Guide to the Human Genome
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Name: POLA1 Sequence: fasta or formatted (1462aa) NCBI GI: 106507301
Description:

DNA-directed DNA polymerase alpha 1

Referenced in:

DNA Polymerases
Small RNAs in RNA Processing

Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine             5.9         86           2
 C cysteine            2.1         31           2
 D aspartate           7.1        104           3
 E glutamate           8.1        118           3
 F phenylalanine       4.0         58           2
 G glycine             5.3         77           2
 H histidine           1.7         25           2
 I isoleucine          5.6         82           2
 K lysine              9.4        137           4
 L leucine             9.2        134           4
 M methionine          2.3         34           1
 N asparagine          4.0         58           2
 P proline             5.1         74           3
 Q glutamine           4.7         68           2
 R arginine            3.9         57           2
 S serine              6.1         89           2
 T threonine           4.4         64           2
 V valine              6.9        101           2
 W tryptophan          0.9         13           1
 Y tyrosine            3.6         52           2
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   DNA-directed DNA polymerase alpha 1 
POLD1                 0.062   DNA-directed DNA polymerase delta 1 
REV3L                 0.040   DNA polymerase zeta 
POLE                  0.008   DNA-directed DNA polymerase epsilon 
MAK16                 0.008   MAK16 homolog 
MYST4                 0.005   MYST histone acetyltransferase (monocytic leukemia)...
SUPT6H                0.005   suppressor of Ty 6 homolog 
PELP1                 0.005   proline, glutamic acid and leucine rich protein 1 [...
NAP1L3                0.004   nucleosome assembly protein 1-like 3 
NRD1                  0.004   nardilysin isoform a 
NIP30                 0.004   hypothetical protein LOC80011 
CCDC88A               0.004   coiled-coil domain containing 88A isoform 2 
CCDC88A               0.004   coiled-coil domain containing 88A isoform 1 
MAP1B                 0.004   microtubule-associated protein 1B 
NSBP1                 0.004   nucleosomal binding protein 1 
CEBPZ                 0.004   CCAAT/enhancer binding protein zeta 
ATAD2                 0.004   ATPase family, AAA domain containing 2 
ASH1L                 0.004   absent, small, or homeotic 1-like 
EIF5B                 0.004   eukaryotic translation initiation factor 5B 
NEFM                  0.004   neurofilament, medium polypeptide 150kDa isoform 1 ...
NEFM                  0.004   neurofilament, medium polypeptide 150kDa isoform 2 ...
ELF2                  0.004   E74-like factor 2 (ets domain transcription factor) i...
CALD1                 0.004   caldesmon 1 isoform 5 
CALD1                 0.004   caldesmon 1 isoform 2 
CALD1                 0.004   caldesmon 1 isoform 1 
FLJ32682              0.004   hypothetical protein LOC220081 
SF3B2                 0.004   splicing factor 3B subunit 2 
CCDC82                0.003   coiled-coil domain containing 82 
PPM1G                 0.003   protein phosphatase 1G 
PPM1G                 0.003   protein phosphatase 1G 
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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