Guide to the Human Genome
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Search of human proteins with 65288071

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|65288071 tensin 3 [Homo sapiens]
         (1445 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|65288071 tensin 3 [Homo sapiens]                                  2929   0.0  
gi|66529407 tensin [Homo sapiens]                                     689   0.0  
gi|38787970 tensin like C1 domain containing phosphatase isoform...   461   e-129
gi|38787957 tensin like C1 domain containing phosphatase isoform...   461   e-129
gi|38787941 tensin like C1 domain containing phosphatase isoform...   461   e-129
gi|157738639 tensin 4 [Homo sapiens]                                  319   1e-86
gi|73765544 phosphatase and tensin homolog [Homo sapiens]             145   2e-34
gi|157384971 cyclin G associated kinase [Homo sapiens]                136   2e-31
gi|40549435 transmembrane phosphatase with tensin homology isofo...   122   3e-27
gi|40549433 transmembrane phosphatase with tensin homology isofo...   122   3e-27
gi|109689707 transmembrane phosphatase with tensin homology isof...   122   3e-27
gi|7662146 DnaJ (Hsp40) homolog, subfamily C, member 6 [Homo sap...   121   4e-27
gi|213972593 TPTE and PTEN homologous inositol lipid phosphatase...   119   3e-26
gi|213972591 TPTE and PTEN homologous inositol lipid phosphatase...   119   3e-26
gi|213972589 TPTE and PTEN homologous inositol lipid phosphatase...   119   3e-26
gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi...    60   2e-08
gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapi...    59   3e-08
gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapi...    55   5e-07
gi|83367077 mucin 16 [Homo sapiens]                                    53   2e-06
gi|20143482 melanoma antigen family E, 1 [Homo sapiens]                52   4e-06
gi|54860079 nadrin isoform 1 [Homo sapiens]                            52   5e-06
gi|239743293 PREDICTED: mucin 12 [Homo sapiens]                        51   7e-06
gi|188536004 zinc finger protein 469 [Homo sapiens]                    50   1e-05
gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens]        50   2e-05
gi|239508976 PREDICTED: mucin 12, cell surface associated [Homo ...    49   4e-05
gi|91982772 mucin 17 [Homo sapiens]                                    49   4e-05
gi|163965366 nascent polypeptide-associated complex alpha subuni...    49   4e-05
gi|54860105 nadrin isoform 2 [Homo sapiens]                            49   5e-05
gi|31324577 molecule interacting with Rab13 [Homo sapiens]             49   5e-05
gi|68989256 ras inhibitor RIN1 [Homo sapiens]                          48   6e-05

>gi|65288071 tensin 3 [Homo sapiens]
          Length = 1445

 Score = 2929 bits (7593), Expect = 0.0
 Identities = 1445/1445 (100%), Positives = 1445/1445 (100%)

Query: 1    MEEGHGLDLTYITERIIAVSFPAGCSEESYLHNLQEVTRMLKSKHGDNYLVLNLSEKRYD 60
            MEEGHGLDLTYITERIIAVSFPAGCSEESYLHNLQEVTRMLKSKHGDNYLVLNLSEKRYD
Sbjct: 1    MEEGHGLDLTYITERIIAVSFPAGCSEESYLHNLQEVTRMLKSKHGDNYLVLNLSEKRYD 60

Query: 61   LTKLNPKIMDVGWPELHAPPLDKMCTICKAQESWLNSNLQHVVVIHCRGGKGRIGVVISS 120
            LTKLNPKIMDVGWPELHAPPLDKMCTICKAQESWLNSNLQHVVVIHCRGGKGRIGVVISS
Sbjct: 61   LTKLNPKIMDVGWPELHAPPLDKMCTICKAQESWLNSNLQHVVVIHCRGGKGRIGVVISS 120

Query: 121  YMHFTNVSASADQALDRFAMKKFYDDKVSALMQPSQKRYVQFLSGLLSGSVKMNASPLFL 180
            YMHFTNVSASADQALDRFAMKKFYDDKVSALMQPSQKRYVQFLSGLLSGSVKMNASPLFL
Sbjct: 121  YMHFTNVSASADQALDRFAMKKFYDDKVSALMQPSQKRYVQFLSGLLSGSVKMNASPLFL 180

Query: 181  HFVILHGTPNFDTGGVCRPFLKLYQAMQPVYTSGIYNVGPENPSRICIVIEPAQLLKGDV 240
            HFVILHGTPNFDTGGVCRPFLKLYQAMQPVYTSGIYNVGPENPSRICIVIEPAQLLKGDV
Sbjct: 181  HFVILHGTPNFDTGGVCRPFLKLYQAMQPVYTSGIYNVGPENPSRICIVIEPAQLLKGDV 240

Query: 241  MVKCYHKKYRSATRDVIFRLQFHTGAVQGYGLVFGKEDLDNASKDDRFPDYGKVELVFSA 300
            MVKCYHKKYRSATRDVIFRLQFHTGAVQGYGLVFGKEDLDNASKDDRFPDYGKVELVFSA
Sbjct: 241  MVKCYHKKYRSATRDVIFRLQFHTGAVQGYGLVFGKEDLDNASKDDRFPDYGKVELVFSA 300

Query: 301  TPEKIQGSEHLYNDHGVIVDYNTTDPLIRWDSYENLSADGEVLHTQGPVDGSLYAKVRKK 360
            TPEKIQGSEHLYNDHGVIVDYNTTDPLIRWDSYENLSADGEVLHTQGPVDGSLYAKVRKK
Sbjct: 301  TPEKIQGSEHLYNDHGVIVDYNTTDPLIRWDSYENLSADGEVLHTQGPVDGSLYAKVRKK 360

Query: 361  SSSDPGIPGGPQAIPATNSPDHSDHTLSVSSDSGHSTASARTDKTEERLAPGTRRGLSAQ 420
            SSSDPGIPGGPQAIPATNSPDHSDHTLSVSSDSGHSTASARTDKTEERLAPGTRRGLSAQ
Sbjct: 361  SSSDPGIPGGPQAIPATNSPDHSDHTLSVSSDSGHSTASARTDKTEERLAPGTRRGLSAQ 420

Query: 421  EKAELDQLLSGFGLEDPGSSLKEMTDARSKYSGTRHVVPAQVHVNGDAALKDRETDILDD 480
            EKAELDQLLSGFGLEDPGSSLKEMTDARSKYSGTRHVVPAQVHVNGDAALKDRETDILDD
Sbjct: 421  EKAELDQLLSGFGLEDPGSSLKEMTDARSKYSGTRHVVPAQVHVNGDAALKDRETDILDD 480

Query: 481  EMPHHDLHSVDSLGTLSSSEGPQSAHLGPFTCHKSSQNSLLSDGFGSNVGEDPQGTLVPD 540
            EMPHHDLHSVDSLGTLSSSEGPQSAHLGPFTCHKSSQNSLLSDGFGSNVGEDPQGTLVPD
Sbjct: 481  EMPHHDLHSVDSLGTLSSSEGPQSAHLGPFTCHKSSQNSLLSDGFGSNVGEDPQGTLVPD 540

Query: 541  LGLGMDGPYERERTFGSREPKQPQPLLRKPSVSAQMQAYGQSSYSTQTWVRQQQMVVAHQ 600
            LGLGMDGPYERERTFGSREPKQPQPLLRKPSVSAQMQAYGQSSYSTQTWVRQQQMVVAHQ
Sbjct: 541  LGLGMDGPYERERTFGSREPKQPQPLLRKPSVSAQMQAYGQSSYSTQTWVRQQQMVVAHQ 600

Query: 601  YSFAPDGEARLVSRCPADNPGLVQAQPRVPLTPTRGTSSRVAVQRGVGSGPHPPDTQQPS 660
            YSFAPDGEARLVSRCPADNPGLVQAQPRVPLTPTRGTSSRVAVQRGVGSGPHPPDTQQPS
Sbjct: 601  YSFAPDGEARLVSRCPADNPGLVQAQPRVPLTPTRGTSSRVAVQRGVGSGPHPPDTQQPS 660

Query: 661  PSKAFKPRFPGDQVVNGAGPELSTGPSPGSPTLDIDQSIEQLNRLILELDPTFEPIPTHM 720
            PSKAFKPRFPGDQVVNGAGPELSTGPSPGSPTLDIDQSIEQLNRLILELDPTFEPIPTHM
Sbjct: 661  PSKAFKPRFPGDQVVNGAGPELSTGPSPGSPTLDIDQSIEQLNRLILELDPTFEPIPTHM 720

Query: 721  NALGSQANGSVSPDSVGGGLRASSRLPDTGEGPSRATGRQGSSAEQPLGGRLRKLSLGQY 780
            NALGSQANGSVSPDSVGGGLRASSRLPDTGEGPSRATGRQGSSAEQPLGGRLRKLSLGQY
Sbjct: 721  NALGSQANGSVSPDSVGGGLRASSRLPDTGEGPSRATGRQGSSAEQPLGGRLRKLSLGQY 780

Query: 781  DNDAGGQLPFSKCAWGKAGVDYAPNLPPFPSPADVKETMTPGYPQDLDIIDGRILSSKES 840
            DNDAGGQLPFSKCAWGKAGVDYAPNLPPFPSPADVKETMTPGYPQDLDIIDGRILSSKES
Sbjct: 781  DNDAGGQLPFSKCAWGKAGVDYAPNLPPFPSPADVKETMTPGYPQDLDIIDGRILSSKES 840

Query: 841  MCSTPAFPVSPETPYVKTALRHPPFSPPEPPLSSPASQHKGGREPRSCPETLTHAVGMSE 900
            MCSTPAFPVSPETPYVKTALRHPPFSPPEPPLSSPASQHKGGREPRSCPETLTHAVGMSE
Sbjct: 841  MCSTPAFPVSPETPYVKTALRHPPFSPPEPPLSSPASQHKGGREPRSCPETLTHAVGMSE 900

Query: 901  SPIGPKSTMLRADASSTPSFQQAFASSCTISSNGPGQRRESSSSAERQWVESSPKPMVSL 960
            SPIGPKSTMLRADASSTPSFQQAFASSCTISSNGPGQRRESSSSAERQWVESSPKPMVSL
Sbjct: 901  SPIGPKSTMLRADASSTPSFQQAFASSCTISSNGPGQRRESSSSAERQWVESSPKPMVSL 960

Query: 961  LGSGRPTGSPLSAEFSGTRKDSPVLSCFPPSELQAPFHSHELSLAEPPDSLAPPSSQAFL 1020
            LGSGRPTGSPLSAEFSGTRKDSPVLSCFPPSELQAPFHSHELSLAEPPDSLAPPSSQAFL
Sbjct: 961  LGSGRPTGSPLSAEFSGTRKDSPVLSCFPPSELQAPFHSHELSLAEPPDSLAPPSSQAFL 1020

Query: 1021 GFGTAPVGSGLPPEEDLGALLANSHGASPTPSIPLTATGAADNGFLSHNFLTVAPGHSSH 1080
            GFGTAPVGSGLPPEEDLGALLANSHGASPTPSIPLTATGAADNGFLSHNFLTVAPGHSSH
Sbjct: 1021 GFGTAPVGSGLPPEEDLGALLANSHGASPTPSIPLTATGAADNGFLSHNFLTVAPGHSSH 1080

Query: 1081 HSPGLQGQGVTLPGQPPLPEKKRASEGDRSLGSVSPSSSGFSSPHSGSTISIPFPNVLPD 1140
            HSPGLQGQGVTLPGQPPLPEKKRASEGDRSLGSVSPSSSGFSSPHSGSTISIPFPNVLPD
Sbjct: 1081 HSPGLQGQGVTLPGQPPLPEKKRASEGDRSLGSVSPSSSGFSSPHSGSTISIPFPNVLPD 1140

Query: 1141 FSKASEAASPLPDSPGDKLVIVKFVQDTSKFWYKADISREQAIAMLKDKEPGSFIVRDSH 1200
            FSKASEAASPLPDSPGDKLVIVKFVQDTSKFWYKADISREQAIAMLKDKEPGSFIVRDSH
Sbjct: 1141 FSKASEAASPLPDSPGDKLVIVKFVQDTSKFWYKADISREQAIAMLKDKEPGSFIVRDSH 1200

Query: 1201 SFRGAYGLAMKVATPPPSVLQLNKKAGDLANELVRHFLIECTPKGVRLKGCSNEPYFGSL 1260
            SFRGAYGLAMKVATPPPSVLQLNKKAGDLANELVRHFLIECTPKGVRLKGCSNEPYFGSL
Sbjct: 1201 SFRGAYGLAMKVATPPPSVLQLNKKAGDLANELVRHFLIECTPKGVRLKGCSNEPYFGSL 1260

Query: 1261 TALVCQHSITPLALPCKLLIPERDPLEEIAESSPQTAANSAAELLKQGAACNVWYLNSVE 1320
            TALVCQHSITPLALPCKLLIPERDPLEEIAESSPQTAANSAAELLKQGAACNVWYLNSVE
Sbjct: 1261 TALVCQHSITPLALPCKLLIPERDPLEEIAESSPQTAANSAAELLKQGAACNVWYLNSVE 1320

Query: 1321 MESLTGHQAIQKALSITLVQEPPPVSTVVHFKVSAQGITLTDNQRKLFFRRHYPVNSVIF 1380
            MESLTGHQAIQKALSITLVQEPPPVSTVVHFKVSAQGITLTDNQRKLFFRRHYPVNSVIF
Sbjct: 1321 MESLTGHQAIQKALSITLVQEPPPVSTVVHFKVSAQGITLTDNQRKLFFRRHYPVNSVIF 1380

Query: 1381 CALDPQDRKWIKDGPSSKVFGFVARKQGSATDNVCHLFAEHDPEQPASAIVNFVSKVMIG 1440
            CALDPQDRKWIKDGPSSKVFGFVARKQGSATDNVCHLFAEHDPEQPASAIVNFVSKVMIG
Sbjct: 1381 CALDPQDRKWIKDGPSSKVFGFVARKQGSATDNVCHLFAEHDPEQPASAIVNFVSKVMIG 1440

Query: 1441 SPKKV 1445
            SPKKV
Sbjct: 1441 SPKKV 1445


>gi|66529407 tensin [Homo sapiens]
          Length = 1735

 Score =  689 bits (1777), Expect = 0.0
 Identities = 494/1251 (39%), Positives = 647/1251 (51%), Gaps = 200/1251 (15%)

Query: 1    MEEGHGLDLTYITERIIAVSFPAGCSEESYLHNLQEVTRMLKSKHGDNYLVLNLSEKRYD 60
            ME+   LDL Y+TERIIAVSFP+  +EE++  NL+EV +MLKSKHG NYL+ NLSE+R D
Sbjct: 7    MEDSCELDLVYVTERIIAVSFPSTANEENFRSNLREVAQMLKSKHGGNYLLFNLSERRPD 66

Query: 61   LTKLNPKIMDVGWPELHAPPLDKMCTICKAQESWLNSNLQHVVVIHCRGGKGRIGVVISS 120
            +TKL+ K+++ GWP+LH P L+K+C+ICKA ++WLN++  +VVV+H +G +GRIGVVI++
Sbjct: 67   ITKLHAKVLEFGWPDLHTPALEKICSICKAMDTWLNADPHNVVVLHNKGNRGRIGVVIAA 126

Query: 121  YMHFTNVSASADQALDRFAMKKFYDDKVSALMQPSQKRYVQFLSGLLSGSVKMNASPLFL 180
            YMH++N+SASADQALDRFAMK+FY+DK+  + QPSQ+RYV + SGLLSGS+KMN  PLFL
Sbjct: 127  YMHYSNISASADQALDRFAMKRFYEDKIVPIGQPSQRRYVHYFSGLLSGSIKMNNKPLFL 186

Query: 181  HFVILHGTPNFDTGGVCRPFLKLYQAMQPVYTSGIYNVGPENPSRICIVIEPAQLLKGDV 240
            H VI+HG PNF++ G CRPFL++YQAMQPVYTSGIYN+  ++ + +CI IEP  LLKGD+
Sbjct: 187  HHVIMHGIPNFESKGGCRPFLRIYQAMQPVYTSGIYNIPGDSQTSVCITIEPGLLLKGDI 246

Query: 241  MVKCYHKKYRSATRDVIFRLQFHTGAVQGYGLVFGKEDLDNASKDDRFPDYGKVELVFSA 300
            ++KCYHKK+RS  RDVIFR+QFHT A+   G+VFGKEDLD+A KDDRFP+YGKVE VFS 
Sbjct: 247  LLKCYHKKFRSPARDVIFRVQFHTCAIHDLGVVFGKEDLDDAFKDDRFPEYGKVEFVFSY 306

Query: 301  TPEKIQGSEHLYNDHGVIVDYNTTDPLIRWDSYENLSA---DG--EVL-HTQGPVDGSLY 354
             PEKIQG EHL N   V VDYNT+DPLIRWDSY+N S    DG  EV+ HTQGP+DGSLY
Sbjct: 307  GPEKIQGMEHLENGPSVSVDYNTSDPLIRWDSYDNFSGHRDDGMEEVVGHTQGPLDGSLY 366

Query: 355  AKVRKKSSSDPGIPGGPQAIPATN-----SPDHSDHTLSVSSDSGHSTASARTDKTEERL 409
            AKV+KK S    + G   A+ AT      +P+H +HTLSVSSDSG+STAS +TDKT+E +
Sbjct: 367  AKVKKKDS----LHGSTGAVNATRPTLSATPNHVEHTLSVSSDSGNSTASTKTDKTDEPV 422

Query: 410  --APGTRRGLSAQEKAELDQLLSGFGLE-DPGSSLKEMTDARSKYSG-------TRHVVP 459
              A      LS QEK ELD+LLSGFGLE +   ++      RS+ +G        RHVVP
Sbjct: 423  PGASSATAALSPQEKRELDRLLSGFGLEREKQGAMYHTQHLRSRPAGGSAVPSSGRHVVP 482

Query: 460  AQVHVNGDAALKDRETDILDDEMPHHDLHSVDSLGTLSSSEGPQSAHLGPFTCHKSSQNS 519
            AQVHVNG A   +RETDILDDE+P+ D HS  S+GTLSS +G  +   G +        S
Sbjct: 483  AQVHVNGGALASERETDILDDELPNQDGHSAGSMGTLSSLDGVTNTSEGGY----PEALS 538

Query: 520  LLSDGFGSNVGEDPQGTLVPDLGLGMDGPYERERTFGSREPKQPQPLLRKPSVSAQMQAY 579
             L++G   +   +P          G   PYE     G        P+  +PS SAQ    
Sbjct: 539  PLTNGLDKSYPMEPMVN-------GGGYPYESASRAGPAHAGHTAPM--RPSYSAQEGLA 589

Query: 580  G-QSSYSTQTWVRQQQMVVAHQYSFAPDGEARLVSRCPADNPGLVQAQPRVPLTPTRGTS 638
            G Q       W    Q V    Y+  P G  R        +    +A+P++P  P RG S
Sbjct: 590  GYQREGPHPAW---PQPVTTSHYAHDPSGMFR--------SQSFSEAEPQLPPAPVRGGS 638

Query: 639  SRVAVQRGVGSGPHPPDTQQ---PSPSKAFKPRFPGDQVVNGAGPELSTGPSPGSPTL-- 693
            SR AVQRG+ S       QQ   P P +  +           +   L+  P P  P    
Sbjct: 639  SREAVQRGLNSWQQQQQQQQQPRPPPRQQERAHLESLVASRPSPQPLAETPIPSLPEFPR 698

Query: 694  -----DIDQSIEQLNRLILELDPTFEPIPTHMNALGSQANGSVSPDSVGGGLRASSRLPD 748
                 +I+QSIE LN L+L+L+P     P H +             SV G    +S L  
Sbjct: 699  AASQQEIEQSIETLNMLMLDLEPASAAAPLHKS------------QSVPGAWPGASPL-- 744

Query: 749  TGEGPSRATGRQGSSAEQPLGGRLRKLSLGQYDNDAGGQLPFSKCAWGKAGVDYAPNLPP 808
                           + QPL G  R+             L  S+  +  +G        P
Sbjct: 745  ---------------SSQPLSGSSRQ----------SHPLTQSRSGYIPSGHSLG---TP 776

Query: 809  FPSPADVKETMTPG-------YPQDLDIIDGRILSSKESMCSTPAF------PVSPETPY 855
             P+P    E++ PG       Y   L   +    S   +  S PAF      P  P+ P 
Sbjct: 777  EPAPRASLESVPPGRSYSPYDYQPCLAGPNQDFHSKSPASSSLPAFLPTTHSPPGPQQPP 836

Query: 856  VK-TALRHPPFSPPEPPLSSPASQHKGGREPRSCPETLTHAV----GMSESPIGPKSTML 910
                 L   P   P+   S P+   +   EP +    + H V       + P  P + + 
Sbjct: 837  ASLPGLTAQPLLSPKEATSDPSRTPE--EEPLNLEGLVAHRVAGVQAREKQPAEPPAPLR 894

Query: 911  RADASSTPSFQQAFASSCTISSNGPGQRRESSSSAERQWVESSPKPMVSLLGSGRPTGSP 970
            R  AS     Q    S    S   PG R      +  Q V       ++L   GRP    
Sbjct: 895  RRAASDG---QYENQSPEATSPRSPGVR------SPVQCVSPELALTIALNPGGRPKEPH 945

Query: 971  LSA------EFSGTRKDSPVLSCFPPSELQAPFHSHELSLAEPPDS---LAPPSSQAFLG 1021
            L +      E  GT   SP     PPS +++P       LA+ P S   L P +    L 
Sbjct: 946  LHSYKEAFEEMEGTSPSSP-----PPSGVRSP-----PGLAKTPLSALGLKPHNPADILL 995

Query: 1022 FGTAPVGSGLPPEEDLGALLA--NSHGASPTPSIPLTATG---AAD-------------- 1062
              T      + PEED G ++   +    S   S+  TA     A D              
Sbjct: 996  HPTGVTRRRIQPEEDEGKVVVRLSEEPRSYVESVARTAVAGPRAQDSEPKSFSAPATQAY 1055

Query: 1063 -------NGFLSHNFLTVAPGHSSHHSPGLQG---------------QGVTLPGQPPLPE 1100
                   NG L  +F  V+P   S  SP L                 QG   P QP L  
Sbjct: 1056 GHEIPLRNGTLGGSF--VSPSPLSTSSPILSADSTSVGSFPSGESSDQGPRTPTQPLLES 1113

Query: 1101 KKRASEGDRSLGSVSPSSS-GFSSPHSGSTISIPFPNVLPDFSKASEAASP 1150
              R+     SLG  SPS+   + S     T+   + +  PD+S    ++SP
Sbjct: 1114 GFRSG----SLGQPSPSAQRNYQSSSPLPTVGSSYSS--PDYSLQHFSSSP 1158



 Score =  464 bits (1193), Expect = e-130
 Identities = 301/664 (45%), Positives = 376/664 (56%), Gaps = 65/664 (9%)

Query: 831  DGRILSSKESMCSTPAFPVSPETPYVKTALRHPPFSPPEPPLS----SPASQHKGGREPR 886
            D   + S  S  S+   P +P  P +++  R      P P       S +     G    
Sbjct: 1086 DSTSVGSFPSGESSDQGPRTPTQPLLESGFRSGSLGQPSPSAQRNYQSSSPLPTVGSSYS 1145

Query: 887  SCPETLTHAVGMSESPIGPKSTMLRADA-SSTPSFQQAFASSCTISSNGPGQRRESSSSA 945
            S   +L H     ES    + ++        +P  +     + T  S G G R  + S A
Sbjct: 1146 SPDYSLQHFSSSPESQARAQFSVAGVHTVPGSPQARHRTVGTNTPPSPGFGWRAINPSMA 1205

Query: 946  ERQWVESSPKPMVSLLGSG---RPTGSPLSAEFSGTRKDSPVLSCFPPSELQAPFHSHEL 1002
                   S   M+   G+G       SP S+  + T   SP L   P    Q     +++
Sbjct: 1206 APSSPSLSHHQMMGPPGTGFHGSTVSSPQSS--AATTPGSPSLCRHPAGVYQVSGLHNKV 1263

Query: 1003 SLAEPPDSLA--PPSSQAFLGFGTAPVGSGLPPEEDLGALLANSHGASPTPSIPLTATGA 1060
            +      SL   P + Q  L  G        P    LG  L  S   S  P  P      
Sbjct: 1264 ATTPGSPSLGRHPGAHQGNLASGLHSNAIASPGSPSLGRHLGGS--GSVVPGSPCLDRHV 1321

Query: 1061 ADNGFLSH-------NFLTVAPGHSSHHSPGLQGQGVTLPG------------------- 1094
            A  G+ +        +  + A G+ +  +P         PG                   
Sbjct: 1322 AYGGYSTPEDRRPTLSRQSSASGYQAPSTPSFPVSPAYYPGLSSPATSPSPDSAAFRQGS 1381

Query: 1095 -QPPLPEKKRASEGDRSLGSV-----------SPSSSGFSSPHSGSTISIPFPNVLPDFS 1142
              P LPEK+R S GDR+ GS+           SP +SG SSP  GST+S  F + LPDFS
Sbjct: 1382 PTPALPEKRRMSVGDRA-GSLPNYATINGKVSSPVASGMSSPSGGSTVS--FSHTLPDFS 1438

Query: 1143 KASEAASPLPDSPGDKLVIVKFVQDTSKFWYKADISREQAIAMLKDKEPGSFIVRDSHSF 1202
            K S     +PD+  +    VKFVQDTSK+WYK +ISREQAIA+LKD+EPG+FI+RDSHSF
Sbjct: 1439 KYS-----MPDNSPETRAKVKFVQDTSKYWYKPEISREQAIALLKDQEPGAFIIRDSHSF 1493

Query: 1203 RGAYGLAMKVATPPPSVLQLNKKAGDLANELVRHFLIECTPKGVRLKGCSNEPYFGSLTA 1262
            RGAYGLAMKV++PPP+++Q NKK GD+ +ELVRHFLIE  P+GV+LKGC NEP FGSL+A
Sbjct: 1494 RGAYGLAMKVSSPPPTIMQQNKK-GDMTHELVRHFLIETGPRGVKLKGCPNEPNFGSLSA 1552

Query: 1263 LVCQHSITPLALPCKLLIPERDPLEEIAESSPQTAANSAAELLKQGAACNVWYLNSVEME 1322
            LV QHSI PLALPCKL+IP RDP +E  +SS    ANS A+LLKQGAACNV ++NSV+ME
Sbjct: 1553 LVYQHSIIPLALPCKLVIPNRDPTDESKDSSGP--ANSTADLLKQGAACNVLFVNSVDME 1610

Query: 1323 SLTGHQAIQKALSITLVQEPPPVSTVVHFKVSAQGITLTDNQRKLFFRRHYPVNSVIFCA 1382
            SLTG QAI KA S TL  +P P +T+VHFKVSAQGITLTDNQRKLFFRRHYP+N+V FC 
Sbjct: 1611 SLTGPQAISKATSETLAADPTPAATIVHFKVSAQGITLTDNQRKLFFRRHYPLNTVTFCD 1670

Query: 1383 LDPQDRKWIK--DGPSSKVFGFVARKQGSATDNVCHLFAEHDPEQPASAIVNFVSKVMIG 1440
            LDPQ+RKW+K   G  +K+FGFVARKQGS TDN CHLFAE DP QPASAIVNFVSKVM+ 
Sbjct: 1671 LDPQERKWMKTEGGAPAKLFGFVARKQGSTTDNACHLFAELDPNQPASAIVNFVSKVMLN 1730

Query: 1441 SPKK 1444
            + +K
Sbjct: 1731 AGQK 1734


>gi|38787970 tensin like C1 domain containing phosphatase isoform 3
           [Homo sapiens]
          Length = 1285

 Score =  461 bits (1185), Expect = e-129
 Identities = 232/444 (52%), Positives = 310/444 (69%), Gaps = 20/444 (4%)

Query: 1   MEEGHGLDLTYITERIIAVSFPAGCSEESYLHNLQEVTRMLKSKHGDNYLVLNLSEKRYD 60
           ME    LDLTY+TERI+A +FPA   E+ +  +L+E+  +L+SKH D YL+ NLSEKR+D
Sbjct: 1   MERRWDLDLTYVTERILAAAFPARPDEQRHRGHLRELAHVLQSKHRDKYLLFNLSEKRHD 60

Query: 61  LTKLNPKIMDVGWPELHAPPLDKMCTICKAQESWLNSNLQHVVVIHCRGGKGRIGVVISS 120
           LT+LNPK+ D GWPELHAPPLDK+C+ICKA E+WL+++ QHVVV++C+G KG++GV++S+
Sbjct: 61  LTRLNPKVQDFGWPELHAPPLDKLCSICKAMETWLSADPQHVVVLYCKGNKGKLGVIVSA 120

Query: 121 YMHFTNVSASADQALDRFAMKKFYDDKVSALMQPSQKRYVQFLSGLLSGSVKMNASPLFL 180
           YMH++ +SA ADQAL    M+KF +DKV+  +QPSQ+RY+ + SGLLSGS++MN+SPLFL
Sbjct: 121 YMHYSKISAGADQALATLTMRKFCEDKVATELQPSQRRYISYFSGLLSGSIRMNSSPLFL 180

Query: 181 HFVILHGTPNFDTGGVCRPFLKLYQAMQPVYTSGIYNVGPENPSRICIVIEPAQLLKGDV 240
           H+V++   P F+ G   +PFLK+YQ+MQ VYTSG+Y++    P ++CI +EPA LLKGDV
Sbjct: 181 HYVLIPMLPAFEPGTGFQPFLKIYQSMQLVYTSGVYHIAGPGPQQLCISLEPALLLKGDV 240

Query: 241 MVKCYHKKYRSATRDVIFRLQFHTGAVQGYGLVFGKEDLDNASKDDRFPDYGKVELVFSA 300
           MV CYHK  R   R ++FR+QFHT  + G  L F K+ LD A  D+RFP    VE VFS+
Sbjct: 241 MVTCYHKGGRGTDRTLVFRVQFHTCTIHGPQLTFPKDQLDEAWTDERFPFQASVEFVFSS 300

Query: 301 TPEKIQGSEHLYNDHGVIVDYNTTDPLIRWDSYENL------SADGEVLHTQGPVDGSLY 354
           +PEKI+GS    ND  V VDYNTT+P +RWDSYEN       S DG + HT+GP+DGS Y
Sbjct: 301 SPEKIKGSTP-RNDPSVSVDYNTTEPAVRWDSYENFNQHHEDSVDGSLTHTRGPLDGSPY 359

Query: 355 AKVRKKSSSDPGIPGGPQAIPATNSPDHSDHTLSVSSDSGHSTASARTDKTEERLAPGTR 414
           A+V++     P  P  P+  P           LSVSSDSGHS+        E   +PG R
Sbjct: 360 AQVQRPPRQTPPAP-SPEPPPPP--------MLSVSSDSGHSSTLTTEPAAE---SPG-R 406

Query: 415 RGLSAQEKAELDQLLSGFGLEDPG 438
              +A E+ ELD+LL G G+   G
Sbjct: 407 PPPTAAERQELDRLLGGCGVASGG 430



 Score =  412 bits (1058), Expect = e-114
 Identities = 265/594 (44%), Positives = 337/594 (56%), Gaps = 67/594 (11%)

Query: 875  PASQHKGGREPRSCPETLTHAVGMSESPIGPKSTMLRADASSTPSFQQAFASSCT-ISSN 933
            P   H     P +  E+L   V   E P G  ST+ R+   +  S     +   T + ++
Sbjct: 734  PLPGHLASAGPLASAESL-EPVSWREGPSG-HSTLPRSPRDAPCSASSELSGPSTPLHTS 791

Query: 934  GPGQRRESSSSAERQWVESSPK---------PMVSLLGSGRPTGSPLSAEFSGTRKDSPV 984
             P Q +ES+   + +   S+P          P VS  G+G+    P S         SPV
Sbjct: 792  SPVQGKESTRRQDTRSPTSAPTQRLSPGEALPPVSQAGTGKAPELP-SGSGPEPLAPSPV 850

Query: 985  LSCFPPS-------ELQAPFHSHELSLAEPPDSLAPPSS----QAFLGFGTAPVGSGLPP 1033
               FPPS       E     HS   S   P  +  P       Q   G   +P GS L P
Sbjct: 851  SPTFPPSSPSDWPQERSPGGHSDGASPRSPVPTTLPGLRHAPWQGPRGPPDSPDGSPLTP 910

Query: 1034 -EEDLGALLANSHG--ASPTPSIPLTATGAADNGFLSHNFLTVAPGHSSHHSPGLQGQGV 1090
                +  L+A+     +SPTP+ PL A                     S+ + GL     
Sbjct: 911  VPSQMPWLVASPEPPQSSPTPAFPLAA---------------------SYDTNGLS---- 945

Query: 1091 TLPGQPPLPEKKRASEGDRSLGSVSPSSSGFSSPHSGSTISIPFPNVLPDFSKASEAASP 1150
                QPPLPEK+      +  G   P  +  SSP  G +  + F  +L D +       P
Sbjct: 946  ----QPPLPEKRHLPGPGQQPGPWGPEQA--SSPARGISHHVTFAPLLSD-NVPQTPEPP 998

Query: 1151 LPDSPGDKLVIVKFVQDTSKFWYKADISREQAIAMLKDKEPGSFIVRDSHSFRGAYGLAM 1210
              +S  +    VKFVQDTSKFWYK  +SR+QAIA+LKDK+PG+F++RDSHSF+GAYGLA+
Sbjct: 999  TQESQSN----VKFVQDTSKFWYKPHLSRDQAIALLKDKDPGAFLIRDSHSFQGAYGLAL 1054

Query: 1211 KVATPPPSVLQLNKKAGDLANELVRHFLIECTPKGVRLKGCSNEPYFGSLTALVCQHSIT 1270
            KVATPPPS        GD   +LVRHFLIE  PKGV++KGC +EPYFGSL+ALV QHSI+
Sbjct: 1055 KVATPPPSAQPWK---GDPVEQLVRHFLIETGPKGVKIKGCPSEPYFGSLSALVSQHSIS 1111

Query: 1271 PLALPCKLLIPERDPLEEIAESSPQTAANSAAELLKQGAACNVWYLNSVEMESLTGHQAI 1330
            P++LPC L IP +DPLEE  E+   T  ++AA+LL+QGAAC+V YL SVE ESLTG QA+
Sbjct: 1112 PISLPCCLRIPSKDPLEETPEAPVPTNMSTAADLLRQGAACSVLYLTSVETESLTGPQAV 1171

Query: 1331 QKALSITLVQEPPPVSTVVHFKVSAQGITLTDNQRKLFFRRHYPVNSVIFCALDPQDRKW 1390
             +A S  L   P P   VVHFKVSAQGITLTDNQRKLFFRRHYPVNS+ F + DPQDR+W
Sbjct: 1172 ARASSAALSCSPRPTPAVVHFKVSAQGITLTDNQRKLFFRRHYPVNSITFSSTDPQDRRW 1231

Query: 1391 IK-DGPSSKVFGFVARKQGSATDNVCHLFAEHDPEQPASAIVNFVSKVMIGSPK 1443
               DG +SK+FGFVA+K GS  +NVCHLFAE DP+QPA AIV F++KV++G  K
Sbjct: 1232 TNPDGTTSKIFGFVAKKPGSPWENVCHLFAELDPDQPAGAIVTFITKVLLGQRK 1285



 Score = 37.0 bits (84), Expect = 0.14
 Identities = 57/210 (27%), Positives = 79/210 (37%), Gaps = 31/210 (14%)

Query: 687 SPGSPTLDIDQSIEQLNRLILELDPTFE-----PIPTHMNALGSQANG-SVSPDSVGGGL 740
           SPGSP         Q  +L  E+ PT E     P+P H+ + G  A+  S+ P S   G 
Sbjct: 708 SPGSPPYP------QSRKLSYEI-PTEEGGDRYPLPGHLASAGPLASAESLEPVSWREGP 760

Query: 741 RASSRLPDTGEGPSRATGRQGSSAEQPLGGRLR---KLSLGQYDNDAGGQLPFSKCAWGK 797
              S LP +      +   + S    PL        K S  + D  +    P  + + G+
Sbjct: 761 SGHSTLPRSPRDAPCSASSELSGPSTPLHTSSPVQGKESTRRQDTRSPTSAPTQRLSPGE 820

Query: 798 A-------GVDYAPNLP----PFP-SPADVKETMTPGYPQDLDIIDGRILSSKESMCSTP 845
           A       G   AP LP    P P +P+ V  T  P  P D             S  ++P
Sbjct: 821 ALPPVSQAGTGKAPELPSGSGPEPLAPSPVSPTFPPSSPSDWP---QERSPGGHSDGASP 877

Query: 846 AFPVSPETPYVKTALRHPPFSPPEPPLSSP 875
             PV    P ++ A    P  PP+ P  SP
Sbjct: 878 RSPVPTTLPGLRHAPWQGPRGPPDSPDGSP 907



 Score = 35.4 bits (80), Expect = 0.40
 Identities = 46/179 (25%), Positives = 63/179 (35%), Gaps = 20/179 (11%)

Query: 530 GEDPQGTLVPDLGLGMDGPYERERTFGSREP-KQPQPLLRKPSVSAQMQAYGQ-----SS 583
           G  P     P  G G   P       GS  P   P P  RK S     +  G        
Sbjct: 679 GRVPHSCGSPGEGRGYPSPGAHSPRAGSISPGSPPYPQSRKLSYEIPTEEGGDRYPLPGH 738

Query: 584 YSTQTWVRQQQMVVAHQYSFAPDGEARLVSRCPADNPGLVQAQPRVPLTPTRGTS---SR 640
            ++   +   + +    +   P G + L  R P D P    ++   P TP   +S    +
Sbjct: 739 LASAGPLASAESLEPVSWREGPSGHSTL-PRSPRDAPCSASSELSGPSTPLHTSSPVQGK 797

Query: 641 VAVQRGVGSGPHPPDTQQPSPSKAFKPRFPGDQVVNGAGPELSTG-------PSPGSPT 692
            + +R     P    TQ+ SP +A     P  Q   G  PEL +G       PSP SPT
Sbjct: 798 ESTRRQDTRSPTSAPTQRLSPGEALP---PVSQAGTGKAPELPSGSGPEPLAPSPVSPT 853


>gi|38787957 tensin like C1 domain containing phosphatase isoform 2
           [Homo sapiens]
          Length = 1409

 Score =  461 bits (1185), Expect = e-129
 Identities = 232/444 (52%), Positives = 310/444 (69%), Gaps = 20/444 (4%)

Query: 1   MEEGHGLDLTYITERIIAVSFPAGCSEESYLHNLQEVTRMLKSKHGDNYLVLNLSEKRYD 60
           ME    LDLTY+TERI+A +FPA   E+ +  +L+E+  +L+SKH D YL+ NLSEKR+D
Sbjct: 125 MERRWDLDLTYVTERILAAAFPARPDEQRHRGHLRELAHVLQSKHRDKYLLFNLSEKRHD 184

Query: 61  LTKLNPKIMDVGWPELHAPPLDKMCTICKAQESWLNSNLQHVVVIHCRGGKGRIGVVISS 120
           LT+LNPK+ D GWPELHAPPLDK+C+ICKA E+WL+++ QHVVV++C+G KG++GV++S+
Sbjct: 185 LTRLNPKVQDFGWPELHAPPLDKLCSICKAMETWLSADPQHVVVLYCKGNKGKLGVIVSA 244

Query: 121 YMHFTNVSASADQALDRFAMKKFYDDKVSALMQPSQKRYVQFLSGLLSGSVKMNASPLFL 180
           YMH++ +SA ADQAL    M+KF +DKV+  +QPSQ+RY+ + SGLLSGS++MN+SPLFL
Sbjct: 245 YMHYSKISAGADQALATLTMRKFCEDKVATELQPSQRRYISYFSGLLSGSIRMNSSPLFL 304

Query: 181 HFVILHGTPNFDTGGVCRPFLKLYQAMQPVYTSGIYNVGPENPSRICIVIEPAQLLKGDV 240
           H+V++   P F+ G   +PFLK+YQ+MQ VYTSG+Y++    P ++CI +EPA LLKGDV
Sbjct: 305 HYVLIPMLPAFEPGTGFQPFLKIYQSMQLVYTSGVYHIAGPGPQQLCISLEPALLLKGDV 364

Query: 241 MVKCYHKKYRSATRDVIFRLQFHTGAVQGYGLVFGKEDLDNASKDDRFPDYGKVELVFSA 300
           MV CYHK  R   R ++FR+QFHT  + G  L F K+ LD A  D+RFP    VE VFS+
Sbjct: 365 MVTCYHKGGRGTDRTLVFRVQFHTCTIHGPQLTFPKDQLDEAWTDERFPFQASVEFVFSS 424

Query: 301 TPEKIQGSEHLYNDHGVIVDYNTTDPLIRWDSYENL------SADGEVLHTQGPVDGSLY 354
           +PEKI+GS    ND  V VDYNTT+P +RWDSYEN       S DG + HT+GP+DGS Y
Sbjct: 425 SPEKIKGSTP-RNDPSVSVDYNTTEPAVRWDSYENFNQHHEDSVDGSLTHTRGPLDGSPY 483

Query: 355 AKVRKKSSSDPGIPGGPQAIPATNSPDHSDHTLSVSSDSGHSTASARTDKTEERLAPGTR 414
           A+V++     P  P  P+  P           LSVSSDSGHS+        E   +PG R
Sbjct: 484 AQVQRPPRQTPPAP-SPEPPPPP--------MLSVSSDSGHSSTLTTEPAAE---SPG-R 530

Query: 415 RGLSAQEKAELDQLLSGFGLEDPG 438
              +A E+ ELD+LL G G+   G
Sbjct: 531 PPPTAAERQELDRLLGGCGVASGG 554



 Score =  412 bits (1058), Expect = e-114
 Identities = 265/594 (44%), Positives = 337/594 (56%), Gaps = 67/594 (11%)

Query: 875  PASQHKGGREPRSCPETLTHAVGMSESPIGPKSTMLRADASSTPSFQQAFASSCT-ISSN 933
            P   H     P +  E+L   V   E P G  ST+ R+   +  S     +   T + ++
Sbjct: 858  PLPGHLASAGPLASAESL-EPVSWREGPSG-HSTLPRSPRDAPCSASSELSGPSTPLHTS 915

Query: 934  GPGQRRESSSSAERQWVESSPK---------PMVSLLGSGRPTGSPLSAEFSGTRKDSPV 984
             P Q +ES+   + +   S+P          P VS  G+G+    P S         SPV
Sbjct: 916  SPVQGKESTRRQDTRSPTSAPTQRLSPGEALPPVSQAGTGKAPELP-SGSGPEPLAPSPV 974

Query: 985  LSCFPPS-------ELQAPFHSHELSLAEPPDSLAPPSS----QAFLGFGTAPVGSGLPP 1033
               FPPS       E     HS   S   P  +  P       Q   G   +P GS L P
Sbjct: 975  SPTFPPSSPSDWPQERSPGGHSDGASPRSPVPTTLPGLRHAPWQGPRGPPDSPDGSPLTP 1034

Query: 1034 -EEDLGALLANSHG--ASPTPSIPLTATGAADNGFLSHNFLTVAPGHSSHHSPGLQGQGV 1090
                +  L+A+     +SPTP+ PL A                     S+ + GL     
Sbjct: 1035 VPSQMPWLVASPEPPQSSPTPAFPLAA---------------------SYDTNGLS---- 1069

Query: 1091 TLPGQPPLPEKKRASEGDRSLGSVSPSSSGFSSPHSGSTISIPFPNVLPDFSKASEAASP 1150
                QPPLPEK+      +  G   P  +  SSP  G +  + F  +L D +       P
Sbjct: 1070 ----QPPLPEKRHLPGPGQQPGPWGPEQA--SSPARGISHHVTFAPLLSD-NVPQTPEPP 1122

Query: 1151 LPDSPGDKLVIVKFVQDTSKFWYKADISREQAIAMLKDKEPGSFIVRDSHSFRGAYGLAM 1210
              +S  +    VKFVQDTSKFWYK  +SR+QAIA+LKDK+PG+F++RDSHSF+GAYGLA+
Sbjct: 1123 TQESQSN----VKFVQDTSKFWYKPHLSRDQAIALLKDKDPGAFLIRDSHSFQGAYGLAL 1178

Query: 1211 KVATPPPSVLQLNKKAGDLANELVRHFLIECTPKGVRLKGCSNEPYFGSLTALVCQHSIT 1270
            KVATPPPS        GD   +LVRHFLIE  PKGV++KGC +EPYFGSL+ALV QHSI+
Sbjct: 1179 KVATPPPSAQPWK---GDPVEQLVRHFLIETGPKGVKIKGCPSEPYFGSLSALVSQHSIS 1235

Query: 1271 PLALPCKLLIPERDPLEEIAESSPQTAANSAAELLKQGAACNVWYLNSVEMESLTGHQAI 1330
            P++LPC L IP +DPLEE  E+   T  ++AA+LL+QGAAC+V YL SVE ESLTG QA+
Sbjct: 1236 PISLPCCLRIPSKDPLEETPEAPVPTNMSTAADLLRQGAACSVLYLTSVETESLTGPQAV 1295

Query: 1331 QKALSITLVQEPPPVSTVVHFKVSAQGITLTDNQRKLFFRRHYPVNSVIFCALDPQDRKW 1390
             +A S  L   P P   VVHFKVSAQGITLTDNQRKLFFRRHYPVNS+ F + DPQDR+W
Sbjct: 1296 ARASSAALSCSPRPTPAVVHFKVSAQGITLTDNQRKLFFRRHYPVNSITFSSTDPQDRRW 1355

Query: 1391 IK-DGPSSKVFGFVARKQGSATDNVCHLFAEHDPEQPASAIVNFVSKVMIGSPK 1443
               DG +SK+FGFVA+K GS  +NVCHLFAE DP+QPA AIV F++KV++G  K
Sbjct: 1356 TNPDGTTSKIFGFVAKKPGSPWENVCHLFAELDPDQPAGAIVTFITKVLLGQRK 1409



 Score = 37.0 bits (84), Expect = 0.14
 Identities = 57/210 (27%), Positives = 79/210 (37%), Gaps = 31/210 (14%)

Query: 687  SPGSPTLDIDQSIEQLNRLILELDPTFE-----PIPTHMNALGSQANG-SVSPDSVGGGL 740
            SPGSP         Q  +L  E+ PT E     P+P H+ + G  A+  S+ P S   G 
Sbjct: 832  SPGSPPYP------QSRKLSYEI-PTEEGGDRYPLPGHLASAGPLASAESLEPVSWREGP 884

Query: 741  RASSRLPDTGEGPSRATGRQGSSAEQPLGGRLR---KLSLGQYDNDAGGQLPFSKCAWGK 797
               S LP +      +   + S    PL        K S  + D  +    P  + + G+
Sbjct: 885  SGHSTLPRSPRDAPCSASSELSGPSTPLHTSSPVQGKESTRRQDTRSPTSAPTQRLSPGE 944

Query: 798  A-------GVDYAPNLP----PFP-SPADVKETMTPGYPQDLDIIDGRILSSKESMCSTP 845
            A       G   AP LP    P P +P+ V  T  P  P D             S  ++P
Sbjct: 945  ALPPVSQAGTGKAPELPSGSGPEPLAPSPVSPTFPPSSPSDWP---QERSPGGHSDGASP 1001

Query: 846  AFPVSPETPYVKTALRHPPFSPPEPPLSSP 875
              PV    P ++ A    P  PP+ P  SP
Sbjct: 1002 RSPVPTTLPGLRHAPWQGPRGPPDSPDGSP 1031



 Score = 35.4 bits (80), Expect = 0.40
 Identities = 46/179 (25%), Positives = 63/179 (35%), Gaps = 20/179 (11%)

Query: 530 GEDPQGTLVPDLGLGMDGPYERERTFGSREP-KQPQPLLRKPSVSAQMQAYGQ-----SS 583
           G  P     P  G G   P       GS  P   P P  RK S     +  G        
Sbjct: 803 GRVPHSCGSPGEGRGYPSPGAHSPRAGSISPGSPPYPQSRKLSYEIPTEEGGDRYPLPGH 862

Query: 584 YSTQTWVRQQQMVVAHQYSFAPDGEARLVSRCPADNPGLVQAQPRVPLTPTRGTS---SR 640
            ++   +   + +    +   P G + L  R P D P    ++   P TP   +S    +
Sbjct: 863 LASAGPLASAESLEPVSWREGPSGHSTL-PRSPRDAPCSASSELSGPSTPLHTSSPVQGK 921

Query: 641 VAVQRGVGSGPHPPDTQQPSPSKAFKPRFPGDQVVNGAGPELSTG-------PSPGSPT 692
            + +R     P    TQ+ SP +A     P  Q   G  PEL +G       PSP SPT
Sbjct: 922 ESTRRQDTRSPTSAPTQRLSPGEALP---PVSQAGTGKAPELPSGSGPEPLAPSPVSPT 977


>gi|38787941 tensin like C1 domain containing phosphatase isoform 1
           [Homo sapiens]
          Length = 1419

 Score =  461 bits (1185), Expect = e-129
 Identities = 232/444 (52%), Positives = 310/444 (69%), Gaps = 20/444 (4%)

Query: 1   MEEGHGLDLTYITERIIAVSFPAGCSEESYLHNLQEVTRMLKSKHGDNYLVLNLSEKRYD 60
           ME    LDLTY+TERI+A +FPA   E+ +  +L+E+  +L+SKH D YL+ NLSEKR+D
Sbjct: 135 MERRWDLDLTYVTERILAAAFPARPDEQRHRGHLRELAHVLQSKHRDKYLLFNLSEKRHD 194

Query: 61  LTKLNPKIMDVGWPELHAPPLDKMCTICKAQESWLNSNLQHVVVIHCRGGKGRIGVVISS 120
           LT+LNPK+ D GWPELHAPPLDK+C+ICKA E+WL+++ QHVVV++C+G KG++GV++S+
Sbjct: 195 LTRLNPKVQDFGWPELHAPPLDKLCSICKAMETWLSADPQHVVVLYCKGNKGKLGVIVSA 254

Query: 121 YMHFTNVSASADQALDRFAMKKFYDDKVSALMQPSQKRYVQFLSGLLSGSVKMNASPLFL 180
           YMH++ +SA ADQAL    M+KF +DKV+  +QPSQ+RY+ + SGLLSGS++MN+SPLFL
Sbjct: 255 YMHYSKISAGADQALATLTMRKFCEDKVATELQPSQRRYISYFSGLLSGSIRMNSSPLFL 314

Query: 181 HFVILHGTPNFDTGGVCRPFLKLYQAMQPVYTSGIYNVGPENPSRICIVIEPAQLLKGDV 240
           H+V++   P F+ G   +PFLK+YQ+MQ VYTSG+Y++    P ++CI +EPA LLKGDV
Sbjct: 315 HYVLIPMLPAFEPGTGFQPFLKIYQSMQLVYTSGVYHIAGPGPQQLCISLEPALLLKGDV 374

Query: 241 MVKCYHKKYRSATRDVIFRLQFHTGAVQGYGLVFGKEDLDNASKDDRFPDYGKVELVFSA 300
           MV CYHK  R   R ++FR+QFHT  + G  L F K+ LD A  D+RFP    VE VFS+
Sbjct: 375 MVTCYHKGGRGTDRTLVFRVQFHTCTIHGPQLTFPKDQLDEAWTDERFPFQASVEFVFSS 434

Query: 301 TPEKIQGSEHLYNDHGVIVDYNTTDPLIRWDSYENL------SADGEVLHTQGPVDGSLY 354
           +PEKI+GS    ND  V VDYNTT+P +RWDSYEN       S DG + HT+GP+DGS Y
Sbjct: 435 SPEKIKGSTP-RNDPSVSVDYNTTEPAVRWDSYENFNQHHEDSVDGSLTHTRGPLDGSPY 493

Query: 355 AKVRKKSSSDPGIPGGPQAIPATNSPDHSDHTLSVSSDSGHSTASARTDKTEERLAPGTR 414
           A+V++     P  P  P+  P           LSVSSDSGHS+        E   +PG R
Sbjct: 494 AQVQRPPRQTPPAP-SPEPPPPP--------MLSVSSDSGHSSTLTTEPAAE---SPG-R 540

Query: 415 RGLSAQEKAELDQLLSGFGLEDPG 438
              +A E+ ELD+LL G G+   G
Sbjct: 541 PPPTAAERQELDRLLGGCGVASGG 564



 Score =  412 bits (1058), Expect = e-114
 Identities = 265/594 (44%), Positives = 337/594 (56%), Gaps = 67/594 (11%)

Query: 875  PASQHKGGREPRSCPETLTHAVGMSESPIGPKSTMLRADASSTPSFQQAFASSCT-ISSN 933
            P   H     P +  E+L   V   E P G  ST+ R+   +  S     +   T + ++
Sbjct: 868  PLPGHLASAGPLASAESL-EPVSWREGPSG-HSTLPRSPRDAPCSASSELSGPSTPLHTS 925

Query: 934  GPGQRRESSSSAERQWVESSPK---------PMVSLLGSGRPTGSPLSAEFSGTRKDSPV 984
             P Q +ES+   + +   S+P          P VS  G+G+    P S         SPV
Sbjct: 926  SPVQGKESTRRQDTRSPTSAPTQRLSPGEALPPVSQAGTGKAPELP-SGSGPEPLAPSPV 984

Query: 985  LSCFPPS-------ELQAPFHSHELSLAEPPDSLAPPSS----QAFLGFGTAPVGSGLPP 1033
               FPPS       E     HS   S   P  +  P       Q   G   +P GS L P
Sbjct: 985  SPTFPPSSPSDWPQERSPGGHSDGASPRSPVPTTLPGLRHAPWQGPRGPPDSPDGSPLTP 1044

Query: 1034 -EEDLGALLANSHG--ASPTPSIPLTATGAADNGFLSHNFLTVAPGHSSHHSPGLQGQGV 1090
                +  L+A+     +SPTP+ PL A                     S+ + GL     
Sbjct: 1045 VPSQMPWLVASPEPPQSSPTPAFPLAA---------------------SYDTNGLS---- 1079

Query: 1091 TLPGQPPLPEKKRASEGDRSLGSVSPSSSGFSSPHSGSTISIPFPNVLPDFSKASEAASP 1150
                QPPLPEK+      +  G   P  +  SSP  G +  + F  +L D +       P
Sbjct: 1080 ----QPPLPEKRHLPGPGQQPGPWGPEQA--SSPARGISHHVTFAPLLSD-NVPQTPEPP 1132

Query: 1151 LPDSPGDKLVIVKFVQDTSKFWYKADISREQAIAMLKDKEPGSFIVRDSHSFRGAYGLAM 1210
              +S  +    VKFVQDTSKFWYK  +SR+QAIA+LKDK+PG+F++RDSHSF+GAYGLA+
Sbjct: 1133 TQESQSN----VKFVQDTSKFWYKPHLSRDQAIALLKDKDPGAFLIRDSHSFQGAYGLAL 1188

Query: 1211 KVATPPPSVLQLNKKAGDLANELVRHFLIECTPKGVRLKGCSNEPYFGSLTALVCQHSIT 1270
            KVATPPPS        GD   +LVRHFLIE  PKGV++KGC +EPYFGSL+ALV QHSI+
Sbjct: 1189 KVATPPPSAQPWK---GDPVEQLVRHFLIETGPKGVKIKGCPSEPYFGSLSALVSQHSIS 1245

Query: 1271 PLALPCKLLIPERDPLEEIAESSPQTAANSAAELLKQGAACNVWYLNSVEMESLTGHQAI 1330
            P++LPC L IP +DPLEE  E+   T  ++AA+LL+QGAAC+V YL SVE ESLTG QA+
Sbjct: 1246 PISLPCCLRIPSKDPLEETPEAPVPTNMSTAADLLRQGAACSVLYLTSVETESLTGPQAV 1305

Query: 1331 QKALSITLVQEPPPVSTVVHFKVSAQGITLTDNQRKLFFRRHYPVNSVIFCALDPQDRKW 1390
             +A S  L   P P   VVHFKVSAQGITLTDNQRKLFFRRHYPVNS+ F + DPQDR+W
Sbjct: 1306 ARASSAALSCSPRPTPAVVHFKVSAQGITLTDNQRKLFFRRHYPVNSITFSSTDPQDRRW 1365

Query: 1391 IK-DGPSSKVFGFVARKQGSATDNVCHLFAEHDPEQPASAIVNFVSKVMIGSPK 1443
               DG +SK+FGFVA+K GS  +NVCHLFAE DP+QPA AIV F++KV++G  K
Sbjct: 1366 TNPDGTTSKIFGFVAKKPGSPWENVCHLFAELDPDQPAGAIVTFITKVLLGQRK 1419



 Score = 37.0 bits (84), Expect = 0.14
 Identities = 57/210 (27%), Positives = 79/210 (37%), Gaps = 31/210 (14%)

Query: 687  SPGSPTLDIDQSIEQLNRLILELDPTFE-----PIPTHMNALGSQANG-SVSPDSVGGGL 740
            SPGSP         Q  +L  E+ PT E     P+P H+ + G  A+  S+ P S   G 
Sbjct: 842  SPGSPPYP------QSRKLSYEI-PTEEGGDRYPLPGHLASAGPLASAESLEPVSWREGP 894

Query: 741  RASSRLPDTGEGPSRATGRQGSSAEQPLGGRLR---KLSLGQYDNDAGGQLPFSKCAWGK 797
               S LP +      +   + S    PL        K S  + D  +    P  + + G+
Sbjct: 895  SGHSTLPRSPRDAPCSASSELSGPSTPLHTSSPVQGKESTRRQDTRSPTSAPTQRLSPGE 954

Query: 798  A-------GVDYAPNLP----PFP-SPADVKETMTPGYPQDLDIIDGRILSSKESMCSTP 845
            A       G   AP LP    P P +P+ V  T  P  P D             S  ++P
Sbjct: 955  ALPPVSQAGTGKAPELPSGSGPEPLAPSPVSPTFPPSSPSDWP---QERSPGGHSDGASP 1011

Query: 846  AFPVSPETPYVKTALRHPPFSPPEPPLSSP 875
              PV    P ++ A    P  PP+ P  SP
Sbjct: 1012 RSPVPTTLPGLRHAPWQGPRGPPDSPDGSP 1041



 Score = 35.4 bits (80), Expect = 0.40
 Identities = 46/179 (25%), Positives = 63/179 (35%), Gaps = 20/179 (11%)

Query: 530 GEDPQGTLVPDLGLGMDGPYERERTFGSREP-KQPQPLLRKPSVSAQMQAYGQ-----SS 583
           G  P     P  G G   P       GS  P   P P  RK S     +  G        
Sbjct: 813 GRVPHSCGSPGEGRGYPSPGAHSPRAGSISPGSPPYPQSRKLSYEIPTEEGGDRYPLPGH 872

Query: 584 YSTQTWVRQQQMVVAHQYSFAPDGEARLVSRCPADNPGLVQAQPRVPLTPTRGTS---SR 640
            ++   +   + +    +   P G + L  R P D P    ++   P TP   +S    +
Sbjct: 873 LASAGPLASAESLEPVSWREGPSGHSTL-PRSPRDAPCSASSELSGPSTPLHTSSPVQGK 931

Query: 641 VAVQRGVGSGPHPPDTQQPSPSKAFKPRFPGDQVVNGAGPELSTG-------PSPGSPT 692
            + +R     P    TQ+ SP +A     P  Q   G  PEL +G       PSP SPT
Sbjct: 932 ESTRRQDTRSPTSAPTQRLSPGEALP---PVSQAGTGKAPELPSGSGPEPLAPSPVSPT 987


>gi|157738639 tensin 4 [Homo sapiens]
          Length = 715

 Score =  319 bits (817), Expect = 1e-86
 Identities = 269/848 (31%), Positives = 375/848 (44%), Gaps = 160/848 (18%)

Query: 599  HQYSFAPDGEARLVSRCPADNPGLVQAQPRVPLTPTRGTSSRVAVQRGVGSGPHPPDTQQ 658
            H  S AP  E R     PA +P L    P+     T G  ++  +      GP     Q 
Sbjct: 14   HAVSLAPCDEPRRTLH-PAPSPSL---PPQCSYYTTEGWGAQALMAPVPCMGPPGRLQQA 69

Query: 659  P---SPSKAFKPRFPGDQVVNGAGPELSTGPSPGSPTLDIDQSIEQLNRLILELDPTFEP 715
            P   + +  F P  PG++ +           +P      ID S+E LN++ILELDPTF+ 
Sbjct: 70   PQVEAKATCFLPS-PGEKALG----------TPEDLDSYIDFSLESLNQMILELDPTFQL 118

Query: 716  IPTHMNALGSQANGSVSPDSVGGGLRASSRLPDTGEGPSRATGRQGSSAEQPLGGRLRKL 775
            +P                             P TG       G Q   A+  +  R ++ 
Sbjct: 119  LP-----------------------------PGTG-------GSQAELAQSTMSMRKKEE 142

Query: 776  SLGQYDNDAGGQLPFSKCAWGKAGVDYAPNLPPFPSPADVKETMTPGYPQDL-DIIDGRI 834
            S              S+C  G          PPF S       ++   P++     +  I
Sbjct: 143  SEALDIKYIEVTSARSRCHDGPQHCSSPSVTPPFGSLRSGGLLLSRDVPRETRSSSESLI 202

Query: 835  LSSKESMCSTPAFPVSPETPYVKTALRHPPFSPPE--PPLSSPASQHKGGREPRSCPETL 892
             S  +        P S      +     PP SP    P + S AS   G   P      L
Sbjct: 203  FSGNQGRGHQRPLPPS------EGLSPRPPNSPSISIPCMGSKASSPHGLGSPLVASPRL 256

Query: 893  THAVGMSESPIGPKSTMLRADASSTPSFQQAFASSCTISSNGPGQRRESSSSAERQWVES 952
               +G      G + ++L A   S  S+    + S   SSN   Q   SS S E      
Sbjct: 257  EKRLGGLAPQRGSRISVLSASPVSDVSYMFGSSQSLLHSSNSSHQ--SSSRSLES----- 309

Query: 953  SPKPMVSLLGSGRPTGSPLSAEFSGTRKDSPVLSCFPPSELQAPFHSHELSLAEPPDSLA 1012
                         P  S  S    G+     V  C  PS+ QAP  +  L++ +P    +
Sbjct: 310  -------------PANSSSSLHSLGS-----VSLCTRPSDFQAP-RNPTLTMGQPRTPHS 350

Query: 1013 PPSSQAFLGFGTAPVGSGLPPEEDLGALLANSHGASPTPSIPLTATGAADNGFLSHNFLT 1072
            PP                          LA  H +S  PSI                   
Sbjct: 351  PP--------------------------LAKEHASSCPPSIT------------------ 366

Query: 1073 VAPGHSSHHSPGLQGQGVTLPGQPPLPEKKRASEGDRSLGSVSPSSSGFSSPHSGSTIS- 1131
                +S    P +   G   PG  P P++    +     G+ SPS+   ++  +  T+S 
Sbjct: 367  ----NSMVDIPIVLINGCPEPGSSP-PQRTPGHQNSVQPGAASPSNPCPATRSNSQTLSD 421

Query: 1132 IPFPNVLPDFSKASEAASPLPDSPG-DKLVIVKFVQDTSKFWYKADISREQAIAMLKDKE 1190
             PF              +  P+ P  D    +KFV DTSK+W+K +I+REQAI +L+ +E
Sbjct: 422  APF--------------TTCPEGPARDMQPTMKFVMDTSKYWFKPNITREQAIELLRKEE 467

Query: 1191 PGSFIVRDSHSFRGAYGLAMKVATPPPSVLQLNKKAGDLANELVRHFLIECTPKGVRLKG 1250
            PG+F++RDS S+RG++GLA+KV   P S      + G+ +N+L+RHFLIE + KGV LKG
Sbjct: 468  PGAFVIRDSSSYRGSFGLALKVQEVPASA---QSRPGEDSNDLIRHFLIESSAKGVHLKG 524

Query: 1251 CSNEPYFGSLTALVCQHSITPLALPCKLLIPERDPLEEIAESSPQTAANSAAELLKQGAA 1310
               EPYFGSL+A VCQHSI  LALPCKL IP+R   E         + +S A   K+ A 
Sbjct: 525  ADEEPYFGSLSAFVCQHSIMALALPCKLTIPQR---ELGGADGASDSTDSPASCQKKSAG 581

Query: 1311 CNVWYLNSVEMESLTGHQAIQKALSITLVQEPPPVSTVVHFKVSAQGITLTDNQRKLFFR 1370
            C+  YL+SV +E+LTG  A+QKA+S T  ++  P  TVVHFKV+ QGITLTD QRK+FFR
Sbjct: 582  CHTLYLSSVSVETLTGALAVQKAISTTFERDILPTPTVVHFKVTEQGITLTDVQRKVFFR 641

Query: 1371 RHYPVNSVIFCALDPQDRKWIKDGPSSKVFGFVARKQGSATDNVCHLFAEHDPEQPASAI 1430
            RHYP+ ++ FC +DP+ RKW K    S +FGFVA+ Q    +NVCHLFAE+D  QPAS +
Sbjct: 642  RHYPLTTLRFCGMDPEQRKWQKYCKPSWIFGFVAKSQTEPQENVCHLFAEYDMVQPASQV 701

Query: 1431 VNFVSKVM 1438
            +  V+ ++
Sbjct: 702  IGLVTALL 709


>gi|73765544 phosphatase and tensin homolog [Homo sapiens]
          Length = 403

 Score =  145 bits (367), Expect = 2e-34
 Identities = 106/347 (30%), Positives = 158/347 (45%), Gaps = 45/347 (12%)

Query: 2   EEGHGLDLTYITERIIAVSFPAGCSEESYLHNLQEVTRMLKSKHGDNYLVLNL-SEKRYD 60
           E+G  LDLTYI   IIA+ FPA   E  Y +N+ +V R L SKH ++Y + NL +E+ YD
Sbjct: 18  EDGFDLDLTYIYPNIIAMGFPAERLEGVYRNNIDDVVRFLDSKHKNHYKIYNLCAERHYD 77

Query: 61  LTKLNPKIMDVGWPELHAPPLDKMCTICKAQESWLNSNLQHVVVIHCRGGKGRIGVVISS 120
             K N ++    + + + P L+ +   C+  + WL+ +  HV  IHC+ GKGR GV+I +
Sbjct: 78  TAKFNCRVAQYPFEDHNPPQLELIKPFCEDLDQWLSEDDNHVAAIHCKAGKGRTGVMICA 137

Query: 121 YMHFTNVSASADQALDRFAMKKFYDDKVSALMQPSQKRYVQFLSGLLSGSVKMNASPLFL 180
           Y+        A +ALD +   +  D K   +  PSQ+RYV + S LL   +      L  
Sbjct: 138 YLLHRGKFLKAQEALDFYGEVRTRDKK--GVTIPSQRRYVYYYSYLLKNHLDYRPVALLF 195

Query: 181 HFVILHGTPNFDTGGVCRPFLKLYQAMQPVYTSGIYNVGPENPSRICIVIEPAQLLK--G 238
           H ++    P F +GG C P   + Q    +Y+S   N GP       +  E  Q L   G
Sbjct: 196 HKMMFETIPMF-SGGTCNPQFVVCQLKVKIYSS---NSGPTRREDKFMYFEFPQPLPVCG 251

Query: 239 DVMVKCYHKKYRSATRDVIFRLQFHTGAVQG----------------------------- 269
           D+ V+ +HK+ +   +D +F    +T  + G                             
Sbjct: 252 DIKVEFFHKQNKMLKKDKMFHFWVNTFFIPGPEETSEKVENGSLCDQEIDSICSIERADN 311

Query: 270 ----YGLVFGKEDLDNASKDDR---FPDYGKVELVFSATPEKIQGSE 309
                 L   K DLD A+KD     F    KV+L F+ T E+    E
Sbjct: 312 DKEYLVLTLTKNDLDKANKDKANRYFSPNFKVKLYFTKTVEEPSNPE 358


>gi|157384971 cyclin G associated kinase [Homo sapiens]
          Length = 1311

 Score =  136 bits (342), Expect = 2e-31
 Identities = 88/309 (28%), Positives = 157/309 (50%), Gaps = 18/309 (5%)

Query: 7   LDLTYITERIIAVSFPAGCSEESYLHNLQEVTRMLKSKHGDNYLVLNLSEKRYDLTKLNP 66
           LD++YIT RI  +SFPA   E +  +N+++V   L SKH  +Y V NLS + Y  ++ + 
Sbjct: 408 LDISYITSRIAVMSFPAEGVESALKNNIEDVRLFLDSKHPGHYAVYNLSPRTYRPSRFHN 467

Query: 67  KIMDVGWPELHAPPLDKMCTICKAQESWLNSNLQHVVVIHCRGGKGRIGVVISSYMHFTN 126
           ++ + GW    AP L  +  IC+   +WL  + ++V V+HC  G+    V + S++ F  
Sbjct: 468 RVSECGWAARRAPHLHTLYNICRNMHAWLRQDHKNVCVVHCMDGRAASAVAVCSFLCFCR 527

Query: 127 VSASADQALDRFAMKKFYDDKVSALMQPSQKRYVQFLSGLLSGS-VKMNASPLFLHFVIL 185
           + ++A+ A+  F+MK     +    + PS KRY++++  +++   +  ++ P+ +  V++
Sbjct: 528 LFSTAEAAVYMFSMK-----RCPPGIWPSHKRYIEYMCDMVAEEPITPHSKPILVRAVVM 582

Query: 186 HGTPNFD-TGGVCRPFLKLYQAMQPV-YTSGIYNVGPENPSRICIVIEPAQL-LKGDVMV 242
              P F      CRPF ++Y   + V  TS  Y+   +        + P  + ++GDV++
Sbjct: 583 TPVPLFSKQRSGCRPFCEVYVGDERVASTSQEYDKMRDFKIEDGKAVIPLGVTVQGDVLI 642

Query: 243 KCYHKKYRSATR-------DVIFRLQFHTGAV--QGYGLVFGKEDLDNASKDDRFPDYGK 293
             YH +     R         +F++QFHTG V      + F K DLD     +++PD  +
Sbjct: 643 VIYHARSTLGGRLQAKMASMKMFQIQFHTGFVPRNATTVKFAKYDLDACDIQEKYPDLFQ 702

Query: 294 VELVFSATP 302
           V L     P
Sbjct: 703 VNLEVEVEP 711


>gi|40549435 transmembrane phosphatase with tensin homology isoform
           gamma [Homo sapiens]
          Length = 513

 Score =  122 bits (305), Expect = 3e-27
 Identities = 88/323 (27%), Positives = 154/323 (47%), Gaps = 26/323 (8%)

Query: 3   EGHGLDLTYITERIIAVSFPAGCSEESYLHNLQEVTRMLKSKHGDNYLVLNL-SEKRYDL 61
           +G  LDLTY+TERIIA+SFP+   +  Y + ++EV R L  KH ++Y V NL SE+ YD 
Sbjct: 195 DGFDLDLTYVTERIIAMSFPSSGRQSFYRNPIKEVVRFLDKKHRNHYRVYNLCSERAYDP 254

Query: 62  TKLNPKIMDVGWPELHAPPLDKMCTICKAQESWLNSNLQHVVVIHCRGGKGRIGVVISSY 121
              + +++ +   + + P L +M    K    W+  +L+++V IHC+GG  R G ++ ++
Sbjct: 255 KHFHNRVVRIMIDDHNVPTLHQMVVFTKEVNEWMAQDLENIVAIHCKGGTDRTGTMVCAF 314

Query: 122 MHFTNVSASADQALDRFAMK---KFYDDKVSALMQPSQKRYVQFLSGLLSGSVKMNASP- 177
           +  + + ++A ++L  F  +   K + +K   +  PSQKRYV + +  +      N  P 
Sbjct: 315 LIASEICSTAKESLYYFGERRTDKTHSEKFQGVETPSQKRYVAYFA-QVKHLYNWNLPPR 373

Query: 178 --LFLHFVILHGTPNFDTGGVCRPFLKLYQAMQPVYTSGIYNVGP------ENPSRICIV 229
             LF+   I++  P +         LK+   M+        ++G           +I I 
Sbjct: 374 RILFIKHFIIYSIPRYVRD------LKIQIEMEKKVVFSTISLGKCSVLDNITTDKILID 427

Query: 230 IEPAQLLKGDVMVKCYHKKYRSATRDVIFRLQFHTGAVQGYGLVFGKEDLDNASKDDR-- 287
           +     L  DV V+ ++    +   +  F    HT  ++   L   K +LDN  K     
Sbjct: 428 VFDGLPLYDDVKVQFFYSNLPTYYDNCSFYFWLHTSFIENNRLYLPKNELDNLHKQKARR 487

Query: 288 -FPDYGKVELVFSATPEKIQGSE 309
            +P    VE++F    EK+  S+
Sbjct: 488 IYPSDFAVEILFG---EKMTSSD 507


>gi|40549433 transmembrane phosphatase with tensin homology isoform
           beta [Homo sapiens]
          Length = 533

 Score =  122 bits (305), Expect = 3e-27
 Identities = 88/323 (27%), Positives = 154/323 (47%), Gaps = 26/323 (8%)

Query: 3   EGHGLDLTYITERIIAVSFPAGCSEESYLHNLQEVTRMLKSKHGDNYLVLNL-SEKRYDL 61
           +G  LDLTY+TERIIA+SFP+   +  Y + ++EV R L  KH ++Y V NL SE+ YD 
Sbjct: 215 DGFDLDLTYVTERIIAMSFPSSGRQSFYRNPIKEVVRFLDKKHRNHYRVYNLCSERAYDP 274

Query: 62  TKLNPKIMDVGWPELHAPPLDKMCTICKAQESWLNSNLQHVVVIHCRGGKGRIGVVISSY 121
              + +++ +   + + P L +M    K    W+  +L+++V IHC+GG  R G ++ ++
Sbjct: 275 KHFHNRVVRIMIDDHNVPTLHQMVVFTKEVNEWMAQDLENIVAIHCKGGTDRTGTMVCAF 334

Query: 122 MHFTNVSASADQALDRFAMK---KFYDDKVSALMQPSQKRYVQFLSGLLSGSVKMNASP- 177
           +  + + ++A ++L  F  +   K + +K   +  PSQKRYV + +  +      N  P 
Sbjct: 335 LIASEICSTAKESLYYFGERRTDKTHSEKFQGVETPSQKRYVAYFA-QVKHLYNWNLPPR 393

Query: 178 --LFLHFVILHGTPNFDTGGVCRPFLKLYQAMQPVYTSGIYNVGP------ENPSRICIV 229
             LF+   I++  P +         LK+   M+        ++G           +I I 
Sbjct: 394 RILFIKHFIIYSIPRYVRD------LKIQIEMEKKVVFSTISLGKCSVLDNITTDKILID 447

Query: 230 IEPAQLLKGDVMVKCYHKKYRSATRDVIFRLQFHTGAVQGYGLVFGKEDLDNASKDDR-- 287
           +     L  DV V+ ++    +   +  F    HT  ++   L   K +LDN  K     
Sbjct: 448 VFDGLPLYDDVKVQFFYSNLPTYYDNCSFYFWLHTSFIENNRLYLPKNELDNLHKQKARR 507

Query: 288 -FPDYGKVELVFSATPEKIQGSE 309
            +P    VE++F    EK+  S+
Sbjct: 508 IYPSDFAVEILFG---EKMTSSD 527


>gi|109689707 transmembrane phosphatase with tensin homology isoform
           alpha [Homo sapiens]
          Length = 551

 Score =  122 bits (305), Expect = 3e-27
 Identities = 88/323 (27%), Positives = 154/323 (47%), Gaps = 26/323 (8%)

Query: 3   EGHGLDLTYITERIIAVSFPAGCSEESYLHNLQEVTRMLKSKHGDNYLVLNL-SEKRYDL 61
           +G  LDLTY+TERIIA+SFP+   +  Y + ++EV R L  KH ++Y V NL SE+ YD 
Sbjct: 233 DGFDLDLTYVTERIIAMSFPSSGRQSFYRNPIKEVVRFLDKKHRNHYRVYNLCSERAYDP 292

Query: 62  TKLNPKIMDVGWPELHAPPLDKMCTICKAQESWLNSNLQHVVVIHCRGGKGRIGVVISSY 121
              + +++ +   + + P L +M    K    W+  +L+++V IHC+GG  R G ++ ++
Sbjct: 293 KHFHNRVVRIMIDDHNVPTLHQMVVFTKEVNEWMAQDLENIVAIHCKGGTDRTGTMVCAF 352

Query: 122 MHFTNVSASADQALDRFAMK---KFYDDKVSALMQPSQKRYVQFLSGLLSGSVKMNASP- 177
           +  + + ++A ++L  F  +   K + +K   +  PSQKRYV + +  +      N  P 
Sbjct: 353 LIASEICSTAKESLYYFGERRTDKTHSEKFQGVETPSQKRYVAYFA-QVKHLYNWNLPPR 411

Query: 178 --LFLHFVILHGTPNFDTGGVCRPFLKLYQAMQPVYTSGIYNVGP------ENPSRICIV 229
             LF+   I++  P +         LK+   M+        ++G           +I I 
Sbjct: 412 RILFIKHFIIYSIPRYVRD------LKIQIEMEKKVVFSTISLGKCSVLDNITTDKILID 465

Query: 230 IEPAQLLKGDVMVKCYHKKYRSATRDVIFRLQFHTGAVQGYGLVFGKEDLDNASKDDR-- 287
           +     L  DV V+ ++    +   +  F    HT  ++   L   K +LDN  K     
Sbjct: 466 VFDGLPLYDDVKVQFFYSNLPTYYDNCSFYFWLHTSFIENNRLYLPKNELDNLHKQKARR 525

Query: 288 -FPDYGKVELVFSATPEKIQGSE 309
            +P    VE++F    EK+  S+
Sbjct: 526 IYPSDFAVEILFG---EKMTSSD 545


>gi|7662146 DnaJ (Hsp40) homolog, subfamily C, member 6 [Homo
           sapiens]
          Length = 913

 Score =  121 bits (304), Expect = 4e-27
 Identities = 95/366 (25%), Positives = 163/366 (44%), Gaps = 40/366 (10%)

Query: 7   LDLTYITERIIAVSFPAGCSEESYLHNLQEVTRMLKSKHGDNYLVLNLSEKRYDLTKLNP 66
           LD TY+T RII +SFP    +  + + + ++   L S+H D+Y V NLS K Y   K + 
Sbjct: 64  LDFTYVTSRIIVMSFPLDNVDIGFRNQVDDIRSFLDSRHLDHYTVYNLSPKSYRTAKFHS 123

Query: 67  KIMDVGWPELHAPPLDKMCTICKAQESWLNSNLQHVVVIHCRGGKGRIGVVISSYMHFTN 126
           ++ +  WP   AP L  +  +C+   +WL  N ++V V+HC  G+    +++ +   F N
Sbjct: 124 RVSECSWPIRQAPSLHNLFAVCRNMYNWLLQNPKNVCVVHCLDGRAASSILVGAMFIFCN 183

Query: 127 VSASADQALDRFAMKKFYDDKVSALMQPSQKRYVQFLSGLLSGS-VKMNASPLFLHFVIL 185
           + ++   A+     +  Y  +    + PS +RY+ ++  LL+    + +  PL +  + +
Sbjct: 184 LYSTPGPAI-----RLLYAKRPGIGLSPSHRRYLGYMCDLLADKPYRPHFKPLTIKSITV 238

Query: 186 HGTPNFD-TGGVCRPFLKLYQAMQPVY-TSGIYNVGPENPSRICIVIEPAQL-LKGDVMV 242
              P F+     CRP+  +      +Y T   +    E   +   +  P  + ++GDV+V
Sbjct: 239 SPIPFFNKQRNGCRPYCDVLIGETKIYSTCTDFERMKEYRVQDGKIFIPLNITVQGDVVV 298

Query: 243 KCYH-------KKYRSATRDVIFRLQFHTGAV--QGYGLVFGKEDLDNASKDDRFPDYGK 293
             YH       +     T   IF+LQFHTG +      L F K +LD     +++P   +
Sbjct: 299 SMYHLRSTIGSRLQAKVTNTQIFQLQFHTGFIPLDTTVLKFTKPELDACDVPEKYPQLFQ 358

Query: 294 VELVFSATPEKIQGSEHLYNDHGVIVD-------YNTTD--PLIRWDSYENLSADGEVLH 344
           V L     P            H  ++D       Y T D  P I + S++    D   L 
Sbjct: 359 VTLDVELQP------------HDKVIDLTPPWEHYCTKDVNPSILFSSHQE-HQDTLALG 405

Query: 345 TQGPVD 350
            Q P+D
Sbjct: 406 GQAPID 411


>gi|213972593 TPTE and PTEN homologous inositol lipid phosphatase
           isoform delta [Homo sapiens]
          Length = 411

 Score =  119 bits (297), Expect = 3e-26
 Identities = 86/310 (27%), Positives = 149/310 (48%), Gaps = 19/310 (6%)

Query: 3   EGHGLDLTYITERIIAVSFPAGCSEESYLHNLQEVTRMLKSKHGDNYLVLNL-SEKRYDL 61
           +G  LDLTY+TERIIA+SFP+   +  Y + ++EV R L  KH ++Y V NL SE+ YD 
Sbjct: 104 DGFDLDLTYVTERIIAMSFPSSGRQSFYRNPIEEVVRFLDKKHRNHYRVYNLCSERAYDP 163

Query: 62  TKLNPKIMDVGWPELHAPPLDKMCTICKAQESWLNSNLQHVVVIHCRGGKGRIGVVISSY 121
              + ++  +   + + P L +M    K    W+  +L+++V IHC+GGKGR G ++ + 
Sbjct: 164 KHFHNRVSRIMIDDHNVPTLHEMVVFTKEVNEWMAQDLENIVAIHCKGGKGRTGTMVCAL 223

Query: 122 MHFTNVSASADQALDRFAMK---KFYDDKVSALMQPSQKRYVQFLSGLLSGSVKMNASP- 177
           +  + +  +A+++L  F  +   K + +K   +  PSQ RYV + +  +      N  P 
Sbjct: 224 LIASEIFLTAEESLYYFGERRTNKTHSNKFQGVETPSQNRYVGYFA-QVKHLYNWNLPPR 282

Query: 178 --LFLHFVILHGTPNFDTGGVCRPFLKLYQAMQPVYTSGIYN----VGPENPSRICIVIE 231
             LF+   I++       G VC   +++    + V++S        +      +I I + 
Sbjct: 283 RILFIKRFIIYSI----RGDVCDLKVQVVMEKKVVFSSTSLGNCSILHDIETDKILINVY 338

Query: 232 PAQLLKGDVMVKCYHKKYRSATRDVIFRLQFHTGAVQGYGLVFGKEDLDNASKDDR---F 288
               L  DV V+ +         +  F   F+T  +Q   L   + +LDN  K      +
Sbjct: 339 DGPPLYDDVKVQFFSSNLPKYYDNCPFFFWFNTSFIQNNRLCLPRNELDNPHKQKAWKIY 398

Query: 289 PDYGKVELVF 298
           P    VE++F
Sbjct: 399 PPEFAVEILF 408


>gi|213972591 TPTE and PTEN homologous inositol lipid phosphatase
           isoform gamma [Homo sapiens]
          Length = 522

 Score =  119 bits (297), Expect = 3e-26
 Identities = 86/310 (27%), Positives = 149/310 (48%), Gaps = 19/310 (6%)

Query: 3   EGHGLDLTYITERIIAVSFPAGCSEESYLHNLQEVTRMLKSKHGDNYLVLNL-SEKRYDL 61
           +G  LDLTY+TERIIA+SFP+   +  Y + ++EV R L  KH ++Y V NL SE+ YD 
Sbjct: 215 DGFDLDLTYVTERIIAMSFPSSGRQSFYRNPIEEVVRFLDKKHRNHYRVYNLCSERAYDP 274

Query: 62  TKLNPKIMDVGWPELHAPPLDKMCTICKAQESWLNSNLQHVVVIHCRGGKGRIGVVISSY 121
              + ++  +   + + P L +M    K    W+  +L+++V IHC+GGKGR G ++ + 
Sbjct: 275 KHFHNRVSRIMIDDHNVPTLHEMVVFTKEVNEWMAQDLENIVAIHCKGGKGRTGTMVCAL 334

Query: 122 MHFTNVSASADQALDRFAMK---KFYDDKVSALMQPSQKRYVQFLSGLLSGSVKMNASP- 177
           +  + +  +A+++L  F  +   K + +K   +  PSQ RYV + +  +      N  P 
Sbjct: 335 LIASEIFLTAEESLYYFGERRTNKTHSNKFQGVETPSQNRYVGYFA-QVKHLYNWNLPPR 393

Query: 178 --LFLHFVILHGTPNFDTGGVCRPFLKLYQAMQPVYTSGIYN----VGPENPSRICIVIE 231
             LF+   I++       G VC   +++    + V++S        +      +I I + 
Sbjct: 394 RILFIKRFIIYSI----RGDVCDLKVQVVMEKKVVFSSTSLGNCSILHDIETDKILINVY 449

Query: 232 PAQLLKGDVMVKCYHKKYRSATRDVIFRLQFHTGAVQGYGLVFGKEDLDNASKDDR---F 288
               L  DV V+ +         +  F   F+T  +Q   L   + +LDN  K      +
Sbjct: 450 DGPPLYDDVKVQFFSSNLPKYYDNCPFFFWFNTSFIQNNRLCLPRNELDNPHKQKAWKIY 509

Query: 289 PDYGKVELVF 298
           P    VE++F
Sbjct: 510 PPEFAVEILF 519


>gi|213972589 TPTE and PTEN homologous inositol lipid phosphatase
           isoform alpha [Homo sapiens]
          Length = 445

 Score =  119 bits (297), Expect = 3e-26
 Identities = 86/310 (27%), Positives = 149/310 (48%), Gaps = 19/310 (6%)

Query: 3   EGHGLDLTYITERIIAVSFPAGCSEESYLHNLQEVTRMLKSKHGDNYLVLNL-SEKRYDL 61
           +G  LDLTY+TERIIA+SFP+   +  Y + ++EV R L  KH ++Y V NL SE+ YD 
Sbjct: 138 DGFDLDLTYVTERIIAMSFPSSGRQSFYRNPIEEVVRFLDKKHRNHYRVYNLCSERAYDP 197

Query: 62  TKLNPKIMDVGWPELHAPPLDKMCTICKAQESWLNSNLQHVVVIHCRGGKGRIGVVISSY 121
              + ++  +   + + P L +M    K    W+  +L+++V IHC+GGKGR G ++ + 
Sbjct: 198 KHFHNRVSRIMIDDHNVPTLHEMVVFTKEVNEWMAQDLENIVAIHCKGGKGRTGTMVCAL 257

Query: 122 MHFTNVSASADQALDRFAMK---KFYDDKVSALMQPSQKRYVQFLSGLLSGSVKMNASP- 177
           +  + +  +A+++L  F  +   K + +K   +  PSQ RYV + +  +      N  P 
Sbjct: 258 LIASEIFLTAEESLYYFGERRTNKTHSNKFQGVETPSQNRYVGYFA-QVKHLYNWNLPPR 316

Query: 178 --LFLHFVILHGTPNFDTGGVCRPFLKLYQAMQPVYTSGIYN----VGPENPSRICIVIE 231
             LF+   I++       G VC   +++    + V++S        +      +I I + 
Sbjct: 317 RILFIKRFIIYSI----RGDVCDLKVQVVMEKKVVFSSTSLGNCSILHDIETDKILINVY 372

Query: 232 PAQLLKGDVMVKCYHKKYRSATRDVIFRLQFHTGAVQGYGLVFGKEDLDNASKDDR---F 288
               L  DV V+ +         +  F   F+T  +Q   L   + +LDN  K      +
Sbjct: 373 DGPPLYDDVKVQFFSSNLPKYYDNCPFFFWFNTSFIQNNRLCLPRNELDNPHKQKAWKIY 432

Query: 289 PDYGKVELVF 298
           P    VE++F
Sbjct: 433 PPEFAVEILF 442


>gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapiens]
          Length = 1124

 Score = 60.1 bits (144), Expect = 2e-08
 Identities = 144/591 (24%), Positives = 192/591 (32%), Gaps = 68/591 (11%)

Query: 605  PDGEARLVSRCPADNPGLVQAQPRVPLTPTRGTSSRVAVQRGVGSGPHPPD--------- 655
            P   A   SR PA  P       R P  P + TS       G  SG   P          
Sbjct: 79   PTRSAGTSSRNPASRPPASGRGERAP--PAKNTSPGPVSSPGRASGTTRPGPLGQKGLRI 136

Query: 656  TQQPSPSKAFKPRFPGDQVVNGAGPELSTGPSPGSPTLDIDQSIEQLNRLILELDPTFEP 715
            + + + ++      P    ++      ++GP+PG+P+  + +        +    P    
Sbjct: 137  SAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSA 196

Query: 716  IPTHMNALGSQANGSVSPDSVGGGLRASSRLPDTGEGPSRATGRQGSSAEQPLGGRLRK- 774
             P        ++  S S  S      A+ R P  G G  R   R  SS+  PL    R  
Sbjct: 197  RPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSG 256

Query: 775  -LSLGQYDNDAGGQLPFSKCAWG-------KAGVDYAPNLPPF-------PSPADVKETM 819
              + G     A    P  K               D AP L P        PSP+  K   
Sbjct: 257  PSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSGTKARP 316

Query: 820  TPGYPQDLDIIDGRILSSKESMCSTPAFPVSPETPYVKTALRHPPFSPPE--------PP 871
             P        +   +  S       P  P SP  P     L  PP +PP         PP
Sbjct: 317  VPPPDNAATPLPATLPPSPPLATPLPLAPPSPSAPPSLQTLPSPPATPPSQAPPSMTTPP 376

Query: 872  LSSPASQHKGGREPRSCPETLTH-AVGMSESPIGPKSTMLRADASSTPSFQQAFASSCTI 930
            + +P S       P   P +LT  ++    SP+   S  L+A  S      QA  S  T+
Sbjct: 377  MQAPPSLQT--IPPIQVPHSLTSPSLQAPPSPLALSS--LQATTSLGSPTLQATHSFLTM 432

Query: 931  SSNGPGQRRESSSSAERQWVESSPKPMVS----------LLGSGRPTGSPLSAEFSGTRK 980
            S   P Q + S +S  R        P +           L  S  P  SPLS+    T  
Sbjct: 433  S---PRQTQASLTSPSRPASTPPDSPPLQAPLSLPASPPLQTSLSPAVSPLSSPL--TIH 487

Query: 981  DSPVLSCFPPSELQAPFHSHELSLAEPPDSLAPPSSQAFLGFGTAPVGSGLPPEEDLGAL 1040
                LS       QAP  S  +   E   SLAPPS Q      T P     PP E+L +L
Sbjct: 488  PLQALSSLASHSPQAPLSSLIMPPLETQSSLAPPSLQ------TPPASLTTPPLENLPSL 541

Query: 1041 LANSHGASPTPSIPLTATGAADNGFLSHNFLTVAPGHSSHHSPGLQGQGVTLPGQPPLPE 1100
               +     T S PLT          +   L   P   +   P       T P Q P   
Sbjct: 542  ---APPPLQTASAPLTTPHLETPPCPAPCPLQAPPSPLTTPPPETPSSIATPPPQAP--- 595

Query: 1101 KKRASEGDRSLGSVSPSSSGFSSPHSGSTISIPFPNVLPDFSKASEAASPL 1151
               AS   + L S   S      P +   +++P P   P    AS   SPL
Sbjct: 596  PALASPPLQGLPSPPLSPLATPPPQAPPXLALP-PLQAPPSPPASPPLSPL 645



 Score = 45.8 bits (107), Expect = 3e-04
 Identities = 91/347 (26%), Positives = 119/347 (34%), Gaps = 51/347 (14%)

Query: 839  ESMCSTPAFPVSPETPYVKTALRHPPFSPPEPPLSSPASQHKGGREPRSCPETLTHAVGM 898
            + + S P  P++   P     L  PP   P  P +SP         P++ P  L  AV +
Sbjct: 604  QGLPSPPLSPLATPPPQAPPXLALPPLQAPPSPPASPPLSPLATPSPQA-PNAL--AVHL 660

Query: 899  SESPIGPKSTMLRADASSTPSFQQAFASSCTISSNGPGQRRESSSSAERQWVESSP--KP 956
             ++P  P  +     A  +P      + S T  S  P      S +A    V  SP   P
Sbjct: 661  LQAPFSPPPSP-PVQAPFSPPASPPVSPSATPPSQAP-----PSLAAPPLQVPPSPPASP 714

Query: 957  MVSLLGSGRPTGSPLSAEFSGTRKDSPVLSCFPPSELQAPFHSHELSLAEPPDSLAPPSS 1016
             +S   +  P   P  A        SP  S  PP    A        L   P    PPS 
Sbjct: 715  PMSPSATPPPQAPPPLAAPPLQVPPSPPAS--PPMSPSATPPPRVPPLLAAPPLQVPPSP 772

Query: 1017 QAFLGFG-------TAPVGSGLPPEEDLGALLANSHGASP------TPSIPLTATGAADN 1063
             A L           AP     PP + L +  A+  G +P       P  PL        
Sbjct: 773  PASLPMSPLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAP 832

Query: 1064 GFLSHNFLTVAPGHSSHHSPGLQGQGVTLPGQPPLPEKKRASEGDRSLGSVSPS------ 1117
              L+   L V P  S   SP LQ      P +PP P    +  G R   +++P       
Sbjct: 833  PVLAAPLLQVPP--SPPASPTLQA-----PRRPPTPGPDTSVSGPRLTLALAPGPPPPPS 885

Query: 1118 ---SSGFSSP----HSGSTISIPFPNVLPDFSKASE---AASPLPDS 1154
               SS  S P    HS S  S   P  L  +    E   AASP PD+
Sbjct: 886  RSPSSTLSGPDLAGHSSSATST--PEELRGYDSGPEGGAAASPPPDA 930



 Score = 32.0 bits (71), Expect = 4.4
 Identities = 68/287 (23%), Positives = 98/287 (34%), Gaps = 48/287 (16%)

Query: 803  APNLPPFPSPADVKETMTPGYPQDLDIIDGRILSSKESMCSTPAF----------PVSPE 852
            AP  PP   P     T +P  P  L +    +L +  S   +P            PVSP 
Sbjct: 632  APPSPPASPPLSPLATPSPQAPNALAV---HLLQAPFSPPPSPPVQAPFSPPASPPVSPS 688

Query: 853  TPYVKTA--------LRHPPFSPPEPPLSSPASQHKGGREPRSCPETLTHAVGMSESPIG 904
                  A        L+ PP  P  PP+S  A+       P + P         +  P+ 
Sbjct: 689  ATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQVPPSPPASPPMS 748

Query: 905  PKST-------MLRADASSTPSFQQAFASSCTISSNGPGQRRESSSSAERQWVESSPKPM 957
            P +T       +L A     P    A      ++   P    ++  +     +++ P P 
Sbjct: 749  PSATPPPRVPPLLAAPPLQVPPSPPASLPMSPLAKPPP----QAPPALATPPLQALPSPP 804

Query: 958  VSLLGSG--RPTGS-PLSAEFSGTRKDSPVLSC----FPPS-----ELQAPFHSHELSLA 1005
             S  G     P+ S P+S   +   +  PVL+      PPS      LQAP         
Sbjct: 805  ASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAP---RRPPTP 861

Query: 1006 EPPDSLAPPSSQAFLGFGTAPVGSGLPPEEDLGALLA-NSHGASPTP 1051
             P  S++ P     L  G  P  S  P     G  LA +S  A+ TP
Sbjct: 862  GPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTP 908


>gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapiens]
          Length = 855

 Score = 58.9 bits (141), Expect = 3e-08
 Identities = 134/550 (24%), Positives = 183/550 (33%), Gaps = 83/550 (15%)

Query: 633  PTRGTSSRVAVQRGVGSGPHPPDTQQPSPSKAFKPRFPGD---QVVNGAGPELSTGPSPG 689
            PT GT S    +R   +G    +   P P+ + +PR P +   + V+ A    +T PSP 
Sbjct: 167  PTPGTPSPAMARRSRAAGT---EVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPA 223

Query: 690  S---PTLDIDQSIEQLNRLILELDPTFEPIPTHMNALGSQANGSVSPDSVGGGLRASSRL 746
            +   P+            L     P   P  +  +A G+    +        GL+A  R 
Sbjct: 224  ARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQAL-RP 282

Query: 747  PDTGEGPSRATGRQGSSAEQPLGGRLRKLSLGQYDNDAGGQLPFSKCAWGKAGVDYAPNL 806
            P        A    G  +  PL       +L           P S     +      P  
Sbjct: 283  PQVTPPRKDAAPALGPLSSSPLATPSPSAALQSQAPPTLPATPHSSSLTCQLATPL-PLA 341

Query: 807  PPFPSPADVKETM-----TPGYPQDLDIIDGRILSSKESMCSTPAFPVSPETPYVKTALR 861
            PP PS     +T+     TP       +    + ++   + S P  P++   P    AL 
Sbjct: 342  PPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALA 401

Query: 862  HPPF-SPPEPPLSSPASQHKGGREPRSCPETLTHAVGMSESPIGPKSTMLRADASSTPSF 920
             PP  +PP PP S P S           P  L  AV + ++P  P  +     A  +P  
Sbjct: 402  LPPLQAPPSPPASPPLSPL--ATPSPQAPNAL--AVHLLQAPFSPPPSP-PVQAPFSPPA 456

Query: 921  QQAFASSCTISSNGPGQRRESSSSAERQWVESSPKPMVSLLGSGRPTGSPLSAEFSGTRK 980
                + S T  S  P      S +A    V  SP           P   P+S        
Sbjct: 457  SPPVSPSATPPSQAP-----PSLAAPPLQVPPSP-----------PASPPMSP------- 493

Query: 981  DSPVLSCFPPSELQAPFHSHELSLAEPPDSLAPPSSQAFLGFGTAPVGSGLPPEEDLGAL 1040
                 S  PP +   P       LA PP  LA P  QA     T P+ +   P       
Sbjct: 494  -----SATPPPQAPPP-------LAAPPLQLAKPPPQAPPALATPPLQALPSPPASFPGQ 541

Query: 1041 LANSHGASPTPSIPLTATGAADNGFLSHNFLTVAPGHSSHHSPGLQGQGVTLPGQPPLPE 1100
               S  AS  P  PL          L+   L V P  S   SP LQ      P +PP P 
Sbjct: 542  APFSPSAS-LPMSPLATPPPQAPPVLAAPLLQVPP--SPPASPTLQA-----PRRPPTPG 593

Query: 1101 KKRASEGDRSLGSVSPS---------SSGFSSP----HSGSTISIPFPNVLPDFSKASE- 1146
               +  G R   +++P          SS  S P    HS S  S   P  L  +    E 
Sbjct: 594  PDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATST--PEELRGYDSGPEG 651

Query: 1147 --AASPLPDS 1154
              AASP PD+
Sbjct: 652  GAAASPPPDA 661


>gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapiens]
          Length = 816

 Score = 55.1 bits (131), Expect = 5e-07
 Identities = 138/594 (23%), Positives = 190/594 (31%), Gaps = 88/594 (14%)

Query: 604  APDGEARLVSRCPADNPGLVQAQPRVPLTPTRGTSSRVAVQRGVGSGPHPPD-------- 655
            AP       SR PA   G      R P  P + TS       G  SG   P         
Sbjct: 74   APRAGPTRTSRPPASGRG-----ERAP--PAKNTSPGPVSSPGRASGTTRPGPLGQKGLR 126

Query: 656  -TQQPSPSKAFKPRFPGDQVVNGAGPELSTGPSPGSPTLDIDQSIEQLNRLILELDPTFE 714
             + + + ++      P    ++      ++GP+PG+P+  + +        +    P   
Sbjct: 127  ISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPS 186

Query: 715  PIPTHMNALGSQANGSVSPDSVGGGLRASSRLPDTGEGPSRATGRQGSSAEQPLGGRLRK 774
              P        ++  S S  S      A+ R P  G G  R   R  SS+  PL    R 
Sbjct: 187  ARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARS 246

Query: 775  LSLGQYDNDAGGQLPFSKCAWGKAGVDYAPNLPPFPSPADVKETMTPGY-PQDLDIIDGR 833
                +                   G   AP  P  P P  ++    P   P   D     
Sbjct: 247  GPSAR-------------------GTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPAL 287

Query: 834  -ILSSKESMCSTPAFPVSPETPYVKTALRHPPFSPPE---PPLSSPASQHKGGREPRSCP 889
              LSS      +P+ P SP  P     L  PP +PP      L SP  Q      P   P
Sbjct: 288  GPLSSSPLATPSPSAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLP--SP 345

Query: 890  ETLTHAVGMSESPIGPKSTMLRADASSTPSFQQAFASSCTISSNGPGQRRESSSSAERQW 949
                 A    ++P  P   +    A  +P      +   T S   P     ++ +     
Sbjct: 346  PLSPLATPPPQAP--PALALPPLQAPPSPPASPPLSPLATPSPQAP-----NALAVHLLQ 398

Query: 950  VESSPKPMVSLLGSGRPTGSPLSAEFSGTRKDSPVLSCFPPSEL-QAPFHSHELS----- 1003
               SP P   +     P  SP  +  +     +P     PP ++  +P  S  +S     
Sbjct: 399  APFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATP 458

Query: 1004 -------LAEPPDSLAPPSSQAFLGFGTAPVGSGLPPEEDLGALLANSHGASPTPSIPLT 1056
                   LA PP  LA P  QA     T P+ +   P          S  AS  P  PL 
Sbjct: 459  PPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSAS-LPMSPLA 517

Query: 1057 ATGAADNGFLSHNFLTVAPGHSSHHSPGLQGQGVTLPGQPPLPEKKRASEGDRSLGSVSP 1116
                     L+   L V P  S   SP LQ      P +PP P    +  G R   +++P
Sbjct: 518  TPPPQAPPVLAAPLLQVPP--SPPASPTLQA-----PRRPPTPGPDTSVSGPRLTLALAP 570

Query: 1117 S---------SSGFSSP----HSGSTISIPFPNVLPDFSKASE---AASPLPDS 1154
                      SS  S P    HS S  S   P  L  +    E   AASP PD+
Sbjct: 571  GPPPPPSRSPSSTLSGPDLAGHSSSATST--PEELRGYDSGPEGGAAASPPPDA 622


>gi|83367077 mucin 16 [Homo sapiens]
          Length = 14507

 Score = 52.8 bits (125), Expect = 2e-06
 Identities = 82/378 (21%), Positives = 136/378 (35%), Gaps = 45/378 (11%)

Query: 711   PTFEPIPTHMNALGSQANGSVSPDSVGGGLRASSRLPDTGEGPSRATGRQGSSAEQPL-- 768
             PT    PT    + S    S S  S    L  +S  P+T +      G + SS    L  
Sbjct: 11196 PTLAVSPTVQGLVTSLVTSSGSETSAFSNLTVASSQPETIDSWVAHPGTEASSVVPTLTV 11255

Query: 769   --GGRLRKLSLGQYDNDAGGQLPFSKCAWGKAGVDYAPNL---PPFPSPADVKETMTPGY 823
               G     +SL  +  ++   LP +   +  + +D  P+    P   S + +  T++PG 
Sbjct: 11256 STGEPFTNISLVTHPAESSSTLPRTTSRFSHSELDTMPSTVTSPEAESSSAISTTISPGI 11315

Query: 824   PQDLDIIDGRILSSKESMCSTPAFPVSPETPYVKTA----LRHPPFSPPEPPLSSPASQH 879
             P    ++   + SS   + +T  FP  PE+P+   A    + HP  +    P ++P   H
Sbjct: 11316 P---GVLTSLVTSSGRDISAT--FPTVPESPHESEATASWVTHPAVTSTTVPRTTPNYSH 11370

Query: 880   KGGREPRSCPETLTH--AVGMSESP---IGPK-STMLRADASSTPSFQQAFASSCTISSN 933
                 EP + P   T   A   S+ P   + P    M+ +  +S+ +       + T+SS 
Sbjct: 11371 S---EPDTTPSIATSPGAEATSDFPTITVSPDVPDMVTSQVTSSGTDTSITIPTLTLSSG 11427

Query: 934   GPGQRRESSSSAERQWVESSPKPMVSLLGSGRPTGSPLSAEFSGT-----------RKDS 982
              P       + +E     + P   VS   S   T   +S+    T             ++
Sbjct: 11428 EPETTTSFITYSETHTSSAIPTLPVSPGASKMLTSLVISSGTDSTTTFPTLTETPYEPET 11487

Query: 983   PVLSCFPPSELQ------APFHSHELSLAEPPDSLAPPSSQAFLGFGTAPVGSGLPPEED 1036
               +    P+E         P  SH  S    P ++  P  +A     T  +    P   D
Sbjct: 11488 TAIQLIHPAETNTMVPRTTPKFSHSKSDTTLPVAITSPGPEASSAVSTTTIS---PDMSD 11544

Query: 1037  LGALLANSHGASPTPSIP 1054
             L   L  S G   + + P
Sbjct: 11545 LVTSLVPSSGTDTSTTFP 11562



 Score = 41.2 bits (95), Expect = 0.007
 Identities = 94/421 (22%), Positives = 156/421 (37%), Gaps = 43/421 (10%)

Query: 809  FPSPADVKETMTPGYPQDLDIIDGRILSSKESMCSTPAFPVSPETPYVKTALRHPPF--- 865
            +PSP  VKET  P  P  L  +     +S   + +T    + P    V + L   P    
Sbjct: 7675 WPSPPFVKETSPPSSPLSLPAV-----TSPHPVSTTFLAHIPPSPLPVTSLLTSGPATTT 7729

Query: 866  ----SPPEPPLSSPASQHKGGREPRSCPETLTH--AVGMSESPIGPKSTMLRADASSTPS 919
                +  EP  SS +S      E  +  +   H  AV  S +  G       +   S  S
Sbjct: 7730 DILGTSTEPGTSSSSSLSTTSHERLTTYKDTAHTEAVHPSTNTGGTNVATTSSGYKSQSS 7789

Query: 920  FQQAFASSCTISSNGPGQRRESSSS-AERQWVESSPKPMVSLLGSGRPTGSPLSAEFSGT 978
                 +  CT S+ G      S+ +  E + +++    + S L  G    S      SGT
Sbjct: 7790 VLADSSPMCTTSTMGDTSVLTSTPAFLETRRIQTE---LASSLTPGLRESSGSEGTSSGT 7846

Query: 979  RKDSPVLSCFPPSELQAPFHSHELSLAEPPDSLAPP--SSQAFLGFGTAPVGSGLPPEED 1036
             K S VLS  P             S+  P  S   P  S++    F T+PV +      +
Sbjct: 7847 -KMSTVLSKVPTGATTEISKEDVTSIPGPAQSTISPDISTRTVSWFSTSPVMT------E 7899

Query: 1037 LGALLANSHGA---SPTPSIPLTATGAADNGFLSHNFLTVAPGHSSHHSPGLQGQGVTLP 1093
               +  N+H +   + T       T +  +  ++H+ ++    HS   +   +G      
Sbjct: 7900 SAEITMNTHTSPLGATTQGTSTLDTSSTTSLTMTHSTISQGFSHSQMSTLMRRGPEDVSW 7959

Query: 1094 GQPPLPEKKRASEG-DRSLGSVSPSSSGFSSPHSGSTISIPFPNVLPD-FSKASE----A 1147
              PPL EK R S     S  + SPS    + P S S+  +P  ++L    +K ++    +
Sbjct: 7960 MSPPLLEKTRPSFSLMSSPATTSPSPVSSTLPESISSSPLPVTSLLTSGLAKTTDMLHKS 8019

Query: 1148 ASPLPDSPG-------DKLVIVKFVQDTSKFWYKADISREQAIAMLKDKEPGSFIVRDSH 1200
            + P+ +SP        + L   +   DT K    ++ +           E  SF++ DS 
Sbjct: 8020 SEPVTNSPANLSSTSVEILATSEVTTDTEKTHPSSNRTVTDVGTSSSGHESTSFVLADSQ 8079

Query: 1201 S 1201
            +
Sbjct: 8080 T 8080



 Score = 35.4 bits (80), Expect = 0.40
 Identities = 60/254 (23%), Positives = 85/254 (33%), Gaps = 18/254 (7%)

Query: 889  PETLTHAVGMSESPIGPKSTMLRADASSTPSFQQAFASSCTISSNGPGQRRESSSSAERQ 948
            P T T    +  S  G +S       S TP       ++ T+                R 
Sbjct: 8347 PSTHTAVTNVRTSISGHESQSSVLSDSETPKATSPMGTTYTMGETSVSISTSDFFETSRI 8406

Query: 949  WVESSPKPMVSLLGSGRPTGSPLSAEFSGTRKDSPVLSCFPPSELQAP-----FHSHELS 1003
             +E    P  SL    R T S  S   S   + S VLS  P              S   S
Sbjct: 8407 QIE----PTSSLTSGLRETSS--SERISSATEGSTVLSEVPSGATTEVSRTEVISSRGTS 8460

Query: 1004 LAEPPDSLAPP--SSQAFLGFGTAPVGSGLPPEEDLGALLANSHGASPTPSIPLTATGAA 1061
            ++ P      P  S++A     T+P+ +     E    +   S GA+   ++ L  +   
Sbjct: 8461 MSGPDQFTISPDISTEAITRLSTSPIMT--ESAESAITIETGSPGATSEGTLTLDTSTTT 8518

Query: 1062 DNGFLSHNFLTVAPGHSSHHSPGLQGQGVTLPGQPPLPEKKRASEGDRSLGSVSPSSSGF 1121
               F S    T +PG S      L  +       P LP  + AS    SL S + +S+ F
Sbjct: 8519 ---FWSGTHSTASPGFSHSEMTTLMSRTPGDVPWPSLPSVEEASSVSSSLSSPAMTSTSF 8575

Query: 1122 SSPHSGSTISIPFP 1135
             S    S  S P P
Sbjct: 8576 FSTLPESISSSPHP 8589


>gi|20143482 melanoma antigen family E, 1 [Homo sapiens]
          Length = 957

 Score = 52.0 bits (123), Expect = 4e-06
 Identities = 93/386 (24%), Positives = 142/386 (36%), Gaps = 45/386 (11%)

Query: 794  AWGKAGVDYAPNLPPFPSPADVKETMTPGYPQDLDIIDGRILSSKESMCSTPAFPVSPET 853
            +WG+     AP LP     ADV  +  P  P D  I+ G   S   S    P     P T
Sbjct: 24   SWGEMQAPNAPGLP-----ADVPGSDVPQGPSDSQILQGLCASEGPSTSVLPTSAEGPST 78

Query: 854  PYVKTALRHPPFSPPEPPLSS--------PASQHKGGREPRSCPETLTHAVGMSESPIGP 905
             +V   +     +  +P +S           S+      P +  + L  +V ++ S    
Sbjct: 79   -FVPPTISEASSASGQPTISEGPGTSVLPTPSEGLSTSGPPTISKGLCTSVTLAASE--G 135

Query: 906  KSTMLRADASSTPSFQQAFASSCTISSNGPGQRRESSSSAERQWVESSPK---------- 955
            ++T     +S  PS      +S   S++ P    E +S++        P           
Sbjct: 136  RNTSRPPTSSEEPSTSVPPTASEVPSTSLPPTPGEGTSTSVPPTAYEGPSTSVVPTPDEG 195

Query: 956  PMVSLL---GSGRPTGSPLSAEFSGTRKDSPVLSCFPPSELQAPFHSHELSLAEPPDSLA 1012
            P  S+L   G G  T  PL+A   G            PS    P  +  LS   PP    
Sbjct: 196  PSTSVLPTPGEGPGTSVPLAAT-EGLSTSVQATPDEGPSTSVPPTATEGLSTPVPPTRDE 254

Query: 1013 PPSSQAFLGFGTAPVGSGLPPEEDLGAL-LANSHGASPTPSIPLTATGAADNGFLSHNFL 1071
             PS+      G  P  S LP   D  ++ L  + G   + S+P TAT       LS +  
Sbjct: 255  GPSTSVPATPGEGPSTSVLPAASDGQSISLVPTRGKGSSTSVPPTATEG-----LSTSVQ 309

Query: 1072 TVAPGHSSHHSPGLQGQGVTLPGQPPLPEKKRASEGDRSLGSVSPSSSGFSSPHSGSTIS 1131
              A   SS   P   G G++    PP   ++ ++    + G   PS+S    P  G + S
Sbjct: 310  PTAGEGSSTSVPPTPGGGLS-TSVPPTATEELSTSVPPTPGE-GPSTSVLPIPGEGLSTS 367

Query: 1132 IPFPNVLPDFSKASEAASPLPDSPGD 1157
            +P     P  S  S+ +  +P +PG+
Sbjct: 368  VP-----PTASDGSDTS--VPPTPGE 386



 Score = 37.7 bits (86), Expect = 0.081
 Identities = 74/298 (24%), Positives = 97/298 (32%), Gaps = 40/298 (13%)

Query: 481 EMPHHDLHSVDSLGTLSSSEGPQSAHLGPFTCHKSSQNSLLSDGFGSNVGEDPQGTLVPD 540
           E+P   L      GT  S+  P +A+ GP T    + +   S       GE P GT VP 
Sbjct: 158 EVPSTSLPPTPGEGT--STSVPPTAYEGPSTSVVPTPDEGPSTSVLPTPGEGP-GTSVPL 214

Query: 541 LGLGMDGPYERERTFGSREPKQPQPLLRKPSVSAQMQAYGQSSYSTQTWVRQQQMVVAHQ 600
                +G     +      P    P      +S  +        ST       +      
Sbjct: 215 AAT--EGLSTSVQATPDEGPSTSVPPTATEGLSTPVPPTRDEGPSTSVPATPGEGPSTSV 272

Query: 601 YSFAPDGEARLVSRCPADNPGLVQAQPRVPLTPTRGTSSRVAVQRGVGSGPHPPDTQQPS 660
              A DG++  +S  P    G   +   VP T T G S+ V    G GS    P T    
Sbjct: 273 LPAASDGQS--ISLVPTRGKG---SSTSVPPTATEGLSTSVQPTAGEGSSTSVPPTPGGG 327

Query: 661 PSKAFKPRFPGDQVVN-----GAGPELSTGPSPGS------PTLDIDQSIEQLNRLILEL 709
            S +  P    +   +     G GP  S  P PG       P    D S           
Sbjct: 328 LSTSVPPTATEELSTSVPPTPGEGPSTSVLPIPGEGLSTSVPPTASDGS----------- 376

Query: 710 DPTFEPIPTHMNALGSQANGSVSPDSVGGGLRASSRLPDTGEGPSRATGRQGSSAEQP 767
           D +  P P      G  A+  V P +  G    SS LP+ GEGPS       S    P
Sbjct: 377 DTSVPPTP------GEGASTLVQPTAPDGP--GSSVLPNPGEGPSTLFSSSASVDRNP 426


>gi|54860079 nadrin isoform 1 [Homo sapiens]
          Length = 881

 Score = 51.6 bits (122), Expect = 5e-06
 Identities = 77/305 (25%), Positives = 110/305 (36%), Gaps = 36/305 (11%)

Query: 864  PFSPPEPPLSSPASQHKGGREPRSCPETLTHAVGMSE-SPIGPKSTMLRA---------D 913
            P  P  PP SS A    GG    S    L       + SP  PK  +  A          
Sbjct: 537  PAGPEPPPQSSRAESSSGGGTVPSSAGILEQGPSPGDGSPPKPKDPVSAAVPAPGRNNSQ 596

Query: 914  ASSTPSFQQAFASSCTISSNGPGQRRESSSSAERQWVESSPKPMVSLLGSGRPTGSPLSA 973
             +S  +  QA A S  +S   P      S    R+ V+  P P     G+  P G P   
Sbjct: 597  IASGQNQPQAAAGSHQLSMGQPHNAAGPSPHTLRRAVKK-PAPAPPKPGNP-PPGHPGGQ 654

Query: 974  EFSGTRKDSPVLSCFPPSELQAPFHSHELSLAEPPDSLAPPSSQAFLGFGTAPVGSGLPP 1033
              SGT +  P LS  PP+   +P   H     +PP   + PS  +          S L P
Sbjct: 655  SSSGTSQHPPSLSPKPPTRSPSPPTQH---TGQPPGQPSAPSQLS----APRRYSSSLSP 707

Query: 1034 EEDLGALLANSH--GASPTPSIPLTATGAADNGFLSHNFLTVAPGHSSHHSPGLQGQGVT 1091
                  + A +H     PT + PL  T     G    N + +   H          Q  T
Sbjct: 708  ------IQAPNHPPPQPPTQATPLMHTKPNSQG--PPNPMALPSEHGLEQPSHTPPQTPT 759

Query: 1092 LPGQPPLPEKKRASEGDRSLGSVSPSSSGFSSPHSGSTISIPFPNVLPDFSKASEAASPL 1151
             P  PPL ++  +    ++L   +P +   + PH+G   ++P P  +P   +   +  P 
Sbjct: 760  PPSTPPLGKQNPSLPAPQTLAGGNPET---AQPHAG---TLPRPRPVPK-PRNRPSVPPP 812

Query: 1152 PDSPG 1156
            P  PG
Sbjct: 813  PQPPG 817



 Score = 49.3 bits (116), Expect = 3e-05
 Identities = 97/373 (26%), Positives = 130/373 (34%), Gaps = 58/373 (15%)

Query: 630 PLTPTRGTSSRVAVQRGVGSGPHPPDTQQPSPSKAFKPRFPGDQVVNGAGPELSTGPSPG 689
           PL PT G++        V +GP PP    P  S+A +    G  V + AG  L  GPSPG
Sbjct: 526 PLPPTDGSTV-------VPAGPEPP----PQSSRA-ESSSGGGTVPSSAGI-LEQGPSPG 572

Query: 690 SPTLDIDQSIEQLNRLILELDPTFEPIPTHMNALGSQANGSVSPDSVGGGLRASSRLPDT 749
             +    +            DP    +P         A+G   P +  G  + S   P  
Sbjct: 573 DGSPPKPK------------DPVSAAVPAPGRNNSQIASGQNQPQAAAGSHQLSMGQPHN 620

Query: 750 GEGPSRATGRQGSSAEQPLGGRLRKLSLGQYDNDAGGQLPFSKCAWGKAGVDYAPNLPP- 808
             GPS  T R+      P   +      G      GGQ   S     +     +P  P  
Sbjct: 621 AAGPSPHTLRRAVKKPAPAPPKPGNPPPGH----PGGQ---SSSGTSQHPPSLSPKPPTR 673

Query: 809 FPSPADVKETMTPGYPQDLDIIDG-RILSSKESMCSTPAFPVSPETPYVKTALRH--PPF 865
            PSP        PG P     +   R  SS  S    P  P  P+ P   T L H  P  
Sbjct: 674 SPSPPTQHTGQPPGQPSAPSQLSAPRRYSSSLSPIQAPNHP-PPQPPTQATPLMHTKPNS 732

Query: 866 SPPEPPLSSPASQHKGGREPRSCPETLTHAVGMSESPIGPKSTMLRAD---ASSTPSFQQ 922
             P  P++ P S+H   +   + P+T T     S  P+G ++  L A    A   P   Q
Sbjct: 733 QGPPNPMALP-SEHGLEQPSHTPPQTPTPP---STPPLGKQNPSLPAPQTLAGGNPETAQ 788

Query: 923 AFASSCTISSNGPGQRRESSSSAERQWVESSPKPM------VSLLGSGRPTGSPLSAEFS 976
             A +       P  R   S       V   P+P        S L +  PT S +  + S
Sbjct: 789 PHAGTLPRPRPVPKPRNRPS-------VPPPPQPPGVHSAGDSSLTNTAPTASKIVTD-S 840

Query: 977 GTRKDSPVLSCFP 989
            +R   P  S FP
Sbjct: 841 NSRVSEPHRSIFP 853


>gi|239743293 PREDICTED: mucin 12 [Homo sapiens]
          Length = 5478

 Score = 51.2 bits (121), Expect = 7e-06
 Identities = 128/578 (22%), Positives = 191/578 (33%), Gaps = 73/578 (12%)

Query: 620  PGLVQAQPRV---PLTPTRGTSSRVAVQRGVGSGPHPPDTQQPSPSKAFKPRFPGDQVVN 676
            PGL +A       P +PT   S       GVG       T +  P        P      
Sbjct: 2321 PGLSEASTTFYSSPRSPTTTLSPASMTSLGVGE---ESTTSRSQPGSTHSTVSPASTTTP 2377

Query: 677  GAGPELST--GPSPGSPTLDIDQSIEQLNRLILELDPTF---EPIPTHMNALGSQANGSV 731
            G   E +T    SPGS    +       +  +   +PT     P  TH       +  S 
Sbjct: 2378 GLSEESTTVYSSSPGSTETTVFPRTPTTS--VRGEEPTTFHSRPASTHTTLFTEDSTTSG 2435

Query: 732  ----------SPDSVGGGLRASSRLPDTGEGPSRATGRQGSSAEQPLGGRLRKLSLGQYD 781
                      SP S   GL A+    D GE  +      GS+         R  + G   
Sbjct: 2436 LTEESTAFPGSPASTQTGLPATLTTADLGEESTTFPSSSGSTGTTL--SPARSTTSGLVG 2493

Query: 782  NDAGGQL-PFSKCAWGKAGVDYAPNLPP-----FPSPADVKETMTPGYPQDLDIIDGRIL 835
                 +L P S       G    P+L       + SP     T++P       + +    
Sbjct: 2494 ESTPSRLSPSSTETTTLPGSPTTPSLSEKSTTFYTSPRSPDATLSPATTTSSGVSEESST 2553

Query: 836  S-SKESMCSTPAFPVSPETPYVKTALRHPPFSPPEPPLSS----PASQHKGGREPRSCPE 890
            S S+     T AFP S  TP +    RH   S   P  +     PAS    G    S   
Sbjct: 2554 SHSQPGSTHTTAFPDSTTTPGLS---RHSTTSHSSPGSTDTTLLPASTTTSGPSQES--- 2607

Query: 891  TLTHAV-GMSESPIGPKSTMLRADASSTPSFQQAFASSCTISSNGPGQRRESSSSAERQW 949
            T +H+  G +++ + P ST   +    + +F  +  S+ T             S+     
Sbjct: 2608 TTSHSSPGSTDTALSPGSTTALSFGQESTTFHSSPGSTHTTLF--------PDSTTSSGI 2659

Query: 950  VESSPKPMVSLLGSGRPTGSPLSAEFSGTRKDSPVLSCFPPSELQAPFHSHELSLAEPPD 1009
            VE+S + + S  GS R T SP S+   G + +S      P S    P        + P  
Sbjct: 2660 VEASTR-VHSSTGSPRTTLSPASSTSPGLQGESTTFQTHPASTHTTP--------SPPST 2710

Query: 1010 SLAP----------PSSQAFLGFGTAPVGSGLPPEEDLGALLANSHGASPTPSIPLTA-T 1058
            + AP          P S     F  +   SG   +  +     ++ G +P+ +   T+  
Sbjct: 2711 ATAPVEESTTYHRSPGSTPTTHFPASSTTSGHSEKSTIFHSSPDASGTTPSSAHSTTSGR 2770

Query: 1059 GAADNGFLSHNFLTVAPGHSSHHSPGLQGQGVTLPGQPPLPEKKRASEGDRSLGSVSPSS 1118
            G +    +S     +     S  +PGL     T    P  P    +     SLG    S+
Sbjct: 2771 GESTTSRISPGSTEITTLPGSTTTPGLSEASTTFYSSPRSPTTTLSPASMTSLGVGEEST 2830

Query: 1119 SGFSSPHSGSTISIPFPNVLPDFSKASEAASPLPDSPG 1156
            +  S P S  +   P     P  S+  E+ +    SPG
Sbjct: 2831 TSRSQPGSTHSTVSPASTTTPGLSE--ESTTVYSSSPG 2866



 Score = 50.8 bits (120), Expect = 9e-06
 Identities = 169/810 (20%), Positives = 261/810 (32%), Gaps = 130/810 (16%)

Query: 396  STASARTDKTEERLAPG--TRRGLSAQEKAELDQLLSGFGLEDPGSSLKEMTDARSKYSG 453
            +T+   +  TE    PG  T  GLS +         S      P S+    +   S+ S 
Sbjct: 3221 TTSPISSGSTETTALPGSTTTAGLSEKSTTFYSSPRSPDTTLSPASTT---SSGVSEEST 3277

Query: 454  TRHVVPAQVHVNGDAALKDRETDILDDEMPHHDLHSVDSL----GTLSSSEGPQSA--HL 507
            T H  P   H               +    H    S D+      T +SS GP+S   H 
Sbjct: 3278 TSHSRPGSTHTTAFPGSTTMPGVSQESTASHSSPGSTDTTLSPGSTTASSLGPESTTFHS 3337

Query: 508  GPFTCHKSSQNSLLSDG------------FGSNVGEDPQGTLVPDLGLGMDGPYERERTF 555
            GP     S++ +LL D               S+ G  P  TL P       G     +++
Sbjct: 3338 GP----GSTETTLLPDNTTASGLLEASTPVHSSTGS-PHTTLSPAGSTTRQGESTTFQSW 3392

Query: 556  -GSREPKQPQPLLRKPSVSAQMQAYGQSSYSTQTWVRQQQMVVAHQYSFAPDGEARLVSR 614
              S++     P      V     ++G  S +  T         A   +     E+  V  
Sbjct: 3393 PNSKDTTPAPPTTTSAFVELSTTSHGSPSSTPTTHFS------ASSTTLGRSEESTTVHS 3446

Query: 615  CPADNPGLVQAQPRVPLTPTRGTSSRVAVQRGVGSGPHPPDTQQPSPSKAFKPRFPGDQV 674
             P        A    P +P R T+S +  +           T   SP       FP    
Sbjct: 3447 SPV-------ATATTP-SPARSTTSGLVEES---------TTYHSSPGSTQTMHFPESDT 3489

Query: 675  VNGAGPELSTGPSPGSPTLDIDQSIEQLNRLILELDPTFEPIPTHMNALGSQANGSVSPD 734
             +G G E +T  S  + T+    S       ++E     EP   H +             
Sbjct: 3490 TSGRGEESTTSHSSTTHTIS---SAPSTTSALVE-----EPTSYHSSP------------ 3529

Query: 735  SVGGGLRASSRLPDTGEGPSRATGRQGSSAEQPLGGRLRKLSLGQYDNDAGGQLPFSKCA 794
                G  A++  PD+     R+     S + Q   G +  L      +   G+   S  +
Sbjct: 3530 ----GSTATTHFPDSSTTSGRSEESTASHSSQDATGTI-VLPARSTTSVLLGESTTSPIS 3584

Query: 795  WGKAGVDYAPNLPPFP-----------SPADVKETMTPGYPQDLDIIDGRILS-SKESMC 842
             G       P     P           SP     T++P       + +    S S+    
Sbjct: 3585 SGSMETTALPGSTTTPGLSEKSTTFHSSPRSPATTLSPASTTSSGVSEESTTSHSRPGST 3644

Query: 843  STPAFPVSPETPYVKTALRHPPFSPPEPPLSS----PASQHKGGREPRSCPETLTHAV-G 897
             T AFP S  TP +    RH   S   P  +     PAS    G    S   T +H+  G
Sbjct: 3645 HTTAFPDSTTTPGLS---RHSTTSHSSPGSTDTTLLPASTTTSGSSQES---TTSHSSSG 3698

Query: 898  MSESPIGPKSTMLRADASSTPSFQQAFASSCTISSNGPGQRRESSSSAERQWVESSPKPM 957
             +++ + P ST   +    + +F  +  S+ T             S+     VE+S + +
Sbjct: 3699 STDTALSPGSTTALSFGQESTTFHSSPGSTHTTLF--------PDSTTSSGIVEASTR-V 3749

Query: 958  VSLLGSGRPTGSPLSAEFSGTRKDSPVLSCFPPSELQAPFHSHELSLAEPPDSLAP---- 1013
             S  GS R T SP S+   G + +S      P S    P        + P  + AP    
Sbjct: 3750 HSSTGSPRTTLSPASSTSPGLQGESTAFQTHPASTHTTP--------SPPSTATAPVEES 3801

Query: 1014 ------PSSQAFLGFGTAPVGSGLPPEEDLGALLANSHGASPTPSIPLTA-TGAADNGFL 1066
                  P S     F  +   SG   +  +     ++ G +P+ +   T+  G +    +
Sbjct: 3802 TTYHRSPGSTPTTHFPASSTTSGHSEKSTIFHSSPDASGTTPSSAHSTTSGRGESTTSRI 3861

Query: 1067 SHNFLTVAPGHSSHHSPGLQGQGVTLPGQPPLPEKKRASEGDRSLGSVSPSSSGFSSPHS 1126
            S     +     S  +PGL     T    P  P    +     SLG    S++  S P S
Sbjct: 3862 SPGSTEITTLPGSTTTPGLSEASTTFYSSPRSPTTTLSPASMTSLGVGEESTTSRSQPGS 3921

Query: 1127 GSTISIPFPNVLPDFSKASEAASPLPDSPG 1156
              +   P     P  S+  E+ +    SPG
Sbjct: 3922 THSTVSPASTTTPGLSE--ESTTVYSSSPG 3949



 Score = 48.9 bits (115), Expect = 4e-05
 Identities = 119/543 (21%), Positives = 177/543 (32%), Gaps = 69/543 (12%)

Query: 630  PLTPTRGTSSRVAVQ----RGVGSG-PHPPDTQQPSPSKAFKPRFPGDQVVNGAGPELST 684
            P T + G+ S +       R   SG      T   SP       FP     +G G E +T
Sbjct: 800  PSTTSHGSPSSIPTTHISARSTTSGLVEESTTYHSSPGSTQTMHFPESDTTSGRGEESTT 859

Query: 685  GPSPGSPTLDIDQSIEQLNRLILELDPTFEPIPTHMNALGSQANGSVSPDSVGGGLRASS 744
              S  + T+    S       ++E     EP   H +                 G  A++
Sbjct: 860  SHSSTTHTI---SSAPSTTSALVE-----EPTSYHSSP----------------GSTATT 895

Query: 745  RLPDTGEGPSRATGRQGSSAEQPLGGRLRKLSLGQYDNDAGGQLPFSKCAWGKAGVDYAP 804
              PD+     R+     S + Q   G +  L      +   G+   S  + G       P
Sbjct: 896  HFPDSSTTSGRSEESTASHSSQDATGTI-VLPARSTTSVLLGESTTSPISSGSMETTALP 954

Query: 805  NLPPFP-----------SPADVKETMTPGYPQDLDIIDGRILS-SKESMCSTPAFPVSPE 852
                 P           SP     T++P       + +    S S+     T AFP S  
Sbjct: 955  GSTTTPGLSERSTTFHSSPRSPATTLSPASTTSSGVSEESTTSRSRPGSTHTTAFPDSTT 1014

Query: 853  TPYVKTALRHPPFSPPEPPLSS----PASQHKGGREPRSCPETLTHAVGMSESPIGPKST 908
            TP +    RH   S   P  +     PAS    G    S           S S  G   T
Sbjct: 1015 TPGLS---RHSTTSHSSPGSTDTTLLPASTTTSGPSQEST---------TSHSSSGSTDT 1062

Query: 909  MLRADASSTPSFQQAFASSCTISSNGPGQRRES---SSSAERQWVESSPKPMVSLLGSGR 965
             L   +++  SF Q    S T  SN PG    +    S+     VE+S + + S  GS R
Sbjct: 1063 ALSPGSTTALSFGQ---ESTTFHSN-PGSTHTTLFPDSTTSSGIVEASTR-VHSSTGSPR 1117

Query: 966  PTGSPLSAEFSGTRKDSPVLSCFPPS--ELQAPFHSHELSLAEPPDSLAPPSSQAFLGFG 1023
             T SP S+   G + +S      P S     +P  +    + E       P S     F 
Sbjct: 1118 TTLSPASSTSPGLQGESTAFQTHPASTHTTPSPPSTATAPVEESTTYHRSPGSTPTTHFP 1177

Query: 1024 TAPVGSGLPPEEDLGALLANSHGASPTPSIPLTA-TGAADNGFLSHNFLTVAPGHSSHHS 1082
             +   SG   +  +     ++ G +P+ +   T+  G +    +S     +     S  +
Sbjct: 1178 ASSTTSGHSEKSTIFHSSPDASGTTPSSAHSTTSGRGESTTSRISPGSTEITTLPGSTTT 1237

Query: 1083 PGLQGQGVTLPGQPPLPEKKRASEGDRSLGSVSPSSSGFSSPHSGSTISIPFPNVLPDFS 1142
            PGL     T    P  P    +     SLG    S++  S P S  +   P     P  S
Sbjct: 1238 PGLSEASTTFYSSPRSPTTTLSPASMTSLGVGEESTTSRSQPGSTHSTVSPASTTTPGLS 1297

Query: 1143 KAS 1145
            + S
Sbjct: 1298 EES 1300



 Score = 48.1 bits (113), Expect = 6e-05
 Identities = 175/815 (21%), Positives = 264/815 (32%), Gaps = 104/815 (12%)

Query: 369  GGPQAIPATNSPDHSDHTLSVSSDSGHSTASARTDKTEERLAPGTRRGLSAQEKAELDQL 428
            G P + P T+    S  TL  S +S    +S     T    A  T  GL  +  A     
Sbjct: 1861 GSPSSTPTTHF-SASSTTLGRSEESTTVHSSPVATATTPSPARSTTSGLVEESTAYHSSP 1919

Query: 429  LSGFGLEDPGSSLKE--MTDARSKYSGTRHVVPAQVHVNGDAALKDRETDILDDEMPHHD 486
             S   +  P SS       ++R+ +S T H + +       +AL +  T           
Sbjct: 1920 GSTQTMHFPESSTASGRSEESRTSHSSTTHTISSPPSTT--SALVEEPTSYHSSPGSTAT 1977

Query: 487  LHSVDSLGTLSSSEGPQSAHLGPFTCH------KSSQNSLLSDGFGSNVGEDPQGTLVPD 540
             H  DS  T   SE   ++H             +S+ + LL +   S +      T    
Sbjct: 1978 THFPDSSTTSGRSEESTASHSSQDATGTIVLPARSTTSVLLGESTTSPISSGSMETTALP 2037

Query: 541  LGLGMDGPYERERTFGSREPKQPQPLLRKPSVSAQMQAYGQSSYSTQTWVRQQQMVVAHQ 600
                  G  E+  TF S  P+ P   L   S ++     G S  ST +  R       H 
Sbjct: 2038 GSTTTPGLSEKSTTFHS-SPRSPATTLSPASTTSS----GVSEESTTSHSRPGS---THT 2089

Query: 601  YSFAPDGEARLVSRCPADNPGLVQAQPRVPLTPTRGTSSRVAVQRGVGSGPHPPDTQQPS 660
             +F PD             PGL +       +P    ++ +              T   S
Sbjct: 2090 TAF-PDSTT---------TPGLSRHSTTSHSSPGSTDTTLLPASTTTSGPSQESTTSHSS 2139

Query: 661  PSKAFKPRFPGDQVVNGAGPELST-GPSPGSPTLDIDQSIEQLNRLILELDPTFEPIPTH 719
            P        PG       G E +T   SPGS    +       + ++           T 
Sbjct: 2140 PGSTDTALSPGSTTALSFGQESTTFHSSPGSTHTTLFPDSTTSSGIV--------EASTR 2191

Query: 720  MNALGSQANGSVSP-DSVGGGLRASSRLPDTGEGPSRATGRQGSSAEQPLGGRLRKLSLG 778
            +++       ++SP  S   GL+  S    T    +  T    S+A  P+          
Sbjct: 2192 VHSSTGSPRTTLSPASSTSPGLQGESTAFQTHPASTHTTPSPPSTATAPVEESTTY---- 2247

Query: 779  QYDNDAGGQLPFSKCAWGKAGVDYAPNLPPFPSPADVKETMTPGYPQDLDIIDGRILSSK 838
               + + G  P +          ++     F S  D   T TP          G   +S+
Sbjct: 2248 ---HRSPGSTPTTHFPASSTTSGHSEKSTIFHSSPDASGT-TPSSAHSTTSGRGESTTSR 2303

Query: 839  ESMCSTPAFPVSPETPYVKTALRHPPFSPPEPPLSSPASQHKGGREPRSCPETLTHAVGM 898
                      +SP +  + T     P S   P LS  ++       PRS   TL+ A  M
Sbjct: 2304 ----------ISPGSTEITTL----PGSTTTPGLSEASTTFYSS--PRSPTTTLSPA-SM 2346

Query: 899  SESPIGPKSTMLRADASSTPSFQQAFASSCTISSNGPGQRRESSSSAERQWVESSPKPMV 958
            +   +G +ST  R+   ST S      +    S+  PG   ES++        SSP    
Sbjct: 2347 TSLGVGEESTTSRSQPGSTHS------TVSPASTTTPGLSEESTTV-----YSSSP---- 2391

Query: 959  SLLGSGRPTGSPLSAEFSGTRKDSPVLSCFPPSELQAPFHSHELSLAEPPDSLAPPSSQA 1018
               GS   T  P +   S   ++       P S     F     +     +S A P S A
Sbjct: 2392 ---GSTETTVFPRTPTTSVRGEEPTTFHSRPASTHTTLFTEDSTTSGLTEESTAFPGSPA 2448

Query: 1019 FLGFGTAPVGSGLPPE---EDLG---ALLANSHGASPTPSIPLTATGAADNGFLSHNFL- 1071
                      +GLP      DLG       +S G++ T   P  +T +   G  + + L 
Sbjct: 2449 -------STQTGLPATLTTADLGEESTTFPSSSGSTGTTLSPARSTTSGLVGESTPSRLS 2501

Query: 1072 ------TVAPGHSSHHSPGLQGQGVTLPGQPPLPEKKRASEGDRSLGSVSPSSSGFSSPH 1125
                  T  PG  S  +P L  +  T    P  P+   +     S G    SS+  S P 
Sbjct: 2502 PSSTETTTLPG--SPTTPSLSEKSTTFYTSPRSPDATLSPATTTSSGVSEESSTSHSQPG 2559

Query: 1126 SGSTISIPFPNVLPDFSKASEAASPLPDSPGDKLV 1160
            S  T + P     P  S+ S  +   P S    L+
Sbjct: 2560 STHTTAFPDSTTTPGLSRHSTTSHSSPGSTDTTLL 2594



 Score = 44.3 bits (103), Expect = 9e-04
 Identities = 90/338 (26%), Positives = 125/338 (36%), Gaps = 62/338 (18%)

Query: 843  STPAFPVSPETP-------YVKTALRHPPFSPPEPPLSSPASQHKGGREPRSCPETLTHA 895
            STP+  V   TP          TAL   P S  +P LS  ++       PRS P+T    
Sbjct: 599  STPSVLVGDSTPSPISSGSMETTAL---PGSTTKPGLSEKSTTFYSS--PRS-PDTTHLP 652

Query: 896  VGMSESPIGPKSTMLRADASSTPSFQQAFASSCTISSNGPGQRRESSSSAERQWVESSPK 955
              M+ S +  +ST   +   ST +   AF  S T+    PG  +ES++S       SSP 
Sbjct: 653  ASMTSSGVSEESTTSHSRPGSTHT--TAFPGSTTM----PGLSQESTAS------HSSPG 700

Query: 956  PMVSLLGSGRPTGSPLSAEFS--GTRKDSPVLSCFPPS-------ELQAPFHSHELSLAE 1006
            P  + L  G  T S L  E++   +R  S   +  P +       E   P HS   S   
Sbjct: 701  PTDTTLSPGSTTASSLGPEYTTFHSRPGSTETTLLPDNTTASGLLEASMPVHS---STRS 757

Query: 1007 PPDSLAPPSSQAFLGFGTAPVGSGLPPEEDLGALLANSHGASPTPSIPLTATGAADNGFL 1066
            P  +L+P  S    G  T       P  +D              P+ P T +   +    
Sbjct: 758  PHTTLSPAGSTTRQGEST--TFHSWPSSKD------------TRPAPPTTTSAFVEPSTT 803

Query: 1067 SHNFLTVAP-GHSSHHS--PGLQGQGVTLPGQP------PLPEKKRAS-EGDRSLGSVSP 1116
            SH   +  P  H S  S   GL  +  T    P        PE    S  G+ S  S S 
Sbjct: 804  SHGSPSSIPTTHISARSTTSGLVEESTTYHSSPGSTQTMHFPESDTTSGRGEESTTSHSS 863

Query: 1117 SSSGFSSPHSGSTISIPFPNVLPDFSKASEAASPLPDS 1154
            ++   SS  S ++  +  P      S  S A +  PDS
Sbjct: 864  TTHTISSAPSTTSALVEEPTSYHS-SPGSTATTHFPDS 900



 Score = 44.3 bits (103), Expect = 9e-04
 Identities = 121/530 (22%), Positives = 180/530 (33%), Gaps = 69/530 (13%)

Query: 656  TQQPSPSKAFKPRFPGDQVVNGAGPELSTGPSPGSPTLDIDQSIEQLNRLILELDPTFEP 715
            T   SP        P     +G+  E +T  S    T   D ++   +   L    +F  
Sbjct: 3664 TSHSSPGSTDTTLLPASTTTSGSSQESTTSHSSSGST---DTALSPGSTTAL----SFGQ 3716

Query: 716  IPTHMNALGSQANGSVSPDSV--GGGLRASSRLPDTGEGPSRATGRQGSSAEQPLGGRLR 773
              T  ++     + ++ PDS    G + AS+R+  +  G  R T    SS    L G   
Sbjct: 3717 ESTTFHSSPGSTHTTLFPDSTTSSGIVEASTRV-HSSTGSPRTTLSPASSTSPGLQGEST 3775

Query: 774  KLSLGQYDNDAGGQLPFSKCAWGKAGVDYAPNLPPFPSPADVKETMTPGYPQDLDII--- 830
                           P +  A  +    Y  +    P+      + T G+ +   I    
Sbjct: 3776 AFQTHPASTHTTPSPPSTATAPVEESTTYHRSPGSTPTTHFPASSTTSGHSEKSTIFHSS 3835

Query: 831  ---DGRILSSKESMCSTPAFPVSPETPYVKTALRHPPFSPPEPPLSSPASQHKGGREPRS 887
                G   SS  S  S      +       T +   P S   P LS  ++       PRS
Sbjct: 3836 PDASGTTPSSAHSTTSGRGESTTSRISPGSTEITTLPGSTTTPGLSEASTTFYSS--PRS 3893

Query: 888  CPETLTHAVGMSESPIGPKSTMLRADASSTPSFQQAFASSCTISSNGPGQRRESSSSAER 947
               TL+ A  M+   +G +ST  R+   ST S      +    S+  PG   ES++    
Sbjct: 3894 PTTTLSPA-SMTSLGVGEESTTSRSQPGSTHS------TVSPASTTTPGLSEESTTV--- 3943

Query: 948  QWVESSPKPMVSLLGSGRPTGSPLSAEFSGTRKDSPVLSCFPPSELQAPFHSHELSLAEP 1007
                SSP       GS   T  P S   S  R++       P S     F     +    
Sbjct: 3944 --YSSSP-------GSTETTVFPRSTTTSVRREEPTTFHSRPASTHTTLFTEDSTTSGLT 3994

Query: 1008 PDSLAPPSSQAFLGFGTAPVGSGLPPE---EDLG---ALLANSHGASPTPSIPLTATGAA 1061
             +S A P S A          +GLP      DLG       +S G++ T   P  +T + 
Sbjct: 3995 EESTAFPGSPA-------STQTGLPATLTTADLGEESTTFPSSSGSTGTKLSPARSTTSG 4047

Query: 1062 DNGFLSHNFL-------TVAPGHSSHHSPGLQGQGVTLPGQPPLPEKKRASEGDRSLGSV 1114
              G  + + L       T  PG  S  +P L  +  T    P  P+   +     S G  
Sbjct: 4048 LVGESTPSRLSPSSTETTTLPG--SPTTPSLSEKSTTFYTSPRSPDATLSPATTTSSGVS 4105

Query: 1115 SPSSSGFSSPHSGSTISIPFPNVL--------PDFSKASEAASPLPDSPG 1156
              SS+  S P  GST +  FP+          P  S +S+ ++    SPG
Sbjct: 4106 EESSTSHSQP--GSTHTTAFPDSTTTSGLSQEPTTSHSSQGSTEATLSPG 4153



 Score = 42.4 bits (98), Expect = 0.003
 Identities = 195/867 (22%), Positives = 277/867 (31%), Gaps = 161/867 (18%)

Query: 378  NSPDHSDHTLSVSSDSGHSTASARTDKTEERLAPG-----------TRRGLSAQEKAELD 426
            +SPD S  T S    S HST S R + T  R++PG           T  GLS        
Sbjct: 2277 SSPDASGTTPS----SAHSTTSGRGESTTSRISPGSTEITTLPGSTTTPGLSEASTTFYS 2332

Query: 427  QLLSGFGLEDPGSSL-----KEMTDARSKYSGTRHVV-PAQVHVNGDAALKDRETDILDD 480
               S      P S       +E T +RS+   T   V PA     G   L +  T +   
Sbjct: 2333 SPRSPTTTLSPASMTSLGVGEESTTSRSQPGSTHSTVSPASTTTPG---LSEESTTVYSS 2389

Query: 481  EMPHHDLHSVDSLGTLS-SSEGPQSAHLGPFTCH-----KSSQNSLLSDGFGSNVGED-- 532
                 +        T S   E P + H  P + H     + S  S L++   +  G    
Sbjct: 2390 SPGSTETTVFPRTPTTSVRGEEPTTFHSRPASTHTTLFTEDSTTSGLTEESTAFPGSPAS 2449

Query: 533  -----PQGTLVPDLGLGMDGPYERERTFGSREPKQPQPLLRKPSVSAQMQAYGQSSYSTQ 587
                 P      DLG       E   TF S        L   P+ S      G+S+ S  
Sbjct: 2450 TQTGLPATLTTADLG-------EESTTFPSSSGSTGTTL--SPARSTTSGLVGESTPSR- 2499

Query: 588  TWVRQQQMVVAHQYSFAPDGEARLVSRCPADNPGLVQ------AQPRVP---LTPTRGTS 638
                            +P              P L +        PR P   L+P   TS
Sbjct: 2500 ---------------LSPSSTETTTLPGSPTTPSLSEKSTTFYTSPRSPDATLSPATTTS 2544

Query: 639  SRVAVQRGVGSGP--------HPPDTQQP-----------SPSKAFKPRFPGDQVVNGAG 679
            S V+ +                P  T  P           SP        P     +G  
Sbjct: 2545 SGVSEESSTSHSQPGSTHTTAFPDSTTTPGLSRHSTTSHSSPGSTDTTLLPASTTTSGPS 2604

Query: 680  PELSTG-PSPGSPTLDIDQSIEQLNRLILELDPTFEPIPTHMNALGSQANGSVSPDSV-- 736
             E +T   SPGS     D ++   +   L    +F    T  ++     + ++ PDS   
Sbjct: 2605 QESTTSHSSPGST----DTALSPGSTTAL----SFGQESTTFHSSPGSTHTTLFPDSTTS 2656

Query: 737  GGGLRASSRLPDTGEGPSRATGRQGSSAEQPLGGRLRKLSLGQYDNDAGGQLPFSKCAWG 796
             G + AS+R+  +  G  R T    SS    L G                  P +  A  
Sbjct: 2657 SGIVEASTRV-HSSTGSPRTTLSPASSTSPGLQGESTTFQTHPASTHTTPSPPSTATAPV 2715

Query: 797  KAGVDYAPNLPPFPSPADVKETMTPGYPQDLDII------DGRILSSKESMCSTPAFPVS 850
            +    Y  +    P+      + T G+ +   I        G   SS  S  S      +
Sbjct: 2716 EESTTYHRSPGSTPTTHFPASSTTSGHSEKSTIFHSSPDASGTTPSSAHSTTSGRGESTT 2775

Query: 851  PETPYVKTALRHPPFSPPEPPLSSPASQHKGGREPRSCPETLTHAVGMSESPIGPKSTML 910
                   T +   P S   P LS  ++       PRS   TL+ A  M+   +G +ST  
Sbjct: 2776 SRISPGSTEITTLPGSTTTPGLSEASTTFYSS--PRSPTTTLSPA-SMTSLGVGEESTTS 2832

Query: 911  RADASSTPSFQQAFASSCTISSNGPGQRRESSSSAERQWVESSPKPMVSLLGSGRPTGSP 970
            R+   ST S      +    S+  PG   ES++        SSP       GS   T  P
Sbjct: 2833 RSQPGSTHS------TVSPASTTTPGLSEESTTV-----YSSSP-------GSTETTVFP 2874

Query: 971  LSAEFSGTRKDSPVLSCFPPSELQAPFHSHELSLAEPPDSLAPPSSQAFLGFGTAPVGSG 1030
             S   S   ++       P S     F     +     +S A P S A          +G
Sbjct: 2875 RSTTTSVRGEEPTTFHSRPASTHTTLFTEDSTTSGLTEESTAFPGSPA-------STQTG 2927

Query: 1031 LPPE---EDLG---ALLANSHGASPTPSIPLTATGAADNGFLSHNFL-------TVAPGH 1077
            LP      DLG       +S G++ T   P  +T +   G  + + L       T  PG 
Sbjct: 2928 LPATLTTADLGEESTTFPSSSGSTGTTLSPARSTTSGLVGESTPSRLSPSSTETTTLPG- 2986

Query: 1078 SSHHSPGLQGQGVTLPGQPPLPEKKRASEGDRSLGSVSPSSSGFSSPHSGSTISIPFPNV 1137
             S  +P L  +  T    P  P+   +     S G    SS+  S P  GST +  FP+ 
Sbjct: 2987 -SPTTPSLSEKSTTFYTSPRSPDATLSPATTTSSGVSEESSTSHSQP--GSTHTTAFPDS 3043

Query: 1138 L--------PDFSKASEAASPLPDSPG 1156
                     P  S +S+ ++    SPG
Sbjct: 3044 TTTSGLSQEPTASHSSQGSTEATLSPG 3070



 Score = 40.0 bits (92), Expect = 0.016
 Identities = 118/528 (22%), Positives = 177/528 (33%), Gaps = 65/528 (12%)

Query: 656  TQQPSPSKAFKPRFPGDQVVNGAGPELSTGPSPGSPTLDIDQSIEQLNRLILELDPTFEP 715
            T   SP        P     +G   E +T  S    T   D ++   +   L    +F  
Sbjct: 1024 TSHSSPGSTDTTLLPASTTTSGPSQESTTSHSSSGST---DTALSPGSTTAL----SFGQ 1076

Query: 716  IPTHMNALGSQANGSVSPDSV--GGGLRASSRLPDTGEGPSRATGRQGSSAEQPLGGRLR 773
              T  ++     + ++ PDS    G + AS+R+  +  G  R T    SS    L G   
Sbjct: 1077 ESTTFHSNPGSTHTTLFPDSTTSSGIVEASTRV-HSSTGSPRTTLSPASSTSPGLQGEST 1135

Query: 774  KLSLGQYDNDAGGQLPFSKCAWGKAGVDYAPNLPPFPSPADVKETMTPGYPQDLDII--- 830
                           P +  A  +    Y  +    P+      + T G+ +   I    
Sbjct: 1136 AFQTHPASTHTTPSPPSTATAPVEESTTYHRSPGSTPTTHFPASSTTSGHSEKSTIFHSS 1195

Query: 831  ---DGRILSSKESMCSTPAFPVSPETPYVKTALRHPPFSPPEPPLSSPASQHKGGREPRS 887
                G   SS  S  S      +       T +   P S   P LS  ++       PRS
Sbjct: 1196 PDASGTTPSSAHSTTSGRGESTTSRISPGSTEITTLPGSTTTPGLSEASTTFYSS--PRS 1253

Query: 888  CPETLTHAVGMSESPIGPKSTMLRADASSTPSFQQAFASSCTISSNGPGQRRESSSSAER 947
               TL+ A  M+   +G +ST  R+   ST S      +    S+  PG   ES++    
Sbjct: 1254 PTTTLSPA-SMTSLGVGEESTTSRSQPGSTHS------TVSPASTTTPGLSEESTT---- 1302

Query: 948  QWVESSPKPMVSLLGSGRPTGSPLSAEFSGTRKDSPVLSCFPPSELQAPFHSHELSLAEP 1007
              V SS +      GS   T  P S   S   ++       P S     F     +    
Sbjct: 1303 --VYSSSR------GSTETTVFPHSTTTSVHGEEPTTFHSRPASTHTTLFTEDSTTSGLT 1354

Query: 1008 PDSLAPPSSQAFLGFGTAPVGSGLPPE---EDLG---ALLANSHGASPTPSIPLTATGAA 1061
             +S A P S A          +GLP      DLG       +S G++ T   P  +T + 
Sbjct: 1355 EESTAFPGSPA-------STQTGLPATLTTADLGEESTTFPSSSGSTGTKLSPARSTTSG 1407

Query: 1062 DNGFLSHNFL-------TVAPGHSSHHSPGLQGQGVTLPGQPPLPEKKRASEGDRSLGSV 1114
              G  + + L       T  PG  S  +P L  +  T    P  P+   +     S G  
Sbjct: 1408 LVGESTPSRLSPSSTETTTLPG--SPTTPSLSEKSTTFYTSPRSPDATLSPATTTSSGVS 1465

Query: 1115 SPSSSGFSSPHSGSTISIPFPNVLPDFSK------ASEAASPLPDSPG 1156
              SS+  S P S  T + P      D S+      +S+ ++    SPG
Sbjct: 1466 EESSTSHSQPGSTHTTAFPDSTTTSDLSQEPTTSHSSQGSTEATLSPG 1513



 Score = 38.5 bits (88), Expect = 0.047
 Identities = 78/364 (21%), Positives = 128/364 (35%), Gaps = 58/364 (15%)

Query: 844  TPAFPVSPETPYVK---TALRHPPFSPPEPPLSSPASQHKGGREPRSCPETLTHAVGMSE 900
            T A P S  TP +    T     P S P    S+ +S   G  E  +   +   A   + 
Sbjct: 4673 TTALPGSTTTPGLSEKSTTFHSSPSSTPTTHFSA-SSTTLGRSEESTTVHSSPVATATTP 4731

Query: 901  SPIGPKSTMLRADAS---STPSFQQAFASSCTISSNGPGQRRESSSSAERQWVESSPKPM 957
            SP    ++ L  +++   S+P   Q      + +++G  +   +S S+    + S P   
Sbjct: 4732 SPARSTTSGLVEESTAYHSSPGSTQTMHFPESSTASGRSEESRTSHSSTTHTISSPPSTT 4791

Query: 958  VSLL----------GSGRPTGSPLSAEFSGTRKDSPVLSCFPPSELQAPFHSHELSLAEP 1007
             +L+          GS   T  P S+  SG  ++S      P +    P  +H  +    
Sbjct: 4792 SALVEEPTSYHSSPGSIATTHFPESSTTSGRSEESTASHSSPDTNGITPLPAHFTTSGRI 4851

Query: 1008 PDS----LAPPSSQAFLGFGTAPVG----------SGLPPEEDLGALLANSHGASPTPS- 1052
             +S    ++P S +  L       G          S   P++ L      S   S  P+ 
Sbjct: 4852 AESTTFYISPGSMETTLASTATTPGLSAKSTILYSSSRSPDQTLSPASMTSSSISGEPTS 4911

Query: 1053 --------------IPLTATGAADNGFLSHNF-----LTVAPGHSSHHSPGLQGQGVTLP 1093
                             T +G +      H+       T++PG  +  S     Q  T P
Sbjct: 4912 LYSQAESTHTTAFPASTTTSGLSQESTTFHSKPGSTETTLSPGSITTSS---FAQEFTTP 4968

Query: 1094 GQPPLPEKKRASEGDRSLGSVSPSSSGF-SSPHSGSTISIPFPNVLPDFSKASEAASPLP 1152
               P       S    ++  +S  S+ F SSP S  T +    N +   S  S+ ++P P
Sbjct: 4969 HSQPGSALSTVSPASTTVPGLSEESTTFYSSPGSTETTAFSHSNTM---SIHSQQSTPFP 5025

Query: 1153 DSPG 1156
            DSPG
Sbjct: 5026 DSPG 5029



 Score = 38.1 bits (87), Expect = 0.062
 Identities = 65/304 (21%), Positives = 107/304 (35%), Gaps = 42/304 (13%)

Query: 873  SSPASQHKGGREPRSCPETLTHAVGMSESPIGPKSTMLRADASSTPSFQQAFASS----- 927
            +SP S   G  E  + P + T   G+SE     KST   +  SSTP+   + +S+     
Sbjct: 4663 TSPISS--GSMETTALPGSTT-TPGLSE-----KSTTFHSSPSSTPTTHFSASSTTLGRS 4714

Query: 928  -----------CTISSNGPGQRRESSSSAERQWVESSPKPMVSLLGSGRPTGSPLSAEFS 976
                        T ++  P +   S    E     SSP       GS +    P S+  S
Sbjct: 4715 EESTTVHSSPVATATTPSPARSTTSGLVEESTAYHSSP-------GSTQTMHFPESSTAS 4767

Query: 977  GTRKDSPVLSCFPPSELQAPFHSHELSLAEPPDSLAPPSSQAFLGFGTAPVGSGLPPEED 1036
            G  ++S          + +P  +    + EP    + P S A   F  +   SG   E  
Sbjct: 4768 GRSEESRTSHSSTTHTISSPPSTTSALVEEPTSYHSSPGSIATTHFPESSTTSGRSEEST 4827

Query: 1037 LGALLANSHGASPTPSIPLTATGAADNGFLSHNFLTVAPGH------SSHHSPGLQGQGV 1090
                  +++G +P P+   T+   A++         ++PG       S+  +PGL  +  
Sbjct: 4828 ASHSSPDTNGITPLPAHFTTSGRIAES-----TTFYISPGSMETTLASTATTPGLSAKST 4882

Query: 1091 TLPGQPPLPEKKRASEGDRSLGSVSPSSSGFSSPHSGSTISIPFPNVLPDFSKASEAASP 1150
             L      P++  +     S       +S +S   S  T + P        S+ S     
Sbjct: 4883 ILYSSSRSPDQTLSPASMTSSSISGEPTSLYSQAESTHTTAFPASTTTSGLSQESTTFHS 4942

Query: 1151 LPDS 1154
             P S
Sbjct: 4943 KPGS 4946



 Score = 37.7 bits (86), Expect = 0.081
 Identities = 171/842 (20%), Positives = 275/842 (32%), Gaps = 98/842 (11%)

Query: 344  HTQGPVDGSLYAKVRKKSSSDPGIPGGPQA-IPAT-NSPDHSDHTLSVSSDSGHS----- 396
            HT    + S  + + ++S++ PG P   Q  +PAT  + D  + + +  S SG +     
Sbjct: 3980 HTTLFTEDSTTSGLTEESTAFPGSPASTQTGLPATLTTADLGEESTTFPSSSGSTGTKLS 4039

Query: 397  -----TASARTDKTEERLAPGTRRGLS---AQEKAELDQLLSGF--GLEDPGSSLKEMTD 446
                 T+    + T  RL+P +    +   +     L +  + F      P ++L   T 
Sbjct: 4040 PARSTTSGLVGESTPSRLSPSSTETTTLPGSPTTPSLSEKSTTFYTSPRSPDATLSPATT 4099

Query: 447  ARS---KYSGTRHVVPAQVHVNGDAALKDRETDILDDEMPHHDLHSVDSLGTLSSSEGPQ 503
              S   + S T H  P   H     A  D  T     + P           T  SS+G  
Sbjct: 4100 TSSGVSEESSTSHSQPGSTHTT---AFPDSTTTSGLSQEPT----------TSHSSQGST 4146

Query: 504  SAHLGPFTCHKSSQNSLLSDGFGSNVGEDPQGTLVPDLGLGMDGPYERERTFGSREPKQP 563
             A L P +   SS     S  F S+ G D + TL+PD  +   G  E      S      
Sbjct: 4147 EATLSPGSTTASSLGQQ-STTFHSSPG-DTETTLLPDDTI-TSGLVEASTPTHSSTGSLH 4203

Query: 564  QPLLRKPSVSAQMQAYGQSSYSTQTWVRQQQMVVAHQYSFAPDGEARLVSRCPADNPGLV 623
              L    S S  +Q   + S + Q+W        +   + A   E   VS      P   
Sbjct: 4204 TTLTPASSTSTGLQ---EESTTFQSWPSSSDTTPSPPSTTAVPVE---VSTTYHSRPS-- 4255

Query: 624  QAQPRVPLTPTRGTSSRVAVQRGVGSGPHPPDTQQPSPSKAFKPRFPGDQVVN--GAGPE 681
             + P    + +  T  R      V S P    T    P+++      G+   +   +G  
Sbjct: 4256 -STPTTHFSASSTTLGRSEESTTVHSSPGATGTAL-FPTRSATSVLVGEPTTSPISSGST 4313

Query: 682  LSTGPSPGSPTLDIDQSIEQLNRLILELDPTFEPIPTHMNALGSQANGSVS-PDSVGG-G 739
             +T     + T  + +            D T  P  T  + +  ++  S S P S+    
Sbjct: 4314 ETTALPGSTTTAGLSEKSTTFYSSPRSPDTTLSPASTTSSGVSEESTTSHSRPGSMHTTA 4373

Query: 740  LRASSRLPDTGEGPSRATGRQGSSAEQPLGGRLRKLSLGQYDNDAGGQLPFSKCAWGKAG 799
              +S+ +P   +  + +    GS+      G     SLG          P S       G
Sbjct: 4374 FPSSTTMPGVSQESTASHSSPGSTDTTLSPGSTTASSLG----------PESTTFHSSPG 4423

Query: 800  VDYAPNLPPFPSPADVKETMTP-----GYPQDLDIIDGRILSSKESMCSTPAFPVSPETP 854
                  LP   + + + E  TP     G P       G      ES  +  ++P S +T 
Sbjct: 4424 STETTLLPDNTTASGLLEASTPVHSSTGSPHTTLSPAGSTTRQGEST-TFQSWPNSKDTT 4482

Query: 855  YVKTALRHPPFSPPEPPLSSPASQHKGGREPRSCPETLTHAVGMSESPIGPKSTMLRADA 914
                         P PP ++ A          S   T T     S + +G      R++ 
Sbjct: 4483 -------------PAPPTTTSAFVELSTTSHGSPSSTPTTHFSASSTTLG------RSEE 4523

Query: 915  SSTPSFQQAFASSCTISSNGPGQRRESSSSAERQWVESSPKPMVSLLGSGRPTGSPLSAE 974
            S+T           T ++  P +   S    E     SSP       GS +    P S  
Sbjct: 4524 STTVHSSPV----ATATTPSPARSTTSGLVEESTTYHSSP-------GSTQTMHFPESNT 4572

Query: 975  FSGTRKDSPVLSCFPPSELQAPFHSHELSLAEPPDSLAPPSSQAFLGFGTAPVGSGLPPE 1034
             SG  ++S          + +   +    + EP    + P S A   F  +   SG   E
Sbjct: 4573 TSGRGEESTTSHSSTTHTISSAPSTTSALVEEPTSYHSSPGSTATTHFPDSSTTSGRSEE 4632

Query: 1035 EDLGALLANSHGASPTPSIPLTAT--GAADNGFLSHNFLTVAPGHSSHHSPGLQGQGVTL 1092
                    ++ G    P+   T+   G +    +S   +       S  +PGL  +  T 
Sbjct: 4633 STASHSSQDATGTIVLPARSTTSVLLGESTTSPISSGSMETTALPGSTTTPGLSEKSTTF 4692

Query: 1093 PGQPPLPEKKRASEGDRSLGSVSPSSSGFSSPHSGSTISIPFPNVLPDFSKASEAASPLP 1152
               P        S    +LG    S++  SSP + +T   P  +      + S A    P
Sbjct: 4693 HSSPSSTPTTHFSASSTTLGRSEESTTVHSSPVATATTPSPARSTTSGLVEESTAYHSSP 4752

Query: 1153 DS 1154
             S
Sbjct: 4753 GS 4754



 Score = 35.0 bits (79), Expect = 0.52
 Identities = 71/293 (24%), Positives = 104/293 (35%), Gaps = 62/293 (21%)

Query: 873  SSPASQHKGGREPRSCPETLTHAVGMSESPIGPKSTMLRADASSTPSFQQAFASSCTISS 932
            SSP S  +     R+    ++     S S  GP  T+   D+++ P   Q   +S +I  
Sbjct: 285  SSPRSPDRTLSPARTTSSGVSEKSTTSHSRPGPTHTIAFPDSTTMPGVSQESTASHSIPG 344

Query: 933  N-----GPGQRRESSSSAERQWVESSPKPMVSLLGSGRPTGSPLSAEFSGTRKDSPVLSC 987
            +      PG    SS   E     SSP       G  + T  P +   SG          
Sbjct: 345  STDTTLSPGTTTPSSLGPESTTFHSSP-------GYTKTTRLPDNTTTSGL--------- 388

Query: 988  FPPSELQAPFHSHELSLAEPPDSLAPPSSQAFLG-----------FGTAPVGSGLPPEED 1036
                E   P HS   S   P  +L+P SS    G             T+P  SG      
Sbjct: 389  ---LEASTPVHS---STGSPHTTLSPSSSTTHEGEPTTFQSWPSSKDTSPAPSG---TTS 439

Query: 1037 LGALLANSHGASPTPSIPLTATGAADNGFLSHNFLTVAPGHSSHHSPGLQGQGVTLPGQP 1096
                L+ ++ +SP+ S P T   A+          +   GHS   +P +    V     P
Sbjct: 440  AFVKLSTTYHSSPS-STPTTHFSAS----------STTLGHSEESTP-VHSSPVATATTP 487

Query: 1097 PLPEKKRASEGDRSLGSVSPSSSGFSSPHSGSTISIPFPNVLPDFSKASEAAS 1149
            P P +   S      G V  S++   SP  GST ++ FP        + E+A+
Sbjct: 488  P-PARSATS------GHVEESTAYHRSP--GSTQTMHFPESSTTSGHSEESAT 531


>gi|188536004 zinc finger protein 469 [Homo sapiens]
          Length = 3925

 Score = 50.4 bits (119), Expect = 1e-05
 Identities = 79/295 (26%), Positives = 103/295 (34%), Gaps = 46/295 (15%)

Query: 611 LVSRCPADNPGLVQAQPRVPLTPTRGTSSRVAVQRGVGSGPHPPDTQ--QPSPSKAFKPR 668
           L  R P+   GL   +      P R    +     GV + P PPDT+   P P  A  P+
Sbjct: 380 LPERPPSAQDGLGSTRGPPSSLPQRHFPGQAYRASGVDTSPGPPDTELAAPGPPPARLPQ 439

Query: 669 F-----------PGDQVVNGAGPELSTGPSPGSPTLDIDQSIEQLNRLILELDPTFEPIP 717
                       PG  +        +  PSPG   L + QS       +L   PT  P P
Sbjct: 440 LWDPTAAPYPTPPGGPLAATRSMFFNGQPSPGQ-RLCLPQSAPLPWPQVL---PTARPSP 495

Query: 718 THMNALGSQANGSVSPDSVG---GGLRASSRLPDTGEG-PSRATGRQGSSAEQPLGGRLR 773
             M  L      +  P+  G   G L  + + P   E  P+  + + GS A     G   
Sbjct: 496 HGMEMLSRLPFPAGGPEWQGGSQGALGTAGKTPGPREKLPAVRSSQGGSPALFTYNGM-- 553

Query: 774 KLSLGQYDNDAGGQLPFSKCAWGKAGVDYAPNLPPFPSPADVKETMTPGYPQDLDIIDGR 833
                    D G Q  F   A  +      P+LPP P       + +P  P       G 
Sbjct: 554 --------TDPGAQPLFFGVAQPQVSPHGTPSLPP-PRVVGASPSESP-LPSPATNTAGS 603

Query: 834 ILSSKESMCSTPAFPVSPET----PYVKTALRHP---------PFSPPEPPLSSP 875
             SS   M S+PA P S E+    P   +A  HP         PF  PEPP S P
Sbjct: 604 TCSSLSPMSSSPANPSSEESQLPGPLGPSAFFHPPTHPQETGSPFPSPEPPHSLP 658


>gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens]
          Length = 2752

 Score = 49.7 bits (117), Expect = 2e-05
 Identities = 85/387 (21%), Positives = 141/387 (36%), Gaps = 39/387 (10%)

Query: 782  NDAGGQLPFSKCAWGKAGVDYAPNLPPFPSPADVKETMTPGYPQDLDIIDGRILSSKE-- 839
            N AG + P +  A    G    P    +PS      + TP  P   +++  R   +    
Sbjct: 2296 NLAGARTPAALAALSLTGSGTPPTAANYPS-----SSRTPQAPASANLVGPRSAHATAPV 2350

Query: 840  ----SMCSTPAFPVSPETPYVKTALRHPPFSPPEPPLSSPASQHKGGREPRSCPETLTHA 895
                S  +    P S  +  +  AL     + P  PLS  A +   GR   + P  L  A
Sbjct: 2351 NIAGSRTAAALAPASLTSARMAPALSGANLTSPRVPLS--AYERVSGR---TSPPLLDRA 2405

Query: 896  VGMSESPIGPKSTMLRADASSTPSFQQAFASSCTISSNGPGQRRESSSSAERQWVESSPK 955
               +  P  P  + + ++ + +PS +   A S ++      Q R    SA          
Sbjct: 2406 RSRTP-PSAPSQSRMTSERAPSPSSRMGQAPSQSLLPPAQDQPRSPVPSAFSDQSRCLIA 2464

Query: 956  PMVSLLGSGRPTGSPLSAEFSGTRKDSPVLSCFPPSELQAPFHSHELSLAEPPDSLAPPS 1015
                + GS   +   ++   S     + +LS      + AP   H   + EPP S     
Sbjct: 2465 QTTPVAGSQSLSSGAVATTTSSAGDHNGMLS------VPAPGVPHS-DVGEPPASTGAQQ 2517

Query: 1016 SQAFLGFGTAPVGSGLPPEEDLGALLANSHGASPTPSIPLTATGAADNGFLSHNF----L 1071
              A          + L P ++  +  ++S  +S + S   +++ ++ +G  S +     L
Sbjct: 2518 PSAL---------AALQPAKERRSSSSSSSSSSSSSSSSSSSSSSSSSGSSSSDSEGSSL 2568

Query: 1072 TVAPGHSSHH--SPGLQGQGVTLPGQPPLPEKKRASEGDRSLGSVSPSSSGFSSPHSGST 1129
             V P  +     SP    +     G+PP P   +      S  S S SSS  SS  S S+
Sbjct: 2569 PVQPEVALKRVPSPTPAPKEAVREGRPPEPTPAKRKRRSSSSSSSSSSSSSSSSSSSSSS 2628

Query: 1130 ISIPFPNVLPDFSKASEAASPLPDSPG 1156
             S    +     S +S ++SP P  PG
Sbjct: 2629 SSSSSSSSSSSSSSSSSSSSPSPAKPG 2655



 Score = 38.5 bits (88), Expect = 0.047
 Identities = 50/206 (24%), Positives = 70/206 (33%), Gaps = 27/206 (13%)

Query: 755 RATGRQGSSAEQPLGGRLRKLSLGQYDNDAGGQLPFSKCAWGKAGVDYAPNLPPF----- 809
           R+T    +S+      R R  +   +     G+ P    A G+ G   AP   P      
Sbjct: 262 RSTSADSASSSDTSRSRSRSAAAKTHTTALAGRSPSP--ASGRRGEGDAPFSEPGTTSTQ 319

Query: 810 -PSPADVKETMTPGYPQDLDIIDGRILSSKESMCSTPAFPVSPETPYVKTALRHPPFSPP 868
            PS  +   T  P  P +    D +  S+     S       PE P     L       P
Sbjct: 320 RPSSPETA-TKQPSSPYEDKDKDKKEKSATRPSPSPERSSTGPEPPAPTPLLAERHGGSP 378

Query: 869 EPPLSSPASQHKGG----------REPRSCPETLTHAVGMSESPIGPKSTMLRADASSTP 918
           +P  ++P SQ              R P   PE L  +     SP  P+ T +   ASS+P
Sbjct: 379 QPLATTPLSQEPVNPPSEASPTRDRSPPKSPEKLPQSSSSESSPPSPQPTKVSRHASSSP 438

Query: 919 SFQQAFASSCTISSNGPGQRRESSSS 944
              +         +  PG  RE SSS
Sbjct: 439 ESPK--------PAPAPGSHREISSS 456



 Score = 33.9 bits (76), Expect = 1.2
 Identities = 36/123 (29%), Positives = 56/123 (45%), Gaps = 15/123 (12%)

Query: 836  SSKESMCSTPAFPVSPETPYVKTALRHPPFSPPEPPLSSPASQHKGGREPRSCPETLTHA 895
            SS  S  S+ +   SP  P  +   +  P SP +PP     S     R PR   ++L  +
Sbjct: 2636 SSSSSSSSSSSSSPSPAKPGPQALPK--PASPKKPPPGERRS-----RSPRKPIDSLRDS 2688

Query: 896  VGMSESPIGPKSTMLRADASSTPSFQQAFASSCTISSNGPGQRRESSSSAERQWVES-SP 954
              +S SP+  +    R     +P  QQ   SS +   +  GQR +S S + ++  E+ SP
Sbjct: 2689 RSLSYSPVERR----RPSPQPSPRDQQ---SSSSERGSRRGQRGDSRSPSHKRRRETPSP 2741

Query: 955  KPM 957
            +PM
Sbjct: 2742 RPM 2744



 Score = 31.2 bits (69), Expect = 7.6
 Identities = 75/353 (21%), Positives = 120/353 (33%), Gaps = 43/353 (12%)

Query: 322  NTTDPLIRWDSYENLSADGEVLHTQGPVDGSLYAKVRKKSSSDPGIPGGPQAIPATNSPD 381
            N T P +   +YE +S       T  P+        R +S + P  P        + S  
Sbjct: 2379 NLTSPRVPLSAYERVSG-----RTSPPLLD------RARSRTPPSAP--------SQSRM 2419

Query: 382  HSDHTLSVSSDSGHSTASARTDKTEERLAPGTRRGLSAQEKAELDQLLSGFGLEDPGSSL 441
             S+   S SS  G + + +     +++         S Q +  + Q     G +   S  
Sbjct: 2420 TSERAPSPSSRMGQAPSQSLLPPAQDQPRSPVPSAFSDQSRCLIAQTTPVAGSQSLSSGA 2479

Query: 442  KEMTDARSKYSGTRHVVPAQVHVNGD-----AALKDRETDILDDEMPHHDLHSVDSLGTL 496
               T + +        VPA    + D     A+   ++   L    P  +  S  S  + 
Sbjct: 2480 VATTTSSAGDHNGMLSVPAPGVPHSDVGEPPASTGAQQPSALAALQPAKERRSSSSSSSS 2539

Query: 497  SSSEGPQSAHLGPFTCHKSSQNSLLSDGFGSNVGEDPQGTL--VPDLGLGMDGPYERERT 554
            SSS    S+     +   SS  S  SD  GS++   P+  L  VP        P  +E  
Sbjct: 2540 SSSSSSSSSS----SSSSSSSGSSSSDSEGSSLPVQPEVALKRVPS-----PTPAPKEAV 2590

Query: 555  FGSREPKQPQPLLRKPSVSAQMQAYGQSSYSTQTWVRQQQMVVAHQYSFAPDGEARLVSR 614
               R P +P P  RK   S+   +   SS S+ +         +   S +    +   S 
Sbjct: 2591 REGR-PPEPTPAKRKRRSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSP 2649

Query: 615  CPADNPGLVQAQPRVPLTPTRGTSSRVAVQRGVGSGPHPPDTQQPSPSKAFKP 667
             PA        +P  P  P  G       +R   S   P D+ + S S ++ P
Sbjct: 2650 SPAKPGPQALPKPASPKKPPPG-------ERRSRSPRKPIDSLRDSRSLSYSP 2695


>gi|239508976 PREDICTED: mucin 12, cell surface associated [Homo
            sapiens]
          Length = 2036

 Score = 48.9 bits (115), Expect = 4e-05
 Identities = 119/543 (21%), Positives = 177/543 (32%), Gaps = 69/543 (12%)

Query: 630  PLTPTRGTSSRVAVQ----RGVGSG-PHPPDTQQPSPSKAFKPRFPGDQVVNGAGPELST 684
            P T + G+ S +       R   SG      T   SP       FP     +G G E +T
Sbjct: 287  PSTTSHGSPSSIPTTHISARSTTSGLVEESTTYHSSPGSTQTMHFPESDTTSGRGEESTT 346

Query: 685  GPSPGSPTLDIDQSIEQLNRLILELDPTFEPIPTHMNALGSQANGSVSPDSVGGGLRASS 744
              S  + T+    S       ++E     EP   H +                 G  A++
Sbjct: 347  SHSSTTHTI---SSAPSTTSALVE-----EPTSYHSSP----------------GSTATT 382

Query: 745  RLPDTGEGPSRATGRQGSSAEQPLGGRLRKLSLGQYDNDAGGQLPFSKCAWGKAGVDYAP 804
              PD+     R+     S + Q   G +  L      +   G+   S  + G       P
Sbjct: 383  HFPDSSTTSGRSEESTASHSSQDATGTI-VLPARSTTSVLLGESTTSPISSGSMETTALP 441

Query: 805  NLPPFP-----------SPADVKETMTPGYPQDLDIIDGRILS-SKESMCSTPAFPVSPE 852
                 P           SP     T++P       + +    S S+     T AFP S  
Sbjct: 442  GSTTTPGLSERSTTFHSSPRSPATTLSPASTTSSGVSEESTTSRSRPGSTHTTAFPDSTT 501

Query: 853  TPYVKTALRHPPFSPPEPPLSS----PASQHKGGREPRSCPETLTHAVGMSESPIGPKST 908
            TP +    RH   S   P  +     PAS    G    S           S S  G   T
Sbjct: 502  TPGLS---RHSTTSHSSPGSTDTTLLPASTTTSGPSQEST---------TSHSSSGSTDT 549

Query: 909  MLRADASSTPSFQQAFASSCTISSNGPGQRRES---SSSAERQWVESSPKPMVSLLGSGR 965
             L   +++  SF Q    S T  SN PG    +    S+     VE+S + + S  GS R
Sbjct: 550  ALSPGSTTALSFGQ---ESTTFHSN-PGSTHTTLFPDSTTSSGIVEASTR-VHSSTGSPR 604

Query: 966  PTGSPLSAEFSGTRKDSPVLSCFPPS--ELQAPFHSHELSLAEPPDSLAPPSSQAFLGFG 1023
             T SP S+   G + +S      P S     +P  +    + E       P S     F 
Sbjct: 605  TTLSPASSTSPGLQGESTAFQTHPASTHTTPSPPSTATAPVEESTTYHRSPGSTPTTHFP 664

Query: 1024 TAPVGSGLPPEEDLGALLANSHGASPTPSIPLTA-TGAADNGFLSHNFLTVAPGHSSHHS 1082
             +   SG   +  +     ++ G +P+ +   T+  G +    +S     +     S  +
Sbjct: 665  ASSTTSGHSEKSTIFHSSPDASGTTPSSAHSTTSGRGESTTSRISPGSTEITTLPGSTTT 724

Query: 1083 PGLQGQGVTLPGQPPLPEKKRASEGDRSLGSVSPSSSGFSSPHSGSTISIPFPNVLPDFS 1142
            PGL     T    P  P    +     SLG    S++  S P S  +   P     P  S
Sbjct: 725  PGLSEASTTFYSSPRSPTTTLSPASMTSLGVGEESTTSRSQPGSTHSTVSPASTTTPGLS 784

Query: 1143 KAS 1145
            + S
Sbjct: 785  EES 787



 Score = 45.1 bits (105), Expect = 5e-04
 Identities = 196/880 (22%), Positives = 282/880 (32%), Gaps = 170/880 (19%)

Query: 378  NSPDHSDHTLSVSSDSGHSTASARTDKTEERLAPGTRRGLSAQEKAELDQLLSGFGLEDP 437
            +SPD S  T S    S HST S R + T  R++PG+          E+  L        P
Sbjct: 681  SSPDASGTTPS----SAHSTTSGRGESTTSRISPGS---------TEITTLPGS--TTTP 725

Query: 438  GSSLKEMTDARSKYSGTRHVVPAQVHVNGDAALKDRETDILDDEMPHHDLHSVDSLGTLS 497
            G S    T   S  S T  + PA +      +L   E        P     +V    T +
Sbjct: 726  GLSEASTTFYSSPRSPTTTLSPASM-----TSLGVGEESTTSRSQPGSTHSTVSPASTTT 780

Query: 498  SSEGPQSAHLGPFTCHKSSQNSLLSDGFGSNVGEDPQGTLVPDLGLGMDGPYERERTFGS 557
                 +S      T + SS+ S  +  F  +      G              E   TF S
Sbjct: 781  PGLSEEST-----TVYSSSRGSTETTVFPHSTTTSVHG--------------EEPTTFHS 821

Query: 558  REPKQPQPLLRKPSVSA----QMQAYGQSSYSTQTWVRQQQMVV-----AHQYSFAPDGE 608
            R       L  + S ++    +  A+  S  STQT +            +  +  +    
Sbjct: 822  RPASTHTTLFTEDSTTSGLTEESTAFPGSPASTQTGLPATLTTADLGEESTTFPSSSGST 881

Query: 609  ARLVSRCPADNPGLVQAQPRVPLTPTRGTSSRVAVQRGVGSGPHPPDTQQPSPSKAFKPR 668
               +S   +   GLV        TP+R + S        GS P  P   + S +    PR
Sbjct: 882  GTKLSPARSTTSGLVGES-----TPSRLSPSSTETTTLPGS-PTTPSLSEKSTTFYTSPR 935

Query: 669  FP------GDQVVNGAGPELSTGPS-PGSP----------TLDIDQSIEQLNRLILELDP 711
             P           +G   E ST  S PGS           T D+ Q     +      + 
Sbjct: 936  SPDATLSPATTTSSGVSEESSTSHSQPGSTHTTAFPDSTTTSDLSQEPTTSHSSQGSTEA 995

Query: 712  TFEPIPTHMNALGSQANGSVSP-----------DSVGGGLRASSRLPDTGEGPSRATGRQ 760
            T  P  T  ++LG Q+    S            D++  GL  +S    +  G    T   
Sbjct: 996  TLSPGSTTASSLGQQSTTFHSSPGDTETTLLPDDTITSGLVEASTPTHSSTGSLHTTLTP 1055

Query: 761  GSSAEQPLGGRLRKLSLGQYDNDAGGQLPFSKCAWGKAGVDYAPNLPPFPSPADVKETMT 820
             SS    L             +D     P +  A  +    Y       P+      + T
Sbjct: 1056 ASSTSAGLQEESTTFQSWPSSSDTTPSPPGTTAAPVEVSTTYHSRPSSTPTTHFSASSTT 1115

Query: 821  PGYPQDLDIIDGRILSSKESMCSTPAFPVSPETPYVKTALRHPPFSPPEPPLSSPASQHK 880
             G  ++   +      S      T  FP    T  +          P   P+SS      
Sbjct: 1116 LGRSEESTTVH-----SSPGATGTALFPTRSATSVLVG-------EPTTSPISS------ 1157

Query: 881  GGREPRSCPETLTHAVGMSE-------SPIGPKSTMLRADASSTPSFQQAFAS----SCT 929
            G  E  + P + T A G+SE       SP  P +T+  A  +S+   +++  S      T
Sbjct: 1158 GSTETTALPGSTTTA-GLSEKSTTFYSSPRSPDTTLSPASTTSSGVSEESTTSHSRPGST 1216

Query: 930  ISSNGPGQRRESSSSAERQWVESSPKPMVSLLGSGRPTGSPLSAEFSGTRKDSP---VLS 986
             ++  PG       S E     SSP    + L  G  T S L  E S T   SP     +
Sbjct: 1217 HTTAFPGSTTMPGVSQESTASHSSPGSTDTTLSPGSTTASSLGPE-STTFHSSPGSTETT 1275

Query: 987  CFPPS-------ELQAPFHSHELSLAEPPDSLAPPSSQAFLGFGTA----PVGSGLPPEE 1035
              P +       E   P HS   S   P  +L+P  S    G  T     P      P  
Sbjct: 1276 LLPDNTTASGLLEASTPVHS---STGSPHTTLSPAGSTTRQGESTTFQSWPSSKDTMPAP 1332

Query: 1036 DLGA-----LLANSHGA-SPTPSIPLTAT----GAADNGFLSHNF-----LTVAPGHSS- 1079
                     L   SHG+ S TP+   +A+    G ++     H+       T +P  S+ 
Sbjct: 1333 PTTTSAFVELSTTSHGSPSSTPTTHFSASSTTLGRSEESTTVHSSPVATATTPSPARSTT 1392

Query: 1080 ----------HHSPGLQGQGVTLPGQPPLP---EKKRASEGDRSLGSVSPSS-------- 1118
                      H SPG   Q +  P         E+ R S    +    SP S        
Sbjct: 1393 SGLVEESTAYHSSPG-STQTMHFPESSTASGRSEESRTSHSSTTHTISSPPSTTSALVEE 1451

Query: 1119 --SGFSSPHSGSTISIPFPNVLPDFSKASEAASPLPDSPG 1156
              S  SSP S +T   P  +     S+ S A+   PD+ G
Sbjct: 1452 PTSYHSSPGSIATTHFPESSTTSGRSEESTASHSSPDTNG 1491



 Score = 44.3 bits (103), Expect = 9e-04
 Identities = 90/338 (26%), Positives = 125/338 (36%), Gaps = 62/338 (18%)

Query: 843  STPAFPVSPETP-------YVKTALRHPPFSPPEPPLSSPASQHKGGREPRSCPETLTHA 895
            STP+  V   TP          TAL   P S  +P LS  ++       PRS P+T    
Sbjct: 86   STPSVLVGDSTPSPISSGSMETTAL---PGSTTKPGLSEKSTTFYSS--PRS-PDTTHLP 139

Query: 896  VGMSESPIGPKSTMLRADASSTPSFQQAFASSCTISSNGPGQRRESSSSAERQWVESSPK 955
              M+ S +  +ST   +   ST +   AF  S T+    PG  +ES++S       SSP 
Sbjct: 140  ASMTSSGVSEESTTSHSRPGSTHT--TAFPGSTTM----PGLSQESTAS------HSSPG 187

Query: 956  PMVSLLGSGRPTGSPLSAEFS--GTRKDSPVLSCFPPS-------ELQAPFHSHELSLAE 1006
            P  + L  G  T S L  E++   +R  S   +  P +       E   P HS   S   
Sbjct: 188  PTDTTLSPGSTTASSLGPEYTTFHSRPGSTETTLLPDNTTASGLLEASMPVHS---STRS 244

Query: 1007 PPDSLAPPSSQAFLGFGTAPVGSGLPPEEDLGALLANSHGASPTPSIPLTATGAADNGFL 1066
            P  +L+P  S    G  T       P  +D              P+ P T +   +    
Sbjct: 245  PHTTLSPAGSTTRQGEST--TFHSWPSSKD------------TRPAPPTTTSAFVEPSTT 290

Query: 1067 SHNFLTVAP-GHSSHHS--PGLQGQGVTLPGQP------PLPEKKRAS-EGDRSLGSVSP 1116
            SH   +  P  H S  S   GL  +  T    P        PE    S  G+ S  S S 
Sbjct: 291  SHGSPSSIPTTHISARSTTSGLVEESTTYHSSPGSTQTMHFPESDTTSGRGEESTTSHSS 350

Query: 1117 SSSGFSSPHSGSTISIPFPNVLPDFSKASEAASPLPDS 1154
            ++   SS  S ++  +  P      S  S A +  PDS
Sbjct: 351  TTHTISSAPSTTSALVEEPTSYHS-SPGSTATTHFPDS 387



 Score = 40.0 bits (92), Expect = 0.016
 Identities = 118/528 (22%), Positives = 177/528 (33%), Gaps = 65/528 (12%)

Query: 656  TQQPSPSKAFKPRFPGDQVVNGAGPELSTGPSPGSPTLDIDQSIEQLNRLILELDPTFEP 715
            T   SP        P     +G   E +T  S    T   D ++   +   L    +F  
Sbjct: 511  TSHSSPGSTDTTLLPASTTTSGPSQESTTSHSSSGST---DTALSPGSTTAL----SFGQ 563

Query: 716  IPTHMNALGSQANGSVSPDSV--GGGLRASSRLPDTGEGPSRATGRQGSSAEQPLGGRLR 773
              T  ++     + ++ PDS    G + AS+R+  +  G  R T    SS    L G   
Sbjct: 564  ESTTFHSNPGSTHTTLFPDSTTSSGIVEASTRV-HSSTGSPRTTLSPASSTSPGLQGEST 622

Query: 774  KLSLGQYDNDAGGQLPFSKCAWGKAGVDYAPNLPPFPSPADVKETMTPGYPQDLDII--- 830
                           P +  A  +    Y  +    P+      + T G+ +   I    
Sbjct: 623  AFQTHPASTHTTPSPPSTATAPVEESTTYHRSPGSTPTTHFPASSTTSGHSEKSTIFHSS 682

Query: 831  ---DGRILSSKESMCSTPAFPVSPETPYVKTALRHPPFSPPEPPLSSPASQHKGGREPRS 887
                G   SS  S  S      +       T +   P S   P LS  ++       PRS
Sbjct: 683  PDASGTTPSSAHSTTSGRGESTTSRISPGSTEITTLPGSTTTPGLSEASTTFYSS--PRS 740

Query: 888  CPETLTHAVGMSESPIGPKSTMLRADASSTPSFQQAFASSCTISSNGPGQRRESSSSAER 947
               TL+ A  M+   +G +ST  R+   ST S      +    S+  PG   ES++    
Sbjct: 741  PTTTLSPA-SMTSLGVGEESTTSRSQPGSTHS------TVSPASTTTPGLSEESTT---- 789

Query: 948  QWVESSPKPMVSLLGSGRPTGSPLSAEFSGTRKDSPVLSCFPPSELQAPFHSHELSLAEP 1007
              V SS +      GS   T  P S   S   ++       P S     F     +    
Sbjct: 790  --VYSSSR------GSTETTVFPHSTTTSVHGEEPTTFHSRPASTHTTLFTEDSTTSGLT 841

Query: 1008 PDSLAPPSSQAFLGFGTAPVGSGLPPE---EDLG---ALLANSHGASPTPSIPLTATGAA 1061
             +S A P S A          +GLP      DLG       +S G++ T   P  +T + 
Sbjct: 842  EESTAFPGSPA-------STQTGLPATLTTADLGEESTTFPSSSGSTGTKLSPARSTTSG 894

Query: 1062 DNGFLSHNFL-------TVAPGHSSHHSPGLQGQGVTLPGQPPLPEKKRASEGDRSLGSV 1114
              G  + + L       T  PG  S  +P L  +  T    P  P+   +     S G  
Sbjct: 895  LVGESTPSRLSPSSTETTTLPG--SPTTPSLSEKSTTFYTSPRSPDATLSPATTTSSGVS 952

Query: 1115 SPSSSGFSSPHSGSTISIPFPNVLPDFSK------ASEAASPLPDSPG 1156
              SS+  S P S  T + P      D S+      +S+ ++    SPG
Sbjct: 953  EESSTSHSQPGSTHTTAFPDSTTTSDLSQEPTTSHSSQGSTEATLSPG 1000



 Score = 39.7 bits (91), Expect = 0.021
 Identities = 184/854 (21%), Positives = 283/854 (33%), Gaps = 159/854 (18%)

Query: 344  HTQGPVDGSLYAKVRKKSSSDPGIPGGPQA-IPAT-NSPDHSDHTLSVSSDSGHS----- 396
            HT    + S  + + ++S++ PG P   Q  +PAT  + D  + + +  S SG +     
Sbjct: 827  HTTLFTEDSTTSGLTEESTAFPGSPASTQTGLPATLTTADLGEESTTFPSSSGSTGTKLS 886

Query: 397  -----TASARTDKTEERLAPGTRRGLS---AQEKAELDQLLSGF--GLEDPGSSLKEMTD 446
                 T+    + T  RL+P +    +   +     L +  + F      P ++L   T 
Sbjct: 887  PARSTTSGLVGESTPSRLSPSSTETTTLPGSPTTPSLSEKSTTFYTSPRSPDATLSPATT 946

Query: 447  ARS---KYSGTRHVVPAQVHVNGDAALKDRETDILDDEMPHHDLHSVDSLGTLSSSEGPQ 503
              S   + S T H  P   H           T    D     DL    +  T  SS+G  
Sbjct: 947  TSSGVSEESSTSHSQPGSTH-----------TTAFPDSTTTSDLSQEPT--TSHSSQGST 993

Query: 504  SAHLGPFTCHKSSQNSLLSDGFGSNVGEDPQGTLVPDLGLGMDGPYERERTFGSREPKQP 563
             A L P +   SS     S  F S+ G D + TL+PD  +   G  E      S      
Sbjct: 994  EATLSPGSTTASSLGQQ-STTFHSSPG-DTETTLLPDDTI-TSGLVEASTPTHSSTGSLH 1050

Query: 564  QPLLRKPSVSAQMQAYGQSSYSTQTWVRQQQMVVAHQYSFAPDGEARLVSRCPADNPGLV 623
              L    S SA +Q   + S + Q+W                              P   
Sbjct: 1051 TTLTPASSTSAGLQ---EESTTFQSW------------------------------PSSS 1077

Query: 624  QAQPRVPLTPTRGTSSRVAVQRGVGSGPHPPDTQQPSPSKAFKPRFPGDQVVNGAGPELS 683
               P  P T    T++ V V            T    PS      F       G   E +
Sbjct: 1078 DTTPSPPGT----TAAPVEVST----------TYHSRPSSTPTTHFSASSTTLGRSEEST 1123

Query: 684  T-GPSPGSPTLDIDQSIEQLNRLILELDPTFEPIP---THMNAL-GSQANGSVSPDSVGG 738
            T   SPG+    +  +    + L+ E  PT  PI    T   AL GS     +S  S   
Sbjct: 1124 TVHSSPGATGTALFPTRSATSVLVGE--PTTSPISSGSTETTALPGSTTTAGLSEKSTT- 1180

Query: 739  GLRASSRLPDTGEGPSRATG------------RQGSSAEQPLGGRLRKLSLGQYDNDAGG 786
               +S R PDT   P+  T             R GS+      G      + Q ++ A  
Sbjct: 1181 -FYSSPRSPDTTLSPASTTSSGVSEESTTSHSRPGSTHTTAFPGSTTMPGVSQ-ESTASH 1238

Query: 787  QLPFSKCAWGKAGVDYAPNLPP-----FPSPADVKETMTPGYPQDLDIIDGRILSSKESM 841
              P S       G   A +L P       SP   + T+ P       +++    +   S 
Sbjct: 1239 SSPGSTDTTLSPGSTTASSLGPESTTFHSSPGSTETTLLPDNTTASGLLEAS--TPVHSS 1296

Query: 842  CSTPAFPVSPETPYVK----TALRHPPFSP---PEPPLSSPASQHKGGREPRSCPETLTH 894
              +P   +SP     +    T  +  P S    P PP ++ A          S   T T 
Sbjct: 1297 TGSPHTTLSPAGSTTRQGESTTFQSWPSSKDTMPAPPTTTSAFVELSTTSHGSPSSTPTT 1356

Query: 895  AVGMSESPIGPKSTMLRADASSTPSFQQAFASSCTISSNGPGQRRESSSSAERQWVESSP 954
                S + +G      R++ S+T           T ++  P +   S    E     SSP
Sbjct: 1357 HFSASSTTLG------RSEESTTVHSSPV----ATATTPSPARSTTSGLVEESTAYHSSP 1406

Query: 955  KPMVSLLGSGRPTGSPLSAEFSGTRKDSPVLSCFPPSELQAPFHSHELSLAEPPDSLAPP 1014
                   GS +    P S+  SG  ++S          + +P  +    + EP    + P
Sbjct: 1407 -------GSTQTMHFPESSTASGRSEESRTSHSSTTHTISSPPSTTSALVEEPTSYHSSP 1459

Query: 1015 SSQAFLGFGTAPVGSGLPPEEDLGALLANSHGASPTPSIPLTATGAADNGFLSHNFLTVA 1074
             S A   F  +   SG   E        +++G +P P+   T+   A++         ++
Sbjct: 1460 GSIATTHFPESSTTSGRSEESTASHSSPDTNGITPLPAHFTTSGRIAES-----TTFYIS 1514

Query: 1075 PGH------SSHHSPGLQGQGV-----TLPGQP------PLPEKKRASEGDRSLGSVSPS 1117
            PG       S+  +PGL  +        L G+P      P P          S   ++  
Sbjct: 1515 PGSMETTLASTATTPGLSAKSTILYTSDLVGEPTTFYISPSPTYTTLFPASSSTSGLTEE 1574

Query: 1118 SSGF-SSPHSGSTI 1130
            S+ F +SP   STI
Sbjct: 1575 STTFHTSPSFTSTI 1588


>gi|91982772 mucin 17 [Homo sapiens]
          Length = 4493

 Score = 48.9 bits (115), Expect = 4e-05
 Identities = 117/513 (22%), Positives = 182/513 (35%), Gaps = 74/513 (14%)

Query: 681  ELSTGPSPGSPTLDIDQSIEQLNRLILELDPTFEPIPTHMNALGSQANGSVSPDSVGGGL 740
            E+S+ P+P   T  +  S     R  L    T  P+ T + A  + +  S +P      +
Sbjct: 842  EVSSSPTPAEGT-SMPTSTYSEGRTPL----TSMPVSTTLVATSAISTLSTTPVDTSTPV 896

Query: 741  RASSRL---PDTGEGPSRATGRQGS----------SAEQPLGGRLRKLSLGQYDNDAGGQ 787
              S+     P T EG S  T   G           S    +    R LS    D      
Sbjct: 897  TNSTEARSSPTTSEGTSMPTSTPGEGSTPLTSMPDSTTPVVSSEARTLSATPVDTST--P 954

Query: 788  LPFSKCAWGKAGVDYAPNLPPF-PSPADVKETMTPGYPQDLDIIDGRILSSKESMCSTPA 846
            +  S  A          ++P   PS      T TP       +    + +S+ S  ST  
Sbjct: 955  VTTSTEATSSPTTAEGTSIPTSTPSEGTTPLTSTP-------VSHTLVANSEASTLSTT- 1006

Query: 847  FPVSPETPYV-KTALRHPPFSPPEPPLSSPASQHKGGREPRSCPETLTHAVGMSESPIGP 905
             PV   TP    T    PP  P     S P S    G  P +     T  V  SE+    
Sbjct: 1007 -PVDSNTPLTTSTEASSPP--PTAEGTSMPTSTPSEGSTPLTRMPVSTTMVASSET---- 1059

Query: 906  KSTMLRADA-SSTP--SFQQAFASSCTISSNGPGQRRESSSSAERQWVESSPKPMVSLLG 962
             ST+    A +STP  ++ QA +SS T           S  S     V  S + +VS   
Sbjct: 1060 -STLSTTPADTSTPVTTYSQASSSSTTADGTSMPTSTYSEGSTPLTSVPVSTRLVVSSEA 1118

Query: 963  S---------GRPTGSPLSAEFSGTRKDSPVLSCFPPSELQAPFHSHELS----LAEPPD 1009
            S           P  +   A  S T  +   +   PPSE   P  S  +S    ++   +
Sbjct: 1119 STLSTTPVDTSIPVTTSTEASSSPTTAEGTSIPTSPPSEGTTPLASMPVSTTLVVSSEAN 1178

Query: 1010 SLAPPSSQAFLGFGTAPVGSGLPPEEDLGALLANSHGASPTP--SIPLTATGAADNGFLS 1067
            +L+     +     T+   S  PP  ++ ++  ++ G   TP  S+P+  T  A +    
Sbjct: 1179 TLSTTPVDSKTQVATSTEASSPPPTAEVTSMPTSTPGERSTPLTSMPVRHTPVASS---E 1235

Query: 1068 HNFLTVAPGHSSH--------HSPGLQGQGVTLPGQPPLPEKKRASEGDRSLGSVSPSSS 1119
             + L+ +P  +S          S     +G +LP           SEG   L S+  S++
Sbjct: 1236 ASTLSTSPVDTSTPVTTSAETSSSPTTAEGTSLP-------TSTTSEGSTLLTSIPVSTT 1288

Query: 1120 GFSSPHSGSTISIPFPNVLPDFSKASEAASPLP 1152
              +SP + + ++ P     P  +    ++SP P
Sbjct: 1289 LVTSPEASTLLTTPVDTKGPVVTSNEVSSSPTP 1321



 Score = 36.2 bits (82), Expect = 0.23
 Identities = 78/348 (22%), Positives = 126/348 (36%), Gaps = 50/348 (14%)

Query: 834  ILSSKESMCSTPAFPVSPETPYVKTALRHPPFSPPEPPLSSPASQHKGGREPRSCPETLT 893
            + SS+ S  ST   PV   TP   ++      + PE   S P S    G  P +     T
Sbjct: 523  VASSEASTLSTT--PVDTSTPVTTSSEASSSSTTPEGT-SIPTSTPSEGSTPLTNMPVST 579

Query: 894  HAVGMSESPI-----GPKSTMLRADASSTPSFQQAFASSCTISSNGPGQRRESSSSAERQ 948
              V  SE+          +T +   + ++ S   A  +S   S+        +S S    
Sbjct: 580  RLVVSSEASTTSTTPADSNTFVTTSSEASSSSTTAEGTSMPTSTYSERGTTITSMSVSTT 639

Query: 949  WVESSPKPMVSL--LGSGRPTGSPLSAEFSGTRKDSPVLSCFPPSELQAPFHSHELSLAE 1006
             V SS    +S   + S  P  +   A  S T  +   +     +E   P  S       
Sbjct: 640  LVASSEASTLSTTPVDSNTPVTTSTEATSSSTTAEGTSMPTSTYTEGSTPLTSM------ 693

Query: 1007 PPDSLAPPSSQAFLGFGTAPVGSGLP----------PEEDLGALLANS---HGASPTPSI 1053
            P ++    SS+A     T PV +  P          P    GA +  S    G++P  S+
Sbjct: 694  PVNTTLVASSEAST-LSTTPVDTSTPVTTSTEASSSPTTADGASMPTSTPSEGSTPLTSM 752

Query: 1054 PLTATGAADNGFLSHNFLTVAPGHSSHH---------SPGLQGQGVTLPGQPPLPEKKRA 1104
            P++ T    +     + L+  P  +S H         SP    +G ++P   P       
Sbjct: 753  PVSKTLLTSS---EASTLSTTPLDTSTHITTSTEASCSPTTT-EGTSMPISTP------- 801

Query: 1105 SEGDRSLGSVSPSSSGFSSPHSGSTISIPFPNVLPDFSKASEAASPLP 1152
            SEG   L S+  S +  +SP + +  + P  +  P  +    ++SP P
Sbjct: 802  SEGSPLLTSIPVSITPVTSPEASTLSTTPVDSNSPVTTSTEVSSSPTP 849



 Score = 35.8 bits (81), Expect = 0.31
 Identities = 77/375 (20%), Positives = 127/375 (33%), Gaps = 51/375 (13%)

Query: 810  PSPADVKETMTPGYPQ------DLDIIDGRILSSKESMCSTPAFPVSPETPYVKTALRHP 863
            P+PA+     T  Y +       + +    + SS  S+ ST   PV   TP V T+    
Sbjct: 1319 PTPAEGTSMPTSTYSEGRTPLTSIPVNTTLVASSAISILSTT--PVDNSTP-VTTSTEAC 1375

Query: 864  PFSPPEPPLSSPASQHKGGREP-RSCPETLTHAVGMSESPIGPKSTMLRADASSTPSFQQ 922
                     S P S    G  P  S P + T  V    S +           +STP    
Sbjct: 1376 SSPTTSEGTSMPNSNPSEGTTPLTSIPVSTTPVVSSEASTLSATPV-----DTSTPGTTS 1430

Query: 923  AFASSCTISSNGPGQRRESSSSAERQWVESSPKPMVSLLGSGRPTGSPLSAEFSGTRKDS 982
            A A+S   ++ G      + S  +         P+ S+  S  P  +  ++  S T  DS
Sbjct: 1431 AEATSSPTTAEGISIPTSTPSEGKT--------PLKSIPVSNTPVANSEASTLSTTPVDS 1482

Query: 983  --PVLSCFPPSELQAPFHSHELSLAEP----------PDSLAPPSSQAFLGFGTAPVGSG 1030
              PV++    S    P     ++++ P          P S    +S       T P  + 
Sbjct: 1483 NSPVVTSTAVSSSPTPAEGTSIAISTPSEGSTALTSIPVSTTTVASSEINSLSTTPAVTS 1542

Query: 1031 LP----------PEEDLGALLANS---HGASPTPSIPLTATGAADNGFLSHNFLTVAPGH 1077
             P          P    G  +  S    G++P  S+P++      +     N L+  P  
Sbjct: 1543 TPVTTYSQASSSPTTADGTSMQTSTYSEGSTPLTSLPVSTMLVVSS---EANTLSTTPID 1599

Query: 1078 SSHHSPGLQGQGVTLPGQPPLPEKKRASEGDRSLGSVSPSSSGFSSPHSGSTISIPFPNV 1137
            S            +   +         SEG   L S+  S++  +SP + +  + P  + 
Sbjct: 1600 SKTQVTASTEASSSTTAEGSSMTISTPSEGSPLLTSIPVSTTPVASPEASTLSTTPVDSN 1659

Query: 1138 LPDFSKASEAASPLP 1152
             P  +    ++SP P
Sbjct: 1660 SPVITSTEVSSSPTP 1674



 Score = 33.9 bits (76), Expect = 1.2
 Identities = 68/324 (20%), Positives = 112/324 (34%), Gaps = 67/324 (20%)

Query: 836  SSKESMCSTPAFPVSPETPYVKTALRHPPFSPPEPPLSSPASQHKGGREPRSCPETLTHA 895
            S   ++ +TPA   +P T Y + +           P S+P    + GR P +     T  
Sbjct: 1882 SETNTLSTTPAVTSTPVTTYAQVSSSPTTADGSSMPTSTP----REGRPPLTSIPVSTTT 1937

Query: 896  VGMSESPIGPKSTMLRADASSTPSFQQAFASSCTISSNGPGQRRESSSSAERQWVESSPK 955
            V  SE  I   ST L    +   ++ QA +S  T                      S P 
Sbjct: 1938 VASSE--INTLSTTLADTRTPVTTYSQASSSPTTADGT------------------SMPT 1977

Query: 956  PMVSLLGSGRPTGSPLSAEFSGTRKDSPVLSCFPPSELQAPFHSHELSLAEPPDSLAPPS 1015
            P  S  GS   T  PLS        ++  LS  P            +  + P  +    S
Sbjct: 1978 PAYSE-GSTPLTSMPLSTTLV-VSSEASTLSTTP------------VDTSTPATTSTEGS 2023

Query: 1016 SQAFLGFGTAPVGSGLPPEEDLGALLANSHGASPTPSIPLTATGAADNGFLSHNFLTVAP 1075
            S      GT+ + +  P E             +P   +P++ T    +     N L+  P
Sbjct: 2024 SSPTTAGGTS-IQTSTPSER-----------TTPLAGMPVSTTLVVSS---EGNTLSTTP 2068

Query: 1076 -------GHSSHHSPGLQGQGVTLPGQPPLPEKKRASEGDRSLGSVSPSSSGFSSPHSGS 1128
                    +S+  S     +G ++    P       SEG   L S+  S++  +SP + +
Sbjct: 2069 VDSKTQVTNSTEASSSATAEGSSMTISAP-------SEGSPLLTSIPLSTTPVASPEAST 2121

Query: 1129 TISIPFPNVLPDFSKASEAASPLP 1152
              + P  +  P  +    ++SP+P
Sbjct: 2122 LSTTPVDSNSPVITSTEVSSSPIP 2145



 Score = 32.0 bits (71), Expect = 4.4
 Identities = 71/328 (21%), Positives = 118/328 (35%), Gaps = 36/328 (10%)

Query: 834  ILSSKESMCSTPAFPVSPETPYVKTALRHPPFSPPEPPLSSPASQHKGGREP-RSCPETL 892
            +++S+ S  S  A PV   TP V T+             S P S    G  P  S P + 
Sbjct: 2232 VVTSEASTLS--ATPVDTSTP-VTTSTEATSSPTTAEGTSIPTSTLSEGTTPLTSIPVSH 2288

Query: 893  THAVG-----MSESPIGPKSTMLRA-DASSTPSFQQAFASSCTISSNG--PGQRR----- 939
            T         +S +P+   +    + +ASS P   +  +   + SS G  P  R      
Sbjct: 2289 TLVANSEVSTLSTTPVDSNTPFTTSTEASSPPPTAEGTSMPTSTSSEGNTPLTRMPVSTT 2348

Query: 940  -----ESSSSAERQWVESSPKPMVSLLGSGRPTGSPLSAEFSGTRKDSPVLSCFPPSELQ 994
                 E+S+ +      S+P    S  GS   T    S   S   + S  L+  P S + 
Sbjct: 2349 MVASFETSTLSTTPADTSTPVTTYSQAGSSPTTADDTSMPTSTYSEGSTPLTSVPVSTMP 2408

Query: 995  APFHSHELSLAEPPDSLAPPSSQAFLGFG-TAPVGSGLPPEEDLGALLANSHGASPTPSI 1053
                        P D+  P ++        T   G+ +P           S G +P  S+
Sbjct: 2409 VVSSEASTHSTTPVDTSTPVTTSTEASSSPTTAEGTSIPTSPP-------SEGTTPLASM 2461

Query: 1054 PLTATG--AADNGFLSHNFLTVAPGHSSHHSPGLQGQGVTLPGQPPLPEKKRASEGDRSL 1111
            P++ T   +++ G LS    T     S+  +   +        +  +     ASEG   L
Sbjct: 2462 PVSTTPVVSSEAGTLS----TTPVDTSTPMTTSTEASSSPTTAEDIVVPISTASEGSTLL 2517

Query: 1112 GSVSPSSSGFSSPHSGSTISIPFPNVLP 1139
             S+  S++  +SP + +  + P  +  P
Sbjct: 2518 TSIPVSTTPVASPEASTLSTTPVDSNSP 2545


>gi|163965366 nascent polypeptide-associated complex alpha subunit
            isoform a [Homo sapiens]
          Length = 2078

 Score = 48.9 bits (115), Expect = 4e-05
 Identities = 134/599 (22%), Positives = 191/599 (31%), Gaps = 83/599 (13%)

Query: 612  VSRCPADNPGLVQAQPRVPLTPTRGTSSRVAVQRGVGSGPHPPDTQQPSPSKAFKPRFPG 671
            VS  P ++P        +PL PT   +  VA        P P +T  P  +    P  P 
Sbjct: 681  VSLAPKNHPVKEGTLTTLPLVPTASENCPVA--------PSPQNTCAPLATLVLAPEIPK 732

Query: 672  DQVVNGAGPELSTGPSPGSPTLDIDQSIEQLNRLILELDPTFEPIPTHMNALGSQANG-- 729
                    P    G  PG+  +D    I   + L        E  PT  +   + A+   
Sbjct: 733  SVPSPSLPP---AGTPPGTKKVD---GISHTSALAPVASSPKE-CPTEDSGASATASSKG 785

Query: 730  -----SVSPDSVGGGLRASSRLPDTGEG---PSRATGRQGSSAEQPLGGRLRKLSL---G 778
                 + SP  +G  +   ++ P T +G   P    G   S         L + SL   G
Sbjct: 786  TLTYLADSPSPLGVSVSPQTKRPPTKKGSAGPDTPIGNLSSPVSPVEASFLPENSLSFQG 845

Query: 779  QYDNDA-----------GGQLPFSKCAWGKAGVDYAPNLPPFPSPADV---KETMTPGYP 824
              D+ A           G   P +       GV   P   P PS  ++   KE      P
Sbjct: 846  SKDSPATTHSPTPPSPKGAPTPSAVTPLSPKGVTLPPKETPTPSVVNLPFPKEGPATPAP 905

Query: 825  QDLDIIDGRILSSKESMCSTPAFPVSPETPYVKTALRHPPFSPPE--------------- 869
            +    +     SS +   +TPA    P +P  K A   P  +PP                
Sbjct: 906  KQAPALS-MTSSSPKKARATPAPKGIPASPSPKGAPTPPAATPPSPKGGPATPSPKWAPT 964

Query: 870  PPLSSPASQHKGGREPRSCPETLTHAVGMSESPIGPKSTMLRADASSTPSFQQAFASSCT 929
            PP ++P S  KGG    S     T       SP G  +T     A + P+          
Sbjct: 965  PPAATPPSP-KGGPATPSPKGAPTPPAATPPSPKGGPATPSPKGAPTPPAVTPPSPKGSP 1023

Query: 930  ISSNGPGQRRESSSSAERQWVESSPK--PMVSLLGSGRPT------GSPLSAEFSGTRKD 981
             ++  P       +S        SPK  P  + L  G PT       SP     + + K 
Sbjct: 1024 AATPFP-----KGASTPPAATPPSPKGSPAATPLPKGAPTTPAATLPSPKGGPATPSLKG 1078

Query: 982  SPV-LSCFPPSELQAPFHSHELSLAEPPDSLAPPSSQAFLGF----GTAPVGSGLPPEED 1036
            +P   +  PPS    P          PP +  PPS +  L      G     +  PP   
Sbjct: 1079 APTPPAATPPSPKGGPATPSPKGAPMPP-AATPPSPKGGLATPPHKGAPTTPAATPPSPK 1137

Query: 1037 LGALLANSHGASPTPSIPLTATGAADNGFLSHNFLTVAPGHSSHHSPGLQGQGVTLPGQP 1096
             G       GA  TP+    AT  +  G L+      AP   +   P  +G G+  P   
Sbjct: 1138 GGLATPPPKGAPTTPA----ATPPSPKGGLATPPPKGAPTTPAATPPSPKG-GLATPSPK 1192

Query: 1097 PLPEKKRASEGDRSLGSVSPSSSGFSSPHSGSTISIPFPNVLPDFSKASEAASPLPDSP 1155
              P    A+      G  +PS  G  +  + +  S       P    A    +  P SP
Sbjct: 1193 GAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSP 1251



 Score = 40.4 bits (93), Expect = 0.012
 Identities = 83/330 (25%), Positives = 113/330 (34%), Gaps = 50/330 (15%)

Query: 843  STPAFPVS-PETPYVKTALRHPPFSPPEP---------------PLSSPASQHKGG---R 883
            +TP  P   P TP  K A   P  +PP P               P ++P S  KGG    
Sbjct: 1085 ATPPSPKGGPATPSPKGAPMPPAATPPSPKGGLATPPHKGAPTTPAATPPSP-KGGLATP 1143

Query: 884  EPRSCPETLTHAVGMSESPIGPKSTMLRADASSTPSFQQAFASSCTISSNGPGQRRESSS 943
             P+  P T         SP G  +T     A +TP        + T  S   G    S  
Sbjct: 1144 PPKGAPTT---PAATPPSPKGGLATPPPKGAPTTP--------AATPPSPKGGLATPSPK 1192

Query: 944  SAERQWVESSPKPMVSLLGSGRPTGSPLSAEFSGTRKDSPVLSCFPPSELQAPFHSHELS 1003
             A      + P P    L +  P G+P +         SP      PS   AP       
Sbjct: 1193 GAPTTPAATPPSPKGG-LATPSPKGAPTT---PAATPPSPKGGLATPSPKGAP----TTP 1244

Query: 1004 LAEPPDSLAPPSSQAFLGFGTAPVGSGLPPEEDLGALLANSHGASPTPSIPLTATGAADN 1063
             A PP     P++    G  T P  +   P    G L    H  +P P++    T  +  
Sbjct: 1245 AATPPSPKGGPATPPPKGAPTPPAAT---PPSLKGGLATPPHKGAPNPAV---VTPPSPK 1298

Query: 1064 GFLSHNFLTVAPGHSSHHSPGLQGQGVTLP--GQPPLPEKKRAS-EGDRSLGSVSPSSSG 1120
            G  + +    AP   +   P  +G   T P  G P  P     S +G  +L + +PSS G
Sbjct: 1299 GGPATSPPKGAPTPPAATPPSPKGSPGTPPPKGAPTPPAVTPPSPKGTPTLPATTPSSKG 1358

Query: 1121 FSSPHSGSTISIPFPNVLPDFSKASEAASP 1150
               P + S+   P P       K   A +P
Sbjct: 1359 --GPTTPSSKEGPTPPAATPSHKGGPAMTP 1386



 Score = 39.3 bits (90), Expect = 0.028
 Identities = 126/551 (22%), Positives = 196/551 (35%), Gaps = 63/551 (11%)

Query: 616  PADNPGLVQAQPRVPLTPTRGTSSRVAVQRGVGSGPHPPDTQQPSPSKAFKPRFPGDQVV 675
            P+   G   + P+   TP   T          GS   PP    P+P     P   G   +
Sbjct: 1295 PSPKGGPATSPPKGAPTPPAATPPSPK-----GSPGTPPPKGAPTPPAVTPPSPKGTPTL 1349

Query: 676  NGAGPELSTGP-SPGSPTLDIDQSIEQLNRLILELDPTFEPIPTHMNALGSQANGSVSPD 734
                P    GP +P S       +    ++    + P   P P    A+ S      SP 
Sbjct: 1350 PATTPSSKGGPTTPSSKEGPTPPAATPSHKGGPAMTP---PSPKRGPAIPSPKGDPTSPA 1406

Query: 735  SVGGGLRASSRLPDTGEGPSRATGRQGSSAEQPLGGRLRKLSLGQYDNDAGGQLPFSKCA 794
             +    + +   P T EG   AT  +G      +     K +        G   P SK  
Sbjct: 1407 VIPLSPKKAPATPVTREG--AATPSKGDLTPPAVTPVSLKKAPATSAPKGGPATPSSK-- 1462

Query: 795  WGKAGVDYAPNLPPFPSPADVKETMTPGYPQDLDIIDGRILSSKESMCSTPAFPVSPETP 854
                G    P + P PSP +      P  P+ +        SS +   +TPA   +P  P
Sbjct: 1463 ----GDPTLPAVTP-PSPKE------PPAPKQV-----ATSSSPKKAPATPAPMGAPTLP 1506

Query: 855  YVKTALRHPPFSPPEPPLSSPASQHKGGREPRSCPETLTHAVGMSESPIGPKSTMLRADA 914
             V       P SP E P ++P+S+    R+P +   TL      + + + PK  ++   A
Sbjct: 1507 AV------IPSSPKEVP-ATPSSR----RDPIAPTATLLSK--KTPATLAPKEALI-PPA 1552

Query: 915  SSTPSFQQAFASSCTISSNGPGQRRESSS--SAERQWVESSPKPMVSLLGSGRPTGSPLS 972
             + PS ++  A      +      +E+SS  +      + +P P   L+     + SP  
Sbjct: 1553 MTVPSPKKTPAIPTPKEAPATPSSKEASSPPAVTPSTYKGAPSPKELLIPPAVTSPSPKE 1612

Query: 973  AEF-SGTRKDSPVLSCFPPSELQAPFHSHELSLAEPPDSLAPPSSQAFLGFGTAPVGS-G 1030
            A         SP      P+    P  S  ++ +   DS   P+S       T P  S G
Sbjct: 1613 APTPPAVTPPSPEKGPATPAPKGTP-TSPPVTPSSLKDSPTSPASVTCKMGATVPQASKG 1671

Query: 1031 LPPEEDLGALLANSHGASP--TPSIPLTATGAADNGFLSHNFLTVAPGHSSHHSPGLQGQ 1088
            LP ++   AL       +P  TP I             S     + P  S+ +  G +G 
Sbjct: 1672 LPAKKGPTALKEVLVAPAPESTPIITAPTRKGPQTKKSSATSPPICPDPSAKN--GSKGP 1729

Query: 1089 GVTLPGQPPLPEKKRASEGDRS-------LGSVSPSSSGFSSPHSGSTISIPFPNVLPDF 1141
              T+   P LP +K +S+  +         G ++P  S  S+P + +     F  VLP  
Sbjct: 1730 LSTVAPAPLLPVQKDSSKTAKGKDASHSPKGPLAPPESKASTPLTAAA----FEKVLPKP 1785

Query: 1142 SKASEAASPLP 1152
              AS +A+P P
Sbjct: 1786 ESASVSAAPSP 1796



 Score = 37.7 bits (86), Expect = 0.081
 Identities = 88/326 (26%), Positives = 134/326 (41%), Gaps = 43/326 (13%)

Query: 837  SKESMCSTPAFPVSPETPYVKTALRHP-PFSPPEPPLSSPASQHKGGREPRSCPETLTHA 895
            S +S  S+P  P+SPE    K +L  P P   P   ++SP     G     S  +T ++A
Sbjct: 572  SFQSTSSSPEIPLSPEATLAKKSLGEPLPIGKPASSMTSPL----GVNSSASVIKTDSYA 627

Query: 896  VGMSESPIGPKSTMLRADASSTPSFQQAFASSCTISSNGPGQRRESSSSAERQWVESSPK 955
               S  P+  KS+++    ++ P      A     ++ G      ++S      V  +PK
Sbjct: 628  GPDSAGPL-LKSSLITPTVAAFPLESADPAGVAPTTAKGTSTYTTTASPFLEGTVSLAPK 686

Query: 956  PMVSLLGSGRPTGSPL--SAEFSGTRKDSPVLSCFPPSELQAPFHSHELSLAEPPDSLAP 1013
                 +  G  T  PL  +A  +     SP  +C P + L     + E+  + P  SL P
Sbjct: 687  N--HPVKEGTLTTLPLVPTASENCPVAPSPQNTCAPLATLVL---APEIPKSVPSPSLPP 741

Query: 1014 PSSQAFLGFGTAPVGSGLPPEEDLGALLANSHGASPTPSIPLTATGAADNGFLSHNFLTV 1073
              +      GT  V  G+     L A +A+S    PT     +AT A+  G L+  +L  
Sbjct: 742  AGTPP----GTKKV-DGISHTSAL-APVASSPKECPTEDSGASAT-ASSKGTLT--YLAD 792

Query: 1074 APGHSSHHSPGLQGQGVTLPGQPPLPEKKRASEG-DRSLGSVSPSSSGFSSPHSGSTIS- 1131
            +P      SP     GV++  Q   P  K+ S G D  +G++       SSP S    S 
Sbjct: 793  SP------SP----LGVSVSPQTKRPPTKKGSAGPDTPIGNL-------SSPVSPVEASF 835

Query: 1132 IPFPNVLPDFSKASEAA--SPLPDSP 1155
            +P  ++    SK S A   SP P SP
Sbjct: 836  LPENSLSFQGSKDSPATTHSPTPPSP 861



 Score = 37.7 bits (86), Expect = 0.081
 Identities = 120/532 (22%), Positives = 173/532 (32%), Gaps = 74/532 (13%)

Query: 651  PHPPDTQQPSPSKAFK-PRFPGDQVVNGAGPE-----LSTGPSPGSPTLDIDQSIEQLNR 704
            P PP    PSP      P   G      A P      L+T P  G+PT            
Sbjct: 1103 PMPPAATPPSPKGGLATPPHKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGG 1162

Query: 705  LILELDPTFEPIPTHMNALGSQANGSVSPDSVGGGLRASSRLPDTGEG------PSRATG 758
            L     P  +  PT   A      G ++  S  G     +  P + +G      P  A  
Sbjct: 1163 LAT---PPPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPT 1219

Query: 759  RQGSSAEQPLGGRLRKLSLGQYDNDAGGQLPFSKCAWGKAGVDYAPNLPPFPSPADVKET 818
               ++   P GG      L           P +     K G    P  PP P  A     
Sbjct: 1220 TPAATPPSPKGG------LATPSPKGAPTTPAATPPSPKGG----PATPP-PKGAPTPPA 1268

Query: 819  MTPGYPQDLDIIDGRILSSKESMCSTPAFPVSPETPYVKTALRHPPFSPPEPPLSSPASQ 878
             TP        + G + +        PA  V+P +P    A   PP   P PP ++P S 
Sbjct: 1269 ATP------PSLKGGLATPPHKGAPNPAV-VTPPSPKGGPATS-PPKGAPTPPAATPPSP 1320

Query: 879  H--KGGREPRSCPETLTHAVGMSESPIG----PKSTMLRADASSTPSFQQAFASSCTISS 932
                G   P+  P   T       SP G    P +T       +TPS ++         S
Sbjct: 1321 KGSPGTPPPKGAP---TPPAVTPPSPKGTPTLPATTPSSKGGPTTPSSKEGPTPPAATPS 1377

Query: 933  NGPGQRRESSSSAERQWVESSPK-----PMVSLLGSGRPTGSPLSAEFSGTRKDSPVLSC 987
            +  G    +  S +R     SPK     P V  L   +   +P++ E + T     +   
Sbjct: 1378 HKGGPAM-TPPSPKRGPAIPSPKGDPTSPAVIPLSPKKAPATPVTREGAATPSKGDLT-- 1434

Query: 988  FPPSELQAPFHSHELSLAEPPDSLAP---PSSQAFLGFGTAP-VGSGLPPEEDLGALLAN 1043
             PP+          +SL + P + AP   P++ +  G  T P V    P E      +A 
Sbjct: 1435 -PPAVTP-------VSLKKAPATSAPKGGPATPSSKGDPTLPAVTPPSPKEPPAPKQVAT 1486

Query: 1044 SHGASPTPSIPLTATGAADNGFLSHNFLTVAPGHSSHHSPGLQGQGVTLPGQPPLPEKKR 1103
            S      P+ P           +  +   V    SS   P         P    L +K  
Sbjct: 1487 SSSPKKAPATPAPMGAPTLPAVIPSSPKEVPATPSSRRDP-------IAPTATLLSKKTP 1539

Query: 1104 ASEGDRSLGSVSPSSSGFSSPHSGSTISIPFPNVLPDFSKASEAASPLPDSP 1155
            A+   +   ++ P +    SP    T +IP P   P    + EA+SP   +P
Sbjct: 1540 ATLAPKE--ALIPPAMTVPSPKK--TPAIPTPKEAPATPSSKEASSPPAVTP 1587



 Score = 31.6 bits (70), Expect = 5.8
 Identities = 84/375 (22%), Positives = 124/375 (33%), Gaps = 64/375 (17%)

Query: 808  PFPSPADVKET-MTPGYPQDLDIIDGRILSSKESMCSTPAFPV--SPETPYVKTALRHPP 864
            PFPSP+ +  T +   +PQ                 S  A P+  +PE P     L  PP
Sbjct: 66   PFPSPSTIASTPLEVPFPQS---------------SSGTALPLGTAPEAPTFLPNLIGPP 110

Query: 865  FSPPEPPLSSP-ASQHKGGREPRSCPETLTHAVGMSESPIGPKSTMLRADASSTPSFQQA 923
             SP    L+SP  +    G    S P  L   V ++   +  KS+    +  ++P     
Sbjct: 111  ISPAALALASPMIAPTLKGTPSSSAPLAL---VALAPHSV-QKSSAFPPNLLTSPPSVAV 166

Query: 924  FASSCTISSNGPGQRRESSSSAERQWVESSPKPMVSLLGSGRPTGSPLSAEFSGTRKDSP 983
              S   I+ + P    E  ++  +   E  P P        + T SP            P
Sbjct: 167  AESGSVITLSAPIAPSEPKTNLNKVPSEVVPNP--------KGTPSP------------P 206

Query: 984  VLSCFPPSELQAPFHSHELSLAEPPDSLAPPSSQAFLG--FGTAPVGSGLPPEEDLGALL 1041
             +    P     P  S +  +A  P +  P ++ A          + S L   ++ G+L 
Sbjct: 207  CIVSTVPYHCVTPMASIQSGVASLPQT-TPTTTLAIASPQVKDTTISSVLISPQNPGSLS 265

Query: 1042 ANSHGASP------TPSIPLTATGAADNG------FLSHNFLTVAPGHSSHHSPGLQGQG 1089
                 + P      T S+P+  +     G      F       +AP H S     +Q  G
Sbjct: 266  LKGPVSPPAALSLSTQSLPVVTSSQKTAGPNTPPDFPISLGSHLAPLHQSSFG-SVQLLG 324

Query: 1090 VTLPGQPPLPEKKRASEGDRSLGSVSPSSSGFSSPHSGSTISIP-----FPNVLPDFSKA 1144
             T P     P  K  S    S G+  PS      P       +P     FP V P   K 
Sbjct: 325  QTGPSALSDPTVKTISVDHSSTGASYPSQRSVIPPLPSRNEVVPATVAAFPVVAPSVDKG 384

Query: 1145 SEAASPLPDSPGDKL 1159
                S +  SP   L
Sbjct: 385  PSTISSITCSPSGSL 399


>gi|54860105 nadrin isoform 2 [Homo sapiens]
          Length = 803

 Score = 48.5 bits (114), Expect = 5e-05
 Identities = 76/308 (24%), Positives = 113/308 (36%), Gaps = 46/308 (14%)

Query: 871  PLSSPASQHK--------GGREPRSCPETLTHAVG---MSESPIGPKSTMLRA------- 912
            PL++P+S H          G   R  P ++    G     ESP  PK  +  A       
Sbjct: 456  PLTTPSSNHSFHTGNDSDSGTLERKRPASMAVMEGDLVKKESPPKPKDPVSAAVPAPGRN 515

Query: 913  --DASSTPSFQQAFASSCTISSNGPGQRRESSSSAERQWVESSPKPMVSLLGSGRPTGSP 970
                +S  +  QA A S  +S   P      S    R+ V+  P P     G+  P G P
Sbjct: 516  NSQIASGQNQPQAAAGSHQLSMGQPHNAAGPSPHTLRRAVKK-PAPAPPKPGNP-PPGHP 573

Query: 971  LSAEFSGTRKDSPVLSCFPPSELQAPFHSHELSLAEPPDSLAPPSSQAFLGFGTAPVGSG 1030
                 SGT +  P LS  PP+   +P   H     +PP   + PS  +          S 
Sbjct: 574  GGQSSSGTSQHPPSLSPKPPTRSPSPPTQH---TGQPPGQPSAPSQLS----APRRYSSS 626

Query: 1031 LPPEEDLGALLANSH--GASPTPSIPLTATGAADNGFLSHNFLTVAPGHSSHHSPGLQGQ 1088
            L P      + A +H     PT + PL  T     G    N + +   H          Q
Sbjct: 627  LSP------IQAPNHPPPQPPTQATPLMHTKPNSQG--PPNPMALPSEHGLEQPSHTPPQ 678

Query: 1089 GVTLPGQPPLPEKKRASEGDRSLGSVSPSSSGFSSPHSGSTISIPFPNVLPDFSKASEAA 1148
              T P  PPL ++  +    ++L   +P +   + PH+G   ++P P  +P   +   + 
Sbjct: 679  TPTPPSTPPLGKQNPSLPAPQTLAGGNPET---AQPHAG---TLPRPRPVPK-PRNRPSV 731

Query: 1149 SPLPDSPG 1156
             P P  PG
Sbjct: 732  PPPPQPPG 739



 Score = 39.3 bits (90), Expect = 0.028
 Identities = 74/293 (25%), Positives = 99/293 (33%), Gaps = 33/293 (11%)

Query: 710 DPTFEPIPTHMNALGSQANGSVSPDSVGGGLRASSRLPDTGEGPSRATGRQGSSAEQPLG 769
           DP    +P         A+G   P +  G  + S   P    GPS  T R+      P  
Sbjct: 503 DPVSAAVPAPGRNNSQIASGQNQPQAAAGSHQLSMGQPHNAAGPSPHTLRRAVKKPAPAP 562

Query: 770 GRLRKLSLGQYDNDAGGQLPFSKCAWGKAGVDYAPNLPP-FPSPADVKETMTPGYPQDLD 828
            +      G      GGQ   S     +     +P  P   PSP        PG P    
Sbjct: 563 PKPGNPPPGH----PGGQ---SSSGTSQHPPSLSPKPPTRSPSPPTQHTGQPPGQPSAPS 615

Query: 829 IIDG-RILSSKESMCSTPAFPVSPETPYVKTALRH--PPFSPPEPPLSSPASQHKGGREP 885
            +   R  SS  S    P  P  P+ P   T L H  P    P  P++ P S+H   +  
Sbjct: 616 QLSAPRRYSSSLSPIQAPNHP-PPQPPTQATPLMHTKPNSQGPPNPMALP-SEHGLEQPS 673

Query: 886 RSCPETLTHAVGMSESPIGPKSTMLRAD---ASSTPSFQQAFASSCTISSNGPGQRRESS 942
            + P+T T     S  P+G ++  L A    A   P   Q  A +       P  R   S
Sbjct: 674 HTPPQTPTPP---STPPLGKQNPSLPAPQTLAGGNPETAQPHAGTLPRPRPVPKPRNRPS 730

Query: 943 SSAERQWVESSPKPM------VSLLGSGRPTGSPLSAEFSGTRKDSPVLSCFP 989
                  V   P+P        S L +  PT S +  + S +R   P  S FP
Sbjct: 731 -------VPPPPQPPGVHSAGDSSLTNTAPTASKIVTD-SNSRVSEPHRSIFP 775


>gi|31324577 molecule interacting with Rab13 [Homo sapiens]
          Length = 863

 Score = 48.5 bits (114), Expect = 5e-05
 Identities = 111/502 (22%), Positives = 170/502 (33%), Gaps = 79/502 (15%)

Query: 711  PTFEPIPTHMNALGSQANGSVSPDSVGGGLRASSRLPDTGEGPSRATGRQGSSAEQP-LG 769
            P  +P   H   L   A      D  GGG  +S+      +GP  +   +     +P + 
Sbjct: 233  PFSQPKQQHQQQLAEDAK-----DVPGGGPSSSAPAGAEADGPKASPEARPQIPTKPRVP 287

Query: 770  GRLRKLSLGQYDNDAGGQLPFSKCAWGKAGVDYAPNLPPFPSP-ADVKETMTPGYPQDLD 828
            G+L++L+       AG   P  +    KA     P  PP P P + +++           
Sbjct: 288  GKLQELA----SPPAGRPTPAPR----KASESTTP-APPTPRPRSSLQQENLVEQAGSSS 338

Query: 829  IIDGRI--------LSSKESMCSTPAFPVSPETPYV--------KTALRHPPFSPPEPPL 872
            +++GR+          + +    TPA    P  P++        K     PP S P PP 
Sbjct: 339  LVNGRLHELPVPKPRGTPKPSEGTPAPRKDP--PWITLVQAEPKKKPAPLPPSSSPGPPS 396

Query: 873  SSPASQHKGGREPRSCPETLTHAVGMSESPIGPKSTMLRADASSTPSFQQAFASSCTISS 932
                    GG E  + P           +P   +      +A + PS             
Sbjct: 397  QDSRQVENGGTEEVAQPSPTASLESKPYNPFEEEEEDKEEEAPAAPSL------------ 444

Query: 933  NGPGQRRESSSSAERQWVESSPKPMVSLLGSGRPTGSPLSAEFSGTRKDSPVLSCFPPSE 992
                     ++S      ES+PK +    G   PT SP + +    R          PS 
Sbjct: 445  ---------ATSPALGHPESTPKSLHPWYGI-TPTSSPKTKKRPAPR---------APSA 485

Query: 993  LQAPFHSHELSLAEPPDSLAPPS-SQAFLGFGTAPVGSGLPPEEDLGALLANSHGASPTP 1051
                 H+  LS +EPP +   P+ S   L   +A   +G    E      ++S  A   P
Sbjct: 486  SPLALHASRLSHSEPPSATPSPALSVESLSSESASQTAGAELLEPPAVPKSSSEPAVHAP 545

Query: 1052 SIPLTATGAADNGFLSHNFLTVAP--GHSSHHSPGLQGQGVTLPGQPPLPEKKRASE--- 1106
              P      + N  L+ +   V P        SPGL  +     G  P      A+    
Sbjct: 546  GTPGNPVSLSTNSSLASSGELVEPRVEQMPQASPGLAPRTRGSSGPQPAKPCSGATPTPL 605

Query: 1107 ---GDR----SLGSVSPSSSGFSSPHSGSTISIPFPNVLPDFSKASEAASPL-PDSPGDK 1158
               GDR    S GS SP     SS         P P   P   KA++ + P+ P +PG  
Sbjct: 606  LLVGDRSPVPSPGSSSPQLQVKSSCKENPFNRKPSPAASPATKKATKGSKPVRPPAPGHG 665

Query: 1159 LVIVKFVQDTSKFWYKADISRE 1180
              ++K      ++  + DI  E
Sbjct: 666  FPLIKRKVQADQYIPEEDIHGE 687


>gi|68989256 ras inhibitor RIN1 [Homo sapiens]
          Length = 783

 Score = 48.1 bits (113), Expect = 6e-05
 Identities = 51/180 (28%), Positives = 81/180 (45%), Gaps = 29/180 (16%)

Query: 1105 SEGDRSLGSV-SPSSSGFSSPHSGSTISIPFPNVLPDFSKASEAASPLPDSPGDKLVIVK 1163
            S G+   GS  +PS S F++ H       P  + L D   AS   +  P  PG  + + +
Sbjct: 3    SPGESGAGSPGAPSPSSFTTGHLAR--EKPAQDPLYDVPNASGGQAGGPQRPGRVVSLRE 60

Query: 1164 FVQDTSKFWYKADISREQAIAMLKDKEPGSFIVRDSHSFRGAYGLAMKV--ATPPPSVLQ 1221
             +  T   W +   +   A+ ML+ + PG+F+VR S++ R    L M++  A+ P  V  
Sbjct: 61   RLLLTRPVWLQLQANAAAALHMLRTEPPGTFLVRKSNT-RQCQALCMRLPEASGPSFVSS 119

Query: 1222 LNKKAGDLANELVRHFLIECTPKGVRLKGCSNEPYFGSLTALVCQHSIT------PLALP 1275
                          H+++E +P GV L+G  +E  F  L  L+C +  T      PL LP
Sbjct: 120  --------------HYILE-SPGGVSLEG--SELMFPDLVQLICAYCHTRDILLLPLQLP 162


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.314    0.132    0.392 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 66,222,088
Number of Sequences: 37866
Number of extensions: 3691551
Number of successful extensions: 13456
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 69
Number of HSP's successfully gapped in prelim test: 509
Number of HSP's that attempted gapping in prelim test: 11764
Number of HSP's gapped (non-prelim): 1964
length of query: 1445
length of database: 18,247,518
effective HSP length: 115
effective length of query: 1330
effective length of database: 13,892,928
effective search space: 18477594240
effective search space used: 18477594240
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 68 (30.8 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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