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Search of human proteins with 62414289
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|62414289 vimentin [Homo sapiens]
(466 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|62414289 vimentin [Homo sapiens] 892 0.0
gi|55749932 desmin [Homo sapiens] 551 e-157
gi|21264345 peripherin [Homo sapiens] 501 e-142
gi|4503979 glial fibrillary acidic protein isoform 1 [Homo sapiens] 492 e-139
gi|196115290 glial fibrillary acidic protein isoform 2 [Homo sap... 454 e-127
gi|14249342 internexin neuronal intermediate filament protein, a... 375 e-104
gi|105990539 neurofilament, light polypeptide 68kDa [Homo sapiens] 355 5e-98
gi|157738649 neurofilament, medium polypeptide 150kDa isoform 1 ... 346 3e-95
gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens] 295 5e-80
gi|4504919 keratin 8 [Homo sapiens] 265 7e-71
gi|67782365 keratin 7 [Homo sapiens] 244 9e-65
gi|153791158 keratin 75 [Homo sapiens] 242 6e-64
gi|119395754 keratin 5 [Homo sapiens] 240 2e-63
gi|119395750 keratin 1 [Homo sapiens] 239 4e-63
gi|155969697 keratin 6C [Homo sapiens] 238 7e-63
gi|119703753 keratin 6B [Homo sapiens] 237 2e-62
gi|15431316 keratin, hair, basic, 4 [Homo sapiens] 234 1e-61
gi|5031839 keratin 6A [Homo sapiens] 234 2e-61
gi|109148552 keratin 3 [Homo sapiens] 231 1e-60
gi|32567786 keratin 6L [Homo sapiens] 230 2e-60
gi|28173564 keratin 73 [Homo sapiens] 229 3e-60
gi|109255249 keratin 4 [Homo sapiens] 225 8e-59
gi|153791670 keratin 76 [Homo sapiens] 224 1e-58
gi|15618995 keratin 71 [Homo sapiens] 224 2e-58
gi|239755818 PREDICTED: hypothetical protein isoform 2 [Homo sap... 221 8e-58
gi|239755816 PREDICTED: hypothetical protein isoform 1 [Homo sap... 221 8e-58
gi|239755814 PREDICTED: hypothetical protein isoform 3 [Homo sap... 221 8e-58
gi|14318422 keratin 86 [Homo sapiens] 221 8e-58
gi|169790841 keratin 83 [Homo sapiens] 220 2e-57
gi|148612803 keratin 6 irs4 [Homo sapiens] 220 2e-57
>gi|62414289 vimentin [Homo sapiens]
Length = 466
Score = 892 bits (2306), Expect = 0.0
Identities = 466/466 (100%), Positives = 466/466 (100%)
Query: 1 MSTRSVSSSSYRRMFGGPGTASRPSSSRSYVTTSTRTYSLGSALRPSTSRSLYASSPGGV 60
MSTRSVSSSSYRRMFGGPGTASRPSSSRSYVTTSTRTYSLGSALRPSTSRSLYASSPGGV
Sbjct: 1 MSTRSVSSSSYRRMFGGPGTASRPSSSRSYVTTSTRTYSLGSALRPSTSRSLYASSPGGV 60
Query: 61 YATRSSAVRLRSSVPGVRLLQDSVDFSLADAINTEFKNTRTNEKVELQELNDRFANYIDK 120
YATRSSAVRLRSSVPGVRLLQDSVDFSLADAINTEFKNTRTNEKVELQELNDRFANYIDK
Sbjct: 61 YATRSSAVRLRSSVPGVRLLQDSVDFSLADAINTEFKNTRTNEKVELQELNDRFANYIDK 120
Query: 121 VRFLEQQNKILLAELEQLKGQGKSRLGDLYEEEMRELRRQVDQLTNDKARVEVERDNLAE 180
VRFLEQQNKILLAELEQLKGQGKSRLGDLYEEEMRELRRQVDQLTNDKARVEVERDNLAE
Sbjct: 121 VRFLEQQNKILLAELEQLKGQGKSRLGDLYEEEMRELRRQVDQLTNDKARVEVERDNLAE 180
Query: 181 DIMRLREKLQEEMLQREEAENTLQSFRQDVDNASLARLDLERKVESLQEEIAFLKKLHEE 240
DIMRLREKLQEEMLQREEAENTLQSFRQDVDNASLARLDLERKVESLQEEIAFLKKLHEE
Sbjct: 181 DIMRLREKLQEEMLQREEAENTLQSFRQDVDNASLARLDLERKVESLQEEIAFLKKLHEE 240
Query: 241 EIQELQAQIQEQHVQIDVDVSKPDLTAALRDVRQQYESVAAKNLQEAEEWYKSKFADLSE 300
EIQELQAQIQEQHVQIDVDVSKPDLTAALRDVRQQYESVAAKNLQEAEEWYKSKFADLSE
Sbjct: 241 EIQELQAQIQEQHVQIDVDVSKPDLTAALRDVRQQYESVAAKNLQEAEEWYKSKFADLSE 300
Query: 301 AANRNNDALRQAKQESTEYRRQVQSLTCEVDALKGTNESLERQMREMEENFAVEAANYQD 360
AANRNNDALRQAKQESTEYRRQVQSLTCEVDALKGTNESLERQMREMEENFAVEAANYQD
Sbjct: 301 AANRNNDALRQAKQESTEYRRQVQSLTCEVDALKGTNESLERQMREMEENFAVEAANYQD 360
Query: 361 TIGRLQDEIQNMKEEMARHLREYQDLLNVKMALDIEIATYRKLLEGEESRISLPLPNFSS 420
TIGRLQDEIQNMKEEMARHLREYQDLLNVKMALDIEIATYRKLLEGEESRISLPLPNFSS
Sbjct: 361 TIGRLQDEIQNMKEEMARHLREYQDLLNVKMALDIEIATYRKLLEGEESRISLPLPNFSS 420
Query: 421 LNLRETNLDSLPLVDTHSKRTLLIKTVETRDGQVINETSQHHDDLE 466
LNLRETNLDSLPLVDTHSKRTLLIKTVETRDGQVINETSQHHDDLE
Sbjct: 421 LNLRETNLDSLPLVDTHSKRTLLIKTVETRDGQVINETSQHHDDLE 466
>gi|55749932 desmin [Homo sapiens]
Length = 470
Score = 551 bits (1420), Expect = e-157
Identities = 291/464 (62%), Positives = 365/464 (78%), Gaps = 12/464 (2%)
Query: 9 SSYRRMFGG-PG-----TASRPSSSRSYVTTSTRTYSLGSALRPSTSRSLYASSPGGVYA 62
SSYRR FGG PG S P R+ + + S+ S + + S A G + A
Sbjct: 12 SSYRRTFGGAPGFPLGSPLSSPVFPRAGFGSKGSSSSVTSRVYQVSRTSGGAGGLGSLRA 71
Query: 63 TRSSAVRLRSSVPGVRLLQDSVDFSLADAINTEFKNTRTNEKVELQELNDRFANYIDKVR 122
+R R SS LL DFSLADA+N EF TRTNEKVELQELNDRFANYI+KVR
Sbjct: 72 SRLGTTRTPSSYGAGELL----DFSLADAVNQEFLTTRTNEKVELQELNDRFANYIEKVR 127
Query: 123 FLEQQNKILLAELEQLKGQGKSRLGDLYEEEMRELRRQVDQLTNDKARVEVERDNLAEDI 182
FLEQQN L AE+ +LKG+ +R+ +LYEEE+RELRRQV+ LTN +ARV+VERDNL +D+
Sbjct: 128 FLEQQNAALAAEVNRLKGREPTRVAELYEEELRELRRQVEVLTNQRARVDVERDNLLDDL 187
Query: 183 MRLREKLQEEMLQREEAENTLQSFRQDVDNASLARLDLERKVESLQEEIAFLKKLHEEEI 242
RL+ KLQEE+ +EEAEN L +FR DVD A+LAR+DLER++ESL EEIAFLKK+HEEEI
Sbjct: 188 QRLKAKLQEEIQLKEEAENNLAAFRADVDAATLARIDLERRIESLNEEIAFLKKVHEEEI 247
Query: 243 QELQAQIQEQHVQIDVDVSKPDLTAALRDVRQQYESVAAKNLQEAEEWYKSKFADLSEAA 302
+ELQAQ+QEQ VQ+++D+SKPDLTAALRD+R QYE++AAKN+ EAEEWYKSK +DL++AA
Sbjct: 248 RELQAQLQEQQVQVEMDMSKPDLTAALRDIRAQYETIAAKNISEAEEWYKSKVSDLTQAA 307
Query: 303 NRNNDALRQAKQESTEYRRQVQSLTCEVDALKGTNESLERQMREMEENFAVEAANYQDTI 362
N+NNDALRQAKQE EYR Q+QS TCE+DALKGTN+SL RQMRE+E+ FA EA+ YQD I
Sbjct: 308 NKNNDALRQAKQEMMEYRHQIQSYTCEIDALKGTNDSLMRQMRELEDRFASEASGYQDNI 367
Query: 363 GRLQDEIQNMKEEMARHLREYQDLLNVKMALDIEIATYRKLLEGEESRISLPLPNFSSLN 422
RL++EI+++K+EMARHLREYQDLLNVKMALD+EIATYRKLLEGEESRI+LP+ +S+LN
Sbjct: 368 ARLEEEIRHLKDEMARHLREYQDLLNVKMALDVEIATYRKLLEGEESRINLPIQTYSALN 427
Query: 423 LRETNLDSLPLVDTHSKRTLLIKTVETRDGQVINE-TSQHHDDL 465
RET+ + + H+K+T++IKT+ETRDG+V++E T Q H+ L
Sbjct: 428 FRETSPEQRG-SEVHTKKTVMIKTIETRDGEVVSEATQQQHEVL 470
>gi|21264345 peripherin [Homo sapiens]
Length = 470
Score = 501 bits (1290), Expect = e-142
Identities = 271/463 (58%), Positives = 358/463 (77%), Gaps = 28/463 (6%)
Query: 7 SSSSYRRMFGGPGTASRPSSSRSYVTTSTRTYSLGSALRPSTSRSLYASSPGGVYATRSS 66
SS+SYRR FG P PS S +S S+ R S+SR L ++SP SS
Sbjct: 13 SSTSYRRTFGPP-----PSLSPG-------AFSYSSSSRFSSSRLLGSASP-------SS 53
Query: 67 AVRL---RSSVPG----VRLLQDSVDFSLADAINTEFKNTRTNEKVELQELNDRFANYID 119
+VRL RS G +RL + +DFS+A+A+N EF TR+NEK ELQELNDRFAN+I+
Sbjct: 54 SVRLGSFRSPRAGAGALLRLPSERLDFSMAEALNQEFLATRSNEKQELQELNDRFANFIE 113
Query: 120 KVRFLEQQNKILLAELEQLKGQGKSRLGDLYEEEMRELRRQVDQLTNDKARVEVERDNLA 179
KVRFLEQQN L EL Q +GQ +R L ++E+RELRR+++ L ++ RV+VERD LA
Sbjct: 114 KVRFLEQQNAALRGELSQARGQEPARADQLCQQELRELRRELELLGRERDRVQVERDGLA 173
Query: 180 EDIMRLREKLQEEMLQREEAENTLQSFRQDVDNASLARLDLERKVESLQEEIAFLKKLHE 239
ED+ L+++L+EE +RE+AE+ L FR+DVD+A+L+RL+LERK+ESL +EI FLKKLHE
Sbjct: 174 EDLAALKQRLEEETRKREDAEHNLVLFRKDVDDATLSRLELERKIESLMDEIEFLKKLHE 233
Query: 240 EEIQELQAQIQEQHVQ-IDVDVS-KPDLTAALRDVRQQYESVAAKNLQEAEEWYKSKFAD 297
EE+++LQ ++ Q VQ ++V+ + KP+LTAALRD+R QYES+AAKNLQEAEEWYKSK+AD
Sbjct: 234 EELRDLQVSVESQQVQQVEVEATVKPELTAALRDIRAQYESIAAKNLQEAEEWYKSKYAD 293
Query: 298 LSEAANRNNDALRQAKQESTEYRRQVQSLTCEVDALKGTNESLERQMREMEENFAVEAAN 357
LS+AANRN++ALRQAKQE E RRQ+QSLTCEVD L+GTNE+L RQ+RE+EE FA+EA
Sbjct: 294 LSDAANRNHEALRQAKQEMNESRRQIQSLTCEVDGLRGTNEALLRQLRELEEQFALEAGG 353
Query: 358 YQDTIGRLQDEIQNMKEEMARHLREYQDLLNVKMALDIEIATYRKLLEGEESRISLPLPN 417
YQ RL++E++ +KEEMARHLREYQ+LLNVKMALDIEIATYRKLLEGEESRIS+P+ +
Sbjct: 354 YQAGAARLEEELRQLKEEMARHLREYQELLNVKMALDIEIATYRKLLEGEESRISVPVHS 413
Query: 418 FSSLNLRETNLDSLPLVDTHSKRTLLIKTVETRDGQVINETSQ 460
F+SLN++ T + P D+HS++T+LIKT+ETR+G+V+ E+ +
Sbjct: 414 FASLNIKTTVPEVEPPQDSHSRKTVLIKTIETRNGEVVTESQK 456
>gi|4503979 glial fibrillary acidic protein isoform 1 [Homo sapiens]
Length = 432
Score = 492 bits (1266), Expect = e-139
Identities = 248/427 (58%), Positives = 333/427 (77%), Gaps = 11/427 (2%)
Query: 47 STSRSLYASSPGGVYATRSSAVRLRSSVPGVRL--------LQDSVDFSLADAINTEFKN 98
S +R Y SS + + RL PG RL L VDFSLA A+N FK
Sbjct: 8 SAARRSYVSSGEMMVGGLAPGRRLG---PGTRLSLARMPPPLPTRVDFSLAGALNAGFKE 64
Query: 99 TRTNEKVELQELNDRFANYIDKVRFLEQQNKILLAELEQLKGQGKSRLGDLYEEEMRELR 158
TR +E+ E+ ELNDRFA+YI+KVRFLEQQNK L AEL QL+ + ++L D+Y+ E+RELR
Sbjct: 65 TRASERAEMMELNDRFASYIEKVRFLEQQNKALAAELNQLRAKEPTKLADVYQAELRELR 124
Query: 159 RQVDQLTNDKARVEVERDNLAEDIMRLREKLQEEMLQREEAENTLQSFRQDVDNASLARL 218
++DQLT + AR+EVERDNLA+D+ +R+KLQ+E R EAEN L ++RQ+ D A+LARL
Sbjct: 125 LRLDQLTANSARLEVERDNLAQDLATVRQKLQDETNLRLEAENNLAAYRQEADEATLARL 184
Query: 219 DLERKVESLQEEIAFLKKLHEEEIQELQAQIQEQHVQIDVDVSKPDLTAALRDVRQQYES 278
DLERK+ESL+EEI FL+K+HEEE++ELQ Q+ Q V +++DV+KPDLTAAL+++R QYE+
Sbjct: 185 DLERKIESLEEEIRFLRKIHEEEVRELQEQLARQQVHVELDVAKPDLTAALKEIRTQYEA 244
Query: 279 VAAKNLQEAEEWYKSKFADLSEAANRNNDALRQAKQESTEYRRQVQSLTCEVDALKGTNE 338
+A+ N+ EAEEWY+SKFADL++AA RN + LRQAK E+ +YRRQ+QSLTC++++L+GTNE
Sbjct: 245 MASSNMHEAEEWYRSKFADLTDAAARNAELLRQAKHEANDYRRQLQSLTCDLESLRGTNE 304
Query: 339 SLERQMREMEENFAVEAANYQDTIGRLQDEIQNMKEEMARHLREYQDLLNVKMALDIEIA 398
SLERQMRE EE EAA+YQ+ + RL++E Q++K+EMARHL+EYQDLLNVK+ALDIEIA
Sbjct: 305 SLERQMREQEERHVREAASYQEALARLEEEGQSLKDEMARHLQEYQDLLNVKLALDIEIA 364
Query: 399 TYRKLLEGEESRISLPLPNFSSLNLRETNLDSLPLVDTHSKRTLLIKTVETRDGQVINET 458
TYRKLLEGEE+RI++P+ FS+L +RET+LD+ + + H KR +++KTVE RDG+VI E+
Sbjct: 365 TYRKLLEGEENRITIPVQTFSNLQIRETSLDTKSVSEGHLKRNIVVKTVEMRDGEVIKES 424
Query: 459 SQHHDDL 465
Q H D+
Sbjct: 425 KQEHKDV 431
>gi|196115290 glial fibrillary acidic protein isoform 2 [Homo
sapiens]
Length = 431
Score = 454 bits (1167), Expect = e-127
Identities = 235/422 (55%), Positives = 319/422 (75%), Gaps = 13/422 (3%)
Query: 47 STSRSLYASSPGGVYATRSSAVRLRSSVPGVRL--------LQDSVDFSLADAINTEFKN 98
S +R Y SS + + RL PG RL L VDFSLA A+N FK
Sbjct: 8 SAARRSYVSSGEMMVGGLAPGRRLG---PGTRLSLARMPPPLPTRVDFSLAGALNAGFKE 64
Query: 99 TRTNEKVELQELNDRFANYIDKVRFLEQQNKILLAELEQLKGQGKSRLGDLYEEEMRELR 158
TR +E+ E+ ELNDRFA+YI+KVRFLEQQNK L AEL QL+ + ++L D+Y+ E+RELR
Sbjct: 65 TRASERAEMMELNDRFASYIEKVRFLEQQNKALAAELNQLRAKEPTKLADVYQAELRELR 124
Query: 159 RQVDQLTNDKARVEVERDNLAEDIMRLREKLQEEMLQREEAENTLQSFRQDVDNASLARL 218
++DQLT + AR+EVERDNLA+D+ +R+KLQ+E R EAEN L ++RQ+ D A+LARL
Sbjct: 125 LRLDQLTANSARLEVERDNLAQDLATVRQKLQDETNLRLEAENNLAAYRQEADEATLARL 184
Query: 219 DLERKVESLQEEIAFLKKLHEEEIQELQAQIQEQHVQIDVDVSKPDLTAALRDVRQQYES 278
DLERK+ESL+EEI FL+K+HEEE++ELQ Q+ Q V +++DV+KPDLTAAL+++R QYE+
Sbjct: 185 DLERKIESLEEEIRFLRKIHEEEVRELQEQLARQQVHVELDVAKPDLTAALKEIRTQYEA 244
Query: 279 VAAKNLQEAEEWYKSKFADLSEAANRNNDALRQAKQESTEYRRQVQSLTCEVDALKGTNE 338
+A+ N+ EAEEWY+SKFADL++AA RN + LRQAK E+ +YRRQ+QSLTC++++L+GTNE
Sbjct: 245 MASSNMHEAEEWYRSKFADLTDAAARNAELLRQAKHEANDYRRQLQSLTCDLESLRGTNE 304
Query: 339 SLERQMREMEENFAVEAANYQDTIGRLQDEIQNMKEEMARHLREYQDLLNVKMALDIEIA 398
SLERQMRE EE EAA+YQ+ + RL++E Q++K+EMARHL+EYQDLLNVK+ALDIEIA
Sbjct: 305 SLERQMREQEERHVREAASYQEALARLEEEGQSLKDEMARHLQEYQDLLNVKLALDIEIA 364
Query: 399 TYRKLLEGEESRISLPLPNFSSLNLR--ETNLDSLPLVDTHSKRTLLIKTVETRDGQVIN 456
TYRKLLEGEE+RI++P+ FS+L +R ++ D T ++L I+ + + Q++N
Sbjct: 365 TYRKLLEGEENRITIPVQTFSNLQIRGGKSTKDGENHKVTRYLKSLTIRVIPIQAHQIVN 424
Query: 457 ET 458
T
Sbjct: 425 GT 426
>gi|14249342 internexin neuronal intermediate filament protein,
alpha [Homo sapiens]
Length = 499
Score = 375 bits (964), Expect = e-104
Identities = 214/422 (50%), Positives = 292/422 (69%), Gaps = 20/422 (4%)
Query: 7 SSSSYRRMFGGPGTASRPSSSRSYVTTSTRTYSLGSALRPSTSRSLYASSPGGVYATRSS 66
SSSSYR++FG S S G S SRS ASS A SS
Sbjct: 11 SSSSYRKVFGDGSRLSARLSGAG---------GAGGFRSQSLSRSNVASS-----AACSS 56
Query: 67 AVRLRSSVPGVRL-LQDSVDFSLADAINTEFKNTRTNEKVELQELNDRFANYIDKVRFLE 125
A L + R D +D S A A E+K RTNEK +LQ LNDRFA +I+KV LE
Sbjct: 57 ASSLGLGLAYRRPPASDGLDLSQAAARTNEYKIIRTNEKEQLQGLNDRFAVFIEKVHQLE 116
Query: 126 QQNKILLAELEQLKGQGK--SRLGDLYEEEMRELRRQVDQLTNDKARVEVERDNLAEDIM 183
QN+ L AEL L+ + SR+G+L++ E+R+LR Q+++ ++ +++ +ERD LAE++
Sbjct: 117 TQNRALEAELAALRQRHAEPSRVGELFQRELRDLRAQLEEASSARSQALLERDGLAEEVQ 176
Query: 184 RLREKLQEEMLQREEAENTLQSFRQDVDNASLARLDLERKVESLQEEIAFLKKLHEEEIQ 243
RLR + +EE RE AE L++ ++DVD A+LARLDLE+KVESL +E+AF++++H+EE+
Sbjct: 177 RLRARCEEESRGREGAERALKAQQRDVDGATLARLDLEKKVESLLDELAFVRQVHDEEVA 236
Query: 244 ELQAQIQ---EQHVQIDVDVSKPDLTAALRDVRQQYESVAAKNLQEAEEWYKSKFADLSE 300
EL A +Q + ++DV V+KPDLT+ALR++R QYES+AAKNLQ AEEWYKSKFA+L+E
Sbjct: 237 ELLATLQASSQAAAEVDVTVAKPDLTSALREIRAQYESLAAKNLQSAEEWYKSKFANLNE 296
Query: 301 AANRNNDALRQAKQESTEYRRQVQSLTCEVDALKGTNESLERQMREMEENFAVEAANYQD 360
A R+ +A+R +++E EYRRQ+Q+ T E++ L+G NESLERQ+ E+EE + E A YQD
Sbjct: 297 QAARSTEAIRASREEIHEYRRQLQARTIEIEGLRGANESLERQILELEERHSAEVAGYQD 356
Query: 361 TIGRLQDEIQNMKEEMARHLREYQDLLNVKMALDIEIATYRKLLEGEESRISLPLPNFSS 420
+IG+L+++++N K EMARHLREYQDLLNVKMALDIEIA YRKLLEGEE+R S + S
Sbjct: 357 SIGQLENDLRNTKSEMARHLREYQDLLNVKMALDIEIAAYRKLLEGEETRFSTSGLSISG 416
Query: 421 LN 422
LN
Sbjct: 417 LN 418
>gi|105990539 neurofilament, light polypeptide 68kDa [Homo sapiens]
Length = 543
Score = 355 bits (911), Expect = 5e-98
Identities = 190/390 (48%), Positives = 273/390 (70%), Gaps = 3/390 (0%)
Query: 25 SSSRSYVTTSTRTYSLGSALRPSTSRSLYASSPGGVYATRSSAVRLRSSVPGVRLLQDSV 84
S R YV T R + ST+RS Y+S V ++ S SS + +++
Sbjct: 13 SYKRRYVETP-RVHISSVRSGYSTARSAYSSYSAPVSSSLSVRRSYSSSSGSLMPSLENL 71
Query: 85 DFSLADAINTEFKNTRTNEKVELQELNDRFANYIDKVRFLEQQNKILLAELEQL--KGQG 142
D S AI+ + K+ RT EK +LQ+LNDRFA++I++V LEQQNK+L AEL L K
Sbjct: 72 DLSQVAAISNDLKSIRTQEKAQLQDLNDRFASFIERVHELEQQNKVLEAELLVLRQKHSE 131
Query: 143 KSRLGDLYEEEMRELRRQVDQLTNDKARVEVERDNLAEDIMRLREKLQEEMLQREEAENT 202
SR LYE+E+R+LR + TN+K ++ ER+ L E + L+ + +EE+L RE+AE
Sbjct: 132 PSRFRALYEQEIRDLRLAAEDATNEKQALQGEREGLEETLRNLQARYEEEVLSREDAEGR 191
Query: 203 LQSFRQDVDNASLARLDLERKVESLQEEIAFLKKLHEEEIQELQAQIQEQHVQIDVDVSK 262
L R+ D A+LAR +LE++++SL +EI+FLKK+HEEEI ELQAQIQ + +++DV+K
Sbjct: 192 LMEARKGADEAALARAELEKRIDSLMDEISFLKKVHEEEIAELQAQIQYAQISVEMDVTK 251
Query: 263 PDLTAALRDVRQQYESVAAKNLQEAEEWYKSKFADLSEAANRNNDALRQAKQESTEYRRQ 322
PDL+AAL+D+R QYE +AAKN+Q AEEW+KS+F L+E+A +N DA+R AK E +E RR
Sbjct: 252 PDLSAALKDIRAQYEKLAAKNMQNAEEWFKSRFTVLTESAAKNTDAVRAAKDEVSESRRL 311
Query: 323 VQSLTCEVDALKGTNESLERQMREMEENFAVEAANYQDTIGRLQDEIQNMKEEMARHLRE 382
+++ T E++A +G NE+LE+Q++E+E+ + + QDTI +L++E++ K EMAR+L+E
Sbjct: 312 LKAKTLEIEACRGMNEALEKQLQELEDKQNADISAMQDTINKLENELRTTKSEMARYLKE 371
Query: 383 YQDLLNVKMALDIEIATYRKLLEGEESRIS 412
YQDLLNVKMALDIEIA YRKLLEGEE+R+S
Sbjct: 372 YQDLLNVKMALDIEIAAYRKLLEGEETRLS 401
>gi|157738649 neurofilament, medium polypeptide 150kDa isoform 1
[Homo sapiens]
Length = 916
Score = 346 bits (887), Expect = 3e-95
Identities = 190/414 (45%), Positives = 289/414 (69%), Gaps = 22/414 (5%)
Query: 9 SSYRRMFGGPGTASRPSSSRSYVTTSTRTYSLGSALRPSTSRSLYASSPGGVYATRSSAV 68
S+YRR+ + SR S S S S +++S GS PST S Y S A
Sbjct: 12 SAYRRVTETRSSFSRVSGSPSSGFRS-QSWSRGS---PSTVSSSYKRS--------MLAP 59
Query: 69 RLRSSVPGVRLLQDSVDFSLADAI-------NTEFKNTRTNEKVELQELNDRFANYIDKV 121
RL S + + S+DFS + ++ ++K +R+NEK +LQ LNDRFA YI+KV
Sbjct: 60 RLAYSSAMLSSAESSLDFSQSSSLLNGGSGPGGDYKLSRSNEKEQLQGLNDRFAGYIEKV 119
Query: 122 RFLEQQNKILLAELEQLKGQGKS--RLGDLYEEEMRELRRQVDQLTNDKARVEVERDNLA 179
+LEQQNK + AE++ L+ + S +LGD Y++E+RELR ++ + ++KA+V+++ D+L
Sbjct: 120 HYLEQQNKEIEAEIQALRQKQASHAQLGDAYDQEIRELRATLEMVNHEKAQVQLDSDHLE 179
Query: 180 EDIMRLREKLQEEMLQREEAENTLQSFRQDVDNASLARLDLERKVESLQEEIAFLKKLHE 239
EDI RL+E+ +EE R++ E +++ R+D++ ASL +++L++KV+SLQ+E+AFL+ HE
Sbjct: 180 EDIHRLKERFEEEARLRDDTEAAIRALRKDIEEASLVKVELDKKVQSLQDEVAFLRSNHE 239
Query: 240 EEIQELQAQIQEQHVQID-VDVSKPDLTAALRDVRQQYESVAAKNLQEAEEWYKSKFADL 298
EE+ +L AQIQ H+ ++ D K D++ AL+++R Q ES + +N+ +AEEW+K ++A L
Sbjct: 240 EEVADLLAQIQASHITVERKDYLKTDISTALKEIRSQLESHSDQNMHQAEEWFKCRYAKL 299
Query: 299 SEAANRNNDALRQAKQESTEYRRQVQSLTCEVDALKGTNESLERQMREMEENFAVEAANY 358
+EAA +N +A+R AK+E EYRRQ+QS + E+++++GT ESLERQ+ ++EE + ++Y
Sbjct: 300 TEAAEQNKEAIRSAKEEIAEYRRQLQSKSIELESVRGTKESLERQLSDIEERHNHDLSSY 359
Query: 359 QDTIGRLQDEIQNMKEEMARHLREYQDLLNVKMALDIEIATYRKLLEGEESRIS 412
QDTI +L++E++ K EMARHLREYQDLLNVKMALDIEIA YRKLLEGEE+R S
Sbjct: 360 QDTIQQLENELRGTKWEMARHLREYQDLLNVKMALDIEIAAYRKLLEGEETRFS 413
>gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens]
Length = 1020
Score = 295 bits (756), Expect = 5e-80
Identities = 169/384 (44%), Positives = 251/384 (65%), Gaps = 20/384 (5%)
Query: 99 TRTNEKVELQELNDRFANYIDKVRFLEQQNKILLAELEQLKGQ--GKSRLGDLYEEEMRE 156
T +EK +LQ LNDRFA YIDKVR LE N+ L E L+ Q G+S +G+LYE E+RE
Sbjct: 93 TSRSEKEQLQALNDRFAGYIDKVRQLEAHNRSLEGEAAALRQQQAGRSAMGELYEREVRE 152
Query: 157 LRRQVDQLTNDKARVEVERDNLAEDIMRLREKLQEEMLQREEAENTLQSFRQDVDNASLA 216
+R V +L + ++ +E+++L EDI +R++L +E QREEAE ++ + A A
Sbjct: 153 MRGAVLRLGAARGQLRLEQEHLLEDIAHVRQRLDDEARQREEAEAAARALARFAQEAEAA 212
Query: 217 RLDLERKVESLQEEIAFLKKLHEEEIQELQAQIQ-----EQHVQIDV-DVSKPDLTAALR 270
R+DL++K ++LQEE +L++ H+EE+ EL QIQ + +Q + D K D+T+ALR
Sbjct: 213 RVDLQKKAQALQEECGYLRRHHQEEVGELLGQIQGSGAAQAQMQAETRDALKCDVTSALR 272
Query: 271 DVRQQYESVAAKNLQEAEEWYKSKFADLSEAANRNNDALRQAKQESTEYRRQVQSLTCEV 330
++R Q E A ++ ++EEW++ + LSEAA N DA+R A++E TEYRRQ+Q+ T E+
Sbjct: 273 EIRAQLEGHAVQSTLQSEEWFRVRLDRLSEAAKVNTDAMRSAQEEITEYRRQLQARTTEL 332
Query: 331 DALKGTNESLERQMREMEENFAVEAANYQDTIGRLQDEIQNMKEEMARHLREYQDLLNVK 390
+ALK T +SLERQ E+E+ + A+YQ+ I +L E++N K EMA LREYQDLLNVK
Sbjct: 333 EALKSTKDSLERQRSELEDRHQADIASYQEAIQQLDAELRNTKWEMAAQLREYQDLLNVK 392
Query: 391 MALDIEIATYRKLLEGEESRI-------SLP--LPNFSSL--NLRETNLDSLPLVDTHSK 439
MALDIEIA YRKLLEGEE RI SLP LP S+ +++ + + + +V+ K
Sbjct: 393 MALDIEIAAYRKLLEGEECRIGFGPIPFSLPEGLPKIPSVSTHIKVKSEEKIKVVEKSEK 452
Query: 440 RTLLIKTVETRDGQVINETSQHHD 463
T++++ +T + QV E ++ +
Sbjct: 453 ETVIVEE-QTEETQVTEEVTEEEE 475
>gi|4504919 keratin 8 [Homo sapiens]
Length = 483
Score = 265 bits (677), Expect = 7e-71
Identities = 169/490 (34%), Positives = 269/490 (54%), Gaps = 43/490 (8%)
Query: 1 MSTRSVSSSSYRRMFGGPGTASRPSSSRSYVTTSTRTYSLGSALRPSTSRSLYASSPGGV 60
MS R V+ SY+ GP R SSRSY + S S R +S + GG
Sbjct: 1 MSIR-VTQKSYKVSTSGP----RAFSSRSYTSGPGSRISSSSFSRVGSSN--FRGGLGGG 53
Query: 61 YATRSSAVRLRSSVPGVRLLQDSVDFSLADAINTEFKNTRTNEKVELQELNDRFANYIDK 120
Y S + + LL L ++ + RT EK +++ LN++FA++IDK
Sbjct: 54 YGGASGMGGITAVTVNQSLLSP-----LVLEVDPNIQAVRTQEKEQIKTLNNKFASFIDK 108
Query: 121 VRFLEQQNKILLAELEQLKGQ--GKSRLGDLYEEEMRELRRQVDQLTNDKARVEVERDNL 178
VRFLEQQNK+L + L+ Q +S + +++E + LRRQ++ L +K ++E E N+
Sbjct: 109 VRFLEQQNKMLETKWSLLQQQKTARSNMDNMFESYINNLRRQLETLGQEKLKLEAELGNM 168
Query: 179 AEDIMRLREKLQEEMLQREEAENTLQSFRQDVDNASLARLDLERKVESLQEEIAFLKKLH 238
+ + K ++E+ +R E EN ++DVD A + +++LE ++E L +EI FL++L+
Sbjct: 169 QGLVEDFKNKYEDEINKRTEMENEFVLIKKDVDEAYMNKVELESRLEGLTDEINFLRQLY 228
Query: 239 EEEIQELQAQIQEQHVQIDVDVSKP-DLTAALRDVRQQYESVAAKNLQEAEEWYKSKFAD 297
EEEI+ELQ+QI + V + +D S+ D+ + + +V+ QYE +A ++ EAE Y+ K+ +
Sbjct: 229 EEEIRELQSQISDTSVVLSMDNSRSLDMDSIIAEVKAQYEDIANRSRAEAESMYQIKYEE 288
Query: 298 LSEAANRNNDALRQAKQESTEYRRQVQSLTCEVDALKGTNESLERQMREMEENFAVEAAN 357
L A ++ D LR+ K E +E R + L E++ LKG SLE + + E+ + +
Sbjct: 289 LQSLAGKHGDDLRRTKTEISEMNRNISRLQAEIEGLKGQRASLEAAIADAEQRGELAIKD 348
Query: 358 YQDTIGRLQDEIQNMKEEMARHLREYQDLLNVKMALDIEIATYRKLLEGEESRISLPLPN 417
+ L+ +Q K++MAR LREYQ+L+NVK+ALDIEIATYRKLLEGEESR+ + N
Sbjct: 349 ANAKLSELEAALQRAKQDMARQLREYQELMNVKLALDIEIATYRKLLEGEESRLESGMQN 408
Query: 418 FS-------------------------SLNLRE---TNLDSLPLVDTHSKRTLLIKTVET 449
S S +L + S T S R +++K +ET
Sbjct: 409 MSIHTKTTSGYAGGLSSAYGGLTSPGLSYSLGSSFGSGAGSSSFSRTSSSRAVVVKKIET 468
Query: 450 RDGQVINETS 459
RDG++++E+S
Sbjct: 469 RDGKLVSESS 478
>gi|67782365 keratin 7 [Homo sapiens]
Length = 469
Score = 244 bits (624), Expect = 9e-65
Identities = 151/402 (37%), Positives = 232/402 (57%), Gaps = 18/402 (4%)
Query: 15 FGGPGTASRPSSSRSYVTTSTRTYSLGSALRPSTSRSLYASSPGGVYATRSSAVRLRSSV 74
F G G R SS+R S+ Y LG++ RS Y GG V + S+
Sbjct: 17 FSGRGAQVRLSSARPGGLGSSSLYGLGASRPRVAVRSAY----GGPVGAGIREVTINQSL 72
Query: 75 PGVRLLQDSVDFSLADAINTEFKNTRTNEKVELQELNDRFANYIDKVRFLEQQNKILLAE 134
+ L+ D SL + R E +++ LN++FA++IDKVRFLEQQNK+L +
Sbjct: 73 --LAPLRLDADPSL--------QRVRQEESEQIKTLNNKFASFIDKVRFLEQQNKLLETK 122
Query: 135 ---LEQLKGQGKSRLGDLYEEEMRELRRQVDQLTNDKARVEVERDNLAEDIMRLREKLQE 191
L++ K SRL D++E ++ LR Q++ L D R+E E ++ + + + K ++
Sbjct: 123 WTLLQEQKSAKSSRLPDIFEAQIAGLRGQLEALQVDGGRLEAELRSMQDVVEDFKNKYED 182
Query: 192 EMLQREEAENTLQSFRQDVDNASLARLDLERKVESLQEEIAFLKKLHEEEIQELQAQIQE 251
E+ R AEN ++DVD A +++++LE KV++L +EI FL+ L+E E+ ELQ+QI +
Sbjct: 183 EINHRTAAENEFVVLKKDVDAAYMSKVELEAKVDALNDEINFLRTLNETELTELQSQISD 242
Query: 252 QHVQIDVDVSKP-DLTAALRDVRQQYESVAAKNLQEAEEWYKSKFADLSEAANRNNDALR 310
V + +D S+ DL + +V+ QYE +A + EAE WY++KF L A ++ D LR
Sbjct: 243 TSVVLSMDNSRSLDLDGIIAEVKAQYEEMAKCSRAEAEAWYQTKFETLQAQAGKHGDDLR 302
Query: 311 QAKQESTEYRRQVQSLTCEVDALKGTNESLERQMREMEENFAVEAANYQDTIGRLQDEIQ 370
+ E +E R +Q L E+D +K LE + E EE + + + L+ +Q
Sbjct: 303 NTRNEISEMNRAIQRLQAEIDNIKNQRAKLEAAIAEAEERGELALKDARAKQEELEAALQ 362
Query: 371 NMKEEMARHLREYQDLLNVKMALDIEIATYRKLLEGEESRIS 412
K++MAR LREYQ+L++VK+ALDIEIATYRKLLEGEESR++
Sbjct: 363 RGKQDMARQLREYQELMSVKLALDIEIATYRKLLEGEESRLA 404
>gi|153791158 keratin 75 [Homo sapiens]
Length = 551
Score = 242 bits (617), Expect = 6e-64
Identities = 150/433 (34%), Positives = 244/433 (56%), Gaps = 29/433 (6%)
Query: 7 SSSSYRRMFGGPGTASRPSSSRSYVTTSTRTYSLGSALRPS------------------- 47
SS S R G G R SS+ + S Y+LG A R S
Sbjct: 33 SSVSVARSAAGSGGLGRISSAGASFG-SRSLYNLGGAKRVSINGCGSSCRSGFGGRASNR 91
Query: 48 ---TSRSLYASSPGGVYATRSSAVRLRSSVPGVRLLQDSVDFSLADAINTEFKNTRTNEK 104
S Y GG ++ S V + V + Q S+ L I+ + R E+
Sbjct: 92 FGVNSGFGYGGGVGGGFSGPSFPVCPPGGIQEVTVNQ-SLLTPLHLQIDPTIQRVRAEER 150
Query: 105 VELQELNDRFANYIDKVRFLEQQNKILLAELEQLKGQG----KSRLGDLYEEEMRELRRQ 160
+++ LN++FA++IDKVRFLEQQNK+L + L+ QG + L L++ ELRRQ
Sbjct: 151 EQIKTLNNKFASFIDKVRFLEQQNKVLETKWALLQEQGSRTVRQNLEPLFDSYTSELRRQ 210
Query: 161 VDQLTNDKARVEVERDNLAEDIMRLREKLQEEMLQREEAENTLQSFRQDVDNASLARLDL 220
++ +T ++ R+E E N+ + + + + ++E+ +R AEN + ++DVD A + +++L
Sbjct: 211 LESITTERGRLEAELRNMQDVVEDFKVRYEDEINKRTAAENEFVALKKDVDAAYMNKVEL 270
Query: 221 ERKVESLQEEIAFLKKLHEEEIQELQAQIQEQHVQIDVDVSKP-DLTAALRDVRQQYESV 279
E KV+SL EEI F+ + + E+ +LQ Q+ + V + +D ++ DL + + +V+ QYE +
Sbjct: 271 EAKVKSLPEEINFIHSVFDAELSQLQTQVGDTSVVLSMDNNRNLDLDSIIAEVKAQYEDI 330
Query: 280 AAKNLQEAEEWYKSKFADLSEAANRNNDALRQAKQESTEYRRQVQSLTCEVDALKGTNES 339
A ++ EAE WY++K+ +L A R+ D LR KQE +E R +Q L E+D++K S
Sbjct: 331 ANRSRAEAESWYQTKYEELQVTAGRHGDDLRNTKQEISEMNRMIQRLRAEIDSVKKQCSS 390
Query: 340 LERQMREMEENFAVEAANYQDTIGRLQDEIQNMKEEMARHLREYQDLLNVKMALDIEIAT 399
L+ + + E+ + + + + L++ +Q K++MAR LREYQ+L+N+K+ALD+EIAT
Sbjct: 391 LQTAIADAEQRGELALKDARAKLVDLEEALQKAKQDMARLLREYQELMNIKLALDVEIAT 450
Query: 400 YRKLLEGEESRIS 412
YRKLLEGEE R+S
Sbjct: 451 YRKLLEGEECRLS 463
>gi|119395754 keratin 5 [Homo sapiens]
Length = 590
Score = 240 bits (612), Expect = 2e-63
Identities = 120/326 (36%), Positives = 208/326 (63%), Gaps = 5/326 (1%)
Query: 92 INTEFKNTRTNEKVELQELNDRFANYIDKVRFLEQQNKILLAELEQLKGQG----KSRLG 147
I+ + RT E+ +++ LN++FA++IDKVRFLEQQNK+L + L+ QG + L
Sbjct: 157 IDPSIQRVRTEEREQIKTLNNKFASFIDKVRFLEQQNKVLDTKWTLLQEQGTKTVRQNLE 216
Query: 148 DLYEEEMRELRRQVDQLTNDKARVEVERDNLAEDIMRLREKLQEEMLQREEAENTLQSFR 207
L+E+ + LRRQ+D + ++ R++ E N+ + + + K ++E+ +R AEN +
Sbjct: 217 PLFEQYINNLRRQLDSIVGERGRLDSELRNMQDLVEDFKNKYEDEINKRTTAENEFVMLK 276
Query: 208 QDVDNASLARLDLERKVESLQEEIAFLKKLHEEEIQELQAQIQEQHVQIDVDVSKP-DLT 266
+DVD A + +++LE KV++L +EI F+K + E+ ++Q + + V + +D ++ DL
Sbjct: 277 KDVDAAYMNKVELEAKVDALMDEINFMKMFFDAELSQMQTHVSDTSVVLSMDNNRNLDLD 336
Query: 267 AALRDVRQQYESVAAKNLQEAEEWYKSKFADLSEAANRNNDALRQAKQESTEYRRQVQSL 326
+ + +V+ QYE +A ++ EAE WY++K+ +L + A R+ D LR K E +E R +Q L
Sbjct: 337 SIIAEVKAQYEEIANRSRTEAESWYQTKYEELQQTAGRHGDDLRNTKHEISEMNRMIQRL 396
Query: 327 TCEVDALKGTNESLERQMREMEENFAVEAANYQDTIGRLQDEIQNMKEEMARHLREYQDL 386
E+D +K +L+ + + E+ + + ++ + L++ +Q K++MAR LREYQ+L
Sbjct: 397 RAEIDNVKKQCANLQNAIADAEQRGELALKDARNKLAELEEALQKAKQDMARLLREYQEL 456
Query: 387 LNVKMALDIEIATYRKLLEGEESRIS 412
+N K+ALD+EIATYRKLLEGEE R+S
Sbjct: 457 MNTKLALDVEIATYRKLLEGEECRLS 482
>gi|119395750 keratin 1 [Homo sapiens]
Length = 644
Score = 239 bits (610), Expect = 4e-63
Identities = 125/326 (38%), Positives = 214/326 (65%), Gaps = 5/326 (1%)
Query: 92 INTEFKNTRTNEKVELQELNDRFANYIDKVRFLEQQNKILLAELEQLKGQGKS----RLG 147
I+ E + ++ E+ +++ LN++FA++IDKVRFLEQQN++L + E L+ S L
Sbjct: 169 IDPEIQKVKSREREQIKSLNNQFASFIDKVRFLEQQNQVLQTKWELLQQVDTSTRTHNLE 228
Query: 148 DLYEEEMRELRRQVDQLTNDKARVEVERDNLAEDIMRLREKLQEEMLQREEAENTLQSFR 207
+E + LRR+VDQL +D++R++ E N+ + + R K ++E+ +R AEN + +
Sbjct: 229 PYFESFINNLRRRVDQLKSDQSRLDSELKNMQDMVEDYRNKYEDEINKRTNAENEFVTIK 288
Query: 208 QDVDNASLARLDLERKVESLQEEIAFLKKLHEEEIQELQAQIQEQHVQIDVDVSKP-DLT 266
+DVD A + ++DL+ K+++LQ+EI FL L++ E+ ++Q QI E +V + +D ++ DL
Sbjct: 289 KDVDGAYMTKVDLQAKLDNLQQEIDFLTALYQAELSQMQTQISETNVILSMDNNRSLDLD 348
Query: 267 AALRDVRQQYESVAAKNLQEAEEWYKSKFADLSEAANRNNDALRQAKQESTEYRRQVQSL 326
+ + +V+ QYE +A K+ EAE Y+SK+ +L A R+ D++R +K E +E R +Q L
Sbjct: 349 SIIAEVKAQYEDIAQKSKAEAESLYQSKYEELQITAGRHGDSVRNSKIEISELNRVIQRL 408
Query: 327 TCEVDALKGTNESLERQMREMEENFAVEAANYQDTIGRLQDEIQNMKEEMARHLREYQDL 386
E+D +K +L++ + + E+ + ++ + L+D +Q KE++AR LR+YQ+L
Sbjct: 409 RSEIDNVKKQISNLQQSISDAEQRGENALKDAKNKLNDLEDALQQAKEDLARLLRDYQEL 468
Query: 387 LNVKMALDIEIATYRKLLEGEESRIS 412
+N K+ALD+EIATYR LLEGEESR+S
Sbjct: 469 MNTKLALDLEIATYRTLLEGEESRMS 494
>gi|155969697 keratin 6C [Homo sapiens]
Length = 564
Score = 238 bits (608), Expect = 7e-63
Identities = 121/326 (37%), Positives = 210/326 (64%), Gaps = 5/326 (1%)
Query: 92 INTEFKNTRTNEKVELQELNDRFANYIDKVRFLEQQNKILLAELEQLKGQG----KSRLG 147
I+ + R E+ +++ LN++FA++IDKVRFLEQQNK+L + L+ QG + L
Sbjct: 152 IDPAIQRVRAEEREQIKTLNNKFASFIDKVRFLEQQNKVLDTKWTLLQEQGTKTVRQNLE 211
Query: 148 DLYEEEMRELRRQVDQLTNDKARVEVERDNLAEDIMRLREKLQEEMLQREEAENTLQSFR 207
L+E+ + LRRQ+D + ++ R++ E N+ + + L+ K ++E+ +R AEN + +
Sbjct: 212 PLFEQYINNLRRQLDSIVGERGRLDSELRNMQDLVEDLKNKYEDEINKRTAAENEFVTLK 271
Query: 208 QDVDNASLARLDLERKVESLQEEIAFLKKLHEEEIQELQAQIQEQHVQIDVDVSKP-DLT 266
+DVD A + +++L+ K ++L +EI FL+ L++ E+ ++Q I + V + +D ++ DL
Sbjct: 272 KDVDAAYMNKVELQAKADTLTDEINFLRALYDAELSQMQTHISDTSVVLSMDNNRNLDLD 331
Query: 267 AALRDVRQQYESVAAKNLQEAEEWYKSKFADLSEAANRNNDALRQAKQESTEYRRQVQSL 326
+ + +V+ QYE +A ++ EAE WY++K+ +L A R+ D LR KQE E R +Q L
Sbjct: 332 SIIAEVKAQYEEIAQRSRAEAESWYQTKYEELQVTAGRHGDDLRNTKQEIAEINRMIQRL 391
Query: 327 TCEVDALKGTNESLERQMREMEENFAVEAANYQDTIGRLQDEIQNMKEEMARHLREYQDL 386
E+D +K SL+ + + E+ + + ++ + L+D +Q K+++AR L+EYQ+L
Sbjct: 392 RSEIDHVKKQCASLQAAIADAEQRGEMALKDAKNKLEGLEDALQKAKQDLARLLKEYQEL 451
Query: 387 LNVKMALDIEIATYRKLLEGEESRIS 412
+NVK+ALD+EIATYRKLLEGEE R++
Sbjct: 452 MNVKLALDVEIATYRKLLEGEECRLN 477
>gi|119703753 keratin 6B [Homo sapiens]
Length = 564
Score = 237 bits (604), Expect = 2e-62
Identities = 120/326 (36%), Positives = 210/326 (64%), Gaps = 5/326 (1%)
Query: 92 INTEFKNTRTNEKVELQELNDRFANYIDKVRFLEQQNKILLAELEQLKGQG----KSRLG 147
I+ + R E+ +++ LN++FA++IDKVRFLEQQNK+L + L+ QG + L
Sbjct: 152 IDPAIQRVRAEEREQIKTLNNKFASFIDKVRFLEQQNKVLDTKWTLLQEQGTKTVRQNLE 211
Query: 148 DLYEEEMRELRRQVDQLTNDKARVEVERDNLAEDIMRLREKLQEEMLQREEAENTLQSFR 207
L+E+ + LRRQ+D + ++ R++ E N+ + + L+ K ++E+ +R AEN + +
Sbjct: 212 PLFEQYINNLRRQLDNIVGERGRLDSELRNMQDLVEDLKNKYEDEINKRTAAENEFVTLK 271
Query: 208 QDVDNASLARLDLERKVESLQEEIAFLKKLHEEEIQELQAQIQEQHVQIDVDVSKP-DLT 266
+DVD A + +++L+ K ++L +EI FL+ L++ E+ ++Q I + V + +D ++ DL
Sbjct: 272 KDVDAAYMNKVELQAKADTLTDEINFLRALYDAELSQMQTHISDTSVVLSMDNNRNLDLD 331
Query: 267 AALRDVRQQYESVAAKNLQEAEEWYKSKFADLSEAANRNNDALRQAKQESTEYRRQVQSL 326
+ + +V+ QYE +A ++ EAE WY++K+ +L A R+ D LR KQE E R +Q L
Sbjct: 332 SIIAEVKAQYEEIAQRSRAEAESWYQTKYEELQITAGRHGDDLRNTKQEIAEINRMIQRL 391
Query: 327 TCEVDALKGTNESLERQMREMEENFAVEAANYQDTIGRLQDEIQNMKEEMARHLREYQDL 386
E+D +K +L+ + + E+ + + ++ + L+D +Q K+++AR L+EYQ+L
Sbjct: 392 RSEIDHVKKQCANLQAAIADAEQRGEMALKDAKNKLEGLEDALQKAKQDLARLLKEYQEL 451
Query: 387 LNVKMALDIEIATYRKLLEGEESRIS 412
+NVK+ALD+EIATYRKLLEGEE R++
Sbjct: 452 MNVKLALDVEIATYRKLLEGEECRLN 477
>gi|15431316 keratin, hair, basic, 4 [Homo sapiens]
Length = 600
Score = 234 bits (597), Expect = 1e-61
Identities = 137/362 (37%), Positives = 218/362 (60%), Gaps = 12/362 (3%)
Query: 57 PGGVYATRSSAVRLRSSVPGVRLLQDSVDFSLADAINTEF----KNTRTNEKVELQELND 112
PG Y V S+ V +V+ SL +N E + + +EK +++ LN+
Sbjct: 120 PGFGYRVGGVGVPAAPSITAV-----TVNKSLLTPLNLEIDPNAQRVKKDEKEQIKTLNN 174
Query: 113 RFANYIDKVRFLEQQNKILLAELEQLKGQG--KSRLGDLYEEEMRELRRQVDQLTNDKAR 170
+FA++IDKVRFLEQQNK+L + L+ Q +S L L+E + LRRQ++ L +D+AR
Sbjct: 175 KFASFIDKVRFLEQQNKLLETKWSFLQEQKCIRSNLEPLFESYITNLRRQLEVLVSDQAR 234
Query: 171 VEVERDNLAEDIMRLREKLQEEMLQREEAENTLQSFRQDVDNASLARLDLERKVESLQEE 230
++ ER++L + + ++K +EE++ R AEN + ++DVD A + + DLE V++L +E
Sbjct: 235 LQAERNHLQDVLEGFKKKYEEEVVCRANAENEFVALKKDVDAAFMNKSDLEANVDTLTQE 294
Query: 231 IAFLKKLHEEEIQELQAQIQEQHVQIDVDVSKP-DLTAALRDVRQQYESVAAKNLQEAEE 289
I FLK L+ EEIQ LQ+ I E V + +D S+ +L + +V+ QYE VA ++ +AE
Sbjct: 295 IDFLKTLYMEEIQLLQSHISETSVIVKMDNSRDLNLDGIIAEVKAQYEEVARRSRADAEA 354
Query: 290 WYKSKFADLSEAANRNNDALRQAKQESTEYRRQVQSLTCEVDALKGTNESLERQMREMEE 349
WY++K+ ++ A ++ D LR + E E R +Q L E++ K LE + E E+
Sbjct: 355 WYQTKYEEMQVTAGQHCDNLRNIRNEINELTRLIQRLKAEIEHAKAQRAKLEAAVAEAEQ 414
Query: 350 NFAVEAANYQDTIGRLQDEIQNMKEEMARHLREYQDLLNVKMALDIEIATYRKLLEGEES 409
++ + + L+ +Q K++MAR L EYQ+L+N K+ LDIEIATYR+LLEGEES
Sbjct: 415 QGEATLSDAKCKLADLECALQQAKQDMARQLCEYQELMNAKLGLDIEIATYRRLLEGEES 474
Query: 410 RI 411
R+
Sbjct: 475 RL 476
>gi|5031839 keratin 6A [Homo sapiens]
Length = 564
Score = 234 bits (596), Expect = 2e-61
Identities = 118/326 (36%), Positives = 208/326 (63%), Gaps = 5/326 (1%)
Query: 92 INTEFKNTRTNEKVELQELNDRFANYIDKVRFLEQQNKILLAELEQLKGQG----KSRLG 147
I+ + R E+ +++ LN++FA++IDKVRFLEQQNK+L + L+ QG + L
Sbjct: 152 IDPTIQRVRAEEREQIKTLNNKFASFIDKVRFLEQQNKVLETKWTLLQEQGTKTVRQNLE 211
Query: 148 DLYEEEMRELRRQVDQLTNDKARVEVERDNLAEDIMRLREKLQEEMLQREEAENTLQSFR 207
L+E+ + LRRQ+D + ++ R++ E + + + + K ++E+ +R AEN + +
Sbjct: 212 PLFEQYINNLRRQLDSIVGERGRLDSELRGMQDLVEDFKNKYEDEINKRTAAENEFVTLK 271
Query: 208 QDVDNASLARLDLERKVESLQEEIAFLKKLHEEEIQELQAQIQEQHVQIDVDVSKP-DLT 266
+DVD A + +++L+ K ++L +EI FL+ L++ E+ ++Q I + V + +D ++ DL
Sbjct: 272 KDVDAAYMNKVELQAKADTLTDEINFLRALYDAELSQMQTHISDTSVVLSMDNNRNLDLD 331
Query: 267 AALRDVRQQYESVAAKNLQEAEEWYKSKFADLSEAANRNNDALRQAKQESTEYRRQVQSL 326
+ + +V+ QYE +A ++ EAE WY++K+ +L A R+ D LR KQE E R +Q L
Sbjct: 332 SIIAEVKAQYEEIAQRSRAEAESWYQTKYEELQVTAGRHGDDLRNTKQEIAEINRMIQRL 391
Query: 327 TCEVDALKGTNESLERQMREMEENFAVEAANYQDTIGRLQDEIQNMKEEMARHLREYQDL 386
E+D +K +L+ + + E+ + + ++ + L+D +Q K+++AR L+EYQ+L
Sbjct: 392 RSEIDHVKKQCANLQAAIADAEQRGEMALKDAKNKLEGLEDALQKAKQDLARLLKEYQEL 451
Query: 387 LNVKMALDIEIATYRKLLEGEESRIS 412
+NVK+ALD+EIATYRKLLEGEE R++
Sbjct: 452 MNVKLALDVEIATYRKLLEGEECRLN 477
>gi|109148552 keratin 3 [Homo sapiens]
Length = 628
Score = 231 bits (589), Expect = 1e-60
Identities = 125/359 (34%), Positives = 220/359 (61%), Gaps = 11/359 (3%)
Query: 83 SVDFSLADAINTEFK----NTRTNEKVELQELNDRFANYIDKVRFLEQQNKILLAELEQL 138
+++ SL +N E + E+ +++ LN++FA++IDKVRFLEQQNK+L + L
Sbjct: 174 TINQSLLQPLNVEIDPQIGQVKAQEREQIKTLNNKFASFIDKVRFLEQQNKVLETKWNLL 233
Query: 139 KGQGKS------RLGDLYEEEMRELRRQVDQLTNDKARVEVERDNLAEDIMRLREKLQEE 192
+ QG S L L+E + LR +D + ++ R++ E N+ + + ++K ++E
Sbjct: 234 QQQGTSSISGTNNLEPLFENHINYLRSYLDNILGERGRLDSELKNMEDLVEDFKKKYEDE 293
Query: 193 MLQREEAENTLQSFRQDVDNASLARLDLERKVESLQEEIAFLKKLHEEEIQELQAQIQEQ 252
+ +R AEN + ++DVD+A + +++L+ KV++L +EI FL+ L++ E+ ++Q+ I +
Sbjct: 294 INKRTAAENEFVTLKKDVDSAYMNKVELQAKVDALIDEIDFLRTLYDAELSQMQSHISDT 353
Query: 253 HVQIDVDVSKP-DLTAALRDVRQQYESVAAKNLQEAEEWYKSKFADLSEAANRNNDALRQ 311
V + +D ++ DL + + +VR QYE +A ++ EAE Y++K +L A R+ D LR
Sbjct: 354 SVVLSMDNNRSLDLDSIIAEVRAQYEDIAQRSKAEAEALYQTKLGELQTTAGRHGDDLRN 413
Query: 312 AKQESTEYRRQVQSLTCEVDALKGTNESLERQMREMEENFAVEAANYQDTIGRLQDEIQN 371
K E E R +Q L E++ +K N +L+ + E E++ + + + LQ +Q
Sbjct: 414 TKSEIIELNRMIQRLRAEIEGVKKQNANLQTAIAEAEQHGEMALKDANAKLQELQAALQQ 473
Query: 372 MKEEMARHLREYQDLLNVKMALDIEIATYRKLLEGEESRISLPLPNFSSLNLRETNLDS 430
K+++AR LR+YQ+L+NVK+ALD+EIATYRKLLEGEE R+S P+ S+++ ++ S
Sbjct: 474 AKDDLARLLRDYQELMNVKLALDVEIATYRKLLEGEEYRMSGECPSAVSISVVSSSTTS 532
>gi|32567786 keratin 6L [Homo sapiens]
Length = 535
Score = 230 bits (587), Expect = 2e-60
Identities = 124/339 (36%), Positives = 209/339 (61%), Gaps = 7/339 (2%)
Query: 92 INTEFKNTRTNEKVELQELNDRFANYIDKVRFLEQQNKILLAELEQLKGQG------KSR 145
I+ E + RT E+ +++ LN++FA++IDKVRFLEQQNK+L + L+ QG ++
Sbjct: 131 IDPEIQRVRTQEREQIKTLNNKFASFIDKVRFLEQQNKVLETKWALLQEQGQNLGVTRNN 190
Query: 146 LGDLYEEEMRELRRQVDQLTNDKARVEVERDNLAEDIMRLREKLQEEMLQREEAENTLQS 205
L L+E + +R +D+L +++ R++ E N+ + + + K ++E+ + AEN
Sbjct: 191 LEPLFEAYLGSMRSTLDRLQSERGRLDSELRNVQDLVEDFKNKYEDEINKHTAAENEFVV 250
Query: 206 FRQDVDNASLARLDLERKVESLQEEIAFLKKLHEEEIQELQAQIQEQHVQIDVDVSKP-D 264
++DVD A + R+DL KV +L +EI FL++L+E E+ ++Q + +V + +D ++ D
Sbjct: 251 LKKDVDAAYMGRMDLHGKVGTLTQEIDFLQQLYEMELSQVQTHVSNTNVVLSMDNNRNLD 310
Query: 265 LTAALRDVRQQYESVAAKNLQEAEEWYKSKFADLSEAANRNNDALRQAKQESTEYRRQVQ 324
L + + +V+ QYE +A ++ EAE WY++K+ +L A ++ D LR K E E R +Q
Sbjct: 311 LDSIIAEVKAQYELIAQRSRAEAEAWYQTKYEELQVTAGKHGDNLRDTKNEIAELTRTIQ 370
Query: 325 SLTCEVDALKGTNESLERQMREMEENFAVEAANYQDTIGRLQDEIQNMKEEMARHLREYQ 384
L E DA K + L+ + E E+ + + Q +G L + KE++ R LR+YQ
Sbjct: 371 RLQGEADAAKKQCQQLQTAIAEAEQRGELALKDAQKKLGDLDVALHQAKEDLTRLLRDYQ 430
Query: 385 DLLNVKMALDIEIATYRKLLEGEESRISLPLPNFSSLNL 423
+L+NVK+ALD+EIATYRKLLE EESR+S P+ S+++
Sbjct: 431 ELMNVKLALDVEIATYRKLLESEESRMSGECPSAVSISV 469
>gi|28173564 keratin 73 [Homo sapiens]
Length = 540
Score = 229 bits (585), Expect = 3e-60
Identities = 147/437 (33%), Positives = 248/437 (56%), Gaps = 17/437 (3%)
Query: 7 SSSSYRRMFGGPGTASRPSSSRSYVTTSTRTYSLGSALRPSTS------RSLYASSPGGV 60
SSSSYR GG G + SS Y R+ S A + R + G +
Sbjct: 28 SSSSYRA--GGKGLSGGFSSRSLYSLGGARSISFNVASGSGWAGGYGFGRGRASGFAGSM 85
Query: 61 YATRSSAVRLRSSVPGVRLLQDSVDFSLADAINTEF----KNTRTNEKVELQELNDRFAN 116
+ + + S P + Q +++ SL +N E + R E+ +++ LN++FA+
Sbjct: 86 FGSVALGSVCPSLCPPGGIHQVTINKSLLAPLNVELDPEIQKVRAQEREQIKVLNNKFAS 145
Query: 117 YIDKVRFLEQQNKILLAELEQLK----GQGKSRLGDLYEEEMRELRRQVDQLTNDKARVE 172
+IDKVRFLEQQN++L + E L+ K+ L + E + LR+Q++ L+ D+ R++
Sbjct: 146 FIDKVRFLEQQNQVLETKWELLQQLDLNNCKNNLEPILEGYISNLRKQLETLSGDRVRLD 205
Query: 173 VERDNLAEDIMRLREKLQEEMLQREEAENTLQSFRQDVDNASLARLDLERKVESLQEEIA 232
E ++ E + +++ +EE+ +R AEN ++DVD A ++++L+ KV++L EI
Sbjct: 206 SELRSVREVVEDYKKRYEEEINKRTTAENEFVVLKKDVDAAYTSKVELQAKVDALDGEIK 265
Query: 233 FLKKLHEEEIQELQAQIQEQHVQIDVDVSKP-DLTAALRDVRQQYESVAAKNLQEAEEWY 291
F K L+E E ++Q+ I + + + +D ++ DL + + +VR QYE +A K+ EAE Y
Sbjct: 266 FFKCLYEGETAQIQSHISDTSIILSMDNNRNLDLDSIIAEVRAQYEEIARKSKAEAEALY 325
Query: 292 KSKFADLSEAANRNNDALRQAKQESTEYRRQVQSLTCEVDALKGTNESLERQMREMEENF 351
++KF +L AA R+ D L+ K E +E R +Q L E++++K +LE + + E+
Sbjct: 326 QTKFQELQLAAGRHGDDLKHTKNEISELTRLIQRLRSEIESVKKQCANLETAIADAEQRG 385
Query: 352 AVEAANYQDTIGRLQDEIQNMKEEMARHLREYQDLLNVKMALDIEIATYRKLLEGEESRI 411
+ + + L+ +Q KEE+AR LREYQ+LL+VK++LDIEIATYRKLLEGEE R+
Sbjct: 386 DCALKDARAKLDELEGALQQAKEELARMLREYQELLSVKLSLDIEIATYRKLLEGEECRM 445
Query: 412 SLPLPNFSSLNLRETNL 428
S N S+++ +++
Sbjct: 446 SGEYTNSVSISVINSSM 462
>gi|109255249 keratin 4 [Homo sapiens]
Length = 594
Score = 225 bits (573), Expect = 8e-59
Identities = 124/326 (38%), Positives = 201/326 (61%), Gaps = 5/326 (1%)
Query: 92 INTEFKNTRTNEKVELQELNDRFANYIDKVRFLEQQNKILLAELEQLKGQ----GKSRLG 147
I+ E + RT E+ +++ LN++FA++IDKV+FLEQQNK+L + L+ Q L
Sbjct: 200 IDPEIQKVRTEEREQIKLLNNKFASFIDKVQFLEQQNKVLETKWNLLQQQTTTTSSKNLE 259
Query: 148 DLYEEEMRELRRQVDQLTNDKARVEVERDNLAEDIMRLREKLQEEMLQREEAENTLQSFR 207
L+E + LR+Q+D L NDK R++ E + + + + K +EE+ +R AEN +
Sbjct: 260 PLFETYLSVLRKQLDTLGNDKGRLQSELKTMQDSVEDFKTKYEEEINKRTAAENDFVVLK 319
Query: 208 QDVDNASLARLDLERKVESLQEEIAFLKKLHEEEIQELQAQIQEQHVQIDVDVSKP-DLT 266
+DVD A L +++LE KV+SL +EI FLK L++ E+ ++Q + + V + +D ++ DL
Sbjct: 320 KDVDAAYLNKVELEAKVDSLNDEINFLKVLYDAELSQMQTHVSDTSVVLSMDNNRNLDLD 379
Query: 267 AALRDVRQQYESVAAKNLQEAEEWYKSKFADLSEAANRNNDALRQAKQESTEYRRQVQSL 326
+ + +VR QYE +A ++ EAE Y++K L + +++ D L+ K E E R +Q L
Sbjct: 380 SIIAEVRAQYEEIAQRSKAEAEALYQTKVQQLQISVDQHGDNLKNTKSEIAELNRMIQRL 439
Query: 327 TCEVDALKGTNESLERQMREMEENFAVEAANYQDTIGRLQDEIQNMKEEMARHLREYQDL 386
E++ +K ++L+ + + E+ + L+ +Q KEE+AR LREYQ+L
Sbjct: 440 RAEIENIKKQCQTLQVSVADAEQRGENALKDAHSKRVELEAALQQAKEELARMLREYQEL 499
Query: 387 LNVKMALDIEIATYRKLLEGEESRIS 412
++VK+ALDIEIATYRKLLEGEE R+S
Sbjct: 500 MSVKLALDIEIATYRKLLEGEEYRMS 525
>gi|153791670 keratin 76 [Homo sapiens]
Length = 638
Score = 224 bits (572), Expect = 1e-58
Identities = 123/338 (36%), Positives = 207/338 (61%), Gaps = 9/338 (2%)
Query: 84 VDFSLADAINTEFK----NTRTNEKVELQELNDRFANYIDKVRFLEQQNKILLAELEQLK 139
V+ SL +N E + E+ +++ LN++FA++IDKVRFLEQQNK+L + E L+
Sbjct: 160 VNQSLLQPLNVEIDPQIGQVKAQEREQIKTLNNKFASFIDKVRFLEQQNKVLETKWELLQ 219
Query: 140 ----GQGKSRLGDLYEEEMRELRRQVDQLTNDKARVEVERDNLAEDIMRLREKLQEEMLQ 195
G G S L +E + L +Q+D L ++ +E E ++ + + ++K ++E+ +
Sbjct: 220 QQTTGSGPSSLEPCFESYISFLCKQLDSLLGERGNLEGELKSMQDLVEDFKKKYEDEINK 279
Query: 196 REEAENTLQSFRQDVDNASLARLDLERKVESLQEEIAFLKKLHEEEIQELQAQIQEQHVQ 255
R AEN ++DVD A + +++L+ KV+SL +E++FL+ L+E E+ ++Q+ + V
Sbjct: 280 RTAAENEFVGLKKDVDAAFMNKVELQAKVDSLTDEVSFLRTLYEMELSQMQSHASDTSVV 339
Query: 256 IDVDVSKP-DLTAALRDVRQQYESVAAKNLQEAEEWYKSKFADLSEAANRNNDALRQAKQ 314
+ +D ++ DL + + +VR QYE +A ++ EAE Y++K +L A R+ D LR K
Sbjct: 340 LSMDNNRCLDLGSIIAEVRAQYEEIAQRSKSEAEALYQTKLGELQTTAGRHGDDLRNTKS 399
Query: 315 ESTEYRRQVQSLTCEVDALKGTNESLERQMREMEENFAVEAANYQDTIGRLQDEIQNMKE 374
E E R +Q L E++ +K N +L+ + E E+ + + + LQ +Q K+
Sbjct: 400 EIMELNRMIQRLRAEIENVKKQNANLQTAIAEAEQRGEMALKDANAKLQDLQTALQKAKD 459
Query: 375 EMARHLREYQDLLNVKMALDIEIATYRKLLEGEESRIS 412
++AR LR+YQ+L+NVK+ALD+EIATYRKLLEGEE R+S
Sbjct: 460 DLARLLRDYQELMNVKLALDVEIATYRKLLEGEECRMS 497
>gi|15618995 keratin 71 [Homo sapiens]
Length = 523
Score = 224 bits (570), Expect = 2e-58
Identities = 143/430 (33%), Positives = 240/430 (55%), Gaps = 15/430 (3%)
Query: 7 SSSSYRRMFGGPGTASRPSSSRSYVTTSTRTYSLGSALRPSTSRSLYASSPGGVYATRSS 66
SSSS+R G G + S Y R+ ++ S S G +
Sbjct: 28 SSSSFRA--GSKGLSGGFGSRSLYSLGGVRSLNVASGSGKSGGYGFGRGRASGFAGSMFG 85
Query: 67 AVRLRSSVPGV----RLLQDSVDFSLADAINTEF----KNTRTNEKVELQELNDRFANYI 118
+V L P V + Q +V+ SL +N E + R E+ +++ LN++FA++I
Sbjct: 86 SVALGPVCPTVCPPGGIHQVTVNESLLAPLNVELDPEIQKVRAQEREQIKALNNKFASFI 145
Query: 119 DKVRFLEQQNKILLAELEQLK----GQGKSRLGDLYEEEMRELRRQVDQLTNDKARVEVE 174
DKVRFLEQQN++L + E L+ K+ L + E + LR+Q++ L+ D+ R++ E
Sbjct: 146 DKVRFLEQQNQVLETKWELLQQLDLNNCKNNLEPILEGYISNLRKQLETLSGDRVRLDSE 205
Query: 175 RDNLAEDIMRLREKLQEEMLQREEAENTLQSFRQDVDNASLARLDLERKVESLQEEIAFL 234
N+ + + +++ +EE+ +R AEN ++DVD A +++L+ KVES+ +EI F
Sbjct: 206 LRNVRDVVEDYKKRYEEEINKRTAAENEFVLLKKDVDAAYANKVELQAKVESMDQEIKFF 265
Query: 235 KKLHEEEIQELQAQIQEQHVQIDVDVSKP-DLTAALRDVRQQYESVAAKNLQEAEEWYKS 293
+ L E EI ++Q+ I + V + +D ++ DL + + +VR QYE +A K+ EAE Y++
Sbjct: 266 RCLFEAEITQIQSHISDMSVILSMDNNRNLDLDSIIDEVRTQYEEIALKSKAEAEALYQT 325
Query: 294 KFADLSEAANRNNDALRQAKQESTEYRRQVQSLTCEVDALKGTNESLERQMREMEENFAV 353
KF +L AA R+ D L+ K E +E R +Q + E++ +K +LE + + E+
Sbjct: 326 KFQELQLAAGRHGDDLKNTKNEISELTRLIQRIRSEIENVKKQASNLETAIADAEQRGDN 385
Query: 354 EAANYQDTIGRLQDEIQNMKEEMARHLREYQDLLNVKMALDIEIATYRKLLEGEESRISL 413
+ + + L+ + KEE+AR LREYQ+L+++K+ALD+EIATYRKLLE EE R+S
Sbjct: 386 ALKDARAKLDELEGALHQAKEELARMLREYQELMSLKLALDMEIATYRKLLESEECRMSG 445
Query: 414 PLPNFSSLNL 423
P+ S+++
Sbjct: 446 EFPSPVSISI 455
>gi|239755818 PREDICTED: hypothetical protein isoform 2 [Homo
sapiens]
Length = 486
Score = 221 bits (564), Expect = 8e-58
Identities = 124/336 (36%), Positives = 204/336 (60%), Gaps = 7/336 (2%)
Query: 83 SVDFSLADAINTEF----KNTRTNEKVELQELNDRFANYIDKVRFLEQQNKILLAELEQL 138
SV+ SL +N E + + EK +++ LN RFA +IDKVRFLEQQNK+L +L+
Sbjct: 82 SVNESLLTPLNLEIDPNAQCVKQEEKEQIKSLNSRFAAFIDKVRFLEQQNKLLETKLQFY 141
Query: 139 KGQG--KSRLGDLYEEEMRELRRQVDQLTNDKARVEVERDNLAEDIMRLREKLQEEMLQR 196
+ + +S L L+E + LRR+ + + D R+ E +++ E + ++K +EE+ R
Sbjct: 142 QNRECCQSNLEPLFEGYIETLRREAECVEADSGRLASELNHVQEVLEGYKKKYEEEVSLR 201
Query: 197 EEAENTLQSFRQDVDNASLARLDLERKVESLQEEIAFLKKLHEEEIQELQAQIQEQHVQI 256
AEN + ++DVD A L + DLE VE+L +EI FL++L+EEEI+ LQ+ I + V +
Sbjct: 202 ATAENEFVALKKDVDCAYLRKSDLEANVEALIQEIDFLRRLYEEEIRVLQSHISDTSVVV 261
Query: 257 DVDVSKP-DLTAALRDVRQQYESVAAKNLQEAEEWYKSKFADLSEAANRNNDALRQAKQE 315
+D S+ ++ + +++ QY+ + ++ EAE WY+SK ++ R+ + LR+ K+E
Sbjct: 262 KLDNSRDLNMDCIIAEIKAQYDDIVTRSRAEAESWYRSKCEEMKATVIRHGETLRRTKEE 321
Query: 316 STEYRRQVQSLTCEVDALKGTNESLERQMREMEENFAVEAANYQDTIGRLQDEIQNMKEE 375
E R +Q LT EV+ K N LE + + E+ ++ + + L+ +Q K++
Sbjct: 322 INELNRMIQRLTAEVENAKCQNSKLEAAVAQSEQQGEAALSDARCKLAELEGALQKAKQD 381
Query: 376 MARHLREYQDLLNVKMALDIEIATYRKLLEGEESRI 411
MA +REYQ+++N K+ LDIEIATYR+LLEGEE R+
Sbjct: 382 MACLIREYQEVMNSKLGLDIEIATYRRLLEGEEQRL 417
>gi|239755816 PREDICTED: hypothetical protein isoform 1 [Homo
sapiens]
Length = 486
Score = 221 bits (564), Expect = 8e-58
Identities = 124/336 (36%), Positives = 204/336 (60%), Gaps = 7/336 (2%)
Query: 83 SVDFSLADAINTEF----KNTRTNEKVELQELNDRFANYIDKVRFLEQQNKILLAELEQL 138
SV+ SL +N E + + EK +++ LN RFA +IDKVRFLEQQNK+L +L+
Sbjct: 82 SVNESLLTPLNLEIDPNAQCVKQEEKEQIKSLNSRFAAFIDKVRFLEQQNKLLETKLQFY 141
Query: 139 KGQG--KSRLGDLYEEEMRELRRQVDQLTNDKARVEVERDNLAEDIMRLREKLQEEMLQR 196
+ + +S L L+E + LRR+ + + D R+ E +++ E + ++K +EE+ R
Sbjct: 142 QNRECCQSNLEPLFEGYIETLRREAECVEADSGRLASELNHVQEVLEGYKKKYEEEVSLR 201
Query: 197 EEAENTLQSFRQDVDNASLARLDLERKVESLQEEIAFLKKLHEEEIQELQAQIQEQHVQI 256
AEN + ++DVD A L + DLE VE+L +EI FL++L+EEEI+ LQ+ I + V +
Sbjct: 202 ATAENEFVALKKDVDCAYLRKSDLEANVEALIQEIDFLRRLYEEEIRVLQSHISDTSVVV 261
Query: 257 DVDVSKP-DLTAALRDVRQQYESVAAKNLQEAEEWYKSKFADLSEAANRNNDALRQAKQE 315
+D S+ ++ + +++ QY+ + ++ EAE WY+SK ++ R+ + LR+ K+E
Sbjct: 262 KLDNSRDLNMDCIIAEIKAQYDDIVTRSRAEAESWYRSKCEEMKATVIRHGETLRRTKEE 321
Query: 316 STEYRRQVQSLTCEVDALKGTNESLERQMREMEENFAVEAANYQDTIGRLQDEIQNMKEE 375
E R +Q LT EV+ K N LE + + E+ ++ + + L+ +Q K++
Sbjct: 322 INELNRMIQRLTAEVENAKCQNSKLEAAVAQSEQQGEAALSDARCKLAELEGALQKAKQD 381
Query: 376 MARHLREYQDLLNVKMALDIEIATYRKLLEGEESRI 411
MA +REYQ+++N K+ LDIEIATYR+LLEGEE R+
Sbjct: 382 MACLIREYQEVMNSKLGLDIEIATYRRLLEGEEQRL 417
>gi|239755814 PREDICTED: hypothetical protein isoform 3 [Homo
sapiens]
Length = 486
Score = 221 bits (564), Expect = 8e-58
Identities = 124/336 (36%), Positives = 204/336 (60%), Gaps = 7/336 (2%)
Query: 83 SVDFSLADAINTEF----KNTRTNEKVELQELNDRFANYIDKVRFLEQQNKILLAELEQL 138
SV+ SL +N E + + EK +++ LN RFA +IDKVRFLEQQNK+L +L+
Sbjct: 82 SVNESLLTPLNLEIDPNAQCVKQEEKEQIKSLNSRFAAFIDKVRFLEQQNKLLETKLQFY 141
Query: 139 KGQG--KSRLGDLYEEEMRELRRQVDQLTNDKARVEVERDNLAEDIMRLREKLQEEMLQR 196
+ + +S L L+E + LRR+ + + D R+ E +++ E + ++K +EE+ R
Sbjct: 142 QNRECCQSNLEPLFEGYIETLRREAECVEADSGRLASELNHVQEVLEGYKKKYEEEVSLR 201
Query: 197 EEAENTLQSFRQDVDNASLARLDLERKVESLQEEIAFLKKLHEEEIQELQAQIQEQHVQI 256
AEN + ++DVD A L + DLE VE+L +EI FL++L+EEEI+ LQ+ I + V +
Sbjct: 202 ATAENEFVALKKDVDCAYLRKSDLEANVEALIQEIDFLRRLYEEEIRVLQSHISDTSVVV 261
Query: 257 DVDVSKP-DLTAALRDVRQQYESVAAKNLQEAEEWYKSKFADLSEAANRNNDALRQAKQE 315
+D S+ ++ + +++ QY+ + ++ EAE WY+SK ++ R+ + LR+ K+E
Sbjct: 262 KLDNSRDLNMDCIIAEIKAQYDDIVTRSRAEAESWYRSKCEEMKATVIRHGETLRRTKEE 321
Query: 316 STEYRRQVQSLTCEVDALKGTNESLERQMREMEENFAVEAANYQDTIGRLQDEIQNMKEE 375
E R +Q LT EV+ K N LE + + E+ ++ + + L+ +Q K++
Sbjct: 322 INELNRMIQRLTAEVENAKCQNSKLEAAVAQSEQQGEAALSDARCKLAELEGALQKAKQD 381
Query: 376 MARHLREYQDLLNVKMALDIEIATYRKLLEGEESRI 411
MA +REYQ+++N K+ LDIEIATYR+LLEGEE R+
Sbjct: 382 MACLIREYQEVMNSKLGLDIEIATYRRLLEGEEQRL 417
>gi|14318422 keratin 86 [Homo sapiens]
Length = 486
Score = 221 bits (564), Expect = 8e-58
Identities = 124/336 (36%), Positives = 204/336 (60%), Gaps = 7/336 (2%)
Query: 83 SVDFSLADAINTEF----KNTRTNEKVELQELNDRFANYIDKVRFLEQQNKILLAELEQL 138
SV+ SL +N E + + EK +++ LN RFA +IDKVRFLEQQNK+L +L+
Sbjct: 82 SVNESLLTPLNLEIDPNAQCVKQEEKEQIKSLNSRFAAFIDKVRFLEQQNKLLETKLQFY 141
Query: 139 KGQG--KSRLGDLYEEEMRELRRQVDQLTNDKARVEVERDNLAEDIMRLREKLQEEMLQR 196
+ + +S L L+E + LRR+ + + D R+ E +++ E + ++K +EE+ R
Sbjct: 142 QNRECCQSNLEPLFEGYIETLRREAECVEADSGRLASELNHVQEVLEGYKKKYEEEVSLR 201
Query: 197 EEAENTLQSFRQDVDNASLARLDLERKVESLQEEIAFLKKLHEEEIQELQAQIQEQHVQI 256
AEN + ++DVD A L + DLE VE+L +EI FL++L+EEEI+ LQ+ I + V +
Sbjct: 202 ATAENEFVALKKDVDCAYLRKSDLEANVEALIQEIDFLRRLYEEEIRVLQSHISDTSVVV 261
Query: 257 DVDVSKP-DLTAALRDVRQQYESVAAKNLQEAEEWYKSKFADLSEAANRNNDALRQAKQE 315
+D S+ ++ + +++ QY+ + ++ EAE WY+SK ++ R+ + LR+ K+E
Sbjct: 262 KLDNSRDLNMDCIIAEIKAQYDDIVTRSRAEAESWYRSKCEEMKATVIRHGETLRRTKEE 321
Query: 316 STEYRRQVQSLTCEVDALKGTNESLERQMREMEENFAVEAANYQDTIGRLQDEIQNMKEE 375
E R +Q LT EV+ K N LE + + E+ ++ + + L+ +Q K++
Sbjct: 322 INELNRMIQRLTAEVENAKCQNSKLEAAVAQSEQQGEAALSDARCKLAELEGALQKAKQD 381
Query: 376 MARHLREYQDLLNVKMALDIEIATYRKLLEGEESRI 411
MA +REYQ+++N K+ LDIEIATYR+LLEGEE R+
Sbjct: 382 MACLIREYQEVMNSKLGLDIEIATYRRLLEGEEQRL 417
>gi|169790841 keratin 83 [Homo sapiens]
Length = 493
Score = 220 bits (561), Expect = 2e-57
Identities = 124/336 (36%), Positives = 204/336 (60%), Gaps = 7/336 (2%)
Query: 83 SVDFSLADAINTEF----KNTRTNEKVELQELNDRFANYIDKVRFLEQQNKILLAELEQL 138
SV+ SL +N E + + EK +++ LN RFA +IDKVRFLEQQNK+L +L+
Sbjct: 87 SVNESLLTPLNLEIDPNAQCVKQEEKEQIKSLNSRFAAFIDKVRFLEQQNKLLETKLQFY 146
Query: 139 KGQG--KSRLGDLYEEEMRELRRQVDQLTNDKARVEVERDNLAEDIMRLREKLQEEMLQR 196
+ + +S L L+ + LRR+ + + D R+ E +++ E + ++K +EE+ R
Sbjct: 147 QNRECCQSNLEPLFAGYIETLRREAECVEADSGRLASELNHVQEVLEGYKKKYEEEVALR 206
Query: 197 EEAENTLQSFRQDVDNASLARLDLERKVESLQEEIAFLKKLHEEEIQELQAQIQEQHVQI 256
AEN + ++DVD A L + DLE VE+L +EI FL++L+EEEI+ LQ+ I + V +
Sbjct: 207 ATAENEFVALKKDVDCAYLRKSDLEANVEALIQEIDFLRRLYEEEIRILQSHISDTSVVV 266
Query: 257 DVDVSKP-DLTAALRDVRQQYESVAAKNLQEAEEWYKSKFADLSEAANRNNDALRQAKQE 315
+D S+ ++ + +++ QY+ +A ++ EAE WY+SK ++ R+ + LR+ K+E
Sbjct: 267 KLDNSRDLNMDCIVAEIKAQYDDIATRSRAEAESWYRSKCEEMKATVIRHGETLRRTKEE 326
Query: 316 STEYRRQVQSLTCEVDALKGTNESLERQMREMEENFAVEAANYQDTIGRLQDEIQNMKEE 375
E R +Q LT EV+ K N LE + + E+ ++ + + L+ +Q K++
Sbjct: 327 INELNRMIQRLTAEVENAKCQNSKLEAAVAQSEQQGEAALSDARCKLAELEGALQKAKQD 386
Query: 376 MARHLREYQDLLNVKMALDIEIATYRKLLEGEESRI 411
MA +REYQ+++N K+ LDIEIATYR+LLEGEE R+
Sbjct: 387 MACLIREYQEVMNSKLGLDIEIATYRRLLEGEEQRL 422
>gi|148612803 keratin 6 irs4 [Homo sapiens]
Length = 529
Score = 220 bits (560), Expect = 2e-57
Identities = 129/375 (34%), Positives = 219/375 (58%), Gaps = 9/375 (2%)
Query: 58 GGVYATRSSAVRLRSSVPGVRLLQDSVDFSLADAINTEF----KNTRTNEKVELQELNDR 113
G ++ + + S P + Q +V+ SL +N E + R E+ +++ LND+
Sbjct: 91 GSMFGSVALGPACLSVCPPGGIHQVTVNKSLLAPLNVELDPEIQKVRAQEREQIKVLNDK 150
Query: 114 FANYIDKVRFLEQQNKILLAELEQLK----GQGKSRLGDLYEEEMRELRRQVDQLTNDKA 169
FA++IDKVRFLEQQN++L + E L+ K L + E + LR+Q++ L+ D+
Sbjct: 151 FASFIDKVRFLEQQNQVLETKWELLQQLDLNNCKKNLEPILEGYISNLRKQLETLSGDRV 210
Query: 170 RVEVERDNLAEDIMRLREKLQEEMLQREEAENTLQSFRQDVDNASLARLDLERKVESLQE 229
R++ E ++ + + +++ + E+ +R AEN ++D D A +++L+ KV+SL +
Sbjct: 211 RLDSELRSMRDLVEDYKKRYEVEINRRTTAENEFVVLKKDADAAYAVKVELQAKVDSLDK 270
Query: 230 EIAFLKKLHEEEIQELQAQIQEQHVQIDVDVSKP-DLTAALRDVRQQYESVAAKNLQEAE 288
EI FLK L++ EI ++Q E V + +D ++ DL + + +VR YE +A K+ EAE
Sbjct: 271 EIKFLKCLYDAEIAQIQTHASETSVILSMDNNRDLDLDSIIAEVRMHYEEIALKSKAEAE 330
Query: 289 EWYKSKFADLSEAANRNNDALRQAKQESTEYRRQVQSLTCEVDALKGTNESLERQMREME 348
Y++K +L AA+R+ D L+ + E E R +Q + CE+ +K SLE + + E
Sbjct: 331 ALYQTKIQELQLAASRHGDDLKHTRSEMVELNRLIQRIRCEIGNVKKQRASLETAIADAE 390
Query: 349 ENFAVEAANYQDTIGRLQDEIQNMKEEMARHLREYQDLLNVKMALDIEIATYRKLLEGEE 408
+ + Q + L+ + KEE+AR LREYQ+L+++K+ALD+EIATYRKLLEGEE
Sbjct: 391 QRGDNALKDAQAKLDELEGALHQAKEELARMLREYQELMSLKLALDMEIATYRKLLEGEE 450
Query: 409 SRISLPLPNFSSLNL 423
R+S P+ S+++
Sbjct: 451 CRMSGENPSSVSISV 465
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.311 0.126 0.329
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 14,871,531
Number of Sequences: 37866
Number of extensions: 650418
Number of successful extensions: 9961
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 354
Number of HSP's successfully gapped in prelim test: 903
Number of HSP's that attempted gapping in prelim test: 4371
Number of HSP's gapped (non-prelim): 3433
length of query: 466
length of database: 18,247,518
effective HSP length: 106
effective length of query: 360
effective length of database: 14,233,722
effective search space: 5124139920
effective search space used: 5124139920
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.