Guide to the Human Genome
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Search of human proteins with 61676089

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|61676089 hypothetical protein LOC222584 [Homo sapiens]
         (1011 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|61676089 hypothetical protein LOC222584 [Homo sapiens]            2042   0.0  
gi|157311635 FAM83H [Homo sapiens]                                    259   1e-68
gi|30425394 hypothetical protein LOC128876 [Homo sapiens]             195   2e-49
gi|115392150 hypothetical protein LOC644815 [Homo sapiens]            191   3e-48
gi|116235448 hypothetical protein LOC81610 [Homo sapiens]             177   3e-44
gi|153251792 hypothetical protein LOC54854 [Homo sapiens]             167   4e-41
gi|156564372 hypothetical protein LOC113828 [Homo sapiens]            167   6e-41
gi|46255017 hypothetical protein LOC84985 isoform b [Homo sapiens]    158   2e-38
gi|40254997 hypothetical protein LOC84985 isoform a [Homo sapiens]    157   5e-38
gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens]        47   9e-05
gi|42542379 serine/arginine repetitive matrix 1 [Homo sapiens]         47   1e-04
gi|117935038 cylicin, basic protein of sperm head cytoskeleton 1...    45   3e-04
gi|41872583 Rho-associated, coiled-coil containing protein kinas...    44   8e-04
gi|239753231 PREDICTED: ankyrin repeat domain 36 [Homo sapiens]        44   8e-04
gi|33620745 pre-mRNA cleavage complex II protein Pcf11 [Homo sap...    44   8e-04
gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens]     44   0.001
gi|22035679 AT rich interactive domain 4B isoform 2 [Homo sapiens]     43   0.001
gi|22035677 AT rich interactive domain 4B isoform 1 [Homo sapiens]     43   0.001
gi|55741677 SET domain containing 1A [Homo sapiens]                    43   0.002
gi|217330641 IWS1 homolog [Homo sapiens]                               43   0.002
gi|150378545 POM121 membrane glycoprotein (rat)-like [Homo sapiens]    42   0.002
gi|84043963 eukaryotic translation initiation factor 5B [Homo sa...    42   0.003
gi|5729790 CCCTC-binding factor [Homo sapiens]                         42   0.004
gi|239754624 PREDICTED: similar to hCG1998564 [Homo sapiens]           42   0.004
gi|26051278 nuclear pore membrane protein 121 [Homo sapiens]           42   0.004
gi|89276756 serine/threonine-protein kinase PRP4K [Homo sapiens]       41   0.005
gi|104526627 triadin [Homo sapiens]                                    40   0.011
gi|38146107 arginine/serine-rich coiled-coil 2 isoform a [Homo s...    40   0.011
gi|4758172 dentin matrix acidic phosphoprotein 1 isoform 1 precu...    40   0.014
gi|121256621 dentin matrix acidic phosphoprotein 1 isoform 2 pre...    40   0.014

>gi|61676089 hypothetical protein LOC222584 [Homo sapiens]
          Length = 1011

 Score = 2042 bits (5290), Expect = 0.0
 Identities = 1011/1011 (100%), Positives = 1011/1011 (100%)

Query: 1    METSSMLSSLNDECKSDNYIEPHYKEWYRVAIDILIEHGLEAYQEFLVQERVSDFLAEEE 60
            METSSMLSSLNDECKSDNYIEPHYKEWYRVAIDILIEHGLEAYQEFLVQERVSDFLAEEE
Sbjct: 1    METSSMLSSLNDECKSDNYIEPHYKEWYRVAIDILIEHGLEAYQEFLVQERVSDFLAEEE 60

Query: 61   INYILKNVQKVAQSTAHGTDDSCDDTLSSGTYWPVESDVEAPNLDLGWPYVMPGLLGGTH 120
            INYILKNVQKVAQSTAHGTDDSCDDTLSSGTYWPVESDVEAPNLDLGWPYVMPGLLGGTH
Sbjct: 61   INYILKNVQKVAQSTAHGTDDSCDDTLSSGTYWPVESDVEAPNLDLGWPYVMPGLLGGTH 120

Query: 121  IDLLFHPPRAHLLTIKETIRKMIKEARKVIALVMDIFTDVDIFKEIVEASTRGVSVYILL 180
            IDLLFHPPRAHLLTIKETIRKMIKEARKVIALVMDIFTDVDIFKEIVEASTRGVSVYILL
Sbjct: 121  IDLLFHPPRAHLLTIKETIRKMIKEARKVIALVMDIFTDVDIFKEIVEASTRGVSVYILL 180

Query: 181  DESNFNHFLNMTEKQGCSVQRLRNIRVRTVKGQDYLSKTGAKFHGKMEQKFLLVDCQKVM 240
            DESNFNHFLNMTEKQGCSVQRLRNIRVRTVKGQDYLSKTGAKFHGKMEQKFLLVDCQKVM
Sbjct: 181  DESNFNHFLNMTEKQGCSVQRLRNIRVRTVKGQDYLSKTGAKFHGKMEQKFLLVDCQKVM 240

Query: 241  YGSYSYMWSFEKAHLSMVQIITGQLVESFDEEFRTLYARSCVPSSFAQEESARVKHGKAL 300
            YGSYSYMWSFEKAHLSMVQIITGQLVESFDEEFRTLYARSCVPSSFAQEESARVKHGKAL
Sbjct: 241  YGSYSYMWSFEKAHLSMVQIITGQLVESFDEEFRTLYARSCVPSSFAQEESARVKHGKAL 300

Query: 301  WENGTYQHSVSSLASVSSQRNLFGRQDKIHKLDSSYFKNRGIYTLNEHDKYNIRSHGYKP 360
            WENGTYQHSVSSLASVSSQRNLFGRQDKIHKLDSSYFKNRGIYTLNEHDKYNIRSHGYKP
Sbjct: 301  WENGTYQHSVSSLASVSSQRNLFGRQDKIHKLDSSYFKNRGIYTLNEHDKYNIRSHGYKP 360

Query: 361  HFVPNFNGPNAIRQFQPNQINENWKRHSYAGEQPETVPYLLLNRALNRTNNPPGNWKKPS 420
            HFVPNFNGPNAIRQFQPNQINENWKRHSYAGEQPETVPYLLLNRALNRTNNPPGNWKKPS
Sbjct: 361  HFVPNFNGPNAIRQFQPNQINENWKRHSYAGEQPETVPYLLLNRALNRTNNPPGNWKKPS 420

Query: 421  DSLSVASSSREGYVSHHNTPAQSFANRLAQRKTTNLADRNSNVRRSFNGTDNHIRFLQQR 480
            DSLSVASSSREGYVSHHNTPAQSFANRLAQRKTTNLADRNSNVRRSFNGTDNHIRFLQQR
Sbjct: 421  DSLSVASSSREGYVSHHNTPAQSFANRLAQRKTTNLADRNSNVRRSFNGTDNHIRFLQQR 480

Query: 481  MPTLEHTTKSFLRNWRIESYLNDHSEATPDSNGSALGDRFEGYDNPENLKANALYTHSRL 540
            MPTLEHTTKSFLRNWRIESYLNDHSEATPDSNGSALGDRFEGYDNPENLKANALYTHSRL
Sbjct: 481  MPTLEHTTKSFLRNWRIESYLNDHSEATPDSNGSALGDRFEGYDNPENLKANALYTHSRL 540

Query: 541  RSSLVFKPTLPEQKEVNSCTTGSSNSTIIGSQGSETPKEVPDTPTNVQHLTDKPLPESIP 600
            RSSLVFKPTLPEQKEVNSCTTGSSNSTIIGSQGSETPKEVPDTPTNVQHLTDKPLPESIP
Sbjct: 541  RSSLVFKPTLPEQKEVNSCTTGSSNSTIIGSQGSETPKEVPDTPTNVQHLTDKPLPESIP 600

Query: 601  KLPLQSEAPKMHTLQVPENHSVALNQTTNGHTESNNYIYKTLGVNKQTENLKNQQTENLL 660
            KLPLQSEAPKMHTLQVPENHSVALNQTTNGHTESNNYIYKTLGVNKQTENLKNQQTENLL
Sbjct: 601  KLPLQSEAPKMHTLQVPENHSVALNQTTNGHTESNNYIYKTLGVNKQTENLKNQQTENLL 660

Query: 661  KRRSFPLFDNSKANLDPGNSKHYVYSTLTRNRVRQPEKPKEDLLKSSKSMHNVTHNLEED 720
            KRRSFPLFDNSKANLDPGNSKHYVYSTLTRNRVRQPEKPKEDLLKSSKSMHNVTHNLEED
Sbjct: 661  KRRSFPLFDNSKANLDPGNSKHYVYSTLTRNRVRQPEKPKEDLLKSSKSMHNVTHNLEED 720

Query: 721  EEEVTKRNSPSGTTTKSVSIAALLDVNKEESNKELASKKEVKGSPSFLKKGSQKLRSLLS 780
            EEEVTKRNSPSGTTTKSVSIAALLDVNKEESNKELASKKEVKGSPSFLKKGSQKLRSLLS
Sbjct: 721  EEEVTKRNSPSGTTTKSVSIAALLDVNKEESNKELASKKEVKGSPSFLKKGSQKLRSLLS 780

Query: 781  LTPDKKENLSKNKAPAFYRLCSSSDTLVSEGEENQKPKKSDTKVDSSPRRKHSSSSNSQG 840
            LTPDKKENLSKNKAPAFYRLCSSSDTLVSEGEENQKPKKSDTKVDSSPRRKHSSSSNSQG
Sbjct: 781  LTPDKKENLSKNKAPAFYRLCSSSDTLVSEGEENQKPKKSDTKVDSSPRRKHSSSSNSQG 840

Query: 841  SIHKSKEDVTVSPSQEINAPPDENKRTPSPGPVESKFLERAGDASAPRFNTEQIQYRDSR 900
            SIHKSKEDVTVSPSQEINAPPDENKRTPSPGPVESKFLERAGDASAPRFNTEQIQYRDSR
Sbjct: 841  SIHKSKEDVTVSPSQEINAPPDENKRTPSPGPVESKFLERAGDASAPRFNTEQIQYRDSR 900

Query: 901  EINAVVTPERRPTSSPRPTSSELLRSHSTDRRVYSRFEPFCKIESSIQPTSNMPNTSINR 960
            EINAVVTPERRPTSSPRPTSSELLRSHSTDRRVYSRFEPFCKIESSIQPTSNMPNTSINR
Sbjct: 901  EINAVVTPERRPTSSPRPTSSELLRSHSTDRRVYSRFEPFCKIESSIQPTSNMPNTSINR 960

Query: 961  PEIKSATMGNSYGRSSPLLNYNTGVYRSYQPNENKFRGFMQKFGNFIHKNK 1011
            PEIKSATMGNSYGRSSPLLNYNTGVYRSYQPNENKFRGFMQKFGNFIHKNK
Sbjct: 961  PEIKSATMGNSYGRSSPLLNYNTGVYRSYQPNENKFRGFMQKFGNFIHKNK 1011


>gi|157311635 FAM83H [Homo sapiens]
          Length = 1179

 Score =  259 bits (661), Expect = 1e-68
 Identities = 138/292 (47%), Positives = 182/292 (62%), Gaps = 7/292 (2%)

Query: 1   METSSMLSSLNDECKSDNYIEPHYKEWYRVAIDILIEHGLEAYQEFLVQERVSDFLAEEE 60
           M   S  SS  D   +  Y+ PHYKE+YR+A+D L E G EAY  FL  E   DFL  EE
Sbjct: 1   MARRSQSSSQGDNPLAPGYLPPHYKEYYRLAVDALAEGGSEAYSRFLATEGAPDFLCPEE 60

Query: 61  INYILKNV---QKVAQSTAHGTDDSCDDTLSSGTYWPVESDVEAPNLDLGWPYVMPGLLG 117
           + ++ +++   Q V +    G+    D   SSGTYWPV SD   P LDLGWP        
Sbjct: 61  LEHVSRHLRPPQYVTREPPEGSLLDVDMDGSSGTYWPVNSDQAVPELDLGWPLTFG--FQ 118

Query: 118 GTHIDLLFHPPRAHLLTIKETIRKMIKEARKVIALVMDIFTDVDIFKEIVEASTRGVSVY 177
           GT +  L  PP     +IK+  R+MI+ A++V+A+VMD+FTDVD+  E++EA+ R V VY
Sbjct: 119 GTEVTTLVQPPPPDSPSIKDEARRMIRSAQQVVAVVMDMFTDVDLLSEVLEAAARRVPVY 178

Query: 178 ILLDESNFNHFLNMTEKQGCSVQRLRNIRVRTVKGQDYLSKTGAKFHGKMEQKFLLVDCQ 237
           ILLDE N  HFL+M +K   ++  +  +RVRTV G  Y  +TG  F G +++KFLLVDC 
Sbjct: 179 ILLDEMNAQHFLDMADKCRVNLHHVDFLRVRTVAGPTYYCRTGKSFKGHVKEKFLLVDCA 238

Query: 238 KVMYGSYSYMWSFEKAHLSMVQIITGQLVESFDEEFRTLYARS--CVPSSFA 287
            VM GSYS+MWSFEK H S+  +  G+LV SFDEEFR L+A+S   VPS+ A
Sbjct: 239 VVMSGSYSFMWSFEKIHRSLAHVFQGELVSSFDEEFRILFAQSEPLVPSAAA 290



 Score = 45.4 bits (106), Expect = 3e-04
 Identities = 51/213 (23%), Positives = 85/213 (39%), Gaps = 21/213 (9%)

Query: 750  ESNKELASKKEVKGSPSFLKKGSQKLRSLLSLTPDKK----------ENLSKNKAPAFYR 799
            ES K   +++   G    L+KGS +LR LLS   +++          +   + ++P    
Sbjct: 944  ESPKAGPAEEGPSGPMEVLRKGSLRLRQLLSPKGERRMEDEGGFPVPQENGQPESPRRLS 1003

Query: 800  LCSSSDTLVSEGEENQKPKKSDTKVD---SSPRRKHSSSSNSQGSIHKSKEDVTVSPSQE 856
            L     T  +  E   + + S    +   SS  R  + +   Q S H  K     +PS  
Sbjct: 1004 LGQGDSTEAATEERGPRARLSSATANALYSSNLRDDTKAILEQISAHGQKHRAVPAPSPG 1063

Query: 857  INAPPDENKRTPSPGPVESKFLERAGDASAPRFNTEQIQYRDSREINAVVTPERRPTSSP 916
                  E  R P+ G +     ++   ++  R ++   Q R SR + A        ++  
Sbjct: 1064 PTHNSPELGRPPAAGVLAPDMSDKDKCSAIFRSDSLGTQGRLSRTLPA--------SAEE 1115

Query: 917  RPTSSELLRSHSTDRRVYSRFEPFCKIESSIQP 949
            R      + S   ++RVYSRFE FCK E +  P
Sbjct: 1116 RDRLLRRMESMRKEKRVYSRFEVFCKKEEASSP 1148


>gi|30425394 hypothetical protein LOC128876 [Homo sapiens]
          Length = 747

 Score =  195 bits (496), Expect = 2e-49
 Identities = 109/265 (41%), Positives = 163/265 (61%), Gaps = 9/265 (3%)

Query: 24  YKEWYRVAIDILIEHGLEAYQEFLVQERVSDFLAEEEINYILKNVQKVAQ-STAHGTDDS 82
           + E  R+A D L+E G  AY   + +ER   FL+  +++Y+  +V+   + S A G + S
Sbjct: 41  HSEAARLAADALLERGEAAYLRVISEERELPFLSALDVDYMTSHVRGGPELSEAQGQEAS 100

Query: 83  CDDTLS------SGTYWPVESDVEAPNLDLGWPYVMPGLLGGTHIDLLFHPPRAHLLTIK 136
             D LS      SGTY+P+ SD++ P+LDLGWP V P   G +    + H  R     IK
Sbjct: 101 GPDRLSLLSEVTSGTYFPMASDIDPPDLDLGWPEV-PQATGFSPTQAVVHFQRDKAKNIK 159

Query: 137 ETIRKMIKEARKVIALVMDIFTDVDIFKEIVEASTR-GVSVYILLDESNFNHFLNMTEKQ 195
           + +R +  +A  V+A+VMDIFTD+++  +++EAS+R GV VY+LL + +  HFL M  K 
Sbjct: 160 DLLRFLFSQAHTVVAVVMDIFTDMELLCDLMEASSRRGVPVYLLLAQEHLRHFLEMCYKM 219

Query: 196 GCSVQRLRNIRVRTVKGQDYLSKTGAKFHGKMEQKFLLVDCQKVMYGSYSYMWSFEKAHL 255
             + + L N+RVR+  G  Y SK G +F G+  +KF+L+DC++V+ GSYS+ W   +AH 
Sbjct: 220 DLNGEHLPNMRVRSTCGDTYCSKAGRRFTGQALEKFVLIDCEQVVAGSYSFTWLCSQAHT 279

Query: 256 SMVQIITGQLVESFDEEFRTLYARS 280
           SMV  + G++VE FD EFR LYA S
Sbjct: 280 SMVLQLRGRIVEDFDREFRCLYAES 304


>gi|115392150 hypothetical protein LOC644815 [Homo sapiens]
          Length = 823

 Score =  191 bits (485), Expect = 3e-48
 Identities = 108/302 (35%), Positives = 170/302 (56%), Gaps = 35/302 (11%)

Query: 13  ECKSDNYI---------EPHYKEWYRVAIDILIEHGLEAYQEFLVQERVSDFLAEEEINY 63
           +C  DN++         E  Y E  R+A++ L+  G +A+ E L +E + DFL+E E+  
Sbjct: 7   QCLDDNHVNWRSSESKPEFFYSEEQRLALEALVARGRDAFYEVLKRENIRDFLSELELKR 66

Query: 64  ILKNVQKV--------AQSTAHGTDDSC----------------DDTLSSGTYWPVESDV 99
           IL+ ++              + G +D+                  + L S  YWP +SD 
Sbjct: 67  ILETIEVYDPGSEDPRGTGPSQGPEDNGVGDGEEASGADGVPIEAEPLPSLEYWPQKSDR 126

Query: 100 EAPNLDLGWPYVMPGLLGGTHIDLLFHPPRAHLLTIKETIRKMIKEARKVIALVMDIFTD 159
             P LDLGWP  +    G T   +   PP      IKE +RKMI +A+KVIA+VMD+FTD
Sbjct: 127 SIPQLDLGWPDTI-AYRGVTRASVYMQPPIDGQAHIKEVVRKMISQAQKVIAVVMDMFTD 185

Query: 160 VDIFKEIVEAS-TRGVSVYILLDESNFNHFLNMTEKQGCSVQRLRNIRVRTVKGQDYLSK 218
           VDIFK++++A   R V+VYI++DESN  +FL+M E+    +  L+N+RVR+  G ++ ++
Sbjct: 186 VDIFKDLLDAGFKRKVAVYIIVDESNVKYFLHMCERACMHLGHLKNLRVRSSGGTEFFTR 245

Query: 219 TGAKFHGKMEQKFLLVDCQKVMYGSYSYMWSFEKAHLSMVQIITGQLVESFDEEFRTLYA 278
           +  KF G + QKF+ VD  + + GSYS+ WS  +   +++ +++GQ+VE FD +F+ LY 
Sbjct: 246 SATKFKGALAQKFMFVDGDRAVCGSYSFTWSAARTDRNVISVLSGQVVEMFDRQFQELYL 305

Query: 279 RS 280
            S
Sbjct: 306 MS 307


>gi|116235448 hypothetical protein LOC81610 [Homo sapiens]
          Length = 615

 Score =  177 bits (450), Expect = 3e-44
 Identities = 103/267 (38%), Positives = 166/267 (62%), Gaps = 10/267 (3%)

Query: 24  YKEWYRVAIDILIEHGLEAYQEFLVQERVSDFLAEEEINYILKNVQKVAQ---STAHGTD 80
           + E  R+A++ L+  G EA+  FL +ER++ FL  +E++ IL+  ++  +   + A   +
Sbjct: 58  FSESRRLALEELVAGGPEAFAAFLRRERLARFLNPDEVHAILRAAERPGEEGAAAAAAAE 117

Query: 81  DSCDDT--LSSGTYWPVESDVEAPNLDLGWPYVMPGLL-GGTHIDLLFHPPRAHL---LT 134
           DS   +   SSGTY+P +SD+E P L+LGWP    G   G T ++  F P  A       
Sbjct: 118 DSFGSSHDCSSGTYFPEQSDLEPPLLELGWPAFYQGAYRGATRVETHFQPRGAGEGGPYG 177

Query: 135 IKETIRKMIKEARKVIALVMDIFTDVDIFKEIVEASTR-GVSVYILLDESNFNHFLNMTE 193
            K+ +R+ ++ AR+VIA+VMD+FTD+DIF+++ E   + GV+VYILLD++  + FL+M  
Sbjct: 178 CKDALRQQLRSAREVIAVVMDVFTDIDIFRDLQEICRKQGVAVYILLDQALLSQFLDMCM 237

Query: 194 KQGCSVQRLRNIRVRTVKGQDYLSKTGAKFHGKMEQKFLLVDCQKVMYGSYSYMWSFEKA 253
                 ++ + + VRT+ G  Y +++G K  GK+ +KF L+D  +V  GSYS+ W+  K 
Sbjct: 238 DLKVHPEQEKLMTVRTITGNIYYARSGTKIIGKVHEKFTLIDGIRVATGSYSFTWTDGKL 297

Query: 254 HLSMVQIITGQLVESFDEEFRTLYARS 280
           + S + I++GQ+VE FD EFR LYA+S
Sbjct: 298 NSSNLVILSGQVVEHFDLEFRILYAQS 324


>gi|153251792 hypothetical protein LOC54854 [Homo sapiens]
          Length = 478

 Score =  167 bits (424), Expect = 4e-41
 Identities = 105/300 (35%), Positives = 164/300 (54%), Gaps = 11/300 (3%)

Query: 24  YKEWYRVAIDILIEHGLEAYQEFLVQERVSDFLAEEEINYILKNVQK--VAQSTAHGTDD 81
           Y E  R+A++ L+  G EA+Q  + +E +  FL+ +E+  +    +   VA+    G  +
Sbjct: 27  YSEGQRLALEALLSKGAEAFQTCVQREELWPFLSADEVQGLAAAAEDWTVAKQEPSGMAE 86

Query: 82  SCDDT---LSSGTYWPVESDVEAPNLDLGWPYVMPGLLGGTHIDLLFHPPRAHLLTIKET 138
               T     S +YWP +S+  AP L LGWP V     G T   L   PP      +KE 
Sbjct: 87  GATTTDVDAGSLSYWPGQSEQPAPVLRLGWP-VDSAWKGITRAQLYTQPPGEGQPPLKEL 145

Query: 139 IRKMIKEARKVIALVMDIFTDVDIFKEIVEASTRG-VSVYILLDESNFNHFLNMTEKQGC 197
           +R  I+ A K++A+VMD+FTD D+  ++V+A+TR  V VY+LLD      FL + ++ G 
Sbjct: 146 VRLEIQAAHKLVAVVMDVFTDPDLLLDLVDAATRRWVPVYLLLDRQQLPAFLELAQQLGV 205

Query: 198 SVQRLRNIRVRTVKGQDYLSKTGAKFHGKMEQKFLLVDCQKVMYGSYSYMWSFEKAHLSM 257
           +     N+ VR V+G  + S+   +  G + +KF+L+D ++V+ GSYS+ WS  + H  +
Sbjct: 206 NPWNTENVDVRVVRGCSFQSRWRRQVSGTVREKFVLLDGERVISGSYSFTWSDARLHRGL 265

Query: 258 VQIITGQLVESFDEEFRTLYARSCVPSSFAQEESARVKHGKALWENGTYQHSVSSLASVS 317
           V ++TG++V++F  EFRTLYA SC P   A  +   V  G    + G   H VS   SV+
Sbjct: 266 VTLLTGEIVDAFSLEFRTLYAASC-PLPPAPPQKPSVIGG---LQRGRSPHRVSRRRSVA 321


>gi|156564372 hypothetical protein LOC113828 [Homo sapiens]
          Length = 500

 Score =  167 bits (422), Expect = 6e-41
 Identities = 104/273 (38%), Positives = 156/273 (57%), Gaps = 18/273 (6%)

Query: 23  HYKEWYRVAIDILIEHGLEAYQEFLVQERVSDFLAEEEINYI------------LKNVQK 70
           +Y E  R A++ L+  G +AY+E L +E++ DFL+  E   +              N + 
Sbjct: 26  YYCERRRAALEALLGGGEQAYRERLKEEQLRDFLSSPERQALRAAWSPYEDAVPAANARG 85

Query: 71  VAQSTAHGTDDSCDDTLSSGTYWPVESDVEAPNLDLGWPYVMPGLLGG-THIDLLFHPPR 129
            +++ A     +  ++  S  YWP  SD E P LDLGW     G   G + + L  HPP+
Sbjct: 86  KSKAKAKAPAPAPAESGESLAYWPDRSDTEVPPLDLGWTDT--GFYRGVSRVTLFTHPPK 143

Query: 130 AHLLT-IKETIRKMIKEARKVIALVMDIFTDVDIFKEIVEAST-RGVSVYILLDESNFNH 187
                 +K+ +R+MI++A+KVIA+VMD+FTD DIF++IV+A+  R V VYI+LDE+   +
Sbjct: 144 DEKAPHLKQVVRQMIQQAQKVIAVVMDLFTDGDIFQDIVDAACKRRVPVYIILDEAGVKY 203

Query: 188 FLNMTEKQGCSVQRLRNIRVRTVKGQDYLSKTGAKFHGKMEQKFLLVDCQKVMYGSYSYM 247
           FL M +    +  R+RNIRVR+V G  +    G +  G +  +FL+VD  KV  GSY + 
Sbjct: 204 FLEMCQDLQLTDFRIRNIRVRSVTGVGFYMPMG-RIKGTLSSRFLMVDGDKVATGSYRFT 262

Query: 248 WSFEKAHLSMVQIITGQLVESFDEEFRTLYARS 280
           WS      +++ ++TGQ VE FD EFR LYA S
Sbjct: 263 WSSSHVDRNLLLLLTGQNVEPFDTEFRELYAIS 295


>gi|46255017 hypothetical protein LOC84985 isoform b [Homo sapiens]
          Length = 367

 Score =  158 bits (400), Expect = 2e-38
 Identities = 108/322 (33%), Positives = 159/322 (49%), Gaps = 24/322 (7%)

Query: 29  RVAIDILIEHGLEAYQEFLVQERVSDFLAEEEINYILKNVQKV---------AQSTAHGT 79
           R+A D L++ G EAY   L QE   DFL+  E  YI    ++          A++   G 
Sbjct: 36  RLATDALLDGGSEAYWRVLSQEGEVDFLSSVEAQYIQAQAREPPCPPDTLGGAEAGPKGL 95

Query: 80  DDSCDDTLSSGTYWPVESDVEAPNLDLGW-----PYVMPGLLGGTHIDLLFHPPRAHLLT 134
           D S   +L SGTY+PV S+   P L   W     PY+        +   + H        
Sbjct: 96  DSS---SLQSGTYFPVASEGSEPALLHSWASAEKPYLKEKSSATVYFQTVKHN------N 146

Query: 135 IKETIRKMIKEARKVIALVMDIFTDVDIFKEIVEAST-RGVSVYILLDESNFNHFLNMTE 193
           I++ +R+ I    +V+ ++MD+FTDV+IF +I+EA+  RGV V +LLD+     F  M +
Sbjct: 147 IRDLVRRCITRTSQVLVILMDVFTDVEIFCDILEAANKRGVFVCVLLDQGGVKLFQEMCD 206

Query: 194 KQGCSVQRLRNIRVRTVKGQDYLSKTGAKFHGKMEQKFLLVDCQKVMYGSYSYMWSFEKA 253
           K   S   L+NI +R+V+G+ Y +K+G KF G++ +KF++ D + V+ GSYS+ W     
Sbjct: 207 KVQISDSHLKNISIRSVEGEIYCAKSGRKFAGQIREKFIISDWRFVLSGSYSFTWLCGHV 266

Query: 254 HLSMVQIITGQLVESFDEEFRTLYARSCVPSSFAQEESARVKHGKALWENGTYQHSVSSL 313
           H +++   TGQ VE FDEEFR LYA S                  A   NG    S  S 
Sbjct: 267 HRNILSKFTGQAVELFDEEFRHLYASSKPVMGLKSPRLVAPVPPGAAPANGRLSSSSGSA 326

Query: 314 ASVSSQRNLFGRQDKIHKLDSS 335
           +  +S     GR    H +  S
Sbjct: 327 SDRTSSNPFSGRSAGSHPVPES 348


>gi|40254997 hypothetical protein LOC84985 isoform a [Homo sapiens]
          Length = 434

 Score =  157 bits (397), Expect = 5e-38
 Identities = 107/317 (33%), Positives = 157/317 (49%), Gaps = 24/317 (7%)

Query: 29  RVAIDILIEHGLEAYQEFLVQERVSDFLAEEEINYILKNVQKV---------AQSTAHGT 79
           R+A D L++ G EAY   L QE   DFL+  E  YI    ++          A++   G 
Sbjct: 36  RLATDALLDGGSEAYWRVLSQEGEVDFLSSVEAQYIQAQAREPPCPPDTLGGAEAGPKGL 95

Query: 80  DDSCDDTLSSGTYWPVESDVEAPNLDLGW-----PYVMPGLLGGTHIDLLFHPPRAHLLT 134
           D S   +L SGTY+PV S+   P L   W     PY+        +   + H        
Sbjct: 96  DSS---SLQSGTYFPVASEGSEPALLHSWASAEKPYLKEKSSATVYFQTVKHN------N 146

Query: 135 IKETIRKMIKEARKVIALVMDIFTDVDIFKEIVEAST-RGVSVYILLDESNFNHFLNMTE 193
           I++ +R+ I    +V+ ++MD+FTDV+IF +I+EA+  RGV V +LLD+     F  M +
Sbjct: 147 IRDLVRRCITRTSQVLVILMDVFTDVEIFCDILEAANKRGVFVCVLLDQGGVKLFQEMCD 206

Query: 194 KQGCSVQRLRNIRVRTVKGQDYLSKTGAKFHGKMEQKFLLVDCQKVMYGSYSYMWSFEKA 253
           K   S   L+NI +R+V+G+ Y +K+G KF G++ +KF++ D + V+ GSYS+ W     
Sbjct: 207 KVQISDSHLKNISIRSVEGEIYCAKSGRKFAGQIREKFIISDWRFVLSGSYSFTWLCGHV 266

Query: 254 HLSMVQIITGQLVESFDEEFRTLYARSCVPSSFAQEESARVKHGKALWENGTYQHSVSSL 313
           H +++   TGQ VE FDEEFR LYA S                  A   NG    S  S 
Sbjct: 267 HRNILSKFTGQAVELFDEEFRHLYASSKPVMGLKSPRLVAPVPPGAAPANGRLSSSSGSA 326

Query: 314 ASVSSQRNLFGRQDKIH 330
           +  +S     GR    H
Sbjct: 327 SDRTSSNPFSGRSAGSH 343


>gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens]
          Length = 2752

 Score = 47.0 bits (110), Expect = 9e-05
 Identities = 61/241 (25%), Positives = 94/241 (39%), Gaps = 41/241 (17%)

Query: 747 NKEESNKELASKKEVKG--SPSFLKK--GSQKLRSLLSLTPDKKENLSKNKAPAFYRLCS 802
           + E  NK   S++  +   SP   K    S++ RSL S     K  LS  ++ +    C 
Sbjct: 727 SSERKNKSRTSQRRSRSNSSPEMKKSRISSRRSRSLSSPRSKAKSRLSLRRSLSGSSPCP 786

Query: 803 SSDTLVSEGEENQKPKKSDTKVDSSPRRKHSSSSNSQGSIHKSKEDVTVSPSQEINAPPD 862
              +            +   K  + PRR  SSSS                P Q+   P  
Sbjct: 787 KQKSQTPPRRSRSGSSQPKAKSRTPPRRSRSSSS--------------PPPKQKSKTPSR 832

Query: 863 ENKRTPSPGP-VESKFLERAGDASAPRFNTEQIQYRDSREINAVVTPERRP--TSSPRPT 919
           ++  + SP P V+S    R G  ++P+ N +             VTP+RR    SSP P 
Sbjct: 833 QSHSSSSPHPKVKSGTPPRQGSITSPQANEQS------------VTPQRRSCFESSPDPE 880

Query: 920 SSELLRSHSTDRRVYSRFEPFCKIESSIQPTSNMPNTSINRPEIK---SATMGNSYGRSS 976
               L+S +  R   S   P  +++SS  P  +   +S  +P++K   S    +  G SS
Sbjct: 881 ----LKSRTPSRHSCSGSSP-PRVKSSTPPRQSPSRSSSPQPKVKAIISPRQRSHSGSSS 935

Query: 977 P 977
           P
Sbjct: 936 P 936



 Score = 43.1 bits (100), Expect = 0.001
 Identities = 48/215 (22%), Positives = 76/215 (35%), Gaps = 31/215 (14%)

Query: 726  KRNSPSGTTTKSVSIAALLDVNKEESNKELASKKEVKGSPSFLKKGSQKLRSLLSLTPDK 785
            +R+S S +++ S S ++    +   S+   +S  E    P    +    L+ + S TP  
Sbjct: 2530 RRSSSSSSSSSSSSSSSSSSSSSSSSSGSSSSDSEGSSLPV---QPEVALKRVPSPTPAP 2586

Query: 786  KENLSKNKAPA--------FYRLCSSSDTLVSEGEENQKPKKSDTKVDSSPRRKHSSSSN 837
            KE + + + P              SSS +  S    +     S +   SS     SSSS+
Sbjct: 2587 KEAVREGRPPEPTPAKRKRRSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2646

Query: 838  SQGSIHKSKEDVTVSPSQEINAPPDENKRTPSPGPVESKFLERAGDASAPRFNTEQIQYR 897
            S  S  K        P+     PP E +      P++S                     R
Sbjct: 2647 SSPSPAKPGPQALPKPASPKKPPPGERRSRSPRKPIDS--------------------LR 2686

Query: 898  DSREINAVVTPERRPTSSPRPTSSELLRSHSTDRR 932
            DSR ++      RRP+  P P   +   S    RR
Sbjct: 2687 DSRSLSYSPVERRRPSPQPSPRDQQSSSSERGSRR 2721



 Score = 36.6 bits (83), Expect = 0.12
 Identities = 72/375 (19%), Positives = 146/375 (38%), Gaps = 32/375 (8%)

Query: 630  GHTESNNYIYKTLGVNKQTENLKNQQTENLLKRRSFPLFDNSKANLDPGNSKHYVYSTLT 689
            G + S + + +    ++  +      + +  K +S      S++N  P   K  + S  +
Sbjct: 700  GRSRSRSLVRRGRSHSRTPQRRGRSGSSSERKNKSRTSQRRSRSNSSPEMKKSRISSRRS 759

Query: 690  RNRVRQPEKPKEDLLKSSKSMHNVTHNLEEDEEEVTKRNSPSGTTTKSVSIAALLDVNKE 749
            R+ +  P    +  L   +S+   +    + + +   R S SG++       +     + 
Sbjct: 760  RS-LSSPRSKAKSRLSLRRSLSG-SSPCPKQKSQTPPRRSRSGSSQPKAK--SRTPPRRS 815

Query: 750  ESNKELASKKEVKGSPSFLKKGSQKLRSLLSLTPDKKENLSK---NKAPAFYRLCSSSDT 806
             S+     K++ K         S     + S TP ++ +++    N+     +  S  ++
Sbjct: 816  RSSSSPPPKQKSKTPSRQSHSSSSPHPKVKSGTPPRQGSITSPQANEQSVTPQRRSCFES 875

Query: 807  LVSEGEENQKPKKSDTKVDSSPRRKHSS---SSNSQGSIHKSKEDVTVSPSQEINAPPDE 863
                  +++ P +      S PR K S+    S S+ S  + K    +SP Q  ++    
Sbjct: 876  SPDPELKSRTPSRHSCSGSSPPRVKSSTPPRQSPSRSSSPQPKVKAIISPRQRSHS---- 931

Query: 864  NKRTPSPGPVESKFLERAGDASAPRFNTE-QIQYRDSREINAVVTPERRPTSSPRPTSSE 922
               +PSP  V S+   R   + +P  N E ++  R S   ++    + +P + PR     
Sbjct: 932  GSSSPSPSRVTSRTTPRRSRSVSPCSNVESRLLPRYSHSGSSSPDTKVKPETPPR----- 986

Query: 923  LLRSHSTDRRVYSRFEPFCKIESSIQPTSNMPNTSINRPEIKSATMGNSYGRSSP-LLNY 981
              +SHS          P+ K+++   P  ++  +    P+ KS    +S  +S P  L+ 
Sbjct: 987  --QSHS------GSISPYPKVKAQTPPGPSLSGSKSPCPQEKSK---DSLVQSCPGSLSL 1035

Query: 982  NTGVYRSYQPNENKF 996
              GV  S  P E+ F
Sbjct: 1036 CAGVKSSTPPGESYF 1050



 Score = 34.7 bits (78), Expect = 0.47
 Identities = 71/308 (23%), Positives = 118/308 (38%), Gaps = 51/308 (16%)

Query: 697  EKPKEDLLKSSKSMHNVTHNLEEDEEEVTKRNSPSGTTTKSVSIAALLDVNKEE-SNKEL 755
            EK K+ L++S     ++   +        K ++P G +   VS   L   ++    ++  
Sbjct: 1019 EKSKDSLVQSCPGSLSLCAGV--------KSSTPPGESYFGVSSLQLKGQSQTSPDHRSD 1070

Query: 756  ASKKEVKGSPSFLKKGSQKLRSLLSLTPDKKENLSKNKAPAFYRLCSSSDTLVSEGE--- 812
             S  EV+ S S     S  L+S    +P  K   S++ +P    L S S      GE   
Sbjct: 1071 TSSPEVRQSHS----ESPSLQSKSQTSP--KGGRSRSSSPVT-ELASRSPIRQDRGEFSA 1123

Query: 813  -----ENQKPKKSDTKVDSSPRRKHSSSS---NSQGSIHKSKEDVTVSPSQEINAPPDEN 864
                     P++S  + DSS      S+S    S+    +SKE + + P ++  A P   
Sbjct: 1124 SPMLKSGMSPEQSRFQSDSSSYPTVDSNSLLGQSRLETAESKEKMALPPQEDATASPPRQ 1183

Query: 865  KRTPSPGPV----ESKFL----------ERAGDASAPRFNTEQIQYRDS---REINAVVT 907
            K   SP PV    ES  +          ER+G  S+P    +      S    E+  VV 
Sbjct: 1184 KDKFSPFPVQDRPESSLVFKDTLRTPPRERSGAGSSPETKEQNSALPTSSQDEELMEVVE 1243

Query: 908  PERRPTSSPRPTSSELLRSHSTDRRVYSRFEPFCKIES--SIQPTSNMPNTSINRPEIKS 965
                P        S  L+  ST     S FE   ++E   ++  T +   +  +   ++ 
Sbjct: 1244 KSEEPAGQILSHLSSELKEMST-----SNFESSPEVEERPAVSLTLDQSQSQASLEAVEV 1298

Query: 966  ATMGNSYG 973
             +M +S+G
Sbjct: 1299 PSMASSWG 1306



 Score = 33.5 bits (75), Expect = 1.0
 Identities = 85/349 (24%), Positives = 119/349 (34%), Gaps = 62/349 (17%)

Query: 695 QPEKPKEDLLKSSKSMHNVTHNLEEDEEEVTKRNSPSGTTTKSVSIAALLDVNKEESNKE 754
           +P KP   + +SS S        ++ +++   R S S +  +    ++     K++   E
Sbjct: 166 EPPKPYSLVRESSSSRSPTPKQKKKKKKKDRGRRSESSSPRRERKKSS----KKKKHRSE 221

Query: 755 LASKKEVKGSP---SFLKKGSQKLRSLLSLTPDKKENLSKNKAPAFYRLCSSSDTLVSE- 810
             SKK    SP   S  K   +K +   S TP  K   +     A     SSSDT  S  
Sbjct: 222 SESKKRKHRSPTPKSKRKSKDKKRKRSRSTTPAPKSRRAHRSTSA--DSASSSDTSRSRS 279

Query: 811 ------------------------GEEN---QKPKKSDTKVDSSPR---RKHSSSSNSQG 840
                                   GE +    +P  + T+  SSP    ++ SS    + 
Sbjct: 280 RSAAAKTHTTALAGRSPSPASGRRGEGDAPFSEPGTTSTQRPSSPETATKQPSSPYEDKD 339

Query: 841 SIHKSKEDVTVSPSQEINAPPDENKRTPSPGPVESKFLERAGDASAPRFNTEQIQYRDSR 900
              K K     SPS E ++   E    P+P P+     ER G +  P   T   Q   + 
Sbjct: 340 KDKKEKSATRPSPSPERSSTGPE---PPAPTPL---LAERHGGSPQPLATTPLSQEPVNP 393

Query: 901 EINAVVTPERRPTSSPR--PTSSELLRS------HSTDRRVYSRFE-------PFCKIES 945
              A  T +R P  SP   P SS    S          R   S  E       P    E 
Sbjct: 394 PSEASPTRDRSPPKSPEKLPQSSSSESSPPSPQPTKVSRHASSSPESPKPAPAPGSHREI 453

Query: 946 SIQPTS-NMPNTSINRPEIKSATMGNSYGRSSPLLNYNTGVYRSYQPNE 993
           S  PTS N  +    R +  S T     GRS        G  RS  P +
Sbjct: 454 SSSPTSKNRSHGRAKRDKSHSHTPSRRMGRSRSPATAKRGRSRSRTPTK 502


>gi|42542379 serine/arginine repetitive matrix 1 [Homo sapiens]
          Length = 904

 Score = 46.6 bits (109), Expect = 1e-04
 Identities = 75/311 (24%), Positives = 117/311 (37%), Gaps = 37/311 (11%)

Query: 694 RQPEKPKEDLLKSSKSMHNVTHNLEEDEEEVTKRNSPSGTTTKSVSIAALLDVNKEESNK 753
           R+  +P        K+ H+ T        +     SP  T+ K   +       K ES  
Sbjct: 396 RRRHRPSPPATPPPKTRHSPTPQQSNRTRKSRVSVSPGRTSGK---VTKHKGTEKRESPS 452

Query: 754 ELASKKEVKGSPSFLKKGSQKLRSLLSLTPDKKENLSKNKAPAFYRLCSSSDTLVSEGEE 813
                ++V+ S S   KG +   +       +++   +N+        SSSD+  S   E
Sbjct: 453 PAPKPRKVELSESEEDKGGKMAAA--DSVQQRRQYRRQNQQ-------SSSDSGSSSSSE 503

Query: 814 NQKPKKSDTK-VDSSPRRKHSSSSNSQGSIHKSKEDVTV------SPSQEINAPPDENKR 866
           +++PK+S  K  +   RR+HS S ++  S  K +++ +       SPS     PP   +R
Sbjct: 504 DERPKRSHVKNGEVGRRRRHSPSRSASPSPRKRQKETSPRGRRRRSPS----PPPTRRRR 559

Query: 867 TPSPGPVESKFLERAGDASAPRFNTEQIQYRDSREINAVVTP--ERRPTSSPRPTSSELL 924
           +PSP P   +   R      PR  T     R         +P  +RR + SP P      
Sbjct: 560 SPSPAPPPRR---RRTPTPPPRRRTPSPPPRRRSPSPRRYSPPIQRRYSPSPPPKRRTAS 616

Query: 925 RSHSTDRRVYSRFEPFCKIESSIQPTS-NMPNTSINRPEIKSA-TMGNSYGRSSPLLNYN 982
                 RR      P  ++  S  P   + P T    P + S    G+S  RS       
Sbjct: 617 PPPPPKRRASPSPPPKRRVSHSPPPKQRSSPVTKRRSPSLSSKHRKGSSPSRS------- 669

Query: 983 TGVYRSYQPNE 993
           T   RS QPN+
Sbjct: 670 TREARSPQPNK 680



 Score = 38.1 bits (87), Expect = 0.042
 Identities = 48/232 (20%), Positives = 89/232 (38%), Gaps = 33/232 (14%)

Query: 755 LASKKEVKGSPSF---LKKGSQKLRSLLS--LTPDKKENLSKNKAPAFYRLCSSSDTLVS 809
           L++++ + G PS    LKK   K R +    L   KK++  K+K     +  S      S
Sbjct: 110 LSAQENIAGIPSAFLELKKEEIKQRQIEQEKLASMKKQDEDKDKRDKEEKESSREKRERS 169

Query: 810 EGEENQKPKKSDTKVDSSPRRKHSSSSNSQGSIHKSKEDVTVSPSQEINAPPDENKRTPS 869
                +K +    +  SSP R+    S+S+   H++K                   R+PS
Sbjct: 170 RSPRRRKSRSPSPRRRSSPVRRERKRSHSRSPRHRTK------------------SRSPS 211

Query: 870 PGPVESKFLERAGDASAPRFNTEQIQYRDSREINAVV-TPERRPTSSPRPTSSELLRSHS 928
           P P +    E+  +   P    ++   +++   + ++  P+  P   P+  S E    +S
Sbjct: 212 PAPEKK---EKTPELPEPSVKVKEPSVQEATSTSDILKVPKPEPIPEPKEPSPE---KNS 265

Query: 929 TDRRVYSRFEPFCKIESSIQPTSNMPNTSINRPEIKSATMGNSYG---RSSP 977
              +   +  P  +  S  +  +   + S  RP  +  +   SY    R SP
Sbjct: 266 KKEKEKEKTRPRSRSRSKSRSRTRSRSPSHTRPRRRHRSRSRSYSPRRRPSP 317



 Score = 36.2 bits (82), Expect = 0.16
 Identities = 101/488 (20%), Positives = 162/488 (33%), Gaps = 71/488 (14%)

Query: 537 HSRLRSSLVFKPTLPEQKEVNSCTTGSSNSTIIGSQGSETPKEVPDTPTNVQHLTDKPLP 596
           H R RS +        ++  +S +   S+S+   S+    PK+ P   ++    T +  P
Sbjct: 338 HRRSRSPV-------RRRRRSSASLSGSSSSSSSSRSRSPPKKPPKRTSSPPRKTRRLSP 390

Query: 597 ESIPKLPLQSEAPKMHTLQVPENHSVALNQTTNGHTESNNYIYKTLGVNKQTENLKNQQT 656
            + P  P +   P       P+       Q +N   +S   +       K T++   ++ 
Sbjct: 391 SASP--PRRRHRPSPPATPPPKTRHSPTPQQSNRTRKSRVSVSPGRTSGKVTKHKGTEKR 448

Query: 657 ENLLKRRSFPLFDNSKANLDPGNSKHYVYSTLTRNRVR----------------QPEKPK 700
           E+          + S++  D G       S   R + R                + E+PK
Sbjct: 449 ESPSPAPKPRKVELSESEEDKGGKMAAADSVQQRRQYRRQNQQSSSDSGSSSSSEDERPK 508

Query: 701 EDLLKSS----KSMHNVTHNLEEDEEEVTKRNSPSGTTTKSVSIAALLDVNKEES----- 751
              +K+     +  H+ + +      +  K  SP G   +S S                 
Sbjct: 509 RSHVKNGEVGRRRRHSPSRSASPSPRKRQKETSPRGRRRRSPSPPPTRRRRSPSPAPPPR 568

Query: 752 ---------NKELASKKEVKGSPSFLKKGSQKLRSLLSLTPDKKENLSKNKAPAFYRLCS 802
                     +   S    + SPS  +      R      P K+   S    P   R  S
Sbjct: 569 RRRTPTPPPRRRTPSPPPRRRSPSPRRYSPPIQRRYSPSPPPKRRTASPPPPPK--RRAS 626

Query: 803 SSDTLVSEGEENQKPKKSDTKVD-------SSPRRKHSSSSNSQGSIHKSKEDVTVSPSQ 855
            S         +  PK+  + V        SS  RK SS S S       + +   SPS 
Sbjct: 627 PSPPPKRRVSHSPPPKQRSSPVTKRRSPSLSSKHRKGSSPSRSTREARSPQPNKRHSPSP 686

Query: 856 EINAPPDENKRTPSPGPVESKFLERAGDASAPRFNTEQIQYRDSREINAVVTPER-RPTS 914
              AP    + + SP PV      R   +S  R  +     R  R ++    P++ +  +
Sbjct: 687 RPRAP----QTSSSPPPV-----RRGASSSPQRRQSPSPSTRPIRRVSRTPEPKKIKKAA 737

Query: 915 SPRPTSSELLRSHSTDRRVYSRFEPFCK----IESSIQPTSNMPNTSINRP--EIKSATM 968
           SP P S   +R  S+ R V    EP  K      S +Q  S   N S   P  + KS T 
Sbjct: 738 SPSPQS---VRRVSSSRSVSGSPEPAAKKPPAPPSPVQSQSPSTNWSPAVPVKKAKSPTP 794

Query: 969 GNSYGRSS 976
             S  R+S
Sbjct: 795 SPSPPRNS 802



 Score = 33.9 bits (76), Expect = 0.79
 Identities = 45/221 (20%), Positives = 86/221 (38%), Gaps = 19/221 (8%)

Query: 699 PKEDLLKSSKSMHNVTHNLEEDEEEVTKRNSPSGTTTKSVSIAALLDVNKEESNKELASK 758
           PK + +   K      ++ +E E+E T+  S S + ++S + +      +        S+
Sbjct: 248 PKPEPIPEPKEPSPEKNSKKEKEKEKTRPRSRSRSKSRSRTRSRSPSHTRPRRRHRSRSR 307

Query: 759 K-EVKGSPSFLKKGSQKLRSLLSLTPDKKENLSKNKAPAFYRLCSS-----SDTLVSEGE 812
               +  PS  ++ S + R+     P    +  ++++P   R  SS     S +  S   
Sbjct: 308 SYSPRRRPSPRRRPSPRRRTPPRRMPPPPRH-RRSRSPVRRRRRSSASLSGSSSSSSSSR 366

Query: 813 ENQKPKKSDTKVDSSPR--RKHSSSSNSQGSIHKSKEDVTVSPSQEINAPPDENKRT--- 867
               PKK   +  S PR  R+ S S++     H+     T  P    +  P ++ RT   
Sbjct: 367 SRSPPKKPPKRTSSPPRKTRRLSPSASPPRRRHRPSPPATPPPKTRHSPTPQQSNRTRKS 426

Query: 868 ---PSPGPVESKFLERAG----DASAPRFNTEQIQYRDSRE 901
               SPG    K  +  G    ++ +P     +++  +S E
Sbjct: 427 RVSVSPGRTSGKVTKHKGTEKRESPSPAPKPRKVELSESEE 467


>gi|117935038 cylicin, basic protein of sperm head cytoskeleton 1
           [Homo sapiens]
          Length = 651

 Score = 45.1 bits (105), Expect = 3e-04
 Identities = 48/217 (22%), Positives = 91/217 (41%), Gaps = 23/217 (10%)

Query: 679 NSKHYVYSTLTRNRVRQPEKPKEDLLKSSKSMHNVTHNLEEDEEEVTKRNSPSGTTTKSV 738
           ++K   +ST + + +   E  K++      S  +   +++ DEE     + P G + K  
Sbjct: 399 DAKKITFSTDSESELESKESQKDEKKDKKDSKTDNKKSVKNDEESTDADSEPKGDSKKG- 457

Query: 739 SIAALLDVNKEESNKELASKKEVKGSPSFLKKGSQKLRSLLSLTPDKKENLSKNKAPAFY 798
                    K+E   +  SKK+ K   +     S ++ S L L  DKK +  K  +    
Sbjct: 458 --------KKDEKKGKKDSKKDDKKKDAKKNAESTEMESDLELKKDKKHSKEKKGSKKDI 509

Query: 799 RLCSSSDTLVSEGEENQKPK---KSDTKVDSSPRRKHSSSSNSQGSIHK--SKEDVTVSP 853
           +  +  DT  ++ E ++  K   K+ TK+         S + S+ S++K  +K+ +  S 
Sbjct: 510 KKDARKDTESTDAEFDESSKTGFKTSTKI-------KGSDTESEESLYKPGAKKKIDESD 562

Query: 854 SQEINAPPD--ENKRTPSPGPVESKFLERAGDASAPR 888
               N+  +  E+KR       ++ F E+   AS  R
Sbjct: 563 GTSANSKMEGLESKRGFRMSSKKTTFNEKGEKASTGR 599



 Score = 38.9 bits (89), Expect = 0.025
 Identities = 61/317 (19%), Positives = 110/317 (34%), Gaps = 42/317 (13%)

Query: 668 FDNSKANLDPGNSKHYV--YSTLTR-----NRVRQPEKPKEDLLKSSKSMHNVTHNLEED 720
           FD    N    NSK+Y   Y+  T+     N  +  +   ED   + K    V  N+++D
Sbjct: 261 FDAWLRNYSQNNSKNYSLKYTKYTKKDTKKNAKKSSDAESEDSKDAKKDSKKVKKNVKKD 320

Query: 721 EEEVTKRNSPSGTT------------TKSVSIAALLDVNKEESNKELASKKEVKGSPSFL 768
           +++   +     T             TK        D  K+++ K   S     G     
Sbjct: 321 DKKKDVKKDTESTDAESGDSKDERKDTKKDKKKLKKDDKKKDTKKYPESTDTESGDAKDA 380

Query: 769 KKGSQKLRSLLSLTPDKKENLSKNKAPAFYRLCSSSDTLVSEGEENQKPKKSDTKVDSSP 828
           +  S+ L+   S   DKK++  K      +   S S+    E ++++K  K D+K D+  
Sbjct: 381 RNDSRNLKKA-SKNDDKKKDAKK----ITFSTDSESELESKESQKDEKKDKKDSKTDNKK 435

Query: 829 RRKHSSSSNSQGSIHKSKEDVTVSPSQEINAPPDENKRTPSPGPVESKFLERAGDASAPR 888
             K+   S    S              E      + K+    G  +SK  ++  DA   +
Sbjct: 436 SVKNDEESTDADS--------------EPKGDSKKGKKDEKKGKKDSKKDDKKKDA---K 478

Query: 889 FNTEQIQYRDSREINAVVTPERRPTSSPRPTSSELLR-SHSTDRRVYSRFEPFCKIESSI 947
            N E  +     E+       +    S +    +  + + STD       +   K  + I
Sbjct: 479 KNAESTEMESDLELKKDKKHSKEKKGSKKDIKKDARKDTESTDAEFDESSKTGFKTSTKI 538

Query: 948 QPTSNMPNTSINRPEIK 964
           + +      S+ +P  K
Sbjct: 539 KGSDTESEESLYKPGAK 555



 Score = 33.1 bits (74), Expect = 1.4
 Identities = 25/92 (27%), Positives = 45/92 (48%), Gaps = 7/92 (7%)

Query: 757 SKKEVKGSPSFLKKGSQKLRSLLSLTPDKKENLSKNKAPAFYRLCSSSDTLVSEGEENQK 816
           SK E  G+P  LKK S+K     +  P+ K+ + +       R   +  T +    EN++
Sbjct: 118 SKDEKGGTP--LKKDSKKKGGSYATNPESKQIVEEKTK----RQNEADKTPLKSSHENEQ 171

Query: 817 PKKSDTKVDSSPRRKHSSSSNSQGSIHKSKED 848
            KKS +  +++P  ++S +  S+    K K+D
Sbjct: 172 SKKSKSSSETNPESQNSKTV-SKNCSQKDKKD 202


>gi|41872583 Rho-associated, coiled-coil containing protein kinase 2
            [Homo sapiens]
          Length = 1388

 Score = 43.9 bits (102), Expect = 8e-04
 Identities = 85/448 (18%), Positives = 172/448 (38%), Gaps = 52/448 (11%)

Query: 503  DHSEATPDSNGSALGDRFEGYDNPENLKANALYTHSRLRSSLVFKPTLPEQKEVNSCTTG 562
            +  EA   +  + L D+ + Y++ E  K+ A+     +   L+ + TL +QK  N     
Sbjct: 702  EQEEAEHKATKARLADKNKIYESIEEAKSEAM---KEMEKKLLEERTL-KQKVENLLLEA 757

Query: 563  SSNSTIIGSQGSETPKEVPDT-------PTNVQHLTDKPLPESIPKLPLQSEAPKMHTLQ 615
                +++     ++ +++ +          +V++LT K   E+  +   Q++  KM T Q
Sbjct: 758  EKRCSLLDCDLKQSQQKINELLKQKDVLNEDVRNLTLKIEQETQKRCLTQNDL-KMQTQQ 816

Query: 616  VPENHSVALNQTTNGHTESNNYIYKT-LGVNKQTENLKNQQTENLLKRRSFPLFDNSKAN 674
            V       L  +     + NN++ +  + + KQ   L+ ++ +           D     
Sbjct: 817  VN-----TLKMSEKQLKQENNHLMEMKMNLEKQNAELRKERQDA----------DGQMKE 861

Query: 675  LDPGNSKHYVYSTLTRNRVRQPEKPKEDLLKSSKSMHNVTHNLEEDEE------EVTKRN 728
            L         +STL + +VR+ ++  E+  K  K +      L+++ +      E+T   
Sbjct: 862  LQDQLEAEQYFSTLYKTQVRELKEECEEKTKLGKELQQKKQELQDERDSLAAQLEITLTK 921

Query: 729  SPSGTTTKSVSIAALLDVNKEESNKELASKK----------EVKGSPSFLKKGSQKLRSL 778
            + S    +S++     D+ KE+  KEL  K+          E   + + L++ ++ L S 
Sbjct: 922  ADSEQLARSIAEEQYSDLEKEKIMKELEIKEMMARHKQELTEKDATIASLEETNRTLTSD 981

Query: 779  LSLTPDKKENLSKNKAPAFYRLCSSSDTLVSEGEENQKPKKSDTKVDSSPRRKHSSSSNS 838
            ++   ++KE L+        +L    D  +S        K    K   + R   + + N 
Sbjct: 982  VANLANEKEELNNKLKDVQEQLSRLKDEEISAA----AIKAQFEKQLLTERTLKTQAVNK 1037

Query: 839  QGSIHKSKEDVTVSPSQEINAPPDENKRTPSPGPVESKFLERAGDASAPRFNTEQIQYRD 898
               I   KE V      ++     EN++       E + L +         N  Q Q  +
Sbjct: 1038 LAEIMNRKEPVKRGNDTDVRRKEKENRKLHMELKSEREKLTQQMIKYQKELNEMQAQIAE 1097

Query: 899  SREINAVVTPERRPTSSPRPTSSELLRS 926
              +I      E + T   + +  E LRS
Sbjct: 1098 ESQIRI----ELQMTLDSKDSDIEQLRS 1121


>gi|239753231 PREDICTED: ankyrin repeat domain 36 [Homo sapiens]
          Length = 948

 Score = 43.9 bits (102), Expect = 8e-04
 Identities = 53/230 (23%), Positives = 96/230 (41%), Gaps = 25/230 (10%)

Query: 627 TTNGHTESNNYIYKTLGVNKQTENLKNQQTENL--LKRRSFPLFDNSKANLDPGNSKHYV 684
           T  G ++  + +      NK  E  +   +E    LK  S    D   + L+    K Y 
Sbjct: 543 TLKGTSDEEDSVLGIARENKDGEKSRTVSSEKPPGLKASS----DEKDSVLNIARGKKYG 598

Query: 685 YSTLTRNRVRQPEKPKEDLLKSSK-SMHNVTHNLEEDE--EEVTKRNSPS--GTTTKSVS 739
             T    RV   +KP  +     K S  N+T   ++ E   +V+ +  P+  GT+ +  S
Sbjct: 599 EKT---KRVSSRKKPSLEATSDEKDSFSNITREKKDGEISRKVSSQKPPALKGTSDEEDS 655

Query: 740 IAALLDVNKE-ESNKELASKKEVKGSPSFLKKGSQKLRSLLSLTPDKKEN-----LSKNK 793
           +  +   NK+ E ++ ++S+K     P  LK  S +  S+L++   KK+      +S  K
Sbjct: 656 VLGIARENKDGEKSRTVSSEK-----PPGLKATSDEKDSVLNIARGKKDGEKTRTVSSQK 710

Query: 794 APAFYRLCSSSDTLVSEGEENQKPKKSDTKVDSSPRRKHSSSSNSQGSIH 843
            P         D+++S   EN+  +KS T     P    ++S+     ++
Sbjct: 711 PPTLKATSDEEDSVLSIARENKDGEKSRTVSSEKPSGLKATSAEKDSVLN 760



 Score = 38.1 bits (87), Expect = 0.042
 Identities = 33/152 (21%), Positives = 62/152 (40%), Gaps = 12/152 (7%)

Query: 716 NLEEDEEEVTKRNSPSGTTTKSVSIAALLDVNKEESNKELASKKEVKGSPSFLKKGSQKL 775
           N + ++        PSG    S    ++L++ + +   E   +   +  P+ LK  S + 
Sbjct: 731 NKDGEKSRTVSSEKPSGLKATSAEKDSVLNIARGKKYGEKTKRVSSRKKPA-LKATSDEK 789

Query: 776 RSLLSLTPDKKEN-----LSKNKAPAFYRLCSSSDTLVSEGEENQKPKKSDTKVD----- 825
            S+L +  +KK+      +S  K PA   +C   D++ +   E +  + S T        
Sbjct: 790 DSVLYIAREKKDGEKSRTVSSQKQPALKAICDKEDSVPNMATEKKDEQISGTVSSQKQPA 849

Query: 826 -SSPRRKHSSSSNSQGSIHKSKEDVTVSPSQE 856
             +   K  S SN    I   ++  TVSP ++
Sbjct: 850 LKATSDKKDSVSNIPTEIKDGQQSGTVSPQKQ 881



 Score = 32.3 bits (72), Expect = 2.3
 Identities = 29/141 (20%), Positives = 56/141 (39%), Gaps = 7/141 (4%)

Query: 709 SMHNVTHNLEEDEEEVT-KRNSPSGTTTKSVSIAALLDVNKEESNKELASKKEVKGSPSF 767
           S+ N+   +++ E+  T     P   T  S    ++L + +E  + E +     +  P+ 
Sbjct: 451 SVSNIATEIKDGEKSGTVSSQKPPALTATSDEEGSVLSIARENKDGEKSRTVSSRKKPAS 510

Query: 768 LKKGSQKLRSLLSLTPDKKEN-----LSKNKAPAFYRLCSSSDTLVSEGEENQKPKKSDT 822
            K  S +  S  ++T  KK+      +S  K P         D+++    EN+  +KS T
Sbjct: 511 -KATSDEKDSFSNITRGKKDGEISRKVSSQKPPTLKGTSDEEDSVLGIARENKDGEKSRT 569

Query: 823 KVDSSPRRKHSSSSNSQGSIH 843
                P    +SS      ++
Sbjct: 570 VSSEKPPGLKASSDEKDSVLN 590



 Score = 30.4 bits (67), Expect = 8.8
 Identities = 35/150 (23%), Positives = 58/150 (38%), Gaps = 25/150 (16%)

Query: 732 GTTTKSVSIAALLDVNKEESNKELASKKEVKGSPSFLKKGSQKLRSLLSLTPDKKE---- 787
           GT +     A     ++E+S   +A+  E+K         SQK  +L + T +K      
Sbjct: 398 GTVSSQKQPALKATTDEEDSVSNIAT--EIKDGEKSGTVSSQKQPALKATTDEKDSVSNI 455

Query: 788 -----------NLSKNKAPAFYRLCSSSDTLVSEGEENQKPKKSDTKVDSSPRRKHSSSS 836
                       +S  K PA         +++S   EN+  +KS T    S R+K +S +
Sbjct: 456 ATEIKDGEKSGTVSSQKPPALTATSDEEGSVLSIARENKDGEKSRT---VSSRKKPASKA 512

Query: 837 NSQ-----GSIHKSKEDVTVSPSQEINAPP 861
            S       +I + K+D  +S       PP
Sbjct: 513 TSDEKDSFSNITRGKKDGEISRKVSSQKPP 542


>gi|33620745 pre-mRNA cleavage complex II protein Pcf11 [Homo
           sapiens]
          Length = 1555

 Score = 43.9 bits (102), Expect = 8e-04
 Identities = 78/419 (18%), Positives = 154/419 (36%), Gaps = 41/419 (9%)

Query: 563 SSNSTIIGSQGSETPKEVPDTPTNV---QHLTDKPLPESIPKLPLQSEAPKMHTLQVPEN 619
           S+  T++ S    TP  VPD   N+   Q +  + L +    L LQ +  ++   Q    
Sbjct: 174 STPGTVVSSPSISTPPIVPDIQKNLTQEQLIRQQLLAKQKQLLELQQKKLELELEQAKAQ 233

Query: 620 HSVALN---QTTN---GHTESNNYIYKTLGVNKQTENLKNQQTENLLKRRSFPLFDNSKA 673
            +V+L+   +T+N   G   S  ++ +   +  +  +    Q+E      S  + D    
Sbjct: 234 LAVSLSVQQETSNLGPGSAPSKLHVSQIPPMAVKAPHQVPVQSEKSRPGPSLQIQDLKGT 293

Query: 674 NLDP--------------GNSKHYVYSTLTRNRVRQPEKPKEDLLKSSKSMHNVTHNLEE 719
           N DP               + K ++ +TL ++  +  +    + L SSK   + +   + 
Sbjct: 294 NRDPRLNRISQHSHGKDQSHRKEFLMNTLNQSDTKTSKTIPSEKLNSSKQEKSKSGE-KI 352

Query: 720 DEEEVTKRNSPSGTTTKSVSIAALLDVNKEESNKELASKKEVKGSPSFLKKGSQKLRSLL 779
            ++E+ + +S S + +KS S       NK    K+L +++      S + K   +L+  L
Sbjct: 353 TKKELDQLDSKSKSKSKSPSPLK----NKLSHTKDLKNQESESMRLSDMNKRDPRLKKHL 408

Query: 780 SLTPDKKENLSKNKAPAF-------------YRLCSSSDTLVSEGEENQKPKKSDTKVDS 826
               D K++  K K                 +RL  S + +++   + Q     +++   
Sbjct: 409 QDKTDGKDDDVKEKRKTAEKKDKDEHMKSSEHRLAGSRNKIINGIVQKQDTITEESEKQG 468

Query: 827 SPRRKHSSSSNSQGSIHKSKEDVTVSPSQEINAPPDENKRTPSPGPVESKFLERAGDASA 886
           +   + S+   S+    KS+  +  SP +     P   +R+ SP         R   A  
Sbjct: 469 TKPGRSSTRKRSRSRSPKSRSPIIHSPKRRDRRSPKRRQRSMSPTSTPKAGKIRQSGAKQ 528

Query: 887 PRFNTEQIQYRDSREINAVVTPERRPTSSPRPTSSELLRSHSTDRRVYSRFEPFCKIES 945
                     R+ R        + R     + T  E  +  +      S  EP   +E+
Sbjct: 529 SHMEEFTPPSREDRNAKRSTKQDIRDPRRMKKTEEERPQETTNQHSTKSGTEPKENVEN 587


>gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens]
          Length = 1020

 Score = 43.5 bits (101), Expect = 0.001
 Identities = 53/268 (19%), Positives = 94/268 (35%), Gaps = 14/268 (5%)

Query: 693 VRQPEKPKEDLLKSSKSMHNVTHNLEEDEEEVTKRNSPSGTTTKSVSIAALLDVNKEESN 752
           V+ PEK K    + +KS        +E+ +   K  SP     KS   A      K    
Sbjct: 632 VKSPEKAKSPTKEEAKSPEKAKSPEKEEAKSPEKAKSPVKAEAKSPEKA------KSPVK 685

Query: 753 KELASKKEVKGSPSFLKKGSQKLRSLL---SLTPDKKENLSKNKAPAFYRLCSSSDTLVS 809
            E  S ++ K       K  +K +S +   + +P+K ++  K +A    +  S       
Sbjct: 686 AEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKTPEKAKSPVKEEAK 745

Query: 810 EGEENQKPKKSDTKVDSSPRRKHSSSSNSQGSIHKSKEDVTVSPSQEINAPPDENKRTPS 869
             E+ + P+K+ T    SP  K  +   ++    K  E       +E+ +P         
Sbjct: 746 SPEKAKSPEKAKTLDVKSPEAKTPAKEEARSPADKFPEKAKSPVKEEVKSPEKAKSPLKE 805

Query: 870 PGPVESKFLERAGDASAPRFNTEQIQYRDSREINAVVTPERRPTSSPRPTSSELLRSHST 929
                 K + +  +  +P    E+ Q    +E       E+ P +   P + E  +  S 
Sbjct: 806 DAKAPEKEIPKKEEVKSPVKEEEKPQEVKVKEPPKKAEEEKAPAT---PKTEE--KKDSK 860

Query: 930 DRRVYSRFEPFCKIESSIQPTSNMPNTS 957
                 +  P  K+E   +P    P  S
Sbjct: 861 KEEAPKKEAPKPKVEEKKEPAVEKPKES 888



 Score = 42.0 bits (97), Expect = 0.003
 Identities = 41/189 (21%), Positives = 80/189 (42%), Gaps = 14/189 (7%)

Query: 690 RNRVRQPEKPKEDLLKSSKSMHNVTHNLEEDEEEVTKRNSPSGTTTKSVSIAALLDVNKE 749
           +   + PEK K  + + +K+       ++E+ +   K  SP    T        LDV   
Sbjct: 713 KEEAKSPEKAKSPVKEEAKTPEKAKSPVKEEAKSPEKAKSPEKAKT--------LDVKSP 764

Query: 750 ESNKELASKKEVKGSPSFLKKGSQKLRSLLSLTPDKKENLSKNKAPAFYRLCSSSDTLVS 809
           E+ K  A ++    +  F +K    ++  +  +P+K ++  K  A A  +     + + S
Sbjct: 765 EA-KTPAKEEARSPADKFPEKAKSPVKEEVK-SPEKAKSPLKEDAKAPEKEIPKKEEVKS 822

Query: 810 EGEENQKPKKSDTKVDSSPRRKHSSSSNSQGSIHKSKED-VTVSPSQEINAPPDENKRTP 868
             +E +KP+  + KV   P++     + +     + K+     +P +E   P  E K+ P
Sbjct: 823 PVKEEEKPQ--EVKVKEPPKKAEEEKAPATPKTEEKKDSKKEEAPKKEAPKPKVEEKKEP 880

Query: 869 S-PGPVESK 876
           +   P ESK
Sbjct: 881 AVEKPKESK 889



 Score = 41.6 bits (96), Expect = 0.004
 Identities = 49/234 (20%), Positives = 89/234 (38%), Gaps = 17/234 (7%)

Query: 694 RQPEKPKEDLLKSSKSMHNVTHNLEEDEEEVTKRNSPSGTTTKSVSIAALLDVNKEESNK 753
           + PEK K  + + +KS       ++E+ +   +  SP    + +   A   +  K    +
Sbjct: 599 KSPEKAKSPVKEEAKSPAEAKSPVKEEAKSPAEVKSPEKAKSPTKEEAKSPEKAKSPEKE 658

Query: 754 ELASKKEVKGSPSFLKKGSQKLRSLL---SLTPDKKENLSKNKAPAFYRLCSSSDTLVSE 810
           E  S ++ K       K  +K +S +   + +P+K ++  K +A +  +  S        
Sbjct: 659 EAKSPEKAKSPVKAEAKSPEKAKSPVKAEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKS 718

Query: 811 GEENQKPKKSDTKVD---SSPRRKHSSSSNSQGSIHKSKEDVTVSPSQEINAPPDENKRT 867
            E+ + P K + K      SP ++ + S     S  K+K     SP  E   P  E  R+
Sbjct: 719 PEKAKSPVKEEAKTPEKAKSPVKEEAKSPEKAKSPEKAKTLDVKSP--EAKTPAKEEARS 776

Query: 868 P---------SPGPVESKFLERAGDASAPRFNTEQIQYRDSREINAVVTPERRP 912
           P         SP   E K  E+A           + +     E+ + V  E +P
Sbjct: 777 PADKFPEKAKSPVKEEVKSPEKAKSPLKEDAKAPEKEIPKKEEVKSPVKEEEKP 830



 Score = 34.3 bits (77), Expect = 0.61
 Identities = 63/394 (15%), Positives = 136/394 (34%), Gaps = 44/394 (11%)

Query: 595 LPESIPKLPLQS------EAPKMHTLQVPENHSVALNQTTN------------------- 629
           LPE +PK+P  S         K+  ++  E  +V + + T                    
Sbjct: 422 LPEGLPKIPSVSTHIKVKSEEKIKVVEKSEKETVIVEEQTEETQVTEEVTEEEEKEAKEE 481

Query: 630 -GHTESNNYIYKTLGVNKQTENLKNQQTENLLKRRSFPLFDNSKANLDPGNSKHYVYSTL 688
            G  E      +  G  ++T++   ++  +  K    P+ + +K+  +  + +       
Sbjct: 482 EGKEEEGGEEEEAEGGEEETKSPPAEEAASPEKEAKSPVKEEAKSPAEAKSPEKE--EAK 539

Query: 689 TRNRVRQPEKPKEDLLKSSKSMHNVTHNLEEDEEEVTKRNSPSGTTTKSVSIAALLDVNK 748
           +   V+ PEK K    + +KS        +E+ +   +  SP    + +          K
Sbjct: 540 SPAEVKSPEKAKSPAKEEAKSPPEAKSPEKEEAKSPAEVKSPEKAKSPA----------K 589

Query: 749 EESNKELASKKEVKGSPSFLKKGSQKLRSLLSLTPDKKENLSKNKAPAFYRLCSSSDTLV 808
           EE+ K  A  K  + + S +K+ ++      S   ++ ++ ++ K+P       +     
Sbjct: 590 EEA-KSPAEAKSPEKAKSPVKEEAKSPAEAKSPVKEEAKSPAEVKSPE-----KAKSPTK 643

Query: 809 SEGEENQKPKKSDTKVDSSPRRKHSSSSNSQGSIHKSKEDVTVSPSQEINAPPDENKRTP 868
            E +  +K K  + +   SP +  S       S  K+K  V         A     +   
Sbjct: 644 EEAKSPEKAKSPEKEEAKSPEKAKSPVKAEAKSPEKAKSPVKAEAKSPEKAKSPVKEEAK 703

Query: 869 SPGPVESKFLERAGDASAPRFNTEQIQYRDSREINAVVTPERRPTSSPRPTSSELLRSHS 928
           SP   +S   E A      +   ++      +  + V    + P  +  P  ++ L   S
Sbjct: 704 SPEKAKSPVKEEAKSPEKAKSPVKEEAKTPEKAKSPVKEEAKSPEKAKSPEKAKTLDVKS 763

Query: 929 TDRRVYSRFEPFCKIESSIQPTSNMPNTSINRPE 962
            + +  ++ E     +   +   +     +  PE
Sbjct: 764 PEAKTPAKEEARSPADKFPEKAKSPVKEEVKSPE 797


>gi|22035679 AT rich interactive domain 4B isoform 2 [Homo sapiens]
          Length = 1226

 Score = 43.1 bits (100), Expect = 0.001
 Identities = 66/293 (22%), Positives = 110/293 (37%), Gaps = 53/293 (18%)

Query: 694  RQPEKPKEDLLKSSKSMHNVTHNLEEDEEEVTKRNSPSGTTTKSVSIAALLDVNKEESNK 753
            ++ EK K    K S  M N +++  +++EE TK      T TK  +         EE  K
Sbjct: 755  KKEEKAKN---KESLCMENSSNSSSDEDEEETKAKM---TPTKKYN-------GLEEKRK 801

Query: 754  ELASKKEVKGSPSFLKKGSQKLRSLLSLTPDKKENLSKNKAPAFYRLCSSSDTLVSEGEE 813
             L +         F    S+     + L  +  E L  ++A     + SS         +
Sbjct: 802  SLRTT-------GFYSGFSEVAEKRIKLLNNSDERLQNSRAKDRKDVWSSI--------Q 846

Query: 814  NQKPKK--------SDTKVDSSPRRKHSSSSNSQGSIHKSKEDVTVSPSQEINAPPDENK 865
             Q PKK        SDT+  +SP         ++ S+    E+ + SPS E+  PP  N 
Sbjct: 847  GQWPKKTLKELFSDSDTEAAASPPHPAPEEGVAEESLQTVAEEESCSPSVELEKPPPVNV 906

Query: 866  RTPSPGPVESKFLERAGDASAPRFNTEQIQYRDSREINAVVTPERRPTSSPRPTSSELLR 925
             +    P+E K +E          N  + ++  S   + + TP   P S    T +E  R
Sbjct: 907  DSK---PIEEKTVE---------VNDRKAEFPSSGSNSVLNTPPTTPESPSSVTVTEGSR 954

Query: 926  SHSTDRRVYSRFEPFCKIESSIQPTSNMPNTSINRPEIKSATMG-NSYGRSSP 977
              S+     +  EP    +  ++   +  +++I    +        S G SSP
Sbjct: 955  QQSS----VTVSEPLAPNQEEVRSIKSETDSTIEVDSVAGELQDLQSEGNSSP 1003



 Score = 37.0 bits (84), Expect = 0.094
 Identities = 56/250 (22%), Positives = 101/250 (40%), Gaps = 44/250 (17%)

Query: 594 PLPESIPKLPLQSEAPKMHTLQVPENHSVALNQTTNGHTESNNYIYKT-----LGVNKQT 648
           P PE + KL L ++A    T  +    S+ +    NG   S +    +      G     
Sbjct: 588 PSPEMVSKLDL-TDAKNSDTAHIK---SIEITSILNGLQASESSAEDSEQEDERGAQDMD 643

Query: 649 ENLKNQQTENLLKRRSFPLFDNSKANLDPGNSKHYVYSTLTRNRV--RQPEKPKEDLLKS 706
            N K +   + L      L    + N      ++ V++ L  ++   + PE+ ++D+   
Sbjct: 644 NNGKEESKIDHLTNNRNDLISKEEQNSSSLLEENKVHADLVISKPVSKSPERLRKDI--- 700

Query: 707 SKSMHNVTHNLEEDEEEVTKRNSPSGTTTKSVSIAALLDVNKEESNKELASKKEVKGSPS 766
                 ++ + + +E+EVTK+                 DV K+ ++K  +SK ++K    
Sbjct: 701 ----EVLSEDTDYEEDEVTKKRK---------------DVKKDTTDK--SSKPQIKRGK- 738

Query: 767 FLKKGSQKLRSLLSLTPDKKENLSKNKAPAFYRLC--SSSDTLVSEGEENQKPKKSDTKV 824
             ++       L + +P KKE  +KNK      LC  +SS++   E EE  K K + TK 
Sbjct: 739 --RRYCNTEECLKTGSPGKKEEKAKNKE----SLCMENSSNSSSDEDEEETKAKMTPTKK 792

Query: 825 DSSPRRKHSS 834
            +    K  S
Sbjct: 793 YNGLEEKRKS 802


>gi|22035677 AT rich interactive domain 4B isoform 1 [Homo sapiens]
          Length = 1312

 Score = 43.1 bits (100), Expect = 0.001
 Identities = 66/293 (22%), Positives = 110/293 (37%), Gaps = 53/293 (18%)

Query: 694  RQPEKPKEDLLKSSKSMHNVTHNLEEDEEEVTKRNSPSGTTTKSVSIAALLDVNKEESNK 753
            ++ EK K    K S  M N +++  +++EE TK      T TK  +         EE  K
Sbjct: 841  KKEEKAKN---KESLCMENSSNSSSDEDEEETKAKM---TPTKKYN-------GLEEKRK 887

Query: 754  ELASKKEVKGSPSFLKKGSQKLRSLLSLTPDKKENLSKNKAPAFYRLCSSSDTLVSEGEE 813
             L +         F    S+     + L  +  E L  ++A     + SS         +
Sbjct: 888  SLRTT-------GFYSGFSEVAEKRIKLLNNSDERLQNSRAKDRKDVWSSI--------Q 932

Query: 814  NQKPKK--------SDTKVDSSPRRKHSSSSNSQGSIHKSKEDVTVSPSQEINAPPDENK 865
             Q PKK        SDT+  +SP         ++ S+    E+ + SPS E+  PP  N 
Sbjct: 933  GQWPKKTLKELFSDSDTEAAASPPHPAPEEGVAEESLQTVAEEESCSPSVELEKPPPVNV 992

Query: 866  RTPSPGPVESKFLERAGDASAPRFNTEQIQYRDSREINAVVTPERRPTSSPRPTSSELLR 925
             +    P+E K +E          N  + ++  S   + + TP   P S    T +E  R
Sbjct: 993  DSK---PIEEKTVE---------VNDRKAEFPSSGSNSVLNTPPTTPESPSSVTVTEGSR 1040

Query: 926  SHSTDRRVYSRFEPFCKIESSIQPTSNMPNTSINRPEIKSATMG-NSYGRSSP 977
              S+     +  EP    +  ++   +  +++I    +        S G SSP
Sbjct: 1041 QQSS----VTVSEPLAPNQEEVRSIKSETDSTIEVDSVAGELQDLQSEGNSSP 1089



 Score = 37.0 bits (84), Expect = 0.094
 Identities = 56/250 (22%), Positives = 101/250 (40%), Gaps = 44/250 (17%)

Query: 594 PLPESIPKLPLQSEAPKMHTLQVPENHSVALNQTTNGHTESNNYIYKT-----LGVNKQT 648
           P PE + KL L ++A    T  +    S+ +    NG   S +    +      G     
Sbjct: 674 PSPEMVSKLDL-TDAKNSDTAHIK---SIEITSILNGLQASESSAEDSEQEDERGAQDMD 729

Query: 649 ENLKNQQTENLLKRRSFPLFDNSKANLDPGNSKHYVYSTLTRNRV--RQPEKPKEDLLKS 706
            N K +   + L      L    + N      ++ V++ L  ++   + PE+ ++D+   
Sbjct: 730 NNGKEESKIDHLTNNRNDLISKEEQNSSSLLEENKVHADLVISKPVSKSPERLRKDI--- 786

Query: 707 SKSMHNVTHNLEEDEEEVTKRNSPSGTTTKSVSIAALLDVNKEESNKELASKKEVKGSPS 766
                 ++ + + +E+EVTK+                 DV K+ ++K  +SK ++K    
Sbjct: 787 ----EVLSEDTDYEEDEVTKKRK---------------DVKKDTTDK--SSKPQIKRGK- 824

Query: 767 FLKKGSQKLRSLLSLTPDKKENLSKNKAPAFYRLC--SSSDTLVSEGEENQKPKKSDTKV 824
             ++       L + +P KKE  +KNK      LC  +SS++   E EE  K K + TK 
Sbjct: 825 --RRYCNTEECLKTGSPGKKEEKAKNKE----SLCMENSSNSSSDEDEEETKAKMTPTKK 878

Query: 825 DSSPRRKHSS 834
            +    K  S
Sbjct: 879 YNGLEEKRKS 888


>gi|55741677 SET domain containing 1A [Homo sapiens]
          Length = 1707

 Score = 42.7 bits (99), Expect = 0.002
 Identities = 56/263 (21%), Positives = 90/263 (34%), Gaps = 22/263 (8%)

Query: 726  KRNSPSGTTTKSVSIAALLDVNKEESNKELASKKEVKGSPSFLKKGSQK-----LRSLLS 780
            KR+   G T      +  LD   EE+++E +S+K+ +      +   ++      +    
Sbjct: 943  KRDEERGKTQGKHRKSFALDSEGEEASQESSSEKDEEDDEEDEEDEDREEAVDTTKKETE 1002

Query: 781  LTPDKKENLSKNKAPAFYRLCSSSDTLVSEGEENQKPKKSDTKVDSSPRRKHSSSSNSQG 840
            ++  + E    +   + Y      +   S+ E +     S +   SS     SSSS S  
Sbjct: 1003 VSDGEDEESDSSSKCSLYADSDGENDSTSDSESSSSSSSSSSSSSSSSSSSSSSSSESSS 1062

Query: 841  SIHKSKEDVTVSPSQEINAPPDENKRTPSPGPVESKFLER-AGDASAPRFNTEQIQYR-- 897
               + +E     PS    +PP      P+P PVE    ER AG    P    E    R  
Sbjct: 1063 EDEEEEERPAALPSA---SPPPREVPVPTPAPVEVPVPERVAGSPVTPLPEQEASPARPA 1119

Query: 898  ---DSREINAVVTPERRPTSSP--------RPTSSELLRSHSTDRRVYSRFEPFCKIESS 946
               +    +A + P   P   P        RP+S   L      RR    F     + + 
Sbjct: 1120 GPTEESPPSAPLRPPEPPAGPPAPAPRPDERPSSPIPLLPPPKKRRKTVSFSAIEVVPAP 1179

Query: 947  IQPTSNMPNTSINRPEIKSATMG 969
              P +  P      P  + A  G
Sbjct: 1180 EPPPATPPQAKFPGPASRKAPRG 1202


>gi|217330641 IWS1 homolog [Homo sapiens]
          Length = 819

 Score = 42.7 bits (99), Expect = 0.002
 Identities = 60/291 (20%), Positives = 116/291 (39%), Gaps = 31/291 (10%)

Query: 553 QKEVNSCTTGSSNSTIIGSQGSETPKEVPDTPTNVQHLTDKPLPESIPKLPLQSEAPKMH 612
           + +VN   +GS   ++     +ET       P    H+TD    E +      SE+ ++H
Sbjct: 30  EDDVNEQHSGSDTGSVERHSENETSDREDGLPKG-HHVTDSENDEPLNLNASDSESEELH 88

Query: 613 TLQVPENHSVALNQTTNGHTESNNYIYKTLGVNKQTENLKNQQTENLLKRRSFPLFDNSK 672
             +  ++ S    +     +E+ +       VN+   + ++++T      R  P  D+  
Sbjct: 89  RQKDSDSESEERAEPPASDSENED-------VNQHGSDSESEET------RKLPGSDSEN 135

Query: 673 ANLDPGNSKHYVYSTLTRNRVRQPEKPKEDLLKS----SKSMHNVTHNLEEDEEEVTKRN 728
             L  G++       + ++     E   E+L KS    S++   +   + + E E   R+
Sbjct: 136 EELLNGHASDSENEDVGKHPASDSEI--EELQKSPASDSETEDALKPQISDSESEEPPRH 193

Query: 729 SPSGTTTKSVSIAALLDVNKEESNKELASKKEVKGSPSFLKKGSQKLRSLLSLTPDKKEN 788
             S +  +      + D   EE  K   S  E +  P      S+         P  + +
Sbjct: 194 QASDSENEEPPKPRMSDSESEELPKPQVSDSESEEPPRHQASDSENEE-----LPKPRIS 248

Query: 789 LSKNKAPAFYRLCSSSDTLVSEGEENQKPKKSDTKVDSSPRRKHSSSSNSQ 839
            S+++ P  ++   +SD   SE EE  KP+ SD++ +  PR + S S N +
Sbjct: 249 DSESEDPPRHQ---ASD---SENEELPKPRISDSESEDPPRNQASDSENEE 293



 Score = 41.2 bits (95), Expect = 0.005
 Identities = 54/240 (22%), Positives = 100/240 (41%), Gaps = 20/240 (8%)

Query: 641 TLGVNKQTENLKNQQTENLLKRRSFPLFDNSKA-NLDPGNSKHYVYSTLTRNRVRQPEKP 699
           T  V + +EN  + + + L K       +N +  NL+  +S+      L R +    E  
Sbjct: 42  TGSVERHSENETSDREDGLPKGHHVTDSENDEPLNLNASDSES---EELHRQKDSDSESE 98

Query: 700 KEDLLKSSKSMH-NVTHNLEEDEEEVTKRNSPSGTTTKSVSIAALLDVNKEESNKELASK 758
           +     +S S + +V  +  + E E T++   S +  + +      D   E+  K  AS 
Sbjct: 99  ERAEPPASDSENEDVNQHGSDSESEETRKLPGSDSENEELLNGHASDSENEDVGKHPASD 158

Query: 759 KEVKG---SPSFLKKGSQKLRSLLSLT-----PDKKENLSKNKAPAFYRLCSSSDTLVSE 810
            E++    SP+   +    L+  +S +     P  + + S+N+ P   R+  S      E
Sbjct: 159 SEIEELQKSPASDSETEDALKPQISDSESEEPPRHQASDSENEEPPKPRMSDS------E 212

Query: 811 GEENQKPKKSDTKVDSSPRRKHSSSSNSQGSIHKSKEDVTVSPSQEINAPPDENKRTPSP 870
            EE  KP+ SD++ +  PR + S S N +    +  +  +  P +   A   EN+  P P
Sbjct: 213 SEELPKPQVSDSESEEPPRHQASDSENEELPKPRISDSESEDPPRH-QASDSENEELPKP 271


>gi|150378545 POM121 membrane glycoprotein (rat)-like [Homo sapiens]
          Length = 987

 Score = 42.4 bits (98), Expect = 0.002
 Identities = 61/255 (23%), Positives = 104/255 (40%), Gaps = 27/255 (10%)

Query: 669 DNSKANLDPGNSKHYVYSTLTRNRVRQPEKPKEDLLKSSKSMHNVTHNLEEDEEEVTKRN 728
           +N +   D   S H  +  L  + V     PK   LK   +  +   +L +     +  +
Sbjct: 72  ENKRRRHDSSGSGHSAFEPLVASGVPASFVPKPGSLKRGLNSQSSDDHLNKRSRS-SSMS 130

Query: 729 SPSGTTTKSVSIAALLDVNKEESNKELASKKEVKGSPSFLKKGSQKLRSLLSLTPDKKEN 788
           S +G  T  +  ++   +    S+    S+   +  PS     S    S  S TP++   
Sbjct: 131 SLTGAYTSGIPSSSRNAITSSYSSTRGISQLWKRNGPSSSPFSSPA--SSRSQTPERPAK 188

Query: 789 LSKNKAPAFYRLC--SSSDTLVSEGEENQKPKKSDTKVDSSPRRKHSSSSNS-QGSIHKS 845
             + +      LC  SSS T ++  +E+Q  K +DT    +PR+K +S+S S  GS  + 
Sbjct: 189 KIREE-----ELCHHSSSSTPLAADKESQGEKAADT----TPRKKQNSNSQSTPGSSGQR 239

Query: 846 KEDVTVSPS---QEINAPPDENKRTPSPG-PVESKFLERAGDASAPRFNTEQIQYRDSRE 901
           K  V + PS   +++  PP      P  G  + ++ L+    AS   FN       D+  
Sbjct: 240 KRKVQLLPSRRGEQLTLPP-----PPQLGYSITAEDLDLEKKASLQWFNQALEDKSDAAS 294

Query: 902 INAVVTPERRPTSSP 916
            +   TP   PT+ P
Sbjct: 295 NSVTETP---PTTQP 306


>gi|84043963 eukaryotic translation initiation factor 5B [Homo
           sapiens]
          Length = 1220

 Score = 42.0 bits (97), Expect = 0.003
 Identities = 56/277 (20%), Positives = 105/277 (37%), Gaps = 38/277 (13%)

Query: 646 KQTENLKNQQTENLLKRRSFPLFDN----SKANLDPGNSKHYVYSTLTRNRVRQPEKPKE 701
           K+ E L+  + +   ++ S   F+     SK  +D G          +  +   P   ++
Sbjct: 254 KEKEELETGKKDQSKQKESQRKFEEETVKSKVTVDTG------VIPASEEKAETPTAAED 307

Query: 702 DLLKSSKSMHNVTHNLEEDEEEVTKRNSPSGTTTKSVSIAALLDVNKEESNKELASKKEV 761
           D     K         E++E+E  K+  PS  T K++   AL  + +EE  ++   ++ +
Sbjct: 308 DNEGDKKKKDKKKKKGEKEEKEKEKKKGPSKATVKAMQ-EALAKLKEEEERQKREEEERI 366

Query: 762 KGSPSFLKKGSQKLRSLLSLTPDKKENLSKNKAPAFYRLCSSSDTLVSEGEENQKPKKSD 821
           K       K  ++ R    L  +K+E   + +     RL      L     E +   ++ 
Sbjct: 367 KRLEELEAKRKEEER----LEQEKRERKKQKEKERKERLKKEGKLLTKSQREARARAEAT 422

Query: 822 TKV-----------DSSPRRKHSSSSNSQGSIHKSKEDVTVSPSQEINAP--------PD 862
            K+           DS P+++       +  I +  E   VS S E+ A         P+
Sbjct: 423 LKLLQAQGVEVPSKDSLPKKRPIYEDKKRKKIPQQLESKEVSESMELCAAVEVMEQGVPE 482

Query: 863 ENKRTPSPGPVESKFLERAG----DASAPRFNTEQIQ 895
           + +  P   P E +  E AG    +A A    TE+++
Sbjct: 483 KEETPPPVEPEEEEDTEDAGLDDWEAMASDEETEKVE 519


>gi|5729790 CCCTC-binding factor [Homo sapiens]
          Length = 727

 Score = 41.6 bits (96), Expect = 0.004
 Identities = 33/136 (24%), Positives = 59/136 (43%), Gaps = 8/136 (5%)

Query: 801 CSSSDTLVSE-GEENQKPKKSDTKVDSSPRRKHSSSSNSQGSIHKSKEDVTVSPSQEINA 859
           C+  D +  E G E +K K+   +   S +   S S N++  +  ++++    P+ EI  
Sbjct: 577 CAGPDGVEGENGGETKKSKRGRKRKMRSKKEDSSDSENAEPDLDDNEDEE--EPAVEIEP 634

Query: 860 PPDENKRTPSPGPVESKFLERAGDASAPRFN--TEQIQYRDSRE---INAVVTPERRPTS 914
            P+    TP+P P + +     G  + P+ N  T  IQ  D       N +V  ++ P +
Sbjct: 635 EPEPQPVTPAPPPAKKRRGRPPGRTNQPKQNQPTAIIQVEDQNTGAIENIIVEVKKEPDA 694

Query: 915 SPRPTSSELLRSHSTD 930
            P     E  +  +TD
Sbjct: 695 EPAEGEEEEAQPAATD 710


>gi|239754624 PREDICTED: similar to hCG1998564 [Homo sapiens]
          Length = 526

 Score = 41.6 bits (96), Expect = 0.004
 Identities = 66/288 (22%), Positives = 112/288 (38%), Gaps = 54/288 (18%)

Query: 669 DNSKANLDPGNSKHYVYSTLTRNRVRQPEKPKEDLLKSSKSMHNVTHNLEEDEEEVTKRN 728
           +N +   D   S H  +  L  N V     PK   LK          N +  ++ + KR+
Sbjct: 200 ENKRRRHDSSGSGHSAFEPLVANGVPASFVPKPGSLKRGL-------NSQSSDDHLNKRS 252

Query: 729 SPSGTTTKSVSIAALLDVNKEESNKELASKKEVKGSPSFLKKGSQKLR------SLLSLT 782
             S  ++ + + A+   +     N   +S    +G     K+            S  S T
Sbjct: 253 RSSSMSSLTGAYAS--GIPSSSRNAITSSYSSTRGISQLWKRNGPSSSPFSSPASSRSQT 310

Query: 783 PDKKENLSKNKAPAFYRLC--SSSDTLVSEGEENQKPKKSDTKVDSSPRRKHSSSSNS-Q 839
           P++     + +      LC  SSS T ++   E+Q  K +DT    +PR+K +S+S S  
Sbjct: 311 PERPAKKIREE-----ELCHHSSSSTPLAADRESQGEKAADT----TPRKKQNSNSQSTP 361

Query: 840 GSIHKSKEDVTVSPS---QEINAPPDENKRTPSPG-PVESKFLERAGDASAPRFNTEQIQ 895
           GS  + K  V + PS   +++  PP      P  G  + ++ L+    AS   FN + ++
Sbjct: 362 GSSGQRKRKVQLLPSRRGEQLTLPP-----PPQLGYSITAEDLDLEKKASLQWFN-QALE 415

Query: 896 YRDSREINAV-----------------VTPERRPTSSPRPTSSELLRS 926
            +     N+V                   P   PTS   P+++ LL S
Sbjct: 416 DKSDAASNSVTETPPITQPSFTFTLPAAAPASPPTSLLAPSTNPLLES 463


>gi|26051278 nuclear pore membrane protein 121 [Homo sapiens]
          Length = 984

 Score = 41.6 bits (96), Expect = 0.004
 Identities = 66/288 (22%), Positives = 112/288 (38%), Gaps = 54/288 (18%)

Query: 669 DNSKANLDPGNSKHYVYSTLTRNRVRQPEKPKEDLLKSSKSMHNVTHNLEEDEEEVTKRN 728
           +N +   D   S H  +  L  N V     PK   LK          N +  ++ + KR+
Sbjct: 72  ENKRRRHDSSGSGHSAFEPLVANGVPASFVPKPGSLKRGL-------NSQSSDDHLNKRS 124

Query: 729 SPSGTTTKSVSIAALLDVNKEESNKELASKKEVKGSPSFLKKGSQKLR------SLLSLT 782
             S  ++ + + A+   +     N   +S    +G     K+            S  S T
Sbjct: 125 RSSSMSSLTGAYAS--GIPSSSRNAITSSYSSTRGISQLWKRNGPSSSPFSSPASSRSQT 182

Query: 783 PDKKENLSKNKAPAFYRLC--SSSDTLVSEGEENQKPKKSDTKVDSSPRRKHSSSSNS-Q 839
           P++     + +      LC  SSS T ++   E+Q  K +DT    +PR+K +S+S S  
Sbjct: 183 PERPAKKIREE-----ELCHHSSSSTPLAADRESQGEKAADT----TPRKKQNSNSQSTP 233

Query: 840 GSIHKSKEDVTVSPS---QEINAPPDENKRTPSPG-PVESKFLERAGDASAPRFNTEQIQ 895
           GS  + K  V + PS   +++  PP      P  G  + ++ L+    AS   FN + ++
Sbjct: 234 GSSGQRKRKVQLLPSRRGEQLTLPP-----PPQLGYSITAEDLDLEKKASLQWFN-QALE 287

Query: 896 YRDSREINAV-----------------VTPERRPTSSPRPTSSELLRS 926
            +     N+V                   P   PTS   P+++ LL S
Sbjct: 288 DKSDAASNSVTETPPITQPSFTFTLPAAAPASPPTSLLAPSTNPLLES 335


>gi|89276756 serine/threonine-protein kinase PRP4K [Homo sapiens]
          Length = 1007

 Score = 41.2 bits (95), Expect = 0.005
 Identities = 80/357 (22%), Positives = 136/357 (38%), Gaps = 49/357 (13%)

Query: 647 QTENLKNQ-QTENLLKRRSFPLFDNSKANLDPGNSKHYVYSTLTRNRVRQPEKPK----E 701
           +T++L+ Q + E+    +S    +N + + D   +KH  +         + +K K    E
Sbjct: 5   ETQSLREQPEMEDANSEKSINE-ENGEVSEDQSQNKHSRHKKKKHKHRSKHKKHKHSSEE 63

Query: 702 DLLKSSKSMH-NVTHNLEEDEEEVTKRNSPSGTTTKSVSIAALLDVNKE------ESNKE 754
           D  K  K  H +  H  +E  +   K        TK   +A L D+ K+      E + E
Sbjct: 64  DKDKKHKHKHKHKKHKRKEIIDASDKEGMSPAKRTKLDDLALLEDLEKQRALIKAELDNE 123

Query: 755 LASKKEVKGSPSFLK---KGSQKLRSLLSLTPDKKENLSKNKAPAFYRLCSSSDTLVSEG 811
           L   K   G    L+    GS++   +     +K  N +++         SSS     E 
Sbjct: 124 LMEGKVQSGMGLILQGYESGSEEEGEI----HEKARNGNRSSTR------SSSTKGKLEL 173

Query: 812 EENQKPKKSDTKVDSSPRRKH-SSSSNSQGSIHKSKEDVTVSPSQEINAPPDENKRTPSP 870
            +N+   K  +K  S  R +H S    S+G I   KE  T S S+E       +KR+ S 
Sbjct: 174 VDNKITTKKRSKSRSKERTRHRSDKKKSKGGIEIVKEKTTRSKSKERKKSKSPSKRSKSQ 233

Query: 871 G--------PVESKFLERAGDASAPRFNTEQIQYRD---SREINAVVTPERRPTSSPRPT 919
                     +  +  E+ G A +P  +  +I+ +     R+ + ++   R      +  
Sbjct: 234 DQARKSKSPTLRRRSQEKIGKARSPTDDKVKIEDKSKSKDRKKSPIINESRSRDRGKKSR 293

Query: 920 SSELLRSHSTDRRVYSRFEPFCKIESSIQPTSNMPNTSINRPEIKSATMGNSYGRSS 976
           S   LR  S DRR  S+           +  S    T   +  IKS +   S G+ +
Sbjct: 294 SPVDLRGKSKDRRSRSK-----------ERKSKRSETDKEKKPIKSPSKDASSGKEN 339



 Score = 40.4 bits (93), Expect = 0.008
 Identities = 52/248 (20%), Positives = 96/248 (38%), Gaps = 36/248 (14%)

Query: 689 TRNRVRQPEKPKEDLLKSSKSMHNVTHNLEEDEEEVTKRNSPSGTTTKSVSIAALLDVNK 748
           +++R ++  + + D  KS   +  V       +E+ T+  S     +KS S        K
Sbjct: 184 SKSRSKERTRHRSDKKKSKGGIEIV-------KEKTTRSKSKERKKSKSPS--------K 228

Query: 749 EESNKELASKKEVKGSPSFLKKGSQKLRSLLSLTPDKKENLSKNKAPAFYRLCSSSDTLV 808
              +++ A K +   SP+  ++  +K+    S T DK +   K+K+            ++
Sbjct: 229 RSKSQDQARKSK---SPTLRRRSQEKIGKARSPTDDKVKIEDKSKSKD-----RKKSPII 280

Query: 809 SEGEENQKPKKSDTKVDSSPRRKHSSSSNSQGSIHKSKEDVTVSPSQEINAPPDENKRTP 868
           +E     + KKS + VD   + K   S + +    +S+ D    P +  +      K   
Sbjct: 281 NESRSRDRGKKSRSPVDLRGKSKDRRSRSKERKSKRSETDKEKKPIKSPSKDASSGKENR 340

Query: 869 SPGPVESKFLERAGDASAPRFNTEQIQYRDSREINAVVTPERRPTSSPRPTSSELLRSHS 928
           SP     +  +R   +  PR          SR   + +  +RR   S  P+     R+ S
Sbjct: 341 SPSRRPGRSPKRRSLSPKPR--------DKSRRSRSPLLNDRRSKQSKSPS-----RTLS 387

Query: 929 TDRRVYSR 936
             RR  SR
Sbjct: 388 PGRRAKSR 395


>gi|104526627 triadin [Homo sapiens]
          Length = 729

 Score = 40.0 bits (92), Expect = 0.011
 Identities = 49/190 (25%), Positives = 86/190 (45%), Gaps = 22/190 (11%)

Query: 717 LEEDEEEVTKRNSPSGTTTKSVSIAALLDVNKEESNKELASKKEVK--GSPSFLKKGSQK 774
           LEE E E  K      + TK      +    K++S KE A   E K  G  S  K+G+ K
Sbjct: 309 LEEKEGEKKKAEKKVTSETKKKEKEDI----KKKSEKETAIDVEKKEPGKASETKQGTVK 364

Query: 775 LRSLLSLTPD-KKENLSKNKAPAFYRLCSSSDTLVSEGEENQKPKKSDTKVDSSPRRKHS 833
           + +  +   D KKE+  K K PA        +    +G++ +K K+   +   SP+++HS
Sbjct: 365 IAAQAAAKKDEKKEDSKKTKKPA--------EVEQPKGKKQEK-KEKHVEPAKSPKKEHS 415

Query: 834 SSSNSQ--GSIHKSKEDVTVSPSQEINAPPDENKRTPSPGPVESKF-LERAGDASAPRFN 890
             S+ Q      ++KE++     ++      E K T +   VE +   E++G  S+   +
Sbjct: 416 VPSDKQVKAKTERAKEEIGAVSIKKAVPGKKEEKTTKT---VEQEIRKEKSGKTSSILKD 472

Query: 891 TEQIQYRDSR 900
            E I+ ++ +
Sbjct: 473 KEPIKGKEEK 482



 Score = 36.2 bits (82), Expect = 0.16
 Identities = 43/209 (20%), Positives = 81/209 (38%), Gaps = 29/209 (13%)

Query: 690 RNRVRQPEKPK-EDLLKSSKSMHNVTHNLEEDEEEVT--KRNSPSGTTTKSVSIAALLDV 746
           + ++ + EKP+ + L K  K       + E+ ++EV   K+     T  K   +      
Sbjct: 187 KEKIEKKEKPETKTLAKEQKKAKTAEKSEEKTKKEVKGGKQEKVKQTAAKVKEVQKTPSK 246

Query: 747 NKEESNKELA--SKKEVKGSPSFLK-------KGSQKLRSLLSLTPDKKENLSKNKAPAF 797
            KE+ +KE A  SK E K   +F +        G  K     ++ P      +    PA 
Sbjct: 247 PKEKEDKEKAAVSKHEQKDQYAFCRYMIDIFVHGDLKPGQSPAIPPPLPTEQASRPTPAS 306

Query: 798 YRLCS------------SSDTLVSEGEENQKPKKSDTKVDSSPRRKHSSSSNSQGSIHKS 845
             L              +S+T   E E+ +K  + +T +D   +    +S   QG++   
Sbjct: 307 PALEEKEGEKKKAEKKVTSETKKKEKEDIKKKSEKETAIDVEKKEPGKASETKQGTV--- 363

Query: 846 KEDVTVSPSQEINAPPDENKRTPSPGPVE 874
              +    + + +   +++K+T  P  VE
Sbjct: 364 --KIAAQAAAKKDEKKEDSKKTKKPAEVE 390


>gi|38146107 arginine/serine-rich coiled-coil 2 isoform a [Homo
           sapiens]
          Length = 434

 Score = 40.0 bits (92), Expect = 0.011
 Identities = 46/257 (17%), Positives = 99/257 (38%), Gaps = 5/257 (1%)

Query: 669 DNSKANLDPGNSKHYVYSTLTRNRVRQPEKPKEDLLKSSKSMHNVTHNLEEDEEEVTKRN 728
           + S+ ++ P  SKH+   + +R+R R+ +   E     S+S        E  ++   K  
Sbjct: 25  EQSEVSVSPRASKHHYSRSRSRSRERKRKSDNEGRKHRSRSRSKEGRRHESKDKSSKKHK 84

Query: 729 SPSGTTTKSVSIAALLDVNKEESNKELASKKEVKGSPSFLKKGSQ-KLRSLLSLTPDKKE 787
           S      +  S      +N  E+ ++   +KE K S       S+ + R   S + ++K+
Sbjct: 85  SEEHNDKEHSSDKGRERLNSSENGEDRHKRKERKSSRGRSHSRSRSRERRHRSRSRERKK 144

Query: 788 NLSKNKAPAFYRLCSSSDTLVSEGEENQKPKKSDTKVDSSPRRKHSSSSNSQGSIHKSKE 847
           + S+++     R   S +   S     ++ ++  ++  S  R +H + S S+        
Sbjct: 145 SRSRSRERKKSR-SRSRERKKSRSRSRERKRRIRSRSRSRSRHRHRTRSRSRTRSRSRDR 203

Query: 848 DVTVSPSQEINAPPDENKRTPSPGPVESKFLERAGDASAPRFNTEQIQYRDSREINAVVT 907
              +   +  +       RTPSP P   +        +  R      + ++ RE   V  
Sbjct: 204 KKRIEKPRRFSR---SLSRTPSPPPFRGRNTAMDAQEALARRLERAKKLQEQREKEMVEK 260

Query: 908 PERRPTSSPRPTSSELL 924
            +++  ++   T   +L
Sbjct: 261 QKQQEIAAAAATGGSVL 277


>gi|4758172 dentin matrix acidic phosphoprotein 1 isoform 1
           precursor [Homo sapiens]
          Length = 513

 Score = 39.7 bits (91), Expect = 0.014
 Identities = 60/257 (23%), Positives = 99/257 (38%), Gaps = 44/257 (17%)

Query: 629 NGHTESNNYIYKTLGVNKQTENLKNQQTENLLKRRSFPLF-------DNSKANLDPGNSK 681
           N    S     K  G N +  N ++     LL+  S  +F       ++ ++ LD  N+ 
Sbjct: 229 NSRMNSAGMKSKESGENSEQANTQDSGGSQLLEHPSRKIFRKSRISEEDDRSELDDNNTM 288

Query: 682 HYVYSTLTRNR------VRQP---------EKPKEDLLK---------SSKSMHNVT--- 714
             V S  T N       + QP         E  KE+L +         SS+S        
Sbjct: 289 EEVKSDSTENSNSRDTGLSQPRRDSKGDSQEDSKENLSQEESQNVDGPSSESSQEANLSS 348

Query: 715 -HNLEEDEEEVTK--RNSPSGTTTKSVSIAALLDVNKEESNKELASKKEVKGSPSFLKKG 771
             N  E +EEV    R      TT  V      D ++E+S+  L+  K    S S  ++ 
Sbjct: 349 QENSSESQEEVVSESRGDNPDPTTSYVEDQEDSDSSEEDSSHTLSHSK----SESREEQA 404

Query: 772 SQKLRSLLSLTPDKKENLSKNKAPAFYRLCSSSDTLVSEGEENQKPKKSDTKVDSSPRRK 831
             +    L+ + +  E+     + +   L S S +  S+ EE+   +      DSS  ++
Sbjct: 405 DSESSESLNFSEESPESPEDENSSSQEGLQSHSSSAESQSEESHSEEDDSDSQDSSRSKE 464

Query: 832 HSSSSNSQGSIHKSKED 848
            S+S+ S+ S   S+ED
Sbjct: 465 DSNSTESKSS---SEED 478


>gi|121256621 dentin matrix acidic phosphoprotein 1 isoform 2
           precursor [Homo sapiens]
          Length = 497

 Score = 39.7 bits (91), Expect = 0.014
 Identities = 60/257 (23%), Positives = 99/257 (38%), Gaps = 44/257 (17%)

Query: 629 NGHTESNNYIYKTLGVNKQTENLKNQQTENLLKRRSFPLF-------DNSKANLDPGNSK 681
           N    S     K  G N +  N ++     LL+  S  +F       ++ ++ LD  N+ 
Sbjct: 213 NSRMNSAGMKSKESGENSEQANTQDSGGSQLLEHPSRKIFRKSRISEEDDRSELDDNNTM 272

Query: 682 HYVYSTLTRNR------VRQP---------EKPKEDLLK---------SSKSMHNVT--- 714
             V S  T N       + QP         E  KE+L +         SS+S        
Sbjct: 273 EEVKSDSTENSNSRDTGLSQPRRDSKGDSQEDSKENLSQEESQNVDGPSSESSQEANLSS 332

Query: 715 -HNLEEDEEEVTK--RNSPSGTTTKSVSIAALLDVNKEESNKELASKKEVKGSPSFLKKG 771
             N  E +EEV    R      TT  V      D ++E+S+  L+  K    S S  ++ 
Sbjct: 333 QENSSESQEEVVSESRGDNPDPTTSYVEDQEDSDSSEEDSSHTLSHSK----SESREEQA 388

Query: 772 SQKLRSLLSLTPDKKENLSKNKAPAFYRLCSSSDTLVSEGEENQKPKKSDTKVDSSPRRK 831
             +    L+ + +  E+     + +   L S S +  S+ EE+   +      DSS  ++
Sbjct: 389 DSESSESLNFSEESPESPEDENSSSQEGLQSHSSSAESQSEESHSEEDDSDSQDSSRSKE 448

Query: 832 HSSSSNSQGSIHKSKED 848
            S+S+ S+ S   S+ED
Sbjct: 449 DSNSTESKSS---SEED 462


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.311    0.127    0.365 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 40,308,543
Number of Sequences: 37866
Number of extensions: 1943533
Number of successful extensions: 7152
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 21
Number of HSP's successfully gapped in prelim test: 342
Number of HSP's that attempted gapping in prelim test: 6462
Number of HSP's gapped (non-prelim): 837
length of query: 1011
length of database: 18,247,518
effective HSP length: 112
effective length of query: 899
effective length of database: 14,006,526
effective search space: 12591866874
effective search space used: 12591866874
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 67 (30.4 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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