Search of human proteins with 62240994

Search of human proteins with 62240994

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|62240994 cysteinyl-tRNA synthetase isoform d [Homo sapiens]
         (738 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|62240994 cysteinyl-tRNA synthetase isoform d [Homo sapiens]       1491   0.0  
gi|62240992 cysteinyl-tRNA synthetase isoform c [Homo sapiens]       1436   0.0  
gi|10835051 cysteinyl-tRNA synthetase isoform b [Homo sapiens]       1436   0.0  
gi|21269877 cysteinyl-tRNA synthetase isoform a [Homo sapiens]       1348   0.0  
gi|13375695 cysteinyl-tRNA synthetase 2, mitochondrial [Homo sap...   241   2e-63
gi|11693132 UPF2 regulator of nonsense transcripts homolog [Homo...    45   2e-04
gi|18375676 UPF2 regulator of nonsense transcripts homolog [Homo...    45   2e-04
gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-li...    43   0.001
gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-li...    42   0.002
gi|15149465 caldesmon 1 isoform 5 [Homo sapiens]                       42   0.003
gi|15149463 caldesmon 1 isoform 4 [Homo sapiens]                       42   0.003
gi|15149467 caldesmon 1 isoform 3 [Homo sapiens]                       42   0.003
gi|4826657 caldesmon 1 isoform 2 [Homo sapiens]                        42   0.003
gi|44680105 caldesmon 1 isoform 1 [Homo sapiens]                       42   0.003
gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo sap...    41   0.003
gi|151301171 RNA polymerase II transcription factor TAFII140 [Ho...    41   0.003
gi|71061468 centromere protein E [Homo sapiens]                        41   0.003
gi|22035606 mitogen-activated protein kinase kinase kinase kinas...    41   0.003
gi|22035602 mitogen-activated protein kinase kinase kinase kinas...    41   0.003
gi|22035604 mitogen-activated protein kinase kinase kinase kinas...    41   0.003
gi|239508778 PREDICTED: hypothetical protein, partial [Homo sapi...    41   0.005
gi|12711676 UPF3 regulator of nonsense transcripts homolog A iso...    40   0.010
gi|18375525 UPF3 regulator of nonsense transcripts homolog A iso...    40   0.010
gi|15826852 acyl-Coenzyme A binding domain containing 3 [Homo sa...    39   0.013
gi|102467235 inner centromere protein antigens 135/155kDa isofor...    39   0.013
gi|102467242 inner centromere protein antigens 135/155kDa isofor...    39   0.013
gi|108773810 leucyl-tRNA synthetase [Homo sapiens]                     39   0.017
gi|50513245 chromatin assembly factor 1, subunit A (p150) [Homo ...    39   0.017
gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo sa...    39   0.023
gi|223634475 golgi autoantigen, golgin subfamily a, 6D [Homo sap...    38   0.030

>gi|62240994 cysteinyl-tRNA synthetase isoform d [Homo sapiens]
          Length = 738

 Score = 1491 bits (3859), Expect = 0.0
 Identities = 738/738 (100%), Positives = 738/738 (100%)

Query: 1   MQTPPLQQPHQEQVFLAFLVIVIPSFLTKEVFIPQDGKKVTWYCCGPTVYDASHMGHARS 60
           MQTPPLQQPHQEQVFLAFLVIVIPSFLTKEVFIPQDGKKVTWYCCGPTVYDASHMGHARS
Sbjct: 1   MQTPPLQQPHQEQVFLAFLVIVIPSFLTKEVFIPQDGKKVTWYCCGPTVYDASHMGHARS 60

Query: 61  YISFDILRRVLKDYFKFDVFYCMNITDIDDKIIKRARQNHLFEQYREKRPEAAQLLEDVQ 120
           YISFDILRRVLKDYFKFDVFYCMNITDIDDKIIKRARQNHLFEQYREKRPEAAQLLEDVQ
Sbjct: 61  YISFDILRRVLKDYFKFDVFYCMNITDIDDKIIKRARQNHLFEQYREKRPEAAQLLEDVQ 120

Query: 121 AALKPFSVKLNETTDPDKKQMLERIQHAVQLATEPLEKAVQSRLTGEEVNSCVEVLLEEA 180
           AALKPFSVKLNETTDPDKKQMLERIQHAVQLATEPLEKAVQSRLTGEEVNSCVEVLLEEA
Sbjct: 121 AALKPFSVKLNETTDPDKKQMLERIQHAVQLATEPLEKAVQSRLTGEEVNSCVEVLLEEA 180

Query: 181 KDLLSDWLDSTLGCDVTDNSIFSKLPKFWEGDFHRDMEALNVLPPDVLTRVSEYVPEIVN 240
           KDLLSDWLDSTLGCDVTDNSIFSKLPKFWEGDFHRDMEALNVLPPDVLTRVSEYVPEIVN
Sbjct: 181 KDLLSDWLDSTLGCDVTDNSIFSKLPKFWEGDFHRDMEALNVLPPDVLTRVSEYVPEIVN 240

Query: 241 FVQKIVDNGYGYVSNGSVYFDTAKFASSEKHSYGKLVPEAVGDQKALQEGEGDLSISADR 300
           FVQKIVDNGYGYVSNGSVYFDTAKFASSEKHSYGKLVPEAVGDQKALQEGEGDLSISADR
Sbjct: 241 FVQKIVDNGYGYVSNGSVYFDTAKFASSEKHSYGKLVPEAVGDQKALQEGEGDLSISADR 300

Query: 301 LSEKRSPNDFALWKASKPGEPSWPCPWGKGRPGWHIECSAMAGTLLGASMDIHGGGFDLR 360
           LSEKRSPNDFALWKASKPGEPSWPCPWGKGRPGWHIECSAMAGTLLGASMDIHGGGFDLR
Sbjct: 301 LSEKRSPNDFALWKASKPGEPSWPCPWGKGRPGWHIECSAMAGTLLGASMDIHGGGFDLR 360

Query: 361 FPHHDNELAQSEAYFENDCWVRYFLHTGHLTIAGCKMSKSLKNFITIKDALKKHSARQLR 420
           FPHHDNELAQSEAYFENDCWVRYFLHTGHLTIAGCKMSKSLKNFITIKDALKKHSARQLR
Sbjct: 361 FPHHDNELAQSEAYFENDCWVRYFLHTGHLTIAGCKMSKSLKNFITIKDALKKHSARQLR 420

Query: 421 LAFLMHSWKDTLDYSSNTMESALQYEKFLNEFFLNVKDILRAPVDITGQFEKWGEEEAEL 480
           LAFLMHSWKDTLDYSSNTMESALQYEKFLNEFFLNVKDILRAPVDITGQFEKWGEEEAEL
Sbjct: 421 LAFLMHSWKDTLDYSSNTMESALQYEKFLNEFFLNVKDILRAPVDITGQFEKWGEEEAEL 480

Query: 481 NKNFYDKKTAIHKALCDNVDTRTVMEEMRALVSQCNLYMAARKAVRKRPNQALLENIALY 540
           NKNFYDKKTAIHKALCDNVDTRTVMEEMRALVSQCNLYMAARKAVRKRPNQALLENIALY
Sbjct: 481 NKNFYDKKTAIHKALCDNVDTRTVMEEMRALVSQCNLYMAARKAVRKRPNQALLENIALY 540

Query: 541 LTHMLKIFGAVEEDSSLGFPVGGPGTSLSLEATVMPYLQVLSEFREGVRKIAREQKVPEI 600
           LTHMLKIFGAVEEDSSLGFPVGGPGTSLSLEATVMPYLQVLSEFREGVRKIAREQKVPEI
Sbjct: 541 LTHMLKIFGAVEEDSSLGFPVGGPGTSLSLEATVMPYLQVLSEFREGVRKIAREQKVPEI 600

Query: 601 LQLSDALRDNILPELGVRFEDHEGLPTVVKLVDRNTLLKEREEKRRVEEEKRKKKEEAAR 660
           LQLSDALRDNILPELGVRFEDHEGLPTVVKLVDRNTLLKEREEKRRVEEEKRKKKEEAAR
Sbjct: 601 LQLSDALRDNILPELGVRFEDHEGLPTVVKLVDRNTLLKEREEKRRVEEEKRKKKEEAAR 660

Query: 661 RKQEQEAAKLAKMKIPPSEMFLSETDKYSKFDENGLPTHDMEGKELSKGQAKKLKKLFEA 720
           RKQEQEAAKLAKMKIPPSEMFLSETDKYSKFDENGLPTHDMEGKELSKGQAKKLKKLFEA
Sbjct: 661 RKQEQEAAKLAKMKIPPSEMFLSETDKYSKFDENGLPTHDMEGKELSKGQAKKLKKLFEA 720

Query: 721 QEKLYKEYLQMAQNGSFQ 738
           QEKLYKEYLQMAQNGSFQ
Sbjct: 721 QEKLYKEYLQMAQNGSFQ 738


>gi|62240992 cysteinyl-tRNA synthetase isoform c [Homo sapiens]
          Length = 831

 Score = 1436 bits (3716), Expect = 0.0
 Identities = 710/710 (100%), Positives = 710/710 (100%)

Query: 29  KEVFIPQDGKKVTWYCCGPTVYDASHMGHARSYISFDILRRVLKDYFKFDVFYCMNITDI 88
           KEVFIPQDGKKVTWYCCGPTVYDASHMGHARSYISFDILRRVLKDYFKFDVFYCMNITDI
Sbjct: 122 KEVFIPQDGKKVTWYCCGPTVYDASHMGHARSYISFDILRRVLKDYFKFDVFYCMNITDI 181

Query: 89  DDKIIKRARQNHLFEQYREKRPEAAQLLEDVQAALKPFSVKLNETTDPDKKQMLERIQHA 148
           DDKIIKRARQNHLFEQYREKRPEAAQLLEDVQAALKPFSVKLNETTDPDKKQMLERIQHA
Sbjct: 182 DDKIIKRARQNHLFEQYREKRPEAAQLLEDVQAALKPFSVKLNETTDPDKKQMLERIQHA 241

Query: 149 VQLATEPLEKAVQSRLTGEEVNSCVEVLLEEAKDLLSDWLDSTLGCDVTDNSIFSKLPKF 208
           VQLATEPLEKAVQSRLTGEEVNSCVEVLLEEAKDLLSDWLDSTLGCDVTDNSIFSKLPKF
Sbjct: 242 VQLATEPLEKAVQSRLTGEEVNSCVEVLLEEAKDLLSDWLDSTLGCDVTDNSIFSKLPKF 301

Query: 209 WEGDFHRDMEALNVLPPDVLTRVSEYVPEIVNFVQKIVDNGYGYVSNGSVYFDTAKFASS 268
           WEGDFHRDMEALNVLPPDVLTRVSEYVPEIVNFVQKIVDNGYGYVSNGSVYFDTAKFASS
Sbjct: 302 WEGDFHRDMEALNVLPPDVLTRVSEYVPEIVNFVQKIVDNGYGYVSNGSVYFDTAKFASS 361

Query: 269 EKHSYGKLVPEAVGDQKALQEGEGDLSISADRLSEKRSPNDFALWKASKPGEPSWPCPWG 328
           EKHSYGKLVPEAVGDQKALQEGEGDLSISADRLSEKRSPNDFALWKASKPGEPSWPCPWG
Sbjct: 362 EKHSYGKLVPEAVGDQKALQEGEGDLSISADRLSEKRSPNDFALWKASKPGEPSWPCPWG 421

Query: 329 KGRPGWHIECSAMAGTLLGASMDIHGGGFDLRFPHHDNELAQSEAYFENDCWVRYFLHTG 388
           KGRPGWHIECSAMAGTLLGASMDIHGGGFDLRFPHHDNELAQSEAYFENDCWVRYFLHTG
Sbjct: 422 KGRPGWHIECSAMAGTLLGASMDIHGGGFDLRFPHHDNELAQSEAYFENDCWVRYFLHTG 481

Query: 389 HLTIAGCKMSKSLKNFITIKDALKKHSARQLRLAFLMHSWKDTLDYSSNTMESALQYEKF 448
           HLTIAGCKMSKSLKNFITIKDALKKHSARQLRLAFLMHSWKDTLDYSSNTMESALQYEKF
Sbjct: 482 HLTIAGCKMSKSLKNFITIKDALKKHSARQLRLAFLMHSWKDTLDYSSNTMESALQYEKF 541

Query: 449 LNEFFLNVKDILRAPVDITGQFEKWGEEEAELNKNFYDKKTAIHKALCDNVDTRTVMEEM 508
           LNEFFLNVKDILRAPVDITGQFEKWGEEEAELNKNFYDKKTAIHKALCDNVDTRTVMEEM
Sbjct: 542 LNEFFLNVKDILRAPVDITGQFEKWGEEEAELNKNFYDKKTAIHKALCDNVDTRTVMEEM 601

Query: 509 RALVSQCNLYMAARKAVRKRPNQALLENIALYLTHMLKIFGAVEEDSSLGFPVGGPGTSL 568
           RALVSQCNLYMAARKAVRKRPNQALLENIALYLTHMLKIFGAVEEDSSLGFPVGGPGTSL
Sbjct: 602 RALVSQCNLYMAARKAVRKRPNQALLENIALYLTHMLKIFGAVEEDSSLGFPVGGPGTSL 661

Query: 569 SLEATVMPYLQVLSEFREGVRKIAREQKVPEILQLSDALRDNILPELGVRFEDHEGLPTV 628
           SLEATVMPYLQVLSEFREGVRKIAREQKVPEILQLSDALRDNILPELGVRFEDHEGLPTV
Sbjct: 662 SLEATVMPYLQVLSEFREGVRKIAREQKVPEILQLSDALRDNILPELGVRFEDHEGLPTV 721

Query: 629 VKLVDRNTLLKEREEKRRVEEEKRKKKEEAARRKQEQEAAKLAKMKIPPSEMFLSETDKY 688
           VKLVDRNTLLKEREEKRRVEEEKRKKKEEAARRKQEQEAAKLAKMKIPPSEMFLSETDKY
Sbjct: 722 VKLVDRNTLLKEREEKRRVEEEKRKKKEEAARRKQEQEAAKLAKMKIPPSEMFLSETDKY 781

Query: 689 SKFDENGLPTHDMEGKELSKGQAKKLKKLFEAQEKLYKEYLQMAQNGSFQ 738
           SKFDENGLPTHDMEGKELSKGQAKKLKKLFEAQEKLYKEYLQMAQNGSFQ
Sbjct: 782 SKFDENGLPTHDMEGKELSKGQAKKLKKLFEAQEKLYKEYLQMAQNGSFQ 831


>gi|10835051 cysteinyl-tRNA synthetase isoform b [Homo sapiens]
          Length = 748

 Score = 1436 bits (3716), Expect = 0.0
 Identities = 710/710 (100%), Positives = 710/710 (100%)

Query: 29  KEVFIPQDGKKVTWYCCGPTVYDASHMGHARSYISFDILRRVLKDYFKFDVFYCMNITDI 88
           KEVFIPQDGKKVTWYCCGPTVYDASHMGHARSYISFDILRRVLKDYFKFDVFYCMNITDI
Sbjct: 39  KEVFIPQDGKKVTWYCCGPTVYDASHMGHARSYISFDILRRVLKDYFKFDVFYCMNITDI 98

Query: 89  DDKIIKRARQNHLFEQYREKRPEAAQLLEDVQAALKPFSVKLNETTDPDKKQMLERIQHA 148
           DDKIIKRARQNHLFEQYREKRPEAAQLLEDVQAALKPFSVKLNETTDPDKKQMLERIQHA
Sbjct: 99  DDKIIKRARQNHLFEQYREKRPEAAQLLEDVQAALKPFSVKLNETTDPDKKQMLERIQHA 158

Query: 149 VQLATEPLEKAVQSRLTGEEVNSCVEVLLEEAKDLLSDWLDSTLGCDVTDNSIFSKLPKF 208
           VQLATEPLEKAVQSRLTGEEVNSCVEVLLEEAKDLLSDWLDSTLGCDVTDNSIFSKLPKF
Sbjct: 159 VQLATEPLEKAVQSRLTGEEVNSCVEVLLEEAKDLLSDWLDSTLGCDVTDNSIFSKLPKF 218

Query: 209 WEGDFHRDMEALNVLPPDVLTRVSEYVPEIVNFVQKIVDNGYGYVSNGSVYFDTAKFASS 268
           WEGDFHRDMEALNVLPPDVLTRVSEYVPEIVNFVQKIVDNGYGYVSNGSVYFDTAKFASS
Sbjct: 219 WEGDFHRDMEALNVLPPDVLTRVSEYVPEIVNFVQKIVDNGYGYVSNGSVYFDTAKFASS 278

Query: 269 EKHSYGKLVPEAVGDQKALQEGEGDLSISADRLSEKRSPNDFALWKASKPGEPSWPCPWG 328
           EKHSYGKLVPEAVGDQKALQEGEGDLSISADRLSEKRSPNDFALWKASKPGEPSWPCPWG
Sbjct: 279 EKHSYGKLVPEAVGDQKALQEGEGDLSISADRLSEKRSPNDFALWKASKPGEPSWPCPWG 338

Query: 329 KGRPGWHIECSAMAGTLLGASMDIHGGGFDLRFPHHDNELAQSEAYFENDCWVRYFLHTG 388
           KGRPGWHIECSAMAGTLLGASMDIHGGGFDLRFPHHDNELAQSEAYFENDCWVRYFLHTG
Sbjct: 339 KGRPGWHIECSAMAGTLLGASMDIHGGGFDLRFPHHDNELAQSEAYFENDCWVRYFLHTG 398

Query: 389 HLTIAGCKMSKSLKNFITIKDALKKHSARQLRLAFLMHSWKDTLDYSSNTMESALQYEKF 448
           HLTIAGCKMSKSLKNFITIKDALKKHSARQLRLAFLMHSWKDTLDYSSNTMESALQYEKF
Sbjct: 399 HLTIAGCKMSKSLKNFITIKDALKKHSARQLRLAFLMHSWKDTLDYSSNTMESALQYEKF 458

Query: 449 LNEFFLNVKDILRAPVDITGQFEKWGEEEAELNKNFYDKKTAIHKALCDNVDTRTVMEEM 508
           LNEFFLNVKDILRAPVDITGQFEKWGEEEAELNKNFYDKKTAIHKALCDNVDTRTVMEEM
Sbjct: 459 LNEFFLNVKDILRAPVDITGQFEKWGEEEAELNKNFYDKKTAIHKALCDNVDTRTVMEEM 518

Query: 509 RALVSQCNLYMAARKAVRKRPNQALLENIALYLTHMLKIFGAVEEDSSLGFPVGGPGTSL 568
           RALVSQCNLYMAARKAVRKRPNQALLENIALYLTHMLKIFGAVEEDSSLGFPVGGPGTSL
Sbjct: 519 RALVSQCNLYMAARKAVRKRPNQALLENIALYLTHMLKIFGAVEEDSSLGFPVGGPGTSL 578

Query: 569 SLEATVMPYLQVLSEFREGVRKIAREQKVPEILQLSDALRDNILPELGVRFEDHEGLPTV 628
           SLEATVMPYLQVLSEFREGVRKIAREQKVPEILQLSDALRDNILPELGVRFEDHEGLPTV
Sbjct: 579 SLEATVMPYLQVLSEFREGVRKIAREQKVPEILQLSDALRDNILPELGVRFEDHEGLPTV 638

Query: 629 VKLVDRNTLLKEREEKRRVEEEKRKKKEEAARRKQEQEAAKLAKMKIPPSEMFLSETDKY 688
           VKLVDRNTLLKEREEKRRVEEEKRKKKEEAARRKQEQEAAKLAKMKIPPSEMFLSETDKY
Sbjct: 639 VKLVDRNTLLKEREEKRRVEEEKRKKKEEAARRKQEQEAAKLAKMKIPPSEMFLSETDKY 698

Query: 689 SKFDENGLPTHDMEGKELSKGQAKKLKKLFEAQEKLYKEYLQMAQNGSFQ 738
           SKFDENGLPTHDMEGKELSKGQAKKLKKLFEAQEKLYKEYLQMAQNGSFQ
Sbjct: 699 SKFDENGLPTHDMEGKELSKGQAKKLKKLFEAQEKLYKEYLQMAQNGSFQ 748


>gi|21269877 cysteinyl-tRNA synthetase isoform a [Homo sapiens]
          Length = 726

 Score = 1348 bits (3490), Expect = 0.0
 Identities = 666/666 (100%), Positives = 666/666 (100%)

Query: 29  KEVFIPQDGKKVTWYCCGPTVYDASHMGHARSYISFDILRRVLKDYFKFDVFYCMNITDI 88
           KEVFIPQDGKKVTWYCCGPTVYDASHMGHARSYISFDILRRVLKDYFKFDVFYCMNITDI
Sbjct: 39  KEVFIPQDGKKVTWYCCGPTVYDASHMGHARSYISFDILRRVLKDYFKFDVFYCMNITDI 98

Query: 89  DDKIIKRARQNHLFEQYREKRPEAAQLLEDVQAALKPFSVKLNETTDPDKKQMLERIQHA 148
           DDKIIKRARQNHLFEQYREKRPEAAQLLEDVQAALKPFSVKLNETTDPDKKQMLERIQHA
Sbjct: 99  DDKIIKRARQNHLFEQYREKRPEAAQLLEDVQAALKPFSVKLNETTDPDKKQMLERIQHA 158

Query: 149 VQLATEPLEKAVQSRLTGEEVNSCVEVLLEEAKDLLSDWLDSTLGCDVTDNSIFSKLPKF 208
           VQLATEPLEKAVQSRLTGEEVNSCVEVLLEEAKDLLSDWLDSTLGCDVTDNSIFSKLPKF
Sbjct: 159 VQLATEPLEKAVQSRLTGEEVNSCVEVLLEEAKDLLSDWLDSTLGCDVTDNSIFSKLPKF 218

Query: 209 WEGDFHRDMEALNVLPPDVLTRVSEYVPEIVNFVQKIVDNGYGYVSNGSVYFDTAKFASS 268
           WEGDFHRDMEALNVLPPDVLTRVSEYVPEIVNFVQKIVDNGYGYVSNGSVYFDTAKFASS
Sbjct: 219 WEGDFHRDMEALNVLPPDVLTRVSEYVPEIVNFVQKIVDNGYGYVSNGSVYFDTAKFASS 278

Query: 269 EKHSYGKLVPEAVGDQKALQEGEGDLSISADRLSEKRSPNDFALWKASKPGEPSWPCPWG 328
           EKHSYGKLVPEAVGDQKALQEGEGDLSISADRLSEKRSPNDFALWKASKPGEPSWPCPWG
Sbjct: 279 EKHSYGKLVPEAVGDQKALQEGEGDLSISADRLSEKRSPNDFALWKASKPGEPSWPCPWG 338

Query: 329 KGRPGWHIECSAMAGTLLGASMDIHGGGFDLRFPHHDNELAQSEAYFENDCWVRYFLHTG 388
           KGRPGWHIECSAMAGTLLGASMDIHGGGFDLRFPHHDNELAQSEAYFENDCWVRYFLHTG
Sbjct: 339 KGRPGWHIECSAMAGTLLGASMDIHGGGFDLRFPHHDNELAQSEAYFENDCWVRYFLHTG 398

Query: 389 HLTIAGCKMSKSLKNFITIKDALKKHSARQLRLAFLMHSWKDTLDYSSNTMESALQYEKF 448
           HLTIAGCKMSKSLKNFITIKDALKKHSARQLRLAFLMHSWKDTLDYSSNTMESALQYEKF
Sbjct: 399 HLTIAGCKMSKSLKNFITIKDALKKHSARQLRLAFLMHSWKDTLDYSSNTMESALQYEKF 458

Query: 449 LNEFFLNVKDILRAPVDITGQFEKWGEEEAELNKNFYDKKTAIHKALCDNVDTRTVMEEM 508
           LNEFFLNVKDILRAPVDITGQFEKWGEEEAELNKNFYDKKTAIHKALCDNVDTRTVMEEM
Sbjct: 459 LNEFFLNVKDILRAPVDITGQFEKWGEEEAELNKNFYDKKTAIHKALCDNVDTRTVMEEM 518

Query: 509 RALVSQCNLYMAARKAVRKRPNQALLENIALYLTHMLKIFGAVEEDSSLGFPVGGPGTSL 568
           RALVSQCNLYMAARKAVRKRPNQALLENIALYLTHMLKIFGAVEEDSSLGFPVGGPGTSL
Sbjct: 519 RALVSQCNLYMAARKAVRKRPNQALLENIALYLTHMLKIFGAVEEDSSLGFPVGGPGTSL 578

Query: 569 SLEATVMPYLQVLSEFREGVRKIAREQKVPEILQLSDALRDNILPELGVRFEDHEGLPTV 628
           SLEATVMPYLQVLSEFREGVRKIAREQKVPEILQLSDALRDNILPELGVRFEDHEGLPTV
Sbjct: 579 SLEATVMPYLQVLSEFREGVRKIAREQKVPEILQLSDALRDNILPELGVRFEDHEGLPTV 638

Query: 629 VKLVDRNTLLKEREEKRRVEEEKRKKKEEAARRKQEQEAAKLAKMKIPPSEMFLSETDKY 688
           VKLVDRNTLLKEREEKRRVEEEKRKKKEEAARRKQEQEAAKLAKMKIPPSEMFLSETDKY
Sbjct: 639 VKLVDRNTLLKEREEKRRVEEEKRKKKEEAARRKQEQEAAKLAKMKIPPSEMFLSETDKY 698

Query: 689 SKFDEN 694
           SKFDEN
Sbjct: 699 SKFDEN 704


>gi|13375695 cysteinyl-tRNA synthetase 2, mitochondrial [Homo
           sapiens]
          Length = 564

 Score =  241 bits (615), Expect = 2e-63
 Identities = 165/454 (36%), Positives = 229/454 (50%), Gaps = 53/454 (11%)

Query: 203 SKLPKFWEGDFHRDMEALNVLPPDVLTRVSEYVPEIVNFVQKIVDNGYGY-VSNGSVYFD 261
           + L   +E DF +DM AL VLPP V  RV+E +P+I++F++ I+  G  Y  + G+VYFD
Sbjct: 137 ASLASLYEEDFKQDMAALKVLPPTVYLRVTENIPQIISFIEGIIARGNAYSTAKGNVYFD 196

Query: 262 TAKFASSEKHSYGKLV---PEAVGDQKALQEGEGDLSISADRLSEKRSPNDFALWKASKP 318
                 S    YGKLV   P  VG+              AD  S+KR  +DFALWKA+KP
Sbjct: 197 L----KSRGDKYGKLVGVVPGPVGEP-------------AD--SDKRHASDFALWKAAKP 237

Query: 319 GEPSWPCPWGKGRPGWHIECSAMAGTLLGASMDIHGGGFDLRFPHHDNELAQSEAYFEND 378
            E  W  PWG GRPGWHIECSA+A  + G+ +DIH GG DL FPHH+NE+AQ E + + +
Sbjct: 238 QEVFWASPWGPGRPGWHIECSAIASMVFGSQLDIHSGGIDLAFPHHENEIAQCEVFHQCE 297

Query: 379 CWVRYFLHTGHLTIAGC--KMSKSLKNFITIKDALKKHSARQLRLAFLMHSWKDTLDYSS 436
            W  YFLH+GHL   G   KMSKSLKN+ITIKD LK  S    R   L  S++  +DYS 
Sbjct: 298 QWGNYFLHSGHLHAKGKEEKMSKSLKNYITIKDFLKTFSPDVFRFFCLRSSYRSAIDYSD 357

Query: 437 NTMESALQYEKFLNEFFLNVKDILRAPVDITGQFEKWGEEEAELNKNFYDKKTAIHKALC 496
           + M  A Q    L  F  + +  ++      GQ       EA L +     K A+  AL 
Sbjct: 358 SAMLQAQQLLLGLGSFLEDARAYMK------GQLACGSVREAMLWERLSSTKRAVKAALA 411

Query: 497 DNVDTRTVMEEMRALVSQCNLYMAARKAVRKRP-NQALLENIALYLTHMLKIFGAVEEDS 555
           D+ DT  V++ +  L    N  + A     + P + A+   I  Y     +  G    + 
Sbjct: 412 DDFDTPRVVDAILGLAHHGNGQLRASLKEPEGPRSPAVFGAIISYFEQFFETVGISLANQ 471

Query: 556 SLGFPVGGPGTSLSLEATVMPYLQVLSEFREGVRKI----------AREQKVPE---ILQ 602
                V G G+    EAT+   +  L  FR+ VR+           AR Q++ E   +L+
Sbjct: 472 QY---VSGDGS----EATLHGVVDELVRFRQKVRQFALAMPEATGDARRQQLLERQPLLE 524

Query: 603 LSDALRDNILPELGVRFEDHEGLPTVVKLVDRNT 636
             D LR  +    G+  +D     +  +L+D+ T
Sbjct: 525 ACDTLRRGLTAH-GINIKDRSSTTSTWELLDQRT 557



 Score = 84.0 bits (206), Expect = 5e-16
 Identities = 37/73 (50%), Positives = 49/73 (67%)

Query: 29  KEVFIPQDGKKVTWYCCGPTVYDASHMGHARSYISFDILRRVLKDYFKFDVFYCMNITDI 88
           KE  I    +  +WY CGPTVYD +H+GHA SY+ FDI+RR+L   F   +   M ITD+
Sbjct: 62  KEPLIVAHAEAASWYSCGPTVYDHAHLGHACSYVRFDIIRRILTKVFGCSIVMVMGITDV 121

Query: 89  DDKIIKRARQNHL 101
           DDKIIKRA + ++
Sbjct: 122 DDKIIKRANEMNI 134


>gi|11693132 UPF2 regulator of nonsense transcripts homolog [Homo
           sapiens]
          Length = 1272

 Score = 45.1 bits (105), Expect = 2e-04
 Identities = 21/36 (58%), Positives = 29/36 (80%)

Query: 639 KEREEKRRVEEEKRKKKEEAARRKQEQEAAKLAKMK 674
           KE EEK++ +EE+RKK+EE A+R+QE+EAA   K K
Sbjct: 89  KEEEEKKKHQEEERKKQEEQAKRQQEEEAAAQMKEK 124



 Score = 38.1 bits (87), Expect = 0.030
 Identities = 31/136 (22%), Positives = 61/136 (44%), Gaps = 8/136 (5%)

Query: 594 EQKVPEILQLSDALRDNILPELGVR--FEDHEGLPTVVKLVDRNTLLKEREEKRRVEEEK 651
           E+K P  ++  D+L +N   +   R      E     +KL  +  + K  E+K++  E+ 
Sbjct: 4   ERKKPASMEEKDSLPNNKEKDCSERRTVSSKERPKDDIKLTAKKEVSKAPEDKKKRLEDD 63

Query: 652 RKKKEEAARRKQEQEAAKLAKMKIPPSEMFLSETDKYSKFDENGLPTHDMEGKELSKGQA 711
           ++KKE+  R+K+++E  K  +      E    E ++  K  E      + + K   + +A
Sbjct: 64  KRKKEDKERKKKDEEKVKAEE------ESKKKEEEEKKKHQEEERKKQEEQAKRQQEEEA 117

Query: 712 KKLKKLFEAQEKLYKE 727
               K  E   +L++E
Sbjct: 118 AAQMKEKEESIQLHQE 133


>gi|18375676 UPF2 regulator of nonsense transcripts homolog [Homo
           sapiens]
          Length = 1272

 Score = 45.1 bits (105), Expect = 2e-04
 Identities = 21/36 (58%), Positives = 29/36 (80%)

Query: 639 KEREEKRRVEEEKRKKKEEAARRKQEQEAAKLAKMK 674
           KE EEK++ +EE+RKK+EE A+R+QE+EAA   K K
Sbjct: 89  KEEEEKKKHQEEERKKQEEQAKRQQEEEAAAQMKEK 124



 Score = 38.1 bits (87), Expect = 0.030
 Identities = 31/136 (22%), Positives = 61/136 (44%), Gaps = 8/136 (5%)

Query: 594 EQKVPEILQLSDALRDNILPELGVR--FEDHEGLPTVVKLVDRNTLLKEREEKRRVEEEK 651
           E+K P  ++  D+L +N   +   R      E     +KL  +  + K  E+K++  E+ 
Sbjct: 4   ERKKPASMEEKDSLPNNKEKDCSERRTVSSKERPKDDIKLTAKKEVSKAPEDKKKRLEDD 63

Query: 652 RKKKEEAARRKQEQEAAKLAKMKIPPSEMFLSETDKYSKFDENGLPTHDMEGKELSKGQA 711
           ++KKE+  R+K+++E  K  +      E    E ++  K  E      + + K   + +A
Sbjct: 64  KRKKEDKERKKKDEEKVKAEE------ESKKKEEEEKKKHQEEERKKQEEQAKRQQEEEA 117

Query: 712 KKLKKLFEAQEKLYKE 727
               K  E   +L++E
Sbjct: 118 AAQMKEKEESIQLHQE 133


>gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-like
           [Homo sapiens]
          Length = 899

 Score = 42.7 bits (99), Expect = 0.001
 Identities = 31/123 (25%), Positives = 62/123 (50%), Gaps = 9/123 (7%)

Query: 612 LPELGVRFEDHEGLPTVVKLVDRNTLLKEREEKRRVEEEKRKKKEEAARRKQEQEAAKLA 671
           LPE   +  +HE +    K+ ++   ++++EEK R +EEK + +EE  R ++E+   +  
Sbjct: 770 LPEQKEKLWEHEKMQEQEKIWEQEEKMRDQEEKMRGQEEKMRGQEEKMRGQEEKMWGQEE 829

Query: 672 KMKIPPSEMFLSETDKYSKFDE-----NGLPTHDMEGKELSKGQAKKLK----KLFEAQE 722
           KM     +M+  E   + + ++      G      E +E  +GQ +K++    K+   +E
Sbjct: 830 KMWGQEEKMWGQEEKMWGQEEKMEEKMQGQEEKMREQEEKMRGQEEKMREQEEKMRGQEE 889

Query: 723 KLY 725
           K+Y
Sbjct: 890 KIY 892



 Score = 38.1 bits (87), Expect = 0.030
 Identities = 28/116 (24%), Positives = 60/116 (51%), Gaps = 7/116 (6%)

Query: 620 EDHEGLPTVVKLVDRNTLLKEREEKRRVEEEKRKKKEEAARRKQEQEAAKLAKMKIPPSE 679
           +  E +    ++ +R   ++E EE  R +EEK +K+EE      EQE  +  + ++P  +
Sbjct: 441 DQEEKMQEEERIREREKKMREEEETMREQEEKMQKQEE---NMWEQEEKEWQQQRLPEQK 497

Query: 680 MFLSETDKYSKFDENGLPTHD-MEGKELSKGQAKKL---KKLFEAQEKLYKEYLQM 731
             L E +K  + +E      + +  +E   GQ KK+   +K+ E +++++++  +M
Sbjct: 498 EKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKM 553



 Score = 36.6 bits (83), Expect = 0.086
 Identities = 30/108 (27%), Positives = 58/108 (53%), Gaps = 9/108 (8%)

Query: 632 VDRNTLLKE---REEKRRVEEEKRKKKEEAARRKQEQEAAKLAKMKIPPSEMF-----LS 683
           V  NTL +E   +EE+ R +E+K +K+EE   R++E+   +  KM+    +M+     L 
Sbjct: 265 VQTNTLQEEMWRQEEELREQEKKIRKQEEKMWRQEERLREQEGKMREQEEKMWRQEKRLR 324

Query: 684 ETDKYSKFDENGLPTHDMEGKELSKGQAKKLKKLFEAQEKLYKEYLQM 731
           E +K  +  E  L     E +E  +   ++ +K++E +EK+ ++  +M
Sbjct: 325 EQEKELREQEKEL-REQKELREQEEQMQEQEEKMWEQEEKMREQEEKM 371



 Score = 36.6 bits (83), Expect = 0.086
 Identities = 29/119 (24%), Positives = 55/119 (46%), Gaps = 5/119 (4%)

Query: 620 EDHEGLPTVVKLVDRNTLLKEREEKRRVEEE-----KRKKKEEAARRKQEQEAAKLAKMK 674
           E  E L    K+ ++   + E+EEK R +EE     K+  ++E  R +++Q   +  KM+
Sbjct: 495 EQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMR 554

Query: 675 IPPSEMFLSETDKYSKFDENGLPTHDMEGKELSKGQAKKLKKLFEAQEKLYKEYLQMAQ 733
               +M+  E     K  E    T D E K   + + ++ +K    +E++ +E  +  Q
Sbjct: 555 DQEQKMWDQEERMEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQEEKMQ 613



 Score = 36.2 bits (82), Expect = 0.11
 Identities = 25/113 (22%), Positives = 59/113 (52%), Gaps = 6/113 (5%)

Query: 619 FEDHEGLPTVVKLVDRNTLLKEREEKRRVEEEKRKKKEEAARRKQEQEAAKLAKMKIPPS 678
           ++  E +    ++ +R   ++E EE  R +EEK +++EE  + ++E+   +  KM+    
Sbjct: 579 WDQEEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMQEQEEKMWEQEEKMQEQEE 638

Query: 679 EMFLSETDKYSK----FDENGLPTHDMEGKELSKGQAKKLKKLFEAQEKLYKE 727
           +M+  E   + +    +++  LP    +  E  K Q +  +K+ E +EK++++
Sbjct: 639 KMWEQEEKMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQ--EKMQEQEEKIWEQ 689



 Score = 36.2 bits (82), Expect = 0.11
 Identities = 22/116 (18%), Positives = 57/116 (49%), Gaps = 8/116 (6%)

Query: 612 LPELGVRFEDHEGLPTVVKLVDRNTLLKEREEKRRVEEEKRKKKEEAARRKQEQEAAKLA 671
           LPE   +  +HE +    K+ ++   + E+E+  +  +E+ KK  +  + ++E+   +  
Sbjct: 660 LPEQKEKLWEHEKMQEQEKMQEQEEKIWEQEKMEKKTQEQEKKTWDQEKMREEESMRERE 719

Query: 672 KMKIPPSEMFLSETDKYSKFDENGLPTHDMEGKELSKGQAKKLKKLFEAQEKLYKE 727
           K      EM   + +K  + +E        + +E  +   ++ +K++E +EK++++
Sbjct: 720 KKMREEEEMMREQEEKMQEQEE--------KMQEQEEEMWEQEEKMWEQEEKMWEQ 767



 Score = 35.8 bits (81), Expect = 0.15
 Identities = 29/121 (23%), Positives = 62/121 (51%), Gaps = 6/121 (4%)

Query: 608 RDNILPELGVRFEDHEGLPTVVKLVDRNTLLKEREEKRRVEEEKRKKKEEAARR----KQ 663
           +D  L E   R  + E +   V+ +     ++E+E+K R +EEK +++E    R    ++
Sbjct: 402 QDERLREKEERMREQEKMWEQVEKMREEKKMQEQEKKTRDQEEKMQEEERIREREKKMRE 461

Query: 664 EQEAAKLAKMKIPPSEMFLSETDKYSKFDENGLPTHDMEGKELSKGQAKKLKKLFEAQEK 723
           E+E  +  + K+   E  + E ++  ++ +  LP    +  E  K Q ++ +K++E +EK
Sbjct: 462 EEETMREQEEKMQKQEENMWEQEE-KEWQQQRLPEQKEKLWEQEKMQEQE-EKIWEQEEK 519

Query: 724 L 724
           +
Sbjct: 520 I 520



 Score = 33.9 bits (76), Expect = 0.56
 Identities = 35/156 (22%), Positives = 73/156 (46%), Gaps = 23/156 (14%)

Query: 583 EFREGVRKIAREQKVPEILQLSDALRDNILPELGVRFEDHEGLPTVVKLVDRNTLLKERE 642
           + RE  R   RE+K+ E         + ++ E   + ++ E      K+ ++   + E+E
Sbjct: 584 KMREEERMREREKKMRE--------EEEMMREQEEKMQEQEE-----KMQEQEEKMWEQE 630

Query: 643 EKRRVEEEKRKKKEEAARRKQEQEAAKLAKMKIPPSEMFLSETDKYSKFDENGLPTHDME 702
           EK + +EEK  ++EE   +  EQE     + ++P  +  L E +K  + ++       M+
Sbjct: 631 EKMQEQEEKMWEQEE---KMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQEK-------MQ 680

Query: 703 GKELSKGQAKKLKKLFEAQEKLYKEYLQMAQNGSFQ 738
            +E    + +K++K  + QEK   +  +M +  S +
Sbjct: 681 EQEEKIWEQEKMEKKTQEQEKKTWDQEKMREEESMR 716



 Score = 32.7 bits (73), Expect = 1.2
 Identities = 23/107 (21%), Positives = 49/107 (45%), Gaps = 12/107 (11%)

Query: 630 KLVDRNTLLKEREEKRRVEEEKRKKKEEAARRKQEQEAAKLAKMKIPPSEMFLSETDKY- 688
           +L ++   ++E+E+K R +EE+  +++E  R K+E         ++   E    + +K  
Sbjct: 377 RLWEQEKQMREQEQKMRDQEERMWEQDERLREKEE---------RMREQEKMWEQVEKMR 427

Query: 689 --SKFDENGLPTHDMEGKELSKGQAKKLKKLFEAQEKLYKEYLQMAQ 733
              K  E    T D E K   + + ++ +K    +E+  +E  +  Q
Sbjct: 428 EEKKMQEQEKKTRDQEEKMQEEERIREREKKMREEEETMREQEEKMQ 474



 Score = 31.6 bits (70), Expect = 2.8
 Identities = 24/122 (19%), Positives = 59/122 (48%), Gaps = 8/122 (6%)

Query: 618 RFEDHEGLPTVVKLVDRNTLLKEREEKRRVEEEKRK--------KKEEAARRKQEQEAAK 669
           +  D E +    K + R   ++E+E++   +EEK +        ++E   ++ QEQE   
Sbjct: 519 KIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMEKKTQEQEKKT 578

Query: 670 LAKMKIPPSEMFLSETDKYSKFDENGLPTHDMEGKELSKGQAKKLKKLFEAQEKLYKEYL 729
             + +    E  + E +K  + +E  +   + + +E  +   ++ +K++E +EK+ ++  
Sbjct: 579 WDQEEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMQEQEEKMWEQEEKMQEQEE 638

Query: 730 QM 731
           +M
Sbjct: 639 KM 640



 Score = 31.2 bits (69), Expect = 3.6
 Identities = 26/118 (22%), Positives = 58/118 (49%), Gaps = 10/118 (8%)

Query: 620 EDHEGLPTVVKLVDRNTLLKEREEKRRVEEEKRKKKEEAARRKQE-----QEAAKLAKMK 674
           E  + L    +L ++   ++E+EEK   +EEK +++EE   R++E     ++  +  + K
Sbjct: 332 EQEKELREQKELREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQK 391

Query: 675 IPPSEMFLSETDKYSKFDENGLPTHDMEGKELSKGQAKKL-----KKLFEAQEKLYKE 727
           +   E  + E D+  +  E  +   +   +++ K + +K      KK  + +EK+ +E
Sbjct: 392 MRDQEERMWEQDERLREKEERMREQEKMWEQVEKMREEKKMQEQEKKTRDQEEKMQEE 449



 Score = 30.8 bits (68), Expect = 4.7
 Identities = 25/117 (21%), Positives = 62/117 (52%), Gaps = 3/117 (2%)

Query: 611 ILPELGVRFEDHEGLPTVVKLVDRNTLLKEREEKRRVEEEKRKKKEEAARRKQEQEAAKL 670
           +LP++       E      +L ++   ++++EEK   +EE R +++E   R+QE++  + 
Sbjct: 261 LLPQVQTNTLQEEMWRQEEELREQEKKIRKQEEKMWRQEE-RLREQEGKMREQEEKMWRQ 319

Query: 671 AKMKIPPSEMFLSETDKYSKFDENGLPTHDMEGKELSKGQAKKLKKLFEAQEKLYKE 727
            K ++   E  L E +K  + ++  L   + + +E  +   ++ +K+ E +EK++++
Sbjct: 320 EK-RLREQEKELREQEKELR-EQKELREQEEQMQEQEEKMWEQEEKMREQEEKMWRQ 374


>gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-like
           [Homo sapiens]
          Length = 828

 Score = 42.4 bits (98), Expect = 0.002
 Identities = 24/115 (20%), Positives = 61/115 (53%)

Query: 619 FEDHEGLPTVVKLVDRNTLLKEREEKRRVEEEKRKKKEEAARRKQEQEAAKLAKMKIPPS 678
           ++  E +    ++ +R   ++E EE  R +EEK +++EE  R ++E+   +  KM+    
Sbjct: 550 WDQEEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEE 609

Query: 679 EMFLSETDKYSKFDENGLPTHDMEGKELSKGQAKKLKKLFEAQEKLYKEYLQMAQ 733
           +M+  E   + + +E+ +   +    E  +   ++ +K++E +EK+ ++  +M +
Sbjct: 610 KMWEQEEKMWEQEEEDKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMRE 664



 Score = 40.4 bits (93), Expect = 0.006
 Identities = 31/132 (23%), Positives = 68/132 (51%), Gaps = 8/132 (6%)

Query: 608 RDNILPELGVRFEDHEGLPTVVKLVDRNTLLKEREEKRRVEEEKRKKKEEAARRKQ---- 663
           +D  L E   R  + E +    + +     ++ERE+K R EEE  +++EE  ++++    
Sbjct: 364 QDERLREKEERMREQEKMWEQEEKMQEEERIREREKKMREEEETMREQEEKMQKQEENMW 423

Query: 664 EQEAAKLAKMKIPPSEMFLSETDKYSKFDENGLPTHD-MEGKELSKGQAKKL---KKLFE 719
           EQE  +  + ++P  +  L E +K  + +E      + +  +E   GQ KK+   +K+ E
Sbjct: 424 EQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMRE 483

Query: 720 AQEKLYKEYLQM 731
            +++++++  +M
Sbjct: 484 QEDQMWEQEEKM 495



 Score = 37.0 bits (84), Expect = 0.066
 Identities = 23/89 (25%), Positives = 49/89 (55%), Gaps = 2/89 (2%)

Query: 639 KEREEKRRVEEEKRKKKEEAARRKQEQEAAKLAKMKIPPSEMFLSETDKYSKFDENGLPT 698
           K REEK+  E+EK+   +E   R++E+   +  KM+    EM   + +K  + +E     
Sbjct: 535 KMREEKKTQEQEKKTWDQEEKMREEERMREREKKMR-EEEEMMREQEEKMQEQEEKMREQ 593

Query: 699 HDMEGKELSKGQAKKLKKLFEAQEKLYKE 727
            +   ++  K Q ++ +K++E +EK++++
Sbjct: 594 EEKMWEQEEKMQEQE-EKMWEQEEKMWEQ 621



 Score = 37.0 bits (84), Expect = 0.066
 Identities = 22/99 (22%), Positives = 51/99 (51%)

Query: 630 KLVDRNTLLKEREEKRRVEEEKRKKKEEAARRKQEQEAAKLAKMKIPPSEMFLSETDKYS 689
           K+ ++   ++E+EEK R +EEK + +EE  R ++E+   +  KM+    +M   E   + 
Sbjct: 647 KMWEQEEKMREQEEKMREQEEKMQGQEEKMREQEEKMQGQEEKMREQEEKMRGQEEKMWG 706

Query: 690 KFDENGLPTHDMEGKELSKGQAKKLKKLFEAQEKLYKEY 728
           + ++       M G+E  + + ++++   E  ++   E+
Sbjct: 707 QEEKMWGQEEKMWGQEEMREKEERIRDQKEKMQERLPEH 745



 Score = 35.8 bits (81), Expect = 0.15
 Identities = 34/142 (23%), Positives = 71/142 (50%), Gaps = 13/142 (9%)

Query: 593 REQKVPEILQLSDALRDNILPELGVRFEDHEGLPTVVKLVDRNTLLKE---REEKRRVEE 649
           +  ++ E L+L+++ +  I   +       E    ++  V  NTL +E   +EE+ R +E
Sbjct: 188 KNAELQEKLRLAESEKSEIQLNVKELKRKLERAKFLLPQVQTNTLQEEMWRQEEELREQE 247

Query: 650 EKRKKKEEAARRKQEQEAAKLAKMKIPPSEMFLSETDKYSKFDENGLPTHDMEGKELSKG 709
           +K +K+EE   R++E+   +  KM+         E ++  +  E  L   + E +E  K 
Sbjct: 248 KKIRKQEEKMWRQEERLREQEGKMR---------EQEEKMRRQEKRLREQEKELREQEK- 297

Query: 710 QAKKLKKLFEAQEKLYKEYLQM 731
           + ++ KKL E +E++ ++  +M
Sbjct: 298 ELREQKKLREQEEQMQEQEEKM 319



 Score = 34.7 bits (78), Expect = 0.33
 Identities = 22/95 (23%), Positives = 53/95 (55%), Gaps = 6/95 (6%)

Query: 638 LKEREEKRRVEEEKRKKKEEAARR-----KQEQEAAKLAKMKIPPSEMFLSETDKYSKFD 692
           L+E+E+K R +EEK  ++EE  R      ++++E  +  + ++   E  L E +K  + +
Sbjct: 243 LREQEKKIRKQEEKMWRQEERLREQEGKMREQEEKMRRQEKRLREQEKELREQEKELR-E 301

Query: 693 ENGLPTHDMEGKELSKGQAKKLKKLFEAQEKLYKE 727
           +  L   + + +E  +   ++ +K+ E +EK++++
Sbjct: 302 QKKLREQEEQMQEQEEKMWEQEEKMREQEEKMWRQ 336



 Score = 34.7 bits (78), Expect = 0.33
 Identities = 25/100 (25%), Positives = 55/100 (55%), Gaps = 10/100 (10%)

Query: 630 KLVDRNTLLKEREEKRRVEEEKRKKKEEAARRKQEQEAAKLAKMKIPPSEMFLSETDKYS 689
           K+ ++  ++ E+EEK + +EEK  ++EE  R ++E+   +  KM+    E  + E ++  
Sbjct: 626 KMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQ--GQEEKMREQEEKM 683

Query: 690 KFDENGLPTHDMEGKELSKGQAKKL----KKLFEAQEKLY 725
           +  E  +     E +E  +GQ +K+    +K++  +EK++
Sbjct: 684 QGQEEKM----REQEEKMRGQEEKMWGQEEKMWGQEEKMW 719



 Score = 34.7 bits (78), Expect = 0.33
 Identities = 21/98 (21%), Positives = 51/98 (52%)

Query: 630 KLVDRNTLLKEREEKRRVEEEKRKKKEEAARRKQEQEAAKLAKMKIPPSEMFLSETDKYS 689
           K+ ++   ++E+EEK + +EEK +++EE  + ++E+   +  KM+    +M+  E   + 
Sbjct: 654 KMREQEEKMREQEEKMQGQEEKMREQEEKMQGQEEKMREQEEKMRGQEEKMWGQEEKMWG 713

Query: 690 KFDENGLPTHDMEGKELSKGQAKKLKKLFEAQEKLYKE 727
           + ++        E +E  + Q +K+++     E+   E
Sbjct: 714 QEEKMWGQEEMREKEERIRDQKEKMQERLPEHEERCSE 751



 Score = 34.3 bits (77), Expect = 0.43
 Identities = 33/151 (21%), Positives = 72/151 (47%), Gaps = 13/151 (8%)

Query: 583 EFREGVRKIAREQKVPEILQLSDALRDNILPELGVRFEDHEGLPTVVKLVDRNTLLKERE 642
           + RE  R   RE+K+ E  ++     + +  +     E  E      K+ ++   ++E+E
Sbjct: 555 KMREEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEE------KMWEQEEKMQEQE 608

Query: 643 EKRRVEEEKRKKKEEAARRKQEQEAAKLAKMKIPPSEMFLSETDKYSKFDENGLPTHDME 702
           EK   +EEK  ++EE  + ++++E     + K+   E  + E ++  +  E  +     E
Sbjct: 609 EKMWEQEEKMWEQEEEDKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKM----RE 664

Query: 703 GKELSKGQAKKLKKLFEAQEKLYKEYLQMAQ 733
            +E  +GQ +K++   E +EK+  +  +M +
Sbjct: 665 QEEKMQGQEEKMR---EQEEKMQGQEEKMRE 692



 Score = 33.9 bits (76), Expect = 0.56
 Identities = 24/105 (22%), Positives = 58/105 (55%), Gaps = 4/105 (3%)

Query: 630 KLVDRNTLLKEREEKRRVEEEKRKKKEEAAR---RKQEQEAAKLAKMKIPPSEMFLSETD 686
           ++ +++  L+E+EE+ R E++K  ++EE  R   + QEQE     + +    E  + E +
Sbjct: 508 RMWEQDERLREKEERMR-EQKKMWQQEEKMREEKKTQEQEKKTWDQEEKMREEERMRERE 566

Query: 687 KYSKFDENGLPTHDMEGKELSKGQAKKLKKLFEAQEKLYKEYLQM 731
           K  + +E  +   + + +E  +   ++ +K++E +EK+ ++  +M
Sbjct: 567 KKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKM 611



 Score = 33.1 bits (74), Expect = 0.95
 Identities = 25/108 (23%), Positives = 55/108 (50%), Gaps = 10/108 (9%)

Query: 620 EDHEGLPTVVKLVDRNTLLKEREEKRRVEEEKRKKKEEAARRKQEQEAAKLAKMKIPPSE 679
           E  + L    KL ++   ++E+EEK   +EEK +++EE   R++E         ++   E
Sbjct: 294 EQEKELREQKKLREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEE---------RLWEQE 344

Query: 680 MFLSETDKYSKFDENGLPTHDMEGKELSKGQAKKLKKLFEAQEKLYKE 727
             + E ++  +  E  +   D   +E  + + ++ +K++E +EK+ +E
Sbjct: 345 KQMREQEQKMRDQEERMWEQDERLRE-KEERMREQEKMWEQEEKMQEE 391



 Score = 33.1 bits (74), Expect = 0.95
 Identities = 27/99 (27%), Positives = 54/99 (54%), Gaps = 8/99 (8%)

Query: 630 KLVDRNTLLKEREEKRRVEEEKRKKKEEAARRKQEQEAAKLAKMKIPPSEMFLSE-TDKY 688
           ++ +++  L+E+EE+ R E+EK  ++EE   + QE+E  +  + K+   E  + E  +K 
Sbjct: 360 RMWEQDERLREKEERMR-EQEKMWEQEE---KMQEEERIREREKKMREEEETMREQEEKM 415

Query: 689 SKFDENGLPTHDMEGKELSKGQAKKLKKLFEAQEKLYKE 727
            K +EN     + E KE  + +  + K+    QEK+ ++
Sbjct: 416 QKQEEN---MWEQEEKEWQQQRLPEQKEKLWEQEKMQEQ 451



 Score = 30.8 bits (68), Expect = 4.7
 Identities = 25/106 (23%), Positives = 50/106 (47%), Gaps = 3/106 (2%)

Query: 630 KLVDRNTLLKEREEKRRVEEEKRKKKEEAARRKQEQEAAKLAKMKIPPSEMFLSETD--K 687
           K+ ++   + E+EEK R +E+K   +EE    + E+   K  +M+    +M+  E    +
Sbjct: 480 KMREQEDQMWEQEEKMRDQEQKMWDQEERMWEQDERLREKEERMR-EQKKMWQQEEKMRE 538

Query: 688 YSKFDENGLPTHDMEGKELSKGQAKKLKKLFEAQEKLYKEYLQMAQ 733
             K  E    T D E K   + + ++ +K    +E++ +E  +  Q
Sbjct: 539 EKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQEEKMQ 584


>gi|15149465 caldesmon 1 isoform 5 [Homo sapiens]
          Length = 532

 Score = 41.6 bits (96), Expect = 0.003
 Identities = 32/90 (35%), Positives = 50/90 (55%), Gaps = 5/90 (5%)

Query: 637 LLKEREEKRRV--EEEKRKKKEEAARRKQEQEAAKLAKMKIPPSEMFLSETDKYSKFDEN 694
           L K+REE+R+V  EEE+R+K+EEA R+ +E+E  +  K +I       +E  K  K  E+
Sbjct: 307 LKKKREERRKVLEEEEQRRKQEEADRKLREEEEKRRLKEEIERRRAEAAE--KRQKMPED 364

Query: 695 GLPTHDMEGKELS-KGQAKKLKKLFEAQEK 723
           GL       K  + KG + K+++  E   K
Sbjct: 365 GLSDDKKPFKCFTPKGSSLKIEERAEFLNK 394



 Score = 30.4 bits (67), Expect = 6.2
 Identities = 27/85 (31%), Positives = 40/85 (47%), Gaps = 5/85 (5%)

Query: 639 KEREEKRRVEEEKRKKKEEAARRKQEQEAAKLAKMKIPPSEMFLSETDKYSKFDENGLPT 698
           KE E   +VE  KR   EE  RR+ E E+ +  K+K    E  L   +   K +E     
Sbjct: 261 KEAEGAPQVEAGKRL--EELRRRRGETESEEFEKLKQKQQEAALELEELKKKREER---R 315

Query: 699 HDMEGKELSKGQAKKLKKLFEAQEK 723
             +E +E  + Q +  +KL E +EK
Sbjct: 316 KVLEEEEQRRKQEEADRKLREEEEK 340


>gi|15149463 caldesmon 1 isoform 4 [Homo sapiens]
          Length = 558

 Score = 41.6 bits (96), Expect = 0.003
 Identities = 32/90 (35%), Positives = 50/90 (55%), Gaps = 5/90 (5%)

Query: 637 LLKEREEKRRV--EEEKRKKKEEAARRKQEQEAAKLAKMKIPPSEMFLSETDKYSKFDEN 694
           L K+REE+R+V  EEE+R+K+EEA R+ +E+E  +  K +I       +E  K  K  E+
Sbjct: 333 LKKKREERRKVLEEEEQRRKQEEADRKLREEEEKRRLKEEIERRRAEAAE--KRQKMPED 390

Query: 695 GLPTHDMEGKELS-KGQAKKLKKLFEAQEK 723
           GL       K  + KG + K+++  E   K
Sbjct: 391 GLSDDKKPFKCFTPKGSSLKIEERAEFLNK 420



 Score = 30.4 bits (67), Expect = 6.2
 Identities = 27/85 (31%), Positives = 40/85 (47%), Gaps = 5/85 (5%)

Query: 639 KEREEKRRVEEEKRKKKEEAARRKQEQEAAKLAKMKIPPSEMFLSETDKYSKFDENGLPT 698
           KE E   +VE  KR   EE  RR+ E E+ +  K+K    E  L   +   K +E     
Sbjct: 287 KEAEGAPQVEAGKRL--EELRRRRGETESEEFEKLKQKQQEAALELEELKKKREER---R 341

Query: 699 HDMEGKELSKGQAKKLKKLFEAQEK 723
             +E +E  + Q +  +KL E +EK
Sbjct: 342 KVLEEEEQRRKQEEADRKLREEEEK 366


>gi|15149467 caldesmon 1 isoform 3 [Homo sapiens]
          Length = 564

 Score = 41.6 bits (96), Expect = 0.003
 Identities = 32/90 (35%), Positives = 50/90 (55%), Gaps = 5/90 (5%)

Query: 637 LLKEREEKRRV--EEEKRKKKEEAARRKQEQEAAKLAKMKIPPSEMFLSETDKYSKFDEN 694
           L K+REE+R+V  EEE+R+K+EEA R+ +E+E  +  K +I       +E  K  K  E+
Sbjct: 339 LKKKREERRKVLEEEEQRRKQEEADRKLREEEEKRRLKEEIERRRAEAAE--KRQKMPED 396

Query: 695 GLPTHDMEGKELS-KGQAKKLKKLFEAQEK 723
           GL       K  + KG + K+++  E   K
Sbjct: 397 GLSDDKKPFKCFTPKGSSLKIEERAEFLNK 426



 Score = 30.4 bits (67), Expect = 6.2
 Identities = 27/85 (31%), Positives = 40/85 (47%), Gaps = 5/85 (5%)

Query: 639 KEREEKRRVEEEKRKKKEEAARRKQEQEAAKLAKMKIPPSEMFLSETDKYSKFDENGLPT 698
           KE E   +VE  KR   EE  RR+ E E+ +  K+K    E  L   +   K +E     
Sbjct: 293 KEAEGAPQVEAGKRL--EELRRRRGETESEEFEKLKQKQQEAALELEELKKKREER---R 347

Query: 699 HDMEGKELSKGQAKKLKKLFEAQEK 723
             +E +E  + Q +  +KL E +EK
Sbjct: 348 KVLEEEEQRRKQEEADRKLREEEEK 372


>gi|4826657 caldesmon 1 isoform 2 [Homo sapiens]
          Length = 538

 Score = 41.6 bits (96), Expect = 0.003
 Identities = 32/90 (35%), Positives = 50/90 (55%), Gaps = 5/90 (5%)

Query: 637 LLKEREEKRRV--EEEKRKKKEEAARRKQEQEAAKLAKMKIPPSEMFLSETDKYSKFDEN 694
           L K+REE+R+V  EEE+R+K+EEA R+ +E+E  +  K +I       +E  K  K  E+
Sbjct: 313 LKKKREERRKVLEEEEQRRKQEEADRKLREEEEKRRLKEEIERRRAEAAE--KRQKMPED 370

Query: 695 GLPTHDMEGKELS-KGQAKKLKKLFEAQEK 723
           GL       K  + KG + K+++  E   K
Sbjct: 371 GLSDDKKPFKCFTPKGSSLKIEERAEFLNK 400



 Score = 30.4 bits (67), Expect = 6.2
 Identities = 27/85 (31%), Positives = 40/85 (47%), Gaps = 5/85 (5%)

Query: 639 KEREEKRRVEEEKRKKKEEAARRKQEQEAAKLAKMKIPPSEMFLSETDKYSKFDENGLPT 698
           KE E   +VE  KR   EE  RR+ E E+ +  K+K    E  L   +   K +E     
Sbjct: 267 KEAEGAPQVEAGKRL--EELRRRRGETESEEFEKLKQKQQEAALELEELKKKREER---R 321

Query: 699 HDMEGKELSKGQAKKLKKLFEAQEK 723
             +E +E  + Q +  +KL E +EK
Sbjct: 322 KVLEEEEQRRKQEEADRKLREEEEK 346


>gi|44680105 caldesmon 1 isoform 1 [Homo sapiens]
          Length = 793

 Score = 41.6 bits (96), Expect = 0.003
 Identities = 32/90 (35%), Positives = 50/90 (55%), Gaps = 5/90 (5%)

Query: 637 LLKEREEKRRV--EEEKRKKKEEAARRKQEQEAAKLAKMKIPPSEMFLSETDKYSKFDEN 694
           L K+REE+R+V  EEE+R+K+EEA R+ +E+E  +  K +I       +E  K  K  E+
Sbjct: 568 LKKKREERRKVLEEEEQRRKQEEADRKLREEEEKRRLKEEIERRRAEAAE--KRQKMPED 625

Query: 695 GLPTHDMEGKELS-KGQAKKLKKLFEAQEK 723
           GL       K  + KG + K+++  E   K
Sbjct: 626 GLSDDKKPFKCFTPKGSSLKIEERAEFLNK 655



 Score = 35.8 bits (81), Expect = 0.15
 Identities = 32/140 (22%), Positives = 60/140 (42%), Gaps = 5/140 (3%)

Query: 593 REQKVPEILQLSDALRDNILPELGVRFEDHEG-LPTVVKLVDRNTLLKEREEKRRVEEEK 651
           +E+   E  +L    R+ I  E   +  D    +    K   +    +E EE+ R+ EE+
Sbjct: 262 KERAEAERARLEAEERERIKAEQDKKIADERARIEAEEKAAAQERERREAEERERMREEE 321

Query: 652 RKKKEEAARRKQEQEAAKLAKMKIPPSEMFLSETDKYSKFDENGLPTHDM----EGKELS 707
           ++  EE  R K+E++ A   + +I   E   +E  +  K +E            E +E +
Sbjct: 322 KRAAEERQRIKEEEKRAAEERQRIKEEEKRAAEERQRIKEEEKRAAEERQRARAEEEEKA 381

Query: 708 KGQAKKLKKLFEAQEKLYKE 727
           K + +K  K  E ++   +E
Sbjct: 382 KVEEQKRNKQLEEKKHAMQE 401



 Score = 33.1 bits (74), Expect = 0.95
 Identities = 40/152 (26%), Positives = 70/152 (46%), Gaps = 11/152 (7%)

Query: 585 REGVRKIARE-QKVPEILQLSDALRDNILPELGVRFEDHEGLPTVVKLV--DRNTLLKER 641
           RE  ++ A E Q++ E  + +   R  I  E     E+ + +    K    +R     E 
Sbjct: 318 REEEKRAAEERQRIKEEEKRAAEERQRIKEEEKRAAEERQRIKEEEKRAAEERQRARAEE 377

Query: 642 EEKRRVEEEKRKKKEEAARRKQEQEAAKLAKMKIPPSEMFLSETDKYSKFDENGLPTHDM 701
           EEK +VEE+KR K+ E  +   ++   K  K++      +++E     K  E+ L T  +
Sbjct: 378 EEKAKVEEQKRNKQLEEKKHAMQETKIKGEKVEQKIEGKWVNE----KKAQEDKLQTAVL 433

Query: 702 EGKELSKG---QAKKLKKLFEAQEKLYKEYLQ 730
           + +   KG   QAK+ +KL E +    KE ++
Sbjct: 434 KKQGEEKGTKVQAKR-EKLQEDKPTFKKEEIK 464



 Score = 30.4 bits (67), Expect = 6.2
 Identities = 27/85 (31%), Positives = 40/85 (47%), Gaps = 5/85 (5%)

Query: 639 KEREEKRRVEEEKRKKKEEAARRKQEQEAAKLAKMKIPPSEMFLSETDKYSKFDENGLPT 698
           KE E   +VE  KR   EE  RR+ E E+ +  K+K    E  L   +   K +E     
Sbjct: 522 KEAEGAPQVEAGKRL--EELRRRRGETESEEFEKLKQKQQEAALELEELKKKREER---R 576

Query: 699 HDMEGKELSKGQAKKLKKLFEAQEK 723
             +E +E  + Q +  +KL E +EK
Sbjct: 577 KVLEEEEQRRKQEEADRKLREEEEK 601


>gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo
           sapiens]
          Length = 570

 Score = 41.2 bits (95), Expect = 0.003
 Identities = 26/93 (27%), Positives = 51/93 (54%), Gaps = 1/93 (1%)

Query: 638 LKEREEKRRVEEEKRKKKEEAARRKQEQEAAKLAKMKIPPSEMFLSETDKYSKFDENGLP 697
           ++EREEK + +EEK +++EE  RR++E    K  KM+    EM   + +K  + +E    
Sbjct: 297 IQEREEKIQEQEEKIREQEEKMRRQEEMMWEKEEKMR-RQEEMMWEKEEKIRELEEKMHE 355

Query: 698 THDMEGKELSKGQAKKLKKLFEAQEKLYKEYLQ 730
              +  +E  + + +K+++  + QE+  K + Q
Sbjct: 356 QEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQ 388



 Score = 38.5 bits (88), Expect = 0.023
 Identities = 31/108 (28%), Positives = 56/108 (51%), Gaps = 7/108 (6%)

Query: 630 KLVDRNTLLKEREEKRRVEEEKRKKKEEAARRKQEQEAAKLAKMKIPPSEMFLSETDKYS 689
           K+ ++   ++E+EEK R +EE   +KEE  RR++E    K  + KI   E  + E +K  
Sbjct: 303 KIQEQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEK--EEKIRELEEKMHEQEKIR 360

Query: 690 KFDENGLPTHDMEGKELSKGQAKKL----KKLFEAQEKLYKEYLQMAQ 733
           + +E       +  +E  + Q  K+    +K+ E +EK+ +E  +M Q
Sbjct: 361 EQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKI-REQEEMMQ 407



 Score = 37.4 bits (85), Expect = 0.050
 Identities = 36/163 (22%), Positives = 81/163 (49%), Gaps = 13/163 (7%)

Query: 581 LSEFREGVRKIAREQKVPEILQLSDALRDNILPELGVRFEDHEGLPTVVKLVDRNTLLKE 640
           + E  E +R+  +E+K+    ++     + +  +  + +E  E +  + + +     ++E
Sbjct: 304 IQEQEEKIRE--QEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIRE 361

Query: 641 REEKRRVEE---EKRKKKEEAARRKQEQEAAKLAKMKIPPSEMFLSETDKYSKFDENGLP 697
           +EEKR+ EE   E+ K++E+ A+  +++E  +  + KI   E  + E ++     E  + 
Sbjct: 362 QEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMW 421

Query: 698 THD---MEGKELSKGQAKKL----KKLFEAQEKLYKEYLQMAQ 733
             +    E +E  + Q +K+    KK+ E +EK+ +E  +M Q
Sbjct: 422 EQEEEMQEQEEKMRRQEEKIREQEKKIREQEEKI-REQEEMMQ 463



 Score = 36.2 bits (82), Expect = 0.11
 Identities = 32/153 (20%), Positives = 75/153 (49%), Gaps = 23/153 (15%)

Query: 583 EFREGVRKIA-REQKVPEILQLSDALRDNILPELGVRFEDHEGLPTVVKLVDRNTLLKER 641
           + RE  +KI  +E+K+ E        ++ ++ E   +  + EG     K+ ++   ++E+
Sbjct: 440 KIREQEKKIREQEEKIRE--------QEEMMQEQEEKMGEQEG-----KMCEQEAKMQEQ 486

Query: 642 EEKRRVEEEKRKKKEEAARRKQEQEAAKLAKMKIPPSEMFLSETDKYSKFDENGLPTHDM 701
           EEK R +EEK +++E+  R ++E         KI   E  + E ++     E  +   + 
Sbjct: 487 EEKMRRQEEKIREQEKKIREQEE---------KIREQEEMMQEQEEKMWEQEEKMCEQEE 537

Query: 702 EGKELSKGQAKKLKKLFEAQEKLYKEYLQMAQN 734
           + +E  +   ++ +K+ E + +L ++  +M ++
Sbjct: 538 KMQEQEEKMRRQEEKMREQEVRLRQQEEKMQEH 570



 Score = 33.5 bits (75), Expect = 0.73
 Identities = 21/98 (21%), Positives = 51/98 (52%), Gaps = 9/98 (9%)

Query: 630 KLVDRNTLLKEREEKRRVEEEKRKKKEEAARRKQEQEAAKLAKMKIPPSEMFLSETDKYS 689
           K+ ++   ++E+EEK R +EEK +++E+  R ++E         KI   E  + E ++  
Sbjct: 419 KMWEQEEEMQEQEEKMRRQEEKIREQEKKIREQEE---------KIREQEEMMQEQEEKM 469

Query: 690 KFDENGLPTHDMEGKELSKGQAKKLKKLFEAQEKLYKE 727
              E  +   + + +E  +   ++ +K+ E ++K+ ++
Sbjct: 470 GEQEGKMCEQEAKMQEQEEKMRRQEEKIREQEKKIREQ 507


>gi|151301171 RNA polymerase II transcription factor TAFII140 [Homo
           sapiens]
          Length = 929

 Score = 41.2 bits (95), Expect = 0.003
 Identities = 25/74 (33%), Positives = 44/74 (59%), Gaps = 2/74 (2%)

Query: 606 ALRDNILPELGVR-FEDHEGLPTVVKLVDRNTLLKERE-EKRRVEEEKRKKKEEAARRKQ 663
           A+  ++LP L  + FE+ E +    K  D+    K++E EK + E+E+ K+K E  +R++
Sbjct: 676 AMLPSLLPVLPEKLFEEKEKVKEKEKKKDKKEKKKKKEKEKEKKEKEREKEKREREKREK 735

Query: 664 EQEAAKLAKMKIPP 677
           E+E  K  K+K+ P
Sbjct: 736 EKEKHKHEKIKVEP 749



 Score = 30.8 bits (68), Expect = 4.7
 Identities = 36/166 (21%), Positives = 72/166 (43%), Gaps = 28/166 (16%)

Query: 585 REGVRKIAREQKVPEILQLSDALRDNILPELGVRFEDHEGLPTVVKLVDRNTLLKERE-- 642
           +E  ++  RE K P      + L++        + ++ E +   VKL D   + KE+E  
Sbjct: 562 KEKDKETGRETKYP----WKEFLKEEEADPYKFKIKEFEDVDPKVKLKD-GLVRKEKEKH 616

Query: 643 -------EKRRVEEEKRKKKEEAARRKQEQEAAKLAKMKIPPSEMFL-----SETDKYSK 690
                  EK + +++KR+K++   + ++++  A    + +PP E+ L     +   +   
Sbjct: 617 KDKKKDREKGKKDKDKREKEKVKDKGREDKMKAPAPPLVLPPKELALPLFSPATASRVPA 676

Query: 691 FDENGLPT---------HDMEGKELSKGQAKKLKKLFEAQEKLYKE 727
              + LP            ++ KE  K + +K KK  + +EK  KE
Sbjct: 677 MLPSLLPVLPEKLFEEKEKVKEKEKKKDKKEKKKKKEKEKEKKEKE 722


>gi|71061468 centromere protein E [Homo sapiens]
          Length = 2701

 Score = 41.2 bits (95), Expect = 0.003
 Identities = 37/143 (25%), Positives = 67/143 (46%), Gaps = 20/143 (13%)

Query: 594  EQKVPEILQLSDALRDNILPELGVRFED-------HEGLPTVVKLVDRNTLLKEREEKRR 646
            ++KV E+ QL   ++D  L    +  E+       HE L       +  +++KER+  RR
Sbjct: 1843 QKKVSEMEQLKKQIKDQSLTLSKLEIENLNLAQKLHENLE------EMKSVMKERDNLRR 1896

Query: 647  VEEEKRKKKEEAARRKQEQEAAKLAKMKIPPSEMFLSETDKYS------KFDENGLPTHD 700
            VEE  + ++++     QE +A  L   +   +   LS+  K +      K  E  +   D
Sbjct: 1897 VEETLKLERDQLKESLQETKARDLEIQQELKTARMLSKEHKETVDKLREKISEKTIQISD 1956

Query: 701  MEGKELSKGQAKKLKKLFEAQEK 723
            ++ K+L K + +  KK+ E Q+K
Sbjct: 1957 IQ-KDLDKSKDELQKKIQELQKK 1978


>gi|22035606 mitogen-activated protein kinase kinase kinase kinase 4
           isoform 3 [Homo sapiens]
          Length = 1212

 Score = 41.2 bits (95), Expect = 0.003
 Identities = 35/139 (25%), Positives = 70/139 (50%), Gaps = 15/139 (10%)

Query: 549 GAVEEDSSLGFPVGGPGTSLSL--EATVM-PYLQVLSEFREGVRKIAREQKVPEI-LQLS 604
           G+ EE+  +    G P + +++  E+T+   +L++  E +E    + R+Q + E  L+  
Sbjct: 325 GSEEEEEEVPEQEGEPSSIVNVPGESTLRRDFLRLQQENKERSEALRRQQLLQEQQLREQ 384

Query: 605 DALRDNILPELGVRFEDHEGLPTVV-----------KLVDRNTLLKEREEKRRVEEEKRK 653
           +  +  +L E   R E  +     +           +  +R    +E+EEKRR+EE +R+
Sbjct: 385 EEYKRQLLAERQKRIEQQKEQRRRLEEQQRREREARRQQEREQRRREQEEKRRLEELERR 444

Query: 654 KKEEAARRKQEQEAAKLAK 672
           +KEE  RR+ E+E  ++ +
Sbjct: 445 RKEEEERRRAEEEKRRVER 463



 Score = 33.5 bits (75), Expect = 0.73
 Identities = 17/34 (50%), Positives = 24/34 (70%), Gaps = 2/34 (5%)

Query: 639 KEREEKRRVEEEKRK--KKEEAARRKQEQEAAKL 670
           KE EE+RR EEEKR+  +++E  RR+ E+E   L
Sbjct: 446 KEEEERRRAEEEKRRVEREQEYIRRQLEEEQRHL 479



 Score = 32.0 bits (71), Expect = 2.1
 Identities = 14/29 (48%), Positives = 22/29 (75%)

Query: 638 LKEREEKRRVEEEKRKKKEEAARRKQEQE 666
           L+E E +R+ EEE+R+ +EE  R ++EQE
Sbjct: 438 LEELERRRKEEEERRRAEEEKRRVEREQE 466


>gi|22035602 mitogen-activated protein kinase kinase kinase kinase 4
           isoform 1 [Homo sapiens]
          Length = 1166

 Score = 41.2 bits (95), Expect = 0.003
 Identities = 35/139 (25%), Positives = 70/139 (50%), Gaps = 15/139 (10%)

Query: 549 GAVEEDSSLGFPVGGPGTSLSL--EATVM-PYLQVLSEFREGVRKIAREQKVPEI-LQLS 604
           G+ EE+  +    G P + +++  E+T+   +L++  E +E    + R+Q + E  L+  
Sbjct: 325 GSEEEEEEVPEQEGEPSSIVNVPGESTLRRDFLRLQQENKERSEALRRQQLLQEQQLREQ 384

Query: 605 DALRDNILPELGVRFEDHEGLPTVV-----------KLVDRNTLLKEREEKRRVEEEKRK 653
           +  +  +L E   R E  +     +           +  +R    +E+EEKRR+EE +R+
Sbjct: 385 EEYKRQLLAERQKRIEQQKEQRRRLEEQQRREREARRQQEREQRRREQEEKRRLEELERR 444

Query: 654 KKEEAARRKQEQEAAKLAK 672
           +KEE  RR+ E+E  ++ +
Sbjct: 445 RKEEEERRRAEEEKRRVER 463



 Score = 33.5 bits (75), Expect = 0.73
 Identities = 17/34 (50%), Positives = 24/34 (70%), Gaps = 2/34 (5%)

Query: 639 KEREEKRRVEEEKRK--KKEEAARRKQEQEAAKL 670
           KE EE+RR EEEKR+  +++E  RR+ E+E   L
Sbjct: 446 KEEEERRRAEEEKRRVEREQEYIRRQLEEEQRHL 479



 Score = 32.0 bits (71), Expect = 2.1
 Identities = 14/29 (48%), Positives = 22/29 (75%)

Query: 638 LKEREEKRRVEEEKRKKKEEAARRKQEQE 666
           L+E E +R+ EEE+R+ +EE  R ++EQE
Sbjct: 438 LEELERRRKEEEERRRAEEEKRRVEREQE 466


>gi|22035604 mitogen-activated protein kinase kinase kinase kinase 4
           isoform 2 [Homo sapiens]
          Length = 1320

 Score = 41.2 bits (95), Expect = 0.003
 Identities = 35/139 (25%), Positives = 70/139 (50%), Gaps = 15/139 (10%)

Query: 549 GAVEEDSSLGFPVGGPGTSLSL--EATVM-PYLQVLSEFREGVRKIAREQKVPEI-LQLS 604
           G+ EE+  +    G P + +++  E+T+   +L++  E +E    + R+Q + E  L+  
Sbjct: 325 GSEEEEEEVPEQEGEPSSIVNVPGESTLRRDFLRLQQENKERSEALRRQQLLQEQQLREQ 384

Query: 605 DALRDNILPELGVRFEDHEGLPTVV-----------KLVDRNTLLKEREEKRRVEEEKRK 653
           +  +  +L E   R E  +     +           +  +R    +E+EEKRR+EE +R+
Sbjct: 385 EEYKRQLLAERQKRIEQQKEQRRRLEEQQRREREARRQQEREQRRREQEEKRRLEELERR 444

Query: 654 KKEEAARRKQEQEAAKLAK 672
           +KEE  RR+ E+E  ++ +
Sbjct: 445 RKEEEERRRAEEEKRRVER 463



 Score = 33.5 bits (75), Expect = 0.73
 Identities = 17/34 (50%), Positives = 24/34 (70%), Gaps = 2/34 (5%)

Query: 639 KEREEKRRVEEEKRK--KKEEAARRKQEQEAAKL 670
           KE EE+RR EEEKR+  +++E  RR+ E+E   L
Sbjct: 446 KEEEERRRAEEEKRRVEREQEYIRRQLEEEQRHL 479



 Score = 32.0 bits (71), Expect = 2.1
 Identities = 14/29 (48%), Positives = 22/29 (75%)

Query: 638 LKEREEKRRVEEEKRKKKEEAARRKQEQE 666
           L+E E +R+ EEE+R+ +EE  R ++EQE
Sbjct: 438 LEELERRRKEEEERRRAEEEKRRVEREQE 466


>gi|239508778 PREDICTED: hypothetical protein, partial [Homo
           sapiens]
          Length = 123

 Score = 40.8 bits (94), Expect = 0.005
 Identities = 25/89 (28%), Positives = 49/89 (55%), Gaps = 4/89 (4%)

Query: 639 KEREEKRRVEEEKRKKKEEAARRKQEQEAAKLAKMKIPPSEMFLSETDKYSKFDENGLPT 698
           KE+ +++R E+EK+KK +E  +RK+++E  K  K K    +    E ++  + +E     
Sbjct: 30  KEKRKEKRKEKEKKKKTKETEKRKEKEEEEKKRKRKRKKKK----EEEEREEEEEEEEEE 85

Query: 699 HDMEGKELSKGQAKKLKKLFEAQEKLYKE 727
            + E KE  + + KK K+  + +E+  K+
Sbjct: 86  KEEEEKEEGRRRKKKKKRRRKEEEEEKKK 114



 Score = 32.3 bits (72), Expect = 1.6
 Identities = 13/36 (36%), Positives = 25/36 (69%)

Query: 639 KEREEKRRVEEEKRKKKEEAARRKQEQEAAKLAKMK 674
           +E+EE+ + E  +RKKK++  R+++E+E  K  + K
Sbjct: 84  EEKEEEEKEEGRRRKKKKKRRRKEEEEEKKKKRRRK 119



 Score = 30.8 bits (68), Expect = 4.7
 Identities = 15/39 (38%), Positives = 26/39 (66%), Gaps = 3/39 (7%)

Query: 639 KEREEKRRVEEEK---RKKKEEAARRKQEQEAAKLAKMK 674
           +E EE+ + EEEK   R++K++  RR++E+E  K  K +
Sbjct: 79  EEEEEEEKEEEEKEEGRRRKKKKKRRRKEEEEEKKKKRR 117


>gi|12711676 UPF3 regulator of nonsense transcripts homolog A
           isoform hUpf3p [Homo sapiens]
          Length = 476

 Score = 39.7 bits (91), Expect = 0.010
 Identities = 27/88 (30%), Positives = 44/88 (50%), Gaps = 4/88 (4%)

Query: 630 KLVDRNTLLKEREEKRRVEEEKRKKKEEAARRKQEQEAAKL----AKMKIPPSEMFLSET 685
           KL  +    ++REE+RR E EK++ +EE  RR++E+E  K      + KI   E+ +   
Sbjct: 225 KLEKQRIREEKREERRRRELEKKRLREEEKRRRREEERCKKKETDKQKKIAEKEVRIKLL 284

Query: 686 DKYSKFDENGLPTHDMEGKELSKGQAKK 713
            K  K +E         G+E+  G  K+
Sbjct: 285 KKPEKGEEPTTEKPKERGEEIDTGGGKQ 312


>gi|18375525 UPF3 regulator of nonsense transcripts homolog A
           isoform hUpf3pdelta [Homo sapiens]
          Length = 443

 Score = 39.7 bits (91), Expect = 0.010
 Identities = 27/88 (30%), Positives = 44/88 (50%), Gaps = 4/88 (4%)

Query: 630 KLVDRNTLLKEREEKRRVEEEKRKKKEEAARRKQEQEAAKL----AKMKIPPSEMFLSET 685
           KL  +    ++REE+RR E EK++ +EE  RR++E+E  K      + KI   E+ +   
Sbjct: 192 KLEKQRIREEKREERRRRELEKKRLREEEKRRRREEERCKKKETDKQKKIAEKEVRIKLL 251

Query: 686 DKYSKFDENGLPTHDMEGKELSKGQAKK 713
            K  K +E         G+E+  G  K+
Sbjct: 252 KKPEKGEEPTTEKPKERGEEIDTGGGKQ 279


>gi|15826852 acyl-Coenzyme A binding domain containing 3 [Homo
           sapiens]
          Length = 528

 Score = 39.3 bits (90), Expect = 0.013
 Identities = 27/94 (28%), Positives = 50/94 (53%), Gaps = 11/94 (11%)

Query: 638 LKEREEKRRVEEEKRKKKEEAARRKQEQEAAKLAKMKIPPSEMFLSETD-KYSKFDENGL 696
           L++ EEKRR EEE+R ++EE  RR+ E+E  +L + K        S+T  ++ ++     
Sbjct: 207 LQKEEEKRRREEEERLRREEEERRRIEEERLRLEQQKQQIMAALNSQTAVQFQQYAAQQY 266

Query: 697 PTHDMEGKELSKGQAKKLKKLFEAQEKLYKEYLQ 730
           P +  + + L +          + QE+ Y++Y+Q
Sbjct: 267 PGNYEQQQILIR----------QLQEQHYQQYMQ 290



 Score = 35.0 bits (79), Expect = 0.25
 Identities = 17/30 (56%), Positives = 24/30 (80%), Gaps = 2/30 (6%)

Query: 639 KEREEKRRVEEEKRKK--KEEAARRKQEQE 666
           KE EE+RR EEE+R++  KEE  RR++E+E
Sbjct: 191 KEEEERRRREEEERERLQKEEEKRRREEEE 220



 Score = 34.7 bits (78), Expect = 0.33
 Identities = 14/31 (45%), Positives = 23/31 (74%)

Query: 639 KEREEKRRVEEEKRKKKEEAARRKQEQEAAK 669
           KE +EK+R EEE+R+++EE  R + ++E  K
Sbjct: 183 KEEQEKKRKEEEERRRREEEERERLQKEEEK 213



 Score = 32.7 bits (73), Expect = 1.2
 Identities = 14/39 (35%), Positives = 28/39 (71%), Gaps = 2/39 (5%)

Query: 639 KEREEKRRV--EEEKRKKKEEAARRKQEQEAAKLAKMKI 675
           +E EE+ R+  EEEKR+++EE   R++E+E  ++ + ++
Sbjct: 199 REEEERERLQKEEEKRRREEEERLRREEEERRRIEEERL 237



 Score = 31.2 bits (69), Expect = 3.6
 Identities = 12/25 (48%), Positives = 20/25 (80%)

Query: 648 EEEKRKKKEEAARRKQEQEAAKLAK 672
           E+EK++K+EE  RR++E+E  +L K
Sbjct: 185 EQEKKRKEEEERRRREEEERERLQK 209


>gi|102467235 inner centromere protein antigens 135/155kDa isoform 1
           [Homo sapiens]
          Length = 918

 Score = 39.3 bits (90), Expect = 0.013
 Identities = 28/106 (26%), Positives = 51/106 (48%), Gaps = 8/106 (7%)

Query: 630 KLVDRNTLLKEREEKRRVEEEKRKKKEEAARRKQEQ--------EAAKLAKMKIPPSEMF 681
           K  +   L ++RE++RR +E + +++ E  RR+QE+        E  +  + +   +E  
Sbjct: 677 KAAEAKRLAEQREQERREQERREQERREQERREQERREQERQLAEQERRREQERLQAERE 736

Query: 682 LSETDKYSKFDENGLPTHDMEGKELSKGQAKKLKKLFEAQEKLYKE 727
           L E +K  +  +  L     E K+  + Q    ++L E QEK  KE
Sbjct: 737 LQEREKALRLQKEQLQRELEEKKKKEEQQRLAERQLQEEQEKKAKE 782



 Score = 38.1 bits (87), Expect = 0.030
 Identities = 37/145 (25%), Positives = 69/145 (47%), Gaps = 18/145 (12%)

Query: 590 KIAREQKVPEILQLSDALRDNILPELGVRFEDHEGLPTVVKLVDRNTLLKEREEKRRVEE 649
           K+ RE+++ ++LQ  + +         ++ E  + +      +D  T   E+ ++ R+ E
Sbjct: 571 KLKREERLRKVLQARERVEQ-------MKEEKKKQIEQKFAQIDEKT---EKAKEERLAE 620

Query: 650 EKRKKKEEA-------ARRKQEQEAAKLAKMKIPPSEMFLSETDKYSKFDENGLPTHDME 702
           EK KKK  A       ARRKQE+EA +L  ++    E    E  +  K +E        E
Sbjct: 621 EKAKKKAAAKKMEEVEARRKQEEEARRLRWLQQEEEERRHQELLQKKKEEEQERLRKAAE 680

Query: 703 GKELSKGQAKKLKKLFEAQEKLYKE 727
            K L++ Q ++ ++  E +E+  +E
Sbjct: 681 AKRLAE-QREQERREQERREQERRE 704



 Score = 31.2 bits (69), Expect = 3.6
 Identities = 31/110 (28%), Positives = 49/110 (44%), Gaps = 14/110 (12%)

Query: 629 VKLVDRNTLLKEREEKRRVEEEKRKKK-----------EEAARRKQEQEAAKLAKMKIPP 677
           VKL     L K  + + RVE+ K +KK           E+  + K+E+ A + AK K   
Sbjct: 570 VKLKREERLRKVLQARERVEQMKEEKKKQIEQKFAQIDEKTEKAKEERLAEEKAKKKAAA 629

Query: 678 SEMFLSETDKYSKFDENGLPTHDMEGKELSKGQAKKL-KKLFEAQEKLYK 726
            +M   E +   K +E       ++ +E  +   + L KK  E QE+L K
Sbjct: 630 KKM--EEVEARRKQEEEARRLRWLQQEEEERRHQELLQKKKEEEQERLRK 677



 Score = 31.2 bits (69), Expect = 3.6
 Identities = 23/102 (22%), Positives = 50/102 (49%), Gaps = 6/102 (5%)

Query: 638 LKEREEKRRVEEEKRKKKEEAARRKQEQEAAKLAKMKIPPSEMFLSETDKYSKFDENGLP 697
           L++  E +R+ E++ +++ E  RR+QE+   +  + +    E  L+E ++  + +     
Sbjct: 675 LRKAAEAKRLAEQREQERREQERREQERREQERREQERREQERQLAEQERRREQERLQAE 734

Query: 698 THDMEGKELSKGQAKKL------KKLFEAQEKLYKEYLQMAQ 733
               E ++  + Q ++L      KK  E Q++L +  LQ  Q
Sbjct: 735 RELQEREKALRLQKEQLQRELEEKKKKEEQQRLAERQLQEEQ 776



 Score = 30.8 bits (68), Expect = 4.7
 Identities = 23/94 (24%), Positives = 46/94 (48%), Gaps = 7/94 (7%)

Query: 640 EREEKRRVEEEKRKKKEEAARRKQE------QEAAKLAKMKIPPSEMFLSETDKYSKFDE 693
           E+  +++VEE+KR++ EE   +++E      Q   ++ +MK    +    +  +  +  E
Sbjct: 552 EQLRRQKVEEDKRRRLEEVKLKREERLRKVLQARERVEQMKEEKKKQIEQKFAQIDEKTE 611

Query: 694 NGLPTHDMEGKELSKGQAKKLKKLFEAQEKLYKE 727
                   E K   K  AKK++++ EA+ K  +E
Sbjct: 612 KAKEERLAEEKAKKKAAAKKMEEV-EARRKQEEE 644



 Score = 30.4 bits (67), Expect = 6.2
 Identities = 20/58 (34%), Positives = 33/58 (56%), Gaps = 3/58 (5%)

Query: 618 RFEDHEGLPTVVKLVDRNTLLKEREEKRRVEEEKRKKKEE---AARRKQEQEAAKLAK 672
           R  + E L    +L +R   L+ ++E+ + E E++KKKEE    A R+ ++E  K AK
Sbjct: 724 RRREQERLQAERELQEREKALRLQKEQLQRELEEKKKKEEQQRLAERQLQEEQEKKAK 781


>gi|102467242 inner centromere protein antigens 135/155kDa isoform 2
           [Homo sapiens]
          Length = 914

 Score = 39.3 bits (90), Expect = 0.013
 Identities = 28/106 (26%), Positives = 51/106 (48%), Gaps = 8/106 (7%)

Query: 630 KLVDRNTLLKEREEKRRVEEEKRKKKEEAARRKQEQ--------EAAKLAKMKIPPSEMF 681
           K  +   L ++RE++RR +E + +++ E  RR+QE+        E  +  + +   +E  
Sbjct: 673 KAAEAKRLAEQREQERREQERREQERREQERREQERREQERQLAEQERRREQERLQAERE 732

Query: 682 LSETDKYSKFDENGLPTHDMEGKELSKGQAKKLKKLFEAQEKLYKE 727
           L E +K  +  +  L     E K+  + Q    ++L E QEK  KE
Sbjct: 733 LQEREKALRLQKEQLQRELEEKKKKEEQQRLAERQLQEEQEKKAKE 778



 Score = 38.1 bits (87), Expect = 0.030
 Identities = 37/145 (25%), Positives = 69/145 (47%), Gaps = 18/145 (12%)

Query: 590 KIAREQKVPEILQLSDALRDNILPELGVRFEDHEGLPTVVKLVDRNTLLKEREEKRRVEE 649
           K+ RE+++ ++LQ  + +         ++ E  + +      +D  T   E+ ++ R+ E
Sbjct: 567 KLKREERLRKVLQARERVEQ-------MKEEKKKQIEQKFAQIDEKT---EKAKEERLAE 616

Query: 650 EKRKKKEEA-------ARRKQEQEAAKLAKMKIPPSEMFLSETDKYSKFDENGLPTHDME 702
           EK KKK  A       ARRKQE+EA +L  ++    E    E  +  K +E        E
Sbjct: 617 EKAKKKAAAKKMEEVEARRKQEEEARRLRWLQQEEEERRHQELLQKKKEEEQERLRKAAE 676

Query: 703 GKELSKGQAKKLKKLFEAQEKLYKE 727
            K L++ Q ++ ++  E +E+  +E
Sbjct: 677 AKRLAE-QREQERREQERREQERRE 700



 Score = 31.2 bits (69), Expect = 3.6
 Identities = 31/110 (28%), Positives = 49/110 (44%), Gaps = 14/110 (12%)

Query: 629 VKLVDRNTLLKEREEKRRVEEEKRKKK-----------EEAARRKQEQEAAKLAKMKIPP 677
           VKL     L K  + + RVE+ K +KK           E+  + K+E+ A + AK K   
Sbjct: 566 VKLKREERLRKVLQARERVEQMKEEKKKQIEQKFAQIDEKTEKAKEERLAEEKAKKKAAA 625

Query: 678 SEMFLSETDKYSKFDENGLPTHDMEGKELSKGQAKKL-KKLFEAQEKLYK 726
            +M   E +   K +E       ++ +E  +   + L KK  E QE+L K
Sbjct: 626 KKM--EEVEARRKQEEEARRLRWLQQEEEERRHQELLQKKKEEEQERLRK 673



 Score = 31.2 bits (69), Expect = 3.6
 Identities = 23/102 (22%), Positives = 50/102 (49%), Gaps = 6/102 (5%)

Query: 638 LKEREEKRRVEEEKRKKKEEAARRKQEQEAAKLAKMKIPPSEMFLSETDKYSKFDENGLP 697
           L++  E +R+ E++ +++ E  RR+QE+   +  + +    E  L+E ++  + +     
Sbjct: 671 LRKAAEAKRLAEQREQERREQERREQERREQERREQERREQERQLAEQERRREQERLQAE 730

Query: 698 THDMEGKELSKGQAKKL------KKLFEAQEKLYKEYLQMAQ 733
               E ++  + Q ++L      KK  E Q++L +  LQ  Q
Sbjct: 731 RELQEREKALRLQKEQLQRELEEKKKKEEQQRLAERQLQEEQ 772



 Score = 30.8 bits (68), Expect = 4.7
 Identities = 23/94 (24%), Positives = 46/94 (48%), Gaps = 7/94 (7%)

Query: 640 EREEKRRVEEEKRKKKEEAARRKQE------QEAAKLAKMKIPPSEMFLSETDKYSKFDE 693
           E+  +++VEE+KR++ EE   +++E      Q   ++ +MK    +    +  +  +  E
Sbjct: 548 EQLRRQKVEEDKRRRLEEVKLKREERLRKVLQARERVEQMKEEKKKQIEQKFAQIDEKTE 607

Query: 694 NGLPTHDMEGKELSKGQAKKLKKLFEAQEKLYKE 727
                   E K   K  AKK++++ EA+ K  +E
Sbjct: 608 KAKEERLAEEKAKKKAAAKKMEEV-EARRKQEEE 640



 Score = 30.4 bits (67), Expect = 6.2
 Identities = 20/58 (34%), Positives = 33/58 (56%), Gaps = 3/58 (5%)

Query: 618 RFEDHEGLPTVVKLVDRNTLLKEREEKRRVEEEKRKKKEE---AARRKQEQEAAKLAK 672
           R  + E L    +L +R   L+ ++E+ + E E++KKKEE    A R+ ++E  K AK
Sbjct: 720 RRREQERLQAERELQEREKALRLQKEQLQRELEEKKKKEEQQRLAERQLQEEQEKKAK 777


>gi|108773810 leucyl-tRNA synthetase [Homo sapiens]
          Length = 1176

 Score = 38.9 bits (89), Expect = 0.017
 Identities = 27/75 (36%), Positives = 37/75 (49%), Gaps = 2/75 (2%)

Query: 350 MDIHGGGFDLRFPHHDNELAQSEAYF--ENDCWVRYFLHTGHLTIAGCKMSKSLKNFITI 407
           +D+   G DL   H    L    A +  ++D W       GHL +   KMSKS  NF+T+
Sbjct: 668 VDLRVSGKDLVPNHLSYYLYNHVAMWPEQSDKWPTAVRANGHLLLNSEKMSKSTGNFLTL 727

Query: 408 KDALKKHSARQLRLA 422
             A+ K SA  +RLA
Sbjct: 728 TQAIDKFSADGMRLA 742


>gi|50513245 chromatin assembly factor 1, subunit A (p150) [Homo
           sapiens]
          Length = 956

 Score = 38.9 bits (89), Expect = 0.017
 Identities = 24/98 (24%), Positives = 53/98 (54%), Gaps = 1/98 (1%)

Query: 637 LLKEREEKRRVEEEKRKKKEEAARRKQEQEAAKLAKMKIPPSEMFLSETDKYSKFDENGL 696
           L  EREEK +++EE ++ KEEA ++K+E++  K  + +    +    + +K    +E   
Sbjct: 350 LRAEREEKEKLKEEAKRAKEEAKKKKEEEKELKEKERREKREKDEKEKAEKQRLKEERRK 409

Query: 697 PTHD-MEGKELSKGQAKKLKKLFEAQEKLYKEYLQMAQ 733
              + +E K   K + ++ K+L E ++++  E  ++ +
Sbjct: 410 ERQEALEAKLEEKRKKEEEKRLREEEKRIKAEKAEITR 447



 Score = 34.7 bits (78), Expect = 0.33
 Identities = 38/175 (21%), Positives = 72/175 (41%), Gaps = 15/175 (8%)

Query: 550 AVEEDSSLGFPVGGPG-----TSLSLEATVMPYLQVLSEFREGVRKIAREQKVPEILQLS 604
           ++   SS   P G P      +S S   T  P  ++  +F +G  +  + +   +  +L 
Sbjct: 286 SLSSPSSTSSPEGPPAPPKQHSSTSPFPTSTPLRRITKKFVKGSTEKNKLRLQRDQERLG 345

Query: 605 DALRDNILPELGVRFEDHEGLPTVVKLVDRNTLLKEREEKRRVEEEKRKKKEEAARRKQE 664
             L+      L    E+ E L    K        K+ EEK   E+E+R+K+E+  + K E
Sbjct: 346 KQLK------LRAEREEKEKLKEEAKRAKEEAKKKKEEEKELKEKERREKREKDEKEKAE 399

Query: 665 QEAAKLAKMKIPPSEMFLSETDKYSKFDENGLPTHDMEGKELSKGQAKKLKKLFE 719
           ++  K  + K     +     +K  K +E  L     E ++  K +  ++ + F+
Sbjct: 400 KQRLKEERRKERQEALEAKLEEKRKKEEEKRL----REEEKRIKAEKAEITRFFQ 450


>gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo
           sapiens]
          Length = 750

 Score = 38.5 bits (88), Expect = 0.023
 Identities = 25/98 (25%), Positives = 54/98 (55%), Gaps = 2/98 (2%)

Query: 630 KLVDRNTLLKEREEKRRVEEEKRKKKEEAARRKQEQEAAKLAKMKIPPSEMFLSETDKYS 689
           K+ +    ++E+EEK R +EEK +++EE  RR++E    K  KM+    E  + E ++  
Sbjct: 308 KIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMR--RQEEMMWEKEEKM 365

Query: 690 KFDENGLPTHDMEGKELSKGQAKKLKKLFEAQEKLYKE 727
           +  E  +   + + +   +   +K +K+ E +EK++++
Sbjct: 366 RRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQ 403



 Score = 37.0 bits (84), Expect = 0.066
 Identities = 23/109 (21%), Positives = 59/109 (54%), Gaps = 5/109 (4%)

Query: 630 KLVDRNTLLKEREEKRRVEEEKRKKKEEAARRKQEQEAAKLAKM-----KIPPSEMFLSE 684
           K+ ++   ++E+EEK R +EEK +++EE  + ++E+   +  KM     K+   E  +  
Sbjct: 613 KIREQEEKIQEQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEETMWR 672

Query: 685 TDKYSKFDENGLPTHDMEGKELSKGQAKKLKKLFEAQEKLYKEYLQMAQ 733
            ++  +  E  +   + + +E  +   ++ +K++E +EK+ ++  +M +
Sbjct: 673 QEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQE 721



 Score = 35.8 bits (81), Expect = 0.15
 Identities = 23/95 (24%), Positives = 50/95 (52%), Gaps = 5/95 (5%)

Query: 638 LKEREEKRRVEEEKRKKKEEAARRKQE-----QEAAKLAKMKIPPSEMFLSETDKYSKFD 692
           ++E+EEKR+ +EEK  K+EE  R ++E     +E  +  + KI   E    E ++     
Sbjct: 593 IREQEEKRQEQEEKMWKQEEKIREQEEKIQEQEEKIREQEEKIREQEEMTQEQEEKMGEQ 652

Query: 693 ENGLPTHDMEGKELSKGQAKKLKKLFEAQEKLYKE 727
           E  +   + + +E  +   ++ +K+ E ++K+ ++
Sbjct: 653 EEKMCEQEEKMQEQEETMWRQEEKIREQEKKIREQ 687



 Score = 33.5 bits (75), Expect = 0.73
 Identities = 23/109 (21%), Positives = 56/109 (51%), Gaps = 5/109 (4%)

Query: 630 KLVDRNTLLKEREEKRRVEEEKRKKKEEAARRKQEQEAAKLAKM-----KIPPSEMFLSE 684
           K+  +   ++E+EEK + +EEK +++EE  R ++E    +  KM     K+   E  + E
Sbjct: 606 KMWKQEEKIREQEEKIQEQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQE 665

Query: 685 TDKYSKFDENGLPTHDMEGKELSKGQAKKLKKLFEAQEKLYKEYLQMAQ 733
            ++     E  +   + + +E  +   ++ + + E +EK++++  +M +
Sbjct: 666 QEETMWRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCE 714



 Score = 33.1 bits (74), Expect = 0.95
 Identities = 25/93 (26%), Positives = 49/93 (52%), Gaps = 4/93 (4%)

Query: 638 LKEREEKRRVEEEKRKKKEEAARRKQE---QEAAKLAKMKIPPSEMFLSETDKYSKFDEN 694
           ++E+EEK R +EEK  ++EE  R ++E   +E     + KI   E    + DK  + +E 
Sbjct: 519 IREQEEKIREQEEKMWRQEEKIREQEEMWREEEKMHEQEKIWEEEKRQEQEDKMWRQEEK 578

Query: 695 GLPTHDMEGKELSKGQAKKLKKLFEAQEKLYKE 727
                +   ++  K + ++ K+  E +EK++K+
Sbjct: 579 IREQEEKVWRQEEKIREQEEKRQ-EQEEKMWKQ 610



 Score = 33.1 bits (74), Expect = 0.95
 Identities = 22/98 (22%), Positives = 50/98 (51%), Gaps = 9/98 (9%)

Query: 630 KLVDRNTLLKEREEKRRVEEEKRKKKEEAARRKQEQEAAKLAKMKIPPSEMFLSETDKYS 689
           K+ ++   +  +EEK R +EEKR+++EE   +++E         KI   E  + E ++  
Sbjct: 578 KIREQEEKVWRQEEKIREQEEKRQEQEEKMWKQEE---------KIREQEEKIQEQEEKI 628

Query: 690 KFDENGLPTHDMEGKELSKGQAKKLKKLFEAQEKLYKE 727
           +  E  +   +   +E  +   ++ +K+ E +EK+ ++
Sbjct: 629 REQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQ 666



 Score = 32.0 bits (71), Expect = 2.1
 Identities = 23/96 (23%), Positives = 52/96 (54%), Gaps = 8/96 (8%)

Query: 637 LLKEREEKRRVEEEKRKKKEEAARRKQEQEAAKLAKM-----KIPPSEMFLSETDKYSKF 691
           L ++  E+ ++ E++ K++EE   R+QE+   + AKM     KI   E  + E +K    
Sbjct: 396 LEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMWR 455

Query: 692 DENGLPTHDMEGKELSKGQAKKLKKLFEAQEKLYKE 727
            E  +  H+ E K   + + ++ ++++  +EK++++
Sbjct: 456 QEEKI--HEQE-KIREEEKRQEQEEMWRQEEKIHEQ 488



 Score = 30.8 bits (68), Expect = 4.7
 Identities = 25/95 (26%), Positives = 48/95 (50%), Gaps = 8/95 (8%)

Query: 638 LKEREEKRRVEEEKRKKKEEAARRKQEQEAAKLAKM-----KIPPSEMFLSETDKYSKFD 692
           + E+EEK R +EEK  ++EE  R ++E+   +  KM     KI   E    E +K  + +
Sbjct: 498 MHEQEEKIRKQEEKVWRQEEKIREQEEKIREQEEKMWRQEEKIREQEEMWREEEKMHEQE 557

Query: 693 ENGLPTHDMEGKELSKGQAKKLKKLFEAQEKLYKE 727
           +        E ++    Q +K++   E +EK++++
Sbjct: 558 KIWEEEKRQEQEDKMWRQEEKIR---EQEEKVWRQ 589



 Score = 30.0 bits (66), Expect = 8.1
 Identities = 22/100 (22%), Positives = 52/100 (52%), Gaps = 3/100 (3%)

Query: 630 KLVDRNTLLKEREEKRRVEEEK--RKKKEEAARRKQEQEAAKLAKMKIPPSEMFLSETDK 687
           K+ ++   ++E+E+K   +EEK   ++K     ++QEQE     + KI   E    + +K
Sbjct: 438 KIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIHEQEEIWRQKEK 497

Query: 688 YSKFDENGLPTHDMEGKELSKGQAKKLKKLFEAQEKLYKE 727
             + +E      +   ++  K + ++ +K+ E +EK++++
Sbjct: 498 MHEQEEKIRKQEEKVWRQEEKIREQE-EKIREQEEKMWRQ 536


>gi|223634475 golgi autoantigen, golgin subfamily a, 6D [Homo
           sapiens]
          Length = 693

 Score = 38.1 bits (87), Expect = 0.030
 Identities = 21/90 (23%), Positives = 49/90 (54%)

Query: 638 LKEREEKRRVEEEKRKKKEEAARRKQEQEAAKLAKMKIPPSEMFLSETDKYSKFDENGLP 697
           L  +E+K+R++E++   +E+ A+R +EQE       ++   +  L E  +  +  E  L 
Sbjct: 330 LLSKEQKQRLQEQEEMLREQEAQRVREQERLCEQNERLREQQKTLQEQGERLRKQEQRLR 389

Query: 698 THDMEGKELSKGQAKKLKKLFEAQEKLYKE 727
             +   ++  +   K+ K+L++ +E+L+K+
Sbjct: 390 KQEERLRKEEERLQKQEKRLWDQEERLWKK 419



 Score = 37.4 bits (85), Expect = 0.050
 Identities = 29/102 (28%), Positives = 54/102 (52%), Gaps = 3/102 (2%)

Query: 638 LKEREEKRRVEEEKRKKKEEAARRKQEQEAAKLAKMKIPPSEMFLSETDKYSK-FDENGL 696
           L+++EE+ R EEE+ +K+E+    ++E+   K  +++     + LS+  K  K   E   
Sbjct: 388 LRKQEERLRKEEERLQKQEKRLWDQEERLWKKEERLQKQEERLALSQNHKLDKQLAEPQC 447

Query: 697 PTHDMEGKELSKGQAKKLKKLFEAQEKLYKEYLQMAQNGSFQ 738
              D+  ++ S  Q ++  K  E QEKL +E+L+ A   + Q
Sbjct: 448 SFEDLNNEKKSALQLEQQVK--ELQEKLDEEHLEAASQRNQQ 487


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.317    0.134    0.394 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 27,674,889
Number of Sequences: 37866
Number of extensions: 1267014
Number of successful extensions: 14053
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 199
Number of HSP's successfully gapped in prelim test: 226
Number of HSP's that attempted gapping in prelim test: 9157
Number of HSP's gapped (non-prelim): 2808
length of query: 738
length of database: 18,247,518
effective HSP length: 110
effective length of query: 628
effective length of database: 14,082,258
effective search space: 8843658024
effective search space used: 8843658024
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.