Guide to the Human Genome
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Search of human proteins with 6552299

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|6552299 breast cancer 1, early onset isoform 1 [Homo
sapiens]
         (1863 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|6552299 breast cancer 1, early onset isoform 1 [Homo sapiens]     3722   0.0  
gi|237681119 breast cancer 1, early onset isoform 2 [Homo sapiens]   3709   0.0  
gi|237681121 breast cancer 1, early onset isoform 3 [Homo sapiens]   3626   0.0  
gi|237681123 breast cancer 1, early onset isoform 4 [Homo sapiens]   1008   0.0  
gi|237681125 breast cancer 1, early onset isoform 5 [Homo sapiens]    828   0.0  
gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens]    73   2e-12
gi|62865604 tripartite motif protein 31 [Homo sapiens]                 65   8e-10
gi|21071052 helicase-like transcription factor [Homo sapiens]          59   4e-08
gi|21071054 helicase-like transcription factor [Homo sapiens]          59   4e-08
gi|117938316 tripartite motif-containing 22 [Homo sapiens]             58   1e-07
gi|14719418 tripartite motif protein TRIM5 isoform alpha [Homo s...    57   2e-07
gi|15011946 tripartite motif protein TRIM5 isoform delta [Homo s...    56   3e-07
gi|15011944 tripartite motif protein TRIM5 isoform gamma [Homo s...    56   3e-07
gi|30023818 tripartite motif protein 50A [Homo sapiens]                56   3e-07
gi|157266328 BRCA1 associated RING domain 1 [Homo sapiens]             55   8e-07
gi|145275183 tripartite motif protein 34 isoform 3 [Homo sapiens]      54   1e-06
gi|51477687 tripartite motif protein 34 isoform 1 [Homo sapiens]       54   1e-06
gi|18087807 tripartite motif protein 34 isoform 1 [Homo sapiens]       54   1e-06
gi|14670266 tripartite motif protein TRIM4 isoform alpha [Homo s...    54   1e-06
gi|15011941 tripartite motif protein TRIM4 isoform beta [Homo sa...    54   1e-06
gi|51477690 tripartite motif-containing 6 and tripartite motif-c...    54   1e-06
gi|21630277 tripartite motif-containing 11 [Homo sapiens]              54   1e-06
gi|15208660 tripartite motif protein 21 [Homo sapiens]                 54   1e-06
gi|25777698 tripartite motif-containing 39 isoform 2 [Homo sapiens]    54   1e-06
gi|25777696 tripartite motif-containing 39 isoform 1 [Homo sapiens]    54   1e-06
gi|4508005 tripartite motif-containing 26 [Homo sapiens]               54   1e-06
gi|6005747 ring finger protein 2 [Homo sapiens]                        54   2e-06
gi|87080813 LON peptidase N-terminal domain and ring finger 1 [H...    54   2e-06
gi|18079262 tripartite motif-containing 6 isoform 2 [Homo sapiens]     53   3e-06
gi|51477692 tripartite motif-containing 6 isoform 1 [Homo sapiens]     53   3e-06

>gi|6552299 breast cancer 1, early onset isoform 1 [Homo sapiens]
          Length = 1863

 Score = 3722 bits (9652), Expect = 0.0
 Identities = 1863/1863 (100%), Positives = 1863/1863 (100%)

Query: 1    MDLSALRVEEVQNVINAMQKILECPICLELIKEPVSTKCDHIFCKFCMLKLLNQKKGPSQ 60
            MDLSALRVEEVQNVINAMQKILECPICLELIKEPVSTKCDHIFCKFCMLKLLNQKKGPSQ
Sbjct: 1    MDLSALRVEEVQNVINAMQKILECPICLELIKEPVSTKCDHIFCKFCMLKLLNQKKGPSQ 60

Query: 61   CPLCKNDITKRSLQESTRFSQLVEELLKIICAFQLDTGLEYANSYNFAKKENNSPEHLKD 120
            CPLCKNDITKRSLQESTRFSQLVEELLKIICAFQLDTGLEYANSYNFAKKENNSPEHLKD
Sbjct: 61   CPLCKNDITKRSLQESTRFSQLVEELLKIICAFQLDTGLEYANSYNFAKKENNSPEHLKD 120

Query: 121  EVSIIQSMGYRNRAKRLLQSEPENPSLQETSLSVQLSNLGTVRTLRTKQRIQPQKTSVYI 180
            EVSIIQSMGYRNRAKRLLQSEPENPSLQETSLSVQLSNLGTVRTLRTKQRIQPQKTSVYI
Sbjct: 121  EVSIIQSMGYRNRAKRLLQSEPENPSLQETSLSVQLSNLGTVRTLRTKQRIQPQKTSVYI 180

Query: 181  ELGSDSSEDTVNKATYCSVGDQELLQITPQGTRDEISLDSAKKAACEFSETDVTNTEHHQ 240
            ELGSDSSEDTVNKATYCSVGDQELLQITPQGTRDEISLDSAKKAACEFSETDVTNTEHHQ
Sbjct: 181  ELGSDSSEDTVNKATYCSVGDQELLQITPQGTRDEISLDSAKKAACEFSETDVTNTEHHQ 240

Query: 241  PSNNDLNTTEKRAAERHPEKYQGSSVSNLHVEPCGTNTHASSLQHENSSLLLTKDRMNVE 300
            PSNNDLNTTEKRAAERHPEKYQGSSVSNLHVEPCGTNTHASSLQHENSSLLLTKDRMNVE
Sbjct: 241  PSNNDLNTTEKRAAERHPEKYQGSSVSNLHVEPCGTNTHASSLQHENSSLLLTKDRMNVE 300

Query: 301  KAEFCNKSKQPGLARSQHNRWAGSKETCNDRRTPSTEKKVDLNADPLCERKEWNKQKLPC 360
            KAEFCNKSKQPGLARSQHNRWAGSKETCNDRRTPSTEKKVDLNADPLCERKEWNKQKLPC
Sbjct: 301  KAEFCNKSKQPGLARSQHNRWAGSKETCNDRRTPSTEKKVDLNADPLCERKEWNKQKLPC 360

Query: 361  SENPRDTEDVPWITLNSSIQKVNEWFSRSDELLGSDDSHDGESESNAKVADVLDVLNEVD 420
            SENPRDTEDVPWITLNSSIQKVNEWFSRSDELLGSDDSHDGESESNAKVADVLDVLNEVD
Sbjct: 361  SENPRDTEDVPWITLNSSIQKVNEWFSRSDELLGSDDSHDGESESNAKVADVLDVLNEVD 420

Query: 421  EYSGSSEKIDLLASDPHEALICKSERVHSKSVESNIEDKIFGKTYRKKASLPNLSHVTEN 480
            EYSGSSEKIDLLASDPHEALICKSERVHSKSVESNIEDKIFGKTYRKKASLPNLSHVTEN
Sbjct: 421  EYSGSSEKIDLLASDPHEALICKSERVHSKSVESNIEDKIFGKTYRKKASLPNLSHVTEN 480

Query: 481  LIIGAFVTEPQIIQERPLTNKLKRKRRPTSGLHPEDFIKKADLAVQKTPEMINQGTNQTE 540
            LIIGAFVTEPQIIQERPLTNKLKRKRRPTSGLHPEDFIKKADLAVQKTPEMINQGTNQTE
Sbjct: 481  LIIGAFVTEPQIIQERPLTNKLKRKRRPTSGLHPEDFIKKADLAVQKTPEMINQGTNQTE 540

Query: 541  QNGQVMNITNSGHENKTKGDSIQNEKNPNPIESLEKESAFKTKAEPISSSISNMELELNI 600
            QNGQVMNITNSGHENKTKGDSIQNEKNPNPIESLEKESAFKTKAEPISSSISNMELELNI
Sbjct: 541  QNGQVMNITNSGHENKTKGDSIQNEKNPNPIESLEKESAFKTKAEPISSSISNMELELNI 600

Query: 601  HNSKAPKKNRLRRKSSTRHIHALELVVSRNLSPPNCTELQIDSCSSSEEIKKKKYNQMPV 660
            HNSKAPKKNRLRRKSSTRHIHALELVVSRNLSPPNCTELQIDSCSSSEEIKKKKYNQMPV
Sbjct: 601  HNSKAPKKNRLRRKSSTRHIHALELVVSRNLSPPNCTELQIDSCSSSEEIKKKKYNQMPV 660

Query: 661  RHSRNLQLMEGKEPATGAKKSNKPNEQTSKRHDSDTFPELKLTNAPGSFTKCSNTSELKE 720
            RHSRNLQLMEGKEPATGAKKSNKPNEQTSKRHDSDTFPELKLTNAPGSFTKCSNTSELKE
Sbjct: 661  RHSRNLQLMEGKEPATGAKKSNKPNEQTSKRHDSDTFPELKLTNAPGSFTKCSNTSELKE 720

Query: 721  FVNPSLPREEKEEKLETVKVSNNAEDPKDLMLSGERVLQTERSVESSSISLVPGTDYGTQ 780
            FVNPSLPREEKEEKLETVKVSNNAEDPKDLMLSGERVLQTERSVESSSISLVPGTDYGTQ
Sbjct: 721  FVNPSLPREEKEEKLETVKVSNNAEDPKDLMLSGERVLQTERSVESSSISLVPGTDYGTQ 780

Query: 781  ESISLLEVSTLGKAKTEPNKCVSQCAAFENPKGLIHGCSKDNRNDTEGFKYPLGHEVNHS 840
            ESISLLEVSTLGKAKTEPNKCVSQCAAFENPKGLIHGCSKDNRNDTEGFKYPLGHEVNHS
Sbjct: 781  ESISLLEVSTLGKAKTEPNKCVSQCAAFENPKGLIHGCSKDNRNDTEGFKYPLGHEVNHS 840

Query: 841  RETSIEMEESELDAQYLQNTFKVSKRQSFAPFSNPGNAEEECATFSAHSGSLKKQSPKVT 900
            RETSIEMEESELDAQYLQNTFKVSKRQSFAPFSNPGNAEEECATFSAHSGSLKKQSPKVT
Sbjct: 841  RETSIEMEESELDAQYLQNTFKVSKRQSFAPFSNPGNAEEECATFSAHSGSLKKQSPKVT 900

Query: 901  FECEQKEENQGKNESNIKPVQTVNITAGFPVVGQKDKPVDNAKCSIKGGSRFCLSSQFRG 960
            FECEQKEENQGKNESNIKPVQTVNITAGFPVVGQKDKPVDNAKCSIKGGSRFCLSSQFRG
Sbjct: 901  FECEQKEENQGKNESNIKPVQTVNITAGFPVVGQKDKPVDNAKCSIKGGSRFCLSSQFRG 960

Query: 961  NETGLITPNKHGLLQNPYRIPPLFPIKSFVKTKCKKNLLEENFEEHSMSPEREMGNENIP 1020
            NETGLITPNKHGLLQNPYRIPPLFPIKSFVKTKCKKNLLEENFEEHSMSPEREMGNENIP
Sbjct: 961  NETGLITPNKHGLLQNPYRIPPLFPIKSFVKTKCKKNLLEENFEEHSMSPEREMGNENIP 1020

Query: 1021 STVSTISRNNIRENVFKEASSSNINEVGSSTNEVGSSINEIGSSDENIQAELGRNRGPKL 1080
            STVSTISRNNIRENVFKEASSSNINEVGSSTNEVGSSINEIGSSDENIQAELGRNRGPKL
Sbjct: 1021 STVSTISRNNIRENVFKEASSSNINEVGSSTNEVGSSINEIGSSDENIQAELGRNRGPKL 1080

Query: 1081 NAMLRLGVLQPEVYKQSLPGSNCKHPEIKKQEYEEVVQTVNTDFSPYLISDNLEQPMGSS 1140
            NAMLRLGVLQPEVYKQSLPGSNCKHPEIKKQEYEEVVQTVNTDFSPYLISDNLEQPMGSS
Sbjct: 1081 NAMLRLGVLQPEVYKQSLPGSNCKHPEIKKQEYEEVVQTVNTDFSPYLISDNLEQPMGSS 1140

Query: 1141 HASQVCSETPDDLLDDGEIKEDTSFAENDIKESSAVFSKSVQKGELSRSPSPFTHTHLAQ 1200
            HASQVCSETPDDLLDDGEIKEDTSFAENDIKESSAVFSKSVQKGELSRSPSPFTHTHLAQ
Sbjct: 1141 HASQVCSETPDDLLDDGEIKEDTSFAENDIKESSAVFSKSVQKGELSRSPSPFTHTHLAQ 1200

Query: 1201 GYRRGAKKLESSEENLSSEDEELPCFQHLLFGKVNNIPSQSTRHSTVATECLSKNTEENL 1260
            GYRRGAKKLESSEENLSSEDEELPCFQHLLFGKVNNIPSQSTRHSTVATECLSKNTEENL
Sbjct: 1201 GYRRGAKKLESSEENLSSEDEELPCFQHLLFGKVNNIPSQSTRHSTVATECLSKNTEENL 1260

Query: 1261 LSLKNSLNDCSNQVILAKASQEHHLSEETKCSASLFSSQCSELEDLTANTNTQDPFLIGS 1320
            LSLKNSLNDCSNQVILAKASQEHHLSEETKCSASLFSSQCSELEDLTANTNTQDPFLIGS
Sbjct: 1261 LSLKNSLNDCSNQVILAKASQEHHLSEETKCSASLFSSQCSELEDLTANTNTQDPFLIGS 1320

Query: 1321 SKQMRHQSESQGVGLSDKELVSDDEERGTGLEENNQEEQSMDSNLGEAASGCESETSVSE 1380
            SKQMRHQSESQGVGLSDKELVSDDEERGTGLEENNQEEQSMDSNLGEAASGCESETSVSE
Sbjct: 1321 SKQMRHQSESQGVGLSDKELVSDDEERGTGLEENNQEEQSMDSNLGEAASGCESETSVSE 1380

Query: 1381 DCSGLSSQSDILTTQQRDTMQHNLIKLQQEMAELEAVLEQHGSQPSNSYPSIISDSSALE 1440
            DCSGLSSQSDILTTQQRDTMQHNLIKLQQEMAELEAVLEQHGSQPSNSYPSIISDSSALE
Sbjct: 1381 DCSGLSSQSDILTTQQRDTMQHNLIKLQQEMAELEAVLEQHGSQPSNSYPSIISDSSALE 1440

Query: 1441 DLRNPEQSTSEKAVLTSQKSSEYPISQNPEGLSADKFEVSADSSTSKNKEPGVERSSPSK 1500
            DLRNPEQSTSEKAVLTSQKSSEYPISQNPEGLSADKFEVSADSSTSKNKEPGVERSSPSK
Sbjct: 1441 DLRNPEQSTSEKAVLTSQKSSEYPISQNPEGLSADKFEVSADSSTSKNKEPGVERSSPSK 1500

Query: 1501 CPSLDDRWYMHSCSGSLQNRNYPSQEELIKVVDVEEQQLEESGPHDLTETSYLPRQDLEG 1560
            CPSLDDRWYMHSCSGSLQNRNYPSQEELIKVVDVEEQQLEESGPHDLTETSYLPRQDLEG
Sbjct: 1501 CPSLDDRWYMHSCSGSLQNRNYPSQEELIKVVDVEEQQLEESGPHDLTETSYLPRQDLEG 1560

Query: 1561 TPYLESGISLFSDDPESDPSEDRAPESARVGNIPSSTSALKVPQLKVAESAQSPAAAHTT 1620
            TPYLESGISLFSDDPESDPSEDRAPESARVGNIPSSTSALKVPQLKVAESAQSPAAAHTT
Sbjct: 1561 TPYLESGISLFSDDPESDPSEDRAPESARVGNIPSSTSALKVPQLKVAESAQSPAAAHTT 1620

Query: 1621 DTAGYNAMEESVSREKPELTASTERVNKRMSMVVSGLTPEEFMLVYKFARKHHITLTNLI 1680
            DTAGYNAMEESVSREKPELTASTERVNKRMSMVVSGLTPEEFMLVYKFARKHHITLTNLI
Sbjct: 1621 DTAGYNAMEESVSREKPELTASTERVNKRMSMVVSGLTPEEFMLVYKFARKHHITLTNLI 1680

Query: 1681 TEETTHVVMKTDAEFVCERTLKYFLGIAGGKWVVSYFWVTQSIKERKMLNEHDFEVRGDV 1740
            TEETTHVVMKTDAEFVCERTLKYFLGIAGGKWVVSYFWVTQSIKERKMLNEHDFEVRGDV
Sbjct: 1681 TEETTHVVMKTDAEFVCERTLKYFLGIAGGKWVVSYFWVTQSIKERKMLNEHDFEVRGDV 1740

Query: 1741 VNGRNHQGPKRARESQDRKIFRGLEICCYGPFTNMPTDQLEWMVQLCGASVVKELSSFTL 1800
            VNGRNHQGPKRARESQDRKIFRGLEICCYGPFTNMPTDQLEWMVQLCGASVVKELSSFTL
Sbjct: 1741 VNGRNHQGPKRARESQDRKIFRGLEICCYGPFTNMPTDQLEWMVQLCGASVVKELSSFTL 1800

Query: 1801 GTGVHPIVVVQPDAWTEDNGFHAIGQMCEAPVVTREWVLDSVALYQCQELDTYLIPQIPH 1860
            GTGVHPIVVVQPDAWTEDNGFHAIGQMCEAPVVTREWVLDSVALYQCQELDTYLIPQIPH
Sbjct: 1801 GTGVHPIVVVQPDAWTEDNGFHAIGQMCEAPVVTREWVLDSVALYQCQELDTYLIPQIPH 1860

Query: 1861 SHY 1863
            SHY
Sbjct: 1861 SHY 1863


>gi|237681119 breast cancer 1, early onset isoform 2 [Homo sapiens]
          Length = 1884

 Score = 3709 bits (9617), Expect = 0.0
 Identities = 1862/1884 (98%), Positives = 1863/1884 (98%), Gaps = 21/1884 (1%)

Query: 1    MDLSALRVEEVQNVINAMQKILECPICLELIKEPVSTKCDHIFCKFCMLKLLNQKKGPSQ 60
            MDLSALRVEEVQNVINAMQKILECPICLELIKEPVSTKCDHIFCKFCMLKLLNQKKGPSQ
Sbjct: 1    MDLSALRVEEVQNVINAMQKILECPICLELIKEPVSTKCDHIFCKFCMLKLLNQKKGPSQ 60

Query: 61   CPLCKNDITKRSLQESTRFSQLVEELLKIICAFQLDTGLEYANSYNFAKKENNSPEHLKD 120
            CPLCKNDITKRSLQESTRFSQLVEELLKIICAFQLDTGLEYANSYNFAKKENNSPEHLKD
Sbjct: 61   CPLCKNDITKRSLQESTRFSQLVEELLKIICAFQLDTGLEYANSYNFAKKENNSPEHLKD 120

Query: 121  EVSIIQSMGYRNRAKRLLQSEPENPSLQETSLSVQLSNLGTVRTLRTKQRIQPQKTSVYI 180
            EVSIIQSMGYRNRAKRLLQSEPENPSLQETSLSVQLSNLGTVRTLRTKQRIQPQKTSVYI
Sbjct: 121  EVSIIQSMGYRNRAKRLLQSEPENPSLQETSLSVQLSNLGTVRTLRTKQRIQPQKTSVYI 180

Query: 181  ELGSDSSEDTVNKATYCSVGDQELLQITPQGTRDEISLDSAKKAACEFSETDVTNTEHHQ 240
            ELGSDSSEDTVNKATYCSVGDQELLQITPQGTRDEISLDSAKKAACEFSETDVTNTEHHQ
Sbjct: 181  ELGSDSSEDTVNKATYCSVGDQELLQITPQGTRDEISLDSAKKAACEFSETDVTNTEHHQ 240

Query: 241  PSNNDLNTTEKRAAERHPEKYQGSSVSNLHVEPCGTNTHASSLQHENSSLLLTKDRMNVE 300
            PSNNDLNTTEKRAAERHPEKYQGSSVSNLHVEPCGTNTHASSLQHENSSLLLTKDRMNVE
Sbjct: 241  PSNNDLNTTEKRAAERHPEKYQGSSVSNLHVEPCGTNTHASSLQHENSSLLLTKDRMNVE 300

Query: 301  KAEFCNKSKQPGLARSQHNRWAGSKETCNDRRTPSTEKKVDLNADPLCERKEWNKQKLPC 360
            KAEFCNKSKQPGLARSQHNRWAGSKETCNDRRTPSTEKKVDLNADPLCERKEWNKQKLPC
Sbjct: 301  KAEFCNKSKQPGLARSQHNRWAGSKETCNDRRTPSTEKKVDLNADPLCERKEWNKQKLPC 360

Query: 361  SENPRDTEDVPWITLNSSIQKVNEWFSRSDELLGSDDSHDGESESNAKVADVLDVLNEVD 420
            SENPRDTEDVPWITLNSSIQKVNEWFSRSDELLGSDDSHDGESESNAKVADVLDVLNEVD
Sbjct: 361  SENPRDTEDVPWITLNSSIQKVNEWFSRSDELLGSDDSHDGESESNAKVADVLDVLNEVD 420

Query: 421  EYSGSSEKIDLLASDPHEALICKSERVHSKSVESNIEDKIFGKTYRKKASLPNLSHVTEN 480
            EYSGSSEKIDLLASDPHEALICKSERVHSKSVESNIEDKIFGKTYRKKASLPNLSHVTEN
Sbjct: 421  EYSGSSEKIDLLASDPHEALICKSERVHSKSVESNIEDKIFGKTYRKKASLPNLSHVTEN 480

Query: 481  LIIGAFVTEPQIIQERPLTNKLKRKRRPTSGLHPEDFIKKADLAVQKTPEMINQGTNQTE 540
            LIIGAFVTEPQIIQERPLTNKLKRKRRPTSGLHPEDFIKKADLAVQKTPEMINQGTNQTE
Sbjct: 481  LIIGAFVTEPQIIQERPLTNKLKRKRRPTSGLHPEDFIKKADLAVQKTPEMINQGTNQTE 540

Query: 541  QNGQVMNITNSGHENKTKGDSIQNEKNPNPIESLEKESAFKTKAEPISSSISNMELELNI 600
            QNGQVMNITNSGHENKTKGDSIQNEKNPNPIESLEKESAFKTKAEPISSSISNMELELNI
Sbjct: 541  QNGQVMNITNSGHENKTKGDSIQNEKNPNPIESLEKESAFKTKAEPISSSISNMELELNI 600

Query: 601  HNSKAPKKNRLRRKSSTRHIHALELVVSRNLSPPNCTELQIDSCSSSEEIKKKKYNQMPV 660
            HNSKAPKKNRLRRKSSTRHIHALELVVSRNLSPPNCTELQIDSCSSSEEIKKKKYNQMPV
Sbjct: 601  HNSKAPKKNRLRRKSSTRHIHALELVVSRNLSPPNCTELQIDSCSSSEEIKKKKYNQMPV 660

Query: 661  RHSRNLQLMEGKEPATGAKKSNKPNEQTSKRHDSDTFPELKLTNAPGSFTKCSNTSELKE 720
            RHSRNLQLMEGKEPATGAKKSNKPNEQTSKRHDSDTFPELKLTNAPGSFTKCSNTSELKE
Sbjct: 661  RHSRNLQLMEGKEPATGAKKSNKPNEQTSKRHDSDTFPELKLTNAPGSFTKCSNTSELKE 720

Query: 721  FVNPSLPREEKEEKLETVKVSNNAEDPKDLMLSGERVLQTERSVESSSISLVPGTDYGTQ 780
            FVNPSLPREEKEEKLETVKVSNNAEDPKDLMLSGERVLQTERSVESSSISLVPGTDYGTQ
Sbjct: 721  FVNPSLPREEKEEKLETVKVSNNAEDPKDLMLSGERVLQTERSVESSSISLVPGTDYGTQ 780

Query: 781  ESISLLEVSTLGKAKTEPNKCVSQCAAFENPKGLIHGCSKDNRNDTEGFKYPLGHEVNHS 840
            ESISLLEVSTLGKAKTEPNKCVSQCAAFENPKGLIHGCSKDNRNDTEGFKYPLGHEVNHS
Sbjct: 781  ESISLLEVSTLGKAKTEPNKCVSQCAAFENPKGLIHGCSKDNRNDTEGFKYPLGHEVNHS 840

Query: 841  RETSIEMEESELDAQYLQNTFKVSKRQSFAPFSNPGNAEEECATFSAHSGSLKKQSPKVT 900
            RETSIEMEESELDAQYLQNTFKVSKRQSFAPFSNPGNAEEECATFSAHSGSLKKQSPKVT
Sbjct: 841  RETSIEMEESELDAQYLQNTFKVSKRQSFAPFSNPGNAEEECATFSAHSGSLKKQSPKVT 900

Query: 901  FECEQKEENQGKNESNIKPVQTVNITAGFPVVGQKDKPVDNAKCSIKGGSRFCLSSQFRG 960
            FECEQKEENQGKNESNIKPVQTVNITAGFPVVGQKDKPVDNAKCSIKGGSRFCLSSQFRG
Sbjct: 901  FECEQKEENQGKNESNIKPVQTVNITAGFPVVGQKDKPVDNAKCSIKGGSRFCLSSQFRG 960

Query: 961  NETGLITPNKHGLLQNPYRIPPLFPIKSFVKTKCKKNLLEENFEEHSMSPEREMGNENIP 1020
            NETGLITPNKHGLLQNPYRIPPLFPIKSFVKTKCKKNLLEENFEEHSMSPEREMGNENIP
Sbjct: 961  NETGLITPNKHGLLQNPYRIPPLFPIKSFVKTKCKKNLLEENFEEHSMSPEREMGNENIP 1020

Query: 1021 STVSTISRNNIRENVFKEASSSNINEVGSSTNEVGSSINEIGSSDENIQAELGRNRGPKL 1080
            STVSTISRNNIRENVFKEASSSNINEVGSSTNEVGSSINEIGSSDENIQAELGRNRGPKL
Sbjct: 1021 STVSTISRNNIRENVFKEASSSNINEVGSSTNEVGSSINEIGSSDENIQAELGRNRGPKL 1080

Query: 1081 NAMLRLGVLQPEVYKQSLPGSNCKHPEIKKQEYEEVVQTVNTDFSPYLISDNLEQPMGSS 1140
            NAMLRLGVLQPEVYKQSLPGSNCKHPEIKKQEYEEVVQTVNTDFSPYLISDNLEQPMGSS
Sbjct: 1081 NAMLRLGVLQPEVYKQSLPGSNCKHPEIKKQEYEEVVQTVNTDFSPYLISDNLEQPMGSS 1140

Query: 1141 HASQVCSETPDDLLDDGEIKEDTSFAENDIKESSAVFSKSVQKGELSRSPSPFTHTHLAQ 1200
            HASQVCSETPDDLLDDGEIKEDTSFAENDIKESSAVFSKSVQKGELSRSPSPFTHTHLAQ
Sbjct: 1141 HASQVCSETPDDLLDDGEIKEDTSFAENDIKESSAVFSKSVQKGELSRSPSPFTHTHLAQ 1200

Query: 1201 GYRRGAKKLESSEENLSSEDEELPCFQHLLFGKVNNIPSQSTRHSTVATECLSKNTEENL 1260
            GYRRGAKKLESSEENLSSEDEELPCFQHLLFGKVNNIPSQSTRHSTVATECLSKNTEENL
Sbjct: 1201 GYRRGAKKLESSEENLSSEDEELPCFQHLLFGKVNNIPSQSTRHSTVATECLSKNTEENL 1260

Query: 1261 LSLKNSLNDCSNQVILAKASQEHHLSEETKCSASLFSSQCSELEDLTANTNTQDPFLIGS 1320
            LSLKNSLNDCSNQVILAKASQEHHLSEETKCSASLFSSQCSELEDLTANTNTQDPFLIGS
Sbjct: 1261 LSLKNSLNDCSNQVILAKASQEHHLSEETKCSASLFSSQCSELEDLTANTNTQDPFLIGS 1320

Query: 1321 SKQMRHQSESQGVGLSDKELVSDDEERGTGLEENNQEEQSMDSNLGEAASGCESETSVSE 1380
            SKQMRHQSESQGVGLSDKELVSDDEERGTGLEENNQEEQSMDSNLGEAASGCESETSVSE
Sbjct: 1321 SKQMRHQSESQGVGLSDKELVSDDEERGTGLEENNQEEQSMDSNLGEAASGCESETSVSE 1380

Query: 1381 DCSGLSSQSDILTTQQRDTMQHNLIKLQQEMAELEAVLEQHGSQPSNSYPSIISDSSALE 1440
            DCSGLSSQSDILTTQQRDTMQHNLIKLQQEMAELEAVLEQHGSQPSNSYPSIISDSSALE
Sbjct: 1381 DCSGLSSQSDILTTQQRDTMQHNLIKLQQEMAELEAVLEQHGSQPSNSYPSIISDSSALE 1440

Query: 1441 DLRNPEQSTSEK---------------------AVLTSQKSSEYPISQNPEGLSADKFEV 1479
            DLRNPEQSTSEK                     +VLTSQKSSEYPISQNPEGLSADKFEV
Sbjct: 1441 DLRNPEQSTSEKDSHIHGQRNNSMFSKRPREHISVLTSQKSSEYPISQNPEGLSADKFEV 1500

Query: 1480 SADSSTSKNKEPGVERSSPSKCPSLDDRWYMHSCSGSLQNRNYPSQEELIKVVDVEEQQL 1539
            SADSSTSKNKEPGVERSSPSKCPSLDDRWYMHSCSGSLQNRNYPSQEELIKVVDVEEQQL
Sbjct: 1501 SADSSTSKNKEPGVERSSPSKCPSLDDRWYMHSCSGSLQNRNYPSQEELIKVVDVEEQQL 1560

Query: 1540 EESGPHDLTETSYLPRQDLEGTPYLESGISLFSDDPESDPSEDRAPESARVGNIPSSTSA 1599
            EESGPHDLTETSYLPRQDLEGTPYLESGISLFSDDPESDPSEDRAPESARVGNIPSSTSA
Sbjct: 1561 EESGPHDLTETSYLPRQDLEGTPYLESGISLFSDDPESDPSEDRAPESARVGNIPSSTSA 1620

Query: 1600 LKVPQLKVAESAQSPAAAHTTDTAGYNAMEESVSREKPELTASTERVNKRMSMVVSGLTP 1659
            LKVPQLKVAESAQSPAAAHTTDTAGYNAMEESVSREKPELTASTERVNKRMSMVVSGLTP
Sbjct: 1621 LKVPQLKVAESAQSPAAAHTTDTAGYNAMEESVSREKPELTASTERVNKRMSMVVSGLTP 1680

Query: 1660 EEFMLVYKFARKHHITLTNLITEETTHVVMKTDAEFVCERTLKYFLGIAGGKWVVSYFWV 1719
            EEFMLVYKFARKHHITLTNLITEETTHVVMKTDAEFVCERTLKYFLGIAGGKWVVSYFWV
Sbjct: 1681 EEFMLVYKFARKHHITLTNLITEETTHVVMKTDAEFVCERTLKYFLGIAGGKWVVSYFWV 1740

Query: 1720 TQSIKERKMLNEHDFEVRGDVVNGRNHQGPKRARESQDRKIFRGLEICCYGPFTNMPTDQ 1779
            TQSIKERKMLNEHDFEVRGDVVNGRNHQGPKRARESQDRKIFRGLEICCYGPFTNMPTDQ
Sbjct: 1741 TQSIKERKMLNEHDFEVRGDVVNGRNHQGPKRARESQDRKIFRGLEICCYGPFTNMPTDQ 1800

Query: 1780 LEWMVQLCGASVVKELSSFTLGTGVHPIVVVQPDAWTEDNGFHAIGQMCEAPVVTREWVL 1839
            LEWMVQLCGASVVKELSSFTLGTGVHPIVVVQPDAWTEDNGFHAIGQMCEAPVVTREWVL
Sbjct: 1801 LEWMVQLCGASVVKELSSFTLGTGVHPIVVVQPDAWTEDNGFHAIGQMCEAPVVTREWVL 1860

Query: 1840 DSVALYQCQELDTYLIPQIPHSHY 1863
            DSVALYQCQELDTYLIPQIPHSHY
Sbjct: 1861 DSVALYQCQELDTYLIPQIPHSHY 1884


>gi|237681121 breast cancer 1, early onset isoform 3 [Homo sapiens]
          Length = 1816

 Score = 3626 bits (9402), Expect = 0.0
 Identities = 1816/1816 (100%), Positives = 1816/1816 (100%)

Query: 48   MLKLLNQKKGPSQCPLCKNDITKRSLQESTRFSQLVEELLKIICAFQLDTGLEYANSYNF 107
            MLKLLNQKKGPSQCPLCKNDITKRSLQESTRFSQLVEELLKIICAFQLDTGLEYANSYNF
Sbjct: 1    MLKLLNQKKGPSQCPLCKNDITKRSLQESTRFSQLVEELLKIICAFQLDTGLEYANSYNF 60

Query: 108  AKKENNSPEHLKDEVSIIQSMGYRNRAKRLLQSEPENPSLQETSLSVQLSNLGTVRTLRT 167
            AKKENNSPEHLKDEVSIIQSMGYRNRAKRLLQSEPENPSLQETSLSVQLSNLGTVRTLRT
Sbjct: 61   AKKENNSPEHLKDEVSIIQSMGYRNRAKRLLQSEPENPSLQETSLSVQLSNLGTVRTLRT 120

Query: 168  KQRIQPQKTSVYIELGSDSSEDTVNKATYCSVGDQELLQITPQGTRDEISLDSAKKAACE 227
            KQRIQPQKTSVYIELGSDSSEDTVNKATYCSVGDQELLQITPQGTRDEISLDSAKKAACE
Sbjct: 121  KQRIQPQKTSVYIELGSDSSEDTVNKATYCSVGDQELLQITPQGTRDEISLDSAKKAACE 180

Query: 228  FSETDVTNTEHHQPSNNDLNTTEKRAAERHPEKYQGSSVSNLHVEPCGTNTHASSLQHEN 287
            FSETDVTNTEHHQPSNNDLNTTEKRAAERHPEKYQGSSVSNLHVEPCGTNTHASSLQHEN
Sbjct: 181  FSETDVTNTEHHQPSNNDLNTTEKRAAERHPEKYQGSSVSNLHVEPCGTNTHASSLQHEN 240

Query: 288  SSLLLTKDRMNVEKAEFCNKSKQPGLARSQHNRWAGSKETCNDRRTPSTEKKVDLNADPL 347
            SSLLLTKDRMNVEKAEFCNKSKQPGLARSQHNRWAGSKETCNDRRTPSTEKKVDLNADPL
Sbjct: 241  SSLLLTKDRMNVEKAEFCNKSKQPGLARSQHNRWAGSKETCNDRRTPSTEKKVDLNADPL 300

Query: 348  CERKEWNKQKLPCSENPRDTEDVPWITLNSSIQKVNEWFSRSDELLGSDDSHDGESESNA 407
            CERKEWNKQKLPCSENPRDTEDVPWITLNSSIQKVNEWFSRSDELLGSDDSHDGESESNA
Sbjct: 301  CERKEWNKQKLPCSENPRDTEDVPWITLNSSIQKVNEWFSRSDELLGSDDSHDGESESNA 360

Query: 408  KVADVLDVLNEVDEYSGSSEKIDLLASDPHEALICKSERVHSKSVESNIEDKIFGKTYRK 467
            KVADVLDVLNEVDEYSGSSEKIDLLASDPHEALICKSERVHSKSVESNIEDKIFGKTYRK
Sbjct: 361  KVADVLDVLNEVDEYSGSSEKIDLLASDPHEALICKSERVHSKSVESNIEDKIFGKTYRK 420

Query: 468  KASLPNLSHVTENLIIGAFVTEPQIIQERPLTNKLKRKRRPTSGLHPEDFIKKADLAVQK 527
            KASLPNLSHVTENLIIGAFVTEPQIIQERPLTNKLKRKRRPTSGLHPEDFIKKADLAVQK
Sbjct: 421  KASLPNLSHVTENLIIGAFVTEPQIIQERPLTNKLKRKRRPTSGLHPEDFIKKADLAVQK 480

Query: 528  TPEMINQGTNQTEQNGQVMNITNSGHENKTKGDSIQNEKNPNPIESLEKESAFKTKAEPI 587
            TPEMINQGTNQTEQNGQVMNITNSGHENKTKGDSIQNEKNPNPIESLEKESAFKTKAEPI
Sbjct: 481  TPEMINQGTNQTEQNGQVMNITNSGHENKTKGDSIQNEKNPNPIESLEKESAFKTKAEPI 540

Query: 588  SSSISNMELELNIHNSKAPKKNRLRRKSSTRHIHALELVVSRNLSPPNCTELQIDSCSSS 647
            SSSISNMELELNIHNSKAPKKNRLRRKSSTRHIHALELVVSRNLSPPNCTELQIDSCSSS
Sbjct: 541  SSSISNMELELNIHNSKAPKKNRLRRKSSTRHIHALELVVSRNLSPPNCTELQIDSCSSS 600

Query: 648  EEIKKKKYNQMPVRHSRNLQLMEGKEPATGAKKSNKPNEQTSKRHDSDTFPELKLTNAPG 707
            EEIKKKKYNQMPVRHSRNLQLMEGKEPATGAKKSNKPNEQTSKRHDSDTFPELKLTNAPG
Sbjct: 601  EEIKKKKYNQMPVRHSRNLQLMEGKEPATGAKKSNKPNEQTSKRHDSDTFPELKLTNAPG 660

Query: 708  SFTKCSNTSELKEFVNPSLPREEKEEKLETVKVSNNAEDPKDLMLSGERVLQTERSVESS 767
            SFTKCSNTSELKEFVNPSLPREEKEEKLETVKVSNNAEDPKDLMLSGERVLQTERSVESS
Sbjct: 661  SFTKCSNTSELKEFVNPSLPREEKEEKLETVKVSNNAEDPKDLMLSGERVLQTERSVESS 720

Query: 768  SISLVPGTDYGTQESISLLEVSTLGKAKTEPNKCVSQCAAFENPKGLIHGCSKDNRNDTE 827
            SISLVPGTDYGTQESISLLEVSTLGKAKTEPNKCVSQCAAFENPKGLIHGCSKDNRNDTE
Sbjct: 721  SISLVPGTDYGTQESISLLEVSTLGKAKTEPNKCVSQCAAFENPKGLIHGCSKDNRNDTE 780

Query: 828  GFKYPLGHEVNHSRETSIEMEESELDAQYLQNTFKVSKRQSFAPFSNPGNAEEECATFSA 887
            GFKYPLGHEVNHSRETSIEMEESELDAQYLQNTFKVSKRQSFAPFSNPGNAEEECATFSA
Sbjct: 781  GFKYPLGHEVNHSRETSIEMEESELDAQYLQNTFKVSKRQSFAPFSNPGNAEEECATFSA 840

Query: 888  HSGSLKKQSPKVTFECEQKEENQGKNESNIKPVQTVNITAGFPVVGQKDKPVDNAKCSIK 947
            HSGSLKKQSPKVTFECEQKEENQGKNESNIKPVQTVNITAGFPVVGQKDKPVDNAKCSIK
Sbjct: 841  HSGSLKKQSPKVTFECEQKEENQGKNESNIKPVQTVNITAGFPVVGQKDKPVDNAKCSIK 900

Query: 948  GGSRFCLSSQFRGNETGLITPNKHGLLQNPYRIPPLFPIKSFVKTKCKKNLLEENFEEHS 1007
            GGSRFCLSSQFRGNETGLITPNKHGLLQNPYRIPPLFPIKSFVKTKCKKNLLEENFEEHS
Sbjct: 901  GGSRFCLSSQFRGNETGLITPNKHGLLQNPYRIPPLFPIKSFVKTKCKKNLLEENFEEHS 960

Query: 1008 MSPEREMGNENIPSTVSTISRNNIRENVFKEASSSNINEVGSSTNEVGSSINEIGSSDEN 1067
            MSPEREMGNENIPSTVSTISRNNIRENVFKEASSSNINEVGSSTNEVGSSINEIGSSDEN
Sbjct: 961  MSPEREMGNENIPSTVSTISRNNIRENVFKEASSSNINEVGSSTNEVGSSINEIGSSDEN 1020

Query: 1068 IQAELGRNRGPKLNAMLRLGVLQPEVYKQSLPGSNCKHPEIKKQEYEEVVQTVNTDFSPY 1127
            IQAELGRNRGPKLNAMLRLGVLQPEVYKQSLPGSNCKHPEIKKQEYEEVVQTVNTDFSPY
Sbjct: 1021 IQAELGRNRGPKLNAMLRLGVLQPEVYKQSLPGSNCKHPEIKKQEYEEVVQTVNTDFSPY 1080

Query: 1128 LISDNLEQPMGSSHASQVCSETPDDLLDDGEIKEDTSFAENDIKESSAVFSKSVQKGELS 1187
            LISDNLEQPMGSSHASQVCSETPDDLLDDGEIKEDTSFAENDIKESSAVFSKSVQKGELS
Sbjct: 1081 LISDNLEQPMGSSHASQVCSETPDDLLDDGEIKEDTSFAENDIKESSAVFSKSVQKGELS 1140

Query: 1188 RSPSPFTHTHLAQGYRRGAKKLESSEENLSSEDEELPCFQHLLFGKVNNIPSQSTRHSTV 1247
            RSPSPFTHTHLAQGYRRGAKKLESSEENLSSEDEELPCFQHLLFGKVNNIPSQSTRHSTV
Sbjct: 1141 RSPSPFTHTHLAQGYRRGAKKLESSEENLSSEDEELPCFQHLLFGKVNNIPSQSTRHSTV 1200

Query: 1248 ATECLSKNTEENLLSLKNSLNDCSNQVILAKASQEHHLSEETKCSASLFSSQCSELEDLT 1307
            ATECLSKNTEENLLSLKNSLNDCSNQVILAKASQEHHLSEETKCSASLFSSQCSELEDLT
Sbjct: 1201 ATECLSKNTEENLLSLKNSLNDCSNQVILAKASQEHHLSEETKCSASLFSSQCSELEDLT 1260

Query: 1308 ANTNTQDPFLIGSSKQMRHQSESQGVGLSDKELVSDDEERGTGLEENNQEEQSMDSNLGE 1367
            ANTNTQDPFLIGSSKQMRHQSESQGVGLSDKELVSDDEERGTGLEENNQEEQSMDSNLGE
Sbjct: 1261 ANTNTQDPFLIGSSKQMRHQSESQGVGLSDKELVSDDEERGTGLEENNQEEQSMDSNLGE 1320

Query: 1368 AASGCESETSVSEDCSGLSSQSDILTTQQRDTMQHNLIKLQQEMAELEAVLEQHGSQPSN 1427
            AASGCESETSVSEDCSGLSSQSDILTTQQRDTMQHNLIKLQQEMAELEAVLEQHGSQPSN
Sbjct: 1321 AASGCESETSVSEDCSGLSSQSDILTTQQRDTMQHNLIKLQQEMAELEAVLEQHGSQPSN 1380

Query: 1428 SYPSIISDSSALEDLRNPEQSTSEKAVLTSQKSSEYPISQNPEGLSADKFEVSADSSTSK 1487
            SYPSIISDSSALEDLRNPEQSTSEKAVLTSQKSSEYPISQNPEGLSADKFEVSADSSTSK
Sbjct: 1381 SYPSIISDSSALEDLRNPEQSTSEKAVLTSQKSSEYPISQNPEGLSADKFEVSADSSTSK 1440

Query: 1488 NKEPGVERSSPSKCPSLDDRWYMHSCSGSLQNRNYPSQEELIKVVDVEEQQLEESGPHDL 1547
            NKEPGVERSSPSKCPSLDDRWYMHSCSGSLQNRNYPSQEELIKVVDVEEQQLEESGPHDL
Sbjct: 1441 NKEPGVERSSPSKCPSLDDRWYMHSCSGSLQNRNYPSQEELIKVVDVEEQQLEESGPHDL 1500

Query: 1548 TETSYLPRQDLEGTPYLESGISLFSDDPESDPSEDRAPESARVGNIPSSTSALKVPQLKV 1607
            TETSYLPRQDLEGTPYLESGISLFSDDPESDPSEDRAPESARVGNIPSSTSALKVPQLKV
Sbjct: 1501 TETSYLPRQDLEGTPYLESGISLFSDDPESDPSEDRAPESARVGNIPSSTSALKVPQLKV 1560

Query: 1608 AESAQSPAAAHTTDTAGYNAMEESVSREKPELTASTERVNKRMSMVVSGLTPEEFMLVYK 1667
            AESAQSPAAAHTTDTAGYNAMEESVSREKPELTASTERVNKRMSMVVSGLTPEEFMLVYK
Sbjct: 1561 AESAQSPAAAHTTDTAGYNAMEESVSREKPELTASTERVNKRMSMVVSGLTPEEFMLVYK 1620

Query: 1668 FARKHHITLTNLITEETTHVVMKTDAEFVCERTLKYFLGIAGGKWVVSYFWVTQSIKERK 1727
            FARKHHITLTNLITEETTHVVMKTDAEFVCERTLKYFLGIAGGKWVVSYFWVTQSIKERK
Sbjct: 1621 FARKHHITLTNLITEETTHVVMKTDAEFVCERTLKYFLGIAGGKWVVSYFWVTQSIKERK 1680

Query: 1728 MLNEHDFEVRGDVVNGRNHQGPKRARESQDRKIFRGLEICCYGPFTNMPTDQLEWMVQLC 1787
            MLNEHDFEVRGDVVNGRNHQGPKRARESQDRKIFRGLEICCYGPFTNMPTDQLEWMVQLC
Sbjct: 1681 MLNEHDFEVRGDVVNGRNHQGPKRARESQDRKIFRGLEICCYGPFTNMPTDQLEWMVQLC 1740

Query: 1788 GASVVKELSSFTLGTGVHPIVVVQPDAWTEDNGFHAIGQMCEAPVVTREWVLDSVALYQC 1847
            GASVVKELSSFTLGTGVHPIVVVQPDAWTEDNGFHAIGQMCEAPVVTREWVLDSVALYQC
Sbjct: 1741 GASVVKELSSFTLGTGVHPIVVVQPDAWTEDNGFHAIGQMCEAPVVTREWVLDSVALYQC 1800

Query: 1848 QELDTYLIPQIPHSHY 1863
            QELDTYLIPQIPHSHY
Sbjct: 1801 QELDTYLIPQIPHSHY 1816


>gi|237681123 breast cancer 1, early onset isoform 4 [Homo sapiens]
          Length = 759

 Score = 1008 bits (2606), Expect = 0.0
 Identities = 549/765 (71%), Positives = 594/765 (77%), Gaps = 20/765 (2%)

Query: 1108 IKKQEYEEVVQTVNTDFSPYLISDNLEQPMGSSHASQVCSETPDDLLDDGEIKEDTSFAE 1167
            ++ +E + V+  +       +  + +++P+ +      C      LL+  +        +
Sbjct: 6    LRVEEVQNVINAMQKILECPICLELIKEPVSTKCDHIFCKFCMLKLLNQKKGPSQCPLCK 65

Query: 1168 NDIK----ESSAVFSKSVQKGELSRSPSPF---THTHLAQGYRRGAKKLESSEENLSSED 1220
            NDI     + S  FS+ V+  EL +    F   T    A  Y   AKK  +S E+L  E 
Sbjct: 66   NDITKRSLQESTRFSQLVE--ELLKIICAFQLDTGLEYANSYNF-AKKENNSPEHLKDEV 122

Query: 1221 EELPCFQHLLFGK--VNNIPSQSTRHSTVATECLSKNTEENLLSLKNSLNDCSNQVILAK 1278
              +    +    K  + + P   +   T  +  LS       L  K  +      V +  
Sbjct: 123  SIIQSMGYRNRAKRLLQSEPENPSLQETSLSVQLSNLGTVRTLRTKQRIQPQKTSVYIEL 182

Query: 1279 ASQEHHLSEETKCSASLFSSQCSELEDLTANTNTQDPFLIGSSKQMRHQSESQGVGLSDK 1338
             S     SE+T   A+  S    EL  +T    T+D   + S+K+   +     V  ++ 
Sbjct: 183  GSDS---SEDTVNKATYCSVGDQELLQITPQ-GTRDEISLDSAKKAACEFSETDVTNTEH 238

Query: 1339 ELVSDDEERGTGLEENNQEEQSMDSNLGEAASGCESETSVSEDCSGLSSQSDILTTQQRD 1398
               S+++   T   E    E+  +   GEAASGCESETSVSEDCSGLSSQSDILTTQQRD
Sbjct: 239  HQPSNNDLNTT---EKRAAERHPEKYQGEAASGCESETSVSEDCSGLSSQSDILTTQQRD 295

Query: 1399 TMQHNLIKLQQEMAELEAVLEQHGSQPSNSYPSIISDSSALEDLRNPEQSTSEKAVLTSQ 1458
            TMQHNLIKLQQEMAELEAVLEQHGSQPSNSYPSIISDSSALEDLRNPEQSTSEK VLTSQ
Sbjct: 296  TMQHNLIKLQQEMAELEAVLEQHGSQPSNSYPSIISDSSALEDLRNPEQSTSEK-VLTSQ 354

Query: 1459 KSSEYPISQNPEGLSADKFEVSADSSTSKNKEPGVERSSPSKCPSLDDRWYMHSCSGSLQ 1518
            KSSEYPISQNPEGLSADKFEVSADSSTSKNKEPGVERSSPSKCPSLDDRWYMHSCSGSLQ
Sbjct: 355  KSSEYPISQNPEGLSADKFEVSADSSTSKNKEPGVERSSPSKCPSLDDRWYMHSCSGSLQ 414

Query: 1519 NRNYPSQEELIKVVDVEEQQLEESGPHDLTETSYLPRQDLEGTPYLESGISLFSDDPESD 1578
            NRNYPSQEELIKVVDVEEQQLEESGPHDLTETSYLPRQDLEGTPYLESGISLFSDDPESD
Sbjct: 415  NRNYPSQEELIKVVDVEEQQLEESGPHDLTETSYLPRQDLEGTPYLESGISLFSDDPESD 474

Query: 1579 PSEDRAPESARVGNIPSSTSALKVPQLKVAESAQSPAAAHTTDTAGYNAMEESVSREKPE 1638
            PSEDRAPESARVGNIPSSTSALKVPQLKVAESAQSPAAAHTTDTAGYNAMEESVSREKPE
Sbjct: 475  PSEDRAPESARVGNIPSSTSALKVPQLKVAESAQSPAAAHTTDTAGYNAMEESVSREKPE 534

Query: 1639 LTASTERVNKRMSMVVSGLTPEEFMLVYKFARKHHITLTNLITEETTHVVMKTDAEFVCE 1698
            LTASTERVNKRMSMVVSGLTPEEFMLVYKFARKHHITLTNLITEETTHVVMKTDAEFVCE
Sbjct: 535  LTASTERVNKRMSMVVSGLTPEEFMLVYKFARKHHITLTNLITEETTHVVMKTDAEFVCE 594

Query: 1699 RTLKYFLGIAGGKWVVSYFWVTQSIKERKMLNEHDFEVRGDVVNGRNHQGPKRARESQDR 1758
            RTLKYFLGIAGGKWVVSYFWVTQSIKERKMLNEHDFEVRGDVVNGRNHQGPKRARESQDR
Sbjct: 595  RTLKYFLGIAGGKWVVSYFWVTQSIKERKMLNEHDFEVRGDVVNGRNHQGPKRARESQDR 654

Query: 1759 KIFRGLEICCYGPFTNMPTDQLEWMVQLCGASVVKELSSFTLGTGVHPIVVVQPDAWTED 1818
            KIFRGLEICCYGPFTNMPTDQLEWMVQLCGASVVKELSSFTLGTGVHPIVVVQPDAWTED
Sbjct: 655  KIFRGLEICCYGPFTNMPTDQLEWMVQLCGASVVKELSSFTLGTGVHPIVVVQPDAWTED 714

Query: 1819 NGFHAIGQMCEAPVVTREWVLDSVALYQCQELDTYLIPQIPHSHY 1863
            NGFHAIGQMCEAPVVTREWVLDSVALYQCQELDTYLIPQIPHSHY
Sbjct: 715  NGFHAIGQMCEAPVVTREWVLDSVALYQCQELDTYLIPQIPHSHY 759



 Score =  532 bits (1371), Expect = e-150
 Identities = 335/585 (57%), Positives = 370/585 (63%), Gaps = 51/585 (8%)

Query: 1   MDLSALRVEEVQNVINAMQKILECPICLELIKEPVSTKCDHIFCKFCMLKLLNQKKGPSQ 60
           MDLSALRVEEVQNVINAMQKILECPICLELIKEPVSTKCDHIFCKFCMLKLLNQKKGPSQ
Sbjct: 1   MDLSALRVEEVQNVINAMQKILECPICLELIKEPVSTKCDHIFCKFCMLKLLNQKKGPSQ 60

Query: 61  CPLCKNDITKRSLQESTRFSQLVEELLKIICAFQLDTGLEYANSYNFAKKENNSPEHLKD 120
           CPLCKNDITKRSLQESTRFSQLVEELLKIICAFQLDTGLEYANSYNFAKKENNSPEHLKD
Sbjct: 61  CPLCKNDITKRSLQESTRFSQLVEELLKIICAFQLDTGLEYANSYNFAKKENNSPEHLKD 120

Query: 121 EVSIIQSMGYRNRAKRLLQSEPENPSLQETSLSVQLSNLGTVRTLRTKQRIQPQKTSVYI 180
           EVSIIQSMGYRNRAKRLLQSEPENPSLQETSLSVQLSNLGTVRTLRTKQRIQPQKTSVYI
Sbjct: 121 EVSIIQSMGYRNRAKRLLQSEPENPSLQETSLSVQLSNLGTVRTLRTKQRIQPQKTSVYI 180

Query: 181 ELGSDSSEDTVNKATYCSVGDQELLQITPQGTRDEISLDSAKKAACEFSETDVTNTEHHQ 240
           ELGSDSSEDTVNKATYCSVGDQELLQITPQGTRDEISLDSAKKAACEFSETDVTNTEHHQ
Sbjct: 181 ELGSDSSEDTVNKATYCSVGDQELLQITPQGTRDEISLDSAKKAACEFSETDVTNTEHHQ 240

Query: 241 PSNNDLNTTEKRAAERHPEKYQGSSVSNLHVEPCGTNTHASSLQHENSSLLLTKDR---- 296
           PSNNDLNTTEKRAAERHPEKYQG + S    E    +   S L  + S +L T+ R    
Sbjct: 241 PSNNDLNTTEKRAAERHPEKYQGEAASGCESE-TSVSEDCSGLSSQ-SDILTTQQRDTMQ 298

Query: 297 -----MNVEKAEFCNKSKQPGLARS-QHNRWAGSKETCNDRRTP--STEKKV-------- 340
                +  E AE     +Q G   S  +           D R P  ST +KV        
Sbjct: 299 HNLIKLQQEMAELEAVLEQHGSQPSNSYPSIISDSSALEDLRNPEQSTSEKVLTSQKSSE 358

Query: 341 --------DLNAD--PLCERKEWNKQKLPCSENPRDTE----DVPWITLNSSIQKVNEWF 386
                    L+AD   +      +K K P  E    ++    D  W   + S    N  +
Sbjct: 359 YPISQNPEGLSADKFEVSADSSTSKNKEPGVERSSPSKCPSLDDRWYMHSCSGSLQNRNY 418

Query: 387 SRSDELLGSDDSHDGESE-------SNAKVADVLDVLNEVDEYSGSSEKIDLLASDPHEA 439
              +EL+   D  + + E       +        D+       SG S   D   SDP E 
Sbjct: 419 PSQEELIKVVDVEEQQLEESGPHDLTETSYLPRQDLEGTPYLESGISLFSDDPESDPSED 478

Query: 440 LICKSERVHSKSVESNIEDKIFGKTYRKKASLPNLSHVTENLIIGAFVTEPQIIQERP-L 498
              +S RV      S    K+      + A  P  +H T+    G    E  + +E+P L
Sbjct: 479 RAPESARV-GNIPSSTSALKVPQLKVAESAQSPAAAHTTDT--AGYNAMEESVSREKPEL 535

Query: 499 TNKL----KRKRRPTSGLHPEDFIKKADLAVQKTPEMINQGTNQT 539
           T       KR     SGL PE+F+     A +    + N  T +T
Sbjct: 536 TASTERVNKRMSMVVSGLTPEEFMLVYKFARKHHITLTNLITEET 580


>gi|237681125 breast cancer 1, early onset isoform 5 [Homo sapiens]
          Length = 699

 Score =  828 bits (2138), Expect = 0.0
 Identities = 463/679 (68%), Positives = 508/679 (74%), Gaps = 20/679 (2%)

Query: 1108 IKKQEYEEVVQTVNTDFSPYLISDNLEQPMGSSHASQVCSETPDDLLDDGEIKEDTSFAE 1167
            ++ +E + V+  +       +  + +++P+ +      C      LL+  +        +
Sbjct: 6    LRVEEVQNVINAMQKILECPICLELIKEPVSTKCDHIFCKFCMLKLLNQKKGPSQCPLCK 65

Query: 1168 NDIK----ESSAVFSKSVQKGELSRSPSPF---THTHLAQGYRRGAKKLESSEENLSSED 1220
            NDI     + S  FS+ V+  EL +    F   T    A  Y   AKK  +S E+L  E 
Sbjct: 66   NDITKRSLQESTRFSQLVE--ELLKIICAFQLDTGLEYANSYNF-AKKENNSPEHLKDEV 122

Query: 1221 EELPCFQHLLFGK--VNNIPSQSTRHSTVATECLSKNTEENLLSLKNSLNDCSNQVILAK 1278
              +    +    K  + + P   +   T  +  LS       L  K  +      V +  
Sbjct: 123  SIIQSMGYRNRAKRLLQSEPENPSLQETSLSVQLSNLGTVRTLRTKQRIQPQKTSVYIEL 182

Query: 1279 ASQEHHLSEETKCSASLFSSQCSELEDLTANTNTQDPFLIGSSKQMRHQSESQGVGLSDK 1338
             S     SE+T   A+  S    EL  +T    T+D   + S+K+   +     V  ++ 
Sbjct: 183  GSDS---SEDTVNKATYCSVGDQELLQITPQ-GTRDEISLDSAKKAACEFSETDVTNTEH 238

Query: 1339 ELVSDDEERGTGLEENNQEEQSMDSNLGEAASGCESETSVSEDCSGLSSQSDILTTQQRD 1398
               S+++   T   E    E+  +   GEAASGCESETSVSEDCSGLSSQSDILTTQQRD
Sbjct: 239  HQPSNNDLNTT---EKRAAERHPEKYQGEAASGCESETSVSEDCSGLSSQSDILTTQQRD 295

Query: 1399 TMQHNLIKLQQEMAELEAVLEQHGSQPSNSYPSIISDSSALEDLRNPEQSTSEKAVLTSQ 1458
            TMQHNLIKLQQEMAELEAVLEQHGSQPSNSYPSIISDSSALEDLRNPEQSTSEK VLTSQ
Sbjct: 296  TMQHNLIKLQQEMAELEAVLEQHGSQPSNSYPSIISDSSALEDLRNPEQSTSEK-VLTSQ 354

Query: 1459 KSSEYPISQNPEGLSADKFEVSADSSTSKNKEPGVERSSPSKCPSLDDRWYMHSCSGSLQ 1518
            KSSEYPISQNPEGLSADKFEVSADSSTSKNKEPGVERSSPSKCPSLDDRWYMHSCSGSLQ
Sbjct: 355  KSSEYPISQNPEGLSADKFEVSADSSTSKNKEPGVERSSPSKCPSLDDRWYMHSCSGSLQ 414

Query: 1519 NRNYPSQEELIKVVDVEEQQLEESGPHDLTETSYLPRQDLEGTPYLESGISLFSDDPESD 1578
            NRNYPSQEELIKVVDVEEQQLEESGPHDLTETSYLPRQDLEGTPYLESGISLFSDDPESD
Sbjct: 415  NRNYPSQEELIKVVDVEEQQLEESGPHDLTETSYLPRQDLEGTPYLESGISLFSDDPESD 474

Query: 1579 PSEDRAPESARVGNIPSSTSALKVPQLKVAESAQSPAAAHTTDTAGYNAMEESVSREKPE 1638
            PSEDRAPESARVGNIPSSTSALKVPQLKVAESAQSPAAAHTTDTAGYNAMEESVSREKPE
Sbjct: 475  PSEDRAPESARVGNIPSSTSALKVPQLKVAESAQSPAAAHTTDTAGYNAMEESVSREKPE 534

Query: 1639 LTASTERVNKRMSMVVSGLTPEEFMLVYKFARKHHITLTNLITEETTHVVMKTDAEFVCE 1698
            LTASTERVNKRMSMVVSGLTPEEFMLVYKFARKHHITLTNLITEETTHVVMKTDAEFVCE
Sbjct: 535  LTASTERVNKRMSMVVSGLTPEEFMLVYKFARKHHITLTNLITEETTHVVMKTDAEFVCE 594

Query: 1699 RTLKYFLGIAGGKWVVSYFWVTQSIKERKMLNEHDFEVRGDVVNGRNHQGPKRARESQDR 1758
            RTLKYFLGIAGGKWVVSYFWVTQSIKERKMLNEHDFEVRGDVVNGRNHQGPKRARESQDR
Sbjct: 595  RTLKYFLGIAGGKWVVSYFWVTQSIKERKMLNEHDFEVRGDVVNGRNHQGPKRARESQDR 654

Query: 1759 KIFRGLEICCYGPFTNMPT 1777
            KIFRGLEICCYGPFTNMPT
Sbjct: 655  KIFRGLEICCYGPFTNMPT 673



 Score =  532 bits (1371), Expect = e-150
 Identities = 335/585 (57%), Positives = 370/585 (63%), Gaps = 51/585 (8%)

Query: 1   MDLSALRVEEVQNVINAMQKILECPICLELIKEPVSTKCDHIFCKFCMLKLLNQKKGPSQ 60
           MDLSALRVEEVQNVINAMQKILECPICLELIKEPVSTKCDHIFCKFCMLKLLNQKKGPSQ
Sbjct: 1   MDLSALRVEEVQNVINAMQKILECPICLELIKEPVSTKCDHIFCKFCMLKLLNQKKGPSQ 60

Query: 61  CPLCKNDITKRSLQESTRFSQLVEELLKIICAFQLDTGLEYANSYNFAKKENNSPEHLKD 120
           CPLCKNDITKRSLQESTRFSQLVEELLKIICAFQLDTGLEYANSYNFAKKENNSPEHLKD
Sbjct: 61  CPLCKNDITKRSLQESTRFSQLVEELLKIICAFQLDTGLEYANSYNFAKKENNSPEHLKD 120

Query: 121 EVSIIQSMGYRNRAKRLLQSEPENPSLQETSLSVQLSNLGTVRTLRTKQRIQPQKTSVYI 180
           EVSIIQSMGYRNRAKRLLQSEPENPSLQETSLSVQLSNLGTVRTLRTKQRIQPQKTSVYI
Sbjct: 121 EVSIIQSMGYRNRAKRLLQSEPENPSLQETSLSVQLSNLGTVRTLRTKQRIQPQKTSVYI 180

Query: 181 ELGSDSSEDTVNKATYCSVGDQELLQITPQGTRDEISLDSAKKAACEFSETDVTNTEHHQ 240
           ELGSDSSEDTVNKATYCSVGDQELLQITPQGTRDEISLDSAKKAACEFSETDVTNTEHHQ
Sbjct: 181 ELGSDSSEDTVNKATYCSVGDQELLQITPQGTRDEISLDSAKKAACEFSETDVTNTEHHQ 240

Query: 241 PSNNDLNTTEKRAAERHPEKYQGSSVSNLHVEPCGTNTHASSLQHENSSLLLTKDR---- 296
           PSNNDLNTTEKRAAERHPEKYQG + S    E    +   S L  + S +L T+ R    
Sbjct: 241 PSNNDLNTTEKRAAERHPEKYQGEAASGCESE-TSVSEDCSGLSSQ-SDILTTQQRDTMQ 298

Query: 297 -----MNVEKAEFCNKSKQPGLARS-QHNRWAGSKETCNDRRTP--STEKKV-------- 340
                +  E AE     +Q G   S  +           D R P  ST +KV        
Sbjct: 299 HNLIKLQQEMAELEAVLEQHGSQPSNSYPSIISDSSALEDLRNPEQSTSEKVLTSQKSSE 358

Query: 341 --------DLNAD--PLCERKEWNKQKLPCSENPRDTE----DVPWITLNSSIQKVNEWF 386
                    L+AD   +      +K K P  E    ++    D  W   + S    N  +
Sbjct: 359 YPISQNPEGLSADKFEVSADSSTSKNKEPGVERSSPSKCPSLDDRWYMHSCSGSLQNRNY 418

Query: 387 SRSDELLGSDDSHDGESE-------SNAKVADVLDVLNEVDEYSGSSEKIDLLASDPHEA 439
              +EL+   D  + + E       +        D+       SG S   D   SDP E 
Sbjct: 419 PSQEELIKVVDVEEQQLEESGPHDLTETSYLPRQDLEGTPYLESGISLFSDDPESDPSED 478

Query: 440 LICKSERVHSKSVESNIEDKIFGKTYRKKASLPNLSHVTENLIIGAFVTEPQIIQERP-L 498
              +S RV      S    K+      + A  P  +H T+    G    E  + +E+P L
Sbjct: 479 RAPESARV-GNIPSSTSALKVPQLKVAESAQSPAAAHTTDT--AGYNAMEESVSREKPEL 535

Query: 499 TNKL----KRKRRPTSGLHPEDFIKKADLAVQKTPEMINQGTNQT 539
           T       KR     SGL PE+F+     A +    + N  T +T
Sbjct: 536 TASTERVNKRMSMVVSGLTPEEFMLVYKFARKHHITLTNLITEET 580


>gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens]
          Length = 1301

 Score = 73.2 bits (178), Expect = 2e-12
 Identities = 132/659 (20%), Positives = 248/659 (37%), Gaps = 54/659 (8%)

Query: 1002 NFEEHSM------SPEREMGNE--NIPSTVSTISRNNIRENVFKEASSSNINEVGSSTNE 1053
            +F++ SM      S +   GN+  N  S  ++ SR +   N  +   + N ++   + ++
Sbjct: 454  DFDDKSMQGDDPNSSDESNGNDDANSESDNNSSSRGDASYNSDESKDNGNGSDSKGAEDD 513

Query: 1054 VGSSINEIGSSDENIQAELGRNRGPKLNAMLRLGVLQPEVYKQSLPGSNCKHPEIKKQEY 1113
               S ++  +SD N     G +   K ++    G         S   ++    +    + 
Sbjct: 514  DSDSTSDTNNSDSNGNGNNGNDDNDKSDS--GKGKSDSSDSDSSDSSNSSDSSDSSDSDS 571

Query: 1114 EEVVQTVNTDFSPYLISDNLEQPMGSSHASQVCSETPD-----DLLDDGEIKEDTSFAEN 1168
             +   + ++D S    SD+ +     S  S   S++ D     D  D  + K D+S +E+
Sbjct: 572  SDSNSSSDSDSSDSDSSDSSDSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSKSDSSKSES 631

Query: 1169 DIKESSAVFSKSVQKGELSRSPSPFTHTHLAQGYRRGAKKLESSEENLSSEDEELPCFQH 1228
            D  +S    SKS      S   S  + +  +      +   +SS+ + SS          
Sbjct: 632  DSSDSD---SKSDSSDSNSSDSSDNSDSSDSSNSSNSSDSSDSSDSSDSSSS-------- 680

Query: 1229 LLFGKVNNIPSQSTRHSTVATECLSKNTEENLLSLKNSLNDCSNQVILAKASQEHHLSEE 1288
                      S S+  S  +    S N+ E+  S  +S +D S+    + ++     S+ 
Sbjct: 681  ----------SDSSNSSDSSDSSDSSNSSESSDSSDSSDSDSSDSSDSSNSNSSD--SDS 728

Query: 1289 TKCSASLFSSQCSELEDLTANTNTQDPFLIGSSKQMRHQSESQGVGLSDKELVSDDEERG 1348
            +  S S  SS  S+  D + ++N+ D     SS      + S     SD    SD     
Sbjct: 729  SNSSDSSDSSNSSDSSDSSDSSNSSD-----SSDSSDSSNSSDSSDSSDSSDSSDSSNSS 783

Query: 1349 TGLEENNQEEQSMDSNLGEAASGCESETSVSEDCSGLSSQSDILTTQQRDTMQHNLIKLQ 1408
               + +N  + S  SN  ++++  +S  S     S  S+ SD  ++   D+   +     
Sbjct: 784  DSNDSSNSSDSSDSSNSSDSSNSSDSSDSSDSSDSDSSNSSD--SSNSSDSSDSSNSSDS 841

Query: 1409 QEMAELEAVLEQHGSQPSNSYPSIISDSSALEDLRNPEQSTSEKAVLTSQKSSEYPISQN 1468
             + ++     +   S  S+S  S  SDSS   D  N   S+       S  SS+   S N
Sbjct: 842  SDSSDSSDGSDSDSSNRSDSSNS--SDSSDSSDSSNSSDSSDSSDSNESSNSSDSSDSSN 899

Query: 1469 PEGLSADKFEVSADSSTSKNKEPGVERSSPSKCPSLDDRWYMHSCSGSLQNRN---YPSQ 1525
                 +     S+DSS S N     E S+ S   +  D       S S  + N     + 
Sbjct: 900  SSDSDSSDSSNSSDSSDSSNSSDSSESSNSSDNSNSSDSSNSSDSSDSSDSSNSSDSSNS 959

Query: 1526 EELIKVVDVEEQQLEESGPHDLTETSYLPRQDLEGTPYLESGISLFSDDPESDPSEDRAP 1585
             +     D  +    +S     +  S       + +   +S  S  SD  +S  S D + 
Sbjct: 960  SDSSNSSDSSDSNSSDSSDSSNSSDSSDSSDSSDSSDSSDSSNS--SDSSDSSDSSDSSN 1017

Query: 1586 ESARVGNIPSSTSALKVPQLKVAESAQSPAAAHTTDTAGYNAMEESVSREKPELTASTE 1644
             S    +  SS S+        ++S+ S  ++ ++D++  N+ + S S +  + + S++
Sbjct: 1018 SSDSSNSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSS--NSSDSSDSSDSSDSSDSSD 1074



 Score = 50.1 bits (118), Expect = 2e-05
 Identities = 90/506 (17%), Positives = 180/506 (35%), Gaps = 24/506 (4%)

Query: 1005 EHSMSPEREMGNENIPSTVSTISRNNIRENVFKEASSSNINEVGSSTNEVGSSINEIGSS 1064
            + S S      N++  S+ S+ S N+   +   ++S S+ +    S+N   SS N   SS
Sbjct: 775  DSSDSSNSSDSNDSSNSSDSSDSSNSSDSSNSSDSSDSSDSSDSDSSNSSDSS-NSSDSS 833

Query: 1065 DENIQAELGRNR----GPKLNAMLRLGVLQPEVYKQSLPGSNCKHPEIKKQEYEEVVQTV 1120
            D +  ++   +     G   ++  R           S   SN           E    + 
Sbjct: 834  DSSNSSDSSDSSDSSDGSDSDSSNRSDSSNSSDSSDSSDSSNSSDSSDSSDSNESSNSSD 893

Query: 1121 NTDFSPYLISDNLEQPMGSSHASQVCSETPDDLLDDGEIKEDTSFAENDIKESSAVFSKS 1180
            ++D S    SD+ +    S  +    S    D  +     ++++ +++     S+  S S
Sbjct: 894  SSDSSNSSDSDSSDSSNSSDSSD---SSNSSDSSESSNSSDNSNSSDSSNSSDSSDSSDS 950

Query: 1181 VQKGELSRSPSPFTHTHLAQGYRRGAKKLESSEENLSSEDEELPCFQHLLFGKVNNIPSQ 1240
                + S S      +  +      +    +S ++  S D              ++  S 
Sbjct: 951  SNSSDSSNSSDSSNSSDSSDSNSSDSSDSSNSSDSSDSSDSS------------DSSDSS 998

Query: 1241 STRHSTVATECLSKNTEENLLSLKNSLNDCSNQVILAKASQEHHLSEETKCSASLFSSQC 1300
             + +S+ +++    +   N     NS +D SN    + +S     S+ +  S S  SS  
Sbjct: 999  DSSNSSDSSDSSDSSDSSNSSDSSNS-SDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSNS 1057

Query: 1301 SELEDLTANTNTQDPFLIGSSKQMRHQSESQGVGLSDKELVSDDEERGTGLEENNQEEQS 1360
            S+  D + ++++ D      S      S+S     S     S D    +   +++    S
Sbjct: 1058 SDSSDSSDSSDSSDSSDSSDSSDSSESSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDS 1117

Query: 1361 MDSNLGEAASGCESETSVSEDCSGLSSQSDILTTQQRDTMQHNLIKLQQEMAELEAVLEQ 1420
             DS+   + S   S++S S D S  S  SD  +++  D+   +      + ++     + 
Sbjct: 1118 SDSS-NSSDSSDSSDSSDSSDSSNSSDSSD--SSESSDSSDSSDSSDSSDSSDSSDSSDS 1174

Query: 1421 HGSQPSNSYPSIISDSSALEDLRNPEQSTSEKAVLTSQKSSEYPISQNPEGLSADKFEVS 1480
              S  S+        S + +   + + S S  +  +S  S     S + +   +     S
Sbjct: 1175 SDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSNES 1234

Query: 1481 ADSSTSKNKEPGVERSSPSKCPSLDD 1506
            +DSS S +       S  S      D
Sbjct: 1235 SDSSDSSDSSDSSNSSDSSDSSDSSD 1260



 Score = 38.5 bits (88), Expect = 0.062
 Identities = 69/403 (17%), Positives = 142/403 (35%), Gaps = 5/403 (1%)

Query: 1002 NFEEHSMSPEREMGNENIPSTVSTISRNNIRENVFKEASSSNINEVGSSTNEVGSSINEI 1061
            N  +   S      + +  S  S  S ++   +    + SSN ++   S++   SS +  
Sbjct: 899  NSSDSDSSDSSNSSDSSDSSNSSDSSESSNSSDNSNSSDSSNSSDSSDSSDSSNSSDSSN 958

Query: 1062 GSSDENIQAELGRNRGPKLNAMLRLGVLQPEVYKQSLPGSNCKHPEIKKQEYEEVVQTVN 1121
             S   N       N     ++              S   S+  +        +    + +
Sbjct: 959  SSDSSNSSDSSDSNSSDSSDSSNSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSNS 1018

Query: 1122 TDFSPYLISDNLEQPMGSSHASQVCSETPDDLLDDGEIKEDTSFAENDIKESSAVFSKSV 1181
            +D S    S N      SS +S     +      D     D+S + +    S +  S   
Sbjct: 1019 SDSSNSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDS 1078

Query: 1182 QKGELSRSPSPFTHTHLAQGYRRGAKKLESSEENLSSEDEELPCFQHLLFGKVNNIPSQS 1241
                 S   S  +++  +      +   +SS+ + SS+  +            ++  S S
Sbjct: 1079 SDSSESSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDS 1138

Query: 1242 TRHSTVATECLSKNTEENLLSLKNSLNDCSNQVILAKASQEHHLSEETKCSASLFSSQCS 1301
            +  S  +    S ++ ++  S  +S  D S+    + +S   + S+ +  S S  SS  S
Sbjct: 1139 SNSSDSSDSSESSDSSDSSDSSDSS--DSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSS 1196

Query: 1302 ELEDLTANTNTQDPFLIGSSKQMRHQSESQGVGLSDKELVSDDEERGTGLEENNQEEQSM 1361
            +  D + ++++ D      S      S+S     SD    SD  +     + +N  + S 
Sbjct: 1197 DSSDSSDSSDSSDSSDSSDSSDSSDSSDSS--DSSDSNESSDSSDSSDSSDSSNSSDSSD 1254

Query: 1362 DSNLGEAASGCESET-SVSEDCSGLSSQSDILTTQQRDTMQHN 1403
             S+  ++ S    E+ S S+  +G ++ SD  +  +     H+
Sbjct: 1255 SSDSSDSTSDSNDESDSQSKSGNGNNNGSDSDSDSEGSDSNHS 1297



 Score = 36.6 bits (83), Expect = 0.23
 Identities = 67/384 (17%), Positives = 132/384 (34%), Gaps = 5/384 (1%)

Query: 1007 SMSPEREMGNENIPSTVSTISRNNIRENVFKEASSSNINEVGSSTNEVGSSINEIGSSDE 1066
            S S +    +++  S  S  S ++   N    + SSN ++  +S++   SS +   S   
Sbjct: 892  SDSSDSSNSSDSDSSDSSNSSDSSDSSNSSDSSESSNSSDNSNSSDSSNSSDSSDSSDSS 951

Query: 1067 NIQAELGRNRGPKLNAMLRLGVLQPEVYKQSLPGSNCKHPEIKKQEYEEVVQTVNTDFSP 1126
            N       +     +               S   S+           +    + ++D S 
Sbjct: 952  NSSDSSNSSDSSNSSDSSDSNSSDSSDSSNSSDSSDSSDSSDSSDSSDSSNSSDSSDSSD 1011

Query: 1127 YLISDNLEQPMGSSHASQVCSETPDDLLDDGEIKEDTSFAENDIKESSAVFSKSVQKGEL 1186
               S N      SS +S     +      D     D+S + +    S +  S        
Sbjct: 1012 SSDSSNSSDSSNSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSD 1071

Query: 1187 SRSPSPFTHTHLAQGYRRGAKKLESSEENLSSEDEELPCFQHLLFGKVNNIPSQSTRHST 1246
            S   S  + +  +      +   +SS+ + SS+  +            ++  S S+  S 
Sbjct: 1072 SSDSSDSSDSSESSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSD 1131

Query: 1247 VATECLSKNTEENLLSLKNSLNDCSNQVILAKASQEHHLSEETKCSASLFSSQCSELEDL 1306
             +    S N+ ++  S ++S  D S+    + +S     S+ +  S S  SS  S+  D 
Sbjct: 1132 SSDSSDSSNSSDSSDSSESS--DSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDS 1189

Query: 1307 TANTNTQDPFLIGSSKQMRHQSESQGVGLSDKELVSDDEERGTGLEENNQEEQSMDSNLG 1366
            + ++++ D      S      S+S     S     S D    +   E++    S DS+  
Sbjct: 1190 SDSSDSSDS---SDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSNESSDSSDSSDSSDS 1246

Query: 1367 EAASGCESETSVSEDCSGLSSQSD 1390
              +S     +  S+  S  + +SD
Sbjct: 1247 SNSSDSSDSSDSSDSTSDSNDESD 1270



 Score = 33.9 bits (76), Expect = 1.5
 Identities = 53/275 (19%), Positives = 105/275 (38%), Gaps = 30/275 (10%)

Query: 184 SDSSEDTVNKATYCSVGDQELLQITPQGT--RDEISLDSAKKAACEFSETDVTNTEHHQP 241
           S SS D+ N +      D      +   +   D  S DS+  +    S++D +N+     
Sbjct: 677 SSSSSDSSNSSDSSDSSDSSNSSESSDSSDSSDSDSSDSSDSSNSNSSDSDSSNSSDSSD 736

Query: 242 SNNDLNTTEKRAAERHPEKYQGSSVSNLHVEPCGTNTHASSLQHENSSLLLTKDRMN-VE 300
           S+N  ++++   +    +    S  SN       +++  SS   ++S+   + D  N  +
Sbjct: 737 SSNSSDSSDSSDSSNSSDSSDSSDSSN---SSDSSDSSDSSDSSDSSNSSDSNDSSNSSD 793

Query: 301 KAEFCNKSKQPGLARSQHNRWAGSKETCNDRRTPSTEKKVDLNADPLCERKEWNKQKLPC 360
            ++  N S     + S  +  +   ++ N   + ++    D                   
Sbjct: 794 SSDSSNSSDSSNSSDSSDSSDSSDSDSSNSSDSSNSSDSSD------------------- 834

Query: 361 SENPRDTEDVPWITLNSSIQKVNEWFSRSDELLGSDDSHDGESESNAKVADVLDVLNEVD 420
           S N  D+ D    + +SS    ++  +RSD    SD S   +S +++  +D  D  NE  
Sbjct: 835 SSNSSDSSD----SSDSSDGSDSDSSNRSDSSNSSDSSDSSDSSNSSDSSDSSD-SNESS 889

Query: 421 EYSGSSEKIDLLASDPHEALICKSERVHSKSVESN 455
             S SS+  +   SD  ++         S S +S+
Sbjct: 890 NSSDSSDSSNSSDSDSSDSSNSSDSSDSSNSSDSS 924



 Score = 31.6 bits (70), Expect = 7.6
 Identities = 47/277 (16%), Positives = 102/277 (36%), Gaps = 17/277 (6%)

Query: 184 SDSSEDTVNKATYCSVGDQELLQITPQGTRDEISLDSAKKAACEFSETDVTNTEHHQPSN 243
           S  S D+ N +      D      +   +    S DS+  +      +D +++ +   SN
Sbjct: 731 SSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSNSSDSSDSS----DSSDSSDSSNSSDSN 786

Query: 244 NDLNTTEKRAAERHPEKYQGSSVSNLHVEPCGTNTHASSLQHENSSLLLTKDRMNVEKAE 303
           +  N+++   +    +    S  S+        ++++S   + + S   +    + + ++
Sbjct: 787 DSSNSSDSSDSSNSSDSSNSSDSSDSSDSSDSDSSNSSDSSNSSDSSDSSNSSDSSDSSD 846

Query: 304 FCNKSKQPGLARSQHNRWAGSKETCNDRRTPSTEKKVDLNADPLCERKEWNKQKLPCSEN 363
             + S      RS  +  + S ++ +   +  +    D N          N      S N
Sbjct: 847 SSDGSDSDSSNRSDSSNSSDSSDSSDSSNSSDSSDSSDSNESS-------NSSDSSDSSN 899

Query: 364 PRDTEDVPWITLNSSIQKVNEWFSRSDELLGSDDSHDGESESNAKVADVLDVLNEVD--- 420
             D++       + S    N   S S+    SD+S+  +S +++  +D  D  N  D   
Sbjct: 900 SSDSDSSDSSNSSDSSDSSNSSDS-SESSNSSDNSNSSDSSNSSDSSDSSDSSNSSDSSN 958

Query: 421 --EYSGSSEKIDLLASDPHEALICKSERVHSKSVESN 455
             + S SS+  D  +SD  ++         S S +S+
Sbjct: 959 SSDSSNSSDSSDSNSSDSSDSSNSSDSSDSSDSSDSS 995


>gi|62865604 tripartite motif protein 31 [Homo sapiens]
          Length = 425

 Score = 64.7 bits (156), Expect = 8e-10
 Identities = 33/103 (32%), Positives = 56/103 (54%), Gaps = 11/103 (10%)

Query: 15  INAMQKILECPICLELIKEPVSTKCDHIFCKFCMLKLLNQKKGPSQCPLCKNDITKRSLQ 74
           +N +Q+ + CPICL+++++PV+  C H FC  C+ ++     G  +CPLCK  + K ++ 
Sbjct: 7   VNKLQEEVICPICLDILQKPVTIDCGHNFCLKCITQIGETSCGFFKCPLCKTSVRKNAI- 65

Query: 75  ESTRFSQLVEELLKIICAFQLDTGLEYANSYNFAKKENNSPEH 117
              RF+ L+  L++ I A Q       A+     +KE   P H
Sbjct: 66  ---RFNSLLRNLVEKIQALQ-------ASEVQSKRKEATCPRH 98


>gi|21071052 helicase-like transcription factor [Homo sapiens]
          Length = 1009

 Score = 58.9 bits (141), Expect = 4e-08
 Identities = 23/53 (43%), Positives = 37/53 (69%)

Query: 23  ECPICLELIKEPVSTKCDHIFCKFCMLKLLNQKKGPSQCPLCKNDITKRSLQE 75
           EC ICL+ +  PV T C H+FCK C+ +++  ++  ++CPLC+NDI + +L E
Sbjct: 759 ECAICLDSLTVPVITHCAHVFCKPCICQVIQNEQPHAKCPLCRNDIHEDNLLE 811


>gi|21071054 helicase-like transcription factor [Homo sapiens]
          Length = 1009

 Score = 58.9 bits (141), Expect = 4e-08
 Identities = 23/53 (43%), Positives = 37/53 (69%)

Query: 23  ECPICLELIKEPVSTKCDHIFCKFCMLKLLNQKKGPSQCPLCKNDITKRSLQE 75
           EC ICL+ +  PV T C H+FCK C+ +++  ++  ++CPLC+NDI + +L E
Sbjct: 759 ECAICLDSLTVPVITHCAHVFCKPCICQVIQNEQPHAKCPLCRNDIHEDNLLE 811


>gi|117938316 tripartite motif-containing 22 [Homo sapiens]
          Length = 498

 Score = 57.8 bits (138), Expect = 1e-07
 Identities = 24/76 (31%), Positives = 44/76 (57%), Gaps = 4/76 (5%)

Query: 18 MQKILECPICLELIKEPVSTKCDHIFCKFCMLKLLNQ----KKGPSQCPLCKNDITKRSL 73
          ++K + CPICLEL+ EP+S  C H FC+ C+   + +     +G S CP+C+      +L
Sbjct: 9  IEKEVTCPICLELLTEPLSLDCGHSFCQACITAKIKESVIISRGESSCPVCQTRFQPGNL 68

Query: 74 QESTRFSQLVEELLKI 89
          + +   + +VE + ++
Sbjct: 69 RPNRHLANIVERVKEV 84


>gi|14719418 tripartite motif protein TRIM5 isoform alpha [Homo
          sapiens]
          Length = 493

 Score = 57.0 bits (136), Expect = 2e-07
 Identities = 26/79 (32%), Positives = 46/79 (58%), Gaps = 4/79 (5%)

Query: 14 VINAMQKILECPICLELIKEPVSTKCDHIFCKFCML---KLLNQKKGPSQCPLCKNDITK 70
          ++N  +++  CPICLEL+ +P+S  C H FC+ C+    K     KG S CP+C+     
Sbjct: 6  LVNVKEEVT-CPICLELLTQPLSLDCGHSFCQACLTANHKKSMLDKGESSCPVCRISYQP 64

Query: 71 RSLQESTRFSQLVEELLKI 89
           +++ +   + LVE+L ++
Sbjct: 65 ENIRPNRHVANLVEKLREV 83


>gi|15011946 tripartite motif protein TRIM5 isoform delta [Homo
          sapiens]
          Length = 326

 Score = 56.2 bits (134), Expect = 3e-07
 Identities = 25/79 (31%), Positives = 46/79 (58%), Gaps = 4/79 (5%)

Query: 14 VINAMQKILECPICLELIKEPVSTKCDHIFCKFCML---KLLNQKKGPSQCPLCKNDITK 70
          ++N  +++  CPICLEL+ +P+S  C H FC+ C+    K     KG S CP+C+     
Sbjct: 6  LVNVKEEVT-CPICLELLTQPLSLDCGHSFCQACLTANHKKSMLDKGESSCPVCRISYQP 64

Query: 71 RSLQESTRFSQLVEELLKI 89
           +++ +   + +VE+L ++
Sbjct: 65 ENIRPNRHVANIVEKLREV 83


>gi|15011944 tripartite motif protein TRIM5 isoform gamma [Homo
          sapiens]
          Length = 347

 Score = 56.2 bits (134), Expect = 3e-07
 Identities = 25/79 (31%), Positives = 46/79 (58%), Gaps = 4/79 (5%)

Query: 14 VINAMQKILECPICLELIKEPVSTKCDHIFCKFCML---KLLNQKKGPSQCPLCKNDITK 70
          ++N  +++  CPICLEL+ +P+S  C H FC+ C+    K     KG S CP+C+     
Sbjct: 6  LVNVKEEVT-CPICLELLTQPLSLDCGHSFCQACLTANHKKSMLDKGESSCPVCRISYQP 64

Query: 71 RSLQESTRFSQLVEELLKI 89
           +++ +   + +VE+L ++
Sbjct: 65 ENIRPNRHVANIVEKLREV 83


>gi|30023818 tripartite motif protein 50A [Homo sapiens]
          Length = 487

 Score = 56.2 bits (134), Expect = 3e-07
 Identities = 22/65 (33%), Positives = 38/65 (58%)

Query: 22 LECPICLELIKEPVSTKCDHIFCKFCMLKLLNQKKGPSQCPLCKNDITKRSLQESTRFSQ 81
          L+CPICLE+ KEP+  +C H +CK C++ L        +CP+C+  +   S   +   ++
Sbjct: 14 LQCPICLEVFKEPLMLQCGHSYCKGCLVSLSCHLDAELRCPVCRQAVDGSSSLPNVSLAR 73

Query: 82 LVEEL 86
          ++E L
Sbjct: 74 VIEAL 78


>gi|157266328 BRCA1 associated RING domain 1 [Homo sapiens]
          Length = 777

 Score = 54.7 bits (130), Expect = 8e-07
 Identities = 41/166 (24%), Positives = 76/166 (45%), Gaps = 15/166 (9%)

Query: 1630 ESVSREKPELTASTERVNKRMSMVVSGLTPEEFMLVYKFARKHHITLTNLITEETTHVVM 1689
            ES S     +  + +R +  + ++ SGL+ E+  ++ + A               THVV+
Sbjct: 550  ESSSASHCSVMNTGQRRDGPLVLIGSGLSSEQQKMLSELAVILKAKKYTEFDSTVTHVVV 609

Query: 1690 KTDAEFVCERTLKYFLGIAGGKWVVSYFWVTQSIKERKMLNEHDFEVRGDVVNGRNHQGP 1749
              DA    + TLK  LGI  G W++ + WV   ++ +    E  +E+          +GP
Sbjct: 610  PGDA---VQSTLKCMLGILNGCWILKFEWVKACLRRKVCEQEEKYEI---------PEGP 657

Query: 1750 KRARESQDR---KIFRGLEICCYGPFTNMPTDQLEWMVQLCGASVV 1792
            +R+R ++++   K+F G     +G F + P D L  +V   G  ++
Sbjct: 658  RRSRLNREQLLPKLFDGCYFYLWGTFKHHPKDNLIKLVTAGGGQIL 703



 Score = 39.7 bits (91), Expect = 0.028
 Identities = 18/76 (23%), Positives = 39/76 (51%), Gaps = 6/76 (7%)

Query: 15  INAMQKILECPICLELIKEPVST-KCDHIFCKFCMLKLLNQKKGPSQCPLCKNDITKRSL 73
           ++ ++K+L C  C  +++EPV    C+HIFC  C+   +      + CP+C      + L
Sbjct: 41  LDRLEKLLRCSRCTNILREPVCLGGCEHIFCSNCVSDCIG-----TGCPVCYTPAWIQDL 95

Query: 74  QESTRFSQLVEELLKI 89
           + + +   +++   K+
Sbjct: 96  KINRQLDSMIQLCSKL 111


>gi|145275183 tripartite motif protein 34 isoform 3 [Homo sapiens]
          Length = 270

 Score = 54.3 bits (129), Expect = 1e-06
 Identities = 25/76 (32%), Positives = 41/76 (53%), Gaps = 4/76 (5%)

Query: 18 MQKILECPICLELIKEPVSTKCDHIFCKFCML----KLLNQKKGPSQCPLCKNDITKRSL 73
          +Q+ + CPICLEL+ EP+S  C H  C+ C+     + +    G S CP+C    +   L
Sbjct: 9  VQEEVTCPICLELLTEPLSLDCGHSLCRACITVSNKEAVTSMGGKSSCPVCGISYSFEHL 68

Query: 74 QESTRFSQLVEELLKI 89
          Q +   + +VE L ++
Sbjct: 69 QANQHLANIVERLKEV 84


>gi|51477687 tripartite motif protein 34 isoform 1 [Homo sapiens]
          Length = 488

 Score = 54.3 bits (129), Expect = 1e-06
 Identities = 25/76 (32%), Positives = 41/76 (53%), Gaps = 4/76 (5%)

Query: 18 MQKILECPICLELIKEPVSTKCDHIFCKFCML----KLLNQKKGPSQCPLCKNDITKRSL 73
          +Q+ + CPICLEL+ EP+S  C H  C+ C+     + +    G S CP+C    +   L
Sbjct: 9  VQEEVTCPICLELLTEPLSLDCGHSLCRACITVSNKEAVTSMGGKSSCPVCGISYSFEHL 68

Query: 74 QESTRFSQLVEELLKI 89
          Q +   + +VE L ++
Sbjct: 69 QANQHLANIVERLKEV 84


>gi|18087807 tripartite motif protein 34 isoform 1 [Homo sapiens]
          Length = 488

 Score = 54.3 bits (129), Expect = 1e-06
 Identities = 25/76 (32%), Positives = 41/76 (53%), Gaps = 4/76 (5%)

Query: 18 MQKILECPICLELIKEPVSTKCDHIFCKFCML----KLLNQKKGPSQCPLCKNDITKRSL 73
          +Q+ + CPICLEL+ EP+S  C H  C+ C+     + +    G S CP+C    +   L
Sbjct: 9  VQEEVTCPICLELLTEPLSLDCGHSLCRACITVSNKEAVTSMGGKSSCPVCGISYSFEHL 68

Query: 74 QESTRFSQLVEELLKI 89
          Q +   + +VE L ++
Sbjct: 69 QANQHLANIVERLKEV 84


>gi|14670266 tripartite motif protein TRIM4 isoform alpha [Homo
          sapiens]
          Length = 500

 Score = 54.3 bits (129), Expect = 1e-06
 Identities = 23/68 (33%), Positives = 40/68 (58%)

Query: 18 MQKILECPICLELIKEPVSTKCDHIFCKFCMLKLLNQKKGPSQCPLCKNDITKRSLQEST 77
          +Q+ L CPICL+  ++PVS +C H FC+ C+ +      GP  CP C++     +L+ + 
Sbjct: 6  IQEELTCPICLDYFQDPVSIECGHNFCRGCLHRNWAPGGGPFPCPECRHPSAPAALRPNW 65

Query: 78 RFSQLVEE 85
            ++L E+
Sbjct: 66 ALARLTEK 73


>gi|15011941 tripartite motif protein TRIM4 isoform beta [Homo
          sapiens]
          Length = 474

 Score = 54.3 bits (129), Expect = 1e-06
 Identities = 23/68 (33%), Positives = 40/68 (58%)

Query: 18 MQKILECPICLELIKEPVSTKCDHIFCKFCMLKLLNQKKGPSQCPLCKNDITKRSLQEST 77
          +Q+ L CPICL+  ++PVS +C H FC+ C+ +      GP  CP C++     +L+ + 
Sbjct: 6  IQEELTCPICLDYFQDPVSIECGHNFCRGCLHRNWAPGGGPFPCPECRHPSAPAALRPNW 65

Query: 78 RFSQLVEE 85
            ++L E+
Sbjct: 66 ALARLTEK 73


>gi|51477690 tripartite motif-containing 6 and tripartite
           motif-containing 34 [Homo sapiens]
          Length = 842

 Score = 54.3 bits (129), Expect = 1e-06
 Identities = 25/76 (32%), Positives = 41/76 (53%), Gaps = 4/76 (5%)

Query: 18  MQKILECPICLELIKEPVSTKCDHIFCKFCML----KLLNQKKGPSQCPLCKNDITKRSL 73
           +Q+ + CPICLEL+ EP+S  C H  C+ C+     + +    G S CP+C    +   L
Sbjct: 363 VQEEVTCPICLELLTEPLSLDCGHSLCRACITVSNKEAVTSMGGKSSCPVCGISYSFEHL 422

Query: 74  QESTRFSQLVEELLKI 89
           Q +   + +VE L ++
Sbjct: 423 QANQHLANIVERLKEV 438



 Score = 52.8 bits (125), Expect = 3e-06
 Identities = 23/81 (28%), Positives = 46/81 (56%), Gaps = 4/81 (4%)

Query: 14  VINAMQKILECPICLELIKEPVSTKCDHIFCKFCML----KLLNQKKGPSQCPLCKNDIT 69
           V+  +++ + CPICLEL+ EP+S  C H FC+ C+     + +  ++G   CP+C+    
Sbjct: 33  VLVDIREEVTCPICLELLTEPLSIDCGHSFCQACITPNGRESVIGQEGERSCPVCQTSYQ 92

Query: 70  KRSLQESTRFSQLVEELLKII 90
             +L+ +   + +V  L +++
Sbjct: 93  PGNLRPNRHLANIVRRLREVV 113


>gi|21630277 tripartite motif-containing 11 [Homo sapiens]
          Length = 468

 Score = 53.9 bits (128), Expect = 1e-06
 Identities = 22/67 (32%), Positives = 38/67 (56%)

Query: 18 MQKILECPICLELIKEPVSTKCDHIFCKFCMLKLLNQKKGPSQCPLCKNDITKRSLQEST 77
          +Q+   C ICL+   +PV T C H FC+ C+ +   Q +GP  CP C+    +R+L+ + 
Sbjct: 10 LQEEATCAICLDYFTDPVMTDCGHNFCRECIRRCWGQPEGPYACPECRELSPQRNLRPNR 69

Query: 78 RFSQLVE 84
            +++ E
Sbjct: 70 PLAKMAE 76


>gi|15208660 tripartite motif protein 21 [Homo sapiens]
          Length = 475

 Score = 53.9 bits (128), Expect = 1e-06
 Identities = 25/75 (33%), Positives = 44/75 (58%), Gaps = 2/75 (2%)

Query: 15 INAMQKILECPICLELIKEPVSTKCDHIFCKFCMLKLLNQKKGPSQCPLCKNDITKRSLQ 74
          +  M + + CPICL+   EPVS +C H FC+ C+ ++   K G S CP+C+     ++L+
Sbjct: 7  LTMMWEEVTCPICLDPFVEPVSIECGHSFCQECISQV--GKGGGSVCPVCRQRFLLKNLR 64

Query: 75 ESTRFSQLVEELLKI 89
           + + + +V  L +I
Sbjct: 65 PNRQLANMVNNLKEI 79


>gi|25777698 tripartite motif-containing 39 isoform 2 [Homo
          sapiens]
          Length = 488

 Score = 53.9 bits (128), Expect = 1e-06
 Identities = 23/67 (34%), Positives = 36/67 (53%)

Query: 18 MQKILECPICLELIKEPVSTKCDHIFCKFCMLKLLNQKKGPSQCPLCKNDITKRSLQEST 77
          +Q    C +CLE +KEPV  +C H FCK C+ +     +    CP+C+     RSL+ + 
Sbjct: 23 LQVEASCSVCLEYLKEPVIIECGHNFCKACITRWWEDLERDFPCPVCRKTSRYRSLRPNR 82

Query: 78 RFSQLVE 84
          +   +VE
Sbjct: 83 QLGSMVE 89


>gi|25777696 tripartite motif-containing 39 isoform 1 [Homo
          sapiens]
          Length = 518

 Score = 53.9 bits (128), Expect = 1e-06
 Identities = 23/67 (34%), Positives = 36/67 (53%)

Query: 18 MQKILECPICLELIKEPVSTKCDHIFCKFCMLKLLNQKKGPSQCPLCKNDITKRSLQEST 77
          +Q    C +CLE +KEPV  +C H FCK C+ +     +    CP+C+     RSL+ + 
Sbjct: 23 LQVEASCSVCLEYLKEPVIIECGHNFCKACITRWWEDLERDFPCPVCRKTSRYRSLRPNR 82

Query: 78 RFSQLVE 84
          +   +VE
Sbjct: 83 QLGSMVE 89


>gi|4508005 tripartite motif-containing 26 [Homo sapiens]
          Length = 539

 Score = 53.9 bits (128), Expect = 1e-06
 Identities = 20/75 (26%), Positives = 42/75 (56%)

Query: 15 INAMQKILECPICLELIKEPVSTKCDHIFCKFCMLKLLNQKKGPSQCPLCKNDITKRSLQ 74
          + ++++ + C ICL+ +++PV+  C H+FC+ C   +         CPLCK    K +++
Sbjct: 7  LRSLEEEVTCSICLDYLRDPVTIDCGHVFCRSCTTDVRPISGSRPVCPLCKKPFKKENIR 66

Query: 75 ESTRFSQLVEELLKI 89
             + + LVE + ++
Sbjct: 67 PVWQLASLVENIERL 81


>gi|6005747 ring finger protein 2 [Homo sapiens]
          Length = 336

 Score = 53.5 bits (127), Expect = 2e-06
 Identities = 44/145 (30%), Positives = 71/145 (48%), Gaps = 14/145 (9%)

Query: 22  LECPICLELIKEPVSTK-CDHIFCKFCMLKLLNQKKGPSQCPLC-KNDITKRSLQESTRF 79
           L CPICL+++K  ++TK C H FC  C++  L  + G  +CP C K  ++KRSL+    F
Sbjct: 49  LMCPICLDMLKNTMTTKECLHRFCADCIITAL--RSGNKECPTCRKKLVSKRSLRPDPNF 106

Query: 80  SQLVEELLKIICAFQL--DTGLEYANSYNFAKKENNSPEHLKDEVSIIQSMGYRNRAKRL 137
             L+ ++      ++   +  L   N +N       +  H  +E   IQ+M   NR +R 
Sbjct: 107 DALISKIYPSRDEYEAHQERVLARINKHN----NQQALSHSIEEGLKIQAM---NRLQRG 159

Query: 138 LQSEPENPS-LQETSLSVQLSNLGT 161
            + + EN S  ++   S   SN  T
Sbjct: 160 KKQQIENGSGAEDNGDSSHCSNAST 184


>gi|87080813 LON peptidase N-terminal domain and ring finger 1 [Homo
           sapiens]
          Length = 773

 Score = 53.5 bits (127), Expect = 2e-06
 Identities = 25/65 (38%), Positives = 36/65 (55%), Gaps = 3/65 (4%)

Query: 23  ECPICLELIKEPVSTKCDHIFCKFCMLKLLNQKKGPSQCPLCKNDITKRSLQESTRFSQL 82
           EC +C+ L  EPV+T C H FCK C+ + L+       CPLCK  + +         +QL
Sbjct: 478 ECSLCMRLFFEPVTTPCGHSFCKNCLERCLDH---APYCPLCKESLKEYLADRRYCVTQL 534

Query: 83  VEELL 87
           +EEL+
Sbjct: 535 LEELI 539



 Score = 34.3 bits (77), Expect = 1.2
 Identities = 14/46 (30%), Positives = 25/46 (54%), Gaps = 5/46 (10%)

Query: 21  ILECPICLELIKEPVSTKCDHIFCKFCMLKLLNQKKGPSQCPLCKN 66
           +L C  C   + EPV+  C H +C+ C+ + L      ++C LC++
Sbjct: 120 LLRCLGCRGFLSEPVTVPCGHSYCRRCLRRELR-----ARCRLCRD 160


>gi|18079262 tripartite motif-containing 6 isoform 2 [Homo
          sapiens]
          Length = 488

 Score = 52.8 bits (125), Expect = 3e-06
 Identities = 23/81 (28%), Positives = 46/81 (56%), Gaps = 4/81 (4%)

Query: 14 VINAMQKILECPICLELIKEPVSTKCDHIFCKFCML----KLLNQKKGPSQCPLCKNDIT 69
          V+  +++ + CPICLEL+ EP+S  C H FC+ C+     + +  ++G   CP+C+    
Sbjct: 5  VLVDIREEVTCPICLELLTEPLSIDCGHSFCQACITPNGRESVIGQEGERSCPVCQTSYQ 64

Query: 70 KRSLQESTRFSQLVEELLKII 90
            +L+ +   + +V  L +++
Sbjct: 65 PGNLRPNRHLANIVRRLREVV 85


>gi|51477692 tripartite motif-containing 6 isoform 1 [Homo sapiens]
          Length = 516

 Score = 52.8 bits (125), Expect = 3e-06
 Identities = 23/81 (28%), Positives = 46/81 (56%), Gaps = 4/81 (4%)

Query: 14  VINAMQKILECPICLELIKEPVSTKCDHIFCKFCML----KLLNQKKGPSQCPLCKNDIT 69
           V+  +++ + CPICLEL+ EP+S  C H FC+ C+     + +  ++G   CP+C+    
Sbjct: 33  VLVDIREEVTCPICLELLTEPLSIDCGHSFCQACITPNGRESVIGQEGERSCPVCQTSYQ 92

Query: 70  KRSLQESTRFSQLVEELLKII 90
             +L+ +   + +V  L +++
Sbjct: 93  PGNLRPNRHLANIVRRLREVV 113


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.308    0.125    0.351 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 72,170,986
Number of Sequences: 37866
Number of extensions: 3377034
Number of successful extensions: 11634
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 193
Number of HSP's successfully gapped in prelim test: 364
Number of HSP's that attempted gapping in prelim test: 10671
Number of HSP's gapped (non-prelim): 1326
length of query: 1863
length of database: 18,247,518
effective HSP length: 117
effective length of query: 1746
effective length of database: 13,817,196
effective search space: 24124824216
effective search space used: 24124824216
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.7 bits)
S2: 69 (31.2 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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