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Search of human proteins with 63999576
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|63999576 solute carrier family 22, member 17 isoform b [Homo
sapiens]
(520 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|63999576 solute carrier family 22, member 17 isoform b [Homo ... 1047 0.0
gi|21361834 solute carrier family 22, member 17 isoform a [Homo ... 1032 0.0
gi|239745643 PREDICTED: hypothetical protein LOC146429 isoform 1... 283 2e-76
gi|239751156 PREDICTED: hypothetical protein LOC146429 isoform 6... 280 3e-75
gi|170650643 solute carrier family 22, member 23 isoform a [Homo... 261 1e-69
gi|48526516 solute carrier family 22, member 23 isoform b [Homo ... 213 4e-55
gi|239756672 PREDICTED: hypothetical protein LOC146429 [Homo sap... 194 1e-49
gi|11415038 solute carrier family 22 member 3 [Homo sapiens] 143 4e-34
gi|166064021 solute carrier family 22 (organic anion transporter... 135 9e-32
gi|4506999 solute carrier family 22 member 1 isoform a [Homo sap... 125 7e-29
gi|24497499 solute carrier family 22 member 8 [Homo sapiens] 125 7e-29
gi|90669191 solute carrier family 22 member 7 isoform b [Homo sa... 125 9e-29
gi|24497476 solute carrier family 22 member 6 isoform b [Homo sa... 125 1e-28
gi|24497497 solute carrier family 22 member 7 isoform a [Homo sa... 124 2e-28
gi|4507001 solute carrier family 22 member 2 [Homo sapiens] 124 3e-28
gi|20070188 solute carrier family 22 member 6 isoform a [Homo sa... 123 5e-28
gi|42542386 solute carrier family 22 (organic anion/cation trans... 120 4e-27
gi|24497485 urate anion exchanger 1 isoform a [Homo sapiens] 119 7e-27
gi|153791484 putative UST1-like organic anion transporter [Homo ... 118 1e-26
gi|211059435 solute carrier family 22, member 24 [Homo sapiens] 113 4e-25
gi|238814326 solute carrier family 22, member 20 [Homo sapiens] 112 8e-25
gi|148664184 solute carrier family 22, member 10 [Homo sapiens] 111 1e-24
gi|24497480 solute carrier family 22 member 6 isoform d [Homo sa... 106 6e-23
gi|24497478 solute carrier family 22 member 6 isoform c [Homo sa... 106 6e-23
gi|23510410 solute carrier family 22 member 1 isoform b [Homo sa... 103 4e-22
gi|8923870 solute carrier family 22 member 11 [Homo sapiens] 103 5e-22
gi|31542327 solute carrier family 22, member 16 [Homo sapiens] 103 5e-22
gi|4507005 solute carrier family 22 member 5 [Homo sapiens] 102 8e-22
gi|166197673 solute carrier family 22, member 15 [Homo sapiens] 100 5e-21
gi|24497490 solute carrier family 22 member 4 [Homo sapiens] 91 2e-18
>gi|63999576 solute carrier family 22, member 17 isoform b [Homo
sapiens]
Length = 520
Score = 1047 bits (2707), Expect = 0.0
Identities = 520/520 (100%), Positives = 520/520 (100%)
Query: 1 MASDPIFTLAPPLHCHYGAFPPNASGWEQPPNASGVSVASAALAASAASRVATSTDPSCS 60
MASDPIFTLAPPLHCHYGAFPPNASGWEQPPNASGVSVASAALAASAASRVATSTDPSCS
Sbjct: 1 MASDPIFTLAPPLHCHYGAFPPNASGWEQPPNASGVSVASAALAASAASRVATSTDPSCS 60
Query: 61 GFAPPDFNHCLKDWDYNGLPVLTTNAIGQWDLVCDLGWQVILEQILFILGFASGYLFLGY 120
GFAPPDFNHCLKDWDYNGLPVLTTNAIGQWDLVCDLGWQVILEQILFILGFASGYLFLGY
Sbjct: 61 GFAPPDFNHCLKDWDYNGLPVLTTNAIGQWDLVCDLGWQVILEQILFILGFASGYLFLGY 120
Query: 121 PADRFGRRGIVLLTLGLVGPCGVGGAAAGSSTGVMALRFLLGFLLAGVDLGVYLMRLELC 180
PADRFGRRGIVLLTLGLVGPCGVGGAAAGSSTGVMALRFLLGFLLAGVDLGVYLMRLELC
Sbjct: 121 PADRFGRRGIVLLTLGLVGPCGVGGAAAGSSTGVMALRFLLGFLLAGVDLGVYLMRLELC 180
Query: 181 DPTQRLRVALAGELVGVGGHFLFLGLALVSKDWRFLQRMITAPCILFLFYGWPGLFLESA 240
DPTQRLRVALAGELVGVGGHFLFLGLALVSKDWRFLQRMITAPCILFLFYGWPGLFLESA
Sbjct: 181 DPTQRLRVALAGELVGVGGHFLFLGLALVSKDWRFLQRMITAPCILFLFYGWPGLFLESA 240
Query: 241 RWLIVKRQIEEAQSVLRILAERNRPHGQMLGEEAQEALQDLENTCPLPATSSFSFASLLN 300
RWLIVKRQIEEAQSVLRILAERNRPHGQMLGEEAQEALQDLENTCPLPATSSFSFASLLN
Sbjct: 241 RWLIVKRQIEEAQSVLRILAERNRPHGQMLGEEAQEALQDLENTCPLPATSSFSFASLLN 300
Query: 301 YRNIWKNLLILGFTNFIAHAIRHCYQPVGGGGSPSDFYLCSLLASGTAALACVFLGVTVD 360
YRNIWKNLLILGFTNFIAHAIRHCYQPVGGGGSPSDFYLCSLLASGTAALACVFLGVTVD
Sbjct: 301 YRNIWKNLLILGFTNFIAHAIRHCYQPVGGGGSPSDFYLCSLLASGTAALACVFLGVTVD 360
Query: 361 RFGRRGILLLSMTLTGIASLVLLGLWDYLNEAAITTFSVLGLFSSQAAAILSTLLAAEVI 420
RFGRRGILLLSMTLTGIASLVLLGLWDYLNEAAITTFSVLGLFSSQAAAILSTLLAAEVI
Sbjct: 361 RFGRRGILLLSMTLTGIASLVLLGLWDYLNEAAITTFSVLGLFSSQAAAILSTLLAAEVI 420
Query: 421 PTTVRGRGLGLIMALGALGGLSGPAQRLHMGHGAFLQHVVLAACALLCILSIMLLPETKR 480
PTTVRGRGLGLIMALGALGGLSGPAQRLHMGHGAFLQHVVLAACALLCILSIMLLPETKR
Sbjct: 421 PTTVRGRGLGLIMALGALGGLSGPAQRLHMGHGAFLQHVVLAACALLCILSIMLLPETKR 480
Query: 481 KLLPEVLRDGELCRRPSLLRQPPPTRCDHVPLLATPNPAL 520
KLLPEVLRDGELCRRPSLLRQPPPTRCDHVPLLATPNPAL
Sbjct: 481 KLLPEVLRDGELCRRPSLLRQPPPTRCDHVPLLATPNPAL 520
>gi|21361834 solute carrier family 22, member 17 isoform a [Homo
sapiens]
Length = 538
Score = 1032 bits (2669), Expect = 0.0
Identities = 519/538 (96%), Positives = 519/538 (96%), Gaps = 18/538 (3%)
Query: 1 MASDPIFTLAPPLHCHYGAFPPNASGWEQPPNASGVSVASAALAASAASRVATSTDPSCS 60
MASDPIFTLAPPLHCHYGAFPPNASGWEQPPNASGVSVASAALAASAASRVATSTDPSCS
Sbjct: 1 MASDPIFTLAPPLHCHYGAFPPNASGWEQPPNASGVSVASAALAASAASRVATSTDPSCS 60
Query: 61 GFAPPDFNHCLKDWDYNGLPVLTTNAIGQWDLVCDLGWQVILEQILFILGFASGYLFLGY 120
GFAPPDFNHCLKDWDYNGLPVLTTNAIGQWDLVCDLGWQVILEQILFILGFASGYLFLGY
Sbjct: 61 GFAPPDFNHCLKDWDYNGLPVLTTNAIGQWDLVCDLGWQVILEQILFILGFASGYLFLGY 120
Query: 121 PADRFGRRGIVLLTLGLVGPCGVGGAAAGSSTGVMALRFLLGFLLAGVDLGVYLMRLELC 180
PADRFGRRGIVLLTLGLVGPCGVGGAAAGSSTGVMALRFLLGFLLAGVDLGVYLMRLELC
Sbjct: 121 PADRFGRRGIVLLTLGLVGPCGVGGAAAGSSTGVMALRFLLGFLLAGVDLGVYLMRLELC 180
Query: 181 DPTQRLRVALAGELVGVGGHFLFLGLALVSKDWRFLQRMITAPCILFLFYGWPGLFLESA 240
DPTQRLRVALAGELVGVGGHFLFLGLALVSKDWRFLQRMITAPCILFLFYGWPGLFLESA
Sbjct: 181 DPTQRLRVALAGELVGVGGHFLFLGLALVSKDWRFLQRMITAPCILFLFYGWPGLFLESA 240
Query: 241 RWLIVKRQIEEAQSVLRILAERNRPHGQMLGEEAQEALQDLENTCPLPATSSFSFASLLN 300
RWLIVKRQIEEAQSVLRILAERNRPHGQMLGEEAQEALQDLENTCPLPATSSFSFASLLN
Sbjct: 241 RWLIVKRQIEEAQSVLRILAERNRPHGQMLGEEAQEALQDLENTCPLPATSSFSFASLLN 300
Query: 301 YRNIWKNLLILGFTNFIAHAIRHCYQPVGGGGSPSDFYLCSLLASGTAALACVFLGVTVD 360
YRNIWKNLLILGFTNFIAHAIRHCYQPVGGGGSPSDFYLCSLLASGTAALACVFLGVTVD
Sbjct: 301 YRNIWKNLLILGFTNFIAHAIRHCYQPVGGGGSPSDFYLCSLLASGTAALACVFLGVTVD 360
Query: 361 RFGRRGILLLSMTLTGIASLVLLGLWDY------------------LNEAAITTFSVLGL 402
RFGRRGILLLSMTLTGIASLVLLGLWD LNEAAITTFSVLGL
Sbjct: 361 RFGRRGILLLSMTLTGIASLVLLGLWDCEHPIFPTVWAQQGNPNRDLNEAAITTFSVLGL 420
Query: 403 FSSQAAAILSTLLAAEVIPTTVRGRGLGLIMALGALGGLSGPAQRLHMGHGAFLQHVVLA 462
FSSQAAAILSTLLAAEVIPTTVRGRGLGLIMALGALGGLSGPAQRLHMGHGAFLQHVVLA
Sbjct: 421 FSSQAAAILSTLLAAEVIPTTVRGRGLGLIMALGALGGLSGPAQRLHMGHGAFLQHVVLA 480
Query: 463 ACALLCILSIMLLPETKRKLLPEVLRDGELCRRPSLLRQPPPTRCDHVPLLATPNPAL 520
ACALLCILSIMLLPETKRKLLPEVLRDGELCRRPSLLRQPPPTRCDHVPLLATPNPAL
Sbjct: 481 ACALLCILSIMLLPETKRKLLPEVLRDGELCRRPSLLRQPPPTRCDHVPLLATPNPAL 538
>gi|239745643 PREDICTED: hypothetical protein LOC146429 isoform 1
[Homo sapiens]
Length = 558
Score = 283 bits (725), Expect = 2e-76
Identities = 180/432 (41%), Positives = 242/432 (56%), Gaps = 7/432 (1%)
Query: 90 WDLVCDLGWQVILEQILFILGFASGYLFLGYPADRFGRRGIVLLTLGLVGPCGVGGAAAG 149
W+LVC GW+V LEQ+ +LG+ G + LG DRFGRR + + +L L G A A
Sbjct: 119 WNLVCGDGWKVPLEQVSHLLGWLLGCVILGAGCDRFGRRAVFVASLVLTTGLGASEALAA 178
Query: 150 SSTGVMALRFLLGFLLAGVDLGVYLMRLELCDPTQRLRVALAGELVGVGGHFLFLGLALV 209
S ++ LR L G LAG L +YL RLELCDP RL ++ L V G L GLA +
Sbjct: 179 SFPTLLVLRLLHGGTLAGALLALYLARLELCDPPHRLAFSMGAGLFSVVGTLLLPGLAAL 238
Query: 210 SKDWRFLQRM-ITAPCILFLFYGWPGLFLESARWLIVKRQIEEAQSVLRILAERNR--PH 266
+DWR LQ + +L LF+G+P LF ES WL+ Q+ A+ +L AE + P
Sbjct: 239 VQDWRLLQGLGALMSGLLLLFWGFPALFPESPCWLLATGQVARARKILWRFAEASGVGPG 298
Query: 267 GQMLGEEAQEALQDLEN-TCPLPATSSFSFASLLNYRNIWKNLLILGFTNFIAHAIRHCY 325
L E + +L + P S LL R W+N LILGF++ + IR +
Sbjct: 299 DSSLEENSLATATELTMLSARSPQPRYHSPLGLLRTRVTWRNGLILGFSSLVGGGIRASF 358
Query: 326 QPVGGGGSPSDFYLCSLLASGTAALACVFLGVTVDRFGRRGILLLSMTLTGIASLVLLGL 385
+ P+ FYL L +G A A VFL +T D GRR +LLL +TG+ASL+LL
Sbjct: 359 RRSLAPQVPT-FYLPYFLEAGLEAAALVFLLLTADCCGRRPVLLLGTMVTGLASLLLLAG 417
Query: 386 WDYLNEAAITTFSVLGLFSSQAAAILSTLLAAEVIPTTVRGRGLGLIMALGALGGLSGPA 445
YL + SVLGL +S+A + LS+L AAEV PT +RG GLGL++ G LG +GP
Sbjct: 418 AQYLPGWTVLFLSVLGLLASRAVSALSSLFAAEVFPTVIRGAGLGLVLGAGFLGQAAGPL 477
Query: 446 QRLHMGHGAFLQHVVLAACALLCILSIMLLPETKRKLLPEVLRDGELCRRPSLLRQPPPT 505
LH G FLQ VV A+ A+L +L ++LLPE++ + LP+ L+D + RR LLR P
Sbjct: 478 DTLHGRQGFFLQQVVFASLAVLALLCVLLLPESRSRGLPQSLQDADRLRRSPLLRGRP-- 535
Query: 506 RCDHVPLLATPN 517
R DH+PLL N
Sbjct: 536 RQDHLPLLPPSN 547
>gi|239751156 PREDICTED: hypothetical protein LOC146429 isoform 6
[Homo sapiens]
Length = 560
Score = 280 bits (715), Expect = 3e-75
Identities = 179/432 (41%), Positives = 241/432 (55%), Gaps = 7/432 (1%)
Query: 90 WDLVCDLGWQVILEQILFILGFASGYLFLGYPADRFGRRGIVLLTLGLVGPCGVGGAAAG 149
W+LVC GW+V LEQ+ +LG+ G + LG DRFGRR + + +L L G A A
Sbjct: 121 WNLVCGDGWKVPLEQVSHLLGWLLGCVILGAGCDRFGRRAVFVASLVLTTGLGASEALAA 180
Query: 150 SSTGVMALRFLLGFLLAGVDLGVYLMRLELCDPTQRLRVALAGELVGVGGHFLFLGLALV 209
S ++ LR L G LAG L +YL RLELCDP RL ++ L V G L GLA +
Sbjct: 181 SFPTLLVLRLLHGGTLAGALLALYLARLELCDPPHRLAFSMGAGLFSVVGTLLLPGLAAL 240
Query: 210 SKDWRFLQRM-ITAPCILFLFYGWPGLFLESARWLIVKRQIEEAQSVLRILAERNR--PH 266
+DWR LQ + +L LF+G+P LF ES WL+ Q+ A+ +L AE + P
Sbjct: 241 VQDWRLLQGLGALMSGLLLLFWGFPALFPESPCWLLATGQVARARKILWRFAEASGVGPG 300
Query: 267 GQMLGEEAQEALQDLEN-TCPLPATSSFSFASLLNYRNIWKNLLILGFTNFIAHAIRHCY 325
L E + +L + P S LL R W+N LILGF++ + IR +
Sbjct: 301 DSSLEENSLATATELTMLSARSPQPRYHSPLGLLRTRVTWRNGLILGFSSLVGGGIRASF 360
Query: 326 QPVGGGGSPSDFYLCSLLASGTAALACVFLGVTVDRFGRRGILLLSMTLTGIASLVLLGL 385
+ P+ FYL L +G A A VFL +T D GRR +LLL +TG+ASL+LL
Sbjct: 361 RRSLAPQVPT-FYLPYFLEAGLEAAALVFLLLTADCCGRRPVLLLGTMVTGLASLLLLAG 419
Query: 386 WDYLNEAAITTFSVLGLFSSQAAAILSTLLAAEVIPTTVRGRGLGLIMALGALGGLSGPA 445
YL + SVLGL +S+A + LS+L AAEV PT +RG GLGL++ G LG +G
Sbjct: 420 AQYLPGWTVLFLSVLGLLASRAVSALSSLFAAEVFPTVIRGAGLGLVLGAGFLGQAAGLL 479
Query: 446 QRLHMGHGAFLQHVVLAACALLCILSIMLLPETKRKLLPEVLRDGELCRRPSLLRQPPPT 505
LH G FLQ VV A+ A+L +L ++LLPE++ + LP+ L+D + RR LLR P
Sbjct: 480 DTLHGRQGFFLQQVVFASLAVLALLCVLLLPESRSRGLPQSLQDADRLRRSPLLRGRP-- 537
Query: 506 RCDHVPLLATPN 517
R DH+PLL N
Sbjct: 538 RQDHLPLLPPSN 549
>gi|170650643 solute carrier family 22, member 23 isoform a [Homo
sapiens]
Length = 686
Score = 261 bits (666), Expect = 1e-69
Identities = 164/483 (33%), Positives = 245/483 (50%), Gaps = 45/483 (9%)
Query: 63 APPD-----FNHCLKDWDYNGLPVLTTNAIGQWDLVCDLGWQVILEQILFILGFASGYLF 117
+PPD N + WDY L N + +WDLVCD W+V + + ++G GYL
Sbjct: 187 SPPDKGDNASNCDCRAWDYGIRAGLVQNVVSKWDLVCDNAWKVHIAKFSLLVGLIFGYLI 246
Query: 118 LGYPADRFGRRGIVLLTLGLVGPCGVGGAAAGSSTGVMALRFLLGFLLAGVDLGVYLMRL 177
G AD GRR ++L ++ + G+ A + + T LRF GF LAG+ L +Y +R+
Sbjct: 247 TGCIADWVGRRPVLLFSIIFILIFGLTVALSVNVTMFSTLRFFEGFCLAGIILTLYALRI 306
Query: 178 ELCDPTQRLRVALAGELVGVGGHFLFLGLALVSKDWRFLQRMITAPCILFLFYGWPGLFL 237
ELC P +R + + V + G FL GLA + +DW+ LQ +I P +L L Y W +F
Sbjct: 307 ELCPPGKRFMITMVASFVAMAGQFLMPGLAALCRDWQVLQALIICPFLLMLLY-W-SIFP 364
Query: 238 ESARWLIVKRQIEEAQSVLRILAERNR--PHGQMLG---EEAQEALQDLENTCPLPATSS 292
ES RWL+ +Q E A+ ++ ++NR P G + G E +E + + C
Sbjct: 365 ESLRWLMATQQFESAKRLILHFTQKNRMNPEGDIKGVIPELEKELSRRPKKVC------- 417
Query: 293 FSFASLLNYRNIWKNLLILGFTNFIAHAIRHCYQPVGGGGSP-----SDFYLCSLLASGT 347
++ RN+WKN+++L + + I HC+ G +FY +
Sbjct: 418 --IVKVVGTRNLWKNIVVLCVNSLTGYGIHHCFARSMMGHEVKVPLLENFYADYYTTASI 475
Query: 348 AALACVFLGVTVDRFGRRGILLLSMTLTGIASLVLLGLW---------------DYLNEA 392
A ++C+ + V V GRRG LLL M LT +ASL+ LGL D + +
Sbjct: 476 ALVSCLAMCVVVRFLGRRGGLLLFMILTALASLLQLGLLNLIGKYSQHPDSGMSDSVKDK 535
Query: 393 AITTFSVLGLFSSQAAAILSTLLAAEVIPTTVRGRGLGLIMALGALGGLSGPAQRLHMGH 452
FS++G+F+S A LS AE+ PT +R GLGL++A G L+ P LH
Sbjct: 536 FSIAFSIVGMFASHAVGSLSVFFCAEITPTVIRCGGLGLVLASAGFGMLTAPIIELHNQK 595
Query: 453 GAFLQHVVLAACALLCILSIMLLPETKRKLLPEVLRDGELCRRPSLLRQPPPTRCDHVPL 512
G FL H++ A C L+CI+ I+LLPE++ + LPE + +GE R LL P + PL
Sbjct: 596 GYFLHHIIFACCTLICIICILLLPESRDQNLPENISNGEHYTRQPLL----PHKKGEQPL 651
Query: 513 LAT 515
L T
Sbjct: 652 LLT 654
>gi|48526516 solute carrier family 22, member 23 isoform b [Homo
sapiens]
Length = 405
Score = 213 bits (541), Expect = 4e-55
Identities = 133/384 (34%), Positives = 197/384 (51%), Gaps = 40/384 (10%)
Query: 157 LRFLLGFLLAGVDLGVYLMRLELCDPTQRLRVALAGELVGVGGHFLFLGLALVSKDWRFL 216
LRF GF LAG+ L +Y +R+ELC P +R + + V + G FL GLA + +DW+ L
Sbjct: 5 LRFFEGFCLAGIILTLYALRIELCPPGKRFMITMVASFVAMAGQFLMPGLAALCRDWQVL 64
Query: 217 QRMITAPCILFLFYGWPGLFLESARWLIVKRQIEEAQSVLRILAERNR--PHGQMLG--- 271
Q +I P +L L Y W +F ES RWL+ +Q E A+ ++ ++NR P G + G
Sbjct: 65 QALIICPFLLMLLY-W-SIFPESLRWLMATQQFESAKRLILHFTQKNRMNPEGDIKGVIP 122
Query: 272 EEAQEALQDLENTCPLPATSSFSFASLLNYRNIWKNLLILGFTNFIAHAIRHCYQPVGGG 331
E +E + + C ++ RN+WKN+++L + + I HC+ G
Sbjct: 123 ELEKELSRRPKKVC---------IVKVVGTRNLWKNIVVLCVNSLTGYGIHHCFARSMMG 173
Query: 332 GSPS-----DFYLCSLLASGTAALACVFLGVTVDRFGRRGILLLSMTLTGIASLVLLGLW 386
+FY + A ++C+ + V V GRRG LLL M LT +ASL+ LGL
Sbjct: 174 HEVKVPLLENFYADYYTTASIALVSCLAMCVVVRFLGRRGGLLLFMILTALASLLQLGLL 233
Query: 387 ---------------DYLNEAAITTFSVLGLFSSQAAAILSTLLAAEVIPTTVRGRGLGL 431
D + + FS++G+F+S A LS AE+ PT +R GLGL
Sbjct: 234 NLIGKYSQHPDSGMSDSVKDKFSIAFSIVGMFASHAVGSLSVFFCAEITPTVIRCGGLGL 293
Query: 432 IMALGALGGLSGPAQRLHMGHGAFLQHVVLAACALLCILSIMLLPETKRKLLPEVLRDGE 491
++A G L+ P LH G FL H++ A C L+CI+ I+LLPE++ + LPE + +GE
Sbjct: 294 VLASAGFGMLTAPIIELHNQKGYFLHHIIFACCTLICIICILLLPESRDQNLPENISNGE 353
Query: 492 LCRRPSLLRQPPPTRCDHVPLLAT 515
R LL P + PLL T
Sbjct: 354 HYTRQPLL----PHKKGEQPLLLT 373
>gi|239756672 PREDICTED: hypothetical protein LOC146429 [Homo
sapiens]
Length = 495
Score = 194 bits (494), Expect = 1e-49
Identities = 149/432 (34%), Positives = 204/432 (47%), Gaps = 70/432 (16%)
Query: 90 WDLVCDLGWQVILEQILFILGFASGYLFLGYPADRFGRRGIVLLTLGLVGPCGVGGAAAG 149
W+LVC GW+V LEQ+ +LG+ G + LG DRFGRR + + +L L G A A
Sbjct: 119 WNLVCGDGWKVPLEQVSHLLGWLLGCVILGAGCDRFGRRAVFVASLVLTTGLGASEALAA 178
Query: 150 SSTGVMALRFLLGFLLAGVDLGVYLMRLELCDPTQRLRVALAGELVGVGGHFLFLGLALV 209
S ++ LR L G LAG L +YL RLELCDP RL ++ L V G L GLA +
Sbjct: 179 SFPTLLVLRLLHGGTLAGALLALYLARLELCDPPHRLAFSMGAGLFSVVGTLLLPGLAAL 238
Query: 210 SKDWRFLQRM-ITAPCILFLFYGWPGLFLESARWLIVKRQIEEAQSVLRILAERN--RPH 266
+DWR LQ + +L LF+G+P LF ES WL+ Q+ A+ +L AE + P
Sbjct: 239 VQDWRLLQGLGALMSGLLLLFWGFPALFPESPCWLLATGQVARARKILWRFAEASGVGPG 298
Query: 267 GQMLGEEAQEALQDLEN-TCPLPATSSFSFASLLNYRNIWKNLLILGFTNFIAHAIRHCY 325
L E + +L + P S LL R W+N LILGF++
Sbjct: 299 DSSLEENSLATATELTMLSARSPQPRYHSPLGLLRTRVTWRNGLILGFSSL--------- 349
Query: 326 QPVGGGGSPSDFYLCSLLASGTAALACVFLGVTVDRFGRRGILLLSMTLTGIASLVLLGL 385
VGGG + + +FL V LGL
Sbjct: 350 --VGGG-----------IRANLPGWTVLFLSV-------------------------LGL 371
Query: 386 WDYLNEAAITTFSVLGLFSSQAAAILSTLLAAEVIPTTVRGRGLGLIMALGALGGLSGPA 445
+ + +V L S AA + T+ +RG GLGL++ G LG +G
Sbjct: 372 --------LASRAVSALSSLFAAEVFPTV---------IRGAGLGLVLGAGFLGQAAGLL 414
Query: 446 QRLHMGHGAFLQHVVLAACALLCILSIMLLPETKRKLLPEVLRDGELCRRPSLLRQPPPT 505
LH G FLQ VV A+ A+L +L ++LLPE++ + LP+ L+D + RR LLR P
Sbjct: 415 DTLHGRQGFFLQQVVFASLAVLALLCVLLLPESRSRGLPQSLQDADRLRRSPLLRGRP-- 472
Query: 506 RCDHVPLLATPN 517
R DH+PLL N
Sbjct: 473 RQDHLPLLPPSN 484
>gi|11415038 solute carrier family 22 member 3 [Homo sapiens]
Length = 556
Score = 143 bits (360), Expect = 4e-34
Identities = 142/466 (30%), Positives = 208/466 (44%), Gaps = 37/466 (7%)
Query: 39 ASAALAASAASRVATSTDPSCSGFAPPDFNHCLKDWDYNGLPVLTTNAIGQWDLVCDLGW 98
ASA A S A +A P+ S P C W Y + + ++DLVC W
Sbjct: 102 ASATSALSCADPLAAF--PNRSAPLVP----CRGGWRY---AQAHSTIVSEFDLVCVNAW 152
Query: 99 QVILEQILFILGFASGYLFLGYPADRFGRRGIVLLTLGLVGPCGVGGAAAGSSTGVMALR 158
+ L Q + LGF +G LGY ADR+GR I LL+ VG GV A A + + R
Sbjct: 153 MLDLTQAILNLGFLTGAFTLGYAADRYGRIVIYLLSCLGVGVTGVVVAFAPNFPVFVIFR 212
Query: 159 FLLGFLLAGVDLGVYLMRLELCDPTQRLRVALAGELVGVGGHFLFLGLALVSKDWRFLQR 218
FL G G + Y++ E+ QR V + ++ G + G+A +W+ +Q
Sbjct: 213 FLQGVFGKGTWMTCYVIVTEIVGSKQRRIVGIVIQMFFTLGIIILPGIAYFIPNWQGIQL 272
Query: 219 MITAPCILFLFYGWPGLFLESARWLIVKRQIEEAQSVLRILAERNRPHGQMLGEEAQEAL 278
IT P LFL Y W + ES RWLI +++ ++A +LR +A+ N G+ L E
Sbjct: 273 AITLPSFLFLLYYW--VVPESPRWLITRKKGDKALQILRRIAKCN---GKYLSSNYSEI- 326
Query: 279 QDLENTCPLPATSSFSFASLLNYRNIWKNLLILGFTNFIAHAIRHCYQ------PVGGGG 332
T S+ SF L+ + K LIL F F + + YQ + GG
Sbjct: 327 -----TVTDEEVSNPSFLDLVRTPQMRKCTLILMFAWFTSAVV---YQGLVMRLGIIGGN 378
Query: 333 SPSDFYLCSLLASGTAAL-ACVFLGVTVDRFGRRGILLLSMTLTGIASLVLLGLWDYLNE 391
DF++ SG L + + +T++R GRR S + G+A LV L + +
Sbjct: 379 LYIDFFI-----SGVVELPGALLILLTIERLGRRLPFAASNIVAGVACLVTAFLPEGIAW 433
Query: 392 AAITTFSVLGLFSSQAAAILSTLLAAEVIPTTVRGRGLGLIMALGALGGLSGPAQRLHMG 451
TT + LG A + L+ +E+ PTT+R G+ L L GG+ P +
Sbjct: 434 LR-TTVATLGRLGITMAFEIVYLVNSELYPTTLRNFGVSLCSGLCDFGGIIAPFLLFRLA 492
Query: 452 H-GAFLQHVVLAACALLCILSIMLLPETKRKLLPEVLRDGELCRRP 496
L ++ A +C +MLLPETK LPE + D E P
Sbjct: 493 AVWLELPLIIFGILASICGGLVMLLPETKGIALPETVDDVEKLGSP 538
>gi|166064021 solute carrier family 22 (organic anion transporter),
member 13 [Homo sapiens]
Length = 551
Score = 135 bits (340), Expect = 9e-32
Identities = 133/482 (27%), Positives = 210/482 (43%), Gaps = 35/482 (7%)
Query: 39 ASAALAASAASRVATSTDPSCSGFAPPDFNHCLKD---------------WDY--NGLPV 81
A+ L S A +P C F PP N L+D W+Y N LP
Sbjct: 64 AAEQLVLSVPLDTAGHPEP-CLMFRPPPANASLQDILSHRFNETQPCDMGWEYPENRLPS 122
Query: 82 LTTNAIGQWDLVCDLGWQVILEQILFILGFASGYLFLGYPADRFGRRGIVLLTLGLVGPC 141
L +++LVCD Q +F+ G G L G DR GR+ +L L L
Sbjct: 123 LKN----EFNLVCDRKHLKDTTQSVFMAGLLVGTLMFGPLCDRIGRKATILAQLLLFTLI 178
Query: 142 GVGGAAAGSSTGVMALRFLLGFLLAGVDLGVYLMRLELCDPTQRLRVALAGELVGVGGHF 201
G+ A S MALRF + +AG+ + E P+ R + + + G
Sbjct: 179 GLATAFVPSFELYMALRFAVATAVAGLSFSNVTLLTEWVGPSWRTQAVVLAQCNFSLGQM 238
Query: 202 LFLGLALVSKDWRFLQRMITAPCILFLFYGWPGLFLESARWLIVKRQIEEAQSVLRILAE 261
+ GLA ++WR LQ TAP +L FY W ESARWL+ + +++EA +++ A
Sbjct: 239 VLAGLAYGFRNWRLLQITGTAPGLLLFFYFW--ALPESARWLLTRGRMDEAIQLIQKAAS 296
Query: 262 RNRPHGQMLGEEAQEALQDLENTCPLPATSSFSFASLLNYRNIWKNLLILGFTNFIAHAI 321
NR + L E L E T P S + L + + K LI+ F + ++
Sbjct: 297 VNR---RKLSPELMNQLVP-EKTGP-----SGNALDLFRHPQLRKVTLII-FCVWFVDSL 346
Query: 322 RHCYQPVGGGGSPSDFYLCSLLASGTAALACVFLGVTVDRFGRRGILLLSMTLTGIASLV 381
+ + G D YL L+ A + RFGR+ L ++ L G+ ++
Sbjct: 347 GYYGLSLQVGDFGLDVYLTQLIFGAVEVPARCSSIFMMQRFGRKWSQLGTLVLGGLMCII 406
Query: 382 LLGLWDYLNEAAITTFSVLGLFSSQAAAILSTLLAAEVIPTTVRGRGLGLIMALGALGGL 441
++ + L +T +V+G ++ AA +S + +AE+ PT +R G+GL+ +GG+
Sbjct: 407 IIFIPADL-PVVVTMLAVVGKMATAAAFTISYVYSAELFPTILRQTGMGLVGIFSRIGGI 465
Query: 442 SGPAQRLHMGHGAFLQHVVLAACALLCILSIMLLPETKRKLLPEVLRDGELCRRPSLLRQ 501
P L + A L ++ + ++ L LLPET + L + L+D EL P +
Sbjct: 466 LTPLVILLGEYHAALPMLIYGSLPIVAGLLCTLLPETHGQGLKDTLQDLELGPHPRSPKS 525
Query: 502 PP 503
P
Sbjct: 526 VP 527
>gi|4506999 solute carrier family 22 member 1 isoform a [Homo
sapiens]
Length = 554
Score = 125 bits (315), Expect = 7e-29
Identities = 123/427 (28%), Positives = 192/427 (44%), Gaps = 23/427 (5%)
Query: 70 CLKDWDYNGLPVLTTNAIGQWDLVCDLGWQVILEQILFILGFASGYLFLGYPADRFGRRG 129
C W Y+ ++ + +++LVC W++ L Q GF G L +GY ADRFGR+
Sbjct: 121 CQDGWVYD---TPGSSIVTEFNLVCADSWKLDLFQSCLNAGFLFGSLGVGYFADRFGRKL 177
Query: 130 IVLLTLGLVGPCGVGGAAAGSSTGVMALRFLLGFLLAGVDLGVYLMRLELCDPTQRLRVA 189
+L T+ + GV A + + ++ R L G + G + Y + E R VA
Sbjct: 178 CLLGTVLVNAVSGVLMAFSPNYMSMLLFRLLQGLVSKGNWMAGYTLITEFVGSGSRRTVA 237
Query: 190 LAGELVGVGGHFLFLGLALVSKDWRFLQRMITAPCILFLFYGWPGLFLESARWLIVKRQI 249
+ ++ G GLA WR+LQ ++ P LFL Y W ES RWL+ +++
Sbjct: 238 IMYQMAFTVGLVALTGLAYALPHWRWLQLAVSLPTFLFLLYYW--CVPESPRWLLSQKRN 295
Query: 250 EEAQSVLRILAERNRPHGQMLGEEAQEALQDLENTCPLPATSSFSFASLLNYRNIWKN-- 307
EA ++ +A++N G+ L+ L + S SFA L + K
Sbjct: 296 TEAIKIMDHIAQKN-------GKLPPADLKMLSLEEDVTEKLSPSFADLFRTPRLRKRTF 348
Query: 308 -LLILGFTNFIAHAIRHCYQPVGGGGSPSDFYLCSLLASGTAALACVFLGVTVDRFGRRG 366
L+ L FT+ + + + G DF +L+ A +A +T+DR GR
Sbjct: 349 ILMYLWFTDSVLYQGLILHMGATSGNLYLDFLYSALVEIPGAFIAL----ITIDRVGRIY 404
Query: 367 ILLLSMTLTGIASLVLLGLWDYLNEAAITTFSVLGLFSSQAAAILSTLLAAEVIPTTVRG 426
+ +S L G A LV++ + L+ I V G A + L+ AE+ PT VR
Sbjct: 405 PMAMSNLLAGAACLVMIFISPDLHWLNIIIMCV-GRMGITIAIQMICLVNAELYPTFVRN 463
Query: 427 RGLGLIMALGALGGLSGP--AQRLHMGHGAFLQHVVLAACALLCILSIMLLPETKRKLLP 484
G+ + +L +GG+ P RL A L ++ A LL +LLPETK LP
Sbjct: 464 LGVMVCSSLCDIGGIITPFIVFRLREVWQA-LPLILFAVLGLLAAGVTLLLPETKGVALP 522
Query: 485 EVLRDGE 491
E ++D E
Sbjct: 523 ETMKDAE 529
>gi|24497499 solute carrier family 22 member 8 [Homo sapiens]
Length = 542
Score = 125 bits (315), Expect = 7e-29
Identities = 125/491 (25%), Positives = 205/491 (41%), Gaps = 26/491 (5%)
Query: 6 IFTLAPPLHCHYGAFPPNASG--WEQPPNASGVSVASAALAASAASRVATSTDPSCSGFA 63
IFT A P+H + P NAS W P +G + + T +
Sbjct: 39 IFTAATPVH--HCRPPHNASTGPWVLPMGPNGKPERCLRFVHPPNASLPNDTQRA----- 91
Query: 64 PPDFNHCLKDWDYNGLPVLTTNAIGQWDLVCDLGWQVILEQILFILGFASGYLFLGYPAD 123
CL W YN + + +WDLVC+ + Q +F+ G G L LG +D
Sbjct: 92 ---MEPCLDGWVYNSTK---DSIVTEWDLVCNSNKLKEMAQSIFMAGILIGGLVLGDLSD 145
Query: 124 RFGRRGIVLLTLGLVGPCGVGGAAAGSSTGVMALRFLLGFLLAGVDLGVYLMRLELCDPT 183
RFGRR I+ + L+ G G A + + M RFL GF ++G+ L ++ +E
Sbjct: 146 RFGRRPILTCSYLLLAASGSGAAFSPTFPIYMVFRFLCGFGISGITLSTVILNVEWVPTR 205
Query: 184 QRLRVALAGELVGVGGHFLFLGLALVSKDWRFLQRMITAPCILFLFYGWPGLFLESARWL 243
R ++ A G F+ GLA WR+LQ ++ P +F W ES RWL
Sbjct: 206 MRAIMSTALGYCYTFGQFILPGLAYAIPQWRWLQLTVSIPFFVFFLSSW--WTPESIRWL 263
Query: 244 IVKRQIEEAQSVLRILAERN--RPHGQMLG-EEAQEALQDLENTCPLPATSSFSFASLLN 300
++ + +A +LR +A N + G+ L EE + LQ + T+S F +
Sbjct: 264 VLSGKSSKALKILRRVAVFNGKKEEGERLSLEELKLNLQKEISLAKAKYTASDLFRIPML 323
Query: 301 YRNIWKNLLILGFTNFIAHAIRHCYQPVGGGGSPSDFYLCSLLASGTAALACVFLGVTVD 360
R + L T F +++ + G + Y+ ++ G A +++
Sbjct: 324 RRMTFCLSLAWFATGFAYYSLAMGVEEFG-----VNLYILQIIFGGVDVPAKFITILSLS 378
Query: 361 RFGRRGILLLSMTLTGIASLVLLGLWDYLNEAAITTFSVLGLFSSQAAAILSTLLAAEVI 420
GR ++ L G A L L + L + T +V G ++ L +E+
Sbjct: 379 YLGRHTTQAAALLLAGGAILALTFVPLDL-QTVRTVLAVFGKGCLSSSFSCLFLYTSELY 437
Query: 421 PTTVRGRGLGLIMALGALGGLSGPAQRLHMGHGAFLQHVVLAACALLCILSIMLLPETKR 480
PT +R G+G+ +G + P ++ F+ +++ ALL + + LPET
Sbjct: 438 PTVIRQTGMGVSNLWTRVGSMVSPLVKITGEVQPFIPNIIYGITALLGGSAALFLPETLN 497
Query: 481 KLLPEVLRDGE 491
+ LPE + D E
Sbjct: 498 QPLPETIEDLE 508
>gi|90669191 solute carrier family 22 member 7 isoform b [Homo
sapiens]
Length = 548
Score = 125 bits (314), Expect = 9e-29
Identities = 122/442 (27%), Positives = 192/442 (43%), Gaps = 26/442 (5%)
Query: 70 CLKDWDYNGLPVLTTNAI-GQWDLVCDLGWQVILEQILFILGFASGYLFLGYPADRFGRR 128
C + W+Y+ +T A QWDLVC+ F G G + GY +DRFGRR
Sbjct: 113 CSQGWEYDHSEFSSTIATESQWDLVCEQKGLNRAASTFFFAGVLVGAVAFGYLSDRFGRR 172
Query: 129 GIVLLTLGLVGPCGVGGAAAGSSTGVMALRFLLGFLLAGVDLGVYLMRLELCDPTQRLRV 188
++L+ G+ AA+ S R L G LAG + V + LE D R
Sbjct: 173 RLLLVAYVSTLVLGLASAASVSYVMFAITRTLTGSALAGFTIIVMPLELEWLDVEHRTVA 232
Query: 189 ALAGELVGVGGHFLFLGLALVSKDWRFLQRMITAPCILFLFYGWPGLFLESARWLIVKRQ 248
+ GG L + + +DWR+L +T PC + W ESARWL+ +
Sbjct: 233 GVLSSTFWTGGVMLLALVGYLIRDWRWLLLAVTLPCAPGILSLW--WVPESARWLLTQGH 290
Query: 249 IEEAQSVLRILAERNRPHGQMLGEE--AQEALQDL---ENTCPLPATSSFSFASLLNYRN 303
++EA R L R +G+ + E+ +QEA+ + E P+ L + +
Sbjct: 291 VKEAH---RYLLHCARLNGRPVCEDSFSQEAVSKVAAGERVVRRPSYLDLFRTPRLRHIS 347
Query: 304 IWKNLLILGFTNFIAHAIRHCYQPVGGGGSPSDFYLCSLLASGTAALACVFLGVTVDRFG 363
+ ++ G NF + + + G + Y LL + + + ++V G
Sbjct: 348 LCCVVVWFG-VNFSYYGL-----SLDVSGLGLNVYQTQLLFGAVELPSKLLVYLSVRYAG 401
Query: 364 RR----GILLLSMTLTGIASLVLLGLWDYLNEAAITTFSVLGLFSSQAAAILSTLLAAEV 419
RR G LL + G LV + ++ T +V+G S+AA + L +E+
Sbjct: 402 RRLTQAGTLLGTALAFGTRLLVSSDM-----KSWSTVLAVMGKAFSEAAFTTAYLFTSEL 456
Query: 420 IPTTVRGRGLGLIMALGALGGLSGPAQRLHMGHGAFLQHVVLAACALLCILSIMLLPETK 479
PT +R G+GL +G LGG P L G L + ALL + +LLPET+
Sbjct: 457 YPTVLRQTGMGLTALVGRLGGSLAPLAALLDGVWLSLPKLTYGGIALLAAGTALLLPETR 516
Query: 480 RKLLPEVLRDGELCRRPSLLRQ 501
+ LPE ++D E P+ L++
Sbjct: 517 QAQLPETIQDVERKSAPTSLQE 538
>gi|24497476 solute carrier family 22 member 6 isoform b [Homo
sapiens]
Length = 550
Score = 125 bits (313), Expect = 1e-28
Identities = 124/456 (27%), Positives = 192/456 (42%), Gaps = 27/456 (5%)
Query: 70 CLKDWDYNGLPVLTTNAIGQWDLVCDLGWQVILEQILFILGFASGYLFLGYPADRFGRRG 129
C W Y+ +T + +WDLVC L Q L+++G G + GY ADR GRR
Sbjct: 105 CTDGWIYDNSTFPST-IVTEWDLVCSHRALRQLAQSLYMVGVLLGAMVFGYLADRLGRRK 163
Query: 130 IVLLTLGLVGPCGVGGAAAGSSTGVMALRFLLGFLLAGVDLGVYLMRLELCDPTQRLRVA 189
+++L G A A + A R L G LAG+ L + +E R A
Sbjct: 164 VLILNYLQTAVSGTCAAFAPNFPIYCAFRLLSGMALAGISLNCMTLNVEWMPIHTR---A 220
Query: 190 LAGELVGVG---GHFLFLGLALVSKDWRFLQRMITAPCILFLFYGWPGLFLESARWLIVK 246
G L+G G FL G+A WR LQ +++AP F Y W F+ESARW
Sbjct: 221 CVGTLIGYVYSLGQFLLAGVAYAVPHWRHLQLLVSAPFFAFFIYSW--FFIESARWHSSS 278
Query: 247 RQIEEAQSVLRILAERN--RPHGQMLGEEAQEALQDLENTCPLPATSSFSFASLLNYRNI 304
+++ L+ +A N R G L E A E T S+ R++
Sbjct: 279 GRLDLTLRALQRVARINGKREEGAKLSMEVLRASLQKELTMGKGQASAMELLRCPTLRHL 338
Query: 305 WKNLLILGF-TNFIAHAIRHCYQPVGGGGSPSDFYLCSLLASGTAALACVFLGVTVDRFG 363
+ L +L F T+F + + Q G YL ++ A + + ++ G
Sbjct: 339 FLCLSMLWFATSFAYYGLVMDLQGFG-----VSIYLIQVIFGAVDLPAKLVGFLVINSLG 393
Query: 364 RRGILLLSMTLTGIASLVLLGLWDYLNEAAITTFSVLGLFSSQAAAILSTLLAAEVIPTT 423
RR + ++ L GI ++L G+ T+ +VLG A+ L E+ PT
Sbjct: 394 RRPAQMAALLLAGIC-ILLNGVIPQDQSIVRTSLAVLGKGCLAASFNCIFLYTGELYPTM 452
Query: 424 VRGRGLGLIMALGALGGLSGP----AQRLHMGHGAFLQHVVLAACALLCILSIMLLPETK 479
+R G+G+ + +G + P L+ F+ V A + + + LLPET
Sbjct: 453 IRQTGMGMGSTMARVGSIVSPLVSMTAELYPSMPLFIYGAVPVAASAVTV----LLPETL 508
Query: 480 RKLLPEVLRDGELCRRPSLLRQPPPTRCDHVPLLAT 515
+ LP+ ++D E R+ RQ + VPL A+
Sbjct: 509 GQPLPDTVQDLE-SRKGKQTRQQQEHQKYMVPLQAS 543
>gi|24497497 solute carrier family 22 member 7 isoform a [Homo
sapiens]
Length = 546
Score = 124 bits (311), Expect = 2e-28
Identities = 121/441 (27%), Positives = 192/441 (43%), Gaps = 26/441 (5%)
Query: 70 CLKDWDYNGLPVLTTNAIGQWDLVCDLGWQVILEQILFILGFASGYLFLGYPADRFGRRG 129
C + W+Y+ +T A +WDLVC+ F G G + GY +DRFGRR
Sbjct: 113 CSQGWEYDHSEFSSTIAT-EWDLVCEQKGLNRAASTFFFAGVLVGAVAFGYLSDRFGRRR 171
Query: 130 IVLLTLGLVGPCGVGGAAAGSSTGVMALRFLLGFLLAGVDLGVYLMRLELCDPTQRLRVA 189
++L+ G+ AA+ S R L G LAG + V + LE D R
Sbjct: 172 LLLVAYVSTLVLGLASAASVSYVMFAITRTLTGSALAGFTIIVMPLELEWLDVEHRTVAG 231
Query: 190 LAGELVGVGGHFLFLGLALVSKDWRFLQRMITAPCILFLFYGWPGLFLESARWLIVKRQI 249
+ GG L + + +DWR+L +T PC + W ESARWL+ + +
Sbjct: 232 VLSSTFWTGGVMLLALVGYLIRDWRWLLLAVTLPCAPGILSLW--WVPESARWLLTQGHV 289
Query: 250 EEAQSVLRILAERNRPHGQMLGEE--AQEALQDL---ENTCPLPATSSFSFASLLNYRNI 304
+EA R L R +G+ + E+ +QEA+ + E P+ L + ++
Sbjct: 290 KEAH---RYLLHCARLNGRPVCEDSFSQEAVSKVAAGERVVRRPSYLDLFRTPRLRHISL 346
Query: 305 WKNLLILGFTNFIAHAIRHCYQPVGGGGSPSDFYLCSLLASGTAALACVFLGVTVDRFGR 364
++ G NF + + + G + Y LL + + + ++V GR
Sbjct: 347 CCVVVWFG-VNFSYYGL-----SLDVSGLGLNVYQTQLLFGAVELPSKLLVYLSVRYAGR 400
Query: 365 R----GILLLSMTLTGIASLVLLGLWDYLNEAAITTFSVLGLFSSQAAAILSTLLAAEVI 420
R G LL + G LV + ++ T +V+G S+AA + L +E+
Sbjct: 401 RLTQAGTLLGTALAFGTRLLVSSDM-----KSWSTVLAVMGKAFSEAAFTTAYLFTSELY 455
Query: 421 PTTVRGRGLGLIMALGALGGLSGPAQRLHMGHGAFLQHVVLAACALLCILSIMLLPETKR 480
PT +R G+GL +G LGG P L G L + ALL + +LLPET++
Sbjct: 456 PTVLRQTGMGLTALVGRLGGSLAPLAALLDGVWLSLPKLTYGGIALLAAGTALLLPETRQ 515
Query: 481 KLLPEVLRDGELCRRPSLLRQ 501
LPE ++D E P+ L++
Sbjct: 516 AQLPETIQDVERKSAPTSLQE 536
>gi|4507001 solute carrier family 22 member 2 [Homo sapiens]
Length = 555
Score = 124 bits (310), Expect = 3e-28
Identities = 115/431 (26%), Positives = 192/431 (44%), Gaps = 21/431 (4%)
Query: 70 CLKDWDYNGLPVLTTNAIGQWDLVCDLGWQVILEQILFILGFASGYLFLGYPADRFGRRG 129
C W Y ++ + +++LVC W + L Q +GF G + +GY ADRFGR+
Sbjct: 122 CRDGWVYE---TPGSSIVTEFNLVCANSWMLDLFQSSVNVGFFIGSMSIGYIADRFGRKL 178
Query: 130 IVLLTLGLVGPCGVGGAAAGSSTGVMALRFLLGFLLAGVDLGVYLMRLELCDPTQRLRVA 189
+L T+ + GV A + + T ++ R + G + L Y++ E R V
Sbjct: 179 CLLTTVLINAAAGVLMAISPTYTWMLIFRLIQGLVSKAGWLIGYILITEFVGRRYRRTVG 238
Query: 190 LAGELVGVGGHFLFLGLALVSKDWRFLQRMITAPCILFLFYGWPGLFLESARWLIVKRQI 249
+ ++ G + G+A WR+LQ + P FL Y W ES RWLI + +
Sbjct: 239 IFYQVAYTVGLLVLAGVAYALPHWRWLQFTVALPNFFFLLYYW--CIPESPRWLISQNKN 296
Query: 250 EEAQSVLRILAERNRPHGQMLGEEAQEALQDLENTCPLPATSSFSFASLLNYRNIWKNLL 309
EA +++ +A++N G+ +LQ L + SF L+ I K+ +
Sbjct: 297 AEAMRIIKHIAKKN-------GKSLPASLQRLRLEEETGKKLNPSFLDLVRTPQIRKHTM 349
Query: 310 IL---GFTNFIAHAIRHCYQPVGGGGSPSDFYLCSLLASGTAALACVFLGVTVDRFGRRG 366
IL FT+ + + + + G DF+ +L+ A + + +T+DR GRR
Sbjct: 350 ILMYNWFTSSVLYQGLIMHMGLAGDNIYLDFFYSALVEFPAAFM----IILTIDRIGRRY 405
Query: 367 ILLLSMTLTGIASLVLLGLWDYLNEAAITTFSVLGLFSSQAAAILSTLLAAEVIPTTVRG 426
S + G A L + + L I S LG A + L+ AE+ PT +R
Sbjct: 406 PWAASNMVAGAACLASVFIPGDLQWLKI-IISCLGRMGITMAYEIVCLVNAELYPTFIRN 464
Query: 427 RGLGLIMALGALGGLSGPAQRLHMGH-GAFLQHVVLAACALLCILSIMLLPETKRKLLPE 485
G+ + ++ +GG+ P + + L +V L+ ++LLPETK K LPE
Sbjct: 465 LGVHICSSMCDIGGIITPFLVYRLTNIWLELPLMVFGVLGLVAGGLVLLLPETKGKALPE 524
Query: 486 VLRDGELCRRP 496
+ + E +RP
Sbjct: 525 TIEEAENMQRP 535
>gi|20070188 solute carrier family 22 member 6 isoform a [Homo
sapiens]
Length = 563
Score = 123 bits (308), Expect = 5e-28
Identities = 117/432 (27%), Positives = 182/432 (42%), Gaps = 26/432 (6%)
Query: 70 CLKDWDYNGLPVLTTNAIGQWDLVCDLGWQVILEQILFILGFASGYLFLGYPADRFGRRG 129
C W Y+ +T + +WDLVC L Q L+++G G + GY ADR GRR
Sbjct: 105 CTDGWIYDNSTFPST-IVTEWDLVCSHRALRQLAQSLYMVGVLLGAMVFGYLADRLGRRK 163
Query: 130 IVLLTLGLVGPCGVGGAAAGSSTGVMALRFLLGFLLAGVDLGVYLMRLELCDPTQRLRVA 189
+++L G A A + A R L G LAG+ L + +E R A
Sbjct: 164 VLILNYLQTAVSGTCAAFAPNFPIYCAFRLLSGMALAGISLNCMTLNVEWMPIHTR---A 220
Query: 190 LAGELVGVG---GHFLFLGLALVSKDWRFLQRMITAPCILFLFYGWPGLFLESARWLIVK 246
G L+G G FL G+A WR LQ +++AP F Y W F+ESARW
Sbjct: 221 CVGTLIGYVYSLGQFLLAGVAYAVPHWRHLQLLVSAPFFAFFIYSW--FFIESARWHSSS 278
Query: 247 RQIEEAQSVLRILAERN--RPHGQMLGEEAQEALQDLENTCPLPATSSFSFASLLNYRNI 304
+++ L+ +A N R G L E A E T S+ R++
Sbjct: 279 GRLDLTLRALQRVARINGKREEGAKLSMEVLRASLQKELTMGKGQASAMELLRCPTLRHL 338
Query: 305 WKNLLILGF-TNFIAHAIRHCYQPVGGGGSPSDFYLCSLLASGTAALACVFLGVTVDRFG 363
+ L +L F T+F + + Q G YL ++ A + + ++ G
Sbjct: 339 FLCLSMLWFATSFAYYGLVMDLQGFG-----VSIYLIQVIFGAVDLPAKLVGFLVINSLG 393
Query: 364 RRGILLLSMTLTGIASLVLLGLWDYLNEAAITTFSVLGLFSSQAAAILSTLLAAEVIPTT 423
RR + ++ L GI ++L G+ T+ +VLG A+ L E+ PT
Sbjct: 394 RRPAQMAALLLAGIC-ILLNGVIPQDQSIVRTSLAVLGKGCLAASFNCIFLYTGELYPTM 452
Query: 424 VRGRGLGLIMALGALGGLSGP----AQRLHMGHGAFLQHVVLAACALLCILSIMLLPETK 479
+R G+G+ + +G + P L+ F+ V A + + + LLPET
Sbjct: 453 IRQTGMGMGSTMARVGSIVSPLVSMTAELYPSMPLFIYGAVPVAASAVTV----LLPETL 508
Query: 480 RKLLPEVLRDGE 491
+ LP+ ++D E
Sbjct: 509 GQPLPDTVQDLE 520
>gi|42542386 solute carrier family 22 (organic anion/cation
transporter), member 9 [Homo sapiens]
Length = 553
Score = 120 bits (300), Expect = 4e-27
Identities = 138/532 (25%), Positives = 224/532 (42%), Gaps = 75/532 (14%)
Query: 6 IFTLAPPLHC---HYGAFPPNASGWEQPPNASGVSVA-SAALAASAASRVATSTDPS--- 58
IF +A LH ++ AF P W + VS + AL+ A R++ D +
Sbjct: 26 IFAVATYLHFMLENFTAFIPGHRCWVHILDNDTVSDNDTGALSQDALLRISIPLDSNMRP 85
Query: 59 --CSGFAPP-----------------DFNHCLKDWDYNGLPVLTTNAIGQWDLVCDLGWQ 99
C F P D C+ W Y+ + +T + +WDLVCD
Sbjct: 86 EKCRRFVHPQWQLLHLNGTFPNTSDADMEPCVDGWVYDRISFSST-IVTEWDLVCDSQSL 144
Query: 100 VILEQILFILGFASGYLFLGYPADRFGRRGIV---LLTLGLVGPCGVGGAAAGSSTGVMA 156
+ + +F+ G G + G+ +DRFGRR ++ L + +VG C A A + +
Sbjct: 145 TSVAKFVFMAGMMVGGILGGHLSDRFGRRFVLRWCYLQVAIVGTCA---ALAPTFLIYCS 201
Query: 157 LRFLLGFLLAGVDLGVYLMRLELCDPTQRLRVALAGELVGV---GGHFLFL-GLALVSKD 212
LRFL G + ++ E T R + G +G+ G F+ L GLA +D
Sbjct: 202 LRFLSGIAAMSLITNTIMLIAEWA--THRFQAM--GITLGMCPSGIAFMTLAGLAFAIRD 257
Query: 213 WRFLQRMITAPC-ILFLFYGWPGLFLESARWLIVKRQIEEAQSVLRILAERNRPHG---- 267
W LQ +++ P ++FL W LESARWLI+ + EE LR A R+
Sbjct: 258 WHILQLVVSVPYFVIFLTSSW---LLESARWLIINNKPEEGLKELRKAAHRSGMKNARDT 314
Query: 268 ---QMLGEEAQEALQDLENTCPLPATSSFSFASLLNYRNIWKNLLILGFT---NFIAH-A 320
++L ++ L+ + P S +L+ NI K + +L FT NF+A+
Sbjct: 315 LTLEILKSTMKKELEAAQKKKP-------SLCEMLHMPNICKRISLLSFTRFANFMAYFG 367
Query: 321 IRHCYQPVGGGGSPSDFYLCSLLASGTAALACVFLGVTVDRFGRRGILLLSMTLTGIASL 380
+ Q +G ++ +L L LA + RR +L M L I L
Sbjct: 368 LNLHVQHLG-----NNVFLLQTLFGAVILLANCVAPWALKYMNRRASQMLLMFLLAICLL 422
Query: 381 VLLGLWDYLNEAAITTFSVLGLFSSQAAAILSTLLAA---EVIPTTVRGRGLGLIMALGA 437
++ ++ + T VL A+A+ +TL A EVIPT +R R +G+
Sbjct: 423 AII----FVPQEMQTLREVLATLGLGASALANTLAFAHGNEVIPTIIRARAMGINATFAN 478
Query: 438 LGGLSGPAQRLHMGHGAFLQHVVLAACALLCILSIMLLPETKRKLLPEVLRD 489
+ G P + + L ++ + + +LLPET+ K L + ++D
Sbjct: 479 IAGALAPLMMILSVYSPPLPWIIYGVFPFISGFAFLLLPETRNKPLFDTIQD 530
>gi|24497485 urate anion exchanger 1 isoform a [Homo sapiens]
Length = 553
Score = 119 bits (298), Expect = 7e-27
Identities = 113/438 (25%), Positives = 185/438 (42%), Gaps = 18/438 (4%)
Query: 58 SCSGFAPPDFNHCLKDWDYNGLPVLTTNAIGQWDLVCDLGWQVILEQILFILGFASGYLF 117
+ + ++ D C+ W Y+ + T+ + +W+LVCD + Q +++ G G
Sbjct: 104 TATSWSEADTEPCVDGWVYDR-SIFTSTIVAKWNLVCDSHALKPMAQSIYLAGILVGAAA 162
Query: 118 LGYPADRFGRRGIVLLTLGLVGPCGVGGAAAGSSTGVMALRFLLGFLLAGVDLGVYLMRL 177
G +DRFGRR ++ + + G A A + RFLL F +AGV + + +
Sbjct: 163 CGPASDRFGRRLVLTWSYLQMAVMGTAAAFAPAFPVYCLFRFLLAFAVAGVMMNTGTLLM 222
Query: 178 ELCDPTQRLRVALAGELVGVGGHFLFLGLALVSKDWRFLQRMITAPCILFLFYGWPGLFL 237
E R V L GH L +A +DW LQ +++ P L Y W
Sbjct: 223 EWTAARARPLVMTLNSLGFSFGHGLTAAVAYGVRDWTLLQLVVSVPFFLCFLYSW--WLA 280
Query: 238 ESARWLIVKRQIE-EAQSVLRILAERNRPHGQMLGEEAQEAL-----QDLENTCPLPATS 291
ESARWL+ +++ Q + R+ A + G + E L ++L P +
Sbjct: 281 ESARWLLTTGRLDWGLQELWRVAAINGK--GAVQDTLTPEVLLSAMREELSMGQPPASLG 338
Query: 292 SFSFASLLNYRNIWKNLLILGFTNFIAHAIRHCYQPVGGGGSPSDFYLCSLLASGTAALA 351
+ L +R L F F + Q +G S+ +L + A
Sbjct: 339 TLLRMPGLRFRTCISTLCWFAF-GFTFFGLALDLQALG-----SNIFLLQMFIGVVDIPA 392
Query: 352 CVFLGVTVDRFGRRGILLLSMTLTGIASLVLLGLWDYLNEAAITTFSVLGLFSSQAAAIL 411
+ + + GRR L S+ L G+ L L + A + +VLGL AA
Sbjct: 393 KMGALLLLSHLGRRPTLAASLLLAGLCILANT-LVPHEMGALRSALAVLGLGGVGAAFTC 451
Query: 412 STLLAAEVIPTTVRGRGLGLIMALGALGGLSGPAQRLHMGHGAFLQHVVLAACALLCILS 471
T+ ++E+ PT +R +GL G + GP RL HG +L +V +L L+
Sbjct: 452 ITIYSSELFPTVLRMTAVGLGQMAARGGAILGPLVRLLGVHGPWLPLLVYGTVPVLSGLA 511
Query: 472 IMLLPETKRKLLPEVLRD 489
+LLPET+ LP+ ++D
Sbjct: 512 ALLLPETQSLPLPDTIQD 529
>gi|153791484 putative UST1-like organic anion transporter [Homo
sapiens]
Length = 547
Score = 118 bits (296), Expect = 1e-26
Identities = 119/434 (27%), Positives = 184/434 (42%), Gaps = 20/434 (4%)
Query: 65 PDFNHCLKDWDYNGLPVLTTNAIGQWDLVCDLGWQVILEQILFILGFASGYLFLGYPADR 124
PD C+ W Y+ +T + +WDLVC+ + + LF+ G G G+ +DR
Sbjct: 111 PDTEPCVDGWVYDQSSFPST-IVTKWDLVCESQPLNSVAKFLFMAGMMVGGNLYGHLSDR 169
Query: 125 FGRRGIV---LLTLGLVGPCGVGGAAAGSSTGVMALRFLLGFLLAGVDLGVYLMRLELCD 181
FGR+ ++ L L +VG C A A + +LRFL G + + L+ +E
Sbjct: 170 FGRKFVLRWSYLQLAIVGTCA---AFAPTILVYCSLRFLAGAATFSIIVNTVLLIVEWIT 226
Query: 182 PTQRLRVALAGELVGVG-GHFLFLGLALVSKDWRFLQRMITAPC-ILFLFYGWPGLFLES 239
Q +AL L GH LA V +D LQ +++APC + FLF W ES
Sbjct: 227 H-QFCAMALTLTLCAASIGHITLGSLAFVIRDQCILQLVMSAPCFVFFLFSRW---LAES 282
Query: 240 ARWLIVKRQIEEAQSVLRILAERNRPHGQMLGEE--AQEALQDLENTCPLPATSSFSFAS 297
ARWLI+ + EE LR A RN G E+ E L+ A S
Sbjct: 283 ARWLIINNKPEEGLKELRKAAHRN---GMKNAEDILTMEVLKSTMKQELEAAQKKHSLCE 339
Query: 298 LLNYRNIWKNLLILGFTNFIAHAIRHCYQPVGGGGSPSDFYLCSLLASGTAALACVFLGV 357
LL NI K + L F F A I + ++ +L L LA
Sbjct: 340 LLRIPNICKRICFLSFVRF-ASTIPFWGLTLHLQHLGNNVFLLQTLFGAVTLLANCVAPW 398
Query: 358 TVDRFGRRGILLLSMTLTGIASLVLLGLWDYLNEAAITTFSVLGLFSSQAAAILSTLLAA 417
++ RR +L M L L ++ + + + + LG+ ++ ST
Sbjct: 399 ALNHMSRRLSQMLLMFLLATCLLAIIFVPQEMQTLRV-VLATLGVGAASLGITCSTAQEN 457
Query: 418 EVIPTTVRGRGLGLIMALGALGGLSGPAQRLHMGHGAFLQHVVLAACALLCILSIMLLPE 477
E+IP+ +RGR G+ +GG + + L ++ A+L L ++LLPE
Sbjct: 458 ELIPSIIRGRATGITGNFANIGGALASLMMILSIYSRPLPWIIYGVFAILSGLVVLLLPE 517
Query: 478 TKRKLLPEVLRDGE 491
T+ + L + ++D E
Sbjct: 518 TRNQPLLDSIQDVE 531
>gi|211059435 solute carrier family 22, member 24 [Homo sapiens]
Length = 551
Score = 113 bits (283), Expect = 4e-25
Identities = 119/437 (27%), Positives = 181/437 (41%), Gaps = 26/437 (5%)
Query: 65 PDFNHCLKDWDYNGLPVLTTNAIGQWDLVCDLGWQVILEQILFILGFASGYLFLGYPADR 124
PD C+ W Y+ L+T + +WDLVC+ + Q LF+ G G L G+ +DR
Sbjct: 111 PDTEPCVDGWVYDRSSFLST-IVTEWDLVCESQSLKSMVQSLFMAGSLLGGLIYGHLSDR 169
Query: 125 FGRRGIVLLTLGLVGPCGVGGAAAGSSTGVMALRFLLGFLLAGVDLGVYLMRLELCDPTQ 184
GR+ I L + A A + LRFL GF + +++ LE P
Sbjct: 170 VGRKIICKLCFLQLAISNTCAAFAPTFLVYCILRFLAGFSTMTILGNTFILSLEWTLPRS 229
Query: 185 RLRVALAGELVGVGGHFLFLGLALVSKDWRFLQRMITAPCILFLFYGWPGLFLESARWLI 244
R + G L GLA +DW LQ ++ P I+ W +ESARWLI
Sbjct: 230 RSMTIMVLLCSYSVGQMLLGGLAFAIQDWHILQLTVSTPIIVLFLSSWK--MVESARWLI 287
Query: 245 VKRQIEEAQSVLRILAERN--RPHGQMLGEEAQEALQDLENTCPLPATSSFSFASLLNYR 302
+ Q++E LR +A N + + L E + E TS FS +R
Sbjct: 288 INNQLDEGLKELRRVAHINGKKNTEETLTTELVRSTMKKELDAVRIKTSIFSL-----FR 342
Query: 303 NIWKNLLILGFTNFIAHAIRHCYQPVGG--------GGSPSDFYLCSLLASGTAALACVF 354
+ + G F+ AI P G G + S F + L + T CV
Sbjct: 343 APKLRMRVFGLC-FVRFAIT---VPFYGLILNLQHLGSNVSLFQI--LCGAVTFTARCVS 396
Query: 355 LGVTVDRFGRRGILLLSMTLTGIASLVLLGLWDYLNEAAITTFSVLGLFSSQAAAILSTL 414
L +T++ GRR +L G+ LV L + + + LG+ S AA+ +++
Sbjct: 397 L-LTLNHMGRRISQILFTFPVGLFILVNTFLPQEMQILRV-VLATLGIGSVSAASNSASV 454
Query: 415 LAAEVIPTTVRGRGLGLIMALGALGGLSGPAQRLHMGHGAFLQHVVLAACALLCILSIML 474
E++PT +R G+ G G P M + L + +L + I+L
Sbjct: 455 HHNELVPTILRSTVAGINAVSGRTGAALAPLLMTLMAYSPHLPWISYGVFPILAVPVILL 514
Query: 475 LPETKRKLLPEVLRDGE 491
LPET+ LP ++D E
Sbjct: 515 LPETRDLPLPNTIQDVE 531
>gi|238814326 solute carrier family 22, member 20 [Homo sapiens]
Length = 555
Score = 112 bits (280), Expect = 8e-25
Identities = 106/424 (25%), Positives = 177/424 (41%), Gaps = 18/424 (4%)
Query: 70 CLKDWDYNGLPVLTTNAIGQWDLVCDLGWQVILEQILFILGFASGYLFLGYPADRFGRRG 129
C W YN V + + +WDLVC+ L Q +++ G G G ADR G +G
Sbjct: 107 CKDGWVYNR-SVFPSTIVMEWDLVCEARTLRDLAQSVYMAGVLVGAAVFGSLADRLGCKG 165
Query: 130 IVLLTLGLVGPCGVGGAAAGSSTGVMALRFLLGFLLAGVDLGVYLMRLELCDPTQRLRVA 189
++ + + G A S + RFL+G +G+ L + +E R
Sbjct: 166 PLVWSYLQLAASGAATAYFSSFSAYCVFRFLMGMTFSGIILNSVSLVVEWMPTRGR---T 222
Query: 190 LAGELVGVG---GHFLFLGLALVSKDWRFLQRMITAPCILFLFYGWPGLFLESARWLIVK 246
+AG L+G G + G+A + + WR LQ I+AP ++F Y W ES+RWL++
Sbjct: 223 VAGILLGYSFTLGQLILAGVAYLIRPWRCLQFAISAPFLIFFLYSW--WLPESSRWLLLH 280
Query: 247 RQIEEAQSVLRILAERN--RPHGQMLGEEAQEALQDLENTCPLPATSSFSFASLLNYRNI 304
+ + A L+ +A N + G+ L +E + E + S R +
Sbjct: 281 GKSQLAVQNLQKVAAMNGRKEEGERLTKEVMSSYIQSEFASVCTSNSILDLFRTPAIRKV 340
Query: 305 WKNLLILGFTNFIA-HAIRHCYQPVGGGGSPSDFYLCSLLASGTAALACVFLGVTVDRFG 363
L+++ F+N +A + + Q G YL L A + T+ G
Sbjct: 341 TCCLMVIWFSNSVAYYGLAMDLQKFG-----LSLYLVQALFGIINTPAMLVATATMIYVG 395
Query: 364 RRGILLLSMTLTGIASLVLLGLWDYLNEAAITTFSVLGLFSSQAAAILSTLLAAEVIPTT 423
RR + + L G+ + + + + + T + LG ++ I L E+ PT
Sbjct: 396 RRATVASFLILAGLMVIANMFVPEG-TQILCTAQAALGKGCLASSFICVYLFTGELYPTE 454
Query: 424 VRGRGLGLIMALGALGGLSGPAQRLHMGHGAFLQHVVLAACALLCILSIMLLPETKRKLL 483
+R G+G LGGL+ P + L V A A+L L++ +L ET+ L
Sbjct: 455 IRQMGMGFASVHARLGGLTAPLVTTLGEYSTILPPVSFGATAILAGLAVCVLTETRNMPL 514
Query: 484 PEVL 487
E +
Sbjct: 515 VETI 518
>gi|148664184 solute carrier family 22, member 10 [Homo sapiens]
Length = 541
Score = 111 bits (278), Expect = 1e-24
Identities = 112/431 (25%), Positives = 179/431 (41%), Gaps = 16/431 (3%)
Query: 66 DFNHCLKDWDYNGLPVLTTNAIGQWDLVCDLGWQVILEQILFILGFASGYLFLGYPADRF 125
D C+ W Y+ + + +WDLVCD + Q L + G G + G+ +DRF
Sbjct: 112 DTEPCVDGWVYDQ-SYFPSTIVTKWDLVCDYQSLKSVVQFLLLTGMLVGGIIGGHVSDRF 170
Query: 126 GRRGIV---LLTLGLVGPCGVGGAAAGSSTGVMALRFLLGFLLAGVDLGVYLMRLELCDP 182
GRR I+ LL L + C A A + LRFL GF + L E P
Sbjct: 171 GRRFILRWCLLQLAITDTC---AAFAPTFPVYCVLRFLAGFSSMIIISNNSLPITEWIRP 227
Query: 183 TQRLRVALAGELVGVGGHFLFLGLALVSKDWRFLQRMITAPCILFLFYGWPGLFLESARW 242
+ V + G + GLA V +DW+ L + + P F+F+ +ESARW
Sbjct: 228 NSKALVVILSSGALSIGQIILGGLAYVFRDWQTLHVVASVP--FFVFFLLSRWLVESARW 285
Query: 243 LIVKRQIEEAQSVLRILAERN--RPHGQMLGEEAQEALQDLENTCPLPATSSFSFASLLN 300
LI+ +++E LR +A N + + L E + E A + + L
Sbjct: 286 LIITNKLDEGLKALRKVARTNGIKNAEETLNIEVVRSTMQEELDA---AQTKTTVCDLFR 342
Query: 301 YRNIWKNLLILGFTNFIAHAIRHCYQPVGGGGSPSDFYLCSLLASGTAALACVFLGVTVD 360
++ K + IL F F A+ I V S+ +L +L A + +T++
Sbjct: 343 NPSMRKRICILVFLRF-ANTIPFYGTMVNLQHVGSNIFLLQVLYGAVALIVRCLALLTLN 401
Query: 361 RFGRRGILLLSMTLTGIASLVLLGLWDYLNEAAITTFSVLGLFSSQAAAILSTLLAAEVI 420
GRR +L M L G++ L + + + + LG+ S A + E+I
Sbjct: 402 HMGRRISQILFMFLVGLSILANTFVPKEMQTLRV-ALACLGIGCSAATFSSVAVHFIELI 460
Query: 421 PTTVRGRGLGLIMALGALGGLSGPAQRLHMGHGAFLQHVVLAACALLCILSIMLLPETKR 480
PT +R R G+ + +G P L ++ ++ L + LLPETK
Sbjct: 461 PTVLRARASGIDLTASRIGAALAPLLMTLTVFFTTLPWIIYGIFPIIGGLIVFLLPETKN 520
Query: 481 KLLPEVLRDGE 491
LP+ ++D E
Sbjct: 521 LPLPDTIKDVE 531
>gi|24497480 solute carrier family 22 member 6 isoform d [Homo
sapiens]
Length = 519
Score = 106 bits (264), Expect = 6e-23
Identities = 103/373 (27%), Positives = 155/373 (41%), Gaps = 18/373 (4%)
Query: 70 CLKDWDYNGLPVLTTNAIGQWDLVCDLGWQVILEQILFILGFASGYLFLGYPADRFGRRG 129
C W Y+ +T + +WDLVC L Q L+++G G + GY ADR GRR
Sbjct: 105 CTDGWIYDNSTFPST-IVTEWDLVCSHRALRQLAQSLYMVGVLLGAMVFGYLADRLGRRK 163
Query: 130 IVLLTLGLVGPCGVGGAAAGSSTGVMALRFLLGFLLAGVDLGVYLMRLELCDPTQRLRVA 189
+++L G A A + A R L G LAG+ L + +E R A
Sbjct: 164 VLILNYLQTAVSGTCAAFAPNFPIYCAFRLLSGMALAGISLNCMTLNVEWMPIHTR---A 220
Query: 190 LAGELVGVG---GHFLFLGLALVSKDWRFLQRMITAPCILFLFYGWPGLFLESARWLIVK 246
G L+G G FL G+A WR LQ +++AP F Y W F+ESARW
Sbjct: 221 CVGTLIGYVYSLGQFLLAGVAYAVPHWRHLQLLVSAPFFAFFIYSW--FFIESARWHSSS 278
Query: 247 RQIEEAQSVLRILAERN--RPHGQMLGEEAQEALQDLENTCPLPATSSFSFASLLNYRNI 304
+++ L+ +A N R G L E A E T S+ R++
Sbjct: 279 GRLDLTLRALQRVARINGKREEGAKLSMEVLRASLQKELTMGKGQASAMELLRCPTLRHL 338
Query: 305 WKNLLILGF-TNFIAHAIRHCYQPVGGGGSPSDFYLCSLLASGTAALACVFLGVTVDRFG 363
+ L +L F T+F + + Q G YL ++ A + + ++ G
Sbjct: 339 FLCLSMLWFATSFAYYGLVMDLQGFG-----VSIYLIQVIFGAVDLPAKLVGFLVINSLG 393
Query: 364 RRGILLLSMTLTGIASLVLLGLWDYLNEAAITTFSVLGLFSSQAAAILSTLLAAEVIPTT 423
RR + ++ L GI ++L G+ T+ +VLG A+ L E+ PT
Sbjct: 394 RRPAQMAALLLAGIC-ILLNGVIPQDQSIVRTSLAVLGKGCLAASFNCIFLYTGELYPTM 452
Query: 424 VRGRGLGLIMALG 436
+R + L LG
Sbjct: 453 IRAVTVLLPETLG 465
>gi|24497478 solute carrier family 22 member 6 isoform c [Homo
sapiens]
Length = 506
Score = 106 bits (264), Expect = 6e-23
Identities = 103/373 (27%), Positives = 155/373 (41%), Gaps = 18/373 (4%)
Query: 70 CLKDWDYNGLPVLTTNAIGQWDLVCDLGWQVILEQILFILGFASGYLFLGYPADRFGRRG 129
C W Y+ +T + +WDLVC L Q L+++G G + GY ADR GRR
Sbjct: 105 CTDGWIYDNSTFPST-IVTEWDLVCSHRALRQLAQSLYMVGVLLGAMVFGYLADRLGRRK 163
Query: 130 IVLLTLGLVGPCGVGGAAAGSSTGVMALRFLLGFLLAGVDLGVYLMRLELCDPTQRLRVA 189
+++L G A A + A R L G LAG+ L + +E R A
Sbjct: 164 VLILNYLQTAVSGTCAAFAPNFPIYCAFRLLSGMALAGISLNCMTLNVEWMPIHTR---A 220
Query: 190 LAGELVGVG---GHFLFLGLALVSKDWRFLQRMITAPCILFLFYGWPGLFLESARWLIVK 246
G L+G G FL G+A WR LQ +++AP F Y W F+ESARW
Sbjct: 221 CVGTLIGYVYSLGQFLLAGVAYAVPHWRHLQLLVSAPFFAFFIYSW--FFIESARWHSSS 278
Query: 247 RQIEEAQSVLRILAERN--RPHGQMLGEEAQEALQDLENTCPLPATSSFSFASLLNYRNI 304
+++ L+ +A N R G L E A E T S+ R++
Sbjct: 279 GRLDLTLRALQRVARINGKREEGAKLSMEVLRASLQKELTMGKGQASAMELLRCPTLRHL 338
Query: 305 WKNLLILGF-TNFIAHAIRHCYQPVGGGGSPSDFYLCSLLASGTAALACVFLGVTVDRFG 363
+ L +L F T+F + + Q G YL ++ A + + ++ G
Sbjct: 339 FLCLSMLWFATSFAYYGLVMDLQGFG-----VSIYLIQVIFGAVDLPAKLVGFLVINSLG 393
Query: 364 RRGILLLSMTLTGIASLVLLGLWDYLNEAAITTFSVLGLFSSQAAAILSTLLAAEVIPTT 423
RR + ++ L GI ++L G+ T+ +VLG A+ L E+ PT
Sbjct: 394 RRPAQMAALLLAGIC-ILLNGVIPQDQSIVRTSLAVLGKGCLAASFNCIFLYTGELYPTM 452
Query: 424 VRGRGLGLIMALG 436
+R + L LG
Sbjct: 453 IRAVTVLLPETLG 465
>gi|23510410 solute carrier family 22 member 1 isoform b [Homo
sapiens]
Length = 506
Score = 103 bits (257), Expect = 4e-22
Identities = 101/362 (27%), Positives = 160/362 (44%), Gaps = 20/362 (5%)
Query: 70 CLKDWDYNGLPVLTTNAIGQWDLVCDLGWQVILEQILFILGFASGYLFLGYPADRFGRRG 129
C W Y+ ++ + +++LVC W++ L Q GF G L +GY ADRFGR+
Sbjct: 121 CQDGWVYD---TPGSSIVTEFNLVCADSWKLDLFQSCLNAGFLFGSLGVGYFADRFGRKL 177
Query: 130 IVLLTLGLVGPCGVGGAAAGSSTGVMALRFLLGFLLAGVDLGVYLMRLELCDPTQRLRVA 189
+L T+ + GV A + + ++ R L G + G + Y + E R VA
Sbjct: 178 CLLGTVLVNAVSGVLMAFSPNYMSMLLFRLLQGLVSKGNWMAGYTLITEFVGSGSRRTVA 237
Query: 190 LAGELVGVGGHFLFLGLALVSKDWRFLQRMITAPCILFLFYGWPGLFLESARWLIVKRQI 249
+ ++ G GLA WR+LQ ++ P LFL Y W ES RWL+ +++
Sbjct: 238 IMYQMAFTVGLVALTGLAYALPHWRWLQLAVSLPTFLFLLYYW--CVPESPRWLLSQKRN 295
Query: 250 EEAQSVLRILAERNRPHGQMLGEEAQEALQDLENTCPLPATSSFSFASLLNYRNIWKN-- 307
EA ++ +A++N G+ L+ L + S SFA L + K
Sbjct: 296 TEAIKIMDHIAQKN-------GKLPPADLKMLSLEEDVTEKLSPSFADLFRTPRLRKRTF 348
Query: 308 -LLILGFTNFIAHAIRHCYQPVGGGGSPSDFYLCSLLASGTAALACVFLGVTVDRFGRRG 366
L+ L FT+ + + + G DF +L+ A +A +T+DR GR
Sbjct: 349 ILMYLWFTDSVLYQGLILHMGATSGNLYLDFLYSALVEIPGAFIAL----ITIDRVGRIY 404
Query: 367 ILLLSMTLTGIASLVLLGLWDYLNEAAITTFSVLGLFSSQAAAILSTLLAAEVIPTTVRG 426
+ +S L G A LV++ + L+ I V G A + L+ AE+ PT V G
Sbjct: 405 PMAMSNLLAGAACLVMIFISPDLHWLNIIIMCV-GRMGITIAIQMICLVNAELYPTFVSG 463
Query: 427 RG 428
G
Sbjct: 464 VG 465
>gi|8923870 solute carrier family 22 member 11 [Homo sapiens]
Length = 550
Score = 103 bits (256), Expect = 5e-22
Identities = 107/442 (24%), Positives = 183/442 (41%), Gaps = 22/442 (4%)
Query: 58 SCSGFAPPDFNHCLKDWDYNGLPVLTTNAIGQWDLVCDLGWQVILEQILFILGFASGYLF 117
+ + ++ D C+ W Y+ V T+ + +WDLVC L Q +F+ G G
Sbjct: 101 TATSWSEADTEPCVDGWVYDR-SVFTSTIVAKWDLVCSSQGLKPLSQSIFMSGILVGSFI 159
Query: 118 LGYPADRFGRRGIVLLTLGLVGPCGVGGAAAGSSTGVMALRFLLGFLLAGVDLGVYLMRL 177
G + RFGR+ ++ + G A + LRF+ F +AG+ L + +
Sbjct: 160 WGLLSYRFGRKPMLSWCCLQLAVAGTSTIFAPTFVIYCGLRFVAAFGMAGIFLSSLTLMV 219
Query: 178 ELCDPTQRLRVALAGELVGVGGHFLFLGLALVSKDWRFLQRMITAPCILFLFYGWPGLFL 237
E ++R G GLA +DWR LQ + P W
Sbjct: 220 EWTTTSRRAVTMTVVGCAFSAGQAALGGLAFALRDWRTLQLAASVPFFAISLISW--WLP 277
Query: 238 ESARWLIVKRQIEEAQSVLRILAERNRPHGQMLGEEAQEALQDLENTCPLPATSSFSFAS 297
ESARWLI+K + ++A LR +A N E ++ L ++ S+ S
Sbjct: 278 ESARWLIIKGKPDQALQELRKVARINGHK-----EAKNLTIEVLMSSVKEEVASAKEPRS 332
Query: 298 LLNYRNI----WKN--LLILGFTNFIA-HAIRHCYQPVGGGGSPSDFYLCSLLASGTAAL 350
+L+ + W++ +L++ F+ I+ + + Q +G D +L L L
Sbjct: 333 VLDLFCVPVLRWRSCAMLVVNFSLLISYYGLVFDLQSLG-----RDIFLLQALFGAVDFL 387
Query: 351 ACVFLGVTVDRFGRRGILLLSMTLTGIASLVLLGLWDYLNEAAITTFSVLGLFSSQAAAI 410
+ + GRR I S + G+A L + + L + F+VLG +
Sbjct: 388 GRATTALLLSFLGRRTIQAGSQAMAGLAILANMLVPQDLQTLRV-VFAVLGKGCFGISLT 446
Query: 411 LSTLLAAEVIPTTVRGRGLGLIMALGALGGLSGPAQRLHMGHGAFLQHVVLAACALLCIL 470
T+ AE+ PT VR G++ +G LG + GP + L ++ ++ L
Sbjct: 447 CLTIYKAELFPTPVRMTADGILHTVGRLGAMMGPLILMSRQALPLLPPLLYGVISIASSL 506
Query: 471 SIM-LLPETKRKLLPEVLRDGE 491
++ LPET+ LP+ ++D E
Sbjct: 507 VVLFFLPETQGLPLPDTIQDLE 528
>gi|31542327 solute carrier family 22, member 16 [Homo sapiens]
Length = 577
Score = 103 bits (256), Expect = 5e-22
Identities = 102/408 (25%), Positives = 172/408 (42%), Gaps = 21/408 (5%)
Query: 84 TNAIGQWDLVCDLGWQVILEQILFILGFASGYLFLGYPADRFGRRGIVLLTLGLVGPCGV 143
+ A+ QW+LVCD W +L Q LF+ G G + GY +DR GRR ++ T + G+
Sbjct: 138 STAVTQWNLVCDRKWLAMLIQPLFMFGVLLGSVTFGYFSDRLGRRVVLWATSSSMFLFGI 197
Query: 144 GGAAAGSSTGVMALRFLLGFLLAGVDLGVYLMRLELCDPTQRLRVALAGELVGVGGHFLF 203
A A MA RF L + +G + ++ +E R ++ G L
Sbjct: 198 AAAFAVDYYTFMAARFFLAMVASGYLVVGFVYVMEFIGMKSRTWASVHLHSFFAVGTLLV 257
Query: 204 LGLALVSKDWRFLQRMITAPCILFLFYGWPGLFLESARWLIVKRQIEEAQSVLRILAERN 263
+ + W Q +++ + F+ W + E+ WL+ + + EEAQ ++ I+A+ N
Sbjct: 258 ALTGYLVRTWWLYQMILSTVTVPFILCCW--VLPETPFWLLSEGRYEEAQKIVDIMAKWN 315
Query: 264 RPHGQMLGEEAQEALQDLENTCPLPATSSFSFASLLNYRNIWKNLLI--------LGFTN 315
R L E LQ + P N+ + L + LGF +
Sbjct: 316 RASSCKLSELLSLDLQGPVSNSPTEVQKHNLSYLFYNWSITKRTLTVWLIWFTGSLGFYS 375
Query: 316 FIAHAIRHCYQPVGGGGSPSDFYLCSLLASGTAALACVFLGVTVDRFGRRGILLLSMTLT 375
F +++ +GG + YL L A F+ + +D+ GRR +L S+ +
Sbjct: 376 FSLNSVN-----LGG-----NEYLNLFLLGVVEIPAYTFVCIAMDKVGRRTVLAYSLFCS 425
Query: 376 GIASLVLLGLWDYLNEAAITTFSVLGLFSSQAAAILSTLLAAEVIPTTVRGRGLGLIMAL 435
+A V++ + + T +++G F+ AA L L AE+ PT VR +G +
Sbjct: 426 ALACGVVMVIPQKHYILGVVT-AMVGKFAIGAAFGLIYLYTAELYPTIVRSLAVGSGSMV 484
Query: 436 GALGGLSGPAQRLHMGHGAFLQHVVLAACALLCILSIMLLPETKRKLL 483
L + P F+ + + ALL + + LPET K L
Sbjct: 485 CRLASILAPFSVDLSSIWIFIPQLFVGTMALLSGVLTLKLPETLGKRL 532
>gi|4507005 solute carrier family 22 member 5 [Homo sapiens]
Length = 557
Score = 102 bits (254), Expect = 8e-22
Identities = 108/452 (23%), Positives = 196/452 (43%), Gaps = 29/452 (6%)
Query: 50 RVATSTDPSCSGFAPP--------DFNHCLKDWDYNGLPVLTTNAIGQWDLVCDLGWQVI 101
R+AT + S G P + CL W+++ L+T + +W+LVC+ W+
Sbjct: 85 RLATIANFSALGLEPGRDVDLGQLEQESCLDGWEFSQDVYLST-IVTEWNLVCEDDWKAP 143
Query: 102 LEQILFILGFASGYLFLGYPADRFGRRGIVLLTLGLVGPCGVGGAAAGSSTGVMALRFLL 161
L LF +G G G +DRFGR+ ++ +T+G+ G S M F++
Sbjct: 144 LTISLFFVGVLLGSFISGQLSDRFGRKNVLFVTMGM--QTGFSFLQIFSKNFEM---FVV 198
Query: 162 GFLLAGVD-----LGVYLMRLELCDPTQRLRVALAGELVGVGGHFLFLGL-ALVSKDWRF 215
F+L G+ + +++ E+ + R+ + G + ++ L L A +DWR
Sbjct: 199 LFVLVGMGQISNYVAAFVLGTEILGKSVRIIFSTLGVCIFYAFGYMVLPLFAYFIRDWRM 258
Query: 216 LQRMITAPCILFLFYGWPGLFLESARWLIVKRQIEEAQSVLRILAERNRPHGQMLGEEAQ 275
L +T P +L + W ES RWLI + + EEA+ ++R A+ N +
Sbjct: 259 LLVALTMPGVLCVALWW--FIPESPRWLISQGRFEEAEVIIRKAAKANGIVVPSTIFDPS 316
Query: 276 EALQDLENTCPLPATSSFSFASLLNYRNIWKNLLILGFTNFIAHAIRHCYQPVGGGGSPS 335
E LQDL + S + LL NI + + I+ ++ ++ + +
Sbjct: 317 E-LQDLSS----KKQQSHNILDLLRTWNI-RMVTIMSIMLWMTISVGYFGLSLDTPNLHG 370
Query: 336 DFYLCSLLASGTAALACVFLGVTVDRFGRRGILLLSMTLTGIASLVLLGLWDYLNEAAIT 395
D ++ L++ A V + + RR + ++ L G L + + L A T
Sbjct: 371 DIFVNCFLSAMVEVPAYVLAWLLLQYLPRRYSMATALFLGGSVLLFMQLVPPDLYYLA-T 429
Query: 396 TFSVLGLFSSQAAAILSTLLAAEVIPTTVRGRGLGLIMALGALGGLSGPAQRLHMGHGAF 455
++G F AA + + AE+ PT VR G+G+ LG + P + F
Sbjct: 430 VLVMVGKFGVTAAFSMVYVYTAELYPTVVRNMGVGVSSTASRLGSILSPYFVYLGAYDRF 489
Query: 456 LQHVVLAACALLCILSIMLLPETKRKLLPEVL 487
L ++++ + +L + + LPE+ LP+ +
Sbjct: 490 LPYILMGSLTILTAILTLFLPESFGTPLPDTI 521
>gi|166197673 solute carrier family 22, member 15 [Homo sapiens]
Length = 547
Score = 99.8 bits (247), Expect = 5e-21
Identities = 109/421 (25%), Positives = 176/421 (41%), Gaps = 35/421 (8%)
Query: 84 TNAIGQWDLVCDLGWQVILEQILFILGFASGYLFLGYPADRFGRRGIVLLTLGLVGPCGV 143
T+ +W L+ + ++V F G G + G +DRFGR+ + L L +
Sbjct: 95 TSIASEWFLIANRSYKVSAASSFFFSGVFVGVISFGQLSDRFGRKKVYLTGFALDILFAI 154
Query: 144 GGAAAGSSTGVMALRFLLGFLLAGVDLGVYLMRLELCDPTQRLRVALAGELVGVGGHFLF 203
+ S RFL+G + G+ L +++ L C T ALAG +GG F
Sbjct: 155 ANGFSPSYEFFAVTRFLVGMMNGGMSLVAFVL-LNECVGTAYW--ALAG---SIGGLFFA 208
Query: 204 LGLALVS------KDWRFLQRMITAP-CILFLFYGWPGLFL-ESARWLIVKRQIEEAQSV 255
+G+A + + WR L ++ ++FL LF+ ES RWL + ++ EA+
Sbjct: 209 VGIAQYALLGYFIRSWRTLAILVNLQGTVVFLL----SLFIPESPRWLYSQGRLSEAEEA 264
Query: 256 LRILAERNRPHGQMLGEEAQEALQDLENTCPLPATSSFSFASLLNYRNIWKNLLILGFTN 315
L ++A+RNR + L + + SF L YR + + LIL F
Sbjct: 265 LYLIAKRNR---------KLKCTFSLTHPANRSCRETGSFLDLFRYRVLLGHTLILMFIW 315
Query: 316 FIAHAIRHCYQPVGG--GGSPSDFYLCSLLASGTAALACVFLGVTVDRFGRRGILLLSMT 373
F+ + + G GGS S L + C++L + FGR+ L +
Sbjct: 316 FVCSLVYYGLTLSAGDLGGSIYANLALSGLIEIPSYPLCIYL-INQKWFGRKRTLSAFLC 374
Query: 374 LTGIASLVLLGLWDYLNEAAIT-----TFSVLGLFSSQAAAILSTLLAAEVIPTTVRGRG 428
L G+A L+++ L + + + S+LG + AA + + +E+ PT +R G
Sbjct: 375 LGGLACLIVMFLPEKKDTGVFAVVNSHSLSLLGKLTISAAFNIVYIYTSELYPTVIRNVG 434
Query: 429 LGLIMALGALGGLSGPAQRLHMGHGAFLQHVVLAACALLCILSIMLLPETKRKLLPEVLR 488
LG +GG+ P L +V A L L +LLPET L E
Sbjct: 435 LGTCSMFSRVGGIIAPFIPSLKYVQWSLPFIVFGATGLTSGLLSLLLPETLNSPLLETFS 494
Query: 489 D 489
D
Sbjct: 495 D 495
>gi|24497490 solute carrier family 22 member 4 [Homo sapiens]
Length = 551
Score = 91.3 bits (225), Expect = 2e-18
Identities = 102/452 (22%), Positives = 188/452 (41%), Gaps = 31/452 (6%)
Query: 50 RVATSTDPSCSGFAPP--------DFNHCLKDWDYNGLPVLTTNAIGQWDLVCDLGWQVI 101
R+AT + S G P + CL W+++ L+T + +W+LVC+ W+V
Sbjct: 85 RLATIANFSALGLEPGRDVDLGQLEQESCLDGWEFSQDVYLST-VVTEWNLVCEDNWKVP 143
Query: 102 LEQILFILGFASGYLFLGYPADRFGRRGIVLLTLGLVGPCGVGGAAAGSSTGVMALRFLL 161
L LF +G G G +DRFGR+ ++ T+ + G S + M F +
Sbjct: 144 LTTSLFFVGVLLGSFVSGQLSDRFGRKNVLFATMAV--QTGFSFLQIFSISWEM---FTV 198
Query: 162 GFLLAGVD-----LGVYLMRLELCDPTQRLRVALAGELVGVGGHFLFLGL-ALVSKDWRF 215
F++ G+ + +++ E+ + R+ + G ++ L L A +DWR
Sbjct: 199 LFVIVGMGQISNYVVAFILGTEILGKSVRIIFSTLGVCTFFAVGYMLLPLFAYFIRDWRM 258
Query: 216 LQRMITAPCILFLFYGWPGLFLESARWLIVKRQIEEAQSVLRILAERNRPHGQMLGEEAQ 275
L +T P +L + W ES RWLI +R+ EA+ +++ A+ N + ++
Sbjct: 259 LLLALTVPGVLCVPLWW--FIPESPRWLISQRRFREAEDIIQKAAKMNNIAVPAVIFDSV 316
Query: 276 EALQDLENTCPLPATSSFSFASLLNYRNIWKNLLILGFTNFIAHAIRHCYQPVGGGGSPS 335
E L PL +F L RNI + I+ ++ ++ + +
Sbjct: 317 EELN------PLKQQKAF-ILDLFRTRNI-AIMTIMSLLLWMLTSVGYFALSLDAPNLHG 368
Query: 336 DFYLCSLLASGTAALACVFLGVTVDRFGRRGILLLSMTLTGIASLVLLGLWDYLNEAAIT 395
D YL L++ A + + + RR ++ ++ G L+ + L
Sbjct: 369 DAYLNCFLSALIEIPAYITAWLLLRTLPRR-YIIAAVLFWGGGVLLFIQLVPVDYYFLSI 427
Query: 396 TFSVLGLFSSQAAAILSTLLAAEVIPTTVRGRGLGLIMALGALGGLSGPAQRLHMGHGAF 455
+LG F +A + + AE+ PT VR +G+ +G + P +
Sbjct: 428 GLVMLGKFGITSAFSMLYVFTAELYPTLVRNMAVGVTSTASRVGSIIAPYFVYLGAYNRM 487
Query: 456 LQHVVLAACALLCILSIMLLPETKRKLLPEVL 487
L ++V+ + +L + + PE+ LPE L
Sbjct: 488 LPYIVMGSLTVLIGILTLFFPESLGMTLPETL 519
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.326 0.142 0.447
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 20,831,464
Number of Sequences: 37866
Number of extensions: 935958
Number of successful extensions: 3890
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 41
Number of HSP's successfully gapped in prelim test: 25
Number of HSP's that attempted gapping in prelim test: 3697
Number of HSP's gapped (non-prelim): 102
length of query: 520
length of database: 18,247,518
effective HSP length: 107
effective length of query: 413
effective length of database: 14,195,856
effective search space: 5862888528
effective search space used: 5862888528
T: 11
A: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.6 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.