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Search of human proteins with 62955042
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|62955042 PAR-6 beta [Homo sapiens]
(372 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|62955042 PAR-6 beta [Homo sapiens] 739 0.0
gi|14210518 PAR-6 gamma protein [Homo sapiens] 394 e-110
gi|8394417 par-6 partitioning defective 6 homolog alpha isoform ... 328 5e-90
gi|82659097 par-6 partitioning defective 6 homolog alpha isoform... 324 9e-89
gi|38570142 membrane protein, palmitoylated 5 [Homo sapiens] 57 2e-08
gi|21536464 palmitoylated membrane protein 3 [Homo sapiens] 55 8e-08
gi|186972120 calcium/calmodulin-dependent serine protein kinase ... 52 7e-07
gi|110346438 FERM and PDZ domain containing 2 isoform 1 [Homo sa... 50 2e-06
gi|110346436 FERM and PDZ domain containing 2 isoform 3 [Homo sa... 50 2e-06
gi|14780902 membrane protein, palmitoylated 4 [Homo sapiens] 49 6e-06
gi|8922944 lin-7 homolog C [Homo sapiens] 49 9e-06
gi|186700629 calcium/calmodulin-dependent serine protein kinase ... 48 2e-05
gi|186700627 calcium/calmodulin-dependent serine protein kinase ... 48 2e-05
gi|4759306 lin-7 homolog A [Homo sapiens] 48 2e-05
gi|45827729 scribble isoform b [Homo sapiens] 48 2e-05
gi|45827731 scribble isoform a [Homo sapiens] 48 2e-05
gi|218156340 chapsyn-110 isoform 3 [Homo sapiens] 47 2e-05
gi|218156338 chapsyn-110 isoform 1 [Homo sapiens] 47 2e-05
gi|91199538 chapsyn-110 isoform 2 [Homo sapiens] 47 2e-05
gi|11545920 lin-7 homolog B [Homo sapiens] 47 2e-05
gi|148746189 multiple PDZ domain protein [Homo sapiens] 47 4e-05
gi|119943106 synapse-associated protein 102 isoform a [Homo sapi... 46 5e-05
gi|4505237 palmitoylated membrane protein 1 [Homo sapiens] 46 5e-05
gi|31742501 sorting nexin family member 27 [Homo sapiens] 46 5e-05
gi|87196343 PDZ domain containing 2 [Homo sapiens] 46 5e-05
gi|218505835 membrane-associated guanylate kinase-related 3 iso... 46 5e-05
gi|155969695 membrane-associated guanylate kinase-related 3 iso... 46 5e-05
gi|140561024 CASK-interacting protein CIP98 isoform 1 [Homo sapi... 46 6e-05
gi|24025688 ligand of numb-protein X 2 [Homo sapiens] 45 8e-05
gi|111154074 palmitoylated membrane protein 7 [Homo sapiens] 45 1e-04
>gi|62955042 PAR-6 beta [Homo sapiens]
Length = 372
Score = 739 bits (1907), Expect = 0.0
Identities = 372/372 (100%), Positives = 372/372 (100%)
Query: 1 MNRSHRHGAGSGCLGTMEVKSKFGAEFRRFSLERSKPGKFEEFYGLLQHVHKIPNVDVLV 60
MNRSHRHGAGSGCLGTMEVKSKFGAEFRRFSLERSKPGKFEEFYGLLQHVHKIPNVDVLV
Sbjct: 1 MNRSHRHGAGSGCLGTMEVKSKFGAEFRRFSLERSKPGKFEEFYGLLQHVHKIPNVDVLV 60
Query: 61 GYADIHGDLLPINNDDNYHKAVSTANPLLRIFIQKKEEADYSAFGTDTLIKKKNVLTNVL 120
GYADIHGDLLPINNDDNYHKAVSTANPLLRIFIQKKEEADYSAFGTDTLIKKKNVLTNVL
Sbjct: 61 GYADIHGDLLPINNDDNYHKAVSTANPLLRIFIQKKEEADYSAFGTDTLIKKKNVLTNVL 120
Query: 121 RPDNHRKKPHIVISMPQDFRPVSSIIDVDILPETHRRVRLYKYGTEKPLGFYIRDGSSVR 180
RPDNHRKKPHIVISMPQDFRPVSSIIDVDILPETHRRVRLYKYGTEKPLGFYIRDGSSVR
Sbjct: 121 RPDNHRKKPHIVISMPQDFRPVSSIIDVDILPETHRRVRLYKYGTEKPLGFYIRDGSSVR 180
Query: 181 VTPHGLEKVPGIFISRLVPGGLAQSTGLLAVNDEVLEVNGIEVSGKSLDQVTDMMIANSR 240
VTPHGLEKVPGIFISRLVPGGLAQSTGLLAVNDEVLEVNGIEVSGKSLDQVTDMMIANSR
Sbjct: 181 VTPHGLEKVPGIFISRLVPGGLAQSTGLLAVNDEVLEVNGIEVSGKSLDQVTDMMIANSR 240
Query: 241 NLIITVRPANQRNNVVRNSRTSGSSGQSTDNSLLGYPQQIEPSFEPEDEDSEEDDIIIED 300
NLIITVRPANQRNNVVRNSRTSGSSGQSTDNSLLGYPQQIEPSFEPEDEDSEEDDIIIED
Sbjct: 241 NLIITVRPANQRNNVVRNSRTSGSSGQSTDNSLLGYPQQIEPSFEPEDEDSEEDDIIIED 300
Query: 301 NGVPQQIPKAVPNTESLESLTQIELSFESGQNGFIPSNEVSLAAIASSSNTEFETHAPDQ 360
NGVPQQIPKAVPNTESLESLTQIELSFESGQNGFIPSNEVSLAAIASSSNTEFETHAPDQ
Sbjct: 301 NGVPQQIPKAVPNTESLESLTQIELSFESGQNGFIPSNEVSLAAIASSSNTEFETHAPDQ 360
Query: 361 KLLEEDGTIITL 372
KLLEEDGTIITL
Sbjct: 361 KLLEEDGTIITL 372
>gi|14210518 PAR-6 gamma protein [Homo sapiens]
Length = 376
Score = 394 bits (1013), Expect = e-110
Identities = 197/297 (66%), Positives = 245/297 (82%), Gaps = 5/297 (1%)
Query: 17 MEVKSKFGAEFRRFSLERSKPGKFEEFYGLLQHVHKIPNVDVLVGYADIHGDLLPINNDD 76
+EVKSKFGAEFRRFSL+R KPGKFE+FY L+ H H I N DV +GYAD+HGDLLPINNDD
Sbjct: 19 VEVKSKFGAEFRRFSLDRHKPGKFEDFYKLVVHTHHISNSDVTIGYADVHGDLLPINNDD 78
Query: 77 NYHKAVSTANPLLRIFIQKKEEADYSAFGTDTLIKKKNVLTNVLRPDNHRKKPHIVISMP 136
N+ KAVS+ANPLLR+FIQK+EEA+ + G +L +++ L LR + R++ H+ I +P
Sbjct: 79 NFCKAVSSANPLLRVFIQKREEAERGSLGAGSLCRRRRAL-GALRDEGPRRRAHLDIGLP 137
Query: 137 QDFRPVSSIIDVDILPETHRRVRLYKYGTEKPLGFYIRDGSSVRVTPHGLEKVPGIFISR 196
+DFRPVSSIIDVD++PETHRRVRL+++G EKPLGFYIRDG+SVRVTPHGLEKVPGIFISR
Sbjct: 138 RDFRPVSSIIDVDLVPETHRRVRLHRHGCEKPLGFYIRDGASVRVTPHGLEKVPGIFISR 197
Query: 197 LVPGGLAQSTGLLAVNDEVLEVNGIEVSGKSLDQVTDMMIANSRNLIITVRPANQRNNVV 256
+VPGGLA+STGLLAVNDEVLEVNGIEV+GK+LDQVTDMMIANS NLI+TV+PANQRNNVV
Sbjct: 198 MVPGGLAESTGLLAVNDEVLEVNGIEVAGKTLDQVTDMMIANSHNLIVTVKPANQRNNVV 257
Query: 257 RNSRTSGSSGQSTDNS--LLGYPQ-QIEPSFEPEDEDSEED-DIIIEDNGVPQQIPK 309
R R GSSG +D + +G P ++ +F P++ +S+ED D++IE P + P+
Sbjct: 258 RGGRALGSSGPPSDGTAGFVGPPAPRVLQNFHPDEAESDEDNDVVIEGTLEPARPPQ 314
>gi|8394417 par-6 partitioning defective 6 homolog alpha isoform 1
[Homo sapiens]
Length = 346
Score = 328 bits (841), Expect = 5e-90
Identities = 175/291 (60%), Positives = 224/291 (76%), Gaps = 16/291 (5%)
Query: 17 MEVKSKFGAEFRRFSLERSKPGKFEEFYGLLQHVHKIPNVDVLVGYADIHGDLLPINNDD 76
+EVKSKF AEFRRF+L R+ F+EF LL+ VH+IP +DVL+GY D HGDLLP+ NDD
Sbjct: 16 VEVKSKFDAEFRRFALPRASVSGFQEFSRLLRAVHQIPGLDVLLGYTDAHGDLLPLTNDD 75
Query: 77 NYHKAVSTANPLLRIFIQKKEEADYS--AFGTDTLIKKKNVLTNVLRPDNH-RKKPHIVI 133
+ H+A+++ P LR+ +QK+ EAD S AF +++L ++K L +LRP R +P ++I
Sbjct: 76 SLHRALASGPPPLRLLVQKRAEADSSGLAFASNSLQRRKKGL--LLRPVAPLRTRPPLLI 133
Query: 134 SMPQDFRPVSSIIDVDILPETHRRVRLYKYGTEKPLGFYIRDGSSVRVTPHGLEKVPGIF 193
S+PQDFR VSS+IDVD+LPETHRRVRL+K+G+++PLGFYIRDG SVRV P GLE+VPGIF
Sbjct: 134 SLPQDFRQVSSVIDVDLLPETHRRVRLHKHGSDRPLGFYIRDGMSVRVAPQGLERVPGIF 193
Query: 194 ISRLVPGGLAQSTGLLAVNDEVLEVNGIEVSGKSLDQVTDMMIANSRNLIITVRPANQRN 253
ISRLV GGLA+STGLLAV+DE+LEVNGIEV+GK+LDQVTDMM+ANS NLI+TV+PANQRN
Sbjct: 194 ISRLVRGGLAESTGLLAVSDEILEVNGIEVAGKTLDQVTDMMVANSHNLIVTVKPANQRN 253
Query: 254 NVVRNSRTSGSSGQSTDNSLLGYPQQIEPSFEPEDEDSEEDDIIIEDNGVP 304
NVVR G+SG+ T G P EP D D + D++IE+ P
Sbjct: 254 NVVR-----GASGRLTGPPSAG-PGPAEP-----DSDDDSSDLVIENRQPP 293
>gi|82659097 par-6 partitioning defective 6 homolog alpha isoform 2
[Homo sapiens]
Length = 345
Score = 324 bits (830), Expect = 9e-89
Identities = 175/291 (60%), Positives = 224/291 (76%), Gaps = 17/291 (5%)
Query: 17 MEVKSKFGAEFRRFSLERSKPGKFEEFYGLLQHVHKIPNVDVLVGYADIHGDLLPINNDD 76
+EVKSKF AEFRRF+L R+ F+EF LL+ VH+IP +DVL+GY D HGDLLP+ NDD
Sbjct: 16 VEVKSKFDAEFRRFALPRASVSGFQEFSRLLRAVHQIPGLDVLLGYTDAHGDLLPLTNDD 75
Query: 77 NYHKAVSTANPLLRIFIQKKEEADYS--AFGTDTLIKKKNVLTNVLRPDNH-RKKPHIVI 133
+ H+A+++ P LR+ +QK+E AD S AF +++L ++K L +LRP R +P ++I
Sbjct: 76 SLHRALASGPPPLRLLVQKRE-ADSSGLAFASNSLQRRKKGL--LLRPVAPLRTRPPLLI 132
Query: 134 SMPQDFRPVSSIIDVDILPETHRRVRLYKYGTEKPLGFYIRDGSSVRVTPHGLEKVPGIF 193
S+PQDFR VSS+IDVD+LPETHRRVRL+K+G+++PLGFYIRDG SVRV P GLE+VPGIF
Sbjct: 133 SLPQDFRQVSSVIDVDLLPETHRRVRLHKHGSDRPLGFYIRDGMSVRVAPQGLERVPGIF 192
Query: 194 ISRLVPGGLAQSTGLLAVNDEVLEVNGIEVSGKSLDQVTDMMIANSRNLIITVRPANQRN 253
ISRLV GGLA+STGLLAV+DE+LEVNGIEV+GK+LDQVTDMM+ANS NLI+TV+PANQRN
Sbjct: 193 ISRLVRGGLAESTGLLAVSDEILEVNGIEVAGKTLDQVTDMMVANSHNLIVTVKPANQRN 252
Query: 254 NVVRNSRTSGSSGQSTDNSLLGYPQQIEPSFEPEDEDSEEDDIIIEDNGVP 304
NVVR G+SG+ T G P EP D D + D++IE+ P
Sbjct: 253 NVVR-----GASGRLTGPPSAG-PGPAEP-----DSDDDSSDLVIENRQPP 292
>gi|38570142 membrane protein, palmitoylated 5 [Homo sapiens]
Length = 675
Score = 57.4 bits (137), Expect = 2e-08
Identities = 35/99 (35%), Positives = 55/99 (55%), Gaps = 13/99 (13%)
Query: 153 ETHRRVRLYKYGTEKPLGFYIRDGSSVRVTPHGLEKVPGIFISRLVPGGLAQSTGLLAVN 212
ET + VR+ K + PLG +R+ ++ + ISR+V GG A+ +GLL
Sbjct: 252 ETVKIVRIEK-ARDIPLGATVRN------------EMDSVIISRIVKGGAAEKSGLLHEG 298
Query: 213 DEVLEVNGIEVSGKSLDQVTDMMIANSRNLIITVRPANQ 251
DEVLE+NGIE+ GK +++V D++ L + P+ Q
Sbjct: 299 DEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFVLIPSQQ 337
>gi|21536464 palmitoylated membrane protein 3 [Homo sapiens]
Length = 585
Score = 55.5 bits (132), Expect = 8e-08
Identities = 36/120 (30%), Positives = 63/120 (52%), Gaps = 12/120 (10%)
Query: 141 PVSSIIDVDILPETHRRVRLYKYGTEKPLGFYIRDGSSVRVTPHGLEKVPGIFISRLVPG 200
P+ ID D E+ + VRL K ++PLG IR E + ++R++ G
Sbjct: 121 PLPDNIDEDFDEESVKIVRLVK--NKEPLGATIRRD----------EHSGAVVVARIMRG 168
Query: 201 GLAQSTGLLAVNDEVLEVNGIEVSGKSLDQVTDMMIANSRNLIITVRPANQRNNVVRNSR 260
G A +GL+ V DE+ EVNGI V K D+++ ++ + ++ + + PA Q + ++ S+
Sbjct: 169 GAADRSGLVHVGDELREVNGIAVLHKRPDEISQILAQSQGSITLKIIPATQEEDRLKESK 228
>gi|186972120 calcium/calmodulin-dependent serine protein kinase
isoform 1 [Homo sapiens]
Length = 921
Score = 52.4 bits (124), Expect = 7e-07
Identities = 37/149 (24%), Positives = 77/149 (51%), Gaps = 18/149 (12%)
Query: 141 PVSSIIDVDILPETHRRVRLYKYGTEKPLGFYIRDGSSVRVTPHGLEKVPGIFISRLVPG 200
P S+ D+D+ T R+ ++ T++P+G ++ + ++ ++R++ G
Sbjct: 473 PESANGDMDMENVTRVRLVQFQKNTDEPMGITLK-----------MNELNHCIVARIMHG 521
Query: 201 GLAQSTGLLAVNDEVLEVNGIEVSGKSLDQVTDMMIANSRNLIITVRPA--NQRNNVVRN 258
G+ G L V DE+ E+NGI V+ ++++Q+ M+ ++ + P+ Q ++ R+
Sbjct: 522 GMIHRQGTLHVGDEIREINGISVANQTVEQLQKMLREMRGSITFKIVPSYRTQSSSCERD 581
Query: 259 ----SRTSGSSG-QSTDNSLLGYPQQIEP 282
SR S ++G ST+NS+ P +P
Sbjct: 582 SPSTSRQSPANGHSSTNNSVSDLPSTTQP 610
>gi|110346438 FERM and PDZ domain containing 2 isoform 1 [Homo
sapiens]
Length = 1287
Score = 50.4 bits (119), Expect = 2e-06
Identities = 50/190 (26%), Positives = 81/190 (42%), Gaps = 33/190 (17%)
Query: 124 NHRKKPHIVISMPQDFRPVSSIIDVDILPETHRRVRLYKYGTEKPLGFYIRDGSSVRVTP 183
N+R+K I P I+ V + + HR GF I +G
Sbjct: 737 NNRRKSFIA-------EPGREIVRVTLKRDPHRG-----------FGFVINEGE------ 772
Query: 184 HGLEKVPGIFISRLVPGGLAQSTGLLAVNDEVLEVNGIEVSGKSLDQVTDMMIANSRN-- 241
+ + PGIFIS ++PGG A+ + ++L +N I + G + + MI NS +
Sbjct: 773 YSGQADPGIFISSIIPGGPAEKAKTIKPGGQILALNHISLEGFTFNMAV-RMIQNSPDNI 831
Query: 242 -LIITVRPANQRNNVVRNSRTSGSSG-QSTDNSLLGYPQQIEPSFEPEDEDSEEDDIIIE 299
LII+ NN ++ +SG STD GY + + +D ++EE D+
Sbjct: 832 ELIISQSKGVGGNNPDEEKNSTANSGVSSTDILSFGYQGSLLSHTQDQDRNTEELDMA-- 889
Query: 300 DNGVPQQIPK 309
GV +P+
Sbjct: 890 --GVQSLVPR 897
Score = 36.6 bits (83), Expect = 0.037
Identities = 21/67 (31%), Positives = 35/67 (52%), Gaps = 6/67 (8%)
Query: 169 LGFYIRDGSSVRVTPHGLEKVPGIFISRLVPGGLAQSTGLLAVNDEVLEVNGIEVSGKSL 228
LGF + G + V P+G GI++ +VPGG A G + D +L+V+G+ + G +
Sbjct: 938 LGFSVTGGINTSV-PYG-----GIYVKSIVPGGPAAKEGQILQGDRLLQVDGVILCGLTH 991
Query: 229 DQVTDMM 235
Q +
Sbjct: 992 KQAVQCL 998
Score = 31.2 bits (69), Expect = 1.6
Identities = 15/42 (35%), Positives = 21/42 (50%)
Query: 194 ISRLVPGGLAQSTGLLAVNDEVLEVNGIEVSGKSLDQVTDMM 235
I RL PG A+ G +A D +L VNG G +V ++
Sbjct: 1089 IKRLFPGQPAEENGAIAAGDIILAVNGRSTEGLIFQEVLHLL 1130
>gi|110346436 FERM and PDZ domain containing 2 isoform 3 [Homo
sapiens]
Length = 1309
Score = 50.4 bits (119), Expect = 2e-06
Identities = 50/190 (26%), Positives = 81/190 (42%), Gaps = 33/190 (17%)
Query: 124 NHRKKPHIVISMPQDFRPVSSIIDVDILPETHRRVRLYKYGTEKPLGFYIRDGSSVRVTP 183
N+R+K I P I+ V + + HR GF I +G
Sbjct: 759 NNRRKSFIA-------EPGREIVRVTLKRDPHRG-----------FGFVINEGE------ 794
Query: 184 HGLEKVPGIFISRLVPGGLAQSTGLLAVNDEVLEVNGIEVSGKSLDQVTDMMIANSRN-- 241
+ + PGIFIS ++PGG A+ + ++L +N I + G + + MI NS +
Sbjct: 795 YSGQADPGIFISSIIPGGPAEKAKTIKPGGQILALNHISLEGFTFNMAV-RMIQNSPDNI 853
Query: 242 -LIITVRPANQRNNVVRNSRTSGSSG-QSTDNSLLGYPQQIEPSFEPEDEDSEEDDIIIE 299
LII+ NN ++ +SG STD GY + + +D ++EE D+
Sbjct: 854 ELIISQSKGVGGNNPDEEKNSTANSGVSSTDILSFGYQGSLLSHTQDQDRNTEELDMA-- 911
Query: 300 DNGVPQQIPK 309
GV +P+
Sbjct: 912 --GVQSLVPR 919
Score = 36.6 bits (83), Expect = 0.037
Identities = 21/67 (31%), Positives = 35/67 (52%), Gaps = 6/67 (8%)
Query: 169 LGFYIRDGSSVRVTPHGLEKVPGIFISRLVPGGLAQSTGLLAVNDEVLEVNGIEVSGKSL 228
LGF + G + V P+G GI++ +VPGG A G + D +L+V+G+ + G +
Sbjct: 960 LGFSVTGGINTSV-PYG-----GIYVKSIVPGGPAAKEGQILQGDRLLQVDGVILCGLTH 1013
Query: 229 DQVTDMM 235
Q +
Sbjct: 1014 KQAVQCL 1020
Score = 31.2 bits (69), Expect = 1.6
Identities = 15/42 (35%), Positives = 21/42 (50%)
Query: 194 ISRLVPGGLAQSTGLLAVNDEVLEVNGIEVSGKSLDQVTDMM 235
I RL PG A+ G +A D +L VNG G +V ++
Sbjct: 1111 IKRLFPGQPAEENGAIAAGDIILAVNGRSTEGLIFQEVLHLL 1152
>gi|14780902 membrane protein, palmitoylated 4 [Homo sapiens]
Length = 637
Score = 49.3 bits (116), Expect = 6e-06
Identities = 32/115 (27%), Positives = 59/115 (51%), Gaps = 12/115 (10%)
Query: 137 QDFRPVSSIIDVDILPETHRRVRLY-KYGTEKPLGFYIRDGSSVRVTPHGLEKVPGIFIS 195
+DF P+ + D +PE+ +R+ ++PLG I+ E I ++
Sbjct: 132 KDFEPLLPPLP-DNIPESEEAMRIVCLVKNQQPLGATIKRH----------EMTGDILVA 180
Query: 196 RLVPGGLAQSTGLLAVNDEVLEVNGIEVSGKSLDQVTDMMIANSRNLIITVRPAN 250
R++ GGLA+ +GLL D+++EVNG+ V G +QV ++ + ++ V P +
Sbjct: 181 RIIHGGLAERSGLLYAGDKLVEVNGVSVEGLDPEQVIHILAMSRGTIMFKVVPVS 235
>gi|8922944 lin-7 homolog C [Homo sapiens]
Length = 197
Score = 48.5 bits (114), Expect = 9e-06
Identities = 28/83 (33%), Positives = 45/83 (54%), Gaps = 9/83 (10%)
Query: 165 TEKPLGFYIRDGSSVRVTPHGLEKVPGIFISRLVPGGLAQSTGLLAVNDEVLEVNGIEVS 224
TE+ LGF I G E+ I+ISR++PGG+A G L D++L VNG+ V
Sbjct: 99 TEEGLGFNIMGGK---------EQNSPIYISRIIPGGIADRHGGLKRGDQLLSVNGVSVE 149
Query: 225 GKSLDQVTDMMIANSRNLIITVR 247
G+ ++ +++ A + + VR
Sbjct: 150 GEHHEKAVELLKAAQGKVKLVVR 172
>gi|186700629 calcium/calmodulin-dependent serine protein kinase
isoform 3 [Homo sapiens]
Length = 897
Score = 47.8 bits (112), Expect = 2e-05
Identities = 35/163 (21%), Positives = 79/163 (48%), Gaps = 20/163 (12%)
Query: 141 PVSSIIDVDILPETHRRVRLYKYGTEKPLGFYIRDGSSVRVTPHGLEKVPGIFISRLVPG 200
P S+ D+D+ T R+ ++ T++P+G ++ + ++ ++R++ G
Sbjct: 467 PESANGDMDMENVTRVRLVQFQKNTDEPMGITLK-----------MNELNHCIVARIMHG 515
Query: 201 GLAQSTGLLAVNDEVLEVNGIEVSGKSLDQVTDMMIANSRNLIITVRPANQRNNVVRNSR 260
G+ G L V DE+ E+NGI V+ ++++Q+ M+ ++ + P + R
Sbjct: 516 GMIHRQGTLHVGDEIREINGISVANQTVEQLQKMLREMRGSITFKIVP---------SYR 566
Query: 261 TSGSSGQSTDNSLLGYPQQIEPSFEPEDEDSEEDDIIIEDNGV 303
T SS + ++ +QI + E + +++D I ++ G+
Sbjct: 567 TQSSSCEDLPSTTQPKGRQIYVRAQFEYDPAKDDLIPCKEAGI 609
>gi|186700627 calcium/calmodulin-dependent serine protein kinase
isoform 2 [Homo sapiens]
Length = 898
Score = 47.8 bits (112), Expect = 2e-05
Identities = 35/163 (21%), Positives = 79/163 (48%), Gaps = 20/163 (12%)
Query: 141 PVSSIIDVDILPETHRRVRLYKYGTEKPLGFYIRDGSSVRVTPHGLEKVPGIFISRLVPG 200
P S+ D+D+ T R+ ++ T++P+G ++ + ++ ++R++ G
Sbjct: 473 PESANGDMDMENVTRVRLVQFQKNTDEPMGITLK-----------MNELNHCIVARIMHG 521
Query: 201 GLAQSTGLLAVNDEVLEVNGIEVSGKSLDQVTDMMIANSRNLIITVRPANQRNNVVRNSR 260
G+ G L V DE+ E+NGI V+ ++++Q+ M+ ++ + P + R
Sbjct: 522 GMIHRQGTLHVGDEIREINGISVANQTVEQLQKMLREMRGSITFKIVP---------SYR 572
Query: 261 TSGSSGQSTDNSLLGYPQQIEPSFEPEDEDSEEDDIIIEDNGV 303
T SS + ++ +QI + E + +++D I ++ G+
Sbjct: 573 TQSSSCEDLPSTTQPKGRQIYVRAQFEYDPAKDDLIPCKEAGI 615
>gi|4759306 lin-7 homolog A [Homo sapiens]
Length = 233
Score = 47.8 bits (112), Expect = 2e-05
Identities = 26/83 (31%), Positives = 47/83 (56%), Gaps = 9/83 (10%)
Query: 165 TEKPLGFYIRDGSSVRVTPHGLEKVPGIFISRLVPGGLAQSTGLLAVNDEVLEVNGIEVS 224
T++ LGF + G E+ I+ISR++PGG+A+ G L D++L VNG+ V
Sbjct: 114 TDEGLGFNVMGGK---------EQNSPIYISRIIPGGVAERHGGLKRGDQLLSVNGVSVE 164
Query: 225 GKSLDQVTDMMIANSRNLIITVR 247
G+ ++ +++ A ++ + VR
Sbjct: 165 GEHHEKAVELLKAAKDSVKLVVR 187
>gi|45827729 scribble isoform b [Homo sapiens]
Length = 1630
Score = 47.8 bits (112), Expect = 2e-05
Identities = 28/80 (35%), Positives = 41/80 (51%), Gaps = 3/80 (3%)
Query: 165 TEKPLGFYIRDGSSVRVTPHGLEKVPGIFISRLVPGGLAQSTGLLAVNDEVLEVNGIEVS 224
+E+ LGF I G TP+ GIF+SR+ GG A G L V D VL +NG++V+
Sbjct: 868 SERGLGFSIAGGKGS--TPYRAGDA-GIFVSRIAEGGAAHRAGTLQVGDRVLSINGVDVT 924
Query: 225 GKSLDQVTDMMIANSRNLII 244
D ++ A S + +
Sbjct: 925 EARHDHAVSLLTAASPTIAL 944
Score = 47.8 bits (112), Expect = 2e-05
Identities = 33/96 (34%), Positives = 50/96 (52%), Gaps = 4/96 (4%)
Query: 152 PETHRRVRLYKYGTEKPLGFYIRDGSSVRVTPHGLEKVPGIFISRLVPGGLAQSTGLLAV 211
P +RL + G PLG I GS P G+++ PG+FIS+++P GLA +G L V
Sbjct: 999 PYPVEEIRLPRAGG--PLGLSIVGGSDHSSHPFGVQE-PGVFISKVLPRGLAARSG-LRV 1054
Query: 212 NDEVLEVNGIEVSGKSLDQVTDMMIANSRNLIITVR 247
D +L VNG +V + + ++ L + VR
Sbjct: 1055 GDRILAVNGQDVRDATHQEAVSALLRPCLELSLLVR 1090
Score = 31.6 bits (70), Expect = 1.2
Identities = 17/35 (48%), Positives = 23/35 (65%), Gaps = 1/35 (2%)
Query: 191 GIFISRLVPGGLAQSTGLLAVNDEVLEVNGIEVSG 225
GIFISR+ G A G+ V D++LEVNG+ + G
Sbjct: 757 GIFISRVSEEGPAARAGV-RVGDKLLEVNGVALQG 790
Score = 31.6 bits (70), Expect = 1.2
Identities = 29/105 (27%), Positives = 46/105 (43%), Gaps = 1/105 (0%)
Query: 142 VSSIIDVDILPETHRRVRLYKYGTEKPLGFYIRDGSSVRVTPHGLEKVPGIFISRLVPGG 201
+S ++ D P R + + K E+ LG IR G+ GIFIS++ P G
Sbjct: 1085 LSLLVRRDPAPPGLRELCIQKAPGER-LGISIRGGARGHAGNPRDPTDEGIFISKVSPTG 1143
Query: 202 LAQSTGLLAVNDEVLEVNGIEVSGKSLDQVTDMMIANSRNLIITV 246
A G L V +LEVN + G + + ++ + L + V
Sbjct: 1144 AAGRDGRLRVGLRLLEVNQQSLLGLTHGEAVQLLRSVGDTLTVLV 1188
>gi|45827731 scribble isoform a [Homo sapiens]
Length = 1655
Score = 47.8 bits (112), Expect = 2e-05
Identities = 28/80 (35%), Positives = 41/80 (51%), Gaps = 3/80 (3%)
Query: 165 TEKPLGFYIRDGSSVRVTPHGLEKVPGIFISRLVPGGLAQSTGLLAVNDEVLEVNGIEVS 224
+E+ LGF I G TP+ GIF+SR+ GG A G L V D VL +NG++V+
Sbjct: 868 SERGLGFSIAGGKGS--TPYRAGDA-GIFVSRIAEGGAAHRAGTLQVGDRVLSINGVDVT 924
Query: 225 GKSLDQVTDMMIANSRNLII 244
D ++ A S + +
Sbjct: 925 EARHDHAVSLLTAASPTIAL 944
Score = 47.8 bits (112), Expect = 2e-05
Identities = 33/96 (34%), Positives = 50/96 (52%), Gaps = 4/96 (4%)
Query: 152 PETHRRVRLYKYGTEKPLGFYIRDGSSVRVTPHGLEKVPGIFISRLVPGGLAQSTGLLAV 211
P +RL + G PLG I GS P G+++ PG+FIS+++P GLA +G L V
Sbjct: 999 PYPVEEIRLPRAGG--PLGLSIVGGSDHSSHPFGVQE-PGVFISKVLPRGLAARSG-LRV 1054
Query: 212 NDEVLEVNGIEVSGKSLDQVTDMMIANSRNLIITVR 247
D +L VNG +V + + ++ L + VR
Sbjct: 1055 GDRILAVNGQDVRDATHQEAVSALLRPCLELSLLVR 1090
Score = 31.6 bits (70), Expect = 1.2
Identities = 17/35 (48%), Positives = 23/35 (65%), Gaps = 1/35 (2%)
Query: 191 GIFISRLVPGGLAQSTGLLAVNDEVLEVNGIEVSG 225
GIFISR+ G A G+ V D++LEVNG+ + G
Sbjct: 757 GIFISRVSEEGPAARAGV-RVGDKLLEVNGVALQG 790
Score = 31.6 bits (70), Expect = 1.2
Identities = 29/105 (27%), Positives = 46/105 (43%), Gaps = 1/105 (0%)
Query: 142 VSSIIDVDILPETHRRVRLYKYGTEKPLGFYIRDGSSVRVTPHGLEKVPGIFISRLVPGG 201
+S ++ D P R + + K E+ LG IR G+ GIFIS++ P G
Sbjct: 1085 LSLLVRRDPAPPGLRELCIQKAPGER-LGISIRGGARGHAGNPRDPTDEGIFISKVSPTG 1143
Query: 202 LAQSTGLLAVNDEVLEVNGIEVSGKSLDQVTDMMIANSRNLIITV 246
A G L V +LEVN + G + + ++ + L + V
Sbjct: 1144 AAGRDGRLRVGLRLLEVNQQSLLGLTHGEAVQLLRSVGDTLTVLV 1188
>gi|218156340 chapsyn-110 isoform 3 [Homo sapiens]
Length = 749
Score = 47.4 bits (111), Expect = 2e-05
Identities = 27/67 (40%), Positives = 39/67 (58%), Gaps = 4/67 (5%)
Query: 169 LGFYIRDGSSVRVTPHGLEKVPGIFISRLVPGGLAQSTGLLAVNDEVLEVNGIEVSGKSL 228
LGF I G+ PH + PGIFI++++PGG A G L VND +L VN ++VS S
Sbjct: 57 LGFSIAGGTD---NPH-IGDDPGIFITKIIPGGAAAEDGRLRVNDCILRVNEVDVSEVSH 112
Query: 229 DQVTDMM 235
+ + +
Sbjct: 113 SKAVEAL 119
Score = 40.4 bits (93), Expect = 0.003
Identities = 36/127 (28%), Positives = 57/127 (44%), Gaps = 24/127 (18%)
Query: 156 RRVRLYKYGTEKPLGFYIRDGSSVRVTPHGLEKVPGIFISRLVPGGLAQSTGLLAVNDEV 215
R+V L+K T LGF I G E GIF+S ++ GG A +G L D++
Sbjct: 317 RKVVLHKGSTG--LGFNIVGG----------EDGEGIFVSFILAGGPADLSGELQRGDQI 364
Query: 216 LEVNGIEVSGKSLDQVTDMMIANSRNLIITVRPANQ------------RNNVVRNSRTSG 263
L VNGI++ G S +Q + + + I + + R ++ +S +SG
Sbjct: 365 LSVNGIDLRGASHEQAAAALKGAGQTVTIIAQYQPEDYARFEAKIHDLREQMMNHSMSSG 424
Query: 264 SSGQSTD 270
S T+
Sbjct: 425 SGSLRTN 431
>gi|218156338 chapsyn-110 isoform 1 [Homo sapiens]
Length = 975
Score = 47.4 bits (111), Expect = 2e-05
Identities = 27/67 (40%), Positives = 39/67 (58%), Gaps = 4/67 (5%)
Query: 169 LGFYIRDGSSVRVTPHGLEKVPGIFISRLVPGGLAQSTGLLAVNDEVLEVNGIEVSGKSL 228
LGF I G+ PH + PGIFI++++PGG A G L VND +L VN ++VS S
Sbjct: 213 LGFSIAGGTD---NPH-IGDDPGIFITKIIPGGAAAEDGRLRVNDCILRVNEVDVSEVSH 268
Query: 229 DQVTDMM 235
+ + +
Sbjct: 269 SKAVEAL 275
Score = 40.4 bits (93), Expect = 0.003
Identities = 36/127 (28%), Positives = 57/127 (44%), Gaps = 24/127 (18%)
Query: 156 RRVRLYKYGTEKPLGFYIRDGSSVRVTPHGLEKVPGIFISRLVPGGLAQSTGLLAVNDEV 215
R+V L+K T LGF I G E GIF+S ++ GG A +G L D++
Sbjct: 525 RKVVLHKGSTG--LGFNIVGG----------EDGEGIFVSFILAGGPADLSGELQRGDQI 572
Query: 216 LEVNGIEVSGKSLDQVTDMMIANSRNLIITVRPANQ------------RNNVVRNSRTSG 263
L VNGI++ G S +Q + + + I + + R ++ +S +SG
Sbjct: 573 LSVNGIDLRGASHEQAAAALKGAGQTVTIIAQYQPEDYARFEAKIHDLREQMMNHSMSSG 632
Query: 264 SSGQSTD 270
S T+
Sbjct: 633 SGSLRTN 639
>gi|91199538 chapsyn-110 isoform 2 [Homo sapiens]
Length = 870
Score = 47.4 bits (111), Expect = 2e-05
Identities = 27/67 (40%), Positives = 39/67 (58%), Gaps = 4/67 (5%)
Query: 169 LGFYIRDGSSVRVTPHGLEKVPGIFISRLVPGGLAQSTGLLAVNDEVLEVNGIEVSGKSL 228
LGF I G+ PH + PGIFI++++PGG A G L VND +L VN ++VS S
Sbjct: 108 LGFSIAGGTD---NPH-IGDDPGIFITKIIPGGAAAEDGRLRVNDCILRVNEVDVSEVSH 163
Query: 229 DQVTDMM 235
+ + +
Sbjct: 164 SKAVEAL 170
Score = 40.4 bits (93), Expect = 0.003
Identities = 36/127 (28%), Positives = 57/127 (44%), Gaps = 24/127 (18%)
Query: 156 RRVRLYKYGTEKPLGFYIRDGSSVRVTPHGLEKVPGIFISRLVPGGLAQSTGLLAVNDEV 215
R+V L+K T LGF I G E GIF+S ++ GG A +G L D++
Sbjct: 420 RKVVLHKGSTG--LGFNIVGG----------EDGEGIFVSFILAGGPADLSGELQRGDQI 467
Query: 216 LEVNGIEVSGKSLDQVTDMMIANSRNLIITVRPANQ------------RNNVVRNSRTSG 263
L VNGI++ G S +Q + + + I + + R ++ +S +SG
Sbjct: 468 LSVNGIDLRGASHEQAAAALKGAGQTVTIIAQYQPEDYARFEAKIHDLREQMMNHSMSSG 527
Query: 264 SSGQSTD 270
S T+
Sbjct: 528 SGSLRTN 534
>gi|11545920 lin-7 homolog B [Homo sapiens]
Length = 207
Score = 47.4 bits (111), Expect = 2e-05
Identities = 27/83 (32%), Positives = 46/83 (55%), Gaps = 9/83 (10%)
Query: 165 TEKPLGFYIRDGSSVRVTPHGLEKVPGIFISRLVPGGLAQSTGLLAVNDEVLEVNGIEVS 224
T++ LGF I G E+ I+ISR++PGG+A G L D++L VNG+ V
Sbjct: 99 TDEGLGFNIMGGK---------EQNSPIYISRVIPGGVADRHGGLKRGDQLLSVNGVSVE 149
Query: 225 GKSLDQVTDMMIANSRNLIITVR 247
G+ ++ +++ A ++ + VR
Sbjct: 150 GEQHEKAVELLKAAQGSVKLVVR 172
>gi|148746189 multiple PDZ domain protein [Homo sapiens]
Length = 2041
Score = 46.6 bits (109), Expect = 4e-05
Identities = 38/147 (25%), Positives = 64/147 (43%), Gaps = 26/147 (17%)
Query: 138 DFRPVSSIIDVDILPETHRRVRLYKYGTEKP-----------LGFYIRDGSSVRVTPHGL 186
D R + +++L +T +RVRL Y E P + + G + ++ G
Sbjct: 1684 DLRKATHDEAINVLRQTPQRVRLTLYRDEAPYKEEEVCDTLTIELQKKPGKGLGLSIVGK 1743
Query: 187 EKVPGIFISRLVPGGLAQSTGLLAVNDEVLEVNGIEVSGKSLDQVTDMMIANSRNLIITV 246
G+F+S +V GG+A + G L D++L VNG +V + + V ++ + +L
Sbjct: 1744 RNDTGVFVSDIVKGGIADADGRLMQGDQILMVNGEDVRNATQEAVAALLKVSEGSL---- 1799
Query: 247 RPANQRNNVVRNSRTSGSSGQSTDNSL 273
+S T SG ST SL
Sbjct: 1800 -----------SSFTFPLSGSSTSESL 1815
Score = 40.8 bits (94), Expect = 0.002
Identities = 33/131 (25%), Positives = 57/131 (43%), Gaps = 10/131 (7%)
Query: 173 IRDGSSVRVTPHGLEKVPGIFISRLVPGGLAQSTGLLAVNDEVLEVNGIEVSGKSLDQVT 232
+ DGS + G K G+ + ++PGG+A G L D +L++ +++G S +QV
Sbjct: 261 VNDGSGLGFGIIG-GKATGVIVKTILPGGVADQHGRLCSGDHILKIGDTDLAGMSSEQVA 319
Query: 233 DMM--IANSRNLIITVRPANQRNNVVRNSRTSGSSGQSTDNSLLGYPQQIEPSFEPEDED 290
++ N L+I +R T SS ST P+ + + E+
Sbjct: 320 QVLRQCGNRVKLMIARGAIEERTAPTALGITLSSSPTST-------PELRVDASTQKGEE 372
Query: 291 SEEDDIIIEDN 301
SE D+ + N
Sbjct: 373 SETFDVELTKN 383
Score = 40.8 bits (94), Expect = 0.002
Identities = 41/171 (23%), Positives = 66/171 (38%), Gaps = 22/171 (12%)
Query: 192 IFISRLVPGGLAQSTGLLAVNDEVLEVNGIEVSGKSLDQVTDMMIANSRNLIITVRPANQ 251
+FI + P G A G L + DE+LE+NG + G+S + II P+
Sbjct: 1375 VFIVGIDPNGAAGKDGRLQIADELLEINGQILYGRSHQNASS---------IIKCAPSKV 1425
Query: 252 RNNVVRNSRTSGSSGQSTDNSLLGYPQQIEPSFEPEDEDSEEDDIIIEDNGVPQQIPKAV 311
+ +RN N++ P E E E + + D A
Sbjct: 1426 KIIFIRNKDAVNQMAVCPGNAVEPLPSNSENLQNKETEPT----VTTSD---------AA 1472
Query: 312 PNTESLESLTQIELSFESGQNGFIPSNEVSLAAIASSSNTEFETHAPDQKL 362
+ S +++ +EL + G G S E +L+ + S TE A D +L
Sbjct: 1473 VDLSSFKNVQHLELPKDQGGLGIAISEEDTLSGVIIKSLTEHGVAATDGRL 1523
Score = 39.3 bits (90), Expect = 0.006
Identities = 34/150 (22%), Positives = 59/150 (39%), Gaps = 6/150 (4%)
Query: 187 EKVPGIFISRLVPGGLAQSTGLLAVNDEVLEVNGIEVSGKSLDQVTDMMIANSRNLIITV 246
+ + G+ I L G+A + G L V D++L V+ V G +++ ++ + +T+
Sbjct: 1501 DTLSGVIIKSLTEHGVAATDGRLKVGDQILAVDDEIVVGYPIEKFISLLKTAKMTVKLTI 1560
Query: 247 RPANQRNNVVRNSRTSGSSGQSTDNSLLGYPQQIEPSFEPED----EDSEEDDIIIEDNG 302
N + V ++ + S + + L PQ P EPE S I D
Sbjct: 1561 HAENPDSQAVPSAAGAASGEKKNSSQSLMVPQSGSP--EPESIRNTSRSSTPAIFASDPA 1618
Query: 303 VPQQIPKAVPNTESLESLTQIELSFESGQN 332
IP E + T + LS G +
Sbjct: 1619 TCPIIPGCETTIEISKGRTGLGLSIVGGSD 1648
Score = 35.0 bits (79), Expect = 0.11
Identities = 15/44 (34%), Positives = 25/44 (56%)
Query: 192 IFISRLVPGGLAQSTGLLAVNDEVLEVNGIEVSGKSLDQVTDMM 235
I I LVPGG+A+ G L D ++ VN + + SL++ + +
Sbjct: 728 IIIRSLVPGGIAEKDGRLLPGDRLMFVNDVNLENSSLEEAVEAL 771
Score = 33.9 bits (76), Expect = 0.24
Identities = 23/78 (29%), Positives = 38/78 (48%), Gaps = 1/78 (1%)
Query: 156 RRVRLYKYGTEKPLGFYIRDGSSVRVTPHGLEKVPGIFISRLVPGGLAQSTGLLAVNDEV 215
RRV L++ + K LG I G + E + GIFI ++ A G L D +
Sbjct: 1150 RRVELWREPS-KSLGISIVGGRGMGSRLSNGEVMRGIFIKHVLEDSPAGKNGTLKPGDRI 1208
Query: 216 LEVNGIEVSGKSLDQVTD 233
+EV+G+++ S +Q +
Sbjct: 1209 VEVDGMDLRDASHEQAVE 1226
Score = 32.3 bits (72), Expect = 0.70
Identities = 16/43 (37%), Positives = 26/43 (60%)
Query: 193 FISRLVPGGLAQSTGLLAVNDEVLEVNGIEVSGKSLDQVTDMM 235
FI ++P G +G L DE+LEVNGI + G++ V +++
Sbjct: 577 FIRSVLPEGPVGHSGKLFSGDELLEVNGITLLGENHQDVVNIL 619
Score = 32.0 bits (71), Expect = 0.92
Identities = 31/139 (22%), Positives = 58/139 (41%), Gaps = 13/139 (9%)
Query: 111 KKKNVLTNVLRPDNHRKKPHIVISMPQDFRPVSSIID---VDILPETHRRVRLYKYGTEK 167
+KKN +++ P + +P + + + P D I+P + + K T
Sbjct: 1580 EKKNSSQSLMVPQSGSPEPESIRNTSRSSTPAIFASDPATCPIIPGCETTIEISKGRTG- 1638
Query: 168 PLGFYIRDGSSVRVTPHGLEKVPGIFISRLVPGGLAQSTGLLAVNDEVLEVNGIEVSGKS 227
LG I GS + I I + G A G L D++LEVNGI++ +
Sbjct: 1639 -LGLSIVGGSDTLLG--------AIIIHEVYEEGAACKDGRLWAGDQILEVNGIDLRKAT 1689
Query: 228 LDQVTDMMIANSRNLIITV 246
D+ +++ + + +T+
Sbjct: 1690 HDEAINVLRQTPQRVRLTL 1708
Score = 30.8 bits (68), Expect = 2.0
Identities = 12/70 (17%), Positives = 32/70 (45%)
Query: 191 GIFISRLVPGGLAQSTGLLAVNDEVLEVNGIEVSGKSLDQVTDMMIANSRNLIITVRPAN 250
GIF+ + + G + + D+++ V+G + G + Q +++ + +++T+
Sbjct: 404 GIFVKSITKSSAVEHDGRIQIGDQIIAVDGTNLQGFTNQQAVEVLRHTGQTVLLTLMRRG 463
Query: 251 QRNNVVRNSR 260
+ SR
Sbjct: 464 MKQEAELMSR 473
Score = 30.0 bits (66), Expect = 3.5
Identities = 35/125 (28%), Positives = 54/125 (43%), Gaps = 14/125 (11%)
Query: 162 KYGTEKPLGFYIRDGSSVRVTPHGLEKVPGIFISRLVPGGLAQSTGLLAVNDEVLEVNGI 221
K G LG I G +P G VP IFI+ + P G+A T L V D ++ + G
Sbjct: 1837 KKGPTDSLGISIAGGVG---SPLG--DVP-IFIAMMHPTGVAAQTQKLRVGDRIVTICGT 1890
Query: 222 EVSGKSLDQVTDMMIANSRNLIITVRPANQRNNVVRNSRTSGSSGQS----TDNSL---- 273
G + Q +++ S ++ + V + V + + SS S T +S+
Sbjct: 1891 STEGMTHTQAVNLLKNASGSIEMQVVAGGDVSVVTGHQQEPASSSLSFTGLTSSSIFQDD 1950
Query: 274 LGYPQ 278
LG PQ
Sbjct: 1951 LGPPQ 1955
>gi|119943106 synapse-associated protein 102 isoform a [Homo
sapiens]
Length = 817
Score = 46.2 bits (108), Expect = 5e-05
Identities = 27/56 (48%), Positives = 34/56 (60%), Gaps = 4/56 (7%)
Query: 169 LGFYIRDGSSVRVTPHGLEKVPGIFISRLVPGGLAQSTGLLAVNDEVLEVNGIEVS 224
LGF I G PH + PGIFI++++PGG A G L VND VL VN ++VS
Sbjct: 141 LGFSIAGGID---NPH-VPDDPGIFITKIIPGGAAAMDGRLGVNDCVLRVNEVDVS 192
Score = 38.9 bits (89), Expect = 0.008
Identities = 38/140 (27%), Positives = 62/140 (44%), Gaps = 19/140 (13%)
Query: 152 PETHRRVRLYKYGTEKPLGFYIRDGSSVRVTPHGLEKVPG---IFISRLVPGGLAQSTGL 208
PET V L K K LGF I G G + +PG I+I++++ GG AQ G
Sbjct: 221 PETIMEVNLLK--GPKGLGFSIAGGI-------GNQHIPGDNSIYITKIIEGGAAQKDGR 271
Query: 209 LAVNDEVLEVNGIEVSGKSLDQVTDMMIANSRNLIITV-RPANQRNNVV------RNSRT 261
L + D +L VN + ++ + S + + V +P + N + ++ T
Sbjct: 272 LQIGDRLLAVNNTNLQDVRHEEAVASLKNTSDMVYLKVAKPGSLHLNDMYAPPDYASTFT 331
Query: 262 SGSSGQSTDNSLLGYPQQIE 281
+ + + NS LGY +E
Sbjct: 332 ALADNHISHNSSLGYLGAVE 351
Score = 36.2 bits (82), Expect = 0.049
Identities = 34/126 (26%), Positives = 54/126 (42%), Gaps = 24/126 (19%)
Query: 156 RRVRLYKYGTEKPLGFYIRDGSSVRVTPHGLEKVPGIFISRLVPGGLAQSTGLLAVNDEV 215
R++ L+K T LGF I G E GIF+S ++ GG A +G L D +
Sbjct: 385 RKIILHKGSTG--LGFNIVGG----------EDGEGIFVSFILAGGPADLSGELRRGDRI 432
Query: 216 LEVNGIEVSGKSLDQVTDMM--IANSRNLIITVRPA----------NQRNNVVRNSRTSG 263
L VNG+ + + +Q + S ++ RP + R ++ +S +SG
Sbjct: 433 LSVNGVNLRNATHEQAAAALKRAGQSVTIVAQYRPEEYSRFESKIHDLREQMMNSSMSSG 492
Query: 264 SSGQST 269
S T
Sbjct: 493 SGSLRT 498
>gi|4505237 palmitoylated membrane protein 1 [Homo sapiens]
Length = 466
Score = 46.2 bits (108), Expect = 5e-05
Identities = 29/98 (29%), Positives = 49/98 (50%), Gaps = 13/98 (13%)
Query: 156 RRVRLYKYG--TEKPLGFYIRDGSSVRVTPHGLEKVPGIFISRLVPGGLAQSTGLLAVND 213
R+VRL ++ TE+P+G ++ L + ++R++ GG+ G L V D
Sbjct: 67 RKVRLIQFEKVTEEPMGITLK-----------LNEKQSCTVARILHGGMIHRQGSLHVGD 115
Query: 214 EVLEVNGIEVSGKSLDQVTDMMIANSRNLIITVRPANQ 251
E+LE+NG V+ S+DQ+ M + + V P Q
Sbjct: 116 EILEINGTNVTNHSVDQLQKAMKETKGMISLKVIPNQQ 153
>gi|31742501 sorting nexin family member 27 [Homo sapiens]
Length = 528
Score = 46.2 bits (108), Expect = 5e-05
Identities = 37/116 (31%), Positives = 61/116 (52%), Gaps = 10/116 (8%)
Query: 156 RRVRLYKYGTEKPLGFYIR----DGSSVRVTPHGLEKVPGIFISRLVPGGLAQSTGLLAV 211
R VR+ K +E GF +R +G +R + +G P +S ++PGG A G+
Sbjct: 42 RVVRIVK--SESGYGFNVRGQVSEGGQLR-SINGELYAPLQHVSAVLPGGAADRAGVRK- 97
Query: 212 NDEVLEVNGIEVSGKSLDQVTDMMIANSRNLIITVR--PANQRNNVVRNSRTSGSS 265
D +LEVN + V G + QV D++ A + LI+TV P ++ +N+ + + G S
Sbjct: 98 GDRILEVNHVNVEGATHKQVVDLIRAGEKELILTVLSVPPHEADNLDPSDDSLGQS 153
>gi|87196343 PDZ domain containing 2 [Homo sapiens]
Length = 2839
Score = 46.2 bits (108), Expect = 5e-05
Identities = 45/202 (22%), Positives = 91/202 (45%), Gaps = 22/202 (10%)
Query: 169 LGFYIRDGSSVRVTPHGLEKVPGIFISRLVPGGLAQSTGLLAVNDEVLEVNGIEVSGKSL 228
LG + G + +PH I ++++ GG A G L++ DE+L +NG + G S
Sbjct: 344 LGIQVSGGRGSKRSPHA------IVVTQVKEGGAAHRDGRLSLGDELLVINGHLLVGLSH 397
Query: 229 DQVTDMMIANSRNLIITVRPANQRNNVVRNSRTSGSSGQSTDNSLLGYPQQIEPSFEPED 288
++ + I S ++ + A++ N+ R + S +S+ + + + ED
Sbjct: 398 EEA--VAILRSATGMVQLVVASKENSAEDLLRLTSKSLPDLTSSV----EDVSSWTDNED 451
Query: 289 EDSEEDDIIIEDNGVPQQIPKAVPNTESLESLTQIELS---FESGQNGFIPSNEVSLAAI 345
++++ + ED G + +A+P T+ + + E S ES + G SN++ L +
Sbjct: 452 QEADGE----EDEGTSSSVQRAMPGTDEPQDVCGAEESKGNLESPKQG---SNKIKLKSR 504
Query: 346 ASSSNTEFETHAPDQKLLEEDG 367
S E+ +L+ +G
Sbjct: 505 LSGGVHRLESVEEYNELMVRNG 526
Score = 41.2 bits (95), Expect = 0.002
Identities = 40/139 (28%), Positives = 56/139 (40%), Gaps = 23/139 (16%)
Query: 150 ILPETHRRVRLYKYGTEKPLGFYIRDGSSVRVTPHGLEKVPGIFISRLVPGGLAQSTGLL 209
I P + LYK K LGF I G + GIF+ + P G A G L
Sbjct: 579 IRPSVISIIGLYKE-KGKGLGFSIAGGRDC------IRGQMGIFVKTIFPNGSAAEDGRL 631
Query: 210 AVNDEVLEVNGIEVSGKSLDQ-VTDMMIANSRNLIITVR-------------PANQRNNV 255
DE+L+VNGI + G + + + S ++TVR P + +
Sbjct: 632 KEGDEILDVNGIPIKGLTFQEAIHTFKQIRSGLFVLTVRTKLVSPSLTPCSTPTHMSRSA 691
Query: 256 VRNSRTSG--SSGQSTDNS 272
N TSG S+G S + S
Sbjct: 692 SPNFNTSGGASAGGSDEGS 710
Score = 37.4 bits (85), Expect = 0.022
Identities = 17/42 (40%), Positives = 26/42 (61%)
Query: 190 PGIFISRLVPGGLAQSTGLLAVNDEVLEVNGIEVSGKSLDQV 231
PGI+I L PG +A+ L+ D++LEVN + V +L +V
Sbjct: 753 PGIYIHSLAPGSVAKMESNLSRGDQILEVNSVNVRHAALSKV 794
Score = 32.0 bits (71), Expect = 0.92
Identities = 17/51 (33%), Positives = 25/51 (49%), Gaps = 5/51 (9%)
Query: 175 DGSSVRVTPHGLEKVPGIFISRLVPGGLAQSTGLLAVNDEVLEVNGIEVSG 225
DG VT G + I R+ GG A+ G++ DE+L +NG + G
Sbjct: 2765 DGGKSSVTGDG-----PLVIKRVYKGGAAEQAGIIEAGDEILAINGKPLVG 2810
>gi|218505835 membrane-associated guanylate kinase-related 3
isoform 1 [Homo sapiens]
Length = 1481
Score = 46.2 bits (108), Expect = 5e-05
Identities = 31/110 (28%), Positives = 53/110 (48%), Gaps = 6/110 (5%)
Query: 192 IFISRLVPGGLAQSTGLLAVNDEVLEVNGIEVSGKSLDQVTDMMIANSRN--LIITVRPA 249
I+I ++P G A+ G L DE++ ++GI V GKS QV D+M +RN +++TVR
Sbjct: 750 IYIGAIIPLGAAEKDGRLRAADELMCIDGIPVKGKSHKQVLDLMTTAARNGHVLLTVR-- 807
Query: 250 NQRNNVVRNSRTSGSSGQSTDNSLLGYPQQIEPSFEPEDEDSEEDDIIIE 299
R + S Q+ ++ G P+ E D++++
Sbjct: 808 --RKIFYGEKQPEDDSSQAFISTQNGSPRLNRAEVPARPAPQEPYDVVLQ 855
Score = 40.4 bits (93), Expect = 0.003
Identities = 32/151 (21%), Positives = 65/151 (43%), Gaps = 9/151 (5%)
Query: 185 GLEKVPGIFISRLVPGGLAQSTGLLAVNDEVLEVNGIEVSGKSLDQVTDMMIANSRNLII 244
G E G+FI RL G A G + V D+++E+NG G + + +++ A +++
Sbjct: 1038 GKEYNMGLFILRLAEDGPAIKDGRIHVGDQIVEINGEPTQGITHTRAIELIQAGGNKVLL 1097
Query: 245 TVRPANQRNNVVRNSRTSGSSGQSTDNSLLGYPQQIEPS------FEPEDEDSEEDDIII 298
+RP ++ + + S+ N + + PS FE E+ + +
Sbjct: 1098 LLRPG---TGLIPDHGDWDINNPSSSNVIYDEQSPLPPSSHFASIFEESHVPVIEESLRV 1154
Query: 299 EDNGVPQQIPKAVPNTESLESLTQIELSFES 329
+ +++ VP +S + Q E+ +S
Sbjct: 1155 QICEKAEELKDIVPEKKSTLNENQPEIKHQS 1185
>gi|155969695 membrane-associated guanylate kinase-related 3
isoform 2 [Homo sapiens]
Length = 1125
Score = 46.2 bits (108), Expect = 5e-05
Identities = 31/110 (28%), Positives = 53/110 (48%), Gaps = 6/110 (5%)
Query: 192 IFISRLVPGGLAQSTGLLAVNDEVLEVNGIEVSGKSLDQVTDMMIANSRN--LIITVRPA 249
I+I ++P G A+ G L DE++ ++GI V GKS QV D+M +RN +++TVR
Sbjct: 750 IYIGAIIPLGAAEKDGRLRAADELMCIDGIPVKGKSHKQVLDLMTTAARNGHVLLTVR-- 807
Query: 250 NQRNNVVRNSRTSGSSGQSTDNSLLGYPQQIEPSFEPEDEDSEEDDIIIE 299
R + S Q+ ++ G P+ E D++++
Sbjct: 808 --RKIFYGEKQPEDDSSQAFISTQNGSPRLNRAEVPARPAPQEPYDVVLQ 855
Score = 38.1 bits (87), Expect = 0.013
Identities = 19/64 (29%), Positives = 34/64 (53%)
Query: 185 GLEKVPGIFISRLVPGGLAQSTGLLAVNDEVLEVNGIEVSGKSLDQVTDMMIANSRNLII 244
G E G+FI RL G A G + V D+++E+NG G + + +++ A +++
Sbjct: 1038 GKEYNMGLFILRLAEDGPAIKDGRIHVGDQIVEINGEPTQGITHTRAIELIQAGGNKVLL 1097
Query: 245 TVRP 248
+RP
Sbjct: 1098 LLRP 1101
>gi|140561024 CASK-interacting protein CIP98 isoform 1 [Homo
sapiens]
Length = 907
Score = 45.8 bits (107), Expect = 6e-05
Identities = 32/91 (35%), Positives = 52/91 (57%), Gaps = 3/91 (3%)
Query: 158 VRLYKYGTEKPLGFYIRDGSSVRVTPHG-LEKVPGIFISRLVPGGLAQSTGLLAVNDEVL 216
+ L + G EK + + DG S+ +T G E GI+I+ + PG A+ +G L V D++L
Sbjct: 269 LHLLQGGDEKKVNLVLGDGRSLGLTIRGGAEYGLGIYITGVDPGSEAEGSG-LKVGDQIL 327
Query: 217 EVNGIEVSGKSLDQVTDMMIANSRNLIITVR 247
EVNG D+ ++ +SR+LI+TV+
Sbjct: 328 EVNGRSFLNILHDEAV-RLLKSSRHLILTVK 357
Score = 41.6 bits (96), Expect = 0.001
Identities = 36/104 (34%), Positives = 52/104 (50%), Gaps = 19/104 (18%)
Query: 152 PETHRRVRLYKYGTEKPLGFYIRDGSSVRVTPHGLEKVPGIFISRLVPGGLAQSTGLLAV 211
P R V L + + LGF IR GS HG+ GI++S + PG LA+ G L V
Sbjct: 135 PGEVRLVSLRRAKAHEGLGFSIRGGSE-----HGV----GIYVSLVEPGSLAEKEG-LRV 184
Query: 212 NDEVLEVNGIEVSGKSLDQVTD----MMIANSRNLIITVRPANQ 251
D++L VN KSL +VT + S+ L+++V A +
Sbjct: 185 GDQILRVN-----DKSLARVTHAEAVKALKGSKKLVLSVYSAGR 223
Score = 30.0 bits (66), Expect = 3.5
Identities = 25/77 (32%), Positives = 37/77 (48%), Gaps = 10/77 (12%)
Query: 150 ILPETHRRVRLYKYGTEKPLGFYIRDGSSVRVTPHGLEKVPGIFISRLVPGGLAQSTGLL 209
+L T VR+ K + LG I G++ R + +P I + GG A + G L
Sbjct: 809 LLEPTSTLVRVKK--SAATLGIAIEGGANTR------QPLPRIVT--IQRGGSAHNCGQL 858
Query: 210 AVNDEVLEVNGIEVSGK 226
V +LEVNG+ + GK
Sbjct: 859 KVGHVILEVNGLTLRGK 875
>gi|24025688 ligand of numb-protein X 2 [Homo sapiens]
Length = 690
Score = 45.4 bits (106), Expect = 8e-05
Identities = 27/80 (33%), Positives = 43/80 (53%), Gaps = 2/80 (2%)
Query: 190 PGIFISRLVPGGLAQSTGLLAVNDEVLEVNGIEVSGKSLDQVTDMMIANSRNLIITV-RP 248
PG+FI L+ GGLA G L+ ND VL +NG ++ + + ++ A+ + +T+ RP
Sbjct: 362 PGVFILDLLEGGLAAQDGRLSSNDRVLAINGHDLKYGTPELAAQIIQASGERVNLTIARP 421
Query: 249 AN-QRNNVVRNSRTSGSSGQ 267
Q N +R + SS Q
Sbjct: 422 GKPQPGNTIREAGNHSSSSQ 441
Score = 28.9 bits (63), Expect = 7.8
Identities = 13/56 (23%), Positives = 30/56 (53%)
Query: 192 IFISRLVPGGLAQSTGLLAVNDEVLEVNGIEVSGKSLDQVTDMMIANSRNLIITVR 247
IF++ + P G G + D +L +NGI+++ S + M+ A++ + + ++
Sbjct: 496 IFVTSVPPHGCLARDGRIKRGDVLLNINGIDLTNLSHSEAVAMLKASAASPAVALK 551
>gi|111154074 palmitoylated membrane protein 7 [Homo sapiens]
Length = 576
Score = 45.1 bits (105), Expect = 1e-04
Identities = 28/105 (26%), Positives = 53/105 (50%), Gaps = 12/105 (11%)
Query: 147 DVDILPETHRRVRLYKYGTEKPLGFYIRDGSSVRVTPHGLEKVPGIFISRLVPGGLAQST 206
D+D ++ + +RL K +PLG I+ E+ I ++R++ GG A +
Sbjct: 129 DIDDEEDSVKIIRLVK--NREPLGATIKKD----------EQTGAIIVARIMRGGAADRS 176
Query: 207 GLLAVNDEVLEVNGIEVSGKSLDQVTDMMIANSRNLIITVRPANQ 251
GL+ V DE+ EVNGI V K +++ ++ + + + P ++
Sbjct: 177 GLIHVGDELREVNGIPVEDKRPEEIIQILAQSQGAITFKIIPGSK 221
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.314 0.134 0.377
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 14,230,983
Number of Sequences: 37866
Number of extensions: 662896
Number of successful extensions: 2174
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 96
Number of HSP's successfully gapped in prelim test: 61
Number of HSP's that attempted gapping in prelim test: 1926
Number of HSP's gapped (non-prelim): 284
length of query: 372
length of database: 18,247,518
effective HSP length: 104
effective length of query: 268
effective length of database: 14,309,454
effective search space: 3834933672
effective search space used: 3834933672
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.