BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|62821787 COBL-like 1 [Homo sapiens] (1166 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|62821787 COBL-like 1 [Homo sapiens] 2318 0.0 gi|31581524 cordon-bleu homolog [Homo sapiens] 232 1e-60 gi|148727245 thioredoxin domain-containing 2 isoform 1 [Homo sap... 57 1e-07 gi|148727319 thioredoxin domain-containing 2 isoform 2 [Homo sap... 57 1e-07 gi|42516570 thioredoxin domain-containing 2 isoform 1 [Homo sapi... 57 1e-07 gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens] 57 1e-07 gi|150170670 piccolo isoform 2 [Homo sapiens] 51 7e-06 gi|150378539 piccolo isoform 1 [Homo sapiens] 51 7e-06 gi|33620716 retinoblastoma-binding protein 6 isoform 2 [Homo sap... 50 2e-05 gi|33620769 retinoblastoma-binding protein 6 isoform 1 [Homo sap... 50 2e-05 gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens] 49 2e-05 gi|91982772 mucin 17 [Homo sapiens] 48 5e-05 gi|189181720 proteoglycan 4 isoform B [Homo sapiens] 47 1e-04 gi|67190163 proteoglycan 4 isoform A [Homo sapiens] 47 1e-04 gi|148596949 nucleolar and coiled-body phosphoprotein 1 [Homo sa... 45 4e-04 gi|55953110 retinoblastoma protein-binding zinc finger protein i... 45 4e-04 gi|20336260 retinoblastoma protein-binding zinc finger protein i... 45 4e-04 gi|20336258 retinoblastoma protein-binding zinc finger protein i... 45 4e-04 gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens] 45 5e-04 gi|132626688 mediator of DNA-damage checkpoint 1 [Homo sapiens] 44 7e-04 gi|239508790 PREDICTED: hypothetical protein, partial [Homo sapi... 44 9e-04 gi|222352122 hypothetical protein LOC284297 [Homo sapiens] 44 0.001 gi|237757326 synaptojanin 1 isoform d [Homo sapiens] 44 0.001 gi|118600981 jumonji domain containing 1C isoform a [Homo sapiens] 43 0.002 gi|68342036 jumonji domain containing 1C isoform b [Homo sapiens] 43 0.002 gi|7656879 ALL1 fused gene from 5q31 [Homo sapiens] 43 0.002 gi|189181724 proteoglycan 4 isoform D [Homo sapiens] 43 0.002 gi|189181722 proteoglycan 4 isoform C [Homo sapiens] 43 0.002 gi|157738649 neurofilament, medium polypeptide 150kDa isoform 1 ... 43 0.002 gi|157738641 neurofilament, medium polypeptide 150kDa isoform 2 ... 43 0.002 >gi|62821787 COBL-like 1 [Homo sapiens] Length = 1166 Score = 2318 bits (6006), Expect = 0.0 Identities = 1166/1166 (100%), Positives = 1166/1166 (100%) Query: 1 MDGRTPRPQDAPARRKPKAKAPLPPAETKYTDVSSAADSVESTAFIMEQKENMIDKDVEL 60 MDGRTPRPQDAPARRKPKAKAPLPPAETKYTDVSSAADSVESTAFIMEQKENMIDKDVEL Sbjct: 1 MDGRTPRPQDAPARRKPKAKAPLPPAETKYTDVSSAADSVESTAFIMEQKENMIDKDVEL 60 Query: 61 SVVLPGDIIKSTTVHGSKPMMDLLIFLCAQYHLNPSSYTIDLLSAEQNHIKFKPNTPIGM 120 SVVLPGDIIKSTTVHGSKPMMDLLIFLCAQYHLNPSSYTIDLLSAEQNHIKFKPNTPIGM Sbjct: 61 SVVLPGDIIKSTTVHGSKPMMDLLIFLCAQYHLNPSSYTIDLLSAEQNHIKFKPNTPIGM 120 Query: 121 LEVEKVILKPKMLDKKKPTPIIPEKTVRVVINFKKTQKTIVRVSPHASLQELAPIICSKC 180 LEVEKVILKPKMLDKKKPTPIIPEKTVRVVINFKKTQKTIVRVSPHASLQELAPIICSKC Sbjct: 121 LEVEKVILKPKMLDKKKPTPIIPEKTVRVVINFKKTQKTIVRVSPHASLQELAPIICSKC 180 Query: 181 EFDPLHTLLLKDYQSQEPLDLTKSLNDLGLRELYAMDVNRESCQISQNLDIMKEKENKGF 240 EFDPLHTLLLKDYQSQEPLDLTKSLNDLGLRELYAMDVNRESCQISQNLDIMKEKENKGF Sbjct: 181 EFDPLHTLLLKDYQSQEPLDLTKSLNDLGLRELYAMDVNRESCQISQNLDIMKEKENKGF 240 Query: 241 FSFFQRSKKKRDQTASAPATPLVNKHRPTFTRSNTISKPYISNTLPSDAPKKRRAPLPPM 300 FSFFQRSKKKRDQTASAPATPLVNKHRPTFTRSNTISKPYISNTLPSDAPKKRRAPLPPM Sbjct: 241 FSFFQRSKKKRDQTASAPATPLVNKHRPTFTRSNTISKPYISNTLPSDAPKKRRAPLPPM 300 Query: 301 PASQSVPQDLAHIQERPASCIVKSMSVDETDKSPCEAGRVRAGSLQLSSMSAGNSSLRRT 360 PASQSVPQDLAHIQERPASCIVKSMSVDETDKSPCEAGRVRAGSLQLSSMSAGNSSLRRT Sbjct: 301 PASQSVPQDLAHIQERPASCIVKSMSVDETDKSPCEAGRVRAGSLQLSSMSAGNSSLRRT 360 Query: 361 KRKAPSPPSKIPPHQSDENSRVTALQPVDGVPPDSASEANSPEELSSPETFHPGLSSQEQ 420 KRKAPSPPSKIPPHQSDENSRVTALQPVDGVPPDSASEANSPEELSSPETFHPGLSSQEQ Sbjct: 361 KRKAPSPPSKIPPHQSDENSRVTALQPVDGVPPDSASEANSPEELSSPETFHPGLSSQEQ 420 Query: 421 CTAPKLMEETSVFECPGTPEAAITSLTSGISSDYSLEEIDEKEELSEVPKVEAENISPKS 480 CTAPKLMEETSVFECPGTPEAAITSLTSGISSDYSLEEIDEKEELSEVPKVEAENISPKS Sbjct: 421 CTAPKLMEETSVFECPGTPEAAITSLTSGISSDYSLEEIDEKEELSEVPKVEAENISPKS 480 Query: 481 QDIPFVSTDIINTLKNDPDSALGNGSGEFSQNSMEEKQETKSTDGQEPHSVVYDTSNGKK 540 QDIPFVSTDIINTLKNDPDSALGNGSGEFSQNSMEEKQETKSTDGQEPHSVVYDTSNGKK Sbjct: 481 QDIPFVSTDIINTLKNDPDSALGNGSGEFSQNSMEEKQETKSTDGQEPHSVVYDTSNGKK 540 Query: 541 VVDSIRNLKSLGPNQENVQNEIIVYPENTEDNMKNGVKKTEINVEGVAKNNNIDMEVERP 600 VVDSIRNLKSLGPNQENVQNEIIVYPENTEDNMKNGVKKTEINVEGVAKNNNIDMEVERP Sbjct: 541 VVDSIRNLKSLGPNQENVQNEIIVYPENTEDNMKNGVKKTEINVEGVAKNNNIDMEVERP 600 Query: 601 SNSEAHETDTAISYKENHLAASSVPDQKLNQPSAEKTKDAAIQTTPSCNSFDGKHQDHNL 660 SNSEAHETDTAISYKENHLAASSVPDQKLNQPSAEKTKDAAIQTTPSCNSFDGKHQDHNL Sbjct: 601 SNSEAHETDTAISYKENHLAASSVPDQKLNQPSAEKTKDAAIQTTPSCNSFDGKHQDHNL 660 Query: 661 SDSKVEECVQTSNNNISTQHSCLSSQDSVNTSREFRSQGTLIIHSEDPLTVKDPICAHGN 720 SDSKVEECVQTSNNNISTQHSCLSSQDSVNTSREFRSQGTLIIHSEDPLTVKDPICAHGN Sbjct: 661 SDSKVEECVQTSNNNISTQHSCLSSQDSVNTSREFRSQGTLIIHSEDPLTVKDPICAHGN 720 Query: 721 DDLLPPVDRIDKNSTASYLKNYPLYRQDYNPKPKPSNEITREYIPKIGMTTYKIVPPKSL 780 DDLLPPVDRIDKNSTASYLKNYPLYRQDYNPKPKPSNEITREYIPKIGMTTYKIVPPKSL Sbjct: 721 DDLLPPVDRIDKNSTASYLKNYPLYRQDYNPKPKPSNEITREYIPKIGMTTYKIVPPKSL 780 Query: 781 EISKDWQSETIEYKDDQDMHALGKKHTHENVKETAIQTEDSAISESPEEPLPNLKPKPNL 840 EISKDWQSETIEYKDDQDMHALGKKHTHENVKETAIQTEDSAISESPEEPLPNLKPKPNL Sbjct: 781 EISKDWQSETIEYKDDQDMHALGKKHTHENVKETAIQTEDSAISESPEEPLPNLKPKPNL 840 Query: 841 RTEHQVPSSVSSPDDAMVSPLKPAPKMTRDTGTAPFAPNLEEINNILESKFKSRASNAQA 900 RTEHQVPSSVSSPDDAMVSPLKPAPKMTRDTGTAPFAPNLEEINNILESKFKSRASNAQA Sbjct: 841 RTEHQVPSSVSSPDDAMVSPLKPAPKMTRDTGTAPFAPNLEEINNILESKFKSRASNAQA 900 Query: 901 KPSSFFLQMQKRVSGHYVTSAAAKSVHAAPNPAPKELTNKEAERDMLPSPEQTLSPLSKM 960 KPSSFFLQMQKRVSGHYVTSAAAKSVHAAPNPAPKELTNKEAERDMLPSPEQTLSPLSKM Sbjct: 901 KPSSFFLQMQKRVSGHYVTSAAAKSVHAAPNPAPKELTNKEAERDMLPSPEQTLSPLSKM 960 Query: 961 PHSVPQPLVEKTDDDVIGQAPAEASPPPIAPKPVTIPASQVSTQNLKTLKTFGAPRPYSS 1020 PHSVPQPLVEKTDDDVIGQAPAEASPPPIAPKPVTIPASQVSTQNLKTLKTFGAPRPYSS Sbjct: 961 PHSVPQPLVEKTDDDVIGQAPAEASPPPIAPKPVTIPASQVSTQNLKTLKTFGAPRPYSS 1020 Query: 1021 SGPSPFALAVVKRSQSFSKERTESPSASALVQPPANTEEGKTHSVNKFVDIPQLGVSDKE 1080 SGPSPFALAVVKRSQSFSKERTESPSASALVQPPANTEEGKTHSVNKFVDIPQLGVSDKE Sbjct: 1021 SGPSPFALAVVKRSQSFSKERTESPSASALVQPPANTEEGKTHSVNKFVDIPQLGVSDKE 1080 Query: 1081 NNSAHNEQNSQIPTPTDGPSFTVMRQSSLTFQSSDPEQMRQSLLTAIRSGEAAAKLKRVT 1140 NNSAHNEQNSQIPTPTDGPSFTVMRQSSLTFQSSDPEQMRQSLLTAIRSGEAAAKLKRVT Sbjct: 1081 NNSAHNEQNSQIPTPTDGPSFTVMRQSSLTFQSSDPEQMRQSLLTAIRSGEAAAKLKRVT 1140 Query: 1141 IPSNTISVNGRSRLSHSMSPDAQDGH 1166 IPSNTISVNGRSRLSHSMSPDAQDGH Sbjct: 1141 IPSNTISVNGRSRLSHSMSPDAQDGH 1166 >gi|31581524 cordon-bleu homolog [Homo sapiens] Length = 1261 Score = 232 bits (592), Expect = 1e-60 Identities = 300/1160 (25%), Positives = 481/1160 (41%), Gaps = 230/1160 (19%) Query: 1 MDGRTPRPQDAPARRKPKAKAPLPPAETKYTDVSSAADSVESTAF-----IMEQKENMID 55 MD P RK KA+AP PP + V S A ++ KE + Sbjct: 1 MDAPRASAAKPPTGRKMKARAPPPPGKAATLHVHSDQKPPHDGALGSQQNLVRMKEALRA 60 Query: 56 KDVELSVVLPGDIIKSTTVHGSKPMMDLLIFLCAQYHLNPSSYTIDLLSAE-QNHIKFKP 114 ++++VVLP + K + ++GS MMDLL+ LC Q HLNPS + +++ S+E Q + FKP Sbjct: 61 STMDVTVVLPSGLEKRSVLNGSHAMMDLLVELCLQNHLNPSHHALEIRSSETQQPLSFKP 120 Query: 115 NTPIGMLEVEKVILKPKMLDKK-KP-TPIIPEKTVRVVINFKKTQKTIVRVSPHASLQEL 172 NT IG L V V LK K+ ++K KP P +PEK+VR+V+N+ +TQK +VRVSP LQ + Sbjct: 121 NTLIGTLNVHTVFLKEKVPEEKVKPGPPKVPEKSVRLVVNYLRTQKAVVRVSPEVPLQNI 180 Query: 173 APIICSKCEFDPLHTLLLKDYQSQEPLDLTKSLNDLGLRELYAMDVNRESCQISQNLDIM 232 P+IC+KCE P H +LL+D + E L+L+KSLN+LG++ELYA D RE+ + S + Sbjct: 181 LPVICAKCEVSPEHVVLLRDNIAGEELELSKSLNELGIKELYAWDNRRETFRKSSLGNDE 240 Query: 233 KEKENKGFFSFFQRSKKKRDQ-TASAPATPLVNKHRPTFTRSNTISKPYISNTLPSDAPK 291 +KE K F FF+ +K+ + + P +P + H + T ++S IS K Sbjct: 241 TDKEKKKFLGFFKVNKRSNSKGCLTTPNSP--SMHSRSLTLGPSLSLGSISGVSVKSEMK 298 Query: 292 KRRAPLPPMPASQSVPQDLAHIQERPASCIVKSMSVDETDKSPCEAGRVRAGSLQLSSMS 351 KRRA PP P S QD A + +V GS Sbjct: 299 KRRA--PPPPGSGPPVQDKA-------------------------SEKVSLGS------- 324 Query: 352 AGNSSLRRTKRKAPSPPSKIPPHQS----------DENSRVTALQPVDGVPPDSASEAN- 400 L++ KR+AP+PP PP S +EN + T + +P S S + Sbjct: 325 --QIDLQKKKRRAPAPPPPQPPPPSPLIPNRTEDKEENRKSTMV----SLPLGSGSHCSP 378 Query: 401 --SPEELS-SPETFHPGLSSQEQCTAPKLMEETSVFECPGTPEAAITSLTSGISS-DYSL 456 +P+ LS + ET G + T E++ V P + I SL S S Y Sbjct: 379 DGAPQVLSEAEETVSVGSCFASEDTT----EDSGVMSSP----SDIVSLDSQQDSMKYKD 430 Query: 457 EEIDEKEELSEVPKVEAENISPKSQDI--------PFVSTDIINTLKNDPDSALGNGSGE 508 + ++E+ S+ ++ P+ + + T+ T ND + L +GE Sbjct: 431 KWATDQEDCSDQDLAGTPDLGPQKSPLWEKNGSENSHLRTEKAVTASNDEEDLL--IAGE 488 Query: 509 FSQ------NSMEEKQETKSTDGQEPHSVVYDTSNGKKVVDSIRNLKSLGPNQENVQNEI 562 F + +EE +++ TD S ++ SN ++ P+ + + Sbjct: 489 FRKTLAELDEDLEEMEDSYETDTSSLTSSIHGASNHCP-------QDAMIPHGDTDAIPV 541 Query: 563 IVYPENTEDNMKNGVKKTEINVEGVAKNNNIDMEVERPSNSEAHETDTAISYKENHLA-- 620 E ++D + +G+ N G + + + + +A + +E A Sbjct: 542 TFIGEVSDDPVDSGLFSNRNNNAGSFDSEGVASRRDSLAPLQAEHSQPHEKAREEVPALH 601 Query: 621 -ASSVPDQKLNQPSAEKTKDA-AIQTTPSCNSFDGKHQDHNLSDSKVEECVQTSNNNIST 678 AS + + + +KD ++T P SF NL ++KV++ V Sbjct: 602 PASHDVGKGIRVALSNISKDGNLMETAPRVTSFASNLHTDNL-NAKVKDKV--------- 651 Query: 679 QHSCLSSQDSVNTSREFRSQGTLIIHSEDPLTVKDPICAHGNDDLLPPVDRIDKNSTASY 738 + C + R+Q T ++S+ PV+ D N + Sbjct: 652 -YGCADGE---------RTQATERVNSQ-------------------PVNEKDSNDKNAA 682 Query: 739 LKNYPLYRQDYNPKPKPSNEITREYIPKIGMTTYKIVPPKSLE--ISKDWQSETIEYKDD 796 L +++ NP + Y K G+TTYKI+PPKS +D T K D Sbjct: 683 LAPTSWHQRGQNP--------GKSYRLKHGLTTYKIIPPKSEMRCYDRDVSLSTGAIKID 734 Query: 797 Q-----DMHALGKKHTHENVKETAIQTEDSAISESPEEPLPNLKP--KPNLRTEH----- 844 + HA G + I + S++ E+ +P+ ++ + N +H Sbjct: 735 ELGNLVSPHATGIR----------IISLSSSVPEAESQPIGKVREFWRCNSVEKHLGRPS 784 Query: 845 ----------QVPSSVSSPDDAMVS---PLKPAPKMTRDTGTAPFAPNLEEINNILESKF 891 VP+ +P+ + + P+ P K G P + + Sbjct: 785 ESSARGPPSTPVPTQTQNPESRLQADPKPISPQQKSAHHEGRNPLGEGRNQPPTMGMGHV 844 Query: 892 KSRASNAQAKPSSFFLQMQKRVSGHYVTSAAAKSVHAAPNPAPKELTNKEAER------D 945 + A++ FL+ Q+R S YV SA AK + A A + AE+ Sbjct: 845 RVPAAHT---TEVTFLKPQRRTSSQYVASAIAKRIGAPKVHADVVRPHGYAEKGYAGKAP 901 Query: 946 MLPSPEQTL-SPLSKMPHSVPQ--------PLVEKTDDDVIGQAPAEASPPPIAPKPVTI 996 +L +P T+ + PHS Q P V T + G+ A +PP V Sbjct: 902 VLAAPPVTVKDDRTSSPHSETQGWKDGAQWPCV--TPPNNHGEDLAVGAPP---RGEVIG 956 Query: 997 PASQVSTQNLKTLKTFGAPRPYSSSGPSPFAL--------AVVKRSQSFS-KERTESPSA 1047 P ++STQ+ RP + S F+L V +S FS K+ T S A Sbjct: 957 PHRKLSTQD----------RPAAIHRSSCFSLVQSSQRDRVSVGQSCGFSGKQSTSSQEA 1006 Query: 1048 SALVQP---PANTEEGKTHS 1064 S+ +P P T+ H+ Sbjct: 1007 SSASEPRRAPDGTDPPPPHT 1026 >gi|148727245 thioredoxin domain-containing 2 isoform 1 [Homo sapiens] Length = 486 Score = 57.0 bits (136), Expect = 1e-07 Identities = 78/278 (28%), Positives = 106/278 (38%), Gaps = 44/278 (15%) Query: 288 DAPKKRRAPLPP----MPASQSVP--QDLAHIQERPASCIVKSMSVDETD--KSPCEAGR 339 D PK + P +P S + P L +I A VK E+D KSP E + Sbjct: 126 DLPKSSEEAIQPKEGDIPKSSAKPIQPKLGNI----AKTSVKPSQPKESDIPKSPEETIQ 181 Query: 340 VRAGSLQLSSMSA-----GNSSLRRTKRKAP-------SPPSKIPPHQSD-ENSRVTALQ 386 + G + SS GN K P SP I P + D S A+Q Sbjct: 182 PKEGDIPKSSAKPIQPKLGNIPKASVKPSQPKEGDISKSPEEAIQPKEGDLPKSLEEAIQ 241 Query: 387 PVDGVPPDSASEANSPEELSSPETFHPGLSSQEQCTAPKLMEET---SVFECPGTPEAAI 443 P +G P S EA P+E P++ + +E PK EET + P +PE AI Sbjct: 242 PKEGDIPKSPEEAIQPKEGDIPKSLEEAIQPKEG-DIPKSPEETIQPKKGDIPKSPEEAI 300 Query: 444 TSLTSGISSDYSLEEIDEKEELSEVPKVEAENISPKSQDIPFVSTDIINTLKNDPDSALG 503 I + I KE ++PK E I PK DIP + I ++D Sbjct: 301 QPKEGDIPKSPK-QAIQPKE--GDIPKSLEEAIPPKEIDIPKSPEETIQPKEDD------ 351 Query: 504 NGSGEFSQNSMEEKQETKSTDGQEPHSVVYDTSNGKKV 541 S S+EE +K D +P + G KV Sbjct: 352 ------SPKSLEEATPSKEGDILKPEEETMEFPEGDKV 383 Score = 37.4 bits (85), Expect = 0.084 Identities = 76/363 (20%), Positives = 138/363 (38%), Gaps = 34/363 (9%) Query: 457 EEIDEKEELSEVPKVEAENISPKSQDIPFVSTDIINTLKNDPDSALGNGSGEFSQNSMEE 516 EE D +E ++PK A PK D P S + I + D A E + S +E Sbjct: 11 EESDASQEGDDLPKSSANTSHPKQDDSPKSSEETIQPKEGDIPKA-----PEETIQSKKE 65 Query: 517 KQETKSTDGQEPHSVVYDTSNGKKVVDSIRNL--KSLGPNQENVQNEIIVYPENTEDNMK 574 S +P S+ K + + N+ S+ P+Q + +I PE T + K Sbjct: 66 DLPKSSEKAIQPKESNIPKSSAKPIQPKLGNIPKASVKPSQPK-EGDIPKAPEETIQSKK 124 Query: 575 NGVKKTEINVEGV-AKNNNIDMEVERPSNSEAHETDTAISYKENHLAASSVP--DQKLNQ 631 + K+ + E + K +I +P + S K + S +P ++ Q Sbjct: 125 EDLPKS--SEEAIQPKEGDIPKSSAKPIQPKLGNI-AKTSVKPSQPKESDIPKSPEETIQ 181 Query: 632 P-------SAEKTKDAAIQTTPSCNSFDGKHQDHNLSDSKVEECVQTSNNNI--STQHSC 682 P S+ K + P + + ++ ++S S EE +Q ++ S + + Sbjct: 182 PKEGDIPKSSAKPIQPKLGNIPKASVKPSQPKEGDISKSP-EEAIQPKEGDLPKSLEEAI 240 Query: 683 LSSQDSVNTSREFRSQ---GTLIIHSEDPLTVKDPICAHGNDDLLPPVDRIDKNSTASYL 739 + + S E Q G + E+ + K+ ++ + P S + Sbjct: 241 QPKEGDIPKSPEEAIQPKEGDIPKSLEEAIQPKEGDIPKSPEETIQPKKGDIPKSPEEAI 300 Query: 740 KNYPLYRQDYNPKPKPSNEITREYIPKIGMTTYKIVPPKSLEISKDWQSETIEYKDDQDM 799 + D PK + + IPK + + +PPK ++I K ETI+ K+D Sbjct: 301 QP---KEGDIPKSPKQAIQPKEGDIPK---SLEEAIPPKEIDIPKS-PEETIQPKEDDSP 353 Query: 800 HAL 802 +L Sbjct: 354 KSL 356 Score = 35.0 bits (79), Expect = 0.42 Identities = 42/167 (25%), Positives = 70/167 (41%), Gaps = 16/167 (9%) Query: 267 RPTFTRSNTISKPYISNTLPSDAPKKRRAPLPPMPASQSVPQDLAHIQERPASCIVKSMS 326 +P+ + ISK P +A + + LP P++ I + P I Sbjct: 208 KPSQPKEGDISKS------PEEAIQPKEGDLPKSLEEAIQPKE-GDIPKSPEEAIQPKEG 260 Query: 327 VDETDKSPCEAGRVRAGSLQLSSMSAGNSSLRRTKRKAP-SPPSKIPPHQSD-ENSRVTA 384 + KS EA + + G + S +++ K P SP I P + D S A Sbjct: 261 --DIPKSLEEAIQPKEGDIPKSP----EETIQPKKGDIPKSPEEAIQPKEGDIPKSPKQA 314 Query: 385 LQPVDGVPPDSASEANSPEELSSPETFHPGLSSQEQCTAPKLMEETS 431 +QP +G P S EA P+E+ P++ + +E +PK +EE + Sbjct: 315 IQPKEGDIPKSLEEAIPPKEIDIPKSPEETIQPKED-DSPKSLEEAT 360 >gi|148727319 thioredoxin domain-containing 2 isoform 2 [Homo sapiens] Length = 553 Score = 57.0 bits (136), Expect = 1e-07 Identities = 78/278 (28%), Positives = 106/278 (38%), Gaps = 44/278 (15%) Query: 288 DAPKKRRAPLPP----MPASQSVP--QDLAHIQERPASCIVKSMSVDETD--KSPCEAGR 339 D PK + P +P S + P L +I A VK E+D KSP E + Sbjct: 193 DLPKSSEEAIQPKEGDIPKSSAKPIQPKLGNI----AKTSVKPSQPKESDIPKSPEETIQ 248 Query: 340 VRAGSLQLSSMSA-----GNSSLRRTKRKAP-------SPPSKIPPHQSD-ENSRVTALQ 386 + G + SS GN K P SP I P + D S A+Q Sbjct: 249 PKEGDIPKSSAKPIQPKLGNIPKASVKPSQPKEGDISKSPEEAIQPKEGDLPKSLEEAIQ 308 Query: 387 PVDGVPPDSASEANSPEELSSPETFHPGLSSQEQCTAPKLMEET---SVFECPGTPEAAI 443 P +G P S EA P+E P++ + +E PK EET + P +PE AI Sbjct: 309 PKEGDIPKSPEEAIQPKEGDIPKSLEEAIQPKEG-DIPKSPEETIQPKKGDIPKSPEEAI 367 Query: 444 TSLTSGISSDYSLEEIDEKEELSEVPKVEAENISPKSQDIPFVSTDIINTLKNDPDSALG 503 I + I KE ++PK E I PK DIP + I ++D Sbjct: 368 QPKEGDIPKSPK-QAIQPKE--GDIPKSLEEAIPPKEIDIPKSPEETIQPKEDD------ 418 Query: 504 NGSGEFSQNSMEEKQETKSTDGQEPHSVVYDTSNGKKV 541 S S+EE +K D +P + G KV Sbjct: 419 ------SPKSLEEATPSKEGDILKPEEETMEFPEGDKV 450 Score = 37.4 bits (85), Expect = 0.084 Identities = 76/363 (20%), Positives = 138/363 (38%), Gaps = 34/363 (9%) Query: 457 EEIDEKEELSEVPKVEAENISPKSQDIPFVSTDIINTLKNDPDSALGNGSGEFSQNSMEE 516 EE D +E ++PK A PK D P S + I + D A E + S +E Sbjct: 78 EESDASQEGDDLPKSSANTSHPKQDDSPKSSEETIQPKEGDIPKA-----PEETIQSKKE 132 Query: 517 KQETKSTDGQEPHSVVYDTSNGKKVVDSIRNL--KSLGPNQENVQNEIIVYPENTEDNMK 574 S +P S+ K + + N+ S+ P+Q + +I PE T + K Sbjct: 133 DLPKSSEKAIQPKESNIPKSSAKPIQPKLGNIPKASVKPSQPK-EGDIPKAPEETIQSKK 191 Query: 575 NGVKKTEINVEGV-AKNNNIDMEVERPSNSEAHETDTAISYKENHLAASSVP--DQKLNQ 631 + K+ + E + K +I +P + S K + S +P ++ Q Sbjct: 192 EDLPKS--SEEAIQPKEGDIPKSSAKPIQPKLGNI-AKTSVKPSQPKESDIPKSPEETIQ 248 Query: 632 P-------SAEKTKDAAIQTTPSCNSFDGKHQDHNLSDSKVEECVQTSNNNI--STQHSC 682 P S+ K + P + + ++ ++S S EE +Q ++ S + + Sbjct: 249 PKEGDIPKSSAKPIQPKLGNIPKASVKPSQPKEGDISKSP-EEAIQPKEGDLPKSLEEAI 307 Query: 683 LSSQDSVNTSREFRSQ---GTLIIHSEDPLTVKDPICAHGNDDLLPPVDRIDKNSTASYL 739 + + S E Q G + E+ + K+ ++ + P S + Sbjct: 308 QPKEGDIPKSPEEAIQPKEGDIPKSLEEAIQPKEGDIPKSPEETIQPKKGDIPKSPEEAI 367 Query: 740 KNYPLYRQDYNPKPKPSNEITREYIPKIGMTTYKIVPPKSLEISKDWQSETIEYKDDQDM 799 + D PK + + IPK + + +PPK ++I K ETI+ K+D Sbjct: 368 QP---KEGDIPKSPKQAIQPKEGDIPK---SLEEAIPPKEIDIPKS-PEETIQPKEDDSP 420 Query: 800 HAL 802 +L Sbjct: 421 KSL 423 Score = 35.0 bits (79), Expect = 0.42 Identities = 42/167 (25%), Positives = 70/167 (41%), Gaps = 16/167 (9%) Query: 267 RPTFTRSNTISKPYISNTLPSDAPKKRRAPLPPMPASQSVPQDLAHIQERPASCIVKSMS 326 +P+ + ISK P +A + + LP P++ I + P I Sbjct: 275 KPSQPKEGDISKS------PEEAIQPKEGDLPKSLEEAIQPKE-GDIPKSPEEAIQPKEG 327 Query: 327 VDETDKSPCEAGRVRAGSLQLSSMSAGNSSLRRTKRKAP-SPPSKIPPHQSD-ENSRVTA 384 + KS EA + + G + S +++ K P SP I P + D S A Sbjct: 328 --DIPKSLEEAIQPKEGDIPKSP----EETIQPKKGDIPKSPEEAIQPKEGDIPKSPKQA 381 Query: 385 LQPVDGVPPDSASEANSPEELSSPETFHPGLSSQEQCTAPKLMEETS 431 +QP +G P S EA P+E+ P++ + +E +PK +EE + Sbjct: 382 IQPKEGDIPKSLEEAIPPKEIDIPKSPEETIQPKED-DSPKSLEEAT 427 >gi|42516570 thioredoxin domain-containing 2 isoform 1 [Homo sapiens] Length = 486 Score = 57.0 bits (136), Expect = 1e-07 Identities = 78/278 (28%), Positives = 106/278 (38%), Gaps = 44/278 (15%) Query: 288 DAPKKRRAPLPP----MPASQSVP--QDLAHIQERPASCIVKSMSVDETD--KSPCEAGR 339 D PK + P +P S + P L +I A VK E+D KSP E + Sbjct: 126 DLPKSSEEAIQPKEGDIPKSSAKPIQPKLGNI----AKTSVKPSQPKESDIPKSPEETIQ 181 Query: 340 VRAGSLQLSSMSA-----GNSSLRRTKRKAP-------SPPSKIPPHQSD-ENSRVTALQ 386 + G + SS GN K P SP I P + D S A+Q Sbjct: 182 PKEGDIPKSSAKPIQPKLGNIPKASVKPSQPKEGDISKSPEEAIQPKEGDLPKSLEEAIQ 241 Query: 387 PVDGVPPDSASEANSPEELSSPETFHPGLSSQEQCTAPKLMEET---SVFECPGTPEAAI 443 P +G P S EA P+E P++ + +E PK EET + P +PE AI Sbjct: 242 PKEGDIPKSPEEAIQPKEGDIPKSLEEAIQPKEG-DIPKSPEETIQPKKGDIPKSPEEAI 300 Query: 444 TSLTSGISSDYSLEEIDEKEELSEVPKVEAENISPKSQDIPFVSTDIINTLKNDPDSALG 503 I + I KE ++PK E I PK DIP + I ++D Sbjct: 301 QPKEGDIPKSPK-QAIQPKE--GDIPKSLEEAIPPKEIDIPKSPEETIQPKEDD------ 351 Query: 504 NGSGEFSQNSMEEKQETKSTDGQEPHSVVYDTSNGKKV 541 S S+EE +K D +P + G KV Sbjct: 352 ------SPKSLEEATPSKEGDILKPEEETMEFPEGDKV 383 Score = 37.4 bits (85), Expect = 0.084 Identities = 76/363 (20%), Positives = 138/363 (38%), Gaps = 34/363 (9%) Query: 457 EEIDEKEELSEVPKVEAENISPKSQDIPFVSTDIINTLKNDPDSALGNGSGEFSQNSMEE 516 EE D +E ++PK A PK D P S + I + D A E + S +E Sbjct: 11 EESDASQEGDDLPKSSANTSHPKQDDSPKSSEETIQPKEGDIPKA-----PEETIQSKKE 65 Query: 517 KQETKSTDGQEPHSVVYDTSNGKKVVDSIRNL--KSLGPNQENVQNEIIVYPENTEDNMK 574 S +P S+ K + + N+ S+ P+Q + +I PE T + K Sbjct: 66 DLPKSSEKAIQPKESNIPKSSAKPIQPKLGNIPKASVKPSQPK-EGDIPKAPEETIQSKK 124 Query: 575 NGVKKTEINVEGV-AKNNNIDMEVERPSNSEAHETDTAISYKENHLAASSVP--DQKLNQ 631 + K+ + E + K +I +P + S K + S +P ++ Q Sbjct: 125 EDLPKS--SEEAIQPKEGDIPKSSAKPIQPKLGNI-AKTSVKPSQPKESDIPKSPEETIQ 181 Query: 632 P-------SAEKTKDAAIQTTPSCNSFDGKHQDHNLSDSKVEECVQTSNNNI--STQHSC 682 P S+ K + P + + ++ ++S S EE +Q ++ S + + Sbjct: 182 PKEGDIPKSSAKPIQPKLGNIPKASVKPSQPKEGDISKSP-EEAIQPKEGDLPKSLEEAI 240 Query: 683 LSSQDSVNTSREFRSQ---GTLIIHSEDPLTVKDPICAHGNDDLLPPVDRIDKNSTASYL 739 + + S E Q G + E+ + K+ ++ + P S + Sbjct: 241 QPKEGDIPKSPEEAIQPKEGDIPKSLEEAIQPKEGDIPKSPEETIQPKKGDIPKSPEEAI 300 Query: 740 KNYPLYRQDYNPKPKPSNEITREYIPKIGMTTYKIVPPKSLEISKDWQSETIEYKDDQDM 799 + D PK + + IPK + + +PPK ++I K ETI+ K+D Sbjct: 301 QP---KEGDIPKSPKQAIQPKEGDIPK---SLEEAIPPKEIDIPKS-PEETIQPKEDDSP 353 Query: 800 HAL 802 +L Sbjct: 354 KSL 356 Score = 35.0 bits (79), Expect = 0.42 Identities = 42/167 (25%), Positives = 70/167 (41%), Gaps = 16/167 (9%) Query: 267 RPTFTRSNTISKPYISNTLPSDAPKKRRAPLPPMPASQSVPQDLAHIQERPASCIVKSMS 326 +P+ + ISK P +A + + LP P++ I + P I Sbjct: 208 KPSQPKEGDISKS------PEEAIQPKEGDLPKSLEEAIQPKE-GDIPKSPEEAIQPKEG 260 Query: 327 VDETDKSPCEAGRVRAGSLQLSSMSAGNSSLRRTKRKAP-SPPSKIPPHQSD-ENSRVTA 384 + KS EA + + G + S +++ K P SP I P + D S A Sbjct: 261 --DIPKSLEEAIQPKEGDIPKSP----EETIQPKKGDIPKSPEEAIQPKEGDIPKSPKQA 314 Query: 385 LQPVDGVPPDSASEANSPEELSSPETFHPGLSSQEQCTAPKLMEETS 431 +QP +G P S EA P+E+ P++ + +E +PK +EE + Sbjct: 315 IQPKEGDIPKSLEEAIPPKEIDIPKSPEETIQPKED-DSPKSLEEAT 360 >gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens] Length = 2752 Score = 56.6 bits (135), Expect = 1e-07 Identities = 162/832 (19%), Positives = 308/832 (37%), Gaps = 131/832 (15%) Query: 247 SKKKRDQTASAPATPLVNKHRPTFTRSNTISK---------PYISNTLPSDAPKKRRAPL 297 S ++R + S+ +P R T RS ++S P S++ S K + Sbjct: 924 SPRQRSHSGSSSPSPSRVTSRTTPRRSRSVSPCSNVESRLLPRYSHSGSSSPDTKVKPET 983 Query: 298 PPMPA-SQSV-PQDLAHIQERPASCIVKSMSVDETDKSPCEAGRVRAGSLQL-----SSM 350 PP + S S+ P Q P + S S +KS + GSL L SS Sbjct: 984 PPRQSHSGSISPYPKVKAQTPPGPSLSGSKSPCPQEKSKDSLVQSCPGSLSLCAGVKSST 1043 Query: 351 SAGNSSLRRTKRKAPSPPSKIPPHQSDENSRVTALQPVDGVPPDSASEANSPEELSSPET 410 G S + + P H+SD +S P S + SP S +T Sbjct: 1044 PPGESYFGVSSLQLKGQSQTSPDHRSDTSS-----------PEVRQSHSESPSLQSKSQT 1092 Query: 411 FHPGLSSQEQCTAPKLMEETSVFECPGTPEAAITSLTSGISSDYSLEEIDEKEELSEVPK 470 G S+ +L + + + G A+ L SG+S + S + D S P Sbjct: 1093 SPKGGRSRSSSPVTELASRSPIRQDRGEFSAS-PMLKSGMSPEQSRFQSDS----SSYPT 1147 Query: 471 VEAENISPKSQDIPFVSTD-IINTLKNDPDSALGNGSGEFSQNSMEEKQETKSTDGQEPH 529 V++ ++ +S+ S + + + D ++ +FS ++++ E+ Sbjct: 1148 VDSNSLLGQSRLETAESKEKMALPPQEDATASPPRQKDKFSPFPVQDRPESSL------- 1200 Query: 530 SVVYDTSNGKKVVDSIRNLKSLGPNQENVQNEIIVYPENTEDNMKNGVKKTEINVEGVAK 589 V DT R G + E + + + ++ + V+K+E + Sbjct: 1201 -VFKDTLRTPP-----RERSGAGSSPETKEQNSALPTSSQDEELMEVVEKSEEPAGQILS 1254 Query: 590 NNNIDMEVERPSNSEAHETDTAISYKENHLAASSVPDQKLNQPSAEKTKDAAIQTTPSCN 649 + + +++ SN E+ E A S DQ +Q S E A++ + Sbjct: 1255 HLSSELKEMSTSNFESSPE------VEERPAVSLTLDQSQSQASLE-----AVEVPSMAS 1303 Query: 650 SFDGKHQDHNLSDSKVEECVQTSNNNISTQHSCLSS----QDSVNTSREFRSQGTLIIHS 705 S+ G H S +H LS+ ++S + EFR+ G L Sbjct: 1304 SWGGPH--------------------FSPEHKELSNSPLRENSFGSPLEFRNSGPL---- 1339 Query: 706 EDPLTVKDPICAHGNDDLLPP-VDRIDKNSTASYLKNYPLYRQDYNPKPKPSNEITREYI 764 + + +DL P +++++ + + + Q S+E++ + + Sbjct: 1340 --GTEMNTGFSSEVKEDLNGPFLNQLETDPSLD------MKEQSTRSSGHSSSELSPDAV 1391 Query: 765 PKIGMTTYKIVP-------PKSLEISKDWQSETIEYKDDQDMHALGKKHTHENVKETAIQ 817 K GM++ + + P++ + + + E KD L + + + ++ Sbjct: 1392 EKAGMSSNQSISSPVLDAVPRTPSRERSSSASSPEMKD-----GLPRTPSRRSRSGSSPG 1446 Query: 818 TEDSAISESPEEPLPNLKPKPNLRTEHQVPSSVSSPDDAMVSPLKPAPKMTRDTGTAPFA 877 D + + S + P ++ + PS S D+ P K P+ R +P + Sbjct: 1447 LRDGSGTPSRHSLSGS---SPGMKDIPRTPSRGRSECDSSPEP-KALPQTPRPRSRSPSS 1502 Query: 878 PNLEEINNILESKFKSRASNAQAKPSSFFLQMQKRVSGHYVTSAAAKSVHAAPNPAPKEL 937 P E+NN + + R+ + + + + G S +++ + P+ +P+E Sbjct: 1503 P---ELNNKCLTPQRERSGSESSVDQK---TVARTPLGQRSRSGSSQELDVKPSASPQER 1556 Query: 938 TNKEAERDMLPSPEQTLSPLSKMPHSVPQPLVEKTDDDVIGQAPAEASPPPIAPKPVTIP 997 + ++ D S +T +PL + S P V+ + + + S P + KP P Sbjct: 1557 SESDSSPD---SKAKTRTPLRQRSRSGSSPEVD-SKSRLSPRRSRSGSSPEVKDKPRAAP 1612 Query: 998 ASQVSTQNLKTLKTFGAPRPYSSSGPSPFALAVVKRSQSFSKERTESPSASA 1049 +Q + + +P P P+P AL RS S SK R SP S+ Sbjct: 1613 RAQSGSDS--------SPEP---KAPAPRALPRRSRSGSSSKGRGPSPEGSS 1653 Score = 40.8 bits (94), Expect = 0.008 Identities = 69/372 (18%), Positives = 136/372 (36%), Gaps = 24/372 (6%) Query: 809 ENVKETAIQTEDSAISESPEEPLPNLKPKPNLRTEHQVPSSVSSPDDAMVSPLKPAPKMT 868 E +E A Q SE E N + P + V ++ P M Sbjct: 1243 EKSEEPAGQILSHLSSELKEMSTSNFESSPEVEERPAVSLTLDQSQSQASLEAVEVPSMA 1302 Query: 869 RDTGTAPFAPNLEEINN--ILESKFKSRASNAQAKP------SSFFLQMQKRVSGHYVTS 920 G F+P +E++N + E+ F S + P + F ++++ ++G ++ Sbjct: 1303 SSWGGPHFSPEHKELSNSPLRENSFGSPLEFRNSGPLGTEMNTGFSSEVKEDLNGPFLNQ 1362 Query: 921 AAAKSVHAAPNPAPKELTNKEAERDMLP-SPEQTLSPLSKMPHSVPQPLVEKTDDDVIGQ 979 + P+ KE + + + SP+ S+ P+++ + Sbjct: 1363 -----LETDPSLDMKEQSTRSSGHSSSELSPDAVEKAGMSSNQSISSPVLDAVPRTPSRE 1417 Query: 980 APAEASPPPIAPKPVTIPASQVSTQNLKTLKT-FGAPRPYSSSGPSPFALAVVKRSQSFS 1038 + AS P + P+ + + + L+ G P +S SG SP + + Sbjct: 1418 RSSSASSPEMKDGLPRTPSRRSRSGSSPGLRDGSGTPSRHSLSGSSPGMKDIPRTPSRGR 1477 Query: 1039 KERTESPSASALVQPP-ANTEEGKTHSVNKFVDIPQLGVSDKENNSAHNEQNSQIPTPTD 1097 E SP AL Q P + + +N PQ ++ + + +Q + TP Sbjct: 1478 SECDSSPEPKALPQTPRPRSRSPSSPELNNKCLTPQ---RERSGSESSVDQKTVARTPLG 1534 Query: 1098 GPSFTVMRQSSLTFQSSDPEQMRQSLLTAIRSGEAAAKLKRVTIPSNTISVNGRSRLS-- 1155 S + Q S+ P++ +S + + L++ + ++ V+ +SRLS Sbjct: 1535 QRSRSGSSQELDVKPSASPQERSESDSSPDSKAKTRTPLRQRSRSGSSPEVDSKSRLSPR 1594 Query: 1156 ---HSMSPDAQD 1164 SP+ +D Sbjct: 1595 RSRSGSSPEVKD 1606 Score = 32.3 bits (72), Expect = 2.7 Identities = 49/204 (24%), Positives = 77/204 (37%), Gaps = 17/204 (8%) Query: 869 RDTGTAPFAPNLEEINNILESKFKSRASNAQAKPSSFFLQMQKRVSGHYVTSAAAKSVHA 928 R G APF+ ++ S A +PSS + K T + + Sbjct: 303 RGEGDAPFSEP-----GTTSTQRPSSPETATKQPSSPYEDKDKDKKEKSATRPSPSPERS 357 Query: 929 APNPAPKELTNKEAERDMLPSPEQTLSPLSKMPHSVPQPL-------VEKTDDDVIGQAP 981 + P P T AER +PLS+ P + P K+ + + + Sbjct: 358 STGPEPPAPTPLLAERHGGSPQPLATTPLSQEPVNPPSEASPTRDRSPPKSPEKLPQSSS 417 Query: 982 AEASPPPIAPKPVTIPASQVSTQNLKTLKTFGAPRPYSSSGPSP-FALAVVKRSQSFSKE 1040 +E+SPP P V+ AS S ++ K G+ R SSS S + KR +S S Sbjct: 418 SESSPPSPQPTKVSRHASS-SPESPKPAPAPGSHREISSSPTSKNRSHGRAKRDKSHSHT 476 Query: 1041 RTESPSASALVQPPANTEEGKTHS 1064 + S + PA + G++ S Sbjct: 477 PSRRMGRS---RSPATAKRGRSRS 497 >gi|150170670 piccolo isoform 2 [Homo sapiens] Length = 4935 Score = 50.8 bits (120), Expect = 7e-06 Identities = 169/866 (19%), Positives = 294/866 (33%), Gaps = 135/866 (15%) Query: 341 RAGSLQLSSMSAGNSSLRRTKRKAPSPPSKIPPHQSDENSRVTALQPVDGVPPDSASEAN 400 R S + S +R + + +PPS + P + D P + +A Sbjct: 1800 RKSSSKKSKKDKDELRAQRRRERPKTPPSNLSPIE-------------DASPTEELRQAA 1846 Query: 401 SPEEL--SSPETFHPGLSSQEQ---CTAPKLMEETSVFECPG-------TPEAAITSLTS 448 EEL SS + P + S + + K++E V++ P T E +I Sbjct: 1847 EMEELHRSSCSEYSPSIESDPEGFEISPEKIIEVQKVYKLPTAVSLYSPTDEQSIMQKEG 1906 Query: 449 GISSDYSLEEIDEKEELSEVPKVEAENISPKSQDI---------PFVSTDIINTLKNDPD 499 + S EE+ E E + + K +A + + ++ + I +L D Sbjct: 1907 SQKALKSAEEMYE-EMMHKTHKYKAFPAANERDEVFEKEPLYGGMLIEDYIYESLVEDTY 1965 Query: 500 SALGNGS---------GEFSQNSMEEKQETKSTDGQEPHSVVYDTSNGKKVVDSIRNLKS 550 + +GS G Q E+K ++P + D +K + +L S Sbjct: 1966 NGSVDGSLLTRQEEENGFMQQKGREQKIRLSEQIYEDPMQKITDL---QKEFYELESLHS 2022 Query: 551 LGPNQENVQNEIIVYPENTEDNMKNGVKKTEINVEGVAKNNNIDMEVERPSNSEAHETDT 610 + P ++ V + I+ + ++ V TE ER + Sbjct: 2023 VVPQEDIVSSSFIIPESHEIVDLGTMVTSTE---------------EERKLLDADAAYEE 2067 Query: 611 AISYKENHLAASSVPDQK-LNQPSAEKTKDAAIQTTPSCNSFDGKHQDHNLSDSKVEECV 669 + ++ L S P Q + + E T D P + +L+DS + Sbjct: 2068 LMKRQQMQLTPGSSPTQAPIGEDMTESTMD--FDRMPDASLTSSVLSGASLTDSTSSATL 2125 Query: 670 QTSNNNISTQHSCLSSQDSVNT--SREFRSQGTLIIHSEDPLTVKDPICAHGNDDLLPPV 727 + I+ S +D T +RE + +I H LT +P + +PP Sbjct: 2126 SIPDVKITQHFSTEEIEDEYVTDYTREIQE---IIAHESLILTYSEP---SESATSVPPS 2179 Query: 728 DRIDKNSTASYLKNYPLYRQDYNPKPKPSNEITREYIPKIGMTTYKIVPPKSLEISKDWQ 787 D S+ S + D + + IT Y + M T K + + S + Sbjct: 2180 DTPSLTSSVS-----SVCTTDSSSPITTLDSITTVYTEPVDMIT-KFEDSEEISSSTYFP 2233 Query: 788 SETIEYKDD--QDMHALGKKHTHENVKETAIQTEDSAISESPEEPLPNLKPKPNLRTEHQ 845 I+Y ++ + + I D A S + ++ PKP E Sbjct: 2234 GSIIDYPEEISVSLDRTAPPDGRASADHIVISLSDMASSI-----IESVVPKP----EGP 2284 Query: 846 VPSSVSSPDDAMVSPLKPAPKMTRDTGTAPFAPNLEEINNILESKFKSRASNAQAK---- 901 V +VS+ D ++S P K ++TG LE + E + + S+ Sbjct: 2285 VADTVST--DLLISEKDPVKKAKKETGNGIILEVLEAYRDKKELEAERTKSSLSETVFDH 2342 Query: 902 -PSSFF-LQMQKRVSGHYVTSAAAKSVHAAPNPAPKELTNKEAERDMLPSPEQTLSPLSK 959 PSS L M++++S Y TS E +E LPS ++S L Sbjct: 2343 PPSSVIALPMKEQLSTTYFTSG--------------ETFGQEKPASQLPSGSPSVSSLP- 2387 Query: 960 MPHSVPQPLVEKTDDDVIGQAPAE------ASPPPIAPKPVTIPASQVSTQNLKTLKTFG 1013 + P+P + D+ Q P PPP P P +P + K Sbjct: 2388 ---AKPRPFFRSSSLDISAQPPPPPPPPPPPPPPPPPPPPPPLPPPTSPKPTILPKKKLT 2444 Query: 1014 APRPYSSSGPSPFALAVVKRSQSFSKERTESPSASALVQPPANTEEGKTHSVNKFVDIPQ 1073 P +++ P A+ ++ + PP + S F P+ Sbjct: 2445 VASPVTTATPLFDAVTTLETTAVLRSNGLPVTRICTTAPPPVPPKPSSIPSGLVFTHRPE 2504 Query: 1074 LGVSDKENNSAHNEQNSQIPTPTDGPSFTVMRQSSLTFQSSDPEQMRQSLLTAIRSGEAA 1133 + A Q+PT T P+ + + L+ SS M +L+T+ A Sbjct: 2505 ----PSKPPIAPKPVIPQLPTTTQKPTDIHPKPTGLSLTSS----MTLNLVTS-----AD 2551 Query: 1134 AKLKRVTIPSNTISVNGRSRLSHSMS 1159 KL T P + S R S S++ Sbjct: 2552 YKLPSPTSPLSPHSNKSSPRFSKSLT 2577 Score = 46.2 bits (108), Expect = 2e-04 Identities = 87/397 (21%), Positives = 139/397 (35%), Gaps = 61/397 (15%) Query: 765 PKIGMTTYKIVPPKSLEISKDWQSETIEYKDDQDMHALGK----KHTHENVKETAIQTED 820 P+ + T + ++ S +T KD L K K VK+ + Sbjct: 657 PQPKLKTAPVTTTSAVSKSSPQPQQTSPKKDAAPKQDLSKAPEPKKPPPLVKQPTLHGSP 716 Query: 821 SAISESPEEPLPNLKPKPNLRTEHQVPSSVSSPDDAMVSPLKPA-PKMTRDTGTAPFAPN 879 SA ++ P E KP P + PS S D A V+ KP PKM + T + + Sbjct: 717 SAKAKQPPEADSLSKPAPP-----KEPSVPSEQDKAPVADDKPKQPKMVKPTTDLVSSSS 771 Query: 880 LEEINNILESKFKSRASNA--------QAKPSSFFLQMQKRVSGHYVTS----AAAKSVH 927 +I SK +S+A AKPS F ++VS + A+ + Sbjct: 772 ATTKPDIPSSKVQSQAEEKTTPPLKTDSAKPSQSFPPTGEKVSPFDSKAIPRPASDSKII 831 Query: 928 AAPNPAPKELTNKEAER-DMLPSPEQTLSPLSKMPHSVPQPLVEKTDDDVIGQAPAEASP 986 + P P+ + K+ + P++ + +S P + P P T A Sbjct: 832 SHPGPSSESKGQKQVDPVQKKEEPKKAQTKMSPKPDAKPMPKGSPTPPGPRPTAGQTVPT 891 Query: 987 PPIAPKP--------------VTIPASQVST------------------QNLKTLKTFGA 1014 P +PKP P SQ +T Q + T G Sbjct: 892 PQQSPKPQEQSRRFSLNLGSITDAPKSQPTTPQETVTGKLFGFGASIFSQASNLISTAGQ 951 Query: 1015 PRPYSSSGPSPFALAVVKRSQSFSKERT-ESPSASALVQPPANTEEGKTHSVNKFVDIPQ 1073 P P+S SGP A +K++ + S+ T + P S PPA + K + Sbjct: 952 PGPHSQSGPG----APMKQAPAPSQPPTSQGPPKSTGQAPPAPAKSIPVKKETKAPAAEK 1007 Query: 1074 LGVSDKENNSAHNEQNSQIPTP-TDGPSFTVMRQSSL 1109 L ++ + + + P P D S T Q ++ Sbjct: 1008 LEPKAEQAPTVKRTETEKKPPPIKDSKSLTAEPQKAV 1044 Score = 32.0 bits (71), Expect = 3.5 Identities = 34/128 (26%), Positives = 49/128 (38%), Gaps = 16/128 (12%) Query: 930 PNPAPKELTNKEAERDMLPSPEQTLSPLSKMPHSVPQPLVEKTDDDVIGQAPAEASP--P 987 P ++ E+ + LPSP SK P + QP K G ++ P P Sbjct: 281 PQTKQADIVRGESVKPSLPSP-------SKPP--IQQPTPGKPPAQQPGHEKSQPGPAKP 331 Query: 988 PIAPKPVTIPASQVSTQNLKTLKTFGAPRPYSSSGPSPFALAVVKRSQSFS-KERTESPS 1046 P P +T P +Q ++ G +P + P A Q+ S K +E P Sbjct: 332 PAQPSGLTKPLAQQPGTVKPPVQPPGTTKPPAQ----PLGPAKPPAQQTGSEKPSSEQPG 387 Query: 1047 ASALVQPP 1054 AL QPP Sbjct: 388 PKALAQPP 395 >gi|150378539 piccolo isoform 1 [Homo sapiens] Length = 5142 Score = 50.8 bits (120), Expect = 7e-06 Identities = 169/866 (19%), Positives = 294/866 (33%), Gaps = 135/866 (15%) Query: 341 RAGSLQLSSMSAGNSSLRRTKRKAPSPPSKIPPHQSDENSRVTALQPVDGVPPDSASEAN 400 R S + S +R + + +PPS + P + D P + +A Sbjct: 1800 RKSSSKKSKKDKDELRAQRRRERPKTPPSNLSPIE-------------DASPTEELRQAA 1846 Query: 401 SPEEL--SSPETFHPGLSSQEQ---CTAPKLMEETSVFECPG-------TPEAAITSLTS 448 EEL SS + P + S + + K++E V++ P T E +I Sbjct: 1847 EMEELHRSSCSEYSPSIESDPEGFEISPEKIIEVQKVYKLPTAVSLYSPTDEQSIMQKEG 1906 Query: 449 GISSDYSLEEIDEKEELSEVPKVEAENISPKSQDI---------PFVSTDIINTLKNDPD 499 + S EE+ E E + + K +A + + ++ + I +L D Sbjct: 1907 SQKALKSAEEMYE-EMMHKTHKYKAFPAANERDEVFEKEPLYGGMLIEDYIYESLVEDTY 1965 Query: 500 SALGNGS---------GEFSQNSMEEKQETKSTDGQEPHSVVYDTSNGKKVVDSIRNLKS 550 + +GS G Q E+K ++P + D +K + +L S Sbjct: 1966 NGSVDGSLLTRQEEENGFMQQKGREQKIRLSEQIYEDPMQKITDL---QKEFYELESLHS 2022 Query: 551 LGPNQENVQNEIIVYPENTEDNMKNGVKKTEINVEGVAKNNNIDMEVERPSNSEAHETDT 610 + P ++ V + I+ + ++ V TE ER + Sbjct: 2023 VVPQEDIVSSSFIIPESHEIVDLGTMVTSTE---------------EERKLLDADAAYEE 2067 Query: 611 AISYKENHLAASSVPDQK-LNQPSAEKTKDAAIQTTPSCNSFDGKHQDHNLSDSKVEECV 669 + ++ L S P Q + + E T D P + +L+DS + Sbjct: 2068 LMKRQQMQLTPGSSPTQAPIGEDMTESTMD--FDRMPDASLTSSVLSGASLTDSTSSATL 2125 Query: 670 QTSNNNISTQHSCLSSQDSVNT--SREFRSQGTLIIHSEDPLTVKDPICAHGNDDLLPPV 727 + I+ S +D T +RE + +I H LT +P + +PP Sbjct: 2126 SIPDVKITQHFSTEEIEDEYVTDYTREIQE---IIAHESLILTYSEP---SESATSVPPS 2179 Query: 728 DRIDKNSTASYLKNYPLYRQDYNPKPKPSNEITREYIPKIGMTTYKIVPPKSLEISKDWQ 787 D S+ S + D + + IT Y + M T K + + S + Sbjct: 2180 DTPSLTSSVS-----SVCTTDSSSPITTLDSITTVYTEPVDMIT-KFEDSEEISSSTYFP 2233 Query: 788 SETIEYKDD--QDMHALGKKHTHENVKETAIQTEDSAISESPEEPLPNLKPKPNLRTEHQ 845 I+Y ++ + + I D A S + ++ PKP E Sbjct: 2234 GSIIDYPEEISVSLDRTAPPDGRASADHIVISLSDMASSI-----IESVVPKP----EGP 2284 Query: 846 VPSSVSSPDDAMVSPLKPAPKMTRDTGTAPFAPNLEEINNILESKFKSRASNAQAK---- 901 V +VS+ D ++S P K ++TG LE + E + + S+ Sbjct: 2285 VADTVST--DLLISEKDPVKKAKKETGNGIILEVLEAYRDKKELEAERTKSSLSETVFDH 2342 Query: 902 -PSSFF-LQMQKRVSGHYVTSAAAKSVHAAPNPAPKELTNKEAERDMLPSPEQTLSPLSK 959 PSS L M++++S Y TS E +E LPS ++S L Sbjct: 2343 PPSSVIALPMKEQLSTTYFTSG--------------ETFGQEKPASQLPSGSPSVSSLP- 2387 Query: 960 MPHSVPQPLVEKTDDDVIGQAPAE------ASPPPIAPKPVTIPASQVSTQNLKTLKTFG 1013 + P+P + D+ Q P PPP P P +P + K Sbjct: 2388 ---AKPRPFFRSSSLDISAQPPPPPPPPPPPPPPPPPPPPPPLPPPTSPKPTILPKKKLT 2444 Query: 1014 APRPYSSSGPSPFALAVVKRSQSFSKERTESPSASALVQPPANTEEGKTHSVNKFVDIPQ 1073 P +++ P A+ ++ + PP + S F P+ Sbjct: 2445 VASPVTTATPLFDAVTTLETTAVLRSNGLPVTRICTTAPPPVPPKPSSIPSGLVFTHRPE 2504 Query: 1074 LGVSDKENNSAHNEQNSQIPTPTDGPSFTVMRQSSLTFQSSDPEQMRQSLLTAIRSGEAA 1133 + A Q+PT T P+ + + L+ SS M +L+T+ A Sbjct: 2505 ----PSKPPIAPKPVIPQLPTTTQKPTDIHPKPTGLSLTSS----MTLNLVTS-----AD 2551 Query: 1134 AKLKRVTIPSNTISVNGRSRLSHSMS 1159 KL T P + S R S S++ Sbjct: 2552 YKLPSPTSPLSPHSNKSSPRFSKSLT 2577 Score = 46.2 bits (108), Expect = 2e-04 Identities = 87/397 (21%), Positives = 139/397 (35%), Gaps = 61/397 (15%) Query: 765 PKIGMTTYKIVPPKSLEISKDWQSETIEYKDDQDMHALGK----KHTHENVKETAIQTED 820 P+ + T + ++ S +T KD L K K VK+ + Sbjct: 657 PQPKLKTAPVTTTSAVSKSSPQPQQTSPKKDAAPKQDLSKAPEPKKPPPLVKQPTLHGSP 716 Query: 821 SAISESPEEPLPNLKPKPNLRTEHQVPSSVSSPDDAMVSPLKPA-PKMTRDTGTAPFAPN 879 SA ++ P E KP P + PS S D A V+ KP PKM + T + + Sbjct: 717 SAKAKQPPEADSLSKPAPP-----KEPSVPSEQDKAPVADDKPKQPKMVKPTTDLVSSSS 771 Query: 880 LEEINNILESKFKSRASNA--------QAKPSSFFLQMQKRVSGHYVTS----AAAKSVH 927 +I SK +S+A AKPS F ++VS + A+ + Sbjct: 772 ATTKPDIPSSKVQSQAEEKTTPPLKTDSAKPSQSFPPTGEKVSPFDSKAIPRPASDSKII 831 Query: 928 AAPNPAPKELTNKEAER-DMLPSPEQTLSPLSKMPHSVPQPLVEKTDDDVIGQAPAEASP 986 + P P+ + K+ + P++ + +S P + P P T A Sbjct: 832 SHPGPSSESKGQKQVDPVQKKEEPKKAQTKMSPKPDAKPMPKGSPTPPGPRPTAGQTVPT 891 Query: 987 PPIAPKP--------------VTIPASQVST------------------QNLKTLKTFGA 1014 P +PKP P SQ +T Q + T G Sbjct: 892 PQQSPKPQEQSRRFSLNLGSITDAPKSQPTTPQETVTGKLFGFGASIFSQASNLISTAGQ 951 Query: 1015 PRPYSSSGPSPFALAVVKRSQSFSKERT-ESPSASALVQPPANTEEGKTHSVNKFVDIPQ 1073 P P+S SGP A +K++ + S+ T + P S PPA + K + Sbjct: 952 PGPHSQSGPG----APMKQAPAPSQPPTSQGPPKSTGQAPPAPAKSIPVKKETKAPAAEK 1007 Query: 1074 LGVSDKENNSAHNEQNSQIPTP-TDGPSFTVMRQSSL 1109 L ++ + + + P P D S T Q ++ Sbjct: 1008 LEPKAEQAPTVKRTETEKKPPPIKDSKSLTAEPQKAV 1044 Score = 32.0 bits (71), Expect = 3.5 Identities = 34/128 (26%), Positives = 49/128 (38%), Gaps = 16/128 (12%) Query: 930 PNPAPKELTNKEAERDMLPSPEQTLSPLSKMPHSVPQPLVEKTDDDVIGQAPAEASP--P 987 P ++ E+ + LPSP SK P + QP K G ++ P P Sbjct: 281 PQTKQADIVRGESVKPSLPSP-------SKPP--IQQPTPGKPPAQQPGHEKSQPGPAKP 331 Query: 988 PIAPKPVTIPASQVSTQNLKTLKTFGAPRPYSSSGPSPFALAVVKRSQSFS-KERTESPS 1046 P P +T P +Q ++ G +P + P A Q+ S K +E P Sbjct: 332 PAQPSGLTKPLAQQPGTVKPPVQPPGTTKPPAQ----PLGPAKPPAQQTGSEKPSSEQPG 387 Query: 1047 ASALVQPP 1054 AL QPP Sbjct: 388 PKALAQPP 395 >gi|33620716 retinoblastoma-binding protein 6 isoform 2 [Homo sapiens] Length = 1758 Score = 49.7 bits (117), Expect = 2e-05 Identities = 73/353 (20%), Positives = 144/353 (40%), Gaps = 29/353 (8%) Query: 781 EISKDWQSETIEYKDDQDMHALGKKHTHENVKETAIQT----------EDSAISESPEEP 830 + SKD +SE + K+++ K +N E + E S++ S E Sbjct: 1079 DYSKDVKSEKLTTKEEKAKKPNEKNKPLDNKGEKRKRKTEEKGVDKDFESSSMKISKLEV 1138 Query: 831 LPNLKPKPNLRTEHQVPSSVSSPDDAMVSPLKPAPKMTRDTGTAPFAPNLEEINNILESK 890 +KP P + E +P+ +S PA K+ + T + E I+N E Sbjct: 1139 TEIVKPSPKRKMEPDTEKMDRTPEKDKISLSAPAKKIKLNRETGKKIGSTENISNTKEPS 1198 Query: 891 FKSRASNAQAKPSSFFLQMQKRVSGHYVTSAA----AKSVHAAPNPAPKELTNKEAERDM 946 K +++++ K +++++V+G +S+ + +P K + +R + Sbjct: 1199 EKLESTSSKVKQEKVKGKVRRKVTGTEGSSSTLVDYTSTSSTGGSPVRKSEEKTDTKRTV 1258 Query: 947 LPSPEQ----TLSPLSKMPHSVPQPLVEKTDDDVIGQAPAEASPPPIAPKPVTIPASQVS 1002 + + E+ +P + + P + DD + S PI+ V PAS + Sbjct: 1259 IKTMEEYNNDNTAPAEDVIIMIQVPQSKWDKDDFESEEEDVKSTQPIS--SVGKPASVI- 1315 Query: 1003 TQNLKTLKTFGAPRPYSSSGPSPFALAVVKRSQSFSKERTESPSASALVQPPANTEEGKT 1062 +N+ T + P S PS + K ++ S E + S+ + A++E+GKT Sbjct: 1316 -KNVSTKPSNIVKYPEKESEPSE---KIQKFTKDVSHEIIQHEVKSS--KNSASSEKGKT 1369 Query: 1063 HSVNKFVDIPQLGVSDKENNSAHNEQNSQIPTPTDGPSFTVMRQSSLTFQSSD 1115 ++ + + +K NS E+ S + + +F + QSS ++SD Sbjct: 1370 K--DRDYSVLEKENPEKRKNSTQPEKESNLDRLNEQGNFKSLSQSSKEARTSD 1420 Score = 32.3 bits (72), Expect = 2.7 Identities = 141/757 (18%), Positives = 267/757 (35%), Gaps = 98/757 (12%) Query: 188 LLLKDYQSQEPLDLTKSLNDLGLRELYAMDVNRESCQISQNLDIMKEKENKGFFSFFQRS 247 LL +S+EP + ++ D L+ + ++ + D + E+ F S ++ Sbjct: 919 LLETSRKSREPTGVEENKTD----SLFVLPSRDDATPVR---DEPMDAESITFKSVSEKD 971 Query: 248 KKKRDQTASAPATPLVNKHRPTFTRSNTISKPYISNTLPSDAPKKR--RAPLPPMPASQS 305 K++RD+ + ++ I KP D ++R R+ P A + Sbjct: 972 KRERDKPKAKGDKTKRKNDGSAVSKKENIVKPAKGPQEKVDGERERSPRSEPPIKKAKEE 1031 Query: 306 VP-----------QDLAHIQERPASCIVKSMSVDETDKSPCEAGRVRAGSLQLSSMSAGN 354 P Q I P KS + K P + +V+ + + + Sbjct: 1032 TPKTDNTKSSSSSQKDEKITGTPRKAHSKSAKEHQETK-PVKEEKVKKDYSK--DVKSEK 1088 Query: 355 SSLRRTKRKAPSPPSKIPPHQSDENSRVTALQPVDGVPPDSASEANSPEELSSPETFHPG 414 + + K K P+ +K ++ ++ R T + GV D S + +L E P Sbjct: 1089 LTTKEEKAKKPNEKNKPLDNKGEKRKRKTEEK---GVDKDFESSSMKISKLEVTEIVKP- 1144 Query: 415 LSSQEQCTAPKLMEETSVFECPGTPEAAITSLTSGISSDYSLEEIDEKEELSEVPKVEAE 474 +PK E + TPE SL++ E +K +E Sbjct: 1145 --------SPKRKMEPDTEKMDRTPEKDKISLSAPAKKIKLNRETGKKIGSTE----NIS 1192 Query: 475 NISPKSQDIPFVSTDIINTLKNDPDSALGNGSGEFSQNSMEEKQETKSTDGQEPHSVVYD 534 N S+ + S+ + G+ E S +++ + T ST G Sbjct: 1193 NTKEPSEKLESTSSKVKQEKVKGKVRRKVTGT-EGSSSTLVDYTSTSSTGGSPVRKSEEK 1251 Query: 535 TSNGKKVVDSIRNLKSLGPNQENVQNEIIV-------YPENTEDNMKNGVKKTEINVEGV 587 T + V+ ++ + N ++ II+ + ++ ++ + VK T+ + V Sbjct: 1252 TDTKRTVIKTMEEYNN--DNTAPAEDVIIMIQVPQSKWDKDDFESEEEDVKSTQ-PISSV 1308 Query: 588 AKNNNIDMEVE-RPSNSEAHETDTAISYKENHLAASSVPDQKLNQPSAEKTKDAAIQTTP 646 K ++ V +PSN + Y E S + S E + + Sbjct: 1309 GKPASVIKNVSTKPSN--------IVKYPEKESEPSEKIQKFTKDVSHEIIQHEVKSSKN 1360 Query: 647 SCNSFDGKHQDHNLSDSKVEECVQTSNNNISTQHSCLSSQDSVNTSREFRS--QGTLIIH 704 S +S GK +D + S + E + N STQ S+ D +N F+S Q + Sbjct: 1361 SASSEKGKTKDRDYSVLEKENPEKRKN---STQPEKESNLDRLNEQGNFKSLSQSSKEAR 1417 Query: 705 SEDPLTVKDPICAHGNDDLLPPVDRIDKNSTASYLKNYPLYRQDYNPKPKPSNEITREYI 764 + D D A N D P D+ T Y + R + N + + +R Sbjct: 1418 TSDK---HDSTRASSNKDFTPNRDKKTDYDTREYSSSKR--RDEKNELTRRKDSPSRN-- 1470 Query: 765 PKIGMTTYKIVPPKSLEISKDWQSETIEYKDDQDMHALGKKHTHENVKETAIQTEDS-AI 823 K + K P + ++ K ++ K + K H H+ +T E++ ++ Sbjct: 1471 -KDSASGQKNKPREERDLPKKGTGDS--KKSNSSPSRDRKPHDHKATYDTKRPNEETKSV 1527 Query: 824 SESP--EEPLPNLKPKPNLRTEHQVPSSVSSPDDAMV-----------SPLKPAPKM--- 867 ++P + L+ + N + + +P + V S +KP P++ Sbjct: 1528 DKNPCKDREKHVLEARNNKESSGNKLLYILNPPETQVEKEQITGQIDKSTVKPKPQLSHS 1587 Query: 868 -------TRDTGTAPFAPNLEEINNILESKFKSRASN 897 TR+T A F P+ E ++ K S+ Sbjct: 1588 SRLSSDLTRETDEAAFEPDYNESDSESNVSVKEEESS 1624 >gi|33620769 retinoblastoma-binding protein 6 isoform 1 [Homo sapiens] Length = 1792 Score = 49.7 bits (117), Expect = 2e-05 Identities = 73/353 (20%), Positives = 144/353 (40%), Gaps = 29/353 (8%) Query: 781 EISKDWQSETIEYKDDQDMHALGKKHTHENVKETAIQT----------EDSAISESPEEP 830 + SKD +SE + K+++ K +N E + E S++ S E Sbjct: 1113 DYSKDVKSEKLTTKEEKAKKPNEKNKPLDNKGEKRKRKTEEKGVDKDFESSSMKISKLEV 1172 Query: 831 LPNLKPKPNLRTEHQVPSSVSSPDDAMVSPLKPAPKMTRDTGTAPFAPNLEEINNILESK 890 +KP P + E +P+ +S PA K+ + T + E I+N E Sbjct: 1173 TEIVKPSPKRKMEPDTEKMDRTPEKDKISLSAPAKKIKLNRETGKKIGSTENISNTKEPS 1232 Query: 891 FKSRASNAQAKPSSFFLQMQKRVSGHYVTSAA----AKSVHAAPNPAPKELTNKEAERDM 946 K +++++ K +++++V+G +S+ + +P K + +R + Sbjct: 1233 EKLESTSSKVKQEKVKGKVRRKVTGTEGSSSTLVDYTSTSSTGGSPVRKSEEKTDTKRTV 1292 Query: 947 LPSPEQ----TLSPLSKMPHSVPQPLVEKTDDDVIGQAPAEASPPPIAPKPVTIPASQVS 1002 + + E+ +P + + P + DD + S PI+ V PAS + Sbjct: 1293 IKTMEEYNNDNTAPAEDVIIMIQVPQSKWDKDDFESEEEDVKSTQPIS--SVGKPASVI- 1349 Query: 1003 TQNLKTLKTFGAPRPYSSSGPSPFALAVVKRSQSFSKERTESPSASALVQPPANTEEGKT 1062 +N+ T + P S PS + K ++ S E + S+ + A++E+GKT Sbjct: 1350 -KNVSTKPSNIVKYPEKESEPSE---KIQKFTKDVSHEIIQHEVKSS--KNSASSEKGKT 1403 Query: 1063 HSVNKFVDIPQLGVSDKENNSAHNEQNSQIPTPTDGPSFTVMRQSSLTFQSSD 1115 ++ + + +K NS E+ S + + +F + QSS ++SD Sbjct: 1404 K--DRDYSVLEKENPEKRKNSTQPEKESNLDRLNEQGNFKSLSQSSKEARTSD 1454 Score = 32.3 bits (72), Expect = 2.7 Identities = 141/757 (18%), Positives = 267/757 (35%), Gaps = 98/757 (12%) Query: 188 LLLKDYQSQEPLDLTKSLNDLGLRELYAMDVNRESCQISQNLDIMKEKENKGFFSFFQRS 247 LL +S+EP + ++ D L+ + ++ + D + E+ F S ++ Sbjct: 953 LLETSRKSREPTGVEENKTD----SLFVLPSRDDATPVR---DEPMDAESITFKSVSEKD 1005 Query: 248 KKKRDQTASAPATPLVNKHRPTFTRSNTISKPYISNTLPSDAPKKR--RAPLPPMPASQS 305 K++RD+ + ++ I KP D ++R R+ P A + Sbjct: 1006 KRERDKPKAKGDKTKRKNDGSAVSKKENIVKPAKGPQEKVDGERERSPRSEPPIKKAKEE 1065 Query: 306 VP-----------QDLAHIQERPASCIVKSMSVDETDKSPCEAGRVRAGSLQLSSMSAGN 354 P Q I P KS + K P + +V+ + + + Sbjct: 1066 TPKTDNTKSSSSSQKDEKITGTPRKAHSKSAKEHQETK-PVKEEKVKKDYSK--DVKSEK 1122 Query: 355 SSLRRTKRKAPSPPSKIPPHQSDENSRVTALQPVDGVPPDSASEANSPEELSSPETFHPG 414 + + K K P+ +K ++ ++ R T + GV D S + +L E P Sbjct: 1123 LTTKEEKAKKPNEKNKPLDNKGEKRKRKTEEK---GVDKDFESSSMKISKLEVTEIVKP- 1178 Query: 415 LSSQEQCTAPKLMEETSVFECPGTPEAAITSLTSGISSDYSLEEIDEKEELSEVPKVEAE 474 +PK E + TPE SL++ E +K +E Sbjct: 1179 --------SPKRKMEPDTEKMDRTPEKDKISLSAPAKKIKLNRETGKKIGSTE----NIS 1226 Query: 475 NISPKSQDIPFVSTDIINTLKNDPDSALGNGSGEFSQNSMEEKQETKSTDGQEPHSVVYD 534 N S+ + S+ + G+ E S +++ + T ST G Sbjct: 1227 NTKEPSEKLESTSSKVKQEKVKGKVRRKVTGT-EGSSSTLVDYTSTSSTGGSPVRKSEEK 1285 Query: 535 TSNGKKVVDSIRNLKSLGPNQENVQNEIIV-------YPENTEDNMKNGVKKTEINVEGV 587 T + V+ ++ + N ++ II+ + ++ ++ + VK T+ + V Sbjct: 1286 TDTKRTVIKTMEEYNN--DNTAPAEDVIIMIQVPQSKWDKDDFESEEEDVKSTQ-PISSV 1342 Query: 588 AKNNNIDMEVE-RPSNSEAHETDTAISYKENHLAASSVPDQKLNQPSAEKTKDAAIQTTP 646 K ++ V +PSN + Y E S + S E + + Sbjct: 1343 GKPASVIKNVSTKPSN--------IVKYPEKESEPSEKIQKFTKDVSHEIIQHEVKSSKN 1394 Query: 647 SCNSFDGKHQDHNLSDSKVEECVQTSNNNISTQHSCLSSQDSVNTSREFRS--QGTLIIH 704 S +S GK +D + S + E + N STQ S+ D +N F+S Q + Sbjct: 1395 SASSEKGKTKDRDYSVLEKENPEKRKN---STQPEKESNLDRLNEQGNFKSLSQSSKEAR 1451 Query: 705 SEDPLTVKDPICAHGNDDLLPPVDRIDKNSTASYLKNYPLYRQDYNPKPKPSNEITREYI 764 + D D A N D P D+ T Y + R + N + + +R Sbjct: 1452 TSDK---HDSTRASSNKDFTPNRDKKTDYDTREYSSSKR--RDEKNELTRRKDSPSRN-- 1504 Query: 765 PKIGMTTYKIVPPKSLEISKDWQSETIEYKDDQDMHALGKKHTHENVKETAIQTEDS-AI 823 K + K P + ++ K ++ K + K H H+ +T E++ ++ Sbjct: 1505 -KDSASGQKNKPREERDLPKKGTGDS--KKSNSSPSRDRKPHDHKATYDTKRPNEETKSV 1561 Query: 824 SESP--EEPLPNLKPKPNLRTEHQVPSSVSSPDDAMV-----------SPLKPAPKM--- 867 ++P + L+ + N + + +P + V S +KP P++ Sbjct: 1562 DKNPCKDREKHVLEARNNKESSGNKLLYILNPPETQVEKEQITGQIDKSTVKPKPQLSHS 1621 Query: 868 -------TRDTGTAPFAPNLEEINNILESKFKSRASN 897 TR+T A F P+ E ++ K S+ Sbjct: 1622 SRLSSDLTRETDEAAFEPDYNESDSESNVSVKEEESS 1658 >gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens] Length = 1301 Score = 49.3 bits (116), Expect = 2e-05 Identities = 74/415 (17%), Positives = 151/415 (36%), Gaps = 22/415 (5%) Query: 324 SMSVDETDKSPCEAGRVRAGSLQLSSMSAGNSSLRRTKRKAPSPPSKIPPHQSDENSRVT 383 S S D +D S + S S S + S ++ S S S ++S Sbjct: 663 SNSSDSSDSSDSSDSSSSSDSSNSSDSSDSSDSSNSSESSDSSDSSDSDSSDSSDSSNSN 722 Query: 384 ALQPVDGVPPDSASEANSPEELSSPETFHPGLSSQEQCTAPKLMEETSVFECPGTPEAAI 443 + DS+ +NS + S ++ + SS + + +++ Sbjct: 723 SSDSDSSNSSDSSDSSNSSDSSDSSDSSNSSDSSDSS-------------DSSNSSDSSD 769 Query: 444 TSLTSGISSDYSLEEIDEKEELSEVPKVEAENISPKSQDIPFVSTDIINTLKNDPDSALG 503 +S +S S + + ++ S+ + S S D S + N DS+ Sbjct: 770 SSDSSDSSDSSNSSDSNDSSNSSDSSDSSNSSDSSNSSDSSDSSDSSDSDSSNSSDSSNS 829 Query: 504 NGSGEFSQNSMEEKQETKSTDGQEPHSVVY-DTSNGKKVVDSIRNLKSLGPNQENVQNEI 562 + S + S NS + + S+DG + S D+SN DS + S + + NE Sbjct: 830 SDSSD-SSNSSDSSDSSDSSDGSDSDSSNRSDSSNSSDSSDSSDSSNSSDSSDSSDSNE- 887 Query: 563 IVYPENTEDNMKNGVKKTEINVEGVAKNNNIDMEVERPSNSEAHETDTAISYKENHLAAS 622 N+ D+ + + + +++ D S+ ++ +D + S ++ + S Sbjct: 888 ---SSNSSDSSDSSNSSDSDSSDSSNSSDSSDSSNSSDSSESSNSSDNSNSSDSSNSSDS 944 Query: 623 SVPDQKLNQPSAEKTKDAAIQTTPSCNSFDGKHQDHNLSDSKVEECVQTSNNNISTQHSC 682 S N + + D++ + S ++ N SDS S+++ + +S Sbjct: 945 SDSSDSSNSSDSSNSSDSSNSSDSSDSNSSDSSDSSNSSDSSDSSDSSDSSDSSDSSNSS 1004 Query: 683 LSSQDSVNTSREFRSQGTLIIHSEDPLTVKDPICAHGNDDLLPPVDRIDKNSTAS 737 SS S ++ S + +S D D + + D D D + +++ Sbjct: 1005 DSSDSSDSSDSSNSSDSS---NSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSN 1056 Score = 43.5 bits (101), Expect = 0.001 Identities = 62/373 (16%), Positives = 140/373 (37%), Gaps = 9/373 (2%) Query: 323 KSMSVDETDKSPCEAGRVRAGS-LQLSSMSAGNSSLRRTKRKAPSPPSKIPPHQSDENSR 381 KSM D+ + S G A S +S S G++S + K S + D++ Sbjct: 458 KSMQGDDPNSSDESNGNDDANSESDNNSSSRGDASYNSDESKDNGNGSDSKGAEDDDSDS 517 Query: 382 VTALQPVDGVPPDSASEANSPEELSSPETFHPGLSSQEQCTAPKLMEETSVFECPGTPEA 441 + D DS N+ + + G S + + + + + Sbjct: 518 TS-----DTNNSDSNGNGNNGNDDNDKSDSGKGKSDSSDSDSSDSSNSSDSSDSSDSDSS 572 Query: 442 AITSLTSGISSDYSLEEIDEKEELSEVPKVEAENISPKSQ--DIPFVSTDIINTLKNDPD 499 S + SSD + + + ++ + S S D S ++ K++ D Sbjct: 573 DSNSSSDSDSSDSDSSDSSDSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSKSDSSKSESD 632 Query: 500 SALGNGSGEFSQNSMEEKQETKSTDGQEPHSVVYDTSNGKKVVDSIRNLKSLGPNQENVQ 559 S+ + + S ++ + + + S D+S+ DS + S + + Sbjct: 633 SSDSDSKSDSSDSNSSDSSDNSDSSDSSNSSNSSDSSDSSDSSDSSSSSDSSNSSDSSDS 692 Query: 560 NEIIVYPENTEDNMKNGVKKTEINVEGVAKNNNIDMEVERPSNSEAHETDTAISYKENHL 619 ++ E+++ + + ++ + + +++ D S+ ++ +D++ S ++ Sbjct: 693 SDSSNSSESSDSSDSSDSDSSDSSDSSNSNSSDSDSSNSSDSSDSSNSSDSSDSSDSSNS 752 Query: 620 AASSVPDQKLNQPSAEKTKDAAIQTTPSCNSFDGKHQDHNLSDSKVEECVQTSNNNISTQ 679 + SS N + + D++ ++ S NS D ++ S +SN++ S+ Sbjct: 753 SDSSDSSDSSNSSDSSDSSDSS-DSSDSSNSSDSNDSSNSSDSSDSSNSSDSSNSSDSSD 811 Query: 680 HSCLSSQDSVNTS 692 S S DS N+S Sbjct: 812 SSDSSDSDSSNSS 824 Score = 37.0 bits (84), Expect = 0.11 Identities = 60/352 (17%), Positives = 135/352 (38%), Gaps = 31/352 (8%) Query: 388 VDGVPPDSASEANSPEELSSPETFHPGLSSQEQCTAPKLMEETSVFECPGTPE--AAITS 445 + G P+S+ E+N ++ +S + + + + + + G + + TS Sbjct: 460 MQGDDPNSSDESNGNDDANSESDNNSSSRGDASYNSDESKDNGNGSDSKGAEDDDSDSTS 519 Query: 446 LTSGISSDYSLEEIDEKEELSEVPKVEAENISPKSQDIPFVSTDIINTLKNDPDSALGNG 505 T+ S+ + ++ + S+ K ++++ S D N DS+ + Sbjct: 520 DTNNSDSNGNGNNGNDDNDKSDSGKGKSDSSDSDSSDS-----------SNSSDSSDSSD 568 Query: 506 SGEFSQNSMEEKQETKSTDGQEPHSVVYDTSNGKKVVDSIRNLKSLGPNQENVQNEIIVY 565 S NS + + S S D+SN DS + S + Sbjct: 569 SDSSDSNSSSDSDSSDSDSSDSSDSDSSDSSNSSDSSDSSDSSDSSDSS----------- 617 Query: 566 PENTEDNMKNGVKKTEINVEGVAKNNNIDMEVERPSNSEAHETDTAISYKENHLAASSVP 625 ++ D+ + K + + +K+++ D S+ + +D++ S ++ + SS Sbjct: 618 --DSSDSKSDSSKSESDSSDSDSKSDSSDSN----SSDSSDNSDSSDSSNSSNSSDSSDS 671 Query: 626 DQKLNQPSAEKTKDAAIQTTPSCNSFDGKHQDHN-LSDSKVEECVQTSNNNISTQHSCLS 684 + S+ + +++ + S +S + D + SDS + +SN+N S S S Sbjct: 672 SDSSDSSSSSDSSNSSDSSDSSDSSNSSESSDSSDSSDSDSSDSSDSSNSNSSDSDSSNS 731 Query: 685 SQDSVNTSREFRSQGTLIIHSEDPLTVKDPICAHGNDDLLPPVDRIDKNSTA 736 S S +++ S + +S D D + + D D D ++++ Sbjct: 732 SDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSS 783 Score = 36.6 bits (83), Expect = 0.14 Identities = 57/353 (16%), Positives = 130/353 (36%), Gaps = 8/353 (2%) Query: 348 SSMSAGNSSLRRTKRKAPSPPSKIPPHQSDENSRVTALQPVDGVPPDSASEANSPEELSS 407 SS S+ +S+ + + S S NS ++ DS+ +NS + S Sbjct: 950 SSNSSDSSNSSDSSNSSDSSDSNSSDSSDSSNSSDSSDSSDSSDSSDSSDSSNSSDSSDS 1009 Query: 408 PETFHPGLSSQEQCTAPKLMEETSVFECPGTPEAAITSLTSGISSDYSLEEIDEKEELSE 467 ++ SS ++ S + + + + S S + D + Sbjct: 1010 SDSSDSSNSSDSSNSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDS 1069 Query: 468 VPKVEAENISPKSQDIPFVSTDIINTLKNDPDSALGNGSGEFSQNSMEEKQETKSTDGQE 527 ++ + S S+ + + + DS+ + S + S +S + + S+D + Sbjct: 1070 SDSSDSSDSSDSSESSDSSDSSNSSDSSDSSDSSDSSDSSD-SSDSSDSSDSSNSSDSSD 1128 Query: 528 --PHSVVYDTSNGKKVVDSIRNLKSLGPNQENVQNEIIVYPENTEDNMKNGVKKTEINVE 585 S D+SN DS + S + + ++ ++++ + + + + + Sbjct: 1129 SSDSSDSSDSSNSSDSSDSSESSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSD 1188 Query: 586 GVAKNNNIDMEVERPSNSEAHETDTAISYKENHLAASSVPDQKLNQPSAEKTKDAAIQTT 645 +++ D S+ + +D++ S ++ ++ S N+ S + ++ Sbjct: 1189 SSDSSDSSDSSDSSDSSDSSDSSDSSDS-SDSSDSSDSSDSSDSNESSDSSDSSDSSDSS 1247 Query: 646 PSCNSFDGKHQDHNLSDSKVEECVQT----SNNNISTQHSCLSSQDSVNTSRE 694 S +S D + SDS E Q+ NNN S S DS +++ + Sbjct: 1248 NSSDSSDSSDSSDSTSDSNDESDSQSKSGNGNNNGSDSDSDSEGSDSNHSTSD 1300 >gi|91982772 mucin 17 [Homo sapiens] Length = 4493 Score = 48.1 bits (113), Expect = 5e-05 Identities = 172/918 (18%), Positives = 317/918 (34%), Gaps = 104/918 (11%) Query: 255 ASAPATPLVNKHRPTFTRSNTISKPYISN--TLPSDAPKKRRAPLPPMPASQSV--PQDL 310 AS +T V+ P T + S P ++ ++P+ P + PL MP S+++ + Sbjct: 705 ASTLSTTPVDTSTPVTTSTEASSSPTTADGASMPTSTPSEGSTPLTSMPVSKTLLTSSEA 764 Query: 311 AHIQERPASCIVKSMSVDETDKSPCEAGRVRAGSLQLSSMSAGNSSLRRTKRKAPSPPSK 370 + + P + S + + ++ C S+ +S+ S G+ L S P Sbjct: 765 STLSTTP---LDTSTHITTSTEASCSPTTTEGTSMPISTPSEGSPLL-------TSIPVS 814 Query: 371 IPPHQSDENSRVTALQPVDGVPPDSASEANSPEELSSPETFHPGLSSQEQCTAPKLMEET 430 I P S E S ++ P DS S + E+SS T G S T Sbjct: 815 ITPVTSPEASTLST------TPVDSNSPVTTSTEVSSSPTPAEGTSM-----------PT 857 Query: 431 SVFECPGTPEAAITSLTSGISSDYSLEEIDEKEELSEVPKVEAENISPKSQDIPFVSTDI 490 S + TP ++ T+ +++ +S + + +P + S+ Sbjct: 858 STYSEGRTPLTSMPVSTTLVAT----------SAISTLSTTPVDTSTPVTNSTEARSSPT 907 Query: 491 INTLKNDPDSALGNGSGEFSQNSMEEKQETKSTDGQEPHSVVYDTSNGKKVVDSIRNLKS 550 + + P S G GS + + + S++ + + DTS V + S Sbjct: 908 TSEGTSMPTSTPGEGSTPLT-SMPDSTTPVVSSEARTLSATPVDTST---PVTTSTEATS 963 Query: 551 LGPNQENVQNEIIVYPENTEDNMKNGVKKTEINVEGVAKNNNIDMEVERPSNSEAHETDT 610 E P +T + T ++ VA + + ++ T T Sbjct: 964 SPTTAEGTS-----IPTSTPSEGTTPLTSTPVSHTLVANSEASTLSTTPVDSNTPLTTST 1018 Query: 611 AISYKENHLAASSVPDQKLNQPSAEKTKDAAIQTTPSCNSFDGKHQDHNLSDSKVEECVQ 670 S +S+P ++ S T+ + TT +S + LS + + Sbjct: 1019 EASSPPPTAEGTSMPTSTPSEGSTPLTR-MPVSTTMVASS-----ETSTLSTTPADTSTP 1072 Query: 671 TSNNNISTQHSCLSSQDSVNTSREFRSQGTLIIHSEDPLTVKDPICAHGNDDLLPPVDRI 730 + + ++ S + S+ TS S+G+ + S P++ + + + + PVD Sbjct: 1073 VTTYSQASSSSTTADGTSMPTST--YSEGSTPLTSV-PVSTRLVVSSEASTLSTTPVDTS 1129 Query: 731 DKNSTASYLKNYPLYRQDYNPKPKPSNEITREYIPKIGMTTYKIVPPKSLEISKDWQSET 790 +T++ + P + + P +E T P M P S + ++ T Sbjct: 1130 IPVTTSTEASSSPTTAEGTSIPTSPPSEGT---TPLASM-------PVSTTLVVSSEANT 1179 Query: 791 IEYKDDQDMHALGKKHTHENVKETAIQTEDSAISESPEEPLPNLKPKPNLRTEHQVPSSV 850 + + + TA T S + +P E L P T P + Sbjct: 1180 LSTTPVDSKTQVATSTEASSPPPTAEVT--SMPTSTPGERSTPLTSMPVRHT----PVAS 1233 Query: 851 SSPDDAMVSPLKPAPKMTRDTGTAPFAPNLEEINNILESKFKSRASNAQAKPSSFFLQMQ 910 S SP+ + +T T+ +P E ++ S ++ + P S L Sbjct: 1234 SEASTLSTSPVDTSTPVTTSAETSS-SPTTAEGTSLPTSTTSEGSTLLTSIPVSTTLVTS 1292 Query: 911 KRVSGHYVTSAAAKSVHAAPNPAPKELTNKEAERDMLPSPEQTLSPLSKMPHSVPQPLVE 970 S T K N T E + + +PL+ +P V LV Sbjct: 1293 PEASTLLTTPVDTKGPVVTSNEVSSSPTPAEGTSMPTSTYSEGRTPLTSIP--VNTTLVA 1350 Query: 971 KTDDDVIGQAPAEASPP----------PIAPKPVTIPASQVSTQNLKTLKTFGAPRPYSS 1020 + ++ P + S P P + ++P S S + P S Sbjct: 1351 SSAISILSTTPVDNSTPVTTSTEACSSPTTSEGTSMPNSNPSEGTTPLTSIPVSTTPVVS 1410 Query: 1021 SGPSPFALAVVKRSQ--SFSKERTESPSASALVQPPANT-EEGKTHSVNKFVDIPQLGVS 1077 S S + V S + S E T SP+ + + P +T EGKT P + Sbjct: 1411 SEASTLSATPVDTSTPGTTSAEATSSPTTAEGISIPTSTPSEGKT---------PLKSIP 1461 Query: 1078 DKENNSAHNEQNSQIPTPTDGPSFTVMRQSSLTFQSSDPEQMRQSLLTAIRSGEAAAKLK 1137 A++E ++ TP D S V + T SS P + + E + L Sbjct: 1462 VSNTPVANSEASTLSTTPVDSNSPVV----TSTAVSSSPTPAEGTSIAISTPSEGSTALT 1517 Query: 1138 RVTIPSNTISVNGRSRLS 1155 + + + T++ + + LS Sbjct: 1518 SIPVSTTTVASSEINSLS 1535 Score = 41.6 bits (96), Expect = 0.004 Identities = 64/325 (19%), Positives = 116/325 (35%), Gaps = 42/325 (12%) Query: 846 VPSSVSSPDDAMVSPLKPAPKMTRDTGTAPFA-PNLEEINNILESKFKSRASNAQAKPSS 904 +P + S ++P+ + +T T T P + P E ++L S ++ P S Sbjct: 344 MPVATSEMSTLSITPVDTSTLVT--TSTEPSSLPTTAEATSMLTSTLSEGSTPLTNMPVS 401 Query: 905 FFLQMQKRVSGHYVTSAAAKSVHAAPNPAPKELTNKEAERDMLPSPEQTLSPLSKMPHSV 964 L S +K+ + A T E +P + +PL+ MP S Sbjct: 402 TILVASSEASTTSTIPVDSKTFVTTASEASSSPTTAEDTSIATSTPSEGSTPLTSMPVST 461 Query: 965 PQPLVEKTDDDVIGQAPAEASPPPIAPKPVTIPASQVSTQNLKTLKTFGAPRPYSSSGPS 1024 V + S P+ K + S ++ + T + P S G + Sbjct: 462 ---------TPVASSEASNLSTTPVDSK-TQVTTSTEASSSPPTAEVNSMPTSTPSEGST 511 Query: 1025 PFALAVVKRSQSFSKERTESPSASALVQPPANTEEGKTHSVNKFVDIPQLGVSDKENNSA 1084 P S S S S AS L P +T T S + ++S+ Sbjct: 512 PLT------SMSVSTMPVASSEASTLSTTPVDTSTPVT-------------TSSEASSSS 552 Query: 1085 HNEQNSQIP--TPTDGP--------SFTVMRQSSLTFQSSDPEQMRQSLLTAIRSGEAAA 1134 + + IP TP++G S ++ S + S+ P + T+ + ++ Sbjct: 553 TTPEGTSIPTSTPSEGSTPLTNMPVSTRLVVSSEASTTSTTPADSNTFVTTSSEASSSST 612 Query: 1135 KLKRVTIPSNTISVNGRSRLSHSMS 1159 + ++P++T S G + S S+S Sbjct: 613 TAEGTSMPTSTYSERGTTITSMSVS 637 Score = 40.4 bits (93), Expect = 0.010 Identities = 169/930 (18%), Positives = 307/930 (33%), Gaps = 106/930 (11%) Query: 253 QTASAPATPLVNKHRPTFTRSNTISKPYISNTLPSDAPKKRRAPLPPMPASQS--VPQDL 310 + ++ ATP+ T + T S ++P+ P + PL +P S + + Sbjct: 3180 EDSTLSATPVDTSTPVTTSTEATSSTTAEGTSIPTSTPSEGMTPLTSVPVSNTPVASSEA 3239 Query: 311 AHIQERPASCIVKSMSVDETDKSPCEAGRVRAGSLQLSSMSAGNSSLR----RTKRKAPS 366 + + P + E SP A S+ S+ S G++ L T A S Sbjct: 3240 SILSTTPVDSNTPLTTSTEASSSPPTA---EGTSMPTSTPSEGSTPLTSMPVSTTTVASS 3296 Query: 367 PPSKIPPHQSDENSRVTALQPVDGVPPDSASEANSPEELSSPETFHPGLSSQEQCTAPKL 426 S + +D ++ VT PP + + S T L++ T P + Sbjct: 3297 ETSTLSTTPADTSTPVTTYSQASSSPPIADGTSMPTSTYSEGST---PLTNMSFSTTPVV 3353 Query: 427 MEETSVFECPGTPEAAITSLTSGISSDYSLEEIDEKEELSEVPKVEAENISPKS----QD 482 E S TP T +T+ + S + + P +E +P + Sbjct: 3354 SSEASTLST--TPVDTSTPVTTSTEASLSPTTAEGTSIPTSSP---SEGTTPLASMPVST 3408 Query: 483 IPFVSTDIINTLKNDP--DSALGNGSGEFSQNSM----EEKQETKSTDGQEPHSVV---- 532 P VS++ +NTL P + L S E S + + +++G P S++ Sbjct: 3409 TPVVSSE-VNTLSTTPVDSNTLVTTSTEASSSPTIAEGTSLPTSTTSEGSTPLSIMPLST 3467 Query: 533 -------YDTSNGKKVVDSIRNLKSLGPNQENVQNEIIVYPENTEDNMKNGVKKTEINVE 585 T + V S S N E+ P +T + ++ Sbjct: 3468 TPVASSEASTLSTTPVDTSTPVTTSSPTNSSPTTAEVTSMPTSTAGEGSTPLTNMPVSTT 3527 Query: 586 GVAKN-------NNIDMEVERPSNSEAHETDTAISYKENHLAASSVPDQKLNQPSAEKTK 638 VA + +D S+S+A + + ++ S L T Sbjct: 3528 PVASSEASTLSTTPVDSNTFVTSSSQASSSPATLQVTTMRMSTPSEGSSSLTTMLLSSTY 3587 Query: 639 DAAIQ-TTPSCNSFD-------GKHQDHNLSDSKVEECVQTSNNNISTQHSCLSSQDSVN 690 + + +TPS S D + + +V ++ + +ST + + + Sbjct: 3588 VTSSEASTPSTPSVDRSTPVTTSTQSNSTPTPPEVITLPMSTPSEVSTPLTIMPVSTTSV 3647 Query: 691 TSREFRSQGTLIIHSEDPLTV-----KDPICAHGNDDLLPPVDRIDKNSTASYLKNYPLY 745 T E + TL + + P+ P+ G P+ + ST PL Sbjct: 3648 TISEAGTASTLPVDTSTPVITSTQVSSSPVTPEGT---TMPIWTPSEGST-------PLT 3697 Query: 746 RQDYNPKPKPSNEITREYIPKIGMTTYKIVPPKSLEISKDWQSETIEYKDDQDMHALGKK 805 + S+E + P + +T +++ S S T+ ++ LG Sbjct: 3698 TMPVSTTRVTSSEGSTLSTPSVVTSTPVTTSTEAISSSATLDSTTMSVSMPMEISTLG-- 3755 Query: 806 HTHENVKETAIQTEDSAISESPEEPLPNLKPKPNLRTEHQVPSSVSSPDDAMVSPLKPAP 865 T I + ++ PE P+ +PS +S S +P Sbjct: 3756 --------TTILVSTTPVTRFPESSTPS------------IPSVYTSMSMTTASEGSSSP 3795 Query: 866 KMTRDTGTAPFAPNLEEINNILESKFKSRASNAQAKPSSFFLQMQKRVSGHYVTSAAAKS 925 T T P + E + +L + S S +S S +TS A S Sbjct: 3796 TTLEGTTTMPMSTTSER-STLLTTVLISPISVMSPSEASTLSTPPGDTSTPLLTSTKAGS 3854 Query: 926 VHAAPNPAPKELTN-KEAERDMLPSPEQTLSPLSKMPHSVPQPLVEKT---DDDVIGQAP 981 P E+T + + +P TL + +P S P + T D Sbjct: 3855 F-----SIPAEVTTIRISITSERSTPLTTLLVSTTLPTSFPGASIASTPPLDTSTTFTPS 3909 Query: 982 AEASPPPIAPKPVTIPASQVSTQNLKTLKTFGAPRPYSSSGPSPFAL---AVVKRSQSFS 1038 + + P P TI S ++ + F P +SS F AV + + Sbjct: 3910 TDTASTPTIPVATTISVSVITEGSTPGTTIFIPSTPVTSSTADVFPATTGAVSTPVITST 3969 Query: 1039 KERTESPSASALVQPPANTEEGKTHSVNKFVDIPQLGVSDKENNSAHNEQNSQIPTPTDG 1098 + T S S+S+ + T+E T ++ + + +S + + T Sbjct: 3970 ELNTPSTSSSSTTTSFSTTKEFTTPAMTTAAPLTYVTMSTAPSTPRTTSRGCTTSASTLS 4029 Query: 1099 PSFTVMRQSSLTFQSSDP--EQMRQSLLTA 1126 + T +S+T + P E R S +T+ Sbjct: 4030 ATSTPHTSTSVTTRPVTPSSESSRPSTITS 4059 Score = 40.0 bits (92), Expect = 0.013 Identities = 73/343 (21%), Positives = 122/343 (35%), Gaps = 54/343 (15%) Query: 830 PLPNLKPKPNLRTEHQVPSSVSSPDDAMVSPLKPA----PKMTRDTGTAPFAPNLEEINN 885 PLP+ + +L + + + +++ A SP P PK T G+ P + + Sbjct: 168 PLPSFEAYTSLTYKVDMSTPLTTSTQASSSPTTPESTTIPKSTNSEGSTP-------LTS 220 Query: 886 ILESKFKSRASNAQAKPSSFFLQMQKRVSGHYVTSAAAKSVHAAPNPAPKELTNKEAERD 945 + S K +S A L +S SA A S +P A + A Sbjct: 221 MPASTMKVASSEAIT-----LLTTPVEISTPVTISAQASS---SPTTAEGPSLSNSA--- 269 Query: 946 MLPSPEQTLSPLSKMPHSVPQPLVEKTDDDVIGQAPA----------EASPPPIAPKPVT 995 P +PL++MP SV LV ++ + PA EAS P + + Sbjct: 270 ----PSGGSTPLTRMPLSVM--LVVSSEASTLSTTPAATNIPVITSTEASSSPTTAEGTS 323 Query: 996 IPASQVSTQNLKTLKTFGAPRPYSSSGPSPFALAVVKRSQ--SFSKERTESP-SASALVQ 1052 IP S + + T + P ++S S ++ V S + S E + P +A A Sbjct: 324 IPTSTYTEGSTPLTSTPASTMPVATSEMSTLSITPVDTSTLVTTSTEPSSLPTTAEATSM 383 Query: 1053 PPANTEEGKTHSVNKFVDIPQLGVSDKENNSAHNEQNSQIPTPTDGPSFTVMRQSSLTFQ 1112 + EG T N V + S+ S P D +F + Sbjct: 384 LTSTLSEGSTPLTNMPVSTILVASSEASTTST---------IPVDSKTFVTTASEA---- 430 Query: 1113 SSDPEQMRQSLLTAIRSGEAAAKLKRVTIPSNTISVNGRSRLS 1155 SS P + + E + L + + + ++ + S LS Sbjct: 431 SSSPTTAEDTSIATSTPSEGSTPLTSMPVSTTPVASSEASNLS 473 Score = 39.7 bits (91), Expect = 0.017 Identities = 174/926 (18%), Positives = 298/926 (32%), Gaps = 144/926 (15%) Query: 255 ASAPATPLVNKHRPTFTRSNTISKPYISN--TLPSDAPKKRRAPLPPMPASQSVPQDLAH 312 AS +T V+ P T + S P + ++P+ P + PL MP Sbjct: 2768 ASTVSTTAVDTSIPVTTSTEASSSPTTAEVTSMPTSTPSETSTPLTSMP----------- 2816 Query: 313 IQERPASCIVKSMSVDETDKSPCEAGRVRAGSLQLSSMSAGNSSLRRTKRKAPSPPSK-- 370 V+ T + EAG LS+ S+ T KA S P+ Sbjct: 2817 --------------VNHTPVASSEAGT-------LSTTPVDTSTPVTTSTKASSSPTTAE 2855 Query: 371 ---IPPHQSDENSRVTALQPVDGVPPDSASEANSPEELSSPETFHPGLSSQEQCTAPKLM 427 +P + E S + PV P AS S + +T P +S E ++P Sbjct: 2856 GIVVPISTASEGSTLLTSIPVSTTPV--ASSEASTLSTTPVDTSIPVTTSTEGSSSPTTA 2913 Query: 428 EETSVFECP-GTPEAAITSLTSGISSDYSLEEIDEKEELSEVPKVEAENISPKSQDIPFV 486 E TS+ P TP T LTS + S + E LS P ++ ++ Sbjct: 2914 EGTSM---PISTPSEVSTPLTSILVSTVPVAG-SEASTLSTTPVDTRTPVTTSAEASSSP 2969 Query: 487 STDIINTLKNDPDSALGNGSGEFSQNSMEEKQETKSTDGQEPHSVVYDTSNGKKVVDSIR 546 +T ++ S ++M ST + P + + S Sbjct: 2970 TTAEGTSMPISTPGERRTPLTSMSVSTMPVASSEASTLSRTPADTSTPVTTSTEASSSPT 3029 Query: 547 NLKSLGPNQENVQNEIIVYPENTEDNMKNGVKKTEINVEGVAKNNNIDMEVERPSNSEAH 606 + G P +T + ++ VA + ++ Sbjct: 3030 TAEGTG------------IPISTPSEGSTPLTSIPVSTTPVAIPEASTLSTTPVDSNSPV 3077 Query: 607 ETDTAISYKENHLAASSVPDQKLNQPSAEKTKDAAIQTTPSCNSFDGKHQDHNLSDSKVE 666 T T +S +S+P ++ S T + TTP +S LS + V+ Sbjct: 3078 VTSTEVSSSPTPAEGTSMPISTYSEGSTPLT-GVPVSTTPVTSSAIS-----TLSTTPVD 3131 Query: 667 ECVQTSNNNISTQHSCLSSQDSVNTSREFRSQGTLIIHSEDPLT---VKDPICAHGNDDL 723 + + + HS ++ + + S+G+ PLT V + D Sbjct: 3132 TSTPVTTS--TEAHSSPTTSEGTSMPTSTPSEGST------PLTYMPVSTMLVVSSEDST 3183 Query: 724 LP--PVDRIDKNSTASYLKNYPLYRQDYNPKPKPSNEITREYIPKIGMTTYKIVPPKSLE 781 L PVD +T++ + P PS GMT VP + Sbjct: 3184 LSATPVDTSTPVTTSTEATSSTTAEGTSIPTSTPSE----------GMTPLTSVPVSNTP 3233 Query: 782 ISKDWQSETIEYKDDQDMHALGKKHTHENVKETAIQTEDSAISESPEEPLPNLKPKPNLR 841 ++ S D + T + T A S P ++ Sbjct: 3234 VASSEASILSTTPVDSN---------------TPLTTSTEASSSPPTAEGTSMPTS---- 3274 Query: 842 TEHQVPSSVSSPDDAM-VSPLKPAPKMTRDTGTAPFAPNLEEINNILESKFKSRASNAQA 900 PS S+P +M VS A T T P A + ++ ++ + Sbjct: 3275 ----TPSEGSTPLTSMPVSTTTVASSETSTLSTTP-ADTSTPVTTYSQASSSPPIADGTS 3329 Query: 901 KPSSFFLQMQKRVSGHYVTSAAAKSVHAAPNPAPKELTNKEAERDMLPSPEQTLSPLSKM 960 P+S + + ++ ++ S A+ T + + S E +LSP + Sbjct: 3330 MPTSTYSEGSTPLTNMSFSTTPVVSSEAST----LSTTPVDTSTPVTTSTEASLSPTTAE 3385 Query: 961 PHSVPQPLVEKTDDDVIGQAPAEASP----PPIAPKPVTIPASQVSTQNLKTLKTFGAPR 1016 S+P T G P + P P ++ + T+ + V + L T T + Sbjct: 3386 GTSIP------TSSPSEGTTPLASMPVSTTPVVSSEVNTLSTTPVDSNTLVTTSTEASSS 3439 Query: 1017 PYSSSGPSPFALAVVKRSQSFSKERTESPSASALVQPPANTEEGKTHSVNKFVDIPQLGV 1076 P + G S S + E + S L P + E T S + Sbjct: 3440 PTIAEGTS--------LPTSTTSEGSTPLSIMPLSTTPVASSEASTLSTTPVDTSTPVTT 3491 Query: 1077 SDKENNSAHNEQNSQIPTPTDGP----------SFTVMRQSSLTFQSSDPEQMRQSLLTA 1126 S N+S + + +PT T G S T + S + S+ P + ++ Sbjct: 3492 SSPTNSSPTTAEVTSMPTSTAGEGSTPLTNMPVSTTPVASSEASTLSTTPVDSNTFVTSS 3551 Query: 1127 IRSGEAAAKLKRVTIPSNTISVNGRS 1152 ++ + A L+ T+ +T S S Sbjct: 3552 SQASSSPATLQVTTMRMSTPSEGSSS 3577 Score = 35.8 bits (81), Expect = 0.24 Identities = 53/217 (24%), Positives = 85/217 (39%), Gaps = 34/217 (15%) Query: 255 ASAPATPLVNKHRPTFTRSNTISKPYISN--TLPSDAPKKRRAPLPPMPASQSVPQDLAH 312 AS +T V+ + P T + S P + ++ + RR PL MP S +V Sbjct: 2119 ASTLSTTPVDSNSPVITSTEVSSSPIPTEGTSMQTSTYSDRRTPLTSMPVSTTV------ 2172 Query: 313 IQERPASCIVKSMSVDETDKSPCEAGRVRAGSLQLSSMSAGNSSLRRTKRKAPSPPSKIP 372 AS + ++S D S A S + S G S T + +P + +P Sbjct: 2173 ----VASSAISTLSTTPVDTSTPVTNSTEARS--SPTTSEGTSMPTSTPSEGSTPFTSMP 2226 Query: 373 PHQSDENSRVTALQPVDGVPPDSASEANSPEELSSPETFHPGLSSQEQCTAPKLMEETSV 432 + PV V ++++ + +P + S+P T +S E ++P E TS+ Sbjct: 2227 ----------VSTMPV--VTSEASTLSATPVDTSTPVT-----TSTEATSSPTTAEGTSI 2269 Query: 433 FECPGTPEAAITSLTSGISSDYSLEEIDEKEELSEVP 469 T T LTS I ++L E LS P Sbjct: 2270 --PTSTLSEGTTPLTS-IPVSHTLVANSEVSTLSTTP 2303 Score = 33.5 bits (75), Expect = 1.2 Identities = 62/327 (18%), Positives = 111/327 (33%), Gaps = 30/327 (9%) Query: 845 QVPSSVSSPDDAMVSPLKPAPKMTRDTGT----APFAPNLEEINNILESKFKSRASNAQA 900 ++P S + S L P T T A +P + ++ S + ++ + Sbjct: 2342 RMPVSTTMVASFETSTLSTTPADTSTPVTTYSQAGSSPTTADDTSMPTSTYSEGSTPLTS 2401 Query: 901 KPSSFFLQMQKRVSGHYVTSAAAKSVHAAPNPAPKELTNKEAERDMLPSPEQTLSPLSKM 960 P S + S H T + A T E P + +PL+ M Sbjct: 2402 VPVSTMPVVSSEASTHSTTPVDTSTPVTTSTEASSSPTTAEGTSIPTSPPSEGTTPLASM 2461 Query: 961 PHSVPQPLVEK---------TDDDVIGQAPAEASPPPIAPKPVTIPASQVSTQNLKTLKT 1011 P S P+V D EAS P + + +P S S + Sbjct: 2462 PVST-TPVVSSEAGTLSTTPVDTSTPMTTSTEASSSPTTAEDIVVPISTASEGSTLLTSI 2520 Query: 1012 FGAPRPYSSSGPSPFALAVVKRSQ---SFSKERTESPSASALVQPPANTEEGKTHSVNKF 1068 + P +S S + V + + ++ + + SA P + EG T Sbjct: 2521 PVSTTPVASPEASTLSTTPVDSNSPVVTSTEISSSATSAEGTSMPTSTYSEGST------ 2574 Query: 1069 VDIPQLGVSDKENNSAHNEQNSQIPTPTDGPSFTVMRQSSLTFQSSDPEQMRQSLLTAIR 1128 + + VS K A +E ++ TP D T + ++ T SS P + + + Sbjct: 2575 -PLRSMPVSTKP--LASSEASTLSTTPVD----TSIPVTTSTETSSSPTTAKDTSMPIST 2627 Query: 1129 SGEAAAKLKRVTIPSNTISVNGRSRLS 1155 E + L + + + ++ + S LS Sbjct: 2628 PSEVSTSLTSILVSTMPVASSEASTLS 2654 >gi|189181720 proteoglycan 4 isoform B [Homo sapiens] Length = 1363 Score = 46.6 bits (109), Expect = 1e-04 Identities = 113/593 (19%), Positives = 196/593 (33%), Gaps = 64/593 (10%) Query: 457 EEIDEKEELSEVPKVEAENISPKSQDIPFVSTDIINTLKNDPDSALGNGSGEFSQNSMEE 516 +++ E EE++E V +EN S S+ I +K+ +SA + + + Sbjct: 105 KKVIESEEITEEHSV-SENQESSSSSSSSSSSSTIRKIKSSKNSAANRELQKKLKVKDNK 163 Query: 517 KQETKSTDGQEPHSVVYDTSNGKKVVD----------SIRNLKSLGPNQENVQ--NEIIV 564 K TK +P VV + +G D + N S P + N Sbjct: 164 KNRTKKKPTPKP-PVVDEAGSGLDNGDFKVTTPDTSTTQHNKVSTSPKITTAKPINPRPS 222 Query: 565 YPENTEDNMKNGV---KKTEINVEGVAKNNNIDMEVERPSNSEAHETDTAISYKENHLAA 621 P N++ + + + K+T + + N + + A ET + LA Sbjct: 223 LPPNSDTSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAP 282 Query: 622 SSVPDQKLNQPSAEKTKDAAIQTTPSCNSFDGKHQDHNLSDSKVEECVQTSNNNISTQHS 681 +S K P AE T TTP + + + + + S + + Sbjct: 283 TSKVLAKPT-PKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPA 341 Query: 682 CLSSQDSVNTSREFRSQGTLIIHSEDPLTVKDPICAHGNDDLLPPVDRIDKNSTASYLKN 741 +++ + T +E P T K+P + P K + K+ Sbjct: 342 PTTTKSAPTTPKE-----------PAPTTTKEPAPTTPKE----PAPTTTKEPAPTTTKS 386 Query: 742 YPLYRQDYNPKP--KPSNEITREYIPKIGMTTYKIVPPKSLEISKDWQSETIEYKDDQDM 799 P ++ P KP+ +E P TT K P + + E + Sbjct: 387 APTTPKEPAPTTPKKPAPTTPKEPAP----TTPKEPTPTTPKEPAPTTKEPAPTTPKEPA 442 Query: 800 HALGKKHTHENVKETAIQTEDSAISESPEEPLPNLKPKPNLRTEHQVPSSVSSP-----D 854 KK KE A T + +EP P +P T P++ P Sbjct: 443 PTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTK 502 Query: 855 DAMVSPLKPAPKMTRDTG-TAPFAPNLEEINNILESKFKSRASNAQAKPSSFFLQMQKRV 913 A +P +P+P T++ T P P + K A +P+ Sbjct: 503 SAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAP--------- 553 Query: 914 SGHYVTSAAAKSVHAAPNPAPKELTNKEAERDMLPSPEQTLSPLSKMPHSVPQPLVEKTD 973 T A + P P + T + + P+ + L+P + P+ T Sbjct: 554 ---TTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAP------TTPEKPAPTTP 604 Query: 974 DDVIGQAPAEASP-PPIAPKPVTIPASQVSTQNLKTLKTFGAPRPYSSSGPSP 1025 +++ P E +P P P P T A+ +T T P P + P+P Sbjct: 605 EELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAP 657 Score = 42.7 bits (99), Expect = 0.002 Identities = 95/495 (19%), Positives = 164/495 (33%), Gaps = 79/495 (15%) Query: 656 QDHNLSDSKVEECVQTSNNNISTQHSCLSSQDSV---NTSREFRSQGTLIIHSEDPLTVK 712 ++H++S+++ +S+++ ST SS++S ++ + + ++ T K Sbjct: 115 EEHSVSENQESSSSSSSSSSSSTIRKIKSSKNSAANRELQKKLKVKDNKKNRTKKKPTPK 174 Query: 713 DPICAHGNDDL--------LPPVDRIDKNSTASYLKNYPLYRQDYNPKPK--PSNEITRE 762 P+ L P N ++ K + NP+P P+++ ++E Sbjct: 175 PPVVDEAGSGLDNGDFKVTTPDTSTTQHNKVSTSPKITTA--KPINPRPSLPPNSDTSKE 232 Query: 763 YIPKIGMTTY---KIVPPKSLEISKDWQSETIEYKDDQDMHALGKKH------------- 806 + T K + + S D + +T K+ Q + K Sbjct: 233 TSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAKPTP 292 Query: 807 -THENVKETAIQTEDSAISESPEEPLPNLKPKPNLRTEHQVPSSVSSPDDAMVSPLKPAP 865 K A+ T +P+EP +P P+++ S A +P +PAP Sbjct: 293 KAETTTKGPALTTPKEPTPTTPKEPASTTPKEP-------TPTTIKS---APTTPKEPAP 342 Query: 866 KMTRDTGTAPFAPNLEEINNILESKFKSRASNAQAKPSSFFLQMQKRVSGHYVTSAAAKS 925 T+ T P P + K A +P+ T+ +A + Sbjct: 343 TTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAP-------------TTTKSAPT 389 Query: 926 VHAAPNPA----PKELTNKEAERDMLPSPEQTLSPLSKMPHSVPQPLVEKTDDDVIGQAP 981 P P P T KE P+P P P P P T + P Sbjct: 390 TPKEPAPTTPKKPAPTTPKE------PAPTTPKEPTPTTPKE-PAP----TTKEPAPTTP 438 Query: 982 AEASP-PPIAPKPVTIPASQVSTQNLKTLKTFGAPRPYSSSGPSPFALAVVKRSQSFSKE 1040 E +P P P P T +T T P P + P+P K + + +KE Sbjct: 439 KEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAP---TTTKSAPTTTKE 495 Query: 1041 RTESPSASALVQP----PANTEE-GKTHSVNKFVDIPQLGVSDKENNSAHNEQNSQIPTP 1095 + + SA P P T+E T P+ A PT Sbjct: 496 PAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTT 555 Query: 1096 TDGPSFTVMRQSSLT 1110 T P+ T ++ + T Sbjct: 556 TKKPAPTTPKEPAPT 570 Score = 39.7 bits (91), Expect = 0.017 Identities = 60/274 (21%), Positives = 97/274 (35%), Gaps = 43/274 (15%) Query: 251 RDQTASAPATPLVNKHRPTFTRSNTISKPYISNTLPSDAPK--KRRAPLPPMPASQSVPQ 308 ++ + P P + PT T+ T S T AP K AP P + + P+ Sbjct: 677 KEPAPTTPKKPAPKELAPTTTKEPT------STTCDKPAPTTPKGTAPTTPKEPAPTTPK 730 Query: 309 DLAHIQERPASCIVKSMSVDETDKSPCE---AGRVRAGSLQLSSMSAGNSSLRRT----- 360 + A + + T K P A G +S ++ + T Sbjct: 731 EPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTP 790 Query: 361 --------KRKAPSPPSKIPPHQSDENSRVTALQPV------DGVPPDSASEA------N 400 K+ AP+ P PP S+ ++ T +P D P+ ++E N Sbjct: 791 KEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALEN 850 Query: 401 SPEELSSPETFHPGLSSQEQCTAPKLMEETSVFECPGTPEAAITSLTSGISSDYSLEEID 460 SP+E P T P + E T K ++T+ + TPE + T+ Sbjct: 851 SPKEPGVPTTKTPAATKPEMTTTAK--DKTTERDLRTTPE----TTTAAPKMTKETATTT 904 Query: 461 EKEELSEVPKVEAENISPKSQD-IPFVSTDIINT 493 EK S++ + S +QD PF T + T Sbjct: 905 EKTTESKITATTTQVTSTTTQDTTPFKITTLKTT 938 Score = 38.9 bits (89), Expect = 0.029 Identities = 162/862 (18%), Positives = 284/862 (32%), Gaps = 115/862 (13%) Query: 351 SAGNSSLRRTKRKAPSPPSKIPPHQSDENSRVTALQPVDGVPPDSASEANSPEELSSPET 410 S + +++ T +++P PP+K + E+ +T V S+S ++S SS T Sbjct: 82 SGASQTIKSTTKRSPKPPNKKKTKKVIESEEITEEHSVSENQESSSSSSSS----SSSST 137 Query: 411 FHPGLSSQEQCTAPKLMEETSVFE--------CPGTPEAAITSLTSGI-SSDYSLEEID- 460 SS+ +L ++ V + P + SG+ + D+ + D Sbjct: 138 IRKIKSSKNSAANRELQKKLKVKDNKKNRTKKKPTPKPPVVDEAGSGLDNGDFKVTTPDT 197 Query: 461 ---EKEELSEVPKV-EAENISPKSQDIPFVSTDIINTLKNDPDSALGNGSGEFSQNSMEE 516 + ++S PK+ A+ I+P+ P T +L + ++ + E + + Sbjct: 198 STTQHNKVSTSPKITTAKPINPRPSLPPNSDTSKETSLTVNKETTV-----ETKETTTTN 252 Query: 517 KQETKSTDGQEPHSVVYDTSNGKKVVDSIRNLKSLGPNQENVQNEIIVYPENTEDNMKNG 576 KQ STDG+E + +T + +K + K L P ++++ P + G Sbjct: 253 KQ--TSTDGKEKTTSAKETQSIEKT-----SAKDLAPT-----SKVLAKPTPKAETTTKG 300 Query: 577 VKKTEINVEGVAKNNNIDMEVERPSNSEAHETDTAI-----SYKENHLAASSVPDQKLNQ 631 T K E S + T T I + KE + + Sbjct: 301 PALT------TPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKE 354 Query: 632 PSAEKTKDAAIQTTPSCNSFDGKHQDHNLSDSKVEECVQTSNNNISTQHSCLSSQDSVNT 691 P+ TK+ A T K + S + + + + T Sbjct: 355 PAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTT 414 Query: 692 SREFRSQGTLIIHSEDPLTVKDPICAHGNDDLLPPVDRIDKNSTASYLKNYPLYRQDYNP 751 +E T E T K+P + P K + K P P Sbjct: 415 PKE----PTPTTPKEPAPTTKEPAPTTPKE----PAPTAPKKPAPTTPKE-PAPTTPKEP 465 Query: 752 KP----KPSNEITREYIP---KIGMTTYKIVPPKSLEISKDWQSETIEYKDDQDMHALGK 804 P +PS +E P K TT K P + + + E + K Sbjct: 466 APTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPK 525 Query: 805 KHTHENVKETAIQTEDSAISESPEEPLPNLKPKPNLRTEHQVPSSV-------------- 850 + K+ A T +P+EP P KP T + + Sbjct: 526 EPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTP 585 Query: 851 SSPDD-AMVSPLKPAPKMTRD---------TGTAP----------FAPNLEEINNILESK 890 ++P+ A +P KPAP + T T P APN + K Sbjct: 586 TTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPK 645 Query: 891 FKSRASNAQAKPSSFFLQMQKRVSGHYVTSAAAKSVHAAPNPAPKEL--------TNKEA 942 + + + P++ G T+ + PAPKEL T+ Sbjct: 646 EPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTC 705 Query: 943 ERDMLPSPEQTLSPLSKMPHSV----PQPLVEKTDDDVIGQAPAEASPPPIAPKPVTIPA 998 ++ +P+ T K P P P K + PA +P APK + Sbjct: 706 DKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTT 765 Query: 999 SQVSTQNLKTLKTFGAPRPYSSSGPSPFALAVVKRSQSFSKERTESPSASALVQPPANTE 1058 ++ T P+ + + P A K+ + E P ++ V P T+ Sbjct: 766 TKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPE--TPPPTTSEVSTPTTTK 823 Query: 1059 EGKTHSVNKFVDIPQLGVSDKENNSAHNEQNSQIPTPTDGPSFTVMRQSSLTFQSSDPEQ 1118 E T + P+L ++ + +PT T P+ T + +T + D + Sbjct: 824 EPTTIHKSPDESTPELSAEPTPKALENSPKEPGVPT-TKTPAAT---KPEMTTTAKD-KT 878 Query: 1119 MRQSLLTAIRSGEAAAKLKRVT 1140 + L T + AA K+ + T Sbjct: 879 TERDLRTTPETTTAAPKMTKET 900 Score = 37.0 bits (84), Expect = 0.11 Identities = 53/262 (20%), Positives = 87/262 (33%), Gaps = 27/262 (10%) Query: 807 THENVKETAIQTEDSAISESPEEPLPNLKPKPNLRTEHQVPSSVSSPDDAMVSPLKPAPK 866 T V E + I +SP+E P L +P + P P + KP Sbjct: 812 TTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEPGVPTTKTPAATKPEMT 871 Query: 867 MT-RDTGTAPFAPNLEEINNILESKFKSRASNAQAKPSSFFLQMQKRVSGHYVTSAAAKS 925 T +D T E K A+ + S +V+ Sbjct: 872 TTAKDKTTERDLRTTPETTTAAPKMTKETATTTEKTTESKITATTTQVTSTTTQDTTPFK 931 Query: 926 VHAAPNP--APKELTNKE--AERDMLPSPEQTLSPLSKMPHS---VPQPLVEKTDDDVIG 978 + APK T K+ +++ PE+T P + +S P+P Sbjct: 932 ITTLKTTTLAPKVTTTKKTITTTEIMNKPEETAKPKDRATNSKATTPKP----------- 980 Query: 979 QAPAEASPPPIA-PKPVTIPASQVSTQNLKTLKTFGAPRPYSSSGPSPFALAVVKRSQSF 1037 Q P +A P + KP T+P ++ KT PR +S+ P + + + Sbjct: 981 QKPTKAPKKPTSTKKPKTMP-------RVRKPKTTPTPRKMTSTMPELNPTSRIAEAMLQ 1033 Query: 1038 SKERTESPSASALVQPPANTEE 1059 + R S LV+ +E+ Sbjct: 1034 TTTRPNQTPNSKLVEVNPKSED 1055 Score = 36.2 bits (82), Expect = 0.19 Identities = 39/196 (19%), Positives = 68/196 (34%), Gaps = 6/196 (3%) Query: 247 SKKKRDQTASAPATPLVNKHRPTFTRSNTISKPYISNTLPSDAPKKRRAPLPPMPASQSV 306 +K+ T PA K PT + + P P+ K +P P + + Sbjct: 430 TKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTP----KEPAPTTTKEPSPTTPKEPAPTT 485 Query: 307 PQDLAHIQERPASCIVKSMSVDETDKSPCEAGRVRAGSLQLSSMSAGNSSLRRT-KRKAP 365 + + PA KS + SP + + + + T K AP Sbjct: 486 TKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAP 545 Query: 366 SPPSKIPPHQSDENSRVTALQPVDGVPPDSASEANSPEELSSPETFHPGLSSQEQCTAPK 425 + P + P + + + T +P P ++A ++PE P + T P+ Sbjct: 546 TTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPE 605 Query: 426 LMEETSVFE-CPGTPE 440 + T+ E P TPE Sbjct: 606 ELAPTTPEEPTPTTPE 621 Score = 35.8 bits (81), Expect = 0.24 Identities = 48/202 (23%), Positives = 73/202 (36%), Gaps = 10/202 (4%) Query: 247 SKKKRDQTASAPATPLVNKHRPTFTR----SNTISKPYISNTLPSDAPKKRRAPLPPMPA 302 +K+ T PA P K PT T+ + T S P PS K AP P Sbjct: 470 TKEPSPTTPKEPA-PTTTKSAPTTTKEPAPTTTKSAPTTPKE-PSPTTTKEPAPTTPKEP 527 Query: 303 SQSVPQDLAHIQER-PASCIVKSMSVDETDKSPCEAGRVRAGSLQLSSMSAGNSSLRRT- 360 + + P+ A + PA K + T K + A + + L T Sbjct: 528 APTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTT 587 Query: 361 -KRKAPSPPSKIPPHQSDENSRVTALQPVDGVPPDSASEANSPEELSSPETFHPGLSSQE 419 ++ AP+ P K P +E + T +P P + A ++P+ P + Sbjct: 588 PEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEP 647 Query: 420 QCTAPKLMEETSVFE-CPGTPE 440 T PK T+ E P TP+ Sbjct: 648 APTTPKEPAPTTPKETAPTTPK 669 Score = 35.8 bits (81), Expect = 0.24 Identities = 58/266 (21%), Positives = 94/266 (35%), Gaps = 37/266 (13%) Query: 257 APATPLVNKHRPTFTRSNTISKPY--ISNTLPSDAPK--KRRAPLPPMPASQSVPQDLAH 312 AP TP + PT T + P T + AP K AP P + + P++ A Sbjct: 600 APTTP--EELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAP 657 Query: 313 IQERPASCIVKSMSVDETDKSPCEAGRVRAGSLQLSSMSAGNSSLRRTKRKAPSPPSKIP 372 + + + T K P + +L+ + + + AP+ P Sbjct: 658 TTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTA 717 Query: 373 PHQSDENSRVTALQPVDGVPPDSA-----------SEANSPEELSSPETFHPGLSSQEQ- 420 P E + T +P P +A + +P+EL+ T P ++ ++ Sbjct: 718 PTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKP 777 Query: 421 -CTAPKLMEETSVFE---------CPGTPEAAITSLTSGISSDYSLEE--------IDEK 462 T PK T+ E P TPE TS +S+ + +E + Sbjct: 778 APTTPKETAPTTPKEPAPTTPKKPAPTTPETP-PPTTSEVSTPTTTKEPTTIHKSPDEST 836 Query: 463 EELSEVPKVEAENISPKSQDIPFVST 488 ELS P +A SPK +P T Sbjct: 837 PELSAEPTPKALENSPKEPGVPTTKT 862 Score = 30.8 bits (68), Expect = 7.9 Identities = 47/230 (20%), Positives = 76/230 (33%), Gaps = 28/230 (12%) Query: 222 SCQISQNLDIMKEKENKGFFSFFQRSKKKRDQTASAPATPLVNKHRPTFTR--SNTISKP 279 S + +Q+++ K+ + K + T PA + PT + ++T K Sbjct: 265 SAKETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKE 324 Query: 280 YISNTLPSDAPKKRRAPLPPMPASQ-SVPQDLAHIQERPASCIVKSMSVDETDKSPCEAG 338 T+ S AP + P P S + P++ A + + T K P Sbjct: 325 PTPTTIKS-APTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAP-- 381 Query: 339 RVRAGSLQLSSMSAGNSSLRRTKRKAPSPPSKIPPHQSDENSRVTALQPVDGVPPDSASE 398 + S+ K AP+ P K P E + T +P P + A Sbjct: 382 ------------TTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPT 429 Query: 399 ANSPEELSSPETFHPGLSSQEQCTAPKLMEETSVFE-CPGTPEAAITSLT 447 P P + TAPK T+ E P TP+ + T Sbjct: 430 TKEPA---------PTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTT 470 >gi|67190163 proteoglycan 4 isoform A [Homo sapiens] Length = 1404 Score = 46.6 bits (109), Expect = 1e-04 Identities = 113/593 (19%), Positives = 196/593 (33%), Gaps = 64/593 (10%) Query: 457 EEIDEKEELSEVPKVEAENISPKSQDIPFVSTDIINTLKNDPDSALGNGSGEFSQNSMEE 516 +++ E EE++E V +EN S S+ I +K+ +SA + + + Sbjct: 146 KKVIESEEITEEHSV-SENQESSSSSSSSSSSSTIRKIKSSKNSAANRELQKKLKVKDNK 204 Query: 517 KQETKSTDGQEPHSVVYDTSNGKKVVD----------SIRNLKSLGPNQENVQ--NEIIV 564 K TK +P VV + +G D + N S P + N Sbjct: 205 KNRTKKKPTPKP-PVVDEAGSGLDNGDFKVTTPDTSTTQHNKVSTSPKITTAKPINPRPS 263 Query: 565 YPENTEDNMKNGV---KKTEINVEGVAKNNNIDMEVERPSNSEAHETDTAISYKENHLAA 621 P N++ + + + K+T + + N + + A ET + LA Sbjct: 264 LPPNSDTSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAP 323 Query: 622 SSVPDQKLNQPSAEKTKDAAIQTTPSCNSFDGKHQDHNLSDSKVEECVQTSNNNISTQHS 681 +S K P AE T TTP + + + + + S + + Sbjct: 324 TSKVLAKPT-PKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPA 382 Query: 682 CLSSQDSVNTSREFRSQGTLIIHSEDPLTVKDPICAHGNDDLLPPVDRIDKNSTASYLKN 741 +++ + T +E P T K+P + P K + K+ Sbjct: 383 PTTTKSAPTTPKE-----------PAPTTTKEPAPTTPKE----PAPTTTKEPAPTTTKS 427 Query: 742 YPLYRQDYNPKP--KPSNEITREYIPKIGMTTYKIVPPKSLEISKDWQSETIEYKDDQDM 799 P ++ P KP+ +E P TT K P + + E + Sbjct: 428 APTTPKEPAPTTPKKPAPTTPKEPAP----TTPKEPTPTTPKEPAPTTKEPAPTTPKEPA 483 Query: 800 HALGKKHTHENVKETAIQTEDSAISESPEEPLPNLKPKPNLRTEHQVPSSVSSP-----D 854 KK KE A T + +EP P +P T P++ P Sbjct: 484 PTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTK 543 Query: 855 DAMVSPLKPAPKMTRDTG-TAPFAPNLEEINNILESKFKSRASNAQAKPSSFFLQMQKRV 913 A +P +P+P T++ T P P + K A +P+ Sbjct: 544 SAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAP--------- 594 Query: 914 SGHYVTSAAAKSVHAAPNPAPKELTNKEAERDMLPSPEQTLSPLSKMPHSVPQPLVEKTD 973 T A + P P + T + + P+ + L+P + P+ T Sbjct: 595 ---TTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAP------TTPEKPAPTTP 645 Query: 974 DDVIGQAPAEASP-PPIAPKPVTIPASQVSTQNLKTLKTFGAPRPYSSSGPSP 1025 +++ P E +P P P P T A+ +T T P P + P+P Sbjct: 646 EELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAP 698 Score = 42.7 bits (99), Expect = 0.002 Identities = 95/495 (19%), Positives = 164/495 (33%), Gaps = 79/495 (15%) Query: 656 QDHNLSDSKVEECVQTSNNNISTQHSCLSSQDSV---NTSREFRSQGTLIIHSEDPLTVK 712 ++H++S+++ +S+++ ST SS++S ++ + + ++ T K Sbjct: 156 EEHSVSENQESSSSSSSSSSSSTIRKIKSSKNSAANRELQKKLKVKDNKKNRTKKKPTPK 215 Query: 713 DPICAHGNDDL--------LPPVDRIDKNSTASYLKNYPLYRQDYNPKPK--PSNEITRE 762 P+ L P N ++ K + NP+P P+++ ++E Sbjct: 216 PPVVDEAGSGLDNGDFKVTTPDTSTTQHNKVSTSPKITTA--KPINPRPSLPPNSDTSKE 273 Query: 763 YIPKIGMTTY---KIVPPKSLEISKDWQSETIEYKDDQDMHALGKKH------------- 806 + T K + + S D + +T K+ Q + K Sbjct: 274 TSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAKPTP 333 Query: 807 -THENVKETAIQTEDSAISESPEEPLPNLKPKPNLRTEHQVPSSVSSPDDAMVSPLKPAP 865 K A+ T +P+EP +P P+++ S A +P +PAP Sbjct: 334 KAETTTKGPALTTPKEPTPTTPKEPASTTPKEP-------TPTTIKS---APTTPKEPAP 383 Query: 866 KMTRDTGTAPFAPNLEEINNILESKFKSRASNAQAKPSSFFLQMQKRVSGHYVTSAAAKS 925 T+ T P P + K A +P+ T+ +A + Sbjct: 384 TTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAP-------------TTTKSAPT 430 Query: 926 VHAAPNPA----PKELTNKEAERDMLPSPEQTLSPLSKMPHSVPQPLVEKTDDDVIGQAP 981 P P P T KE P+P P P P P T + P Sbjct: 431 TPKEPAPTTPKKPAPTTPKE------PAPTTPKEPTPTTPKE-PAP----TTKEPAPTTP 479 Query: 982 AEASP-PPIAPKPVTIPASQVSTQNLKTLKTFGAPRPYSSSGPSPFALAVVKRSQSFSKE 1040 E +P P P P T +T T P P + P+P K + + +KE Sbjct: 480 KEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAP---TTTKSAPTTTKE 536 Query: 1041 RTESPSASALVQP----PANTEE-GKTHSVNKFVDIPQLGVSDKENNSAHNEQNSQIPTP 1095 + + SA P P T+E T P+ A PT Sbjct: 537 PAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTT 596 Query: 1096 TDGPSFTVMRQSSLT 1110 T P+ T ++ + T Sbjct: 597 TKKPAPTTPKEPAPT 611 Score = 39.7 bits (91), Expect = 0.017 Identities = 60/274 (21%), Positives = 97/274 (35%), Gaps = 43/274 (15%) Query: 251 RDQTASAPATPLVNKHRPTFTRSNTISKPYISNTLPSDAPK--KRRAPLPPMPASQSVPQ 308 ++ + P P + PT T+ T S T AP K AP P + + P+ Sbjct: 718 KEPAPTTPKKPAPKELAPTTTKEPT------STTCDKPAPTTPKGTAPTTPKEPAPTTPK 771 Query: 309 DLAHIQERPASCIVKSMSVDETDKSPCE---AGRVRAGSLQLSSMSAGNSSLRRT----- 360 + A + + T K P A G +S ++ + T Sbjct: 772 EPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTP 831 Query: 361 --------KRKAPSPPSKIPPHQSDENSRVTALQPV------DGVPPDSASEA------N 400 K+ AP+ P PP S+ ++ T +P D P+ ++E N Sbjct: 832 KEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALEN 891 Query: 401 SPEELSSPETFHPGLSSQEQCTAPKLMEETSVFECPGTPEAAITSLTSGISSDYSLEEID 460 SP+E P T P + E T K ++T+ + TPE + T+ Sbjct: 892 SPKEPGVPTTKTPAATKPEMTTTAK--DKTTERDLRTTPE----TTTAAPKMTKETATTT 945 Query: 461 EKEELSEVPKVEAENISPKSQD-IPFVSTDIINT 493 EK S++ + S +QD PF T + T Sbjct: 946 EKTTESKITATTTQVTSTTTQDTTPFKITTLKTT 979 Score = 38.9 bits (89), Expect = 0.029 Identities = 162/862 (18%), Positives = 284/862 (32%), Gaps = 115/862 (13%) Query: 351 SAGNSSLRRTKRKAPSPPSKIPPHQSDENSRVTALQPVDGVPPDSASEANSPEELSSPET 410 S + +++ T +++P PP+K + E+ +T V S+S ++S SS T Sbjct: 123 SGASQTIKSTTKRSPKPPNKKKTKKVIESEEITEEHSVSENQESSSSSSSS----SSSST 178 Query: 411 FHPGLSSQEQCTAPKLMEETSVFE--------CPGTPEAAITSLTSGI-SSDYSLEEID- 460 SS+ +L ++ V + P + SG+ + D+ + D Sbjct: 179 IRKIKSSKNSAANRELQKKLKVKDNKKNRTKKKPTPKPPVVDEAGSGLDNGDFKVTTPDT 238 Query: 461 ---EKEELSEVPKV-EAENISPKSQDIPFVSTDIINTLKNDPDSALGNGSGEFSQNSMEE 516 + ++S PK+ A+ I+P+ P T +L + ++ + E + + Sbjct: 239 STTQHNKVSTSPKITTAKPINPRPSLPPNSDTSKETSLTVNKETTV-----ETKETTTTN 293 Query: 517 KQETKSTDGQEPHSVVYDTSNGKKVVDSIRNLKSLGPNQENVQNEIIVYPENTEDNMKNG 576 KQ STDG+E + +T + +K + K L P ++++ P + G Sbjct: 294 KQ--TSTDGKEKTTSAKETQSIEKT-----SAKDLAPT-----SKVLAKPTPKAETTTKG 341 Query: 577 VKKTEINVEGVAKNNNIDMEVERPSNSEAHETDTAI-----SYKENHLAASSVPDQKLNQ 631 T K E S + T T I + KE + + Sbjct: 342 PALT------TPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKE 395 Query: 632 PSAEKTKDAAIQTTPSCNSFDGKHQDHNLSDSKVEECVQTSNNNISTQHSCLSSQDSVNT 691 P+ TK+ A T K + S + + + + T Sbjct: 396 PAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTT 455 Query: 692 SREFRSQGTLIIHSEDPLTVKDPICAHGNDDLLPPVDRIDKNSTASYLKNYPLYRQDYNP 751 +E T E T K+P + P K + K P P Sbjct: 456 PKE----PTPTTPKEPAPTTKEPAPTTPKE----PAPTAPKKPAPTTPKE-PAPTTPKEP 506 Query: 752 KP----KPSNEITREYIP---KIGMTTYKIVPPKSLEISKDWQSETIEYKDDQDMHALGK 804 P +PS +E P K TT K P + + + E + K Sbjct: 507 APTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPK 566 Query: 805 KHTHENVKETAIQTEDSAISESPEEPLPNLKPKPNLRTEHQVPSSV-------------- 850 + K+ A T +P+EP P KP T + + Sbjct: 567 EPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTP 626 Query: 851 SSPDD-AMVSPLKPAPKMTRD---------TGTAP----------FAPNLEEINNILESK 890 ++P+ A +P KPAP + T T P APN + K Sbjct: 627 TTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPK 686 Query: 891 FKSRASNAQAKPSSFFLQMQKRVSGHYVTSAAAKSVHAAPNPAPKEL--------TNKEA 942 + + + P++ G T+ + PAPKEL T+ Sbjct: 687 EPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTC 746 Query: 943 ERDMLPSPEQTLSPLSKMPHSV----PQPLVEKTDDDVIGQAPAEASPPPIAPKPVTIPA 998 ++ +P+ T K P P P K + PA +P APK + Sbjct: 747 DKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTT 806 Query: 999 SQVSTQNLKTLKTFGAPRPYSSSGPSPFALAVVKRSQSFSKERTESPSASALVQPPANTE 1058 ++ T P+ + + P A K+ + E P ++ V P T+ Sbjct: 807 TKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPE--TPPPTTSEVSTPTTTK 864 Query: 1059 EGKTHSVNKFVDIPQLGVSDKENNSAHNEQNSQIPTPTDGPSFTVMRQSSLTFQSSDPEQ 1118 E T + P+L ++ + +PT T P+ T + +T + D + Sbjct: 865 EPTTIHKSPDESTPELSAEPTPKALENSPKEPGVPT-TKTPAAT---KPEMTTTAKD-KT 919 Query: 1119 MRQSLLTAIRSGEAAAKLKRVT 1140 + L T + AA K+ + T Sbjct: 920 TERDLRTTPETTTAAPKMTKET 941 Score = 37.0 bits (84), Expect = 0.11 Identities = 53/262 (20%), Positives = 87/262 (33%), Gaps = 27/262 (10%) Query: 807 THENVKETAIQTEDSAISESPEEPLPNLKPKPNLRTEHQVPSSVSSPDDAMVSPLKPAPK 866 T V E + I +SP+E P L +P + P P + KP Sbjct: 853 TTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEPGVPTTKTPAATKPEMT 912 Query: 867 MT-RDTGTAPFAPNLEEINNILESKFKSRASNAQAKPSSFFLQMQKRVSGHYVTSAAAKS 925 T +D T E K A+ + S +V+ Sbjct: 913 TTAKDKTTERDLRTTPETTTAAPKMTKETATTTEKTTESKITATTTQVTSTTTQDTTPFK 972 Query: 926 VHAAPNP--APKELTNKE--AERDMLPSPEQTLSPLSKMPHS---VPQPLVEKTDDDVIG 978 + APK T K+ +++ PE+T P + +S P+P Sbjct: 973 ITTLKTTTLAPKVTTTKKTITTTEIMNKPEETAKPKDRATNSKATTPKP----------- 1021 Query: 979 QAPAEASPPPIA-PKPVTIPASQVSTQNLKTLKTFGAPRPYSSSGPSPFALAVVKRSQSF 1037 Q P +A P + KP T+P ++ KT PR +S+ P + + + Sbjct: 1022 QKPTKAPKKPTSTKKPKTMP-------RVRKPKTTPTPRKMTSTMPELNPTSRIAEAMLQ 1074 Query: 1038 SKERTESPSASALVQPPANTEE 1059 + R S LV+ +E+ Sbjct: 1075 TTTRPNQTPNSKLVEVNPKSED 1096 Score = 36.2 bits (82), Expect = 0.19 Identities = 39/196 (19%), Positives = 68/196 (34%), Gaps = 6/196 (3%) Query: 247 SKKKRDQTASAPATPLVNKHRPTFTRSNTISKPYISNTLPSDAPKKRRAPLPPMPASQSV 306 +K+ T PA K PT + + P P+ K +P P + + Sbjct: 471 TKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTP----KEPAPTTTKEPSPTTPKEPAPTT 526 Query: 307 PQDLAHIQERPASCIVKSMSVDETDKSPCEAGRVRAGSLQLSSMSAGNSSLRRT-KRKAP 365 + + PA KS + SP + + + + T K AP Sbjct: 527 TKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAP 586 Query: 366 SPPSKIPPHQSDENSRVTALQPVDGVPPDSASEANSPEELSSPETFHPGLSSQEQCTAPK 425 + P + P + + + T +P P ++A ++PE P + T P+ Sbjct: 587 TTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPE 646 Query: 426 LMEETSVFE-CPGTPE 440 + T+ E P TPE Sbjct: 647 ELAPTTPEEPTPTTPE 662 Score = 35.8 bits (81), Expect = 0.24 Identities = 48/202 (23%), Positives = 73/202 (36%), Gaps = 10/202 (4%) Query: 247 SKKKRDQTASAPATPLVNKHRPTFTR----SNTISKPYISNTLPSDAPKKRRAPLPPMPA 302 +K+ T PA P K PT T+ + T S P PS K AP P Sbjct: 511 TKEPSPTTPKEPA-PTTTKSAPTTTKEPAPTTTKSAPTTPKE-PSPTTTKEPAPTTPKEP 568 Query: 303 SQSVPQDLAHIQER-PASCIVKSMSVDETDKSPCEAGRVRAGSLQLSSMSAGNSSLRRT- 360 + + P+ A + PA K + T K + A + + L T Sbjct: 569 APTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTT 628 Query: 361 -KRKAPSPPSKIPPHQSDENSRVTALQPVDGVPPDSASEANSPEELSSPETFHPGLSSQE 419 ++ AP+ P K P +E + T +P P + A ++P+ P + Sbjct: 629 PEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEP 688 Query: 420 QCTAPKLMEETSVFE-CPGTPE 440 T PK T+ E P TP+ Sbjct: 689 APTTPKEPAPTTPKETAPTTPK 710 Score = 35.8 bits (81), Expect = 0.24 Identities = 58/266 (21%), Positives = 94/266 (35%), Gaps = 37/266 (13%) Query: 257 APATPLVNKHRPTFTRSNTISKPY--ISNTLPSDAPK--KRRAPLPPMPASQSVPQDLAH 312 AP TP + PT T + P T + AP K AP P + + P++ A Sbjct: 641 APTTP--EELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAP 698 Query: 313 IQERPASCIVKSMSVDETDKSPCEAGRVRAGSLQLSSMSAGNSSLRRTKRKAPSPPSKIP 372 + + + T K P + +L+ + + + AP+ P Sbjct: 699 TTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTA 758 Query: 373 PHQSDENSRVTALQPVDGVPPDSA-----------SEANSPEELSSPETFHPGLSSQEQ- 420 P E + T +P P +A + +P+EL+ T P ++ ++ Sbjct: 759 PTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKP 818 Query: 421 -CTAPKLMEETSVFE---------CPGTPEAAITSLTSGISSDYSLEE--------IDEK 462 T PK T+ E P TPE TS +S+ + +E + Sbjct: 819 APTTPKETAPTTPKEPAPTTPKKPAPTTPETP-PPTTSEVSTPTTTKEPTTIHKSPDEST 877 Query: 463 EELSEVPKVEAENISPKSQDIPFVST 488 ELS P +A SPK +P T Sbjct: 878 PELSAEPTPKALENSPKEPGVPTTKT 903 Score = 30.8 bits (68), Expect = 7.9 Identities = 47/230 (20%), Positives = 76/230 (33%), Gaps = 28/230 (12%) Query: 222 SCQISQNLDIMKEKENKGFFSFFQRSKKKRDQTASAPATPLVNKHRPTFTR--SNTISKP 279 S + +Q+++ K+ + K + T PA + PT + ++T K Sbjct: 306 SAKETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKE 365 Query: 280 YISNTLPSDAPKKRRAPLPPMPASQ-SVPQDLAHIQERPASCIVKSMSVDETDKSPCEAG 338 T+ S AP + P P S + P++ A + + T K P Sbjct: 366 PTPTTIKS-APTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAP-- 422 Query: 339 RVRAGSLQLSSMSAGNSSLRRTKRKAPSPPSKIPPHQSDENSRVTALQPVDGVPPDSASE 398 + S+ K AP+ P K P E + T +P P + A Sbjct: 423 ------------TTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPT 470 Query: 399 ANSPEELSSPETFHPGLSSQEQCTAPKLMEETSVFE-CPGTPEAAITSLT 447 P P + TAPK T+ E P TP+ + T Sbjct: 471 TKEPA---------PTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTT 511 >gi|148596949 nucleolar and coiled-body phosphoprotein 1 [Homo sapiens] Length = 699 Score = 45.1 bits (105), Expect = 4e-04 Identities = 94/460 (20%), Positives = 164/460 (35%), Gaps = 55/460 (11%) Query: 248 KKKRDQTASAPATPLVNKHRPTFTRSNTISKPYISNTLPSDAPK--KRRAPLPPMPASQS 305 K + Q +A A P K + + S++ +P N P P K + PP PA ++ Sbjct: 148 KGVKPQAKAAKAPPKKAKSSDSDSDSSSEDEPP-KNQKPKITPVTVKAQTKAPPKPA-RA 205 Query: 306 VPQDLAHIQERPASCIVKSMSVDETD-------------------KSPCEAGRV--RAGS 344 P+ +S S S D+++ K+P +A R S Sbjct: 206 APKIANGKAASSSSSSSSSSSSDDSEEEKAAATPKKTVPKKQVVAKAPVKAATTPTRKSS 265 Query: 345 LQLSSMSAGNSSLRRTKRKAPSPPSKIPPHQSDENSRVTALQPVDGVPPDSASEANSPEE 404 S S ++ + P P S +PP + + QP P A E P E Sbjct: 266 SSEDSSSDEEEEQKKPMKNKPGPYSSVPPPSAPPPKKSLGTQP-----PKKAVEKQQPVE 320 Query: 405 LSSPETFHPGLSSQEQCTAP-KLMEETSVFECPGTPEAAITSLTSGISSDYSLEEIDEKE 463 S + SS+E+ P K + + + P +AA + SSD S + E + Sbjct: 321 SSEDSSDESDSSSEEEKKPPTKAVVSKATTKPPPAKKAAES------SSDSSDSDSSEDD 374 Query: 464 ELSEVPKVEAENISPKSQDIPFVSTDIINTL-KNDPDSALGNGSGEFSQ--NSMEEKQET 520 E P +N S K P V+T P +G G ++ +S ++E+ Sbjct: 375 EAPSKPAGTTKNSSNK----PAVTTKSPAVKPAAAPKQPVGGGQKLLTRKADSSSSEEES 430 Query: 521 KSTDGQEPHSVVYDT---SNGKKVVDSIRNLKSLGPNQENVQNEIIVYPENTEDNMKNGV 577 S++ ++ +V T + K + G + ++ E E K+ V Sbjct: 431 SSSEEEKTKKMVATTKPKATAKAALSLPAKQAPQGSRDSSSDSDSSSSEEEEEKTSKSAV 490 Query: 578 KKTEINVE-GVAKNNNIDMEVERPSNSEAHETDTAISYKENHLAASSVPDQKLNQPSAEK 636 KK V G A + + + +S + +D + +E L P +P A K Sbjct: 491 KKKPQKVAGGAAPSKPASAKKGKAESSNSSSSDDSSEEEEEKLKGKGSP-----RPQAPK 545 Query: 637 TKDAAIQTTPSCNSFDGKHQDHNLSDSKVEECVQTSNNNI 676 + T N K+ + + K V + + ++ Sbjct: 546 ANGTSALTAQ--NGKAAKNSEEEEEEKKKAAVVVSKSGSL 583 Score = 42.4 bits (98), Expect = 0.003 Identities = 61/319 (19%), Positives = 114/319 (35%), Gaps = 10/319 (3%) Query: 818 TEDSAISESPEEPLPNLKPKPNLRTEHQVPSSVSSPDDAMVSPLKPAPKMTRDTGTAPFA 877 +EDS+ E E+ P +K KP + PS+ P K A + + ++ + Sbjct: 267 SEDSSSDEEEEQKKP-MKNKPGPYSSVPPPSAPPPKKSLGTQPPKKAVEKQQPVESSEDS 325 Query: 878 PNLEEINNILESKFKSRA--SNAQAKPSSFFLQMQKRVSGHYVTSAAAKSVHAAPNPAPK 935 + + ++ E K ++A S A KP + S+ + P K Sbjct: 326 SDESDSSSEEEKKPPTKAVVSKATTKPPPAKKAAESSSDSSDSDSSEDDEAPSKPAGTTK 385 Query: 936 ELTNKEAERDMLPSPEQTLSPLSKMPHSVPQPLVEKTDDDVIGQAPAEASPPPIAPKPVT 995 +NK A P+ + +P K P Q L+ + D + + +S K V Sbjct: 386 NSSNKPAVTTKSPAVKPAAAP--KQPVGGGQKLLTRKADSSSSEEESSSSEEEKTKKMVA 443 Query: 996 IPASQVSTQNLKTLKTFGAPR----PYSSSGPSPFALAVVKRSQSFSKERTESPSASALV 1051 + + + +L AP+ S S S K S+S K++ + + A Sbjct: 444 TTKPKATAKAALSLPAKQAPQGSRDSSSDSDSSSSEEEEEKTSKSAVKKKPQKVAGGAAP 503 Query: 1052 QPPANTEEGKTHSVNKFVDIPQLGVSDKENNSAHNEQNSQIPTPTDGPSFTVMRQSSLTF 1111 PA+ ++GK S N ++E Q P + T + Sbjct: 504 SKPASAKKGKAESSNS-SSSDDSSEEEEEKLKGKGSPRPQAPKANGTSALTAQNGKAAKN 562 Query: 1112 QSSDPEQMRQSLLTAIRSG 1130 + E+ +++ + +SG Sbjct: 563 SEEEEEEKKKAAVVVSKSG 581 >gi|55953110 retinoblastoma protein-binding zinc finger protein isoform c [Homo sapiens] Length = 1481 Score = 45.1 bits (105), Expect = 4e-04 Identities = 69/296 (23%), Positives = 109/296 (36%), Gaps = 36/296 (12%) Query: 804 KKHTHEN----VKET-AIQTEDSAISESPEEPLPNLKPKPNLRTEHQVPSSVSSPDDAMV 858 KKH ++ KE+ ++Q SA+ + +P + K L + + V +P D Sbjct: 653 KKHCSDSEGKEFKESHSVQPTCSAVKK--RKPTTCMLQKVLLNEYNGIDLPVENPADGTR 710 Query: 859 SP-----LKPAPKMTRDTGTAPFAPNLEEINNILESKFKSRASNAQAKPSSFFLQMQKRV 913 SP L+ P G+ AP +E ++ PSS LQ Sbjct: 711 SPSPCKSLEAQPDPDLGPGSGFPAPTVESTPDVC--------------PSSPALQTPSLS 756 Query: 914 SGHYVTSAAAKSVHAAPNPAPKELTNKEAERDMLPSPEQTLSPLSKMPHSVPQPLVEKTD 973 SG + + ++P P P LT +LP+ S PH P PL T Sbjct: 757 SGQ-LPPLLIPTDPSSPPPCPPVLTVATPPPPLLPTVPLPAPSSSASPHPCPSPLSNAT- 814 Query: 974 DDVIGQAPAEASPPPIAPKPVTIPASQVSTQNLKTLKTFGAPRPYSSSGPSPFALAVVKR 1033 Q+P P ++P P IP + L + + G P SSS S + + Sbjct: 815 ----AQSPLPILSPTVSPSPSPIP----PVEPLMSAASPGPPTLSSSSSSSSSSSSFSSS 866 Query: 1034 SQSFSKERTESPSASALVQPPANTEEGKTHSVNKFVDIPQLGVSDKENNSAHNEQN 1089 S S S + S++V N E K ++ G+ +E + EQ+ Sbjct: 867 SSSSSPSPPPLSAISSVVSSGDNLEASLPMISFKQEELENEGLKPREEPQSAAEQD 922 Score = 30.8 bits (68), Expect = 7.9 Identities = 46/213 (21%), Positives = 72/213 (33%), Gaps = 11/213 (5%) Query: 931 NPAPKELTNKEAERDMLPSPEQTLSPLSKMPHSVPQPLVEKTDDDVIGQAPAEASPPPIA 990 +P+P + + + D+ P + P P +T GQ P P + Sbjct: 711 SPSPCKSLEAQPDPDLGPGSGFPAPTVESTPDVCPSSPALQTPSLSSGQLPPLLIPTDPS 770 Query: 991 PKPVTIPASQVSTQNLKTLKTFGAPRPYSSSG----PSPFALAVVKRSQSFSKERTESPS 1046 P P V+T L T P P SS+ PSP + A + T SPS Sbjct: 771 SPPPCPPVLTVATPPPPLLPTVPLPAPSSSASPHPCPSPLSNATAQSPLPILSP-TVSPS 829 Query: 1047 ASALVQPPANTEEGKTHSVNKFVDIPQLGVSDKENNSAHNEQNSQIPTPTDGPSFTVMR- 1105 S + PP + S + S+ + +S P P S V Sbjct: 830 PSPI--PPVEPLMSAASPGPPTLSSSSSSSSSSSSFSSSSSSSSPSPPPLSAISSVVSSG 887 Query: 1106 ---QSSLTFQSSDPEQMRQSLLTAIRSGEAAAK 1135 ++SL S E++ L ++AA+ Sbjct: 888 DNLEASLPMISFKQEELENEGLKPREEPQSAAE 920 >gi|20336260 retinoblastoma protein-binding zinc finger protein isoform b [Homo sapiens] Length = 1682 Score = 45.1 bits (105), Expect = 4e-04 Identities = 69/296 (23%), Positives = 109/296 (36%), Gaps = 36/296 (12%) Query: 804 KKHTHEN----VKET-AIQTEDSAISESPEEPLPNLKPKPNLRTEHQVPSSVSSPDDAMV 858 KKH ++ KE+ ++Q SA+ + +P + K L + + V +P D Sbjct: 854 KKHCSDSEGKEFKESHSVQPTCSAVKK--RKPTTCMLQKVLLNEYNGIDLPVENPADGTR 911 Query: 859 SP-----LKPAPKMTRDTGTAPFAPNLEEINNILESKFKSRASNAQAKPSSFFLQMQKRV 913 SP L+ P G+ AP +E ++ PSS LQ Sbjct: 912 SPSPCKSLEAQPDPDLGPGSGFPAPTVESTPDVC--------------PSSPALQTPSLS 957 Query: 914 SGHYVTSAAAKSVHAAPNPAPKELTNKEAERDMLPSPEQTLSPLSKMPHSVPQPLVEKTD 973 SG + + ++P P P LT +LP+ S PH P PL T Sbjct: 958 SGQ-LPPLLIPTDPSSPPPCPPVLTVATPPPPLLPTVPLPAPSSSASPHPCPSPLSNAT- 1015 Query: 974 DDVIGQAPAEASPPPIAPKPVTIPASQVSTQNLKTLKTFGAPRPYSSSGPSPFALAVVKR 1033 Q+P P ++P P IP + L + + G P SSS S + + Sbjct: 1016 ----AQSPLPILSPTVSPSPSPIP----PVEPLMSAASPGPPTLSSSSSSSSSSSSFSSS 1067 Query: 1034 SQSFSKERTESPSASALVQPPANTEEGKTHSVNKFVDIPQLGVSDKENNSAHNEQN 1089 S S S + S++V N E K ++ G+ +E + EQ+ Sbjct: 1068 SSSSSPSPPPLSAISSVVSSGDNLEASLPMISFKQEELENEGLKPREEPQSAAEQD 1123 Score = 30.8 bits (68), Expect = 7.9 Identities = 46/213 (21%), Positives = 72/213 (33%), Gaps = 11/213 (5%) Query: 931 NPAPKELTNKEAERDMLPSPEQTLSPLSKMPHSVPQPLVEKTDDDVIGQAPAEASPPPIA 990 +P+P + + + D+ P + P P +T GQ P P + Sbjct: 912 SPSPCKSLEAQPDPDLGPGSGFPAPTVESTPDVCPSSPALQTPSLSSGQLPPLLIPTDPS 971 Query: 991 PKPVTIPASQVSTQNLKTLKTFGAPRPYSSSG----PSPFALAVVKRSQSFSKERTESPS 1046 P P V+T L T P P SS+ PSP + A + T SPS Sbjct: 972 SPPPCPPVLTVATPPPPLLPTVPLPAPSSSASPHPCPSPLSNATAQSPLPILSP-TVSPS 1030 Query: 1047 ASALVQPPANTEEGKTHSVNKFVDIPQLGVSDKENNSAHNEQNSQIPTPTDGPSFTVMR- 1105 S + PP + S + S+ + +S P P S V Sbjct: 1031 PSPI--PPVEPLMSAASPGPPTLSSSSSSSSSSSSFSSSSSSSSPSPPPLSAISSVVSSG 1088 Query: 1106 ---QSSLTFQSSDPEQMRQSLLTAIRSGEAAAK 1135 ++SL S E++ L ++AA+ Sbjct: 1089 DNLEASLPMISFKQEELENEGLKPREEPQSAAE 1121 >gi|20336258 retinoblastoma protein-binding zinc finger protein isoform a [Homo sapiens] Length = 1718 Score = 45.1 bits (105), Expect = 4e-04 Identities = 69/296 (23%), Positives = 109/296 (36%), Gaps = 36/296 (12%) Query: 804 KKHTHEN----VKET-AIQTEDSAISESPEEPLPNLKPKPNLRTEHQVPSSVSSPDDAMV 858 KKH ++ KE+ ++Q SA+ + +P + K L + + V +P D Sbjct: 854 KKHCSDSEGKEFKESHSVQPTCSAVKK--RKPTTCMLQKVLLNEYNGIDLPVENPADGTR 911 Query: 859 SP-----LKPAPKMTRDTGTAPFAPNLEEINNILESKFKSRASNAQAKPSSFFLQMQKRV 913 SP L+ P G+ AP +E ++ PSS LQ Sbjct: 912 SPSPCKSLEAQPDPDLGPGSGFPAPTVESTPDVC--------------PSSPALQTPSLS 957 Query: 914 SGHYVTSAAAKSVHAAPNPAPKELTNKEAERDMLPSPEQTLSPLSKMPHSVPQPLVEKTD 973 SG + + ++P P P LT +LP+ S PH P PL T Sbjct: 958 SGQ-LPPLLIPTDPSSPPPCPPVLTVATPPPPLLPTVPLPAPSSSASPHPCPSPLSNAT- 1015 Query: 974 DDVIGQAPAEASPPPIAPKPVTIPASQVSTQNLKTLKTFGAPRPYSSSGPSPFALAVVKR 1033 Q+P P ++P P IP + L + + G P SSS S + + Sbjct: 1016 ----AQSPLPILSPTVSPSPSPIP----PVEPLMSAASPGPPTLSSSSSSSSSSSSFSSS 1067 Query: 1034 SQSFSKERTESPSASALVQPPANTEEGKTHSVNKFVDIPQLGVSDKENNSAHNEQN 1089 S S S + S++V N E K ++ G+ +E + EQ+ Sbjct: 1068 SSSSSPSPPPLSAISSVVSSGDNLEASLPMISFKQEELENEGLKPREEPQSAAEQD 1123 Score = 30.8 bits (68), Expect = 7.9 Identities = 46/213 (21%), Positives = 72/213 (33%), Gaps = 11/213 (5%) Query: 931 NPAPKELTNKEAERDMLPSPEQTLSPLSKMPHSVPQPLVEKTDDDVIGQAPAEASPPPIA 990 +P+P + + + D+ P + P P +T GQ P P + Sbjct: 912 SPSPCKSLEAQPDPDLGPGSGFPAPTVESTPDVCPSSPALQTPSLSSGQLPPLLIPTDPS 971 Query: 991 PKPVTIPASQVSTQNLKTLKTFGAPRPYSSSG----PSPFALAVVKRSQSFSKERTESPS 1046 P P V+T L T P P SS+ PSP + A + T SPS Sbjct: 972 SPPPCPPVLTVATPPPPLLPTVPLPAPSSSASPHPCPSPLSNATAQSPLPILSP-TVSPS 1030 Query: 1047 ASALVQPPANTEEGKTHSVNKFVDIPQLGVSDKENNSAHNEQNSQIPTPTDGPSFTVMR- 1105 S + PP + S + S+ + +S P P S V Sbjct: 1031 PSPI--PPVEPLMSAASPGPPTLSSSSSSSSSSSSFSSSSSSSSPSPPPLSAISSVVSSG 1088 Query: 1106 ---QSSLTFQSSDPEQMRQSLLTAIRSGEAAAK 1135 ++SL S E++ L ++AA+ Sbjct: 1089 DNLEASLPMISFKQEELENEGLKPREEPQSAAE 1121 >gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens] Length = 1020 Score = 44.7 bits (104), Expect = 5e-04 Identities = 63/311 (20%), Positives = 110/311 (35%), Gaps = 22/311 (7%) Query: 794 KDDQDMHALGKKHTHENVKETA-IQTEDSAISESPEEPLPNLKPKPNLRTEHQVPSSVSS 852 K++ A K E K A +++ + A S + EE K K + E + P S Sbjct: 609 KEEAKSPAEAKSPVKEEAKSPAEVKSPEKAKSPTKEEAKSPEKAKSPEKEEAKSPEKAKS 668 Query: 853 PDDAMVSPLKPAPKMTRDTGTAPF---APNLEEINNILESK--FKSRASNAQAKPSSFFL 907 P A + A + +P +P EE + ++K K A + + S Sbjct: 669 PVKAEAKSPEKAKSPVKAEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKSPEKAKSPVKE 728 Query: 908 QMQKRVSGHYVTSAAAKSVHAAPNPAPKELTNKEAERDMLPSPEQTLSPLSKMPHSVPQP 967 + + AKS A +P + + ++ P+ E+ SP K P P Sbjct: 729 EAKTPEKAKSPVKEEAKSPEKAKSPEKAKTLDVKSPEAKTPAKEEARSPADKFPEKAKSP 788 Query: 968 LVEKTDDDVIGQAPAE---ASPPPIAPKPVTIPASQVSTQNLKTLKTFGAPRPYSSSGPS 1024 + E+ ++P + +P PK + + + + +K P+ Sbjct: 789 VKEEVKSPEKAKSPLKEDAKAPEKEIPKKEEVKSPVKEEEKPQEVKVKEPPK----KAEE 844 Query: 1025 PFALAVVKRSQSFSKERTESPSASALVQPPANTEEGKTHSVNKFVDIPQLGVSDKENNSA 1084 A A K + ++ E+P A P EE K +V K + S E Sbjct: 845 EKAPATPKTEEKKDSKKEEAPKKEA---PKPKVEEKKEPAVEKPKE------SKVEAKKE 895 Query: 1085 HNEQNSQIPTP 1095 E ++PTP Sbjct: 896 EAEDKKKVPTP 906 Score = 39.3 bits (90), Expect = 0.022 Identities = 58/261 (22%), Positives = 95/261 (36%), Gaps = 23/261 (8%) Query: 888 ESKFKSRASNAQAKPSSFFLQMQKRVSGHYVTSAAAKSVHAAPNPAPKELTNKEAERDML 947 E + KS + A P + + V + A AKS +P E+ K E+ Sbjct: 498 EEETKSPPAEEAASPEK---EAKSPVKEEAKSPAEAKSPEKEEAKSPAEV--KSPEKAKS 552 Query: 948 PSPEQTLSPL---------SKMPHSVPQPLVEKTDDDVIGQAPAEASPPPIAPKPV---- 994 P+ E+ SP +K P V P K+ ++PAEA P A PV Sbjct: 553 PAKEEAKSPPEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPAEAKSPEKAKSPVKEEA 612 Query: 995 TIPASQVSTQNLKTLKTFGAPRPYSSSGPSPFALAVVKRSQSFSKERTESP-SASALVQP 1053 PA S + P + P+ ++++S KE +SP A + V+ Sbjct: 613 KSPAEAKSPVKEEAKSPAEVKSPEKAKSPTKEEAKSPEKAKSPEKEEAKSPEKAKSPVKA 672 Query: 1054 PANTEEGKTHSVNKFVDIPQLGVSD-KENNSAHNEQNSQIPTPTDGPSFTVMRQSSLTFQ 1112 A + E V P+ S KE + + S + P +S + + Sbjct: 673 EAKSPEKAKSPVKAEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKSPE---KAKSPVKEE 729 Query: 1113 SSDPEQMRQSLLTAIRSGEAA 1133 + PE+ + + +S E A Sbjct: 730 AKTPEKAKSPVKEEAKSPEKA 750 Score = 33.9 bits (76), Expect = 0.93 Identities = 95/509 (18%), Positives = 166/509 (32%), Gaps = 85/509 (16%) Query: 361 KRKAPSPPSKIPPHQSDENSRVTALQPVDGVPPDSASEANSPEELSSPETFHPGLSSQEQ 420 K +A SP P + + S P P + EA SP E SPE +E+ Sbjct: 521 KEEAKSPAEAKSPEKEEAKSPAEVKSPEKAKSP-AKEEAKSPPEAKSPE--------KEE 571 Query: 421 CTAPKLMEETSVFECPGTPEAAITSLTSGISSDYSLEEIDEKEELSEVPKVEAENISPKS 480 +P ++ + P EA + S + + K V+ E SP Sbjct: 572 AKSPAEVKSPEKAKSPAKEEAKSPAEAKSPEKAKSPVKEEAKSPAEAKSPVKEEAKSPAE 631 Query: 481 QDIPFVSTDIINTLKNDPDSALGNGSGEFSQNSMEEKQETKSTDGQEPHSVVYDTSNGKK 540 P + P+ A EK+E KS + + V + + +K Sbjct: 632 VKSPEKAKSPTKEEAKSPEKA-----------KSPEKEEAKSPE-KAKSPVKAEAKSPEK 679 Query: 541 VVDSIRNLKSLGPNQENVQNEIIVYPENTEDNMKNGVKKTEINVEGVAKNNNIDMEVERP 600 ++ ++ E PE + +K K E V + + + P Sbjct: 680 AKSPVKAEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKTPEKAKSP 739 Query: 601 SNSEAHETDTAISYKENHLAASSVPDQKLNQPSAEKTKDAAIQTTPSCNSFDGKHQDHNL 660 EA + A S ++ P+ K P+ E+ + A + F K Sbjct: 740 VKEEAKSPEKAKSPEKAKTLDVKSPEAK--TPAKEEARSPA-------DKFPEK------ 784 Query: 661 SDSKVEECVQTSNNNIS-TQHSCLSSQDSVNTSREFRSQGTLIIHSEDPLTVKDPICAHG 719 + S V+E V++ S + + + + E +S + E P VK Sbjct: 785 AKSPVKEEVKSPEKAKSPLKEDAKAPEKEIPKKEEVKSP---VKEEEKPQEVKVK----- 836 Query: 720 NDDLLPPVDRIDKNSTASYLKNYPLYRQDYNPKPKPSNEITREYIPKIGMTTYKIVPPKS 779 PP ++ + A+ PK + + +E PK K+ K Sbjct: 837 ----EPPKKAEEEKAPAT-------------PKTEEKKDSKKEEAPKKEAPKPKVEEKKE 879 Query: 780 LEISKDWQSETIEYKDDQDMHALGKKHTHENVKETAIQTEDSAISESPEEPLP-NLKPKP 838 + K +S+ K+ + ED +PE+ P ++ K Sbjct: 880 PAVEKPKESKVEAKKE---------------------EAEDKKKVPTPEKEAPAKVEVKE 918 Query: 839 NLRTEHQVPSSVSSPDDAMV-SPLKPAPK 866 + + + + + PDDA P KPA K Sbjct: 919 DAKPKEKTEVAKKEPDDAKAKEPSKPAEK 947 >gi|132626688 mediator of DNA-damage checkpoint 1 [Homo sapiens] Length = 2089 Score = 44.3 bits (103), Expect = 7e-04 Identities = 51/216 (23%), Positives = 80/216 (37%), Gaps = 29/216 (13%) Query: 827 PEEPLPNLKPKPNLRTEHQVPSSVSSPDDAMVSPLKPAPKMTRDTGT--APFAPNLEEIN 884 PE P P KP + +H P + SP ++ +KP + TR G+ AP AP E+ Sbjct: 1043 PEAPAPPQKPLNSQSQKHLAPPPLLSP---LLPSIKPTVRKTRQDGSQEAPEAPLSSELE 1099 Query: 885 NI-LESKFKSRASNAQAKPSSFFLQMQKRVSGHYVTSAAAKSVHAAPNPAPKELTNKEAE 943 + K ++R S+ F H TS A + A + TN+ + Sbjct: 1100 PFHPKPKIRTRKSSRMTP----FPATSAAPEPHPSTSTAQPVTPKPTSQATRSRTNRSSV 1155 Query: 944 RDMLPSPEQTLSPLSKMPHSVPQPLVE----------------KTDDDVIGQAPAEASPP 987 + P P +P + S QP+ KT + V+ A E P Sbjct: 1156 K--TPEPVVPTAPELQPSTSTDQPVTSEPTSQVTRGRKSRSSVKTPETVVPTA-LELQPS 1212 Query: 988 PIAPKPVTIPASQVSTQNLKTLKTFGAPRPYSSSGP 1023 +PVT + +T+ K + P P + P Sbjct: 1213 TSTDRPVTSEPTSQATRGRKNRSSVKTPEPVVPTAP 1248 Score = 36.6 bits (83), Expect = 0.14 Identities = 50/222 (22%), Positives = 78/222 (35%), Gaps = 13/222 (5%) Query: 810 NVKETAIQTEDSAISESPEEPLPN----LKPKPNLRTEHQVPSSVSSPDDAMVSPLKPAP 865 ++K T +T E+PE PL + PKP +RT SS +P A + +P P Sbjct: 1073 SIKPTVRKTRQDGSQEAPEAPLSSELEPFHPKPKIRTR---KSSRMTPFPATSAAPEPHP 1129 Query: 866 KMTRDTGTAPFAPNLEEINNILESKFKSR----ASNAQAKPSSFFLQMQKRVSGHYVTSA 921 + P + + S K+ + + +PS+ Q VT Sbjct: 1130 STSTAQPVTPKPTSQATRSRTNRSSVKTPEPVVPTAPELQPSTSTDQPVTSEPTSQVT-R 1188 Query: 922 AAKSVHAAPNPAPKELTNKEAERDMLPSPEQTLSPLSKMPHSVPQPLVEKTDDDVIGQAP 981 KS + P T E + T P S+ KT + V+ AP Sbjct: 1189 GRKSRSSVKTPETVVPTALELQPSTSTDRPVTSEPTSQATRGRKNRSSVKTPEPVVPTAP 1248 Query: 982 AEASPPPIAPKPVTIPASQVSTQNLKTLKTFGAPRPYSSSGP 1023 E P +PVT + +T+ K + P P + P Sbjct: 1249 -ELQPSTSTDQPVTSEPTYQATRGRKNRSSVKTPEPVVPTAP 1289 >gi|239508790 PREDICTED: hypothetical protein, partial [Homo sapiens] Length = 490 Score = 43.9 bits (102), Expect = 9e-04 Identities = 55/235 (23%), Positives = 85/235 (36%), Gaps = 42/235 (17%) Query: 273 SNTISKPYISNTLPSDAPKKRRAPLPPMPASQSVPQDLAHIQERPASCIVKSMSVDETDK 332 S+ S P +LPSD P P PP VP L+ + P+ S Sbjct: 222 SDVPSPPSDVPSLPSDVPSLSGVPSPP----SDVPSLLSGVPSPPSDISPPSDVPSLLSD 277 Query: 333 SPCEAGRVRAGSLQLSSMSAGNSSLRRTKRKAPSPPSKIPPHQSDENSRVTALQPVDGVP 392 P V + LS + + S + PSPPS +P SD + + GVP Sbjct: 278 VPSLPSDVPS---LLSGVPSPPSDVPSLLSDVPSPPSDVPSPPSD-------IPLLSGVP 327 Query: 393 PDSASEANSPEELSSPETFHPGLSSQEQCTAPKLMEETSVFECPGTPEAAITSLTSG--- 449 + + P ++ SP + P LS P + + + +P + + SL Sbjct: 328 SPPSDVPSPPSDVPSPPSDVPLLSG-----VPSPLSDVPLLSGVPSPPSDVPSLLMSPHR 382 Query: 450 -ISSDYSLEEIDEKEELSEVPKVEAENISPKSQDIPFVSTDIINTLKNDPDSALG 503 + S YSL +SP D+P + +D+ + L P S G Sbjct: 383 LLMSHYSL-------------------VSPHRLDVPSLLSDVPSLLSGVPSSPSG 418 Score = 38.9 bits (89), Expect = 0.029 Identities = 62/255 (24%), Positives = 96/255 (37%), Gaps = 33/255 (12%) Query: 257 APATPLVNKHRPTFTRSNTISKPYISNTLPSDAPKKRRAPLPPMPASQSVPQ-----DLA 311 +P PLV+ H P + P+ S P +P PL S P L Sbjct: 59 SPHFPLVSPHHP-------LMSPHYSLVSPQYSPVSPHCPLVSPHYSLVSPHRPLVSPLL 111 Query: 312 HIQERPASCIVKSMSVDETDKSPCEAGRVRAGSLQLSSMSAGNSSLRRTKRKAPSPPSKI 371 P S + +S + S + SL LS + + S + PSPPS + Sbjct: 112 SGVPSPPSDVPSLLSGVPSLPSDVSSPPSDVPSL-LSDVPSLLSGVPSPPSDVPSPPSDV 170 Query: 372 PPHQSDENSRVTALQPVDGVPPDSASEANSPEELSSPETFHPGLSSQEQCTAPKLMEETS 431 P SD S ++ GVP + + P ++ SP + P LS P + Sbjct: 171 PSPPSDVPSLLS------GVPSPPSDVPSPPSDVPSPPSDVPLLSD-----VPSPPSDVP 219 Query: 432 VFECPGTPEAAITSLTSGISSDYSLEE--IDEKEELSEVPKVEAENISPKS------QDI 483 + +P + + SL S + S + D LS VP ++ ISP S D+ Sbjct: 220 LLSDVPSPPSDVPSLPSDVPSLSGVPSPPSDVPSLLSGVPSPPSD-ISPPSDVPSLLSDV 278 Query: 484 PFVSTDIINTLKNDP 498 P + +D+ + L P Sbjct: 279 PSLPSDVPSLLSGVP 293 >gi|222352122 hypothetical protein LOC284297 [Homo sapiens] Length = 1573 Score = 43.5 bits (101), Expect = 0.001 Identities = 75/348 (21%), Positives = 109/348 (31%), Gaps = 46/348 (13%) Query: 777 PKSLEISKDWQSETIEYKDDQDMHALGKKHTHENVKETAIQTEDSAISESPE---EPLPN 833 PK L SE + + + T ++ T + S S SP+ P P Sbjct: 1095 PKELTSDPSTPSEVTSLSPTSEQ--VPESDTTPDLDTTPYSSTVSEYSRSPDPSPSPHPT 1152 Query: 834 LKPKPNLRTEHQVPSSVSSPDDAMVSPLKPAPKMTRDTGTAPFAPNLEEINNILESKFKS 893 P P + + P + +P P P P T T + + + + Sbjct: 1153 TTPDPTMAPD---PITTLNPTVTPHFPTTPHPTTTPHPTTITHSTMIPDPTTTPQPFTTI 1209 Query: 894 RASNAQAKPSSF---FLQMQKRVSGHYVTSAAAKSVHAAPNPAPKELTNKEAERD--MLP 948 S P++ F MQ + H T H P P +T+ D P Sbjct: 1210 THSTMIPDPTTTPQPFTTMQPTTTPHSTTP------HPTTTPHPTTITHSTMIPDPTTTP 1263 Query: 949 SPEQTLSPLSKMPHSVPQPLVEKTDDDVIGQAPAEASPPPIAPKPVTIPASQVSTQNLKT 1008 P T+ P + MPH P T P P + P P T P + T Sbjct: 1264 QPFTTMQPTT-MPHPTTTPHPTTTPHPTTTPHPTTTPHPTMTPDPTTTPYPTTTPDPTTT 1322 Query: 1009 LKTFGAPRPYSSSGPSPFALAVVKRSQSFSKERTESPSASALVQPPANTEEGKTHSVNKF 1068 P P + S + V S E + SP+ + V+P + Sbjct: 1323 ------PHPTTPDPSSTPVITTVSLPTSLGTELS-SPTLAPTVKPSLH------------ 1363 Query: 1069 VDIPQLGVSDKENNSAHNEQNSQIPTPTDGPSFTVMRQSSLTFQSSDP 1116 PQL + A + SQIPT P+ S T S DP Sbjct: 1364 ---PQLTFTAP----APHTSTSQIPTLEPSPALESSPSRSSTATSMDP 1404 Score = 38.1 bits (87), Expect = 0.049 Identities = 71/347 (20%), Positives = 117/347 (33%), Gaps = 48/347 (13%) Query: 801 ALGKKHTHENVKETAIQTEDSAISESPEEPLPNLKPKPNLRTEHQV-----PSSVSSPDD 855 AL + E +A+ +E A S++P+ P P P RT + ++S+PD Sbjct: 1021 ALTSDSSRELTPHSALTSE--ATSDAPDTSPPT--PDPASRTNPDLILTSPDFALSTPDS 1076 Query: 856 AMVSPLKPAPKMTRDTGTAPFAPNLEEINNILESKFKSRASNAQAKPSSFFLQMQKRVSG 915 ++V L P P T P P + S+ S + ++ P S Sbjct: 1077 SVVPALTPEPSPT----PLPTLPKELTSDPSTPSEVTSLSPTSEQVPESDTTPDLDTTPY 1132 Query: 916 HYVTSAAAKSVHAAPNPAPKELTNKEAERDMLPSPEQTLSPLSKMPHSVPQPLVEKTDDD 975 S ++S P+P+P + M P P TL+P + PH P T Sbjct: 1133 SSTVSEYSRS----PDPSPSPHPTTTPDPTMAPDPITTLNP-TVTPHFPTTPHPTTTPHP 1187 Query: 976 VIGQAPAEASPPPIAPKPVT-------IPASQVSTQNLKTLKTFGAPR---PYSSSGPSP 1025 P P+P T IP + Q T++ P P+ ++ P P Sbjct: 1188 TTITHSTMIPDPTTTPQPFTTITHSTMIPDPTTTPQPFTTMQPTTTPHSTTPHPTTTPHP 1247 Query: 1026 FALAVVKRSQSFSKERTESPSASALVQP-----PANTEEGKTHSVNKFVDIPQLGVSDKE 1080 + + + T +P +QP P T T P + Sbjct: 1248 TTIT----HSTMIPDPTTTPQPFTTMQPTTMPHPTTTPHPTT--------TPHPTTTPHP 1295 Query: 1081 NNSAHNEQNSQIPTPTDGPSFTVMRQSSLTFQSSDPEQMRQSLLTAI 1127 + H + P PT P T + T + P+ ++T + Sbjct: 1296 TTTPH---PTMTPDPTTTPYPTTTPDPTTTPHPTTPDPSSTPVITTV 1339 Score = 32.7 bits (73), Expect = 2.1 Identities = 57/288 (19%), Positives = 90/288 (31%), Gaps = 61/288 (21%) Query: 826 SPEEPLPNLKPKPNLRTEHQVPSSVSSPDDAMVSPLKPAPKMTRDTGTAPFAPNLEEINN 885 SP +P P +P T P+ P SP P P +T D+ + P+ + Sbjct: 984 SPRKPWPERRPPRPAATRTAPPTPSPGPS---ASPGPPGPALTSDS-SRELTPH-----S 1034 Query: 886 ILESKFKSRASNAQAKPSSFFLQMQKRVSGHYVTSAAAKSVHAAPNPAPKELTNKEAERD 945 L S+ S A + + P P P TN + Sbjct: 1035 ALTSEATSDAPDT-----------------------------SPPTPDPASRTNPDL--- 1062 Query: 946 MLPSPEQTLSPLSKMPHSVPQPLVEKTDDDVIGQAPAEASPPPIAPKPVTIPASQVSTQN 1005 +L SP+ LS D V+ E SP P+ P + + + Sbjct: 1063 ILTSPDFALST---------------PDSSVVPALTPEPSPTPLPTLPKELTSDPSTPSE 1107 Query: 1006 LKTLKTFGAPRPYSSSGPSPFALAVVKRSQSFSKERTESPSASALVQPPANTEEGKTHSV 1065 + +L P S + P +S+ SPS P ++ Sbjct: 1108 VTSLSPTSEQVPESDTTPDLDTTPYSSTVSEYSRSPDPSPSPHPTTTPDPTMAPDPITTL 1167 Query: 1066 NKFVDIPQLGVSDKENNSAHN---EQNSQIPTPTDGPS-FTVMRQSSL 1109 N V P + + H ++ IP PT P FT + S++ Sbjct: 1168 NPTV-TPHFPTTPHPTTTPHPTTITHSTMIPDPTTTPQPFTTITHSTM 1214 >gi|237757326 synaptojanin 1 isoform d [Homo sapiens] Length = 1526 Score = 43.5 bits (101), Expect = 0.001 Identities = 65/296 (21%), Positives = 97/296 (32%), Gaps = 50/296 (16%) Query: 819 EDSAISESPEEPLPNLKPKPNLRTEHQVPSSVSSPDDAMVSPLKPAPKMTRD-------- 870 + S I P PLP P L + P +P P +P P R Sbjct: 1077 QSSPIDAQPATPLPQKDPAQPLEPKRPPPPRPVAPPTRPAPPQRPPPPSGRSQPSPQAGL 1136 Query: 871 -----TGTAPFAPNLEEINNILES-KFKSRASNAQAKPSSFFLQMQKRVSGHYVTSAAAK 924 G + P + ++ + + +RAS + P S TS +K Sbjct: 1137 AGPGPAGYSTARPTIPPRAGVISAPQSHARASAGRLTPES-----------QSKTSETSK 1185 Query: 925 SVHAAPNPAPKELTNKEAERDMLPSPEQTL-SPL----SKMPHSVPQPLVEKTDDDVIGQ 979 P P + + LP P Q L PL + MP S PQP +E Sbjct: 1186 GSTFLPEPLKPQAA--FPPQSSLPPPAQRLQEPLVPVAAPMPQSGPQPNLE--------- 1234 Query: 980 APAEASPPPIAPKPVTIPASQVSTQNLKTLKTFGAPRPYSSSGPSPF------ALAVVKR 1033 PPP + ++P+ S +KT R S PF LAV K Sbjct: 1235 --TPPQPPPRSRSSHSLPSEASSQPQVKTNGISDGKRE-SPLKIDPFEDLSFNLLAVSKA 1291 Query: 1034 SQSFSKERTESPSASALVQPPANTEEGKTHSVNKFVDIPQLGVSDKENNSAHNEQN 1089 S +P L+Q P+ T+ SV+ +P + + + + N Sbjct: 1292 QLSVQTSPVPTPDPKRLIQLPSATQSNVLSSVSCMPTMPPIPARSQSQENMRSSPN 1347 >gi|118600981 jumonji domain containing 1C isoform a [Homo sapiens] Length = 2540 Score = 43.1 bits (100), Expect = 0.002 Identities = 87/434 (20%), Positives = 160/434 (36%), Gaps = 58/434 (13%) Query: 471 VEAENISPKSQDIPFVSTDIINTLKNDPDSALGNGSGEFSQNSMEEKQETKSTDGQEPHS 530 +E +N+ P + F+ + + LK + +QN P Sbjct: 228 LEPQNVDPSMVQMTFLDDVVHSLLKGENIGITSRRRSRANQNVNAVHSHYTRAQANSPRP 287 Query: 531 VVYDTSN-GKKVVDSIRNLKSLGPNQENVQNEIIVYPENTEDNMKNGVKKTEINVEGVAK 589 + + K+ + +S+ PN+ + I E ++ + + + E N +G K Sbjct: 288 AMNSQAAVPKQNTHQQQQQRSIRPNKRKGSDSSIPDEEKMKEEKYDYISRGE-NPKGKNK 346 Query: 590 N----NNIDMEVERPSNSEAHETDTAISYKENHLAASSVPDQKLNQPSAEKTKDAAIQT- 644 + E E+ N + TD + E+ + +S ++++ S+E+ + ++ Sbjct: 347 HLMNKRRKPEEDEKKLNMKRLRTDNVSDFSESSDSENS--NKRIIDNSSEQKPENELKNK 404 Query: 645 -TPSCNSFDGKHQDHNLSDSKVEECVQTSNNNIST--QHSCLSSQDSVNTSREFRSQGTL 701 T N +GK ++ + + + Q + I +H + SV+T + Q + Sbjct: 405 NTSKINGEEGKPHNNEKAGEETLKNSQPPWDQIQEDKKHEEAEKRKSVDT----QLQEDM 460 Query: 702 IIHSEDPLTVKDPICAHGNDDLLPPVDRIDKNSTASYLKNYPLYRQDYNPKPKPSNEIT- 760 IIHS + TV D H ++DLLP +DK T L + P PK +IT Sbjct: 461 IIHSSEQSTVSD----HNSNDLLPQECNMDKTHTMELLPKEKFVSRP--PTPKCVIDITN 514 Query: 761 --------------------REYIPKIGMTTYKIVPPKSLEISK-----DWQSETIEYKD 795 ++ P + + + I K LE +K W S+ ++ Sbjct: 515 DTNLEKVAQENSSTFGLQTLQKMDPNVSDSKHSIANAKFLETAKKDSDQSWVSDVVKVDL 574 Query: 796 DQDM---HALGKKHTH-ENVKETAIQTEDSAISESPEEPLPNLKPKP-----NLRTEHQV 846 Q + G H + E K + + SA+S E+ L P P L T Sbjct: 575 TQSSVTNASSGNDHLNMEKEKYVSYISPLSAVSVM-EDKLHKRSPPPETIKSKLNTSVDT 633 Query: 847 PSSVSSPDDAMVSP 860 SSP +V P Sbjct: 634 HKIKSSPSPEVVKP 647 >gi|68342036 jumonji domain containing 1C isoform b [Homo sapiens] Length = 2303 Score = 43.1 bits (100), Expect = 0.002 Identities = 87/434 (20%), Positives = 160/434 (36%), Gaps = 58/434 (13%) Query: 471 VEAENISPKSQDIPFVSTDIINTLKNDPDSALGNGSGEFSQNSMEEKQETKSTDGQEPHS 530 +E +N+ P + F+ + + LK + +QN P Sbjct: 9 LEPQNVDPSMVQMTFLDDVVHSLLKGENIGITSRRRSRANQNVNAVHSHYTRAQANSPRP 68 Query: 531 VVYDTSN-GKKVVDSIRNLKSLGPNQENVQNEIIVYPENTEDNMKNGVKKTEINVEGVAK 589 + + K+ + +S+ PN+ + I E ++ + + + E N +G K Sbjct: 69 AMNSQAAVPKQNTHQQQQQRSIRPNKRKGSDSSIPDEEKMKEEKYDYISRGE-NPKGKNK 127 Query: 590 N----NNIDMEVERPSNSEAHETDTAISYKENHLAASSVPDQKLNQPSAEKTKDAAIQT- 644 + E E+ N + TD + E+ + +S ++++ S+E+ + ++ Sbjct: 128 HLMNKRRKPEEDEKKLNMKRLRTDNVSDFSESSDSENS--NKRIIDNSSEQKPENELKNK 185 Query: 645 -TPSCNSFDGKHQDHNLSDSKVEECVQTSNNNIST--QHSCLSSQDSVNTSREFRSQGTL 701 T N +GK ++ + + + Q + I +H + SV+T + Q + Sbjct: 186 NTSKINGEEGKPHNNEKAGEETLKNSQPPWDQIQEDKKHEEAEKRKSVDT----QLQEDM 241 Query: 702 IIHSEDPLTVKDPICAHGNDDLLPPVDRIDKNSTASYLKNYPLYRQDYNPKPKPSNEIT- 760 IIHS + TV D H ++DLLP +DK T L + P PK +IT Sbjct: 242 IIHSSEQSTVSD----HNSNDLLPQECNMDKTHTMELLPKEKFVSRP--PTPKCVIDITN 295 Query: 761 --------------------REYIPKIGMTTYKIVPPKSLEISK-----DWQSETIEYKD 795 ++ P + + + I K LE +K W S+ ++ Sbjct: 296 DTNLEKVAQENSSTFGLQTLQKMDPNVSDSKHSIANAKFLETAKKDSDQSWVSDVVKVDL 355 Query: 796 DQDM---HALGKKHTH-ENVKETAIQTEDSAISESPEEPLPNLKPKP-----NLRTEHQV 846 Q + G H + E K + + SA+S E+ L P P L T Sbjct: 356 TQSSVTNASSGNDHLNMEKEKYVSYISPLSAVSVM-EDKLHKRSPPPETIKSKLNTSVDT 414 Query: 847 PSSVSSPDDAMVSP 860 SSP +V P Sbjct: 415 HKIKSSPSPEVVKP 428 >gi|7656879 ALL1 fused gene from 5q31 [Homo sapiens] Length = 1163 Score = 43.1 bits (100), Expect = 0.002 Identities = 121/678 (17%), Positives = 233/678 (34%), Gaps = 109/678 (16%) Query: 338 GRVRAGSLQLSSMSAGNSSLRRTKRKAPSPPSKIPPHQSDENSRV---TALQPVDGVPPD 394 G+ +A S SS S + + +K S + P D SRV + PP Sbjct: 182 GKPQAVSSLNSSHSRSHGNDHHSKEHQRSKSPRDPDANWDSPSRVPFSSGQHSTQSFPPS 241 Query: 395 SASEANSPEELSSPETFHPGLSSQEQCTAPKLMEE--------TSVFECPGTPEAAITSL 446 S++NS L P + + QE PKL E S+ E + +A +T L Sbjct: 242 LMSKSNSM--LQKPTAYVRPMDGQESME-PKLSSEHYSSQSHGNSMTELKPSSKAHLTKL 298 Query: 447 T-------SGISSDYS-LEEIDEKEELSEVPKVEAENISPKSQDIPFVSTDIINTLKNDP 498 + S D S ++EI ++ S P + A + K++ F P Sbjct: 299 KIPSQPLDASASGDVSCVDEILKEMTHSWPPPLTAIHTPCKTEPSKF------------P 346 Query: 499 DSALGNGSGEFSQNSMEEKQETKSTDGQEPHSVVYDT--------SNGKKVVDSIRNLKS 550 + F + +K+++G + S++ D S+G++ D + Sbjct: 347 FPTKESQQSNFGTGEQKRYNPSKTSNGHQSKSMLKDDLKLSSSEDSDGEQDCDKTMPRST 406 Query: 551 LGPNQENVQNEIIVYPENTEDNMKNGVKKTEINVEGVAKNNNIDMEVERPSNSEAHETDT 610 G N E + + +D+ + ++ + +++++ D E PS S + E + Sbjct: 407 PGSNSEPSHHNSEGADNSRDDSSSHSGSESSSGSDSESESSSSDSEANEPSQSASPEPEP 466 Query: 611 AISYK-----------ENHLAASSVPDQKLNQPSAEKTKDAAIQTTPSCNSFDGKHQDHN 659 + K + ++ +S D + K + T S G + + Sbjct: 467 PPTNKWQLDNWLNKVNPHKVSPASSVDSNIPSSQGYKKEGREQGTGNSYTDTSGPKETSS 526 Query: 660 LSDSKVEECVQTSNNNISTQHSCLSSQDSVNTSREF--------------RSQGTLIIHS 705 + + + +Q + + + + DS R +G L I S Sbjct: 527 ATPGRDSKTIQKGSESGRGRQKSPAQSDSTTQRRTVGKKQPKKAEKAAAEEPRGGLKIES 586 Query: 706 EDPLTVKDPICAHGNDDLLPPVDRIDKNSTASYLKNYPLYRQDYNPKPKPSNEITREYIP 765 E P+ + + + ++ A+ P +++ P+P+ E Sbjct: 587 ETPVDLASSMPS-------------SRHKAATKGSRKPNIKKESKSSPRPTAE------K 627 Query: 766 KIGMTTYKIVPPKSLEISKDWQSETIEYKDDQDMHALGKKHTHEN---VKETAIQTEDSA 822 K +T K I D S + + + K+ N VK ++++ EDS Sbjct: 628 KKYKSTSKSSQKSREIIETDTSSSDSDESESLPPSSQTPKYPESNRTPVKPSSVEEEDSF 687 Query: 823 ISESPEEPLPNLKPKPNLRTEHQVPSSVSSPDDAMVSPLKPAPKMTRDTGTAPF---APN 879 + P+ E ++ S +S PDD +K + P+ P Sbjct: 688 FRQRMFSPM----------EEKELLSPLSEPDDRYPLIVKIDLNLLTRIPGKPYKETEPP 737 Query: 880 LEEINNILESKFKSRASNAQAKPSSFFLQMQKRVSGHYVTSAAAKSVHAAPNPAPKELTN 939 E N+ E + A K S+ + K + + + + K +N Sbjct: 738 KGEKKNVPEKHTREAQKQASEKVSNKGKRKHKNEDDNRASESKKPKTEDKNSAGHKPSSN 797 Query: 940 KEA-------ERDMLPSP 950 +E+ E+D+LPSP Sbjct: 798 RESSKQSAAKEKDLLPSP 815 >gi|189181724 proteoglycan 4 isoform D [Homo sapiens] Length = 1270 Score = 42.7 bits (99), Expect = 0.002 Identities = 66/327 (20%), Positives = 107/327 (32%), Gaps = 35/327 (10%) Query: 708 PLTVKDPICAHGNDDLLPPVDRIDKNSTASYLKNYPLYRQDYNPKP--KPSNEITREYIP 765 P T K+P + P K + K+ P ++ P KP+ +E P Sbjct: 264 PTTTKEPAPTTPKE----PAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAP 319 Query: 766 KIGMTTYKIVPPKSLEISKDWQSETIEYKDDQDMHALGKKHTHENVKETAIQTEDSAISE 825 TT K P + + E + KK KE A T Sbjct: 320 ----TTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPT 375 Query: 826 SPEEPLPNLKPKPNLRTEHQVPSSVSSP-----DDAMVSPLKPAPKMTRDTG-TAPFAPN 879 + +EP P +P T P++ P A +P +P+P T++ T P P Sbjct: 376 TTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPA 435 Query: 880 LEEINNILESKFKSRASNAQAKPSSFFLQMQKRVSGHYVTSAAAKSVHAAPNPAPKELTN 939 + K A +P+ T A + P P + T Sbjct: 436 PTTPKKPAPTTPKEPAPTTPKEPAP------------TTTKKPAPTTPKEPAPTTPKETA 483 Query: 940 KEAERDMLPSPEQTLSPLSKMPHSVPQPLVEKTDDDVIGQAPAEASP-PPIAPKPVTIPA 998 + + P+ + L+P + P+ T +++ P E +P P P P T A Sbjct: 484 PTTPKKLTPTTPEKLAP------TTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKA 537 Query: 999 SQVSTQNLKTLKTFGAPRPYSSSGPSP 1025 + +T T P P + P+P Sbjct: 538 AAPNTPKEPAPTTPKEPAPTTPKEPAP 564 Score = 41.2 bits (95), Expect = 0.006 Identities = 80/390 (20%), Positives = 126/390 (32%), Gaps = 66/390 (16%) Query: 750 NPKPK--PSNEITREYIPKIGMTTY---KIVPPKSLEISKDWQSETIEYKDDQDMHALGK 804 NP+P P+++ ++E + T K + + S D + +T K+ Q + Sbjct: 125 NPRPSLPPNSDTSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSA 184 Query: 805 KH--------------THENVKETAIQTEDSAISESPEEPLPNLKPKPNLRTEHQVPSSV 850 K K A+ T +P+EP +P P+++ Sbjct: 185 KDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEP-------TPTTI 237 Query: 851 SSPDDAMVSPLKPAPKMTRDTGTAPFAPNLEEINNILESKFKSRASNAQAKPSSFFLQMQ 910 S A +P +PAP T+ T P P + K A +P+ Sbjct: 238 KS---APTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAP------ 288 Query: 911 KRVSGHYVTSAAAKSVHAAPNPA----PKELTNKEAERDMLPSPEQTLSPLSKMPHSVPQ 966 T+ +A + P P P T KE P+P P P P Sbjct: 289 -------TTTKSAPTTPKEPAPTTPKKPAPTTPKE------PAPTTPKEPTPTTPKE-PA 334 Query: 967 PLVEKTDDDVIGQAPAEASP-PPIAPKPVTIPASQVSTQNLKTLKTFGAPRPYSSSGPSP 1025 P T + P E +P P P P T +T T P P + P+P Sbjct: 335 P----TTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAP 390 Query: 1026 FALAVVKRSQSFSKERTESPSASALVQP----PANTEE-GKTHSVNKFVDIPQLGVSDKE 1080 K + + +KE + + SA P P T+E T P+ Sbjct: 391 ---TTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTP 447 Query: 1081 NNSAHNEQNSQIPTPTDGPSFTVMRQSSLT 1110 A PT T P+ T ++ + T Sbjct: 448 KEPAPTTPKEPAPTTTKKPAPTTPKEPAPT 477 Score = 39.7 bits (91), Expect = 0.017 Identities = 60/274 (21%), Positives = 97/274 (35%), Gaps = 43/274 (15%) Query: 251 RDQTASAPATPLVNKHRPTFTRSNTISKPYISNTLPSDAPK--KRRAPLPPMPASQSVPQ 308 ++ + P P + PT T+ T S T AP K AP P + + P+ Sbjct: 584 KEPAPTTPKKPAPKELAPTTTKEPT------STTCDKPAPTTPKGTAPTTPKEPAPTTPK 637 Query: 309 DLAHIQERPASCIVKSMSVDETDKSPCE---AGRVRAGSLQLSSMSAGNSSLRRT----- 360 + A + + T K P A G +S ++ + T Sbjct: 638 EPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTP 697 Query: 361 --------KRKAPSPPSKIPPHQSDENSRVTALQPV------DGVPPDSASEA------N 400 K+ AP+ P PP S+ ++ T +P D P+ ++E N Sbjct: 698 KEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALEN 757 Query: 401 SPEELSSPETFHPGLSSQEQCTAPKLMEETSVFECPGTPEAAITSLTSGISSDYSLEEID 460 SP+E P T P + E T K ++T+ + TPE + T+ Sbjct: 758 SPKEPGVPTTKTPAATKPEMTTTAK--DKTTERDLRTTPE----TTTAAPKMTKETATTT 811 Query: 461 EKEELSEVPKVEAENISPKSQD-IPFVSTDIINT 493 EK S++ + S +QD PF T + T Sbjct: 812 EKTTESKITATTTQVTSTTTQDTTPFKITTLKTT 845 Score = 37.0 bits (84), Expect = 0.11 Identities = 53/262 (20%), Positives = 87/262 (33%), Gaps = 27/262 (10%) Query: 807 THENVKETAIQTEDSAISESPEEPLPNLKPKPNLRTEHQVPSSVSSPDDAMVSPLKPAPK 866 T V E + I +SP+E P L +P + P P + KP Sbjct: 719 TTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEPGVPTTKTPAATKPEMT 778 Query: 867 MT-RDTGTAPFAPNLEEINNILESKFKSRASNAQAKPSSFFLQMQKRVSGHYVTSAAAKS 925 T +D T E K A+ + S +V+ Sbjct: 779 TTAKDKTTERDLRTTPETTTAAPKMTKETATTTEKTTESKITATTTQVTSTTTQDTTPFK 838 Query: 926 VHAAPNP--APKELTNKE--AERDMLPSPEQTLSPLSKMPHS---VPQPLVEKTDDDVIG 978 + APK T K+ +++ PE+T P + +S P+P Sbjct: 839 ITTLKTTTLAPKVTTTKKTITTTEIMNKPEETAKPKDRATNSKATTPKP----------- 887 Query: 979 QAPAEASPPPIA-PKPVTIPASQVSTQNLKTLKTFGAPRPYSSSGPSPFALAVVKRSQSF 1037 Q P +A P + KP T+P ++ KT PR +S+ P + + + Sbjct: 888 QKPTKAPKKPTSTKKPKTMP-------RVRKPKTTPTPRKMTSTMPELNPTSRIAEAMLQ 940 Query: 1038 SKERTESPSASALVQPPANTEE 1059 + R S LV+ +E+ Sbjct: 941 TTTRPNQTPNSKLVEVNPKSED 962 Score = 36.2 bits (82), Expect = 0.19 Identities = 39/196 (19%), Positives = 68/196 (34%), Gaps = 6/196 (3%) Query: 247 SKKKRDQTASAPATPLVNKHRPTFTRSNTISKPYISNTLPSDAPKKRRAPLPPMPASQSV 306 +K+ T PA K PT + + P P+ K +P P + + Sbjct: 337 TKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTP----KEPAPTTTKEPSPTTPKEPAPTT 392 Query: 307 PQDLAHIQERPASCIVKSMSVDETDKSPCEAGRVRAGSLQLSSMSAGNSSLRRT-KRKAP 365 + + PA KS + SP + + + + T K AP Sbjct: 393 TKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAP 452 Query: 366 SPPSKIPPHQSDENSRVTALQPVDGVPPDSASEANSPEELSSPETFHPGLSSQEQCTAPK 425 + P + P + + + T +P P ++A ++PE P + T P+ Sbjct: 453 TTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPE 512 Query: 426 LMEETSVFE-CPGTPE 440 + T+ E P TPE Sbjct: 513 ELAPTTPEEPTPTTPE 528 Score = 36.2 bits (82), Expect = 0.19 Identities = 69/315 (21%), Positives = 99/315 (31%), Gaps = 31/315 (9%) Query: 812 KETAIQTEDSAISESPEEPLPNLKPKPNLRTEHQVPSSVSSPDDAMVSPLKPAPKMTRDT 871 KE A T +P+EP P PK T + + + A +P KPAP + Sbjct: 456 KEPAPTTTKKPAPTTPKEPAPTT-PKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEEL 514 Query: 872 G-TAPFAPNLEEINNILESKFKSRASNAQAKPSSFFLQMQKRVSGHYVTSAAAKSVHAAP 930 T P P + K+ A N +P+ + + K A Sbjct: 515 APTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKET-APT 573 Query: 931 NP---APKELTNKEAERDMLPSPEQTLSPLSKMPHSV----PQPLVEKTDDDVIGQAPAE 983 P AP L P+P++ +K P S P P K + PA Sbjct: 574 TPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAP 633 Query: 984 ASPPPIAPKPVTIPASQVSTQNLKTLKTFGAPRPYSSSGPSPFALAVV----KRSQSFSK 1039 +P AP T P T T P P + P+P LA S + K Sbjct: 634 TTPKEPAP---TTPKGTAPT-------TLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDK 683 Query: 1040 ERTESPSASALVQP--PANTEEGKTHSVNKFVDIPQLG-----VSDKENNSAHNEQNSQI 1092 +P +A P PA T K P + KE + H + Sbjct: 684 PAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDEST 743 Query: 1093 PTPTDGPSFTVMRQS 1107 P + P+ + S Sbjct: 744 PELSAEPTPKALENS 758 Score = 35.8 bits (81), Expect = 0.24 Identities = 48/202 (23%), Positives = 73/202 (36%), Gaps = 10/202 (4%) Query: 247 SKKKRDQTASAPATPLVNKHRPTFTR----SNTISKPYISNTLPSDAPKKRRAPLPPMPA 302 +K+ T PA P K PT T+ + T S P PS K AP P Sbjct: 377 TKEPSPTTPKEPA-PTTTKSAPTTTKEPAPTTTKSAPTTPKE-PSPTTTKEPAPTTPKEP 434 Query: 303 SQSVPQDLAHIQER-PASCIVKSMSVDETDKSPCEAGRVRAGSLQLSSMSAGNSSLRRT- 360 + + P+ A + PA K + T K + A + + L T Sbjct: 435 APTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTT 494 Query: 361 -KRKAPSPPSKIPPHQSDENSRVTALQPVDGVPPDSASEANSPEELSSPETFHPGLSSQE 419 ++ AP+ P K P +E + T +P P + A ++P+ P + Sbjct: 495 PEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEP 554 Query: 420 QCTAPKLMEETSVFE-CPGTPE 440 T PK T+ E P TP+ Sbjct: 555 APTTPKEPAPTTPKETAPTTPK 576 Score = 35.8 bits (81), Expect = 0.24 Identities = 58/266 (21%), Positives = 94/266 (35%), Gaps = 37/266 (13%) Query: 257 APATPLVNKHRPTFTRSNTISKPY--ISNTLPSDAPK--KRRAPLPPMPASQSVPQDLAH 312 AP TP + PT T + P T + AP K AP P + + P++ A Sbjct: 507 APTTP--EELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAP 564 Query: 313 IQERPASCIVKSMSVDETDKSPCEAGRVRAGSLQLSSMSAGNSSLRRTKRKAPSPPSKIP 372 + + + T K P + +L+ + + + AP+ P Sbjct: 565 TTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTA 624 Query: 373 PHQSDENSRVTALQPVDGVPPDSA-----------SEANSPEELSSPETFHPGLSSQEQ- 420 P E + T +P P +A + +P+EL+ T P ++ ++ Sbjct: 625 PTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKP 684 Query: 421 -CTAPKLMEETSVFE---------CPGTPEAAITSLTSGISSDYSLEE--------IDEK 462 T PK T+ E P TPE TS +S+ + +E + Sbjct: 685 APTTPKETAPTTPKEPAPTTPKKPAPTTPETP-PPTTSEVSTPTTTKEPTTIHKSPDEST 743 Query: 463 EELSEVPKVEAENISPKSQDIPFVST 488 ELS P +A SPK +P T Sbjct: 744 PELSAEPTPKALENSPKEPGVPTTKT 769 Score = 30.8 bits (68), Expect = 7.9 Identities = 47/230 (20%), Positives = 76/230 (33%), Gaps = 28/230 (12%) Query: 222 SCQISQNLDIMKEKENKGFFSFFQRSKKKRDQTASAPATPLVNKHRPTFTR--SNTISKP 279 S + +Q+++ K+ + K + T PA + PT + ++T K Sbjct: 172 SAKETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKE 231 Query: 280 YISNTLPSDAPKKRRAPLPPMPASQ-SVPQDLAHIQERPASCIVKSMSVDETDKSPCEAG 338 T+ S AP + P P S + P++ A + + T K P Sbjct: 232 PTPTTIKS-APTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAP-- 288 Query: 339 RVRAGSLQLSSMSAGNSSLRRTKRKAPSPPSKIPPHQSDENSRVTALQPVDGVPPDSASE 398 + S+ K AP+ P K P E + T +P P + A Sbjct: 289 ------------TTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPT 336 Query: 399 ANSPEELSSPETFHPGLSSQEQCTAPKLMEETSVFE-CPGTPEAAITSLT 447 P P + TAPK T+ E P TP+ + T Sbjct: 337 TKEPA---------PTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTT 377 >gi|189181722 proteoglycan 4 isoform C [Homo sapiens] Length = 1311 Score = 42.7 bits (99), Expect = 0.002 Identities = 66/327 (20%), Positives = 107/327 (32%), Gaps = 35/327 (10%) Query: 708 PLTVKDPICAHGNDDLLPPVDRIDKNSTASYLKNYPLYRQDYNPKP--KPSNEITREYIP 765 P T K+P + P K + K+ P ++ P KP+ +E P Sbjct: 305 PTTTKEPAPTTPKE----PAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAP 360 Query: 766 KIGMTTYKIVPPKSLEISKDWQSETIEYKDDQDMHALGKKHTHENVKETAIQTEDSAISE 825 TT K P + + E + KK KE A T Sbjct: 361 ----TTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPT 416 Query: 826 SPEEPLPNLKPKPNLRTEHQVPSSVSSP-----DDAMVSPLKPAPKMTRDTG-TAPFAPN 879 + +EP P +P T P++ P A +P +P+P T++ T P P Sbjct: 417 TTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPA 476 Query: 880 LEEINNILESKFKSRASNAQAKPSSFFLQMQKRVSGHYVTSAAAKSVHAAPNPAPKELTN 939 + K A +P+ T A + P P + T Sbjct: 477 PTTPKKPAPTTPKEPAPTTPKEPAP------------TTTKKPAPTTPKEPAPTTPKETA 524 Query: 940 KEAERDMLPSPEQTLSPLSKMPHSVPQPLVEKTDDDVIGQAPAEASP-PPIAPKPVTIPA 998 + + P+ + L+P + P+ T +++ P E +P P P P T A Sbjct: 525 PTTPKKLTPTTPEKLAP------TTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKA 578 Query: 999 SQVSTQNLKTLKTFGAPRPYSSSGPSP 1025 + +T T P P + P+P Sbjct: 579 AAPNTPKEPAPTTPKEPAPTTPKEPAP 605 Score = 41.2 bits (95), Expect = 0.006 Identities = 80/390 (20%), Positives = 126/390 (32%), Gaps = 66/390 (16%) Query: 750 NPKPK--PSNEITREYIPKIGMTTY---KIVPPKSLEISKDWQSETIEYKDDQDMHALGK 804 NP+P P+++ ++E + T K + + S D + +T K+ Q + Sbjct: 166 NPRPSLPPNSDTSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSA 225 Query: 805 KH--------------THENVKETAIQTEDSAISESPEEPLPNLKPKPNLRTEHQVPSSV 850 K K A+ T +P+EP +P P+++ Sbjct: 226 KDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEP-------TPTTI 278 Query: 851 SSPDDAMVSPLKPAPKMTRDTGTAPFAPNLEEINNILESKFKSRASNAQAKPSSFFLQMQ 910 S A +P +PAP T+ T P P + K A +P+ Sbjct: 279 KS---APTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAP------ 329 Query: 911 KRVSGHYVTSAAAKSVHAAPNPA----PKELTNKEAERDMLPSPEQTLSPLSKMPHSVPQ 966 T+ +A + P P P T KE P+P P P P Sbjct: 330 -------TTTKSAPTTPKEPAPTTPKKPAPTTPKE------PAPTTPKEPTPTTPKE-PA 375 Query: 967 PLVEKTDDDVIGQAPAEASP-PPIAPKPVTIPASQVSTQNLKTLKTFGAPRPYSSSGPSP 1025 P T + P E +P P P P T +T T P P + P+P Sbjct: 376 P----TTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAP 431 Query: 1026 FALAVVKRSQSFSKERTESPSASALVQP----PANTEE-GKTHSVNKFVDIPQLGVSDKE 1080 K + + +KE + + SA P P T+E T P+ Sbjct: 432 ---TTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTP 488 Query: 1081 NNSAHNEQNSQIPTPTDGPSFTVMRQSSLT 1110 A PT T P+ T ++ + T Sbjct: 489 KEPAPTTPKEPAPTTTKKPAPTTPKEPAPT 518 Score = 39.7 bits (91), Expect = 0.017 Identities = 60/274 (21%), Positives = 97/274 (35%), Gaps = 43/274 (15%) Query: 251 RDQTASAPATPLVNKHRPTFTRSNTISKPYISNTLPSDAPK--KRRAPLPPMPASQSVPQ 308 ++ + P P + PT T+ T S T AP K AP P + + P+ Sbjct: 625 KEPAPTTPKKPAPKELAPTTTKEPT------STTCDKPAPTTPKGTAPTTPKEPAPTTPK 678 Query: 309 DLAHIQERPASCIVKSMSVDETDKSPCE---AGRVRAGSLQLSSMSAGNSSLRRT----- 360 + A + + T K P A G +S ++ + T Sbjct: 679 EPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTP 738 Query: 361 --------KRKAPSPPSKIPPHQSDENSRVTALQPV------DGVPPDSASEA------N 400 K+ AP+ P PP S+ ++ T +P D P+ ++E N Sbjct: 739 KEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALEN 798 Query: 401 SPEELSSPETFHPGLSSQEQCTAPKLMEETSVFECPGTPEAAITSLTSGISSDYSLEEID 460 SP+E P T P + E T K ++T+ + TPE + T+ Sbjct: 799 SPKEPGVPTTKTPAATKPEMTTTAK--DKTTERDLRTTPE----TTTAAPKMTKETATTT 852 Query: 461 EKEELSEVPKVEAENISPKSQD-IPFVSTDIINT 493 EK S++ + S +QD PF T + T Sbjct: 853 EKTTESKITATTTQVTSTTTQDTTPFKITTLKTT 886 Score = 37.0 bits (84), Expect = 0.11 Identities = 53/262 (20%), Positives = 87/262 (33%), Gaps = 27/262 (10%) Query: 807 THENVKETAIQTEDSAISESPEEPLPNLKPKPNLRTEHQVPSSVSSPDDAMVSPLKPAPK 866 T V E + I +SP+E P L +P + P P + KP Sbjct: 760 TTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEPGVPTTKTPAATKPEMT 819 Query: 867 MT-RDTGTAPFAPNLEEINNILESKFKSRASNAQAKPSSFFLQMQKRVSGHYVTSAAAKS 925 T +D T E K A+ + S +V+ Sbjct: 820 TTAKDKTTERDLRTTPETTTAAPKMTKETATTTEKTTESKITATTTQVTSTTTQDTTPFK 879 Query: 926 VHAAPNP--APKELTNKE--AERDMLPSPEQTLSPLSKMPHS---VPQPLVEKTDDDVIG 978 + APK T K+ +++ PE+T P + +S P+P Sbjct: 880 ITTLKTTTLAPKVTTTKKTITTTEIMNKPEETAKPKDRATNSKATTPKP----------- 928 Query: 979 QAPAEASPPPIA-PKPVTIPASQVSTQNLKTLKTFGAPRPYSSSGPSPFALAVVKRSQSF 1037 Q P +A P + KP T+P ++ KT PR +S+ P + + + Sbjct: 929 QKPTKAPKKPTSTKKPKTMP-------RVRKPKTTPTPRKMTSTMPELNPTSRIAEAMLQ 981 Query: 1038 SKERTESPSASALVQPPANTEE 1059 + R S LV+ +E+ Sbjct: 982 TTTRPNQTPNSKLVEVNPKSED 1003 Score = 36.2 bits (82), Expect = 0.19 Identities = 39/196 (19%), Positives = 68/196 (34%), Gaps = 6/196 (3%) Query: 247 SKKKRDQTASAPATPLVNKHRPTFTRSNTISKPYISNTLPSDAPKKRRAPLPPMPASQSV 306 +K+ T PA K PT + + P P+ K +P P + + Sbjct: 378 TKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTP----KEPAPTTTKEPSPTTPKEPAPTT 433 Query: 307 PQDLAHIQERPASCIVKSMSVDETDKSPCEAGRVRAGSLQLSSMSAGNSSLRRT-KRKAP 365 + + PA KS + SP + + + + T K AP Sbjct: 434 TKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAP 493 Query: 366 SPPSKIPPHQSDENSRVTALQPVDGVPPDSASEANSPEELSSPETFHPGLSSQEQCTAPK 425 + P + P + + + T +P P ++A ++PE P + T P+ Sbjct: 494 TTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPE 553 Query: 426 LMEETSVFE-CPGTPE 440 + T+ E P TPE Sbjct: 554 ELAPTTPEEPTPTTPE 569 Score = 36.2 bits (82), Expect = 0.19 Identities = 69/315 (21%), Positives = 99/315 (31%), Gaps = 31/315 (9%) Query: 812 KETAIQTEDSAISESPEEPLPNLKPKPNLRTEHQVPSSVSSPDDAMVSPLKPAPKMTRDT 871 KE A T +P+EP P PK T + + + A +P KPAP + Sbjct: 497 KEPAPTTTKKPAPTTPKEPAPTT-PKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEEL 555 Query: 872 G-TAPFAPNLEEINNILESKFKSRASNAQAKPSSFFLQMQKRVSGHYVTSAAAKSVHAAP 930 T P P + K+ A N +P+ + + K A Sbjct: 556 APTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKET-APT 614 Query: 931 NP---APKELTNKEAERDMLPSPEQTLSPLSKMPHSV----PQPLVEKTDDDVIGQAPAE 983 P AP L P+P++ +K P S P P K + PA Sbjct: 615 TPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAP 674 Query: 984 ASPPPIAPKPVTIPASQVSTQNLKTLKTFGAPRPYSSSGPSPFALAVV----KRSQSFSK 1039 +P AP T P T T P P + P+P LA S + K Sbjct: 675 TTPKEPAP---TTPKGTAPT-------TLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDK 724 Query: 1040 ERTESPSASALVQP--PANTEEGKTHSVNKFVDIPQLG-----VSDKENNSAHNEQNSQI 1092 +P +A P PA T K P + KE + H + Sbjct: 725 PAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDEST 784 Query: 1093 PTPTDGPSFTVMRQS 1107 P + P+ + S Sbjct: 785 PELSAEPTPKALENS 799 Score = 35.8 bits (81), Expect = 0.24 Identities = 48/202 (23%), Positives = 73/202 (36%), Gaps = 10/202 (4%) Query: 247 SKKKRDQTASAPATPLVNKHRPTFTR----SNTISKPYISNTLPSDAPKKRRAPLPPMPA 302 +K+ T PA P K PT T+ + T S P PS K AP P Sbjct: 418 TKEPSPTTPKEPA-PTTTKSAPTTTKEPAPTTTKSAPTTPKE-PSPTTTKEPAPTTPKEP 475 Query: 303 SQSVPQDLAHIQER-PASCIVKSMSVDETDKSPCEAGRVRAGSLQLSSMSAGNSSLRRT- 360 + + P+ A + PA K + T K + A + + L T Sbjct: 476 APTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTT 535 Query: 361 -KRKAPSPPSKIPPHQSDENSRVTALQPVDGVPPDSASEANSPEELSSPETFHPGLSSQE 419 ++ AP+ P K P +E + T +P P + A ++P+ P + Sbjct: 536 PEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEP 595 Query: 420 QCTAPKLMEETSVFE-CPGTPE 440 T PK T+ E P TP+ Sbjct: 596 APTTPKEPAPTTPKETAPTTPK 617 Score = 35.8 bits (81), Expect = 0.24 Identities = 58/266 (21%), Positives = 94/266 (35%), Gaps = 37/266 (13%) Query: 257 APATPLVNKHRPTFTRSNTISKPY--ISNTLPSDAPK--KRRAPLPPMPASQSVPQDLAH 312 AP TP + PT T + P T + AP K AP P + + P++ A Sbjct: 548 APTTP--EELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAP 605 Query: 313 IQERPASCIVKSMSVDETDKSPCEAGRVRAGSLQLSSMSAGNSSLRRTKRKAPSPPSKIP 372 + + + T K P + +L+ + + + AP+ P Sbjct: 606 TTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTA 665 Query: 373 PHQSDENSRVTALQPVDGVPPDSA-----------SEANSPEELSSPETFHPGLSSQEQ- 420 P E + T +P P +A + +P+EL+ T P ++ ++ Sbjct: 666 PTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKP 725 Query: 421 -CTAPKLMEETSVFE---------CPGTPEAAITSLTSGISSDYSLEE--------IDEK 462 T PK T+ E P TPE TS +S+ + +E + Sbjct: 726 APTTPKETAPTTPKEPAPTTPKKPAPTTPETP-PPTTSEVSTPTTTKEPTTIHKSPDEST 784 Query: 463 EELSEVPKVEAENISPKSQDIPFVST 488 ELS P +A SPK +P T Sbjct: 785 PELSAEPTPKALENSPKEPGVPTTKT 810 Score = 30.8 bits (68), Expect = 7.9 Identities = 47/230 (20%), Positives = 76/230 (33%), Gaps = 28/230 (12%) Query: 222 SCQISQNLDIMKEKENKGFFSFFQRSKKKRDQTASAPATPLVNKHRPTFTR--SNTISKP 279 S + +Q+++ K+ + K + T PA + PT + ++T K Sbjct: 213 SAKETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKE 272 Query: 280 YISNTLPSDAPKKRRAPLPPMPASQ-SVPQDLAHIQERPASCIVKSMSVDETDKSPCEAG 338 T+ S AP + P P S + P++ A + + T K P Sbjct: 273 PTPTTIKS-APTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAP-- 329 Query: 339 RVRAGSLQLSSMSAGNSSLRRTKRKAPSPPSKIPPHQSDENSRVTALQPVDGVPPDSASE 398 + S+ K AP+ P K P E + T +P P + A Sbjct: 330 ------------TTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPT 377 Query: 399 ANSPEELSSPETFHPGLSSQEQCTAPKLMEETSVFE-CPGTPEAAITSLT 447 P P + TAPK T+ E P TP+ + T Sbjct: 378 TKEPA---------PTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTT 418 >gi|157738649 neurofilament, medium polypeptide 150kDa isoform 1 [Homo sapiens] Length = 916 Score = 42.7 bits (99), Expect = 0.002 Identities = 49/231 (21%), Positives = 87/231 (37%), Gaps = 25/231 (10%) Query: 404 ELSSPETFHPGLSSQEQCTAPKLMEETSVFECPGTPEAAITSLTSGISSDYSLEEIDEKE 463 ++ P+ P L Q + +++EET V + E A+T++T ++ E+ + E Sbjct: 435 KIQKPKVEAPKLKVQHKFVE-EIIEETKVEDEKSEMEEALTAITEELAVSMKEEKKEAAE 493 Query: 464 ELSEVPKVEAENISPKSQDIPFVSTDIINTLKNDPDSALGNGSGEFSQNSMEEKQETKST 523 E E P+ E E ++ K + + ++ G E Q EE+ E + Sbjct: 494 EKEEEPEAEEEEVAAKKSPVKATAPEV--------KEEEGEKEEEEGQEEEEEEDEGAKS 545 Query: 524 DGQEPHSVVYDTSNGKKVVDSIRNLKSLGPNQENVQNEIIVYPENTEDNMKNGVKKTEIN 583 D E + S+ K+ E + E E E K KK E Sbjct: 546 DQAEEGGSEKEGSSEKE-------------EGEQEEGETEAEAEGEEAEAKE-EKKVEEK 591 Query: 584 VEGVAKNNNI--DMEVERPSNSEAHETDTAISYKENHLAASSVPDQKLNQP 632 E VA + D +VE+P +++ + + K S ++K P Sbjct: 592 SEEVATKEELVADAKVEKPEKAKSPVPKSPVEEKGKSPVPKSPVEEKGKSP 642 >gi|157738641 neurofilament, medium polypeptide 150kDa isoform 2 [Homo sapiens] Length = 540 Score = 42.7 bits (99), Expect = 0.002 Identities = 49/231 (21%), Positives = 87/231 (37%), Gaps = 25/231 (10%) Query: 404 ELSSPETFHPGLSSQEQCTAPKLMEETSVFECPGTPEAAITSLTSGISSDYSLEEIDEKE 463 ++ P+ P L Q + +++EET V + E A+T++T ++ E+ + E Sbjct: 59 KIQKPKVEAPKLKVQHKFVE-EIIEETKVEDEKSEMEEALTAITEELAVSMKEEKKEAAE 117 Query: 464 ELSEVPKVEAENISPKSQDIPFVSTDIINTLKNDPDSALGNGSGEFSQNSMEEKQETKST 523 E E P+ E E ++ K + + ++ G E Q EE+ E + Sbjct: 118 EKEEEPEAEEEEVAAKKSPVKATAPEV--------KEEEGEKEEEEGQEEEEEEDEGAKS 169 Query: 524 DGQEPHSVVYDTSNGKKVVDSIRNLKSLGPNQENVQNEIIVYPENTEDNMKNGVKKTEIN 583 D E + S+ K+ E + E E E K KK E Sbjct: 170 DQAEEGGSEKEGSSEKE-------------EGEQEEGETEAEAEGEEAEAKE-EKKVEEK 215 Query: 584 VEGVAKNNNI--DMEVERPSNSEAHETDTAISYKENHLAASSVPDQKLNQP 632 E VA + D +VE+P +++ + + K S ++K P Sbjct: 216 SEEVATKEELVADAKVEKPEKAKSPVPKSPVEEKGKSPVPKSPVEEKGKSP 266 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.307 0.124 0.346 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 49,643,883 Number of Sequences: 37866 Number of extensions: 2633682 Number of successful extensions: 13051 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 26 Number of HSP's successfully gapped in prelim test: 534 Number of HSP's that attempted gapping in prelim test: 11171 Number of HSP's gapped (non-prelim): 2137 length of query: 1166 length of database: 18,247,518 effective HSP length: 113 effective length of query: 1053 effective length of database: 13,968,660 effective search space: 14708998980 effective search space used: 14708998980 T: 11 A: 40 X1: 16 ( 7.1 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 42 (21.6 bits) S2: 68 (30.8 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.