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Search of human proteins with 63252902
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|63252902 tropomyosin 1 alpha chain isoform 2 [Homo sapiens]
(284 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|63252902 tropomyosin 1 alpha chain isoform 2 [Homo sapiens] 530 e-151
gi|63252906 tropomyosin 1 alpha chain isoform 7 [Homo sapiens] 499 e-142
gi|63252896 tropomyosin 1 alpha chain isoform 3 [Homo sapiens] 480 e-136
gi|63252900 tropomyosin 1 alpha chain isoform 4 [Homo sapiens] 450 e-127
gi|63252898 tropomyosin 1 alpha chain isoform 1 [Homo sapiens] 434 e-122
gi|223555975 tropomyosin 4 isoform 1 [Homo sapiens] 423 e-119
gi|114155140 tropomyosin 3 isoform 1 [Homo sapiens] 407 e-114
gi|47519616 tropomyosin 2 (beta) isoform 2 [Homo sapiens] 407 e-114
gi|27597085 tropomyosin 1 alpha chain isoform 5 [Homo sapiens] 405 e-113
gi|42476296 tropomyosin 2 (beta) isoform 1 [Homo sapiens] 397 e-111
gi|114155144 tropomyosin 3 isoform 4 [Homo sapiens] 343 8e-95
gi|63252904 tropomyosin 1 alpha chain isoform 6 [Homo sapiens] 339 2e-93
gi|4507651 tropomyosin 4 isoform 2 [Homo sapiens] 338 2e-93
gi|114155148 tropomyosin 3 isoform 5 [Homo sapiens] 323 8e-89
gi|24119203 tropomyosin 3 isoform 2 [Homo sapiens] 322 2e-88
gi|114155146 tropomyosin 3 isoform 3 [Homo sapiens] 302 2e-82
gi|224922812 tropomyosin 2 (beta) isoform 3 [Homo sapiens] 280 8e-76
gi|12667788 myosin, heavy polypeptide 9, non-muscle [Homo sapiens] 91 1e-18
gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo sap... 86 5e-17
gi|239745079 PREDICTED: Putative golgin subfamily A member 6-lik... 83 3e-16
gi|13124879 smooth muscle myosin heavy chain 11 isoform SM1A [Ho... 83 3e-16
gi|92091586 smooth muscle myosin heavy chain 11 isoform SM1B [Ho... 83 3e-16
gi|92091583 smooth muscle myosin heavy chain 11 isoform SM2B [Ho... 83 3e-16
gi|13124875 smooth muscle myosin heavy chain 11 isoform SM2A [Ho... 83 3e-16
gi|239745153 PREDICTED: similar to Putative golgin subfamily A m... 82 7e-16
gi|239745127 PREDICTED: similar to Putative golgin subfamily A m... 82 7e-16
gi|46049114 M-phase phosphoprotein 1 [Homo sapiens] 81 1e-15
gi|41406064 myosin, heavy polypeptide 10, non-muscle [Homo sapiens] 80 2e-15
gi|145312241 differentially expressed in FDCP 6 homolog [Homo sa... 79 5e-15
gi|30581135 structural maintenance of chromosomes 1A [Homo sapiens] 78 8e-15
>gi|63252902 tropomyosin 1 alpha chain isoform 2 [Homo sapiens]
Length = 284
Score = 530 bits (1365), Expect = e-151
Identities = 284/284 (100%), Positives = 284/284 (100%)
Query: 1 MDAIKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEEDIAAKEKLLRVSEDERDRV 60
MDAIKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEEDIAAKEKLLRVSEDERDRV
Sbjct: 1 MDAIKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEEDIAAKEKLLRVSEDERDRV 60
Query: 61 LEELHKAEDSLLAAEEAAAKAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAA 120
LEELHKAEDSLLAAEEAAAKAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAA
Sbjct: 61 LEELHKAEDSLLAAEEAAAKAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAA 120
Query: 121 DESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAE 180
DESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAE
Sbjct: 121 DESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAE 180
Query: 181 ERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKEDRYEEEIKVLSDKLKEAETRAE 240
ERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKEDRYEEEIKVLSDKLKEAETRAE
Sbjct: 181 ERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKEDRYEEEIKVLSDKLKEAETRAE 240
Query: 241 FAERSVTKLEKSIDDLEEKVAHAKEENLSMHQMLDQTLLELNNM 284
FAERSVTKLEKSIDDLEEKVAHAKEENLSMHQMLDQTLLELNNM
Sbjct: 241 FAERSVTKLEKSIDDLEEKVAHAKEENLSMHQMLDQTLLELNNM 284
>gi|63252906 tropomyosin 1 alpha chain isoform 7 [Homo sapiens]
Length = 284
Score = 499 bits (1286), Expect = e-142
Identities = 268/284 (94%), Positives = 275/284 (96%)
Query: 1 MDAIKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEEDIAAKEKLLRVSEDERDRV 60
MDAIKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEEDIAAKEKLLRVSEDERDRV
Sbjct: 1 MDAIKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEEDIAAKEKLLRVSEDERDRV 60
Query: 61 LEELHKAEDSLLAAEEAAAKAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAA 120
LEELHKAEDSLLAAEEAAAKAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAA
Sbjct: 61 LEELHKAEDSLLAAEEAAAKAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAA 120
Query: 121 DESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAE 180
DESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAE
Sbjct: 121 DESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAE 180
Query: 181 ERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKEDRYEEEIKVLSDKLKEAETRAE 240
ERAELSEG+ +LEE+L+ + LK+L A +KYSQKEDRYEEEIKVLSDKLKEAETRAE
Sbjct: 181 ERAELSEGQVRQLEEQLRIMDQTLKALMAAEDKYSQKEDRYEEEIKVLSDKLKEAETRAE 240
Query: 241 FAERSVTKLEKSIDDLEEKVAHAKEENLSMHQMLDQTLLELNNM 284
FAERSVTKLEKSIDDLEEKVAHAKEENLSMHQMLDQTLLELNNM
Sbjct: 241 FAERSVTKLEKSIDDLEEKVAHAKEENLSMHQMLDQTLLELNNM 284
>gi|63252896 tropomyosin 1 alpha chain isoform 3 [Homo sapiens]
Length = 284
Score = 480 bits (1236), Expect = e-136
Identities = 257/284 (90%), Positives = 268/284 (94%)
Query: 1 MDAIKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEEDIAAKEKLLRVSEDERDRV 60
MDAIKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLE+++ + +K L+ +EDE D+
Sbjct: 1 MDAIKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTEDELDKY 60
Query: 61 LEELHKAEDSLLAAEEAAAKAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAA 120
E L A++ L AE+ A AEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAA
Sbjct: 61 SEALKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAA 120
Query: 121 DESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAE 180
DESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAE
Sbjct: 121 DESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAE 180
Query: 181 ERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKEDRYEEEIKVLSDKLKEAETRAE 240
ERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKEDRYEEEIKVLSDKLKEAETRAE
Sbjct: 181 ERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKEDRYEEEIKVLSDKLKEAETRAE 240
Query: 241 FAERSVTKLEKSIDDLEEKVAHAKEENLSMHQMLDQTLLELNNM 284
FAERSVTKLEKSIDDLEEKVAHAKEENLSMHQMLDQTLLELNNM
Sbjct: 241 FAERSVTKLEKSIDDLEEKVAHAKEENLSMHQMLDQTLLELNNM 284
>gi|63252900 tropomyosin 1 alpha chain isoform 4 [Homo sapiens]
Length = 284
Score = 450 bits (1157), Expect = e-127
Identities = 241/284 (84%), Positives = 259/284 (91%)
Query: 1 MDAIKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEEDIAAKEKLLRVSEDERDRV 60
MDAIKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLE+++ + +K L+ +EDE D+
Sbjct: 1 MDAIKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTEDELDKY 60
Query: 61 LEELHKAEDSLLAAEEAAAKAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAA 120
E L A++ L AE+ A AEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAA
Sbjct: 61 SEALKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAA 120
Query: 121 DESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAE 180
DESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAE
Sbjct: 121 DESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAE 180
Query: 181 ERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKEDRYEEEIKVLSDKLKEAETRAE 240
ERAELSEG+ +LEE+L+ + LK+L A +KYSQKEDRYEEEIKVLSDKLKEAETRAE
Sbjct: 181 ERAELSEGQVRQLEEQLRIMDQTLKALMAAEDKYSQKEDRYEEEIKVLSDKLKEAETRAE 240
Query: 241 FAERSVTKLEKSIDDLEEKVAHAKEENLSMHQMLDQTLLELNNM 284
FAERSVTKLEKSIDDLEEKVAHAKEENLSMHQMLDQTLLELNNM
Sbjct: 241 FAERSVTKLEKSIDDLEEKVAHAKEENLSMHQMLDQTLLELNNM 284
>gi|63252898 tropomyosin 1 alpha chain isoform 1 [Homo sapiens]
Length = 284
Score = 434 bits (1116), Expect = e-122
Identities = 234/284 (82%), Positives = 256/284 (90%)
Query: 1 MDAIKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEEDIAAKEKLLRVSEDERDRV 60
MDAIKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLE+++ + +K L+ +EDE D+
Sbjct: 1 MDAIKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTEDELDKY 60
Query: 61 LEELHKAEDSLLAAEEAAAKAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAA 120
E L A++ L AE+ A AEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAA
Sbjct: 61 SEALKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAA 120
Query: 121 DESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAE 180
DESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAE
Sbjct: 121 DESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAE 180
Query: 181 ERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKEDRYEEEIKVLSDKLKEAETRAE 240
ERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKEDRYEEEIKVLSDKLKEAETRAE
Sbjct: 181 ERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKEDRYEEEIKVLSDKLKEAETRAE 240
Query: 241 FAERSVTKLEKSIDDLEEKVAHAKEENLSMHQMLDQTLLELNNM 284
FAERSVTKLEKSIDDLE+++ K + ++ + LD L ++ ++
Sbjct: 241 FAERSVTKLEKSIDDLEDELYAQKLKYKAISEELDHALNDMTSI 284
>gi|223555975 tropomyosin 4 isoform 1 [Homo sapiens]
Length = 284
Score = 423 bits (1088), Expect = e-119
Identities = 221/282 (78%), Positives = 253/282 (89%)
Query: 1 MDAIKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEEDIAAKEKLLRVSEDERDRV 60
M+AIKKKMQMLKLDKENA+DRAEQAEADKKAAED+ KQ+EE++ +K L+ +EDE D+
Sbjct: 1 MEAIKKKMQMLKLDKENAIDRAEQAEADKKAAEDKCKQVEEELTHLQKKLKGTEDELDKY 60
Query: 61 LEELHKAEDSLLAAEEAAAKAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAA 120
E+L A++ L E+ A+ AE DVA+LNRRIQLVEEELDRAQERLATALQKLEEAEKAA
Sbjct: 61 SEDLKDAQEKLELTEKKASDAEGDVAALNRRIQLVEEELDRAQERLATALQKLEEAEKAA 120
Query: 121 DESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAE 180
DESERGMKVIE+RA KDEEKMEIQE+QLKEAKHIAE+ADRKYEEVARKLVI+E +LERAE
Sbjct: 121 DESERGMKVIENRAMKDEEKMEIQEMQLKEAKHIAEEADRKYEEVARKLVILEGELERAE 180
Query: 181 ERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKEDRYEEEIKVLSDKLKEAETRAE 240
ERAE+SE KC +LEEELK VTNNLKSLEA +EKYS+KED+YEEEIK+LSDKLKEAETRAE
Sbjct: 181 ERAEVSELKCGDLEEELKNVTNNLKSLEAASEKYSEKEDKYEEEIKLLSDKLKEAETRAE 240
Query: 241 FAERSVTKLEKSIDDLEEKVAHAKEENLSMHQMLDQTLLELN 282
FAER+V KLEK+IDDLEEK+A AKEEN+ +HQ LDQTL ELN
Sbjct: 241 FAERTVAKLEKTIDDLEEKLAQAKEENVGLHQTLDQTLNELN 282
>gi|114155140 tropomyosin 3 isoform 1 [Homo sapiens]
Length = 285
Score = 407 bits (1047), Expect = e-114
Identities = 216/284 (76%), Positives = 251/284 (88%)
Query: 1 MDAIKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEEDIAAKEKLLRVSEDERDRV 60
M+AIKKKMQMLKLDKENALDRAEQAEA++K AE+RSKQLE+++AA +K L+ +EDE D+
Sbjct: 2 MEAIKKKMQMLKLDKENALDRAEQAEAEQKQAEERSKQLEDELAAMQKKLKGTEDELDKY 61
Query: 61 LEELHKAEDSLLAAEEAAAKAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAA 120
E L A++ L AE+ AA AEA+VASLNRRIQLVEEELDRAQERLATALQKLEEAEKAA
Sbjct: 62 SEALKDAQEKLELAEKKAADAEAEVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAA 121
Query: 121 DESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAE 180
DESERGMKVIE+RA KDEEKME+QEIQLKEAKHIAE+ADRKYEEVARKLVIIE DLER E
Sbjct: 122 DESERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKYEEVARKLVIIEGDLERTE 181
Query: 181 ERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKEDRYEEEIKVLSDKLKEAETRAE 240
ERAEL+E KC+ELEEELK VTNNLKSLEAQAEKYSQKED+YEEEIK+L+DKLKEAETRAE
Sbjct: 182 ERAELAESKCSELEEELKNVTNNLKSLEAQAEKYSQKEDKYEEEIKILTDKLKEAETRAE 241
Query: 241 FAERSVTKLEKSIDDLEEKVAHAKEENLSMHQMLDQTLLELNNM 284
FAERSV KLEK+IDDLE+++ K + ++ + LD L ++ ++
Sbjct: 242 FAERSVAKLEKTIDDLEDELYAQKLKYKAISEELDHALNDMTSI 285
>gi|47519616 tropomyosin 2 (beta) isoform 2 [Homo sapiens]
Length = 284
Score = 407 bits (1045), Expect = e-114
Identities = 214/284 (75%), Positives = 248/284 (87%)
Query: 1 MDAIKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEEDIAAKEKLLRVSEDERDRV 60
MDAIKKKMQMLKLDKENA+DRAEQAEADKK AEDR KQLEE+ A +K L+ +EDE ++
Sbjct: 1 MDAIKKKMQMLKLDKENAIDRAEQAEADKKQAEDRCKQLEEEQQALQKKLKGTEDEVEKY 60
Query: 61 LEELHKAEDSLLAAEEAAAKAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAA 120
E + +A++ L AE+ A AEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAA
Sbjct: 61 SESVKEAQEKLEQAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAA 120
Query: 121 DESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAE 180
DESERGMKVIE+RA KDEEKME+QE+QLKEAKHIAED+DRKYEEVARKLVI+E +LER+E
Sbjct: 121 DESERGMKVIENRAMKDEEKMELQEMQLKEAKHIAEDSDRKYEEVARKLVILEGELERSE 180
Query: 181 ERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKEDRYEEEIKVLSDKLKEAETRAE 240
ERAE++E + +LEEEL+T+ LKSL A E+YS KED+YEEEIK+L +KLKEAETRAE
Sbjct: 181 ERAEVAESRARQLEEELRTMDQALKSLMASEEEYSTKEDKYEEEIKLLEEKLKEAETRAE 240
Query: 241 FAERSVTKLEKSIDDLEEKVAHAKEENLSMHQMLDQTLLELNNM 284
FAERSV KLEK+IDDLEE +A AKEEN+ +HQ LDQTLLELNN+
Sbjct: 241 FAERSVAKLEKTIDDLEETLASAKEENVEIHQTLDQTLLELNNL 284
>gi|27597085 tropomyosin 1 alpha chain isoform 5 [Homo sapiens]
Length = 284
Score = 405 bits (1041), Expect = e-113
Identities = 219/284 (77%), Positives = 247/284 (86%)
Query: 1 MDAIKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEEDIAAKEKLLRVSEDERDRV 60
MDAIKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLE+++ + +K L+ +EDE D+
Sbjct: 1 MDAIKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTEDELDKY 60
Query: 61 LEELHKAEDSLLAAEEAAAKAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAA 120
E L A++ L AE+ A AEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAA
Sbjct: 61 SEALKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAA 120
Query: 121 DESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAE 180
DESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAE
Sbjct: 121 DESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAE 180
Query: 181 ERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKEDRYEEEIKVLSDKLKEAETRAE 240
ERAELSEG+ +LEE+L+ + LK+L A +KYSQKEDRYEEEIKVLSDKLKEAETRAE
Sbjct: 181 ERAELSEGQVRQLEEQLRIMDQTLKALMAAEDKYSQKEDRYEEEIKVLSDKLKEAETRAE 240
Query: 241 FAERSVTKLEKSIDDLEEKVAHAKEENLSMHQMLDQTLLELNNM 284
FAERSVTKLEKSIDDLE+++ K + ++ + LD L ++ +M
Sbjct: 241 FAERSVTKLEKSIDDLEDELYAQKLKYKAISEELDHALNDMTSM 284
>gi|42476296 tropomyosin 2 (beta) isoform 1 [Homo sapiens]
Length = 284
Score = 397 bits (1019), Expect = e-111
Identities = 209/284 (73%), Positives = 246/284 (86%)
Query: 1 MDAIKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEEDIAAKEKLLRVSEDERDRV 60
MDAIKKKMQMLKLDKENA+DRAEQAEADKK AEDR KQLEE+ A +K L+ +EDE ++
Sbjct: 1 MDAIKKKMQMLKLDKENAIDRAEQAEADKKQAEDRCKQLEEEQQALQKKLKGTEDEVEKY 60
Query: 61 LEELHKAEDSLLAAEEAAAKAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAA 120
E + +A++ L AE+ A AEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAA
Sbjct: 61 SESVKEAQEKLEQAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAA 120
Query: 121 DESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAE 180
DESERGMKVIE+RA KDEEKME+QE+QLKEAKHIAED+DRKYEEVARKLVI+E +LER+E
Sbjct: 121 DESERGMKVIENRAMKDEEKMELQEMQLKEAKHIAEDSDRKYEEVARKLVILEGELERSE 180
Query: 181 ERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKEDRYEEEIKVLSDKLKEAETRAE 240
ERAE++E KC +LEEELK VTNNLKSLEAQA+KYS KED+YEEEIK+L +KLKEAETRAE
Sbjct: 181 ERAEVAESKCGDLEEELKIVTNNLKSLEAQADKYSTKEDKYEEEIKLLEEKLKEAETRAE 240
Query: 241 FAERSVTKLEKSIDDLEEKVAHAKEENLSMHQMLDQTLLELNNM 284
FAERSV KLEK+IDDLE++V K + ++ + LD L ++ ++
Sbjct: 241 FAERSVAKLEKTIDDLEDEVYAQKMKYKAISEELDNALNDITSL 284
>gi|114155144 tropomyosin 3 isoform 4 [Homo sapiens]
Length = 248
Score = 343 bits (881), Expect = 8e-95
Identities = 182/242 (75%), Positives = 207/242 (85%)
Query: 43 IAAKEKLLRVSEDERDRVLEELHKAEDSLLAAEEAAAKAEADVASLNRRIQLVEEELDRA 102
I A ++ ++V + + D E + + + A +AEA+VASLNRRIQLVEEELDRA
Sbjct: 7 IEAVKRKIQVLQQQADDAEERAERLQREVEGERRAREQAEAEVASLNRRIQLVEEELDRA 66
Query: 103 QERLATALQKLEEAEKAADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKY 162
QERLATALQKLEEAEKAADESERGMKVIE+RA KDEEKME+QEIQLKEAKHIAE+ADRKY
Sbjct: 67 QERLATALQKLEEAEKAADESERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKY 126
Query: 163 EEVARKLVIIESDLERAEERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKEDRYE 222
EEVARKLVIIE DLER EERAEL+E KC+ELEEELK VTNNLKSLEAQAEKYSQKED+YE
Sbjct: 127 EEVARKLVIIEGDLERTEERAELAESKCSELEEELKNVTNNLKSLEAQAEKYSQKEDKYE 186
Query: 223 EEIKVLSDKLKEAETRAEFAERSVTKLEKSIDDLEEKVAHAKEENLSMHQMLDQTLLELN 282
EEIK+L+DKLKEAETRAEFAERSV KLEK+IDDLE+K+ KEE+L +MLDQTLL+LN
Sbjct: 187 EEIKILTDKLKEAETRAEFAERSVAKLEKTIDDLEDKLKCTKEEHLCTQRMLDQTLLDLN 246
Query: 283 NM 284
M
Sbjct: 247 EM 248
>gi|63252904 tropomyosin 1 alpha chain isoform 6 [Homo sapiens]
Length = 245
Score = 339 bits (869), Expect = 2e-93
Identities = 187/238 (78%), Positives = 200/238 (84%)
Query: 43 IAAKEKLLRVSEDERDRVLEELHKAEDSLLAAEEAAAKAEADVASLNRRIQLVEEELDRA 102
+ A + +R +++ D E + L + AEADVASLNRRIQLVEEELDRA
Sbjct: 7 LEAVRRKIRSLQEQADAAEERAGTLQRELDHERKLRETAEADVASLNRRIQLVEEELDRA 66
Query: 103 QERLATALQKLEEAEKAADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKY 162
QERLATALQKLEEAEKAADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKY
Sbjct: 67 QERLATALQKLEEAEKAADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKY 126
Query: 163 EEVARKLVIIESDLERAEERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKEDRYE 222
EEVARKLVIIESDLERAEERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKEDRYE
Sbjct: 127 EEVARKLVIIESDLERAEERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKEDRYE 186
Query: 223 EEIKVLSDKLKEAETRAEFAERSVTKLEKSIDDLEEKVAHAKEENLSMHQMLDQTLLE 280
EEIKVLSDKLKEAETRAEFAERSVTKLEKSIDDLE+++ E+N + L L E
Sbjct: 187 EEIKVLSDKLKEAETRAEFAERSVTKLEKSIDDLEDQLYQQLEQNRRLTNELKLALNE 244
Score = 62.8 bits (151), Expect = 3e-10
Identities = 50/237 (21%), Positives = 102/237 (43%), Gaps = 35/237 (14%)
Query: 1 MDAIKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEEDIAAKEKLLRVSEDERDRV 60
++A+++K++ L+ + A +RA + + + E D+A+ + +++ E+E DR
Sbjct: 7 LEAVRRKIRSLQEQADAAEERAGTLQRELDHERKLRETAEADVASLNRRIQLVEEELDRA 66
Query: 61 LEELHKAEDSLLAAEEAAAKAEADVASLNRRIQ--------------------------- 93
E L A L AE+AA ++E + + R Q
Sbjct: 67 QERLATALQKLEEAEKAADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKY 126
Query: 94 --------LVEEELDRAQERLATALQKLEEAEKAADESERGMKVIESRAQKDEEKMEIQE 145
++E +L+RA+ER + K E E+ +K +E++A+K +K + E
Sbjct: 127 EEVARKLVIIESDLERAEERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKEDRYE 186
Query: 146 IQLKEAKHIAEDADRKYEEVARKLVIIESDLERAEERAELSEGKCAELEEELKTVTN 202
++K ++A+ + E R + +E ++ E++ + L ELK N
Sbjct: 187 EEIKVLSDKLKEAETRAEFAERSVTKLEKSIDDLEDQLYQQLEQNRRLTNELKLALN 243
>gi|4507651 tropomyosin 4 isoform 2 [Homo sapiens]
Length = 248
Score = 338 bits (868), Expect = 2e-93
Identities = 178/240 (74%), Positives = 204/240 (85%)
Query: 43 IAAKEKLLRVSEDERDRVLEELHKAEDSLLAAEEAAAKAEADVASLNRRIQLVEEELDRA 102
+ A ++ ++ + + D + + L E KAE DVA+LNRRIQLVEEELDRA
Sbjct: 7 LEAVKRKIQALQQQADEAEDRAQGLQRELDGERERREKAEGDVAALNRRIQLVEEELDRA 66
Query: 103 QERLATALQKLEEAEKAADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKY 162
QERLATALQKLEEAEKAADESERGMKVIE+RA KDEEKMEIQE+QLKEAKHIAE+ADRKY
Sbjct: 67 QERLATALQKLEEAEKAADESERGMKVIENRAMKDEEKMEIQEMQLKEAKHIAEEADRKY 126
Query: 163 EEVARKLVIIESDLERAEERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKEDRYE 222
EEVARKLVI+E +LERAEERAE+SE KC +LEEELK VTNNLKSLEA +EKYS+KED+YE
Sbjct: 127 EEVARKLVILEGELERAEERAEVSELKCGDLEEELKNVTNNLKSLEAASEKYSEKEDKYE 186
Query: 223 EEIKVLSDKLKEAETRAEFAERSVTKLEKSIDDLEEKVAHAKEENLSMHQMLDQTLLELN 282
EEIK+LSDKLKEAETRAEFAER+V KLEK+IDDLEEK+A AKEEN+ +HQ LDQTL ELN
Sbjct: 187 EEIKLLSDKLKEAETRAEFAERTVAKLEKTIDDLEEKLAQAKEENVGLHQTLDQTLNELN 246
>gi|114155148 tropomyosin 3 isoform 5 [Homo sapiens]
Length = 247
Score = 323 bits (829), Expect = 8e-89
Identities = 174/239 (72%), Positives = 198/239 (82%)
Query: 43 IAAKEKLLRVSEDERDRVLEELHKAEDSLLAAEEAAAKAEADVASLNRRIQLVEEELDRA 102
I A ++ ++V + + D E + + + A +AEA+VASLNRRIQLVEEELDRA
Sbjct: 7 IEAVKRKIQVLQQQADDAEERAERLQREVEGERRAREQAEAEVASLNRRIQLVEEELDRA 66
Query: 103 QERLATALQKLEEAEKAADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKY 162
QERLATALQKLEEAEKAADESERGMKVIE+RA KDEEKME+QEIQLKEAKHIAE+ADRKY
Sbjct: 67 QERLATALQKLEEAEKAADESERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKY 126
Query: 163 EEVARKLVIIESDLERAEERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKEDRYE 222
EEVARKLVIIE DLER EERAEL+E KC+ELEEELK VTNNLKSLEAQAEKYSQKED+YE
Sbjct: 127 EEVARKLVIIEGDLERTEERAELAESKCSELEEELKNVTNNLKSLEAQAEKYSQKEDKYE 186
Query: 223 EEIKVLSDKLKEAETRAEFAERSVTKLEKSIDDLEEKVAHAKEENLSMHQMLDQTLLEL 281
EEIK+L+DKLKEAETRAEFAERSV KLEK+IDDLEE++ E N + L TL +L
Sbjct: 187 EEIKILTDKLKEAETRAEFAERSVAKLEKTIDDLEERLYSQLERNRLLSNELKLTLHDL 245
>gi|24119203 tropomyosin 3 isoform 2 [Homo sapiens]
Length = 248
Score = 322 bits (826), Expect = 2e-88
Identities = 169/242 (69%), Positives = 200/242 (82%)
Query: 43 IAAKEKLLRVSEDERDRVLEELHKAEDSLLAAEEAAAKAEADVASLNRRIQLVEEELDRA 102
I A ++ ++V + + D E + + + A +AEA+VASLNRRIQLVEEELDRA
Sbjct: 7 IEAVKRKIQVLQQQADDAEERAERLQREVEGERRAREQAEAEVASLNRRIQLVEEELDRA 66
Query: 103 QERLATALQKLEEAEKAADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKY 162
QERLATALQKLEEAEKAADESERGMKVIE+RA KDEEKME+QEIQLKEAKHIAE+ADRKY
Sbjct: 67 QERLATALQKLEEAEKAADESERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKY 126
Query: 163 EEVARKLVIIESDLERAEERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKEDRYE 222
EEVARKLVIIE DLER EERAEL+E +C E++E+++ + NLK L A EKYSQKED+YE
Sbjct: 127 EEVARKLVIIEGDLERTEERAELAESRCREMDEQIRLMDQNLKCLSAAEEKYSQKEDKYE 186
Query: 223 EEIKVLSDKLKEAETRAEFAERSVTKLEKSIDDLEEKVAHAKEENLSMHQMLDQTLLELN 282
EEIK+L+DKLKEAETRAEFAERSV KLEK+IDDLE+K+ KEE+L +MLDQTLL+LN
Sbjct: 187 EEIKILTDKLKEAETRAEFAERSVAKLEKTIDDLEDKLKCTKEEHLCTQRMLDQTLLDLN 246
Query: 283 NM 284
M
Sbjct: 247 EM 248
>gi|114155146 tropomyosin 3 isoform 3 [Homo sapiens]
Length = 247
Score = 302 bits (774), Expect = 2e-82
Identities = 161/239 (67%), Positives = 191/239 (79%)
Query: 43 IAAKEKLLRVSEDERDRVLEELHKAEDSLLAAEEAAAKAEADVASLNRRIQLVEEELDRA 102
I A ++ ++V + + D E + + + A +AEA+VASLNRRIQLVEEELDRA
Sbjct: 7 IEAVKRKIQVLQQQADDAEERAERLQREVEGERRAREQAEAEVASLNRRIQLVEEELDRA 66
Query: 103 QERLATALQKLEEAEKAADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKY 162
QERLATALQKLEEAEKAADESERGMKVIE+RA KDEEKME+QEIQLKEAKHIAE+ADRKY
Sbjct: 67 QERLATALQKLEEAEKAADESERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKY 126
Query: 163 EEVARKLVIIESDLERAEERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKEDRYE 222
EEVARKLVIIE DLER EERAEL+E +C E++E+++ + NLK L A EKYSQKED+YE
Sbjct: 127 EEVARKLVIIEGDLERTEERAELAESRCREMDEQIRLMDQNLKCLSAAEEKYSQKEDKYE 186
Query: 223 EEIKVLSDKLKEAETRAEFAERSVTKLEKSIDDLEEKVAHAKEENLSMHQMLDQTLLEL 281
EEIK+L+DKLKEAETRAEFAERSV KLEK+IDDLEE++ E N + L TL +L
Sbjct: 187 EEIKILTDKLKEAETRAEFAERSVAKLEKTIDDLEERLYSQLERNRLLSNELKLTLHDL 245
>gi|224922812 tropomyosin 2 (beta) isoform 3 [Homo sapiens]
Length = 231
Score = 280 bits (717), Expect = 8e-76
Identities = 161/284 (56%), Positives = 199/284 (70%), Gaps = 53/284 (18%)
Query: 1 MDAIKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEEDIAAKEKLLRVSEDERDRV 60
MDAIKKKMQMLKLDKENA+ DR++Q E D + ++R +
Sbjct: 1 MDAIKKKMQMLKLDKENAI--------------DRAEQAEAD--------KKQAEDRCKQ 38
Query: 61 LEELHKAEDSLLAAEEAAAKAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAA 120
LEE +A L ++++ E+E++ K E+EKAA
Sbjct: 39 LEEEQQA--------------------LQKKLKGTEDEVE-----------KYSESEKAA 67
Query: 121 DESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAE 180
DESERGMKVIE+RA KDEEKME+QE+QLKEAKHIAED+DRKYEEVARKLVI+E +LER+E
Sbjct: 68 DESERGMKVIENRAMKDEEKMELQEMQLKEAKHIAEDSDRKYEEVARKLVILEGELERSE 127
Query: 181 ERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKEDRYEEEIKVLSDKLKEAETRAE 240
ERAE++E + +LEEEL+T+ LKSL A E+YS KED+YEEEIK+L +KLKEAETRAE
Sbjct: 128 ERAEVAESRARQLEEELRTMDQALKSLMASEEEYSTKEDKYEEEIKLLEEKLKEAETRAE 187
Query: 241 FAERSVTKLEKSIDDLEEKVAHAKEENLSMHQMLDQTLLELNNM 284
FAERSV KLEK+IDDLEE +A AKEEN+ +HQ LDQTLLELNN+
Sbjct: 188 FAERSVAKLEKTIDDLEETLASAKEENVEIHQTLDQTLLELNNL 231
>gi|12667788 myosin, heavy polypeptide 9, non-muscle [Homo sapiens]
Length = 1960
Score = 90.9 bits (224), Expect = 1e-18
Identities = 70/277 (25%), Positives = 127/277 (45%), Gaps = 15/277 (5%)
Query: 6 KKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEEDIAAKEKLLRVSEDERDRVLEELH 65
+++ + +E L +A++ E K+ E QL+E++AA E+ R ++ ERD + +E+
Sbjct: 1652 RELDDTRASREEILAQAKENEKKLKSMEAEMIQLQEELAAAERAKRQAQQERDELADEIA 1711
Query: 66 KAEDSLLAAEEAAAKAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESER 125
+ A E + EA +A L EEEL+ Q +L++A D+
Sbjct: 1712 NSSGKGALALEEKRRLEARIAQL-------EEELEEEQGNTELINDRLKKANLQIDQINT 1764
Query: 126 GMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDAD----RKYEE----VARKLVIIESDLE 177
+ + S AQK+E + E Q KE K ++ + KY+ + K+ +E L+
Sbjct: 1765 DLNLERSHAQKNENARQQLERQNKELKVKLQEMEGTVKSKYKASITALEAKIAQLEEQLD 1824
Query: 178 RAEERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKEDRYEEEIKVLSDKLKEAET 237
+ + + + E++LK V + AE+Y + D+ +K L +L+EAE
Sbjct: 1825 NETKERQAACKQVRRTEKKLKDVLLQVDDERRNAEQYKDQADKASTRLKQLKRQLEEAEE 1884
Query: 238 RAEFAERSVTKLEKSIDDLEEKVAHAKEENLSMHQML 274
A+ A S KL++ ++D E E S+ L
Sbjct: 1885 EAQRANASRRKLQRELEDATETADAMNREVSSLKNKL 1921
Score = 71.6 bits (174), Expect = 7e-13
Identities = 72/298 (24%), Positives = 135/298 (45%), Gaps = 38/298 (12%)
Query: 7 KMQMLKLDKE--NALDRAEQAEADKKAA-------EDRSKQLEEDIAAK-------EKLL 50
KMQ+ K ++E AL R E+ A K A E + +L+ED+ ++ EK
Sbjct: 1075 KMQLAKKEEELQAALARVEEEAAQKNMALKKIRELESQISELQEDLESERASRNKAEKQK 1134
Query: 51 RVSEDERDRVLEELHKAEDSLLAAEEAAAKAEADVASLNR-----------RIQLVEEEL 99
R +E + + EL DS A +E +K E +V L + +IQ + ++
Sbjct: 1135 RDLGEELEALKTELEDTLDSTAAQQELRSKREQEVNILKKTLEEEAKTHEAQIQEMRQKH 1194
Query: 100 DRAQERLATALQKLE------EAEKAADESERG-----MKVIESRAQKDEEKMEIQEIQL 148
+A E LA L++ + E K E+ERG +KV+ E K + E QL
Sbjct: 1195 SQAVEELAEQLEQTKRVKANLEKAKQTLENERGELANEVKVLLQGKGDSEHKRKKVEAQL 1254
Query: 149 KEAKHIAEDADRKYEEVARKLVIIESDLERAEERAELSEGKCAELEEELKTVTNNLKSLE 208
+E + + +R E+A K+ ++ +L+ S+ K ++L ++ + + L+ +
Sbjct: 1255 QELQVKFNEGERVRTELADKVTKLQVELDNVTGLLSQSDSKSSKLTKDFSALESQLQDTQ 1314
Query: 209 AQAEKYSQKEDRYEEEIKVLSDKLKEAETRAEFAERSVTKLEKSIDDLEEKVAHAKEE 266
++ ++++ ++K + D+ + E E + LEK I L +VA K++
Sbjct: 1315 ELLQEENRQKLSLSTKLKQVEDEKNSFREQLEEEEEAKHNLEKQIATLHAQVADMKKK 1372
Score = 67.8 bits (164), Expect = 1e-11
Identities = 67/309 (21%), Positives = 142/309 (45%), Gaps = 32/309 (10%)
Query: 2 DAIKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEEDIAAKEKLLRVSEDERDRVL 61
D ++K L+ + ++ L + E + K+ ++ +A ++ + +ERDR
Sbjct: 1409 DKLEKTKTRLQQELDDLLVDLDHQRQSACNLEKKQKKFDQLLAEEKTISAKYAEERDRAE 1468
Query: 62 EELHKAED---SLLAAEEAAAKAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEK 118
E + E SL A E A + +A++ LN++ + E+L +++ + ++ +LE++++
Sbjct: 1469 AEAREKETKALSLARALEEAMEQKAELERLNKQFRTEMEDLMSSKDDVGKSVHELEKSKR 1528
Query: 119 AADESERGMKV----IESRAQKDEEKMEIQEIQLKEAK----HIAEDADRKYEEVARKLV 170
A ++ MK +E Q E+ E+ L+ K + D + EE ++LV
Sbjct: 1529 ALEQQVEEMKTQLEELEDELQATEDAKLRLEVNLQAMKAQFERDLQGRDEQSEEKKKQLV 1588
Query: 171 --IIESDLERAEERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKEDRYEEEIKVL 228
+ E + E +ER + S A + E+ +LK LEA + ++ D ++++ L
Sbjct: 1589 RQVREMEAELEDERKQRSMAVAARKKLEM-----DLKDLEAHIDSANKNRDEAIKQLRKL 1643
Query: 229 SDKLKEA-----ETR---------AEFAERSVTKLEKSIDDLEEKVAHAKEENLSMHQML 274
++K+ +TR A+ E+ + +E + L+E++A A+ Q
Sbjct: 1644 QAQMKDCMRELDDTRASREEILAQAKENEKKLKSMEAEMIQLQEELAAAERAKRQAQQER 1703
Query: 275 DQTLLELNN 283
D+ E+ N
Sbjct: 1704 DELADEIAN 1712
Score = 67.4 bits (163), Expect = 1e-11
Identities = 78/326 (23%), Positives = 147/326 (45%), Gaps = 46/326 (14%)
Query: 4 IKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEEDIAAKEKLLR--------VSED 55
++K + L+ E + E+ E + +A ED +LE ++ A + SE+
Sbjct: 1523 LEKSKRALEQQVEEMKTQLEELEDELQATEDAKLRLEVNLQAMKAQFERDLQGRDEQSEE 1582
Query: 56 ERDRVLEELHKAEDSL-------LAAEEAAAKAEADVASLNRRIQLVEEELDRAQERLAT 108
++ +++ ++ + E L A A K E D+ L I + D A ++L
Sbjct: 1583 KKKQLVRQVREMEAELEDERKQRSMAVAARKKLEMDLKDLEAHIDSANKNRDEAIKQLRK 1642
Query: 109 ALQKLEEAEKAADESERGMKVIESRAQKDEEK---MEIQEIQLKEAKHIAEDADRKYEEV 165
++++ + D++ + I ++A+++E+K ME + IQL+E AE A R+ ++
Sbjct: 1643 LQAQMKDCMRELDDTRASREEILAQAKENEKKLKSMEAEMIQLQEELAAAERAKRQAQQE 1702
Query: 166 ARKLV--IIESDLERA---EERAELSEGKCAELEEEL-------KTVTNNLKSLEAQ--- 210
+L I S + A EE+ L E + A+LEEEL + + + LK Q
Sbjct: 1703 RDELADEIANSSGKGALALEEKRRL-EARIAQLEEELEEEQGNTELINDRLKKANLQIDQ 1761
Query: 211 -----------AEKYSQKEDRYEEEIKVLSDKLKEAE-TRAEFAERSVTKLEKSIDDLEE 258
A+K + E + K L KL+E E T + S+T LE I LEE
Sbjct: 1762 INTDLNLERSHAQKNENARQQLERQNKELKVKLQEMEGTVKSKYKASITALEAKIAQLEE 1821
Query: 259 KVAHAKEENLSMHQMLDQTLLELNNM 284
++ + +E + + + +T +L ++
Sbjct: 1822 QLDNETKERQAACKQVRRTEKKLKDV 1847
Score = 66.6 bits (161), Expect = 2e-11
Identities = 60/260 (23%), Positives = 124/260 (47%), Gaps = 29/260 (11%)
Query: 36 SKQLEEDIAAKEKLLRVSEDERDRVLEELHKAEDSLLAAEEAAAKAEADVASLNRRIQLV 95
S+Q EE +A +E+L++V E + AE+ L E ++ A+ L ++Q
Sbjct: 841 SRQEEEMMAKEEELVKVREKQL--------AAENRLTEMETLQSQLMAEKLQLQEQLQAE 892
Query: 96 EEELDRAQERLATALQKLEEAEKAADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIA 155
E A+E A K +E E+ + +E+R +++EE+ + + + K+ +
Sbjct: 893 TELCAEAEELRARLTAKKQELEEICHD-------LEARVEEEEERCQHLQAEKKKMQQNI 945
Query: 156 EDADRKYEE---VARKL----VIIESDLERAEERAELSEGKCAELEEELKTV-------T 201
++ + + EE +KL V E+ L++ EE + E + +L +E K + T
Sbjct: 946 QELEEQLEEEESARQKLQLEKVTTEAKLKKLEEEQIILEDQNCKLAKEKKLLEDRIAEFT 1005
Query: 202 NNLKSLEAQAEKYSQKEDRYEEEIKVLSDKLKEAETRAEFAERSVTKLEKSIDDLEEKVA 261
NL E +++ ++ ++++E I L ++L+ E + + E++ KLE DL +++A
Sbjct: 1006 TNLTEEEEKSKSLAKLKNKHEAMITDLEERLRREEKQRQELEKTRRKLEGDSTDLSDQIA 1065
Query: 262 HAKEENLSMHQMLDQTLLEL 281
+ + + L + EL
Sbjct: 1066 ELQAQIAELKMQLAKKEEEL 1085
Score = 66.2 bits (160), Expect = 3e-11
Identities = 79/292 (27%), Positives = 129/292 (44%), Gaps = 40/292 (13%)
Query: 4 IKKKMQMLKLDKENALDRAEQAEAD-KKAAEDRSKQLEEDIAAKEKLLRVS---EDERDR 59
+KKKM+ D L+ AE+ + +K E S++ EE +AA +KL + + E D
Sbjct: 1369 MKKKME----DSVGCLETAEEVKRKLQKDLEGLSQRHEEKVAAYDKLEKTKTRLQQELDD 1424
Query: 60 VLEELHKAEDSLLAAEEAAAKAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKA 119
+L +L S E+ K + +A EE DRA+ A A +K +A
Sbjct: 1425 LLVDLDHQRQSACNLEKKQKKFDQLLAEEKTISAKYAEERDRAE---AEAREKETKALSL 1481
Query: 120 ADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERA 179
A E M E+K E++ + K+ + ED ++V + + +E
Sbjct: 1482 ARALEEAM----------EQKAELERLN-KQFRTEMEDLMSSKDDVGKSVHELEKSKRAL 1530
Query: 180 EERAELSEGKCAELEEELKTVTN-------NLKSLEAQAEKYSQKEDRYEEEIK---VLS 229
E++ E + + ELE+EL+ + NL++++AQ E+ Q D EE K V
Sbjct: 1531 EQQVEEMKTQLEELEDELQATEDAKLRLEVNLQAMKAQFERDLQGRDEQSEEKKKQLVRQ 1590
Query: 230 DKLKEAETRAEFAERSVT-----KLEKSIDDLEEKVAHAKEENLSMHQMLDQ 276
+ EAE E +RS+ KLE + DLE AH N + + + Q
Sbjct: 1591 VREMEAELEDERKQRSMAVAARKKLEMDLKDLE---AHIDSANKNRDEAIKQ 1639
Score = 63.9 bits (154), Expect = 2e-10
Identities = 68/327 (20%), Positives = 139/327 (42%), Gaps = 49/327 (14%)
Query: 1 MDAIKKKMQMLKLDKENALDRAEQA----EADKKAAEDRSKQLEED----------IAAK 46
+ A KKKMQ + E L+ E A + +K E + K+LEE+ +A +
Sbjct: 934 LQAEKKKMQQNIQELEEQLEEEESARQKLQLEKVTTEAKLKKLEEEQIILEDQNCKLAKE 993
Query: 47 EKLLR----------VSEDERDRVLEELHKAEDSLLA---------------AEEAAAKA 81
+KLL E+E+ + L +L ++++ E+ K
Sbjct: 994 KKLLEDRIAEFTTNLTEEEEKSKSLAKLKNKHEAMITDLEERLRREEKQRQELEKTRRKL 1053
Query: 82 EAD-------VASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIESRA 134
E D +A L +I ++ +L + +E L AL ++EE + + + ++ +ES+
Sbjct: 1054 EGDSTDLSDQIAELQAQIAELKMQLAKKEEELQAALARVEEEAAQKNMALKKIRELESQI 1113
Query: 135 QKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAEERAELSEGKCAELE 194
+ +E +E + +A+ D + E + +L E L+ + EL + E+
Sbjct: 1114 SELQEDLESERASRNKAEKQKRDLGEELEALKTEL---EDTLDSTAAQQELRSKREQEVN 1170
Query: 195 EELKTVTNNLKSLEAQAEKYSQKEDRYEEEIKVLSDKLKEAETRAEFAERSVTKLEKSID 254
KT+ K+ EAQ ++ QK + EE+ ++ K + E A++++ +
Sbjct: 1171 ILKKTLEEEAKTHEAQIQEMRQKHSQAVEELAEQLEQTKRVKANLEKAKQTLENERGELA 1230
Query: 255 DLEEKVAHAKEENLSMHQMLDQTLLEL 281
+ + + K ++ + ++ L EL
Sbjct: 1231 NEVKVLLQGKGDSEHKRKKVEAQLQEL 1257
Score = 62.8 bits (151), Expect = 3e-10
Identities = 62/271 (22%), Positives = 128/271 (47%), Gaps = 27/271 (9%)
Query: 7 KMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEEDIAAKEKLLRVSEDERDRV------ 60
K++ +L EN L E ++ A + QL+E + A+ +L +E+ R R+
Sbjct: 856 KVREKQLAAENRLTEMETLQSQLMAEK---LQLQEQLQAETELCAEAEELRARLTAKKQE 912
Query: 61 LEEL-HKAEDSLLAAEEAAAKAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKA 119
LEE+ H E + EE +A+ + + IQ +EE+L+ + +A QKL + EK
Sbjct: 913 LEEICHDLEARVEEEEERCQHLQAEKKKMQQNIQELEEQLEEEE----SARQKL-QLEKV 967
Query: 120 ADES-----ERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVAR------- 167
E+ E ++E + K ++ ++ E ++ E + + K + +A+
Sbjct: 968 TTEAKLKKLEEEQIILEDQNCKLAKEKKLLEDRIAEFTTNLTEEEEKSKSLAKLKNKHEA 1027
Query: 168 KLVIIESDLERAEERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKEDRYEEEIKV 227
+ +E L R E++ + E +LE + +++ + L+AQ + + + EEE++
Sbjct: 1028 MITDLEERLRREEKQRQELEKTRRKLEGDSTDLSDQIAELQAQIAELKMQLAKKEEELQA 1087
Query: 228 LSDKLKEAETRAEFAERSVTKLEKSIDDLEE 258
+++E + A + + +LE I +L+E
Sbjct: 1088 ALARVEEEAAQKNMALKKIRELESQISELQE 1118
Score = 61.2 bits (147), Expect = 1e-09
Identities = 67/307 (21%), Positives = 129/307 (42%), Gaps = 39/307 (12%)
Query: 16 ENALDRAEQAEADKKAAEDRSKQLEEDIAAKEKLLRVSEDERDRVLEELHKAEDSLLAAE 75
E +R + +A+KK + ++LEE + +E + + E+ +L K E+ + E
Sbjct: 925 EEEEERCQHLQAEKKKMQQNIQELEEQLEEEESARQKLQLEKVTTEAKLKKLEEEQIILE 984
Query: 76 EAAAKAEADVASLNRRI-----QLVEEE----------------LDRAQERLATALQKLE 114
+ K + L RI L EEE + +ERL ++ +
Sbjct: 985 DQNCKLAKEKKLLEDRIAEFTTNLTEEEEKSKSLAKLKNKHEAMITDLEERLRREEKQRQ 1044
Query: 115 EAEKA-----ADESERGMKVIESRAQKDEEKMEI----QEIQLKEAKHIAEDAD-----R 160
E EK D ++ ++ E +AQ E KM++ +E+Q A+ E A +
Sbjct: 1045 ELEKTRRKLEGDSTDLSDQIAELQAQIAELKMQLAKKEEELQAALARVEEEAAQKNMALK 1104
Query: 161 KYEEVARKLVIIESDLERAEERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKEDR 220
K E+ ++ ++ DLE +E + +L EEL+ + L+ + +
Sbjct: 1105 KIRELESQISELQEDLESERASRNKAEKQKRDLGEELEALKTELEDTLDSTAAQQELRSK 1164
Query: 221 YEEEIKVLSDKL-KEAETRAEFAERSVTKLEKSIDDLEEKVAHAKEENLSMH---QMLDQ 276
E+E+ +L L +EA+T + K +++++L E++ K ++ Q L+
Sbjct: 1165 REQEVNILKKTLEEEAKTHEAQIQEMRQKHSQAVEELAEQLEQTKRVKANLEKAKQTLEN 1224
Query: 277 TLLELNN 283
EL N
Sbjct: 1225 ERGELAN 1231
Score = 58.5 bits (140), Expect = 6e-09
Identities = 62/271 (22%), Positives = 122/271 (45%), Gaps = 20/271 (7%)
Query: 23 EQAEADKKAAEDRSKQLEEDIAAK---EKLLRVSEDERDRVLEELHKAEDSLLAAEEAAA 79
E + +A E+ ++QLE+ K EK + E+ER + E+ +E
Sbjct: 1189 EMRQKHSQAVEELAEQLEQTKRVKANLEKAKQTLENERGELANEVKVLLQGKGDSEHKRK 1248
Query: 80 KAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIESRAQKDEE 139
K EA + L Q+ E +R + LA + KL+ D + +S++ K +
Sbjct: 1249 KVEAQLQEL----QVKFNEGERVRTELADKVTKLQVE---LDNVTGLLSQSDSKSSKLTK 1301
Query: 140 KMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAEERAELSEGKCAELEEELKT 199
E QL++ + + ++ +R+ ++ KL +E + E+ E E LE+++ T
Sbjct: 1302 DFSALESQLQDTQELLQEENRQKLSLSTKLKQVEDEKNSFREQLEEEEEAKHNLEKQIAT 1361
Query: 200 ----VTNNLKSLEAQA---EKYSQKEDRYEEEIKVLSDKLKEAETRAEFAERSVTKLEKS 252
V + K +E E + + + +++++ LS + +E + E++ T+L++
Sbjct: 1362 LHAQVADMKKKMEDSVGCLETAEEVKRKLQKDLEGLSQRHEEKVAAYDKLEKTKTRLQQE 1421
Query: 253 IDDLEEKVAHAKEE--NLSMHQ-MLDQTLLE 280
+DDL + H ++ NL Q DQ L E
Sbjct: 1422 LDDLLVDLDHQRQSACNLEKKQKKFDQLLAE 1452
Score = 51.2 bits (121), Expect = 1e-06
Identities = 49/252 (19%), Positives = 111/252 (44%), Gaps = 18/252 (7%)
Query: 33 EDRSKQLEEDIAAKEKL---LRVSEDERDRVLEELHKAEDSLLAAEEAAAKAEADVASLN 89
+D + L+E+ K L L+ EDE++ E+L + E++ E+ A A VA +
Sbjct: 1311 QDTQELLQEENRQKLSLSTKLKQVEDEKNSFREQLEEEEEAKHNLEKQIATLHAQVADMK 1370
Query: 90 RR-------IQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIESRAQKDEEKME 142
++ ++ EE + Q+ L Q+ EE A D+ E+ ++R Q++ + +
Sbjct: 1371 KKMEDSVGCLETAEEVKRKLQKDLEGLSQRHEEKVAAYDKLEK----TKTRLQQELDDLL 1426
Query: 143 IQEIQLKEAKHIAEDADRKYEEVARKLVIIES----DLERAEERAELSEGKCAELEEELK 198
+ +++ E +K++++ + I + + +RAE A E K L L+
Sbjct: 1427 VDLDHQRQSACNLEKKQKKFDQLLAEEKTISAKYAEERDRAEAEAREKETKALSLARALE 1486
Query: 199 TVTNNLKSLEAQAEKYSQKEDRYEEEIKVLSDKLKEAETRAEFAERSVTKLEKSIDDLEE 258
LE +++ + + + + E E E+ V +++ +++LE+
Sbjct: 1487 EAMEQKAELERLNKQFRTEMEDLMSSKDDVGKSVHELEKSKRALEQQVEEMKTQLEELED 1546
Query: 259 KVAHAKEENLSM 270
++ ++ L +
Sbjct: 1547 ELQATEDAKLRL 1558
Score = 50.1 bits (118), Expect = 2e-06
Identities = 58/273 (21%), Positives = 108/273 (39%), Gaps = 19/273 (6%)
Query: 25 AEADKKAAEDRSKQLEEDIAAKEKLLRVSEDERDRVLEELHKAEDSLLAAEEAAAKAEAD 84
+E +K E + ++L+ E++ D+ ++ EL L ++ ++K D
Sbjct: 1243 SEHKRKKVEAQLQELQVKFNEGERVRTELADKVTKLQVELDNVTGLLSQSDSKSSKLTKD 1302
Query: 85 VASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIESRAQKDEEKMEIQ 144
++L ++Q +E L + + KL++ E + ++ E E+++
Sbjct: 1303 FSALESQLQDTQELLQEENRQKLSLSTKLKQVEDEKNSFREQLEEEEEAKHNLEKQIATL 1362
Query: 145 EIQLKEAKHIAEDAD---RKYEEVARKLVIIESDLERAEERAELSEGKCAELEEELKTVT 201
Q+ + K ED+ EEV RKL + DLE +R E +LE+ +
Sbjct: 1363 HAQVADMKKKMEDSVGCLETAEEVKRKL---QKDLEGLSQRHEEKVAAYDKLEKTKTRLQ 1419
Query: 202 NNLKSL----------EAQAEKYSQKEDRYEEEIKVLSDKLKEAETRAEFAERSVTKLEK 251
L L EK +K D+ E K +S K E RAE R + E
Sbjct: 1420 QELDDLLVDLDHQRQSACNLEKKQKKFDQLLAEEKTISAKYAEERDRAEAEAR---EKET 1476
Query: 252 SIDDLEEKVAHAKEENLSMHQMLDQTLLELNNM 284
L + A E+ + ++ Q E+ ++
Sbjct: 1477 KALSLARALEEAMEQKAELERLNKQFRTEMEDL 1509
Score = 38.5 bits (88), Expect = 0.007
Identities = 36/146 (24%), Positives = 64/146 (43%), Gaps = 14/146 (9%)
Query: 7 KMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEEDIAAKEKLLRVSEDERDRVLEELHK 66
+ Q+ + +KE + E K + LE IA E+ L ER +++ +
Sbjct: 1780 RQQLERQNKELKVKLQEMEGTVKSKYKASITALEAKIAQLEEQLDNETKERQAACKQVRR 1839
Query: 67 AE----DSLLAAEEAAAKAE-----ADVAS-----LNRRIQLVEEELDRAQERLATALQK 112
E D LL ++ AE AD AS L R+++ EEE RA ++
Sbjct: 1840 TEKKLKDVLLQVDDERRNAEQYKDQADKASTRLKQLKRQLEEAEEEAQRANASRRKLQRE 1899
Query: 113 LEEAEKAADESERGMKVIESRAQKDE 138
LE+A + AD R + ++++ ++ +
Sbjct: 1900 LEDATETADAMNREVSSLKNKLRRGD 1925
Score = 30.8 bits (68), Expect = 1.4
Identities = 22/107 (20%), Positives = 46/107 (42%), Gaps = 2/107 (1%)
Query: 176 LERAEERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKEDRYEEEIKVLSDKLKEA 235
+ R EE E + ++ E+ N L +E + ++ + +E+++ ++ EA
Sbjct: 840 VSRQEEEMMAKEEELVKVREKQLAAENRLTEMETLQSQLMAEKLQLQEQLQAETELCAEA 899
Query: 236 ETRAEFAERSVTKLEKSIDDLEEKVAHAKEENLSMHQMLDQTLLELN 282
E +LE+ DLE +V +EE H ++ ++ N
Sbjct: 900 EELRARLTAKKQELEEICHDLEARV--EEEEERCQHLQAEKKKMQQN 944
Score = 29.3 bits (64), Expect = 4.1
Identities = 23/89 (25%), Positives = 40/89 (44%), Gaps = 7/89 (7%)
Query: 5 KKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEEDIAAKEKLLRVSEDERDRVLEEL 64
+KK++ + L ++ AEQ + A R KQL ++ L +E+E R
Sbjct: 1841 EKKLKDVLLQVDDERRNAEQYKDQADKASTRLKQL-------KRQLEEAEEEAQRANASR 1893
Query: 65 HKAEDSLLAAEEAAAKAEADVASLNRRIQ 93
K + L A E A +V+SL +++
Sbjct: 1894 RKLQRELEDATETADAMNREVSSLKNKLR 1922
>gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo
sapiens]
Length = 570
Score = 85.5 bits (210), Expect = 5e-17
Identities = 56/255 (21%), Positives = 123/255 (48%), Gaps = 6/255 (2%)
Query: 6 KKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEEDIAAKEKLLRVSEDERDRVLEELH 65
++ + + +KE + R E+ +K E++ ++LEE + +EK + E E R EE
Sbjct: 319 RRQEEMMWEKEEKMRRQEEMMWEK---EEKIRELEEKMHEQEK---IREQEEKRQEEEKI 372
Query: 66 KAEDSLLAAEEAAAKAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESER 125
+ ++ E + E + +I+ EE + +E++ +K+ E E+ E E
Sbjct: 373 REQEKRQEQEAKMWRQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMWEQEEEMQEQEE 432
Query: 126 GMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAEERAEL 185
M+ E + ++ E+K+ QE +++E + + ++ + K E K+ E+ ++ EE+
Sbjct: 433 KMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMGEQEGKMCEQEAKMQEQEEKMRR 492
Query: 186 SEGKCAELEEELKTVTNNLKSLEAQAEKYSQKEDRYEEEIKVLSDKLKEAETRAEFAERS 245
E K E E++++ ++ E ++ +K EE++ +K++E E + E
Sbjct: 493 QEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEK 552
Query: 246 VTKLEKSIDDLEEKV 260
+ + E + EEK+
Sbjct: 553 MREQEVRLRQQEEKM 567
Score = 80.1 bits (196), Expect = 2e-15
Identities = 57/253 (22%), Positives = 121/253 (47%), Gaps = 8/253 (3%)
Query: 20 DRAEQAEADKKAAEDRSKQLEEDIAAKEKLLRVSED------ERDRVLEELHKAEDSLLA 73
++ ++ E + E++ ++ EE + KE+ +R E+ E+ R LEE ++ +
Sbjct: 302 EKIQEQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIRE 361
Query: 74 AEEAAAKAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIESR 133
EE + E R+ Q E ++ R +E++ +K+ E E+ E E M E +
Sbjct: 362 QEEKRQEEEKIREQEKRQEQ--EAKMWRQEEKIREQEEKIREQEEMMQEQEEKMGEQEEK 419
Query: 134 AQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAEERAELSEGKCAEL 193
+ EE+M+ QE +++ + + ++K E K+ E ++ EE+ EGK E
Sbjct: 420 MWEQEEEMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMGEQEGKMCEQ 479
Query: 194 EEELKTVTNNLKSLEAQAEKYSQKEDRYEEEIKVLSDKLKEAETRAEFAERSVTKLEKSI 253
E +++ ++ E + + +K EE+I+ + ++E E + E + + E+ +
Sbjct: 480 EAKMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKM 539
Query: 254 DDLEEKVAHAKEE 266
+ EEK+ +E+
Sbjct: 540 QEQEEKMRRQEEK 552
Score = 79.0 bits (193), Expect = 5e-15
Identities = 67/281 (23%), Positives = 131/281 (46%), Gaps = 19/281 (6%)
Query: 1 MDAIKKKMQMLKLDKENALDRAEQAEADKK-AAEDRSKQLEEDIAAKEKLLRVSEDERDR 59
+ ++ K+Q ++++ +R Q + +K E++ ++ EE I +E+ +R E++ R
Sbjct: 262 LQSVSAKLQA-QVEENELWNRLNQQQEEKMWRQEEKIQEREEKIQEQEEKIREQEEKMRR 320
Query: 60 VLEELHKAEDSLLAAEEAAAKAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKA 119
E + + E+ + EE + E + L ++ E+E R QE +K+ E EK
Sbjct: 321 QEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMH--EQEKIREQEEKRQEEEKIREQEKR 378
Query: 120 ADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERA 179
E E M E + ++ EEK+ QE ++E + + + K E ++ E + R
Sbjct: 379 -QEQEAKMWRQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMWEQEEEMQEQEEKMRRQ 437
Query: 180 EERAELSEGKCAELEEELKTVTNNL------------KSLEAQAEKYSQKED--RYEEEI 225
EE+ E K E EE+++ + K E +A+ Q+E R EE+I
Sbjct: 438 EEKIREQEKKIREQEEKIREQEEMMQEQEEKMGEQEGKMCEQEAKMQEQEEKMRRQEEKI 497
Query: 226 KVLSDKLKEAETRAEFAERSVTKLEKSIDDLEEKVAHAKEE 266
+ K++E E + E + + E+ + + EEK+ +E+
Sbjct: 498 REQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEK 538
Score = 75.1 bits (183), Expect = 7e-14
Identities = 50/239 (20%), Positives = 110/239 (46%)
Query: 2 DAIKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEEDIAAKEKLLRVSEDERDRVL 61
+ ++++ +M+ +E + E+ +K E K+ EE+ +++ + E + R
Sbjct: 330 EKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQE 389
Query: 62 EELHKAEDSLLAAEEAAAKAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAAD 121
E++ + E+ + EE + E + ++ EEE+ +E++ +K+ E EK
Sbjct: 390 EKIREQEEKIREQEEMMQEQEEKMGEQEEKMWEQEEEMQEQEEKMRRQEEKIREQEKKIR 449
Query: 122 ESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAEE 181
E E ++ E Q+ EEKM QE ++ E + ++ + K K+ E + EE
Sbjct: 450 EQEEKIREQEEMMQEQEEKMGEQEGKMCEQEAKMQEQEEKMRRQEEKIREQEKKIREQEE 509
Query: 182 RAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKEDRYEEEIKVLSDKLKEAETRAE 240
+ E E EE++ + E + ++ +K R EE+++ +L++ E + +
Sbjct: 510 KIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMREQEVRLRQQEEKMQ 568
Score = 72.4 bits (176), Expect = 4e-13
Identities = 62/279 (22%), Positives = 134/279 (48%), Gaps = 16/279 (5%)
Query: 1 MDAIKKKMQMLKLDKENALDRAE--------QAEADK--KAAEDRSKQLEEDIAAKEKLL 50
+++ K ++Q+ + + L+RA+ QAEAD K + S +L+ + E
Sbjct: 221 VESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEENELWN 280
Query: 51 RVSEDERDRVL---EELHKAEDSLLAAEEAAAKAEADVASLNRRIQLVEEELDRAQERLA 107
R+++ + +++ E++ + E+ + EE + E + + EE++ R +E +
Sbjct: 281 RLNQQQEEKMWRQEEKIQEREEKIQEQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMW 340
Query: 108 TALQKLEEAEKAADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVAR 167
+K+ E E+ E E+ ++ E + Q++E+ E ++ Q +EAK ++ K E
Sbjct: 341 EKEEKIRELEEKMHEQEK-IREQEEKRQEEEKIREQEKRQEQEAKMWRQE--EKIREQEE 397
Query: 168 KLVIIESDLERAEERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKEDRYEEEIKV 227
K+ E ++ EE+ E K E EEE++ ++ E + + +K EE+I+
Sbjct: 398 KIREQEEMMQEQEEKMGEQEEKMWEQEEEMQEQEEKMRRQEEKIREQEKKIREQEEKIRE 457
Query: 228 LSDKLKEAETRAEFAERSVTKLEKSIDDLEEKVAHAKEE 266
+ ++E E + E + + E + + EEK+ +E+
Sbjct: 458 QEEMMQEQEEKMGEQEGKMCEQEAKMQEQEEKMRRQEEK 496
Score = 69.7 bits (169), Expect = 3e-12
Identities = 42/201 (20%), Positives = 98/201 (48%)
Query: 14 DKENALDRAEQAEADKKAAEDRSKQLEEDIAAKEKLLRVSEDERDRVLEELHKAEDSLLA 73
+K ++ ++ EA E++ ++ EE I +E++++ E++ E++ + E+ +
Sbjct: 370 EKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMWEQEEEMQE 429
Query: 74 AEEAAAKAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIESR 133
EE + E + ++I+ EE++ +E + +K+ E E E E M+ E +
Sbjct: 430 QEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMGEQEGKMCEQEAKMQEQEEK 489
Query: 134 AQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAEERAELSEGKCAEL 193
++ EEK+ QE +++E + + + +E K+ E + EE+ + E K
Sbjct: 490 MRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQ 549
Query: 194 EEELKTVTNNLKSLEAQAEKY 214
EE+++ L+ E + +++
Sbjct: 550 EEKMREQEVRLRQQEEKMQEH 570
Score = 63.2 bits (152), Expect = 3e-10
Identities = 70/304 (23%), Positives = 127/304 (41%), Gaps = 46/304 (15%)
Query: 5 KKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEEDIAAKEKLLRVSEDERDRVLEEL 64
K ++QM ++A+ + E D + S + ++ + + + DR +EEL
Sbjct: 127 KTELQMALYYSQHAVKQLEGEARDLISRLHDSWKFAGELEQALSAVATQKKKADRYIEEL 186
Query: 65 HKAEDSL--------LAAEEAAAKAEADVASLNRRIQLVEEELDRAQERLATALQKLEEA 116
K D+L + EE K A L ++QLVE E Q + +KLE A
Sbjct: 187 TKERDALSLELYRNTITDEELKEKN----AKLQEKLQLVESEKSEIQLNVKELKRKLERA 242
Query: 117 ---------EKAADESERGMKVIESRAQ--------------KDEEKMEIQEIQLKEAKH 153
+ AD + ++ + ++ Q + EEKM QE +++E +
Sbjct: 243 KLLLPQQQLQAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEREE 302
Query: 154 IAEDADRKYEEVARKLVIIES-------DLERAEERAELSEGKCAELEEEL--KTVTNNL 204
++ + K E K+ E + R EE E K ELEE++ +
Sbjct: 303 KIQEQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQ 362
Query: 205 KSLEAQAEKYSQKEDRYEEEIKV--LSDKLKEAETRAEFAERSVTKLEKSIDDLEEKVAH 262
+ + EK ++E R E+E K+ +K++E E + E + + E+ + + EEK+
Sbjct: 363 EEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMWE 422
Query: 263 AKEE 266
+EE
Sbjct: 423 QEEE 426
>gi|239745079 PREDICTED: Putative golgin subfamily A member 6-like
protein 6 [Homo sapiens]
Length = 724
Score = 82.8 bits (203), Expect = 3e-16
Identities = 52/255 (20%), Positives = 124/255 (48%), Gaps = 3/255 (1%)
Query: 14 DKENALDRAEQAEADKKAAEDRSKQLEEDIAAKEKLLRVSED---ERDRVLEELHKAEDS 70
+K ++ ++ EA E++ ++ EE I +E+ + E+ E++++ EE + E
Sbjct: 464 EKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEEKMWRQEEKIHEQEKIREEEKRQEQE 523
Query: 71 LLAAEEAAAKAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVI 130
+ +E + + ++ +I EE++ + +E++ +K+ + E+ E E +
Sbjct: 524 EMWRQEEKIREQEEIWRQKEKIHEQEEKIRKQEEKMWRQEEKMHDQEEKIREQEEKVWRQ 583
Query: 131 ESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAEERAELSEGKC 190
E + ++ EEK+ QE +++E + + ++ + K E K+ E ++ EE+ E K
Sbjct: 584 EEKIREQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEEKMRRQEEKI 643
Query: 191 AELEEELKTVTNNLKSLEAQAEKYSQKEDRYEEEIKVLSDKLKEAETRAEFAERSVTKLE 250
E E++++ ++ E ++ +K EE++ +K++E E + E + + E
Sbjct: 644 REQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQE 703
Query: 251 KSIDDLEEKVAHAKE 265
+ EEK+ +E
Sbjct: 704 VRLRQQEEKMQEHQE 718
Score = 77.8 bits (190), Expect = 1e-14
Identities = 53/241 (21%), Positives = 116/241 (48%), Gaps = 1/241 (0%)
Query: 2 DAIKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEEDIAAKEKLLRVSEDERDRVL 61
+ I+++ + ++ +E + E+ +K E+ +Q +E++ +E+ +R ++E R
Sbjct: 484 EKIREQEEKIREQEEKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIR-EQEEIWRQK 542
Query: 62 EELHKAEDSLLAAEEAAAKAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAAD 121
E++H+ E+ + EE + E + +I+ EE++ R +E++ +K+ E E+
Sbjct: 543 EKIHEQEEKIRKQEEKMWRQEEKMHDQEEKIREQEEKVWRQEEKIREQEEKIREQEEKIR 602
Query: 122 ESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAEE 181
E E + E + + EEKM QE +++E + + K E +K+ E + EE
Sbjct: 603 EQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEE 662
Query: 182 RAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKEDRYEEEIKVLSDKLKEAETRAEF 241
+ E K E EE++ ++ E + + +K E ++ +K++E + E
Sbjct: 663 MMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQEEKMQEHQEHLEA 722
Query: 242 A 242
A
Sbjct: 723 A 723
Score = 74.7 bits (182), Expect = 9e-14
Identities = 60/282 (21%), Positives = 126/282 (44%), Gaps = 18/282 (6%)
Query: 6 KKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEEDIAAKEKLLRVSEDERDRVLEELH 65
++ + + +KE + R E+ +K E++ ++LEE + +EK + E E R EE
Sbjct: 413 RRQEEMMWEKEEKMRRQEEMMWEK---EEKIRELEEKMHEQEK---IREQEEKRQEEEKI 466
Query: 66 KAEDSLLAAEEAAAKAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESER 125
+ ++ E + E + +I+ EE++ R +E++ +K+ E EK ++ E
Sbjct: 467 REQEKRQEQEAKMWRQEEKIREQEEKIREQEEKMWRQEEKIHEQ-EKIREEEKRQEQEEM 525
Query: 126 GMKVIESRAQKD-----------EEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIES 174
+ + R Q++ EEK+ QE ++ + D + K E K+ E
Sbjct: 526 WRQEEKIREQEEIWRQKEKIHEQEEKIRKQEEKMWRQEEKMHDQEEKIREQEEKVWRQEE 585
Query: 175 DLERAEERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKEDRYEEEIKVLSDKLKE 234
+ EE+ E K E EE + + E + + +K EE+++ +K++E
Sbjct: 586 KIREQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEEKMRRQEEKIRE 645
Query: 235 AETRAEFAERSVTKLEKSIDDLEEKVAHAKEENLSMHQMLDQ 276
E + E + + E+ + + EEK+ +E+ + + +
Sbjct: 646 QEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQE 687
Score = 69.7 bits (169), Expect = 3e-12
Identities = 58/261 (22%), Positives = 115/261 (44%), Gaps = 19/261 (7%)
Query: 14 DKENALDRAEQAEADKKAAEDRSKQ--------LEEDIAAKEKLLRVSEDERDRVLEELH 65
++E ++ E+ + ++K E +Q EE I +E+ +R E++ R E++H
Sbjct: 449 EQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEEKMWRQEEKIH 508
Query: 66 KAEDSLLAAEEAAAKAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESER 125
+ E + EE + E +EE R QE + +K+ E E+ + E
Sbjct: 509 EQEK--IREEEKRQEQEE---------MWRQEEKIREQEEIWRQKEKIHEQEEKIRKQEE 557
Query: 126 GMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAEERAEL 185
M E + EEK+ QE ++ + + + K E K+ E + EE+
Sbjct: 558 KMWRQEEKMHDQEEKIREQEEKVWRQEEKIREQEEKIREQEEKIREQEEMTQEQEEKMGE 617
Query: 186 SEGKCAELEEELKTVTNNLKSLEAQAEKYSQKEDRYEEEIKVLSDKLKEAETRAEFAERS 245
E K E EE+++ ++ E + + +K EE+I+ + ++E E + E
Sbjct: 618 QEEKMCEQEEKMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEK 677
Query: 246 VTKLEKSIDDLEEKVAHAKEE 266
+ + E+ + + EEK+ +E+
Sbjct: 678 MCEQEEKMQEQEEKMRRQEEK 698
Score = 62.4 bits (150), Expect = 4e-10
Identities = 65/290 (22%), Positives = 127/290 (43%), Gaps = 28/290 (9%)
Query: 1 MDAIKKKMQMLKLDKENALDRAE--------QAEADK--KAAEDRSKQLEEDIAAKEKLL 50
+++ K ++Q+ + + L+RA+ QAEAD K + S +L+ + E
Sbjct: 294 VESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEENELWN 353
Query: 51 RVSEDERDRVLEELHKAEDSLLAAEEAAAKAEADVASLNRRIQLVEEELDRAQERLATAL 110
R+++ + E++ + E+ + EE + E + +I+ EE++ R +E +
Sbjct: 354 RLNQQQE----EKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKE 409
Query: 111 QKLEEAEKAADESERGMKVIESRAQKDEEK-----------MEIQEIQLKEAKHIAEDAD 159
+K+ E+ E E M+ E + EEK +I+E + K +
Sbjct: 410 EKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQ 469
Query: 160 RKYEEVARKLVIIESDLERAEERAELSEGKCAELEEEL--KTVTNNLKSLEAQAEKYSQK 217
K +E K+ E + EE+ E K EE++ + + + Q E + Q+
Sbjct: 470 EKRQEQEAKMWRQEEKIREQEEKIREQEEKMWRQEEKIHEQEKIREEEKRQEQEEMWRQE 529
Query: 218 ED-RYEEEIKVLSDKLKEAETRAEFAERSVTKLEKSIDDLEEKVAHAKEE 266
E R +EEI +K+ E E + E + + E+ + D EEK+ +E+
Sbjct: 530 EKIREQEEIWRQKEKIHEQEEKIRKQEEKMWRQEEKMHDQEEKIREQEEK 579
Score = 57.0 bits (136), Expect = 2e-08
Identities = 61/277 (22%), Positives = 124/277 (44%), Gaps = 23/277 (8%)
Query: 12 KLDKENAL--DRAEQAEADKKAAEDRSKQLEEDIAAKEKLL--RVSEDERDRVLEELHKA 67
+L ++NA ++ + E++K + K+L+ + + LL + + E D + +EL
Sbjct: 279 ELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSV 338
Query: 68 EDSLLAAEEAAA-------KAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAA 120
L A E + E + +IQ EE++ +E++ +K+ E E+
Sbjct: 339 SAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKM 398
Query: 121 DESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKL----VIIESDL 176
E M E + ++ EE M +E +++ + + + + K E+ K+ I E +
Sbjct: 399 RRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEE 458
Query: 177 ERAEERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKEDRYEEEIKVLSDKLKEAE 236
+R EE + K E E ++ ++ E + + +K R EE+I +K++E E
Sbjct: 459 KRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEEKMWRQEEKIHE-QEKIREEE 517
Query: 237 TRAEFAERSVTKLEKSIDDLEE-----KVAHAKEENL 268
R E + + + E+ I + EE + H +EE +
Sbjct: 518 KRQE--QEEMWRQEEKIREQEEIWRQKEKIHEQEEKI 552
Score = 55.1 bits (131), Expect = 7e-08
Identities = 59/280 (21%), Positives = 116/280 (41%), Gaps = 31/280 (11%)
Query: 5 KKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEEDIAAKEKLLRVSEDERDRVLEEL 64
K ++QM ++A+ + E D + S + ++ + + + DR +EEL
Sbjct: 200 KTELQMALYYSQHAVKQLEGEARDLISRLHDSWKFAGELEQALSAVATQKKKADRYIEEL 259
Query: 65 HKAEDSL--------LAAEEAAAKAEADVASLNRRIQLVEEELDRAQERLATALQKLEEA 116
K D+L + EE K A L ++QLVE E Q + +KLE A
Sbjct: 260 TKERDALSLELYRNTITDEELKEKN----AKLQEKLQLVESEKSEIQLNVKELKRKLERA 315
Query: 117 EKAADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDL 176
+ + + +A+ D E+Q + K + E+ E+ +L
Sbjct: 316 KLLLPQQQL-------QAEADHLGKELQSVSAKLQAQVEEN------ELWNRLN------ 356
Query: 177 ERAEERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKEDRYEEEIKVLSDKLKEAE 236
++ EE+ E K E EE+++ ++ E + + +K R EE + +K++ E
Sbjct: 357 QQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQE 416
Query: 237 TRAEFAERSVTKLEKSIDDLEEKVAHAKEENLSMHQMLDQ 276
E + + E+ + + EEK+ +E+ ++ +Q
Sbjct: 417 EMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQ 456
>gi|13124879 smooth muscle myosin heavy chain 11 isoform SM1A [Homo
sapiens]
Length = 1972
Score = 82.8 bits (203), Expect = 3e-16
Identities = 58/266 (21%), Positives = 130/266 (48%), Gaps = 15/266 (5%)
Query: 1 MDAIKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEEDIAAKEKLLRVSEDERDRV 60
M +++++ + ++ A++ E K+ E QL+ED+AA E+ + ++ E++ +
Sbjct: 1654 MKDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAERARKQADLEKEEL 1713
Query: 61 LEELHKAEDSLLAAEEAAAKAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAA 120
EEL + A ++ + EA +A L EEEL+ Q + ++ +A + A
Sbjct: 1714 AEELASSLSGRNALQDEKRRLEARIAQL-------EEELEEEQGNMEAMSDRVRKATQQA 1766
Query: 121 DESERGMKVIESRAQKDE---EKMEIQEIQLKEAKHIAEDADR-KYEE----VARKLVII 172
++ + S AQK+E +++E Q +L+ H E A + K++ + K+ +
Sbjct: 1767 EQLSNELATERSTAQKNESARQQLERQNKELRSKLHEMEGAVKSKFKSTIAALEAKIAQL 1826
Query: 173 ESDLERAEERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKEDRYEEEIKVLSDKL 232
E +E+ + + + +++LK + ++ AE+Y ++ ++ +K L +L
Sbjct: 1827 EEQVEQEAREKQAATKSLKQKDKKLKEILLQVEDERKMAEQYKEQAEKGNARVKQLKRQL 1886
Query: 233 KEAETRAEFAERSVTKLEKSIDDLEE 258
+EAE ++ + KL++ +D+ E
Sbjct: 1887 EEAEEESQRINANRRKLQRELDEATE 1912
Score = 71.6 bits (174), Expect = 7e-13
Identities = 61/276 (22%), Positives = 130/276 (47%), Gaps = 21/276 (7%)
Query: 15 KENALDRAEQAEADKKAAEDRSKQLEEDIAAKEKLLRVSEDERDRVLEELHKAEDSLLAA 74
K L + + E + +A ED ++ +E E L+ E + ++ EE + ++ L A
Sbjct: 840 KVKPLLQVTRQEEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAE 899
Query: 75 EEAAAKAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIESRA 134
E A+AE L + Q +EE L + RL + ++ + A+ + ++++
Sbjct: 900 TELYAEAEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQ--AERKKMAQQMLDLEE 957
Query: 135 QKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAEERAELSEGKCAELE 194
Q +EE+ Q++QL++ A+ K +++ ++++++ + + +L LE
Sbjct: 958 QLEEEEAARQKLQLEKVT-----AEAKIKKLEDEILVMDDQNNKLSKERKL-------LE 1005
Query: 195 EELKTVTNNLKSLEAQAEKYSQKEDRYEEEIKVLSDKLKEAETRAEFAERSVTKLE---- 250
E + +T NL E +A+ ++ ++++E I L +LK+ E + E+ KLE
Sbjct: 1006 ERISDLTTNLAEEEEKAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDAS 1065
Query: 251 ---KSIDDLEEKVAHAKEENLSMHQMLDQTLLELNN 283
+ I DL+ ++A K + + L L L++
Sbjct: 1066 DFHEQIADLQAQIAELKMQLAKKEEELQAALARLDD 1101
Score = 70.1 bits (170), Expect = 2e-12
Identities = 68/280 (24%), Positives = 132/280 (47%), Gaps = 24/280 (8%)
Query: 4 IKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEEDIAAK----EKLLRV----SED 55
++K + L+ E + E+ E + +A ED +LE ++ A E+ L+ +E+
Sbjct: 1530 LEKSKRALETQMEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQFERDLQARDEQNEE 1589
Query: 56 ERDRVLEELHKAEDSL-------LAAEEAAAKAEADVASLNRR----IQLVEE---ELDR 101
+R ++ +LH+ E L A A K E D+ L + I+ EE +L +
Sbjct: 1590 KRRQLQRQLHEYETELEDERKQRALAAAAKKKLEGDLKDLELQADSAIKGREEAIKQLRK 1649
Query: 102 AQERLATALQKLEEAEKAADESERGMKVIESRAQKDE-EKMEIQEIQLKEAKHIAEDADR 160
Q ++ ++LE+A + DE K E +A+ E + M++QE L A+ + AD
Sbjct: 1650 LQAQMKDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQE-DLAAAERARKQADL 1708
Query: 161 KYEEVARKLVIIESDLERAEERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKEDR 220
+ EE+A +L S ++ E + A+LEEEL+ N++++ + K +Q+ ++
Sbjct: 1709 EKEELAEELASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQ 1768
Query: 221 YEEEIKVLSDKLKEAETRAEFAERSVTKLEKSIDDLEEKV 260
E+ ++ E+ + ER +L + ++E V
Sbjct: 1769 LSNELATERSTAQKNESARQQLERQNKELRSKLHEMEGAV 1808
Score = 65.5 bits (158), Expect = 5e-11
Identities = 65/270 (24%), Positives = 128/270 (47%), Gaps = 25/270 (9%)
Query: 16 ENALDRAEQAEADKKAAE----DRSKQLEEDIAAKEKLLRVSEDERDRVLEELHKAEDSL 71
E DR +Q +A++K D +QLEE+ AA++KL + E+ ++ K ED +
Sbjct: 932 EEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKL----QLEKVTAEAKIKKLEDEI 987
Query: 72 LAAEEAAAKAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIE 131
L ++ K L++ +L+EE + LA +K + K ++ E + +E
Sbjct: 988 LVMDDQNNK-------LSKERKLLEERISDLTTNLAEEEEKAKNLTKLKNKHESMISELE 1040
Query: 132 SRAQKDEE-KMEIQEIQLKEAKHIAEDADRKYEEVA-RKLVIIESDLERAEERAELSEGK 189
R +K+E+ + E+++++ K + DA +E++A + I E ++ A++ EL +
Sbjct: 1041 VRLKKEEKSRQELEKLKRK----LEGDASDFHEQIADLQAQIAELKMQLAKKEEEL-QAA 1095
Query: 190 CAELEEELKTVTNNLKSLEAQAEKYSQKEDRYEEEIKVLSDKLKEAETRAEFAERSVTKL 249
A L++E+ N LK + S ++ + E + K+ E E T+L
Sbjct: 1096 LARLDDEIAQKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEALKTEL 1155
Query: 250 EKSIDDL---EEKVAHAKEENLSMHQMLDQ 276
E ++D +E A ++E + + LD+
Sbjct: 1156 EDTLDSTATQQELRAKREQEVTVLKKALDE 1185
Score = 65.1 bits (157), Expect = 7e-11
Identities = 71/292 (24%), Positives = 128/292 (43%), Gaps = 27/292 (9%)
Query: 13 LDKENA--------LDRAEQ-AEADKKAAEDRSKQLEEDIAAKEKLLRVSEDERDRVLEE 63
L+KENA L +A+Q E KK E + ++L+ + E+ D+ ++ E
Sbjct: 1229 LEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERARAELNDKVHKLQNE 1288
Query: 64 LHKAEDSLLAAEEAAAKAEADVASLNRRIQLVEEELD---RAQERLATALQKLEEAEKAA 120
+ L AE A K DVASL+ ++Q +E L R + ++T L++LEE +
Sbjct: 1289 VESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEERNSL 1348
Query: 121 -DESERGMKVIESRAQKDEEKMEIQEIQLKEAK----------HIAEDADRKYEEVARKL 169
D+ + M+ Q E + IQL ++K E+ +++++ L
Sbjct: 1349 QDQLDEEMEA----KQNLERHISTLNIQLSDSKKKLQDFASTVEALEEGKKRFQKEIENL 1404
Query: 170 VIIESDLERAEERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKEDRYEEEIKVLS 229
+ A ++ E ++ + + ++L +N + L + EK +K D+ E K +S
Sbjct: 1405 TQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEEKNIS 1464
Query: 230 DKLKEAETRAEFAERSVTKLEKSIDDLEEKVAHAKEENLSMHQMLDQTLLEL 281
K + RAE R S+ E+ AKEE ++ML + +L
Sbjct: 1465 SKYADERDRAEAEAREKETKALSLARALEEALEAKEELERTNKMLKAEMEDL 1516
Score = 64.7 bits (156), Expect = 9e-11
Identities = 70/301 (23%), Positives = 144/301 (47%), Gaps = 36/301 (11%)
Query: 4 IKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEEDIAAKEKLLRVSEDERDRVLEE 63
+K +M+ L K++ + E K+A E + ++++ + E L+ +ED + R+
Sbjct: 1509 LKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQATEDAKLRLEVN 1568
Query: 64 LH----KAEDSLLAAEEAAAKAEADVASLNRRIQLVEEELD--RAQERLATALQK----- 112
+ + E L A +E + E L R++ E EL+ R Q LA A +K
Sbjct: 1569 MQALKGQFERDLQARDE---QNEEKRRQLQRQLHEYETELEDERKQRALAAAAKKKLEGD 1625
Query: 113 LEEAEKAADESERGMKVIESRAQKDEEKMEIQEIQLKEAKH-------IAEDADRKYEEV 165
L++ E AD + +G + + +K + +M+ + +L++A+ A++ ++K + +
Sbjct: 1626 LKDLELQADSAIKGREEAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKENEKKAKSL 1685
Query: 166 ARKLVIIESDLERAEERAELSEGKCAELEEELKTVTNNLKSLEAQAEKY----SQKEDRY 221
L+ ++ DL AE + ++ + EL EEL + + +L+ + + +Q E+
Sbjct: 1686 EADLMQLQEDLAAAERARKQADLEKEELAEELASSLSGRNALQDEKRRLEARIAQLEEEL 1745
Query: 222 EEE---IKVLSDKLKEAETRAE------FAERSVTKLEKSIDDLEEKVAHAKEENLSMHQ 272
EEE ++ +SD++++A +AE ERS + +S E+ KE +H+
Sbjct: 1746 EEEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKNESARQQLER--QNKELRSKLHE 1803
Query: 273 M 273
M
Sbjct: 1804 M 1804
Score = 62.0 bits (149), Expect = 6e-10
Identities = 75/301 (24%), Positives = 133/301 (44%), Gaps = 43/301 (14%)
Query: 7 KMQMLKLDKE--NALDRAEQAEADKKAAEDRSKQLE-------EDIAAK-------EKLL 50
KMQ+ K ++E AL R + A K A + ++LE ED+ ++ EK
Sbjct: 1082 KMQLAKKEEELQAALARLDDEIAQKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQK 1141
Query: 51 RVSEDERDRVLEELHKAEDSLLAAEEAAAKAEADVASLNRRIQLVEEELDRAQERLATAL 110
R +E + + EL DS +E AK E +V L + + +EE + ++
Sbjct: 1142 RDLGEELEALKTELEDTLDSTATQQELRAKREQEVTVLKKAL---DEETRSHEAQVQEMR 1198
Query: 111 QKLEEAEKAADESERGMKVIESRAQKDEEKMEIQEIQLK-------EAKHIAEDADRKYE 163
QK +A + E K ++ K+++ +E + L +AK E +K E
Sbjct: 1199 QKHAQAVEELTEQLEQFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLE 1258
Query: 164 EVARKLVIIESDLERAEERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKEDRYEE 223
++L SD ERA RAEL++ K +L+ E+++VT L E +A K ++
Sbjct: 1259 AQVQELQSKCSDGERA--RAELND-KVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSS 1315
Query: 224 EIKVLSDKLKEAETRAEFAERSVTKLEKSIDDLEEKVAHAKEENLSMHQMLDQTLLELNN 283
+++ + L+E ETR + ++ K+ +EE S+ LD+ + N
Sbjct: 1316 QLQDTQELLQE-ETRQKL-------------NVSTKLRQLEEERNSLQDQLDEEMEAKQN 1361
Query: 284 M 284
+
Sbjct: 1362 L 1362
Score = 61.2 bits (147), Expect = 1e-09
Identities = 58/303 (19%), Positives = 139/303 (45%), Gaps = 35/303 (11%)
Query: 6 KKMQMLKLDKENALD-----------RAEQAEADKKAAEDRSKQLEEDIAAKEKLLRVSE 54
++++ LK + E+ LD R ++ KKA ++ ++ E + + +
Sbjct: 1146 EELEALKTELEDTLDSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAV 1205
Query: 55 DERDRVLEELHKAEDSLLAAEEAAAKAEADVASLNRRIQLVEEELDRAQERLATALQKLE 114
+E LE+ +A+ +L ++ K AD+A R + ++E++ +++L +Q+L
Sbjct: 1206 EELTEQLEQFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQEL- 1264
Query: 115 EAEKAADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIES 174
+ + ER +RA+ +++ ++Q +++ + +A+ K ++A+ + + S
Sbjct: 1265 --QSKCSDGER------ARAELNDKVHKLQN-EVESVTGMLNEAEGKAIKLAKDVASLSS 1315
Query: 175 DLERAEERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKEDRYEEEIKVLS----- 229
L+ +E + + + +L+ + SL+ Q ++ + + E I L+
Sbjct: 1316 QLQDTQELLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSD 1375
Query: 230 --DKLKEAETRAEFAERSVTKLEKSIDDL-----EEKVAHAKEENLS--MHQMLDQTLLE 280
KL++ + E E + +K I++L E+ A+ K E + Q LD +++
Sbjct: 1376 SKKKLQDFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVD 1435
Query: 281 LNN 283
L+N
Sbjct: 1436 LDN 1438
Score = 57.4 bits (137), Expect = 1e-08
Identities = 56/282 (19%), Positives = 124/282 (43%), Gaps = 11/282 (3%)
Query: 1 MDAIKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEEDIAAKEKLLRVSEDERDRV 60
++ K ++Q D LD Q ++ E + ++ ++ +A ++ + DERDR
Sbjct: 1418 LEKTKNRLQQELDDLVVDLDNQRQLVSN---LEKKQRKFDQLLAEEKNISSKYADERDRA 1474
Query: 61 LEELHKAED---SLLAAEEAAAKAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAE 117
E + E SL A E A +A+ ++ N+ ++ E+L +++ + + +LE+++
Sbjct: 1475 EAEAREKETKALSLARALEEALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSK 1534
Query: 118 KAADESERGMKV----IESRAQKDEEKMEIQEIQLKEAK-HIAEDADRKYEEVARKLVII 172
+A + MK +E Q E+ E+ ++ K D + E+ K +
Sbjct: 1535 RALETQMEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQFERDLQARDEQNEEKRRQL 1594
Query: 173 ESDLERAEERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKEDRYEEEIKVLSDKL 232
+ L E E + A K + +LK LE QA+ + + ++++ L ++
Sbjct: 1595 QRQLHEYETELEDERKQRALAAAAKKKLEGDLKDLELQADSAIKGREEAIKQLRKLQAQM 1654
Query: 233 KEAETRAEFAERSVTKLEKSIDDLEEKVAHAKEENLSMHQML 274
K+ + E A S ++ + + E+K + + + + + L
Sbjct: 1655 KDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQEDL 1696
Score = 49.7 bits (117), Expect = 3e-06
Identities = 54/274 (19%), Positives = 120/274 (43%), Gaps = 12/274 (4%)
Query: 15 KENALDRAEQAEADKKAAEDRSKQLEEDIAAKEKLLRVSEDERDRVLEELHKAED---SL 71
K N + Q E ++ + +D QL+E++ AK+ L R ++ + K +D ++
Sbjct: 1331 KLNVSTKLRQLEEERNSLQD---QLDEEMEAKQNLERHISTLNIQLSDSKKKLQDFASTV 1387
Query: 72 LAAEEAAAKAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIE 131
A EE + + ++ +L ++ + D+ ++ Q+L++ D + + +E
Sbjct: 1388 EALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLE 1447
Query: 132 SRAQK-DEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAEERAELSEGKC 190
+ +K D+ E + I K A + A+ + E K + + LE A E E E
Sbjct: 1448 KKQRKFDQLLAEEKNISSKYADE-RDRAEAEAREKETKALSLARALEEALEAKEELERTN 1506
Query: 191 AELEEELKTVTNNLKSLEAQAEKYSQKEDRYEEEIKVLSDKLKEAETRAEFAERSVTKLE 250
L+ E++ + ++ + + + + E +++ + +L+E E + E + +LE
Sbjct: 1507 KMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQATEDAKLRLE 1566
Query: 251 KSIDDL----EEKVAHAKEENLSMHQMLDQTLLE 280
++ L E + E+N + L + L E
Sbjct: 1567 VNMQALKGQFERDLQARDEQNEEKRRQLQRQLHE 1600
Score = 44.7 bits (104), Expect = 9e-05
Identities = 40/145 (27%), Positives = 70/145 (48%), Gaps = 15/145 (10%)
Query: 20 DRAEQAEADKKAAEDRSKQLEEDIAAKEKLLRVSEDERDRVLEELHKAEDSLLAAEEAAA 79
++ EQ +K+AA KQ ++ + KE LL+V EDER + E +K E A
Sbjct: 1828 EQVEQEAREKQAATKSLKQKDKKL--KEILLQV-EDERK--MAEQYK---------EQAE 1873
Query: 80 KAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIESRAQKDEE 139
K A V L R+++ EEE R ++L+EA ++ + R + ++S+ ++ E
Sbjct: 1874 KGNARVKQLKRQLEEAEEESQRINANRRKLQRELDEATESNEAMGREVNALKSKLRRGNE 1933
Query: 140 KMEIQEIQLKEAKHIAEDADRKYEE 164
+ + + + E+AD EE
Sbjct: 1934 TSFVPS-RRSGGRRVIENADGSEEE 1957
>gi|92091586 smooth muscle myosin heavy chain 11 isoform SM1B [Homo
sapiens]
Length = 1979
Score = 82.8 bits (203), Expect = 3e-16
Identities = 58/266 (21%), Positives = 130/266 (48%), Gaps = 15/266 (5%)
Query: 1 MDAIKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEEDIAAKEKLLRVSEDERDRV 60
M +++++ + ++ A++ E K+ E QL+ED+AA E+ + ++ E++ +
Sbjct: 1661 MKDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAERARKQADLEKEEL 1720
Query: 61 LEELHKAEDSLLAAEEAAAKAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAA 120
EEL + A ++ + EA +A L EEEL+ Q + ++ +A + A
Sbjct: 1721 AEELASSLSGRNALQDEKRRLEARIAQL-------EEELEEEQGNMEAMSDRVRKATQQA 1773
Query: 121 DESERGMKVIESRAQKDE---EKMEIQEIQLKEAKHIAEDADR-KYEE----VARKLVII 172
++ + S AQK+E +++E Q +L+ H E A + K++ + K+ +
Sbjct: 1774 EQLSNELATERSTAQKNESARQQLERQNKELRSKLHEMEGAVKSKFKSTIAALEAKIAQL 1833
Query: 173 ESDLERAEERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKEDRYEEEIKVLSDKL 232
E +E+ + + + +++LK + ++ AE+Y ++ ++ +K L +L
Sbjct: 1834 EEQVEQEAREKQAATKSLKQKDKKLKEILLQVEDERKMAEQYKEQAEKGNARVKQLKRQL 1893
Query: 233 KEAETRAEFAERSVTKLEKSIDDLEE 258
+EAE ++ + KL++ +D+ E
Sbjct: 1894 EEAEEESQRINANRRKLQRELDEATE 1919
Score = 71.6 bits (174), Expect = 7e-13
Identities = 61/276 (22%), Positives = 130/276 (47%), Gaps = 21/276 (7%)
Query: 15 KENALDRAEQAEADKKAAEDRSKQLEEDIAAKEKLLRVSEDERDRVLEELHKAEDSLLAA 74
K L + + E + +A ED ++ +E E L+ E + ++ EE + ++ L A
Sbjct: 847 KVKPLLQVTRQEEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAE 906
Query: 75 EEAAAKAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIESRA 134
E A+AE L + Q +EE L + RL + ++ + A+ + ++++
Sbjct: 907 TELYAEAEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQ--AERKKMAQQMLDLEE 964
Query: 135 QKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAEERAELSEGKCAELE 194
Q +EE+ Q++QL++ A+ K +++ ++++++ + + +L LE
Sbjct: 965 QLEEEEAARQKLQLEKVT-----AEAKIKKLEDEILVMDDQNNKLSKERKL-------LE 1012
Query: 195 EELKTVTNNLKSLEAQAEKYSQKEDRYEEEIKVLSDKLKEAETRAEFAERSVTKLE---- 250
E + +T NL E +A+ ++ ++++E I L +LK+ E + E+ KLE
Sbjct: 1013 ERISDLTTNLAEEEEKAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDAS 1072
Query: 251 ---KSIDDLEEKVAHAKEENLSMHQMLDQTLLELNN 283
+ I DL+ ++A K + + L L L++
Sbjct: 1073 DFHEQIADLQAQIAELKMQLAKKEEELQAALARLDD 1108
Score = 70.1 bits (170), Expect = 2e-12
Identities = 68/280 (24%), Positives = 132/280 (47%), Gaps = 24/280 (8%)
Query: 4 IKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEEDIAAK----EKLLRV----SED 55
++K + L+ E + E+ E + +A ED +LE ++ A E+ L+ +E+
Sbjct: 1537 LEKSKRALETQMEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQFERDLQARDEQNEE 1596
Query: 56 ERDRVLEELHKAEDSL-------LAAEEAAAKAEADVASLNRR----IQLVEE---ELDR 101
+R ++ +LH+ E L A A K E D+ L + I+ EE +L +
Sbjct: 1597 KRRQLQRQLHEYETELEDERKQRALAAAAKKKLEGDLKDLELQADSAIKGREEAIKQLRK 1656
Query: 102 AQERLATALQKLEEAEKAADESERGMKVIESRAQKDE-EKMEIQEIQLKEAKHIAEDADR 160
Q ++ ++LE+A + DE K E +A+ E + M++QE L A+ + AD
Sbjct: 1657 LQAQMKDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQE-DLAAAERARKQADL 1715
Query: 161 KYEEVARKLVIIESDLERAEERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKEDR 220
+ EE+A +L S ++ E + A+LEEEL+ N++++ + K +Q+ ++
Sbjct: 1716 EKEELAEELASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQ 1775
Query: 221 YEEEIKVLSDKLKEAETRAEFAERSVTKLEKSIDDLEEKV 260
E+ ++ E+ + ER +L + ++E V
Sbjct: 1776 LSNELATERSTAQKNESARQQLERQNKELRSKLHEMEGAV 1815
Score = 65.5 bits (158), Expect = 5e-11
Identities = 65/270 (24%), Positives = 128/270 (47%), Gaps = 25/270 (9%)
Query: 16 ENALDRAEQAEADKKAAE----DRSKQLEEDIAAKEKLLRVSEDERDRVLEELHKAEDSL 71
E DR +Q +A++K D +QLEE+ AA++KL + E+ ++ K ED +
Sbjct: 939 EEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKL----QLEKVTAEAKIKKLEDEI 994
Query: 72 LAAEEAAAKAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIE 131
L ++ K L++ +L+EE + LA +K + K ++ E + +E
Sbjct: 995 LVMDDQNNK-------LSKERKLLEERISDLTTNLAEEEEKAKNLTKLKNKHESMISELE 1047
Query: 132 SRAQKDEE-KMEIQEIQLKEAKHIAEDADRKYEEVA-RKLVIIESDLERAEERAELSEGK 189
R +K+E+ + E+++++ K + DA +E++A + I E ++ A++ EL +
Sbjct: 1048 VRLKKEEKSRQELEKLKRK----LEGDASDFHEQIADLQAQIAELKMQLAKKEEEL-QAA 1102
Query: 190 CAELEEELKTVTNNLKSLEAQAEKYSQKEDRYEEEIKVLSDKLKEAETRAEFAERSVTKL 249
A L++E+ N LK + S ++ + E + K+ E E T+L
Sbjct: 1103 LARLDDEIAQKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEALKTEL 1162
Query: 250 EKSIDDL---EEKVAHAKEENLSMHQMLDQ 276
E ++D +E A ++E + + LD+
Sbjct: 1163 EDTLDSTATQQELRAKREQEVTVLKKALDE 1192
Score = 65.1 bits (157), Expect = 7e-11
Identities = 71/292 (24%), Positives = 128/292 (43%), Gaps = 27/292 (9%)
Query: 13 LDKENA--------LDRAEQ-AEADKKAAEDRSKQLEEDIAAKEKLLRVSEDERDRVLEE 63
L+KENA L +A+Q E KK E + ++L+ + E+ D+ ++ E
Sbjct: 1236 LEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERARAELNDKVHKLQNE 1295
Query: 64 LHKAEDSLLAAEEAAAKAEADVASLNRRIQLVEEELD---RAQERLATALQKLEEAEKAA 120
+ L AE A K DVASL+ ++Q +E L R + ++T L++LEE +
Sbjct: 1296 VESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEERNSL 1355
Query: 121 -DESERGMKVIESRAQKDEEKMEIQEIQLKEAK----------HIAEDADRKYEEVARKL 169
D+ + M+ Q E + IQL ++K E+ +++++ L
Sbjct: 1356 QDQLDEEMEA----KQNLERHISTLNIQLSDSKKKLQDFASTVEALEEGKKRFQKEIENL 1411
Query: 170 VIIESDLERAEERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKEDRYEEEIKVLS 229
+ A ++ E ++ + + ++L +N + L + EK +K D+ E K +S
Sbjct: 1412 TQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEEKNIS 1471
Query: 230 DKLKEAETRAEFAERSVTKLEKSIDDLEEKVAHAKEENLSMHQMLDQTLLEL 281
K + RAE R S+ E+ AKEE ++ML + +L
Sbjct: 1472 SKYADERDRAEAEAREKETKALSLARALEEALEAKEELERTNKMLKAEMEDL 1523
Score = 64.7 bits (156), Expect = 9e-11
Identities = 70/301 (23%), Positives = 144/301 (47%), Gaps = 36/301 (11%)
Query: 4 IKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEEDIAAKEKLLRVSEDERDRVLEE 63
+K +M+ L K++ + E K+A E + ++++ + E L+ +ED + R+
Sbjct: 1516 LKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQATEDAKLRLEVN 1575
Query: 64 LH----KAEDSLLAAEEAAAKAEADVASLNRRIQLVEEELD--RAQERLATALQK----- 112
+ + E L A +E + E L R++ E EL+ R Q LA A +K
Sbjct: 1576 MQALKGQFERDLQARDE---QNEEKRRQLQRQLHEYETELEDERKQRALAAAAKKKLEGD 1632
Query: 113 LEEAEKAADESERGMKVIESRAQKDEEKMEIQEIQLKEAKH-------IAEDADRKYEEV 165
L++ E AD + +G + + +K + +M+ + +L++A+ A++ ++K + +
Sbjct: 1633 LKDLELQADSAIKGREEAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKENEKKAKSL 1692
Query: 166 ARKLVIIESDLERAEERAELSEGKCAELEEELKTVTNNLKSLEAQAEKY----SQKEDRY 221
L+ ++ DL AE + ++ + EL EEL + + +L+ + + +Q E+
Sbjct: 1693 EADLMQLQEDLAAAERARKQADLEKEELAEELASSLSGRNALQDEKRRLEARIAQLEEEL 1752
Query: 222 EEE---IKVLSDKLKEAETRAE------FAERSVTKLEKSIDDLEEKVAHAKEENLSMHQ 272
EEE ++ +SD++++A +AE ERS + +S E+ KE +H+
Sbjct: 1753 EEEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKNESARQQLER--QNKELRSKLHE 1810
Query: 273 M 273
M
Sbjct: 1811 M 1811
Score = 62.0 bits (149), Expect = 6e-10
Identities = 75/301 (24%), Positives = 133/301 (44%), Gaps = 43/301 (14%)
Query: 7 KMQMLKLDKE--NALDRAEQAEADKKAAEDRSKQLE-------EDIAAK-------EKLL 50
KMQ+ K ++E AL R + A K A + ++LE ED+ ++ EK
Sbjct: 1089 KMQLAKKEEELQAALARLDDEIAQKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQK 1148
Query: 51 RVSEDERDRVLEELHKAEDSLLAAEEAAAKAEADVASLNRRIQLVEEELDRAQERLATAL 110
R +E + + EL DS +E AK E +V L + + +EE + ++
Sbjct: 1149 RDLGEELEALKTELEDTLDSTATQQELRAKREQEVTVLKKAL---DEETRSHEAQVQEMR 1205
Query: 111 QKLEEAEKAADESERGMKVIESRAQKDEEKMEIQEIQLK-------EAKHIAEDADRKYE 163
QK +A + E K ++ K+++ +E + L +AK E +K E
Sbjct: 1206 QKHAQAVEELTEQLEQFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLE 1265
Query: 164 EVARKLVIIESDLERAEERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKEDRYEE 223
++L SD ERA RAEL++ K +L+ E+++VT L E +A K ++
Sbjct: 1266 AQVQELQSKCSDGERA--RAELND-KVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSS 1322
Query: 224 EIKVLSDKLKEAETRAEFAERSVTKLEKSIDDLEEKVAHAKEENLSMHQMLDQTLLELNN 283
+++ + L+E ETR + ++ K+ +EE S+ LD+ + N
Sbjct: 1323 QLQDTQELLQE-ETRQKL-------------NVSTKLRQLEEERNSLQDQLDEEMEAKQN 1368
Query: 284 M 284
+
Sbjct: 1369 L 1369
Score = 61.2 bits (147), Expect = 1e-09
Identities = 58/303 (19%), Positives = 139/303 (45%), Gaps = 35/303 (11%)
Query: 6 KKMQMLKLDKENALD-----------RAEQAEADKKAAEDRSKQLEEDIAAKEKLLRVSE 54
++++ LK + E+ LD R ++ KKA ++ ++ E + + +
Sbjct: 1153 EELEALKTELEDTLDSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAV 1212
Query: 55 DERDRVLEELHKAEDSLLAAEEAAAKAEADVASLNRRIQLVEEELDRAQERLATALQKLE 114
+E LE+ +A+ +L ++ K AD+A R + ++E++ +++L +Q+L
Sbjct: 1213 EELTEQLEQFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQEL- 1271
Query: 115 EAEKAADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIES 174
+ + ER +RA+ +++ ++Q +++ + +A+ K ++A+ + + S
Sbjct: 1272 --QSKCSDGER------ARAELNDKVHKLQN-EVESVTGMLNEAEGKAIKLAKDVASLSS 1322
Query: 175 DLERAEERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKEDRYEEEIKVLS----- 229
L+ +E + + + +L+ + SL+ Q ++ + + E I L+
Sbjct: 1323 QLQDTQELLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSD 1382
Query: 230 --DKLKEAETRAEFAERSVTKLEKSIDDL-----EEKVAHAKEENLS--MHQMLDQTLLE 280
KL++ + E E + +K I++L E+ A+ K E + Q LD +++
Sbjct: 1383 SKKKLQDFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVD 1442
Query: 281 LNN 283
L+N
Sbjct: 1443 LDN 1445
Score = 57.4 bits (137), Expect = 1e-08
Identities = 56/282 (19%), Positives = 124/282 (43%), Gaps = 11/282 (3%)
Query: 1 MDAIKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEEDIAAKEKLLRVSEDERDRV 60
++ K ++Q D LD Q ++ E + ++ ++ +A ++ + DERDR
Sbjct: 1425 LEKTKNRLQQELDDLVVDLDNQRQLVSN---LEKKQRKFDQLLAEEKNISSKYADERDRA 1481
Query: 61 LEELHKAED---SLLAAEEAAAKAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAE 117
E + E SL A E A +A+ ++ N+ ++ E+L +++ + + +LE+++
Sbjct: 1482 EAEAREKETKALSLARALEEALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSK 1541
Query: 118 KAADESERGMKV----IESRAQKDEEKMEIQEIQLKEAK-HIAEDADRKYEEVARKLVII 172
+A + MK +E Q E+ E+ ++ K D + E+ K +
Sbjct: 1542 RALETQMEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQFERDLQARDEQNEEKRRQL 1601
Query: 173 ESDLERAEERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKEDRYEEEIKVLSDKL 232
+ L E E + A K + +LK LE QA+ + + ++++ L ++
Sbjct: 1602 QRQLHEYETELEDERKQRALAAAAKKKLEGDLKDLELQADSAIKGREEAIKQLRKLQAQM 1661
Query: 233 KEAETRAEFAERSVTKLEKSIDDLEEKVAHAKEENLSMHQML 274
K+ + E A S ++ + + E+K + + + + + L
Sbjct: 1662 KDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQEDL 1703
Score = 49.7 bits (117), Expect = 3e-06
Identities = 54/274 (19%), Positives = 120/274 (43%), Gaps = 12/274 (4%)
Query: 15 KENALDRAEQAEADKKAAEDRSKQLEEDIAAKEKLLRVSEDERDRVLEELHKAED---SL 71
K N + Q E ++ + +D QL+E++ AK+ L R ++ + K +D ++
Sbjct: 1338 KLNVSTKLRQLEEERNSLQD---QLDEEMEAKQNLERHISTLNIQLSDSKKKLQDFASTV 1394
Query: 72 LAAEEAAAKAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIE 131
A EE + + ++ +L ++ + D+ ++ Q+L++ D + + +E
Sbjct: 1395 EALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLE 1454
Query: 132 SRAQK-DEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAEERAELSEGKC 190
+ +K D+ E + I K A + A+ + E K + + LE A E E E
Sbjct: 1455 KKQRKFDQLLAEEKNISSKYADE-RDRAEAEAREKETKALSLARALEEALEAKEELERTN 1513
Query: 191 AELEEELKTVTNNLKSLEAQAEKYSQKEDRYEEEIKVLSDKLKEAETRAEFAERSVTKLE 250
L+ E++ + ++ + + + + E +++ + +L+E E + E + +LE
Sbjct: 1514 KMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQATEDAKLRLE 1573
Query: 251 KSIDDL----EEKVAHAKEENLSMHQMLDQTLLE 280
++ L E + E+N + L + L E
Sbjct: 1574 VNMQALKGQFERDLQARDEQNEEKRRQLQRQLHE 1607
Score = 44.7 bits (104), Expect = 9e-05
Identities = 40/145 (27%), Positives = 70/145 (48%), Gaps = 15/145 (10%)
Query: 20 DRAEQAEADKKAAEDRSKQLEEDIAAKEKLLRVSEDERDRVLEELHKAEDSLLAAEEAAA 79
++ EQ +K+AA KQ ++ + KE LL+V EDER + E +K E A
Sbjct: 1835 EQVEQEAREKQAATKSLKQKDKKL--KEILLQV-EDERK--MAEQYK---------EQAE 1880
Query: 80 KAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIESRAQKDEE 139
K A V L R+++ EEE R ++L+EA ++ + R + ++S+ ++ E
Sbjct: 1881 KGNARVKQLKRQLEEAEEESQRINANRRKLQRELDEATESNEAMGREVNALKSKLRRGNE 1940
Query: 140 KMEIQEIQLKEAKHIAEDADRKYEE 164
+ + + + E+AD EE
Sbjct: 1941 TSFVPS-RRSGGRRVIENADGSEEE 1964
>gi|92091583 smooth muscle myosin heavy chain 11 isoform SM2B [Homo
sapiens]
Length = 1945
Score = 82.8 bits (203), Expect = 3e-16
Identities = 58/266 (21%), Positives = 130/266 (48%), Gaps = 15/266 (5%)
Query: 1 MDAIKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEEDIAAKEKLLRVSEDERDRV 60
M +++++ + ++ A++ E K+ E QL+ED+AA E+ + ++ E++ +
Sbjct: 1661 MKDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAERARKQADLEKEEL 1720
Query: 61 LEELHKAEDSLLAAEEAAAKAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAA 120
EEL + A ++ + EA +A L EEEL+ Q + ++ +A + A
Sbjct: 1721 AEELASSLSGRNALQDEKRRLEARIAQL-------EEELEEEQGNMEAMSDRVRKATQQA 1773
Query: 121 DESERGMKVIESRAQKDE---EKMEIQEIQLKEAKHIAEDADR-KYEE----VARKLVII 172
++ + S AQK+E +++E Q +L+ H E A + K++ + K+ +
Sbjct: 1774 EQLSNELATERSTAQKNESARQQLERQNKELRSKLHEMEGAVKSKFKSTIAALEAKIAQL 1833
Query: 173 ESDLERAEERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKEDRYEEEIKVLSDKL 232
E +E+ + + + +++LK + ++ AE+Y ++ ++ +K L +L
Sbjct: 1834 EEQVEQEAREKQAATKSLKQKDKKLKEILLQVEDERKMAEQYKEQAEKGNARVKQLKRQL 1893
Query: 233 KEAETRAEFAERSVTKLEKSIDDLEE 258
+EAE ++ + KL++ +D+ E
Sbjct: 1894 EEAEEESQRINANRRKLQRELDEATE 1919
Score = 71.6 bits (174), Expect = 7e-13
Identities = 61/276 (22%), Positives = 130/276 (47%), Gaps = 21/276 (7%)
Query: 15 KENALDRAEQAEADKKAAEDRSKQLEEDIAAKEKLLRVSEDERDRVLEELHKAEDSLLAA 74
K L + + E + +A ED ++ +E E L+ E + ++ EE + ++ L A
Sbjct: 847 KVKPLLQVTRQEEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAE 906
Query: 75 EEAAAKAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIESRA 134
E A+AE L + Q +EE L + RL + ++ + A+ + ++++
Sbjct: 907 TELYAEAEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQ--AERKKMAQQMLDLEE 964
Query: 135 QKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAEERAELSEGKCAELE 194
Q +EE+ Q++QL++ A+ K +++ ++++++ + + +L LE
Sbjct: 965 QLEEEEAARQKLQLEKVT-----AEAKIKKLEDEILVMDDQNNKLSKERKL-------LE 1012
Query: 195 EELKTVTNNLKSLEAQAEKYSQKEDRYEEEIKVLSDKLKEAETRAEFAERSVTKLE---- 250
E + +T NL E +A+ ++ ++++E I L +LK+ E + E+ KLE
Sbjct: 1013 ERISDLTTNLAEEEEKAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDAS 1072
Query: 251 ---KSIDDLEEKVAHAKEENLSMHQMLDQTLLELNN 283
+ I DL+ ++A K + + L L L++
Sbjct: 1073 DFHEQIADLQAQIAELKMQLAKKEEELQAALARLDD 1108
Score = 70.1 bits (170), Expect = 2e-12
Identities = 68/280 (24%), Positives = 132/280 (47%), Gaps = 24/280 (8%)
Query: 4 IKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEEDIAAK----EKLLRV----SED 55
++K + L+ E + E+ E + +A ED +LE ++ A E+ L+ +E+
Sbjct: 1537 LEKSKRALETQMEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQFERDLQARDEQNEE 1596
Query: 56 ERDRVLEELHKAEDSL-------LAAEEAAAKAEADVASLNRR----IQLVEE---ELDR 101
+R ++ +LH+ E L A A K E D+ L + I+ EE +L +
Sbjct: 1597 KRRQLQRQLHEYETELEDERKQRALAAAAKKKLEGDLKDLELQADSAIKGREEAIKQLRK 1656
Query: 102 AQERLATALQKLEEAEKAADESERGMKVIESRAQKDE-EKMEIQEIQLKEAKHIAEDADR 160
Q ++ ++LE+A + DE K E +A+ E + M++QE L A+ + AD
Sbjct: 1657 LQAQMKDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQE-DLAAAERARKQADL 1715
Query: 161 KYEEVARKLVIIESDLERAEERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKEDR 220
+ EE+A +L S ++ E + A+LEEEL+ N++++ + K +Q+ ++
Sbjct: 1716 EKEELAEELASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQ 1775
Query: 221 YEEEIKVLSDKLKEAETRAEFAERSVTKLEKSIDDLEEKV 260
E+ ++ E+ + ER +L + ++E V
Sbjct: 1776 LSNELATERSTAQKNESARQQLERQNKELRSKLHEMEGAV 1815
Score = 65.5 bits (158), Expect = 5e-11
Identities = 65/270 (24%), Positives = 128/270 (47%), Gaps = 25/270 (9%)
Query: 16 ENALDRAEQAEADKKAAE----DRSKQLEEDIAAKEKLLRVSEDERDRVLEELHKAEDSL 71
E DR +Q +A++K D +QLEE+ AA++KL + E+ ++ K ED +
Sbjct: 939 EEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKL----QLEKVTAEAKIKKLEDEI 994
Query: 72 LAAEEAAAKAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIE 131
L ++ K L++ +L+EE + LA +K + K ++ E + +E
Sbjct: 995 LVMDDQNNK-------LSKERKLLEERISDLTTNLAEEEEKAKNLTKLKNKHESMISELE 1047
Query: 132 SRAQKDEE-KMEIQEIQLKEAKHIAEDADRKYEEVA-RKLVIIESDLERAEERAELSEGK 189
R +K+E+ + E+++++ K + DA +E++A + I E ++ A++ EL +
Sbjct: 1048 VRLKKEEKSRQELEKLKRK----LEGDASDFHEQIADLQAQIAELKMQLAKKEEEL-QAA 1102
Query: 190 CAELEEELKTVTNNLKSLEAQAEKYSQKEDRYEEEIKVLSDKLKEAETRAEFAERSVTKL 249
A L++E+ N LK + S ++ + E + K+ E E T+L
Sbjct: 1103 LARLDDEIAQKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEALKTEL 1162
Query: 250 EKSIDDL---EEKVAHAKEENLSMHQMLDQ 276
E ++D +E A ++E + + LD+
Sbjct: 1163 EDTLDSTATQQELRAKREQEVTVLKKALDE 1192
Score = 65.1 bits (157), Expect = 7e-11
Identities = 71/292 (24%), Positives = 128/292 (43%), Gaps = 27/292 (9%)
Query: 13 LDKENA--------LDRAEQ-AEADKKAAEDRSKQLEEDIAAKEKLLRVSEDERDRVLEE 63
L+KENA L +A+Q E KK E + ++L+ + E+ D+ ++ E
Sbjct: 1236 LEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERARAELNDKVHKLQNE 1295
Query: 64 LHKAEDSLLAAEEAAAKAEADVASLNRRIQLVEEELD---RAQERLATALQKLEEAEKAA 120
+ L AE A K DVASL+ ++Q +E L R + ++T L++LEE +
Sbjct: 1296 VESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEERNSL 1355
Query: 121 -DESERGMKVIESRAQKDEEKMEIQEIQLKEAK----------HIAEDADRKYEEVARKL 169
D+ + M+ Q E + IQL ++K E+ +++++ L
Sbjct: 1356 QDQLDEEMEA----KQNLERHISTLNIQLSDSKKKLQDFASTVEALEEGKKRFQKEIENL 1411
Query: 170 VIIESDLERAEERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKEDRYEEEIKVLS 229
+ A ++ E ++ + + ++L +N + L + EK +K D+ E K +S
Sbjct: 1412 TQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEEKNIS 1471
Query: 230 DKLKEAETRAEFAERSVTKLEKSIDDLEEKVAHAKEENLSMHQMLDQTLLEL 281
K + RAE R S+ E+ AKEE ++ML + +L
Sbjct: 1472 SKYADERDRAEAEAREKETKALSLARALEEALEAKEELERTNKMLKAEMEDL 1523
Score = 64.7 bits (156), Expect = 9e-11
Identities = 70/301 (23%), Positives = 144/301 (47%), Gaps = 36/301 (11%)
Query: 4 IKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEEDIAAKEKLLRVSEDERDRVLEE 63
+K +M+ L K++ + E K+A E + ++++ + E L+ +ED + R+
Sbjct: 1516 LKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQATEDAKLRLEVN 1575
Query: 64 LH----KAEDSLLAAEEAAAKAEADVASLNRRIQLVEEELD--RAQERLATALQK----- 112
+ + E L A +E + E L R++ E EL+ R Q LA A +K
Sbjct: 1576 MQALKGQFERDLQARDE---QNEEKRRQLQRQLHEYETELEDERKQRALAAAAKKKLEGD 1632
Query: 113 LEEAEKAADESERGMKVIESRAQKDEEKMEIQEIQLKEAKH-------IAEDADRKYEEV 165
L++ E AD + +G + + +K + +M+ + +L++A+ A++ ++K + +
Sbjct: 1633 LKDLELQADSAIKGREEAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKENEKKAKSL 1692
Query: 166 ARKLVIIESDLERAEERAELSEGKCAELEEELKTVTNNLKSLEAQAEKY----SQKEDRY 221
L+ ++ DL AE + ++ + EL EEL + + +L+ + + +Q E+
Sbjct: 1693 EADLMQLQEDLAAAERARKQADLEKEELAEELASSLSGRNALQDEKRRLEARIAQLEEEL 1752
Query: 222 EEE---IKVLSDKLKEAETRAE------FAERSVTKLEKSIDDLEEKVAHAKEENLSMHQ 272
EEE ++ +SD++++A +AE ERS + +S E+ KE +H+
Sbjct: 1753 EEEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKNESARQQLER--QNKELRSKLHE 1810
Query: 273 M 273
M
Sbjct: 1811 M 1811
Score = 62.0 bits (149), Expect = 6e-10
Identities = 75/301 (24%), Positives = 133/301 (44%), Gaps = 43/301 (14%)
Query: 7 KMQMLKLDKE--NALDRAEQAEADKKAAEDRSKQLE-------EDIAAK-------EKLL 50
KMQ+ K ++E AL R + A K A + ++LE ED+ ++ EK
Sbjct: 1089 KMQLAKKEEELQAALARLDDEIAQKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQK 1148
Query: 51 RVSEDERDRVLEELHKAEDSLLAAEEAAAKAEADVASLNRRIQLVEEELDRAQERLATAL 110
R +E + + EL DS +E AK E +V L + + +EE + ++
Sbjct: 1149 RDLGEELEALKTELEDTLDSTATQQELRAKREQEVTVLKKAL---DEETRSHEAQVQEMR 1205
Query: 111 QKLEEAEKAADESERGMKVIESRAQKDEEKMEIQEIQLK-------EAKHIAEDADRKYE 163
QK +A + E K ++ K+++ +E + L +AK E +K E
Sbjct: 1206 QKHAQAVEELTEQLEQFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLE 1265
Query: 164 EVARKLVIIESDLERAEERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKEDRYEE 223
++L SD ERA RAEL++ K +L+ E+++VT L E +A K ++
Sbjct: 1266 AQVQELQSKCSDGERA--RAELND-KVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSS 1322
Query: 224 EIKVLSDKLKEAETRAEFAERSVTKLEKSIDDLEEKVAHAKEENLSMHQMLDQTLLELNN 283
+++ + L+E ETR + ++ K+ +EE S+ LD+ + N
Sbjct: 1323 QLQDTQELLQE-ETRQKL-------------NVSTKLRQLEEERNSLQDQLDEEMEAKQN 1368
Query: 284 M 284
+
Sbjct: 1369 L 1369
Score = 61.2 bits (147), Expect = 1e-09
Identities = 58/303 (19%), Positives = 139/303 (45%), Gaps = 35/303 (11%)
Query: 6 KKMQMLKLDKENALD-----------RAEQAEADKKAAEDRSKQLEEDIAAKEKLLRVSE 54
++++ LK + E+ LD R ++ KKA ++ ++ E + + +
Sbjct: 1153 EELEALKTELEDTLDSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAV 1212
Query: 55 DERDRVLEELHKAEDSLLAAEEAAAKAEADVASLNRRIQLVEEELDRAQERLATALQKLE 114
+E LE+ +A+ +L ++ K AD+A R + ++E++ +++L +Q+L
Sbjct: 1213 EELTEQLEQFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQEL- 1271
Query: 115 EAEKAADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIES 174
+ + ER +RA+ +++ ++Q +++ + +A+ K ++A+ + + S
Sbjct: 1272 --QSKCSDGER------ARAELNDKVHKLQN-EVESVTGMLNEAEGKAIKLAKDVASLSS 1322
Query: 175 DLERAEERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKEDRYEEEIKVLS----- 229
L+ +E + + + +L+ + SL+ Q ++ + + E I L+
Sbjct: 1323 QLQDTQELLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSD 1382
Query: 230 --DKLKEAETRAEFAERSVTKLEKSIDDL-----EEKVAHAKEENLS--MHQMLDQTLLE 280
KL++ + E E + +K I++L E+ A+ K E + Q LD +++
Sbjct: 1383 SKKKLQDFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVD 1442
Query: 281 LNN 283
L+N
Sbjct: 1443 LDN 1445
Score = 57.4 bits (137), Expect = 1e-08
Identities = 60/289 (20%), Positives = 135/289 (46%), Gaps = 25/289 (8%)
Query: 1 MDAIKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEEDIAAKEKLLRVSEDERDRV 60
++ K ++Q D LD Q ++ E + ++ ++ +A ++ + DERDR
Sbjct: 1425 LEKTKNRLQQELDDLVVDLDNQRQLVSN---LEKKQRKFDQLLAEEKNISSKYADERDRA 1481
Query: 61 LEELHKAED---SLLAAEEAAAKAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAE 117
E + E SL A E A +A+ ++ N+ ++ E+L +++ + + +LE+++
Sbjct: 1482 EAEAREKETKALSLARALEEALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSK 1541
Query: 118 KAADESERGMKV----IESRAQKDEE---KMEIQEIQLK-----EAKHIAEDADRKYEEV 165
+A + MK +E Q E+ ++E+ LK + + E + K ++
Sbjct: 1542 RALETQMEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQFERDLQARDEQNEEKRRQL 1601
Query: 166 ARKLVIIESDLERAEERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKEDRYEEEI 225
R+L E++LE +ER + + A+ K + +LK LE QA+ + + +++
Sbjct: 1602 QRQLHEYETELE--DERKQRALAAAAK-----KKLEGDLKDLELQADSAIKGREEAIKQL 1654
Query: 226 KVLSDKLKEAETRAEFAERSVTKLEKSIDDLEEKVAHAKEENLSMHQML 274
+ L ++K+ + E A S ++ + + E+K + + + + + L
Sbjct: 1655 RKLQAQMKDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQEDL 1703
Score = 49.7 bits (117), Expect = 3e-06
Identities = 54/274 (19%), Positives = 120/274 (43%), Gaps = 12/274 (4%)
Query: 15 KENALDRAEQAEADKKAAEDRSKQLEEDIAAKEKLLRVSEDERDRVLEELHKAED---SL 71
K N + Q E ++ + +D QL+E++ AK+ L R ++ + K +D ++
Sbjct: 1338 KLNVSTKLRQLEEERNSLQD---QLDEEMEAKQNLERHISTLNIQLSDSKKKLQDFASTV 1394
Query: 72 LAAEEAAAKAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIE 131
A EE + + ++ +L ++ + D+ ++ Q+L++ D + + +E
Sbjct: 1395 EALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLE 1454
Query: 132 SRAQK-DEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAEERAELSEGKC 190
+ +K D+ E + I K A + A+ + E K + + LE A E E E
Sbjct: 1455 KKQRKFDQLLAEEKNISSKYADE-RDRAEAEAREKETKALSLARALEEALEAKEELERTN 1513
Query: 191 AELEEELKTVTNNLKSLEAQAEKYSQKEDRYEEEIKVLSDKLKEAETRAEFAERSVTKLE 250
L+ E++ + ++ + + + + E +++ + +L+E E + E + +LE
Sbjct: 1514 KMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQATEDAKLRLE 1573
Query: 251 KSIDDL----EEKVAHAKEENLSMHQMLDQTLLE 280
++ L E + E+N + L + L E
Sbjct: 1574 VNMQALKGQFERDLQARDEQNEEKRRQLQRQLHE 1607
Score = 39.3 bits (90), Expect = 0.004
Identities = 34/114 (29%), Positives = 57/114 (50%), Gaps = 14/114 (12%)
Query: 20 DRAEQAEADKKAAEDRSKQLEEDIAAKEKLLRVSEDERDRVLEELHKAEDSLLAAEEAAA 79
++ EQ +K+AA KQ ++ + KE LL+V EDER + E +K E A
Sbjct: 1835 EQVEQEAREKQAATKSLKQKDKKL--KEILLQV-EDERK--MAEQYK---------EQAE 1880
Query: 80 KAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIESR 133
K A V L R+++ EEE R ++L+EA ++ + R + ++S+
Sbjct: 1881 KGNARVKQLKRQLEEAEEESQRINANRRKLQRELDEATESNEAMGREVNALKSK 1934
>gi|13124875 smooth muscle myosin heavy chain 11 isoform SM2A [Homo
sapiens]
Length = 1938
Score = 82.8 bits (203), Expect = 3e-16
Identities = 58/266 (21%), Positives = 130/266 (48%), Gaps = 15/266 (5%)
Query: 1 MDAIKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEEDIAAKEKLLRVSEDERDRV 60
M +++++ + ++ A++ E K+ E QL+ED+AA E+ + ++ E++ +
Sbjct: 1654 MKDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAERARKQADLEKEEL 1713
Query: 61 LEELHKAEDSLLAAEEAAAKAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAA 120
EEL + A ++ + EA +A L EEEL+ Q + ++ +A + A
Sbjct: 1714 AEELASSLSGRNALQDEKRRLEARIAQL-------EEELEEEQGNMEAMSDRVRKATQQA 1766
Query: 121 DESERGMKVIESRAQKDE---EKMEIQEIQLKEAKHIAEDADR-KYEE----VARKLVII 172
++ + S AQK+E +++E Q +L+ H E A + K++ + K+ +
Sbjct: 1767 EQLSNELATERSTAQKNESARQQLERQNKELRSKLHEMEGAVKSKFKSTIAALEAKIAQL 1826
Query: 173 ESDLERAEERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKEDRYEEEIKVLSDKL 232
E +E+ + + + +++LK + ++ AE+Y ++ ++ +K L +L
Sbjct: 1827 EEQVEQEAREKQAATKSLKQKDKKLKEILLQVEDERKMAEQYKEQAEKGNARVKQLKRQL 1886
Query: 233 KEAETRAEFAERSVTKLEKSIDDLEE 258
+EAE ++ + KL++ +D+ E
Sbjct: 1887 EEAEEESQRINANRRKLQRELDEATE 1912
Score = 71.6 bits (174), Expect = 7e-13
Identities = 61/276 (22%), Positives = 130/276 (47%), Gaps = 21/276 (7%)
Query: 15 KENALDRAEQAEADKKAAEDRSKQLEEDIAAKEKLLRVSEDERDRVLEELHKAEDSLLAA 74
K L + + E + +A ED ++ +E E L+ E + ++ EE + ++ L A
Sbjct: 840 KVKPLLQVTRQEEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAE 899
Query: 75 EEAAAKAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIESRA 134
E A+AE L + Q +EE L + RL + ++ + A+ + ++++
Sbjct: 900 TELYAEAEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQ--AERKKMAQQMLDLEE 957
Query: 135 QKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAEERAELSEGKCAELE 194
Q +EE+ Q++QL++ A+ K +++ ++++++ + + +L LE
Sbjct: 958 QLEEEEAARQKLQLEKVT-----AEAKIKKLEDEILVMDDQNNKLSKERKL-------LE 1005
Query: 195 EELKTVTNNLKSLEAQAEKYSQKEDRYEEEIKVLSDKLKEAETRAEFAERSVTKLE---- 250
E + +T NL E +A+ ++ ++++E I L +LK+ E + E+ KLE
Sbjct: 1006 ERISDLTTNLAEEEEKAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDAS 1065
Query: 251 ---KSIDDLEEKVAHAKEENLSMHQMLDQTLLELNN 283
+ I DL+ ++A K + + L L L++
Sbjct: 1066 DFHEQIADLQAQIAELKMQLAKKEEELQAALARLDD 1101
Score = 70.1 bits (170), Expect = 2e-12
Identities = 68/280 (24%), Positives = 132/280 (47%), Gaps = 24/280 (8%)
Query: 4 IKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEEDIAAK----EKLLRV----SED 55
++K + L+ E + E+ E + +A ED +LE ++ A E+ L+ +E+
Sbjct: 1530 LEKSKRALETQMEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQFERDLQARDEQNEE 1589
Query: 56 ERDRVLEELHKAEDSL-------LAAEEAAAKAEADVASLNRR----IQLVEE---ELDR 101
+R ++ +LH+ E L A A K E D+ L + I+ EE +L +
Sbjct: 1590 KRRQLQRQLHEYETELEDERKQRALAAAAKKKLEGDLKDLELQADSAIKGREEAIKQLRK 1649
Query: 102 AQERLATALQKLEEAEKAADESERGMKVIESRAQKDE-EKMEIQEIQLKEAKHIAEDADR 160
Q ++ ++LE+A + DE K E +A+ E + M++QE L A+ + AD
Sbjct: 1650 LQAQMKDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQE-DLAAAERARKQADL 1708
Query: 161 KYEEVARKLVIIESDLERAEERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKEDR 220
+ EE+A +L S ++ E + A+LEEEL+ N++++ + K +Q+ ++
Sbjct: 1709 EKEELAEELASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQ 1768
Query: 221 YEEEIKVLSDKLKEAETRAEFAERSVTKLEKSIDDLEEKV 260
E+ ++ E+ + ER +L + ++E V
Sbjct: 1769 LSNELATERSTAQKNESARQQLERQNKELRSKLHEMEGAV 1808
Score = 65.5 bits (158), Expect = 5e-11
Identities = 65/270 (24%), Positives = 128/270 (47%), Gaps = 25/270 (9%)
Query: 16 ENALDRAEQAEADKKAAE----DRSKQLEEDIAAKEKLLRVSEDERDRVLEELHKAEDSL 71
E DR +Q +A++K D +QLEE+ AA++KL + E+ ++ K ED +
Sbjct: 932 EEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKL----QLEKVTAEAKIKKLEDEI 987
Query: 72 LAAEEAAAKAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIE 131
L ++ K L++ +L+EE + LA +K + K ++ E + +E
Sbjct: 988 LVMDDQNNK-------LSKERKLLEERISDLTTNLAEEEEKAKNLTKLKNKHESMISELE 1040
Query: 132 SRAQKDEE-KMEIQEIQLKEAKHIAEDADRKYEEVA-RKLVIIESDLERAEERAELSEGK 189
R +K+E+ + E+++++ K + DA +E++A + I E ++ A++ EL +
Sbjct: 1041 VRLKKEEKSRQELEKLKRK----LEGDASDFHEQIADLQAQIAELKMQLAKKEEEL-QAA 1095
Query: 190 CAELEEELKTVTNNLKSLEAQAEKYSQKEDRYEEEIKVLSDKLKEAETRAEFAERSVTKL 249
A L++E+ N LK + S ++ + E + K+ E E T+L
Sbjct: 1096 LARLDDEIAQKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEALKTEL 1155
Query: 250 EKSIDDL---EEKVAHAKEENLSMHQMLDQ 276
E ++D +E A ++E + + LD+
Sbjct: 1156 EDTLDSTATQQELRAKREQEVTVLKKALDE 1185
Score = 65.1 bits (157), Expect = 7e-11
Identities = 71/292 (24%), Positives = 128/292 (43%), Gaps = 27/292 (9%)
Query: 13 LDKENA--------LDRAEQ-AEADKKAAEDRSKQLEEDIAAKEKLLRVSEDERDRVLEE 63
L+KENA L +A+Q E KK E + ++L+ + E+ D+ ++ E
Sbjct: 1229 LEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERARAELNDKVHKLQNE 1288
Query: 64 LHKAEDSLLAAEEAAAKAEADVASLNRRIQLVEEELD---RAQERLATALQKLEEAEKAA 120
+ L AE A K DVASL+ ++Q +E L R + ++T L++LEE +
Sbjct: 1289 VESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEERNSL 1348
Query: 121 -DESERGMKVIESRAQKDEEKMEIQEIQLKEAK----------HIAEDADRKYEEVARKL 169
D+ + M+ Q E + IQL ++K E+ +++++ L
Sbjct: 1349 QDQLDEEMEA----KQNLERHISTLNIQLSDSKKKLQDFASTVEALEEGKKRFQKEIENL 1404
Query: 170 VIIESDLERAEERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKEDRYEEEIKVLS 229
+ A ++ E ++ + + ++L +N + L + EK +K D+ E K +S
Sbjct: 1405 TQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEEKNIS 1464
Query: 230 DKLKEAETRAEFAERSVTKLEKSIDDLEEKVAHAKEENLSMHQMLDQTLLEL 281
K + RAE R S+ E+ AKEE ++ML + +L
Sbjct: 1465 SKYADERDRAEAEAREKETKALSLARALEEALEAKEELERTNKMLKAEMEDL 1516
Score = 64.7 bits (156), Expect = 9e-11
Identities = 70/301 (23%), Positives = 144/301 (47%), Gaps = 36/301 (11%)
Query: 4 IKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEEDIAAKEKLLRVSEDERDRVLEE 63
+K +M+ L K++ + E K+A E + ++++ + E L+ +ED + R+
Sbjct: 1509 LKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQATEDAKLRLEVN 1568
Query: 64 LH----KAEDSLLAAEEAAAKAEADVASLNRRIQLVEEELD--RAQERLATALQK----- 112
+ + E L A +E + E L R++ E EL+ R Q LA A +K
Sbjct: 1569 MQALKGQFERDLQARDE---QNEEKRRQLQRQLHEYETELEDERKQRALAAAAKKKLEGD 1625
Query: 113 LEEAEKAADESERGMKVIESRAQKDEEKMEIQEIQLKEAKH-------IAEDADRKYEEV 165
L++ E AD + +G + + +K + +M+ + +L++A+ A++ ++K + +
Sbjct: 1626 LKDLELQADSAIKGREEAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKENEKKAKSL 1685
Query: 166 ARKLVIIESDLERAEERAELSEGKCAELEEELKTVTNNLKSLEAQAEKY----SQKEDRY 221
L+ ++ DL AE + ++ + EL EEL + + +L+ + + +Q E+
Sbjct: 1686 EADLMQLQEDLAAAERARKQADLEKEELAEELASSLSGRNALQDEKRRLEARIAQLEEEL 1745
Query: 222 EEE---IKVLSDKLKEAETRAE------FAERSVTKLEKSIDDLEEKVAHAKEENLSMHQ 272
EEE ++ +SD++++A +AE ERS + +S E+ KE +H+
Sbjct: 1746 EEEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKNESARQQLER--QNKELRSKLHE 1803
Query: 273 M 273
M
Sbjct: 1804 M 1804
Score = 62.0 bits (149), Expect = 6e-10
Identities = 75/301 (24%), Positives = 133/301 (44%), Gaps = 43/301 (14%)
Query: 7 KMQMLKLDKE--NALDRAEQAEADKKAAEDRSKQLE-------EDIAAK-------EKLL 50
KMQ+ K ++E AL R + A K A + ++LE ED+ ++ EK
Sbjct: 1082 KMQLAKKEEELQAALARLDDEIAQKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQK 1141
Query: 51 RVSEDERDRVLEELHKAEDSLLAAEEAAAKAEADVASLNRRIQLVEEELDRAQERLATAL 110
R +E + + EL DS +E AK E +V L + + +EE + ++
Sbjct: 1142 RDLGEELEALKTELEDTLDSTATQQELRAKREQEVTVLKKAL---DEETRSHEAQVQEMR 1198
Query: 111 QKLEEAEKAADESERGMKVIESRAQKDEEKMEIQEIQLK-------EAKHIAEDADRKYE 163
QK +A + E K ++ K+++ +E + L +AK E +K E
Sbjct: 1199 QKHAQAVEELTEQLEQFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLE 1258
Query: 164 EVARKLVIIESDLERAEERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKEDRYEE 223
++L SD ERA RAEL++ K +L+ E+++VT L E +A K ++
Sbjct: 1259 AQVQELQSKCSDGERA--RAELND-KVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSS 1315
Query: 224 EIKVLSDKLKEAETRAEFAERSVTKLEKSIDDLEEKVAHAKEENLSMHQMLDQTLLELNN 283
+++ + L+E ETR + ++ K+ +EE S+ LD+ + N
Sbjct: 1316 QLQDTQELLQE-ETRQKL-------------NVSTKLRQLEEERNSLQDQLDEEMEAKQN 1361
Query: 284 M 284
+
Sbjct: 1362 L 1362
Score = 61.2 bits (147), Expect = 1e-09
Identities = 58/303 (19%), Positives = 139/303 (45%), Gaps = 35/303 (11%)
Query: 6 KKMQMLKLDKENALD-----------RAEQAEADKKAAEDRSKQLEEDIAAKEKLLRVSE 54
++++ LK + E+ LD R ++ KKA ++ ++ E + + +
Sbjct: 1146 EELEALKTELEDTLDSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAV 1205
Query: 55 DERDRVLEELHKAEDSLLAAEEAAAKAEADVASLNRRIQLVEEELDRAQERLATALQKLE 114
+E LE+ +A+ +L ++ K AD+A R + ++E++ +++L +Q+L
Sbjct: 1206 EELTEQLEQFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQEL- 1264
Query: 115 EAEKAADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIES 174
+ + ER +RA+ +++ ++Q +++ + +A+ K ++A+ + + S
Sbjct: 1265 --QSKCSDGER------ARAELNDKVHKLQN-EVESVTGMLNEAEGKAIKLAKDVASLSS 1315
Query: 175 DLERAEERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKEDRYEEEIKVLS----- 229
L+ +E + + + +L+ + SL+ Q ++ + + E I L+
Sbjct: 1316 QLQDTQELLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSD 1375
Query: 230 --DKLKEAETRAEFAERSVTKLEKSIDDL-----EEKVAHAKEENLS--MHQMLDQTLLE 280
KL++ + E E + +K I++L E+ A+ K E + Q LD +++
Sbjct: 1376 SKKKLQDFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVD 1435
Query: 281 LNN 283
L+N
Sbjct: 1436 LDN 1438
Score = 57.4 bits (137), Expect = 1e-08
Identities = 60/289 (20%), Positives = 135/289 (46%), Gaps = 25/289 (8%)
Query: 1 MDAIKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEEDIAAKEKLLRVSEDERDRV 60
++ K ++Q D LD Q ++ E + ++ ++ +A ++ + DERDR
Sbjct: 1418 LEKTKNRLQQELDDLVVDLDNQRQLVSN---LEKKQRKFDQLLAEEKNISSKYADERDRA 1474
Query: 61 LEELHKAED---SLLAAEEAAAKAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAE 117
E + E SL A E A +A+ ++ N+ ++ E+L +++ + + +LE+++
Sbjct: 1475 EAEAREKETKALSLARALEEALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSK 1534
Query: 118 KAADESERGMKV----IESRAQKDEE---KMEIQEIQLK-----EAKHIAEDADRKYEEV 165
+A + MK +E Q E+ ++E+ LK + + E + K ++
Sbjct: 1535 RALETQMEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQFERDLQARDEQNEEKRRQL 1594
Query: 166 ARKLVIIESDLERAEERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKEDRYEEEI 225
R+L E++LE +ER + + A+ K + +LK LE QA+ + + +++
Sbjct: 1595 QRQLHEYETELE--DERKQRALAAAAK-----KKLEGDLKDLELQADSAIKGREEAIKQL 1647
Query: 226 KVLSDKLKEAETRAEFAERSVTKLEKSIDDLEEKVAHAKEENLSMHQML 274
+ L ++K+ + E A S ++ + + E+K + + + + + L
Sbjct: 1648 RKLQAQMKDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQEDL 1696
Score = 49.7 bits (117), Expect = 3e-06
Identities = 54/274 (19%), Positives = 120/274 (43%), Gaps = 12/274 (4%)
Query: 15 KENALDRAEQAEADKKAAEDRSKQLEEDIAAKEKLLRVSEDERDRVLEELHKAED---SL 71
K N + Q E ++ + +D QL+E++ AK+ L R ++ + K +D ++
Sbjct: 1331 KLNVSTKLRQLEEERNSLQD---QLDEEMEAKQNLERHISTLNIQLSDSKKKLQDFASTV 1387
Query: 72 LAAEEAAAKAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIE 131
A EE + + ++ +L ++ + D+ ++ Q+L++ D + + +E
Sbjct: 1388 EALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLE 1447
Query: 132 SRAQK-DEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAEERAELSEGKC 190
+ +K D+ E + I K A + A+ + E K + + LE A E E E
Sbjct: 1448 KKQRKFDQLLAEEKNISSKYADE-RDRAEAEAREKETKALSLARALEEALEAKEELERTN 1506
Query: 191 AELEEELKTVTNNLKSLEAQAEKYSQKEDRYEEEIKVLSDKLKEAETRAEFAERSVTKLE 250
L+ E++ + ++ + + + + E +++ + +L+E E + E + +LE
Sbjct: 1507 KMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQATEDAKLRLE 1566
Query: 251 KSIDDL----EEKVAHAKEENLSMHQMLDQTLLE 280
++ L E + E+N + L + L E
Sbjct: 1567 VNMQALKGQFERDLQARDEQNEEKRRQLQRQLHE 1600
Score = 39.3 bits (90), Expect = 0.004
Identities = 34/114 (29%), Positives = 57/114 (50%), Gaps = 14/114 (12%)
Query: 20 DRAEQAEADKKAAEDRSKQLEEDIAAKEKLLRVSEDERDRVLEELHKAEDSLLAAEEAAA 79
++ EQ +K+AA KQ ++ + KE LL+V EDER + E +K E A
Sbjct: 1828 EQVEQEAREKQAATKSLKQKDKKL--KEILLQV-EDERK--MAEQYK---------EQAE 1873
Query: 80 KAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIESR 133
K A V L R+++ EEE R ++L+EA ++ + R + ++S+
Sbjct: 1874 KGNARVKQLKRQLEEAEEESQRINANRRKLQRELDEATESNEAMGREVNALKSK 1927
>gi|239745153 PREDICTED: similar to Putative golgin subfamily A
member 6-like protein 6 [Homo sapiens]
Length = 655
Score = 81.6 bits (200), Expect = 7e-16
Identities = 61/269 (22%), Positives = 128/269 (47%), Gaps = 31/269 (11%)
Query: 23 EQAEADKKAAEDRSKQLEEDIAAKEKLLRVSEDERDRVLEELHKAEDSLLAAEEAAAKAE 82
+Q E E++ ++ EE + +E +R E++ R E++H+ E+ + E+ + E
Sbjct: 293 QQQEEKMWRQEEKIQEQEEKMCEQELKIREQEEKMWRQEEKMHEQEEKIREQEDKMWRQE 352
Query: 83 ADVASLNRRIQLVEEELDRAQERLATALQKLEE--------AEKAADE----------SE 124
+ +I+ EE++ R +E++ +K++E EK ++ E
Sbjct: 353 EKIREQEEKIREQEEKMWRQEEKIREQDEKIQEQEEEMWRQEEKIREQEEKRQEKMWRQE 412
Query: 125 RGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAEERAE 184
+ M+ + + ++ EE+M QE +++E + + +D + K EV K+ E ++ EE+ +
Sbjct: 413 KKMREQDEKIREQEEEMWRQEEKIRELEEMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQ 472
Query: 185 LSEGKCAELEEEL----KTVTNNLKSLEAQAEKYSQKEDRYEEEIKV---------LSDK 231
E K E EE+ K + K E + + + Q+E +E+E K+ +K
Sbjct: 473 RQEEKIQEQEEKTWRQEKLLKQEEKIWEQEEKMWRQEEKMWEQEEKMQEQEEKMQRQEEK 532
Query: 232 LKEAETRAEFAERSVTKLEKSIDDLEEKV 260
++E E R E + + E + +LEE++
Sbjct: 533 MREQEVRLWQQEEKMQEQEVRLQELEERL 561
Score = 77.0 bits (188), Expect = 2e-14
Identities = 60/256 (23%), Positives = 123/256 (48%), Gaps = 23/256 (8%)
Query: 24 QAEADKKAAEDRSKQLEEDIAAKEKLLRVSEDERDRVLEELHKAEDSLLAAEEAAAKAEA 83
+ E + E++ + EE + +E+ +R ED+ R E++ + E+ + EE + E
Sbjct: 315 EQELKIREQEEKMWRQEEKMHEQEEKIREQEDKMWRQEEKIREQEEKIREQEEKMWRQEE 374
Query: 84 DVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIESRAQKDEEKMEI 143
+ + +IQ EEE+ R +E++ ++ E+ ++ E+ M+ + + ++ EE+M
Sbjct: 375 KIREQDEKIQEQEEEMWRQEEKIR---EQEEKRQEKMWRQEKKMREQDEKIREQEEEMWR 431
Query: 144 QEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAEERAELSEGKCAELEEELKTVTNN 203
QE +++E + + +D + K EV K+ E ++ EE+ + E K E EE+
Sbjct: 432 QEEKIRELEEMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQRQEEKIQEQEEKTWRQEKL 491
Query: 204 LKSLEA-----------------QAEKYSQKED---RYEEEIKVLSDKLKEAETRAEFAE 243
LK E Q EK ++E+ R EE+++ +L + E + + E
Sbjct: 492 LKQEEKIWEQEEKMWRQEEKMWEQEEKMQEQEEKMQRQEEKMREQEVRLWQQEEKMQEQE 551
Query: 244 RSVTKLEKSIDDLEEK 259
+ +LE+ + L +K
Sbjct: 552 VRLQELEERLGKLGQK 567
Score = 73.6 bits (179), Expect = 2e-13
Identities = 61/246 (24%), Positives = 120/246 (48%), Gaps = 19/246 (7%)
Query: 37 KQLEEDIAAKEKLLRVSEDERDRV---LEEL-HKAEDSLLAAEEAAAKAEAD-----VAS 87
++L+E A ++ LR+ E E+ + +++L K E + L + + EAD + S
Sbjct: 214 EELKEKNAELQEKLRLVESEKSEIQLNVKDLKRKLERAQLLLPQQQLQVEADRLGKELQS 273
Query: 88 LNRRIQLVEEELD-------RAQERLATALQKLEEAEKAADESERGMKVIESRAQKDEEK 140
++ ++Q EE + + +E++ +K++E E+ E E ++ E + + EEK
Sbjct: 274 VSAKLQAQVEENELWNLLNQQQEEKMWRQEEKIQEQEEKMCEQELKIREQEEKMWRQEEK 333
Query: 141 MEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAEERAELSEGKCAELEEELKTV 200
M QE +++E + + K E K+ E + R EE+ + K E EEE+
Sbjct: 334 MHEQEEKIREQEDKMWRQEEKIREQEEKIREQEEKMWRQEEKIREQDEKIQEQEEEM--- 390
Query: 201 TNNLKSLEAQAEKYSQKEDRYEEEIKVLSDKLKEAETRAEFAERSVTKLEKSIDDLEEKV 260
+ + Q EK +K R E++++ +K++E E E + +LE+ + D EEK+
Sbjct: 391 WRQEEKIREQEEKRQEKMWRQEKKMREQDEKIREQEEEMWRQEEKIRELEEMMQDQEEKL 450
Query: 261 AHAKEE 266
+E+
Sbjct: 451 REVEEK 456
Score = 73.2 bits (178), Expect = 2e-13
Identities = 69/286 (24%), Positives = 136/286 (47%), Gaps = 31/286 (10%)
Query: 1 MDAIKKKMQMLKLDKENALDRAE--------QAEADKKAAEDRSKQLEEDIAAKEKLLRV 52
+++ K ++Q+ D + L+RA+ Q EAD+ E +S ++AK + +V
Sbjct: 230 VESEKSEIQLNVKDLKRKLERAQLLLPQQQLQVEADRLGKELQS------VSAKLQA-QV 282
Query: 53 SEDERDRVLEELHKAEDSLLAAEEAAAKAEADVASLNRRIQLVEEELDRAQERLATALQK 112
E+E +L + + E+ + EE + E + +I+ EE++ R +E++ +K
Sbjct: 283 EENELWNLLNQ--QQEEKMWRQEEKIQEQEEKMCEQELKIREQEEKMWRQEEKMHEQEEK 340
Query: 113 LEEAEKAADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVII 172
+ E E E ++ E + ++ EEKM QE +++E E + EE+ R+ I
Sbjct: 341 IREQEDKMWRQEEKIREQEEKIREQEEKMWRQEEKIREQD---EKIQEQEEEMWRQEEKI 397
Query: 173 ESDLERAEERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKED--RYEEEIKVLSD 230
E+ +E+ E K E +E+++ E + E + Q+E EE ++ +
Sbjct: 398 REQEEKRQEKMWRQEKKMREQDEKIR---------EQEEEMWRQEEKIRELEEMMQDQEE 448
Query: 231 KLKEAETRAEFAERSVTKLEKSIDDLEEKVAHAKEENLSMHQMLDQ 276
KL+E E + + E + + E+ I EEK+ +E+ ++L Q
Sbjct: 449 KLREVEEKMQEEEEKMQEQEEKIQRQEEKIQEQEEKTWRQEKLLKQ 494
Score = 68.9 bits (167), Expect = 5e-12
Identities = 57/226 (25%), Positives = 111/226 (49%), Gaps = 8/226 (3%)
Query: 6 KKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEEDIAAKEKLLRVSEDERDRVLEELH 65
++ + ++ +E ++ + E + +++ ++ EE++ +E+ +R E+ E+L
Sbjct: 392 RQEEKIREQEEKRQEKMWRQEKKMREQDEKIREQEEEMWRQEEKIRELEEMMQDQEEKLR 451
Query: 66 KAEDSLLAAEEAAAKAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESER 125
+ E+ + EE + E + +IQ EE+ R QE+L +K+ E E+ E
Sbjct: 452 EVEEKMQEEEEKMQEQEEKIQRQEEKIQEQEEKTWR-QEKLLKQEEKIWEQEEKMWRQEE 510
Query: 126 GMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAEERAEL 185
M E + Q+ EEKM+ QE +++E + + K +E +L +E L + ++AEL
Sbjct: 511 KMWEQEEKMQEQEEKMQRQEEKMREQEVRLWQQEEKMQEQEVRLQELEERLGKLGQKAEL 570
Query: 186 SEGKCAEL-EEELKTVTN----NLKSLEAQAEKYSQKEDRYEEEIK 226
G E + L T+T LKS EAQ+ Q++D Y ++
Sbjct: 571 LGGAGRESGSQRLPTLTPILQVELKSQEAQS--LQQQQDHYRGHLQ 614
Score = 68.6 bits (166), Expect = 6e-12
Identities = 54/227 (23%), Positives = 111/227 (48%), Gaps = 9/227 (3%)
Query: 20 DRAEQAEADKKAAEDRSKQLEEDIAAKEKLLRVSEDERDRVLEELHKAEDSLLAAEEAAA 79
D+ + E + E++ ++ EE + +E+ +R +++ EE+ + E+ + EE
Sbjct: 346 DKMWRQEEKIREQEEKIREQEEKMWRQEEKIREQDEKIQEQEEEMWRQEEKIREQEEKRQ 405
Query: 80 ----KAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIESRAQ 135
+ E + + +I+ EEE+ R +E++ + +++ E+ E E M+ E + Q
Sbjct: 406 EKMWRQEKKMREQDEKIREQEEEMWRQEEKIRELEEMMQDQEEKLREVEEKMQEEEEKMQ 465
Query: 136 KDEEKMEIQE--IQLKEAKHIAEDADRKYEEVARKLVIIESDLERAEERAELSEGKCAEL 193
+ EEK++ QE IQ +E K ++ K EE K+ E + R EE+ E K E
Sbjct: 466 EQEEKIQRQEEKIQEQEEKTWRQEKLLKQEE---KIWEQEEKMWRQEEKMWEQEEKMQEQ 522
Query: 194 EEELKTVTNNLKSLEAQAEKYSQKEDRYEEEIKVLSDKLKEAETRAE 240
EE+++ ++ E + + +K E ++ L ++L + +AE
Sbjct: 523 EEKMQRQEEKMREQEVRLWQQEEKMQEQEVRLQELEERLGKLGQKAE 569
Score = 67.8 bits (164), Expect = 1e-11
Identities = 51/227 (22%), Positives = 112/227 (49%), Gaps = 12/227 (5%)
Query: 2 DAIKKKMQMLKLDKENALDRAEQA---EADKKAAEDRSKQLEEDIAAKEKLLRVSEDERD 58
D + ++ + ++ +E ++ E+ E + +++ ++ EE++ +E+ +R E++R
Sbjct: 346 DKMWRQEEKIREQEEKIREQEEKMWRQEEKIREQDEKIQEQEEEMWRQEEKIREQEEKRQ 405
Query: 59 RVLEELHKAEDSLLAAEEAAAKAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEK 118
E++ + E + +E + E ++ +I+ +EE + +E+L +K++E E+
Sbjct: 406 ---EKMWRQEKKMREQDEKIREQEEEMWRQEEKIRELEEMMQDQEEKLREVEEKMQEEEE 462
Query: 119 AADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADR------KYEEVARKLVII 172
E E ++ E + Q+ EEK QE LK+ + I E ++ K E K+
Sbjct: 463 KMQEQEEKIQRQEEKIQEQEEKTWRQEKLLKQEEKIWEQEEKMWRQEEKMWEQEEKMQEQ 522
Query: 173 ESDLERAEERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKED 219
E ++R EE+ E + + EE+++ L+ LE + K QK +
Sbjct: 523 EEKMQRQEEKMREQEVRLWQQEEKMQEQEVRLQELEERLGKLGQKAE 569
Score = 42.0 bits (97), Expect = 6e-04
Identities = 59/285 (20%), Positives = 126/285 (44%), Gaps = 36/285 (12%)
Query: 5 KKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEEDIAAKEKLLRVSEDERDRVLEEL 64
+K+ + D+++ L+ +E ++ K++ + + L +D A ++ + + D V
Sbjct: 76 RKRRGTKRWDEDDDLEESEDSKQCKESLKRVTFTLPDDEAIEDAGVSHVKKNSDEVKSSF 135
Query: 65 HKAEDSLLAAEEAAAKAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESE 124
K ++ + K V ++L E AQ+R +L LEE
Sbjct: 136 KKRQEKMNEKNYTFRKR---VVIKKPWLRLGEVT---AQKRPENSL--LEETLHFDHAVR 187
Query: 125 RGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIES---------- 174
G + + ++D +E+ + + E+ K E+ KL ++ES
Sbjct: 188 MGTYIEKLTKERDAPSLELYRNTITD-----EELKEKNAELQEKLRLVESEKSEIQLNVK 242
Query: 175 DLERAEERAEL------SEGKCAELEEELKTVTNNLKSLEAQAEKYS----QKED---RY 221
DL+R ERA+L + + L +EL++V+ L++ + E ++ Q+E+ R
Sbjct: 243 DLKRKLERAQLLLPQQQLQVEADRLGKELQSVSAKLQAQVEENELWNLLNQQQEEKMWRQ 302
Query: 222 EEEIKVLSDKLKEAETRAEFAERSVTKLEKSIDDLEEKVAHAKEE 266
EE+I+ +K+ E E + E + + E+ + + EEK+ +++
Sbjct: 303 EEKIQEQEEKMCEQELKIREQEEKMWRQEEKMHEQEEKIREQEDK 347
>gi|239745127 PREDICTED: similar to Putative golgin subfamily A
member 6-like protein 6 [Homo sapiens]
Length = 655
Score = 81.6 bits (200), Expect = 7e-16
Identities = 61/269 (22%), Positives = 128/269 (47%), Gaps = 31/269 (11%)
Query: 23 EQAEADKKAAEDRSKQLEEDIAAKEKLLRVSEDERDRVLEELHKAEDSLLAAEEAAAKAE 82
+Q E E++ ++ EE + +E +R E++ R E++H+ E+ + E+ + E
Sbjct: 293 QQQEEKMWRQEEKIQEQEEKMCEQELKIREQEEKMWRQEEKMHEQEEKIREQEDKMWRQE 352
Query: 83 ADVASLNRRIQLVEEELDRAQERLATALQKLEE--------AEKAADE----------SE 124
+ +I+ EE++ R +E++ +K++E EK ++ E
Sbjct: 353 EKIREQEEKIREQEEKMWRQEEKIREQDEKIQEQEEEMWRQEEKIREQEEKRQEKMWRQE 412
Query: 125 RGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAEERAE 184
+ M+ + + ++ EE+M QE +++E + + +D + K EV K+ E ++ EE+ +
Sbjct: 413 KKMREQDEKIREQEEEMWRQEEKIRELEEMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQ 472
Query: 185 LSEGKCAELEEEL----KTVTNNLKSLEAQAEKYSQKEDRYEEEIKV---------LSDK 231
E K E EE+ K + K E + + + Q+E +E+E K+ +K
Sbjct: 473 RQEEKIQEQEEKTWRQEKLLKQEEKIWEQEEKMWRQEEKMWEQEEKMQEQEEKMQRQEEK 532
Query: 232 LKEAETRAEFAERSVTKLEKSIDDLEEKV 260
++E E R E + + E + +LEE++
Sbjct: 533 MREQEVRLWQQEEKMQEQEVRLQELEERL 561
Score = 77.0 bits (188), Expect = 2e-14
Identities = 60/256 (23%), Positives = 123/256 (48%), Gaps = 23/256 (8%)
Query: 24 QAEADKKAAEDRSKQLEEDIAAKEKLLRVSEDERDRVLEELHKAEDSLLAAEEAAAKAEA 83
+ E + E++ + EE + +E+ +R ED+ R E++ + E+ + EE + E
Sbjct: 315 EQELKIREQEEKMWRQEEKMHEQEEKIREQEDKMWRQEEKIREQEEKIREQEEKMWRQEE 374
Query: 84 DVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIESRAQKDEEKMEI 143
+ + +IQ EEE+ R +E++ ++ E+ ++ E+ M+ + + ++ EE+M
Sbjct: 375 KIREQDEKIQEQEEEMWRQEEKIR---EQEEKRQEKMWRQEKKMREQDEKIREQEEEMWR 431
Query: 144 QEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAEERAELSEGKCAELEEELKTVTNN 203
QE +++E + + +D + K EV K+ E ++ EE+ + E K E EE+
Sbjct: 432 QEEKIRELEEMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQRQEEKIQEQEEKTWRQEKL 491
Query: 204 LKSLEA-----------------QAEKYSQKED---RYEEEIKVLSDKLKEAETRAEFAE 243
LK E Q EK ++E+ R EE+++ +L + E + + E
Sbjct: 492 LKQEEKIWEQEEKMWRQEEKMWEQEEKMQEQEEKMQRQEEKMREQEVRLWQQEEKMQEQE 551
Query: 244 RSVTKLEKSIDDLEEK 259
+ +LE+ + L +K
Sbjct: 552 VRLQELEERLGKLGQK 567
Score = 73.6 bits (179), Expect = 2e-13
Identities = 61/246 (24%), Positives = 120/246 (48%), Gaps = 19/246 (7%)
Query: 37 KQLEEDIAAKEKLLRVSEDERDRV---LEEL-HKAEDSLLAAEEAAAKAEAD-----VAS 87
++L+E A ++ LR+ E E+ + +++L K E + L + + EAD + S
Sbjct: 214 EELKEKNAELQEKLRLVESEKSEIQLNVKDLKRKLERAQLLLPQQQLQVEADRLGKELQS 273
Query: 88 LNRRIQLVEEELD-------RAQERLATALQKLEEAEKAADESERGMKVIESRAQKDEEK 140
++ ++Q EE + + +E++ +K++E E+ E E ++ E + + EEK
Sbjct: 274 VSAKLQAQVEENELWNLLNQQQEEKMWRQEEKIQEQEEKMCEQELKIREQEEKMWRQEEK 333
Query: 141 MEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAEERAELSEGKCAELEEELKTV 200
M QE +++E + + K E K+ E + R EE+ + K E EEE+
Sbjct: 334 MHEQEEKIREQEDKMWRQEEKIREQEEKIREQEEKMWRQEEKIREQDEKIQEQEEEM--- 390
Query: 201 TNNLKSLEAQAEKYSQKEDRYEEEIKVLSDKLKEAETRAEFAERSVTKLEKSIDDLEEKV 260
+ + Q EK +K R E++++ +K++E E E + +LE+ + D EEK+
Sbjct: 391 WRQEEKIREQEEKRQEKMWRQEKKMREQDEKIREQEEEMWRQEEKIRELEEMMQDQEEKL 450
Query: 261 AHAKEE 266
+E+
Sbjct: 451 REVEEK 456
Score = 73.2 bits (178), Expect = 2e-13
Identities = 69/286 (24%), Positives = 136/286 (47%), Gaps = 31/286 (10%)
Query: 1 MDAIKKKMQMLKLDKENALDRAE--------QAEADKKAAEDRSKQLEEDIAAKEKLLRV 52
+++ K ++Q+ D + L+RA+ Q EAD+ E +S ++AK + +V
Sbjct: 230 VESEKSEIQLNVKDLKRKLERAQLLLPQQQLQVEADRLGKELQS------VSAKLQA-QV 282
Query: 53 SEDERDRVLEELHKAEDSLLAAEEAAAKAEADVASLNRRIQLVEEELDRAQERLATALQK 112
E+E +L + + E+ + EE + E + +I+ EE++ R +E++ +K
Sbjct: 283 EENELWNLLNQ--QQEEKMWRQEEKIQEQEEKMCEQELKIREQEEKMWRQEEKMHEQEEK 340
Query: 113 LEEAEKAADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVII 172
+ E E E ++ E + ++ EEKM QE +++E E + EE+ R+ I
Sbjct: 341 IREQEDKMWRQEEKIREQEEKIREQEEKMWRQEEKIREQD---EKIQEQEEEMWRQEEKI 397
Query: 173 ESDLERAEERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKED--RYEEEIKVLSD 230
E+ +E+ E K E +E+++ E + E + Q+E EE ++ +
Sbjct: 398 REQEEKRQEKMWRQEKKMREQDEKIR---------EQEEEMWRQEEKIRELEEMMQDQEE 448
Query: 231 KLKEAETRAEFAERSVTKLEKSIDDLEEKVAHAKEENLSMHQMLDQ 276
KL+E E + + E + + E+ I EEK+ +E+ ++L Q
Sbjct: 449 KLREVEEKMQEEEEKMQEQEEKIQRQEEKIQEQEEKTWRQEKLLKQ 494
Score = 68.9 bits (167), Expect = 5e-12
Identities = 57/226 (25%), Positives = 111/226 (49%), Gaps = 8/226 (3%)
Query: 6 KKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEEDIAAKEKLLRVSEDERDRVLEELH 65
++ + ++ +E ++ + E + +++ ++ EE++ +E+ +R E+ E+L
Sbjct: 392 RQEEKIREQEEKRQEKMWRQEKKMREQDEKIREQEEEMWRQEEKIRELEEMMQDQEEKLR 451
Query: 66 KAEDSLLAAEEAAAKAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESER 125
+ E+ + EE + E + +IQ EE+ R QE+L +K+ E E+ E
Sbjct: 452 EVEEKMQEEEEKMQEQEEKIQRQEEKIQEQEEKTWR-QEKLLKQEEKIWEQEEKMWRQEE 510
Query: 126 GMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAEERAEL 185
M E + Q+ EEKM+ QE +++E + + K +E +L +E L + ++AEL
Sbjct: 511 KMWEQEEKMQEQEEKMQRQEEKMREQEVRLWQQEEKMQEQEVRLQELEERLGKLGQKAEL 570
Query: 186 SEGKCAEL-EEELKTVTN----NLKSLEAQAEKYSQKEDRYEEEIK 226
G E + L T+T LKS EAQ+ Q++D Y ++
Sbjct: 571 LGGAGRESGSQRLPTLTPILQVELKSQEAQS--LQQQQDHYRGHLQ 614
Score = 68.6 bits (166), Expect = 6e-12
Identities = 54/227 (23%), Positives = 111/227 (48%), Gaps = 9/227 (3%)
Query: 20 DRAEQAEADKKAAEDRSKQLEEDIAAKEKLLRVSEDERDRVLEELHKAEDSLLAAEEAAA 79
D+ + E + E++ ++ EE + +E+ +R +++ EE+ + E+ + EE
Sbjct: 346 DKMWRQEEKIREQEEKIREQEEKMWRQEEKIREQDEKIQEQEEEMWRQEEKIREQEEKRQ 405
Query: 80 ----KAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIESRAQ 135
+ E + + +I+ EEE+ R +E++ + +++ E+ E E M+ E + Q
Sbjct: 406 EKMWRQEKKMREQDEKIREQEEEMWRQEEKIRELEEMMQDQEEKLREVEEKMQEEEEKMQ 465
Query: 136 KDEEKMEIQE--IQLKEAKHIAEDADRKYEEVARKLVIIESDLERAEERAELSEGKCAEL 193
+ EEK++ QE IQ +E K ++ K EE K+ E + R EE+ E K E
Sbjct: 466 EQEEKIQRQEEKIQEQEEKTWRQEKLLKQEE---KIWEQEEKMWRQEEKMWEQEEKMQEQ 522
Query: 194 EEELKTVTNNLKSLEAQAEKYSQKEDRYEEEIKVLSDKLKEAETRAE 240
EE+++ ++ E + + +K E ++ L ++L + +AE
Sbjct: 523 EEKMQRQEEKMREQEVRLWQQEEKMQEQEVRLQELEERLGKLGQKAE 569
Score = 67.8 bits (164), Expect = 1e-11
Identities = 51/227 (22%), Positives = 112/227 (49%), Gaps = 12/227 (5%)
Query: 2 DAIKKKMQMLKLDKENALDRAEQA---EADKKAAEDRSKQLEEDIAAKEKLLRVSEDERD 58
D + ++ + ++ +E ++ E+ E + +++ ++ EE++ +E+ +R E++R
Sbjct: 346 DKMWRQEEKIREQEEKIREQEEKMWRQEEKIREQDEKIQEQEEEMWRQEEKIREQEEKRQ 405
Query: 59 RVLEELHKAEDSLLAAEEAAAKAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEK 118
E++ + E + +E + E ++ +I+ +EE + +E+L +K++E E+
Sbjct: 406 ---EKMWRQEKKMREQDEKIREQEEEMWRQEEKIRELEEMMQDQEEKLREVEEKMQEEEE 462
Query: 119 AADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADR------KYEEVARKLVII 172
E E ++ E + Q+ EEK QE LK+ + I E ++ K E K+
Sbjct: 463 KMQEQEEKIQRQEEKIQEQEEKTWRQEKLLKQEEKIWEQEEKMWRQEEKMWEQEEKMQEQ 522
Query: 173 ESDLERAEERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKED 219
E ++R EE+ E + + EE+++ L+ LE + K QK +
Sbjct: 523 EEKMQRQEEKMREQEVRLWQQEEKMQEQEVRLQELEERLGKLGQKAE 569
Score = 41.2 bits (95), Expect = 0.001
Identities = 59/285 (20%), Positives = 126/285 (44%), Gaps = 36/285 (12%)
Query: 5 KKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEEDIAAKEKLLRVSEDERDRVLEEL 64
+K+ + D+++ L+ +E ++ K++ + + L +D A ++ + + D V
Sbjct: 76 RKRRGTKRWDEDDDLEESEDSKQCKESLKRVTFTLPDDEAIEDAGVSHVKKNSDEVKSSF 135
Query: 65 HKAEDSLLAAEEAAAKAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESE 124
K ++ + K V ++L E AQ+R +L LEE
Sbjct: 136 KKRQEKMNEKNYTFRKR---VVIKKPWLRLGEVT---AQKRPENSL--LEETLHFDHAVR 187
Query: 125 RGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIES---------- 174
G + + ++D +E+ + + E+ K E+ KL ++ES
Sbjct: 188 MGTYIEKLTKERDALSLELYRNTITD-----EELKEKNAELQEKLRLVESEKSEIQLNVK 242
Query: 175 DLERAEERAEL------SEGKCAELEEELKTVTNNLKSLEAQAEKYS----QKED---RY 221
DL+R ERA+L + + L +EL++V+ L++ + E ++ Q+E+ R
Sbjct: 243 DLKRKLERAQLLLPQQQLQVEADRLGKELQSVSAKLQAQVEENELWNLLNQQQEEKMWRQ 302
Query: 222 EEEIKVLSDKLKEAETRAEFAERSVTKLEKSIDDLEEKVAHAKEE 266
EE+I+ +K+ E E + E + + E+ + + EEK+ +++
Sbjct: 303 EEKIQEQEEKMCEQELKIREQEEKMWRQEEKMHEQEEKIREQEDK 347
>gi|46049114 M-phase phosphoprotein 1 [Homo sapiens]
Length = 1780
Score = 80.9 bits (198), Expect = 1e-15
Identities = 62/272 (22%), Positives = 135/272 (49%), Gaps = 24/272 (8%)
Query: 6 KKMQMLKLDKENALDRA-----EQAEADKKAAEDRSKQLEEDIAAKEKL---LRVSEDER 57
K+ ++ + ++EN+ + E+ + KA+ +S Q+EE EKL ++ +DE
Sbjct: 1000 KEYRIQEPNRENSFHSSIEAIWEECKEIVKASSKKSHQIEELEQQIEKLQAEVKGYKDEN 1059
Query: 58 DRVLEELHKAEDSLLAAEEAAAKAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAE 117
+R+ E+ HK +D LL +E IQ ++EEL L +Q + E +
Sbjct: 1060 NRLKEKEHKNQDDLLKEKETL-------------IQQLKEELQEKNVTLDVQIQHVVEGK 1106
Query: 118 KAADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYE---EVARKLVIIES 174
+A E +G+ +++ ++ E +E Q+++ + + +D K ++ R L +
Sbjct: 1107 RALSELTQGVTCYKAKIKELETILETQKVECSHSAKLEQDILEKESIILKLERNLKEFQE 1166
Query: 175 DLERAEERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKEDRYEEEIKVLSDKLKE 234
L+ + + + K +L+EE+ +TNNL+ ++ + ++E+ +E + L ++L
Sbjct: 1167 HLQDSVKNTKDLNVKELKLKEEITQLTNNLQDMKHLLQLKEEEEETNRQETEKLKEELSA 1226
Query: 235 AETRAEFAERSVTKLEKSIDDLEEKVAHAKEE 266
+ R + + + + E+ DL+EK+ AK++
Sbjct: 1227 SSARTQNLKADLQRKEEDYADLKEKLTDAKKQ 1258
Score = 57.0 bits (136), Expect = 2e-08
Identities = 58/304 (19%), Positives = 129/304 (42%), Gaps = 31/304 (10%)
Query: 2 DAIKKKMQMLKLDK---------ENALDRAEQAEADKKAAEDRSKQLEEDIAAKEKLLRV 52
D ++K+ +LKL++ ++++ + + ++ QL ++ + LL++
Sbjct: 1146 DILEKESIILKLERNLKEFQEHLQDSVKNTKDLNVKELKLKEEITQLTNNLQDMKHLLQL 1205
Query: 53 SEDERDRVLEELHKAEDSLLAAEEAAAKAEADVASLNRRIQLVEEELDRAQERLATALQK 112
E+E + +E K ++ L A+ +AD +Q EE+ +E+L A ++
Sbjct: 1206 KEEEEETNRQETEKLKEELSASSARTQNLKAD-------LQRKEEDYADLKEKLTDAKKQ 1258
Query: 113 LEEAEKAADESERGMKVIESRAQKDEEKME------------IQEIQLKEAKHIAEDADR 160
+++ +K K++ + + E+K IQ+++ + E+A +
Sbjct: 1259 IKQVQKEVSVMRDEDKLLRIKINELEKKKNQCSQELDMKQRTIQQLKEQLNNQKVEEAIQ 1318
Query: 161 KYEEVARKLVIIESDLERAEERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKEDR 220
+YE + L + E +E E E E ++ L+ ++ L + EK+ +K +
Sbjct: 1319 QYERACKDLNVKEKIIEDMRMTLEEQEQTQVEQDQVLEAKLEEVERLATELEKWKEKCND 1378
Query: 221 YEEEIKVLSDKLKEAETRAEFAERSVTKLEKSIDDLEEKVAHAKEENLSMHQMLDQTLLE 280
E + S+K E T +T L+ + + E+K +++ L ML E
Sbjct: 1379 LETKNNQRSNKEHENNTD---VLGKLTNLQDELQESEQKYNADRKKWLEEKMMLITQAKE 1435
Query: 281 LNNM 284
N+
Sbjct: 1436 AENI 1439
Score = 47.4 bits (111), Expect = 1e-05
Identities = 60/284 (21%), Positives = 120/284 (42%), Gaps = 24/284 (8%)
Query: 2 DAIKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEEDIAAKEKLL-RVSEDERDRV 60
D+ K K EN L + E KK + S + ED E++ ++E E RV
Sbjct: 782 DSKSKICSERKRVNENELQQDEPPA--KKGSIHVSSAITEDQKKSEEVRPNIAEIEDIRV 839
Query: 61 LEELHKAEDSLLAAEEAAAKAEADV-ASLNRRIQLVEEELDRAQERLATALQKLEEAEKA 119
L+E ++ + L E K E + A LN++I ++EL ++++ T +++++ +
Sbjct: 840 LQENNEGLRAFLLTIENELKNEKEEKAELNKQIVHFQQELSLSEKKNLTLSKEVQQIQSN 899
Query: 120 ADESERGMKVIESRAQKDEEKM----------------EIQEIQLKEAKHIAEDADRKYE 163
D + + V +S+ Q+ EEK+ + +I+L K
Sbjct: 900 YDIAIAELHVQKSKNQEQEEKIMKLSNEIETATRSITNNVSQIKLMHTKIDELRTLDSVS 959
Query: 164 EVARKLVIIESDLERAEERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKEDRYEE 223
+++ ++ DL E L + L + V+ +K Q +E+ +
Sbjct: 960 QISNIDLLNLRDLSNGSEEDNLPNTQLDLLGNDY-LVSKQVKEYRIQE---PNRENSFHS 1015
Query: 224 EIKVLSDKLKEAETRAEFAERSVTKLEKSIDDLEEKVAHAKEEN 267
I+ + ++ KE + + +LE+ I+ L+ +V K+EN
Sbjct: 1016 SIEAIWEECKEIVKASSKKSHQIEELEQQIEKLQAEVKGYKDEN 1059
Score = 46.6 bits (109), Expect = 2e-05
Identities = 66/303 (21%), Positives = 135/303 (44%), Gaps = 39/303 (12%)
Query: 5 KKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEEDIAAKEKLLRVSEDERDRVLEEL 64
K K +++K KE R ++++ + E +K++ ++L+ + D+++ + E
Sbjct: 686 KTKGELIKT-KEELKKRENESDSLIQELETSNKKIITQNQRIKELINII-DQKEDTINEF 743
Query: 65 HKAEDSLLAAEEAAAKAEADVASLNRRI---QLVEEELDRAQERLATALQKLEEAEKAAD 121
+ + + KA+ +N ++ + VE D ++ ++ + +++ E E D
Sbjct: 744 QNLKSHMENTFKCNDKADTSSLIINNKLICNETVEVPKD-SKSKICSERKRVNENELQQD 802
Query: 122 E--SERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERA 179
E +++G + S +D++K E + E + I + E + L+ IE++L+
Sbjct: 803 EPPAKKGSIHVSSAITEDQKKSEEVRPNIAEIEDIRVLQENN-EGLRAFLLTIENELKNE 861
Query: 180 -EERAEL-------------SEGKCAELEEELKTVTNNLKSLEAQAEKYSQKEDRYEEEI 225
EE+AEL SE K L +E++ + +N A+ K EE+I
Sbjct: 862 KEEKAELNKQIVHFQQELSLSEKKNLTLSKEVQQIQSNYDIAIAELHVQKSKNQEQEEKI 921
Query: 226 KVLSDKLKEAETRAEFAERSVTKLEKSIDDLEEKVAHAKEENL----SMHQMLDQTLLEL 281
LS+++ E A RS+T I K+ H K + L S+ Q+ + LL L
Sbjct: 922 MKLSNEI-------ETATRSITNNVSQI-----KLMHTKIDELRTLDSVSQISNIDLLNL 969
Query: 282 NNM 284
++
Sbjct: 970 RDL 972
Score = 34.3 bits (77), Expect = 0.13
Identities = 45/243 (18%), Positives = 97/243 (39%), Gaps = 52/243 (21%)
Query: 36 SKQLEEDIAAKEKLLRVSEDERDRVLEELHKAEDSLLAAEEAAAKAEADVASLNRRIQLV 95
S+ + D + K+L V R + + L+ E+ + E + N +L+
Sbjct: 499 SQDVSLDSNSNSKILNVK-----RATISWENSLEDLMEDEDLVEELENAEETQNVETKLL 553
Query: 96 EEELDR---------AQERLATALQKLEEAEKAADESERGMKVIESRAQKD--------- 137
+E+LD+ + E L +E+ +K ++ +E + +++
Sbjct: 554 DEDLDKTLEENKAFISHEEKRKLLDLIEDLKKKLINEKKEKLTLEFKIREEVTQEFTQYW 613
Query: 138 -EEKMEIQEIQLKEAKHIAEDADRKY-------------EEVARKLVIIESDLERAEERA 183
+ + + +E L+E + + E+A+R+ EE A+ + + + E A
Sbjct: 614 AQREADFKETLLQEREILEENAERRLAIFKDLVGKCDTREEAAKDICATKVETEEATACL 673
Query: 184 EL-----------SEGKCAELEEELKTVTNN----LKSLEAQAEKYSQKEDRYEEEIKVL 228
EL ++G+ + +EELK N ++ LE +K + R +E I ++
Sbjct: 674 ELKFNQIKAELAKTKGELIKTKEELKKRENESDSLIQELETSNKKIITQNQRIKELINII 733
Query: 229 SDK 231
K
Sbjct: 734 DQK 736
Score = 30.4 bits (67), Expect = 1.8
Identities = 23/90 (25%), Positives = 43/90 (47%), Gaps = 5/90 (5%)
Query: 186 SEGKCAELEEELKTVTNNLKSL---EAQAEKYSQKEDRYEEEIKVLSDKLKEA--ETRAE 240
S K ++ + N+L+ L E E+ E+ E K+L + L + E +A
Sbjct: 508 SNSKILNVKRATISWENSLEDLMEDEDLVEELENAEETQNVETKLLDEDLDKTLEENKAF 567
Query: 241 FAERSVTKLEKSIDDLEEKVAHAKEENLSM 270
+ KL I+DL++K+ + K+E L++
Sbjct: 568 ISHEEKRKLLDLIEDLKKKLINEKKEKLTL 597
>gi|41406064 myosin, heavy polypeptide 10, non-muscle [Homo sapiens]
Length = 1976
Score = 80.5 bits (197), Expect = 2e-15
Identities = 61/266 (22%), Positives = 121/266 (45%), Gaps = 15/266 (5%)
Query: 1 MDAIKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEEDIAAKEKLLRVSEDERDRV 60
M +++++ + ++ +++++E K+ E QL+E++A+ E+ R +E ERD +
Sbjct: 1654 MKDYQRELEEARASRDEIFAQSKESEKKLKSLEAEILQLQEELASSERARRHAEQERDEL 1713
Query: 61 LEELHKAEDSLLAAEEAAAKAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAA 120
+E+ + A + + EA +A L EEEL+ Q + + +
Sbjct: 1714 ADEITNSASGKSALLDEKRRLEARIAQL-------EEELEEEQSNMELLNDRFRKTTLQV 1766
Query: 121 DESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLV-IIESDLERA 179
D + S AQK + + E Q KE K ++ + + + + +E+ + +
Sbjct: 1767 DTLNAELAAERSAAQKSDNARQQLERQNKELKAKLQELEGAVKSKFKATISALEAKIGQL 1826
Query: 180 EERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKEDRYEEE-------IKVLSDKL 232
EE+ E + A + ++ LK + Q E + D+Y+E+ +K L +L
Sbjct: 1827 EEQLEQEAKERAAANKLVRRTEKKLKEIFMQVEDERRHADQYKEQMEKANARMKQLKRQL 1886
Query: 233 KEAETRAEFAERSVTKLEKSIDDLEE 258
+EAE A A S KL++ +DD E
Sbjct: 1887 EEAEEEATRANASRRKLQRELDDATE 1912
Score = 68.2 bits (165), Expect = 8e-12
Identities = 56/239 (23%), Positives = 117/239 (48%), Gaps = 26/239 (10%)
Query: 49 LLRVSEDERDRVLEELHKAEDSLLAAEEAAAKAEADVASLNRRIQLVEEELDRAQERLAT 108
LL+V+ E EEL ++ LL +E K E ++ + R+ Q + EE + E+L
Sbjct: 844 LLQVTRQE-----EELQAKDEELLKVKEKQTKVEGELEEMERKHQQLLEEKNILAEQLQA 898
Query: 109 ALQKLEEAEKAA-------DESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRK 161
+ EAE+ E E + +ESR +++EE+ +I + + K+ + +D + +
Sbjct: 899 ETELFAEAEEMRARLAAKKQELEEILHDLESRVEEEEERNQILQNEKKKMQAHIQDLEEQ 958
Query: 162 YEE---VARKL----VIIESDLERAEERAELSEGKCAE-------LEEELKTVTNNLKSL 207
+E +KL V E+ +++ EE L E + ++ +E+ + ++ L
Sbjct: 959 LDEEEGARQKLQLEKVTAEAKIKKMEEEILLLEDQNSKFIKEKKLMEDRIAECSSQLAEE 1018
Query: 208 EAQAEKYSQKEDRYEEEIKVLSDKLKEAETRAEFAERSVTKLEKSIDDLEEKVAHAKEE 266
E +A+ ++ ++ E I L ++LK+ E + E++ KL+ DL++++A + +
Sbjct: 1019 EEKAKNLAKIRNKQEVMISDLEERLKKEEKTRQELEKAKRKLDGETTDLQDQIAELQAQ 1077
Score = 64.3 bits (155), Expect = 1e-10
Identities = 66/310 (21%), Positives = 140/310 (45%), Gaps = 35/310 (11%)
Query: 1 MDAIKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEEDIAAKEKLLRVSEDERDRV 60
++ K ++Q D LD Q ++ E + K+ ++ +A ++ + +ERDR
Sbjct: 1418 LEKTKNRLQQELDDLTVDLDHQRQVASN---LEKKQKKFDQLLAEEKSISARYAEERDRA 1474
Query: 61 LEELHKAED---SLLAAEEAAAKAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAE 117
E + E SL A E A +A+ + N++++ E+L +++ + + +LE+++
Sbjct: 1475 EAEAREKETKALSLARALEEALEAKEEFERQNKQLRADMEDLMSSKDDVGKNVHELEKSK 1534
Query: 118 KAADESERGMKV----IESRAQKDEEKMEIQEIQLKEAK----HIAEDADRKYEEVARKL 169
+A ++ M+ +E Q E+ E+ ++ K + D + EE R L
Sbjct: 1535 RALEQQVEEMRTQLEELEDELQATEDAKLRLEVNMQAMKAQFERDLQTRDEQNEEKKRLL 1594
Query: 170 V--IIESDLERAEERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKEDRYEEEIKV 227
+ + E + E +ER + + ++ + E+ +LK LEAQ E ++ D ++++
Sbjct: 1595 IKQVRELEAELEDERKQRALAVASKKKMEI-----DLKDLEAQIEAANKARDEVIKQLRK 1649
Query: 228 LSDKLKEAETRAEFA--------------ERSVTKLEKSIDDLEEKVAHAKEENLSMHQM 273
L ++K+ + E A E+ + LE I L+E++A ++ Q
Sbjct: 1650 LQAQMKDYQRELEEARASRDEIFAQSKESEKKLKSLEAEILQLQEELASSERARRHAEQE 1709
Query: 274 LDQTLLELNN 283
D+ E+ N
Sbjct: 1710 RDELADEITN 1719
Score = 62.8 bits (151), Expect = 3e-10
Identities = 69/303 (22%), Positives = 135/303 (44%), Gaps = 30/303 (9%)
Query: 2 DAIKKKMQMLKLDK--ENALDRAEQAEADKKAAEDRSKQL---EEDIAAK----EKLLRV 52
+A +K+ + L L + E AL+ E+ E K + L ++D+ EK R
Sbjct: 1477 EAREKETKALSLARALEEALEAKEEFERQNKQLRADMEDLMSSKDDVGKNVHELEKSKRA 1536
Query: 53 SEDERDRVLEELHKAEDSLLAAEEAAAKAEADV----ASLNRRIQLVEEELDRAQERLAT 108
E + + + +L + ED L A E+A + E ++ A R +Q +E+ + + L
Sbjct: 1537 LEQQVEEMRTQLEELEDELQATEDAKLRLEVNMQAMKAQFERDLQTRDEQNEEKKRLLIK 1596
Query: 109 ALQKLEEAEKAADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARK 168
+++L EAE + +R + V + EI LK+ + E A++ +EV ++
Sbjct: 1597 QVREL-EAELEDERKQRALAVASKKK---------MEIDLKDLEAQIEAANKARDEVIKQ 1646
Query: 169 LVIIESDLERAEERAELSEGKCAELEEELKTVTNNLKSLEA-----QAEKYSQKEDR--Y 221
L +++ ++ + E + E+ + K LKSLEA Q E S + R
Sbjct: 1647 LRKLQAQMKDYQRELEEARASRDEIFAQSKESEKKLKSLEAEILQLQEELASSERARRHA 1706
Query: 222 EEEIKVLSDKLKEAETRAEFAERSVTKLEKSIDDLEEKVAHAKEENLSMHQMLDQTLLEL 281
E+E L+D++ + + +LE I LEE++ + ++ +T L++
Sbjct: 1707 EQERDELADEITNSASGKSALLDEKRRLEARIAQLEEELEEEQSNMELLNDRFRKTTLQV 1766
Query: 282 NNM 284
+ +
Sbjct: 1767 DTL 1769
Score = 62.4 bits (150), Expect = 4e-10
Identities = 68/305 (22%), Positives = 139/305 (45%), Gaps = 39/305 (12%)
Query: 4 IKKKMQMLKLDKENALD-RAEQAEADKKAAEDRSKQLEEDIAAKEKLLRVSEDERDRVLE 62
++ MQ +K E L R EQ E K+ + ++LE ++ + K ++ + ++
Sbjct: 1565 LEVNMQAMKAQFERDLQTRDEQNEEKKRLLIKQVRELEAELEDERKQRALAVASKKKMEI 1624
Query: 63 ELHKAEDSLLAAEEAAAKAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADE 122
+L E + EAA KA +V R++Q ++ Q L A +E + E
Sbjct: 1625 DLKDLEAQI----EAANKARDEVIKQLRKLQA---QMKDYQRELEEARASRDEIFAQSKE 1677
Query: 123 SERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAEER 182
SE+ +K +E+ E +++QE +L ++ A+++ +E+A ++ S +
Sbjct: 1678 SEKKLKSLEA------EILQLQE-ELASSERARRHAEQERDELADEITNSASGKSALLDE 1730
Query: 183 AELSEGKCAELEEELKTVTNNLKSL---------------------EAQAEKYSQKEDRY 221
E + A+LEEEL+ +N++ L + A+K +
Sbjct: 1731 KRRLEARIAQLEEELEEEQSNMELLNDRFRKTTLQVDTLNAELAAERSAAQKSDNARQQL 1790
Query: 222 EEEIKVLSDKLKEAE--TRAEFAERSVTKLEKSIDDLEEKVAHAKEENLSMHQMLDQTLL 279
E + K L KL+E E +++F + +++ LE I LEE++ +E + ++++ +T
Sbjct: 1791 ERQNKELKAKLQELEGAVKSKF-KATISALEAKIGQLEEQLEQEAKERAAANKLVRRTEK 1849
Query: 280 ELNNM 284
+L +
Sbjct: 1850 KLKEI 1854
Score = 61.6 bits (148), Expect = 7e-10
Identities = 58/253 (22%), Positives = 109/253 (43%), Gaps = 15/253 (5%)
Query: 23 EQAEADKKAAEDRSKQLEEDIAAKEKLLRVSEDERDRVLEELHKAEDSLL----AAEEAA 78
E +A + AE + + L E++ A + L + D E K E + A EE
Sbjct: 1128 ESEKASRNKAEKQKRDLSEELEALKTELEDTLDTTAAQQELRTKREQEVAELKKALEEET 1187
Query: 79 AKAEADVASLNRR----IQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIESRA 134
EA + + +R ++ + E+L++A+ A + + E E +KV++
Sbjct: 1188 KNHEAQIQDMRQRHATALEELSEQLEQAKRFKANLEKNKQGLETDNKELACEVKVLQQVK 1247
Query: 135 QKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAEERAELSEGK----- 189
+ E K + + Q++E + DR E+A K ++++L+ E +E K
Sbjct: 1248 AESEHKRKKLDAQVQELHAKVSEGDRLRVELAEKASKLQNELDNVSTLLEEAEKKGIKFA 1307
Query: 190 --CAELEEELKTVTNNLKSLEAQAEKYSQKEDRYEEEIKVLSDKLKEAETRAEFAERSVT 247
A LE +L+ L+ Q S + + EEE L ++ +E E + E+ V
Sbjct: 1308 KDAASLESQLQDTQELLQEETRQKLNLSSRIRQLEEEKNSLQEQQEEEEEARKNLEKQVL 1367
Query: 248 KLEKSIDDLEEKV 260
L+ + D ++KV
Sbjct: 1368 ALQSQLADTKKKV 1380
Score = 58.2 bits (139), Expect = 8e-09
Identities = 67/309 (21%), Positives = 134/309 (43%), Gaps = 51/309 (16%)
Query: 4 IKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEEDIAAKEKLLRVSEDERDRVLEE 63
+ +++ L+ +K + ++ E+ E +K E + L+ +A +K + D+ +E
Sbjct: 1334 LSSRIRQLEEEKNSLQEQQEEEEEARKNLEKQVLALQSQLADTKKKV----DDDLGTIES 1389
Query: 64 LHKAEDSLLAAEEAAAKAEADVA----SLNRRIQLVEEELDRA------QERLATALQK- 112
L +A+ LL EA ++ + A L + +++ELD Q ++A+ L+K
Sbjct: 1390 LEEAKKKLLKDAEALSQRLEEKALAYDKLEKTKNRLQQELDDLTVDLDHQRQVASNLEKK 1449
Query: 113 ------------------LEEAEKAADESERGMKVIESRAQKDEEKMEIQEI---QLKEA 151
EE ++A E+ S A+ EE +E +E Q K+
Sbjct: 1450 QKKFDQLLAEEKSISARYAEERDRAEAEAREKETKALSLARALEEALEAKEEFERQNKQL 1509
Query: 152 KHIAEDADRKYEEVARKLVIIESDLERAEERAELSEGKCAELEEELKTVTN-------NL 204
+ ED ++V + + +E E++ E + ELE+EL+ + N+
Sbjct: 1510 RADMEDLMSSKDDVGKNVHELEKSKRALEQQVEEMRTQLEELEDELQATEDAKLRLEVNM 1569
Query: 205 KSLEAQAEKYSQKEDRYEEE--------IKVLSDKLKEAETRAEFAERSVTKLEKSIDDL 256
++++AQ E+ Q D EE ++ L +L++ + A S K+E + DL
Sbjct: 1570 QAMKAQFERDLQTRDEQNEEKKRLLIKQVRELEAELEDERKQRALAVASKKKMEIDLKDL 1629
Query: 257 EEKVAHAKE 265
E ++ A +
Sbjct: 1630 EAQIEAANK 1638
Score = 56.6 bits (135), Expect = 2e-08
Identities = 82/338 (24%), Positives = 153/338 (45%), Gaps = 77/338 (22%)
Query: 5 KKKMQMLKLDKENALDRAEQA----EADKKAAEDRSKQLEEDIAAKEKLLRVSEDERDRV 60
KKKMQ D E LD E A + +K AE + K++EE+I + ED+ +
Sbjct: 945 KKKMQAHIQDLEEQLDEEEGARQKLQLEKVTAEAKIKKMEEEIL-------LLEDQNSKF 997
Query: 61 LEELHKAED------SLLAAEEAAAKAEADVASLNRRIQLVEEELDRAQERLATALQKLE 114
++E ED S LA EE AK ++A + + +++ +L+ ++ Q+LE
Sbjct: 998 IKEKKLMEDRIAECSSQLAEEEEKAK---NLAKIRNKQEVMISDLEERLKKEEKTRQELE 1054
Query: 115 EAEKAADESERGMK--VIESRAQKDEEKME----------------------------IQ 144
+A++ D ++ + E +AQ DE K++ ++
Sbjct: 1055 KAKRKLDGETTDLQDQIAELQAQIDELKLQLAKKEEELQGALARGDDETLHKNNALKVVR 1114
Query: 145 EIQLKEAKHIAED----------ADRKYEEVARKLVIIESDLERA-------EERAELSE 187
E+Q + A+ + ED A+++ +++ +L ++++LE +E E
Sbjct: 1115 ELQAQIAE-LQEDFESEKASRNKAEKQKRDLSEELEALKTELEDTLDTTAAQQELRTKRE 1173
Query: 188 GKCAELEEELKTVTNNLKSLEAQAEKYSQKEDRYEEEIKVLSDKLKEAETRAEFAERSVT 247
+ AEL++ L+ T K+ EAQ + Q R+ ++ LS++L++A+ E++
Sbjct: 1174 QEVAELKKALEEET---KNHEAQIQDMRQ---RHATALEELSEQLEQAKRFKANLEKNKQ 1227
Query: 248 KLEKSIDDL--EEKV-AHAKEENLSMHQMLDQTLLELN 282
LE +L E KV K E+ + LD + EL+
Sbjct: 1228 GLETDNKELACEVKVLQQVKAESEHKRKKLDAQVQELH 1265
Score = 56.6 bits (135), Expect = 2e-08
Identities = 55/288 (19%), Positives = 125/288 (43%), Gaps = 24/288 (8%)
Query: 4 IKKKMQMLKLDKENALD----------RAEQAEAD-KKAAEDRSKQLEEDIAAKEKLLRV 52
+ ++++ LK + E+ LD + EQ A+ KKA E+ +K E I +
Sbjct: 1144 LSEELEALKTELEDTLDTTAAQQELRTKREQEVAELKKALEEETKNHEAQIQDMRQRHAT 1203
Query: 53 SEDERDRVLEELHKAEDSLLAAEEAAAKAEADVASLNRRIQLVEEELDRAQERLATALQK 112
+ +E LE+ + + +L ++ ++A + +Q V+ E + +++L +Q+
Sbjct: 1204 ALEELSEQLEQAKRFKANLEKNKQGLETDNKELACEVKVLQQVKAESEHKRKKLDAQVQE 1263
Query: 113 LEEAEKAADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVII 172
L D R + E+ ++Q +L + E+A++K + A+ +
Sbjct: 1264 LHAKVSEGDRL---------RVELAEKASKLQN-ELDNVSTLLEEAEKKGIKFAKDAASL 1313
Query: 173 ESDLERAEERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKEDRYEEEIKVLSDKL 232
ES L+ +E + + L ++ + SL+ Q E+ + E+++ L +L
Sbjct: 1314 ESQLQDTQELLQEETRQKLNLSSRIRQLEEEKNSLQEQQEEEEEARKNLEKQVLALQSQL 1373
Query: 233 KEAETRAEFAERSVTKLEKSIDDL---EEKVAHAKEENLSMHQMLDQT 277
+ + + + ++ LE++ L E ++ EE + L++T
Sbjct: 1374 ADTKKKVDDDLGTIESLEEAKKKLLKDAEALSQRLEEKALAYDKLEKT 1421
Score = 55.1 bits (131), Expect = 7e-08
Identities = 64/271 (23%), Positives = 127/271 (46%), Gaps = 20/271 (7%)
Query: 6 KKMQMLKLDKENALDRAEQAEADKKAAE--DRSKQLEEDIAAKEKLLRVSEDERDRV--- 60
K ++LK+ ++ E E ++K + + L E + A+ +L +E+ R R+
Sbjct: 857 KDEELLKVKEKQTKVEGELEEMERKHQQLLEEKNILAEQLQAETELFAEAEEMRARLAAK 916
Query: 61 ---LEE-LHKAEDSLLAAEEAAAKAEADVASLNRRIQLVEEELDRAQ-ERLATALQKLEE 115
LEE LH E + EE + + + IQ +EE+LD + R L+K+
Sbjct: 917 KQELEEILHDLESRVEEEEERNQILQNEKKKMQAHIQDLEEQLDEEEGARQKLQLEKV-T 975
Query: 116 AEKAADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVAR---KLVII 172
AE + E + ++E + K ++ ++ E ++ E + + K + +A+ K ++
Sbjct: 976 AEAKIKKMEEEILLLEDQNSKFIKEKKLMEDRIAECSSQLAEEEEKAKNLAKIRNKQEVM 1035
Query: 173 ESDLE---RAEE--RAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKEDRYEEEIKV 227
SDLE + EE R EL + K +L+ E + + + L+AQ ++ + + EEE++
Sbjct: 1036 ISDLEERLKKEEKTRQELEKAK-RKLDGETTDLQDQIAELQAQIDELKLQLAKKEEELQG 1094
Query: 228 LSDKLKEAETRAEFAERSVTKLEKSIDDLEE 258
+ + A + V +L+ I +L+E
Sbjct: 1095 ALARGDDETLHKNNALKVVRELQAQIAELQE 1125
Score = 55.1 bits (131), Expect = 7e-08
Identities = 63/264 (23%), Positives = 122/264 (46%), Gaps = 27/264 (10%)
Query: 12 KLDKENALDRAEQAEADKKAAE--DRSKQLEEDIAAKEKLLRVSEDERDRVLEELHKAED 69
KLD + A+ +E D+ E +++ +L+ ++ LL +E + + ++ E
Sbjct: 1256 KLDAQVQELHAKVSEGDRLRVELAEKASKLQNELDNVSTLLEEAEKKGIKFAKDAASLES 1315
Query: 70 SLLAAEEAAAKAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKV 129
L +E + +L+ RI+ +EEE + QE + EE E+A E+ +
Sbjct: 1316 QLQDTQELLQEETRQKLNLSSRIRQLEEEKNSLQE-------QQEEEEEARKNLEKQVLA 1368
Query: 130 IESRAQKDEEKM--EIQEIQ-LKEA-KHIAEDADRKYEEVARKLVIIESDLERAEERAEL 185
++S+ ++K+ ++ I+ L+EA K + +DA+ + + K + + LE+ + R
Sbjct: 1369 LQSQLADTKKKVDDDLGTIESLEEAKKKLLKDAEALSQRLEEKALAYDK-LEKTKNR--- 1424
Query: 186 SEGKCAELEEELKTVTNNL---KSLEAQAEKYSQKEDRYEEEIKVLSDKLKEAETRAEFA 242
L++EL +T +L + + + EK +K D+ E K +S + E RAE
Sbjct: 1425 -------LQQELDDLTVDLDHQRQVASNLEKKQKKFDQLLAEEKSISARYAEERDRAEAE 1477
Query: 243 ERSVTKLEKSIDDLEEKVAHAKEE 266
R S+ E+ AKEE
Sbjct: 1478 AREKETKALSLARALEEALEAKEE 1501
Score = 48.5 bits (114), Expect = 7e-06
Identities = 51/230 (22%), Positives = 105/230 (45%), Gaps = 20/230 (8%)
Query: 20 DRAEQAEADKKAAEDRSKQ-------LEEDIAAKEKLLRVSEDERDRVLEELHKAEDSLL 72
+ E+ +++ + DR ++ L ++AA+ + S++ R + LE +K + L
Sbjct: 1743 EELEEEQSNMELLNDRFRKTTLQVDTLNAELAAERSAAQKSDNARQQ-LERQNKELKAKL 1801
Query: 73 AAEEAAAKAE--ADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVI 130
E A K++ A +++L +I +EE+L++ + A A + + EK E ++
Sbjct: 1802 QELEGAVKSKFKATISALEAKIGQLEEQLEQEAKERAAANKLVRRTEKKLKEIFMQVEDE 1861
Query: 131 ESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAEERAELSEGKC 190
A + +E+ME ++K+ K E+A+ EE R ++ E +EG
Sbjct: 1862 RRHADQYKEQMEKANARMKQLKRQLEEAE---EEATRANASRRKLQRELDDATEANEG-- 1916
Query: 191 AELEEELKTVTNNLK---SLEAQAEKYSQKEDRYEEEIKVLSDKLKEAET 237
L E+ T+ N L+ + + + +++ E LSD E++T
Sbjct: 1917 --LSREVSTLKNRLRRGGPISFSSSRSGRRQLHLEGASLELSDDDTESKT 1964
Score = 45.8 bits (107), Expect = 4e-05
Identities = 33/144 (22%), Positives = 73/144 (50%), Gaps = 8/144 (5%)
Query: 131 ESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAEE---RAELSE 187
E KDEE ++++E Q K + E+ +RK++++ + I+ L+ E AE
Sbjct: 852 EELQAKDEELLKVKEKQTKVEGEL-EEMERKHQQLLEEKNILAEQLQAETELFAEAEEMR 910
Query: 188 GKCAELEEELKTVTNNLKSLEAQAEKYSQ----KEDRYEEEIKVLSDKLKEAETRAEFAE 243
+ A ++EL+ + ++L+S + E+ +Q ++ + + I+ L ++L E E + +
Sbjct: 911 ARLAAKKQELEEILHDLESRVEEEEERNQILQNEKKKMQAHIQDLEEQLDEEEGARQKLQ 970
Query: 244 RSVTKLEKSIDDLEEKVAHAKEEN 267
E I +EE++ +++N
Sbjct: 971 LEKVTAEAKIKKMEEEILLLEDQN 994
Score = 39.3 bits (90), Expect = 0.004
Identities = 33/145 (22%), Positives = 63/145 (43%), Gaps = 16/145 (11%)
Query: 136 KDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAEERAELSEGKCAELEE 195
+ EE+++ ++ +L + K + + EE+ RK +L E K L E
Sbjct: 849 RQEEELQAKDEELLKVKEKQTKVEGELEEMERK-------------HQQLLEEKNI-LAE 894
Query: 196 ELKTVTNNLKSLEAQAEKYSQKEDRYEEEIKVLSDKLKEAETRAEFAERSVTKLEKSIDD 255
+L+ T E + + K+ EE + L +++E E R + + K++ I D
Sbjct: 895 QLQAETELFAEAEEMRARLAAKKQELEEILHDLESRVEEEEERNQILQNEKKKMQAHIQD 954
Query: 256 LEEKVAHAKEENLSMHQMLDQTLLE 280
LEE++ +EE L++ E
Sbjct: 955 LEEQL--DEEEGARQKLQLEKVTAE 977
Score = 28.5 bits (62), Expect = 7.0
Identities = 22/89 (24%), Positives = 41/89 (46%), Gaps = 7/89 (7%)
Query: 5 KKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEEDIAAKEKLLRVSEDERDRVLEEL 64
+KK++ + + E+ A+Q + + A R KQL ++ L +E+E R
Sbjct: 1848 EKKLKEIFMQVEDERRHADQYKEQMEKANARMKQL-------KRQLEEAEEEATRANASR 1900
Query: 65 HKAEDSLLAAEEAAAKAEADVASLNRRIQ 93
K + L A EA +V++L R++
Sbjct: 1901 RKLQRELDDATEANEGLSREVSTLKNRLR 1929
>gi|145312241 differentially expressed in FDCP 6 homolog [Homo
sapiens]
Length = 631
Score = 79.0 bits (193), Expect = 5e-15
Identities = 64/251 (25%), Positives = 127/251 (50%), Gaps = 29/251 (11%)
Query: 5 KKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEEDIAAKEKLLRVSEDERDRVLEEL 64
+++ + + KE L R +Q + +K+ + L+E E+LL+ E+ R EL
Sbjct: 333 REQRERRRAAKEEELLRLQQLQEEKERKLQELELLQEAQRQAERLLQEEEERRRSQHREL 392
Query: 65 HKA-EDSLLAAEEAAAKAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADES 123
+A E L AE+A A +A++ +L EEE R ++R+ ++LEE ++ E+
Sbjct: 393 QQALEGQLREAEQARASMQAEM-------ELKEEEAARQRQRI----KELEEMQQRLQEA 441
Query: 124 ERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAEERA 183
+ +E +A++DEE + I + +L E + EE ++L+ ++ + ER ERA
Sbjct: 442 LQ----LEVKARRDEESVRIAQTRLLEEE----------EEKLKQLMQLKEEQERYIERA 487
Query: 184 ELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKEDRYEEEIKVLSDKLKEAETRAEFAE 243
+ + EL++E+ + +L+ + Q E+ Q R +E+++ KL++A T +
Sbjct: 488 QQEK---EELQQEMAQQSRSLQQAQQQLEEVRQNRQRADEDVEAAQRKLRQASTNVKHWN 544
Query: 244 RSVTKLEKSID 254
+ +L I+
Sbjct: 545 VQMNRLMHPIE 555
Score = 46.2 bits (108), Expect = 3e-05
Identities = 44/220 (20%), Positives = 96/220 (43%), Gaps = 26/220 (11%)
Query: 73 AAEEAAAKAEAD-VASLNRRI-QLVEEELDRAQERLATALQKLEEAEKAADESERGMKVI 130
AA + A + +A+ SL++ + Q E+ ++ + R A ++L ++ +E ER ++ +
Sbjct: 305 AAIQMAIRLQAEGKTSLHKDLKQKRREQREQRERRRAAKEEELLRLQQLQEEKERKLQEL 364
Query: 131 ESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAEERAELSEGKC 190
E +QE Q + + + E+ +R+ + +E L AE+ + +
Sbjct: 365 EL----------LQEAQRQAERLLQEEEERRRSQHRELQQALEGQLREAEQARASMQAEM 414
Query: 191 AELEEELKTVTNNLKSLEAQAEKYSQ------KEDRYEEEIKVL--------SDKLKEAE 236
EEE +K LE ++ + K R EE +++ +KLK+
Sbjct: 415 ELKEEEAARQRQRIKELEEMQQRLQEALQLEVKARRDEESVRIAQTRLLEEEEEKLKQLM 474
Query: 237 TRAEFAERSVTKLEKSIDDLEEKVAHAKEENLSMHQMLDQ 276
E ER + + ++ ++L++++A Q L++
Sbjct: 475 QLKEEQERYIERAQQEKEELQQEMAQQSRSLQQAQQQLEE 514
>gi|30581135 structural maintenance of chromosomes 1A [Homo sapiens]
Length = 1233
Score = 78.2 bits (191), Expect = 8e-15
Identities = 60/266 (22%), Positives = 134/266 (50%), Gaps = 17/266 (6%)
Query: 7 KMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEEDIAAKEKLLRVSEDERDRVLEELHK 66
++++ KL+KE A + ++ E DKK R ++E+++ K+K L E+ ++ +E+ +
Sbjct: 232 EVEIEKLNKELA-SKNKEIEKDKK----RMDKVEDELKEKKKELGKMMREQQQIEKEIKE 286
Query: 67 AEDSLLAAEEAAAKAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERG 126
+ L KA+ + + ++++ ++ L AQ+ ++E EK E+
Sbjct: 287 KDSELNQKRPQYIKAKENTSHKIKKLEAAKKSLQNAQKHYKKRKGDMDELEKEMLSVEKA 346
Query: 127 MKVIESRAQKDEEK----MEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAEER 182
+ E R +++ + + ++E Q+K+ + E+A ++ +A++L D + ++R
Sbjct: 347 RQEFEERMEEESQSQGRDLTLEENQVKKYHRLKEEASKRAATLAQELEKFNRDQKADQDR 406
Query: 183 AELSEGKCAELE----EELKTVTNNLKSLEAQAEKYSQKEDRYEEEIKVLSDKLKEAETR 238
+L E K E E ++L+ + N K +E + E+Y + EE K L +L E
Sbjct: 407 LDLEERKKVETEAKIKQKLREIEENQKRIE-KLEEYITTSKQSLEEQKKLEGELTE---E 462
Query: 239 AEFAERSVTKLEKSIDDLEEKVAHAK 264
E A+R + ++ K ++ + E++ A+
Sbjct: 463 VEMAKRRIDEINKELNQVMEQLGDAR 488
Score = 54.7 bits (130), Expect = 9e-08
Identities = 72/286 (25%), Positives = 129/286 (45%), Gaps = 23/286 (8%)
Query: 12 KLDKENALDRAEQAEADKKAAEDRS-KQLEEDIAAKEKLLRVSE--DERDRVLEELHKAE 68
+L+K L +A + A E + K +E A E++ R E E D+ +E+ KAE
Sbjct: 120 ELEKLGILIKARNFLVFQGAVESIAMKNPKERTALFEEISRSGELAQEYDKRKKEMVKAE 179
Query: 69 DSL---------LAAEEAAAKAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKA 119
+ +AAE AK E + A R Q +++E+ RAQ +L L KL E
Sbjct: 180 EDTQFNYHRKKNIAAERKEAKQEKEEAD---RYQRLKDEVVRAQVQLQ--LFKLYHNEVE 234
Query: 120 ADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERA 179
++ + + +KD+++M+ E +LKE K R+ +++ ++ I E D E
Sbjct: 235 IEKLNKELASKNKEIEKDKKRMDKVEDELKEKKKELGKMMREQQQIEKE--IKEKDSELN 292
Query: 180 EERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKE---DRYEEEIKVLSDKLKEAE 236
++R + + K ++K + KSL+ + Y +++ D E+E+ + +E E
Sbjct: 293 QKRPQYIKAK-ENTSHKIKKLEAAKKSLQNAQKHYKKRKGDMDELEKEMLSVEKARQEFE 351
Query: 237 TRAEFAERSVTKLEKSIDDLEEKVAHAKEENLSMHQMLDQTLLELN 282
R E +S + ++ +K KEE L Q L + N
Sbjct: 352 ERMEEESQSQGRDLTLEENQVKKYHRLKEEASKRAATLAQELEKFN 397
Score = 40.8 bits (94), Expect = 0.001
Identities = 57/255 (22%), Positives = 110/255 (43%), Gaps = 38/255 (14%)
Query: 31 AAEDRSKQLEEDIAAKEKLLRVSEDERDRVLEELHKAEDSLLAAEEAAAKAEADVASLNR 90
A++ ++K D A +KL +++++R+ EEL K + E + ++ L
Sbjct: 656 ASDLKAKARRWDEKAVDKL----KEKKERLTEEL-KEQMKAKRKEAELRQVQSQAHGLQM 710
Query: 91 RIQLVEEELDRAQER-LATALQKLEEAEKAADESERGMKVIESRAQKDEEKMEIQEIQLK 149
R++ + +L++ + R LA LQ+ + E + I+ Q E +M+ LK
Sbjct: 711 RLKYSQSDLEQTKTRHLALNLQEKSKLESELANFGPRINDIKRIIQSREREMK----DLK 766
Query: 150 EAKHIAEDADRKYEEVARKLVIIESDLERAEERAELSEGKCAELEEELKTVTNNLKSLEA 209
E + ED +EE R E+ E EEE N +
Sbjct: 767 EKMNQVED--EVFEEFCR----------------EIGVRNIREFEEEKVKRQNEIAKKRL 808
Query: 210 QAEKYSQKEDRYEEEIKVLSDKLKEAETRAEFAERSVTKLEKSIDDLEEKVAHAKEENLS 269
+ E ++ R ++ ++LKE + + E++V K E I+ L+ KEE
Sbjct: 809 EFEN---QKTRLGIQLDFEKNQLKEDQDKVHMWEQTVKKDENEIEKLK------KEEQRH 859
Query: 270 MHQMLDQTLLELNNM 284
M +++D+T+ +L ++
Sbjct: 860 M-KIIDETMAQLQDL 873
Score = 40.4 bits (93), Expect = 0.002
Identities = 31/124 (25%), Positives = 62/124 (50%), Gaps = 14/124 (11%)
Query: 15 KENALDRA-------EQAEADKKAAEDR-----SKQLEEDIAAKEKLLRVSEDER--DRV 60
KE A RA E+ D+KA +DR K++E + K+KL + E+++ +++
Sbjct: 379 KEEASKRAATLAQELEKFNRDQKADQDRLDLEERKKVETEAKIKQKLREIEENQKRIEKL 438
Query: 61 LEELHKAEDSLLAAEEAAAKAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAA 120
E + ++ SL ++ + +V RRI + +EL++ E+L A +E+ +
Sbjct: 439 EEYITTSKQSLEEQKKLEGELTEEVEMAKRRIDEINKELNQVMEQLGDARIDRQESSRQQ 498
Query: 121 DESE 124
++E
Sbjct: 499 RKAE 502
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.303 0.121 0.290
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 8,455,194
Number of Sequences: 37866
Number of extensions: 390376
Number of successful extensions: 14725
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 751
Number of HSP's successfully gapped in prelim test: 1012
Number of HSP's that attempted gapping in prelim test: 3192
Number of HSP's gapped (non-prelim): 6151
length of query: 284
length of database: 18,247,518
effective HSP length: 101
effective length of query: 183
effective length of database: 14,423,052
effective search space: 2639418516
effective search space used: 2639418516
T: 11
A: 40
X1: 17 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 43 (21.8 bits)
S2: 61 (28.1 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.