Guide to the Human Genome
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Name: BRCA1 Sequence: fasta or formatted (1884aa) NCBI GI: 237681119
Description:

breast cancer 1, early onset isoform 2

Referenced in:

DNases, Recombination, and DNA Repair
Mammary Tissues
Ring Finger Proteins

Other entries for this name:
alt prot [1816aa] breast cancer 1, early onset isoform 3
alt prot [759aa] breast cancer 1, early onset isoform 4
alt prot [699aa] breast cancer 1, early onset isoform 5
alt prot [1863aa] breast cancer 1, early onset isoform 1
Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine             4.4         83           3
 C cysteine            2.3         44           2
 D aspartate           4.6         86           2
 E glutamate          10.6        199           3
 F phenylalanine       2.7         50           1
 G glycine             4.7         88           2
 H histidine           2.8         52           2
 I isoleucine          4.2         79           2
 K lysine              7.3        138           4
 L leucine             8.3        156           3
 M methionine          1.6         31           1
 N asparagine          6.5        123           2
 P proline             5.1         97           2
 Q glutamine           5.2         98           2
 R arginine            4.2         79           2
 S serine             12.1        228           3
 T threonine           5.9        111           2
 V valine              5.4        101           3
 W tryptophan          0.5         10           1
 Y tyrosine            1.6         31           1
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   breast cancer 1, early onset isoform 2 
BRCA1                 0.985   breast cancer 1, early onset isoform 1 
BRCA1                 0.959   breast cancer 1, early onset isoform 3 
BRCA1                 0.261   breast cancer 1, early onset isoform 4 
BRCA1                 0.212   breast cancer 1, early onset isoform 5 
DSPP                  0.014   dentin sialophosphoprotein preproprotein 
TRIM31                0.011   tripartite motif protein 31 
HLTF                  0.009   helicase-like transcription factor 
HLTF                  0.009   helicase-like transcription factor 
TRIM22                0.009   tripartite motif-containing 22 
TRIM5                 0.009   tripartite motif protein TRIM5 isoform alpha 
TRIM5                 0.008   tripartite motif protein TRIM5 isoform delta 
TRIM5                 0.008   tripartite motif protein TRIM5 isoform gamma 
TRIM50                0.008   tripartite motif protein 50A 
BARD1                 0.008   BRCA1 associated RING domain 1 
TRIM34                0.008   tripartite motif protein 34 isoform 3 
TRIM34                0.008   tripartite motif protein 34 isoform 1 
TRIM34                0.008   tripartite motif protein 34 isoform 1 
TRIM4                 0.008   tripartite motif protein TRIM4 isoform alpha 
TRIM4                 0.008   tripartite motif protein TRIM4 isoform beta 
TRIM6-TRIM34          0.008   tripartite motif-containing 6 and tripartite motif-c...
TRIM11                0.008   tripartite motif-containing 11 
TRIM21                0.008   tripartite motif protein 21 
TRIM39                0.008   tripartite motif-containing 39 isoform 2 
TRIM39                0.008   tripartite motif-containing 39 isoform 1 
TRIM26                0.008   tripartite motif-containing 26 
RNF2                  0.008   ring finger protein 2 
LONRF1                0.008   LON peptidase N-terminal domain and ring finger 1 [H...
TRIM6                 0.007   tripartite motif-containing 6 isoform 2 
TRIM6                 0.007   tripartite motif-containing 6 isoform 1 
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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