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Search of human proteins with 62198237
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|62198237 DNA-directed DNA polymerase epsilon [Homo sapiens]
(2286 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|62198237 DNA-directed DNA polymerase epsilon [Homo sapiens] 4619 0.0
gi|106507301 DNA-directed DNA polymerase alpha 1 [Homo sapiens] 49 6e-05
gi|115511012 coiled-coil domain containing 136 [Homo sapiens] 42 0.007
gi|86262149 zinc finger and BTB domain containing 7C [Homo sapiens] 42 0.007
gi|151101407 prothymosin, alpha isoform 1 [Homo sapiens] 41 0.012
gi|151101404 prothymosin, alpha isoform 2 [Homo sapiens] 41 0.012
gi|58761548 tau tubulin kinase 1 [Homo sapiens] 40 0.020
gi|100816397 MYST histone acetyltransferase (monocytic leukemia)... 40 0.020
gi|209862789 microtubule associated monoxygenase, calponin and L... 40 0.020
gi|4759128 solute carrier family 24 (sodium/potassium/calcium ex... 40 0.034
gi|118600967 shroom family member 4 [Homo sapiens] 39 0.045
gi|113204617 skeletal muscle ryanodine receptor isoform 2 [Homo ... 39 0.045
gi|113204615 skeletal muscle ryanodine receptor isoform 1 [Homo ... 39 0.045
gi|227496440 multiple C2 domains, transmembrane 2 isoform 1 [Hom... 39 0.059
gi|118498345 AT-binding transcription factor 1 [Homo sapiens] 39 0.059
gi|17975763 myelin transcription factor 1 [Homo sapiens] 39 0.077
gi|154759293 cysteine-rich hydrophobic domain 1 [Homo sapiens] 39 0.077
gi|22035679 AT rich interactive domain 4B isoform 2 [Homo sapiens] 39 0.077
gi|22035677 AT rich interactive domain 4B isoform 1 [Homo sapiens] 39 0.077
gi|211904182 DDB1 and CUL4 associated factor 8-like 2 [Homo sapi... 38 0.100
gi|56711320 hypothetical protein LOC145407 [Homo sapiens] 38 0.100
gi|124244056 family with sequence similarity 123B [Homo sapiens] 38 0.13
gi|4503257 death-domain associated protein isoform a [Homo sapiens] 38 0.13
gi|215422388 death-domain associated protein isoform a [Homo sap... 38 0.13
gi|215422366 death-domain associated protein isoform b [Homo sap... 38 0.13
gi|195546902 suppressor of Ty 5 homolog isoform b [Homo sapiens] 38 0.13
gi|195546900 suppressor of Ty 5 homolog isoform a [Homo sapiens] 38 0.13
gi|161169023 suppressor of Ty 5 homolog isoform a [Homo sapiens] 38 0.13
gi|20149524 suppressor of Ty 5 homolog isoform a [Homo sapiens] 38 0.13
gi|4506411 Ran GTPase activating protein 1 [Homo sapiens] 38 0.13
>gi|62198237 DNA-directed DNA polymerase epsilon [Homo sapiens]
Length = 2286
Score = 4619 bits (11981), Expect = 0.0
Identities = 2286/2286 (100%), Positives = 2286/2286 (100%)
Query: 1 MSLRSGGRRRADPGADGEASRDDGATSSVSALKRLERSQWTDKMDLRFGFERLKEPGEKT 60
MSLRSGGRRRADPGADGEASRDDGATSSVSALKRLERSQWTDKMDLRFGFERLKEPGEKT
Sbjct: 1 MSLRSGGRRRADPGADGEASRDDGATSSVSALKRLERSQWTDKMDLRFGFERLKEPGEKT 60
Query: 61 GWLINMHPTEILDEDKRLGSAVDYYFIQDDGSRFKVALPYKPYFYIATRKGCEREVSSFL 120
GWLINMHPTEILDEDKRLGSAVDYYFIQDDGSRFKVALPYKPYFYIATRKGCEREVSSFL
Sbjct: 61 GWLINMHPTEILDEDKRLGSAVDYYFIQDDGSRFKVALPYKPYFYIATRKGCEREVSSFL 120
Query: 121 SKKFQGKIAKVETVPKEDLDLPNHLVGLKRNYIRLSFHTVEDLVKVRKEISPAVKKNREQ 180
SKKFQGKIAKVETVPKEDLDLPNHLVGLKRNYIRLSFHTVEDLVKVRKEISPAVKKNREQ
Sbjct: 121 SKKFQGKIAKVETVPKEDLDLPNHLVGLKRNYIRLSFHTVEDLVKVRKEISPAVKKNREQ 180
Query: 181 DHASDAYTALLSSVLQRGGVITDEEETSKKIADQLDNIVDMREYDVPYHIRLSIDLKIHV 240
DHASDAYTALLSSVLQRGGVITDEEETSKKIADQLDNIVDMREYDVPYHIRLSIDLKIHV
Sbjct: 181 DHASDAYTALLSSVLQRGGVITDEEETSKKIADQLDNIVDMREYDVPYHIRLSIDLKIHV 240
Query: 241 AHWYNVRYRGNAFPVEITRRDDLVERPDPVVLAFDIETTKLPLKFPDAETDQIMMISYMI 300
AHWYNVRYRGNAFPVEITRRDDLVERPDPVVLAFDIETTKLPLKFPDAETDQIMMISYMI
Sbjct: 241 AHWYNVRYRGNAFPVEITRRDDLVERPDPVVLAFDIETTKLPLKFPDAETDQIMMISYMI 300
Query: 301 DGQGYLITNREIVSEDIEDFEFTPKPEYEGPFCVFNEPDEAHLIQRWFEHVQETKPTIMV 360
DGQGYLITNREIVSEDIEDFEFTPKPEYEGPFCVFNEPDEAHLIQRWFEHVQETKPTIMV
Sbjct: 301 DGQGYLITNREIVSEDIEDFEFTPKPEYEGPFCVFNEPDEAHLIQRWFEHVQETKPTIMV 360
Query: 361 TYNGDFFDWPFVEARAAVHGLSMQQEIGFQKDSQGEYKAPQCIHMDCLRWVKRDSYLPVG 420
TYNGDFFDWPFVEARAAVHGLSMQQEIGFQKDSQGEYKAPQCIHMDCLRWVKRDSYLPVG
Sbjct: 361 TYNGDFFDWPFVEARAAVHGLSMQQEIGFQKDSQGEYKAPQCIHMDCLRWVKRDSYLPVG 420
Query: 421 SHNLKAAAKAKLGYDPVELDPEDMCRMATEQPQTLATYSVSDAVATYYLYMKYVHPFIFA 480
SHNLKAAAKAKLGYDPVELDPEDMCRMATEQPQTLATYSVSDAVATYYLYMKYVHPFIFA
Sbjct: 421 SHNLKAAAKAKLGYDPVELDPEDMCRMATEQPQTLATYSVSDAVATYYLYMKYVHPFIFA 480
Query: 481 LCTIIPMEPDEVLRKGSGTLCEALLMVQAFHANIIFPNKQEQEFNKLTDDGHVLDSETYV 540
LCTIIPMEPDEVLRKGSGTLCEALLMVQAFHANIIFPNKQEQEFNKLTDDGHVLDSETYV
Sbjct: 481 LCTIIPMEPDEVLRKGSGTLCEALLMVQAFHANIIFPNKQEQEFNKLTDDGHVLDSETYV 540
Query: 541 GGHVEALESGVFRSDIPCRFRMNPAAFDFLLQRVEKTLRHALEEEEKVPVEQVTNFEEVC 600
GGHVEALESGVFRSDIPCRFRMNPAAFDFLLQRVEKTLRHALEEEEKVPVEQVTNFEEVC
Sbjct: 541 GGHVEALESGVFRSDIPCRFRMNPAAFDFLLQRVEKTLRHALEEEEKVPVEQVTNFEEVC 600
Query: 601 DEIKSKLASLKDVPSRIECPLIYHLDVGAMYPNIILTNRLQPSAMVDEATCAACDFNKPG 660
DEIKSKLASLKDVPSRIECPLIYHLDVGAMYPNIILTNRLQPSAMVDEATCAACDFNKPG
Sbjct: 601 DEIKSKLASLKDVPSRIECPLIYHLDVGAMYPNIILTNRLQPSAMVDEATCAACDFNKPG 660
Query: 661 ANCQRKMAWQWRGEFMPASRSEYHRIQHQLESEKFPPLFPEGPARAFHELSREEQAKYEK 720
ANCQRKMAWQWRGEFMPASRSEYHRIQHQLESEKFPPLFPEGPARAFHELSREEQAKYEK
Sbjct: 661 ANCQRKMAWQWRGEFMPASRSEYHRIQHQLESEKFPPLFPEGPARAFHELSREEQAKYEK 720
Query: 721 RRLADYCRKAYKKIHITKVEERLTTICQRENSFYVDTVRAFRDRRYEFKGLHKVWKKKLS 780
RRLADYCRKAYKKIHITKVEERLTTICQRENSFYVDTVRAFRDRRYEFKGLHKVWKKKLS
Sbjct: 721 RRLADYCRKAYKKIHITKVEERLTTICQRENSFYVDTVRAFRDRRYEFKGLHKVWKKKLS 780
Query: 781 AAVEVGDAAEVKRCKNMEVLYDSLQLAHKCILNSFYGYVMRKGARWYSMEMAGIVCFTGA 840
AAVEVGDAAEVKRCKNMEVLYDSLQLAHKCILNSFYGYVMRKGARWYSMEMAGIVCFTGA
Sbjct: 781 AAVEVGDAAEVKRCKNMEVLYDSLQLAHKCILNSFYGYVMRKGARWYSMEMAGIVCFTGA 840
Query: 841 NIITQARELIEQIGRPLELDTDGIWCVLPNSFPENFVFKTTNVKKPKVTISYPGAMLNIM 900
NIITQARELIEQIGRPLELDTDGIWCVLPNSFPENFVFKTTNVKKPKVTISYPGAMLNIM
Sbjct: 841 NIITQARELIEQIGRPLELDTDGIWCVLPNSFPENFVFKTTNVKKPKVTISYPGAMLNIM 900
Query: 901 VKEGFTNDQYQELAEPSSLTYVTRSENSIFFEVDGPYLAMILPASKEEGKKLKKRYAVFN 960
VKEGFTNDQYQELAEPSSLTYVTRSENSIFFEVDGPYLAMILPASKEEGKKLKKRYAVFN
Sbjct: 901 VKEGFTNDQYQELAEPSSLTYVTRSENSIFFEVDGPYLAMILPASKEEGKKLKKRYAVFN 960
Query: 961 EDGSLAELKGFEVKRRGELQLIKIFQSSVFEAFLKGSTLEEVYGSVAKVADYWLDVLYSK 1020
EDGSLAELKGFEVKRRGELQLIKIFQSSVFEAFLKGSTLEEVYGSVAKVADYWLDVLYSK
Sbjct: 961 EDGSLAELKGFEVKRRGELQLIKIFQSSVFEAFLKGSTLEEVYGSVAKVADYWLDVLYSK 1020
Query: 1021 AANMPDSELFELISENRSMSRKLEDYGEQKSTSISTAKRLAEFLGDQMVKDAGLSCRYII 1080
AANMPDSELFELISENRSMSRKLEDYGEQKSTSISTAKRLAEFLGDQMVKDAGLSCRYII
Sbjct: 1021 AANMPDSELFELISENRSMSRKLEDYGEQKSTSISTAKRLAEFLGDQMVKDAGLSCRYII 1080
Query: 1081 SRKPEGSPVTERAIPLAIFQAEPTVRKHFLRKWLKSSSLQDFDIRAILDWDYYIERLGSA 1140
SRKPEGSPVTERAIPLAIFQAEPTVRKHFLRKWLKSSSLQDFDIRAILDWDYYIERLGSA
Sbjct: 1081 SRKPEGSPVTERAIPLAIFQAEPTVRKHFLRKWLKSSSLQDFDIRAILDWDYYIERLGSA 1140
Query: 1141 IQKIITIPAALQQVKNPVPRVKHPDWLHKKLLEKNDVYKQKKISELFTLEGRRQVTMAEA 1200
IQKIITIPAALQQVKNPVPRVKHPDWLHKKLLEKNDVYKQKKISELFTLEGRRQVTMAEA
Sbjct: 1141 IQKIITIPAALQQVKNPVPRVKHPDWLHKKLLEKNDVYKQKKISELFTLEGRRQVTMAEA 1200
Query: 1201 SEDSPRPSAPDMEDFGLVKLPHPAAPVTVKRKRVLWESQEESQDLTPTVPWQEILGQPPA 1260
SEDSPRPSAPDMEDFGLVKLPHPAAPVTVKRKRVLWESQEESQDLTPTVPWQEILGQPPA
Sbjct: 1201 SEDSPRPSAPDMEDFGLVKLPHPAAPVTVKRKRVLWESQEESQDLTPTVPWQEILGQPPA 1260
Query: 1261 LGTSQEEWLVWLRFHKKKWQLQARQRLARRKRQRLESAEGVLRPGAIRDGPATGLGSFLR 1320
LGTSQEEWLVWLRFHKKKWQLQARQRLARRKRQRLESAEGVLRPGAIRDGPATGLGSFLR
Sbjct: 1261 LGTSQEEWLVWLRFHKKKWQLQARQRLARRKRQRLESAEGVLRPGAIRDGPATGLGSFLR 1320
Query: 1321 RTARSILDLPWQIVQISETSQAGLFRLWALVGSDLHCIRLSIPRVFYVNQRVAKAEEGAS 1380
RTARSILDLPWQIVQISETSQAGLFRLWALVGSDLHCIRLSIPRVFYVNQRVAKAEEGAS
Sbjct: 1321 RTARSILDLPWQIVQISETSQAGLFRLWALVGSDLHCIRLSIPRVFYVNQRVAKAEEGAS 1380
Query: 1381 YRKVNRVLPRSNMVYNLYEYSVPEDMYQEHINEINAELSAPDIEGVYETQVPLLFRALVH 1440
YRKVNRVLPRSNMVYNLYEYSVPEDMYQEHINEINAELSAPDIEGVYETQVPLLFRALVH
Sbjct: 1381 YRKVNRVLPRSNMVYNLYEYSVPEDMYQEHINEINAELSAPDIEGVYETQVPLLFRALVH 1440
Query: 1441 LGCVCVVNKQLVRHLSGWEAETFALEHLEMRSLAQFSYLEPGSIRHIYLYHHAQAHKALF 1500
LGCVCVVNKQLVRHLSGWEAETFALEHLEMRSLAQFSYLEPGSIRHIYLYHHAQAHKALF
Sbjct: 1441 LGCVCVVNKQLVRHLSGWEAETFALEHLEMRSLAQFSYLEPGSIRHIYLYHHAQAHKALF 1500
Query: 1501 GIFIPSQRRASVFVLDTVRSNQMPSLGALYSAEHGLLLEKVGPELLPPPKHTFEVRAETD 1560
GIFIPSQRRASVFVLDTVRSNQMPSLGALYSAEHGLLLEKVGPELLPPPKHTFEVRAETD
Sbjct: 1501 GIFIPSQRRASVFVLDTVRSNQMPSLGALYSAEHGLLLEKVGPELLPPPKHTFEVRAETD 1560
Query: 1561 LKTICRAIQRFLLAYKEERRGPTLIAVQSSWELKRLASEIPVLEEFPLVPICVADKINYG 1620
LKTICRAIQRFLLAYKEERRGPTLIAVQSSWELKRLASEIPVLEEFPLVPICVADKINYG
Sbjct: 1561 LKTICRAIQRFLLAYKEERRGPTLIAVQSSWELKRLASEIPVLEEFPLVPICVADKINYG 1620
Query: 1621 VLDWQRHGARRMIRHYLNLDTCLSQAFEMSRYFHIPIGNLPEDISTFGSDLFFARHLQRH 1680
VLDWQRHGARRMIRHYLNLDTCLSQAFEMSRYFHIPIGNLPEDISTFGSDLFFARHLQRH
Sbjct: 1621 VLDWQRHGARRMIRHYLNLDTCLSQAFEMSRYFHIPIGNLPEDISTFGSDLFFARHLQRH 1680
Query: 1681 NHLLWLSPTARPDLGGKEADDNCLVMEFDDQATVEINSSGCYSTVCVELDLQNLAVNTIL 1740
NHLLWLSPTARPDLGGKEADDNCLVMEFDDQATVEINSSGCYSTVCVELDLQNLAVNTIL
Sbjct: 1681 NHLLWLSPTARPDLGGKEADDNCLVMEFDDQATVEINSSGCYSTVCVELDLQNLAVNTIL 1740
Query: 1741 QSHHVNDMEGADSMGISFDVIQQASLEDMITGGQAASAPASYDETALCSNTFRILKSMVV 1800
QSHHVNDMEGADSMGISFDVIQQASLEDMITGGQAASAPASYDETALCSNTFRILKSMVV
Sbjct: 1741 QSHHVNDMEGADSMGISFDVIQQASLEDMITGGQAASAPASYDETALCSNTFRILKSMVV 1800
Query: 1801 GWVKEITQYHNIYADNQVMHFYRWLRSPSSLLHDPALHRTLHNMMKKLFLQLIAEFKRLG 1860
GWVKEITQYHNIYADNQVMHFYRWLRSPSSLLHDPALHRTLHNMMKKLFLQLIAEFKRLG
Sbjct: 1801 GWVKEITQYHNIYADNQVMHFYRWLRSPSSLLHDPALHRTLHNMMKKLFLQLIAEFKRLG 1860
Query: 1861 SSVIYANFNRIILCTKKRRVEDAIAYVEYITSSIHSKETFHSLTISFSRCWEFLLWMDPS 1920
SSVIYANFNRIILCTKKRRVEDAIAYVEYITSSIHSKETFHSLTISFSRCWEFLLWMDPS
Sbjct: 1861 SSVIYANFNRIILCTKKRRVEDAIAYVEYITSSIHSKETFHSLTISFSRCWEFLLWMDPS 1920
Query: 1921 NYGGIKGKVSSRIHCGLQDSQKAGGAEDEQENEDDEEERDGEEEEEAEESNVEDLLENNW 1980
NYGGIKGKVSSRIHCGLQDSQKAGGAEDEQENEDDEEERDGEEEEEAEESNVEDLLENNW
Sbjct: 1921 NYGGIKGKVSSRIHCGLQDSQKAGGAEDEQENEDDEEERDGEEEEEAEESNVEDLLENNW 1980
Query: 1981 NILQFLPQAASCQNYFLMIVSAYIVAVYHCMKDGLRRSAPGSTPVRRRGASQLSQEAEGA 2040
NILQFLPQAASCQNYFLMIVSAYIVAVYHCMKDGLRRSAPGSTPVRRRGASQLSQEAEGA
Sbjct: 1981 NILQFLPQAASCQNYFLMIVSAYIVAVYHCMKDGLRRSAPGSTPVRRRGASQLSQEAEGA 2040
Query: 2041 VGALPGMITFSQDYVANELTQSFFTITQKIQKKVTGSRNSTELSEMFPVLPGSHLLLNNP 2100
VGALPGMITFSQDYVANELTQSFFTITQKIQKKVTGSRNSTELSEMFPVLPGSHLLLNNP
Sbjct: 2041 VGALPGMITFSQDYVANELTQSFFTITQKIQKKVTGSRNSTELSEMFPVLPGSHLLLNNP 2100
Query: 2101 ALEFIKYVCKVLSLDTNITNQVNKLNRDLLRLVDVGEFSEEAQFRDPCRSYVLPEVICRS 2160
ALEFIKYVCKVLSLDTNITNQVNKLNRDLLRLVDVGEFSEEAQFRDPCRSYVLPEVICRS
Sbjct: 2101 ALEFIKYVCKVLSLDTNITNQVNKLNRDLLRLVDVGEFSEEAQFRDPCRSYVLPEVICRS 2160
Query: 2161 CNFCRDLDLCKDSSFSEDGAVLPQWLCSNCQAPYDSSAIEMTLVEVLQKKLMAFTLQDLV 2220
CNFCRDLDLCKDSSFSEDGAVLPQWLCSNCQAPYDSSAIEMTLVEVLQKKLMAFTLQDLV
Sbjct: 2161 CNFCRDLDLCKDSSFSEDGAVLPQWLCSNCQAPYDSSAIEMTLVEVLQKKLMAFTLQDLV 2220
Query: 2221 CLKCRGVKETSMPVYCSCAGDFALTIHTQVFMEQIGIFRNIAQHYGMSYLLETLEWLLQK 2280
CLKCRGVKETSMPVYCSCAGDFALTIHTQVFMEQIGIFRNIAQHYGMSYLLETLEWLLQK
Sbjct: 2221 CLKCRGVKETSMPVYCSCAGDFALTIHTQVFMEQIGIFRNIAQHYGMSYLLETLEWLLQK 2280
Query: 2281 NPQLGH 2286
NPQLGH
Sbjct: 2281 NPQLGH 2286
>gi|106507301 DNA-directed DNA polymerase alpha 1 [Homo sapiens]
Length = 1462
Score = 48.9 bits (115), Expect = 6e-05
Identities = 73/304 (24%), Positives = 128/304 (42%), Gaps = 64/304 (21%)
Query: 801 YDSLQLAHKCILNSFYGYVMRKGARWYSMEMAGIVCFTGANIITQARELIEQIGRPLEL- 859
YD Q A K NS YG + +R+Y+ +A +V + G I+ +E+++++ LE+
Sbjct: 942 YDIRQKALKLTANSMYGCLGFSYSRFYAKPLAALVTYKGREILMHTKEMVQKMN--LEVI 999
Query: 860 --DTDGIWCVLPNSFPENFVFKTTNVKKPKVTISYPGAMLNIMVKEGFTNDQYQELAEPS 917
DTD I + NS VFK N K +V N Y+ L
Sbjct: 1000 YGDTDSI-MINTNSTNLEEVFKLGNKVKSEV------------------NKLYKLLE--- 1037
Query: 918 SLTYVTRSENSIFFEVDGPYLAMILPASKEEGKKLKKRYAVF----NEDGSLA---ELKG 970
++DG + +++L KK+YA DG+ ELKG
Sbjct: 1038 -------------IDIDGVFKSLLL--------LKKKKYAALVVEPTSDGNYVTKQELKG 1076
Query: 971 FEVKRRGELQLIKIFQSSVFEAFLKGSTLEEVYGSVAK-VADYWLDVLYSKAANMPDSEL 1029
++ RR L K + V L + + + ++ K + + +VL ++P S+
Sbjct: 1077 LDIVRRDWCDLAKDTGNFVIGQILSDQSRDTIVENIQKRLIEIGENVL---NGSVPVSQ- 1132
Query: 1030 FELISENRSMSRKLEDYGEQKSTSISTAKRLAEFLGDQMVKDAGLSCRYIISRKPEGSPV 1089
FE+ N+++++ +DY ++KS G + VK AG + Y+I +
Sbjct: 1133 FEI---NKALTKDPQDYPDKKSLPHVHVALWINSQGGRKVK-AGDTVSYVICQDGSNLTA 1188
Query: 1090 TERA 1093
++RA
Sbjct: 1189 SQRA 1192
Score = 33.9 bits (76), Expect = 1.9
Identities = 72/338 (21%), Positives = 119/338 (35%), Gaps = 47/338 (13%)
Query: 254 PVEITRRDDLVERPDPVVLAFDIETTKLPLKFPDAETDQIMMISYMIDGQGYLITNREIV 313
PV + + + +PD V + D+ L + +T Q + Q +I +V
Sbjct: 510 PVSWCKVEAMALKPDLVNVIKDVSPPPLVVMAFSMKTMQNAK-----NHQNEIIAMAALV 564
Query: 314 SEDIEDFEFTPKPEYEGPFCVFNEP------------------------DEAHLIQRWFE 349
+ PKP ++ FCV ++P E L+ +
Sbjct: 565 HHSFALDKAAPKPPFQSHFCVVSKPKDCIFPYAFKEVIEKKNVKVEVAATERTLLGFFLA 624
Query: 350 HVQETKPTIMVTYNGDFFDWPFVEARAAVHGLSMQQEIGFQKDSQ----------GEYKA 399
V + P I+V +N F+ + R V +IG K S GE A
Sbjct: 625 KVHKIDPDIIVGHNIYGFELEVLLQRINVCKAPHWSKIGRLKRSNMPKLGGRSGFGERNA 684
Query: 400 PQCIHMDCLRWVKRDSYLPVGSHNLKAAAKAKLGYDPVELDPEDMCRMATEQPQTLATYS 459
C M C + + S++L + L + V + E++ M +E Q L
Sbjct: 685 -TCGRMICDVEISAKELIRCKSYHLSELVQQILKTERVVIPMENIQNMYSESSQLLYLLE 743
Query: 460 VSDAVATYYLYMK---YVHPFIFALCTIIPMEPDEVLRKGSGTLCEALLMVQAFHANIIF 516
+ A + L + V P + I L G E LL+ + N I
Sbjct: 744 HTWKDAKFILQIMCELNVLPLALQITNIAGNIMSRTLMGGRSERNEFLLLHAFYENNYIV 803
Query: 517 PNKQ--EQEFNKLTDDGHVLDSET--YVGGHVEALESG 550
P+KQ + KL D+ +D +T Y G +A +G
Sbjct: 804 PDKQIFRKPQQKLGDEDEEIDGDTNKYKKGRKKAAYAG 841
>gi|115511012 coiled-coil domain containing 136 [Homo sapiens]
Length = 1154
Score = 42.0 bits (97), Expect = 0.007
Identities = 17/40 (42%), Positives = 28/40 (70%)
Query: 1939 DSQKAGGAEDEQENEDDEEERDGEEEEEAEESNVEDLLEN 1978
D ++A ED++ENE+D+EE + EE+ E EE + + LE+
Sbjct: 1068 DPEEAKSTEDQEENEEDKEEEEKEEDSEEEEDDADSSLES 1107
Score = 32.3 bits (72), Expect = 5.5
Identities = 15/47 (31%), Positives = 25/47 (53%)
Query: 1928 KVSSRIHCGLQDSQKAGGAEDEQENEDDEEERDGEEEEEAEESNVED 1974
K ++ CG + + E+ + ED EE + +EEEE EE + E+
Sbjct: 1051 KEEAKEQCGDELVAEPADPEEAKSTEDQEENEEDKEEEEKEEDSEEE 1097
>gi|86262149 zinc finger and BTB domain containing 7C [Homo sapiens]
Length = 619
Score = 42.0 bits (97), Expect = 0.007
Identities = 17/31 (54%), Positives = 24/31 (77%)
Query: 1944 GGAEDEQENEDDEEERDGEEEEEAEESNVED 1974
GG ED++E++DD+E+ D EE+EE EE ED
Sbjct: 133 GGEEDDKEDDDDDEDDDDEEDEEEEEEEEED 163
Score = 38.1 bits (87), Expect = 0.100
Identities = 16/36 (44%), Positives = 24/36 (66%)
Query: 1939 DSQKAGGAEDEQENEDDEEERDGEEEEEAEESNVED 1974
D + ED+ ++EDD++E D EEEEE EE + +D
Sbjct: 132 DGGEEDDKEDDDDDEDDDDEEDEEEEEEEEEDDDDD 167
Score = 33.1 bits (74), Expect = 3.2
Identities = 13/36 (36%), Positives = 23/36 (63%)
Query: 1939 DSQKAGGAEDEQENEDDEEERDGEEEEEAEESNVED 1974
D + EDE+E E++EE+ D + E+ A++ N+ D
Sbjct: 144 DDEDDDDEEDEEEEEEEEEDDDDDTEDFADQENLPD 179
Score = 32.7 bits (73), Expect = 4.2
Identities = 12/38 (31%), Positives = 23/38 (60%)
Query: 1937 LQDSQKAGGAEDEQENEDDEEERDGEEEEEAEESNVED 1974
L+ + G +E + EDD+++ D ++EE+ EE E+
Sbjct: 124 LEIMEPGGDGGEEDDKEDDDDDEDDDDEEDEEEEEEEE 161
Score = 32.7 bits (73), Expect = 4.2
Identities = 19/57 (33%), Positives = 33/57 (57%), Gaps = 5/57 (8%)
Query: 1936 GLQDSQKAGGAEDEQENEDDEEERDGEEEEEAEESNVEDLLENNWNILQFLPQAASC 1992
G +D ++ +++ ++E+DEEE EEEEE ++ + ED + N+ PQ SC
Sbjct: 134 GEEDDKEDDDDDEDDDDEEDEEEE--EEEEEDDDDDTEDFADQE-NLPD--PQDISC 185
>gi|151101407 prothymosin, alpha isoform 1 [Homo sapiens]
Length = 111
Score = 41.2 bits (95), Expect = 0.012
Identities = 17/43 (39%), Positives = 29/43 (67%)
Query: 1937 LQDSQKAGGAEDEQENEDDEEERDGEEEEEAEESNVEDLLENN 1979
+ + ++ GG E+E+E E D EE DG+E+EEAE + + E++
Sbjct: 53 VDEEEEEGGEEEEEEEEGDGEEEDGDEDEEAESATGKRAAEDD 95
Score = 35.8 bits (81), Expect = 0.50
Identities = 19/44 (43%), Positives = 26/44 (59%), Gaps = 7/44 (15%)
Query: 1938 QDSQKAGGAEDEQENE-------DDEEERDGEEEEEAEESNVED 1974
+D+ G AE+E+ E D+EEE GEEEEE EE + E+
Sbjct: 31 RDAPANGNAENEENGEQEADNEVDEEEEEGGEEEEEEEEGDGEE 74
>gi|151101404 prothymosin, alpha isoform 2 [Homo sapiens]
Length = 110
Score = 41.2 bits (95), Expect = 0.012
Identities = 17/43 (39%), Positives = 29/43 (67%)
Query: 1937 LQDSQKAGGAEDEQENEDDEEERDGEEEEEAEESNVEDLLENN 1979
+ + ++ GG E+E+E E D EE DG+E+EEAE + + E++
Sbjct: 52 VDEEEEEGGEEEEEEEEGDGEEEDGDEDEEAESATGKRAAEDD 94
Score = 34.3 bits (77), Expect = 1.4
Identities = 17/29 (58%), Positives = 21/29 (72%), Gaps = 1/29 (3%)
Query: 1947 EDEQENE-DDEEERDGEEEEEAEESNVED 1974
E E +NE D+EEE GEEEEE EE + E+
Sbjct: 45 EQEADNEVDEEEEEGGEEEEEEEEGDGEE 73
>gi|58761548 tau tubulin kinase 1 [Homo sapiens]
Length = 1321
Score = 40.4 bits (93), Expect = 0.020
Identities = 17/33 (51%), Positives = 24/33 (72%)
Query: 1942 KAGGAEDEQENEDDEEERDGEEEEEAEESNVED 1974
+A G E+E+E E+DEEE + +EEEE EE E+
Sbjct: 728 QANGKEEEEEEEEDEEEEEEDEEEEEEEEEEEE 760
Score = 40.0 bits (92), Expect = 0.026
Identities = 18/34 (52%), Positives = 23/34 (67%)
Query: 1941 QKAGGAEDEQENEDDEEERDGEEEEEAEESNVED 1974
Q G E+E+E ED+EEE + EEEEE EE E+
Sbjct: 728 QANGKEEEEEEEEDEEEEEEDEEEEEEEEEEEEE 761
Score = 39.3 bits (90), Expect = 0.045
Identities = 17/28 (60%), Positives = 21/28 (75%)
Query: 1947 EDEQENEDDEEERDGEEEEEAEESNVED 1974
EDE+E E+DEEE + EEEEE EE E+
Sbjct: 740 EDEEEEEEDEEEEEEEEEEEEEEEEEEE 767
Score = 37.4 bits (85), Expect = 0.17
Identities = 15/37 (40%), Positives = 26/37 (70%)
Query: 1938 QDSQKAGGAEDEQENEDDEEERDGEEEEEAEESNVED 1974
++ ++ E+E+E+E++EEE + EEEEE EE E+
Sbjct: 734 EEEEEEEDEEEEEEDEEEEEEEEEEEEEEEEEEEEEE 770
Score = 36.6 bits (83), Expect = 0.29
Identities = 15/39 (38%), Positives = 26/39 (66%)
Query: 1936 GLQDSQKAGGAEDEQENEDDEEERDGEEEEEAEESNVED 1974
G ++ ++ E+E+E +++EEE + EEEEE EE E+
Sbjct: 731 GKEEEEEEEEDEEEEEEDEEEEEEEEEEEEEEEEEEEEE 769
Score = 36.2 bits (82), Expect = 0.38
Identities = 15/33 (45%), Positives = 24/33 (72%)
Query: 1938 QDSQKAGGAEDEQENEDDEEERDGEEEEEAEES 1970
+D ++ E+E+E E++EEE + EEEEE EE+
Sbjct: 740 EDEEEEEEDEEEEEEEEEEEEEEEEEEEEEEEA 772
Score = 35.8 bits (81), Expect = 0.50
Identities = 14/37 (37%), Positives = 25/37 (67%)
Query: 1938 QDSQKAGGAEDEQENEDDEEERDGEEEEEAEESNVED 1974
++ ++ E+E++ E++EEE + EEEEE EE E+
Sbjct: 735 EEEEEEDEEEEEEDEEEEEEEEEEEEEEEEEEEEEEE 771
Score = 33.5 bits (75), Expect = 2.5
Identities = 13/34 (38%), Positives = 22/34 (64%)
Query: 1941 QKAGGAEDEQENEDDEEERDGEEEEEAEESNVED 1974
Q ++E+E E+++EE + E+EEE EE E+
Sbjct: 726 QPQANGKEEEEEEEEDEEEEEEDEEEEEEEEEEE 759
>gi|100816397 MYST histone acetyltransferase (monocytic leukemia) 4
[Homo sapiens]
Length = 2073
Score = 40.4 bits (93), Expect = 0.020
Identities = 18/50 (36%), Positives = 29/50 (58%)
Query: 1925 IKGKVSSRIHCGLQDSQKAGGAEDEQENEDDEEERDGEEEEEAEESNVED 1974
+ G+ + + S++ EDE+E E++EEE + EEEEE EE E+
Sbjct: 1054 VTGERGQLLELSKESSEEEEEEEDEEEEEEEEEEEEDEEEEEEEEEEEEE 1103
Score = 39.3 bits (90), Expect = 0.045
Identities = 20/58 (34%), Positives = 31/58 (53%)
Query: 1937 LQDSQKAGGAEDEQENEDDEEERDGEEEEEAEESNVEDLLENNWNILQFLPQAASCQN 1994
L + K E+E+E +++EEE + EEEE+ EE E+ E NI P+ Q+
Sbjct: 1061 LLELSKESSEEEEEEEDEEEEEEEEEEEEDEEEEEEEEEEEEEENIQSSPPRLTKPQS 1118
Score = 32.3 bits (72), Expect = 5.5
Identities = 16/29 (55%), Positives = 21/29 (72%), Gaps = 2/29 (6%)
Query: 1947 EDEQENEDDEEERDGEEEEEAEE--SNVE 1973
E+E+E E++EEE + EEE E EE NVE
Sbjct: 1351 EEEEEEEEEEEEEEEEEEGEEEEGGGNVE 1379
>gi|209862789 microtubule associated monoxygenase, calponin and LIM
domain containing 3 isoform 1 [Homo sapiens]
Length = 2002
Score = 40.4 bits (93), Expect = 0.020
Identities = 26/80 (32%), Positives = 43/80 (53%), Gaps = 8/80 (10%)
Query: 1917 MDPSNYGGIKGKVSSRIHCGLQ-------DSQKAGGAEDEQENEDDEEERDGEEEEEAEE 1969
+ PS+ GG+ K + RIH L+ ++ K+ G +E+E E++EEE + EEEE+ +E
Sbjct: 953 LPPSDLGGVPWKEAVRIHALLKGKSEEELEASKSFGPGNEEE-EEEEEEYEEEEEEDYDE 1011
Query: 1970 SNVEDLLENNWNILQFLPQA 1989
E N + Q + A
Sbjct: 1012 EEEESSEAGNQRLQQVMHAA 1031
>gi|4759128 solute carrier family 24 (sodium/potassium/calcium
exchanger), member 1 [Homo sapiens]
Length = 1099
Score = 39.7 bits (91), Expect = 0.034
Identities = 16/39 (41%), Positives = 26/39 (66%)
Query: 1936 GLQDSQKAGGAEDEQENEDDEEERDGEEEEEAEESNVED 1974
G++D + G + E+E E++EE+ + EEEEE EE E+
Sbjct: 847 GVEDGGGSDGGDSEEEEEEEEEQEEEEEEEEQEEEEEEE 885
Score = 39.3 bits (90), Expect = 0.045
Identities = 20/44 (45%), Positives = 29/44 (65%), Gaps = 2/44 (4%)
Query: 1939 DSQKAGGAEDEQENEDDEEERDGEEEEEAEESNV--EDLLENNW 1980
DS++ E+EQE E++EEE++ EEEEE EE E+ L +W
Sbjct: 858 DSEEEEEEEEEQEEEEEEEEQEEEEEEEEEEEEKGNEEPLSLDW 901
Score = 37.0 bits (84), Expect = 0.22
Identities = 16/38 (42%), Positives = 24/38 (63%)
Query: 1944 GGAEDEQENEDDEEERDGEEEEEAEESNVEDLLENNWN 1981
GG +E+E E++E+E + EEEE+ EE E+ E N
Sbjct: 856 GGDSEEEEEEEEEQEEEEEEEEQEEEEEEEEEEEEKGN 893
Score = 35.8 bits (81), Expect = 0.50
Identities = 18/58 (31%), Positives = 29/58 (50%)
Query: 1917 MDPSNYGGIKGKVSSRIHCGLQDSQKAGGAEDEQENEDDEEERDGEEEEEAEESNVED 1974
+ N+G K G D + E+E+E +++EEE + +EEEE EE E+
Sbjct: 833 LSAENHGEAKNDEKGVEDGGGSDGGDSEEEEEEEEEQEEEEEEEEQEEEEEEEEEEEE 890
>gi|118600967 shroom family member 4 [Homo sapiens]
Length = 1493
Score = 39.3 bits (90), Expect = 0.045
Identities = 18/36 (50%), Positives = 24/36 (66%)
Query: 1938 QDSQKAGGAEDEQENEDDEEERDGEEEEEAEESNVE 1973
Q Q+ E+E+E E++EEE + EEEEEAEE E
Sbjct: 1123 QQQQQQKQQEEEEEEEEEEEEEEEEEEEEAEEEEEE 1158
Score = 35.8 bits (81), Expect = 0.50
Identities = 16/35 (45%), Positives = 22/35 (62%)
Query: 1938 QDSQKAGGAEDEQENEDDEEERDGEEEEEAEESNV 1972
Q QK E+E+E E++EEE + EEE E EE +
Sbjct: 1125 QQQQKQQEEEEEEEEEEEEEEEEEEEEAEEEEEEL 1159
Score = 35.0 bits (79), Expect = 0.85
Identities = 15/37 (40%), Positives = 24/37 (64%)
Query: 1938 QDSQKAGGAEDEQENEDDEEERDGEEEEEAEESNVED 1974
Q Q+ + ++E E++EEE + EEEEE EE+ E+
Sbjct: 1120 QQKQQQQQQKQQEEEEEEEEEEEEEEEEEEEEAEEEE 1156
Score = 34.7 bits (78), Expect = 1.1
Identities = 15/38 (39%), Positives = 24/38 (63%)
Query: 1938 QDSQKAGGAEDEQENEDDEEERDGEEEEEAEESNVEDL 1975
+ Q+ ++E+E E++EEE + EEEEE E E+L
Sbjct: 1122 KQQQQQQKQQEEEEEEEEEEEEEEEEEEEEAEEEEEEL 1159
Score = 34.3 bits (77), Expect = 1.4
Identities = 16/43 (37%), Positives = 25/43 (58%)
Query: 1932 RIHCGLQDSQKAGGAEDEQENEDDEEERDGEEEEEAEESNVED 1974
R+ Q ++ + +QE E++EEE + EEEEE EE E+
Sbjct: 1113 RLFRAAQQQKQQQQQQKQQEEEEEEEEEEEEEEEEEEEEAEEE 1155
Score = 33.9 bits (76), Expect = 1.9
Identities = 16/39 (41%), Positives = 23/39 (58%)
Query: 1938 QDSQKAGGAEDEQENEDDEEERDGEEEEEAEESNVEDLL 1976
Q Q+ + E+E E++EEE + EEEEE E E+ L
Sbjct: 1121 QKQQQQQQKQQEEEEEEEEEEEEEEEEEEEEAEEEEEEL 1159
Score = 31.6 bits (70), Expect = 9.4
Identities = 13/31 (41%), Positives = 20/31 (64%)
Query: 1947 EDEQENEDDEEERDGEEEEEAEESNVEDLLE 1977
+ +Q+ + +EEE + EEEEE EE E+ E
Sbjct: 1124 QQQQQKQQEEEEEEEEEEEEEEEEEEEEAEE 1154
>gi|113204617 skeletal muscle ryanodine receptor isoform 2 [Homo
sapiens]
Length = 5033
Score = 39.3 bits (90), Expect = 0.045
Identities = 26/68 (38%), Positives = 38/68 (55%), Gaps = 9/68 (13%)
Query: 1938 QDSQKAGGAEDEQENEDDEEER------DGEEEEEAEESNVEDLLENNWNILQF-LPQAA 1990
+D ++ G EDE+E E+DEEE + +EEEEA E E+ LE +LQ LP++
Sbjct: 1878 EDEEEEGEEEDEEEKEEDEEETAQEKEDEEKEEEEAAEGEKEEGLEE--GLLQMKLPESV 1935
Query: 1991 SCQNYFLM 1998
Q L+
Sbjct: 1936 KLQMCHLL 1943
Score = 33.5 bits (75), Expect = 2.5
Identities = 15/30 (50%), Positives = 20/30 (66%)
Query: 1948 DEQENEDDEEERDGEEEEEAEESNVEDLLE 1977
+E+E ED+EEE + E+EEE EE E E
Sbjct: 1873 EEEEEEDEEEEGEEEDEEEKEEDEEETAQE 1902
Score = 31.6 bits (70), Expect = 9.4
Identities = 12/28 (42%), Positives = 20/28 (71%)
Query: 1947 EDEQENEDDEEERDGEEEEEAEESNVED 1974
E+E++ E++ EE D EE+EE EE ++
Sbjct: 1875 EEEEDEEEEGEEEDEEEKEEDEEETAQE 1902
>gi|113204615 skeletal muscle ryanodine receptor isoform 1 [Homo
sapiens]
Length = 5038
Score = 39.3 bits (90), Expect = 0.045
Identities = 26/68 (38%), Positives = 38/68 (55%), Gaps = 9/68 (13%)
Query: 1938 QDSQKAGGAEDEQENEDDEEER------DGEEEEEAEESNVEDLLENNWNILQF-LPQAA 1990
+D ++ G EDE+E E+DEEE + +EEEEA E E+ LE +LQ LP++
Sbjct: 1878 EDEEEEGEEEDEEEKEEDEEETAQEKEDEEKEEEEAAEGEKEEGLEE--GLLQMKLPESV 1935
Query: 1991 SCQNYFLM 1998
Q L+
Sbjct: 1936 KLQMCHLL 1943
Score = 33.5 bits (75), Expect = 2.5
Identities = 15/30 (50%), Positives = 20/30 (66%)
Query: 1948 DEQENEDDEEERDGEEEEEAEESNVEDLLE 1977
+E+E ED+EEE + E+EEE EE E E
Sbjct: 1873 EEEEEEDEEEEGEEEDEEEKEEDEEETAQE 1902
Score = 31.6 bits (70), Expect = 9.4
Identities = 12/28 (42%), Positives = 20/28 (71%)
Query: 1947 EDEQENEDDEEERDGEEEEEAEESNVED 1974
E+E++ E++ EE D EE+EE EE ++
Sbjct: 1875 EEEEDEEEEGEEEDEEEKEEDEEETAQE 1902
>gi|227496440 multiple C2 domains, transmembrane 2 isoform 1 [Homo
sapiens]
Length = 878
Score = 38.9 bits (89), Expect = 0.059
Identities = 37/148 (25%), Positives = 72/148 (48%), Gaps = 29/148 (19%)
Query: 1851 QLIAEFKRLGSSVIYANFNRIILCTKKRRVEDAI-AYVEYITSSIHSKETFHSLTISFS- 1908
+ + + ++L ++ + +R+ +R+ AI ++++ S + T S TI+F+
Sbjct: 644 RFVEDSRKLSKKILSRDVDRV------KRITMAIWNTMQFLKSCFQWESTLRS-TIAFAV 696
Query: 1909 ---RCWEFLLWMDP---------SNYGGIKGKVSSRIHCGLQDSQKAGGAEDEQENEDDE 1956
W F L+M P + +KGKVSS +QDSQ++ +DE++ +D E
Sbjct: 697 FLITVWNFELYMIPLALLLIFVYNFIRPVKGKVSS-----IQDSQESTDIDDEEDEDDKE 751
Query: 1957 EERDGEEEEEAEESNVEDLLENNWNILQ 1984
E+ G E V+D++ N+L+
Sbjct: 752 SEKKGLIE---RIYMVQDIVSTVQNVLE 776
>gi|118498345 AT-binding transcription factor 1 [Homo sapiens]
Length = 3703
Score = 38.9 bits (89), Expect = 0.059
Identities = 18/35 (51%), Positives = 24/35 (68%)
Query: 1940 SQKAGGAEDEQENEDDEEERDGEEEEEAEESNVED 1974
S+K AE+E E E++EEE + EEEEE EE E+
Sbjct: 453 SEKVEPAEEEAEEEEEEEEAEEEEEEEEEEEEEEE 487
Score = 34.7 bits (78), Expect = 1.1
Identities = 15/26 (57%), Positives = 20/26 (76%)
Query: 1946 AEDEQENEDDEEERDGEEEEEAEESN 1971
AE+E+E E+ EEE + EEEEE EE +
Sbjct: 463 AEEEEEEEEAEEEEEEEEEEEEEEED 488
Score = 33.1 bits (74), Expect = 3.2
Identities = 14/29 (48%), Positives = 22/29 (75%)
Query: 1941 QKAGGAEDEQENEDDEEERDGEEEEEAEE 1969
++A E+E+E E++EEE + EEEEE +E
Sbjct: 461 EEAEEEEEEEEAEEEEEEEEEEEEEEEDE 489
Score = 32.7 bits (73), Expect = 4.2
Identities = 13/39 (33%), Positives = 25/39 (64%)
Query: 1937 LQDSQKAGGAEDEQENEDDEEERDGEEEEEAEESNVEDL 1975
++ +++ E+E+E ++EEE + EEEEE E+ + L
Sbjct: 456 VEPAEEEAEEEEEEEEAEEEEEEEEEEEEEEEDEGCKGL 494
>gi|17975763 myelin transcription factor 1 [Homo sapiens]
Length = 1121
Score = 38.5 bits (88), Expect = 0.077
Identities = 19/49 (38%), Positives = 29/49 (59%)
Query: 1926 KGKVSSRIHCGLQDSQKAGGAEDEQENEDDEEERDGEEEEEAEESNVED 1974
KG +S ++ ++ EDE+E E++EEE + EEEEE EE E+
Sbjct: 252 KGILSHEEEDEEEEEEEEEEEEDEEEEEEEEEEEEEEEEEEEEEEEEEE 300
Score = 37.0 bits (84), Expect = 0.22
Identities = 15/37 (40%), Positives = 25/37 (67%)
Query: 1938 QDSQKAGGAEDEQENEDDEEERDGEEEEEAEESNVED 1974
++ ++ E+E+E E++EEE + EEEEE EE E+
Sbjct: 267 EEEEEEEDEEEEEEEEEEEEEEEEEEEEEEEEEEEEE 303
Score = 37.0 bits (84), Expect = 0.22
Identities = 15/37 (40%), Positives = 25/37 (67%)
Query: 1938 QDSQKAGGAEDEQENEDDEEERDGEEEEEAEESNVED 1974
++ ++ E+E+E E++EEE + EEEEE EE E+
Sbjct: 268 EEEEEEDEEEEEEEEEEEEEEEEEEEEEEEEEEEEEE 304
Score = 36.6 bits (83), Expect = 0.29
Identities = 15/30 (50%), Positives = 22/30 (73%)
Query: 1947 EDEQENEDDEEERDGEEEEEAEESNVEDLL 1976
E+E+E E++EEE + EEEEE EE D++
Sbjct: 283 EEEEEEEEEEEEEEEEEEEEEEEEAAPDVI 312
Score = 36.2 bits (82), Expect = 0.38
Identities = 15/28 (53%), Positives = 21/28 (75%)
Query: 1947 EDEQENEDDEEERDGEEEEEAEESNVED 1974
E+E+E E++EEE + EEEEE EE E+
Sbjct: 278 EEEEEEEEEEEEEEEEEEEEEEEEEEEE 305
Score = 36.2 bits (82), Expect = 0.38
Identities = 15/28 (53%), Positives = 21/28 (75%)
Query: 1947 EDEQENEDDEEERDGEEEEEAEESNVED 1974
E+E+E E++EEE + EEEEE EE E+
Sbjct: 279 EEEEEEEEEEEEEEEEEEEEEEEEEEEE 306
Score = 35.4 bits (80), Expect = 0.65
Identities = 15/37 (40%), Positives = 25/37 (67%)
Query: 1938 QDSQKAGGAEDEQENEDDEEERDGEEEEEAEESNVED 1974
+ S++ G E+E+E++EEE + EEE+E EE E+
Sbjct: 247 ESSKQKGILSHEEEDEEEEEEEEEEEEDEEEEEEEEE 283
Score = 35.4 bits (80), Expect = 0.65
Identities = 14/37 (37%), Positives = 25/37 (67%)
Query: 1938 QDSQKAGGAEDEQENEDDEEERDGEEEEEAEESNVED 1974
++ ++ ++E+E E++EEE + EEEEE EE E+
Sbjct: 265 EEEEEEEEEDEEEEEEEEEEEEEEEEEEEEEEEEEEE 301
Score = 35.0 bits (79), Expect = 0.85
Identities = 14/33 (42%), Positives = 24/33 (72%)
Query: 1938 QDSQKAGGAEDEQENEDDEEERDGEEEEEAEES 1970
++ ++ E+E+E E++EEE + EEEEE EE+
Sbjct: 275 EEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEA 307
Score = 33.9 bits (76), Expect = 1.9
Identities = 14/37 (37%), Positives = 23/37 (62%)
Query: 1938 QDSQKAGGAEDEQENEDDEEERDGEEEEEAEESNVED 1974
++S K G +E +++EEE + EEEE+ EE E+
Sbjct: 246 EESSKQKGILSHEEEDEEEEEEEEEEEEDEEEEEEEE 282
Score = 31.6 bits (70), Expect = 9.4
Identities = 13/35 (37%), Positives = 23/35 (65%)
Query: 1938 QDSQKAGGAEDEQENEDDEEERDGEEEEEAEESNV 1972
++ ++ E+E+E E++EEE + EEEEE +V
Sbjct: 277 EEEEEEEEEEEEEEEEEEEEEEEEEEEEEEAAPDV 311
>gi|154759293 cysteine-rich hydrophobic domain 1 [Homo sapiens]
Length = 224
Score = 38.5 bits (88), Expect = 0.077
Identities = 16/34 (47%), Positives = 23/34 (67%)
Query: 1940 SQKAGGAEDEQENEDDEEERDGEEEEEAEESNVE 1973
S G +D++E+E++EEE + EEEEE EE E
Sbjct: 35 SSSVSGPDDDEEDEEEEEEEEEEEEEEEEEEEEE 68
Score = 36.2 bits (82), Expect = 0.38
Identities = 15/24 (62%), Positives = 20/24 (83%)
Query: 1947 EDEQENEDDEEERDGEEEEEAEES 1970
EDE+E E++EEE + EEEEE EE+
Sbjct: 46 EDEEEEEEEEEEEEEEEEEEEEEA 69
>gi|22035679 AT rich interactive domain 4B isoform 2 [Homo sapiens]
Length = 1226
Score = 38.5 bits (88), Expect = 0.077
Identities = 20/50 (40%), Positives = 29/50 (58%), Gaps = 2/50 (4%)
Query: 1937 LQDSQKAGGAEDEQENEDDEEERDGEEEEEAEESNVEDLLENNWNILQFL 1986
L++ + AE+E+E EDDE+E++ EE EE +E E N LQ L
Sbjct: 269 LKEDSSSSEAEEEEEEEDDEKEKEDNSSEEEEE--IEPFPEERENFLQQL 316
>gi|22035677 AT rich interactive domain 4B isoform 1 [Homo sapiens]
Length = 1312
Score = 38.5 bits (88), Expect = 0.077
Identities = 20/50 (40%), Positives = 29/50 (58%), Gaps = 2/50 (4%)
Query: 1937 LQDSQKAGGAEDEQENEDDEEERDGEEEEEAEESNVEDLLENNWNILQFL 1986
L++ + AE+E+E EDDE+E++ EE EE +E E N LQ L
Sbjct: 269 LKEDSSSSEAEEEEEEEDDEKEKEDNSSEEEEE--IEPFPEERENFLQQL 316
Score = 38.5 bits (88), Expect = 0.077
Identities = 18/42 (42%), Positives = 28/42 (66%), Gaps = 2/42 (4%)
Query: 1938 QDSQKAGGAEDEQENEDDEEERDGEEEEEAEESNVEDLLENN 1979
++ K+G +++E+EDDEE + EEEEE EE +D +NN
Sbjct: 522 EEKAKSGDETNKEEDEDDEEAEEEEEEEEEEEDEDDD--DNN 561
Score = 36.6 bits (83), Expect = 0.29
Identities = 29/113 (25%), Positives = 51/113 (45%), Gaps = 8/113 (7%)
Query: 1870 RIILCTKKRRVEDAIAYVEYITSSIHSKETFHSLTISFSRCWEFLLWMDPSNYGGIKGK- 1928
R I+ +++ +ED I E I S+ SK+ + S + + P + + K
Sbjct: 445 RNIIPREEKPIEDEIERKENIKPSLGSKKNLLESIPTHSDQEKEVNIKKPEDNENLDDKD 504
Query: 1929 -------VSSRIHCGLQDSQKAGGAEDEQENEDDEEERDGEEEEEAEESNVED 1974
S I ++ + G E +E ++D+EE + EEEEE EE + +D
Sbjct: 505 DDTTRVDESLNIKVEAEEEKAKSGDETNKEEDEDDEEAEEEEEEEEEEEDEDD 557
Score = 34.7 bits (78), Expect = 1.1
Identities = 14/31 (45%), Positives = 22/31 (70%)
Query: 1938 QDSQKAGGAEDEQENEDDEEERDGEEEEEAE 1968
+D ++A E+E+E E+DE++ D EEEE E
Sbjct: 537 EDDEEAEEEEEEEEEEEDEDDDDNNEEEEFE 567
Score = 34.3 bits (77), Expect = 1.4
Identities = 13/31 (41%), Positives = 24/31 (77%)
Query: 1947 EDEQENEDDEEERDGEEEEEAEESNVEDLLE 1977
ED++E E++EEE + EE+E+ +++N E+ E
Sbjct: 537 EDDEEAEEEEEEEEEEEDEDDDDNNEEEEFE 567
>gi|211904182 DDB1 and CUL4 associated factor 8-like 2 [Homo sapiens]
Length = 631
Score = 38.1 bits (87), Expect = 0.100
Identities = 15/31 (48%), Positives = 24/31 (77%)
Query: 1938 QDSQKAGGAEDEQENEDDEEERDGEEEEEAE 1968
++ Q+ GG E+E+E E++EEE + EEEEE +
Sbjct: 118 EEIQEEGGEEEEEEEEEEEEEEEEEEEEEEQ 148
Score = 33.5 bits (75), Expect = 2.5
Identities = 15/31 (48%), Positives = 20/31 (64%)
Query: 1944 GGAEDEQENEDDEEERDGEEEEEAEESNVED 1974
G E E+E ED+E + +G EEEE EE E+
Sbjct: 107 GEEETEREEEDEEIQEEGGEEEEEEEEEEEE 137
Score = 32.3 bits (72), Expect = 5.5
Identities = 15/39 (38%), Positives = 24/39 (61%)
Query: 1936 GLQDSQKAGGAEDEQENEDDEEERDGEEEEEAEESNVED 1974
G +++++ E+ QE +EEE + EEEEE EE E+
Sbjct: 107 GEEETEREEEDEEIQEEGGEEEEEEEEEEEEEEEEEEEE 145
>gi|56711320 hypothetical protein LOC145407 [Homo sapiens]
Length = 774
Score = 38.1 bits (87), Expect = 0.100
Identities = 17/50 (34%), Positives = 29/50 (58%)
Query: 1928 KVSSRIHCGLQDSQKAGGAEDEQENEDDEEERDGEEEEEAEESNVEDLLE 1977
+V++ GL + G EDE E ++++E+ + E+EEE EE D L+
Sbjct: 595 RVNTAASYGLDQLESEEGQEDEDEEDEEDEDEEEEDEEEDEEDKDADSLD 644
>gi|124244056 family with sequence similarity 123B [Homo sapiens]
Length = 1135
Score = 37.7 bits (86), Expect = 0.13
Identities = 17/42 (40%), Positives = 25/42 (59%)
Query: 1947 EDEQENEDDEEERDGEEEEEAEESNVEDLLENNWNILQFLPQ 1988
+D++E E++EE EEEEE +E +D LE W Q P+
Sbjct: 377 DDDEEEEEEEEVELEEEEEEVKEEEEDDDLEYLWETAQMYPR 418
>gi|4503257 death-domain associated protein isoform a [Homo sapiens]
Length = 740
Score = 37.7 bits (86), Expect = 0.13
Identities = 16/31 (51%), Positives = 25/31 (80%)
Query: 1947 EDEQENEDDEEERDGEEEEEAEESNVEDLLE 1977
ED++E++++EEE + EEEEEA +S E+ LE
Sbjct: 438 EDDEESDEEEEEEEEEEEEEATDSEEEEDLE 468
Score = 35.8 bits (81), Expect = 0.50
Identities = 15/40 (37%), Positives = 26/40 (65%)
Query: 1930 SSRIHCGLQDSQKAGGAEDEQENEDDEEERDGEEEEEAEE 1969
+SR +D +++ E+E+E E++EE D EEEE+ E+
Sbjct: 430 ASRAETDDEDDEESDEEEEEEEEEEEEEATDSEEEEDLEQ 469
Score = 33.9 bits (76), Expect = 1.9
Identities = 14/28 (50%), Positives = 20/28 (71%)
Query: 1947 EDEQENEDDEEERDGEEEEEAEESNVED 1974
+DE + E DEEE + EEEEE E ++ E+
Sbjct: 436 DDEDDEESDEEEEEEEEEEEEEATDSEE 463
Score = 31.6 bits (70), Expect = 9.4
Identities = 15/34 (44%), Positives = 20/34 (58%)
Query: 1940 SQKAGGAEDEQENEDDEEERDGEEEEEAEESNVE 1973
SQ A + +++D+EE D EEEEE EE E
Sbjct: 424 SQGCPSASRAETDDEDDEESDEEEEEEEEEEEEE 457
>gi|215422388 death-domain associated protein isoform a [Homo sapiens]
Length = 740
Score = 37.7 bits (86), Expect = 0.13
Identities = 16/31 (51%), Positives = 25/31 (80%)
Query: 1947 EDEQENEDDEEERDGEEEEEAEESNVEDLLE 1977
ED++E++++EEE + EEEEEA +S E+ LE
Sbjct: 438 EDDEESDEEEEEEEEEEEEEATDSEEEEDLE 468
Score = 35.8 bits (81), Expect = 0.50
Identities = 15/40 (37%), Positives = 26/40 (65%)
Query: 1930 SSRIHCGLQDSQKAGGAEDEQENEDDEEERDGEEEEEAEE 1969
+SR +D +++ E+E+E E++EE D EEEE+ E+
Sbjct: 430 ASRAETDDEDDEESDEEEEEEEEEEEEEATDSEEEEDLEQ 469
Score = 33.9 bits (76), Expect = 1.9
Identities = 14/28 (50%), Positives = 20/28 (71%)
Query: 1947 EDEQENEDDEEERDGEEEEEAEESNVED 1974
+DE + E DEEE + EEEEE E ++ E+
Sbjct: 436 DDEDDEESDEEEEEEEEEEEEEATDSEE 463
Score = 31.6 bits (70), Expect = 9.4
Identities = 15/34 (44%), Positives = 20/34 (58%)
Query: 1940 SQKAGGAEDEQENEDDEEERDGEEEEEAEESNVE 1973
SQ A + +++D+EE D EEEEE EE E
Sbjct: 424 SQGCPSASRAETDDEDDEESDEEEEEEEEEEEEE 457
>gi|215422366 death-domain associated protein isoform b [Homo sapiens]
Length = 752
Score = 37.7 bits (86), Expect = 0.13
Identities = 16/31 (51%), Positives = 25/31 (80%)
Query: 1947 EDEQENEDDEEERDGEEEEEAEESNVEDLLE 1977
ED++E++++EEE + EEEEEA +S E+ LE
Sbjct: 450 EDDEESDEEEEEEEEEEEEEATDSEEEEDLE 480
Score = 35.8 bits (81), Expect = 0.50
Identities = 15/40 (37%), Positives = 26/40 (65%)
Query: 1930 SSRIHCGLQDSQKAGGAEDEQENEDDEEERDGEEEEEAEE 1969
+SR +D +++ E+E+E E++EE D EEEE+ E+
Sbjct: 442 ASRAETDDEDDEESDEEEEEEEEEEEEEATDSEEEEDLEQ 481
Score = 33.9 bits (76), Expect = 1.9
Identities = 14/28 (50%), Positives = 20/28 (71%)
Query: 1947 EDEQENEDDEEERDGEEEEEAEESNVED 1974
+DE + E DEEE + EEEEE E ++ E+
Sbjct: 448 DDEDDEESDEEEEEEEEEEEEEATDSEE 475
Score = 31.6 bits (70), Expect = 9.4
Identities = 15/34 (44%), Positives = 20/34 (58%)
Query: 1940 SQKAGGAEDEQENEDDEEERDGEEEEEAEESNVE 1973
SQ A + +++D+EE D EEEEE EE E
Sbjct: 436 SQGCPSASRAETDDEDDEESDEEEEEEEEEEEEE 469
>gi|195546902 suppressor of Ty 5 homolog isoform b [Homo sapiens]
Length = 1083
Score = 37.7 bits (86), Expect = 0.13
Identities = 16/37 (43%), Positives = 25/37 (67%)
Query: 1938 QDSQKAGGAEDEQENEDDEEERDGEEEEEAEESNVED 1974
++ + A G+E E+E ED+EEE + EE +E EE +D
Sbjct: 28 EERRSAAGSEKEEEPEDEEEEEEEEEYDEEEEEEDDD 64
>gi|195546900 suppressor of Ty 5 homolog isoform a [Homo sapiens]
Length = 1087
Score = 37.7 bits (86), Expect = 0.13
Identities = 16/37 (43%), Positives = 25/37 (67%)
Query: 1938 QDSQKAGGAEDEQENEDDEEERDGEEEEEAEESNVED 1974
++ + A G+E E+E ED+EEE + EE +E EE +D
Sbjct: 28 EERRSAAGSEKEEEPEDEEEEEEEEEYDEEEEEEDDD 64
>gi|161169023 suppressor of Ty 5 homolog isoform a [Homo sapiens]
Length = 1087
Score = 37.7 bits (86), Expect = 0.13
Identities = 16/37 (43%), Positives = 25/37 (67%)
Query: 1938 QDSQKAGGAEDEQENEDDEEERDGEEEEEAEESNVED 1974
++ + A G+E E+E ED+EEE + EE +E EE +D
Sbjct: 28 EERRSAAGSEKEEEPEDEEEEEEEEEYDEEEEEEDDD 64
>gi|20149524 suppressor of Ty 5 homolog isoform a [Homo sapiens]
Length = 1087
Score = 37.7 bits (86), Expect = 0.13
Identities = 16/37 (43%), Positives = 25/37 (67%)
Query: 1938 QDSQKAGGAEDEQENEDDEEERDGEEEEEAEESNVED 1974
++ + A G+E E+E ED+EEE + EE +E EE +D
Sbjct: 28 EERRSAAGSEKEEEPEDEEEEEEEEEYDEEEEEEDDD 64
>gi|4506411 Ran GTPase activating protein 1 [Homo sapiens]
Length = 587
Score = 37.7 bits (86), Expect = 0.13
Identities = 16/37 (43%), Positives = 24/37 (64%)
Query: 1938 QDSQKAGGAEDEQENEDDEEERDGEEEEEAEESNVED 1974
+D ++ E+E+E ++EEE D EEEEE EE E+
Sbjct: 361 EDEEEEEEGEEEEEEAEEEEEEDEEEEEEEEEEEEEE 397
Score = 37.0 bits (84), Expect = 0.22
Identities = 18/46 (39%), Positives = 28/46 (60%)
Query: 1928 KVSSRIHCGLQDSQKAGGAEDEQENEDDEEERDGEEEEEAEESNVE 1973
KV + + + ++ G E+E+E E++EEE + EEEEE EE E
Sbjct: 352 KVLASLSDDEDEEEEEEGEEEEEEAEEEEEEDEEEEEEEEEEEEEE 397
Score = 33.5 bits (75), Expect = 2.5
Identities = 16/25 (64%), Positives = 20/25 (80%), Gaps = 1/25 (4%)
Query: 1951 ENEDDEEERDG-EEEEEAEESNVED 1974
++ED+EEE +G EEEEEAEE ED
Sbjct: 359 DDEDEEEEEEGEEEEEEAEEEEEED 383
Score = 32.7 bits (73), Expect = 4.2
Identities = 15/36 (41%), Positives = 21/36 (58%)
Query: 1939 DSQKAGGAEDEQENEDDEEERDGEEEEEAEESNVED 1974
D + E E+E E+ EEE + +EEEE EE E+
Sbjct: 360 DEDEEEEEEGEEEEEEAEEEEEEDEEEEEEEEEEEE 395
Score = 32.7 bits (73), Expect = 4.2
Identities = 12/31 (38%), Positives = 23/31 (74%)
Query: 1939 DSQKAGGAEDEQENEDDEEERDGEEEEEAEE 1969
+ ++ E+E+E+E++EEE + EEEEE ++
Sbjct: 370 EEEEEEAEEEEEEDEEEEEEEEEEEEEEPQQ 400
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.320 0.135 0.406
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 87,642,550
Number of Sequences: 37866
Number of extensions: 4002701
Number of successful extensions: 23003
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 201
Number of HSP's successfully gapped in prelim test: 56
Number of HSP's that attempted gapping in prelim test: 17575
Number of HSP's gapped (non-prelim): 3360
length of query: 2286
length of database: 18,247,518
effective HSP length: 118
effective length of query: 2168
effective length of database: 13,779,330
effective search space: 29873587440
effective search space used: 29873587440
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 70 (31.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.