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Search of human proteins with 62234438
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|62234438 Notchless gene homolog isoform b [Homo sapiens]
(193 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|62234438 Notchless gene homolog isoform b [Homo sapiens] 388 e-108
gi|62234461 Notchless gene homolog isoform a [Homo sapiens] 388 e-108
gi|16554629 WD repeat domain 5 [Homo sapiens] 105 2e-23
gi|16554627 WD repeat domain 5 [Homo sapiens] 105 2e-23
gi|23199987 WD repeat domain 5B [Homo sapiens] 103 9e-23
gi|83779014 katanin p80 subunit B 1 [Homo sapiens] 97 8e-21
gi|7657439 PCAF associated factor 65 beta isoform a [Homo sapiens] 96 2e-20
gi|113865883 WD repeat domain 38 [Homo sapiens] 95 3e-20
gi|21071067 TBP-associated factor 5 [Homo sapiens] 94 7e-20
gi|32189425 WD repeat domain 69 [Homo sapiens] 94 7e-20
gi|24431950 PRP4 pre-mRNA processing factor 4 homolog [Homo sapi... 93 2e-19
gi|4557741 platelet-activating factor acetylhydrolase, isoform I... 91 5e-19
gi|239787760 WD repeat domain 51A isoform 2 [Homo sapiens] 89 2e-18
gi|239787754 WD repeat domain 51A isoform 1 [Homo sapiens] 89 2e-18
gi|5174447 guanine nucleotide binding protein (G protein), beta ... 88 4e-18
gi|26665869 WD repeat domain 51B [Homo sapiens] 88 4e-18
gi|239787764 WD repeat domain 51A isoform 3 [Homo sapiens] 87 7e-18
gi|19913371 transducin (beta)-like 1 X-linked receptor 1 [Homo s... 87 9e-18
gi|4505731 peroxisomal biogenesis factor 7 [Homo sapiens] 86 3e-17
gi|213021190 transducin beta-like 1X isoform b [Homo sapiens] 86 3e-17
gi|213021188 transducin beta-like 1X isoform b [Homo sapiens] 86 3e-17
gi|213021186 transducin beta-like 1X isoform a [Homo sapiens] 86 3e-17
gi|5032159 transducin beta-like 1X isoform a [Homo sapiens] 86 3e-17
gi|13376840 WD repeat domain 61 [Homo sapiens] 84 6e-17
gi|61743926 F-box and WD repeat domain containing 7 isoform 3 [H... 84 1e-16
gi|16117781 F-box and WD repeat domain containing 7 isoform 1 [H... 84 1e-16
gi|16117779 F-box and WD repeat domain containing 7 isoform 2 [H... 84 1e-16
gi|115298668 WD repeat domain 57 (U5 snRNP specific) [Homo sapiens] 82 2e-16
gi|4505895 pleiotropic regulator 1 (PRL1 homolog, Arabidopsis) [... 82 2e-16
gi|19913367 transducin beta-like 1Y [Homo sapiens] 82 2e-16
>gi|62234438 Notchless gene homolog isoform b [Homo sapiens]
Length = 193
Score = 388 bits (997), Expect = e-108
Identities = 193/193 (100%), Positives = 193/193 (100%)
Query: 1 MALSTDYALRTGAFEPAEASVNPQDLQGSLQELKERALSRYNLVRGQGPERLVSGSDDFT 60
MALSTDYALRTGAFEPAEASVNPQDLQGSLQELKERALSRYNLVRGQGPERLVSGSDDFT
Sbjct: 1 MALSTDYALRTGAFEPAEASVNPQDLQGSLQELKERALSRYNLVRGQGPERLVSGSDDFT 60
Query: 61 LFLWSPAEDKKPLTRMTGHQALINQVLFSPDSRIVASASFDKSIKLWDGRTGKYLASLRG 120
LFLWSPAEDKKPLTRMTGHQALINQVLFSPDSRIVASASFDKSIKLWDGRTGKYLASLRG
Sbjct: 61 LFLWSPAEDKKPLTRMTGHQALINQVLFSPDSRIVASASFDKSIKLWDGRTGKYLASLRG 120
Query: 121 HVAAVYQIAWSADSRLLVSGSSDSTLKVWDVKAQKLAMDLPGHADEVYAVDWSPDGQRVA 180
HVAAVYQIAWSADSRLLVSGSSDSTLKVWDVKAQKLAMDLPGHADEVYAVDWSPDGQRVA
Sbjct: 121 HVAAVYQIAWSADSRLLVSGSSDSTLKVWDVKAQKLAMDLPGHADEVYAVDWSPDGQRVA 180
Query: 181 SGGKDKCLRIWRR 193
SGGKDKCLRIWRR
Sbjct: 181 SGGKDKCLRIWRR 193
>gi|62234461 Notchless gene homolog isoform a [Homo sapiens]
Length = 485
Score = 388 bits (997), Expect = e-108
Identities = 193/193 (100%), Positives = 193/193 (100%)
Query: 1 MALSTDYALRTGAFEPAEASVNPQDLQGSLQELKERALSRYNLVRGQGPERLVSGSDDFT 60
MALSTDYALRTGAFEPAEASVNPQDLQGSLQELKERALSRYNLVRGQGPERLVSGSDDFT
Sbjct: 293 MALSTDYALRTGAFEPAEASVNPQDLQGSLQELKERALSRYNLVRGQGPERLVSGSDDFT 352
Query: 61 LFLWSPAEDKKPLTRMTGHQALINQVLFSPDSRIVASASFDKSIKLWDGRTGKYLASLRG 120
LFLWSPAEDKKPLTRMTGHQALINQVLFSPDSRIVASASFDKSIKLWDGRTGKYLASLRG
Sbjct: 353 LFLWSPAEDKKPLTRMTGHQALINQVLFSPDSRIVASASFDKSIKLWDGRTGKYLASLRG 412
Query: 121 HVAAVYQIAWSADSRLLVSGSSDSTLKVWDVKAQKLAMDLPGHADEVYAVDWSPDGQRVA 180
HVAAVYQIAWSADSRLLVSGSSDSTLKVWDVKAQKLAMDLPGHADEVYAVDWSPDGQRVA
Sbjct: 413 HVAAVYQIAWSADSRLLVSGSSDSTLKVWDVKAQKLAMDLPGHADEVYAVDWSPDGQRVA 472
Query: 181 SGGKDKCLRIWRR 193
SGGKDKCLRIWRR
Sbjct: 473 SGGKDKCLRIWRR 485
Score = 77.8 bits (190), Expect = 5e-15
Identities = 45/147 (30%), Positives = 74/147 (50%), Gaps = 8/147 (5%)
Query: 52 LVSGSDDFTLFLWSPAEDKKPLTRMTGHQALINQVLFSPDSRIVASASFDKSIKLWDGRT 111
L SGS D T+ W + + T GH+ + + +SPD R +AS + I LWD T
Sbjct: 129 LASGSGDTTVRFWDLSTETPHFT-CKGHRHWVLSISWSPDGRKLASGCKNGQILLWDPST 187
Query: 112 GKYLA-SLRGHVAAVYQIAW-----SADSRLLVSGSSDSTLKVWDVKAQKLAMDLPGHAD 165
GK + +L GH + ++W + + R + S S D ++++WD A + L GH
Sbjct: 188 GKQVGRTLAGHSKWITGLSWEPLHANPECRYVASSSKDGSVRIWDTTAGRCERILTGHTQ 247
Query: 166 EVYAVDWSPDGQRVASGGKDKCLRIWR 192
V + W DG + S +D+ +++WR
Sbjct: 248 SVTCLRWGGDG-LLYSASQDRTIKVWR 273
Score = 72.4 bits (176), Expect = 2e-13
Identities = 40/122 (32%), Positives = 61/122 (50%), Gaps = 6/122 (4%)
Query: 76 MTGHQALINQVLFSPDSRIVASASFDKSIKLWDGRTGKYLASLRGHVAAVYQIAWSADSR 135
+ GH + V FSP + +AS S D +++ WD T + +GH V I+WS D R
Sbjct: 110 LEGHSEAVISVAFSPTGKYLASGSGDTTVRFWDLSTETPHFTCKGHRHWVLSISWSPDGR 169
Query: 136 LLVSGSSDSTLKVWDVKAQK-LAMDLPGHADEVYAVDW-----SPDGQRVASGGKDKCLR 189
L SG + + +WD K + L GH+ + + W +P+ + VAS KD +R
Sbjct: 170 KLASGCKNGQILLWDPSTGKQVGRTLAGHSKWITGLSWEPLHANPECRYVASSSKDGSVR 229
Query: 190 IW 191
IW
Sbjct: 230 IW 231
Score = 70.1 bits (170), Expect = 1e-12
Identities = 43/130 (33%), Positives = 62/130 (47%), Gaps = 6/130 (4%)
Query: 51 RLVSGSDDFTLFLWSPAEDKKPLTRMTGHQALINQVLF-----SPDSRIVASASFDKSIK 105
+L SG + + LW P+ K+ + GH I + + +P+ R VAS+S D S++
Sbjct: 170 KLASGCKNGQILLWDPSTGKQVGRTLAGHSKWITGLSWEPLHANPECRYVASSSKDGSVR 229
Query: 106 LWDGRTGKYLASLRGHVAAVYQIAWSADSRLLVSGSSDSTLKVWDVKAQKLAMDLPGHAD 165
+WD G+ L GH +V + W D LL S S D T+KVW L L GH
Sbjct: 230 IWDTTAGRCERILTGHTQSVTCLRWGGDG-LLYSASQDRTIKVWRAHDGVLCRTLQGHGH 288
Query: 166 EVYAVDWSPD 175
V + S D
Sbjct: 289 WVNTMALSTD 298
Score = 66.2 bits (160), Expect = 2e-11
Identities = 29/76 (38%), Positives = 46/76 (60%)
Query: 116 ASLRGHVAAVYQIAWSADSRLLVSGSSDSTLKVWDVKAQKLAMDLPGHADEVYAVDWSPD 175
+SL GH AV +A+S + L SGS D+T++ WD+ + GH V ++ WSPD
Sbjct: 108 SSLEGHSEAVISVAFSPTGKYLASGSGDTTVRFWDLSTETPHFTCKGHRHWVLSISWSPD 167
Query: 176 GQRVASGGKDKCLRIW 191
G+++ASG K+ + +W
Sbjct: 168 GRKLASGCKNGQILLW 183
Score = 49.3 bits (116), Expect = 2e-06
Identities = 46/183 (25%), Positives = 72/183 (39%), Gaps = 45/183 (24%)
Query: 52 LVSGSDDFTLFLWSPAEDKKPLTRMTGHQALINQVLFSPDSRIVASASFDKSIKLWDGRT 111
+ S S D ++ +W + +TGH + + + D ++ SAS D++IK+W
Sbjct: 219 VASSSKDGSVRIWDTTAGRCERI-LTGHTQSVTCLRWGGDG-LLYSASQDRTIKVWRAHD 276
Query: 112 GKYLASLRGHVAAVYQIAWSADSRL----------------------------------- 136
G +L+GH V +A S D L
Sbjct: 277 GVLCRTLQGHGHWVNTMALSTDYALRTGAFEPAEASVNPQDLQGSLQELKERALSRYNLV 336
Query: 137 -------LVSGSSDSTLKVWDVKAQKLAMD-LPGHADEVYAVDWSPDGQRVASGGKDKCL 188
LVSGS D TL +W K + + GH + V +SPD + VAS DK +
Sbjct: 337 RGQGPERLVSGSDDFTLFLWSPAEDKKPLTRMTGHQALINQVLFSPDSRIVASASFDKSI 396
Query: 189 RIW 191
++W
Sbjct: 397 KLW 399
>gi|16554629 WD repeat domain 5 [Homo sapiens]
Length = 334
Score = 105 bits (262), Expect = 2e-23
Identities = 47/116 (40%), Positives = 71/116 (61%)
Query: 76 MTGHQALINQVLFSPDSRIVASASFDKSIKLWDGRTGKYLASLRGHVAAVYQIAWSADSR 135
+ GH ++ V FSP+ +AS+S DK IK+W GK+ ++ GH + +AWS+DS
Sbjct: 41 LAGHTKAVSSVKFSPNGEWLASSSADKLIKIWGAYDGKFEKTISGHKLGISDVAWSSDSN 100
Query: 136 LLVSGSSDSTLKVWDVKAQKLAMDLPGHADEVYAVDWSPDGQRVASGGKDKCLRIW 191
LLVS S D TLK+WDV + K L GH++ V+ +++P + SG D+ +RIW
Sbjct: 101 LLVSASDDKTLKIWDVSSGKCLKTLKGHSNYVFCCNFNPQSNLIVSGSFDESVRIW 156
Score = 105 bits (261), Expect = 3e-23
Identities = 56/142 (39%), Positives = 84/142 (59%), Gaps = 1/142 (0%)
Query: 50 ERLVSGSDDFTLFLWSPAEDKKPLTRMTGHQALINQVLFSPDSRIVASASFDKSIKLWDG 109
E L S S D + +W + K T ++GH+ I+ V +S DS ++ SAS DK++K+WD
Sbjct: 58 EWLASSSADKLIKIWGAYDGKFEKT-ISGHKLGISDVAWSSDSNLLVSASDDKTLKIWDV 116
Query: 110 RTGKYLASLRGHVAAVYQIAWSADSRLLVSGSSDSTLKVWDVKAQKLAMDLPGHADEVYA 169
+GK L +L+GH V+ ++ S L+VSGS D ++++WDVK K LP H+D V A
Sbjct: 117 SSGKCLKTLKGHSNYVFCCNFNPQSNLIVSGSFDESVRIWDVKTGKCLKTLPAHSDPVSA 176
Query: 170 VDWSPDGQRVASGGKDKCLRIW 191
V ++ DG + S D RIW
Sbjct: 177 VHFNRDGSLIVSSSYDGLCRIW 198
Score = 85.5 bits (210), Expect = 3e-17
Identities = 48/141 (34%), Positives = 75/141 (53%), Gaps = 2/141 (1%)
Query: 52 LVSGSDDFTLFLWSPAEDKKPLTRMTGHQALINQVLFSPDSRIVASASFDKSIKLWDGRT 111
LVS SDD TL +W + K L + GH + F+P S ++ S SFD+S+++WD +T
Sbjct: 102 LVSASDDKTLKIWDVSSGKC-LKTLKGHSNYVFCCNFNPQSNLIVSGSFDESVRIWDVKT 160
Query: 112 GKYLASLRGHVAAVYQIAWSADSRLLVSGSSDSTLKVWD-VKAQKLAMDLPGHADEVYAV 170
GK L +L H V + ++ D L+VS S D ++WD Q L + V V
Sbjct: 161 GKCLKTLPAHSDPVSAVHFNRDGSLIVSSSYDGLCRIWDTASGQCLKTLIDDDNPPVSFV 220
Query: 171 DWSPDGQRVASGGKDKCLRIW 191
+SP+G+ + + D L++W
Sbjct: 221 KFSPNGKYILAATLDNTLKLW 241
Score = 71.6 bits (174), Expect = 4e-13
Identities = 41/146 (28%), Positives = 73/146 (50%), Gaps = 5/146 (3%)
Query: 52 LVSGSDDFTLFLWSPAEDKKPLTRMTGHQALINQVLFSPDSRIVASASFDKSIKLWDGRT 111
+VS S D +W A + T + ++ V FSP+ + + +A+ D ++KLWD
Sbjct: 186 IVSSSYDGLCRIWDTASGQCLKTLIDDDNPPVSFVKFSPNGKYILAATLDNTLKLWDYSK 245
Query: 112 GKYLASLRGHVAAVYQIAWS---ADSRLLVSGSSDSTLKVWDVKAQKLAMDLPGHADEVY 168
GK L + GH Y I + + +VSGS D+ + +W+++ +++ L GH D V
Sbjct: 246 GKCLKTYTGHKNEKYCIFANFSVTGGKWIVSGSEDNLVYIWNLQTKEIVQKLQGHTDVVI 305
Query: 169 AVDWSPDGQRVASGG--KDKCLRIWR 192
+ P +AS DK +++W+
Sbjct: 306 STACHPTENIIASAALENDKTIKLWK 331
Score = 52.4 bits (124), Expect = 2e-07
Identities = 25/75 (33%), Positives = 36/75 (48%)
Query: 117 SLRGHVAAVYQIAWSADSRLLVSGSSDSTLKVWDVKAQKLAMDLPGHADEVYAVDWSPDG 176
+L GH AV + +S + L S S+D +K+W K + GH + V WS D
Sbjct: 40 TLAGHTKAVSSVKFSPNGEWLASSSADKLIKIWGAYDGKFEKTISGHKLGISDVAWSSDS 99
Query: 177 QRVASGGKDKCLRIW 191
+ S DK L+IW
Sbjct: 100 NLLVSASDDKTLKIW 114
Score = 41.2 bits (95), Expect = 6e-04
Identities = 21/62 (33%), Positives = 38/62 (61%), Gaps = 3/62 (4%)
Query: 48 GPERLVSGSDDFTLFLWSPAEDKKPLTRMTGHQALINQVLFSPDSRIVASASF--DKSIK 105
G + +VSGS+D +++W+ + K+ + ++ GH ++ P I+ASA+ DK+IK
Sbjct: 270 GGKWIVSGSEDNLVYIWN-LQTKEIVQKLQGHTDVVISTACHPTENIIASAALENDKTIK 328
Query: 106 LW 107
LW
Sbjct: 329 LW 330
Score = 34.7 bits (78), Expect = 0.052
Identities = 15/36 (41%), Positives = 22/36 (61%)
Query: 156 LAMDLPGHADEVYAVDWSPDGQRVASGGKDKCLRIW 191
L L GH V +V +SP+G+ +AS DK ++IW
Sbjct: 37 LKFTLAGHTKAVSSVKFSPNGEWLASSSADKLIKIW 72
>gi|16554627 WD repeat domain 5 [Homo sapiens]
Length = 334
Score = 105 bits (262), Expect = 2e-23
Identities = 47/116 (40%), Positives = 71/116 (61%)
Query: 76 MTGHQALINQVLFSPDSRIVASASFDKSIKLWDGRTGKYLASLRGHVAAVYQIAWSADSR 135
+ GH ++ V FSP+ +AS+S DK IK+W GK+ ++ GH + +AWS+DS
Sbjct: 41 LAGHTKAVSSVKFSPNGEWLASSSADKLIKIWGAYDGKFEKTISGHKLGISDVAWSSDSN 100
Query: 136 LLVSGSSDSTLKVWDVKAQKLAMDLPGHADEVYAVDWSPDGQRVASGGKDKCLRIW 191
LLVS S D TLK+WDV + K L GH++ V+ +++P + SG D+ +RIW
Sbjct: 101 LLVSASDDKTLKIWDVSSGKCLKTLKGHSNYVFCCNFNPQSNLIVSGSFDESVRIW 156
Score = 105 bits (261), Expect = 3e-23
Identities = 56/142 (39%), Positives = 84/142 (59%), Gaps = 1/142 (0%)
Query: 50 ERLVSGSDDFTLFLWSPAEDKKPLTRMTGHQALINQVLFSPDSRIVASASFDKSIKLWDG 109
E L S S D + +W + K T ++GH+ I+ V +S DS ++ SAS DK++K+WD
Sbjct: 58 EWLASSSADKLIKIWGAYDGKFEKT-ISGHKLGISDVAWSSDSNLLVSASDDKTLKIWDV 116
Query: 110 RTGKYLASLRGHVAAVYQIAWSADSRLLVSGSSDSTLKVWDVKAQKLAMDLPGHADEVYA 169
+GK L +L+GH V+ ++ S L+VSGS D ++++WDVK K LP H+D V A
Sbjct: 117 SSGKCLKTLKGHSNYVFCCNFNPQSNLIVSGSFDESVRIWDVKTGKCLKTLPAHSDPVSA 176
Query: 170 VDWSPDGQRVASGGKDKCLRIW 191
V ++ DG + S D RIW
Sbjct: 177 VHFNRDGSLIVSSSYDGLCRIW 198
Score = 85.5 bits (210), Expect = 3e-17
Identities = 48/141 (34%), Positives = 75/141 (53%), Gaps = 2/141 (1%)
Query: 52 LVSGSDDFTLFLWSPAEDKKPLTRMTGHQALINQVLFSPDSRIVASASFDKSIKLWDGRT 111
LVS SDD TL +W + K L + GH + F+P S ++ S SFD+S+++WD +T
Sbjct: 102 LVSASDDKTLKIWDVSSGKC-LKTLKGHSNYVFCCNFNPQSNLIVSGSFDESVRIWDVKT 160
Query: 112 GKYLASLRGHVAAVYQIAWSADSRLLVSGSSDSTLKVWD-VKAQKLAMDLPGHADEVYAV 170
GK L +L H V + ++ D L+VS S D ++WD Q L + V V
Sbjct: 161 GKCLKTLPAHSDPVSAVHFNRDGSLIVSSSYDGLCRIWDTASGQCLKTLIDDDNPPVSFV 220
Query: 171 DWSPDGQRVASGGKDKCLRIW 191
+SP+G+ + + D L++W
Sbjct: 221 KFSPNGKYILAATLDNTLKLW 241
Score = 71.6 bits (174), Expect = 4e-13
Identities = 41/146 (28%), Positives = 73/146 (50%), Gaps = 5/146 (3%)
Query: 52 LVSGSDDFTLFLWSPAEDKKPLTRMTGHQALINQVLFSPDSRIVASASFDKSIKLWDGRT 111
+VS S D +W A + T + ++ V FSP+ + + +A+ D ++KLWD
Sbjct: 186 IVSSSYDGLCRIWDTASGQCLKTLIDDDNPPVSFVKFSPNGKYILAATLDNTLKLWDYSK 245
Query: 112 GKYLASLRGHVAAVYQIAWS---ADSRLLVSGSSDSTLKVWDVKAQKLAMDLPGHADEVY 168
GK L + GH Y I + + +VSGS D+ + +W+++ +++ L GH D V
Sbjct: 246 GKCLKTYTGHKNEKYCIFANFSVTGGKWIVSGSEDNLVYIWNLQTKEIVQKLQGHTDVVI 305
Query: 169 AVDWSPDGQRVASGG--KDKCLRIWR 192
+ P +AS DK +++W+
Sbjct: 306 STACHPTENIIASAALENDKTIKLWK 331
Score = 52.4 bits (124), Expect = 2e-07
Identities = 25/75 (33%), Positives = 36/75 (48%)
Query: 117 SLRGHVAAVYQIAWSADSRLLVSGSSDSTLKVWDVKAQKLAMDLPGHADEVYAVDWSPDG 176
+L GH AV + +S + L S S+D +K+W K + GH + V WS D
Sbjct: 40 TLAGHTKAVSSVKFSPNGEWLASSSADKLIKIWGAYDGKFEKTISGHKLGISDVAWSSDS 99
Query: 177 QRVASGGKDKCLRIW 191
+ S DK L+IW
Sbjct: 100 NLLVSASDDKTLKIW 114
Score = 41.2 bits (95), Expect = 6e-04
Identities = 21/62 (33%), Positives = 38/62 (61%), Gaps = 3/62 (4%)
Query: 48 GPERLVSGSDDFTLFLWSPAEDKKPLTRMTGHQALINQVLFSPDSRIVASASF--DKSIK 105
G + +VSGS+D +++W+ + K+ + ++ GH ++ P I+ASA+ DK+IK
Sbjct: 270 GGKWIVSGSEDNLVYIWN-LQTKEIVQKLQGHTDVVISTACHPTENIIASAALENDKTIK 328
Query: 106 LW 107
LW
Sbjct: 329 LW 330
Score = 34.7 bits (78), Expect = 0.052
Identities = 15/36 (41%), Positives = 22/36 (61%)
Query: 156 LAMDLPGHADEVYAVDWSPDGQRVASGGKDKCLRIW 191
L L GH V +V +SP+G+ +AS DK ++IW
Sbjct: 37 LKFTLAGHTKAVSSVKFSPNGEWLASSSADKLIKIW 72
>gi|23199987 WD repeat domain 5B [Homo sapiens]
Length = 330
Score = 103 bits (257), Expect = 9e-23
Identities = 57/142 (40%), Positives = 81/142 (57%), Gaps = 1/142 (0%)
Query: 50 ERLVSGSDDFTLFLWSPAEDKKPLTRMTGHQALINQVLFSPDSRIVASASFDKSIKLWDG 109
E L S S D + +W + K T + GH I+ V +S DS + SAS DK++KLWD
Sbjct: 54 EWLASSSADRLIIIWGAYDGKYEKT-LYGHNLEISDVAWSSDSSRLVSASDDKTLKLWDV 112
Query: 110 RTGKYLASLRGHVAAVYQIAWSADSRLLVSGSSDSTLKVWDVKAQKLAMDLPGHADEVYA 169
R+GK L +L+GH V+ ++ S L++SGS D T+K+W+VK K L H+D V A
Sbjct: 113 RSGKCLKTLKGHSNYVFCCNFNPPSNLIISGSFDETVKIWEVKTGKCLKTLSAHSDPVSA 172
Query: 170 VDWSPDGQRVASGGKDKCLRIW 191
V ++ G + SG D RIW
Sbjct: 173 VHFNCSGSLIVSGSYDGLCRIW 194
Score = 97.8 bits (242), Expect = 5e-21
Identities = 45/116 (38%), Positives = 70/116 (60%)
Query: 76 MTGHQALINQVLFSPDSRIVASASFDKSIKLWDGRTGKYLASLRGHVAAVYQIAWSADSR 135
+ GH ++ V FSP+ +AS+S D+ I +W GKY +L GH + +AWS+DS
Sbjct: 37 LVGHTEAVSSVKFSPNGEWLASSSADRLIIIWGAYDGKYEKTLYGHNLEISDVAWSSDSS 96
Query: 136 LLVSGSSDSTLKVWDVKAQKLAMDLPGHADEVYAVDWSPDGQRVASGGKDKCLRIW 191
LVS S D TLK+WDV++ K L GH++ V+ +++P + SG D+ ++IW
Sbjct: 97 RLVSASDDKTLKLWDVRSGKCLKTLKGHSNYVFCCNFNPPSNLIISGSFDETVKIW 152
Score = 86.3 bits (212), Expect = 1e-17
Identities = 49/142 (34%), Positives = 75/142 (52%), Gaps = 2/142 (1%)
Query: 51 RLVSGSDDFTLFLWSPAEDKKPLTRMTGHQALINQVLFSPDSRIVASASFDKSIKLWDGR 110
RLVS SDD TL LW K L + GH + F+P S ++ S SFD+++K+W+ +
Sbjct: 97 RLVSASDDKTLKLWD-VRSGKCLKTLKGHSNYVFCCNFNPPSNLIISGSFDETVKIWEVK 155
Query: 111 TGKYLASLRGHVAAVYQIAWSADSRLLVSGSSDSTLKVWD-VKAQKLAMDLPGHADEVYA 169
TGK L +L H V + ++ L+VSGS D ++WD Q L + V
Sbjct: 156 TGKCLKTLSAHSDPVSAVHFNCSGSLIVSGSYDGLCRIWDAASGQCLKTLVDDDNPPVSF 215
Query: 170 VDWSPDGQRVASGGKDKCLRIW 191
V +SP+G+ + + D L++W
Sbjct: 216 VKFSPNGKYILTATLDNTLKLW 237
Score = 72.4 bits (176), Expect = 2e-13
Identities = 41/145 (28%), Positives = 73/145 (50%), Gaps = 5/145 (3%)
Query: 52 LVSGSDDFTLFLWSPAEDKKPLTRMTGHQALINQVLFSPDSRIVASASFDKSIKLWDGRT 111
+VSGS D +W A + T + ++ V FSP+ + + +A+ D ++KLWD
Sbjct: 182 IVSGSYDGLCRIWDAASGQCLKTLVDDDNPPVSFVKFSPNGKYILTATLDNTLKLWDYSR 241
Query: 112 GKYLASLRGHVAAVYQIAWS---ADSRLLVSGSSDSTLKVWDVKAQKLAMDLPGHADEVY 168
G+ L + GH Y I + + +VSGS D+ + +W+++ +++ L GH D V
Sbjct: 242 GRCLKTYTGHKNEKYCIFANFSVTGGKWIVSGSEDNLVYIWNLQTKEIVQKLQGHTDVVI 301
Query: 169 AVDWSPDGQRVASGG--KDKCLRIW 191
+ P +AS DK +++W
Sbjct: 302 SAACHPTENLIASAALENDKTIKLW 326
Score = 53.5 bits (127), Expect = 1e-07
Identities = 29/100 (29%), Positives = 49/100 (49%)
Query: 92 SRIVASASFDKSIKLWDGRTGKYLASLRGHVAAVYQIAWSADSRLLVSGSSDSTLKVWDV 151
+++ S+S ++S ++ + +L GH AV + +S + L S S+D + +W
Sbjct: 11 AQLALSSSANQSKEVPENPNYALKCTLVGHTEAVSSVKFSPNGEWLASSSADRLIIIWGA 70
Query: 152 KAQKLAMDLPGHADEVYAVDWSPDGQRVASGGKDKCLRIW 191
K L GH E+ V WS D R+ S DK L++W
Sbjct: 71 YDGKYEKTLYGHNLEISDVAWSSDSSRLVSASDDKTLKLW 110
Score = 40.4 bits (93), Expect = 0.001
Identities = 20/62 (32%), Positives = 38/62 (61%), Gaps = 3/62 (4%)
Query: 48 GPERLVSGSDDFTLFLWSPAEDKKPLTRMTGHQALINQVLFSPDSRIVASASF--DKSIK 105
G + +VSGS+D +++W+ + K+ + ++ GH ++ P ++ASA+ DK+IK
Sbjct: 266 GGKWIVSGSEDNLVYIWN-LQTKEIVQKLQGHTDVVISAACHPTENLIASAALENDKTIK 324
Query: 106 LW 107
LW
Sbjct: 325 LW 326
Score = 37.0 bits (84), Expect = 0.010
Identities = 19/60 (31%), Positives = 35/60 (58%)
Query: 132 ADSRLLVSGSSDSTLKVWDVKAQKLAMDLPGHADEVYAVDWSPDGQRVASGGKDKCLRIW 191
A ++L +S S++ + +V + L L GH + V +V +SP+G+ +AS D+ + IW
Sbjct: 9 AKAQLALSSSANQSKEVPENPNYALKCTLVGHTEAVSSVKFSPNGEWLASSSADRLIIIW 68
>gi|83779014 katanin p80 subunit B 1 [Homo sapiens]
Length = 655
Score = 97.1 bits (240), Expect = 8e-21
Identities = 57/149 (38%), Positives = 81/149 (54%), Gaps = 2/149 (1%)
Query: 44 VRGQGPERL-VSGSDDFTLFLWSPAEDKKPLTRMTGHQALINQVLFSPDSRIVASASFDK 102
VR PE L V+GS ++ +W E K L + GH+A I + F P VAS S D
Sbjct: 69 VRLNTPEELIVAGSQSGSIRVWD-LEAAKILRTLMGHKANICSLDFHPYGEFVASGSQDT 127
Query: 103 SIKLWDGRTGKYLASLRGHVAAVYQIAWSADSRLLVSGSSDSTLKVWDVKAQKLAMDLPG 162
+IKLWD R + RGH AV + +S D + L S + D T+K+WD+ A K+ + PG
Sbjct: 128 NIKLWDIRRKGCVFRYRGHSQAVRCLRFSPDGKWLASAADDHTVKLWDLTAGKMMSEFPG 187
Query: 163 HADEVYAVDWSPDGQRVASGGKDKCLRIW 191
H V V++ P+ +ASG D+ +R W
Sbjct: 188 HTGPVNVVEFHPNEYLLASGSSDRTIRFW 216
Score = 88.2 bits (217), Expect = 4e-18
Identities = 50/165 (30%), Positives = 86/165 (52%), Gaps = 6/165 (3%)
Query: 30 LQELKERALSRYNLVRGQGPERLVS-GSDDFTLFLWSPAEDKKP--LTRMTGHQALINQV 86
LQE+ A + +LV G+ RL++ G DD + LWS KP + +TGH + + V
Sbjct: 13 LQEIVAHASNVSSLVLGKASGRLLATGGDDCRVNLWSI---NKPNCIMSLTGHTSPVESV 69
Query: 87 LFSPDSRIVASASFDKSIKLWDGRTGKYLASLRGHVAAVYQIAWSADSRLLVSGSSDSTL 146
+ ++ + S SI++WD K L +L GH A + + + + SGS D+ +
Sbjct: 70 RLNTPEELIVAGSQSGSIRVWDLEAAKILRTLMGHKANICSLDFHPYGEFVASGSQDTNI 129
Query: 147 KVWDVKAQKLAMDLPGHADEVYAVDWSPDGQRVASGGKDKCLRIW 191
K+WD++ + GH+ V + +SPDG+ +AS D +++W
Sbjct: 130 KLWDIRRKGCVFRYRGHSQAVRCLRFSPDGKWLASAADDHTVKLW 174
Score = 85.1 bits (209), Expect = 3e-17
Identities = 49/142 (34%), Positives = 78/142 (54%), Gaps = 2/142 (1%)
Query: 50 ERLVSGSDDFTLFLWSPAEDKKPLTRMTGHQALINQVLFSPDSRIVASASFDKSIKLWDG 109
E + SGS D + LW K + R GH + + FSPD + +ASA+ D ++KLWD
Sbjct: 118 EFVASGSQDTNIKLWD-IRRKGCVFRYRGHSQAVRCLRFSPDGKWLASAADDHTVKLWDL 176
Query: 110 RTGKYLASLRGHVAAVYQIAWSADSRLLVSGSSDSTLKVWDVKAQKLAMDLPGHADEVYA 169
GK ++ GH V + + + LL SGSSD T++ WD++ ++ + G V +
Sbjct: 177 TAGKMMSEFPGHTGPVNVVEFHPNEYLLASGSSDRTIRFWDLEKFQVVSCIEGEPGPVRS 236
Query: 170 VDWSPDGQRVASGGKDKCLRIW 191
V ++PDG + SG +D LR++
Sbjct: 237 VLFNPDGCCLYSGCQDS-LRVY 257
>gi|7657439 PCAF associated factor 65 beta isoform a [Homo sapiens]
Length = 589
Score = 95.5 bits (236), Expect = 2e-20
Identities = 49/138 (35%), Positives = 75/138 (54%), Gaps = 1/138 (0%)
Query: 54 SGSDDFTLFLWSPAEDKKPLTRMTGHQALINQVLFSPDSRIVASASFDKSIKLWDGRTGK 113
SGS D T LWS + PL GH A ++ V F P+S +A+ S DK+++LW + G
Sbjct: 401 SGSHDRTARLWS-FDRTYPLRIYAGHLADVDCVKFHPNSNYLATGSTDKTVRLWSAQQGN 459
Query: 114 YLASLRGHVAAVYQIAWSADSRLLVSGSSDSTLKVWDVKAQKLAMDLPGHADEVYAVDWS 173
+ GH V +A+S + + L S D LK+WD+ + L +L GH D + ++ +S
Sbjct: 460 SVRLFTGHRGPVLSLAFSPNGKYLASAGEDQRLKLWDLASGTLYKELRGHTDNITSLTFS 519
Query: 174 PDGQRVASGGKDKCLRIW 191
PD +AS D +R+W
Sbjct: 520 PDSGLIASASMDNSVRVW 537
Score = 80.1 bits (196), Expect = 1e-15
Identities = 41/119 (34%), Positives = 67/119 (56%), Gaps = 1/119 (0%)
Query: 52 LVSGSDDFTLFLWSPAEDKKPLTRMTGHQALINQVLFSPDSRIVASASFDKSIKLWDGRT 111
L +GS D T+ LWS A+ + TGH+ + + FSP+ + +ASA D+ +KLWD +
Sbjct: 441 LATGSTDKTVRLWS-AQQGNSVRLFTGHRGPVLSLAFSPNGKYLASAGEDQRLKLWDLAS 499
Query: 112 GKYLASLRGHVAAVYQIAWSADSRLLVSGSSDSTLKVWDVKAQKLAMDLPGHADEVYAV 170
G LRGH + + +S DS L+ S S D++++VWD++ + G + E+ V
Sbjct: 500 GTLYKELRGHTDNITSLTFSPDSGLIASASMDNSVRVWDIRNTYCSAPADGSSSELVGV 558
Score = 67.4 bits (163), Expect = 7e-12
Identities = 40/140 (28%), Positives = 70/140 (50%), Gaps = 1/140 (0%)
Query: 52 LVSGSDDFTLFLWSPAEDKKPLTRMTGHQALINQVLFSPDSRIVASASFDKSIKLWDGRT 111
L+S S+D ++ W + GH + + SP S AS S D++ +LW
Sbjct: 357 LLSCSEDMSIRYWDLGSFTNTVLYQ-GHAYPVWDLDISPYSLYFASGSHDRTARLWSFDR 415
Query: 112 GKYLASLRGHVAAVYQIAWSADSRLLVSGSSDSTLKVWDVKAQKLAMDLPGHADEVYAVD 171
L GH+A V + + +S L +GS+D T+++W + GH V ++
Sbjct: 416 TYPLRIYAGHLADVDCVKFHPNSNYLATGSTDKTVRLWSAQQGNSVRLFTGHRGPVLSLA 475
Query: 172 WSPDGQRVASGGKDKCLRIW 191
+SP+G+ +AS G+D+ L++W
Sbjct: 476 FSPNGKYLASAGEDQRLKLW 495
Score = 61.2 bits (147), Expect = 5e-10
Identities = 41/144 (28%), Positives = 61/144 (42%), Gaps = 32/144 (22%)
Query: 80 QALINQVLFSPDSRIVASASFDKSIKLW-------------------------------- 107
+ L+N SPDS+++A+ + IKLW
Sbjct: 268 EQLLNTAEISPDSKLLAAGFDNSCIKLWSLRSKKLKSEPHQVDVSRIHLACDILEEEDDE 327
Query: 108 DGRTGKYLASLRGHVAAVYQIAWSADSRLLVSGSSDSTLKVWDVKAQKLAMDLPGHADEV 167
D G + LRGH VY + ADS L+S S D +++ WD+ + + GHA V
Sbjct: 328 DDNAGTEMKILRGHCGPVYSTRFLADSSGLLSCSEDMSIRYWDLGSFTNTVLYQGHAYPV 387
Query: 168 YAVDWSPDGQRVASGGKDKCLRIW 191
+ +D SP ASG D+ R+W
Sbjct: 388 WDLDISPYSLYFASGSHDRTARLW 411
>gi|113865883 WD repeat domain 38 [Homo sapiens]
Length = 314
Score = 95.1 bits (235), Expect = 3e-20
Identities = 50/142 (35%), Positives = 80/142 (56%), Gaps = 1/142 (0%)
Query: 50 ERLVSGSDDFTLFLWSPAEDKKPLTRMTGHQALINQVLFSPDSRIVASASFDKSIKLWDG 109
+ L++GS+D ++ W + L R+ GH + FSPD + ASAS D +++LWD
Sbjct: 34 QMLLTGSEDGCVYGWETRSGQL-LWRLGGHTGPVKFCRFSPDGHLFASASCDCTVRLWDV 92
Query: 110 RTGKYLASLRGHVAAVYQIAWSADSRLLVSGSSDSTLKVWDVKAQKLAMDLPGHADEVYA 169
K L L+GH +V +++S DSR L SG D + +WDV++ ++ L GH D + +
Sbjct: 93 ARAKCLRVLKGHQRSVETVSFSPDSRQLASGGWDKRVMLWDVQSGQMLRLLVGHRDSIQS 152
Query: 170 VDWSPDGQRVASGGKDKCLRIW 191
D+SP +A+G D + IW
Sbjct: 153 SDFSPTVNCLATGSWDSTVHIW 174
Score = 86.7 bits (213), Expect = 1e-17
Identities = 53/142 (37%), Positives = 78/142 (54%), Gaps = 5/142 (3%)
Query: 54 SGSDDFTLFLWSPAEDKKPLTRMTGHQALINQVLFSPDSRIVASASFDKSIKLWDGRTGK 113
S S D T+ LW A K L + GHQ + V FSPDSR +AS +DK + LWD ++G+
Sbjct: 80 SASCDCTVRLWDVAR-AKCLRVLKGHQRSVETVSFSPDSRQLASGGWDKRVMLWDVQSGQ 138
Query: 114 YLASLRGHVAAVYQIAWSADSRLLVSGSSDSTLKVWDVKAQKLAMD---LPGHADEVYAV 170
L L GH ++ +S L +GS DST+ +WD++ A+ L GH+ + +
Sbjct: 139 MLRLLVGHRDSIQSSDFSPTVNCLATGSWDSTVHIWDLRMVTPAVSHQALEGHSANISCL 198
Query: 171 DWSPDGQRVASGGKDKCLRIWR 192
+S G +ASG DK + IW+
Sbjct: 199 CYSASG-LLASGSWDKTIHIWK 219
Score = 82.4 bits (202), Expect = 2e-16
Identities = 42/113 (37%), Positives = 61/113 (53%)
Query: 79 HQALINQVLFSPDSRIVASASFDKSIKLWDGRTGKYLASLRGHVAAVYQIAWSADSRLLV 138
H +N FSPD +++ + S D + W+ R+G+ L L GH V +S D L
Sbjct: 20 HGGEVNSSAFSPDGQMLLTGSEDGCVYGWETRSGQLLWRLGGHTGPVKFCRFSPDGHLFA 79
Query: 139 SGSSDSTLKVWDVKAQKLAMDLPGHADEVYAVDWSPDGQRVASGGKDKCLRIW 191
S S D T+++WDV K L GH V V +SPD +++ASGG DK + +W
Sbjct: 80 SASCDCTVRLWDVARAKCLRVLKGHQRSVETVSFSPDSRQLASGGWDKRVMLW 132
Score = 76.3 bits (186), Expect = 2e-14
Identities = 50/143 (34%), Positives = 72/143 (50%), Gaps = 9/143 (6%)
Query: 52 LVSGSDDFTLFLW-----SPAEDKKPLTRMTGHQALINQVLFSPDSRIVASASFDKSIKL 106
L +GS D T+ +W +PA + L GH A I+ + +S S ++AS S+DK+I +
Sbjct: 162 LATGSWDSTVHIWDLRMVTPAVSHQALE---GHSANISCLCYSA-SGLLASGSWDKTIHI 217
Query: 107 WDGRTGKYLASLRGHVAAVYQIAWSADSRLLVSGSSDSTLKVWDVKAQKLAMDLPGHADE 166
W T L L+GHV V IA+S D L S +KVWD K L G D
Sbjct: 218 WKPTTSSLLIQLKGHVTWVKSIAFSPDELWLASAGYSRMVKVWDCNTGKCLETLKGVLDV 277
Query: 167 VYAVDWSPDGQRVASGGKDKCLR 189
+ ++PDG+ + SG D+ R
Sbjct: 278 AHTCAFTPDGKILVSGAADQTRR 300
>gi|21071067 TBP-associated factor 5 [Homo sapiens]
Length = 800
Score = 94.0 bits (232), Expect = 7e-20
Identities = 46/139 (33%), Positives = 77/139 (55%), Gaps = 1/139 (0%)
Query: 53 VSGSDDFTLFLWSPAEDKKPLTRMTGHQALINQVLFSPDSRIVASASFDKSIKLWDGRTG 112
VSG D LW+ + +PL GH A +N F P+S VA+ S D++++LWD G
Sbjct: 601 VSGGHDRVARLWA-TDHYQPLRIFAGHLADVNCTRFHPNSNYVATGSADRTVRLWDVLNG 659
Query: 113 KYLASLRGHVAAVYQIAWSADSRLLVSGSSDSTLKVWDVKAQKLAMDLPGHADEVYAVDW 172
+ GH ++ + +S + R L +G++D + +WD+ + +L GH D V ++ +
Sbjct: 660 NCVRIFTGHKGPIHSLTFSPNGRFLATGATDGRVLLWDIGHGLMVGELKGHTDTVCSLRF 719
Query: 173 SPDGQRVASGGKDKCLRIW 191
S DG+ +ASG D +R+W
Sbjct: 720 SRDGEILASGSMDNTVRLW 738
Score = 67.4 bits (163), Expect = 7e-12
Identities = 34/99 (34%), Positives = 55/99 (55%), Gaps = 1/99 (1%)
Query: 52 LVSGSDDFTLFLWSPAEDKKPLTRMTGHQALINQVLFSPDSRIVASASFDKSIKLWDGRT 111
+ +GS D T+ LW + TGH+ I+ + FSP+ R +A+ + D + LWD
Sbjct: 642 VATGSADRTVRLWDVLNGNC-VRIFTGHKGPIHSLTFSPNGRFLATGATDGRVLLWDIGH 700
Query: 112 GKYLASLRGHVAAVYQIAWSADSRLLVSGSSDSTLKVWD 150
G + L+GH V + +S D +L SGS D+T+++WD
Sbjct: 701 GLMVGELKGHTDTVCSLRFSRDGEILASGSMDNTVRLWD 739
Score = 66.6 bits (161), Expect = 1e-11
Identities = 42/145 (28%), Positives = 71/145 (48%), Gaps = 3/145 (2%)
Query: 49 PER--LVSGSDDFTLFLWSPAEDKKPLTRMTGHQALINQVLFSPDSRIVASASFDKSIKL 106
P+R L+S S+D T+ LWS + L GH + FSP S D+ +L
Sbjct: 553 PDRNYLLSSSEDGTVRLWS-LQTFTCLVGYKGHNYPVWDTQFSPYGYYFVSGGHDRVARL 611
Query: 107 WDGRTGKYLASLRGHVAAVYQIAWSADSRLLVSGSSDSTLKVWDVKAQKLAMDLPGHADE 166
W + L GH+A V + +S + +GS+D T+++WDV GH
Sbjct: 612 WATDHYQPLRIFAGHLADVNCTRFHPNSNYVATGSADRTVRLWDVLNGNCVRIFTGHKGP 671
Query: 167 VYAVDWSPDGQRVASGGKDKCLRIW 191
++++ +SP+G+ +A+G D + +W
Sbjct: 672 IHSLTFSPNGRFLATGATDGRVLLW 696
Score = 62.0 bits (149), Expect = 3e-10
Identities = 38/140 (27%), Positives = 61/140 (43%), Gaps = 12/140 (8%)
Query: 52 LVSGSDDFTLFLWSPAEDKKPLTRMTGHQALINQVLFSPDSRIVASASFDKSIKLWDGRT 111
+ G D T+ +WS K + V + D ++ S D ++ D +T
Sbjct: 485 IAGGFADSTVRVWSVTPKK------------LRSVKQASDLSLIDKESDDVLERIMDEKT 532
Query: 112 GKYLASLRGHVAAVYQIAWSADSRLLVSGSSDSTLKVWDVKAQKLAMDLPGHADEVYAVD 171
L L GH VY ++S D L+S S D T+++W ++ + GH V+
Sbjct: 533 ASELKILYGHSGPVYGASFSPDRNYLLSSSEDGTVRLWSLQTFTCLVGYKGHNYPVWDTQ 592
Query: 172 WSPDGQRVASGGKDKCLRIW 191
+SP G SGG D+ R+W
Sbjct: 593 FSPYGYYFVSGGHDRVARLW 612
Score = 61.2 bits (147), Expect = 5e-10
Identities = 32/114 (28%), Positives = 52/114 (45%)
Query: 78 GHQALINQVLFSPDSRIVASASFDKSIKLWDGRTGKYLASLRGHVAAVYQIAWSADSRLL 137
GH + FSPD + S+S D +++LW +T L +GH V+ +S
Sbjct: 541 GHSGPVYGASFSPDRNYLLSSSEDGTVRLWSLQTFTCLVGYKGHNYPVWDTQFSPYGYYF 600
Query: 138 VSGSSDSTLKVWDVKAQKLAMDLPGHADEVYAVDWSPDGQRVASGGKDKCLRIW 191
VSG D ++W + GH +V + P+ VA+G D+ +R+W
Sbjct: 601 VSGGHDRVARLWATDHYQPLRIFAGHLADVNCTRFHPNSNYVATGSADRTVRLW 654
Score = 38.9 bits (89), Expect = 0.003
Identities = 26/90 (28%), Positives = 37/90 (41%), Gaps = 31/90 (34%)
Query: 133 DSRLLVSGSSDSTLKVWDVKAQKL-----AMDLP-------------------------- 161
DS L+ G +DST++VW V +KL A DL
Sbjct: 481 DSSLIAGGFADSTVRVWSVTPKKLRSVKQASDLSLIDKESDDVLERIMDEKTASELKILY 540
Query: 162 GHADEVYAVDWSPDGQRVASGGKDKCLRIW 191
GH+ VY +SPD + S +D +R+W
Sbjct: 541 GHSGPVYGASFSPDRNYLLSSSEDGTVRLW 570
>gi|32189425 WD repeat domain 69 [Homo sapiens]
Length = 415
Score = 94.0 bits (232), Expect = 7e-20
Identities = 49/160 (30%), Positives = 87/160 (54%), Gaps = 2/160 (1%)
Query: 33 LKERALSRYNLVRGQGPERLVSGSDDFTLFLWSPAEDKKPLTRMTGHQALINQVLF-SPD 91
LK L N+ + ++GS D T LW A ++ L + GH+ ++ + F +P
Sbjct: 88 LKAHILPLTNVALNKSGSCFITGSYDRTCKLWDTASGEE-LNTLEGHRNVVYAIAFNNPY 146
Query: 92 SRIVASASFDKSIKLWDGRTGKYLASLRGHVAAVYQIAWSADSRLLVSGSSDSTLKVWDV 151
+A+ SFDK+ KLW TGK + RGH A + ++++ S L+ +GS D+T K+WD+
Sbjct: 147 GDKIATGSFDKTCKLWSVETGKCYHTFRGHTAEIVCLSFNPQSTLVATGSMDTTAKLWDI 206
Query: 152 KAQKLAMDLPGHADEVYAVDWSPDGQRVASGGKDKCLRIW 191
+ + L GH+ E+ ++ ++ G R+ +G D + +W
Sbjct: 207 QNGEEVYTLRGHSAEIISLSFNTSGDRIITGSFDHTVVVW 246
Score = 92.8 bits (229), Expect = 2e-19
Identities = 43/142 (30%), Positives = 77/142 (54%), Gaps = 1/142 (0%)
Query: 50 ERLVSGSDDFTLFLWSPAEDKKPLTRMTGHQALINQVLFSPDSRIVASASFDKSIKLWDG 109
+R+++GS D T+ +W A+ + + + GH A I+ F+ D ++ + S DK+ KLWD
Sbjct: 232 DRIITGSFDHTVVVWD-ADTGRKVNILIGHCAEISSASFNWDCSLILTGSMDKTCKLWDA 290
Query: 110 RTGKYLASLRGHVAAVYQIAWSADSRLLVSGSSDSTLKVWDVKAQKLAMDLPGHADEVYA 169
GK +A+L GH + + +L+ + S+D T +++ +K L GH E+
Sbjct: 291 TNGKCVATLTGHDDEILDSCFDYTGKLIATASADGTARIFSAATRKCIAKLEGHEGEISK 350
Query: 170 VDWSPDGQRVASGGKDKCLRIW 191
+ ++P G + +G DK RIW
Sbjct: 351 ISFNPQGNHLLTGSSDKTARIW 372
Score = 89.4 bits (220), Expect = 2e-18
Identities = 46/141 (32%), Positives = 78/141 (55%), Gaps = 1/141 (0%)
Query: 52 LVSGSDDFTLFLWSPAEDKKPLTRMTGHQALINQVLFSPDSRIVASASFDKSIKLWDGRT 111
+++GS D T LW A + K + +TGH I F +++A+AS D + +++ T
Sbjct: 276 ILTGSMDKTCKLWD-ATNGKCVATLTGHDDEILDSCFDYTGKLIATASADGTARIFSAAT 334
Query: 112 GKYLASLRGHVAAVYQIAWSADSRLLVSGSSDSTLKVWDVKAQKLAMDLPGHADEVYAVD 171
K +A L GH + +I+++ L++GSSD T ++WD + + L GH DE+++
Sbjct: 335 RKCIAKLEGHEGEISKISFNPQGNHLLTGSSDKTARIWDAQTGQCLQVLEGHTDEIFSCA 394
Query: 172 WSPDGQRVASGGKDKCLRIWR 192
++ G V +G KD RIWR
Sbjct: 395 FNYKGNIVITGSKDNTCRIWR 415
Score = 87.0 bits (214), Expect = 9e-18
Identities = 46/142 (32%), Positives = 77/142 (54%), Gaps = 1/142 (0%)
Query: 50 ERLVSGSDDFTLFLWSPAEDKKPLTRMTGHQALINQVLFSPDSRIVASASFDKSIKLWDG 109
+++ +GS D T LWS E K GH A I + F+P S +VA+ S D + KLWD
Sbjct: 148 DKIATGSFDKTCKLWS-VETGKCYHTFRGHTAEIVCLSFNPQSTLVATGSMDTTAKLWDI 206
Query: 110 RTGKYLASLRGHVAAVYQIAWSADSRLLVSGSSDSTLKVWDVKAQKLAMDLPGHADEVYA 169
+ G+ + +LRGH A + ++++ +++GS D T+ VWD + L GH E+ +
Sbjct: 207 QNGEEVYTLRGHSAEIISLSFNTSGDRIITGSFDHTVVVWDADTGRKVNILIGHCAEISS 266
Query: 170 VDWSPDGQRVASGGKDKCLRIW 191
++ D + +G DK ++W
Sbjct: 267 ASFNWDCSLILTGSMDKTCKLW 288
Score = 76.6 bits (187), Expect = 1e-14
Identities = 43/140 (30%), Positives = 71/140 (50%), Gaps = 1/140 (0%)
Query: 52 LVSGSDDFTLFLWSPAEDKKPLTRMTGHQALINQVLFSPDSRIVASASFDKSIKLWDGRT 111
+ +GS D T LW ++ T + GH A I + F+ + + SFD ++ +WD T
Sbjct: 192 VATGSMDTTAKLWDIQNGEEVYT-LRGHSAEIISLSFNTSGDRIITGSFDHTVVVWDADT 250
Query: 112 GKYLASLRGHVAAVYQIAWSADSRLLVSGSSDSTLKVWDVKAQKLAMDLPGHADEVYAVD 171
G+ + L GH A + +++ D L+++GS D T K+WD K L GH DE+
Sbjct: 251 GRKVNILIGHCAEISSASFNWDCSLILTGSMDKTCKLWDATNGKCVATLTGHDDEILDSC 310
Query: 172 WSPDGQRVASGGKDKCLRIW 191
+ G+ +A+ D RI+
Sbjct: 311 FDYTGKLIATASADGTARIF 330
>gi|24431950 PRP4 pre-mRNA processing factor 4 homolog [Homo
sapiens]
Length = 522
Score = 92.8 bits (229), Expect = 2e-19
Identities = 44/140 (31%), Positives = 77/140 (55%), Gaps = 1/140 (0%)
Query: 52 LVSGSDDFTLFLWSPAEDKKPLTRMTGHQALINQVLFSPDSRIVASASFDKSIKLWDGRT 111
L S + D ++ LWS D+ P+ + GH + +V++ P R + + +D+S +LWD
Sbjct: 296 LASCAADGSVKLWSLDSDE-PVADIEGHTVRVARVMWHPSGRFLGTTCYDRSWRLWDLEA 354
Query: 112 GKYLASLRGHVAAVYQIAWSADSRLLVSGSSDSTLKVWDVKAQKLAMDLPGHADEVYAVD 171
+ + GH VY IA+ D L +G D+ +VWD++ + M L GH E+Y ++
Sbjct: 355 QEEILHQEGHSMGVYDIAFHQDGSLAGTGGLDAFGRVWDLRTGRCIMFLEGHLKEIYGIN 414
Query: 172 WSPDGQRVASGGKDKCLRIW 191
+SP+G +A+G D ++W
Sbjct: 415 FSPNGYHIATGSGDNTCKVW 434
Score = 74.7 bits (182), Expect = 5e-14
Identities = 37/130 (28%), Positives = 65/130 (50%), Gaps = 2/130 (1%)
Query: 63 LWSPAEDKKPLTRMTGHQALINQVLFSPDSRIVASASFDKSIKLWDGRTGKYLASLRGHV 122
LW E ++ + GH + + F D + + D ++WD RTG+ + L GH+
Sbjct: 349 LWD-LEAQEEILHQEGHSMGVYDIAFHQDGSLAGTGGLDAFGRVWDLRTGRCIMFLEGHL 407
Query: 123 AAVYQIAWSADSRLLVSGSSDSTLKVWDVKAQKLAMDLPGHADEVYAVDWSP-DGQRVAS 181
+Y I +S + + +GS D+T KVWD++ ++ +P H + V V + P G + +
Sbjct: 408 KEIYGINFSPNGYHIATGSGDNTCKVWDLRQRRCVYTIPAHQNLVTGVKFEPIHGNFLLT 467
Query: 182 GGKDKCLRIW 191
G D +IW
Sbjct: 468 GAYDNTAKIW 477
Score = 73.2 bits (178), Expect = 1e-13
Identities = 40/137 (29%), Positives = 67/137 (48%), Gaps = 9/137 (6%)
Query: 63 LWSPAEDKKPLTRMTGHQALINQVLFSPDSRI--------VASASFDKSIKLWDGRTGKY 114
LWS D L + GH + ++F P S + +AS + D S+KLW + +
Sbjct: 257 LWS-VPDCNLLHTLRGHNTNVGAIVFHPKSTVSLDPKDVNLASCAADGSVKLWSLDSDEP 315
Query: 115 LASLRGHVAAVYQIAWSADSRLLVSGSSDSTLKVWDVKAQKLAMDLPGHADEVYAVDWSP 174
+A + GH V ++ W R L + D + ++WD++AQ+ + GH+ VY + +
Sbjct: 316 VADIEGHTVRVARVMWHPSGRFLGTTCYDRSWRLWDLEAQEEILHQEGHSMGVYDIAFHQ 375
Query: 175 DGQRVASGGKDKCLRIW 191
DG +GG D R+W
Sbjct: 376 DGSLAGTGGLDAFGRVW 392
Score = 60.1 bits (144), Expect = 1e-09
Identities = 33/117 (28%), Positives = 58/117 (49%), Gaps = 1/117 (0%)
Query: 76 MTGHQALINQVLFSPDSRIVASASFDKSIKLWDGRTGKYLASLRGHVAAVYQIAWSA-DS 134
+ GH I + FSP+ +A+ S D + K+WD R + + ++ H V + +
Sbjct: 403 LEGHLKEIYGINFSPNGYHIATGSGDNTCKVWDLRQRRCVYTIPAHQNLVTGVKFEPIHG 462
Query: 135 RLLVSGSSDSTLKVWDVKAQKLAMDLPGHADEVYAVDWSPDGQRVASGGKDKCLRIW 191
L++G+ D+T K+W L GH +V +D S DGQ +A+ D+ ++W
Sbjct: 463 NFLLTGAYDNTAKIWTHPGWSPLKTLAGHEGKVMGLDISSDGQLIATCSYDRTFKLW 519
Score = 57.8 bits (138), Expect = 6e-09
Identities = 35/122 (28%), Positives = 59/122 (48%), Gaps = 8/122 (6%)
Query: 78 GHQALINQVLFSPDSRIVASASFDKSIKLWDGRTGKYLASLRGHVAAVYQIAWSADSRL- 136
G I+ FSP+S+++A+A + KLW L +LRGH V I + S +
Sbjct: 229 GDDRPISYCHFSPNSKMLATACWSGLCKLWSVPDCNLLHTLRGHNTNVGAIVFHPKSTVS 288
Query: 137 -------LVSGSSDSTLKVWDVKAQKLAMDLPGHADEVYAVDWSPDGQRVASGGKDKCLR 189
L S ++D ++K+W + + + D+ GH V V W P G+ + + D+ R
Sbjct: 289 LDPKDVNLASCAADGSVKLWSLDSDEPVADIEGHTVRVARVMWHPSGRFLGTTCYDRSWR 348
Query: 190 IW 191
+W
Sbjct: 349 LW 350
Score = 37.7 bits (86), Expect = 0.006
Identities = 17/56 (30%), Positives = 33/56 (58%), Gaps = 1/56 (1%)
Query: 52 LVSGSDDFTLFLWSPAEDKKPLTRMTGHQALINQVLFSPDSRIVASASFDKSIKLW 107
L++G+ D T +W+ PL + GH+ + + S D +++A+ S+D++ KLW
Sbjct: 465 LLTGAYDNTAKIWTHP-GWSPLKTLAGHEGKVMGLDISSDGQLIATCSYDRTFKLW 519
>gi|4557741 platelet-activating factor acetylhydrolase, isoform Ib,
alpha subunit [Homo sapiens]
Length = 410
Score = 91.3 bits (225), Expect = 5e-19
Identities = 50/167 (29%), Positives = 87/167 (52%), Gaps = 14/167 (8%)
Query: 25 DLQGSLQELKERALSRYNLVRGQGPERLVSGSDDFTLFLWSPAEDKKPLTRMTGHQALIN 84
+L+ L E KE S L + + P+ W P +K ++GH++ +
Sbjct: 67 ELESKLNEAKEEFTSGGPLGQKRDPKE------------WIPRPPEK--YALSGHRSPVT 112
Query: 85 QVLFSPDSRIVASASFDKSIKLWDGRTGKYLASLRGHVAAVYQIAWSADSRLLVSGSSDS 144
+V+F P ++ SAS D +IK+WD TG + +L+GH +V I++ +LL S S+D
Sbjct: 113 RVIFHPVFSVMVSASEDATIKVWDYETGDFERTLKGHTDSVQDISFDHSGKLLASCSADM 172
Query: 145 TLKVWDVKAQKLAMDLPGHADEVYAVDWSPDGQRVASGGKDKCLRIW 191
T+K+WD + + + GH V +V P+G + S +DK +++W
Sbjct: 173 TIKLWDFQGFECIRTMHGHDHNVSSVAIMPNGDHIVSASRDKTIKMW 219
Score = 75.5 bits (184), Expect = 3e-14
Identities = 42/140 (30%), Positives = 71/140 (50%), Gaps = 1/140 (0%)
Query: 52 LVSGSDDFTLFLWSPAEDKKPLTRMTGHQALINQVLFSPDSRIVASASFDKSIKLWDGRT 111
+VS S+D T+ +W T + GH + + F +++AS S D +IKLWD +
Sbjct: 123 MVSASEDATIKVWDYETGDFERT-LKGHTDSVQDISFDHSGKLLASCSADMTIKLWDFQG 181
Query: 112 GKYLASLRGHVAAVYQIAWSADSRLLVSGSSDSTLKVWDVKAQKLAMDLPGHADEVYAVD 171
+ + ++ GH V +A + +VS S D T+K+W+V+ GH + V V
Sbjct: 182 FECIRTMHGHDHNVSSVAIMPNGDHIVSASRDKTIKMWEVQTGYCVKTFTGHREWVRMVR 241
Query: 172 WSPDGQRVASGGKDKCLRIW 191
+ DG +AS D+ +R+W
Sbjct: 242 PNQDGTLIASCSNDQTVRVW 261
Score = 74.3 bits (181), Expect = 6e-14
Identities = 45/160 (28%), Positives = 76/160 (47%), Gaps = 21/160 (13%)
Query: 52 LVSGSDDFTLFLWSPAEDKKPLTRMTGHQALINQVLFSPDSRIVASASFDKSIKLWDGRT 111
L S S D T+ LW + + + M GH ++ V P+ + SAS DK+IK+W+ +T
Sbjct: 165 LASCSADMTIKLWD-FQGFECIRTMHGHDHNVSSVAIMPNGDHIVSASRDKTIKMWEVQT 223
Query: 112 GKYLASLRGHVAAVYQIAWSADSRLLVSGSSDSTLKVWDVKAQKLAMDLPGHADEVYAVD 171
G + + GH V + + D L+ S S+D T++VW V ++ +L H V +
Sbjct: 224 GYCVKTFTGHREWVRMVRPNQDGTLIASCSNDQTVRVWVVATKECKAELREHEHVVECIS 283
Query: 172 WSPD--------------------GQRVASGGKDKCLRIW 191
W+P+ G + SG +DK +++W
Sbjct: 284 WAPESSYSSISEATGSETKKSGKPGPFLLSGSRDKTIKMW 323
Score = 64.7 bits (156), Expect = 5e-11
Identities = 35/128 (27%), Positives = 62/128 (48%), Gaps = 4/128 (3%)
Query: 64 WSPAEDKKPLTRMTGHQALINQVLFSPDSRIVASASFDKSIKLWDGRTGKYLASLRGHVA 123
W+P ++ TG + + + S S DK+IK+WD TG L +L GH
Sbjct: 284 WAPESSYSSISEATGSETKKS----GKPGPFLLSGSRDKTIKMWDVSTGMCLMTLVGHDN 339
Query: 124 AVYQIAWSADSRLLVSGSSDSTLKVWDVKAQKLAMDLPGHADEVYAVDWSPDGQRVASGG 183
V + + + + ++S + D TL+VWD K ++ L H V ++D+ V +G
Sbjct: 340 WVRGVLFHSGGKFILSCADDKTLRVWDYKNKRCMKTLNAHEHFVTSLDFHKTAPYVVTGS 399
Query: 184 KDKCLRIW 191
D+ +++W
Sbjct: 400 VDQTVKVW 407
Score = 57.8 bits (138), Expect = 6e-09
Identities = 29/101 (28%), Positives = 55/101 (54%), Gaps = 1/101 (0%)
Query: 52 LVSGSDDFTLFLWSPAEDKKPLTRMTGHQALINQVLFSPDSRIVASASFDKSIKLWDGRT 111
L+SGS D T+ +W + +T + GH + VLF + + S + DK++++WD +
Sbjct: 311 LLSGSRDKTIKMWDVSTGMCLMT-LVGHDNWVRGVLFHSGGKFILSCADDKTLRVWDYKN 369
Query: 112 GKYLASLRGHVAAVYQIAWSADSRLLVSGSSDSTLKVWDVK 152
+ + +L H V + + + +V+GS D T+KVW+ +
Sbjct: 370 KRCMKTLNAHEHFVTSLDFHKTAPYVVTGSVDQTVKVWECR 410
>gi|239787760 WD repeat domain 51A isoform 2 [Homo sapiens]
Length = 359
Score = 89.4 bits (220), Expect = 2e-18
Identities = 46/142 (32%), Positives = 71/142 (50%), Gaps = 1/142 (0%)
Query: 50 ERLVSGSDDFTLFLWSPAEDKKPLTRMTGHQALINQVLFSPDSRIVASASFDKSIKLWDG 109
++L SGS D L +W + R TGH+ + V FSP ++AS S DK++++W
Sbjct: 32 KQLASGSMDSCLMVWHMKPQSRAY-RFTGHKDAVTCVNFSPSGHLLASGSRDKTVRIWVP 90
Query: 110 RTGKYLASLRGHVAAVYQIAWSADSRLLVSGSSDSTLKVWDVKAQKLAMDLPGHADEVYA 169
R H A V + + +D + V+ S D T+KVW QK L H + V
Sbjct: 91 NVKGESTVFRAHTATVRSVHFCSDGQSFVTASDDKTVKVWATHRQKFLFSLSQHINWVRC 150
Query: 170 VDWSPDGQRVASGGKDKCLRIW 191
+SPDG+ + S DK +++W
Sbjct: 151 AKFSPDGRLIVSASDDKTVKLW 172
Score = 87.4 bits (215), Expect = 7e-18
Identities = 49/140 (35%), Positives = 72/140 (51%), Gaps = 1/140 (0%)
Query: 52 LVSGSDDFTLFLWSPAEDKKPLTRMTGHQALINQVLFSPDSRIVASASFDKSIKLWDGRT 111
L SGS D T+ +W P K T H A + V F D + +AS DK++K+W
Sbjct: 76 LASGSRDKTVRIWVP-NVKGESTVFRAHTATVRSVHFCSDGQSFVTASDDKTVKVWATHR 134
Query: 112 GKYLASLRGHVAAVYQIAWSADSRLLVSGSSDSTLKVWDVKAQKLAMDLPGHADEVYAVD 171
K+L SL H+ V +S D RL+VS S D T+K+WD +++ H V VD
Sbjct: 135 QKFLFSLSQHINWVRCAKFSPDGRLIVSASDDKTVKLWDKSSRECVHSYCEHGGFVTYVD 194
Query: 172 WSPDGQRVASGGKDKCLRIW 191
+ P G +A+ G D +++W
Sbjct: 195 FHPSGTCIAAAGMDNTVKVW 214
Score = 86.3 bits (212), Expect = 1e-17
Identities = 47/141 (33%), Positives = 75/141 (53%), Gaps = 1/141 (0%)
Query: 52 LVSGSDDFTLFLWSPAEDKKPLTRMTGHQALINQVLFSPDSRIVASASFDKSIKLWDGRT 111
+VS SDD T+ LW + ++ + H + V F P +A+A D ++K+WD RT
Sbjct: 160 IVSASDDKTVKLWDKSS-RECVHSYCEHGGFVTYVDFHPSGTCIAAAGMDNTVKVWDVRT 218
Query: 112 GKYLASLRGHVAAVYQIAWSADSRLLVSGSSDSTLKVWDVKAQKLAMDLPGHADEVYAVD 171
+ L + H AAV +++ L++ SSDSTLK+ D+ +L L GH V
Sbjct: 219 HRLLQHYQLHSAAVNGLSFHPSGNYLITASSDSTLKILDLMEGRLLYTLHGHQGPATTVA 278
Query: 172 WSPDGQRVASGGKDKCLRIWR 192
+S G+ ASGG D+ + +W+
Sbjct: 279 FSRTGEYFASGGSDEQVMVWK 299
Score = 74.7 bits (182), Expect = 5e-14
Identities = 41/141 (29%), Positives = 71/141 (50%), Gaps = 1/141 (0%)
Query: 50 ERLVSGSDDFTLFLWSPAEDKKPLTRMTGHQALINQVLFSPDSRIVASASFDKSIKLWDG 109
+ V+ SDD T+ +W+ +K L ++ H + FSPD R++ SAS DK++KLWD
Sbjct: 116 QSFVTASDDKTVKVWA-THRQKFLFSLSQHINWVRCAKFSPDGRLIVSASDDKTVKLWDK 174
Query: 110 RTGKYLASLRGHVAAVYQIAWSADSRLLVSGSSDSTLKVWDVKAQKLAMDLPGHADEVYA 169
+ + + S H V + + + + D+T+KVWDV+ +L H+ V
Sbjct: 175 SSRECVHSYCEHGGFVTYVDFHPSGTCIAAAGMDNTVKVWDVRTHRLLQHYQLHSAAVNG 234
Query: 170 VDWSPDGQRVASGGKDKCLRI 190
+ + P G + + D L+I
Sbjct: 235 LSFHPSGNYLITASSDSTLKI 255
Score = 66.6 bits (161), Expect = 1e-11
Identities = 33/73 (45%), Positives = 45/73 (61%)
Query: 119 RGHVAAVYQIAWSADSRLLVSGSSDSTLKVWDVKAQKLAMDLPGHADEVYAVDWSPDGQR 178
+GH AV + +S +++ L SGS DS L VW +K Q A GH D V V++SP G
Sbjct: 16 KGHRDAVTCVDFSINTKQLASGSMDSCLMVWHMKPQSRAYRFTGHKDAVTCVNFSPSGHL 75
Query: 179 VASGGKDKCLRIW 191
+ASG +DK +RIW
Sbjct: 76 LASGSRDKTVRIW 88
Score = 62.4 bits (150), Expect = 2e-10
Identities = 35/125 (28%), Positives = 57/125 (45%)
Query: 67 AEDKKPLTRMTGHQALINQVLFSPDSRIVASASFDKSIKLWDGRTGKYLASLRGHVAAVY 126
AED GH+ + V FS +++ +AS S D + +W + GH AV
Sbjct: 6 AEDPSLERHFKGHRDAVTCVDFSINTKQLASGSMDSCLMVWHMKPQSRAYRFTGHKDAVT 65
Query: 127 QIAWSADSRLLVSGSSDSTLKVWDVKAQKLAMDLPGHADEVYAVDWSPDGQRVASGGKDK 186
+ +S LL SGS D T+++W + + H V +V + DGQ + DK
Sbjct: 66 CVNFSPSGHLLASGSRDKTVRIWVPNVKGESTVFRAHTATVRSVHFCSDGQSFVTASDDK 125
Query: 187 CLRIW 191
+++W
Sbjct: 126 TVKVW 130
>gi|239787754 WD repeat domain 51A isoform 1 [Homo sapiens]
Length = 407
Score = 89.4 bits (220), Expect = 2e-18
Identities = 46/142 (32%), Positives = 71/142 (50%), Gaps = 1/142 (0%)
Query: 50 ERLVSGSDDFTLFLWSPAEDKKPLTRMTGHQALINQVLFSPDSRIVASASFDKSIKLWDG 109
++L SGS D L +W + R TGH+ + V FSP ++AS S DK++++W
Sbjct: 32 KQLASGSMDSCLMVWHMKPQSRAY-RFTGHKDAVTCVNFSPSGHLLASGSRDKTVRIWVP 90
Query: 110 RTGKYLASLRGHVAAVYQIAWSADSRLLVSGSSDSTLKVWDVKAQKLAMDLPGHADEVYA 169
R H A V + + +D + V+ S D T+KVW QK L H + V
Sbjct: 91 NVKGESTVFRAHTATVRSVHFCSDGQSFVTASDDKTVKVWATHRQKFLFSLSQHINWVRC 150
Query: 170 VDWSPDGQRVASGGKDKCLRIW 191
+SPDG+ + S DK +++W
Sbjct: 151 AKFSPDGRLIVSASDDKTVKLW 172
Score = 87.4 bits (215), Expect = 7e-18
Identities = 49/140 (35%), Positives = 72/140 (51%), Gaps = 1/140 (0%)
Query: 52 LVSGSDDFTLFLWSPAEDKKPLTRMTGHQALINQVLFSPDSRIVASASFDKSIKLWDGRT 111
L SGS D T+ +W P K T H A + V F D + +AS DK++K+W
Sbjct: 76 LASGSRDKTVRIWVP-NVKGESTVFRAHTATVRSVHFCSDGQSFVTASDDKTVKVWATHR 134
Query: 112 GKYLASLRGHVAAVYQIAWSADSRLLVSGSSDSTLKVWDVKAQKLAMDLPGHADEVYAVD 171
K+L SL H+ V +S D RL+VS S D T+K+WD +++ H V VD
Sbjct: 135 QKFLFSLSQHINWVRCAKFSPDGRLIVSASDDKTVKLWDKSSRECVHSYCEHGGFVTYVD 194
Query: 172 WSPDGQRVASGGKDKCLRIW 191
+ P G +A+ G D +++W
Sbjct: 195 FHPSGTCIAAAGMDNTVKVW 214
Score = 86.3 bits (212), Expect = 1e-17
Identities = 47/141 (33%), Positives = 75/141 (53%), Gaps = 1/141 (0%)
Query: 52 LVSGSDDFTLFLWSPAEDKKPLTRMTGHQALINQVLFSPDSRIVASASFDKSIKLWDGRT 111
+VS SDD T+ LW + ++ + H + V F P +A+A D ++K+WD RT
Sbjct: 160 IVSASDDKTVKLWDKSS-RECVHSYCEHGGFVTYVDFHPSGTCIAAAGMDNTVKVWDVRT 218
Query: 112 GKYLASLRGHVAAVYQIAWSADSRLLVSGSSDSTLKVWDVKAQKLAMDLPGHADEVYAVD 171
+ L + H AAV +++ L++ SSDSTLK+ D+ +L L GH V
Sbjct: 219 HRLLQHYQLHSAAVNGLSFHPSGNYLITASSDSTLKILDLMEGRLLYTLHGHQGPATTVA 278
Query: 172 WSPDGQRVASGGKDKCLRIWR 192
+S G+ ASGG D+ + +W+
Sbjct: 279 FSRTGEYFASGGSDEQVMVWK 299
Score = 74.7 bits (182), Expect = 5e-14
Identities = 41/141 (29%), Positives = 71/141 (50%), Gaps = 1/141 (0%)
Query: 50 ERLVSGSDDFTLFLWSPAEDKKPLTRMTGHQALINQVLFSPDSRIVASASFDKSIKLWDG 109
+ V+ SDD T+ +W+ +K L ++ H + FSPD R++ SAS DK++KLWD
Sbjct: 116 QSFVTASDDKTVKVWA-THRQKFLFSLSQHINWVRCAKFSPDGRLIVSASDDKTVKLWDK 174
Query: 110 RTGKYLASLRGHVAAVYQIAWSADSRLLVSGSSDSTLKVWDVKAQKLAMDLPGHADEVYA 169
+ + + S H V + + + + D+T+KVWDV+ +L H+ V
Sbjct: 175 SSRECVHSYCEHGGFVTYVDFHPSGTCIAAAGMDNTVKVWDVRTHRLLQHYQLHSAAVNG 234
Query: 170 VDWSPDGQRVASGGKDKCLRI 190
+ + P G + + D L+I
Sbjct: 235 LSFHPSGNYLITASSDSTLKI 255
Score = 66.6 bits (161), Expect = 1e-11
Identities = 33/73 (45%), Positives = 45/73 (61%)
Query: 119 RGHVAAVYQIAWSADSRLLVSGSSDSTLKVWDVKAQKLAMDLPGHADEVYAVDWSPDGQR 178
+GH AV + +S +++ L SGS DS L VW +K Q A GH D V V++SP G
Sbjct: 16 KGHRDAVTCVDFSINTKQLASGSMDSCLMVWHMKPQSRAYRFTGHKDAVTCVNFSPSGHL 75
Query: 179 VASGGKDKCLRIW 191
+ASG +DK +RIW
Sbjct: 76 LASGSRDKTVRIW 88
Score = 62.4 bits (150), Expect = 2e-10
Identities = 35/125 (28%), Positives = 57/125 (45%)
Query: 67 AEDKKPLTRMTGHQALINQVLFSPDSRIVASASFDKSIKLWDGRTGKYLASLRGHVAAVY 126
AED GH+ + V FS +++ +AS S D + +W + GH AV
Sbjct: 6 AEDPSLERHFKGHRDAVTCVDFSINTKQLASGSMDSCLMVWHMKPQSRAYRFTGHKDAVT 65
Query: 127 QIAWSADSRLLVSGSSDSTLKVWDVKAQKLAMDLPGHADEVYAVDWSPDGQRVASGGKDK 186
+ +S LL SGS D T+++W + + H V +V + DGQ + DK
Sbjct: 66 CVNFSPSGHLLASGSRDKTVRIWVPNVKGESTVFRAHTATVRSVHFCSDGQSFVTASDDK 125
Query: 187 CLRIW 191
+++W
Sbjct: 126 TVKVW 130
>gi|5174447 guanine nucleotide binding protein (G protein), beta
polypeptide 2-like 1 [Homo sapiens]
Length = 317
Score = 88.2 bits (217), Expect = 4e-18
Identities = 48/152 (31%), Positives = 81/152 (53%), Gaps = 7/152 (4%)
Query: 47 QGPERLVSGSDDFTLFLWSPAEDKK----PLTRMTGHQALINQVLFSPDSRIVASASFDK 102
Q P+ ++S S D T+ +W D+ P + GH ++ V+ S D + S S+D
Sbjct: 26 QFPDMILSASRDKTIIMWKLTRDETNYGIPQRALRGHSHFVSDVVISSDGQFALSGSWDG 85
Query: 103 SIKLWDGRTGKYLASLRGHVAAVYQIAWSADSRLLVSGSSDSTLKVWD-VKAQKLAMDLP 161
+++LWD TG GH V +A+S+D+R +VSGS D T+K+W+ + K +
Sbjct: 86 TLRLWDLTTGTTTRRFVGHTKDVLSVAFSSDNRQIVSGSRDKTIKLWNTLGVCKYTVQDE 145
Query: 162 GHADEVYAVDWSPDGQR--VASGGKDKCLRIW 191
H++ V V +SP+ + S G DK +++W
Sbjct: 146 SHSEWVSCVRFSPNSSNPIIVSCGWDKLVKVW 177
Score = 59.3 bits (142), Expect = 2e-09
Identities = 39/127 (30%), Positives = 61/127 (48%), Gaps = 3/127 (2%)
Query: 51 RLVSGSDDFTLFLWSPAEDKKPLTRMTGHQALINQVLFSPDSR--IVASASFDKSIKLWD 108
++VSGS D T+ LW+ K + H ++ V FSP+S I+ S +DK +K+W+
Sbjct: 119 QIVSGSRDKTIKLWNTLGVCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCGWDKLVKVWN 178
Query: 109 GRTGKYLASLRGHVAAVYQIAWSADSRLLVSGSSDSTLKVWDVKAQKLAMDLPGHADEVY 168
K + GH + + S D L SG D +WD+ K L G D +
Sbjct: 179 LANCKLKTNHIGHTGYLNTVTVSPDGSLCASGGKDGQAMLWDLNEGKHLYTLDG-GDIIN 237
Query: 169 AVDWSPD 175
A+ +SP+
Sbjct: 238 ALCFSPN 244
Score = 59.3 bits (142), Expect = 2e-09
Identities = 39/150 (26%), Positives = 69/150 (46%), Gaps = 12/150 (8%)
Query: 52 LVSGSDDFTLFLWSPAEDKKPLTRMTGHQALINQVLFSPDSRIVASASFDKSIKLWDGRT 111
+VS D + +W+ A K T GH +N V SPD + AS D LWD
Sbjct: 165 IVSCGWDKLVKVWNLANCKLK-TNHIGHTGYLNTVTVSPDGSLCASGGKDGQAMLWDLNE 223
Query: 112 GKYLASLRGHVAAVYQIAWSADSRLLVSGSSDSTLKVWDVKAQKLAMDLP---------G 162
GK+L +L G + + +R + ++ ++K+WD++ + + +L
Sbjct: 224 GKHLYTLDG--GDIINALCFSPNRYWLCAATGPSIKIWDLEGKIIVDELKQEVISTSSKA 281
Query: 163 HADEVYAVDWSPDGQRVASGGKDKCLRIWR 192
+ ++ WS DGQ + +G D +R+W+
Sbjct: 282 EPPQCTSLAWSADGQTLFAGYTDNLVRVWQ 311
Score = 44.7 bits (104), Expect = 5e-05
Identities = 34/107 (31%), Positives = 49/107 (45%), Gaps = 12/107 (11%)
Query: 54 SGSDDFTLFLWSPAEDKKPLTRMTGHQALINQVLFSPDSRIVASASFDKSIKLWDGRTGK 113
SG D LW E K T G +IN + FSP+ R A+ SIK+WD
Sbjct: 209 SGGKDGQAMLWDLNEGKHLYTLDGGD--IINALCFSPN-RYWLCAATGPSIKIWDLEGKI 265
Query: 114 YLASLRGHVAAVYQ---------IAWSADSRLLVSGSSDSTLKVWDV 151
+ L+ V + +AWSAD + L +G +D+ ++VW V
Sbjct: 266 IVDELKQEVISTSSKAEPPQCTSLAWSADGQTLFAGYTDNLVRVWQV 312
>gi|26665869 WD repeat domain 51B [Homo sapiens]
Length = 478
Score = 88.2 bits (217), Expect = 4e-18
Identities = 47/143 (32%), Positives = 79/143 (55%), Gaps = 3/143 (2%)
Query: 50 ERLVSGSDDFTLFLWSPAEDKKPLTRMTGHQALINQVLFSPDSRIVASASFDKSIKLW-D 108
++L + S D L LW+ + R GH+ ++ V FSP ++ASAS D++++LW
Sbjct: 31 KQLATASWDTFLMLWNFKPHARAY-RYVGHKDVVTSVQFSPHGNLLASASRDRTVRLWIP 89
Query: 109 GRTGKYLASLRGHVAAVYQIAWSADSRLLVSGSSDSTLKVWDVKAQKLAMDLPGHADEVY 168
+ GK+ + + H A V + +SAD + L + S D ++KVW + Q+ L H V
Sbjct: 90 DKRGKF-SEFKAHTAPVRSVDFSADGQFLATASEDKSIKVWSMYRQRFLYSLYRHTHWVR 148
Query: 169 AVDWSPDGQRVASGGKDKCLRIW 191
+SPDG+ + S +DK ++IW
Sbjct: 149 CAKFSPDGRLIVSCSEDKTIKIW 171
Score = 87.8 bits (216), Expect = 5e-18
Identities = 50/140 (35%), Positives = 74/140 (52%), Gaps = 1/140 (0%)
Query: 52 LVSGSDDFTLFLWSPAEDKKPLTRMTGHQALINQVLFSPDSRIVASASFDKSIKLWDGRT 111
L S S D T+ LW P + K + H A + V FS D + +A+AS DKSIK+W
Sbjct: 75 LASASRDRTVRLWIPDKRGK-FSEFKAHTAPVRSVDFSADGQFLATASEDKSIKVWSMYR 133
Query: 112 GKYLASLRGHVAAVYQIAWSADSRLLVSGSSDSTLKVWDVKAQKLAMDLPGHADEVYAVD 171
++L SL H V +S D RL+VS S D T+K+WD ++ + VD
Sbjct: 134 QRFLYSLYRHTHWVRCAKFSPDGRLIVSCSEDKTIKIWDTTNKQCVNNFSDSVGFANFVD 193
Query: 172 WSPDGQRVASGGKDKCLRIW 191
++P G +AS G D+ +++W
Sbjct: 194 FNPSGTCIASAGSDQTVKVW 213
Score = 85.5 bits (210), Expect = 3e-17
Identities = 47/141 (33%), Positives = 74/141 (52%), Gaps = 1/141 (0%)
Query: 52 LVSGSDDFTLFLWSPAEDKKPLTRMTGHQALINQVLFSPDSRIVASASFDKSIKLWDGRT 111
+VS S+D T+ +W +K+ + + N V F+P +ASA D+++K+WD R
Sbjct: 159 IVSCSEDKTIKIWDTT-NKQCVNNFSDSVGFANFVDFNPSGTCIASAGSDQTVKVWDVRV 217
Query: 112 GKYLASLRGHVAAVYQIAWSADSRLLVSGSSDSTLKVWDVKAQKLAMDLPGHADEVYAVD 171
K L + H V I++ L++ SSD TLK+ D+ +L L GH V+ V
Sbjct: 218 NKLLQHYQVHSGGVNCISFHPSGNYLITASSDGTLKILDLLEGRLIYTLQGHTGPVFTVS 277
Query: 172 WSPDGQRVASGGKDKCLRIWR 192
+S G+ ASGG D + +WR
Sbjct: 278 FSKGGELFASGGADTQVLLWR 298
Score = 72.0 bits (175), Expect = 3e-13
Identities = 43/166 (25%), Positives = 74/166 (44%), Gaps = 1/166 (0%)
Query: 25 DLQGSLQELKERALSRYNLVRGQGPERLVSGSDDFTLFLWSPAEDKKPLTRMTGHQALIN 84
D +G E K ++ + L + S+D ++ +WS + L + H +
Sbjct: 90 DKRGKFSEFKAHTAPVRSVDFSADGQFLATASEDKSIKVWSMYRQRF-LYSLYRHTHWVR 148
Query: 85 QVLFSPDSRIVASASFDKSIKLWDGRTGKYLASLRGHVAAVYQIAWSADSRLLVSGSSDS 144
FSPD R++ S S DK+IK+WD + + + V + ++ + S SD
Sbjct: 149 CAKFSPDGRLIVSCSEDKTIKIWDTTNKQCVNNFSDSVGFANFVDFNPSGTCIASAGSDQ 208
Query: 145 TLKVWDVKAQKLAMDLPGHADEVYAVDWSPDGQRVASGGKDKCLRI 190
T+KVWDV+ KL H+ V + + P G + + D L+I
Sbjct: 209 TVKVWDVRVNKLLQHYQVHSGGVNCISFHPSGNYLITASSDGTLKI 254
Score = 68.9 bits (167), Expect = 2e-12
Identities = 38/127 (29%), Positives = 63/127 (49%)
Query: 65 SPAEDKKPLTRMTGHQALINQVLFSPDSRIVASASFDKSIKLWDGRTGKYLASLRGHVAA 124
S ED GH+A I + SP+ + +A+AS+D + LW+ + GH
Sbjct: 3 SATEDPVLERYFKGHKAAITSLDLSPNGKQLATASWDTFLMLWNFKPHARAYRYVGHKDV 62
Query: 125 VYQIAWSADSRLLVSGSSDSTLKVWDVKAQKLAMDLPGHADEVYAVDWSPDGQRVASGGK 184
V + +S LL S S D T+++W + + H V +VD+S DGQ +A+ +
Sbjct: 63 VTSVQFSPHGNLLASASRDRTVRLWIPDKRGKFSEFKAHTAPVRSVDFSADGQFLATASE 122
Query: 185 DKCLRIW 191
DK +++W
Sbjct: 123 DKSIKVW 129
Score = 52.4 bits (124), Expect = 2e-07
Identities = 33/141 (23%), Positives = 62/141 (43%), Gaps = 14/141 (9%)
Query: 52 LVSGSDDFTLFLWSPAEDKKPLTRMTGHQALINQVLFSPDSRIVASASFDKSIKLWDGRT 111
+ S D T+ +W +K L H +N + F P + +AS D ++K+ D
Sbjct: 201 IASAGSDQTVKVWDVRVNKL-LQHYQVHSGGVNCISFHPSGNYLITASSDGTLKILDLLE 259
Query: 112 GKYLASLRGHVAAVYQIAWSADSRLLVSGSSDSTLKVWDV-------------KAQKLAM 158
G+ + +L+GH V+ +++S L SG +D+ + +W ++L
Sbjct: 260 GRLIYTLQGHTGPVFTVSFSKGGELFASGGADTQVLLWRTNFDELHCKGLTKRNLKRLHF 319
Query: 159 DLPGHADEVYAVDWSPDGQRV 179
D P H ++Y P ++V
Sbjct: 320 DSPPHLLDIYPRTPHPHEEKV 340
>gi|239787764 WD repeat domain 51A isoform 3 [Homo sapiens]
Length = 369
Score = 87.4 bits (215), Expect = 7e-18
Identities = 49/140 (35%), Positives = 72/140 (51%), Gaps = 1/140 (0%)
Query: 52 LVSGSDDFTLFLWSPAEDKKPLTRMTGHQALINQVLFSPDSRIVASASFDKSIKLWDGRT 111
L SGS D T+ +W P K T H A + V F D + +AS DK++K+W
Sbjct: 38 LASGSRDKTVRIWVP-NVKGESTVFRAHTATVRSVHFCSDGQSFVTASDDKTVKVWATHR 96
Query: 112 GKYLASLRGHVAAVYQIAWSADSRLLVSGSSDSTLKVWDVKAQKLAMDLPGHADEVYAVD 171
K+L SL H+ V +S D RL+VS S D T+K+WD +++ H V VD
Sbjct: 97 QKFLFSLSQHINWVRCAKFSPDGRLIVSASDDKTVKLWDKSSRECVHSYCEHGGFVTYVD 156
Query: 172 WSPDGQRVASGGKDKCLRIW 191
+ P G +A+ G D +++W
Sbjct: 157 FHPSGTCIAAAGMDNTVKVW 176
Score = 86.3 bits (212), Expect = 1e-17
Identities = 47/141 (33%), Positives = 75/141 (53%), Gaps = 1/141 (0%)
Query: 52 LVSGSDDFTLFLWSPAEDKKPLTRMTGHQALINQVLFSPDSRIVASASFDKSIKLWDGRT 111
+VS SDD T+ LW + ++ + H + V F P +A+A D ++K+WD RT
Sbjct: 122 IVSASDDKTVKLWDKSS-RECVHSYCEHGGFVTYVDFHPSGTCIAAAGMDNTVKVWDVRT 180
Query: 112 GKYLASLRGHVAAVYQIAWSADSRLLVSGSSDSTLKVWDVKAQKLAMDLPGHADEVYAVD 171
+ L + H AAV +++ L++ SSDSTLK+ D+ +L L GH V
Sbjct: 181 HRLLQHYQLHSAAVNGLSFHPSGNYLITASSDSTLKILDLMEGRLLYTLHGHQGPATTVA 240
Query: 172 WSPDGQRVASGGKDKCLRIWR 192
+S G+ ASGG D+ + +W+
Sbjct: 241 FSRTGEYFASGGSDEQVMVWK 261
Score = 82.8 bits (203), Expect = 2e-16
Identities = 42/134 (31%), Positives = 65/134 (48%), Gaps = 1/134 (0%)
Query: 58 DFTLFLWSPAEDKKPLTRMTGHQALINQVLFSPDSRIVASASFDKSIKLWDGRTGKYLAS 117
D L +W + R TGH+ + V FSP ++AS S DK++++W
Sbjct: 2 DSCLMVWHMKPQSRAY-RFTGHKDAVTCVNFSPSGHLLASGSRDKTVRIWVPNVKGESTV 60
Query: 118 LRGHVAAVYQIAWSADSRLLVSGSSDSTLKVWDVKAQKLAMDLPGHADEVYAVDWSPDGQ 177
R H A V + + +D + V+ S D T+KVW QK L H + V +SPDG+
Sbjct: 61 FRAHTATVRSVHFCSDGQSFVTASDDKTVKVWATHRQKFLFSLSQHINWVRCAKFSPDGR 120
Query: 178 RVASGGKDKCLRIW 191
+ S DK +++W
Sbjct: 121 LIVSASDDKTVKLW 134
Score = 74.7 bits (182), Expect = 5e-14
Identities = 41/141 (29%), Positives = 71/141 (50%), Gaps = 1/141 (0%)
Query: 50 ERLVSGSDDFTLFLWSPAEDKKPLTRMTGHQALINQVLFSPDSRIVASASFDKSIKLWDG 109
+ V+ SDD T+ +W+ +K L ++ H + FSPD R++ SAS DK++KLWD
Sbjct: 78 QSFVTASDDKTVKVWA-THRQKFLFSLSQHINWVRCAKFSPDGRLIVSASDDKTVKLWDK 136
Query: 110 RTGKYLASLRGHVAAVYQIAWSADSRLLVSGSSDSTLKVWDVKAQKLAMDLPGHADEVYA 169
+ + + S H V + + + + D+T+KVWDV+ +L H+ V
Sbjct: 137 SSRECVHSYCEHGGFVTYVDFHPSGTCIAAAGMDNTVKVWDVRTHRLLQHYQLHSAAVNG 196
Query: 170 VDWSPDGQRVASGGKDKCLRI 190
+ + P G + + D L+I
Sbjct: 197 LSFHPSGNYLITASSDSTLKI 217
>gi|19913371 transducin (beta)-like 1 X-linked receptor 1 [Homo
sapiens]
Length = 514
Score = 87.0 bits (214), Expect = 9e-18
Identities = 48/154 (31%), Positives = 76/154 (49%), Gaps = 10/154 (6%)
Query: 47 QGPERLVSGSDDFTLFLWSPAEDKKPLTRMTGHQALINQVLFSPDSRIVASASFDKSIKL 106
Q S S D + + +D+ P+ GH +N + + P ++AS S D ++K+
Sbjct: 317 QSNNTFASCSTDMCIHVCKLGQDR-PIKTFQGHTNEVNAIKWDPTGNLLASCSDDMTLKI 375
Query: 107 WDGRTGKYLASLRGHVAAVYQIAWSAD---------SRLLVSGSSDSTLKVWDVKAQKLA 157
W + + L+ H +Y I WS + +L S S DST+++WDV
Sbjct: 376 WSMKQDNCVHDLQAHNKEIYTIKWSPTGPGTNNPNANLMLASASFDSTVRLWDVDRGICI 435
Query: 158 MDLPGHADEVYAVDWSPDGQRVASGGKDKCLRIW 191
L H + VY+V +SPDG+ +ASG DKC+ IW
Sbjct: 436 HTLTKHQEPVYSVAFSPDGRYLASGSFDKCVHIW 469
Score = 72.4 bits (176), Expect = 2e-13
Identities = 45/143 (31%), Positives = 70/143 (48%), Gaps = 11/143 (7%)
Query: 52 LVSGSDDFTLFLWSPAEDKKPLTRMTGHQALINQVLFSPD---------SRIVASASFDK 102
L S SDD TL +WS +D + + H I + +SP + ++ASASFD
Sbjct: 364 LASCSDDMTLKIWSMKQDNC-VHDLQAHNKEIYTIKWSPTGPGTNNPNANLMLASASFDS 422
Query: 103 SIKLWDGRTGKYLASLRGHVAAVYQIAWSADSRLLVSGSSDSTLKVWDVKAQKLAMDLPG 162
+++LWD G + +L H VY +A+S D R L SGS D + +W+ + L G
Sbjct: 423 TVRLWDVDRGICIHTLTKHQEPVYSVAFSPDGRYLASGSFDKCVHIWNTQTGALVHSYRG 482
Query: 163 HADEVYAVDWSPDGQRVASGGKD 185
++ V W+ G +V + D
Sbjct: 483 -TGGIFEVCWNAAGDKVGASASD 504
Score = 62.4 bits (150), Expect = 2e-10
Identities = 34/101 (33%), Positives = 57/101 (56%), Gaps = 2/101 (1%)
Query: 52 LVSGSDDFTLFLWSPAEDKKPLTRMTGHQALINQVLFSPDSRIVASASFDKSIKLWDGRT 111
L S S D T+ LW + + +T HQ + V FSPD R +AS SFDK + +W+ +T
Sbjct: 415 LASASFDSTVRLWD-VDRGICIHTLTKHQEPVYSVAFSPDGRYLASGSFDKCVHIWNTQT 473
Query: 112 GKYLASLRGHVAAVYQIAWSADSRLLVSGSSDSTLKVWDVK 152
G + S RG ++++ W+A + + +SD ++ V D++
Sbjct: 474 GALVHSYRG-TGGIFEVCWNAAGDKVGASASDGSVCVLDLR 513
Score = 62.0 bits (149), Expect = 3e-10
Identities = 45/190 (23%), Positives = 69/190 (36%), Gaps = 52/190 (27%)
Query: 52 LVSGSDDFTLFLWSPAEDKKPLTRMTGHQALINQVLFSPDSRIVASASFDKSIKLWDGRT 111
L +GS D +W+ +D + + H+ I + ++ + SA DK+ +WD T
Sbjct: 240 LATGSYDGFARIWT--KDGNLASTLGQHKGPIFALKWNKKGNFILSAGVDKTTIIWDAHT 297
Query: 112 GKY-----------------------------------------LASLRGHVAAVYQIAW 130
G+ + + +GH V I W
Sbjct: 298 GEAKQQFPFHSAPALDVDWQSNNTFASCSTDMCIHVCKLGQDRPIKTFQGHTNEVNAIKW 357
Query: 131 SADSRLLVSGSSDSTLKVWDVKAQKLAMDLPGHADEVYAVDWSPDGQ---------RVAS 181
LL S S D TLK+W +K DL H E+Y + WSP G +AS
Sbjct: 358 DPTGNLLASCSDDMTLKIWSMKQDNCVHDLQAHNKEIYTIKWSPTGPGTNNPNANLMLAS 417
Query: 182 GGKDKCLRIW 191
D +R+W
Sbjct: 418 ASFDSTVRLW 427
Score = 55.1 bits (131), Expect = 4e-08
Identities = 30/91 (32%), Positives = 47/91 (51%), Gaps = 16/91 (17%)
Query: 118 LRGHVAAVYQIAWSADSRLLVSGSSDSTLKVWDVKAQKLA---------------MDLPG 162
LRGH + V+ AW+ S LL SGS DST ++W++ + D+P
Sbjct: 165 LRGHESEVFICAWNPVSDLLASGSGDSTARIWNLSENSTSGSTQLVLRHCIREGGQDVPS 224
Query: 163 HADEVYAVDWSPDGQRVASGGKDKCLRIWRR 193
+ D V ++DW+ +G +A+G D RIW +
Sbjct: 225 NKD-VTSLDWNSEGTLLATGSYDGFARIWTK 254
Score = 53.5 bits (127), Expect = 1e-07
Identities = 44/194 (22%), Positives = 72/194 (37%), Gaps = 55/194 (28%)
Query: 52 LVSGSDDFTLFLWSPAEDK---------KPLTRMTGHQALINQVLFSPD----SRIVASA 98
L SGS D T +W+ +E+ + R G N+ + S D ++A+
Sbjct: 184 LASGSGDSTARIWNLSENSTSGSTQLVLRHCIREGGQDVPSNKDVTSLDWNSEGTLLATG 243
Query: 99 SFDKSIKLWDGRTGKYLASLRGHVAAVYQIAWSADSRLLVSGSSDSTLKVWD-------- 150
S+D ++W + G ++L H ++ + W+ ++S D T +WD
Sbjct: 244 SYDGFARIWT-KDGNLASTLGQHKGPIFALKWNKKGNFILSAGVDKTTIIWDAHTGEAKQ 302
Query: 151 ----------------------------VKAQKLAMDLP-----GHADEVYAVDWSPDGQ 177
+ KL D P GH +EV A+ W P G
Sbjct: 303 QFPFHSAPALDVDWQSNNTFASCSTDMCIHVCKLGQDRPIKTFQGHTNEVNAIKWDPTGN 362
Query: 178 RVASGGKDKCLRIW 191
+AS D L+IW
Sbjct: 363 LLASCSDDMTLKIW 376
Score = 53.1 bits (126), Expect = 1e-07
Identities = 34/130 (26%), Positives = 60/130 (46%), Gaps = 15/130 (11%)
Query: 76 MTGHQALINQVLFSPDSRIVASASFDKSIKLWD----GRTGKYLASLRGHVAA------- 124
+ GH++ + ++P S ++AS S D + ++W+ +G LR +
Sbjct: 165 LRGHESEVFICAWNPVSDLLASGSGDSTARIWNLSENSTSGSTQLVLRHCIREGGQDVPS 224
Query: 125 ---VYQIAWSADSRLLVSGSSDSTLKVWDVKAQKLAMDLPGHADEVYAVDWSPDGQRVAS 181
V + W+++ LL +GS D ++W K LA L H ++A+ W+ G + S
Sbjct: 225 NKDVTSLDWNSEGTLLATGSYDGFARIW-TKDGNLASTLGQHKGPIFALKWNKKGNFILS 283
Query: 182 GGKDKCLRIW 191
G DK IW
Sbjct: 284 AGVDKTTIIW 293
Score = 33.9 bits (76), Expect = 0.088
Identities = 15/35 (42%), Positives = 19/35 (54%)
Query: 157 AMDLPGHADEVYAVDWSPDGQRVASGGKDKCLRIW 191
A+ L GH EV+ W+P +ASG D RIW
Sbjct: 162 AVVLRGHESEVFICAWNPVSDLLASGSGDSTARIW 196
>gi|4505731 peroxisomal biogenesis factor 7 [Homo sapiens]
Length = 323
Score = 85.5 bits (210), Expect = 3e-17
Identities = 49/144 (34%), Positives = 74/144 (51%), Gaps = 4/144 (2%)
Query: 52 LVSGSDDFTLFLWSPAEDKKPLTRMTGHQALINQVLFSPD--SRIVASASFDKSIKLWDG 109
L++ S D +L LW A+ PL H + V +S ++V S S+D+++KLWD
Sbjct: 83 LITCSGDGSLQLWDTAKAAGPLQVYKEHAQEVYSVDWSQTRGEQLVVSGSWDQTVKLWDP 142
Query: 110 RTGKYLASLRGHVAAVYQIAWSAD-SRLLVSGSSDSTLKVWDVKAQKLAMDLPGHADEVY 168
GK L + RGH + +Y WS S S D TL++WDVKA + + +P H E+
Sbjct: 143 TVGKSLCTFRGHESIIYSTIWSPHIPGCFASASGDQTLRIWDVKAAGVRIVIPAHQAEIL 202
Query: 169 AVDWSPDGQR-VASGGKDKCLRIW 191
+ DW + + +G D LR W
Sbjct: 203 SCDWCKYNENLLVTGAVDCSLRGW 226
Score = 74.3 bits (181), Expect = 6e-14
Identities = 54/170 (31%), Positives = 86/170 (50%), Gaps = 7/170 (4%)
Query: 28 GSLQELKERALSRYNLVRGQ--GPERLVSGSDDFTLFLWSPAEDKKPLTRMTGHQALINQ 85
G LQ KE A Y++ Q G + +VSGS D T+ LW P K L GH+++I
Sbjct: 102 GPLQVYKEHAQEVYSVDWSQTRGEQLVVSGSWDQTVKLWDPTVGKS-LCTFRGHESIIYS 160
Query: 86 VLFSPD-SRIVASASFDKSIKLWDGRTGKYLASLRGHVAAVYQIAW-SADSRLLVSGSSD 143
++SP ASAS D+++++WD + + H A + W + LLV+G+ D
Sbjct: 161 TIWSPHIPGCFASASGDQTLRIWDVKAAGVRIVIPAHQAEILSCDWCKYNENLLVTGAVD 220
Query: 144 STLKVWDVK-AQKLAMDLPGHADEVYAVDWSP-DGQRVASGGKDKCLRIW 191
+L+ WD++ ++ +L GH + V +SP +AS D +R W
Sbjct: 221 CSLRGWDLRNVRQPVFELLGHTYAIRRVKFSPFHASVLASCSYDFTVRFW 270
Score = 46.2 bits (108), Expect = 2e-05
Identities = 29/102 (28%), Positives = 54/102 (52%), Gaps = 3/102 (2%)
Query: 52 LVSGSDDFTLFLWSPAEDKKPLTRMTGHQALINQVLFSP-DSRIVASASFDKSIKLWD-G 109
LV+G+ D +L W ++P+ + GH I +V FSP + ++AS S+D +++ W+
Sbjct: 214 LVTGAVDCSLRGWDLRNVRQPVFELLGHTYAIRRVKFSPFHASVLASCSYDFTVRFWNFS 273
Query: 110 RTGKYLASLRGHVAAVYQIAWSADSRLLVSGSS-DSTLKVWD 150
+ L ++ H + +S S V+ S D T+K++D
Sbjct: 274 KPDSLLETVEHHTEFTCGLDFSLQSPTQVADCSWDETIKIYD 315
>gi|213021190 transducin beta-like 1X isoform b [Homo sapiens]
Length = 526
Score = 85.5 bits (210), Expect = 3e-17
Identities = 42/130 (32%), Positives = 69/130 (53%), Gaps = 9/130 (6%)
Query: 71 KPLTRMTGHQALINQVLFSPDSRIVASASFDKSIKLWDGRTGKYLASLRGHVAAVYQIAW 130
+P+ GH +N + + P ++AS S D ++K+W + + L+ H +Y I W
Sbjct: 352 RPVKTFQGHTNEVNAIKWDPSGMLLASCSDDMTLKIWSMKQEVCIHDLQAHNKEIYTIKW 411
Query: 131 SA---------DSRLLVSGSSDSTLKVWDVKAQKLAMDLPGHADEVYAVDWSPDGQRVAS 181
S + +L S S DST+++WD++ L H + VY+V +SPDG+ +AS
Sbjct: 412 SPTGPATSNPNSNIMLASASFDSTVRLWDIERGVCTHTLTKHQEPVYSVAFSPDGKYLAS 471
Query: 182 GGKDKCLRIW 191
G DKC+ IW
Sbjct: 472 GSFDKCVHIW 481
Score = 69.7 bits (169), Expect = 1e-12
Identities = 43/143 (30%), Positives = 70/143 (48%), Gaps = 11/143 (7%)
Query: 52 LVSGSDDFTLFLWSPAEDKKPLTRMTGHQALINQVLFSP---------DSRIVASASFDK 102
L S SDD TL +WS ++ + + H I + +SP + ++ASASFD
Sbjct: 376 LASCSDDMTLKIWSMKQEVC-IHDLQAHNKEIYTIKWSPTGPATSNPNSNIMLASASFDS 434
Query: 103 SIKLWDGRTGKYLASLRGHVAAVYQIAWSADSRLLVSGSSDSTLKVWDVKAQKLAMDLPG 162
+++LWD G +L H VY +A+S D + L SGS D + +W+ ++ L G
Sbjct: 435 TVRLWDIERGVCTHTLTKHQEPVYSVAFSPDGKYLASGSFDKCVHIWNTQSGNLVHSYRG 494
Query: 163 HADEVYAVDWSPDGQRVASGGKD 185
++ V W+ G +V + D
Sbjct: 495 -TGGIFEVCWNARGDKVGASASD 516
Score = 62.0 bits (149), Expect = 3e-10
Identities = 46/190 (24%), Positives = 70/190 (36%), Gaps = 52/190 (27%)
Query: 52 LVSGSDDFTLFLWSPAEDKKPLTRMTGHQALINQVLFSPDSRIVASASFDKSIKLWDGRT 111
L +GS D +W+ ED + + H+ I + ++ + SA DK+ +WD T
Sbjct: 252 LATGSYDGFARIWT--EDGNLASTLGQHKGPIFALKWNRKGNYILSAGVDKTTIIWDAHT 309
Query: 112 GKY-----------------------------------------LASLRGHVAAVYQIAW 130
G+ + + +GH V I W
Sbjct: 310 GEAKQQFPFHSAPALDVDWQNNTTFASCSTDMCIHVCRLGCDRPVKTFQGHTNEVNAIKW 369
Query: 131 SADSRLLVSGSSDSTLKVWDVKAQKLAMDLPGHADEVYAVDWSPDGQ---------RVAS 181
LL S S D TLK+W +K + DL H E+Y + WSP G +AS
Sbjct: 370 DPSGMLLASCSDDMTLKIWSMKQEVCIHDLQAHNKEIYTIKWSPTGPATSNPNSNIMLAS 429
Query: 182 GGKDKCLRIW 191
D +R+W
Sbjct: 430 ASFDSTVRLW 439
Score = 60.1 bits (144), Expect = 1e-09
Identities = 33/101 (32%), Positives = 56/101 (55%), Gaps = 2/101 (1%)
Query: 52 LVSGSDDFTLFLWSPAEDKKPLTRMTGHQALINQVLFSPDSRIVASASFDKSIKLWDGRT 111
L S S D T+ LW T +T HQ + V FSPD + +AS SFDK + +W+ ++
Sbjct: 427 LASASFDSTVRLWDIERGVCTHT-LTKHQEPVYSVAFSPDGKYLASGSFDKCVHIWNTQS 485
Query: 112 GKYLASLRGHVAAVYQIAWSADSRLLVSGSSDSTLKVWDVK 152
G + S RG ++++ W+A + + +SD ++ V D++
Sbjct: 486 GNLVHSYRG-TGGIFEVCWNARGDKVGASASDGSVCVLDLR 525
Score = 54.7 bits (130), Expect = 5e-08
Identities = 37/154 (24%), Positives = 63/154 (40%), Gaps = 15/154 (9%)
Query: 52 LVSGSDDFTLFLWSPAEDK---------KPLTRMTGHQALINQVLFSPD----SRIVASA 98
L SGS D T +W+ E+ + R GH N+ + S D ++A+
Sbjct: 196 LASGSGDSTARIWNLNENSNGGSTQLVLRHCIREGGHDVPSNKDVTSLDWNTNGTLLATG 255
Query: 99 SFDKSIKLWDGRTGKYLASLRGHVAAVYQIAWSADSRLLVSGSSDSTLKVWDVKAQKLAM 158
S+D ++W G ++L H ++ + W+ ++S D T +WD +
Sbjct: 256 SYDGFARIWT-EDGNLASTLGQHKGPIFALKWNRKGNYILSAGVDKTTIIWDAHTGEAKQ 314
Query: 159 DLPGHADEVYAVDWSPDGQRVASGGKDKCLRIWR 192
P H+ VDW + AS D C+ + R
Sbjct: 315 QFPFHSAPALDVDWQ-NNTTFASCSTDMCIHVCR 347
Score = 53.1 bits (126), Expect = 1e-07
Identities = 31/89 (34%), Positives = 49/89 (55%), Gaps = 16/89 (17%)
Query: 118 LRGHVAAVYQIAWSADSRLLVSGSSDSTLKVWDVK------AQKLAM---------DLPG 162
LRGH + V+ AW+ S LL SGS DST ++W++ + +L + D+P
Sbjct: 177 LRGHESEVFICAWNPVSDLLASGSGDSTARIWNLNENSNGGSTQLVLRHCIREGGHDVPS 236
Query: 163 HADEVYAVDWSPDGQRVASGGKDKCLRIW 191
+ D V ++DW+ +G +A+G D RIW
Sbjct: 237 NKD-VTSLDWNTNGTLLATGSYDGFARIW 264
Score = 52.0 bits (123), Expect = 3e-07
Identities = 36/132 (27%), Positives = 60/132 (45%), Gaps = 15/132 (11%)
Query: 74 TRMTGHQALINQVLFSPDSRIVASASFDKSIKLW----DGRTGKYLASLR------GHVA 123
T + GH++ + ++P S ++AS S D + ++W + G LR GH
Sbjct: 175 TVLRGHESEVFICAWNPVSDLLASGSGDSTARIWNLNENSNGGSTQLVLRHCIREGGHDV 234
Query: 124 A----VYQIAWSADSRLLVSGSSDSTLKVWDVKAQKLAMDLPGHADEVYAVDWSPDGQRV 179
V + W+ + LL +GS D ++W + LA L H ++A+ W+ G +
Sbjct: 235 PSNKDVTSLDWNTNGTLLATGSYDGFARIW-TEDGNLASTLGQHKGPIFALKWNRKGNYI 293
Query: 180 ASGGKDKCLRIW 191
S G DK IW
Sbjct: 294 LSAGVDKTTIIW 305
>gi|213021188 transducin beta-like 1X isoform b [Homo sapiens]
Length = 526
Score = 85.5 bits (210), Expect = 3e-17
Identities = 42/130 (32%), Positives = 69/130 (53%), Gaps = 9/130 (6%)
Query: 71 KPLTRMTGHQALINQVLFSPDSRIVASASFDKSIKLWDGRTGKYLASLRGHVAAVYQIAW 130
+P+ GH +N + + P ++AS S D ++K+W + + L+ H +Y I W
Sbjct: 352 RPVKTFQGHTNEVNAIKWDPSGMLLASCSDDMTLKIWSMKQEVCIHDLQAHNKEIYTIKW 411
Query: 131 SA---------DSRLLVSGSSDSTLKVWDVKAQKLAMDLPGHADEVYAVDWSPDGQRVAS 181
S + +L S S DST+++WD++ L H + VY+V +SPDG+ +AS
Sbjct: 412 SPTGPATSNPNSNIMLASASFDSTVRLWDIERGVCTHTLTKHQEPVYSVAFSPDGKYLAS 471
Query: 182 GGKDKCLRIW 191
G DKC+ IW
Sbjct: 472 GSFDKCVHIW 481
Score = 69.7 bits (169), Expect = 1e-12
Identities = 43/143 (30%), Positives = 70/143 (48%), Gaps = 11/143 (7%)
Query: 52 LVSGSDDFTLFLWSPAEDKKPLTRMTGHQALINQVLFSP---------DSRIVASASFDK 102
L S SDD TL +WS ++ + + H I + +SP + ++ASASFD
Sbjct: 376 LASCSDDMTLKIWSMKQEVC-IHDLQAHNKEIYTIKWSPTGPATSNPNSNIMLASASFDS 434
Query: 103 SIKLWDGRTGKYLASLRGHVAAVYQIAWSADSRLLVSGSSDSTLKVWDVKAQKLAMDLPG 162
+++LWD G +L H VY +A+S D + L SGS D + +W+ ++ L G
Sbjct: 435 TVRLWDIERGVCTHTLTKHQEPVYSVAFSPDGKYLASGSFDKCVHIWNTQSGNLVHSYRG 494
Query: 163 HADEVYAVDWSPDGQRVASGGKD 185
++ V W+ G +V + D
Sbjct: 495 -TGGIFEVCWNARGDKVGASASD 516
Score = 62.0 bits (149), Expect = 3e-10
Identities = 46/190 (24%), Positives = 70/190 (36%), Gaps = 52/190 (27%)
Query: 52 LVSGSDDFTLFLWSPAEDKKPLTRMTGHQALINQVLFSPDSRIVASASFDKSIKLWDGRT 111
L +GS D +W+ ED + + H+ I + ++ + SA DK+ +WD T
Sbjct: 252 LATGSYDGFARIWT--EDGNLASTLGQHKGPIFALKWNRKGNYILSAGVDKTTIIWDAHT 309
Query: 112 GKY-----------------------------------------LASLRGHVAAVYQIAW 130
G+ + + +GH V I W
Sbjct: 310 GEAKQQFPFHSAPALDVDWQNNTTFASCSTDMCIHVCRLGCDRPVKTFQGHTNEVNAIKW 369
Query: 131 SADSRLLVSGSSDSTLKVWDVKAQKLAMDLPGHADEVYAVDWSPDGQ---------RVAS 181
LL S S D TLK+W +K + DL H E+Y + WSP G +AS
Sbjct: 370 DPSGMLLASCSDDMTLKIWSMKQEVCIHDLQAHNKEIYTIKWSPTGPATSNPNSNIMLAS 429
Query: 182 GGKDKCLRIW 191
D +R+W
Sbjct: 430 ASFDSTVRLW 439
Score = 60.1 bits (144), Expect = 1e-09
Identities = 33/101 (32%), Positives = 56/101 (55%), Gaps = 2/101 (1%)
Query: 52 LVSGSDDFTLFLWSPAEDKKPLTRMTGHQALINQVLFSPDSRIVASASFDKSIKLWDGRT 111
L S S D T+ LW T +T HQ + V FSPD + +AS SFDK + +W+ ++
Sbjct: 427 LASASFDSTVRLWDIERGVCTHT-LTKHQEPVYSVAFSPDGKYLASGSFDKCVHIWNTQS 485
Query: 112 GKYLASLRGHVAAVYQIAWSADSRLLVSGSSDSTLKVWDVK 152
G + S RG ++++ W+A + + +SD ++ V D++
Sbjct: 486 GNLVHSYRG-TGGIFEVCWNARGDKVGASASDGSVCVLDLR 525
Score = 54.7 bits (130), Expect = 5e-08
Identities = 37/154 (24%), Positives = 63/154 (40%), Gaps = 15/154 (9%)
Query: 52 LVSGSDDFTLFLWSPAEDK---------KPLTRMTGHQALINQVLFSPD----SRIVASA 98
L SGS D T +W+ E+ + R GH N+ + S D ++A+
Sbjct: 196 LASGSGDSTARIWNLNENSNGGSTQLVLRHCIREGGHDVPSNKDVTSLDWNTNGTLLATG 255
Query: 99 SFDKSIKLWDGRTGKYLASLRGHVAAVYQIAWSADSRLLVSGSSDSTLKVWDVKAQKLAM 158
S+D ++W G ++L H ++ + W+ ++S D T +WD +
Sbjct: 256 SYDGFARIWT-EDGNLASTLGQHKGPIFALKWNRKGNYILSAGVDKTTIIWDAHTGEAKQ 314
Query: 159 DLPGHADEVYAVDWSPDGQRVASGGKDKCLRIWR 192
P H+ VDW + AS D C+ + R
Sbjct: 315 QFPFHSAPALDVDWQ-NNTTFASCSTDMCIHVCR 347
Score = 53.1 bits (126), Expect = 1e-07
Identities = 31/89 (34%), Positives = 49/89 (55%), Gaps = 16/89 (17%)
Query: 118 LRGHVAAVYQIAWSADSRLLVSGSSDSTLKVWDVK------AQKLAM---------DLPG 162
LRGH + V+ AW+ S LL SGS DST ++W++ + +L + D+P
Sbjct: 177 LRGHESEVFICAWNPVSDLLASGSGDSTARIWNLNENSNGGSTQLVLRHCIREGGHDVPS 236
Query: 163 HADEVYAVDWSPDGQRVASGGKDKCLRIW 191
+ D V ++DW+ +G +A+G D RIW
Sbjct: 237 NKD-VTSLDWNTNGTLLATGSYDGFARIW 264
Score = 52.0 bits (123), Expect = 3e-07
Identities = 36/132 (27%), Positives = 60/132 (45%), Gaps = 15/132 (11%)
Query: 74 TRMTGHQALINQVLFSPDSRIVASASFDKSIKLW----DGRTGKYLASLR------GHVA 123
T + GH++ + ++P S ++AS S D + ++W + G LR GH
Sbjct: 175 TVLRGHESEVFICAWNPVSDLLASGSGDSTARIWNLNENSNGGSTQLVLRHCIREGGHDV 234
Query: 124 A----VYQIAWSADSRLLVSGSSDSTLKVWDVKAQKLAMDLPGHADEVYAVDWSPDGQRV 179
V + W+ + LL +GS D ++W + LA L H ++A+ W+ G +
Sbjct: 235 PSNKDVTSLDWNTNGTLLATGSYDGFARIW-TEDGNLASTLGQHKGPIFALKWNRKGNYI 293
Query: 180 ASGGKDKCLRIW 191
S G DK IW
Sbjct: 294 LSAGVDKTTIIW 305
>gi|213021186 transducin beta-like 1X isoform a [Homo sapiens]
Length = 577
Score = 85.5 bits (210), Expect = 3e-17
Identities = 42/130 (32%), Positives = 69/130 (53%), Gaps = 9/130 (6%)
Query: 71 KPLTRMTGHQALINQVLFSPDSRIVASASFDKSIKLWDGRTGKYLASLRGHVAAVYQIAW 130
+P+ GH +N + + P ++AS S D ++K+W + + L+ H +Y I W
Sbjct: 403 RPVKTFQGHTNEVNAIKWDPSGMLLASCSDDMTLKIWSMKQEVCIHDLQAHNKEIYTIKW 462
Query: 131 SA---------DSRLLVSGSSDSTLKVWDVKAQKLAMDLPGHADEVYAVDWSPDGQRVAS 181
S + +L S S DST+++WD++ L H + VY+V +SPDG+ +AS
Sbjct: 463 SPTGPATSNPNSNIMLASASFDSTVRLWDIERGVCTHTLTKHQEPVYSVAFSPDGKYLAS 522
Query: 182 GGKDKCLRIW 191
G DKC+ IW
Sbjct: 523 GSFDKCVHIW 532
Score = 69.7 bits (169), Expect = 1e-12
Identities = 43/143 (30%), Positives = 70/143 (48%), Gaps = 11/143 (7%)
Query: 52 LVSGSDDFTLFLWSPAEDKKPLTRMTGHQALINQVLFSP---------DSRIVASASFDK 102
L S SDD TL +WS ++ + + H I + +SP + ++ASASFD
Sbjct: 427 LASCSDDMTLKIWSMKQEVC-IHDLQAHNKEIYTIKWSPTGPATSNPNSNIMLASASFDS 485
Query: 103 SIKLWDGRTGKYLASLRGHVAAVYQIAWSADSRLLVSGSSDSTLKVWDVKAQKLAMDLPG 162
+++LWD G +L H VY +A+S D + L SGS D + +W+ ++ L G
Sbjct: 486 TVRLWDIERGVCTHTLTKHQEPVYSVAFSPDGKYLASGSFDKCVHIWNTQSGNLVHSYRG 545
Query: 163 HADEVYAVDWSPDGQRVASGGKD 185
++ V W+ G +V + D
Sbjct: 546 -TGGIFEVCWNARGDKVGASASD 567
Score = 62.0 bits (149), Expect = 3e-10
Identities = 46/190 (24%), Positives = 70/190 (36%), Gaps = 52/190 (27%)
Query: 52 LVSGSDDFTLFLWSPAEDKKPLTRMTGHQALINQVLFSPDSRIVASASFDKSIKLWDGRT 111
L +GS D +W+ ED + + H+ I + ++ + SA DK+ +WD T
Sbjct: 303 LATGSYDGFARIWT--EDGNLASTLGQHKGPIFALKWNRKGNYILSAGVDKTTIIWDAHT 360
Query: 112 GKY-----------------------------------------LASLRGHVAAVYQIAW 130
G+ + + +GH V I W
Sbjct: 361 GEAKQQFPFHSAPALDVDWQNNTTFASCSTDMCIHVCRLGCDRPVKTFQGHTNEVNAIKW 420
Query: 131 SADSRLLVSGSSDSTLKVWDVKAQKLAMDLPGHADEVYAVDWSPDGQ---------RVAS 181
LL S S D TLK+W +K + DL H E+Y + WSP G +AS
Sbjct: 421 DPSGMLLASCSDDMTLKIWSMKQEVCIHDLQAHNKEIYTIKWSPTGPATSNPNSNIMLAS 480
Query: 182 GGKDKCLRIW 191
D +R+W
Sbjct: 481 ASFDSTVRLW 490
Score = 60.1 bits (144), Expect = 1e-09
Identities = 33/101 (32%), Positives = 56/101 (55%), Gaps = 2/101 (1%)
Query: 52 LVSGSDDFTLFLWSPAEDKKPLTRMTGHQALINQVLFSPDSRIVASASFDKSIKLWDGRT 111
L S S D T+ LW T +T HQ + V FSPD + +AS SFDK + +W+ ++
Sbjct: 478 LASASFDSTVRLWDIERGVCTHT-LTKHQEPVYSVAFSPDGKYLASGSFDKCVHIWNTQS 536
Query: 112 GKYLASLRGHVAAVYQIAWSADSRLLVSGSSDSTLKVWDVK 152
G + S RG ++++ W+A + + +SD ++ V D++
Sbjct: 537 GNLVHSYRG-TGGIFEVCWNARGDKVGASASDGSVCVLDLR 576
Score = 54.7 bits (130), Expect = 5e-08
Identities = 37/154 (24%), Positives = 63/154 (40%), Gaps = 15/154 (9%)
Query: 52 LVSGSDDFTLFLWSPAEDK---------KPLTRMTGHQALINQVLFSPD----SRIVASA 98
L SGS D T +W+ E+ + R GH N+ + S D ++A+
Sbjct: 247 LASGSGDSTARIWNLNENSNGGSTQLVLRHCIREGGHDVPSNKDVTSLDWNTNGTLLATG 306
Query: 99 SFDKSIKLWDGRTGKYLASLRGHVAAVYQIAWSADSRLLVSGSSDSTLKVWDVKAQKLAM 158
S+D ++W G ++L H ++ + W+ ++S D T +WD +
Sbjct: 307 SYDGFARIWT-EDGNLASTLGQHKGPIFALKWNRKGNYILSAGVDKTTIIWDAHTGEAKQ 365
Query: 159 DLPGHADEVYAVDWSPDGQRVASGGKDKCLRIWR 192
P H+ VDW + AS D C+ + R
Sbjct: 366 QFPFHSAPALDVDWQ-NNTTFASCSTDMCIHVCR 398
Score = 53.1 bits (126), Expect = 1e-07
Identities = 31/89 (34%), Positives = 49/89 (55%), Gaps = 16/89 (17%)
Query: 118 LRGHVAAVYQIAWSADSRLLVSGSSDSTLKVWDVK------AQKLAM---------DLPG 162
LRGH + V+ AW+ S LL SGS DST ++W++ + +L + D+P
Sbjct: 228 LRGHESEVFICAWNPVSDLLASGSGDSTARIWNLNENSNGGSTQLVLRHCIREGGHDVPS 287
Query: 163 HADEVYAVDWSPDGQRVASGGKDKCLRIW 191
+ D V ++DW+ +G +A+G D RIW
Sbjct: 288 NKD-VTSLDWNTNGTLLATGSYDGFARIW 315
Score = 52.0 bits (123), Expect = 3e-07
Identities = 36/132 (27%), Positives = 60/132 (45%), Gaps = 15/132 (11%)
Query: 74 TRMTGHQALINQVLFSPDSRIVASASFDKSIKLW----DGRTGKYLASLR------GHVA 123
T + GH++ + ++P S ++AS S D + ++W + G LR GH
Sbjct: 226 TVLRGHESEVFICAWNPVSDLLASGSGDSTARIWNLNENSNGGSTQLVLRHCIREGGHDV 285
Query: 124 A----VYQIAWSADSRLLVSGSSDSTLKVWDVKAQKLAMDLPGHADEVYAVDWSPDGQRV 179
V + W+ + LL +GS D ++W + LA L H ++A+ W+ G +
Sbjct: 286 PSNKDVTSLDWNTNGTLLATGSYDGFARIW-TEDGNLASTLGQHKGPIFALKWNRKGNYI 344
Query: 180 ASGGKDKCLRIW 191
S G DK IW
Sbjct: 345 LSAGVDKTTIIW 356
>gi|5032159 transducin beta-like 1X isoform a [Homo sapiens]
Length = 577
Score = 85.5 bits (210), Expect = 3e-17
Identities = 42/130 (32%), Positives = 69/130 (53%), Gaps = 9/130 (6%)
Query: 71 KPLTRMTGHQALINQVLFSPDSRIVASASFDKSIKLWDGRTGKYLASLRGHVAAVYQIAW 130
+P+ GH +N + + P ++AS S D ++K+W + + L+ H +Y I W
Sbjct: 403 RPVKTFQGHTNEVNAIKWDPSGMLLASCSDDMTLKIWSMKQEVCIHDLQAHNKEIYTIKW 462
Query: 131 SA---------DSRLLVSGSSDSTLKVWDVKAQKLAMDLPGHADEVYAVDWSPDGQRVAS 181
S + +L S S DST+++WD++ L H + VY+V +SPDG+ +AS
Sbjct: 463 SPTGPATSNPNSNIMLASASFDSTVRLWDIERGVCTHTLTKHQEPVYSVAFSPDGKYLAS 522
Query: 182 GGKDKCLRIW 191
G DKC+ IW
Sbjct: 523 GSFDKCVHIW 532
Score = 69.7 bits (169), Expect = 1e-12
Identities = 43/143 (30%), Positives = 70/143 (48%), Gaps = 11/143 (7%)
Query: 52 LVSGSDDFTLFLWSPAEDKKPLTRMTGHQALINQVLFSP---------DSRIVASASFDK 102
L S SDD TL +WS ++ + + H I + +SP + ++ASASFD
Sbjct: 427 LASCSDDMTLKIWSMKQEVC-IHDLQAHNKEIYTIKWSPTGPATSNPNSNIMLASASFDS 485
Query: 103 SIKLWDGRTGKYLASLRGHVAAVYQIAWSADSRLLVSGSSDSTLKVWDVKAQKLAMDLPG 162
+++LWD G +L H VY +A+S D + L SGS D + +W+ ++ L G
Sbjct: 486 TVRLWDIERGVCTHTLTKHQEPVYSVAFSPDGKYLASGSFDKCVHIWNTQSGNLVHSYRG 545
Query: 163 HADEVYAVDWSPDGQRVASGGKD 185
++ V W+ G +V + D
Sbjct: 546 -TGGIFEVCWNARGDKVGASASD 567
Score = 62.0 bits (149), Expect = 3e-10
Identities = 46/190 (24%), Positives = 70/190 (36%), Gaps = 52/190 (27%)
Query: 52 LVSGSDDFTLFLWSPAEDKKPLTRMTGHQALINQVLFSPDSRIVASASFDKSIKLWDGRT 111
L +GS D +W+ ED + + H+ I + ++ + SA DK+ +WD T
Sbjct: 303 LATGSYDGFARIWT--EDGNLASTLGQHKGPIFALKWNRKGNYILSAGVDKTTIIWDAHT 360
Query: 112 GKY-----------------------------------------LASLRGHVAAVYQIAW 130
G+ + + +GH V I W
Sbjct: 361 GEAKQQFPFHSAPALDVDWQNNTTFASCSTDMCIHVCRLGCDRPVKTFQGHTNEVNAIKW 420
Query: 131 SADSRLLVSGSSDSTLKVWDVKAQKLAMDLPGHADEVYAVDWSPDGQ---------RVAS 181
LL S S D TLK+W +K + DL H E+Y + WSP G +AS
Sbjct: 421 DPSGMLLASCSDDMTLKIWSMKQEVCIHDLQAHNKEIYTIKWSPTGPATSNPNSNIMLAS 480
Query: 182 GGKDKCLRIW 191
D +R+W
Sbjct: 481 ASFDSTVRLW 490
Score = 60.1 bits (144), Expect = 1e-09
Identities = 33/101 (32%), Positives = 56/101 (55%), Gaps = 2/101 (1%)
Query: 52 LVSGSDDFTLFLWSPAEDKKPLTRMTGHQALINQVLFSPDSRIVASASFDKSIKLWDGRT 111
L S S D T+ LW T +T HQ + V FSPD + +AS SFDK + +W+ ++
Sbjct: 478 LASASFDSTVRLWDIERGVCTHT-LTKHQEPVYSVAFSPDGKYLASGSFDKCVHIWNTQS 536
Query: 112 GKYLASLRGHVAAVYQIAWSADSRLLVSGSSDSTLKVWDVK 152
G + S RG ++++ W+A + + +SD ++ V D++
Sbjct: 537 GNLVHSYRG-TGGIFEVCWNARGDKVGASASDGSVCVLDLR 576
Score = 54.7 bits (130), Expect = 5e-08
Identities = 37/154 (24%), Positives = 63/154 (40%), Gaps = 15/154 (9%)
Query: 52 LVSGSDDFTLFLWSPAEDK---------KPLTRMTGHQALINQVLFSPD----SRIVASA 98
L SGS D T +W+ E+ + R GH N+ + S D ++A+
Sbjct: 247 LASGSGDSTARIWNLNENSNGGSTQLVLRHCIREGGHDVPSNKDVTSLDWNTNGTLLATG 306
Query: 99 SFDKSIKLWDGRTGKYLASLRGHVAAVYQIAWSADSRLLVSGSSDSTLKVWDVKAQKLAM 158
S+D ++W G ++L H ++ + W+ ++S D T +WD +
Sbjct: 307 SYDGFARIWT-EDGNLASTLGQHKGPIFALKWNRKGNYILSAGVDKTTIIWDAHTGEAKQ 365
Query: 159 DLPGHADEVYAVDWSPDGQRVASGGKDKCLRIWR 192
P H+ VDW + AS D C+ + R
Sbjct: 366 QFPFHSAPALDVDWQ-NNTTFASCSTDMCIHVCR 398
Score = 53.1 bits (126), Expect = 1e-07
Identities = 31/89 (34%), Positives = 49/89 (55%), Gaps = 16/89 (17%)
Query: 118 LRGHVAAVYQIAWSADSRLLVSGSSDSTLKVWDVK------AQKLAM---------DLPG 162
LRGH + V+ AW+ S LL SGS DST ++W++ + +L + D+P
Sbjct: 228 LRGHESEVFICAWNPVSDLLASGSGDSTARIWNLNENSNGGSTQLVLRHCIREGGHDVPS 287
Query: 163 HADEVYAVDWSPDGQRVASGGKDKCLRIW 191
+ D V ++DW+ +G +A+G D RIW
Sbjct: 288 NKD-VTSLDWNTNGTLLATGSYDGFARIW 315
Score = 52.0 bits (123), Expect = 3e-07
Identities = 36/132 (27%), Positives = 60/132 (45%), Gaps = 15/132 (11%)
Query: 74 TRMTGHQALINQVLFSPDSRIVASASFDKSIKLW----DGRTGKYLASLR------GHVA 123
T + GH++ + ++P S ++AS S D + ++W + G LR GH
Sbjct: 226 TVLRGHESEVFICAWNPVSDLLASGSGDSTARIWNLNENSNGGSTQLVLRHCIREGGHDV 285
Query: 124 A----VYQIAWSADSRLLVSGSSDSTLKVWDVKAQKLAMDLPGHADEVYAVDWSPDGQRV 179
V + W+ + LL +GS D ++W + LA L H ++A+ W+ G +
Sbjct: 286 PSNKDVTSLDWNTNGTLLATGSYDGFARIW-TEDGNLASTLGQHKGPIFALKWNRKGNYI 344
Query: 180 ASGGKDKCLRIW 191
S G DK IW
Sbjct: 345 LSAGVDKTTIIW 356
>gi|13376840 WD repeat domain 61 [Homo sapiens]
Length = 305
Score = 84.3 bits (207), Expect = 6e-17
Identities = 52/193 (26%), Positives = 94/193 (48%), Gaps = 3/193 (1%)
Query: 1 MALSTDYALRTGAFEPAEASVNPQDLQGSLQ--ELKERALSRYNLVRGQGPERLVSGSDD 58
+++ + L A +A + DL+ Q + + + L + L +G+
Sbjct: 68 VSVDISHTLPIAASSSLDAHIRLWDLENGKQIKSIDAGPVDAWTLAFSPDSQYLATGTHV 127
Query: 59 FTLFLWSPAEDKKPLTRMTGHQALINQVLFSPDSRIVASASFDKSIKLWDGRTGKYLASL 118
+ ++ KK + T + +++ + +SPD + +AS + D I ++D TGK L +L
Sbjct: 128 GKVNIFGVESGKKEYSLDTRGKFILS-IAYSPDGKYLASGAIDGIINIFDIATGKLLHTL 186
Query: 119 RGHVAAVYQIAWSADSRLLVSGSSDSTLKVWDVKAQKLAMDLPGHADEVYAVDWSPDGQR 178
GH + + +S DS+LLV+ S D +K++DV+ LA L GHA V V + PD
Sbjct: 187 EGHAMPIRSLTFSPDSQLLVTASDDGYIKIYDVQHANLAGTLSGHASWVLNVAFCPDDTH 246
Query: 179 VASGGKDKCLRIW 191
S DK +++W
Sbjct: 247 FVSSSSDKSVKVW 259
Score = 80.5 bits (197), Expect = 8e-16
Identities = 46/140 (32%), Positives = 76/140 (54%), Gaps = 1/140 (0%)
Query: 52 LVSGSDDFTLFLWSPAEDKKPLTRMTGHQALINQVLFSPDSRIVASASFDKSIKLWDGRT 111
L SG+ D + ++ A K L + GH I + FSPDS+++ +AS D IK++D +
Sbjct: 163 LASGAIDGIINIFDIATGKL-LHTLEGHAMPIRSLTFSPDSQLLVTASDDGYIKIYDVQH 221
Query: 112 GKYLASLRGHVAAVYQIAWSADSRLLVSGSSDSTLKVWDVKAQKLAMDLPGHADEVYAVD 171
+L GH + V +A+ D VS SSD ++KVWDV + H D+V+ V
Sbjct: 222 ANLAGTLSGHASWVLNVAFCPDDTHFVSSSSDKSVKVWDVGTRTCVHTFFDHQDQVWGVK 281
Query: 172 WSPDGQRVASGGKDKCLRIW 191
++ +G ++ S G D+ + I+
Sbjct: 282 YNGNGSKIVSVGDDQEIHIY 301
Score = 68.6 bits (166), Expect = 3e-12
Identities = 42/146 (28%), Positives = 75/146 (51%), Gaps = 1/146 (0%)
Query: 47 QGPERLVSGSDDFTLFLWSPAEDKKPLT-RMTGHQALINQVLFSPDSRIVASASFDKSIK 105
+ E +V+GS D + +W +++ L + GHQ + V S I AS+S D I+
Sbjct: 30 ENSETVVTGSLDDLVKVWKWRDERLDLQWSLEGHQLGVVSVDISHTLPIAASSSLDAHIR 89
Query: 106 LWDGRTGKYLASLRGHVAAVYQIAWSADSRLLVSGSSDSTLKVWDVKAQKLAMDLPGHAD 165
LWD GK + S+ + +A+S DS+ L +G+ + ++ V++ K L
Sbjct: 90 LWDLENGKQIKSIDAGPVDAWTLAFSPDSQYLATGTHVGKVNIFGVESGKKEYSLDTRGK 149
Query: 166 EVYAVDWSPDGQRVASGGKDKCLRIW 191
+ ++ +SPDG+ +ASG D + I+
Sbjct: 150 FILSIAYSPDGKYLASGAIDGIINIF 175
Score = 48.1 bits (113), Expect = 5e-06
Identities = 31/121 (25%), Positives = 57/121 (47%), Gaps = 1/121 (0%)
Query: 30 LQELKERALSRYNLVRGQGPERLVSGSDDFTLFLWSPAEDKKPLTRMTGHQALINQVLFS 89
L L+ A+ +L + LV+ SDD + ++ T ++GH + + V F
Sbjct: 183 LHTLEGHAMPIRSLTFSPDSQLLVTASDDGYIKIYDVQHANLAGT-LSGHASWVLNVAFC 241
Query: 90 PDSRIVASASFDKSIKLWDGRTGKYLASLRGHVAAVYQIAWSADSRLLVSGSSDSTLKVW 149
PD S+S DKS+K+WD T + + H V+ + ++ + +VS D + ++
Sbjct: 242 PDDTHFVSSSSDKSVKVWDVGTRTCVHTFFDHQDQVWGVKYNGNGSKIVSVGDDQEIHIY 301
Query: 150 D 150
D
Sbjct: 302 D 302
>gi|61743926 F-box and WD repeat domain containing 7 isoform 3 [Homo
sapiens]
Length = 589
Score = 83.6 bits (205), Expect = 1e-16
Identities = 53/143 (37%), Positives = 80/143 (55%), Gaps = 11/143 (7%)
Query: 51 RLVSGSDDFTLFLWSPAEDKKPLTRMTGHQALINQVLFSPDSR--IVASASFDKSIKLWD 108
R+VSGSDD TL +WS A K L + GH + +S R I+ S S D+++K+W+
Sbjct: 275 RIVSGSDDNTLKVWS-AVTGKCLRTLVGHTGGV----WSSQMRDNIIISGSTDRTLKVWN 329
Query: 109 GRTGKYLASLRGHVAAVYQIAWSADSRLLVSGSSDSTLKVWDVKAQKLAMDLPGHADEVY 168
TG+ + +L GH + V + +VSGS D+TL+VWD++ + L GH V
Sbjct: 330 AETGECIHTLYGHTSTVR--CMHLHEKRVVSGSRDATLRVWDIETGQCLHVLMGHVAAVR 387
Query: 169 AVDWSPDGQRVASGGKDKCLRIW 191
V + DG+RV SG D +++W
Sbjct: 388 CVQY--DGRRVVSGAYDFMVKVW 408
Score = 83.6 bits (205), Expect = 1e-16
Identities = 51/140 (36%), Positives = 82/140 (58%), Gaps = 7/140 (5%)
Query: 52 LVSGSDDFTLFLWSPAEDKKPLTRMTGHQALINQVLFSPDSRIVASASFDKSIKLWDGRT 111
++SGS D TL +W+ AE + + + GH + + + + + R+V S S D ++++WD T
Sbjct: 316 IISGSTDRTLKVWN-AETGECIHTLYGHTSTV-RCMHLHEKRVV-SGSRDATLRVWDIET 372
Query: 112 GKYLASLRGHVAAVYQIAWSADSRLLVSGSSDSTLKVWDVKAQKLAMDLPGHADEVYAVD 171
G+ L L GHVAAV + + D R +VSG+ D +KVWD + + L GH + VY++
Sbjct: 373 GQCLHVLMGHVAAVRCVQY--DGRRVVSGAYDFMVKVWDPETETCLHTLQGHTNRVYSLQ 430
Query: 172 WSPDGQRVASGGKDKCLRIW 191
+ DG V SG D +R+W
Sbjct: 431 F--DGIHVVSGSLDTSIRVW 448
Score = 74.3 bits (181), Expect = 6e-14
Identities = 48/142 (33%), Positives = 75/142 (52%), Gaps = 7/142 (4%)
Query: 50 ERLVSGSDDFTLFLWSPAEDKKPLTRMTGHQALINQVLFSPDSRIVASASFDKSIKLWDG 109
+R+VSGS D TL +W E + L + GH A + V + D R V S ++D +K+WD
Sbjct: 354 KRVVSGSRDATLRVWD-IETGQCLHVLMGHVAAVRCVQY--DGRRVVSGAYDFMVKVWDP 410
Query: 110 RTGKYLASLRGHVAAVYQIAWSADSRLLVSGSSDSTLKVWDVKAQKLAMDLPGHADEVYA 169
T L +L+GH VY + + D +VSGS D++++VWDV+ L GH
Sbjct: 411 ETETCLHTLQGHTNRVYSLQF--DGIHVVSGSLDTSIRVWDVETGNCIHTLTGHQSLTSG 468
Query: 170 VDWSPDGQRVASGGKDKCLRIW 191
++ + + SG D ++IW
Sbjct: 469 MELKDN--ILVSGNADSTVKIW 488
Score = 68.9 bits (167), Expect = 2e-12
Identities = 45/144 (31%), Positives = 74/144 (51%), Gaps = 10/144 (6%)
Query: 51 RLVSGSDDFTLFLWSPAEDKKPLTRMTGHQALINQVLFSPDSRIVASASFDKSIKLWDGR 110
R+VSG+ DF + +W P E + L + GH + + F D V S S D SI++WD
Sbjct: 395 RVVSGAYDFMVKVWDP-ETETCLHTLQGHTNRVYSLQF--DGIHVVSGSLDTSIRVWDVE 451
Query: 111 TGKYLASLRGHVAAVYQIAWSADSRLLVSGSSDSTLKVWDVKAQKLAMDLPG---HADEV 167
TG + +L GH + + +LVSG++DST+K+WD+K + L G H V
Sbjct: 452 TGNCIHTLTGHQSLTSGM--ELKDNILVSGNADSTVKIWDIKTGQCLQTLQGPNKHQSAV 509
Query: 168 YAVDWSPDGQRVASGGKDKCLRIW 191
+ ++ + V + D +++W
Sbjct: 510 TCLQFNKN--FVITSSDDGTVKLW 531
Score = 56.2 bits (134), Expect = 2e-08
Identities = 34/112 (30%), Positives = 66/112 (58%), Gaps = 8/112 (7%)
Query: 52 LVSGSDDFTLFLWSPAEDKKPLTRMTGHQALINQVLFSPDSRIVASASFDKSIKLWDGRT 111
+VSGS D ++ +W E + +TGHQ+L + + + I+ S + D ++K+WD +T
Sbjct: 436 VVSGSLDTSIRVWD-VETGNCIHTLTGHQSLTSGMELKDN--ILVSGNADSTVKIWDIKT 492
Query: 112 GKYLASLRG---HVAAVYQIAWSADSRLLVSGSSDSTLKVWDVKAQKLAMDL 160
G+ L +L+G H +AV + ++ + +++ S D T+K+WD+K + +L
Sbjct: 493 GQCLQTLQGPNKHQSAVTCLQFNKN--FVITSSDDGTVKLWDLKTGEFIRNL 542
Score = 40.4 bits (93), Expect = 0.001
Identities = 25/74 (33%), Positives = 36/74 (48%), Gaps = 3/74 (4%)
Query: 118 LRGHVAAVYQIAWSADSRLLVSGSSDSTLKVWDVKAQKLAMDLPGHADEVYAVDWSPDGQ 177
L+GH V +R+ VSGS D+TLKVW K L GH V++ +
Sbjct: 258 LKGHDDHVITCLQFCGNRI-VSGSDDNTLKVWSAVTGKCLRTLVGHTGGVWSSQMRDN-- 314
Query: 178 RVASGGKDKCLRIW 191
+ SG D+ L++W
Sbjct: 315 IIISGSTDRTLKVW 328
Score = 37.4 bits (85), Expect = 0.008
Identities = 28/101 (27%), Positives = 51/101 (50%), Gaps = 9/101 (8%)
Query: 52 LVSGSDDFTLFLWS--PAEDKKPLTRMTGHQALINQVLFSPDSRIVASASFDKSIKLWDG 109
LVSG+ D T+ +W + + L HQ+ + + F+ + V ++S D ++KLWD
Sbjct: 476 LVSGNADSTVKIWDIKTGQCLQTLQGPNKHQSAVTCLQFNKN--FVITSSDDGTVKLWDL 533
Query: 110 RTGKYLASL-----RGHVAAVYQIAWSADSRLLVSGSSDST 145
+TG+++ +L G V++I S + GS + T
Sbjct: 534 KTGEFIRNLVTLESGGSGGVVWRIRASNTKLVCAVGSRNGT 574
>gi|16117781 F-box and WD repeat domain containing 7 isoform 1 [Homo
sapiens]
Length = 707
Score = 83.6 bits (205), Expect = 1e-16
Identities = 53/143 (37%), Positives = 80/143 (55%), Gaps = 11/143 (7%)
Query: 51 RLVSGSDDFTLFLWSPAEDKKPLTRMTGHQALINQVLFSPDSR--IVASASFDKSIKLWD 108
R+VSGSDD TL +WS A K L + GH + +S R I+ S S D+++K+W+
Sbjct: 393 RIVSGSDDNTLKVWS-AVTGKCLRTLVGHTGGV----WSSQMRDNIIISGSTDRTLKVWN 447
Query: 109 GRTGKYLASLRGHVAAVYQIAWSADSRLLVSGSSDSTLKVWDVKAQKLAMDLPGHADEVY 168
TG+ + +L GH + V + +VSGS D+TL+VWD++ + L GH V
Sbjct: 448 AETGECIHTLYGHTSTVR--CMHLHEKRVVSGSRDATLRVWDIETGQCLHVLMGHVAAVR 505
Query: 169 AVDWSPDGQRVASGGKDKCLRIW 191
V + DG+RV SG D +++W
Sbjct: 506 CVQY--DGRRVVSGAYDFMVKVW 526
Score = 83.6 bits (205), Expect = 1e-16
Identities = 51/140 (36%), Positives = 82/140 (58%), Gaps = 7/140 (5%)
Query: 52 LVSGSDDFTLFLWSPAEDKKPLTRMTGHQALINQVLFSPDSRIVASASFDKSIKLWDGRT 111
++SGS D TL +W+ AE + + + GH + + + + + R+V S S D ++++WD T
Sbjct: 434 IISGSTDRTLKVWN-AETGECIHTLYGHTSTV-RCMHLHEKRVV-SGSRDATLRVWDIET 490
Query: 112 GKYLASLRGHVAAVYQIAWSADSRLLVSGSSDSTLKVWDVKAQKLAMDLPGHADEVYAVD 171
G+ L L GHVAAV + + D R +VSG+ D +KVWD + + L GH + VY++
Sbjct: 491 GQCLHVLMGHVAAVRCVQY--DGRRVVSGAYDFMVKVWDPETETCLHTLQGHTNRVYSLQ 548
Query: 172 WSPDGQRVASGGKDKCLRIW 191
+ DG V SG D +R+W
Sbjct: 549 F--DGIHVVSGSLDTSIRVW 566
Score = 74.3 bits (181), Expect = 6e-14
Identities = 48/142 (33%), Positives = 75/142 (52%), Gaps = 7/142 (4%)
Query: 50 ERLVSGSDDFTLFLWSPAEDKKPLTRMTGHQALINQVLFSPDSRIVASASFDKSIKLWDG 109
+R+VSGS D TL +W E + L + GH A + V + D R V S ++D +K+WD
Sbjct: 472 KRVVSGSRDATLRVWD-IETGQCLHVLMGHVAAVRCVQY--DGRRVVSGAYDFMVKVWDP 528
Query: 110 RTGKYLASLRGHVAAVYQIAWSADSRLLVSGSSDSTLKVWDVKAQKLAMDLPGHADEVYA 169
T L +L+GH VY + + D +VSGS D++++VWDV+ L GH
Sbjct: 529 ETETCLHTLQGHTNRVYSLQF--DGIHVVSGSLDTSIRVWDVETGNCIHTLTGHQSLTSG 586
Query: 170 VDWSPDGQRVASGGKDKCLRIW 191
++ + + SG D ++IW
Sbjct: 587 MELKDN--ILVSGNADSTVKIW 606
Score = 68.9 bits (167), Expect = 2e-12
Identities = 45/144 (31%), Positives = 74/144 (51%), Gaps = 10/144 (6%)
Query: 51 RLVSGSDDFTLFLWSPAEDKKPLTRMTGHQALINQVLFSPDSRIVASASFDKSIKLWDGR 110
R+VSG+ DF + +W P E + L + GH + + F D V S S D SI++WD
Sbjct: 513 RVVSGAYDFMVKVWDP-ETETCLHTLQGHTNRVYSLQF--DGIHVVSGSLDTSIRVWDVE 569
Query: 111 TGKYLASLRGHVAAVYQIAWSADSRLLVSGSSDSTLKVWDVKAQKLAMDLPG---HADEV 167
TG + +L GH + + +LVSG++DST+K+WD+K + L G H V
Sbjct: 570 TGNCIHTLTGHQSLTSGM--ELKDNILVSGNADSTVKIWDIKTGQCLQTLQGPNKHQSAV 627
Query: 168 YAVDWSPDGQRVASGGKDKCLRIW 191
+ ++ + V + D +++W
Sbjct: 628 TCLQFNKN--FVITSSDDGTVKLW 649
Score = 56.2 bits (134), Expect = 2e-08
Identities = 34/112 (30%), Positives = 66/112 (58%), Gaps = 8/112 (7%)
Query: 52 LVSGSDDFTLFLWSPAEDKKPLTRMTGHQALINQVLFSPDSRIVASASFDKSIKLWDGRT 111
+VSGS D ++ +W E + +TGHQ+L + + + I+ S + D ++K+WD +T
Sbjct: 554 VVSGSLDTSIRVWD-VETGNCIHTLTGHQSLTSGMELKDN--ILVSGNADSTVKIWDIKT 610
Query: 112 GKYLASLRG---HVAAVYQIAWSADSRLLVSGSSDSTLKVWDVKAQKLAMDL 160
G+ L +L+G H +AV + ++ + +++ S D T+K+WD+K + +L
Sbjct: 611 GQCLQTLQGPNKHQSAVTCLQFNKN--FVITSSDDGTVKLWDLKTGEFIRNL 660
Score = 40.4 bits (93), Expect = 0.001
Identities = 25/74 (33%), Positives = 36/74 (48%), Gaps = 3/74 (4%)
Query: 118 LRGHVAAVYQIAWSADSRLLVSGSSDSTLKVWDVKAQKLAMDLPGHADEVYAVDWSPDGQ 177
L+GH V +R+ VSGS D+TLKVW K L GH V++ +
Sbjct: 376 LKGHDDHVITCLQFCGNRI-VSGSDDNTLKVWSAVTGKCLRTLVGHTGGVWSSQMRDN-- 432
Query: 178 RVASGGKDKCLRIW 191
+ SG D+ L++W
Sbjct: 433 IIISGSTDRTLKVW 446
Score = 37.4 bits (85), Expect = 0.008
Identities = 28/101 (27%), Positives = 51/101 (50%), Gaps = 9/101 (8%)
Query: 52 LVSGSDDFTLFLWS--PAEDKKPLTRMTGHQALINQVLFSPDSRIVASASFDKSIKLWDG 109
LVSG+ D T+ +W + + L HQ+ + + F+ + V ++S D ++KLWD
Sbjct: 594 LVSGNADSTVKIWDIKTGQCLQTLQGPNKHQSAVTCLQFNKN--FVITSSDDGTVKLWDL 651
Query: 110 RTGKYLASL-----RGHVAAVYQIAWSADSRLLVSGSSDST 145
+TG+++ +L G V++I S + GS + T
Sbjct: 652 KTGEFIRNLVTLESGGSGGVVWRIRASNTKLVCAVGSRNGT 692
>gi|16117779 F-box and WD repeat domain containing 7 isoform 2 [Homo
sapiens]
Length = 627
Score = 83.6 bits (205), Expect = 1e-16
Identities = 53/143 (37%), Positives = 80/143 (55%), Gaps = 11/143 (7%)
Query: 51 RLVSGSDDFTLFLWSPAEDKKPLTRMTGHQALINQVLFSPDSR--IVASASFDKSIKLWD 108
R+VSGSDD TL +WS A K L + GH + +S R I+ S S D+++K+W+
Sbjct: 313 RIVSGSDDNTLKVWS-AVTGKCLRTLVGHTGGV----WSSQMRDNIIISGSTDRTLKVWN 367
Query: 109 GRTGKYLASLRGHVAAVYQIAWSADSRLLVSGSSDSTLKVWDVKAQKLAMDLPGHADEVY 168
TG+ + +L GH + V + +VSGS D+TL+VWD++ + L GH V
Sbjct: 368 AETGECIHTLYGHTSTVR--CMHLHEKRVVSGSRDATLRVWDIETGQCLHVLMGHVAAVR 425
Query: 169 AVDWSPDGQRVASGGKDKCLRIW 191
V + DG+RV SG D +++W
Sbjct: 426 CVQY--DGRRVVSGAYDFMVKVW 446
Score = 83.6 bits (205), Expect = 1e-16
Identities = 51/140 (36%), Positives = 82/140 (58%), Gaps = 7/140 (5%)
Query: 52 LVSGSDDFTLFLWSPAEDKKPLTRMTGHQALINQVLFSPDSRIVASASFDKSIKLWDGRT 111
++SGS D TL +W+ AE + + + GH + + + + + R+V S S D ++++WD T
Sbjct: 354 IISGSTDRTLKVWN-AETGECIHTLYGHTSTV-RCMHLHEKRVV-SGSRDATLRVWDIET 410
Query: 112 GKYLASLRGHVAAVYQIAWSADSRLLVSGSSDSTLKVWDVKAQKLAMDLPGHADEVYAVD 171
G+ L L GHVAAV + + D R +VSG+ D +KVWD + + L GH + VY++
Sbjct: 411 GQCLHVLMGHVAAVRCVQY--DGRRVVSGAYDFMVKVWDPETETCLHTLQGHTNRVYSLQ 468
Query: 172 WSPDGQRVASGGKDKCLRIW 191
+ DG V SG D +R+W
Sbjct: 469 F--DGIHVVSGSLDTSIRVW 486
Score = 74.3 bits (181), Expect = 6e-14
Identities = 48/142 (33%), Positives = 75/142 (52%), Gaps = 7/142 (4%)
Query: 50 ERLVSGSDDFTLFLWSPAEDKKPLTRMTGHQALINQVLFSPDSRIVASASFDKSIKLWDG 109
+R+VSGS D TL +W E + L + GH A + V + D R V S ++D +K+WD
Sbjct: 392 KRVVSGSRDATLRVWD-IETGQCLHVLMGHVAAVRCVQY--DGRRVVSGAYDFMVKVWDP 448
Query: 110 RTGKYLASLRGHVAAVYQIAWSADSRLLVSGSSDSTLKVWDVKAQKLAMDLPGHADEVYA 169
T L +L+GH VY + + D +VSGS D++++VWDV+ L GH
Sbjct: 449 ETETCLHTLQGHTNRVYSLQF--DGIHVVSGSLDTSIRVWDVETGNCIHTLTGHQSLTSG 506
Query: 170 VDWSPDGQRVASGGKDKCLRIW 191
++ + + SG D ++IW
Sbjct: 507 MELKDN--ILVSGNADSTVKIW 526
Score = 68.9 bits (167), Expect = 2e-12
Identities = 45/144 (31%), Positives = 74/144 (51%), Gaps = 10/144 (6%)
Query: 51 RLVSGSDDFTLFLWSPAEDKKPLTRMTGHQALINQVLFSPDSRIVASASFDKSIKLWDGR 110
R+VSG+ DF + +W P E + L + GH + + F D V S S D SI++WD
Sbjct: 433 RVVSGAYDFMVKVWDP-ETETCLHTLQGHTNRVYSLQF--DGIHVVSGSLDTSIRVWDVE 489
Query: 111 TGKYLASLRGHVAAVYQIAWSADSRLLVSGSSDSTLKVWDVKAQKLAMDLPG---HADEV 167
TG + +L GH + + +LVSG++DST+K+WD+K + L G H V
Sbjct: 490 TGNCIHTLTGHQSLTSGM--ELKDNILVSGNADSTVKIWDIKTGQCLQTLQGPNKHQSAV 547
Query: 168 YAVDWSPDGQRVASGGKDKCLRIW 191
+ ++ + V + D +++W
Sbjct: 548 TCLQFNKN--FVITSSDDGTVKLW 569
Score = 56.2 bits (134), Expect = 2e-08
Identities = 34/112 (30%), Positives = 66/112 (58%), Gaps = 8/112 (7%)
Query: 52 LVSGSDDFTLFLWSPAEDKKPLTRMTGHQALINQVLFSPDSRIVASASFDKSIKLWDGRT 111
+VSGS D ++ +W E + +TGHQ+L + + + I+ S + D ++K+WD +T
Sbjct: 474 VVSGSLDTSIRVWD-VETGNCIHTLTGHQSLTSGMELKDN--ILVSGNADSTVKIWDIKT 530
Query: 112 GKYLASLRG---HVAAVYQIAWSADSRLLVSGSSDSTLKVWDVKAQKLAMDL 160
G+ L +L+G H +AV + ++ + +++ S D T+K+WD+K + +L
Sbjct: 531 GQCLQTLQGPNKHQSAVTCLQFNKN--FVITSSDDGTVKLWDLKTGEFIRNL 580
Score = 40.4 bits (93), Expect = 0.001
Identities = 25/74 (33%), Positives = 36/74 (48%), Gaps = 3/74 (4%)
Query: 118 LRGHVAAVYQIAWSADSRLLVSGSSDSTLKVWDVKAQKLAMDLPGHADEVYAVDWSPDGQ 177
L+GH V +R+ VSGS D+TLKVW K L GH V++ +
Sbjct: 296 LKGHDDHVITCLQFCGNRI-VSGSDDNTLKVWSAVTGKCLRTLVGHTGGVWSSQMRDN-- 352
Query: 178 RVASGGKDKCLRIW 191
+ SG D+ L++W
Sbjct: 353 IIISGSTDRTLKVW 366
Score = 37.4 bits (85), Expect = 0.008
Identities = 28/101 (27%), Positives = 51/101 (50%), Gaps = 9/101 (8%)
Query: 52 LVSGSDDFTLFLWS--PAEDKKPLTRMTGHQALINQVLFSPDSRIVASASFDKSIKLWDG 109
LVSG+ D T+ +W + + L HQ+ + + F+ + V ++S D ++KLWD
Sbjct: 514 LVSGNADSTVKIWDIKTGQCLQTLQGPNKHQSAVTCLQFNKN--FVITSSDDGTVKLWDL 571
Query: 110 RTGKYLASL-----RGHVAAVYQIAWSADSRLLVSGSSDST 145
+TG+++ +L G V++I S + GS + T
Sbjct: 572 KTGEFIRNLVTLESGGSGGVVWRIRASNTKLVCAVGSRNGT 612
>gi|115298668 WD repeat domain 57 (U5 snRNP specific) [Homo sapiens]
Length = 357
Score = 82.4 bits (202), Expect = 2e-16
Identities = 46/153 (30%), Positives = 79/153 (51%), Gaps = 10/153 (6%)
Query: 47 QGPERLVSGSDDFTLFLWSPAEDKKPLTRMTGHQALINQVLFSPDSRIVASASFDKSIKL 106
+GP+ + +GSDD T+ LW + T +Q L V F+ S + S D IK+
Sbjct: 162 RGPQLVCTGSDDGTVKLWDIRKKAAIQTFQNTYQVLA--VTFNDTSDQIISGGIDNDIKV 219
Query: 107 WDGRTGKYLASLRGHVAAVYQIAWSADSRLLVSGSSDSTLKVWDVK----AQKLAMDLPG 162
WD R K ++RGH +V ++ S++ L+S + D+T++VWDV+ ++ G
Sbjct: 220 WDLRQNKLTYTMRGHADSVTGLSLSSEGSYLLSNAMDNTVRVWDVRPFAPKERCVKIFQG 279
Query: 163 HA----DEVYAVDWSPDGQRVASGGKDKCLRIW 191
+ + WSPDG ++A+G D+ + +W
Sbjct: 280 NVHNFEKNLLRCSWSPDGSKIAAGSADRFVYVW 312
Score = 75.9 bits (185), Expect = 2e-14
Identities = 40/141 (28%), Positives = 75/141 (53%), Gaps = 2/141 (1%)
Query: 52 LVSGSDDFTLFLWSPAEDKKPLTRMTGHQALINQVLFSPDSRIVASASFDKSIKLWDGRT 111
L S D + LW+ D + GH + ++ ++ D ++ SAS DK++ +WD T
Sbjct: 81 LASAGFDRLILLWNVYGDCDNYATLKGHSGAVMELHYNTDGSMLFSASTDKTVAVWDSET 140
Query: 112 GKYLASLRGHVAAVYQ-IAWSADSRLLVSGSSDSTLKVWDVKAQKLAMDLPGHADEVYAV 170
G+ + L+GH + V +L+ +GS D T+K+WD++ +K A+ + +V AV
Sbjct: 141 GERVKRLKGHTSFVNSCYPARRGPQLVCTGSDDGTVKLWDIR-KKAAIQTFQNTYQVLAV 199
Query: 171 DWSPDGQRVASGGKDKCLRIW 191
++ ++ SGG D +++W
Sbjct: 200 TFNDTSDQIISGGIDNDIKVW 220
Score = 68.6 bits (166), Expect = 3e-12
Identities = 40/123 (32%), Positives = 66/123 (53%), Gaps = 4/123 (3%)
Query: 72 PLTRMTGHQALINQVLFSPDSRIVASASFDKSIKLWD--GRTGKYLASLRGHVAAVYQIA 129
P+ ++GH+ + F P+ +ASA FD+ I LW+ G Y A+L+GH AV ++
Sbjct: 58 PIMLLSGHEGEVYCCKFHPNGSTLASAGFDRLILLWNVYGDCDNY-ATLKGHSGAVMELH 116
Query: 130 WSADSRLLVSGSSDSTLKVWDVKAQKLAMDLPGHADEVYAVDWSPDG-QRVASGGKDKCL 188
++ D +L S S+D T+ VWD + + L GH V + + G Q V +G D +
Sbjct: 117 YNTDGSMLFSASTDKTVAVWDSETGERVKRLKGHTSFVNSCYPARRGPQLVCTGSDDGTV 176
Query: 189 RIW 191
++W
Sbjct: 177 KLW 179
Score = 46.6 bits (109), Expect = 1e-05
Identities = 19/65 (29%), Positives = 39/65 (60%)
Query: 88 FSPDSRIVASASFDKSIKLWDGRTGKYLASLRGHVAAVYQIAWSADSRLLVSGSSDSTLK 147
+SPD +A+ S D+ + +WD + + L L GH ++ ++A+ D +++S SSD L
Sbjct: 293 WSPDGSKIAAGSADRFVYVWDTTSRRILYKLPGHAGSINEVAFHPDEPIIISASSDKRLY 352
Query: 148 VWDVK 152
+ +++
Sbjct: 353 MGEIQ 357
>gi|4505895 pleiotropic regulator 1 (PRL1 homolog, Arabidopsis)
[Homo sapiens]
Length = 514
Score = 82.4 bits (202), Expect = 2e-16
Identities = 46/144 (31%), Positives = 73/144 (50%), Gaps = 1/144 (0%)
Query: 48 GPERLVSGSDDFTLFLWSPAEDKKPLTRMTGHQALINQVLFSPDSRIVASASFDKSIKLW 107
G + V+GS D T+ +W A K L+ +TGH + + V+ S S + S DK +K W
Sbjct: 215 GNQWFVTGSADRTIKIWDLASGKLKLS-LTGHISTVRGVIVSTRSPYLFSCGEDKQVKCW 273
Query: 108 DGRTGKYLASLRGHVAAVYQIAWSADSRLLVSGSSDSTLKVWDVKAQKLAMDLPGHADEV 167
D K + GH++AVY + +LV+ S DST ++WDV+ + L GH + V
Sbjct: 274 DLEYNKVIRHYHGHLSAVYGLDLHPTIDVLVTCSRDSTARIWDVRTKASVHTLSGHTNAV 333
Query: 168 YAVDWSPDGQRVASGGKDKCLRIW 191
V ++ +G D +R+W
Sbjct: 334 ATVRCQAAEPQIITGSHDTTIRLW 357
Score = 69.7 bits (169), Expect = 1e-12
Identities = 35/116 (30%), Positives = 57/116 (49%)
Query: 76 MTGHQALINQVLFSPDSRIVASASFDKSIKLWDGRTGKYLASLRGHVAAVYQIAWSADSR 135
++GH + + P ++ + S D++IK+WD +GK SL GH++ V + S S
Sbjct: 200 ISGHLGWVRCIAVEPGNQWFVTGSADRTIKIWDLASGKLKLSLTGHISTVRGVIVSTRSP 259
Query: 136 LLVSGSSDSTLKVWDVKAQKLAMDLPGHADEVYAVDWSPDGQRVASGGKDKCLRIW 191
L S D +K WD++ K+ GH VY +D P + + +D RIW
Sbjct: 260 YLFSCGEDKQVKCWDLEYNKVIRHYHGHLSAVYGLDLHPTIDVLVTCSRDSTARIW 315
Score = 64.3 bits (155), Expect = 6e-11
Identities = 40/141 (28%), Positives = 67/141 (47%), Gaps = 2/141 (1%)
Query: 52 LVSGSDDFTLFLWSPAEDKKPLTRMTGHQALINQVLFSPDSRIVASASFDKSIKLWDGRT 111
L S +D + W E K + GH + + + P ++ + S D + ++WD RT
Sbjct: 261 LFSCGEDKQVKCWD-LEYNKVIRHYHGHLSAVYGLDLHPTIDVLVTCSRDSTARIWDVRT 319
Query: 112 GKYLASLRGHVAAVYQIAWSADSRLLVSGSSDSTLKVWDVKAQKLAMDLPGHADEVYAVD 171
+ +L GH AV + A +++GS D+T+++WD+ A K + L H V AV
Sbjct: 320 KASVHTLSGHTNAVATVRCQAAEPQIITGSHDTTIRLWDLVAGKTRVTLTNHKKSVRAVV 379
Query: 172 WSPDGQRVASGGKDKCLRIWR 192
P ASG D ++ W+
Sbjct: 380 LHPRHYTFASGSPDN-IKQWK 399
Score = 61.2 bits (147), Expect = 5e-10
Identities = 46/158 (29%), Positives = 81/158 (51%), Gaps = 12/158 (7%)
Query: 44 VRGQGPE-RLVSGSDDFTLFLWSPAEDKKPLTRMTGHQALINQVLFSPDSRIVASASFDK 102
VR Q E ++++GS D T+ LW K +T +T H+ + V+ P AS S D
Sbjct: 336 VRCQAAEPQIITGSHDTTIRLWDLVAGKTRVT-LTNHKKSVRAVVLHPRHYTFASGSPD- 393
Query: 103 SIKLWDGRTGKYLASLRGHVAAVYQIAWSADSRLLVSGSSDSTLKVWDVKA----QKL-A 157
+IK W G ++ +L GH A + + ++D +LVSG+ + T+ +WD + Q++ A
Sbjct: 394 NIKQWKFPDGSFIQNLSGHNAIINTLTVNSDG-VLVSGADNGTMHLWDWRTGYNFQRVHA 452
Query: 158 MDLPGHADE---VYAVDWSPDGQRVASGGKDKCLRIWR 192
PG D ++A + R+ + DK ++++R
Sbjct: 453 AVQPGSLDSESGIFACAFDQSESRLLTAEADKTIKVYR 490
>gi|19913367 transducin beta-like 1Y [Homo sapiens]
Length = 522
Score = 82.4 bits (202), Expect = 2e-16
Identities = 43/129 (33%), Positives = 67/129 (51%), Gaps = 9/129 (6%)
Query: 72 PLTRMTGHQALINQVLFSPDSRIVASASFDKSIKLWDGRTGKYLASLRGHVAAVYQIAWS 131
P+ GH +N + + P ++AS S D ++K+W + + L+ H +Y I WS
Sbjct: 351 PVKTFQGHTNEVNAIKWDPSGMLLASCSDDMTLKIWSMKQDACVHDLQAHSKEIYTIKWS 410
Query: 132 A---------DSRLLVSGSSDSTLKVWDVKAQKLAMDLPGHADEVYAVDWSPDGQRVASG 182
S +L S S DST+++WDV+ L H + VY+V +SPDG+ +ASG
Sbjct: 411 PTGPATSNPNSSIMLASASFDSTVRLWDVEQGVCTHTLMKHQEPVYSVAFSPDGKYLASG 470
Query: 183 GKDKCLRIW 191
DK + IW
Sbjct: 471 SFDKYVHIW 479
Score = 72.8 bits (177), Expect = 2e-13
Identities = 45/143 (31%), Positives = 70/143 (48%), Gaps = 11/143 (7%)
Query: 52 LVSGSDDFTLFLWSPAEDKKPLTRMTGHQALINQVLFSP---------DSRIVASASFDK 102
L S SDD TL +WS +D + + H I + +SP S ++ASASFD
Sbjct: 374 LASCSDDMTLKIWSMKQDAC-VHDLQAHSKEIYTIKWSPTGPATSNPNSSIMLASASFDS 432
Query: 103 SIKLWDGRTGKYLASLRGHVAAVYQIAWSADSRLLVSGSSDSTLKVWDVKAQKLAMDLPG 162
+++LWD G +L H VY +A+S D + L SGS D + +W+ ++ L G
Sbjct: 433 TVRLWDVEQGVCTHTLMKHQEPVYSVAFSPDGKYLASGSFDKYVHIWNTQSGSLVHSYQG 492
Query: 163 HADEVYAVDWSPDGQRVASGGKD 185
++ V W+ G +V + D
Sbjct: 493 -TGGIFEVCWNARGDKVGASASD 514
Score = 61.2 bits (147), Expect = 5e-10
Identities = 46/190 (24%), Positives = 69/190 (36%), Gaps = 52/190 (27%)
Query: 52 LVSGSDDFTLFLWSPAEDKKPLTRMTGHQALINQVLFSPDSRIVASASFDKSIKLWDGRT 111
L GS D +W+ E+ + + H+ I + ++ V SA DK+ +WD T
Sbjct: 250 LAMGSYDGFARIWT--ENGNLASTLGQHKGPIFALKWNKKGNYVLSAGVDKTTIIWDAHT 307
Query: 112 GKY-----------------------------------------LASLRGHVAAVYQIAW 130
G+ + + +GH V I W
Sbjct: 308 GEAKQQFPFHSAPALDVDWQNNMTFASCSTDMCIHVCRLGCDHPVKTFQGHTNEVNAIKW 367
Query: 131 SADSRLLVSGSSDSTLKVWDVKAQKLAMDLPGHADEVYAVDWSPDGQ---------RVAS 181
LL S S D TLK+W +K DL H+ E+Y + WSP G +AS
Sbjct: 368 DPSGMLLASCSDDMTLKIWSMKQDACVHDLQAHSKEIYTIKWSPTGPATSNPNSSIMLAS 427
Query: 182 GGKDKCLRIW 191
D +R+W
Sbjct: 428 ASFDSTVRLW 437
Score = 55.1 bits (131), Expect = 4e-08
Identities = 37/154 (24%), Positives = 62/154 (40%), Gaps = 15/154 (9%)
Query: 52 LVSGSDDFTLFLWSPAEDK---------KPLTRMTGHQALINQVLFS----PDSRIVASA 98
L SGS D T +W+ E+ + R GH N+ + S D ++A
Sbjct: 194 LASGSGDSTARIWNLNENSNGGSTQLVLRHCIREGGHDVPSNKDVTSLDWNSDGTLLAMG 253
Query: 99 SFDKSIKLWDGRTGKYLASLRGHVAAVYQIAWSADSRLLVSGSSDSTLKVWDVKAQKLAM 158
S+D ++W G ++L H ++ + W+ ++S D T +WD +
Sbjct: 254 SYDGFARIWT-ENGNLASTLGQHKGPIFALKWNKKGNYVLSAGVDKTTIIWDAHTGEAKQ 312
Query: 159 DLPGHADEVYAVDWSPDGQRVASGGKDKCLRIWR 192
P H+ VDW + AS D C+ + R
Sbjct: 313 QFPFHSAPALDVDWQ-NNMTFASCSTDMCIHVCR 345
Score = 54.3 bits (129), Expect = 6e-08
Identities = 38/132 (28%), Positives = 60/132 (45%), Gaps = 15/132 (11%)
Query: 74 TRMTGHQALINQVLFSPDSRIVASASFDKSIKLW----DGRTGKYLASLR------GHVA 123
T + GH++ + ++P S ++AS S D + ++W + G LR GH
Sbjct: 173 TVLRGHESEVFICAWNPVSDLLASGSGDSTARIWNLNENSNGGSTQLVLRHCIREGGHDV 232
Query: 124 A----VYQIAWSADSRLLVSGSSDSTLKVWDVKAQKLAMDLPGHADEVYAVDWSPDGQRV 179
V + W++D LL GS D ++W + LA L H ++A+ W+ G V
Sbjct: 233 PSNKDVTSLDWNSDGTLLAMGSYDGFARIW-TENGNLASTLGQHKGPIFALKWNKKGNYV 291
Query: 180 ASGGKDKCLRIW 191
S G DK IW
Sbjct: 292 LSAGVDKTTIIW 303
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.316 0.131 0.394
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 7,384,196
Number of Sequences: 37866
Number of extensions: 291891
Number of successful extensions: 3152
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 311
Number of HSP's successfully gapped in prelim test: 41
Number of HSP's that attempted gapping in prelim test: 719
Number of HSP's gapped (non-prelim): 1472
length of query: 193
length of database: 18,247,518
effective HSP length: 97
effective length of query: 96
effective length of database: 14,574,516
effective search space: 1399153536
effective search space used: 1399153536
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 59 (27.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.