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Search of human proteins with 13569901
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|13569901 TSC22 domain family, member 4 [Homo sapiens]
(395 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|13569901 TSC22 domain family, member 4 [Homo sapiens] 800 0.0
gi|7662236 TSC22 domain family, member 2 [Homo sapiens] 117 2e-26
gi|171460948 TSC22 domain family, member 1 isoform 1 [Homo sapiens] 114 2e-25
gi|37622901 TSC22 domain family, member 3 isoform 2 [Homo sapiens] 108 6e-24
gi|5174729 TSC22 domain family, member 1 isoform 2 [Homo sapiens] 108 6e-24
gi|37622903 TSC22 domain family, member 3 isoform 1 [Homo sapiens] 104 1e-22
gi|62865625 TSC22 domain family, member 3 isoform 3 [Homo sapiens] 86 8e-17
gi|4502951 collagen type III alpha 1 preproprotein [Homo sapiens] 56 6e-08
gi|116284398 WAS/WASL interacting protein family, member 1 [Homo... 55 8e-08
gi|38373695 WAS/WASL interacting protein family, member 1 [Homo ... 55 8e-08
gi|163965366 nascent polypeptide-associated complex alpha subuni... 55 1e-07
gi|7657387 CCR4-NOT transcription complex, subunit 3 [Homo sapiens] 54 2e-07
gi|40805823 collagen, type XXII, alpha 1 [Homo sapiens] 54 3e-07
gi|4885407 hyperpolarization activated cyclic nucleotide-gated p... 53 5e-07
gi|110349772 alpha 1 type I collagen preproprotein [Homo sapiens] 52 9e-07
gi|162329583 cleavage and polyadenylation specific factor 6, 68 ... 52 1e-06
gi|110832843 TBP-associated factor 4 [Homo sapiens] 51 2e-06
gi|166706868 synaptopodin 2-like isoform a [Homo sapiens] 51 2e-06
gi|50301232 synaptopodin 2-like isoform b [Homo sapiens] 51 2e-06
gi|149158696 HLA-B associated transcript-3 isoform b [Homo sapiens] 51 2e-06
gi|18375632 HLA-B associated transcript-3 isoform b [Homo sapiens] 51 2e-06
gi|18375630 HLA-B associated transcript-3 isoform b [Homo sapiens] 51 2e-06
gi|149158692 HLA-B associated transcript-3 isoform a [Homo sapiens] 51 2e-06
gi|5032069 splicing factor 3b, subunit 4 [Homo sapiens] 51 2e-06
gi|18079216 CASK interacting protein 1 [Homo sapiens] 50 4e-06
gi|111118976 collagen, type II, alpha 1 isoform 1 precursor [Hom... 50 4e-06
gi|111118974 collagen, type II, alpha 1 isoform 2 precursor [Hom... 50 4e-06
gi|32964830 collagen, type VIII, alpha 2 [Homo sapiens] 49 6e-06
gi|116256464 hypothetical protein LOC343990 [Homo sapiens] 49 6e-06
gi|4502961 alpha 1 type VII collagen precursor [Homo sapiens] 49 8e-06
>gi|13569901 TSC22 domain family, member 4 [Homo sapiens]
Length = 395
Score = 800 bits (2065), Expect = 0.0
Identities = 395/395 (100%), Positives = 395/395 (100%)
Query: 1 MSGGKKKSSFQITSVTTDYEGPGSPGASDPPTPQPPTGPPPRLPNGEPSPDPGGKGTPRN 60
MSGGKKKSSFQITSVTTDYEGPGSPGASDPPTPQPPTGPPPRLPNGEPSPDPGGKGTPRN
Sbjct: 1 MSGGKKKSSFQITSVTTDYEGPGSPGASDPPTPQPPTGPPPRLPNGEPSPDPGGKGTPRN 60
Query: 61 GSPPPGAPSSRFRVVKLPHGLGEPYRRGRWTCVDVYERDLEPHSFGGLLEGIRGASGGAG 120
GSPPPGAPSSRFRVVKLPHGLGEPYRRGRWTCVDVYERDLEPHSFGGLLEGIRGASGGAG
Sbjct: 61 GSPPPGAPSSRFRVVKLPHGLGEPYRRGRWTCVDVYERDLEPHSFGGLLEGIRGASGGAG 120
Query: 121 GRSLDSRLELASLGLGAPTPPSGLSQGPTSWLRPPPTSPGPQARSFTGGLGQLVVPSKAK 180
GRSLDSRLELASLGLGAPTPPSGLSQGPTSWLRPPPTSPGPQARSFTGGLGQLVVPSKAK
Sbjct: 121 GRSLDSRLELASLGLGAPTPPSGLSQGPTSWLRPPPTSPGPQARSFTGGLGQLVVPSKAK 180
Query: 181 AEKPPLSASSPQQRPPEPETGESAGTSRAATPLPSLRVEAEAGGSGARTPPLSRRKAVDM 240
AEKPPLSASSPQQRPPEPETGESAGTSRAATPLPSLRVEAEAGGSGARTPPLSRRKAVDM
Sbjct: 181 AEKPPLSASSPQQRPPEPETGESAGTSRAATPLPSLRVEAEAGGSGARTPPLSRRKAVDM 240
Query: 241 RLRMELGAPEEMGQVPPLDSRPSSPALYFTHDASLVHKSPDPFGAVAAQKFSLAHSMLAI 300
RLRMELGAPEEMGQVPPLDSRPSSPALYFTHDASLVHKSPDPFGAVAAQKFSLAHSMLAI
Sbjct: 241 RLRMELGAPEEMGQVPPLDSRPSSPALYFTHDASLVHKSPDPFGAVAAQKFSLAHSMLAI 300
Query: 301 SGHLDSDDDSGSGSLVGIDNKIEQAMDLVKSHLMFAVREEVEVLKEQIRELAERNAALEQ 360
SGHLDSDDDSGSGSLVGIDNKIEQAMDLVKSHLMFAVREEVEVLKEQIRELAERNAALEQ
Sbjct: 301 SGHLDSDDDSGSGSLVGIDNKIEQAMDLVKSHLMFAVREEVEVLKEQIRELAERNAALEQ 360
Query: 361 ENGLLRALASPEQLAQLPSSGVPRLGPPAPNGPSV 395
ENGLLRALASPEQLAQLPSSGVPRLGPPAPNGPSV
Sbjct: 361 ENGLLRALASPEQLAQLPSSGVPRLGPPAPNGPSV 395
>gi|7662236 TSC22 domain family, member 2 [Homo sapiens]
Length = 780
Score = 117 bits (292), Expect = 2e-26
Identities = 109/362 (30%), Positives = 154/362 (42%), Gaps = 64/362 (17%)
Query: 25 PGASDPPTPQPPTGPPPRLPNG--EPSPDPGGKGTPRNGSPPPGAPSSRFRVVKLPHGLG 82
P P PTG PP G +P P G G P++ PP S V P G
Sbjct: 443 PAQGGQVAPCQPTGVPPATVGGVVQPCLGPAGAGQPQSVPPPQMGGSGPLSAV--PGG-- 498
Query: 83 EPYRRGRWTCVDVYERDLEPHSFGGLLEGIRGASGGAGGRSLDSRLELASLGLGAPTPPS 142
PH+ ++ G+ S+ S +++ + P P+
Sbjct: 499 -------------------PHA---VVPGVPNVPAAVPAPSVPS---VSTTSVTMPNVPA 533
Query: 143 GLSQGPTSWLRPPPTSPGPQARSFTGGLGQLVVPSKAKAEKP-PLSASSPQQRPPEPETG 201
L+Q + +P ++ S +G + P A P S S Q +P G
Sbjct: 534 PLAQSQ----QLSSHTPVSRSSSIIQHVGLPLAPGTHSAPTSLPQSDLSQFQTQTQPLVG 589
Query: 202 ESAGTSRAATPLPSLRVEAEAGGSGARTPPLSRRKAVDMRLR-MELGAPEEMGQVPPLDS 260
+ T R + PLP + A PP++ A ++L M A P+D
Sbjct: 590 QVDDTRRKSEPLPQPPLSLIAENKPVVKPPVADSLANPLQLTPMNSLATSVFSIAIPVDG 649
Query: 261 ---RPSSPALYFTHDASLVHKSPDPFGAVAAQKFSLAHSMLAISGHLDSDDDSGSGSLVG 317
R S A Y + + +S + D + G +V
Sbjct: 650 DEDRNPSTAFYQAFHLNTLKESKSLW------------------------DSASGGGVVA 685
Query: 318 IDNKIEQAMDLVKSHLMFAVREEVEVLKEQIRELAERNAALEQENGLLRALASPEQLAQL 377
IDNKIEQAMDLVKSHLM+AVREEVEVLKEQI+EL ERN+ LE+EN LL++L+S +QL+QL
Sbjct: 686 IDNKIEQAMDLVKSHLMYAVREEVEVLKEQIKELVERNSLLERENALLKSLSSNDQLSQL 745
Query: 378 PS 379
P+
Sbjct: 746 PT 747
Score = 83.6 bits (205), Expect = 3e-16
Identities = 94/327 (28%), Positives = 130/327 (39%), Gaps = 41/327 (12%)
Query: 27 ASDPPTPQPPTGPPPRLPNGEPSPDPGGKGTPRNGSPPPGAPSSRFRVVKLPHGLGEPYR 86
A+ P P P GP +L P S PP SSRFRV+KL HG GEPYR
Sbjct: 125 ATSAPAPGAPGGP--QLAGSSAGPVTAAP------SQPPTTCSSRFRVIKLDHGSGEPYR 176
Query: 87 RGRWTCVDVYERDLEPHSFGGLLEGIRGAS---------GGAGGRSLDSRLELASLGLGA 137
RGRWTC++ YERD + + IR +S G G + +AS+ GA
Sbjct: 177 RGRWTCMEYYERDSDSSVLTRSGDCIRHSSTFDQTAERDSGLGATGGSVVVVVASM-QGA 235
Query: 138 PTPPSGLSQGPTSWLRPPP----TSPGP-QARSFTGG--------LGQLVVPSKAKAEKP 184
P SG T+ + PP + P P Q +SF+ G +G V S A
Sbjct: 236 HGPESGTDSSLTAVSQLPPSEKMSQPTPAQPQSFSVGQPQPPPPPVGGAVAQSSAPLPPF 295
Query: 185 PLSASSPQQRPPEPETGESAGTSRAATPLPSLRVEAEAGGSGARTPPLSRRKAVDMRLRM 244
P +A+ PQ + + G LP V P A +
Sbjct: 296 PGAATGPQPMMAAAQPSQPQGAGPGGQTLPPTNVTLAQPAMSLPPQPGPAVGAPAAQQPQ 355
Query: 245 ELGAPEEMGQVPP---LDSRPSSPALYF-THDASLVHKSP-DPFGAVAAQKFSLAHSMLA 299
+ P+ Q+PP L +PS + Y H A L SP P AA + A ++
Sbjct: 356 QFAYPQP--QIPPGHLLPVQPSGQSEYLQQHVAGLQPPSPAQPSSTGAAASPATAATLPV 413
Query: 300 ISGHLDSDDDSGSGSLVGIDNKIEQAM 326
+G + S L+G ++ +AM
Sbjct: 414 GTG---QNASSVGAQLMGASSQPSEAM 437
>gi|171460948 TSC22 domain family, member 1 isoform 1 [Homo sapiens]
Length = 1073
Score = 114 bits (284), Expect = 2e-25
Identities = 101/282 (35%), Positives = 135/282 (47%), Gaps = 21/282 (7%)
Query: 123 SLDSRLELASLG--LGAPTPPSGL---SQGPTSWLRPPPTSPGPQARSFTGGLGQLVVPS 177
SL +L +AS L P P G+ +QG S + P S P A S + V S
Sbjct: 783 SLPQQLVIASQSSLLTVPPQPQGVEPVAQGIVSQ-QLPAVSSLPSASSIS-------VTS 834
Query: 178 KAKAEKPPLSASSPQQRPPEPETGESAGTSRA----ATPLPSLRVEAEAGGSGARTPPLS 233
+ + P S+P P ++ T + P L + A+ PLS
Sbjct: 835 QVSSTGPSGMPSAPTNLVPPQNIAQTPATQNGNLVQSVSQPPL-IATNTNLPLAQQIPLS 893
Query: 234 RRKAVDMRLRMELGAPEEMGQVPPLDSRPSSPALYFTHDASLVHKSPDPFGAVAAQKFSL 293
+ L +G+ E + S P + S ++AA
Sbjct: 894 STQFSAQSLAQAIGSQIEDARRAAEPSLVGLPQTISGDSGGMSAVSDGSSSSLAASASLF 953
Query: 294 AHSMLAISGHL-DSDDDSGSG-SLVGIDNKIEQAMDLVKSHLMFAVREEVEVLKEQIREL 351
+L ++ L D +D+S SG S+V IDNKIEQAMDLVKSHLM+AVREEVEVLKEQI+EL
Sbjct: 954 PLKVLPLTTPLVDGEDESSSGASVVAIDNKIEQAMDLVKSHLMYAVREEVEVLKEQIKEL 1013
Query: 352 AERNAALEQENGLLRALASPEQLAQLPSSGVPRLGPPAPNGP 393
E+N+ LEQEN LL+ LASPEQLAQ + + PPA P
Sbjct: 1014 IEKNSQLEQENNLLKTLASPEQLAQFQAQ-LQTGSPPATTQP 1054
Score = 43.9 bits (102), Expect = 3e-04
Identities = 64/254 (25%), Positives = 94/254 (37%), Gaps = 46/254 (18%)
Query: 56 GTPRNGSPPPGAPSSRFRVVKLPHGLGEPYRRGRWTCVDVYERDLEPHSFGGLL------ 109
G+ + P +SRFRVVKL EP+++GRWTC + YE++ + G+L
Sbjct: 391 GSVSSQQQQPTVNTSRFRVVKLDSS-SEPFKKGRWTCTEFYEKENAVPATEGVLINKVVE 449
Query: 110 -------------EGIRGASGGAGGRSLDSRLELASLG-LGAPTPPSGLSQGPTSWLRPP 155
E G+S + +L E G +GAPT Q +
Sbjct: 450 TVKQNPIEVTSERESTSGSSVSSSVSTLSHYTESVGSGEMGAPTVVVQQQQQQQQQQQQQ 509
Query: 156 PT------------SPGPQ---ARSFTGGLGQLVVPSKAKAEKPPLSASSPQQRPPEP-E 199
P S GPQ A S + Q + S+ + + LS Q P P +
Sbjct: 510 PALQGVTLQQMDFGSTGPQSIPAVSIPQSISQSQI-SQVQLQSQELSYQQKQGLQPVPLQ 568
Query: 200 TGESAGTSRAATPLPSLRVEAEAGG----SGARTPPLSRRKAVDMRLRMELGAPE----E 251
SA T +P+ + V + G S P L +A GAP +
Sbjct: 569 ATMSAATGIQPSPVNVVGVTSALGQQPSISSLAQPQLPYSQAAPPVQTPLPGAPPPQQLQ 628
Query: 252 MGQVPPLDSRPSSP 265
GQ P+ S +P
Sbjct: 629 YGQQQPMVSTQMAP 642
>gi|37622901 TSC22 domain family, member 3 isoform 2 [Homo sapiens]
Length = 134
Score = 108 bits (271), Expect = 6e-24
Identities = 61/123 (49%), Positives = 80/123 (65%), Gaps = 5/123 (4%)
Query: 276 VHKSPDPFGAVAAQKFSLAHSMLAISGHLDS---DDDSGSGSLVGIDNKIEQAMDLVKSH 332
++++P FS++ + G + S D+ + S+V IDNKIEQAMDLVK+H
Sbjct: 5 MYQTPMEVAVYQLHNFSISFFSSLLGGDVVSVKLDNSASGASVVAIDNKIEQAMDLVKNH 64
Query: 333 LMFAVREEVEVLKEQIRELAERNAALEQENGLLRALASPEQLAQLPSSGVPRLGPPAPNG 392
LM+AVREEVE+LKEQIREL E+N+ LE+EN LL+ LASPEQL + S P PAP
Sbjct: 65 LMYAVREEVEILKEQIRELVEKNSQLERENTLLKTLASPEQLEKFQSCLSPE--EPAPES 122
Query: 393 PSV 395
P V
Sbjct: 123 PQV 125
>gi|5174729 TSC22 domain family, member 1 isoform 2 [Homo sapiens]
Length = 144
Score = 108 bits (271), Expect = 6e-24
Identities = 58/87 (66%), Positives = 67/87 (77%), Gaps = 1/87 (1%)
Query: 307 DDDSGSGSLVGIDNKIEQAMDLVKSHLMFAVREEVEVLKEQIRELAERNAALEQENGLLR 366
D+ S S+V IDNKIEQAMDLVKSHLM+AVREEVEVLKEQI+EL E+N+ LEQEN LL+
Sbjct: 40 DNSSSGASVVAIDNKIEQAMDLVKSHLMYAVREEVEVLKEQIKELIEKNSQLEQENNLLK 99
Query: 367 ALASPEQLAQLPSSGVPRLGPPAPNGP 393
LASPEQLAQ + + PPA P
Sbjct: 100 TLASPEQLAQFQAQ-LQTGSPPATTQP 125
>gi|37622903 TSC22 domain family, member 3 isoform 1 [Homo sapiens]
Length = 200
Score = 104 bits (260), Expect = 1e-22
Identities = 58/87 (66%), Positives = 67/87 (77%), Gaps = 3/87 (3%)
Query: 310 SGSG-SLVGIDNKIEQAMDLVKSHLMFAVREEVEVLKEQIRELAERNAALEQENGLLRAL 368
S SG S+V IDNKIEQAMDLVK+HLM+AVREEVE+LKEQIREL E+N+ LE+EN LL+ L
Sbjct: 107 SASGASVVAIDNKIEQAMDLVKNHLMYAVREEVEILKEQIRELVEKNSQLERENTLLKTL 166
Query: 369 ASPEQLAQLPSSGVPRLGPPAPNGPSV 395
ASPEQL + S P PAP P V
Sbjct: 167 ASPEQLEKFQSCLSPE--EPAPESPQV 191
>gi|62865625 TSC22 domain family, member 3 isoform 3 [Homo sapiens]
Length = 77
Score = 85.5 bits (210), Expect = 8e-17
Identities = 45/70 (64%), Positives = 53/70 (75%), Gaps = 2/70 (2%)
Query: 326 MDLVKSHLMFAVREEVEVLKEQIRELAERNAALEQENGLLRALASPEQLAQLPSSGVPRL 385
MDLVK+HLM+AVREEVE+LKEQIREL E+N+ LE+EN LL+ LASPEQL + S P
Sbjct: 1 MDLVKNHLMYAVREEVEILKEQIRELVEKNSQLERENTLLKTLASPEQLEKFQSCLSPE- 59
Query: 386 GPPAPNGPSV 395
PAP P V
Sbjct: 60 -EPAPESPQV 68
>gi|4502951 collagen type III alpha 1 preproprotein [Homo sapiens]
Length = 1466
Score = 55.8 bits (133), Expect = 6e-08
Identities = 78/280 (27%), Positives = 95/280 (33%), Gaps = 59/280 (21%)
Query: 21 GPGSPGASDPPT---------PQPPTGP-PPRLPNGEPSPD-----PGGKGTP-RNGSPP 64
GPG PG PP P PTGP + G P P PG G P NG P
Sbjct: 598 GPGGPGPQGPPGKNGETGPQGPPGPTGPGGDKGDTGPPGPQGLQGLPGTGGPPGENGKPG 657
Query: 65 PGAPSSRFRVVKLPHGLGE---PYRRGRWTCVDVYERDLEPHSFGGLLEGIRGASGGAGG 121
P P G G+ P RG P G G+RG +G G
Sbjct: 658 EPGPKGDAGAPGAPGGKGDAGAPGERG-------------PPGLAG-APGLRGGAGPPGP 703
Query: 122 RSLDSRLELASLGLGAPTPPSGLSQGPTSWLRPPP------TSPGPQA-RSFTGGLGQLV 174
G GA PP T L+ P SPGP+ + GG G
Sbjct: 704 EG----------GKGAAGPPGPPGAAGTPGLQGMPGERGGLGSPGPKGDKGEPGGPGADG 753
Query: 175 VPSKAKAEKP--PLSASSPQQRPPEPETGESAGTSRAATPLPSLRVEAEAGGSGARTPPL 232
VP K P P+ P +P + G + G A P S E G G P
Sbjct: 754 VPGKDGPRGPTGPIGPPGPAGQPGDKGEGGAPGLPGIAGPRGSPGERGETGPPGPAGFPG 813
Query: 233 SRRKAVDMRLRMELGAPEEMGQ-------VPPLDSRPSSP 265
+ + + + E GAP E G+ PP S P+ P
Sbjct: 814 APGQNGEPGGKGERGAPGEKGEGGPPGVAGPPGGSGPAGP 853
Score = 48.9 bits (115), Expect = 8e-06
Identities = 62/216 (28%), Positives = 73/216 (33%), Gaps = 26/216 (12%)
Query: 22 PGSPGASDPPTPQPPTGPPPRLPNGEPSPDPGGKGTPRNGSPP-PGAPSSRFRVVKLPHG 80
PG PGA P P GP + P+ PG KG G+P PG R
Sbjct: 746 PGGPGADGVPGKDGPRGPTGPIGPPGPAGQPGDKG--EGGAPGLPGIAGPR--------- 794
Query: 81 LGEPYRRGRWTCVDVYERDLEPHSFGGLLEGIRGASGGAGGRSLDSRL-ELASLGLGAPT 139
G P RG P F G G G GG G R E G+ P
Sbjct: 795 -GSPGERGE-------TGPPGPAGFPGA-PGQNGEPGGKGERGAPGEKGEGGPPGVAGPP 845
Query: 140 PPSGLS--QGPTSWLRPPPTSPGPQARSFTGGLGQLVVPSKAKAEKPPLSASSP-QQRPP 196
SG + GP + GP A F G G P PP + SP + PP
Sbjct: 846 GGSGPAGPPGPQGVKGERGSPGGPGAAGFPGARGLPGPPGSNGNPGPPGPSGSPGKDGPP 905
Query: 197 EPETGESA-GTSRAATPLPSLRVEAEAGGSGARTPP 231
P A G+ + P E G GA+ PP
Sbjct: 906 GPAGNTGAPGSPGVSGPKGDAGQPGEKGSPGAQGPP 941
Score = 42.7 bits (99), Expect = 6e-04
Identities = 67/239 (28%), Positives = 83/239 (34%), Gaps = 59/239 (24%)
Query: 22 PGSPGASDPPTPQPPTGPPPRLPNGEPSPDPGGKG-TPRNGSPPPGAPSSRFRVVKLPHG 80
PG PG P P GP +G+P P PG +G + R G P P P + V+ P
Sbjct: 530 PGGPGMRG--MPGSPGGPGS---DGKPGP-PGSQGESGRPGPPGPSGPRGQPGVMGFPGP 583
Query: 81 LGEPYRRGRWTCVDVYERDLEPHSFGGLLEGIRGASGGAGGRSLDSRL-ELASLGLGAPT 139
G G+ G RG GG G + + E G PT
Sbjct: 584 KGNDGAPGK--------------------NGERGGPGGPGPQGPPGKNGETGPQGPPGPT 623
Query: 140 PPSGLS-----------QGPTSWLRPP-----PTSPGPQ----ARSFTGGLGQLVVPSKA 179
P G QG PP P PGP+ A GG G P +
Sbjct: 624 GPGGDKGDTGPPGPQGLQGLPGTGGPPGENGKPGEPGPKGDAGAPGAPGGKGDAGAPGE- 682
Query: 180 KAEKPPLSASSPQQR----PPEPETGESAG---TSRAATPLPSLR-VEAEAGGSGARTP 230
PP A +P R PP PE G+ A A P L+ + E GG G+ P
Sbjct: 683 --RGPPGLAGAPGLRGGAGPPGPEGGKGAAGPPGPPGAAGTPGLQGMPGERGGLGSPGP 739
Score = 42.7 bits (99), Expect = 6e-04
Identities = 52/184 (28%), Positives = 67/184 (36%), Gaps = 57/184 (30%)
Query: 22 PGSPGASDPPTPQPPTGPPPRLPNGEPSPDPGGKGTPRNGSPP-----PGAPSSRFRVVK 76
PG PGA+ P + GPP NG P P PG G+P PP GAP S V
Sbjct: 866 PGGPGAAGFPGARGLPGPPG--SNGNPGP-PGPSGSPGKDGPPGPAGNTGAPGS--PGVS 920
Query: 77 LPHG-LGEPYRRGRWTCVDVYERDLEPHSFGGLLEGIRGASGGAGGRSLDSRLELASLGL 135
P G G+P +G G +G G G LG+
Sbjct: 921 GPKGDAGQPGEKGS--------------------PGAQGPPGAPG-----------PLGI 949
Query: 136 GAPTPPSGLSQGPTSWLRPPPTSPGPQARSFTGGLGQLVVPSKAKAEKPPLSASSPQQRP 195
T GL+ P + P SPGPQ K ++ KP + S ++ P
Sbjct: 950 AGITGARGLAGPP--GMPGPRGSPGPQG-------------VKGESGKPGANGLSGERGP 994
Query: 196 PEPE 199
P P+
Sbjct: 995 PGPQ 998
Score = 37.7 bits (86), Expect = 0.018
Identities = 69/254 (27%), Positives = 85/254 (33%), Gaps = 62/254 (24%)
Query: 30 PPTPQPPTGPP----PRLPNGEPSPDPGGKGTPRNGSP----PPGAPSSRFRVVKLPHGL 81
P P PT PP P+ P G+P P PG G RNG P PG+P S P G+
Sbjct: 89 PQPPTAPTRPPNGQGPQGPKGDPGP-PGIPG--RNGDPGIPGQPGSPGS-----PGPPGI 140
Query: 82 GEPYRRGRWTCVDVYERDLEPHSFGGLLEGIRGASGGAGGRSLDSRLELASLGLGAPTPP 141
E G Y D G + G+ G G A G P PP
Sbjct: 141 CESCPTGPQNYSPQY--DSYDVKSGVAVGGLAGYPGPA----------------GPPGPP 182
Query: 142 SGLSQGPTSWLRPPPTSPGPQARSFTGGLGQLVVPSKAKAEKPPLSASSPQQRPPEPETG 201
PP TS P + G G P +A PP + P + G
Sbjct: 183 G-----------PPGTSGHPGSPGSPGYQGPPGEPGQAGPSGPPGPPGAIGPSGPAGKDG 231
Query: 202 ESAGTSR---AATPLPSLRVEAEAGGSGARTPPLSRRKAVDMR-----------LRMELG 247
ES R P P ++ AG G P + + D R L+ E G
Sbjct: 232 ESGRPGRPGERGLPGPP-GIKGPAGIPG--FPGMKGHRGFDGRNGEKGETGAPGLKGENG 288
Query: 248 APEEMGQVPPLDSR 261
P E G P+ R
Sbjct: 289 LPGENGAPGPMGPR 302
Score = 36.6 bits (83), Expect = 0.041
Identities = 65/228 (28%), Positives = 75/228 (32%), Gaps = 40/228 (17%)
Query: 22 PGSPGASDPPT------PQPPTGPPPRLPNGEPSPDPGGKGTP----RNGSP-PPGAPSS 70
PGSPG PP P P GPP + P+ G G P G P PPG
Sbjct: 194 PGSPGYQGPPGEPGQAGPSGPPGPPGAIGPSGPAGKDGESGRPGRPGERGLPGPPG---- 249
Query: 71 RFRVVKLPHGL-GEPYRRGRWTCVDVYERDLEPHSFGGL-----LEGIRGASGGAGGRSL 124
+K P G+ G P +G D + GL L G GA G G R
Sbjct: 250 ----IKGPAGIPGFPGMKGH-RGFDGRNGEKGETGAPGLKGENGLPGENGAPGPMGPRGA 304
Query: 125 DSRLELASLGLGAPTPPSGLSQGPTSWLRPPPTSPGPQARSFTGGLGQLVVPSKAKAEKP 184
E GL G S +P P P P F G G AK E
Sbjct: 305 PG--ERGRPGLPGAAGARGNDGARGSDGQPGPPGP-PGTAGFPGSPG-------AKGEVG 354
Query: 185 PLSASSPQQRPPEPETGESA--GTSRAATPLPSLRVEAEAGGSGARTP 230
P A SP + GE G + A P + GG G P
Sbjct: 355 P--AGSPGSNGAPGQRGEPGPQGHAGAQGPPGPPGINGSPGGKGEMGP 400
Score = 34.7 bits (78), Expect = 0.15
Identities = 56/210 (26%), Positives = 72/210 (34%), Gaps = 27/210 (12%)
Query: 21 GP-GSPGASDPPTPQPPTGPPPRLPNGEPSPDPGGKGTPRNGSPPPGAPSSRFRVVKLPH 79
GP G GA PP P G P P+ PG G G+ P P+ L
Sbjct: 372 GPQGHAGAQGPPGPPGINGSPGGKGEMGPAGIPGAPGL--MGARGPPGPAGANGAPGLRG 429
Query: 80 GLGEPYRRGRWTCVDVYERDLEPHSFGGL--LEGIRGASG-----GAGGRSLDSRL---- 128
G GEP + G + + P G + G+ GA G G+ G + L
Sbjct: 430 GAGEPGKNGA-------KGEPGPRGERGEAGIPGVPGAKGEDGKDGSPGEPGANGLPGAA 482
Query: 129 -ELASLGLGAPTPPSGL--SQGPTSWLRPPPTSPGPQARSFTGGLGQLVVPSKAKAEKPP 185
E + G P P+G+ +GP R P GP R G G+ VP P
Sbjct: 483 GERGAPGFRGPAGPNGIPGEKGPAG-ERGAPGPAGP--RGAAGEPGRDGVPGGPGMRGMP 539
Query: 186 LSASSPQQRPPEPETGESAGTSRAATPLPS 215
S P G + R P PS
Sbjct: 540 GSPGGPGSDGKPGPPGSQGESGRPGPPGPS 569
Score = 33.9 bits (76), Expect = 0.26
Identities = 47/173 (27%), Positives = 58/173 (33%), Gaps = 31/173 (17%)
Query: 22 PGSPGASDPPTPQPPTGPPPRLPNGEPSPDPGGKGTP----RNGSPPPGAPSSRFRVVKL 77
PG+PGA P P P GP + + S G G P G+P P P
Sbjct: 1040 PGAPGAPGHPGPPGPVGPAGKSGDRGESGPAGPAGAPGPAGSRGAPGPQGPRG------- 1092
Query: 78 PHGLGEPYRRGRWTCVDVYERDLEPHSFGGLLEGIRGASGGAGGRSLDSRLELASLGLGA 137
GE RG ++ H G G+ G AG + + S G
Sbjct: 1093 --DKGETGERG--------AAGIKGHRGFPGNPGAPGSPGPAGQQG-----AIGSPGPAG 1137
Query: 138 PTPPSGLSQGP----TSWLRPPPTSPGPQA-RSFTGGLGQLVVPSKAKAEKPP 185
P P G S P TS P PGP+ R G G P + PP
Sbjct: 1138 PRGPVGPSGPPGKDGTSGHPGPIGPPGPRGNRGERGSEGSPGHPGQPGPPGPP 1190
Score = 32.3 bits (72), Expect = 0.76
Identities = 65/230 (28%), Positives = 78/230 (33%), Gaps = 38/230 (16%)
Query: 23 GSPGASDPPTPQPPTGPP--PRLPNGEPSPDPGGKGTPRNGSPPPGAPSSRFRVVKLPHG 80
G PG + PP P P G P P P G+ S PPG P + P G
Sbjct: 171 GYPGPAGPPGPPGPPGTSGHPGSPGSPGYQGPPGEPGQAGPSGPPGPPGAIG-----PSG 225
Query: 81 L----GEPYRRGRWTCVDVYERDLE-PHSFGGLLEGIRGASGGAGGRSLDSRL----ELA 131
GE R GR ER L P G GI G G G R D R E
Sbjct: 226 PAGKDGESGRPGR-----PGERGLPGPPGIKG-PAGIPGFPGMKGHRGFDGRNGEKGETG 279
Query: 132 SLGLGAPT--PPSGLSQGPTSWLRPPPTSPG-------PQARSFTGGLGQLVVPSKAKAE 182
+ GL P + GP P +PG P A G G +
Sbjct: 280 APGLKGENGLPGENGAPGPMG----PRGAPGERGRPGLPGAAGARGNDGARGSDGQPGPP 335
Query: 183 KPPLSASSPQQRPPEPETGESAGTSRAATPLPSLRVE-AEAGGSGARTPP 231
PP +A P + E G + S + P R E G +GA+ PP
Sbjct: 336 GPPGTAGFPGSPGAKGEVGPAG--SPGSNGAPGQRGEPGPQGHAGAQGPP 383
Score = 29.3 bits (64), Expect = 6.5
Identities = 27/79 (34%), Positives = 29/79 (36%), Gaps = 33/79 (41%)
Query: 22 PGSPGASDPP--TPQPPTGPP-------------------------PRLPNGEPSPDPGG 54
PGSPG+ PP PTGP P P G P P PG
Sbjct: 129 PGSPGSPGPPGICESCPTGPQNYSPQYDSYDVKSGVAVGGLAGYPGPAGPPGPPGP-PGT 187
Query: 55 KGTPRN-GSP----PPGAP 68
G P + GSP PPG P
Sbjct: 188 SGHPGSPGSPGYQGPPGEP 206
>gi|116284398 WAS/WASL interacting protein family, member 1 [Homo
sapiens]
Length = 503
Score = 55.5 bits (132), Expect = 8e-08
Identities = 65/252 (25%), Positives = 84/252 (33%), Gaps = 29/252 (11%)
Query: 19 YEGPGSPGASDPPTPQPPTGPPPRLPNGEPSPDPGGKGTPRNGSPPPGAPSSRFRVVKLP 78
+ P PG P+P +GPP N P P P P S PP PS+ + P
Sbjct: 141 FSPPSGPGRFPVPSPGHRSGPPEPQRNRMPPPRPDVGSKP--DSIPPPVPSTPRPIQSSP 198
Query: 79 HGLGEPYRRGRWTCVDVYERDLEPHSFGGLLEGIRGASGGAGGRSLDSRLELASLGLGAP 138
H G P G R P G RG + G G + P
Sbjct: 199 HNRGSPPVPGG-------PRQPSPGPTPPPFPGNRGTALGGGSIRQSPLSSSSPFSNRPP 251
Query: 139 TPPSGLSQGPTSWLRPPPTSPGPQARSFTGGLGQLVVPSKAKAEKPPLSA----SSPQQR 194
PP+ P+ L P P P + + V P + KPP+ + S+ Q
Sbjct: 252 LPPT-----PSRALDDKPPPPPPPVGNRPSIHREAVPPPPPQNNKPPVPSTPRPSASSQA 306
Query: 195 PPEPETGESAGTSRAATPLPSLRVEAEAGGSGARTPPLSRRKAVDMRLRMELGAPEEMGQ 254
PP P G PLP + TP L +R L +P G
Sbjct: 307 PPPPPPPSRPG----PPPLP------PSSSGNDETPRLPQRNLSLSSSTPPLPSPGRSGP 356
Query: 255 VPPLDS-RPSSP 265
+PP S RP P
Sbjct: 357 LPPPPSERPPPP 368
Score = 43.5 bits (101), Expect = 3e-04
Identities = 58/205 (28%), Positives = 68/205 (33%), Gaps = 47/205 (22%)
Query: 30 PPTPQPPTGPPPRLPN-GEPSPDPGGKGTPRNGSPPPGAPSSRFRVVKLPHGLGEPYRRG 88
PP P PP G P + P P P P +P P A S P G P
Sbjct: 264 PPPPPPPVGNRPSIHREAVPPPPPQNNKPPVPSTPRPSASSQAPPPPPPPSRPGPP---- 319
Query: 89 RWTCVDVYERDLEPHSFGGLLEGIRGASGGAGGRSLDSRLELASLGLGAPTPPSGLSQGP 148
L P S G RL +L L + TPP S G
Sbjct: 320 ----------PLPPSS---------------SGNDETPRLPQRNLSLSSSTPPLP-SPGR 353
Query: 149 TSWLRPPPTS-PGPQARSFTGGLGQLVVP---------SKAKAEKPPLSA----SSPQQ- 193
+ L PPP+ P P R G G L P S+A P L + SP+
Sbjct: 354 SGPLPPPPSERPPPPVRDPPGRSGPLPPPPPVSRNGSTSRALPATPQLPSRSGVDSPRSG 413
Query: 194 -RPPEPETGESAGTSRAATPLPSLR 217
RPP P SAG P S+R
Sbjct: 414 PRPPLPPDRPSAGAPPPPPPSTSIR 438
Score = 32.7 bits (73), Expect = 0.59
Identities = 20/62 (32%), Positives = 25/62 (40%), Gaps = 1/62 (1%)
Query: 9 SFQITSVTTDYEGPGSPGASDPPTPQPPTGPPPRLPNGEPSPDPGGKGTPRNGSPPPGAP 68
+ ++S T PG G PP P PP R P G P P RNGS P
Sbjct: 338 NLSLSSSTPPLPSPGRSGPLPPP-PSERPPPPVRDPPGRSGPLPPPPPVSRNGSTSRALP 396
Query: 69 SS 70
++
Sbjct: 397 AT 398
Score = 32.7 bits (73), Expect = 0.59
Identities = 21/48 (43%), Positives = 22/48 (45%), Gaps = 10/48 (20%)
Query: 24 SPGASDPPTPQPPTGPPPRLPNGEPSPDPGGKGTPRNGSPPPGAPSSR 71
SPG S P P P PPP P DP G R+G PP P SR
Sbjct: 350 SPGRSGPLPPPPSERPPP------PVRDPPG----RSGPLPPPPPVSR 387
Score = 32.0 bits (71), Expect = 1.00
Identities = 19/51 (37%), Positives = 23/51 (45%), Gaps = 1/51 (1%)
Query: 23 GSPGASDPPTPQPPTGPPPRLPNGEPSPDPGGKGTPRNGSPPPGAPSSRFR 73
GS + P TPQ P+ P P P P P G+PPP PS+ R
Sbjct: 389 GSTSRALPATPQLPSRSGVDSPRSGPRP-PLPPDRPSAGAPPPPPPSTSIR 438
>gi|38373695 WAS/WASL interacting protein family, member 1 [Homo
sapiens]
Length = 503
Score = 55.5 bits (132), Expect = 8e-08
Identities = 65/252 (25%), Positives = 84/252 (33%), Gaps = 29/252 (11%)
Query: 19 YEGPGSPGASDPPTPQPPTGPPPRLPNGEPSPDPGGKGTPRNGSPPPGAPSSRFRVVKLP 78
+ P PG P+P +GPP N P P P P S PP PS+ + P
Sbjct: 141 FSPPSGPGRFPVPSPGHRSGPPEPQRNRMPPPRPDVGSKP--DSIPPPVPSTPRPIQSSP 198
Query: 79 HGLGEPYRRGRWTCVDVYERDLEPHSFGGLLEGIRGASGGAGGRSLDSRLELASLGLGAP 138
H G P G R P G RG + G G + P
Sbjct: 199 HNRGSPPVPGG-------PRQPSPGPTPPPFPGNRGTALGGGSIRQSPLSSSSPFSNRPP 251
Query: 139 TPPSGLSQGPTSWLRPPPTSPGPQARSFTGGLGQLVVPSKAKAEKPPLSA----SSPQQR 194
PP+ P+ L P P P + + V P + KPP+ + S+ Q
Sbjct: 252 LPPT-----PSRALDDKPPPPPPPVGNRPSIHREAVPPPPPQNNKPPVPSTPRPSASSQA 306
Query: 195 PPEPETGESAGTSRAATPLPSLRVEAEAGGSGARTPPLSRRKAVDMRLRMELGAPEEMGQ 254
PP P G PLP + TP L +R L +P G
Sbjct: 307 PPPPPPPSRPG----PPPLP------PSSSGNDETPRLPQRNLSLSSSTPPLPSPGRSGP 356
Query: 255 VPPLDS-RPSSP 265
+PP S RP P
Sbjct: 357 LPPPPSERPPPP 368
Score = 43.5 bits (101), Expect = 3e-04
Identities = 58/205 (28%), Positives = 68/205 (33%), Gaps = 47/205 (22%)
Query: 30 PPTPQPPTGPPPRLPN-GEPSPDPGGKGTPRNGSPPPGAPSSRFRVVKLPHGLGEPYRRG 88
PP P PP G P + P P P P +P P A S P G P
Sbjct: 264 PPPPPPPVGNRPSIHREAVPPPPPQNNKPPVPSTPRPSASSQAPPPPPPPSRPGPP---- 319
Query: 89 RWTCVDVYERDLEPHSFGGLLEGIRGASGGAGGRSLDSRLELASLGLGAPTPPSGLSQGP 148
L P S G RL +L L + TPP S G
Sbjct: 320 ----------PLPPSS---------------SGNDETPRLPQRNLSLSSSTPPLP-SPGR 353
Query: 149 TSWLRPPPTS-PGPQARSFTGGLGQLVVP---------SKAKAEKPPLSA----SSPQQ- 193
+ L PPP+ P P R G G L P S+A P L + SP+
Sbjct: 354 SGPLPPPPSERPPPPVRDPPGRSGPLPPPPPVSRNGSTSRALPATPQLPSRSGVDSPRSG 413
Query: 194 -RPPEPETGESAGTSRAATPLPSLR 217
RPP P SAG P S+R
Sbjct: 414 PRPPLPPDRPSAGAPPPPPPSTSIR 438
Score = 32.7 bits (73), Expect = 0.59
Identities = 20/62 (32%), Positives = 25/62 (40%), Gaps = 1/62 (1%)
Query: 9 SFQITSVTTDYEGPGSPGASDPPTPQPPTGPPPRLPNGEPSPDPGGKGTPRNGSPPPGAP 68
+ ++S T PG G PP P PP R P G P P RNGS P
Sbjct: 338 NLSLSSSTPPLPSPGRSGPLPPP-PSERPPPPVRDPPGRSGPLPPPPPVSRNGSTSRALP 396
Query: 69 SS 70
++
Sbjct: 397 AT 398
Score = 32.7 bits (73), Expect = 0.59
Identities = 21/48 (43%), Positives = 22/48 (45%), Gaps = 10/48 (20%)
Query: 24 SPGASDPPTPQPPTGPPPRLPNGEPSPDPGGKGTPRNGSPPPGAPSSR 71
SPG S P P P PPP P DP G R+G PP P SR
Sbjct: 350 SPGRSGPLPPPPSERPPP------PVRDPPG----RSGPLPPPPPVSR 387
Score = 32.0 bits (71), Expect = 1.00
Identities = 19/51 (37%), Positives = 23/51 (45%), Gaps = 1/51 (1%)
Query: 23 GSPGASDPPTPQPPTGPPPRLPNGEPSPDPGGKGTPRNGSPPPGAPSSRFR 73
GS + P TPQ P+ P P P P P G+PPP PS+ R
Sbjct: 389 GSTSRALPATPQLPSRSGVDSPRSGPRP-PLPPDRPSAGAPPPPPPSTSIR 438
>gi|163965366 nascent polypeptide-associated complex alpha subunit
isoform a [Homo sapiens]
Length = 2078
Score = 54.7 bits (130), Expect = 1e-07
Identities = 70/265 (26%), Positives = 90/265 (33%), Gaps = 35/265 (13%)
Query: 16 TTDYEGPGSPGASDPPTPQ-----PPTGPPPRLPNGEPSPDPGGKGTPRNGSPPPGAPSS 70
T +G P A+ PP+P+ PP P P P GG TP PP GAP++
Sbjct: 1096 TPSPKGAPMPPAATPPSPKGGLATPPHKGAPTTPAATPPSPKGGLATP----PPKGAPTT 1151
Query: 71 RFRVVKLPH-GLGEPYRRGRWTCVDVYERDLEPHSFGGL-LEGIRGASGGAGGRSLDSRL 128
P GL P +G T P GGL +GA +
Sbjct: 1152 PAATPPSPKGGLATPPPKGAPTT----PAATPPSPKGGLATPSPKGAPTTPAATPPSPKG 1207
Query: 129 ELASLG-LGAPTPPSGLSQGPTSWLRPP-----PTSPGPQARSFTGGLGQLVVPSKAKAE 182
LA+ GAPT P+ P L P PT+P S GG A
Sbjct: 1208 GLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGG----------PAT 1257
Query: 183 KPPLSASSPQQRPPEPETGESAGTSRAATPLPSLRVEAEAGGSGARTPPLSRRKAVDMRL 242
PP A +P P G A P P++ G A +PP K
Sbjct: 1258 PPPKGAPTPPAATPPSLKGGLATPPHKGAPNPAVVTPPSPKGGPATSPP----KGAPTPP 1313
Query: 243 RMELGAPEEMGQVPPLDSRPSSPAL 267
+P+ PP P+ PA+
Sbjct: 1314 AATPPSPKGSPGTPPPKGAPTPPAV 1338
Score = 47.8 bits (112), Expect = 2e-05
Identities = 70/278 (25%), Positives = 88/278 (31%), Gaps = 26/278 (9%)
Query: 16 TTDYEGPGSP--GASDPP---TPQPPTGPPPRLPNGEPSPDPGGKGTPRNGSPPPGAPSS 70
TT P SP G + PP P P PP G +P P KG P + P +P
Sbjct: 1127 TTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPPP--KGAPTTPAATPPSPKG 1184
Query: 71 RFRVVKLPHGLGEPYRRGRWTCVDVYERDLEPHSFGGL-LEGIRGASGGAGGRSLDSRLE 129
GL P +G T P GGL +GA +
Sbjct: 1185 ---------GLATPSPKGAPTT----PAATPPSPKGGLATPSPKGAPTTPAATPPSPKGG 1231
Query: 130 LASLG-LGAPTPPSGLSQGPTSW--LRPPPTSPGPQARSFTGGLGQLVVPSKAKAEKPPL 186
LA+ GAPT P+ P PP +P P A + G L P A P +
Sbjct: 1232 LATPSPKGAPTTPAATPPSPKGGPATPPPKGAPTPPAATPPSLKGGLATPPHKGAPNPAV 1291
Query: 187 SASSPQQRPPEPETGESAGTSRAATPLPSLRVEAEAGGSGARTPPLSRRKAVDMRLRMEL 246
+ P + A T AATP GA TPP + +
Sbjct: 1292 VTPPSPKGGPATSPPKGAPTPPAATPPSPKGSPGTPPPKGAPTPPAVTPPSPKGTPTLPA 1351
Query: 247 GAPEEMG--QVPPLDSRPSSPALYFTHDASLVHKSPDP 282
P G P P+ PA +H P P
Sbjct: 1352 TTPSSKGGPTTPSSKEGPTPPAATPSHKGGPAMTPPSP 1389
Score = 47.4 bits (111), Expect = 2e-05
Identities = 64/256 (25%), Positives = 84/256 (32%), Gaps = 42/256 (16%)
Query: 21 GPGSPGASDPPTPQPPTGPPPRLPNGEPSPDPGGKGTPRNGSPP-----PGAPSSRFRVV 75
GP +P PTP P PP G +P P G TP +PP P PS +
Sbjct: 953 GPATPSPKWAPTP--PAATPPSPKGGPATPSPKGAPTPPAATPPSPKGGPATPSP--KGA 1008
Query: 76 KLPHGLGEPYRRGRWTCVDVYERDLEPHSFGGLLEGIRGASGGAGGRSLDSRLELASLGL 135
P + P +G + P + A S L
Sbjct: 1009 PTPPAVTPPSPKGSPAATPFPKGASTPPA--------------ATPPSPKGSPAATPLPK 1054
Query: 136 GAPTPPSGLSQGP-----TSWLRPPPTSPGPQARSFTGGLGQLVVPSKAKAEKPPLSASS 190
GAPT P+ P T L+ PT P S GG PS A PP +
Sbjct: 1055 GAPTTPAATLPSPKGGPATPSLKGAPTPPAATPPSPKGG---PATPSPKGAPMPPAAT-- 1109
Query: 191 PQQRPPEPETGESAGTSRAATPLPSLRVEAEAGGSGARTPPLSRRKAVDMRLRMELGAPE 250
PP P+ G + + A P+ + G G TPP K +P+
Sbjct: 1110 ----PPSPKGGLATPPHKGAPTTPAATPPSPKG--GLATPP---PKGAPTTPAATPPSPK 1160
Query: 251 EMGQVPPLDSRPSSPA 266
PP P++PA
Sbjct: 1161 GGLATPPPKGAPTTPA 1176
Score = 46.6 bits (109), Expect = 4e-05
Identities = 69/281 (24%), Positives = 86/281 (30%), Gaps = 77/281 (27%)
Query: 14 SVTTDYEGPGSPGASDPP-TPQPPTGPPPRLPNGEPSPDPGGKGTPRNGSPPPGAPSSRF 72
+V T G P S P P PP PP P G P GTP PP GAP+
Sbjct: 1290 AVVTPPSPKGGPATSPPKGAPTPPAATPPS-PKGSP-------GTP----PPKGAPT--- 1334
Query: 73 RVVKLPHGLGEPYRRGRWTCVDVYERDLEPHSFGGLLEGIRGASGGAGGRSLDSRLELAS 132
P + P +G T P S GG
Sbjct: 1335 -----PPAVTPPSPKGTPTLPAT-----TPSSKGG------------------------- 1359
Query: 133 LGLGAPTPPSGLSQGPTSWLRPPPTSPGPQARSFTGGLGQLVVPSKAKAEKPPLSASSPQ 192
PT PS +GPT P GP + G + K P + SP+
Sbjct: 1360 -----PTTPSS-KEGPTPPAATPSHKGGPAMTPPSPKRGPAIPSPKGDPTSPAVIPLSPK 1413
Query: 193 QRPPEPETGESAGTSR-------AATPLPSLRVEAEAGGSGARTPPLSRRKAVDMRLRME 245
+ P P T E A T A TP+ + A + G P S+
Sbjct: 1414 KAPATPVTREGAATPSKGDLTPPAVTPVSLKKAPATSAPKGGPATPSSK----------- 1462
Query: 246 LGAPEEMGQVPPLDSRPSSPALYFTHDA-SLVHKSPDPFGA 285
G P PP P +P T + +P P GA
Sbjct: 1463 -GDPTLPAVTPPSPKEPPAPKQVATSSSPKKAPATPAPMGA 1502
Score = 41.2 bits (95), Expect = 0.002
Identities = 61/260 (23%), Positives = 92/260 (35%), Gaps = 23/260 (8%)
Query: 22 PGSPGASDPPTPQPPTGPPPRLPNGEPSPDPGGKGTPRNGS------PPPGAPSSRFRVV 75
PG+P PTP T P P+ P+ P KG P S PP PS +
Sbjct: 1324 PGTPPPKGAPTPPAVTPPSPKGTPTLPATTPSSKGGPTTPSSKEGPTPPAATPSHKGGPA 1383
Query: 76 KLP----HGLGEPYRRGRWTCVDVYERDLEPHSFGGLLEGIRGASGGAGGRSLDSRLELA 131
P G P +G T V L P GA+ + G +
Sbjct: 1384 MTPPSPKRGPAIPSPKGDPTSPAVI--PLSPKKAPATPVTREGAATPSKGDLTPPAVTPV 1441
Query: 132 SLGLG-APTPPSGLSQGPTSW---LRPPPTSPGPQARSFTGGLGQLVVPSKAKAEKPPLS 187
SL A + P G P+S P T P P+ + P KA A P+
Sbjct: 1442 SLKKAPATSAPKGGPATPSSKGDPTLPAVTPPSPKEPPAPKQVATSSSPKKAPATPAPMG 1501
Query: 188 ASS-PQQRPPEPETGESAGTSRAATPLPSLRVEAEAGGSGARTPPLSRRKAVDMRLRMEL 246
A + P P P+ + +SR P+ + ++ +TP K + M +
Sbjct: 1502 APTLPAVIPSSPKEVPATPSSRRDPIAPTATLLSK------KTPATLAPKEALIPPAMTV 1555
Query: 247 GAPEEMGQVPPLDSRPSSPA 266
+P++ +P P++P+
Sbjct: 1556 PSPKKTPAIPTPKEAPATPS 1575
Score = 38.9 bits (89), Expect = 0.008
Identities = 61/274 (22%), Positives = 82/274 (29%), Gaps = 68/274 (24%)
Query: 20 EGPGSPGASDPP--------------TPQPPTGPPPRLPNGEPSPDPGGKGTPRNGSPPP 65
EGP +P P TP P P P G P+P +P+ G P
Sbjct: 898 EGPATPAPKQAPALSMTSSSPKKARATPAPKGIPASPSPKGAPTPPAATPPSPKGG---P 954
Query: 66 GAPSSRFRVVKLPHGLGEPYRRGRWTCVDVYERDLEPHSFGGLLEGIRGASGGAGGRSLD 125
PS ++ P P +G P G GG +
Sbjct: 955 ATPSPKW--APTPPAATPPSPKG---------GPATPSPKGAPTPPAATPPSPKGGPATP 1003
Query: 126 SRLELASLGLGAPTPPSGLSQGPTSWLRPPPTSPGPQARSFTGGLGQLVVPSKAKAEKPP 185
S GAPTPP+ + PP P A F G S A PP
Sbjct: 1004 S-------PKGAPTPPA---------VTPPSPKGSPAATPFPKG------ASTPPAATPP 1041
Query: 186 LSASSPQQRP-------------PEPETGESAGTSRAATPLPSLRVEAEAGGSGARTPPL 232
SP P P P+ G + + + A P+ + GG +P
Sbjct: 1042 SPKGSPAATPLPKGAPTTPAATLPSPKGGPATPSLKGAPTPPAATPPSPKGGPATPSP-- 1099
Query: 233 SRRKAVDMRLRMELGAPEEMGQVPPLDSRPSSPA 266
K M +P+ PP P++PA
Sbjct: 1100 ---KGAPMPPAATPPSPKGGLATPPHKGAPTTPA 1130
Score = 37.4 bits (85), Expect = 0.024
Identities = 63/256 (24%), Positives = 89/256 (34%), Gaps = 51/256 (19%)
Query: 24 SPGASDPPTPQPPTGPPPRLPNGEPSPDPGGKGTPRNGSPPPGAPSSRFRVVKLPHGLGE 83
SP + PTP T P P P+P KGTP + PP PSS
Sbjct: 1607 SPSPKEAPTPPAVTPPSPEKGPATPAP----KGTP---TSPPVTPSSL---------KDS 1650
Query: 84 PYRRGRWTCVDVYERDLEPHSFGGLL-EGIRGASGGAGGRSLDSRLELASLGLGAPTPPS 142
P TC G + + +G G +L L +A P +
Sbjct: 1651 PTSPASVTC-----------KMGATVPQASKGLPAKKGPTALKEVL-VAPAPESTPIITA 1698
Query: 143 GLSQGP---TSWLRPPPTSPGPQARSFTGGLGQLVVPSK-AKAEKPPLSASSPQQRPPEP 198
+GP S PP P P A++ + G V P+ +K + + P
Sbjct: 1699 PTRKGPQTKKSSATSPPICPDPSAKNGSKGPLSTVAPAPLLPVQKDSSKTAKGKDASHSP 1758
Query: 199 ETGESAGTSRAATPLPSLRVE------AEAGGSGARTPPLSRRKAVDMRLRMELGAPEEM 252
+ + S+A+TPL + E A S A +PP+S AP +
Sbjct: 1759 KGPLAPPESKASTPLTAAAFEKVLPKPESASVSAAPSPPVSLPL-----------APSPV 1807
Query: 253 GQVPPLDS-RPSSPAL 267
+PP PSSP L
Sbjct: 1808 PTLPPKQQFLPSSPGL 1823
Score = 30.8 bits (68), Expect = 2.2
Identities = 46/188 (24%), Positives = 62/188 (32%), Gaps = 36/188 (19%)
Query: 136 GAPTPPSGLSQGPTSWLRPPPTSPGPQARSFTGGLGQLVVPSKAKAEKPPLSASSPQQR- 194
GAPTP + P PP +P P + P+ +A +++SSP++
Sbjct: 863 GAPTPSAVTPLSPKGVTLPPKETPTPSVVNLPFPKEGPATPAPKQAPALSMTSSSPKKAR 922
Query: 195 ------------------------PPEPETGES------AGTSRAATPLPSLRVEAEAGG 224
PP P+ G + A T AATP A
Sbjct: 923 ATPAPKGIPASPSPKGAPTPPAATPPSPKGGPATPSPKWAPTPPAATPPSPKGGPATPSP 982
Query: 225 SGARTPPLSRRKAV--DMRLRMELGAPEEMGQVPPLDSRPSSPALYFTHDASL--VHKSP 280
GA TPP + + GAP PP + S A F AS P
Sbjct: 983 KGAPTPPAATPPSPKGGPATPSPKGAPTPPAVTPP-SPKGSPAATPFPKGASTPPAATPP 1041
Query: 281 DPFGAVAA 288
P G+ AA
Sbjct: 1042 SPKGSPAA 1049
>gi|7657387 CCR4-NOT transcription complex, subunit 3 [Homo sapiens]
Length = 753
Score = 54.3 bits (129), Expect = 2e-07
Identities = 68/261 (26%), Positives = 88/261 (33%), Gaps = 28/261 (10%)
Query: 20 EGPGSPGASDPPTPQPPTGP--PPRLPNGEPSPDPGGKGTP-RNGSPPPGAPSSRFRVVK 76
+ P G+ + Q P P PP P+G P TP NG P P AP S
Sbjct: 298 QSPAKNGSKPVHSNQHPQSPAVPPTYPSGPPPAASALSTTPGNNGVPAPAAPPSALGPKA 357
Query: 77 LP-----HGLGEPYRRGRWTCVDVYERDLEPHSFGGLLEGIRGASGGAGGRSLDSRLELA 131
P G PY + +P G G G GG S S +
Sbjct: 358 SPAPSHNSGTPAPYAQAVAPPAPSGPSTTQPRPPSVQPSGGGGGGSGGGGSSSSSN---S 414
Query: 132 SLGLGAPTPPSGLSQGPTSWLRPPPTSPGPQARSFTGG---LGQLVVPSKAKAEKPPLSA 188
S G GA G G TS+ SP A S +GG Q + P PP ++
Sbjct: 415 SAGGGA-----GKQNGATSYSSVVADSPAEVALSSSGGNNASSQALGPPSGPHNPPPSTS 469
Query: 189 SSPQQRPPEPETGESAGTSRAATPLPSLRVEAEAGGSGARTPPLSRRKAVDMRLR----- 243
P P G + G+ + PSL V + TP S KA L
Sbjct: 470 KEPSAAAPTGAGGVAPGSGNNSGG-PSLLVPLPVNPPSSPTPSFSDAKAAGALLNGPPQF 528
Query: 244 ---MELGAPEEMGQVPPLDSR 261
E+ APE + + + R
Sbjct: 529 STAPEIKAPEPLSSLKSMAER 549
>gi|40805823 collagen, type XXII, alpha 1 [Homo sapiens]
Length = 1626
Score = 53.5 bits (127), Expect = 3e-07
Identities = 84/267 (31%), Positives = 98/267 (36%), Gaps = 44/267 (16%)
Query: 22 PGSPGASDPPTPQPPTGPPPR-LPNGEPSPDPGGKGTP--RNGSPPPGAPSSRFRVVKLP 78
PG G P P PTGPP + PNG P P PG KG P R PG P R + +
Sbjct: 734 PGEIGFPGKPGPPGPTGPPGKDGPNGPPGP-PGTKGEPGERGEDGLPGKPGLRGEIGE-- 790
Query: 79 HGL-GEPYRRGRWTCVDVYERDLEPHSFGGLLEGIRGASGGAGGRSLDSRLELASL---- 133
GL G P +G E L P + G G+RG G G + L L L
Sbjct: 791 QGLAGRPGEKG--------EAGL-PGAPG--FPGVRGEKGDQGEK---GELGLPGLKGDR 836
Query: 134 ---GLGAPTPPSGLSQGPTSWLRPPPTSPGPQARSFTGGLGQLVVPSKAKAEKPP--LSA 188
G P P GL G TS P P PG Q G G +P + + P L
Sbjct: 837 GEKGEAGPAGPPGL-PGTTSLFTPHPRMPGEQGPK--GEKGDPGLPGEPGLQGRPGELGP 893
Query: 189 SSPQQRPPEPETGESAGTSRAATPLPSLRVEAEAGGSGARTPPLS------RRKAVDMRL 242
P PP + E A + A P G G PP S R
Sbjct: 894 QGP-TGPPGAKGQEGAHGAPGAAGNPG--APGHVGAPGPSGPPGSVGAPGLRGTPGKDGE 950
Query: 243 RMELGAPEEMGQVPPLDSR--PSSPAL 267
R E GA E G P+ R P +P L
Sbjct: 951 RGEKGAAGEEGSPGPVGPRGDPGAPGL 977
Score = 46.2 bits (108), Expect = 5e-05
Identities = 81/283 (28%), Positives = 100/283 (35%), Gaps = 61/283 (21%)
Query: 23 GSPGASDPPTPQPPTGPPPRLPNGEP-SP-DPGGKGTP-------RNGSP---------- 63
G G + P PQ P GPP + NG P SP +PG GTP NGSP
Sbjct: 1309 GDTGPTGPQGPQGPRGPPGK--NGSPGSPGEPGPSGTPGQKGSKGENGSPGLPGFLGPRG 1366
Query: 64 PPGAPSSRFRVVK--LPHGLGEPYRRGRWTCVDVYERDLEPHSFGGLLEGIRGASGGAGG 121
PPG P + K +P GEP +G ER +P GI+G G GG
Sbjct: 1367 PPGEPGEKGVPGKEGVPGKPGEPGFKG--------ERG-DP--------GIKGDKGPPGG 1409
Query: 122 RSLDSRLEL----ASLGLGAPTPPSGLSQGPTSWLRPP--PTSPGPQARS-FTGGLGQLV 174
+ + GL P G GP PP P PG + S L +L+
Sbjct: 1410 KGQPGDPGIPGHKGHTGLMGPQGLPG-ENGPVGPPGPPGQPGFPGLRGESPSMETLRRLI 1468
Query: 175 VPSKAK----------AEKPPLSASSPQQRPPEPETGESAGTSRAATPLPSLRVEAEAGG 224
K A+ PP S Q RP P G A P+ + G
Sbjct: 1469 QEELGKQLETRLAYLLAQMPPAYMKSSQGRPGPPGPPGKDGLPGRAGPMGEPGRPGQGGL 1528
Query: 225 SGARTP--PLSRRKAVDMRLRMELGAPEEMGQVPPLDSRPSSP 265
G P P R A +G EMG P + +P P
Sbjct: 1529 EGPSGPIGPKGERGAKGDPGAPGVGLRGEMGP-PGIPGQPGEP 1570
Score = 43.1 bits (100), Expect = 4e-04
Identities = 76/257 (29%), Positives = 94/257 (36%), Gaps = 47/257 (18%)
Query: 23 GSPGASDPPTPQPPTGPPPRLPNGEPSPDPGGKGTPRNGSP-PPGAPSSRFRVVKLPHGL 81
GSPG PP PQ P+G P G P + G +G R+G P PPG P
Sbjct: 1219 GSPGKEGPPGPQGPSGLP-----GIPG-EEGKEG--RDGKPGPPGEPGK----------A 1260
Query: 82 GEPYRRGRWTCVDVYERDLEPHSFGGLL--EGIRGASGGAGGRSLDSRLELASLGLGAPT 139
GEP G E P F G G G G +G L + L G T
Sbjct: 1261 GEPGLPGP-------EGARGPPGFKGHTGDSGAPGPRGESGAMGLPGQEGLP--GKDGDT 1311
Query: 140 PPSGLSQGPTSWLRPP-----PTSPGPQARSFTGGLGQLVVPSKAKAEKPPLSASSPQQR 194
P+G QGP PP P SPG S T G SK + P L +
Sbjct: 1312 GPTG-PQGPQGPRGPPGKNGSPGSPGEPGPSGTPG----QKGSKGENGSPGLPGFLGPRG 1366
Query: 195 PPEPETGESAGTSRAATP----LPSLRVE-AEAGGSGARTPPLSRRKAVDMRLRMELGAP 249
PP E GE + P P + E + G G + PP + + D + G
Sbjct: 1367 PP-GEPGEKGVPGKEGVPGKPGEPGFKGERGDPGIKGDKGPPGGKGQPGDPGIPGHKGHT 1425
Query: 250 EEMG-QVPPLDSRPSSP 265
MG Q P ++ P P
Sbjct: 1426 GLMGPQGLPGENGPVGP 1442
Score = 35.0 bits (79), Expect = 0.12
Identities = 68/239 (28%), Positives = 79/239 (33%), Gaps = 46/239 (19%)
Query: 18 DYEGPGSPGASDPPTPQPPTG-------PPPRLPNGEPS----PDPG-----GKGTPRNG 61
D PGS G P PQ P G P R P G+P PG K +
Sbjct: 1058 DKGSPGSRGLPGFPGPQGPAGRDGAPGNPGERGPPGKPGLSSLLSPGDINLLAKDVCNDC 1117
Query: 62 SP-PPGAPSSRFRVVKLPHGL-GEPYRRGRWTCVDVYERDLEPHSFGGLLEGIRGASGGA 119
P PPG P K G+ G+P R G + + + P G GI G G
Sbjct: 1118 PPGPPGLPG--LPGFKGDKGVPGKPGREG----TEGKKGEAGPPGLPG-PPGIAGPQGSQ 1170
Query: 120 GGRSLDSRLELASLG-LGAPTPPSGLSQGPTSWLRPPPTSPGPQ-ARSFTGGLGQLVVPS 177
G R D E+ G G P P + PP +PGP A G G +
Sbjct: 1171 GERGADG--EVGQKGDQGHPGVPGFMG---------PPGNPGPPGADGIAGAAGPPGIQG 1219
Query: 178 KAKAEKPPLSASSPQQRPPEPETGESAGTSRAATPLP-----SLRVEAEAGGSGARTPP 231
E PP P P P GE R P P G GAR PP
Sbjct: 1220 SPGKEGPP-GPQGPSGLPGIP--GEEGKEGRDGKPGPPGEPGKAGEPGLPGPEGARGPP 1275
Score = 34.7 bits (78), Expect = 0.15
Identities = 83/323 (25%), Positives = 99/323 (30%), Gaps = 97/323 (30%)
Query: 22 PGSPGASDPPTPQPPTGPPPRL----------------PNGEPSPD--PGGKG-TPRNGS 62
PG G P P GPP R+ GE D PG G T + G
Sbjct: 562 PGEVGMRGPQGPPGLPGPPGRVGAPGLQGERGEKGTRGEKGERGLDGFPGKPGDTGQQGR 621
Query: 63 P-------------------PPGAPSSRFRVVKLPHGLGEPYRRGRWTC---------VD 94
P PPG P S + L G P RG +
Sbjct: 622 PGPSGVAGPQGEKGDVGPAGPPGVPGSVVQQEGLKGEQGAPGPRGHQGAPGPPGARGPIG 681
Query: 95 VYERDLEPHSFGGLLEGIRGASGGAGGRSLDSRLELASLGLGAPTPPSGLSQGPTSWLRP 154
RD P L+G+RG G G + L L QGP
Sbjct: 682 PEGRDGPPG-----LQGLRGKKGDMGPPGIPGLLGL---------------QGPPG---- 717
Query: 155 PPTSPGPQARSFTGGL-GQLVVPSKAKAEKP--PLSASSPQQRPPEPET-GESAGTSRAA 210
PP PGP + GL G++ P K P P P P P T GE
Sbjct: 718 PPGVPGPPGPGGSPGLPGEIGFPGKPGPPGPTGPPGKDGPNGPPGPPGTKGEPGERGEDG 777
Query: 211 TP-LPSLRVE-------------AEAGGSGARTPPLSRRKAVDMRLRMELGAP------E 250
P P LR E EAG GA P R + D + ELG P
Sbjct: 778 LPGKPGLRGEIGEQGLAGRPGEKGEAGLPGAPGFPGVRGEKGDQGEKGELGLPGLKGDRG 837
Query: 251 EMGQVPPL--DSRPSSPALYFTH 271
E G+ P P + +L+ H
Sbjct: 838 EKGEAGPAGPPGLPGTTSLFTPH 860
Score = 33.9 bits (76), Expect = 0.26
Identities = 59/238 (24%), Positives = 82/238 (34%), Gaps = 32/238 (13%)
Query: 28 SDPPTPQPPTGPPPRLPNGEP--------SPDPGGKGTPRNGSPPPGAPSSRFRVVKLPH 79
++PP P PP PP P E P G+ + P G P + + +
Sbjct: 449 TEPPPPPPPQRPP--TPGSEQIGFLKTINCSCPAGEKGEMGVAGPMGLPGPKGDIGAI-G 505
Query: 80 GLGEPYRRGRWTCVDVYERDLEPHSFGGLLEGIRGASG--GAGGRSLDSRLELASLGLGA 137
+G P +G + D+ FG +G +G+ G G GR + LG
Sbjct: 506 PVGAPGPKGE-------KGDVGIGPFGQGEKGEKGSLGLPGPPGRDGSKGMRGEPGELGE 558
Query: 138 PTPPSGLS-QGPTSWLRPPPTSPGPQARSFTGGLGQLVVPSKAKAEKPPLSASSPQQRPP 196
P P + +GP + PP PGP R GL + EK +P
Sbjct: 559 PGLPGEVGMRGP----QGPPGLPGPPGRVGAPGLQGERGEKGTRGEKGERGLDGFPGKPG 614
Query: 197 EPETGESAGTSRAATPLPSLRVEAEAGGSGARTPPLSRRKAVDMR-LRMELGAPEEMG 253
+ G S A P + E G G PP V L+ E GAP G
Sbjct: 615 DTGQQGRPGPSGVAGP------QGEKGDVGPAGPPGVPGSVVQQEGLKGEQGAPGPRG 666
Score = 32.3 bits (72), Expect = 0.76
Identities = 49/168 (29%), Positives = 60/168 (35%), Gaps = 41/168 (24%)
Query: 23 GSPGA----SDPPTPQPPTGPPPRLPNGEPSPDPGGKGTPRNGSPPPGAPSSRFRVVKLP 78
GSPG DP P P GPP + +GE PG +G+P LP
Sbjct: 961 GSPGPVGPRGDPGAPGLP-GPPGKGKDGE----PGLRGSP-----------------GLP 998
Query: 79 HGLGEPYRRGRWTCVDVYERDLEPHSFGG-LLEGIRGASGGAGGRSLDSRLELASLGLGA 137
LG G+ R E + GG ++G RGA G G + G
Sbjct: 999 GPLGTKAACGK-------VRGSENCALGGQCVKGDRGAPGIPGSPGSRGDPGIGVAGPPG 1051
Query: 138 PTPPSGLSQGPTSWLRPPPTSPGPQARSFTGGLGQLVVPSKAKAEKPP 185
P+ P G P S R P PGPQ G G+ P PP
Sbjct: 1052 PSGPPGDKGSPGS--RGLPGFPGPQ-----GPAGRDGAPGNPGERGPP 1092
>gi|4885407 hyperpolarization activated cyclic nucleotide-gated
potassium channel 4 [Homo sapiens]
Length = 1203
Score = 52.8 bits (125), Expect = 5e-07
Identities = 69/225 (30%), Positives = 84/225 (37%), Gaps = 40/225 (17%)
Query: 22 PGSPGASDPPTPQPPTGPPPRLPNGEPSPDPGGKGTPRNGSPPPGAPSSRFRVVKLPHGL 81
P PGA P QP PP GG G P + PPP PSSR P L
Sbjct: 928 PLQPGARSPQAAQPSPAPPGA---------RGGLGLPEHFLPPP--PSSR-SPSSSPGQL 975
Query: 82 GEP-------YRRGRWTCVDVYERDLEPHSFGGLLEGIRGASGGAGGRSLDSRLELASLG 134
G+P G + + R EP S + GASGGA R L+ G
Sbjct: 976 GQPPGELSLGLATGPLSTPETPPRQPEPPSL------VAGASGGASPVGFTPRGGLSPPG 1029
Query: 135 LGAPTPPSGLSQGPT-------SWLRPPPTSPGPQARSFTGGLGQLVVPSKAKAEKPPLS 187
+P PP P S L PP +SP P G L P + + +S
Sbjct: 1030 -HSPGPPRTFPSAPPRASGSHGSLLLPPASSPPPPQVPQRRGTPPL-TPGRLTQDLKLIS 1087
Query: 188 ASSPQQRPPEPET-----GESAGTSRAATPLPSLRVEAEAGGSGA 227
AS P +T S+G S AA PL R +GGSG+
Sbjct: 1088 ASQPALPQDGAQTLRRASPHSSGESMAAFPL-FPRAGGGSGGSGS 1131
Score = 40.8 bits (94), Expect = 0.002
Identities = 54/189 (28%), Positives = 68/189 (35%), Gaps = 50/189 (26%)
Query: 36 PTGPPPRLPNGEPSPDPGGKGTPRNGSPPPGAPSSRFRVVKLPHGLGEPYRRGRWTCVDV 95
P G P LP+ SP PG G+P +P G ++ G G ++
Sbjct: 868 PAGLSPLLPSSSSSPPPGACGSPSAPTPSAGVAATTIA------GFGHFHK--------- 912
Query: 96 YERDLEPHSFGGLLEGIRGASGGAGGRSLDSRLELASLGLGAPTP--------PSGLSQG 147
+ GG L S DS L L L GA +P P G G
Sbjct: 913 --------ALGGSLS------------SSDSPL-LTPLQPGARSPQAAQPSPAPPGARGG 951
Query: 148 ---PTSWLRPPPTSPGPQARSFTGGLGQLVVPSKAKAEKPPLSASSPQQRPPEPETGESA 204
P +L PPP+S P S G LGQ PLS R PEP + A
Sbjct: 952 LGLPEHFLPPPPSSRSPS--SSPGQLGQPPGELSLGLATGPLSTPETPPRQPEPPS-LVA 1008
Query: 205 GTSRAATPL 213
G S A+P+
Sbjct: 1009 GASGGASPV 1017
Score = 37.4 bits (85), Expect = 0.024
Identities = 58/217 (26%), Positives = 72/217 (33%), Gaps = 59/217 (27%)
Query: 14 SVTTDYEGPGSPGASDPPTPQPPTGPPPRLPNGEPSPDPGGKGT-------PRNGSPPPG 66
S+ G SP P P G P P PS P G+ P + PPP
Sbjct: 1005 SLVAGASGGASPVGFTPRGGLSPPGHSPGPPRTFPSAPPRASGSHGSLLLPPASSPPPPQ 1064
Query: 67 APSSRFRVVKLPHGLGEPYR-----------RGRWTCVDVYERDLEPHSFGGLLEG---I 112
P R P L + + G T R PHS G +
Sbjct: 1065 VPQRRGTPPLTPGRLTQDLKLISASQPALPQDGAQTL-----RRASPHSSGESMAAFPLF 1119
Query: 113 RGASGGAGGRSLDSRLELASLGLGAPTPPSG--------LSQGPTSWLRPPPTSPGPQAR 164
A GG+GG +S GLG P P G L + +S PPP S
Sbjct: 1120 PRAGGGSGGSG-------SSGGLGPPGRPYGAIPGQHVTLPRKTSSGSLPPPLSLFGARA 1172
Query: 165 SFTGGLGQLVVPSKAKAEKPPLSASSPQQRP---PEP 198
+ +GG PPL+A PQ+ P PEP
Sbjct: 1173 TSSGG--------------PPLTA-GPQREPGARPEP 1194
Score = 32.0 bits (71), Expect = 1.00
Identities = 43/170 (25%), Positives = 59/170 (34%), Gaps = 28/170 (16%)
Query: 111 GIRGASGGAGGRSLDSRLELASLGLGAPTPPSGLSQGPTSWLRPPPTSPG---PQARSFT 167
G+ G R L L LG+ +P S SQ T P+S Q F+
Sbjct: 813 GLGNLGAGQTPRHLKRLQSLIPSALGSASPASSPSQVDT------PSSSSFHIQQLAGFS 866
Query: 168 GGLGQLVVPSKAKAEKPPLSASSPQQRPPEPETGESA-------------GTSRAATPLP 214
G + + + PP + SP P P G +A G S +++ P
Sbjct: 867 APAGLSPLLPSSSSSPPPGACGSPSA--PTPSAGVAATTIAGFGHFHKALGGSLSSSDSP 924
Query: 215 SLRVEAEAGGSGARTPPLSRRKAVDMRLRMELGAPEEMGQVPPLDSRPSS 264
L GAR+P ++ R LG PE PP PSS
Sbjct: 925 LLTPLQP----GARSPQAAQPSPAPPGARGGLGLPEHFLPPPPSSRSPSS 970
>gi|110349772 alpha 1 type I collagen preproprotein [Homo sapiens]
Length = 1464
Score = 52.0 bits (123), Expect = 9e-07
Identities = 69/224 (30%), Positives = 79/224 (35%), Gaps = 42/224 (18%)
Query: 22 PGSPGASDPPTPQPPTGPP-PRLPNGEPSPDPGGKG-TPRNGSPPPGAPSSRFRVVKLPH 79
PG PGA P PQ P GPP P+ +GEP PG KG T G P P V P
Sbjct: 409 PGFPGARGPSGPQGPGGPPGPKGNSGEPGA-PGSKGDTGAKGEPGP------VGVQGPPG 461
Query: 80 GLGEPYRRGRWTCVDVYERDLEPHSFGGLLEGIRGASGGAGGRSLDSRLELASLGLGAPT 139
GE +RG EP G L G G GG G R + G+ P
Sbjct: 462 PAGEEGKRGARG---------EPGPTG--LPGPPGERGGPGSRGFP-----GADGVAGPK 505
Query: 140 PPSGL--SQGPTSWLRPPPTSPG----------PQARSFTGGLGQLVVPSKAKAEKPPLS 187
P+G S GP P SPG P A+ TG G K P
Sbjct: 506 GPAGERGSPGPAG----PKGSPGEAGRPGEAGLPGAKGLTGSPGSPGPDGKTGPPGPAGQ 561
Query: 188 ASSPQQRPPEPETGESAGTSRAATPLPSLRVEAEAGGSGARTPP 231
P P G+ AG P + +AG G PP
Sbjct: 562 DGRPGPPGPPGARGQ-AGVMGFPGPKGAAGEPGKAGERGVPGPP 604
Score = 51.6 bits (122), Expect = 1e-06
Identities = 69/217 (31%), Positives = 88/217 (40%), Gaps = 28/217 (12%)
Query: 22 PGSPGASDPPTPQPPTGPPPRLPNGEPSPDPGGKGTPRNGSPPPGAPSSRFRVVKLPHGL 81
PG PGAS P P+ P GPP + NG+ + G G P PPG +R LP
Sbjct: 208 PGEPGASGPMGPRGPPGPPGK--NGDDG-EAGKPGRPGERG-PPGPQGAR----GLPGTA 259
Query: 82 GEPYRRGR--WTCVDVYERDLEPHSFGGL--LEGIRGASGGAGGRSLDSRLELASLGLGA 137
G P +G ++ +D + D P G G GA G G R L E G
Sbjct: 260 GLPGMKGHRGFSGLDGAKGDAGPAGPKGEPGSPGENGAPGQMGPRGLPG--ERGRPGAPG 317
Query: 138 PTPPSGLSQGPTSWLRPP-PTSP-GPQARSFTGGLGQLVVPSKAKA-EKPPLSASSPQQR 194
P G + G T PP PT P GP F G +G +K +A + P + PQ
Sbjct: 318 PAGARG-NDGATGAAGPPGPTGPAGPP--GFPGAVG-----AKGEAGPQGPRGSEGPQGV 369
Query: 195 PPEPETGESAGTSRAATPLPSLRVEAEAGGSGARTPP 231
EP AG AA P + + + G GA P
Sbjct: 370 RGEPGPPGPAG---AAGPAGNPGADGQPGAKGANGAP 403
Score = 43.5 bits (101), Expect = 3e-04
Identities = 74/263 (28%), Positives = 95/263 (36%), Gaps = 66/263 (25%)
Query: 16 TTDYEGPGSPGASDPPTPQPPTGPPPRLPNGEPSPDPGGKGTPRNGSPPPGAPSSRFRVV 75
TT EGP G + P P+ P GPP R +G P PG G P PPG P
Sbjct: 107 TTGVEGP--KGDTGPRGPRGPAGPPGR--DGIPG-QPGLPGPP----GPPGPPG------ 151
Query: 76 KLPHGLGEPYRRGRWTCVDVYERDLEPHSFGGLLEGIRGASGGAGGRSLDSRLELASLGL 135
P GLG G + Y D S GG+ + G G +G R
Sbjct: 152 --PPGLG-----GNFAPQLSYGYD--EKSTGGI--SVPGPMGPSGPR------------- 187
Query: 136 GAPTPPSGLSQGPTSWLRPPPTSPGPQARSFTGGLGQLVVPSKAKAEKPPLSASSPQQR- 194
G P PP + GP + PP P A G G P K + P +R
Sbjct: 188 GLPGPPG--APGPQGFQGPPGEPGEPGASGPMGPRGPPGPPGKNGDDGEAGKPGRPGERG 245
Query: 195 PPEPETGESAGTSRAATPLPSLR----------VEAEAGGSGARTPPLSRRKAVDMRLRM 244
PP P + A LP ++ + +AG +G + P S
Sbjct: 246 PPGP---QGARGLPGTAGLPGMKGHRGFSGLDGAKGDAGPAGPKGEPGSPG--------- 293
Query: 245 ELGAPEEMGQ--VPPLDSRPSSP 265
E GAP +MG +P RP +P
Sbjct: 294 ENGAPGQMGPRGLPGERGRPGAP 316
Score = 43.5 bits (101), Expect = 3e-04
Identities = 60/221 (27%), Positives = 76/221 (34%), Gaps = 42/221 (19%)
Query: 22 PGSPGASDPPTPQPPTGPPPRLPNGEPSPDPGGKGTPRNGSPPPGAPSSRFRVVKLPHGL 81
PG G PP P P G NG P D G KG + PGAP S+ P
Sbjct: 682 PGERGVQGPPGPAGPRG-----ANGAPGND-GAKG----DAGAPGAPGSQ----GAPGLQ 727
Query: 82 GEPYRRGRWTCVDVYERDLEPHSFGGLLEGIRGASGGAGGRSLD-SRLELASLGLGAPTP 140
G P RG L G +G G AG + D S + GL P
Sbjct: 728 GMPGERG-----------------AAGLPGPKGDRGDAGPKGADGSPGKDGVRGLTGPIG 770
Query: 141 PSGLSQGPTSWLRPPPTSP-GPQ-ARSFTGGLGQLVVPSKAKAEKPPLSASSPQQRPPEP 198
P G + P P+ P GP AR G G+ P A PP + P +
Sbjct: 771 PPGPAGAPGDKGESGPSGPAGPTGARGAPGDRGEPGPPGPAGFAGPPGADGQPGAKGEPG 830
Query: 199 ETGES--------AGTSRAATPLPSLRVEAEAGGSGARTPP 231
+ G AG + P+ ++ G G+ PP
Sbjct: 831 DAGAKGDAGPPGPAGPAGPPGPIGNVGAPGAKGARGSAGPP 871
Score = 43.1 bits (100), Expect = 4e-04
Identities = 73/252 (28%), Positives = 90/252 (35%), Gaps = 47/252 (18%)
Query: 22 PGSPGASDPPTPQPPTGPPPRLPNGEPSPDPGGKGTPRNGSPPPGAPSSRFRVVKLPHGL 81
PG+ G PP P GPP P G P+ GGKG PR + P G P V P
Sbjct: 877 PGAAGRVGPPGPSGNAGPPG--PPG-PAGKEGGKG-PRGETGPAGRPGE----VGPPGPP 928
Query: 82 GEPYRRGRWTCVDVYERDLEPHSFGGL-LEGIRGASGGAGGRSL----DSRLELASLGLG 136
G +G P + G G G G AG R + R E GL
Sbjct: 929 GPAGEKG------------SPGADGPAGAPGTPGPQGIAGQRGVVGLPGQRGERGFPGLP 976
Query: 137 APTPPSGLSQGPT--SWLRPPPTSPGPQARSFTGGLGQLVVPSKAKAEKPPLSASSPQQR 194
P+ G QGP+ S R PP GP G P ++ E P + SP +
Sbjct: 977 GPSGEPG-KQGPSGASGERGPPGPMGPP--------GLAGPPGESGREGAPGAEGSPGRD 1027
Query: 195 PPEPETGESAGTSRAATPLPSLRVEAEAGGSGARTPPLSRRKAVDMRLRMELGAPEEMGQ 254
G+ T A P G GA P K+ D R E G G
Sbjct: 1028 GSPGAKGDRGETGPAGPP-------GAPGAPGAPGPVGPAGKSGD---RGETGPAGPAGP 1077
Query: 255 VPPLDSR-PSSP 265
V P+ +R P+ P
Sbjct: 1078 VGPVGARGPAGP 1089
Score = 42.4 bits (98), Expect = 7e-04
Identities = 73/258 (28%), Positives = 84/258 (32%), Gaps = 48/258 (18%)
Query: 22 PGSPGASDPPTPQPPTGPP-------PRLPNGEPS--------PDPGGKGTPRNGSPPPG 66
PG PG PP P P GPP P+L G P P G PR PPG
Sbjct: 135 PGQPGLPGPPGPPGPPGPPGLGGNFAPQLSYGYDEKSTGGISVPGPMGPSGPRGLPGPPG 194
Query: 67 APSSRFRVVKLPHGL-GEPYRRGRWTCVDVYERDLEPHSFGGLLEGIRGASGGAGGRSLD 125
AP P G G P G EP + G + G RG G G D
Sbjct: 195 APG--------PQGFQGPPGEPG------------EPGASGPM--GPRGPPGPPGKNGDD 232
Query: 126 SRL-ELASLGLGAPTPPSGLSQGP-TSWLRPPPTSPGPQARSFTGGLGQLVVPSKAKAEK 183
+ G P P G P T+ L P G + S G P+ K E
Sbjct: 233 GEAGKPGRPGERGPPGPQGARGLPGTAGL---PGMKGHRGFSGLDGAKGDAGPAGPKGEP 289
Query: 184 -PPLSASSPQQRPPEPETGESAGTSRAATPLPSLRVEAEAGGSGARTPPLSRRKAVDMRL 242
P +P Q P GE R P P+ G +GA PP A
Sbjct: 290 GSPGENGAPGQMGPRGLPGE---RGRPGAPGPA-GARGNDGATGAAGPPGPTGPAGPPGF 345
Query: 243 RMELGAPEEMGQVPPLDS 260
+GA E G P S
Sbjct: 346 PGAVGAKGEAGPQGPRGS 363
Score = 39.7 bits (91), Expect = 0.005
Identities = 36/105 (34%), Positives = 43/105 (40%), Gaps = 13/105 (12%)
Query: 22 PGSPGASDPPTPQPPTGPPPRLPNGEPSPDPGGKGTPRNGSPPPGAPSSRFRVVKLPHGL 81
PG G + P P P GP R + P PG G P PPG PS+ F LP
Sbjct: 1150 PGKDGLNGLPGPIGPPGPRGRTGDAGPVGPPGPPGPP----GPPGPPSAGFDFSFLPQPP 1205
Query: 82 GE-PYRRGRWTCVD----VYERDLEP----HSFGGLLEGIRGASG 117
E + GR+ D V +RDLE S +E IR G
Sbjct: 1206 QEKAHDGGRYYRADDANVVRDRDLEVDTTLKSLSQQIENIRSPEG 1250
Score = 35.8 bits (81), Expect = 0.069
Identities = 69/251 (27%), Positives = 85/251 (33%), Gaps = 48/251 (19%)
Query: 23 GSPGASDPPTPQPPTGPPPRLPNGEPSP--DPGGKGTPRNGSPP--PGAPSSRFRVVKLP 78
G GA PP P P G GE P PG +G P PP G P + +P
Sbjct: 614 GEAGAQGPPGPAGPAGE-----RGEQGPAGSPGFQGLPGPAGPPGEAGKPGEQ----GVP 664
Query: 79 HGLGEPYRRGRWTCVDVYERDLEPHSFGGLLEGIRGASGGAGGRSLDSR--LELASLGLG 136
LG P G F G G++G G AG R + + A G
Sbjct: 665 GDLGAPGPSGA----------RGERGFPG-ERGVQGPPGPAGPRGANGAPGNDGAKGDAG 713
Query: 137 APTPPSGLSQGPTSWLRPPPTSPGPQARSFTGGLGQLVVPSKAKAEKPPLSA-SSPQQRP 195
AP P SQG +PG Q G L P + + P A SP +
Sbjct: 714 APGAPG--SQG----------APGLQGMPGERGAAGLPGPKGDRGDAGPKGADGSPGKDG 761
Query: 196 PEPETGESAGTSRAATPLPSLRVEAEAGGSGARTPPLSRRKAVDMRLRMELGAPEEMGQV 255
TG A P + E+G SG P +R D R E G P G
Sbjct: 762 VRGLTGPIGPPGPAGAP----GDKGESGPSGPAGPTGARGAPGD---RGEPGPPGPAGFA 814
Query: 256 --PPLDSRPSS 264
P D +P +
Sbjct: 815 GPPGADGQPGA 825
>gi|162329583 cleavage and polyadenylation specific factor 6, 68 kD
subunit [Homo sapiens]
Length = 551
Score = 51.6 bits (122), Expect = 1e-06
Identities = 60/206 (29%), Positives = 69/206 (33%), Gaps = 48/206 (23%)
Query: 22 PGS-PGASDPPTPQPPTGPPPRLPNGEPSP-----DPGGKGTPRNGSPPPGAPSSRFRVV 75
PG+ PG P P P GPPP P G+ P PG G P G PPPG
Sbjct: 208 PGAVPGGDRFPGPAGPGGPPPPFPAGQTPPRPPLGPPGPPGPP--GPPPPGQ-------- 257
Query: 76 KLPHGLGEPYRRGRWTCVDVYERDLEPHSFGGLLEGIRGASGGAGGRSLDSRLELASLGL 135
LP L P RG +R P F G G + L L
Sbjct: 258 VLPPPLAGPPNRG--------DRPPPPVLFPGQPFG---------------QPPLGPLPP 294
Query: 136 GAPTPPSGLS--QGPTSWLRPPPTSPGPQARSFTGGLGQLV-------VPSKAKAEKPPL 186
G P P G GP + PP PGP G LG + +P PP
Sbjct: 295 GPPPPVPGYGPPPGPPPPQQGPPPPPGPFPPRPPGPLGPPLTLAPPPHLPGPPPGAPPPA 354
Query: 187 SASSPQQRPPEPETGESAGTSRAATP 212
+P PP +G SR P
Sbjct: 355 PHVNPAFFPPPTNSGMPTSDSRGPPP 380
Score = 37.7 bits (86), Expect = 0.018
Identities = 28/80 (35%), Positives = 31/80 (38%), Gaps = 11/80 (13%)
Query: 20 EGPGSPGASDPPTPQPPTG------PPPRLPNGEPSPDPGGKGTPRNGSPPP---GAPSS 70
+GP P PP P P G PPP LP P P PPP G P+S
Sbjct: 314 QGPPPPPGPFPPRPPGPLGPPLTLAPPPHLPGPPPGAPPPAPHVNPAFFPPPTNSGMPTS 373
Query: 71 RFR--VVKLPHGLGEPYRRG 88
R P+G PY RG
Sbjct: 374 DSRGPPPTDPYGRPPPYDRG 393
Score = 32.0 bits (71), Expect = 1.00
Identities = 21/55 (38%), Positives = 22/55 (40%), Gaps = 18/55 (32%)
Query: 22 PGSPGASDPPTPQ-------PPT----------GPPPRLPNGEPSP-DPGGKGTP 58
PG P + PP P PPT GPPP P G P P D G G P
Sbjct: 344 PGPPPGAPPPAPHVNPAFFPPPTNSGMPTSDSRGPPPTDPYGRPPPYDRGDYGPP 398
Score = 31.2 bits (69), Expect = 1.7
Identities = 21/51 (41%), Positives = 21/51 (41%), Gaps = 4/51 (7%)
Query: 21 GPGSPGASDPPT---PQPPTGPPPRLPNGEPSPDPGGKGTPRNGSPPPGAP 68
G G P PP P PP PPR P G P P PPPGAP
Sbjct: 302 GYGPPPGPPPPQQGPPPPPGPFPPR-PPGPLGPPLTLAPPPHLPGPPPGAP 351
>gi|110832843 TBP-associated factor 4 [Homo sapiens]
Length = 1085
Score = 51.2 bits (121), Expect = 2e-06
Identities = 58/221 (26%), Positives = 77/221 (34%), Gaps = 16/221 (7%)
Query: 21 GPGSPGASDPPTPQPPTGPPPRLPNGEPSPDPGGKGTPRNGSPPPGAPSSRFRVVKLPHG 80
GP PG P P P GP P P P+ G+ + +P P A + P G
Sbjct: 101 GPQRPGPPSPRRPLVPAGPAPPAAKLRPPPE----GSAGSCAPVPAAAAVAAGPEPAPAG 156
Query: 81 LGEPYRRGRWTCVDVYERDLEPHSFGGLLEGIRGASGGAGGRSLDSRLELASLGLGAPTP 140
+P G P G G +G ++L+ L + A
Sbjct: 157 PAKP--AGPAALAARAGPGPGPGPGPGPGPGPGKPAGPGAAQTLNGSAALLNSHHAAAPA 214
Query: 141 PSGLSQGPTSWL-RPPPTSPGP--QARSFTGGLG--QLVVPSKAKAEKPPLSASSPQQRP 195
S ++ GP + L P P +PG Q F G PS A P A++P P
Sbjct: 215 VSLVNNGPAALLPLPKPAAPGTVIQTPPFVGAAAPPAPAAPSPPAAPAPAAPAAAPPPPP 274
Query: 196 PEPET-----GESAGTSRAATPLPSLRVEAEAGGSGARTPP 231
P P T G AG AA +P G +GA P
Sbjct: 275 PAPATLARPPGHPAGPPTAAPAVPPPAAAQNGGSAGAAPAP 315
Score = 37.0 bits (84), Expect = 0.031
Identities = 60/255 (23%), Positives = 86/255 (33%), Gaps = 31/255 (12%)
Query: 30 PPTPQPPTGPPPRLPNGEPSPDPGGKGTPRNGSPPPGAPSSRFRVVKLPHGLGEPYRRGR 89
P P P GP P P PG P G P P + + +G
Sbjct: 154 PAGPAKPAGPAALAARAGPGPGPGPGPGPGPGPGKPAGPGA----AQTLNGSAALLNSHH 209
Query: 90 WTCVDVYERDLEPHSFGGLLEGIRGASGGAGGRSLDSRLELASLGLGAPTPPSGLSQG-P 148
V L + LL + A+ G ++ A AP+PP+ + P
Sbjct: 210 AAAPAV---SLVNNGPAALLPLPKPAAPGTVIQTPPFVGAAAPPAPAAPSPPAAPAPAAP 266
Query: 149 TSWLRPPPTSPGPQARSFTGGLGQLVVPSKAKAEKPPLSA----SSPQQRPPEPETGESA 204
+ PPP +P AR G P+ A A PP +A S+ P P G A
Sbjct: 267 AAAPPPPPPAPATLARPPGHPAGP---PTAAPAVPPPAAAQNGGSAGAAPAPAPAAGGPA 323
Query: 205 GTS-------RAATPLPSLRVEA---------EAGGSGARTPPLSRRKAVDMRLRMELGA 248
G S AA P P ++ E+ A + A + P S ++ + M+
Sbjct: 324 GVSGQPGPGAAAAAPAPGVKAESPKRVVQAAPPAAQTLAASGPASTAASMVIGPTMQGAL 383
Query: 249 PEEMGQVPPLDSRPS 263
P PP P+
Sbjct: 384 PSPAAVPPPAPGTPT 398
Score = 34.7 bits (78), Expect = 0.15
Identities = 19/54 (35%), Positives = 23/54 (42%), Gaps = 5/54 (9%)
Query: 16 TTDYEGPGSPGASDPPTPQPPTGPPPRLPNGEPSPDPGGKGTPRNGSPPPGAPS 69
T + G +P A P P PP P P P P P P P + PPG P+
Sbjct: 240 TPPFVGAAAPPA--PAAPSPPAAPAPAAPAAAPPPPP---PAPATLARPPGHPA 288
>gi|166706868 synaptopodin 2-like isoform a [Homo sapiens]
Length = 977
Score = 51.2 bits (121), Expect = 2e-06
Identities = 70/233 (30%), Positives = 88/233 (37%), Gaps = 52/233 (22%)
Query: 26 GASDPPTPQPPTGPPPRLPNGEPSPDPGGKGTPRNGSPPPGAPSSRFRVVKLPHGLGEPY 85
G PP Q PP PSP P +PR P GAP+
Sbjct: 418 GLQSPPRAQ---SAPPEAAVLPPSPLPAPVASPRPFQPGGGAPTP--------------- 459
Query: 86 RRGRWTCVDVYERDLEPHSFGGLLEGIRGASGGAGGRSLDSRLELASLGLGAPTPPSGLS 145
++ R P + G L+G R + R L + SLG +P PP LS
Sbjct: 460 ------APSIFNRSARPFTPG--LQGQRPTTTSVIFRPLAPKRANDSLGGLSPAPPPFLS 511
Query: 146 -QGPTSWLRPPPTSPGPQARSFTGGLGQLVVPSKAKAEKPPLSASS----PQQRP----- 195
QGPT P TS P +G PS ++ P + SS RP
Sbjct: 512 SQGPTPL--PSFTSGVPSHAPVSGS------PSTPRSSGPVTATSSLYIPAPSRPVTPGG 563
Query: 196 -PEPETGESAG--TSRAA----TPL-PSLRVEAEAGGSGARTPPLSRRKAVDM 240
PEP SA TS A+ PL PS R EA A G GA PP +R + + +
Sbjct: 564 APEPPAPPSAAAMTSTASIFLSAPLRPSARPEAPAPGPGAPEPPSAREQRISV 616
Score = 35.0 bits (79), Expect = 0.12
Identities = 16/34 (47%), Positives = 19/34 (55%)
Query: 32 TPQPPTGPPPRLPNGEPSPDPGGKGTPRNGSPPP 65
TP P GP PR P+ PS P K +P +PPP
Sbjct: 777 TPGPGLGPRPRSPSPTPSLPPSWKYSPNIRAPPP 810
Score = 34.7 bits (78), Expect = 0.15
Identities = 39/145 (26%), Positives = 50/145 (34%), Gaps = 17/145 (11%)
Query: 126 SRLELASL--GLGAPTPPSGLSQGPTSWLRPPPTSPGPQA--RSF-TGGLGQLVVPSKAK 180
+R+E A++ G G +PP S P + + PP P P A R F GG PS
Sbjct: 406 ARVEPAAMLNGEGLQSPPRAQSAPPEAAVLPPSPLPAPVASPRPFQPGGGAPTPAPSIFN 465
Query: 181 AEKPPLSASSPQQRPPEPETGESAGTSRAATPLPSLRVEAEAGGSGARTPPLSRRKAVDM 240
P + QRP TS PL R GG PP +
Sbjct: 466 RSARPFTPGLQGQRP--------TTTSVIFRPLAPKRANDSLGGLSPAPPPFLSSQGPTP 517
Query: 241 RLRMELGAPEEMGQVPPLDSRPSSP 265
G P P+ PS+P
Sbjct: 518 LPSFTSGVPSH----APVSGSPSTP 538
Score = 28.9 bits (63), Expect = 8.5
Identities = 17/52 (32%), Positives = 19/52 (36%), Gaps = 2/52 (3%)
Query: 20 EGPGSPGASDPPTPQPPTGPPPR--LPNGEPSPDPGGKGTPRNGSPPPGAPS 69
E P P P P PP PP L + P P G P G +PS
Sbjct: 152 EKPRRPRRRGPTRPTPPGAPPDEVYLSDSPAEPAPTIPGPPSQGDSRVSSPS 203
>gi|50301232 synaptopodin 2-like isoform b [Homo sapiens]
Length = 753
Score = 51.2 bits (121), Expect = 2e-06
Identities = 70/233 (30%), Positives = 88/233 (37%), Gaps = 52/233 (22%)
Query: 26 GASDPPTPQPPTGPPPRLPNGEPSPDPGGKGTPRNGSPPPGAPSSRFRVVKLPHGLGEPY 85
G PP Q PP PSP P +PR P GAP+
Sbjct: 194 GLQSPPRAQ---SAPPEAAVLPPSPLPAPVASPRPFQPGGGAPTP--------------- 235
Query: 86 RRGRWTCVDVYERDLEPHSFGGLLEGIRGASGGAGGRSLDSRLELASLGLGAPTPPSGLS 145
++ R P + G L+G R + R L + SLG +P PP LS
Sbjct: 236 ------APSIFNRSARPFTPG--LQGQRPTTTSVIFRPLAPKRANDSLGGLSPAPPPFLS 287
Query: 146 -QGPTSWLRPPPTSPGPQARSFTGGLGQLVVPSKAKAEKPPLSASS----PQQRP----- 195
QGPT P TS P +G PS ++ P + SS RP
Sbjct: 288 SQGPTPL--PSFTSGVPSHAPVSGS------PSTPRSSGPVTATSSLYIPAPSRPVTPGG 339
Query: 196 -PEPETGESAG--TSRAA----TPL-PSLRVEAEAGGSGARTPPLSRRKAVDM 240
PEP SA TS A+ PL PS R EA A G GA PP +R + + +
Sbjct: 340 APEPPAPPSAAAMTSTASIFLSAPLRPSARPEAPAPGPGAPEPPSAREQRISV 392
Score = 35.0 bits (79), Expect = 0.12
Identities = 16/34 (47%), Positives = 19/34 (55%)
Query: 32 TPQPPTGPPPRLPNGEPSPDPGGKGTPRNGSPPP 65
TP P GP PR P+ PS P K +P +PPP
Sbjct: 553 TPGPGLGPRPRSPSPTPSLPPSWKYSPNIRAPPP 586
Score = 34.7 bits (78), Expect = 0.15
Identities = 39/145 (26%), Positives = 50/145 (34%), Gaps = 17/145 (11%)
Query: 126 SRLELASL--GLGAPTPPSGLSQGPTSWLRPPPTSPGPQA--RSF-TGGLGQLVVPSKAK 180
+R+E A++ G G +PP S P + + PP P P A R F GG PS
Sbjct: 182 ARVEPAAMLNGEGLQSPPRAQSAPPEAAVLPPSPLPAPVASPRPFQPGGGAPTPAPSIFN 241
Query: 181 AEKPPLSASSPQQRPPEPETGESAGTSRAATPLPSLRVEAEAGGSGARTPPLSRRKAVDM 240
P + QRP TS PL R GG PP +
Sbjct: 242 RSARPFTPGLQGQRP--------TTTSVIFRPLAPKRANDSLGGLSPAPPPFLSSQGPTP 293
Query: 241 RLRMELGAPEEMGQVPPLDSRPSSP 265
G P P+ PS+P
Sbjct: 294 LPSFTSGVPSH----APVSGSPSTP 314
>gi|149158696 HLA-B associated transcript-3 isoform b [Homo sapiens]
Length = 1126
Score = 50.8 bits (120), Expect = 2e-06
Identities = 64/243 (26%), Positives = 94/243 (38%), Gaps = 42/243 (17%)
Query: 26 GASDPPTPQPPTGPPPRLPNGEPSPDPGGKGTPRNGSPPPG-AP---SSRFRVVKLPHGL 81
G PPTP PP +P + G+PPPG AP +S RV+++ H
Sbjct: 385 GTRPPPTPNAEAPPPGPGQASSVAPSSTNVESSAEGAPPPGPAPPPATSHPRVIRISHQS 444
Query: 82 GEPYRRGRWTCVDVYERDLEPHSFGGLLEGIRGASGGAG-GRSLDSRL-----ELASLGL 135
EP +++ + +P GG+ G G G G++L ++ + +
Sbjct: 445 VEPVVMMH---MNIQDSGTQP---GGVPSAPTGPLGPPGHGQTLGQQVPGFPTAPTRVVI 498
Query: 136 GAPTPPSGLSQGPTSWLRPPPTSPGPQ----------ARSFTGGLGQLVVPSKAKAEKPP 185
PTPP P PP S Q A+ +G +GQL++ A+ P
Sbjct: 499 ARPTPPQARPSHPGG----PPVSGTLQGAGLGTNASLAQMVSGLVGQLLMQPVLVAQGTP 554
Query: 186 LSASSPQQRPPEPETGE-SAGTSRAATPLPSLRVEAEAGGSGARTPPLSRRKAVDMRLRM 244
A PP P T SAGT+ AT A G A+ PP + D++
Sbjct: 555 GMAP-----PPAPATASASAGTTNTAT------TAGPAPGGPAQPPPTPQPSMADLQFSQ 603
Query: 245 ELG 247
LG
Sbjct: 604 LLG 606
Score = 33.5 bits (75), Expect = 0.34
Identities = 15/36 (41%), Positives = 18/36 (50%), Gaps = 3/36 (8%)
Query: 31 PTPQPPTGPPPRLPNGEPSPDPGGKGTPRNGSPPPG 66
P P PP PPP P + P P G+P G+ PG
Sbjct: 651 PPPPPPPPPPPPAPEQQTMPPP---GSPSGGAGSPG 683
Score = 32.0 bits (71), Expect = 1.00
Identities = 45/169 (26%), Positives = 56/169 (33%), Gaps = 54/169 (31%)
Query: 23 GSPGASDPPTPQPPTGPPPRLPNGEPSPDPGGKGTPRNGSPPPGAPSSRFRVVKLPHGLG 82
G+PG + PP P S G T P PG P+ P
Sbjct: 552 GTPGMAPPPAP------------ATASASAGTTNTATTAGPAPGGPAQ-------PPPTP 592
Query: 83 EPYRRGRWTCVDVYERDLEPHSFGGLLEGIRGASG-GAGGRSLDS-RLELASLGLGA--- 137
+P DL+ F LL + G +G GAGG + S + +A G+ A
Sbjct: 593 QPSMA-----------DLQ---FSQLLGNLLGPAGPGAGGSGVASPTITVAMPGVPAFLQ 638
Query: 138 ---------------PTPPSGLSQGPTSWLRPPPTSPGPQARSFTGGLG 171
P PP P PPP SP A S GGLG
Sbjct: 639 GMTDFLQATQTAPPPPPPPPPPPPAPEQQTMPPPGSPSGGAGS-PGGLG 686
Score = 30.8 bits (68), Expect = 2.2
Identities = 15/35 (42%), Positives = 18/35 (51%), Gaps = 1/35 (2%)
Query: 22 PGSPGASDPPTPQPPTGPPPRLPNGEPSPDPGGKG 56
P P PP P+ T PPP P+G + PGG G
Sbjct: 653 PPPPPPPPPPAPEQQTMPPPGSPSG-GAGSPGGLG 686
Score = 30.4 bits (67), Expect = 2.9
Identities = 34/129 (26%), Positives = 48/129 (37%), Gaps = 35/129 (27%)
Query: 12 ITSVTTDYEGPGSP----GASD----PPTPQPPTGPPPRLPNGEPSPDPGGKGTPRNGSP 63
+ S T PG P G +D T PP PPP P P+P+ + P
Sbjct: 621 VASPTITVAMPGVPAFLQGMTDFLQATQTAPPPPPPPPPPP---PAPE-------QQTMP 670
Query: 64 PPGAPSSRFRVVKLPHGLGEPYRRGRWTCVDVYERDLEPHSFGGLLEGIRGASGGAGGRS 123
PPG+PS G G P G L P F +++G+ + G+ G
Sbjct: 671 PPGSPSG---------GAGSPGGLGL--------ESLSPEFFTSVVQGVLSSLLGSLGAR 713
Query: 124 LDSRLELAS 132
S +A+
Sbjct: 714 AGSSESIAA 722
>gi|18375632 HLA-B associated transcript-3 isoform b [Homo sapiens]
Length = 1126
Score = 50.8 bits (120), Expect = 2e-06
Identities = 64/243 (26%), Positives = 94/243 (38%), Gaps = 42/243 (17%)
Query: 26 GASDPPTPQPPTGPPPRLPNGEPSPDPGGKGTPRNGSPPPG-AP---SSRFRVVKLPHGL 81
G PPTP PP +P + G+PPPG AP +S RV+++ H
Sbjct: 385 GTRPPPTPNAEAPPPGPGQASSVAPSSTNVESSAEGAPPPGPAPPPATSHPRVIRISHQS 444
Query: 82 GEPYRRGRWTCVDVYERDLEPHSFGGLLEGIRGASGGAG-GRSLDSRL-----ELASLGL 135
EP +++ + +P GG+ G G G G++L ++ + +
Sbjct: 445 VEPVVMMH---MNIQDSGTQP---GGVPSAPTGPLGPPGHGQTLGQQVPGFPTAPTRVVI 498
Query: 136 GAPTPPSGLSQGPTSWLRPPPTSPGPQ----------ARSFTGGLGQLVVPSKAKAEKPP 185
PTPP P PP S Q A+ +G +GQL++ A+ P
Sbjct: 499 ARPTPPQARPSHPGG----PPVSGTLQGAGLGTNASLAQMVSGLVGQLLMQPVLVAQGTP 554
Query: 186 LSASSPQQRPPEPETGE-SAGTSRAATPLPSLRVEAEAGGSGARTPPLSRRKAVDMRLRM 244
A PP P T SAGT+ AT A G A+ PP + D++
Sbjct: 555 GMAP-----PPAPATASASAGTTNTAT------TAGPAPGGPAQPPPTPQPSMADLQFSQ 603
Query: 245 ELG 247
LG
Sbjct: 604 LLG 606
Score = 33.5 bits (75), Expect = 0.34
Identities = 15/36 (41%), Positives = 18/36 (50%), Gaps = 3/36 (8%)
Query: 31 PTPQPPTGPPPRLPNGEPSPDPGGKGTPRNGSPPPG 66
P P PP PPP P + P P G+P G+ PG
Sbjct: 651 PPPPPPPPPPPPAPEQQTMPPP---GSPSGGAGSPG 683
Score = 32.0 bits (71), Expect = 1.00
Identities = 45/169 (26%), Positives = 56/169 (33%), Gaps = 54/169 (31%)
Query: 23 GSPGASDPPTPQPPTGPPPRLPNGEPSPDPGGKGTPRNGSPPPGAPSSRFRVVKLPHGLG 82
G+PG + PP P S G T P PG P+ P
Sbjct: 552 GTPGMAPPPAP------------ATASASAGTTNTATTAGPAPGGPAQ-------PPPTP 592
Query: 83 EPYRRGRWTCVDVYERDLEPHSFGGLLEGIRGASG-GAGGRSLDS-RLELASLGLGA--- 137
+P DL+ F LL + G +G GAGG + S + +A G+ A
Sbjct: 593 QPSMA-----------DLQ---FSQLLGNLLGPAGPGAGGSGVASPTITVAMPGVPAFLQ 638
Query: 138 ---------------PTPPSGLSQGPTSWLRPPPTSPGPQARSFTGGLG 171
P PP P PPP SP A S GGLG
Sbjct: 639 GMTDFLQATQTAPPPPPPPPPPPPAPEQQTMPPPGSPSGGAGS-PGGLG 686
Score = 30.8 bits (68), Expect = 2.2
Identities = 15/35 (42%), Positives = 18/35 (51%), Gaps = 1/35 (2%)
Query: 22 PGSPGASDPPTPQPPTGPPPRLPNGEPSPDPGGKG 56
P P PP P+ T PPP P+G + PGG G
Sbjct: 653 PPPPPPPPPPAPEQQTMPPPGSPSG-GAGSPGGLG 686
Score = 30.4 bits (67), Expect = 2.9
Identities = 34/129 (26%), Positives = 48/129 (37%), Gaps = 35/129 (27%)
Query: 12 ITSVTTDYEGPGSP----GASD----PPTPQPPTGPPPRLPNGEPSPDPGGKGTPRNGSP 63
+ S T PG P G +D T PP PPP P P+P+ + P
Sbjct: 621 VASPTITVAMPGVPAFLQGMTDFLQATQTAPPPPPPPPPPP---PAPE-------QQTMP 670
Query: 64 PPGAPSSRFRVVKLPHGLGEPYRRGRWTCVDVYERDLEPHSFGGLLEGIRGASGGAGGRS 123
PPG+PS G G P G L P F +++G+ + G+ G
Sbjct: 671 PPGSPSG---------GAGSPGGLGL--------ESLSPEFFTSVVQGVLSSLLGSLGAR 713
Query: 124 LDSRLELAS 132
S +A+
Sbjct: 714 AGSSESIAA 722
>gi|18375630 HLA-B associated transcript-3 isoform b [Homo sapiens]
Length = 1126
Score = 50.8 bits (120), Expect = 2e-06
Identities = 64/243 (26%), Positives = 94/243 (38%), Gaps = 42/243 (17%)
Query: 26 GASDPPTPQPPTGPPPRLPNGEPSPDPGGKGTPRNGSPPPG-AP---SSRFRVVKLPHGL 81
G PPTP PP +P + G+PPPG AP +S RV+++ H
Sbjct: 385 GTRPPPTPNAEAPPPGPGQASSVAPSSTNVESSAEGAPPPGPAPPPATSHPRVIRISHQS 444
Query: 82 GEPYRRGRWTCVDVYERDLEPHSFGGLLEGIRGASGGAG-GRSLDSRL-----ELASLGL 135
EP +++ + +P GG+ G G G G++L ++ + +
Sbjct: 445 VEPVVMMH---MNIQDSGTQP---GGVPSAPTGPLGPPGHGQTLGQQVPGFPTAPTRVVI 498
Query: 136 GAPTPPSGLSQGPTSWLRPPPTSPGPQ----------ARSFTGGLGQLVVPSKAKAEKPP 185
PTPP P PP S Q A+ +G +GQL++ A+ P
Sbjct: 499 ARPTPPQARPSHPGG----PPVSGTLQGAGLGTNASLAQMVSGLVGQLLMQPVLVAQGTP 554
Query: 186 LSASSPQQRPPEPETGE-SAGTSRAATPLPSLRVEAEAGGSGARTPPLSRRKAVDMRLRM 244
A PP P T SAGT+ AT A G A+ PP + D++
Sbjct: 555 GMAP-----PPAPATASASAGTTNTAT------TAGPAPGGPAQPPPTPQPSMADLQFSQ 603
Query: 245 ELG 247
LG
Sbjct: 604 LLG 606
Score = 33.5 bits (75), Expect = 0.34
Identities = 15/36 (41%), Positives = 18/36 (50%), Gaps = 3/36 (8%)
Query: 31 PTPQPPTGPPPRLPNGEPSPDPGGKGTPRNGSPPPG 66
P P PP PPP P + P P G+P G+ PG
Sbjct: 651 PPPPPPPPPPPPAPEQQTMPPP---GSPSGGAGSPG 683
Score = 32.0 bits (71), Expect = 1.00
Identities = 45/169 (26%), Positives = 56/169 (33%), Gaps = 54/169 (31%)
Query: 23 GSPGASDPPTPQPPTGPPPRLPNGEPSPDPGGKGTPRNGSPPPGAPSSRFRVVKLPHGLG 82
G+PG + PP P S G T P PG P+ P
Sbjct: 552 GTPGMAPPPAP------------ATASASAGTTNTATTAGPAPGGPAQ-------PPPTP 592
Query: 83 EPYRRGRWTCVDVYERDLEPHSFGGLLEGIRGASG-GAGGRSLDS-RLELASLGLGA--- 137
+P DL+ F LL + G +G GAGG + S + +A G+ A
Sbjct: 593 QPSMA-----------DLQ---FSQLLGNLLGPAGPGAGGSGVASPTITVAMPGVPAFLQ 638
Query: 138 ---------------PTPPSGLSQGPTSWLRPPPTSPGPQARSFTGGLG 171
P PP P PPP SP A S GGLG
Sbjct: 639 GMTDFLQATQTAPPPPPPPPPPPPAPEQQTMPPPGSPSGGAGS-PGGLG 686
Score = 30.8 bits (68), Expect = 2.2
Identities = 15/35 (42%), Positives = 18/35 (51%), Gaps = 1/35 (2%)
Query: 22 PGSPGASDPPTPQPPTGPPPRLPNGEPSPDPGGKG 56
P P PP P+ T PPP P+G + PGG G
Sbjct: 653 PPPPPPPPPPAPEQQTMPPPGSPSG-GAGSPGGLG 686
Score = 30.4 bits (67), Expect = 2.9
Identities = 34/129 (26%), Positives = 48/129 (37%), Gaps = 35/129 (27%)
Query: 12 ITSVTTDYEGPGSP----GASD----PPTPQPPTGPPPRLPNGEPSPDPGGKGTPRNGSP 63
+ S T PG P G +D T PP PPP P P+P+ + P
Sbjct: 621 VASPTITVAMPGVPAFLQGMTDFLQATQTAPPPPPPPPPPP---PAPE-------QQTMP 670
Query: 64 PPGAPSSRFRVVKLPHGLGEPYRRGRWTCVDVYERDLEPHSFGGLLEGIRGASGGAGGRS 123
PPG+PS G G P G L P F +++G+ + G+ G
Sbjct: 671 PPGSPSG---------GAGSPGGLGL--------ESLSPEFFTSVVQGVLSSLLGSLGAR 713
Query: 124 LDSRLELAS 132
S +A+
Sbjct: 714 AGSSESIAA 722
>gi|149158692 HLA-B associated transcript-3 isoform a [Homo sapiens]
Length = 1132
Score = 50.8 bits (120), Expect = 2e-06
Identities = 64/243 (26%), Positives = 94/243 (38%), Gaps = 42/243 (17%)
Query: 26 GASDPPTPQPPTGPPPRLPNGEPSPDPGGKGTPRNGSPPPG-AP---SSRFRVVKLPHGL 81
G PPTP PP +P + G+PPPG AP +S RV+++ H
Sbjct: 391 GTRPPPTPNAEAPPPGPGQASSVAPSSTNVESSAEGAPPPGPAPPPATSHPRVIRISHQS 450
Query: 82 GEPYRRGRWTCVDVYERDLEPHSFGGLLEGIRGASGGAG-GRSLDSRL-----ELASLGL 135
EP +++ + +P GG+ G G G G++L ++ + +
Sbjct: 451 VEPVVMMH---MNIQDSGTQP---GGVPSAPTGPLGPPGHGQTLGQQVPGFPTAPTRVVI 504
Query: 136 GAPTPPSGLSQGPTSWLRPPPTSPGPQ----------ARSFTGGLGQLVVPSKAKAEKPP 185
PTPP P PP S Q A+ +G +GQL++ A+ P
Sbjct: 505 ARPTPPQARPSHPGG----PPVSGTLQGAGLGTNASLAQMVSGLVGQLLMQPVLVAQGTP 560
Query: 186 LSASSPQQRPPEPETGE-SAGTSRAATPLPSLRVEAEAGGSGARTPPLSRRKAVDMRLRM 244
A PP P T SAGT+ AT A G A+ PP + D++
Sbjct: 561 GMAP-----PPAPATASASAGTTNTAT------TAGPAPGGPAQPPPTPQPSMADLQFSQ 609
Query: 245 ELG 247
LG
Sbjct: 610 LLG 612
Score = 33.5 bits (75), Expect = 0.34
Identities = 15/36 (41%), Positives = 18/36 (50%), Gaps = 3/36 (8%)
Query: 31 PTPQPPTGPPPRLPNGEPSPDPGGKGTPRNGSPPPG 66
P P PP PPP P + P P G+P G+ PG
Sbjct: 657 PPPPPPPPPPPPAPEQQTMPPP---GSPSGGAGSPG 689
Score = 32.0 bits (71), Expect = 1.00
Identities = 45/169 (26%), Positives = 56/169 (33%), Gaps = 54/169 (31%)
Query: 23 GSPGASDPPTPQPPTGPPPRLPNGEPSPDPGGKGTPRNGSPPPGAPSSRFRVVKLPHGLG 82
G+PG + PP P S G T P PG P+ P
Sbjct: 558 GTPGMAPPPAP------------ATASASAGTTNTATTAGPAPGGPAQ-------PPPTP 598
Query: 83 EPYRRGRWTCVDVYERDLEPHSFGGLLEGIRGASG-GAGGRSLDS-RLELASLGLGA--- 137
+P DL+ F LL + G +G GAGG + S + +A G+ A
Sbjct: 599 QPSMA-----------DLQ---FSQLLGNLLGPAGPGAGGSGVASPTITVAMPGVPAFLQ 644
Query: 138 ---------------PTPPSGLSQGPTSWLRPPPTSPGPQARSFTGGLG 171
P PP P PPP SP A S GGLG
Sbjct: 645 GMTDFLQATQTAPPPPPPPPPPPPAPEQQTMPPPGSPSGGAGS-PGGLG 692
Score = 30.8 bits (68), Expect = 2.2
Identities = 15/35 (42%), Positives = 18/35 (51%), Gaps = 1/35 (2%)
Query: 22 PGSPGASDPPTPQPPTGPPPRLPNGEPSPDPGGKG 56
P P PP P+ T PPP P+G + PGG G
Sbjct: 659 PPPPPPPPPPAPEQQTMPPPGSPSG-GAGSPGGLG 692
Score = 30.4 bits (67), Expect = 2.9
Identities = 34/129 (26%), Positives = 48/129 (37%), Gaps = 35/129 (27%)
Query: 12 ITSVTTDYEGPGSP----GASD----PPTPQPPTGPPPRLPNGEPSPDPGGKGTPRNGSP 63
+ S T PG P G +D T PP PPP P P+P+ + P
Sbjct: 627 VASPTITVAMPGVPAFLQGMTDFLQATQTAPPPPPPPPPPP---PAPE-------QQTMP 676
Query: 64 PPGAPSSRFRVVKLPHGLGEPYRRGRWTCVDVYERDLEPHSFGGLLEGIRGASGGAGGRS 123
PPG+PS G G P G L P F +++G+ + G+ G
Sbjct: 677 PPGSPSG---------GAGSPGGLGL--------ESLSPEFFTSVVQGVLSSLLGSLGAR 719
Query: 124 LDSRLELAS 132
S +A+
Sbjct: 720 AGSSESIAA 728
>gi|5032069 splicing factor 3b, subunit 4 [Homo sapiens]
Length = 424
Score = 50.8 bits (120), Expect = 2e-06
Identities = 59/219 (26%), Positives = 74/219 (33%), Gaps = 36/219 (16%)
Query: 12 ITSVTTDYEGPGSP--GASDPPTPQP---PTGPPPRLPNGEPSPDPGGKGTPRNGSPPPG 66
++S+ + PG P G+ PP P P P G PP +P P G G P G+P G
Sbjct: 225 VSSLGSGLPPPGMPPPGSFPPPVPPPGALPPGIPPAMPPPPMPPGAAGHGPPSAGTPGAG 284
Query: 67 APSSRFRVVKLPHGLGEPYRRGRWTCVDVYERDLE---PHSFGGLLEGIRGASGGAGGRS 123
P H P+ G + + L PH G G G+ G R
Sbjct: 285 HPGH-------GHSHPHPFPPGGMPHPGMSQMQLAHHGPHGLGHPHAGPPGSGGQPPPRP 337
Query: 124 LDSRLELASLGLGAPT--PPSGLSQG------PTSWLRPPPTSPGPQARSFTGGLGQLVV 175
+G P PP G G P PPP P +TG
Sbjct: 338 PPGMPHPGPPPMGMPPRGPPFGSPMGHPGPMPPHGMRGPPPLMP---PHGYTGP----PR 390
Query: 176 PSKAKAEKPPLSASSPQQRPPEPETGESAGTSRAATPLP 214
P ++ PL P RPP P G G PLP
Sbjct: 391 PPPYGYQRGPLPPPRPTPRPPVPPRGPLRG------PLP 423
>gi|18079216 CASK interacting protein 1 [Homo sapiens]
Length = 1431
Score = 50.1 bits (118), Expect = 4e-06
Identities = 59/209 (28%), Positives = 81/209 (38%), Gaps = 44/209 (21%)
Query: 22 PGSPGASDP--PTPQPPTGPPPR-LPNGEPSPDPGGKGTPRNGSPPP------------- 65
P S A P P P PP PPP L + P P P +G R + PP
Sbjct: 1181 PASEQAGPPELPPPPPPAEPPPTDLAHLPPLPPP--EGEARKPAKPPVSPKPVLTQPVPK 1238
Query: 66 --GAPSSRFRVVKLPHGLGEP-YRRGRWTCVDVYERDLEPHSFGGLLEGIRGASGGAGGR 122
G+P+ + V LP G G P +R T V + P + ++ + G G+ G
Sbjct: 1239 LQGSPTPTSKKVPLP-GPGSPEVKRAHGTPPPVSPKPPPPPTAPKPVKAVAGLPSGSAG- 1296
Query: 123 SLDSRLELASLGLGAPTP-PSGLSQGPTSWLRPPPTSP---GPQARSFTGGLGQLVVPSK 178
P+P PS Q P + +PP T P A+ + G L VP
Sbjct: 1297 ---------------PSPAPSPARQPPAALAKPPGTPPSLGASPAKPPSPGAPALHVP-- 1339
Query: 179 AKAEKPPLSASSPQQRPPEPETGESAGTS 207
AK + +A++ PP P G S G S
Sbjct: 1340 AKPPRAAAAAAAAAAAPPAPPEGASPGDS 1368
Score = 39.3 bits (90), Expect = 0.006
Identities = 39/138 (28%), Positives = 50/138 (36%), Gaps = 22/138 (15%)
Query: 140 PPSGLSQGPTSWLRPPPTSPGPQARSFTGGLGQLVVPSKAKAEKPPLSASSPQQRPPEPE 199
PP G ++ P PP SP P VP K + P S P P PE
Sbjct: 1213 PPEGEARKPAK----PPVSPKPVLTQ--------PVP-KLQGSPTPTSKKVPLPGPGSPE 1259
Query: 200 TGESAGTSRAATPLPS------LRVEAEAG---GSGARTPPLSRRKAVDMRLRMELGAPE 250
+ GT +P P V+A AG GS +P S + L G P
Sbjct: 1260 VKRAHGTPPPVSPKPPPPPTAPKPVKAVAGLPSGSAGPSPAPSPARQPPAALAKPPGTPP 1319
Query: 251 EMGQVPPLDSRPSSPALY 268
+G P P +PAL+
Sbjct: 1320 SLGASPAKPPSPGAPALH 1337
Score = 35.8 bits (81), Expect = 0.069
Identities = 20/57 (35%), Positives = 21/57 (36%)
Query: 13 TSVTTDYEGPGSPGASDPPTPQPPTGPPPRLPNGEPSPDPGGKGTPRNGSPPPGAPS 69
TS GPGSP PP P P P P P G P + P APS
Sbjct: 1246 TSKKVPLPGPGSPEVKRAHGTPPPVSPKPPPPPTAPKPVKAVAGLPSGSAGPSPAPS 1302
Score = 32.7 bits (73), Expect = 0.59
Identities = 74/320 (23%), Positives = 109/320 (34%), Gaps = 65/320 (20%)
Query: 6 KKSSFQITSVTTDYEGPGSPGASDPPTPQPPTGPPPRLPNGEPSPDPGGKGTPRN----- 60
K ++FQ + ++ + + + A PT + P+ P P D G R+
Sbjct: 648 KMTTFQDSELSDELQAAMTGPAEVGPTTEKPSSHLPPTPRATTRQDSSLGGRARHMSSSQ 707
Query: 61 -----GSPPPGAPSSRFRVVKLPHGL--GEPYRRGRWTCVDVYERDLEPHSFGGLLEGIR 113
G P P +P SR + L G G P R R
Sbjct: 708 ELLGDGPPGPSSPMSRSQEYLLDEGPAPGTPPREAR------------------------ 743
Query: 114 GASGGAGGRSLDSRLELASLGLGAPTPPSGLSQGPTSWLRPP--PTSPGPQARSFTGGLG 171
G G S+ + AS+ P L G TS PP PT P + GG
Sbjct: 744 ---PGRHGHSI----KRASVPPVPGKPRQVLPPG-TSHFTPPQTPTKTRPGSPQALGG-P 794
Query: 172 QLVVPSKAKAEKPPLSASSPQQRPPEPETGESAGTSRAATPLPSLRVEAEAG--GSGART 229
P+ AK KP P +RP P + + T R + VE E G G
Sbjct: 795 HGPAPATAKV-KPTPQLLPPTERPMSPRSLPQSPTHRGFAYVLPQPVEGEVGPAAPGPAP 853
Query: 230 PPLSR---RKAVDMRLRMELGAPEE----MGQVPPLDSRPSSPALYFTHDASLVHKSPDP 282
PP+ + E G P++ + + DS P D LV + P
Sbjct: 854 PPVPTAVPTLCLPPEADAEPGRPKKRAHSLNRYAASDSEPE-------RDELLVPAAAGP 906
Query: 283 FGAVAAQKFSLAHSMLAISG 302
+ A ++ +HS+ A +G
Sbjct: 907 Y-ATVQRRVGRSHSVRAPAG 925
>gi|111118976 collagen, type II, alpha 1 isoform 1 precursor [Homo
sapiens]
Length = 1487
Score = 50.1 bits (118), Expect = 4e-06
Identities = 80/255 (31%), Positives = 90/255 (35%), Gaps = 45/255 (17%)
Query: 22 PGSPGASDPPTPQPPTGP-PPRLPNGEPSPDPGGKGTP-RNGSPPPGAPSSRFRVVKLPH 79
PG PG PP PQ TGP P+ GEP G KG G P P P P
Sbjct: 431 PGFPGPRGPPGPQGATGPLGPKGQTGEPG-IAGFKGEQGPKGEPGPAGPQG------APG 483
Query: 80 GLGEPYRRGRWTCVDVYERDLEPHSFGGLLEGIRGASGGAGGRSLDSRLELAS-LGLGAP 138
GE +RG EP G + G G G G R + LA G
Sbjct: 484 PAGEEGKRGARG---------EPGGVGPI--GPPGERGAPGNRGFPGQDGLAGPKGAPGE 532
Query: 139 TPPSGLSQGPTSWLRPP--PTSPG-PQARSFTGGLGQL-----VVPSKAKAEKPPLSASS 190
PSGL+ GP P P PG P AR TG G V PS A E
Sbjct: 533 RGPSGLA-GPKGANGDPGRPGEPGLPGARGLTGRPGDAGPQGKVGPSGAPGEDGRPGPPG 591
Query: 191 PQQRPPEP----------ETGESAGTSRAATP-LPSLR-VEAEAGGSGARTPPLSRRKAV 238
PQ +P GE P P LR + + G +GA PP A
Sbjct: 592 PQGARGQPGVMGFPGPKGANGEPGKAGEKGLPGAPGLRGLPGKDGETGAAGPPGPAGPAG 651
Query: 239 DMRLRMELGAPEEMG 253
+ R E GAP G
Sbjct: 652 E---RGEQGAPGPSG 663
Score = 42.4 bits (98), Expect = 7e-04
Identities = 61/219 (27%), Positives = 79/219 (36%), Gaps = 37/219 (16%)
Query: 22 PGSPGASDPPTPQPPTGPPPRLPNGEPSPD-PGGKGTPRNGSPPPGAPSSRFRVVKLPHG 80
PG PG S P P+ P GPP G+P D GK PPG +R P
Sbjct: 230 PGEPGVSGPMGPRGPPGPP-----GKPGDDGEAGKPGKAGERGPPGPQGAR----GFPGT 280
Query: 81 LGEPYRRGRWTCVDVYERDLEPHSFGGL--------LEGIRGASGGAGGRSLDSRLELAS 132
G P +G + GL G++G SG G +
Sbjct: 281 PGLPGVKGH-------------RGYPGLDGAKGEAGAPGVKGESGSPGENGSPGPMGPRG 327
Query: 133 L-GLGAPTPPSGLSQGPTSWLRPPPTSPGPQARSFTGGLGQLVVPSKAKAEKPPLSASSP 191
L G T P+G + + +P P P P GG G P AK E P A P
Sbjct: 328 LPGERGRTGPAGAAGARGNDGQPGPAGP-PGPVGPAGGPGFPGAPG-AKGEAGPTGARGP 385
Query: 192 Q--QRP-PEPETGESAGTSRAATPLPSLRVEAEAGGSGA 227
+ Q P EP T S G + A+ + + G +GA
Sbjct: 386 EGAQGPRGEPGTPGSPGPAGASGNPGTDGIPGAKGSAGA 424
Score = 40.0 bits (92), Expect = 0.004
Identities = 60/220 (27%), Positives = 73/220 (33%), Gaps = 45/220 (20%)
Query: 23 GSPGASDPPTPQPPTGPPPRLPNGEPSPDPGGKGTPRNGSPP--PGAPSSRFRVVKLPHG 80
GSPGA Q P G P P G G P PP G P R G
Sbjct: 708 GSPGAQGL---QGPRGLPGTPGTDGPKGASGPAGPPGAQGPPGLQGMPGERGAA-----G 759
Query: 81 LGEPY-RRGRWTCVDVYERDLEPHSFGGLLEGIRGASGGAGGRSLDSRLELASLGLGAPT 139
+ P RG DV E+ G GA G GGR L + P
Sbjct: 760 IAGPKGDRG-----DVGEK------------GPEGAPGKDGGRGLTGPI--------GPP 794
Query: 140 PPSGLSQGPTSWLRPPPTSPGPQARSFTGGLGQLVVPSKAKAEKPPLSASSPQQRPPEPE 199
P+G + G + PP + AR G G+ P A PP + P + + E
Sbjct: 795 GPAG-ANGEKGEVGPPGPAGSAGARGAPGERGETGPPGPAGFAGPPGADGQPGAKGEQGE 853
Query: 200 TGESA--------GTSRAATPLPSLRVEAEAGGSGARTPP 231
G+ G S A P V G GA+ PP
Sbjct: 854 AGQKGDAGAPGPQGPSGAPGPQGPTGVTGPKGARGAQGPP 893
Score = 39.7 bits (91), Expect = 0.005
Identities = 68/244 (27%), Positives = 84/244 (34%), Gaps = 37/244 (15%)
Query: 18 DYEGPGSPGASDPPTPQPPTG-PPPRLPNGEPSPDPGGKGTP----------RNGSP-PP 65
D PG G S P PQ PTG P+ G P PG G P NG+P PP
Sbjct: 859 DAGAPGPQGPSGAPGPQGPTGVTGPKGARGAQGP-PGATGFPGAAGRVGPPGSNGNPGPP 917
Query: 66 GAPSSRFRVVKL--------PHGLGEPYRRGRWTCVDVYERDLEPHSFG-GLLEGIRGAS 116
G P + P GEP +G EP G EG G
Sbjct: 918 GPPGPSGKDGPKGARGDSGPPGRAGEPGLQGP---AGPPGEKGEPGDDGPSGAEGPPGPQ 974
Query: 117 GGAGGRSL----DSRLELASLGLGAPTPPSGLSQGP-TSWLRPPPTSPGPQARSFTGGLG 171
G AG R + R E GL P+ G P S R PP GP TG G
Sbjct: 975 GLAGQRGIVGLPGQRGERGFPGLPGPSGEPGKQGAPGASGDRGPPGPVGPP--GLTGPAG 1032
Query: 172 QLVVPSKAKAEKPPLSASSPQQRPPEPETGE-----SAGTSRAATPLPSLRVEAEAGGSG 226
+ A+ PP + + ETG + G + P + + G +G
Sbjct: 1033 EPGREGSPGADGPPGRDGAAGVKGDRGETGAVGAPGAPGPPGSPGPAGPTGKQGDRGEAG 1092
Query: 227 ARTP 230
A+ P
Sbjct: 1093 AQGP 1096
Score = 39.3 bits (90), Expect = 0.006
Identities = 76/292 (26%), Positives = 95/292 (32%), Gaps = 68/292 (23%)
Query: 20 EGP-GSPGASDPPTPQPPTGPP-PRLPNGE--------PSPDPGGKGTP--RNGSPPPGA 67
+GP G+PG P GPP P NGE P+ G +G P R + PPG
Sbjct: 773 KGPEGAPGKDGGRGLTGPIGPPGPAGANGEKGEVGPPGPAGSAGARGAPGERGETGPPG- 831
Query: 68 PSSRFRVVKLPHGLGEPYRRGRWTCVDVYERDLEPHSFGGLLEGIRGASGGAGGRSLDSR 127
P G P P + G G +G G AG
Sbjct: 832 ----------PAGFAGP-----------------PGADG--QPGAKGEQGEAG------- 855
Query: 128 LELASLGLGAPTPPSGL--SQGPTSWLRPPPTSPG---PQARSFTGGLGQLVVPSKAKAE 182
+ G P PSG QGPT P P A F G G++ P
Sbjct: 856 -QKGDAGAPGPQGPSGAPGPQGPTGVTGPKGARGAQGPPGATGFPGAAGRVGPPGSNGNP 914
Query: 183 KPPLSASSPQQRPPEPETGESAGTSRAATP-------LPSLRVE-AEAGGSGARTPPLSR 234
PP + P+ G+S RA P P + E + G SGA PP +
Sbjct: 915 GPPGPPGPSGKDGPKGARGDSGPPGRAGEPGLQGPAGPPGEKGEPGDDGPSGAEGPPGPQ 974
Query: 235 RKAVDMRLRMELGAPEEMGQ--VPPLDSRPSSPALYFTHDASLVHKSPDPFG 284
A R +G P + G+ P L P AS P P G
Sbjct: 975 GLAGQ---RGIVGLPGQRGERGFPGLPGPSGEPGKQGAPGASGDRGPPGPVG 1023
Score = 38.9 bits (89), Expect = 0.008
Identities = 55/220 (25%), Positives = 66/220 (30%), Gaps = 45/220 (20%)
Query: 23 GSPGASDPPTPQPPTGPPPRLPNGEPSPDPGGKGTPRNGSPPPGAPSSRFRVVKLPHGLG 82
GSPG + P P P G P P+ G +G +G P P P P G
Sbjct: 312 GSPGENGSPGPMGPRGLPGERGRTGPAGAAGARGN--DGQPGPAGPPGPVGPAGGPGFPG 369
Query: 83 EPYRRGRWTCVDVYERDLEPHSFGGLLEGIRGASGGAGGRSLDSRLELASLGLGAPTPPS 142
P +G + P G RG G G R G P P
Sbjct: 370 APGAKG----------EAGP-------TGARGPEGAQGPR-------------GEPGTPG 399
Query: 143 GLSQGPTSWLRPPPTSPGPQARSFTGGLGQLVVPSKAKAEKPPLSASSPQQRPPEPETGE 202
S GP P T P A+ G G P PP + P+ +TGE
Sbjct: 400 --SPGPAGASGNPGTDGIPGAKGSAGAPGIAGAPGFPGPRGPPGPQGATGPLGPKGQTGE 457
Query: 203 SA-----------GTSRAATPLPSLRVEAEAGGSGARTPP 231
G A P + E G GAR P
Sbjct: 458 PGIAGFKGEQGPKGEPGPAGPQGAPGPAGEEGKRGARGEP 497
Score = 36.6 bits (83), Expect = 0.041
Identities = 51/181 (28%), Positives = 57/181 (31%), Gaps = 46/181 (25%)
Query: 21 GPGSPGASDPPTPQPPTGPPPRLPNGEPSPDPGGKGTPRNGSPPPGAPSSRFRVVKLPHG 80
GPG PGA PTG R P G P G GTP GSP P S
Sbjct: 364 GPGFPGAPGAKGEAGPTG--ARGPEGAQGP-RGEPGTP--GSPGPAGAS----------- 407
Query: 81 LGEPYRRGRWTCVDVYERDLEPHSFGGLLEGIRGASGGAGGRSLDSRLELASLGLGAPTP 140
G P +GI GA G AG + + G P
Sbjct: 408 -GNPG-----------------------TDGIPGAKGSAGAPGI-----AGAPGFPGPRG 438
Query: 141 PSGLSQGPTSWLRPPPTSPGPQARSFTGGLGQLVVPSKAKAEKPPLSASSPQQRPPEPET 200
P G QG T L P + P F G G P A + P A +R E
Sbjct: 439 PPG-PQGATGPLGPKGQTGEPGIAGFKGEQGPKGEPGPAGPQGAPGPAGEEGKRGARGEP 497
Query: 201 G 201
G
Sbjct: 498 G 498
Score = 35.8 bits (81), Expect = 0.069
Identities = 75/260 (28%), Positives = 92/260 (35%), Gaps = 56/260 (21%)
Query: 23 GSPGASDPPTP---------QPPTGPPPRLPNGE-----PSPDPGGKGTPRNGSP----- 63
G+PG PP P + +GPP R GE P+ PG KG P + P
Sbjct: 912 GNPGPPGPPGPSGKDGPKGARGDSGPPGRA--GEPGLQGPAGPPGEKGEPGDDGPSGAEG 969
Query: 64 PP------------GAPSSRFR--VVKLPHGLGEPYRRG-------RWTCVDVYERDLEP 102
PP G P R LP GEP ++G R V L
Sbjct: 970 PPGPQGLAGQRGIVGLPGQRGERGFPGLPGPSGEPGKQGAPGASGDRGPPGPVGPPGLTG 1029
Query: 103 HSFGGLLEGIRGASG-----GAGGRSLDSRLELASLGL-GAPTPP-SGLSQGPTSWL--R 153
+ EG GA G GA G D R E ++G GAP PP S GPT R
Sbjct: 1030 PAGEPGREGSPGADGPPGRDGAAGVKGD-RGETGAVGAPGAPGPPGSPGPAGPTGKQGDR 1088
Query: 154 PPPTSPGPQARSFTGGLGQLVVPSKAKAEKPPLSASSPQQRPPEPETGESAGTSRAATPL 213
+ GP S G + P + +K A P +R + G + P
Sbjct: 1089 GEAGAQGPMGPSGPAGARGIQGPQGPRGDKG--EAGEPGERGLKGHRGFTGLQGLPGPPG 1146
Query: 214 PS--LRVEAEAGGSGARTPP 231
PS AG SG R PP
Sbjct: 1147 PSGDQGASGPAGPSGPRGPP 1166
Score = 35.4 bits (80), Expect = 0.090
Identities = 71/267 (26%), Positives = 94/267 (35%), Gaps = 88/267 (32%)
Query: 26 GASDPPTPQPPTGPP-PRLPNGEP----SPDPGGK----GTPRNGSP--PPGAPSSRFRV 74
G PP PQ P G PR G+ +P P G+ GTP N P PPG P
Sbjct: 117 GPKGPPGPQGPAGEQGPRGDRGDKGEKGAPGPRGRDGEPGTPGNPGPPGPPGPPG----- 171
Query: 75 VKLPHGLGEPYRRGRWTCVDVYERDLEPHSFGGLLEGIRGASGGAGGRSLDSRLELASLG 134
P GLG + A+ AGG D + A LG
Sbjct: 172 ---PPGLGGNF-----------------------------AAQMAGG--FDEKAGGAQLG 197
Query: 135 -LGAPTPPSGLSQGPTSWLRPPPTSPGPQARSFTGGLGQLVVPSKAKAEKPPLSASSPQQ 193
+ P P G +GP P +PGPQ F G G+ P + P+ P
Sbjct: 198 VMQGPMGPMG-PRGPPG----PAGAPGPQ--GFQGNPGEPGEPGVS----GPMGPRGPPG 246
Query: 194 RPPEP-ETGESAGTSRAATPLPSLRVEAEAGGSGAR----TPPL--------------SR 234
P +P + GE+ +A P G GAR TP L ++
Sbjct: 247 PPGKPGDDGEAGKPGKAGERGP-------PGPQGARGFPGTPGLPGVKGHRGYPGLDGAK 299
Query: 235 RKAVDMRLRMELGAPEEMGQVPPLDSR 261
+A ++ E G+P E G P+ R
Sbjct: 300 GEAGAPGVKGESGSPGENGSPGPMGPR 326
Score = 33.9 bits (76), Expect = 0.26
Identities = 22/54 (40%), Positives = 24/54 (44%), Gaps = 2/54 (3%)
Query: 21 GP-GSPGASDPPTPQPPTGPPPRLPNGEPSPDPGGKGTPRNGSPP-PGAPSSRF 72
GP G GA+ P P P GP R P+ PG G P PP PG S F
Sbjct: 1170 GPSGKDGANGIPGPIGPPGPRGRSGETGPAGPPGNPGPPGPPGPPGPGIDMSAF 1223
Score = 32.7 bits (73), Expect = 0.59
Identities = 24/60 (40%), Positives = 26/60 (43%), Gaps = 12/60 (20%)
Query: 21 GP-GSPGASDPPTPQPPTGPPPRL-------PNGEPSP--DPGGKGTPRNGSP--PPGAP 68
GP G GAS P P P GPP + NG P P PG +G P PPG P
Sbjct: 1146 GPSGDQGASGPAGPSGPRGPPGPVGPSGKDGANGIPGPIGPPGPRGRSGETGPAGPPGNP 1205
Score = 32.3 bits (72), Expect = 0.76
Identities = 66/259 (25%), Positives = 76/259 (29%), Gaps = 78/259 (30%)
Query: 22 PGSPGASDPPTPQPPTGPP-------------------------------PRLPNGEPSP 50
PG+PG PP P P GPP P P G P P
Sbjct: 155 PGTPGNPGPPGPPGPPGPPGLGGNFAAQMAGGFDEKAGGAQLGVMQGPMGPMGPRGPPGP 214
Query: 51 -----------DPGGKGTPRNGSP-----PPGAPSSRFRVVKLPHGLGEPYRRGRWTCVD 94
+PG G P P PPG P P GE + G+
Sbjct: 215 AGAPGPQGFQGNPGEPGEPGVSGPMGPRGPPGPPGK-------PGDDGEAGKPGK----- 262
Query: 95 VYERDLE-PHSFGGL--LEGIRGASGGAGGRSLDSRLELASLGLGAPTPPSGLSQGPTSW 151
ER P G G+ G G G LD A GAP G S P
Sbjct: 263 AGERGPPGPQGARGFPGTPGLPGVKGHRGYPGLDG----AKGEAGAP-GVKGESGSPGEN 317
Query: 152 LRPPPTSPGPQARSFTGGLGQLVVPSKAKAEKPPLSASSPQQRPPEPETGESAGTSRAAT 211
P P P R G G+ A A + P P G + G
Sbjct: 318 GSPGPMGP----RGLPGERGRTGPAGAAGARG---NDGQPGPAGPPGPVGPAGGPGFPGA 370
Query: 212 PLPSLRVEAEAGGSGARTP 230
P + EAG +GAR P
Sbjct: 371 P----GAKGEAGPTGARGP 385
Score = 29.6 bits (65), Expect = 5.0
Identities = 19/52 (36%), Positives = 24/52 (46%), Gaps = 2/52 (3%)
Query: 39 PPPRLPNGEPSPD-PGGKGTPRNGSPPPGAPSSRFRVVKLPHGLGEPYRRGR 89
P P P+G+ P G PR G P P PS + +P +G P RGR
Sbjct: 1142 PGPPGPSGDQGASGPAGPSGPR-GPPGPVGPSGKDGANGIPGPIGPPGPRGR 1192
>gi|111118974 collagen, type II, alpha 1 isoform 2 precursor [Homo
sapiens]
Length = 1418
Score = 50.1 bits (118), Expect = 4e-06
Identities = 80/255 (31%), Positives = 90/255 (35%), Gaps = 45/255 (17%)
Query: 22 PGSPGASDPPTPQPPTGP-PPRLPNGEPSPDPGGKGTP-RNGSPPPGAPSSRFRVVKLPH 79
PG PG PP PQ TGP P+ GEP G KG G P P P P
Sbjct: 362 PGFPGPRGPPGPQGATGPLGPKGQTGEPG-IAGFKGEQGPKGEPGPAGPQG------APG 414
Query: 80 GLGEPYRRGRWTCVDVYERDLEPHSFGGLLEGIRGASGGAGGRSLDSRLELAS-LGLGAP 138
GE +RG EP G + G G G G R + LA G
Sbjct: 415 PAGEEGKRGARG---------EPGGVGPI--GPPGERGAPGNRGFPGQDGLAGPKGAPGE 463
Query: 139 TPPSGLSQGPTSWLRPP--PTSPG-PQARSFTGGLGQL-----VVPSKAKAEKPPLSASS 190
PSGL+ GP P P PG P AR TG G V PS A E
Sbjct: 464 RGPSGLA-GPKGANGDPGRPGEPGLPGARGLTGRPGDAGPQGKVGPSGAPGEDGRPGPPG 522
Query: 191 PQQRPPEP----------ETGESAGTSRAATP-LPSLR-VEAEAGGSGARTPPLSRRKAV 238
PQ +P GE P P LR + + G +GA PP A
Sbjct: 523 PQGARGQPGVMGFPGPKGANGEPGKAGEKGLPGAPGLRGLPGKDGETGAAGPPGPAGPAG 582
Query: 239 DMRLRMELGAPEEMG 253
+ R E GAP G
Sbjct: 583 E---RGEQGAPGPSG 594
Score = 42.4 bits (98), Expect = 7e-04
Identities = 61/219 (27%), Positives = 79/219 (36%), Gaps = 37/219 (16%)
Query: 22 PGSPGASDPPTPQPPTGPPPRLPNGEPSPD-PGGKGTPRNGSPPPGAPSSRFRVVKLPHG 80
PG PG S P P+ P GPP G+P D GK PPG +R P
Sbjct: 161 PGEPGVSGPMGPRGPPGPP-----GKPGDDGEAGKPGKAGERGPPGPQGAR----GFPGT 211
Query: 81 LGEPYRRGRWTCVDVYERDLEPHSFGGL--------LEGIRGASGGAGGRSLDSRLELAS 132
G P +G + GL G++G SG G +
Sbjct: 212 PGLPGVKGH-------------RGYPGLDGAKGEAGAPGVKGESGSPGENGSPGPMGPRG 258
Query: 133 L-GLGAPTPPSGLSQGPTSWLRPPPTSPGPQARSFTGGLGQLVVPSKAKAEKPPLSASSP 191
L G T P+G + + +P P P P GG G P AK E P A P
Sbjct: 259 LPGERGRTGPAGAAGARGNDGQPGPAGP-PGPVGPAGGPGFPGAPG-AKGEAGPTGARGP 316
Query: 192 Q--QRP-PEPETGESAGTSRAATPLPSLRVEAEAGGSGA 227
+ Q P EP T S G + A+ + + G +GA
Sbjct: 317 EGAQGPRGEPGTPGSPGPAGASGNPGTDGIPGAKGSAGA 355
Score = 40.0 bits (92), Expect = 0.004
Identities = 60/220 (27%), Positives = 73/220 (33%), Gaps = 45/220 (20%)
Query: 23 GSPGASDPPTPQPPTGPPPRLPNGEPSPDPGGKGTPRNGSPP--PGAPSSRFRVVKLPHG 80
GSPGA Q P G P P G G P PP G P R G
Sbjct: 639 GSPGAQGL---QGPRGLPGTPGTDGPKGASGPAGPPGAQGPPGLQGMPGERGAA-----G 690
Query: 81 LGEPY-RRGRWTCVDVYERDLEPHSFGGLLEGIRGASGGAGGRSLDSRLELASLGLGAPT 139
+ P RG DV E+ G GA G GGR L + P
Sbjct: 691 IAGPKGDRG-----DVGEK------------GPEGAPGKDGGRGLTGPI--------GPP 725
Query: 140 PPSGLSQGPTSWLRPPPTSPGPQARSFTGGLGQLVVPSKAKAEKPPLSASSPQQRPPEPE 199
P+G + G + PP + AR G G+ P A PP + P + + E
Sbjct: 726 GPAG-ANGEKGEVGPPGPAGSAGARGAPGERGETGPPGPAGFAGPPGADGQPGAKGEQGE 784
Query: 200 TGESA--------GTSRAATPLPSLRVEAEAGGSGARTPP 231
G+ G S A P V G GA+ PP
Sbjct: 785 AGQKGDAGAPGPQGPSGAPGPQGPTGVTGPKGARGAQGPP 824
Score = 39.7 bits (91), Expect = 0.005
Identities = 68/244 (27%), Positives = 84/244 (34%), Gaps = 37/244 (15%)
Query: 18 DYEGPGSPGASDPPTPQPPTG-PPPRLPNGEPSPDPGGKGTP----------RNGSP-PP 65
D PG G S P PQ PTG P+ G P PG G P NG+P PP
Sbjct: 790 DAGAPGPQGPSGAPGPQGPTGVTGPKGARGAQGP-PGATGFPGAAGRVGPPGSNGNPGPP 848
Query: 66 GAPSSRFRVVKL--------PHGLGEPYRRGRWTCVDVYERDLEPHSFG-GLLEGIRGAS 116
G P + P GEP +G EP G EG G
Sbjct: 849 GPPGPSGKDGPKGARGDSGPPGRAGEPGLQGP---AGPPGEKGEPGDDGPSGAEGPPGPQ 905
Query: 117 GGAGGRSL----DSRLELASLGLGAPTPPSGLSQGP-TSWLRPPPTSPGPQARSFTGGLG 171
G AG R + R E GL P+ G P S R PP GP TG G
Sbjct: 906 GLAGQRGIVGLPGQRGERGFPGLPGPSGEPGKQGAPGASGDRGPPGPVGPP--GLTGPAG 963
Query: 172 QLVVPSKAKAEKPPLSASSPQQRPPEPETGE-----SAGTSRAATPLPSLRVEAEAGGSG 226
+ A+ PP + + ETG + G + P + + G +G
Sbjct: 964 EPGREGSPGADGPPGRDGAAGVKGDRGETGAVGAPGAPGPPGSPGPAGPTGKQGDRGEAG 1023
Query: 227 ARTP 230
A+ P
Sbjct: 1024 AQGP 1027
Score = 39.3 bits (90), Expect = 0.006
Identities = 76/292 (26%), Positives = 95/292 (32%), Gaps = 68/292 (23%)
Query: 20 EGP-GSPGASDPPTPQPPTGPP-PRLPNGE--------PSPDPGGKGTP--RNGSPPPGA 67
+GP G+PG P GPP P NGE P+ G +G P R + PPG
Sbjct: 704 KGPEGAPGKDGGRGLTGPIGPPGPAGANGEKGEVGPPGPAGSAGARGAPGERGETGPPG- 762
Query: 68 PSSRFRVVKLPHGLGEPYRRGRWTCVDVYERDLEPHSFGGLLEGIRGASGGAGGRSLDSR 127
P G P P + G G +G G AG
Sbjct: 763 ----------PAGFAGP-----------------PGADG--QPGAKGEQGEAG------- 786
Query: 128 LELASLGLGAPTPPSGL--SQGPTSWLRPPPTSPG---PQARSFTGGLGQLVVPSKAKAE 182
+ G P PSG QGPT P P A F G G++ P
Sbjct: 787 -QKGDAGAPGPQGPSGAPGPQGPTGVTGPKGARGAQGPPGATGFPGAAGRVGPPGSNGNP 845
Query: 183 KPPLSASSPQQRPPEPETGESAGTSRAATP-------LPSLRVE-AEAGGSGARTPPLSR 234
PP + P+ G+S RA P P + E + G SGA PP +
Sbjct: 846 GPPGPPGPSGKDGPKGARGDSGPPGRAGEPGLQGPAGPPGEKGEPGDDGPSGAEGPPGPQ 905
Query: 235 RKAVDMRLRMELGAPEEMGQ--VPPLDSRPSSPALYFTHDASLVHKSPDPFG 284
A R +G P + G+ P L P AS P P G
Sbjct: 906 GLAGQ---RGIVGLPGQRGERGFPGLPGPSGEPGKQGAPGASGDRGPPGPVG 954
Score = 38.9 bits (89), Expect = 0.008
Identities = 55/220 (25%), Positives = 66/220 (30%), Gaps = 45/220 (20%)
Query: 23 GSPGASDPPTPQPPTGPPPRLPNGEPSPDPGGKGTPRNGSPPPGAPSSRFRVVKLPHGLG 82
GSPG + P P P G P P+ G +G +G P P P P G
Sbjct: 243 GSPGENGSPGPMGPRGLPGERGRTGPAGAAGARGN--DGQPGPAGPPGPVGPAGGPGFPG 300
Query: 83 EPYRRGRWTCVDVYERDLEPHSFGGLLEGIRGASGGAGGRSLDSRLELASLGLGAPTPPS 142
P +G + P G RG G G R G P P
Sbjct: 301 APGAKG----------EAGP-------TGARGPEGAQGPR-------------GEPGTPG 330
Query: 143 GLSQGPTSWLRPPPTSPGPQARSFTGGLGQLVVPSKAKAEKPPLSASSPQQRPPEPETGE 202
S GP P T P A+ G G P PP + P+ +TGE
Sbjct: 331 --SPGPAGASGNPGTDGIPGAKGSAGAPGIAGAPGFPGPRGPPGPQGATGPLGPKGQTGE 388
Query: 203 SA-----------GTSRAATPLPSLRVEAEAGGSGARTPP 231
G A P + E G GAR P
Sbjct: 389 PGIAGFKGEQGPKGEPGPAGPQGAPGPAGEEGKRGARGEP 428
Score = 36.6 bits (83), Expect = 0.041
Identities = 51/181 (28%), Positives = 57/181 (31%), Gaps = 46/181 (25%)
Query: 21 GPGSPGASDPPTPQPPTGPPPRLPNGEPSPDPGGKGTPRNGSPPPGAPSSRFRVVKLPHG 80
GPG PGA PTG R P G P G GTP GSP P S
Sbjct: 295 GPGFPGAPGAKGEAGPTG--ARGPEGAQGP-RGEPGTP--GSPGPAGAS----------- 338
Query: 81 LGEPYRRGRWTCVDVYERDLEPHSFGGLLEGIRGASGGAGGRSLDSRLELASLGLGAPTP 140
G P +GI GA G AG + + G P
Sbjct: 339 -GNPG-----------------------TDGIPGAKGSAGAPGI-----AGAPGFPGPRG 369
Query: 141 PSGLSQGPTSWLRPPPTSPGPQARSFTGGLGQLVVPSKAKAEKPPLSASSPQQRPPEPET 200
P G QG T L P + P F G G P A + P A +R E
Sbjct: 370 PPG-PQGATGPLGPKGQTGEPGIAGFKGEQGPKGEPGPAGPQGAPGPAGEEGKRGARGEP 428
Query: 201 G 201
G
Sbjct: 429 G 429
Score = 35.8 bits (81), Expect = 0.069
Identities = 75/260 (28%), Positives = 92/260 (35%), Gaps = 56/260 (21%)
Query: 23 GSPGASDPPTP---------QPPTGPPPRLPNGE-----PSPDPGGKGTPRNGSP----- 63
G+PG PP P + +GPP R GE P+ PG KG P + P
Sbjct: 843 GNPGPPGPPGPSGKDGPKGARGDSGPPGRA--GEPGLQGPAGPPGEKGEPGDDGPSGAEG 900
Query: 64 PP------------GAPSSRFR--VVKLPHGLGEPYRRG-------RWTCVDVYERDLEP 102
PP G P R LP GEP ++G R V L
Sbjct: 901 PPGPQGLAGQRGIVGLPGQRGERGFPGLPGPSGEPGKQGAPGASGDRGPPGPVGPPGLTG 960
Query: 103 HSFGGLLEGIRGASG-----GAGGRSLDSRLELASLGL-GAPTPP-SGLSQGPTSWL--R 153
+ EG GA G GA G D R E ++G GAP PP S GPT R
Sbjct: 961 PAGEPGREGSPGADGPPGRDGAAGVKGD-RGETGAVGAPGAPGPPGSPGPAGPTGKQGDR 1019
Query: 154 PPPTSPGPQARSFTGGLGQLVVPSKAKAEKPPLSASSPQQRPPEPETGESAGTSRAATPL 213
+ GP S G + P + +K A P +R + G + P
Sbjct: 1020 GEAGAQGPMGPSGPAGARGIQGPQGPRGDKG--EAGEPGERGLKGHRGFTGLQGLPGPPG 1077
Query: 214 PS--LRVEAEAGGSGARTPP 231
PS AG SG R PP
Sbjct: 1078 PSGDQGASGPAGPSGPRGPP 1097
Score = 35.4 bits (80), Expect = 0.090
Identities = 71/267 (26%), Positives = 94/267 (35%), Gaps = 88/267 (32%)
Query: 26 GASDPPTPQPPTGPP-PRLPNGEP----SPDPGGK----GTPRNGSP--PPGAPSSRFRV 74
G PP PQ P G PR G+ +P P G+ GTP N P PPG P
Sbjct: 48 GPKGPPGPQGPAGEQGPRGDRGDKGEKGAPGPRGRDGEPGTPGNPGPPGPPGPPG----- 102
Query: 75 VKLPHGLGEPYRRGRWTCVDVYERDLEPHSFGGLLEGIRGASGGAGGRSLDSRLELASLG 134
P GLG + A+ AGG D + A LG
Sbjct: 103 ---PPGLGGNF-----------------------------AAQMAGG--FDEKAGGAQLG 128
Query: 135 -LGAPTPPSGLSQGPTSWLRPPPTSPGPQARSFTGGLGQLVVPSKAKAEKPPLSASSPQQ 193
+ P P G +GP P +PGPQ F G G+ P + P+ P
Sbjct: 129 VMQGPMGPMG-PRGPPG----PAGAPGPQ--GFQGNPGEPGEPGVS----GPMGPRGPPG 177
Query: 194 RPPEP-ETGESAGTSRAATPLPSLRVEAEAGGSGAR----TPPL--------------SR 234
P +P + GE+ +A P G GAR TP L ++
Sbjct: 178 PPGKPGDDGEAGKPGKAGERGP-------PGPQGARGFPGTPGLPGVKGHRGYPGLDGAK 230
Query: 235 RKAVDMRLRMELGAPEEMGQVPPLDSR 261
+A ++ E G+P E G P+ R
Sbjct: 231 GEAGAPGVKGESGSPGENGSPGPMGPR 257
Score = 33.9 bits (76), Expect = 0.26
Identities = 22/54 (40%), Positives = 24/54 (44%), Gaps = 2/54 (3%)
Query: 21 GP-GSPGASDPPTPQPPTGPPPRLPNGEPSPDPGGKGTPRNGSPP-PGAPSSRF 72
GP G GA+ P P P GP R P+ PG G P PP PG S F
Sbjct: 1101 GPSGKDGANGIPGPIGPPGPRGRSGETGPAGPPGNPGPPGPPGPPGPGIDMSAF 1154
Score = 32.7 bits (73), Expect = 0.59
Identities = 24/60 (40%), Positives = 26/60 (43%), Gaps = 12/60 (20%)
Query: 21 GP-GSPGASDPPTPQPPTGPPPRL-------PNGEPSP--DPGGKGTPRNGSP--PPGAP 68
GP G GAS P P P GPP + NG P P PG +G P PPG P
Sbjct: 1077 GPSGDQGASGPAGPSGPRGPPGPVGPSGKDGANGIPGPIGPPGPRGRSGETGPAGPPGNP 1136
Score = 32.3 bits (72), Expect = 0.76
Identities = 66/259 (25%), Positives = 76/259 (29%), Gaps = 78/259 (30%)
Query: 22 PGSPGASDPPTPQPPTGPP-------------------------------PRLPNGEPSP 50
PG+PG PP P P GPP P P G P P
Sbjct: 86 PGTPGNPGPPGPPGPPGPPGLGGNFAAQMAGGFDEKAGGAQLGVMQGPMGPMGPRGPPGP 145
Query: 51 -----------DPGGKGTPRNGSP-----PPGAPSSRFRVVKLPHGLGEPYRRGRWTCVD 94
+PG G P P PPG P P GE + G+
Sbjct: 146 AGAPGPQGFQGNPGEPGEPGVSGPMGPRGPPGPPGK-------PGDDGEAGKPGK----- 193
Query: 95 VYERDLE-PHSFGGL--LEGIRGASGGAGGRSLDSRLELASLGLGAPTPPSGLSQGPTSW 151
ER P G G+ G G G LD A GAP G S P
Sbjct: 194 AGERGPPGPQGARGFPGTPGLPGVKGHRGYPGLDG----AKGEAGAP-GVKGESGSPGEN 248
Query: 152 LRPPPTSPGPQARSFTGGLGQLVVPSKAKAEKPPLSASSPQQRPPEPETGESAGTSRAAT 211
P P P R G G+ A A + P P G + G
Sbjct: 249 GSPGPMGP----RGLPGERGRTGPAGAAGARG---NDGQPGPAGPPGPVGPAGGPGFPGA 301
Query: 212 PLPSLRVEAEAGGSGARTP 230
P + EAG +GAR P
Sbjct: 302 P----GAKGEAGPTGARGP 316
Score = 29.6 bits (65), Expect = 5.0
Identities = 19/52 (36%), Positives = 24/52 (46%), Gaps = 2/52 (3%)
Query: 39 PPPRLPNGEPSPD-PGGKGTPRNGSPPPGAPSSRFRVVKLPHGLGEPYRRGR 89
P P P+G+ P G PR G P P PS + +P +G P RGR
Sbjct: 1073 PGPPGPSGDQGASGPAGPSGPR-GPPGPVGPSGKDGANGIPGPIGPPGPRGR 1123
>gi|32964830 collagen, type VIII, alpha 2 [Homo sapiens]
Length = 703
Score = 49.3 bits (116), Expect = 6e-06
Identities = 74/257 (28%), Positives = 87/257 (33%), Gaps = 41/257 (15%)
Query: 22 PGSPGASDPPTPQPPTGPPPRLPNGEPSP-------------DPGGKGTP-RNGSP-PPG 66
PG PGA P P G P P GEP P PG G P + G+P PPG
Sbjct: 172 PGKPGAQGVPGPPGFQGEPG--PQGEPGPPGDRGLKGDNGVGQPGLPGAPGQGGAPGPPG 229
Query: 67 APSSRFRVVKLPHGLGEPYRRGRWTCVDVYERDLEPHSFGGLLEGIRGASGGAGGRSLDS 126
P P GLG+P G P G G GA G G +D
Sbjct: 230 LPG--------PAGLGKPGLDGLPGAPGDKGESGPPGVPGP--RGEPGAVGPKGPPGVDG 279
Query: 127 RLELASLGLGAPTPPSGL-----SQGPTSWLRPP----PTSPGPQARSFTGGLGQLVVPS 177
+ GL P PSG ++GP + P P PGP+ G+ L+
Sbjct: 280 VGVPGAAGLPGPQGPSGAKGEPGTRGPPGLIGPTGYGMPGLPGPKGDRGPAGVPGLLGDR 339
Query: 178 KAKAEKPPLSASSPQQRPPEPETGESAG-TSRAATPLPSLRVEAEAGGSGARTPPLSRRK 236
E PQ P SAG R P P + EAG G P R
Sbjct: 340 GEPGEDGEPGEQGPQGLGGPPGLPGSAGLPGRRGPPGP----KGEAGPGGPPGVPGIRGD 395
Query: 237 AVDMRLRMELGAPEEMG 253
L + G P E G
Sbjct: 396 QGPSGLAGKPGVPGERG 412
Score = 38.9 bits (89), Expect = 0.008
Identities = 68/238 (28%), Positives = 80/238 (33%), Gaps = 36/238 (15%)
Query: 23 GSPGASDPPTPQPPTGPP--PRLP-------NGEPSPDPGGKGTPRNG-SPPPGAPSSRF 72
G PG P P+ P GPP P P +G+P P G G R G + PPG P +
Sbjct: 77 GEPGPPGKPGPRGPPGPPGFPGKPGMGKPGLHGQPGP-AGPPGFSRMGKAGPPGLP-GKV 134
Query: 73 RVVKLPHGLGEPYRRGRWTCVDVYERDLEPHSFGGLLEGIRGASG--------------G 118
P GEP RG P G + G GA G G
Sbjct: 135 GPPGQPGLRGEPGIRGDQGLRGPPGPPGLPGPSGITIPGKPGAQGVPGPPGFQGEPGPQG 194
Query: 119 AGGRSLDSRLELASLGLGAPTPPSGLSQGPTSWLRPPPTSPGPQARSFTGGLGQLVVPSK 178
G D L+ G+G P P QG PP PGP G G P
Sbjct: 195 EPGPPGDRGLK-GDNGVGQPGLPGAPGQGGAP---GPPGLPGPAGLGKPGLDGLPGAPGD 250
Query: 179 AKAEKPPLSASSPQQRP----PEPETGESAGTSRAATPLPSLRVEAEAGGS-GARTPP 231
K E P P+ P P+ G A LP + + A G G R PP
Sbjct: 251 -KGESGPPGVPGPRGEPGAVGPKGPPGVDGVGVPGAAGLPGPQGPSGAKGEPGTRGPP 307
Score = 38.9 bits (89), Expect = 0.008
Identities = 71/270 (26%), Positives = 85/270 (31%), Gaps = 81/270 (30%)
Query: 20 EGPGSPGASDPPTPQPPTGP--------PPRL-------------PNGEPSP-------- 50
+G G PGA+ P PQ P+G PP L P G+ P
Sbjct: 278 DGVGVPGAAGLPGPQGPSGAKGEPGTRGPPGLIGPTGYGMPGLPGPKGDRGPAGVPGLLG 337
Query: 51 ---DPGGKGTPRNGSP-----PPGAPSSRFRVVKLPHGLGEPYRRGRWTCVDVYERDLEP 102
+PG G P P PPG P S LP G P +G + P
Sbjct: 338 DRGEPGEDGEPGEQGPQGLGGPPGLPGS----AGLPGRRGPPGPKG----------EAGP 383
Query: 103 HSFGGL--LEGIRGASGGAGGRSLDSRLELASLGLGAPTPPSGLSQGPTSWLRPPPTSPG 160
G+ + G +G SG AG + L GA PP GPT P +
Sbjct: 384 GGPPGVPGIRGDQGPSGLAGKPGVPGERGLP----GAHGPP-----GPTGPKGEPGFTGR 434
Query: 161 PQARSFTGGLGQ-----------LVVPSKAKAEKPPLSASSPQQRP--------PEPETG 201
P G LGQ L PS + P PQ P P P
Sbjct: 435 PGGPGVAGALGQKGDLGLPGQPGLRGPSGIPGLQGPAGPIGPQGLPGLKGEPGLPGPPGE 494
Query: 202 ESAGTSRAATPLPSLRVEAEAGGSGARTPP 231
AG A P V G +G PP
Sbjct: 495 GRAGEPGTAGPTGPPGVPGSPGITGPPGPP 524
Score = 32.0 bits (71), Expect = 1.00
Identities = 12/19 (63%), Positives = 13/19 (68%)
Query: 22 PGSPGASDPPTPQPPTGPP 40
PGSPG + PP P P GPP
Sbjct: 512 PGSPGITGPPGPPGPPGPP 530
Score = 31.6 bits (70), Expect = 1.3
Identities = 21/52 (40%), Positives = 23/52 (44%), Gaps = 8/52 (15%)
Query: 21 GPGSPGASDPPTPQPPTGPPPRLPNGEPSPDPGGKGTPRNGSP--PPGAPSS 70
GP G + P PTGPP G P PG G P P PPGAP +
Sbjct: 490 GPPGEGRAGEPGTAGPTGPP-----GVPG-SPGITGPPGPPGPPGPPGAPGA 535
>gi|116256464 hypothetical protein LOC343990 [Homo sapiens]
Length = 962
Score = 49.3 bits (116), Expect = 6e-06
Identities = 75/277 (27%), Positives = 97/277 (35%), Gaps = 58/277 (20%)
Query: 13 TSVTTDYEGPGSPG---ASDPPTPQ---PPTGP-----PPRLPNGEPSPDP-GGKGTPRN 60
+++T E G PG +S P TP+ P + P PP P G P+P P GGK ++
Sbjct: 316 SALTASVEEGGVPGEDPSSRPATPELAEPESAPTLRVEPPSPPEGPPNPGPDGGK---QD 372
Query: 61 GSPPPGAP-----SSRFRVVKLPHGLGEPYRRGRWTCVDVYERDLEPHSFGGLLEGIRGA 115
G PP P VV P + P+ + E D P +
Sbjct: 373 GEAPPAGPCAPATDKAEEVVCAPEDVASPFPTA------IPEGDTTPPETDPAATSEAPS 426
Query: 116 SGGAGGRSLDSRLELASLGLGAPTPPSGLSQGPTSWLRPPPTSPGPQARSFT---GGLGQ 172
+ RS+ E PTPP P PP +P P+ + T G G
Sbjct: 427 ARDGPERSVPKEAE--------PTPP----VLPDEEKGPPGPAPEPEREAETEPERGAGT 474
Query: 173 L-----VVPSKAKAEKPPLSASSPQQRPPEPETGESAGTSRAATPLP-------SLRVEA 220
PS A A PP S + RP G +A AA P SL EA
Sbjct: 475 EPERIGTEPSTAPAPSPPAPKSCLKHRPAAASEGPAASPPLAAAESPPVEPGPGSLDAEA 534
Query: 221 EA----GGSGARTPPLSRRKAVDMRLRMELGAPEEMG 253
A A PP +A R + E G E G
Sbjct: 535 AAPERPKAERAEAPPAGAERAAPER-KAERGGAELRG 570
Score = 31.6 bits (70), Expect = 1.3
Identities = 34/113 (30%), Positives = 44/113 (38%), Gaps = 25/113 (22%)
Query: 176 PSKAKAEKPPLSASSPQQRPPE------PETGESAGTSRAATPLPSLRVEAEAGGSGART 229
P + + E+ PL SP++RP P+ G G PLP GG+ AR
Sbjct: 259 PEEEENEEKPLLEVSPEERPSSGQQDVAPDRGPEPG---PPAPLP------PPGGARARR 309
Query: 230 PPLSRRKAVDMRLRMELGAPEEMGQVPPLD--SRPSSPALYFTHDASLVHKSP 280
L A L A E G VP D SRP++P L A + P
Sbjct: 310 ARLQHSSA--------LTASVEEGGVPGEDPSSRPATPELAEPESAPTLRVEP 354
>gi|4502961 alpha 1 type VII collagen precursor [Homo sapiens]
Length = 2944
Score = 48.9 bits (115), Expect = 8e-06
Identities = 59/194 (30%), Positives = 72/194 (37%), Gaps = 20/194 (10%)
Query: 22 PGSPGASDPPTPQPPTGPPPRLPNGEPSPD--PGGKGTPRNGSPPPGAPSSRFRVVKLPH 79
PG+PG PP P+ P +GE P G KG P GS P V +
Sbjct: 2081 PGTPGPPGPPGPKVSVDEPGPGLSGEQGPPGLKGAKGEP--GSNGDQGPKGDRGVPGIKG 2138
Query: 80 GLGEPYRRGRWTCVDV-YERDLEPHSFGGLLEGIRGASGGAGGRSLDSRLELASLGLGAP 138
GEP RG+ + ER + L+G RG G GG + GL P
Sbjct: 2139 DRGEPGPRGQDGNPGLPGERGMAGPEGKPGLQGPRGPPGPVGGHGDPG--PPGAPGLAGP 2196
Query: 139 TPPSGLSQGPTSWLRPPPTSPGPQARSFTGGLGQLVVPSKAKAEKPPLSASSPQQRPPEP 198
P QGP S L+ P GP R TG G + +P P PQ P P
Sbjct: 2197 AGP----QGP-SGLKGEPGETGPPGRGLTGPTGAVGLP----GPPGPSGLVGPQGSPGLP 2247
Query: 199 ----ETGESAGTSR 208
ETG+ R
Sbjct: 2248 GQVGETGKPGAPGR 2261
Score = 46.6 bits (109), Expect = 4e-05
Identities = 65/209 (31%), Positives = 78/209 (37%), Gaps = 47/209 (22%)
Query: 20 EGPGSPGASDPPTPQPPTGPPPRLPNGEPSPDPGGKGTPRNGSPPPGAPSSRFRVVKLPH 79
EGPG PG P P P P PR P G DPG +G PPG P + + K
Sbjct: 1359 EGPGLPGRKGDPGPSGP--PGPRGPLG----DPGPRG-------PPGLPGTAMKGDKGDR 1405
Query: 80 GLGEPYRRGRWTCVDVYERDLEPHSFGGLLEGIRGASG--------GAGGRSLDSRLELA 131
G P G E + P G L G+ G+ G G G DS E
Sbjct: 1406 GERGPPGPG--------EGGIAPGEPG--LPGLPGSPGPQGPVGPPGKKGEKGDS--EDG 1453
Query: 132 SLGL-GAPTPPSGLSQGPTSWLRPPPTSPGPQA-RSFTGGLGQL------VVPSKAKAEK 183
+ GL G P P QGP R PP + GP+ R F G LG+ P A +
Sbjct: 1454 APGLPGQPGSPG--EQGP----RGPPGAIGPKGDRGFPGPLGEAGEKGERGPPGPAGSRG 1507
Query: 184 PPLSASSPQQRPPEPETGESAGTSRAATP 212
P A P + PE G + P
Sbjct: 1508 LPGVAGRPGAKGPEGPPGPTGRQGEKGEP 1536
Score = 45.4 bits (106), Expect = 9e-05
Identities = 65/222 (29%), Positives = 72/222 (32%), Gaps = 52/222 (23%)
Query: 22 PGSPGASDPPTPQPPTGPP----PRLPNGEPSPDPG------GKGTP-RNGSPPPGAPSS 70
PG+PG P P G P PR P GEP PG G G P R G P P P
Sbjct: 1319 PGAPGLKGSPGLPGPRGDPGERGPRGPKGEPGA-PGQVIGGEGPGLPGRKGDPGPSGPPG 1377
Query: 71 RFRVVKLPHG-LGEPYRRGRWTCVDVYERDLEPHSFGGLLEGIRGASGGAGGRSLDSRLE 129
P G LG+P RG P G ++G G G R
Sbjct: 1378 -------PRGPLGDPGPRG-------------PPGLPG--TAMKGDKGDRGER------- 1408
Query: 130 LASLGLGAPTPPSGLSQGPTSWLRPPPTSPGPQARSFTGGLGQLVVPSKAKAEKPPLSAS 189
G P P G L P SPGPQ G S+ A P
Sbjct: 1409 ------GPPGPGEGGIAPGEPGLPGLPGSPGPQGPVGPPGKKGEKGDSEDGAPGLPGQPG 1462
Query: 190 SPQQRPPEPETGESAGTSRAATPLPSLRVEAEAGGSGARTPP 231
SP ++ P G P P EAG G R PP
Sbjct: 1463 SPGEQGPRGPPGAIGPKGDRGFPGPL----GEAGEKGERGPP 1500
Score = 43.9 bits (102), Expect = 3e-04
Identities = 72/248 (29%), Positives = 88/248 (35%), Gaps = 34/248 (13%)
Query: 22 PGSPGASDPPTPQ-PPTGPPPRLPNGEPSPDPGGKGTP-RNGSP-PPGAPSSRFRVVKLP 78
PG PG + P PQ PP + G P D G G+P R G+P PGAP + LP
Sbjct: 1274 PGLPGRTGAPGPQGPPGSATAKGERGFPGAD-GRPGSPGRAGNPGTPGAPGLK-GSPGLP 1331
Query: 79 HGLGEPYRRGRWTCVDVYERDLEPHSFGGLLEGIRGASGGAGGRSLDSRLELASLGLGAP 138
G+P RG EP + G + I G G GR D G P
Sbjct: 1332 GPRGDPGERG------PRGPKGEPGAPG---QVIGGEGPGLPGRKGDP-------GPSGP 1375
Query: 139 TPPSGLSQGPTSWLRPPPTSPGPQARSFTGGLGQLVVP-------SKAKAEKPPLSASSP 191
P G P R PP PG + G G+ P + + P L S
Sbjct: 1376 PGPRGPLGDPGP--RGPPGLPGTAMKGDKGDRGERGPPGPGEGGIAPGEPGLPGLPGSPG 1433
Query: 192 QQRP--PEPETGESAGTSRAATPLPSLRVEAEAGGSGARTPPLSRRKAVDMRLRMELGAP 249
Q P P + GE + A LP G G R PP + D LG
Sbjct: 1434 PQGPVGPPGKKGEKGDSEDGAPGLPG--QPGSPGEQGPRGPPGAIGPKGDRGFPGPLGEA 1491
Query: 250 EEMGQVPP 257
E G+ P
Sbjct: 1492 GEKGERGP 1499
Score = 38.1 bits (87), Expect = 0.014
Identities = 72/268 (26%), Positives = 97/268 (36%), Gaps = 59/268 (22%)
Query: 22 PGSPGASDPPTPQPPTGPP----------------PRLPNGEPSP--DPGGKGTP-RNGS 62
PGSPG PP + G P PR G+P P + G G P R G
Sbjct: 2376 PGSPGPPGPPGVKGDLGLPGLPGAPGVVGFPGQTGPRGEMGQPGPSGERGLAGPPGREGI 2435
Query: 63 P----PPGAP-------SSRFRVVKLPHGLGEPYRRGRWTCVDVYERDLEPHSFGGLLEG 111
P PPG P +S + K G+G P RG + D P EG
Sbjct: 2436 PGPLGPPGPPGSVGPPGASGLKGDKGDPGVGLPGPRGERGEPGIRGEDGRPGQ-----EG 2490
Query: 112 IRGASGGAGGR-SLDSRLELASLGLGAPTPPSGLSQGPTSWLRPPPTSPGPQARSFTGGL 170
RG +G G R + ++ S GL S + GP PGP R G +
Sbjct: 2491 PRGLTGPPGSRGERGEKGDVGSAGLKGDKGDSAVILGP----------PGP--RGAKGDM 2538
Query: 171 GQLVVPSKAKAEKPPLSAS-SPQQRPPEPETGESAGTSRAATPLPSLR----VEAEAGGS 225
G+ P +K P + P + + E G+ + + LP LR + + G +
Sbjct: 2539 GER-GPRGLDGDKGPRGDNGDPGDKGSKGEPGD-----KGSAGLPGLRGLLGPQGQPGAA 2592
Query: 226 GARTPPLSRRKAVDMRLRMELGAPEEMG 253
G P S K +R E G MG
Sbjct: 2593 GIPGDPGSPGKDGVPGIRGEKGDVGFMG 2620
Score = 36.6 bits (83), Expect = 0.041
Identities = 62/222 (27%), Positives = 72/222 (32%), Gaps = 23/222 (10%)
Query: 22 PGSPGASDPPTPQPPTGPPPRL-PNGEPSPDPGGKGTP-RNGSPPPGAPSSRFRVVKLPH 79
PG PG P + P G R P G+ P PG KG P R G P P P R V
Sbjct: 1582 PGDPGPKGDPGDRGPIGLTGRAGPPGDSGP-PGEKGDPGRPGPPGPVGPRGRDGEVGEKG 1640
Query: 80 GLGEPYRRGRWTCVDVYERDLEPHSFGGLLEGIRGASGGAGGRSLDSRLELASLGLGAPT 139
G P G P G G+RGA G G + + + G
Sbjct: 1641 DEGPPGDPGL------------PGKAGE--RGLRGAPGVRG--PVGEKGDQGDPGEDGRN 1684
Query: 140 PPSGLSQGPTSWLRPPPTSPGPQARSFTGGLGQLVVPSKA-KAEKPPLSASSPQQRPPEP 198
G S GP R P PGP R G G + ++ P P P
Sbjct: 1685 GSPG-SSGPKG-DRGEPGPPGPPGRLVDTGPGAREKGEPGDRGQEGPRGPKGDPGLPGAP 1742
Query: 199 ETGESAGTSRAATPLPSLRVEAEAGGSGARTPP-LSRRKAVD 239
G P V AG G R PP L R +D
Sbjct: 1743 GERGIEGFRGPPGPQGDPGVRGPAGEKGDRGPPGLDGRSGLD 1784
Score = 35.4 bits (80), Expect = 0.090
Identities = 55/199 (27%), Positives = 66/199 (33%), Gaps = 44/199 (22%)
Query: 22 PGSPGASDPPTPQPPTGPPPRLPNGEP-SPDPGGKG----TPRNGSPPPGAPSSRF---R 73
PG+PG + P PQ P+G GEP P G+G T G P P PS
Sbjct: 2188 PGAPGLAGPAGPQGPSG-----LKGEPGETGPPGRGLTGPTGAVGLPGPPGPSGLVGPQG 2242
Query: 74 VVKLPHGLGEPYRRGRWTCVDVYERDLEPHSFGGLLEGIRGASGGAGGRSLDSRLELASL 133
LP +GE + G G GASG G R S S
Sbjct: 2243 SPGLPGQVGETGKPG--------------------APGRDGASGKDGDRG--SPGVPGSP 2280
Query: 134 GLGAPTPPSGLSQGPTSWLRPPPTSPGPQARSFTGGLGQLVVPSKAKAEKPPLSASSPQQ 193
GL P P G GPT +PG G G+ P + + +
Sbjct: 2281 GLPGPVGPKG-EPGPTG-------APGQAVVGLPGAKGEKGAPGGLAGDLVGEPGAKGDR 2332
Query: 194 RPPEPETGESAGTSRAATP 212
P P GE RA P
Sbjct: 2333 GLPGPR-GEKGEAGRAGEP 2350
Score = 35.0 bits (79), Expect = 0.12
Identities = 65/242 (26%), Positives = 82/242 (33%), Gaps = 43/242 (17%)
Query: 22 PGSPGASDPPTPQPPTGPP----PRLPNGE-PSPDPGGKGTPRNGSPP-----PGAPSSR 71
PG G PP P GPP P +P G P D G G+ P G P S
Sbjct: 1880 PGILGPQGPPGLPGPVGPPGQGFPGVPGGTGPKGDRGETGSKGEQGLPGERGLRGEPGSV 1939
Query: 72 FRVVKLPHGLG----------EPYRRGRWTCVDVYERDLEPHSFGGL-----------LE 110
V +L G E + + + V ER P G
Sbjct: 1940 PNVDRLLETAGIKASALREIVETWDESSGSFLPVPERRRGPKGDSGEQGPPGKEGPIGFP 1999
Query: 111 GIRGASGGAGGRSLDSRLELASLGLGAPTPPSGLSQGPTSWLRPPPTSPGPQARSFTGGL 170
G RG G G LA LG P PSGL+ P P PG R+ GG+
Sbjct: 2000 GERGLKGDRGDPGPQGPPGLA-LGERGPPGPSGLAGEPGK-----PGIPGLPGRA--GGV 2051
Query: 171 GQLVVPSKAKAEKPPLSASSPQQRPPEPETGESAGTSRAATPLPSLRVEAEAGG-SGART 229
G+ P + + E+ Q R P + G P P + V+ G SG +
Sbjct: 2052 GEAGRPGE-RGERGEKGERGEQGRDGPPGLPGTPGP--PGPPGPKVSVDEPGPGLSGEQG 2108
Query: 230 PP 231
PP
Sbjct: 2109 PP 2110
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.309 0.132 0.391
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 23,296,723
Number of Sequences: 37866
Number of extensions: 1740978
Number of successful extensions: 26142
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 491
Number of HSP's successfully gapped in prelim test: 1265
Number of HSP's that attempted gapping in prelim test: 12210
Number of HSP's gapped (non-prelim): 10135
length of query: 395
length of database: 18,247,518
effective HSP length: 104
effective length of query: 291
effective length of database: 14,309,454
effective search space: 4164051114
effective search space used: 4164051114
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.7 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.