Guide to the Human Genome
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Name: BRCA1 Sequence: fasta or formatted (1816aa) NCBI GI: 237681121
Description:

breast cancer 1, early onset isoform 3

Referenced in:

DNases, Recombination, and DNA Repair
Mammary Tissues
Ring Finger Proteins

Other entries for this name:
alt prot [1884aa] breast cancer 1, early onset isoform 2
alt prot [759aa] breast cancer 1, early onset isoform 4
alt prot [699aa] breast cancer 1, early onset isoform 5
alt prot [1863aa] breast cancer 1, early onset isoform 1
Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine             4.5         82           3
 C cysteine            2.1         39           2
 D aspartate           4.6         83           2
 E glutamate          10.6        193           3
 F phenylalanine       2.6         47           1
 G glycine             4.8         87           2
 H histidine           2.6         48           2
 I isoleucine          4.0         72           2
 K lysine              7.3        133           4
 L leucine             8.3        151           3
 M methionine          1.5         28           1
 N asparagine          6.6        119           2
 P proline             5.2         94           2
 Q glutamine           5.2         95           2
 R arginine            4.1         75           2
 S serine             12.2        222           3
 T threonine           6.1        110           2
 V valine              5.3         97           3
 W tryptophan          0.6         10           1
 Y tyrosine            1.7         31           1
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   breast cancer 1, early onset isoform 3 
BRCA1                 1.000   breast cancer 1, early onset isoform 1 
BRCA1                 0.996   breast cancer 1, early onset isoform 2 
BRCA1                 0.273   breast cancer 1, early onset isoform 4 
BRCA1                 0.223   breast cancer 1, early onset isoform 5 
DSPP                  0.013   dentin sialophosphoprotein preproprotein 
BARD1                 0.008   BRCA1 associated RING domain 1 
ATRX                  0.006   transcriptional regulator ATRX isoform 2 
ATRX                  0.006   transcriptional regulator ATRX isoform 1 
EEA1                  0.006   early endosome antigen 1, 162kD 
MCPH1                 0.006   microcephalin 
LMTK2                 0.006   lemur tyrosine kinase 2 
SYCP2                 0.006   synaptonemal complex protein 2 
GCC2                  0.006   GRIP and coiled-coil domain-containing 2 
MAP9                  0.005   aster-associated protein 
CMYA5                 0.005   cardiomyopathy associated 5 
CCDC144A              0.005   coiled-coil domain containing 144A 
IWS1                  0.005   IWS1 homolog 
PACS2                 0.005   phosphofurin acidic cluster sorting protein 2 isofo...
EPS15                 0.005   epidermal growth factor receptor pathway substrate 15...
CEP110                0.005   centrosomal protein 110kDa 
KIF20B                0.005   M-phase phosphoprotein 1 
CCDC110               0.005   coiled-coil domain containing 110 isoform a 
PCLO                  0.004   piccolo isoform 2 
PCLO                  0.004   piccolo isoform 1 
KTN1                  0.004   kinectin 1 isoform a 
KTN1                  0.004   kinectin 1 isoform c 
KTN1                  0.004   kinectin 1 isoform a 
EPS15                 0.004   epidermal growth factor receptor pathway substrate ...
TP53BP1               0.004   tumor protein p53 binding protein 1 isoform 1 [Homo...
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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