase... 114 6e-25
gi|213972589 TPTE and PTEN homologous inositol lipid phosphatase... 114 6e-25
gi|163965366 nascent polypeptide-associated complex alpha subuni... 99 3e-20
gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 87 1e-16
gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 87 1e-16
gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapi... 86 4e-16
gi|18079216 CASK interacting protein 1 [Homo sapiens] 81 1e-14
gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo ... 76 3e-13
gi|112734870 hypothetical protein LOC57648 [Homo sapiens] 75 7e-13
gi|239743293 PREDICTED: mucin 12 [Homo sapiens] 74 9e-13
gi|55750053 atrophin-1 [Homo sapiens] 71 1e-11
gi|55750041 atrophin-1 [Homo sapiens] 71 1e-11
gi|239754668 PREDICTED: mucin 12 [Homo sapiens] 70 2e-11
gi|115298682 HBxAg transactivated protein 2 [Homo sapiens] 70 2e-11
gi|189181724 proteoglycan 4 isoform D [Homo sapiens] 69 5e-11
gi|189181722 proteoglycan 4 isoform C [Homo sapiens] 69 5e-11
gi|189181720 proteoglycan 4 isoform B [Homo sapiens] 69 5e-11
>gi|66529407 tensin [Homo sapiens]
Length = 1735
Score = 3521 bits (9130), Expect = 0.0
Identities = 1735/1735 (100%), Positives = 1735/1735 (100%)
Query: 1 MSVSRTMEDSCELDLVYVTERIIAVSFPSTANEENFRSNLREVAQMLKSKHGGNYLLFNL 60
MSVSRTMEDSCELDLVYVTERIIAVSFPSTANEENFRSNLREVAQMLKSKHGGNYLLFNL
Sbjct: 1 MSVSRTMEDSCELDLVYVTERIIAVSFPSTANEENFRSNLREVAQMLKSKHGGNYLLFNL 60
Query: 61 SERRPDITKLHAKVLEFGWPDLHTPALEKICSICKAMDTWLNADPHNVVVLHNKGNRGRI 120
SERRPDITKLHAKVLEFGWPDLHTPALEKICSICKAMDTWLNADPHNVVVLHNKGNRGRI
Sbjct: 61 SERRPDITKLHAKVLEFGWPDLHTPALEKICSICKAMDTWLNADPHNVVVLHNKGNRGRI 120
Query: 121 GVVIAAYMHYSNISASADQALDRFAMKRFYEDKIVPIGQPSQRRYVHYFSGLLSGSIKMN 180
GVVIAAYMHYSNISASADQALDRFAMKRFYEDKIVPIGQPSQRRYVHYFSGLLSGSIKMN
Sbjct: 121 GVVIAAYMHYSNISASADQALDRFAMKRFYEDKIVPIGQPSQRRYVHYFSGLLSGSIKMN 180
Query: 181 NKPLFLHHVIMHGIPNFESKGGCRPFLRIYQAMQPVYTSGIYNIPGDSQTSVCITIEPGL 240
NKPLFLHHVIMHGIPNFESKGGCRPFLRIYQAMQPVYTSGIYNIPGDSQTSVCITIEPGL
Sbjct: 181 NKPLFLHHVIMHGIPNFESKGGCRPFLRIYQAMQPVYTSGIYNIPGDSQTSVCITIEPGL 240
Query: 241 LLKGDILLKCYHKKFRSPARDVIFRVQFHTCAIHDLGVVFGKEDLDDAFKDDRFPEYGKV 300
LLKGDILLKCYHKKFRSPARDVIFRVQFHTCAIHDLGVVFGKEDLDDAFKDDRFPEYGKV
Sbjct: 241 LLKGDILLKCYHKKFRSPARDVIFRVQFHTCAIHDLGVVFGKEDLDDAFKDDRFPEYGKV 300
Query: 301 EFVFSYGPEKIQGMEHLENGPSVSVDYNTSDPLIRWDSYDNFSGHRDDGMEEVVGHTQGP 360
EFVFSYGPEKIQGMEHLENGPSVSVDYNTSDPLIRWDSYDNFSGHRDDGMEEVVGHTQGP
Sbjct: 301 EFVFSYGPEKIQGMEHLENGPSVSVDYNTSDPLIRWDSYDNFSGHRDDGMEEVVGHTQGP 360
Query: 361 LDGSLYAKVKKKDSLHGSTGAVNATRPTLSATPNHVEHTLSVSSDSGNSTASTKTDKTDE 420
LDGSLYAKVKKKDSLHGSTGAVNATRPTLSATPNHVEHTLSVSSDSGNSTASTKTDKTDE
Sbjct: 361 LDGSLYAKVKKKDSLHGSTGAVNATRPTLSATPNHVEHTLSVSSDSGNSTASTKTDKTDE 420
Query: 421 PVPGASSATAALSPQEKRELDRLLSGFGLEREKQGAMYHTQHLRSRPAGGSAVPSSGRHV 480
PVPGASSATAALSPQEKRELDRLLSGFGLEREKQGAMYHTQHLRSRPAGGSAVPSSGRHV
Sbjct: 421 PVPGASSATAALSPQEKRELDRLLSGFGLEREKQGAMYHTQHLRSRPAGGSAVPSSGRHV 480
Query: 481 VPAQVHVNGGALASERETDILDDELPNQDGHSAGSMGTLSSLDGVTNTSEGGYPEALSPL 540
VPAQVHVNGGALASERETDILDDELPNQDGHSAGSMGTLSSLDGVTNTSEGGYPEALSPL
Sbjct: 481 VPAQVHVNGGALASERETDILDDELPNQDGHSAGSMGTLSSLDGVTNTSEGGYPEALSPL 540
Query: 541 TNGLDKSYPMEPMVNGGGYPYESASRAGPAHAGHTAPMRPSYSAQEGLAGYQREGPHPAW 600
TNGLDKSYPMEPMVNGGGYPYESASRAGPAHAGHTAPMRPSYSAQEGLAGYQREGPHPAW
Sbjct: 541 TNGLDKSYPMEPMVNGGGYPYESASRAGPAHAGHTAPMRPSYSAQEGLAGYQREGPHPAW 600
Query: 601 PQPVTTSHYAHDPSGMFRSQSFSEAEPQLPPAPVRGGSSREAVQRGLNSWQQQQQQQQQP 660
PQPVTTSHYAHDPSGMFRSQSFSEAEPQLPPAPVRGGSSREAVQRGLNSWQQQQQQQQQP
Sbjct: 601 PQPVTTSHYAHDPSGMFRSQSFSEAEPQLPPAPVRGGSSREAVQRGLNSWQQQQQQQQQP 660
Query: 661 RPPPRQQERAHLESLVASRPSPQPLAETPIPSLPEFPRAASQQEIEQSIETLNMLMLDLE 720
RPPPRQQERAHLESLVASRPSPQPLAETPIPSLPEFPRAASQQEIEQSIETLNMLMLDLE
Sbjct: 661 RPPPRQQERAHLESLVASRPSPQPLAETPIPSLPEFPRAASQQEIEQSIETLNMLMLDLE 720
Query: 721 PASAAAPLHKSQSVPGAWPGASPLSSQPLSGSSRQSHPLTQSRSGYIPSGHSLGTPEPAP 780
PASAAAPLHKSQSVPGAWPGASPLSSQPLSGSSRQSHPLTQSRSGYIPSGHSLGTPEPAP
Sbjct: 721 PASAAAPLHKSQSVPGAWPGASPLSSQPLSGSSRQSHPLTQSRSGYIPSGHSLGTPEPAP 780
Query: 781 RASLESVPPGRSYSPYDYQPCLAGPNQDFHSKSPASSSLPAFLPTTHSPPGPQQPPASLP 840
RASLESVPPGRSYSPYDYQPCLAGPNQDFHSKSPASSSLPAFLPTTHSPPGPQQPPASLP
Sbjct: 781 RASLESVPPGRSYSPYDYQPCLAGPNQDFHSKSPASSSLPAFLPTTHSPPGPQQPPASLP 840
Query: 841 GLTAQPLLSPKEATSDPSRTPEEEPLNLEGLVAHRVAGVQAREKQPAEPPAPLRRRAASD 900
GLTAQPLLSPKEATSDPSRTPEEEPLNLEGLVAHRVAGVQAREKQPAEPPAPLRRRAASD
Sbjct: 841 GLTAQPLLSPKEATSDPSRTPEEEPLNLEGLVAHRVAGVQAREKQPAEPPAPLRRRAASD 900
Query: 901 GQYENQSPEATSPRSPGVRSPVQCVSPELALTIALNPGGRPKEPHLHSYKEAFEEMEGTS 960
GQYENQSPEATSPRSPGVRSPVQCVSPELALTIALNPGGRPKEPHLHSYKEAFEEMEGTS
Sbjct: 901 GQYENQSPEATSPRSPGVRSPVQCVSPELALTIALNPGGRPKEPHLHSYKEAFEEMEGTS 960
Query: 961 PSSPPPSGVRSPPGLAKTPLSALGLKPHNPADILLHPTGVTRRRIQPEEDEGKVVVRLSE 1020
PSSPPPSGVRSPPGLAKTPLSALGLKPHNPADILLHPTGVTRRRIQPEEDEGKVVVRLSE
Sbjct: 961 PSSPPPSGVRSPPGLAKTPLSALGLKPHNPADILLHPTGVTRRRIQPEEDEGKVVVRLSE 1020
Query: 1021 EPRSYVESVARTAVAGPRAQDSEPKSFSAPATQAYGHEIPLRNGTLGGSFVSPSPLSTSS 1080
EPRSYVESVARTAVAGPRAQDSEPKSFSAPATQAYGHEIPLRNGTLGGSFVSPSPLSTSS
Sbjct: 1021 EPRSYVESVARTAVAGPRAQDSEPKSFSAPATQAYGHEIPLRNGTLGGSFVSPSPLSTSS 1080
Query: 1081 PILSADSTSVGSFPSGESSDQGPRTPTQPLLESGFRSGSLGQPSPSAQRNYQSSSPLPTV 1140
PILSADSTSVGSFPSGESSDQGPRTPTQPLLESGFRSGSLGQPSPSAQRNYQSSSPLPTV
Sbjct: 1081 PILSADSTSVGSFPSGESSDQGPRTPTQPLLESGFRSGSLGQPSPSAQRNYQSSSPLPTV 1140
Query: 1141 GSSYSSPDYSLQHFSSSPESQARAQFSVAGVHTVPGSPQARHRTVGTNTPPSPGFGWRAI 1200
GSSYSSPDYSLQHFSSSPESQARAQFSVAGVHTVPGSPQARHRTVGTNTPPSPGFGWRAI
Sbjct: 1141 GSSYSSPDYSLQHFSSSPESQARAQFSVAGVHTVPGSPQARHRTVGTNTPPSPGFGWRAI 1200
Query: 1201 NPSMAAPSSPSLSHHQMMGPPGTGFHGSTVSSPQSSAATTPGSPSLCRHPAGVYQVSGLH 1260
NPSMAAPSSPSLSHHQMMGPPGTGFHGSTVSSPQSSAATTPGSPSLCRHPAGVYQVSGLH
Sbjct: 1201 NPSMAAPSSPSLSHHQMMGPPGTGFHGSTVSSPQSSAATTPGSPSLCRHPAGVYQVSGLH 1260
Query: 1261 NKVATTPGSPSLGRHPGAHQGNLASGLHSNAIASPGSPSLGRHLGGSGSVVPGSPCLDRH 1320
NKVATTPGSPSLGRHPGAHQGNLASGLHSNAIASPGSPSLGRHLGGSGSVVPGSPCLDRH
Sbjct: 1261 NKVATTPGSPSLGRHPGAHQGNLASGLHSNAIASPGSPSLGRHLGGSGSVVPGSPCLDRH 1320
Query: 1321 VAYGGYSTPEDRRPTLSRQSSASGYQAPSTPSFPVSPAYYPGLSSPATSPSPDSAAFRQG 1380
VAYGGYSTPEDRRPTLSRQSSASGYQAPSTPSFPVSPAYYPGLSSPATSPSPDSAAFRQG
Sbjct: 1321 VAYGGYSTPEDRRPTLSRQSSASGYQAPSTPSFPVSPAYYPGLSSPATSPSPDSAAFRQG 1380
Query: 1381 SPTPALPEKRRMSVGDRAGSLPNYATINGKVSSPVASGMSSPSGGSTVSFSHTLPDFSKY 1440
SPTPALPEKRRMSVGDRAGSLPNYATINGKVSSPVASGMSSPSGGSTVSFSHTLPDFSKY
Sbjct: 1381 SPTPALPEKRRMSVGDRAGSLPNYATINGKVSSPVASGMSSPSGGSTVSFSHTLPDFSKY 1440
Query: 1441 SMPDNSPETRAKVKFVQDTSKYWYKPEISREQAIALLKDQEPGAFIIRDSHSFRGAYGLA 1500
SMPDNSPETRAKVKFVQDTSKYWYKPEISREQAIALLKDQEPGAFIIRDSHSFRGAYGLA
Sbjct: 1441 SMPDNSPETRAKVKFVQDTSKYWYKPEISREQAIALLKDQEPGAFIIRDSHSFRGAYGLA 1500
Query: 1501 MKVSSPPPTIMQQNKKGDMTHELVRHFLIETGPRGVKLKGCPNEPNFGSLSALVYQHSII 1560
MKVSSPPPTIMQQNKKGDMTHELVRHFLIETGPRGVKLKGCPNEPNFGSLSALVYQHSII
Sbjct: 1501 MKVSSPPPTIMQQNKKGDMTHELVRHFLIETGPRGVKLKGCPNEPNFGSLSALVYQHSII 1560
Query: 1561 PLALPCKLVIPNRDPTDESKDSSGPANSTADLLKQGAACNVLFVNSVDMESLTGPQAISK 1620
PLALPCKLVIPNRDPTDESKDSSGPANSTADLLKQGAACNVLFVNSVDMESLTGPQAISK
Sbjct: 1561 PLALPCKLVIPNRDPTDESKDSSGPANSTADLLKQGAACNVLFVNSVDMESLTGPQAISK 1620
Query: 1621 ATSETLAADPTPAATIVHFKVSAQGITLTDNQRKLFFRRHYPLNTVTFCDLDPQERKWMK 1680
ATSETLAADPTPAATIVHFKVSAQGITLTDNQRKLFFRRHYPLNTVTFCDLDPQERKWMK
Sbjct: 1621 ATSETLAADPTPAATIVHFKVSAQGITLTDNQRKLFFRRHYPLNTVTFCDLDPQERKWMK 1680
Query: 1681 TEGGAPAKLFGFVARKQGSTTDNACHLFAELDPNQPASAIVNFVSKVMLNAGQKR 1735
TEGGAPAKLFGFVARKQGSTTDNACHLFAELDPNQPASAIVNFVSKVMLNAGQKR
Sbjct: 1681 TEGGAPAKLFGFVARKQGSTTDNACHLFAELDPNQPASAIVNFVSKVMLNAGQKR 1735
>gi|65288071 tensin 3 [Homo sapiens]
Length = 1445
Score = 689 bits (1777), Expect = 0.0
Identities = 494/1251 (39%), Positives = 647/1251 (51%), Gaps = 200/1251 (15%)
Query: 7 MEDSCELDLVYVTERIIAVSFPSTANEENFRSNLREVAQMLKSKHGGNYLLFNLSERRPD 66
ME+ LDL Y+TERIIAVSFP+ +EE++ NL+EV +MLKSKHG NYL+ NLSE+R D
Sbjct: 1 MEEGHGLDLTYITERIIAVSFPAGCSEESYLHNLQEVTRMLKSKHGDNYLVLNLSEKRYD 60
Query: 67 ITKLHAKVLEFGWPDLHTPALEKICSICKAMDTWLNADPHNVVVLHNKGNRGRIGVVIAA 126
+TKL+ K+++ GWP+LH P L+K+C+ICKA ++WLN++ +VVV+H +G +GRIGVVI++
Sbjct: 61 LTKLNPKIMDVGWPELHAPPLDKMCTICKAQESWLNSNLQHVVVIHCRGGKGRIGVVISS 120
Query: 127 YMHYSNISASADQALDRFAMKRFYEDKIVPIGQPSQRRYVHYFSGLLSGSIKMNNKPLFL 186
YMH++N+SASADQALDRFAMK+FY+DK+ + QPSQ+RYV + SGLLSGS+KMN PLFL
Sbjct: 121 YMHFTNVSASADQALDRFAMKKFYDDKVSALMQPSQKRYVQFLSGLLSGSVKMNASPLFL 180
Query: 187 HHVIMHGIPNFESKGGCRPFLRIYQAMQPVYTSGIYNIPGDSQTSVCITIEPGLLLKGDI 246
H VI+HG PNF++ G CRPFL++YQAMQPVYTSGIYN+ ++ + +CI IEP LLKGD+
Sbjct: 181 HFVILHGTPNFDTGGVCRPFLKLYQAMQPVYTSGIYNVGPENPSRICIVIEPAQLLKGDV 240
Query: 247 LLKCYHKKFRSPARDVIFRVQFHTCAIHDLGVVFGKEDLDDAFKDDRFPEYGKVEFVFSY 306
++KCYHKK+RS RDVIFR+QFHT A+ G+VFGKEDLD+A KDDRFP+YGKVE VFS
Sbjct: 241 MVKCYHKKYRSATRDVIFRLQFHTGAVQGYGLVFGKEDLDNASKDDRFPDYGKVELVFSA 300
Query: 307 GPEKIQGMEHLENGPSVSVDYNTSDPLIRWDSYDNFSGHRDDGMEEVVGHTQGPLDGSLY 366
PEKIQG EHL N V VDYNT+DPLIRWDSY+N S DG EV+ HTQGP+DGSLY
Sbjct: 301 TPEKIQGSEHLYNDHGVIVDYNTTDPLIRWDSYENLSA---DG--EVL-HTQGPVDGSLY 354
Query: 367 AKVKKKDS----LHGSTGAVNATRPTLSATPNHVEHTLSVSSDSGNSTASTKTDKTDEPV 422
AKV+KK S + G A+ AT +P+H +HTLSVSSDSG+STAS +TDKT+E +
Sbjct: 355 AKVRKKSSSDPGIPGGPQAIPATN-----SPDHSDHTLSVSSDSGHSTASARTDKTEERL 409
Query: 423 PGASSATAALSPQEKRELDRLLSGFGLEREKQGAMYHTQHLRSRPAGGSAVPSSGRHVVP 482
A LS QEK ELD+LLSGFGLE + ++ RS+ +G RHVVP
Sbjct: 410 --APGTRRGLSAQEKAELDQLLSGFGLE-DPGSSLKEMTDARSKYSG-------TRHVVP 459
Query: 483 AQVHVNGGALASERETDILDDELPNQDGHSAGSMGTLSSLDGVTNTSEGGY----PEALS 538
AQVHVNG A +RETDILDDE+P+ D HS S+GTLSS +G + G + S
Sbjct: 460 AQVHVNGDAALKDRETDILDDEMPHHDLHSVDSLGTLSSSEGPQSAHLGPFTCHKSSQNS 519
Query: 539 PLTNGLDKSYPMEPMVN-------GGGYPYESASRAGPAHAGHTAPM--RPSYSAQEGLA 589
L++G + +P G PYE G P+ +PS SAQ
Sbjct: 520 LLSDGFGSNVGEDPQGTLVPDLGLGMDGPYERERTFGSREPKQPQPLLRKPSVSAQMQAY 579
Query: 590 GYQREGPHPAW---PQPVTTSHYAHDPSGMFR--------SQSFSEAEPQLPPAPVRGGS 638
G Q W Q V Y+ P G R + +A+P++P P RG S
Sbjct: 580 G-QSSYSTQTWVRQQQMVVAHQYSFAPDGEARLVSRCPADNPGLVQAQPRVPLTPTRGTS 638
Query: 639 SREAVQRGLNSWQQQQQQQQQPRPPPRQQERAHLESLVASRPSPQPLAETPIPSLPEFPR 698
SR AVQRG+ S QQ P P + + + L+ P P P
Sbjct: 639 SRVAVQRGVGSGPHPPDTQQ---PSPSKAFKPRFPGDQVVNGAGPELSTGPSPGSPTL-- 693
Query: 699 AASQQEIEQSIETLNMLMLDLEPASAAAPLHKS------------QSVPGAWPGASPL-- 744
+I+QSIE LN L+L+L+P P H + SV G +S L
Sbjct: 694 -----DIDQSIEQLNRLILELDPTFEPIPTHMNALGSQANGSVSPDSVGGGLRASSRLPD 748
Query: 745 ---------------SSQPLSGSSRQ----------SHPLTQSRSGYIPSGHSLG---TP 776
+ QPL G R+ L S+ + +G P
Sbjct: 749 TGEGPSRATGRQGSSAEQPLGGRLRKLSLGQYDNDAGGQLPFSKCAWGKAGVDYAPNLPP 808
Query: 777 EPAPRASLESVPPGRSYSPYDYQPCLAGPNQDFHSKSPASSSLPAFLPTTHSPPGPQQPP 836
P+P E++ PG Y L + S + S PAF P P+ P
Sbjct: 809 FPSPADVKETMTPG-------YPQDLDIIDGRILSSKESMCSTPAF------PVSPETPY 855
Query: 837 ASLPGLTAQPLLSPKEATSDPSRTPE--EEPLNLEGLVAHRVAGVQAREKQPAEPPAPLR 894
L P P+ S P+ + EP + + H V + P P + +
Sbjct: 856 VK-TALRHPPFSPPEPPLSSPASQHKGGREPRSCPETLTHAV----GMSESPIGPKSTML 910
Query: 895 RRAASDG---QYENQSPEATSPRSPGVR------SPVQCVSPELALTIALNPGGRPKEPH 945
R AS Q S S PG R + Q V ++L GRP
Sbjct: 911 RADASSTPSFQQAFASSCTISSNGPGQRRESSSSAERQWVESSPKPMVSLLGSGRPTGSP 970
Query: 946 LHSYKEAFEEMEGTSPSSP-----PPSGVRSP-----PGLAKTPLSALGLKPHNPADILL 995
L + E GT SP PPS +++P LA+ P S L P + L
Sbjct: 971 LSA------EFSGTRKDSPVLSCFPPSELQAPFHSHELSLAEPPDS---LAPPSSQAFLG 1021
Query: 996 HPTGVTRRRIQPEEDEGKVVVRLSEEPRSYVESVARTAVAGPRAQDSEPKSFSAPATQAY 1055
T + PEED G ++ + S S+ TA A D
Sbjct: 1022 FGTAPVGSGLPPEEDLGALLA--NSHGASPTPSIPLTATG---AAD-------------- 1062
Query: 1056 GHEIPLRNGTLGGSF--VSPSPLSTSSPILSADSTSVGSFPSGESSDQGPRTPTQPLLES 1113
NG L +F V+P S SP L QG P QP L
Sbjct: 1063 -------NGFLSHNFLTVAPGHSSHHSPGLQG---------------QGVTLPGQPPLPE 1100
Query: 1114 GFRSG----SLGQPSPSAQRNYQSSSPLPTVGSSYSS--PDYSLQHFSSSP 1158
R+ SLG SPS+ + S T+ + + PD+S ++SP
Sbjct: 1101 KKRASEGDRSLGSVSPSSS-GFSSPHSGSTISIPFPNVLPDFSKASEAASP 1150
Score = 464 bits (1193), Expect = e-130
Identities = 301/664 (45%), Positives = 376/664 (56%), Gaps = 65/664 (9%)
Query: 1086 DSTSVGSFPSGESSDQGPRTPTQPLLESGFRSGSLGQPSPSAQRNYQSSSPLPTVGSSYS 1145
D + S S S+ P +P P +++ R P P S + G
Sbjct: 831 DGRILSSKESMCSTPAFPVSPETPYVKTALRHPPFSPPEPPLS----SPASQHKGGREPR 886
Query: 1146 SPDYSLQHFSSSPESQARAQFSVAGVHTVPGSPQARHRTVGTNTPPSPGFGWRAINPSMA 1205
S +L H ES + ++ +P + + T S G G R + S A
Sbjct: 887 SCPETLTHAVGMSESPIGPKSTMLRADA-SSTPSFQQAFASSCTISSNGPGQRRESSSSA 945
Query: 1206 APSSPSLSHHQMMGPPGTGFHGSTVSSPQSS--AATTPGSPSLCRHPAGVYQVSGLHNKV 1263
S M+ G+G SP S+ + T SP L P Q +++
Sbjct: 946 ERQWVESSPKPMVSLLGSG---RPTGSPLSAEFSGTRKDSPVLSCFPPSELQAPFHSHEL 1002
Query: 1264 ATTPGSPSLGRHPGAHQGNLASGLHSNAIASPGSPSLGRHLGGS--GSVVPGSPCLDRHV 1321
+ SL P + Q L G P LG L S S P P
Sbjct: 1003 SLAEPPDSLA--PPSSQAFLGFGTAPVGSGLPPEEDLGALLANSHGASPTPSIPLTATGA 1060
Query: 1322 AYGGYSTPEDRRPTLSRQSSASGYQAPSTPSFPVSPAYYPGLSSPATSPSPDSAAFRQGS 1381
A G+ + + + A G+ + +P PG
Sbjct: 1061 ADNGFLSH-------NFLTVAPGHSSHHSPGLQGQGVTLPG------------------- 1094
Query: 1382 PTPALPEKRRMSVGDRA-GSLPNYATINGKVSSPVASGMSSPSGGSTVS--FSHTLPDFS 1438
P LPEK+R S GDR+ GS+ SP +SG SSP GST+S F + LPDFS
Sbjct: 1095 -QPPLPEKKRASEGDRSLGSV-----------SPSSSGFSSPHSGSTISIPFPNVLPDFS 1142
Query: 1439 KYS-----MPDNSPETRAKVKFVQDTSKYWYKPEISREQAIALLKDQEPGAFIIRDSHSF 1493
K S +PD+ + VKFVQDTSK+WYK +ISREQAIA+LKD+EPG+FI+RDSHSF
Sbjct: 1143 KASEAASPLPDSPGDKLVIVKFVQDTSKFWYKADISREQAIAMLKDKEPGSFIVRDSHSF 1202
Query: 1494 RGAYGLAMKVSSPPPTIMQQNKK-GDMTHELVRHFLIETGPRGVKLKGCPNEPNFGSLSA 1552
RGAYGLAMKV++PPP+++Q NKK GD+ +ELVRHFLIE P+GV+LKGC NEP FGSL+A
Sbjct: 1203 RGAYGLAMKVATPPPSVLQLNKKAGDLANELVRHFLIECTPKGVRLKGCSNEPYFGSLTA 1262
Query: 1553 LVYQHSIIPLALPCKLVIPNRDPTDESKDSSGP--ANSTADLLKQGAACNVLFVNSVDME 1610
LV QHSI PLALPCKL+IP RDP +E +SS ANS A+LLKQGAACNV ++NSV+ME
Sbjct: 1263 LVCQHSITPLALPCKLLIPERDPLEEIAESSPQTAANSAAELLKQGAACNVWYLNSVEME 1322
Query: 1611 SLTGPQAISKATSETLAADPTPAATIVHFKVSAQGITLTDNQRKLFFRRHYPLNTVTFCD 1670
SLTG QAI KA S TL +P P +T+VHFKVSAQGITLTDNQRKLFFRRHYP+N+V FC
Sbjct: 1323 SLTGHQAIQKALSITLVQEPPPVSTVVHFKVSAQGITLTDNQRKLFFRRHYPVNSVIFCA 1382
Query: 1671 LDPQERKWMKTEGGAPAKLFGFVARKQGSTTDNACHLFAELDPNQPASAIVNFVSKVMLN 1730
LDPQ+RKW+K G +K+FGFVARKQGS TDN CHLFAE DP QPASAIVNFVSKVM+
Sbjct: 1383 LDPQDRKWIK--DGPSSKVFGFVARKQGSATDNVCHLFAEHDPEQPASAIVNFVSKVMIG 1440
Query: 1731 AGQK 1734
+ +K
Sbjct: 1441 SPKK 1444
>gi|38787957 tensin like C1 domain containing phosphatase isoform 2
[Homo sapiens]
Length = 1409
Score = 499 bits (1285), Expect = e-141
Identities = 367/1022 (35%), Positives = 499/1022 (48%), Gaps = 145/1022 (14%)
Query: 2 SVSRTMEDSCELDLVYVTERIIAVSFPSTANEENFRSNLREVAQMLKSKHGGNYLLFNLS 61
S+ ME +LDL YVTERI+A +FP+ +E+ R +LRE+A +L+SKH YLLFNLS
Sbjct: 120 SLDPLMERRWDLDLTYVTERILAAAFPARPDEQRHRGHLRELAHVLQSKHRDKYLLFNLS 179
Query: 62 ERRPDITKLHAKVLEFGWPDLHTPALEKICSICKAMDTWLNADPHNVVVLHNKGNRGRIG 121
E+R D+T+L+ KV +FGWP+LH P L+K+CSICKAM+TWL+ADP +VVVL+ KGN+G++G
Sbjct: 180 EKRHDLTRLNPKVQDFGWPELHAPPLDKLCSICKAMETWLSADPQHVVVLYCKGNKGKLG 239
Query: 122 VVIAAYMHYSNISASADQALDRFAMKRFYEDKIVPIGQPSQRRYVHYFSGLLSGSIKMNN 181
V+++AYMHYS ISA ADQAL M++F EDK+ QPSQRRY+ YFSGLLSGSI+MN+
Sbjct: 240 VIVSAYMHYSKISAGADQALATLTMRKFCEDKVATELQPSQRRYISYFSGLLSGSIRMNS 299
Query: 182 KPLFLHHVIMHGIPNFESKGGCRPFLRIYQAMQPVYTSGIYNIPGDSQTSVCITIEPGLL 241
PLFLH+V++ +P FE G +PFL+IYQ+MQ VYTSG+Y+I G +CI++EP LL
Sbjct: 300 SPLFLHYVLIPMLPAFEPGTGFQPFLKIYQSMQLVYTSGVYHIAGPGPQQLCISLEPALL 359
Query: 242 LKGDILLKCYHKKFRSPARDVIFRVQFHTCAIHDLGVVFGKEDLDDAFKDDRFPEYGKVE 301
LKGD+++ CYHK R R ++FRVQFHTC IH + F K+ LD+A+ D+RFP VE
Sbjct: 360 LKGDVMVTCYHKGGRGTDRTLVFRVQFHTCTIHGPQLTFPKDQLDEAWTDERFPFQASVE 419
Query: 302 FVFSYGPEKIQGMEHLENGPSVSVDYNTSDPLIRWDSYDNFSGHRDDGMEEVVGHTQGPL 361
FVFS PEKI+G N PSVSVDYNT++P +RWDSY+NF+ H +D ++ + HT+GPL
Sbjct: 420 FVFSSSPEKIKGSTP-RNDPSVSVDYNTTEPAVRWDSYENFNQHHEDSVDGSLTHTRGPL 478
Query: 362 DGSLYAKVKKKDSLHGSTGAVNATRPTLSATPNHVEHTLSVSSDSGNSTASTKTDKTDEP 421
DGS YA+V++ T P S P LSVSSDSG+S ST T +
Sbjct: 479 DGSPYAQVQRPP---------RQTPPAPSPEP-PPPPMLSVSSDSGHS--STLTTEPAAE 526
Query: 422 VPGASSATAALSPQEKRELDRLLSGFGLEREKQGAMYHTQHL--RSRPAGGSAV------ 473
PG TAA E++ELDRLL G G+ +GA T L +P G
Sbjct: 527 SPGRPPPTAA----ERQELDRLLGGCGVASGGRGAGRETAILDDEEQPTVGGGPHLGVYP 582
Query: 474 ---PSSGRHVVPAQVH------VNGGALASERETDILDDELPNQDGHSAG-SMGTLSSLD 523
P RH Q + NGG E + +G G + ++
Sbjct: 583 GHRPGLSRHCSCRQGYREPCGVPNGGYYRPEGTLERRRLAYGGYEGSPQGYAEASMEKRR 642
Query: 524 GVTNTSEGGY---PEALSPLTN------------------GLDKSYPM------------ 550
+ SEG Y PE P T GL YP
Sbjct: 643 LCRSLSEGLYPYPPEMGKPATGDFGYRAPGYREVVILEDPGLPALYPCPACEEKLALPTA 702
Query: 551 ------------EPMVNGGGYPYESASRAG-------PAHAGHTAPM------RPSYSAQ 585
E + G P R G PA H APM +P + +
Sbjct: 703 ALYGLRLEREAGEGWASEAGKPLLHPVRPGHPLPLLLPACGHHHAPMPDYSCLKPPKAGE 762
Query: 586 EGLAGYQ----REG--PHPAWPQPVTTSHYAHDPS-----GMFRSQSFSEAEPQLPPAPV 634
EG G EG HP +P VT S+ PS G S E + P+P
Sbjct: 763 EGHEGCSYTMCPEGRYGHPGYPALVTYSYGGAVPSYCPAYGRVPHSCGSPGEGRGYPSPG 822
Query: 635 RGGSSREAVQRGLNSWQQQQQQQQQ---PRPPPRQQERAHLESL--VASRPSPQPLAETP 689
++ G + Q ++ + R HL S +AS S +P++
Sbjct: 823 AHSPRAGSISPGSPPYPQSRKLSYEIPTEEGGDRYPLPGHLASAGPLASAESLEPVSWRE 882
Query: 690 IPS----LPEFPRAASQQEIEQSIETLNMLMLDLEPASAAAPLHKSQSVPGAWPGASPLS 745
PS LP PR A E + + PLH S V G +
Sbjct: 883 GPSGHSTLPRSPRDAP-------------CSASSELSGPSTPLHTSSPVQGKESTRRQDT 929
Query: 746 SQPLSGSSRQSH------PLTQSRSGYIPSGHSLGTPEPAPRASLESVPPGRSYSPYDYQ 799
P S +++ P++Q+ +G P S PEP + + P S S + +
Sbjct: 930 RSPTSAPTQRLSPGEALPPVSQAGTGKAPELPSGSGPEPLAPSPVSPTFPPSSPSDWPQE 989
Query: 800 PCLAGPNQDFHSKSPASSSLPAFLPTTHSP-PGPQQPPASLPGLTAQPLLSPKEATSDPS 858
G + +SP ++LP H+P GP+ PP S G P+ S
Sbjct: 990 RSPGGHSDGASPRSPVPTTLPGL---RHAPWQGPRGPPDSPDGSPLTPVPSQMPWLVASP 1046
Query: 859 RTPEEEPLNLEGLVA-HRVAGVQAREKQPAEPPAPLRRRAASDGQYENQ-SPEATSPRSP 916
P+ P L A + G+ ++PP P +R GQ PE S +
Sbjct: 1047 EPPQSSPTPAFPLAASYDTNGL-------SQPPLPEKRHLPGPGQQPGPWGPEQASSPAR 1099
Query: 917 GV 918
G+
Sbjct: 1100 GI 1101
Score = 409 bits (1052), Expect = e-114
Identities = 269/636 (42%), Positives = 365/636 (57%), Gaps = 69/636 (10%)
Query: 1116 RSGSLGQPSPSAQRNYQSSSPLPTV--GSSYSSPDYSLQHFSSSPESQARAQFSVAGVHT 1173
R+GS+ SP ++ + S +PT G Y P + S+ P + A + V+
Sbjct: 827 RAGSISPGSPPYPQSRKLSYEIPTEEGGDRYPLPGHLA---SAGPLASAESLEPVSWREG 883
Query: 1174 VPGSPQARHRTVGTNTPPSPGFGWRAINPSMAAPSSPSLSHHQMMGPPGTGFHGSTVSSP 1233
G H T+ P SP + + ++ PS+P + + G T + +
Sbjct: 884 PSG-----HSTL----PRSPRDAPCSASSELSGPSTPLHTSSPVQGKESTRRQDTRSPTS 934
Query: 1234 QSSAATTPGSPSLCRHPAGVYQVSGLHN-----KVATTPGSPSLG-RHPGAHQGNLASGL 1287
+ +PG AG + L + +A +P SP+ P + G
Sbjct: 935 APTQRLSPGEALPPVSQAGTGKAPELPSGSGPEPLAPSPVSPTFPPSSPSDWPQERSPGG 994
Query: 1288 HSNAIASPGSPSLGRHLGGSGSVVPGSPCLDRHVAYGGYSTPEDRRPTLSRQSSASGYQA 1347
HS+ ASP SP + +PG RH + G P D S G +
Sbjct: 995 HSDG-ASPRSPV--------PTTLPGL----RHAPWQGPRGPPD---------SPDG--S 1030
Query: 1348 PSTPSFPVSPAYYPGLSSPATSPSPDSAAFRQGSPTPALPEKRRMSV-GDRAGSLPNYAT 1406
P TP P+ P L SP P Q SPTPA P G LP
Sbjct: 1031 PLTPV----PSQMPWL---VASPEPP-----QSSPTPAFPLAASYDTNGLSQPPLPEKRH 1078
Query: 1407 INGKVSSPVASG---MSSPSGGST--VSFSHTLPDFSKYSMPDNSPETRAKVKFVQDTSK 1461
+ G P G SSP+ G + V+F+ L D + + E+++ VKFVQDTSK
Sbjct: 1079 LPGPGQQPGPWGPEQASSPARGISHHVTFAPLLSDNVPQTPEPPTQESQSNVKFVQDTSK 1138
Query: 1462 YWYKPEISREQAIALLKDQEPGAFIIRDSHSFRGAYGLAMKVSSPPPTIMQQNKKGDMTH 1521
+WYKP +SR+QAIALLKD++PGAF+IRDSHSF+GAYGLA+KV++PPP+ Q KGD
Sbjct: 1139 FWYKPHLSRDQAIALLKDKDPGAFLIRDSHSFQGAYGLALKVATPPPSA--QPWKGDPVE 1196
Query: 1522 ELVRHFLIETGPRGVKLKGCPNEPNFGSLSALVYQHSIIPLALPCKLVIPNRDPTDESKD 1581
+LVRHFLIETGP+GVK+KGCP+EP FGSLSALV QHSI P++LPC L IP++DP +E+ +
Sbjct: 1197 QLVRHFLIETGPKGVKIKGCPSEPYFGSLSALVSQHSISPISLPCCLRIPSKDPLEETPE 1256
Query: 1582 SSGPAN--STADLLKQGAACNVLFVNSVDMESLTGPQAISKATSETLAADPTPAATIVHF 1639
+ P N + ADLL+QGAAC+VL++ SV+ ESLTGPQA+++A+S L+ P P +VHF
Sbjct: 1257 APVPTNMSTAADLLRQGAACSVLYLTSVETESLTGPQAVARASSAALSCSPRPTPAVVHF 1316
Query: 1640 KVSAQGITLTDNQRKLFFRRHYPLNTVTFCDLDPQERKWMKTEGGAPAKLFGFVARKQGS 1699
KVSAQGITLTDNQRKLFFRRHYP+N++TF DPQ+R+W + G +K+FGFVA+K GS
Sbjct: 1317 KVSAQGITLTDNQRKLFFRRHYPVNSITFSSTDPQDRRWTNPD-GTTSKIFGFVAKKPGS 1375
Query: 1700 TTDNACHLFAELDPNQPASAIVNFVSKVMLNAGQKR 1735
+N CHLFAELDP+QPA AIV F++KV+L GQ++
Sbjct: 1376 PWENVCHLFAELDPDQPAGAIVTFITKVLL--GQRK 1409
Score = 53.1 bits (126), Expect = 2e-06
Identities = 159/679 (23%), Positives = 218/679 (32%), Gaps = 144/679 (21%)
Query: 637 GSSREAVQRGLNSWQQQQQQQQQPRPPPRQQERAHLESLVASRPSPQPLAETPIPSLPEF 696
GS VQR +Q P PPP +S +S + +P AE+P P
Sbjct: 480 GSPYAQVQRP----PRQTPPAPSPEPPPPPMLSVSSDSGHSSTLTTEPAAESP--GRPP- 532
Query: 697 PRAASQQEIEQSIETLNMLMLDLEPASAAAPLHKSQSVP-------GAWPGASPLSSQPL 749
P AA +QE+++ + + A L + G +PG P S+
Sbjct: 533 PTAAERQELDRLLGGCGVASGGRGAGRETAILDDEEQPTVGGGPHLGVYPGHRPGLSRHC 592
Query: 750 SGSSRQSHPLTQSRSGY-----------IPSGHSLGTPEPAPRASLESVPPGRSYSP--Y 796
S P GY + G G+P+ AS+E RS S Y
Sbjct: 593 SCRQGYREPCGVPNGGYYRPEGTLERRRLAYGGYEGSPQGYAEASMEKRRLCRSLSEGLY 652
Query: 797 DYQPCLAGP-NQDFHSKSPA--------SSSLPAFLPTTHSPPGPQQPPASLPGL----- 842
Y P + P DF ++P LPA P P A+L GL
Sbjct: 653 PYPPEMGKPATGDFGYRAPGYREVVILEDPGLPALYPCPACEEKLALPTAALYGLRLERE 712
Query: 843 --------TAQPLLSPKEATSD-----PSRTPEEEPLNLEGLVAHRVAGVQARE------ 883
+PLL P P+ P+ + AG + E
Sbjct: 713 AGEGWASEAGKPLLHPVRPGHPLPLLLPACGHHHAPMPDYSCLKPPKAGEEGHEGCSYTM 772
Query: 884 ---------------------KQPAEPPAPLR--RRAASDGQYENQ-SPEATSPR----S 915
P+ PA R S G+ SP A SPR S
Sbjct: 773 CPEGRYGHPGYPALVTYSYGGAVPSYCPAYGRVPHSCGSPGEGRGYPSPGAHSPRAGSIS 832
Query: 916 PGVRSPVQCVSPELALTIALNPGGR--PKEPHLHSY-----KEAFEEM---EGTSPSSPP 965
PG SP S +L+ I GG P HL S E+ E + EG S S
Sbjct: 833 PG--SPPYPQSRKLSYEIPTEEGGDRYPLPGHLASAGPLASAESLEPVSWREGPSGHSTL 890
Query: 966 PSGVRSPPGLAKTPLSALGLKPHNPADILLHPTGVTRRRIQPEEDEGKVVVRLSEEPRSY 1025
P R P A + LS H + + +GK R +
Sbjct: 891 PRSPRDAPCSASSELSGPSTPLHTSSPV-----------------QGKESTRRQD----- 928
Query: 1026 VESVARTAVAGPRAQDSEPKSFSAPATQAYGHEIPLRNGTLGGSFVSPSPLSTSSPILSA 1085
R+ + P Q P P +QA + P G ++PSP+S + P S
Sbjct: 929 ----TRSPTSAP-TQRLSPGEALPPVSQAGTGKAPELPSGSGPEPLAPSPVSPTFPPSSP 983
Query: 1086 DSTSVGSFPSGESSDQGPRTP---TQPLLESGFRSGSLGQP-SPSAQRNYQSSSPLPTVG 1141
P G S PR+P T P L G G P SP S +P +
Sbjct: 984 SDWPQERSPGGHSDGASPRSPVPTTLPGLRHAPWQGPRGPPDSPDGSPLTPVPSQMPWLV 1043
Query: 1142 SSYSSPDYSLQHFSSSPESQARAQFSVAGVHTVPGSPQARHRTVGTNTPPSPGFGWRAIN 1201
+S P S +P A + G+ + P P+ RH P PG
Sbjct: 1044 ASPEPP-----QSSPTPAFPLAASYDTNGL-SQPPLPEKRHL-------PGPGQQPGPWG 1090
Query: 1202 PSMAAPSSPSLSHHQMMGP 1220
P A+ + +SHH P
Sbjct: 1091 PEQASSPARGISHHVTFAP 1109
Score = 43.9 bits (102), Expect = 0.001
Identities = 98/406 (24%), Positives = 139/406 (34%), Gaps = 63/406 (15%)
Query: 464 RSRPAGGSAVPSSGRHV-VPAQVHVNGGALASERETDILDDELPNQDGHSAGSMGTLSSL 522
R P+G S +P S R A ++G + L P Q S T S
Sbjct: 881 REGPSGHSTLPRSPRDAPCSASSELSGPSTP-------LHTSSPVQGKESTRRQDTRSPT 933
Query: 523 DGVTNTSEGGYPEALSPLTNGLDKSYPMEPMVNGGGYPYESASRAGPAHAGHTAPMRPSY 582
T G EAL P++ P P +G G + S P P PS
Sbjct: 934 SAPTQRLSPG--EALPPVSQAGTGKAPELP--SGSGPEPLAPSPVSPTFP----PSSPSD 985
Query: 583 SAQEGLAGYQREGPHPAWPQPVTTSHYAH----DPSGMFRSQSFSEAEP---QLP----- 630
QE G +G P P P T H P G S S P Q+P
Sbjct: 986 WPQERSPGGHSDGASPRSPVPTTLPGLRHAPWQGPRGPPDSPDGSPLTPVPSQMPWLVAS 1045
Query: 631 PAPVRGGSSRE---AVQRGLNSWQQQQQQQQQPRPPPRQQ------ERAHLESL-VASRP 680
P P + + A N Q +++ P P QQ E+A + ++
Sbjct: 1046 PEPPQSSPTPAFPLAASYDTNGLSQPPLPEKRHLPGPGQQPGPWGPEQASSPARGISHHV 1105
Query: 681 SPQPLAETPIPSLPEFPRAASQQEIEQSIETLNM-------------LMLDLEPASAAAP 727
+ PL +P PE P SQ ++ +T L+ D +P A
Sbjct: 1106 TFAPLLSDNVPQTPEPPTQESQSNVKFVQDTSKFWYKPHLSRDQAIALLKDKDPG--AFL 1163
Query: 728 LHKSQSVPGAWPGASPLSSQPLSGSSRQSHPLTQSRSGYI----PSGHSL-GTPEPAPRA 782
+ S S GA+ A +++ P S + P+ Q ++ P G + G P
Sbjct: 1164 IRDSHSFQGAYGLALKVATPPPSAQPWKGDPVEQLVRHFLIETGPKGVKIKGCPSEPYFG 1223
Query: 783 SLESVPPGRSYSPYDYQPCLAGPNQDFHSKSPASSSLPAFLPTTHS 828
SL ++ S SP CL P SK P + A +PT S
Sbjct: 1224 SLSALVSQHSISPISLPCCLRIP-----SKDPLEETPEAPVPTNMS 1264
Score = 39.3 bits (90), Expect = 0.034
Identities = 69/281 (24%), Positives = 98/281 (34%), Gaps = 71/281 (25%)
Query: 1190 PPSPGFGWRAINPSMAAPSSPSLSHHQMMGPPGTGFHG----STVSSPQSSAATTPGSPS 1245
P PG + P+ +P + + + PP G G S P+ PG P+
Sbjct: 728 PVRPGHPLPLLLPACGHHHAP-MPDYSCLKPPKAGEEGHEGCSYTMCPEGRYGH-PGYPA 785
Query: 1246 LCRHPAG--VYQVSGLHNKVATTPGSPSLGRHPGAHQGNLASGLHSNAIASPGSPSLGRH 1303
L + G V + +V + GSP GR G PS G H
Sbjct: 786 LVTYSYGGAVPSYCPAYGRVPHSCGSPGEGR---------------------GYPSPGAH 824
Query: 1304 LGGSGSVVPGSP---------------------CLDRHVAYGG-YSTPEDRRPTLSRQ-- 1339
+GS+ PGSP L H+A G ++ E P R+
Sbjct: 825 SPRAGSISPGSPPYPQSRKLSYEIPTEEGGDRYPLPGHLASAGPLASAESLEPVSWREGP 884
Query: 1340 ---------------SSASGYQAPSTPSFPVSPAYYPGLSSPATSPSPDSAAFRQGSPTP 1384
S++S PSTP SP + + SP SA ++ SP
Sbjct: 885 SGHSTLPRSPRDAPCSASSELSGPSTPLHTSSPVQGKESTRRQDTRSPTSAPTQRLSPGE 944
Query: 1385 ALPEKRRMSVGDRAGSLPNYATINGKVSSPVASGM--SSPS 1423
ALP + G +A LP+ + SPV+ SSPS
Sbjct: 945 ALPPVSQAGTG-KAPELPSGSGPEPLAPSPVSPTFPPSSPS 984
>gi|38787941 tensin like C1 domain containing phosphatase isoform 1
[Homo sapiens]
Length = 1419
Score = 499 bits (1285), Expect = e-141
Identities = 367/1022 (35%), Positives = 499/1022 (48%), Gaps = 145/1022 (14%)
Query: 2 SVSRTMEDSCELDLVYVTERIIAVSFPSTANEENFRSNLREVAQMLKSKHGGNYLLFNLS 61
S+ ME +LDL YVTERI+A +FP+ +E+ R +LRE+A +L+SKH YLLFNLS
Sbjct: 130 SLDPLMERRWDLDLTYVTERILAAAFPARPDEQRHRGHLRELAHVLQSKHRDKYLLFNLS 189
Query: 62 ERRPDITKLHAKVLEFGWPDLHTPALEKICSICKAMDTWLNADPHNVVVLHNKGNRGRIG 121
E+R D+T+L+ KV +FGWP+LH P L+K+CSICKAM+TWL+ADP +VVVL+ KGN+G++G
Sbjct: 190 EKRHDLTRLNPKVQDFGWPELHAPPLDKLCSICKAMETWLSADPQHVVVLYCKGNKGKLG 249
Query: 122 VVIAAYMHYSNISASADQALDRFAMKRFYEDKIVPIGQPSQRRYVHYFSGLLSGSIKMNN 181
V+++AYMHYS ISA ADQAL M++F EDK+ QPSQRRY+ YFSGLLSGSI+MN+
Sbjct: 250 VIVSAYMHYSKISAGADQALATLTMRKFCEDKVATELQPSQRRYISYFSGLLSGSIRMNS 309
Query: 182 KPLFLHHVIMHGIPNFESKGGCRPFLRIYQAMQPVYTSGIYNIPGDSQTSVCITIEPGLL 241
PLFLH+V++ +P FE G +PFL+IYQ+MQ VYTSG+Y+I G +CI++EP LL
Sbjct: 310 SPLFLHYVLIPMLPAFEPGTGFQPFLKIYQSMQLVYTSGVYHIAGPGPQQLCISLEPALL 369
Query: 242 LKGDILLKCYHKKFRSPARDVIFRVQFHTCAIHDLGVVFGKEDLDDAFKDDRFPEYGKVE 301
LKGD+++ CYHK R R ++FRVQFHTC IH + F K+ LD+A+ D+RFP VE
Sbjct: 370 LKGDVMVTCYHKGGRGTDRTLVFRVQFHTCTIHGPQLTFPKDQLDEAWTDERFPFQASVE 429
Query: 302 FVFSYGPEKIQGMEHLENGPSVSVDYNTSDPLIRWDSYDNFSGHRDDGMEEVVGHTQGPL 361
FVFS PEKI+G N PSVSVDYNT++P +RWDSY+NF+ H +D ++ + HT+GPL
Sbjct: 430 FVFSSSPEKIKGSTP-RNDPSVSVDYNTTEPAVRWDSYENFNQHHEDSVDGSLTHTRGPL 488
Query: 362 DGSLYAKVKKKDSLHGSTGAVNATRPTLSATPNHVEHTLSVSSDSGNSTASTKTDKTDEP 421
DGS YA+V++ T P S P LSVSSDSG+S ST T +
Sbjct: 489 DGSPYAQVQRPP---------RQTPPAPSPEP-PPPPMLSVSSDSGHS--STLTTEPAAE 536
Query: 422 VPGASSATAALSPQEKRELDRLLSGFGLEREKQGAMYHTQHL--RSRPAGGSAV------ 473
PG TAA E++ELDRLL G G+ +GA T L +P G
Sbjct: 537 SPGRPPPTAA----ERQELDRLLGGCGVASGGRGAGRETAILDDEEQPTVGGGPHLGVYP 592
Query: 474 ---PSSGRHVVPAQVH------VNGGALASERETDILDDELPNQDGHSAG-SMGTLSSLD 523
P RH Q + NGG E + +G G + ++
Sbjct: 593 GHRPGLSRHCSCRQGYREPCGVPNGGYYRPEGTLERRRLAYGGYEGSPQGYAEASMEKRR 652
Query: 524 GVTNTSEGGY---PEALSPLTN------------------GLDKSYPM------------ 550
+ SEG Y PE P T GL YP
Sbjct: 653 LCRSLSEGLYPYPPEMGKPATGDFGYRAPGYREVVILEDPGLPALYPCPACEEKLALPTA 712
Query: 551 ------------EPMVNGGGYPYESASRAG-------PAHAGHTAPM------RPSYSAQ 585
E + G P R G PA H APM +P + +
Sbjct: 713 ALYGLRLEREAGEGWASEAGKPLLHPVRPGHPLPLLLPACGHHHAPMPDYSCLKPPKAGE 772
Query: 586 EGLAGYQ----REG--PHPAWPQPVTTSHYAHDPS-----GMFRSQSFSEAEPQLPPAPV 634
EG G EG HP +P VT S+ PS G S E + P+P
Sbjct: 773 EGHEGCSYTMCPEGRYGHPGYPALVTYSYGGAVPSYCPAYGRVPHSCGSPGEGRGYPSPG 832
Query: 635 RGGSSREAVQRGLNSWQQQQQQQQQ---PRPPPRQQERAHLESL--VASRPSPQPLAETP 689
++ G + Q ++ + R HL S +AS S +P++
Sbjct: 833 AHSPRAGSISPGSPPYPQSRKLSYEIPTEEGGDRYPLPGHLASAGPLASAESLEPVSWRE 892
Query: 690 IPS----LPEFPRAASQQEIEQSIETLNMLMLDLEPASAAAPLHKSQSVPGAWPGASPLS 745
PS LP PR A E + + PLH S V G +
Sbjct: 893 GPSGHSTLPRSPRDAP-------------CSASSELSGPSTPLHTSSPVQGKESTRRQDT 939
Query: 746 SQPLSGSSRQSH------PLTQSRSGYIPSGHSLGTPEPAPRASLESVPPGRSYSPYDYQ 799
P S +++ P++Q+ +G P S PEP + + P S S + +
Sbjct: 940 RSPTSAPTQRLSPGEALPPVSQAGTGKAPELPSGSGPEPLAPSPVSPTFPPSSPSDWPQE 999
Query: 800 PCLAGPNQDFHSKSPASSSLPAFLPTTHSP-PGPQQPPASLPGLTAQPLLSPKEATSDPS 858
G + +SP ++LP H+P GP+ PP S G P+ S
Sbjct: 1000 RSPGGHSDGASPRSPVPTTLPGL---RHAPWQGPRGPPDSPDGSPLTPVPSQMPWLVASP 1056
Query: 859 RTPEEEPLNLEGLVA-HRVAGVQAREKQPAEPPAPLRRRAASDGQYENQ-SPEATSPRSP 916
P+ P L A + G+ ++PP P +R GQ PE S +
Sbjct: 1057 EPPQSSPTPAFPLAASYDTNGL-------SQPPLPEKRHLPGPGQQPGPWGPEQASSPAR 1109
Query: 917 GV 918
G+
Sbjct: 1110 GI 1111
Score = 409 bits (1052), Expect = e-114
Identities = 269/636 (42%), Positives = 365/636 (57%), Gaps = 69/636 (10%)
Query: 1116 RSGSLGQPSPSAQRNYQSSSPLPTV--GSSYSSPDYSLQHFSSSPESQARAQFSVAGVHT 1173
R+GS+ SP ++ + S +PT G Y P + S+ P + A + V+
Sbjct: 837 RAGSISPGSPPYPQSRKLSYEIPTEEGGDRYPLPGHLA---SAGPLASAESLEPVSWREG 893
Query: 1174 VPGSPQARHRTVGTNTPPSPGFGWRAINPSMAAPSSPSLSHHQMMGPPGTGFHGSTVSSP 1233
G H T+ P SP + + ++ PS+P + + G T + +
Sbjct: 894 PSG-----HSTL----PRSPRDAPCSASSELSGPSTPLHTSSPVQGKESTRRQDTRSPTS 944
Query: 1234 QSSAATTPGSPSLCRHPAGVYQVSGLHN-----KVATTPGSPSLG-RHPGAHQGNLASGL 1287
+ +PG AG + L + +A +P SP+ P + G
Sbjct: 945 APTQRLSPGEALPPVSQAGTGKAPELPSGSGPEPLAPSPVSPTFPPSSPSDWPQERSPGG 1004
Query: 1288 HSNAIASPGSPSLGRHLGGSGSVVPGSPCLDRHVAYGGYSTPEDRRPTLSRQSSASGYQA 1347
HS+ ASP SP + +PG RH + G P D S G +
Sbjct: 1005 HSDG-ASPRSPV--------PTTLPGL----RHAPWQGPRGPPD---------SPDG--S 1040
Query: 1348 PSTPSFPVSPAYYPGLSSPATSPSPDSAAFRQGSPTPALPEKRRMSV-GDRAGSLPNYAT 1406
P TP P+ P L SP P Q SPTPA P G LP
Sbjct: 1041 PLTPV----PSQMPWL---VASPEPP-----QSSPTPAFPLAASYDTNGLSQPPLPEKRH 1088
Query: 1407 INGKVSSPVASG---MSSPSGGST--VSFSHTLPDFSKYSMPDNSPETRAKVKFVQDTSK 1461
+ G P G SSP+ G + V+F+ L D + + E+++ VKFVQDTSK
Sbjct: 1089 LPGPGQQPGPWGPEQASSPARGISHHVTFAPLLSDNVPQTPEPPTQESQSNVKFVQDTSK 1148
Query: 1462 YWYKPEISREQAIALLKDQEPGAFIIRDSHSFRGAYGLAMKVSSPPPTIMQQNKKGDMTH 1521
+WYKP +SR+QAIALLKD++PGAF+IRDSHSF+GAYGLA+KV++PPP+ Q KGD
Sbjct: 1149 FWYKPHLSRDQAIALLKDKDPGAFLIRDSHSFQGAYGLALKVATPPPSA--QPWKGDPVE 1206
Query: 1522 ELVRHFLIETGPRGVKLKGCPNEPNFGSLSALVYQHSIIPLALPCKLVIPNRDPTDESKD 1581
+LVRHFLIETGP+GVK+KGCP+EP FGSLSALV QHSI P++LPC L IP++DP +E+ +
Sbjct: 1207 QLVRHFLIETGPKGVKIKGCPSEPYFGSLSALVSQHSISPISLPCCLRIPSKDPLEETPE 1266
Query: 1582 SSGPAN--STADLLKQGAACNVLFVNSVDMESLTGPQAISKATSETLAADPTPAATIVHF 1639
+ P N + ADLL+QGAAC+VL++ SV+ ESLTGPQA+++A+S L+ P P +VHF
Sbjct: 1267 APVPTNMSTAADLLRQGAACSVLYLTSVETESLTGPQAVARASSAALSCSPRPTPAVVHF 1326
Query: 1640 KVSAQGITLTDNQRKLFFRRHYPLNTVTFCDLDPQERKWMKTEGGAPAKLFGFVARKQGS 1699
KVSAQGITLTDNQRKLFFRRHYP+N++TF DPQ+R+W + G +K+FGFVA+K GS
Sbjct: 1327 KVSAQGITLTDNQRKLFFRRHYPVNSITFSSTDPQDRRWTNPD-GTTSKIFGFVAKKPGS 1385
Query: 1700 TTDNACHLFAELDPNQPASAIVNFVSKVMLNAGQKR 1735
+N CHLFAELDP+QPA AIV F++KV+L GQ++
Sbjct: 1386 PWENVCHLFAELDPDQPAGAIVTFITKVLL--GQRK 1419
Score = 53.1 bits (126), Expect = 2e-06
Identities = 159/679 (23%), Positives = 218/679 (32%), Gaps = 144/679 (21%)
Query: 637 GSSREAVQRGLNSWQQQQQQQQQPRPPPRQQERAHLESLVASRPSPQPLAETPIPSLPEF 696
GS VQR +Q P PPP +S +S + +P AE+P P
Sbjct: 490 GSPYAQVQRP----PRQTPPAPSPEPPPPPMLSVSSDSGHSSTLTTEPAAESP--GRPP- 542
Query: 697 PRAASQQEIEQSIETLNMLMLDLEPASAAAPLHKSQSVP-------GAWPGASPLSSQPL 749
P AA +QE+++ + + A L + G +PG P S+
Sbjct: 543 PTAAERQELDRLLGGCGVASGGRGAGRETAILDDEEQPTVGGGPHLGVYPGHRPGLSRHC 602
Query: 750 SGSSRQSHPLTQSRSGY-----------IPSGHSLGTPEPAPRASLESVPPGRSYSP--Y 796
S P GY + G G+P+ AS+E RS S Y
Sbjct: 603 SCRQGYREPCGVPNGGYYRPEGTLERRRLAYGGYEGSPQGYAEASMEKRRLCRSLSEGLY 662
Query: 797 DYQPCLAGP-NQDFHSKSPA--------SSSLPAFLPTTHSPPGPQQPPASLPGL----- 842
Y P + P DF ++P LPA P P A+L GL
Sbjct: 663 PYPPEMGKPATGDFGYRAPGYREVVILEDPGLPALYPCPACEEKLALPTAALYGLRLERE 722
Query: 843 --------TAQPLLSPKEATSD-----PSRTPEEEPLNLEGLVAHRVAGVQARE------ 883
+PLL P P+ P+ + AG + E
Sbjct: 723 AGEGWASEAGKPLLHPVRPGHPLPLLLPACGHHHAPMPDYSCLKPPKAGEEGHEGCSYTM 782
Query: 884 ---------------------KQPAEPPAPLR--RRAASDGQYENQ-SPEATSPR----S 915
P+ PA R S G+ SP A SPR S
Sbjct: 783 CPEGRYGHPGYPALVTYSYGGAVPSYCPAYGRVPHSCGSPGEGRGYPSPGAHSPRAGSIS 842
Query: 916 PGVRSPVQCVSPELALTIALNPGGR--PKEPHLHSY-----KEAFEEM---EGTSPSSPP 965
PG SP S +L+ I GG P HL S E+ E + EG S S
Sbjct: 843 PG--SPPYPQSRKLSYEIPTEEGGDRYPLPGHLASAGPLASAESLEPVSWREGPSGHSTL 900
Query: 966 PSGVRSPPGLAKTPLSALGLKPHNPADILLHPTGVTRRRIQPEEDEGKVVVRLSEEPRSY 1025
P R P A + LS H + + +GK R +
Sbjct: 901 PRSPRDAPCSASSELSGPSTPLHTSSPV-----------------QGKESTRRQD----- 938
Query: 1026 VESVARTAVAGPRAQDSEPKSFSAPATQAYGHEIPLRNGTLGGSFVSPSPLSTSSPILSA 1085
R+ + P Q P P +QA + P G ++PSP+S + P S
Sbjct: 939 ----TRSPTSAP-TQRLSPGEALPPVSQAGTGKAPELPSGSGPEPLAPSPVSPTFPPSSP 993
Query: 1086 DSTSVGSFPSGESSDQGPRTP---TQPLLESGFRSGSLGQP-SPSAQRNYQSSSPLPTVG 1141
P G S PR+P T P L G G P SP S +P +
Sbjct: 994 SDWPQERSPGGHSDGASPRSPVPTTLPGLRHAPWQGPRGPPDSPDGSPLTPVPSQMPWLV 1053
Query: 1142 SSYSSPDYSLQHFSSSPESQARAQFSVAGVHTVPGSPQARHRTVGTNTPPSPGFGWRAIN 1201
+S P S +P A + G+ + P P+ RH P PG
Sbjct: 1054 ASPEPP-----QSSPTPAFPLAASYDTNGL-SQPPLPEKRHL-------PGPGQQPGPWG 1100
Query: 1202 PSMAAPSSPSLSHHQMMGP 1220
P A+ + +SHH P
Sbjct: 1101 PEQASSPARGISHHVTFAP 1119
Score = 43.9 bits (102), Expect = 0.001
Identities = 98/406 (24%), Positives = 139/406 (34%), Gaps = 63/406 (15%)
Query: 464 RSRPAGGSAVPSSGRHV-VPAQVHVNGGALASERETDILDDELPNQDGHSAGSMGTLSSL 522
R P+G S +P S R A ++G + L P Q S T S
Sbjct: 891 REGPSGHSTLPRSPRDAPCSASSELSGPSTP-------LHTSSPVQGKESTRRQDTRSPT 943
Query: 523 DGVTNTSEGGYPEALSPLTNGLDKSYPMEPMVNGGGYPYESASRAGPAHAGHTAPMRPSY 582
T G EAL P++ P P +G G + S P P PS
Sbjct: 944 SAPTQRLSPG--EALPPVSQAGTGKAPELP--SGSGPEPLAPSPVSPTFP----PSSPSD 995
Query: 583 SAQEGLAGYQREGPHPAWPQPVTTSHYAH----DPSGMFRSQSFSEAEP---QLP----- 630
QE G +G P P P T H P G S S P Q+P
Sbjct: 996 WPQERSPGGHSDGASPRSPVPTTLPGLRHAPWQGPRGPPDSPDGSPLTPVPSQMPWLVAS 1055
Query: 631 PAPVRGGSSRE---AVQRGLNSWQQQQQQQQQPRPPPRQQ------ERAHLESL-VASRP 680
P P + + A N Q +++ P P QQ E+A + ++
Sbjct: 1056 PEPPQSSPTPAFPLAASYDTNGLSQPPLPEKRHLPGPGQQPGPWGPEQASSPARGISHHV 1115
Query: 681 SPQPLAETPIPSLPEFPRAASQQEIEQSIETLNM-------------LMLDLEPASAAAP 727
+ PL +P PE P SQ ++ +T L+ D +P A
Sbjct: 1116 TFAPLLSDNVPQTPEPPTQESQSNVKFVQDTSKFWYKPHLSRDQAIALLKDKDPG--AFL 1173
Query: 728 LHKSQSVPGAWPGASPLSSQPLSGSSRQSHPLTQSRSGYI----PSGHSL-GTPEPAPRA 782
+ S S GA+ A +++ P S + P+ Q ++ P G + G P
Sbjct: 1174 IRDSHSFQGAYGLALKVATPPPSAQPWKGDPVEQLVRHFLIETGPKGVKIKGCPSEPYFG 1233
Query: 783 SLESVPPGRSYSPYDYQPCLAGPNQDFHSKSPASSSLPAFLPTTHS 828
SL ++ S SP CL P SK P + A +PT S
Sbjct: 1234 SLSALVSQHSISPISLPCCLRIP-----SKDPLEETPEAPVPTNMS 1274
Score = 39.3 bits (90), Expect = 0.034
Identities = 69/281 (24%), Positives = 98/281 (34%), Gaps = 71/281 (25%)
Query: 1190 PPSPGFGWRAINPSMAAPSSPSLSHHQMMGPPGTGFHG----STVSSPQSSAATTPGSPS 1245
P PG + P+ +P + + + PP G G S P+ PG P+
Sbjct: 738 PVRPGHPLPLLLPACGHHHAP-MPDYSCLKPPKAGEEGHEGCSYTMCPEGRYGH-PGYPA 795
Query: 1246 LCRHPAG--VYQVSGLHNKVATTPGSPSLGRHPGAHQGNLASGLHSNAIASPGSPSLGRH 1303
L + G V + +V + GSP GR G PS G H
Sbjct: 796 LVTYSYGGAVPSYCPAYGRVPHSCGSPGEGR---------------------GYPSPGAH 834
Query: 1304 LGGSGSVVPGSP---------------------CLDRHVAYGG-YSTPEDRRPTLSRQ-- 1339
+GS+ PGSP L H+A G ++ E P R+
Sbjct: 835 SPRAGSISPGSPPYPQSRKLSYEIPTEEGGDRYPLPGHLASAGPLASAESLEPVSWREGP 894
Query: 1340 ---------------SSASGYQAPSTPSFPVSPAYYPGLSSPATSPSPDSAAFRQGSPTP 1384
S++S PSTP SP + + SP SA ++ SP
Sbjct: 895 SGHSTLPRSPRDAPCSASSELSGPSTPLHTSSPVQGKESTRRQDTRSPTSAPTQRLSPGE 954
Query: 1385 ALPEKRRMSVGDRAGSLPNYATINGKVSSPVASGM--SSPS 1423
ALP + G +A LP+ + SPV+ SSPS
Sbjct: 955 ALPPVSQAGTG-KAPELPSGSGPEPLAPSPVSPTFPPSSPS 994
>gi|38787970 tensin like C1 domain containing phosphatase isoform 3
[Homo sapiens]
Length = 1285
Score = 498 bits (1283), Expect = e-140
Identities = 366/1017 (35%), Positives = 497/1017 (48%), Gaps = 145/1017 (14%)
Query: 7 MEDSCELDLVYVTERIIAVSFPSTANEENFRSNLREVAQMLKSKHGGNYLLFNLSERRPD 66
ME +LDL YVTERI+A +FP+ +E+ R +LRE+A +L+SKH YLLFNLSE+R D
Sbjct: 1 MERRWDLDLTYVTERILAAAFPARPDEQRHRGHLRELAHVLQSKHRDKYLLFNLSEKRHD 60
Query: 67 ITKLHAKVLEFGWPDLHTPALEKICSICKAMDTWLNADPHNVVVLHNKGNRGRIGVVIAA 126
+T+L+ KV +FGWP+LH P L+K+CSICKAM+TWL+ADP +VVVL+ KGN+G++GV+++A
Sbjct: 61 LTRLNPKVQDFGWPELHAPPLDKLCSICKAMETWLSADPQHVVVLYCKGNKGKLGVIVSA 120
Query: 127 YMHYSNISASADQALDRFAMKRFYEDKIVPIGQPSQRRYVHYFSGLLSGSIKMNNKPLFL 186
YMHYS ISA ADQAL M++F EDK+ QPSQRRY+ YFSGLLSGSI+MN+ PLFL
Sbjct: 121 YMHYSKISAGADQALATLTMRKFCEDKVATELQPSQRRYISYFSGLLSGSIRMNSSPLFL 180
Query: 187 HHVIMHGIPNFESKGGCRPFLRIYQAMQPVYTSGIYNIPGDSQTSVCITIEPGLLLKGDI 246
H+V++ +P FE G +PFL+IYQ+MQ VYTSG+Y+I G +CI++EP LLLKGD+
Sbjct: 181 HYVLIPMLPAFEPGTGFQPFLKIYQSMQLVYTSGVYHIAGPGPQQLCISLEPALLLKGDV 240
Query: 247 LLKCYHKKFRSPARDVIFRVQFHTCAIHDLGVVFGKEDLDDAFKDDRFPEYGKVEFVFSY 306
++ CYHK R R ++FRVQFHTC IH + F K+ LD+A+ D+RFP VEFVFS
Sbjct: 241 MVTCYHKGGRGTDRTLVFRVQFHTCTIHGPQLTFPKDQLDEAWTDERFPFQASVEFVFSS 300
Query: 307 GPEKIQGMEHLENGPSVSVDYNTSDPLIRWDSYDNFSGHRDDGMEEVVGHTQGPLDGSLY 366
PEKI+G N PSVSVDYNT++P +RWDSY+NF+ H +D ++ + HT+GPLDGS Y
Sbjct: 301 SPEKIKGSTP-RNDPSVSVDYNTTEPAVRWDSYENFNQHHEDSVDGSLTHTRGPLDGSPY 359
Query: 367 AKVKKKDSLHGSTGAVNATRPTLSATPNHVEHTLSVSSDSGNSTASTKTDKTDEPVPGAS 426
A+V++ T P S P LSVSSDSG+S ST T + PG
Sbjct: 360 AQVQRPP---------RQTPPAPSPEP-PPPPMLSVSSDSGHS--STLTTEPAAESPGRP 407
Query: 427 SATAALSPQEKRELDRLLSGFGLEREKQGAMYHTQHL--RSRPAGGSAV---------PS 475
TAA E++ELDRLL G G+ +GA T L +P G P
Sbjct: 408 PPTAA----ERQELDRLLGGCGVASGGRGAGRETAILDDEEQPTVGGGPHLGVYPGHRPG 463
Query: 476 SGRHVVPAQVH------VNGGALASERETDILDDELPNQDGHSAG-SMGTLSSLDGVTNT 528
RH Q + NGG E + +G G + ++ +
Sbjct: 464 LSRHCSCRQGYREPCGVPNGGYYRPEGTLERRRLAYGGYEGSPQGYAEASMEKRRLCRSL 523
Query: 529 SEGGY---PEALSPLTN------------------GLDKSYPM----------------- 550
SEG Y PE P T GL YP
Sbjct: 524 SEGLYPYPPEMGKPATGDFGYRAPGYREVVILEDPGLPALYPCPACEEKLALPTAALYGL 583
Query: 551 -------EPMVNGGGYPYESASRAG-------PAHAGHTAPM------RPSYSAQEGLAG 590
E + G P R G PA H APM +P + +EG G
Sbjct: 584 RLEREAGEGWASEAGKPLLHPVRPGHPLPLLLPACGHHHAPMPDYSCLKPPKAGEEGHEG 643
Query: 591 YQ----REG--PHPAWPQPVTTSHYAHDPS-----GMFRSQSFSEAEPQLPPAPVRGGSS 639
EG HP +P VT S+ PS G S E + P+P
Sbjct: 644 CSYTMCPEGRYGHPGYPALVTYSYGGAVPSYCPAYGRVPHSCGSPGEGRGYPSPGAHSPR 703
Query: 640 REAVQRGLNSWQQQQQQQQQ---PRPPPRQQERAHLESL--VASRPSPQPLAETPIPS-- 692
++ G + Q ++ + R HL S +AS S +P++ PS
Sbjct: 704 AGSISPGSPPYPQSRKLSYEIPTEEGGDRYPLPGHLASAGPLASAESLEPVSWREGPSGH 763
Query: 693 --LPEFPRAASQQEIEQSIETLNMLMLDLEPASAAAPLHKSQSVPGAWPGASPLSSQPLS 750
LP PR A E + + PLH S V G + P S
Sbjct: 764 STLPRSPRDAP-------------CSASSELSGPSTPLHTSSPVQGKESTRRQDTRSPTS 810
Query: 751 GSSRQSH------PLTQSRSGYIPSGHSLGTPEPAPRASLESVPPGRSYSPYDYQPCLAG 804
+++ P++Q+ +G P S PEP + + P S S + + G
Sbjct: 811 APTQRLSPGEALPPVSQAGTGKAPELPSGSGPEPLAPSPVSPTFPPSSPSDWPQERSPGG 870
Query: 805 PNQDFHSKSPASSSLPAFLPTTHSP-PGPQQPPASLPGLTAQPLLSPKEATSDPSRTPEE 863
+ +SP ++LP H+P GP+ PP S G P+ S P+
Sbjct: 871 HSDGASPRSPVPTTLPGL---RHAPWQGPRGPPDSPDGSPLTPVPSQMPWLVASPEPPQS 927
Query: 864 EPLNLEGLVA-HRVAGVQAREKQPAEPPAPLRRRAASDGQYENQ-SPEATSPRSPGV 918
P L A + G+ ++PP P +R GQ PE S + G+
Sbjct: 928 SPTPAFPLAASYDTNGL-------SQPPLPEKRHLPGPGQQPGPWGPEQASSPARGI 977
Score = 409 bits (1052), Expect = e-114
Identities = 269/636 (42%), Positives = 365/636 (57%), Gaps = 69/636 (10%)
Query: 1116 RSGSLGQPSPSAQRNYQSSSPLPTV--GSSYSSPDYSLQHFSSSPESQARAQFSVAGVHT 1173
R+GS+ SP ++ + S +PT G Y P + S+ P + A + V+
Sbjct: 703 RAGSISPGSPPYPQSRKLSYEIPTEEGGDRYPLPGHLA---SAGPLASAESLEPVSWREG 759
Query: 1174 VPGSPQARHRTVGTNTPPSPGFGWRAINPSMAAPSSPSLSHHQMMGPPGTGFHGSTVSSP 1233
G H T+ P SP + + ++ PS+P + + G T + +
Sbjct: 760 PSG-----HSTL----PRSPRDAPCSASSELSGPSTPLHTSSPVQGKESTRRQDTRSPTS 810
Query: 1234 QSSAATTPGSPSLCRHPAGVYQVSGLHN-----KVATTPGSPSLG-RHPGAHQGNLASGL 1287
+ +PG AG + L + +A +P SP+ P + G
Sbjct: 811 APTQRLSPGEALPPVSQAGTGKAPELPSGSGPEPLAPSPVSPTFPPSSPSDWPQERSPGG 870
Query: 1288 HSNAIASPGSPSLGRHLGGSGSVVPGSPCLDRHVAYGGYSTPEDRRPTLSRQSSASGYQA 1347
HS+ ASP SP + +PG RH + G P D S G +
Sbjct: 871 HSDG-ASPRSPV--------PTTLPGL----RHAPWQGPRGPPD---------SPDG--S 906
Query: 1348 PSTPSFPVSPAYYPGLSSPATSPSPDSAAFRQGSPTPALPEKRRMSV-GDRAGSLPNYAT 1406
P TP P+ P L SP P Q SPTPA P G LP
Sbjct: 907 PLTPV----PSQMPWL---VASPEPP-----QSSPTPAFPLAASYDTNGLSQPPLPEKRH 954
Query: 1407 INGKVSSPVASG---MSSPSGGST--VSFSHTLPDFSKYSMPDNSPETRAKVKFVQDTSK 1461
+ G P G SSP+ G + V+F+ L D + + E+++ VKFVQDTSK
Sbjct: 955 LPGPGQQPGPWGPEQASSPARGISHHVTFAPLLSDNVPQTPEPPTQESQSNVKFVQDTSK 1014
Query: 1462 YWYKPEISREQAIALLKDQEPGAFIIRDSHSFRGAYGLAMKVSSPPPTIMQQNKKGDMTH 1521
+WYKP +SR+QAIALLKD++PGAF+IRDSHSF+GAYGLA+KV++PPP+ Q KGD
Sbjct: 1015 FWYKPHLSRDQAIALLKDKDPGAFLIRDSHSFQGAYGLALKVATPPPSA--QPWKGDPVE 1072
Query: 1522 ELVRHFLIETGPRGVKLKGCPNEPNFGSLSALVYQHSIIPLALPCKLVIPNRDPTDESKD 1581
+LVRHFLIETGP+GVK+KGCP+EP FGSLSALV QHSI P++LPC L IP++DP +E+ +
Sbjct: 1073 QLVRHFLIETGPKGVKIKGCPSEPYFGSLSALVSQHSISPISLPCCLRIPSKDPLEETPE 1132
Query: 1582 SSGPAN--STADLLKQGAACNVLFVNSVDMESLTGPQAISKATSETLAADPTPAATIVHF 1639
+ P N + ADLL+QGAAC+VL++ SV+ ESLTGPQA+++A+S L+ P P +VHF
Sbjct: 1133 APVPTNMSTAADLLRQGAACSVLYLTSVETESLTGPQAVARASSAALSCSPRPTPAVVHF 1192
Query: 1640 KVSAQGITLTDNQRKLFFRRHYPLNTVTFCDLDPQERKWMKTEGGAPAKLFGFVARKQGS 1699
KVSAQGITLTDNQRKLFFRRHYP+N++TF DPQ+R+W + G +K+FGFVA+K GS
Sbjct: 1193 KVSAQGITLTDNQRKLFFRRHYPVNSITFSSTDPQDRRWTNPD-GTTSKIFGFVAKKPGS 1251
Query: 1700 TTDNACHLFAELDPNQPASAIVNFVSKVMLNAGQKR 1735
+N CHLFAELDP+QPA AIV F++KV+L GQ++
Sbjct: 1252 PWENVCHLFAELDPDQPAGAIVTFITKVLL--GQRK 1285
Score = 53.1 bits (126), Expect = 2e-06
Identities = 159/679 (23%), Positives = 218/679 (32%), Gaps = 144/679 (21%)
Query: 637 GSSREAVQRGLNSWQQQQQQQQQPRPPPRQQERAHLESLVASRPSPQPLAETPIPSLPEF 696
GS VQR +Q P PPP +S +S + +P AE+P P
Sbjct: 356 GSPYAQVQRP----PRQTPPAPSPEPPPPPMLSVSSDSGHSSTLTTEPAAESP--GRPP- 408
Query: 697 PRAASQQEIEQSIETLNMLMLDLEPASAAAPLHKSQSVP-------GAWPGASPLSSQPL 749
P AA +QE+++ + + A L + G +PG P S+
Sbjct: 409 PTAAERQELDRLLGGCGVASGGRGAGRETAILDDEEQPTVGGGPHLGVYPGHRPGLSRHC 468
Query: 750 SGSSRQSHPLTQSRSGY-----------IPSGHSLGTPEPAPRASLESVPPGRSYSP--Y 796
S P GY + G G+P+ AS+E RS S Y
Sbjct: 469 SCRQGYREPCGVPNGGYYRPEGTLERRRLAYGGYEGSPQGYAEASMEKRRLCRSLSEGLY 528
Query: 797 DYQPCLAGP-NQDFHSKSPA--------SSSLPAFLPTTHSPPGPQQPPASLPGL----- 842
Y P + P DF ++P LPA P P A+L GL
Sbjct: 529 PYPPEMGKPATGDFGYRAPGYREVVILEDPGLPALYPCPACEEKLALPTAALYGLRLERE 588
Query: 843 --------TAQPLLSPKEATSD-----PSRTPEEEPLNLEGLVAHRVAGVQARE------ 883
+PLL P P+ P+ + AG + E
Sbjct: 589 AGEGWASEAGKPLLHPVRPGHPLPLLLPACGHHHAPMPDYSCLKPPKAGEEGHEGCSYTM 648
Query: 884 ---------------------KQPAEPPAPLR--RRAASDGQYENQ-SPEATSPR----S 915
P+ PA R S G+ SP A SPR S
Sbjct: 649 CPEGRYGHPGYPALVTYSYGGAVPSYCPAYGRVPHSCGSPGEGRGYPSPGAHSPRAGSIS 708
Query: 916 PGVRSPVQCVSPELALTIALNPGGR--PKEPHLHSY-----KEAFEEM---EGTSPSSPP 965
PG SP S +L+ I GG P HL S E+ E + EG S S
Sbjct: 709 PG--SPPYPQSRKLSYEIPTEEGGDRYPLPGHLASAGPLASAESLEPVSWREGPSGHSTL 766
Query: 966 PSGVRSPPGLAKTPLSALGLKPHNPADILLHPTGVTRRRIQPEEDEGKVVVRLSEEPRSY 1025
P R P A + LS H + + +GK R +
Sbjct: 767 PRSPRDAPCSASSELSGPSTPLHTSSPV-----------------QGKESTRRQD----- 804
Query: 1026 VESVARTAVAGPRAQDSEPKSFSAPATQAYGHEIPLRNGTLGGSFVSPSPLSTSSPILSA 1085
R+ + P Q P P +QA + P G ++PSP+S + P S
Sbjct: 805 ----TRSPTSAP-TQRLSPGEALPPVSQAGTGKAPELPSGSGPEPLAPSPVSPTFPPSSP 859
Query: 1086 DSTSVGSFPSGESSDQGPRTP---TQPLLESGFRSGSLGQP-SPSAQRNYQSSSPLPTVG 1141
P G S PR+P T P L G G P SP S +P +
Sbjct: 860 SDWPQERSPGGHSDGASPRSPVPTTLPGLRHAPWQGPRGPPDSPDGSPLTPVPSQMPWLV 919
Query: 1142 SSYSSPDYSLQHFSSSPESQARAQFSVAGVHTVPGSPQARHRTVGTNTPPSPGFGWRAIN 1201
+S P S +P A + G+ + P P+ RH P PG
Sbjct: 920 ASPEPP-----QSSPTPAFPLAASYDTNGL-SQPPLPEKRHL-------PGPGQQPGPWG 966
Query: 1202 PSMAAPSSPSLSHHQMMGP 1220
P A+ + +SHH P
Sbjct: 967 PEQASSPARGISHHVTFAP 985
Score = 43.9 bits (102), Expect = 0.001
Identities = 98/406 (24%), Positives = 139/406 (34%), Gaps = 63/406 (15%)
Query: 464 RSRPAGGSAVPSSGRHV-VPAQVHVNGGALASERETDILDDELPNQDGHSAGSMGTLSSL 522
R P+G S +P S R A ++G + L P Q S T S
Sbjct: 757 REGPSGHSTLPRSPRDAPCSASSELSGPSTP-------LHTSSPVQGKESTRRQDTRSPT 809
Query: 523 DGVTNTSEGGYPEALSPLTNGLDKSYPMEPMVNGGGYPYESASRAGPAHAGHTAPMRPSY 582
T G EAL P++ P P +G G + S P P PS
Sbjct: 810 SAPTQRLSPG--EALPPVSQAGTGKAPELP--SGSGPEPLAPSPVSPTFP----PSSPSD 861
Query: 583 SAQEGLAGYQREGPHPAWPQPVTTSHYAH----DPSGMFRSQSFSEAEP---QLP----- 630
QE G +G P P P T H P G S S P Q+P
Sbjct: 862 WPQERSPGGHSDGASPRSPVPTTLPGLRHAPWQGPRGPPDSPDGSPLTPVPSQMPWLVAS 921
Query: 631 PAPVRGGSSRE---AVQRGLNSWQQQQQQQQQPRPPPRQQ------ERAHLESL-VASRP 680
P P + + A N Q +++ P P QQ E+A + ++
Sbjct: 922 PEPPQSSPTPAFPLAASYDTNGLSQPPLPEKRHLPGPGQQPGPWGPEQASSPARGISHHV 981
Query: 681 SPQPLAETPIPSLPEFPRAASQQEIEQSIETLNM-------------LMLDLEPASAAAP 727
+ PL +P PE P SQ ++ +T L+ D +P A
Sbjct: 982 TFAPLLSDNVPQTPEPPTQESQSNVKFVQDTSKFWYKPHLSRDQAIALLKDKDPG--AFL 1039
Query: 728 LHKSQSVPGAWPGASPLSSQPLSGSSRQSHPLTQSRSGYI----PSGHSL-GTPEPAPRA 782
+ S S GA+ A +++ P S + P+ Q ++ P G + G P
Sbjct: 1040 IRDSHSFQGAYGLALKVATPPPSAQPWKGDPVEQLVRHFLIETGPKGVKIKGCPSEPYFG 1099
Query: 783 SLESVPPGRSYSPYDYQPCLAGPNQDFHSKSPASSSLPAFLPTTHS 828
SL ++ S SP CL P SK P + A +PT S
Sbjct: 1100 SLSALVSQHSISPISLPCCLRIP-----SKDPLEETPEAPVPTNMS 1140
Score = 39.3 bits (90), Expect = 0.034
Identities = 69/281 (24%), Positives = 98/281 (34%), Gaps = 71/281 (25%)
Query: 1190 PPSPGFGWRAINPSMAAPSSPSLSHHQMMGPPGTGFHG----STVSSPQSSAATTPGSPS 1245
P PG + P+ +P + + + PP G G S P+ PG P+
Sbjct: 604 PVRPGHPLPLLLPACGHHHAP-MPDYSCLKPPKAGEEGHEGCSYTMCPEGRYGH-PGYPA 661
Query: 1246 LCRHPAG--VYQVSGLHNKVATTPGSPSLGRHPGAHQGNLASGLHSNAIASPGSPSLGRH 1303
L + G V + +V + GSP GR G PS G H
Sbjct: 662 LVTYSYGGAVPSYCPAYGRVPHSCGSPGEGR---------------------GYPSPGAH 700
Query: 1304 LGGSGSVVPGSP---------------------CLDRHVAYGG-YSTPEDRRPTLSRQ-- 1339
+GS+ PGSP L H+A G ++ E P R+
Sbjct: 701 SPRAGSISPGSPPYPQSRKLSYEIPTEEGGDRYPLPGHLASAGPLASAESLEPVSWREGP 760
Query: 1340 ---------------SSASGYQAPSTPSFPVSPAYYPGLSSPATSPSPDSAAFRQGSPTP 1384
S++S PSTP SP + + SP SA ++ SP
Sbjct: 761 SGHSTLPRSPRDAPCSASSELSGPSTPLHTSSPVQGKESTRRQDTRSPTSAPTQRLSPGE 820
Query: 1385 ALPEKRRMSVGDRAGSLPNYATINGKVSSPVASGM--SSPS 1423
ALP + G +A LP+ + SPV+ SSPS
Sbjct: 821 ALPPVSQAGTG-KAPELPSGSGPEPLAPSPVSPTFPPSSPS 860
>gi|157738639 tensin 4 [Homo sapiens]
Length = 715
Score = 317 bits (813), Expect = 5e-86
Identities = 209/501 (41%), Positives = 281/501 (56%), Gaps = 50/501 (9%)
Query: 1267 PGSPSLGRHPGAHQGNLASGLHSNAIASPGSPSLGRHLGGSG-------SVVPGSPCLDR 1319
P SPS+ + + GL S +ASP L + LGG SV+ SP D
Sbjct: 226 PNSPSISIPCMGSKASSPHGLGSPLVASP---RLEKRLGGLAPQRGSRISVLSASPVSDV 282
Query: 1320 HVAYGGYSTPEDRRPTLSRQSSASGYQAPSTPSFPVSPAYYPGLSSPATSPS----PDSA 1375
+G S S QSS+ ++P+ S S + G S T PS P +
Sbjct: 283 SYMFGS-SQSLLHSSNSSHQSSSRSLESPANSS---SSLHSLGSVSLCTRPSDFQAPRNP 338
Query: 1376 AFRQGSP-TPALPEKRRMSVGDRAGSLPN------YATING---KVSSP----------V 1415
G P TP P + S+ N ING SSP V
Sbjct: 339 TLTMGQPRTPHSPPLAKEHASSCPPSITNSMVDIPIVLINGCPEPGSSPPQRTPGHQNSV 398
Query: 1416 ASGMSSPSGG--STVSFSHTLPDFSKYSMPDN-SPETRAKVKFVQDTSKYWYKPEISREQ 1472
G +SPS +T S S TL D + P+ + + + +KFV DTSKYW+KP I+REQ
Sbjct: 399 QPGAASPSNPCPATRSNSQTLSDAPFTTCPEGPARDMQPTMKFVMDTSKYWFKPNITREQ 458
Query: 1473 AIALLKDQEPGAFIIRDSHSFRGAYGLAMKVSSPPPTIMQQNKKGDMTHELVRHFLIETG 1532
AI LL+ +EPGAF+IRDS S+RG++GLA+KV P + Q++ G+ +++L+RHFLIE+
Sbjct: 459 AIELLRKEEPGAFVIRDSSSYRGSFGLALKVQEVPASA--QSRPGEDSNDLIRHFLIESS 516
Query: 1533 PRGVKLKGCPNEPNFGSLSALVYQHSIIPLALPCKLVIPNRD--PTDESKDSSGPANSTA 1590
+GV LKG EP FGSLSA V QHSI+ LALPCKL IP R+ D + DS+ +S A
Sbjct: 517 AKGVHLKGADEEPYFGSLSAFVCQHSIMALALPCKLTIPQRELGGADGASDST---DSPA 573
Query: 1591 DLLKQGAACNVLFVNSVDMESLTGPQAISKATSETLAADPTPAATIVHFKVSAQGITLTD 1650
K+ A C+ L+++SV +E+LTG A+ KA S T D P T+VHFKV+ QGITLTD
Sbjct: 574 SCQKKSAGCHTLYLSSVSVETLTGALAVQKAISTTFERDILPTPTVVHFKVTEQGITLTD 633
Query: 1651 NQRKLFFRRHYPLNTVTFCDLDPQERKWMKTEGGAPAKLFGFVARKQGSTTDNACHLFAE 1710
QRK+FFRRHYPL T+ FC +DP++RKW K P+ +FGFVA+ Q +N CHLFAE
Sbjct: 634 VQRKVFFRRHYPLTTLRFCGMDPEQRKWQKY--CKPSWIFGFVAKSQTEPQENVCHLFAE 691
Query: 1711 LDPNQPASAIVNFVSKVMLNA 1731
D QPAS ++ V+ ++ +A
Sbjct: 692 YDMVQPASQVIGLVTALLQDA 712
>gi|157384971 cyclin G associated kinase [Homo sapiens]
Length = 1311
Score = 145 bits (367), Expect = 3e-34
Identities = 169/694 (24%), Positives = 278/694 (40%), Gaps = 61/694 (8%)
Query: 12 ELDLVYVTERIIAVSFPSTANEENFRSNLREVAQMLKSKHGGNYLLFNLSERRPDITKLH 71
+LD+ Y+T RI +SFP+ E ++N+ +V L SKH G+Y ++NLS R ++ H
Sbjct: 407 DLDISYITSRIAVMSFPAEGVESALKNNIEDVRLFLDSKHPGHYAVYNLSPRTYRPSRFH 466
Query: 72 AKVLEFGWPDLHTPALEKICSICKAMDTWLNADPHNVVVLHNKGNRGRIGVVIAAYMHYS 131
+V E GW P L + +IC+ M WL D NV V+H R V + +++ +
Sbjct: 467 NRVSECGWAARRAPHLHTLYNICRNMHAWLRQDHKNVCVVHCMDGRAASAVAVCSFLCFC 526
Query: 132 NISASADQALDRFAMKRFYEDKIVPIGQPSQRRYVHYFSGLLSGS-IKMNNKPLFLHHVI 190
+ ++A+ A+ F+MKR P PS +RY+ Y +++ I ++KP+ + V+
Sbjct: 527 RLFSTAEAAVYMFSMKR-----CPPGIWPSHKRYIEYMCDMVAEEPITPHSKPILVRAVV 581
Query: 191 MHGIPNF-ESKGGCRPFLRIYQAMQPV-YTSGIYNIPGDSQTSVCITIEP-GLLLKGDIL 247
M +P F + + GCRPF +Y + V TS Y+ D + + P G+ ++GD+L
Sbjct: 582 MTPVPLFSKQRSGCRPFCEVYVGDERVASTSQEYDKMRDFKIEDGKAVIPLGVTVQGDVL 641
Query: 248 LKCYHKKF-------RSPARDVIFRVQFHTCAI--HDLGVVFGKEDLDDAFKDDRFPEYG 298
+ YH + A +F++QFHT + + V F K DLD +++P+
Sbjct: 642 IVIYHARSTLGGRLQAKMASMKMFQIQFHTGFVPRNATTVKFAKYDLDACDIQEKYPDLF 701
Query: 299 KVEFVFSYGPEKIQGMEHLENGPSVSVDYNTSDPLI----RWDSYDNFSGHRDDGMEEVV 354
+V P + E P + +P I R + D S +
Sbjct: 702 QVNLEVEVEP---RDRPSREAPPWENSSMRGLNPKILFSSREEQQDILSKFGKPELPRQP 758
Query: 355 GHTQGPLDGSLYAKVKKKDSLHGSTGAVNATR--PTLSATPNHVEHTLSVSSDSGNSTAS 412
G T G+ + + DS + + +A+R TL T + ++ S S ++
Sbjct: 759 GSTAQYDAGAGSPEAEPTDSDSPPSSSADASRFLHTLDWQEEKEAETGAENASSKESESA 818
Query: 413 TKTDKTDEPVPGASSATAALSPQEKRELDRLLSGFGLEREKQGAMYHTQHLRSRPAGGSA 472
D+ + V + + QE R D G +Q ++ + P
Sbjct: 819 LMEDRDESEVSDEGGSPISSEGQEPR-ADPEPPGLAAGLVQQDLVFEVETPAVLP---EP 874
Query: 473 VP-SSGRHVVPAQVHVNGG-------ALASERETDILDDELPNQDGHSAGSMGTLSSLD- 523
VP G ++ V G A TD+L L + S G L S D
Sbjct: 875 VPQEDGVDLLGLHSEVGAGPAVPPQACKAPSSNTDLLSCLLGPPEAASQGPPEDLLSEDP 934
Query: 524 ----------GVTNTSEGGYPEALSPL-----TNGLDKSYPMEPMVNGGGYPYESASRAG 568
V +T GG P A P ++G + P + G +S +
Sbjct: 935 LLLASPAPPLSVQSTPRGGPPAAADPFGPLLPSSGNNSQPCSNPDLFGEFLNSDSVTVPP 994
Query: 569 PAHAGHTAPMRPSYSAQEGLAGYQREGPHPAWPQPVTTSHYAHDPSGMFRSQSFSEAEPQ 628
+ H+AP PS SA + G P P +T S D G + + + + A
Sbjct: 995 SFPSAHSAP-PPSCSAD-----FLHLGDLPGEPSKMTASSSNPDLLGGWAAWTETAASAV 1048
Query: 629 LPPAPVRGGSSREAVQRGLNSWQQQQQQQQQPRP 662
P G Q Q + Q P P
Sbjct: 1049 APTPATEGPLFSPGGQPAPCGSQASWTKSQNPDP 1082
>gi|73765544 phosphatase and tensin homolog [Homo sapiens]
Length = 403
Score = 142 bits (358), Expect = 3e-33
Identities = 89/267 (33%), Positives = 141/267 (52%), Gaps = 5/267 (1%)
Query: 5 RTMEDSCELDLVYVTERIIAVSFPSTANEENFRSNLREVAQMLKSKHGGNYLLFNL-SER 63
R ED +LDL Y+ IIA+ FP+ E +R+N+ +V + L SKH +Y ++NL +ER
Sbjct: 15 RYQEDGFDLDLTYIYPNIIAMGFPAERLEGVYRNNIDDVVRFLDSKHKNHYKIYNLCAER 74
Query: 64 RPDITKLHAKVLEFGWPDLHTPALEKICSICKAMDTWLNADPHNVVVLHNKGNRGRIGVV 123
D K + +V ++ + D + P LE I C+ +D WL+ D ++V +H K +GR GV+
Sbjct: 75 HYDTAKFNCRVAQYPFEDHNPPQLELIKPFCEDLDQWLSEDDNHVAAIHCKAGKGRTGVM 134
Query: 124 IAAYMHYSNISASADQALDRFAMKRFYEDKIVPIGQPSQRRYVHYFSGLLSGSIKMNNKP 183
I AY+ + A +ALD + R + K V I PSQRRYV+Y+S LL +
Sbjct: 135 ICAYLLHRGKFLKAQEALDFYGEVRTRDKKGVTI--PSQRRYVYYYSYLLKNHLDYRPVA 192
Query: 184 LFLHHVIMHGIPNFESKGGCRPFLRIYQAMQPVYTSGIYNIPGDSQTSVCITIEPGLLLK 243
L H ++ IP F S G C P + Q +Y+S + + +P L +
Sbjct: 193 LLFHKMMFETIPMF-SGGTCNPQFVVCQLKVKIYSSNSGPTRREDKFMYFEFPQP-LPVC 250
Query: 244 GDILLKCYHKKFRSPARDVIFRVQFHT 270
GDI ++ +HK+ + +D +F +T
Sbjct: 251 GDIKVEFFHKQNKMLKKDKMFHFWVNT 277
>gi|40549435 transmembrane phosphatase with tensin homology isoform
gamma [Homo sapiens]
Length = 513
Score = 124 bits (311), Expect = 8e-28
Identities = 90/313 (28%), Positives = 152/313 (48%), Gaps = 17/313 (5%)
Query: 5 RTMEDSCELDLVYVTERIIAVSFPSTANEENFRSNLREVAQMLKSKHGGNYLLFNL-SER 63
R D +LDL YVTERIIA+SFPS+ + +R+ ++EV + L KH +Y ++NL SER
Sbjct: 191 RYTRDGFDLDLTYVTERIIAMSFPSSGRQSFYRNPIKEVVRFLDKKHRNHYRVYNLCSER 250
Query: 64 RPDITKLHAKVLEFGWPDLHTPALEKICSICKAMDTWLNADPHNVVVLHNKGNRGRIGVV 123
D H +V+ D + P L ++ K ++ W+ D N+V +H KG R G +
Sbjct: 251 AYDPKHFHNRVVRIMIDDHNVPTLHQMVVFTKEVNEWMAQDLENIVAIHCKGGTDRTGTM 310
Query: 124 IAAYMHYSNISASADQALDRFAMKR---FYEDKIVPIGQPSQRRYVHYFSGLLSGSIKMN 180
+ A++ S I ++A ++L F +R + +K + PSQ+RYV YF+ + N
Sbjct: 311 VCAFLIASEICSTAKESLYYFGERRTDKTHSEKFQGVETPSQKRYVAYFA-QVKHLYNWN 369
Query: 181 NKP---LFLHHVIMHGIPNFESKGGCRPFLR---IYQAMQPVYTSGIYNIPGDSQTSVCI 234
P LF+ H I++ IP + + + ++ + S + NI D + I
Sbjct: 370 LPPRRILFIKHFIIYSIPRYVRDLKIQIEMEKKVVFSTISLGKCSVLDNITTD---KILI 426
Query: 235 TIEPGLLLKGDILLKCYHKKFRSPARDVIFRVQFHTCAIHDLGVVFGKEDLDDAFKDDR- 293
+ GL L D+ ++ ++ + + F HT I + + K +LD+ K
Sbjct: 427 DVFDGLPLYDDVKVQFFYSNLPTYYDNCSFYFWLHTSFIENNRLYLPKNELDNLHKQKAR 486
Query: 294 --FPEYGKVEFVF 304
+P VE +F
Sbjct: 487 RIYPSDFAVEILF 499
>gi|40549433 transmembrane phosphatase with tensin homology isoform
beta [Homo sapiens]
Length = 533
Score = 124 bits (311), Expect = 8e-28
Identities = 90/313 (28%), Positives = 152/313 (48%), Gaps = 17/313 (5%)
Query: 5 RTMEDSCELDLVYVTERIIAVSFPSTANEENFRSNLREVAQMLKSKHGGNYLLFNL-SER 63
R D +LDL YVTERIIA+SFPS+ + +R+ ++EV + L KH +Y ++NL SER
Sbjct: 211 RYTRDGFDLDLTYVTERIIAMSFPSSGRQSFYRNPIKEVVRFLDKKHRNHYRVYNLCSER 270
Query: 64 RPDITKLHAKVLEFGWPDLHTPALEKICSICKAMDTWLNADPHNVVVLHNKGNRGRIGVV 123
D H +V+ D + P L ++ K ++ W+ D N+V +H KG R G +
Sbjct: 271 AYDPKHFHNRVVRIMIDDHNVPTLHQMVVFTKEVNEWMAQDLENIVAIHCKGGTDRTGTM 330
Query: 124 IAAYMHYSNISASADQALDRFAMKR---FYEDKIVPIGQPSQRRYVHYFSGLLSGSIKMN 180
+ A++ S I ++A ++L F +R + +K + PSQ+RYV YF+ + N
Sbjct: 331 VCAFLIASEICSTAKESLYYFGERRTDKTHSEKFQGVETPSQKRYVAYFA-QVKHLYNWN 389
Query: 181 NKP---LFLHHVIMHGIPNFESKGGCRPFLR---IYQAMQPVYTSGIYNIPGDSQTSVCI 234
P LF+ H I++ IP + + + ++ + S + NI D + I
Sbjct: 390 LPPRRILFIKHFIIYSIPRYVRDLKIQIEMEKKVVFSTISLGKCSVLDNITTD---KILI 446
Query: 235 TIEPGLLLKGDILLKCYHKKFRSPARDVIFRVQFHTCAIHDLGVVFGKEDLDDAFKDDR- 293
+ GL L D+ ++ ++ + + F HT I + + K +LD+ K
Sbjct: 447 DVFDGLPLYDDVKVQFFYSNLPTYYDNCSFYFWLHTSFIENNRLYLPKNELDNLHKQKAR 506
Query: 294 --FPEYGKVEFVF 304
+P VE +F
Sbjct: 507 RIYPSDFAVEILF 519
>gi|109689707 transmembrane phosphatase with tensin homology isoform
alpha [Homo sapiens]
Length = 551
Score = 124 bits (311), Expect = 8e-28
Identities = 90/313 (28%), Positives = 152/313 (48%), Gaps = 17/313 (5%)
Query: 5 RTMEDSCELDLVYVTERIIAVSFPSTANEENFRSNLREVAQMLKSKHGGNYLLFNL-SER 63
R D +LDL YVTERIIA+SFPS+ + +R+ ++EV + L KH +Y ++NL SER
Sbjct: 229 RYTRDGFDLDLTYVTERIIAMSFPSSGRQSFYRNPIKEVVRFLDKKHRNHYRVYNLCSER 288
Query: 64 RPDITKLHAKVLEFGWPDLHTPALEKICSICKAMDTWLNADPHNVVVLHNKGNRGRIGVV 123
D H +V+ D + P L ++ K ++ W+ D N+V +H KG R G +
Sbjct: 289 AYDPKHFHNRVVRIMIDDHNVPTLHQMVVFTKEVNEWMAQDLENIVAIHCKGGTDRTGTM 348
Query: 124 IAAYMHYSNISASADQALDRFAMKR---FYEDKIVPIGQPSQRRYVHYFSGLLSGSIKMN 180
+ A++ S I ++A ++L F +R + +K + PSQ+RYV YF+ + N
Sbjct: 349 VCAFLIASEICSTAKESLYYFGERRTDKTHSEKFQGVETPSQKRYVAYFA-QVKHLYNWN 407
Query: 181 NKP---LFLHHVIMHGIPNFESKGGCRPFLR---IYQAMQPVYTSGIYNIPGDSQTSVCI 234
P LF+ H I++ IP + + + ++ + S + NI D + I
Sbjct: 408 LPPRRILFIKHFIIYSIPRYVRDLKIQIEMEKKVVFSTISLGKCSVLDNITTD---KILI 464
Query: 235 TIEPGLLLKGDILLKCYHKKFRSPARDVIFRVQFHTCAIHDLGVVFGKEDLDDAFKDDR- 293
+ GL L D+ ++ ++ + + F HT I + + K +LD+ K
Sbjct: 465 DVFDGLPLYDDVKVQFFYSNLPTYYDNCSFYFWLHTSFIENNRLYLPKNELDNLHKQKAR 524
Query: 294 --FPEYGKVEFVF 304
+P VE +F
Sbjct: 525 RIYPSDFAVEILF 537
>gi|7662146 DnaJ (Hsp40) homolog, subfamily C, member 6 [Homo
sapiens]
Length = 913
Score = 120 bits (300), Expect = 2e-26
Identities = 86/303 (28%), Positives = 147/303 (48%), Gaps = 20/303 (6%)
Query: 12 ELDLVYVTERIIAVSFPSTANEENFRSNLREVAQMLKSKHGGNYLLFNLSERRPDITKLH 71
+LD YVT RII +SFP + FR+ + ++ L S+H +Y ++NLS + K H
Sbjct: 63 DLDFTYVTSRIIVMSFPLDNVDIGFRNQVDDIRSFLDSRHLDHYTVYNLSPKSYRTAKFH 122
Query: 72 AKVLEFGWPDLHTPALEKICSICKAMDTWLNADPHNVVVLHNKGNRGRIGVVIAAYMHYS 131
++V E WP P+L + ++C+ M WL +P NV V+H R +++ A +
Sbjct: 123 SRVSECSWPIRQAPSLHNLFAVCRNMYNWLLQNPKNVCVVHCLDGRAASSILVGAMFIFC 182
Query: 132 NISASADQALDRFAMKRFYEDKIVPIG-QPSQRRYVHYFSGLLSGS-IKMNNKPLFLHHV 189
N+ ++ A+ KR IG PS RRY+ Y LL+ + + KPL + +
Sbjct: 183 NLYSTPGPAIRLLYAKR------PGIGLSPSHRRYLGYMCDLLADKPYRPHFKPLTIKSI 236
Query: 190 IMHGIPNF-ESKGGCRPFLRIYQAMQPVYT--SGIYNIPGDSQTSVCITIEPGLLLKGDI 246
+ IP F + + GCRP+ + +Y+ + + I I + ++GD+
Sbjct: 237 TVSPIPFFNKQRNGCRPYCDVLIGETKIYSTCTDFERMKEYRVQDGKIFIPLNITVQGDV 296
Query: 247 LLKCYHKKFRSPAR-------DVIFRVQFHTCAIH-DLGVV-FGKEDLDDAFKDDRFPEY 297
++ YH + +R IF++QFHT I D V+ F K +LD +++P+
Sbjct: 297 VVSMYHLRSTIGSRLQAKVTNTQIFQLQFHTGFIPLDTTVLKFTKPELDACDVPEKYPQL 356
Query: 298 GKV 300
+V
Sbjct: 357 FQV 359
>gi|213972593 TPTE and PTEN homologous inositol lipid phosphatase
isoform delta [Homo sapiens]
Length = 411
Score = 114 bits (286), Expect = 6e-25
Identities = 90/314 (28%), Positives = 150/314 (47%), Gaps = 19/314 (6%)
Query: 5 RTMEDSCELDLVYVTERIIAVSFPSTANEENFRSNLREVAQMLKSKHGGNYLLFNL-SER 63
R D +LDL YVTERIIA+SFPS+ + +R+ + EV + L KH +Y ++NL SER
Sbjct: 100 RYTRDGFDLDLTYVTERIIAMSFPSSGRQSFYRNPIEEVVRFLDKKHRNHYRVYNLCSER 159
Query: 64 RPDITKLHAKVLEFGWPDLHTPALEKICSICKAMDTWLNADPHNVVVLHNKGNRGRIGVV 123
D H +V D + P L ++ K ++ W+ D N+V +H KG +GR G +
Sbjct: 160 AYDPKHFHNRVSRIMIDDHNVPTLHEMVVFTKEVNEWMAQDLENIVAIHCKGGKGRTGTM 219
Query: 124 IAAYMHYSNISASADQALDRFAMKR---FYEDKIVPIGQPSQRRYVHYFSGLLSGSIKMN 180
+ A + S I +A+++L F +R + +K + PSQ RYV YF+ + N
Sbjct: 220 VCALLIASEIFLTAEESLYYFGERRTNKTHSNKFQGVETPSQNRYVGYFA-QVKHLYNWN 278
Query: 181 NKP---LFLHHVIMHGIPNFESKGGCRPFLRIYQAMQPVYTS---GIYNIPGDSQT-SVC 233
P LF+ I++ I C +++ + V++S G +I D +T +
Sbjct: 279 LPPRRILFIKRFIIYSIRG----DVCDLKVQVVMEKKVVFSSTSLGNCSILHDIETDKIL 334
Query: 234 ITIEPGLLLKGDILLKCYHKKFRSPARDVIFRVQFHTCAIHDLGVVFGKEDLDDAFKDDR 293
I + G L D+ ++ + + F F+T I + + + +LD+ K
Sbjct: 335 INVYDGPPLYDDVKVQFFSSNLPKYYDNCPFFFWFNTSFIQNNRLCLPRNELDNPHKQKA 394
Query: 294 ---FPEYGKVEFVF 304
+P VE +F
Sbjct: 395 WKIYPPEFAVEILF 408
>gi|213972591 TPTE and PTEN homologous inositol lipid phosphatase
isoform gamma [Homo sapiens]
Length = 522
Score = 114 bits (286), Expect = 6e-25
Identities = 90/314 (28%), Positives = 150/314 (47%), Gaps = 19/314 (6%)
Query: 5 RTMEDSCELDLVYVTERIIAVSFPSTANEENFRSNLREVAQMLKSKHGGNYLLFNL-SER 63
R D +LDL YVTERIIA+SFPS+ + +R+ + EV + L KH +Y ++NL SER
Sbjct: 211 RYTRDGFDLDLTYVTERIIAMSFPSSGRQSFYRNPIEEVVRFLDKKHRNHYRVYNLCSER 270
Query: 64 RPDITKLHAKVLEFGWPDLHTPALEKICSICKAMDTWLNADPHNVVVLHNKGNRGRIGVV 123
D H +V D + P L ++ K ++ W+ D N+V +H KG +GR G +
Sbjct: 271 AYDPKHFHNRVSRIMIDDHNVPTLHEMVVFTKEVNEWMAQDLENIVAIHCKGGKGRTGTM 330
Query: 124 IAAYMHYSNISASADQALDRFAMKR---FYEDKIVPIGQPSQRRYVHYFSGLLSGSIKMN 180
+ A + S I +A+++L F +R + +K + PSQ RYV YF+ + N
Sbjct: 331 VCALLIASEIFLTAEESLYYFGERRTNKTHSNKFQGVETPSQNRYVGYFA-QVKHLYNWN 389
Query: 181 NKP---LFLHHVIMHGIPNFESKGGCRPFLRIYQAMQPVYTS---GIYNIPGDSQT-SVC 233
P LF+ I++ I C +++ + V++S G +I D +T +
Sbjct: 390 LPPRRILFIKRFIIYSIRG----DVCDLKVQVVMEKKVVFSSTSLGNCSILHDIETDKIL 445
Query: 234 ITIEPGLLLKGDILLKCYHKKFRSPARDVIFRVQFHTCAIHDLGVVFGKEDLDDAFKDDR 293
I + G L D+ ++ + + F F+T I + + + +LD+ K
Sbjct: 446 INVYDGPPLYDDVKVQFFSSNLPKYYDNCPFFFWFNTSFIQNNRLCLPRNELDNPHKQKA 505
Query: 294 ---FPEYGKVEFVF 304
+P VE +F
Sbjct: 506 WKIYPPEFAVEILF 519
>gi|213972589 TPTE and PTEN homologous inositol lipid phosphatase
isoform alpha [Homo sapiens]
Length = 445
Score = 114 bits (286), Expect = 6e-25
Identities = 90/314 (28%), Positives = 150/314 (47%), Gaps = 19/314 (6%)
Query: 5 RTMEDSCELDLVYVTERIIAVSFPSTANEENFRSNLREVAQMLKSKHGGNYLLFNL-SER 63
R D +LDL YVTERIIA+SFPS+ + +R+ + EV + L KH +Y ++NL SER
Sbjct: 134 RYTRDGFDLDLTYVTERIIAMSFPSSGRQSFYRNPIEEVVRFLDKKHRNHYRVYNLCSER 193
Query: 64 RPDITKLHAKVLEFGWPDLHTPALEKICSICKAMDTWLNADPHNVVVLHNKGNRGRIGVV 123
D H +V D + P L ++ K ++ W+ D N+V +H KG +GR G +
Sbjct: 194 AYDPKHFHNRVSRIMIDDHNVPTLHEMVVFTKEVNEWMAQDLENIVAIHCKGGKGRTGTM 253
Query: 124 IAAYMHYSNISASADQALDRFAMKR---FYEDKIVPIGQPSQRRYVHYFSGLLSGSIKMN 180
+ A + S I +A+++L F +R + +K + PSQ RYV YF+ + N
Sbjct: 254 VCALLIASEIFLTAEESLYYFGERRTNKTHSNKFQGVETPSQNRYVGYFA-QVKHLYNWN 312
Query: 181 NKP---LFLHHVIMHGIPNFESKGGCRPFLRIYQAMQPVYTS---GIYNIPGDSQT-SVC 233
P LF+ I++ I C +++ + V++S G +I D +T +
Sbjct: 313 LPPRRILFIKRFIIYSIRG----DVCDLKVQVVMEKKVVFSSTSLGNCSILHDIETDKIL 368
Query: 234 ITIEPGLLLKGDILLKCYHKKFRSPARDVIFRVQFHTCAIHDLGVVFGKEDLDDAFKDDR 293
I + G L D+ ++ + + F F+T I + + + +LD+ K
Sbjct: 369 INVYDGPPLYDDVKVQFFSSNLPKYYDNCPFFFWFNTSFIQNNRLCLPRNELDNPHKQKA 428
Query: 294 ---FPEYGKVEFVF 304
+P VE +F
Sbjct: 429 WKIYPPEFAVEILF 442
>gi|163965366 nascent polypeptide-associated complex alpha subunit
isoform a [Homo sapiens]
Length = 2078
Score = 99.4 bits (246), Expect = 3e-20
Identities = 202/849 (23%), Positives = 290/849 (34%), Gaps = 123/849 (14%)
Query: 623 SEAEPQLPPAPVRGGSSREAVQRGLNSWQQQQQQQQQPRPPPRQQERAHLES-------L 675
S P LPPA G+ + G++ P+ P + A +
Sbjct: 733 SVPSPSLPPAGTPPGTKKVD---GISHTSALAPVASSPKECPTEDSGASATASSKGTLTY 789
Query: 676 VASRPSPQPLAETPIPSLPEFPRAASQQE------------IEQSIETLNMLMLDLE--- 720
+A PSP ++ +P P + ++ + +E S N L
Sbjct: 790 LADSPSPLGVSVSPQTKRPPTKKGSAGPDTPIGNLSSPVSPVEASFLPENSLSFQGSKDS 849
Query: 721 PASAAAPLHKSQSVPGAWPGASPLSSQPLSGSSRQSHPLTQSRSGYIPSGHSLGTPEPAP 780
PA+ +P S +PLS + ++ +++ + + G + P+ AP
Sbjct: 850 PATTHSPTPPSPKGAPTPSAVTPLSPKGVTLPPKETPTPSVVNLPFPKEGPATPAPKQAP 909
Query: 781 RASLESVPPGRSYSPYDYQPCLAGPNQDFHSKSPASSS-LPAFLPTTHSPPGPQQPPASL 839
S+ S P ++ + + A P+ PA++ P P T SP PPA+
Sbjct: 910 ALSMTSSSPKKARATPAPKGIPASPSPKGAPTPPAATPPSPKGGPATPSPKWAPTPPAAT 969
Query: 840 P----GLTAQPLLSPKEATSDPSRTPEEEPLNLEGLVAHRVAGVQAREKQPAEPPAPLRR 895
P G A P SPK A + P+ TP P G G A PP+P
Sbjct: 970 PPSPKGGPATP--SPKGAPTPPAATP---PSPKGGPATPSPKG--APTPPAVTPPSPKGS 1022
Query: 896 RAASDGQYENQSPEATSPRSPG---VRSPVQCVSPELALTIALNPGGRPKEPHLHSYKE- 951
AA+ +P A +P SP +P+ +P +P G P P L
Sbjct: 1023 PAATPFPKGASTPPAATPPSPKGSPAATPLPKGAPTTPAATLPSPKGGPATPSLKGAPTP 1082
Query: 952 --AFEEMEGTSPSSPPPSGVRSPPGLAK-TPLSALGLKPHNPADILLHPTGVTRRRIQPE 1008
A P++P P G PP +P L PH A PT T P
Sbjct: 1083 PAATPPSPKGGPATPSPKGAPMPPAATPPSPKGGLATPPHKGA-----PT--TPAATPPS 1135
Query: 1009 EDEGKVVVRLSEEPRSYVESVARTAVAGPRAQDSEPKSFSAPATQAYGHEIPLRNGTLGG 1068
G L+ P + P+ + P AP T A P G
Sbjct: 1136 PKGG-----LATPPPKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPK------G 1184
Query: 1069 SFVSPSPLST-SSPILSADSTSVGSFPSGESSDQGPR-TPTQPLLESGFRSGSLGQPSPS 1126
+PSP ++P + S P G + P+ PT P G L PSP
Sbjct: 1185 GLATPSPKGAPTTPAATPPS------PKGGLATPSPKGAPTTPAATPPSPKGGLATPSPK 1238
Query: 1127 AQRNYQSSSPLPTVGSSYSSPDYSLQHFSSSPESQARAQFSVAGVHTVPGSPQARHRTVG 1186
+++P G + P +P A S+ G P A + V
Sbjct: 1239 GAPTTPAATPPSPKGGPATPPP------KGAPTPPAATPPSLKGGLATPPHKGAPNPAVV 1292
Query: 1187 TNTPPSPGFGWRAINPSMAAPSSPSLSHHQMMGPPGTGFHGSTVSSPQSSAATTPGSPSL 1246
T PPSP G A +P AP+ P+ + G PGT + P + + G+P+L
Sbjct: 1293 T--PPSPK-GGPATSPPKGAPTPPAATPPSPKGSPGTPPPKGAPTPPAVTPPSPKGTPTL 1349
Query: 1247 CRHPAGVYQVSGLHNKVATTPGSPSLGRHPGA---HQGNLA----SGLHSNAIASP-GSP 1298
PA G TTP S P A H+G A S AI SP G P
Sbjct: 1350 ---PATTPSSKG----GPTTPSSKEGPTPPAATPSHKGGPAMTPPSPKRGPAIPSPKGDP 1402
Query: 1299 SLGRHLGGSGSVVPGSPCLDRHVA--YGGYSTPEDRRPTLSRQSSASGYQ--APSTPS-- 1352
+ + S P +P A G TP P +++ A+ P+TPS
Sbjct: 1403 TSPAVIPLSPKKAPATPVTREGAATPSKGDLTPPAVTPVSLKKAPATSAPKGGPATPSSK 1462
Query: 1353 --------FPVSPAYYPGLSSPATSPSPDSAAFR---QGSPT------------PALPEK 1389
P SP P ATS SP A G+PT PA P
Sbjct: 1463 GDPTLPAVTPPSPKEPPAPKQVATSSSPKKAPATPAPMGAPTLPAVIPSSPKEVPATPSS 1522
Query: 1390 RRMSVGDRA 1398
RR + A
Sbjct: 1523 RRDPIAPTA 1531
Score = 87.0 bits (214), Expect = 1e-16
Identities = 202/810 (24%), Positives = 279/810 (34%), Gaps = 206/810 (25%)
Query: 672 LESLVASRPSPQPLAETPIPSLPEFPRAASQQEIEQSIETLNMLMLDLEPASAAAPLHKS 731
LE V+ P P+ E + +LP P A+ + S + L A + KS
Sbjct: 677 LEGTVSLAPKNHPVKEGTLTTLPLVPTASENCPVAPSPQNT---CAPLATLVLAPEIPKS 733
Query: 732 QSVPGAWPGASPLSSQPLSGSSRQSH--PLTQSRSGYIPSGHSLGTPEPAPRASLESV-- 787
P P +P ++ + G S S P+ S P+ S + + + +L +
Sbjct: 734 VPSPSLPPAGTPPGTKKVDGISHTSALAPVASSPKE-CPTEDSGASATASSKGTLTYLAD 792
Query: 788 ---PPGRSYSPYDYQPCL----AGPNQDFHS-KSPASSSLPAFLP--------------T 825
P G S SP +P AGP+ + SP S +FLP T
Sbjct: 793 SPSPLGVSVSPQTKRPPTKKGSAGPDTPIGNLSSPVSPVEASFLPENSLSFQGSKDSPAT 852
Query: 826 THSPPGPQQPPASLPGLTAQPLLSPKEATSDPSRTPEEEPLNL----EGLV------AHR 875
THSP P P P +A LSPK T P TP +NL EG A
Sbjct: 853 THSPTPPS--PKGAPTPSAVTPLSPKGVTLPPKETPTPSVVNLPFPKEGPATPAPKQAPA 910
Query: 876 VAGVQAREKQPAEPPAPLRRRAASDGQYENQSPEATSPRSP--GVRSPVQCVSPELALTI 933
++ + K+ PAP + AS +P A +P SP G +P SP+ A T
Sbjct: 911 LSMTSSSPKKARATPAP-KGIPASPSPKGAPTPPAATPPSPKGGPATP----SPKWAPT- 964
Query: 934 ALNPGGRPKEPHLHSYKEAFEEMEGTSPSSPPPSGVRSPPGLAKTPLSALGLKPHNPADI 993
P P P P++P P G +PP A TP S G P P+
Sbjct: 965 --PPAATPPSPK-------------GGPATPSPKGAPTPP--AATPPSPKG-GPATPS-- 1004
Query: 994 LLHPTGV-TRRRIQPEEDEGKVVVRLSEEPRSYVESVARTAVAGPRAQDSEPKSFSAPAT 1052
P G T + P +G + A P A PK
Sbjct: 1005 ---PKGAPTPPAVTPPSPKGSPAAT----------PFPKGASTPPAATPPSPKG------ 1045
Query: 1053 QAYGHEIPLRNGTLGGSFVSPSPLSTSSPILSADSTSVGSFPSGESSDQGPRTPTQPLLE 1112
SP +T P A +T + PS + GP TP+
Sbjct: 1046 ---------------------SPAATPLP-KGAPTTPAATLPSPKG---GPATPSLK--- 1077
Query: 1113 SGFRSGSLGQPSPSAQRNYQSSSPLPTVGSSYSSPDYSLQHFSSSPESQARAQFSVAGVH 1172
G P+P A ++ P P G + SP + +++P S G+
Sbjct: 1078 --------GAPTPPA-----ATPPSPKGGPATPSPKGAPMPPAATPPSPK------GGLA 1118
Query: 1173 TVP--GSPQARHRTVGTNTPPSPGFGWRAINPSMAAPSSPSLSHHQMMGPPGTGFHGSTV 1230
T P G+P T TPPSP G A P AP++P+ + PP G
Sbjct: 1119 TPPHKGAP-----TTPAATPPSPK-GGLATPPPKGAPTTPAAT------PPSP--KGGLA 1164
Query: 1231 SSPQSSAATTPGSPSLCRHPAGVYQVSGLHNKVATTPGSPSLGRHPGAHQGNLAS----G 1286
+ P A TTP A TP SP +G LA+ G
Sbjct: 1165 TPPPKGAPTTP----------------------AATPPSP---------KGGLATPSPKG 1193
Query: 1287 LHSNAIASPGSPSLGRHLGGSGSVVPGSPCLDRHVAYGGYSTPEDR-RPTLSRQSSASGY 1345
+ A+P SP G S P +P GG +TP + PT + S
Sbjct: 1194 APTTPAATPPSPK-GGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPK 1252
Query: 1346 QAPSTP---SFPVSPAYYP-----GLSSPATSPSPDSAAFRQGSPTPALPEKRRMSVGDR 1397
P+TP P PA P GL++P +P+ A TP P+ + +
Sbjct: 1253 GGPATPPPKGAPTPPAATPPSLKGGLATPPHKGAPNPAVV-----TPPSPKGGPATSPPK 1307
Query: 1398 AGSLPNYATINGKVSSPVASGMSSPSGGST 1427
P AT SP G P G T
Sbjct: 1308 GAPTPPAATPPSPKGSP---GTPPPKGAPT 1334
Score = 79.7 bits (195), Expect = 2e-14
Identities = 206/830 (24%), Positives = 275/830 (33%), Gaps = 115/830 (13%)
Query: 680 PSPQPLAETPIPSLPEFPRAASQQEIEQSIETLNMLMLDLEPASAAAPLHKSQSVPGAWP 739
P P+ L P L +FP Q + S+E PA A K +V
Sbjct: 510 PDPEDLKNLPSSVLVKFPTQKDLQTVPASLEG-----APFSPAQAGLTTKKDPTVLPLVQ 564
Query: 740 GASPLSSQPLSGSSRQSHPLTQSRSGYIPSGHSLGTPEP--APRASLESVPPGRSYSPYD 797
A S S SS PL+ + + SLG P P P +S+ S S +
Sbjct: 565 AAPKNSPSFQSTSSSPEIPLSPEAT---LAKKSLGEPLPIGKPASSMTSPLGVNSSASVI 621
Query: 798 YQPCLAGPNQDFHSKSPASSSLPAFLPTTHSPPGPQQPPASLPGLTAQPLLSPKEATSDP 857
AGP+ S P S PT + P PA + TA+ S T+ P
Sbjct: 622 KTDSYAGPD----SAGPLLKS-SLITPTVAAFPLESADPAGVAPTTAKG-TSTYTTTASP 675
Query: 858 ------SRTPEEEPLNLEGLVAHRVAGVQAREKQPAEPPAPLRRRAASDGQYENQSPEAT 911
S P+ P+ EG + A E P P + + P++
Sbjct: 676 FLEGTVSLAPKNHPVK-EGTLTTLPLVPTASENCPVAPSPQNTCAPLATLVLAPEIPKSV 734
Query: 912 -SPRSPGVRSPVQCVSPE-LALTIALNP-GGRPKE-PHLHSYKEAFEEMEGT---SPSSP 964
SP P +P + ++ T AL P PKE P S A +GT SP
Sbjct: 735 PSPSLPPAGTPPGTKKVDGISHTSALAPVASSPKECPTEDSGASATASSKGTLTYLADSP 794
Query: 965 PPSGVRSPPGLAKTPLSALGLKPHNPADILLHPTGVTRRRIQPEE------DEGKVVVRL 1018
P GV P + P P P L P PE +
Sbjct: 795 SPLGVSVSPQTKRPPTKKGSAGPDTPIGNLSSPVSPVEASFLPENSLSFQGSKDSPATTH 854
Query: 1019 SEEPRSYVESVARTAVA--GPRAQDSEPKSFSAPATQAYGHEIPLRNGTLGGSFVSPSPL 1076
S P S + +AV P+ PK P P +P+
Sbjct: 855 SPTPPSPKGAPTPSAVTPLSPKGVTLPPK--ETPTPSVVNLPFPKEGPATPAPKQAPALS 912
Query: 1077 STSSPILSADSTSVGSFPSGESSDQGPR-TPTQPLLESGFRSGSLGQPSPS-AQRNYQSS 1134
TSS A +T P G + P+ PT P G PSP A ++
Sbjct: 913 MTSSSPKKARATPA---PKGIPASPSPKGAPTPPAATPPSPKGGPATPSPKWAPTPPAAT 969
Query: 1135 SPLPTVGSSYSSPDYSLQHFSSSPESQ--ARAQFSVAGVHTVP--------GSPQARHRT 1184
P P G + SP + +++P S A S G T P GSP A
Sbjct: 970 PPSPKGGPATPSPKGAPTPPAATPPSPKGGPATPSPKGAPTPPAVTPPSPKGSPAATPFP 1029
Query: 1185 VGTN-----TPPSPGFGWRAINPSMAAPSSPSLSHHQMMGPPGTGFHGSTVSSPQSSAAT 1239
G + TPPSP A AP++P+ + G P T S +P AAT
Sbjct: 1030 KGASTPPAATPPSPKGSPAATPLPKGAPTTPAATLPSPKGGPAT---PSLKGAPTPPAAT 1086
Query: 1240 TPGSPSLCRHPAGVYQVSGLHNKVATTPGSPSLG----RHPGA----------HQGNLAS 1285
P P+ G A TP SP G H GA +G LA+
Sbjct: 1087 PPSPKGGPATPS----PKGAPMPPAATPPSPKGGLATPPHKGAPTTPAATPPSPKGGLAT 1142
Query: 1286 ----GLHSNAIASPGSPSLGRHLGGSGSVVPGSPCLDRHVAYGGYSTPEDR----RPTLS 1337
G + A+P SP G P +P GG +TP + P +
Sbjct: 1143 PPPKGAPTTPAATPPSPK-GGLATPPPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAAT 1201
Query: 1338 RQSSASGYQAPSTPSFPVSPAYYP-----GLSSP----------ATSPSPDSAAFR---Q 1379
S G PS P +PA P GL++P AT PSP +
Sbjct: 1202 PPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGPATPPPK 1261
Query: 1380 GSPTPALPEKRRMSVGDRAGSLPNYATINGKVSSPVASGMSSPSGGSTVS 1429
G+PTP P S+ + P+ N V +P SP GG S
Sbjct: 1262 GAPTP--PAATPPSLKGGLATPPHKGAPNPAVVTP-----PSPKGGPATS 1304
Score = 69.7 bits (169), Expect = 2e-11
Identities = 199/805 (24%), Positives = 279/805 (34%), Gaps = 127/805 (15%)
Query: 677 ASRPSPQPLAETPIPSLPEFPRAASQQEIEQSIETLNMLMLDLEPASAAAPLHKSQSVPG 736
A+ P P+ TP +LP P+ + T A P K +P
Sbjct: 1048 AATPLPKGAPTTPAATLPS-PKGGPATPSLKGAPTPPAATPPSPKGGPATPSPKGAPMP- 1105
Query: 737 AWPGASPLSSQPLSGSSRQSH---PLTQSRSGYIPSGHSLGTPEPAPRASLESVPPGRSY 793
P A+P S P G + H P T + + P G L TP P + P +
Sbjct: 1106 --PAATPPS--PKGGLATPPHKGAPTTPAATPPSPKG-GLATPPP------KGAPTTPAA 1154
Query: 794 SPYDYQPCLAGPNQDFHSKSPASSS-LPAFLPTTHSPPGPQQPPASLP----GLTAQPLL 848
+P + LA P +PA++ P T SP G PA+ P G A P
Sbjct: 1155 TPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATP-- 1212
Query: 849 SPKEATSDPSRTPEEEPLNLEGLVAHRVAGVQAREKQPAEPPAPLRRRAASDGQYENQSP 908
SPK A + P+ TP P GL G A A PP+P A + P
Sbjct: 1213 SPKGAPTTPAATP---PSPKGGLATPSPKG--APTTPAATPPSPKGGPATPPPKGAPTPP 1267
Query: 909 EATSPR-SPGVRSPVQCVSPELALTIALNPGGRPKEPH---LHSYKEAFEEMEGTSPSSP 964
AT P G+ +P +P A+ +P G P + A SP +P
Sbjct: 1268 AATPPSLKGGLATPPHKGAPNPAVVTPPSPKGGPATSPPKGAPTPPAATPPSPKGSPGTP 1327
Query: 965 PPSGVRSPPGL------------AKTPLSALGLK-------PHNPADILLHPTGVTRRRI 1005
PP G +PP + A TP S G P PA H G
Sbjct: 1328 PPKGAPTPPAVTPPSPKGTPTLPATTPSSKGGPTTPSSKEGPTPPAATPSHKGGPAMTPP 1387
Query: 1006 QPE----------EDEGKVVVRLSEEPRSYVESVARTAVAGPRAQDSEPKSFS------A 1049
P+ + V+ LS + ++ V R A P D P + + A
Sbjct: 1388 SPKRGPAIPSPKGDPTSPAVIPLSPK-KAPATPVTREGAATPSKGDLTPPAVTPVSLKKA 1446
Query: 1050 PATQAY--GHEIPLRNG--TLGGSFVSPSPLSTSSPILSADSTSVGSFPSG--------- 1096
PAT A G P G TL + PSP +P A S+S P+
Sbjct: 1447 PATSAPKGGPATPSSKGDPTLP-AVTPPSPKEPPAPKQVATSSSPKKAPATPAPMGAPTL 1505
Query: 1097 -----ESSDQGPRTPTQPLLESGFRSGSLGQPSPSAQRNYQSS-SPLPTVGSSYSSPDYS 1150
S + P TP+ + L + +P+ ++ P TV S +P
Sbjct: 1506 PAVIPSSPKEVPATPSSRRDPIAPTATLLSKKTPATLAPKEALIPPAMTVPSPKKTPAIP 1565
Query: 1151 L-QHFSSSPESQARAQFSVAGVHTVPGSPQARHRTVGTN-TPPSPGFGWRAINPSMAAPS 1208
+ ++P S+ + T G+P + + T PSP A P P
Sbjct: 1566 TPKEAPATPSSKEASSPPAVTPSTYKGAPSPKELLIPPAVTSPSPK---EAPTPPAVTPP 1622
Query: 1209 SPSLSHHQMMGPPGTGFHGSTVSSP--QSSAATTPGSPS--LCRHPAGVYQVS-GLHNK- 1262
SP GP G+ S P SS +P SP+ C+ A V Q S GL K
Sbjct: 1623 SPE------KGPATPAPKGTPTSPPVTPSSLKDSPTSPASVTCKMGATVPQASKGLPAKK 1676
Query: 1263 ---------VATTPGSPSLGRHPGAHQGNLASGLHSNAIASPGSPSLGRHLGGSG--SVV 1311
VA P S + P +G S+A + P P G G S V
Sbjct: 1677 GPTALKEVLVAPAPESTPIITAP-TRKGPQTK--KSSATSPPICPDPSAKNGSKGPLSTV 1733
Query: 1312 PGSPCL-----DRHVAYGGYSTPEDRRPTLSRQSSASGYQAPSTPSFPVSPAYYPGLSSP 1366
+P L A G ++ + P +S AS P T + P +S
Sbjct: 1734 APAPLLPVQKDSSKTAKGKDASHSPKGPLAPPESKAS---TPLTAAAFEKVLPKPESASV 1790
Query: 1367 ATSPSPDSAAFRQGSPTPALPEKRR 1391
+ +PSP + SP P LP K++
Sbjct: 1791 SAAPSPPVSLPLAPSPVPTLPPKQQ 1815
Score = 49.3 bits (116), Expect = 3e-05
Identities = 178/833 (21%), Positives = 271/833 (32%), Gaps = 148/833 (17%)
Query: 390 SATPNHVEHTLSVSSDSGNSTASTKTDKTDE------PVPGASSATAALSPQEKRELDRL 443
+ATP + L+ G T T + + P GA + AA P K L
Sbjct: 1107 AATPPSPKGGLATPPHKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGL--- 1163
Query: 444 LSGFGLEREKQGAMYHTQHLRSRPAGGSAVPS-SGRHVVPAQVHVNG-GALASERETDIL 501
+GA P GG A PS G PA + G LA+
Sbjct: 1164 -----ATPPPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLAT------- 1211
Query: 502 DDELPNQDGHSAGSMGTLSSLDGVTNTSEGGYPEALSPLTNGLDKSYPMEPMVNGGGYPY 561
P+ G T S G T T K P P G P
Sbjct: 1212 ----PSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGPATPPPKGAPTPP 1267
Query: 562 ESAS---RAGPAHAGHTAPMRPSYSAQEGLAGYQREGPHPAWPQPVTTSHYAHDPSGMFR 618
+ + G A H P+ G P P P + + S
Sbjct: 1268 AATPPSLKGGLATPPHKGAPNPAVVTPPSPKGGPATSPPKGAPTPPAATPPSPKGSPGTP 1327
Query: 619 SQSFSEAEPQLPPAPVRGGSSREAVQRGLNSWQQQQQQQQQPRPPPRQQERAHLESLVAS 678
+ P + P +G + A ++ P PP +H +
Sbjct: 1328 PPKGAPTPPAVTPPSPKGTPTLPATTPSSKGGPTTPSSKEGPTPPAATP--SHKGGPAMT 1385
Query: 679 RPSPQPLAETPIPS--------LPEFPR-----------AASQQEIEQSIETLNMLMLDL 719
PSP+ P P +P P+ AA+ + + + + + L
Sbjct: 1386 PPSPKRGPAIPSPKGDPTSPAVIPLSPKKAPATPVTREGAATPSKGDLTPPAVTPVSLKK 1445
Query: 720 EPASAA------APLHKSQ----SVPGAWPGASPLSSQPLSGSSRQSHPLTQSRSGYIPS 769
PA++A P K +V P P Q + SS + P T + G
Sbjct: 1446 APATSAPKGGPATPSSKGDPTLPAVTPPSPKEPPAPKQVATSSSPKKAPATPAPMG---- 1501
Query: 770 GHSLGTPEPAPRASLESVPPGRSYSPYDYQPCLAGPNQDFHSKSPAS-SSLPAFLPTTHS 828
P A + S P +P + +A K+PA+ + A +P +
Sbjct: 1502 -------APTLPAVIPSSPKEVPATPSSRRDPIAPTATLLSKKTPATLAPKEALIPPAMT 1554
Query: 829 PPGPQQPPASLPGLTAQPLLSPKEATSDPSRTP---EEEPLNLEGLVAHRVAGVQARE-- 883
P P++ PA A S KEA+S P+ TP + P E L+ V +E
Sbjct: 1555 VPSPKKTPAIPTPKEAPATPSSKEASSPPAVTPSTYKGAPSPKELLIPPAVTSPSPKEAP 1614
Query: 884 KQPA-EPPAPLRRRAASDGQYENQSPEAT------SPRSPGVRSPVQCVSPELALTIALN 936
PA PP+P + A + SP T SP SP V+ ++ T+
Sbjct: 1615 TPPAVTPPSPEKGPATPAPKGTPTSPPVTPSSLKDSPTSPA------SVTCKMGATVPQA 1668
Query: 937 PGGRPKEPHLHSYKEAF------------------EEMEGTSPSSPPPSGVRSPPGLAKT 978
G P + + KE + + +S +SPP S +K
Sbjct: 1669 SKGLPAKKGPTALKEVLVAPAPESTPIITAPTRKGPQTKKSSATSPPICPDPSAKNGSKG 1728
Query: 979 PLSALGLKPHNPADILLHPTGVTRRRIQPEEDEGKVVVRLSEEPRSYVESVARTAVAGPR 1038
PLS + P P ++ + +GK + P + ES A T +
Sbjct: 1729 PLSTVAPAPLLPV-----------QKDSSKTAKGKDASHSPKGPLAPPESKASTPLTAAA 1777
Query: 1039 AQDSEPKSFSAPATQAYGHEIPLRNGTLGGSFVSPSPLST---------SSPILSADSTS 1089
+ PK SA + A + L ++PSP+ T SSP L +S S
Sbjct: 1778 FEKVLPKPESASVSAAPSPPVSLP--------LAPSPVPTLPPKQQFLPSSPGLVLESPS 1829
Query: 1090 VGSFPSGESSDQGPRTPTQPLLESG---FRSGSLGQPSPSAQRNYQSSSPLPT 1139
P+ E + P P +P+ SG F+S + P+P + + P+PT
Sbjct: 1830 KPLAPADE-DELLPLIPPEPI--SGGVPFQSVLVNMPTPKS-----AGIPVPT 1874
Score = 45.1 bits (105), Expect = 6e-04
Identities = 191/794 (24%), Positives = 271/794 (34%), Gaps = 178/794 (22%)
Query: 752 SSRQSHPLTQSRSGYIPSGHSLGTP----EPAPRASLESVPPGRSYSPYDYQPC-LAGPN 806
++ Q P Q+ + +P +L +P P ++PP S +P Q C L+ N
Sbjct: 11 ATEQELPQPQAETAVLPMSSALSVTAALGQPGP-----TLPPPCSPAP---QQCPLSAAN 62
Query: 807 QDFHSKSPAS-SSLPAFLPTTHSPPGPQQP-------PASLPGLTAQPLLSPKEATSDPS 858
Q SP++ +S P +P S G P P LP L P+ A + P
Sbjct: 63 QASPFPSPSTIASTPLEVPFPQSSSGTALPLGTAPEAPTFLPNLIGPPISPAALALASPM 122
Query: 859 RTP-------EEEPLNLEGLVAHRVAGVQAREKQPAEPPAPLRRRAASDGQYENQSPEAT 911
P PL L L H V +K A PP L T
Sbjct: 123 IAPTLKGTPSSSAPLALVALAPHSV------QKSSAFPPNLL-----------------T 159
Query: 912 SPRSPGVRSPVQCVSPELALTIALNPGGRPKEPHLHSYKEAFEEMEGTSPSSPPPSGVRS 971
SP S V E I L+ P EP + K E + + PP V +
Sbjct: 160 SPPSVAVA--------ESGSVITLSAPIAPSEPKTNLNKVPSEVVPNPKGTPSPPCIVST 211
Query: 972 PPGLAKTPLSAL-----GLKPHNPADIL------LHPTGVTRRRIQPEED-----EGKV- 1014
P TP++++ L P L + T ++ I P+ +G V
Sbjct: 212 VPYHCVTPMASIQSGVASLPQTTPTTTLAIASPQVKDTTISSVLISPQNPGSLSLKGPVS 271
Query: 1015 ---VVRLSEEPRSYVESVARTAVAGPRAQDSEPKSFSAPATQAYGHEIPLRNGTLGG--- 1068
+ LS + V S +T AGP P S + H PL + G
Sbjct: 272 PPAALSLSTQSLPVVTSSQKT--AGPNTPPDFPISLGS-------HLAPLHQSSFGSVQL 322
Query: 1069 -SFVSPSPLSTSS-PILSADSTSVG-SFPSGES--SDQGPRTPTQPLLESGFRSGSLGQP 1123
PS LS + +S D +S G S+PS S R P + F
Sbjct: 323 LGQTGPSALSDPTVKTISVDHSSTGASYPSQRSVIPPLPSRNEVVPATVAAF-----PVV 377
Query: 1124 SPSAQRNYQSSSPLPTVGSSYSSPDYSLQ---HFSSSPESQARAQFSVAGVHTVPGSPQA 1180
+PS + T+ S SP SL FS SP + + S + P Q
Sbjct: 378 APSVDKGPS------TISSITCSPSGSLNVATSFSLSPTTSLILKSSPNATYHYPLVAQM 431
Query: 1181 RHRTVGTNTPPSPGFGWRAINPSMAAPSSPSLSHHQMMGPPGTGFHGST-VSSPQSSAAT 1239
+VGT TP NP A + P T F +T VS P SS
Sbjct: 432 PVSSVGT-TP------LVVTNPCTIAAA------------PTTTFEVATCVSPPMSSGPI 472
Query: 1240 T---PGSP-SLCRHPAGVYQVSGLHNKVATT---PGSPSLGRHPGAHQ-GNLASGLHSNA 1291
+ P SP +L P + S +VATT P SP L P NL S +
Sbjct: 473 SNIEPTSPAALVMAPVAPKEPS---TQVATTLRIPVSPPL---PDPEDLKNLPSSVLVKF 526
Query: 1292 IASPGSPSLGRHLGGSGSVVPGSPCLDRHVAYGGYSTPEDRRPTLSRQSSASGYQAPSTP 1351
++ L G+ P SP A G +T +D PT+ A AP
Sbjct: 527 PTQKDLQTVPASLEGA----PFSP------AQAGLTTKKD--PTVLPLVQA----APKN- 569
Query: 1352 SFPVSPAYYPGLSSPATSPSPDSAAFRQ--GSPTPALPEKRRMSVGDRAGSLPNYATING 1409
SP++ SSP SP++ ++ G P P +G A S+ + +N
Sbjct: 570 ----SPSFQSTSSSPEIPLSPEATLAKKSLGEPLP---------IGKPASSMTSPLGVNS 616
Query: 1410 KVSSPVASGMSSP-SGGSTVSFSHTLPDFSKYSMPDNSPETRAKVKFVQDTSKYWYKPEI 1468
S + P S G + S P + + + P A + TS Y
Sbjct: 617 SASVIKTDSYAGPDSAGPLLKSSLITPTVAAFPLESADPAGVAPTT-AKGTSTYTTTASP 675
Query: 1469 SREQAIALLKDQEP 1482
E ++L P
Sbjct: 676 FLEGTVSLAPKNHP 689
>gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapiens]
Length = 855
Score = 87.4 bits (215), Expect = 1e-16
Identities = 197/842 (23%), Positives = 270/842 (32%), Gaps = 189/842 (22%)
Query: 556 GGGYPYESASRAGPAHAGHTAPMRPSYSAQEGLAGYQREGPHPAWPQPVTTSHYAHDPSG 615
GG ESA RAGP + T+ P+ G + P PV++ A SG
Sbjct: 66 GGATIPESAPRAGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRA---SG 122
Query: 616 MFRSQSFSEAEPQLPPAP-VRGGSSREAVQRG-LNSWQQQQQQQQQP-RPPPRQQERAHL 672
R + ++ V G + EA +R L++ ++ P P P R+
Sbjct: 123 TTRPGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRA 182
Query: 673 ESLVASRPSPQPLAETPIPSLPEFPRAASQQEIEQSIE-------------------TLN 713
P P P A P+ E PR + E S
Sbjct: 183 AGTEVGLPRPAPSARPRPPT--EGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASR 240
Query: 714 MLMLDLEPASAAA------------PLHKSQSVP----------------GAWPGASPLS 745
L P S+ A P H SQ P A P PLS
Sbjct: 241 SLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLS 300
Query: 746 SQPLSGSSRQSHPLTQSRSGYIPSGHS------LGTPEPAPRASLESVPPGRSYSPYDYQ 799
S PL+ S + +Q+ + HS L TP P S S PP P
Sbjct: 301 SSPLATPSPSAALQSQAPPTLPATPHSSSLTCQLATPLPLAPPS-PSAPPSLQTLP---S 356
Query: 800 PCLAGPNQDFHSK-SPASSSLPAFLPTTHSPPGPQQPPASLPGLTAQPLLSPKEATSDPS 858
P P+Q S SP + +FLP+ P PP + P L PL +P + P
Sbjct: 357 PPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPPASPP 416
Query: 859 RTPEEEPLNLEGLVAHRVAGVQAREKQPAEPP--APLRRRAASDGQYENQSPEATSPRSP 916
+P P + + A V +QA P PP AP SP A+ P SP
Sbjct: 417 LSPLATP-SPQAPNALAVHLLQAPFSPPPSPPVQAPF-------------SPPASPPVSP 462
Query: 917 GVRSPVQCVSPELALTIALNPGGRPKEPHLHSYKEAFEEMEGTSPSSPPPSGVRSPPGLA 976
P Q P LA P P P + SPS+ PP ++PP LA
Sbjct: 463 SATPPSQ-APPSLAAPPLQVPPSPPASPPM-------------SPSATPPP--QAPPPLA 506
Query: 977 KTPLSALGLKPHNPADILLHPTGVTRRRIQPEEDEGKVVVRLSEEPRSYVESVARTAVAG 1036
PL P P + P
Sbjct: 507 APPLQLAKPPPQAPPALATPPL-------------------------------------- 528
Query: 1037 PRAQDSEPKSFSAPATQAYGHEIPLRNGTLGGSFVSPSPLST----SSPILSADSTSVGS 1092
+A S P SF A + +P+ SPL+T + P+L+A V
Sbjct: 529 -QALPSPPASFPGQAPFSPSASLPM------------SPLATPPPQAPPVLAAPLLQVPP 575
Query: 1093 FPSGESSDQGPRTPTQPLLESGFRSGSL-------GQPSPSAQRNYQSSSP-LPTVGSSY 1144
P + Q PR P P ++ L P PS + S P L SS
Sbjct: 576 SPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSA 635
Query: 1145 SSPDYSLQHFSSSPESQARA----QFSVAGVHTV-----PGSPQARHRTVGTNTPPSPGF 1195
+S L+ + S PE A A +A H P P A G P P
Sbjct: 636 TSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAWSRGPAPPLAFRGAPGAPLPWPPAT 695
Query: 1196 G----------WRAINPSMAAPSSPSLSHHQMMGP-PGTGFHGSTVSSPQSSAATTPGSP 1244
G + P A P+ +L GP PGT + + +++ +P
Sbjct: 696 GPGSADGLCTIYETEGPESATPAPGALD----PGPSPGTSGGKAAAGAGAGASSRSPKQA 751
Query: 1245 SLCRHPAGVYQVSGLHNKVATT----PGSPSLGRHPGAHQGNLASGLHSNAIASPGSPSL 1300
L P G Q S + + ++ T + G G G G+ A A+ L
Sbjct: 752 RLGELPLGALQASVVQHLLSRTLLLAAAEGAAGGSGGGPGGAEGGGVTGGARAALSDAEL 811
Query: 1301 GR 1302
GR
Sbjct: 812 GR 813
Score = 57.0 bits (136), Expect = 2e-07
Identities = 133/587 (22%), Positives = 199/587 (33%), Gaps = 117/587 (19%)
Query: 906 QSPEATSPRSPGVRSPVQCVSPELALTIALNPGGRPKEPHLHSYKEAFEEMEGTSPSSPP 965
++P +PR PG P V+P AL + G ++P + A T P S P
Sbjct: 20 RAPGLLTPRPPGSPRPPPPVTPA-ALRVLGAAGAVGRKPLA---ERAGGIGGATIPESAP 75
Query: 966 PSGVRSPPGLAKTPLSALGLKPHNPADILLHPTGVTRRRIQPEEDEGKVVVRLSEEPRSY 1025
+G P + G NPA P R P ++ S P S
Sbjct: 76 RAG----------PTRSAGTSSRNPAS--RPPASGRGERAPPAKNT-------SPGPVSS 116
Query: 1026 VESVARTAVAGPRAQDSEPKSFSAPATQAYGHEIPLRNGTLGGS---FVSPSPLSTSSPI 1082
+ T GP Q S + E P R+ G+ P+P T SP
Sbjct: 117 PGRASGTTRPGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTP-GTPSPA 175
Query: 1083 LSADSTSVGS---FPSGESSDQGPRTPTQPLLESGFRSG--SLGQPSPSAQRNYQSSSPL 1137
++ S + G+ P S + PR PT+ +S + S +PSP+A+R
Sbjct: 176 MARRSRAAGTEVGLPRPAPSAR-PRPPTEGPRKSVSSASEHSTTEPSPAARRR------- 227
Query: 1138 PTVGSSYSSPDYSLQHFSSSP-ESQARAQFSVAGVHTVPGSP-QARHRTVGTNTPP---- 1191
P+ G P S++P S AR+ S G P P Q + + + PP
Sbjct: 228 PSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTP 287
Query: 1192 -----SPGFGWRAINP-----------SMAAPSSPSLSHHQMM----------------G 1219
+P G + +P S A P+ P+ H +
Sbjct: 288 PRKDAAPALGPLSSSPLATPSPSAALQSQAPPTLPATPHSSSLTCQLATPLPLAPPSPSA 347
Query: 1220 PPGTGFHGSTVSSPQSSAATTPGSPSLCRHPAGVYQVSGLHNKVATTPGSPSLGRHPGAH 1279
PP S ++P S A T+ GSP+L H+ + + P SP P A
Sbjct: 348 PPSLQTLPSPPATPPSQATTSLGSPTL----------QATHSFLPSPPLSPLATPPPQA- 396
Query: 1280 QGNLASGLHSNAIASPGSPSLGRHLGGSGSVVPGSP-CLDRHVAYGGYSTPED------- 1331
L + +P SP L + P +P L H+ +S P
Sbjct: 397 ----PPALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPF 452
Query: 1332 ---RRPTLSRQSSASGYQAPST--------PSFPVSPAYYPGLSSPATSPSPDSA----- 1375
P +S ++ PS PS P SP P + P +P P +A
Sbjct: 453 SPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQL 512
Query: 1376 AFRQGSPTPALPEKRRMSVGDRAGSLPNYATINGKVSSPVASGMSSP 1422
A PAL ++ S P A + S P++ + P
Sbjct: 513 AKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPP 559
Score = 48.1 bits (113), Expect = 7e-05
Identities = 83/375 (22%), Positives = 140/375 (37%), Gaps = 56/375 (14%)
Query: 1108 QPLLESGFRSGSLGQPSPSAQRNYQSSSPLPTVGSSYSSPDYSLQHFSSSPESQARAQFS 1167
+PL E R+G +G + + + P + G+S +P +S P + R + +
Sbjct: 56 KPLAE---RAGGIG--GATIPESAPRAGPTRSAGTSSRNP-------ASRPPASGRGERA 103
Query: 1168 VAGVHTVPGSPQARHRTVGTNTPPSPGFGWRAINPSMAAPSSPSLSHHQMMGPPGTGFHG 1227
+T PG + R GT P G + + +++ + P
Sbjct: 104 PPAKNTSPGPVSSPGRASGTTRPGPLG------QKGLRISAEETVARGKATEAPKRS--A 155
Query: 1228 STVSSPQSSAATTPGSPSLCRHPAGVYQVSGLHNKVATTPGSPSLGRHP---GAHQGNLA 1284
+ + + ++ TPG+PS PA + +V +PS P G + +
Sbjct: 156 LSAGARRDTSGPTPGTPS----PAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSS 211
Query: 1285 SGLHSNAIASPGS---PSLGRHLG--GSGSVVPGSPCLDRHVAYGGYSTPEDRRPTLSRQ 1339
+ HS SP + PS G L S S+ + L G + R P Q
Sbjct: 212 ASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQ 271
Query: 1340 SSASGYQAPSTPSFP-----VSPAYYPGLSSPATSPSPDSAAFRQGSPTPALPEKRRMSV 1394
G QA P +PA P SSP +PSP +A Q PT LP
Sbjct: 272 PKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAALQSQAPPT--LP------- 322
Query: 1395 GDRAGSLPNYATINGKVSSPVASGMSSPSGGSTVSFSHTLPDFSKYSMPDNSPETRAKVK 1454
+ P+ +++ ++++P+ SPS ++ TLP S + P + T
Sbjct: 323 -----ATPHSSSLTCQLATPLPLAPPSPSAPPSL---QTLP--SPPATPPSQATTSLGSP 372
Query: 1455 FVQDTSKYWYKPEIS 1469
+Q T + P +S
Sbjct: 373 TLQATHSFLPSPPLS 387
>gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapiens]
Length = 1124
Score = 87.4 bits (215), Expect = 1e-16
Identities = 234/973 (24%), Positives = 334/973 (34%), Gaps = 139/973 (14%)
Query: 556 GGGYPYESASRAGPAHAGHTAPMRPSYSAQEGLAGYQREGPHPAWPQPVTTSHYAHDPSG 615
GG ESA RAGP + T+ P+ G + P PV++ A SG
Sbjct: 66 GGATIPESAPRAGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRA---SG 122
Query: 616 MFRSQSFSEAEPQL-PPAPVRGGSSREAVQR-GLNSWQQQQQQQQQP-RPPPRQQERAHL 672
R + ++ V G + EA +R L++ ++ P P P R+
Sbjct: 123 TTRPGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRA 182
Query: 673 ESLVASRPSPQPLAETPIPSLPEFPRAASQQEIEQSIETLNMLMLDLEPASAAAPLHKSQ 732
P P P A P+ E PR + E S + A S+
Sbjct: 183 AGTEVGLPRPAPSARPRPPT--EGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASR 240
Query: 733 SVPGAWPGASPLSSQPLSGSSRQSHP---------------------LTQSRSGYIP--- 768
S+ + A+PLSS SG S + P +T R P
Sbjct: 241 SLSSS---ATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALG 297
Query: 769 --SGHSLGTPEPAPRASLESVPPGRSYSPYDYQPCLAGPNQDFHSK---SPASSSLPAFL 823
S L TP P+ + PP + +P P P+ + +P S S P L
Sbjct: 298 PLSSSPLATPSPSGTKARPVPPPDNAATPL---PATLPPSPPLATPLPLAPPSPSAPPSL 354
Query: 824 PTTHSPPG--PQQPPASL--------PGLTAQPLLSPKEATSDPSRTPEEEPLNLEGLVA 873
T SPP P Q P S+ P L P + + + PS PL L L A
Sbjct: 355 QTLPSPPATPPSQAPPSMTTPPMQAPPSLQTIPPIQVPHSLTSPSLQAPPSPLALSSLQA 414
Query: 874 HRVAG---VQAREKQPAEPPAPLRRRAASDGQYENQSPEATSPRSPGVRSPVQC-VSPEL 929
G +QA P + S + P +T P SP +++P+ SP L
Sbjct: 415 TTSLGSPTLQATHSFLTMSPRQTQASLTSPSR-----PASTPPDSPPLQAPLSLPASPPL 469
Query: 930 --ALTIALNPGGRPKEPHLHSYKEAFEEMEGTSPSSP------PPSGVRS---PPGLAKT 978
+L+ A++P P H +A + SP +P PP +S PP L +T
Sbjct: 470 QTSLSPAVSPLSSPLTIH---PLQALSSLASHSPQAPLSSLIMPPLETQSSLAPPSL-QT 525
Query: 979 PLSALGLKPHNPADILLHP------TGVTRRRIQPEEDEGKVVVR-----LSEEPRSYVE 1027
P ++L P L P +T ++ ++ L+ P
Sbjct: 526 PPASLTTPPLENLPSLAPPPLQTASAPLTTPHLETPPCPAPCPLQAPPSPLTTPPPETPS 585
Query: 1028 SVARTAVAGPRAQDSEP-KSFSAPATQAYGHEIPLRNGTLGGSFVSPSPLSTSSPILSAD 1086
S+A P A S P + +P P L + P +SP LS
Sbjct: 586 SIATPPPQAPPALASPPLQGLPSPPLSPLATPPPQAPPXLALPPLQAPPSPPASPPLSPL 645
Query: 1087 STSVGSFPSGESSD--QGP-RTPTQPLLESGFRSGSLGQPSPSAQRNYQ-----SSSPLP 1138
+T P+ + Q P P P +++ F + SPSA Q ++ PL
Sbjct: 646 ATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQ 705
Query: 1139 TVGSSYSSPDYSLQHFSSSPESQARAQFSVAGVHTVPGSPQARHRTVGTNTPPSPGFGWR 1198
S +SP S S++P QA + + VP SP A + TPP
Sbjct: 706 VPPSPPASPPMSP---SATPPPQAPPPLAAPPLQ-VPPSPPASPPMSPSATPPPRVPPLL 761
Query: 1199 AINPSMAAPSSP-SLSHHQMMGP------------------PGTGFHGSTVSSPQSSAAT 1239
A P PS P SL + P P F G +P S +A+
Sbjct: 762 AAPPLQVPPSPPASLPMSPLAKPPPQAPPALATPPLQALPSPPASFPG---QAPFSPSAS 818
Query: 1240 TPGSPSLCRHP-AGVYQVSGLHNKVATTPGSPSL---GRHPGAHQGNLASGLHSNAIASP 1295
P SP P A + L + P SP+L R P SG +P
Sbjct: 819 LPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAP 878
Query: 1296 GSPSLGRHLGGSGSVVPGSPCLDRHVAYGGYSTPEDRRPTLSRQSSASGYQAPSTPSFPV 1355
G P S S P L H + STPE+ R S G A S P
Sbjct: 879 GPPPPPSR---SPSSTLSGPDLAGH-SSSATSTPEELR---GYDSGPEGGAAASPPPDAE 931
Query: 1356 SPAYYPGLSSPATSPSPDSAAFRQGSPTPALPEKRRMSVGDRAGSLPNYATINGKVSSPV 1415
A +P S +P AFR G+P LP G G Y T + ++P
Sbjct: 932 LAACHPAAWSRGPAP---PLAFR-GAPGAPLPWPPATGPGSADGLCTIYETEGPESATPA 987
Query: 1416 ASGMS-SPSGGST 1427
+ PS G++
Sbjct: 988 PGALDPGPSPGTS 1000
Score = 52.8 bits (125), Expect = 3e-06
Identities = 113/467 (24%), Positives = 164/467 (35%), Gaps = 77/467 (16%)
Query: 965 PPSGVRSPPGLAKTPLSALGLKPHNPADILLHPTG----VTRRRIQPEEDEGKVVVRLSE 1020
PP R PP + L LG L G T P + S
Sbjct: 29 PPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRAGPTRSAGTSSR 88
Query: 1021 EPRSYVESVARTAVAGPRAQDSEPKSFSAPATQAYGHEIPLRNGTLGGSFVSPSPLSTSS 1080
P S + R A P A+++ P S+P +A G P G LG + S T +
Sbjct: 89 NPASRPPASGRGERAPP-AKNTSPGPVSSPG-RASGTTRP---GPLGQKGLRISAEETVA 143
Query: 1081 PILSADSTSVGSFPSGESSDQGPRTPTQPLLESGFRSGSLG------QPSPSAQRNYQSS 1134
+ ++ + +G D TP P RS + G +P+PSA+ +
Sbjct: 144 RGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTE 203
Query: 1135 SPLPTVGSSYSSPDYSLQHFSSSPESQARAQFSVAG-----------VHTVPGSPQARHR 1183
P +V S+ +H ++ P AR + S G P S AR
Sbjct: 204 GPRKSVSSAS-------EHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSG 256
Query: 1184 TVGTNTPPSPGF-------GWRAINPSM-------AAPSSPSLSHHQMMGPPGTGFHGST 1229
TP +P G +A+ P AAP+ LS + P +G
Sbjct: 257 PSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSGTKARP 316
Query: 1230 VSSPQSSA----ATTPGSPSLCR-------HPAGVYQVSGLHNKVATTPGS--PSLGRHP 1276
V P ++A AT P SP L P+ + L + AT P PS+ P
Sbjct: 317 VPPPDNAATPLPATLPPSPPLATPLPLAPPSPSAPPSLQTLPSPPATPPSQAPPSMTTPP 376
Query: 1277 GAHQGNLAS--------GLHSNAIASPGSPSLGRHLGGSGSVVPGSPCLDRHVAYGGYST 1328
+L + L S ++ +P SP L + S+ GSP L ++ S
Sbjct: 377 MQAPPSLQTIPPIQVPHSLTSPSLQAPPSPLALSSLQATTSL--GSPTLQATHSFLTMS- 433
Query: 1329 PEDRRPTLSRQSSASGYQAPSTP-----SFPVSPAYYPGLSSPATSP 1370
P + +L+ S + S P S P SP L SPA SP
Sbjct: 434 PRQTQASLTSPSRPASTPPDSPPLQAPLSLPASPPLQTSL-SPAVSP 479
>gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapiens]
Length = 816
Score = 85.5 bits (210), Expect = 4e-16
Identities = 194/815 (23%), Positives = 267/815 (32%), Gaps = 174/815 (21%)
Query: 556 GGGYPYESASRAGPAHAGHTAPMRPSYSAQEGLAGYQREGPHPAWPQPVTTSHYAHDPSG 615
GG ESA RAGP T RP S + G + P PV++ A SG
Sbjct: 66 GGATIPESAPRAGP-----TRTSRPPASGR----GERAPPAKNTSPGPVSSPGRA---SG 113
Query: 616 MFRSQSFSEAEPQLPPAP-VRGGSSREAVQRG-LNSWQQQQQQQQQP-RPPPRQQERAHL 672
R + ++ V G + EA +R L++ ++ P P P R+
Sbjct: 114 TTRPGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRA 173
Query: 673 ESLVASRPSPQPLAETPIPSLPEFPRAASQQEIEQSIETLNMLMLDLEPASAAAPLHKSQ 732
P P P A P+ E PR + E S + A S+
Sbjct: 174 AGTEVGLPRPAPSARPRPPT--EGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASR 231
Query: 733 SVPGAWPGASPLSSQPLSGSSRQSHP---------------------LTQSRSGYIP--- 768
S+ + A+PLSS SG S + P +T R P
Sbjct: 232 SLSSS---ATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALG 288
Query: 769 --SGHSLGTPEPAPRASLESVPPGRSYSPYDYQPCLAGPNQDFHSK-SPASSSLPAFLPT 825
S L TP P+ S S PP P P P+Q S SP + +FLP+
Sbjct: 289 PLSSSPLATPSPSAPPS-PSAPPSLQTLP---SPPATPPSQATTSLGSPTLQATHSFLPS 344
Query: 826 THSPPGPQQPPASLPGLTAQPLLSPKEATSDPSRTPEEEPLNLEGLVAHRVAGVQAREKQ 885
P PP + P L PL +P + P +P P + + A V +QA
Sbjct: 345 PPLSPLATPPPQAPPALALPPLQAPPSPPASPPLSPLATP-SPQAPNALAVHLLQAPFSP 403
Query: 886 PAEPP--APLRRRAASDGQYENQSPEATSPRSPGVRSPVQCVSPELALTIALNPGGRPKE 943
P PP AP SP A+ P SP P Q P LA P P
Sbjct: 404 PPSPPVQAPF-------------SPPASPPVSPSATPPSQ-APPSLAAPPLQVPPSPPAS 449
Query: 944 PHLHSYKEAFEEMEGTSPSSPPPSGVRSPPGLAKTPLSALGLKPHNPADILLHPTGVTRR 1003
P + SPS+ PP ++PP LA PL P P + P
Sbjct: 450 PPM-------------SPSATPPP--QAPPPLAAPPLQLAKPPPQAPPALATPPL----- 489
Query: 1004 RIQPEEDEGKVVVRLSEEPRSYVESVARTAVAGPRAQDSEPKSFSAPATQAYGHEIPLRN 1063
+A S P SF A + +P+
Sbjct: 490 ----------------------------------QALPSPPASFPGQAPFSPSASLPM-- 513
Query: 1064 GTLGGSFVSPSPLST----SSPILSADSTSVGSFPSGESSDQGPRTPTQPLLESGFRSGS 1119
SPL+T + P+L+A V P + Q PR P P ++
Sbjct: 514 ----------SPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPR 563
Query: 1120 L-------GQPSPSAQRNYQSSSP-LPTVGSSYSSPDYSLQHFSSSPESQARA----QFS 1167
L P PS + S P L SS +S L+ + S PE A A
Sbjct: 564 LTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAE 623
Query: 1168 VAGVHTV-----PGSPQARHRTVGTNTPPSPGFG----------WRAINPSMAAPSSPSL 1212
+A H P P A G P P G + P A P+ +L
Sbjct: 624 LAACHPAAWSRGPAPPLAFRGAPGAPLPWPPATGPGSADGLCTIYETEGPESATPAPGAL 683
Query: 1213 SHHQMMGP-PGTGFHGSTVSSPQSSAATTPGSPSLCRHPAGVYQVSGLHNKVATT----P 1267
GP PGT + + +++ +P L P G Q S + + ++ T
Sbjct: 684 D----PGPSPGTSGGKAAAGAGAGASSRSPKQARLGELPLGALQASVVQHLLSRTLLLAA 739
Query: 1268 GSPSLGRHPGAHQGNLASGLHSNAIASPGSPSLGR 1302
+ G G G G+ A A+ LGR
Sbjct: 740 AEGAAGGSGGGPGGAEGGGVTGGARAALSDAELGR 774
Score = 60.8 bits (146), Expect = 1e-08
Identities = 134/569 (23%), Positives = 198/569 (34%), Gaps = 120/569 (21%)
Query: 906 QSPEATSPRSPGVRSPVQCVSPELALTIALNPGGRPKEPHLH--------SYKEAFEEME 957
++P +PR PG P V+P AL + G ++P + E+
Sbjct: 20 RAPGLLTPRPPGSPRPPPPVTPA-ALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRAG 78
Query: 958 GTSPSSPPPSG--VRSPPG--LAKTPLSALGLKPHNPADILLHPTGVTRRRIQPEEDEGK 1013
T S PP SG R+PP + P+S+ G P G RI EE +
Sbjct: 79 PTRTSRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRP---GPLGQKGLRISAEETVAR 135
Query: 1014 VVVRLSEEP-RSYVESVARTAVAGPRAQDSEPKSFSAPATQAYGHEIPLRNGTLGGSFVS 1072
+ +E P RS + + AR +GP P A ++A G E+ L
Sbjct: 136 G--KATEAPKRSALSAGARRDTSGPTP--GTPSPAMARRSRAAGTEVGL----------- 180
Query: 1073 PSPLSTSSPILSADSTSVGSFPSGESSDQGPRTPTQPLLESGFRSGSLGQPSPSAQRNYQ 1132
P P ++ P +GPR E S +PSP+A+R
Sbjct: 181 PRPAPSARP---------------RPPTEGPRKSVSSASEH-----STTEPSPAARRR-- 218
Query: 1133 SSSPLPTVGSSYSSPDYSLQHFSSSP-ESQARAQFSVAGVHTVPGSP-QARHRTVGTNTP 1190
P+ G P S++P S AR+ S G P P Q + + + P
Sbjct: 219 -----PSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRP 273
Query: 1191 P---------SPGFGWRAINP----SMAAPSSPSLSHHQMMGPPGTGFHGSTVSSPQSSA 1237
P +P G + +P S +AP SPS PP S ++P S A
Sbjct: 274 PQVTPPRKDAAPALGPLSSSPLATPSPSAPPSPS-------APPSLQTLPSPPATPPSQA 326
Query: 1238 ATTPGSPSLCRHPAGVYQVSGLHNKVATTPGSPSLGRHPGAHQGNLASGLHSNAIASPGS 1297
T+ GSP+L H+ + + P SP P A L + +P S
Sbjct: 327 TTSLGSPTL----------QATHSFLPSPPLSPLATPPPQA-----PPALALPPLQAPPS 371
Query: 1298 PSLGRHLGGSGSVVPGSP-CLDRHVAYGGYSTPED----------RRPTLSRQSSASGYQ 1346
P L + P +P L H+ +S P P +S ++
Sbjct: 372 PPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQA 431
Query: 1347 APST--------PSFPVSPAYYPGLSSPATSPSPDSA-----AFRQGSPTPALPEKRRMS 1393
PS PS P SP P + P +P P +A A PAL +
Sbjct: 432 PPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQA 491
Query: 1394 VGDRAGSLPNYATINGKVSSPVASGMSSP 1422
+ S P A + S P++ + P
Sbjct: 492 LPSPPASFPGQAPFSPSASLPMSPLATPP 520
>gi|18079216 CASK interacting protein 1 [Homo sapiens]
Length = 1431
Score = 80.9 bits (198), Expect = 1e-14
Identities = 187/827 (22%), Positives = 275/827 (33%), Gaps = 128/827 (15%)
Query: 632 APVRGGSSREAVQRGLNSWQQQQQQQQQPRPPPRQ-------QERAHLESLVASRPSPQ- 683
A GG R + L + +P P Q Q+ + L A+ P
Sbjct: 611 AKYEGGPLRRKAPQSLEVMAIESPPPPEPTPADCQSPKMTTFQDSELSDELQAAMTGPAE 670
Query: 684 --PLAETPIPSLPEFPRAASQQEIEQSIETLNML----MLDLEPASAAAPLHKSQSV--- 734
P E P LP PRA ++Q+ +M +L P ++P+ +SQ
Sbjct: 671 VGPTTEKPSSHLPPTPRATTRQDSSLGGRARHMSSSQELLGDGPPGPSSPMSRSQEYLLD 730
Query: 735 PGAWPGASPLSSQPLSGSSRQSHPLTQSRSGYIPSGHSLGTPEPAPRASLESVPPGRSY- 793
G PG P ++P R H + ++ + P P + +PPG S+
Sbjct: 731 EGPAPGTPPREARP----GRHGHSIKRA------------SVPPVPGKPRQVLPPGTSHF 774
Query: 794 ----SPYDYQP----CLAGPNQDFHSKSPASSSL---PAFLPTTHSPPGPQQPPAS---- 838
+P +P L GP H +PA++ + P LP T P P+ P S
Sbjct: 775 TPPQTPTKTRPGSPQALGGP----HGPAPATAKVKPTPQLLPPTERPMSPRSLPQSPTHR 830
Query: 839 -LPGLTAQPLLSPKEATSDPSRTPEEEPLNLEGLVAHRVAGVQAREKQPAEPPAPLRRRA 897
+ QP + + + P P P + L A A +P + L R A
Sbjct: 831 GFAYVLPQP-VEGEVGPAAPGPAPPPVPTAVPTLCLPPEA--DAEPGRPKKRAHSLNRYA 887
Query: 898 ASDGQYENQSPEATSPRSPGVRSPVQCVSPELALTIALN-PGGRPKEPHLHSYKEAFEEM 956
ASD + PE P P V + + ++ P G K +
Sbjct: 888 ASDSE-----PERDELLVPAAAGPYATVQRRVGRSHSVRAPAGADKNVNRSQSFAVRPRK 942
Query: 957 EGTSPSSPPPSGVRSPPGLAKTPLSALGLKPHNPADILLHPTGVTRRRIQPEEDEGKVVV 1016
+G PPP RS LA L+ + P D LL GV + + + G V
Sbjct: 943 KG----PPPPPPKRSSSALASANLADEPVPDAEPEDGLL---GVRAQCRRASDLAGSVDT 995
Query: 1017 RLSEEPRSYVESVARTAV-AGPRAQDSEPKSFSAPATQAYGHEIPLRNGTLGGSFVSPSP 1075
+ +S + +++ G RA P+ P + P R T+ S
Sbjct: 996 GSAGSVKSIAAMLELSSIGGGGRAARRPPEGHPTPRPAS---PEPGRVATVLASVKHKEA 1052
Query: 1076 LSTSSPILSADSTSVGSFPS---------GESSDQGPRTPTQPLLESGFRSGSLGQPSPS 1126
+ +++ T G GES+D G P +E G +G PS
Sbjct: 1053 IGPGGEVVNRRRTLSGPVTGLLATARRGPGESADPG------PFVEDG--TGRQRPRGPS 1104
Query: 1127 AQRNYQSSSPLPTVGSSYSSPDYSLQHFSSSPESQARAQFSVAGVHTVPGSPQARHRTVG 1186
PL V +S + + + Q +F + TV P+A+ R G
Sbjct: 1105 KGEAGVEGPPLAKVEASATLK----RRIRAKQNQQENVKFILTESDTVKRRPKAKEREAG 1160
Query: 1187 TNTPPSPGFGWRAINPSMAAPSSPSLSHHQMMGPPGTGFHGSTVSSPQSSAATTPGSPSL 1246
PP P+S + GPP P + A P P
Sbjct: 1161 PEPPPPLSVYHNGTGTVRRRPAS------EQAGPPELPPPPPPAEPPPTDLAHLPPLP-- 1212
Query: 1247 CRHPAGVYQVSGLHNKVATTPGSPS--LGRHPGAHQGNLASGLHSNAIASPGSPSLGRHL 1304
G K A P SP L + QG+ + PGSP + R
Sbjct: 1213 --------PPEGEARKPAKPPVSPKPVLTQPVPKLQGSPTPTSKKVPLPGPGSPEVKRAH 1264
Query: 1305 GGSGSVVPGSP-------CLDRHVAYGGYSTPEDRRPTLSRQSSASGYQAPST-PSFPVS 1356
G V P P + S P+ +RQ A+ + P T PS S
Sbjct: 1265 GTPPPVSPKPPPPPTAPKPVKAVAGLPSGSAGPSPAPSPARQPPAALAKPPGTPPSLGAS 1324
Query: 1357 PAY-----YPGLSSPATSPSPDSAAFRQGSPTPALPEKRRMSVGDRA 1398
PA P L PA P +AA + PA PE S GD A
Sbjct: 1325 PAKPPSPGAPALHVPAKPPRAAAAAAAAAAAPPAPPE--GASPGDSA 1369
Score = 38.9 bits (89), Expect = 0.044
Identities = 81/353 (22%), Positives = 115/353 (32%), Gaps = 74/353 (20%)
Query: 587 GLAGYQREGP-HPAWPQPVTTSHYAHDPSGMFRSQSFSEAEPQLPPAPVRGGSSREAVQR 645
GL R GP A P P + D +G R + S+ E + P+ + ++R
Sbjct: 1072 GLLATARRGPGESADPGP-----FVEDGTGRQRPRGPSKGEAGVEGPPLAKVEASATLKR 1126
Query: 646 GLNSWQQQQQ--------------------QQQQPRPPPRQQERAHLESLVASRPSPQPL 685
+ + Q QQ+ ++ P PPP + V RP+ +
Sbjct: 1127 RIRAKQNQQENVKFILTESDTVKRRPKAKEREAGPEPPPPLSVYHNGTGTVRRRPASEQA 1186
Query: 686 AETPIPSLPEFPRAASQQEIEQSIETLNMLMLDLEPASAAAPLHKSQSVPGAWPGASPLS 745
P LP P A + + L P + + P P P+
Sbjct: 1187 GP---PELPPPPPPAEPPPTD---------LAHLPPLPPPEGEARKPAKPPVSP--KPVL 1232
Query: 746 SQP---LSGS---SRQSHPLTQSRSGYIPSGHSLGTPEPAPRASLESVPPGRSYSPYDYQ 799
+QP L GS + + PL S + H GTP P S + PP + P
Sbjct: 1233 TQPVPKLQGSPTPTSKKVPLPGPGSPEVKRAH--GTPPPV---SPKPPPPPTAPKPVK-- 1285
Query: 800 PCLAGPNQDFHSKSPASSSLPAFLPTTHSPPGPQQPPASLPGLTAQPLLSPKEATSDPSR 859
+AG SPA S P P +PP + P L A P P
Sbjct: 1286 -AVAGLPSGSAGPSPAPS------PARQPPAALAKPPGTPPSLGASPAKPP--------- 1329
Query: 860 TPEEEPLNLEGLVAHRVAGVQAREKQPAEPPAPLRRRAASDGQYENQSPEATS 912
+P L++ A A P PP AS G Q E TS
Sbjct: 1330 SPGAPALHVPAKPPRAAAAAAAAAAAPPAPP-----EGASPGDSARQKLEETS 1377
>gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo
sapiens]
Length = 5537
Score = 75.9 bits (185), Expect = 3e-13
Identities = 199/877 (22%), Positives = 279/877 (31%), Gaps = 149/877 (16%)
Query: 662 PPPRQQERAHLESLVASRPSPQPLAETPIPS-------LPEFPRAASQQEIEQSIETLNM 714
PPP + + P P+ L +P+P L E P + +E S +
Sbjct: 451 PPPEESPTSPPPEASRLSPPPEELPASPLPEALHLSRPLEESPLSPPPEESPLSPPPESS 510
Query: 715 LMLDLEPASAAAPLHKSQSVPGAWPGASPLSSQPLS---GSSRQSHPLTQSRSGYIPSGH 771
LE + + P S P + P + PLS S S P + + P
Sbjct: 511 PFSPLEESPLSPPEESPPSPALETPLSPPPEASPLSPPFEESPLSPPPEELPTSPPPEAS 570
Query: 772 SLGTP------EPAPRASLESVPP--GRSYSPYDYQPCLAGPNQDFHSKSPASSSLPAFL 823
L P P P S S PP R + P++ P P + S P +S L
Sbjct: 571 RLSPPPEESPMSPPPEESPMSPPPEASRLFPPFEESPLSPPPEESPLSPPPEASRLSP-- 628
Query: 824 PTTHSP--PGPQQPPASLPGLTAQPLLSPKEATSDPSRTPEEEPLNLEGLVAHRVAGVQA 881
P SP P P++ P S P ++ LSP S S PEE PL+
Sbjct: 629 PPEDSPMSPPPEESPMSPPPEVSR--LSPLPVVSRLSPPPEESPLS------------PP 674
Query: 882 REKQPAEPPAPLRRRAASDGQYENQSPEATSPRSPGVRSPVQCVSPELALTIAL------ 935
E+ P PP R + P SP SP + + E + + L
Sbjct: 675 PEESPTSPPPEASRLSPPPEDSPTSPPPEDSPASPPPEDSLMSLPLEESPLLPLPEEPQL 734
Query: 936 -------NPGGRPKEPHL-------HSYKEAFEEMEGTSPSSP-----PPSGVRSP---- 972
+ RP+EPHL H +A E P P P SP
Sbjct: 735 CPRSEGPHLSPRPEEPHLSPRPEEPHLSPQAEEPHLSPQPEEPCLCAVPEEPHLSPQAEG 794
Query: 973 PGLAKTP----LSALGLKPH---NPADILLHPTGVTRRRIQPEEDEGKVVVRLSEEP--- 1022
P L+ P LS +PH P + L P QPEE + SEEP
Sbjct: 795 PHLSPQPEELHLSPQTEEPHLSPVPEEPCLSP--------QPEESH---LSPQSEEPCLS 843
Query: 1023 ----RSYVESVARTAVAGPRAQDSEPKSFSAPATQAYGHEIPLRNGTLGGSFVSPSPLST 1078
S++ PR + + PA + P +L P+
Sbjct: 844 PRPEESHLSPELEKPPLSPRPEKPPEEPGQCPAPEELPLFPPPGEPSLSPLLGEPALSEP 903
Query: 1079 SSPILSADSTSVGSFPSGESSDQGPRTPTQPLLESGFRSGSLGQPSPSAQRNYQSSSPLP 1138
P LS + PSGE S P PL P P SP+
Sbjct: 904 GEPPLSPLPEELPLSPSGEPSLSPQLMPPDPL------------PPP--------LSPII 943
Query: 1139 TVGSSYS-SPDYSLQH-FSSSPESQARAQFSVAGVHTVPGSPQARHRTVGTN------TP 1190
T + + SP L++ F + +S + + A + P SP P
Sbjct: 944 TAAAPPALSPLGELEYPFGAKGDSDPESPLA-APILETPISPPPEANCTDPEPVPPMILP 1002
Query: 1191 PSPGFGWRAINPSMAAPSSPSLS---HHQMM---GPPGTGFHGSTVSSPQSSAATTPGSP 1244
PSPG +P + P P S H ++ PP + SP + + P
Sbjct: 1003 PSPGSPVGPASPILMEPLPPQCSPLLQHSLVPQNSPP-------SQCSPPALPLSVPSPL 1055
Query: 1245 SLCRHPAGVYQVSGLHNKVATTPGSPSLGRHPGAHQGNLASGLHSNAIASPG-SPSLGRH 1303
S GV + LH P + L S + + +P +P+L
Sbjct: 1056 SPIGKVVGVSDEAELHEMETEKVSEPECPALEPSATSPLPSPMGDLSCPAPSPAPALDDF 1115
Query: 1304 LGGSGSVVPGSPCLDRHVAYGGYSTPEDRRPTLSRQSSASGYQAPSTPSFPVSP-AYYPG 1362
G P LD A G P +L+ + S PV+P YP
Sbjct: 1116 SGLGEDTAP----LDGIDAPGSQPEPGQTPGSLASELKGSPVLLDPEELAPVTPMEVYPE 1171
Query: 1363 LSSPATSPSPDSAAFRQGSPTPALP----------EKRRMSVGDRAGSLPNYATINGKVS 1412
A SP +P P E +S GD + S P + G
Sbjct: 1172 CKQTAGQGSPCEEQEEPRAPVAPTPPTLIKSDIVNEISNLSQGDASASFPGSEPLLGS-P 1230
Query: 1413 SPVASGMSSPSGGSTVSFSHTLPDFSKYSMPDNSPET 1449
P G S G + S + S D+ PET
Sbjct: 1231 DPEGGGSLSMELGVSTDVSPARDEGSLRLCTDSLPET 1267
Score = 66.6 bits (161), Expect = 2e-10
Identities = 218/913 (23%), Positives = 309/913 (33%), Gaps = 162/913 (17%)
Query: 534 PEAL--SPLTNGLDKSYPMEPMVNGGGYPYESASRAGPAHAGHTAPMRPSYSAQEGLAGY 591
PE L SPL L S P+E P E + + P + +P+ S L+
Sbjct: 471 PEELPASPLPEALHLSRPLEESPLSP--PPEESPLSPPPESSPFSPLEES-----PLSPP 523
Query: 592 QREGPHPAWPQPVTTSHYAHDPSGMFRSQSFSEAEPQLPPAPVRGGSSREAVQRGLNSWQ 651
+ P PA P++ A S F S +LP +P S S
Sbjct: 524 EESPPSPALETPLSPPPEASPLSPPFEESPLSPPPEELPTSPPPEASRLSPPPE--ESPM 581
Query: 652 QQQQQQQQPRPPPRQQERAHLESLVASRPSPQPLAETPIPSLPEFPRAASQQEIEQSIET 711
++ PPP E + L P P E+P+ PE R + E
Sbjct: 582 SPPPEESPMSPPP---EASRLFPPFEESPLSPPPEESPLSPPPEASRLSPPPE------- 631
Query: 712 LNMLMLDLEPASAAAPLHKSQSVPGAWPGASPLSSQPLSGSSRQSHPLTQSRSGYIPSGH 771
+ + P S P P S LS PL SR S P +S P
Sbjct: 632 --------DSPMSPPPEESPMSPP---PEVSRLS--PLPVVSRLSPPPEESPLSPPPEE- 677
Query: 772 SLGTPEPAPRASLESVPPGRSYSPYDYQPCLAGPNQDFHSKSPASSSLPAFLPTTHSP-- 829
P P AS S PP S + + P +D + P SL + LP SP
Sbjct: 678 --SPTSPPPEASRLSPPPEDSPT--------SPPPEDSPASPPPEDSLMS-LPLEESPLL 726
Query: 830 PGPQQPPASLPGLTAQPLLSPKEATSDPSRTPEEEPLNLEGLVAHRVAGVQAREKQPAEP 889
P P++P L + P LSP+ S PEE L+ + H QP EP
Sbjct: 727 PLPEEP--QLCPRSEGPHLSPRPEEPHLSPRPEEPHLSPQAEEPH-------LSPQPEEP 777
Query: 890 -----PAPLRRRAASDGQYENQSPEATSPRSPGVRSPVQCVSPELALTIALNPGGRPKEP 944
P ++G + + PE SP P PE L+P +P+E
Sbjct: 778 CLCAVPEEPHLSPQAEGPHLSPQPEELH-LSPQTEEPHLSPVPE---EPCLSP--QPEES 831
Query: 945 HLHSYKEAFEEMEGTSPSSPPPSGVRSPPGLAKTPLSALGLKPHNPADILLHPTGVTRRR 1004
HL E SP P P L K PLS +P P +
Sbjct: 832 HLSPQSE-------EPCLSPRPEESHLSPELEKPPLSP---RPEKPPEEPGQCPAPEELP 881
Query: 1005 IQPEEDEGKVVVRLSEEPRSYVESVARTAVAGPRAQDSEPKSFSAPATQAYGHEIPLRNG 1064
+ P E + L E A++ P P P + P
Sbjct: 882 LFPPPGEPSLSPLLGE-----------PALSEPGEPPLSPLPEELPLS-------PSGEP 923
Query: 1065 TLGGSFVSPSPLSTS-SPILSADSTSVGS------FPSGESSDQGPRTP-TQPLLESGFR 1116
+L + P PL SPI++A + S +P G D P +P P+LE+
Sbjct: 924 SLSPQLMPPDPLPPPLSPIITAAAPPALSPLGELEYPFGAKGDSDPESPLAAPILETPI- 982
Query: 1117 SGSLGQPSPSAQRNYQSSSPLPTVGSSYSSPDYSLQHFSSSPESQARAQFSVAGVHTVPG 1176
SP + N P+P + L SP A S + +P
Sbjct: 983 -------SPPPEANCTDPEPVPPM---------ILPPSPGSPVGPA----SPILMEPLPP 1022
Query: 1177 --SPQARHRTVGTNTPPSPGFGWRAINPSMAAPSSP---------SLSHHQM----MGPP 1221
SP +H V N+PPS A+ S+ +P SP H+M + P
Sbjct: 1023 QCSPLLQHSLVPQNSPPSQ-CSPPALPLSVPSPLSPIGKVVGVSDEAELHEMETEKVSEP 1081
Query: 1222 GTGFHGSTVSSPQSSAATTPGSPSLCRHPAGVYQVSGLHNKVATTPG--SPSLGRHPGAH 1279
+ +SP S P+ PA + SGL A G +P PG
Sbjct: 1082 ECPALEPSATSPLPSPMGDLSCPAPSPAPA-LDDFSGLGEDTAPLDGIDAPGSQPEPGQT 1140
Query: 1280 QGNLASGLHSNAI------ASPGSPSLGRHLGGSGSVVPGSPCLDRHVAYGGYS-TPEDR 1332
G+LAS L + + +P +P + + + GSPC ++ + TP
Sbjct: 1141 PGSLASELKGSPVLLDPEELAPVTP-MEVYPECKQTAGQGSPCEEQEEPRAPVAPTP--- 1196
Query: 1333 RPTLSRQSSASGYQAPSTPSFPVSPAYYPGLSSPATSPSPD---SAAFRQGSPTPALPEK 1389
PTL + + S S + A +PG SP P+ S + G T P +
Sbjct: 1197 -PTLIKSDIVNEI---SNLSQGDASASFPGSEPLLGSPDPEGGGSLSMELGVSTDVSPAR 1252
Query: 1390 RRMSVGDRAGSLP 1402
S+ SLP
Sbjct: 1253 DEGSLRLCTDSLP 1265
Score = 64.3 bits (155), Expect = 1e-09
Identities = 158/654 (24%), Positives = 209/654 (31%), Gaps = 102/654 (15%)
Query: 746 SQPLSGSSRQSHP--LTQSRSGYIPSGH--SLGTPEPAPRASLESVPPGRSYSPYDYQPC 801
S P G + P L + G GH S+ EP P E+ P G+
Sbjct: 373 SPPEPGDTPTDEPDALYVACQGQPKGGHVTSMQPKEPGP-LQCEAKPLGK---------- 421
Query: 802 LAGPNQDFHSKSPASSSLPAFLPTTHSP--PGPQQPPASLPGLTAQPLLSPKEATSDP-- 857
AG + ++P + +P P SP P P++ P S P ++ P+E + P
Sbjct: 422 -AGVQLEPQLEAPLNEEMPLLPPPEESPLSPPPEESPTSPPPEASRLSPPPEELPASPLP 480
Query: 858 -----SRTPEEEPLNLEGLVAHRVAGVQAREKQPAEPP------APLRRRAASDGQYENQ 906
SR EE PL+ E+ P PP +PL S +
Sbjct: 481 EALHLSRPLEESPLS------------PPPEESPLSPPPESSPFSPLEESPLSPPEESPP 528
Query: 907 SPEATSPRSPGVR-SPVQCVSPELALTIALN--PGGRPKEPHLHSYKEAFEEME---GTS 960
SP +P SP SP+ E L+ P P E S M S
Sbjct: 529 SPALETPLSPPPEASPLSPPFEESPLSPPPEELPTSPPPEASRLSPPPEESPMSPPPEES 588
Query: 961 PSSPPPSGVRSPPGLAKTPLSALGLKPHNPADILLHPTGVTRRRIQPEEDEGKVVVRLSE 1020
P SPPP R P ++PLS P + L P R P ED + E
Sbjct: 589 PMSPPPEASRLFPPFEESPLSP------PPEESPLSPPPEASRLSPPPED-SPMSPPPEE 641
Query: 1021 EPRSYVESVARTA---VAGPRAQDSEPKSFSAPATQAYGHEIPLRNGTLGGSFVSP-SPL 1076
P S V+R + V + E S P ++ P + SP SP
Sbjct: 642 SPMSPPPEVSRLSPLPVVSRLSPPPEESPLSPPPEESPTSPPPEASRLSPPPEDSPTSPP 701
Query: 1077 STSSPILSADSTSVGSFPSGESSDQGPRTPTQPLLESGFRSGSLGQPSPSAQRNYQSSSP 1136
SP S+ S P ES P PL E P S + SP
Sbjct: 702 PEDSPASPPPEDSLMSLPLEES-------PLLPLPEEPQLCPRSEGPHLSPRPEEPHLSP 754
Query: 1137 LPTVGSSYSSPDYSLQHFSSSPESQARAQFSVAGVHTVPGSPQARHRTVGTNTPPSPGFG 1196
P + SP H S PE + VP P + G + P P
Sbjct: 755 RPE--EPHLSPQAEEPHLSPQPEEPC--------LCAVPEEPHLSPQAEGPHLSPQP--E 802
Query: 1197 WRAINPSMAAPSSPSLSHHQMMGPPGTGFHGSTVSSPQSSAATTPGSPSLCRHPAGVYQV 1256
++P P + + P H SPQS P L P +
Sbjct: 803 ELHLSPQTEEPHLSPVPEEPCLSPQPEESH----LSPQSE------EPCLSPRP----EE 848
Query: 1257 SGLHNKVATTPGSPSLGRHPGAHQGNLASGLHSNAIASPGSPSLGRHLGGSGSVVPGSPC 1316
S L ++ P SP P G + PG PSL LG PG P
Sbjct: 849 SHLSPELEKPPLSPR-PEKPPEEPGQCPAPEELPLFPPPGEPSLSPLLGEPALSEPGEPP 907
Query: 1317 LDRHVAYGGYSTPEDRRPTLSRQSSASGYQAPSTPSFPVSPAYYPGLSSPATSP 1370
L PE+ + S + S S P P P + PA SP
Sbjct: 908 LS--------PLPEELPLSPSGEPSLSPQLMPPDPLPPPLSPIITAAAPPALSP 953
Score = 53.9 bits (128), Expect = 1e-06
Identities = 185/812 (22%), Positives = 270/812 (33%), Gaps = 163/812 (20%)
Query: 526 TNTSEGGYPEALSPLTNGLDKSYPMEPMVNGGGYPYESASRAGPAHAGHTAPMRPSYSAQ 585
T+ GG+P AL G + V G P S A G +PMR ++
Sbjct: 2487 TSLGAGGFPAALPAGPAG-----ELHAKVPSGQPPNFVRSPGTGAFVGTPSPMRFTFPQA 2541
Query: 586 EGLAGYQREGPHPAWPQPV-TTSHYAHDPS-GMFRSQSFSEAEPQLPPA--PVRGGSSRE 641
G + P P P P SH+ P+ G +S +++ A P+ P+ S
Sbjct: 2542 VGEPSLKPPVPQPGLPPPHGINSHFGPGPTLGKPQSTNYTVATGNFHPSGSPLGPSSGST 2601
Query: 642 AVQRGLNSWQQQQQQQQQPRPPPRQQ-----------ERAHLESLVASRPSP-----QPL 685
GL+ + PPP +R+ + S V R P L
Sbjct: 2602 GESYGLSPLRPPSVL-----PPPAPDGSLPYLSHGASQRSGITSPVEKREDPGTGMGSSL 2656
Query: 686 AETPIPSLPEFPRAA-SQQEIE-----QSIETL--------NMLMLDLEPASAAAPLHKS 731
A +P + + SQ E+E Q + L N L + E A+AAA +
Sbjct: 2657 ATAELPGTQDPGMSGLSQTELEKQRQRQRLRELLIRQQIQRNTLRQEKETAAAAAG---A 2713
Query: 732 QSVPGAWPGASPLSSQPLSGSSRQSHPL--TQSRSGYIP------SGHSLGTPEPAPRAS 783
PG+W GA P SS SR P TQ +S + SG LG
Sbjct: 2714 VGPPGSW-GAEP-SSPAFEQLSRGQTPFAGTQDKSSLVGLPPSKLSGPILGPGSFPSDDR 2771
Query: 784 LESVPPGRSYSPYDYQPC-LAGPNQDFHSKSPASSSLPAFLPTTHSPPGPQQPPASLPGL 842
L PP + S D L G +Q F+ ++P SLP QQ
Sbjct: 2772 LSRPPPPATPSSMDVNSRQLVGGSQAFYQRAPYPGSLPL--------QQQQQQLWQQQQA 2823
Query: 843 TAQPLLSPKEATSDPSRTPEEEPLNLEGLVAHRVAGVQAREKQPAEPPAPLRRRAASDGQ 902
TA + + PS TP E L + L +AG+ R P EP
Sbjct: 2824 TAATSMRFAMSARFPS-TPGPE-LGRQAL-GSPLAGISTRLPGPGEP------------- 2867
Query: 903 YENQSPEATSPRSPGVRSPVQCVSPELALTIALNPGGR-------PKEPHLHSYKE---- 951
PG P Q + + L PGG P+ P + E
Sbjct: 2868 ------------VPGPAGPAQFIELRHNVQKGLGPGGTPFPGQGPPQRPRFYPVSEDPHR 2915
Query: 952 -AFEEMEGTSPSSPPPSGVRSPPGLAKTPLSALGLKPHNPADILLHPTGVTRRRIQPEED 1010
A E + G + S PP +PP A ++L PH L PTG+ P
Sbjct: 2916 LAPEGLRGLAVSGLPPQKPSAPP--APELNNSLHPTPHTKGPTL--PTGLELVNRPPSST 2971
Query: 1011 EGKVVVRLSEEPRSYVESVARTAVAGPRAQDSEPKSFSAPATQAYGH-----EIPLRNGT 1065
E P + P D + + H ++ +
Sbjct: 2972 E-------LGRPNPLALEAGKLPCEDPELDDDFDAHKALEDDEELAHLGLGVDVAKGDDE 3024
Query: 1066 LGGSFVSPSPLSTSSP----ILSADSTSVGSF-----PSGESSD----------QGPRTP 1106
LG + L T+ P +L+ D + ++ +G+ D
Sbjct: 3025 LG----TLENLETNDPHLDDLLNGDEFDLLAYTDPELDTGDKKDIFNEHLRLVESANEKA 3080
Query: 1107 TQPLLESGFRSGSLG---QPSPSAQRNY-QSSSPLPTV------GSSYSSPDYSLQHFSS 1156
+ L G G LG +P P+A + + +S LP V G + SP Q +
Sbjct: 3081 EREALLRGVEPGPLGPEERPPPAADASEPRLASVLPEVKPKVEEGGRHPSP---CQFTIA 3137
Query: 1157 SPESQARAQFSVAGVHTVPGSPQARHRTVGTNTPPSPGFGWRAINPSMAAPSSPSLSHHQ 1216
+P+ + + G+ PG R T P G A S A P H
Sbjct: 3138 TPKVEPAPAANSLGLGLKPGQSMMGSRDTRMGTGPFSSSGHTAEKASFGATGGPPA--HL 3195
Query: 1217 MMGPPGTGFHGSTVSSP---QSSAATTPGSPS 1245
+ P +G GS++ +S A T PG P+
Sbjct: 3196 LTPSPLSGPGGSSLLEKFELESGALTLPGGPA 3227
Score = 45.8 bits (107), Expect = 4e-04
Identities = 163/673 (24%), Positives = 233/673 (34%), Gaps = 175/673 (26%)
Query: 735 PGAWPGASPLSSQP--LSGSSRQSHPLTQSRSGYI-PSGHSLGTPEPAPRASLESVPPGR 791
PGA G+ P ++ P GS L+ S G++ P S+ P+ PG
Sbjct: 2110 PGAL-GSPPPAAAPTIFIGSPTTPAGLSTSADGFLKPPAGSVPGPDS----------PGE 2158
Query: 792 SYSPYDYQPCLAGPNQDFHSKSPASSSLPAF--LPTTHSP-PGPQQPPASLP--GLTAQP 846
+ Q P+QD +PA P F P T+ P P P PA P G +++P
Sbjct: 2159 LFLKLPPQVPAQVPSQDPFGLAPAYPLEPRFPTAPPTYPPYPSPTGAPAQPPMLGASSRP 2218
Query: 847 LLS-PKEATSDPSRTPEEEPLNLEGLVAHRVAGVQAREKQPAEPPAPLRRRAASDGQYEN 905
P E + P TP QP+ P L+ R S
Sbjct: 2219 GAGQPGEFHTTPPGTPRH---------------------QPSTPDPFLKPRCPS------ 2251
Query: 906 QSPEATSPRSPGVRSPVQCVSPELALTIALNPGGRPKEPHL---------HSYKEAFEEM 956
P SPGV GG+ EP L + + EE+
Sbjct: 2252 -LDNLAVPESPGV------------------GGGKASEPLLSPPPFGESRKALEVKKEEL 2292
Query: 957 EGTSPSSPPPS--GVRSP-------------PGLAKTPLS--ALGLKPHNPADILLHPTG 999
+SPS PP+ V SP P + K PL+ A ++P +P L
Sbjct: 2293 GASSPSYGPPNLGFVDSPSSGTHLGGLELKTPDVFKAPLTPRASQVEPQSPGLGLRPQEP 2352
Query: 1000 VTRRRIQPEEDEGKVVVRLSEEPRSYVESVARTAVAGPRAQDSEPKSFSAPATQAYGHEI 1059
+ + P + R P SY + A+ + PR Q P+S A +
Sbjct: 2353 PPAQALAPSPPSHPDIFR----PGSYTDPYAQPPLT-PRPQPPPPESCCA---------L 2398
Query: 1060 PLRNGTLGGSFVSPSPLSTSSPILSADSTSVGSFPSGESSDQGPRTPTQPLLESGFRSGS 1119
P R+ + S + V + P +SS Q P TP +PL F
Sbjct: 2399 PPRS------------------LPSDPFSRVPASPQSQSSSQSPLTP-RPLSAEAF---- 2435
Query: 1120 LGQPSPSAQRNYQSSSPLPTVGSSYSSPD-YSLQHFSSSPESQARAQFSVAGVHT---VP 1175
PSP R +QS P S S D ++ H P+ A + + HT
Sbjct: 2436 --CPSPVTPR-FQSPDPYSRPPSRPQSRDPFAPLHKPPRPQPPEVAFKAGSLAHTSLGAG 2492
Query: 1176 GSPQARHRTVGTNTPPSPGFGWRAINPSMAAPSSPSLSHHQMMGPPGTGFHGSTVSSPQS 1235
G P A P P A PS P+ + PGTG T S +
Sbjct: 2493 GFPAA--------LPAGPAGELHAKVPSGQPPN--------FVRSPGTGAFVGTPSPMRF 2536
Query: 1236 SAATTPGSPSLCRHPA---GVYQVSGLHNKVATTPGSPSLGRHPGAHQGNLASGLH-SNA 1291
+ G PSL + P G+ G+++ PG P+LG+ + H S +
Sbjct: 2537 TFPQAVGEPSL-KPPVPQPGLPPPHGINSHFG--PG-PTLGKPQSTNYTVATGNFHPSGS 2592
Query: 1292 IASPGSPSLGRHLGGS----GSVVPGSPCLDRHVAY--------GGYSTPEDRR--PTLS 1337
P S S G G S SV+P P D + Y G ++P ++R P
Sbjct: 2593 PLGPSSGSTGESYGLSPLRPPSVLP-PPAPDGSLPYLSHGASQRSGITSPVEKREDPGTG 2651
Query: 1338 RQSSASGYQAPST 1350
SS + + P T
Sbjct: 2652 MGSSLATAELPGT 2664
Score = 45.4 bits (106), Expect = 5e-04
Identities = 147/621 (23%), Positives = 198/621 (31%), Gaps = 103/621 (16%)
Query: 856 DPSRTPEEEPLNLEGLVAHRVAGVQAREKQPAEPPAPLRRRAASDGQYENQSPEATSPRS 915
+P TP +EP L + G QP EP PL+ A G+ A
Sbjct: 376 EPGDTPTDEPDALYVACQGQPKGGHVTSMQPKEP-GPLQCEAKPLGK-------AGVQLE 427
Query: 916 PGVRSPVQCVSPELALTIALNPGGRPKEPHLHSYKEAFEEMEGTSPSSPPPSGVRSPPGL 975
P + +P+ P L P+E L E SP+SPPP R P
Sbjct: 428 PQLEAPLNEEMPLLP---------PPEESPLSPPPEE-------SPTSPPPEASRLSPPP 471
Query: 976 AKTPLSALGLKPHNPADILLHPTGVTRRRIQPEED------EGKVVVRLSEEPRS-YVES 1028
+ P S L H L P + PEE E L E P S ES
Sbjct: 472 EELPASPLPEALH-----LSRPLEESPLSPPPEESPLSPPPESSPFSPLEESPLSPPEES 526
Query: 1029 VARTAVAGPRAQDSEPKSFSAPATQA----YGHEIPLRNGTLGGSFVSPSPLSTSSP--- 1081
A+ P + E S P ++ E+P P S SP
Sbjct: 527 PPSPALETPLSPPPEASPLSPPFEESPLSPPPEELPTSPPPEASRLSPPPEESPMSPPPE 586
Query: 1082 --ILSADSTSVGSFPSGESSDQGPRTPTQPLLESGFRSGSLGQPSPSAQRNYQSSSPL-P 1138
+S + FP E S P PL S P S SP+ P
Sbjct: 587 ESPMSPPPEASRLFPPFEESPLSPPPEESPLSPPPEASRLSPPPEDSPMSPPPEESPMSP 646
Query: 1139 TVGSSYSSPDYSLQHFSSSPESQARAQFSVAGVHTVPGSPQARHRTVGTNTPPSPGFGWR 1198
S SP + S PE P SP T+ PP R
Sbjct: 647 PPEVSRLSPLPVVSRLSPPPEES-------------PLSPPPEESP--TSPPPEAS---R 688
Query: 1199 AINPSMAAPSSPSLSHHQMMGPPGTGFHGSTVSSP--QSSAATTPGSPSLCRHPAGVYQV 1256
P +P+SP PP S +S P +S P P LC G + +
Sbjct: 689 LSPPPEDSPTSPPPEDSPASPPP----EDSLMSLPLEESPLLPLPEEPQLCPRSEGPH-L 743
Query: 1257 SGLHNKVATTPGSPSLGRHPGAHQGNLASGLHSNAI-ASPGSPSL-----GRHLGGSG-- 1308
S + +P P A + +L+ + A P P L G HL
Sbjct: 744 SPRPEEPHLSPRPEEPHLSPQAEEPHLSPQPEEPCLCAVPEEPHLSPQAEGPHLSPQPEE 803
Query: 1309 ------------SVVPGSPCLDRHVAYGGYSTPEDRRPTLSRQSSASGYQAPSTPSFPVS 1356
S VP PCL + +P+ P LS + S + +P P+S
Sbjct: 804 LHLSPQTEEPHLSPVPEEPCLSPQ-PEESHLSPQSEEPCLSPRPEES-HLSPELEKPPLS 861
Query: 1357 PAYYPGLSSPATSPSPDSAAFRQGSPTPALPEKRRMSVGDRAGSLPNYATINGKVSSPVA 1416
P P P+P+ P P P + +G+ A S P + SP+
Sbjct: 862 PRPEKPPEEPGQCPAPEELPL---FPPPGEPSLSPL-LGEPALSEPGEPPL-----SPLP 912
Query: 1417 SGMS-SPSGGSTVSFSHTLPD 1436
+ SPSG ++S PD
Sbjct: 913 EELPLSPSGEPSLSPQLMPPD 933
Score = 41.2 bits (95), Expect = 0.009
Identities = 91/370 (24%), Positives = 129/370 (34%), Gaps = 75/370 (20%)
Query: 534 PEALSP--LTNGLDKSYPMEPMVNGGGYPYESASRAGPAHAGHT--------APMRPSYS 583
P AL P L G +++ ++P V+ S + GP G T ++PS S
Sbjct: 4012 PGALGPTLLLTGKEQN-TVDPAVSSEATEGPSTHQGGPLAIGTTPESMATEPGEVKPSLS 4070
Query: 584 AQEGLAGYQREG-PHPA-------------WPQPVTTSHYAHDPS-GMFRSQSFSEAE-- 626
L Q + P P+ Q V+ H A S G S S SEA
Sbjct: 4071 GDSQLLLVQPQPQPQPSSLQLQPPLRLPGQQQQQVSLLHTAGGGSHGQLGSGSSSEASSV 4130
Query: 627 PQLPPAP-VRGGSSREAVQRGLNSWQQQQQQQ--------QQPRPPPRQQE--------- 668
P L P V G ++ + L QQ ++ Q P+P P Q
Sbjct: 4131 PHLLAQPSVSLGDQPGSMTQNLLGPQQPMLERPMQNNTGPQPPKPGPVLQSGQGLPGVGI 4190
Query: 669 -------RAHLESLVASRPSPQPLAETPIPSLPEFPRAASQQEIEQSIETLNMLMLDLEP 721
RA L+ ++A P + L+ P + +A Q Q + + EP
Sbjct: 4191 MPTVGQLRAQLQGVLAKNPQLRHLS----PQQQQQLQALLMQRQLQQSQAVRQTPPYQEP 4246
Query: 722 ASAAAPLHK---SQSVPGAWPGASPLSSQPLSGSSR-QSHPLTQSRSGYIPSGHSLGTPE 777
+ +PL Q G +PG Q L R Q P + G + +G LG
Sbjct: 4247 GTQTSPLQGLLGCQPQLGGFPGPQTGPLQELGAGPRPQGPPRLPAPPGALSTGPVLGPVH 4306
Query: 778 PAPRASLESVPPGRSYSPYDYQPCLAGPNQDFHSKSPASSSLPAFLPTTHSPPGP--QQP 835
P P S P S P P+ S+ P + LP P T P GP + P
Sbjct: 4307 PTPPPSSPQEPKRPSQLP--------SPS----SQLPTEAQLPPTHPGTPKPQGPTLEPP 4354
Query: 836 PASLPGLTAQ 845
P + AQ
Sbjct: 4355 PGRVSPAAAQ 4364
Score = 38.9 bits (89), Expect = 0.044
Identities = 93/393 (23%), Positives = 130/393 (33%), Gaps = 83/393 (21%)
Query: 1104 RTPTQPLLESGFRSGSLGQPSPSAQRNYQSSSPLPTVGSSYSSPDYSLQHFSSSPESQAR 1163
R P QP G+LG P P+A SP G S S+ + S P +
Sbjct: 2105 RIPPQP--------GALGSPPPAAAPTIFIGSPTTPAGLSTSADGFLKPPAGSVPGPDSP 2156
Query: 1164 AQFSVAGVHTVPGSP--------------QARHRTVGTNTPPSPG-FGWRAINPSMAAPS 1208
+ + VP + R T PP P G A P + A S
Sbjct: 2157 GELFLKLPPQVPAQVPSQDPFGLAPAYPLEPRFPTAPPTYPPYPSPTGAPAQPPMLGASS 2216
Query: 1209 SPSLSHHQMMGPPGTGFHGSTVSSPQSSAATT-----PGSPSLCRHPAGVYQVSGLHNKV 1263
P G PG FH + +P+ +T P PSL V + G+
Sbjct: 2217 RPGA------GQPGE-FHTTPPGTPRHQPSTPDPFLKPRCPSLDN--LAVPESPGVGGGK 2267
Query: 1264 ATTP--GSPSLGRHPGAHQGNLAS-GLHSNAIASPG-----SPSLGRHLGGSGSVVPGSP 1315
A+ P P G A + G S + P SPS G HLGG
Sbjct: 2268 ASEPLLSPPPFGESRKALEVKKEELGASSPSYGPPNLGFVDSPSSGTHLGGL-------- 2319
Query: 1316 CLDRHVAYGGYSTPEDRRPTLSRQSSASGYQAPSTPSFPVSPAYYPGLSSPATSPSPDSA 1375
TP+ + L+ ++S P +P + P P + A SP
Sbjct: 2320 ---------ELKTPDVFKAPLTPRAS---QVEPQSPGLGLRPQEPPPAQALAPSPPSHPD 2367
Query: 1376 AFRQGSPT-----PALPEKRRMSVGDRAGSLPNYATINGKVSSPVASGMSSPSGGSTVS- 1429
FR GS T P L + + + +LP + + S AS S S S ++
Sbjct: 2368 IFRPGSYTDPYAQPPLTPRPQPPPPESCCALPPRSLPSDPFSRVPASPQSQSSSQSPLTP 2427
Query: 1430 ---------FSHTLPDFSK---YSMPDNSPETR 1450
S P F YS P + P++R
Sbjct: 2428 RPLSAEAFCPSPVTPRFQSPDPYSRPPSRPQSR 2460
Score = 38.9 bits (89), Expect = 0.044
Identities = 80/343 (23%), Positives = 115/343 (33%), Gaps = 55/343 (16%)
Query: 964 PPPSGVRSPPGLAKTPLSALGLKPHNPADILLHPTGVTRR---RIQPEEDEGKVVVRLSE 1020
PP G P A P +G P PA + G + + + G++ ++L
Sbjct: 2107 PPQPGALGSPPPAAAPTIFIG-SPTTPAGLSTSADGFLKPPAGSVPGPDSPGELFLKLPP 2165
Query: 1021 EPRSYVESVARTAVAGPRAQDSEPKSFSAPATQAYGHEIPLRNGTLGGSFVSPSPLSTSS 1080
+ + V S +A A EP+ +AP T + SP+
Sbjct: 2166 QVPAQVPSQDPFGLAP--AYPLEPRFPTAPPTYP--------------PYPSPTGAPAQP 2209
Query: 1081 PILSADSTSVGSFPSGESSDQGPRTPT-QPLLESGFRS------GSLGQPSPSAQRNYQS 1133
P+L A S G+ GE P TP QP F +L P ++
Sbjct: 2210 PMLGASSRP-GAGQPGEFHTTPPGTPRHQPSTPDPFLKPRCPSLDNLAVPESPGVGGGKA 2268
Query: 1134 SSPL---PTVGSSY------------SSPDYSLQH--FSSSPESQARA---QFSVAGVHT 1173
S PL P G S SSP Y + F SP S + V
Sbjct: 2269 SEPLLSPPPFGESRKALEVKKEELGASSPSYGPPNLGFVDSPSSGTHLGGLELKTPDVFK 2328
Query: 1174 VPGSPQARHRTVGTNTPPSPGFGWRAINPSMAAPSSPSLSHHQMMGPPGTGFHGSTVSSP 1233
P +P+A P SPG G R P A +PS H + PG+ + + P
Sbjct: 2329 APLTPRASQVE-----PQSPGLGLRPQEPPPAQALAPSPPSHPDIFRPGS--YTDPYAQP 2381
Query: 1234 QSSAATTPGSPSLCRHPAGVYQVSGLHNKVATTPGSPSLGRHP 1276
+ P P C S ++V +P S S + P
Sbjct: 2382 PLTPRPQPPPPESCCALPPRSLPSDPFSRVPASPQSQSSSQSP 2424
Score = 38.5 bits (88), Expect = 0.057
Identities = 98/408 (24%), Positives = 144/408 (35%), Gaps = 62/408 (15%)
Query: 640 REAVQRGLNSWQQQQQQQQQPRPPPRQQERAHLESLVASRPSPQPLAETPIPSLPEFPRA 699
++ +Q+ QQQQQQQQQ +QQ++ L + + SPQ + + P P A
Sbjct: 3945 QQQLQQQQQQLQQQQQQQQQQFQQQQQQQQMGLLNQSRTLLSPQQQQQQQVALGPGMP-A 4003
Query: 700 ASQQEIEQSIETLNMLMLDLEPASAAAPLHKSQSVPGAWPGASPLSSQPLS-GSSRQSHP 758
Q L+L + + P S+ A G S PL+ G++ +S
Sbjct: 4004 KPLQHFSSPGALGPTLLLTGKEQNTVDPAVSSE----ATEGPSTHQGGPLAIGTTPESMA 4059
Query: 759 LTQSRSGYIPSGHS---LGTPEPAPR-ASLESVPPGRSYSPYDYQPCL------AGPNQD 808
SG S L P+P P+ +SL+ PP R Q L Q
Sbjct: 4060 TEPGEVKPSLSGDSQLLLVQPQPQPQPSSLQLQPPLRLPGQQQQQVSLLHTAGGGSHGQL 4119
Query: 809 FHSKSPASSSLPAFL------------PTTHSPPGPQQPPASLP--GLTAQPLLSPKEAT 854
S +SS+P L T + GPQQP P T P
Sbjct: 4120 GSGSSSEASSVPHLLAQPSVSLGDQPGSMTQNLLGPQQPMLERPMQNNTGPQPPKPGPVL 4179
Query: 855 SDPSRTPEEEPLNLEGLVAHRVAGVQARE--------KQPAEPPAPLRRRAASDGQYENQ 906
P + G + ++ GV A+ +Q + A L +R Q Q
Sbjct: 4180 QSGQGLPGVGIMPTVGQLRAQLQGVLAKNPQLRHLSPQQQQQLQALLMQRQLQQSQAVRQ 4239
Query: 907 SPEATSPRSPGVRSPVQCV-----------SPELALTIALNPGGRPK-EPHLHSYKEAFE 954
+P P + SP+Q + P+ L G RP+ P L + A
Sbjct: 4240 TPPYQEPGTQ--TSPLQGLLGCQPQLGGFPGPQTGPLQELGAGPRPQGPPRLPAPPGALS 4297
Query: 955 --EMEGTSPSSPPPSGVRSP--PGLAKTPLSALGLKPHNPADILLHPT 998
+ G +PPPS + P P +P S L P + L PT
Sbjct: 4298 TGPVLGPVHPTPPPSSPQEPKRPSQLPSPSSQL------PTEAQLPPT 4339
Score = 37.0 bits (84), Expect = 0.17
Identities = 113/523 (21%), Positives = 175/523 (33%), Gaps = 102/523 (19%)
Query: 427 SATAALSPQEKREL-----DRLLSGFGLEREKQGAMYHTQHLRSRPAGGSAVPSSGRHVV 481
SA ALSP + L +LL G GL+ + LR P GG A+P
Sbjct: 3614 SAVLALSPSQSPRLLTKLPGQLLPGHGLQPPQGPPGGQAGGLRLTP-GGMALPGQ----- 3667
Query: 482 PAQVHVNGGALASERETDILDDELPNQDGHSAGSMGTLSSLDGVTNTSEGGYPEALSPLT 541
P +N ALA ++ Q HS G+ G+L+ G G +P L+ +
Sbjct: 3668 PGGPFLNT-ALAQQQ-----------QQQHSGGA-GSLAGPSG------GFFPGNLALRS 3708
Query: 542 NGLDKSYPMEPMVN--------GGGYPYESASRAGPAHAGHTAPMRPSYSAQEGLAGYQR 593
G D E + + + H ++ G+ Q
Sbjct: 3709 LGPDSRLLQERQLQLQQQRMQLAQKLQQQQQQQQQQQHLLGQVAIQQQQQQGPGVQTNQA 3768
Query: 594 EGPHPAWPQPVTTSHYA-----------HDPSGMFRSQSFSEAEPQLPPAPVRGGSSREA 642
GP P P +SH P GM + + Q P A G R+
Sbjct: 3769 LGPKPQGLMP-PSSHQGLLVQQLSPQPPQGPQGMLGPAQVAVLQQQHPGALGPQGPHRQV 3827
Query: 643 VQ---RGLNSWQ----------------QQQQQQQQPRPPPRQQERAHLESLVASRPSPQ 683
+ R L+S Q QQQQQQQQ + +HL+ + S
Sbjct: 3828 LMTQSRVLSSPQLAQQGQGLMGHRLVTAQQQQQQQQHQQQGSMAGLSHLQQSLMSHSGQP 3887
Query: 684 PLAETPIPSLPEFPRAAS-------QQEIEQSIETLNMLMLDLEPASAAAPLHKSQSVPG 736
L+ P+ SL + + QQ+ +Q ++ L + Q
Sbjct: 3888 KLSAQPMGSLQQLQQQQQLQQQQQLQQQQQQQLQQQQQLQQQQLQQQQQQQQLQQQQQQQ 3947
Query: 737 AWPGASPLSSQPLSGSSRQSHPLTQSRSGYIPSGHSLGTPEPAPRASLESVPPGRSYSPY 796
L Q + Q + G + +L +P+ + + ++ PG P
Sbjct: 3948 LQQQQQQLQQQQQQQQQQFQQQQQQQQMGLLNQSRTLLSPQQQQQQQV-ALGPGMPAKPL 4006
Query: 797 DY--QPCLAGP-----NQDFHSKSPASSSLPAFLPTTH---------------SPPGPQQ 834
+ P GP ++ ++ PA SS P+TH + PG +
Sbjct: 4007 QHFSSPGALGPTLLLTGKEQNTVDPAVSSEATEGPSTHQGGPLAIGTTPESMATEPGEVK 4066
Query: 835 PPASLPGLTAQPLLSPKEATSDPSRTPEEEPLNLEGLVAHRVA 877
P SL G +Q LL + PS + PL L G +V+
Sbjct: 4067 P--SLSG-DSQLLLVQPQPQPQPSSLQLQPPLRLPGQQQQQVS 4106
>gi|112734870 hypothetical protein LOC57648 [Homo sapiens]
Length = 1094
Score = 74.7 bits (182), Expect = 7e-13
Identities = 182/757 (24%), Positives = 250/757 (33%), Gaps = 166/757 (21%)
Query: 511 HSAGSMGTLSSLDGVTNTSEGGYPEALSPLTNGLDKSYPMEPMVNGGGYPYESASRAGPA 570
HS S +S DG T +S+GG P ++ S P GG S S A
Sbjct: 418 HSQSSDTIVS--DGSTLSSKGGSEG--QPESSTASNSVVPPPQ---GGSGRGSPSGGSTA 470
Query: 571 HAGHTAPMRPSYSAQEGLAGYQREGPHPAWPQPVTTSHYAHDPSGMFRSQSFSEAEPQLP 630
A T +R S G + R+ P P P +H H R + + LP
Sbjct: 471 EASDTLSIRSS-GQLSGRSVSLRKLKRP--PPPPRRTHSLHQ-----RGLAVPDGPLGLP 522
Query: 631 PAPVRGGSSREAVQRGLNSWQQQQQQQQQPRPPPRQQERAHLESLVASRPSPQPLAETPI 690
P P R +QQ Q PRPP + P P A + +
Sbjct: 523 PKPER------------------KQQPQLPRPPTTGGSEG-----AGAAPCPPNPANSWV 559
Query: 691 PSL--------PEFPR----AASQQEIEQSIETLNMLMLDLEPAS--AAAPLHKSQSVPG 736
P L P P +S + TL L PAS A P +
Sbjct: 560 PGLSPGGSRRPPRSPERTLSPSSGYSSQSGTPTLPPKGLAGPPASPGKAQPPKPERVTSL 619
Query: 737 AWPGASPLSSQPLSGSSRQSHPLTQSRSG---YIPSGHSLGTPEPAPRASLE-SVPPGRS 792
PGAS +SS S S S P RSG P G P P P+ S PP +
Sbjct: 620 RSPGAS-VSSSLTSLCSSSSDPAPSDRSGPQILTPLGDRFVIP-PHPKVPAPFSPPPSKP 677
Query: 793 YSPYDYQPCLAGPNQDFHSKSPASSSLPAFLPTTH-SPPGPQQPPASLPGLTAQPLLSPK 851
SP P LA P + +P + TT SP P P +L L P++S
Sbjct: 678 RSPNPAAPALAAP-----------AVVPGPVSTTDASPQSPPTPQTTLTPLQESPVISKD 726
Query: 852 EA---TSDPSRTPEEEPLNLEGLVAHRVAGVQAREK-------QPAEPPAPLRRRAA--- 898
++ + PS P P +V + + E+ P PPAP + +
Sbjct: 727 QSPPPSPPPSYHPPPPPTKKPEVVVEAPSASETAEEPLQDPNWPPPPPPAPEEQDLSMAD 786
Query: 899 ----SDGQYENQSPEATSPRSPGVRSPVQCVSPELALTIALNPGGRPKEPHLHSYKEAFE 954
+ + SPE P S A + + P G P P
Sbjct: 787 FPPPEEAFFSVASPEPAGPSGSPELVSSPAASSSSATALQIQPPGSPDPP---------- 836
Query: 955 EMEGTSPSSPPPSGVRSPPG-LAKTPLSALGLKPHNPADILLHPTGVTRRRIQPEEDEGK 1013
P+ P P+ S PG +AK P P G ++ P ED G
Sbjct: 837 ------PAPPAPAPASSAPGHVAKLPQK--------------EPVGCSKGGGPPREDVGA 876
Query: 1014 VVVRLSEEPRSYVESVARTAVAGPRAQDSEPKSFSAPATQAYGHEIPLRNGTLGGSFVSP 1073
+V S ++ V +V P + SAP + PLR G + P
Sbjct: 877 PLV-----TPSLLQMVRLRSVGAPGGAPTPALGPSAP-------QKPLRRALSGRASPVP 924
Query: 1074 SPLSTSSPILSADSTSVGSFPSGESSDQ-------GPRTPTQP------LLESGFRSGSL 1120
+P S + + S+ + G SS Q PR P P + G R L
Sbjct: 925 APSSGLHAAVRLKACSLAA-SEGLSSAQPNGPPEAEPRPPQSPASTASFIFSKGSRKLQL 983
Query: 1121 GQP-SPSAQRNYQSSSPLPTVGSSYSSPDYSLQHFSSSPESQARAQFSVAGVHTVPGSPQ 1179
+P SP Q + Q + S P + + +P P
Sbjct: 984 ERPVSPETQADLQRNLVAELRSISEQRPPQAPKKSPKAP------------------PPV 1025
Query: 1180 ARHRTVGTNTPPSPGFGWRAINPSMAAPSSPSLSHHQ 1216
AR +VG P SP + RA + AP + L H Q
Sbjct: 1026 ARKPSVGVPPPASPSYP-RA--EPLTAPPTNGLPHTQ 1059
Score = 40.0 bits (92), Expect = 0.020
Identities = 160/694 (23%), Positives = 230/694 (33%), Gaps = 121/694 (17%)
Query: 799 QPCLAGPNQDFHSKSPASSSLPAFLPTTHSPPGPQQPPASLPGLTAQPLLS-PKEATSDP 857
Q GP++D S ++S A T + G T +P S PK S
Sbjct: 154 QSSRTGPDEDNISFCSQTTSYVAESSTAEDALSIRSEMIQRKGSTFRPHDSFPKSGKS-- 211
Query: 858 SRTPEEEPLNLEGLVAH--RVAGVQAREKQPAEPPAPLRRRAASDGQYENQSPEATSPRS 915
R E + GL H + G++ + P P AP R A + + P TS
Sbjct: 212 GRRRRERRSTVLGLPQHVQKELGLRNEREAPGTPRAPGARDAVRIPTVDGR-PRGTS--G 268
Query: 916 PGVRSPVQCVSPELALTIALNPGGRPKEPHLHSYKEAFEEMEGTSPSSPPPSGVRSPPGL 975
G R +Q + E G E L + + + S +G R+PP
Sbjct: 269 MGARVSLQALEAEAE-------AGAETEAMLQRHIDRVYRDDTFVGRS---TGTRAPPLT 318
Query: 976 AKTPLSALGL-------KPHNPADILLHPTGVTRRRIQPEE---------DEGKVVVRL- 1018
L+ GL +P +PA + + P ++ P G+ +R
Sbjct: 319 RPMSLAVPGLTGGAGPAEPLSPA-MSISPQATYLSKLIPHAVLPPTVDVVALGRCSLRTL 377
Query: 1019 ------SEEPRSYVESVAR-TAVAGPRAQDSEPKSFSAPATQAYGHEIPLRNGTL----G 1067
S P S V S+ R ++V+ P+ + P S S + + + + +G+ G
Sbjct: 378 SRCSLHSASPAS-VRSLGRFSSVSSPQPRSRHPSSSSDTWSHSQSSDTIVSDGSTLSSKG 436
Query: 1068 GSFVSPSPLSTSSPILSADSTSVG-SFPSGESSDQG------------------------ 1102
GS P + S+ ++ G PSG S+ +
Sbjct: 437 GSEGQPESSTASNSVVPPPQGGSGRGSPSGGSTAEASDTLSIRSSGQLSGRSVSLRKLKR 496
Query: 1103 ---PRTPTQPLLESGFR--SGSLGQPSPSAQRNYQSSSPLP-TVGSSYSSPDYSLQHFSS 1156
P T L + G G LG P P +R Q P P T G S +
Sbjct: 497 PPPPPRRTHSLHQRGLAVPDGPLGLP-PKPERKQQPQLPRPPTTGGSEGA---GAAPCPP 552
Query: 1157 SPESQARAQFSVAGVHTVPGSPQARHRTV----------GTNTPPSPGFGWRAINPSMAA 1206
+P + S G P SP+ RT+ GT T P G +P A
Sbjct: 553 NPANSWVPGLSPGGSRRPPRSPE---RTLSPSSGYSSQSGTPTLPPKGLAGPPASPGKAQ 609
Query: 1207 PSSPSLSHHQMMGPPGTGFHGSTVSSPQSSAATTPGSPS--LCRHPAGVYQVSGLHNKV- 1263
P P + PG S S SS+ P S P G V H KV
Sbjct: 610 PPKPE--RVTSLRSPGASVSSSLTSLCSSSSDPAPSDRSGPQILTPLGDRFVIPPHPKVP 667
Query: 1264 ATTPGSPSLGRHPGAHQGNLAS-----GLHSNAIASPGSPSLGRHLGGSGSVVPGSPCLD 1318
A PS R P LA+ G S ASP SP + + + + SP +
Sbjct: 668 APFSPPPSKPRSPNPAAPALAAPAVVPGPVSTTDASPQSPPTPQT---TLTPLQESPVIS 724
Query: 1319 RHVAYGGYSTPEDRRPTLSRQSSASGYQAPST----------PSFPVSPAYYPGLS--SP 1366
+ + P P + +APS P++P P P S
Sbjct: 725 KDQSPPPSPPPSYHPPPPPTKKPEVVVEAPSASETAEEPLQDPNWPPPPPPAPEEQDLSM 784
Query: 1367 ATSPSPDSAAFRQGSPTPALPEKRRMSVGDRAGS 1400
A P P+ A F SP PA P V A S
Sbjct: 785 ADFPPPEEAFFSVASPEPAGPSGSPELVSSPAAS 818
Score = 33.9 bits (76), Expect = 1.4
Identities = 46/168 (27%), Positives = 57/168 (33%), Gaps = 17/168 (10%)
Query: 1284 ASGLHSNAIASPGSPSLGRHLGGSGSVVPGSPCLD--RHVAYGGYSTPEDRRP------- 1334
++G + + P S ++ GG+G P SP + Y P P
Sbjct: 309 STGTRAPPLTRPMSLAVPGLTGGAGPAEPLSPAMSISPQATYLSKLIPHAVLPPTVDVVA 368
Query: 1335 -------TLSRQSSASGYQAPSTPSFPVSPAYYPGLSSPATSPSPDSAAFRQGSPTPALP 1387
TLSR S S A S P S S S D+ + Q S T
Sbjct: 369 LGRCSLRTLSRCSLHSASPASVRSLGRFSSVSSPQPRSRHPSSSSDTWSHSQSSDTIVSD 428
Query: 1388 EKRRMSVGDRAGSLPNYATINGKVSSPVA-SGMSSPSGGSTVSFSHTL 1434
S G G + N V P SG SPSGGST S TL
Sbjct: 429 GSTLSSKGGSEGQPESSTASNSVVPPPQGGSGRGSPSGGSTAEASDTL 476
>gi|239743293 PREDICTED: mucin 12 [Homo sapiens]
Length = 5478
Score = 74.3 bits (181), Expect = 9e-13
Identities = 278/1210 (22%), Positives = 414/1210 (34%), Gaps = 224/1210 (18%)
Query: 370 KKKDSLHGSTGAVN-ATRPTLSATPNHVEHTLSVSSDSGNSTASTKTDKTDEPVPGASSA 428
++ ++H S GA A PT SAT V + SG++ + T S
Sbjct: 1633 EESTTVHSSPGATGTALFPTRSATSVLVGEPTTSPISSGSTETTALPGSTTTAGLSEKST 1692
Query: 429 TAALSPQEKRELDRLLSGFGLEREKQGAMYHTQHLRSRPAGGSAVPSSGRHVVPAQVHVN 488
T SP R D LS T H SRP G +P V+
Sbjct: 1693 TFYSSP---RSPDTTLSPASTTSSGVSEESTTSH--SRPGSTHTTAFPGSTTMPG---VS 1744
Query: 489 GGALASERETDILDDELPNQDGHSAGSMGTLSSLDGVTNTSEGGYPEALSP---LTNGLD 545
+ AS D L + +A S+G S+ ++S G L P +GL
Sbjct: 1745 QESTASHSSPGSTDTTL-SPGSTTASSLGPEST---TFHSSPGSTETTLLPDNTTASGLL 1800
Query: 546 KSYPMEPMVNGGGYPYESASRAGPA-HAGHTAPMRPSYSAQEGLAGYQREGPHPAWPQPV 604
++ P+ + G P+ + S AG G + + S+++ + P P
Sbjct: 1801 EA--STPVHSSTGSPHTTLSPAGSTTRQGESTTFQSWPSSKDTM------------PAPP 1846
Query: 605 TTSHYAHDPSGMFRSQSFSEAEPQLPPAPVRGGSSREAVQRGLNSWQQQQQQQQQPRPPP 664
TT+ S + S P P SS + ++ P P
Sbjct: 1847 TTT------SAFVELSTTSHGSPSSTPTTHFSASSTTLGRSEESTTVHSSPVATATTPSP 1900
Query: 665 RQQERAHL-ESLVASRPSPQPLAETPIPSLPEFPRAASQQEIEQSIETLNMLMLDLEPAS 723
+ + L E A SP T PE A+ + E ++ + + P++
Sbjct: 1901 ARSTTSGLVEESTAYHSSP---GSTQTMHFPESSTASGRSEESRTSHSSTTHTISSPPST 1957
Query: 724 AAAPLHKSQSVPGAWPGASPLSSQPLSGS-SRQSHPLTQSRSGYIPSGHSL--------- 773
+A + + S + PG++ + P S + S +S T S S +G +
Sbjct: 1958 TSALVEEPTSYHSS-PGSTATTHFPDSSTTSGRSEESTASHSSQDATGTIVLPARSTTSV 2016
Query: 774 ----GTPEPAPRASLESVP-PGRSYSPYDYQPCLAGPNQDFHS--KSPASSSLPAFLP-- 824
T P S+E+ PG + +P L+ + FHS +SPA++ PA
Sbjct: 2017 LLGESTTSPISSGSMETTALPGSTTTPG-----LSEKSTTFHSSPRSPATTLSPASTTSS 2071
Query: 825 -------TTHSPPGPQQPPASLPGLTAQPLLSPKEATSD-----------PSRTPEEEPL 866
T+HS PG A P T P LS TS P+ T P
Sbjct: 2072 GVSEESTTSHSRPGSTHTTA-FPDSTTTPGLSRHSTTSHSSPGSTDTTLLPASTTTSGP- 2129
Query: 867 NLEGLVAHRVAGVQAREKQPAEPPAPLRRRAASDGQYE---NQSPEAT-------SPRSP 916
+ E +H G P A S GQ + SP +T S S
Sbjct: 2130 SQESTTSHSSPGSTDTALSPGSTTA------LSFGQESTTFHSSPGSTHTTLFPDSTTSS 2183
Query: 917 G-VRSPVQCVSPELALTIALNPGGRPKEPHLHSYKEAFEEMEGTSPSSP-PPSGVRSPPG 974
G V + + S + L+P P L AF+ ++ ++P PPS +P
Sbjct: 2184 GIVEASTRVHSSTGSPRTTLSPASSTS-PGLQGESTAFQTHPASTHTTPSPPSTATAPVE 2242
Query: 975 LAKTPLSALGLKP------------HNPADILLH---------PTGV----------TRR 1003
+ T + G P H+ + H P+ T
Sbjct: 2243 ESTTYHRSPGSTPTTHFPASSTTSGHSEKSTIFHSSPDASGTTPSSAHSTTSGRGESTTS 2302
Query: 1004 RIQPEEDEGKVVVRLSEEPRSYVESVARTAVAGPRAQDSEPKSFSAPATQA---YGHEIP 1060
RI P E + + P + + T + PR+ P + +PA+ G E
Sbjct: 2303 RISPGSTEITTLPGSTTTPG--LSEASTTFYSSPRS----PTTTLSPASMTSLGVGEEST 2356
Query: 1061 LRNGTLGGSFVSPSPLSTSSPILSADSTSV-GSFPSGESSDQGPRTP------------- 1106
G + + SP ST++P LS +ST+V S P + PRTP
Sbjct: 2357 TSRSQPGSTHSTVSPASTTTPGLSEESTTVYSSSPGSTETTVFPRTPTTSVRGEEPTTFH 2416
Query: 1107 -----------TQPLLESGFRSGSLGQP-SPSAQRN-----------YQSSSPLPTVGSS 1143
T+ SG S P SP++ + + S+ P+ S
Sbjct: 2417 SRPASTHTTLFTEDSTTSGLTEESTAFPGSPASTQTGLPATLTTADLGEESTTFPSSSGS 2476
Query: 1144 YS---SPDYSLQHFSSSPESQARAQFSVAGVHTVPGSPQ----ARHRTVGTNTPPSPGFG 1196
SP S + +R S T+PGSP + T +P SP
Sbjct: 2477 TGTTLSPARSTTSGLVGESTPSRLSPSSTETTTLPGSPTTPSLSEKSTTFYTSPRSPDAT 2536
Query: 1197 WR-AINPSMAAPSSPSLSHHQMMGPPGTGFHGSTVSSPQSSAATT----PGSPSLCRHPA 1251
A S S SH Q T F ST + S +TT PGS PA
Sbjct: 2537 LSPATTTSSGVSEESSTSHSQPGSTHTTAFPDSTTTPGLSRHSTTSHSSPGSTDTTLLPA 2596
Query: 1252 GVYQVSGLHNKVAT---TPGSPSLGRHPGAHQGNLASGLHSNAI-ASPGS--PSLGRHLG 1305
SG + T +PGS PG+ L+ G S +SPGS +L
Sbjct: 2597 ST-TTSGPSQESTTSHSSPGSTDTALSPGSTTA-LSFGQESTTFHSSPGSTHTTLFPDST 2654
Query: 1306 GSGSVVPGSPCLDRHVAYGGYSTPEDRRPTLSRQSSAS-GYQAPST--PSFPVSPAYYPG 1362
S +V S + +S+ R TLS SS S G Q ST + P S P
Sbjct: 2655 TSSGIVEASTRV--------HSSTGSPRTTLSPASSTSPGLQGESTTFQTHPASTHTTPS 2706
Query: 1363 LSSPATSPSPDSAAFRQ---GSPTPALPEKRRMSVGDRAGSLPNYATINGKVSSPVASGM 1419
S AT+P +S + + +PT P S ++ + SSP ASG
Sbjct: 2707 PPSTATAPVEESTTYHRSPGSTPTTHFPASSTTSGHSEKSTIFH--------SSPDASGT 2758
Query: 1420 SSPSGGSTVS 1429
+ S ST S
Sbjct: 2759 TPSSAHSTTS 2768
Score = 63.5 bits (153), Expect = 2e-09
Identities = 229/1059 (21%), Positives = 344/1059 (32%), Gaps = 125/1059 (11%)
Query: 356 HTQGPLDGSLYAKVKKKDSLHGSTGAVNATR-PTLSATPNHVEH-TLSVSSDSGNSTAST 413
HT + A V++ S H S G+ T P S T E T S SS T
Sbjct: 3506 HTISSAPSTTSALVEEPTSYHSSPGSTATTHFPDSSTTSGRSEESTASHSSQDATGTIVL 3565
Query: 414 KTDKTDEPVPGASSATAALS-PQEKRELDRLLSGFGLEREKQGAMYHTQHLRSRPAGGSA 472
T + G S+ + S E L + GL EK + + + ++
Sbjct: 3566 PARSTTSVLLGESTTSPISSGSMETTALPGSTTTPGLS-EKSTTFHSSPRSPATTLSPAS 3624
Query: 473 VPSSGRHVVPAQVHVNGGALASERETDILDDELPNQDGHSAGSMGTLSSLD-----GVTN 527
SSG H G+ + D P HS S + S D T
Sbjct: 3625 TTSSGVSEESTTSHSRPGSTHTTAFPD--STTTPGLSRHSTTSHSSPGSTDTTLLPASTT 3682
Query: 528 TSEGGYPEALSPLTNGLDKSYPMEPMVNGGGYPYESASRAGPAHAGHTAPMRPSYSAQEG 587
TS S ++G + + ES + + HT + P + G
Sbjct: 3683 TSGSSQESTTSHSSSGSTDTALSPGSTTALSFGQESTTFHSSPGSTHTT-LFPDSTTSSG 3741
Query: 588 LAGYQREGPHPAWPQPVTTSHYAHDPSGMFRSQSFS----EAEPQLPPAPVRGGSSREAV 643
+ H + P TT A S + +S + A P+P S+ A
Sbjct: 3742 IVEASTR-VHSSTGSPRTTLSPASSTSPGLQGESTAFQTHPASTHTTPSP---PSTATAP 3797
Query: 644 QRGLNSWQQQQQQQQQPRPPPRQQERAHLESLVASRPSPQPLAETPIPSLPEFPRAASQQ 703
++ + P H E SP TP + + +
Sbjct: 3798 VEESTTYHRSPGSTPTTHFPASSTTSGHSEKSTIFHSSPDASGTTPSSA-----HSTTSG 3852
Query: 704 EIEQSIETLNMLMLDLEPASAAAPLHKSQSVPGAWPGASPLSSQPLSGSSRQSHPLTQSR 763
E + ++ ++ L S + PG ++ S P S ++ S P + +
Sbjct: 3853 RGESTTSRIS------PGSTEITTLPGSTTTPGLSEASTTFYSSPRSPTTTLS-PASMTS 3905
Query: 764 SGYIPSGHSLGTPEPAPRASLESVPPGRSYSPYDYQPCLAGPNQDFHSKSPASSSLPAFL 823
G G T P ++ +V P + + P L+ + +S SP S+ F
Sbjct: 3906 LGV---GEESTTSRSQPGSTHSTVSPASTTT-----PGLSEESTTVYSSSPGSTETTVFP 3957
Query: 824 PTTHSPPGPQQPPA--SLPGLTAQPLLSPKEATSDPSRTPEEEPLNLEGLVAHRVAGVQA 881
+T + ++P S P T L + TS + EE G A G+ A
Sbjct: 3958 RSTTTSVRREEPTTFHSRPASTHTTLFTEDSTTSGLT----EESTAFPGSPASTQTGLPA 4013
Query: 882 REKQPAEPPAPLRRRAASDGQYENQSPEATSPRSPGVRSPVQCVSPELALTIALNPGGRP 941
++S SP ++ S +SP T L G P
Sbjct: 4014 TLTTADLGEESTTFPSSSGSTGTKLSPARSTTSGLVGESTPSRLSPSSTETTTL--PGSP 4071
Query: 942 KEPHLHSYKEAFEEMEGTSPSSPPPSGVRSPPGLAKTPLSALGLKPHNPADILLHPTGVT 1001
P L F TSP S P SP + +S H+ G T
Sbjct: 4072 TTPSLSEKSTTFY----TSPRS--PDATLSPATTTSSGVSEESSTSHS-------QPGST 4118
Query: 1002 RRRIQPEEDEGKVVVRLSEEPRSYVESVARTAVAGPRAQDSEPKSFSAPATQAYGHEIPL 1061
P + LS+EP + S S AT + G
Sbjct: 4119 HTTAFP---DSTTTSGLSQEPTT-----------------SHSSQGSTEATLSPGSTTAS 4158
Query: 1062 RNGTLGGSFVSPSPLSTSSPILSADSTSVGSFPSGESSDQGPRTPTQPLLESGFRSGSLG 1121
G +F S SP T + +L D+ + G + + + L + S L
Sbjct: 4159 SLGQQSTTFHS-SPGDTETTLLPDDTITSGLVEASTPTHSSTGSLHTTLTPASSTSTGLQ 4217
Query: 1122 QPSPSAQRNYQSSSPLPTVGSSYSSPDYSLQHFSSSPESQARAQFSVAGVHTVPGSPQAR 1181
+ S + Q SS P+ S+ + P + S P S FS + T+ S ++
Sbjct: 4218 EESTTFQSWPSSSDTTPSPPSTTAVPVEVSTTYHSRPSSTPTTHFSASST-TLGRSEES- 4275
Query: 1182 HRTVGTNTPPSPGFGWRAINPSMAAPS----SPSLSHHQMMGPPGTGFHGSTVSSPQSSA 1237
T SPG A+ P+ +A S P+ S T GST ++ S
Sbjct: 4276 -----TTVHSSPGATGTALFPTRSATSVLVGEPTTSPISSGSTETTALPGSTTTAGLSEK 4330
Query: 1238 ATT----PGSPSLCRHPAGVYQVSGLHNKVATT---PGS------PSLGRHPGAHQGNLA 1284
+TT P SP PA SG+ + T+ PGS PS PG Q + A
Sbjct: 4331 STTFYSSPRSPDTTLSPASTTS-SGVSEESTTSHSRPGSMHTTAFPSSTTMPGVSQESTA 4389
Query: 1285 SGLHSNAIASPGSPSLGRHLGGSGSVVPGSPCLDRHVAYGGYSTPEDRRPTLSRQSSASG 1344
S HS SPGS G + + G H + G T L ++ASG
Sbjct: 4390 S--HS----SPGSTDTTLSPGSTTASSLGPESTTFHSSPGSTET-----TLLPDNTTASG 4438
Query: 1345 YQAPSTPSFPVSPAYYPGLSSPATSPSPDSAAFRQGSPT 1383
STP + SP T+ SP + RQG T
Sbjct: 4439 LLEASTP-------VHSSTGSPHTTLSPAGSTTRQGEST 4470
Score = 62.4 bits (150), Expect = 4e-09
Identities = 262/1169 (22%), Positives = 400/1169 (34%), Gaps = 224/1169 (19%)
Query: 369 VKKKDSLHGSTGAVNATRPTLSATPNHVEHTLSVSSDSGNSTASTKTDKTDEPVPGASSA 428
V+ H STG+++ T S+T ++ + +S +D T P PG ++A
Sbjct: 1549 VEASTPTHSSTGSLHTTLTPASSTSAGLQEESTTFQSWPSS-----SDTTPSP-PGTTAA 1602
Query: 429 TAALSPQEKRELDRLLSGFGLEREKQGAMYHTQHLRSRPAGGSAVPSS-GRHVVPAQVHV 487
+S YH++ + SA ++ GR VH
Sbjct: 1603 PVEVS----------------------TTYHSRPSSTPTTHFSASSTTLGRSEESTTVHS 1640
Query: 488 NGGA-----LASERETDILDDELPNQDGHSAGSMGTLSSLDGVTNTSEGGYPEALSPLTN 542
+ GA + T +L E P S+GS T ++L G T T+ G ++ + ++
Sbjct: 1641 SPGATGTALFPTRSATSVLVGE-PTTSPISSGSTET-TALPGSTTTA-GLSEKSTTFYSS 1697
Query: 543 GLDKSYPMEP-MVNGGGYPYESASRAGPAHAGHTAPMRPSYS----AQEGLAGYQREGPH 597
+ P G ES + + HT S + +QE A + G
Sbjct: 1698 PRSPDTTLSPASTTSSGVSEESTTSHSRPGSTHTTAFPGSTTMPGVSQESTASHSSPGST 1757
Query: 598 PAWPQPVTTSHYAHDP-SGMFRSQSFSEAEPQLP-----------PAPVR---------- 635
P +T+ + P S F S S LP PV
Sbjct: 1758 DTTLSPGSTTASSLGPESTTFHSSPGSTETTLLPDNTTASGLLEASTPVHSSTGSPHTTL 1817
Query: 636 ---GGSSREAVQRGLNSWQQQQQQQQQPRPPPRQQERAHLESLVASRPSPQPLAETPIPS 692
G ++R+ SW + P P A +E S SP S
Sbjct: 1818 SPAGSTTRQGESTTFQSWPSSKDTM----PAPPTTTSAFVELSTTSHGSPS--------S 1865
Query: 693 LPEFPRAASQQEIEQSIETLNMLMLDLEPASAAAPLHKSQS---VPGAWPGASPLSSQPL 749
P +AS + +S E+ + + A+ +P + S +SP S+Q +
Sbjct: 1866 TPTTHFSASSTTLGRSEESTTVHSSPVATATTPSPARSTTSGLVEESTAYHSSPGSTQTM 1925
Query: 750 --SGSSRQSHPLTQSRSGYIPSGHSLGTPEPAPRASLESVPPGRSYSPYDYQPCLAGPNQ 807
SS S +SR+ + + H++ +P P+ ++L P
Sbjct: 1926 HFPESSTASGRSEESRTSHSSTTHTISSP-PSTTSALVEEP------------------T 1966
Query: 808 DFHSKSPASSSLPAFLPTTHSPPGPQQPPASLPGLTAQPLLSPKEATSD---PSRTPEEE 864
+HS SP S++ TTH P S + S ++AT P+R+
Sbjct: 1967 SYHS-SPGSTA------TTHFPDSSTTSGRSEESTASH---SSQDATGTIVLPARSTTSV 2016
Query: 865 PLNLEGLVAHRVAGVQAREKQPAEPPAPLRRRAASDGQYENQSPEATSPRSPGVR-SPVQ 923
L E + +G P P G E + +SPRSP SP
Sbjct: 2017 LLG-ESTTSPISSGSMETTALPGSTTTP--------GLSEKSTTFHSSPRSPATTLSPAS 2067
Query: 924 CVS---PELALTIALNPGGRPKEPHLHSYKEAFEEMEGTSPSSPPPSGVRSPPGLAKT-- 978
S E + T PG ++ AF + T S + S PG T
Sbjct: 2068 TTSSGVSEESTTSHSRPGS--------THTTAFPDSTTTPGLSRHSTTSHSSPGSTDTTL 2119
Query: 979 -PLSALGLKPHNPADILLHPTGVTRRRIQPEEDEGKVVVRLSEEPRSYVESVARTAVAGP 1037
P S P + G T + P + +E ++ S T
Sbjct: 2120 LPASTTTSGPSQESTTSHSSPGSTDTALSP---GSTTALSFGQESTTFHSSPGSTHTT-- 2174
Query: 1038 RAQDSEPKSFSAPATQAYGHEIPLRNGTLGGSFVSPSPLSTSSPILSADSTSVGSFP-SG 1096
DS S A+ + + G + SP S++SP L +ST+ + P S
Sbjct: 2175 LFPDSTTSSGIVEASTRV-------HSSTGSPRTTLSPASSTSPGLQGESTAFQTHPAST 2227
Query: 1097 ESSDQGPRTPTQPLLESGFRSGSLGQ------PSPSAQRNYQSSSPLPTVGSSYSSPDYS 1150
++ P T T P+ ES S G P+ S + S + +SSPD
Sbjct: 2228 HTTPSPPSTATAPVEESTTYHRSPGSTPTTHFPASSTTSGHSEKSTI-----FHSSPD-- 2280
Query: 1151 LQHFSSSPESQARAQFSVAGVHTVPG-SPQARHRTVGTNTPPSPGFGWRAINPSMAAPSS 1209
S + S A + S G T SP + T + +PG A ++P S
Sbjct: 2281 ---ASGTTPSSAHSTTSGRGESTTSRISPGSTEITTLPGSTTTPGLS-EASTTFYSSPRS 2336
Query: 1210 P--SLSHHQM----MGPPGTGFH---GSTVSSPQSSAATTPGSPSLCRHPAGVYQVSGLH 1260
P +LS M +G T GST S+ ++ TTPG L VY S
Sbjct: 2337 PTTTLSPASMTSLGVGEESTTSRSQPGSTHSTVSPASTTTPG---LSEESTTVYSSSPGS 2393
Query: 1261 NKVATTPGSPSL---GRHPGAH-------------QGNLASGLHSNAIASPGSPSLGRHL 1304
+ P +P+ G P + + SGL + A PGSP+
Sbjct: 2394 TETTVFPRTPTTSVRGEEPTTFHSRPASTHTTLFTEDSTTSGLTEESTAFPGSPA----- 2448
Query: 1305 GGSGSVVPGSPCLDRHVAYGGYSTPEDRRPTLSRQSSASGYQAPSTPSFPVSPAYYPGLS 1364
S G P G ST P+ S + + A ST S V G S
Sbjct: 2449 ----STQTGLPATLTTADLGEEST---TFPSSSGSTGTTLSPARSTTSGLV------GES 2495
Query: 1365 SPA-TSPSPDSAAFRQGSP-TPALPEKRR---MSVGDRAGSLPNYATINGKVSSPVASGM 1419
+P+ SPS GSP TP+L EK S +L T + VS ++
Sbjct: 2496 TPSRLSPSSTETTTLPGSPTTPSLSEKSTTFYTSPRSPDATLSPATTTSSGVSEESSTSH 2555
Query: 1420 SSPSGGSTVSF--SHTLPDFSKYSMPDNS 1446
S P T +F S T P S++S +S
Sbjct: 2556 SQPGSTHTTAFPDSTTTPGLSRHSTTSHS 2584
Score = 61.6 bits (148), Expect = 6e-09
Identities = 260/1176 (22%), Positives = 377/1176 (32%), Gaps = 180/1176 (15%)
Query: 375 LHGSTGAVNATRPTLSATPNHVEHTLSVSSDSGNSTASTKTDKTDEPVPGASSATAALSP 434
+H STG+ + T S+T + E T S S T+ + T V S T SP
Sbjct: 395 VHSSTGSPHTTLSPSSSTTHEGEPTTFQSWPSSKDTSPAPSGTTSAFV--KLSTTYHSSP 452
Query: 435 QEKRELDRLLSGFGLEREKQGAMYHTQHLRSRPAGGSAVPSSGRHVVPAQVHVNGGALAS 494
S L ++ H S P + P R V + S
Sbjct: 453 SSTPTTHFSASSTTLGHSEESTPVH-----SSPVATATTPPPARSATSGHVEESTAYHRS 507
Query: 495 ERETDILD-DELPNQDGHSAGSMGTLSSLDGVTNTSEGGYPEALSPLTNGLDKSYPMEPM 553
T + E GHS S ++ G T ++ P + L + S
Sbjct: 508 PGSTQTMHFPESSTTSGHSEES----ATFHGSTTHTKSSTPSTTAALAHTSYHSSLGSTE 563
Query: 554 VNGGGYPYESASRAGPAHAGHTAP------MRPSYSAQEGLAGYQREGPHPAWPQPV--- 604
+ R+ + A H++P + P+ S L G P +
Sbjct: 564 TTHFRDSSTISGRSEESKASHSSPDAMATTVLPAGSTPSVLVGDSTPSPISSGSMETTAL 623
Query: 605 ---TTSHYAHDPSGMFRSQSFSEAEPQLPPAPVRGGSSREAVQRGLNSWQQQQQQQQQPR 661
TT + S F S S LP + G S E+ S +
Sbjct: 624 PGSTTKPGLSEKSTTFYSSPRSPDTTHLPASMTSSGVSEEST----TSHSRPGSTHTTAF 679
Query: 662 PPPRQQERAHLESLVASRPSPQPLAETPIPSL-------PEFPRAASQQEIEQSIETLNM 714
P ES AS SP P T P PE+ S+ T
Sbjct: 680 PGSTTMPGLSQES-TASHSSPGPTDTTLSPGSTTASSLGPEYTTFHSRPG-----STETT 733
Query: 715 LMLDLEPAS----AAAPLHKSQSVPGAWPGASPLSSQPLSGSSRQSH-----------PL 759
L+ D AS A+ P+H S P SP S G S H P
Sbjct: 734 LLPDNTTASGLLEASMPVHSSTRSPHT--TLSPAGSTTRQGESTTFHSWPSSKDTRPAPP 791
Query: 760 TQSRSGYIPSGHSLGTPE--PAPRASLESVPPGRSYSPYDYQPCLAGPNQDFH-SKSPAS 816
T + + PS S G+P P S S G Y G Q H +S +
Sbjct: 792 TTTSAFVEPSTTSHGSPSSIPTTHISARSTTSGLVEESTTYHSS-PGSTQTMHFPESDTT 850
Query: 817 SSLPAFLPTTHSPPGPQQPPASLPGLTAQPLLSPKEATSDPSRT-----PEEEPL---NL 868
S T+HS +S P T+ + P S P T P+ +
Sbjct: 851 SGRGEESTTSHS--STTHTISSAPSTTSALVEEPTSYHSSPGSTATTHFPDSSTTSGRSE 908
Query: 869 EGLVAHRVAGVQAREKQPAEPPAPLRRRAASDGQYENQSPEAT----SPRSPGV--RSPV 922
E +H PA + ++ + S E T S +PG+ RS
Sbjct: 909 ESTASHSSQDATGTIVLPARSTTSVLLGESTTSPISSGSMETTALPGSTTTPGLSERSTT 968
Query: 923 QCVSPELALTIALNPGGRPKEPHLHSYKEAFEEMEGTSPSSPPPSGVRSPPGLAKTP-LS 981
SP T L+P + E TS S P + + P TP LS
Sbjct: 969 FHSSPRSPAT-TLSPAS--------TTSSGVSEESTTSRSRPGSTHTTAFPDSTTTPGLS 1019
Query: 982 ALGLKPHN---PADILLHP-----TGVTRRRIQPEEDEGKVVVRLSEEPRSYVESVARTA 1033
H+ D L P +G ++ G LS + + +
Sbjct: 1020 RHSTTSHSSPGSTDTTLLPASTTTSGPSQESTTSHSSSGSTDTALSPGSTTALSFGQEST 1079
Query: 1034 VAGPRAQDSEPKSFSAPATQAYGHEIPLR-NGTLGGSFVSPSPLSTSSPILSADSTSVGS 1092
+ F T + E R + + G + SP S++SP L +ST+ +
Sbjct: 1080 TFHSNPGSTHTTLFPDSTTSSGIVEASTRVHSSTGSPRTTLSPASSTSPGLQGESTAFQT 1139
Query: 1093 FP-SGESSDQGPRTPTQPLLESGFRSGSLGQ------PSPSAQRNYQSSSPLPTVGSSYS 1145
P S ++ P T T P+ ES S G P+ S + S + +S
Sbjct: 1140 HPASTHTTPSPPSTATAPVEESTTYHRSPGSTPTTHFPASSTTSGHSEKSTI-----FHS 1194
Query: 1146 SPDYSLQHFSSSPESQARAQFSVAGVHTVPG-SPQARHRTVGTNTPPSPGFGWRAINPSM 1204
SPD S + S A + S G T SP + T + +PG A
Sbjct: 1195 SPD-----ASGTTPSSAHSTTSGRGESTTSRISPGSTEITTLPGSTTTPGLS-EASTTFY 1248
Query: 1205 AAPSSP--SLSHHQM----MGPPGTGFH---GSTVSSPQSSAATTPGSPSLCRHPAGVYQ 1255
++P SP +LS M +G T GST S+ ++ TTPG L VY
Sbjct: 1249 SSPRSPTTTLSPASMTSLGVGEESTTSRSQPGSTHSTVSPASTTTPG---LSEESTTVYS 1305
Query: 1256 VS---------------GLHNKVATTPGSPSLGRHPGAH-QGNLASGLHSNAIASPGSPS 1299
S +H + TT S H + + SGL + A PGSP+
Sbjct: 1306 SSRGSTETTVFPHSTTTSVHGEEPTTFHSRPASTHTTLFTEDSTTSGLTEESTAFPGSPA 1365
Query: 1300 LGR----------HLGGSGSVVPG---------SPCLDRHVAYGGYSTPEDRRPTLSRQS 1340
+ LG + P SP G STP P+ + +
Sbjct: 1366 STQTGLPATLTTADLGEESTTFPSSSGSTGTKLSPARSTTSGLVGESTPSRLSPSSTETT 1425
Query: 1341 SASGYQAPSTPS-------FPVSPAYYPGLSSPATSPSPDSAAFRQGSPTPALPEKRRMS 1393
+ G +P+TPS F SP SPAT+ S S + S + + P +
Sbjct: 1426 TLPG--SPTTPSLSEKSTTFYTSPRSPDATLSPATTTS--SGVSEESSTSHSQPGSTHTT 1481
Query: 1394 VGDRAGSLPNYATINGKVSSPVASGMSSPSGGSTVS 1429
+ P+ T + P S S S +T+S
Sbjct: 1482 ------AFPDSTTTSDLSQEPTTSHSSQGSTEATLS 1511
Score = 58.5 bits (140), Expect = 5e-08
Identities = 255/1222 (20%), Positives = 402/1222 (32%), Gaps = 189/1222 (15%)
Query: 356 HTQGPLDGSLYAKVKKKDSLHGSTGAVNATR-PTLSATPNHVEHTLSVSSD--------- 405
HT + A V++ + H S G+ T P S T H E + S
Sbjct: 1145 HTTPSPPSTATAPVEESTTYHRSPGSTPTTHFPASSTTSGHSEKSTIFHSSPDASGTTPS 1204
Query: 406 SGNSTASTKTDKTDEPV-PGASSATAALSPQEKRELDRLLSGFGLEREKQGAMYHTQHLR 464
S +ST S + + T + PG++ T L + F +
Sbjct: 1205 SAHSTTSGRGESTTSRISPGSTEITTLPGSTTTPGLSEASTTFYSSPRSPTTTLSPASMT 1264
Query: 465 SRPAGGSAVPSSGRHVVPAQVHVNGGALASERETDILDDELPNQDGHSAGSMGTLSSLDG 524
S G + S + P H ++ T L +E S GS T
Sbjct: 1265 SLGVGEESTTSRSQ---PGSTHSTVSPASTT--TPGLSEESTTVYSSSRGSTETTVFPHS 1319
Query: 525 VTNTSEGGYPEALSPLTNGLDKSYPMEPMVNGGGYPYESASRAGPA--HAGHTAPMRPSY 582
T + G P + E G +A PA G A + +
Sbjct: 1320 TTTSVHGEEPTTFHSRPASTHTTLFTEDSTTSGLTEESTAFPGSPASTQTGLPATLTTAD 1379
Query: 583 SAQEGLAGYQREGPHPAWPQPV--TTSHYAHDPSGMFRSQSFSEAEPQLPPAPVRGGSSR 640
+E G P TTS + + S S +E LP +P S
Sbjct: 1380 LGEESTTFPSSSGSTGTKLSPARSTTSGLVGESTPSRLSPSSTETTT-LPGSPTTPSLSE 1438
Query: 641 EAVQRGLNSWQQQQQQQQQPRPPPRQQERAHLESLVASRPSPQPLAETPIPSLPEFPRAA 700
++ PR P A S S S ++ FP +
Sbjct: 1439 KSTTF-----------YTSPRSPDATLSPATTTSSGVSEESSTSHSQPGSTHTTAFPDST 1487
Query: 701 SQQEIEQSIETLNMLM----LDLEPASAAAPLHKSQSVP-GAWPGASPLSSQP----LSG 751
+ ++ Q T + L P S A QS + PG + + P SG
Sbjct: 1488 TTSDLSQEPTTSHSSQGSTEATLSPGSTTASSLGQQSTTFHSSPGDTETTLLPDDTITSG 1547
Query: 752 SSRQSHPLTQSRSGYIPSGHSLGTPEPAPRASL--ESVPPGRSYSPYDYQPCLAGPNQDF 809
S P T S +G + H+ TP + A L ES S D P G
Sbjct: 1548 LVEASTP-THSSTGSL---HTTLTPASSTSAGLQEESTTFQSWPSSSDTTPSPPGTTAAP 1603
Query: 810 HSKSPASSSLPAFLPTTH-----SPPGPQQPPASL---PGLTAQPLLSPKEATSDPSRTP 861
S S P+ PTTH + G + ++ PG T L + ATS P
Sbjct: 1604 VEVSTTYHSRPSSTPTTHFSASSTTLGRSEESTTVHSSPGATGTALFPTRSATSVLVGEP 1663
Query: 862 EEEPLNLEGLVAHRVAGVQAREKQPAEPPAPLRRRAASDGQYENQSPEATSPRSPGVR-S 920
P++ + G + G E + +SPRSP S
Sbjct: 1664 TTSPISSGSTETTALPG-----------------STTTAGLSEKSTTFYSSPRSPDTTLS 1706
Query: 921 PVQCVSPELALTIALNPGGRPKEPHLHSYKEAFEEMEGTSPSSPPPSGVRSPPGLAKTPL 980
P S ++ + RP H ++ + M G S S + S PG T L
Sbjct: 1707 PASTTSSGVSEE-STTSHSRPGSTHTTAFPGS-TTMPGVSQES---TASHSSPGSTDTTL 1761
Query: 981 SALGLKPHNPADILLHPTGVTRRRIQPEEDEGKVVVRLSEEPRSYVESVARTAVAGPRAQ 1040
S P T + PE + T + P +
Sbjct: 1762 S---------------PGSTTASSLGPE---------------------STTFHSSPGST 1785
Query: 1041 DSEPKSFSAPATQAYGHEIPLRNGTLGGSFVSPSPLSTSSPILSADSTSVGSFPSGESSD 1100
++ + A+ P+ + T G + SP +++ +ST+ S+PS + +
Sbjct: 1786 ETTLLPDNTTASGLLEASTPVHSST-GSPHTTLSPAGSTTR--QGESTTFQSWPSSKDTM 1842
Query: 1101 QGPRTPTQPLLESGFRSGSLGQPSPSAQRNYQSSSPLPTVG-SSYSSPDYSLQHFSSSPE 1159
P T T +E + S G PS + ++ +SS T+G S S+ +S +++
Sbjct: 1843 PAPPTTTSAFVE--LSTTSHGSPSSTPTTHFSASS--TTLGRSEESTTVHSSPVATATTP 1898
Query: 1160 SQARAQFS-----VAGVHTVPGSPQARHRTVGTNTPPSPGFGWRAINPSMAAPSSPSLSH 1214
S AR+ S H+ PGS Q H P S A S + +S S +
Sbjct: 1899 SPARSTTSGLVEESTAYHSSPGSTQTMH------FPESS----TASGRSEESRTSHSSTT 1948
Query: 1215 HQMMGPPGTGFHGSTVSSPQSSAATTPGSPSLCRHPAGVYQVSGLHNKVATTPGSPSLGR 1274
H + PP T S + +S ++PGS + P +TT G
Sbjct: 1949 HTISSPPST---TSALVEEPTSYHSSPGSTATTHFPDS-----------STTSGRSE--E 1992
Query: 1275 HPGAHQGNLASGLHSNAIASPGSPSLGRHLGGSGSVVPGSPCLDRHVAYGGYSTPEDRRP 1334
+H A+G I P + LG S + S ++ G +TP
Sbjct: 1993 STASHSSQDATG----TIVLPARSTTSVLLGESTTSPISSGSMETTALPGSTTTPG---- 2044
Query: 1335 TLSRQSSASGYQAPSTPSFPVSPA--YYPGLSSPATSP-----SPDSAAFRQGSPTPALP 1387
+ S + + +P +P+ +SPA G+S +T+ S + AF + TP L
Sbjct: 2045 --LSEKSTTFHSSPRSPATTLSPASTTSSGVSEESTTSHSRPGSTHTTAFPDSTTTPGL- 2101
Query: 1388 EKRRMSVGDRAGSLPNYATINGKVSSPVASGMSSPSGGSTVSFSHTLPDFSKYSMPDNSP 1447
R S + T+ P ++ S PS ST SH+ P + ++ SP
Sbjct: 2102 --SRHSTTSHSSPGSTDTTL-----LPASTTTSGPSQESTT--SHSSPGSTDTAL---SP 2149
Query: 1448 ETRAKVKFVQDTSKYWYKPEISREQAIALLKDQEPGAFIIRDS---HSFRGAYGLAMKVS 1504
+ + F Q+++ + P + L D + I+ S HS G+ + +
Sbjct: 2150 GSTTALSFGQESTTFHSSPGSTH---TTLFPDSTTSSGIVEASTRVHSSTGSPRTTLSPA 2206
Query: 1505 SPPPTIMQQNKKGDMTHELVRH 1526
S +Q TH H
Sbjct: 2207 SSTSPGLQGESTAFQTHPASTH 2228
Score = 57.4 bits (137), Expect = 1e-07
Identities = 175/750 (23%), Positives = 255/750 (34%), Gaps = 157/750 (20%)
Query: 721 PASAAAPLHKSQSV---PGAWPGASPLSSQPLSGSSRQSHPLTQS--RSGYIPSG-HSLG 774
P++A AP+ +S + PG+ P +S SG S +S S SG PS HS
Sbjct: 2708 PSTATAPVEESTTYHRSPGSTPTTHFPASSTTSGHSEKSTIFHSSPDASGTTPSSAHSTT 2767
Query: 775 -------TPEPAPRASLESVPPGRSYSPYDYQPCLAGPNQDFHS--KSPASSSLPAFLP- 824
T +P ++ + PG + +P L+ + F+S +SP ++ PA +
Sbjct: 2768 SGRGESTTSRISPGSTEITTLPGSTTTPG-----LSEASTTFYSSPRSPTTTLSPASMTS 2822
Query: 825 --------TTHSPPGPQQPPASLPGLTAQPLLSPKEATSDPSRTPEEEPLNLEGLVAHRV 876
T+ S PG S P T P LS + T S P + E V R
Sbjct: 2823 LGVGEESTTSRSQPGSTHSTVS-PASTTTPGLSEESTTVYSS-----SPGSTETTVFPRS 2876
Query: 877 AGVQAREKQP----AEPPAPLRRRAASDGQYENQSPEAT----SPRSPGVRSPVQCVSPE 928
R ++P + P + D + E+T SP S P + +
Sbjct: 2877 TTTSVRGEEPTTFHSRPASTHTTLFTEDSTTSGLTEESTAFPGSPASTQTGLPATLTTAD 2936
Query: 929 LALTIALNPGGRPKE-PHLHSYKEAFEEMEGTS-PSSPPPSGVRSP--PGLAKTPL---- 980
L P L + + G S PS PS + PG TP
Sbjct: 2937 LGEESTTFPSSSGSTGTTLSPARSTTSGLVGESTPSRLSPSSTETTTLPGSPTTPSLSEK 2996
Query: 981 -SALGLKPHNPADILLHPTGVTRRRIQPEED---------------EGKVVVRLSEEPRS 1024
+ P +P D L P T + E + LS+EP +
Sbjct: 2997 STTFYTSPRSP-DATLSPATTTSSGVSEESSTSHSQPGSTHTTAFPDSTTTSGLSQEPTA 3055
Query: 1025 YVESVART--------AVAGPRAQDSEPKSFSAPATQA------------YGHEIPLRNG 1064
S T A Q S S T+ P +
Sbjct: 3056 SHSSQGSTEATLSPGSTTASSLGQQSTTFHSSPGDTETTLLPDDTITSGLVEASTPTHSS 3115
Query: 1065 TLGGSFVSPSPLSTSSPILSADSTSVGSFPSGESSDQGPRTPTQPLLESGFRSGSLGQPS 1124
T G + +P S++S L +ST+ S+PS SSD P P G+ P
Sbjct: 3116 T-GSLHTTLTPASSTSAGLQEESTTFQSWPS--SSDTTPSPP-----------GTTAAPV 3161
Query: 1125 PSAQRNYQSSSPLPTVGSSYSSPDYSLQHFSSSPESQARAQFSVAGVHTVPGSPQARHRT 1184
+ + S PT HFS+S + R++ S VH+ PG+
Sbjct: 3162 EVSTTYHSRPSSTPTT------------HFSASSTTLGRSEESTT-VHSSPGA------- 3201
Query: 1185 VGTNTPPSPGFGWRAINPSMAAPS----SPSLSHHQMMGPPGTGFHGSTVSSPQSSAATT 1240
GT A+ P+ +A S P+ S T GST ++ S +TT
Sbjct: 3202 TGT-----------ALFPTRSATSVLVGEPTTSPISSGSTETTALPGSTTTAGLSEKSTT 3250
Query: 1241 ----PGSPSLCRHPAGVYQVSGLHNKVATT---PGSPSLGRHPGAHQGNLASGLHSNAIA 1293
P SP PA SG+ + T+ PGS PG+ G+ + A
Sbjct: 3251 FYSSPRSPDTTLSPASTTS-SGVSEESTTSHSRPGSTHTTAFPGS---TTMPGVSQESTA 3306
Query: 1294 SPGSPSLGRHLGGSGSVVPGSPCLDRHVAYGGYSTPEDRRPTLSRQSSASGYQAPSTPSF 1353
S SP GS S + + G + E L ++ASG STP
Sbjct: 3307 SHSSPGSTDTTLSPGSTTASSLGPESTTFHSGPGSTE--TTLLPDNTTASGLLEASTP-- 3362
Query: 1354 PVSPAYYPGLSSPATSPSPDSAAFRQGSPT 1383
+ SP T+ SP + RQG T
Sbjct: 3363 -----VHSSTGSPHTTLSPAGSTTRQGEST 3387
Score = 55.1 bits (131), Expect = 6e-07
Identities = 222/1085 (20%), Positives = 348/1085 (32%), Gaps = 181/1085 (16%)
Query: 510 GHSAGSMGTLSSLDGVTNTSEGGYPEALSPLTNGLDKSYPMEPMVNGGGYPYESASRAGP 569
G + S T SS D T S+ Y +++ +T + ++ N G + S +GP
Sbjct: 174 GGNTTSASTPSSSDPFTTFSD--YGVSVTFITGSTATKHFLDSSTNSGHSEESTVSHSGP 231
Query: 570 AHAGHTAPMRPSYSAQEGLAGYQREGPHPAWPQPVTTSHYAHDPSGMFRSQSFSEAEPQL 629
G T + PS+SA G + P + T L
Sbjct: 232 GATGTT--LFPSHSATSVFVGEPKTSPITSASMETTA----------------------L 267
Query: 630 PPAPVRGGSSREAVQRGLNSWQQQQQQQQQPRPPPRQQERAHLESLVASRPSPQPLAETP 689
P + G S ++ ++ + + P R E S P P
Sbjct: 268 PGSTTTAGLSEKST-----TFYSSPRSPDRTLSPARTTSSGVSEKSTTSHSRPGPTHTIA 322
Query: 690 IPSLPEFPRAASQQEIEQSIETLNMLMLD---LEPASAAAPLHKSQSVPGAWPGASPLSS 746
P P + + SI L P+S S PG +
Sbjct: 323 FPDSTTMPGVSQESTASHSIPGSTDTTLSPGTTTPSSLGPESTTFHSSPGYTKTTRLPDN 382
Query: 747 QPLSGSSRQSHPLTQSR-SGYIPSGHSLGTPEPAPRASLESVPPGRSYSPYDYQPCLAGP 805
SG S P+ S S + S T + +S P + D P +G
Sbjct: 383 TTTSGLLEASTPVHSSTGSPHTTLSPSSSTTHEGEPTTFQSWPSSK-----DTSPAPSGT 437
Query: 806 NQDFHSKSPASSSLPAFLPTTHSPPG--------PQQPPASLPGLTAQPLLSPKEATSDP 857
F S S P+ PTTH P S P TA +P A S
Sbjct: 438 TSAFVKLSTTYHSSPSSTPTTHFSASSTTLGHSEESTPVHSSPVATA---TTPPPARSAT 494
Query: 858 SRTPEEEPLNLEGLVAHRVAGVQAREKQPAEPPAPLRRRAASDGQYENQSPEATSPRSPG 917
S E E HR G P + + G E + S +
Sbjct: 495 SGHVE------ESTAYHRSPGSTQTMHFP--------ESSTTSGHSEESATFHGS--TTH 538
Query: 918 VRSPVQCVSPELALTIALNPGGRPKEPHLHSYKEAFEEMEGTSPSSPPPSGVRS---PPG 974
+S + LA T + G + H E + S P + + P G
Sbjct: 539 TKSSTPSTTAALAHTSYHSSLGSTETTHFRDSSTISGRSEESKASHSSPDAMATTVLPAG 598
Query: 975 LAKTPLSALGLKPHNP-ADILLHPTGVTRRRIQPEEDEGKVVVRLSEEPRSYVESVARTA 1033
TP +G +P + + T + +P LSE+ ++ S
Sbjct: 599 --STPSVLVGDSTPSPISSGSMETTALPGSTTKP---------GLSEKSTTFYSS----- 642
Query: 1034 VAGPRAQDSEPKSFSAPATQAYGHEIPLRNGTLGGSFVSPSPLSTSSPILSADSTSVGSF 1093
PR+ D+ S + E + G + + P ST+ P LS +ST+ S
Sbjct: 643 ---PRSPDTTHLPASM-TSSGVSEESTTSHSRPGSTHTTAFPGSTTMPGLSQESTASHSS 698
Query: 1094 PSGESSDQGPRTPTQPLL---------ESGFRSGSLGQPSPSAQRNYQSSSPLPTVGSSY 1144
P + P + T L G +L + +A ++S P V SS
Sbjct: 699 PGPTDTTLSPGSTTASSLGPEYTTFHSRPGSTETTLLPDNTTASGLLEASMP---VHSST 755
Query: 1145 SSPDYSLQHFSSSPESQARAQFSVAGVHTVPGSPQARHRTVGTNTPPSPGFGWRAINPSM 1204
SP H + SP Q H+ P S R P P + PS
Sbjct: 756 RSP-----HTTLSPAGSTTRQGESTTFHSWPSSKDTR--------PAPPTTTSAFVEPST 802
Query: 1205 AAPSSPS---------LSHHQMMGPPGTGFHGS-----TVSSPQSSAATTPGSPSLCRHP 1250
+ SPS S + T +H S T+ P+S + G S H
Sbjct: 803 TSHGSPSSIPTTHISARSTTSGLVEESTTYHSSPGSTQTMHFPESDTTSGRGEESTTSHS 862
Query: 1251 AGVYQVSGLHNKVA----------TTPGSPSLGRHP------GAHQGNLASGLHSNA--- 1291
+ + +S + + ++PGS + P G + + AS +A
Sbjct: 863 STTHTISSAPSTTSALVEEPTSYHSSPGSTATTHFPDSSTTSGRSEESTASHSSQDATGT 922
Query: 1292 IASPGSPSLGRHLGGSGSVVPGSPCLDRHVAYGGYSTPEDRRPTLSRQSSASGYQAPSTP 1351
I P + LG S + S ++ G +T P LS +S+ + + +P +P
Sbjct: 923 IVLPARSTTSVLLGESTTSPISSGSMETTALPGSTTT-----PGLSERST-TFHSSPRSP 976
Query: 1352 SFPVSPA--YYPGLSSPATSP-----SPDSAAFRQGSPTPALPEKRRMSVGDRAGSLPNY 1404
+ +SPA G+S +T+ S + AF + TP L R S +
Sbjct: 977 ATTLSPASTTSSGVSEESTTSRSRPGSTHTTAFPDSTTTPGL---SRHSTTSHSSPGSTD 1033
Query: 1405 ATINGKVSSPVASGMSSPSGGSTVSFSHTLPDFSKYSMPDNSPETRAKVKFVQDTSKYWY 1464
T+ P ++ S PS ST S S S + SP + + F Q+++ +
Sbjct: 1034 TTL-----LPASTTTSGPSQESTTSHSS-----SGSTDTALSPGSTTALSFGQESTTFHS 1083
Query: 1465 KPEISREQAIALLKDQEPGAFIIRDS---HSFRGAYGLAMKVSSPPPTIMQQNKKGDMTH 1521
P + L D + I+ S HS G+ + +S +Q TH
Sbjct: 1084 NPGSTH---TTLFPDSTTSSGIVEASTRVHSSTGSPRTTLSPASSTSPGLQGESTAFQTH 1140
Query: 1522 ELVRH 1526
H
Sbjct: 1141 PASTH 1145
Score = 54.7 bits (130), Expect = 8e-07
Identities = 248/1172 (21%), Positives = 384/1172 (32%), Gaps = 220/1172 (18%)
Query: 356 HTQGPLDGSLYAKVKKKDSLHGSTGAVNATR-PTLSATPNHVEHTLSVSSD--------- 405
HT + A V++ + H S G+ T P S T H E + S
Sbjct: 2702 HTTPSPPSTATAPVEESTTYHRSPGSTPTTHFPASSTTSGHSEKSTIFHSSPDASGTTPS 2761
Query: 406 SGNSTASTKTDKTDEPV-PGASSATAALSPQEKRELDRLLSGFGLEREKQGAMYHTQHLR 464
S +ST S + + T + PG++ T L + F +
Sbjct: 2762 SAHSTTSGRGESTTSRISPGSTEITTLPGSTTTPGLSEASTTFYSSPRSPTTTLSPASMT 2821
Query: 465 SRPAGGSAVPSSGRH------VVPAQVHVNGGALASERETDILDDELPNQDGHSAGSMGT 518
S G + S + V PA G SE T + P + T
Sbjct: 2822 SLGVGEESTTSRSQPGSTHSTVSPASTTTPG---LSEESTTVYSSS-PGSTETTVFPRST 2877
Query: 519 LSSLDGVTNTSEGGYPEAL-------SPLTNGLDK---SYPMEPMVNGGGYPYE------ 562
+S+ G T+ P + T+GL + ++P P G P
Sbjct: 2878 TTSVRGEEPTTFHSRPASTHTTLFTEDSTTSGLTEESTAFPGSPASTQTGLPATLTTADL 2937
Query: 563 -SASRAGPAHAGHTAP-MRPSYSAQEGLAGYQREGP-HPAWPQPVTTSHYAHDPSGMFRS 619
S P+ +G T + P+ S GL G P+ + T PS +S
Sbjct: 2938 GEESTTFPSSSGSTGTTLSPARSTTSGLVGESTPSRLSPSSTETTTLPGSPTTPSLSEKS 2997
Query: 620 QSFSEAEPQLPPAPVRGGSSREAVQRGLNSWQQQQQQQQQPRPPPRQQERAHLESLVASR 679
+F + P+ P A + S G++ Q P A +S S
Sbjct: 2998 TTFYTS-PRSPDATL---SPATTTSSGVSEESSTSHSQ-----PGSTHTTAFPDSTTTSG 3048
Query: 680 PSPQPLAETPIPSLPEFPRAASQQEIEQSIETLNMLMLDLEPASAAAPLHKSQSVP-GAW 738
S +P A +SQ E + L P S A QS +
Sbjct: 3049 LSQEPTASH-----------SSQGSTEAT----------LSPGSTTASSLGQQSTTFHSS 3087
Query: 739 PGASPLSSQP----LSGSSRQSHPLTQSRSGYIPSGHSLGTPEPAPRASL--ESVPPGRS 792
PG + + P SG S P T S +G + H+ TP + A L ES
Sbjct: 3088 PGDTETTLLPDDTITSGLVEASTP-THSSTGSL---HTTLTPASSTSAGLQEESTTFQSW 3143
Query: 793 YSPYDYQPCLAGPNQDFHSKSPASSSLPAFLPTTH-----SPPGPQQPPASL---PGLTA 844
S D P G S S P+ PTTH + G + ++ PG T
Sbjct: 3144 PSSSDTTPSPPGTTAAPVEVSTTYHSRPSSTPTTHFSASSTTLGRSEESTTVHSSPGATG 3203
Query: 845 QPLLSPKEATSDPSRTPEEEPLNLEGLVAHRVAGVQAREKQPAEPPAPLRRRAASDGQYE 904
L + ATS P P++ + G + G E
Sbjct: 3204 TALFPTRSATSVLVGEPTTSPISSGSTETTALPG-----------------STTTAGLSE 3246
Query: 905 NQSPEATSPRSPGVR-SPVQCVSPELALTIALNPGGRPKEPHLHSYKEAFEEMEGTSPSS 963
+ +SPRSP SP S ++ + RP H ++ + M G S S
Sbjct: 3247 KSTTFYSSPRSPDTTLSPASTTSSGVSEE-STTSHSRPGSTHTTAFPGS-TTMPGVSQES 3304
Query: 964 PPPSGVRSPPGLAKTPLSALGLKPHNPADILLHPTGVTRRRIQPEEDEGKVVVRLSEEPR 1023
+ S PG T LS P T + PE
Sbjct: 3305 ---TASHSSPGSTDTTLS---------------PGSTTASSLGPE--------------- 3331
Query: 1024 SYVESVARTAVAGPRAQDSEPKSFSAPATQAYGHEIPLRNGTLGGSFVSPSPLSTSSPIL 1083
+ T +GP + ++ + A+ P+ + T G + SP +++
Sbjct: 3332 ------STTFHSGPGSTETTLLPDNTTASGLLEASTPVHSST-GSPHTTLSPAGSTTR-- 3382
Query: 1084 SADSTSVGSFPSGESSDQGPRTPTQPLLESGFRSGSLGQPSPSAQRNYQSSSPLPTVG-S 1142
+ST+ S+P+ + + P T T +E + S G PS + ++ +SS T+G S
Sbjct: 3383 QGESTTFQSWPNSKDTTPAPPTTTSAFVE--LSTTSHGSPSSTPTTHFSASS--TTLGRS 3438
Query: 1143 SYSSPDYSLQHFSSSPESQARAQFS-----VAGVHTVPGSPQARHRTVGTNTPPSPGFGW 1197
S+ +S +++ S AR+ S H+ PGS Q H
Sbjct: 3439 EESTTVHSSPVATATTPSPARSTTSGLVEESTTYHSSPGSTQTMH--------------- 3483
Query: 1198 RAINPSMAAPSSPSLSHHQMMGPPGTGFHGSTVSSPQSSAATTPGSPSLCRHPAGVYQVS 1257
P S + S G T H ST + S+ +TT +L P +
Sbjct: 3484 --------FPESDTTSGR---GEESTTSHSSTTHTISSAPSTT---SALVEEPTSYHSSP 3529
Query: 1258 GLHNKVATTPGSPSLGR---HPGAHQGNLASGLHSNAIASPGSPSLGRHLGGSGSVVPGS 1314
G S + GR +H A+G I P + LG S + S
Sbjct: 3530 GSTATTHFPDSSTTSGRSEESTASHSSQDATG----TIVLPARSTTSVLLGESTTSPISS 3585
Query: 1315 PCLDRHVAYGGYSTPEDRRPTLSRQSSASGYQAPSTPSFPVSPA--YYPGLSSPATSP-- 1370
++ G +TP + S + + +P +P+ +SPA G+S +T+
Sbjct: 3586 GSMETTALPGSTTTPG------LSEKSTTFHSSPRSPATTLSPASTTSSGVSEESTTSHS 3639
Query: 1371 ---SPDSAAFRQGSPTPALPEKRRMSVGDRAGS----LPNYATINGKVSSPVASGMSSP- 1422
S + AF + TP L S + LP T +G S SS
Sbjct: 3640 RPGSTHTTAFPDSTTTPGLSRHSTTSHSSPGSTDTTLLPASTTTSGSSQESTTSHSSSGS 3699
Query: 1423 -----SGGSTVSFSHTLPDFSKYSMPDNSPET 1449
S GST + S + +S P ++ T
Sbjct: 3700 TDTALSPGSTTALSFGQESTTFHSSPGSTHTT 3731
Score = 54.3 bits (129), Expect = 1e-06
Identities = 253/1206 (20%), Positives = 408/1206 (33%), Gaps = 212/1206 (17%)
Query: 375 LHGSTGAVNATRPTL-SATPNHVEHTLSVSSDSGNST------ASTKTDKTDEPVP--GA 425
+H S A T P SAT HVE + + G++ +ST + ++E G+
Sbjct: 476 VHSSPVATATTPPPARSATSGHVEESTAYHRSPGSTQTMHFPESSTTSGHSEESATFHGS 535
Query: 426 SSATAALSPQEKRELDRLLSGFGLEREKQGAMYHTQHLRSRPAGGSAVPSSGRHVVPAQV 485
++ T + +P L L G+ T S G + S H P +
Sbjct: 536 TTHTKSSTPSTTAALAHTSYHSSL-----GSTETTHFRDSSTISGRSEESKASHSSPDAM 590
Query: 486 HVNGGALASERETDILDDELPNQDGHSAGSMGTLS-----SLDGVTNTSEGGYPEALSPL 540
A + ++ D P+ S+GSM T + + G++ S Y SP
Sbjct: 591 ATTV-LPAGSTPSVLVGDSTPSPI--SSGSMETTALPGSTTKPGLSEKSTTFYSSPRSPD 647
Query: 541 TNGLDKSYPMEPMVNGGGYPYESASRAGPAHAGHTAPMRPSYS----AQEGLAGYQREGP 596
T L S + G ES + + HT S + +QE A + GP
Sbjct: 648 TTHLPAS------MTSSGVSEESTTSHSRPGSTHTTAFPGSTTMPGLSQESTASHSSPGP 701
Query: 597 HPAWPQPVTTSHYAHDPS-GMFRSQSFSEAEPQLPP-----------APVR--------- 635
P +T+ + P F S+ S LP PV
Sbjct: 702 TDTTLSPGSTTASSLGPEYTTFHSRPGSTETTLLPDNTTASGLLEASMPVHSSTRSPHTT 761
Query: 636 ----GGSSREAVQRGLNSWQQQQQQQQQPRPPPRQQERAHLESLVASRPSPQPLAETPIP 691
G ++R+ +SW + RP P A +E S SP + T I
Sbjct: 762 LSPAGSTTRQGESTTFHSWPSSKDT----RPAPPTTTSAFVEPSTTSHGSPSSIPTTHIS 817
Query: 692 S-------------------------LPEFPRAASQQEIEQSIETLNMLMLDLEPASAAA 726
+ PE + + E + + + P++ +A
Sbjct: 818 ARSTTSGLVEESTTYHSSPGSTQTMHFPESDTTSGRGEESTTSHSSTTHTISSAPSTTSA 877
Query: 727 PLHKSQSVPGAWPGASPLSSQPLSGS-SRQSHPLTQSRSGYIPSGHSL------------ 773
+ + S + PG++ + P S + S +S T S S +G +
Sbjct: 878 LVEEPTSYHSS-PGSTATTHFPDSSTTSGRSEESTASHSSQDATGTIVLPARSTTSVLLG 936
Query: 774 -GTPEPAPRASLESVP-PGRSYSPYDYQPCLAGPNQDFHS--KSPASSSLPAFLP----- 824
T P S+E+ PG + +P L+ + FHS +SPA++ PA
Sbjct: 937 ESTTSPISSGSMETTALPGSTTTPG-----LSERSTTFHSSPRSPATTLSPASTTSSGVS 991
Query: 825 ----TTHSPPGPQQPPASLPGLTAQPLLSPKEATSD-----------PSRTPEEEPLNLE 869
T+ S PG A P T P LS TS P+ T P + E
Sbjct: 992 EESTTSRSRPGSTHTTA-FPDSTTTPGLSRHSTTSHSSPGSTDTTLLPASTTTSGP-SQE 1049
Query: 870 GLVAHRVAGVQAREKQPAEPPAPLRRRAASDGQYENQSPEAT----SPRSPG-VRSPVQC 924
+H +G P A + ++ S T S S G V + +
Sbjct: 1050 STTSHSSSGSTDTALSPGSTTALSFGQESTTFHSNPGSTHTTLFPDSTTSSGIVEASTRV 1109
Query: 925 VSPELALTIALNPGGRPKEPHLHSYKEAFEEMEGTSPSSP-PPSGVRSPPGLAKTPLSAL 983
S + L+P P L AF+ ++ ++P PPS +P + T +
Sbjct: 1110 HSSTGSPRTTLSPASSTS-PGLQGESTAFQTHPASTHTTPSPPSTATAPVEESTTYHRSP 1168
Query: 984 GLKP------------HNPADILLH---------PTGV----------TRRRIQPEEDEG 1012
G P H+ + H P+ T RI P E
Sbjct: 1169 GSTPTTHFPASSTTSGHSEKSTIFHSSPDASGTTPSSAHSTTSGRGESTTSRISPGSTEI 1228
Query: 1013 KVVVRLSEEPRSYVESVARTAVAGPRAQDSEPKSFSAPATQA---YGHEIPLRNGTLGGS 1069
+ + P + + T + PR+ P + +PA+ G E G +
Sbjct: 1229 TTLPGSTTTPG--LSEASTTFYSSPRS----PTTTLSPASMTSLGVGEESTTSRSQPGST 1282
Query: 1070 FVSPSPLSTSSPILSADSTSVGSFPSGESSDQGPRTPTQPLLESGFRSGSLGQPSPSAQR 1129
+ SP ST++P LS +ST+V S G T T S S +P+ R
Sbjct: 1283 HSTVSPASTTTPGLSEESTTVYSSSRGS-------TETTVFPHSTTTSVHGEEPTTFHSR 1335
Query: 1130 NYQSSSPLPTVGSSYSSPDYSLQHFSSSPESQAR---AQFSVAGVHTVPGSPQARHRTVG 1186
+ + L T S+ S F SP S A + A + + + + G
Sbjct: 1336 PASTHTTLFTEDSTTSGLTEESTAFPGSPASTQTGLPATLTTADLGEESTTFPSSSGSTG 1395
Query: 1187 TNTPPSPGFGWRAINPSMAAPSSPSLSHHQMM-GPPGTGFHGSTVSSPQSSAATTPGSPS 1245
T P+ + S + SPS + + G P T ++S ++ T+P SP
Sbjct: 1396 TKLSPARSTTSGLVGESTPSRLSPSSTETTTLPGSPTT----PSLSEKSTTFYTSPRSPD 1451
Query: 1246 LCRHPAGVYQVSGLHNKVATT---PGSPSLGRHPGAHQGNLASGLHSNAIASPGSPSLGR 1302
PA SG+ + +T+ PGS P + + S + + +S GS
Sbjct: 1452 ATLSPATTTS-SGVSEESSTSHSQPGSTHTTAFPDSTTTSDLSQEPTTSHSSQGSTEATL 1510
Query: 1303 HLGGSGSVVPGSPCLDRHVAYGGYSTPEDRRPTLSRQSS-ASGYQAPSTPSFPVSPAYYP 1361
G + + G H S+P D TL + SG STP+ + +
Sbjct: 1511 SPGSTTASSLGQQSTTFH------SSPGDTETTLLPDDTITSGLVEASTPTHSSTGS--- 1561
Query: 1362 GLSSPATSPSPDSAAFRQGSPT----PALPEKRRMSVGDRAGSLPNYATINGKVSSPVAS 1417
L + T S SA ++ S T P+ + G A + T + + SS +
Sbjct: 1562 -LHTTLTPASSTSAGLQEESTTFQSWPSSSDTTPSPPGTTAAPVEVSTTYHSRPSSTPTT 1620
Query: 1418 GMSSPS 1423
S+ S
Sbjct: 1621 HFSASS 1626
Score = 54.3 bits (129), Expect = 1e-06
Identities = 238/1132 (21%), Positives = 378/1132 (33%), Gaps = 184/1132 (16%)
Query: 370 KKKDSLHGSTGAVN-ATRPTLSATPNHVEHTLSVSSDSGNSTASTKTDKTDEPVPGASSA 428
++ ++H S GA A PT SAT V + SG++ + T S
Sbjct: 3190 EESTTVHSSPGATGTALFPTRSATSVLVGEPTTSPISSGSTETTALPGSTTTAGLSEKST 3249
Query: 429 TAALSPQEKRELDRLLSGFGLEREKQGAMYHTQHLRSRPAGGSAVPSSGRHVVPAQVHVN 488
T SP R D LS T H SRP G +P V+
Sbjct: 3250 TFYSSP---RSPDTTLSPASTTSSGVSEESTTSH--SRPGSTHTTAFPGSTTMPG---VS 3301
Query: 489 GGALASERETDILDDELPNQDGHSAGSMG----TLSSLDGVT-------NTSEGGYPEAL 537
+ AS D L + +A S+G T S G T NT+ G EA
Sbjct: 3302 QESTASHSSPGSTDTTL-SPGSTTASSLGPESTTFHSGPGSTETTLLPDNTTASGLLEAS 3360
Query: 538 SPLTNGLDKSYPMEPMVNGGGYPYESASRAGPAHAGHTAPMRPSYSAQEGLAGYQREGPH 597
+P+ + + ES + ++ T P P+ ++ A +
Sbjct: 3361 TPVHSSTGSPHTTLSPAGSTTRQGESTTFQSWPNSKDTTPAPPTTTS----AFVELSTTS 3416
Query: 598 PAWPQPVTTSHYAHDPSGMFRSQSFSEAEPQLPPAPVRGGSSREAVQRGLNSWQQQQQQQ 657
P T+H++ + + RS E + +PV ++
Sbjct: 3417 HGSPSSTPTTHFSASSTTLGRS----EESTTVHSSPVATATTPS---------------- 3456
Query: 658 QQPRPPPRQQERAHLESLVASRPSPQPLAETPIPSLPEFPRAASQQEIEQSIETLNMLML 717
P R +E SP T PE + + E + + +
Sbjct: 3457 -----PARSTTSGLVEESTTYHSSP---GSTQTMHFPESDTTSGRGEESTTSHSSTTHTI 3508
Query: 718 DLEPASAAAPLHKSQSVPGAWPGASPLSSQPLSGS-SRQSHPLTQSRSGYIPSGHSL--- 773
P++ +A + + S + PG++ + P S + S +S T S S +G +
Sbjct: 3509 SSAPSTTSALVEEPTSYHSS-PGSTATTHFPDSSTTSGRSEESTASHSSQDATGTIVLPA 3567
Query: 774 ----------GTPEPAPRASLESVP-PGRSYSPYDYQPCLAGPNQDFHS--KSPASSSLP 820
T P S+E+ PG + +P L+ + FHS +SPA++ P
Sbjct: 3568 RSTTSVLLGESTTSPISSGSMETTALPGSTTTPG-----LSEKSTTFHSSPRSPATTLSP 3622
Query: 821 AFLP---------TTHSPPGPQQPPASLPGLTAQPLLSPKEATSDPSRTPEEEPL----- 866
A T+HS PG A P T P LS TS S + L
Sbjct: 3623 ASTTSSGVSEESTTSHSRPGSTHTTA-FPDSTTTPGLSRHSTTSHSSPGSTDTTLLPAST 3681
Query: 867 -----NLEGLVAHRVAGVQAREKQPAEPPAPLRRRAASDGQYE---NQSPEAT------- 911
+ E +H +G P A S GQ + SP +T
Sbjct: 3682 TTSGSSQESTTSHSSSGSTDTALSPGSTTA------LSFGQESTTFHSSPGSTHTTLFPD 3735
Query: 912 SPRSPG-VRSPVQCVSPELALTIALNPGGRPKEPHLHSYKEAFEEMEGTSPSSP-PPSGV 969
S S G V + + S + L+P P L AF+ ++ ++P PPS
Sbjct: 3736 STTSSGIVEASTRVHSSTGSPRTTLSPASSTS-PGLQGESTAFQTHPASTHTTPSPPSTA 3794
Query: 970 RSPPGLAKTPLSALGLKP------------HNPADILLH---------PTGV-------- 1000
+P + T + G P H+ + H P+
Sbjct: 3795 TAPVEESTTYHRSPGSTPTTHFPASSTTSGHSEKSTIFHSSPDASGTTPSSAHSTTSGRG 3854
Query: 1001 --TRRRIQPEEDEGKVVVRLSEEPRSYVESVARTAVAGPRAQDSEPKSFSAPATQA---Y 1055
T RI P E + + P + + T + PR+ P + +PA+
Sbjct: 3855 ESTTSRISPGSTEITTLPGSTTTPG--LSEASTTFYSSPRS----PTTTLSPASMTSLGV 3908
Query: 1056 GHEIPLRNGTLGGSFVSPSPLSTSSPILSADSTSV-GSFPSGESSDQGPRTPTQPLLESG 1114
G E G + + SP ST++P LS +ST+V S P + PR+ T +
Sbjct: 3909 GEESTTSRSQPGSTHSTVSPASTTTPGLSEESTTVYSSSPGSTETTVFPRSTTTSVRRE- 3967
Query: 1115 FRSGSLGQPSPSAQRNYQSSSPLPTVGSSYSSPDYSLQHFSSSPESQAR---AQFSVAGV 1171
+P+ R + + L T S+ S F SP S A + A +
Sbjct: 3968 -------EPTTFHSRPASTHTTLFTEDSTTSGLTEESTAFPGSPASTQTGLPATLTTADL 4020
Query: 1172 HTVPGSPQARHRTVGTNTPPSPGFGWRAINPSMAAPSSPSLSHHQMM-GPPGTGFHGSTV 1230
+ + + GT P+ + S + SPS + + G P T ++
Sbjct: 4021 GEESTTFPSSSGSTGTKLSPARSTTSGLVGESTPSRLSPSSTETTTLPGSPTT----PSL 4076
Query: 1231 SSPQSSAATTPGSPSLCRHPAGVYQVSGLHNKVATTPGSPSLGRHPGAHQGNLASGLHSN 1290
S ++ T+P SP PA SG+ + +T+ P SGL
Sbjct: 4077 SEKSTTFYTSPRSPDATLSPATTTS-SGVSEESSTSHSQPGSTHTTAFPDSTTTSGLSQE 4135
Query: 1291 AIASPGSPSLGRHLGGSGSVVPGSPCLDRHVAYGGYSTPEDRRPTLSRQSS-ASGYQAPS 1349
S S GS S + +S+P D TL + SG S
Sbjct: 4136 PTTSHSSQGSTEATLSPGSTTASSL---GQQSTTFHSSPGDTETTLLPDDTITSGLVEAS 4192
Query: 1350 TPSFPVSPAYYPGL---SSPATSPSPDSAAFR----QGSPTPALPEKRRMSV 1394
TP+ + + + L SS +T +S F+ TP+ P + V
Sbjct: 4193 TPTHSSTGSLHTTLTPASSTSTGLQEESTTFQSWPSSSDTTPSPPSTTAVPV 4244
Score = 52.4 bits (124), Expect = 4e-06
Identities = 109/464 (23%), Positives = 171/464 (36%), Gaps = 46/464 (9%)
Query: 1028 SVARTAVAG----PRAQDSEPKSFSAPATQAYGHEIPLRNGTLGGS----FVSPSPLSTS 1079
S+ TA+ G P + S+P++ H + TLG S V SP++T+
Sbjct: 4670 SMETTALPGSTTTPGLSEKSTTFHSSPSSTPTTH-FSASSTTLGRSEESTTVHSSPVATA 4728
Query: 1080 SPILSADSTSVGSFPSGESSDQGP-RTPTQPLLESGFRSGSLGQPSPS-AQRNYQSSSPL 1137
+ A ST+ G + P T T ES SG + S + + SSP
Sbjct: 4729 TTPSPARSTTSGLVEESTAYHSSPGSTQTMHFPESSTASGRSEESRTSHSSTTHTISSPP 4788
Query: 1138 PTVG-------SSYSSP-DYSLQHFSSSPESQARAQFSVAGVHTVPGS----PQARHRTV 1185
T S +SSP + HF S + R++ S A H+ P + P H T
Sbjct: 4789 STTSALVEEPTSYHSSPGSIATTHFPESSTTSGRSEESTAS-HSSPDTNGITPLPAHFTT 4847
Query: 1186 GTNTPPSPGFGWRAINPSMAAPSSPSLSHHQMMGPPGTGFHGSTVSSPQSSAATTPGSPS 1245
S F I+P + S + + T + S+ S Q+ + + S S
Sbjct: 4848 SGRIAESTTF---YISPGSMETTLASTATTPGLSAKSTILYSSSRSPDQTLSPASMTSSS 4904
Query: 1246 LCRHPAGVY-QVSGLHNKV----ATTPG----SPSLGRHPGAHQGNLASG-LHSNAIASP 1295
+ P +Y Q H TT G S + PG+ + L+ G + +++ A
Sbjct: 4905 ISGEPTSLYSQAESTHTTAFPASTTTSGLSQESTTFHSKPGSTETTLSPGSITTSSFAQE 4964
Query: 1296 GSPSLGRHLGGSGSVVPGSPCLD--RHVAYGGYSTPEDRRPTLSRQSSASGYQAPSTPSF 1353
+ + +V P S + + YS+P T S+ + + F
Sbjct: 4965 FTTPHSQPGSALSTVSPASTTVPGLSEESTTFYSSPGSTETTAFSHSNTMSIHSQQSTPF 5024
Query: 1354 PVSPAYYPGLSSPATSPSPD----SAAFRQGS-PTPALPEKRRMSVGDRAGSLPNYATIN 1408
P SP + + PAT + D S AF S T P R + D G +
Sbjct: 5025 PDSPGFTHTV-LPATLTTTDIGQESTAFHSSSDATGTTPLPARSTASDLVGEPTTFYISP 5083
Query: 1409 GKVSSPVASGMSSPSGGSTVSFS-HTLPDFSKYSMPDNSPETRA 1451
+ + SS SG + S + HT P F+ + S ET A
Sbjct: 5084 SPTYTTLFPASSSTSGLTEESTTFHTSPSFTSTIVSTESLETLA 5127
Score = 50.8 bits (120), Expect = 1e-05
Identities = 240/1145 (20%), Positives = 371/1145 (32%), Gaps = 139/1145 (12%)
Query: 376 HGSTGAVNATR-PTLSATPNHVEHTLSVSSDSGNSTASTKTDKTDEPVPGASSATAALSP 434
H G+ + T P + TP H+ + S G++ + T P S T+ SP
Sbjct: 2081 HSRPGSTHTTAFPDSTTTPGLSRHSTTSHSSPGSTDTTLLPASTTTSGPSQESTTSHSSP 2140
Query: 435 QEKRELDRLLSGFGLEREKQGAMYHTQ----HLRSRPAGGSAVPSSGRHVVPAQVHVNGG 490
S L ++ +H+ H P + SSG +VH + G
Sbjct: 2141 GSTDTALSPGSTTALSFGQESTTFHSSPGSTHTTLFP---DSTTSSGIVEASTRVHSSTG 2197
Query: 491 A----LASERETDI-LDDELPNQDGHSAGSMGTLSSLDGVTNTSEGGYPEALSPLTNGLD 545
+ L+ T L E H A + T S T E SP +
Sbjct: 2198 SPRTTLSPASSTSPGLQGESTAFQTHPASTHTTPSPPSTATAPVEESTTYHRSPGSTPTT 2257
Query: 546 KSYPMEPMVNGGGYPYESASRAGPAHAGHTAPMRPSYSAQEGLAGYQREGPHPAWPQPVT 605
+P +G + + P +G T S ++ G + R P +T
Sbjct: 2258 H-FPASSTTSGHSEK-STIFHSSPDASGTTPSSAHSTTSGRGESTTSRISPGST---EIT 2312
Query: 606 TSHYAHDPSGMFRSQSFSEAEPQLPPAPVRGGS--SREAVQRGLNSWQQQQQQQQQPRPP 663
T + G+ + + + P+ P + S S + S Q P
Sbjct: 2313 TLPGSTTTPGLSEASTTFYSSPRSPTTTLSPASMTSLGVGEESTTSRSQPGSTHSTVSPA 2372
Query: 664 PRQQERAHLESLVASRPSPQPLAETPIPSLPEFPRAASQQEIEQSIETLNMLMLDLEPAS 723
ES SP T P P + S L E ++
Sbjct: 2373 STTTPGLSEESTTVYSSSPGSTETTVFPRTPTTSVRGEEPTTFHSRPASTHTTLFTEDST 2432
Query: 724 AAAPLHKSQSVPGAWPGASPLSSQPLSGSSRQSHPLTQSRSGYIPSGHSLGTPEPAPRAS 783
+ +S + PG SP S+Q ++ + L + + + S S GT R++
Sbjct: 2433 TSGLTEESTAFPG-----SPASTQTGLPATLTTADLGEESTTFPSSSGSTGTTLSPARST 2487
Query: 784 L-----ESVPPGRSYSPYDYQ--------PCLAGPNQDFHSK--------SPA---SSSL 819
ES P S S + P L+ + F++ SPA SS +
Sbjct: 2488 TSGLVGESTPSRLSPSSTETTTLPGSPTTPSLSEKSTTFYTSPRSPDATLSPATTTSSGV 2547
Query: 820 PAFLPTTHSPPGPQQPPA------------------SLPGLTAQPLLSPKEATSDPSR-- 859
T+HS PG A S PG T LL TS PS+
Sbjct: 2548 SEESSTSHSQPGSTHTTAFPDSTTTPGLSRHSTTSHSSPGSTDTTLLPASTTTSGPSQES 2607
Query: 860 -TPEEEPLNLE-GLVAHRVAGVQAREKQPAEPPAP-------LRRRAASDGQYENQSPEA 910
T P + + L + ++ +P S G E +
Sbjct: 2608 TTSHSSPGSTDTALSPGSTTALSFGQESTTFHSSPGSTHTTLFPDSTTSSGIVEASTRVH 2667
Query: 911 TSPRSPGVR-SPVQCVSPEL---ALTIALNPGGRPKEPHLHSYKEAFEEMEGT---SPSS 963
+S SP SP SP L + T +P P S A E T SP S
Sbjct: 2668 SSTGSPRTTLSPASSTSPGLQGESTTFQTHPASTHTTPSPPSTATAPVEESTTYHRSPGS 2727
Query: 964 PPP---------SGVRSPPGLAKTPLSALGLKPHNPADILLHPTGVTRRRIQPEEDEGKV 1014
P SG + + A G P + T RI P E
Sbjct: 2728 TPTTHFPASSTTSGHSEKSTIFHSSPDASGTTPSSAHSTTSGRGESTTSRISPGSTEITT 2787
Query: 1015 VVRLSEEPRSYVESVARTAVAGPRAQDSEPKSFSAPATQA---YGHEIPLRNGTLGGSFV 1071
+ + P + + T + PR+ P + +PA+ G E G +
Sbjct: 2788 LPGSTTTPG--LSEASTTFYSSPRS----PTTTLSPASMTSLGVGEESTTSRSQPGSTHS 2841
Query: 1072 SPSPLSTSSPILSADSTSV-GSFPSGESSDQGPRTPTQPLLESGFRSGSLGQPSPSAQRN 1130
+ SP ST++P LS +ST+V S P + PR+ T + +P+ R
Sbjct: 2842 TVSPASTTTPGLSEESTTVYSSSPGSTETTVFPRSTTTSVRGE--------EPTTFHSRP 2893
Query: 1131 YQSSSPLPTVGSSYSSPDYSLQHFSSSPESQAR---AQFSVAGV----HTVPGSPQARHR 1183
+ + L T S+ S F SP S A + A + T P S +
Sbjct: 2894 ASTHTTLFTEDSTTSGLTEESTAFPGSPASTQTGLPATLTTADLGEESTTFPSSSGSTGT 2953
Query: 1184 TVGTNTPPSPGFGWRAINPSMAAPSSPSLSHHQMMGPPGTGFHGSTVSSPQSSAATTPGS 1243
T+ + G + PS +PSS + + G P T ++S ++ T+P S
Sbjct: 2954 TLSPARSTTSGLVGES-TPSRLSPSSTETT--TLPGSPTT----PSLSEKSTTFYTSPRS 3006
Query: 1244 PSLCRHPAGVYQVSGLHNKVATTPGSPSLGRHPGAHQGNLASGLHSNAIASPGSPSLGRH 1303
P PA SG+ + +T+ P SGL AS S
Sbjct: 3007 PDATLSPATTTS-SGVSEESSTSHSQPGSTHTTAFPDSTTTSGLSQEPTASHSSQGSTEA 3065
Query: 1304 LGGSGSVVPGSPCLDRHVAYGGYSTPEDRRPTLSRQSS-ASGYQAPSTPSFPVSPAYYPG 1362
GS S + +S+P D TL + SG STP+ + +
Sbjct: 3066 TLSPGSTTASSL---GQQSTTFHSSPGDTETTLLPDDTITSGLVEASTPTHSSTGS---- 3118
Query: 1363 LSSPATSPSPDSAAFRQGSPT----PALPEKRRMSVGDRAGSLPNYATINGKVSSPVASG 1418
L + T S SA ++ S T P+ + G A + T + + SS +
Sbjct: 3119 LHTTLTPASSTSAGLQEESTTFQSWPSSSDTTPSPPGTTAAPVEVSTTYHSRPSSTPTTH 3178
Query: 1419 MSSPS 1423
S+ S
Sbjct: 3179 FSASS 3183
Score = 48.1 bits (113), Expect = 7e-05
Identities = 202/999 (20%), Positives = 319/999 (31%), Gaps = 171/999 (17%)
Query: 369 VKKKDSLHGSTGAVNATRPTLSATPNHVEHTLSVSSDSGNSTASTKTDKTDEPVPGASSA 428
V+ H STG+++ T S+T ++ + +S+ +T + + VP S
Sbjct: 4189 VEASTPTHSSTGSLHTTLTPASSTSTGLQEESTTFQSWPSSSDTTPSPPSTTAVPVEVST 4248
Query: 429 TAALSPQEKRELDRLLSGFGLEREKQGAMYHTQHLRSRPAGGSAVPSSGRHVVPAQVHVN 488
T P S L R ++ H+ S A G+A+
Sbjct: 4249 TYHSRPSSTPTTHFSASSTTLGRSEESTTVHS----SPGATGTAL--------------- 4289
Query: 489 GGALASERETDILDDELPNQDGHSAGSMGTLSSLDGVTNTSEGGYPEALSPLTNGLDKSY 548
+ T +L E P S+GS T ++L G T T+ G ++ + ++
Sbjct: 4290 ---FPTRSATSVLVGE-PTTSPISSGSTET-TALPGSTTTA-GLSEKSTTFYSSPRSPDT 4343
Query: 549 PMEP-MVNGGGYPYESASRAGPAHAGHTAPMRPSYS----AQEGLAGYQREGPHPAWPQP 603
+ P G ES + + HT S + +QE A + G P
Sbjct: 4344 TLSPASTTSSGVSEESTTSHSRPGSMHTTAFPSSTTMPGVSQESTASHSSPGSTDTTLSP 4403
Query: 604 VTTSHYAHDP-SGMFRSQSFSEAEPQLP-----------PAPVR-------------GGS 638
+T+ + P S F S S LP PV G +
Sbjct: 4404 GSTTASSLGPESTTFHSSPGSTETTLLPDNTTASGLLEASTPVHSSTGSPHTTLSPAGST 4463
Query: 639 SREAVQRGLNSWQQQQQQQQQPRPPPRQQERAHLESLVASRPSPQPLAETPIPSLPEFPR 698
+R+ SW + P P A +E S SP S P
Sbjct: 4464 TRQGESTTFQSW----PNSKDTTPAPPTTTSAFVELSTTSHGSPS--------STPTTHF 4511
Query: 699 AASQQEIEQSIETLNMLMLDLEPASAAAPLHKS-----------QSVPGAWPGASPLSSQ 747
+AS + +S E+ + + A+ +P + S PG+ S
Sbjct: 4512 SASSTTLGRSEESTTVHSSPVATATTPSPARSTTSGLVEESTTYHSSPGSTQTMHFPESN 4571
Query: 748 PLSG---SSRQSHPLTQSRSGYIPSGHSLGTPEPAPRASLESVPPGRSYSPYDYQPCLAG 804
SG S SH T PS S EP S S P + + + +G
Sbjct: 4572 TTSGRGEESTTSHSSTTHTISSAPSTTSALVEEP---TSYHSSPGSTATTHFPDSSTTSG 4628
Query: 805 PNQD---FHSKSPASSS--LPAFLPT-------THSP-PGPQQPPASLPGLTAQPLLSPK 851
+++ HS A+ + LPA T T SP +LPG T P LS K
Sbjct: 4629 RSEESTASHSSQDATGTIVLPARSTTSVLLGESTTSPISSGSMETTALPGSTTTPGLSEK 4688
Query: 852 EAT--SDPSRTPEEEPLNLEGLVAHRVAGVQAREKQPAEPPAPLRRRAASDGQYENQSPE 909
T S PS TP + A P R+ + G E +
Sbjct: 4689 STTFHSSPSSTPTTHFSASSTTLGRSEESTTVHSSPVATATTPSPARSTTSGLVEESTAY 4748
Query: 910 ATSPRSPGVRSPVQCVSPELALTIALNPGGRPKE---PHLHSYKEAFEEMEGTSPSSPPP 966
+SP S + + + GR +E H + TS P
Sbjct: 4749 HSSPGS----------TQTMHFPESSTASGRSEESRTSHSSTTHTISSPPSTTSALVEEP 4798
Query: 967 SGVRSPPG-LAKTPLSALGLKPHNPADILLHPTGVTRRRIQPEEDEGKVVVRLSEEPRSY 1025
+ S PG +A T + + I P R++E Y
Sbjct: 4799 TSYHSSPGSIATTHFPESSTTSGRSEESTASHSSPDTNGITPLPAHFTTSGRIAESTTFY 4858
Query: 1026 VE------SVARTAV------------AGPRAQDSEPKSFSAPATQAYGHEIPLRNGTLG 1067
+ ++A TA + R+ D S ++ G L +
Sbjct: 4859 ISPGSMETTLASTATTPGLSAKSTILYSSSRSPDQTLSPASMTSSSISGEPTSLYS-QAE 4917
Query: 1068 GSFVSPSPLSTSSPILSADSTSVGSFPSGESSDQGPRTPTQPLLESGFRSGSLGQPSPSA 1127
+ + P ST++ LS +ST+ S P + P + T F + QP +
Sbjct: 4918 STHTTAFPASTTTSGLSQESTTFHSKPGSTETTLSPGSITTSSFAQEFTTPH-SQPGSAL 4976
Query: 1128 QRNYQSSSPLPTVGSSYSSPDYSLQHFSSSPESQARAQFSVAGVHTVPGSPQARHRTVGT 1187
+S+ +P + ++ F SSP S FS + ++ H T
Sbjct: 4977 STVSPASTTVPGLSEESTT-------FYSSPGSTETTAFSHSNTMSI-------HSQQST 5022
Query: 1188 NTPPSPGFGWRAINPSMAAPSSPSLSHHQMMGPPGTGFH------GSTVSSPQSSAATTP 1241
P SPGF + ++ +G T FH G+T +S+A+
Sbjct: 5023 PFPDSPGFTHTVLPATLTTTD---------IGQESTAFHSSSDATGTTPLPARSTASDLV 5073
Query: 1242 GSP-SLCRHPAGVY--------QVSGLHNKVATTPGSPS 1271
G P + P+ Y SGL + T SPS
Sbjct: 5074 GEPTTFYISPSPTYTTLFPASSSTSGLTEESTTFHTSPS 5112
Score = 44.7 bits (104), Expect = 8e-04
Identities = 223/1141 (19%), Positives = 360/1141 (31%), Gaps = 212/1141 (18%)
Query: 378 STGAVNATRPTLSATPNHVEHTLSVSSDSG------NSTASTKTDKTDEPVPGASSATAA 431
+T ++ T ++P TLS +S + ++T+ ++ T V AS+ T
Sbjct: 3876 TTPGLSEASTTFYSSPRSPTTTLSPASMTSLGVGEESTTSRSQPGSTHSTVSPASTTTPG 3935
Query: 432 LSPQEKRELDRLLSGFGLEREKQGAMYHTQHLRSRPAGGSAVPSSGRHVVPAQVHVNGGA 491
LS + + G+ T RS + H PA H
Sbjct: 3936 LSEESTT----------VYSSSPGSTETTVFPRSTTTSVRREEPTTFHSRPASTHTT--L 3983
Query: 492 LASERETDILDDELPNQDGHSAGSMGTLSSLDGVTNTSEGGYPEALSPLTNGLDKSYPME 551
+ T L +E G A T + L T++ G P ++G +
Sbjct: 3984 FTEDSTTSGLTEESTAFPGSPAS---TQTGLPATLTTADLGEESTTFPSSSGSTGTKLSP 4040
Query: 552 PMVNGGGYPYESA-SRAGPAHAGHT----APMRPSYSAQEGLAGYQREGPHPAWPQPVTT 606
G ES SR P+ T +P PS S + P TT
Sbjct: 4041 ARSTTSGLVGESTPSRLSPSSTETTTLPGSPTTPSLSEKSTTFYTSPRSPDATLSPATTT 4100
Query: 607 SHYAHDPSGMFRSQSFSEAEPQLPPAPVRGGSSREAVQRGLNSWQQQQQQQQQPRPPPRQ 666
S + S SQ S P + G S+E Q + P
Sbjct: 4101 SSGVSEESSTSHSQPGSTHTTAFPDSTTTSGLSQEPTTS-----HSSQGSTEATLSPGST 4155
Query: 667 QERAHLESLVASRPSPQPLAETPIPSLPEFPRAASQQEIEQSIET---LNMLMLDLEPAS 723
+ + SP T +P + +E S T L L PAS
Sbjct: 4156 TASSLGQQSTTFHSSPGDTETTLLPD-----DTITSGLVEASTPTHSSTGSLHTTLTPAS 4210
Query: 724 AAAP-LHKSQSVPGAWPGASPLSSQPLSGSSRQSHPLTQSRSGYIPSGHSLGTPEPAPRA 782
+ + L + + +WP +S + P S ++ T + HS + P
Sbjct: 4211 STSTGLQEESTTFQSWPSSSDTTPSPPSTTAVPVEVST--------TYHSRPSSTPTTHF 4262
Query: 783 SLESVPPGRSYSPYDYQPCLAGPNQDFHSKSPASSSLPAFLPTTHSPPGPQQPPASLPGL 842
S S GRS T HS PG
Sbjct: 4263 SASSTTLGRSEES----------------------------TTVHSSPGA---------- 4284
Query: 843 TAQPLLSPKEATSDPSRTPEEEPLNLEGLVAHRVAGVQAREKQPAEPPAPLRRRAASDGQ 902
T L + ATS P P++ + G + G
Sbjct: 4285 TGTALFPTRSATSVLVGEPTTSPISSGSTETTALPG-----------------STTTAGL 4327
Query: 903 YENQSPEATSPRSPGVR-SPVQCVSPELALTIALNPGGRPKEPHLHSYKEAFEEMEGTSP 961
E + +SPRSP SP S ++ + RP H ++ + M G S
Sbjct: 4328 SEKSTTFYSSPRSPDTTLSPASTTSSGVSEE-STTSHSRPGSMHTTAFPSS-TTMPGVSQ 4385
Query: 962 SSPPPSGVRSPPGLAKTPLSALGLKPHNPADILLHPTGVTRRRIQPEEDEGKVVVRLSEE 1021
S + S PG T LS P T + PE
Sbjct: 4386 ES---TASHSSPGSTDTTLS---------------PGSTTASSLGPE------------- 4414
Query: 1022 PRSYVESVARTAVAGPRAQDSEPKSFSAPATQAYGHEIPLRNGTLGGSFVSPSPLSTSSP 1081
+ T + P + ++ + A+ P+ + T G + SP +++
Sbjct: 4415 --------STTFHSSPGSTETTLLPDNTTASGLLEASTPVHSST-GSPHTTLSPAGSTTR 4465
Query: 1082 ILSADSTSVGSFPSGESSDQGPRTPTQPLLESGFRSGSLGQPSPSAQRNYQS-------- 1133
+ST+ S+P+ + + P T T +E + S G PS + ++ +
Sbjct: 4466 --QGESTTFQSWPNSKDTTPAPPTTTSAFVE--LSTTSHGSPSSTPTTHFSASSTTLGRS 4521
Query: 1134 -------SSPLPTV----------------GSSYSSPDYSLQ--HFSSSPESQARAQFSV 1168
SSP+ T ++Y S S Q HF S + R + S
Sbjct: 4522 EESTTVHSSPVATATTPSPARSTTSGLVEESTTYHSSPGSTQTMHFPESNTTSGRGEEST 4581
Query: 1169 AG----VHTVPGSPQARHRTV--GTNTPPSPGFGWRAINP---SMAAPSSPSLSHHQMMG 1219
HT+ +P V T+ SPG P + + S S + H
Sbjct: 4582 TSHSSTTHTISSAPSTTSALVEEPTSYHSSPGSTATTHFPDSSTTSGRSEESTASHSSQD 4641
Query: 1220 PPGT----------GFHGSTVSSPQSSAA-TTPGSPSLCRHPAGVYQVSGLHNKVATTPG 1268
GT G + +SP SS + T P P + + H+ ++TP
Sbjct: 4642 ATGTIVLPARSTTSVLLGESTTSPISSGSMETTALPGSTTTPGLSEKSTTFHSSPSSTPT 4701
Query: 1269 SPSLGRHPGAHQGNLASGLHSNAIASPGSPSLGRH----LGGSGSVVPGSPCLDRHVAYG 1324
+ + ++ +HS+ +A+ +PS R L + SP + + +
Sbjct: 4702 THFSASSTTLGRSEESTTVHSSPVATATTPSPARSTTSGLVEESTAYHSSPGSTQTMHFP 4761
Query: 1325 GYSTPEDRRPTLSRQSSASGYQAPSTPSFPVSPAYYPGLSSPATSPSPDSAAFRQGSPTP 1384
ST R SR S +S S+P S S ++ S + F + S T
Sbjct: 4762 ESSTASGRSEE-SRTSHSSTTHTISSPPSTTSALVEEPTSYHSSPGSIATTHFPESSTTS 4820
Query: 1385 ALPEKRRMSVG--DRAG--SLPNYATINGKVSSPVASGMSSPSGGSTVSFSHTLPDFSKY 1440
E+ S D G LP + T +G+++ +S S +T++ + T P S
Sbjct: 4821 GRSEESTASHSSPDTNGITPLPAHFTTSGRIAESTTFYISPGSMETTLASTATTPGLSAK 4880
Query: 1441 S 1441
S
Sbjct: 4881 S 4881
>gi|55750053 atrophin-1 [Homo sapiens]
Length = 1190
Score = 70.9 bits (172), Expect = 1e-11
Identities = 164/740 (22%), Positives = 246/740 (33%), Gaps = 154/740 (20%)
Query: 735 PGAWPGASPLSSQPLSGSSRQSHPLTQSRSGYIPSGHSLGTPEPAPRASLESVPPGRSYS 794
PG+ S SS G +R HP + PS P+ PR S P S +
Sbjct: 138 PGSVENDSDSSSGLSQGPARPYHPPPL----FPPSPQP---PDSTPRQPEASFEPHPSVT 190
Query: 795 PYDYQPCLAGPNQDFHSKSPASSSLPAFLPTTHSPPGPQQPPASLPGLTAQPLLSPKEAT 854
P Y + P P + PP PQ P G+ + P + PK
Sbjct: 191 PTGYHAPMEPPTSRMFQAPPGAP-----------PPHPQLYPGGTGGVLSGPPMGPK--- 236
Query: 855 SDPSRTPEEEPLNLEGLVAHRVAGVQAREKQPAEPPAPLRRRAASDGQYENQSPEATSPR 914
G A V G ++ P P P+ +S G + +P P
Sbjct: 237 --------------GGGAASSVGGPNGGKQHP-PPTTPI--SVSSSG--ASGAPPTKPPT 277
Query: 915 SPGVRSPVQCVSPELALTIALNPGGRPKEPHLHSYKEAFEEMEGTSPSSPPPSGVR---- 970
+P + G P P ++ +P+ PPP +R
Sbjct: 278 TP------------------VGGGNLPSAPPPANFPH-------VTPNLPPPPALRPLNN 312
Query: 971 ---SPPGLAKTPLSALGLKPHNPADILLHPTGVTRRRIQPEEDEGKVVVRLSEEPRSYVE 1027
SPPGL PL H P+ H G + P ++G L+ P S
Sbjct: 313 ASASPPGLGAQPLPG-----HLPSP---HAMGQGMGGLPPGPEKGPT---LAPSPHSLPP 361
Query: 1028 SVARTAVAGPRAQDSEPKSFSAPATQAYGHEIPLRNGTLGGSFVSPSPLSTSSPILSADS 1087
+ + R S S SA A+ + + S SP P S + P
Sbjct: 362 ASSSAPAPPMRFPYSSSSSSSAAASS---------SSSSSSSSASPFPASQALP------ 406
Query: 1088 TSVGSFPSGES---SDQGPRTPTQPLLESGFRSGSLGQPSPSAQRNYQSSS-------PL 1137
+ SFP S S+Q P+ TQP L S S G P P ++S P
Sbjct: 407 SYPHSFPPPTSLSVSNQPPKY-TQPSLPSQ-AVWSQGPPPPPPYGRLLANSNAHPGPFPP 464
Query: 1138 PTVGSSYSSPDYSLQHFSSSPESQARAQFSVAGVHTVPGSPQARHRTVGTNTPPSPGFGW 1197
T S + P S H + Q + Q Q + + G + PP PG
Sbjct: 465 STGAQSTAHPPVSTHHHHHQQQQQQQQQ--------QQQQQQQQQQHHGNSGPPPPGAFP 516
Query: 1198 R-------------AINPSMAA--PSSPSLSH----HQMMGPPGTGFHGSTVSSPQSSAA 1238
A++PS+ + P P +H H + G +G VSS +S++
Sbjct: 517 HPLEGGSSHHAHPYAMSPSLGSLRPYPPGPAHLPPPHSQVSYSQAGPNGPPVSSSSNSSS 576
Query: 1239 TTPGSPSLCRHPAGVYQVSGLHNKVATTPGSPSLGRHPGAHQGNLASGLHSNAIAS-PGS 1297
+T C HP+ G P + +AS AS PG
Sbjct: 577 STSQGSYPCSHPSPSQGPQGAPYPFPPVPTVTTSSATLSTVIATVASSPAGYKTASPPGP 636
Query: 1298 PSLGRHLGGSGS--------VVPGSPCLDRHVAYGGY-STPEDRRPTLSRQSSASGYQAP 1348
P G+ G+ PGSP R GY T P + S + P
Sbjct: 637 PPYGKRAPSPGAYKTATPPGYKPGSPPSFRTGTPPGYRGTSPPAGPGTFKPGSPTVGPGP 696
Query: 1349 STPSFPVS-PAYYPGLSSPATSPSPDSAAFRQ------GSPTPALPEKRRMSVGDRAGSL 1401
P+ P P+ P ++PA+ P + +Q +P +P R S + +
Sbjct: 697 LPPAGPSGLPSLPPPPAAPASGPPLSATQIKQEPAEEYETPESPVPPARSPSPPPKVVDV 756
Query: 1402 PNYATINGKVSSPVASGMSS 1421
P++A+ + + + + G +S
Sbjct: 757 PSHASQSARFNKHLDRGFNS 776
Score = 58.5 bits (140), Expect = 5e-08
Identities = 106/428 (24%), Positives = 152/428 (35%), Gaps = 81/428 (18%)
Query: 534 PEALSPLTNGLDKSYPMEPMVNGGGYPYESASRAGPAHAGHTAPMRPSYS---AQEGLAG 590
P +L P ++ S P PM +PY S+S + A + ++ S S A + L
Sbjct: 356 PHSLPPASS----SAPAPPM----RFPYSSSSSSSAAASSSSSSSSSSASPFPASQALPS 407
Query: 591 YQREGP---------------HPAWPQPVTTSHYAHDPSGMFRSQSFSEAEP-QLPPAPV 634
Y P P+ P S P R + S A P PP+
Sbjct: 408 YPHSFPPPTSLSVSNQPPKYTQPSLPSQAVWSQGPPPPPPYGRLLANSNAHPGPFPPSTG 467
Query: 635 RGGSSREAVQRGLNSWQQQQQQQQQPRPPPRQQERAHLESLVASRPSPQPLAETPIPSLP 694
++ V + QQQQQQQQQ + +QQ++ H S P P P P
Sbjct: 468 AQSTAHPPVSTHHHHHQQQQQQQQQQQQQQQQQQQHHGNS------GPPPPGAFPHPLEG 521
Query: 695 EFPRAASQQEIEQSIETLNMLMLDLEPASA-AAPLHKSQSVPGAWPGASPLSSQPLSGS- 752
A + S+ +L P A P H S A P P+SS S S
Sbjct: 522 GSSHHAHPYAMSPSLGSLR----PYPPGPAHLPPPHSQVSYSQAGPNGPPVSSSSNSSSS 577
Query: 753 -SRQSHPLTQSRSGYIPSGHSLGTPEPAP--------RASLESVPPGRSYSPYDYQPCLA 803
S+ S+P + PS G P P P A+L +V + SP Y+
Sbjct: 578 TSQGSYPCSHPS----PSQGPQGAPYPFPPVPTVTTSSATLSTVIATVASSPAGYKTASP 633
Query: 804 GPNQDFHSKSPA-----SSSLPAFLP------TTHSPPGPQ--QPPASLPGLTAQPLLSP 850
+ ++P+ +++ P + P T +PPG + PPA PG P
Sbjct: 634 PGPPPYGKRAPSPGAYKTATPPGYKPGSPPSFRTGTPPGYRGTSPPAG-PG-----TFKP 687
Query: 851 KEATSDPSRTPEEEPLNLEGLVAHRVAGVQAREKQPAEPPAPLRRRAASDGQYENQSPEA 910
T P P P L L A PA P + + E ++PE+
Sbjct: 688 GSPTVGPGPLPPAGPSGLPSLPPPPAA--------PASGPPLSATQIKQEPAEEYETPES 739
Query: 911 TSP--RSP 916
P RSP
Sbjct: 740 PVPPARSP 747
Score = 51.2 bits (121), Expect = 9e-06
Identities = 158/710 (22%), Positives = 233/710 (32%), Gaps = 146/710 (20%)
Query: 761 QSRSGYIPSGHSLGTPEPAPRASLESVPPGRSYSPYDYQPCLAGPNQDFHSKSPASSSLP 820
+SR P G S + + S ++ R + G +++ ++ P
Sbjct: 28 RSRGRASPGGVSTSSSDGKAEKSRQTAKKARVEEASTPKVNKQGRSEEISESESEETNAP 87
Query: 821 AFLPTTHSPPGPQQPPASLPGLTAQPLLSPKEATSDPSRTPEEE-----PLNLEGLVAHR 875
T P PQ P + L L + L + +SDP ++ + G V +
Sbjct: 88 KKTKTEQELPRPQSP-SDLDSLDGRSLND--DGSSDPRDIDQDNRSTSPSIYSPGSVEND 144
Query: 876 VAGVQAREKQPAEP--PAPLRRRAASDGQYENQSPEATSPRSP-----GVRSPVQCVSPE 928
+ PA P P PL + + PEA+ P G +P++ P
Sbjct: 145 SDSSSGLSQGPARPYHPPPLFPPSPQPPDSTPRQPEASFEPHPSVTPTGYHAPME---PP 201
Query: 929 LALTIALNPGGRPKEPHLHSYKEAFEEMEGTSPSSPPPSGVRSPPGLAKTPLSALGLKPH 988
+ PG P P L+ GT GV S P +G K
Sbjct: 202 TSRMFQAPPGAPPPHPQLYP--------GGTG-------GVLSGP--------PMGPKGG 238
Query: 989 NPADILLHPTGVTRRRIQPEEDEGKVVVRLSEEPRSYVESVARTAVAGPRAQDSEPKSFS 1048
A + P G GK P + SV+ + +G A ++P
Sbjct: 239 GAASSVGGPNG------------GK-----QHPPPTTPISVSSSGASG--APPTKP---- 275
Query: 1049 APATQAYGHEIPLRNGTLGGSFVSPS--------PL---STSSPILSADSTSVGSFPSGE 1097
P T G +P V+P+ PL S S P L A G PS
Sbjct: 276 -PTTPVGGGNLPSAPPPANFPHVTPNLPPPPALRPLNNASASPPGLGAQPLP-GHLPSPH 333
Query: 1098 SSDQGPRTPTQPLLESGFRSGSLGQPSPSAQRNYQSSSPLPTVGSSYSSPDYSLQHFSSS 1157
+ QG L G G PSP + SS+P P + YSS S SSS
Sbjct: 334 AMGQGMGG-----LPPGPEKGPTLAPSPHSLPPASSSAPAPPMRFPYSSSSSSSAAASSS 388
Query: 1158 PESQARAQFSVAGVHTVPGSPQARHRTVGTNTPPSPGFGWRAINPSMAAPSSPSLSHHQM 1217
S + + +P P + PP P PS PS +
Sbjct: 389 SSSSSSSASPFPASQALPSYPH--------SFPPPTSLSVSNQPPKYTQPSLPSQAVWS- 439
Query: 1218 MGPPGTGFHGSTVSS--------PQSSAATTPGSPSLCRH----------PAGVYQVSGL 1259
GPP +G +++ P S+ A + P + H Q
Sbjct: 440 QGPPPPPPYGRLLANSNAHPGPFPPSTGAQSTAHPPVSTHHHHHQQQQQQQQQQQQQQQQ 499
Query: 1260 HNKVATTPGSPSLGRHPGAHQGNLASGLHSNAIASPGSPSLGRHLGGSGSVVPGSPCLDR 1319
+ G P G P +G + H A+ SPS LG PG L
Sbjct: 500 QQQHHGNSGPPPPGAFPHPLEGGSSHHAHPYAM----SPS----LGSLRPYPPGPAHLPP 551
Query: 1320 HVAYGGYSTPEDRRPTLSRQSSASGYQAPSTPSFPVSPAYYPGLSSPATSPSPDSAAFRQ 1379
+ YS P +S S++S + S S+P S +P SP+ P Q
Sbjct: 552 PHSQVSYSQAGPNGPPVSSSSNSS--SSTSQGSYPCS---HP---SPSQGP--------Q 595
Query: 1380 GSPTPALPEKRRMSVGDRAGSLPNYATINGKVSSPVASGMSSPSGGSTVS 1429
G+P P P +P T + +S+ +A+ SSP+G T S
Sbjct: 596 GAPYPFPP-------------VPTVTTSSATLSTVIATVASSPAGYKTAS 632
Score = 47.8 bits (112), Expect = 9e-05
Identities = 137/572 (23%), Positives = 185/572 (32%), Gaps = 122/572 (21%)
Query: 533 YPEALSPLTNGLDKSYPMEPMVNGGGYPYESASRAGPAHAG--HTAPMRPSYSAQEGLAG 590
+P+ T G+ PM P GGG +AS G + G H P P + G +G
Sbjct: 216 HPQLYPGGTGGVLSGPPMGP--KGGG----AASSVGGPNGGKQHPPPTTPISVSSSGASG 269
Query: 591 YQREGPHPAWPQPVTTSHYAHDPSGMFRSQSFSEAEPQLPPAP-VRGGSSREAVQRGLNS 649
P P T + PS +F P LPP P +R ++ A GL +
Sbjct: 270 A------PPTKPPTTPVGGGNLPSAP-PPANFPHVTPNLPPPPALRPLNNASASPPGLGA 322
Query: 650 WQQQQQQQQQPRPPPRQQERAHLESLVASRPSPQPLAETPIPSLPEFPRAASQQEIEQSI 709
QP P A + + P P+ T PS P A+S
Sbjct: 323 ---------QPLPGHLPSPHAMGQGMGGLPPGPEK-GPTLAPSPHSLPPASS-------- 364
Query: 710 ETLNMLMLDLEPASAAAPLHKSQSVPGAWPGASPLSSQPLSGSSRQSHPLTQSRSGY--- 766
SA AP + + A+ SS S SS P +Q+ Y
Sbjct: 365 -------------SAPAPPMRFPYSSSSSSSAAASSSSSSSSSSASPFPASQALPSYPHS 411
Query: 767 IPSGHSLGTPEPAPRASLESVPPGRSYS-----PYDYQPCLAGPNQDFHSKSPASSSLPA 821
P SL P+ + S+P +S P Y LA N P++ +
Sbjct: 412 FPPPTSLSVSNQPPKYTQPSLPSQAVWSQGPPPPPPYGRLLANSNAHPGPFPPSTGAQST 471
Query: 822 FLP--TTHSPPGPQQPPASLPGLTAQPLLSPKEATSDPSRTPEEEPLNLEGLVAHR---- 875
P +TH QQ Q S P P P LEG +H
Sbjct: 472 AHPPVSTHHHHHQQQQQQQQQQQQQQQQQQQHHGNSGPP-PPGAFPHPLEGGSSHHAHPY 530
Query: 876 -----VAGVQAREKQPAEPPAPLRR--------------------RAASDGQY--ENQSP 908
+ ++ PA P P + + S G Y + SP
Sbjct: 531 AMSPSLGSLRPYPPGPAHLPPPHSQVSYSQAGPNGPPVSSSSNSSSSTSQGSYPCSHPSP 590
Query: 909 EATSPRSPGVRSPVQCVSPELAL------TIALNPGGRPKEPHLHSYKEAFEEMEGTSPS 962
+P PV V+ A T+A +P G YK A SP
Sbjct: 591 SQGPQGAPYPFPPVPTVTTSSATLSTVIATVASSPAG---------YKTA-------SPP 634
Query: 963 SPPPSGVRSP-PGLAKTPLSALGLKPHNPADILL-HPTGVTRRRIQPEEDEGKVVVRLSE 1020
PPP G R+P PG KT + G KP +P P G R P G +
Sbjct: 635 GPPPYGKRAPSPGAYKT-ATPPGYKPGSPPSFRTGTPPGY--RGTSPPAGPG------TF 685
Query: 1021 EPRSYVESVARTAVAGPRAQDSEPKSFSAPAT 1052
+P S AGP S P +APA+
Sbjct: 686 KPGSPTVGPGPLPPAGPSGLPSLPPPPAAPAS 717
>gi|55750041 atrophin-1 [Homo sapiens]
Length = 1190
Score = 70.9 bits (172), Expect = 1e-11
Identities = 164/740 (22%), Positives = 246/740 (33%), Gaps = 154/740 (20%)
Query: 735 PGAWPGASPLSSQPLSGSSRQSHPLTQSRSGYIPSGHSLGTPEPAPRASLESVPPGRSYS 794
PG+ S SS G +R HP + PS P+ PR S P S +
Sbjct: 138 PGSVENDSDSSSGLSQGPARPYHPPPL----FPPSPQP---PDSTPRQPEASFEPHPSVT 190
Query: 795 PYDYQPCLAGPNQDFHSKSPASSSLPAFLPTTHSPPGPQQPPASLPGLTAQPLLSPKEAT 854
P Y + P P + PP PQ P G+ + P + PK
Sbjct: 191 PTGYHAPMEPPTSRMFQAPPGAP-----------PPHPQLYPGGTGGVLSGPPMGPK--- 236
Query: 855 SDPSRTPEEEPLNLEGLVAHRVAGVQAREKQPAEPPAPLRRRAASDGQYENQSPEATSPR 914
G A V G ++ P P P+ +S G + +P P
Sbjct: 237 --------------GGGAASSVGGPNGGKQHP-PPTTPI--SVSSSG--ASGAPPTKPPT 277
Query: 915 SPGVRSPVQCVSPELALTIALNPGGRPKEPHLHSYKEAFEEMEGTSPSSPPPSGVR---- 970
+P + G P P ++ +P+ PPP +R
Sbjct: 278 TP------------------VGGGNLPSAPPPANFPH-------VTPNLPPPPALRPLNN 312
Query: 971 ---SPPGLAKTPLSALGLKPHNPADILLHPTGVTRRRIQPEEDEGKVVVRLSEEPRSYVE 1027
SPPGL PL H P+ H G + P ++G L+ P S
Sbjct: 313 ASASPPGLGAQPLPG-----HLPSP---HAMGQGMGGLPPGPEKGPT---LAPSPHSLPP 361
Query: 1028 SVARTAVAGPRAQDSEPKSFSAPATQAYGHEIPLRNGTLGGSFVSPSPLSTSSPILSADS 1087
+ + R S S SA A+ + + S SP P S + P
Sbjct: 362 ASSSAPAPPMRFPYSSSSSSSAAASS---------SSSSSSSSASPFPASQALP------ 406
Query: 1088 TSVGSFPSGES---SDQGPRTPTQPLLESGFRSGSLGQPSPSAQRNYQSSS-------PL 1137
+ SFP S S+Q P+ TQP L S S G P P ++S P
Sbjct: 407 SYPHSFPPPTSLSVSNQPPKY-TQPSLPSQ-AVWSQGPPPPPPYGRLLANSNAHPGPFPP 464
Query: 1138 PTVGSSYSSPDYSLQHFSSSPESQARAQFSVAGVHTVPGSPQARHRTVGTNTPPSPGFGW 1197
T S + P S H + Q + Q Q + + G + PP PG
Sbjct: 465 STGAQSTAHPPVSTHHHHHQQQQQQQQQ--------QQQQQQQQQQHHGNSGPPPPGAFP 516
Query: 1198 R-------------AINPSMAA--PSSPSLSH----HQMMGPPGTGFHGSTVSSPQSSAA 1238
A++PS+ + P P +H H + G +G VSS +S++
Sbjct: 517 HPLEGGSSHHAHPYAMSPSLGSLRPYPPGPAHLPPPHSQVSYSQAGPNGPPVSSSSNSSS 576
Query: 1239 TTPGSPSLCRHPAGVYQVSGLHNKVATTPGSPSLGRHPGAHQGNLASGLHSNAIAS-PGS 1297
+T C HP+ G P + +AS AS PG
Sbjct: 577 STSQGSYPCSHPSPSQGPQGAPYPFPPVPTVTTSSATLSTVIATVASSPAGYKTASPPGP 636
Query: 1298 PSLGRHLGGSGS--------VVPGSPCLDRHVAYGGY-STPEDRRPTLSRQSSASGYQAP 1348
P G+ G+ PGSP R GY T P + S + P
Sbjct: 637 PPYGKRAPSPGAYKTATPPGYKPGSPPSFRTGTPPGYRGTSPPAGPGTFKPGSPTVGPGP 696
Query: 1349 STPSFPVS-PAYYPGLSSPATSPSPDSAAFRQ------GSPTPALPEKRRMSVGDRAGSL 1401
P+ P P+ P ++PA+ P + +Q +P +P R S + +
Sbjct: 697 LPPAGPSGLPSLPPPPAAPASGPPLSATQIKQEPAEEYETPESPVPPARSPSPPPKVVDV 756
Query: 1402 PNYATINGKVSSPVASGMSS 1421
P++A+ + + + + G +S
Sbjct: 757 PSHASQSARFNKHLDRGFNS 776
Score = 58.5 bits (140), Expect = 5e-08
Identities = 106/428 (24%), Positives = 152/428 (35%), Gaps = 81/428 (18%)
Query: 534 PEALSPLTNGLDKSYPMEPMVNGGGYPYESASRAGPAHAGHTAPMRPSYS---AQEGLAG 590
P +L P ++ S P PM +PY S+S + A + ++ S S A + L
Sbjct: 356 PHSLPPASS----SAPAPPM----RFPYSSSSSSSAAASSSSSSSSSSASPFPASQALPS 407
Query: 591 YQREGP---------------HPAWPQPVTTSHYAHDPSGMFRSQSFSEAEP-QLPPAPV 634
Y P P+ P S P R + S A P PP+
Sbjct: 408 YPHSFPPPTSLSVSNQPPKYTQPSLPSQAVWSQGPPPPPPYGRLLANSNAHPGPFPPSTG 467
Query: 635 RGGSSREAVQRGLNSWQQQQQQQQQPRPPPRQQERAHLESLVASRPSPQPLAETPIPSLP 694
++ V + QQQQQQQQQ + +QQ++ H S P P P P
Sbjct: 468 AQSTAHPPVSTHHHHHQQQQQQQQQQQQQQQQQQQHHGNS------GPPPPGAFPHPLEG 521
Query: 695 EFPRAASQQEIEQSIETLNMLMLDLEPASA-AAPLHKSQSVPGAWPGASPLSSQPLSGS- 752
A + S+ +L P A P H S A P P+SS S S
Sbjct: 522 GSSHHAHPYAMSPSLGSLR----PYPPGPAHLPPPHSQVSYSQAGPNGPPVSSSSNSSSS 577
Query: 753 -SRQSHPLTQSRSGYIPSGHSLGTPEPAP--------RASLESVPPGRSYSPYDYQPCLA 803
S+ S+P + PS G P P P A+L +V + SP Y+
Sbjct: 578 TSQGSYPCSHPS----PSQGPQGAPYPFPPVPTVTTSSATLSTVIATVASSPAGYKTASP 633
Query: 804 GPNQDFHSKSPA-----SSSLPAFLP------TTHSPPGPQ--QPPASLPGLTAQPLLSP 850
+ ++P+ +++ P + P T +PPG + PPA PG P
Sbjct: 634 PGPPPYGKRAPSPGAYKTATPPGYKPGSPPSFRTGTPPGYRGTSPPAG-PG-----TFKP 687
Query: 851 KEATSDPSRTPEEEPLNLEGLVAHRVAGVQAREKQPAEPPAPLRRRAASDGQYENQSPEA 910
T P P P L L A PA P + + E ++PE+
Sbjct: 688 GSPTVGPGPLPPAGPSGLPSLPPPPAA--------PASGPPLSATQIKQEPAEEYETPES 739
Query: 911 TSP--RSP 916
P RSP
Sbjct: 740 PVPPARSP 747
Score = 51.2 bits (121), Expect = 9e-06
Identities = 158/710 (22%), Positives = 233/710 (32%), Gaps = 146/710 (20%)
Query: 761 QSRSGYIPSGHSLGTPEPAPRASLESVPPGRSYSPYDYQPCLAGPNQDFHSKSPASSSLP 820
+SR P G S + + S ++ R + G +++ ++ P
Sbjct: 28 RSRGRASPGGVSTSSSDGKAEKSRQTAKKARVEEASTPKVNKQGRSEEISESESEETNAP 87
Query: 821 AFLPTTHSPPGPQQPPASLPGLTAQPLLSPKEATSDPSRTPEEE-----PLNLEGLVAHR 875
T P PQ P + L L + L + +SDP ++ + G V +
Sbjct: 88 KKTKTEQELPRPQSP-SDLDSLDGRSLND--DGSSDPRDIDQDNRSTSPSIYSPGSVEND 144
Query: 876 VAGVQAREKQPAEP--PAPLRRRAASDGQYENQSPEATSPRSP-----GVRSPVQCVSPE 928
+ PA P P PL + + PEA+ P G +P++ P
Sbjct: 145 SDSSSGLSQGPARPYHPPPLFPPSPQPPDSTPRQPEASFEPHPSVTPTGYHAPME---PP 201
Query: 929 LALTIALNPGGRPKEPHLHSYKEAFEEMEGTSPSSPPPSGVRSPPGLAKTPLSALGLKPH 988
+ PG P P L+ GT GV S P +G K
Sbjct: 202 TSRMFQAPPGAPPPHPQLYP--------GGTG-------GVLSGP--------PMGPKGG 238
Query: 989 NPADILLHPTGVTRRRIQPEEDEGKVVVRLSEEPRSYVESVARTAVAGPRAQDSEPKSFS 1048
A + P G GK P + SV+ + +G A ++P
Sbjct: 239 GAASSVGGPNG------------GK-----QHPPPTTPISVSSSGASG--APPTKP---- 275
Query: 1049 APATQAYGHEIPLRNGTLGGSFVSPS--------PL---STSSPILSADSTSVGSFPSGE 1097
P T G +P V+P+ PL S S P L A G PS
Sbjct: 276 -PTTPVGGGNLPSAPPPANFPHVTPNLPPPPALRPLNNASASPPGLGAQPLP-GHLPSPH 333
Query: 1098 SSDQGPRTPTQPLLESGFRSGSLGQPSPSAQRNYQSSSPLPTVGSSYSSPDYSLQHFSSS 1157
+ QG L G G PSP + SS+P P + YSS S SSS
Sbjct: 334 AMGQGMGG-----LPPGPEKGPTLAPSPHSLPPASSSAPAPPMRFPYSSSSSSSAAASSS 388
Query: 1158 PESQARAQFSVAGVHTVPGSPQARHRTVGTNTPPSPGFGWRAINPSMAAPSSPSLSHHQM 1217
S + + +P P + PP P PS PS +
Sbjct: 389 SSSSSSSASPFPASQALPSYPH--------SFPPPTSLSVSNQPPKYTQPSLPSQAVWS- 439
Query: 1218 MGPPGTGFHGSTVSS--------PQSSAATTPGSPSLCRH----------PAGVYQVSGL 1259
GPP +G +++ P S+ A + P + H Q
Sbjct: 440 QGPPPPPPYGRLLANSNAHPGPFPPSTGAQSTAHPPVSTHHHHHQQQQQQQQQQQQQQQQ 499
Query: 1260 HNKVATTPGSPSLGRHPGAHQGNLASGLHSNAIASPGSPSLGRHLGGSGSVVPGSPCLDR 1319
+ G P G P +G + H A+ SPS LG PG L
Sbjct: 500 QQQHHGNSGPPPPGAFPHPLEGGSSHHAHPYAM----SPS----LGSLRPYPPGPAHLPP 551
Query: 1320 HVAYGGYSTPEDRRPTLSRQSSASGYQAPSTPSFPVSPAYYPGLSSPATSPSPDSAAFRQ 1379
+ YS P +S S++S + S S+P S +P SP+ P Q
Sbjct: 552 PHSQVSYSQAGPNGPPVSSSSNSS--SSTSQGSYPCS---HP---SPSQGP--------Q 595
Query: 1380 GSPTPALPEKRRMSVGDRAGSLPNYATINGKVSSPVASGMSSPSGGSTVS 1429
G+P P P +P T + +S+ +A+ SSP+G T S
Sbjct: 596 GAPYPFPP-------------VPTVTTSSATLSTVIATVASSPAGYKTAS 632
Score = 47.8 bits (112), Expect = 9e-05
Identities = 137/572 (23%), Positives = 185/572 (32%), Gaps = 122/572 (21%)
Query: 533 YPEALSPLTNGLDKSYPMEPMVNGGGYPYESASRAGPAHAG--HTAPMRPSYSAQEGLAG 590
+P+ T G+ PM P GGG +AS G + G H P P + G +G
Sbjct: 216 HPQLYPGGTGGVLSGPPMGP--KGGG----AASSVGGPNGGKQHPPPTTPISVSSSGASG 269
Query: 591 YQREGPHPAWPQPVTTSHYAHDPSGMFRSQSFSEAEPQLPPAP-VRGGSSREAVQRGLNS 649
P P T + PS +F P LPP P +R ++ A GL +
Sbjct: 270 A------PPTKPPTTPVGGGNLPSAP-PPANFPHVTPNLPPPPALRPLNNASASPPGLGA 322
Query: 650 WQQQQQQQQQPRPPPRQQERAHLESLVASRPSPQPLAETPIPSLPEFPRAASQQEIEQSI 709
QP P A + + P P+ T PS P A+S
Sbjct: 323 ---------QPLPGHLPSPHAMGQGMGGLPPGPEK-GPTLAPSPHSLPPASS-------- 364
Query: 710 ETLNMLMLDLEPASAAAPLHKSQSVPGAWPGASPLSSQPLSGSSRQSHPLTQSRSGY--- 766
SA AP + + A+ SS S SS P +Q+ Y
Sbjct: 365 -------------SAPAPPMRFPYSSSSSSSAAASSSSSSSSSSASPFPASQALPSYPHS 411
Query: 767 IPSGHSLGTPEPAPRASLESVPPGRSYS-----PYDYQPCLAGPNQDFHSKSPASSSLPA 821
P SL P+ + S+P +S P Y LA N P++ +
Sbjct: 412 FPPPTSLSVSNQPPKYTQPSLPSQAVWSQGPPPPPPYGRLLANSNAHPGPFPPSTGAQST 471
Query: 822 FLP--TTHSPPGPQQPPASLPGLTAQPLLSPKEATSDPSRTPEEEPLNLEGLVAHR---- 875
P +TH QQ Q S P P P LEG +H
Sbjct: 472 AHPPVSTHHHHHQQQQQQQQQQQQQQQQQQQHHGNSGPP-PPGAFPHPLEGGSSHHAHPY 530
Query: 876 -----VAGVQAREKQPAEPPAPLRR--------------------RAASDGQY--ENQSP 908
+ ++ PA P P + + S G Y + SP
Sbjct: 531 AMSPSLGSLRPYPPGPAHLPPPHSQVSYSQAGPNGPPVSSSSNSSSSTSQGSYPCSHPSP 590
Query: 909 EATSPRSPGVRSPVQCVSPELAL------TIALNPGGRPKEPHLHSYKEAFEEMEGTSPS 962
+P PV V+ A T+A +P G YK A SP
Sbjct: 591 SQGPQGAPYPFPPVPTVTTSSATLSTVIATVASSPAG---------YKTA-------SPP 634
Query: 963 SPPPSGVRSP-PGLAKTPLSALGLKPHNPADILL-HPTGVTRRRIQPEEDEGKVVVRLSE 1020
PPP G R+P PG KT + G KP +P P G R P G +
Sbjct: 635 GPPPYGKRAPSPGAYKT-ATPPGYKPGSPPSFRTGTPPGY--RGTSPPAGPG------TF 685
Query: 1021 EPRSYVESVARTAVAGPRAQDSEPKSFSAPAT 1052
+P S AGP S P +APA+
Sbjct: 686 KPGSPTVGPGPLPPAGPSGLPSLPPPPAAPAS 717
>gi|239754668 PREDICTED: mucin 12 [Homo sapiens]
Length = 1952
Score = 70.1 bits (170), Expect = 2e-11
Identities = 273/1245 (21%), Positives = 420/1245 (33%), Gaps = 208/1245 (16%)
Query: 375 LHGSTGAVNATRPTL-SATPNHVEHTLSVSSDSGNST------ASTKTDKTDEPVP--GA 425
+H S A T P SAT HVE + + G++ +ST + ++E G+
Sbjct: 397 VHSSPVATATTPPPARSATSGHVEESTAYHRSPGSTQTMHFPESSTTSGHSEESATFHGS 456
Query: 426 SSATAALSPQEKRELDRLLSGFGLEREKQGAMYHTQHLRSRPAGGSAVPSSGRHVVPAQV 485
++ T + +P L L G+ T S G + S H P +
Sbjct: 457 TTHTKSSTPSTTAALAHTSYHSSL-----GSTETTHFRDSSTISGRSEESKASHSSPDAM 511
Query: 486 HVNGGALASERETDILDDELPNQDGHSAGSMGTLS-----SLDGVTNTSEGGYPEALSPL 540
A + ++ D P+ S+GSM T + + G++ S Y SP
Sbjct: 512 ATTV-LPAGSTPSVLVGDSTPSPI--SSGSMETTALPGSTTKPGLSEKSTTFYSSPRSPD 568
Query: 541 TNGLDKSYPMEPMVNGGGYPYESASRAGPAHAGHTAPMRPSYS----AQEGLAGYQREGP 596
T L S + G ES + + HT S + +QE A + GP
Sbjct: 569 TTHLPAS------MTSSGVSEESTTSHSRPGSTHTTAFPGSTTMPGLSQESTASHSSPGP 622
Query: 597 HPAWPQPVTTSHYAHDPS-GMFRSQSFSEAEPQLPP-----------APVR--------- 635
P +T+ + P F S+ S LP PV
Sbjct: 623 TDTTLSPGSTTASSLGPEYTTFHSRPGSTETTLLPDNTTASGLLEASMPVHSSTRSPHTT 682
Query: 636 ----GGSSREAVQRGLNSWQQQQQQQQQPRPPPRQQERAHLESLVASRPSPQPLAETPIP 691
G ++R+ +SW RP P A +E S SP + T I
Sbjct: 683 LSPAGSTTRQGESTTFHSWPSSNDT----RPAPPTTTSAFVEPSTTSHGSPSSIPTTHIS 738
Query: 692 SLPEFPRAASQQEIEQSI---------ETLNMLMLDL-------EPASAAAPLHKSQSVP 735
+ R+ + +E+S +T++ D S ++ H S P
Sbjct: 739 A-----RSTTSGLVEESTTYHSSPGSTQTMHFPESDTTSGRGEESTTSHSSTTHTISSAP 793
Query: 736 GAWPGA--SPLSSQPLSGSSRQSH----PLTQSRSGYIPSGHS----------------- 772
P S GS+ +H T RS + HS
Sbjct: 794 STTSALVEEPTSYHSSPGSTATTHFPDSSTTSGRSEESIASHSSQDATGTIVLPARSTNS 853
Query: 773 --LG--TPEPAPRASLESVP-PGRSYSPYDYQPCLAGPNQDFHS--KSPASSSLPAFLP- 824
LG T P S+E+ PG + +P L+ + FHS +SPA++ PA
Sbjct: 854 VLLGESTTSPISSGSMETTALPGSTTTPG-----LSERSTTFHSSPRSPATTLSPASTTS 908
Query: 825 --------TTHSPPGPQQPPASLPGLTAQPLLSPKEATSDPSRTPEEEPLNLEGLVAHRV 876
T+HS PG A P T P LS TS S + L L +
Sbjct: 909 SGVSEESTTSHSRPGSTHTTA-FPDSTTTPGLSRHSTTSHSSPGSTDTTL-LPASTTTXL 966
Query: 877 AGVQARE--KQPAEPPAPLRRRAASDGQYENQSPEATSPRSPGVR-SPVQCVSPELALTI 933
G + L + G E + +SPRSP SP S ++
Sbjct: 967 VGEPTTSPISSGSTETTALPGSTTTAGLSEKSTTFYSSPRSPDTTLSPASTTSSGVSEE- 1025
Query: 934 ALNPGGRPKEPHLHSYKEAFEEMEGTSPSSPPPSGVRSPPGLAKTPLSALGLKPHN--PA 991
+ RP H ++ + M G S S + S PG T LS + P
Sbjct: 1026 STTSHSRPGSTHTTAFPGS-TTMPGVSQES---TASHSSPGSTDTTLSPRSTTASSLGPE 1081
Query: 992 DILLHP-TGVTRRRIQPEEDEGKVVVRLSE-------EPRSYVESVARTAVAG------- 1036
H G T + P+ ++ S PR+ + T G
Sbjct: 1082 STTFHSGPGSTETTLLPDNTTASGLLEASTPVHSSTGSPRTTLSPAGSTTRQGESTTFQS 1141
Query: 1037 -PRAQDSEP------KSFSAPATQAYGH--EIPLRNGTLGGSFVSPSPLST---SSPILS 1084
P ++D+ P +F +T ++G IP + + + S ST SSP+
Sbjct: 1142 WPSSKDTMPAPPTTTSAFVELSTTSHGSPSSIPTTHFSASSTTFGRSEESTTVHSSPVAP 1201
Query: 1085 AD------STSVGSFPSGESSDQGP-RTPTQPLLESGFRSGSLGQPSPS-AQRNYQSSSP 1136
A ST+ G + P T T ES SG + S + + SSP
Sbjct: 1202 ATTPSPARSTTSGLVEESTAYHSSPGSTQTMHFPESSTASGRSEESRTSHSSTTHTISSP 1261
Query: 1137 LPTVG-------SSYSSP-DYSLQHFSSSPESQARAQFSVAGVHTVPGS----PQARHRT 1184
T S +SSP + HF S + R++ S A H+ P + P H T
Sbjct: 1262 PSTTSALVEEPTSYHSSPGSIATTHFPESSTTSGRSEESTAS-HSSPDTNGITPLPAHFT 1320
Query: 1185 VGTNTPPSPGFGWRAINPSMAAPSSPSLSHHQMMGPPGTGFHGSTVSSPQSSAATTPGSP 1244
S F I+P + S + + T + S+ S Q+ + + S
Sbjct: 1321 TSGRIAESTTF---YISPGSMETTLASTATTPGLSAKSTILYSSSRSPDQTLSPASMTSS 1377
Query: 1245 SLCRHPAGVY-QVSGLHNKV----ATTPG----SPSLGRHPGAHQGNLASG-LHSNAIAS 1294
S+ P +Y Q H TT G S + PG+ + L+ G + +++ A
Sbjct: 1378 SISGEPTSLYSQAESTHTTAFPASTTTSGLSQESTTFHSKPGSTETTLSPGSITTSSFAQ 1437
Query: 1295 PGSPSLGRHLGGSGSVVPGSPCLD--RHVAYGGYSTPEDRRPTLSRQSSASGYQAPSTPS 1352
+ + +V P S + + YS+P T S+ + +
Sbjct: 1438 EFTTPHSQPGSALSTVSPASTTVPGLSEESTTFYSSPGSTETTAFSHSNTMSIHSQQSTP 1497
Query: 1353 FPVSPAYYPGLSSPATSPSPD----SAAFRQGS-PTPALPEKRRMSVGDRAGSLPNYATI 1407
FP SP + + PAT + D S AF S T P R + D G +
Sbjct: 1498 FPDSPGFTHTV-LPATLTTTDIGQESTAFHSSSDATGTTPLPARSTASDLVGEPTTFYIS 1556
Query: 1408 NGKVSSPVASGMSSPSGGSTVSFS-HTLPDFSKYSMPDNSPETRA 1451
+ + SS SG + S + HT P F+ + S ET A
Sbjct: 1557 PSPTYTTLFPASSSTSGLTEESTTFHTSPSFTSTIVSTESLETLA 1601
Score = 58.5 bits (140), Expect = 5e-08
Identities = 262/1229 (21%), Positives = 400/1229 (32%), Gaps = 218/1229 (17%)
Query: 375 LHGSTGAVNATRPTLSATPNHVEHTLSVSSDSGNSTASTKTDKTDEPVPGASSATAALSP 434
+H STG+ + T S+T + E T S S T+ + T V S T SP
Sbjct: 316 VHSSTGSPHTTLSPASSTTHEGEPTTFQSWPSSKDTSPAPSGTTSAFVK--LSTTYHSSP 373
Query: 435 QEKRELDRLLSGFGLEREKQGAMYHTQHLRSRPAGGSAVPSSGRHVVPAQVHVNGGALAS 494
S L ++ H S P + P R V + S
Sbjct: 374 SSTPTTHFSASSTTLGHSEESTPVH-----SSPVATATTPPPARSATSGHVEESTAYHRS 428
Query: 495 ERETDILD-DELPNQDGHSAGSMGTLSSLDGVTNTSEGGYPEALSPLTNGLDKSYPMEPM 553
T + E GHS S ++ G T ++ P + L + S
Sbjct: 429 PGSTQTMHFPESSTTSGHSEES----ATFHGSTTHTKSSTPSTTAALAHTSYHSSLGSTE 484
Query: 554 VNGGGYPYESASRAGPAHAGHTAP------MRPSYSAQEGLAGYQREGPHPAWPQPVT-- 605
+ R+ + A H++P + P+ S L G P + T
Sbjct: 485 TTHFRDSSTISGRSEESKASHSSPDAMATTVLPAGSTPSVLVGDSTPSPISSGSMETTAL 544
Query: 606 ----TSHYAHDPSGMFRSQSFSEAEPQLPPAPVRGGSSREAVQRGLNSWQQQQQQQQQPR 661
T + S F S S LP + G S E+ S +
Sbjct: 545 PGSTTKPGLSEKSTTFYSSPRSPDTTHLPASMTSSGVSEEST----TSHSRPGSTHTTAF 600
Query: 662 PPPRQQERAHLESLVASRPSPQPLAETPIPSL-------PEFPRAASQQEIEQSIETLNM 714
P ES AS SP P T P PE+ S+ T
Sbjct: 601 PGSTTMPGLSQES-TASHSSPGPTDTTLSPGSTTASSLGPEYTTFHSRPG-----STETT 654
Query: 715 LMLDLEPAS----AAAPLHKSQSVPGAWPGASPLSSQPLSGSSRQSH-----------PL 759
L+ D AS A+ P+H S P SP S G S H P
Sbjct: 655 LLPDNTTASGLLEASMPVHSSTRSPHTT--LSPAGSTTRQGESTTFHSWPSSNDTRPAPP 712
Query: 760 TQSRSGYIPSGHSLGTPE--PAPRASLESVPPGRSYSPYDYQPCLAGPNQDFH-SKSPAS 816
T + + PS S G+P P S S G Y G Q H +S +
Sbjct: 713 TTTSAFVEPSTTSHGSPSSIPTTHISARSTTSGLVEESTTYHSS-PGSTQTMHFPESDTT 771
Query: 817 SSLPAFLPTTHSPPGPQQPPASLPGLTAQPLLSPKEATSDPSRT-----PEEEPLN---L 868
S T+HS +S P T+ + P S P T P+ +
Sbjct: 772 SGRGEESTTSHS--STTHTISSAPSTTSALVEEPTSYHSSPGSTATTHFPDSSTTSGRSE 829
Query: 869 EGLVAHRVAGVQAREKQPAEPPAPLRRRAASDGQYENQSPEAT----SPRSPGV------ 918
E + +H PA + ++ + S E T S +PG+
Sbjct: 830 ESIASHSSQDATGTIVLPARSTNSVLLGESTTSPISSGSMETTALPGSTTTPGLSERSTT 889
Query: 919 -----RSPVQCVSPELALTIALNPGG-----RPKEPHLHSYKEA-----FEEMEGTSPSS 963
RSP +SP + ++ RP H ++ ++ TS SS
Sbjct: 890 FHSSPRSPATTLSPASTTSSGVSEESTTSHSRPGSTHTTAFPDSTTTPGLSRHSTTSHSS 949
Query: 964 PPPSGVRSPPGLAKTPLSALGLKPHNPADILLHPTGVTRRRIQPEEDEGKVVVRLSEEPR 1023
P + P T L +G +P +G T P LSE+
Sbjct: 950 PGSTDTTLLPASTTTXL--VGEPTTSPIS-----SGSTETTALPGST---TTAGLSEKST 999
Query: 1024 SYVESVARTAVAGPRAQDSEPKSFSAPATQAYGHEIPLRNGTLGGSFVSPSPLSTSSPIL 1083
++ S PR+ D+ S ++ + E + G + + P ST+ P +
Sbjct: 1000 TFYSS--------PRSPDTT-LSPASTTSSGVSEESTTSHSRPGSTHTTAFPGSTTMPGV 1050
Query: 1084 SADSTSVGSFPSGESSDQGPRTPTQPLL---ESGFRSG------SLGQPSPSAQRNYQSS 1134
S +ST+ S P + PR+ T L + F SG +L + +A ++S
Sbjct: 1051 SQESTASHSSPGSTDTTLSPRSTTASSLGPESTTFHSGPGSTETTLLPDNTTASGLLEAS 1110
Query: 1135 SPLPTVGSSYSSPDYSLQHFSSSPESQARAQFS--VAGVHTVPGSPQARHRTVGTNT--- 1189
+P V SS SP +L S+ F + T+P P V +T
Sbjct: 1111 TP---VHSSTGSPRTTLSPAGSTTRQGESTTFQSWPSSKDTMPAPPTTTSAFVELSTTSH 1167
Query: 1190 ------------PPSPGFG----WRAINPSMAAPS---SPSLSHHQMMGPPGTGFHGS-- 1228
S FG ++ S AP+ SP+ S + T +H S
Sbjct: 1168 GSPSSIPTTHFSASSTTFGRSEESTTVHSSPVAPATTPSPARSTTSGLVEESTAYHSSPG 1227
Query: 1229 ---TVSSPQSSAATTPGSPSLCRHPAGVYQVSGLHNKVA----------TTPGSPSLGRH 1275
T+ P+SS A+ S H + + +S + + ++PGS +
Sbjct: 1228 STQTMHFPESSTASGRSEESRTSHSSTTHTISSPPSTTSALVEEPTSYHSSPGSIATTHF 1287
Query: 1276 PGAHQGNLASGLHSNAIASPGSPS------LGRHLGGSGSVVPGSPCLDRHVAYGGYSTP 1329
P + + SG + AS SP L H SG + + Y +P
Sbjct: 1288 P---ESSTTSGRSEESTASHSSPDTNGITPLPAHFTTSGRIAESTTF---------YISP 1335
Query: 1330 EDRRPTLSRQSSASGYQAPST--------PSFPVSPAYYPGLSSPATSPSPDS------- 1374
TL+ ++ G A ST P +SPA ++S + S P S
Sbjct: 1336 GSMETTLASTATTPGLSAKSTILYSSSRSPDQTLSPA---SMTSSSISGEPTSLYSQAES 1392
Query: 1375 ---AAFRQGSPTPALPEKRRMSVGDRAGSLPNYATINGKVSSPVASGMSSP-----SGGS 1426
AF + T L ++ + + GS + +S A ++P S S
Sbjct: 1393 THTTAFPASTTTSGLSQE-STTFHSKPGSTETTLSPGSITTSSFAQEFTTPHSQPGSALS 1451
Query: 1427 TVS-FSHTLPDFSK-----YSMPDNSPET 1449
TVS S T+P S+ YS P ++ T
Sbjct: 1452 TVSPASTTVPGLSEESTTFYSSPGSTETT 1480
Score = 40.0 bits (92), Expect = 0.020
Identities = 108/448 (24%), Positives = 152/448 (33%), Gaps = 113/448 (25%)
Query: 1075 PLSTSSPILSADSTSVGSFPSGESSDQGP-----------------------------RT 1105
P ST+ P +S +ST+ S P + P T
Sbjct: 245 PDSTTMPGVSQESTASHSIPGSTDTTLSPGTTTPSSLGPESTTFHSSPGYTKTTRLPDNT 304
Query: 1106 PTQPLLESGFR-SGSLGQP----SPSAQRNYQ-------------SSSPLPTVGSS---- 1143
T LLE+ S G P SP++ ++ +SP P+ +S
Sbjct: 305 TTSGLLEASTPVHSSTGSPHTTLSPASSTTHEGEPTTFQSWPSSKDTSPAPSGTTSAFVK 364
Query: 1144 -----YSSPDYS-LQHFSSSPESQARAQFSV----AGVHTVPGSPQARHRTVG-----TN 1188
+SSP + HFS+S + ++ S + V T P AR T G T
Sbjct: 365 LSTTYHSSPSSTPTTHFSASSTTLGHSEESTPVHSSPVATATTPPPARSATSGHVEESTA 424
Query: 1189 TPPSPGFGWRAINPSMAAPSSPSLSHHQMMGPPGTGFHGSTVSSPQSSAATTPGSPSLCR 1248
SPG +M P S + S H FHGST + S+ +TT
Sbjct: 425 YHRSPG-----STQTMHFPESSTTSGH---SEESATFHGSTTHTKSSTPSTTAALAHTSY 476
Query: 1249 HPA----------GVYQVSGLHNKVATTPGSPSLGRHPGAHQGNLASGLHSNAIASPGSP 1298
H + +SG + + SP G+ S L ++ SP S
Sbjct: 477 HSSLGSTETTHFRDSSTISGRSEESKASHSSPDAMATTVLPAGSTPSVLVGDSTPSPISS 536
Query: 1299 SLGRHLGGSGSVV-PGSPCLDRHVAYGGYSTPEDRRPT-LSRQSSASGYQAPSTPS---- 1352
GS PG ++ + YS+P T L ++SG ST S
Sbjct: 537 GSMETTALPGSTTKPG--LSEKSTTF--YSSPRSPDTTHLPASMTSSGVSEESTTSHSRP 592
Query: 1353 -------FPVSPAYYPGLSSPAT----SPSPDSAAFRQGSPTPALPEKRRMSVGDRAGS- 1400
FP S PGLS +T SP P GS T + + R GS
Sbjct: 593 GSTHTTAFPGSTT-MPGLSQESTASHSSPGPTDTTLSPGSTTASSLGPEYTTFHSRPGST 651
Query: 1401 ----LPNYATING--KVSSPVASGMSSP 1422
LP+ T +G + S PV S SP
Sbjct: 652 ETTLLPDNTTASGLLEASMPVHSSTRSP 679
>gi|115298682 HBxAg transactivated protein 2 [Homo sapiens]
Length = 2817
Score = 69.7 bits (169), Expect = 2e-11
Identities = 198/961 (20%), Positives = 333/961 (34%), Gaps = 152/961 (15%)
Query: 387 PTLSATPNHVEHTLSVSSD-SGNSTAS-TKTDKTDEPVPGASSATAALSPQEKRELDRLL 444
PT N + ++ D SGN T + + +D+ +A+ + E+RE D
Sbjct: 1456 PTNGTVNNVAQEPVNTLGDISGNKTPDLSNQNSSDQANEEWETASESSDFNERRERD--- 1512
Query: 445 SGFGLEREKQGAMYHTQHLRSRPAGGSAVPSSGRHVVPAQVHVNGGALASERETDILDDE 504
EK+ A + Q V G +V+P + + + +S+R D
Sbjct: 1513 -------EKKNADLNAQ----------TVVKVGENVLPPKREIAKRSFSSQRPVD----- 1550
Query: 505 LPNQDGHSAGSMGTLSSLDGVTNTSEGGYPEALSPLTNGLDKSYPMEPMVNGGGYPYESA 564
N+ G++ G + + G N G P +G + +P G +
Sbjct: 1551 RQNRRGNN-GPPKSGRNFSGPRNERRSGPPSK-----SGKRGPFDDQPAGTTGVDLINGS 1604
Query: 565 SRAGPAHAGHTAPMRPSYSAQEGLAGYQREGPHPAWPQP---------VTTSHYA----- 610
S AH P + G +RE P P +P ++YA
Sbjct: 1605 S----AHHQEGVPNGTGQKNSKDSTGKKREDPKPGPKKPKEKVDALSQFDLNNYASVVII 1660
Query: 611 ---------HDPSGMFRSQSFSEAEPQLPPAPVRGGSSREAVQRGLNSWQQQQQQQ---- 657
DP F+E + ++ R+ ++ + W ++ +
Sbjct: 1661 DDHPEVTVIEDPQSNLNDDGFTEVVSKKQQKRLQDEERRKKEEQVIQVWNKKNANEKGRS 1720
Query: 658 QQPRPPPR--QQERAHLESLVASRPSPQPLAETPIP-SLPEFPRAASQQEIEQSIETLNM 714
Q + PPR +++ ++ +S P PLA P+P S A++ + ++ +
Sbjct: 1721 QTSKLPPRFAKKQATGIQQAQSSASVP-PLASAPLPPSTSASVPASTSAPLPATLTPVPA 1779
Query: 715 LMLDLEPASAAAPLHKSQSVPGAWPGASPLSSQPLSGSSRQSHPLTQSRSGYIPSGHSLG 774
PAS AP+ S S P ASPL+ S S S P + S + S
Sbjct: 1780 STSAPVPASTLAPVLASTSAPVP---ASPLAPVSASASVSASVPASTSAAAITSSSAPAS 1836
Query: 775 TPEPAPRASLESVPPGRSYSPYDYQPCLAGPNQDFHSKSPASSSLPAFLPTTHSPPGP-- 832
P P P + S P + P LA + AS+S P P SP P
Sbjct: 1837 APAPTPILASVSTPASVTILASASIPILAS--------ALASTSAPTPAPAASSPAAPVI 1888
Query: 833 --QQPPASLPGLTAQPLLSPKEATSDPSRTPEEEPLNLEGLVAHRVAGVQAREKQPAEPP 890
PAS P TA L+P A++ P P++ A QA+ +P + P
Sbjct: 1889 TAPTIPASAP--TASVPLAPASASAP---APAPTPVSAPNPAPPAPAQTQAQTHKPVQNP 1943
Query: 891 APLRRRAASDGQYENQSPEATSPRSPG-VRSPVQCVSPELALTIALNPGGRPKEPHLHSY 949
+++ + P A +P V S +P+ T+ P
Sbjct: 1944 LQTTSQSSKQPPPSIRLPSAQTPNGTDYVASGKSIQTPQSHGTLTAELWDNKVAPPA-VL 2002
Query: 950 KEAFEEMEGTSPSSPPPSGVRSPP--GLAKTPLSALGLKPHNPADILLHPTGVTRRRIQP 1007
+ +++ SP PP + P P S+ G K + + + +
Sbjct: 2003 NDISKKLGPISPPQPPSVSAWNKPLTSFGSAP-SSEGAKNGQESGLEIGTDTIQFGAPAS 2061
Query: 1008 EEDEGKVVVRLSEEPRSYVESVARTAVAGPRA--------QDSEPKSFSAPATQAYGHEI 1059
+E +VV LSE+ + PRA D P G E
Sbjct: 2062 NGNENEVVPVLSEKSADKIPEPKEQRQKQPRAGPIKAQKLPDLSPVENKEHKPGPIGKER 2121
Query: 1060 PLRNGTL---------GGSFVSPSPLSTSSPILSAD-------STSVGSFPSGESSDQGP 1103
L+N + G SP+ + ++ P+ + + ST +G+ S S++ G
Sbjct: 2122 SLKNRKVKDAQQVEPEGQEKPSPATVRSTDPVTTKETKAVSEMSTEIGTMISVSSAEYGT 2181
Query: 1104 RTPTQPLLESGFRSGSLGQPSPSAQRNYQ------SSSPLPTVGSSYSSPDYSLQHFSSS 1157
+ + + S P+ A N + ++ PLP ++ P SSS
Sbjct: 2182 NAKESV---TDYTTPSSSLPNTVATNNTKMEDTLVNNVPLP---NTLPLPKRETIQQSSS 2235
Query: 1158 PESQARAQFSV-----AGVHTVPGSPQARHR-TVGTNTPPSPGFGWRAINPSMAAPSSPS 1211
S FS+ + SP R + + T+T P G ++ S + PS+ +
Sbjct: 2236 LTSVPPTTFSLTFKMESARKAWENSPNVREKGSPVTSTAPPIATG---VSSSASGPSTAN 2292
Query: 1212 LSHHQMMGPPGTGFHGSTVSSPQSSAATTPGSPSLCRHPAGVYQVSGLHNKVATTPGSPS 1271
+ S+ S PQ A+ + SL AG Y S L K TT P+
Sbjct: 2293 YNSF------------SSASMPQIPVASVTPTASLSG--AGTYTTSSLSTKSTTTSDPPN 2338
Query: 1272 L 1272
+
Sbjct: 2339 I 2339
Score = 40.8 bits (94), Expect = 0.012
Identities = 69/300 (23%), Positives = 108/300 (36%), Gaps = 41/300 (13%)
Query: 1013 KVVVRLSEEPRSYVESVARTAVAGPRAQDSEPKSFSAPATQAYGHEIPLRNGTLGGSFVS 1072
K+ R +++ + ++ +A P A P S SA + +P + S +
Sbjct: 1724 KLPPRFAKKQATGIQQAQSSASVPPLASAPLPPSTSASVPASTSAPLPATLTPVPASTSA 1783
Query: 1073 PSPLSTSSPILSADSTSVGSFP------SGESSDQGPRTPTQPLLESGFRSGSLGQPSP- 1125
P P ST +P+L++ S V + P S S P + + + S S P+P
Sbjct: 1784 PVPASTLAPVLASTSAPVPASPLAPVSASASVSASVPASTSAAAITSSSAPASAPAPTPI 1843
Query: 1126 ------SAQRNYQSSSPLPTVGSSYSSPDYSLQHFSSSPESQARAQFSVAGVHTVPGSPQ 1179
A +S+ +P + S+ +S +S+P A A V T P P
Sbjct: 1844 LASVSTPASVTILASASIPILASALAS--------TSAPTPAPAASSPAAPVITAPTIPA 1895
Query: 1180 ARHRTVGTNTPPSPGFGWRAINPSMA---APSSPSLSHHQMMGPPGTGFHGSTVSSPQSS 1236
+ P S A P A AP +P+ + Q P ++ SS Q
Sbjct: 1896 SAPTASVPLAPASASAPAPAPTPVSAPNPAPPAPAQTQAQTHKPVQNPLQTTSQSSKQPP 1955
Query: 1237 AATTPGSPSLCRHPAGV-YQVSGLHNKVATTPGSPSLGRHPGAHQGNLASGLHSNAIASP 1295
+ S + P G Y SG K TP S G L + L N +A P
Sbjct: 1956 PSIRLPS---AQTPNGTDYVASG---KSIQTPQS----------HGTLTAELWDNKVAPP 1999
Score = 35.4 bits (80), Expect = 0.49
Identities = 96/467 (20%), Positives = 160/467 (34%), Gaps = 109/467 (23%)
Query: 616 MFRSQSFSEAEPQLPPA-----PVRGGSSREAV--------QRGLNSWQQQQQQQQQPRP 662
+F Q + +E + P P G R AV Q+ L Q+QQ+Q + +
Sbjct: 627 VFTRQDSNRSEKEATPVVHETEPESGSQPRPAVLSGYFKQFQKSLPPRFQRQQEQMKQQQ 686
Query: 663 PPRQQERAHLESLVASRPSPQPLAETPIPSLPEFPRAASQQEIEQSIETLNM-------- 714
+QQ++ L V S+PS + +P P P Q Q + ++
Sbjct: 687 WQQQQQQGVLPQTVPSQPS-----SSTVPPPPHRPLYQPMQPHPQHLASMGFDPRWLMMQ 741
Query: 715 -----LMLDLEPASAAAPLHKSQSVPGAWPGASPLSSQPLSGS-------SRQSHPLTQS 762
M+ PA P+H P + P S S + H ++ S
Sbjct: 742 SYMDPRMMSGRPAMDIPPIHPGMIPPKPLMRRDQMEGSPNSSESFEHIARSARDHAISLS 801
Query: 763 RS----GYIPSGHSLGTPEPAPRASLESVPPGRSYSPYDYQPCLAG-----------PNQ 807
G P H+ P+A+ E RS + D + A P
Sbjct: 802 EPRMLWGSDPYPHAEPQQATTPKAT-EEPEDVRSEAALDQEQITAAYSVEHNQLEAHPKA 860
Query: 808 DFHSKSPASSSLPAFLPTTHSPPGPQQPPASLPGLTAQPLLSPKEATSDPSRTPEEEPLN 867
DF +S + + + FL + P A+ + +P + T P+EE
Sbjct: 861 DFIRES-SEAQVQKFLSRSVEDVRPHHTDANNQSACFE---APDQKTLS---APQEE--- 910
Query: 868 LEGLVAHRVAGVQAREKQPAEPPAPLRRRAASDGQYENQSP-EATSPRSPGV-RSPVQCV 925
R++ V+++ P R+R+ S G Q P E S S G+ + +C+
Sbjct: 911 -------RISAVESQ---------PSRKRSVSHGSNHTQKPDEQRSEPSAGIPKVTSRCI 954
Query: 926 -----------SPELALTIALNPGGRPKEPHLHSYKEAFEEMEGTSPSSPPPSGVRSPPG 974
P+ I + G +P++ YK E G PSS V P
Sbjct: 955 DSKEPIERPEEKPKKEGFIRSSEGPKPEK----VYKSKSETRWGPRPSSNRREEVNDRPV 1010
Query: 975 LAKTPLSALGLKPHNPADILLHPTGVTRRRIQPEEDEGKVVVRLSEE 1021
P+ L+ + R Q +E EG+ +++E+
Sbjct: 1011 RRSGPIKKPVLR------------DMKEEREQRKEKEGEKAEKVTEK 1045
Score = 32.0 bits (71), Expect = 5.4
Identities = 31/115 (26%), Positives = 44/115 (38%), Gaps = 9/115 (7%)
Query: 488 NGGALASERETDILDDELPNQDGHSAGSMGTLSSLDGVTNTSEGGYPEALSPLTNGLDKS 547
+GG A + D++LP QD +AG+ L V G P+A NG +
Sbjct: 180 DGGKAAGSPSSSDQDEKLPGQDESTAGTSEQNDILKVVEKRIACGPPQA---KLNGQQAA 236
Query: 548 YPMEPMVNGGGYPYESASRA--GPAHAGHTAPMRPSYSAQEGLAGYQREGPHPAW 600
+ Y ++ R P H PMR S E G + GP P+W
Sbjct: 237 LASQYRAMMPPYMFQQYPRMTYPPLH----GPMRFPPSLSETNKGLRGRGPPPSW 287
>gi|189181724 proteoglycan 4 isoform D [Homo sapiens]
Length = 1270
Score = 68.6 bits (166), Expect = 5e-11
Identities = 122/600 (20%), Positives = 202/600 (33%), Gaps = 70/600 (11%)
Query: 805 PNQDFHSKSPASSSLPAFLPTTHSPPGPQQPPASLPGLTAQPLLSPKEATSDPSRTPEEE 864
P + +K PA ++ PTT P P P +PKE +++
Sbjct: 199 PKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTT 258
Query: 865 PLNLEGLVAHRVAGVQAREKQP--AEPPAPLRRRAASDGQYENQSPEATSPRSPG---VR 919
P A +E P + PAP ++A E P T+P+ P +
Sbjct: 259 PKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKE---PAPTTPKKPAPTTPK 315
Query: 920 SPVQCVSPELALTIALNPGGRPKEPHLHSYKE----AFEEMEGTSPSSPPPSGVRSP-PG 974
P E T P KEP + KE A ++ T+P P P+ + P P
Sbjct: 316 EPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPT 375
Query: 975 LAKTPLSALGLKPHNPADILLHPTGVTRRRIQPEEDEGKVVVRLSEEPRSYVESVARTAV 1034
K P P PA T + P + P + E T
Sbjct: 376 TTKEPSPT---TPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPK 432
Query: 1035 AGPRAQDSEPKSFSAPATQAYGHEIPLRNGTLGGSFVSPSPLSTSSPILSADSTSVGSFP 1094
+P + + P T + +P + ++P +A +T P
Sbjct: 433 EPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTP 492
Query: 1095 SGESSDQGPRTPTQPLLESGFRSGSLGQPSPSAQRNYQSSSPLPTVGSSYSSPDYSLQHF 1154
+ P TP +P + L +P P PT + ++P+ +
Sbjct: 493 T-TPEKLAPTTPEKP---APTTPEELAPTTPEEPTPTTPEEPAPTTPKA-AAPNTPKEPA 547
Query: 1155 SSSPESQARAQFSVAGVHTVPGSPQARHRTVGTNTPPSPGFGWRAINPSMAAPSSPSLSH 1214
++P+ A P +P+ T T P+ G AP++P
Sbjct: 548 PTTPKEPA------------PTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPA 595
Query: 1215 HQMMGPPGTGFHGSTV------SSPQSSAATTPGSPSLCRHPAGVYQVSGLHNKVATTPG 1268
+ + P T ST ++P+ +A TTP P+ TTP
Sbjct: 596 PKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPA------------------PTTPK 637
Query: 1269 SPSLGRHPGAHQGNLASGLHSNAIASPGSPSLGRHLGGSGSVVPGSPCLDRHVAYGGYST 1328
P+ P +G + L A +P P+ + L + + P S D+ +T
Sbjct: 638 EPA----PTTPKGTAPTTLKEPAPTTPKKPA-PKELAPTTTKGPTSTTSDKPAP----TT 688
Query: 1329 PEDRRPTLSRQSSASGYQ--APSTPSFPVSPAYYPGLSSPATSPSPDSAAFRQGSPTPAL 1386
P++ PT ++ + + + AP+TP P P +S+P T+ P + TP L
Sbjct: 689 PKETAPTTPKEPAPTTPKKPAPTTPETP--PPTTSEVSTPTTTKEPTTIHKSPDESTPEL 746
Score = 67.0 bits (162), Expect = 2e-10
Identities = 164/821 (19%), Positives = 273/821 (33%), Gaps = 138/821 (16%)
Query: 660 PRPPPRQQERAHLESLVASRPS-PQPLAETPIPSLPEFPRAASQQEIEQSIETLNMLMLD 718
P+ P + + + S P+ P+ A T S P P+ + ++ T
Sbjct: 221 PKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPK---- 276
Query: 719 LEPASAAAPLHKSQSVPGAWPGASPLSSQPLSGSSRQSHPLTQSRSGYIPSGHSLGTP-E 777
EPA P + P A +P + ++ P T P + TP E
Sbjct: 277 -EPA----PTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTT-------PKEPAPTTPKE 324
Query: 778 PAPRASLESVPPGRSYSPYD-YQPCLAGPNQDFHS--KSPASSSLPAFLPTTHSPPGPQQ 834
P P E P + +P +P P + + K PA ++ PTT P P
Sbjct: 325 PTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTT 384
Query: 835 P--PA-----SLPGLTAQPL--------LSPKE----ATSDPSRTPEEEPLNLEGLVAHR 875
P PA S P T +P +PKE T +P+ T +EP +
Sbjct: 385 PKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEP---APTTPKK 441
Query: 876 VAGVQAREKQPAEPPAPLRRRAASDGQYENQSPEATSPRSPGVRSPVQC--VSPE-LALT 932
A +E P P P + P T+P+ +P + +PE LA T
Sbjct: 442 PAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPT 501
Query: 933 IALNPGGRPKEPHLHSYKEAFEEMEGTSPSSPPPSGVRSPPGLAKTPLSALGLKPHNPAD 992
P P P EE+ T+P P P+ P TP +A P PA
Sbjct: 502 TPEKPA--PTTP---------EELAPTTPEEPTPTTPEEP--APTTPKAAAPNTPKEPAP 548
Query: 993 IL---------LHPTGVTRRRIQPEEDEGKVVVRLSEEPRSYVESVARTAVAGPRAQDSE 1043
P T + P +G L E A T P ++
Sbjct: 549 TTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEP--------APTTPKKPAPKELA 600
Query: 1044 PKSFSAPATQAYGHEIPLR-NGTLGGSFVSPSPLSTSSPILSADSTSVGSFPSGESSDQG 1102
P + P + P GT + P+P + P A +T G+ P+ +
Sbjct: 601 PTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEP---APTTPKGTAPT-TLKEPA 656
Query: 1103 PRTPTQ-------PLLESGFRSGSLGQPSPSAQRNYQSSSPLPTVGSSYSSPDYSLQHFS 1155
P TP + P G S + +P+P+ + ++P ++ P
Sbjct: 657 PTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKP------AP 710
Query: 1156 SSPESQARAQFSVAGVHTVPGSPQARHRTVGTNTP-----PSPGFGWRAINPSMAAPSSP 1210
++PE+ V+ T P H++ +TP P+P +A+ S P P
Sbjct: 711 TTPETPPPTTSEVS-TPTTTKEPTTIHKSPDESTPELSAEPTP----KALENSPKEPGVP 765
Query: 1211 SLSHHQMMGP--PGTGFHGSTVSSPQSSAATTPGSPSLCRHPAGVYQVSGLHNKVATTPG 1268
+ P T +T +++ TT +P + + A + + ATT
Sbjct: 766 TTKTPAATKPEMTTTAKDKTTERDLRTTPETTTAAPKMTKETATTTEKTTESKITATTTQ 825
Query: 1269 SPSLGRHPGAHQGNLASGLHSNAIASPGSPSLGRHLGGSGSVVPGSPCLDR--------- 1319
S I + + +L + + + + +++
Sbjct: 826 VTS----------TTTQDTTPFKITTLKTTTLAPKVTTTKKTITTTEIMNKPEETAKPKD 875
Query: 1320 HVAYGGYSTPEDRRPTLSRQSSASGYQAPSTPSFPVSPAYYPGLSSPATSPSPD--SAAF 1377
+TP+ ++PT +AP P+ P P + P T+P+P ++
Sbjct: 876 RATNSKATTPKPQKPT----------KAPKKPTSTKKPKTMPRVRKPKTTPTPRKMTSTM 925
Query: 1378 RQGSPTPALPEKRRMSVGDRAGSLPNYATINGKVSSPVASG 1418
+ +PT + E + R PN + S A G
Sbjct: 926 PELNPTSRIAE-AMLQTTTRPNQTPNSKLVEVNPKSEDAGG 965
Score = 40.4 bits (93), Expect = 0.015
Identities = 62/307 (20%), Positives = 105/307 (34%), Gaps = 23/307 (7%)
Query: 569 PAHAGHTAPMRPSYSAQEGLAGYQREGPHPAWP-QPVTTSHYAHDPSGMFRSQSFSEAEP 627
P T P +P+ + E LA E P P P +P T+ A P+ + EP
Sbjct: 495 PEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEP 554
Query: 628 ----QLPPAPVRGGSSREAVQRGLNSWQQQQQQQQQPRPPPRQQERAHLESLVASRPSPQ 683
PAP + +G ++ P+ P ++ S +
Sbjct: 555 APTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDK 614
Query: 684 PLAETP---IPSLPEFPRAASQQEIEQSIE--TLNMLMLDLEPASAAAPLHKSQSVPGAW 738
P TP P+ P+ P + +E + T + + P + P K +
Sbjct: 615 PAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTK 674
Query: 739 PGASPLSSQPLSGSSRQSHPLT-QSRSGYIPSGHSLGTPEPAPRASLESVPPGRSYSPYD 797
S S +P + +++ P T + + P + TPE P + E P + P
Sbjct: 675 GPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTT 734
Query: 798 YQPCLAGPNQDFHSKSPASSSLPAFLPTTHSPPGPQQPPASLPGLTAQPLLSPKEATSDP 857
P++ +P S+ P +SP P P P T P+ T+
Sbjct: 735 IH---KSPDE----STPELSAEPTPKALENSPKEPGVPTTKTPAAT-----KPEMTTTAK 782
Query: 858 SRTPEEE 864
+T E +
Sbjct: 783 DKTTERD 789
>gi|189181722 proteoglycan 4 isoform C [Homo sapiens]
Length = 1311
Score = 68.6 bits (166), Expect = 5e-11
Identities = 122/600 (20%), Positives = 202/600 (33%), Gaps = 70/600 (11%)
Query: 805 PNQDFHSKSPASSSLPAFLPTTHSPPGPQQPPASLPGLTAQPLLSPKEATSDPSRTPEEE 864
P + +K PA ++ PTT P P P +PKE +++
Sbjct: 240 PKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTT 299
Query: 865 PLNLEGLVAHRVAGVQAREKQP--AEPPAPLRRRAASDGQYENQSPEATSPRSPG---VR 919
P A +E P + PAP ++A E P T+P+ P +
Sbjct: 300 PKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKE---PAPTTPKKPAPTTPK 356
Query: 920 SPVQCVSPELALTIALNPGGRPKEPHLHSYKE----AFEEMEGTSPSSPPPSGVRSP-PG 974
P E T P KEP + KE A ++ T+P P P+ + P P
Sbjct: 357 EPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPT 416
Query: 975 LAKTPLSALGLKPHNPADILLHPTGVTRRRIQPEEDEGKVVVRLSEEPRSYVESVARTAV 1034
K P P PA T + P + P + E T
Sbjct: 417 TTKEPSPT---TPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPK 473
Query: 1035 AGPRAQDSEPKSFSAPATQAYGHEIPLRNGTLGGSFVSPSPLSTSSPILSADSTSVGSFP 1094
+P + + P T + +P + ++P +A +T P
Sbjct: 474 EPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTP 533
Query: 1095 SGESSDQGPRTPTQPLLESGFRSGSLGQPSPSAQRNYQSSSPLPTVGSSYSSPDYSLQHF 1154
+ P TP +P + L +P P PT + ++P+ +
Sbjct: 534 T-TPEKLAPTTPEKP---APTTPEELAPTTPEEPTPTTPEEPAPTTPKA-AAPNTPKEPA 588
Query: 1155 SSSPESQARAQFSVAGVHTVPGSPQARHRTVGTNTPPSPGFGWRAINPSMAAPSSPSLSH 1214
++P+ A P +P+ T T P+ G AP++P
Sbjct: 589 PTTPKEPA------------PTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPA 636
Query: 1215 HQMMGPPGTGFHGSTV------SSPQSSAATTPGSPSLCRHPAGVYQVSGLHNKVATTPG 1268
+ + P T ST ++P+ +A TTP P+ TTP
Sbjct: 637 PKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPA------------------PTTPK 678
Query: 1269 SPSLGRHPGAHQGNLASGLHSNAIASPGSPSLGRHLGGSGSVVPGSPCLDRHVAYGGYST 1328
P+ P +G + L A +P P+ + L + + P S D+ +T
Sbjct: 679 EPA----PTTPKGTAPTTLKEPAPTTPKKPA-PKELAPTTTKGPTSTTSDKPAP----TT 729
Query: 1329 PEDRRPTLSRQSSASGYQ--APSTPSFPVSPAYYPGLSSPATSPSPDSAAFRQGSPTPAL 1386
P++ PT ++ + + + AP+TP P P +S+P T+ P + TP L
Sbjct: 730 PKETAPTTPKEPAPTTPKKPAPTTPETP--PPTTSEVSTPTTTKEPTTIHKSPDESTPEL 787
Score = 67.0 bits (162), Expect = 2e-10
Identities = 164/821 (19%), Positives = 273/821 (33%), Gaps = 138/821 (16%)
Query: 660 PRPPPRQQERAHLESLVASRPS-PQPLAETPIPSLPEFPRAASQQEIEQSIETLNMLMLD 718
P+ P + + + S P+ P+ A T S P P+ + ++ T
Sbjct: 262 PKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPK---- 317
Query: 719 LEPASAAAPLHKSQSVPGAWPGASPLSSQPLSGSSRQSHPLTQSRSGYIPSGHSLGTP-E 777
EPA P + P A +P + ++ P T P + TP E
Sbjct: 318 -EPA----PTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTT-------PKEPAPTTPKE 365
Query: 778 PAPRASLESVPPGRSYSPYD-YQPCLAGPNQDFHS--KSPASSSLPAFLPTTHSPPGPQQ 834
P P E P + +P +P P + + K PA ++ PTT P P
Sbjct: 366 PTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTT 425
Query: 835 P--PA-----SLPGLTAQPL--------LSPKE----ATSDPSRTPEEEPLNLEGLVAHR 875
P PA S P T +P +PKE T +P+ T +EP +
Sbjct: 426 PKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEP---APTTPKK 482
Query: 876 VAGVQAREKQPAEPPAPLRRRAASDGQYENQSPEATSPRSPGVRSPVQC--VSPE-LALT 932
A +E P P P + P T+P+ +P + +PE LA T
Sbjct: 483 PAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPT 542
Query: 933 IALNPGGRPKEPHLHSYKEAFEEMEGTSPSSPPPSGVRSPPGLAKTPLSALGLKPHNPAD 992
P P P EE+ T+P P P+ P TP +A P PA
Sbjct: 543 TPEKPA--PTTP---------EELAPTTPEEPTPTTPEEP--APTTPKAAAPNTPKEPAP 589
Query: 993 IL---------LHPTGVTRRRIQPEEDEGKVVVRLSEEPRSYVESVARTAVAGPRAQDSE 1043
P T + P +G L E A T P ++
Sbjct: 590 TTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEP--------APTTPKKPAPKELA 641
Query: 1044 PKSFSAPATQAYGHEIPLR-NGTLGGSFVSPSPLSTSSPILSADSTSVGSFPSGESSDQG 1102
P + P + P GT + P+P + P A +T G+ P+ +
Sbjct: 642 PTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEP---APTTPKGTAPT-TLKEPA 697
Query: 1103 PRTPTQ-------PLLESGFRSGSLGQPSPSAQRNYQSSSPLPTVGSSYSSPDYSLQHFS 1155
P TP + P G S + +P+P+ + ++P ++ P
Sbjct: 698 PTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKP------AP 751
Query: 1156 SSPESQARAQFSVAGVHTVPGSPQARHRTVGTNTP-----PSPGFGWRAINPSMAAPSSP 1210
++PE+ V+ T P H++ +TP P+P +A+ S P P
Sbjct: 752 TTPETPPPTTSEVS-TPTTTKEPTTIHKSPDESTPELSAEPTP----KALENSPKEPGVP 806
Query: 1211 SLSHHQMMGP--PGTGFHGSTVSSPQSSAATTPGSPSLCRHPAGVYQVSGLHNKVATTPG 1268
+ P T +T +++ TT +P + + A + + ATT
Sbjct: 807 TTKTPAATKPEMTTTAKDKTTERDLRTTPETTTAAPKMTKETATTTEKTTESKITATTTQ 866
Query: 1269 SPSLGRHPGAHQGNLASGLHSNAIASPGSPSLGRHLGGSGSVVPGSPCLDR--------- 1319
S I + + +L + + + + +++
Sbjct: 867 VTS----------TTTQDTTPFKITTLKTTTLAPKVTTTKKTITTTEIMNKPEETAKPKD 916
Query: 1320 HVAYGGYSTPEDRRPTLSRQSSASGYQAPSTPSFPVSPAYYPGLSSPATSPSPD--SAAF 1377
+TP+ ++PT +AP P+ P P + P T+P+P ++
Sbjct: 917 RATNSKATTPKPQKPT----------KAPKKPTSTKKPKTMPRVRKPKTTPTPRKMTSTM 966
Query: 1378 RQGSPTPALPEKRRMSVGDRAGSLPNYATINGKVSSPVASG 1418
+ +PT + E + R PN + S A G
Sbjct: 967 PELNPTSRIAE-AMLQTTTRPNQTPNSKLVEVNPKSEDAGG 1006
Score = 40.4 bits (93), Expect = 0.015
Identities = 62/307 (20%), Positives = 105/307 (34%), Gaps = 23/307 (7%)
Query: 569 PAHAGHTAPMRPSYSAQEGLAGYQREGPHPAWP-QPVTTSHYAHDPSGMFRSQSFSEAEP 627
P T P +P+ + E LA E P P P +P T+ A P+ + EP
Sbjct: 536 PEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEP 595
Query: 628 ----QLPPAPVRGGSSREAVQRGLNSWQQQQQQQQQPRPPPRQQERAHLESLVASRPSPQ 683
PAP + +G ++ P+ P ++ S +
Sbjct: 596 APTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDK 655
Query: 684 PLAETP---IPSLPEFPRAASQQEIEQSIE--TLNMLMLDLEPASAAAPLHKSQSVPGAW 738
P TP P+ P+ P + +E + T + + P + P K +
Sbjct: 656 PAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTK 715
Query: 739 PGASPLSSQPLSGSSRQSHPLT-QSRSGYIPSGHSLGTPEPAPRASLESVPPGRSYSPYD 797
S S +P + +++ P T + + P + TPE P + E P + P
Sbjct: 716 GPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTT 775
Query: 798 YQPCLAGPNQDFHSKSPASSSLPAFLPTTHSPPGPQQPPASLPGLTAQPLLSPKEATSDP 857
P++ +P S+ P +SP P P P T P+ T+
Sbjct: 776 IH---KSPDE----STPELSAEPTPKALENSPKEPGVPTTKTPAAT-----KPEMTTTAK 823
Query: 858 SRTPEEE 864
+T E +
Sbjct: 824 DKTTERD 830
>gi|189181720 proteoglycan 4 isoform B [Homo sapiens]
Length = 1363
Score = 68.6 bits (166), Expect = 5e-11
Identities = 122/600 (20%), Positives = 202/600 (33%), Gaps = 70/600 (11%)
Query: 805 PNQDFHSKSPASSSLPAFLPTTHSPPGPQQPPASLPGLTAQPLLSPKEATSDPSRTPEEE 864
P + +K PA ++ PTT P P P +PKE +++
Sbjct: 292 PKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTT 351
Query: 865 PLNLEGLVAHRVAGVQAREKQP--AEPPAPLRRRAASDGQYENQSPEATSPRSPG---VR 919
P A +E P + PAP ++A E P T+P+ P +
Sbjct: 352 PKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKE---PAPTTPKKPAPTTPK 408
Query: 920 SPVQCVSPELALTIALNPGGRPKEPHLHSYKE----AFEEMEGTSPSSPPPSGVRSP-PG 974
P E T P KEP + KE A ++ T+P P P+ + P P
Sbjct: 409 EPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPT 468
Query: 975 LAKTPLSALGLKPHNPADILLHPTGVTRRRIQPEEDEGKVVVRLSEEPRSYVESVARTAV 1034
K P P PA T + P + P + E T
Sbjct: 469 TTKEPSPT---TPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPK 525
Query: 1035 AGPRAQDSEPKSFSAPATQAYGHEIPLRNGTLGGSFVSPSPLSTSSPILSADSTSVGSFP 1094
+P + + P T + +P + ++P +A +T P
Sbjct: 526 EPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTP 585
Query: 1095 SGESSDQGPRTPTQPLLESGFRSGSLGQPSPSAQRNYQSSSPLPTVGSSYSSPDYSLQHF 1154
+ P TP +P + L +P P PT + ++P+ +
Sbjct: 586 T-TPEKLAPTTPEKP---APTTPEELAPTTPEEPTPTTPEEPAPTTPKA-AAPNTPKEPA 640
Query: 1155 SSSPESQARAQFSVAGVHTVPGSPQARHRTVGTNTPPSPGFGWRAINPSMAAPSSPSLSH 1214
++P+ A P +P+ T T P+ G AP++P
Sbjct: 641 PTTPKEPA------------PTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPA 688
Query: 1215 HQMMGPPGTGFHGSTV------SSPQSSAATTPGSPSLCRHPAGVYQVSGLHNKVATTPG 1268
+ + P T ST ++P+ +A TTP P+ TTP
Sbjct: 689 PKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPA------------------PTTPK 730
Query: 1269 SPSLGRHPGAHQGNLASGLHSNAIASPGSPSLGRHLGGSGSVVPGSPCLDRHVAYGGYST 1328
P+ P +G + L A +P P+ + L + + P S D+ +T
Sbjct: 731 EPA----PTTPKGTAPTTLKEPAPTTPKKPA-PKELAPTTTKGPTSTTSDKPAP----TT 781
Query: 1329 PEDRRPTLSRQSSASGYQ--APSTPSFPVSPAYYPGLSSPATSPSPDSAAFRQGSPTPAL 1386
P++ PT ++ + + + AP+TP P P +S+P T+ P + TP L
Sbjct: 782 PKETAPTTPKEPAPTTPKKPAPTTPETP--PPTTSEVSTPTTTKEPTTIHKSPDESTPEL 839
Score = 67.0 bits (162), Expect = 2e-10
Identities = 164/821 (19%), Positives = 273/821 (33%), Gaps = 138/821 (16%)
Query: 660 PRPPPRQQERAHLESLVASRPS-PQPLAETPIPSLPEFPRAASQQEIEQSIETLNMLMLD 718
P+ P + + + S P+ P+ A T S P P+ + ++ T
Sbjct: 314 PKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPK---- 369
Query: 719 LEPASAAAPLHKSQSVPGAWPGASPLSSQPLSGSSRQSHPLTQSRSGYIPSGHSLGTP-E 777
EPA P + P A +P + ++ P T P + TP E
Sbjct: 370 -EPA----PTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTT-------PKEPAPTTPKE 417
Query: 778 PAPRASLESVPPGRSYSPYD-YQPCLAGPNQDFHS--KSPASSSLPAFLPTTHSPPGPQQ 834
P P E P + +P +P P + + K PA ++ PTT P P
Sbjct: 418 PTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTT 477
Query: 835 P--PA-----SLPGLTAQPL--------LSPKE----ATSDPSRTPEEEPLNLEGLVAHR 875
P PA S P T +P +PKE T +P+ T +EP +
Sbjct: 478 PKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEP---APTTPKK 534
Query: 876 VAGVQAREKQPAEPPAPLRRRAASDGQYENQSPEATSPRSPGVRSPVQC--VSPE-LALT 932
A +E P P P + P T+P+ +P + +PE LA T
Sbjct: 535 PAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPT 594
Query: 933 IALNPGGRPKEPHLHSYKEAFEEMEGTSPSSPPPSGVRSPPGLAKTPLSALGLKPHNPAD 992
P P P EE+ T+P P P+ P TP +A P PA
Sbjct: 595 TPEKPA--PTTP---------EELAPTTPEEPTPTTPEEP--APTTPKAAAPNTPKEPAP 641
Query: 993 IL---------LHPTGVTRRRIQPEEDEGKVVVRLSEEPRSYVESVARTAVAGPRAQDSE 1043
P T + P +G L E A T P ++
Sbjct: 642 TTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEP--------APTTPKKPAPKELA 693
Query: 1044 PKSFSAPATQAYGHEIPLR-NGTLGGSFVSPSPLSTSSPILSADSTSVGSFPSGESSDQG 1102
P + P + P GT + P+P + P A +T G+ P+ +
Sbjct: 694 PTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEP---APTTPKGTAPT-TLKEPA 749
Query: 1103 PRTPTQ-------PLLESGFRSGSLGQPSPSAQRNYQSSSPLPTVGSSYSSPDYSLQHFS 1155
P TP + P G S + +P+P+ + ++P ++ P
Sbjct: 750 PTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKP------AP 803
Query: 1156 SSPESQARAQFSVAGVHTVPGSPQARHRTVGTNTP-----PSPGFGWRAINPSMAAPSSP 1210
++PE+ V+ T P H++ +TP P+P +A+ S P P
Sbjct: 804 TTPETPPPTTSEVS-TPTTTKEPTTIHKSPDESTPELSAEPTP----KALENSPKEPGVP 858
Query: 1211 SLSHHQMMGP--PGTGFHGSTVSSPQSSAATTPGSPSLCRHPAGVYQVSGLHNKVATTPG 1268
+ P T +T +++ TT +P + + A + + ATT
Sbjct: 859 TTKTPAATKPEMTTTAKDKTTERDLRTTPETTTAAPKMTKETATTTEKTTESKITATTTQ 918
Query: 1269 SPSLGRHPGAHQGNLASGLHSNAIASPGSPSLGRHLGGSGSVVPGSPCLDR--------- 1319
S I + + +L + + + + +++
Sbjct: 919 VTS----------TTTQDTTPFKITTLKTTTLAPKVTTTKKTITTTEIMNKPEETAKPKD 968
Query: 1320 HVAYGGYSTPEDRRPTLSRQSSASGYQAPSTPSFPVSPAYYPGLSSPATSPSPD--SAAF 1377
+TP+ ++PT +AP P+ P P + P T+P+P ++
Sbjct: 969 RATNSKATTPKPQKPT----------KAPKKPTSTKKPKTMPRVRKPKTTPTPRKMTSTM 1018
Query: 1378 RQGSPTPALPEKRRMSVGDRAGSLPNYATINGKVSSPVASG 1418
+ +PT + E + R PN + S A G
Sbjct: 1019 PELNPTSRIAE-AMLQTTTRPNQTPNSKLVEVNPKSEDAGG 1058
Score = 40.4 bits (93), Expect = 0.015
Identities = 62/307 (20%), Positives = 105/307 (34%), Gaps = 23/307 (7%)
Query: 569 PAHAGHTAPMRPSYSAQEGLAGYQREGPHPAWP-QPVTTSHYAHDPSGMFRSQSFSEAEP 627
P T P +P+ + E LA E P P P +P T+ A P+ + EP
Sbjct: 588 PEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEP 647
Query: 628 ----QLPPAPVRGGSSREAVQRGLNSWQQQQQQQQQPRPPPRQQERAHLESLVASRPSPQ 683
PAP + +G ++ P+ P ++ S +
Sbjct: 648 APTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDK 707
Query: 684 PLAETP---IPSLPEFPRAASQQEIEQSIE--TLNMLMLDLEPASAAAPLHKSQSVPGAW 738
P TP P+ P+ P + +E + T + + P + P K +
Sbjct: 708 PAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTK 767
Query: 739 PGASPLSSQPLSGSSRQSHPLT-QSRSGYIPSGHSLGTPEPAPRASLESVPPGRSYSPYD 797
S S +P + +++ P T + + P + TPE P + E P + P
Sbjct: 768 GPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTT 827
Query: 798 YQPCLAGPNQDFHSKSPASSSLPAFLPTTHSPPGPQQPPASLPGLTAQPLLSPKEATSDP 857
P++ +P S+ P +SP P P P T P+ T+
Sbjct: 828 IH---KSPDE----STPELSAEPTPKALENSPKEPGVPTTKTPAAT-----KPEMTTTAK 875
Query: 858 SRTPEEE 864
+T E +
Sbjct: 876 DKTTERD 882
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.312 0.129 0.384
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 83,990,437
Number of Sequences: 37866
Number of extensions: 5085126
Number of successful extensions: 30097
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 153
Number of HSP's successfully gapped in prelim test: 1679
Number of HSP's that attempted gapping in prelim test: 19151
Number of HSP's gapped (non-prelim): 9145
length of query: 1735
length of database: 18,247,518
effective HSP length: 116
effective length of query: 1619
effective length of database: 13,855,062
effective search space: 22431345378
effective search space used: 22431345378
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 69 (31.2 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.