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Search of human proteins with 60097902
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|60097902 filaggrin [Homo sapiens]
(4061 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|60097902 filaggrin [Homo sapiens] 8232 0.0
gi|57864582 hornerin [Homo sapiens] 882 0.0
gi|62122917 filaggrin family member 2 [Homo sapiens] 756 0.0
gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens] 263 2e-69
gi|239743293 PREDICTED: mucin 12 [Homo sapiens] 219 3e-56
gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens] 183 3e-45
gi|171916097 repetin [Homo sapiens] 175 9e-43
gi|223890219 RNA binding motif protein, X-linked-like 3 [Homo sa... 145 1e-33
gi|148746195 trichohyalin [Homo sapiens] 122 9e-27
gi|6631100 natural killer-tumor recognition sequence [Homo sapiens] 120 3e-26
gi|239508976 PREDICTED: mucin 12, cell surface associated [Homo ... 114 2e-24
gi|116008442 zinc finger CCCH-type containing 13 [Homo sapiens] 110 2e-23
gi|7706635 cornulin [Homo sapiens] 103 5e-21
gi|239758013 PREDICTED: hypothetical protein [Homo sapiens] 100 3e-20
gi|50962882 G patch domain containing 8 [Homo sapiens] 99 1e-19
gi|224548936 hypothetical protein LOC100170229 [Homo sapiens] 98 1e-19
gi|153251865 hypothetical protein LOC84226 [Homo sapiens] 96 7e-19
gi|4504487 histidine rich calcium binding protein precursor [Hom... 95 2e-18
gi|4758172 dentin matrix acidic phosphoprotein 1 isoform 1 precu... 92 1e-17
gi|161016767 mucin 21 [Homo sapiens] 91 3e-17
gi|56606114 trichohyalin-like 1 [Homo sapiens] 91 3e-17
gi|117414137 retinitis pigmentosa 1-like 1 [Homo sapiens] 90 5e-17
gi|50083281 KIAA1853 protein [Homo sapiens] 90 5e-17
gi|239754668 PREDICTED: mucin 12 [Homo sapiens] 88 2e-16
gi|78190492 retinitis pigmentosa GTPase regulator isoform C [Hom... 87 3e-16
gi|158854042 hypothetical protein LOC222183 [Homo sapiens] 87 3e-16
gi|28559039 mediator complex subunit 1 [Homo sapiens] 86 7e-16
gi|7656879 ALL1 fused gene from 5q31 [Homo sapiens] 84 2e-15
gi|207113162 Treacher Collins-Franceschetti syndrome 1 isoform e... 84 3e-15
gi|21361282 splicing factor, arginine/serine-rich 4 [Homo sapiens] 82 8e-15
>gi|60097902 filaggrin [Homo sapiens]
Length = 4061
Score = 8232 bits (21359), Expect = 0.0
Identities = 4061/4061 (100%), Positives = 4061/4061 (100%)
Query: 1 MSTLLENIFAIINLFKQYSKKDKNTDTLSKKELKELLEKEFRQILKNPDDPDMVDVFMDH 60
MSTLLENIFAIINLFKQYSKKDKNTDTLSKKELKELLEKEFRQILKNPDDPDMVDVFMDH
Sbjct: 1 MSTLLENIFAIINLFKQYSKKDKNTDTLSKKELKELLEKEFRQILKNPDDPDMVDVFMDH 60
Query: 61 LDIDHNKKIDFTEFLLMVFKLAQAYYESTRKENLPISGHKHRKHSHHDKHEDNKQEENKE 120
LDIDHNKKIDFTEFLLMVFKLAQAYYESTRKENLPISGHKHRKHSHHDKHEDNKQEENKE
Sbjct: 61 LDIDHNKKIDFTEFLLMVFKLAQAYYESTRKENLPISGHKHRKHSHHDKHEDNKQEENKE 120
Query: 121 NRKRPSSLERRNNRKGNKGRSKSPRETGGKRHESSSEKKERKGYSPTHREEEYGKNHHNS 180
NRKRPSSLERRNNRKGNKGRSKSPRETGGKRHESSSEKKERKGYSPTHREEEYGKNHHNS
Sbjct: 121 NRKRPSSLERRNNRKGNKGRSKSPRETGGKRHESSSEKKERKGYSPTHREEEYGKNHHNS 180
Query: 181 SKKEKNKTENTRLGDNRKRLSERLEEKEDNEEGVYDYENTGRMTQKWIQSGHIATYYTIQ 240
SKKEKNKTENTRLGDNRKRLSERLEEKEDNEEGVYDYENTGRMTQKWIQSGHIATYYTIQ
Sbjct: 181 SKKEKNKTENTRLGDNRKRLSERLEEKEDNEEGVYDYENTGRMTQKWIQSGHIATYYTIQ 240
Query: 241 DEAYDTTDSLLEENKIYERSRSSDGKSSSQVNRSRHENTSQVPLQESRTRKRRGSRVSQD 300
DEAYDTTDSLLEENKIYERSRSSDGKSSSQVNRSRHENTSQVPLQESRTRKRRGSRVSQD
Sbjct: 241 DEAYDTTDSLLEENKIYERSRSSDGKSSSQVNRSRHENTSQVPLQESRTRKRRGSRVSQD 300
Query: 301 RDSEGHSEDSERHSGSASRNHHGSAWEQSRDGSRHPRSHDEDRASHGHSADSSRQSGTRH 360
RDSEGHSEDSERHSGSASRNHHGSAWEQSRDGSRHPRSHDEDRASHGHSADSSRQSGTRH
Sbjct: 301 RDSEGHSEDSERHSGSASRNHHGSAWEQSRDGSRHPRSHDEDRASHGHSADSSRQSGTRH 360
Query: 361 AETSSRGQTASSHEQARSSPGERHGSGHQQSADSSRHSATGRGQASSAVSDRGHRGSSGS 420
AETSSRGQTASSHEQARSSPGERHGSGHQQSADSSRHSATGRGQASSAVSDRGHRGSSGS
Sbjct: 361 AETSSRGQTASSHEQARSSPGERHGSGHQQSADSSRHSATGRGQASSAVSDRGHRGSSGS 420
Query: 421 QASDSEGHSENSDTQSVSGHGKAGLRQQSHQESTRGRSGERSGRSGSSLYQVSTHEQPDS 480
QASDSEGHSENSDTQSVSGHGKAGLRQQSHQESTRGRSGERSGRSGSSLYQVSTHEQPDS
Sbjct: 421 QASDSEGHSENSDTQSVSGHGKAGLRQQSHQESTRGRSGERSGRSGSSLYQVSTHEQPDS 480
Query: 481 AHGRTGTSTGGRQGSHHEQARDSSRHSASQEGQDTIRGHPGSSRGGRQGSHHEQSVNRSG 540
AHGRTGTSTGGRQGSHHEQARDSSRHSASQEGQDTIRGHPGSSRGGRQGSHHEQSVNRSG
Sbjct: 481 AHGRTGTSTGGRQGSHHEQARDSSRHSASQEGQDTIRGHPGSSRGGRQGSHHEQSVNRSG 540
Query: 541 HSGSHHSHTTSQGRSDASHGQSGSRSASRQTRNEEQSGDGTRHSGSRHHEASSQADSSRH 600
HSGSHHSHTTSQGRSDASHGQSGSRSASRQTRNEEQSGDGTRHSGSRHHEASSQADSSRH
Sbjct: 541 HSGSHHSHTTSQGRSDASHGQSGSRSASRQTRNEEQSGDGTRHSGSRHHEASSQADSSRH 600
Query: 601 SQVGQGQSSGPRTSRNQGSSVSQDSDSQGHSEDSERWSGSASRNHHGSAQEQSRDGSRHP 660
SQVGQGQSSGPRTSRNQGSSVSQDSDSQGHSEDSERWSGSASRNHHGSAQEQSRDGSRHP
Sbjct: 601 SQVGQGQSSGPRTSRNQGSSVSQDSDSQGHSEDSERWSGSASRNHHGSAQEQSRDGSRHP 660
Query: 661 RSHHEDRAGHGHSADSSRKSGTRHTQNSSSGQAASSHEQARSSAGERHGSRHQLQSADSS 720
RSHHEDRAGHGHSADSSRKSGTRHTQNSSSGQAASSHEQARSSAGERHGSRHQLQSADSS
Sbjct: 661 RSHHEDRAGHGHSADSSRKSGTRHTQNSSSGQAASSHEQARSSAGERHGSRHQLQSADSS 720
Query: 721 RHSGTGHGQASSAVRDSGHRGSSGSQATDSEGHSEDSDTQSVSGHGQAGHHQQSHQESAR 780
RHSGTGHGQASSAVRDSGHRGSSGSQATDSEGHSEDSDTQSVSGHGQAGHHQQSHQESAR
Sbjct: 721 RHSGTGHGQASSAVRDSGHRGSSGSQATDSEGHSEDSDTQSVSGHGQAGHHQQSHQESAR 780
Query: 781 DRSGERSRRSGSFLYQVSTHKQSESSHGWTGPSTGVRQGSHHEQARDNSRHSASQDGQDT 840
DRSGERSRRSGSFLYQVSTHKQSESSHGWTGPSTGVRQGSHHEQARDNSRHSASQDGQDT
Sbjct: 781 DRSGERSRRSGSFLYQVSTHKQSESSHGWTGPSTGVRQGSHHEQARDNSRHSASQDGQDT 840
Query: 841 IRGHPGSSRRGRQGSHHEQSVDRSGHSGSHHSHTTSQGRSDASRGQSGSRSASRTTRNEE 900
IRGHPGSSRRGRQGSHHEQSVDRSGHSGSHHSHTTSQGRSDASRGQSGSRSASRTTRNEE
Sbjct: 841 IRGHPGSSRRGRQGSHHEQSVDRSGHSGSHHSHTTSQGRSDASRGQSGSRSASRTTRNEE 900
Query: 901 QSRDGSRHSGSRHHEASSHADISRHSQAGQGQSEGSRTSRRQGSSVSQDSDSEGHSEDSE 960
QSRDGSRHSGSRHHEASSHADISRHSQAGQGQSEGSRTSRRQGSSVSQDSDSEGHSEDSE
Sbjct: 901 QSRDGSRHSGSRHHEASSHADISRHSQAGQGQSEGSRTSRRQGSSVSQDSDSEGHSEDSE 960
Query: 961 RWSGSASRNHRGSAQEQSRHGSRHPRSHHEDRAGHGHSADSSRQSGTPHAETSSGGQAAS 1020
RWSGSASRNHRGSAQEQSRHGSRHPRSHHEDRAGHGHSADSSRQSGTPHAETSSGGQAAS
Sbjct: 961 RWSGSASRNHRGSAQEQSRHGSRHPRSHHEDRAGHGHSADSSRQSGTPHAETSSGGQAAS 1020
Query: 1021 SHEQARSSPGERHGSRHQQSADSSRHSGIPRRQASSAVRDSGHWGSSGSQASDSEGHSEE 1080
SHEQARSSPGERHGSRHQQSADSSRHSGIPRRQASSAVRDSGHWGSSGSQASDSEGHSEE
Sbjct: 1021 SHEQARSSPGERHGSRHQQSADSSRHSGIPRRQASSAVRDSGHWGSSGSQASDSEGHSEE 1080
Query: 1081 SDTQSVSGHGQDGPHQQSHQESARDWSGGRSGRSGSFIYQVSTHEQSESAHGRTRTSTGR 1140
SDTQSVSGHGQDGPHQQSHQESARDWSGGRSGRSGSFIYQVSTHEQSESAHGRTRTSTGR
Sbjct: 1081 SDTQSVSGHGQDGPHQQSHQESARDWSGGRSGRSGSFIYQVSTHEQSESAHGRTRTSTGR 1140
Query: 1141 RQGSHHEQARDSSRHSASQEGQDTIRAHPGSRRGGRQGSHHEQSVDRSGHSGSHHSHTTS 1200
RQGSHHEQARDSSRHSASQEGQDTIRAHPGSRRGGRQGSHHEQSVDRSGHSGSHHSHTTS
Sbjct: 1141 RQGSHHEQARDSSRHSASQEGQDTIRAHPGSRRGGRQGSHHEQSVDRSGHSGSHHSHTTS 1200
Query: 1201 QGRSDASHGQSGSRSASRQTRKDKQSGDGSRHSGSRHHEAASWADSSRHSQVGQEQSSGS 1260
QGRSDASHGQSGSRSASRQTRKDKQSGDGSRHSGSRHHEAASWADSSRHSQVGQEQSSGS
Sbjct: 1201 QGRSDASHGQSGSRSASRQTRKDKQSGDGSRHSGSRHHEAASWADSSRHSQVGQEQSSGS 1260
Query: 1261 RTSRHQGSSVSQDSDSERHSDDSERLSGSASRNHHGSSREQSRDGSRHPGFHQEDRASHG 1320
RTSRHQGSSVSQDSDSERHSDDSERLSGSASRNHHGSSREQSRDGSRHPGFHQEDRASHG
Sbjct: 1261 RTSRHQGSSVSQDSDSERHSDDSERLSGSASRNHHGSSREQSRDGSRHPGFHQEDRASHG 1320
Query: 1321 HSADSSRQSGTHHTESSSHGQAVSSHEQARSSPGERHGSRHQQSADSSRHSGIGHRQASS 1380
HSADSSRQSGTHHTESSSHGQAVSSHEQARSSPGERHGSRHQQSADSSRHSGIGHRQASS
Sbjct: 1321 HSADSSRQSGTHHTESSSHGQAVSSHEQARSSPGERHGSRHQQSADSSRHSGIGHRQASS 1380
Query: 1381 AVRDSGHRGSSGSQVTNSEGHSEDSDTQSVSAHGQAGPHQQSHKESARGQSGESSGRSRS 1440
AVRDSGHRGSSGSQVTNSEGHSEDSDTQSVSAHGQAGPHQQSHKESARGQSGESSGRSRS
Sbjct: 1381 AVRDSGHRGSSGSQVTNSEGHSEDSDTQSVSAHGQAGPHQQSHKESARGQSGESSGRSRS 1440
Query: 1441 FLYQVSSHEQSESTHGQTAPSTGGRQGSRHEQARNSSRHSASQDGQDTIRGHPGSSRGGR 1500
FLYQVSSHEQSESTHGQTAPSTGGRQGSRHEQARNSSRHSASQDGQDTIRGHPGSSRGGR
Sbjct: 1441 FLYQVSSHEQSESTHGQTAPSTGGRQGSRHEQARNSSRHSASQDGQDTIRGHPGSSRGGR 1500
Query: 1501 QGSYHEQSVDRSGHSGYHHSHTTPQGRSDASHGQSGPRSASRQTRNEEQSGDGSRHSGSR 1560
QGSYHEQSVDRSGHSGYHHSHTTPQGRSDASHGQSGPRSASRQTRNEEQSGDGSRHSGSR
Sbjct: 1501 QGSYHEQSVDRSGHSGYHHSHTTPQGRSDASHGQSGPRSASRQTRNEEQSGDGSRHSGSR 1560
Query: 1561 HHEPSTRAGSSRHSQVGQGESAGSKTSRRQGSSVSQDRDSEGHSEDSERRSESASRNHYG 1620
HHEPSTRAGSSRHSQVGQGESAGSKTSRRQGSSVSQDRDSEGHSEDSERRSESASRNHYG
Sbjct: 1561 HHEPSTRAGSSRHSQVGQGESAGSKTSRRQGSSVSQDRDSEGHSEDSERRSESASRNHYG 1620
Query: 1621 SAREQSRHGSRNPRSHQEDRASHGHSAESSRQSGTRHAETSSGGQAASSQEQARSSPGER 1680
SAREQSRHGSRNPRSHQEDRASHGHSAESSRQSGTRHAETSSGGQAASSQEQARSSPGER
Sbjct: 1621 SAREQSRHGSRNPRSHQEDRASHGHSAESSRQSGTRHAETSSGGQAASSQEQARSSPGER 1680
Query: 1681 HGSRHQQSADSSTDSGTGRRQDSSVVGDSGNRGSSGSQASDSEGHSEESDTQSVSAHGQA 1740
HGSRHQQSADSSTDSGTGRRQDSSVVGDSGNRGSSGSQASDSEGHSEESDTQSVSAHGQA
Sbjct: 1681 HGSRHQQSADSSTDSGTGRRQDSSVVGDSGNRGSSGSQASDSEGHSEESDTQSVSAHGQA 1740
Query: 1741 GPHQQSHQESTRGQSGERSGRSGSFLYQVSTHEQSESAHGRTGPSTGGRQRSRHEQARDS 1800
GPHQQSHQESTRGQSGERSGRSGSFLYQVSTHEQSESAHGRTGPSTGGRQRSRHEQARDS
Sbjct: 1741 GPHQQSHQESTRGQSGERSGRSGSFLYQVSTHEQSESAHGRTGPSTGGRQRSRHEQARDS 1800
Query: 1801 SRHSASQEGQDTIRGHPGSSRGGRQGSHYEQSVDSSGHSGSHHSHTTSQERSDVSRGQSG 1860
SRHSASQEGQDTIRGHPGSSRGGRQGSHYEQSVDSSGHSGSHHSHTTSQERSDVSRGQSG
Sbjct: 1801 SRHSASQEGQDTIRGHPGSSRGGRQGSHYEQSVDSSGHSGSHHSHTTSQERSDVSRGQSG 1860
Query: 1861 SRSVSRQTRNEKQSGDGSRHSGSRHHEASSRADSSRHSQVGQGQSSGPRTSRNQGSSVSQ 1920
SRSVSRQTRNEKQSGDGSRHSGSRHHEASSRADSSRHSQVGQGQSSGPRTSRNQGSSVSQ
Sbjct: 1861 SRSVSRQTRNEKQSGDGSRHSGSRHHEASSRADSSRHSQVGQGQSSGPRTSRNQGSSVSQ 1920
Query: 1921 DSDSQGHSEDSERWSGSASRNHLGSAWEQSRDGSRHPGSHHEDRAGHGHSADSSRQSGTR 1980
DSDSQGHSEDSERWSGSASRNHLGSAWEQSRDGSRHPGSHHEDRAGHGHSADSSRQSGTR
Sbjct: 1921 DSDSQGHSEDSERWSGSASRNHLGSAWEQSRDGSRHPGSHHEDRAGHGHSADSSRQSGTR 1980
Query: 1981 HTESSSRGQAASSHEQARSSAGERHGSHHQLQSADSSRHSGIGHGQASSAVRDSGHRGYS 2040
HTESSSRGQAASSHEQARSSAGERHGSHHQLQSADSSRHSGIGHGQASSAVRDSGHRGYS
Sbjct: 1981 HTESSSRGQAASSHEQARSSAGERHGSHHQLQSADSSRHSGIGHGQASSAVRDSGHRGYS 2040
Query: 2041 GSQASDSEGHSEDSDTQSVSAQGKAGPHQQSHKESARGQSGESSGRSGSFLYQVSTHEQS 2100
GSQASDSEGHSEDSDTQSVSAQGKAGPHQQSHKESARGQSGESSGRSGSFLYQVSTHEQS
Sbjct: 2041 GSQASDSEGHSEDSDTQSVSAQGKAGPHQQSHKESARGQSGESSGRSGSFLYQVSTHEQS 2100
Query: 2101 ESTHGQSAPSTGGRQGSHYDQAQDSSRHSASQEGQDTIRGHPGPSRGGRQGSHQEQSVDR 2160
ESTHGQSAPSTGGRQGSHYDQAQDSSRHSASQEGQDTIRGHPGPSRGGRQGSHQEQSVDR
Sbjct: 2101 ESTHGQSAPSTGGRQGSHYDQAQDSSRHSASQEGQDTIRGHPGPSRGGRQGSHQEQSVDR 2160
Query: 2161 SGHSGSHHSHTTSQGRSDASRGQSGSRSASRKTYDKEQSGDGSRHSGSHHHEASSWADSS 2220
SGHSGSHHSHTTSQGRSDASRGQSGSRSASRKTYDKEQSGDGSRHSGSHHHEASSWADSS
Sbjct: 2161 SGHSGSHHSHTTSQGRSDASRGQSGSRSASRKTYDKEQSGDGSRHSGSHHHEASSWADSS 2220
Query: 2221 RHSLVGQGQSSGPRTSRPRGSSVSQDSDSEGHSEDSERRSGSASRNHHGSAQEQSRDGSR 2280
RHSLVGQGQSSGPRTSRPRGSSVSQDSDSEGHSEDSERRSGSASRNHHGSAQEQSRDGSR
Sbjct: 2221 RHSLVGQGQSSGPRTSRPRGSSVSQDSDSEGHSEDSERRSGSASRNHHGSAQEQSRDGSR 2280
Query: 2281 HPRSHHEDRAGHGHSAESSRQSGTHHAENSSGGQAASSHEQARSSAGERHGSHHQQSADS 2340
HPRSHHEDRAGHGHSAESSRQSGTHHAENSSGGQAASSHEQARSSAGERHGSHHQQSADS
Sbjct: 2281 HPRSHHEDRAGHGHSAESSRQSGTHHAENSSGGQAASSHEQARSSAGERHGSHHQQSADS 2340
Query: 2341 SRHSGIGHGQASSAVRDSGHRGSSGSQASDSEGHSEDSDTQSVSAHGQAGPHQQSHQEST 2400
SRHSGIGHGQASSAVRDSGHRGSSGSQASDSEGHSEDSDTQSVSAHGQAGPHQQSHQEST
Sbjct: 2341 SRHSGIGHGQASSAVRDSGHRGSSGSQASDSEGHSEDSDTQSVSAHGQAGPHQQSHQEST 2400
Query: 2401 RGRSAGRSGRSGSFLYQVSTHEQSESAHGRTGTSTGGRQGSHHKQARDSSRHSTSQEGQD 2460
RGRSAGRSGRSGSFLYQVSTHEQSESAHGRTGTSTGGRQGSHHKQARDSSRHSTSQEGQD
Sbjct: 2401 RGRSAGRSGRSGSFLYQVSTHEQSESAHGRTGTSTGGRQGSHHKQARDSSRHSTSQEGQD 2460
Query: 2461 TIHGHPGSSSGGRQGSHYEQLVDRSGHSGSHHSHTTSQGRSDASHGHSGSRSASRQTRND 2520
TIHGHPGSSSGGRQGSHYEQLVDRSGHSGSHHSHTTSQGRSDASHGHSGSRSASRQTRND
Sbjct: 2461 TIHGHPGSSSGGRQGSHYEQLVDRSGHSGSHHSHTTSQGRSDASHGHSGSRSASRQTRND 2520
Query: 2521 EQSGDGSRHSGSRHHEASSRADSSGHSQVGQGQSEGPRTSRNWGSSFSQDSDSQGHSEDS 2580
EQSGDGSRHSGSRHHEASSRADSSGHSQVGQGQSEGPRTSRNWGSSFSQDSDSQGHSEDS
Sbjct: 2521 EQSGDGSRHSGSRHHEASSRADSSGHSQVGQGQSEGPRTSRNWGSSFSQDSDSQGHSEDS 2580
Query: 2581 ERWSGSASRNHHGSAQEQLRDGSRHPRSHQEDRAGHGHSADSSRQSGTRHTQTSSGGQAA 2640
ERWSGSASRNHHGSAQEQLRDGSRHPRSHQEDRAGHGHSADSSRQSGTRHTQTSSGGQAA
Sbjct: 2581 ERWSGSASRNHHGSAQEQLRDGSRHPRSHQEDRAGHGHSADSSRQSGTRHTQTSSGGQAA 2640
Query: 2641 SSHEQARSSAGERHGSHHQQSADSSRHSGIGHGQASSAVRDSGHRGYSGSQASDNEGHSE 2700
SSHEQARSSAGERHGSHHQQSADSSRHSGIGHGQASSAVRDSGHRGYSGSQASDNEGHSE
Sbjct: 2641 SSHEQARSSAGERHGSHHQQSADSSRHSGIGHGQASSAVRDSGHRGYSGSQASDNEGHSE 2700
Query: 2701 DSDTQSVSAHGQAGSHQQSHQESARGRSGETSGHSGSFLYQVSTHEQSESSHGWTGPSTR 2760
DSDTQSVSAHGQAGSHQQSHQESARGRSGETSGHSGSFLYQVSTHEQSESSHGWTGPSTR
Sbjct: 2701 DSDTQSVSAHGQAGSHQQSHQESARGRSGETSGHSGSFLYQVSTHEQSESSHGWTGPSTR 2760
Query: 2761 GRQGSRHEQAQDSSRHSASQDGQDTIRGHPGSSRGGRQGYHHEHSVDSSGHSGSHHSHTT 2820
GRQGSRHEQAQDSSRHSASQDGQDTIRGHPGSSRGGRQGYHHEHSVDSSGHSGSHHSHTT
Sbjct: 2761 GRQGSRHEQAQDSSRHSASQDGQDTIRGHPGSSRGGRQGYHHEHSVDSSGHSGSHHSHTT 2820
Query: 2821 SQGRSDASRGQSGSRSASRTTRNEEQSGDGSRHSGSRHHEASTHADISRHSQAVQGQSEG 2880
SQGRSDASRGQSGSRSASRTTRNEEQSGDGSRHSGSRHHEASTHADISRHSQAVQGQSEG
Sbjct: 2821 SQGRSDASRGQSGSRSASRTTRNEEQSGDGSRHSGSRHHEASTHADISRHSQAVQGQSEG 2880
Query: 2881 SRRSRRQGSSVSQDSDSEGHSEDSERWSGSASRNHHGSAQEQLRDGSRHPRSHQEDRAGH 2940
SRRSRRQGSSVSQDSDSEGHSEDSERWSGSASRNHHGSAQEQLRDGSRHPRSHQEDRAGH
Sbjct: 2881 SRRSRRQGSSVSQDSDSEGHSEDSERWSGSASRNHHGSAQEQLRDGSRHPRSHQEDRAGH 2940
Query: 2941 GHSADSSRQSGTRHTQTSSGGQAASSHEQARSSAGERHGSHHQQSADSSRHSGIGHGQAS 3000
GHSADSSRQSGTRHTQTSSGGQAASSHEQARSSAGERHGSHHQQSADSSRHSGIGHGQAS
Sbjct: 2941 GHSADSSRQSGTRHTQTSSGGQAASSHEQARSSAGERHGSHHQQSADSSRHSGIGHGQAS 3000
Query: 3001 SAVRDSGHRGYSGSQASDNEGHSEDSDTQSVSAHGQAGSHQQSHQESARGRSGETSGHSG 3060
SAVRDSGHRGYSGSQASDNEGHSEDSDTQSVSAHGQAGSHQQSHQESARGRSGETSGHSG
Sbjct: 3001 SAVRDSGHRGYSGSQASDNEGHSEDSDTQSVSAHGQAGSHQQSHQESARGRSGETSGHSG 3060
Query: 3061 SFLYQVSTHEQSESSHGWTGPSTRGRQGSRHEQAQDSSRHSASQYGQDTIRGHPGSSRGG 3120
SFLYQVSTHEQSESSHGWTGPSTRGRQGSRHEQAQDSSRHSASQYGQDTIRGHPGSSRGG
Sbjct: 3061 SFLYQVSTHEQSESSHGWTGPSTRGRQGSRHEQAQDSSRHSASQYGQDTIRGHPGSSRGG 3120
Query: 3121 RQGYHHEHSVDSSGHSGSHHSHTTSQGRSDASRGQSGSRSASRTTRNEEQSGDSSRHSVS 3180
RQGYHHEHSVDSSGHSGSHHSHTTSQGRSDASRGQSGSRSASRTTRNEEQSGDSSRHSVS
Sbjct: 3121 RQGYHHEHSVDSSGHSGSHHSHTTSQGRSDASRGQSGSRSASRTTRNEEQSGDSSRHSVS 3180
Query: 3181 RHHEASTHADISRHSQAVQGQSEGSRRSRRQGSSVSQDSDSEGHSEDSERWSGSASRNHR 3240
RHHEASTHADISRHSQAVQGQSEGSRRSRRQGSSVSQDSDSEGHSEDSERWSGSASRNHR
Sbjct: 3181 RHHEASTHADISRHSQAVQGQSEGSRRSRRQGSSVSQDSDSEGHSEDSERWSGSASRNHR 3240
Query: 3241 GSVQEQSRHGSRHPRSHHEDRAGHGHSADRSRQSGTRHAETSSGGQAASSHEQARSSPGE 3300
GSVQEQSRHGSRHPRSHHEDRAGHGHSADRSRQSGTRHAETSSGGQAASSHEQARSSPGE
Sbjct: 3241 GSVQEQSRHGSRHPRSHHEDRAGHGHSADRSRQSGTRHAETSSGGQAASSHEQARSSPGE 3300
Query: 3301 RHGSRHQQSADSSRHSGIPRGQASSAVRDSRHWGSSGSQASDSEGHSEESDTQSVSGHGQ 3360
RHGSRHQQSADSSRHSGIPRGQASSAVRDSRHWGSSGSQASDSEGHSEESDTQSVSGHGQ
Sbjct: 3301 RHGSRHQQSADSSRHSGIPRGQASSAVRDSRHWGSSGSQASDSEGHSEESDTQSVSGHGQ 3360
Query: 3361 AGPHQQSHQESARDRSGGRSGRSGSFLYQVSTHEQSESAHGRTRTSTGRRQGSHHEQARD 3420
AGPHQQSHQESARDRSGGRSGRSGSFLYQVSTHEQSESAHGRTRTSTGRRQGSHHEQARD
Sbjct: 3361 AGPHQQSHQESARDRSGGRSGRSGSFLYQVSTHEQSESAHGRTRTSTGRRQGSHHEQARD 3420
Query: 3421 SSRHSASQEGQDTIRGHPGSSRRGRQGSHYEQSVDRSGHSGSHHSHTTSQGRSDASRGQS 3480
SSRHSASQEGQDTIRGHPGSSRRGRQGSHYEQSVDRSGHSGSHHSHTTSQGRSDASRGQS
Sbjct: 3421 SSRHSASQEGQDTIRGHPGSSRRGRQGSHYEQSVDRSGHSGSHHSHTTSQGRSDASRGQS 3480
Query: 3481 GSRSASRQTRNDEQSGDGSRHSWSHHHEASTQADSSRHSQSGQGQSAGPRTSRNQGSSVS 3540
GSRSASRQTRNDEQSGDGSRHSWSHHHEASTQADSSRHSQSGQGQSAGPRTSRNQGSSVS
Sbjct: 3481 GSRSASRQTRNDEQSGDGSRHSWSHHHEASTQADSSRHSQSGQGQSAGPRTSRNQGSSVS 3540
Query: 3541 QDSDSQGHSEDSERWSGSASRNHRGSAQEQSRDGSRHPTSHHEDRAGHGHSAESSRQSGT 3600
QDSDSQGHSEDSERWSGSASRNHRGSAQEQSRDGSRHPTSHHEDRAGHGHSAESSRQSGT
Sbjct: 3541 QDSDSQGHSEDSERWSGSASRNHRGSAQEQSRDGSRHPTSHHEDRAGHGHSAESSRQSGT 3600
Query: 3601 HHAENSSGGQAASSHEQARSSAGERHGSHHQQSADSSRHSGIGHGQASSAVRDSGHRGSS 3660
HHAENSSGGQAASSHEQARSSAGERHGSHHQQSADSSRHSGIGHGQASSAVRDSGHRGSS
Sbjct: 3601 HHAENSSGGQAASSHEQARSSAGERHGSHHQQSADSSRHSGIGHGQASSAVRDSGHRGSS 3660
Query: 3661 GSQASDSEGHSEDSDTQSVSAHGQAGPHQQSHQESTRGRSAGRSGRSGSFLYQVSTHEQS 3720
GSQASDSEGHSEDSDTQSVSAHGQAGPHQQSHQESTRGRSAGRSGRSGSFLYQVSTHEQS
Sbjct: 3661 GSQASDSEGHSEDSDTQSVSAHGQAGPHQQSHQESTRGRSAGRSGRSGSFLYQVSTHEQS 3720
Query: 3721 ESAHGRAGPSTGGRQGSRHEQARDSSRHSASQEGQDTIRGHPGSRRGGRQGSYHEQSVDR 3780
ESAHGRAGPSTGGRQGSRHEQARDSSRHSASQEGQDTIRGHPGSRRGGRQGSYHEQSVDR
Sbjct: 3721 ESAHGRAGPSTGGRQGSRHEQARDSSRHSASQEGQDTIRGHPGSRRGGRQGSYHEQSVDR 3780
Query: 3781 SGHSGSHHSHTTSQGRSDASHGQSGSRSASRETRNEEQSGDGSRHSGSRHHEASTQADSS 3840
SGHSGSHHSHTTSQGRSDASHGQSGSRSASRETRNEEQSGDGSRHSGSRHHEASTQADSS
Sbjct: 3781 SGHSGSHHSHTTSQGRSDASHGQSGSRSASRETRNEEQSGDGSRHSGSRHHEASTQADSS 3840
Query: 3841 RHSQSGQGESAGSRRSRRQGSSVSQDSDSEAYPEDSERRSESASRNHHGSSREQSRDGSR 3900
RHSQSGQGESAGSRRSRRQGSSVSQDSDSEAYPEDSERRSESASRNHHGSSREQSRDGSR
Sbjct: 3841 RHSQSGQGESAGSRRSRRQGSSVSQDSDSEAYPEDSERRSESASRNHHGSSREQSRDGSR 3900
Query: 3901 HPGSSHRDTASHVQSSPVQSDSSTAKEHGHFSSLSQDSAYHSGIQSRGSPHSSSSYHYQS 3960
HPGSSHRDTASHVQSSPVQSDSSTAKEHGHFSSLSQDSAYHSGIQSRGSPHSSSSYHYQS
Sbjct: 3901 HPGSSHRDTASHVQSSPVQSDSSTAKEHGHFSSLSQDSAYHSGIQSRGSPHSSSSYHYQS 3960
Query: 3961 EGTERQKGQSGLVWRHGSYGSADYDYGESGFRHSQHGSVSYNSNPVVFKERSDICKASAF 4020
EGTERQKGQSGLVWRHGSYGSADYDYGESGFRHSQHGSVSYNSNPVVFKERSDICKASAF
Sbjct: 3961 EGTERQKGQSGLVWRHGSYGSADYDYGESGFRHSQHGSVSYNSNPVVFKERSDICKASAF 4020
Query: 4021 GKDHPRYYATYINKDPGLCGHSSDISKQLGFSQSQRYYYYE 4061
GKDHPRYYATYINKDPGLCGHSSDISKQLGFSQSQRYYYYE
Sbjct: 4021 GKDHPRYYATYINKDPGLCGHSSDISKQLGFSQSQRYYYYE 4061
>gi|57864582 hornerin [Homo sapiens]
Length = 2850
Score = 882 bits (2278), Expect = 0.0
Identities = 956/3018 (31%), Positives = 1244/3018 (41%), Gaps = 385/3018 (12%)
Query: 1 MSTLLENIFAIINLFKQYSKKDKNTDTLSKKELKELLEKEFRQILKNPDDPDMVDVFMDH 60
M LL+ + +I++F QY+ + DTL+K ELKELLE EF QILKNP+DPD VD+ +
Sbjct: 1 MPKLLQGVITVIDVFYQYATQHGEYDTLNKAELKELLENEFHQILKNPNDPDTVDIILQS 60
Query: 61 LDIDHNKKIDFTEFLLMVFKLAQAYYESTRKENLPISGHKHR--KHSHHDKHEDNKQEEN 118
LD DHNKK+DFTE+LLM+FKL QA + K+ +SG K R H H ++ E+ ++EEN
Sbjct: 61 LDRDHNKKVDFTEYLLMIFKLVQARNKIIGKDYCQVSGSKLRDDTHQHQEEQEETEKEEN 120
Query: 119 KE-----NRKRPSSLERRNNRKGNKGRSKSPRETGGKR----------HESSSEKKERKG 163
K + S+ E + + +G K E+ +R H S S + G
Sbjct: 121 KRQESSFSHSSWSAGENDSYSRNVRGSLKPGTESISRRLSFQRDFSGQHNSYSGQSSSYG 180
Query: 164 YSPTHREEEYGKNHHNSSKKEKNKTENTRLGDNRKRLSERLEEKEDNEEGVYDYENTGRM 223
+ + G+ S + G + ++ G ++++
Sbjct: 181 EQNSDSHQSSGRGQCGSGSGQSPNYGQHGSGSGQSSSNDTHGSGSGQSSGFSQHKSSSGQ 240
Query: 224 TQKWIQSGHIATYYTIQDEAYDTTDSLLEENKIYERSRSSDGKSSSQVNRSRHENTSQVP 283
+ + Q G + + Y S ++ ER RSS G SSS +H + S+
Sbjct: 241 SSGYSQHGSGSGH----SSGYGQHGSRSGQSSRGERHRSSSGSSSSY---GQHGSGSRQS 293
Query: 284 LQESRTRKRRGSRVSQDR----DSEGHSEDSERH-SGSA---SRNH-------------H 322
L R+ GSR S GHS +H SGS+ SR H H
Sbjct: 294 L--GHGRQGSGSRQSPSHVRHGSGSGHSSSHGQHGSGSSYSYSRGHYESGSGQTSGFGQH 351
Query: 323 GSAWEQSRDGSRH--PRSHDEDRASHGHS---ADSSRQSGTRHAETSSRGQ--TASSHEQ 375
S QS S+H H + HG + A SS Q G+ ++SS GQ +AS H
Sbjct: 352 ESGSGQSSGYSKHGSGSGHSSSQGQHGSTSGQASSSGQHGSSSRQSSSYGQHESASRHSS 411
Query: 376 AR--------SSPGE-RHGSGHQQSADSSRHSATGRGQASSA---VSDRGHRGSSGSQAS 423
R SPG + GSG QS S +H TG G++SS+ VS G+ G S
Sbjct: 412 GRGQHSSGSGQSPGHGQRGSGSGQSPSSGQH-GTGFGRSSSSGPYVSGSGYSSGFGHHES 470
Query: 424 DSEGHS----ENSDTQSVSGHGKAGLRQQSHQESTRGRSGERSGRSGSSLYQVSTHEQPD 479
SE S S + SGHG+ G R +S+RG S S SS Q + +
Sbjct: 471 SSEHSSGYTQHGSGSGHSSGHGQHGSRS---GQSSRGERQGSSAGSSSSYGQHGSGSRQS 527
Query: 480 SAHGRTGTSTG----GRQGSHHEQARDSSRHS--ASQEGQDTIRGHPGSSRGGRQGSHHE 533
H R G+ +G +G H +R SS + G+ + RG S G G H+
Sbjct: 528 LGHSRHGSGSGQSPSPSRGRHESGSRQSSSYGPHGYGSGRSSSRGPYESGSGHSSGLGHQ 587
Query: 534 QSVNRSGHSGSHHSHTTSQGRSDASHGQSGSRSASRQTRNEEQSGDGTRHSGSRHHEASS 593
+S RSG S + H +S G S ++HGQ GS S + + + G S +H SS
Sbjct: 588 ES--RSGQSSGYGQHGSSSGHS-STHGQHGSTSGQSSSCGQHGATSGQSSSHGQHGSGSS 644
Query: 594 QADSSRHSQVGQGQSSGPRTSRNQGSSVSQDSDSQGHSEDSERWSGSASRNHHGSAQEQS 653
Q SSR+ Q QG SG SR + S S S G W S+S HGS QS
Sbjct: 645 Q--SSRYGQ--QGSGSGQSPSRGRHGSDFGHSSSYGQHGSGSGW--SSSNGPHGSVSGQS 698
Query: 654 -----RDGSRHPRSHHEDRAGHGHSADSSRKSGTRHTQNSSSGQAASSHEQARSSAGERH 708
+ GS + + +G HS+ RK G+R Q+S S Q SS SS+ +H
Sbjct: 699 SGFGHKSGSGQSSGYSQHGSGSSHSS-GYRKHGSRSGQSSRSEQHGSS--SGLSSSYGQH 755
Query: 709 GSRHQLQSADSSRHSGTGHGQASSAVR---DSGHRGS-----SGSQATDSEGHSEDSDTQ 760
GS S + SG+GH + S VR SGH S SG+ + S GH E Q
Sbjct: 756 GSGSHQSSGHGRQGSGSGH--SPSRVRHGSSSGHSSSHGQHGSGTSCSSSCGHYESGSGQ 813
Query: 761 SVSGHGQ--AGHHQQSHQESARDRSGERSRRSGSFLYQVSTHKQSESSHGWTGPSTGVRQ 818
+ SG GQ +G Q Q + R GS Q S+ Q +SS G +
Sbjct: 814 A-SGFGQHESGSGQGYSQHGSASGHFSSQGRHGSTSGQSSSSGQHDSSSGQSSSYGQHES 872
Query: 819 GSHHEQARDNSRHSASQDGQDTIRGHPGSSRRGRQGSHHEQSVDRSGHSGSHHSHTTSQG 878
SHH R RH S GQ PG +RG GS S R G SGS S +S G
Sbjct: 873 ASHHASGR--GRH-GSGSGQS-----PGHGQRG-SGSGQSPSYGRHG-SGSGRS--SSSG 920
Query: 879 RSDASRGQS---GSRSASRTTRNEEQSRDGSRHSGSRHHEASSHADISRHSQAGQGQSEG 935
R + GQS G +S+S + Q GS HS S S SR Q G S G
Sbjct: 921 RHGSGSGQSSGFGHKSSSGQSSGYTQHGSGSGHSSSYEQHGSRSGQSSRSEQ--HGSSSG 978
Query: 936 SRTSRRQGSSVSQDSDSEGHSEDSERWSGSASRNHRGSAQEQS------RHGSRHPRSHH 989
S +S Q S S+ S G S S SR GS QS R GS S
Sbjct: 979 SSSSYGQHGSGSRQSLGHGQHGSGSGQSPSPSRGRHGSGSGQSSSYGPYRSGSGWSSSRG 1038
Query: 990 EDRAGHGHSADSSRQSGTPHAETSSGGQAASSHEQARSSPGERHGSRHQQSADSSRHSGI 1049
+G GHS SG H E+ SG +S + Q SS G H S H Q +S S
Sbjct: 1039 PYESGSGHS------SGLGHRESRSG--QSSGYGQHGSSSG--HSSTHGQHGSTSGQSSS 1088
Query: 1050 PRRQASSAVRDSGHWGSSGSQASDSEGHSEESDTQSVS-GHGQDGPHQQSHQESARDWSG 1108
+ +S+ + S H G GS +S S G+ + S GHGQ G + R SG
Sbjct: 1089 CGQHGASSGQSSSH-GQHGSGSSQSSGYGRQGSGSGQSPGHGQRGSGSRQSPSYGRHGSG 1147
Query: 1109 -GR---SGRSGSFIYQVSTHEQSESAHGRTRTSTGRRQGSHHEQ--ARDSSRHSASQEGQ 1162
GR SG+ GS + + S ES+ G++ + + GS H + SR S G+
Sbjct: 1148 SGRSSSSGQHGSGLGESSGFGHHESSSGQSSSYSQHGSGSGHSSGYGQHGSRSGQSSRGE 1207
Query: 1163 -----DTIRAHPGSR-RGGRQGSHHEQSVDRSGHSGSHHSHTTSQGRSDASHGQSGS--- 1213
+H G G RQ S H + SGHS S H + G S +SHGQ GS
Sbjct: 1208 RHGSSSGSSSHYGQHGSGSRQSSGHGRQGSGSGHSPSRGRHGSGLGHS-SSHGQHGSGSG 1266
Query: 1214 RSASR---QTRKDKQSGDGSRHSGSRHHEAAS---------------WADSSRHSQVGQE 1255
RS+SR ++R S G SGS H A S + S + S QE
Sbjct: 1267 RSSSRGPYESRSGHSSVFGQHESGSGHSSAYSQHGSGSGHFCSQGQHGSTSGQSSTFDQE 1326
Query: 1256 QSSGSRTSR--HQGSSVSQDSDSERHSDDSERLSGSASRNHHGSSREQSRDGSRHPGFHQ 1313
SS ++S H+GS SQ S RH S + S SR HGS S +H
Sbjct: 1327 GSSTGQSSSYGHRGSGSSQSSGYGRHGAGSGQ---SPSRGRHGSGSGHSSSYGQHGSGSG 1383
Query: 1314 EDRASHGHSADSSRQSGTHHTESS---SHGQAVSSHEQARSSPGERHGSRHQQSADSSRH 1370
+S H + S + SG H ESS S G SS E+HGSR QS+ RH
Sbjct: 1384 WSSSSGRHGSGSGQSSGFGHHESSSWQSSGCTQHGSGSGHSSSYEQHGSRSGQSSRGERH 1443
Query: 1371 SGIGHRQASSAVRDSGHRGSSGSQVTNSEGHSEDSDTQSVSAHGQAGPHQQSHKESARGQ 1430
+S SG R S G HGQ G +RG+
Sbjct: 1444 GSSSGSSSSYGQHGSGSRQSLG--------------------HGQHGSGSGQSPSPSRGR 1483
Query: 1431 SGESSGRSRSFLYQVSSHEQSES----THGQTAPSTGGRQGSRHEQARNSSRHSASQDGQ 1486
G SG+S S+ S S S G + S G + SR Q+ +H +S G
Sbjct: 1484 HGSGSGQSSSYSPYGSGSGWSSSRGPYESGSSHSSGLGHRESRSGQSSGYGQHGSS-SGH 1542
Query: 1487 DTIRGHPGSSRGGRQGSYHEQSVDRSGHSGYHHSHTTPQGRSDASHGQSGPRSASRQTRN 1546
+ G GS+ G Q S Q SG S H H + +S + +G+ G S S Q+
Sbjct: 1543 SSTHGQHGSTSG--QSSSCGQHGASSGQSSSHGQHGSGSSQS-SGYGRQG--SGSGQSPG 1597
Query: 1547 EEQSGDGSRHSGS--RHHEPSTRAGSSRHSQVGQGESAG---SKTSRRQGSSVSQDRDSE 1601
Q G GSR S S RH S R+ SS G GES+G ++S Q SS SQ
Sbjct: 1598 HGQRGSGSRQSPSYGRHGSGSGRSSSSGQHGSGLGESSGFGHHESSSGQSSSYSQHGSGS 1657
Query: 1602 GHS-----EDSERRSESASRNHYGSAREQSRHGSRNPRSHQEDRASHGHSAESSRQSGTR 1656
GHS S S H S+R SR+G S Q + HG S QS +R
Sbjct: 1658 GHSSGYGQHGSRSGQSSRGERHGSSSRSSSRYGQHGSGSRQS--SGHGRQGSGSGQSPSR 1715
Query: 1657 HAETSSGGQAAS-SQEQARSSPGERHGSRHQQSADSST----DSGTGR----RQDSSVVG 1707
S G ++S Q + S G +S SS +SG+G Q S G
Sbjct: 1716 GRHGSGLGHSSSHGQHGSGSGRSSSRGPYESRSGHSSVFGQHESGSGHSSAYSQHGSGSG 1775
Query: 1708 DSGNRGSSGSQASDSEGHSEE-SDTQSVSAHGQAGPHQQSHQESTRGQSGERSGRSGSFL 1766
++G GS + S +E S T S+HGQ G S Q S+ GQ G SG+S S
Sbjct: 1776 HFCSQGQHGSTSGQSSTFDQEGSSTGQSSSHGQHG--SGSSQSSSYGQQGSGSGQSPS-- 1831
Query: 1767 YQVSTHEQSESAHGRTGPSTGGRQRSRHEQARDSSRHSASQEGQDTIRGHPGSSRGGRQG 1826
+ G S+ G+ S + S RH S GQ + GH SS Q
Sbjct: 1832 -------RGRHGSGSGHSSSYGQHGSGSGWSSSSGRH-GSGSGQSSGFGHHESS--SWQS 1881
Query: 1827 SHYEQSVDSSGHSGSHHSHTTSQERSDVSRGQSGSRSVSRQTRNEKQSGDGSRHSGSRHH 1886
S Y Q SGHS S+ H GSR S Q+ +Q G S S S
Sbjct: 1882 SGYTQHGSGSGHSSSYEQH--------------GSR--SGQSSRGEQHGSSSGSSSSYGQ 1925
Query: 1887 EASSRADSSRHSQVGQGQSSGPRTSRNQGSSVSQDSDSQGHSEDSERWSGSASRNHLGSA 1946
S S H Q G G P SR + S S S S G WS S GS
Sbjct: 1926 HGSGSRQSLGHGQHGSGSGQSPSPSRGRHGSGSGQSSSYGPYGSGSGWSSSRGPYESGSG 1985
Query: 1947 WEQSRDGSRHPGSHHEDRAGHGHSADSSRQSGTRHTESSSRGQAASSHEQARSSA-GERH 2005
G H S +G+G SS S T S+ GQ++S + SS H
Sbjct: 1986 ---HSSGLGHRESRSGQSSGYGQHGSSSGHSSTHGQHGSASGQSSSCGQHGASSGQSSSH 2042
Query: 2006 GSHHQLQSADSSRHSGIG-HGQASSAVRDSGHRGYSGSQASDSEG-HSEDSDTQSVSAQG 2063
G H + SS+ SG G G S G RG SGS+ S S G H S S S Q
Sbjct: 2043 GQH----GSGSSQSSGYGRQGSGSGQSPGHGQRG-SGSRQSPSYGRHGSGSGRSSSSGQH 2097
Query: 2064 KAGPHQQS---HKESARGQS------GESSGRSGSFLYQVSTHEQSE--STHGQSAPSTG 2112
G + S H ES+ GQS G SG S + S QS HG S+ S+
Sbjct: 2098 GPGLGESSGFGHHESSSGQSSSYSQHGSGSGHSSGYGQHGSRSGQSSRGERHGSSSGSS- 2156
Query: 2113 GRQGSHYDQAQDSSRHSASQEGQDTIRGHPGPSRGGRQGSHQEQSVDRSGHSGSHHSHTT 2172
S Y Q SR S+ Q + GH PSR GR GS SGHS SH H +
Sbjct: 2157 ----SRYGQHGSGSRQSSGHGRQGSGSGH-SPSR-GRHGS-------GSGHSSSHGQHGS 2203
Query: 2173 SQGRSDASRGQSGSRSASRKTYDKEQSGDGSRHSGSHHHEASSWADSSRHSLVGQGQSSG 2232
GRS +SRG SRS + + +SG G + S H S S GQSS
Sbjct: 2204 GSGRS-SSRGPYESRSGHSSVFGQHESGSGHSSAYSQHGSGSGHFCSQGQHGSTSGQSS- 2261
Query: 2233 PRTSRPRGSSVSQDSDSEGHSEDSERRSGSASRNHHGSAQEQSR----DGSRHPRSHHED 2288
T GSS Q S S G +S S + GS Q SR GS H S+ +
Sbjct: 2262 --TFDQEGSSTGQ-SSSHGQHGSGSSQSSSYGQQGSGSGQSPSRGRHGSGSGHSSSYGQH 2318
Query: 2289 RAGHGHSAESSRQSGTHHAENSSGGQAASSHEQARSSAGERHGSHHQQSADSSRHSGIGH 2348
+G G S+ S R G+ ++S G SS Q SS +HGS S+ +H G
Sbjct: 2319 GSGSGWSSSSGRH-GSGSGQSSGFGHHESSSWQ--SSGYTQHGSGSGHSSSYEQH-GSRS 2374
Query: 2349 GQASSAVRDSGHRGSSGSQASDSEGHSEDSDTQSVSAHGQAGPHQQSHQESTRGRSAGRS 2408
GQ+S G R S S +S S G QS+ HGQ G +RGR S
Sbjct: 2375 GQSS-----RGERHGSSSGSSSSYGQHGSGSRQSL-GHGQHGSGSGQSPSPSRGRHGSGS 2428
Query: 2409 GRSGSFLYQVSTHEQSESAHGRTGTSTGGRQGSHHKQARDS-----SRHSTSQEGQDTIH 2463
G+S S+ S S S+ G + +G G H+++R +H +S G + H
Sbjct: 2429 GQSSSYSPYGSGSGWS-SSRGPYESGSGHSSGLGHRESRSGQSSGYGQHGSS-SGHSSTH 2486
Query: 2464 GHPGSSSGGRQGSHYEQLVDRSGHSGSHHSHTTSQGRSDASHGHSGSRSASRQTRNDEQS 2523
G GS+SG Q S Q SG S SH H + S S G+ S S Q+ Q
Sbjct: 2487 GQHGSTSG--QSSSCGQHGASSGQSSSHGQHGSG---SSQSSGYGRQGSGSGQSPGHGQR 2541
Query: 2524 GDGSRHSGS--RHHEASSRADSSGHSQVGQGQSEG---PRTSRNWGSSFSQDSDSQGHSE 2578
G GSR S S RH S R+ SSG G G+S G +S SS+SQ GH
Sbjct: 2542 GSGSRQSPSYGRHGSGSGRSSSSGQHGSGLGESSGFGHHESSSGQSSSYSQHGSGSGH-- 2599
Query: 2579 DSERWSGSASRNHHGSAQEQLRDGSRHPRSHQEDRAGHGHSADSSRQSGTRHTQTSSGGQ 2638
S+ HGS Q G RH S + +G SRQS Q S GQ
Sbjct: 2600 -------SSGYGQHGSRSGQSSRGERH-GSSSGSSSHYGQHGSGSRQSSGHGRQGSGSGQ 2651
Query: 2639 AASSHEQARSSAGERHGSHHQQSADSSRHSGIGHGQASSAVRDSGHRGYSG--SQASDNE 2696
+ S + R +G H S H Q G G G++SS G+S Q
Sbjct: 2652 SPS---RGRHGSGLGHSSSHGQ-------HGSGSGRSSSRGPYESRLGHSSVFGQHESGS 2701
Query: 2697 GHSEDSDTQSVSAHGQAGSHQQSHQESARGRSGETSGHSGSFLYQVSTHEQSESSHGWTG 2756
GHS + S HG H S +G+ G TSG S ST +Q SS G +
Sbjct: 2702 GHS-----SAYSQHGSGSGHFCS-----QGQHGSTSGQS-------STFDQEGSSTGQS- 2743
Query: 2757 PSTRGRQGSRHEQAQDSSRHSASQDGQDTIRGHPGSSRGGRQGYHHEHSVDSSGHSGSHH 2816
S+ G +GS Q+ RH A GQ G GS G Y S SG S +
Sbjct: 2744 -SSYGHRGSGSSQSSGYGRHGAG-SGQSLSHGRHGSGSGQSSSYGQHGS--GSGQSSGYS 2799
Query: 2817 SHTTSQGRSDASRGQSGS 2834
H + G+ S + GS
Sbjct: 2800 QHGSGSGQDGYSYCKGGS 2817
Score = 805 bits (2078), Expect = 0.0
Identities = 892/2980 (29%), Positives = 1177/2980 (39%), Gaps = 378/2980 (12%)
Query: 1247 SRHSQVGQE--QSSGS--RTSRHQGSSVSQDSDSERHSDDSERLSGSASRNHHGSSREQS 1302
+R+ +G++ Q SGS R HQ ++++ E + S S+ S ++
Sbjct: 84 ARNKIIGKDYCQVSGSKLRDDTHQHQEEQEETEKEENKRQESSFSHSSWSAGENDSYSRN 143
Query: 1303 RDGSRHPGFHQEDRASHGHSADSSRQSGTHHTESSSHGQAVSSHEQARSSPGERHGSRHQ 1362
GS PG R D S Q ++ +SSS+G+ S Q SS + GS
Sbjct: 144 VRGSLKPGTESISRRL-SFQRDFSGQHNSYSGQSSSYGEQNSDSHQ--SSGRGQCGSGSG 200
Query: 1363 QSADSSRHSGIGHRQASSAVRDSGHRGSSGSQVTNSEGHSEDSDTQSVSAHGQAGPHQQS 1422
QS + +H G G Q+SS + H SG S+ S + S HG H
Sbjct: 201 QSPNYGQH-GSGSGQSSS---NDTHGSGSGQSSGFSQHKSSSGQSSGYSQHGSGSGHSSG 256
Query: 1423 HKESARGQSGESSGRS-RSFLYQVSSHEQSESTHGQTAPSTGGRQGSRHEQARNSSRHSA 1481
+ GQ G SG+S R ++ SS S S++GQ +G RQ H + + SR S
Sbjct: 257 Y-----GQHGSRSGQSSRGERHRSSSG--SSSSYGQHG--SGSRQSLGHGRQGSGSRQSP 307
Query: 1482 SQDGQDTIRGHPGSSRGGRQGSYHEQSVDRSGHSGYHHSHTTPQGRSDASHGQSGPRSAS 1541
S + GH SS G+ GS S R GH T+ G+ ++ GQS S
Sbjct: 308 SHVRHGSGSGH--SSSHGQHGSGSSYSYSR-GHYESGSGQTSGFGQHESGSGQSSGYS-- 362
Query: 1542 RQTRNEEQSGDGSRHSGSRHHEPSTRAGSSRHSQVGQGESAGSKTSRRQGSSVSQDRDSE 1601
+ G GS HS S+ ST +S Q G + S+ S G S R S
Sbjct: 363 -------KHGSGSGHSSSQGQHGSTSGQASSSGQHG----SSSRQSSSYGQHESASRHSS 411
Query: 1602 GHSEDSERRSESASRNHYGSAREQSRHGSRNPRSHQEDRASHGHSAESSRQSGTRHAETS 1661
G + S +S GS QS ++ +S + + S SG H E+S
Sbjct: 412 GRGQHSSGSGQSPGHGQRGSGSGQSPSSGQHGTGFGRSSSSGPYVSGSGYSSGFGHHESS 471
Query: 1662 SGGQAASSQEQARSSPGERHGSRHQQSADSSTDSGTGRRQDSSVVGDSGNRGSSGSQASD 1721
S + +Q + G H S H Q S S G RQ SS G S + G GS +
Sbjct: 472 SEHSSGYTQHGS----GSGHSSGHGQHGSRSGQSSRGERQGSSA-GSSSSYGQHGSGSRQ 526
Query: 1722 SEGHSEESDTQSVSAHGQAGPHQQ-SHQESTRGQSGERSGRSGSFLYQVSTHEQSESAHG 1780
S GHS S G H+ S Q S+ G G SGRS S+ ES G
Sbjct: 527 SLGHSRHGSGSGQSPSPSRGRHESGSRQSSSYGPHGYGSGRS-------SSRGPYESGSG 579
Query: 1781 RTGPSTGGRQRSRHEQARDSSRHSASQEGQDTIRGHPGSSRGGRQGSHYEQSVDSSGHSG 1840
+ S G Q SR Q+ +H +S G + G GS+ G Q S Q +SG S
Sbjct: 580 HS--SGLGHQESRSGQSSGYGQHGSSS-GHSSTHGQHGSTSG--QSSSCGQHGATSGQSS 634
Query: 1841 SHHSHTTSQERSDVSRGQSGSRSVSRQTRNEKQSGDGSRHSGSRHHEASSRADSSR-HSQ 1899
SH H + +S GQ GS S +R S G S +H S + S+ H
Sbjct: 635 SHGQHGSGSSQSS-RYGQQGSGSGQSPSRGRHGSDFGHSSSYGQHGSGSGWSSSNGPHGS 693
Query: 1900 V-GQGQSSGPRTSRNQGSSVSQDSDSQGHSEDSERW---SGSASRN--HLGSAWEQSRDG 1953
V GQ G ++ Q S SQ HS + SG +SR+ H S+ S G
Sbjct: 694 VSGQSSGFGHKSGSGQSSGYSQHGSGSSHSSGYRKHGSRSGQSSRSEQHGSSSGLSSSYG 753
Query: 1954 SRHPGSHHEDRAGHGHSADSSRQSGTRHTESSSRGQAASSHEQARSSAGERHGSHHQLQS 2013
GSH +GHG S S +R SS G ++S + ++ H++ S
Sbjct: 754 QHGSGSHQS--SGHGRQGSGSGHSPSRVRHGSSSGHSSSHGQHGSGTSCSSSCGHYESGS 811
Query: 2014 ADSS----RHSGIG-----HGQASSAVRDSGHRGYSGSQASDSEGHSEDSDTQSVSAQGK 2064
+S SG G HG AS G G + Q+S S H S S Q +
Sbjct: 812 GQASGFGQHESGSGQGYSQHGSASGHFSSQGRHGSTSGQSSSSGQHDSSSGQSSSYGQHE 871
Query: 2065 AGPHQQSHKESARGQSGESSGRSGSFLYQVSTHEQSESTHGQSAPSTGGRQGSHYDQAQD 2124
+ SH S RG+ G SG+S H Q S GQS PS G R GS ++
Sbjct: 872 SA----SHHASGRGRHGSGSGQSPG-------HGQRGSGSGQS-PSYG-RHGSGSGRSSS 918
Query: 2125 SSRHSASQEGQDTIRGHPGPSRGGRQGSHQEQSVDRSGHSGSHHSHTTSQGRSDASRGQS 2184
S RH S GQ + GH S Q S Q SGHS S+ H + G+S S Q
Sbjct: 919 SGRHG-SGSGQSSGFGHKSSSG---QSSGYTQHGSGSGHSSSYEQHGSRSGQSSRSE-QH 973
Query: 2185 GSRSASRKTYDKEQSGDGSRHSGSHHHEASSWADSSRHSLVGQGQSSGPRTSRPRGSSVS 2244
GS S S +Y Q G GSR S H S G GQS P SR R S S
Sbjct: 974 GSSSGSSSSYG--QHGSGSRQSLGHGQHGS-----------GSGQSPSP--SRGRHGSGS 1018
Query: 2245 QDSDSEGHSEDSERRSGSASRNHHGSAQEQSRDGSRHPRSHHEDRAGHGHSAESSRQSGT 2304
S S G S S GS G H S +G+G SS S T
Sbjct: 1019 GQSSSYGPYRSGSGWSSSRGPYESGSGHSS---GLGHRESRSGQSSGYGQHGSSSGHSST 1075
Query: 2305 HHAENSSGGQAASSHEQARSSAGERHGSHHQQSADSSRHSGIG-----------HGQASS 2353
H S+ GQ++S + SS + SH Q + SS+ SG G HGQ S
Sbjct: 1076 HGQHGSTSGQSSSCGQHGASSG--QSSSHGQHGSGSSQSSGYGRQGSGSGQSPGHGQRGS 1133
Query: 2354 AVRDS---GHRGSSGSQASDSE------------GHSEDSDTQS--VSAHGQA------- 2389
R S G GS ++S S GH E S QS S HG
Sbjct: 1134 GSRQSPSYGRHGSGSGRSSSSGQHGSGLGESSGFGHHESSSGQSSSYSQHGSGSGHSSGY 1193
Query: 2390 GPHQQSHQESTRGRSAGRSGRSGSFLYQVSTHEQSESAHGRTGTSTGGRQGSHHKQARDS 2449
G H +S+RG G S S S Q + + S HGR G+ GS H +R
Sbjct: 1194 GQHGSRSGQSSRGERHGSSSGSSSHYGQHGSGSRQSSGHGRQGS------GSGHSPSR-- 1245
Query: 2450 SRHSTSQEGQDTIHGHPGSSSGGRQGSHYEQLVDRSGHSGSHHSHTTSQGRSDASHGH-S 2508
RH + G + HG GS SG + S RSGHS H + G S A H S
Sbjct: 1246 GRHGSGL-GHSSSHGQHGSGSG--RSSSRGPYESRSGHSSVFGQHESGSGHSSAYSQHGS 1302
Query: 2509 GSR---------SASRQTRNDEQSGDGSRHSGSRHHEASSRADSSGHSQVGQGQSEGPRT 2559
GS S S Q+ +Q G + S S H S + SSG+ + G G + P
Sbjct: 1303 GSGHFCSQGQHGSTSGQSSTFDQEGSSTGQSSSYGHRGSGSSQSSGYGRHGAGSGQSPSR 1362
Query: 2560 SRNWGSSFSQDSDSQGHSEDSERWSGSASRNHHGSAQEQLRDGSRHPRSHQEDRAGHGHS 2619
R+ S S S S G WS S+ R+ GS Q +G GH
Sbjct: 1363 GRH--GSGSGHSSSYGQHGSGSGWSSSSGRHGSGSGQS----------------SGFGHH 1404
Query: 2620 ADSSRQSGTRHTQTSSGGQAASSHEQ-----ARSSAGERHGSHHQQSADSSRHSG----- 2669
SS QS + TQ SG +SS+EQ +SS GERHGS S+ +H
Sbjct: 1405 ESSSWQS-SGCTQHGSGSGHSSSYEQHGSRSGQSSRGERHGSSSGSSSSYGQHGSGSRQS 1463
Query: 2670 IGHGQASSAVRDS-----GHRGYSGSQASDNEGHSEDSDTQSVSAHGQAGSHQQSHQESA 2724
+GHGQ S S G G Q+S + S S ++GS S
Sbjct: 1464 LGHGQHGSGSGQSPSPSRGRHGSGSGQSSSYSPYGSGSGWSSSRGPYESGSSHSSGLGHR 1523
Query: 2725 RGRSGETSGHS--GSFLYQVSTHEQSESSHGWTGPSTRGRQGSRHEQAQDSSRHSASQDG 2782
RSG++SG+ GS STH Q S+ G + S+ G+ G+ Q+ +H S
Sbjct: 1524 ESRSGQSSGYGQHGSSSGHSSTHGQHGSTSGQS--SSCGQHGASSGQSSSHGQHG-SGSS 1580
Query: 2783 QDTIRGHPGSSRGGRQGYHHEHSVDSSGHSGSHHSHTTSQGRSDASRGQSGSRSASRTTR 2842
Q + G GS G G+ S S S S+ H + GRS +S GQ GS +
Sbjct: 1581 QSSGYGRQGSGSGQSPGHGQRGS--GSRQSPSYGRHGSGSGRSSSS-GQHGSGLGESSGF 1637
Query: 2843 NEEQSGDGSRHSGSRHHEASTHADI-----SRHSQAVQGQSEGS--RRSRRQGSSVSQDS 2895
+S G S S+H S H+ SR Q+ +G+ GS R S R G S
Sbjct: 1638 GHHESSSGQSSSYSQHGSGSGHSSGYGQHGSRSGQSSRGERHGSSSRSSSRYGQHGSGSR 1697
Query: 2896 DSEGHSEDSERWSGSASRNHHGSAQEQLRDGSRHPRSHQEDRAGHGHSAD-SSRQSGTRH 2954
S GH S SR HGS G H SH + +G G S+ +S + H
Sbjct: 1698 QSSGHGRQGSGSGQSPSRGRHGS-------GLGHSSSHGQHGSGSGRSSSRGPYESRSGH 1750
Query: 2955 TQTSSGGQAASSHEQARSSAGERHGSHHQQSADSSRHSGIGHGQASSAVRDSGHRGYSGS 3014
+ ++ S H SSA +HGS +H G GQ+S+ ++ G S S
Sbjct: 1751 SSVFGQHESGSGH----SSAYSQHGSGSGHFCSQGQH-GSTSGQSSTFDQEGSSTGQSSS 1805
Query: 3015 QASDNEGHSEDSDTQSVSAHGQAGSHQQSHQESARGRSGETSGHSGSFLYQVSTHEQSES 3074
G S+ S++GQ GS S Q +RGR G SGHS S++ Q S
Sbjct: 1806 HGQHGSGSSQS------SSYGQQGS--GSGQSPSRGRHGSGSGHS-------SSYGQHGS 1850
Query: 3075 SHGWTGPSTRGRQGSRHEQAQDSSRHSASQYGQDTIRGHPGSSRGGRQGYHHEHSVDSSG 3134
GW+ S+ GR GS Q+ H +S + H GS G Y S SG
Sbjct: 1851 GSGWS--SSSGRHGSGSGQSSGFGHHESSSWQSSGYTQH-GSGSGHSSSYEQHGS--RSG 1905
Query: 3135 HSGSHHSHTTSQGRSDASRGQSGSRSASRTTRNEEQSGDSSRHSVSRHHEASTHADISRH 3194
S H +S G S +S GQ GS S + SG S SR S S +
Sbjct: 1906 QSSRGEQHGSSSG-SSSSYGQHGSGSRQSLGHGQHGSGSGQSPSPSRGRHGSGSGQSSSY 1964
Query: 3195 SQAVQGQ---------SEGSRRSRRQGSSVSQDSDSEGHSEDSERWSGSASRNHRGSVQE 3245
G GS S G S+ S G+ + S++ GS
Sbjct: 1965 GPYGSGSGWSSSRGPYESGSGHSSGLGHRESRSGQSSGYGQHGSSSGHSSTHGQHGSASG 2024
Query: 3246 QSRHGSRHPRSHHEDRAGHGHSADRSRQSGTRHAETSSGGQAASSHEQ----ARSSPG-E 3300
QS +H S + + H + S+ SG + SG + H Q +R SP
Sbjct: 2025 QSSSCGQHGASSGQSSSHGQHGSGSSQSSG--YGRQGSGSGQSPGHGQRGSGSRQSPSYG 2082
Query: 3301 RHGSRHQQSADSSRHS-GIPRGQASSAVRDSRHWGSSGSQASDSEGHSEESDTQSVSGHG 3359
RHGS +S+ S +H G+ S SS SQ GHS SG+G
Sbjct: 2083 RHGSGSGRSSSSGQHGPGLGESSGFGHHESSSGQSSSYSQHGSGSGHS--------SGYG 2134
Query: 3360 QAGPHQQSHQESARDRSGGRSGRSGSFLYQVSTHEQSESAHGRTRTSTGR--RQGSHHEQ 3417
Q G +S Q S +R G SG S + S QS S HGR + +G +G H
Sbjct: 2135 QHG--SRSGQSSRGERHGSSSGSSSRYGQHGSGSRQS-SGHGRQGSGSGHSPSRGRHGSG 2191
Query: 3418 ARDSSRHS--ASQEGQDTIRGHPGSSRRGRQGSHYEQSVDRSGHSGSHHSHTTSQGRSDA 3475
+ SS H S G+ + RG P SR G S + Q SGHS ++ H + G
Sbjct: 2192 SGHSSSHGQHGSGSGRSSSRG-PYESRSG-HSSVFGQHESGSGHSSAYSQHGSGSGHF-C 2248
Query: 3476 SRGQSGSRSASRQTRNDEQSGDGSRHSWSHHHEASTQADSSRHSQSGQGQSAGPRTSRNQ 3535
S+GQ GS S T + E S G S H S+Q+ S SG GQS SR +
Sbjct: 2249 SQGQHGSTSGQSSTFDQEGSSTGQSSSHGQHGSGSSQSSSYGQQGSGSGQS----PSRGR 2304
Query: 3536 GSSVSQDSDSQGHSEDSERWSGSASRNHRGSAQE-----------------QSRDGSRHP 3578
S S S S G WS S+ R+ GS Q Q GS H
Sbjct: 2305 HGSGSGHSSSYGQHGSGSGWSSSSGRHGSGSGQSSGFGHHESSSWQSSGYTQHGSGSGHS 2364
Query: 3579 TSH--HEDRAGHGHSAE---SSRQSGTHHAENSSGGQAASSHEQARSSAGE----RHGSH 3629
+S+ H R+G E SS S + + ++ SG + + H Q S +G+ G H
Sbjct: 2365 SSYEQHGSRSGQSSRGERHGSSSGSSSSYGQHGSGSRQSLGHGQHGSGSGQSPSPSRGRH 2424
Query: 3630 HQQSADSSRHSGIGHGQASSAVRDSGHRGSSGSQASDSEGHSEDSDTQS--VSAHGQAGP 3687
S SS +S G G S+ R SGS S GH E QS HG +
Sbjct: 2425 GSGSGQSSSYSPYGSGSGWSSSRGP---YESGSGHSSGLGHRESRSGQSSGYGQHGSSSG 2481
Query: 3688 HQQSHQE--STRGRSAGRSGRSGSFLYQVSTHEQ------SESAHGRAGPSTG-----GR 3734
H +H + ST G+S+ G+ G+ Q S+H Q S +GR G +G G+
Sbjct: 2482 HSSTHGQHGSTSGQSSS-CGQHGASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQSPGHGQ 2540
Query: 3735 QGSRHEQARDSSRHSASQEGQDTIRGHPGSRRGGRQGSYHEQSVDRSGHSGSHHSHTTSQ 3794
+GS Q+ RH S G+ + G GS G G H +S SG S S+ H +
Sbjct: 2541 RGSGSRQSPSYGRH-GSGSGRSSSSGQHGSGLGESSGFGHHES--SSGQSSSYSQHGSGS 2597
Query: 3795 GRSDASHGQSGSRSASRETRNEEQSGDGSRHSGSRHHEASTQADSSRHSQSGQGESAGSR 3854
G S + +GQ GSRS S GS +H S Q SS H + G G
Sbjct: 2598 GHS-SGYGQHGSRSGQSSRGERHGSSSGSSSHYGQHGSGSRQ--SSGHGRQGSGSGQSPS 2654
Query: 3855 RSRRQGSSVSQDSDSEAYPEDSERRSESA---SRNHHGSSREQSRDGSRHP------GSS 3905
R R GS + S + S R S SR H S Q GS H GS
Sbjct: 2655 RG-RHGSGLGHSSSHGQHGSGSGRSSSRGPYESRLGHSSVFGQHESGSGHSSAYSQHGSG 2713
Query: 3906 HRDTASHVQSSPVQSDSSTAKEHGHFSSLSQDSAYHSGIQSRGSPHSSSSYHYQSEGTER 3965
S Q SST + G SS Q S+Y RGS S QS G R
Sbjct: 2714 SGHFCSQGQHGSTSGQSSTFDQEG--SSTGQSSSY----GHRGSGSS------QSSGYGR 2761
Query: 3966 QKGQSGLVWRHGSYGSADYDYGESGFRHSQHGSVSYNSNPVVFKERSDICKASAFGKDHP 4025
SG HG +GS G+S + QHGS S S+ + + S G+D
Sbjct: 2762 HGAGSGQSLSHGRHGSGS---GQSS-SYGQHGSGSGQSSG--YSQH-----GSGSGQDGY 2810
Query: 4026 RYYATYINKDPGLCG----HSSDISKQLGFSQSQRYYYYE 4061
Y N D G G + + Q QR Y+Y+
Sbjct: 2811 SYCKGGSNHDGGSSGSYFLSFPSSTSPYEYVQEQRCYFYQ 2850
>gi|62122917 filaggrin family member 2 [Homo sapiens]
Length = 2391
Score = 756 bits (1952), Expect = 0.0
Identities = 760/2587 (29%), Positives = 1078/2587 (41%), Gaps = 425/2587 (16%)
Query: 1 MSTLLENIFAIINLFKQYSKKDKNTDTLSKKELKELLEKEFRQILKNPDDPDMVDVFMDH 60
M+ LL ++ +I++F +Y+K+D TLSK ELKELLEKE +LKNPDDPD VDV M
Sbjct: 1 MTDLLRSVVTVIDVFYKYTKQDGECGTLSKGELKELLEKELHPVLKNPDDPDTVDVIMHM 60
Query: 61 LDIDHNKKIDFTEFLLMVFKLAQAYYESTRKENLPISGHKHRKHSHHDKHEDNKQEENKE 120
LD DH++++DFTEFLLM+FKL A + KE SG K + H + E+++ EE++E
Sbjct: 61 LDRDHDRRLDFTEFLLMIFKLTMACNKVLSKEYCKASGSKKHRRGHRHQEEESETEEDEE 120
Query: 121 NRKRPSSLERRNNRKGNKGRSKSPRETGGK---RHESSSEKKERKG-YSPTHREEEYGKN 176
+ S R ++ + S + G RH S+S + R+G S + +E K
Sbjct: 121 DTPGHKSGYRHSSWSEGEEHGYSSGHSRGTVKCRHGSNSRRLGRQGNLSSSGNQEGSQKR 180
Query: 177 HHNSSKKEKNKTENTRLGDNRKRLSERLEEK--EDNEEGVYDYENTGRMTQKWIQSGHIA 234
+H SS R G + L ER+ + + E +YE +G + W + GH
Sbjct: 181 YHRSSCGHSWSGGKDRHGSSSVELRERINKSHISPSRESGEEYE-SGSGSNSWERKGHGG 239
Query: 235 TYYTIQDEAYD--TTDSLLEENKIYERSRSSDGKSSSQVNRSRHENTSQVPLQESRTRKR 292
++ ++ +T S + E K+ S S G S + + + N+S ++ +
Sbjct: 240 LSCGLETSGHESNSTQSRIREQKL-GSSCSGSGDSGRRSHACGYSNSSGCGRPQNASSSC 298
Query: 293 RGSRVSQDRDSEGHSEDSERHSGSASRNHHGSAWEQSRDGSRHPRSHDEDRASHGHSADS 352
+ R + + + S SG HG G P S+ + S+
Sbjct: 299 QSHRFGGQGNQFSYIQ-SGCQSGIKGGQGHGCVSGGQPSGCGQPESNPCSQ-SYSQRGYG 356
Query: 353 SRQSGTRHAETSSRGQTASSHEQARSSPGERHGSGHQQSADSSRHSATGRGQASSAVSDR 412
+R++G + + +T SS +SS ++GSG QS + +H G+ S++ S
Sbjct: 357 ARENG-QPQNCGGQWRTGSS----QSSCCGQYGSGGSQSCSNGQHEYGSCGRFSNSSSSN 411
Query: 413 -----GHRGSSGSQASDSEGH----SENSD-TQSVSGHGKAGLRQQSHQESTRG--RSGE 460
GS SQ++ E H S++S Q V G G+ + +S + G + G
Sbjct: 412 EFSKCDQYGSGSSQSTSFEQHGTGLSQSSGFEQHVCGSGQTCGQHESTSSQSLGYDQHGS 471
Query: 461 RSGRSGSSLYQVSTHEQPDSAHGRTGTSTG-----GRQGSHHEQARDSSRHSASQEGQDT 515
SG++ S Q + S G+ G+ +G G+ GS Q+ +H +
Sbjct: 472 SSGKT-SGFGQHGSGSGQSSGFGQCGSGSGQSSGFGQHGSVSGQSSGFGQHGSVSGQSSG 530
Query: 516 IRGHPGSSRGGRQGSHHEQSVNRSGHSGSHHSHTTSQGRSDASHGQS------GSRSASR 569
H SR G H S SG+ T+ G+ GQS GS S
Sbjct: 531 FGQHESRSRQSSYGQHGSGSSQSSGYGQYGSRETSGFGQHGLGSGQSTGFGQYGSGSGQS 590
Query: 570 QTRNEEQSGDGTRHSGSRHHEASSQADSSRHSQVGQGQSS-----GPRTSRNQGSSVSQD 624
+ SG G +H S Q+ +HS G QSS G R + G S
Sbjct: 591 SGFGQHGSGSGQSSGFGQHESRSGQSSYGQHSS-GSSQSSGYGQHGSRQTSGFGQHGSGS 649
Query: 625 SDSQGHSEDSERWSGSASRNHHGSAQEQSRDGSRHPRSHHEDRAGHG----HSADSSRKS 680
S S G + GS S G Q S G HE R+GH H SS+ S
Sbjct: 650 SQSTGFGQ-----YGSGSGQSSGFGQHVSGSGQSSGFGQHESRSGHSSYGQHGFGSSQSS 704
Query: 681 GTRHTQNSSSGQAA--SSHE--QARSSAGERHGSRHQLQSADSSRHSGTGHGQASSAVRD 736
G SSSGQ + HE +SS+ +HGS QS+ +H G+G GQ+S +
Sbjct: 705 GYGQ-HGSSSGQTSGFGQHELSSGQSSSFGQHGSGSG-QSSGFGQH-GSGSGQSSGFGQH 761
Query: 737 SGHRGSSGSQATDSEGHSEDSDTQSVSGHGQAGHHQQSHQESARDRSGERSRRSGSFLYQ 796
G S S G +QS SG+GQ G S Q S + G S +S F
Sbjct: 762 ESRSGQS------SYGQHSSGSSQS-SGYGQHG----SRQTSGFGQHGSGSSQSTGFGQY 810
Query: 797 VSTHKQSESSHGWTGPSTGVRQGSHHEQARDNSRHSASQDGQDTIRGHPGSSRRGRQGSH 856
S QS + G G +G G ++R + + S Q G GSS+ G H
Sbjct: 811 GSGSGQS-AGFGQHGSGSGQSSGFGQHESRSH-QSSYGQHGS-------GSSQSSGYGQH 861
Query: 857 HEQSVDRSGHSGSHHSHTTSQGRSDASRGQSGSRSASRTTRNEEQSRDGSRHSGSRHHEA 916
S SG H +S G+ + GQ GS S + + + G ++SG HE+
Sbjct: 862 GSSSGQTSGFG----QHRSSSGQY-SGFGQHGSGSGQSSGFGQHGTGSG-QYSGFGQHES 915
Query: 917 SSHADISRHSQAGQGQSEGSRTSRRQGSSVSQDSDSEGHSEDSERWS-----GSASRNHR 971
SH S + Q G G S+ S + GSS Q H S + S GS S
Sbjct: 916 RSHQ--SSYGQHGSGSSQSSGYG-QHGSSSGQTFGFGQHRSGSGQSSGFGQHGSGSGQSS 972
Query: 972 GSAQEQSRHGSRHPRSHHEDRAGHG----HSADSSRQSGTPHAETSSGGQAASSHEQARS 1027
G Q +S G HE R+ H + SS+ SG +SSG + Q RS
Sbjct: 973 GFGQHESGSGKSSGFGQHESRSSQSNYGQHGSGSSQSSGYGQHGSSSG--QTTGFGQHRS 1030
Query: 1028 SPGE-----RHGSRHQQSADSSRH-------SGIPRRQASSAVRDSGHWGSSGSQASDSE 1075
S G+ +HGS QS+ +H SG + ++ S G GS SQ+S
Sbjct: 1031 SSGQYSGFGQHGSGSDQSSGFGQHGTGSGQSSGFGQYESRSRQSSYGQHGSGSSQSSGYG 1090
Query: 1076 GHSEESDTQSVSGHGQDGPHQQSHQESARDWSGGRSGRSGSFIYQVSTHEQSESAHGRTR 1135
H S++ SG GQ P S Q S G SG+S F G+
Sbjct: 1091 QHG--SNSGQTSGFGQHRP--GSGQSSGFGQYGSGSGQSSGF--------------GQHG 1132
Query: 1136 TSTGRRQG-SHHEQARDSSRHSASQEGQDTIRAHPGSRRGGRQGSHHEQSVDRSGHSGSH 1194
+ TG+ G + HE S + G G + Q V S + S
Sbjct: 1133 SGTGKSSGFAQHEYRSGQSSYGQHGTGSSQSSGCGQHESGSGPTTSFGQHVSGSDNFSSS 1192
Query: 1195 HSHTTSQGRSD--ASHGQSGSRSASRQTRKDKQSGDGSRHSGSRHHEAASWADSSRHSQV 1252
H + G+S +G +S + +Q GS G + +++RHSQ
Sbjct: 1193 GQHISDSGQSTGFGQYGSGSGQSTGLGQGESQQVESGSTVHGRQETTHGQTINTTRHSQS 1252
Query: 1253 GQEQS--SGSRTSRHQGSSVSQDSDSERHSDDSER--------------LSGSASRNHHG 1296
GQ QS +GSR +R + SS S++SDSE HS S R SGS R G
Sbjct: 1253 GQGQSTQTGSRVTRRRRSSQSENSDSEVHSKVSHRHSEHIHTQAGSHYPKSGSTVRRRQG 1312
Query: 1297 SSREQSRDGSR--HPGFHQ----------EDRASHGHSADSSRQSGTH---HTESSSHGQ 1341
++ Q D +R H G Q R SH + DS SG H++ +H Q
Sbjct: 1313 TTHGQRGDTTRHGHSGHGQSTQTGSRTSGRQRFSHSDATDSEVHSGVSHRPHSQEQTHSQ 1372
Query: 1342 AVSSHEQARSSPGERHGSRHQQSADSSRHSGIGHRQASS-AVRDSGHRGSSGSQVTNSEG 1400
A S H ++ S+ ERH + + Q+ +++ H GH Q++ R +G RGS G
Sbjct: 1373 AGSQHGESESTVHERHETTYGQTGEATGHGHSGHGQSTQRGSRTTGRRGS---------G 1423
Query: 1401 HSEDSDTQSVSAHGQAGPHQQSHKESARGQSGESSGRSRSFLYQVSSHEQSESTHGQTAP 1460
HSE SD++ S G H+ +E GQ+G S HG++
Sbjct: 1424 HSESSDSEVHS----GGSHRPQSQEQTHGQAG--------------------SQHGESGS 1459
Query: 1461 STGGRQGSRHEQARNSSRHSASQDGQDTIRGHPGSSRGGRQGSYHEQSVDRSGHSGYHHS 1520
+ GR G+ H Q +++RH+ G+ T R GSS GR+GS H +S D HSG H+
Sbjct: 1460 TVHGRHGTTHGQTGDTTRHAHYHHGKSTQR---GSSTTGRRGSGHSESSDSEVHSGGSHT 1516
Query: 1521 HT-TPQGRSDASHGQSGPRSASRQTRNEEQSGDGSRHSGSRHHEPSTRAGSSRHSQVGQG 1579
H+ G+S + HG+S R Q+GD +RHS S H Q
Sbjct: 1517 HSGHTHGQSGSQHGESESIIHDRHRITHGQTGDTTRHSYSGHE---------------QT 1561
Query: 1580 ESAGSKTSRRQGSSVSQDRDSEGHSEDSERRSESASRNH-YGSAREQ---------SRHG 1629
GS+T+ RQ +S S+ DSE HS S R SR H YG A Q RHG
Sbjct: 1562 TQTGSRTTGRQRTSHSESTDSEVHSGGSHR---PHSREHTYGQAGSQHEEPEFTVHERHG 1618
Query: 1630 S---------------------RNPRSHQEDRASHGHSAESSRQSGTRHAETS-SGGQAA 1667
+ R R+ R+SH S++S SG H T + GQA
Sbjct: 1619 TTHGQIGDTTGHSHSGHGQSTQRGSRTTGRQRSSHSESSDSEVHSGVSHTHTGHTHGQAG 1678
Query: 1668 SSQEQARSSPGERHGSRHQQSADSS--------TDSGTGRRQDSSVVGDSGNRGSSGSQA 1719
S Q+ S ERHG+ H Q+ D++ + TG R +G RGS S+
Sbjct: 1679 SQHGQSESIVPERHGTTHGQTGDTTRHAHYHHGLTTQTGSR-------TTGRRGSGHSEY 1731
Query: 1720 SDSEGHSEESDTQSVSAHGQAGPHQQSHQESTRGQSGERSGRSGSFLYQVSTHEQSESAH 1779
SDSEG+S S T S HGQA + + G G++G T + S H
Sbjct: 1732 SDSEGYSGVSHTHSGHTHGQARSQHGESESIVHERHGTIHGQTG------DTTRHAHSGH 1785
Query: 1780 G---RTGPSTGGRQRSRHEQARDSSRHSASQE---GQDTIRGHPGSSRG-------GRQG 1826
G +TG T GR+ S H + DS HS + + G GS G R G
Sbjct: 1786 GQSTQTGSRTTGRRSSGHSEYSDSEGHSGFSQRPHSRGHTHGQAGSQHGESESIVDERHG 1845
Query: 1827 SHYEQSVDSSGHSGSHHSHTTSQERSDVSRGQSGSRSVSRQTRNEKQSGDGSRHSGSRHH 1886
+ + Q+ D+SGHS S H +T S R +SG S + +E SG HSG H
Sbjct: 1846 TTHGQTGDTSGHSQSGHGQSTQSGSSTTGRRRSGH---SESSDSEVHSGGSHTHSGHTHS 1902
Query: 1887 EASSR-------------------ADSSRHSQVGQGQS--SGPRTSRNQGSSVSQDSDSQ 1925
+A S+ D++ H GQ+ +G RT+ +GS S+ SDS+
Sbjct: 1903 QARSQHGESESTVHKRHQTTHGQTGDTTEHGHPSHGQTIQTGSRTTGRRGSGHSEYSDSE 1962
Query: 1926 G------------HSEDSERW--SGSASRNHLGSAWEQSRDGSRHPGSHH---------- 1961
G H + + SGS+ G+ Q+ D +RH S H
Sbjct: 1963 GPSGVSHTHSGHTHGQAGSHYPESGSSVHERHGTTHGQTADTTRHGHSGHGQSTQRGSRT 2022
Query: 1962 --EDRAGHGHSADSSRQSGTRHTESS-SRGQAASSHEQARSSAGERHGSHHQLQSADSSR 2018
+GH +DS SG HT S + GQA S H ++ SS ERHG+ H Q+ D++R
Sbjct: 2023 TGRRASGHSEYSDSEGHSGVSHTHSGHAHGQAGSQHGESGSSVHERHGTTHG-QTGDTTR 2081
Query: 2019 HSGIGHGQASS-AVRDSGHRGYSGSQASDSEGHSEDSDTQSVSAQGKAGPHQQSHKESAR 2077
H+ GHGQ++ R +G RG S++SDSE HS S T S G+A
Sbjct: 2082 HAHSGHGQSTQRGSRTAGRRGSGHSESSDSEVHSGVSHTHSGHTYGQA------------ 2129
Query: 2078 GQSGESSGRSGSFLYQVSTHEQSESTHGQSAPSTGGRQGSHYDQAQDSSRHSASQEGQDT 2137
S HG+S + GRQG+ + Q D++RH S GQ T
Sbjct: 2130 -----------------------RSQHGESGSAIHGRQGTIHGQTGDTTRHGQSGHGQST 2166
Query: 2138 IRGHPGPSRGGRQGSHQEQSVDRSGH---SGSHHSHTTSQGRSDASRGQSGSRSASRKTY 2194
G GRQ S +S D H S +H HT SQ S GQSGS R+
Sbjct: 2167 ---QTGSRTTGRQRSSHSESSDSEVHSEASPTHSGHTHSQAGS--RHGQSGSSGHGRQGT 2221
Query: 2195 DKEQSGDGSRHSGSHHHEASSWADSSRHSLVGQGQSSGPRTSRPRGSSVSQDSDSEGHSE 2254
Q+GD +RH+ H GQ G RT+ RGS S+ SDSE HS
Sbjct: 2222 THGQTGDTTRHA---------------HYGYGQSTQRGSRTTGRRGSGHSESSDSEVHS- 2265
Query: 2255 DSERRSGSASRNHHGSAQEQSRDGSRHPRS--HHEDRAGHGHSAESSRQSGTHHAENSSG 2312
S H G Q Q+ R P S H HG + +++R + + +++
Sbjct: 2266 -------WGSHTHSGHIQGQAGSQQRQPGSTVHGRLETTHGQTGDTTRHGHSGYGQSTQT 2318
Query: 2313 GQAAS--SHEQARSSAGERHGSHHQQSADSSRHSGIGHGQASSAVRDSGHRG---SSGSQ 2367
G +S SH Q+ SS +RHGS HG A D GH G S GS+
Sbjct: 2319 GSRSSRASHFQSHSSERQRHGSSQVWK----------HGSYGPAEYDYGHTGYGPSGGSR 2368
Query: 2368 ASDSEGH 2374
S S H
Sbjct: 2369 KSISNSH 2375
Score = 736 bits (1900), Expect = 0.0
Identities = 743/2543 (29%), Positives = 1040/2543 (40%), Gaps = 442/2543 (17%)
Query: 1613 SASRNHYGSAREQSRHGSRNPRSHQEDRASHGHSAESSRQSGTRHAETSSGGQAASSQEQ 1672
S S+ H R RH + +++ + GH +SG RH+ S G + S
Sbjct: 97 SGSKKH----RRGHRHQEEESETEEDEEDTPGH------KSGYRHSSWSEGEEHGYSSGH 146
Query: 1673 ARSSPGERHGSRHQQSADSSTDSGTGRRQDSSVVGDSGNRGSSGSQASDSEGHSEESDTQ 1732
+R + RHGS ++ S +G ++ S + G S S D G S +
Sbjct: 147 SRGTVKCRHGSNSRRLGRQGNLSSSGNQEGSQKRYHRSSCGHSWSGGKDRHGSSSVELRE 206
Query: 1733 SVSAHGQAGPHQQSHQESTRGQ---SGERSGRSG-SFLYQVSTHE----QSESAHGRTGP 1784
++ P ++S +E G S ER G G S + S HE QS + G
Sbjct: 207 RINK-SHISPSRESGEEYESGSGSNSWERKGHGGLSCGLETSGHESNSTQSRIREQKLGS 265
Query: 1785 STGGR----QRSRHEQARDSSRHSASQEGQDTIRGHPGSSRGGRQGSHYEQSVDSSGHSG 1840
S G +RS +SS Q + + H +G Q S+ + S G
Sbjct: 266 SCSGSGDSGRRSHACGYSNSSGCGRPQNASSSCQSHRFGGQGN-QFSYIQSGCQSGIKGG 324
Query: 1841 SHHSHTTSQERSDVSRGQSGSRSVSRQTRNEKQSGDGSRHSGSRHHEASS-RADSSRHSQ 1899
H + + S + +S S S R G G+R +G + R SS+ S
Sbjct: 325 QGHGCVSGGQPSGCGQPESNPCSQSYSQR-----GYGARENGQPQNCGGQWRTGSSQSSC 379
Query: 1900 VGQGQSSGPRTSRNQGSSVSQDSDSQGHSEDSERWSGSASRNHLGSAWEQSRDGSRHPGS 1959
GQ S G ++ N + S G +S + + + GS QS +H G+
Sbjct: 380 CGQYGSGGSQSCSNG----QHEYGSCGRFSNSSSSNEFSKCDQYGSGSSQSTSFEQH-GT 434
Query: 1960 HHEDRAGHGHSADSSRQSGTRHTESSSRGQAASSHEQARSSAGERHG-SHHQLQSADSSR 2018
+G S Q+ +H +SS+ + ++Q SS+G+ G H S SS
Sbjct: 435 GLSQSSGFEQHVCGSGQTCGQHESTSSQ---SLGYDQHGSSSGKTSGFGQHGSGSGQSS- 490
Query: 2019 HSGIGHGQASSAVRDSGHRGYSGSQASDSEGHSEDSDTQSVSAQGKA-GPHQQSHKESAR 2077
G GQ S S G GS + S G + SVS Q G H+ ++S+
Sbjct: 491 ----GFGQCGSGSGQSSGFGQHGSVSGQSSGFGQHG---SVSGQSSGFGQHESRSRQSSY 543
Query: 2078 GQSGESSGRSGSFLYQVSTHEQSESTHGQ-SAPSTG-GRQGSHYDQAQDSSRHSASQEGQ 2135
GQ G S +S + S HG S STG G+ GS Q+ +H +
Sbjct: 544 GQHGSGSSQSSGYGQYGSRETSGFGQHGLGSGQSTGFGQYGSGSGQSSGFGQHGS----- 598
Query: 2136 DTIRGHPGPSRGGRQGSHQEQSVDRSGHSGSHHSHTTSQGRSDASRGQSGSRSASRKTYD 2195
G Q S Q RSG S S+ H++ +S + GQ GSR
Sbjct: 599 -----------GSGQSSGFGQHESRSGQS-SYGQHSSGSSQS-SGYGQHGSR-------- 637
Query: 2196 KEQSGDGSRHSGSHHHEASSWADSSRHSLVGQGQSSGPRTSRPRGSSVSQDSDSEGHSED 2255
+ SG G SGS S G GQSSG G VS S G +
Sbjct: 638 -QTSGFGQHGSGSSQSTGFGQYGS------GSGQSSG------FGQHVSGSGQSSGFGQH 684
Query: 2256 SERRSGSASRNHHGSAQEQSRDGSRHPRSHHEDRAGHGHSAESSRQSGTHHAENSSGGQA 2315
E RSG +S HG QS +H S + +G G SS QS + S GQ+
Sbjct: 685 -ESRSGHSSYGQHGFGSSQSSGYGQHGSSSGQT-SGFGQHELSSGQSSSFGQHGSGSGQS 742
Query: 2316 ASSHEQARSSAGERHG--SHHQQSADSSRHSGIGHGQASSAVRDSGHRGSSGSQASDSEG 2373
S Q S +G+ G H +S SS +GQ SS S G GS+ + G
Sbjct: 743 -SGFGQHGSGSGQSSGFGQHESRSGQSS------YGQHSSGSSQSSGYGQHGSRQTSGFG 795
Query: 2374 HSEDSDTQSVSAHGQAGPHQQSHQESTRGRSAGRSGRSGSF-LYQVSTHEQSESAHGRTG 2432
+QS + GQ G S Q + G+ SG+S F ++ +H+ S HG
Sbjct: 796 QHGSGSSQS-TGFGQYG--SGSGQSAGFGQHGSGSGQSSGFGQHESRSHQSSYGQHGSGS 852
Query: 2433 TSTGG--RQGSHHKQARDSSRHSTSQEGQDTIHGHPGSSSGGRQGSHYEQLVDRSGHSGS 2490
+ + G + GS Q +H +S GQ + G GS SG Q S + Q SG
Sbjct: 853 SQSSGYGQHGSSSGQTSGFGQHRSSS-GQYSGFGQHGSGSG--QSSGFGQHGTGSGQYSG 909
Query: 2491 HHSHTTSQGRSDASHGHSGSRSASRQTRNDEQSGDGSRHSGSRHHEASSRADSSGHSQVG 2550
H + +S S+G GS S+ S G +H S ++ G G
Sbjct: 910 FGQHESRSHQS--SYGQHGSGSSQSSGYGQHGSSSGQTFGFGQHRSGSGQSSGFGQHGSG 967
Query: 2551 QGQSEGPRTSRNWGSSFSQDSDSQGHSEDSERWSGSASRNHHGSAQEQLRDGSRHPRSHQ 2610
GQS G +G S S G + R S ++ HGS Q +H S
Sbjct: 968 SGQSSG------FGQHESGSGKSSGFGQHESR-SSQSNYGQHGSGSSQSSGYGQHGSSSG 1020
Query: 2611 EDRAGHGHSADSSRQSGTRHTQTSSGGQAASSHEQARSSAGERHGSHHQQSADSSRHSGI 2670
+ H + S + SG Q SG +S Q + +G+ G +S SR S
Sbjct: 1021 QTTGFGQHRSSSGQYSG--FGQHGSGSDQSSGFGQHGTGSGQSSGFGQYESR--SRQSSY 1076
Query: 2671 G-HGQASSAVRDSGHRGYSGSQASDNEGHSEDSDTQSVSAHGQAGSHQQSHQESARGRSG 2729
G HG SS G G + Q S H S S GQ GS S Q S G+ G
Sbjct: 1077 GQHGSGSSQSSGYGQHGSNSGQTSGFGQHRPGSGQSS--GFGQYGSG--SGQSSGFGQHG 1132
Query: 2730 ETSGHSGSFLYQVSTHEQSESSHGWTGPSTRGRQGSRHEQAQDSSRHSASQDGQDTIRGH 2789
+G S F + HE +G S+ G+ G+ Q+ +H + + H
Sbjct: 1133 SGTGKSSGF----AQHEYR------SGQSSYGQHGTGSSQSSGCGQHESGSGPTTSFGQH 1182
Query: 2790 -PGSSRGGRQGYHHEHSVDSSGHS--GSHHSHTTSQGRSDASRGQSGSRSASRTTRNEEQ 2846
GS G H S S+G GS +T G+ ++ + +SGS R Q
Sbjct: 1183 VSGSDNFSSSGQHISDSGQSTGFGQYGSGSGQSTGLGQGESQQVESGSTVHGRQETTHGQ 1242
Query: 2847 SGDGSRHSGSRHHEASTHADISRHSQAVQGQSE--GSRRSRRQGSSVSQDSDSEGHSEDS 2904
+ + +RHSQ+ QGQS GSR +RR+ SS S++SDSE HS+ S
Sbjct: 1243 T-----------------INTTRHSQSGQGQSTQTGSRVTRRRRSSQSENSDSEVHSKVS 1285
Query: 2905 ERWS--------------GSASRNHHGSAQEQLRDGSRH------------PRSHQEDRA 2938
R S GS R G+ Q D +RH R+ R
Sbjct: 1286 HRHSEHIHTQAGSHYPKSGSTVRRRQGTTHGQRGDTTRHGHSGHGQSTQTGSRTSGRQRF 1345
Query: 2939 GHGHSADSSRQSGTRH---TQTSSGGQAASSHEQARSSAGERHGSHHQQSADSSRHSGIG 2995
H + DS SG H +Q + QA S H ++ S+ ERH + + Q+ +++ H G
Sbjct: 1346 SHSDATDSEVHSGVSHRPHSQEQTHSQAGSQHGESESTVHERHETTYGQTGEATGHGHSG 1405
Query: 2996 HGQASS-AVRDSGHRGYSGSQASDNEGHSEDSDTQSVSAHGQAGSHQQSHQESARGRSGE 3054
HGQ++ R +G RG S++SD+E HS GSH+ QE
Sbjct: 1406 HGQSTQRGSRTTGRRGSGHSESSDSEVHS-------------GGSHRPQSQEQ------- 1445
Query: 3055 TSGHSGSFLYQVSTHEQSESSHGWTGPSTRGRQGSRHEQAQDSSRHSASQYGQDTIRGHP 3114
TH Q+ S HG +G + GR G+ H Q D++RH+ +G+ T RG
Sbjct: 1446 -------------THGQAGSQHGESGSTVHGRHGTTHGQTGDTTRHAHYHHGKSTQRG-- 1490
Query: 3115 GSSRGGRQGYHHEHSVDSSGHSGSHHSHTT-SQGRSDASRGQSGSRSASRTTRNEEQSGD 3173
SS GR+G H S DS HSG H+H+ + G+S + G+S S R Q+GD
Sbjct: 1491 -SSTTGRRGSGHSESSDSEVHSGGSHTHSGHTHGQSGSQHGESESIIHDRHRITHGQTGD 1549
Query: 3174 SSRHSVSRHHEASTHADISRHSQAVQGQSEGSRRSRRQGSSVSQDSDSEGHSEDSER--- 3230
++RHS S H + + GSR + RQ +S S+ +DSE HS S R
Sbjct: 1550 TTRHSYSGHEQTT---------------QTGSRTTGRQRTSHSESTDSEVHSGGSHRPHS 1594
Query: 3231 ----WSGSASRNHRGSVQEQSRHGSRH---------------------PRSHHEDRAGHG 3265
+ + S++ RHG+ H R+ R+ H
Sbjct: 1595 REHTYGQAGSQHEEPEFTVHERHGTTHGQIGDTTGHSHSGHGQSTQRGSRTTGRQRSSHS 1654
Query: 3266 HSADRSRQSGTRHAETS-SGGQAASSHEQARSSPGERHGSRHQQSADSSRHSGIPRGQAS 3324
S+D SG H T + GQA S H Q+ S ERHG+ H Q+ D++RH+ G +
Sbjct: 1655 ESSDSEVHSGVSHTHTGHTHGQAGSQHGQSESIVPERHGTTHGQTGDTTRHAHYHHGLTT 1714
Query: 3325 SAVRDSRHWGSSGSQASDSEGHSEESDTQSVSGHGQAGPHQQSHQESARDRSGGRSGRSG 3384
SR G GS GHSE SD++ SG SH S
Sbjct: 1715 QT--GSRTTGRRGS------GHSEYSDSEGYSG--------VSHTHSGH----------- 1747
Query: 3385 SFLYQVSTHEQSESAHGRTRTSTGRRQGSHHEQARDSSRHSASQEGQDTIRGHPGSSRRG 3444
TH Q+ S HG + + R G+ H Q D++RH+ S GQ T GS G
Sbjct: 1748 -------THGQARSQHGESESIVHERHGTIHGQTGDTTRHAHSGHGQST---QTGSRTTG 1797
Query: 3445 RQGSHYEQSVDRSGHSG-SHHSHTTSQGRSDASRGQSGSRSASRQTRNDEQSGDGSRHSW 3503
R+ S + + D GHSG S H+ + GQ+GS+ ++ DE RH
Sbjct: 1798 RRSSGHSEYSDSEGHSGFSQRPHSRGH-----THGQAGSQHGESESIVDE------RHGT 1846
Query: 3504 SHHHEASTQADSSRHSQSGQGQS--AGPRTSRNQGSSVSQDSDSQGHSEDSERWSG---S 3558
+H D+S HSQSG GQS +G T+ + S S+ SDS+ HS S SG S
Sbjct: 1847 TH----GQTGDTSGHSQSGHGQSTQSGSSTTGRRRSGHSESSDSEVHSGGSHTHSGHTHS 1902
Query: 3559 ASRNHRGSAQEQSRDGSRHPTSHHED-----------------------RAGHGHS--AE 3593
+R+ G + +S RH T+H + R G GHS ++
Sbjct: 1903 QARSQHG--ESESTVHKRHQTTHGQTGDTTEHGHPSHGQTIQTGSRTTGRRGSGHSEYSD 1960
Query: 3594 SSRQSGTHHAENS-SGGQAASSHEQARSSAGERHGSHHQQSADSSRHSGIGHGQASS-AV 3651
S SG H + + GQA S + ++ SS ERHG+ H Q+AD++RH GHGQ++
Sbjct: 1961 SEGPSGVSHTHSGHTHGQAGSHYPESGSSVHERHGTTHGQTADTTRHGHSGHGQSTQRGS 2020
Query: 3652 RDSGHRGSSGSQASDSEGHSEDSDTQSVSAHGQAGP------------------------ 3687
R +G R S S+ SDSEGHS S T S AHGQAG
Sbjct: 2021 RTTGRRASGHSEYSDSEGHSGVSHTHSGHAHGQAGSQHGESGSSVHERHGTTHGQTGDTT 2080
Query: 3688 ---HQQSHQESTRG-RSAGRSG-----------RSG-SFLYQVSTHEQSESAHGRAGPST 3731
H Q + RG R+AGR G SG S + T+ Q+ S HG +G +
Sbjct: 2081 RHAHSGHGQSTQRGSRTAGRRGSGHSESSDSEVHSGVSHTHSGHTYGQARSQHGESGSAI 2140
Query: 3732 GGRQGSRHEQARDSSRHSASQEGQDTIRGHPGSRRGGRQGSYHEQSVDRSGHSGS---HH 3788
GRQG+ H Q D++RH S GQ T GSR GRQ S H +S D HS + H
Sbjct: 2141 HGRQGTIHGQTGDTTRHGQSGHGQST---QTGSRTTGRQRSSHSESSDSEVHSEASPTHS 2197
Query: 3789 SHTTSQGRSDASHGQSGSRSASRETRNEEQSGDGSRHSGSRHHEASTQADSSRHSQSGQG 3848
HT SQ S HGQSGS R+ Q+GD +RH+ H GQ
Sbjct: 2198 GHTHSQAGS--RHGQSGSSGHGRQGTTHGQTGDTTRHA---------------HYGYGQS 2240
Query: 3849 ESAGSRRSRRQGSSVSQDSDSEAYPEDSERRSESASRNHHGSSREQSRDGSRHPGSSHRD 3908
GSR + R+GS S+ SDSE + S H G + Q+ R PGS+
Sbjct: 2241 TQRGSRTTGRRGSGHSESSDSEVH--------SWGSHTHSGHIQGQAGSQQRQPGST--- 2289
Query: 3909 TASHVQSSPVQSDSSTAKEHGHFSSLSQDSAYHSGIQSRGSPHSSSSYHYQSEGTERQKG 3968
H + + HGH S Y Q+ SS + H+QS +ERQ+
Sbjct: 2290 --VHGRLETTHGQTGDTTRHGH-------SGYGQSTQT--GSRSSRASHFQSHSSERQRH 2338
Query: 3969 QSGLVWRHGSYGSADYDYGESGF 3991
S VW+HGSYG A+YDYG +G+
Sbjct: 2339 GSSQVWKHGSYGPAEYDYGHTGY 2361
Score = 662 bits (1708), Expect = 0.0
Identities = 722/2501 (28%), Positives = 991/2501 (39%), Gaps = 415/2501 (16%)
Query: 1511 RSGHSGYHHSHTTPQGRSDASHGQSGPRSASRQTRNEEQSGDGSRHSGS----RHHEPST 1566
R GH T + D +SG R +S E+ G S HS RH S
Sbjct: 103 RRGHRHQEEESETEEDEEDTPGHKSGYRHSSWS--EGEEHGYSSGHSRGTVKCRHGSNSR 160
Query: 1567 RAGSSRHSQVGQGESAGSKTSRRQGSSVSQDRDSEGHSEDSERRSESASRNHYGSAREQS 1626
R G + + K R S + H S E +++H +RE
Sbjct: 161 RLGRQGNLSSSGNQEGSQKRYHRSSCGHSWSGGKDRHGSSSVELRERINKSHISPSRESG 220
Query: 1627 RHGSRNPRSHQEDRASHGHSAESSRQSGTRHAETSSGGQAASSQEQARSSPGERHGSRHQ 1686
S+ +R HG + SG E++S Q+ S G R
Sbjct: 221 EEYESGSGSNSWERKGHGGLSCGLETSGH---ESNSTQSRIREQKLGSSCSGSGDSGRRS 277
Query: 1687 QSADSSTDSGTGRRQDSSVVGDSGNRGSSGSQAS-----------DSEGHSEESDTQSVS 1735
+ S SG GR Q++S S G G+Q S +GH S Q S
Sbjct: 278 HACGYSNSSGCGRPQNASSSCQSHRFGGQGNQFSYIQSGCQSGIKGGQGHGCVSGGQP-S 336
Query: 1736 AHGQAGPHQQSHQESTRGQSGERSGRSGSFLYQVSTHEQSESAHGRTGPSTGGRQ---RS 1792
GQ + S S RG +G+ + Q T S G+ G +GG Q
Sbjct: 337 GCGQPESNPCSQSYSQRGYGARENGQPQNCGGQWRTGSSQSSCCGQYG--SGGSQSCSNG 394
Query: 1793 RHEQARDS--SRHSASQEGQDTIRGHPGSSR---------GGRQGSHYEQSVDSSGHSGS 1841
+HE S S+S E + GSS+ G Q S +EQ V SG +
Sbjct: 395 QHEYGSCGRFSNSSSSNEFSKCDQYGSGSSQSTSFEQHGTGLSQSSGFEQHVCGSGQTCG 454
Query: 1842 HHSHTTSQERSDVSRGQSGSRSVSRQTRNEKQSGDGSRHSGSRHHEASSRADSSRHSQVG 1901
H T+SQ S G S S +T Q G GS S S SS Q G
Sbjct: 455 QHESTSSQ-----SLGYDQHGSSSGKTSGFGQHGSGSGQSSGFGQCGSGSGQSSGFGQHG 509
Query: 1902 Q--GQSSGPRTSRNQGSSVSQDSDSQGHSEDSERWSGSASRNHLGSAWEQSRD----GSR 1955
GQSSG Q SVS S G E R S S GS QS GSR
Sbjct: 510 SVSGQSSG----FGQHGSVSGQSSGFGQHESRSRQS---SYGQHGSGSSQSSGYGQYGSR 562
Query: 1956 HPGSHHEDRAGHGHSADSSRQSGTRHTESSSRGQAASSHEQARSSAGERHGSHHQLQSAD 2015
+ G G S Q G+ +SS GQ S Q+ S G+ H+ +S
Sbjct: 563 ETSGFGQHGLGSGQSTGFG-QYGSGSGQSSGFGQHGSGSGQS-SGFGQ-----HESRSGQ 615
Query: 2016 SSRHSGIGHGQASSAVRDSGHRGYSGSQASDSEGHSEDSDTQSVSAQGKAGPHQQSHKES 2075
SS +GQ SS S G GS+ + G +QS
Sbjct: 616 SS------YGQHSSGSSQSSGYGQHGSRQTSGFGQHGSGSSQSTGF-------------- 655
Query: 2076 ARGQSGESSGRSGSFLYQVSTHEQSESTHGQSAPSTGGRQGSHYDQAQDSSRHSASQEGQ 2135
GQ G SG+S F VS G Q S + Q + S HS+ GQ
Sbjct: 656 --GQYGSGSGQSSGFGQHVS----------------GSGQSSGFGQHESRSGHSSY--GQ 695
Query: 2136 DTIRGHPGPSRGGRQGSHQEQSVDRSGHSGSHHSHTTSQGRSDASRGQSGSRSASRKTYD 2195
G Q S Q SG + H S G+S +S GQ GS S +
Sbjct: 696 HGF--------GSSQSSGYGQHGSSSGQTSGFGQHELSSGQS-SSFGQHGSGSGQSSGFG 746
Query: 2196 KEQSGDGSRHSGSHHHEASSWADSSRHSLVGQGQSSG-----PRTSRPRGSSVSQDSDSE 2250
+ SG G + SG HE+ S S G QSSG R + G S S S
Sbjct: 747 QHGSGSG-QSSGFGQHESRSGQSSYGQHSSGSSQSSGYGQHGSRQTSGFGQHGSGSSQST 805
Query: 2251 GHSEDSERRSGSASRNHHGSAQEQSRDGSRHP-RSHHEDRAGHGHSAESSRQSGTHHAEN 2309
G + SA HGS QS +H RSH HG + S G H
Sbjct: 806 GFGQYGSGSGQSAGFGQHGSGSGQSSGFGQHESRSHQSSYGQHGSGSSQSSGYGQH---G 862
Query: 2310 SSGGQAASSHEQARSSAGERHGSHHQQSADSSRHSGIG-HGQASSAVRDSGHRGSSGSQA 2368
SS GQ S Q RSS+G+ G Q + S + SG G HG S G S Q+
Sbjct: 863 SSSGQT-SGFGQHRSSSGQYSG-FGQHGSGSGQSSGFGQHGTGSGQYSGFGQHESRSHQS 920
Query: 2369 SDSEGHSEDSDTQSVSAHGQA-------GPHQQ-SHQESTRGRSAGRSGRSGSFLYQVST 2420
S + S S + HG + G H+ S Q S G+ SG+S F S
Sbjct: 921 SYGQHGSGSSQSSGYGQHGSSSGQTFGFGQHRSGSGQSSGFGQHGSGSGQSSGFGQHESG 980
Query: 2421 HEQSESA---HGRTGTSTGGRQGSHHKQARDSSRHSTSQEGQDTIHGHPGSSSGGRQGSH 2477
+S R+ S G+ GS Q+ +H +S GQ T G SSSG Q S
Sbjct: 981 SGKSSGFGQHESRSSQSNYGQHGSGSSQSSGYGQHGSSS-GQTTGFGQHRSSSG--QYSG 1037
Query: 2478 YEQLVDRSGHSGSHHSHTTSQGRSDASHGHSGSRSASRQTRNDEQSGDGSRHSGSRHHEA 2537
+ Q S S H T G+S G S SRQ+ + S+ SG H +
Sbjct: 1038 FGQHGSGSDQSSGFGQHGTGSGQSS---GFGQYESRSRQSSYGQHGSGSSQSSGYGQHGS 1094
Query: 2538 SSRADSS-GHSQVGQGQSEG-------PRTSRNWGSSFSQDSDSQGHSEDSERWSGSASR 2589
+S S G + G GQS G S +G S S G ++ R SG +S
Sbjct: 1095 NSGQTSGFGQHRPGSGQSSGFGQYGSGSGQSSGFGQHGSGTGKSSGFAQHEYR-SGQSSY 1153
Query: 2590 NHHGSAQEQLRDGSRHPR------------SHQEDRAGHG-HSADSSRQSGTRHTQTSSG 2636
HG+ Q +H S ++ + G H +DS + +G + SG
Sbjct: 1154 GQHGTGSSQSSGCGQHESGSGPTTSFGQHVSGSDNFSSSGQHISDSGQSTGFGQYGSGSG 1213
Query: 2637 -----GQAASSHEQARSSAGERHGSHHQQSADSSRHSGIGHGQAS-SAVRDSGHRGYSGS 2690
GQ S ++ S+ R + H Q+ +++RHS G GQ++ + R + R S S
Sbjct: 1214 QSTGLGQGESQQVESGSTVHGRQETTHGQTINTTRHSQSGQGQSTQTGSRVTRRRRSSQS 1273
Query: 2691 QASDNEGHSEDSDTQSVSAHGQAGSHQQSHQESARGRSGETSGHSGSFLYQVSTHEQSES 2750
+ SD+E HS+ S S H QAGSH
Sbjct: 1274 ENSDSEVHSKVSHRHSEHIHTQAGSHYPK------------------------------- 1302
Query: 2751 SHGWTGPSTRGRQGSRHEQAQDSSRHSASQDGQDTIRGHPGSSRGGRQGYHHEHSVDSSG 2810
+G + R RQG+ H Q D++RH S GQ T GS GRQ + H + DS
Sbjct: 1303 ----SGSTVRRRQGTTHGQRGDTTRHGHSGHGQST---QTGSRTSGRQRFSHSDATDSEV 1355
Query: 2811 HSG-SHHSHTTSQGRSDASRGQSGSRSASRTTRNEEQSGDGSRHSGSRHHEASTHADISR 2869
HSG SH H+ Q S A Q G ++ R+E G +G H S
Sbjct: 1356 HSGVSHRPHSQEQTHSQAG-SQHGESESTVHERHETTYGQTGEATGHGH---------SG 1405
Query: 2870 HSQAVQGQSEGSRRSRRQGSSVSQDSDSEGHSEDSER----------------WSGSASR 2913
H Q+ Q GSR + R+GS S+ SDSE HS S R SGS
Sbjct: 1406 HGQSTQ---RGSRTTGRRGSGHSESSDSEVHSGGSHRPQSQEQTHGQAGSQHGESGSTVH 1462
Query: 2914 NHHGSAQEQLRDGSR-----HPRSHQEDRA-------GHGHSADSSRQSGTRHTQTS-SG 2960
HG+ Q D +R H +S Q + GH S+DS SG HT + +
Sbjct: 1463 GRHGTTHGQTGDTTRHAHYHHGKSTQRGSSTTGRRGSGHSESSDSEVHSGGSHTHSGHTH 1522
Query: 2961 GQAASSHEQARSSAGERHGSHHQQSADSSRHSGIGHGQAS-SAVRDSGHRGYSGSQASDN 3019
GQ+ S H ++ S +RH H Q+ D++RHS GH Q + + R +G + S S+++D+
Sbjct: 1523 GQSGSQHGESESIIHDRHRITHGQTGDTTRHSYSGHEQTTQTGSRTTGRQRTSHSESTDS 1582
Query: 3020 EGHSEDSDTQSVSAHGQAGSHQQSHQESARGRSGETSGHSGSFLYQVSTHEQSESSHGWT 3079
E HS GSH+ +E G++G S HE+ E +
Sbjct: 1583 EVHS-------------GGSHRPHSREHTYGQAG-------------SQHEEPEFT---- 1612
Query: 3080 GPSTRGRQGSRHEQAQDSSRHSASQYGQDTIRGHPGSSRGGRQGYHHEHSVDSSGHSGSH 3139
R G+ H Q D++ HS S +GQ T RG S GRQ H S DS HSG
Sbjct: 1613 ---VHERHGTTHGQIGDTTGHSHSGHGQSTQRG---SRTTGRQRSSHSESSDSEVHSGVS 1666
Query: 3140 HSHTT-SQGRSDASRGQSGSRSASRTTRNEEQSGDSSRHSVSRHHEASTHADISRHSQAV 3198
H+HT + G++ + GQS S R Q+GD++RH+ HH +T
Sbjct: 1667 HTHTGHTHGQAGSQHGQSESIVPERHGTTHGQTGDTTRHA-HYHHGLTTQT--------- 1716
Query: 3199 QGQSEGSRRSRRQGSSVSQDSDSEGHSEDSERWSGSA---SRNHRGSVQE--QSRHGSRH 3253
GSR + R+GS S+ SDSEG+S S SG +R+ G + RHG+ H
Sbjct: 1717 -----GSRTTGRRGSGHSEYSDSEGYSGVSHTHSGHTHGQARSQHGESESIVHERHGTIH 1771
Query: 3254 PRSHHEDR---AGHGHSADR-SRQSGTR--------------------HAETSSGGQAAS 3289
++ R +GHG S SR +G R H+ + GQA S
Sbjct: 1772 GQTGDTTRHAHSGHGQSTQTGSRTTGRRSSGHSEYSDSEGHSGFSQRPHSRGHTHGQAGS 1831
Query: 3290 SHEQARSSPGERHGSRHQQSADSSRHSGIPRGQASSAVRDSRHWGSSG-SQASDSEGHSE 3348
H ++ S ERHG+ H Q+ D+S HS GQ++ + + SG S++SDSE HS
Sbjct: 1832 QHGESESIVDERHGTTHGQTGDTSGHSQSGHGQSTQSGSSTTGRRRSGHSESSDSEVHSG 1891
Query: 3349 ESDTQSVSGHGQAGP------------HQQSHQESARDRSGGR-------------SGRS 3383
S T S H QA HQ +H ++ G +GR
Sbjct: 1892 GSHTHSGHTHSQARSQHGESESTVHKRHQTTHGQTGDTTEHGHPSHGQTIQTGSRTTGRR 1951
Query: 3384 GSFLYQVS---------------THEQSESAHGRTRTSTGRRQGSHHEQARDSSRHSASQ 3428
GS + S TH Q+ S + + +S R G+ H Q D++RH S
Sbjct: 1952 GSGHSEYSDSEGPSGVSHTHSGHTHGQAGSHYPESGSSVHERHGTTHGQTADTTRHGHSG 2011
Query: 3429 EGQDTIRGHPGSSRRGRQGSHYEQSVDRSGHSGSHHSHTT-SQGRSDASRGQSGSRSASR 3487
GQ T RG S GR+ S + + D GHSG H+H+ + G++ + G+SGS R
Sbjct: 2012 HGQSTQRG---SRTTGRRASGHSEYSDSEGHSGVSHTHSGHAHGQAGSQHGESGSSVHER 2068
Query: 3488 QTRNDEQSGDGSRHSWSHHHEASTQADSSRHSQSGQGQSAGPRTSRNQGSSVSQDSDSQG 3547
Q+GD +RH+ S H + STQ S + G G S + + G S + + G
Sbjct: 2069 HGTTHGQTGDTTRHAHSGHGQ-STQRGSRTAGRRGSGHSESSDSEVHSGVSHTHSGHTYG 2127
Query: 3548 HSEDSERWSGSASRNHRGSAQEQSRDGSRHPTSHH------------EDRAGHGHSAES- 3594
+ SGSA +G+ Q+ D +RH S H R+ H S++S
Sbjct: 2128 QARSQHGESGSAIHGRQGTIHGQTGDTTRHGQSGHGQSTQTGSRTTGRQRSSHSESSDSE 2187
Query: 3595 --SRQSGTHHAENSSGGQAASSHEQARSSAGERHGSHHQQSADSSRHSGIGHGQASS-AV 3651
S S TH S QA S H Q+ SS R G+ H Q+ D++RH+ G+GQ++
Sbjct: 2188 VHSEASPTHSGHTHS--QAGSRHGQSGSSGHGRQGTTHGQTGDTTRHAHYGYGQSTQRGS 2245
Query: 3652 RDSGHRGSSGSQASDSEGHSEDSDTQSVSAHGQAGPHQQSHQESTRGRSAGRSGRSGSFL 3711
R +G RGS S++SDSE HS S T S GQAG Q+ + GR G++G
Sbjct: 2246 RTTGRRGSGHSESSDSEVHSWGSHTHSGHIQGQAGSQQRQPGSTVHGRLETTHGQTGD-- 2303
Query: 3712 YQVSTHEQSESAHGRAGPSTGGRQGSRHEQARDSSRHSASQEGQDTIRGHPGSRRGGRQG 3771
+ HG +G + GSR +A HS+ R GS + + G
Sbjct: 2304 ---------TTRHGHSGYGQSTQTGSRSSRASHFQSHSSE-------RQRHGSSQVWKHG 2347
Query: 3772 SYHEQSVDRSGHSGSHHSHTTSQGRSDASHGQSGSRSASRE 3812
SY D GH+G S + + S++ S +A+++
Sbjct: 2348 SYGPAEYD-YGHTGYGPSGGSRKSISNSHLSWSTDSTANKQ 2387
Score = 499 bits (1284), Expect = e-140
Identities = 470/1553 (30%), Positives = 654/1553 (42%), Gaps = 303/1553 (19%)
Query: 299 QDRDSEGHSEDSERHSGSASRNHHGSAWEQSRDGSRHPRSHDEDRAS---HGHSADSSRQ 355
Q R G S +H GS S G +S G E R+S +G S Q
Sbjct: 950 QHRSGSGQSSGFGQH-GSGSGQSSGFGQHESGSGKSSGFGQHESRSSQSNYGQHGSGSSQ 1008
Query: 356 SGTRHAETSSRGQTASSHEQARSSPGE-----RHGSGHQQSADSSRHSATGRGQAS---- 406
S SS GQT + Q RSS G+ +HGSG QS+ +H TG GQ+S
Sbjct: 1009 SSGYGQHGSSSGQT-TGFGQHRSSSGQYSGFGQHGSGSDQSSGFGQHG-TGSGQSSGFGQ 1066
Query: 407 ----SAVSDRGHRGSSGSQASDSEGHSENSDTQSVSGHGKAGLRQQSHQESTRGRSGERS 462
S S G GS SQ+S H NS S G + G Q S SG+ S
Sbjct: 1067 YESRSRQSSYGQHGSGSSQSSGYGQHGSNSGQTSGFGQHRPGSGQSSGFGQYGSGSGQSS 1126
Query: 463 G--RSGSSLYQVSTHEQPDSAHGRTGTSTGGRQGSHHEQARDSSRHSASQEGQDTIRGH- 519
G + GS + S Q + R+G S+ G+ G+ Q+ +H + + H
Sbjct: 1127 GFGQHGSGTGKSSGFAQHEY---RSGQSSYGQHGTGSSQSSGCGQHESGSGPTTSFGQHV 1183
Query: 520 PGSSRGGRQGSHHEQSVNRSGHS--GSHHSHTTSQGRSDASHGQSGSRSASRQTRNEEQS 577
GS G H S +G GS +T G+ ++ +SGS RQ Q+
Sbjct: 1184 SGSDNFSSSGQHISDSGQSTGFGQYGSGSGQSTGLGQGESQQVESGSTVHGRQETTHGQT 1243
Query: 578 GDGTRHSGSRHHEASSQADSSRHSQVGQGQSS--GPRTSRNQGSSVSQDSDSQGHSEDSE 635
+++RHSQ GQGQS+ G R +R + SS S++SDS+ HS+ S
Sbjct: 1244 -----------------INTTRHSQSGQGQSTQTGSRVTRRRRSSQSENSDSEVHSKVSH 1286
Query: 636 RWS--------------GSASRNHHGSAQEQSRDGSRHPRSHH------------EDRAG 669
R S GS R G+ Q D +RH S H R
Sbjct: 1287 RHSEHIHTQAGSHYPKSGSTVRRRQGTTHGQRGDTTRHGHSGHGQSTQTGSRTSGRQRFS 1346
Query: 670 HGHSADSSRKSGTRH---TQNSSSGQAASSHEQARSSAGERHGSRHQLQSADSSRHSGTG 726
H + DS SG H +Q + QA S H ++ S+ ERH + + Q+ +++ H +G
Sbjct: 1347 HSDATDSEVHSGVSHRPHSQEQTHSQAGSQHGESESTVHERHETTYG-QTGEATGHGHSG 1405
Query: 727 HGQASS-AVRDSGHRGSSGSQATDSEGHSEDSDTQSVSGHGQAGHHQQSHQESARDRSGE 785
HGQ++ R +G RGS S+++DSE HS G H+ QE
Sbjct: 1406 HGQSTQRGSRTTGRRGSGHSESSDSEVHS-------------GGSHRPQSQEQ------- 1445
Query: 786 RSRRSGSFLYQVSTHKQSESSHGWTGPSTGVRQGSHHEQARDNSRHSASQDGQDTIRGHP 845
TH Q+ S HG +G + R G+ H Q D +RH+ G+ T RG
Sbjct: 1446 -------------THGQAGSQHGESGSTVHGRHGTTHGQTGDTTRHAHYHHGKSTQRG-- 1490
Query: 846 GSSRRGRQGSHHEQSVDRSGHSGSHHSHTT-SQGRSDASRGQSGSRSASRTTRNEEQSRD 904
SS GR+GS H +S D HSG H+H+ + G+S + G+S S R Q+ D
Sbjct: 1491 -SSTTGRRGSGHSESSDSEVHSGGSHTHSGHTHGQSGSQHGESESIIHDRHRITHGQTGD 1549
Query: 905 GSRHSGSRHHEASSHADISRHSQAGQGQSEGSRTSRRQGSSVSQDSDSEGHSEDSERWSG 964
+RHS S H + + GSRT+ RQ +S S+ +DSE HS S R
Sbjct: 1550 TTRHSYSGHEQTTQ---------------TGSRTTGRQRTSHSESTDSEVHSGGSHR--- 1591
Query: 965 SASRNHR----GSAQEQ------SRHGSRH---------------------PRSHHEDRA 993
SR H GS E+ RHG+ H R+ R+
Sbjct: 1592 PHSREHTYGQAGSQHEEPEFTVHERHGTTHGQIGDTTGHSHSGHGQSTQRGSRTTGRQRS 1651
Query: 994 GHGHSADSSRQSGTPHAETS-SGGQAASSHEQARSSPGERHGSRHQQSADSSRHS----G 1048
H S+DS SG H T + GQA S H Q+ S ERHG+ H Q+ D++RH+ G
Sbjct: 1652 SHSESSDSEVHSGVSHTHTGHTHGQAGSQHGQSESIVPERHGTTHGQTGDTTRHAHYHHG 1711
Query: 1049 IPRRQASSAVRDSGHWGSSGSQASDSEGHSEESDTQSVSGHGQ----------------- 1091
+ + S R +G GS S+ SDSEG+S S T S HGQ
Sbjct: 1712 LTTQTGS---RTTGRRGSGHSEYSDSEGYSGVSHTHSGHTHGQARSQHGESESIVHERHG 1768
Query: 1092 -------------DGPHQQSHQESARDW------------SGGRSGRSGSFIYQVSTHEQ 1126
H QS Q +R S G SG S + TH Q
Sbjct: 1769 TIHGQTGDTTRHAHSGHGQSTQTGSRTTGRRSSGHSEYSDSEGHSGFSQRPHSRGHTHGQ 1828
Query: 1127 SESAHGRTRTSTGRRQGSHHEQARDSSRHSASQEGQDTIRAHPGSRRGGRQGSHHEQSVD 1186
+ S HG + + R G+ H Q D+S HS S GQ T GS GR+ S H +S D
Sbjct: 1829 AGSQHGESESIVDERHGTTHGQTGDTSGHSQSGHGQST---QSGSSTTGRRRSGHSESSD 1885
Query: 1187 RSGHSGSHHSH---TTSQGRSDASHGQSGSRSASRQTRKDKQSGDGSRHSGSRHHEAASW 1243
HSG H+H T SQ RS HG+S S R Q+GD + H H
Sbjct: 1886 SEVHSGGSHTHSGHTHSQARSQ--HGESESTVHKRHQTTHGQTGDTTEHGHPSH------ 1937
Query: 1244 ADSSRHSQVGQEQSSGSRTSRHQGSSVSQDSDSERHSDDSERLSG--------------S 1289
GQ +GSRT+ +GS S+ SDSE S S SG S
Sbjct: 1938 ---------GQTIQTGSRTTGRRGSGHSEYSDSEGPSGVSHTHSGHTHGQAGSHYPESGS 1988
Query: 1290 ASRNHHGSSREQSRDGSRHP----------GFHQEDRASHGHS--ADSSRQSGTHHTESS 1337
+ HG++ Q+ D +RH G R + GHS +DS SG HT S
Sbjct: 1989 SVHERHGTTHGQTADTTRHGHSGHGQSTQRGSRTTGRRASGHSEYSDSEGHSGVSHTHSG 2048
Query: 1338 -SHGQAVSSHEQARSSPGERHGSRHQQSADSSRHSGIGHRQASS-AVRDSGHRGSSGSQV 1395
+HGQA S H ++ SS ERHG+ H Q+ D++RH+ GH Q++ R +G RGS S+
Sbjct: 2049 HAHGQAGSQHGESGSSVHERHGTTHGQTGDTTRHAHSGHGQSTQRGSRTAGRRGSGHSES 2108
Query: 1396 TNSEGHSEDSDT-------QSVSAHGQAGPHQQSHKESARGQSGESSGRSRSFLYQVSSH 1448
++SE HS S T Q+ S HG++G + + GQ+G+++ +S H
Sbjct: 2109 SDSEVHSGVSHTHSGHTYGQARSQHGESGSAIHGRQGTIHGQTGDTTRHGQS------GH 2162
Query: 1449 EQSESTHGQTAPSTGGRQGSRHEQARNS----------SRHSASQDGQDTIRGHPGSSRG 1498
QS QT T GRQ S H ++ +S S H+ SQ G G GSS
Sbjct: 2163 GQST----QTGSRTTGRQRSSHSESSDSEVHSEASPTHSGHTHSQAGSR--HGQSGSSGH 2216
Query: 1499 GRQGSYHEQSVDRSGHSGYHHSHTTPQG-RSDASHGQSGPRSASRQTR---NEEQSGDGS 1554
GRQG+ H Q+ D + H+ Y + +T +G R+ G S+ + + SG
Sbjct: 2217 GRQGTTHGQTGDTTRHAHYGYGQSTQRGSRTTGRRGSGHSESSDSEVHSWGSHTHSGHIQ 2276
Query: 1555 RHSGSRHHEPSTRAGSSRHSQVGQGESAGSKTSRRQGSSVSQDRDSEGH-SEDSERRSES 1613
+GS+ +P GS+ H ++ T+R S Q + S S +S S
Sbjct: 2277 GQAGSQQRQP----GSTVHGRLETTHGQTGDTTRHGHSGYGQSTQTGSRSSRASHFQSHS 2332
Query: 1614 ASRNHYGSAREQSRHGSRNPRSHQEDRASHGHSAESSRQSGTRHAETSSGGQA 1666
+ R +GS+ + +HGS P + +G S S + H S+ A
Sbjct: 2333 SERQRHGSS-QVWKHGSYGPAEYDYGHTGYGPSGGSRKSISNSHLSWSTDSTA 2384
Score = 470 bits (1210), Expect = e-131
Identities = 556/1962 (28%), Positives = 769/1962 (39%), Gaps = 294/1962 (14%)
Query: 2177 SDASRGQSGSRSASRKTYDKEQSGDGSRHSGSHHHEASSWADSSRHSLVGQGQSSGP--- 2233
S + + + G R ++ +E D H + H SSW++ H G S G
Sbjct: 97 SGSKKHRRGHRHQEEESETEEDEEDTPGHKSGYRH--SSWSEGEEHGY-SSGHSRGTVKC 153
Query: 2234 -RTSRPRGSSVSQDSDSEGHSEDSERR--------SGSASRNHHGSAQEQSRDGSRHPRS 2284
S R + S G+ E S++R S S ++ HGS+ + R+ R +S
Sbjct: 154 RHGSNSRRLGRQGNLSSSGNQEGSQKRYHRSSCGHSWSGGKDRHGSSSVELRE--RINKS 211
Query: 2285 HHEDRAGHGHSAESSRQSGTHHAENSSG---GQAASSHEQARSSAGERH---GSHHQQSA 2338
H G ES S + + G G S HE + + R GS S
Sbjct: 212 HISPSRESGEEYESGSGSNSWERKGHGGLSCGLETSGHESNSTQSRIREQKLGSSCSGSG 271
Query: 2339 DSSRHS---------GIGHGQASSAVRDSGHRGSSGSQAS-----------DSEGHSEDS 2378
DS R S G G Q +S+ S G G+Q S +GH S
Sbjct: 272 DSGRRSHACGYSNSSGCGRPQNASSSCQSHRFGGQGNQFSYIQSGCQSGIKGGQGHGCVS 331
Query: 2379 DTQSVSAHGQAGPHQQSHQESTRGRSAGRSGRSGSFLYQVSTHEQSESAHGRTGTSTGGR 2438
Q S GQ + S S RG A +G+ + Q T S G+ G+ GG
Sbjct: 332 GGQP-SGCGQPESNPCSQSYSQRGYGARENGQPQNCGGQWRTGSSQSSCCGQYGS--GGS 388
Query: 2439 QGSHHKQ------ARDSSRHSTSQEGQDTIHGHPGSSS--------GGRQGSHYEQLVDR 2484
Q + Q R S+ S+++ + +G S S G Q S +EQ V
Sbjct: 389 QSCSNGQHEYGSCGRFSNSSSSNEFSKCDQYGSGSSQSTSFEQHGTGLSQSSGFEQHVCG 448
Query: 2485 SGHSGSHHSHTTSQGRSDASHGHSGSRSASRQTRNDEQSGDGSRHSGSRHHEASSRADSS 2544
SG + H T+SQ HG S+S +T Q G GS S S SS
Sbjct: 449 SGQTCGQHESTSSQSLGYDQHG-----SSSGKTSGFGQHGSGSGQSSGFGQCGSGSGQSS 503
Query: 2545 GHSQVGQ--GQSEGPRTSRNWGSSFSQDSDSQGHSEDSERWSGSASRNHHGSAQEQLRDG 2602
G Q G GQS G +G S S G + R S +S HGS Q
Sbjct: 504 GFGQHGSVSGQSSG------FGQHGSVSGQSSGFGQHESR-SRQSSYGQHGSGSSQ---S 553
Query: 2603 SRHPRSHQEDRAGHGHSADSSRQSGTRHTQTSSGGQAASSHEQARSSAGERHG--SHHQQ 2660
S + + + +G G S QS T Q SG +S Q S +G+ G H +
Sbjct: 554 SGYGQYGSRETSGFGQHGLGSGQS-TGFGQYGSGSGQSSGFGQHGSGSGQSSGFGQHESR 612
Query: 2661 SADSSRHSGIGHGQASSAVRDSGHRGYSGSQASDNEGHSEDSDTQSVSAHGQAGSHQQSH 2720
S SS +GQ SS S G GS+ + G +QS + GQ GS S
Sbjct: 613 SGQSS------YGQHSSGSSQSSGYGQHGSRQTSGFGQHGSGSSQS-TGFGQYGSG--SG 663
Query: 2721 QESARGRSGETSGHSGSFLYQVSTHEQSESSHGWTGPSTRGRQGSRHEQAQDSSRHSASQ 2780
Q S G+ SG S F HE S S H S+ G+ G Q+ +H
Sbjct: 664 QSSGFGQHVSGSGQSSGF----GQHE-SRSGH-----SSYGQHGFGSSQSSGYGQH---- 709
Query: 2781 DGQDTIRGHPGSSRGGRQGYHHEHSVDSSGHSGSHHSHTTSQGRSDASRGQSGSRSASRT 2840
GSS G G+ +H + SSG S S H + G+S GQ GS S +
Sbjct: 710 ----------GSSSGQTSGFG-QHEL-SSGQSSSFGQHGSGSGQSSGF-GQHGSGSGQSS 756
Query: 2841 TRNEEQSGDGSRHSGSRHHEASTHADISRHSQAVQGQSEGSRRSRRQGSSVSQDSDSEGH 2900
+ +S G G +S + +H GSR++ G S S S G
Sbjct: 757 GFGQHESRSGQSSYGQHSSGSSQSSGYGQH---------GSRQTSGFGQHGSGSSQSTGF 807
Query: 2901 SEDSERWSGSASRNHHGSAQEQLRDGSRHP-RSHQEDRAGHGHSADSSR---QSGTRHTQ 2956
+ SA HGS Q +H RSHQ HG + S Q G+ Q
Sbjct: 808 GQYGSGSGQSAGFGQHGSGSGQSSGFGQHESRSHQSSYGQHGSGSSQSSGYGQHGSSSGQ 867
Query: 2957 TSSGGQAASSHEQARSSAGERHGSHHQQSADSSRHSGIGHGQASSAVRDSGHRGYSGSQA 3016
TS GQ SS Q S +HGS QS+ +H G G GQ S + R + S
Sbjct: 868 TSGFGQHRSSSGQY--SGFGQHGSGSGQSSGFGQH-GTGSGQYSGFGQHES-RSHQSSYG 923
Query: 3017 SDNEGHSEDSDT-QSVSAHGQA---GSHQQ-SHQESARGRSGETSGHSGSFLYQVSTHEQ 3071
G S+ S Q S+ GQ G H+ S Q S G+ G SG S F HE
Sbjct: 924 QHGSGSSQSSGYGQHGSSSGQTFGFGQHRSGSGQSSGFGQHGSGSGQSSGF----GQHES 979
Query: 3072 -SESSHGW------TGPSTRGRQGSRHEQAQDSSRHSASQYGQDTIRGHPGSSRGGRQGY 3124
S S G+ + S G+ GS Q+ +H +S GQ T G SS G G+
Sbjct: 980 GSGKSSGFGQHESRSSQSNYGQHGSGSSQSSGYGQHGSSS-GQTTGFGQHRSSSGQYSGF 1038
Query: 3125 HHEHSVDSSGHSGSHHSHTTSQGRSDASRGQSGSRSASRTTRNEEQSGDSSRHSVSRHHE 3184
S S S H T G+S GQ SRS +++ + SG S +H
Sbjct: 1039 GQHGS--GSDQSSGFGQHGTGSGQSSGF-GQYESRSR-QSSYGQHGSGSSQSSGYGQHGS 1094
Query: 3185 ASTHADISRHSQAVQGQSEGSRRSRRQGSSVSQDSDSEGHSEDSERWSGSASRNHRGSVQ 3244
S + GQS G + GS Q S H + + SG A +R
Sbjct: 1095 NSGQTSGFGQHRPGSGQSSGFGQ---YGSGSGQSSGFGQHGSGTGKSSGFAQHEYRSGQS 1151
Query: 3245 EQSRHGSRHPRS----HHEDRAGHG------------------HSADRSRQSGTRHAETS 3282
+HG+ +S HE +G H +D + +G +
Sbjct: 1152 SYGQHGTGSSQSSGCGQHESGSGPTTSFGQHVSGSDNFSSSGQHISDSGQSTGFGQYGSG 1211
Query: 3283 SG-----GQAASSHEQARSSPGERHGSRHQQSADSSRHSGIPRGQAS-SAVRDSRHWGSS 3336
SG GQ S ++ S+ R + H Q+ +++RHS +GQ++ + R +R SS
Sbjct: 1212 SGQSTGLGQGESQQVESGSTVHGRQETTHGQTINTTRHSQSGQGQSTQTGSRVTRRRRSS 1271
Query: 3337 GSQASDSEGHSEESDTQSVSGHGQAGPHQQSHQESARDRSGGRSGRSGSFLYQVSTHEQS 3396
S+ SDSE HS+ S S H QAG H +SGS
Sbjct: 1272 QSENSDSEVHSKVSHRHSEHIHTQAGSHYP---------------KSGS----------- 1305
Query: 3397 ESAHGRTRTSTGRRQGSHHEQARDSSRHSASQEGQDTIRGHPGSSRRGRQGSHYEQSVDR 3456
+ RRQG+ H Q D++RH S GQ T GS GRQ + + D
Sbjct: 1306 ---------TVRRRQGTTHGQRGDTTRHGHSGHGQST---QTGSRTSGRQRFSHSDATDS 1353
Query: 3457 SGHSG-SHHSHTTSQGRSDA--SRGQSGSRSASRQTRNDEQSGDGSRHSWSHHHEASTQA 3513
HSG SH H+ Q S A G+S S R Q+G+ + H S H + STQ
Sbjct: 1354 EVHSGVSHRPHSQEQTHSQAGSQHGESESTVHERHETTYGQTGEATGHGHSGHGQ-STQR 1412
Query: 3514 DSSRHSQSGQGQSAGPRTSRNQGSSVSQDSDSQGHSEDSERW--SGSASRNHRGSAQEQS 3571
S + G G S + + G S S Q H + + SGS G+ Q+
Sbjct: 1413 GSRTTGRRGSGHSESSDSEVHSGGSHRPQSQEQTHGQAGSQHGESGSTVHGRHGTTHGQT 1472
Query: 3572 RDGSRHPTSHH----------EDRAGHGHSAESSRQ---SGTHHAENSSGGQAASSHEQA 3618
D +RH HH R G GHS S + G+H + GQ+ S H ++
Sbjct: 1473 GDTTRHAHYHHGKSTQRGSSTTGRRGSGHSESSDSEVHSGGSHTHSGHTHGQSGSQHGES 1532
Query: 3619 RSSAGERHGSHHQQSADSSRHSGIGHGQAS-SAVRDSGHRGSSGSQASDSEGHSEDSDTQ 3677
S +RH H Q+ D++RHS GH Q + + R +G + +S S+++DSE HS
Sbjct: 1533 ESIIHDRHRITHGQTGDTTRHSYSGHEQTTQTGSRTTGRQRTSHSESTDSEVHS------ 1586
Query: 3678 SVSAHGQAGPHQQSHQESTRGRSAGRSGRSGSFLYQVSTHEQSESAHGRAGPSTGGRQGS 3737
G H+ +E T G+ AG F + HE+ + HG+ G +TG
Sbjct: 1587 -------GGSHRPHSREHTYGQ-AGSQHEEPEF----TVHERHGTTHGQIGDTTG----- 1629
Query: 3738 RHEQARDSSRHSASQEGQDTIRGHPGSRRGGRQGSYHEQSVDRSGHSGSHHSHT-TSQGR 3796
HS S GQ T R GSR GRQ S H +S D HSG H+HT + G+
Sbjct: 1630 ----------HSHSGHGQSTQR---GSRTTGRQRSSHSESSDSEVHSGVSHTHTGHTHGQ 1676
Query: 3797 SDASHGQSGSRSASRETRNEEQSGDGSRHSGSRHHEASTQADSSRHSQSGQGESAGSRRS 3856
+ + HGQS S R Q+GD +RH+ HH +TQ S + G G S S
Sbjct: 1677 AGSQHGQSESIVPERHGTTHGQTGDTTRHA-HYHHGLTTQTGSRTTGRRGSGHSEYSDSE 1735
Query: 3857 RRQGSSVSQDSDSEAYPEDSERRSESASRNHHGSSREQSRDGSRHPGSSHRDTASHVQSS 3916
G S + + SES HG+ Q+ D +RH S H QS+
Sbjct: 1736 GYSGVSHTHSGHTHGQARSQHGESESIVHERHGTIHGQTGDTTRHAHSGHG------QST 1789
Query: 3917 PVQSDSSTAKEHGHFSSLSQDSAYHSGIQSRGSPHSSSSYHYQSEGTERQKGQSGLVWRH 3976
S ++ + GH S DS HSG R PHS H Q+ G++ + +S + RH
Sbjct: 1790 QTGSRTTGRRSSGH--SEYSDSEGHSGFSQR--PHSRGHTHGQA-GSQHGESESIVDERH 1844
Query: 3977 GSYGSADYDYGESGFRHSQHGSVSYNSNPVVFKERSDICKAS 4018
G+ D SG S HG + + + + RS ++S
Sbjct: 1845 GTTHGQTGD--TSGHSQSGHGQSTQSGSSTTGRRRSGHSESS 1884
Score = 338 bits (867), Expect = 6e-92
Identities = 418/1578 (26%), Positives = 583/1578 (36%), Gaps = 165/1578 (10%)
Query: 2497 SQGRSDASHGHSGSRSASRQTRNDEQSGDGSRHSGSRHH---EASSRADSSGHSQVGQGQ 2553
+ G GH S +T DE+ G + SG RH E SSGHS+
Sbjct: 96 ASGSKKHRRGHRHQEEES-ETEEDEEDTPGHK-SGYRHSSWSEGEEHGYSSGHSRGTVKC 153
Query: 2554 SEGPRTSR-----NWGSSFSQDSDSQGHSEDSERWSGSASRNHHGSAQEQLRDGSRHPRS 2608
G + R N SS +Q+ + + S S S ++ HGS+ +LR+ R +S
Sbjct: 154 RHGSNSRRLGRQGNLSSSGNQEGSQKRYHRSSCGHSWSGGKDRHGSSSVELRE--RINKS 211
Query: 2609 HQEDRAGHGHSADSSRQSGTRHTQTSSGGQAASSHEQARSSAGERHGSHHQQSADSSRHS 2668
H SR+SG + ++ SG + S G S H+ ++ SR
Sbjct: 212 H----------ISPSRESGEEY-ESGSGSNSWERKGHGGLSCG-LETSGHESNSTQSRIR 259
Query: 2669 GIGHGQASSAVRDSGHR----GYSGSQASDNEGHSEDS-DTQSVSAHGQAGSHQQSH-QE 2722
G + S DSG R GYS S ++ S + G S+ QS Q
Sbjct: 260 EQKLGSSCSGSGDSGRRSHACGYSNSSGCGRPQNASSSCQSHRFGGQGNQFSYIQSGCQS 319
Query: 2723 SARGRSGETSGHSGSFLYQVSTHEQSESSHGWTGPSTRGRQGSRHEQAQDSSRHSASQDG 2782
+G G G Q S Q ES+ S RG + Q Q+ +
Sbjct: 320 GIKGGQGHGCVSGG----QPSGCGQPESNPCSQSYSQRGYGARENGQPQNCGGQWRTGSS 375
Query: 2783 QDTIRGHPGSSRGGRQGYHHEHSVDSSGHSGSHHSHTTSQGRSDASRGQSGSRSASRTTR 2842
Q + G GS G + + +H S G + S G S S S +
Sbjct: 376 QSSCCGQYGSG-GSQSCSNGQHEYGSCGRFSNSSSSNEFSKCDQYGSGSSQSTSFEQHGT 434
Query: 2843 NEEQSGDGSRHSGSRHHEASTHADISRHSQAVQGQSEGSRRSRRQGSSVSQDSDSEGHSE 2902
QS +H H S S S ++ G S S G +
Sbjct: 435 GLSQSSGFEQHVCGSGQTCGQHESTSSQSLGYDQHGSSSGKTSGFGQHGSGSGQSSGFGQ 494
Query: 2903 DSERWSGSASRNHHGSAQEQLRDGSRHPRSHQEDRAGHGHSADSSRQSGTRHTQTSSGGQ 2962
S+ HGS Q +H S +G G SRQS + Q SG
Sbjct: 495 CGSGSGQSSGFGQHGSVSGQSSGFGQHG-SVSGQSSGFGQHESRSRQSS--YGQHGSGSS 551
Query: 2963 AASSHEQARSSAGERHGSHHQQSADSSRHSGIGHGQASSAVRDSGHRGYSGSQASDNEGH 3022
+S + Q S G H S S+ G GQ S S G GS + + G
Sbjct: 552 QSSGYGQYGSRETSGFGQHGLGSGQST-----GFGQYGSGSGQSSGFGQHGSGSGQSSGF 606
Query: 3023 SEDSDTQSVSAHGQ--AGSHQQSHQESARGRSGETSGHSGSFLYQVSTHEQSESSHGWTG 3080
+ S++GQ +GS Q S R G GS Q + Q S G +
Sbjct: 607 GQHESRSGQSSYGQHSSGSSQSSGYGQHGSRQTSGFGQHGSGSSQSTGFGQYGSGSGQSS 666
Query: 3081 PSTRGRQGSRHEQA--QDSSRHSASQYGQDTIRGHPGSSRGGRQGYHHEHSVDSSGHSGS 3138
+ GS Q SR S YGQ GSS+ G H SSG +
Sbjct: 667 GFGQHVSGSGQSSGFGQHESRSGHSSYGQHGF----GSSQSSGYGQHGS----SSGQTSG 718
Query: 3139 HHSHTTSQGRSDASRGQSGSRSASRTTRNEEQSGDSSRHSVSRHHEASTHADISRHSQAV 3198
H S G+S +S GQ GS S + + SG +H S + +HS
Sbjct: 719 FGQHELSSGQS-SSFGQHGSGSGQSSGFGQHGSGSGQSSGFGQHESRSGQSSYGQHSSGS 777
Query: 3199 QGQS----EGSRRSRRQGSSVSQDSDSEGHSEDSERWSGSASRNHRGSVQEQSR-HGSRH 3253
S GSR++ G S S S G + SA GS QS G
Sbjct: 778 SQSSGYGQHGSRQTSGFGQHGSGSSQSTGFGQYGSGSGQSAGFGQHGSGSGQSSGFGQHE 837
Query: 3254 PRSHHEDRAGHGHSADRSR---QSGTRHAETSSGGQAASSHEQARSSPGERHGSRHQQSA 3310
RSH HG + +S Q G+ +TS GQ SS Q S +HGS QS+
Sbjct: 838 SRSHQSSYGQHGSGSSQSSGYGQHGSSSGQTSGFGQHRSSSGQY--SGFGQHGSGSGQSS 895
Query: 3311 DSSRHSGIPRGQASSAVRDSRHWGSSGSQASDSEGHSEESDTQSVSGHGQAGPHQQSHQE 3370
+H G GQ S +G S++ S S + SG+GQ G
Sbjct: 896 GFGQH-GTGSGQYSG-------FGQHESRSHQSSYGQHGSGSSQSSGYGQHGSSSGQTFG 947
Query: 3371 SARDRSGGRSGRSGSFLYQVSTHEQSESAHGRTRTSTGRRQGSHHEQARDSSRHSASQEG 3430
+ RSG SG+S F S QS S G+ + +G+ G ++R SS+ + Q G
Sbjct: 948 FGQHRSG--SGQSSGFGQHGSGSGQS-SGFGQHESGSGKSSGFGQHESR-SSQSNYGQHG 1003
Query: 3431 QDTIRGHPGSSRRGRQGSHYEQSVDRSGHSGSHHSHTTSQGRSDASRGQSGSRSASRQTR 3490
GSS Q S Y Q SG + H +S G+ GQ GS S
Sbjct: 1004 S-------GSS----QSSGYGQHGSSSGQTTGFGQHRSSSGQYSGF-GQHGSGSDQSSGF 1051
Query: 3491 NDEQSGDGSRHSWSHHHEASTQADSSRHSQSGQGQSAG---PRTSRNQGSSVSQDSDSQG 3547
+G G + + S Q+ +H SG QS+G ++ Q S Q G
Sbjct: 1052 GQHGTGSGQSSGFGQYESRSRQSSYGQHG-SGSSQSSGYGQHGSNSGQTSGFGQHRPGSG 1110
Query: 3548 HSEDSERWSGSASRNHRGSAQEQSRDGSRHPTSHHEDRAGHG----HSAESSRQSGTHHA 3603
S ++ GS S G Q S G + HE R+G H SS+ SG
Sbjct: 1111 QSSGFGQY-GSGSGQSSGFGQHGSGTGKSSGFAQHEYRSGQSSYGQHGTGSSQSSGCGQH 1169
Query: 3604 ENSSGGQAASSHEQARSSAGERHGSHHQQSADSSRHS--GIGHGQASSAVRDSGHRGSSG 3661
E+ SG + + S G H S S+ G G GQ++ + + SG
Sbjct: 1170 ESGSGPTTSFGQHVSGSDNFSSSGQHISDSGQSTGFGQYGSGSGQSTGLGQGESQQVESG 1229
Query: 3662 SQASDSEGHSEDSDTQSVSA--HGQAGPHQQSHQES--TRGRSAGRSGRSGSFLYQVSTH 3717
S G E + Q+++ H Q+G Q + S TR R + +S S S ++ +H
Sbjct: 1230 STV---HGRQETTHGQTINTTRHSQSGQGQSTQTGSRVTRRRRSSQSENSDSEVHSKVSH 1286
Query: 3718 EQSESAHGRAG---PSTGG----RQGSRHEQARDSSRHSASQEGQDTIRGHPGSRRGGRQ 3770
SE H +AG P +G RQG+ H Q D++RH S GQ T GSR GRQ
Sbjct: 1287 RHSEHIHTQAGSHYPKSGSTVRRRQGTTHGQRGDTTRHGHSGHGQST---QTGSRTSGRQ 1343
Query: 3771 GSYHEQSVDRSGHSG-SHHSHTTSQGRSDAS--HGQSGSRSASRETRNEEQSGDGSRHSG 3827
H + D HSG SH H+ Q S A HG+S S R Q+G+ + H
Sbjct: 1344 RFSHSDATDSEVHSGVSHRPHSQEQTHSQAGSQHGESESTVHERHETTYGQTGEATGHGH 1403
Query: 3828 SRHHEASTQADSSRHSQSGQGESAGSRRSRRQGSSVSQDSDSEAYPEDSERRSESASRNH 3887
S H + STQ S + G G S S G S S + + + + ES S H
Sbjct: 1404 SGHGQ-STQRGSRTTGRRGSGHSESSDSEVHSGGSHRPQSQEQTHGQAGSQHGESGSTVH 1462
Query: 3888 --HGSSREQSRDGSRHPGSSHRDTASHVQSSPVQSDSSTAKEHGHFSSLSQDSAYHSGIQ 3945
HG++ Q+ D +RH H Q SST G S S DS HSG
Sbjct: 1463 GRHGTTHGQTGDTTRHAHYHH--------GKSTQRGSSTTGRRGSGHSESSDSEVHSG-- 1512
Query: 3946 SRGSPHSSSSYHYQSEGTERQKGQSGLVWRHGSYGSADYDYGESGFRHSQHGSVSYNSNP 4005
GS+ + + +G+SG +H + S+ ++ +
Sbjct: 1513 -------------------------------GSHTHSGHTHGQSGSQHGESESIIHDRHR 1541
Query: 4006 VVFKERSDICKASAFGKD 4023
+ + D + S G +
Sbjct: 1542 ITHGQTGDTTRHSYSGHE 1559
Score = 315 bits (806), Expect = 8e-85
Identities = 311/1083 (28%), Positives = 443/1083 (40%), Gaps = 188/1083 (17%)
Query: 83 QAYYESTRKENLPISGHKHRKHSHHDKHEDNKQEENKENRKRPSSLERRNNRKGNKGRS- 141
Q + S ++ SG HR HS H Q ++ + ER G G +
Sbjct: 1343 QRFSHSDATDSEVHSGVSHRPHSQEQTHS---QAGSQHGESESTVHERHETTYGQTGEAT 1399
Query: 142 ------------KSPRETG--GKRHESSSEKKERKGYSPTHREEEYGKNHHNSSKKEKNK 187
+ R TG G H SS+ + G S + +E S E
Sbjct: 1400 GHGHSGHGQSTQRGSRTTGRRGSGHSESSDSEVHSGGSHRPQSQEQTHGQAGSQHGESGS 1459
Query: 188 TENTRLGDNRKRLSE--RLEEKEDNEEGVYDYENTGRMTQKWIQSG----HIATYYTIQD 241
T + R G + + R + TGR +S H +T
Sbjct: 1460 TVHGRHGTTHGQTGDTTRHAHYHHGKSTQRGSSTTGRRGSGHSESSDSEVHSGGSHTHSG 1519
Query: 242 EAYDTTDSLLEENK--IYERSRSSDGKSSSQVNRSR--HENTSQVPLQESRTRKRRGSRV 297
+ + S E++ I++R R + G++ S HE T+Q SRT R+ +
Sbjct: 1520 HTHGQSGSQHGESESIIHDRHRITHGQTGDTTRHSYSGHEQTTQTG---SRTTGRQRTSH 1576
Query: 298 SQDRDSEGHSEDSER-HS-----GSASRNH----------HGSAWEQSRDGSRHP----- 336
S+ DSE HS S R HS G A H HG+ Q D + H
Sbjct: 1577 SESTDSEVHSGGSHRPHSREHTYGQAGSQHEEPEFTVHERHGTTHGQIGDTTGHSHSGHG 1636
Query: 337 -------RSHDEDRASHGHSADSSRQSGTRHAETS-SRGQTASSHEQARSSPGERHGSGH 388
R+ R+SH S+DS SG H T + GQ S H Q+ S ERHG+ H
Sbjct: 1637 QSTQRGSRTTGRQRSSHSESSDSEVHSGVSHTHTGHTHGQAGSQHGQSESIVPERHGTTH 1696
Query: 389 QQSADSSRHSATGRGQASSAVS-DRGHRGSSGSQASDSEGHSENSDTQSVSGHGKAGLRQ 447
Q+ D++RH+ G + S G RGS S+ SDSEG+S S T S HG+A +
Sbjct: 1697 GQTGDTTRHAHYHHGLTTQTGSRTTGRRGSGHSEYSDSEGYSGVSHTHSGHTHGQARSQH 1756
Query: 448 QSHQESTRGRSGERSGRSGSSLYQVSTHEQPDSAHGR---TGTSTGGRQGSHHEQARDSS 504
+ R G G++G T S HG+ TG+ T GR+ S H + DS
Sbjct: 1757 GESESIVHERHGTIHGQTGD------TTRHAHSGHGQSTQTGSRTTGRRSSGHSEYSDSE 1810
Query: 505 RHSASQEGQDTIRGHPGSSRGG-----------RQGSHHEQSVNRSGHSGSHHSHTTSQG 553
HS + + RGH G R G+ H Q+ + SGHS S H +T G
Sbjct: 1811 GHSGFSQRPHS-RGHTHGQAGSQHGESESIVDERHGTTHGQTGDTSGHSQSGHGQSTQSG 1869
Query: 554 RSDASHGQSGSRSASRQTRNEEQSGDGTRHSGSRHHEASSQ------------------- 594
S +SG S + +E SG HSG H +A SQ
Sbjct: 1870 SSTTGRRRSGH---SESSDSEVHSGGSHTHSGHTHSQARSQHGESESTVHKRHQTTHGQT 1926
Query: 595 ADSSRHSQVGQGQS--SGPRTSRNQGSSVSQDSDSQG------------HSEDSERW--S 638
D++ H GQ+ +G RT+ +GS S+ SDS+G H + + S
Sbjct: 1927 GDTTEHGHPSHGQTIQTGSRTTGRRGSGHSEYSDSEGPSGVSHTHSGHTHGQAGSHYPES 1986
Query: 639 GSASRNHHGSAQEQSRDGSRHPRSHHEDR------------AGHGHSADSSRKSGTRHTQ 686
GS+ HG+ Q+ D +RH S H +GH +DS SG HT
Sbjct: 1987 GSSVHERHGTTHGQTADTTRHGHSGHGQSTQRGSRTTGRRASGHSEYSDSEGHSGVSHTH 2046
Query: 687 NSSS-GQAASSHEQARSSAGERHGSRHQLQSADSSRHSGTGHGQASS-AVRDSGHRGSSG 744
+ + GQA S H ++ SS ERHG+ H Q+ D++RH+ +GHGQ++ R +G RGS
Sbjct: 2047 SGHAHGQAGSQHGESGSSVHERHGTTHG-QTGDTTRHAHSGHGQSTQRGSRTAGRRGSGH 2105
Query: 745 SQATDSEGHSEDSDTQSVSGHGQAGHHQQSHQESARDRSGERSRRSGSFLYQVSTHKQSE 804
S+++DSE HS S T S +GQA + R G ++G T + +
Sbjct: 2106 SESSDSEVHSGVSHTHSGHTYGQARSQHGESGSAIHGRQGTIHGQTGD------TTRHGQ 2159
Query: 805 SSHGW---TGPSTGVRQGSHHEQARDN----------SRHSASQDGQDTIRGHPGSSRRG 851
S HG TG T RQ S H ++ D+ S H+ SQ G G GSS G
Sbjct: 2160 SGHGQSTQTGSRTTGRQRSSHSESSDSEVHSEASPTHSGHTHSQAGSR--HGQSGSSGHG 2217
Query: 852 RQGSHHEQSVDRSGHSGSHHSHTTSQG-RSDASRGQSGSRSA--------SRTTRNEEQS 902
RQG+ H Q+ D + H+ + +T +G R+ RG S S+ S T Q
Sbjct: 2218 RQGTTHGQTGDTTRHAHYGYGQSTQRGSRTTGRRGSGHSESSDSEVHSWGSHTHSGHIQG 2277
Query: 903 RDGS--RHSGSRHHE--ASSH---ADISRHSQAGQGQSEGSRTSRRQGSSVSQDSDSEGH 955
+ GS R GS H ++H D +RH +G GQ S + GS S+ S + H
Sbjct: 2278 QAGSQQRQPGSTVHGRLETTHGQTGDTTRHGHSGYGQ------STQTGSRSSRASHFQSH 2331
Query: 956 SEDSERWSGSASRNHRGSAQEQSRHGSRHPRSHHEDRAGHGHSADSSRQSGTPHAETSSG 1015
S + +R GS+Q +HGS P + G+G S S + H S+
Sbjct: 2332 SSERQR---------HGSSQVW-KHGSYGPAEYDYGHTGYGPSGGSRKSISNSHLSWSTD 2381
Query: 1016 GQA 1018
A
Sbjct: 2382 STA 2384
Score = 127 bits (320), Expect = 2e-28
Identities = 135/515 (26%), Positives = 207/515 (40%), Gaps = 65/515 (12%)
Query: 97 SGHKHRK-HSHHDKHEDNKQEENKENRKRPSSLERRNNRKGNKGRSKSPRETG--GKRHE 153
SGH H + S H + E + ++ + + + R TG G H
Sbjct: 1897 SGHTHSQARSQHGESESTVHKRHQTTHGQTGDTTEHGHPSHGQTIQTGSRTTGRRGSGHS 1956
Query: 154 SSSEKKERKGYSPTHREEEYGK--NHHNSSKKEKNKTENTRLGDNRKRLSERLEEKEDNE 211
S+ + G S TH +G+ +H+ S ++ T G + R +
Sbjct: 1957 EYSDSEGPSGVSHTHSGHTHGQAGSHYPESGSSVHERHGTTHGQTAD--TTRHGHSGHGQ 2014
Query: 212 EGVYDYENTGRMTQKWIQ----SGHIATYYTIQDEAYDTTDSLLEEN--KIYERSRSSDG 265
TGR + GH +T A+ S E+ ++ER ++ G
Sbjct: 2015 STQRGSRTTGRRASGHSEYSDSEGHSGVSHTHSGHAHGQAGSQHGESGSSVHERHGTTHG 2074
Query: 266 KSSSQVNRSRHENTSQVPLQESRTRKRRGSRVSQDRDSEGHSEDSERHSGSA---SRNHH 322
++ R H Q + SRT RRGS S+ DSE HS S HSG +R+ H
Sbjct: 2075 QTGD-TTRHAHSGHGQSTQRGSRTAGRRGSGHSESSDSEVHSGVSHTHSGHTYGQARSQH 2133
Query: 323 GSAWE-----------QSRDGSRH------------PRSHDEDRASHGHSADS---SRQS 356
G + Q+ D +RH R+ R+SH S+DS S S
Sbjct: 2134 GESGSAIHGRQGTIHGQTGDTTRHGQSGHGQSTQTGSRTTGRQRSSHSESSDSEVHSEAS 2193
Query: 357 GTRHAETSSRGQTASSHEQARSSPGERHGSGHQQSADSSRHSATGRGQASSAVS-DRGHR 415
T T S Q S H Q+ SS R G+ H Q+ D++RH+ G GQ++ S G R
Sbjct: 2194 PTHSGHTHS--QAGSRHGQSGSSGHGRQGTTHGQTGDTTRHAHYGYGQSTQRGSRTTGRR 2251
Query: 416 GSSGSQASDSEGHSENSDTQSVSGHGKAGLRQQSHQESTRGRSGERSGRSGSSLYQVSTH 475
GS S++SDSE HS S T S G+AG +Q+ + GR G++G +
Sbjct: 2252 GSGHSESSDSEVHSWGSHTHSGHIQGQAGSQQRQPGSTVHGRLETTHGQTGDT------- 2304
Query: 476 EQPDSAHGRTGTSTGGRQGSHHEQARDSSRHSASQEGQDTIRGHPGSSRGGRQGSHHEQS 535
+ HG +G + GS +A HS+ R GSS+ + GS+
Sbjct: 2305 ----TRHGHSGYGQSTQTGSRSSRASHFQSHSSE-------RQRHGSSQVWKHGSYGPAE 2353
Query: 536 VNRSGHSGSHHSHTTSQGRSDASHGQSGSRSASRQ 570
+ GH+G S + + S++ S +A++Q
Sbjct: 2354 YD-YGHTGYGPSGGSRKSISNSHLSWSTDSTANKQ 2387
>gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens]
Length = 1301
Score = 263 bits (673), Expect = 2e-69
Identities = 309/1364 (22%), Positives = 509/1364 (37%), Gaps = 122/1364 (8%)
Query: 1718 QASDSEGHSEESDTQSVSAHGQAGPHQQSHQESTRGQSGERSGRSGSFLYQVSTHEQSES 1777
Q+ E H E+S + A + + T +SG +++ Q +
Sbjct: 20 QSKPLERHVEKSMNLHLLARSNVSVQDELNASGTIKESGV-------LVHEGDRGRQENT 72
Query: 1778 AHGRTGPSTGGRQRSRHEQARDSSRHSASQEGQ-DTIRGHPGSSRG-GRQGSH-YEQSVD 1834
G G G + ++ + A++EG + G G + G G H E+++
Sbjct: 73 QDGHKGEGNGSKWAEVGGKSFSTYSTLANEEGNIEGWNGDTGKAETYGHDGIHGKEENIT 132
Query: 1835 SSGHSG----------SHHSHTTSQERSDVSRGQSGSRSVSRQTRNEKQSGDGSRHSGSR 1884
++G G ++ S+T + G G + ++ G S +
Sbjct: 133 ANGIQGQVSIIDNAGATNRSNTNGNTDKNTQNGDVGDAGHNEDVAVVQEDGPQVAGSNNS 192
Query: 1885 HHEASSRADSSRHSQVGQGQSSGPRTSRNQGSSVSQDSDSQGHSEDSERWSGSASRNHLG 1944
++S ++ + + S+ G+ ++ + G + GS S N
Sbjct: 193 TDNEDEIIENSCRNEGNTSEITPQINSKRNGTKEAEVTPGTGEDAGLDNSDGSPSGN--- 249
Query: 1945 SAWEQSRDGSRHPGSHHEDRAGHGH--SADSSRQSGTRHTES----SSRGQAASSHEQAR 1998
A E +GS G ++ AG+G S +S Q G H + SS GQ + S E
Sbjct: 250 GADEDEDEGS---GDDEDEEAGNGKDSSNNSKGQEGQDHGKEDDHDSSIGQNSDSKEYYD 306
Query: 1999 SSAGERHGSHHQLQSADSSRH----SGIGHGQASSAVRDSGHRGYSGSQ------ASDSE 2048
E H+++ +S+ +GI S + D+ + S+ +SE
Sbjct: 307 PEGKE--DPHNEVDGDKTSKSEENSAGIPEDNGSQRIEDTQKLNHRESKRVENRITKESE 364
Query: 2049 GHSED-SDTQSVSAQGKAGPHQQSHKESARGQSG-ESSGRSGSFLYQVSTHEQSE--STH 2104
H+ S + + +G + ++ KE +G G E G+ G L + + Q E +
Sbjct: 365 THAVGKSQDKGIEIKGPSSGNRNITKEVGKGNEGKEDKGQHGMILGKGNVKTQGEVVNIE 424
Query: 2105 GQSAPSTGGRQGSHYDQAQDSSRHSASQEGQDTIRGHPGPSRGGRQGSHQEQSVDRSGHS 2164
G S G + H + DS+ +G D+ ++S+ +
Sbjct: 425 GPGQKSEPGNKVGHSNTGSDSN-----SDGYDSY-------------DFDDKSMQGDDPN 466
Query: 2165 GSHHSHTTSQGRSDASRGQSGSRSASRKTYDKEQSGDGSRHSGSHHHEASSWADSSRHSL 2224
S S+ S++ S AS + + + +G+GS G+ ++ S +D++
Sbjct: 467 SSDESNGNDDANSESDNNSSSRGDASYNSDESKDNGNGSDSKGAEDDDSDSTSDTNNSDS 526
Query: 2225 VGQGQSSGP---RTSRPRGSSVSQDSDSE--GHSEDSERRSGSASRNHHGSAQEQSRDGS 2279
G G + ++ +G S S DSDS +S DS S S S + + S+ S D S
Sbjct: 527 NGNGNNGNDDNDKSDSGKGKSDSSDSDSSDSSNSSDSSDSSDSDSSDSNSSSDSDSSD-S 585
Query: 2280 RHPRSHHEDRAGHGHSAESSRQSGTHHAENSSGGQAASSHEQARSSAGERHGSHHQQSAD 2339
S D + +S++SS S + + +SS SS ++ SS E S +D
Sbjct: 586 DSSDSSDSDSSDSSNSSDSSDSSDSSDSSDSSD----SSDSKSDSSKSESDSSDSDSKSD 641
Query: 2340 SSRHSGIGHGQASSAVRDSGHRGSSGSQASDSEGHSEDSDTQSVSAHGQAGPHQQSHQES 2399
SS + + S+ S+ S +SDS S+ SD+ S S + S S
Sbjct: 642 SSDSNS-----SDSSDNSDSSDSSNSSNSSDSSDSSDSSDSSSSSDSSNSSDSSDSSDSS 696
Query: 2400 TRGRSAGRSGRSGSFLYQVSTHEQSESAHGRTGTSTGGRQGSHHKQARDSSRHSTSQEGQ 2459
S+ S S S S S S+ + S+ S+ + DSS S S +
Sbjct: 697 NSSESSDSSDSSDSDSSDSSDSSNSNSSDSDSSNSSDSSDSSNSSDSSDSSDSSNSSDSS 756
Query: 2460 DTIHGHPGSSSGGRQGSHYEQLVDRSGHSGSHHSHTTSQGRSDASHGHSGSRSASRQTRN 2519
D+ +SS S D S S S+ S +S SD+S+ S S+ +
Sbjct: 757 DS--SDSSNSSDSSDSSDSSDSSDSSNSSDSNDSSNSSDS-SDSSNSSDSSNSSDSSDSS 813
Query: 2520 DEQSGDGSRHSGSRHHEASSRADSSGHSQVGQGQSEGPRTSRNWGSSFSQDSDSQGHSED 2579
D D S S S + SS + +S S S+G + + S S SDS S+
Sbjct: 814 DSSDSDSSNSSDSSNSSDSSDSSNSSDSSDSSDSSDGSDSDSSNRSDSSNSSDSSDSSDS 873
Query: 2580 SERWSGSASRNHHGSAQEQLRDGSRHPRSHQEDRAGHGHSADSSRQSGTRHTQTSSGGQA 2639
S S S + + S+ D S S D S+DSS S + + SS
Sbjct: 874 SNSSDSSDSSDSNESSNSS--DSSDSSNSSDSD------SSDSSNSSDSSDSSNSSDSSE 925
Query: 2640 ASSHEQARSSAGERHGSHHQQSADSSRHSGIGHGQASSAVRDSGHRGYSGSQASDNEGHS 2699
+S+ +S+ + S S+DSS S + SS DS S S S N S
Sbjct: 926 SSNSSDNSNSSDSSNSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSNSSDSSDSSNSSDS 985
Query: 2700 EDSDTQSVSAHGQAGSHQQSHQESARGRSGETSGHSGSFLYQVSTHEQSESSHGWTGPST 2759
DS S S+ S+ +S+ S S + ++ + S+SS S+
Sbjct: 986 SDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSS-----DSS 1040
Query: 2760 RGRQGSRHEQAQDSSRHSASQDGQDTIRGHPGSSRGGRQGYHHEHSVDSSGHSGSHHSHT 2819
S + DSS S S D D+ S DSS S S S
Sbjct: 1041 DSSDSSDSSDSSDSSNSSDSSDSSDS-----------------SDSSDSSDSSDSSDSSE 1083
Query: 2820 TSQGRSDASRGQSGSRSASRTTRNEEQSGDGSRHSGSRHHEASTHADISRHSQAVQGQSE 2879
+S ++ S S S + + S D S S S + S+ + S S S+
Sbjct: 1084 SSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSD 1143
Query: 2880 GSRRSRRQGSSVSQDSDSEGHSEDSERWSGSASRNHHGSAQEQLRDGSRHPRSHQEDRAG 2939
S S SS S DS S DS S S+ ++ + + S D +
Sbjct: 1144 SSDSSESSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSD 1203
Query: 2940 HGHSADSSRQSGTRHTQTSSGGQAASSHEQARSSAGERHGSHHQQSADSSRHSGIGHGQA 2999
S+DSS S + + SS +S ++ S+ S S+DSS S +
Sbjct: 1204 SSDSSDSSDSSDSSDSSDSSDSSDSSDSNESSDSSDSSDSSDSSNSSDSSDSS-----DS 1258
Query: 3000 SSAVRDSGHRGYSGSQASDNEGHSEDSDTQSVSAHGQAGSHQQS 3043
S + DS S S++ + + DSD+ S G +H S
Sbjct: 1259 SDSTSDSNDESDSQSKSGNGNNNGSDSDSDS---EGSDSNHSTS 1299
Score = 263 bits (673), Expect = 2e-69
Identities = 313/1376 (22%), Positives = 501/1376 (36%), Gaps = 154/1376 (11%)
Query: 1358 GSRHQQSADSSRHSGIGHRQASSAVRDSGHRGSSGSQVTNSEGHSE--DSDTQSVSAHGQ 1415
G R +Q H G G+ + V G S+ S + N EG+ E + DT +G
Sbjct: 64 GDRGRQENTQDGHKGEGNGSKWAEV--GGKSFSTYSTLANEEGNIEGWNGDTGKAETYGH 121
Query: 1416 AGPHQQSHKESARGQSGESSGRSRSFLYQVSSHEQSESTHGQTAPSTGGRQGSRHEQARN 1475
G H + +A G G+ S + + +T+G T +T + G + N
Sbjct: 122 DGIHGKEENITANGIQGQVS------IIDNAGATNRSNTNGNTDKNT--QNGDVGDAGHN 173
Query: 1476 SSRHSASQDGQDTIRGHPGSSRGGRQGSYHEQSVDRSGHSGYHHSHTTPQGRSDASHGQS 1535
+DG P + ++ ++ S + + S TPQ
Sbjct: 174 EDVAVVQEDG-------PQVAGSNNSTDNEDEIIENSCRNEGNTSEITPQ---------- 216
Query: 1536 GPRSASRQTRNEEQSGDGSRHSGSRHHEPSTRAGSSRHSQVGQGESAGSKTSRRQGSSVS 1595
S+ +G++ E + G GE AG S S
Sbjct: 217 ----------------INSKRNGTKEAEVTP----------GTGEDAGLDNSDGSPSGNG 250
Query: 1596 QDRDSE---GHSEDSERRSESASRNHYGSAREQSRHGSRNPRSHQEDRASHGHSAESSRQ 1652
D D + G ED E + S N+ +E HG + H + S E
Sbjct: 251 ADEDEDEGSGDDEDEEAGNGKDSSNN-SKGQEGQDHGKED--DHDSSIGQNSDSKEYYDP 307
Query: 1653 SGTRHAETSSGGQAASSQEQARSSPGERHGSRHQQSADSSTDSGTGRRQDSSVVGDSGNR 1712
G G S E+ SA D+G+ R +D+ + ++
Sbjct: 308 EGKEDPHNEVDGDKTSKSEE--------------NSAGIPEDNGSQRIEDTQKLNHRESK 353
Query: 1713 GSSGSQASDSEGHSE-ESDTQSVSAHGQAGPHQQSHQESTRGQSG-ERSGRSGSFLYQVS 1770
+SE H+ +S + + G + ++ +E +G G E G+ G L + +
Sbjct: 354 RVENRITKESETHAVGKSQDKGIEIKGPSSGNRNITKEVGKGNEGKEDKGQHGMILGKGN 413
Query: 1771 THEQSESAHGRTGPSTGGRQRSRHEQARDSSRHSASQEGQDTIRGHPGSSRGGRQGSHYE 1830
Q E + GP G + ++ ++ ++ +G D+ S +G S E
Sbjct: 414 VKTQGEVVNIE-GP--GQKSEPGNKVGHSNTGSDSNSDGYDSYDFDDKSMQGDDPNSSDE 470
Query: 1831 QSVDSSGHSGSHHSHTTSQERSDVSRGQSGSRSVSRQTRNEKQSGDGSRHSGSRHHEASS 1890
+ + +S S ++ S R D S S K +G+GS G+ ++ S
Sbjct: 471 SNGNDDANSESDNN---SSSRGDASYNSDES----------KDNGNGSDSKGAEDDDSDS 517
Query: 1891 RADSSRHSQVGQGQS---SGPRTSRNQGSSVSQDSDSQGHSEDSERW----SGSASRNHL 1943
+D++ G G + ++ +G S S DSDS S S+ S S+ N
Sbjct: 518 TSDTNNSDSNGNGNNGNDDNDKSDSGKGKSDSSDSDSSDSSNSSDSSDSSDSDSSDSNSS 577
Query: 1944 GSAWEQSRDGSRHPGSHHEDRAGHGHSADSSRQSGTRHTESSSRGQAASSHEQARSSAGE 2003
+ D S S D + S+DSS S + + SS ++ SS ++ SS +
Sbjct: 578 SDSDSSDSDSSDSSDSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSKSDSSKSESDSSDSD 637
Query: 2004 RHGSHHQLQSADSSRHSGIGHGQASSAVRDSGHRGYSGSQASDSEGHSEDSDTQSVSAQG 2063
S+DSS +S DS S S +SDS S+ SD+ S S
Sbjct: 638 SKSDSSDSNSSDSSDNS------------DSSDSSNS-SNSSDSSDSSDSSDSSSSSDSS 684
Query: 2064 KAGPHQQSHKESARGQSGESSGRSGSFLYQVSTHEQSESTHGQSAPSTGGRQGSHYDQAQ 2123
+ S S +S +SS S S S S S+ S+ S+ S+ +
Sbjct: 685 NSSDSSDSSDSSNSSESSDSSDSSDSDSSDSSDSSNSNSSDSDSSNSSDSSDSSNSSDSS 744
Query: 2124 DSSRHSASQEGQDTIRGHPGPSRGGRQGSHQEQSVDRSGHSGSHHSHTTSQGRSDASRGQ 2183
DSS S S + D+ S S D S S S S +S
Sbjct: 745 DSSDSSNSSDSSDS--------------SDSSNSSDSSDSSDSSDSSDSSNSSDSNDSSN 790
Query: 2184 SGSRSASRKTYDKEQSGDGSRHSGSHHHEASSWADSSRHSLVGQGQSSGPRTSRPRGSSV 2243
S S S + D S D S S S ++S+ +DSS S +S SS
Sbjct: 791 SSDSSDSSNSSDSSNSSDSSDSSDSSDSDSSNSSDSS-------NSSDSSDSSNSSDSSD 843
Query: 2244 SQDSDSEGHSEDSERRSGSASRNHHGSAQEQSRDGSRHPRSHHEDRAGHGHSAESSRQSG 2303
S DS S+G DS RS S++ + + + S S + + S++SS S
Sbjct: 844 SSDS-SDGSDSDSSNRSDSSNSSDSSDSSDSSNSSDSSDSSDSNESSNSSDSSDSSNSSD 902
Query: 2304 THHAENSSGGQAASSHEQARSSAGERHGSHHQQSADSSRHSGIGHGQASSAVRDSGHRGS 2363
+ +++S+ ++ S + SS + S + S+DSS S SS DS +
Sbjct: 903 SDSSDSSNSSDSSDSSNSSDSSESS-NSSDNSNSSDSSNSSDSSDSSDSSNSSDSSNSSD 961
Query: 2364 SGSQASDSEGHSEDSDTQSVSAHGQAGPHQQSHQESTRGRSAGRSGRSGSFLYQVSTHEQ 2423
S + + S+ +S DS S S+ S S S+ S S S S+
Sbjct: 962 SSNSSDSSDSNSSDSSDSSNSSDS-----SDSSDSSDSSDSSDSSNSSDSSDSSDSSDSS 1016
Query: 2424 SESAHGRTGTSTGGRQGSHHKQARDSSRHSTSQEGQDTIHGHPGSSSGGRQGSHYEQLVD 2483
+ S + S+ S + DSS S S + D+ + S S S D
Sbjct: 1017 NSSDSSNSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSS-----D 1071
Query: 2484 RSGHSGSHHSHTTSQGRSDASHGHSGSRSASRQTRNDEQSGDGSRHSGSRHHEASSRADS 2543
S S S S +S ++ S S S + + S D S S S + SS +
Sbjct: 1072 SSDSSDSSDSSESSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSD 1131
Query: 2544 SGHSQVGQGQSEGPRTSRNWGSSFSQDSDSQGHSEDSERWSGSASRNHHGSAQEQLRDGS 2603
S S S+ +S + SS S DS S DS S S+ ++ + +
Sbjct: 1132 SSDSSDSSNSSDSSDSSESSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSD 1191
Query: 2604 RHPRSHQEDRAGHGHSADSSRQSGTRHTQTSSGGQAASSHEQARSSAGERHGSHHQQSAD 2663
S D + S+DSS S + + SS +S ++ S+ S S+D
Sbjct: 1192 SSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSNESSDSSDSSDSSDSSNSSD 1251
Query: 2664 SSRHSGIGHGQASSAVRDSGHRGYSGSQASDNEGHSEDSDTQSVSAHGQAGSHQQS 2719
SS S +S + DS S S++ + + DSD+ S G +H S
Sbjct: 1252 SSDSS-----DSSDSTSDSNDESDSQSKSGNGNNNGSDSDSDS---EGSDSNHSTS 1299
Score = 262 bits (670), Expect = 4e-69
Identities = 285/1236 (23%), Positives = 463/1236 (37%), Gaps = 105/1236 (8%)
Query: 1189 GHSGSH--HSHTTSQGRSDA-----SHGQSGSRSASRQTRKDKQSGDGSRHSGSRHHEAA 1241
GH G H + T+ G + G + + + T K+ Q+GD
Sbjct: 120 GHDGIHGKEENITANGIQGQVSIIDNAGATNRSNTNGNTDKNTQNGDVG----------- 168
Query: 1242 SWADSSRHSQVGQEQSSGSRTSRHQGSSVSQDS---DSERHSDDSERLSGSASRNHHGSS 1298
D+ + V Q G + + S+ ++D +S R+ ++ ++ + +G+
Sbjct: 169 ---DAGHNEDVAVVQEDGPQVAGSNNSTDNEDEIIENSCRNEGNTSEITPQINSKRNGTK 225
Query: 1299 REQSRDGS-RHPGFHQEDRASHGHSADSSRQSGTHHTESSSHGQAVSSHEQARSSPGERH 1357
+ G+ G D + G+ AD G+ E G S ++ G+ H
Sbjct: 226 EAEVTPGTGEDAGLDNSDGSPSGNGADEDEDEGSGDDEDEEAGNGKDSSNNSKGQEGQDH 285
Query: 1358 GSRHQQSADSSRHSGIGHRQASSAVRDSGHRGSSGSQVTNSEGHS----EDS------DT 1407
G + ++S D H G + + SE +S ED+ DT
Sbjct: 286 GKEDDHDSSIGQNSDSKEYYDPEGKEDP-HNEVDGDKTSKSEENSAGIPEDNGSQRIEDT 344
Query: 1408 QSVSAHGQAGPHQQSHKES---ARGQS--------GESSGRSRSFLYQVSSHEQSESTHG 1456
Q ++ + KES A G+S G SSG +R+ +V + + G
Sbjct: 345 QKLNHRESKRVENRITKESETHAVGKSQDKGIEIKGPSSG-NRNITKEVGKGNEGKEDKG 403
Query: 1457 QTAPSTG-GRQGSRHEQARNSSRHSASQDGQDTIRGHPGS---SRGGRQGSYHEQSVDRS 1512
Q G G ++ E S+ G + GS S G + ++S+
Sbjct: 404 QHGMILGKGNVKTQGEVVNIEGPGQKSEPGNKVGHSNTGSDSNSDGYDSYDFDDKSMQGD 463
Query: 1513 GHSGYHHSHTTPQGRSDASHGQSGPRSASRQTRNEEQSGDGSRHSGSRHHEPSTRAGSSR 1572
+ S+ S++ + S AS + + +G+GS G+ + + + ++
Sbjct: 464 DPNSSDESNGNDDANSESDNNSSSRGDASYNSDESKDNGNGSDSKGAEDDDSDSTSDTNN 523
Query: 1573 HSQVGQGESAGS---KTSRRQGSSVSQDRDSEGHSEDSERR----SESASRNHYGSAREQ 1625
G G + K+ +G S S D DS S S+ S+S+ N +
Sbjct: 524 SDSNGNGNNGNDDNDKSDSGKGKSDSSDSDSSDSSNSSDSSDSSDSDSSDSNSSSDSDSS 583
Query: 1626 SRHGSRNPRSHQEDRASHGHSAESSRQSGTRHAETSSGGQAASSQEQARSSPGERHGSRH 1685
S + S D ++ S++SS S + + SS ++ SS+ ++ SS
Sbjct: 584 DSDSSDSSDSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSKSDSSKSESDSS--------- 634
Query: 1686 QQSADSSTDSGTGRRQDSSVVGDSGNRGSSGSQASDSEGHSEESDTQSVSAHGQAGPHQQ 1745
+DS +DS DSS DS + S+ S +SDS S+ SD+ S S +
Sbjct: 635 --DSDSKSDSSDSNSSDSSDNSDSSD-SSNSSNSSDSSDSSDSSDSSSSSDSSNSSDSSD 691
Query: 1746 SHQESTRGQSGERSGRSGSFLYQVSTHEQSESAHGRTGPSTGGRQRSRHEQARDSSRHSA 1805
S S +S + S S S S S S+ + S+ S + DSS S
Sbjct: 692 SSDSSNSSESSDSSDSSDSDSSDSSDSSNSNSSDSDSSNSSDSSDSSNSSDSSDSSDSSN 751
Query: 1806 SQEGQDTIRGHPGSSRGGRQGSHYEQSVDSSGHSGSHHSHTTSQERSDVSRGQSGSRSVS 1865
S + D+ S+ S DSS S S S +S + S S S
Sbjct: 752 SSDSSDS-----------SDSSNSSDSSDSSDSSDSSDSSNSSDSNDSSNSSDSSDSSNS 800
Query: 1866 RQTRNEKQSGDGSRHSGSRHHEASSRADSSRHSQVGQGQSSGPRTSRNQGSSVSQDSDSQ 1925
+ N S D S S S ++S+ +DSS S +S +S + SS DSDS
Sbjct: 801 SDSSNSSDSSDSSDSSDS---DSSNSSDSSNSSDSSDSSNSSD-SSDSSDSSDGSDSDSS 856
Query: 1926 GHSEDSERWSGSASRNHLGSAWEQSRDGSRHPGSHHEDRAGHGHSADSSRQSGTRHTESS 1985
S DS S S+ + ++ + S + S+ D + +S+DS + ++SS
Sbjct: 857 NRS-DSSNSSDSSDSSDSSNSSDSSDSSDSNESSNSSDSSDSSNSSDSDSSDSSNSSDSS 915
Query: 1986 SRGQAASSHEQARSSAGERHGSHHQLQSADSSRHSGIGHGQASSAVRDSGHRG-YSGSQA 2044
++ S E + SS + S S+DSS S + SS DS + S S +
Sbjct: 916 DSSNSSDSSESSNSS--DNSNSSDSSNSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSNS 973
Query: 2045 SDSEGHSEDSDTQSVSAQGKAGPHQQSHKESARGQSGESSGRSGSFLYQVSTHEQSESTH 2104
SDS S SD+ S + S S S +SS S S S+ + S
Sbjct: 974 SDSSDSSNSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSNSSDSSNSSDSSNSSDS 1033
Query: 2105 GQSAPSTGGRQGSHYDQAQDSSRHSASQEGQDTIRGHPGPSRGGRQGSHQEQSVDRSGHS 2164
S+ S+ S + DSS S S + D+ S S D S S
Sbjct: 1034 SDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDS-----------SDSSDSSDSSDSSDSS 1082
Query: 2165 GSHHSHTTSQGRSDASRGQSGSRSASRKTYDKEQSGDGSRHSGSHHHEASSWADSSRHSL 2224
S S +S + S S S + D S D S S S SS + S +S
Sbjct: 1083 ESSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSS 1142
Query: 2225 VGQGQSSGPRTSRPRGSSVSQDSDSEGHSEDSERRSGSASRNHHGSAQEQSRDGSRHPRS 2284
S +S SS S DS S DS S S+ + + + S S
Sbjct: 1143 DSSDSSESSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSS 1202
Query: 2285 HHEDRAGHGHSAESSRQSGTHHAENSSGGQAASSHEQARSSAGERHGSHHQQSADSSRHS 2344
D + S++SS S + + +SS +S + S+ + S S+DSS +
Sbjct: 1203 DSSDSSDSSDSSDSSDSSDSSDSSDSSDSNESSDSSDSSDSSDSSNSSDSSDSSDSSDST 1262
Query: 2345 GIGHGQASSAVRDSGHRGSSGSQASDSEGHSEDSDT 2380
+ ++ S + G+ + SDS+ SE SD+
Sbjct: 1263 SDSNDESDSQSKS----GNGNNNGSDSDSDSEGSDS 1294
Score = 261 bits (667), Expect = 1e-68
Identities = 306/1361 (22%), Positives = 509/1361 (37%), Gaps = 145/1361 (10%)
Query: 1254 QEQSSGSRTSRHQGSSVSQ-DSDSERHSDDSERLSGSASRNHHGSSREQSRDGSRHPGFH 1312
Q++ + S T + G V + D + ++ D + G+ S+ + + S +
Sbjct: 45 QDELNASGTIKESGVLVHEGDRGRQENTQDGHKGEGNGSK----WAEVGGKSFSTYSTLA 100
Query: 1313 QEDRASHGHSADSSR-----QSGTHHTESSSHGQAVSSHEQARSSPGERHGSRHQQSADS 1367
E+ G + D+ + G H E + + + G + S + D
Sbjct: 101 NEEGNIEGWNGDTGKAETYGHDGIHGKEENITANGIQGQVSIIDNAGATNRSNTNGNTDK 160
Query: 1368 SRHSG----IGHRQASSAVRDSGHRGSSGSQVTNSEGHSEDSDTQSVSAHGQAGPHQQSH 1423
+ +G GH + + V++ G + + + T++E ++ ++ + P S
Sbjct: 161 NTQNGDVGDAGHNEDVAVVQEDGPQVAGSNNSTDNEDEIIENSCRNEGNTSEITPQINSK 220
Query: 1424 KESARGQ-----SGESSGRSRSFLYQVSSHEQSESTHGQTAPSTGGRQGSRHEQARN--- 1475
+ + +GE +G S + S S +G G E+A N
Sbjct: 221 RNGTKEAEVTPGTGEDAGLDNS--------DGSPSGNGADEDEDEGSGDDEDEEAGNGKD 272
Query: 1476 SSRHSASQDGQDTIRGHPGSSRGGRQGSYHEQSVDRSGHSGYHHSHTTPQGRSDASHGQS 1535
SS +S Q+GQD G++ H+ S+ ++ S ++ P+G+ D +
Sbjct: 273 SSNNSKGQEGQDH----------GKEDD-HDSSIGQNSDSKEYYD---PEGKEDPHNEVD 318
Query: 1536 GPRSASRQTRNEEQSGDGSRHSGSRHHEPSTRAGSSRHSQVGQGESAGSKTSRRQGSSVS 1595
G +++ ++EE S +GS+ E + + H + + E+ +K S S
Sbjct: 319 GDKTS----KSEENSAGIPEDNGSQRIEDTQKLN---HRESKRVENRITKESETHAVGKS 371
Query: 1596 QDRDSE--GHSEDSERRSESASRNHYGSAREQSRHG----SRNPRSHQEDRASHGHSAES 1649
QD+ E G S + ++ + + G ++ +HG N ++ E G +S
Sbjct: 372 QDKGIEIKGPSSGNRNITKEVGKGNEGK-EDKGQHGMILGKGNVKTQGEVVNIEGPGQKS 430
Query: 1650 SRQSGTRHAETSSGGQAAS-------SQEQARSSPGERHGSRHQQSADSSTDSGTGRRQD 1702
+ H+ T S + + P S A+S +D+ + R D
Sbjct: 431 EPGNKVGHSNTGSDSNSDGYDSYDFDDKSMQGDDPNSSDESNGNDDANSESDNNSSSRGD 490
Query: 1703 SSVVGDSGNRGSSGSQASDSEGHSEES--DTQSVSAHGQAGPHQQSHQESTRGQSGERSG 1760
+S D +GS + +E +S DT + ++G + +S G+ S
Sbjct: 491 ASYNSDESKDNGNGSDSKGAEDDDSDSTSDTNNSDSNGNGNNGNDDNDKSDSGKGKSDSS 550
Query: 1761 RSGSFLYQVSTHEQSESAHGRTGPSTGGRQRSRHEQARDSSRHSASQEGQDTIRGHPGSS 1820
S S + S+S+ S+ S + + S S+ + D+
Sbjct: 551 DSDSS----DSSNSSDSSDSSDSDSSDSNSSSDSDSSDSDSSDSSDSDSSDS-------- 598
Query: 1821 RGGRQGSHYEQSVDSSGHSGSHHSHTTSQERSDVSRGQSGSR-SVSRQTRNEKQSGDGSR 1879
S+ S DSS S S S +S +SD S+ +S S S S+ ++ S D S
Sbjct: 599 ------SNSSDSSDSSDSSDSSDSSDSSDSKSDSSKSESDSSDSDSKSDSSDSNSSDSSD 652
Query: 1880 HSGSRHHEASSRADSSRHSQVGQGQSSGPRTSRNQGSSVSQDSDSQGHSEDSERWSGSAS 1939
+S S SS + S S SS +S + SS S DS + S DS S S S
Sbjct: 653 NSDSSDSSNSSNSSDSSDSSDSSDSSSSSDSSNSSDSSDSSDSSNSSESSDSSDSSDSDS 712
Query: 1940 RNHLGSAWEQSRDGSRHPGSHHEDRAGHGHSADSSRQSGTRHTESSSRGQAASSHEQARS 1999
+ S+ S D S D + S+DSS S + + SS +S +
Sbjct: 713 SDSSDSSNSNSSDSDSSNSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSNSSDSSDSSD 772
Query: 2000 SAGERHGSHHQLQSADSSRHSGIGHGQASSAVRDSGHRGYSGSQASDSEGHSEDSDTQSV 2059
S+ S+DSS S SS DS + S S +SDS S+ SD+ S
Sbjct: 773 SS----------DSSDSSNSSDSNDSSNSSDSSDSSNSSDS-SNSSDSSDSSDSSDSDS- 820
Query: 2060 SAQGKAGPHQQSHKESARGQSGESSGRSGSFLYQVSTHEQSESTHGQSAPSTGGRQGSHY 2119
S S S +SS S S + S+S+ G + S+ S+
Sbjct: 821 ---------SNSSDSSNSSDSSDSSNSSDS-------SDSSDSSDGSDSDSSNRSDSSNS 864
Query: 2120 DQAQDSSRHSASQEGQDTIRGHPGPSRGGRQGSHQEQSVDRSGHSGSHHSHTTSQGRSDA 2179
+ DSS S S + D S + S+ S D S S S S +++ S
Sbjct: 865 SDSSDSSDSSNSSDSSD--------SSDSNESSNSSDSSDSSNSSDSDSSDSSNSSDSSD 916
Query: 2180 SRGQSGSRSASRKTYDKEQSGDGSRHSGSHHHEASSWADSSRHSLVGQGQSSGPRTSRPR 2239
S S S +S + + S + S ++S+ +DSS S SS S
Sbjct: 917 SSNSSDSSESSNSSDNSNSSDSSNSSDSSDSSDSSNSSDSSNSS-----DSSNSSDSSDS 971
Query: 2240 GSSVSQDSDSEGHSEDSERRSGSASRNHHGSAQEQSRDGSRHPRSHHEDRAGHGHSAESS 2299
SS S DS + S DS S S+ + ++ + S S+ D + S+ SS
Sbjct: 972 NSSDSSDSSNSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSNSSDSSNSSDSSNSS 1031
Query: 2300 RQSGTHHAENSSGGQAASSHEQARSSAGERHGSHHQQSADSSRHSGIGHGQASSAVRDSG 2359
S + + +SS +S + +S+ S S+DSS S SS DS
Sbjct: 1032 DSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSESSDSSDS- 1090
Query: 2360 HRGSSGSQASDSEGHSEDSDTQSVSAHGQAGPHQQSHQESTRGRSAGRSGRSGSFLYQVS 2419
S+ S +SDS S+ SD+ S + S S S+ S S S S
Sbjct: 1091 ---SNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSSDS 1147
Query: 2420 THEQSESAHGRTGTSTGGRQGSHHKQARDSSRHSTSQEGQDTIHGHPGSSSGGRQGSHYE 2479
+ S + S+ S + DSS S S + D+ S S
Sbjct: 1148 SESSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSS-------- 1199
Query: 2480 QLVDRSGHSGSHHSHTTSQGRSDASHGHSGSRSASRQTRNDEQSGDGSRHSGSRHHEASS 2539
D S S S S +S + S S S ++ + S D S S S ++S
Sbjct: 1200 ---DSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSNESSDSSDSSDSSDSSNS--SDSSD 1254
Query: 2540 RADSSGHSQVGQGQSEGPRTSRNWGSSFSQDSDSQGHSEDS 2580
+DSS + +S+ S N G++ DSDS DS
Sbjct: 1255 SSDSSDSTSDSNDESDSQSKSGN-GNNNGSDSDSDSEGSDS 1294
Score = 261 bits (666), Expect = 1e-68
Identities = 311/1314 (23%), Positives = 498/1314 (37%), Gaps = 125/1314 (9%)
Query: 130 RRNNRKGNKGRSKSPR--ETGGKRHESSSEKKERKGY-----SPTHREEEYGKNHHNSSK 182
+ N + G+KG + E GGK + S +G T + E YG H
Sbjct: 69 QENTQDGHKGEGNGSKWAEVGGKSFSTYSTLANEEGNIEGWNGDTGKAETYG--HDGIHG 126
Query: 183 KEKNKTENTRLGDNRKRLSERLEEKEDNEEGVYDYENTGRMTQKWIQSGHIATYYTIQDE 242
KE+N T N G + + G + NT T K Q+G + D
Sbjct: 127 KEENITANGIQG----------QVSIIDNAGATNRSNTNGNTDKNTQNGDVG------DA 170
Query: 243 AYDTTDSLLEEN--KIYERSRSSDGKSSSQVNRSRHE-NTSQVPLQESRTRKRRGSRVSQ 299
++ ++++E+ ++ + S+D + N R+E NTS++ Q + KR G++ ++
Sbjct: 171 GHNEDVAVVQEDGPQVAGSNNSTDNEDEIIENSCRNEGNTSEITPQINS--KRNGTKEAE 228
Query: 300 DRDSEGHSEDSERHSGSASRNHHGSAWEQSRDGSRHPRSHDEDRASHGHSADSSRQS--- 356
G + GS S N A E +GS DED + G+ DSS S
Sbjct: 229 VTPGTGEDAGLDNSDGSPSGN---GADEDEDEGS----GDDEDEEA-GNGKDSSNNSKGQ 280
Query: 357 -----GTRHAETSSRGQTASSHE----QARSSP-----GERHGSGHQQSADSSRHSATGR 402
G SS GQ + S E + + P G++ + SA + + R
Sbjct: 281 EGQDHGKEDDHDSSIGQNSDSKEYYDPEGKEDPHNEVDGDKTSKSEENSAGIPEDNGSQR 340
Query: 403 GQASSAVSDRGHRGSSGSQASDSEGHSEN-SDTQSVSGHGKAGLRQQSHQESTRGRSG-E 460
+ + ++ R + +SE H+ S + + G + + +E +G G E
Sbjct: 341 IEDTQKLNHRESKRVENRITKESETHAVGKSQDKGIEIKGPSSGNRNITKEVGKGNEGKE 400
Query: 461 RSGRSGSSLYQ--VSTHEQPDSAHGRTGTSTGGRQGSHHEQARDSSRHSASQEGQDTIRG 518
G+ G L + V T + + G S G + H DS+ +G D+
Sbjct: 401 DKGQHGMILGKGNVKTQGEVVNIEGPGQKSEPGNKVGHSNTGSDSN-----SDGYDSYDF 455
Query: 519 HPGSSRGGRQGSHHEQSVNRSGHSGSHHSHTTSQGRSDASHGQSGSRSASRQTRNEEQSG 578
S +G S E + N +S S ++ S R DAS+ S+ +G
Sbjct: 456 DDKSMQGDDPNSSDESNGNDDANSESDNN---SSSRGDASYNSDESKD----------NG 502
Query: 579 DGTRHSGSRHHEASSQADSSRHSQVGQGQSSGP---RTSRNQGSSVSQDSDSQ--GHSED 633
+G+ G+ ++ S +D++ G G + ++ +G S S DSDS +S D
Sbjct: 503 NGSDSKGAEDDDSDSTSDTNNSDSNGNGNNGNDDNDKSDSGKGKSDSSDSDSSDSSNSSD 562
Query: 634 SERWSGSASRNHHGSAQEQSRDGSRHPRSHHE--DRAGHGHSADSSRKSGTRHTQNSSSG 691
S S S S + + S+ S D S + D + S+DSS S + + +SS
Sbjct: 563 SSDSSDSDSSDSNSSSDSDSSDSDSSDSSDSDSSDSSNSSDSSDSSDSSDSSDSSDSSDS 622
Query: 692 QAASSHEQARSSAGERHGSRHQLQSADSSRHSGTGHGQASSAVRDSGHRGSSGSQATDSE 751
++ SS ++ SS + S+DSS +S + SS DS S ++DS
Sbjct: 623 KSDSSKSESDSSDSDSKSDSSDSNSSDSSDNSDSSDSSNSSNSSDS-------SDSSDSS 675
Query: 752 GHSEDSDTQSVSGHGQAGHHQQSHQESARDRSGERSRRSGSFLYQVSTHKQSESSHGWTG 811
S SD+ + S + S + S S + S S S+S +
Sbjct: 676 DSSSSSDSSNSSDSSDSSDSSNSSESSDSSDSSDSDSSDSS---DSSNSNSSDSDSSNSS 732
Query: 812 PSTGVRQGSHHEQARDNSRHSASQDGQDTIRGHPGSSRRGRQGSHHEQSVDRSGHSGSHH 871
S+ S + D+S S S D D+ +S S S D S S S+
Sbjct: 733 DSSDSSNSSDSSDSSDSSNSSDSSDSSDS-----SNSSDSSDSSDSSDSSDSSNSSDSND 787
Query: 872 SHTTSQGRSDASRGQSGSRSASRTTRNEEQSRDGSRHSGSRHHEASSHADISRHSQAGQG 931
S +S SD+S S S+ + ++ D S S S + SS + S S
Sbjct: 788 SSNSSDS-SDSSNSSDSSNSSDSSDSSDSSDSDSSNSSDSSNSSDSSDSSNSSDSSDSSD 846
Query: 932 QSEG--SRTSRRQGSSVSQDSDSEGHSEDSERWSGSASRNHRGSAQEQSRHGSRHPRSHH 989
S+G S +S R SS S DS S +S S S+ N ++ + S
Sbjct: 847 SSDGSDSDSSNRSDSSNSSDSSDSSDSSNSSDSSDSSDSNESSNSSDSS----------D 896
Query: 990 EDRAGHGHSADSSRQSGTPHAETSSGGQAASSHEQARSSPGERHGSRHQQSADSSRHSGI 1049
+ S+DSS S + + SS +S+ +S + S S+DSS S
Sbjct: 897 SSNSSDSDSSDSSNSSDSSDSSNSSDSSESSNSSDNSNSSDSSNSSDSSDSSDSSNSSDS 956
Query: 1050 PRRQASSAVRDSGHWGSSGSQASDSEGHSEESDTQSVSGHGQDGPHQQSHQESARDWSGG 1109
SS DS SS S S + S +S S S D + +S+
Sbjct: 957 SNSSDSSNSSDSSDSNSSDSSDSSNSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSS 1016
Query: 1110 RSGRSGSFIYQVSTHEQSESAHGRTRTSTGRRQGSHHEQARDSSRHSASQEGQDTIRAHP 1169
S S + ++ + S+S+ S+ S + DSS S S + D+ +
Sbjct: 1017 NSSDSSNSSDSSNSSDSSDSS-----DSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSD 1071
Query: 1170 GSRRGGRQGSHHEQSVDRSGHSGSHHSHTTSQGRSDASHGQSGSRSASRQTRKDKQSGDG 1229
S S +S D S S S S +S + S S S + S D
Sbjct: 1072 SS--DSSDSSDSSESSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDS 1129
Query: 1230 SRHSGSRHHEAASWADSSRHSQVGQEQSSGSRTSRHQGSSVSQDSDSERHSDDSERLSGS 1289
S S S +S + S S + S S +S SS S DS +S DS S S
Sbjct: 1130 SDSSDSSDSSNSSDSSDSSESSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDS 1189
Query: 1290 ASRNHHGSSREQSRDGSRHPGFHQEDRASHGHSADSSRQSGTHH----TESSSHGQAVSS 1345
+ + S + S D + S+DSS S ++ ++SS + +S
Sbjct: 1190 SDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSNESSDSSDSSDSSDSSNS 1249
Query: 1346 HEQARSSPGERHGSRHQQSADSSRHSGIGHRQASSAVRDSGHRGSSGSQVTNSE 1399
+ + SS S +DS SG G+ S + DS GS + T+ +
Sbjct: 1250 SDSSDSSDSSDSTSDSNDESDSQSKSGNGNNNGSDS--DSDSEGSDSNHSTSDD 1301
Score = 256 bits (655), Expect = 2e-67
Identities = 295/1314 (22%), Positives = 487/1314 (37%), Gaps = 117/1314 (8%)
Query: 2655 GSHHQQSADSSRHSGIGHGQASSAVRDSGHRGYSGSQASDNEGHSE--DSDTQSVSAHGQ 2712
G +Q H G G+G + V YS ++ EG+ E + DT +G
Sbjct: 64 GDRGRQENTQDGHKGEGNGSKWAEVGGKSFSTYS--TLANEEGNIEGWNGDTGKAETYGH 121
Query: 2713 AGSHQQSHQESARGRSGETSGHSGSFLYQVSTHEQSESSHGWTGPSTR----GRQGSRHE 2768
G H + +A G G+ S + + +++G T +T+ G G +
Sbjct: 122 DGIHGKEENITANGIQGQVS------IIDNAGATNRSNTNGNTDKNTQNGDVGDAGHNED 175
Query: 2769 QA---QDSSRHSASQ---DGQDTIRGHPGSSRGGRQGYHHEHSVDSSGHSGSHHSHTTSQ 2822
A +D + + S D +D I + + G + + S +G+ + T
Sbjct: 176 VAVVQEDGPQVAGSNNSTDNEDEIIENSCRNEGNTSEITPQIN---SKRNGTKEAEVTPG 232
Query: 2823 GRSDASRGQSGSRSASRTTRNEEQSGDGSRHSGSRHHEASTHADISRHSQAVQGQSEGSR 2882
DA S + +E G G EA D S +S+ +GQ G
Sbjct: 233 TGEDAGLDNSDGSPSGNGADEDEDEGSGD----DEDEEAGNGKDSSNNSKGQEGQDHGKE 288
Query: 2883 RSRRQGSSVSQDSDS------EGHSEDSERWSGS-ASRNHHGSAQEQLRDGSRHPRSHQE 2935
SS+ Q+SDS EG + G S++ SA +GS+ R
Sbjct: 289 DDH--DSSIGQNSDSKEYYDPEGKEDPHNEVDGDKTSKSEENSAGIPEDNGSQ--RIEDT 344
Query: 2936 DRAGHGHSADSSRQSGTRHTQTSSGGQAASSHEQARS-SAGERH-----GSHHQQSADSS 2989
+ H S + T+ ++T + G++ + + S+G R+ G ++ D
Sbjct: 345 QKLNHRESKRVENRI-TKESETHAVGKSQDKGIEIKGPSSGNRNITKEVGKGNEGKEDKG 403
Query: 2990 RHSGI----------------GHGQASSAVRDSGHRGYSGSQASDNEGHSEDSDTQSVSA 3033
+H I G GQ S GH +GS ++ + S D D +S+
Sbjct: 404 QHGMILGKGNVKTQGEVVNIEGPGQKSEPGNKVGHSN-TGSDSNSDGYDSYDFDDKSMQG 462
Query: 3034 HGQAGSHQQSHQESARGRSGETSGHSGSFLYQVSTHEQSESSHGWTGPSTRGRQGSRHEQ 3093
S + + + A S S G +++ ES G ++G + +
Sbjct: 463 DDPNSSDESNGNDDANSESDNNSSSRGD-----ASYNSDESKDNGNGSDSKGAEDDDSDS 517
Query: 3094 AQDSSRHSASQYGQDTIRGHPGSSRGGRQGYHHEHSVDSSGHSGSHHSHTTSQGRSDASR 3153
D++ ++ G + + S G +G DSS S S S +S S S
Sbjct: 518 TSDTNNSDSNGNGNNGNDDNDKSDSG--KGKSDSSDSDSSDSSNSSDSSDSSDSDSSDSN 575
Query: 3154 GQSGSRSASRTTRNEEQSGDSSRHSVSRHHEASTHADISRHSQAVQGQSEGSRRSRRQGS 3213
S S S+ + + S S + S ++S +D S S + +S+ S+
Sbjct: 576 SSSDSDSSDSDSSDSSDSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSKSDSSKSESDSSD 635
Query: 3214 SVSQDSDSEGHSEDSERWSGSASRNHRGSVQEQSRHGSRHPRSHHEDRAGHGHSADRSRQ 3273
S S+ S+ +S DS S S+ ++ + + S S D + S+D S
Sbjct: 636 SDSKSDSSDSNSSDSSDNSDSSDSSNSSNSSDSSDSSDSSDSSSSSDSSNSSDSSDSSDS 695
Query: 3274 SGTRHAETSSGGQAASSHEQARSSPGERHGSRHQQSADSSRHSGIPRGQASSAVRDSRHW 3333
S + + SS + S + + SS S S+DSS S SS +S
Sbjct: 696 SNSSESSDSSDSSDSDSSDSSDSSNSNSSDSDSSNSSDSSDSSNSSDSSDSSDSSNS--- 752
Query: 3334 GSSGSQASDSEGHSEESDTQSVSGHGQAGPHQQSHQESARDRSGGRSGRSGSFLYQVSTH 3393
S S +SDS S+ SD+ S + S+ S S S S S ++
Sbjct: 753 -SDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSNDSSNSSDSSDSSNSSDSS----NSS 807
Query: 3394 EQSESAHGRTRTSTGRRQGSHHEQARDSSRHSASQEGQDTIRGHPGSSRRGRQGSHYEQS 3453
+ S+S+ S+ S+ + DSS S S + D+ G S S+ S
Sbjct: 808 DSSDSSDSSDSDSSNSSDSSNSSDSSDSSNSSDSSDSSDSSDGSDSDSSNRSDSSNSSDS 867
Query: 3454 VDRSGHSGSHHSHTTSQGRSDASRGQSGSRSASRQTRNDEQSGDGSRHSWSHHHEASTQA 3513
D S S S + S SD++ + S S+ +D S D S +S +
Sbjct: 868 SDSSDSSNS----SDSSDSSDSNESSNSSDSSDSSNSSDSDSSDSSN--------SSDSS 915
Query: 3514 DSSRHSQSGQGQSAGPRTSRNQGSSVSQDSDSQGHSEDSERWSGSASRNHRGSAQEQSRD 3573
DSS S S + ++ ++ + S+ S SDS S S+ + S S N S+ S D
Sbjct: 916 DSSNSSDSSESSNSSDNSNSSDSSNSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSNSSD 975
Query: 3574 GSRHPTSHHEDRAGHGHSAESSRQSGTHHAENSSGGQAASSHEQARSSAGERHGSHHQQS 3633
S +S+ D + S++SS S + ++ +SS +S + S+ S+ S
Sbjct: 976 SS--DSSNSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSNSSDSSNSSDSSNSSDS 1033
Query: 3634 ADSSRHSGIGHGQASSAVRDSGHRGSSGSQASDSEGHSEDSDTQSVSAHGQAGPHQQSHQ 3693
+DSS S SS DS + S S +SDS S+ SD+ S ++ S
Sbjct: 1034 SDSSDSSDSSDSSDSSDSSDSSN-SSDSSDSSDSSDSSDSSDSSDSSDSSESSDSSDSSN 1092
Query: 3694 ESTRGRSAGRSGRSGSFLYQVSTHEQSESAHGRAGPSTGGRQGSRHEQARDSSRHSASQE 3753
S S+ S S S S+ S + S+ S + DSS S S +
Sbjct: 1093 SSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSSDSSESSD 1152
Query: 3754 GQDTIRGHPGSRRGGRQGSYHEQSVDRSGHSGSHHSHTTSQGRSDASHGQSGSRSASRET 3813
D+ S D S S S S +S + + S S S ++
Sbjct: 1153 SSDS-----------------SDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDS 1195
Query: 3814 RNEEQSGDGSRHSGSRHHEASTQADSSRHSQSGQGESAGSRRSRRQGSSVSQDSDSEAYP 3873
+ S D S ++S +DSS S S + + S S SDS
Sbjct: 1196 SDSSDSSDSS--------DSSDSSDSSDSSDSSDSSDSSDSSDSNESSDSSDSSDSSDSS 1247
Query: 3874 EDSERRSESASRNHHGSSREQSRDGSRHPGSSHRDTASHVQSSPVQSDSSTAKE 3927
S+ S S + S ++S S+ ++ + S S S+ ST+ +
Sbjct: 1248 NSSDSSDSSDSSDSTSDSNDESDSQSKSGNGNNNGSDSDSDSEGSDSNHSTSDD 1301
Score = 253 bits (647), Expect = 2e-66
Identities = 301/1339 (22%), Positives = 475/1339 (35%), Gaps = 141/1339 (10%)
Query: 730 ASSAVRDSG---HRGSSGSQATDSEGHSEDSDTQSVSGHGQAGHHQQSHQESARDRSGER 786
AS +++SG H G G Q +GH + + + G
Sbjct: 50 ASGTIKESGVLVHEGDRGRQENTQDGHKGEGNGSKWAEVG-------------------- 89
Query: 787 SRRSGSFLYQVSTHKQSESS-HGWTGPSTGVRQGSHHEQARDNSRHSASQ--DGQDTIRG 843
G ST E + GW G TG + H+ + + GQ +I
Sbjct: 90 ----GKSFSTYSTLANEEGNIEGWNG-DTGKAETYGHDGIHGKEENITANGIQGQVSIID 144
Query: 844 HPGSSRRGRQGSHHEQSVDRSGHSGSHHSHTTSQGRSDASRGQSGSRSASRTTRNEEQSR 903
+ G++ R + +++ + H+ + + D G + S + T +E
Sbjct: 145 NAGATNRSNTNGNTDKNTQNGDVGDAGHNEDVAVVQED---GPQVAGSNNSTDNEDEIIE 201
Query: 904 DGSRHSGSRHH---EASSHADISRHSQAGQGQSEGSRTSRRQGSSVSQDSDSE-----GH 955
+ R+ G+ + +S + ++ ++ G E + GS +D + G
Sbjct: 202 NSCRNEGNTSEITPQINSKRNGTKEAEVTPGTGEDAGLDNSDGSPSGNGADEDEDEGSGD 261
Query: 956 SEDSERWSGSASRNHRGSAQEQSRHGSRHPRSHHEDRAGHGHSADSSRQ-----SGTPHA 1010
ED E +G S N+ + + G H + D + G ++DS PH
Sbjct: 262 DEDEEAGNGKDSSNN-----SKGQEGQDHGKEDDHD-SSIGQNSDSKEYYDPEGKEDPHN 315
Query: 1011 ETSSGGQAASSHEQARSSPGERHGSRHQQSADSSRH-------SGIPRRQASSAVRDSGH 1063
E G + + S E + P E +GS+ + H + I + + AV S
Sbjct: 316 EVD-GDKTSKSEENSAGIP-EDNGSQRIEDTQKLNHRESKRVENRITKESETHAVGKSQD 373
Query: 1064 WG------SSGSQ------ASDSEGHSEESDTQSVSGHGQ----------DGPHQQSH-- 1099
G SSG++ +EG ++ + G G +GP Q+S
Sbjct: 374 KGIEIKGPSSGNRNITKEVGKGNEGKEDKGQHGMILGKGNVKTQGEVVNIEGPGQKSEPG 433
Query: 1100 QESARDWSGGRSGRSGSFIYQVSTHEQSESAHGRTRTSTGRRQGSHHEQARDSSRHSASQ 1159
+ +G S G Y + S G + SSR AS
Sbjct: 434 NKVGHSNTGSDSNSDGYDSYDFDDKSMQGDDPNSSDESNGNDDANSESDNNSSSRGDASY 493
Query: 1160 EGQDTIRAHPGSRRGGRQGSHHEQSVD--RSGHSGSHHSHTTSQGRSDASHGQSGSRSAS 1217
++ GS G + + + D S +G+ ++ +SD+ G+S S +
Sbjct: 494 NSDESKDNGNGSDSKGAEDDDSDSTSDTNNSDSNGNGNNGNDDNDKSDSGKGKSDSSDSD 553
Query: 1218 RQTRKDKQSGDGSRHSGSRHHEAASWADSSRHSQVGQEQSSGSRTSRHQGSSVSQD-SDS 1276
+ S S S ++S +DSS S S +S SS S D SDS
Sbjct: 554 SSDSSNSSDSSDSSDSDSSDSNSSSDSDSSDSDSSDSSDSDSSDSSNSSDSSDSSDSSDS 613
Query: 1277 ERHSDDSERLSGSASRNHHGSSREQSRDGSRHPGFHQEDRASHGHSADSSRQSGTHHTES 1336
SD S+ S S+ S + D S D + S++SS S + +
Sbjct: 614 SDSSDSSDSKSDSSKSESDSSDSDSKSDSSDSNSSDSSDNSDSSDSSNSSNSSDSSDSSD 673
Query: 1337 SSHGQAVSSHEQARSSPGERHGSRHQQSADSSRHSGIGHRQASSAVRDSGHRGSSGSQVT 1396
SS + S + S S +S+DSS S SS DS + SS S +
Sbjct: 674 SSDSSSSSDSSNSSDSSDSSDSSNSSESSDSSDSSD----SDSSDSSDSSNSNSSDSDSS 729
Query: 1397 NSEGHSEDSDTQSVSAHGQAGPHQQSHKESARGQSGESSGRSRSFLYQVSSHEQSESTHG 1456
NS S+ S++ S + S S S +SS S S SS + S
Sbjct: 730 NSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDS---SDSSDSSNSSDSN 786
Query: 1457 QTAPSTGGRQGSRHEQARNSSRHSASQDGQDTIRGHPGSSRGGRQGSYHEQSVDRSGHSG 1516
++ S+ S + NSS S S D D+ + S S S D S S
Sbjct: 787 DSSNSSDSSDSSNSSDSSNSSDSSDSSDSSDSDSSNSSDSSNSSDSSDSSNSSDSSDSS- 845
Query: 1517 YHHSHTTPQGRSDASHGQSGPRSASRQTRNEEQSGDGSRHSGSRHHEPSTRAGSSRHSQV 1576
SD S S RS S + + S D S S S S + +S S
Sbjct: 846 ---------DSSDGSDSDSSNRSDSSNSSDSSDSSDSSNSSDSSDSSDSNESSNSSDS-- 894
Query: 1577 GQGESAGSKTSRRQGSSVSQDRDSEGHSEDSERRSESASRNHYGSAREQSRHGSRNPRSH 1636
+S+ S S SS S D +S DS S S+ ++ + S + S+
Sbjct: 895 --SDSSNSSDSDSSDSSNSSDSSDSSNSSDSSESSNSSDNSNSSDSSNSSDSSDSSDSSN 952
Query: 1637 QEDRASHGHSAESSRQSGTRHAETSSGGQAASSQEQARSSPGERHGSRHQQSADSSTDSG 1696
D ++ S+ SS S + +++S ++ S + + SS S+DSS S
Sbjct: 953 SSDSSNSSDSSNSSDSSDSNSSDSSDSSNSSDSSDSSDSS----------DSSDSSDSSN 1002
Query: 1697 TGRRQDSSVVGDSGNRGSSGSQASDSEGHSEESDTQSVSAHGQAGPHQQSHQESTRGQSG 1756
+ DSS DS N S S +SDS S+ SD+ S + S S S
Sbjct: 1003 SSDSSDSSDSSDSSN-SSDSSNSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSS 1061
Query: 1757 ERSGRSGSFLYQVSTHEQSESAHGRTGPSTGGRQRSRHEQARDSSRHSASQEGQDTIRGH 1816
+ S S S S+S+ S+ S + DSS S S + D+
Sbjct: 1062 DSSDSSDS----------SDSS-----DSSDSSDSSESSDSSDSSNSSDSSDSSDS---- 1102
Query: 1817 PGSSRGGRQGSHYEQSVDSSGHSGSHHSHTTSQERSDVSRGQSGSRSVSRQTRNEKQSGD 1876
S S S DSS S S S +S + S S S + + S D
Sbjct: 1103 -SDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSSDSSESSDSSDSSDSSD 1161
Query: 1877 GSRHSGSRHHEASSRADSSRHSQVGQGQSSGPRTSRNQGSSVSQDSDSQGHSEDSERWSG 1936
S S S SS + +S S S +S + SS S DS S DS S
Sbjct: 1162 SSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSD 1221
Query: 1937 SASRNHLGSAWEQSRDGSRHPGSHHEDRAGHGHSADSSRQSGTRHTESSSRGQAASSHEQ 1996
S+ + + E S S + + S+DSS + + ES S+ ++ + +
Sbjct: 1222 SSDSSDSSDSNESSDSSDSSDSSDSSNSSDSSDSSDSSDSTSDSNDESDSQSKSGNGNNN 1281
Query: 1997 ARSSAGERHGSHHQLQSAD 2015
S + GS ++D
Sbjct: 1282 GSDSDSDSEGSDSNHSTSD 1300
Score = 253 bits (646), Expect = 3e-66
Identities = 304/1371 (22%), Positives = 501/1371 (36%), Gaps = 115/1371 (8%)
Query: 377 RSSPGERH--GSGHQQSADSSRHSATGRGQASSAVSDRG---HRGSSGSQASDSEGHSEN 431
+S P ERH S + S S AS + + G H G G Q + +GH
Sbjct: 20 QSKPLERHVEKSMNLHLLARSNVSVQDELNASGTIKESGVLVHEGDRGRQENTQDGHKG- 78
Query: 432 SDTQSVSGHGKAGLRQQSHQESTRGRSGERSGRSGSSLYQVSTHE-QPDSAHGRTGTS-T 489
E + E G+S S+ ++ E + +G TG + T
Sbjct: 79 --------------------EGNGSKWAEVGGKSFSTYSTLANEEGNIEGWNGDTGKAET 118
Query: 490 GGRQGSHHEQARDSSRHSASQEGQDTIRGHPGSSRGGRQGSHHEQSVNRSGHSGSHHSHT 549
G G H ++ ++ +GQ +I + G++ + +++ + H+
Sbjct: 119 YGHDGIHGKEENITAN---GIQGQVSIIDNAGATNRSNTNGNTDKNTQNGDVGDAGHNED 175
Query: 550 TSQGRSDASHGQSGSRSASRQTRNEEQSGDGTRHSGSRHHEASSQADSSRHSQV--GQGQ 607
+ + D + S + E S ++ + +S+ + ++ ++V G G+
Sbjct: 176 VAVVQEDGPQVAGSNNSTDNEDEIIENSCRNEGNTSEITPQINSKRNGTKEAEVTPGTGE 235
Query: 608 SSGPRTSRNQGSSVSQDSDSQ---GHSEDSERWSGSASRNHHGSAQEQSRDGSRHPRSHH 664
+G S S D D G ED E +G S N+ + ++G H +
Sbjct: 236 DAGLDNSDGSPSGNGADEDEDEGSGDDEDEEAGNGKDSSNN-----SKGQEGQDHGKEDD 290
Query: 665 EDRAGHGHSADSSR---KSGTRHTQNSSSGQAASSHEQARSSAGERHGSRHQLQSADSSR 721
D + G ++DS G N G S E+ + E +GS+ +++
Sbjct: 291 HD-SSIGQNSDSKEYYDPEGKEDPHNEVDGDKTSKSEENSAGIPEDNGSQ-RIEDTQKLN 348
Query: 722 HSGTGHGQASSAVRDSGHRGSSGSQATDSEGHSEDSDTQSVSGHGQAGHHQQSHQESARD 781
H + S V + + S T + G S+D + + G + ++ +E +
Sbjct: 349 H------RESKRVENRITKESE----THAVGKSQD---KGIEIKGPSSGNRNITKEVGKG 395
Query: 782 RSGERSRRSGSFLYQVSTHKQSESSHGWTGPSTGVRQGSHHEQARDNSRHSASQDGQDTI 841
G+ + + K GP G + ++ N+ ++ DG D+
Sbjct: 396 NEGKEDKGQHGMILGKGNVKTQGEVVNIEGP--GQKSEPGNKVGHSNTGSDSNSDGYDSY 453
Query: 842 RGHPGSSRRGRQGSHHEQSVDRSGHSGSH-HSHTTSQGRSDASRGQ-----SGSRSASRT 895
+ QG S + +G+ ++ S S R DAS +G+ S S+
Sbjct: 454 ----DFDDKSMQGDDPNSSDESNGNDDANSESDNNSSSRGDASYNSDESKDNGNGSDSKG 509
Query: 896 TRNEEQSRDGSRHSGSRHHEASSHADISRHSQAGQGQSEGSRTSRRQGSSVSQDSDS-EG 954
+++ ++ + ++ D + S +G+G+S+ S + S+ S SDS +
Sbjct: 510 AEDDDSDSTSDTNNSDSNGNGNNGNDDNDKSDSGKGKSDSSDSDSSDSSNSSDSSDSSDS 569
Query: 955 HSEDSERWSGSASRNHRGSAQEQSRHGSRHPRSHHEDRAGHGHSADSSRQSGTPHAETSS 1014
S DS S S S + S S S D + S+DSS S + SS
Sbjct: 570 DSSDSNSSSDSDSSDSDSSDSSDSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSK--SDSS 627
Query: 1015 GGQAASSHEQARSSPGERHGSRHQQSADSSRHSGIPRRQASSAVRDSGHWGSSGSQASDS 1074
++ SS ++S + + S ++DSS S SS DS S S +SDS
Sbjct: 628 KSESDSSDSDSKSDSSDSNSSDSSDNSDSSDSSNSSNSSDSSDSSDS----SDSSSSSDS 683
Query: 1075 EGHSEESDTQSVSGHGQDGPHQQSHQESARDWSGGRSGRSGSFIYQVSTHEQSESAHGRT 1134
S+ SD+ S + S + D S + S S+S +
Sbjct: 684 SNSSDSSDSSDSSNSSESSDSSDSSDSDSSDSSDSSNSNS------------SDSDSSNS 731
Query: 1135 RTSTGRRQGSHHEQARDSSRHSASQEGQDTIRAHPGSRRGGRQGSHHEQSVDRSGHSGSH 1194
S+ S + DSS S S + D+ + S S S D S S S+
Sbjct: 732 SDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSNSSDSS-----DSSDSSDSSDSSNSSDSN 786
Query: 1195 HSHTTSQGRSDASHGQSGSRSASRQTRKDKQSGDGSRHSGSRHHEAASWADSSRHSQVGQ 1254
S +S SD+S+ S S+ D D S S S + +S + +S S
Sbjct: 787 DSSNSSDS-SDSSNSSDSSNSSDSSDSSDSSDSDSSNSSDSSNSSDSSDSSNSSDSSDSS 845
Query: 1255 EQSSGSRTSRHQGSSVSQDSDSERHSDDSERLSGSASRNHHGSSREQSRDGSRHPGFHQE 1314
+ S GS + S S SDS SD S S S + + SS S +
Sbjct: 846 DSSDGSDSDSSNRSDSSNSSDSSDSSDSSNSSDSSDSSDSNESSNSSDSSDSSN------ 899
Query: 1315 DRASHGHSADSSRQSGTHHTESSSHGQAVSSHEQARSSPGERHGSRHQQSADSSRHSGIG 1374
+S S+DSS S + + +SS S+ +S + S S+DSS S
Sbjct: 900 --SSDSDSSDSSNSSDSSDSSNSSDSSESSNSSDNSNSSDSSNSSDSSDSSDSSNSSDSS 957
Query: 1375 HRQASSAVRDSGHRGSSGSQVTNSEGHSEDSDTQSVSAHGQAGPHQQSHKESARGQSGES 1434
+ SS DS SS S ++S S+ SD+ S + S S S +S
Sbjct: 958 NSSDSSNSSDSSDSNSSDS--SDSSNSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDS 1015
Query: 1435 SGRSRSFLYQVSSHEQSESTHGQTAPSTGGRQGSRHEQARNSSRHSASQDGQDTIRGHPG 1494
S S S SS+ S ++ S+ S + NSS S S D D+
Sbjct: 1016 SNSSDSSNSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDS-----S 1070
Query: 1495 SSRGGRQGSYHEQSVDRSGHSGYHHSHTTPQGRSDASHGQSGPRSASRQTRNEEQSGDGS 1554
S S +S D S S S + + S S S + N S D S
Sbjct: 1071 DSSDSSDSSDSSESSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSS 1130
Query: 1555 RHSGSRHHEPSTRAGSSRHSQVGQGESAGSKTSRRQGSSVSQDRDSEGHSEDSERRSESA 1614
S S S+ + S S S S +S SS S D +S DS S+S+
Sbjct: 1131 DSSDSSDSSNSSDSSDSSESSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSS 1190
Query: 1615 SRNHYGSAREQSRHGSRNPRSHQEDRASHGHSAESSRQSGTRHAETSS----GGQAASSQ 1670
+ + + S + S D + S++SS S + + SS +++S
Sbjct: 1191 DSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSNESSDSSDSSDSSDSSNSS 1250
Query: 1671 EQARSSPGERHGSRHQQSADSSTDSGTGRRQDSSVVGDSGNRGSSGSQASD 1721
+ + SS S +DS + SG G S DS S+ S + D
Sbjct: 1251 DSSDSSDSSDSTSDSNDESDSQSKSGNGNNNGSDSDSDSEGSDSNHSTSDD 1301
Score = 252 bits (644), Expect = 5e-66
Identities = 310/1327 (23%), Positives = 488/1327 (36%), Gaps = 109/1327 (8%)
Query: 1026 RSSPGERH--GSRHQQSADSSRHSGIPRRQASSAVRDSG---HWGSSGSQASDSEGHSEE 1080
+S P ERH S + S S AS +++SG H G G Q + +GH E
Sbjct: 20 QSKPLERHVEKSMNLHLLARSNVSVQDELNASGTIKESGVLVHEGDRGRQENTQDGHKGE 79
Query: 1081 ---SDTQSVSGHGQDGPHQQSHQESARDWSGGRSGRSGSFIYQ-VSTHEQSESAHG---- 1132
S V G +++E + G +G++ ++ + + E++ +A+G
Sbjct: 80 GNGSKWAEVGGKSFSTYSTLANEEGNIEGWNGDTGKAETYGHDGIHGKEENITANGIQGQ 139
Query: 1133 ------RTRTSTGRRQGSHHEQARDSSRHSASQEGQDTIRAHPGSRRGGRQGS--HHEQS 1184
T+ G+ + ++ A + G + G S + ++
Sbjct: 140 VSIIDNAGATNRSNTNGNTDKNTQNGDVGDAGHNEDVAVVQEDGPQVAGSNNSTDNEDEI 199
Query: 1185 VDRSGHSGSHHSHTTSQ------GRSDASHGQSGSRSASRQTRKDKQSGDGSRH-----S 1233
++ S + + S T Q G +A A SG+G+ S
Sbjct: 200 IENSCRNEGNTSEITPQINSKRNGTKEAEVTPGTGEDAGLDNSDGSPSGNGADEDEDEGS 259
Query: 1234 GSRHHEAASWADSSRHSQVGQEQSSGSRTSRHQGSSVSQDSDSERHSDDS--ERLSGSAS 1291
G E A S ++ GQE + H SS+ Q+SDS+ + D E
Sbjct: 260 GDDEDEEAGNGKDSSNNSKGQEGQDHGKEDDHD-SSIGQNSDSKEYYDPEGKEDPHNEVD 318
Query: 1292 RNHHGSSREQSRDGSRHPGFHQEDRASHGHSADSSRQSGTHHTESSSHGQAVSSH---EQ 1348
+ S E S G + + + +S R ES +H S E
Sbjct: 319 GDKTSKSEENSAGIPEDNGSQRIEDTQKLNHRESKRVENRITKESETHAVGKSQDKGIEI 378
Query: 1349 ARSSPGERH-----GSRHQQSADSSRHS---GIGHRQASSAV---RDSGHRGSSGSQV-- 1395
S G R+ G ++ D +H G G+ + V G + G++V
Sbjct: 379 KGPSSGNRNITKEVGKGNEGKEDKGQHGMILGKGNVKTQGEVVNIEGPGQKSEPGNKVGH 438
Query: 1396 --TNSEGHSEDSDTQSVSAHGQAGPHQQSHKESARGQSGESSGRSRSFLYQVSSHEQSES 1453
T S+ +S+ D+ G S ES S + S +S+ ES
Sbjct: 439 SNTGSDSNSDGYDSYDFDDKSMQGDDPNSSDESNGNDDANSESDNNSSSRGDASYNSDES 498
Query: 1454 THGQTAPSTGGRQGSRHEQARNSSRHSASQDGQDTIRGHPGSSRG-GRQGSYHEQSVDRS 1512
+ G + + +++ ++ +G + + S G G+ S S D S
Sbjct: 499 KDNGNGSDSKGAEDDDSDSTSDTNNSDSNGNGNNGNDDNDKSDSGKGKSDSSDSDSSDSS 558
Query: 1513 GHSGYHHSHTTPQGRSDASHGQSGPRSASRQTRNEEQSGDGSRHSGSRHHEPSTRAGSSR 1572
S S + S++S S S + ++ S D S S S + S + SS
Sbjct: 559 NSSDSSDSSDSDSSDSNSSSDSDSSDSDSSDS-SDSDSSDSSNSSDSS--DSSDSSDSSD 615
Query: 1573 HSQVGQGESAGSKTSRRQGSSVSQDRDSEGHSEDSERRSESASRNHYGSAREQSRHGSRN 1632
S +S SK+ S S+ S+ +S DS S+S+ ++ ++ + S +
Sbjct: 616 SSDSSDSKSDSSKSESDSSDSDSKSDSSDSNSSDSSDNSDSSDSSNSSNSSDSSDSSDSS 675
Query: 1633 PRSHQEDRASHGHSAESSRQSGTRHAETSSGGQAASSQEQARSSPGERHGSRHQQSADSS 1692
S D ++ S++SS S + + SS + S + + SS S S+DSS
Sbjct: 676 DSSSSSDSSNSSDSSDSSDSSNSSESSDSSDSSDSDSSDSSDSSNSNSSDSDSSNSSDSS 735
Query: 1693 TDSGTGRRQDSSVVGDSGNRGSSGSQASDSEGHSEESDTQSVSAHGQAGPHQQSHQESTR 1752
S + DSS DS N S S +SDS S+ SD+ S + S+ S
Sbjct: 736 DSSNSSDSSDSS---DSSN-SSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSNDSSNS 791
Query: 1753 GQSGERSGRSGSFLYQVSTHEQSESAHGRTGPSTGGRQRSRHEQARDSSRHSASQEGQDT 1812
S + S S S ++ + S+S+ S+ S + DSS S S + D+
Sbjct: 792 SDSSDSSNSSDSS----NSSDSSDSSDSSDSDSSNSSDSSNSSDSSDSSNSSDSSDSSDS 847
Query: 1813 IRGHPGSSRGGRQGSHYEQSVDSSGHSGSHHSHTTSQER-----SDVSRGQSGSRSVSRQ 1867
G S S+ S DSS S S S +S SD S + S S S
Sbjct: 848 SDGSDSDSSNRSDSSNSSDSSDSSDSSNSSDSSDSSDSNESSNSSDSSDSSNSSDSDSSD 907
Query: 1868 TRNEKQSGDGSRHSGSRHHEASSRADSSRHSQVGQGQSSGPRTSRNQGSSVSQDSDSQGH 1927
+ N S D S S S E+S+ +D+S S S + + S S SDS
Sbjct: 908 SSNSSDSSDSSNSSDSS--ESSNSSDNSNSSDSSNSSDSSDSSDSSNSSDSSNSSDSSNS 965
Query: 1928 SEDSERWSGSASRNHLGSAWEQSRDGS----RHPGSHHEDRAGHGHSADSSRQSGTRHTE 1983
S+ S+ S +S + S S D S S+ D + S+DSS S + ++
Sbjct: 966 SDSSDSNSSDSSDSSNSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSNSSDSSNSS 1025
Query: 1984 SSSRGQAAS--SHEQARSSAGERHGSHHQLQSADSSRHSGIGHGQASSAVRDSGHRGYSG 2041
SS +S S S + + S S+DSS S SS DS S
Sbjct: 1026 DSSNSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSES- 1084
Query: 2042 SQASDSEGHSEDSDTQSVSAQGKAGPHQQSHKESARGQSGESSGRSGSFLYQVSTHEQSE 2101
S +SDS S+ SD+ S + S S S +SS S S
Sbjct: 1085 SDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDS------------ 1132
Query: 2102 STHGQSAPSTGGRQGSHYDQAQDSSRHSASQEGQDTIRGHPGPSRGGRQGSHQEQSVDRS 2161
S+ S+ S ++ DSS S S + D+ S S D S
Sbjct: 1133 ---SDSSDSSNSSDSSDSSESSDSSDSSDSSDSSDS--------------SDSSDSSDSS 1175
Query: 2162 GHSGSHHSHTTSQGRSDASRGQSGSRSASRKTYDKEQSGDGSRHSGSHHHEASSWADSSR 2221
S S S +S + S S S + D S D S S S SS ++ S
Sbjct: 1176 DSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSNESS 1235
Query: 2222 HSLVGQGQSSGPRTSRPRGSSVSQDSDSEGHSEDSERRSGSASRNHHGSAQEQSRDGSRH 2281
S S +S SS S DS S+ + E S+ +S S + N++GS + +GS
Sbjct: 1236 DSSDSSDSSDSSNSSDSSDSSDSSDSTSDSNDE-SDSQSKSGNGNNNGSDSDSDSEGSDS 1294
Query: 2282 PRSHHED 2288
S +D
Sbjct: 1295 NHSTSDD 1301
Score = 250 bits (638), Expect = 2e-65
Identities = 300/1297 (23%), Positives = 459/1297 (35%), Gaps = 101/1297 (7%)
Query: 1682 GSRHQQSADSSTDSGTGRRQDSSVVGDSGNRGSSGSQASDSEGHSE--ESDTQSVSAHGQ 1739
G R +Q G G + VG G S+ S ++ EG+ E DT +G
Sbjct: 64 GDRGRQENTQDGHKGEGNGSKWAEVG--GKSFSTYSTLANEEGNIEGWNGDTGKAETYGH 121
Query: 1740 AGPHQQSHQESTRGQSGE-----------RSGRSGSFLYQVSTHEQSESAHGRT------ 1782
G H + + G G+ RS +G+ + ++ H
Sbjct: 122 DGIHGKEENITANGIQGQVSIIDNAGATNRSNTNGNTDKNTQNGDVGDAGHNEDVAVVQE 181
Query: 1783 -GPSTGGRQRSRHEQARDSSRHSASQEGQDTIRGHPGSSRGGRQGSHYEQSVDSSGHSGS 1841
GP G S + + +S EG S ++S +G+
Sbjct: 182 DGPQVAGSNNSTDNED-EIIENSCRNEGNT---------------SEITPQINSK-RNGT 224
Query: 1842 HHSHTTSQERSDVSRGQSGSRSVSRQTRNEKQSGDGSRHSGSRHHEASSRADSSRHSQVG 1901
+ T D S ++ G G EA + DSS +S+
Sbjct: 225 KEAEVTPGTGEDAGLDNSDGSPSGNGADEDEDEGSGD----DEDEEAGNGKDSSNNSKGQ 280
Query: 1902 QGQSSGPRTSRNQGSSVSQDSDSQGHSEDSERWSGSASRNHLGSAWEQSRDGSRHPGSHH 1961
+GQ G + SS+ Q+SDS+ + + +G P H
Sbjct: 281 EGQDHGKEDDHD--SSIGQNSDSKEYYDP---------------------EGKEDP---H 314
Query: 1962 EDRAGHGHSADSSRQSGTRHTESSSRGQAASSHEQARSSAGE-RHGSHHQLQSADSSRHS 2020
+ G S +G S R + S E R + + S+
Sbjct: 315 NEVDGDKTSKSEENSAGIPEDNGSQRIEDTQKLNHRESKRVENRITKESETHAVGKSQDK 374
Query: 2021 GIGHGQASSAVRDSGHRGYSGSQASDSEG-HSEDSDTQSVSAQGKA----GPHQQSHKES 2075
GI SS R+ G++ + +G H +V QG+ GP Q+S +
Sbjct: 375 GIEIKGPSSGNRNITKEVGKGNEGKEDKGQHGMILGKGNVKTQGEVVNIEGPGQKSEPGN 434
Query: 2076 ARGQS--GESSGRSGSFLYQVSTHEQSESTHGQSAPSTGGRQGSHYDQAQDSSRHSASQE 2133
G S G S G Y S S G + SSR AS
Sbjct: 435 KVGHSNTGSDSNSDGYDSYDFDDKSMQGDDPNSSDESNGNDDANSESDNNSSSRGDASYN 494
Query: 2134 GQDTIRGHPGPSRGGRQGSHQEQSVD--RSGHSGSHHSHTTSQGRSDASRGQSGSRSASR 2191
++ G G + + + D S +G+ ++ +SD+ +G+S S +
Sbjct: 495 SDESKDNGNGSDSKGAEDDDSDSTSDTNNSDSNGNGNNGNDDNDKSDSGKGKSDSSDSDS 554
Query: 2192 KTYDKEQSGDGSRHSGSHHHEASSWADSSRHSLVGQGQSSGPRTSRPRGSSVSQD-SDSE 2250
S S S +SS +DSS S +S SS S D SDS
Sbjct: 555 SDSSNSSDSSDSSDSDSSDSNSSSDSDSSDSDSSDSSDSDSSDSSNSSDSSDSSDSSDSS 614
Query: 2251 GHSEDSERRSGSASRNHHGSAQEQSRDGSRHPRSHHEDRAGHGHSAESSRQSGTHHAENS 2310
S+ S+ +S S+ S + D S S D + S+ SS S + + +S
Sbjct: 615 DSSDSSDSKSDSSKSESDSSDSDSKSDSSDSNSSDSSDNSDSSDSSNSSNSSDSSDSSDS 674
Query: 2311 SGGQAASSHEQARSSAGERHGSHHQQSADSSRHSGIGHGQA--SSAVRDSGHRGSSGSQA 2368
S ++S + S+ S+ +S+DSS S + SS S S+ S +
Sbjct: 675 SDSSSSSDSSNSSDSSDSSDSSNSSESSDSSDSSDSDSSDSSDSSNSNSSDSDSSNSSDS 734
Query: 2369 SDSEGHSEDSDTQSVSAHGQAGPHQQSHQESTRGRSAGRSGRSGSFLYQVS-----THEQ 2423
SDS S+ SD+ S + S S S+ S S S S + +
Sbjct: 735 SDSSNSSDSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSNDSSNSSDS 794
Query: 2424 SESAHGRTGTSTGGRQGSHHKQARDSSRHSTSQEGQDTIHGHPGSSSGGRQGSHYEQLVD 2483
S+S++ +++ S DSS S S D+ S S S D
Sbjct: 795 SDSSNSSDSSNSSDSSDSSDSSDSDSSNSSDSSNSSDSSDSSNSSDSSDSSDSSDGSDSD 854
Query: 2484 RSGHSGSHHSHTTSQGRSDASHGHSGSRSASRQTRNDEQSGDGSRHSGSRHHEASSRADS 2543
S S S +S +S ++ S S S ++ N S D S S S ++S+ +DS
Sbjct: 855 SSNRSDSSNSSDSSDSSDSSNSSDSSDSSDSNESSNSSDSSDSSNSSDSDSSDSSNSSDS 914
Query: 2544 SGHSQVGQGQSEGPRTSRNWGSSFSQDSDSQGHSEDSERWSGSA----SRNHHGSAQEQL 2599
S S SE +S N SS S +S S DS S S+ S N S+
Sbjct: 915 SDSSN-SSDSSESSNSSDNSNSSDSSNSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSNS 973
Query: 2600 RDGSRHPRSHQEDRAGHGHSADSSRQSGTRHTQTSSGGQAASSHEQARSSAGERHGSHHQ 2659
D S S+ D + S+DSS S + ++ SS +S + S+ S+
Sbjct: 974 SDSS--DSSNSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSNSSDSSNSSDSSNSS 1031
Query: 2660 QSADSSRHSGIGHGQASSAVRDSGHRGYSGSQASDNEGHSEDSDTQSVSAHGQAGSHQQS 2719
S+DSS S SS DS + S S +SD+ S+ SD+ S ++ S
Sbjct: 1032 DSSDSSDSSDSSDSSDSSDSSDSSNSSDS-SDSSDSSDSSDSSDSSDSSDSSESSDSSDS 1090
Query: 2720 HQESARGRSGETSGHSGSFLYQVSTHEQSESSHGWTGPSTRGRQGSRHEQAQDSSRHSAS 2779
S S ++S S S S+ S+ + S+ S + DSS S S
Sbjct: 1091 SNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSSDSSES 1150
Query: 2780 QDGQDTIRGHPGSSRGGRQGYHHEHSVDSSGHSGSHHSHTTSQGRSDASRGQSGSRSASR 2839
D D+ S S DSS S S S +S + S S S
Sbjct: 1151 SDSSDS-----SDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSS 1205
Query: 2840 TTRNEEQSGDGSRHSGSRHHEASTHADISRHSQAVQGQSEGSRRSRRQGSSVSQDSDSEG 2899
+ + S D S S S S+ ++ S S S+ S S SS S DS S+
Sbjct: 1206 DSSDSSDSSDSSDSSDSSDSSDSSDSNESSDSSDSSDSSDSSNSSDSSDSSDSSDSTSDS 1265
Query: 2900 HSEDSERWSGSASRNHHGSAQEQLRDGSRHPRSHQED 2936
+ E S+ S S + N++GS + +GS S +D
Sbjct: 1266 NDE-SDSQSKSGNGNNNGSDSDSDSEGSDSNHSTSDD 1301
Score = 246 bits (627), Expect = 4e-64
Identities = 291/1292 (22%), Positives = 465/1292 (35%), Gaps = 98/1292 (7%)
Query: 2027 ASSAVRDSG---HRGYSGSQASDSEGHSEDSDTQSVSAQGKAGPHQQSHKESARGQSGES 2083
AS +++SG H G G Q + +GH + + S + G S + + G
Sbjct: 50 ASGTIKESGVLVHEGDRGRQENTQDGHKGEGNG---SKWAEVGGKSFSTYSTLANEEGNI 106
Query: 2084 SGRSGSFLYQVSTHEQSESTHGQSAPSTGGRQGSHYDQAQDSSRHSASQEGQDTIRGHPG 2143
G +G T G G H ++ + + +GQ +I + G
Sbjct: 107 EGWNGD----------------TGKAETYGHDGIH---GKEENITANGIQGQVSIIDNAG 147
Query: 2144 PSRGGRQGSHQEQSVDRSGHSGSHHSHTTSQGRSDASRGQSGSRSASRKTYDKEQSGDGS 2203
+ + +++ + H+ + + D + + S + E S
Sbjct: 148 ATNRSNTNGNTDKNTQNGDVGDAGHNEDVAVVQEDGPQVAGSNNSTDNEDEIIENSCRNE 207
Query: 2204 RHSGSHHHEASSWADSSRHSLV--GQGQSSGPRTS--RPRGSSVSQDSDSEGHSEDSERR 2259
++ + +S + ++ + V G G+ +G S P G+ +D D EG +D +
Sbjct: 208 GNTSEITPQINSKRNGTKEAEVTPGTGEDAGLDNSDGSPSGNGADEDED-EGSGDDEDEE 266
Query: 2260 SGSASRNHHGSAQEQSRDGSRHPRSHHEDRAGHGHSAESSRQSGTHHAENSSGGQAASSH 2319
+G+ + + S ++ +D + H + S E G N G S
Sbjct: 267 AGNGKDSSNNSKGQEGQDHGKED-DHDSSIGQNSDSKEYYDPEGKEDPHNEVDGDKTSKS 325
Query: 2320 EQARSSAGERHGS---------HHQQS---------------ADSSRHSGIGHGQASSAV 2355
E+ + E +GS +H++S S+ GI SS
Sbjct: 326 EENSAGIPEDNGSQRIEDTQKLNHRESKRVENRITKESETHAVGKSQDKGIEIKGPSSGN 385
Query: 2356 RDSGHRGSSGSQASDSEG-HSEDSDTQSVSAHGQA----GPHQQSHQESTRGRS--AGRS 2408
R+ G++ + +G H +V G+ GP Q+S + G S S
Sbjct: 386 RNITKEVGKGNEGKEDKGQHGMILGKGNVKTQGEVVNIEGPGQKSEPGNKVGHSNTGSDS 445
Query: 2409 GRSGSFLYQVSTHEQSESAHGRTGTSTGGRQGSHHKQARDSSRHSTSQEGQDTIHGHPGS 2468
G Y + S G + SSR S ++ GS
Sbjct: 446 NSDGYDSYDFDDKSMQGDDPNSSDESNGNDDANSESDNNSSSRGDASYNSDESKDNGNGS 505
Query: 2469 SSGGRQGSHYEQLVD--RSGHSGSHHSHTTSQGRSDASHGHSGSRSASRQTRNDEQSGDG 2526
S G + + D S +G+ ++ +SD+ G S S + ++
Sbjct: 506 DSKGAEDDDSDSTSDTNNSDSNGNGNNGNDDNDKSDSGKGKSDSSDSDSSDSSNSSDSSD 565
Query: 2527 SRHSGSRHHEASSRADSSGHSQVGQGQSEGPRTSRNWGSSFSQDSDSQGHSEDSERWSGS 2586
S S S +SS +DSS S+ +S + SS S DS S DS
Sbjct: 566 SSDSDSSDSNSSSDSDSSDSDSSDSSDSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSKSD 625
Query: 2587 ASRNHHGSAQEQLRDGSRHPRSHQEDRAGHGHSADSSRQSGTRHTQTSSGGQAASSHEQA 2646
+S++ S+ + S S+ D + + S+DSS S + + SS +SS +
Sbjct: 626 SSKSESDSSDSDSKSDSSD--SNSSDSSDNSDSSDSSNSSNSSDSSDSSDSSDSSSSSDS 683
Query: 2647 RSSAGERHGSHHQQSADSSRHSGIGHGQASSAVRDSGHRGYSGSQASDNEGHSEDSDTQS 2706
+S+ S S++SS S +S DS S S SD+ S+ SD+ +
Sbjct: 684 SNSSDSSDSSDSSNSSESSDSSDSSDSDSS----DSSDSSNSNSSDSDSSNSSDSSDSSN 739
Query: 2707 VSAHGQAGSHQQSHQESARGRSGETSGHSGSFLYQVSTHEQSESSHGWTGPSTRGRQGSR 2766
S + S S S +S S S S+ + S + S+ S
Sbjct: 740 SSDSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSNDSSNSSDSSDSSN 799
Query: 2767 HEQAQDSSRHSASQDGQDTIRGHPGSSRGGRQGYHHEHSVDSSGHS-GSHHSHTTSQGRS 2825
+ +SS S S D D+ + S +S DSS S S S + S RS
Sbjct: 800 SSDSSNSSDSSDSSDSSDSDSSNSSDSSNSSDSSDSSNSSDSSDSSDSSDGSDSDSSNRS 859
Query: 2826 DASRGQSGSRSA-------------SRTTRNEEQSGDGSRHSGSRHHEASTHADISRHSQ 2872
D+S S S+ S + N S D S S S ++S +D S S
Sbjct: 860 DSSNSSDSSDSSDSSNSSDSSDSSDSNESSNSSDSSDSSNSSDSDSSDSSNSSDSSDSSN 919
Query: 2873 AVQGQSEGSRRSRRQGSSVSQDSDSEGHSEDSERWSGSA----SRNHHGSAQEQLRDGSR 2928
+ SE S S SS S +S S DS S S+ S N S+ D S
Sbjct: 920 S-SDSSESSNSSDNSNSSDSSNSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSNSSDSS- 977
Query: 2929 HPRSHQEDRAGHGHSADSSRQSGTRHTQTSSGGQAASSHEQARSSAGERHGSHHQQSADS 2988
S+ D + S+DSS S + ++ SS +S + S+ S+ S+DS
Sbjct: 978 -DSSNSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDS 1036
Query: 2989 SRHSGIGHGQASSAVRDSGHRGYSGSQASDNEGHSEDSDTQSVSAHGQAGSHQQSHQESA 3048
S S SS DS + S S +SD+ S+ SD+ S ++ S S
Sbjct: 1037 SDSSDSSDSSDSSDSSDSSNSSDS-SDSSDSSDSSDSSDSSDSSDSSESSDSSDSSNSSD 1095
Query: 3049 RGRSGETSGHSGSFLYQVSTHEQSESSHGWTGPSTRGRQGSRHEQAQDSSRHSASQYGQD 3108
S ++S S S S+ S+ + S+ S + DSS S S D
Sbjct: 1096 SSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSSDSSESSDSSD 1155
Query: 3109 TIRGHPGSSRGGRQGYHHEHSVDSSGHSGSHHSHTTSQGRSDASRGQSGSRSASRTTRNE 3168
+ S S DSS S S S +S + S S S + +
Sbjct: 1156 S-----SDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDS 1210
Query: 3169 EQSGDSSRHSVSRHHEASTHADISRHSQAVQGQSEGSRRSRRQGSSVSQDSDSEGHSEDS 3228
S DSS S S S+ ++ S S S+ S S SS S DS S+ + E S
Sbjct: 1211 SDSSDSSDSSDSSDSSDSSDSNESSDSSDSSDSSDSSNSSDSSDSSDSSDSTSDSNDE-S 1269
Query: 3229 ERWSGSASRNHRGSVQEQSRHGSRHPRSHHED 3260
+ S S + N+ GS + GS S +D
Sbjct: 1270 DSQSKSGNGNNNGSDSDSDSEGSDSNHSTSDD 1301
Score = 239 bits (611), Expect = 3e-62
Identities = 255/1054 (24%), Positives = 405/1054 (38%), Gaps = 71/1054 (6%)
Query: 98 GHKHRKHSHHD----KHEDNKQEENKENRKRP-SSLERRNNRKGNKGRSKSPRETGGKRH 152
G H K HD ++ D+K+ + E ++ P + ++ K + + P + G +R
Sbjct: 282 GQDHGKEDDHDSSIGQNSDSKEYYDPEGKEDPHNEVDGDKTSKSEENSAGIPEDNGSQRI 341
Query: 153 ESSSEKKERKGYSPTHREEEYGKNHHNSSKKEKNKTENTRLGDNR---KRLSERLEEKED 209
E + + R+ +R + + H ++K NR K + + E KED
Sbjct: 342 EDTQKLNHRESKRVENRITKESETHAVGKSQDKGIEIKGPSSGNRNITKEVGKGNEGKED 401
Query: 210 NEEG--------------VYDYENTGRMTQKWIQSGHIATYYTIQDEAYDTTD----SLL 251
+ V + E G+ ++ + GH T + YD+ D S+
Sbjct: 402 KGQHGMILGKGNVKTQGEVVNIEGPGQKSEPGNKVGHSNTGSDSNSDGYDSYDFDDKSMQ 461
Query: 252 --EENKIYERSRSSDGKSSSQVNRSRHENTSQVPLQESRTRKRRGSRVSQDRDSEGHSED 309
+ N E + + D S S N S + S + S+ ++D DS+ S D
Sbjct: 462 GDDPNSSDESNGNDDANSESDNNSSSRGDASYNSDESKDNGNGSDSKGAEDDDSDSTS-D 520
Query: 310 SERHSGSASRNHHGSAWEQSRDGSRHPRSHDEDRASHGHSADSSRQSGTRHAETSSRGQT 369
+ + + N+ ++S G S D D + +S+DSS S + ++++S +
Sbjct: 521 TNNSDSNGNGNNGNDDNDKSDSGKGKSDSSDSDSSDSSNSSDSSDSSDSDSSDSNSSSDS 580
Query: 370 ASSHEQARSSPGERHGSGHQQSADSSRHSATGRGQASSAVSDRGHRGSSGSQASDSEGHS 429
SS + S S+DSS S + SS SD S +SDS+ S
Sbjct: 581 DSSDSDSSDS-------SDSDSSDSSNSSDSSDSSDSSDSSD-------SSDSSDSKSDS 626
Query: 430 ENSDTQSVSGHGKAGLRQQSHQESTRGRSGERSGRSGSSLYQVSTHEQPDSAHGRTGTST 489
S++ S K+ +S S + S S SS S+ S + +S+
Sbjct: 627 SKSESDSSDSDSKS-----DSSDSNSSDSSDNSDSSDSSNSSNSSDSSDSSDSSDSSSSS 681
Query: 490 GGRQGSHHEQARDSSRHSASQEGQDTIRGHPG-SSRGGRQGSHHEQSVNRSGHSGSHHSH 548
S + DSS S S + D+ SS S S N S S S +S
Sbjct: 682 DSSNSSDSSDSSDSSNSSESSDSSDSSDSDSSDSSDSSNSNSSDSDSSNSSDSSDSSNSS 741
Query: 549 TTSQGRSDASHGQSGSRSASRQTRNEEQSGDGTRHSGSRHHEASSQADSSRHSQVGQGQS 608
+S ++ S S S + + S D + S S + S+ + +S S S
Sbjct: 742 DSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSNDSSNSSDSSDSSNSS 801
Query: 609 SGPRTSRNQGSSVSQDSDSQGHSEDSERWSGSASRNHHGSA-QEQSRDGSRHPRSHHEDR 667
+S + SS S DSDS S+ S S S N S+ S DGS S+ D
Sbjct: 802 DSSNSSDSSDSSDSSDSDSSNSSDSSNSSDSSDSSNSSDSSDSSDSSDGSDSDSSNRSDS 861
Query: 668 AGHGHSADSSRKSGTRHTQNSS-SGQAASSHEQARSSAGERHGSRHQLQSADSSRHSGTG 726
+ S+DSS S + + +SS S ++++S + + SS S S+DSS S +
Sbjct: 862 SNSSDSSDSSDSSNSSDSSDSSDSNESSNSSDSSDSSNSSDSDSSDSSNSSDSSDSSNSS 921
Query: 727 HGQASSAVRDSGHR--GSSGSQATDSEGHSEDSDTQSVSGHGQAGHHQQSHQESARD--R 782
SS D+ + S+ S ++DS S SD+ + S + S+ + D
Sbjct: 922 DSSESSNSSDNSNSSDSSNSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSNSSDSSDSSN 981
Query: 783 SGERSRRSGSFLYQVSTHKQSESSHGWTGPSTGVRQGSHHEQARDNSRHSASQDGQDTIR 842
S + S S S S+ + S + S+ S + D+S S S D D+
Sbjct: 982 SSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSSDS-- 1039
Query: 843 GHPGSSRRGRQGSHHEQSVDRSGHSGSHHSHTTSQGRSDASRGQSGSRSASRTTRNEEQS 902
S S S D S S S S +S + +S S S + + S
Sbjct: 1040 SDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSESSDSSDSSNSSDSSDS 1099
Query: 903 RDGSRHSGSRHHEASSHADISRHSQAGQGQSEGSRTSRRQGSSVSQDSDSEGHSEDSERW 962
D S S S SS + S +S S+ S +S SS S DS S DS
Sbjct: 1100 SDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSSDSSESSDSSDSSDS 1159
Query: 963 SGSASRNHRGSAQEQSRHGSRHPRSHHEDRAGHGHSADSSRQSGTPHAETSSGGQAASSH 1022
S S+ + + + S + S D + S+DSS S + + SS +S
Sbjct: 1160 SDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDS 1219
Query: 1023 EQARSSPGERHGSRHQQSADSSRHSGIPRRQASSAVRDSGHWGSSGSQASDSEGHSEESD 1082
+ S + S+DSS S SS DS S SDS ++ESD
Sbjct: 1220 SDSSDSSDSSDSNESSDSSDSSDSSD------SSNSSDSSDSSDSSDSTSDS---NDESD 1270
Query: 1083 TQSVSGHGQDGPHQQSHQESARDWSGGRSGRSGS 1116
+QS SG+G + + +S D G S S S
Sbjct: 1271 SQSKSGNGNN-----NGSDSDSDSEGSDSNHSTS 1299
Score = 237 bits (604), Expect = 2e-61
Identities = 298/1357 (21%), Positives = 471/1357 (34%), Gaps = 90/1357 (6%)
Query: 166 PTHREEEYGKNHHNSSKKEKNKTENTRLGDNRKRLSERLEE----KEDNEEGVYDYENTG 221
P R E N H ++ + + K + E +++N + + E G
Sbjct: 23 PLERHVEKSMNLHLLARSNVSVQDELNASGTIKESGVLVHEGDRGRQENTQDGHKGEGNG 82
Query: 222 RMTQKWIQSG--HIATYYTIQDEAYDTTDSLLEENKIYERSRSSDGKSSSQVNRSRHENT 279
KW + G +TY T+ +E + + K + DG + N + +
Sbjct: 83 ---SKWAEVGGKSFSTYSTLANEEGNIEGWNGDTGKA--ETYGHDGIHGKEENITANGIQ 137
Query: 280 SQVPLQESRTRKRRGSRVSQDRDSEGHSEDSERHSGSASRNHHGSAWEQSRDGSRHPRSH 339
QV + ++ R + + G+++ + ++ H+ DG + S+
Sbjct: 138 GQVSIIDNAGATNRSN-------TNGNTDKNTQNGDVGDAGHNEDVAVVQEDGPQVAGSN 190
Query: 340 DEDRASHGHSADSSRQSGTRHAETSSRGQTASSHEQARSSPGERHGSGHQQSADSSRHSA 399
+ +S R G T + ++A +PG +G D+S S
Sbjct: 191 NSTDNEDEIIENSCRNEGNTSEITPQINSKRNGTKEAEVTPG----TGEDAGLDNSDGSP 246
Query: 400 TGRGQASSAVSDRGHRGSSGSQASDSEGHSENSDTQSVSGHGKAGLRQQSHQESTRGRSG 459
+G G D G +A + + S NS Q HGK + H S S
Sbjct: 247 SGNGADED--EDEGSGDDEDEEAGNGKDSSNNSKGQEGQDHGK----EDDHDSSIGQNSD 300
Query: 460 ERSGRSGSSLYQVSTHEQPDSAHGRTGTSTGGRQGSHHEQARDSSRHSASQEGQDTIRGH 519
+ + P+ G++ H+E D + S S+E I
Sbjct: 301 SKE------------YYDPE-----------GKEDPHNEV--DGDKTSKSEENSAGIPED 335
Query: 520 PGSSR-GGRQGSHHEQSVNRSGHSGSHHSHTTSQGRS-DASHGQSGSRSASRQTRNEEQS 577
GS R Q +H +S R + + S T + G+S D G S +R E
Sbjct: 336 NGSQRIEDTQKLNHRES-KRVENRITKESETHAVGKSQDKGIEIKGPSSGNRNITKEVGK 394
Query: 578 GDGTRHSGSRHHEASSQADSSRHSQV----GQGQSSGPRTSRNQGSSVSQDSDSQGHSED 633
G+ + +H + + +V G GQ S P S+ DS+S G+ D
Sbjct: 395 GNEGKEDKGQHGMILGKGNVKTQGEVVNIEGPGQKSEPGNKVGH-SNTGSDSNSDGY--D 451
Query: 634 SERWSGSASRNHHGSAQEQSRDGSRHPRSHHEDRAGHGHSADSSRKSGTRHTQNSSSGQA 693
S + ++S G P S E +++S S +R + +S ++
Sbjct: 452 SYDFD------------DKSMQGD-DPNSSDESNGNDDANSESDNNSSSRGDASYNSDES 498
Query: 694 ASSHEQARSSAGERHGSRHQLQSADSSRHSGTGHGQASSAVRDSGHRGSSGSQATDSEGH 753
+ + S E S + +S + +G + DSG +G S S +DS
Sbjct: 499 KDNGNGSDSKGAEDDDSDSTSDTNNSDSNGNGNNGNDDNDKSDSG-KGKSDSSDSDSSDS 557
Query: 754 SEDSDTQSVSGHGQAGHHQQSHQESARDRSGERSRRSGSFLYQVSTHKQSESSHGWTGPS 813
S SD+ S + + S +S+ S + S S + S+SS + S
Sbjct: 558 SNSSDSSDSSDSDSSDSNSSSDSDSSDSDSSDSSDSDSS-----DSSNSSDSSD--SSDS 610
Query: 814 TGVRQGSHHEQARDNSRHSASQDGQDTIRGHPGSSRRGRQGSHHEQSVDRSGHSGSHHSH 873
+ S ++ +S S S D D+ S S + S D S S S S
Sbjct: 611 SDSSDSSDSSDSKSDSSKSES-DSSDSDSKSDSSDSNSSDSSDNSDSSDSSNSSNSSDSS 669
Query: 874 TTSQGRSDASRGQSGSRSASRTTRNEEQSRDGSRHSGSRHHEASSHADISRHSQAGQGQS 933
+S +S S + S S + + S + S S S ++S +D S + + S
Sbjct: 670 DSSDSSDSSSSSDSSNSSDSSDSSDSSNSSESSDSSDSSDSDSSDSSDSSNSNSSDSDSS 729
Query: 934 EGSRTSRRQGSSVSQDSDSEGHSEDSERWSGSASRNHRGSAQEQSRHGSRHPRSHHEDRA 993
S +S SS S DS +S DS S S++ + + + S S D +
Sbjct: 730 NSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSNDSS 789
Query: 994 GHGHSADSSRQSGTPHAETSSGGQAASSHEQARSSPGERHGSRHQQSADSSRHSGIPRRQ 1053
S+DSS S + ++ SS +S + + SS S S+DSS S
Sbjct: 790 NSSDSSDSSNSSDSSNSSDSSDSSDSSDSDSSNSS----DSSNSSDSSDSSNSSDSSDSS 845
Query: 1054 ASSAVRDSGHWGSSGSQASDSEGHSEESDTQSVSGHGQDGPHQQSHQESARDWSGGRSGR 1113
SS DS S S S S +S S S D + +S+ + S
Sbjct: 846 DSSDGSDSDSSNRSDSSNSSDSSDSSDSSNSSDSSDSSDSNESSNSSDSSDSSNSSDSDS 905
Query: 1114 SGSFIYQVSTHEQSESAHGRTRTSTGRRQGSHHEQARDSSRHSASQEGQDTIRAHPGSRR 1173
S S S+ + S + S+ S + DSS S S D+ + S
Sbjct: 906 SDSSNSSDSSDSSNSSDSSESSNSSDNSNSSDSSNSSDSSDSSDSSNSSDSSNSSDSSNS 965
Query: 1174 GGRQGSHHEQSVDRSGHSGSHHSHTTSQGRSDASHGQSGSRSASRQTRKDKQSGDGSRHS 1233
S+ S D S S S S +S + S S S + S D S S
Sbjct: 966 SDSSDSNSSDSSDSSNSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSNSSDSSNSS 1025
Query: 1234 GSRHHEAASWADSSRHSQVGQEQSSGSRTSRHQGSSVSQDSDSERHSDDSERLSGSASRN 1293
S + +S + S S + S S +S SS S DS S DS S S+ +
Sbjct: 1026 DSSNSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSESS 1085
Query: 1294 HHGSSREQSRDGSRHPGFHQEDRASHGHSADSSRQSGTHHTESSSHGQAVSSHEQARSSP 1353
S S D + S+DSS S + + SS S + S
Sbjct: 1086 DSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSS 1145
Query: 1354 GERHGSRHQQSADSSRHSGIGHRQASSAVRDSGHRGSSGSQVTNSEGHSEDSDTQSVSAH 1413
S S+DSS S SS DS + S S ++S S+ SD+ S
Sbjct: 1146 DSSESSDSSDSSDSSDSSDSSDSSDSSDSSDSSN-SSDSSDSSDSSDSSDSSDSSDSSDS 1204
Query: 1414 GQAGPHQQSHKESARGQSGESSGRSRSFLYQVSSHEQSESTHGQTAPSTGGRQGSRHEQA 1473
+ S S S +SS S S SS S ++ S+ S
Sbjct: 1205 SDSSDSSDSSDSSDSSDSSDSSDSSDSNESSDSSDSSDSSDSSNSSDSSDSSDSSDSTSD 1264
Query: 1474 RNSSRHSASQDGQDTIRGHPGSSRGGRQGSYHEQSVD 1510
N S S+ G G S S H S D
Sbjct: 1265 SNDESDSQSKSGNGNNNGSDSDSDSEGSDSNHSTSDD 1301
Score = 237 bits (604), Expect = 2e-61
Identities = 291/1327 (21%), Positives = 473/1327 (35%), Gaps = 107/1327 (8%)
Query: 2220 SRHSLVGQGQSSGPRTSRPRGSSVSQ-DSDSEGHSEDSERRSGSASR-NHHGSAQEQSRD 2277
+R ++ Q + + T + G V + D + +++D + G+ S+ G +
Sbjct: 38 ARSNVSVQDELNASGTIKESGVLVHEGDRGRQENTQDGHKGEGNGSKWAEVGGKSFSTYS 97
Query: 2278 GSRHPRSHHEDRAGHGHSAESSRQSGTHHAENSSGGQAASSHEQARSSAGERHGSHHQQS 2337
+ + E G AE+ G H E + +AG + S+ +
Sbjct: 98 TLANEEGNIEGWNGDTGKAETYGHDGIHGKEENITANGIQGQVSIIDNAGATNRSNTNGN 157
Query: 2338 ADSSRHSG----IGHGQASSAVRDSGHRGSSGSQASDSEGHSEDSDTQSVSAHGQAGPHQ 2393
D + +G GH + + V++ G + + + ++D+E ++ ++ + P
Sbjct: 158 TDKNTQNGDVGDAGHNEDVAVVQEDGPQVAGSNNSTDNEDEIIENSCRNEGNTSEITPQI 217
Query: 2394 QSHQESTR--------GRSAGRSGRSGSFLYQVSTHEQSESAHGRTGTSTGGRQGSHHKQ 2445
S + T+ G AG GS + ++ E + G +
Sbjct: 218 NSKRNGTKEAEVTPGTGEDAGLDNSDGSPSGNGADEDEDEGS--------GDDEDEEAGN 269
Query: 2446 ARDSSRHSTSQEGQDTIHGHPGSSSGGRQGSHYEQLVDRSGHSGSHHSHTTSQGRSDASH 2505
+DSS +S QEGQD SS G Q S ++ D G H+ + +
Sbjct: 270 GKDSSNNSKGQEGQDHGKEDDHDSSIG-QNSDSKEYYDPEGKEDPHNEVDGDKTSKSEEN 328
Query: 2506 GHSGSRSASRQTRNDEQSGDGSRHSGSRHHEASSRADSSGHSQVGQGQSEGPRTSRNWGS 2565
Q D Q H S+ E +S H+ VG+ Q +G G
Sbjct: 329 SAGIPEDNGSQRIEDTQK---LNHRESKRVENRITKESETHA-VGKSQDKGIEIK---GP 381
Query: 2566 SFSQDSDSQGHSEDSERWSGSASRNHHGSAQEQLRDGSRHPRSHQEDRAGHGHSADSSRQ 2625
S + ++ + +E G + HG L G+ + + G G ++ +
Sbjct: 382 SSGNRNITKEVGKGNE---GKEDKGQHGMI---LGKGNVKTQGEVVNIEGPGQKSEPGNK 435
Query: 2626 SGTRHTQTSSGGQAASSHE--------QARSSAGERHGSHHQQSADSSRHSGIGHGQASS 2677
G +T + S S++ +S+ E +G+ S + S G +S
Sbjct: 436 VGHSNTGSDSNSDGYDSYDFDDKSMQGDDPNSSDESNGNDDANSESDNNSSSRGDASYNS 495
Query: 2678 -AVRDSGHRGYSGSQASDNEGHSEDSDTQSVSAHGQAGSHQQSHQESARGRSGETSGHSG 2736
+D+G+ S D+ + D++ + +G G+ +S +G+S + S
Sbjct: 496 DESKDNGNGSDSKGAEDDDSDSTSDTNNSDSNGNGNNGNDDNDKSDSGKGKSDSSDSDSS 555
Query: 2737 SFLYQVSTHEQSESSHGWTGPSTRGRQGSRHEQAQDSSRHSASQDGQDTIRGHPGSSRGG 2796
+ S+SS S+ S + + S S+ D D+ S
Sbjct: 556 D------SSNSSDSSDSSDSDSSDSNSSSDSDSSDSDSSDSSDSDSSDSSNSSDSS---- 605
Query: 2797 RQGYHHEHSVDSSGHSGSHHSHTTSQGRSDASRGQSGSR-SASRTTRNEEQSGDGSRHSG 2855
DSS S S S +S +SD+S+ +S S S S++ ++ S D S +S
Sbjct: 606 ----------DSSDSSDSSDSSDSSDSKSDSSKSESDSSDSDSKSDSSDSNSSDSSDNSD 655
Query: 2856 SRHHEASTHADISRHSQAVQGQSEGSRRSRRQGSSVSQDSDSEGHSEDSERWSGSASRNH 2915
S S+++ S S S S S SS S DS + S DS S S S +
Sbjct: 656 SSDSSNSSNSSDSSDSSDSSDSSSSSDSSNSSDSSDSSDSSNSSESSDSSDSSDSDSSDS 715
Query: 2916 HGSAQEQLRDGSRHPRSHQEDRAGHGHSADSSRQSGTRHTQTSSGGQAASSHEQARSSAG 2975
S+ D S D + S+DSS S + + SS +S + S+
Sbjct: 716 SDSSNSNSSDSDSSNSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSD 775
Query: 2976 ERHGSHHQQSADSSRHSGIGHGQASSAVRDSGHRGYSGSQASDNEGHSEDSDTQSVSAHG 3035
S+ S DSS S SS +S S + + +S DS S S+
Sbjct: 776 SSDSSNSSDSNDSSNSSDSSDSSNSSDSSNSSDSSDSSDSSDSDSSNSSDSSNSSDSSDS 835
Query: 3036 QAGSHQQSHQESARGRSGETSGHSGSFLYQVSTHEQSESSHGWTGPSTRGRQGSRHEQAQ 3095
S +S+ G ++S S S S+ S+ + S+ + S +
Sbjct: 836 SNSSDSSDSSDSSDGSDSDSSNRSDSSNSSDSSDSSDSSNSSDSSDSSDSNESSNSSDSS 895
Query: 3096 DSSRHS------------------ASQYGQDTIRGHPGSSRGGRQGYHHEHSVDSSGHSG 3137
DSS S +S + + +S S DSS S
Sbjct: 896 DSSNSSDSDSSDSSNSSDSSDSSNSSDSSESSNSSDNSNSSDSSNSSDSSDSSDSSNSSD 955
Query: 3138 SHHSHTTSQGRSDASRGQSGSRSASRTTRNEEQSGDSSRHSVSRHHEASTHADISRHSQA 3197
S +S + S SD+S S S S + + S DSS S S S+ + S S
Sbjct: 956 SSNS-SDSSNSSDSSDSNSSDSSDSSNSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSD 1014
Query: 3198 VQGQSEGSRRSRRQGSSVSQDSDSEGHSEDSERWSGSASRNHRGSVQEQSRHGSRHPRSH 3257
S+ S S SS S DS S DS S S+ ++ + S S
Sbjct: 1015 SSNSSDSSNSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSD 1074
Query: 3258 HEDRAGHGHSADRSRQSGTRHAETSSGGQAASSHEQARSSPGERHGSRHQQSADSSRHSG 3317
D + S+D S S + + SS +S + S S S+DSS S
Sbjct: 1075 SSDSSDSSESSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSD 1134
Query: 3318 IPRGQASSAVRDSRHWGSSGSQASDSEGHSEESDTQSVSGHGQAGPHQQSHQESARDRSG 3377
SS DS S S +SDS S+ SD+ S + S S S
Sbjct: 1135 SSDSSNSSDSSDS----SESSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSS 1190
Query: 3378 GRSGRSGSFLYQVSTHEQSESAHGRTRTSTGRRQGSHHEQARDSSRHSASQEGQDTIRGH 3437
S S S + S+S+ + S+ S + DSS S S E D
Sbjct: 1191 DSSDSSDS-------SDSSDSSD--SSDSSDSSDSSDSSDSSDSSDSSDSNESSD----- 1236
Query: 3438 PGSSRRGRQGSHYEQSVDRSGHSGSHHSHTTSQGRSDASRGQSGSRSASRQTRNDEQSGD 3497
S S S D S S S S + S SD S+ +SG+ + + + + G
Sbjct: 1237 ---SSDSSDSSDSSNSSDSSDSSDSSDSTSDSNDESD-SQSKSGNGNNNGSDSDSDSEGS 1292
Query: 3498 GSRHSWS 3504
S HS S
Sbjct: 1293 DSNHSTS 1299
Score = 236 bits (602), Expect = 3e-61
Identities = 300/1337 (22%), Positives = 478/1337 (35%), Gaps = 121/1337 (9%)
Query: 2675 ASSAVRDSG---HRGYSGSQASDNEGHSEDSDTQSVSAHGQAGSHQQSHQESARGRSGET 2731
AS +++SG H G G Q + +GH G S G+S T
Sbjct: 50 ASGTIKESGVLVHEGDRGRQENTQDGHK--------------GEGNGSKWAEVGGKSFST 95
Query: 2732 SGHSGSFLYQVSTHEQSESSHGWTGPSTRGRQGSRHEQAQDSSRHSASQDGQDTIRGHPG 2791
Y +E+ + GW G + + A G D I G
Sbjct: 96 --------YSTLANEEG-NIEGWNGDTGK-----------------AETYGHDGIHGKEE 129
Query: 2792 S-SRGGRQGYHHEHSVDSSGHSG-SHHSHTTSQGRSDASRGQSGSRSASRTTRNEEQSGD 2849
+ + G QG +D++G + S+ + T + + G +G + +
Sbjct: 130 NITANGIQG--QVSIIDNAGATNRSNTNGNTDKNTQNGDVGDAGHNEDVAVVQEDGPQVA 187
Query: 2850 GSRHSGSRHHEASTHADISRHSQAVQGQSEGSRRSRRQGSSVSQDSDSEGHSEDSERWSG 2909
GS +S E + S ++ + S+R G+ ++ + G + G
Sbjct: 188 GSNNSTDNEDEIIEN---SCRNEGNTSEITPQINSKRNGTKEAEVTPGTGEDAGLDNSDG 244
Query: 2910 SASRNHHGSAQEQLRDGSRHPRSHQEDRAGHGH--SADSSRQSGTRHTQT----SSGGQA 2963
S S N A E +GS +++ AG+G S +S Q G H + SS GQ
Sbjct: 245 SPSGN---GADEDEDEGSG---DDEDEEAGNGKDSSNNSKGQEGQDHGKEDDHDSSIGQN 298
Query: 2964 ASSHEQARSSAGERHGSHHQQSADSSRHS-----GIGHGQASSAVRDSGHRGYSGSQASD 3018
+ S E E H++ D + S GI S + D+ + S+ +
Sbjct: 299 SDSKEYYDPEGKE--DPHNEVDGDKTSKSEENSAGIPEDNGSQRIEDTQKLNHRESKRVE 356
Query: 3019 NEGHSED-------SDTQSVSAHGQAGSHQQSHQESARGRSG-ETSGHSGSFLYQVSTHE 3070
N E S + + G + ++ +E +G G E G G L + +
Sbjct: 357 NRITKESETHAVGKSQDKGIEIKGPSSGNRNITKEVGKGNEGKEDKGQHGMILGKGNVKT 416
Query: 3071 QSESSHGWTGPSTRGRQGSRHEQAQDSSRHSASQYGQDTIRGHPGSSRGGRQGYHHEHSV 3130
Q E + GP + G++ + S ++ Y QG S
Sbjct: 417 QGEVVN-IEGPGQKSEPGNKVGHSNTGSDSNSDGYDSYDFDDK------SMQGDDPNSSD 469
Query: 3131 DSSGHSGSH-HSHTTSQGRSDASRGQ-----SGSRSASRTTRNEEQSGDSSRHSVSRHHE 3184
+S+G+ ++ S S R DAS +G+ S S+ +++ S ++ +
Sbjct: 470 ESNGNDDANSESDNNSSSRGDASYNSDESKDNGNGSDSKGAEDDDSDSTSDTNNSDSNGN 529
Query: 3185 ASTHADISRHSQAVQGQSEGSRRSRRQGSSVSQDSDS-EGHSEDSERWSGSASRNHRGSV 3243
+ D + S + +G+S+ S S+ S SDS + S DS S S S + S
Sbjct: 530 GNNGNDDNDKSDSGKGKSDSSDSDSSDSSNSSDSSDSSDSDSSDSNSSSDSDSSDSDSSD 589
Query: 3244 QEQSRHGSRHPRSHHEDRAGHGHSADRSRQSGTRHAETSSGGQAASSHEQARSSPGERHG 3303
S S D + S+D S S ++ SS ++ SS ++S + +
Sbjct: 590 SSDSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSK--SDSSKSESDSSDSDSKSDSSDSNS 647
Query: 3304 SRHQQSADSSRHSGIPRGQASSAVRDSRHWGSSGSQASDSEGHSEESDTQSVSGHGQAGP 3363
S ++DSS S SS DS S S +SDS S+ SD+ S ++
Sbjct: 648 SDSSDNSDSSDSSNSSNSSDSSDSSDS----SDSSSSSDSSNSSDSSDSSDSSNSSESSD 703
Query: 3364 HQQSHQESARDRSGGRSGRSGSFLYQVSTHEQSESAHGRTRTSTGRRQGSHHEQARDSSR 3423
S + D S + S S+S + S+ S + DSS
Sbjct: 704 SSDSSDSDSSDSSDSSNSNS------------SDSDSSNSSDSSDSSNSSDSSDSSDSSN 751
Query: 3424 HSASQEGQDTIRGHPGSSRRGRQGSHYEQSVDRSGHSGSHHSHTTSQGRSDASRGQSGSR 3483
S S + D+ S S + S S + + S SD+S S
Sbjct: 752 SSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSNDSSNSSDSSDSSNSSDSSNSSDSSD 811
Query: 3484 SASRQTRNDEQSGDGSRHSWSHHHEASTQADSSRHSQSGQGQSAGPRTSRNQGSSVSQDS 3543
S+ + S D S S S S+ + S S G + R+ + S S S
Sbjct: 812 SSDSSDSDSSNSSDSSNSSDSSDSSNSSDSSDSSDSSDGSDSDSSNRSDSSNSSDSSDSS 871
Query: 3544 DSQGHSEDSERWSGSASRNHRGSAQEQ-SRDGSRHPTSHHEDRAGHGHSAESSRQSGTHH 3602
DS S+ S+ + S N S+ S D +S+ D + +S++SS S +
Sbjct: 872 DSSNSSDSSDSSDSNESSNSSDSSDSSNSSDSDSSDSSNSSDSSDSSNSSDSSESSNSSD 931
Query: 3603 AENSSGGQAASSHEQARSSAGERHGSHHQQSADSSRHSGIGHGQASSAVRDSGHRGSS-G 3661
NSS +S + S+ S+ S++SS S +S + S SS
Sbjct: 932 NSNSSDSSNSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSNSSDSSDSSNSSDSSDSSDS 991
Query: 3662 SQASDSEGHSEDSDTQSVSAHGQAGPHQQSHQESTRGRSAGRSGRSGSFLYQVSTHEQSE 3721
S +SDS S SD+ S + S S S+ S S S S+
Sbjct: 992 SDSSDSSDSSNSSDSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSSDSSDSSDSSDSSDS 1051
Query: 3722 SAHGRAGPSTGGRQGSRHEQARDSSRHSASQEGQDTIRGHPGSRRGGRQGSYHEQSVDRS 3781
S + S+ S + DSS S S E D+ S S D S
Sbjct: 1052 SDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSESSDS-----SDSSNSSDSSDSSDSSDSS 1106
Query: 3782 GHSGSHHSHTTSQGRSDASHGQSGSRSASRETRNEEQSGDGSRHSGSRHHEASTQADSSR 3841
S S S +S + + S S S ++ N S D S S S S+ + S
Sbjct: 1107 DSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSSDSSESSDSSDSSDSSDSSDSS 1166
Query: 3842 HSQSGQGESAGSRRSRRQGSSVSQDSDSEAYPEDSERRSESASRNHHGSSREQSRDGSRH 3901
S S S S SS S DS + DS S+S+ + S + S D S
Sbjct: 1167 DSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSS-DSSDS 1225
Query: 3902 PGSSHRDTASHVQSSPVQSDSSTAKEHGHFSSLSQDSAYHSGIQSRGSPHSSSSYHYQSE 3961
SS + +S S SDSS + + SS S DS+ + + S S S + +
Sbjct: 1226 SDSSDSNESSDSSDSSDSSDSSNSSD----SSDSSDSSDSTSDSNDESDSQSKSGNGNNN 1281
Query: 3962 GTERQKGQSGLVWRHGS 3978
G++ G H +
Sbjct: 1282 GSDSDSDSEGSDSNHST 1298
Score = 236 bits (601), Expect = 4e-61
Identities = 290/1350 (21%), Positives = 497/1350 (36%), Gaps = 133/1350 (9%)
Query: 1869 RNEKQSGDGSRHSGSRHHEAS-SRADSSRHSQVGQGQSSGPRTSRNQGSSVSQDSDSQGH 1927
++E + + SG HE R ++++ G+G +G + + G S S S
Sbjct: 45 QDELNASGTIKESGVLVHEGDRGRQENTQDGHKGEG--NGSKWAEVGGKSFSTYSTLANE 102
Query: 1928 SEDSERWSGSASR----------------------------NHLGSAWEQSRDGSRHPGS 1959
+ E W+G + ++ G+ + +G+ +
Sbjct: 103 EGNIEGWNGDTGKAETYGHDGIHGKEENITANGIQGQVSIIDNAGATNRSNTNGNTDKNT 162
Query: 1960 HHEDRAGHGHSADSS--RQSGTRHTESSSRGQAASSHEQARSSAGERHGSHHQLQSADSS 2017
+ D GH+ D + ++ G + S++ + + ++ ++ G+ ++ +S
Sbjct: 163 QNGDVGDAGHNEDVAVVQEDGPQVAGSNN---STDNEDEIIENSCRNEGNTSEITPQINS 219
Query: 2018 RHSGIGHGQASSAV-RDSGHRGYSGSQASDSEGHSEDSDTQSVSAQGKAGPHQQSHKESA 2076
+ +G + + D+G GS + + G ED D S + + + + ++
Sbjct: 220 KRNGTKEAEVTPGTGEDAGLDNSDGSPSGN--GADEDEDEGSGDDEDEEAGNGKDSSNNS 277
Query: 2077 RGQSGESSGRSGSFLYQVSTHEQSESTHGQSAPSTGGRQGSHYDQAQDSSRHSASQEGQD 2136
+GQ G+ G+ + + S+ + G++ H + D + S S+E
Sbjct: 278 KGQEGQDHGKEDDHDSSIGQNSDSKEYYDPE-----GKEDPHNEV--DGDKTSKSEENSA 330
Query: 2137 TIRGHPGPSRGGRQGSHQEQSVDRSGHSGSHHSHTTSQGRSDASRGQSGSRSASRKTYDK 2196
I G R + R + + S T + G+S + S+ + K
Sbjct: 331 GIPEDNGSQRIEDTQKLNHRESKRVENRITKESETHAVGKSQDKGIEIKGPSSGNRNITK 390
Query: 2197 E--QSGDGSRHSGSHHHEASSWADSSRHSLV---GQGQSSGPRTSRPRGSSVSQDSDSEG 2251
E + +G G H ++ +V G GQ S P ++ S+ DS+S+G
Sbjct: 391 EVGKGNEGKEDKGQHGMILGKGNVKTQGEVVNIEGPGQKSEPG-NKVGHSNTGSDSNSDG 449
Query: 2252 H-SEDSERRSGSASRNHHGSAQEQSRDGSRHPRSHHEDRAGHGHSAESSRQSGTHHAENS 2310
+ S D + +S + + D + ++ R ++++ S+ +G + +S
Sbjct: 450 YDSYDFDDKSMQGDDPNSSDESNGNDDANSESDNNSSSRGDASYNSDESKDNG--NGSDS 507
Query: 2311 SGGQAASSHEQARSSAGERHGSHHQQSADSSRHSGIGHGQASSAVRDSGHRGSSGSQASD 2370
G + S + ++ + +G+ + + D+ + DSG +G S S SD
Sbjct: 508 KGAEDDDSDSTSDTNNSDSNGNGNNGNDDNDKS-------------DSG-KGKSDSSDSD 553
Query: 2371 SEGHSEDSDTQSVSAHGQAGPHQQSHQESTRGRSAGRSGRSGSFLYQVSTHEQSESAHGR 2430
S S SD+ S + + S +S+ S+S+
Sbjct: 554 SSDSSNSSDSSDSSDSDSSDSNSSSDSDSS----------------------DSDSSDSS 591
Query: 2431 TGTSTGGRQGSHHKQARDSSRHSTSQEGQDTIHGHPGSSSGGRQGSHYEQLVDRSGHSGS 2490
S+ S + DSS S S + D+ +S S S
Sbjct: 592 DSDSSDSSNSSDSSDSSDSSDSSDSSDSSDS----------------------KSDSSKS 629
Query: 2491 HHSHTTSQGRSDASHGHSGSRSASRQTRNDEQSGDGSRHSGSRHHEASSRADSSGHSQVG 2550
+ S +SD+S +S S + + + S + S S S SS + S +S
Sbjct: 630 ESDSSDSDSKSDSSDSNSSDSSDNSDSSDSSNSSNSSDSSDSSDSSDSSSSSDSSNSSDS 689
Query: 2551 QGQSEGPRTSRNWGSSFSQDSDSQGHSEDSERWSGSASRNHHGSAQEQLRDGSRHPRSHQ 2610
S+ +S + SS S DSD S DS S S S + S D S S
Sbjct: 690 SDSSDSSNSSESSDSSDSSDSD----SSDSSDSSNSNSSDSDSSNSSDSSDSSN--SSDS 743
Query: 2611 EDRAGHGHSADSSRQSGTRHTQTSSGGQAASSHEQARSSAGERHGSHHQQSADSSRHSGI 2670
D + +S+DSS S + ++ SS +S + +S+ S+ S+DSS S
Sbjct: 744 SDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSNDSSNSSDSSDSSNSSDS 803
Query: 2671 GHGQASSAVRDSGHRGYSGSQASDNEGHSEDSDTQSVSAHGQAGSHQQSHQESARGRSGE 2730
+ SS DS S S S N S DS S S+ S S R S
Sbjct: 804 SNSSDSSDSSDSSDSDSSNSSDSSNSSDSSDSSNSSDSSDSSDSSDGSDSDSSNRSDSSN 863
Query: 2731 TSGHSGSFLYQVSTHEQSESSHGWTGPSTRGRQGSRHEQAQDSSRHSASQDGQDTIRGHP 2790
+S S S ++ + S+SS ++ S + DSS S S D D+ +
Sbjct: 864 SSDSSDS-SDSSNSSDSSDSSDSNESSNSSDSSDSSNSSDSDSSDSSNSSDSSDS--SNS 920
Query: 2791 GSSRGGRQGYHHEHSVDSSGHSGSHHSHTTSQGRSDASRGQSGSRSASRTTRNEEQSGDG 2850
S + +S DSS S S S + S SD+S S S+ + N S D
Sbjct: 921 SDSSESSNSSDNSNSSDSSNSSDSSDS-SDSSNSSDSSNSSDSSNSSDSSDSNSSDSSDS 979
Query: 2851 SRHSGSRHHEASTHADISRHSQAVQGQSEGSRRSRRQGSSVSQDSDSEGHSEDSERWSGS 2910
S S S S+ + S S S+ S S SS S +S +S DS S S
Sbjct: 980 SNSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSSDS 1039
Query: 2911 ASRNHHGSAQEQLRDGSRHPRSHQEDRAGHGHSADSSRQSGTRHTQTSSGGQAASSHEQA 2970
+ + + + + S D + S+DSS S + + SS +S +
Sbjct: 1040 SDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSESSDSSDSSNSSDSSDS 1099
Query: 2971 RSSAGERHGSHHQQSADSSRHSGIGHGQASSAVRDSGHRGYSGSQASDNEGHSEDSDTQS 3030
S+ S S+DSS S SS DS S S +SD+ S+ SD+
Sbjct: 1100 SDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNS-SDSSDSSESSDSSDSSD 1158
Query: 3031 VSAHGQAGSHQQSHQESARGRSGETSGHSGSFLYQVSTHEQSESSHGWTGPSTRGRQGSR 3090
S + S S S ++S S S S+ S + S+ S
Sbjct: 1159 SSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSD 1218
Query: 3091 HEQAQDSSRHSASQYGQDTIRGHPGSSRGGRQGYHHEHSVDSSGHSGSHHSHTTSQGRSD 3150
+ DSS S S D+ S +S DSS S S S + S SD
Sbjct: 1219 SSDSSDSSDSSDSNESSDSSDSSDSSD--------SSNSSDSSDSSDSSDSTSDSNDESD 1270
Query: 3151 ASRGQSGSRSASRTTRNEEQSGDSSRHSVS 3180
S+ +SG+ + + + + + G S HS S
Sbjct: 1271 -SQSKSGNGNNNGSDSDSDSEGSDSNHSTS 1299
Score = 232 bits (592), Expect = 5e-60
Identities = 289/1328 (21%), Positives = 486/1328 (36%), Gaps = 108/1328 (8%)
Query: 274 SRHENTSQVPLQESRTRKRRGSRVSQ-DRDSEGHSEDSERHSGSASRNHHGSAWEQ--SR 330
+R + Q L S T K G V + DR + +++D + G+ GS W + +
Sbjct: 38 ARSNVSVQDELNASGTIKESGVLVHEGDRGRQENTQDGHKGEGN------GSKWAEVGGK 91
Query: 331 DGSRHPRSHDEDRASHGHSADSSRQSGTRHAETSSRGQTASSHE-QARSSPGERHGSGHQ 389
S + +E+ G + D+ + H + + +++ Q + S + G+ ++
Sbjct: 92 SFSTYSTLANEEGNIEGWNGDTGKAETYGHDGIHGKEENITANGIQGQVSIIDNAGATNR 151
Query: 390 QSADSSRHSATGRGQASSAVSDRGHRGS------SGSQASDSEGHSENSDTQSVSGHGKA 443
+ + + T G V D GH G Q + S ++N D +
Sbjct: 152 SNTNGNTDKNTQNGD----VGDAGHNEDVAVVQEDGPQVAGSNNSTDNEDEIIENSCRNE 207
Query: 444 GLRQQSHQESTRGRSGERSGRSGSSLYQVSTHEQPDSAHGRTGTSTGGRQGSHHEQ---- 499
G + + R+G + + + + D + G +GS ++
Sbjct: 208 GNTSEITPQINSKRNGTKEAEVTPGTGEDAGLDNSDGSPSGNGADEDEDEGSGDDEDEEA 267
Query: 500 --ARDSSRHSASQEGQDTIRGHPGSSRGGRQGSHHEQSVNRSGHSGSHHSHTTSQGRSDA 557
+DSS +S QEGQD G++ H + S+ ++ S ++ +G+ D
Sbjct: 268 GNGKDSSNNSKGQEGQDH----------GKEDDH-DSSIGQNSDSKEYYD---PEGKEDP 313
Query: 558 SHGQSGSRSASRQTRNEEQSGDGTRHSGSRHHEASSQADSSRHSQVGQGQSSGPRTSRNQ 617
+ G +++ ++EE S +GS+ E +Q + R S+ + + + +
Sbjct: 314 HNEVDGDKTS----KSEENSAGIPEDNGSQRIE-DTQKLNHRESKRVENRITKESETHAV 368
Query: 618 GSSVSQDSDSQGHSEDSERWSGSASRNHHGSAQEQSRD-----GSRHPRSHHEDRAGHGH 672
G S + + +G S + + + + G + G+ + + G G
Sbjct: 369 GKSQDKGIEIKGPSSGNRNITKEVGKGNEGKEDKGQHGMILGKGNVKTQGEVVNIEGPGQ 428
Query: 673 SADSSRKSGTRHTQNSSSGQAASSHE--------QARSSAGERHGSRHQLQSADSSRHSG 724
++ K G +T + S+ S++ +S+ E +G+ +D++ S
Sbjct: 429 KSEPGNKVGHSNTGSDSNSDGYDSYDFDDKSMQGDDPNSSDESNGNDDANSESDNNSSSR 488
Query: 725 TGHGQASSAVRDSGHRGSSGSQATDSEGHSEDSDTQSVSGHGQAGHHQQSHQESARDRSG 784
S +D+G+ S D + D++ +G+G G+ +S + +S
Sbjct: 489 GDASYNSDESKDNGNGSDSKGAEDDDSDSTSDTNNSDSNGNGNNGNDDNDKSDSGKGKSD 548
Query: 785 ERSRRSGSFLYQVSTHKQSESSHGWTGPSTGVRQGSHHEQARDNSRHSASQDGQDTIRGH 844
S + S+SS S+ S + + +S S+ D D+
Sbjct: 549 SSDSDSSD------SSNSSDSSDSSDSDSSDSNSSSDSDSSDSDSSDSSDSDSSDS---- 598
Query: 845 PGSSRRGRQGSHHEQSVDRSGHSGSHHSHTTSQGRSDASRGQSGSR-SASRTTRNEEQSR 903
S+ S D S S S S +S +SD+S+ +S S S S++ ++ S
Sbjct: 599 ----------SNSSDSSDSSDSSDSSDSSDSSDSKSDSSKSESDSSDSDSKSDSSDSNSS 648
Query: 904 DGSRHSGSRHHEASSHADISRHSQAGQGQSEGSRTSRRQGSSVSQDSDSEGHSEDSERWS 963
D S +S S SS++ S S S S +S SS S DS + S DS S
Sbjct: 649 DSSDNSDSSDSSNSSNSSDSSDSSDSSDSSSSSDSSNSSDSSDSSDSSNSSESSDSSDSS 708
Query: 964 GSASRNHRGSAQEQSRHGSRHPRSHHEDRAGHG---------HSADSSRQSGTPHAETSS 1014
S S + S+ S S D + +S+DSS S + ++ SS
Sbjct: 709 DSDSSDSSDSSNSNSSDSDSSNSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSNSSDSS 768
Query: 1015 GGQAASSHEQARSSPGERHGSRHQQSADSSRHSGIPRRQASSAVRDSGHWGSSGSQASDS 1074
+S + +S S S+DSS S SS DS SS S S +
Sbjct: 769 DSSDSSDSSDSSNSSDSNDSSNSSDSSDSSNSSDSSNSSDSSDSSDSSDSDSSNSSDSSN 828
Query: 1075 EGHSEESDTQSVSGHGQDGPHQQSHQESARDWSGGRSGRSGSFIYQVSTH--EQSESAHG 1132
S +S S S D S R S S S S S+ + S+S
Sbjct: 829 SSDSSDSSNSSDSSDSSDSSDGSDSDSSNRSDSSNSSDSSDSSDSSNSSDSSDSSDSNES 888
Query: 1133 RTRTSTGRRQGSHHEQARDSSRHSASQEGQDTIRAHPGSRRGGRQGSHHEQSVDRSGHSG 1192
+ + S + DSS S S + ++ + S S + S S
Sbjct: 889 SNSSDSSDSSNSSDSDSSDSSNSSDSSDSSNSSDSSESSNSSDNSNSSDSSNSSDSSDSS 948
Query: 1193 SHHSHTTSQGRSDASHGQSGSRSASRQTRKDKQSGDGSRHSGSRHHEAASWADSSRHSQV 1252
+ + S SD+S+ S S S + S D S S S +S + +S S
Sbjct: 949 DSSNSSDSSNSSDSSNSSDSSDSNSSDSSDSSNSSDSSDSSDSSDSSDSSDSSNSSDSSD 1008
Query: 1253 GQEQSSGSRTSRHQGSSVSQDS-DSERHSDDSERLSGSASRNHHGSSREQSRDGSRHPGF 1311
+ S S +S SS S +S DS SD S+ S +S + S S D S
Sbjct: 1009 SSDSSDSSNSSDSSNSSDSSNSSDSSDSSDSSD--SSDSSDSSDSSDSSNSSDSS----- 1061
Query: 1312 HQEDRASHGHSADSSRQSGTHHTESSSHGQAVSSHEQARSSPGERHGSRHQQSADSSRHS 1371
D + S+DSS S + + SS S+ + S S S+DSS S
Sbjct: 1062 ---DSSDSSDSSDSSDSSDSSDSSESSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSS 1118
Query: 1372 GIGHRQASSAVRDSGHRGSSGSQVTNSEGHSEDSDTQSVSAHGQAGPHQQSHKESARGQS 1431
+ SS DS S S +NS S+ S++ S + S S S
Sbjct: 1119 DSSNSSDSSDSSDS----SDSSDSSNSSDSSDSSESSDSSDSSDSSDSSDSSDSSDSSDS 1174
Query: 1432 GESSGRSRSFLYQVSSHEQSESTHGQTAPSTGGRQGSRHEQARNSSRHSASQDGQDTIRG 1491
+SS S S SS S ++ S+ S + +SS S S D D+
Sbjct: 1175 SDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDS--N 1232
Query: 1492 HPGSSRGGRQGSYHEQSVDRSGHSGYHHSHTTPQGRSDASHGQSGPRSASRQTRNEEQSG 1551
S S S D S S S + SD S +SG + + + + G
Sbjct: 1233 ESSDSSDSSDSSDSSNSSDSSDSSDSSDSTSDSNDESD-SQSKSGNGNNNGSDSDSDSEG 1291
Query: 1552 DGSRHSGS 1559
S HS S
Sbjct: 1292 SDSNHSTS 1299
Score = 221 bits (563), Expect = 1e-56
Identities = 293/1282 (22%), Positives = 472/1282 (36%), Gaps = 105/1282 (8%)
Query: 2760 RGRQGSRHEQAQDSSRHSASQDGQDTIRGHPGSS-------RGGRQGYHHEHS-VDSSGH 2811
RGRQ E QD + + + G S+ G +G++ + ++ GH
Sbjct: 66 RGRQ----ENTQDGHKGEGNGSKWAEVGGKSFSTYSTLANEEGNIEGWNGDTGKAETYGH 121
Query: 2812 SGSH--HSHTTSQGRSDASRGQSGSRSASRTTRNEEQSGDGSRHSGSRHHEASTHADISR 2869
G H + T+ G +GQ + T +G+ +++ + D
Sbjct: 122 DGIHGKEENITANG----IQGQVSIIDNAGATNRSNTNGNTDKNT-----QNGDVGDAGH 172
Query: 2870 HSQAVQGQSEGSRRSRRQGSSVSQDSDSEGHSEDSERWSGSASR-------NHHGSAQEQ 2922
+ Q +G + + GS+ S D++ E E+S R G+ S +G+ + +
Sbjct: 173 NEDVAVVQEDGPQVA---GSNNSTDNEDE-IIENSCRNEGNTSEITPQINSKRNGTKEAE 228
Query: 2923 LRDGSRHPRS-HQEDRAGHGHSADSSRQSGTRHTQTSSGGQAASSHEQARSSAGERHGSH 2981
+ G+ D + G+ AD G+ + G S ++ G+ HG
Sbjct: 229 VTPGTGEDAGLDNSDGSPSGNGADEDEDEGSGDDEDEEAGNGKDSSNNSKGQEGQDHGK- 287
Query: 2982 HQQSADSSRHSGIGHGQASSAVRD-----SGHRGYSGSQASDNEGHS----EDSDTQSVS 3032
+ S IG S D H G + S +E +S ED+ +Q +
Sbjct: 288 -----EDDHDSSIGQNSDSKEYYDPEGKEDPHNEVDGDKTSKSEENSAGIPEDNGSQRIE 342
Query: 3033 AHGQAGSHQQSHQESARGRSGETSGHSGSFLYQVSTHEQSESSHGWT---GPSTRGRQGS 3089
+ + +H+ES R + T + TH +S GPS+ R +
Sbjct: 343 -----DTQKLNHRESKRVENRITK--------ESETHAVGKSQDKGIEIKGPSSGNRNIT 389
Query: 3090 RHEQAQDSSRHSASQYGQDTIRGHPGSSRGGRQGYHHEHSVDSSGHSGSHHSHTTSQGRS 3149
+ + + Q+G +G+ ++G G+ H S+T S S
Sbjct: 390 KEVGKGNEGKEDKGQHGMILGKGNV-KTQGEVVNIEGPGQKSEPGNKVGH-SNTGSDSNS 447
Query: 3150 DASRG---QSGSRSASRTTRNEEQSGDSSRHSVSRHHEASTHADISRHSQAVQGQSEGSR 3206
D S ++E +G+ +S S ++ +S+ D S +S + GS
Sbjct: 448 DGYDSYDFDDKSMQGDDPNSSDESNGNDDANSESDNN-SSSRGDASYNSDESKDNGNGS- 505
Query: 3207 RSRRQGSSVSQDSDSEGHSEDSERWSGSASRNHRGSVQEQSRHGSRHPRSHHEDRAGHGH 3266
S ++D DS+ S D+ + + N+ ++S G S D + +
Sbjct: 506 -----DSKGAEDDDSDSTS-DTNNSDSNGNGNNGNDDNDKSDSGKGKSDSSDSDSSDSSN 559
Query: 3267 SADRSRQSGTRHAETSSGGQAASSHEQARSSPGERHGSRHQQSADSSRHSGIPRGQASSA 3326
S+D S S + ++++S + SS + S + S S+DSS S SS
Sbjct: 560 SSDSSDSSDSDSSDSNSSSDSDSSDSDSSDS-SDSDSSDSSNSSDSSDSSDSSDSSDSSD 618
Query: 3327 VRDSRHWGS-SGSQASDSEGHSEESDTQSVSGHGQAGPHQQSHQESARDRSGGRSGRSGS 3385
DS+ S S S +SDS+ S+ SD+ S + S+ ++ D S S
Sbjct: 619 SSDSKSDSSKSESDSSDSDSKSDSSDSNSSDSSDNSDSSDSSNSSNSSDSSDSSDSSDSS 678
Query: 3386 FLYQVSTHEQSESAHGRTRTSTGRRQGSHHEQARDSSRHSASQEGQDTIRGHPGSSRRGR 3445
S S + + +S + S S++ D+ + S
Sbjct: 679 SSSDSSNSSDSSDSSDSSNSSESSDSSDSSDSDSSDSSDSSNSNSSDSDSSNSSDSSDSS 738
Query: 3446 QGSHYEQSVDRSGHSGSHHS--HTTSQGRSDASRGQSGSRSASRQTRNDEQSGDGSRHSW 3503
S S D S S S S + S SD+S S S++ ND + S S
Sbjct: 739 NSSDSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSNDSSNSSDSSDS- 797
Query: 3504 SHHHEASTQADSSRHSQSGQGQSAGPRTSRNQGSSVSQDSDSQGHSEDSERWSGSASRNH 3563
S+ ++S +DSS S S S+ S N S S S+S S+ S+ GS S +
Sbjct: 798 SNSSDSSNSSDSSDSSDSSDSDSSNSSDSSNSSDS-SDSSNSSDSSDSSDSSDGSDSDSS 856
Query: 3564 RGSAQEQSRDGS-RHPTSHHEDRAGHGHSAESSRQSGTHHAENSSGGQAASSHEQARS-- 3620
S S D S +S+ D + S ESS S + + NSS ++ S + S
Sbjct: 857 NRSDSSNSSDSSDSSDSSNSSDSSDSSDSNESSNSSDSSDSSNSSDSDSSDSSNSSDSSD 916
Query: 3621 ------SAGERHGSHHQQSADSSRHSGIGHGQASSAVRDSGHRG-------SSGSQASDS 3667
S+ + S + S+DSS S SS DS + SS S +SDS
Sbjct: 917 SSNSSDSSESSNSSDNSNSSDSSNSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSNSSDS 976
Query: 3668 EGHSEDSDTQSVSAHGQAGPHQQSHQESTRGRSAGRSGRSGSFLYQVSTHEQSESAHGRA 3727
S SD+ S + S S S+ S S S S+ + S +
Sbjct: 977 SDSSNSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDS 1036
Query: 3728 GPSTGGRQGSRHEQARDSSRHSASQEGQDTIRGHPGSRRGGRQGSYHEQSVDRSGHSGSH 3787
S+ S + DSS S S + D+ S S +S D S S S
Sbjct: 1037 SDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSS--DSSDSSDSSESSDSSDSSNSS 1094
Query: 3788 HSHTTSQGRSDASHGQSGSRSASRETRNEEQSGDGSRHSGSRHHEASTQADSSRHSQSGQ 3847
S +S + S S S ++ N S D S S S S+ + S S
Sbjct: 1095 DSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSSDSSESSDSS 1154
Query: 3848 GESAGSRRSRRQGSSVSQDSDSEAYPEDSERRSESASRNHHGSSREQSRDGSRHPGSSHR 3907
S S S SS S DS + DS S+S+ + S + S D S SS
Sbjct: 1155 DSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSS-DSSDSSDSSDS 1213
Query: 3908 DTASHVQSSPVQSDSSTAKEHGHFSSLSQDSAYHSGIQSRGSPHSSSSYHYQSEGTERQK 3967
+S S SDSS + E S S S + S S SS S ++ ++ Q
Sbjct: 1214 SDSSDSSDSSDSSDSSDSNESSDSSDSSDSSDSSNSSDSSDSSDSSDSTSDSNDESDSQ- 1272
Query: 3968 GQSGLVWRHGSYGSADYDYGES 3989
+SG +GS +D + +S
Sbjct: 1273 SKSGNGNNNGSDSDSDSEGSDS 1294
Score = 196 bits (497), Expect = 5e-49
Identities = 241/1147 (21%), Positives = 415/1147 (36%), Gaps = 97/1147 (8%)
Query: 2857 RHHEASTHADI-SRHSQAVQGQSEGSRRSRRQGSSVSQ-DSDSEGHSEDSERWSGSASR- 2913
RH E S + + +R + +VQ + S + G V + D + +++D + G+ S+
Sbjct: 26 RHVEKSMNLHLLARSNVSVQDELNASGTIKESGVLVHEGDRGRQENTQDGHKGEGNGSKW 85
Query: 2914 NHHGSAQEQLRDGSRHPRSHQEDRAGHGHSADSSRQSGTRHTQTSSGGQAASSHEQARSS 2973
G + + E G A++ G + + +
Sbjct: 86 AEVGGKSFSTYSTLANEEGNIEGWNGDTGKAETYGHDGIHGKEENITANGIQGQVSIIDN 145
Query: 2974 AGERHGSHHQQSADSSRHSG----IGHGQASSAVRDSGHRGYSGSQASDNEGH------S 3023
AG + S+ + D + +G GH + + V++ G + + ++DNE
Sbjct: 146 AGATNRSNTNGNTDKNTQNGDVGDAGHNEDVAVVQEDGPQVAGSNNSTDNEDEIIENSCR 205
Query: 3024 EDSDTQSVSAHGQAGSHQQSHQESARGRSGETSGHSGSFLYQVSTHEQSESSHGWTGPST 3083
+ +T ++ + + E G +GE +G S + S S +G
Sbjct: 206 NEGNTSEITPQINSKRNGTKEAEVTPG-TGEDAGLDNS--------DGSPSGNGADEDED 256
Query: 3084 RGRQGSRHEQA---QDSSRHSASQYGQDTIRGHPGSSRGGRQGYHHEHSVDSSGHSGSHH 3140
G E+A +DSS +S Q GQD G +H S G +
Sbjct: 257 EGSGDDEDEEAGNGKDSSNNSKGQEGQD-------------HGKEDDHD-SSIGQNSDSK 302
Query: 3141 SHTTSQGRSDASRGQSGSRSASRTTRNEEQSGDSSRHSVSRHHEASTHADISRHSQAVQG 3200
+ +G+ D G + T+++EE S + S+ E + + R S+ V+
Sbjct: 303 EYYDPEGKEDPHNEVDGDK----TSKSEENSAGIPEDNGSQRIEDTQKLN-HRESKRVEN 357
Query: 3201 QSEGSRRSRRQGSSVSQDSDSEGHSEDSERWSGSASRNHRGSVQEQSRHG---------- 3250
+ + G S + + +G S + + + + G +++ +HG
Sbjct: 358 RITKESETHAVGKSQDKGIEIKGPSSGNRNITKEVGKGNEGK-EDKGQHGMILGKGNVKT 416
Query: 3251 --------SRHPRSHHEDRAGHGHSADRSRQSG---------TRHAETSSGGQAASSHEQ 3293
+S ++ GH ++ S G + + + ++ ++
Sbjct: 417 QGEVVNIEGPGQKSEPGNKVGHSNTGSDSNSDGYDSYDFDDKSMQGDDPNSSDESNGNDD 476
Query: 3294 ARSSPGERHGSRHQQSADSSRHSGIPRGQASSAVRDSRHWGSSGSQASDSEGHSE---ES 3350
A S SR S +S G S D +S + SDS G+ +
Sbjct: 477 ANSESDNNSSSRGDASYNSDESKDNGNGSDSKGAEDDDSDSTSDTNNSDSNGNGNNGNDD 536
Query: 3351 DTQSVSGHGQAGPHQQSHQESARDRSGGRSGRSGSFLYQVSTHEQSESAHGRTRTSTGRR 3410
+ +S SG G++ +S+ S S S S+ S + + +
Sbjct: 537 NDKSDSGKGKSDSSDSDSSDSSNSSDSSDSSDSDSSDSNSSSDSDSSDSDSSDSSDSDSS 596
Query: 3411 QGSHHEQARDSSRHSASQEGQDTIRGHPGSSRRGRQGSHYEQSVDRSGHSGSHHSHTTSQ 3470
S+ + DSS S S + D+ SS+ S + D S + S S +
Sbjct: 597 DSSNSSDSSDSSDSSDSSDSSDSSDSKSDSSKSESDSSDSDSKSDSSDSNSSDSSDNSDS 656
Query: 3471 GRSDASRGQSGSRSASRQTRNDEQSGDGSRHSWSHHHEASTQADSSRHSQSGQGQSAGPR 3530
SD+S + S S+ +D S S +S ++S +DSS S+S
Sbjct: 657 --SDSSNSSNSSDSSDSSDSSDSSSSSDSSNS----SDSSDSSDSSNSSESSDSSD---- 706
Query: 3531 TSRNQGSSVSQDSDSQGHSE-DSERWSGSASRNHRGSAQEQSRDGSRHPTSHHEDRAGHG 3589
S + SS S DS + S+ DS S S+ ++ + + S + +S D +
Sbjct: 707 -SSDSDSSDSSDSSNSNSSDSDSSNSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSNSS 765
Query: 3590 HSAESSRQSGTHHAENSSGGQAASSHEQARSSAGERHGSHHQQSADSSRHSGIGHGQASS 3649
S++SS S + + NSS +S+ + S+ S+ S+DSS S +S
Sbjct: 766 DSSDSSDSSDSSDSSNSSDSNDSSNSSDSSDSSNSSDSSNSSDSSDSSDSSDSDSSNSSD 825
Query: 3650 AVRDSGHRGSS-GSQASDSEGHSEDSDTQSVSAHGQAGPHQQSHQESTRGRSAGRSGRSG 3708
+ S SS S +SDS S+ SD+ S S + S S S+ S S
Sbjct: 826 SSNSSDSSDSSNSSDSSDSSDSSDGSDSDS-SNRSDSSNSSDSSDSSDSSNSSDSSDSSD 884
Query: 3709 SFLYQVSTHEQSESAHGRAGPSTGGRQGSRHEQARDSSRHSASQEGQDTIRGHPGSRRGG 3768
S +E S S+ ++ S + DSS S S + ++ S
Sbjct: 885 S-------NESSNSSDSSDSSNSSDSDSSDSSNSSDSSDSSNSSDSSESSNSSDNSNSSD 937
Query: 3769 RQGSYHEQSVDRSGHSGSHHSHTTSQGRSDASHGQSGSRSASRETRNEEQSGDGSRHSGS 3828
S S +S + + S SD+S S S S + + S D S S S
Sbjct: 938 SSNSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSNSSDSSDSSNSSDSSDSSDSSDSSDS 997
Query: 3829 RHHEASTQADSSRHSQSGQGESAGSRRSRRQGSSVSQDSDSEAYPEDSERRSESASRNHH 3888
S+ + S S S S S SS S DS + DS S+S+ ++
Sbjct: 998 SDSSNSSDSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSNS 1057
Query: 3889 GSSREQSRDGSRHPGSSHRDTASHVQSSPVQSDSSTAKEHGHFSSLSQDSAYHSGIQSRG 3948
S + S D S SS +S S SDSS + + S S S S
Sbjct: 1058 SDSSDSS-DSSDSSDSSDSSDSSDSSESSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSD 1116
Query: 3949 SPHSSSS 3955
S SS+S
Sbjct: 1117 SSDSSNS 1123
Score = 184 bits (468), Expect = 1e-45
Identities = 242/1082 (22%), Positives = 396/1082 (36%), Gaps = 99/1082 (9%)
Query: 2999 ASSAVRDSG---HRGYSGSQASDNEGHS-EDSDTQSVSAHGQAGS------HQQSHQESA 3048
AS +++SG H G G Q + +GH E + ++ G++ S +++ + E
Sbjct: 50 ASGTIKESGVLVHEGDRGRQENTQDGHKGEGNGSKWAEVGGKSFSTYSTLANEEGNIEGW 109
Query: 3049 RGRSG--ETSGHSGSFLYQVSTHEQSESSHGWTGP-STRGRQGSRHEQAQDSSRHSASQY 3105
G +G ET GH G + E++ +++G G S G+ + + + +Q
Sbjct: 110 NGDTGKAETYGHDG-----IHGKEENITANGIQGQVSIIDNAGATNRSNTNGNTDKNTQN 164
Query: 3106 GQDTIRGHPGS----SRGGRQGYHHEHSVDSSGH---SGSHHSHTTSQGRSDASRGQSGS 3158
G GH G Q +S D+ + + TS+ + ++G+
Sbjct: 165 GDVGDAGHNEDVAVVQEDGPQVAGSNNSTDNEDEIIENSCRNEGNTSEITPQINSKRNGT 224
Query: 3159 RSASRTTRNEEQSG-DSSRHSVSRH---------------HEASTHADISRHSQAVQGQS 3202
+ A T E +G D+S S S + EA D S +S+ +GQ
Sbjct: 225 KEAEVTPGTGEDAGLDNSDGSPSGNGADEDEDEGSGDDEDEEAGNGKDSSNNSKGQEGQD 284
Query: 3203 EGSRRSRRQGSSVSQDSDS------EGHSEDSERWSGS-ASRNHRGSVQEQSRHGSRHPR 3255
G SS+ Q+SDS EG + G S++ S +GS+ R
Sbjct: 285 HGKEDDH--DSSIGQNSDSKEYYDPEGKEDPHNEVDGDKTSKSEENSAGIPEDNGSQ--R 340
Query: 3256 SHHEDRAGHGHSADRSRQSGTRHAETSSGGQAASSHEQARS-SPGERH-----GSRHQQS 3309
+ H S R T+ +ET + G++ + + S G R+ G ++
Sbjct: 341 IEDTQKLNHRESK-RVENRITKESETHAVGKSQDKGIEIKGPSSGNRNITKEVGKGNEGK 399
Query: 3310 ADSSRHSGIPRGQASSAVRDSRHWGSSGSQASDSEGHSEESDTQSVSGHGQAGPHQQSHQ 3369
D +H G+ G+ + + + + EG ++S+ + GH G S
Sbjct: 400 EDKGQH-GMILGKGNVKTQ---------GEVVNIEGPGQKSEPGNKVGHSNTGSDSNS-- 447
Query: 3370 ESARDRSGGRSGRSGSFLYQVSTHEQSESAHGRTRTSTGRRQGSHHEQARDSSRHSASQE 3429
G Y + S G + SSR AS
Sbjct: 448 -------------DGYDSYDFDDKSMQGDDPNSSDESNGNDDANSESDNNSSSRGDASYN 494
Query: 3430 GQDTIRGHPGSSRRGRQGSHYEQSVD--RSGHSGSHHSHTTSQGRSDASRGQSGSRSASR 3487
++ GS +G + + + D S +G+ ++ +SD+ +G+S S +
Sbjct: 495 SDESKDNGNGSDSKGAEDDDSDSTSDTNNSDSNGNGNNGNDDNDKSDSGKGKSDSSDSDS 554
Query: 3488 QTRNDEQSGDGSRHSWSHHHEASTQADSSRHSQSGQGQSAGPRTSRNQGSSVSQDSDSQG 3547
++ S S S +S+ +DSS S S +S + SS S DS
Sbjct: 555 SDSSNSSDSSDSSDSDSSDSNSSSDSDSSDSDSSDSSDSDSSDSSNSSDSSDSSDSSDSS 614
Query: 3548 HSEDSERWSGSASRNHRGSAQEQSR-DGSRHPTSHHEDRAGHGHSAESSRQSGTHHAENS 3606
S DS +S++ S+ S+ D S +S D + S+ SS S + + +S
Sbjct: 615 DSSDSSDSKSDSSKSESDSSDSDSKSDSSDSNSSDSSDNSDSSDSSNSSNSSDSSDSSDS 674
Query: 3607 SGGQAASSHEQARSSAGERHGSHHQQSADSSRHSGIGHGQA--SSAVRDSGHRGSSGSQA 3664
S ++S + S+ S+ +S+DSS S + SS S S+ S +
Sbjct: 675 SDSSSSSDSSNSSDSSDSSDSSNSSESSDSSDSSDSDSSDSSDSSNSNSSDSDSSNSSDS 734
Query: 3665 SDSEGHSEDSDTQSVSAHGQAGPHQQSHQESTRGRSAGRSGRSGSFLYQVS-----THEQ 3719
SDS S+ SD+ S + S S S+ S S S S + +
Sbjct: 735 SDSSNSSDSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSNDSSNSSDS 794
Query: 3720 SESAHGRAGPSTGGRQGSRHEQARDSSRHSASQEGQDTIRGHPGSRRGGRQGSYHEQSVD 3779
S+S++ ++ S DSS S S D+ S S D
Sbjct: 795 SDSSNSSDSSNSSDSSDSSDSSDSDSSNSSDSSNSSDSSDSSNSSDSSDSSDSSDGSDSD 854
Query: 3780 RSGHSGSHHSHTTSQGRSDASHGQSGSRSASRETRNEEQSGDGSRHSGSRHHEAST---Q 3836
S S S +S +S ++ S S S E+ N S D S S S ++S
Sbjct: 855 SSNRSDSSNSSDSSDSSDSSNSSDSSDSSDSNESSNSSDSSDSSNSSDSDSSDSSNSSDS 914
Query: 3837 ADSSRHSQSGQGESAGSRRSRRQGSSVSQDSDSEAYPEDSERRSESASRNHHGSSREQSR 3896
+DSS S S + ++ + S+ S SDS S+ + S S N SS S
Sbjct: 915 SDSSNSSDSSESSNSSDNSNSSDSSNSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSNSS 974
Query: 3897 DGSRHPGSSHRDTASHVQSSPVQSDSSTAKEHGHFSSLSQDSAYHSGIQSRGSPHSSSSY 3956
D S SS +S S SDSS + + S S S +S S S S+SS
Sbjct: 975 DSSDSSNSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSS--NSSDSSNSSDSSNSSD 1032
Query: 3957 HYQSEGTERQKGQSGLVWRHGSYGSADYDYGESGFRHSQHGSVSYNSNPVVFKERSDICK 4016
S + S S S+D S S +S+ + SD
Sbjct: 1033 SSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSESSDSSDSSN 1092
Query: 4017 AS 4018
+S
Sbjct: 1093 SS 1094
Score = 154 bits (389), Expect = 2e-36
Identities = 161/721 (22%), Positives = 255/721 (35%), Gaps = 66/721 (9%)
Query: 87 ESTRKENLPISGHKHRKHSHHDKHEDNKQEENKENRKRPSSLERRNNRKGNKGRSKSPRE 146
ES ++ S S + D+ N N S ++ + S S
Sbjct: 630 ESDSSDSDSKSDSSDSNSSDSSDNSDSSDSSNSSNSSDSSDSSDSSDSSSSSDSSNSSDS 689
Query: 147 TGGKRHESSSEKKERKGYSPTHREEEYGKNHHNSSKKEKNKTENTRLGDNRKRLSERLEE 206
+ +SSE + S + + ++ NSS + + + ++ N S+ +
Sbjct: 690 SDSSDSSNSSESSDSSDSSDSDSSDSSDSSNSNSSDSDSSNSSDSSDSSNSSDSSDSSDS 749
Query: 207 KEDNEEGVYDYENTGRMTQKWIQSGHIATYYTIQDEAYDTTDSLLEENKIYERSRSSDGK 266
++ D++DS + + S SSD
Sbjct: 750 SNSSDSS-------------------------------DSSDS----SNSSDSSDSSDSS 774
Query: 267 SSSQVNRSRHENTSQVPLQESRTRKRRGSRVSQDRDSEGHSEDSERHSGSASRNHHGSAW 326
SS + S N S S + S S D S DS+ + S S N
Sbjct: 775 DSSDSSNSSDSNDSSNSSDSSDSSNSSDSSNSSDSSDSSDSSDSDSSNSSDSSNS----- 829
Query: 327 EQSRDGSRHPRSHDEDRASHGHSADSSRQSGTRHAETSSRGQTASSHEQARSSPGERHGS 386
S D S S D +S G +DSS +S + ++ SS +S+ + S S
Sbjct: 830 SDSSDSSNSSDSSDSSDSSDGSDSDSSNRSDSSNSSDSSDSSDSSNSSDSSDSSDSNESS 889
Query: 387 GHQQSADSSRHSATGRGQASSAVSDRGHRGSSGSQASDSEGHSENSDTQSVSGHGKAGLR 446
S+DSS S + +S+ S S+ S +S+S S+NS++ S +
Sbjct: 890 NSSDSSDSSNSSDSDSSDSSN--SSDSSDSSNSSDSSESSNSSDNSNSSDSSNSSDSSDS 947
Query: 447 QQSHQESTRGRSGERSGRSGSSLYQVSTHEQPDSAHGRTGTSTGGRQGSHHEQARDSSRH 506
S S S + S S SS ++ S + S+ S + DSS
Sbjct: 948 SDSSNSSDSSNSSDSSNSSDSS----DSNSSDSSDSSNSSDSSDSSDSSDSSDSSDSSNS 1003
Query: 507 SASQEGQDTIRGHPGSSRGGRQGSHHEQSVNRSGHSGSHHSHTTSQGRSDASHGQSGSRS 566
S S + D+ S S+ S N S S S S +S + S + S
Sbjct: 1004 SDSSDSSDS-----SDSSNSSDSSNSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSNSS 1058
Query: 567 ASRQTRNEEQSGDGTRHSGSRHHEASSQADSSRHSQVGQGQSSGPRTSRNQGSSVSQDSD 626
S + + S D + S S SS + S +S S +S + SS S DS
Sbjct: 1059 DSSDSSDSSDSSDSSDSSDSSDSSESSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSS 1118
Query: 627 SQGHSEDSERWSGSASRNHHGSAQEQSRDGSRHPRSHHEDRAGHGHSADSSRKSGTRHTQ 686
+S DS S S+ + ++ + S S D + S+DSS S + +
Sbjct: 1119 DSSNSSDSSDSSDSSDSSDSSNSSDSSDSSESSDSSDSSDSSDSSDSSDSSDSSDSSDSS 1178
Query: 687 NS--SSGQAASSHEQARSSAGERHGSRHQLQSADSSRHSGTGHGQASSAVRDSGHR---- 740
NS SS + SS S + + S S+DSS S + SS DS
Sbjct: 1179 NSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSNESSDSS 1238
Query: 741 ----GSSGSQATDSEGHSEDSDTQSVS-----GHGQAGHHQQSHQESARDRSGERSRRSG 791
S S ++DS S+ SD+ S S ++G+ + +S D G S S
Sbjct: 1239 DSSDSSDSSNSSDSSDSSDSSDSTSDSNDESDSQSKSGNGNNNGSDSDSDSEGSDSNHST 1298
Query: 792 S 792
S
Sbjct: 1299 S 1299
>gi|239743293 PREDICTED: mucin 12 [Homo sapiens]
Length = 5478
Score = 219 bits (559), Expect = 3e-56
Identities = 867/4017 (21%), Positives = 1338/4017 (33%), Gaps = 535/4017 (13%)
Query: 246 TTDSLLEENKIYERSRSSDGK------SSSQVNRSRHENTSQ-------VPLQESRTRKR 292
TT S + E RSR S++ SRH TS L + T
Sbjct: 985 TTSSGVSEESTTSRSRPGSTHTTAFPDSTTTPGLSRHSTTSHSSPGSTDTTLLPASTTTS 1044
Query: 293 RGSRVSQDRDSEGHSEDSERHSGSASRNHHG--SAWEQSRDGSRHPRSHDEDRASHGHSA 350
S+ S S S D+ GS + G S S GS H + S G
Sbjct: 1045 GPSQESTTSHSSSGSTDTALSPGSTTALSFGQESTTFHSNPGSTHTTLFPDSTTSSGIVE 1104
Query: 351 DSSRQSGTRHAETSSRGQTASSHEQARSSPGERHGSGHQQSADSSRHSATGRGQASSAVS 410
S+R H+ T S T S + +SPG + S Q+ +S H+ ++A
Sbjct: 1105 ASTRV----HSSTGSPRTTLSP--ASSTSPGLQGESTAFQTHPASTHTTPSPPSTATAPV 1158
Query: 411 DRG---HRGSSGSQ------ASDSEGHSENSDTQSVSGHGKAGLRQQSHQESTRGRSGER 461
+ HR + +S + GHSE S T S +G S +T GR
Sbjct: 1159 EESTTYHRSPGSTPTTHFPASSTTSGHSEKS-TIFHSSPDASGTTPSSAHSTTSGRGEST 1217
Query: 462 SGRSGSSLYQVSTHEQPDSAHGRTGTSTGGRQGSHHEQARDSSRHSASQ---EGQDTIRG 518
+ R +++T + G + ST S S E T R
Sbjct: 1218 TSRISPGSTEITTLPGSTTTPGLSEASTTFYSSPRSPTTTLSPASMTSLGVGEESTTSRS 1277
Query: 519 HPGSSRGG-------RQGSHHEQSVNRSGHSGSH------HSHTTSQGRSDAS--HGQSG 563
PGS+ G E + S GS HS TTS + + H +
Sbjct: 1278 QPGSTHSTVSPASTTTPGLSEESTTVYSSSRGSTETTVFPHSTTTSVHGEEPTTFHSRPA 1337
Query: 564 SRSASRQTRNEEQSG---DGTRHSGSRHHEASSQADSSRHSQVGQGQSSGPRTSRNQGSS 620
S + T + SG + T GS + + + +G+ ++ P +S + G+
Sbjct: 1338 STHTTLFTEDSTTSGLTEESTAFPGSPASTQTGLPATLTTADLGEESTTFPSSSGSTGTK 1397
Query: 621 VSQD-SDSQGHSEDSERWSGSASRNHHGSAQEQSRDGSRHPRSHHEDRAGHGHSADSSRK 679
+S S + G +S + SR S + + GS S E S S
Sbjct: 1398 LSPARSTTSGLVGES-----TPSRLSPSSTETTTLPGSPTTPSLSEKSTTFYTSPRSPDA 1452
Query: 680 SGTRHTQNSS--SGQAASSHEQARSSAGERHGSRHQLQSADSSRHSGTGHGQASSAVRDS 737
+ + T SS S ++++SH Q GS H DS+ S +S
Sbjct: 1453 TLSPATTTSSGVSEESSTSHSQP--------GSTHTTAFPDSTTTSDLSQEPTTS----- 1499
Query: 738 GHRGSSGSQATDSEGHSEDSDT--QSVSGHGQAGHHQQSHQESARDRSGERSRRSGSFLY 795
H ++AT S G + S QS + H G ++ + + SG
Sbjct: 1500 -HSSQGSTEATLSPGSTTASSLGQQSTTFHSSPG-------DTETTLLPDDTITSGLVEA 1551
Query: 796 QVSTHKQSESSHGWTGPSTGVRQGSHHEQARDNSRHSASQDGQDTIRGHPGSSRRGRQGS 855
TH + S H P++ G E S S+S DT PG++ + S
Sbjct: 1552 STPTHSSTGSLHTTLTPASSTSAGLQEESTTFQSWPSSS----DTTPSPPGTTAAPVEVS 1607
Query: 856 HHEQSVDRSGHSGSHHSHTTSQGRSDASRGQSGSRSASRTTRNEEQSRDG---SRHSGSR 912
S S + + +T+ GRS+ S S A+ T +S + S
Sbjct: 1608 TTYHSRPSSTPTTHFSASSTTLGRSEESTTVHSSPGATGTALFPTRSATSVLVGEPTTSP 1667
Query: 913 HHEASSHADISRHSQAGQGQSEGSRTSRRQGSSVSQDSDSEGHSEDSERWSGSASRNHRG 972
S+ S G SE S T S S D+ S S S ++ +H
Sbjct: 1668 ISSGSTETTALPGSTTTAGLSEKSTTF--YSSPRSPDTTLSPASTTSSGVSEESTTSH-- 1723
Query: 973 SAQEQSRHGSRHPRSHHEDRAGHGHSADSSRQSGTPHAETSSGGQAASSHEQARSSPGER 1032
SR GS H + G S++S H+ S S SS G
Sbjct: 1724 -----SRPGSTHTTAF----PGSTTMPGVSQESTASHSSPGSTDTTLSPGSTTASSLGPE 1774
Query: 1033 HGSRHQQSADSSRHSGIPRRQASSAVRDSGHWGSSGSQASDSEGHSEESDTQSVSGHGQD 1092
+ H S S+ + +P +S + ++ S+ +S H+ S S + G+
Sbjct: 1775 STTFHS-SPGSTETTLLPDNTTASGLLEA----STPVHSSTGSPHTTLSPAGSTTRQGES 1829
Query: 1093 GPHQQSHQESARDWSGGRSGRSGSFIYQVSTHEQSESAHGRTRTSTGRRQGSHHEQARDS 1152
Q S++D + +F+ +T S S+ T S E++ +
Sbjct: 1830 TTFQS--WPSSKDTMPAPPTTTSAFVELSTTSHGSPSSTPTTHFSASSTTLGRSEES--T 1885
Query: 1153 SRHSASQEGQDTIRAHPGSRRGGRQGSHHEQSVDRSGHSGSHHSH----TTSQGRSDASH 1208
+ HS+ T P R G E + S + H +T+ GRS+ S
Sbjct: 1886 TVHSSPVATATT----PSPARSTTSGLVEESTAYHSSPGSTQTMHFPESSTASGRSEESR 1941
Query: 1209 GQSGSR----SASRQTRKDKQSGDGSRHSGSRHHEAASWADSSRHSQVGQEQSSGSRTSR 1264
S S+ T S HS + DSS S E+S+ S +S+
Sbjct: 1942 TSHSSTTHTISSPPSTTSALVEEPTSYHSSPGSTATTHFPDSSTTSG-RSEESTASHSSQ 2000
Query: 1265 HQGSSVSQDSDSERHSDDSERLSGSASRNHHGSSREQSRDGSRH-PGFHQEDRASHGHSA 1323
++ + S E + S GS + GS PG ++ H
Sbjct: 2001 DATGTIVLPARSTTSVLLGESTTSPISS---GSMETTALPGSTTTPGLSEKSTTFHS--- 2054
Query: 1324 DSSRQSGTHHTESSSHGQAVSSHEQ-ARSSPGERHGSRHQQSADS---SRHSGIGHRQAS 1379
S R T + +S+ VS + S PG H + S + SRHS H
Sbjct: 2055 -SPRSPATTLSPASTTSSGVSEESTTSHSRPGSTHTTAFPDSTTTPGLSRHSTTSHSSPG 2113
Query: 1380 SAVRDSGHRGSSGSQVTNSEGHSEDSDTQSVSAHGQAGPHQQSHKESARGQSGESSGRSR 1439
S D+ +S T + G S++S T SH + S G +
Sbjct: 2114 ST--DTTLLPAS----TTTSGPSQESTT--------------SHSSPGSTDTALSPGSTT 2153
Query: 1440 SFLYQVSS---HEQSESTHGQTAPSTGGRQGSRHEQARNSSRHSASQDGQDTIRGHPGSS 1496
+ + S H STH P + G S+R +S T S+
Sbjct: 2154 ALSFGQESTTFHSSPGSTHTTLFPDSTTSSGI----VEASTRVHSSTGSPRTTLSPASST 2209
Query: 1497 RGGRQGSYHEQSVDRSGHSGYHHSHTTPQGRSDASHGQSGPRSASRQTRNEEQSGDGSRH 1556
G QG +S H +HTTP S A+ + R + + +
Sbjct: 2210 SPGLQG----ESTAFQTHPA--STHTTPSPPSTATAPVEESTTYHRSPGSTPTTHFPASS 2263
Query: 1557 SGSRHHEPSTRAGSSRHSQVGQGESAGSKTSRRQGSSVSQDRDSEGHSEDSERRSES--- 1613
+ S H E ST SS + SA S TS R S+ S R S G +E + +
Sbjct: 2264 TTSGHSEKSTIFHSSPDASGTTPSSAHSTTSGRGESTTS--RISPGSTEITTLPGSTTTP 2321
Query: 1614 ----ASRNHYGSAREQSRHGSRNPRSHQE----DRASHGHSAESSRQSGTRHAETSSGGQ 1665
AS Y S R + + +P S + ++ S S S A T++ G
Sbjct: 2322 GLSEASTTFYSSPRSPTT--TLSPASMTSLGVGEESTTSRSQPGSTHSTVSPASTTTPGL 2379
Query: 1666 AASSQEQARSSPGERHGSRHQQSADSSTDSGTGRRQDSSVVGDSGNRGSSGSQASDSEGH 1725
+ S SSPG S+ + R +SV G+ S ++ +
Sbjct: 2380 SEESTTVYSSSPG------------STETTVFPRTPTTSVRGEEPTTFHSRPASTHTTLF 2427
Query: 1726 SEESDTQSVSAHGQAGPHQQSHQESTRGQSGERSGRSGSFLYQVSTHEQSESAHGRTGPS 1785
+E+S T ++ A P + Q+G + + + L + ST S S G TG +
Sbjct: 2428 TEDSTTSGLTEESTAFPGSPAST-----QTGLPATLTTADLGEESTTFPSSS--GSTGTT 2480
Query: 1786 TGGRQRSRHEQARDS--SRHSASQEGQDTIRGHPGSSRGGRQGSHYEQSVDSSGHSGSHH 1843
+ + +S SR S S T+ G P + + + + S S + S
Sbjct: 2481 LSPARSTTSGLVGESTPSRLSPSSTETTTLPGSPTTPSLSEKSTTFYTSPRSPDATLSPA 2540
Query: 1844 SHTTS--QERSDVSRGQSGSRSVSRQTRNEKQSGDGSRHSGSRHHEASSRADSSRHSQVG 1901
+ T+S E S S Q GS + + G SRHS + H SS +
Sbjct: 2541 TTTSSGVSEESSTSHSQPGSTHTTAFPDSTTTPGL-SRHSTTSH---SSPGSTDTTLLPA 2596
Query: 1902 QGQSSGPRTSRNQGSSVSQDSDSQGHSEDSERWSGSASRNHLGSAWEQSRDGSRHPGSHH 1961
+SGP S S S S S D+ GS + G ++S PGS H
Sbjct: 2597 STTTSGP-------SQESTTSHSSPGSTDTALSPGSTTALSFG---QESTTFHSSPGSTH 2646
Query: 1962 EDRAGHGHSADSSRQSGTRHTESSSRGQAASSHEQARSSAGERHGSHHQLQSADSSRHSG 2021
++ ++ TR SS G ++ A S++ G Q+ +S H+
Sbjct: 2647 TTLFPDSTTSSGIVEASTR--VHSSTGSPRTTLSPASSTSPGLQGESTTFQTHPASTHTT 2704
Query: 2022 IGHGQASSAVRDSG---HRGYSGSQ------ASDSEGHSEDSDTQSVSAQGKAGPHQQSH 2072
++A + HR + +S + GHSE S S +H
Sbjct: 2705 PSPPSTATAPVEESTTYHRSPGSTPTTHFPASSTTSGHSEKSTIFHSSPDASGTTPSSAH 2764
Query: 2073 KE-SARGQSGESSGRSGSFLYQVSTHEQSESTHGQSAPSTGGRQGSHYDQAQDSSRHSAS 2131
S RG+S S GS +++T S +T G S ST + +S+
Sbjct: 2765 STTSGRGESTTSRISPGST--EITTLPGSTTTPGLSEAST--------------TFYSSP 2808
Query: 2132 QEGQDTIRGHPGPSRGGRQGSHQEQSVDRSGHSGSHHSHTTSQGRSDASRGQSGS----- 2186
+ T+ S G + S +S S HS + TT+ G S+ S S
Sbjct: 2809 RSPTTTLSPASMTSLGVGEESTTSRSQPGSTHSTVSPASTTTPGLSEESTTVYSSSPGST 2868
Query: 2187 ------RSASRKTYDKEQSGDGSRHSGSH---HHEASSWADSSRHSLVGQGQSSGPRTSR 2237
RS + +E + SR + +H E S+ + + S G + +T
Sbjct: 2869 ETTVFPRSTTTSVRGEEPTTFHSRPASTHTTLFTEDSTTSGLTEESTAFPGSPASTQTGL 2928
Query: 2238 PRG---SSVSQDSDSEGHSEDSERRSGSASRNHHGSAQEQSRDGSRHPRSHHEDRA-GHG 2293
P + + ++S + S S + S +R+ +S P S G
Sbjct: 2929 PATLTTADLGEESTTFPSSSGSTGTTLSPARSTTSGLVGESTPSRLSPSSTETTTLPGSP 2988
Query: 2294 HSAESSRQSGTHHAENSSGGQAASSHEQARSSAGERHGSHHQQSADSSRHSGIGHGQASS 2353
+ S +S T + S S S E + H Q + ++
Sbjct: 2989 TTPSLSEKSTTFYTSPRSPDATLSPATTTSSGVSEESSTSHSQPGSTH----------TT 3038
Query: 2354 AVRDSGHRGSSGSQASDSEGHSEDSDTQSVSAHGQAGPHQQSHQESTRGRSAGRSGR--- 2410
A DS +SG + HS T++ + G Q +T S G +
Sbjct: 3039 AFPDS--TTTSGLSQEPTASHSSQGSTEATLSPGSTTASSLGQQSTTFHSSPGDTETTLL 3096
Query: 2411 ------SGSFLYQVSTHEQSESAHGR----TGTSTGGRQGSHHKQARDSSRHSTSQ---- 2456
SG TH + S H + TS G ++ S Q+ SS +T
Sbjct: 3097 PDDTITSGLVEASTPTHSSTGSLHTTLTPASSTSAGLQEESTTFQSWPSSSDTTPSPPGT 3156
Query: 2457 -----EGQDTIHGHPGSSSGGRQGSHYEQLVDRSGHSGSHHSHTTSQGRS---------- 2501
E T H P SS+ S + RS S + HS + G +
Sbjct: 3157 TAAPVEVSTTYHSRP-SSTPTTHFSASSTTLGRSEESTTVHSSPGATGTALFPTRSATSV 3215
Query: 2502 -----DASHGHSGSRSASRQTRNDEQSGDGSRHSGSRHHEASSRADSSGHSQVGQGQSEG 2556
S SGS + + +G + + S S S G SE
Sbjct: 3216 LVGEPTTSPISSGSTETTALPGSTTTAGLSEKSTTFYSSPRSPDTTLSPASTTSSGVSEE 3275
Query: 2557 PRTSRNWGSS-----FSQDSDSQGHSEDSERWSGSASRNHHGSAQEQLRDGSRHPRSHQE 2611
TS + S F + G S++S +AS + GS L GS S
Sbjct: 3276 STTSHSRPGSTHTTAFPGSTTMPGVSQES-----TASHSSPGSTDTTLSPGSTTASSLGP 3330
Query: 2612 DRAGHGHSADSSRQSGTRHTQTSSGGQAASSHEQARSSAGERH------GSHHQQSADSS 2665
+ HS S ++ T++ G +S SS G H GS +Q ++
Sbjct: 3331 ESTTF-HSGPGSTETTLLPDNTTASGLLEAS-TPVHSSTGSPHTTLSPAGSTTRQGESTT 3388
Query: 2666 RHSGIGHGQASSA----------VRDSGHRGYSG------SQASDNEGHSEDSDTQSVSA 2709
S + A + + H S S +S G SE+S T S
Sbjct: 3389 FQSWPNSKDTTPAPPTTTSAFVELSTTSHGSPSSTPTTHFSASSTTLGRSEESTTVHSSP 3448
Query: 2710 HGQAGSHQQSHQESARGRSGETSGHSGSFLYQVSTHEQSESSHGWTGPSTRGRQGSRHEQ 2769
A + + ++ T+ HS Q +S+++ G ST + H
Sbjct: 3449 VATATTPSPARSTTSGLVEESTTYHSSPGSTQTMHFPESDTTSGRGEESTTSHSSTTHTI 3508
Query: 2770 AQDSSRHSASQDGQDTIRGHPGSSRGGRQGYHHEHSVDSSGHS----GSHHSH------- 2818
+ S SA + + PGS+ H S +SG S SH S
Sbjct: 3509 SSAPSTTSALVEEPTSYHSSPGST----ATTHFPDSSTTSGRSEESTASHSSQDATGTIV 3564
Query: 2819 -----TTS--QGRSDASRGQSGSRSASRTTRNEEQSGDGSRHSGSRHHEASTHADISRHS 2871
TTS G S S SGS + + G + + S +S S
Sbjct: 3565 LPARSTTSVLLGESTTSPISSGSMETTALPGSTTTPGLSEKSTTFHSSPRSPATTLSPAS 3624
Query: 2872 QAVQGQSEGSRRSRRQGSSVSQDSDSEGHSEDSERWSGSASRNHHGSAQEQLRDGSRHPR 2931
G SE S S + S + + + + S + GS L S
Sbjct: 3625 TTSSGVSEESTTSHSRPGSTHTTAFPDSTTTPGLSRHSTTSHSSPGSTDTTLLPASTTTS 3684
Query: 2932 -SHQEDRAGHGHSADSSRQSGTRHTQTSSGGQAASSHEQARSSAGERHGSHHQQSADSSR 2990
S QE H S + T S GQ +++ SS G H + S SS
Sbjct: 3685 GSSQESTTSHSSSGSTDTALSPGSTTALSFGQESTTF---HSSPGSTHTTLFPDSTTSSG 3741
Query: 2991 --------HSGIGHGQASSAVRDSGHRGYSGS----QASDNEGHSEDSDTQSVSA----- 3033
HS G + + + S G G Q H+ S + +A
Sbjct: 3742 IVEASTRVHSSTGSPRTTLSPASSTSPGLQGESTAFQTHPASTHTTPSPPSTATAPVEES 3801
Query: 3034 ---HGQAGSHQQSHQESARGRSGETSGHSGSFLYQVSTHEQSESSHGWTGPSTRGRQGSR 3090
H GS +H + S TSGHS S+ + S ++ +T GR S
Sbjct: 3802 TTYHRSPGSTPTTHFPA----SSTTSGHSEKSTIFHSSPDASGTTPSSAHSTTSGRGEST 3857
Query: 3091 HEQAQDSSRHSASQYGQDTIRGHPGSSRGGRQGYHH-------------------EHSVD 3131
+ S + G T PG S Y E S
Sbjct: 3858 TSRISPGSTEITTLPGSTTT---PGLSEASTTFYSSPRSPTTTLSPASMTSLGVGEESTT 3914
Query: 3132 SSGHSGSHHS-----HTTSQGRSDASRGQSGSRSASRTTRNEEQSGDSS--RHSVSRHHE 3184
S GS HS TT+ G S+ S S S T +S +S R + H
Sbjct: 3915 SRSQPGSTHSTVSPASTTTPGLSEESTTVYSSSPGSTETTVFPRSTTTSVRREEPTTFHS 3974
Query: 3185 --ASTHADISRHSQAVQGQSE------GSRRSRRQG-------SSVSQDSDSEGHSEDSE 3229
ASTH + G +E GS S + G + + ++S + S S
Sbjct: 3975 RPASTHTTLFTEDSTTSGLTEESTAFPGSPASTQTGLPATLTTADLGEESTTFPSSSGST 4034
Query: 3230 RWSGSASRNHRGSVQEQSRHGSRHPRSHHEDR-AGHGHSADRSRQSGTRHAETSSGGQAA 3288
S +R+ + +S P S G + S +S T + S
Sbjct: 4035 GTKLSPARSTTSGLVGESTPSRLSPSSTETTTLPGSPTTPSLSEKSTTFYTSPRSPDATL 4094
Query: 3289 SSHEQARSSPGERHGSRHQQSADSSRHSGIPRGQASSAVRDSRHWGSSGSQASDSEGHSE 3348
S S E + H Q P ++A DS +SG + HS
Sbjct: 4095 SPATTTSSGVSEESSTSHSQ----------PGSTHTTAFPDST--TTSGLSQEPTTSHSS 4142
Query: 3349 ESDTQSVSGHGQAGPHQQSHQESARDRSGGRSG---------RSGSFLYQVSTHEQSESA 3399
+ T++ G Q + S G + SG TH + S
Sbjct: 4143 QGSTEATLSPGSTTASSLGQQSTTFHSSPGDTETTLLPDDTITSGLVEASTPTHSSTGSL 4202
Query: 3400 HGRTRTSTGRRQGSHHEQARDSSRHSASQEGQDTIRGHPGSSRRGRQGSHYEQSVDRSGH 3459
H ++ G E S S+S DT P ++ + S S S
Sbjct: 4203 HTTLTPASSTSTGLQEESTTFQSWPSSS----DTTPSPPSTTAVPVEVSTTYHSRPSSTP 4258
Query: 3460 SGSHHSHTTSQGRSDASRGQSGSRSASRQTRNDEQSGDG---SRHSWSHHHEASTQADSS 3516
+ + +T+ GRS+ S S A+ +S + S ST+ +
Sbjct: 4259 TTHFSASSTTLGRSEESTTVHSSPGATGTALFPTRSATSVLVGEPTTSPISSGSTETTAL 4318
Query: 3517 RHSQSGQGQSAGPRTSRNQGSSVSQDSDSQGHSEDSERWSGSASRNHRGSAQEQSRDGSR 3576
S + G S +++ S S D+ S S S ++ +H SR GS
Sbjct: 4319 PGSTTTAGLS--EKSTTFYSSPRSPDTTLSPASTTSSGVSEESTTSH-------SRPGSM 4369
Query: 3577 HPTSHHEDRAGHGHSAESSRQSGTHHAENSSGGQAASSHEQARSSAGERHGSHHQQSA-- 3634
H T+ G S ES+ H+ S S SS G + H
Sbjct: 4370 HTTAFPSSTTMPGVSQEST----ASHSSPGSTDTTLSPGSTTASSLGPESTTFHSSPGST 4425
Query: 3635 ------DSSRHSGIGHGQASSAVRDS-GHRGSSGSQASDSEGHSEDSDTQSVSAHGQAGP 3687
D++ SG+ +AS+ V S G ++ S A + E + QS P
Sbjct: 4426 ETTLLPDNTTASGL--LEASTPVHSSTGSPHTTLSPAGSTTRQGESTTFQSWPNSKDTTP 4483
Query: 3688 HQQSHQESTRGRSAGRSGRSGSFLYQVSTH-EQSESAHGRAGPSTGGRQGSRHEQARDSS 3746
+ + S G S +TH S + GR+ ST S
Sbjct: 4484 APPTTTSAFVELSTTSHGSPSS---TPTTHFSASSTTLGRSEESTTVHSSPVATATTPSP 4540
Query: 3747 RHSASQ---EGQDTIRGHPGSRRGGRQGSYHEQSVDRSG--------HSGSHHSHTTSQG 3795
S + E T PGS Q + +S SG HS + H+ +++
Sbjct: 4541 ARSTTSGLVEESTTYHSSPGS----TQTMHFPESNTTSGRGEESTTSHSSTTHTISSAPS 4596
Query: 3796 RSDASHGQSGSRSASRETRNEEQSGDGSRHSGSRHHEASTQADSSRHSQSGQGESAGSRR 3855
+ A + S +S + D S SG E ST + SS+ + A S
Sbjct: 4597 TTSALVEEPTSYHSSPGSTATTHFPDSSTTSG--RSEESTASHSSQDATGTIVLPARSTT 4654
Query: 3856 SRRQGSSV-----SQDSDSEAYPEDSER--RSESASRNHHGSSREQSRDGSRHPGSSHR- 3907
S G S S ++ A P + SE ++ H S + S + R
Sbjct: 4655 SVLLGESTTSPISSGSMETTALPGSTTTPGLSEKSTTFHSSPSSTPTTHFSASSTTLGRS 4714
Query: 3908 DTASHVQSSPVQSDSSTAKEHGHFSSLSQDS-AYHSGIQSRGSPHSSSSYHYQSEGT 3963
+ ++ V SSPV + ++ + S L ++S AYHS SP S+ + H+ T
Sbjct: 4715 EESTTVHSSPVATATTPSPARSTTSGLVEESTAYHS------SPGSTQTMHFPESST 4765
Score = 211 bits (536), Expect = 2e-53
Identities = 805/3880 (20%), Positives = 1272/3880 (32%), Gaps = 518/3880 (13%)
Query: 331 DGSRHPRSHDEDRASHGHSADSSRQSGTRHAETS------SRGQTASSHEQARSSPGERH 384
D S + +E SH + H+ TS S+ + + PG
Sbjct: 213 DSSTNSGHSEESTVSHSGPGATGTTLFPSHSATSVFVGEPKTSPITSASMETTALPGSTT 272
Query: 385 GSGHQQSADSSRHSATGRGQASSAVSDRGHRGSSGSQASDSEGHSENSDTQSVSGHGKAG 444
+G + + + S + S SSG + HS T +++
Sbjct: 273 TAGLSEKSTTFYSSPRSPDRTLSPARTT----SSGVSEKSTTSHSRPGPTHTIAFPDSTT 328
Query: 445 LRQQSHQESTRGRSGERSGRSGSSLYQVSTHEQPDSAHGRTGTSTGGRQG-SHHEQARDS 503
+ S QEST S GS+ +S S+ G T+ G + + D+
Sbjct: 329 MPGVS-QESTASHS-----IPGSTDTTLSPGTTTPSSLGPESTTFHSSPGYTKTTRLPDN 382
Query: 504 SRHSASQEGQDTIRGHPGSSRGGRQGSHHEQSVNRSGHSGSHHSHTTSQGRSDASHGQSG 563
+ S E + GS S S G + S +S+ S A G +
Sbjct: 383 TTTSGLLEASTPVHSSTGSPHTTLSPS---SSTTHEGEPTTFQSWPSSKDTSPAPSGTTS 439
Query: 564 SRSASRQTRNEEQSGDGTRHSGSR-----HHEASSQADSSRHSQVGQGQSSGPRTS---- 614
+ T + S T H + H E S+ SS + + TS
Sbjct: 440 AFVKLSTTYHSSPSSTPTTHFSASSTTLGHSEESTPVHSSPVATATTPPPARSATSGHVE 499
Query: 615 ------RNQGSSVS----QDSDSQGHSEDSERWSGSASRNHHGSAQEQSRDGSRHPRSHH 664
R+ GS+ + + S + GHSE+S + GS + H + S + S+H
Sbjct: 500 ESTAYHRSPGSTQTMHFPESSTTSGHSEESATFHGSTT---HTKSSTPSTTAALAHTSYH 556
Query: 665 EDRAG--HGHSADSSRKSGTRHTQNSSSGQAASSHEQARSSAGERHGSRHQLQSADSSRH 722
H DSS SG S +A+ S A ++ GS + DS+
Sbjct: 557 SSLGSTETTHFRDSSTISG-----RSEESKASHSSPDAMATTVLPAGSTPSVLVGDSTPS 611
Query: 723 SGTGHGQASSAVRDSGHRGSSGSQATDSEGHSEDSDTQSVSGHGQAGHHQQSHQESARDR 782
+ ++A+ S T G SE S T S H + S
Sbjct: 612 PISSGSMETTALPGS----------TTKPGLSEKSTTFYSSPRSPDTTHLPASMTS---- 657
Query: 783 SGERSRRSGSFLYQVSTHKQSESSHGWTGPSTGVRQGSHHEQARDNSRHSASQDGQDTIR 842
SG ++H + S+H P + G E S S S G
Sbjct: 658 -------SGVSEESTTSHSRPGSTHTTAFPGSTTMPGLSQE-----STASHSSPGPTDTT 705
Query: 843 GHPGSSRRGRQGSHHEQSVDRSGHSGSH--HSHTTSQGRSDASRGQSGSRSASRTTRNEE 900
PGS+ G + R G + + +TT+ G +AS S + TT +
Sbjct: 706 LSPGSTTASSLGPEYTTFHSRPGSTETTLLPDNTTASGLLEASMPVHSSTRSPHTTLSPA 765
Query: 901 QSRDGSRHSGSRHHEASSHADISRHSQAGQGQSEGSRTSRRQGSS-----VSQDSDSEGH 955
S S + H SS E S TS SS +S S + G
Sbjct: 766 GSTTRQGESTTFHSWPSSKDTRPAPPTTTSAFVEPSTTSHGSPSSIPTTHISARSTTSGL 825
Query: 956 SEDSERWSGSASRNHRGSAQEQSRHGSRHPRSHHEDRAGHGHSADSSRQSGTPHAETSSG 1015
E+S + H Q+ H P S + +G G + +S S T H +S+
Sbjct: 826 VEESTTY-------HSSPGSTQTMH---FPES--DTTSGRGEESTTS-HSSTTHTISSAP 872
Query: 1016 GQAASSHEQARSSPGERHGSRHQQSADSSRHSGIPRRQASSAVRDSGHWGSSGSQASDSE 1075
++ E+ S + DSS SG R + S+A S A+ +
Sbjct: 873 STTSALVEEPTSYHSSPGSTATTHFPDSSTTSG--RSEESTA-------SHSSQDATGTI 923
Query: 1076 GHSEESDTQSVSGHGQDGPHQQSHQES----ARDWSGGRSGRSGSFIYQVSTHEQSESAH 1131
S T + G P E+ + G S RS +F S + +
Sbjct: 924 VLPARSTTSVLLGESTTSPISSGSMETTALPGSTTTPGLSERSTTF--HSSPRSPATTLS 981
Query: 1132 GRTRTSTGRRQGSHHEQARDSSRHSASQEGQDTIRAHPGSRRGGRQGSHHEQSVDRSGHS 1191
+ TS+G + S ++R S H+ + T PG R HS
Sbjct: 982 PASTTSSGVSEESTTSRSRPGSTHTTAFPDSTTT---PGLSR----------------HS 1022
Query: 1192 GSHHSHTTSQGRSDASHGQSGSRSASRQTRKDKQSGDGSRHSGSRHHEAASWADSSRHSQ 1251
+ HS S G +D + AS T Q S HS S + A S+
Sbjct: 1023 TTSHS---SPGSTDTT-----LLPASTTTSGPSQESTTS-HSSSGSTDTALSPGSTTALS 1073
Query: 1252 VGQEQSSGSRTSRHQGSSVSQDSDSERHSDDSERLSGSASRNHH--GSSREQ-SRDGSRH 1308
GQE ++ +++ DS + S + +++R H GS R S S
Sbjct: 1074 FGQESTTFHSNPGSTHTTLFPDSTT------SSGIVEASTRVHSSTGSPRTTLSPASSTS 1127
Query: 1309 PGFHQEDRASHGHSADSSRQSGTHHTESSSHGQAVSSHEQARSSPGERHGSRHQQSADSS 1368
PG E A H A + T ++ ++ + H S+P H ++ S
Sbjct: 1128 PGLQGESTAFQTHPASTHTTPSPPSTATAPVEESTTYHRSPGSTP-TTHFPASSTTSGHS 1186
Query: 1369 RHSGIGHRQASSAVRDSGHRGSSGSQVTNSEGHSEDS-----DTQSVSAHGQAGPHQQSH 1423
S I H S+ SG SS T+ G S S T+ + G S
Sbjct: 1187 EKSTIFH----SSPDASGTTPSSAHSTTSGRGESTTSRISPGSTEITTLPGSTTTPGLSE 1242
Query: 1424 KESARGQSGESSGRSRSFLYQVSSHEQSESTHGQTAPSTGGRQGSRHEQARNSSRHSASQ 1483
+ S S + S S EST ++ P GS H +S +
Sbjct: 1243 ASTTFYSSPRSPTTTLSPASMTSLGVGEESTTSRSQP------GSTHSTVSPASTTTPGL 1296
Query: 1484 DGQDTIRGHPGSSRGGRQGSYHEQSVDRSGHSGYHHSHTTPQGRSDASHGQSGPRSASRQ 1543
+ T SSRG + + S S H TT R ++H ++
Sbjct: 1297 SEESTT--VYSSSRGSTETTVFPHSTTTSVHG---EEPTTFHSRPASTHTTLFTEDSTTS 1351
Query: 1544 TRNEEQSGDGSRHSGSRHHEPSTRAGSSRHSQVGQGESAGSKTSRRQGSSVSQDRDSEGH 1603
EE + + ++ P+T + +G+ + +S G+ +S R
Sbjct: 1352 GLTEESTAFPGSPASTQTGLPATLT----TADLGEESTTFPSSSGSTGTKLSPAR----- 1402
Query: 1604 SEDSERRSESA-SRNHYGSAREQSRHGSRNPRSHQEDRASHGHSAESSRQSGTRHAETSS 1662
S S ES SR S + GS S E + S S + + TSS
Sbjct: 1403 STTSGLVGESTPSRLSPSSTETTTLPGSPTTPSLSEKSTTFYTSPRSPDATLSPATTTSS 1462
Query: 1663 GGQAASSQEQARSSPGERHGSRHQQSADSSTDSGTGRRQDSSVVGDSGNRGSSGSQASDS 1722
G SS + S PG H + DS+T S + +S ++GS+ + S
Sbjct: 1463 GVSEESS--TSHSQPGSTHTTAF---PDSTTTSDLSQEPTTS----HSSQGSTEATLSPG 1513
Query: 1723 EGHSEESDTQSVSAHGQAGPHQQSHQESTRGQSGERSGRSGSFLYQVSTHEQSESAHGRT 1782
+ QS + H G ++ + + SG TH + S H
Sbjct: 1514 STTASSLGQQSTTFHSSPG-------DTETTLLPDDTITSGLVEASTPTHSSTGSLHTTL 1566
Query: 1783 GPSTGGRQRSRHEQARDSSRHSASQEGQDTIRGHPGSSRGGRQGSHYEQSVDSSGHSGSH 1842
P++ + E S S+S DT PG++ V ++ HS
Sbjct: 1567 TPASSTSAGLQEESTTFQSWPSSS----DTTPSPPGTTAA-------PVEVSTTYHSRPS 1615
Query: 1843 HSHTTSQERSDVSRGQSGSRSVSRQTRNEKQSGDGSRHSGSRHHEASSRADSSRHSQVGQ 1902
+ TT S + G RS T + G+ +R S+ VG+
Sbjct: 1616 STPTTHFSASSTTLG----RSEESTTVHSSPGATGTALFPTR---------SATSVLVGE 1662
Query: 1903 GQSSGPRTSRNQGSSVSQDSDSQGHSEDSERWSGS----------ASRNHLGSAWEQSRD 1952
+S + + +++ + + G SE S + S AS G + E +
Sbjct: 1663 PTTSPISSGSTETTALPGSTTTAGLSEKSTTFYSSPRSPDTTLSPASTTSSGVSEESTTS 1722
Query: 1953 GSRHPGSHHEDRAGHGHSADSSRQSGTRHTESSSRGQAASSHEQARSSAGERHGSHHQLQ 2012
SR +H G S++S H+ S S SS G + H
Sbjct: 1723 HSRPGSTHTTAFPGSTTMPGVSQESTASHSSPGSTDTTLSPGSTTASSLGPESTTFH--S 1780
Query: 2013 SADSSRHSGIGHGQASSAVRDSGHRGYSGSQASDSEGHSEDSDTQSVSAQGKAGPHQQ-- 2070
S S+ + + +S + ++ +S S H+ S S + QG++ Q
Sbjct: 1781 SPGSTETTLLPDNTTASGLLEASTPVHS----STGSPHTTLSPAGSTTRQGESTTFQSWP 1836
Query: 2071 SHKESARGQSGESSGRSGSFLYQVSTHEQSESTHGQSAPSTGGRQGSHYDQAQDSSRHSA 2130
S K++ +S + + +TH ++ +T GR + ++ HS+
Sbjct: 1837 SSKDTMPAPPTTTSAFVELSTTSHGSPSSTPTTHFSASSTTLGR------SEESTTVHSS 1890
Query: 2131 SQEGQDTIRGHPGPSRGGRQGSHQEQSVDRSGHSGSHHSH----TTSQGRSDASRGQSGS 2186
T P P+R G +E + S + H +T+ GRS+ SR S
Sbjct: 1891 PVATATT----PSPARSTTSGLVEESTAYHSSPGSTQTMHFPESSTASGRSEESRTSHSS 1946
Query: 2187 R----SASRKTYDKEQSGDGSRHSGSHHHEASSWADSSRHSLVGQGQSSGPRTSRPRGSS 2242
S+ T S HS + + DSS S + ++ + G+
Sbjct: 1947 TTHTISSPPSTTSALVEEPTSYHSSPGSTATTHFPDSSTTSGRSEESTASHSSQDATGTI 2006
Query: 2243 V----SQDSDSEGHSEDSERRSGSASRNHHGSAQEQSRDGSRHPRSHHEDRA-GHGHSAE 2297
V S S G S S SGS + + H R+ S
Sbjct: 2007 VLPARSTTSVLLGESTTSPISSGSMETTALPGSTTTPGLSEKSTTFHSSPRSPATTLSPA 2066
Query: 2298 SSRQSGTHHAENSSGGQAASSHEQARSSAGERHGSHHQQSADSSRHSGIGHGQASSAVRD 2357
S+ SG +S + S+H A + G SRHS H S
Sbjct: 2067 STTSSGVSEESTTSHSRPGSTHTTAFPDSTTTPG--------LSRHSTTSHSSPGSTDTT 2118
Query: 2358 --SGHRGSSGSQASDSEGHSEDSDTQSVSAHGQAGPHQQSHQESTRGRSAGRS------- 2408
+SG + HS T + + G + +T S G +
Sbjct: 2119 LLPASTTTSGPSQESTTSHSSPGSTDTALSPGSTTALSFGQESTTFHSSPGSTHTTLFPD 2178
Query: 2409 GRSGSFLYQVSTHEQSESAHGRT------GTSTGGRQGSHHKQARDSSRHSTSQ------ 2456
+ S + + ST S + RT TS G + S Q +S H+T
Sbjct: 2179 STTSSGIVEASTRVHSSTGSPRTTLSPASSTSPGLQGESTAFQTHPASTHTTPSPPSTAT 2238
Query: 2457 ---EGQDTIHGHPGSSSGGRQGSHYEQLVDRSGHS-----------------GSHHSHTT 2496
E T H PGS+ +H+ SGHS S HS T+
Sbjct: 2239 APVEESTTYHRSPGST----PTTHFPASSTTSGHSEKSTIFHSSPDASGTTPSSAHSTTS 2294
Query: 2497 SQGRSDASHGHSGSRSASRQTRNDEQSGDGSRHSGSRHHEASSRADSSGHSQVGQGQSEG 2556
+G S S GS + + G + S S S G E
Sbjct: 2295 GRGESTTSRISPGSTEITTLPGSTTTPGLSEASTTFYSSPRSPTTTLSPASMTSLGVGEE 2354
Query: 2557 PRTSRNW-GSSFSQDSDSQGHSEDSERWSGSASRNHHGSAQEQL---------------- 2599
TSR+ GS+ S S + + S + + GS + +
Sbjct: 2355 STTSRSQPGSTHSTVSPASTTTPGLSEESTTVYSSSPGSTETTVFPRTPTTSVRGEEPTT 2414
Query: 2600 ---RDGSRHPRSHQEDRAGHGHSADS--------SRQSGTRHTQT------------SSG 2636
R S H ED G + +S S Q+G T T SS
Sbjct: 2415 FHSRPASTHTTLFTEDSTTSGLTEESTAFPGSPASTQTGLPATLTTADLGEESTTFPSSS 2474
Query: 2637 GQAASSHEQARSSAGERHG--SHHQQSADSSRHSGIGHGQASSAVRDSGHRGYSGSQASD 2694
G ++ ARS+ G + + S S+ + + + ++ + Y+ ++ D
Sbjct: 2475 GSTGTTLSPARSTTSGLVGESTPSRLSPSSTETTTLPGSPTTPSLSEKSTTFYTSPRSPD 2534
Query: 2695 ---------NEGHSEDSDTQSVSAHGQAGS-HQQSHQESARGRSGETSGHSGSFLYQVST 2744
+ G SE+S T +H Q GS H + +S + S HS +
Sbjct: 2535 ATLSPATTTSSGVSEESST----SHSQPGSTHTTAFPDST--TTPGLSRHSTT------- 2581
Query: 2745 HEQSESSHGWTGPSTRGRQGSRHEQAQDSSRHSASQDGQDTIRGHPGSSRGGRQGYHHE- 2803
S SS G T + + +Q+S+ +S DT PGS+ G
Sbjct: 2582 ---SHSSPGSTDTTLLPASTTTSGPSQESTTSHSSPGSTDTALS-PGSTTALSFGQESTT 2637
Query: 2804 -HSVDSSGHSGSHHSHTTSQGRSDASRGQSGSRSASRTTRNEEQS---GDGSRHSGSRHH 2859
HS S H+ TTS G +AS S + RTT + S G + + H
Sbjct: 2638 FHSSPGSTHTTLFPDSTTSSGIVEASTRVHSSTGSPRTTLSPASSTSPGLQGESTTFQTH 2697
Query: 2860 EASTHADISRHSQAVQGQSEGSRRSRRQGSSVS----QDSDSEGHSEDSERWSGSASRNH 2915
ASTH S S A E + R GS+ + S + GHSE S + S +
Sbjct: 2698 PASTHTTPSPPSTATAPVEESTTYHRSPGSTPTTHFPASSTTSGHSEKSTIFHSSPDAS- 2756
Query: 2916 HGSAQEQLRDGSRHPRSHQEDRAGHGHSADSSRQSGTRHTQTSSGGQAASSHEQARSSAG 2975
P S +G G S S G+ T G +A ++
Sbjct: 2757 -----------GTTPSSAHSTTSGRGESTTSRISPGSTEITTLPGSTTTPGLSEASTTFY 2805
Query: 2976 ERHGSHHQQSADSSRHS-GIGHGQASSAVRDSGHRGYSGSQASDNEGHSEDSDTQSVSAH 3034
S + +S S G+G +S + ++ G SE+S T S+
Sbjct: 2806 SSPRSPTTTLSPASMTSLGVGEESTTSRSQPGSTHSTVSPASTTTPGLSEESTTVYSSSP 2865
Query: 3035 GQAGS--HQQSHQESARGRSGETSGHSGSFLYQVSTHEQSESSHGWTGPSTRGRQGSRHE 3092
G + +S S RG T+ HS + + ++ G T ST
Sbjct: 2866 GSTETTVFPRSTTTSVRGEE-PTTFHSRPASTHTTLFTEDSTTSGLTEESTAFPGSPAST 2924
Query: 3093 QAQDSSRHSASQYGQDTIRGHPGSSRGGRQGYHHEHSVDSSGHSGSHHSHTTS--QGRSD 3150
Q + + + G+++ P SS S+G + S TTS G S
Sbjct: 2925 QTGLPATLTTADLGEESTT-FPSSS-------------GSTGTTLSPARSTTSGLVGEST 2970
Query: 3151 ASRGQSGSRSASRTTRNEEQSGDSSRHSVSRHHEASTHADISRHSQAVQGQSEGSRRSRR 3210
SR S + + S + + S A +S + G SE S S
Sbjct: 2971 PSRLSPSSTETTTLPGSPTTPSLSEKSTTFYTSPRSPDATLSPATTTSSGVSEESSTSHS 3030
Query: 3211 QGSSVSQDSDSEGHSEDSERWSGSASRNHRGSVQEQSRHGSRHPRSHHEDRAGHGHS--- 3267
Q S + + + +AS + +GS + GS S + S
Sbjct: 3031 QPGSTHTTAFPDSTTTSGLSQEPTASHSSQGSTEATLSPGSTTASSLGQQSTTFHSSPGD 3090
Query: 3268 ------ADRSRQSGTRHAETSSGGQAASSH-----EQARSSPGERHGSRHQQSADSSRHS 3316
D + SG A T + S H + S+ + + Q SS +
Sbjct: 3091 TETTLLPDDTITSGLVEASTPTHSSTGSLHTTLTPASSTSAGLQEESTTFQSWPSSSDTT 3150
Query: 3317 GIPRGQASSAVRDSRHWGSSGSQ--------ASDSEGHSEESDTQSVS------------ 3356
P G ++ V S + S S +S + G SEES T S
Sbjct: 3151 PSPPGTTAAPVEVSTTYHSRPSSTPTTHFSASSTTLGRSEESTTVHSSPGATGTALFPTR 3210
Query: 3357 -------GHGQAGPHQQSHQES----ARDRSGGRSGRSGSFLYQVSTHEQSESAHGRTRT 3405
G P E+ + G S +S +F S + + T
Sbjct: 3211 SATSVLVGEPTTSPISSGSTETTALPGSTTTAGLSEKSTTF--YSSPRSPDTTLSPASTT 3268
Query: 3406 STGRRQGSHHEQARDSSRHSASQEGQDTIRGHPGSSRRGRQGSHYEQSVDRSGHSGSHHS 3465
S+G + S +R S H+ + G T+ PG S+ S D + G S
Sbjct: 3269 SSGVSEESTTSHSRPGSTHTTAFPGSTTM---PGVSQESTASHSSPGSTDTTLSPG---S 3322
Query: 3466 HTTSQGRSDASRGQSGSRSASRQTRNDEQSGDG--------SRHSWSHHHEASTQADSSR 3517
T S +++ SG S D + G + S H S ++R
Sbjct: 3323 TTASSLGPESTTFHSGPGSTETTLLPDNTTASGLLEASTPVHSSTGSPHTTLSPAGSTTR 3382
Query: 3518 HSQSGQGQS------AGPRTSRNQGSSVSQDSDSQGHSEDSERWSGSASRNHRGSAQEQS 3571
+S QS P + V + S G + SAS G ++E +
Sbjct: 3383 QGESTTFQSWPNSKDTTPAPPTTTSAFVELSTTSHGSPSSTPTTHFSASSTTLGRSEEST 3442
Query: 3572 RDGSRHPTSHHEDRAGHGHSAESSRQSGTHHAENSSGGQAASSHEQARSSAGERHGSHHQ 3631
S + ++ +S T+H SS G + H + R G
Sbjct: 3443 TVHSSPVATATTPSPARSTTSGLVEESTTYH---SSPGSTQTMHFPESDTTSGR-GEEST 3498
Query: 3632 QSADSSRHSGIGHGQASSAV--RDSGHRGSSGSQASDSEGHSEDSDTQSVSAHGQAGPHQ 3689
S S+ H+ +SA+ + + S GS A+ H DS T S + H
Sbjct: 3499 TSHSSTTHTISSAPSTTSALVEEPTSYHSSPGSTATT---HFPDSSTTSGRSEESTASHS 3555
Query: 3690 QSHQESTRGRSAGRSGRSGSFLYQVSTHEQSESAHGRAGPSTGGRQGSRHEQARDSSRHS 3749
T A RS S ++ S S A P + G + ++ HS
Sbjct: 3556 SQDATGTIVLPA-RSTTSVLLGESTTSPISSGSMETTALPGSTTTPGL---SEKSTTFHS 3611
Query: 3750 ASQEGQDTIRGHPGSRRGGRQGSYHEQSVDRSGHSGSHHSHTTSQG---RSDASHGQSGS 3806
+ + T+ + G + S S S H+ + TT+ G S SH GS
Sbjct: 3612 SPRSPATTLSPASTTSSGVSEESTTSHSRPGSTHTTAFPDSTTTPGLSRHSTTSHSSPGS 3671
Query: 3807 RSASRETRNEEQSGDGSRHSGSRHHEASTQADSSRHSQSGQGESAGSRRSRRQGSSVSQD 3866
+ + S GS + H +S D++ S S G + S S
Sbjct: 3672 TDTTLLPASTTTS--GSSQESTTSHSSSGSTDTALSPGSTTALSFGQESTTFHSSPGSTH 3729
Query: 3867 SDSEAYPEDSERRSESASRNHH--GSSREQ-SRDGSRHPGSSHRDTASHVQSSPVQSDSS 3923
+ S E+++R H GS R S S PG TA Q+ P + ++
Sbjct: 3730 TTLFPDSTTSSGIVEASTRVHSSTGSPRTTLSPASSTSPGLQGESTA--FQTHPASTHTT 3787
Query: 3924 TAKEHGHFSSLSQDSAYHSGIQSRGSPHSSSSYHYQSEGT 3963
+ + + + + YH SP S+ + H+ + T
Sbjct: 3788 PSPPSTATAPVEESTTYHR------SPGSTPTTHFPASST 3821
Score = 190 bits (483), Expect = 2e-47
Identities = 789/3699 (21%), Positives = 1221/3699 (33%), Gaps = 468/3699 (12%)
Query: 237 YTIQDEAYDTTDSLLEENKIYERSRSSDGKSSSQVNRSRHENTSQVPLQESRTRKRRGSR 296
+T A T+ L EE+ ++ SS + S T+ P++ S T R S
Sbjct: 1563 HTTLTPASSTSAGLQEESTTFQSWPSSSDTTPSP------PGTTAAPVEVSTTYHSRPSS 1616
Query: 297 V-----SQDRDSEGHSEDSERHSGSASRNHHGSAWEQSRDGSRHPRSHDEDRASHGHSAD 351
S + G SE+S S G+A +R + G
Sbjct: 1617 TPTTHFSASSTTLGRSEESTTVHSSPGAT--GTALFPTRSATS---------VLVGEPTT 1665
Query: 352 SSRQSGTRHAETSSRGQTASSHEQARSSPGERHGSGHQQSADSSRHSATGRGQASSAVSD 411
S SG+ T+ G T ++ +S+ + S S S T G + + +
Sbjct: 1666 SPISSGSTET-TALPGSTTTAGLSEKSTTF--YSSPRSPDTTLSPASTTSSGVSEESTTS 1722
Query: 412 RGHRGSSGSQASDSEGHSENSDTQSVSGHGKAGLRQQ--SHQESTRGRSGERSGRSGSSL 469
GS+ + A +S + H G S +T G S SS
Sbjct: 1723 HSRPGSTHTTAFPGSTTMPGVSQESTASHSSPGSTDTTLSPGSTTASSLGPESTTFHSSP 1782
Query: 470 YQVSTHEQPDSAHGRTGTSTGGRQGSHHEQARDSSRHSASQEGQDTIRGHPGSSRGGRQG 529
T PD+ T++G + S + S H+ T R ++
Sbjct: 1783 GSTETTLLPDNT-----TASGLLEASTPVHSSTGSPHTTLSPAGSTTRQGESTTFQSWPS 1837
Query: 530 SHHEQSVNRSGHSGSHHSHTTSQGRSDASHGQSGSRSASRQTRNEEQSGDGTRHSGSRHH 589
S + S TTS G ++ S S++ R+EE + T HS
Sbjct: 1838 SKDTMPAPPTTTSAFVELSTTSHGSPSSTPTTHFSASSTTLGRSEEST---TVHSSPVAT 1894
Query: 590 EAS-SQADSSRHSQVGQGQSSGPRTSRNQGSSVSQDSDSQGHSEDSERWSGSASRNHHGS 648
+ S A S+ V + + Q + S + G SE+S R S S++ + S
Sbjct: 1895 ATTPSPARSTTSGLVEESTAYHSSPGSTQTMHFPESSTASGRSEES-RTSHSSTTHTISS 1953
Query: 649 AQEQSRDGSRHPRSHHEDRAGHG--HSADSSRKSGTRHTQNSS-SGQAASSHE--QARSS 703
+ P S+H H DSS SG +S S Q A+ ARS+
Sbjct: 1954 PPSTTSALVEEPTSYHSSPGSTATTHFPDSSTTSGRSEESTASHSSQDATGTIVLPARST 2013
Query: 704 A----GERHGSRHQLQSADSSRHSGT----GHGQASSAVRDSGHRGSS--GSQATDSEGH 753
GE S S +++ G+ G + S+ S ++ +T S G
Sbjct: 2014 TSVLLGESTTSPISSGSMETTALPGSTTTPGLSEKSTTFHSSPRSPATTLSPASTTSSGV 2073
Query: 754 SEDSDTQSVSGHGQAGHHQQSHQESARDRSGERSRRSGSFLYQVSTHKQSESSHGWTGPS 813
SE+S T H + G +H + D + G + ++H S+ P+
Sbjct: 2074 SEESTTS----HSRPG---STHTTAFPDST----TTPGLSRHSTTSHSSPGSTDTTLLPA 2122
Query: 814 TGVRQGSHHEQARDNSRHSASQDGQDTIRGHPGSSRRGRQGSHHE--QSVDRSGHSGSHH 871
+ G E S S S G PGS+ G S S H+
Sbjct: 2123 STTTSGPSQE-----STTSHSSPGSTDTALSPGSTTALSFGQESTTFHSSPGSTHTTLFP 2177
Query: 872 SHTTSQGRSDASRGQSGSRSASRTTRNEEQSRDGSRHSGS---RHHEASSHADISRHSQA 928
TTS G +AS S + RTT + S S + H AS+H S S A
Sbjct: 2178 DSTTSSGIVEASTRVHSSTGSPRTTLSPASSTSPGLQGESTAFQTHPASTHTTPSPPSTA 2237
Query: 929 GQGQSEGSRTSRRQGSSVSQ----DSDSEGHSEDSERWSGSASRNHRGSAQEQSRHGSRH 984
E + R GS+ + S + GHSE S + S +
Sbjct: 2238 TAPVEESTTYHRSPGSTPTTHFPASSTTSGHSEKSTIFHSSPDAS------------GTT 2285
Query: 985 PRSHHEDRAGHGHSADSSRQSGTPHAETSSGGQAASSHEQARSSPGERHGSRHQQSADSS 1044
P S H +G G S S G+ T G + ++PG S S+ S
Sbjct: 2286 PSSAHSTTSGRGESTTSRISPGSTEITTLPG---------STTTPGLSEASTTFYSSPRS 2336
Query: 1045 RHSGIPRRQASSAVRDSGHWGSSGSQASDSEGHSEESDT---QSVSGHGQDGPHQQSHQE 1101
P S A + S G EES T Q S H P +
Sbjct: 2337 -----PTTTLSPA-------------SMTSLGVGEESTTSRSQPGSTHSTVSPASTTTPG 2378
Query: 1102 SARDWSGGRSGRSGSFIYQVSTHEQSESAHGRTRTSTGRRQGSHHEQ--ARDSSRHSASQ 1159
+ + + S GS V + S G T+ R S H DS+ ++
Sbjct: 2379 LSEESTTVYSSSPGSTETTVFPRTPTTSVRGEEPTTFHSRPASTHTTLFTEDSTTSGLTE 2438
Query: 1160 EGQDTIRAHPGSRRGGRQG--------SHHEQSVDRSGHSGSHHSHTTSQGRSDASHGQS 1211
E A PGS + G E+S SGS + T S RS S G
Sbjct: 2439 EST----AFPGSPASTQTGLPATLTTADLGEESTTFPSSSGSTGT-TLSPARSTTS-GLV 2492
Query: 1212 GSRSASRQTRKDKQSGD--GSRHSGSRHHEAASWADSSRHSQVGQEQSSGSRTSRHQGSS 1269
G + SR + ++ GS + S ++ ++ S R ++ + + + SS
Sbjct: 2493 GESTPSRLSPSSTETTTLPGSPTTPSLSEKSTTFYTSPRSPDATLSPATTTSSGVSEESS 2552
Query: 1270 VSQDSDSERHSD---DSERLSGSASRNHHGSSREQSRDGSRHP------GFHQEDRASHG 1320
S H+ DS G + + S S D + P G QE SH
Sbjct: 2553 TSHSQPGSTHTTAFPDSTTTPGLSRHSTTSHSSPGSTDTTLLPASTTTSGPSQESTTSHS 2612
Query: 1321 HSADSSRQSGTHHTESSSHGQAVSSHEQARSSPGERHGSRHQQSADSSR--------HSG 1372
+ T + S GQ ++ SSPG H + S SS HS
Sbjct: 2613 SPGSTDTALSPGSTTALSFGQESTTFH---SSPGSTHTTLFPDSTTSSGIVEASTRVHSS 2669
Query: 1373 IGHRQASSAVRDSGHRGSSGSQVTNSEGHSEDSDTQSVSAHGQAGPHQQSHKESARGQ-- 1430
G + + + S G G T + T S + A + + + G
Sbjct: 2670 TGSPRTTLSPASSTSPGLQGESTTFQTHPASTHTTPSPPSTATAPVEESTTYHRSPGSTP 2729
Query: 1431 ------SGESSGRSRSFLYQVSSHEQSESTHGQTAPSTGGRQGSRHEQARNSSRHSASQD 1484
S +SG S SS + S +T +T GR S + S +
Sbjct: 2730 TTHFPASSTTSGHSEKSTIFHSSPDASGTTPSSAHSTTSGRGESTTSRISPGSTEITTLP 2789
Query: 1485 GQDTIRG-------------------HPGS--SRGGRQGSYHEQSVDRSGHSGYHHSHTT 1523
G T G P S S G + S +S S HS + TT
Sbjct: 2790 GSTTTPGLSEASTTFYSSPRSPTTTLSPASMTSLGVGEESTTSRSQPGSTHSTVSPASTT 2849
Query: 1524 PQGRSD-------ASHGQSG----PRSASRQTRNEEQSGDGSRHSGSR---HHEPSTRAG 1569
G S+ +S G + PRS + R EE + SR + + E ST +G
Sbjct: 2850 TPGLSEESTTVYSSSPGSTETTVFPRSTTTSVRGEEPTTFHSRPASTHTTLFTEDSTTSG 2909
Query: 1570 SSRHSQVGQGESAGSKTSR----------RQGSSVSQDRDSEGHSEDSERRSESA----- 1614
+ S G A ++T + ++ S G + R + S
Sbjct: 2910 LTEESTAFPGSPASTQTGLPATLTTADLGEESTTFPSSSGSTGTTLSPARSTTSGLVGES 2969
Query: 1615 --SRNHYGSAREQSRHGSRNPRSHQEDRASHGHSAESSRQSGTRHAETSSGGQAASSQEQ 1672
SR S + GS S E + S S + + TSSG SS
Sbjct: 2970 TPSRLSPSSTETTTLPGSPTTPSLSEKSTTFYTSPRSPDATLSPATTTSSGVSEESST-- 3027
Query: 1673 ARSSPGERHGSRHQQSADSSTDSGTGRRQDSSVVGDSGNRG--SSGSQASDSEG------ 1724
+ S PG H + DS+T SG + +S S GS + S G
Sbjct: 3028 SHSQPGSTHTTAFP---DSTTTSGLSQEPTASHSSQGSTEATLSPGSTTASSLGQQSTTF 3084
Query: 1725 HSEESDTQSV--------SAHGQAGPHQQSHQESTRGQSGERSGRSGSFLYQVSTHEQSE 1776
HS DT++ S +A S S S S L + ST QS
Sbjct: 3085 HSSPGDTETTLLPDDTITSGLVEASTPTHSSTGSLHTTLTPASSTSAG-LQEESTTFQSW 3143
Query: 1777 SAHGRTGPSTGGRQRSRHE-----QARDSS----RHSASQ------EGQDTIRGHPGSSR 1821
+ T PS G + E +R SS SAS E T+ PG++
Sbjct: 3144 PSSSDTTPSPPGTTAAPVEVSTTYHSRPSSTPTTHFSASSTTLGRSEESTTVHSSPGATG 3203
Query: 1822 GGRQGSHYEQSV----DSSGHSGSHHSHTTSQERSDVSRGQSGSRSVSRQTRNEKQSGDG 1877
+ SV ++ S + TT+ S + G S S + +S D
Sbjct: 3204 TALFPTRSATSVLVGEPTTSPISSGSTETTALPGSTTTAGLSEK---STTFYSSPRSPDT 3260
Query: 1878 SRHSGSRHHEASSRADSSRHSQVGQGQSSG-PRTSRNQG-SSVSQDSDSQGHSEDSERWS 1935
+ S S ++ HS+ G ++ P ++ G S S S S S D+
Sbjct: 3261 TLSPASTTSSGVSEESTTSHSRPGSTHTTAFPGSTTMPGVSQESTASHSSPGSTDTTLSP 3320
Query: 1936 GSASRNHLGSAWEQSRDGSRHPGSHHEDRAGHGHSADSSRQSGTRHTESSSRGQAASSHE 1995
GS + + LG G PGS D++ SG + S H
Sbjct: 3321 GSTTASSLGPESTTFHSG---PGSTETTLL-----PDNTTASGLLEASTPVHSSTGSPHT 3372
Query: 1996 QARSSAGE--RHGSHHQLQSADSSRHSGIGHGQASSA---VRDSGHRGYSG------SQA 2044
S AG R G QS +S+ + +SA + + H S S +
Sbjct: 3373 TL-SPAGSTTRQGESTTFQSWPNSKDTTPAPPTTTSAFVELSTTSHGSPSSTPTTHFSAS 3431
Query: 2045 SDSEGHSEDSDTQSVSAQGKAGPHQQSHKESARGQSGESSGRSGSFLYQVSTHEQSESTH 2104
S + G SE+S T S A + ++ ++ S Q +S++T
Sbjct: 3432 STTLGRSEESTTVHSSPVATATTPSPARSTTSGLVEESTTYHSSPGSTQTMHFPESDTTS 3491
Query: 2105 GQSAPSTGGRQGSHYDQAQDSSRHSASQEGQDTIRGHPG-------PSRGGRQGSHQEQS 2157
G+ ST + + + S SA E + PG P G +E +
Sbjct: 3492 GRGEESTTSHSSTTHTISSAPSTTSALVEEPTSYHSSPGSTATTHFPDSSTTSGRSEEST 3551
Query: 2158 VDRSGHSGSHH-----SHTTSQ--GRSDASRGQSGSRSASRKTYDKEQSGDGSRHSGSHH 2210
S + TTS G S S SGS + G + + H
Sbjct: 3552 ASHSSQDATGTIVLPARSTTSVLLGESTTSPISSGSMETTALPGSTTTPGLSEKSTTFHS 3611
Query: 2211 HEASSWADSSRHSLVGQGQSSGPRTSRPRGSSVSQDSDSEGHSEDSERRSGSASRNHHGS 2270
S S S G S TS R S + + + R + S + GS
Sbjct: 3612 SPRSPATTLSPASTTSSGVSEESTTSHSRPGSTHTTAFPDSTTTPGLSRHSTTSHSSPGS 3671
Query: 2271 AQEQSRDGSRHPRSHHEDRAGHGHSAESSRQSGTHHAENSSGGQAASSHEQARSSAGERH 2330
S ++ S S SG+ S G A S Q ++
Sbjct: 3672 TDTTLLPASTTTSGSSQE------STTSHSSSGSTDTALSPGSTTALSFGQESTTFHSSP 3725
Query: 2331 GSHHQQS-ADSSRHSGIGHGQASSAVRDS-GHRGSSGSQASDS----EGHSEDSDTQSVS 2384
GS H DS+ SGI +AS+ V S G ++ S AS + +G S T S
Sbjct: 3726 GSTHTTLFPDSTTSSGIV--EASTRVHSSTGSPRTTLSPASSTSPGLQGESTAFQTHPAS 3783
Query: 2385 AHGQAGPHQQS----HQESTRGRSAGR------------SGRSGSFLYQVSTHEQSESAH 2428
H P + + +T RS G SG S S+ + S +
Sbjct: 3784 THTTPSPPSTATAPVEESTTYHRSPGSTPTTHFPASSTTSGHSEKSTIFHSSPDASGTTP 3843
Query: 2429 GRTGTSTGGRQGSHHKQARDSSRHSTSQEGQDTIHGHPGSSSG--GRQGSHYEQLVDRSG 2486
++T GR S + S T+ G T G +S+ S L S
Sbjct: 3844 SSAHSTTSGRGESTTSRISPGSTEITTLPGSTTTPGLSEASTTFYSSPRSPTTTLSPASM 3903
Query: 2487 HS-GSHHSHTTSQGRSDASHGHSGSRSASRQTRNDEQSGDGSRHSGSRHHEASSRADSSG 2545
S G TTS+ + ++H S + ++E + S GS R+ ++
Sbjct: 3904 TSLGVGEESTTSRSQPGSTHSTVSPASTTTPGLSEESTTVYSSSPGSTETTVFPRSTTTS 3963
Query: 2546 HSQVGQGQSEGPRTSRNWGSS-----FSQDSDSQGHSEDSERWSGSASRNHHGSAQEQLR 2600
+ E P T + +S F++DS + G +E+S + GS
Sbjct: 3964 VRR------EEPTTFHSRPASTHTTLFTEDSTTSGLTEESTAFPGS-------------- 4003
Query: 2601 DGSRHPRSHQEDRAGHGHSADSSRQSGTRHTQTSSGGQAASSHEQARSS-AGERHGSHHQ 2659
P S Q +AD +S T + + S G S S GE S +
Sbjct: 4004 -----PASTQTGLPATLTTADLGEESTTFPSSSGSTGTKLSPARSTTSGLVGESTPS--R 4056
Query: 2660 QSADSSRHSGIGHGQASSAVRDSGHRGYSGSQASD---------NEGHSEDSDTQSVSAH 2710
S S+ + + + ++ + Y+ ++ D + G SE+S T +H
Sbjct: 4057 LSPSSTETTTLPGSPTTPSLSEKSTTFYTSPRSPDATLSPATTTSSGVSEESST----SH 4112
Query: 2711 GQAGSHQQSHQESARGRSGETSGHSGSFLYQVSTHEQSESSHGWTGPSTRGRQGSRHEQA 2770
Q GS + + SG + + S Q ST ++ S G T S+ G+Q +
Sbjct: 4113 SQPGSTHTTAFPDSTTTSGLSQEPTTSHSSQGST--EATLSPGSTTASSLGQQSTTF--- 4167
Query: 2771 QDSSRHSASQDGQDTIRGHPGSSRGGRQGYHHEHSVDSSGHSGSHHSHTTSQGRSDASRG 2830
HS+ D + T+ + G + HS S H+ + +TS G + S
Sbjct: 4168 -----HSSPGDTETTLLPDDTITSGLVEASTPTHSSTGSLHTTLTPASSTSTGLQEESTT 4222
Query: 2831 QSGSRSASRTTRNEEQSGDGSRHSGSRHHE--ASTHADISRHSQAVQGQSEGSRRSRRQG 2888
S+S TT + + + +H +ST S G+SE S
Sbjct: 4223 FQSWPSSSDTTPSPPSTTAVPVEVSTTYHSRPSSTPTTHFSASSTTLGRSEESTTVHSSP 4282
Query: 2889 SSVSQDSDSEGHSEDSERWSGSASRNHHGSAQEQLRDGSRHPRSHQEDRAGHGHSADSSR 2948
+ + + S GS + GS E ++ +S+ S
Sbjct: 4283 GATGTALFPTRSATSVLVGEPTTSPISSGSTETTALPGSTTTAGLSE-KSTTFYSSPRSP 4341
Query: 2949 QSGTRHTQTSSGGQAASSHEQARSSAGERHGSHHQQSADSSRHSGIGHGQASSAVRDSGH 3008
+ T+S G + S +++ R GS H + SS G Q S+A S
Sbjct: 4342 DTTLSPASTTSSGVSEES-----TTSHSRPGSMHTTAFPSSTTMP-GVSQESTASHSSP- 4394
Query: 3009 RGYSGSQASDNEGHSEDSDTQSVSAHGQAGSHQQSHQESARGRSGETSGHSGSFLYQVST 3068
G + + S + +S + H GS + + SG L + ST
Sbjct: 4395 -GSTDTTLSPGSTTASSLGPESTTFHSSPGSTETTLLPDNTTASG---------LLEAST 4444
Query: 3069 --HEQSESSHGWTGPSTRGRQGSRHEQAQDSSRHSASQYGQDTIRGHPGSSRGGRQGYHH 3126
H + S H P+ GS Q + ++ S +DT P ++ +
Sbjct: 4445 PVHSSTGSPHTTLSPA-----GSTTRQGESTTFQSWPN-SKDTTPAPPTTTSAFVELSTT 4498
Query: 3127 EHSVDSSGHSGSHHSHTTSQGRSDASRGQSGSRSASRTTRNEEQSGDSSRHSVSRHHEAS 3186
H SS + + +T+ GRS+ S S A+ TT + +S S S + +S
Sbjct: 4499 SHGSPSSTPTTHFSASSTTLGRSEESTTVHSSPVATATTPSPARSTTSGLVEESTTYHSS 4558
Query: 3187 THADISRH---SQAVQGQSEGSRRSRRQGSSVSQDSDSEGHSEDSERWS-----GSASRN 3238
+ + H S G+ E S S + + S + E S GS +
Sbjct: 4559 PGSTQTMHFPESNTTSGRGEESTTSHSSTTHTISSAPSTTSALVEEPTSYHSSPGSTATT 4618
Query: 3239 HRGSVQEQSRHGSRHPRSHH-EDRAGHGHSADRSRQSGTRHAETSSGGQAASSHEQARSS 3297
H S SH +D G RS S T+S + S A
Sbjct: 4619 HFPDSSTTSGRSEESTASHSSQDATGTIVLPARSTTSVLLGESTTSPISSGSMETTALPG 4678
Query: 3298 PGERHGSRHQQSADSSRHSGIPRGQASSAVRDSRHWGSSGSQASDSEGHSEESDTQSVSG 3357
G + + S S P + H+ +S S + G SEES T S
Sbjct: 4679 STTTPGLSEKSTTFHSSPSSTP----------TTHFSAS----STTLGRSEESTTVHSSP 4724
Query: 3358 HGQAGPHQQSHQESARDRSGGRSGRSGSFLYQVSTHEQSESAHGRTRTSTGRRQGSHHEQ 3417
A + ++ + S Q +S +A GR+ S + H
Sbjct: 4725 VATATTPSPARSTTSGLVEESTAYHSSPGSTQTMHFPESSTASGRSEESRTSHSSTTHTI 4784
Query: 3418 ARDSSRHSASQEGQDTIRGHPGSSRRGRQGSHYEQSVDRSGHS----GSHHS-------- 3465
+ S SA E + PGS +H+ +S SG S SH S
Sbjct: 4785 SSPPSTTSALVEEPTSYHSSPGSIAT----THFPESSTTSGRSEESTASHSSPDTNGITP 4840
Query: 3466 ---HTTSQGRSDASR------GQSGSRSASRQTRNDEQSGDGSRHSWSHHHEAS-TQADS 3515
H T+ GR S G + AS T + +S S + + + A
Sbjct: 4841 LPAHFTTSGRIAESTTFYISPGSMETTLASTATTPGLSAKSTILYSSSRSPDQTLSPASM 4900
Query: 3516 SRHSQSGQGQSAGPRTSRNQGSSVSQDSDSQGHSEDSERW---SGSASRNHRGSAQEQSR 3572
+ S SG+ S + ++ + + G S++S + GS + S
Sbjct: 4901 TSSSISGEPTSLYSQAESTHTTAFPASTTTSGLSQESTTFHSKPGSTETTLSPGSITTSS 4960
Query: 3573 DGSRHPTSHHEDRAGHGHSAESSRQSGTHHAENSSGGQAASSHEQARSSAGERHGSHHQQ 3632
T H + + + +S E+++ + S E S H QQ
Sbjct: 4961 FAQEFTTPHSQPGSALSTVSPASTTVPGLSEESTTFYSSPGSTETTAFSHSNTMSIHSQQ 5020
Query: 3633 SADSSRHSGIGHG--QASSAVRDSGHRGSSGSQASDSEG 3669
S G H A+ D G ++ +SD+ G
Sbjct: 5021 STPFPDSPGFTHTVLPATLTTTDIGQESTAFHSSSDATG 5059
Score = 160 bits (404), Expect = 3e-38
Identities = 691/3281 (21%), Positives = 1065/3281 (32%), Gaps = 452/3281 (13%)
Query: 229 QSGHIATYYTIQDEAYDTTDSLLEENKIYERSRSSDGKS----SSQVNRSRHENTSQVPL 284
++ H +T +TI TT +L+EE Y S S + SS + E+T+
Sbjct: 1941 RTSHSSTTHTISSPP-STTSALVEEPTSYHSSPGSTATTHFPDSSTTSGRSEESTASHSS 1999
Query: 285 QESRTRKRRGSRVSQDRDSE----GHSEDSERHSGSASRNHHGSAWEQSRDGSRHPRSHD 340
Q++ G+ V R + G S S SGS + + H
Sbjct: 2000 QDAT-----GTIVLPARSTTSVLLGESTTSPISSGSMETTALPGSTTTPGLSEKSTTFHS 2054
Query: 341 EDRA-SHGHSADSSRQSGTRHAETSSRGQTASSHEQA----RSSPG-ERHGSGHQQSADS 394
R+ + S S+ SG T+S + S+H A ++PG RH + S S
Sbjct: 2055 SPRSPATTLSPASTTSSGVSEESTTSHSRPGSTHTTAFPDSTTTPGLSRHSTTSHSSPGS 2114
Query: 395 SRH-----SATGRGQASSAVSDRGHRGSSGSQASDSEGHSENSDTQSVSGHGKAGLRQQS 449
+ S T G + + + GS+ + S + + +S + H G +
Sbjct: 2115 TDTTLLPASTTTSGPSQESTTSHSSPGSTDTALSPGSTTALSFGQESTTFHSSPGSTHTT 2174
Query: 450 HQESTRGRSG--ERSGRSGSSLYQVSTHEQPDSAH--GRTGTSTGGRQ--GSHHEQARDS 503
+ SG E S R SS T P S+ G G ST + S H
Sbjct: 2175 LFPDSTTSSGIVEASTRVHSSTGSPRTTLSPASSTSPGLQGESTAFQTHPASTHTTPSPP 2234
Query: 504 SRHSASQEGQDTIRGHPGSSRGGRQGSHHEQSVNRSGHSGSH---HSHTTSQGRSDAS-H 559
S +A E T PGS+ +H S SGHS HS + G + +S H
Sbjct: 2235 STATAPVEESTTYHRSPGST----PTTHFPASSTTSGHSEKSTIFHSSPDASGTTPSSAH 2290
Query: 560 GQSGSRSASRQTRNEEQSGDGTRHSGSRHHEASSQADSSRHSQVGQGQSS-GPRTSRNQG 618
+ R S +R S + T GS S+A ++ +S ++ P + + G
Sbjct: 2291 STTSGRGESTTSRISPGSTEITTLPGSTTTPGLSEASTTFYSSPRSPTTTLSPASMTSLG 2350
Query: 619 ----SSVSQDSDSQGHSEDSERWSGSASRNHHGSAQEQSRDGSRH----PRSHHEDRAGH 670
S+ S+ HS S + + + + S GS PR+ G
Sbjct: 2351 VGEESTTSRSQPGSTHSTVSPASTTTPGLSEESTTVYSSSPGSTETTVFPRTPTTSVRGE 2410
Query: 671 GHSADSSRKSGTRHT----QNSSSGQAASSHEQARSSAGERHGSRHQLQSADSSRHSGTG 726
+ SR + T T +++SG S S A + G L +AD S T
Sbjct: 2411 EPTTFHSRPASTHTTLFTEDSTTSGLTEESTAFPGSPASTQTGLPATLTTADLGEESTTF 2470
Query: 727 HGQASSA--VRDSGHRGSSGSQATDSEGHSEDSDTQSVSGHGQAGHHQQSHQESA----- 779
+ S +SG + S T++ + G S + +
Sbjct: 2471 PSSSGSTGTTLSPARSTTSGLVGESTPSRLSPSSTETTTLPGSPTTPSLSEKSTTFYTSP 2530
Query: 780 ----RDRSGERSRRSGSFLYQVSTHKQSESSHGWTGPSTGVRQG-SHHEQARDNSRHSA- 833
S + SG ++H Q S+H P + G S H +S S
Sbjct: 2531 RSPDATLSPATTTSSGVSEESSTSHSQPGSTHTTAFPDSTTTPGLSRHSTTSHSSPGSTD 2590
Query: 834 ----------SQDGQDTIRGH--PGSSRRGRQG------SHHEQSVDRSGHSGSHHS--- 872
S Q++ H PGS+ S ++S GS H+
Sbjct: 2591 TTLLPASTTTSGPSQESTTSHSSPGSTDTALSPGSTTALSFGQESTTFHSSPGSTHTTLF 2650
Query: 873 --HTTSQGRSDASRGQSGSRSASRTTRNEEQSRDGSRHSGS---RHHEASSHADISRHSQ 927
TTS G +AS S + RTT + S S + H AS+H S S
Sbjct: 2651 PDSTTSSGIVEASTRVHSSTGSPRTTLSPASSTSPGLQGESTTFQTHPASTHTTPSPPST 2710
Query: 928 AGQGQSEGSRTSRRQGSSVSQ----DSDSEGHSEDSERWSGSASRNHRGSAQEQSRHGSR 983
A E + R GS+ + S + GHSE S + S +
Sbjct: 2711 ATAPVEESTTYHRSPGSTPTTHFPASSTTSGHSEKSTIFHSSPDAS------------GT 2758
Query: 984 HPRSHHEDRAGHGHSADSSRQSGTPHAETSSGGQAASSHEQARSSPGERHGSRHQQSADS 1043
P S H +G G S S G+ T G + ++PG S S+
Sbjct: 2759 TPSSAHSTTSGRGESTTSRISPGSTEITTLPG---------STTTPGLSEASTTFYSSPR 2809
Query: 1044 SRHSGIPRRQASSAVRDSGHWGSSGSQASDSEGHSEESDT---QSVSGHGQDGPHQQSHQ 1100
S P S A + S G EES T Q S H P +
Sbjct: 2810 S-----PTTTLSPA-------------SMTSLGVGEESTTSRSQPGSTHSTVSPASTTTP 2851
Query: 1101 ESARDWSGGRSGRSGSFIYQVSTHEQSESAHGRTRTSTGRRQGSHHEQ--ARDSSRHSAS 1158
+ + + S GS V + S G T+ R S H DS+ +
Sbjct: 2852 GLSEESTTVYSSSPGSTETTVFPRSTTTSVRGEEPTTFHSRPASTHTTLFTEDSTTSGLT 2911
Query: 1159 QEGQDTIRAHPGSRRGGRQG--------SHHEQSVDRSGHSGSHHSHTTSQGRSDASHGQ 1210
+E A PGS + G E+S SGS + T S RS S G
Sbjct: 2912 EEST----AFPGSPASTQTGLPATLTTADLGEESTTFPSSSGSTGT-TLSPARSTTS-GL 2965
Query: 1211 SGSRSASRQTRKDKQSGD--GSRHSGSRHHEAASWADSSRHSQVGQEQSSGSRTSRHQGS 1268
G + SR + ++ GS + S ++ ++ S R S + TS S
Sbjct: 2966 VGESTPSRLSPSSTETTTLPGSPTTPSLSEKSTTFYTSPRSPDA--TLSPATTTS----S 3019
Query: 1269 SVSQDSDSERHSDDSERLSGSASRNHHGSSREQS-RDGSRHPGFHQEDRASHGHSADSSR 1327
VS++S S S + GS+ + D + G QE ASH +
Sbjct: 3020 GVSEES--------------STSHSQPGSTHTTAFPDSTTTSGLSQEPTASHSSQGSTEA 3065
Query: 1328 QSGTHHTESSSHGQAVSSHEQARSSPGERHGSRHQQS--------ADSSRHSGIGHRQAS 1379
T +SS GQ ++ SSPG+ + A + HS G +
Sbjct: 3066 TLSPGSTTASSLGQQSTTFH---SSPGDTETTLLPDDTITSGLVEASTPTHSSTGSLHTT 3122
Query: 1380 SAVRDSGHRGSSGSQVTNSEGHSEDSDTQSVSAHGQAGPHQQSHKESARGQSGESSGRSR 1439
S G + T + SDT A P + S +R S ++
Sbjct: 3123 LTPASSTSAGLQ-EESTTFQSWPSSSDTTPSPPGTTAAPVEVSTTYHSRPSSTPTTH--- 3178
Query: 1440 SFLYQVSSHEQSESTHGQTAPSTGGRQGSRHEQARNSSR-------HSASQDGQDTIRGH 1492
+ SS S T S+ G G+ R+++ S G
Sbjct: 3179 ---FSASSTTLGRSEESTTVHSSPGATGTALFPTRSATSVLVGEPTTSPISSGSTETTAL 3235
Query: 1493 PGSSR--GGRQGSYHEQSVDRSGH----------SGYHHSHTTPQGRSDASHGQSGPRSA 1540
PGS+ G + S S RS SG TT R ++H + P S
Sbjct: 3236 PGSTTTAGLSEKSTTFYSSPRSPDTTLSPASTTSSGVSEESTTSHSRPGSTHTTAFPGST 3295
Query: 1541 SRQTRNEEQSGDGSRHSGSRHHEPSTRAGSSRHSQVG-QGESAGSKTSRRQGSSVSQDRD 1599
+ ++E + HS + + GS+ S +G + + S + + + +
Sbjct: 3296 TMPGVSQESTAS---HSSPGSTDTTLSPGSTTASSLGPESTTFHSGPGSTETTLLPDNTT 3352
Query: 1600 SEGHSEDSERRSESASRNH--YGSAREQSRHGSRN-----PRSHQEDRASHGHSAESSRQ 1652
+ G E S S H A +R G P S A ++
Sbjct: 3353 ASGLLEASTPVHSSTGSPHTTLSPAGSTTRQGESTTFQSWPNSKDTTPAPPTTTSAFVEL 3412
Query: 1653 SGTRHAETSSGGQAASSQEQARSSPGERHGSRHQQSADSSTDSGTGRRQDSSVVGDSGNR 1712
S T H SS S E + H ++T R S +V +S
Sbjct: 3413 STTSHGSPSSTPTTHFSASSTTLGRSEESTTVHSSPVATATTPSPARSTTSGLVEESTTY 3472
Query: 1713 GSSGSQASDSEGHSEESDTQSVSAHGQAGPHQQSHQESTRGQSGERSGRSGSFLYQVSTH 1772
SS S H ESDT S G+ SH +T S S S S H
Sbjct: 3473 HSS--PGSTQTMHFPESDTTS----GRGEESTTSHSSTTHTISSAPSTTSALVEEPTSYH 3526
Query: 1773 EQSESA---HGRTGPSTGGRQRSRHEQARDSSRHSASQEGQDTIRGHPGSSRGGRQGSHY 1829
S H +T GR + +S+ +SQ+ TI S+ G
Sbjct: 3527 SSPGSTATTHFPDSSTTSGR-------SEESTASHSSQDATGTIVLPARSTTSVLLGEST 3579
Query: 1830 EQSVDSSG----------------------HSGSHHSHTTSQERSDVSRGQSGSRSVSRQ 1867
+ S HS TT S S G S + S
Sbjct: 3580 TSPISSGSMETTALPGSTTTPGLSEKSTTFHSSPRSPATTLSPASTTSSGVSEESTTSH- 3638
Query: 1868 TRNEKQSGDGSRHS----GSRHHEASSRADSSRHSQVGQGQSSG-PRTSRNQGSSV-SQD 1921
S GS H+ S SR ++ HS G ++ P ++ GSS S
Sbjct: 3639 ------SRPGSTHTTAFPDSTTTPGLSRHSTTSHSSPGSTDTTLLPASTTTSGSSQESTT 3692
Query: 1922 SDSQGHSEDSERWSGSASRNHLGSAWEQSRDGSRHPGSHHEDRAGHGHSADSSRQSGTRH 1981
S S S D+ GS + G ++S PGS H ++ ++ TR
Sbjct: 3693 SHSSSGSTDTALSPGSTTALSFG---QESTTFHSSPGSTHTTLFPDSTTSSGIVEASTR- 3748
Query: 1982 TESSSRGQAASSHEQARSSAGERHGSHHQLQSADSSRHSGIGHGQASSAVRDSG---HRG 2038
SS G ++ A S++ G Q+ +S H+ ++A + HR
Sbjct: 3749 -VHSSTGSPRTTLSPASSTSPGLQGESTAFQTHPASTHTTPSPPSTATAPVEESTTYHRS 3807
Query: 2039 YSGSQ------ASDSEGHSEDSDTQSVSAQGKAGPHQQSHKE-SARGQSGESSGRSGSFL 2091
+ +S + GHSE S S +H S RG+S S GS
Sbjct: 3808 PGSTPTTHFPASSTTSGHSEKSTIFHSSPDASGTTPSSAHSTTSGRGESTTSRISPGST- 3866
Query: 2092 YQVSTHEQSESTHGQSAPSTGGRQGSHYDQAQDSSRHSASQEGQDTIRGHPGPSRGGRQG 2151
+++T S +T G S ST + +S+ + T+ S G +
Sbjct: 3867 -EITTLPGSTTTPGLSEAST--------------TFYSSPRSPTTTLSPASMTSLGVGEE 3911
Query: 2152 SHQEQSVDRSGHSGSHHSHTTSQGRSDASRGQSGS-----------RSASRKTYDKEQSG 2200
S +S S HS + TT+ G S+ S S RS + +E +
Sbjct: 3912 STTSRSQPGSTHSTVSPASTTTPGLSEESTTVYSSSPGSTETTVFPRSTTTSVRREEPTT 3971
Query: 2201 DGSRHSGSH---HHEASSWADSSRHSLVGQGQSSGPRTSRPRG---SSVSQDSDSEGHSE 2254
SR + +H E S+ + + S G + +T P + + ++S + S
Sbjct: 3972 FHSRPASTHTTLFTEDSTTSGLTEESTAFPGSPASTQTGLPATLTTADLGEESTTFPSSS 4031
Query: 2255 DSERRSGSASRNHHGSAQEQSRDGSRHPRSHHEDRA-GHGHSAESSRQSGTHHAENSSGG 2313
S S +R+ +S P S G + S +S T + S
Sbjct: 4032 GSTGTKLSPARSTTSGLVGESTPSRLSPSSTETTTLPGSPTTPSLSEKSTTFYTSPRSPD 4091
Query: 2314 QAASSHEQARSSAGERHGSHHQQSADSSRHSGIGHGQASSAVRDSGHRGSSGSQASDSEG 2373
S S E + H Q + ++A DS +SG +
Sbjct: 4092 ATLSPATTTSSGVSEESSTSHSQPGSTH----------TTAFPDS--TTTSGLSQEPTTS 4139
Query: 2374 HSEDSDTQSVSAHGQAGPHQQSHQESTRGRSAGRSGRSGSFLYQVSTHEQSESAHGRTGT 2433
HS T++ + G Q +T S G + + + + S T
Sbjct: 4140 HSSQGSTEATLSPGSTTASSLGQQSTTFHSSPGDTETT------LLPDDTITSGLVEAST 4193
Query: 2434 STGGRQGSHHKQARDSSRHSTS-QEGQDTIHGHPGSSSGGRQGSHYEQL---VDRSGHSG 2489
T GS H +S ST QE T P SS + V + HS
Sbjct: 4194 PTHSSTGSLHTTLTPASSTSTGLQEESTTFQSWPSSSDTTPSPPSTTAVPVEVSTTYHSR 4253
Query: 2490 SHHSHTTSQGRSDASHGHSGSRSASRQTRNDEQSGDGSRHSGSRHHEASSRADSSGHSQV 2549
+ TT S + G RS T + G+ +R S S +
Sbjct: 4254 PSSTPTTHFSASSTTLG----RSEESTTVHSSPGATGTALFPTRS-ATSVLVGEPTTSPI 4308
Query: 2550 GQGQSEGPRTSRNWGSSFSQDSDSQGHSEDSERWSGSASRNHHGSAQEQLRDGSRHPRSH 2609
G +E ++ + + G SE S + S PRS
Sbjct: 4309 SSGSTET--------TALPGSTTTAGLSEKSTTFYSS-------------------PRSP 4341
Query: 2610 QEDRAGHGHSADSSRQSGTRHTQTSSGGQAASSHEQARSSAGERHGSHHQQSADSSRHSG 2669
S S+ SG T+S + S H A S+ G + +A HS
Sbjct: 4342 DTTL-----SPASTTSSGVSEESTTSHSRPGSMHTTAFPSSTTMPGVSQESTAS---HSS 4393
Query: 2670 IGHGQASSAVRDSGHRGYSGSQASDNEGHSEDSDTQSVSAHGQAGSHQQSHQESARGRSG 2729
G + + GS + + G +S + H GS + + SG
Sbjct: 4394 PGSTDTTLS---------PGSTTASSLG------PESTTFHSSPGSTETTLLPDNTTASG 4438
Query: 2730 ETSGHSGSFLYQVST--HEQSESSHGWTGPSTRGRQGSRHEQAQDSSRHSASQDGQDTIR 2787
L + ST H + S H P+ GS Q + S+ + + +DT
Sbjct: 4439 ---------LLEASTPVHSSTGSPHTTLSPA-----GSTTRQGE-STTFQSWPNSKDTTP 4483
Query: 2788 GHPGSSRGGRQGYHHEHSVDSSGHSGSHHSHTTSQGRSDASRGQSGSRSASRTTRNEEQS 2847
P ++ + H SS + + +T+ GRS+ S S A+ TT + +S
Sbjct: 4484 APPTTTSAFVELSTTSHGSPSSTPTTHFSASSTTLGRSEESTTVHSSPVATATTPSPARS 4543
Query: 2848 GDGSRHSGSRHHEASTHADISRH---SQAVQGQSEGSRRSRRQGSSVSQDSDSEGHSEDS 2904
S + +S + + H S G+ E S S + + S +
Sbjct: 4544 TTSGLVEESTTYHSSPGSTQTMHFPESNTTSGRGEESTTSHSSTTHTISSAPSTTSALVE 4603
Query: 2905 ERWSGSASRNHHGSAQEQLRDGSRHPRSHQEDRAGHGHSADSSRQSGTRHTQTSSGGQAA 2964
E S +S +A D S +E A H S D++ T+S
Sbjct: 4604 EPTSYHSSPG--STATTHFPDSSTTSGRSEESTASHS-SQDATGTIVLPARSTTSVLLGE 4660
Query: 2965 SSHEQARSSAGERHGSHHQQSADS-SRHSGIGHGQASSAVRDSGHRGYSGSQASDNEGHS 3023
S+ S + E + S S H SS S +S G S
Sbjct: 4661 STTSPISSGSMETTALPGSTTTPGLSEKSTTFHSSPSSTPTTHF------SASSTTLGRS 4714
Query: 3024 EDSDTQSVSAHGQAGSHQQSHQESARGRSGETSGHSGSFLYQVSTHEQSESSHGWTGPST 3083
E+S T S A + + ++ T+ HS Q +S ++ G + S
Sbjct: 4715 EESTTVHSSPVATATTPSPARSTTSGLVEESTAYHSSPGSTQTMHFPESSTASGRSEESR 4774
Query: 3084 RGRQGSRHEQAQDSSRHSASQYGQDTIRGHPGSSRGGRQGYHHEHSVDSSGHSGSHHSHT 3143
+ H + S SA + PGS H +SS
Sbjct: 4775 TSHSSTTHTISSPPSTTSALVEEPTSYHSSPGS-------IATTHFPESS---------- 4817
Query: 3144 TSQGRSDASRGQSGSRSASRTTRNEEQSGDSSRHSVSRHHEASTHADISRHSQAVQGQSE 3203
T+ GRS+ S S + T S R + S S + + +
Sbjct: 4818 TTSGRSEESTASHSSPDTNGITPLPAHFTTSGRIAESTTFYISPGSMETTLASTATTPGL 4877
Query: 3204 GSRRSRRQGSSVSQDSDSEGHSEDSERWSGSASRNHRGSVQEQSRHGSRHPRSHHEDRAG 3263
++ + SS S D S S SG + + Q +S H + P S
Sbjct: 4878 SAKSTILYSSSRSPDQTLSPASMTSSSISGEPTSLYS---QAESTHTTAFPASTTTSGLS 4934
Query: 3264 HGHSADRSRQSGTRHAETSSGGQAASSHEQARSSPGERHGS 3304
+ S+ G+ S G SS Q ++P + GS
Sbjct: 4935 QESTTFHSK-PGSTETTLSPGSITTSSFAQEFTTPHSQPGS 4974
Score = 140 bits (354), Expect = 2e-32
Identities = 458/2156 (21%), Positives = 712/2156 (33%), Gaps = 262/2156 (12%)
Query: 1969 HSADSSRQSGTRHTESSS---RGQAAS------SHEQARSSAGERHGSHHQLQSADSSRH 2019
H DSS SG H+E S+ G A+ SH GE S S +++
Sbjct: 210 HFLDSSTNSG--HSEESTVSHSGPGATGTTLFPSHSATSVFVGEPKTSPITSASMETTAL 267
Query: 2020 SGIGHGQASSAVRDSGHRGYSGSQASD---------SEGHSEDSDTQSVSAQGKAGPHQQ 2070
G ++ + + YS ++ D S G SE S T + + GP
Sbjct: 268 PG---STTTAGLSEKSTTFYSSPRSPDRTLSPARTTSSGVSEKSTT----SHSRPGPTHT 320
Query: 2071 SHKESARGQSGESSGRSGSFLYQVSTHEQSESTHGQSAPSTGGRQGSHYDQAQDSSRHSA 2130
+ G S + S ST + + G + PS+ G + + + + ++ +
Sbjct: 321 IAFPDSTTMPGVSQESTASHSIPGST--DTTLSPGTTTPSSLGPESTTFHSSPGYTKTTR 378
Query: 2131 SQEGQDT--IRGHPGPSRGGRQGSHQEQSVDRSG-HSGSHHSHTTSQGRSDASRGQSGSR 2187
+ T + P H S S H G + + D S SG+
Sbjct: 379 LPDNTTTSGLLEASTPVHSSTGSPHTTLSPSSSTTHEGEPTTFQSWPSSKDTSPAPSGTT 438
Query: 2188 SASRKTYDKEQSGDGSRHSGSHHHEASSWADSSRHSLVGQGQSSGPRTSRPRGSSVSQD- 2246
SA K S S + + H ASS + +G + S P S P ++ +
Sbjct: 439 SAFVKLSTTYHSSPSS--TPTTHFSASS-------TTLGHSEESTPVHSSPVATATTPPP 489
Query: 2247 --SDSEGHSEDSERRSGSASRNHHGSAQEQSRDGSRHPRSHHEDRAGHGHSAESSRQSG- 2303
S + GH E+S +H S GS E GHS ES+ G
Sbjct: 490 ARSATSGHVEESTA--------YHRSP------GSTQTMHFPESSTTSGHSEESATFHGS 535
Query: 2304 -THHAENSSGGQAASSHEQARSSAGERHGSHHQQSADSSRHSGIGHGQASSAVRDSGHRG 2362
TH ++ AA +H SS G +H + S+ S S SS +
Sbjct: 536 TTHTKSSTPSTTAALAHTSYHSSLGSTETTHFRDSSTISGRSEESKASHSSPDAMATTVL 595
Query: 2363 SSGSQASDSEGHSEDSDTQSVSAHGQAGPHQQSHQESTRGRSAGRSGRSGSFLYQVSTHE 2422
+GS S G S S S S A P + G S +S +F S+
Sbjct: 596 PAGSTPSVLVGDSTPSPISSGSMETTALPGSTT--------KPGLSEKSTTF---YSSPR 644
Query: 2423 QSESAH-GRTGTSTGGRQGSHHKQARDSSRHSTSQEGQDTIHG----------------- 2464
++ H + TS+G + S +R S H+T+ G T+ G
Sbjct: 645 SPDTTHLPASMTSSGVSEESTTSHSRPGSTHTTAFPGSTTMPGLSQESTASHSSPGPTDT 704
Query: 2465 --HPGSSSGGRQGSHYEQLVDRSGHSGSH--HSHTTSQGRSDASHGHSGSRSASRQTRND 2520
PGS++ G Y R G + + +TT+ G +AS S + T +
Sbjct: 705 TLSPGSTTASSLGPEYTTFHSRPGSTETTLLPDNTTASGLLEASMPVHSSTRSPHTTLSP 764
Query: 2521 EQSGDGSRHSGSRHHEASSRADSSGHSQVGQGQSEGPRTSRNWGSS-----FSQDSDSQG 2575
S S + H SS+ E TS SS S S + G
Sbjct: 765 AGSTTRQGESTTFHSWPSSKDTRPAPPTTTSAFVEPSTTSHGSPSSIPTTHISARSTTSG 824
Query: 2576 HSEDSERW---SGSASRNHHGSAQEQLRDGSRHPRSHQEDRAGHGHSADSSRQSGTRHTQ 2632
E+S + GS H + G SH H S+ S S
Sbjct: 825 LVEESTTYHSSPGSTQTMHFPESDTTSGRGEESTTSHSS--TTHTISSAPSTTSALVEEP 882
Query: 2633 T---SSGGQAASSHEQARSSAG----ERHGSHHQQSADSS------RHSGIGHGQASSAV 2679
T SS G A++H S+ E SH Q A + + + G+++++
Sbjct: 883 TSYHSSPGSTATTHFPDSSTTSGRSEESTASHSSQDATGTIVLPARSTTSVLLGESTTSP 942
Query: 2680 RDSGHRGYSGSQAS-DNEGHSEDSDTQSVSAHGQAGSHQQS-------HQESARGRSGET 2731
SG + S G SE S T S A + + +ES RS
Sbjct: 943 ISSGSMETTALPGSTTTPGLSERSTTFHSSPRSPATTLSPASTTSSGVSEESTTSRSRPG 1002
Query: 2732 SGHSGSFLYQVST------HEQSESSHGWTGPSTRGRQGSRHEQAQDSSRHSASQDGQDT 2785
S H+ +F +T S SS G T + + +Q+S+ +S DT
Sbjct: 1003 STHTTAFPDSTTTPGLSRHSTTSHSSPGSTDTTLLPASTTTSGPSQESTTSHSSSGSTDT 1062
Query: 2786 IRGHPGSSRGGRQGYHHE--HSVDSSGHSGSHHSHTTSQGRSDASRGQSGSRSASRTTRN 2843
PGS+ G HS S H+ TTS G +AS S + RTT +
Sbjct: 1063 ALS-PGSTTALSFGQESTTFHSNPGSTHTTLFPDSTTSSGIVEASTRVHSSTGSPRTTLS 1121
Query: 2844 EEQS---GDGSRHSGSRHHEASTHADISRHSQAVQGQSEGSRRSRRQGSSVS----QDSD 2896
S G + + H ASTH S S A E + R GS+ + S
Sbjct: 1122 PASSTSPGLQGESTAFQTHPASTHTTPSPPSTATAPVEESTTYHRSPGSTPTTHFPASST 1181
Query: 2897 SEGHSEDSERWSGSASRNHHGSAQEQLRDGSRHPRSHQEDRAGHGHSADSSRQSGTRHTQ 2956
+ GHSE S + S + P S +G G S S G+
Sbjct: 1182 TSGHSEKSTIFHSSPDAS------------GTTPSSAHSTTSGRGESTTSRISPGSTEIT 1229
Query: 2957 TSSGGQAASSHEQARSSAGERHGSHHQQSADSSRHS-GIGHGQASSAVRDSGHRGYSGSQ 3015
T G +A ++ S + +S S G+G +S +
Sbjct: 1230 TLPGSTTTPGLSEASTTFYSSPRSPTTTLSPASMTSLGVGEESTTSRSQPGSTHSTVSPA 1289
Query: 3016 ASDNEGHSEDSDTQSVSAHGQAGSHQQSHQESARGRSGE-TSGHSGSFLYQVSTHEQSES 3074
++ G SE+S T S+ G + H + E T+ HS + + +
Sbjct: 1290 STTTPGLSEESTTVYSSSRGSTETTVFPHSTTTSVHGEEPTTFHSRPASTHTTLFTEDST 1349
Query: 3075 SHGWTGPSTRGRQGSRHEQAQDSSRHSASQYGQDTIRGHPGSSRGGRQGYHHEHSVDSSG 3134
+ G T ST Q + + + G+++ P SS S+G
Sbjct: 1350 TSGLTEESTAFPGSPASTQTGLPATLTTADLGEESTT-FPSSS-------------GSTG 1395
Query: 3135 HSGSHHSHTTS--QGRSDASRGQSGSRSASRTTRNEEQSGDSSRHSVSRHHEASTHADIS 3192
S TTS G S SR S + + S + + S A +S
Sbjct: 1396 TKLSPARSTTSGLVGESTPSRLSPSSTETTTLPGSPTTPSLSEKSTTFYTSPRSPDATLS 1455
Query: 3193 RHSQAVQGQSEGSRRSRRQGSSVSQDSDSEGHSEDSERWSGSASRNHRGSVQEQSRHGSR 3252
+ G SE S S Q S + + + + S + +GS + GS
Sbjct: 1456 PATTTSSGVSEESSTSHSQPGSTHTTAFPDSTTTSDLSQEPTTSHSSQGSTEATLSPGST 1515
Query: 3253 HPRSHHEDRAGHGHS---------ADRSRQSGTRHAETSSGGQAASSH-----EQARSSP 3298
S + S D + SG A T + S H + S+
Sbjct: 1516 TASSLGQQSTTFHSSPGDTETTLLPDDTITSGLVEASTPTHSSTGSLHTTLTPASSTSAG 1575
Query: 3299 GERHGSRHQQSADSSRHSGIPRGQASSAVRDSRHWGSSGSQ--------ASDSEGHSEES 3350
+ + Q SS + P G ++ V S + S S +S + G SEES
Sbjct: 1576 LQEESTTFQSWPSSSDTTPSPPGTTAAPVEVSTTYHSRPSSTPTTHFSASSTTLGRSEES 1635
Query: 3351 DTQSVS-------------------GHGQAGPHQQSHQES----ARDRSGGRSGRSGSFL 3387
T S G P E+ + G S +S +F
Sbjct: 1636 TTVHSSPGATGTALFPTRSATSVLVGEPTTSPISSGSTETTALPGSTTTAGLSEKSTTF- 1694
Query: 3388 YQVSTHEQSESAHGRTRTSTGRRQGSHHEQARDSSRHSASQEGQDTIRGHPGSSRRGRQG 3447
S + + TS+G + S +R S H+ + G T+ PG S+
Sbjct: 1695 -YSSPRSPDTTLSPASTTSSGVSEESTTSHSRPGSTHTTAFPGSTTM---PGVSQESTAS 1750
Query: 3448 SHYEQSVDRSGHSGSHHSHTTSQGRSDASRGQSGSRSASRQTRNDEQSG----------- 3496
S D + GS + + S GS + N SG
Sbjct: 1751 HSSPGSTDTTLSPGSTTASSLGP-ESTTFHSSPGSTETTLLPDNTTASGLLEASTPVHSS 1809
Query: 3497 DGSRH-SWSHHHEASTQADSSRHSQSGQGQSAGPRTSRNQGSSVSQDSDSQGHSEDSERW 3555
GS H + S + Q +S+ + P + V + S G +
Sbjct: 1810 TGSPHTTLSPAGSTTRQGESTTFQSWPSSKDTMPAPPTTTSAFVELSTTSHGSPSSTPTT 1869
Query: 3556 SGSASRNHRGSAQEQSRDGSRHPTSHHEDRAGHGHSAESSRQSGTHHAENSSGGQAASSH 3615
SAS G ++E + S + ++ +S +H SS G + H
Sbjct: 1870 HFSASSTTLGRSEESTTVHSSPVATATTPSPARSTTSGLVEESTAYH---SSPGSTQTMH 1926
Query: 3616 EQARSSAGERHGSHHQQSADSSRHSGIGHGQASSAV--RDSGHRGSSGSQASDSEGHSED 3673
S+A R + S S+ H+ +SA+ + + S GS A+ H D
Sbjct: 1927 FPESSTASGR-SEESRTSHSSTTHTISSPPSTTSALVEEPTSYHSSPGSTATT---HFPD 1982
Query: 3674 SDTQSVSAHGQAGPHQQSHQESTRGRSAGRSGRSGSFLYQVSTHEQSESAHGRAGPSTGG 3733
S T S + H T A RS S ++ S S A P +
Sbjct: 1983 SSTTSGRSEESTASHSSQDATGTIVLPA-RSTTSVLLGESTTSPISSGSMETTALPGSTT 2041
Query: 3734 RQGSRHEQARDSSRHSASQEGQDTIRGHPGSRRGGRQGSYHEQSVDRSGHSGSHHSHTTS 3793
G + ++ HS+ + T+ + G + S S S H+ + TT+
Sbjct: 2042 TPGL---SEKSTTFHSSPRSPATTLSPASTTSSGVSEESTTSHSRPGSTHTTAFPDSTTT 2098
Query: 3794 QG---RSDASHGQSGSRSASRETRNEEQSGDGSRHSGSRHHEASTQADSSRHSQSGQGES 3850
G S SH GS + + SG + S H + D++ S S
Sbjct: 2099 PGLSRHSTTSHSSPGSTDTTLLPASTTTSGPSQESTTS--HSSPGSTDTALSPGSTTALS 2156
Query: 3851 AGSRRSRRQGSSVSQDSDSEAYPEDSERRSESASRNHH--GSSREQ-SRDGSRHPGSSHR 3907
G + S S + S E+++R H GS R S S PG
Sbjct: 2157 FGQESTTFHSSPGSTHTTLFPDSTTSSGIVEASTRVHSSTGSPRTTLSPASSTSPGLQGE 2216
Query: 3908 DTASHVQSSPVQSDSSTAKEHGHFSSLSQDSAYHSGIQSRGSPHSSSSYHYQSEGT 3963
TA Q+ P + ++ + + + + + YH SP S+ + H+ + T
Sbjct: 2217 STA--FQTHPASTHTTPSPPSTATAPVEESTTYHR------SPGSTPTTHFPASST 2264
>gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens]
Length = 2752
Score = 183 bits (465), Expect = 3e-45
Identities = 447/2027 (22%), Positives = 723/2027 (35%), Gaps = 291/2027 (14%)
Query: 147 TGGKRHESSSEKKERKGYSPTHREEEYGKNHHNSSKKEKNKTENTRLGDNRKR------- 199
T G + S + R+G P ++ EE + + K N L RKR
Sbjct: 15 TNGYVQRNLSLVRGRRGERPDYKGEEELRRLEAALVKRPNPDI---LDHERKRRVELRCL 71
Query: 200 -LSERLEEKEDNEEGVYDYENTGRMT--QKWIQSGHIATYYTIQDEAYDTTDSLLEEN-K 255
L E +EE+ E+ + + T R+ +K + G Q A T L E N K
Sbjct: 72 ELEEMMEEQGYEEQQIQEKVATFRLMLLEKDVNPGG-KEETPGQRPAVTETHQLAELNEK 130
Query: 256 IYERSRSSDGKSSSQVNRS-------------------------RHENTSQVPLQESRTR 290
ER R++ G S S V+ S R ++S+ P + + +
Sbjct: 131 KNERLRAAFGISDSYVDGSSFDPQRRAREAKQPAPEPPKPYSLVRESSSSRSPTPKQKKK 190
Query: 291 KRRGSRVSQDRDSEGHSEDSERHSGSASRNHHGSAWEQSRDGSRHPRSHDEDRASHGHSA 350
K++ R R SE S ER S + H +S R RS
Sbjct: 191 KKKKDR---GRRSESSSPRRERKKSSKKKKHRS----ESESKKRKHRSPTPKSKRKSKDK 243
Query: 351 DSSRQSGTRHAETSSRGQTASSHEQARSSPGERHGSGHQQSADSSRHSATGRGQASSAVS 410
R T A S R ++S + A SS R S +SA + H+ G++ S S
Sbjct: 244 KRKRSRSTTPAPKSRRAHRSTSADSASSSDTSRSRS---RSAAAKTHTTALAGRSPSPAS 300
Query: 411 DRGHRGSS-----GSQASDSEGHSENSDTQSVSGHGKAGLRQQSHQESTRGRSGERSG-- 463
R G + G+ ++ E + Q S + ++ + S ERS
Sbjct: 301 GRRGEGDAPFSEPGTTSTQRPSSPETATKQPSSPYEDKDKDKKEKSATRPSPSPERSSTG 360
Query: 464 ------------RSGSSLYQVSTHEQPDSAHGRTGTSTGGRQGSHHEQARDSSRHSASQE 511
R G S ++T ++ R S + + S+S+
Sbjct: 361 PEPPAPTPLLAERHGGSPQPLATTPLSQEPVNPPSEASPTRDRSPPKSPEKLPQSSSSES 420
Query: 512 GQDTIRGHPGSSRGGRQGSHHEQSVNRSGHSGSHHSHTTSQGRSDASHGQSGSRSASRQT 571
+ P ++ R S +S + GSH ++S + SHG++ + T
Sbjct: 421 SPPS----PQPTKVSRHASSSPESPKPAPAPGSHREISSSPTSKNRSHGRAKRDKSHSHT 476
Query: 572 RNEEQSGDGTRHSGSRHHEASSQADSSRHSQVGQGQSSGPRTSRNQGSSVSQDSDSQGHS 631
+ + + R S HS+ Q R+++ G S S + S
Sbjct: 477 PSRRMGRSRSPATAKRGRSRSRTPTKRGHSRSRSPQWRRSRSAQRWGRSRSPQRRGRSRS 536
Query: 632 EDSERWSGSASRNHHGSAQ--EQSRDGSRHP------RSHHEDRAGHGHSADSSRKSGTR 683
WS S + G ++ + R SR P RS R G S +R+
Sbjct: 537 PQRPGWSRSRNTQRRGRSRSARRGRSHSRSPATRGRSRSRTPARRGRSRSRTPARRRSRS 596
Query: 684 HT----QNSSSGQAASSHEQARSSAGERHGSRHQLQSADSSRHSGTGHGQASSAVRDSGH 739
T ++ S A ++R+ A R +R ++ SR G++ S R
Sbjct: 597 RTPTRRRSRSRTPARRGRSRSRTPARRRSRTRSPVRRRSRSRSPARRSGRSRS--RTPAR 654
Query: 740 RGSSGSQATDSEGHSEDSDTQSVSGHGQAGHHQQSHQESARDRSGERSR-RSGSFLYQVS 798
RG S S+ G S SG ++ + + +R R+ R R RS S + +
Sbjct: 655 RGRSRSRTPARRGRSRSRTPARRSGRSRS--RTPARRGRSRSRTPRRGRSRSRSLVRRGR 712
Query: 799 THKQSESSHGWTGPSTGVRQGSHHEQ--ARDNSRHSASQDGQDTIRGHPGSSRRGRQGSH 856
+H ++ G +G S+ + S Q +R NS + + R SS R + S
Sbjct: 713 SHSRTPQRRGRSGSSSERKNKSRTSQRRSRSNSSPEMKKSRISSRRSRSLSSPRSKAKSR 772
Query: 857 HEQSVDRSGHSGSHHSHTTS---QGRSDASRGQSGSRSASRTTRN------EEQSRDGSR 907
SG S + + + RS +S+ ++ SR+ R +R+ +++S+ SR
Sbjct: 773 LSLRRSLSGSSPCPKQKSQTPPRRSRSGSSQPKAKSRTPPRRSRSSSSPPPKQKSKTPSR 832
Query: 908 HSGSRHHEASSHADISRHSQAGQGQ------SEGSRTSRRQGSSVSQDSDSEGHSEDSER 961
S H +S H + + QG +E S T +R+ S D E S R
Sbjct: 833 QS---HSSSSPHPKVKSGTPPRQGSITSPQANEQSVTPQRR-SCFESSPDPELKSRTPSR 888
Query: 962 WSGSAS---------------------------------RNHRGSAQEQ----------S 978
S S S R+H GS+
Sbjct: 889 HSCSGSSPPRVKSSTPPRQSPSRSSSPQPKVKAIISPRQRSHSGSSSPSPSRVTSRTTPR 948
Query: 979 RHGSRHPRSHHEDR--AGHGHSADSSRQS----GTPHAETSSGGQAASSHEQARSSPG-E 1031
R S P S+ E R + HS SS + TP ++ SG + +A++ PG
Sbjct: 949 RSRSVSPCSNVESRLLPRYSHSGSSSPDTKVKPETPPRQSHSGSISPYPKVKAQTPPGPS 1008
Query: 1032 RHGSR----HQQSADSSRHSGIPRRQASSAVRDSGHWGSS---------GSQASDSEGHS 1078
GS+ ++S DS S + V+ S G S Q+ S H
Sbjct: 1009 LSGSKSPCPQEKSKDSLVQSCPGSLSLCAGVKSSTPPGESYFGVSSLQLKGQSQTSPDHR 1068
Query: 1079 EESDTQSVSGHGQDGPHQQSHQESARDWSGGRSGRSGSFIYQVSTHEQSESAHGRTRTST 1138
++ + V + P QS +++ GGRS RS S + ++++ G S
Sbjct: 1069 SDTSSPEVRQSHSESPSLQSKSQTSP--KGGRS-RSSSPVTELASRSPIRQDRGEFSASP 1125
Query: 1139 GRRQGSHHEQARDSSRHSASQEGQDTIRAHPGSRRGGRQGSHHEQSVDRSGHSGSHHSHT 1198
+ G EQ+R S S ++P +VD + G T
Sbjct: 1126 MLKSGMSPEQSRFQSDSS----------SYP--------------TVDSNSLLGQSRLET 1161
Query: 1199 TSQGRSDASHGQSGSRSASRQTRKDKQSGDGSRHSGSRHHEAASWADSSRHSQVGQEQSS 1258
A Q + +AS +KDK S + R + + D+ R + +
Sbjct: 1162 AESKEKMALPPQEDA-TASPPRQKDKFSPFPVQ---DRPESSLVFKDTLRTPPRERSGAG 1217
Query: 1259 GSRTSRHQGSSVSQDSDSERHSDDSERLSGSASR--NHHGSSREQSRDGSRHPGFHQEDR 1316
S ++ Q S++ S E + E+ A + +H S ++ + E+R
Sbjct: 1218 SSPETKEQNSALPTSSQDEELMEVVEKSEEPAGQILSHLSSELKEMSTSNFESSPEVEER 1277
Query: 1317 ASHGHSADSSRQSGTHHTESSSHGQAVSSHEQARSSPGERHGSRHQQSADSS-RHSGIGH 1375
+ + D S +S + +AV A S G H++ ++S R + G
Sbjct: 1278 PAVSLTLDQS--------QSQASLEAVEVPSMASSWGGPHFSPEHKELSNSPLRENSFG- 1328
Query: 1376 RQASSAVRDSGHRGSSGSQVTNSEGHSEDSDTQSVSAHGQAGPHQQSHKESARGQSGESS 1435
+ R+SG G+ + +SE ED + ++ + P ++S R SS
Sbjct: 1329 --SPLEFRNSGPLGTEMNTGFSSE-VKEDLNGPFLN-QLETDPSLDMKEQSTRSSGHSSS 1384
Query: 1436 GRSRSFLYQ--VSSHEQSESTHGQTAPSTGGRQGSRHEQARNSSRHSASQDG---QDTIR 1490
S + + +SS++ S P T R+ S +S+ +DG + R
Sbjct: 1385 ELSPDAVEKAGMSSNQSISSPVLDAVPRTPSRERS------SSASSPEMKDGLPRTPSRR 1438
Query: 1491 GHPGSSRGGRQGSYHEQSVDRSGHS-GYHHSHTTP-QGRSDASHGQSGPRSASRQTRNEE 1548
GSS G R GS SG S G TP +GRS+ S A QT
Sbjct: 1439 SRSGSSPGLRDGSGTPSRHSLSGSSPGMKDIPRTPSRGRSECD--SSPEPKALPQTPRPR 1496
Query: 1549 QSGDGSRHSGSRHHEPSTRAGSSRHSQVGQGESAGSKTSRRQGSSVSQDRDSEGHSEDSE 1608
S ++ P R S S V Q A + +R S SQ+ D + + E
Sbjct: 1497 SRSPSSPELNNKCLTPQ-RERSGSESSVDQKTVARTPLGQRSRSGSSQELDVKPSASPQE 1555
Query: 1609 RRSESASRNHYGSAREQSRHGSRNPRSHQEDRASHGHSAESSRQSGTRHAETSSGGQAAS 1668
R +S + R R SR+ S + D SR S R S G +
Sbjct: 1556 RSESDSSPDSKAKTRTPLRQRSRSGSSPEVD--------SKSRLSPRR----SRSGSSPE 1603
Query: 1669 SQEQARSSPGERHGSRHQQSADSSTDSGTGRRQDSSVVGDSGNRGSSGSQASDSEGHSEE 1728
+++ R++P + GS + RR S S RG S +S +E E
Sbjct: 1604 VKDKPRAAPRAQSGSDSSPEPKAPAPRALPRRSRSG--SSSKGRGPSPEGSSSTESSPEH 1661
Query: 1729 SDTQSVSAHG-QAGPHQQSHQESTRGQSGERSGRSGSFLYQVSTHEQSESAHGRTGPSTG 1787
+ G ++ P ++ + + RS + ++S +S S + P T
Sbjct: 1662 PPKSRTARRGSRSSPEPKTKSRTPPRRRSSRSSPELTRKARLSRRSRSAS----SSPETR 1717
Query: 1788 GRQRSRHEQARDSSRHSASQEGQDTIRGHPGS-------SRGGRQGSHYEQSVDSSGHSG 1840
R RH ++ S +++ + + R S SR GR S + + S S
Sbjct: 1718 SRTPPRHRRSPSVSSPEPAEKSRSSRRRRSASSPRTKTTSRRGRSPSPKPRGLQRS-RSR 1776
Query: 1841 SHHSHTTSQERSD-------VSRGQSGSRSVSRQTRNEKQSGDGSRHSGSRHHEASSRAD 1893
S T + R D SR + SRS SR TR ++ G HS S + SSR
Sbjct: 1777 SRREKTRTTRRRDRSGSSQSTSRRRQRSRSRSRVTR--RRRGGSGYHSRSPARQESSRTS 1834
Query: 1894 SSRHSQVGQGQSSGPRTSRNQGSSVSQDSDSQGHSEDSERWSGSASRNHLGSAWEQSRDG 1953
S R +G+S P TSR + S + + W S SR S R
Sbjct: 1835 SRRR----RGRSRTPPTSRKRSRSRTSPAP----------WKRSRSR---ASPATHRRSR 1877
Query: 1954 SRHPGSHHEDRAGHGHSADSSRQSGTRHTESSSRGQAASSHEQARSS 2000
SR P R+ S S R+S +R + + R ++ +S R S
Sbjct: 1878 SRTPLISRR-RSRSRTSPVSRRRSRSRTSVTRRRSRSRASPVSRRRS 1923
Score = 174 bits (440), Expect = 2e-42
Identities = 588/2781 (21%), Positives = 932/2781 (33%), Gaps = 370/2781 (13%)
Query: 1211 SGSRSASRQTRKDKQSGDGSRHSGSRHHEAASWADSSRHSQVGQEQSSGSRTSRHQGSSV 1270
S SRS + + +K K+ D R S S S +E+ S+ +H+ S
Sbjct: 178 SSSRSPTPKQKKKKKKKDRGRRSES--------------SSPRRERKKSSKKKKHRSES- 222
Query: 1271 SQDSDSERHSDDSERLSGSASRNHHGSSREQSRDGSRHPGFHQEDRASHGHSADSSRQSG 1330
+S +H + + + R R++SR + P + RA SADS+ S
Sbjct: 223 --ESKKRKHRSPTPK----SKRKSKDKKRKRSRSTTPAP---KSRRAHRSTSADSASSSD 273
Query: 1331 THHTESSSHGQAVSSHEQARSSPGERHGSRHQQSADSSRHSGIGHRQASS---AVRDSGH 1387
T + S S + A SP G R + A S ++ SS A +
Sbjct: 274 TSRSRSRSAAAKTHTTALAGRSPSPASGRRGEGDAPFSEPGTTSTQRPSSPETATKQPSS 333
Query: 1388 RGSSGSQVTNSEGHSEDSDTQSVSAHGQAGPHQQSHKESARGQSGESSGRSRSFLYQVSS 1447
+ + + S + S+ G P G S + + V+
Sbjct: 334 PYEDKDKDKKEKSATRPSPSPERSSTGPEPPAPTPLLAERHGGSPQPLATTPLSQEPVNP 393
Query: 1448 HEQSESTHGQTAPSTGGR--QGSRHEQARNS------SRHSASQDGQDTIRGHPGSSRGG 1499
++ T ++ P + + Q S E + S SRH++S PGS R
Sbjct: 394 PSEASPTRDRSPPKSPEKLPQSSSSESSPPSPQPTKVSRHASSSPESPKPAPAPGSHREI 453
Query: 1500 RQGSYHEQSVDRSGHSGYHHSHTTPQGRSDASHGQSGPRSASRQTRNEEQSGDGSRHSGS 1559
+ HSHT + + + R SR ++ SR
Sbjct: 454 SSSPTSKNRSHGRAKRDKSHSHTPSRRMGRSRSPATAKRGRSRSRTPTKRGHSRSRSPQW 513
Query: 1560 RHHEPSTRAGSSRHSQVGQGESAGSKTSRRQGSSVSQDRDSEGHSEDSERRSESASRNHY 1619
R + R G SR Q S++ +R G S S++ G S S RR S SR+
Sbjct: 514 RRSRSAQRWGRSRSPQ----RRGRSRSPQRPGWSRSRNTQRRGRSR-SARRGRSHSRSPA 568
Query: 1620 GSAREQSRHGSRNPRSHQEDRASHGHSAESSRQSGTRHAETSSGGQAASSQEQARSSPGE 1679
R +SR +R RS A + + + +R + G++ S R S
Sbjct: 569 TRGRSRSRTPARRGRSRSRTPARRRSRSRTPTRRRSRSRTPARRGRSRSRTPARRRSRTR 628
Query: 1680 RHGSRHQQSADSSTDSGTGRRQDSSVVGDSGNRGSSGSQASDSEGHSEESDTQSVSAHGQ 1739
R +S + SG R + + RG S S+ G S S +
Sbjct: 629 SPVRRRSRSRSPARRSGRSRSRTPA------RRGRSRSRTPARRGRSRSRTPARRSGRSR 682
Query: 1740 AGPHQQSHQESTRGQSGERSGRSG-----SFLYQVSTHEQSESAHGRTGPSTGGRQRSRH 1794
S + RG+S R+ R G S + + +H ++ GR+G S+ + +SR
Sbjct: 683 ------SRTPARRGRSRSRTPRRGRSRSRSLVRRGRSHSRTPQRRGRSGSSSERKNKSRT 736
Query: 1795 EQARDSSRHSASQEGQ--DTIRGHPGSSRGGRQGSHYE--QSVDSSGHSGSHHSHTTSQE 1850
Q R S S + + R SS + S +S+ S S T +
Sbjct: 737 SQRRSRSNSSPEMKKSRISSRRSRSLSSPRSKAKSRLSLRRSLSGSSPCPKQKSQTPPRR 796
Query: 1851 -RSDVSRGQSGSRSVSRQTRNEKQSGDGSRHSGSRHHEASSRADSSRHSQVGQGQSSGPR 1909
RS S+ ++ SR+ R++R+ + S+ S + SS H +V G
Sbjct: 797 SRSGSSQPKAKSRTPPRRSRSSSSPPPKQK---SKTPSRQSHSSSSPHPKVKSG------ 847
Query: 1910 TSRNQGSSVSQDSDSQGHSEDSERWSGSASRNHLGSAWEQSRDGSRHPGSHHEDRAGHGH 1969
T QGS S ++ Q + S+ L +SR SRH S
Sbjct: 848 TPPRQGSITSPQANEQSVTPQRRSCFESSPDPEL-----KSRTPSRHSCSGSSPP--RVK 900
Query: 1970 SADSSRQSGTRHTESSSRGQAASSHEQARSSAGERHGSHHQLQSADSSRHSGIGHGQASS 2029
S+ RQS +R + + +A S Q RS +G S ++ S + R S ++
Sbjct: 901 SSTPPRQSPSRSSSPQPKVKAIISPRQ-RSHSGSSSPSPSRVTSRTTPRRSRSVSPCSNV 959
Query: 2030 AVRDSGHRGYSGSQASDSEGHSEDSDTQS----------VSAQGKAGPHQQSHK-----E 2074
R +SGS + D++ E QS V AQ GP K E
Sbjct: 960 ESRLLPRYSHSGSSSPDTKVKPETPPRQSHSGSISPYPKVKAQTPPGPSLSGSKSPCPQE 1019
Query: 2075 SARGQSGESSGRSGSFLYQV-STHEQSESTHGQSAPSTGGRQGSHYDQAQDSSRHSASQE 2133
++ +S S S V S+ ES G S+ G+ + D D+S Q
Sbjct: 1020 KSKDSLVQSCPGSLSLCAGVKSSTPPGESYFGVSSLQLKGQSQTSPDHRSDTSSPEVRQS 1079
Query: 2134 GQDTIRGHPGPSRGGRQGSHQEQSVDRSGHSGSHHSHTTSQGRSDA--SRGQSGSRSASR 2191
++ PS + Q+ + G S S T RS RG+ + +
Sbjct: 1080 HSES------PSLQSKS-----QTSPKGGRSRSSSPVTELASRSPIRQDRGEFSASPMLK 1128
Query: 2192 KTYDKEQSGDGSRHSGSHHHEASSWADSSRHSLVGQGQ-------------------SSG 2232
EQS S ++SS+ +SL+GQ + +S
Sbjct: 1129 SGMSPEQSRFQS--------DSSSYPTVDSNSLLGQSRLETAESKEKMALPPQEDATASP 1180
Query: 2233 PRTSRPRGSSVSQDSDSEGHSEDSERRSGSASRNHHGSAQEQSRDGSRHPRSHH------ 2286
PR QD R+ R+ GS+ E S P S
Sbjct: 1181 PRQKDKFSPFPVQDRPESSLVFKDTLRTPPRERSGAGSSPETKEQNSALPTSSQDEELME 1240
Query: 2287 -----EDRAGH--GHSAESSRQSGTHHAENS---------------SGGQAASSHEQARS 2324
E+ AG H + ++ T + E+S S QA+ + S
Sbjct: 1241 VVEKSEEPAGQILSHLSSELKEMSTSNFESSPEVEERPAVSLTLDQSQSQASLEAVEVPS 1300
Query: 2325 SAGERHGSHHQQSADSSRHSGIGHGQASSAV--RDSGHRGSSGSQASDSEGHSEDSDTQS 2382
A G H +S + S + R+SG G+ + SE ED +
Sbjct: 1301 MASSWGGPHFSPEHKELSNSPLRENSFGSPLEFRNSGPLGTEMNTGFSSEV-KEDLNGPF 1359
Query: 2383 VSAHGQAGPHQQSHQESTRGRSAGRSGRSGSFLYQVSTHEQSESAHGRTGTSTGGRQGSH 2442
++ + P ++STR SG S S L + + S++ S+
Sbjct: 1360 LNQL-ETDPSLDMKEQSTRS-----SGHSSSELSPDAVEKAGMSSN--QSISSPVLDAVP 1411
Query: 2443 HKQARDSSRHSTSQEGQDTIHGHP------GSSSGGRQGSHYEQLVDRSGHSGSHHS--H 2494
+R+ S ++S E +D + P GSS G R GS SG S
Sbjct: 1412 RTPSRERSSSASSPEMKDGLPRTPSRRSRSGSSPGLRDGSGTPSRHSLSGSSPGMKDIPR 1471
Query: 2495 TTSQGRSDASHG----------HSGSRSASRQTRNDEQSGDGSRHSGSRHHEASSRADSS 2544
T S+GRS+ SRS S N++ SGS E+S +
Sbjct: 1472 TPSRGRSECDSSPEPKALPQTPRPRSRSPSSPELNNKCLTPQRERSGS---ESSVDQKTV 1528
Query: 2545 GHSQVGQGQSEGPRTSRNWGSSFSQDSDSQGHSEDSERWSGSASRNHHGSAQEQLRDGSR 2604
+ +GQ G SQ+ D + + ER +S + + LR
Sbjct: 1529 ARTPLGQRSRSGS----------SQELDVKPSASPQERSESDSSPDSKAKTRTPLR---- 1574
Query: 2605 HPRSHQEDRAGHGHSADSSRQSGTRHTQTSSGGQAASSHEQARSSAGERHGSHHQQSADS 2664
Q R+G DS + R +++ S S + + A R S S +
Sbjct: 1575 -----QRSRSGSSPEVDSKSRLSPRRSRSGS-----SPEVKDKPRAAPRAQSGSDSSPEP 1624
Query: 2665 SRHSGIGHGQASSAVRDSGHRGYSGSQASDNEGHSEDSDTQSVSAHGQAGSHQ-QSHQES 2723
+ + S + S RG S +S E E + G S + ++ +
Sbjct: 1625 KAPAPRALPRRSRSGSSSKGRGPSPEGSSSTESSPEHPPKSRTARRGSRSSPEPKTKSRT 1684
Query: 2724 ARGRSGETSGHSGSFLYQVSTHEQSESSHGWTGPSTRGRQGSRHEQAQDSSRHSASQDGQ 2783
R S + ++S +S SS P TR R RH ++ S ++ +
Sbjct: 1685 PPRRRSSRSSPELTRKARLSRRSRSASS----SPETRSRTPPRHRRSPSVSSPEPAEKSR 1740
Query: 2784 DTIRGHPGSSRGGRQGYHHEHSVDSSGHSGSHHSHTTSQGRSDASRGQSGSRSASRTTRN 2843
+ R SS + T+ +GRS + + + RS SR+ R
Sbjct: 1741 SSRRRRSASSPRTKT--------------------TSRRGRSPSPKPRGLQRSRSRSRRE 1780
Query: 2844 EEQSGDGSRHSGSRHHEASTHADISRHSQAVQGQSEGSRRSRRQGSSVSQDSDSEGHSED 2903
+ ++ SGS SR Q + +S +RR R
Sbjct: 1781 KTRTTRRRDRSGSSQ-------STSRRRQRSRSRSRVTRRRR------------------ 1815
Query: 2904 SERWSGSASRNHHGSAQEQLRDGSRHPRSHQEDRAGHGHSADSSRQSGTRHTQTSSGGQA 2963
GS + + QE R SR R G + +SR+ T + ++
Sbjct: 1816 ----GGSGYHSRSPARQESSRTSSRR-------RRGRSRTPPTSRKRSRSRTSPAPWKRS 1864
Query: 2964 ASSHEQARSSAGERHGSHHQQSADSSRHSGIGHGQASSAVRDSGHRGYSGSQASDNEGHS 3023
S A + SR S + ++ S R S R S S+AS
Sbjct: 1865 RSRASPATHRRSRSRTPLISRRRSRSRTSPVSRRRSRS--RTSVTRRRSRSRASPVSRRR 1922
Query: 3024 EDSDTQSVSAHGQAGSHQQSHQESARGRSGETSGHSGSFLYQVSTHEQSESSHGWTGPST 3083
S T V+ ++ S + + +R R+ + T +S S T P T
Sbjct: 1923 SRSRTPPVTRR-RSRSRTPTTRRRSRSRTPPVTRRRSRSRTPPVTRRRSRSR---TSPIT 1978
Query: 3084 RGRQGSRHE---QAQDSSRHSASQYGQDTIRGHPGSSRGGRQGYH---HEHSVDSSGHSG 3137
R R SR + + SR S + R P + R R S +
Sbjct: 1979 RRRSRSRTSPVTRRRSRSRTSPVTRRRSRSRTSPVTRRRSRSRTPPAIRRRSRSRTPLLP 2038
Query: 3138 SHHSHTTS------QGRSDASRGQSGSRSASRTT---RNEEQSGDSSRHSVSRHHEASTH 3188
S + S + RS R G RS +R+ R SG SS S S A+ +
Sbjct: 2039 RKRSRSRSPLAIRRRSRSRTPRTARGKRSLTRSPPAIRRRSASGSSSDRSRSATPPATRN 2098
Query: 3189 ADISRHSQAVQGQSEGSRRSRRQGSSVSQDS-DSEGHSED--SERWSGSASRNHRGSVQE 3245
SR S S SR S D S G E S R S + GS+ +
Sbjct: 2099 HSGSRTPPVALNSSRMSCFSRPSMSPTPLDRCRSPGMLEPLGSSRTPMSVLQQAGGSMMD 2158
Query: 3246 QSRHGSRHPRSHHEDRAGHGHSADRSRQS------GTRHAETSSGGQAASSHEQARSSPG 3299
G R P H H+ R + GT S ++ +P
Sbjct: 2159 GP--GPRIP-DHQRTSVPENHAQSRIALALTAISLGTARPPPSMSAAGLAARMSQVPAPV 2215
Query: 3300 ERHGSRHQQSADSSRHSGIPRGQASSAVRDSRHWGSSGSQASDSEGHSEESDTQSVSGHG 3359
R +A+ + S IP A++ + S+ + A + + +S T + +
Sbjct: 2216 PLMSLRTAPAANLA--SRIPAASAAAM-----NLASARTPAIPTAVNLADSRTPAAAAAM 2268
Query: 3360 QAGPHQQSHQESARDRSGGRSGRSGSFLYQVSTHEQSESAHGRTRTSTGRRQGSHHEQAR 3419
+ + SA + + R+ + + + + +A T + T ++ +R
Sbjct: 2269 NLASPRTAVAPSAVNLADPRTPTAPAVNLAGARTPAALAALSLTGSGTPPTAANYPSSSR 2328
Query: 3420 DSSRHSASQEGQDTIRGHPGSSRRGRQGSHYEQSVDRSGHSGSHHSHTTSQGRSDASRGQ 3479
T + ++ G + +H V+ +G + S + +
Sbjct: 2329 -------------TPQAPASANLVGPRSAHATAPVNIAGSRTAAALAPASLTSARMAPAL 2375
Query: 3480 SGSRSASRQTRNDEQSGDGSRHSWSHHHEASTQADSSRHSQSGQGQSAGPRTSRNQGSSV 3539
SG+ S + R S A ++ S SQS P S G +
Sbjct: 2376 SGANLTSPRVPLSAYERVSGRTSPPLLDRARSRTPPSAPSQSRMTSERAPSPSSRMGQAP 2435
Query: 3540 SQDSDSQGHSEDSERWSGSASRNHRGS-AQEQSRDGSRHPTSHH----EDRAGHGHSAES 3594
SQ + + S R AQ GS+ +S AG + S
Sbjct: 2436 SQSLLPPAQDQPRSPVPSAFSDQSRCLIAQTTPVAGSQSLSSGAVATTTSSAGDHNGMLS 2495
Query: 3595 SRQSGTHHAENSSGGQAASSHEQARSSAGERHGSHHQQSADSSRHSGIGHGQASSAVRDS 3654
G H++ G AS+ Q S+ + ++S+ SS S +SS+ S
Sbjct: 2496 VPAPGVPHSD--VGEPPASTGAQQPSALAALQPAKERRSSSSSSSSSSSSSSSSSS---S 2550
Query: 3655 GHRGSSGSQASDSEGHSEDSDTQSVSAHGQAGPHQQSHQESTRGRS-----AGRSGRSGS 3709
SSGS +SDSEG S + V+ P + GR A R RS S
Sbjct: 2551 SSSSSSGSSSSDSEGSSLPVQPE-VALKRVPSPTPAPKEAVREGRPPEPTPAKRKRRSSS 2609
Query: 3710 FLYQVSTHEQSESAHGRAGPSTGGRQGSRHEQARDSSRH-SASQEGQDTI-------RGH 3761
S+ S S+ + S+ S + SS S ++ G + +
Sbjct: 2610 SSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSPSPAKPGPQALPKPASPKKPP 2669
Query: 3762 PGSRRG------------GRQGSYHEQSVDRSGHSGSHHSHTTSQGRSDASHGQSG-SRS 3808
PG RR R SY R S +S + GQ G SRS
Sbjct: 2670 PGERRSRSPRKPIDSLRDSRSLSYSPVERRRPSPQPSPRDQQSSSSERGSRRGQRGDSRS 2729
Query: 3809 ASRETRNEEQSGDGSRHSGSR 3829
S + R E S RH SR
Sbjct: 2730 PSHKRRRETPSPRPMRHRSSR 2750
Score = 169 bits (429), Expect = 4e-41
Identities = 451/2121 (21%), Positives = 714/2121 (33%), Gaps = 250/2121 (11%)
Query: 550 TSQGRSDASHGQSGSRSASRQTRNEEQSGDGTRHSGSRHHEASSQADSSRHSQVGQGQSS 609
+S RS + + R R+E S R S+ + S+++S + +S
Sbjct: 177 SSSSRSPTPKQKKKKKKKDRGRRSESSSPRRERKKSSKKKKHRSESESKKRKH----RSP 232
Query: 610 GPRTSRNQGSSVSQDSDSQGHSEDSERWSGSASRNHHGSAQ-EQSRDGSRHPRSHHEDRA 668
P++ R + S S + S R S S + S+ +SR S ++H A
Sbjct: 233 TPKSKRKSKDKKRKRSRSTTPAPKSRRAHRSTSADSASSSDTSRSRSRSAAAKTHTTALA 292
Query: 669 GHGHSADSSRKSGTRHTQNSSSGQAASSHEQARSSAGERHGSRHQLQSADSSRHSGTGHG 728
G S S R+ G S G ++ + +A ++ S ++ + D S T
Sbjct: 293 GRSPSPASGRR-GEGDAPFSEPGTTSTQRPSSPETATKQPSSPYEDKDKDKKEKSATRPS 351
Query: 729 QASSAVRDSGHRGSSGSQATD-----SEGHSEDSDTQSVSGHGQAGHHQQSHQESARDRS 783
S R S+G + +E H + + Q + S RDRS
Sbjct: 352 P-------SPERSSTGPEPPAPTPLLAERHGGSPQPLATTPLSQEPVNPPSEASPTRDRS 404
Query: 784 GERSRRSGSFLYQVSTHKQSESSHGWTGPSTGVRQGSHHEQARDNSRHSASQDGQDT-IR 842
+S ++ SESS PS + S H + S A G I
Sbjct: 405 PPKSPE------KLPQSSSSESSP----PSPQPTKVSRHASSSPESPKPAPAPGSHREIS 454
Query: 843 GHPGSSRRGRQGSHHEQSVDRSGHSGSHHSHTTSQGRSDASRGQSGSRSASRTTRNEEQS 902
P S R SH D+S HSHT S R SRS + R +S
Sbjct: 455 SSPTSKNR----SHGRAKRDKS------HSHTPS-------RRMGRSRSPATAKRGRSRS 497
Query: 903 RDGSRHSGSRHHEASSHADISRHSQAGQGQSEGSRTSRRQGSSVSQDSDSEGHSEDSERW 962
R ++ HS++ Q SR+++R G S S S W
Sbjct: 498 RTPTKRG---------------HSRSRSPQWRRSRSAQRWGRSRSPQRRGRSRSPQRPGW 542
Query: 963 SGSASRNHRGSAQ--EQSRHGSRHP------RSHHEDRAGHGHSADSSR---QSGTPHAE 1011
S S + RG ++ + R SR P RS R G S +R +S TP
Sbjct: 543 SRSRNTQRRGRSRSARRGRSHSRSPATRGRSRSRTPARRGRSRSRTPARRRSRSRTPTRR 602
Query: 1012 TSSGGQAASSHEQARSSPGERHGSRHQQSADSSRHSGIPRRQASSAVRDSGHWGSSGSQA 1071
S A +P R SR RR S R G S S+
Sbjct: 603 RSRSRTPARRGRSRSRTPARRRSRTRSPVRRRSRSRSPARRSGRSRSRTPARRGRSRSRT 662
Query: 1072 SDSEGHSEESDTQSVSGHGQDGPHQQSHQESARDWSGGRSGRSGSFIYQVSTHEQSESAH 1131
G S SG + + + +R GRS RS S + + +H ++
Sbjct: 663 PARRGRSRSRTPARRSGRSRSRTPARRGRSRSRTPRRGRS-RSRSLVRRGRSHSRTPQRR 721
Query: 1132 GRTRTSTGRRQGSHHEQARDSSRHSASQEGQDTIRAHPGSRRGGRQGSHHEQSVDRSGHS 1191
GR+ +S+ R+ S Q R S S + S R + S+ RS
Sbjct: 722 GRSGSSSERKNKSRTSQRRSRSNSSPEMKKSRISSRRSRSLSSPRSKAKSRLSLRRSLSG 781
Query: 1192 GSHHSHTTSQ-----GRSDASHGQSGSRSASRQTRKD------KQSGDGSR--HSGSRHH 1238
S SQ RS +S ++ SR+ R++R ++S SR HS S H
Sbjct: 782 SSPCPKQKSQTPPRRSRSGSSQPKAKSRTPPRRSRSSSSPPPKQKSKTPSRQSHSSSSPH 841
Query: 1239 EAASWADSSRHSQVGQEQSSGSRTSRHQGSSVSQDSDSERHSDDSERLSGSAS-----RN 1293
R + Q++ + + S D E S R S S S ++
Sbjct: 842 PKVKSGTPPRQGSITSPQANEQSVTPQRRSCFESSPDPELKSRTPSRHSCSGSSPPRVKS 901
Query: 1294 HHGSSREQSRDGSRHPG----FHQEDRASHGHSADSSRQSGTHHTESSSHGQAVSSHEQA 1349
+ SR S P R+ G S+ S + + T S + S+ ++
Sbjct: 902 STPPRQSPSRSSSPQPKVKAIISPRQRSHSGSSSPSPSRVTSRTTPRRSRSVSPCSNVES 961
Query: 1350 RSSPGERHGSRHQ-------QSADSSRHSGIGHRQASSAVRDSGHRGSSGSQVTNSEGHS 1402
R P H ++ HSG + SGS+ + S
Sbjct: 962 RLLPRYSHSGSSSPDTKVKPETPPRQSHSGSISPYPKVKAQTPPGPSLSGSKSPCPQEKS 1021
Query: 1403 EDSDTQS--------VSAHGQAGPHQQSHKESA---RGQSGES----SGRSRSFLYQVSS 1447
+DS QS P + S+ +GQS S S S + Q S
Sbjct: 1022 KDSLVQSCPGSLSLCAGVKSSTPPGESYFGVSSLQLKGQSQTSPDHRSDTSSPEVRQSHS 1081
Query: 1448 HEQSESTHGQTAPSTGGRQGSRHEQARNSSRHSASQDGQDTIRGHPGSSRGGRQGSYHEQ 1507
S + QT+P GGR S +SR QD RG +S + G EQ
Sbjct: 1082 ESPSLQSKSQTSPK-GGRSRSSSPVTELASRSPIRQD-----RGEFSASPMLKSGMSPEQ 1135
Query: 1508 SVDRSGHSGYHHSHTTPQGRSDASHGQSGPRSASRQTRNEEQSGDGSRHSGSRHHEP--- 1564
S +S S Y P S++ GQS +A + + + + S R +
Sbjct: 1136 SRFQSDSSSY------PTVDSNSLLGQSRLETAESKEKMALPPQEDATASPPRQKDKFSP 1189
Query: 1565 ---STRAGSS-------RHSQVGQGESAGSKTSRRQGSSVSQDRDSEGHSEDSERRSESA 1614
R SS R + + S ++ Q S++ E E E+ E A
Sbjct: 1190 FPVQDRPESSLVFKDTLRTPPRERSGAGSSPETKEQNSALPTSSQDEELMEVVEKSEEPA 1249
Query: 1615 SR--NHYGSAREQSRHGSRNPRSHQEDRASHGHSAESSRQSGTRHAETSSGGQAASSQEQ 1672
+ +H S ++ + E+R + + + S ++ + +A
Sbjct: 1250 GQILSHLSSELKEMSTSNFESSPEVEERPAVSLTLDQS--------QSQASLEAVEVPSM 1301
Query: 1673 ARSSPGERHGSRHQQSADS----STDSGTGRRQDSSVVGDSGNRGSSGSQASDSEG---H 1725
A S G H++ ++S ++ ++S +G N G S D G +
Sbjct: 1302 ASSWGGPHFSPEHKELSNSPLRENSFGSPLEFRNSGPLGTEMNTGFSSEVKEDLNGPFLN 1361
Query: 1726 SEESDTQSVSAHGQAGPHQQSHQESTRGQSGERSGRSGSFLYQVSTHEQSESAH-GRTGP 1784
E+D P ++STR SG S S L + + S++ + P
Sbjct: 1362 QLETD-----------PSLDMKEQSTRS-----SGHSSSELSPDAVEKAGMSSNQSISSP 1405
Query: 1785 STGGRQRSRHEQARDSSRHSASQEGQDTIRGHPGSSRGGRQGSHYEQSVDSSGHSGSHHS 1844
R+ +R+ S ++S E +D + P SR R GS D SG H
Sbjct: 1406 VLDAVPRT---PSRERSSSASSPEMKDGLPRTP--SRRSRSGSS-PGLRDGSGTPSRHSL 1459
Query: 1845 HTTSQERSDVSRGQSGSRSVSRQTRNEKQSGDGSRHSGSRHHEASSRADSSRHSQVGQGQ 1904
+S D+ R S RS + K R + S + + Q +
Sbjct: 1460 SGSSPGMKDIPRTPSRGRSECDSSPEPKALPQTPR----PRSRSPSSPELNNKCLTPQRE 1515
Query: 1905 SSGPRTSRNQ----GSSVSQDSDSQGHSEDSERWSGSASRNHLGSAWEQSRDGSRHPGSH 1960
SG +S +Q + + Q S S E + S S + S+ +R P
Sbjct: 1516 RSGSESSVDQKTVARTPLGQRSRSGSSQELDVKPSASPQERSESDSSPDSKAKTRTP-LR 1574
Query: 1961 HEDRAGHGHSADSSRQSGTRHTESSSRGQAASSHEQARSSAGERHGSHHQLQSADSSRHS 2020
R+G DS + R + S G + ++ R++ + GS + + +
Sbjct: 1575 QRSRSGSSPEVDSKSRLSPRRSRS---GSSPEVKDKPRAAPRAQSGSDSSPEPKAPAPRA 1631
Query: 2021 GIGHGQASSAVRDSGHRGYSGSQASDSEGHSEDSDTQSVSAQGKAGPHQQSHKESARGQS 2080
++ S+ + G S S H S T ++ P +S R S
Sbjct: 1632 LPRRSRSGSSSKGRGPSPEGSSSTESSPEHPPKSRTARRGSRSSPEPKTKSRTPPRRRSS 1691
Query: 2081 GES---------SGRSGSFLYQVSTHEQSESTHGQSAPSTGGRQGSHYDQAQDSSRHSAS 2131
S S RS S T ++ H +S PS + + ++ R ++S
Sbjct: 1692 RSSPELTRKARLSRRSRSASSSPETRSRTPPRHRRS-PSVSSPEPAEKSRSSRRRRSASS 1750
Query: 2132 QEGQDTIRGHPGPSRGGRQGSHQEQSVDRSGHSGSHHSHTTSQGRSDASRGQSGS----R 2187
+ T SR GR S + + + RS T++ R + QS S R
Sbjct: 1751 PRTKTT-------SRRGRSPSPKPRGLQRSRSRSRREKTRTTRRRDRSGSSQSTSRRRQR 1803
Query: 2188 SASRKTYDKEQSGDGSRHSGSHHHEASSWADSSRHSLVGQGQSSGPRTSRPRGSSVSQDS 2247
S SR + + G HS S + SS S R +G+S P TSR R S + +
Sbjct: 1804 SRSRSRVTRRRRGGSGYHSRSPARQESSRTSSRRR----RGRSRTPPTSRKRSRSRTSPA 1859
Query: 2248 DSEGHSEDSERRSGSASRNHHGSAQEQSRDGSRHPRSHHEDRAGHGHSAESSRQSGTHHA 2307
R S + R SR SR S R ++ + R+S + +
Sbjct: 1860 P---WKRSRSRASPATHRRSRSRTPLISRRRSRSRTSPVSRRRSRSRTSVTRRRSRSRAS 1916
Query: 2308 ENSSGGQAASSHEQARSSAGERHGSHHQQSADSSRHSGIGHGQASSAVRDSGHRGSSGSQ 2367
S + + R + R + ++S SR + ++ S R S S+
Sbjct: 1917 PVSRRRSRSRTPPVTRRRSRSRTPTTRRRS--RSRTPPVTRRRSRSRTPPVTRR-RSRSR 1973
Query: 2368 ASDSEGHSEDSDTQSVSAHGQAGPHQQSHQESTRGRSAGRSGRSGSFLYQVSTHEQSESA 2427
S S T V+ + +R R++ + R + +S
Sbjct: 1974 TSPITRRRSRSRTSPVTRRRSRSRTSPVTRRRSRSRTSPVTRRRSRSRTPPAIRRRS--- 2030
Query: 2428 HGRTGTSTGGRQGSHHKQARDSSRHSTSQEGQDTIHGHPGSSSGGRQGSHYEQLVDRSGH 2487
R+ T R+ S + R S S+ P ++ G R + + R
Sbjct: 2031 --RSRTPLLPRKRSRSRSPLAIRRRSRSRT--------PRTARGKRSLTRSPPAIRRRSA 2080
Query: 2488 SGSHHSHTTSQGRSDASHGHSGSRSASRQTRNDEQSG-----------DGSRHSGSRHHE 2536
SGS + S A+ HSGSR+ + S D R G
Sbjct: 2081 SGSSSDRSRS-ATPPATRNHSGSRTPPVALNSSRMSCFSRPSMSPTPLDRCRSPGMLEPL 2139
Query: 2537 ASSRADSSGHSQVGQGQSEGP 2557
SSR S Q G +GP
Sbjct: 2140 GSSRTPMSVLQQAGGSMMDGP 2160
Score = 159 bits (402), Expect = 5e-38
Identities = 441/2027 (21%), Positives = 687/2027 (33%), Gaps = 262/2027 (12%)
Query: 2055 DTQSVSAQGKAGPHQQSHKESARGQSGESSGRSGSFLYQVSTHEQSESTHGQSAPSTGGR 2114
D S Q +A +Q E + S S ++ + G+ + S+ R
Sbjct: 147 DGSSFDPQRRAREAKQPAPEPPKPYSLVRESSSSRSPTPKQKKKKKKKDRGRRSESSSPR 206
Query: 2115 QGSHYDQAQDSSRHSASQEGQDTIRGHPGPSRGGRQGSHQEQ-----SVDRSGHSGSHHS 2169
+ ++ + S + E + R H P+ ++ S ++ S + S H
Sbjct: 207 R----ERKKSSKKKKHRSESESKKRKHRSPTPKSKRKSKDKKRKRSRSTTPAPKSRRAHR 262
Query: 2170 HTTSQGRSDASRGQSGSRSASRKTYDKEQSGDGSRHSGSHHHEASSWADSSRHSLVGQGQ 2229
T++ S + +S SRSA+ KT+ +G + E A S +
Sbjct: 263 STSADSASSSDTSRSRSRSAAAKTHTTALAGRSPSPASGRRGEGD--APFSEPGTTSTQR 320
Query: 2230 SSGPRTSRPRGSSVSQDSDSEGHSEDSERRSGSASRN----------------HHGSAQ- 2272
S P T+ + SS +D D + + + R S S R+ H GS Q
Sbjct: 321 PSSPETATKQPSSPYEDKDKDKKEKSATRPSPSPERSSTGPEPPAPTPLLAERHGGSPQP 380
Query: 2273 ---------------EQSRDGSRHPRSHHEDRAGHGHSAESSRQSG-----THHAENS-- 2310
E S R P E + S+ESS S + HA +S
Sbjct: 381 LATTPLSQEPVNPPSEASPTRDRSPPKSPE-KLPQSSSSESSPPSPQPTKVSRHASSSPE 439
Query: 2311 --SGGQAASSHEQARSSAGERHGSHHQQSADSSRHSGIGHGQASSAVRDSGHRGSSGSQA 2368
A SH + SS ++ SH + D S S + RG S S+
Sbjct: 440 SPKPAPAPGSHREISSSPTSKNRSHGRAKRDKSHSHTPSRRMGRSRSPATAKRGRSRSRT 499
Query: 2369 SDSEGHSEDSDTQ-----SVSAHGQA-GPHQQSHQES------TRGRSAGRSGRSGSFLY 2416
GHS Q S G++ P ++ S +R R+ R GRS S
Sbjct: 500 PTKRGHSRSRSPQWRRSRSAQRWGRSRSPQRRGRSRSPQRPGWSRSRNTQRRGRSRS-AR 558
Query: 2417 QVSTHEQSESAHGRTGTSTGGRQGSHHKQ--ARDSSRHST-----SQEGQDTIHGHPGSS 2469
+ +H +S + GR+ + T R+G + AR SR T S+ G S
Sbjct: 559 RGRSHSRSPATRGRSRSRTPARRGRSRSRTPARRRSRSRTPTRRRSRSRTPARRGRSRSR 618
Query: 2470 SGGRQGSHYEQLVDRSGHSGSHHSHT-TSQGRSDASHGHSGSRSASRQTRNDEQSGDGSR 2528
+ R+ S V R S S + S+ R+ A G S SR+ +R+ R+ +S +R
Sbjct: 619 TPARRRSRTRSPVRRRSRSRSPARRSGRSRSRTPARRGRSRSRTPARRGRS--RSRTPAR 676
Query: 2529 HSGSRHHEASSRADSSGHSQVGQGQSEGPRTSRNWGSSFSQDSDSQGHSEDSERWSGSAS 2588
SG R+ S ++ G+ +S PR R+ S + S + SGS+S
Sbjct: 677 RSG--------RSRSRTPARRGRSRSRTPRRGRSRSRSLVRRGRSHSRTPQRRGRSGSSS 728
Query: 2589 RNHHGSAQEQLRDGSRHPRSHQEDRAGHGHSADSSRQSGTRHTQTSSGGQAASSHEQARS 2648
+ S Q R R+ SR S R SS A S R
Sbjct: 729 ERKNKSRTSQRRS-----------RSNSSPEMKKSRISSRRSRSLSSPRSKAKSRLSLRR 777
Query: 2649 SAGERHGSHHQQSADSSRHSGIGHGQASSAVRDSGHRGYSGSQASDNEGHSEDSDTQSVS 2708
S Q+S R S G Q + R R S++S + + S T S
Sbjct: 778 SLSGSSPCPKQKSQTPPRRSRSGSSQPKAKSRTPPRR----SRSSSSPPPKQKSKTPSRQ 833
Query: 2709 AHGQAGSHQQSHQESARGRSGETSGHSGSFLYQVSTHEQSESSHGWTGPSTRGRQGSRHE 2768
+H + H + + + TS + Q T ++ P + R SRH
Sbjct: 834 SHSSSSPHPKVKSGTPPRQGSITSPQANE---QSVTPQRRSCFESSPDPELKSRTPSRHS 890
Query: 2769 QAQDSSRHSASQDGQDTIRGHPGSSRGGRQGYHHEHSVDSSGHSGSHHSHTTSQGRSDAS 2828
+ S S S + + SG S S TS+ S
Sbjct: 891 CSGSSPPRVKSSTPPRQSPSRSSSPQPKVKAIISPRQRSHSGSSSPSPSRVTSRTTPRRS 950
Query: 2829 RG--------------QSGSRSASRTTRNEEQSGDGSRHSGSRHH----EASTHADISRH 2870
R S S S+S T+ + ++ HSGS +A T S
Sbjct: 951 RSVSPCSNVESRLLPRYSHSGSSSPDTKVKPETPPRQSHSGSISPYPKVKAQTPPGPSLS 1010
Query: 2871 SQAVQGQSEGSRRSRRQG--SSVSQDSDSEGHSEDSERWSGSASRNHHGSAQEQLRDGSR 2928
E S+ S Q S+S + + + E + G +S G Q Q R
Sbjct: 1011 GSKSPCPQEKSKDSLVQSCPGSLSLCAGVKSSTPPGESYFGVSSLQLKG--QSQTSPDHR 1068
Query: 2929 HPRSHQEDRAGHGHSADSSRQSGTR----HTQTSSGGQAASSHEQARSSAGERHGSHHQQ 2984
S E R H S +S T +++SS +S R GE S +
Sbjct: 1069 SDTSSPEVRQSHSESPSLQSKSQTSPKGGRSRSSSPVTELASRSPIRQDRGEFSASPMLK 1128
Query: 2985 SADSSRHSGIGHGQASSAVRDSGHRGYSGSQASDNEGHSEDSDTQSVSAHGQAGSHQQSH 3044
S S S +S DS + + E ++++ A
Sbjct: 1129 SGMSPEQSRFQSDSSSYPTVDSN--------SLLGQSRLETAESKEKMA--------LPP 1172
Query: 3045 QESARGRSGETSGHSGSFLYQVSTHEQSESSHGW-----TGPSTRGRQGSRHEQAQDSSR 3099
QE A F Q ++ ESS + T P R GS E + +S
Sbjct: 1173 QEDATASPPRQKDKFSPFPVQ----DRPESSLVFKDTLRTPPRERSGAGSSPETKEQNSA 1228
Query: 3100 HSASQYGQDTIRGHPGSSRGGRQGYHHEHSVDSSGHSGSHHSHTTSQGRSDASRGQSGSR 3159
S ++ + S Q H S + + S + R S S+
Sbjct: 1229 LPTSSQDEELMEVVEKSEEPAGQILSHLSSELKEMSTSNFESSPEVEERPAVSLTLDQSQ 1288
Query: 3160 SASRTTRNEEQSGDSSRHSVSRHHEASTHADISRHSQAVQGQSEGSRRSRRQGSSVSQDS 3219
S + E S SS H + H ++S + ++ S GS R + +
Sbjct: 1289 SQASLEAVEVPSMASSWGGP---HFSPEHKELS--NSPLRENSFGSPLEFRNSGPLGTEM 1343
Query: 3220 DSEGHSEDSERWSG----SASRNHRGSVQEQSRHGSRHPRSHHE----DRAGHG------ 3265
++ SE E +G + ++EQS S H S ++AG
Sbjct: 1344 NTGFSSEVKEDLNGPFLNQLETDPSLDMKEQSTRSSGHSSSELSPDAVEKAGMSSNQSIS 1403
Query: 3266 --------HSADRSRQSGTRHAETSSG-GQAASSHEQARSSPGERHGS----RHQQSADS 3312
+ R R S E G + S ++ SSPG R GS RH S S
Sbjct: 1404 SPVLDAVPRTPSRERSSSASSPEMKDGLPRTPSRRSRSGSSPGLRDGSGTPSRHSLSGSS 1463
Query: 3313 SRHSGIPRGQASSAVR-----DSRHWGSSGSQASDSEGHSEESDTQSVSGHGQAGPHQQS 3367
IPR + + + + S S E ++ ++G
Sbjct: 1464 PGMKDIPRTPSRGRSECDSSPEPKALPQTPRPRSRSPSSPELNNKCLTPQRERSGSESSV 1523
Query: 3368 HQESARDRSGGRSGRSGSFLY-----QVSTHEQSES-----AHGRTRTSTGRRQGSHHEQ 3417
Q++ G+ RSGS S E+SES + +TRT +R S
Sbjct: 1524 DQKTVARTPLGQRSRSGSSQELDVKPSASPQERSESDSSPDSKAKTRTPLRQRSRSGSSP 1583
Query: 3418 ARDS--------SRHSASQEGQDTIRGHP----GSSRRGRQGSHYEQSVDRSGHSGSHHS 3465
DS SR +S E +D R P GS + +++ R SGS
Sbjct: 1584 EVDSKSRLSPRRSRSGSSPEVKDKPRAAPRAQSGSDSSPEPKAPAPRALPRRSRSGS--- 1640
Query: 3466 HTTSQGRSDASRGQSGSRSASRQTRNDEQSGDGSRHSWSHHHEAST--QADSSRHSQSGQ 3523
+S+GR + G S + S+ + GSR S ++ T + SSR S
Sbjct: 1641 --SSKGRGPSPEGSSSTESSPEHPPKSRTARRGSRSSPEPKTKSRTPPRRRSSRSSPELT 1698
Query: 3524 GQSAGPRTSRNQGSSVS---------QDSDSQGHSEDSERWSGSASRNHRGSAQEQSRDG 3574
++ R SR+ SS + S S E +E+ +SR R ++ +++
Sbjct: 1699 RKARLSRRSRSASSSPETRSRTPPRHRRSPSVSSPEPAEK--SRSSRRRRSASSPRTKTT 1756
Query: 3575 SRHPTSHHEDRAGHGHSAESSRQSGTHHAENSSGGQAASSHEQARSSAGERHGSHHQQSA 3634
SR S G S SR+ T ++ S + R + R ++
Sbjct: 1757 SRRGRSPSPKPRGLQRSRSRSRREKTRTTRRRDRSGSSQSTSRRRQRSRSRSRVTRRRRG 1816
Query: 3635 DSSRHSGIGHGQASSAVRDSGHRGSSGSQ-ASDSEGHSEDSDTQSVSAHGQAGP--HQQS 3691
S HS Q SS RG S + S S S + +A P H++S
Sbjct: 1817 GSGYHSRSPARQESSRTSSRRRRGRSRTPPTSRKRSRSRTSPAPWKRSRSRASPATHRRS 1876
Query: 3692 HQES---TRGRSAGRSGRSGSFLYQVSTHEQSESAHGRAGPSTGGRQGSRHEQA--RDSS 3746
+ +R RS R+ + T + RA P + R SR R S
Sbjct: 1877 RSRTPLISRRRSRSRTSPVSRRRSRSRTSVTRRRSRSRASPVSRRRSRSRTPPVTRRRSR 1936
Query: 3747 RHSASQEGQDTIRGHPGSRRGGRQGSYHEQSVDRSGHSGSHHSHTTSQGR-SDASHGQSG 3805
+ + + R P +RR R + + RS S + S+ R S + +S
Sbjct: 1937 SRTPTTRRRSRSRTPPVTRRRSRSRT-PPVTRRRSRSRTSPITRRRSRSRTSPVTRRRSR 1995
Query: 3806 SRSA--SRETRNEEQSGDGSRHSGSRHHEASTQADSSR-------------------HSQ 3844
SR++ +R S R S SR A + SR S+
Sbjct: 1996 SRTSPVTRRRSRSRTSPVTRRRSRSRTPPAIRRRSRSRTPLLPRKRSRSRSPLAIRRRSR 2055
Query: 3845 SGQGESAGSRRS-RRQGSSVSQDSDSEAYPEDSERRSESASRNHHGS 3890
S +A +RS R ++ + S S + + S + A+RNH GS
Sbjct: 2056 SRTPRTARGKRSLTRSPPAIRRRSASGSSSDRSRSATPPATRNHSGS 2102
Score = 159 bits (401), Expect = 7e-38
Identities = 442/2080 (21%), Positives = 687/2080 (33%), Gaps = 319/2080 (15%)
Query: 86 YESTRKENLPISGHKHRKHSHHDKHEDNKQEENKENRKRPSSLERRNNRKGNKGRSKSPR 145
Y R+ + S +K K + E + R+R S +++ +R ++ + + R
Sbjct: 171 YSLVRESSSSRSPTPKQKKKKKKKDRGRRSESSSPRRERKKSSKKKKHRSESESKKRKHR 230
Query: 146 ETGGKRHESSSEKKERKGYSPTHREEEYGKNHHNSSKKEKNKTENTRLGDNRKRLSERLE 205
K S +KK ++ S T + + H S+ + + +T +R ++
Sbjct: 231 SPTPKSKRKSKDKKRKRSRSTTPAPKS--RRAHRSTSADSASSSDTSRSRSRSAAAKTHT 288
Query: 206 EKEDNEEGVYDYENTGRMTQKWIQSGHIATYYTIQDEAYDTTDSLLEENKIYERSRSSDG 265
G + + G +T E S E+K ++ S
Sbjct: 289 TALAGRSPSPASGRRGEGDAPFSEPGTTSTQRPSSPETATKQPSSPYEDKDKDKKEKSAT 348
Query: 266 KSSSQVNRS---------------RHENTSQV-------------PLQESRTRKRRGSRV 297
+ S RS RH + Q P + S TR R +
Sbjct: 349 RPSPSPERSSTGPEPPAPTPLLAERHGGSPQPLATTPLSQEPVNPPSEASPTRDRSPPKS 408
Query: 298 SQDRDSEGHSEDS---------ERHSGSASRNHH-----GSAWEQSRDGSRHPRSHDEDR 343
+ SE S RH+ S+ + GS E S + RSH +
Sbjct: 409 PEKLPQSSSSESSPPSPQPTKVSRHASSSPESPKPAPAPGSHREISSSPTSKNRSHGRAK 468
Query: 344 ASHGHSADSSRQSG-TRHAETSSRGQTASSHEQARSSPGERHGSGHQQSADSSRHSATGR 402
HS SR+ G +R T+ RG++ RS + G +S R + R
Sbjct: 469 RDKSHSHTPSRRMGRSRSPATAKRGRS-------RSRTPTKRGHSRSRSPQWRRSRSAQR 521
Query: 403 GQASSAVSDRGHRGSSGSQASDSEGHSENSDTQSVSGHGKAGLRQQSHQES--TRGRSGE 460
S + RG S++ G S + +TQ G ++ R +SH S TRGRS
Sbjct: 522 WGRSRSPQRRGR-----SRSPQRPGWSRSRNTQR-RGRSRSARRGRSHSRSPATRGRSRS 575
Query: 461 RS----GRSGS-------SLYQVSTHEQPDSA----HGRTGTSTGGRQGSHHE---QARD 502
R+ GRS S S + T + S GR+ + T R+ S + R
Sbjct: 576 RTPARRGRSRSRTPARRRSRSRTPTRRRSRSRTPARRGRSRSRTPARRRSRTRSPVRRRS 635
Query: 503 SSRHSASQEGQDTIR-----GHPGSSRGGRQG-SHHEQSVNRSGHSGSHHSHTTSQGRSD 556
SR A + G+ R G S R+G S RSG S S + RS
Sbjct: 636 RSRSPARRSGRSRSRTPARRGRSRSRTPARRGRSRSRTPARRSGRSRSRTPARRGRSRSR 695
Query: 557 ASH-GQSGSRSASRQTRNEEQSGDGTRHSGSRHHEASSQADSSRHSQVGQGQSSGPRTSR 615
G+S SRS R+ R+ ++ SGS +S + + SR SQ +S P +
Sbjct: 696 TPRRGRSRSRSLVRRGRSHSRTPQRRGRSGS----SSERKNKSRTSQRRSRSNSSPEMKK 751
Query: 616 NQGSSVSQDSDSQGHSEDSERWSGSASRNHHGSAQEQ--------SRDGSRHPRSHHEDR 667
++ SS S S S+ R S S + +Q SR GS P++
Sbjct: 752 SRISSRRSRSLSSPRSKAKSRLSLRRSLSGSSPCPKQKSQTPPRRSRSGSSQPKAKSRTP 811
Query: 668 AGHGHSADSSRKSGTRHTQNSSSGQAASSHEQARSSAGERHGS----------------- 710
S+ S T + S ++S H + +S R GS
Sbjct: 812 PRRSRSSSSPPPKQKSKTPSRQSHSSSSPHPKVKSGTPPRQGSITSPQANEQSVTPQRRS 871
Query: 711 ------RHQLQSADSSRHSGTGHGQASSAVRDSGHRGSSGSQATDSEGHSEDSDTQSVSG 764
+L+S SRHS +G SS R + S+ + + S S +++
Sbjct: 872 CFESSPDPELKSRTPSRHSCSG----SSPPRV---KSSTPPRQSPSRSSSPQPKVKAIIS 924
Query: 765 HGQAGHHQQSHQESAR--DRSGERSRRSGSFLYQVSTHKQSESSH-GWTGPSTGVRQGSH 821
Q H S +R R+ R RS S V + SH G + P T V+ +
Sbjct: 925 PRQRSHSGSSSPSPSRVTSRTTPRRSRSVSPCSNVESRLLPRYSHSGSSSPDTKVKPETP 984
Query: 822 HEQARDNSRHSASQDGQDTIRGH--PGSSRRGRQGSHHEQS------------------V 861
Q+ HS S ++ PG S G + ++ V
Sbjct: 985 PRQS-----HSGSISPYPKVKAQTPPGPSLSGSKSPCPQEKSKDSLVQSCPGSLSLCAGV 1039
Query: 862 DRSGHSGSHH-----------SHTTSQGRSDASRG---QSGSRSASRTTRNEEQSRDGSR 907
S G + S T+ RSD S QS S S S ++++ + G
Sbjct: 1040 KSSTPPGESYFGVSSLQLKGQSQTSPDHRSDTSSPEVRQSHSESPSLQSKSQTSPKGGRS 1099
Query: 908 HSGSRHHEASSHADI-------SRHSQAGQGQS-EGSRTSRRQGSSVSQDSDSE-GHS-- 956
S S E +S + I S G S E SR S + DS+S G S
Sbjct: 1100 RSSSPVTELASRSPIRQDRGEFSASPMLKSGMSPEQSRFQSDSSSYPTVDSNSLLGQSRL 1159
Query: 957 ---EDSERWSGSASRNHRGSAQEQSRHGSRHP---------------RSHHEDRAGHGHS 998
E E+ + + S Q S P R+ +R+G G S
Sbjct: 1160 ETAESKEKMALPPQEDATASPPRQKDKFSPFPVQDRPESSLVFKDTLRTPPRERSGAGSS 1219
Query: 999 ADSSRQSGTPHAETSSGGQAASSHEQARSSPGER---HGSRHQQSADSSRHSGIPRRQAS 1055
++ Q+ TSS + + P + H S + +S P +
Sbjct: 1220 PETKEQNSA--LPTSSQDEELMEVVEKSEEPAGQILSHLSSELKEMSTSNFESSPEVEER 1277
Query: 1056 SAVRDSGHWGSSGSQASDSEGHSEESDTQSVSGHGQDGPHQQSHQESARDWSGG------ 1109
AV S S SQAS E S S G H++ R+ S G
Sbjct: 1278 PAV--SLTLDQSQSQAS-LEAVEVPSMASSWGGPHFSPEHKELSNSPLRENSFGSPLEFR 1334
Query: 1110 -----------------RSGRSGSFIYQVSTHEQSESAHGRTRTS---TGRRQGSHHEQA 1149
+ +G F+ Q+ T + TR+S + E+A
Sbjct: 1335 NSGPLGTEMNTGFSSEVKEDLNGPFLNQLETDPSLDMKEQSTRSSGHSSSELSPDAVEKA 1394
Query: 1150 RDSSRHSASQEGQDTIRAHPGSRRGGRQGSHHEQSV--------DRSGHSGSHHSHTTSQ 1201
SS S S D + P R S + RSG S + +
Sbjct: 1395 GMSSNQSISSPVLDAVPRTPSRERSSSASSPEMKDGLPRTPSRRSRSGSSPGLRDGSGTP 1454
Query: 1202 GRSDASHGQSGSRSASRQTRKDKQSGDGSRHSGSR------HHEAASWADSSRHSQVGQE 1255
R S G + R + + D S + + S + + Q
Sbjct: 1455 SRHSLSGSSPGMKDIPRTPSRGRSECDSSPEPKALPQTPRPRSRSPSSPELNNKCLTPQR 1514
Query: 1256 QSSGSRTSRHQGSSVSQDSDSERHSDDSERL----SGSASRNHHGSSREQSRDGSRHPGF 1311
+ SGS +S Q + S S+ L S S S S+ +R P
Sbjct: 1515 ERSGSESSVDQKTVARTPLGQRSRSGSSQELDVKPSASPQERSESDSSPDSKAKTRTP-L 1573
Query: 1312 HQEDRASHGHSADSSRQSGTHHTESSSHGQAVSSHEQARSSPGERHGSRHQQSADSSRHS 1371
Q R+ DS + + S S + ++ R++P + GS +
Sbjct: 1574 RQRSRSGSSPEVDSKSRLSPRRSRSGSSPEV---KDKPRAAPRAQSGSDSSPEPKAPAPR 1630
Query: 1372 GIGHRQAS-SAVRDSGHRGSSGSQVTNSEGHSEDSDTQSVSAHGQAGPHQQSHKESARGQ 1430
+ R S S+ + G S +S H S T + P +S R
Sbjct: 1631 ALPRRSRSGSSSKGRGPSPEGSSSTESSPEHPPKSRTARRGSRSSPEPKTKSRTPPRRRS 1690
Query: 1431 SGESSGRSRSFLYQVSSHEQSESTHGQTAPSTGGRQGSRHEQARNSSRHSASQDGQDTIR 1490
S S +R S S S P T R RH ++ + S ++ + + R
Sbjct: 1691 SRSSPELTRKARLSRRSRSASSS------PETRSRTPPRHRRSPSVSSPEPAEKSRSSRR 1744
Query: 1491 GHPGSSRGGRQGSYHEQSVDRSGHSGYHHSHTTPQGRSDASHGQSGPRSASRQTRNEEQS 1550
SS + T+ +GRS + + RS SR R + ++
Sbjct: 1745 RRSASSPRTKT--------------------TSRRGRSPSPKPRGLQRSRSRSRREKTRT 1784
Query: 1551 GDGSRHSGSRHHEPSTRAGSSRHSQVGQGESAG----SKTSRRQGSSVSQDRDSEGHSED 1606
SGS R S S+V + G S++ RQ SS + R G S
Sbjct: 1785 TRRRDRSGSSQSTSRRRQRSRSRSRVTRRRRGGSGYHSRSPARQESSRTSSRRRRGRSR- 1843
Query: 1607 SERRSESASRNHYGSAREQSRHGSRNPRSHQEDRASH---GHSAESSRQSGTRHAETSSG 1663
+ S SR+ A + +P +H+ R+ SR S + S
Sbjct: 1844 TPPTSRKRSRSRTSPAPWKRSRSRASPATHRRSRSRTPLISRRRSRSRTSPVSRRRSRSR 1903
Query: 1664 GQAASSQEQARSSPGERHGSRHQ-----QSADSSTDSGTGRRQDSSVVGDSGNRGSSGS- 1717
+ ++R+SP R SR + + S T RR S + R S +
Sbjct: 1904 TSVTRRRSRSRASPVSRRRSRSRTPPVTRRRSRSRTPTTRRRSRSRTPPVTRRRSRSRTP 1963
Query: 1718 QASDSEGHSEESDTQSVSAHGQAGPHQQSHQESTRGQSGERSGRSGSFLYQVSTHEQSES 1777
+ S S + + P + S R RS + T +S S
Sbjct: 1964 PVTRRRSRSRTSPITRRRSRSRTSPVTRRRSRSRTSPVTRRRSRSRT---SPVTRRRSRS 2020
Query: 1778 AHGRTGPSTGGRQRSRH---EQARDSSRHSASQEGQDTIRGHPGSSRGGRQGSHYEQSVD 1834
RT P+ R RSR + R SR + + R P ++RG R + ++
Sbjct: 2021 ---RTPPAIRRRSRSRTPLLPRKRSRSRSPLAIRRRSRSR-TPRTARGKRSLTRSPPAIR 2076
Query: 1835 SSGHSGSHHSHTTSQERSDVSRGQSGSRSVSRQTRNEKQSG-----------DGSRHSGS 1883
SGS + S +R SGSR+ + + S D R G
Sbjct: 2077 RRSASGSSSDRSRS-ATPPATRNHSGSRTPPVALNSSRMSCFSRPSMSPTPLDRCRSPGM 2135
Query: 1884 RHHEASSRADSSRHSQVGQG--QSSGPRTSRNQGSSVSQD 1921
SSR S Q G GPR +Q +SV ++
Sbjct: 2136 LEPLGSSRTPMSVLQQAGGSMMDGPGPRIPDHQRTSVPEN 2175
Score = 151 bits (382), Expect = 1e-35
Identities = 394/1858 (21%), Positives = 630/1858 (33%), Gaps = 199/1858 (10%)
Query: 2192 KTYDKEQSGDGSRHSGSHHHEASSWADSSRHSLVGQGQSSGPRTSRPRGSSVSQDSDSEG 2251
K Y + SR + D R S +SS PR R + SS + SE
Sbjct: 169 KPYSLVRESSSSRSPTPKQKKKKKKKDRGRRS-----ESSSPRRERKK-SSKKKKHRSES 222
Query: 2252 HSEDSERRSGS--ASRNHHGSAQEQSRDGSRHPRSHHEDRAGHGHSAESSRQSGTHHAEN 2309
S+ + RS + + R +++SR + P+S RA SA+S+ S T + +
Sbjct: 223 ESKKRKHRSPTPKSKRKSKDKKRKRSRSTTPAPKSR---RAHRSTSADSASSSDTSRSRS 279
Query: 2310 SSGGQAASSHEQARSSAGERHGSHHQQSADSSRHSGIGHGQASSAVRDSGHRGSSGSQAS 2369
S AA +H A + S + D+ +S R S ++ +S
Sbjct: 280 RSA--AAKTHTTALAGRSPSPASGRRGEGDAP----FSEPGTTSTQRPSSPETATKQPSS 333
Query: 2370 DSEGHSEDSDTQSVSAHGQAGPHQQSHQESTRGRSAGRSGRSGSFLYQVSTHEQSESAHG 2429
E +D +S + + P + S + + R G ++T S+
Sbjct: 334 PYEDKDKDKKEKSATRPSPS-PERSSTGPEPPAPTPLLAERHGGSPQPLATTPLSQEPVN 392
Query: 2430 RTGTSTGGRQGSHHKQARDSSRHSTSQEGQDTIHGHPGSSSGGRQGSHYEQLVDRSGHSG 2489
++ R S K + S+S+ + P + R S + + G
Sbjct: 393 PPSEASPTRDRSPPKSPEKLPQSSSSESSPPS----PQPTKVSRHASSSPESPKPAPAPG 448
Query: 2490 SHHSHTTSQGRSDASHGHSGSRSASRQTRNDEQSGDGSRHSGSRHHEASSRADSSGHSQV 2549
SH ++S + SHG + + T + S + R S GHS+
Sbjct: 449 SHREISSSPTSKNRSHGRAKRDKSHSHTPSRRMGRSRSPATAKRGRSRSRTPTKRGHSRS 508
Query: 2550 GQGQSEGPRTSRNWGSSFSQDSDSQGHSEDSERWSGSASRNHHGSAQEQLRDGSRHPRSH 2609
Q R+++ WG S S + S WS S + G ++ +R RSH
Sbjct: 509 RSPQWRRSRSAQRWGRSRSPQRRGRSRSPQRPGWSRSRNTQRRGRSR-----SARRGRSH 563
Query: 2610 QEDRAGHGHSADSSRQSGTRHTQTSSGGQAASSHEQARSSAGERHGSHHQQSADSSRHSG 2669
A G S SR R S + ++RS R S + A R
Sbjct: 564 SRSPATRGRS--RSRTPARRGRSRS----RTPARRRSRSRTPTRRRSRSRTPARRGRSRS 617
Query: 2670 IGHGQASSAVRDSGHRGYSGSQASDNEGHSEDSDTQSVSAHGQAGSHQQSHQESARGRS- 2728
+ S R R + G S +++ + G++ S + + +R R+
Sbjct: 618 RTPARRRSRTRSPVRRRSRSRSPARRSGRSR---SRTPARRGRSRSRTPARRGRSRSRTP 674
Query: 2729 GETSGHSGSFLYQVSTHEQSESSHGWTGPSTRGRQGSRHEQAQDSSRHSASQDGQDTIRG 2788
SG S S P+ RGR SR + S S + G+ R
Sbjct: 675 ARRSGRSRS-----------------RTPARRGRSRSRTPRRGRSRSRSLVRRGRSHSRT 717
Query: 2789 HPGSSRGGRQGYHHEHSVDSSGHSGSHHSHTTSQGR--SDASRGQSGSRSASRTTRNEEQ 2846
R G S S S S+ S + R S SR S RS +++ + +
Sbjct: 718 PQRRGRSGSSSERKNKSRTSQRRSRSNSSPEMKKSRISSRRSRSLSSPRSKAKSRLSLRR 777
Query: 2847 SGDGSRHSGSRHHEASTHADISRHSQAVQGQSEGSRRSRRQGSSVSQDSDSEGHSEDSER 2906
S GS + + S SQ RRSR SS S + + +
Sbjct: 778 SLSGSSPCPKQKSQTPPRRSRSGSSQPKAKSRTPPRRSR---SSSSPPPKQKSKTPSRQS 834
Query: 2907 WSGSASRNHHGSAQEQLRDGSRHPRSHQED-----RAGHGHSADSSRQSGTRHTQTSSGG 2961
S S+ S + P+++++ R+ S D +S T + SG
Sbjct: 835 HSSSSPHPKVKSGTPPRQGSITSPQANEQSVTPQRRSCFESSPDPELKSRTPSRHSCSG- 893
Query: 2962 QAASSHEQARSSAGERHGSHHQQSADSSRHSGIGHGQASSAVRDSGHRGYSGSQASDNEG 3021
SS + +SS R S + I Q S + S S+ +
Sbjct: 894 ---SSPPRVKSSTPPRQSPSRSSSPQPKVKAIISPRQRSHSGSSSPSPSRVTSRTTPRRS 950
Query: 3022 HSED--SDTQSVSAHGQAGSHQQSHQESARGRSGETSGHSGSFLYQVSTHEQSESSHGWT 3079
S S+ +S + S S + + HSGS Q+
Sbjct: 951 RSVSPCSNVESRLLPRYSHSGSSSPDTKVKPETPPRQSHSGSISPYPKVKAQTP-----P 1005
Query: 3080 GPSTRGRQGSRHEQAQDSSRHSASQY--GQDTIRGHPGSSRGGRQGYHHEHSVDSSGHSG 3137
GPS GS+ Q+ S+ S Q G ++ SS + Y S+ G S
Sbjct: 1006 GPSL---SGSKSPCPQEKSKDSLVQSCPGSLSLCAGVKSSTPPGESYFGVSSLQLKGQSQ 1062
Query: 3138 SHHSHTTSQGRSDASRGQSGSRSASRTTRNEEQSGDSSRHS-----VSRHHEASTHADIS 3192
+ H + + + S S S ++ + G S S SR + S
Sbjct: 1063 TSPDHRSDTSSPEVRQSHSESPSLQSKSQTSPKGGRSRSSSPVTELASRSPIRQDRGEFS 1122
Query: 3193 RHSQAVQGQS-EGSRRSRRQGSSVSQDSDS-EGHS-----EDSERWSGSASRNHRGSVQE 3245
G S E SR S + DS+S G S E E+ + + S
Sbjct: 1123 ASPMLKSGMSPEQSRFQSDSSSYPTVDSNSLLGQSRLETAESKEKMALPPQEDATASPPR 1182
Query: 3246 QSRHGSRHP---------------RSHHEDRAGHGHSADRSRQSGTRHAETSSGGQAASS 3290
Q S P R+ +R+G G S + Q+ TSS +
Sbjct: 1183 QKDKFSPFPVQDRPESSLVFKDTLRTPPRERSGAGSSPETKEQNSA--LPTSSQDEELME 1240
Query: 3291 HEQARSSPGER---HGSRHQQSADSSRHSGIPRGQASSAVRDSRHWGSSGSQASDSEGHS 3347
+ P + H S + +S P + AV S S SQAS E
Sbjct: 1241 VVEKSEEPAGQILSHLSSELKEMSTSNFESSPEVEERPAV--SLTLDQSQSQAS-LEAVE 1297
Query: 3348 EESDTQSVSGHGQAGPHQQSHQESARDRSGG------RSGRSGSFLYQVSTHEQSESAHG 3401
S S G + H++ R+ S G SG G+ + + E E +G
Sbjct: 1298 VPSMASSWGGPHFSPEHKELSNSPLRENSFGSPLEFRNSGPLGTEMNTGFSSEVKEDLNG 1357
Query: 3402 RTRTSTGRRQG-SHHEQARDSSRHSASQEGQDTIRGHPGSSRRGRQGSHYEQSVDRS--- 3457
EQ+ SS HS+S+ D + G S S +V R+
Sbjct: 1358 PFLNQLETDPSLDMKEQSTRSSGHSSSELSPDAVE-KAGMSSNQSISSPVLDAVPRTPSR 1416
Query: 3458 GHSGSHHSHTTSQG--RSDASRGQSGSRSASRQTRNDEQSGDGSRHSWSHHHEA-----S 3510
S S S G R+ + R +SGS R + SG SRHS S
Sbjct: 1417 ERSSSASSPEMKDGLPRTPSRRSRSGSSPGLR-----DGSGTPSRHSLSGSSPGMKDIPR 1471
Query: 3511 TQADSSRHSQSGQGQSAGPRTSRNQGSSVSQ-DSDSQGHSEDSERWSGSASRNHRGSAQ- 3568
T + S A P+T R + S S + +++ + ER +S + + A+
Sbjct: 1472 TPSRGRSECDSSPEPKALPQTPRPRSRSPSSPELNNKCLTPQRERSGSESSVDQKTVART 1531
Query: 3569 ---EQSRDGSRH-----PTSHHEDRAGHGHSAESSRQSGTHHAENSSGGQAASSHEQARS 3620
++SR GS P++ ++R+ S +S ++ T + S G + ++R
Sbjct: 1532 PLGQRSRSGSSQELDVKPSASPQERSESDSSPDSKAKTRTPLRQRSRSGSSPEVDSKSRL 1591
Query: 3621 SAGERHGSHHQQSADSSRHSGIGHGQASSAVRDSGHRGSSGSQASDSEGHSEDSDTQSVS 3680
S + D R + R SGS DS + +
Sbjct: 1592 SPRRSRSGSSPEVKDKPR---------------AAPRAQSGS----------DSSPEPKA 1626
Query: 3681 AHGQAGPHQQSHQESTRGRSAGRSGRSGSFLYQVSTHEQSESAHGRAG------PSTGGR 3734
+A P + S++GR G S + + S +S R G P T R
Sbjct: 1627 PAPRALPRRSRSGSSSKGRGPSPEGSSST---ESSPEHPPKSRTARRGSRSSPEPKTKSR 1683
Query: 3735 QGSRHEQARDS---SRHSASQEGQDTIRGHPGSRRGGRQGSYHEQSVDRSGHSGSHHSHT 3791
R +R S +R + + P +R R H +S S + S +
Sbjct: 1684 TPPRRRSSRSSPELTRKARLSRRSRSASSSPETR--SRTPPRHRRSPSVSSPEPAEKSRS 1741
Query: 3792 TSQGRSDASHGQSGSRSASRETRNEEQSGDGSRHSGSRHHEASTQADSSRHSQSGQGESA 3851
+ + RS +S +++ SR R+ G + S SR T+ + R +SG +S
Sbjct: 1742 SRRRRSASS---PRTKTTSRRGRSPSPKPRGLQRSRSRSRREKTRT-TRRRDRSGSSQST 1797
Query: 3852 GSRRSRRQGSS--VSQDSDSEAYPEDSERRSESASRNHHGSSREQSRDGSRHPGSSHRDT 3909
RR R + S + Y S R ES+ +S + R SR P +S + +
Sbjct: 1798 SRRRQRSRSRSRVTRRRRGGSGYHSRSPARQESSR-----TSSRRRRGRSRTPPTSRKRS 1852
Query: 3910 ASHVQSSPVQSDSSTAKEHGHFSSLSQDSAY-HSGIQSRGSPHSSSSYHYQSEGTERQ 3966
S +P + S A H S S+ +SR SP S ++ T R+
Sbjct: 1853 RSRTSPAPWKRSRSRASPATHRRSRSRTPLISRRRSRSRTSPVSRRRSRSRTSVTRRR 1910
Score = 140 bits (353), Expect = 3e-32
Identities = 474/2140 (22%), Positives = 742/2140 (34%), Gaps = 248/2140 (11%)
Query: 123 KRPSSLERRNNRKGNKGRSKSPRETGG------KRHESSSEKKERKGYSPTHREEEYGKN 176
+R S R R+ + RS++P G +R S S R+G S + + G++
Sbjct: 665 RRGRSRSRTPARRSGRSRSRTPARRGRSRSRTPRRGRSRSRSLVRRGRSHSRTPQRRGRS 724
Query: 177 HHNSSKKEKNKTENTRLGDNR--KRLSERLEEKEDNEEGVYDYENTGRMTQKWIQSGHIA 234
+S +K K++T R N + R+ + + R++ + SG
Sbjct: 725 GSSSERKNKSRTSQRRSRSNSSPEMKKSRISSRRSRSLSSPRSKAKSRLSLRRSLSG--- 781
Query: 235 TYYTIQDEAYDTTDSLLEENKIYERSRSSDGKSSSQVNRSRHENTSQVPLQESRTRKRRG 294
S + S KS + RSR ++S P Q+S+T R+
Sbjct: 782 ------SSPCPKQKSQTPPRRSRSGSSQPKAKSRTPPRRSR-SSSSPPPKQKSKTPSRQS 834
Query: 295 SRVSQDRDSEGHSEDSERHSGSASRNHHGSAWEQSR---DGSRHP--RSHDEDRASHGHS 349
S + S ++ + + S Q R + S P +S R S S
Sbjct: 835 HSSSSPHPKVKSGTPPRQGSITSPQANEQSVTPQRRSCFESSPDPELKSRTPSRHSCSGS 894
Query: 350 ADSSRQSGTRHAETSSRGQTASSHEQARSSPGERHGSGHQQSADSSRHSATG--RGQASS 407
+ +S T ++ SR + +A SP +R SG + S S T R ++ S
Sbjct: 895 SPPRVKSSTPPRQSPSRSSSPQPKVKAIISPRQRSHSGSSSPSPSRVTSRTTPRRSRSVS 954
Query: 408 AVSDRGHR-----GSSGSQASDSEGHSENSDTQSVSGHGKAGLRQQSHQESTRGRSGERS 462
S+ R SGS + D++ E QS SG + ++ SG +S
Sbjct: 955 PCSNVESRLLPRYSHSGSSSPDTKVKPETPPRQSHSGSISPYPKVKAQTPPGPSLSGSKS 1014
Query: 463 GRSGSSLYQVSTHEQPDSAHGRTGTSTGGRQGSHHEQARDSSRHSASQEGQDTIRGHPGS 522
P S G + G + SQ D H
Sbjct: 1015 PCPQEKSKDSLVQSCPGSLSLCAGVKSSTPPGESYFGVSSLQLKGQSQTSPD----HRSD 1070
Query: 523 SRGGRQGSHHEQSVNRSGHSGSHHSHTTSQGRSDASHGQSGSRSASRQTRNEEQSGDGTR 582
+ H +S S S S S + RS + + SRS RQ R E + +
Sbjct: 1071 TSSPEVRQSHSESP--SLQSKSQTSPKGGRSRSSSPVTELASRSPIRQDRGEFSASPMLK 1128
Query: 583 HSGSRHHEASSQADSSRHSQVGQGQSSGPRT-----SRNQGSSVSQDSDSQGHSEDSERW 637
SG ++ Q+DSS + V G S+ + + Q+ + +++
Sbjct: 1129 -SGMSPEQSRFQSDSSSYPTVDSNSLLGQSRLETAESKEKMALPPQEDATASPPRQKDKF 1187
Query: 638 SGSASRNHHGSAQEQSRDGSRHPRSHHEDRAGHGHSADSSRKSGTRHTQNSSSGQAASSH 697
S ++ S+ +D R P +R+G G S ++ ++ T +S +
Sbjct: 1188 SPFPVQDRPESSLV-FKDTLRTPP---RERSGAGSSPETKEQNSALPT-SSQDEELMEVV 1242
Query: 698 EQARSSAGE--RHGSRHQLQSADSSRHSGTGHGQASSAVRDSGHRGSSGSQATDSEGHSE 755
E++ AG+ H S +L+ +S + + AV S + S+ E
Sbjct: 1243 EKSEEPAGQILSHLSS-ELKEMSTSNFESSPEVEERPAV-------SLTLDQSQSQASLE 1294
Query: 756 DSDTQSVSGHGQAGHHQQSHQESARDRSGERS-------RRSGSFLYQVSTHKQSESSHG 808
+ S++ H H+E + E S R SG +++T SE
Sbjct: 1295 AVEVPSMASSWGGPHFSPEHKELSNSPLRENSFGSPLEFRNSGPLGTEMNTGFSSEVKED 1354
Query: 809 WTGPSTGVRQGSHH----EQARDNSRHSASQDGQDTIRGHPGSSRRGRQGSHHEQSVDRS 864
GP + EQ+ +S HS+S+ D + G S S +V R+
Sbjct: 1355 LNGPFLNQLETDPSLDMKEQSTRSSGHSSSELSPDAVE-KAGMSSNQSISSPVLDAVPRT 1413
Query: 865 G---HSGSHHSHTTSQG--RSDASRGQSGSRSASRTTRNEEQSRDGSRHSGSRHHEASSH 919
S S S G R+ + R +SGS R + S SRHS S +
Sbjct: 1414 PSRERSSSASSPEMKDGLPRTPSRRSRSGSSPGLR-----DGSGTPSRHSLSG--SSPGM 1466
Query: 920 ADISRHSQAGQGQSEGS-------RTSR-RQGSSVSQDSDSEGHSEDSERWSGSASRNHR 971
DI R G+ + + S +T R R S S + +++ + ER +S + +
Sbjct: 1467 KDIPRTPSRGRSECDSSPEPKALPQTPRPRSRSPSSPELNNKCLTPQRERSGSESSVDQK 1526
Query: 972 GSAQ----EQSRHGSRH-----PRSHHEDRAGHGHSADSSRQSGTPHAETSSGGQAASSH 1022
A+ ++SR GS P + ++R+ S DS ++ TP + S G +
Sbjct: 1527 TVARTPLGQRSRSGSSQELDVKPSASPQERSESDSSPDSKAKTRTPLRQRSRSGSSPEVD 1586
Query: 1023 EQARSSPGE-RHGS------------RHQQSADSSRHS------GIPRRQAS-SAVRDSG 1062
++R SP R GS R Q +DSS +PRR S S+ + G
Sbjct: 1587 SKSRLSPRRSRSGSSPEVKDKPRAAPRAQSGSDSSPEPKAPAPRALPRRSRSGSSSKGRG 1646
Query: 1063 HWGSSGSQASDSEGHSEESDTQSVSGHGQDGPHQQSHQESARDWSGGRSGRSGSFIYQ-- 1120
S S H +S T P +S R RS RS + +
Sbjct: 1647 PSPEGSSSTESSPEHPPKSRTARRGSRSSPEPKTKSRTPPRR-----RSSRSSPELTRKA 1701
Query: 1121 -VSTHEQSESAHGRTRTSTGRRQ----GSHHEQARDSSRHSASQEGQDTIRAHPGSRRGG 1175
+S +S S+ TR+ T R + + SR S + + R SRRG
Sbjct: 1702 RLSRRSRSASSSPETRSRTPPRHRRSPSVSSPEPAEKSRSSRRRRSASSPRTKTTSRRG- 1760
Query: 1176 RQGSHHEQSVDRSGHSGSHHSHTTSQGRSDASHGQSGSR------SASRQTRKDKQSGDG 1229
R S + + RS T++ R + QS SR S SR TR+ + G
Sbjct: 1761 RSPSPKPRGLQRSRSRSRREKTRTTRRRDRSGSSQSTSRRRQRSRSRSRVTRRRR--GGS 1818
Query: 1230 SRHSGSRHHEAASWADSSRHSQVGQEQSSGSRTSRHQGSSVSQDSDSERHSDDSERLSGS 1289
HS S + +S S R + + + SR + S R S + R S S
Sbjct: 1819 GYHSRSPARQESSRTSSRRRRGRSRTPPTSRKRSRSRTSPAPWKRSRSRASPATHRRSRS 1878
Query: 1290 A----SRNHHGS-----SREQSRDGSRHPGFHQEDRASH-GHSADSSRQSGTHHTESSSH 1339
SR S SR +SR + RAS SR S S
Sbjct: 1879 RTPLISRRRSRSRTSPVSRRRSRSRTSVTRRRSRSRASPVSRRRSRSRTPPVTRRRSRSR 1938
Query: 1340 GQAVSSHEQARSSPGERHGSRHQ-----QSADSSRHSGIGHRQASSAVRDSGHRGSSG-- 1392
++R+ P R SR + + SR S I R++ S R S
Sbjct: 1939 TPTTRRRSRSRTPPVTRRRSRSRTPPVTRRRSRSRTSPITRRRSRSRTSPVTRRRSRSRT 1998
Query: 1393 SQVTNSEGHSEDSDTQSVSAHGQAGPHQQSHKESARGQSGESSGRSRSFLYQVSSHEQSE 1452
S VT S S + + P + S RSRS L + +S
Sbjct: 1999 SPVTRRRSRSRTSPVTRRRSRSRTPPAIRRRSRSRTPLLPRKRSRSRSPL---AIRRRSR 2055
Query: 1453 STHGQTAPSTGGRQGSRHEQARNSSRHSASQDGQDTIRGH-PGSSRGGRQGSYHEQSVDR 1511
S +TA G R +R A R SAS D R P ++R +++
Sbjct: 2056 SRTPRTA--RGKRSLTRSPPAIR--RRSASGSSSDRSRSATPPATRNHSGSRTPPVALNS 2111
Query: 1512 SGHSGYHHSHTTPQGRSDA-SHGQSGPRSASRQTRNEEQSGDGS-------------RHS 1557
S S + +P S G P +SR + Q GS R S
Sbjct: 2112 SRMSCFSRPSMSPTPLDRCRSPGMLEPLGSSRTPMSVLQQAGGSMMDGPGPRIPDHQRTS 2171
Query: 1558 GSRHHEPSTRAGSSRHSQVGQGESAGSKTSRRQGSSVSQD---------RDSEGHSEDSE 1608
+H S A + +G S ++ + +SQ R + + S
Sbjct: 2172 VPENHAQSRIALALTAISLGTARPPPSMSAAGLAARMSQVPAPVPLMSLRTAPAANLASR 2231
Query: 1609 RRSESASRNHYGSAREQSRHGSRNPRSHQEDRASHGHSAESSRQSGTRHAETSSGGQAAS 1668
+ SA+ + SAR + + N + A+ + S R + A + + +
Sbjct: 2232 IPAASAAAMNLASARTPAIPTAVNLADSRTPAAAAAMNLASPRTAVAPSAVNLADPRTPT 2291
Query: 1669 SQEQARSSPGERHGSRHQQSADSSTDSGTGRRQDSSVVGDSGNRGSSGSQASDSEGHSEE 1728
+ A + G R + +A S T SGT ++ S +R +++ G
Sbjct: 2292 AP--AVNLAGARTPAA--LAALSLTGSGT---PPTAANYPSSSRTPQAPASANLVGPRSA 2344
Query: 1729 SDTQSVSAHGQ--AGPHQQSHQESTRGQSGERSGRSGSFLYQVSTHEQSESAHGRTGPST 1786
T V+ G A + S R S +S +E+ GRT P
Sbjct: 2345 HATAPVNIAGSRTAAALAPASLTSARMAPALSGANLTSPRVPLSAYER---VSGRTSPPL 2401
Query: 1787 GGRQRSRHEQARDSSRHSASQEGQDTIRGHPGSSRGGRQGSH------YEQSVDSSGHSG 1840
R RSR + S S+ R SSR G+ S +Q +
Sbjct: 2402 LDRARSRTPPSAPSQSRMTSE------RAPSPSSRMGQAPSQSLLPPAQDQPRSPVPSAF 2455
Query: 1841 SHHSHTTSQERSDVSRGQSGSRSVSRQTRNEKQSGD----------GSRHSGSRHHEASS 1890
S S + + V+ QS S T + +GD G HS AS+
Sbjct: 2456 SDQSRCLIAQTTPVAGSQSLSSGAVATTTSS--AGDHNGMLSVPAPGVPHSDVGEPPAST 2513
Query: 1891 RADSSRHSQVGQGQSSGPRTSRNQGSSVSQDSDSQGHSEDSERWSGSASRNHLGSAW--- 1947
A S + Q + R S + SS S S S S S SGS+S + GS+
Sbjct: 2514 GAQQP--SALAALQPAKERRSSSSSSSSSSSSSSSSSSSSSSSSSGSSSSDSEGSSLPVQ 2571
Query: 1948 ---EQSRDGSRHPGSHHEDRAGHGHS---ADSSRQSGTRHTESSSRGQAASSHEQARSSA 2001
R S P R G A R+S + + SSS ++SS + SS+
Sbjct: 2572 PEVALKRVPSPTPAPKEAVREGRPPEPTPAKRKRRSSSSSSSSSSSSSSSSSSSSSSSSS 2631
Query: 2002 GERHGSHHQLQSADSSRHSGIGHGQASSAVRDSGHRGYSGSQASDSEGHSEDS--DTQSV 2059
S S+ SS S G + S + G + S S DS D++S+
Sbjct: 2632 SSSSSSSSSSSSSSSSSPSPAKPGPQALPKPASPKKPPPGERRSRSPRKPIDSLRDSRSL 2691
Query: 2060 S--------AQGKAGPHQQ----SHKESARGQSGESSGRS 2087
S + P Q S + S RGQ G+S S
Sbjct: 2692 SYSPVERRRPSPQPSPRDQQSSSSERGSRRGQRGDSRSPS 2731
Score = 132 bits (332), Expect = 7e-30
Identities = 375/1733 (21%), Positives = 564/1733 (32%), Gaps = 227/1733 (13%)
Query: 2379 DTQSVSAHGQAGPHQQSHQESTRGRSAGRSGRSGSFLYQVSTHEQSESAHGRTGTSTGGR 2438
D S +A +Q E + S R S ++ + GR S+ R
Sbjct: 147 DGSSFDPQRRAREAKQPAPEPPKPYSLVRESSSSRSPTPKQKKKKKKKDRGRRSESSSPR 206
Query: 2439 QGSHHKQARDSSRHSTSQEGQDTIHGHPGSSSGGRQGSHYEQLVDRSG----HSGSHHSH 2494
+ K++ +H + E + H P S R+ ++ RS S H
Sbjct: 207 R--ERKKSSKKKKHRSESESKKRKHRSPTPKSK-RKSKDKKRKRSRSTTPAPKSRRAHRS 263
Query: 2495 TTSQGRSDASHGHSGSRSASRQTRNDEQSGDGSRHSGSRHHEASSRADSSGHSQVGQGQS 2554
T++ S + S SRSA+ +T +G + R E + G + + S
Sbjct: 264 TSADSASSSDTSRSRSRSAAAKTHTTALAGRSPSPASGRRGEGDAPFSEPGTTSTQRPSS 323
Query: 2555 EGPRTSRNWGSSFSQDSDSQGHSEDSERWSGSASRNHHGSAQEQLRD--GSRHPRSHQED 2612
P T+ SS +D D + + R S S R+ G RH S Q
Sbjct: 324 --PETATKQPSSPYEDKDKDKKEKSATRPSPSPERSSTGPEPPAPTPLLAERHGGSPQPL 381
Query: 2613 RAGHGHSADSSRQSGTRHTQTSSGGQAASSHEQARSSAGERHGSHHQQSADSSRHSGIGH 2672
+ S T+ S S E+ S+ Q SRH+
Sbjct: 382 ATTPLSQEPVNPPSEASPTRDRS---PPKSPEKLPQSSSSESSPPSPQPTKVSRHASSSP 438
Query: 2673 GQASSAVRDSGHRGYSGSQASDNEGHSEDSDTQSVS-----AHGQAGSHQQSHQESARGR 2727
A HR S S S N H +S S G++ S + + +R R
Sbjct: 439 ESPKPAPAPGSHREISSSPTSKNRSHGRAKRDKSHSHTPSRRMGRSRSPATAKRGRSRSR 498
Query: 2728 SGETSGHSGSFLYQVSTHEQSESSHGW---TGPSTRGRQGSRHEQAQDSSRHSASQDGQD 2784
+ GHS S Q +S S+ W P RGR S SR++ +
Sbjct: 499 TPTKRGHSRSRSPQ---WRRSRSAQRWGRSRSPQRRGRSRSPQRPGWSRSRNTQRR---- 551
Query: 2785 TIRGHPGSSRGGRQGYHHEHSVDSSGHS--------GSHHSHTT--------------SQ 2822
G SR R+G H S + G S G S T S+
Sbjct: 552 ------GRSRSARRGRSHSRSPATRGRSRSRTPARRGRSRSRTPARRRSRSRTPTRRRSR 605
Query: 2823 GRSDASRGQSGSRSASRT-------TRNEEQSGDGSRHSGSRHHEASTHADISR-HSQAV 2874
R+ A RG+S SR+ +R R +S +R SG SR + A
Sbjct: 606 SRTPARRGRSRSRTPARRRSRTRSPVRRRSRSRSPARRSGRSRSRTPARRGRSRSRTPAR 665
Query: 2875 QGQSEGSRRSRRQGSSVSQDSDSEGHSEDSERWSGSA--------SRNHHGSAQEQLRDG 2926
+G+S +RR G S S+ G S G + R+H + Q + R G
Sbjct: 666 RGRSRSRTPARRSGRSRSRTPARRGRSRSRTPRRGRSRSRSLVRRGRSHSRTPQRRGRSG 725
Query: 2927 SRHPR------SHQEDRAGHGHSADSSRQSGTRHTQTSSGGQAASSHEQARSSAGERHGS 2980
S R S + R+ SR S R SS A S R S
Sbjct: 726 SSSERKNKSRTSQRRSRSNSSPEMKKSRISSRRSRSLSSPRSKAKSRLSLRRSLSGSSPC 785
Query: 2981 HHQQSADSSRHSGIGHGQASSAVRDSGHRGYSGSQASDNEGHSEDSDTQSVSAHGQAGSH 3040
Q+S R S G Q + R R S++S + + S T S +H + H
Sbjct: 786 PKQKSQTPPRRSRSGSSQPKAKSRTPPRR----SRSSSSPPPKQKSKTPSRQSHSSSSPH 841
Query: 3041 QQSHQESARGRSGETSGHSGSFLYQVSTHEQSESSHGWTGPSTRGRQGSRHEQAQDSSRH 3100
+ + + TS + Q T ++ P + R SRH + S
Sbjct: 842 PKVKSGTPPRQGSITSPQANE---QSVTPQRRSCFESSPDPELKSRTPSRHSCSGSSPPR 898
Query: 3101 SASQYGQDTIRGHPGSSRGGRQGYHHEHSVDSSGHSGSHHSHTTSQGRSDASRG------ 3154
S S + + SG S S TS+ SR
Sbjct: 899 VKSSTPPRQSPSRSSSPQPKVKAIISPRQRSHSGSSSPSPSRVTSRTTPRRSRSVSPCSN 958
Query: 3155 ----------QSGSRSASRTTRNEEQSGDSSRHSVSRHHE--ASTHADISRHSQAVQGQS 3202
SGS S + E S S+S + + A T S
Sbjct: 959 VESRLLPRYSHSGSSSPDTKVKPETPPRQSHSGSISPYPKVKAQTPPGPSLSGSKSPCPQ 1018
Query: 3203 EGSRRSRRQG--SSVSQDSDSEGHSEDSERWSGSASRNHRGSVQEQSRHGSRHPRSHHED 3260
E S+ S Q S+S + + + E + G +S +G Q H R S E
Sbjct: 1019 EKSKDSLVQSCPGSLSLCAGVKSSTPPGESYFGVSSLQLKGQSQTSPDH--RSDTSSPEV 1076
Query: 3261 RAGHGHSADRSRQSGTRHAETSSGGQAASSHEQARSSPGERHGSRHQQSADSSRHSGIPR 3320
R H S +S T + GG++ SS SP SR D S P
Sbjct: 1077 RQSHSESPSLQSKSQT----SPKGGRSRSS------SPVTELASRSPIRQDRGEFSASPM 1126
Query: 3321 GQASSAVRDSRHWGSSGSQAS-DSEGHSEESDTQSV-SGHGQAGPHQQSHQESA---RDR 3375
++ + SR S S + DS +S ++ S A P Q+ S +D+
Sbjct: 1127 LKSGMSPEQSRFQSDSSSYPTVDSNSLLGQSRLETAESKEKMALPPQEDATASPPRQKDK 1186
Query: 3376 SG-----GRSGRSGSFLYQVSTHEQSESAHGRTRTSTGRRQG----SHHEQARDSSRHSA 3426
R S F + T + S G + + + S E+ + S
Sbjct: 1187 FSPFPVQDRPESSLVFKDTLRTPPRERSGAGSSPETKEQNSALPTSSQDEELMEVVEKSE 1246
Query: 3427 SQEGQDTIRGHPGSSRRGRQGSHYEQSVDRSGHSGSHHSHTTSQGRSDASRGQSGSRSAS 3486
GQ I H S + S++E S + S T Q +S AS +
Sbjct: 1247 EPAGQ--ILSHLSSELKEMSTSNFESSPEVEERPAV--SLTLDQSQSQASL-------EA 1295
Query: 3487 RQTRNDEQSGDGSRHSWSHHHEASTQADSSRHSQSGQGQSAGPR-TSRNQGSSVSQDSDS 3545
+ + S G S H +++ + + +++GP T N G S D
Sbjct: 1296 VEVPSMASSWGGPHFSPEHKELSNSPLRENSFGSPLEFRNSGPLGTEMNTGFSSEVKEDL 1355
Query: 3546 QGH-------------SEDSERWSGSASRNHRGSAQEQSRDGSRHPTSHHE-DRAGHGHS 3591
G E S R SG +S A E++ S S D S
Sbjct: 1356 NGPFLNQLETDPSLDMKEQSTRSSGHSSSELSPDAVEKAGMSSNQSISSPVLDAVPRTPS 1415
Query: 3592 AESSRQSGTHHAENSSG-GQAASSHEQARSSAGERHGSHHQQSADSSRHSGIGHGQASSA 3650
E R S E G + S ++ SS G R GS SRHS G
Sbjct: 1416 RE--RSSSASSPEMKDGLPRTPSRRSRSGSSPGLRDGS-----GTPSRHSLSGSSPGMKD 1468
Query: 3651 VRDSGHRGSSGSQASDS-------------EGHSEDSDTQSVSAHGQAGPHQQSHQESTR 3697
+ + RG S +S S + + + ++ + + S + T
Sbjct: 1469 IPRTPSRGRSECDSSPEPKALPQTPRPRSRSPSSPELNNKCLTPQRERSGSESSVDQKTV 1528
Query: 3698 GRSA-GRSGRSGSFLY-----QVSTHEQSESAHGRAGPSTGGRQGSRHEQARDSSRHSAS 3751
R+ G+ RSGS S E+SES S+ + R SR +S
Sbjct: 1529 ARTPLGQRSRSGSSQELDVKPSASPQERSES------DSSPDSKAKTRTPLRQRSRSGSS 1582
Query: 3752 QEGQDTIRGHPGSRRGGRQGSYHEQSVDRSGHSGSHHSHTTSQGRSDASHGQSGSRS--- 3808
E R P R G ++ A QSGS S
Sbjct: 1583 PEVDSKSRLSPRRSRSGSSPEVKDKP-------------------RAAPRAQSGSDSSPE 1623
Query: 3809 ----ASRETRNEEQSGDGSRHSGSRHHEASTQADSSRHSQSGQGESAGSRRS---RRQGS 3861
A R +SG S+ G +S+ S H + GSR S + +
Sbjct: 1624 PKAPAPRALPRRSRSGSSSKGRGPSPEGSSSTESSPEHPPKSRTARRGSRSSPEPKTKSR 1683
Query: 3862 SVSQDSDSEAYPEDSERRSESASRNHHGSSREQSRDGSRHPGSSHRDTASHVQSSPVQSD 3921
+ + S + PE R++ + R+ SS ++R SR P HR + S P +
Sbjct: 1684 TPPRRRSSRSSPE-LTRKARLSRRSRSASSSPETR--SRTP-PRHRRSPSVSSPEPAEKS 1739
Query: 3922 SSTAKEHGHFSSLSQDSAYHSGIQS---RGSPHSSSSYHYQSEGTERQKGQSG 3971
S+ + S ++ ++ S RG S S + T R++ +SG
Sbjct: 1740 RSSRRRRSASSPRTKTTSRRGRSPSPKPRGLQRSRSRSRREKTRTTRRRDRSG 1792
Score = 48.1 bits (113), Expect = 2e-04
Identities = 57/221 (25%), Positives = 81/221 (36%), Gaps = 29/221 (13%)
Query: 394 SSRHSATGRGQASSAVSDRGHRGSSGSQASDSEGHSENSDTQ-------SVSGHGKAGLR 446
SS S++ +SS+ S SSGS +SDSEG S + S + K +R
Sbjct: 2532 SSSSSSSSSSSSSSSSSSSSSSSSSGSSSSDSEGSSLPVQPEVALKRVPSPTPAPKEAVR 2591
Query: 447 QQSHQESTRGRSGERSGRSGSSLYQVSTHEQPDSAHGRTGTSTGGRQGSHHEQARDSSRH 506
+ E T + RS S SS S+ S+ + +S+ S + SS
Sbjct: 2592 EGRPPEPTPAKRKRRSSSSSSS--SSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSP 2649
Query: 507 SASQEGQDTI-------RGHPG------------SSRGGRQGSHHEQSVNRSGHSGSHHS 547
S ++ G + + PG S R R S+ R S
Sbjct: 2650 SPAKPGPQALPKPASPKKPPPGERRSRSPRKPIDSLRDSRSLSYSPVERRRPSPQPSPRD 2709
Query: 548 HTTSQGRSDASHGQSG-SRSASRQTRNEEQSGDGTRHSGSR 587
+S + GQ G SRS S + R E S RH SR
Sbjct: 2710 QQSSSSERGSRRGQRGDSRSPSHKRRRETPSPRPMRHRSSR 2750
Score = 45.8 bits (107), Expect = 9e-04
Identities = 65/269 (24%), Positives = 98/269 (36%), Gaps = 30/269 (11%)
Query: 993 AGHGHSADSSRQSGTPHAETSSGGQAASSHEQARSSPGERHGSRHQQSADSSRHSGIPRR 1052
AG + S G PH++ G AS+ Q S+ ++ ++S+ SS S
Sbjct: 2487 AGDHNGMLSVPAPGVPHSDV--GEPPASTGAQQPSALAALQPAKERRSSSSSSSSSSSSS 2544
Query: 1053 QASSAVRDSGHWGSSGSQASDSEGHS-----------EESDTQSVSGHGQDG-PHQQSHQ 1100
+SS+ S SSGS +SDSEG S S T + ++G P + +
Sbjct: 2545 SSSSSSSSSS---SSGSSSSDSEGSSLPVQPEVALKRVPSPTPAPKEAVREGRPPEPTPA 2601
Query: 1101 ESARDWSGGRSGRSGSFIYQVSTHEQSESAHGRTRTSTGRRQGSHHEQARDSSRHSASQE 1160
+ R S S S S S+ S S+ + +S+ S + A +
Sbjct: 2602 KRKRRSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSPSPAKPGPQALPK 2661
Query: 1161 GQDTIRAHPGSRRG------------GRQGSHHEQSVDRSGHSGSHHSHTTSQGRSDASH 1208
+ PG RR R S+ R S +S +
Sbjct: 2662 PASPKKPPPGERRSRSPRKPIDSLRDSRSLSYSPVERRRPSPQPSPRDQQSSSSERGSRR 2721
Query: 1209 GQSG-SRSASRQTRKDKQSGDGSRHSGSR 1236
GQ G SRS S + R++ S RH SR
Sbjct: 2722 GQRGDSRSPSHKRRRETPSPRPMRHRSSR 2750
Score = 45.4 bits (106), Expect = 0.001
Identities = 92/388 (23%), Positives = 138/388 (35%), Gaps = 52/388 (13%)
Query: 1263 SRHQGSSVSQDS-DSERHSDDSERLSGSASRNHHGSSREQSRDGSRHPGFHQEDRASHGH 1321
SR S+ SQ SER S R+ + S++ +++Q R F + R
Sbjct: 2407 SRTPPSAPSQSRMTSERAPSPSSRMGQAPSQSLLPPAQDQPRSPVPS-AFSDQSRCLIAQ 2465
Query: 1322 SA----DSSRQSGTHHTESSSHGQAVSSHEQARSSPGERHGSRHQQSADSSRHSGIGHRQ 1377
+ S SG T +SS G H S P G H + +G
Sbjct: 2466 TTPVAGSQSLSSGAVATTTSSAGD----HNGMLSVPAP--GVPHSDVGEPPASTGAQQPS 2519
Query: 1378 ASSAVRDSGHRGSSGSQVTNSEGHSEDSDTQSVSAHGQAGPHQQSHKESARGQSGESSGR 1437
A +A++ + R SS S ++S S S + S S+ S+ S +S G
Sbjct: 2520 ALAALQPAKERRSSSSSSSSSSSSSSSSSSSSSSS-------------SSGSSSSDSEGS 2566
Query: 1438 SRSFLYQVSSHEQSESTHGQTAPSTGGRQGSRHEQ--ARNSSRHSASQDGQDTIRGHPGS 1495
S +V+ T AP R+G E A+ R S+S S
Sbjct: 2567 SLPVQPEVALKRVPSPT---PAPKEAVREGRPPEPTPAKRKRRSSSSSSS---------S 2614
Query: 1496 SRGGRQGSYHEQSVDRSGHSGYHHSHTTPQGRSDASHGQSGPRSASRQTRNEEQSGDGSR 1555
S S S S S S ++ S S + GP++ + + ++ G R
Sbjct: 2615 SSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSPSPAKPGPQALPKPA-SPKKPPPGER 2673
Query: 1556 HSGSRHHEPSTRAGSSRHSQVGQGESAGSKTSRRQGSSVSQDRDSEGHSEDSERRSESAS 1615
S S P S R S+ + S RR+ S RD + S SER S
Sbjct: 2674 RSRS----PRKPIDSLRDSR----SLSYSPVERRRPSPQPSPRDQQ--SSSSERGSRRGQ 2723
Query: 1616 RNHYGSAREQSRHGSRNPRS--HQEDRA 1641
R S + R + +PR H+ R+
Sbjct: 2724 RGDSRSPSHKRRRETPSPRPMRHRSSRS 2751
Score = 42.7 bits (99), Expect = 0.007
Identities = 68/286 (23%), Positives = 105/286 (36%), Gaps = 33/286 (11%)
Query: 3659 SSGSQASDSEGHSEDSDTQSVSAHGQAGPHQQSHQESTRGRSAGRSGRSGSFLYQVSTHE 3718
SSG+ A+ + + + SV A G PH + S G S Q +
Sbjct: 2476 SSGAVATTTSSAGDHNGMLSVPAPGV--PHSDVGEPPA---STGAQQPSALAALQPAKER 2530
Query: 3719 QSESAHGRAGPSTGGRQGSRHEQARDSSRHSASQEGQDTIRGH----------PGSRRGG 3768
+S S+ + S+ S + S S S+ ++ P +
Sbjct: 2531 RSSSSSSSSSSSSSSSSSSSSSSSSSGSSSSDSEGSSLPVQPEVALKRVPSPTPAPKEAV 2590
Query: 3769 RQGSYHEQSVDRSGHSGSHHSHTTSQGRSDASHGQSGSRSASRETRNEEQSGDGSRHSGS 3828
R+G E + + S S ++S S +S S S S+S + + S S S S
Sbjct: 2591 REGRPPEPTPAKRKRRSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSPS 2650
Query: 3829 RHHEASTQADSSRHSQSGQGESAGSRRSR--RQGSSVSQDSDSEAY---------PEDSE 3877
A + S + G RRSR R+ +DS S +Y P+ S
Sbjct: 2651 ---PAKPGPQALPKPASPKKPPPGERRSRSPRKPIDSLRDSRSLSYSPVERRRPSPQPSP 2707
Query: 3878 RRSESASRNHHGSSREQSRDGSRHPGSSHRDTASHVQSSPVQSDSS 3923
R +S+S + GS R Q R SR P SH+ P++ SS
Sbjct: 2708 RDQQSSS-SERGSRRGQ-RGDSRSP--SHKRRRETPSPRPMRHRSS 2749
Score = 42.4 bits (98), Expect = 0.009
Identities = 77/352 (21%), Positives = 122/352 (34%), Gaps = 31/352 (8%)
Query: 1974 SRQSGTRHTESSSR-GQAAS------SHEQARSSAGERHGSHHQLQSADSSRHSG---IG 2023
SR + R SSR GQA S + +Q RS + A ++ +G +
Sbjct: 2417 SRMTSERAPSPSSRMGQAPSQSLLPPAQDQPRSPVPSAFSDQSRCLIAQTTPVAGSQSLS 2476
Query: 2024 HGQASSAVRDSGHRGYSGSQASDSEGHSEDSDTQSVSAQGKAGPHQQSHKESARGQSGES 2083
G ++ +G S + HS+ + + + G P + + A+ + S
Sbjct: 2477 SGAVATTTSSAGDHNGMLSVPAPGVPHSDVGEPPA--STGAQQPSALAALQPAKERRSSS 2534
Query: 2084 SGRSGSFLYQVSTHEQSESTHGQSAPSTGGRQGSHYDQAQDSSRHSASQEGQDTIRGH-P 2142
S S S S S+ S+ S+ GS ++ SS + + P
Sbjct: 2535 SSSSSS----------SSSSSSSSSSSSSSSSGSSSSDSEGSSLPVQPEVALKRVPSPTP 2584
Query: 2143 GPSRGGRQGSHQEQSV---DRSGHSGSHHSHTTSQGRSDASRGQSGSRSASRKTYDKEQS 2199
P R+G E + R S S S ++S S +S S S S+S + S
Sbjct: 2585 APKEAVREGRPPEPTPAKRKRRSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2644
Query: 2200 GDGSRHSGSHHHEASSWADSSRHSLVGQGQSSGPRTSRPRGSSVSQDSDSEGHSEDSERR 2259
S +A S + G+ +S PR +P S +DS S +S ERR
Sbjct: 2645 SSSSPSPAKPGPQALPKPASPKKPPPGERRSRSPR--KPIDS--LRDSRSLSYS-PVERR 2699
Query: 2260 SGSASRNHHGSAQEQSRDGSRHPRSHHEDRAGHGHSAESSRQSGTHHAENSS 2311
S + S GSR + H E+ H + S
Sbjct: 2700 RPSPQPSPRDQQSSSSERGSRRGQRGDSRSPSHKRRRETPSPRPMRHRSSRS 2751
Score = 40.8 bits (94), Expect = 0.028
Identities = 99/446 (22%), Positives = 151/446 (33%), Gaps = 61/446 (13%)
Query: 518 GHPGSSRGGRQGSHHEQSVNRSGHSGSHHSHTTSQGRSDASHGQSGSRSASRQTRNEEQS 577
G P ++ S Q+ + G +H T+ S + AS + +
Sbjct: 2315 GTPPTAANYPSSSRTPQAPASANLVGPRSAHATAPVNIAGSRTAAALAPASLTSARMAPA 2374
Query: 578 GDGTRHSGSRHHEASSQADSSRHSQ--VGQGQSSGPRTSRNQGSSVSQDSDSQGHSEDSE 635
G + R ++ + S R S + + +S P ++ +Q S+ + S S
Sbjct: 2375 LSGANLTSPRVPLSAYERVSGRTSPPLLDRARSRTPPSAPSQSRMTSERAPSP-----SS 2429
Query: 636 RWSGSASRNHHGSAQEQSR--------DGSRHPRSHHEDRAGHGHSADSSRKSGTRHTQN 687
R + S++ AQ+Q R D SR + AG S SG T
Sbjct: 2430 RMGQAPSQSLLPPAQDQPRSPVPSAFSDQSRCLIAQTTPVAG-----SQSLSSGAVATTT 2484
Query: 688 SSSGQA-------------ASSHEQARSSAGERHGSRHQLQSAD---SSRHSGTGHGQAS 731
SS+G + E S+ ++ + LQ A SS S + +S
Sbjct: 2485 SSAGDHNGMLSVPAPGVPHSDVGEPPASTGAQQPSALAALQPAKERRSSSSSSSSSSSSS 2544
Query: 732 SAVRDSGHRGSSGSQATDSEGHS----EDSDTQSVSGHGQAGHHQQSHQESARDRSGERS 787
S+ S SSGS ++DSEG S + + V A +R
Sbjct: 2545 SSSSSSSSSSSSGSSSSDSEGSSLPVQPEVALKRVPSPTPAPKEAVREGRPPEPTPAKRK 2604
Query: 788 RRSGSFLYQVSTHKQSESSHGWTGPSTGVRQGSHHEQARDNSRH-SASQDGQDTI----- 841
RRS S S+ S SS + S+ S + +S S ++ G +
Sbjct: 2605 RRSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSPSPAKPGPQALPKPAS 2664
Query: 842 --RGHPG------------SSRRGRQGSHHEQSVDRSGHSGSHHSHTTSQGRSDASRGQS 887
+ PG S R R S+ R S +S + RGQ
Sbjct: 2665 PKKPPPGERRSRSPRKPIDSLRDSRSLSYSPVERRRPSPQPSPRDQQSSSSERGSRRGQR 2724
Query: 888 G-SRSASRTTRNEEQSRDGSRHSGSR 912
G SRS S R E S RH SR
Sbjct: 2725 GDSRSPSHKRRRETPSPRPMRHRSSR 2750
Score = 39.7 bits (91), Expect = 0.062
Identities = 49/201 (24%), Positives = 67/201 (33%), Gaps = 30/201 (14%)
Query: 260 SRSSDGKSSSQVNRSRHENTSQVPLQESRTRKRRGSRVSQDRDSEGHSEDSERHSGSASR 319
S SS SSS + S S +P+Q KR S +++ E R
Sbjct: 2546 SSSSSSSSSSSGSSSSDSEGSSLPVQPEVALKRVPSPTPAPKEAVREGRPPEPTPAKRKR 2605
Query: 320 NHHGSAWEQSRDGSRHPRSHDEDRASHGHSADSSRQSGTRHAETSSRGQTASSHEQA--- 376
S+ S S S +S S+ SS S + + +SS A QA
Sbjct: 2606 RSSSSSSSSSSSSS----SSSSSSSSSSSSSSSSSSSSSSSSSSSSSPSPAKPGPQALPK 2661
Query: 377 -----RSSPGERHGSGHQQSADSSRHS----------------ATGRGQASSAVSDRGHR 415
+ PGER ++ DS R S + R Q SS+ R
Sbjct: 2662 PASPKKPPPGERRSRSPRKPIDSLRDSRSLSYSPVERRRPSPQPSPRDQQSSSSERGSRR 2721
Query: 416 GSSGSQASDSEGHSENSDTQS 436
G G S S H +T S
Sbjct: 2722 GQRGDSRSPS--HKRRRETPS 2740
>gi|171916097 repetin [Homo sapiens]
Length = 784
Score = 175 bits (443), Expect = 9e-43
Identities = 193/822 (23%), Positives = 314/822 (38%), Gaps = 101/822 (12%)
Query: 1 MSTLLENIFAIINLFKQYSKKDKNTDTLSKKELKELLEKEFRQILKNPDDPDMVDVFMDH 60
M+ LL +I ++I++F +Y+K + + L K+ELK+LL EF IL+ P+DP+ V+ ++
Sbjct: 1 MAQLLNSILSVIDVFHKYAKGNGDCALLCKEELKQLLLAEFGDILQRPNDPETVETILNL 60
Query: 61 LDIDHNKKIDFTEFLLMVFKLAQAYYESTRKENLPISGHKHRKHSHHDK-HEDNKQEENK 119
LD D + IDF E+LL+VF+L QA Y HK SH + + + +E
Sbjct: 61 LDQDRDGHIDFHEYLLLVFQLVQACY------------HKLDNKSHGGRTSQQERGQEGA 108
Query: 120 ENRKRPSSLERRNNRKGNKGRSKS----PRETGGKRHESSSEKKERKGYSPTHREEEYGK 175
++ K P + R++ ++ + R S P G H E+++R + +++
Sbjct: 109 QDCKFPGNTGRQHRQRHEEERQNSHHSQPERQDGDSHHGQPERQDRDSHHGQSEKQDRDS 168
Query: 176 NHHNSSKKEKNKTEN-TRLGDNRKRLSERLEEKEDNEEGVYDYENTGRMTQKWIQSGHIA 234
+H +++++ N + D + + +D+ G + KW GHI
Sbjct: 169 HHSQPERQDRDSHHNQSERQDKDFSFDQSERQSQDSSSGKKVSHKSTSGQAKW--QGHIF 226
Query: 235 TY----YTIQDEAYDTTDSLLEENKIYERSRSSDGKSSSQVNRSRHENTSQVPLQESRTR 290
IQD Y ++ ++++ + +S N++ + + Q R
Sbjct: 227 ALNRCEKPIQDSHYGQSERHTQQSETLGQ--------ASHFNQTNQQKSGSYCGQSERLG 278
Query: 291 KRRGSRVSQDRDSEGH-----SEDSERHSGSASRNHHGSAWEQS-RDGSRHPRSHDEDRA 344
+ G + + H +D H G R S + Q+ R G S + +
Sbjct: 279 QELGCGQTDRQGQSSHYGQTDRQDQSYHYGQTDRQGQSSHYSQTDRQGQSSHYSQPDRQG 338
Query: 345 SHGHSADSSRQSGTRHAETSSRGQTASSHEQARSSPGERHGSGHQQSADSSRH-SATGRG 403
H R+ H + ++R Q SH + G+ G + D S H T R
Sbjct: 339 QSSHYGQMDRKGQCYHYDQTNR-QGQGSHYSQPNRQGQSSHYGQPDTQDQSSHYGQTDRQ 397
Query: 404 QASSAVSDRGHRGSSGSQASDSEGHSENSDTQSVSGH-GKAGLRQQSHQESTRGRSGERS 462
SS H G + Q S H D Q H G+ + QS R G+ S
Sbjct: 398 DQSS------HYGQTERQGQSS--HYSQMDRQGQGSHYGQTDRQGQSSHYGQPDRQGQNS 449
Query: 463 -----GRSGSSLYQVSTHEQPDSAHGRTGTSTGGRQGSHHEQ--ARDSSRHSASQEGQDT 515
R G S + T Q S+H G Q SH+ + +D S H +GQ
Sbjct: 450 HYGQTDRQGQSSHYGQTDRQGQSSHYSQPDKQG--QSSHYGKIDRQDQSYHYGQPDGQGQ 507
Query: 516 IRGHPGSSRGG---------RQG-SHHEQSVNRSGHSGSHHSHTTSQGRSDASHGQS--- 562
+ + R G RQG S H ++R G S SH+ T QG+S + +GQ+
Sbjct: 508 SSHYGQTDRQGQSFHYGQPDRQGQSSHYSQMDRQGQS-SHYGQTDRQGQS-SHYGQTDRQ 565
Query: 563 ------------GSRSASRQTRNEEQSGDGTRHSGSRHHEASSQADSSRHSQVGQGQSSG 610
G S Q++ E G G+ +S + S S Q+ G
Sbjct: 566 GQSYHYGQTDRQGQSSHYIQSQTGEIQGQNKYFQGTEGTRKASYVEQSGRSGRLSQQTPG 625
Query: 611 PRTSRNQGSSV-SQDSDSQGHSEDSERWSGSASRNHHG----SAQEQSRDGSRHPRSHHE 665
+NQG S+DS GH + W HH + +Q R R
Sbjct: 626 QEGYQNQGQGFQSRDSQQNGH----QVWEPEEDSQHHQHKLLAQIQQERPLCHKGRDWQS 681
Query: 666 DRAGHGHSADSSRKS---GTRHTQNSSSGQAA---SSHEQARSSAGERHGSRHQLQSADS 719
+ GH +R+S G H G SHE G + H+ +
Sbjct: 682 CSSEQGHRQAQTRQSHGEGLSHWAEEEQGHQTWDRHSHESQEGPCGTQDRRTHKDEQNHQ 741
Query: 720 SRHSGTGHGQASSAVRD-SGHRGSSGSQATDSEGHSEDSDTQ 760
R T + S RD H Q D + H ++ + Q
Sbjct: 742 RRDRQTHEHEQSHQRRDRQTHEDKQNRQRRDRQTHEDEQNHQ 783
Score = 150 bits (380), Expect = 2e-35
Identities = 177/729 (24%), Positives = 275/729 (37%), Gaps = 72/729 (9%)
Query: 306 HSEDSERHSGSASRNHHGSAWEQS-----RDGSRHPRSHDEDRASHGHSADSSRQSGTRH 360
H D++ H G S+ G Q G +H + H+E+R + HS RQ G H
Sbjct: 87 HKLDNKSHGGRTSQQERGQEGAQDCKFPGNTGRQHRQRHEEERQNSHHS-QPERQDGDSH 145
Query: 361 AETSSRGQTASSHEQARSSPGERHGSGHQQSADSSRHSATGRGQASSAVSDRGHRGSSGS 420
R S H Q+ + H S ++ S H+ + R Q D+ R S S
Sbjct: 146 HGQPERQDRDSHHGQSEKQDRDSHHSQPERQDRDSHHNQSER-QDKDFSFDQSERQSQDS 204
Query: 421 QASDSEGHSENSDTQSVSGHGKAGLR-QQSHQESTRGRSGERSGRSGSSLYQVS----TH 475
+ H S GH A R ++ Q+S G+S ER + +L Q S T+
Sbjct: 205 SSGKKVSHKSTSGQAKWQGHIFALNRCEKPIQDSHYGQS-ERHTQQSETLGQASHFNQTN 263
Query: 476 EQPDSAHGRTGTSTGGRQGSHHEQARDSSRHSASQEGQDTIRGHPGSSRGGRQGSHHEQS 535
+Q ++ G G + S H + QD + + R G Q SH+ Q+
Sbjct: 264 QQKSGSYCGQSERLGQELGCGQTDRQGQSSHYGQTDRQDQSYHYGQTDRQG-QSSHYSQT 322
Query: 536 VNRSGHSGSHHSHTTSQGRSDASHGQSGSRSASRQTRNEEQSGDGTRHSGSRHHEASSQA 595
+R G S SH+S QG+S + +GQ + + G G+ +S + + Q
Sbjct: 323 -DRQGQS-SHYSQPDRQGQS-SHYGQMDRKGQCYHYDQTNRQGQGSHYS-----QPNRQG 374
Query: 596 DSSRHSQVG-QGQSSG-PRTSRNQGSSVSQDSDSQGHSEDSERWSGSASRNHHGSAQEQS 653
SS + Q Q QSS +T R SS ++ QG S + +H+G Q
Sbjct: 375 QSSHYGQPDTQDQSSHYGQTDRQDQSSHYGQTERQGQSSHYSQMDRQGQGSHYGQTDRQG 434
Query: 654 RDGSRHPRSHH--EDRAGHGHSADSSRKSGTRHTQNSSSGQAASSHEQARSSAGERHGSR 711
+ SH+ DR G + + G + Q SSH G+ S
Sbjct: 435 QS------SHYGQPDRQGQNSHYGQTDRQGQSSHYGQTDRQGQSSHYSQPDKQGQ---SS 485
Query: 712 H--QLQSADSSRHSGTGHGQASSA-------VRDSGHRGSSGSQATDSEGHSEDSDTQSV 762
H ++ D S H G GQ S+ S H G Q S H D Q
Sbjct: 486 HYGKIDRQDQSYHYGQPDGQGQSSHYGQTDRQGQSFHYGQPDRQGQSS--HYSQMDRQGQ 543
Query: 763 SGH-------GQAGHHQQSHQESARDRSGERSRRSGSFLYQVSTHKQSESSHGWTGPSTG 815
S H GQ+ H+ Q+ ++ G+ R+ S Y S + + + + + G
Sbjct: 544 SSHYGQTDRQGQSSHYGQTDRQGQSYHYGQTDRQGQSSHYIQSQTGEIQGQNKYFQGTEG 603
Query: 816 VRQGSHHEQARDNSRHSASQDGQDTIRGHPGSSRRGRQGSHHEQSVDRSGHSGSHHSH-- 873
R+ S+ EQ+ + R S GQ+ + + G + R + V HH H
Sbjct: 604 TRKASYVEQSGRSGRLSQQTPGQEGYQ-NQGQGFQSRDSQQNGHQVWEPEEDSQHHQHKL 662
Query: 874 --TTSQGRSDASRGQSGSRSASRTTRNEEQSRDGSRHSGSRH--HEASSHADISRH---S 926
Q R +G+ +S + Q+R S G H E H RH S
Sbjct: 663 LAQIQQERPLCHKGRDWQSCSSEQGHRQAQTRQ-SHGEGLSHWAEEEQGHQTWDRHSHES 721
Query: 927 QAGQGQSEGSRTSRRQGSSVSQDSDSEGHSEDSERWSGSASRNHRGSAQEQSRHGSRHPR 986
Q G ++ RT + + + +D + H + +R R+ + +Q+R R R
Sbjct: 722 QEGPCGTQDRRTHKDEQNHQRRDRQTHEHEQSHQR------RDRQTHEDKQNR--QRRDR 773
Query: 987 SHHEDRAGH 995
HED H
Sbjct: 774 QTHEDEQNH 782
Score = 149 bits (375), Expect = 7e-35
Identities = 203/795 (25%), Positives = 294/795 (36%), Gaps = 131/795 (16%)
Query: 469 LYQVSTHEQPDSAHG-RTGTSTGGRQGSHHEQARDSSRHSASQEGQDTIRGHPGSSRGGR 527
L Q H+ + +HG RT G++G A+D +T R H R
Sbjct: 81 LVQACYHKLDNKSHGGRTSQQERGQEG-----AQDCKFPG------NTGRQHRQRHEEER 129
Query: 528 QGSHHEQSVNRSGHSGSHHSHTTSQGRSDASHGQSGSRSA-SRQTRNEEQSGDGTRHSGS 586
Q SHH Q + G S HH Q R D+ HGQS + S ++ E Q D +
Sbjct: 130 QNSHHSQPERQDGDS--HHGQPERQDR-DSHHGQSEKQDRDSHHSQPERQDRDSHHNQSE 186
Query: 587 RHHEASSQADSSRHSQVGQGQSSGPRTSRNQGSSVSQDSDSQGHSEDSERWSGSASRNHH 646
R + S S R SQ SSG + S S S + QGH R +H+
Sbjct: 187 RQDKDFSFDQSERQSQ---DSSSGKKVSHK---STSGQAKWQGHIFALNRCEKPIQDSHY 240
Query: 647 GSAQEQSRDGSRHPRSHHEDRAGHGHSADSSRKSGTRHTQNSSSGQAASSHEQARSSAGE 706
G ++ ++ ++ H ++ + +KSG+ Q+ GQ + R
Sbjct: 241 GQSERHTQQSETLGQASHFNQT-------NQQKSGSYCGQSERLGQELGCGQTDRQGQSS 293
Query: 707 RHGSRHQLQSADSSRHSGTGHGQASSAVRDSGHRGSSGSQATDSEGHSEDSDTQSVSGHG 766
+G Q D S H G Q S+ H +D Q G
Sbjct: 294 HYG---QTDRQDQSYHYGQTDRQGQSS-------------------HYSQTDRQ-----G 326
Query: 767 QAGHHQQSHQESARDRSGERSRRSGSFLYQVSTHKQSESSHGWTGPSTGVRQG--SHHEQ 824
Q+ H+ Q ++ G+ R+ + Y T++Q + SH ++ P+ RQG SH+ Q
Sbjct: 327 QSSHYSQPDRQGQSSHYGQMDRKGQCYHYD-QTNRQGQGSH-YSQPN---RQGQSSHYGQ 381
Query: 825 --ARDNSRHSASQDGQDTIRGHPGSSRRGRQGSHHEQSVDRSGHSGSHHSHTTSQGRSD- 881
+D S H D QD H G + R Q SH+ Q +DR G GSH+ T QG+S
Sbjct: 382 PDTQDQSSHYGQTDRQDQ-SSHYGQTERQGQSSHYSQ-MDRQGQ-GSHYGQTDRQGQSSH 438
Query: 882 -ASRGQSGSRSA-SRTTRNEEQSRDGS--RHSGSRHH-------EASSHADISRHSQA-- 928
+ G S +T R + S G R S H+ ++S + I R Q+
Sbjct: 439 YGQPDRQGQNSHYGQTDRQGQSSHYGQTDRQGQSSHYSQPDKQGQSSHYGKIDRQDQSYH 498
Query: 929 -----GQGQSEGSRTSRRQGSSVSQDS-DSEGHSEDSERWSGSASRNHRGSAQEQSRHGS 982
GQGQS + RQG S D +G S + +H G Q +
Sbjct: 499 YGQPDGQGQSSHYGQTDRQGQSFHYGQPDRQGQSSHYSQMDRQGQSSHYGQTDRQGQS-- 556
Query: 983 RHPRSHH--EDRAGHG-HSADSSRQSGTPHAETSSGGQAASSHEQARSSPGERHGSRHQQ 1039
SH+ DR G H + RQ + H S G+ ++ + + G R S +Q
Sbjct: 557 ----SHYGQTDRQGQSYHYGQTDRQGQSSHYIQSQTGEIQGQNKYFQGTEGTRKASYVEQ 612
Query: 1040 SADSSRHSGIPRRQASSAVRDSGHWGSSGSQASDSEGHSEESDTQSVSGHGQDGPHQQSH 1099
S S R S Q + G + S SQ + + E D+Q H Q Q
Sbjct: 613 SGRSGRLSQQTPGQEGYQNQGQG-FQSRDSQQNGHQVWEPEEDSQ----HHQHKLLAQIQ 667
Query: 1100 QE-----SARDWSGGRSGRSGSFIYQVSTHEQSESAHGRTRTSTGRRQGSHHEQARDSSR 1154
QE RDW S Q Q+ +HG + + H R S
Sbjct: 668 QERPLCHKGRDWQSCSS-------EQGHRQAQTRQSHGEGLSHWAEEEQGHQTWDRHSHE 720
Query: 1155 HSASQEGQDTIRAH---PGSRRGGRQGSHHEQSVDRSGHSGSHHSHTTSQGRSDASHGQS 1211
G R H +R RQ HEQS R +H Q R
Sbjct: 721 SQEGPCGTQDRRTHKDEQNHQRRDRQTHEHEQSHQRR----DRQTHEDKQNR-------- 768
Query: 1212 GSRSASRQTRKDKQS 1226
+ RQT +D+Q+
Sbjct: 769 --QRRDRQTHEDEQN 781
Score = 146 bits (368), Expect = 5e-34
Identities = 184/755 (24%), Positives = 283/755 (37%), Gaps = 113/755 (14%)
Query: 2229 QSSGPRTSRP-RGSSVSQDSDSEGHSEDSERRSGSASRNHHGSAQEQSRDG-SRHPRSHH 2286
+S G RTS+ RG +QD G++ R+ R + +Q + +DG S H +
Sbjct: 92 KSHGGRTSQQERGQEGAQDCKFPGNTGRQHRQRHEEERQNSHHSQPERQDGDSHHGQPER 151
Query: 2287 EDRAGHGHSAESSRQSGTHHAENSSGGQAASSHEQARSSAGERHGSHHQQSADSSRHSGI 2346
+DR H H + +HH++ + + ++ R +QS DSS +
Sbjct: 152 QDRDSH-HGQSEKQDRDSHHSQPERQDRDSHHNQSERQDKDFSFDQSERQSQDSSSGKKV 210
Query: 2347 GHGQASSAVRDSGH--------RGSSGSQASDSEGHSEDSDTQSVSAHGQAGPHQQSHQE 2398
H S + GH + S SE H++ S+T GQA Q++Q+
Sbjct: 211 SHKSTSGQAKWQGHIFALNRCEKPIQDSHYGQSERHTQQSETL-----GQASHFNQTNQQ 265
Query: 2399 STRGRSAGRSGRSGSFLYQVSTHEQSESAH-GRTGTSTGG-RQGSHHKQARDSSRHSTSQ 2456
+ G G+S R G L T Q +S+H G+T G +Q + S T +
Sbjct: 266 KS-GSYCGQSERLGQELGCGQTDRQGQSSHYGQTDRQDQSYHYGQTDRQGQSSHYSQTDR 324
Query: 2457 EGQDTIHGHPGSSSGGRQGSHYEQLVDRSGHSGSHHSHTTSQGRSDASHGHSGSRSASRQ 2516
+GQ + + P Q SHY Q+ DR G H+ T QG+ SH +R
Sbjct: 325 QGQSSHYSQPDRQG---QSSHYGQM-DRKGQC-YHYDQTNRQGQ--GSHYSQPNRQGQSS 377
Query: 2517 TRNDEQSGDGSRHSGSRHHEASSRADSSGHSQVGQGQSEGPRTSRNWGSSFSQDSDSQGH 2576
+ D S H G + R D S H GQ+E R SS D QG
Sbjct: 378 HYGQPDTQDQSSHYGQ-----TDRQDQSSH----YGQTE-----RQGQSSHYSQMDRQGQ 423
Query: 2577 SEDSERWSGSASRNHHGSAQEQLRDGSRHPRSHQEDRAG-HGHSADSSRQSGTRH-TQTS 2634
+ +H+G Q DR G + H + RQ + H QT
Sbjct: 424 GSHYGQTDRQGQSSHYG----------------QPDRQGQNSHYGQTDRQGQSSHYGQTD 467
Query: 2635 SGGQAASSHEQARSSAGERHGSHHQQSADSSRHSGIGHGQASSAVRDSGHRGYSGSQASD 2694
GQ++ + + +G +Q D S H G GQ S+
Sbjct: 468 RQGQSSHYSQPDKQGQSSHYGKIDRQ--DQSYHYGQPDGQGQSS---------------- 509
Query: 2695 NEGHSEDSDTQSVSAH-GQAGSHQQSHQESARGRSGETSGHSGSFLYQVSTHEQSESSH- 2752
H +D Q S H GQ QS S R G++S H G T Q +SSH
Sbjct: 510 ---HYGQTDRQGQSFHYGQPDRQGQSSHYSQMDRQGQSS-HYG------QTDRQGQSSHY 559
Query: 2753 GWTGPSTRGRQGSRHEQAQDSSRHSASQDGQDTIRGHPGSSRGGRQGYHHEHSVDSSGHS 2812
G T + + ++ SS + SQ G+ I+G G +G V+ SG S
Sbjct: 560 GQTDRQGQSYHYGQTDRQGQSSHYIQSQTGE--IQGQ-NKYFQGTEGTRKASYVEQSGRS 616
Query: 2813 GSHHSHTTSQGRSDASRGQSGSRSASRTTRNEEQSGDGSR----HSGSRHHEASTHADIS 2868
G S + GQ G ++ + ++ + +G + S+HH+ A I
Sbjct: 617 GR---------LSQQTPGQEGYQNQGQGFQSRDSQQNGHQVWEPEEDSQHHQHKLLAQIQ 667
Query: 2869 RHSQAVQGQSEGSRRSRRQGSSVSQ--DSDSEGHSEDSERWSGSASRNHHGSAQEQLRDG 2926
+ + S QG +Q S EG S +E G + + H ++ G
Sbjct: 668 QERPLCHKGRDWQSCSSEQGHRQAQTRQSHGEGLSHWAEEEQGHQTWDRHSHESQEGPCG 727
Query: 2927 SRHPRSHQE-------DRAGHGHSADSSRQSGTRH 2954
++ R+H++ DR H H R+ H
Sbjct: 728 TQDRRTHKDEQNHQRRDRQTHEHEQSHQRRDRQTH 762
Score = 144 bits (363), Expect = 2e-33
Identities = 170/742 (22%), Positives = 269/742 (36%), Gaps = 82/742 (11%)
Query: 1256 QSSGSRTSRHQ-GSSVSQDSDSERHSDDSERLSGSASRNHHGSSREQSRDGSRHPGF-HQ 1313
+S G RTS+ + G +QD ++ R R + S+ + +DG H G +
Sbjct: 92 KSHGGRTSQQERGQEGAQDCKFPGNTGRQHRQRHEEERQNSHHSQPERQDGDSHHGQPER 151
Query: 1314 EDRASHGHSADSSRQSGTHHTESSSHGQAVSSHEQARSSPGERHGSRHQQSADSSRHSGI 1373
+DR SH H + +HH++ + ++ R +QS DSS +
Sbjct: 152 QDRDSH-HGQSEKQDRDSHHSQPERQDRDSHHNQSERQDKDFSFDQSERQSQDSSSGKKV 210
Query: 1374 GHRQASSAVRDSGH--------RGSSGSQVTNSEGHSEDSDTQSVSAHGQAGPHQQSHKE 1425
H+ S + GH + S SE H++ S+T GQA Q++++
Sbjct: 211 SHKSTSGQAKWQGHIFALNRCEKPIQDSHYGQSERHTQQSETL-----GQASHFNQTNQQ 265
Query: 1426 SARGQSGESSGRSRSFLYQVSSHEQSESTHGQT-APSTGGRQGSRHEQARNSSRHSASQD 1484
+ G+S + + + S +GQT G Q ++S +
Sbjct: 266 KSGSYCGQSERLGQELGCGQTDRQGQSSHYGQTDRQDQSYHYGQTDRQGQSSHYSQTDRQ 325
Query: 1485 GQDTIRGHPGSSRGGRQG-SYHEQSVDRSGHSGYHHSHTTPQGRSD--ASHGQSGPRSAS 1541
GQ + P RQG S H +DR G YH+ T QG+ + + G S
Sbjct: 326 GQSSHYSQP-----DRQGQSSHYGQMDRKGQC-YHYDQTNRQGQGSHYSQPNRQGQSSHY 379
Query: 1542 RQTRNEEQS---GDGSRHSGSRHHEPSTRAGSSRH----SQVGQGESAGSKTSRRQGSSV 1594
Q ++QS G R S H+ + R G S H + GQG G +T R+ SS
Sbjct: 380 GQPDTQDQSSHYGQTDRQDQSSHYGQTERQGQSSHYSQMDRQGQGSHYG-QTDRQGQSSH 438
Query: 1595 SQDRDSEGHSEDSERRSESASRNHYGSAREQSRHGSRNPRSHQEDRASHGHSAESSRQSG 1654
D +G + + +HYG + R G + S + + H + RQ
Sbjct: 439 YGQPDRQGQNSHYGQTDRQGQSSHYG---QTDRQGQSSHYSQPDKQGQSSHYGKIDRQDQ 495
Query: 1655 TRHAETSSGGQAASSQEQARSSPGERHGSRHQQSADSSTDSGTGRRQDSSVVGDSGNRGS 1714
+ H G +S Q H + + SS S R+ SS G + +G
Sbjct: 496 SYHYGQPDGQGQSSHYGQTDRQGQSFHYGQPDRQGQSSHYSQMDRQGQSSHYGQTDRQGQ 555
Query: 1715 SGSQASDSEGHSEESDTQSVSAHGQAGPHQQSHQESTRGQSGERSGRSGSFLYQVSTHEQ 1774
S H ++D Q S H Q + Q+GE G++ F
Sbjct: 556 S--------SHYGQTDRQGQSYHYGQTDRQGQSSHYIQSQTGEIQGQNKYF--------- 598
Query: 1775 SESAHGRTGPSTGGRQRSRHEQARDSSRHSASQEGQDTI--RGHPGSSRGGRQGSH--YE 1830
+ G R+ S EQ+ S R S GQ+ +G SR +Q H +E
Sbjct: 599 --------QGTEGTRKASYVEQSGRSGRLSQQTPGQEGYQNQGQGFQSRDSQQNGHQVWE 650
Query: 1831 QSVDSSGHSGSHHSH----TTSQERSDVSRGQS----GSRSVSRQTRNEKQSGDGSRHSG 1882
DS HH H QER +G+ S RQ + + G+G H
Sbjct: 651 PEEDS-----QHHQHKLLAQIQQERPLCHKGRDWQSCSSEQGHRQAQTRQSHGEGLSHWA 705
Query: 1883 SRHHEASSRADSSRHSQVGQGQSSGPRTSRNQGSSVSQDSDSQGHSEDSERWSGSASRNH 1942
+ S SQ G + RT +++ + +D + H + +R + H
Sbjct: 706 EEEQGHQTWDRHSHESQEGPCGTQDRRTHKDEQNHQRRDRQTHEHEQSHQR---RDRQTH 762
Query: 1943 LGSAWEQSRDGSRHPGSHHEDR 1964
Q RD H + R
Sbjct: 763 EDKQNRQRRDRQTHEDEQNHQR 784
Score = 142 bits (358), Expect = 7e-33
Identities = 175/748 (23%), Positives = 283/748 (37%), Gaps = 88/748 (11%)
Query: 2874 VQGQSEGSRRSRRQ-GSSVSQDSDSEGHSEDSERWSGSASRNHHGSAQEQLRDG-SRHPR 2931
+ +S G R S+++ G +QD G++ R R + +Q + +DG S H +
Sbjct: 89 LDNKSHGGRTSQQERGQEGAQDCKFPGNTGRQHRQRHEEERQNSHHSQPERQDGDSHHGQ 148
Query: 2932 SHQEDRAGHGHSADSSRQSGTRHTQTSSGGQAASSHEQARSSAGERHGSHHQQSADSSRH 2991
++DR H H + + H+Q + + ++ R +QS DSS
Sbjct: 149 PERQDRDSH-HGQSEKQDRDSHHSQPERQDRDSHHNQSERQDKDFSFDQSERQSQDSSSG 207
Query: 2992 SGIGHGQASSAVRDSGH--------RGYSGSQASDNEGHSEDSDTQSVSAHGQAGSHQQS 3043
+ H S + GH + S +E H++ S+T GQA Q+
Sbjct: 208 KKVSHKSTSGQAKWQGHIFALNRCEKPIQDSHYGQSERHTQQSETL-----GQASHFNQT 262
Query: 3044 HQESARGRSGETSGHSGSFLYQVSTHEQSESSH-GWTGPSTRG-------RQGSRHEQAQ 3095
+Q+ + G+ S G L T Q +SSH G T + RQG +Q
Sbjct: 263 NQQKSGSYCGQ-SERLGQELGCGQTDRQGQSSHYGQTDRQDQSYHYGQTDRQGQSSHYSQ 321
Query: 3096 DSSRHSASQYGQDTIRG---HPGSSRGGRQGYHHEHSVDSSGHSGSHHSHTTSQGRSDAS 3152
+ +S Y Q +G H G Q YH++ + + GSH+S QG+S +
Sbjct: 322 TDRQGQSSHYSQPDRQGQSSHYGQMDRKGQCYHYDQT--NRQGQGSHYSQPNRQGQS-SH 378
Query: 3153 RGQSGSRSASRTTRNEEQSGDSSRHSVSRHHEASTHADISRHSQAVQGQSEGSR--RSRR 3210
GQ ++ S G + R S H+ + S H + Q +GS ++ R
Sbjct: 379 YGQPDTQDQS------SHYGQTDRQDQSSHYGQTERQGQSSHYSQMDRQGQGSHYGQTDR 432
Query: 3211 QG-SSVSQDSDSEGHSEDSERWSGSASRNHRGSVQEQSRHGSRHPRSHHEDRAGHGHSAD 3269
QG SS D +G + + +H G Q + S + + + ++ H D
Sbjct: 433 QGQSSHYGQPDRQGQNSHYGQTDRQGQSSHYGQTDRQGQ-SSHYSQPDKQGQSSHYGKID 491
Query: 3270 RSRQSGTRHAETSSGGQAASSHEQARSSPGERHGSRHQQSADSSRHSGIPRGQASSAVRD 3329
R QS + GQ SSH +G +Q S H G P Q S+
Sbjct: 492 RQDQS---YHYGQPDGQGQSSH----------YGQTDRQG--QSFHYGQPDRQGQSS--- 533
Query: 3330 SRHWGSSGSQASDSEGHSEESDTQSVSGH-GQAGPHQQSHQESARDRSGGRSGRSGSFLY 3388
H+ Q S H ++D Q S H GQ QS+ D R G+S ++
Sbjct: 534 --HYSQMDRQGQSS--HYGQTDRQGQSSHYGQTDRQGQSYHYGQTD----RQGQSSHYIQ 585
Query: 3389 QVSTHEQSESAHGRTRTSTGRRQGSHHEQARDSSRHSASQEGQDTI--RGHPGSSRRGRQ 3446
+ Q ++ + + + G R+ S+ EQ+ S R S GQ+ +G SR +Q
Sbjct: 586 SQTGEIQGQNKY--FQGTEGTRKASYVEQSGRSGRLSQQTPGQEGYQNQGQGFQSRDSQQ 643
Query: 3447 GSHYEQSVDRSGHSGSHHSH----TTSQGRSDASRGQS----GSRSASRQTRNDEQSGDG 3498
H V HH H Q R +G+ S RQ + + G+G
Sbjct: 644 NGH---QVWEPEEDSQHHQHKLLAQIQQERPLCHKGRDWQSCSSEQGHRQAQTRQSHGEG 700
Query: 3499 SRHSWSHHHEASTQADSSRH-SQSGQGQSAGPRTSRNQGSSVSQDSDSQGHSEDSERWSG 3557
H W+ + D H SQ G + RT +++ + +D + H + +R
Sbjct: 701 LSH-WAEEEQGHQTWDRHSHESQEGPCGTQDRRTHKDEQNHQRRDRQTHEHEQSHQR--- 756
Query: 3558 SASRNHRGSAQEQSRDGSRHPTSHHEDR 3585
+ H Q RD H + R
Sbjct: 757 RDRQTHEDKQNRQRRDRQTHEDEQNHQR 784
Score = 140 bits (353), Expect = 3e-32
Identities = 202/778 (25%), Positives = 281/778 (36%), Gaps = 121/778 (15%)
Query: 3063 LYQVSTHEQSESSHGW-TGPSTRGRQGSRHEQAQDSSRHSASQYGQDTIRGHPGSSRGGR 3121
L Q H+ SHG T RG++G AQD ++ +T R H R
Sbjct: 81 LVQACYHKLDNKSHGGRTSQQERGQEG-----AQDC------KFPGNTGRQHRQRHEEER 129
Query: 3122 QGYHHEHSVDSSGHSGSHHSHTTSQGRSDASRGQSGSRSASRTTRNEEQSGDSSRHSVSR 3181
Q HH G S HH Q R D+ GQS E+Q DS R
Sbjct: 130 QNSHHSQPERQDGDS--HHGQPERQDR-DSHHGQS-----------EKQDRDSHHSQPER 175
Query: 3182 HHEASTHADISRHSQAVQ-GQSEGSRRSRRQGSSVSQDSDSEGHSEDSERWSGSASRNHR 3240
S H R + QSE + G VS S S +W G +R
Sbjct: 176 QDRDSHHNQSERQDKDFSFDQSERQSQDSSSGKKVSHKSTS-----GQAKWQGHIFALNR 230
Query: 3241 GSVQEQSRHGSRHPRSHHEDRAGHGHSADRSRQSGTRHAETSSGGQAASSHEQARSSPGE 3300
Q H +G S ++QS T GQA+ ++ + G
Sbjct: 231 CEKPIQDSH--------------YGQSERHTQQSETL-------GQASHFNQTNQQKSGS 269
Query: 3301 RHGSRHQQSADSSRHSGIPRGQASSAVRDSRHWGSSGSQASDSEGHSEESDTQSVSGH-G 3359
G + + +GQ+S H+G + Q D H ++D Q S H
Sbjct: 270 YCGQSERLGQELGCGQTDRQGQSS-------HYGQTDRQ--DQSYHYGQTDRQGQSSHYS 320
Query: 3360 QAGPHQQSHQESARDRSG-----GRSGRSGSFLYQVSTHEQSESAHGRTRTSTGRRQGSH 3414
Q QS S DR G G+ R G + T+ Q + +H G Q SH
Sbjct: 321 QTDRQGQSSHYSQPDRQGQSSHYGQMDRKGQCYHYDQTNRQGQGSHYSQPNRQG--QSSH 378
Query: 3415 HEQ--ARDSSRHSASQEGQDTIRGHPGSSRRGRQGSHYEQSVDRSGHSGSHHSHTTSQGR 3472
+ Q +D S H + QD H G + R Q SHY Q +DR G GSH+ T QG+
Sbjct: 379 YGQPDTQDQSSHYGQTDRQDQ-SSHYGQTERQGQSSHYSQ-MDRQGQ-GSHYGQTDRQGQ 435
Query: 3473 S-----------DASRGQSGSRSASRQTRNDEQSGDGSRHSW-------SHHHEASTQAD 3514
S ++ GQ+ + S ++ G S +S SH+ + Q
Sbjct: 436 SSHYGQPDRQGQNSHYGQTDRQGQSSHYGQTDRQGQSSHYSQPDKQGQSSHYGKIDRQDQ 495
Query: 3515 SSRHSQ-SGQGQSAGPRTSRNQGSSVSQDS-DSQGHSEDSERWSGSASRNHRGSAQEQSR 3572
S + Q GQGQS+ + QG S D QG S + +H G Q +
Sbjct: 496 SYHYGQPDGQGQSSHYGQTDRQGQSFHYGQPDRQGQSSHYSQMDRQGQSSHYGQTDRQGQ 555
Query: 3573 DGSRHPTSHHEDRAGHG-HSAESSRQSGTHHAENSSGGQAASSHEQARSSAGERHGSHHQ 3631
T DR G H ++ RQ + H S G+ ++ + + G R S+ +
Sbjct: 556 SSHYGQT----DRQGQSYHYGQTDRQGQSSHYIQSQTGEIQGQNKYFQGTEGTRKASYVE 611
Query: 3632 QSADSSRHSGIGHGQASSAVRDSGHRGSSGSQASDSEGHSEDSDTQSVSAHGQAGPHQQS 3691
QS S R S GQ + G + S+ S GH + + + S H Q Q
Sbjct: 612 QSGRSGRLSQQTPGQEGYQNQGQGFQ----SRDSQQNGH-QVWEPEEDSQHHQHKLLAQI 666
Query: 3692 HQESTRGRSAGRSGRSGSFLYQVSTHEQSESAHGRAGPSTGGRQGSRHEQARDS-SRHS- 3749
QE R GR H Q+++ R G + EQ + RHS
Sbjct: 667 QQE----RPLCHKGRDWQSCSSEQGHRQAQT---RQSHGEGLSHWAEEEQGHQTWDRHSH 719
Query: 3750 ASQEG----QD--TIRGHPGSRRGGRQGSYHEQSVDRSGHSGSHHSHTTSQGRSDASH 3801
SQEG QD T + +R RQ HEQS R +H Q R +H
Sbjct: 720 ESQEGPCGTQDRRTHKDEQNHQRRDRQTHEHEQSHQRRDRQ-THEDKQNRQRRDRQTH 776
Score = 134 bits (338), Expect = 1e-30
Identities = 168/723 (23%), Positives = 255/723 (35%), Gaps = 78/723 (10%)
Query: 3224 HSEDSERWSGSASRNHRGSVQEQS----RHGSRHPRSHHEDRAGHGHSADRSRQSGTRHA 3279
H D++ G S+ RG Q + R R HE+ + H + RQ G H
Sbjct: 87 HKLDNKSHGGRTSQQERGQEGAQDCKFPGNTGRQHRQRHEEERQNSHHSQPERQDGDSHH 146
Query: 3280 ETSSGGQAASSHEQARSSPGERHGSRHQQSADSSRHSGIPRGQASSAVRDSRHWGSSGSQ 3339
S H Q+ + H S+ ++ S H+ R Q D S S
Sbjct: 147 GQPERQDRDSHHGQSEKQDRDSHHSQPERQDRDSHHNQSER-QDKDFSFDQSERQSQDSS 205
Query: 3340 ASDSEGHSEESDTQSVSGHGQA-----GPHQQSHQESARDRSGGRSGRSGSFLYQVSTHE 3394
+ H S GH A P Q SH + +R +S G + T++
Sbjct: 206 SGKKVSHKSTSGQAKWQGHIFALNRCEKPIQDSHYGQS-ERHTQQSETLGQASHFNQTNQ 264
Query: 3395 QSESAHGRTRTSTGRRQGSHHEQARDSSRHSASQEGQDTIRGHPGSSRRGRQGSHYEQSV 3454
Q ++ G+ G + S H + QD H G + R Q SHY Q+
Sbjct: 265 QKSGSYCGQSERLGQELGCGQTDRQGQSSHYGQTDRQDQSY-HYGQTDRQGQSSHYSQT- 322
Query: 3455 DRSGHSGSHHSHTTSQGRSDASRGQSGSRSASRQTRNDEQSGDGSRHSW-------SHHH 3507
DR G S SH+S QG+S + GQ + + G GS +S SH+
Sbjct: 323 DRQGQS-SHYSQPDRQGQS-SHYGQMDRKGQCYHYDQTNRQGQGSHYSQPNRQGQSSHYG 380
Query: 3508 EASTQADSSRHSQSGQGQSAGPRTSRNQGSSVSQDSDSQGHSEDSERWSGSASRNHRGSA 3567
+ TQ SS + Q T R SS ++ QG S + +H G
Sbjct: 381 QPDTQDQSSHYGQ----------TDRQDQSSHYGQTERQGQSSHYSQMDRQGQGSHYGQT 430
Query: 3568 QEQSRDGSRHPTSHH--EDRAG-HGHSAESSRQS-GTHHAENSSGGQAASSHEQARSSAG 3623
Q + +SH+ DR G + H ++ RQ +H+ + GQ++ + +
Sbjct: 431 DRQGQ------SSHYGQPDRQGQNSHYGQTDRQGQSSHYGQTDRQGQSSHYSQPDKQGQS 484
Query: 3624 ERHGSHHQQSADSSRHSGIGHGQASSAVRDSGHRGSSGSQASDSEGHSEDSDTQSVSAHG 3683
+G +Q D S H G GQ S+ H G + Q D QS
Sbjct: 485 SHYGKIDRQ--DQSYHYGQPDGQGQSS-----HYGQTDRQGQSFHYGQPDRQGQSSHYSQ 537
Query: 3684 QAGPHQQSH--QESTRGRSA--GRSGRSGSFLYQVSTHEQSESAH---GRAGPSTG---- 3732
Q SH Q +G+S+ G++ R G + T Q +S+H + G G
Sbjct: 538 MDRQGQSSHYGQTDRQGQSSHYGQTDRQGQSYHYGQTDRQGQSSHYIQSQTGEIQGQNKY 597
Query: 3733 --GRQGSRH----EQARDSSRHSASQEGQDTIRGHPGSRRGGRQGSYHEQSVDRSGHSGS 3786
G +G+R EQ+ S R S GQ+ + G R + V
Sbjct: 598 FQGTEGTRKASYVEQSGRSGRLSQQTPGQEGYQNQ-GQGFQSRDSQQNGHQVWEPEEDSQ 656
Query: 3787 HHSHTT----SQGRSDASHGQS----GSRSASRETRNEEQSGDGSRHSGSRHHEASTQAD 3838
HH H Q R G+ S R+ + + G+G H T
Sbjct: 657 HHQHKLLAQIQQERPLCHKGRDWQSCSSEQGHRQAQTRQSHGEGLSHWAEEEQGHQTWDR 716
Query: 3839 SSRHSQSGQGESAGSRRSRRQGSSVSQDSDSEAYPEDSERRSESASRNHHGSSREQSRDG 3898
S SQ G + R + + + +D + + + +RR + H Q RD
Sbjct: 717 HSHESQEGPCGTQDRRTHKDEQNHQRRDRQTHEHEQSHQRRDR---QTHEDKQNRQRRDR 773
Query: 3899 SRH 3901
H
Sbjct: 774 QTH 776
Score = 131 bits (329), Expect = 2e-29
Identities = 178/757 (23%), Positives = 286/757 (37%), Gaps = 97/757 (12%)
Query: 3182 HHEASTHADISRHSQAVQGQSEGSRRSRRQGSSVSQ------DSDSEGHSEDSERWSGSA 3235
+H+ + R SQ +GQ EG++ + G++ Q + H ER G +
Sbjct: 86 YHKLDNKSHGGRTSQQERGQ-EGAQDCKFPGNTGRQHRQRHEEERQNSHHSQPERQDGDS 144
Query: 3236 SRNHRGSVQEQSRHGSRHPRSHHEDRAGHGHSADRSRQSGTRHAETSSGGQAASSHEQAR 3295
H G + Q R S H +S +DR H HS + + H ++ + S + R
Sbjct: 145 ---HHGQPERQDRD-SHHGQSEKQDRDSH-HSQPERQDRDSHHNQSERQDKDFSFDQSER 199
Query: 3296 SSPGERHGSR--HQQSADSSRHSG--IPRGQASSAVRDSRHWGSSGSQASDSEGHSEESD 3351
S G + H+ ++ ++ G + ++DS H+G S E H+++S+
Sbjct: 200 QSQDSSSGKKVSHKSTSGQAKWQGHIFALNRCEKPIQDS-HYGQS-------ERHTQQSE 251
Query: 3352 TQSVSGHGQAGPHQQSHQESARDRSGGRSGRSGSFLYQVSTHEQSESAH-GRT-RTSTGR 3409
T GQA Q++Q+ + G +S R G L T Q +S+H G+T R
Sbjct: 252 TL-----GQASHFNQTNQQKSGSYCG-QSERLGQELGCGQTDRQGQSSHYGQTDRQDQSY 305
Query: 3410 RQGSHHEQARDSSRHSASQEGQDTIRGHPGSSRRGRQGSHYEQSVDRSGH---------- 3459
G Q + S ++GQ + P R+G Q SHY Q +DR G
Sbjct: 306 HYGQTDRQGQSSHYSQTDRQGQSSHYSQP--DRQG-QSSHYGQ-MDRKGQCYHYDQTNRQ 361
Query: 3460 -SGSHHSHTTSQGRSDASRGQSGSRSASR---QTRNDEQSGDGSRHSWSHHHEASTQADS 3515
GSH+S QG+S + GQ ++ S QT +QS SH+ + Q S
Sbjct: 362 GQGSHYSQPNRQGQS-SHYGQPDTQDQSSHYGQTDRQDQS--------SHYGQTERQGQS 412
Query: 3516 SRHSQ---SGQGQSAGPRTSRNQGSSVSQDSDSQGHSEDSERWSGSASRNHRGSAQEQSR 3572
S +SQ GQG G + Q S Q D QG + + +H G + R
Sbjct: 413 SHYSQMDRQGQGSHYGQTDRQGQSSHYGQP-DRQGQNSHYGQTDRQGQSSHYG---QTDR 468
Query: 3573 DGSRHPTSHHEDRAGHGHSAESSRQSGTHHAENSSGGQAASSHEQARSSAGERHGSHHQQ 3632
G S + + H + RQ ++H G +S + Q H +
Sbjct: 469 QGQSSHYSQPDKQGQSSHYGKIDRQDQSYHYGQPDGQGQSSHYGQTDRQGQSFHYGQPDR 528
Query: 3633 SADSSRHSGIGHGQASSAVRDSGHRGSSGSQASDSEGHSEDSDTQSVSAH-------GQA 3685
SS +S + SS H G + Q S H +D Q S H GQ+
Sbjct: 529 QGQSSHYSQMDRQGQSS------HYGQTDRQGQSS--HYGQTDRQGQSYHYGQTDRQGQS 580
Query: 3686 GPHQQSHQESTRGRSAGRSGRSGSFLYQVSTHEQSESAHGRAGPSTGGRQGSRHEQARDS 3745
+ QS +G++ G G+ + +++ + GR T G++G +++
Sbjct: 581 SHYIQSQTGEIQGQNKYFQGTEGT---RKASYVEQSGRSGRLSQQTPGQEGYQNQGQGFQ 637
Query: 3746 SRHSASQEGQDTIRGHPGSRRGGRQGSYHEQSVDRSGHSGSH-HSHTTSQGRSDASHGQS 3804
SR S Q G S+ + Q H G S ++ QG A QS
Sbjct: 638 SRDS-QQNGHQVWEPEEDSQHHQHKLLAQIQQERPLCHKGRDWQSCSSEQGHRQAQTRQS 696
Query: 3805 GSRSASRETRNEEQSGDGSRHSGSRHHEASTQADSSRHSQSGQGESAGSRRSRRQGSSVS 3864
S E+ RHS HE+ ++ ++ + E RR R
Sbjct: 697 HGEGLSHWAEEEQGHQTWDRHS----HESQEGPCGTQDRRTHKDEQNHQRRDR------- 745
Query: 3865 QDSDSEAYPEDSERRSESASRNHHGSSREQSRDGSRH 3901
Q + E + +R++ +N R+ D H
Sbjct: 746 QTHEHEQSHQRRDRQTHEDKQNRQRRDRQTHEDEQNH 782
Score = 131 bits (329), Expect = 2e-29
Identities = 161/732 (21%), Positives = 273/732 (37%), Gaps = 61/732 (8%)
Query: 932 QSEGSRTSRRQ-GSSVSQDSDSEGHSEDSERWSGSASRNHRGSAQEQSRHG-SRHPRSHH 989
+S G RTS+++ G +QD G++ R R + +Q + + G S H +
Sbjct: 92 KSHGGRTSQQERGQEGAQDCKFPGNTGRQHRQRHEEERQNSHHSQPERQDGDSHHGQPER 151
Query: 990 EDRAGHGHSADSSRQSGTPHAETSSGGQAASSHEQARSSPGERHGSRHQQSADSSRHSGI 1049
+DR H H + + H++ + + ++ R +QS DSS +
Sbjct: 152 QDRDSH-HGQSEKQDRDSHHSQPERQDRDSHHNQSERQDKDFSFDQSERQSQDSSSGKKV 210
Query: 1050 PRRQASSAVRDSGHWGS--------SGSQASDSEGHSEESDTQSVSGHGQDGPHQQSHQE 1101
+ S + GH + S SE H+++S+T GQ Q++Q+
Sbjct: 211 SHKSTSGQAKWQGHIFALNRCEKPIQDSHYGQSERHTQQSETL-----GQASHFNQTNQQ 265
Query: 1102 SARDWSGGRSGRSGSFIYQVSTHEQSESAH-GRT-RTSTGRRQGSHHEQARDSSRHSASQ 1159
+ + G+S R G + T Q +S+H G+T R G Q + S +
Sbjct: 266 KSGSYC-GQSERLGQELGCGQTDRQGQSSHYGQTDRQDQSYHYGQTDRQGQSSHYSQTDR 324
Query: 1160 EGQDTIRAHPGSRRGGRQGSHHEQSVDRSGHSGSHHSHTTSQGRSDASHGQSGSRSASRQ 1219
+GQ + + P R+G Q SH+ Q +DR G H+ T QG+ SH +R
Sbjct: 325 QGQSSHYSQP-DRQG--QSSHYGQ-MDRKGQC-YHYDQTNRQGQ--GSHYSQPNRQGQSS 377
Query: 1220 TRKDKQSGDGSRHSGSRHHEAASWADSSRHSQVGQEQSSGSRTSRHQGSSVSQDSDSERH 1279
+ D S H G + D S H GQ + G + Q Q S H
Sbjct: 378 HYGQPDTQDQSSHYGQTDRQ-----DQSSH--YGQTERQGQSSHYSQMDRQGQGS----H 426
Query: 1280 SDDSERLSGSASRNHHGSSREQSRDGSRHPGFHQEDRASHGHSADSSRQSGTHHTESSSH 1339
++R S +H+G Q ++ S + ++ ++SH D QS +H+++
Sbjct: 427 YGQTDRQGQS---SHYGQPDRQGQN-SHYGQTDRQGQSSHYGQTDRQGQS-SHYSQPDKQ 481
Query: 1340 GQAVSSHEQARSSPGERHGSRHQQSADSSRHSGIGHRQASSAVRDSGHRGSSGSQVTNSE 1399
GQ+ + R +G Q S H G RQ S R S + +
Sbjct: 482 GQSSHYGKIDRQDQSYHYGQPDGQG--QSSHYGQTDRQGQSFHYGQPDRQGQSSHYSQMD 539
Query: 1400 GHSEDSDTQSVSAHGQAGPHQQSHKESARGQSGESSGRSRSFLYQVSSHEQSESTHGQTA 1459
+ S GQ+ + Q+ ++ G++ + +S Y S + + +
Sbjct: 540 RQGQSSHYGQTDRQGQSSHYGQTDRQGQSYHYGQTDRQGQSSHYIQSQTGEIQGQNKYFQ 599
Query: 1460 PSTGGRQGSRHEQARNSSRHSASQDGQDTIRGHPGSSRGGRQGSYHEQSVDRSGHSGYHH 1519
+ G R+ S EQ+ S R S GQ+ + + G R + V HH
Sbjct: 600 GTEGTRKASYVEQSGRSGRLSQQTPGQEGYQ-NQGQGFQSRDSQQNGHQVWEPEEDSQHH 658
Query: 1520 SH----TTPQGRSDASHGQSGPRSAS----RQTRNEEQSGDGSRHSGSRHHEPSTRAGSS 1571
H Q R G+ +S RQ + + G+G H T S
Sbjct: 659 QHKLLAQIQQERPLCHKGRDWQSCSSEQGHRQAQTRQSHGEGLSHWAEEEQGHQTWDRHS 718
Query: 1572 RHSQVGQGESAGSKTSRRQGSSVSQDRDSEGHSEDSERRSESASRNHYGSAREQSRHGSR 1631
SQ G + +T + + + +DR + H + +RR E ++ R
Sbjct: 719 HESQEGPCGTQDRRTHKDEQNHQRRDRQTHEHEQSHQRRDR--------QTHEDKQNRQR 770
Query: 1632 NPRSHQEDRASH 1643
R ED +H
Sbjct: 771 RDRQTHEDEQNH 782
Score = 129 bits (323), Expect = 8e-29
Identities = 184/776 (23%), Positives = 275/776 (35%), Gaps = 137/776 (17%)
Query: 1814 RGHPGSSRGGRQGSHYEQSVDSSGHSGSHHSHTTSQERSDVSRGQSGSRSVSRQTRNEKQ 1873
+ H G + +G Q G++G H +ER + S ++ E+Q
Sbjct: 92 KSHGGRTSQQERGQEGAQDCKFPGNTGRQHRQRHEEERQN-----------SHHSQPERQ 140
Query: 1874 SGDGSRHSGSRHHEASSRADSSRHSQVGQGQSSGPRTSRNQGSSVSQDSDSQGHSEDSER 1933
GD HH R D H GQS + QD DS H SER
Sbjct: 141 DGDS-------HHGQPERQDRDSH----HGQSEKQDRDSHHSQPERQDRDS--HHNQSER 187
Query: 1934 WSGSASRNHLGSAWEQSRDGSRHPGSHHEDRAGH----GHS----------ADSSRQSGT 1979
S + QS+D S H+ +G GH DS
Sbjct: 188 QDKDFS---FDQSERQSQDSSSGKKVSHKSTSGQAKWQGHIFALNRCEKPIQDSHYGQSE 244
Query: 1980 RHTESSSR-GQAA----SSHEQARSSAGERHGSHHQLQSADSSRHSGIGHGQASSAVRDS 2034
RHT+ S GQA+ ++ +++ S G+ +L + R H + S
Sbjct: 245 RHTQQSETLGQASHFNQTNQQKSGSYCGQSERLGQELGCGQTDRQGQSSHYGQTDRQDQS 304
Query: 2035 GHRGYSGSQASDSEGHSEDSDTQSVSAQGKAGPHQQSHKESARGQSGESSGRSGSFLYQV 2094
H G + Q S H +D QG++ + Q ++ G+ R G +
Sbjct: 305 YHYGQTDRQGQSS--HYSQTD-----RQGQSSHYSQPDRQGQSSHYGQMD-RKGQCYHYD 356
Query: 2095 STHEQSESTHGQSAPSTGGRQGSHYDQ--AQDSSRHSASQEGQDTIRGHPGPSRGGRQGS 2152
T+ Q + +H S P+ G Q SHY Q QD S H + QD H G + Q S
Sbjct: 357 QTNRQGQGSH-YSQPNRQG-QSSHYGQPDTQDQSSHYGQTDRQDQ-SSHYGQTERQGQSS 413
Query: 2153 HQEQSVDRSGHSGSHHSHTTSQGRS-----------DASRGQSGSRSASRKTYDKEQSGD 2201
H Q +DR G GSH+ T QG+S ++ GQ+ + S ++ G
Sbjct: 414 HYSQ-MDRQG-QGSHYGQTDRQGQSSHYGQPDRQGQNSHYGQTDRQGQSSHYGQTDRQGQ 471
Query: 2202 GSRHS------GSHHHEASSWADSSRH--SLVGQGQSSG-PRTSRPRGSSVSQDSDSEGH 2252
S +S S H+ D S H GQGQSS +T R S D +G
Sbjct: 472 SSHYSQPDKQGQSSHYGKIDRQDQSYHYGQPDGQGQSSHYGQTDRQGQSFHYGQPDRQGQ 531
Query: 2253 SEDSERRSGSASRNHHGSAQEQSRDGSRHPRSHH--EDRAGHG-HSAESSRQSGTHHAEN 2309
S + +H+G Q + SH+ DR G H ++ RQ + H
Sbjct: 532 SSHYSQMDRQGQSSHYGQTDRQGQS------SHYGQTDRQGQSYHYGQTDRQGQSSHYIQ 585
Query: 2310 SSGGQAASSHEQARSSAGERHGSHHQQSADSSRHSGIGHGQASSAVRDSGHRGSSGSQAS 2369
S G+ ++ + + G R S+ +QS S R S + + G +
Sbjct: 586 SQTGEIQGQNKYFQGTEGTRKASYVEQSGRSGRLS----------------QQTPGQEGY 629
Query: 2370 DSEGHSEDSDTQSVSAHGQAGPHQQSHQESTRGRSAGRSGRSGSFLYQVSTHEQSESAHG 2429
++G S + H P + S + L Q+ E+ G
Sbjct: 630 QNQGQGFQSRDSQQNGHQVWEPEEDSQHHQHK------------LLAQIQ-QERPLCHKG 676
Query: 2430 RTGTSTGGRQGSHHKQARDS-----SRHSTSQEGQDTIHGHPGSSSGGRQGSHYEQLVDR 2484
R S QG Q R S S + ++G T H S G G+ DR
Sbjct: 677 RDWQSCSSEQGHRQAQTRQSHGEGLSHWAEEEQGHQTWDRHSHESQEGPCGTQ-----DR 731
Query: 2485 SGHSGSHHSHTTSQGRSDASHGHSGS-RSASRQTRNDEQS---GDGSRHSGSRHHE 2536
+H Q R +H H S + RQT D+Q+ D H ++H+
Sbjct: 732 R----THKDEQNHQRRDRQTHEHEQSHQRRDRQTHEDKQNRQRRDRQTHEDEQNHQ 783
Score = 128 bits (322), Expect = 1e-28
Identities = 188/778 (24%), Positives = 283/778 (36%), Gaps = 118/778 (15%)
Query: 1927 HSEDSERWSGSASRNHLGSAWEQS-----RDGSRHPGSHHEDRAGHGHSADSSRQSGTRH 1981
H D++ G S+ G Q G +H H E+R HS RQ G H
Sbjct: 87 HKLDNKSHGGRTSQQERGQEGAQDCKFPGNTGRQHRQRHEEERQNSHHS-QPERQDGDSH 145
Query: 1982 TESSSRGQAASSHEQARSSAGERHGSHHQLQSADSSRHSGIGHGQASSAVRDSGHRGYSG 2041
R S H Q+ + H S + Q DS H Q+ +D S
Sbjct: 146 HGQPERQDRDSHHGQSEKQDRDSHHSQPERQDRDSH------HNQSERQDKDFSF-DQSE 198
Query: 2042 SQASDSEGHSEDSDTQSVSAQGK-----------AGPHQQSH--KESARGQSGESSGRSG 2088
Q+ DS + S +S S Q K P Q SH + Q E+ G++
Sbjct: 199 RQSQDSSSGKKVSH-KSTSGQAKWQGHIFALNRCEKPIQDSHYGQSERHTQQSETLGQAS 257
Query: 2089 SFLYQVSTHEQSESTHGQSAPSTGGRQGSHYDQAQDSSRHSASQEGQDTIRGHPGPSRGG 2148
F T++Q ++ + G G Q S H + QD + R G
Sbjct: 258 HF---NQTNQQKSGSYCGQSERLGQELGCGQTDRQGQSSHYGQTDRQDQSYHYGQTDRQG 314
Query: 2149 RQGSHQEQSVDRSGHSGSHHSHTTSQGRSDASRGQSGSRSASRKTYDKEQSGDGSRHSGS 2208
Q SH Q+ DR G S SH+S QG+S G + Y +Q+ + GS
Sbjct: 315 -QSSHYSQT-DRQGQS-SHYSQPDRQGQS----SHYGQMDRKGQCYHYDQT--NRQGQGS 365
Query: 2209 HHHEASSWADSSRHSLVG-QGQSSG-PRTSRPRGSSVSQDSDSEGHSEDSERRSGSASRN 2266
H+ + + SS + Q QSS +T R SS ++ +G S + +
Sbjct: 366 HYSQPNRQGQSSHYGQPDTQDQSSHYGQTDRQDQSSHYGQTERQGQSSHYSQMDRQGQGS 425
Query: 2267 HHGSAQEQSRDGSRHPRSHH--EDRAG-HGHSAESSRQ-SGTHHAENSSGGQAASSHEQA 2322
H+G Q + SH+ DR G + H ++ RQ +H+ + GQ++ +
Sbjct: 426 HYGQTDRQGQS------SHYGQPDRQGQNSHYGQTDRQGQSSHYGQTDRQGQSSHYSQPD 479
Query: 2323 RSSAGERHGSHHQQSADSSRHSGIGHGQASSAVRDSGHRGSSGSQASDSEGHSEDSDTQS 2382
+ +G +Q D S H G GQ S+ H G + Q H D Q
Sbjct: 480 KQGQSSHYGKIDRQ--DQSYHYGQPDGQGQSS-----HYGQTDRQGQSF--HYGQPDRQG 530
Query: 2383 VSAHGQAGPHQQSHQESTRGRSA--GRSGRSGSFLYQVSTHEQSESAH-GRTGTSTGGRQ 2439
S+H Q +G+S+ G++ R G + T Q +S H G+T RQ
Sbjct: 531 QSSH--------YSQMDRQGQSSHYGQTDRQGQSSHYGQTDRQGQSYHYGQT-----DRQ 577
Query: 2440 GSHHKQARDSSRHSTSQEGQDTIHGHPGSSSGGRQGSHYEQLVDRSGHSGSHHSHTTSQ- 2498
G SS + SQ G+ I G G +G+ V++SG SG T Q
Sbjct: 578 G-------QSSHYIQSQTGE--IQGQ-NKYFQGTEGTRKASYVEQSGRSGRLSQQTPGQE 627
Query: 2499 GRSDASHGHSGSRSASRQTRNDEQSGD--GSRHSGSRHHEASSRADSSGHSQVGQGQSEG 2556
G + G Q+R+ +Q+G S+HH+ H + Q Q E
Sbjct: 628 GYQNQGQGF--------QSRDSQQNGHQVWEPEEDSQHHQ---------HKLLAQIQQER 670
Query: 2557 P--RTSRNWGSSFSQDSDSQGHSEDSERWSGSASRNHHGSAQEQLRDGSRHPRSHQE--- 2611
P R+W S S QGH + R S +H ++ + RH QE
Sbjct: 671 PLCHKGRDWQSC----SSEQGHRQAQTRQSHGEGLSHWAEEEQGHQTWDRHSHESQEGPC 726
Query: 2612 ---DRAGHGHSADSSRQSGTRHTQTSSGGQAASSHEQARSSAGERHGSHHQQSADSSR 2666
DR H + R+ H S + + + + R H+ + R
Sbjct: 727 GTQDRRTHKDEQNHQRRDRQTHEHEQSHQRRDRQTHEDKQNRQRRDRQTHEDEQNHQR 784
Score = 128 bits (321), Expect = 1e-28
Identities = 186/772 (24%), Positives = 286/772 (37%), Gaps = 102/772 (13%)
Query: 988 HHEDRAGHGHSADSSRQSGTPHAETSSGGQAASSHEQARSSPGERHGSRHQQSA--DSSR 1045
H D HG + + G H Q ER S H Q D
Sbjct: 87 HKLDNKSHGGRTSQQERGQEGAQDCKFPGNTGRQHRQRHEE--ERQNSHHSQPERQDGDS 144
Query: 1046 HSGIPRRQASSAVRDSGHWGSSGSQASDSEGHSEESDTQSVSGHGQDGPHQQSHQESARD 1105
H G P RQ RDS H S+ D + H + + Q +D H QS ++ +D
Sbjct: 145 HHGQPERQD----RDSHH---GQSEKQDRDSHHSQPERQD-----RDSHHNQSERQD-KD 191
Query: 1106 WSGGRSGRSGSFIYQVSTHEQSESAHGRTRTSTGRRQGSHHEQARDSSRHSASQEGQDTI 1165
+S +S R QS+ + + S G Q + + + QD
Sbjct: 192 FSFDQSER------------QSQDSSSGKKVSHKSTSGQAKWQGHIFALNRCEKPIQD-- 237
Query: 1166 RAHPGSRRGGRQGSHHEQSVDRSGHSGSHHSHTTSQGRSDASHGQS---GSRSASRQTRK 1222
+H G Q H Q + G + H + T+Q +S + GQS G QT +
Sbjct: 238 -SHYG------QSERHTQQSETLGQAS--HFNQTNQQKSGSYCGQSERLGQELGCGQTDR 288
Query: 1223 DKQS---GDGSRHSGSRHH-EAASWADSSRHSQVG-QEQSSGSRTSRHQGSSV---SQDS 1274
QS G R S H+ + SS +SQ Q QSS QG S D
Sbjct: 289 QGQSSHYGQTDRQDQSYHYGQTDRQGQSSHYSQTDRQGQSSHYSQPDRQGQSSHYGQMDR 348
Query: 1275 DSERHSDDSERLSGSASRNHHGSSREQSRDGSRHPGFHQEDRASHGHSADSSRQSGTHHT 1334
+ + D G S H S + S + +D++SH D QS +H+
Sbjct: 349 KGQCYHYDQTNRQGQGS---HYSQPNRQGQSSHYGQPDTQDQSSHYGQTDRQDQS-SHYG 404
Query: 1335 ESSSHGQAVSSHEQARSSPGERHGSRHQQSADSSRHSGIGHRQASSAVRDSGHRGSSGSQ 1394
++ GQ+ + R G +G +Q S H G RQ ++ H G + Q
Sbjct: 405 QTERQGQSSHYSQMDRQGQGSHYGQTDRQG--QSSHYGQPDRQGQNS-----HYGQTDRQ 457
Query: 1395 VTNSEGHSEDSDTQSVSAHGQAGPHQQSHKESARGQSGESSGRSRSFLYQVSSHEQSEST 1454
+S H +D Q S+H + Q K+ G+ + +S+ Y + S
Sbjct: 458 GQSS--HYGQTDRQGQSSH-----YSQPDKQGQSSHYGKIDRQDQSYHYGQPDGQGQSSH 510
Query: 1455 HGQT-APSTGGRQGSRHEQARNSSRHSASQDGQDTIRGHPGSSRGGRQGSYHEQSVDRSG 1513
+GQT G Q ++S + GQ + H G + Q S++ Q+ DR G
Sbjct: 511 YGQTDRQGQSFHYGQPDRQGQSSHYSQMDRQGQSS---HYGQTDRQGQSSHYGQT-DRQG 566
Query: 1514 HSGYHHSHTTPQGRSDASHGQSGPRSASRQTRNEEQSGDGSRHSGSRHHEPSTRAGSSRH 1573
S YH+ T QG+S SH + Q +G+R + + E S R+G
Sbjct: 567 QS-YHYGQTDRQGQS--SHYIQSQTGEIQGQNKYFQGTEGTRKAS--YVEQSGRSGRLSQ 621
Query: 1574 SQVG------QGESAGSKTSRRQGSSV-SQDRDSEGHSE------DSERRSESASRNHYG 1620
G QG+ S+ S++ G V + DS+ H ER R+
Sbjct: 622 QTPGQEGYQNQGQGFQSRDSQQNGHQVWEPEEDSQHHQHKLLAQIQQERPLCHKGRDWQS 681
Query: 1621 SAREQSRHGSRNPRSHQEDRASHGHSAESSRQSGTRHAETSSGGQAASSQEQARSSPGER 1680
+ EQ ++ +SH E SH E Q+ RH+ S G +Q++ +
Sbjct: 682 CSSEQGHRQAQTRQSHGEG-LSHWAEEEQGHQTWDRHSHESQEG-PCGTQDRRTHKDEQN 739
Query: 1681 HGSRHQQSADSSTDSGTGRRQDSSVVGDSGNRGSSGSQASDSEGHSEESDTQ 1732
H R +Q+ + + +R+D D NR Q D + H +E + Q
Sbjct: 740 HQRRDRQTHEHEQ---SHQRRDRQTHEDKQNR-----QRRDRQTHEDEQNHQ 783
Score = 127 bits (319), Expect = 2e-28
Identities = 172/762 (22%), Positives = 271/762 (35%), Gaps = 114/762 (14%)
Query: 2415 LYQVSTHEQSESAHG-RTGTSTGGRQGSHHKQARDSSRHSTSQEGQDTIHGHPGSSSGGR 2473
L Q H+ +HG RT G++G+ + ++ Q ++ R
Sbjct: 81 LVQACYHKLDNKSHGGRTSQQERGQEGAQDCKFPGNTGRQHRQRHEEE-----------R 129
Query: 2474 QGSHYEQLVDRSGHSGSHHSHTTSQGRSDASHGHSGSRSASRQTRNDEQSGDGSRHSGSR 2533
Q SH+ Q + G SHH Q R D+ HG S + E+ S H+ S
Sbjct: 130 QNSHHSQPERQDG--DSHHGQPERQDR-DSHHGQSEKQDRDSHHSQPERQDRDSHHNQSE 186
Query: 2534 HHEASSRADSSGHSQVGQGQSEGPRTSRNWGSSFSQDSDSQGHSEDSERWSGSASRNHHG 2593
+ D S + Q S G + S S S + QGH R +H+G
Sbjct: 187 RQDKDFSFDQS--ERQSQDSSSGKKVSH---KSTSGQAKWQGHIFALNRCEKPIQDSHYG 241
Query: 2594 SAQEQLRDGSRHPRSHQEDRAGHGHSADSSRQSGTRHTQTSSGGQAASSHEQARSSAGER 2653
++ RH + + + + ++SG+ Q+ GQ + R
Sbjct: 242 QSE-------RHTQQSETLGQASHFNQTNQQKSGSYCGQSERLGQELGCGQTDRQGQSSH 294
Query: 2654 HGSHHQQSADSSRHSGIGHGQASSAVRDSGHRGYSGSQASDNEGHSEDSDTQSVSAH-GQ 2712
+G +Q D S H G Q S+ YS + H D Q S+H GQ
Sbjct: 295 YGQTDRQ--DQSYHYGQTDRQGQSS-------HYSQTDRQGQSSHYSQPDRQGQSSHYGQ 345
Query: 2713 AGSHQQSHQESARGRSGETSGHSGSFLYQVSTHEQSESSHGWTGPSTRGRQGSRHEQAQD 2772
Q + R G+ S +S + Q +SSH + P T QD
Sbjct: 346 MDRKGQCYHYDQTNRQGQGSHYS-------QPNRQGQSSH-YGQPDT-----------QD 386
Query: 2773 SSRHSASQDGQDTIRGHPGSSRGGRQGYHHEHSVDSSGHSGSHHSHTTSQGRS------- 2825
S H D QD + + R G+ H +D G GSH+ T QG+S
Sbjct: 387 QSSHYGQTDRQDQSSHYGQTERQGQSS--HYSQMDRQG-QGSHYGQTDRQGQSSHYGQPD 443
Query: 2826 ----DASRGQSGSRSASRTTRNEEQSGDGSRHS-GSRHHEASTHADISRHSQAV------ 2874
++ GQ+ + S ++ G S +S + ++S + I R Q+
Sbjct: 444 RQGQNSHYGQTDRQGQSSHYGQTDRQGQSSHYSQPDKQGQSSHYGKIDRQDQSYHYGQPD 503
Query: 2875 -QGQSEGSRRSRRQGSSVSQ-DSDSEGHSEDSERWSGSASRNHHGSAQEQLRDGSRHPRS 2932
QGQS ++ RQG S D +G S + +H+G Q +
Sbjct: 504 GQGQSSHYGQTDRQGQSFHYGQPDRQGQSSHYSQMDRQGQSSHYGQTDRQ----GQSSHY 559
Query: 2933 HQEDRAGHG-HSADSSRQSGTRHTQTSSGGQAASSHEQARSSAGERHGSHHQQSADSSR- 2990
Q DR G H + RQ + H S G+ ++ + + G R S+ +QS S R
Sbjct: 560 GQTDRQGQSYHYGQTDRQGQSSHYIQSQTGEIQGQNKYFQGTEGTRKASYVEQSGRSGRL 619
Query: 2991 ---------HSGIGHGQASSAVRDSGHRGYSGSQASDNEGHS-------------EDSDT 3028
+ G G S + +GH+ + + S + H + D
Sbjct: 620 SQQTPGQEGYQNQGQGFQSRDSQQNGHQVWEPEEDSQHHQHKLLAQIQQERPLCHKGRDW 679
Query: 3029 QSVSA---HGQAGSHQQSHQESARGRSGETSGHSGSFLYQVSTHEQSESSHGWTGPSTRG 3085
QS S+ H QA + +QSH E + E GH + +HE E G T
Sbjct: 680 QSCSSEQGHRQAQT-RQSHGEGLSHWAEEEQGHQ---TWDRHSHESQEGPCGTQDRRTHK 735
Query: 3086 RQGSRHEQAQDSSRHSASQYGQDTIRGHPGSSRGGRQGYHHE 3127
+ + + + + H S +D +R R HE
Sbjct: 736 DEQNHQRRDRQTHEHEQSHQRRDRQTHEDKQNRQRRDRQTHE 777
Score = 127 bits (318), Expect = 3e-28
Identities = 174/725 (24%), Positives = 272/725 (37%), Gaps = 83/725 (11%)
Query: 967 SRNHRGSAQEQSR------------HGSRHPRSHHEDRAGHGHSADSSRQSGTPHAETSS 1014
+++H G +Q R + R R HE+ + H + RQ G H
Sbjct: 91 NKSHGGRTSQQERGQEGAQDCKFPGNTGRQHRQRHEEERQNSHHSQPERQDGDSHHGQPE 150
Query: 1015 GGQAASSHEQARSSPGERHGSRHQQSADSSRHSGIPRRQASSAVRDSGHWGSSGSQASDS 1074
S H Q+ + H S+ ++ D H RQ D S S +
Sbjct: 151 RQDRDSHHGQSEKQDRDSHHSQPERQ-DRDSHHNQSERQDKDFSFDQSERQSQDSSSGKK 209
Query: 1075 EGHSEESDTQSVSGH-----GQDGPHQQSHQ-ESARDWSGGRSGRSGSFIYQVSTHEQSE 1128
H S GH + P Q SH +S R + S Q T++Q
Sbjct: 210 VSHKSTSGQAKWQGHIFALNRCEKPIQDSHYGQSERHTQQSETLGQASHFNQ--TNQQKS 267
Query: 1129 SAHGRTRTSTGRRQGSHHEQARDSSRHSASQEGQDTIRAHPGSRRGGRQGSHHEQSVDRS 1188
++ G+ G + S H + QD + + R G Q SH+ Q+ DR
Sbjct: 268 GSYCGQSERLGQELGCGQTDRQGQSSHYGQTDRQDQSYHYGQTDRQG-QSSHYSQT-DRQ 325
Query: 1189 GHSGSHHSHTTSQGRSDASHGQSGSRSASRQTRKDKQSGDGSRHSGSRHHEAASWADSSR 1248
G S SH+S QG+S + +GQ + + + G GS +S SS
Sbjct: 326 GQS-SHYSQPDRQGQS-SHYGQMDRKGQCYHYDQTNRQGQGSHYSQPNRQ-----GQSSH 378
Query: 1249 HSQVG-QEQSSGSRTSRHQGSSVSQDSDSERHSDDSERLSGSASRNHHGSSREQSRDGSR 1307
+ Q Q+QSS H G + QD S H +ER S+ H S ++ GS
Sbjct: 379 YGQPDTQDQSS------HYGQTDRQDQSS--HYGQTERQGQSS----HYSQMDRQGQGSH 426
Query: 1308 HPGFHQEDRASHGHSADSSRQSGTHHTESSSHGQAVSSHEQARSSPGE-RHGSRHQQSAD 1366
+ ++ ++SH D Q+ +H+ ++ GQ SSH G+ H S+ +
Sbjct: 427 YGQTDRQGQSSHYGQPDRQGQN-SHYGQTDRQGQ--SSHYGQTDRQGQSSHYSQPDKQGQ 483
Query: 1367 SSRHSGIGHRQASSAVRDSGHRGSSGSQVTNSEGHSEDSDTQSVSAH-GQAGPHQQSHKE 1425
SS + I + S H G Q +S H +D Q S H GQ QS
Sbjct: 484 SSHYGKIDRQD------QSYHYGQPDGQGQSS--HYGQTDRQGQSFHYGQPDRQGQSSHY 535
Query: 1426 SARGQSGESSGRSRSFLYQVSSHEQSESTHGQTAPSTGGRQGSRHEQARNSSRHSASQDG 1485
S + G+SS Y + + S +GQT + ++ SS + SQ G
Sbjct: 536 SQMDRQGQSSH------YGQTDRQGQSSHYGQTDRQGQSYHYGQTDRQGQSSHYIQSQTG 589
Query: 1486 QDTIRGHPGSSRGGRQGSYHEQSVDRSGHSGYHHSHTTPQGRSDASHGQSGPRSASRQTR 1545
+ I+G G +G+ V++SG SG S TP + GQ Q+R
Sbjct: 590 E--IQGQ-NKYFQGTEGTRKASYVEQSGRSG-RLSQQTPGQEGYQNQGQ------GFQSR 639
Query: 1546 NEEQSGD--GSRHSGSRHHEPSTRAGSSRHSQVGQGESAGSKTSRRQGSSVSQDRDSEG- 1602
+ +Q+G S+HH+ A + + S QG +Q R S G
Sbjct: 640 DSQQNGHQVWEPEEDSQHHQHKLLAQIQQERPLCHKGRDWQSCSSEQGHRQAQTRQSHGE 699
Query: 1603 ---HSEDSERRSESASRNHY----GSAREQSRHGSRNPRSHQ-EDRASHGHSAESSRQSG 1654
H + E+ ++ R+ + G Q R ++ ++HQ DR +H H R+
Sbjct: 700 GLSHWAEEEQGHQTWDRHSHESQEGPCGTQDRRTHKDEQNHQRRDRQTHEHEQSHQRRDR 759
Query: 1655 TRHAE 1659
H +
Sbjct: 760 QTHED 764
Score = 124 bits (311), Expect = 2e-27
Identities = 184/777 (23%), Positives = 272/777 (35%), Gaps = 112/777 (14%)
Query: 2609 HQEDRAGHGHSADSSRQSGTRHTQTSSGGQAASSHEQARSSAGERHGSHHQQ--SADSSR 2666
H+ D HG + G H Q ER SHH Q D
Sbjct: 87 HKLDNKSHGGRTSQQERGQEGAQDCKFPGNTGRQHRQRHEE--ERQNSHHSQPERQDGDS 144
Query: 2667 HSGIGHGQASSAVRDSGHRGYSGSQASDNEGHSEDSDTQSVSAHGQAGSHQQSHQESARG 2726
H HGQ RDS H S+ D + H + Q +H H QS ++
Sbjct: 145 H----HGQPERQDRDSHH---GQSEKQDRDSHHSQPERQDRDSH-----HNQSERQDK-- 190
Query: 2727 RSGETSGHSGSFLYQVSTHEQSESSHGWTGPSTRGRQGSRHEQAQDSSRHSASQDGQDTI 2786
F + S + +SS G S + G Q + + + QD+
Sbjct: 191 ----------DFSFDQSERQSQDSSSG-KKVSHKSTSGQAKWQGHIFALNRCEKPIQDS- 238
Query: 2787 RGHPGSSRGGRQGYHHEHSVDSSGHSGSHHSHTTSQGRSDASRGQS---GSRSASRTTRN 2843
H G S H+ S + H + T+Q +S + GQS G T
Sbjct: 239 --HYGQS--------ERHTQQSETLGQASHFNQTNQQKSGSYCGQSERLGQELGCGQTDR 288
Query: 2844 EEQS---GDGSRHSGSRHH-EASTHADISRHSQA-VQGQSEGSRRSRRQG-SSVSQDSDS 2897
+ QS G R S H+ + S +SQ QGQS + RQG SS D
Sbjct: 289 QGQSSHYGQTDRQDQSYHYGQTDRQGQSSHYSQTDRQGQSSHYSQPDRQGQSSHYGQMDR 348
Query: 2898 EGHSEDSERWSGSASRNHHGSAQEQLRDGSRHPRSHQEDRAGHGHSADSSRQSGTRHTQT 2957
+G ++ + +H+ Q S + + +D++ H D QS + + QT
Sbjct: 349 KGQCYHYDQTNRQGQGSHYSQPNRQ-GQSSHYGQPDTQDQSSHYGQTDRQDQS-SHYGQT 406
Query: 2958 SSGGQAASSHEQARSSAGERHGSHHQQSADS-----SRHSGIGHGQASSAVRDSGHRGYS 3012
GQ++ + R G +G +Q S R H + S H G +
Sbjct: 407 ERQGQSSHYSQMDRQGQGSHYGQTDRQGQSSHYGQPDRQGQNSHYGQTDRQGQSSHYGQT 466
Query: 3013 GSQASDNEGHSEDSDTQSVSAH-GQAGSHQQSH---QESARGRS---GETSGHSGSFLYQ 3065
Q + H D Q S+H G+ QS+ Q +G+S G+T SF Y
Sbjct: 467 DRQGQSS--HYSQPDKQGQSSHYGKIDRQDQSYHYGQPDGQGQSSHYGQTDRQGQSFHYG 524
Query: 3066 VSTHEQSESSHGWTGPSTRGRQGSRHEQAQDSSRHSASQYGQDTIRGHPGSSRGGRQGYH 3125
Q +SSH S RQG Q + +S YGQ +G Q YH
Sbjct: 525 -QPDRQGQSSH----YSQMDRQGQSSHYGQTDRQGQSSHYGQTDRQG---------QSYH 570
Query: 3126 HEHSVDSSGHSGSHHSHTTS--QGRSDASRGQSGSRSASRTTRNEEQSGDSSRHSVSRHH 3183
+ + D G S + T QG++ +G G+R AS EQSG S R S
Sbjct: 571 YGQT-DRQGQSSHYIQSQTGEIQGQNKYFQGTEGTRKASYV----EQSGRSGRLS----- 620
Query: 3184 EASTHADISRHSQAVQGQSEGSRRSRRQGSSV-SQDSDSEGHSE------DSERWSGSAS 3236
+ QGQ SR S++ G V + DS+ H ER
Sbjct: 621 ----QQTPGQEGYQNQGQGFQSRDSQQNGHQVWEPEEDSQHHQHKLLAQIQQERPLCHKG 676
Query: 3237 RNHRGSVQEQSRHGSRHPRSHHEDRAGHGHSADRSRQSGTRHAETSSGGQAASSHEQARS 3296
R+ + EQ H R H + H ++ Q+ RH+ S G + + R+
Sbjct: 677 RDWQSCSSEQG-HRQAQTRQSHGEGLSHWAEEEQGHQTWDRHSHESQEGPCGT--QDRRT 733
Query: 3297 SPGERHGSRHQQSADSSRHSGIPRGQASSAVRDSRHWGSSGSQASDSEGHSEESDTQ 3353
E++ R + S R + + H Q D + H +E + Q
Sbjct: 734 HKDEQNHQRRDRQTHEHEQSHQRRDRQT-------HEDKQNRQRRDRQTHEDEQNHQ 783
Score = 105 bits (263), Expect = 7e-22
Identities = 124/506 (24%), Positives = 193/506 (38%), Gaps = 55/506 (10%)
Query: 3525 QSAGPRTSRNQ-GSSVSQDSDSQGHSEDSERWSGSASRNHRGSAQEQSRDG-SRHPTSHH 3582
+S G RTS+ + G +QD G++ R R + +Q + +DG S H
Sbjct: 92 KSHGGRTSQQERGQEGAQDCKFPGNTGRQHRQRHEEERQNSHHSQPERQDGDSHHGQPER 151
Query: 3583 EDRAGHGHSAESSRQSGTHHAENSSGGQAASSHEQARSSAGERHGSHHQQSADSSRHSGI 3642
+DR H H + +HH++ + + ++ R +QS DSS +
Sbjct: 152 QDRDSH-HGQSEKQDRDSHHSQPERQDRDSHHNQSERQDKDFSFDQSERQSQDSSSGKKV 210
Query: 3643 GHGQASSAVRDSGH--------RGSSGSQASDSEGHSEDSDTQSVSAHGQAGPHQQSHQE 3694
H S + GH + S SE H++ S+T GQA Q++Q+
Sbjct: 211 SHKSTSGQAKWQGHIFALNRCEKPIQDSHYGQSERHTQQSETL-----GQASHFNQTNQQ 265
Query: 3695 STRGRSAGRSGRSGSFLYQVSTHEQSESAH-GRAG-PSTGGRQGSRHEQARDSSRHSASQ 3752
+ G G+S R G L T Q +S+H G+ G Q + S +
Sbjct: 266 KS-GSYCGQSERLGQELGCGQTDRQGQSSHYGQTDRQDQSYHYGQTDRQGQSSHYSQTDR 324
Query: 3753 EGQDTIRGHPGSRRGGRQG-SYHEQSVDRSGHSGSHHSHTTSQGRSDASHGQSGSRSASR 3811
+GQ + P RQG S H +DR G H+ T QG+ SH +R
Sbjct: 325 QGQSSHYSQP-----DRQGQSSHYGQMDRKGQC-YHYDQTNRQGQ--GSHYSQPNRQGQS 376
Query: 3812 ETRNEEQSGDGSRHSGSRHHEASTQADSSRHSQS-GQGESAGSRRSRRQG-SSVSQDSDS 3869
+ + D S H G + Q SS + Q+ QG+S+ + RQG S +D
Sbjct: 377 SHYGQPDTQDQSSHYG----QTDRQDQSSHYGQTERQGQSSHYSQMDRQGQGSHYGQTDR 432
Query: 3870 EAYPEDSERRSESASRNHHGSSREQSRDGSRHPGSSHRDTASHVQSSPVQSDSSTAKEHG 3929
+ + +H+G + Q + S H G + R S S P + S+
Sbjct: 433 QGQSSHYGQPDRQGQNSHYGQTDRQGQ--SSHYGQTDRQGQSSHYSQPDKQGQSS----- 485
Query: 3930 HFSSLS-QDSAYHSGIQSRGSPHSS---------SSYHYQSEGTERQKGQSGLVWRHGS- 3978
H+ + QD +YH G Q G SS S+HY + Q + R G
Sbjct: 486 HYGKIDRQDQSYHYG-QPDGQGQSSHYGQTDRQGQSFHYGQPDRQGQSSHYSQMDRQGQS 544
Query: 3979 --YGSADYDYGESGFRHSQHGSVSYN 4002
YG D S + + SY+
Sbjct: 545 SHYGQTDRQGQSSHYGQTDRQGQSYH 570
Score = 104 bits (260), Expect = 2e-21
Identities = 153/684 (22%), Positives = 248/684 (36%), Gaps = 87/684 (12%)
Query: 3387 LYQVSTHEQSESAHGRTRTSTGRRQGSHHEQARDSSRHSASQEGQDTIRGHPGSSRRGRQ 3446
L Q H+ +HG + R Q E A+D +T R H RQ
Sbjct: 81 LVQACYHKLDNKSHGGRTSQQERGQ----EGAQDCKFPG------NTGRQHRQRHEEERQ 130
Query: 3447 GSHYEQSVDRSGHSGSHHSHTTSQGRSDASRGQSGSRSASRQTRNDEQSGDGSRHSWSHH 3506
SH+ Q + G S HH Q R D+ GQS + E+ S H+ S
Sbjct: 131 NSHHSQPERQDGDS--HHGQPERQDR-DSHHGQSEKQDRDSHHSQPERQDRDSHHNQSER 187
Query: 3507 HEASTQADSSRHSQSGQGQSAGPRTSRNQGSSVSQDSDSQGHSEDSERWSGSASRNHRGS 3566
+ D S + Q S+G + S S S + QGH R +H G
Sbjct: 188 QDKDFSFDQSE--RQSQDSSSGKKVSHK---STSGQAKWQGHIFALNRCEKPIQDSHYGQ 242
Query: 3567 AQEQSRDGSRHPTSHHEDRAGHGHSAESSRQSGTHHAENSSGGQAASSHEQARSSAGERH 3626
++ ++ + H ++ + ++SG++ ++ GQ + R +
Sbjct: 243 SERHTQQSETLGQASHFNQT-------NQQKSGSYCGQSERLGQELGCGQTDRQGQSSHY 295
Query: 3627 GSHHQQSADSSRHSGIGHGQASSAVRDSGHRGSSGSQASDSEGHSEDSDTQSVSAHGQAG 3686
G +Q D S H G Q S+ R S S + + S + GQ
Sbjct: 296 GQTDRQ--DQSYHYGQTDRQGQSSHYSQTDRQGQSSHYSQPDRQGQSSHYGQMDRKGQCY 353
Query: 3687 PHQQSHQESTRGRSAGRSGRSGSFLYQVSTHEQSESAHGRAGPSTGGRQGSRHEQARDSS 3746
+ Q++++ +G + R G + Q +S+H G + Q S + Q +
Sbjct: 354 HYDQTNRQG-QGSHYSQPNRQGQSSHYGQPDTQDQSSH--YGQTDRQDQSSHYGQ---TE 407
Query: 3747 RHSASQEGQDTIRGHPGSRRG--GRQG-SYHEQSVDRSGHSGSHHSHTTSQGRSDASHGQ 3803
R S R GS G RQG S H DR G + SH+ T QG+S + +GQ
Sbjct: 408 RQGQSSHYSQMDRQGQGSHYGQTDRQGQSSHYGQPDRQGQN-SHYGQTDRQGQS-SHYGQ 465
Query: 3804 SGSRSASRETRNEEQSGDGSRHSGSRHHEASTQADSSRH--SQSGQGESAGSRRSRRQGS 3861
+ + S ++ G S H+ + D S H GQG+S+ ++ RQG
Sbjct: 466 TDRQGQSSHYSQPDKQGQSS------HYGKIDRQDQSYHYGQPDGQGQSSHYGQTDRQGQ 519
Query: 3862 SVSQ-DSDSEAYPEDSERRSESASRNHHGSSREQSRDGSRHPGSSHRDTASHVQSSPVQS 3920
S D + + +H+G + Q + S H G + R S+
Sbjct: 520 SFHYGQPDRQGQSSHYSQMDRQGQSSHYGQTDRQGQ--SSHYGQTDRQGQSY-------- 569
Query: 3921 DSSTAKEHGHFSSLSQDSAYHSGIQSR-GSPHSSSSYHYQSEGTER-----QKGQSGLVW 3974
+G Q S Y IQS+ G + Y +EGT + Q G+SG +
Sbjct: 570 ------HYGQTDRQGQSSHY---IQSQTGEIQGQNKYFQGTEGTRKASYVEQSGRSGRL- 619
Query: 3975 RHGSYGSADYDYGESGFRHSQHGSVSYNSNPVVFKERSDICKASAFGKDHPRYYATYINK 4034
+ G+ G+++ G S +S + + + + H I +
Sbjct: 620 -------SQQTPGQEGYQNQGQGFQSRDSQ----QNGHQVWEPEEDSQHHQHKLLAQIQQ 668
Query: 4035 DPGLCGHSSD---ISKQLGFSQSQ 4055
+ LC D S + G Q+Q
Sbjct: 669 ERPLCHKGRDWQSCSSEQGHRQAQ 692
Score = 47.0 bits (110), Expect = 4e-04
Identities = 56/237 (23%), Positives = 87/237 (36%), Gaps = 44/237 (18%)
Query: 3830 HHEASTQADSSRHSQSGQGESAG--------SRRSRRQGSSVSQDSDSEAYPEDSERRSE 3881
+H+ ++ R SQ +G+ + R RQ + + + PE + S
Sbjct: 86 YHKLDNKSHGGRTSQQERGQEGAQDCKFPGNTGRQHRQRHEEERQNSHHSQPERQDGDS- 144
Query: 3882 SASRNHHGSSREQSRDGSRHPGSSHRDTASHVQSSPVQSDSSTAKEHGHFSSLSQDSAYH 3941
HHG Q RD S H S +D SH S P + D ++ H S QD +
Sbjct: 145 -----HHGQPERQDRD-SHHGQSEKQDRDSH-HSQPERQD----RDSHHNQSERQDKDFS 193
Query: 3942 SGIQSRGSPHSSSSYHYQSEGTERQKGQSGLVWRHGSYGSA--DYDYGESGFRHSQHGSV 3999
R S SSS + T Q G ++ D YG+S RH+Q
Sbjct: 194 FDQSERQSQDSSSGKKVSHKSTSGQAKWQGHIFALNRCEKPIQDSHYGQSE-RHTQQSET 252
Query: 4000 SYNSNPVVFKERSDICKASAFGKDHPRYYATYINKDPGLCGHSSDISKQLGFSQSQR 4056
+ +AS F + + + +Y CG S + ++LG Q+ R
Sbjct: 253 --------------LGQASHFNQTNQQKSGSY-------CGQSERLGQELGCGQTDR 288
>gi|223890219 RNA binding motif protein, X-linked-like 3 [Homo
sapiens]
Length = 1067
Score = 145 bits (365), Expect = 1e-33
Identities = 238/1030 (23%), Positives = 382/1030 (37%), Gaps = 170/1030 (16%)
Query: 1840 GSHHSHTTSQERSDVSRGQSGSRSV-SRQTRNEKQSGDGSRHSGSRHHEASSRADSSRHS 1898
GS SQ R D RG +G + + ++ G RH S H+ ++ SS
Sbjct: 115 GSSPQRPPSQGRPDDGRGYAGYFDLWPYRAPMPRKRGPPPRHWASPPHKRAT--PSSLAH 172
Query: 1899 QVGQG-QSSGPRTSRNQGSSVSQDSDSQG--HSEDSERWS-----GSASRNHLGSAWEQS 1950
VG G + P S G S Q G H R S GS + W Q
Sbjct: 173 SVGCGMRGKAPTVSGQDGYSGLQPRRWAGPPHKRAVPRSSLARIGGSGMPGKAPAVWGQD 232
Query: 1951 --------------RD-GSRHPGSHHEDRAGHGHSA--------DSSRQSGTR-----HT 1982
RD G P R +GHS+ Q+G R +T
Sbjct: 233 GYSGPRVREPLPPCRDPGDFVPALRDYSRRYYGHSSVPDYRPLRGDGNQNGYRGRDHEYT 292
Query: 1983 ESSSRGQAASSHEQARSSAGE-----------RHGSHHQLQSADSSRHSGIGHGQASSAV 2031
+ S+G S E +S G +G + + + G++S A+
Sbjct: 293 DHPSKG---SYREPLKSYGGPCGAAPVWGTPPSYGGGCRYEEYQGNSPDACSEGRSSEAL 349
Query: 2032 ---------RDSGHRGYSGSQASDSEGHSEDSDTQSVSAQGKAGPHQQSHKESARGQSGE 2082
RD + YSG ++S S G+S G+ G +++ S SG
Sbjct: 350 PVVLPDAYSRDHSPKAYSGGRSSSSNGYSRSD------RYGEEGCYEEYRGRSPDAHSGG 403
Query: 2083 SSGRSGSF--LYQVSTHEQSESTHGQSAPS-TGGRQGSHYDQAQDSSRHSASQEGQDTIR 2139
+ S S+ + + E G+S + +GGR + + + +S G D+
Sbjct: 404 RNSSSNSYGQSHHYGGEGRYEEYRGRSHEARSGGRSTDAHSRGRSDDAYSG---GHDSSS 460
Query: 2140 GHPGPSRGGRQGSHQEQSVDRSG-------HSGSHHSHTTSQ-----GRSDASRGQSGSR 2187
GGR +Q +S+D + +SG H + + S G + +RG S
Sbjct: 461 WSDCCGGGGRYEEYQGRSLDANSGGCSPEAYSGGHDNSSWSDRYGVGGHYEENRGHSLDA 520
Query: 2188 SASRKTYDKEQSGDGSRHSGSHHHEASSWADSSRHSLVGQGQSSGPRTSRPRGSSVSQDS 2247
++ ++ D HSG H ++S+ S R+ G+ + G R+ S D+
Sbjct: 521 NSGGRSPDT--------HSGGHSSSSNSYGQSHRYGGEGRYEYRG-RSHDAHSGGCSADA 571
Query: 2248 DSEGH--SEDSERRSGSASRNHHGSAQEQSRDGSRHPRSHHEDRAGHGHSAESSRQSGTH 2305
S GH S S R G + + G R P ++ GH S+ S R G
Sbjct: 572 YSGGHDSSSQSNRYGGGGCYEEYRGRSLDANSGGRSPNAYS---GGHDSSSWSHRYGGGG 628
Query: 2306 HAENSSGGQAASSHEQARSSAGERHGSHHQQSADSSRHSGIGHGQASSAVRDSGHRG--- 2362
E G ++ ++ RS + + H S S+ + G G R +RG
Sbjct: 629 RYEEYRG-RSLDANSGGRSP--DAYSGGHDSSGQSNCYGGGG--------RYEEYRGRLL 677
Query: 2363 --SSGSQASDSEGHSEDSDTQSVSAHGQAGPHQQSHQESTRGRSAGRSGRSGSFLYQVST 2420
+SG ++ D+ DS +QS + +G G +++ S S GRS + S + S+
Sbjct: 678 DANSGGRSPDAYSGGHDSSSQS-NRYGGGGRYEEYRGHSLDANSGGRSPDTYSRGHDSSS 736
Query: 2421 HEQSESAHGRT-GTSTGGRQGSHHKQARDSSRHSTSQEGQDTIHGHPGSS----SGGRQG 2475
GR+ ++ GR + DSS S G + G S SGGR
Sbjct: 737 QSDHYGGGGRSLDANSSGRLPDAYSGGHDSSSRSHRYGGGGRYEEYRGRSLDANSGGRSP 796
Query: 2476 SHYEQLVDRSGH-SGSHHSHTTSQGRSDASHGHSGSRSASRQTRNDEQSGDGSRHSGSRH 2534
+ Y GH S S + GR + + GHS ++ + N + G R S S
Sbjct: 797 NAYS-----GGHNSSSRNDPCRGGGRYEENRGHSLDANSGGHSPN---AYSGGRDSSSNS 848
Query: 2535 HEASSRADSSGHSQVGQGQSEGPRTSRNWGSSFSQDSDSQGHSEDSERWSGSASRNHH-- 2592
++ S R GH + +G+S + + S D ++ +S + +S S R+ H
Sbjct: 849 YDRSHRYGGGGHYEEYRGRSHDTHSRGRSPDAHSGDHYTEAYSRGRDSFSNSYGRSDHYG 908
Query: 2593 -GSAQEQLRDGSRHPRSHQEDRAGHGHSADSSRQSGTRHTQTSSGGQAASSHEQARSSAG 2651
G E+ + R P ++ G G +SS S R + GG+ +E+ R +
Sbjct: 909 RGGCYEEYQ--GRSPNAY-----GGGRGLNSSNNSHGRSHRYGGGGR----YEEYRGPSP 957
Query: 2652 ERHGSHHQQSAD----SSRHSGIGHGQASSAVRDSGHRGYSGSQASDNEGHSEDSDTQSV 2707
+ H S S R+ G GH Y Q S + +S D D +S
Sbjct: 958 DAHSGGRDSSIKSYGLSDRYGGGGH--------------YEEYQGSLPDAYSGDHD-RSS 1002
Query: 2708 SAHGQAGSHQQSHQESARGRSG-ETSGHSGSFLYQVSTHEQSESSHGWTGPSTRGRQGSR 2766
+++G++ + + R G +GS S S G P GRQG R
Sbjct: 1003 NSYGRSDRYSRGRDRVGRPDRGLPLPMETGS-----PPLHDSYSRSGCRVPRGGGRQGGR 1057
Query: 2767 HEQAQDSSRH 2776
E+ + SR+
Sbjct: 1058 FERGEGRSRY 1067
Score = 143 bits (360), Expect = 4e-33
Identities = 250/1060 (23%), Positives = 380/1060 (35%), Gaps = 164/1060 (15%)
Query: 597 SSRHSQVGQGQSSGPRTSRNQ--GSSVSQDSDSQGHSEDSERWSGSASRNHHGSAQEQSR 654
SSR G S R S G S Q SQG +D ++G + + + R
Sbjct: 91 SSRWVPPTPGSGSRSRFSHRTRGGGSSPQRPPSQGRPDDGRGYAGYFDLWPYRAPMPRKR 150
Query: 655 DGS-RHPRSHHEDRAGHGHSADSSRKSGTRHTQNSSSGQAASSHEQARSSAGERHGSRHQ 713
RH S RA A S G R + SGQ S Q R AG H +
Sbjct: 151 GPPPRHWASPPHKRATPSSLAHSVG-CGMRGKAPTVSGQDGYSGLQPRRWAGPPH--KRA 207
Query: 714 LQSADSSRHSGTGHGQASSAVRDSGHRGSSGSQATDS---------------------EG 752
+ + +R G+G + AV G G SG + + G
Sbjct: 208 VPRSSLARIGGSGMPGKAPAVW--GQDGYSGPRVREPLPPCRDPGDFVPALRDYSRRYYG 265
Query: 753 HSEDSDTQSVSGHG-QAGHHQQSHQESARDRSGERSRRSGSFLYQVSTHKQSESSHG--- 808
HS D + + G G Q G+ + H+ + G ++++ S+G
Sbjct: 266 HSSVPDYRPLRGDGNQNGYRGRDHEYTDHPSKG--------------SYREPLKSYGGPC 311
Query: 809 -----W-TGPSTGVRQGSHHEQARDNSRHSASQDGQDTIRGHPGSSRRGRQGSHHEQSVD 862
W T PS G G +E+ + NS P + GR S V
Sbjct: 312 GAAPVWGTPPSYG--GGCRYEEYQGNS---------------PDACSEGRS-SEALPVVL 353
Query: 863 RSGHSGSHHSHTTSQGRSDASRGQSGS-RSASRTTRNEEQSRDGSRHSGSRHHEASSHAD 921
+S H S GRS +S G S S R E + R HSG R+ ++S+
Sbjct: 354 PDAYSRDHSPKAYSGGRSSSSNGYSRSDRYGEEGCYEEYRGRSPDAHSGGRNSSSNSYGQ 413
Query: 922 ISRHSQAGQGQSEGSRTSRRQGSSVSQDSDSEGHSED-------SERWS-----GSASRN 969
+ G+ + R+ + S D+ S G S+D S WS G
Sbjct: 414 SHHYGGEGRYEEYRGRSHEARSGGRSTDAHSRGRSDDAYSGGHDSSSWSDCCGGGGRYEE 473
Query: 970 HRGSAQEQSRHGSR-------HPRSHHEDRAGHGHSADSSRQSGTPHAETSSGGQAASSH 1022
++G + + + G H S DR G G + +R + +SGG++ +H
Sbjct: 474 YQGRSLDANSGGCSPEAYSGGHDNSSWSDRYGVGGHYEENRGHSL---DANSGGRSPDTH 530
Query: 1023 EQARSSPGERHGSRHQQSADSSRHSGIPRRQASSAVRDSGHWGSSGSQASDSEGHSEESD 1082
SS +G H R+ G R + R H SG ++D+ +S
Sbjct: 531 SGGHSSSSNSYGQSH-------RYGGEGRYE----YRGRSHDAHSGGCSADAYSGGHDSS 579
Query: 1083 TQSVSGHGQDGPHQQSHQESARDWSGGRSGRSGSFIYQVSTHEQSESAHGRTRTSTGRRQ 1142
+QS + +G G +++ S SGGRS + S + S+ GR GR
Sbjct: 580 SQS-NRYGGGGCYEEYRGRSLDANSGGRSPNAYSGGHDSSSWSHRYGGGGRYEEYRGRSL 638
Query: 1143 GSHHEQARDSSRHSASQEGQDTIRAHPGSRRGGRQGSHHEQSVDRSGHSGSHHSHTTSQG 1202
++ R +S + + G GGR + + +D + S G
Sbjct: 639 DAN-SGGRSPDAYSGGHDSSGQSNCYGG---GGRYEEYRGRLLDAN-----------SGG 683
Query: 1203 RSDASHGQSGSRSASRQTRKDKQSGDGSRHSGSRHHEAASWADSSRHSQVGQEQSSGSRT 1262
RS ++ SG +S Q+ + G G R+ R H + + + S S++
Sbjct: 684 RSPDAY--SGGHDSSSQSNR---YGGGGRYEEYRGHSLDANSGGRSPDTYSRGHDSSSQS 738
Query: 1263 SRHQGSSVSQDSDSERHSDDSERLSGSASRNHHGSSREQSRDGSRHPGFHQEDRASHGHS 1322
+ G S D++S S RL + S H SSR G G ++E R G S
Sbjct: 739 DHYGGGGRSLDANS------SGRLPDAYSGGHDSSSRSHRYGGG---GRYEEYR---GRS 786
Query: 1323 ADSSRQSGTHHTESSSHGQAVSSHEQARSSPGERHGSRHQQSADSSRHSG---IGHRQAS 1379
D++ + + S H + S ++ R H A+S HS G R +S
Sbjct: 787 LDANSGGRSPNAYSGGHNSS-SRNDPCRGGGRYEENRGHSLDANSGGHSPNAYSGGRDSS 845
Query: 1380 SAVRDSGHRGSSGSQVTNSEGHSEDSDTQSVSAHGQAGPHQQSHKESARGQSGESSGRSR 1439
S D HR G G S D+ ++ S +G H R S GRS
Sbjct: 846 SNSYDRSHRYGGGGHYEEYRGRSHDTHSRGRSPDAHSGDHYTEAYSRGRDSFSNSYGRSD 905
Query: 1440 SF-------LYQVSSH---------EQSESTHGQTAPSTGGRQGSRHEQARNSSRHSASQ 1483
+ YQ S S ++HG++ G G R+E+ R S + S
Sbjct: 906 HYGRGGCYEEYQGRSPNAYGGGRGLNSSNNSHGRSHRYGG---GGRYEEYRGPSPDAHSG 962
Query: 1484 DGQDTIRGHPGSSRGGRQGSYHE-QSVDRSGHSGYHHSHTTPQGRSDA-SHGQSGPRSAS 1541
+I+ + S R G G Y E Q +SG H + GRSD S G+
Sbjct: 963 GRDSSIKSYGLSDRYGGGGHYEEYQGSLPDAYSGDHDRSSNSYGRSDRYSRGRDRVGRPD 1022
Query: 1542 RQTRNEEQSGDGSRH-SGSRHHEPSTRAGSSRHSQVGQGE 1580
R ++G H S SR R G + + +GE
Sbjct: 1023 RGLPLPMETGSPPLHDSYSRSGCRVPRGGGRQGGRFERGE 1062
Score = 140 bits (352), Expect = 3e-32
Identities = 243/984 (24%), Positives = 352/984 (35%), Gaps = 150/984 (15%)
Query: 2564 GSSFSQDSDSQGHSEDSERWSGSASRNHHGSAQEQLRDGS-RHPRSHQEDRAGHGHSADS 2622
G S Q SQG +D ++G + + + R RH S RA A S
Sbjct: 114 GGSSPQRPPSQGRPDDGRGYAGYFDLWPYRAPMPRKRGPPPRHWASPPHKRATPSSLAHS 173
Query: 2623 SRQSGTRHTQTSSGGQAASSHEQARSSAGERHGSHHQQSADSSRHSGIG-HGQASSAVRD 2681
G R + GQ S Q R AG H +++ S + IG G A
Sbjct: 174 VG-CGMRGKAPTVSGQDGYSGLQPRRWAGPPH----KRAVPRSSLARIGGSGMPGKAPAV 228
Query: 2682 SGHRGYSGSQASDN---------------------EGHSEDSDTQSVSAHGQAGSHQQSH 2720
G GYSG + + GHS D + + G +
Sbjct: 229 WGQDGYSGPRVREPLPPCRDPGDFVPALRDYSRRYYGHSSVPDYRPLRGDG--------N 280
Query: 2721 QESARGRSGETSGHSGSFLYQVSTHEQSESSHG-------WTGPSTRGRQGSRHEQAQDS 2773
Q RGR E + H Y+ E +S G W P + G G R+E+ Q +
Sbjct: 281 QNGYRGRDHEYTDHPSKGSYR----EPLKSYGGPCGAAPVWGTPPSYGG-GCRYEEYQGN 335
Query: 2774 SRHSASQDGQDTIRGHPGSSRGGRQGYHHEHSVDSSGHSGSHHSHTTSQGRSDASRGQSG 2833
S + S+ R Y +HS +SG S + RSD G+ G
Sbjct: 336 SPDACSEG-----RSSEALPVVLPDAYSRDHS--PKAYSGGRSSSSNGYSRSDRY-GEEG 387
Query: 2834 SRSASRTTRNEEQSGDGSRHSGSRHHEASTHADISRHSQAVQGQSEGSRRSRRQGSSVSQ 2893
R + SG R+S S + S H + +G+S +R R + S+
Sbjct: 388 CYEEYRGRSPDAHSG--GRNSSSNSYGQSHHYGGEGRYEEYRGRSHEARSGGRSTDAHSR 445
Query: 2894 DSDSEGHS--EDSERWSG--------------SASRNHHGSAQEQLRDGSRHPRSHQEDR 2937
+ +S DS WS S N G + E G H S DR
Sbjct: 446 GRSDDAYSGGHDSSSWSDCCGGGGRYEEYQGRSLDANSGGCSPEAYSGG--HDNSSWSDR 503
Query: 2938 AG--------HGHSADSSRQSGTRHTQTSSGGQAASSHEQARSSAGERHGSHHQQSADSS 2989
G GHS D++ SG R T SGG ++SS+ +S G + +
Sbjct: 504 YGVGGHYEENRGHSLDAN--SGGRSPDTHSGGHSSSSNSYGQSHRYGGEGRYEYRGRSHD 561
Query: 2990 RHSGIGHGQASSAVRDS---GHRGYSGSQASDNEGHSEDSDTQSVSAHGQAGSHQQ---S 3043
HSG A S DS +R G + G S D+++ S + +G H S
Sbjct: 562 AHSGGCSADAYSGGHDSSSQSNRYGGGGCYEEYRGRSLDANSGGRSPNAYSGGHDSSSWS 621
Query: 3044 HQESARGRSGETSGHSGSFLYQVSTHEQSESSHGWTGPSTRGRQGSRHEQAQDS--SRHS 3101
H+ GR E G S + + H +G S G R+E+ + +S
Sbjct: 622 HRYGGGGRYEEYRGRSLDANSGGRSPDAYSGGHDSSGQSNCYGGGGRYEEYRGRLLDANS 681
Query: 3102 ASQYGQDTIRGHPGSSRGGRQGYHHEHSVDSSGHSGSHHSHTTSQGRSDASRGQSGSRSA 3161
+ GH SS+ R G G + H+ SG RS
Sbjct: 682 GGRSPDAYSGGHDSSSQSNRYG--------GGGRYEEYRGHSLD--------ANSGGRSP 725
Query: 3162 SRTTRNEEQSGDSSRH-SVSRHHEASTHADISRHSQAVQGQSEGSRRSRRQGSSVSQDSD 3220
+R + S S + R +A++ R A G + S RS R G + +
Sbjct: 726 DTYSRGHDSSSQSDHYGGGGRSLDANSS---GRLPDAYSGGHDSSSRSHRYGGG-GRYEE 781
Query: 3221 SEGHSEDSERWSGSASRN-HRGSVQEQSRHGSRHPRSHHEDRAGHGHSADRSRQSGTRHA 3279
G S D+ SG S N + G SR+ +E+ GH A+ SG
Sbjct: 782 YRGRSLDAN--SGGRSPNAYSGGHNSSSRNDPCRGGGRYEENRGHSLDAN----SGGHSP 835
Query: 3280 ETSSGGQAASSHEQARSSPGERHGSRHQQSADSSRHSGIPRGQASSAVRDSRHWGSSGSQ 3339
SGG+ +SS+ RS G H + H RG++ A H G ++
Sbjct: 836 NAYSGGRDSSSNSYDRSH--RYGGGGHYEEYRGRSHDTHSRGRSPDA-----HSGDHYTE 888
Query: 3340 ASDSEGHSEESDTQSVSGH-GQAGPHQQSHQESARDRSGGRSGRSGSFLYQVSTHEQSES 3398
A S G S++ S H G+ G +++ S GGR S S +
Sbjct: 889 AY-SRGRDSFSNSYGRSDHYGRGGCYEEYQGRSPNAYGGGRGLNS------------SNN 935
Query: 3399 AHGRTRTSTGRRQGSHHEQARDSSRHSASQEGQDTIRGHPGSSRRGRQGSHYE--QSVDR 3456
+HGR+ G G +E+ R S + S +I+ + S R G G HYE Q
Sbjct: 936 SHGRSHRYGG---GGRYEEYRGPSPDAHSGGRDSSIKSYGLSDRYG-GGGHYEEYQGSLP 991
Query: 3457 SGHSGSHHSHTTSQGRSDA-SRGQ 3479
+SG H + S GRSD SRG+
Sbjct: 992 DAYSGDHDRSSNSYGRSDRYSRGR 1015
Score = 137 bits (346), Expect = 2e-31
Identities = 240/1000 (24%), Positives = 360/1000 (36%), Gaps = 151/1000 (15%)
Query: 290 RKRRGSRVSQDRDSEGHSEDSERHSGSASRNHHGSAWEQSRDGS-RHPRSHDEDRASHGH 348
R R G Q S+G +D ++G + + + R RH S RA+
Sbjct: 110 RTRGGGSSPQRPPSQGRPDDGRGYAGYFDLWPYRAPMPRKRGPPPRHWASPPHKRATPSS 169
Query: 349 SADSSRQSGTRHAETSSRGQTASSHEQARSSPGERHGSGHQQSADSSRHSATGRGQASSA 408
A S G R + GQ S Q R G H +S S G G A
Sbjct: 170 LAHSVG-CGMRGKAPTVSGQDGYSGLQPRRWAGPPHKRAVPRS---SLARIGGSGMPGKA 225
Query: 409 VSDRGHRGSSGSQASDS---------------------EGHSENSDTQSVSGHGKAGLRQ 447
+ G G SG + + GHS D + + G G
Sbjct: 226 PAVWGQDGYSGPRVREPLPPCRDPGDFVPALRDYSRRYYGHSSVPDYRPLRGDG------ 279
Query: 448 QSHQESTRGRSGERSGRSGSSLYQ--VSTHEQPDSAHGRTGTSTGGRQGSHHEQARDSSR 505
+Q RGR E + Y+ + ++ P A GT G +E+ + +S
Sbjct: 280 --NQNGYRGRDHEYTDHPSKGSYREPLKSYGGPCGAAPVWGTPPSYGGGCRYEEYQGNSP 337
Query: 506 HSASQEGQDTIRGHPGSSRGGRQGSHHEQSVNRSGHSGSHHSHTTSQGRSDASHGQSGSR 565
+ S+ GR S V +S H S GRS +S+G S S
Sbjct: 338 DACSE---------------GRS-SEALPVVLPDAYSRDHSPKAYSGGRSSSSNGYSRSD 381
Query: 566 SASRQTRNEEQSG-DGTRHSGSRHHEASSQADSSRHSQVGQGQSSGPRTSRNQGSSVSQD 624
+ EE G HSG R+ ++S S + G+ + R+ + S D
Sbjct: 382 RYGEEGCYEEYRGRSPDAHSGGRNSSSNSYGQSHHYGGEGRYEEYRGRSHEARSGGRSTD 441
Query: 625 SDSQGHSE-------DSERWSG-SASRNHHGSAQEQSRDGSRHPRSHHEDRAGHGHSADS 676
+ S+G S+ DS WS + Q +S D + S GH +S+ S
Sbjct: 442 AHSRGRSDDAYSGGHDSSSWSDCCGGGGRYEEYQGRSLDANSGGCSPEAYSGGHDNSSWS 501
Query: 677 SRKS-GTRHTQN-------SSSGQAASSHEQARSSAGERHGSRHQLQSADSSRHSGTGHG 728
R G + +N +S G++ +H SS+ +G H R+ G G
Sbjct: 502 DRYGVGGHYEENRGHSLDANSGGRSPDTHSGGHSSSSNSYGQSH--------RYGGEGRY 553
Query: 729 QASSAVRDSGHRGSSGSQATDSEGHSEDSDTQSVSGHGQAGHHQQSHQESARDRSGERSR 788
+ R H SG + D+ DS +QS + +G G +++ S SG RS
Sbjct: 554 E----YRGRSHDAHSGGCSADAYSGGHDSSSQS-NRYGGGGCYEEYRGRSLDANSGGRSP 608
Query: 789 RSGSFLYQVSTHKQSESSHGWTGPSTGVRQGSHHEQARDNSRHSASQD---------GQD 839
+ S H S SH + G G R + ++ D + S D GQ
Sbjct: 609 NAYS-----GGHDSSSWSHRYGG---GGRYEEYRGRSLDANSGGRSPDAYSGGHDSSGQS 660
Query: 840 TIRGHPG--SSRRGRQGSHHEQSVDRSGHSGSHHSHTTSQ-----GRSDASRG-----QS 887
G G RGR + +SG H S + S GR + RG S
Sbjct: 661 NCYGGGGRYEEYRGRLLDANSGGRSPDAYSGGHDSSSQSNRYGGGGRYEEYRGHSLDANS 720
Query: 888 GSRSASRTTRNEEQSRDGSRH-SGSRHHEASSHADISRHSQAGQGQSEGSRTSRRQGSSV 946
G RS +R + S + G R +A+S R A G + S S R G
Sbjct: 721 GGRSPDTYSRGHDSSSQSDHYGGGGRSLDANSS---GRLPDAYSGGHDSSSRSHRYGGG- 776
Query: 947 SQDSDSEGHSEDSERWSGSASRN-HRGSAQEQSRHGSRHPRSHHEDRAGHGHSADSSRQS 1005
+ + G S D+ SG S N + G SR+ +E+ GHS D++
Sbjct: 777 GRYEEYRGRSLDAN--SGGRSPNAYSGGHNSSSRNDPCRGGGRYEE--NRGHSLDANSGG 832
Query: 1006 GTPHAETSSGGQAASSHEQARSSPGERHGSRHQQSADSSRHSGIPRRQASSAVRDSGHWG 1065
+P+A SGG+ +SS+ RS R+G R R S H+
Sbjct: 833 HSPNA--YSGGRDSSSNSYDRS---HRYGGGGHYEEYRGRSHDTHSRGRSPDAHSGDHYT 887
Query: 1066 SSGSQASDSEGHSEESDTQSVSGHGQDGPHQQSHQESARDWSGGRSGRSGSFIYQVSTHE 1125
+ S+ DS +S +G+ G +++ S + GGR S
Sbjct: 888 EAYSRGRDSFSNSYGRSDH----YGRGGCYEEYQGRSPNAYGGGRGLNS----------- 932
Query: 1126 QSESAHGRTRTSTGRRQGSHHEQARDSSRHSASQEGQDTIRAHPGSRRGGRQGSHHE-QS 1184
S ++HGR+ G G +E+ R S + S +I+++ S R G G + E Q
Sbjct: 933 -SNNSHGRSHRYGG---GGRYEEYRGPSPDAHSGGRDSSIKSYGLSDRYGGGGHYEEYQG 988
Query: 1185 VDRSGHSGSHHSHTTSQGRSDASHGQSGSRSASRQTRKDK 1224
+SG H + S GRSD SR R R D+
Sbjct: 989 SLPDAYSGDHDRSSNSYGRSDRY-----SRGRDRVGRPDR 1023
Score = 137 bits (344), Expect = 3e-31
Identities = 197/804 (24%), Positives = 303/804 (37%), Gaps = 98/804 (12%)
Query: 1392 GSQVTNSEGHSEDSDTQSVSAHG------QAGPHQQSHKESARGQSGESSGRSRSFLYQV 1445
G + +G+S D+ ++ S+ A S K + G+S S+G SRS Y
Sbjct: 326 GCRYEEYQGNSPDACSEGRSSEALPVVLPDAYSRDHSPKAYSGGRSSSSNGYSRSDRYGE 385
Query: 1446 SSHEQSESTHGQTAPSTGGRQGSRHEQARNSSRHSASQDGQDTIRGHPGSSR-GGRQGSY 1504
+ A S GGR S + + S H + + RG +R GGR
Sbjct: 386 EGCYEEYRGRSPDAHS-GGRNSSSNSYGQ--SHHYGGEGRYEEYRGRSHEARSGGRSTDA 442
Query: 1505 HEQSVDRSGHSGYHHSHTTPQGRSDASHGQSGPRSASRQTRNEEQSGDGSRHSGSRHHEP 1564
H + +SG H S + SD G G R Q R+ + + G P
Sbjct: 443 HSRGRSDDAYSGGHDSSSW----SDCCGG--GGRYEEYQGRSLDANSGGC--------SP 488
Query: 1565 STRAGSSRHSQVGQGESAGSKTSRRQGSSVSQDRDSEGHSEDSERRSESASRNHYGSARE 1624
+G +S G +G S+ D +S G S D+ S+S N YG +
Sbjct: 489 EAYSGGHDNSSWSDRYGVGGHYEENRGHSL--DANSGGRSPDTHSGGHSSSSNSYGQSHR 546
Query: 1625 QSRHGSRNPRSHQEDRASHGHSAESSRQSGTRHAETSSGGQAASSQEQARSSPGERHGSR 1684
G R D S G SA++ SGG +SSQ G
Sbjct: 547 YGGEGRYEYRGRSHDAHSGGCSADAY-----------SGGHDSSSQSNRYGG-----GGC 590
Query: 1685 HQQSADSSTDSGTGRRQDSSVVG--DSGN---RGSSGSQASDSEGHSEESDTQSVSAHGQ 1739
+++ S D+ +G R ++ G DS + R G + + G S ++++ S
Sbjct: 591 YEEYRGRSLDANSGGRSPNAYSGGHDSSSWSHRYGGGGRYEEYRGRSLDANSGGRSPDAY 650
Query: 1740 AGPHQQSHQESTRGQSGERSGRSGSFLYQVSTHEQSESAHGRTGPST-----GGRQRSRH 1794
+G H S Q + G G G L S ++ G S+ GG R
Sbjct: 651 SGGHDSSGQSNCYGGGGRYEEYRGRLLDANSGGRSPDAYSGGHDSSSQSNRYGGGGRYEE 710
Query: 1795 EQARDSSRHSASQEGQDTIRGHPGSSRGGRQGSHYEQ-SVDSSG-----HSGSHHSHTTS 1848
+ +S + RGH SS+ G +SSG +SG H S + S
Sbjct: 711 YRGHSLDANSGGRSPDTYSRGHDSSSQSDHYGGGGRSLDANSSGRLPDAYSGGHDSSSRS 770
Query: 1849 QERSDVSRGQSGSRSVSRQTRNEKQSGDGSRHSGSRHHEASSRADSSRHSQVGQGQSSGP 1908
G G R + SG S ++ S H +SSR D R G
Sbjct: 771 HRY-----GGGGRYEEYRGRSLDANSGGRSPNAYSGGHNSSSRNDPCR---------GGG 816
Query: 1909 RTSRNQGSSVSQDSDSQGHSEDSERWSGSASRNHLGSAWEQS-RDGSRHPGSHHEDRAGH 1967
R N+G S+ D++S GHS ++ S R+ +++++S R G G H+E+ G
Sbjct: 817 RYEENRGHSL--DANSGGHSPNAY----SGGRDSSSNSYDRSHRYGG---GGHYEEYRGR 867
Query: 1968 GHSADS-----SRQSGTRHTESSSRGQAASSHEQARSSAGERHGSHHQLQSADSSRHSGI 2022
H S SG +TE+ SRG+ + S+ RS R G + + Q + + G
Sbjct: 868 SHDTHSRGRSPDAHSGDHYTEAYSRGRDSFSNSYGRSDHYGRGGCYEEYQGRSPNAYGGG 927
Query: 2023 GHGQASSAVRDSGHRGYSGSQASDSEGHSEDSDTQSVSAQGKAGPHQQSHKESAR-GQSG 2081
+S+ HR G + + G S D+ + G +S+ S R G G
Sbjct: 928 RGLNSSNNSHGRSHRYGGGGRYEEYRGPSPDAHS------GGRDSSIKSYGLSDRYGGGG 981
Query: 2082 ESSGRSGSFLYQVS-THEQSESTHGQSAPSTGGR-QGSHYDQAQDSSRHSASQEGQDTI- 2138
GS S H++S +++G+S + GR + D+ + S D+
Sbjct: 982 HYEEYQGSLPDAYSGDHDRSSNSYGRSDRYSRGRDRVGRPDRGLPLPMETGSPPLHDSYS 1041
Query: 2139 -RGHPGPSRGGRQGSHQEQSVDRS 2161
G P GGRQG E+ RS
Sbjct: 1042 RSGCRVPRGGGRQGGRFERGEGRS 1065
Score = 133 bits (335), Expect = 3e-30
Identities = 249/1020 (24%), Positives = 363/1020 (35%), Gaps = 204/1020 (20%)
Query: 2877 QSEGSRRSRRQGSSVSQDSDSEGHSEDSERWSGSASRNHHGSAQEQLRDGS-RHPRSHQE 2935
+S S R+R GSS Q S+G +D ++G + + + R RH S
Sbjct: 104 RSRFSHRTRGGGSS-PQRPPSQGRPDDGRGYAGYFDLWPYRAPMPRKRGPPPRHWASPPH 162
Query: 2936 DRAGHGHSADSSRQSGTRHTQTSSGGQAASSHEQARSSAGERHGSHHQQSADSSRHSGIG 2995
RA A S G R + GQ S Q R AG H +++ S + IG
Sbjct: 163 KRATPSSLAHSVG-CGMRGKAPTVSGQDGYSGLQPRRWAGPPH----KRAVPRSSLARIG 217
Query: 2996 -HGQASSAVRDSGHRGYSGSQASDN---------------------EGHSEDSDTQSVSA 3033
G A G GYSG + + GHS D + +
Sbjct: 218 GSGMPGKAPAVWGQDGYSGPRVREPLPPCRDPGDFVPALRDYSRRYYGHSSVPDYRPLRG 277
Query: 3034 HGQAGSHQQSHQESARGRSGETSGHSGSFLYQVSTHEQSESSHG-------WTGPSTRGR 3086
G +Q RGR E + H Y+ E +S G W P + G
Sbjct: 278 DG--------NQNGYRGRDHEYTDHPSKGSYR----EPLKSYGGPCGAAPVWGTPPSYGG 325
Query: 3087 QGSRHEQAQDSSRHSASQ--------------YGQD------------TIRGHPGSSRGG 3120
G R+E+ Q +S + S+ Y +D + G+ S R G
Sbjct: 326 -GCRYEEYQGNSPDACSEGRSSEALPVVLPDAYSRDHSPKAYSGGRSSSSNGYSRSDRYG 384
Query: 3121 RQGYHHEHSVDS-SGHSGSHHSHTTSQGRSDASRGQSGSRSASRTTRNEEQSGDSSRHSV 3179
+G + E+ S HSG +S + S G+S G+ G R +E +SG S +
Sbjct: 385 EEGCYEEYRGRSPDAHSGGRNSSSNSYGQSHHYGGE-GRYEEYRGRSHEARSGGRSTDAH 443
Query: 3180 SRHHEASTHA---DISRHSQAVQGQSEGSRRSRRQGSSVSQDSDSEGHSEDSERWSGSAS 3236
SR ++ D S S G G R QG S+ D++S G S E +SG
Sbjct: 444 SRGRSDDAYSGGHDSSSWSDCCGG---GGRYEEYQGRSL--DANSGGCSP--EAYSGGHD 496
Query: 3237 RNHRGSVQEQSRHGSRHPRSHHEDRAGHGHSADRSRQSGTRHAETSSGGQAASSHEQARS 3296
+ R+G H+E+ GH A+ SG R +T SGG ++SS+ +S
Sbjct: 497 NS-----SWSDRYGVG---GHYEENRGHSLDAN----SGGRSPDTHSGGHSSSSNSYGQS 544
Query: 3297 SPGERHGSRHQQSADSSRHSGIPRGQASSAVRDS----RHWGSSG--------SQASDSE 3344
G + HSG A S DS +G G S ++S
Sbjct: 545 HRYGGEGRYEYRGRSHDAHSGGCSADAYSGGHDSSSQSNRYGGGGCYEEYRGRSLDANSG 604
Query: 3345 GHSEES-----DTQSVSG-HGQAGPHQQSHQESARDRSGGRSGRSGSFLYQVSTHEQSES 3398
G S + D+ S S +G G +++ S SGGRS + S + S
Sbjct: 605 GRSPNAYSGGHDSSSWSHRYGGGGRYEEYRGRSLDANSGGRSPDAYSGGHDSSGQSNCYG 664
Query: 3399 AHGRTRTSTGR--------RQGSHHEQARDSSRHSASQEGQDTIRGHPGSSRRGRQGSHY 3450
GR GR R + DSS S G + G S G
Sbjct: 665 GGGRYEEYRGRLLDANSGGRSPDAYSGGHDSSSQSNRYGGGGRYEEYRGHSLDANSGGRS 724
Query: 3451 EQSVDRSGHSGSHHSHTTSQGRS----------DASRGQSGSRSAS------------RQ 3488
+ R S S H GRS DA G S S S R
Sbjct: 725 PDTYSRGHDSSSQSDHYGGGGRSLDANSSGRLPDAYSGGHDSSSRSHRYGGGGRYEEYRG 784
Query: 3489 TRNDEQSGDGSRHSWSHHHEASTQADSSRHSQSGQGQSAGPRTSRNQGSSVSQDSDSQGH 3548
D SG S +++S H +S++ D R G R N+G S+ D++S GH
Sbjct: 785 RSLDANSGGRSPNAYSGGHNSSSRNDPCR---------GGGRYEENRGHSL--DANSGGH 833
Query: 3549 SEDSERWSGSASRNHRGSAQEQSRDGSRHPTSHHEDRAGHGHSAES-----SRQSGTHHA 3603
S ++ +S N + G H+E+ G H S SG H+
Sbjct: 834 SPNAYSGGRDSSSNSYDRSHRYGGGG------HYEEYRGRSHDTHSRGRSPDAHSGDHYT 887
Query: 3604 ENSSGGQAASSHEQARSSAGERHGSHHQQSADSSRHSGIGHG-QASSAVRDSGHRGSSGS 3662
E S G+ + S+ RS R G + + S G G G +S+ HR G
Sbjct: 888 EAYSRGRDSFSNSYGRSDHYGRGGCYEEYQGRSPNAYGGGRGLNSSNNSHGRSHRYGGGG 947
Query: 3663 QASDSEGHSEDSDT----QSVSAHGQA-----GPHQQSHQEST-------RGRSAGRSGR 3706
+ + G S D+ + S+ ++G + G H + +Q S RS+ GR
Sbjct: 948 RYEEYRGPSPDAHSGGRDSSIKSYGLSDRYGGGGHYEEYQGSLPDAYSGDHDRSSNSYGR 1007
Query: 3707 SGSF---------------LYQVSTHEQSESAHGRAG---PSTGGRQGSRHEQARDSSRH 3748
S + L + ++ R+G P GGRQG R E+ SR+
Sbjct: 1008 SDRYSRGRDRVGRPDRGLPLPMETGSPPLHDSYSRSGCRVPRGGGRQGGRFERGEGRSRY 1067
Score = 130 bits (327), Expect = 3e-29
Identities = 213/891 (23%), Positives = 331/891 (37%), Gaps = 129/891 (14%)
Query: 954 GHSE--DSERWSGSASRN-HRGSAQEQSRHGSRHPRSHHEDRAGHGHSADSSRQSGTPHA 1010
GHS D G ++N +RG E + H S+ S+ E +G ++ GTP
Sbjct: 265 GHSSVPDYRPLRGDGNQNGYRGRDHEYTDHPSKG--SYREPLKSYGGPCGAAPVWGTP-- 320
Query: 1011 ETSSGGQAASSHEQARSSPGERHGSRHQQSADSSRHSGIPRRQASSAVRDSGHWGSSGSQ 1070
S G E +SP R ++ +P + RD SG +
Sbjct: 321 --PSYGGGCRYEEYQGNSPDACSEGRSSEA--------LPVVLPDAYSRDHSPKAYSGGR 370
Query: 1071 ASDSEGHSEESDTQSVSGHGQDGPHQQSHQESARDWSGGRSGRSGSF--IYQVSTHEQSE 1128
+S S G+S +G++G +++ S SGGR+ S S+ + + E
Sbjct: 371 SSSSNGYSRSDR------YGEEGCYEEYRGRSPDAHSGGRNSSSNSYGQSHHYGGEGRYE 424
Query: 1129 SAHGRTRTS-TGRRQGSHHEQARDSSRHSASQEGQDTIRAHPGSRRGGRQGSHHEQSVDR 1187
GR+ + +G R H + R +S + G GGR + +S+D
Sbjct: 425 EYRGRSHEARSGGRSTDAHSRGRSDDAYSGGHDSSSWSDCCGG---GGRYEEYQGRSLDA 481
Query: 1188 SGHSGSHHSHTTSQGRSDAS--HGQSGSRSASRQTRKDKQSGDGS--RHSGSRHHEAASW 1243
+ S +++ S S +G G +R D SG S HSG + S+
Sbjct: 482 NSGGCSPEAYSGGHDNSSWSDRYGVGGHYEENRGHSLDANSGGRSPDTHSGGHSSSSNSY 541
Query: 1244 ADSSRHSQVGQEQSSGSRTSRHQGSSVSQDSDSERH--SDDSERLSGSASRNHHGSSREQ 1301
S R+ G+ + G H G S D+ S H S S R G +
Sbjct: 542 GQSHRYGGEGRYEYRGRSHDAHSGGC-SADAYSGGHDSSSQSNRYGGGGCYEEYRGRSLD 600
Query: 1302 SRDGSRHPGFHQEDRASHGHSADSSRQSGTHHTESSSHGQAVSSHEQARSSPGERHGSRH 1361
+ G R P + H S+ S R G E G+++ ++ RS + + H
Sbjct: 601 ANSGGRSPNAYS---GGHDSSSWSHRYGGGGRYEEY-RGRSLDANSGGRSP--DAYSGGH 654
Query: 1362 QQSADSSRHSGIG-HRQASSAVRDSGHRGSSGSQVTNSEGHSEDSDTQSVSAHGQAGPHQ 1420
S S+ + G G + + + D+ G S S GH DS +QS + +G G ++
Sbjct: 655 DSSGQSNCYGGGGRYEEYRGRLLDANSGGRSPDAY--SGGH--DSSSQS-NRYGGGGRYE 709
Query: 1421 QSHKESARGQSGESSGRSRSFLYQVSSHEQSESTHGQTAPSTGGRQGSRHEQARNSSRHS 1480
+ S SG GRS Y S+S H GG G R A +S R
Sbjct: 710 EYRGHSLDANSG---GRSPD-TYSRGHDSSSQSDH------YGG--GGRSLDANSSGRLP 757
Query: 1481 ASQDGQDTIRGHPGSSR------GGRQGSYHEQSVDRSG-------HSGYHHSHTTPQ-- 1525
+ G GH SSR GGR Y +S+D + +SG H+S +
Sbjct: 758 DAYSG-----GHDSSSRSHRYGGGGRYEEYRGRSLDANSGGRSPNAYSGGHNSSSRNDPC 812
Query: 1526 ---GRSDASHGQSGPRSASRQTRNEEQSGDGSRHSGSRHHEPSTRAGSSRHSQVGQGESA 1582
GR + + G S ++ + N + G R S S ++ S R G H + +G S
Sbjct: 813 RGGGRYEENRGHSLDANSGGHSPN---AYSGGRDSSSNSYDRSHRYGGGGHYEEYRGRSH 869
Query: 1583 GSKTSRRQGSSVSQDRDSEGHSEDSERRSESASRN-HYGSAREQSRHGSRNPRSHQEDRA 1641
+ + R + S D +E +S + S S R+ HYG + R+P ++
Sbjct: 870 DTHSRGRSPDAHSGDHYTEAYSRGRDSFSNSYGRSDHYGRGGCYEEYQGRSPNAY----- 924
Query: 1642 SHGHSAESSRQSGTRHAETSSGGQAASSQEQARSSPGERHGSRHQQSADSSTDSGTGRRQ 1701
G SS S R GG R+++ S D+ +G R
Sbjct: 925 GGGRGLNSSNNSHGRSHRYGGGG-------------------RYEEYRGPSPDAHSGGRD 965
Query: 1702 DSSVVGDSGNRGSSGSQASDSEGHSEESDTQSVSAHGQAGPHQQSHQESTRG----QSGE 1757
S +R G GH EE A+ +G H +S R + +
Sbjct: 966 SSIKSYGLSDRYGGG-------GHYEEYQGSLPDAY--SGDHDRSSNSYGRSDRYSRGRD 1016
Query: 1758 RSGRS--GSFLYQVSTHEQSESAHGRTG---PSTGGRQRSRHEQARDSSRH 1803
R GR G L + ++ R+G P GGRQ R E+ SR+
Sbjct: 1017 RVGRPDRGLPLPMETGSPPLHDSYSRSGCRVPRGGGRQGGRFERGEGRSRY 1067
Score = 129 bits (324), Expect = 6e-29
Identities = 236/983 (24%), Positives = 334/983 (33%), Gaps = 156/983 (15%)
Query: 1674 RSSPGERHGSR--HQQSADSSTDSGTGRRQDSSVVGDSGNRGSSGSQASDSEG--HSEES 1729
+ P RH + H+++ SS G SG G SG Q G H
Sbjct: 149 KRGPPPRHWASPPHKRATPSSLAHSVGCGMRGKAPTVSGQDGYSGLQPRRWAGPPHKRAV 208
Query: 1730 DTQSVSAHGQAG-PHQQSHQESTRGQSGERSGRS-------GSFLYQVSTHEQSESAHGR 1781
S++ G +G P + G SG R G F+ + + + H
Sbjct: 209 PRSSLARIGGSGMPGKAPAVWGQDGYSGPRVREPLPPCRDPGDFVPALRDYSRRYYGHSS 268
Query: 1782 T---------GPSTGGRQRSRHEQARDSSRHSASQE--------GQDTIRGHPGSSRGGR 1824
G G R R HE S+ S + G + G P S GG
Sbjct: 269 VPDYRPLRGDGNQNGYRGRD-HEYTDHPSKGSYREPLKSYGGPCGAAPVWGTPPSYGGGC 327
Query: 1825 QGSHYEQS----------------VDSSGHSGSHHSHTTSQERSDVSRGQSGSRSVSRQT 1868
+ Y+ + V +S H S RS S G S S +
Sbjct: 328 RYEEYQGNSPDACSEGRSSEALPVVLPDAYSRDHSPKAYSGGRSSSSNGYSRSDRYGEEG 387
Query: 1869 RNEKQSGDG-SRHSGSRHHEASSRADSSRHSQVGQGQSSGPRTSRNQGSSVSQDSDSQGH 1927
E+ G HSG R+ ++S S + G+ + R+ + S D+ S+G
Sbjct: 388 CYEEYRGRSPDAHSGGRNSSSNSYGQSHHYGGEGRYEEYRGRSHEARSGGRSTDAHSRGR 447
Query: 1928 SEDSERWSGSASRNHLGSAWEQSRDGSRHPGSHHEDRAGHGHSADSSRQSGTRHTESSSR 1987
S+D+ +SG H S+W G G +E+ G A+S G E+ S
Sbjct: 448 SDDA--YSGG----HDSSSWSDCCGG----GGRYEEYQGRSLDANS----GGCSPEAYSG 493
Query: 1988 GQAASSHEQARSSAGERHGSH-HQLQSADSSR----HSGIGHGQASSAVRDSGHRGYSGS 2042
G SS G + H L + R HSG GH +S++ S HR Y G
Sbjct: 494 GHDNSSWSDRYGVGGHYEENRGHSLDANSGGRSPDTHSG-GHSSSSNSYGQS-HR-YGGE 550
Query: 2043 QASDSEGHSEDSDTQSVSAQGKAGPHQQSHKESARGQSG---ESSGRSGSFLYQVSTHEQ 2099
+ G S D+ + SA +G H S + + G G E GRS
Sbjct: 551 GRYEYRGRSHDAHSGGCSADAYSGGHDSSSQSNRYGGGGCYEEYRGRSLD---------- 600
Query: 2100 SESTHGQSAPSTGGRQGSHYDQAQDSSRHSASQEGQDTIRGHPGPSRGGRQGSHQEQSVD 2159
++GGR + Y DSS S G + G S G +
Sbjct: 601 ---------ANSGGRSPNAYSGGHDSSSWSHRYGGGGRYEEYRGRSLDANSGGRSPDAYS 651
Query: 2160 RSGHSGSHHSHT-TSQGRSDASRGQ-----SGSRSASRKTYDKEQSGDGSRHSGSHHHEA 2213
GH S S+ GR + RG+ SG RS + + S +R+ G +E
Sbjct: 652 -GGHDSSGQSNCYGGGGRYEEYRGRLLDANSGGRSPDAYSGGHDSSSQSNRYGGGGRYE- 709
Query: 2214 SSWADSSRHSLVGQGQSSGPRT-SRPRGSSVSQDSDSEGHSEDSERRSGSASRNHHGSAQ 2272
+ HSL P T SR SS D G SG + G
Sbjct: 710 ----EYRGHSLDANSGGRSPDTYSRGHDSSSQSDHYGGGGRSLDANSSGRLPDAYSGGHD 765
Query: 2273 EQSRDGSRHPRSHHEDRAGHGHSAESSRQSGTHHAENSSGGQAASSHEQARSSAGERHGS 2332
SR +E+ G A S +S + S G ++S ++ R
Sbjct: 766 SSSRSHRYGGGGRYEEYRGRSLDANSGGRSPNAY---SGGHNSSSRNDPCRGGGRYEENR 822
Query: 2333 HHQQSADSSRHSG---IGHGQASSAVRDSGHRGSSGSQASDSEGHSEDSDTQSVSAHGQA 2389
H A+S HS G +SS D HR G + G S D+ ++ S +
Sbjct: 823 GHSLDANSGGHSPNAYSGGRDSSSNSYDRSHRYGGGGHYEEYRGRSHDTHSRGRSPDAHS 882
Query: 2390 GPHQQSHQESTRGR-----SAGRS---GRSGSFLYQVSTHEQSESAHGRTGTSTGGRQG- 2440
G H + +RGR S GRS GR G + E GR+ + GG +G
Sbjct: 883 GDHYT--EAYSRGRDSFSNSYGRSDHYGRGGCY----------EEYQGRSPNAYGGGRGL 930
Query: 2441 -SHHKQARDSSRHSTSQEGQDTIHGHPGSSSGGRQ--------------GSHYEQLVDR- 2484
S + S R+ ++ P + SGGR G HYE+
Sbjct: 931 NSSNNSHGRSHRYGGGGRYEEYRGPSPDAHSGGRDSSIKSYGLSDRYGGGGHYEEYQGSL 990
Query: 2485 -SGHSGSHHSHTTSQGRSDASHGHSGSRSASRQTRNDEQSGDGSRHSGSRHHEASSRADS 2543
+SG H + S GRSD SR R R D H++ SR
Sbjct: 991 PDAYSGDHDRSSNSYGRSDRY-----SRGRDRVGRPDRGLPLPMETGSPPLHDSYSR--- 1042
Query: 2544 SGHSQVGQGQSEGPRTSRNWGSS 2566
SG G +G R R G S
Sbjct: 1043 SGCRVPRGGGRQGGRFERGEGRS 1065
Score = 126 bits (317), Expect = 4e-28
Identities = 219/962 (22%), Positives = 322/962 (33%), Gaps = 143/962 (14%)
Query: 2982 HQQSADSSRHSGIGHGQASSAVRDSGHRGYSGSQASDNEGHSEDSDTQSVSAHGQAGSHQ 3041
H+++ SS +G G A SG GYSG Q G H +A
Sbjct: 162 HKRATPSSLAHSVGCGMRGKAPTVSGQDGYSGLQPRRWAG----------PPHKRAVPRS 211
Query: 3042 QSHQESARGRSGETSGHSGSFLYQVSTHEQSESSHGWTGPSTRGR------QGSRHEQAQ 3095
+ G G+ G G++GP R G +
Sbjct: 212 SLARIGGSGMPGKAPAVWGQ--------------DGYSGPRVREPLPPCRDPGDFVPALR 257
Query: 3096 DSSRHSASQYGQDTIRGH-PGSSRGGRQGYH-HEHSVDSSGHSGSHHSHTTSQGRSDASR 3153
D SR YG ++ + P G + GY +H GS+ S G +
Sbjct: 258 DYSRR---YYGHSSVPDYRPLRGDGNQNGYRGRDHEYTDHPSKGSYREPLKSYGGPCGAA 314
Query: 3154 GQSGSR-SASRTTRNEEQSGDSSRHSVSRHHEASTHADISRHSQAVQGQSEGSRRSRRQG 3212
G+ S R EE G+S SEG RS
Sbjct: 315 PVWGTPPSYGGGCRYEEYQGNSP-----------------------DACSEG--RSSEAL 349
Query: 3213 SSVSQDSDSEGHSEDSERWSGSASRNHRGSVQEQSRHGSRHPRSHHEDRAGHGHSADRSR 3272
V D+ S HS + +SG S + G R+G + R+ HS
Sbjct: 350 PVVLPDAYSRDHSPKA--YSGGRSSSSNG-YSRSDRYGEEGCYEEYRGRSPDAHS----- 401
Query: 3273 QSGTRHAETSSGGQAASSHEQARSSPGERHGSRHQQSADSSRHSGIPRGQASSAVRDSRH 3332
G R++ ++S GQ S H E G H+ + RG++ A H
Sbjct: 402 --GGRNSSSNSYGQ--SHHYGGEGRYEEYRGRSHEARSGGRSTDAHSRGRSDDAYSGG-H 456
Query: 3333 WGSSGSQASDSEGHSEESDTQSVSGH-GQAGPHQQSHQESARDRSGGRSGRSGSFLYQVS 3391
SS S G EE +S+ + G P S GG S S Y V
Sbjct: 457 DSSSWSDCCGGGGRYEEYQGRSLDANSGGCSPEAYS---------GGHDNSSWSDRYGVG 507
Query: 3392 THEQSESAHGRTRTSTGRRQGSHHEQARDSSRHSASQEGQDTIRGHPGSSR---RGRQGS 3448
H + H S GR +H S HS+S + G R RGR
Sbjct: 508 GHYEENRGHSLDANSGGRSPDTH------SGGHSSSSNSYGQSHRYGGEGRYEYRGRSHD 561
Query: 3449 HYEQSVDRSGHSGSHHSHTTSQGRSDASRGQSGSRSASRQTRNDEQSGDGSRHSWSHHHE 3508
+ +SG H S + S G G R D SG S +++S H+
Sbjct: 562 AHSGGCSADAYSGGHDSSSQSN-----RYGGGGCYEEYRGRSLDANSGGRSPNAYSGGHD 616
Query: 3509 ASTQADSSRHSQSGQGQSAGPRTSRNQGSSVSQDSDSQGHSEDSER---WSGSASRNHRG 3565
+S+ S R+ G+ + R+ S D+ S GH + G +RG
Sbjct: 617 SSSW--SHRYGGGGRYEEYRGRSLDANSGGRSPDAYSGGHDSSGQSNCYGGGGRYEEYRG 674
Query: 3566 SAQEQSRDGSRHPTSHHEDRAGHGHSAESSRQSGTHHAENSSGGQAASSHEQARSSAGER 3625
+ + G R P ++ GH S++S+R G E G H +S G
Sbjct: 675 RLLD-ANSGGRSPDAYS---GGHDSSSQSNRYGGGGRYEEYRG------HSLDANSGGRS 724
Query: 3626 HGSHHQQSADSSRHSGIGHGQASSAVRDSGHRGSSGSQASDSEGHSEDSDTQSVSAHGQA 3685
++ + SS+ G G S SG + S DS S +G
Sbjct: 725 PDTYSRGHDSSSQSDHYGGGGRSLDANSSGRLPDAYSGGHDSSSRSH--------RYGGG 776
Query: 3686 GPHQQSHQESTRGRSAGRSGRSGSFLYQVSTHEQSESAHGR--------AGPSTGGRQGS 3737
G +++ S S GRS + S + S+ GR ++GG +
Sbjct: 777 GRYEEYRGRSLDANSGGRSPNAYSGGHNSSSRNDPCRGGGRYEENRGHSLDANSGGHSPN 836
Query: 3738 RHEQARDSSRHSASQEGQDTIRGHPGSRRGGRQGSYHEQSVDRSGHSGSHHSHTTSQGRS 3797
+ RDSS +S + + GH RG R H + HSG H++ S+GR
Sbjct: 837 AYSGGRDSSSNSYDRSHRYGGGGHYEEYRG-RSHDTHSRGRSPDAHSGDHYTEAYSRGRD 895
Query: 3798 DASHGQSGSRSASRETRNEEQSG-DGSRHSGSRHHEASTQADSSRHSQSGQGESAGSRRS 3856
S+ S R EE G + + G R +S + H G G R
Sbjct: 896 SFSNSYGRSDHYGRGGCYEEYQGRSPNAYGGGRGLNSSNNSHGRSHRYGG-----GGRYE 950
Query: 3857 RRQGSSVSQDSDSEAYPEDSERRSESASRNHHGSSREQSRDGS---RHPGSSHRDTASHV 3913
+G S D+ + DS +S S + G + GS + G R + S+
Sbjct: 951 EYRGPS----PDAHSGGRDSSIKSYGLSDRYGGGGHYEEYQGSLPDAYSGDHDRSSNSYG 1006
Query: 3914 QS 3915
+S
Sbjct: 1007 RS 1008
Score = 126 bits (316), Expect = 5e-28
Identities = 173/754 (22%), Positives = 270/754 (35%), Gaps = 80/754 (10%)
Query: 329 SRDGSRHPRSHDEDRASHGHSADSSRQSGTRHAETSSRGQTASSHEQARSSPGERHGSGH 388
SRD S P+++ R+S + S + G RG++ +H R+S +G H
Sbjct: 358 SRDHS--PKAYSGGRSSSSNGYSRSDRYGEEGCYEEYRGRSPDAHSGGRNSSSNSYGQSH 415
Query: 389 QQSADSSRHSATGRG-QASSAVSDRGHRGSSGSQASDSEGHSENSDTQSVSGHGK----- 442
+ GR +A S S + S GH +S + G G+
Sbjct: 416 HYGGEGRYEEYRGRSHEARSGGRSTDAHSRGRSDDAYSGGHDSSSWSDCCGGGGRYEEYQ 475
Query: 443 -AGLRQQSHQESTRGRSGERSGRSGSSLYQVSTHEQPDSAHGRTGTSTGGRQGSHHEQAR 501
L S S SG S S Y V H + + H S GGR H
Sbjct: 476 GRSLDANSGGCSPEAYSGGHDNSSWSDRYGVGGHYEENRGHSLDANS-GGRSPDTHSGGH 534
Query: 502 DSSRHSASQEGQDTIRGHPGSSRGGRQGSHHEQSVNRSGHSGSHHSHTTSQGRSDAS--- 558
SS +S Q S R G +G + + + HSG + S G +S
Sbjct: 535 SSSSNSYGQ-----------SHRYGGEGRYEYRGRSHDAHSGGCSADAYSGGHDSSSQSN 583
Query: 559 -HGQSGSRSASRQTRNEEQSGDGTRHSGSRHHEASSQADSSRHSQVGQGQSSGPRTSRNQ 617
+G G R + SG + ++ S H++SS S R+ G+ + R+
Sbjct: 584 RYGGGGCYEEYRGRSLDANSGGRSPNAYSGGHDSSSW--SHRYGGGGRYEEYRGRSLDAN 641
Query: 618 GSSVSQDSDSQGH--SEDSERWSGSASRNHHGSAQEQSRDGSRHPRSHHEDRAGHGHSAD 675
S D+ S GH S S + G + + G R P ++ GH S+
Sbjct: 642 SGGRSPDAYSGGHDSSGQSNCYGGGGRYEEYRGRLLDANSGGRSPDAY---SGGHDSSSQ 698
Query: 676 SSRKSG-------TRHTQNSSSGQAAS---SHEQARSSAGERHGSRHQLQSADSS----- 720
S+R G H+ +++SG + S SS + +G + A+SS
Sbjct: 699 SNRYGGGGRYEEYRGHSLDANSGGRSPDTYSRGHDSSSQSDHYGGGGRSLDANSSGRLPD 758
Query: 721 RHSGTGHGQASSAVRDSGHRGSSGSQATDSEGHSEDSDTQSVSGHGQAGHHQQSHQESAR 780
+SG GH +S + HR G + + G S D+++ S + +G H S +
Sbjct: 759 AYSG-GHDSSSRS-----HRYGGGGRYEEYRGRSLDANSGGRSPNAYSGGHNSSSRNDPC 812
Query: 781 DRSGERSRRSGSFLYQVSTHKQSESSHGWTGPSTGVRQGSHHEQARDNSRHSASQDGQDT 840
G G + + + S + ++G RD+S +S + +
Sbjct: 813 RGGGRYEENRG---HSLDANSGGHSPNAYSG-------------GRDSSSNSYDRSHRYG 856
Query: 841 IRGHPGSSRRGRQGSHHEQSVDRSGHSGSHHSHTTSQGRSDASRGQSGSRSASRTTRNEE 900
GH RGR H + HSG H++ S+GR S S R EE
Sbjct: 857 GGGH-YEEYRGRSHDTHSRGRSPDAHSGDHYTEAYSRGRDSFSNSYGRSDHYGRGGCYEE 915
Query: 901 -QSRDGSRHSGSRHHEASSHADISRHSQAGQGQSEGSRTSRRQGSSVSQDSDSEGHSEDS 959
Q R + + G R +S+++ H G G+ E R S +DS + +
Sbjct: 916 YQGRSPNAYGGGRGLNSSNNSHGRSHRYGGGGRYEEYRGPSPDAHSGGRDSSIKSYGLSD 975
Query: 960 ERWSGSASRNHRGSAQEQSRHGSRHPRSHH----EDRAGHGHSADSSRQSGTP-HAETSS 1014
G ++GS + + H RS + DR G G P ET S
Sbjct: 976 RYGGGGHYEEYQGSLPD--AYSGDHDRSSNSYGRSDRYSRGRDRVGRPDRGLPLPMETGS 1033
Query: 1015 GGQAASSHEQARSSP--GERHGSRHQQSADSSRH 1046
S P G R G R ++ SR+
Sbjct: 1034 PPLHDSYSRSGCRVPRGGGRQGGRFERGEGRSRY 1067
Score = 112 bits (280), Expect = 7e-24
Identities = 155/684 (22%), Positives = 250/684 (36%), Gaps = 67/684 (9%)
Query: 140 RSKSPRETGGKRHESSSEKKERKGYSPTHREEEYGKNHHNSSKKEKNKTENTRLGDNRKR 199
R SP+ G R SS+ Y EEY ++ +N + N+ +
Sbjct: 359 RDHSPKAYSGGRSSSSNGYSRSDRYGEEGCYEEYRGRSPDAHSGGRNSSSNSYGQSHHYG 418
Query: 200 LSERLEEKEDNEEGVYDYENTGRMTQKWIQSGHIATYYTIQDEAYDTTDSLLEENKIYE- 258
R EE ++ + GR T G Y+ ++ +D + E
Sbjct: 419 GEGRYEEYRGRS---HEARSGGRSTDAH-SRGRSDDAYSGGHDSSSWSDCCGGGGRYEEY 474
Query: 259 RSRSSDGKS---SSQVNRSRHENTSQVPLQESRTRKRRGSRVSQDRDSEGHSEDSERHSG 315
+ RS D S S + H+N+S S D +S G S D+
Sbjct: 475 QGRSLDANSGGCSPEAYSGGHDNSSWSDRYGVGGHYEENRGHSLDANSGGRSPDTHSGGH 534
Query: 316 SASRNHHGSAWEQSRDGSRHPRSHDEDRASHGHSADSSRQSGTRHAETSSRGQTASSHEQ 375
S+S N +G + +G R D S G SAD + G + S+R +E+
Sbjct: 535 SSSSNSYGQSHRYGGEGRYEYRGRSHDAHSGGCSAD-AYSGGHDSSSQSNRYGGGGCYEE 593
Query: 376 ARSSPGERHGSGHQQSADSSRHSATGRGQASSAVSDRGHRGSSGSQASDSEGHSENSDTQ 435
R + + G +A S H + S HR G + + G S ++++
Sbjct: 594 YRGRSLDANSGGRSPNAYSGGHDS----------SSWSHRYGGGGRYEEYRGRSLDANSG 643
Query: 436 SVSGHGKAGLRQQSHQESTRGRSGERSGRSGSSLYQVSTHEQPDSAHGRTGTSTGGRQ-- 493
S +G S Q + G G G L S PD+ G +S+ +
Sbjct: 644 GRSPDAYSGGHDSSGQSNCYGGGGRYEEYRGRLLDANSGGRSPDAYSGGHDSSSQSNRYG 703
Query: 494 -GSHHEQARDSS--RHSASQEGQDTIRGHPGSSR------GGRQGSHHEQSVNRSGHSGS 544
G +E+ R S +S + RGH SS+ GGR + +SG
Sbjct: 704 GGGRYEEYRGHSLDANSGGRSPDTYSRGHDSSSQSDHYGGGGRSLDANSSGRLPDAYSGG 763
Query: 545 HHSHTTSQGRSDASHGQSGSRSASRQTRNEEQSGDGTRHSGSRHHEASSQADSSRHSQVG 604
H S + S +G G R + SG + ++ S H +SS+ D R
Sbjct: 764 HDSSSRSH-----RYGGGGRYEEYRGRSLDANSGGRSPNAYSGGHNSSSRNDPCR----- 813
Query: 605 QGQSSGPRTSRNQGSSVSQDSDSQGHSEDSERWSGSASRNHHGSAQEQSRDGSRHPRSHH 664
G R N+G S+ D++S GHS ++ +S N + + G H+
Sbjct: 814 ----GGGRYEENRGHSL--DANSGGHSPNAYSGGRDSSSNSYDRSHRYGGGG------HY 861
Query: 665 EDRAGHGHSADSSRK-----SGTRHTQNSSSGQAASSHEQARSSAGERHGSRHQLQSADS 719
E+ G H S + SG +T+ S G+ + S+ RS R G + Q
Sbjct: 862 EEYRGRSHDTHSRGRSPDAHSGDHYTEAYSRGRDSFSNSYGRSDHYGRGGCYEEYQGRSP 921
Query: 720 SRHSGTGHGQASSAVRDSGHRGSSGSQATDSEGHSEDSDT----QSVSGHGQA-----GH 770
+ + G +S+ HR G + + G S D+ + S+ +G + G
Sbjct: 922 NAYGGGRGLNSSNNSHGRSHRYGGGGRYEEYRGPSPDAHSGGRDSSIKSYGLSDRYGGGG 981
Query: 771 HQQSHQESARDR-SGERSRRSGSF 793
H + +Q S D SG+ R S S+
Sbjct: 982 HYEEYQGSLPDAYSGDHDRSSNSY 1005
Score = 78.6 bits (192), Expect = 1e-13
Identities = 170/720 (23%), Positives = 241/720 (33%), Gaps = 130/720 (18%)
Query: 3331 RHWGS------SGSQASDSEGHSEESDTQSVSGH-GQAG---------PHQQSHQESARD 3374
RHW S + S + S G +VSG G +G PH+++ S+
Sbjct: 155 RHWASPPHKRATPSSLAHSVGCGMRGKAPTVSGQDGYSGLQPRRWAGPPHKRAVPRSSLA 214
Query: 3375 RSGGRSGRSGSFLYQVSTHEQSESAHGRTRTSTGRRQGSHHEQARDSSRHSASQEGQDTI 3434
R GG SG G V + R R G RD SR
Sbjct: 215 RIGG-SGMPGK-APAVWGQDGYSGPRVREPLPPCRDPGDFVPALRDYSRRYYGHSSVPDY 272
Query: 3435 RGHPGSSR----RGR---------QGSHYEQSVDRSGHSGSHHSHTTSQGRSDASRG--- 3478
R G RGR +GS+ E G G+ T R
Sbjct: 273 RPLRGDGNQNGYRGRDHEYTDHPSKGSYREPLKSYGGPCGAAPVWGTPPSYGGGCRYEEY 332
Query: 3479 QSGSRSASRQTRNDEQSGDGSRHSWSHHHEASTQADSSRHSQSGQGQSAGPRTSRNQGSS 3538
Q S A + R+ E ++S H S +A S S S G S R
Sbjct: 333 QGNSPDACSEGRSSEALPVVLPDAYSRDH--SPKAYSGGRSSSSNGYSRSDRYGEE---- 386
Query: 3539 VSQDSDSQGHSEDSERWSGSASRNHRGSAQEQSRDGSRHPTSHHEDRAGHGHSAESSRQS 3598
+ +G S D+ ++S N G + +G +E+ G H A S +S
Sbjct: 387 -GCYEEYRGRSPDAHSGGRNSSSNSYGQSHHYGGEG------RYEEYRGRSHEARSGGRS 439
Query: 3599 GTHHAENSSGGQAASSHEQARSS----AGERHGSHHQQSADSSRHSGIGHGQASSAVRDS 3654
H+ S + H+ + S G R+ + +S D++ G S
Sbjct: 440 TDAHSRGRSDDAYSGGHDSSSWSDCCGGGGRYEEYQGRSLDANS------GGCSPEAYSG 493
Query: 3655 GHRGSSGSQASDSEGHSEDSDTQSVSAH-GQAGPHQQSHQESTRGRSAGRS---GRSGSF 3710
GH SS S GH E++ S+ A+ G P S S+ S G+S G G +
Sbjct: 494 GHDNSSWSDRYGVGGHYEENRGHSLDANSGGRSPDTHSGGHSSSSNSYGQSHRYGGEGRY 553
Query: 3711 LYQVSTHEQSESAHGRAGPSTGGRQGSRHEQARDSSRHSASQEGQDTIRGHPGSRRGGRQ 3770
Y+ +H+ AH +GG + DSS S G GG
Sbjct: 554 EYRGRSHD----AH------SGGCSADAYSGGHDSSSQSNRYGG------------GGCY 591
Query: 3771 GSYHEQSVDRSGHSGSHHSHTTSQGRSDASHGQSGSRSASRETRNEEQSGDG-SRHSGSR 3829
Y +S+D + S ++++ S SH G R EE G +SG R
Sbjct: 592 EEYRGRSLDANSGGRSPNAYSGGHDSSSWSHRYGGGG------RYEEYRGRSLDANSGGR 645
Query: 3830 HHEASTQADSSRHSQSGQGESAGSRRSRRQGSSVSQDSDSEAYPEDSERRSESASRNHHG 3889
S A S H SGQ G G ++ +S RS A H
Sbjct: 646 ----SPDAYSGGHDSSGQSNCYG-------GGGRYEEYRGRLLDANSGGRSPDAYSGGHD 694
Query: 3890 SSREQSRDGSRHPGSSHRDTASHVQSSPVQSDSSTAKEHGHFSSLSQDSAYHS-GIQSRG 3948
SS + +R G G + + H SL +S S SRG
Sbjct: 695 SSSQSNRYGG---GGRYEEYRGH--------------------SLDANSGGRSPDTYSRG 731
Query: 3949 SPHSSSSYHYQSEGTERQKGQSGLVWRHGSYG----SADYDYGESGFRHSQHGSVSYNSN 4004
SS S HY G SG + S G S + YG G R+ ++ S ++N
Sbjct: 732 HDSSSQSDHYGGGGRSLDANSSGRLPDAYSGGHDSSSRSHRYGGGG-RYEEYRGRSLDAN 790
Score = 69.3 bits (168), Expect = 7e-11
Identities = 133/605 (21%), Positives = 196/605 (32%), Gaps = 84/605 (13%)
Query: 88 STRKENLPISGH--KHRKHSHHDKHEDNKQEENKENRKRPSSLERRNNRKGNKGRSKSPR 145
S+ + + GH ++R HS + + S+ +++R G +GR
Sbjct: 498 SSWSDRYGVGGHYEENRGHSLDANSGGRSPDTHSGGHSSSSNSYGQSHRYGGEGRY---- 553
Query: 146 ETGGKRHESSSEKKERKGYSPTHREEEYGKNHHNSSKKEKNKTENTRLGDNRKRLSERLE 205
E G+ H++ S YS H + E+ + + ++ R
Sbjct: 554 EYRGRSHDAHSGGCSADAYSGGHDSSSQSNRYGGGGCYEEYRGRSLD-ANSGGRSPNAYS 612
Query: 206 EKEDNEEGVYDYENTGRMTQKWIQSGHIATYYTIQDEAYDTTDSLLEENKIYERSRSSDG 265
D+ + Y GR Y + + D + Y S G
Sbjct: 613 GGHDSSSWSHRYGGGGR-------------YEEYRGRSLDANSGGRSPDA-YSGGHDSSG 658
Query: 266 KSSSQVNRSRHENTSQVPLQESRTRKRRGSRVSQDRDSEGH--SEDSERHSGSASRNHHG 323
+S+ R+E R S D S GH S S R+ G +
Sbjct: 659 QSNCYGGGGRYEE------YRGRLLDANSGGRSPDAYSGGHDSSSQSNRYGGGGRYEEYR 712
Query: 324 SAWEQSRDGSRHPRSHDEDRASHGHSADSSRQS-----GTRHAETSSRGQTASSHEQAR- 377
+ G R P D S GH DSS QS G R + +S G+ ++
Sbjct: 713 GHSLDANSGGRSP-----DTYSRGH--DSSSQSDHYGGGGRSLDANSSGRLPDAYSGGHD 765
Query: 378 -SSPGERHGSGHQQSADSSRHSATGRGQASSAVSDRGHRGSS-------GSQASDSEGHS 429
SS R+G G + R G S GH SS G + ++ GHS
Sbjct: 766 SSSRSHRYGGGGRYEEYRGRSLDANSGGRSPNAYSGGHNSSSRNDPCRGGGRYEENRGHS 825
Query: 430 ENSDTQSVSGHGKAGLRQQSHQESTRGRSGERSGRSGSSLYQVSTHEQPDSAHGRTGTST 489
++++ S + +G R S S +RS R G + + H R G S
Sbjct: 826 LDANSGGHSPNAYSGGRDSS------SNSYDRSHRYGGGGHYEEYRGRSHDTHSR-GRSP 878
Query: 490 GGRQGSHHEQARDSSRHSASQE-GQDTIRGHPGSSRGGRQGSHHEQSVNRSGHSGSHHSH 548
G H+ +A R S S G+ G RGG + +S N G +S
Sbjct: 879 DAHSGDHYTEAYSRGRDSFSNSYGRSDHYG-----RGGCYEEYQGRSPNAYGGGRGLNSS 933
Query: 549 TTSQGRSDASHGQSGSRSASRQTRNEEQSGDG-TRHSGSRHHEASSQADSSRHSQVGQGQ 607
S GRS +G G R EE G HSG R S S R+ G +
Sbjct: 934 NNSHGRSH-RYGGGG--------RYEEYRGPSPDAHSGGRDSSIKSYGLSDRYGGGGHYE 984
Query: 608 SSGPRTSRNQGSSVSQDSDSQGHSEDSERWSGSASRNHHGSA-----------QEQSRDG 656
+ S+S G S+ R R G SR G
Sbjct: 985 EYQGSLPDAYSGDHDRSSNSYGRSDRYSRGRDRVGRPDRGLPLPMETGSPPLHDSYSRSG 1044
Query: 657 SRHPR 661
R PR
Sbjct: 1045 CRVPR 1049
Score = 33.1 bits (74), Expect = 5.8
Identities = 55/282 (19%), Positives = 90/282 (31%), Gaps = 36/282 (12%)
Query: 86 YESTRKENLPISGHKHRKHSHHDKHEDNKQEENKENRKRPSSLERRNNRKGNKGRSKSPR 145
YE R +L + +++ H + + + R R ++ N G
Sbjct: 779 YEEYRGRSLDANSGGRSPNAYSGGHNSSSRNDPCRGGGRYEE-NRGHSLDANSGGHSPNA 837
Query: 146 ETGGKRHESSSEKKERKGYSPTHREEEYGKNHHNSSKKEKNKTENTRLGDNRKRLSERLE 205
+GG+ S+S + + H EE G++H S + ++ + GD+ R
Sbjct: 838 YSGGRDSSSNSYDRSHRYGGGGHYEEYRGRSHDTHS---RGRSPDAHSGDHYTEAYSRGR 894
Query: 206 EKEDNEEGVYDYENTGRMTQKWIQSGHIATYYTIQDEAYDTTDSLLEENKIYERSRSSDG 265
+ N G D+ G G Y AY L N + RS G
Sbjct: 895 DSFSNSYGRSDHYGRG---------GCYEEYQGRSPNAYGGGRGLNSSNNSHGRSHRYGG 945
Query: 266 KSSSQVNRSRHENTSQVPLQESRTRKRRGSRVSQDRDSEGHSEDSERHSGSASRNHHGSA 325
R + RG S D S G + S + G + R G
Sbjct: 946 --------------------GGRYEEYRGP--SPDAHSGGR-DSSIKSYGLSDRYGGGGH 982
Query: 326 WEQSRDGSRHPRSHDEDRASHGHSADSSRQSGTRHAETSSRG 367
+E+ + S D DR+S+ + G RG
Sbjct: 983 YEEYQGSLPDAYSGDHDRSSNSYGRSDRYSRGRDRVGRPDRG 1024
>gi|148746195 trichohyalin [Homo sapiens]
Length = 1943
Score = 122 bits (305), Expect = 9e-27
Identities = 198/992 (19%), Positives = 327/992 (32%), Gaps = 113/992 (11%)
Query: 1 MSTLLENIFAIINLFKQYSKKDKNTDTLSKKELKELLEKEFRQILKNPDDPDMVDVFMDH 60
MS LL +I I +F QY D + L+KK+LK LLE+EF +L+ P DP VD+ ++
Sbjct: 1 MSPLLRSICDITEIFNQYVSHDCDGAALTKKDLKNLLEREFGAVLRRPHDPKTVDLILEL 60
Query: 61 LDIDHNKKIDFTEFLLMVFKLAQAYYESTRKENLPISGHKHRKHSHHDKHEDNKQEENKE 120
LD+D N ++DF EFLL +FK+AQA Y + + + R +D +QEE++
Sbjct: 61 LDLDSNGRVDFNEFLLFIFKVAQACYYALGQATGLDEEKRARCDGKESLLQDRRQEEDQR 120
Query: 121 N-RKRPSSLERRNNRKGNKGRSKSPRETGGKRHESSSEKKER-KGYSPTHREEEYGKNHH 178
R LE ++ + R + RE E SEK+ER + R+EE +
Sbjct: 121 RFEPRDRQLEEEPGQRRRQKRQEQERELA--EGEEQSEKQERLEQRDRQRRDEELWRQRQ 178
Query: 179 NSSKKEKNKTENTRLGDNRKRLSERLEEKED-NEEGVYDYENTGRMTQKWIQSGHIATYY 237
++E+ + E +L + +E ++E + + GR ++ +
Sbjct: 179 EWQEREERRAEEEQLQSCKGHETEEFPDEEQLRRRELLELRRKGREEKQQQRRER----- 233
Query: 238 TIQDEAYDTTDSLLEENKIYERSRSSDGKSSSQVNRSRHENTSQVPLQESRTRKRRGSRV 297
QD + EE K + + + K ++ + ++ +E + RK +
Sbjct: 234 --QDRVFQE-----EEEKEWRKRETVLRKEEEKLQEEEPQRQRELQEEEEQLRKLERQEL 286
Query: 298 SQDRDSEGHSEDSERHSGSASRNHHGSAWEQSRDGSRHPRSHDEDRASHGHSADSSRQSG 357
++R E + R R E+ R+ R E R Q
Sbjct: 287 RRERQEEEQQQQRLRREQQLRRKQE----EERREQQEERREQQERR----------EQQE 332
Query: 358 TRHAETSSRGQTASSHEQARSSPGERHGSGHQQSADSSRHSATGRGQASSAVSDRGHRGS 417
R + R Q +Q R ++ + R R Q + R
Sbjct: 333 ERREQQLRREQEERREQQLR-----------REQEEERREQQLRREQEEERREQQLRREQ 381
Query: 418 SGSQASDSEGHSENSDTQSVSGHGKAGLRQQSHQESTRGRSGERSGRSGSSLYQVSTHEQ 477
+ + Q + + QQ +E R Q EQ
Sbjct: 382 QLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRRE------------QQLRREQ 429
Query: 478 PDSAHGRTGTSTGGRQGSHHEQARDSSRHSASQEGQDTIRGHPGSSRGGRQGSHHEQSVN 537
+ H + HEQ R R QE + R E+
Sbjct: 430 EEERHEQ-----------KHEQERREQRLKREQEER-------------RDWLKREEETE 465
Query: 538 RSGHSGSHHSHTTSQGRSDASHGQSGSRSASRQTRNEEQSGDGTRHSGSRHHEASSQADS 597
R H + + Q R EE+ R R + +
Sbjct: 466 R---------HEQERRKQQLKRDQEEERRERWLKLEEEE----RREQQERREQQLRREQE 512
Query: 598 SRHSQVGQGQSSGPRTSRNQGSSVSQDSDSQGHSEDSERWSGSASRNHHGSAQEQSRDGS 657
R Q + Q R + S + Q E ER R EQ R
Sbjct: 513 ERREQRLKRQEEEERLQQRLRS------EQQLRREQEERREQLLKREEE-KRLEQERREQ 565
Query: 658 RHPRSHHEDRAGHGHSADSSRKSGTRHTQNSSSGQAASSHEQARSSAGERHGSRHQLQSA 717
R R E R + R+ + Q Q E R ER R + +
Sbjct: 566 RLKREQEERRDQLLKREEERRQQRLKREQEERLEQRLKREEVERLEQEERREQRLKREEP 625
Query: 718 DSSRHSGTGHGQASSAVRDSGHRGSSGSQATDSEGHSEDSD--TQSVSGHGQAGHHQQSH 775
+ R + R R + E+ + Q + + +Q
Sbjct: 626 EEERRQQLLKSEEQEERRQQQLRREQQERREQRLKREEEEERLEQRLKREHEEERREQEL 685
Query: 776 QESARDRSGERSR-RSGSFLYQVSTHKQSESSHGWTGPSTGVRQGSHHEQARDNSRHSAS 834
E ++++ ER + R + +Q+ + + S ++ P Q EQ R +
Sbjct: 686 AEEEQEQARERIKSRIPKWQWQLESEADARQSKVYSRPRKQEGQRRRQEQEEKRRRRESE 745
Query: 835 QDGQDTIRGHPGSSRRGRQGSHHEQSVDRSGHSGSHHSHTTSQGRSDASRGQSGSRSASR 894
Q+ R H RQ EQ D + + + +GR S R
Sbjct: 746 LQWQEEERAH-------RQQQEEEQRRDFTWQWQAEEK--SERGRQRLSARPPLREQRER 796
Query: 895 TTRNEEQSRDGSRHSGSRHHEASSHADISRHSQAGQGQSEGSRTSRRQGSSVSQDSDSEG 954
R EE+ + R + + Q E + RR+ + Q+ + +G
Sbjct: 797 QLRAEERQQREQRFLPEEEEKEQRRRQRREREKELQFLEEEEQLQRRERAQQLQE-EEDG 855
Query: 955 HSEDSE-RWSGSASRNHRGSAQ-EQSRHGSRH 984
ED E R S R+ + Q E+ R RH
Sbjct: 856 LQEDQERRRSQEQRRDQKWRWQLEEERKRRRH 887
Score = 47.4 bits (111), Expect = 3e-04
Identities = 45/219 (20%), Positives = 89/219 (40%), Gaps = 16/219 (7%)
Query: 100 KHRKHSHHDK----HEDNKQEENKENRKRPSSLERRNNRKGNKGRSKSPRETGGKRHESS 155
K R+H+ + K + K+++ + + E R R+ + + E ++ E
Sbjct: 883 KRRRHTLYAKPALQEQLRKEQQLLQEEEEELQREEREKRRRQEQERQYREEEQLQQEEEQ 942
Query: 156 SEKKERKGYSPTHREEEYGKNHHNSSKKEK---NKTENTRLGDNRKRLSERLEEKEDNEE 212
++ER+ RE +Y K+ K+E+ + E R + K+ E EE + EE
Sbjct: 943 LLREEREKRRRQERERQYRKDKKLQQKEEQLLGEEPEKRRRQEREKKYREE-EELQQEEE 1001
Query: 213 GVYDYENTGRMTQKWIQSGHIATYYTIQDEAYDTTDSLLEENKIYERSRSSDGKSSSQVN 272
+ E R Q+W + Y +DE + LL E + E+ R + + +
Sbjct: 1002 QLLREEREKRRRQEWERQ------YRKKDELQQEEEQLLREER--EKRRLQERERQYREE 1053
Query: 273 RSRHENTSQVPLQESRTRKRRGSRVSQDRDSEGHSEDSE 311
+ Q+ +E TR+R+ ++ E E+ +
Sbjct: 1054 EELQQEEEQLLGEERETRRRQELERQYRKEEELQQEEEQ 1092
Score = 43.5 bits (101), Expect = 0.004
Identities = 160/937 (17%), Positives = 286/937 (30%), Gaps = 105/937 (11%)
Query: 109 KHEDNKQEENKENRKRPSSLERRNNRKGNKGRSKSPRETGGKRHESSSEKKERKGYSPTH 168
K E+ +QEE + R+ P R+ + + + +E E EK+ R+ +
Sbjct: 1082 KEEELQQEEEQLLREEPEKRRRQERERQCREEEELQQEEEQLLREER-EKRRRQELERQY 1140
Query: 169 REEEYGKNHHNSSKKEKNKTENTRLGDNRKRLSERLEE------KEDNEEGVYDYENTGR 222
REEE + +E+ + + + + R E L++ +E+ E+ + E R
Sbjct: 1141 REEEEVQQEEEQLLREEPEKRRRQELERQYREEEELQQEEEQLLREEQEKRRQERERQYR 1200
Query: 223 MTQKWIQSGHIATYYTIQDEAYD-------TTDSLLEENKIYERSRSSDGKSSSQVNRSR 275
++ +Q Y +D+ D ++ + +NK+Y + R
Sbjct: 1201 EEEE-LQRQKRKQRYRDEDQRSDLKWQWEPEKENAVRDNKVYCKGR-------------- 1245
Query: 276 HENTSQVPLQESRTRKRRGSRVSQDRDSEGHSEDSERHSGS-ASRNHHGSAWEQ-SRDGS 333
EN L++S+ R R+ + Q E D E+ R+ H EQ R+
Sbjct: 1246 -ENEQFRQLEDSQLRDRQSQQDLQHLLGEQQERDREQERRRWQQRDRHFPEEEQLEREEQ 1304
Query: 334 RHPRSHDEDRASHGHSADSSRQSGTRHAETSSRGQTASSHEQAR-SSPGERHGSGHQQSA 392
+ + D R+ R ET + + Q R P R +
Sbjct: 1305 KEAKRRDRKSQEEKQLLREEREEKRRRQETDRKFREEEQLLQEREEQPLRRQERDRKFRE 1364
Query: 393 DSSRHSATGRGQASSAVSDRGHRGSSGSQASDSEGHSENSDTQSVSGHGKAGLRQQSHQE 452
+ RH GR R + + + + Q + R++ Q
Sbjct: 1365 EELRHQEQGRKFLEEEQRLRRQERERKFLKEEQQLRCQEREQQLRQDRDRK-FREEEQQL 1423
Query: 453 STRGRSGERSGRSGSSLYQVSTHEQPDSAHGRTGTSTGGRQGSHHEQARDSSRHSASQEG 512
S + ER + QV E+ R+ EQ RH +E
Sbjct: 1424 SRQ----ERDRKFREEEQQVRRQERE-------------RKFLEEEQQLRQERHRKFREE 1466
Query: 513 QDTIRGHPGSSRGGRQGSHHEQSVNRSGHSGSHHSHTTSQGRSDASHGQSGSRSASRQTR 572
+ ++ EQ ++R R + S++
Sbjct: 1467 EQLLQ------------EREEQQLHRQERDRKFLEEEQQLRRQERDRKFREQELRSQEPE 1514
Query: 573 NEEQSGDGTRHSGSRHHEASSQADSSRHSQVGQGQSSGPRTSRNQGSSVSQDSDSQGHSE 632
+ + H R + + R + GQ R Q + Q E
Sbjct: 1515 RKFLEEEQQLHRQQRQRKFLQEEQQLRRQERGQ--------QRRQDRDRKFREEEQLRQE 1566
Query: 633 DSERWSGSASRNHHGSAQEQSRDGSRHPRSHHEDRAGHGHSADSSRKSGTRHTQNSSSGQ 692
E+ R+ +EQ R ED + R + Q
Sbjct: 1567 REEQQLSRQERDRKFRLEEQKVRRQEQERKFMEDEQQLRRQEGQQQLRQERDRKFREDEQ 1626
Query: 693 AASSHEQARSSAGERHGSRHQLQSADSSRHSGTGHGQASSAVRDSGHRGSSGSQATDSEG 752
E+ + ER R L+ R + +R R + EG
Sbjct: 1627 LLQEREEQQLHRQER--DRKFLEEEPQLRRQ-----EREQQLRHDRDRKFREEEQLLQEG 1679
Query: 753 HSEDSDTQSVSGHGQAGHHQQSHQESARDRSGERSRRSGSFLYQVSTHKQSESSHGWTGP 812
+ Q ++ +E + R ER R+ FL + ++ E +
Sbjct: 1680 EEQQLRRQE--------RDRKFREEEQQLRRQERERK---FLQEEQQLRRQELERKFR-E 1727
Query: 813 STGVRQGSHHEQARDNSRHSASQDGQDTIRGHPGSSRRGRQGSHHEQSVDRSGHSGSHHS 872
+RQ + EQ R R+ + ++ +R R +Q E+
Sbjct: 1728 EEQLRQETEQEQLRRQERYRKILE-EEQLR----PEREEQQLRRQERDRKFREEEQLRQE 1782
Query: 873 HTTSQGRSDASRGQSGSRSASRTTRNEEQSRDGSRHSGSRHHEASSHADISRHSQAGQGQ 932
Q RS S + R R E+Q R R R E + Q + +
Sbjct: 1783 REEQQLRSQESDRKFREEEQLRQEREEQQLRPQQRDGKYRWEE----EQLQLEEQEQRLR 1838
Query: 933 SEGSRTSRRQGSSVSQDSDSEGHSEDSERWSGSASRNHRGSAQEQSRHGSRHPRSHHEDR 992
E R R + +Q+ + E+ E W + + + + + H R ++
Sbjct: 1839 QERDRQYRAEEQFATQE---KSRREEQELWQEEEQKRRQ---ERERKLREEHIRRQQKEE 1892
Query: 993 AGHGHSADSSRQSGTPHAETSSGGQAASSHEQARSSP 1029
H + Q G H G + RSSP
Sbjct: 1893 QRHRQVGEIKSQEGKGHGRLLEPGTHQFASVPVRSSP 1929
Score = 42.4 bits (98), Expect = 0.009
Identities = 44/236 (18%), Positives = 100/236 (42%), Gaps = 20/236 (8%)
Query: 80 KLAQAYYESTRKENLPISGHKHRKHSHHDKHEDNKQEEN---KENRKRPSSLERRNNRKG 136
+L Q E ++E + ++ + ++ + ++EE +E KR R RK
Sbjct: 904 QLLQEEEEELQREEREKRRRQEQERQYREEEQLQQEEEQLLREEREKRRRQERERQYRKD 963
Query: 137 NKGRSKSPRETGGKRHESSSEKKERKGYSPTHREEEYGKNHHNSSKKEKNKTENTRLGDN 196
K + K + G + + +++E+K +REEE + +E+ + + +
Sbjct: 964 KKLQQKEEQLLGEEPEKRRRQEREKK-----YREEEELQQEEEQLLREEREKRRRQEWER 1018
Query: 197 RKRLSERLEEKEDNEEGVYDYENTGRMTQKWIQSGHIATYYTIQDEAYDTTDSLLEENKI 256
+ R + L+++E E+ + + R+ ++ Q Y ++E + LL E +
Sbjct: 1019 QYRKKDELQQEE--EQLLREEREKRRLQERERQ-------YREEEELQQEEEQLLGEERE 1069
Query: 257 YERSRSSDGKSSSQVNRSRHENTSQVPLQESRTRKRRGSRVSQDRDSEGHSEDSER 312
R + + + + + E + L+E ++RR R Q R+ E ++ E+
Sbjct: 1070 TRRRQELERQYRKEEELQQEE---EQLLREEPEKRRRQERERQCREEEELQQEEEQ 1122
Score = 42.0 bits (97), Expect = 0.012
Identities = 85/473 (17%), Positives = 146/473 (30%), Gaps = 61/473 (12%)
Query: 1527 RSDASHGQSGPRSASRQTRNEEQSGDG-SRHSGSRHHEPSTRAGSSRHSQVGQGESAGSK 1585
R + H Q R R R +E+ D R + HE R + Q + K
Sbjct: 433 RHEQKHEQE--RREQRLKREQEERRDWLKREEETERHEQERRKQQLKRDQEEERRERWLK 490
Query: 1586 TSRRQGSSVSQDRDSEGHSEDSERRSESASRNHYGSAREQSRHGSRNPRSHQEDRASHGH 1645
+ + R+ + E ERR + R +Q + R QE+R
Sbjct: 491 LEEEERREQQERREQQLRREQEERREQRLKRQEEEERLQQRLRSEQQLRREQEERREQLL 550
Query: 1646 SAESSRQSGTRHAETSSGGQAASSQEQARSSPGERHGSRHQQSADSSTDSGTGRRQDSSV 1705
E ++ E + ++Q ER R ++ + + R + +
Sbjct: 551 KREEEKRLEQERREQRLKREQEERRDQLLKREEERRQQRLKREQEERLEQRLKREEVERL 610
Query: 1706 VGDSGNRGSSGSQASDSEGHSE--ESDTQSVSAHGQAGPHQQ------------------ 1745
+ + + E + +S+ Q Q QQ
Sbjct: 611 EQEERREQRLKREEPEEERRQQLLKSEEQEERRQQQLRREQQERREQRLKREEEEERLEQ 670
Query: 1746 ----SHQESTR---------GQSGER-SGRSGSFLYQVSTHEQSESAHGRTGPSTGGRQR 1791
H+E R Q+ ER R + +Q+ + + + + P QR
Sbjct: 671 RLKREHEEERREQELAEEEQEQARERIKSRIPKWQWQLESEADARQSKVYSRPRKQEGQR 730
Query: 1792 SRHEQARDSSRHSASQEGQDTIRGHPGSSRGGRQGSHYEQSVDSSGHSGSHHSHTTSQER 1851
R EQ R + + Q+ R H RQ EQ D + ++E+
Sbjct: 731 RRQEQEEKRRRRESELQWQEEERAH-------RQQQEEEQRRDFTW-------QWQAEEK 776
Query: 1852 SDVSRGQSGSRSVSRQTR------NEKQSGDGSRHSGSRHHEASSRADSSRHSQVGQGQS 1905
S+ R + +R R+ R E+Q + E R R ++ +
Sbjct: 777 SERGRQRLSARPPLREQRERQLRAEERQQREQRFLPEEEEKEQRRRQRREREKELQFLEE 836
Query: 1906 SGPRTSRNQGSSVSQDSDSQGHSEDSERWSGSASRNHLGSAW--EQSRDGSRH 1956
R + + ++ D G ED ER R W E+ R RH
Sbjct: 837 EEQLQRRERAQQLQEEED--GLQEDQERRRSQEQRRDQKWRWQLEEERKRRRH 887
Score = 32.7 bits (73), Expect = 7.5
Identities = 42/237 (17%), Positives = 78/237 (32%), Gaps = 24/237 (10%)
Query: 90 RKENLPISGHKHRKHSHHDKHEDNKQEENKENRKRPSSLERRNNRKGNKGRSKSPRETGG 149
R + P R+ K D K +E K+ + +RR K R +
Sbjct: 1289 RDRHFPEEEQLEREEQKEAKRRDRKSQEEKQLLREEREEKRRRQETDRKFREEEQLLQER 1348
Query: 150 KRHESSSEKKERKGYSPTHREEEYGK---------NHHNSSKKEKNKTENTRLGDNRKRL 200
+ ++++RK R +E G+ +K + + R + ++L
Sbjct: 1349 EEQPLRRQERDRKFREEELRHQEQGRKFLEEEQRLRRQERERKFLKEEQQLRCQEREQQL 1408
Query: 201 SERLEEKEDNEEGVYDYENTGRMTQKWIQSGHIATYYTIQDEAYDTTDSLLEENKIYERS 260
+ + K EE + R ++ Q Q + LEE + +
Sbjct: 1409 RQDRDRKFREEEQQLSRQERDRKFREEEQ----------QVRRQERERKFLEEEQQLRQE 1458
Query: 261 RSSDGKSSSQVNRSR-----HENTSQVPLQESRTRKRRGSRVSQDRDSEGHSEDSER 312
R + Q+ + R H E + RR R + R+ E S++ ER
Sbjct: 1459 RHRKFREEEQLLQEREEQQLHRQERDRKFLEEEQQLRRQERDRKFREQELRSQEPER 1515
>gi|6631100 natural killer-tumor recognition sequence [Homo sapiens]
Length = 1462
Score = 120 bits (301), Expect = 3e-26
Identities = 278/1344 (20%), Positives = 489/1344 (36%), Gaps = 152/1344 (11%)
Query: 2374 HSEDSDTQSVSAHGQAGPHQQS--HQESTRGRSAGRSG--RSGSFLYQVSTHEQSESAHG 2429
HSE SD+ S S+ + H+ S R + R RS + S+ E+ + H
Sbjct: 194 HSEGSDSSSNSSSSSESSSESELEHERSRRRKHKRRPKVKRSKKRRKEASSSEEPRNKHA 253
Query: 2430 RTGTSTGGRQGSHHKQARDSS-RHSTSQEGQDTIHGHPGSSSGGRQ------GSHYEQLV 2482
R ++ K++ DSS + + I P + R+ ++
Sbjct: 254 MNPKGHSERSDTNEKRSVDSSAKREKPVVRPEEIPPVPENRFLLRRDMPVVTAEPEPKIP 313
Query: 2483 DRSGHSGSHHSHTTSQGRSDASHG----HSGSRSASRQTRNDEQSGDGSRHSGSRHHEAS 2538
D + + GR G H+ RS S +D+ S + H
Sbjct: 314 DVAPIVSDQKPSVSKSGRKIKGRGTIRYHTPPRSRSCSESDDDDSSETPPHWKEEMQRLR 373
Query: 2539 SRADSSGHSQVGQGQSEGPRTSRNWGSSFSQDSDSQGHSEDSERWSGSASRNHHGSAQEQ 2598
+ SG + P +SR S SQ S S ++ S + HH +++
Sbjct: 374 AYRPPSGEKWSKGDKLSDPCSSRWDERSLSQRSRSWSYNGYYSDLSTARHSGHHKKRRKE 433
Query: 2599 LRDGSRHPRSHQEDRAGHGHSADSSRQ---SGTRHTQTSSGGQAASSHEQARSSAGERHG 2655
+ +H + ++ + H R+ + SS + SS ++ RSS
Sbjct: 434 KK--VKHKKKGKKQKHCRRHKQTKKRRILIPSDIESSKSSTRRMKSSCDRERSSRSSSLS 491
Query: 2656 SHHQQSADSSRHSGIGHGQASSAVRDSGHRGYSGSQASDNEGHSEDSDTQSVSAHGQAGS 2715
SHH D S+ + + RDS +R S SQ S + G S S+H ++ S
Sbjct: 492 SHHSSKRDWSKSDKDVQSSLTHSSRDS-YRSKSHSQ-SYSRGSSRSRTASKSSSHSRSRS 549
Query: 2716 HQQSHQESA-RGRSGETSGHSGSFLYQV---------STHEQSES--------------S 2751
+S +S R R+ ++ + S L + +T Q+E+
Sbjct: 550 KSRSSSKSGHRKRASKSPRKTASQLSENKPVKTEPLRATMAQNENVVVQPVVAENIPVIP 609
Query: 2752 HGWTGPSTRGRQGSR-----HEQAQD-SSRHSASQDGQDTIRGHPGSSRGGRQGYHHEHS 2805
+ P +R + G + +E+ Q+ ++ + Q T G YH
Sbjct: 610 LSDSPPPSRWKPGQKPWKPSYERIQEMKAKTTHLLPIQSTYSLANIKETGSSSSYHKREK 669
Query: 2806 VDSSGHS-----GSHHSHTTSQGRSDASRGQSGSRSASRTTRNEEQSGDGSRHSGSRHHE 2860
S S S ++ + RS +SR +S SRS +R+ R+ S SR SR H
Sbjct: 670 NSESDQSTYSKYSDRSSESSPRSRSRSSRSRSYSRSYTRS-RSLASSHSRSRSPSSRSHS 728
Query: 2861 ASTHADISRHSQAVQGQS----EGSRRSRRQGSSVSQDSDSEGHSEDSERWSGSASRNHH 2916
+ ++D S+ S++ S +G R RR SS ++S S ++ S S+ + H
Sbjct: 729 RNKYSDHSQCSRSSSYTSISSDDGRRAKRRLRSSGKKNSVSH------KKHSSSSEKTLH 782
Query: 2917 GSAQEQLRDGSRHPRSHQEDRAGHGHSADSSRQSGTRHTQTSSG----GQAASSHEQARS 2972
S + RD S R + E R+ +S+DS QS + TQ++ GQ +H +
Sbjct: 783 -SKYVKGRDRSSCVRKYSESRSSLDYSSDSE-QSSVQATQSAQEKEKQGQMERTHNKQEK 840
Query: 2973 SAGERHGSHHQQSADSSRHSGIGHGQASSAVRDSG---HRGYSGSQASDNEGHSEDSDTQ 3029
+ GE ++ S + + S +R+ + Y+GS+ D+E +SE +
Sbjct: 841 NRGEEKSKSERECPHSKKRTL--KENLSDHLRNGSKPKRKNYAGSKW-DSESNSE----R 893
Query: 3030 SVSAHGQAGSHQQSHQESARGRSGETSGHSGSFLYQVSTHEQSESSHGWTGPSTRGRQGS 3089
V+ + + SH S +E S S S + ++SS + P G S
Sbjct: 894 DVTKNSKNDSHPSSDKEEGEATSDSESEVSE---IHIKVKPTTKSSTNTSLPDDNGAWKS 950
Query: 3090 RHEQAQDSSRHSASQYGQDTIRGHPGSSR-GGRQGYHHEHSVDSSGH-SGSHHSHTTSQG 3147
++ S + ++ RG P + G ++ EH+ G +
Sbjct: 951 SKQRTSTSDSEGSCSNSENN-RGKPQKHKHGSKENLKREHTKKVKEKLKGKKDKKHKAPK 1009
Query: 3148 RSDASRGQSGSRSASRTTRNEEQSGDSSRHSVSRHHEASTHAD-ISRHSQAVQGQSEGSR 3206
R A Q EE+ D S+ + S + + I + + SE
Sbjct: 1010 RKQAFHWQPPLEFGEE---EEEEIDDKQVTQESKEKKVSENNETIKDNILKTEKSSEEDL 1066
Query: 3207 RSRRQGSSVSQDSDSEGHSEDSERWSGSASRNHRGSVQ--EQSRHGSRHPRSHHEDRAGH 3264
+ +VS D D + +DS+ + N +V + +H + ED
Sbjct: 1067 SGKHDTVTVSSDLD-QFTKDDSKLSISPTALNTEENVACLQNIQHVEESVPNGVEDVLQT 1125
Query: 3265 GHSAD---RSRQSGTRHAETSSGGQAASSHEQARSSPGERHGSRHQQSADSSRHSGIPRG 3321
+ + R S + ETS G A + + H Q+ + S +
Sbjct: 1126 DDNMEICTPDRSSPAKVEETSPLGNARLDTPDINIVLKQDMATEHPQAEVVKQESSMSES 1185
Query: 3322 QASSAVRDSRHWGSSGSQASDSEGHSEESDTQSVSGHGQAGPHQQSHQESARDRSGGRSG 3381
+ V +S + A +S G E ++ ++ + Q A + S
Sbjct: 1186 KVLGEVGKQDSSSASLASAGESTGKKEVAEKSQINLIDKKWKPLQGVGNLAAPNAATSSA 1245
Query: 3382 RSGSFLYQVSTHEQSESAHGRTRTSTGRRQGSHHEQARDSSRHSASQEGQDTIRGHPGSS 3441
L V + + ++ R GS ++ R ++R + Q++
Sbjct: 1246 VEVKVLTTVP-EMKPQGLRIEIKSKNKVRPGSLFDEVRKTARLNRRPRNQES-------- 1296
Query: 3442 RRGRQGSHYEQSVDRSGHSGSHHSHTTSQGRSDASRGQSGSRSASRQTRNDEQSGDGSRH 3501
S + R D S+ +S SRS S+ S SRH
Sbjct: 1297 ----------------------SSDEQTPSRDDDSQSRSPSRSRSK-------SETKSRH 1327
Query: 3502 SWSHHHEASTQADSSRHSQSGQGQSAGPRTSRNQGSSVSQDSDSQGHSEDSERWSGSASR 3561
T++ S HS+S S SR+ S S+ S+G + S S + +
Sbjct: 1328 R--------TRSVSYSHSRSRSRSSTSSYRSRSYSRSRSRGWYSRGRTR-SRSSSYRSYK 1378
Query: 3562 NHRGSAQEQSRDGSRHPTSH-----HEDRAGHGHSAESSRQSGTHHAENSSGGQAASSHE 3616
+HR S++ +SR S P S ++ S S++S ++H S ++ S
Sbjct: 1379 SHRTSSRSRSRSSSYDPHSRSRSYTYDSYYSRSRSRSRSQRSDSYHRGRSYNRRSRSCRS 1438
Query: 3617 QARSSAGERHGSHHQQSADSSRHS 3640
S +R SHH+ ++SSR+S
Sbjct: 1439 YGSDSESDRSYSHHRSPSESSRYS 1462
Score = 112 bits (281), Expect = 6e-24
Identities = 272/1323 (20%), Positives = 466/1323 (35%), Gaps = 228/1323 (17%)
Query: 87 ESTRKENLPISGHKHRKHSHHDKHEDNKQEENKENRKRPSSLERRNNRKGNKGRSKSPR- 145
ES+ + L + RKH K + +K+ RK SS E N+ + S R
Sbjct: 209 ESSSESELEHERSRRRKHKRRPK-----VKRSKKRRKEASSSEEPRNKHAMNPKGHSERS 263
Query: 146 ETGGKRHESSSEKKERKGYSPTHREEEYGKNHHN-------------------------- 179
+T KR SS K+E+ P R EE N
Sbjct: 264 DTNEKRSVDSSAKREK----PVVRPEEIPPVPENRFLLRRDMPVVTAEPEPKIPDVAPIV 319
Query: 180 ---------SSKKEKNKTENTRLGDNRKRLSERLEEKEDNEEGVYDYENTGRMTQKWIQS 230
S +K K + R R ++ + +E + E R+ S
Sbjct: 320 SDQKPSVSKSGRKIKGRGTIRYHTPPRSRSCSESDDDDSSETPPHWKEEMQRLRAYRPPS 379
Query: 231 GHIATYYTIQDEAYDTTDSLLEENKIYERSRS-SDGKSSSQVNRSRHENTSQVPLQESRT 289
G ++ D+ D S +E + +RSRS S S ++ +RH + +E +
Sbjct: 380 GE---KWSKGDKLSDPCSSRWDERSLSQRSRSWSYNGYYSDLSTARHSGHHKKRRKEKKV 436
Query: 290 R-----------------KRRGSRVSQDRDSEGHSE-------DSERHSGSASRNHHGSA 325
+ K+R + D +S S D ER S S+S + H S+
Sbjct: 437 KHKKKGKKQKHCRRHKQTKKRRILIPSDIESSKSSTRRMKSSCDRERSSRSSSLSSHHSS 496
Query: 326 ---WEQSRDGSRHPRSHDEDRASHGHSADSSRQSGTRHAETSSRGQTASSHEQARSSPGE 382
W +S + +H + S S G+ + T+S+ +SSH ++RS
Sbjct: 497 KRDWSKSDKDVQSSLTHSSRDSYRSKSHSQSYSRGSSRSRTASK---SSSHSRSRSKSRS 553
Query: 383 RHGSGHQQSADSSRHSATGRGQASSAVSDRGHRGSSGSQASDSEGHSENSDTQSVSGHGK 442
SGH++ A S + + V R + +EN Q V
Sbjct: 554 SSKSGHRKRASKSPRKTASQLSENKPVKTEPLRATM--------AQNENVVVQPVVAENI 605
Query: 443 AGLRQQSHQESTRGRSGERSGRSGSSLYQ----VSTHEQP-DSAHGRTGTSTGGRQGSHH 497
+ +R + G++ + Q +TH P S + G S+H
Sbjct: 606 PVIPLSDSPPPSRWKPGQKPWKPSYERIQEMKAKTTHLLPIQSTYSLANIKETGSSSSYH 665
Query: 498 --EQARDSSRHSASQEGQDTIRGHPGSSRGGRQGSHHEQSVNRSGHSGSHHSHTTS-QGR 554
E+ +S + + S+ + P S + + +S RS S HS + S R
Sbjct: 666 KREKNSESDQSTYSKYSDRSSESSPRSRSRSSRSRSYSRSYTRSRSLASSHSRSRSPSSR 725
Query: 555 SDASHGQSGSRSASRQTRNEEQSGDGTRHSGSR-----------HHEASSQADSSRHSQV 603
S + + S SR + S D R + R H + SS ++ + HS+
Sbjct: 726 SHSRNKYSDHSQCSRSSSYTSISSDDGRRAKRRLRSSGKKNSVSHKKHSSSSEKTLHSKY 785
Query: 604 --GQGQSSGPRTSRNQGSSVSQDSDSQ------GHSEDSERWSGSASRNHHGSAQEQSRD 655
G+ +SS R SS+ SDS+ S + G R H+ + + +
Sbjct: 786 VKGRDRSSCVRKYSESRSSLDYSSDSEQSSVQATQSAQEKEKQGQMERTHNKQEKNRGEE 845
Query: 656 GSRHPRS--HHEDRAGHGHSADSSRKSGTRHTQNSS----SGQAASSHEQARSSAGERHG 709
S+ R H + R + +D R +N + ++ S + ++S + H
Sbjct: 846 KSKSERECPHSKKRTLKENLSDHLRNGSKPKRKNYAGSKWDSESNSERDVTKNSKNDSHP 905
Query: 710 SRHQLQSADSS-----------RHSGTGHGQASSAVRDSGHRGSSGSQATDSEGHSEDSD 758
S + + +S + T ++++ D S Q T S SE S
Sbjct: 906 SSDKEEGEATSDSESEVSEIHIKVKPTTKSSTNTSLPDDNGAWKSSKQRT-STSDSEGSC 964
Query: 759 TQSVSGHGQAGHHQQSHQESARDRSGE--RSRRSGSFLYQVSTHKQSESSHGWTGPSTGV 816
+ S + G+ H+ +E+ + + + + G + K+ ++ H W P +
Sbjct: 965 SNSENNRGKPQKHKHGSKENLKREHTKKVKEKLKGKKDKKHKAPKRKQAFH-WQPP---L 1020
Query: 817 RQGSHHEQARDN------SRHSASQDGQDTIRGH----PGSSRRGRQGSHHEQSV----- 861
G E+ D+ S+ + +TI+ + SS G H +V
Sbjct: 1021 EFGEEEEEEIDDKQVTQESKEKKVSENNETIKDNILKTEKSSEEDLSGKHDTVTVSSDLD 1080
Query: 862 ----DRSGHSGSHHSHTTSQGRSDASRGQSGSRSASRTTRNEEQSRDGSRHSGSRHHEAS 917
D S S S + T + + Q S + Q+ D + S
Sbjct: 1081 QFTKDDSKLSISPTALNTEENVACLQNIQHVEESVPNGVEDVLQTDDNMEICTP---DRS 1137
Query: 918 SHADISRHSQAGQGQ----------SEGSRTSRRQGSSVSQD---SDSEGHSEDSERWSG 964
S A + S G + + T Q V Q+ S+S+ E ++ S
Sbjct: 1138 SPAKVEETSPLGNARLDTPDINIVLKQDMATEHPQAEVVKQESSMSESKVLGEVGKQDSS 1197
Query: 965 SASRNHRGSAQEQSRHGSRHPRSHHEDR----AGHGHSADSSRQSGTPHAETSSGGQA-- 1018
SAS G + + + + + + G G+ A P+A TSS +
Sbjct: 1198 SASLASAGESTGKKEVAEKSQINLIDKKWKPLQGVGNLA-------APNAATSSAVEVKV 1250
Query: 1019 ---------ASSHEQARSSPGERHGSRHQQSADSSRHSGIPRRQASSAVRDSGHWGSSGS 1069
+ +S R GS + ++R + PR Q SS
Sbjct: 1251 LTTVPEMKPQGLRIEIKSKNKVRPGSLFDEVRKTARLNRRPRNQESS------------- 1297
Query: 1070 QASDSEGHSEESDTQSVSGHGQDGPHQQSHQESARDWSGGRSGRSGSFIYQVSTHEQSES 1129
SD + S + D+QS S S S + RS S+ + S S S
Sbjct: 1298 --SDEQTPSRDDDSQSRS---------PSRSRSKSETKSRHRTRSVSYSHSRSRSRSSTS 1346
Query: 1130 AHGRTRTSTGRRQGSHHEQARDSSRHSASQEGQDTIRAH-PGSRRGGRQGSHHEQSVDRS 1188
++ R+R+ + R + + R SR S+ + + ++H SR R S+ S RS
Sbjct: 1347 SY-RSRSYSRSRSRGWYSRGRTRSRSSSYR----SYKSHRTSSRSRSRSSSYDPHSRSRS 1401
Query: 1189 GHSGSHHSHTTSQGRSDASHGQSGSRSASRQTRKDKQSGDGSRHSGS-RHHEAASWADSS 1247
S++S + S+ RS S RS +R++R + G S S HH + S +SS
Sbjct: 1402 YTYDSYYSRSRSRSRSQRSDSYHRGRSYNRRSRSCRSYGSDSESDRSYSHHRSPS--ESS 1459
Query: 1248 RHS 1250
R+S
Sbjct: 1460 RYS 1462
Score = 109 bits (273), Expect = 5e-23
Identities = 283/1349 (20%), Positives = 466/1349 (34%), Gaps = 133/1349 (9%)
Query: 675 DSSRKSGTRHTQNSSSGQAASSHEQARSSAGERHGSRHQLQSADSS-RHSGTGHGQASSA 733
+ RK T + SS ++SS E + S E SR + + S +ASS+
Sbjct: 186 EKKRKKPTHSEGSDSSSNSSSSSESSSESELEHERSRRRKHKRRPKVKRSKKRRKEASSS 245
Query: 734 VRDSGHRGSSGSQATDSEGHSEDSDTQSVSGHGQAGHHQ-------------QSHQESAR 780
A + +GHSE SDT + + ++ R
Sbjct: 246 EEPRN------KHAMNPKGHSERSDTNEKRSVDSSAKREKPVVRPEEIPPVPENRFLLRR 299
Query: 781 DR---SGERSRRSGSFLYQVSTHKQSESSHGWTGPSTGVRQGSHHEQARDNSRHSASQDG 837
D + E + VS K S S G G + +H R SR + D
Sbjct: 300 DMPVVTAEPEPKIPDVAPIVSDQKPSVSKSGRKIKGRGTIR--YHTPPR--SRSCSESDD 355
Query: 838 QDTIRGHPGSSRRGRQGSHHEQSVDRSGHSGSHHSHTTSQGRSDASRGQSGSRSASRTTR 897
D+ P ++ + G S S + S Q RS S +
Sbjct: 356 DDSSETPPHWKEEMQRLRAYRPPSGEKWSKGDKLSDPCSSRWDERSLSQ---RSRSWSYN 412
Query: 898 NEEQSRDGSRHSGSRHHEASSHADISRHSQAGQGQSEGSRTSRRQGSSVSQDSDSEGHSE 957
+RHSG HH+ +H + G+ Q R + + + SD E
Sbjct: 413 GYYSDLSTARHSG--HHKKRRKEKKVKHKKKGKKQKHCRRHKQTKKRRILIPSDIESSKS 470
Query: 958 DSERWSGSASRNHRGSAQEQSRHGSRHPRSHHEDRAGHGHSADSSRQS--GTPHAETSSG 1015
+ R S R + S H S D+ SSR S H+++ S
Sbjct: 471 STRRMKSSCDRERSSRSSSLSSHHSSKRDWSKSDKDVQSSLTHSSRDSYRSKSHSQSYSR 530
Query: 1016 GQA-------ASSHEQARSSPGERHGSRHQQSADSSRHSGIPRRQASSAVRDSGHWGSSG 1068
G + +SSH ++RS S H++ A S PR+ A S + ++ +
Sbjct: 531 GSSRSRTASKSSSHSRSRSKSRSSSKSGHRKRASKS-----PRKTA-SQLSENKPVKTEP 584
Query: 1069 SQASDSEGHSEESDTQSVSGHG------QDGPHQQSHQESARDWSGGRSGRSGSFIYQVS 1122
+A+ ++ +E Q V D P + + W Y+
Sbjct: 585 LRATMAQ--NENVVVQPVVAENIPVIPLSDSPPPSRWKPGQKPWKPS---------YERI 633
Query: 1123 THEQSESAHGRTRTSTGRRQGSHHEQARDSSRHSASQEGQDTIRAHPGSRRGGRQGSHHE 1182
++++ H ST + E SS H + + Q ++ +
Sbjct: 634 QEMKAKTTHLLPIQST-YSLANIKETGSSSSYHKREKNSESD------------QSTYSK 680
Query: 1183 QSVDRSGHSGSHHSHTTSQGRSDASHGQSGSRSASRQTRKDKQSGDGSRHSGSRHHEAAS 1242
S DRS S ++ + RS +S +S SRS +R +R S SR SR H
Sbjct: 681 YS-DRS-------SESSPRSRSRSSRSRSYSRSYTR-SRSLASSHSRSRSPSSRSHSRNK 731
Query: 1243 WADSSRHSQVGQEQSSGSRTSRHQGSSVSQDSDSERHSDDSERLSGSASRNHHGSSREQS 1302
++D S+ S+ S S R + S +++S ++ S S+ + H S +
Sbjct: 732 YSDHSQCSRSSSYTSISSDDGRRAKRRLR--SSGKKNSVSHKKHSSSSEKTLH-SKYVKG 788
Query: 1303 RDGSRHPGFHQEDRASHGHSADSSRQSGTHHTESSSHGQAVSSHEQARSSPGERHGSRHQ 1362
RD S + E R+S +S+D S QS T+S+ + E+ + + G
Sbjct: 789 RDRSSCVRKYSESRSSLDYSSD-SEQSSVQATQSAQEKEKQGQMERTHNKQEKNRGEEKS 847
Query: 1363 QSADSSRHSGIGHRQASSAVRDSGHRGSSGSQ--VTNSEGHSEDSDTQSVSAHGQAGPHQ 1420
+S HS R + D GS + S+ SE + + V+ + + H
Sbjct: 848 KSERECPHS--KKRTLKENLSDHLRNGSKPKRKNYAGSKWDSESNSERDVTKNSKNDSHP 905
Query: 1421 QSHKESARGQSGESSGRSRSFLYQVSSHEQSESTHGQTAPSTGGRQGSRHEQARNSSRHS 1480
S KE S S S + ++S+ + P G S ++ S
Sbjct: 906 SSDKEEGEATSDSESEVSE---IHIKVKPTTKSSTNTSLPDDNGAWKSSKQRTSTSDSEG 962
Query: 1481 ASQDGQDTIRGHPGSSRGGRQGSY---HEQSVDRSGHSGYHHSHTTPQGRSDASHGQSGP 1537
+ + ++ RG P + G + + H + V H P+ R A H Q
Sbjct: 963 SCSNSENN-RGKPQKHKHGSKENLKREHTKKVKEKLKGKKDKKHKAPK-RKQAFHWQPPL 1020
Query: 1538 RSASRQTRNEEQSGDGSRHSGSRHHEPSTRAGSSRHSQVGQGESAGSKTSRRQGS-SVSQ 1596
+ EE+ D S+ + S + + + + +S+ S + + +VS
Sbjct: 1021 EFGEEE---EEEIDDKQVTQESKEKKVSENNETIKDNILKTEKSSEEDLSGKHDTVTVSS 1077
Query: 1597 DRDSEGHSEDSERRSESASRNHYGSAREQS-RHGSRNPRSHQEDRASHGHSAE---SSRQ 1652
D D + S +A A Q+ +H + + ED + E R
Sbjct: 1078 DLDQFTKDDSKLSISPTALNTEENVACLQNIQHVEESVPNGVEDVLQTDDNMEICTPDRS 1137
Query: 1653 SGTRHAETSSGGQAASSQEQARSSPGERHGSRHQQSADSSTDSGTGRRQDSSVVGDSGNR 1712
S + ETS G A + + H Q+ +S +S V+G+ G +
Sbjct: 1138 SPAKVEETSPLGNARLDTPDINIVLKQDMATEHPQAEVVKQESS---MSESKVLGEVGKQ 1194
Query: 1713 GSSG---SQASDSEGHSEESDTQSVSAHGQAGPHQQSHQESTRGQSGERSGRSGSFLYQV 1769
SS + A +S G E ++ ++ + Q + S L V
Sbjct: 1195 DSSSASLASAGESTGKKEVAEKSQINLIDKKWKPLQGVGNLAAPNAATSSAVEVKVLTTV 1254
Query: 1770 STHEQSESAHGRTGPSTGGRQRSRHEQARDSSRHSASQEGQDTIRGHPGSSRGGRQGSHY 1829
+ + R S ++ R ++R + Q++ SR S
Sbjct: 1255 -PEMKPQGLRIEIKSKNKVRPGSLFDEVRKTARLNRRPRNQESSSDEQTPSRDDDSQSRS 1313
Query: 1830 EQSVDSSGHSGSHH-------SHTTSQERSDVS--RGQSGSRSVSR--QTRNEKQSGDGS 1878
S + S H SH+ S+ RS S R +S SRS SR +R +S S
Sbjct: 1314 PSRSRSKSETKSRHRTRSVSYSHSRSRSRSSTSSYRSRSYSRSRSRGWYSRGRTRSRSSS 1373
Query: 1879 RHSGSRHHEAS-SRADSSRHSQVGQGQS--SGPRTSRNQGSSVSQDSDSQGHSEDSERWS 1935
S H +S SR+ SS + + +S SR++ S SQ SDS R S
Sbjct: 1374 YRSYKSHRTSSRSRSRSSSYDPHSRSRSYTYDSYYSRSRSRSRSQRSDSYHRGRSYNRRS 1433
Query: 1936 GSASRNHLGSAWEQSRDGSRHPGSHHEDR 1964
S GS E R S H R
Sbjct: 1434 RSC--RSYGSDSESDRSYSHHRSPSESSR 1460
Score = 103 bits (257), Expect = 3e-21
Identities = 295/1451 (20%), Positives = 497/1451 (34%), Gaps = 250/1451 (17%)
Query: 1396 TNSEGHSEDSDTQSVSAHGQAGPHQQSHKESARGQSGESSGRSRSFLYQVSSHEQSESTH 1455
T+SEG S++ S S + + + RS+ + SS E+ + H
Sbjct: 193 THSEGSDSSSNSSSSSESSSESELEHERSRRRKHKRRPKVKRSKKRRKEASSSEEPRNKH 252
Query: 1456 GQTAPSTGGRQGSRHEQARNSSRHSASQDGQD--------------------TIRGHPGS 1495
R + +++ +SS + T P
Sbjct: 253 AMNPKGHSERSDTNEKRSVDSSAKREKPVVRPEEIPPVPENRFLLRRDMPVVTAEPEPKI 312
Query: 1496 SRGGRQGSYHEQSVDRSGHS----GYHHSHTTPQGRSDASHGQSGPRSASRQTRNEEQSG 1551
S + SV +SG G HT P+ RS + E
Sbjct: 313 PDVAPIVSDQKPSVSKSGRKIKGRGTIRYHTPPRSRSCS-----------------ESDD 355
Query: 1552 DGSRHSGSRHHEPSTRAGSSRHSQVGQGESAGSKTSRRQGSSVSQDRDSEGHSEDSERRS 1611
D S + E R + R +G K S+ G +S S +RS
Sbjct: 356 DDSSETPPHWKEEMQRLRAYR-------PPSGEKWSK--GDKLSDPCSSRWDERSLSQRS 406
Query: 1612 ESASRNHYGSAREQSRHGSRNPRSHQEDRASHGHSAESSRQSGTRHAETSSGGQAASSQE 1671
S S N Y S +RH + + +E + H + + RH +T
Sbjct: 407 RSWSYNGYYSDLSTARHSGHHKKRRKEKKVKHKKKGKKQKHC-RRHKQTKK--------- 456
Query: 1672 QARSSPGERHGSRHQQSADSSTDSGTGRRQDSSVVGDSGNRGSSGSQ--ASDSEGHSEES 1729
R +D + + RR SS + +R SS S +S + +
Sbjct: 457 -----------RRILIPSDIESSKSSTRRMKSSCDRERSSRSSSLSSHHSSKRDWSKSDK 505
Query: 1730 DTQSVSAHGQAGPHQ-QSHQES-TRGQSGERSGRSGSFLYQVSTHEQSESAHGRTGPSTG 1787
D QS H ++ +SH +S +RG S R+ S +H +S S R+ +G
Sbjct: 506 DVQSSLTHSSRDSYRSKSHSQSYSRGSSRSRTASKSS------SHSRSRSK-SRSSSKSG 558
Query: 1788 GRQRSRHEQARDSSRHSASQEGQDT-IRGHPGSSRGGRQGSHYEQSV-----------DS 1835
R+R A S R +ASQ ++ ++ P + + + Q V DS
Sbjct: 559 HRKR-----ASKSPRKTASQLSENKPVKTEPLRATMAQNENVVVQPVVAENIPVIPLSDS 613
Query: 1836 ---SGHSGSHHSHTTSQERSDVSRGQSGSRSVSRQT---RNEKQSGDGSRHSGSRHHEAS 1889
S S ER + ++ + T N K++G S + E +
Sbjct: 614 PPPSRWKPGQKPWKPSYERIQEMKAKTTHLLPIQSTYSLANIKETGSSSSY---HKREKN 670
Query: 1890 SRADSSRHSQVGQGQSSGPRTSRNQGSSVSQDSDSQGHSEDSERWSGSASRNHLGSAWEQ 1949
S +D S +S+ R+S + S S+ S S+ +S R AS
Sbjct: 671 SESDQSTYSKYSD------RSSESSPRSRSRSSRSRSYSRSYTRSRSLAS---------- 714
Query: 1950 SRDGSRHPGSHHEDRAGHGHSADSSRQSGTRHTESSSRGQAASSHEQARSSAGERHGSHH 2009
S SR P S R + + SR S S +A ++ S+G+++ H
Sbjct: 715 SHSRSRSPSSRSHSRNKYSDHSQCSRSSSYTSISSDDGRRA----KRRLRSSGKKNSVSH 770
Query: 2010 QLQSADSSR--HSGIGHGQASSAVRDSGHRGYSGSQASDSEGHSEDSDTQSVSAQGKAGP 2067
+ S+ S + HS G+ R S R YS S++S +S DS+ SV A
Sbjct: 771 KKHSSSSEKTLHSKYVKGRD----RSSCVRKYSESRSSLD--YSSDSEQSSVQAT----- 819
Query: 2068 HQQSHKESARGQSGESSGRSGSFLYQVSTHEQSESTHGQSAPSTGGRQGSHYDQAQDSSR 2127
QS + + G Q E TH + + G + + S +
Sbjct: 820 -----------QSAQEKEKQG----------QMERTHNKQEKNRGEEKSKSERECPHSKK 858
Query: 2128 HSASQEGQDTIRGHPGPSRGGRQGS------HQEQSVDRSGHSGSHHSHTTSQGRSDASR 2181
+ + D +R P R GS + E+ V ++ + SH S +G +
Sbjct: 859 RTLKENLSDHLRNGSKPKRKNYAGSKWDSESNSERDVTKNSKNDSHPSSDKEEGEAT--- 915
Query: 2182 GQSGSRSASRKTYDKEQSGDGSRHSGSHHHEASSWADSSRHSLVGQGQSSGPRTSRPRGS 2241
S S S + + K + S + S + +W +SS RTS
Sbjct: 916 --SDSESEVSEIHIKVKPTTKSSTNTSLPDDNGAW------------KSSKQRTST---- 957
Query: 2242 SVSQDSDSEGHSEDSERRSGSASRNHHGSAQEQSRDGSRHPRSHHEDRAGHGHSAESSRQ 2301
SDSEG +SE G ++ HGS + R+ ++ + + + H A +Q
Sbjct: 958 -----SDSEGSCSNSENNRGKPQKHKHGSKENLKREHTKKVKEKLKGKKDKKHKAPKRKQ 1012
Query: 2302 SGTHHAENSSGGQAAS--SHEQARSSAGERHGSHHQQSADSSRHSGIGHGQASSAVRDSG 2359
+ G + +Q + E+ S + ++ + S+ D
Sbjct: 1013 AFHWQPPLEFGEEEEEEIDDKQVTQESKEKKVSENNETIKDNILK-----TEKSSEEDLS 1067
Query: 2360 HRGSSGSQASDSEGHSEDSDTQSVS------AHGQAGPHQQSHQESTRGRSAGRSGRSGS 2413
+ + + +SD + ++D S+S A H E + ++
Sbjct: 1068 GKHDTVTVSSDLDQFTKDDSKLSISPTALNTEENVACLQNIQHVEESVPNGVEDVLQTDD 1127
Query: 2414 FLYQVSTHEQSESAHGRTGTSTGGRQGSHHKQARDSSRHSTSQEGQDTIHGHPGSSSGGR 2473
+ ++ T ++S A + G AR + QD HP + +
Sbjct: 1128 NM-EICTPDRSSPAKVEETSPLG--------NARLDTPDINIVLKQDMATEHPQAEVVKQ 1178
Query: 2474 QGSHYEQLVDRSGHSGSHHSHTTSQGRSDASHGHSGSRSASRQTRNDE--QSGDGSRHSG 2531
+ S E V G G S + S + S G S+ D+ + G +
Sbjct: 1179 ESSMSESKV--LGEVGKQDSSSASLASAGESTGKKEVAEKSQINLIDKKWKPLQGVGNLA 1236
Query: 2532 SRHHEASSRADSSGHSQVGQGQSEGPRTSRNWGSSFSQDSDSQGHSEDSERWSGSASR-- 2589
+ + SS + + V + + +G R S++ G D R + +R
Sbjct: 1237 APNAATSSAVEVKVLTTVPEMKPQGLRIEIK-----SKNKVRPGSLFDEVRKTARLNRRP 1291
Query: 2590 -NHHGSAQEQL--RDGSRHPRSHQEDRAGHGHSADSSRQSGTRHTQTSSGGQAASSHEQA 2646
N S+ EQ RD RS R S ++ +RH S + SH ++
Sbjct: 1292 RNQESSSDEQTPSRDDDSQSRSPSRSR--------SKSETKSRHRTRS----VSYSHSRS 1339
Query: 2647 RSSAGERHGSHHQQSADSSRHSGIGHGQASSAVRDSGHRGYSGSQASDNEGHSEDSDTQS 2706
RS + S+ +S SR G + + + R S +R Y + S S + S
Sbjct: 1340 RSRSST--SSYRSRSYSRSRSRG-WYSRGRTRSRSSSYRSYKSHRTSSR----SRSRSSS 1392
Query: 2707 VSAHGQAGSHQQSHQESARGRSGETSGHSGSFLYQVSTHEQSESSHGWTGPSTRGRQGSR 2766
H ++ S+ S R RS S S S+ S + +S S + S R S
Sbjct: 1393 YDPHSRSRSYTYDSYYS-RSRSRSRSQRSDSYHRGRSYNRRSRSCRSYGSDSESDRSYSH 1451
Query: 2767 HEQAQDSSRHS 2777
H +SSR+S
Sbjct: 1452 HRSPSESSRYS 1462
Score = 102 bits (254), Expect = 8e-21
Identities = 264/1343 (19%), Positives = 465/1343 (34%), Gaps = 182/1343 (13%)
Query: 256 IYERSRS----SDGKSSSQVNRSRHENTSQVPLQESRTRKRRGSRV-----SQDRDSEGH 306
++E+ R S+G SS + S E++S+ L+ R+R+R+ R S+ R E
Sbjct: 184 VFEKKRKKPTHSEGSDSSSNSSSSSESSSESELEHERSRRRKHKRRPKVKRSKKRRKEAS 243
Query: 307 SED-------------SERHSGSASRNHHGSAWEQS-------------------RD--- 331
S + SER + R+ SA + RD
Sbjct: 244 SSEEPRNKHAMNPKGHSERSDTNEKRSVDSSAKREKPVVRPEEIPPVPENRFLLRRDMPV 303
Query: 332 --GSRHPRSHD------EDRASHGHSADSSRQSGTRHAETSSRGQTASSHEQARSSPGER 383
P+ D + + S S + GT T R ++ S + SS
Sbjct: 304 VTAEPEPKIPDVAPIVSDQKPSVSKSGRKIKGRGTIRYHTPPRSRSCSESDDDDSSETPP 363
Query: 384 HGSGHQQSADSSRHSATGRGQASSAVSDRGHRG------SSGSQASDSEGHSENSDTQSV 437
H Q + R + + +SD S S++ G+ + T
Sbjct: 364 HWKEEMQRLRAYRPPSGEKWSKGDKLSDPCSSRWDERSLSQRSRSWSYNGYYSDLSTARH 423
Query: 438 SGHGKAGLRQQSHQESTRGRSGERSGRSGSSLYQ-----------VSTHEQPDSAHGRTG 486
SGH K +++ + +G+ + R + + S+ + S+ R
Sbjct: 424 SGHHKKRRKEKKVKHKKKGKKQKHCRRHKQTKKRRILIPSDIESSKSSTRRMKSSCDRER 483
Query: 487 TSTGGRQGSHHEQARDSSRHSASQEGQDTIRGHPGSSRGGRQGSHHEQSVNR------SG 540
+S SHH RD S+ + T SSR + H QS +R +
Sbjct: 484 SSRSSSLSSHHSSKRDWSKSDKDVQSSLT-----HSSRDSYRSKSHSQSYSRGSSRSRTA 538
Query: 541 HSGSHHSHTTSQGRSDASHG------QSGSRSASRQTRNEEQSGDGTRHSGSRHHEASSQ 594
S HS + S+ RS + G +S ++AS+ + N+ + R + +++ Q
Sbjct: 539 SKSSSHSRSRSKSRSSSKSGHRKRASKSPRKTASQLSENKPVKTEPLRATMAQNENVVVQ 598
Query: 595 ------------ADSSRHSQVGQGQS----SGPRTSRNQGSSVSQDSDSQGHSEDSERWS 638
+DS S+ GQ S R + + +S + + +
Sbjct: 599 PVVAENIPVIPLSDSPPPSRWKPGQKPWKPSYERIQEMKAKTTHLLPIQSTYSLANIKET 658
Query: 639 GSASRNHHGSAQEQSRDGSRHPRSHHEDRAGHGHSADSSRKSGTRHTQNS--SSGQAASS 696
GS+S H +E++ + + S + DR+ SR S +R S S ASS
Sbjct: 659 GSSSSYHK---REKNSESDQSTYSKYSDRSSESSPRSRSRSSRSRSYSRSYTRSRSLASS 715
Query: 697 HEQARSSAGERHGSRHQLQSADSSRHSGTGHGQASSAVRDSGHRGSSGSQATDSEGHSED 756
H ++RS + H + SR S + R SSG + +S H +
Sbjct: 716 HSRSRSPSSRSHSRNKYSDHSQCSRSSSYTSISSDDGRRAKRRLRSSGKK--NSVSHKKH 773
Query: 757 SDTQSVSGHGQAGHHQQSHQESARDRSGERSRRSGSFLYQVSTHKQSESSHGWTGPSTGV 816
S + + H + + + S+ R SR S + + G
Sbjct: 774 SSSSEKTLHSK---YVKGRDRSSCVRKYSESRSSLDYSSDSEQSSVQATQSAQEKEKQGQ 830
Query: 817 RQGSHHEQARDNSRHSASQDGQDTIRGHPGSSRRGRQGSHHEQSVDRSGHSGSHHSHTTS 876
+ +H++Q ++ + + R P S +R + + + R+G ++ S
Sbjct: 831 MERTHNKQEKNRGEEKSKSE-----RECPHSKKRTLKENLSDHL--RNGSKPKRKNYAGS 883
Query: 877 QGRSDASRGQSGSRSASRTTRNEEQSRDGSRHSGSRHHEASSHADISRHSQAGQGQS--- 933
+ S+++ + ++++ + +G S S + H + +++ S
Sbjct: 884 KWDSESNSERDVTKNSKNDSHPSSDKEEGEATSDSESEVSEIHIKVKPTTKSSTNTSLPD 943
Query: 934 -EGSRTSRRQGSSVSQDSDSEGHSEDSERWSGSASRNHRGSAQEQSRHGSRHPRSHHEDR 992
G+ S +Q +S S DSEG +SE G ++ GS + R ++ + + +
Sbjct: 944 DNGAWKSSKQRTSTS---DSEGSCSNSENNRGKPQKHKHGSKENLKREHTKKVKEKLKGK 1000
Query: 993 AGHGHSADSSRQS--GTPHAETSSGGQAASSHEQARSSPGERHGSRHQQSADSSRHSGIP 1050
H A +Q+ P E + +Q E+ S + ++ + I
Sbjct: 1001 KDKKHKAPKRKQAFHWQPPLEFGEEEEEEIDDKQVTQESKEKKVSENNETIKDN----IL 1056
Query: 1051 RRQASSAVRDSGHWGSSGSQASDSEGHSEESDTQSVSGHGQDGPHQ-------QSHQESA 1103
+ + SS SG + + +SD + +++ S+S + Q +ES
Sbjct: 1057 KTEKSSEEDLSGKHDTV-TVSSDLDQFTKDDSKLSISPTALNTEENVACLQNIQHVEESV 1115
Query: 1104 RDWSGGRSGRSGSFIYQVSTHEQSESAHGRTRTSTGRRQGSHHEQARDSSRHSASQEGQD 1163
+ G ++ T ++S A + G AR + QD
Sbjct: 1116 PN--GVEDVLQTDDNMEICTPDRSSPAKVEETSPLGN--------ARLDTPDINIVLKQD 1165
Query: 1164 TIRAHPGSRRGGRQGSHHEQSVDRSGHSGSHHSHTTSQGRSDASHGQSGSRSASRQTRKD 1223
HP + ++ S E V G G S + S + S G+ S+ D
Sbjct: 1166 MATEHPQAEVVKQESSMSESKV--LGEVGKQDSSSASLASAGESTGKKEVAEKSQINLID 1223
Query: 1224 KQSG--DGSRHSGSRHHEAASWADSSRHSQVGQEQSSGSRTSRHQGSSVSQDS--DSERH 1279
K+ G + + + +S + + V + + G R + V S D R
Sbjct: 1224 KKWKPLQGVGNLAAPNAATSSAVEVKVLTTVPEMKPQGLRIEIKSKNKVRPGSLFDEVRK 1283
Query: 1280 SDDSERLSGSASRNHHGSSREQ--SRDGSRHPGFHQEDRASHGHSADSSRQSGTHHTESS 1337
+ R RN SS EQ SRD S S S H T S
Sbjct: 1284 TARLNR----RPRNQESSSDEQTPSRDDD-------SQSRSPSRSRSKSETKSRHRTRSV 1332
Query: 1338 SHGQAVSSHEQARSSPGERHGSRHQQSADSSRHSGIGHRQASSAVRDSGHRGSSGSQVTN 1397
S+ + S + SS R SR + SR G ++SS HR SS
Sbjct: 1333 SYSHSRSRSRSSTSSYRSRSYSRSRSRGWYSR--GRTRSRSSSYRSYKSHRTSS-----R 1385
Query: 1398 SEGHSEDSDTQSVSAHGQAGPHQQSHKESARGQSGESSGRSRSFLYQVSSHEQSESTHGQ 1457
S S D S S + + +R Q +S R RS+ + +S S
Sbjct: 1386 SRSRSSSYDPHSRSRSYTYDSYYSRSRSRSRSQRSDSYHRGRSY------NRRSRSCRSY 1439
Query: 1458 TAPSTGGRQGSRHEQARNSSRHS 1480
+ S R S H SSR+S
Sbjct: 1440 GSDSESDRSYSHHRSPSESSRYS 1462
Score = 101 bits (251), Expect = 2e-20
Identities = 259/1248 (20%), Positives = 430/1248 (34%), Gaps = 179/1248 (14%)
Query: 2820 TSQGRSDASRGQSGSRSASRTTRNEEQSGDGSRHSGSRHHEASTHADISRHSQAVQGQSE 2879
+ GR RG + R+ E D S + E Q ++
Sbjct: 327 SKSGRKIKGRGTIRYHTPPRSRSCSESDDDDSSETPPHWKE---------EMQRLRAYRP 377
Query: 2880 GSRRSRRQGSSVSQDSDSEGHSEDSERWSGSASRNHHGSAQEQLRDGSRHPRSHQEDRAG 2939
S +G +S S + S S S N + S R H + +E +
Sbjct: 378 PSGEKWSKGDKLSDPCSSRWDERSLSQRSRSWSYNGYYSDLSTARHSGHHKKRRKEKKVK 437
Query: 2940 HGHSADSSRQSGTRHTQTSSGGQAASSHEQARSSAGERHGSHHQQSADSSRHSGIGHGQA 2999
H + RH QT S ++ S+ R S S D R S
Sbjct: 438 HKKKGKKQKHC-RRHKQTKKRRILIPSDIESSKSSTRRMKS----SCDRERSS------R 486
Query: 3000 SSAVRDSGHRGYSGSQASDNEGHSEDSDTQSVSAHGQAGSHQ-QSHQESARGRSGETSGH 3058
SS++ S +S + D D QS H S++ +SH +S S +
Sbjct: 487 SSSL--------SSHHSSKRDWSKSDKDVQSSLTHSSRDSYRSKSHSQSYSRGSSRSRTA 538
Query: 3059 SGSFLYQVSTHEQSESSHGWTGPSTRGRQGSRHEQAQDSSRHSASQYGQDTIRGHPGSSR 3118
S S S+H +S S S + ++A S R +ASQ ++ P +
Sbjct: 539 SKS-----SSHSRSRSK------SRSSSKSGHRKRASKSPRKTASQLSENK----PVKTE 583
Query: 3119 GGRQGYHHEHSVDSSGHSGSHHSHTTSQGRSDASRGQSGSRS-----------ASRTTR- 3166
R +V + SR + G + ++TT
Sbjct: 584 PLRATMAQNENVVVQPVVAENIPVIPLSDSPPPSRWKPGQKPWKPSYERIQEMKAKTTHL 643
Query: 3167 ----------NEEQSGDSSRHSVSRHHEASTHADISRHSQAVQGQSEGSRRSRRQGSSVS 3216
N +++G SS + E ++ +D S +S+ SE S RSR S
Sbjct: 644 LPIQSTYSLANIKETGSSSSY---HKREKNSESDQSTYSKYSDRSSESSPRSR------S 694
Query: 3217 QDSDSEGHSEDSERWSGSASRNHRGSVQEQSRHGSRHPRSHHEDRAGHGHSADRSRQSGT 3276
+ S S +S R S S + +H S SR SR+ S H + S G
Sbjct: 695 RSSRSRSYSRSYTR-SRSLASSHSRSRSPSSRSHSRNKYSDHSQCSRSSSYTSISSDDGR 753
Query: 3277 RHAET--SSGGQAASSHEQARSSPGERHGSRHQQSADSSRHSGIPRGQ-ASSAVRDSRHW 3333
R SSG + + SH+ +H S++ + HS +G+ SS VR
Sbjct: 754 RAKRRLRSSGKKNSVSHK------------KHSSSSEKTLHSKYVKGRDRSSCVRKYSES 801
Query: 3334 GSSGSQASDSEGHSEESDTQSVSGHGQAGPHQQSHQESARDRSGGRSGRSGSFLYQVS-T 3392
SS +SDSE S ++ TQS + G +++H + ++R +S + T
Sbjct: 802 RSSLDYSSDSEQSSVQA-TQSAQEKEKQGQMERTHNKQEKNRGEEKSKSERECPHSKKRT 860
Query: 3393 HEQSESAHGRTRTSTGRRQ--GSHHEQARDSSRHSASQEGQDTIRGHPGSSRRGRQGSHY 3450
+++ S H R + R+ GS + +S R D+ HP S + + +
Sbjct: 861 LKENLSDHLRNGSKPKRKNYAGSKWDSESNSERDVTKNSKNDS---HPSSDKEEGEATSD 917
Query: 3451 EQSVDRSGH----SGSHHSHTTSQGRSDASRGQSGSRSASRQTRNDEQSGDGSRHSWSHH 3506
+S H + S TS + + S R+++ + + + +R H
Sbjct: 918 SESEVSEIHIKVKPTTKSSTNTSLPDDNGAWKSSKQRTSTSDSEGSCSNSENNRGKPQKH 977
Query: 3507 HEASTQADSSRHSQSGQGQSAGPRTSRNQG-------------------------SSVSQ 3541
S + H++ + + G + +++ V+Q
Sbjct: 978 KHGSKENLKREHTKKVKEKLKGKKDKKHKAPKRKQAFHWQPPLEFGEEEEEEIDDKQVTQ 1037
Query: 3542 DSDSQGHSEDSERWSGSASRNHRGSAQEQSRDGSRHPTSHHEDRAGHGHSAESSRQSGTH 3601
+S + SE++E + + + S ++ S S D+ S S + +
Sbjct: 1038 ESKEKKVSENNETIKDNILKTEKSSEEDLSGKHDTVTVSSDLDQFTKDDSKLSISPTALN 1097
Query: 3602 HAENSSGGQAASSHEQARSSAGERHGSHHQQSADSSRHSGIGHGQASSAVRDSGHRGSSG 3661
EN + Q E++ + G D + + + V ++ G++
Sbjct: 1098 TEENVACLQNIQHVEESVPN-----GVEDVLQTDDNMEICTPDRSSPAKVEETSPLGNA- 1151
Query: 3662 SQASDSEGHSEDSDTQSVSAHGQAGPHQQSH---QESTRGRSAGRSGRSGSFLYQVSTHE 3718
+ D V A H Q+ QES+ S L +V +
Sbjct: 1152 --------RLDTPDINIVLKQDMATEHPQAEVVKQESSMSES--------KVLGEVGKQD 1195
Query: 3719 QSESAHGRAGPSTGGRQGSRHEQARDSSRHSASQEGQDTIRGHPGSRRGGRQGSYHEQSV 3778
S ++ AG STG ++ + Q + +G + P + +V
Sbjct: 1196 SSSASLASAGESTGKKEVAEKSQINLIDKKWKPLQGVGNLAA-PNAATSSAVEVKVLTTV 1254
Query: 3779 DRSGHSGSHHSHTTSQGRSDASHGQSGSRSA--SRETRNEEQSGDGSRHSGSRHHEASTQ 3836
G + S ++A +R RN+E S D + ++
Sbjct: 1255 PEMKPQGLRIEIKSKNKVRPGSLFDEVRKTARLNRRPRNQESSSD---------EQTPSR 1305
Query: 3837 ADSSRHSQSGQGESAGSRRSRRQGSSVSQD-SDSEAYPEDSERRSESASRNHHGSSREQS 3895
D S+ + S +SR + SVS S S + S RS S SR+ S S
Sbjct: 1306 DDDSQSRSPSRSRSKSETKSRHRTRSVSYSHSRSRSRSSTSSYRSRSYSRSR--SRGWYS 1363
Query: 3896 RDGSRHPGSSHRDTASHVQSSPVQSDSSTAKEHGHFSSLSQDSAYHSGIQSRGSPHSSSS 3955
R +R SS+R SH SS +S SS+ H S + DS Y+S +SR S S
Sbjct: 1364 RGRTRSRSSSYRSYKSHRTSSRSRSRSSSYDPHSRSRSYTYDS-YYSRSRSRSRSQRSDS 1422
Query: 3956 YHYQSEGTERQKGQSGLVWRHGSYGSADYDYGESGFRHSQHGSVSYNS 4003
YH R + SYGS ES +S H S S +S
Sbjct: 1423 YHRGRSYNRRSRSCR-------SYGSD----SESDRSYSHHRSPSESS 1459
Score = 96.7 bits (239), Expect = 4e-19
Identities = 225/1128 (19%), Positives = 404/1128 (35%), Gaps = 147/1128 (13%)
Query: 85 YYESTRKENLPISGHKHRKHSHHDKHEDNKQEENKENRKRPSSLERRNNRKGNKGRSKSP 144
+++ RKE K +K H +H+ K K PS +E + + +S
Sbjct: 426 HHKKRRKEKKVKHKKKGKKQKHCRRHKQTK----KRRILIPSDIE-SSKSSTRRMKSSCD 480
Query: 145 RETGGKRHESSSEKKERKGYSPTHREEEYGKNHHN-SSKKEKNKTENTRLGDNRKRLSER 203
RE + SS ++ +S + ++ + H + S + K+ +++ G +R R + +
Sbjct: 481 RERSSRSSSLSSHHSSKRDWSKSDKDVQSSLTHSSRDSYRSKSHSQSYSRGSSRSRTASK 540
Query: 204 LEEKEDNEEGVYDYENTGRMTQKWIQSGHIATYYTIQDEAYDTTDSLLEENKIY--ERSR 261
+ + ++ +SGH ++ T S L ENK E R
Sbjct: 541 SS----------SHSRSRSKSRSSSKSGHRKR----ASKSPRKTASQLSENKPVKTEPLR 586
Query: 262 SSDGKSSSQVNRS-RHENTSQVPLQESRTRKR-----RGSRVSQDRDSEGHSEDSE---- 311
++ ++ + V + EN +PL +S R + + S +R E ++ +
Sbjct: 587 ATMAQNENVVVQPVVAENIPVIPLSDSPPPSRWKPGQKPWKPSYERIQEMKAKTTHLLPI 646
Query: 312 ---------RHSGSASRNHHGSAWEQSRDGSRHPRSHDEDRASHGHSADSSRQSGTR-HA 361
+ +GS+S H E++ + + S DR+S SR S +R ++
Sbjct: 647 QSTYSLANIKETGSSSSYHKR---EKNSESDQSTYSKYSDRSSESSPRSRSRSSRSRSYS 703
Query: 362 ETSSRGQT-ASSHEQARSSPGERHG----SGHQQSADSSRHSATGRGQASSAVSDRGHRG 416
+ +R ++ ASSH ++RS H S H Q + SS +++ SS R R
Sbjct: 704 RSYTRSRSLASSHSRSRSPSSRSHSRNKYSDHSQCSRSSSYTS-----ISSDDGRRAKRR 758
Query: 417 SSGSQASDSEGHSENSDTQSVSGHGK--------AGLRQQSHQEST---RGRSGERSGRS 465
S +S H ++S + + H K + +R+ S S+ S + S ++
Sbjct: 759 LRSSGKKNSVSHKKHSSSSEKTLHSKYVKGRDRSSCVRKYSESRSSLDYSSDSEQSSVQA 818
Query: 466 GSSLYQVSTHEQPDSAHGRTGTSTGGRQGSHHEQARDSSRHSASQEGQDTIRGHPGSSRG 525
S + Q + H + + G + + S + + + D +R R
Sbjct: 819 TQSAQEKEKQGQMERTHNKQEKNRGEEKSKSERECPHSKKRTLKENLSDHLRNGSKPKRK 878
Query: 526 GRQGSHHEQSVNRSGHSGSHHSHTTSQGRSDASHGQSGSRSASRQTRNEEQSGDGTRHSG 585
GS + N S + +S S SD G++ S S S + + T+
Sbjct: 879 NYAGSKWDSESN-SERDVTKNSKNDSHPSSDKEEGEATSDSESEVSEIHIKVKPTTK--- 934
Query: 586 SRHHEASSQADSSRHSQVGQGQSSGPRTSRNQGSSVSQDSDSQGHSEDSERWSGSASRNH 645
S ++S G +SS RTS SDS+G +SE G ++
Sbjct: 935 -------SSTNTSLPDDNGAWKSSKQRTS---------TSDSEGSCSNSENNRGKPQKHK 978
Query: 646 HGSAQEQSRDGSRHPRSHHEDRAGHGHSADSSRKSGTRHTQNSSSGQAASSH---EQARS 702
HGS + R+ ++ + + + H A RK G+ +Q
Sbjct: 979 HGSKENLKREHTKKVKEKLKGKKDKKHKA-PKRKQAFHWQPPLEFGEEEEEEIDDKQVTQ 1037
Query: 703 SAGERHGSRHQLQSADSSRHSGTGHGQASSAVRDSGHRGSSGSQATDSEGHSEDSDTQSV 762
+ E+ S + D+ + + S D+ S Q T + S T
Sbjct: 1038 ESKEKKVSENNETIKDNILKTEKSSEEDLSGKHDTVTVSSDLDQFTKDDSKLSISPTALN 1097
Query: 763 SGHGQAGHHQQSHQESARDRSGERSRRSGSFLYQVSTHKQSESSHGWTGPSTGVRQGSHH 822
+ A H E + E ++ + + + S + V + S
Sbjct: 1098 TEENVACLQNIQHVEESVPNGVEDVLQTDDNMEICTPDRSSPAK---------VEETSPL 1148
Query: 823 EQARDNSRHSASQDGQDTIRGHPGSSRRGRQGSHHEQSVDRSGHSGSHHSHTTSQGRSDA 882
AR ++ QD HP + ++ S E V G G S + S +
Sbjct: 1149 GNARLDTPDINIVLKQDMATEHPQAEVVKQESSMSESKV--LGEVGKQDSSSASLASAGE 1206
Query: 883 SRGQSGSRSASRTTRNEEQSR--DGSRHSGSRHHEASSHADISRHSQAGQGQSEGSRTSR 940
S G+ S+ +++ + G + + + SS ++ + + + +G R
Sbjct: 1207 STGKKEVAEKSQINLIDKKWKPLQGVGNLAAPNAATSSAVEVKVLTTVPEMKPQGLRIEI 1266
Query: 941 RQGSSVSQDSDSEGHSEDSERWSGSASRNHRGSAQEQSRHGSRHPRSHHEDRAGHGHSAD 1000
+ + V GS R +A+ +R PR+ S D
Sbjct: 1267 KSKNKVR---------------PGSLFDEVRKTARL-----NRRPRNQESSSDEQTPSRD 1306
Query: 1001 SSRQSGTPHAETSSGGQAASSHEQARSSPGERHGSR---HQQSADSSRHSGIPRRQASSA 1057
QS +P S +++S RH +R + S SR S R S +
Sbjct: 1307 DDSQSRSP------------SRSRSKSETKSRHRTRSVSYSHSRSRSRSSTSSYRSRSYS 1354
Query: 1058 VRDSGHWGSSGSQASDSEGH----SEESDTQSVSGHGQDGPHQQSHQES-----ARDWSG 1108
S W S G S S + S + ++S S PH +S + +R S
Sbjct: 1355 RSRSRGWYSRGRTRSRSSSYRSYKSHRTSSRSRSRSSSYDPHSRSRSYTYDSYYSRSRSR 1414
Query: 1109 GRSGRSGSFIYQVSTHEQSESAHGRTRTSTGRRQGSHHEQARDSSRHS 1156
RS RS S+ S + +S S S R SHH +SSR+S
Sbjct: 1415 SRSQRSDSYHRGRSYNRRSRSCRSYGSDSESDRSYSHHRSPSESSRYS 1462
Score = 76.3 bits (186), Expect = 6e-13
Identities = 166/787 (21%), Positives = 281/787 (35%), Gaps = 97/787 (12%)
Query: 3224 HSEDSERWSGSASRNHRGSVQEQSRHGSRHPRSHHEDRAGHGHSADRSRQSGTRHAETSS 3283
HSE S+ S S+S + S E SR R H+ R + ++S R E SS
Sbjct: 194 HSEGSDSSSNSSSSSESSSESELEHERSR--RRKHKRRP-------KVKRSKKRRKEASS 244
Query: 3284 GGQAASSHEQARSSPGERHGSRHQQSADSS--RHSGIPRGQASSAVRDSRHWGSSGSQAS 3341
+ + H ER + ++S DSS R + R + V ++R
Sbjct: 245 SEEPRNKHAMNPKGHSERSDTNEKRSVDSSAKREKPVVRPEEIPPVPENRFLLRRDMPVV 304
Query: 3342 DSEGHSEESDTQSVSGHGQAGPHQQSHQESARDRSGGRSGRSGSFLYQVSTHEQSESAHG 3401
+E + D + S Q+ + +SG + G+ Y +S S
Sbjct: 305 TAEPEPKIPDVAPIV----------SDQKPSVSKSGRKIKGRGTIRYHTPPRSRSCSESD 354
Query: 3402 RTRTSTGRRQGSHHEQARDSSRHSASQEGQDTIRGH----PGSSR--------RGRQGSH 3449
+S H ++ R G+ +G P SSR R R S+
Sbjct: 355 DDDSS---ETPPHWKEEMQRLRAYRPPSGEKWSKGDKLSDPCSSRWDERSLSQRSRSWSY 411
Query: 3450 --YEQSVDRSGHSGSHHSHTTSQGRSDASRGQSGSRSAS-RQTR-------NDEQSGDGS 3499
Y + + HSG H + +G+ +QT+ +D +S S
Sbjct: 412 NGYYSDLSTARHSGHHKKRRKEKKVKHKKKGKKQKHCRRHKQTKKRRILIPSDIESSKSS 471
Query: 3500 --RHSWSHHHEASTQADS-SRHSQSGQGQSAGPRTSRNQGSSVSQDS-DSQGHSEDSERW 3555
R S E S+++ S S H S + S + ++ + S+DS S+ HS+ R
Sbjct: 472 TRRMKSSCDRERSSRSSSLSSHHSSKRDWSKSDKDVQSSLTHSSRDSYRSKSHSQSYSRG 531
Query: 3556 SGSASRNHRGSAQEQSRDGSRHPT-SHHEDRAGHGHSAESSRQSGTHH------------ 3602
S + + S+ +SR SR + S H RA +S+ S
Sbjct: 532 SSRSRTASKSSSHSRSRSKSRSSSKSGHRKRASKSPRKTASQLSENKPVKTEPLRATMAQ 591
Query: 3603 ----------AENSSGGQAASSHEQARSSAGER--HGSHHQQSADSSRHSGIGHGQASSA 3650
AEN + S +R G++ S+ + ++ + + Q++ +
Sbjct: 592 NENVVVQPVVAENIPVIPLSDSPPPSRWKPGQKPWKPSYERIQEMKAKTTHLLPIQSTYS 651
Query: 3651 VRDSGHRGSSGSQASDSEGHSEDSDTQSVSAHGQAGPHQQSHQESTRGRSAGRSGRSGSF 3710
+ + GSS S + D T S + + +S S+R RS RS
Sbjct: 652 LANIKETGSSSSYHKREKNSESDQSTYSKYSDRSSESSPRSRSRSSRSRSYSRSYTRSRS 711
Query: 3711 LYQVSTHEQSESAHGRAGPSTGGRQGSRHEQARDSSRHSASQEGQDTIRGHPGSRRGGRQ 3770
L S+H +S S R S + S H Q SS ++ S D R R G++
Sbjct: 712 L--ASSHSRSRSPSSR---SHSRNKYSDHSQCSRSSSYT-SISSDDGRRAKRRLRSSGKK 765
Query: 3771 GSYHEQSVDRSGHSGSHHSHTTSQGRSDASHGQSGSRSASRETRNEEQSGDGSRHSGSRH 3830
S SH H++S ++ S G R S R +S +S S
Sbjct: 766 NSV------------SHKKHSSSSEKTLHSKYVKG-RDRSSCVRKYSESRSSLDYS-SDS 811
Query: 3831 HEASTQADSSRHSQSGQGESAGSRRSRRQGSSVSQDSDSEAYPEDSERRSESASRNH--H 3888
++S QA S + QG+ + + + + P +R + +H +
Sbjct: 812 EQSSVQATQSAQEKEKQGQMERTHNKQEKNRGEEKSKSERECPHSKKRTLKENLSDHLRN 871
Query: 3889 GSSREQSRDGSRHPGSSHRDTASHVQSSPVQSDSSTAKEHGHFSSLSQDSAYHSGIQSRG 3948
GS ++ S ++S S S+ KE G +S S+ I+ +
Sbjct: 872 GSKPKRKNYAGSKWDSESNSERDVTKNSKNDSHPSSDKEEGEATSDSESEVSEIHIKVKP 931
Query: 3949 SPHSSSS 3955
+ SS++
Sbjct: 932 TTKSSTN 938
Score = 51.2 bits (121), Expect = 2e-05
Identities = 56/181 (30%), Positives = 85/181 (46%), Gaps = 22/181 (12%)
Query: 3530 RTSRNQGSSVSQDSDSQGHSEDSERWSGSASRNHRGSAQEQSRDGSRHPT-SHHEDRAGH 3588
R RNQ SS SD Q S D + S S SR+ R ++ +SR +R + SH R+
Sbjct: 1289 RRPRNQESS----SDEQTPSRDDDSQSRSPSRS-RSKSETKSRHRTRSVSYSHSRSRSRS 1343
Query: 3589 GHSAESSRQSGTHHAENSSGGQAASSHEQARSSAGERHGSHHQQSADSSRHSGIG-HGQA 3647
S+ SR ++ + S G + ++RSS+ + SH S SR S H ++
Sbjct: 1344 STSSYRSRS----YSRSRSRGWYSRGRTRSRSSSYRSYKSHRTSSRSRSRSSSYDPHSRS 1399
Query: 3648 SSAVRDSGH---RGSSGSQASDS--EGHSEDSDTQSVSAHG------QAGPHQQSHQEST 3696
S DS + R S SQ SDS G S + ++S ++G ++ H +S ES+
Sbjct: 1400 RSYTYDSYYSRSRSRSRSQRSDSYHRGRSYNRRSRSCRSYGSDSESDRSYSHHRSPSESS 1459
Query: 3697 R 3697
R
Sbjct: 1460 R 1460
Score = 50.1 bits (118), Expect = 5e-05
Identities = 89/406 (21%), Positives = 136/406 (33%), Gaps = 60/406 (14%)
Query: 3593 ESSRQSGTHHAENSSGGQAASSHEQARSSAGERHGSHHQQSADSSRHSGIGHGQASSAVR 3652
E R+ TH + S ++SS E + S E S ++ H + R
Sbjct: 186 EKKRKKPTHSEGSDSSSNSSSSSESSSESELEHERSRRRK-----------HKRRPKVKR 234
Query: 3653 DSGHRGSSGSQ-------ASDSEGHSEDSDTQSVSAHGQAGPHQQSHQESTRGRSAGRSG 3705
R + S A + +GHSE SDT + + ++ +
Sbjct: 235 SKKRRKEASSSEEPRNKHAMNPKGHSERSDTNEKRSVDSSAKREKPVVRPEEIPPVPEN- 293
Query: 3706 RSGSFLYQVSTHEQSESAHGRAGPSTGGRQGSRHEQARDSSRHSASQEGQDTIRGHPGSR 3765
FL + P +Q S+ +G+ TIR H R
Sbjct: 294 ---RFLLR----RDMPVVTAEPEPKIPDVAPIVSDQKPSVSKSGRKIKGRGTIRYHTPPR 346
Query: 3766 RGGRQGSYHEQSVDRSGH------------SGSHHSHTTSQGRSDASHGQSGSRSASRET 3813
S + S + H S + SD + RS S+ +
Sbjct: 347 SRSCSESDDDDSSETPPHWKEEMQRLRAYRPPSGEKWSKGDKLSDPCSSRWDERSLSQRS 406
Query: 3814 RNEEQSG-----DGSRHSGSRHHEASTQADSSRHSQSGQGESAGSRRSRRQGSSVSQDSD 3868
R+ +G +RHSG HH+ + +H + G+ + R + + + SD
Sbjct: 407 RSWSYNGYYSDLSTARHSG--HHKKRRKEKKVKHKKKGKKQKHCRRHKQTKKRRILIPSD 464
Query: 3869 SEAYPEDSERRSESASRNHHGSSREQSRDGSRHPGSSHRDTASH---VQSSPVQSDSSTA 3925
E+ + R S R SSR S S H SS RD + VQSS S +
Sbjct: 465 IESSKSSTRRMKSSCDRER--SSRSSSLS-SHH--SSKRDWSKSDKDVQSSLTHSSRDSY 519
Query: 3926 KEHGHFSSLSQDSAYHSGIQSRGSPHSSSSYHYQSEGTERQKGQSG 3971
+ H S S+ S SR S SS H +S R +SG
Sbjct: 520 RSKSHSQSYSRGS-------SRSRTASKSSSHSRSRSKSRSSSKSG 558
Score = 40.8 bits (94), Expect = 0.028
Identities = 44/177 (24%), Positives = 67/177 (37%), Gaps = 11/177 (6%)
Query: 3657 RGSSGSQASDSEGHSEDSDTQSVSAHGQAGPHQQSHQESTRGRSAGRS---GRSGSFLYQ 3713
R + +SD + S D D+QS S + + TR S S RS + Y+
Sbjct: 1290 RPRNQESSSDEQTPSRDDDSQSRSPSRSRSKSETKSRHRTRSVSYSHSRSRSRSSTSSYR 1349
Query: 3714 VSTHEQSESAHGRAGPSTGGRQGSRHEQARDSSRHSASQEGQDTIRGH-PGSR-RGGRQG 3771
++ +S S G + GR SR R H S + + P SR R
Sbjct: 1350 SRSYSRSRSR----GWYSRGRTRSRSSSYRSYKSHRTSSRSRSRSSSYDPHSRSRSYTYD 1405
Query: 3772 SYHEQSVDRSG--HSGSHHSHTTSQGRSDASHGQSGSRSASRETRNEEQSGDGSRHS 3826
SY+ +S RS S S+H + RS + + R + + SR+S
Sbjct: 1406 SYYSRSRSRSRSQRSDSYHRGRSYNRRSRSCRSYGSDSESDRSYSHHRSPSESSRYS 1462
>gi|239508976 PREDICTED: mucin 12, cell surface associated [Homo
sapiens]
Length = 2036
Score = 114 bits (285), Expect = 2e-24
Identities = 338/1515 (22%), Positives = 510/1515 (33%), Gaps = 216/1515 (14%)
Query: 2567 FSQDSDSQGHSEDSERWSGSASRNHHGSAQEQLRDGSRHPRSHQE-DRAGHGHSADSSRQ 2625
F + S + GHSE+S + GS + H S+ H H H DSS
Sbjct: 3 FPESSTTSGHSEESATFHGSTT--HTKSSTPSTTAALAHTSYHSSLGSTETTHFRDSSTI 60
Query: 2626 SGTRHTQTSSGGQAASSHEQARSSAGERHGSHHQQSADSSRHSGIGHGQASSAVRDSGHR 2685
SG S +A+ S A ++ GS S S I G +
Sbjct: 61 SG-----RSEESKASHSSPDAMATTVLPAGSTPSVLVGDSTPSPISSGSMETTALPG--- 112
Query: 2686 GYSGSQASDNEGHSEDSDTQSVSAHGQAGSHQQSHQESARGRSGETSGHSGSFLYQVSTH 2745
++ G SE S T S +H + S+ G S E++ ++H
Sbjct: 113 ------STTKPGLSEKSTTFYSSPRSPDTTHLPASMTSS-GVSEEST----------TSH 155
Query: 2746 EQSESSHGWTGPSTRGRQGSRHEQAQDSSRHSASQDGQDTIRGHPGSSRGGRQG--YHHE 2803
+ S+H P + G +Q+S+ +S DT PGS+ G Y
Sbjct: 156 SRPGSTHTTAFPGSTTMPG----LSQESTASHSSPGPTDTTLS-PGSTTASSLGPEYTTF 210
Query: 2804 HSVDSSGHSGSHHSHTTSQGRSDASRGQSGSRSASRTTRNEEQSGDGSRHSGSRHHEAST 2863
HS S + +TT+ G +AS S + TT + S S + H S+
Sbjct: 211 HSRPGSTETTLLPDNTTASGLLEASMPVHSSTRSPHTTLSPAGSTTRQGESTTFHSWPSS 270
Query: 2864 HADISRHSQAVQGQSEGSRRSRRQGSS-----VSQDSDSEGHSEDSERW---SGSASRNH 2915
E S S SS +S S + G E+S + GS H
Sbjct: 271 KDTRPAPPTTTSAFVEPSTTSHGSPSSIPTTHISARSTTSGLVEESTTYHSSPGSTQTMH 330
Query: 2916 HGSAQEQLRDGSRHPRSHQEDRAGHGHSADSSRQSGTRHTQT---SSGGQAASSHEQARS 2972
+ G SH H S+ S S T SS G A++H S
Sbjct: 331 FPESDTTSGRGEESTTSHSS--TTHTISSAPSTTSALVEEPTSYHSSPGSTATTHFPDSS 388
Query: 2973 SAG----ERHGSHHQQSADSS------RHSGIGHGQASSAVRDSGHRGYSGSQAS-DNEG 3021
+ E SH Q A + + + G+++++ SG + S G
Sbjct: 389 TTSGRSEESTASHSSQDATGTIVLPARSTTSVLLGESTTSPISSGSMETTALPGSTTTPG 448
Query: 3022 HSEDSDTQSVSAHGQAGSHQQS-------HQESARGRSGETSGHSGSFLYQVST------ 3068
SE S T S A + + +ES RS S H+ +F +T
Sbjct: 449 LSERSTTFHSSPRSPATTLSPASTTSSGVSEESTTSRSRPGSTHTTAFPDSTTTPGLSRH 508
Query: 3069 HEQSESSHGWTGPSTRGRQGSRHEQAQDSSRHSASQYGQDTIRGHPGSSRGGRQGYHHE- 3127
S SS G T + + +Q+S+ +S DT PGS+ G
Sbjct: 509 STTSHSSPGSTDTTLLPASTTTSGPSQESTTSHSSSGSTDTALS-PGSTTALSFGQESTT 567
Query: 3128 -HSVDSSGHSGSHHSHTTSQGRSDASRGQSGSRSASRTTRNEEQS---GDSSRHSVSRHH 3183
HS S H+ TTS G +AS S + RTT + S G + + H
Sbjct: 568 FHSNPGSTHTTLFPDSTTSSGIVEASTRVHSSTGSPRTTLSPASSTSPGLQGESTAFQTH 627
Query: 3184 EASTHADISRHSQAVQGQSEGSRRSRRQGSSVS----QDSDSEGHSEDSERWSGSASRNH 3239
ASTH S S A E + R GS+ + S + GHSE S + S +
Sbjct: 628 PASTHTTPSPPSTATAPVEESTTYHRSPGSTPTTHFPASSTTSGHSEKSTIFHSSPDAS- 686
Query: 3240 RGSVQEQSRHGSRHPRSHHEDRAGHGHSADRSRQSGTRHAETSSGGQAASSHEQARSSPG 3299
P S H +G G S G+ T G + ++PG
Sbjct: 687 -----------GTTPSSAHSTTSGRGESTTSRISPGSTEITTLPG---------STTTPG 726
Query: 3300 ERHGSRHQQSADSSRHSGIPRGQASSAVRDSRHWGSSGSQASDSEGHSEESDTQSVSGHG 3359
S S+ S P S A S G S S +Q S H
Sbjct: 727 LSEASTTFYSSPRS-----PTTTLSPASMTSLGVGE----------ESTTSRSQPGSTHS 771
Query: 3360 QAGPHQQSHQESARDRSGGRSGRSGSFLYQVSTHEQSESAHGRTRTSTGRRQGSHHEQA- 3418
P + + + + S GS V H + S HG T+ R S H
Sbjct: 772 TVSPASTTTPGLSEESTTVYSSSRGSTETTVFPHSTTTSVHGEEPTTFHSRPASTHTTLF 831
Query: 3419 RDSSRHSASQEGQDTIRGHPGSSRRGRQGSHYEQSVDRSGHSGSHHSHTTSQGRSDASRG 3478
+ S S E G P S++ G + + + S +T S A
Sbjct: 832 TEDSTTSGLTEESTAFPGSPASTQTGLPATLTTADLGEESTTFPSSSGSTGTKLSPARST 891
Query: 3479 QSGSRSASRQTRNDEQSGD-----GSRHSWSHHHEASTQADSSRHSQSGQGQSAGPRTSR 3533
SG S +R S + GS + S +++T S R + + P T+
Sbjct: 892 TSGLVGESTPSRLSPSSTETTTLPGSPTTPSLSEKSTTFYTSPRSPDA----TLSPATTT 947
Query: 3534 NQG-SSVSQDSDSQGHSEDSERWSGSASRNHRGSAQEQSRDGSRHPTSHHEDRA------ 3586
+ G S S S SQ S + + S + + D S+ PT+ H +
Sbjct: 948 SSGVSEESSTSHSQPGSTHTTAFPDSTT----------TSDLSQEPTTSHSSQGSTEATL 997
Query: 3587 --GHGHSAESSRQSGTHHAENSSGGQAASSHEQARSSAGERHGSHHQQSADSSRHSGIGH 3644
G ++ +QS T H +S G + ++G S S+ S H+ +
Sbjct: 998 SPGSTTASSLGQQSTTFH--SSPGDTETTLLPDDTITSGLVEASTPTHSSTGSLHTTLTP 1055
Query: 3645 GQASSA-VRDSGHRGSSGSQASDSEG----------------HSEDSDTQSVSAHGQAGP 3687
++SA +++ S +SD+ HS S T + +
Sbjct: 1056 ASSTSAGLQEESTTFQSWPSSSDTTPSPPGTTAAPVEVSTTYHSRPSSTPTTHFSASSTT 1115
Query: 3688 HQQSHQESTRGRSAGRSG------RSGSFLYQVSTHEQSESAHGRAGPSTGGRQGSRHE- 3740
+S + +T S G +G RS + V E + S T GS
Sbjct: 1116 LGRSEESTTVHSSPGATGTALFPTRSAT---SVLVGEPTTSPISSGSTETTALPGSTTTA 1172
Query: 3741 --QARDSSRHSASQEGQDTIRGHPGSRRGGRQGSYHEQSVDRSGHSGSHHSHTTSQG--- 3795
+ ++ +S+ + T+ + G + S S S H+ + TT G
Sbjct: 1173 GLSEKSTTFYSSPRSPDTTLSPASTTSSGVSEESTTSHSRPGSTHTTAFPGSTTMPGVSQ 1232
Query: 3796 RSDASHGQSGSRSASRETRNEEQSGDGSR----HS---------------GSRHHEASTQ 3836
S ASH GS + + S G HS S EAST
Sbjct: 1233 ESTASHSSPGSTDTTLSPGSTTASSLGPESTTFHSSPGSTETTLLPDNTTASGLLEASTP 1292
Query: 3837 ADSSRHSQSGQGESAGSRRSRRQGSSVSQDS-----DSEAYPEDSERRSESASRNHHG-- 3889
SS S AGS + RQG S + S D+ P + S HG
Sbjct: 1293 VHSSTGSPHTTLSPAGS--TTRQGESTTFQSWPSSKDTMPAPPTTTSAFVELSTTSHGSP 1350
Query: 3890 SSREQSRDGSRHPGSSHRDTASHVQSSPVQSDSSTAKEHGHFSSLSQDS-AYHSGIQSRG 3948
SS + + + ++ V SSPV + ++ + S L ++S AYHS
Sbjct: 1351 SSTPTTHFSASSTTLGRSEESTTVHSSPVATATTPSPARSTTSGLVEESTAYHS------ 1404
Query: 3949 SPHSSSSYHYQSEGT 3963
SP S+ + H+ T
Sbjct: 1405 SPGSTQTMHFPESST 1419
Score = 110 bits (275), Expect = 3e-23
Identities = 334/1553 (21%), Positives = 511/1553 (32%), Gaps = 189/1553 (12%)
Query: 2287 EDRAGHGHSAESSRQSG--THHAENSSGGQAASSHEQARSSAGERHGSHHQQSADSSRHS 2344
E GHS ES+ G TH ++ AA +H SS G +H + S+ S S
Sbjct: 5 ESSTTSGHSEESATFHGSTTHTKSSTPSTTAALAHTSYHSSLGSTETTHFRDSSTISGRS 64
Query: 2345 GIGHGQASSAVRDSGHRGSSGSQASDSEGHSEDSDTQSVSAHGQAGPHQQSHQESTRGRS 2404
SS + +GS S G S S S S A P +
Sbjct: 65 EESKASHSSPDAMATTVLPAGSTPSVLVGDSTPSPISSGSMETTALPGSTT--------K 116
Query: 2405 AGRSGRSGSFLYQVSTHEQSESAH-GRTGTSTGGRQGSHHKQARDSSRHSTSQEGQDTIH 2463
G S +S +F S+ ++ H + TS+G + S +R S H+T+ G T+
Sbjct: 117 PGLSEKSTTF---YSSPRSPDTTHLPASMTSSGVSEESTTSHSRPGSTHTTAFPGSTTMP 173
Query: 2464 G-------------------HPGSSSGGRQGSHYEQLVDRSGHSGSH--HSHTTSQGRSD 2502
G PGS++ G Y R G + + +TT+ G +
Sbjct: 174 GLSQESTASHSSPGPTDTTLSPGSTTASSLGPEYTTFHSRPGSTETTLLPDNTTASGLLE 233
Query: 2503 ASHGHSGSRSASRQTRNDEQSGDGSRHSGSRHHEASSRADSSGHSQVGQGQSEGPRTSRN 2562
AS S + T + S S + H SS+ E TS
Sbjct: 234 ASMPVHSSTRSPHTTLSPAGSTTRQGESTTFHSWPSSKDTRPAPPTTTSAFVEPSTTSHG 293
Query: 2563 WGSS-----FSQDSDSQGHSEDSERW---SGSASRNHHGSAQEQLRDGSRHPRSHQEDRA 2614
SS S S + G E+S + GS H + G SH
Sbjct: 294 SPSSIPTTHISARSTTSGLVEESTTYHSSPGSTQTMHFPESDTTSGRGEESTTSHSS--T 351
Query: 2615 GHGHSADSSRQSGTRHTQT---SSGGQAASSHEQARSSAG----ERHGSHHQQSADSS-- 2665
H S+ S S T SS G A++H S+ E SH Q A +
Sbjct: 352 THTISSAPSTTSALVEEPTSYHSSPGSTATTHFPDSSTTSGRSEESTASHSSQDATGTIV 411
Query: 2666 ----RHSGIGHGQASSAVRDSGHRGYSGSQAS-DNEGHSEDSDTQSVSAHGQAGSHQQS- 2719
+ + G+++++ SG + S G SE S T S A + +
Sbjct: 412 LPARSTTSVLLGESTTSPISSGSMETTALPGSTTTPGLSERSTTFHSSPRSPATTLSPAS 471
Query: 2720 ------HQESARGRSGETSGHSGSFLYQVST------HEQSESSHGWTGPSTRGRQGSRH 2767
+ES RS S H+ +F +T S SS G T + +
Sbjct: 472 TTSSGVSEESTTSRSRPGSTHTTAFPDSTTTPGLSRHSTTSHSSPGSTDTTLLPASTTTS 531
Query: 2768 EQAQDSSRHSASQDGQDTIRGHPGSSRGGRQGYHHE--HSVDSSGHSGSHHSHTTSQGRS 2825
+Q+S+ +S DT PGS+ G HS S H+ TTS G
Sbjct: 532 GPSQESTTSHSSSGSTDTALS-PGSTTALSFGQESTTFHSNPGSTHTTLFPDSTTSSGIV 590
Query: 2826 DASRGQSGSRSASRTTRNEEQS---GDGSRHSGSRHHEASTHADISRHSQAVQGQSEGSR 2882
+AS S + RTT + S G + + H ASTH S S A E +
Sbjct: 591 EASTRVHSSTGSPRTTLSPASSTSPGLQGESTAFQTHPASTHTTPSPPSTATAPVEESTT 650
Query: 2883 RSRRQGSSVS----QDSDSEGHSEDSERWSGSASRNHHGSAQEQLRDGSRHPRSHQEDRA 2938
R GS+ + S + GHSE S + S + P S +
Sbjct: 651 YHRSPGSTPTTHFPASSTTSGHSEKSTIFHSSPDAS------------GTTPSSAHSTTS 698
Query: 2939 GHGHSADSSRQSGTRHTQTSSGGQAASSHEQARSSAGERHGSHHQQSADSSRHS-GIGHG 2997
G G S S G+ T G +A ++ S + +S S G+G
Sbjct: 699 GRGESTTSRISPGSTEITTLPGSTTTPGLSEASTTFYSSPRSPTTTLSPASMTSLGVGEE 758
Query: 2998 QASSAVRDSGHRGYSGSQASDNEGHSEDSDTQSVSAHGQAGSHQQSHQESARGRSGE-TS 3056
+S + ++ G SE+S T S+ G + H + E T+
Sbjct: 759 STTSRSQPGSTHSTVSPASTTTPGLSEESTTVYSSSRGSTETTVFPHSTTTSVHGEEPTT 818
Query: 3057 GHSGSFLYQVSTHEQSESSHGWTGPSTRGRQGSRHEQAQDSSRHSASQYGQDTIRGHPGS 3116
HS + + ++ G T ST Q + + + G+++ P S
Sbjct: 819 FHSRPASTHTTLFTEDSTTSGLTEESTAFPGSPASTQTGLPATLTTADLGEESTT-FPSS 877
Query: 3117 SRGGRQGYHHEHSVDSSGHSGSHHSHTTS--QGRSDASRGQSGSRSASRTTRNEEQSGDS 3174
S S+G S TTS G S SR S + + S
Sbjct: 878 S-------------GSTGTKLSPARSTTSGLVGESTPSRLSPSSTETTTLPGSPTTPSLS 924
Query: 3175 SRHSVSRHHEASTHADISRHSQAVQGQSEGSRRSRRQGSSVSQDSDSEGHSEDSERWSGS 3234
+ + S A +S + G SE S S Q S + + + +
Sbjct: 925 EKSTTFYTSPRSPDATLSPATTTSSGVSEESSTSHSQPGSTHTTAFPDSTTTSDLSQEPT 984
Query: 3235 ASRNHRGSVQEQSRHGSRHPRSHHEDRAGHGHS---------ADRSRQSGTRHAETSSGG 3285
S + +GS + GS S + S D + SG A T +
Sbjct: 985 TSHSSQGSTEATLSPGSTTASSLGQQSTTFHSSPGDTETTLLPDDTITSGLVEASTPTHS 1044
Query: 3286 QAASSH-----EQARSSPGERHGSRHQQSADSSRHSGIPRGQASSAVRDSRHWGSSGSQ- 3339
S H + S+ + + Q SS + P G ++ V S + S S
Sbjct: 1045 STGSLHTTLTPASSTSAGLQEESTTFQSWPSSSDTTPSPPGTTAAPVEVSTTYHSRPSST 1104
Query: 3340 -------ASDSEGHSEESDTQSVS-------------------GHGQAGPHQQSHQES-- 3371
+S + G SEES T S G P E+
Sbjct: 1105 PTTHFSASSTTLGRSEESTTVHSSPGATGTALFPTRSATSVLVGEPTTSPISSGSTETTA 1164
Query: 3372 --ARDRSGGRSGRSGSFLYQVSTHEQSESAHGRTRTSTGRRQGSHHEQARDSSRHSASQE 3429
+ G S +S +F S + + TS+G + S +R S H+ +
Sbjct: 1165 LPGSTTTAGLSEKSTTF--YSSPRSPDTTLSPASTTSSGVSEESTTSHSRPGSTHTTAFP 1222
Query: 3430 GQDTIRGHPGSSRRGRQGSHYEQSVDRSGHSGSHHSHTTSQGRSDASRGQSGSRSASRQT 3489
G T+ PG S+ S D + GS + + S GS +
Sbjct: 1223 GSTTM---PGVSQESTASHSSPGSTDTTLSPGSTTASSLGP-ESTTFHSSPGSTETTLLP 1278
Query: 3490 RNDEQSG-----------DGSRH-SWSHHHEASTQADSSRHSQSGQGQSAGPRTSRNQGS 3537
N SG GS H + S + Q +S+ + P +
Sbjct: 1279 DNTTASGLLEASTPVHSSTGSPHTTLSPAGSTTRQGESTTFQSWPSSKDTMPAPPTTTSA 1338
Query: 3538 SVSQDSDSQGHSEDSERWSGSASRNHRGSAQEQSRDGSRHPTSHHEDRAGHGHSAESSRQ 3597
V + S G + SAS G ++E + S + ++ +
Sbjct: 1339 FVELSTTSHGSPSSTPTTHFSASSTTLGRSEESTTVHSSPVATATTPSPARSTTSGLVEE 1398
Query: 3598 SGTHHAENSSGGQAASSHEQARSSAGERHGSHHQQSADSSRHSGIGHGQASSAV--RDSG 3655
S +H SS G + H S+A R + S S+ H+ +SA+ +
Sbjct: 1399 STAYH---SSPGSTQTMHFPESSTASGR-SEESRTSHSSTTHTISSPPSTTSALVEEPTS 1454
Query: 3656 HRGSSGS-------QASDSEGHSEDSDTQSVSAHGQAGPHQQSHQESTRGRSA 3701
+ S GS ++S + G SE+S T S S+ G +T GR A
Sbjct: 1455 YHSSPGSIATTHFPESSTTSGRSEES-TASHSSPDTNGITPLPAHFTTSGRIA 1506
Score = 99.0 bits (245), Expect = 9e-20
Identities = 339/1602 (21%), Positives = 541/1602 (33%), Gaps = 211/1602 (13%)
Query: 623 QDSDSQGHSEDSERWSGSASRNHHGSAQEQSRDGSRHPRSHHEDRAG--HGHSADSSRKS 680
+ S + GHSE+S + GS + H + S + S+H H DSS S
Sbjct: 5 ESSTTSGHSEESATFHGSTT---HTKSSTPSTTAALAHTSYHSSLGSTETTHFRDSSTIS 61
Query: 681 GTRHTQNSSSGQAASSHEQARSSAGERHGSRHQLQSADSSRHSGTGHGQASSAVRDSGHR 740
G S +A+ S A ++ GS + DS+ + ++A+ S
Sbjct: 62 G-----RSEESKASHSSPDAMATTVLPAGSTPSVLVGDSTPSPISSGSMETTALPGS--- 113
Query: 741 GSSGSQATDSEGHSEDSDTQSVSGHGQAGHHQQSHQESARDRSGERSRRSGSFLYQVSTH 800
T G SE S T S H + S SG ++H
Sbjct: 114 -------TTKPGLSEKSTTFYSSPRSPDTTHLPASMTS-----------SGVSEESTTSH 155
Query: 801 KQSESSHGWTGPSTGVRQGSHHEQARDNSRHSASQDGQDTIRGHPGSSRRGRQGSHHEQS 860
+ S+H P + G E S S S G PGS+ G +
Sbjct: 156 SRPGSTHTTAFPGSTTMPGLSQE-----STASHSSPGPTDTTLSPGSTTASSLGPEYTTF 210
Query: 861 VDRSGHSGSH--HSHTTSQGRSDASRGQSGSRSASRTTRNEEQSRDGSRHSGSRHHEASS 918
R G + + +TT+ G +AS S + TT + S S + H SS
Sbjct: 211 HSRPGSTETTLLPDNTTASGLLEASMPVHSSTRSPHTTLSPAGSTTRQGESTTFHSWPSS 270
Query: 919 HADISRHSQAGQGQSEGSRTSRRQGSS-----VSQDSDSEGHSEDSERWSGSASRNHRGS 973
E S TS SS +S S + G E+S + H
Sbjct: 271 KDTRPAPPTTTSAFVEPSTTSHGSPSSIPTTHISARSTTSGLVEESTTY-------HSSP 323
Query: 974 AQEQSRHGSRHPRSHHEDRAGHGHSADSSRQSGTPHAETSSGGQAASSHEQARSSPGERH 1033
Q+ H P S + +G G + +S S T H +S+ ++ E+ S
Sbjct: 324 GSTQTMH---FPES--DTTSGRGEESTTS-HSSTTHTISSAPSTTSALVEEPTSYHSSPG 377
Query: 1034 GSRHQQSADSSRHSGIPRRQASSAVRDSGHWGSSGSQASDSEGHSEESDTQSVSGHGQDG 1093
+ DSS SG R + S+A S A+ + S T + G
Sbjct: 378 STATTHFPDSSTTSG--RSEESTA-------SHSSQDATGTIVLPARSTTSVLLGESTTS 428
Query: 1094 PHQQSHQES----ARDWSGGRSGRSGSFIYQVSTHEQSESAHGRTRTSTGRRQGSHHEQA 1149
P E+ + G S RS +F S + + + TS+G + S ++
Sbjct: 429 PISSGSMETTALPGSTTTPGLSERSTTF--HSSPRSPATTLSPASTTSSGVSEESTTSRS 486
Query: 1150 RDSSRHSASQEGQDTIRAHPGSRRGGRQGSHHEQSVDRSGHSGSHHSHTTSQGRSDASHG 1209
R S H+ + T PG R HS + HS S G +D +
Sbjct: 487 RPGSTHTTAFPDSTTT---PGLSR----------------HSTTSHS---SPGSTDTT-- 522
Query: 1210 QSGSRSASRQTRKDKQSGDGSRHSGSRHHEAASWADSSRHSQVGQEQSSGSRTSRHQGSS 1269
AS T Q S HS S + A S+ GQE ++ ++
Sbjct: 523 ---LLPASTTTSGPSQESTTS-HSSSGSTDTALSPGSTTALSFGQESTTFHSNPGSTHTT 578
Query: 1270 VSQDSDSERHSDDSERLSGSASRNHH--GSSREQ-SRDGSRHPGFHQEDRASHGHSADSS 1326
+ DS + S + +++R H GS R S S PG E A H A +
Sbjct: 579 LFPDSTT------SSGIVEASTRVHSSTGSPRTTLSPASSTSPGLQGESTAFQTHPASTH 632
Query: 1327 RQSGTHHTESSSHGQAVSSHEQARSSPGERHGSRHQQSADSSRHSGIGHRQASSAVRDSG 1386
T ++ ++ + H S+P H ++ S S I H S+ SG
Sbjct: 633 TTPSPPSTATAPVEESTTYHRSPGSTP-TTHFPASSTTSGHSEKSTIFH----SSPDASG 687
Query: 1387 HRGSSGSQVTNSEGHSEDS-----DTQSVSAHGQAGPHQQSHKESARGQSGESSGRSRSF 1441
SS T+ G S S T+ + G S + S S + S
Sbjct: 688 TTPSSAHSTTSGRGESTTSRISPGSTEITTLPGSTTTPGLSEASTTFYSSPRSPTTTLSP 747
Query: 1442 LYQVSSHEQSESTHGQTAPSTGGRQGSRHEQARNSSRHSASQDGQDTIRGHPGSSRGGRQ 1501
S EST ++ P GS H +S + + T SSRG +
Sbjct: 748 ASMTSLGVGEESTTSRSQP------GSTHSTVSPASTTTPGLSEESTT--VYSSSRGSTE 799
Query: 1502 GSYHEQSVDRSGHSGYHHSHTTPQGRSDASHGQSGPRSASRQTRNEEQSGDGSRHSGSRH 1561
+ S S H TT R ++H ++ EE + + ++
Sbjct: 800 TTVFPHSTTTSVHG---EEPTTFHSRPASTHTTLFTEDSTTSGLTEESTAFPGSPASTQT 856
Query: 1562 HEPSTRAGSSRHSQVGQGESAGSKTSRRQGSSVSQDRDSEGHSEDSERRSESA-SRNHYG 1620
P+T + +G+ + +S G+ +S R S S ES SR
Sbjct: 857 GLPATLT----TADLGEESTTFPSSSGSTGTKLSPAR-----STTSGLVGESTPSRLSPS 907
Query: 1621 SAREQSRHGSRNPRSHQEDRASHGHSAESSRQSGTRHAETSSGGQAASSQEQARSSPGER 1680
S + GS S E + S S + + TSSG SS + S PG
Sbjct: 908 STETTTLPGSPTTPSLSEKSTTFYTSPRSPDATLSPATTTSSGVSEESS--TSHSQPGST 965
Query: 1681 HGSRHQQSADSSTDSGTGRRQDSSVVGDSGNRGSSGSQASDSEGHSEESDTQSVSAHGQA 1740
H + DS+T S + +S ++GS+ + S + QS + H
Sbjct: 966 HTTAF---PDSTTTSDLSQEPTTS----HSSQGSTEATLSPGSTTASSLGQQSTTFHSSP 1018
Query: 1741 GPHQQSHQESTRGQSGERSGRSGSFLYQVSTHEQSESAHGRTGPSTGGRQRSRHEQARDS 1800
G ++ + + SG TH + S H P++ + E
Sbjct: 1019 G-------DTETTLLPDDTITSGLVEASTPTHSSTGSLHTTLTPASSTSAGLQEESTTFQ 1071
Query: 1801 SRHSASQEGQDTIRGHPGSSRGGRQGSHYEQSVDSSGHSGSHHSHTTSQERSDVSRGQSG 1860
S S+S DT PG++ V ++ HS + TT S + G
Sbjct: 1072 SWPSSS----DTTPSPPGTTAA-------PVEVSTTYHSRPSSTPTTHFSASSTTLG--- 1117
Query: 1861 SRSVSRQTRNEKQSGDGSRHSGSRHHEASSRADSSRHSQVGQGQSSGPRTSRNQGSSVSQ 1920
RS T + G+ +R S+ VG+ +S + + +++
Sbjct: 1118 -RSEESTTVHSSPGATGTALFPTR---------SATSVLVGEPTTSPISSGSTETTALPG 1167
Query: 1921 DSDSQGHSEDSERWSGS----------ASRNHLGSAWEQSRDGSRHPGSHHEDRAGHGHS 1970
+ + G SE S + S AS G + E + SR +H G
Sbjct: 1168 STTTAGLSEKSTTFYSSPRSPDTTLSPASTTSSGVSEESTTSHSRPGSTHTTAFPGSTTM 1227
Query: 1971 ADSSRQSGTRHTESSSRGQAASSHEQARSSAGERHGSHHQLQSADSSRHSGIGHGQASSA 2030
S++S H+ S S SS G + H S S+ + + +S
Sbjct: 1228 PGVSQESTASHSSPGSTDTTLSPGSTTASSLGPESTTFH--SSPGSTETTLLPDNTTASG 1285
Query: 2031 VRDSGHRGYSGSQASDSEGHSEDSDTQSVSAQGKAGPHQQ--SHKESARGQSGESSGRSG 2088
+ ++ +S S H+ S S + QG++ Q S K++ +S
Sbjct: 1286 LLEASTPVHS----STGSPHTTLSPAGSTTRQGESTTFQSWPSSKDTMPAPPTTTSAFVE 1341
Query: 2089 SFLYQVSTHEQSESTHGQSAPSTGGRQGSHYDQAQDSSRHSASQEGQDTIRGHPGPSRGG 2148
+ + +TH ++ +T GR + ++ HS+ T P P+R
Sbjct: 1342 LSTTSHGSPSSTPTTHFSASSTTLGR------SEESTTVHSSPVATATT----PSPARST 1391
Query: 2149 RQGSHQEQSVDRSGHSGSHHSH----TTSQGRSDASRGQSGS 2186
G +E + S + H +T+ GRS+ SR S
Sbjct: 1392 TSGLVEESTAYHSSPGSTQTMHFPESSTASGRSEESRTSHSS 1433
Score = 90.9 bits (224), Expect = 2e-17
Identities = 340/1567 (21%), Positives = 522/1567 (33%), Gaps = 181/1567 (11%)
Query: 2367 QASDSEGHSEDSDTQSVSAHGQAGPHQQSHQESTRGRSAGRSGRSGSFLYQVSTHEQSES 2426
++S + GHSE+S T HG H +S ST A S S + + S +
Sbjct: 5 ESSTTSGHSEESAT----FHGST-THTKSSTPSTTAALAHTSYHSSLGSTETTHFRDSST 59
Query: 2427 AHGRTGTSTGGRQGSHHKQARDSSRHSTSQEGQDTIHGHPGSSSGGRQGSHYEQLVDRSG 2486
GR+ S ST P SSG + + + G
Sbjct: 60 ISGRSEESKASHSSPDAMATTVLPAGSTPSVLVGDSTPSP-ISSGSMETTALPGSTTKPG 118
Query: 2487 HSGSHHSHTTSQGRSDASH-GHSGSRSASRQTRNDEQSGDGSRHS----GSRHHEASSRA 2541
S + +S D +H S + S + S GS H+ GS S+
Sbjct: 119 LSEKSTTFYSSPRSPDTTHLPASMTSSGVSEESTTSHSRPGSTHTTAFPGSTTMPGLSQE 178
Query: 2542 DSSGHSQVGQGQ---SEGPRTSRNWGSSFSQDSDSQGHSE-----DSERWSG--SASRNH 2591
++ HS G S G T+ + G ++ G +E D+ SG AS
Sbjct: 179 STASHSSPGPTDTTLSPGSTTASSLGPEYTTFHSRPGSTETTLLPDNTTASGLLEASMPV 238
Query: 2592 HGSAQEQLRDGSRHPRSHQEDRAGHGHSADSSRQSGTRHTQTSSGGQAASSHEQARSSAG 2651
H S + S + ++ + HS SS+ + T+S S+
Sbjct: 239 HSSTRSPHTTLSPAGSTTRQGESTTFHSWPSSKDTRPAPPTTTSAFVEPSTT-------- 290
Query: 2652 ERHGSHHQQSADSSRHSGIGHGQASSAVRDSGHRGYSGSQASDNEGHSEDSDTQSVSAHG 2711
SH S+ + H S V +S Y S S H +SDT S G
Sbjct: 291 ----SHGSPSSIPTTHIS-ARSTTSGLVEES--TTYHSSPGSTQTMHFPESDTTS----G 339
Query: 2712 QAGSHQQSHQESARGRSGETSGHSGSFLYQVSTHEQSESSHGWTGPSTRGRQGSRHEQAQ 2771
+ SH + S S S S H SS G T + + +++
Sbjct: 340 RGEESTTSHSSTTHTISSAPSTTSALVEEPTSYH----SSPGSTATTHFPDSSTTSGRSE 395
Query: 2772 DSSRHSASQDGQDTIRGHPGSSRGGRQGYHHEHSVDS-SGHSGSHHSHTTSQGRSDASRG 2830
+S+ +SQD TI S+ G + S S + + TT+ G S+ S
Sbjct: 396 ESTASHSSQDATGTIVLPARSTTSVLLGESTTSPISSGSMETTALPGSTTTPGLSERSTT 455
Query: 2831 QSGSRSASRTT---RNEEQSGDGSRHSGSRHHEASTHADISRHSQAVQGQSEGSRRSRRQ 2887
S + TT + SG + SR STH S G S S S
Sbjct: 456 FHSSPRSPATTLSPASTTSSGVSEESTTSRSRPGSTHTTAFPDSTTTPGLSRHSTTSHSS 515
Query: 2888 GSSVSQDSDSEGHSEDSERWSGSASRNHHGSAQEQLRDGSRHPRSHQEDRAGHGHSADSS 2947
S + + S + GS L GS S ++ + S+
Sbjct: 516 PGSTDTTLLPASTTTSGPSQESTTSHSSSGSTDTALSPGSTTALSFGQESTTFHSNPGST 575
Query: 2948 RQSGTRHTQTSSGGQAASSHEQARSSAGERHGSHHQQSADSSRHSGIGHGQASSAVRDSG 3007
+ + TSSG AS+ + SS G + S SS G+ G++++
Sbjct: 576 HTTLFPDSTTSSGIVEAST--RVHSSTGSPRTT---LSPASSTSPGL-QGESTAFQTHPA 629
Query: 3008 HRGYSGSQASDNEGHSEDSDTQSVSAHGQAGSHQQSHQESARGRSGETSGHSGSFLYQVS 3067
+ S S E+S T H GS +H + S TSGHS S
Sbjct: 630 STHTTPSPPSTATAPVEESTTY----HRSPGSTPTTHFPA----SSTTSGHSEKSTIFHS 681
Query: 3068 THEQSESSHGWTGPSTRGRQGSRHEQAQDSSRHSASQYGQDTIRGHPGSSRGGRQGYHH- 3126
+ + S ++ +T GR S + S + G T PG S Y
Sbjct: 682 SPDASGTTPSSAHSTTSGRGESTTSRISPGSTEITTLPGSTTT---PGLSEASTTFYSSP 738
Query: 3127 ------------------EHSVDSSGHSGSHHS-----HTTSQGRSDASRG-QSGSRSAS 3162
E S S GS HS TT+ G S+ S S SR ++
Sbjct: 739 RSPTTTLSPASMTSLGVGEESTTSRSQPGSTHSTVSPASTTTPGLSEESTTVYSSSRGST 798
Query: 3163 RTT---RNEEQSGDSSRHSVSRHHEASTHADISRHSQAVQGQSE------GSRRSRRQG- 3212
TT + S + ASTH + G +E GS S + G
Sbjct: 799 ETTVFPHSTTTSVHGEEPTTFHSRPASTHTTLFTEDSTTSGLTEESTAFPGSPASTQTGL 858
Query: 3213 ------SSVSQDSDSEGHSEDSERWSGSASRNHRGSVQEQSRHGSRHPRSHH-------- 3258
+ + ++S + S S S +R+ + +S P S
Sbjct: 859 PATLTTADLGEESTTFPSSSGSTGTKLSPARSTTSGLVGESTPSRLSPSSTETTTLPGSP 918
Query: 3259 -----EDRAGHGHSADRSRQSGTRHAETSSGGQAASSHEQARSSPGERHGSRHQQSADSS 3313
+++ +++ RS + A T+S G + S + S PG H + S +S
Sbjct: 919 TTPSLSEKSTTFYTSPRSPDATLSPATTTSSGVSEES-STSHSQPGSTHTTAFPDSTTTS 977
Query: 3314 RHSGIPRGQASSAVRDSRHWGSSGSQASDSEG------HSEESDTQSV--------SGHG 3359
S P SS + S GS + S G HS DT++ SG
Sbjct: 978 DLSQEPTTSHSSQ-GSTEATLSPGSTTASSLGQQSTTFHSSPGDTETTLLPDDTITSGLV 1036
Query: 3360 QAGPHQQSHQES-------ARDRSGGRSGRSGSFLYQVSTHEQSESAHGRTRTSTGRRQG 3412
+A S S A S G S +F S+ + + S G T
Sbjct: 1037 EASTPTHSSTGSLHTTLTPASSTSAGLQEESTTFQSWPSSSDTTPSPPGTTAAPVEVSTT 1096
Query: 3413 SHHEQARDSSRH-SASQ------EGQDTIRGHPGSSRRGRQGSHYEQSV----DRSGHSG 3461
H + + H SAS E T+ PG++ + SV +
Sbjct: 1097 YHSRPSSTPTTHFSASSTTLGRSEESTTVHSSPGATGTALFPTRSATSVLVGEPTTSPIS 1156
Query: 3462 SHHSHTTSQGRSDASRGQSGSRSASRQTRNDEQSGDGSRHSWSHHHEASTQADSSRHSQS 3521
S + TT+ S + G S S + +S D + S ++ ++ HS+
Sbjct: 1157 SGSTETTALPGSTTTAGLS---EKSTTFYSSPRSPDTTLSPASTTSSGVSEESTTSHSRP 1213
Query: 3522 GQGQS-AGPRTSRNQG-SSVSQDSDSQGHSEDSERWSGSASRNHRG--SAQEQSRDGSRH 3577
G + A P ++ G S S S S S D+ GS + + G S S GS
Sbjct: 1214 GSTHTTAFPGSTTMPGVSQESTASHSSPGSTDTTLSPGSTTASSLGPESTTFHSSPGSTE 1273
Query: 3578 PTSHHEDRAGHGHSAESS---RQSGTHHAENSSGG----QAASSHEQARSSAGERHGSHH 3630
T ++ G S+ +G+ H S G Q S+ Q+ S+ + +
Sbjct: 1274 TTLLPDNTTASGLLEASTPVHSSTGSPHTTLSPAGSTTRQGESTTFQSWPSSKDTMPAPP 1333
Query: 3631 QQSADSSRHSGIGHGQASSAVRDSGHRGSSGSQASDSEGHSEDSDTQSVSAHGQAGPHQQ 3690
++ S HG SS + S +S + G SE+S T S A
Sbjct: 1334 TTTSAFVELSTTSHGSPSSTPT------THFSASSTTLGRSEESTTVHSSPVATATTPSP 1387
Query: 3691 SHQESTRGRSAGRSGRSGSFLYQVSTHEQSESAHGRAGPSTGGRQGSRHEQARDSSRHSA 3750
+ ++ + S Q +S +A GR+ S + H + S SA
Sbjct: 1388 ARSTTSGLVEESTAYHSSPGSTQTMHFPESSTASGRSEESRTSHSSTTHTISSPPSTTSA 1447
Query: 3751 SQEGQDTIRGHPGSRRGGRQGSYHEQSVDRSGHS----GSHHSHTTSQGRSDASHGQSGS 3806
E + PGS ++ +S SG S SH S T+ +H +
Sbjct: 1448 LVEEPTSYHSSPGS----IATTHFPESSTTSGRSEESTASHSSPDTNGITPLPAHFTTSG 1503
Query: 3807 RSASRET 3813
R A T
Sbjct: 1504 RIAESTT 1510
Score = 89.4 bits (220), Expect = 7e-17
Identities = 360/1635 (22%), Positives = 558/1635 (34%), Gaps = 232/1635 (14%)
Query: 1638 EDRASHGHSAESSRQSG-TRHAETSSGGQ-AASSQEQARSSPGERHGSRHQQSADSSTDS 1695
E + GHS ES+ G T H ++S+ AA + SS G + + S+ S S
Sbjct: 5 ESSTTSGHSEESATFHGSTTHTKSSTPSTTAALAHTSYHSSLGSTETTHFRDSSTISGRS 64
Query: 1696 GTGRRQDSSVVGDSGNRGSSGSQASDSEGHSEESDTQSVSAHGQAGPHQQSH----QEST 1751
+ SS + +GS S G S S S S A P + ++ST
Sbjct: 65 EESKASHSSPDAMATTVLPAGSTPSVLVGDSTPSPISSGSMETTALPGSTTKPGLSEKST 124
Query: 1752 RGQSGERSGRSGSFLYQVSTH---EQSESAHGRTGPS--TGGRQRSRHEQARDSSRHSAS 1806
S RS + +++ E+S ++H R G + T + S S S
Sbjct: 125 TFYSSPRSPDTTHLPASMTSSGVSEESTTSHSRPGSTHTTAFPGSTTMPGLSQESTASHS 184
Query: 1807 QEGQDTIRGHPGSSRGGRQGSHYEQSVDSSGHSGSHHSHTTSQERSDVSRGQ-SGSRSVS 1865
G PGS+ G Y ++ HS + TT + + G S V
Sbjct: 185 SPGPTDTTLSPGSTTASSLGPEY-----TTFHSRPGSTETTLLPDNTTASGLLEASMPVH 239
Query: 1866 RQTRNEKQSGDGSRHSGSRHHEASSRADSSRHSQVGQGQSSGPRTSRNQGSSVSQDSDSQ 1925
TR+ + +GS + S S S + + P + V + S
Sbjct: 240 SSTRSPHTT---LSPAGSTTRQGESTTFHSWPSS----KDTRPAPPTTTSAFVEPSTTSH 292
Query: 1926 GHSEDSERWSGSASRNHLGSAWEQSRDGSRHPGSHHEDRAGHGHSADSSRQSGTRHTES- 1984
G S S + ++R+ E+S PGS + H +D++ G T S
Sbjct: 293 G-SPSSIPTTHISARSTTSGLVEESTTYHSSPGS---TQTMHFPESDTTSGRGEESTTSH 348
Query: 1985 SSRGQAASSHEQARSSAGERHGSHHQLQSADSSRHSGIGHGQASSAVRDSGHRGYSGSQA 2044
SS SS S+ E S+H + ++ H +
Sbjct: 349 SSTTHTISSAPSTTSALVEEPTSYHSSPGSTATTHF---------------------PDS 387
Query: 2045 SDSEGHSEDSDTQSVSAQGKAGP---HQQSHKESARGQSGESSGRSGSFLYQVSTHEQSE 2101
S + G SE+S T S S+Q G +S G+S S SGS + + S
Sbjct: 388 STTSGRSEES-TASHSSQDATGTIVLPARSTTSVLLGESTTSPISSGSM--ETTALPGST 444
Query: 2102 STHGQSAPSTGGRQGSHYDQAQDSSRHSASQEGQDTIRGHPGPSRGGRQGSHQEQSVDRS 2161
+T G S ST + HS+ + T+ S G + S +S S
Sbjct: 445 TTPGLSERST--------------TFHSSPRSPATTLSPASTTSSGVSEESTTSRSRPGS 490
Query: 2162 GHSGSHHSHTTSQG---RSDASRGQSGSRSASRKTYDKEQSGDGSRHSGSHHHEASSWAD 2218
H+ + TT+ G S S GS + SG + SH S+
Sbjct: 491 THTTAFPDSTTTPGLSRHSTTSHSSPGSTDTTLLPASTTTSGPSQESTTSHSSSGSTDTA 550
Query: 2219 SSRHSLVGQ--GQSSGPRTSRP------------RGSSVSQDSDSEGHSEDSERRSGSAS 2264
S S GQ S S P S + + S S S R + S +
Sbjct: 551 LSPGSTTALSFGQESTTFHSNPGSTHTTLFPDSTTSSGIVEASTRVHSSTGSPRTTLSPA 610
Query: 2265 RNHHGSAQEQSRDGSRHPRSHHEDRAGHGHSAESSRQSGTHHAENSSGGQAASSHEQARS 2324
+ Q +S HP S H + + +S T+H S G ++H A S
Sbjct: 611 SSTSPGLQGESTAFQTHPASTHTTPSPPSTATAPVEESTTYH---RSPGSTPTTHFPASS 667
Query: 2325 SAGERHGSHHQQSADSSRHSGIGHG--QASSAVRDSGHRGSSGSQASDSEGHSEDSDTQS 2382
+ ++ S S I H AS S H +SG S + S S T+
Sbjct: 668 T-----------TSGHSEKSTIFHSSPDASGTTPSSAHSTTSGRGESTTSRISPGS-TEI 715
Query: 2383 VSAHGQAGPHQQSHQESTRGRSAGRSGRSGSFLYQVSTHEQSESAHGRTGTSTGGRQGSH 2442
+ G +T G S S + S + + + TS G + S
Sbjct: 716 TTLPGST---------TTPGLS------EASTTFYSSPRSPTTTLSPASMTSLGVGEEST 760
Query: 2443 HKQARDSSRHSTSQEGQDTIHGHPGSSS---GGRQGSHYEQLVDRSGHSGSHHSHTTSQG 2499
+++ S HST T G S+ +GS + S + H T+
Sbjct: 761 TSRSQPGSTHSTVSPASTTTPGLSEESTTVYSSSRGSTETTVFPHSTTTSVHGEEPTT-- 818
Query: 2500 RSDASHGHSGSRSASRQTRNDEQSG---DGSRHSGSRHHEASSRADSSGHSQVGQGQSEG 2556
H S + T + SG + + GS + + + +G+ +
Sbjct: 819 ----FHSRPASTHTTLFTEDSTTSGLTEESTAFPGSPASTQTGLPATLTTADLGEESTTF 874
Query: 2557 PRTSRNWGSSFS-QDSDSQGHSEDSERWSGSASRNHHGSAQEQLRDGSRHPRSHQEDRAG 2615
P +S + G+ S S + G +S + SR S + GS S E
Sbjct: 875 PSSSGSTGTKLSPARSTTSGLVGES-----TPSRLSPSSTETTTLPGSPTTPSLSEKSTT 929
Query: 2616 HGHSADSSRQSGTRHTQTSSG--GQAASSHEQARSSAGERHGSHHQQSADSSRHSGIGHG 2673
S S + + T TSSG ++++SH Q S +H DS+ S +
Sbjct: 930 FYTSPRSPDATLSPATTTSSGVSEESSTSHSQPGS-------THTTAFPDSTTTSDLSQE 982
Query: 2674 QASSAVRDSGHRGYSGSQASDNEGHSEDSD--TQSVSAHGQAGSHQQSHQESARGRSGET 2731
+S H ++A+ + G + S QS + H G + + SG
Sbjct: 983 PTTS------HSSQGSTEATLSPGSTTASSLGQQSTTFHSSPGDTETTLLPDDTITSGLV 1036
Query: 2732 SGHSGSFLYQVSTHEQSESSHGWTGPSTRGRQGSRHEQAQDSSRHSASQDGQDTIRGHPG 2791
TH + S H P++ G + E S S+S DT PG
Sbjct: 1037 EA-------STPTHSSTGSLHTTLTPASSTSAGLQEESTTFQSWPSSS----DTTPSPPG 1085
Query: 2792 SSRGGRQGYHHEHSVDSSGHSGSHHSHTTSQGRSDASRGQSGSRSASRTTRNEEQSGDG- 2850
++ + HS SS + + +T+ GRS+ S S A+ T +S
Sbjct: 1086 TTAAPVEVSTTYHSRPSSTPTTHFSASSTTLGRSEESTTVHSSPGATGTALFPTRSATSV 1145
Query: 2851 --SRHSGSRHHEASTHADISRHSQAVQGQSEGS----RRSRRQGSSVSQDS-DSEGHSED 2903
+ S ST S G SE S R +++S S S G SE+
Sbjct: 1146 LVGEPTTSPISSGSTETTALPGSTTTAGLSEKSTTFYSSPRSPDTTLSPASTTSSGVSEE 1205
Query: 2904 SERWSGSASRNHHGSAQEQLRDGS-RHPRSHQEDRAGHGH--SADSSRQSGTRHTQTSSG 2960
S + S + GS GS P QE A H S D++ G+ T +S G
Sbjct: 1206 S-----TTSHSRPGSTHTTAFPGSTTMPGVSQESTASHSSPGSTDTTLSPGST-TASSLG 1259
Query: 2961 GQAASSHEQARS-----------SAGERHGSHHQQSADSSRHSGIGHGQASSAVRDSGHR 3009
++ + H S ++G S S+ S H+ + A S R
Sbjct: 1260 PESTTFHSSPGSTETTLLPDNTTASGLLEASTPVHSSTGSPHTTL--SPAGSTTRQGEST 1317
Query: 3010 GYSGSQASDNEGHSEDSDTQ-----SVSAHGQAGSHQQSHQESARGRSGETSGHSGSFLY 3064
+ +S + + + T S ++HG S +H + S T G S
Sbjct: 1318 TFQSWPSSKDTMPAPPTTTSAFVELSTTSHGSPSSTPTTHFSA----SSTTLGRS----- 1368
Query: 3065 QVSTHEQSESSHGWTGPSTRGRQGSRHEQAQDSSRHSASQYGQDTIRGHPGSSRGGRQGY 3124
+ ST S T PS +R + S +++ H SS G Q
Sbjct: 1369 EESTTVHSSPVATATTPS--------------PARSTTSGLVEESTAYH--SSPGSTQTM 1412
Query: 3125 HHEHSVDSSGHSGSHHSHTTSQGRSDASRGQSGSRSASRTTRNEEQSGDSSRHSVSRHH- 3183
H S +SG S S T+ S + S S + E S SS S++ H
Sbjct: 1413 HFPESSTASGR--SEESRTS---HSSTTHTISSPPSTTSALVEEPTSYHSSPGSIATTHF 1467
Query: 3184 -EASTHADISRHSQA 3197
E+ST + S S A
Sbjct: 1468 PESSTTSGRSEESTA 1482
Score = 77.8 bits (190), Expect = 2e-13
Identities = 278/1320 (21%), Positives = 412/1320 (31%), Gaps = 213/1320 (16%)
Query: 238 TIQDEAYDTTDSLLEENKIYERSRSSDGKSSSQVNRSRHENTSQVPLQESRTRKRRGSRV 297
T A TT L+EE+ Y S S T + ES T RG
Sbjct: 300 TTHISARSTTSGLVEESTTYHSSPGS---------------TQTMHFPESDTTSGRGEES 344
Query: 298 SQDRDSEGHSEDSERHSGSA----SRNHHGS----AWEQSRDGSRHPRSHDEDRASH--- 346
+ S H+ S + SA ++H S A D S +E ASH
Sbjct: 345 TTSHSSTTHTISSAPSTTSALVEEPTSYHSSPGSTATTHFPDSSTTSGRSEESTASHSSQ 404
Query: 347 ------------------GHSADSSRQSGTRHAETSSRGQTASSHEQARSSPGERHGSGH 388
G S S SG+ T+ G T + RS+ H S
Sbjct: 405 DATGTIVLPARSTTSVLLGESTTSPISSGSMET-TALPGSTTTPGLSERSTTF--HSSPR 461
Query: 389 QQSADSSRHSATGRGQASSAVSDRGHRGSSGSQASDSEGHSENSDTQSVSGHGKAGLRQQ 448
+ S S T G + + + R GS+ + A + S + H
Sbjct: 462 SPATTLSPASTTSSGVSEESTTSRSRPGSTHTTAFPDSTTTPGLSRHSTTSHSS------ 515
Query: 449 SHQESTRGRSGERSGRSGSSLYQVSTHEQPDSAHGRTGTSTGGRQGSHHEQARDSSRHSA 508
G + ++L ST S T S+ G + A +A
Sbjct: 516 -------------PGSTDTTLLPASTTTSGPSQESTTSHSSSGST----DTALSPGSTTA 558
Query: 509 SQEGQD--TIRGHPGSSRGGRQGSHHEQSVNRSGHSGSHHSHTTSQGRSDAS---HGQSG 563
GQ+ T +PGS+ H+ TTS G +AS H +G
Sbjct: 559 LSFGQESTTFHSNPGST-----------------HTTLFPDSTTSSGIVEASTRVHSSTG 601
Query: 564 SRSASRQTRNEEQSGDGTRHSGSRHHEASSQADSSRHSQVGQGQSSGPRTSRNQGSSVS- 622
S + + G + + H AS+ S S R+ GS+ +
Sbjct: 602 SPRTTLSPASSTSPGLQGESTAFQTHPASTHTTPSPPSTATAPVEESTTYHRSPGSTPTT 661
Query: 623 ---QDSDSQGHSEDSERWSGSASRNHHGSAQEQSRDGSRHPRSHHEDRAGHGHSADSSRK 679
S + GHSE S + S + P S H +G G S S
Sbjct: 662 HFPASSTTSGHSEKSTIFHSSPDAS------------GTTPSSAHSTTSGRGESTTSRIS 709
Query: 680 SGTRHTQNSSSGQAASSHEQARSSAGERHGSRHQLQSADSSRHSGTGHGQASSAVRDSGH 739
G+ +A ++ S S S G G +S +
Sbjct: 710 PGSTEITTLPGSTTTPGLSEASTTFYSSPRSPTTTLSPASMTSLGVGEESTTSRSQPGST 769
Query: 740 RGSSGSQATDSEGHSEDSDTQSVSGHGQAGHHQQSHQESARDRSGERSRRSGSFLYQVST 799
+ +T + G SE+S T S GS V
Sbjct: 770 HSTVSPASTTTPGLSEESTTVYSSSR-------------------------GSTETTVFP 804
Query: 800 HKQSESSHGWTGPSTGVRQGSHHEQA-RDNSRHSASQDGQDTIRGHPGSSRRGRQGSHHE 858
H + S HG + R S H ++S S + G P S++ G +
Sbjct: 805 HSTTTSVHGEEPTTFHSRPASTHTTLFTEDSTTSGLTEESTAFPGSPASTQTGLPATLTT 864
Query: 859 QSVDRSGHSGSHHSHTTSQGRSDASRGQSGSRSASRTTRNEEQSRDGSRHSGSRHHEA-- 916
+ + S +T S A SG S +R S + + GS +
Sbjct: 865 ADLGEESTTFPSSSGSTGTKLSPARSTTSGLVGESTPSRLSPSSTETTTLPGSPTTPSLS 924
Query: 917 -----------SSHADISRHSQAGQGQSEGSRTSRRQGSSVSQDSDSEGHSEDSERWSGS 965
S A +S + G SE S TS Q S + + + +
Sbjct: 925 EKSTTFYTSPRSPDATLSPATTTSSGVSEESSTSHSQPGSTHTTAFPDSTTTSDLSQEPT 984
Query: 966 ASRNHRGSAQEQSRHGSRHPRSHHEDRAGHGHSADSSRQSGTPHAETSSGGQAASSHEQA 1025
S + +GS + GS S + S + + P +SG AS+
Sbjct: 985 TSHSSQGSTEATLSPGSTTASSLGQQSTTFHSSPGDTETTLLPDDTITSGLVEAST--PT 1042
Query: 1026 RSSPGERHGSRHQQSADSSRHSGIPRRQASSAVRDSGHWGSSGSQASDSEGHSEESDTQS 1085
SS G H + + SS +G+ Q S S W SS G + S
Sbjct: 1043 HSSTGSLHTT---LTPASSTSAGL---QEESTTFQS--WPSSSDTTPSPPGTTAAPVEVS 1094
Query: 1086 VSGHGQDGPHQQSHQESARDWSGGRSGRSGSFIYQVSTHEQSESAHGR----TRTSTGRR 1141
+ H + +H SA + GRS S +T S A G TR++T
Sbjct: 1095 TTYHSRPSSTPTTH-FSASSTTLGRSEES-------TTVHSSPGATGTALFPTRSATSVL 1146
Query: 1142 QGSHHEQARDSSRHSASQEGQDTIRAHPGS--RRGGRQGSHHEQSVDRSGHSGSHHSHTT 1199
G S G A PGS G + S S RS + + TT
Sbjct: 1147 VG--------EPTTSPISSGSTETTALPGSTTTAGLSEKSTTFYSSPRSPDTTLSPASTT 1198
Query: 1200 SQGRSDASHGQSGSRSASRQTRKDKQSGDGSRHSGSRHHEAASWADSSRHSQVGQEQ--- 1256
S G S+ S S SR S T + GS S ++ HS G
Sbjct: 1199 SSGVSEES-TTSHSRPGSTHT---------TAFPGSTTMPGVSQESTASHSSPGSTDTTL 1248
Query: 1257 SSGSRTSRHQGSSVSQDSDSERHSD-----DSERLSG--SASRNHHGSSREQSRDGSRHP 1309
S GS T+ G + S ++ D+ SG AS H S+ S
Sbjct: 1249 SPGSTTASSLGPESTTFHSSPGSTETTLLPDNTTASGLLEASTPVHSSTGSPHTTLSPAG 1308
Query: 1310 GFHQEDRASHGHSADSSRQS--GTHHTESSSHGQAVSSHEQARSSPGERHGSRHQQSADS 1367
++ ++ S SS+ + T S+ + +SH S+P + S
Sbjct: 1309 STTRQGESTTFQSWPSSKDTMPAPPTTTSAFVELSTTSHGSPSSTPTTHFSASSTTLGRS 1368
Query: 1368 SRHSGIGHRQASSAVRDSGHRGSSGSQVTNSEG-HSEDSDTQ------SVSAHGQAGPHQ 1420
+ + ++A S R ++ V S HS TQ S +A G++ +
Sbjct: 1369 EESTTVHSSPVATATTPSPARSTTSGLVEESTAYHSSPGSTQTMHFPESSTASGRSEESR 1428
Query: 1421 QSHKESARGQSGESSGRSRSFLYQVSSHEQSES---THGQTAPSTGGRQGSRHEQARNSS 1477
SH + S S S S H S TH + +T GR S A +SS
Sbjct: 1429 TSHSSTTHTISSPPSTTSALVEEPTSYHSSPGSIATTHFPESSTTSGR--SEESTASHSS 1486
>gi|116008442 zinc finger CCCH-type containing 13 [Homo sapiens]
Length = 1564
Score = 110 bits (276), Expect = 2e-23
Identities = 297/1502 (19%), Positives = 509/1502 (33%), Gaps = 213/1502 (14%)
Query: 273 RSRHENTSQVPLQESRTRKRRGS--RVSQDRDSEGHSEDSERHSGSASRNHHGSAWEQSR 330
R+ E++S V + SR R R +++++R E E+ E WE +R
Sbjct: 103 RNTEESSSPVRKESSRGRHREKEDIKITKERTPESEEENVE--------------WETNR 148
Query: 331 DGSRHPRSHDEDRASHGHSADSSRQSGTRHAETSSRGQTAS----------SHEQARS-- 378
D S + + + H S + RQ R + S E RS
Sbjct: 149 DDSDNGDINYD--YVHELSLEMKRQKIQRELMKLEQENMEKREEIIIKKEVSPEVVRSKL 206
Query: 379 --SPGERHGSGHQQSADSSRHS-ATGRGQASSAVSDRGHRGSSGSQASDSEGHSENSDTQ 435
SP R S + S + S A+ + + +SAVS S D + +S+ + ++
Sbjct: 207 SPSPSLRKSSKSPKRKSSPKSSSASKKDRKTSAVS---------SPLLDQQRNSKTNQSK 257
Query: 436 SVSGHGKAGLRQQSHQESTRGRSGERSGRSGSSLYQVSTHEQPDSAHGRTGTSTGGRQGS 495
K G R S G+ Y+V + + G+ GR
Sbjct: 258 ------KKGPRTPSPPPPIP--EDIALGKKYKEKYKVKDRIEEKTRDGKDR----GRDFE 305
Query: 496 HHEQARDSSRHSASQEGQD----TIRGHPGSSRGGRQGSHHEQSVNRSGHSGSHHSHT-T 550
+ RD R S S GQ + R H SS+ G H S R + T T
Sbjct: 306 RQREKRDKPR-STSPAGQHHSPISSRHHSSSSQSGSSIQRHSPSPRRKRTPSPSYQRTLT 364
Query: 551 SQGRSDASHGQSGSRSASRQTRNEEQSGDGTRHSGSRHHEASSQADSSRHS--QVGQGQS 608
R AS S S S+ ++ ++ + R G HE +SQ+ RH + +G+
Sbjct: 365 PPLRRSASPYPSHSLSSPQRKQSPPRHRSPMREKGRHDHERTSQSHDRRHERREDTRGKR 424
Query: 609 SGPRTSRNQGSSVSQDSDSQGHSEDSERWSGSASRNHHGS-----------------AQE 651
+ SR + S S+ H +D E G R+ + ++
Sbjct: 425 DREKDSREEREYEQDQSSSRDHRDDREPRDGRDRRDARDTRDRRELRDSRDMRDSREMRD 484
Query: 652 QSRD--GSRHPRSHHEDRAGHGH----SADSSRKSGTRHTQNSSSGQAASSHEQARSSAG 705
SRD SR PR R H + D+ RK T ++ S G+ E +R+
Sbjct: 485 YSRDTKESRDPRDSRSTRDAHDYRDREGRDTHRKEDTYPEESRSYGRNHLREESSRTEI- 543
Query: 706 ERHGSRHQLQSADSSRHSGTGHGQASSAVRDSGHRGSSGSQATDSEGHSEDSDT-QSVSG 764
R+ SR++ +S + G G+ + + G RGS GSQ +S D+ ++ S
Sbjct: 544 -RNESRNESRSEIRNDRMGRSRGRVPE-LPEKGSRGSRGSQIDSHSSNSNYHDSWETRSS 601
Query: 765 HGQAGHH-QQSHQESARD-----RSGERSRRSGSFLYQVSTHKQSESSHGWTGPSTGVR- 817
+ + + ++ +++ ARD R GER RR Q PS+ +R
Sbjct: 602 YPERDRYPERDNRDQARDSSFERRHGERDRRDNRERDQ--------------RPSSPIRH 647
Query: 818 QGSHHEQARDNSRHSASQDGQDTIRGHPGSSRRGRQGSHHEQSVDRSGHSGSHHSHTTSQ 877
QG + E RD R D D R R + E+ +R
Sbjct: 648 QGRNDELERDERREERRVDRVDDRRDERARERDRERERDRERERERERERDREREKEREL 707
Query: 878 GRSDASRGQSGSRSASRTTRNEEQSRDGSRHSGSRHHEASSHADISRHSQAGQGQSEGSR 937
R + +R + R R R ++ RD H R E + R + + + E R
Sbjct: 708 ER-ERAREREREREKER-DRERDRDRD---HDRERERERERDREKEREREREERERERER 762
Query: 938 TSRRQGSSVSQDSDSEGHSEDSER---WSG-SASRNHRGSAQEQSRHGSRHPRSHHEDRA 993
R+ + + ++ ER W R+ R +E+ R R+PR H++R
Sbjct: 763 ERERERERERERERARERDKERERQRDWEDKDKGRDDRREKREEIRE-DRNPRDGHDER- 820
Query: 994 GHGHSADSSRQSGTPHAETSSGGQAASSHEQARSSPGERHGSRHQQSADSSRHSGIPRRQ 1053
S R G+P S + S + + G+ +H+ + R
Sbjct: 821 ---KSKKRYRNEGSPSPRQSPKRRREHSPDSDAYNSGDDKNEKHRLLSQVVRPQESRSLS 877
Query: 1054 ASSAVRD-SGHWGSSG--SQASDSEGHSEESDTQSVSGHGQDGPHQQSHQESARDWSGGR 1110
S D G W + +S EE + + Q ES+R +
Sbjct: 878 PSHLTEDRQGRWKEEDRKPERKESSRRYEEQELKEKVSSVDKQREQTEILESSRMRAQDI 937
Query: 1111 SGRSGSFIYQVSTHEQSESAHGRTRTSTGRRQGSHHEQARDSSRHSASQEGQDTIRAHPG 1170
G +Q E S+ AH + ++ ++ D + G + G
Sbjct: 938 IGH-----HQSEDRETSDRAHDENKKKAKIQKKPIKKKKEDD---VGIERGNIETTSEDG 989
Query: 1171 SRRGGRQGSHHEQSVDRSGHSGSHHSHTTSQGRSDASHGQSGSRSASRQTRKDK----QS 1226
++G ++S+++ S + + + S + G R+ T+++
Sbjct: 990 QVFSPKKG-QKKKSIEKKRKKSKGDSDISDEEAAQQSKKKRGPRTPPITTKEELVEMCNG 1048
Query: 1227 GDGSRHSGSRHHEAA--SWADSSRHSQVGQEQSSGSRTSRHQGSSVSQDSDSERHSDDSE 1284
+G + + A W+D + ++ + T+ GS+ S
Sbjct: 1049 KNGILEDSQKKEDTAFSDWSDEDVPDRTEVTEAEHTATATTPGSTPSP------------ 1096
Query: 1285 RLSGSASRNHHGSSREQSRDGSRHPGFHQEDRASHGHSADSSRQSGTHHTESSSHGQAVS 1344
LS ++ + + S SA + S T +++
Sbjct: 1097 -LSSLLPPPPPVATATATTVPATLAATTAAAATSFSTSAITISTSATPTNTTNNTFANED 1155
Query: 1345 SHEQARSSPGERHGSRHQQSADSSRHSGIGHRQASSAVRDSGHRGSSGSQVTNSEGHSED 1404
SH + + E+ + H D+ + +++SS + +R + ++ S
Sbjct: 1156 SHRKCHRTRVEKVETPHVTIEDAQHRKPMDQKRSSSLGSNRSNRSHTSGRL-----RSPS 1210
Query: 1405 SDTQSVSAHGQAGPHQQSH---KESARGQSGESSGRSRSFLYQVSSHEQSESTHGQTAPS 1461
+D+ S Q+G + H ++ + +S E +G +S + Q+ E S ST
Sbjct: 1211 NDSAHRSGDDQSGRKRVLHSGSRDREKTKSLEITGERKSRIDQLKRGEPSRST------- 1263
Query: 1462 TGGRQGSRHEQARNSSRHSASQDGQDTIRGHPGSSRGGRQGSYHEQSVDRSGH--SGYHH 1519
+ RQ SR +R SS S DR H SG
Sbjct: 1264 SSDRQDSRSHSSRRSSPES-----------------------------DRQVHSRSGSFD 1294
Query: 1520 SHTTPQGRSDASHGQSGPRSASRQTRNEEQSGDGSRHSGSRHHEPSTRAGSSRHSQVGQG 1579
S Q R H + R R TR E D + R+ + R + +
Sbjct: 1295 SRDRLQERDRYEHDRERERE-RRDTRQREWDRDADK-DWPRNRDRDRLRERERERERDKR 1352
Query: 1580 ESAGSKTSRRQGSSVSQDRDSEGHSEDSERRSESASR-------NHYGSAREQSRHGSRN 1632
+ R SV +DRD + + ES R H SR
Sbjct: 1353 RDLDRERERLISDSVERDRDRDRDRTFESSQIESVKRCEAKLEGEHERDLESTSRDSLAL 1412
Query: 1633 PRSHQEDRASHGHSAESSRQSGTRHAETSSGGQAASSQEQARSSPGERHGSRHQQSADSS 1692
+ + E + +S E+ G S + A S G G ++ +D
Sbjct: 1413 DKERMDKDLGSVQGFEETNKS--ERTESLEAGDDESKLDDAHSL-GSGAGEGYEPISDDE 1469
Query: 1693 TD 1694
D
Sbjct: 1470 LD 1471
Score = 102 bits (255), Expect = 6e-21
Identities = 257/1340 (19%), Positives = 452/1340 (33%), Gaps = 204/1340 (15%)
Query: 102 RKHSHHDKHEDNKQEENKENRKRPSSLERRNNRKGNKGRSKSPR-----ETGGKRHESSS 156
+K+ K +D +E+ ++ + R ER+ ++ +K RS SP + H SSS
Sbjct: 278 KKYKEKYKVKDRIEEKTRDGKDRGRDFERQREKR-DKPRSTSPAGQHHSPISSRHHSSSS 336
Query: 157 EK-KERKGYSPTHREE-----EYGKNHHNSSKKEKNKTENTRLGDNRKRLSERLEEKEDN 210
+ + +SP+ R + Y + ++ + + L +++ S
Sbjct: 337 QSGSSIQRHSPSPRRKRTPSPSYQRTLTPPLRRSASPYPSHSLSSPQRKQSPPRHRSPMR 396
Query: 211 EEGVYDYENTGRMTQKWIQSGHIATYYTIQDEAYDTTDSLLEENKIYERSRSSDGKSSSQ 270
E+G +D+E T + ++ + DT E E +SSS+
Sbjct: 397 EKGRHDHERTSQ------------SHDRRHERREDTRGKRDREKDSREEREYEQDQSSSR 444
Query: 271 VNRSRHENTSQVPLQESR-TRKRRGSRVSQDRDSEGHSEDSERHSGSASRNHHGSAWEQS 329
+R E +++R TR RR R S+D D R + ++S
Sbjct: 445 DHRDDREPRDGRDRRDARDTRDRRELRDSRDMRDSREMRDYSRDT------------KES 492
Query: 330 RDGSRHPRSHDEDRASHGH----SADSSRQSGTRHAETSSRGQTASSHEQARSSPGERHG 385
RD PR R +H + D+ R+ T E+ S G+ +H + SS E
Sbjct: 493 RD----PRDSRSTRDAHDYRDREGRDTHRKEDTYPEESRSYGR---NHLREESSRTEIRN 545
Query: 386 SGHQQSADSSRHSATGRGQASSAVSDRGHRGSSGSQASDSEGHSENS------DTQSV-- 437
+S R+ GR + V + +GS GS+ S + HS NS +T+S
Sbjct: 546 ESRNESRSEIRNDRMGRSR--GRVPELPEKGSRGSRGSQIDSHSSNSNYHDSWETRSSYP 603
Query: 438 --SGHGKAGLRQQSHQESTRGRSGERSGRSGSSLYQVSTHEQPDSAHGRTGTSTGGRQGS 495
+ + R Q+ S R GER R +Q S+ R QG
Sbjct: 604 ERDRYPERDNRDQARDSSFERRHGERDRRDNRE------RDQRPSSPIR-------HQGR 650
Query: 496 HHEQARDSSRHSASQEGQDTIRGHPGSSRGGRQGSHHEQSVNRSGHSGSHHSHTTSQGRS 555
+ E RD R + D R R + E+ R R
Sbjct: 651 NDELERDERREERRVDRVDDRRDERARERDRERERDRERERERERERDREREKERELERE 710
Query: 556 DASHGQSGSRSASRQTRNEEQSGDGTRHSGSRHHEASSQADSSRHSQVGQGQSSGPRTSR 615
A R R+ + + H R E + R + + + R
Sbjct: 711 RAR-----EREREREKERDRERDRDRDHDRERERERERDREKEREREREERERERERERE 765
Query: 616 NQGSSVSQDSDSQGHSEDSER---WSG-SASRNHHGSAQEQSRDGSRHPRSHHEDRAGHG 671
+ + ++ ++ ER W R+ +E+ R+ R+PR H++R
Sbjct: 766 RERERERERERARERDKERERQRDWEDKDKGRDDRREKREEIRE-DRNPRDGHDER---- 820
Query: 672 HSADSSRKSGTRHTQNSSSGQAASSHEQARSSAGERHGSRHQLQSADSSRHSGTGHGQAS 731
S R G+ + S + S + ++G+ +H+L S
Sbjct: 821 KSKKRYRNEGSPSPRQSPKRRREHSPDSDAYNSGDDKNEKHRL---------------LS 865
Query: 732 SAVRDSGHRGSSGSQAT-DSEGHSEDSDTQSVSGHGQAGHHQQSHQESARDRSGERSRRS 790
VR R S S T D +G ++ D + + +Q +E S ++ R
Sbjct: 866 QVVRPQESRSLSPSHLTEDRQGRWKEEDRKPERKESSRRYEEQELKEKV--SSVDKQREQ 923
Query: 791 GSFLYQVSTHKQSESSHGWTGPSTGVRQGSHHEQARDNSRHSASQDGQDT-IRGHPGSSR 849
L Q H H + R+ S + ++ + I+ P +
Sbjct: 924 TEILESSRMRAQDIIGH-------------HQSEDRETSDRAHDENKKKAKIQKKPIKKK 970
Query: 850 RGRQGSHHEQSVDRSGHSGSHHSHTTSQGRSDASRGQSGSRSASRTTRNEEQSRDGSRHS 909
+ +++ + G S Q + + + S+ S + +EE ++ +
Sbjct: 971 KEDDVGIERGNIETTSEDGQVFSPKKGQKKKSIEKKRKKSKGDSDIS-DEEAAQQSKKKR 1029
Query: 910 GSRHHEASSHADISRHSQAGQGQSEGSRTSRRQGSSVSQDSDSEGHSEDSERWSGSASRN 969
G R ++ ++ G E S+ S D D +E +E +A+
Sbjct: 1030 GPRTPPITTKEELVEMCNGKNGILEDSQKKEDTAFSDWSDEDVPDRTEVTEA-EHTATAT 1088
Query: 970 HRGSAQE------------QSRHGSRHPRSHHEDRAGHGHSADSS----RQSGTPHAETS 1013
GS + + P + A S +S S TP T+
Sbjct: 1089 TPGSTPSPLSSLLPPPPPVATATATTVPATLAATTAAAATSFSTSAITISTSATPTNTTN 1148
Query: 1014 SGGQAASSHEQARSSPGERHGSRHQQSADSSRHSGIPRRQASSAVRDSGHWGSSGSQASD 1073
+ SH + + E+ + H D+ + ++++SS GS+ S S
Sbjct: 1149 NTFANEDSHRKCHRTRVEKVETPHVTIEDAQHRKPMDQKRSSSL-------GSNRSNRSH 1201
Query: 1074 SEG--HSEESDTQSVSGHGQDGPHQQSHQESARDWSGGRSGRSGSFIYQVSTHEQSESAH 1131
+ G S +D+ SG Q G + H SG R E+++S
Sbjct: 1202 TSGRLRSPSNDSAHRSGDDQSGRKRVLH-------SGSRD------------REKTKSLE 1242
Query: 1132 GRTRTSTGRRQGSHHEQARDSSRHSASQEGQDTIRAHPGSRRGGRQGSHHEQSVDRSGHS 1191
TG R+ + R S S + QD+ R+H SRR + S S
Sbjct: 1243 -----ITGERKSRIDQLKRGEPSRSTSSDRQDS-RSH-SSRRSSPESDRQVHS-----RS 1290
Query: 1192 GSHHSHTTSQGRSDASHGQSGSRSASRQTRKDKQSGDGSRHSGSRHHEAASWADSSRHSQ 1251
GS S Q R H + R R TR+ + D + R+ + + R +
Sbjct: 1291 GSFDSRDRLQERDRYEHDRERERE-RRDTRQREWDRDADK-DWPRNRDRDRLRERERERE 1348
Query: 1252 VGQEQSSGSRTSRHQGSSVSQDSDSER----HSDDSE-------RLSGSASRNHHGSSRE 1300
+ + R SV +D D +R S E +L G R+ +SR+
Sbjct: 1349 RDKRRDLDRERERLISDSVERDRDRDRDRTFESSQIESVKRCEAKLEGEHERDLESTSRD 1408
Query: 1301 --------QSRDGSRHPGFHQEDRASHGHS---ADSSRQSGTHHTESSSHGQA---VSSH 1346
+D GF + +++ S D + H+ S G+ +S
Sbjct: 1409 SLALDKERMDKDLGSVQGFEETNKSERTESLEAGDDESKLDDAHSLGSGAGEGYEPISDD 1468
Query: 1347 EQARSSPGERHGSRHQQSAD 1366
E G+ QQ +
Sbjct: 1469 ELDEILAGDAEKREDQQDEE 1488
Score = 97.4 bits (241), Expect = 2e-19
Identities = 286/1493 (19%), Positives = 486/1493 (32%), Gaps = 193/1493 (12%)
Query: 2226 GQGQSSGPRTS--------RPRGSSVSQDSDSEGHSEDSERRSG----SASRNHHGSAQE 2273
G+G SS R S R R + QD D+E ++E S +SR H ++
Sbjct: 67 GKGYSSNYRRSPERPTGDLRERMKNKRQDVDTEPQKRNTEESSSPVRKESSRGRHREKED 126
Query: 2274 QSRDGSRHPRSHHEDRAGHGHSAESSRQSGTHHAENSSGGQAASSHEQARSSAGERHGSH 2333
R P S E+ + +S + + + Q E+
Sbjct: 127 IKITKERTPESEEENVEWETNRDDSDNGDINYDYVHELSLEMKRQKIQRELMKLEQENME 186
Query: 2334 HQQSA----DSSRHSGIGHGQASSAVRDSGHRGSSGSQASDSEGHSEDSDTQSVSAHGQA 2389
++ + S S ++R S S S +D T +VS+
Sbjct: 187 KREEIIIKKEVSPEVVRSKLSPSPSLRKSSKSPKRKSSPKSSSASKKDRKTSAVSSPLL- 245
Query: 2390 GPHQQSHQESTRGRSAGRS--------------GRSGSFLYQVSTHEQSESAHGRTGTST 2435
QQ + ++ + + G G+ Y+V + ++ G+
Sbjct: 246 --DQQRNSKTNQSKKKGPRTPSPPPPIPEDIALGKKYKEKYKVKDRIEEKTRDGKDR--- 300
Query: 2436 GGRQGSHHKQARDSSRHSTSQEGQ-----DTIHGHPGSSSGGRQGSHYEQLVDRSGHSGS 2490
GR ++ RD R STS GQ + H S SG H + S S
Sbjct: 301 -GRDFERQREKRDKPR-STSPAGQHHSPISSRHHSSSSQSGSSIQRHSPSPRRKRTPSPS 358
Query: 2491 HHSHTTSQGRSDASHGHSGSRSASRQTRNDEQSGDGSRHSGSRHHEASSRADSSGHS--Q 2548
+ T R AS S S S+ ++ ++ + R G HE +S++ H +
Sbjct: 359 YQRTLTPPLRRSASPYPSHSLSSPQRKQSPPRHRSPMREKGRHDHERTSQSHDRRHERRE 418
Query: 2549 VGQGQSEGPRTSRNWGSSFSQDSDSQGHSEDSERWSGSASRNHHGSA-QEQLRDG----- 2602
+G+ + + SR S S+ H +D E G R+ + + +LRD
Sbjct: 419 DTRGKRDREKDSREEREYEQDQSSSRDHRDDREPRDGRDRRDARDTRDRRELRDSRDMRD 478
Query: 2603 -------------SRHPRSHQEDRAGHGH----SADSSRQSGTRHTQTSSGGQAASSHEQ 2645
SR PR + R H + D+ R+ T ++ S G+ +H +
Sbjct: 479 SREMRDYSRDTKESRDPRDSRSTRDAHDYRDREGRDTHRKEDTYPEESRSYGR---NHLR 535
Query: 2646 ARSSAGERHGSHHQQSADSSRHSGIGHGQASSAVRDSGHRGYSGSQASDNEGHSEDSDTQ 2705
SS E +S R+ +G + V + +G GS+ S + HS +S+
Sbjct: 536 EESSRTEIRNESRNESRSEIRNDRMGRSRGR--VPELPEKGSRGSRGSQIDSHSSNSN-- 591
Query: 2706 SVSAHGQAGSHQQSHQESAR--GRSGETSGHSGSFLYQVSTHEQSESSHGWTGPSTRGR- 2762
+ + + S+ E R R SF + ++ ++ PS+ R
Sbjct: 592 ----YHDSWETRSSYPERDRYPERDNRDQARDSSFERRHGERDRRDNRERDQRPSSPIRH 647
Query: 2763 QGSRHEQAQDSSRHSASQDGQDTIRGHPGSSRGGRQGYHHEHSVDSSGHSGSHHSHTTSQ 2822
QG E +D R D D R R + E + +
Sbjct: 648 QGRNDELERDERREERRVDRVDDRRDERARERDRERERDRERERERERERDRER-----E 702
Query: 2823 GRSDASRGQSGSRSASRTTRNEEQSGDGSRHSGSRHHEASTHADISRHSQAVQGQSEGSR 2882
+ R ++ R R + + H R E + R + + + E R
Sbjct: 703 KERELERERAREREREREKERDRERDRDRDHDRERERERERDREKEREREREERERERER 762
Query: 2883 RSRRQGSSVSQDSDSEGHSEDSER---WSGS-ASRNHHGSAQEQLRDGSRHPRSHQEDRA 2938
R+ + + ++ ER W R+ +E++R+ R+PR ++R
Sbjct: 763 ERERERERERERERARERDKERERQRDWEDKDKGRDDRREKREEIRE-DRNPRDGHDERK 821
Query: 2939 G----HGHSADSSRQSGTRHTQTSSGGQAASSHEQARSSAGERHGSHHQQSADSSRHSGI 2994
+ S RQS R + S A +S +
Sbjct: 822 SKKRYRNEGSPSPRQSPKRRREHSPDSDAYNSGDDKNEK--------------------- 860
Query: 2995 GHGQASSAVRDSGHRGYSGSQAS-DNEGHSEDSDTQSVSAHGQAGSHQQSHQESARGRSG 3053
H S VR R S S + D +G ++ D + +Q +E
Sbjct: 861 -HRLLSQVVRPQESRSLSPSHLTEDRQGRWKEEDRKPERKESSRRYEEQELKEKVS---- 915
Query: 3054 ETSGHSGSFLYQVSTHEQSESSHGWTGPSTRGRQGSRHEQAQD---SSRHSASQYGQDTI 3110
S +Q E + R + H Q++D S R + I
Sbjct: 916 -------------SVDKQREQTEILESSRMRAQDIIGHHQSEDRETSDRAHDENKKKAKI 962
Query: 3111 RGHPGSSRGGRQGYHHEHSVDSSGHSGSHHSHTTSQGRSDASRGQSGSRSASRTTRNEEQ 3170
+ P + +++++ G S Q + + + S+ S + +EE
Sbjct: 963 QKKPIKKKKEDDVGIERGNIETTSEDGQVFSPKKGQKKKSIEKKRKKSKGDSDIS-DEEA 1021
Query: 3171 SGDSSRHSVSRHHEASTHADISRHSQAVQGQSEGSRRSRRQGSSVSQDSDSEGHSEDSER 3230
+ S + R +T ++ G E S++ S D D +E +E
Sbjct: 1022 AQQSKKKRGPRTPPITTKEELVEMCNGKNGILEDSQKKEDTAFSDWSDEDVPDRTEVTEA 1081
Query: 3231 WSGSASRNHRGSVQEQSRHGSRHPRSHHEDRAGHGHSADRSRQSGTRHAETSSGGQAASS 3290
+A+ GS P S +A + T A T++ + S+
Sbjct: 1082 -EHTATATTPGSTPS--------PLSSLLPPPPPVATATATTVPATLAATTAAAATSFST 1132
Query: 3291 HEQARSSPGERHGSRHQQSADSSRHSGIPRGQASSA------VRDSRHWGSSGSQASDSE 3344
S+ + + A+ H R + + D++H + S S
Sbjct: 1133 SAITISTSATPTNTTNNTFANEDSHRKCHRTRVEKVETPHVTIEDAQHRKPMDQKRSSSL 1192
Query: 3345 GHSEESDTQSVSGHGQAGPHQQSHQESARDRSGG-RSGRSGSFLYQVSTHEQSESAHGRT 3403
G S S+ SG ++ + +H+ S D+SG R SGS E+++S
Sbjct: 1193 G-SNRSNRSHTSGRLRSPSNDSAHR-SGDDQSGRKRVLHSGS-----RDREKTKSLE--- 1242
Query: 3404 RTSTGRRQGSHHEQARDSSRHSASQEGQDTIRGHPGSSRRGRQGSHYEQSVDRSGH--SG 3461
TG R+ + R S S + QD+ R H SSRR S DR H SG
Sbjct: 1243 --ITGERKSRIDQLKRGEPSRSTSSDRQDS-RSH--SSRRSSPES------DRQVHSRSG 1291
Query: 3462 SHHSHTTSQGRSDASRGQSGSRSASRQTRNDEQSGDGSRHSWSHHHEASTQADSSRHSQS 3521
S S Q R + R R TR E D + W + + + R +
Sbjct: 1292 SFDSRDRLQERDRYEHDRERERE-RRDTRQREWDRDADK-DWPRNRDRDRLRERERERER 1349
Query: 3522 GQGQSAGPRTSRNQGSSVSQDSD-------SQGHSEDSERWSGSASRNHRGSAQEQSRDG 3574
+ + R SV +D D E +R H + SRD
Sbjct: 1350 DKRRDLDRERERLISDSVERDRDRDRDRTFESSQIESVKRCEAKLEGEHERDLESTSRDS 1409
Query: 3575 SRHPTSHHEDRAGHGHSAESSRQSGTHHAENSSGGQAASSHEQAR---SSAGE 3624
+ G E + +S E+ G S + A S AGE
Sbjct: 1410 LALDKERMDKDLGSVQGFEETNKS--ERTESLEAGDDESKLDDAHSLGSGAGE 1460
Score = 89.4 bits (220), Expect = 7e-17
Identities = 266/1388 (19%), Positives = 458/1388 (32%), Gaps = 188/1388 (13%)
Query: 1379 SSAVRDSGHRGSSGSQVTNSEGHSEDSDTQSVSA----HGQAGPHQQSHKESARGQSGE- 1433
S ++R S S +S +D T +VS+ + QS K+ R S
Sbjct: 209 SPSLRKSSKSPKRKSSPKSSSASKKDRKTSAVSSPLLDQQRNSKTNQSKKKGPRTPSPPP 268
Query: 1434 ------SSGRSRSFLYQVSSHEQSESTHGQTAPSTGGRQGSRHEQARNSSRHSASQDGQD 1487
+ G+ Y+V + ++ G+ GR R + R+ R S S GQ
Sbjct: 269 PIPEDIALGKKYKEKYKVKDRIEEKTRDGKDR----GRDFERQREKRDKPR-STSPAGQH 323
Query: 1488 ----TIRGHPGSSRGGRQGSYHEQSV--DRSGHSGYHHSHTTPQGRSDA---SHGQSGPR 1538
+ R H SS+ G H S R+ Y + T P RS + SH S P+
Sbjct: 324 HSPISSRHHSSSSQSGSSIQRHSPSPRRKRTPSPSYQRTLTPPLRRSASPYPSHSLSSPQ 383
Query: 1539 SASRQTRNEEQSGDGSRHSGSRHHEPSTRAGSSRHSQVGQGESAGSKTSRRQGSSVSQDR 1598
R+ + RH HE ++++ RH RR+ + +DR
Sbjct: 384 RKQSPPRHRSPMREKGRHD----HERTSQSHDRRHE-------------RREDTRGKRDR 426
Query: 1599 DSEGHSEDSERRSESASRNHYGSAREQSRHGSRNPRSHQEDRASHGHSAESSRQSGTRHA 1658
+ + E + +S+SR+H + R+ R ++ R +S +R
Sbjct: 427 EKDSREEREYEQDQSSSRDHRDDREPRDGRDRRDARDTRDRR----ELRDSRDMRDSREM 482
Query: 1659 ETSSGGQAASSQEQARSSPGERHGSRHQQSADSSTDSGTGRRQDSSVVGDSGNRGSSGSQ 1718
S S + S + H R ++ D+ T + S + SS ++
Sbjct: 483 RDYSRDTKESRDPRDSRSTRDAHDYRDREGRDTHRKEDTYPEESRSYGRNHLREESSRTE 542
Query: 1719 ASDSEGHSEESDTQSVSAHGQAGPHQQSHQESTRGQSGERSGRSGSFLYQVSTHEQSESA 1778
+ + S+ ++ G + ++ +RG G Q+ +H + +
Sbjct: 543 IRNESRNESRSEIRNDRMGRSRGRVPELPEKGSRGSRGS----------QIDSHSSNSNY 592
Query: 1779 HGRTGPSTGGRQRSRH------EQARDSS---RHSASQEGQDTIRGHPGSSRGGRQGSHY 1829
H + +R R+ +QARDSS RH + R SS QG +
Sbjct: 593 HDSWETRSSYPERDRYPERDNRDQARDSSFERRHGERDRRDNRERDQRPSSPIRHQGRND 652
Query: 1830 EQSVDSSGHSGSHHSHTTSQERSDVSRGQSGSRSVSRQTRNEKQSGDGSRHSGSRHHEAS 1889
E D ++ R + R R+ E++ E +
Sbjct: 653 ELERDERREERRVDRVDDRRDERARERDRERERDRERERERERERDREREKERELERERA 712
Query: 1890 SRADSSRHSQVGQGQSSGPRTSRNQGSSVSQDSDSQGHSEDSERWSGSASRNHLGSAWEQ 1949
+ R + + + R + +D + + E ER E+
Sbjct: 713 REREREREKERDRERDRDRDHDRERERERERDREKEREREREER--------------ER 758
Query: 1950 SRDGSRHPGSHHEDRAGHGHSADSSRQSGTRHTESSSRGQ--AASSHEQARSSAGERHGS 2007
R+ R E D R+ R E +G+ E+ R R G
Sbjct: 759 ERERERERERERERERERARERDKERER-QRDWEDKDKGRDDRREKREEIREDRNPRDG- 816
Query: 2008 HHQLQSADSSRHSGIGHGQASSAVRDSGHRGYSGSQASDSEGHSED-------------- 2053
H + +S R+ G S + R S R S SD+ +D
Sbjct: 817 HDERKSKKRYRNEG------SPSPRQSPKRRREHSPDSDAYNSGDDKNEKHRLLSQVVRP 870
Query: 2054 SDTQSVSAQGKAGPHQQSHKESARGQSGESSGRSGSFLYQVSTHEQSESTHGQSAPSTGG 2113
+++S+S Q KE R + S R Y+ ++ S+ + T
Sbjct: 871 QESRSLSPSHLTEDRQGRWKEEDRKPERKESSRR----YEEQELKEKVSSVDKQREQTEI 926
Query: 2114 RQGSHYDQAQDSSRHSASQEGQDTIRGHPGPSRGGR--QGSHQEQSVDRSGHSGSHHSHT 2171
+ S +AQD H S++ + + R H + + + +++ D G + T
Sbjct: 927 LESSRM-RAQDIIGHHQSEDRETSDRAHDENKKKAKIQKKPIKKKKEDDVGIERGNIETT 985
Query: 2172 TSQGRSDASRGQSGSRSASRKTYDKEQSGDGSRHSGSHHHEASSWADSSRHSLVGQGQSS 2231
+ G+ + + +S +K K+ GD S EA+ + R
Sbjct: 986 SEDGQVFSPKKGQKKKSIEKKR--KKSKGD----SDISDEEAAQQSKKKR---------- 1029
Query: 2232 GPRTS--RPRGSSVSQDSDSEGHSEDSERRSGSASRNHHGSAQEQSRDGSRHPRSHHEDR 2289
GPRT + V + G EDS+++ +A + + E D + + H
Sbjct: 1030 GPRTPPITTKEELVEMCNGKNGILEDSQKKEDTAFSDW---SDEDVPDRTEVTEAEHTAT 1086
Query: 2290 AGHGHSAESSRQSGTHHAENSSGGQAASSHEQARSSAGERHGSHHQQSADSSRHSGIGHG 2349
A S S S + A + ++ S + S + +
Sbjct: 1087 ATTPGSTPSPLSSLLPPPPPVATATATTVPATLAATTAAAATSFSTSAITISTSATPTNT 1146
Query: 2350 QASSAVRDSGHRGSSGSQASDSE-GHSEDSDTQSVSAHGQAGPHQQSHQESTRGRSAGRS 2408
++ + HR ++ E H D Q P Q S + RS
Sbjct: 1147 TNNTFANEDSHRKCHRTRVEKVETPHVTIEDAQ------HRKPMDQKRSSSLGSNRSNRS 1200
Query: 2409 GRSGSFLYQVSTHEQSESAHGRTGTSTGGRQGSHHKQARDSSRHSTSQEGQDTIHGHPGS 2468
SG ++SAH R+G GR+ H +RD + + +
Sbjct: 1201 HTSGRL-----RSPSNDSAH-RSGDDQSGRKRVLHSGSRDREKTKSLE------------ 1242
Query: 2469 SSGGRQGSHYEQLVDRSGHSGSHHSHTTSQGRSDASHGHSGSRSASRQTRNDEQSGDGSR 2528
G + S +QL S +TS R D S HS SR +S ++ S GS
Sbjct: 1243 -ITGERKSRIDQL------KRGEPSRSTSSDRQD-SRSHS-SRRSSPESDRQVHSRSGSF 1293
Query: 2529 HSGSRHHEASSRADSSGHSQVGQGQSEGPRTSRNWGSSFSQD---SDSQGHSEDSERWSG 2585
S R E D H + + + R R W +D + + + ER
Sbjct: 1294 DSRDRLQE----RDRYEHDRERERERRDTR-QREWDRDADKDWPRNRDRDRLRERERERE 1348
Query: 2586 SASRNHHGSAQEQL-RDGSRHPRSHQEDRAGHGHSADSSRQ-------SGTRHTQTSSGG 2637
R +E+L D R DR +S ++ R +++S
Sbjct: 1349 RDKRRDLDRERERLISDSVERDRDRDRDRTFESSQIESVKRCEAKLEGEHERDLESTSRD 1408
Query: 2638 QAASSHEQARSSAGERHGSHHQQSADSSRHSGIGHGQASSAVRDSGHRGYSGSQASDNEG 2697
A E+ G G +++ S R + G S + D H SG+ EG
Sbjct: 1409 SLALDKERMDKDLGSVQG--FEETNKSERTESLEAGDDESKL-DDAHSLGSGA----GEG 1461
Query: 2698 HSEDSDTQ 2705
+ SD +
Sbjct: 1462 YEPISDDE 1469
Score = 89.4 bits (220), Expect = 7e-17
Identities = 208/1116 (18%), Positives = 358/1116 (32%), Gaps = 114/1116 (10%)
Query: 2824 RSDASRGQSGSRSASRTTRNEEQSGDGSRHS--GSRHHEASTHADISRHSQAVQGQSEGS 2881
R RG+ R + + S G HS SRHH +S S+ ++Q S
Sbjct: 295 RDGKDRGRDFERQREKRDKPRSTSPAGQHHSPISSRHHSSS-----SQSGSSIQRHSPSP 349
Query: 2882 RRSRRQGSSVSQDSDSEGHSEDSERWSGSASRNHHGSAQEQLRDGSRHPRSHQEDRAGHG 2941
RR R S + S S S S + + R R H +R
Sbjct: 350 RRKRTPSPSYQRTLTPPLRRSASPYPSHSLSSPQRKQSPPRHRSPMREKGRHDHERTSQS 409
Query: 2942 HSADSSRQSGTRHTQT-SSGGQAASSHEQARSSAGE-------RHGSHHQQSADSSRHSG 2993
H R+ TR + + +EQ +SS+ + R G + + D+
Sbjct: 410 HDRRHERREDTRGKRDREKDSREEREYEQDQSSSRDHRDDREPRDGRDRRDARDTRDRRE 469
Query: 2994 IGHGQASSAVRDSGH-RGYSGSQASDNEGHSEDS--------DTQSVSAHGQAGSHQQSH 3044
+ + S +RDS R YS + S D + H + ++ +
Sbjct: 470 L---RDSRDMRDSREMRDYSRDTKESRDPRDSRSTRDAHDYRDREGRDTHRKEDTYPEES 526
Query: 3045 QESARGRSGETSGHSGSFLYQVSTHEQSESSHGWTGPSTRGR------QGSRHEQAQDSS 3098
+ R E S + + +SE + G S RGR +GSR +
Sbjct: 527 RSYGRNHLREESSRT-EIRNESRNESRSEIRNDRMGRS-RGRVPELPEKGSRGSRGSQID 584
Query: 3099 RHSASQYGQDTIRGHPGSSRGGRQGYHHEHSVDSSGHSGSHHSHTTSQGRSDASRGQSGS 3158
HS++ D+ SS R Y + D + S H R + R Q S
Sbjct: 585 SHSSNSNYHDSWETR--SSYPERDRYPERDNRDQARDSSFERRHGERDRRDNRERDQRPS 642
Query: 3159 RSASRTTRNEEQSGDSSRHSVSRHHEASTHADISRHSQAVQGQSEGSRRSRRQGSSVSQD 3218
RN+E D R E R + + + R R + ++
Sbjct: 643 SPIRHQGRNDELERDE------RREERRVDRVDDRRDERARERDRERERDRERERERERE 696
Query: 3219 SDSEGHSE-DSERWSGSASRNHRGSVQEQSRHGSRHPRSHHEDRAGHGHSADRSRQSGTR 3277
D E E + ER R +++ R R E +R R+ R
Sbjct: 697 RDREREKERELERERAREREREREKERDRERDRDRDHDRERERERERDREKEREREREER 756
Query: 3278 HAETSSGGQAASSHEQARSSPGERHGSRHQQSADSSRHSGIP-RGQASSAVRDSRHWGSS 3336
E + E+ R ER R +Q + G R + +R+ R+
Sbjct: 757 ERERERERERERERERERERARERDKERERQRDWEDKDKGRDDRREKREEIREDRN---- 812
Query: 3337 GSQASDSEGHSEESDTQSVSGHGQAGPHQQSHQ------ESARDRSGGRSGRSGSFLYQV 3390
+GH E + G P Q + +S SG L QV
Sbjct: 813 -----PRDGHDERKSKKRYRNEGSPSPRQSPKRRREHSPDSDAYNSGDDKNEKHRLLSQV 867
Query: 3391 STHEQSESAHGRTRTSTGRRQGSHHEQARDSSRHSASQ--EGQDTIRGHPGSSRRGRQGS 3448
++S S T RQG E+ R R +S+ E Q+ ++ Q
Sbjct: 868 VRPQESRSLSPSHLTED--RQGRWKEEDRKPERKESSRRYEEQELKEKVSSVDKQREQTE 925
Query: 3449 HYEQSVDRSGHSGSHHSHTTSQGRSDASRGQSGSRSASRQTRNDEQSGDGSRHSWSHHHE 3508
E S R+ HH S+ R + R ++ ++ + + +
Sbjct: 926 ILESSRMRAQDIIGHHQ---SEDRETSDRAHDENKKKAKIQKKPIKKKKEDDVGIERGNI 982
Query: 3509 ASTQADSSRHSQSGQGQSAGPRTSRNQGSSVSQDSDSQGHSEDSERWSGSASRNHRGSAQ 3568
+T D GQ P+ + + S + S+G S+ S+ + Q
Sbjct: 983 ETTSED---------GQVFSPKKGQKKKSIEKKRKKSKGDSDISDE---------EAAQQ 1024
Query: 3569 EQSRDGSRHPTSHHEDRAGHGHSAESSRQSGTHHAENSSGGQAASSHEQARSSAGERHGS 3628
+ + G R P ++ + ++ + E+++ + R+ E +
Sbjct: 1025 SKKKRGPRTPPITTKEELVEMCNGKNGILEDSQKKEDTAFSDWSDEDVPDRTEVTEAEHT 1084
Query: 3629 HHQQSADSSRHSGIGHGQASSAVRDSGHRGSSGSQASDSEGHSEDSDTQSVSAHGQAGPH 3688
+ S+ V + + A+ + + T +++ A P
Sbjct: 1085 ATATTPGSTPSPLSSLLPPPPPVATATATTVPATLAATTAAAATSFSTSAITISTSATPT 1144
Query: 3689 QQSHQESTRGRSAGRSGRSGSFLYQVSTHEQSESAHGRAGPSTGGRQGSRHEQARDSSRH 3748
++ S + R+ E+ E+ H + ++H + D R
Sbjct: 1145 NTTNNTFANEDSHRKCHRTRV--------EKVETPHVTI-------EDAQHRKPMDQKRS 1189
Query: 3749 SASQEGQDTIRGHPGSRRGGRQGSYHEQSVDRSGHSGSHHSHTTSQGRSDASHGQSGSRS 3808
S+ + S GR S S RSG S G D +S +
Sbjct: 1190 SSLGSNRSN-----RSHTSGRLRSPSNDSAHRSGDDQSGRKRVLHSGSRDREKTKSLEIT 1244
Query: 3809 ASRETRNEE-QSGDGSRHSGSRHHEASTQADSSRHSQSGQGESAGSRRSRRQGSSVSQD- 3866
R++R ++ + G+ SR + +S + DS HS + + R GS S+D
Sbjct: 1245 GERKSRIDQLKRGEPSRST------SSDRQDSRSHSSRRSSPESDRQVHSRSGSFDSRDR 1298
Query: 3867 -SDSEAYPEDSERRSESASRNHHGSSREQSRDGSRH 3901
+ + Y D ER E R+ +D R+
Sbjct: 1299 LQERDRYEHDRERERERRDTRQREWDRDADKDWPRN 1334
Score = 86.7 bits (213), Expect = 4e-16
Identities = 243/1302 (18%), Positives = 415/1302 (31%), Gaps = 170/1302 (13%)
Query: 2028 SSAVRDSGHRGYSGSQASDSEGHSEDSDTQSVSA----QGKAGPHQQSHKESARGQSGE- 2082
S ++R S S S +D T +VS+ Q + QS K+ R S
Sbjct: 209 SPSLRKSSKSPKRKSSPKSSSASKKDRKTSAVSSPLLDQQRNSKTNQSKKKGPRTPSPPP 268
Query: 2083 ------SSGRSGSFLYQVSTHEQSESTHGQSAPSTGGRQGSHYDQAQD-----------S 2125
+ G+ Y+V + ++ G+ RQ D+ + S
Sbjct: 269 PIPEDIALGKKYKEKYKVKDRIEEKTRDGKDRGRDFERQREKRDKPRSTSPAGQHHSPIS 328
Query: 2126 SRH--SASQEGQDTIRGHPGPSRGGRQGSHQEQSVDRSGHSGSHHSHTTSQGRSDASRGQ 2183
SRH S+SQ G R P P R + S S+ T R AS
Sbjct: 329 SRHHSSSSQSGSSIQRHSPSPRR-------------KRTPSPSYQRTLTPPLRRSASPYP 375
Query: 2184 SGSRSASRKTYDKEQSGDGSRHSGSHHHEASSWADSSRHSLVG--QGQSSGPRTSRPRGS 2241
S S S+ ++ + R G H HE +S + RH +G+ + SR
Sbjct: 376 SHSLSSPQRKQSPPRHRSPMREKGRHDHERTSQSHDRRHERREDTRGKRDREKDSREERE 435
Query: 2242 SVSQDSDSEGHSEDSERRSGSASRNHHGSA-----------------QEQSRDG--SRHP 2282
S S H +D E R G R+ + ++ SRD SR P
Sbjct: 436 YEQDQSSSRDHRDDREPRDGRDRRDARDTRDRRELRDSRDMRDSREMRDYSRDTKESRDP 495
Query: 2283 RSHHEDRAGHGHSAESSRQSGTHHAENSSGGQAAS---SHEQARSSAGERHGSHHQQSAD 2339
R R H + R TH E++ ++ S +H + SS E +S
Sbjct: 496 RDSRSTRDAHDYRDREGRD--THRKEDTYPEESRSYGRNHLREESSRTEIRNESRNESRS 553
Query: 2340 SSRHSGIGHGQASSAVRDSGHRGSSGSQASDSEGHSEDSDTQSVSAHGQAGPHQQSHQES 2399
R+ +G + V + +GS GS+ S + HS +S+ + P + + E
Sbjct: 554 EIRNDRMGRSRGR--VPELPEKGSRGSRGSQIDSHSSNSNYHDSWETRSSYPERDRYPE- 610
Query: 2400 TRGRSAGRSGRSGSFLYQVSTHEQSESAHGRTGTSTGGR-QGSHHKQARDSSRHSTSQEG 2458
R R SF + ++ ++ S+ R QG + + RD R +
Sbjct: 611 ---RDNRDQARDSSFERRHGERDRRDNRERDQRPSSPIRHQGRNDELERDERREERRVDR 667
Query: 2459 QDTIHGHPGSSSGGRQGSHYEQLVDRSGHSGSHHSHTTSQGRSDASHGHSGSRSASRQTR 2518
D + E+ +R R A R R+
Sbjct: 668 VDDRRDERARERDRERERDRERERERERERDREREKERELERERAR-----EREREREKE 722
Query: 2519 NDEQSGDGSRHSGSRHHEASSRADSSGHSQVGQGQSEGPRTSRNWGSSFSQDSDSQGHSE 2578
D + H R E + + + + E R + ++ +
Sbjct: 723 RDRERDRDRDHDRERERERERDREKEREREREERERERERERERERERERERERARERDK 782
Query: 2579 DSER---WSG-SASRNHHGSAQEQLRDGSRHPRSHQEDRAG----HGHSADSSRQSGTRH 2630
+ ER W R+ +E++R+ R+PR ++R + S RQS R
Sbjct: 783 ERERQRDWEDKDKGRDDRREKREEIRE-DRNPRDGHDERKSKKRYRNEGSPSPRQSPKRR 841
Query: 2631 TQTSSGGQAASSHEQARSSAGERHGSHHQQSADSSRHSGIGHGQASSAVRDSGHRGYSGS 2690
+ S A +S G+ H+ + R S D R
Sbjct: 842 REHSPDSDAYNS--------GDDKNEKHRLLSQVVRPQESRSLSPSHLTEDRQGRWKEED 893
Query: 2691 QASDNEGHSEDSDTQSVSAHGQAGSHQQSHQ---ESARGRSGETSGHSGSFLYQVSTHEQ 2747
+ + + S + Q + + Q+ ES+R R+ + GH +Q E
Sbjct: 894 RKPERKESSRRYEEQELKEKVSSVDKQREQTEILESSRMRAQDIIGH-----HQSEDRET 948
Query: 2748 SESSHGWTGPSTRGRQGSRHEQAQDSSRHSASQDGQDTIRGHPGSSRGGRQGYHHEHSVD 2807
S+ +H + + + Q +D RG +++
Sbjct: 949 SDRAHD---------ENKKKAKIQKKPIKKKKEDDVGIERG----------------NIE 983
Query: 2808 SSGHSGSHHSHTTSQGRSDASRGQSGSRSASRTTRNEEQSGDGSRHSGSRHHEASTHADI 2867
++ G S Q + + + S+ S + +EE + + G R +T ++
Sbjct: 984 TTSEDGQVFSPKKGQKKKSIEKKRKKSKGDSDIS-DEEAAQQSKKKRGPRTPPITTKEEL 1042
Query: 2868 SRHSQAVQGQSEGSRRSRRQGSSVSQDSDSEGHSEDSERWSGSASRNHHGSAQEQLRD-- 2925
G E S++ S D D +E +E +A+ GS L
Sbjct: 1043 VEMCNGKNGILEDSQKKEDTAFSDWSDEDVPDRTEVTEA-EHTATATTPGSTPSPLSSLL 1101
Query: 2926 ----------GSRHPRSHQEDRAGHGHSADSS----RQSGTRHTQTSSGGQAASSHEQAR 2971
+ P + A S +S S T T++ SH +
Sbjct: 1102 PPPPPVATATATTVPATLAATTAAAATSFSTSAITISTSATPTNTTNNTFANEDSHRKCH 1161
Query: 2972 SSAGERHGSHHQQSADSSRHSGIGHGQASSAVRDSGHRGYSGSQASDNEGHSEDSDTQSV 3031
+ E+ + H D+ + ++SS + +R ++ + S +D+
Sbjct: 1162 RTRVEKVETPHVTIEDAQHRKPMDQKRSSSLGSNRSNRSHTSGRL-----RSPSNDSAHR 1216
Query: 3032 SAHGQAGSHQQSH---QESARGRSGETSGHSGSFLYQVSTHEQSESSHGWTGPSTRGRQG 3088
S Q+G + H ++ + +S E +G S + Q+ E S S ++ RQ
Sbjct: 1217 SGDDQSGRKRVLHSGSRDREKTKSLEITGERKSRIDQLKRGEPSRS-------TSSDRQD 1269
Query: 3089 SRHEQAQDSSRHSASQYGQDTIRGHPGSSRGGRQGYHHEHSVDSSGHSGSHHSHTTSQGR 3148
SR ++ SS S Q + R Y H+ +
Sbjct: 1270 SRSHSSRRSSPESDRQVHSRSGSFDSRDRLQERDRYEHDRE-----RERERRDTRQREWD 1324
Query: 3149 SDASRGQSGSRSASRTTRNEEQSGDSSRHSVSRHHE------ASTHADISRHSQAVQGQS 3202
DA + +R R E + R + R E D R Q
Sbjct: 1325 RDADKDWPRNRDRDRLRERERERERDKRRDLDRERERLISDSVERDRDRDRDRTFESSQI 1384
Query: 3203 EGSRRSRRQGSSVSQDSDSEGHSEDSERWSGSASRNHRGSVQ 3244
E +R + + D E S DS GSVQ
Sbjct: 1385 ESVKRCEAKLEG-EHERDLESTSRDSLALDKERMDKDLGSVQ 1425
Score = 85.9 bits (211), Expect = 7e-16
Identities = 173/885 (19%), Positives = 300/885 (33%), Gaps = 118/885 (13%)
Query: 3153 RGQSGSRSASRTTRNEEQSGDSSRHSVSRHHEASTHA---DISRHSQAVQGQSEGSRRSR 3209
RG+ S + R+ E +GD ++ + T + S V+ +S R
Sbjct: 66 RGKGYSSNYRRSP--ERPTGDLRERMKNKRQDVDTEPQKRNTEESSSPVRKESSRGRHRE 123
Query: 3210 RQGSSVSQDSDSEGHSEDSERWSGSASRNHRGSVQEQSRHGSRHPRSHHEDRAGHGHSAD 3269
++ ++++ E E+ E W + + G + + H S R
Sbjct: 124 KEDIKITKERTPESEEENVE-WETNRDDSDNGDIN----YDYVHELSLEMKRQKIQRELM 178
Query: 3270 RSRQSGTRHAETSSGGQAASSHEQARSSPGERHGSRHQQSADSSRHSGIPRGQASSAVRD 3329
+ Q E + S E RS R +S+ S + P+ +SSA +
Sbjct: 179 KLEQENMEKREEIIIKKEVSP-EVVRSKLSPSPSLR--KSSKSPKRKSSPK--SSSASKK 233
Query: 3330 SRHWGSSGSQASDSEGHSEESDTQSVSGHGQAGPHQQSHQESARDRSGGRSGRSGSFLYQ 3389
R + S D + +S+ + ++ G P ++ A G+ Y+
Sbjct: 234 DRKTSAVSSPLLDQQRNSKTNQSKK-KGPRTPSPPPPIPEDIAL-------GKKYKEKYK 285
Query: 3390 VSTHEQSESAHGRTRTSTGRRQ-------------GSHHEQARDSSRHSASQEGQDTIRG 3436
V + ++ G+ R RQ G HH S HS+S + +I+
Sbjct: 286 VKDRIEEKTRDGKDRGRDFERQREKRDKPRSTSPAGQHHSPI-SSRHHSSSSQSGSSIQR 344
Query: 3437 HPGSSRRGRQGSHYEQSVDRSGHSGSHHSHTTSQGRSDASRGQSGSRSASRQTRNDEQSG 3496
H S RR R S S+ T R AS S S S+ ++ ++ +
Sbjct: 345 HSPSPRRKRTPSP------------SYQRTLTPPLRRSASPYPSHSLSSPQRKQSPPRHR 392
Query: 3497 DGSRHSWSHHHEASTQADSSRHS--QSGQGQSAGPRTSRNQGSSVSQDSDSQGHSEDSER 3554
R H HE ++Q+ RH + +G+ + SR + S S+ H +D E
Sbjct: 393 SPMREKGRHDHERTSQSHDRRHERREDTRGKRDREKDSREEREYEQDQSSSRDHRDDREP 452
Query: 3555 WSGSASRNHRGSA-----------------QEQSRDG--SRHPTSHHEDRAGHGHSAESS 3595
G R+ R + ++ SRD SR P R H +
Sbjct: 453 RDGRDRRDARDTRDRRELRDSRDMRDSREMRDYSRDTKESRDPRDSRSTRDAHDYRDREG 512
Query: 3596 RQSGTHHAENSSGGQAAS---SHEQARSSAGERHGSHHQQSADSSRHSGIGHGQASSAVR 3652
R TH E++ ++ S +H + SS E +S R+ +G + V
Sbjct: 513 RD--THRKEDTYPEESRSYGRNHLREESSRTEIRNESRNESRSEIRNDRMGRSRGR--VP 568
Query: 3653 DSGHRGSSGSQASDSEGHSEDS------DTQSVSAHGQAGPHQQS------------HQE 3694
+ +GS GS+ S + HS +S +T+S P + + H E
Sbjct: 569 ELPEKGSRGSRGSQIDSHSSNSNYHDSWETRSSYPERDRYPERDNRDQARDSSFERRHGE 628
Query: 3695 STRGRSAGRSGRSGSFLYQVSTHEQSESAHGRAGPSTGGRQGSRHEQARDSSRHSASQEG 3754
R + R R S + +++ E R R E+AR+ R
Sbjct: 629 RDRRDNRERDQRPSSPIRHQGRNDELERDERREERRVDRVDDRRDERARERDRERERDRE 688
Query: 3755 QDTIRGHPGSRRGGRQGSYH---------EQSVDRSGHSGSHHSHTTSQGRSDASHGQSG 3805
++ R R ++ E+ +R H + R + +
Sbjct: 689 RERERERERDREREKERELERERAREREREREKERDRERDRDRDHDRERER-ERERDREK 747
Query: 3806 SRSASRETRNEEQSGDGSRH-SGSRHHEASTQADSSRHSQSGQGESAGSRRSRRQGSSVS 3864
R RE R E+ + R R E + + D R Q + R RR+
Sbjct: 748 EREREREERERERERERERERERERERERARERDKERERQRDWEDKDKGRDDRREKREEI 807
Query: 3865 QDSDSEAYPEDSERRSESASRNHHGSS--------REQSRDGSRHPGSSHRDTASHVQSS 3916
++ + D ER+S+ RN S RE S D + ++ + S
Sbjct: 808 REDRNPRDGHD-ERKSKKRYRNEGSPSPRQSPKRRREHSPDSDAYNSGDDKNEKHRLLSQ 866
Query: 3917 PVQSDSSTAKEHGHFSSLSQDSAYHSGIQSRGSPHSSSSYHYQSE 3961
V+ S + H L++D + R SS Y+ +
Sbjct: 867 VVRPQESRSLSPSH---LTEDRQGRWKEEDRKPERKESSRRYEEQ 908
Score = 85.1 bits (209), Expect = 1e-15
Identities = 234/1237 (18%), Positives = 409/1237 (33%), Gaps = 176/1237 (14%)
Query: 90 RKENLPISGHKHRKHSHHDKHEDNKQEENKENRKRPSSLERRNNRKGNKGRSKSPRETGG 149
RK++ P R+ HD HE Q ++ + ERR + +G + R K RE
Sbjct: 384 RKQSPPRHRSPMREKGRHD-HERTSQSHDRRH-------ERREDTRGKRDREKDSREERE 435
Query: 150 KRHESSSEKKERKGYSPTHREEEYGKNHHNSSKKEKNKTENTRLGDNRKRLSERLEEKED 209
+ SS + R P +++ +TR +R+ L + + ++
Sbjct: 436 YEQDQSSSRDHRDDREP-------------RDGRDRRDARDTR---DRRELRDSRDMRDS 479
Query: 210 NEEGVYDYENTGRMTQKWIQSGHIATYYTIQD--EAYDTTDSLLEENKIYERSRSSDGKS 267
E Y + + +S A Y ++ + + D+ EE++ Y R+ + S
Sbjct: 480 REMRDYSRDTKESRDPRDSRSTRDAHDYRDREGRDTHRKEDTYPEESRSYGRNHLREESS 539
Query: 268 SSQV-NRSRHENTSQVPLQESRTRKRRGSRVSQDRDSEGHSEDSERHSGSASRNHHGSAW 326
+++ N SR+E+ S++ + R + RG S S+ S S++ N+H S W
Sbjct: 540 RTEIRNESRNESRSEI--RNDRMGRSRGRVPELPEKGSRGSRGSQIDSHSSNSNYHDS-W 596
Query: 327 EQSRDGSRHPRSHDEDRASHGHSADSSRQSG--TRHAETSSRGQTASSHEQARSSPGERH 384
E S +P + DR + D +R S RH E R +Q SSP
Sbjct: 597 ETR---SSYP---ERDRYPERDNRDQARDSSFERRHGERDRRDN--RERDQRPSSPIRHQ 648
Query: 385 GSGHQQSADSSRHSATGRGQASSAVSDRGHRGSSGSQASDSEGHSENSDTQSVSGHGKAG 444
G + D R R D R + D E E + +
Sbjct: 649 GRNDELERDERREER--RVDRVDDRRDERARERDRERERDRERERERERERDREREKERE 706
Query: 445 LRQQSHQESTRGRSGERSGRSGSSLYQVSTHEQPDSAHGRTGTSTGGRQGSHHEQARDSS 504
L ++ +E R R ER + H++ R+
Sbjct: 707 LERERAREREREREKERDRERD--------------------------RDRDHDRERERE 740
Query: 505 RHSASQEGQDTIRGHPGSSRGGRQGSHHEQSVNRSGHSGSHHSHTTSQGRSDASHGQSGS 564
R ++ ++ R R + E+ R + D G+
Sbjct: 741 RERDREKEREREREERERERERERERERERERERERARERDKERERQRDWEDKDKGRDDR 800
Query: 565 RSASRQTRNEEQSGDGTRHSGSRHHEASSQADSSRHSQVGQGQSSGPRTSRNQGSSVSQD 624
R + R + DG H E S+ R+ G S PR S + S D
Sbjct: 801 REKREEIREDRNPRDG-------HDERKSK---KRYRNEG---SPSPRQSPKRRREHSPD 847
Query: 625 SDSQGHSEDSERWSGSASRNHHGSAQEQSRDGSRHPRSHH--EDRAGHGHSAD--SSRKS 680
SD+ +D + H +Q SR H EDR G D RK
Sbjct: 848 SDAYNSGDDK-------NEKHRLLSQVVRPQESRSLSPSHLTEDRQGRWKEEDRKPERKE 900
Query: 681 GTRHTQNSSSGQAASSHEQARSSAGERHGSRHQLQSADSSRHSGTGHGQASSAVRDSGHR 740
+R + + SS ++ R SR +++ D H + + S D +
Sbjct: 901 SSRRYEEQELKEKVSSVDKQREQTEILESSR--MRAQDIIGHHQSEDRETSDRAHDENKK 958
Query: 741 GSSGSQATDSEGHSED-----SDTQSVSGHGQAGHHQQSHQESARDRSGERSRRSGSFLY 795
+ + + +D + ++ S GQ S ++ + +S E+ R+
Sbjct: 959 KAKIQKKPIKKKKEDDVGIERGNIETTSEDGQV----FSPKKGQKKKSIEKKRKKSKGDS 1014
Query: 796 QVSTHKQSESSHGWTGPSTGVRQGSHHEQARDNSRHSASQDGQDTIRGHPGSSRRGRQGS 855
+S + ++ S GP T N ++ +D Q
Sbjct: 1015 DISDEEAAQQSKKKRGPRTPPITTKEELVEMCNGKNGILEDSQK-------KEDTAFSDW 1067
Query: 856 HHEQSVDRSGHSGSHHSHTTSQGRSDASRGQSGSRSASRTTRNEEQSRDGSRHSGSRHHE 915
E DR+ + + H+ T + + G + S +S + + +
Sbjct: 1068 SDEDVPDRTEVTEAEHTATAT------TPGSTPSPLSSLLPPPPPVATATATTVPATLAA 1121
Query: 916 ASSHADISRHSQAGQGQSEGSRTSRRQGSSVSQDSDSEGHSEDSER-------WSGSASR 968
++ A S + A + + T+ + ++DS + H E+ + R
Sbjct: 1122 TTAAAATSFSTSAITISTSATPTNTTNNTFANEDSHRKCHRTRVEKVETPHVTIEDAQHR 1181
Query: 969 NHRGSAQEQSRHGSRHPRSHHEDRAGHGHSADSSRQSGTPHAETSSGGQA---ASSHEQA 1025
+ S +R RSH R S DS+ +SG + SG + + S ++
Sbjct: 1182 KPMDQKRSSSLGSNRSNRSHTSGRL-RSPSNDSAHRSG----DDQSGRKRVLHSGSRDRE 1236
Query: 1026 RSSPGERHGSRHQQSADSSRHSGIPRRQASSAVRDS-GHWGSSGSQASDSEGHSEESDTQ 1084
++ E G R + R G P R SS +DS H S SD + HS
Sbjct: 1237 KTKSLEITGERKSRIDQLKR--GEPSRSTSSDRQDSRSHSSRRSSPESDRQVHS------ 1288
Query: 1085 SVSGHGQDGPHQQSHQESARDWSGGRSGRSGSFIYQVSTHEQSESAHGRTRTSTGRRQGS 1144
RSGSF + E+ H R R RR
Sbjct: 1289 ----------------------------RSGSFDSRDRLQERDRYEHDRER-ERERRDTR 1319
Query: 1145 HHEQARDSSRHSASQEGQDTIRAHPGSRRGGRQGSHHEQSVDRSGHSGSHHSHTTSQGRS 1204
E RD+ + +D +R R ++ + +DR S + R
Sbjct: 1320 QREWDRDADKDWPRNRDRDRLRERERERERDKR-----RDLDRERERLISDSVERDRDR- 1373
Query: 1205 DASHGQSGSRSASRQTRKDKQSGDGSRHSGSRHHEAASWADSSRHSQVGQEQSSGSRTSR 1264
D S+ S + + K G+ R S ++ + +G Q T++
Sbjct: 1374 DRDRTFESSQIESVKRCEAKLEGEHERDLESTSRDSLALDKERMDKDLGSVQGF-EETNK 1432
Query: 1265 HQGSSVSQDSDSERHSDDSERLSGSASRNHHGSSREQ 1301
+ + + D E DD+ L A + S ++
Sbjct: 1433 SERTESLEAGDDESKLDDAHSLGSGAGEGYEPISDDE 1469
Score = 80.9 bits (198), Expect = 2e-14
Identities = 225/1238 (18%), Positives = 400/1238 (32%), Gaps = 197/1238 (15%)
Query: 2698 HSEDSDTQSVSAHGQAGSHQQSHQESARGRSGETSGHSGSFLYQVSTHEQSESSHGWTGP 2757
H ++ S+ Q+GS Q H S R + + + + + SH + P
Sbjct: 323 HHSPISSRHHSSSSQSGSSIQRHSPSPRRKRTPSPSYQRTLTPPLRRSASPYPSHSLSSP 382
Query: 2758 STRGRQGSRHEQAQDSSRHSASQDGQDTIRGHPGSSRGGRQGYHHEHSVDSSGHSGSHHS 2817
++ Q RH + R+ H+H S H H
Sbjct: 383 ----------QRKQSPPRHRSPM----------------REKGRHDHERTSQSHDRRHE- 415
Query: 2818 HTTSQGRSDASRGQSGSRSASRTTRNEEQSGDGSRHSGSRHHEASTHADISRHSQAVQGQ 2877
R + +RG+ SR R EQ S SR H R + +
Sbjct: 416 ------RREDTRGKRDREKDSREEREYEQD-----QSSSRDHRDDREPRDGRDRR--DAR 462
Query: 2878 SEGSRRSRRQGSSVSQDSDSEGHSEDSERWSGSASRNHHGSAQEQLRDGSRHPRSHQEDR 2937
RR R + + +S D++ SR PR + R
Sbjct: 463 DTRDRRELRDSRDMRDSREMRDYSRDTKE--------------------SRDPRDSRSTR 502
Query: 2938 AGHGH----SADSSRQSGTRHTQTSSGGQAASSHEQARSSAGERHGSHHQQSADSSRHSG 2993
H + D+ R+ T ++ S G+ +H + SS E +S R+
Sbjct: 503 DAHDYRDREGRDTHRKEDTYPEESRSYGR---NHLREESSRTEIRNESRNESRSEIRNDR 559
Query: 2994 IGHGQASSAVRDSGHRGYSGSQASDNEGHSEDSDTQSVSAHGQAGSHQQSHQESAR--GR 3051
+ G++ V + +G GS+ S + HS +S+ + + + S+ E R R
Sbjct: 560 M--GRSRGRVPELPEKGSRGSRGSQIDSHSSNSN------YHDSWETRSSYPERDRYPER 611
Query: 3052 SGETSGHSGSFLYQVSTHEQSESSHGWTGPSTRGR-QGSRHEQAQDSSRHSASQYGQDTI 3110
SF + ++ ++ PS+ R QG E +D R D
Sbjct: 612 DNRDQARDSSFERRHGERDRRDNRERDQRPSSPIRHQGRNDELERDERREERRVDRVDDR 671
Query: 3111 RGHPGSSRGGRQGYHHEHSVDSSGHSGSHHSHTTSQGRSDASRGQSGSRSASRTTRNEEQ 3170
R R + E + + R ++ R R + +
Sbjct: 672 RDERARERDRERERDRERE-----RERERERDREREKERELERERAREREREREKERDRE 726
Query: 3171 SGDSSRHSVSRHHEASTHADISRHSQAVQGQSEGSRRSRRQGSSVSQDSDSEGHSEDSER 3230
H R E + R + + + E R R+ + + ++ ER
Sbjct: 727 RDRDRDHDRERERERERDREKEREREREERERERERERERERERERERERARERDKERER 786
Query: 3231 ---WSG-SASRNHRGSVQEQSRHGSRHPRSHHEDRAGHGHSADRSRQSGTRHAETSSGGQ 3286
W R+ R +E+ R R+PR H++R S R R G+ S +
Sbjct: 787 QRDWEDKDKGRDDRREKREEIRE-DRNPRDGHDER----KSKKRYRNEGSPSPRQSPKRR 841
Query: 3287 AASSHEQARSSPGERHGSRHQQSADSSRHSGIPRGQASSAVRDSRHWGSSGSQASDSEGH 3346
S + + G+ +H+ S + R Q S ++ S D +G
Sbjct: 842 REHSPDSDAYNSGDDKNEKHRLL------SQVVRPQESRSL-------SPSHLTEDRQGR 888
Query: 3347 SEESDTQSVSGHGQAGPHQQSHQESARDRSGGRSGRSGSFLYQVSTHEQSESAHGRTRTS 3406
+E D + +ES+R Y+ ++ S+ + R
Sbjct: 889 WKEED------------RKPERKESSR-------------RYEEQELKEKVSSVDKQREQ 923
Query: 3407 TGRRQGSHHEQARDSSRHSASQEGQDTIRGHPGSSRRGR--QGSHYEQSVDRSGHSGSHH 3464
T + S +A+D H S++ + + R H + ++ + + ++ D G +
Sbjct: 924 TEILESS-RMRAQDIIGHHQSEDRETSDRAHDENKKKAKIQKKPIKKKKEDDVGIERGNI 982
Query: 3465 SHTTSQGRSDASRGQSGSRSASRQTRNDEQSGDGSRHSWSHHHEASTQADSSRHSQSGQG 3524
T+ G+ + + G + S + + + GD + ++++ S+ +G
Sbjct: 983 ETTSEDGQVFSPK--KGQKKKSIEKKRKKSKGDSD----------ISDEEAAQQSKKKRG 1030
Query: 3525 QSAGPRTSRNQGSSVSQDSDSQGHSEDSERWSGSASRNHRGSAQEQSRDGSRHPTSHHED 3584
P T++ + V + G EDS++ +A + + E D + + H
Sbjct: 1031 PRTPPITTKEE--LVEMCNGKNGILEDSQKKEDTAFSDW---SDEDVPDRTEVTEAEHTA 1085
Query: 3585 RAGHGHSAESSRQS-----------------GTHHAENSSGGQAASSHEQARSSAGERHG 3627
A S S S T A ++ + S+ S++
Sbjct: 1086 TATTPGSTPSPLSSLLPPPPPVATATATTVPATLAATTAAAATSFSTSAITISTSATPTN 1145
Query: 3628 SHHQQSADSSRHSGIGHGQASS------AVRDSGHRGSSGSQASDSEGHSEDSDTQSVSA 3681
+ + A+ H + + D+ HR + S S G + + +
Sbjct: 1146 TTNNTFANEDSHRKCHRTRVEKVETPHVTIEDAQHRKPMDQKRSSSLGSNRSNRS----- 1200
Query: 3682 HGQAGPHQQSHQESTRGRSAGRSGRSGSFLYQVSTHEQSESAHGRAGPSTGGRQGSRHEQ 3741
H S SA RSG S +V + ++ TG R+ +
Sbjct: 1201 ------HTSGRLRSPSNDSAHRSGDDQSGRKRVLHSGSRDREKTKSLEITGERKSRIDQL 1254
Query: 3742 ARDSSRHSASQEGQDTIRGHPGSRRGGRQGSYHEQSVDRSGH--SGSHHSHTTSQGRSDA 3799
R S S + QD+ R H SRR + DR H SGS S Q R
Sbjct: 1255 KRGEPSRSTSSDRQDS-RSH-SSRRSSPES-------DRQVHSRSGSFDSRDRLQERDRY 1305
Query: 3800 SHGQSGSRSASRETRNEEQSGDGSRHSGSRHHEASTQADSSRHSQSGQGESAGSRRSRRQ 3859
H + R R+TR E D + R+ + + R + + R R
Sbjct: 1306 EHDRERERE-RRDTRQREWDRDADK-DWPRNRDRDRLRERERERERDKRRDLDRERERLI 1363
Query: 3860 GSSVSQDSDSEAYPEDSERRSESASRNHHGSSREQSRD 3897
SV +D D + + ES R E RD
Sbjct: 1364 SDSVERDRDRDRDRTFESSQIESVKRCEAKLEGEHERD 1401
Score = 77.4 bits (189), Expect = 3e-13
Identities = 180/972 (18%), Positives = 324/972 (33%), Gaps = 105/972 (10%)
Query: 2819 TTSQGRSDASRGQSGSRSASRTTRNEEQSGDGSRHSGSRHHEASTHADISR---HSQAVQ 2875
++S R ++SRG+ + + T+ + + + S + DI+ H +++
Sbjct: 108 SSSPVRKESSRGRHREKEDIKITKERTPESEEENVEWETNRDDSDNGDINYDYVHELSLE 167
Query: 2876 GQSEGSRRSRRQGSSVSQDSDSE-----GHSEDSERWSGSASRNHHGSAQEQLRDGSRHP 2930
+ + +R + + + E S + R S S + S++ R S P
Sbjct: 168 MKRQKIQRELMKLEQENMEKREEIIIKKEVSPEVVRSKLSPSPSLRKSSKSPKRKSS--P 225
Query: 2931 RSHQEDRAGHGHSADSS----RQSGTRHTQTSSGGQAASSHEQARS---SAGERHGSHHQ 2983
+S + SA SS +Q ++ Q+ G S + G+++ ++
Sbjct: 226 KSSSASKKDRKTSAVSSPLLDQQRNSKTNQSKKKGPRTPSPPPPIPEDIALGKKYKEKYK 285
Query: 2984 --QSADSSRHSGIGHGQASSAVRDSGHRGYSGSQASDNEGHSEDSDTQSVSAHGQAGSHQ 3041
+ G G+ R+ + S S A H ++ S+ Q+GS
Sbjct: 286 VKDRIEEKTRDGKDRGRDFERQREKRDKPRSTSPAGQ---HHSPISSRHHSSSSQSGSSI 342
Query: 3042 QSHQESARGRSGETSGHSGSFLYQVSTHEQSESSHGWTGPSTRG---------RQGSRHE 3092
Q H S R + + + + + SH + P + R+ RH+
Sbjct: 343 QRHSPSPRRKRTPSPSYQRTLTPPLRRSASPYPSHSLSSPQRKQSPPRHRSPMREKGRHD 402
Query: 3093 QAQDSSRHSASQYGQDTIRGHPGSSRGGRQGYHHEHSVDSSGHSGSHHSHTTSQGRSDA- 3151
+ S H ++ RG + R+ +E SS + R DA
Sbjct: 403 HERTSQSHDRRHERREDTRGKRDREKDSREEREYEQDQSSSRDHRDDREPRDGRDRRDAR 462
Query: 3152 ----------SRGQSGSRSASRTTRNEEQSGD--SSRHSVSRHHEASTHA-DISRHSQAV 3198
SR SR +R+ ++S D SR + H D R
Sbjct: 463 DTRDRRELRDSRDMRDSREMRDYSRDTKESRDPRDSRSTRDAHDYRDREGRDTHRKEDTY 522
Query: 3199 QGQSEGSRRSRRQGSSVSQDSDSEGHSEDSERWSGSASRNHRGSVQEQSRHGSRHPRSHH 3258
+S R+ + S + +E +E RG V E GSR R
Sbjct: 523 PEESRSYGRNHLREESSRTEIRNESRNESRSEIRNDRMGRSRGRVPELPEKGSRGSRGSQ 582
Query: 3259 EDRAGHGHSADRSRQSGTRHAETSSGGQAASSHEQARSSPGER-HGSRHQQSADSSRHSG 3317
D + S ++ + + E + + +QAR S ER HG R +
Sbjct: 583 IDSHSSNSNYHDSWETRSSYPERDRYPER-DNRDQARDSSFERRHGERDR---------- 631
Query: 3318 IPRGQASSAVRDSRHWGSSGSQASDSEGHSEESDTQSVSGHGQAGPHQQSHQESARDRSG 3377
RD+R S +G ++E + + E AR+R
Sbjct: 632 ----------RDNRERDQRPSSPIRHQGRNDELERDERREERRVDRVDDRRDERARERDR 681
Query: 3378 GRSGRSGSFLYQVSTHEQSESAHGRTRTSTGRRQGSHHEQARDSSRHSASQEG--QDTIR 3435
R + + E R R R+ E+AR+ R + +D R
Sbjct: 682 ER---------ERDRERERERERERDREREKERE-LERERAREREREREKERDRERDRDR 731
Query: 3436 GHPGSSRRGRQ-GSHYEQSVDRSGHSGSHHSHTTSQGRSDASRGQSGSRSASRQTRNDEQ 3494
H R R+ E+ +R + + R ++ R R+ + D +
Sbjct: 732 DHDRERERERERDREKEREREREERERERERERERERERERERERARERDKERERQRDWE 791
Query: 3495 SGDGSRHSWSHHHEASTQADSSRHSQSGQGQSAGPRTSRNQGSSVSQDSDS--QGHSEDS 3552
D R E + R+ + G + + RN+GS + S + HS DS
Sbjct: 792 DKDKGR---DDRREKREEIREDRNPRDGHDERKSKKRYRNEGSPSPRQSPKRRREHSPDS 848
Query: 3553 ERWSGSASRN--HRGSAQEQSRDGSRHPTSHHEDRAGHGHSAESSRQSGTHHAENSSGGQ 3610
+ ++ +N HR +Q SR + H G E R+ E+S +
Sbjct: 849 DAYNSGDDKNEKHRLLSQVVRPQESRSLSPSHLTEDRQGRWKEEDRK--PERKESSRRYE 906
Query: 3611 AASSHEQARSSAGERHGSHHQQSADSSRHSGIGHGQASS-AVRDSGH---RGSSGSQASD 3666
E+ S +R + +S+ IGH Q+ D H + + Q
Sbjct: 907 EQELKEKVSSVDKQREQTEILESSRMRAQDIIGHHQSEDRETSDRAHDENKKKAKIQKKP 966
Query: 3667 SEGHSED------SDTQSVSAHGQA-GPHQQSHQESTRGRSAGRSGRSGSFLYQVSTHEQ 3719
+ ED + ++ S GQ P + ++S + G S +S E
Sbjct: 967 IKKKKEDDVGIERGNIETTSEDGQVFSPKKGQKKKSIEKKRKKSKGDS-----DISDEEA 1021
Query: 3720 SESAHGRAGPST 3731
++ + + GP T
Sbjct: 1022 AQQSKKKRGPRT 1033
Score = 63.2 bits (152), Expect = 5e-09
Identities = 147/787 (18%), Positives = 256/787 (32%), Gaps = 110/787 (13%)
Query: 87 ESTRKENLPISGHKHRKHSHHDKHEDNKQEENKENRKRPSSLERRNNRKGNKGRSKSPRE 146
E R+ K R+ E ++ E + +R+R + R+ + R +
Sbjct: 690 ERERERERDREREKERELERERAREREREREKERDRERDRDRDHDRERERERERDRE--- 746
Query: 147 TGGKRHESSSEKKERKGYSPTHREEEYGKNHHNSSKKEKNKTENTRLGDNRKRLSERLEE 206
K E E++ER+ RE E + + +++K + D K +R E+
Sbjct: 747 ---KEREREREERERERERERERERERERERERARERDKERERQRDWEDKDKGRDDRREK 803
Query: 207 KEDNEEGVYDYENTGRMTQKWIQSGHIATYYTIQDEAYDTTDSLLEENKIYERSRSSDGK 266
+E+ E + + GH + + + E S SD
Sbjct: 804 REEIRE------------DRNPRDGHDERKSKKRYRNEGSPSPRQSPKRRREHSPDSDAY 851
Query: 267 SSSQVNRSRHENTSQVPLQESRTRKRRGSRVSQDRDSEGHSEDSERHSGSASRNHHGSAW 326
+S +H SQV ++ +R S +++DR ED + +SR +
Sbjct: 852 NSGDDKNEKHRLLSQV-VRPQESRSLSPSHLTEDRQGRWKEEDRKPERKESSRRYEEQEL 910
Query: 327 EQSRDGSRHPRSHDEDRASH--------GHSADSSRQSGTR-HAETSSRG--QTASSHEQ 375
++ R E S GH R++ R H E + Q ++
Sbjct: 911 KEKVSSVDKQREQTEILESSRMRAQDIIGHHQSEDRETSDRAHDENKKKAKIQKKPIKKK 970
Query: 376 ARSSPGERHGSGHQQSADSSRHSATGRGQASSAVSDRGHRGSSGSQASDSEGHSENSDTQ 435
G G+ S D S +GQ ++ + + S SD E ++ +
Sbjct: 971 KEDDVGIERGNIETTSEDGQVFSPK-KGQKKKSIEKKRKKSKGDSDISDEEAAQQSKKKR 1029
Query: 436 SVSG-------------HGKAGLRQQSHQ------------------ESTRGRSGERSGR 464
+GK G+ + S + E T +
Sbjct: 1030 GPRTPPITTKEELVEMCNGKNGILEDSQKKEDTAFSDWSDEDVPDRTEVTEAEHTATATT 1089
Query: 465 SGSSLYQVST-HEQPDSAHGRTGTSTGGRQGSHHEQARDSSRHSASQEGQDTIRGHPGSS 523
GS+ +S+ P T T+ + A S SA + ++
Sbjct: 1090 PGSTPSPLSSLLPPPPPVATATATTVPATLAATTAAAATSFSTSAITISTSATPTNTTNN 1149
Query: 524 RGGRQGSH---HEQSVNR--SGH---SGSHHSHTTSQGRSDA--------SHGQSGSRSA 567
+ SH H V + + H + H Q RS + SH RS
Sbjct: 1150 TFANEDSHRKCHRTRVEKVETPHVTIEDAQHRKPMDQKRSSSLGSNRSNRSHTSGRLRSP 1209
Query: 568 SRQTRN---EEQSG-DGTRHSGSRHHE--ASSQADSSRHSQVGQGQSSGPRTSRNQGSSV 621
S + + ++QSG HSGSR E S + R S++ Q + P S +
Sbjct: 1210 SNDSAHRSGDDQSGRKRVLHSGSRDREKTKSLEITGERKSRIDQLKRGEPSRSTSSDRQD 1269
Query: 622 SQDSDSQGHSEDSERWSGSASRNHHGSAQEQSRDGSRHPRSHHEDRAGHGHSADSSRKSG 681
S+ S+ S +S+R S S + + Q RD H R +R R +
Sbjct: 1270 SRSHSSRRSSPESDRQVHSRSGSFDSRDRLQERDRYEHDRERERER----------RDTR 1319
Query: 682 TRHTQNSSSGQAASSHEQARSSAGERHGSRHQLQSADSSRHSGTGHGQASSAVRDSGHRG 741
R + + ++ R ER R + + D R + DS R
Sbjct: 1320 QREWDRDADKDWPRNRDRDRLRERERERERDKRRDLDRER---------ERLISDSVER- 1369
Query: 742 SSGSQATDSEGHSEDSDTQSVS--GHGQAGHHQQSHQESARDRSGERSRRSGSFLYQVST 799
+ D + E S +SV G H++ + ++RD R L V
Sbjct: 1370 ---DRDRDRDRTFESSQIESVKRCEAKLEGEHERDLESTSRDSLALDKERMDKDLGSVQG 1426
Query: 800 HKQSESS 806
+++ S
Sbjct: 1427 FEETNKS 1433
Score = 53.5 bits (127), Expect = 4e-06
Identities = 75/341 (21%), Positives = 114/341 (33%), Gaps = 31/341 (9%)
Query: 3652 RDSGHRGSSGSQASDSEGHSEDSDTQSVSAHGQAGPHQQSHQESTRGRSAGRSGRSGSFL 3711
R + G S S S S+ H + +++ S + RS S
Sbjct: 315 RSTSPAGQHHSPISSRHHSSSSQSGSSIQRHSPSPRRKRTPSPSYQRTLTPPLRRSASPY 374
Query: 3712 --YQVSTHEQSESAHGRAGPSTGGRQGSRHEQARDSSRHSASQEGQDTIRGHPGSRRGGR 3769
+ +S+ ++ +S P R+ RH+ R S H E ++ RG + R
Sbjct: 375 PSHSLSSPQRKQSPPRHRSPM---REKGRHDHERTSQSHDRRHERREDTRGKRDREKDSR 431
Query: 3770 QGSYHEQSVDRSGHSGSHHSHTTSQGRSDASHGQSGSRSASRETRNEEQSGDGSRHSGSR 3829
+ +EQ S H R D R +R+TR+ + D SR
Sbjct: 432 EEREYEQD------QSSSRDH-----RDDREPRDGRDRRDARDTRDRRELRDSRDMRDSR 480
Query: 3830 H-HEASTQADSSRHSQSGQGESAGSRRSRRQGSSVSQDSDSEAYPEDSERRSESASRNH- 3887
+ S SR + + R+G + D+ YPE+S S RNH
Sbjct: 481 EMRDYSRDTKESRDPRDSRSTRDAHDYRDREGRDTHRKEDT--YPEESR----SYGRNHL 534
Query: 3888 -HGSSREQSRDGSRHPGSSH----RDTASHVQSSPVQSDSSTAKEHGHFSSLSQDSAYHS 3942
SSR + R+ SR+ S R S + + S S S +S YH
Sbjct: 535 REESSRTEIRNESRNESRSEIRNDRMGRSRGRVPELPEKGSRGSRGSQIDSHSSNSNYHD 594
Query: 3943 GIQSRGSPHSSSSYHYQSEGTERQKGQSGLVWRHGSYGSAD 3983
++R S Y Q S RHG D
Sbjct: 595 SWETRSSYPERD--RYPERDNRDQARDSSFERRHGERDRRD 633
Score = 47.4 bits (111), Expect = 3e-04
Identities = 112/590 (18%), Positives = 197/590 (33%), Gaps = 68/590 (11%)
Query: 87 ESTRKENLPISGHKHRKHSHHDKH-EDNKQEENKEN---RKRPSSLERRNN---RKGN-- 137
ES+R I GH H D+ D +ENK+ +K+P ++ ++ +GN
Sbjct: 928 ESSRMRAQDIIGH----HQSEDRETSDRAHDENKKKAKIQKKPIKKKKEDDVGIERGNIE 983
Query: 138 ----KGRSKSPRETGGKRHESSSEKKERKGYSPTHREE---EYGKNHHNSSKKEKNKTEN 190
G+ SP++ G K+ ++K+ KG S EE + K + K E
Sbjct: 984 TTSEDGQVFSPKK-GQKKKSIEKKRKKSKGDSDISDEEAAQQSKKKRGPRTPPITTKEEL 1042
Query: 191 TRLGDNRKRLSERLEEKEDNEEGVYDYENTGRMTQKWIQSGHIATYYT------------ 238
+ + + + E ++KED + E+ T+ ++ H AT T
Sbjct: 1043 VEMCNGKNGILEDSQKKEDTAFSDWSDEDVPDRTEV-TEAEHTATATTPGSTPSPLSSLL 1101
Query: 239 -----IQDEAYDTTDSLLEENKIYERSRSSDGKSSSQVNRSRHENTSQVPLQESRTRKRR 293
+ T + L + S + + + T+ E RK
Sbjct: 1102 PPPPPVATATATTVPATLAATTAAAATSFSTSAITISTSATPTNTTNNTFANEDSHRKCH 1161
Query: 294 GSRVSQDRDSEGHSEDSERHSGSASRNHHGSAWEQSRDGS----RHPRSHDEDRASHGHS 349
+RV + ED++ H +Q R S R RSH R S
Sbjct: 1162 RTRVEKVETPHVTIEDAQ----------HRKPMDQKRSSSLGSNRSNRSHTSGRL-RSPS 1210
Query: 350 ADSSRQSGTRHAETSSRGQTASSHEQARSSPGERHGSGHQQS-ADSSRHSATGRGQASSA 408
DS+ +SG + S R + S + R +G ++S D + R +S
Sbjct: 1211 NDSAHRSGD---DQSGRKRVLHSGSRDREKTKSLEITGERKSRIDQLKRGEPSRSTSSDR 1267
Query: 409 VSDRGHRGSSGSQASDSEGHSENSDTQSVSGHGKAGLRQQSHQESTRGRSGERSGRSGSS 468
R H S SD + HS + S + L+++ E R R ER
Sbjct: 1268 QDSRSHSSRRSSPESDRQVHSRSGSFDS-----RDRLQERDRYEHDRERERERRDTRQRE 1322
Query: 469 LYQVSTHEQPDSAHGRTGTSTGGRQGSHHEQARDSSRHSASQEGQDTIRGHPGSSRGGRQ 528
+ + + P R R+ R + D++ R
Sbjct: 1323 WDRDADKDWP---RNRDRDRLRERERERERDKRRDLDRERERLISDSVERDRDRDRDRTF 1379
Query: 529 GSHHEQSVNR--SGHSGSHHSHTTSQGRSDASHGQSGSRSASRQTRNEEQSGDGTRHSGS 586
S +SV R + G H S R + + + E++ R
Sbjct: 1380 ESSQIESVKRCEAKLEGEHERDLESTSRDSLALDKERMDKDLGSVQGFEETNKSERTESL 1439
Query: 587 RHHEASSQADSSRHSQVGQGQSSGPRTSRNQGSSVSQDSDSQGHSEDSER 636
+ S+ D + G G+ P + ++ D++ + +D E+
Sbjct: 1440 EAGDDESKLDDAHSLGSGAGEGYEPISDDELDEILAGDAEKREDQQDEEK 1489
Score = 47.0 bits (110), Expect = 4e-04
Identities = 72/353 (20%), Positives = 126/353 (35%), Gaps = 51/353 (14%)
Query: 3648 SSAVRDSGHRGSSGSQASDSEGHSEDSDTQSVSAHGQAGPHQQSHQESTRGRSAGRS--- 3704
S ++R S S S +D T +VS+ QQ + ++ + + G
Sbjct: 209 SPSLRKSSKSPKRKSSPKSSSASKKDRKTSAVSSPLL---DQQRNSKTNQSKKKGPRTPS 265
Query: 3705 -----------GRSGSFLYQVSTHEQSESAHGRAGPSTGGRQGSRHEQARDSSRHSASQE 3753
G+ Y+V + ++ G+ GR R + RD R S S
Sbjct: 266 PPPPIPEDIALGKKYKEKYKVKDRIEEKTRDGK----DRGRDFERQREKRDKPR-STSPA 320
Query: 3754 GQD----TIRGHPGSRRGGRQGSYHEQSVDRSGHSGSHHSHT-TSQGRSDASHGQSGSRS 3808
GQ + R H S + G H S R + T T R AS S S S
Sbjct: 321 GQHHSPISSRHHSSSSQSGSSIQRHSPSPRRKRTPSPSYQRTLTPPLRRSASPYPSHSLS 380
Query: 3809 ASRETRNEEQSGDGSRHSGSRHHEASTQADSSRHSQSGQGESAGSRRSRRQGSSVSQDSD 3868
+ + ++ + R G HE ++Q+ RH RR+ + +D +
Sbjct: 381 SPQRKQSPPRHRSPMREKGRHDHERTSQSHDRRHE-------------RREDTRGKRDRE 427
Query: 3869 SEAYPEDSERRSESASRNHHGSSREQSRDGSRHPGSSHRDTASHVQSSPVQSDSSTAKEH 3928
++ E + +S+SR+H + RDG + ++ S DS +++
Sbjct: 428 KDSREEREYEQDQSSSRDHRDD--REPRDGRDRRDARDTRDRRELRDSRDMRDSREMRDY 485
Query: 3929 GHFSSLSQDSAYHSGIQSRGSPHSSSSYHYQS-EGTERQKGQSGLVWRHGSYG 3980
+ S+D R S + ++ Y+ EG + + + SYG
Sbjct: 486 SRDTKESRD--------PRDSRSTRDAHDYRDREGRDTHRKEDTYPEESRSYG 530
Score = 40.8 bits (94), Expect = 0.028
Identities = 36/129 (27%), Positives = 51/129 (39%), Gaps = 12/129 (9%)
Query: 3789 SHTTSQGRSDASHGQSGSRSASRETRNEEQSGDGSR----HSGSRHHEASTQAD-----S 3839
S + RS+ SH RS S ++ + R HSGSR E + +
Sbjct: 1189 SSSLGSNRSNRSHTSGRLRSPSNDSAHRSGDDQSGRKRVLHSGSRDREKTKSLEITGERK 1248
Query: 3840 SRHSQSGQGESAGSRRSRRQGSSVSQDSDSEAYPEDSERRSESASRNHHGSSREQSRDGS 3899
SR Q +GE + S S RQ S+ S +S+R+ S S + R Q RD
Sbjct: 1249 SRIDQLKRGEPSRSTSSDRQD---SRSHSSRRSSPESDRQVHSRSGSFDSRDRLQERDRY 1305
Query: 3900 RHPGSSHRD 3908
H R+
Sbjct: 1306 EHDRERERE 1314
>gi|7706635 cornulin [Homo sapiens]
Length = 495
Score = 103 bits (256), Expect = 5e-21
Identities = 116/476 (24%), Positives = 192/476 (40%), Gaps = 81/476 (17%)
Query: 1 MSTLLENIFAIINLFKQYSKKDKNTDTLSKKELKELLEKEFRQILKNPDDPDMVDVFMDH 60
M LL+NI II F++Y++ + N L++ ELK LLE+EF ++ P DP VD +
Sbjct: 1 MPQLLQNINGIIEAFRRYARTEGNCTALTRGELKRLLEQEFADVIVKPHDPATVDEVLRL 60
Query: 61 LDIDHNKKIDFTEFLLMVFKLAQAYYE--STRKENLPISGHKHRKHSHHDKHEDNKQEEN 118
LD DH ++F EFL++VFK+AQA ++ S E S HS + Q
Sbjct: 61 LDEDHTGTVEFKEFLVLVFKVAQACFKTLSESAEGACGSQESGSLHSGASQELGEGQRSG 120
Query: 119 KE-----NRKRPSSLERRNNRKGNKGRSKSPRETGGK--------RHESSSEKKERKGYS 165
E + R +++G++G+++ +T G+ ++ +E + ++ S
Sbjct: 121 TEVGRAGKGQHYEGSSHRQSQQGSRGQNRPGVQTQGQATGSAWVSSYDRQAESQSQERIS 180
Query: 166 PTHREEEYGKNHHNSSKKEKNKTENTRLGDNRKRLSERLEEKEDNEEGVYDYENTGRMTQ 225
P + + G+ E + + T + R+ + + E V TG TQ
Sbjct: 181 P--QIQLSGQTEQTQKAGEGKRNQTTEMRPERQPQTREQDRAHQTGETV-----TGSGTQ 233
Query: 226 KWIQSGHIATYYTIQDEAYDTTDSLLEENKIYERSRSSDGKSSSQVNRSRHENTSQVPLQ 285
Q+G AT QD ++ T G++S Q Q
Sbjct: 234 --TQAG--ATQTVEQDSSHQT------------------GRTSKQT-------------Q 258
Query: 286 ESRTRKRRGSRVSQDRDSEGHSEDSERHSGSASRNHHGSAWEQSRDGSRHPRSHDEDRAS 345
E+ + RG+ + +G S+ S+ +G G A Q+ ++ P E
Sbjct: 259 EATNDQNRGT----ETHGQGRSQTSQAVTG-------GHAQIQAGTHTQTPTQTVEQ--- 304
Query: 346 HGHSADSSRQSGTRHAET--SSRGQTASS--HEQARSSPGERHGSGHQQSADSSRHSATG 401
DSS Q+G+ +T S+ GQ + H Q RS + GH Q + H+ T
Sbjct: 305 -----DSSHQTGSTSTQTQESTNGQNRGTEIHGQGRSQTSQAVTGGHTQ-IQAGSHTETV 358
Query: 402 RGQASSAVSDRGHRGSSGSQASDSEGHSENSDTQSVSGHGKAGLRQQSHQESTRGR 457
S VS G R +Q G + +G G + Q+ + GR
Sbjct: 359 EQDRSQTVSHGGAREQGQTQTQPGSGQRWMQVSNPEAGETVPGGQAQTGASTESGR 414
Score = 77.4 bits (189), Expect = 3e-13
Identities = 92/403 (22%), Positives = 156/403 (38%), Gaps = 33/403 (8%)
Query: 555 SDASHGQSGSRS-------ASRQTRNEEQSGDGTRHSGS-RHHEASSQADSSRHSQVGQG 606
S+++ G GS+ AS++ ++SG +G +H+E SS S + S+ GQ
Sbjct: 90 SESAEGACGSQESGSLHSGASQELGEGQRSGTEVGRAGKGQHYEGSSHRQSQQGSR-GQN 148
Query: 607 QSSGPRTSRNQGSSVSQDSDSQGHSEDSERWSGSASRNHHGSAQEQSRDGSRHPRSH-HE 665
+ + GS+ D Q S+ ER S + +++ +G R+ +
Sbjct: 149 RPGVQTQGQATGSAWVSSYDRQAESQSQERISPQIQLSGQTEQTQKAGEGKRNQTTEMRP 208
Query: 666 DRAGHGHSADSSRKSGTRHTQNSSSGQAASSHEQARSSAGERHGSRHQLQSADSSRHSGT 725
+R D + ++G T + + QA ++ + S+ + + Q Q A + ++ GT
Sbjct: 209 ERQPQTREQDRAHQTGETVTGSGTQTQAGATQTVEQDSSHQTGRTSKQTQEATNDQNRGT 268
Query: 726 -GHGQASSAVRDSGHRGSSGSQATDSEGHSEDSDTQSVSGHGQAGHHQQSHQESARDRSG 784
HGQ R + +G A G + TQ+V SHQ +
Sbjct: 269 ETHGQG----RSQTSQAVTGGHAQIQAGTHTQTPTQTV-------EQDSSHQTGSTSTQT 317
Query: 785 ERSRRSGSFLYQVSTHKQSESSHGWTGPSTGVRQGSHHEQARDNSRHSASQDG---QDTI 841
+ S + ++ +S++S TG T ++ GSH E + + S G Q
Sbjct: 318 QESTNGQNRGTEIHGQGRSQTSQAVTGGHTQIQAGSHTETVEQDRSQTVSHGGAREQGQT 377
Query: 842 RGHPGSSRRGRQGSHHEQSVDRSGHSGSHHSHTTSQGRSDASRGQ------SGSRSASRT 895
+ PGS +R Q S+ E G + T S GR + S G T
Sbjct: 378 QTQPGSGQRWMQVSNPEAGETVPGGQAQTGASTES-GRQEWSSTHPRRCVTEGQGDRQPT 436
Query: 896 TRNEEQSRDGSRHSG-SRHHEASSHADISRHSQAGQGQSEGSR 937
EE D SR + R + + H +S QSE R
Sbjct: 437 VVGEEWVDDHSRETVILRLDQGNLHTSVSSAQGQDAAQSEEKR 479
Score = 73.6 bits (179), Expect = 4e-12
Identities = 106/419 (25%), Positives = 158/419 (37%), Gaps = 56/419 (13%)
Query: 2486 GHSGSHHSHTTSQGRSDASHGHSGSRSASRQTRNDEQSGDGSRHSGSRHHEASSRADSSG 2545
G GS S + G S G RS + R +G G + GS H + S+ S G
Sbjct: 95 GACGSQESGSLHSGASQELG--EGQRSGTEVGR----AGKGQHYEGSSHRQ--SQQGSRG 146
Query: 2546 HSQVGQGQSEGPRTSRNWGSSFSQDSDSQGHSEDSERWSGSASRNHHGSAQEQLRDGSRH 2605
++ G Q++G T W SS+ D Q S+ ER S + ++ +G R+
Sbjct: 147 QNRPGV-QTQGQATGSAWVSSY----DRQAESQSQERISPQIQLSGQTEQTQKAGEGKRN 201
Query: 2606 PRSH-QEDRAGHGHSADSSRQSGT----RHTQTSSGG----QAASSHEQARSSAGERHGS 2656
+ + +R D + Q+G TQT +G + SSH+ R+S + +
Sbjct: 202 QTTEMRPERQPQTREQDRAHQTGETVTGSGTQTQAGATQTVEQDSSHQTGRTSKQTQEAT 261
Query: 2657 HHQQSADSSRHSGIGHGQASSAVRDSGHRGYSGSQASDNEGHSEDSDTQSV---SAHGQA 2713
+ Q + G G Q S AV +G A G + TQ+V S+H Q
Sbjct: 262 NDQNRGTETH--GQGRSQTSQAV--------TGGHAQIQAGTHTQTPTQTVEQDSSH-QT 310
Query: 2714 GSHQQSHQESARGRSGETSGHSGSFLYQVSTHEQSESSHGWTGPSTRGRQGSRHEQAQDS 2773
GS QES G++ T H +S++S TG T+ + GS E +
Sbjct: 311 GSTSTQTQESTNGQNRGTEIHG---------QGRSQTSQAVTGGHTQIQAGSHTETVEQD 361
Query: 2774 SRHSASQDG---QDTIRGHPGSSRGGRQGYHHEHSVDSSGHSGSHHSHTTSQGRSDASRG 2830
+ S G Q + PGS + Q + E G + T S GR + S
Sbjct: 362 RSQTVSHGGAREQGQTQTQPGSGQRWMQVSNPEAGETVPGGQAQTGASTES-GRQEWSST 420
Query: 2831 Q------SGSRSASRTTRNEEQSGDGSRHSG-SRHHEASTHADISRHSQAVQGQSEGSR 2882
G T EE D SR + R + + H +S QSE R
Sbjct: 421 HPRRCVTEGQGDRQPTVVGEEWVDDHSRETVILRLDQGNLHTSVSSAQGQDAAQSEEKR 479
Score = 72.8 bits (177), Expect = 7e-12
Identities = 110/428 (25%), Positives = 165/428 (38%), Gaps = 64/428 (14%)
Query: 2805 SVDSSGHSGSHHSHTTSQGRSDASRGQSGSRSASRTTRNEEQSGDGSRHSGSRHHEASTH 2864
S + G GS S + G S G RS + R +G G + GS H ++
Sbjct: 90 SESAEGACGSQESGSLHSGASQELG--EGQRSGTEVGR----AGKGQHYEGSSHRQSQQG 143
Query: 2865 A-DISRHSQAVQGQSEGSR---RSRRQGSSVSQDSDS-----EGHSEDSERWSGSASRNH 2915
+ +R QGQ+ GS RQ S SQ+ S G +E +++ +G RN
Sbjct: 144 SRGQNRPGVQTQGQATGSAWVSSYDRQAESQSQERISPQIQLSGQTEQTQK-AGEGKRNQ 202
Query: 2916 HGSAQEQLRDGSRHPRSHQEDRAGHGHSADSSRQSGTRHTQTSSGG----QAASSHEQAR 2971
+ + R P++ ++DRA + ++ SGT QT +G + SSH+ R
Sbjct: 203 TTEMRPE-----RQPQTREQDRAHQ--TGETVTGSGT---QTQAGATQTVEQDSSHQTGR 252
Query: 2972 SSAGERHGSHHQQSADSSRHSGIGHGQASSAVRDSGHRGYSGSQASDNEGHSEDSDTQSV 3031
+S + ++ Q + G G Q S AV +G A G + TQ+V
Sbjct: 253 TSKQTQEATNDQNRGTETH--GQGRSQTSQAV--------TGGHAQIQAGTHTQTPTQTV 302
Query: 3032 ---SAHGQAGSHQQSHQESARGRSGETSGHSGSFLYQVSTHEQSESSHGWTGPSTRGRQG 3088
S+H Q GS QES G++ T H +S++S TG T+ + G
Sbjct: 303 EQDSSH-QTGSTSTQTQESTNGQNRGTEIHGQG---------RSQTSQAVTGGHTQIQAG 352
Query: 3089 SRHEQAQDSSRHSASQYG---QDTIRGHPGSSRGGRQGYHHEHSVDSSGHSGSHHSHTTS 3145
S E + + S G Q + PGS + Q + E G + T S
Sbjct: 353 SHTETVEQDRSQTVSHGGAREQGQTQTQPGSGQRWMQVSNPEAGETVPGGQAQTGASTES 412
Query: 3146 QGRSDASRGQ------SGSRSASRTTRNEEQSGDSSRHSV-SRHHEASTHADISRHSQAV 3198
GR + S G T EE D SR +V R + + H +S
Sbjct: 413 -GRQEWSSTHPRRCVTEGQGDRQPTVVGEEWVDDHSRETVILRLDQGNLHTSVSSAQGQD 471
Query: 3199 QGQSEGSR 3206
QSE R
Sbjct: 472 AAQSEEKR 479
Score = 72.0 bits (175), Expect = 1e-11
Identities = 108/417 (25%), Positives = 161/417 (38%), Gaps = 49/417 (11%)
Query: 999 ADSSRQSGTPHAETSS--GGQAASSHEQARSSPGERH-GSRHQQSADSSRHSGIPRRQAS 1055
A S++SG+ H+ S G S E R+ G+ + GS H+QS SR P Q
Sbjct: 96 ACGSQESGSLHSGASQELGEGQRSGTEVGRAGKGQHYEGSSHRQSQQGSRGQNRPGVQTQ 155
Query: 1056 SAVRDSGHWGSSGSQASDSEGHSEESDTQSVSGHGQDGPHQQSHQESARDWSGGRSGRSG 1115
S W SS + ++S+ S+E + + GQ Q++ + + R R
Sbjct: 156 GQATGSA-WVSSYDRQAESQ--SQERISPQIQLSGQTEQTQKAGEGKRNQTTEMRPERQP 212
Query: 1116 SFIYQVSTHEQSESAHGR-TRTSTGRRQGSHHEQARDSSRHSASQEGQDTIRAHPGSRRG 1174
Q H+ E+ G T+T G Q + + + R S Q + T + G+
Sbjct: 213 QTREQDRAHQTGETVTGSGTQTQAGATQTVEQDSSHQTGRTS-KQTQEATNDQNRGTETH 271
Query: 1175 GRQGSHHEQSVDRSGHS----GSHHSHTTSQGRSDASHGQSGSRSASRQTRKDKQSGDGS 1230
G+ S Q+V GH+ G+H T D+SH Q+GS S Q + Q+
Sbjct: 272 GQGRSQTSQAVT-GGHAQIQAGTHTQTPTQTVEQDSSH-QTGSTSTQTQESTNGQNRGTE 329
Query: 1231 RHSGSRHHEAASWADSSRHSQVGQEQSSGSRTSR-HQGSSVSQDSDSERHSDDSERLSGS 1289
H R S A + H+Q+ +GS T Q S + R ++ GS
Sbjct: 330 IHGQGRSQ--TSQAVTGGHTQI----QAGSHTETVEQDRSQTVSHGGAREQGQTQTQPGS 383
Query: 1290 ASRNHHGSSREQSRDGSRHPGFHQEDRASHGHSADSSRQ--SGTHHTESSSHGQA----- 1342
R S+ E G PG +A G S +S RQ S TH + GQ
Sbjct: 384 GQRWMQVSNPEA---GETVPG----GQAQTGASTESGRQEWSSTHPRRCVTEGQGDRQPT 436
Query: 1343 ------VSSHEQ----ARSSPGERHGS----RHQQSADSSRHSGIGHRQASSAVRDS 1385
V H + R G H S + Q +A S GI R+ S +R +
Sbjct: 437 VVGEEWVDDHSRETVILRLDQGNLHTSVSSAQGQDAAQSEEKRGITARELYSYLRST 493
Score = 67.0 bits (162), Expect = 4e-10
Identities = 98/394 (24%), Positives = 155/394 (39%), Gaps = 58/394 (14%)
Query: 2299 SRQSGTHH--AENSSGGQAASSHEQARSSAGERH-GSHHQQSADSSRHSGIGHGQASSAV 2355
S++SG+ H A G S E R+ G+ + GS H+QS SR GQ V
Sbjct: 99 SQESGSLHSGASQELGEGQRSGTEVGRAGKGQHYEGSSHRQSQQGSR------GQNRPGV 152
Query: 2356 RDSGHRGSSGSQAS---DSEGHSEDSDTQSVSAHGQAGPHQQSHQESTRGRSAGRSGRSG 2412
+ G S +S +E S++ + + GQ Q++ + + R R
Sbjct: 153 QTQGQATGSAWVSSYDRQAESQSQERISPQIQLSGQTEQTQKAGEGKRNQTTEMRPERQP 212
Query: 2413 SFLYQVSTHEQSESAHGRTGTSTGGRQGSHHKQARDSSRHS--TSQEGQDTIHG-HPGSS 2469
Q H+ E+ TG+ T + G+ +DSS + TS++ Q+ + + G+
Sbjct: 213 QTREQDRAHQTGETV---TGSGTQTQAGATQTVEQDSSHQTGRTSKQTQEATNDQNRGTE 269
Query: 2470 SGGRQGSHYEQLVDRSGHS----GSHHSHTTSQGRSDASHGHSGSRSASRQTRNDEQSGD 2525
+ G+ S Q V GH+ G+H T D+SH +GS S Q + Q+
Sbjct: 270 THGQGRSQTSQAVT-GGHAQIQAGTHTQTPTQTVEQDSSH-QTGSTSTQTQESTNGQNRG 327
Query: 2526 GSRHSGSRHHEASSRADSSGHSQVGQG-----------QSEGPRTSRNWGSSFSQDSDSQ 2574
H R +S+A + GH+Q+ G Q+ +R G + +Q Q
Sbjct: 328 TEIHGQGRSQ--TSQAVTGGHTQIQAGSHTETVEQDRSQTVSHGGAREQGQTQTQPGSGQ 385
Query: 2575 -----GHSEDSERWSGSASRNHHGSAQEQLRDGSRHPR----SHQEDR----AGHGHSAD 2621
+ E E G ++ + + S HPR Q DR G D
Sbjct: 386 RWMQVSNPEAGETVPGGQAQTGASTESGRQEWSSTHPRRCVTEGQGDRQPTVVGEEWVDD 445
Query: 2622 SSRQS-------GTRHTQTSSG-GQAASSHEQAR 2647
SR++ G HT SS GQ A+ E+ R
Sbjct: 446 HSRETVILRLDQGNLHTSVSSAQGQDAAQSEEKR 479
Score = 65.5 bits (158), Expect = 1e-09
Identities = 93/389 (23%), Positives = 149/389 (38%), Gaps = 48/389 (12%)
Query: 3271 SRQSGTRHAETSS--GGQAASSHEQARSSPGERH-GSRHQQSADSSRHSGIPRGQASSAV 3327
S++SG+ H+ S G S E R+ G+ + GS H+QS SR P Q
Sbjct: 99 SQESGSLHSGASQELGEGQRSGTEVGRAGKGQHYEGSSHRQSQQGSRGQNRPGVQTQGQA 158
Query: 3328 RDSRHWGSSGSQASDSEGHSEESDTQSVSGHGQAGPHQQSHQESARDRSGGRSGRSGSFL 3387
S W SS + ++S+ S+E + + GQ Q++ + + R R
Sbjct: 159 TGSA-WVSSYDRQAESQ--SQERISPQIQLSGQTEQTQKAGEGKRNQTTEMRPERQPQTR 215
Query: 3388 YQVSTHEQSESAHGR-TRTSTGRRQGSHHEQARDSSRHSASQEGQDTIRGHPGSSRRGRQ 3446
Q H+ E+ G T+T G Q + + + R S Q + T + G+ G+
Sbjct: 216 EQDRAHQTGETVTGSGTQTQAGATQTVEQDSSHQTGRTS-KQTQEATNDQNRGTETHGQG 274
Query: 3447 GSHYEQSVDRSGHS---GSHHSHTTSQGRSDASRGQSGSRSASRQTRNDEQSGDGSRHSW 3503
S Q+V GH+ H+ T +Q S Q+GS S Q + Q+ H
Sbjct: 275 RSQTSQAVT-GGHAQIQAGTHTQTPTQTVEQDSSHQTGSTSTQTQESTNGQNRGTEIHGQ 333
Query: 3504 SHHHEASTQADSSRHSQSGQG-----------QSAGPRTSRNQGSSVSQDSDSQGHSEDS 3552
++QA + H+Q G Q+ +R QG + +Q Q + S
Sbjct: 334 GRSQ--TSQAVTGGHTQIQAGSHTETVEQDRSQTVSHGGAREQGQTQTQPGSGQRWMQVS 391
Query: 3553 ERWSGS---ASRNHRGSAQEQSR---------------DGSRHPTSHHEDRAGHGHSAES 3594
+G + G++ E R G R PT E+ HS E+
Sbjct: 392 NPEAGETVPGGQAQTGASTESGRQEWSSTHPRRCVTEGQGDRQPTVVGEEWV-DDHSRET 450
Query: 3595 ----SRQSGTHHAENSSGGQAASSHEQAR 3619
Q H + +S+ GQ A+ E+ R
Sbjct: 451 VILRLDQGNLHTSVSSAQGQDAAQSEEKR 479
Score = 64.7 bits (156), Expect = 2e-09
Identities = 91/388 (23%), Positives = 148/388 (38%), Gaps = 46/388 (11%)
Query: 1650 SRQSGTRHAETSS--GGQAASSQEQARSSPGERH-GSRHQQSADSSTDSGTGRRQDSSVV 1706
S++SG+ H+ S G S E R+ G+ + GS H+QS S R
Sbjct: 99 SQESGSLHSGASQELGEGQRSGTEVGRAGKGQHYEGSSHRQSQQGSRGQN---RPGVQTQ 155
Query: 1707 GDSGNRGSSGSQASDSEGHSEESDTQSVSAHGQAGPHQQSHQESTRGQSGE-RSGRSGSF 1765
G + S +E S+E + + GQ Q++ E R Q+ E R R
Sbjct: 156 GQATGSAWVSSYDRQAESQSQERISPQIQLSGQTEQTQKAG-EGKRNQTTEMRPERQPQT 214
Query: 1766 LYQVSTHEQSESAHGRTGPSTGGRQRSRHEQARDSSRHSASQEGQDTIRGHPGSSRGGRQ 1825
Q H+ E+ G + G ++ + + + ++ Q + T + G+ G+
Sbjct: 215 REQDRAHQTGETVTGSGTQTQAGATQTVEQDSSHQTGRTSKQTQEATNDQNRGTETHGQG 274
Query: 1826 GSHYEQSVDSSGHS---GSHHSHTTSQERSDVSRGQSGSRSVSRQTRNEKQSGDGSRHSG 1882
S Q+V + GH+ H+ T +Q S Q+GS S Q Q+ H
Sbjct: 275 RSQTSQAV-TGGHAQIQAGTHTQTPTQTVEQDSSHQTGSTSTQTQESTNGQNRGTEIHGQ 333
Query: 1883 SRHHEASSRADSSRHSQVGQG-----------QSSGPRTSRNQGSSVSQDSDSQGHSEDS 1931
R +S+A + H+Q+ G Q+ +R QG + +Q Q + S
Sbjct: 334 GRSQ--TSQAVTGGHTQIQAGSHTETVEQDRSQTVSHGGAREQGQTQTQPGSGQRWMQVS 391
Query: 1932 ERWSGS---ASRNHLGSAWEQSRD--GSRHP--------GSHHEDRAGHGHSADSSRQS- 1977
+G + G++ E R S HP G G D SR++
Sbjct: 392 NPEAGETVPGGQAQTGASTESGRQEWSSTHPRRCVTEGQGDRQPTVVGEEWVDDHSRETV 451
Query: 1978 ------GTRHTE-SSSRGQAASSHEQAR 1998
G HT SS++GQ A+ E+ R
Sbjct: 452 ILRLDQGNLHTSVSSAQGQDAAQSEEKR 479
Score = 64.3 bits (155), Expect = 2e-09
Identities = 88/363 (24%), Positives = 146/363 (40%), Gaps = 49/363 (13%)
Query: 1204 SDASHGQSGSR-SASRQTRKDKQSGDGSRHSGS--------RHHEAASWADSSRHSQVGQ 1254
S+++ G GS+ S S + ++ G+G R SG+ +H+E +S S + S+ GQ
Sbjct: 90 SESAEGACGSQESGSLHSGASQELGEGQR-SGTEVGRAGKGQHYEGSSHRQSQQGSR-GQ 147
Query: 1255 EQSSGSRTSRHQGSSVSQDSDSERHSDDSERLSGSASRNHHGSSREQSRDGSRHPGFH-Q 1313
+ + GS+ D + S ER+S + +++ +G R+ +
Sbjct: 148 NRPGVQTQGQATGSAWVSSYDRQAESQSQERISPQIQLSGQTEQTQKAGEGKRNQTTEMR 207
Query: 1314 EDRASHGHSADSSRQSGTHHTESSSHGQAVSSHEQARSSPGERHGSRHQQSADSSRHSGI 1373
+R D + Q+G T S + QA G+ DSS +G
Sbjct: 208 PERQPQTREQDRAHQTGETVTGSGTQTQA---------------GATQTVEQDSSHQTGR 252
Query: 1374 GHRQASSAVRDSGHRGSSGSQVTNSEGHSEDSDTQSVS---AHGQAGPHQQSHKESARGQ 1430
+Q A D +RG+ T+ +G S+ S Q+V+ A QAG H Q+ ++
Sbjct: 253 TSKQTQEATNDQ-NRGTE----THGQGRSQTS--QAVTGGHAQIQAGTHTQTPTQTVEQD 305
Query: 1431 SGESSGRSRSFLYQVSSHEQSEST--HGQTAPSTGGRQGSRHEQAR-NSSRHSASQDGQD 1487
S +G S S Q S++ Q+ T HGQ T H Q + S + QD
Sbjct: 306 SSHQTG-STSTQTQESTNGQNRGTEIHGQGRSQTSQAVTGGHTQIQAGSHTETVEQDRSQ 364
Query: 1488 TIRGHPGSSRGGRQGSYHEQSVDRSGHSGYHHSHTTPQGRSDASHGQSGPRSASRQTRNE 1547
T+ S GG + Q+ SG S+ P+ GQ+ +++ R E
Sbjct: 365 TV------SHGGAREQGQTQTQPGSGQRWMQVSN--PEAGETVPGGQAQTGASTESGRQE 416
Query: 1548 EQS 1550
S
Sbjct: 417 WSS 419
Score = 64.3 bits (155), Expect = 2e-09
Identities = 97/397 (24%), Positives = 151/397 (38%), Gaps = 58/397 (14%)
Query: 350 ADSSRQSGTRHAETSSR---GQTASSHEQARSSPGERH-GSGHQQSADSSRHS------A 399
A S++SG+ H+ S GQ + + E R+ G+ + GS H+QS SR
Sbjct: 96 ACGSQESGSLHSGASQELGEGQRSGT-EVGRAGKGQHYEGSSHRQSQQGSRGQNRPGVQT 154
Query: 400 TGRGQASSAVSDRGHRGSSGSQASDSEGHSENSDTQSVSGHGKAGLRQQSHQESTRG--- 456
G+ S+ VS + S SQ S + T+ G+ Q + R
Sbjct: 155 QGQATGSAWVSSYDRQAESQSQERISPQIQLSGQTEQTQKAGEGKRNQTTEMRPERQPQT 214
Query: 457 RSGERSGRSGSSLYQVSTHEQPDSAHGRTGTSTGGRQGSHHEQARDSSRHSASQEGQDTI 516
R +R+ ++G ++ T Q G + Q S H+ R S + + Q+
Sbjct: 215 REQDRAHQTGETVTGSGTQTQ-------AGATQTVEQDSSHQTGRTSKQTQEATNDQN-- 265
Query: 517 RGHPGSSRGGRQGSHHEQSVNRSGHSGSHHSHTTSQGRSDASHGQSGSRSASRQTRNEEQ 576
RG +G Q S + +G+H T D+SH Q+GS S Q Q
Sbjct: 266 RGTETHGQGRSQTSQAVTGGHAQIQAGTHTQTPTQTVEQDSSH-QTGSTSTQTQESTNGQ 324
Query: 577 SGDGTRHSGSRHHEASSQADSSRHSQVGQG-----------QSSGPRTSRNQGSSVSQDS 625
+ H R +SQA + H+Q+ G Q+ +R QG + +Q
Sbjct: 325 NRGTEIHGQGRSQ--TSQAVTGGHTQIQAGSHTETVEQDRSQTVSHGGAREQGQTQTQPG 382
Query: 626 DSQGHSEDSERWSGS---ASRNHHGSAQEQSRD--GSRHPR----SHHEDR----AGHGH 672
Q + S +G + G++ E R S HPR DR G
Sbjct: 383 SGQRWMQVSNPEAGETVPGGQAQTGASTESGRQEWSSTHPRRCVTEGQGDRQPTVVGEEW 442
Query: 673 SADSSRKS-------GTRHTQ-NSSSGQAASSHEQAR 701
D SR++ G HT +S+ GQ A+ E+ R
Sbjct: 443 VDDHSRETVILRLDQGNLHTSVSSAQGQDAAQSEEKR 479
Score = 64.3 bits (155), Expect = 2e-09
Identities = 88/361 (24%), Positives = 140/361 (38%), Gaps = 62/361 (17%)
Query: 3595 SRQSGTHH--AENSSGGQAASSHEQARSSAGERH-GSHHQQSADSSRHSGIGHGQASSAV 3651
S++SG+ H A G S E R+ G+ + GS H+QS SR GQ V
Sbjct: 99 SQESGSLHSGASQELGEGQRSGTEVGRAGKGQHYEGSSHRQSQQGSR------GQNRPGV 152
Query: 3652 RDSGHRGSSGSQAS---DSEGHSEDSDTQSVSAHGQAGPHQQSHQESTRGRSAGRSGRSG 3708
+ G S +S +E S++ + + GQ Q++ + + R R
Sbjct: 153 QTQGQATGSAWVSSYDRQAESQSQERISPQIQLSGQTEQTQKAGEGKRNQTTEMRPERQP 212
Query: 3709 SFLYQVSTHEQSESAHG-----RAGPSTGGRQGSRHEQARDSSRHSASQEGQDTIRGHPG 3763
Q H+ E+ G +AG + Q S H+ R S + + Q+ G
Sbjct: 213 QTREQDRAHQTGETVTGSGTQTQAGATQTVEQDSSHQTGRTSKQTQEATNDQNR-----G 267
Query: 3764 SRRGGRQGSYHEQSVDRSGHS----GSHHSHTTSQGRSDASHGQSGSRSASRETRNEEQS 3819
+ G+ S Q+V GH+ G+H T D+SH Q+GS T + Q
Sbjct: 268 TETHGQGRSQTSQAVT-GGHAQIQAGTHTQTPTQTVEQDSSH-QTGS------TSTQTQE 319
Query: 3820 GDGSRHSGSRHHEASTQADSSRHSQSGQGESAGSRRSRRQGSSVSQDSDSEAYPEDSERR 3879
++ G+ H GQG S S+ + + S +E +D R
Sbjct: 320 STNGQNRGTEIH--------------GQGRSQTSQAVTGGHTQIQAGSHTETVEQD---R 362
Query: 3880 SESASRNHHGSSREQSRDGSRHPGSSHR-------DTASHVQSSPVQSDSSTAKEHGHFS 3932
S++ S HG +REQ + ++ PGS R + V Q+ +ST +S
Sbjct: 363 SQTVS---HGGAREQGQTQTQ-PGSGQRWMQVSNPEAGETVPGGQAQTGASTESGRQEWS 418
Query: 3933 S 3933
S
Sbjct: 419 S 419
Score = 63.5 bits (153), Expect = 4e-09
Identities = 86/436 (19%), Positives = 158/436 (36%), Gaps = 54/436 (12%)
Query: 1775 SESAHGRTGPSTGGRQRSRHEQARDSSRHSASQEGQDTIRGHPGSSRGGRQGSHYEQSVD 1834
SESA G G G S Q + S ++ G R G+ G HYE S
Sbjct: 90 SESAEGACGSQESGSLHSGASQELGEGQRSGTEVG-----------RAGK-GQHYEGSSH 137
Query: 1835 SSGHSGSHHSHTTSQERSDVSRGQSGSRSVSRQTRNEKQSGDGSRHSGSRHHEASSRADS 1894
GS + + + G + S RQ ++ Q + S E + +A
Sbjct: 138 RQSQQGSRGQNRPGVQTQGQATGSAWVSSYDRQAESQSQERISPQIQLSGQTEQTQKAGE 197
Query: 1895 SRHSQVGQGQSSGPRTSRNQGSSVSQDSDSQGHSEDSERWSGSASRNHLGSAWEQSRDGS 1954
+ +Q + + +R Q + + E +GS ++ G+ +D S
Sbjct: 198 GKRNQTTEMRPERQPQTREQDRA----------HQTGETVTGSGTQTQAGATQTVEQDSS 247
Query: 1955 RHPGSHHEDRAGHGHSADSSRQSGTRHTESSSRGQAASSHEQARSSAGERHGSHHQLQSA 2014
G + + R TE+ +G++ +S A + G+H Q +
Sbjct: 248 HQTGRTSKQ-------TQEATNDQNRGTETHGQGRSQTSQAVTGGHAQIQAGTHTQTPTQ 300
Query: 2015 DSSRHSGIGHGQASSAVRDSGHRGYSGSQASDSEGHSEDSDTQSVS---AQGKAGPHQQS 2071
+ S G S+ ++S + ++ ++ G +Q+V+ Q +AG H ++
Sbjct: 301 TVEQDSSHQTGSTSTQTQESTN---GQNRGTEIHGQGRSQTSQAVTGGHTQIQAGSHTET 357
Query: 2072 HKES-----------ARGQSGESSGRSGSFLYQVSTHEQSESTHGQSAPSTGGRQGSHYD 2120
++ +GQ+ G SG QVS E E+ G A + + +
Sbjct: 358 VEQDRSQTVSHGGAREQGQTQTQPG-SGQRWMQVSNPEAGETVPGGQAQTGASTESGRQE 416
Query: 2121 QAQDSSRHSASQEGQDTIRGHPGPSRGGRQ--GSHQEQSVDRSGHSGSHHSHTTSQGRSD 2178
+ R + EGQ G P+ G + H ++V G+ H+ +S D
Sbjct: 417 WSSTHPRRCVT-EGQ----GDRQPTVVGEEWVDDHSRETVILRLDQGNLHTSVSSAQGQD 471
Query: 2179 ASRGQSGSRSASRKTY 2194
A++ + +R+ Y
Sbjct: 472 AAQSEEKRGITARELY 487
Score = 62.4 bits (150), Expect = 9e-09
Identities = 88/357 (24%), Positives = 141/357 (39%), Gaps = 51/357 (14%)
Query: 2177 SDASRGQSGSR-SASRKTYDKEQSGDGSRHSGSH--------HHEASSWADSSRHSLVGQ 2227
S+++ G GS+ S S + ++ G+G R SG+ H+E SS S + S GQ
Sbjct: 90 SESAEGACGSQESGSLHSGASQELGEGQR-SGTEVGRAGKGQHYEGSSHRQSQQGSR-GQ 147
Query: 2228 GQSSGPRTSRPRGSSVSQDSDSEGHSEDSERRSGSASRNHHGSAQEQSRDGSRH------ 2281
+ + GS+ D + S+ ER S + +++ +G R+
Sbjct: 148 NRPGVQTQGQATGSAWVSSYDRQAESQSQERISPQIQLSGQTEQTQKAGEGKRNQTTEMR 207
Query: 2282 ----PRSHHEDRAGHGHSAESSRQSGTH-HAENSSGGQAASSHEQARSSAGERHGSHHQQ 2336
P++ +DRA + E+ SGT A + + SSH+ R+S + ++ Q
Sbjct: 208 PERQPQTREQDRA--HQTGETVTGSGTQTQAGATQTVEQDSSHQTGRTSKQTQEATNDQN 265
Query: 2337 SADSSRHSGIGHGQASSAVRDSGHRGSSGSQASDSEGHSEDSDTQSV---SAHGQAGPHQ 2393
+ G G Q S AV +G A G + TQ+V S+H Q G
Sbjct: 266 RGTETH--GQGRSQTSQAV--------TGGHAQIQAGTHTQTPTQTVEQDSSH-QTGSTS 314
Query: 2394 QSHQESTRGRSAGRSGRSGSFLYQVSTHEQSESAHGRTGTSTGGRQGSHHKQARDSSRHS 2453
QEST G++ G ++ +S+++ TG T + GSH + +
Sbjct: 315 TQTQESTNGQNRGT---------EIHGQGRSQTSQAVTGGHTQIQAGSHTETVEQDRSQT 365
Query: 2454 TSQEG---QDTIHGHPGSSSGGRQGSHYEQLVDRSGHSGSHHSHTTSQGRSDASHGH 2507
S G Q PGS Q S+ E G + T S GR + S H
Sbjct: 366 VSHGGAREQGQTQTQPGSGQRWMQVSNPEAGETVPGGQAQTGASTES-GRQEWSSTH 421
Score = 61.6 bits (148), Expect = 2e-08
Identities = 94/459 (20%), Positives = 167/459 (36%), Gaps = 70/459 (15%)
Query: 3473 SDASRGQSGSR-SASRQTRNDEQSGDGSRHSWS-------HHHEASTQADSSRHSQSGQG 3524
S+++ G GS+ S S + ++ G+G R H+E S+ S + S+ GQ
Sbjct: 90 SESAEGACGSQESGSLHSGASQELGEGQRSGTEVGRAGKGQHYEGSSHRQSQQGSR-GQN 148
Query: 3525 QSAGPRTSRNQGSSVSQDSDSQGHSEDSERWSGSASRNHRGSAQEQSRDGSRHPTSHHED 3584
+ + GS+ D Q S+ ER S + + +++ +G R+ T+
Sbjct: 149 RPGVQTQGQATGSAWVSSYDRQAESQSQERISPQIQLSGQTEQTQKAGEGKRNQTTEMRP 208
Query: 3585 RAGHGHSAESSRQSGTHHAENSSGGQAASSHEQARSSAGERHGSHHQQSADSSRHSGIGH 3644
+ E R T SG Q + G+ DSS +G
Sbjct: 209 ER-QPQTREQDRAHQTGETVTGSGTQTQA-------------GATQTVEQDSSHQTGRTS 254
Query: 3645 GQASSAVRDSGHRGSSGSQASDSEGHSEDSDTQSVS---AHGQAGPHQQSHQESTRGRSA 3701
Q A D ++ +++ G +Q+V+ A QAG H Q+ ++ S+
Sbjct: 255 KQTQEATNDQ-------NRGTETHGQGRSQTSQAVTGGHAQIQAGTHTQTPTQTVEQDSS 307
Query: 3702 GRSGRSGSFLYQVSTHEQSESAHGRAGPSTGGRQGSRHEQARDSSRHSASQEGQDTIRGH 3761
++G + + + ES +G+ R H Q R SQ Q GH
Sbjct: 308 HQTGSTST--------QTQESTNGQ------NRGTEIHGQGR-------SQTSQAVTGGH 346
Query: 3762 PGSRRGGRQGSYHEQSVDRSGHSGSHHSHTTSQGRSDASHGQSGSRSASRETRNEEQSGD 3821
+ G H ++V++ H QG++ G SG R ++
Sbjct: 347 TQIQAGS-----HTETVEQDRSQTVSHGGAREQGQTQTQPG-SGQRWMQVSNPEAGETVP 400
Query: 3822 GSRHSGSRHHEASTQADSSRHSQSGQGESAGSRRSRRQGSSVSQDSDSEA----YPEDSE 3877
G + E+ Q SS H + E G R+ G D E + +
Sbjct: 401 GGQAQTGASTESGRQEWSSTHPRRCVTEGQGDRQPTVVGEEWVDDHSRETVILRLDQGNL 460
Query: 3878 RRSESASRNHHGSSREQSRDGSRHPGSSHRDTASHVQSS 3916
S S+++ + E+ R G + R+ S+++S+
Sbjct: 461 HTSVSSAQGQDAAQSEEKR------GITARELYSYLRST 493
Score = 58.2 bits (139), Expect = 2e-07
Identities = 82/354 (23%), Positives = 142/354 (40%), Gaps = 47/354 (13%)
Query: 1528 SDASHGQSGPR-SASRQTRNEEQSGDGSRHSGS--------RHHEPSTRAGSSRHSQVGQ 1578
S+++ G G + S S + ++ G+G R SG+ +H+E S+ S + S+ GQ
Sbjct: 90 SESAEGACGSQESGSLHSGASQELGEGQR-SGTEVGRAGKGQHYEGSSHRQSQQGSR-GQ 147
Query: 1579 GESAGSKTSRRQGSSVSQDRDSEGHSEDSERRSESASRNHYGSAREQSRHGSRNPRSH-Q 1637
+ GS+ D + S+ ER S + +++ G RN + +
Sbjct: 148 NRPGVQTQGQATGSAWVSSYDRQAESQSQERISPQIQLSGQTEQTQKAGEGKRNQTTEMR 207
Query: 1638 EDRASHGHSAESSRQSGTRHAETSSGGQAASSQEQARSSPGERHGSRHQQSADSSTDSGT 1697
+R + + Q+G ET +G + +Q QA G+ DSS +G
Sbjct: 208 PERQPQTREQDRAHQTG----ETVTG---SGTQTQA--------GATQTVEQDSSHQTGR 252
Query: 1698 GRRQDSSVVGDSGNRGSSGSQASDSEGHSEESDTQSVS---AHGQAGPHQQSHQESTRGQ 1754
+Q D NRG +++ G +Q+V+ A QAG H Q+ ++
Sbjct: 253 TSKQTQEATNDQ-NRG------TETHGQGRSQTSQAVTGGHAQIQAGTHTQTPTQTVEQD 305
Query: 1755 SGERSGRSGSFLYQVSTHEQSESA--HGRTGPSTGGRQRSRHEQARDSSR-HSASQEGQD 1811
S ++G S S Q ST+ Q+ HG+ T H Q + S + Q+
Sbjct: 306 SSHQTG-STSTQTQESTNGQNRGTEIHGQGRSQTSQAVTGGHTQIQAGSHTETVEQDRSQ 364
Query: 1812 TIRGHPGSSRGGRQGSHYEQSVDSSGHSGSHHSHTTSQERSDVSRGQSGSRSVS 1865
T+ S GG + Q+ SG S+ + E + Q+G+ + S
Sbjct: 365 TV------SHGGAREQGQTQTQPGSGQRWMQVSNPEAGETVPGGQAQTGASTES 412
Score = 57.8 bits (138), Expect = 2e-07
Identities = 112/457 (24%), Positives = 164/457 (35%), Gaps = 77/457 (16%)
Query: 1323 ADSSRQSGTHHTESSSH---GQAVSSHEQARSSPGERH-GSRHQQSADSSRHSGIGHRQA 1378
A S++SG+ H+ +S GQ S E R+ G+ + GS H+QS SR Q
Sbjct: 96 ACGSQESGSLHSGASQELGEGQR-SGTEVGRAGKGQHYEGSSHRQSQQGSRGQNRPGVQT 154
Query: 1379 SSAVRDSGHRGSSGSQVTNSEGHSEDSDTQSVSAHGQAGPHQQSHKESARGQSGESSG-R 1437
S S Q +E S++ + + GQ Q++ E R Q+ E R
Sbjct: 155 QGQATGSAWVSSYDRQ---AESQSQERISPQIQLSGQTEQTQKAG-EGKRNQTTEMRPER 210
Query: 1438 SRSFLYQVSSHEQSESTHGQTAPSTGG-----RQGSRHEQARNSSRHSASQDGQDTIRGH 1492
Q +H+ E+ G + G Q S H+ R S + + + Q+ RG
Sbjct: 211 QPQTREQDRAHQTGETVTGSGTQTQAGATQTVEQDSSHQTGRTSKQTQEATNDQN--RGT 268
Query: 1493 PGSSRGGRQGSYHEQSVDRSGHSGYHHSHTTPQGRSDASHGQSGPRSASRQTRNEEQSGD 1552
+G Q S +G H T D+SH Q+G S Q Q+
Sbjct: 269 ETHGQGRSQTSQAVTGGHAQIQAGTHTQTPTQTVEQDSSH-QTGSTSTQTQESTNGQNRG 327
Query: 1553 GSRHSGSRHHEPSTRAGSSRHSQVGQGESAGSKTSRRQGSSVSQDRDSEGHSEDSERRSE 1612
H R +++A + H+Q+ AGS T +V QD RS+
Sbjct: 328 TEIHGQGR--SQTSQAVTGGHTQI----QAGSHT-----ETVEQD------------RSQ 364
Query: 1613 SASRNHYGSAREQSRHGSRNPRSHQEDRASHGHSAESSRQSGTRHAETSSGGQA--ASSQ 1670
+ S +G AREQ + + G + S ET GGQA +S
Sbjct: 365 TVS---HGGAREQG-----------QTQTQPGSGQRWMQVSNPEAGETVPGGQAQTGAST 410
Query: 1671 EQARSSPGERHGSRHQQSADSSTDSGTGRRQDSSVVGDSGNRGSSGSQASDSEGHSEESD 1730
E R H R G G RQ +VVG+ + HS E+
Sbjct: 411 ESGRQEWSSTHPRR-------CVTEGQGDRQ-PTVVGEEW-----------VDDHSRETV 451
Query: 1731 TQSVSAHGQAGPHQQSHQESTRGQSGERSGRSGSFLY 1767
+ G S Q QS E+ G + LY
Sbjct: 452 ILRLD-QGNLHTSVSSAQGQDAAQSEEKRGITARELY 487
Score = 56.2 bits (134), Expect = 6e-07
Identities = 113/472 (23%), Positives = 172/472 (36%), Gaps = 110/472 (23%)
Query: 2056 TQSVSAQGKAGP------HQQSHKESARGQ-SGESSGRSGSFL-YQVSTHEQSES-THGQ 2106
T S SA+G G H + +E GQ SG GR+G Y+ S+H QS+ + GQ
Sbjct: 88 TLSESAEGACGSQESGSLHSGASQELGEGQRSGTEVGRAGKGQHYEGSSHRQSQQGSRGQ 147
Query: 2107 SAP-------STGGRQGSHYD-QAQDSSRHSASQEGQDTIRGHPGPSRGGRQGSHQEQSV 2158
+ P +TG S YD QA+ S+ S + Q S Q +
Sbjct: 148 NRPGVQTQGQATGSAWVSSYDRQAESQSQERISPQ---------------IQLSGQTEQT 192
Query: 2159 DRSGHSGSHHSHTTSQGRSDASRGQSGSRSASRKTYDKEQSGDGSRHSGSHHHEASSWAD 2218
++G + R Q+ R+ +EQ D + +G
Sbjct: 193 QKAG---------------EGKRNQTTEMRPERQPQTREQ--DRAHQTG----------- 224
Query: 2219 SSRHSLVGQGQSSGPRTSRPRGSSVSQDSDSEGHSEDSERRSGSASRNHHGSAQEQSRDG 2278
++ G SG +T +V QD S ++G S+ + +Q+R
Sbjct: 225 ---ETVTG----SGTQTQAGATQTVEQD---------SSHQTGRTSKQTQEATNDQNRGT 268
Query: 2279 SRH--PRSHHEDRAGHGHSAESSRQSGTHHAENSSGGQAASSHEQARSSAGERHGSHHQQ 2336
H RS GH + Q+GTH + + SSH+ +S + Q+
Sbjct: 269 ETHGQGRSQTSQAVTGGH---AQIQAGTHTQTPTQTVEQDSSHQTGSTS------TQTQE 319
Query: 2337 SADSSRHSGIGHGQASSAVRDSGHRGSSGSQASDSEGHSEDSDTQSVSAHGQAGPHQQSH 2396
S + HGQ S + G + QA E +Q+VS HG G +Q
Sbjct: 320 STNGQNRGTEIHGQGRSQTSQAVTGGHTQIQAGSHTETVEQDRSQTVS-HG--GAREQGQ 376
Query: 2397 QESTRGRSAGRSGRSGSFLYQVSTHEQSESAHG---RTGTSTGGRQGSHHKQARDSSRHS 2453
++ G SG QVS E E+ G +TG ST G + R
Sbjct: 377 TQTQPG--------SGQRWMQVSNPEAGETVPGGQAQTGAST--ESGRQEWSSTHPRRCV 426
Query: 2454 TSQEG--QDTIHGHPGSSSGGRQGSHYEQLVDRSGHSGSHHSHTTSQGRSDA 2503
T +G Q T+ G R E ++ R H S +++QG+ A
Sbjct: 427 TEGQGDRQPTVVGEEWVDDHSR-----ETVILRLDQGNLHTSVSSAQGQDAA 473
Score = 53.1 bits (126), Expect = 5e-06
Identities = 78/371 (21%), Positives = 143/371 (38%), Gaps = 34/371 (9%)
Query: 723 SGTGHGQASSAVRDSGHRGSSGSQATDSEGHSEDSDTQSVSGHGQAGHHQQSHQES-ARD 781
S + G S S H G+S + + + + H + H+QS Q S ++
Sbjct: 90 SESAEGACGSQESGSLHSGAS-QELGEGQRSGTEVGRAGKGQHYEGSSHRQSQQGSRGQN 148
Query: 782 RSGERSRRSGSFLYQVSTHKQSESSHGWTGPSTGVRQGSHHEQARDNSRHSASQDGQDTI 841
R G +++ + VS++ + S S ++ EQ +Q +
Sbjct: 149 RPGVQTQGQATGSAWVSSYDRQAESQSQERISPQIQLSGQTEQ---------TQKAGEGK 199
Query: 842 RGHPGSSRRGRQGSHHEQSVDRSGHSGSHHSHTTSQGRSDASR--GQSGSRSASRTTRNE 899
R R RQ EQ DR+ +G + + +Q ++ A++ Q S RT++
Sbjct: 200 RNQTTEMRPERQPQTREQ--DRAHQTGETVTGSGTQTQAGATQTVEQDSSHQTGRTSKQT 257
Query: 900 EQSRDGSRHSGSRHHEASSHADISRHSQAGQGQSEGSRTSRRQGSSVSQDSDSEGHSEDS 959
+++ + H + S S+ G Q + ++ +V QDS + S +
Sbjct: 258 QEATNDQNRGTETHGQGRSQT--SQAVTGGHAQIQAGTHTQTPTQTVEQDSSHQTGSTST 315
Query: 960 ERWSGSASRNHRGS---AQEQSRHGSRHPRSHHEDRAG-HGHSADSSRQSGTPHAETSSG 1015
+ + +N RG+ Q +S+ H + +AG H + + R H G
Sbjct: 316 QTQESTNGQN-RGTEIHGQGRSQTSQAVTGGHTQIQAGSHTETVEQDRSQTVSH-----G 369
Query: 1016 GQAASSHEQARSSPGERHGSRHQQSADSSRHSGIPRRQA-SSAVRDSG--HWGSSGSQAS 1072
G A Q ++ PG G R Q ++ +P QA + A +SG W S+ +
Sbjct: 370 G--AREQGQTQTQPGS--GQRWMQVSNPEAGETVPGGQAQTGASTESGRQEWSSTHPRRC 425
Query: 1073 DSEGHSEESDT 1083
+EG + T
Sbjct: 426 VTEGQGDRQPT 436
Score = 50.4 bits (119), Expect = 3e-05
Identities = 82/395 (20%), Positives = 140/395 (35%), Gaps = 70/395 (17%)
Query: 2980 SHHQQSADSSRHSGIGHGQASSAVRDSGHRGYSGSQASDNEGHSEDSDTQSVSAHGQAGS 3039
S + A S+ SG H AS + + G +A + H + S
Sbjct: 90 SESAEGACGSQESGSLHSGASQELGEGQRSGTEVGRAGKGQ-------------HYEGSS 136
Query: 3040 HQQSHQES-ARGRSG-ETSGHSGSFLYQVSTHEQSESSHGWTGPSTRGRQGSRHEQAQDS 3097
H+QS Q S + R G +T G + + VS++++ S S + + + EQ Q +
Sbjct: 137 HRQSQQGSRGQNRPGVQTQGQATGSAW-VSSYDRQAESQSQERISPQIQLSGQTEQTQKA 195
Query: 3098 SRHSASQYGQDTIRGHPGSSRGGRQGYHHEHSVDSSGHSGSHHSHTTSQGRSDASRGQSG 3157
+Q + P +R + + +V SG T +Q + + Q
Sbjct: 196 GEGKRNQTTEMRPERQP-QTREQDRAHQTGETVTGSG--------TQTQAGATQTVEQDS 246
Query: 3158 SRSASRTTRNEEQSGDSSRHSVSRHHEASTHADISRHSQAVQG---QSEGSRRSRRQGSS 3214
S RT++ +++ + H + S+ SQAV G Q + ++ +
Sbjct: 247 SHQTGRTSKQTQEATNDQNRGTETHGQGR-----SQTSQAVTGGHAQIQAGTHTQTPTQT 301
Query: 3215 VSQDSDSEGHSEDSERWSGSASRNHRGSVQEQSRHGSRHPRSHHEDRAGHGHSADRSRQS 3274
V QDS + +GS S + S Q+R H G ++ Q+
Sbjct: 302 VEQDSSHQ---------TGSTSTQTQESTNGQNRGTEIH-----------GQGRSQTSQA 341
Query: 3275 GTRHAETSSGGQAASSHEQARSSPGERHGSRHQQSADSSRHSG--------------IPR 3320
T G + EQ RS G+R Q + SG +P
Sbjct: 342 VTGGHTQIQAGSHTETVEQDRSQTVSHGGAREQGQTQTQPGSGQRWMQVSNPEAGETVPG 401
Query: 3321 GQA---SSAVRDSRHWGSSGSQASDSEGHSEESDT 3352
GQA +S + W S+ + +EG + T
Sbjct: 402 GQAQTGASTESGRQEWSSTHPRRCVTEGQGDRQPT 436
Score = 43.5 bits (101), Expect = 0.004
Identities = 40/185 (21%), Positives = 75/185 (40%), Gaps = 22/185 (11%)
Query: 3797 SDASHGQSGSRS-------ASRETRNEEQSGDGSRHSGSRHHEASTQADSSRHSQSGQGE 3849
S+++ G GS+ AS+E ++SG +G H + S+ GQ
Sbjct: 90 SESAEGACGSQESGSLHSGASQELGEGQRSGTEVGRAGKGQHYEGSSHRQSQQGSRGQNR 149
Query: 3850 SAGSRRSRRQGSSVSQDSDSEAYPEDSERRSESASRNHHGSSREQSRDGSRH-------- 3901
+ + GS+ D +A + ER S + +++ +G R+
Sbjct: 150 PGVQTQGQATGSAWVSSYDRQAESQSQERISPQIQLSGQTEQTQKAGEGKRNQTTEMRPE 209
Query: 3902 --PGSSHRDTASHVQSSPVQSDSSTAKEHGHFSSLSQDSAYHSGIQSRGSPHSSSSYHYQ 3959
P + +D A Q+ + S T + G ++ QDS++ +G R S + + + Q
Sbjct: 210 RQPQTREQDRAH--QTGETVTGSGTQTQAGATQTVEQDSSHQTG---RTSKQTQEATNDQ 264
Query: 3960 SEGTE 3964
+ GTE
Sbjct: 265 NRGTE 269
>gi|239758013 PREDICTED: hypothetical protein [Homo sapiens]
Length = 819
Score = 100 bits (249), Expect = 3e-20
Identities = 153/764 (20%), Positives = 280/764 (36%), Gaps = 89/764 (11%)
Query: 314 SGSASRNHHGSAWEQSRD-GSRHPRSHDEDRASHGHSADSSRQSGTRHAETSSRGQTASS 372
+G +R H W+++ G R E +A+ A ++ G R + RGQ A++
Sbjct: 81 AGKEARQH----WQKAAGAGGAENRGGGEQKAA----AAGTKSLGGRGRKPRRRGQKAAA 132
Query: 373 H---------EQARSSPGERHGSGHQQSADSSRHSATG-----RGQASSAVSDRGHRGSS 418
+++ ++ + G+G Q++A ++ + G + A+ A S G +
Sbjct: 133 TGSKKPRWRAQKSAAAGSKNRGAGAQKAAAAAGVKSQGGEKPQKAAAAGAKSRSGKKPRR 192
Query: 419 GSQASDSEGHSENSDTQSVSGHGKA-GLRQQSHQESTRGRSGERSGRSGSSLYQVSTHEQ 477
S + + ++ S GK G R++ H+ G +S R G Q
Sbjct: 193 RGAKSRGDEDKKGRQREAKSRFGKTRGGRRKKHRRPKPAAGGAKSRRGGGKKPQKQRRRG 252
Query: 478 PDSAHG---RTGTSTGGRQGSHHEQARDSSRHSASQEGQDTIRGHPGS-SRGGRQGSHHE 533
+A G R G S GG Q ++++ A + G T P + RGGR
Sbjct: 253 QKAATGGKSRVGKSRGGGDKKLRRQGQNAALAGAKRRGAATAGEKPAAKGRGGR------ 306
Query: 534 QSVNRSGHSGSHHSHTTSQGRSDASHGQSGSRSASRQTRNEEQSGDGTRHSGSRHHEASS 593
S G + G+ G + R + + + GT+ G +A+
Sbjct: 307 --------------GPKSLGGQNPRWGRGGKKPRRRGQKATKAAAAGTKRGGGGQQKAAV 352
Query: 594 QADSSRHSQVGQGQ-------SSGPRTSRNQGSSVS-QDSDSQGHSEDSERWSGSASRNH 645
SR Q +G+ S+ SR G +++ +G RW R
Sbjct: 353 VGVKSRKKQRRRGKKPRRQKASAAGAKSRGGGDKKGLREAKRRGDGRKKPRWQNPRRRAQ 412
Query: 646 HGSAQEQSRDGSRHPRSH----HEDRAGHGHSADSS--RKSGTRHTQNSSSGQAASSHE- 698
A + GS+ PR + R G S R+ G + Q ++ A S +
Sbjct: 413 KAPAAKPRGGGSKKPRRRGPKAAKSRGGKSRSGGGKKPRRRGQKARQKAAEAGAESRGDK 472
Query: 699 ----QARSSAGER--------HGSRH---QLQSADSSRHSGTGHGQASSAVRDSGHRGSS 743
Q S+AG + H ++ + Q A+++ T G S + + +
Sbjct: 473 KQGRQKASAAGTKSRGGGLKSHSGKNLWRRGQKAEAAGEKATAAGAKSRGRKQPRRQKPA 532
Query: 744 GSQATDSEGHSEDSDTQSVSGHGQAGHHQQSHQESARDRSGERSRRSGSFLYQVSTHKQS 803
+ A G S+ Q G H +++S R G + R+ G T
Sbjct: 533 VAGAKSRVGGSKSRQRQKAVAAGATSHGGGGNKQS-RGGGGNKPRQWGQTAAAAKTRGGG 591
Query: 804 ESSHGWTGPSTGVRQGSHHEQARDNSRHSASQDGQDTIRGHPGSSRRGRQGSHHEQSVDR 863
+ GW + GV + + + R A+ G + R P RRG++ + +
Sbjct: 592 DKQPGWQKAAAGVTKSRSGDGGKKAWRQKAAGTGAKS-RKKPW--RRGQKDAAAAEKAWA 648
Query: 864 SGHSGSHHSHTTSQGRSDASRGQSGSRSA-----SRTTRNEEQSRDGSRHSGSRHHEASS 918
+G + + + A+ G S +A + + + R SR G ++
Sbjct: 649 TGATSRGSGGKQPRWQKPAAAGSESSAAAAVGQEAEARKKPRRRRAKSRGDGGQNAAVGI 708
Query: 919 HADISRHSQAGQGQSEGSRTSRRQGSSVSQDSDSEGHSEDSERWSGSASRNHRGSAQEQS 978
+ R + G+S G ++ +GS ++ S G S + +AS++H G ++
Sbjct: 709 NPWQRRGKKPRLGKSRGGGGAKSRGSGGAKSRGSGGAKSRSGK-KAAASKSHGGGGAKRR 767
Query: 979 RHGSRHPRSHHEDRAGHGHSADSSRQSGTPHAETSSG-GQAASS 1021
R G RS + G A ++ P ++ G GQ A++
Sbjct: 768 RGGGAKSRSGEKAVTAGGQKAAAAGGKKPPRVKSRGGRGQKAAA 811
Score = 89.7 bits (221), Expect = 5e-17
Identities = 163/852 (19%), Positives = 304/852 (35%), Gaps = 138/852 (16%)
Query: 2953 RHTQTSSGGQAASSHEQARSSAGERHGSHHQQSADSSRHSGIGHGQASSAVRDSGHRGYS 3012
R + ++GG+ A Q + AG+ H Q++A + G G+ +A +
Sbjct: 60 RRQKAAAGGKKARLRGQKGAVAGKEARQHWQKAAGAGGAENRGGGEQKAAA--------A 111
Query: 3013 GSQASDNEGHSEDSDTQSVSAHGQAGSHQQSHQESARGRSGETSGHSGSFLYQVSTHEQS 3072
G+++ G Q +A G ++ + +A G +G Q +
Sbjct: 112 GTKSLGGRGRKPRRRGQKAAATGSKKPRWRAQKSAAAGSKNRGAGA------QKAAAAAG 165
Query: 3073 ESSHGWTGPSTRGRQGSRHEQAQDSSRHSASQYGQDTIRGHP-------GSSRGGRQGYH 3125
S G P G++ + R A G + +G G +RGGR+ H
Sbjct: 166 VKSQGGEKPQKAAAAGAKSRSGKKPRRRGAKSRGDEDKKGRQREAKSRFGKTRGGRRKKH 225
Query: 3126 HEHSVDSSGHSGSHHSHTTSQGRSDASRGQSGSRSASRTTRNEEQSGDSSRHSVSRHHEA 3185
+ G + + RG R + +G SR SR
Sbjct: 226 RRPKPAAGG--------------AKSRRGGGKKPQKQRRRGQKAATGGKSRVGKSR---G 268
Query: 3186 STHADISRHSQAVQGQSEGSRRSRRQGSSVSQDSDSEGHSEDSERWSGSASRNHRGSVQE 3245
+ R QGQ+ ++R+G++ + + + + + G G
Sbjct: 269 GGDKKLRR-----QGQNAALAGAKRRGAATAGE-------KPAAKGRGGRGPKSLGGQNP 316
Query: 3246 QSRHGSRHPRSHHEDRAGHGHSADRSRQSGTRHAETSSGGQAASSHEQARSSPGERHGSR 3305
+ G + PR G A ++ +GT+ GGQ ++ +S +R
Sbjct: 317 RWGRGGKKPRRR-------GQKATKAAAAGTKRG---GGGQQKAAVVGVKSRKKQR---- 362
Query: 3306 HQQSADSSRHSGIPRGQASSAVRDSRHWGSSGSQASDSEGHSEESDTQSVSGHGQAGPHQ 3365
R PR Q +SA G+ D +G E G G+ P
Sbjct: 363 --------RRGKKPRRQKASAA------GAKSRGGGDKKGLREAKRR----GDGRKKPRW 404
Query: 3366 QSHQESARDRSGGRSGRSGSFLYQVSTHEQSESAHGRTRTSTGRRQGSHHEQARDSSRHS 3425
Q+ + A+ + GS + + ++S G++R+ G++ ++AR + +
Sbjct: 405 QNPRRRAQKAPAAKPRGGGSKKPRRRGPKAAKSRGGKSRSGGGKKPRRRGQKARQKAAEA 464
Query: 3426 ASQEGQDTIRGHPGSSRRGRQGSHYEQSVDRSGHSGSHHSHTT-SQGRSDASRGQ----S 3480
++ G ++GRQ + + R G SH +G+ + G+ +
Sbjct: 465 GAESR--------GDKKQGRQKASAAGTKSRGGGLKSHSGKNLWRRGQKAEAAGEKATAA 516
Query: 3481 GSRSASR-QTRNDEQSGDGSRH----SWSHHHEASTQADSSRHSQSGQGQSAGPRTSR-N 3534
G++S R Q R + + G++ S S + + A ++ H G QS G ++
Sbjct: 517 GAKSRGRKQPRRQKPAVAGAKSRVGGSKSRQRQKAVAAGATSHGGGGNKQSRGGGGNKPR 576
Query: 3535 QGSSVSQDSDSQGHSEDSERWSGSA-----SRNHRGS--AQEQSRDGSRHPTSHHEDRAG 3587
Q + + ++G + W +A SR+ G A Q G+ + R G
Sbjct: 577 QWGQTAAAAKTRGGGDKQPGWQKAAAGVTKSRSGDGGKKAWRQKAAGTGAKSRKKPWRRG 636
Query: 3588 HGHSAESSRQSGTHHAENSSGGQ--------AASSHEQARSSAGERHGSHHQQSADSSRH 3639
+A + + T SGG+ AA S A ++ G+ + + ++
Sbjct: 637 QKDAAAAEKAWATGATSRGSGGKQPRWQKPAAAGSESSAAAAVGQEAEARKKPRRRRAKS 696
Query: 3640 SGIGHGQASSAV----------RDSGHRGSSGSQASDSEGHSEDSDTQSVSAHGQAGPHQ 3689
G G A+ + R RG G+++ S G + S G+
Sbjct: 697 RGDGGQNAAVGINPWQRRGKKPRLGKSRGGGGAKSRGSGGAKSRGSGGAKSRSGKKAAAS 756
Query: 3690 QSH--QESTRGRSAGRSGRSGSFLYQVSTHEQSESAHGRAGPSTGGRQGSRHEQARDSSR 3747
+SH + R R G RSG E++ +A G+ + GG++ R ++R
Sbjct: 757 KSHGGGGAKRRRGGGAKSRSG---------EKAVTAGGQKAAAAGGKKPPR-VKSRGGRG 806
Query: 3748 HSASQEGQDTIR 3759
A+ G+ +R
Sbjct: 807 QKAAAGGKKPLR 818
Score = 86.7 bits (213), Expect = 4e-16
Identities = 143/765 (18%), Positives = 272/765 (35%), Gaps = 83/765 (10%)
Query: 1623 REQSRHGSRNPRSHQEDRASHGHSAESSRQ--SGTRHAETSSGGQ--AASSQEQARSSPG 1678
R+++ G + R + A G A Q +G AE GG+ AA++ ++ G
Sbjct: 61 RQKAAAGGKKARLRGQKGAVAGKEARQHWQKAAGAGGAENRGGGEQKAAAAGTKSLGGRG 120
Query: 1679 ERHGSRHQQSADSSTDSGTGRRQDSSVVGDSGNRGSSGSQAS-----DSEGHSEESDTQS 1733
+ R Q++A + + R Q S+ G S NRG+ +A+ S+G + +
Sbjct: 121 RKPRRRGQKAAATGSKKPRWRAQKSAAAG-SKNRGAGAQKAAAAAGVKSQGGEKPQKAAA 179
Query: 1734 VSAHGQAGPHQQSHQESTRGQSGERSGRSGSFLYQVSTHEQSESAHGRTGPSTGGRQRSR 1793
A ++G + +RG ++ + + T H R P+ GG + R
Sbjct: 180 AGAKSRSGKKPRRRGAKSRGDEDKKGRQREAKSRFGKTRGGRRKKHRRPKPAAGGAKSRR 239
Query: 1794 HEQARDSSRHSASQEGQDTIRGHPGSSRGGRQGSHYEQSVDSSGHSGSHHSHTTSQERSD 1853
+ + Q+ + G SRGG Q +++ T+ E+
Sbjct: 240 GGGKKPQKQRRRGQKAATGGKSRVGKSRGGGDKKLRRQGQNAALAGAKRRGAATAGEKPA 299
Query: 1854 VS-RGQSGSRSVSRQT---------------RNEKQSGDGSRHSGSRHHEASSRADSSRH 1897
RG G +S+ Q + K + G++ G +A+ SR
Sbjct: 300 AKGRGGRGPKSLGGQNPRWGRGGKKPRRRGQKATKAAAAGTKRGGGGQQKAAVVGVKSRK 359
Query: 1898 SQVGQGQ-------SSGPRTSRNQGSSVS-QDSDSQGHSEDSERWS-------------- 1935
Q +G+ S+ SR G +++ +G RW
Sbjct: 360 KQRRRGKKPRRQKASAAGAKSRGGGDKKGLREAKRRGDGRKKPRWQNPRRRAQKAPAAKP 419
Query: 1936 ---GSASRNHLGSAWEQSRDGSRHPGSHHEDRAGHGHSADSSRQSG--TRHTESSSRGQA 1990
GS G +SR G G + R + + ++G +R + R +A
Sbjct: 420 RGGGSKKPRRRGPKAAKSRGGKSRSGGGKKPRRRGQKARQKAAEAGAESRGDKKQGRQKA 479
Query: 1991 ASSHEQARSSAGERHGSHH---QLQSADSSRHSGIGHGQASSAVRDSGHRGYSGSQASDS 2047
+++ ++R + H + + Q A+++ G S + + + + A
Sbjct: 480 SAAGTKSRGGGLKSHSGKNLWRRGQKAEAAGEKATAAGAKSRGRKQPRRQKPAVAGAKSR 539
Query: 2048 EGHSEDSDTQSVSAQGKAGPHQQSHKESARGQSGESSGRSGSFLYQVSTHEQSESTHGQS 2107
G S+ Q A G A H + +RG G + G T + G
Sbjct: 540 VGGSKSRQRQKAVAAG-ATSHGGGGNKQSRGGGGNKPRQWGQTAAAAKTRGGGDKQPGWQ 598
Query: 2108 APSTGGRQGSHYDQAQDSSRHSASQEGQDTIRGHPGPSRGGRQGSHQEQSVDRSGHSGSH 2167
+ G + D + + R A+ G + + + R+G + +++ +G+
Sbjct: 599 KAAAGVTKSRSGDGGKKAWRQKAAGTGAKSRK------KPWRRGQKDAAAAEKAWATGA- 651
Query: 2168 HSHTTSQGRSDAS-RGQSGSRSASRKTYDKEQSGDGSRHSGSHHHEASSWADSSRHSLVG 2226
TS+G R Q + + S + + A S D +++ VG
Sbjct: 652 ----TSRGSGGKQPRWQKPAAAGSESSAAAAVGQEAEARKKPRRRRAKSRGDGGQNAAVG 707
Query: 2227 ------------QGQSSGPRTSRPRGSSVSQDSDSEGHSEDSERRSGSASRNHHGSAQEQ 2274
G+S G ++ RGS ++ S G S +++ +AS++H G ++
Sbjct: 708 INPWQRRGKKPRLGKSRGGGGAKSRGSGGAKSRGSGGAKSRSGKKA-AASKSHGGGGAKR 766
Query: 2275 SRDGSRHPRSHHEDRAGHGHSAESSRQSGTHHAENSSG-GQAASS 2318
R G RS + G A ++ ++ G GQ A++
Sbjct: 767 RRGGGAKSRSGEKAVTAGGQKAAAAGGKKPPRVKSRGGRGQKAAA 811
Score = 79.7 bits (195), Expect = 5e-14
Identities = 178/929 (19%), Positives = 340/929 (36%), Gaps = 154/929 (16%)
Query: 771 HQQSHQESARDRSGERSRRSGSFLYQVSTHKQSESSH-GWTGPSTGVR-QGSHHEQARDN 828
H+Q +Q + R G G+ L + +ES+ + + GV+ GS ++ R
Sbjct: 6 HRQCNQAAGRAGPGAPL---GAALARTPVELAAESAAPALSAAAAGVKILGSGDKKLR-- 60
Query: 829 SRHSASQDGQDT-IRGHPGSSRRGRQGSHHEQSVDRSG----HSGSHHSHTTS------- 876
R A+ G+ +RG G+ G++ H Q +G G +
Sbjct: 61 -RQKAAAGGKKARLRGQKGAVA-GKEARQHWQKAAGAGGAENRGGGEQKAAAAGTKSLGG 118
Query: 877 QGRSDASRGQSGSRSASRTTR--NEEQSRDGSRHSGSRHHEASSHADISRHSQAGQ---- 930
+GR RGQ + + S+ R ++ + GS++ G+ +A++ A + SQ G+
Sbjct: 119 RGRKPRRRGQKAAATGSKKPRWRAQKSAAAGSKNRGAGAQKAAAAAGVK--SQGGEKPQK 176
Query: 931 -----GQSEGSRTSRRQGSSVSQDSDSEGHSEDSERWSGSASRNHRGSAQEQSRHGSRHP 985
+S + RR+G+ D D +G +++ G ++R G R
Sbjct: 177 AAAAGAKSRSGKKPRRRGAKSRGDEDKKGRQREAKSRFG------------KTRGGRRKK 224
Query: 986 RSHHEDRAGHGHSADSSRQSGTPHAETSSGGQAASSHEQARSSPGERHGSRH-QQSADSS 1044
+ AG A S R G + GQ A++ ++R G + ++ ++
Sbjct: 225 HRRPKPAAG---GAKSRRGGGKKPQKQRRRGQKAATGGKSRVGKSRGGGDKKLRRQGQNA 281
Query: 1045 RHSGIPRRQASSAVRDSGHWGSSGSQASDSEGHSEESDTQSVSGHGQDGPHQQSHQESAR 1104
+G RR A++A G G G + G G P ++ + +
Sbjct: 282 ALAGAKRRGAATAGEKPAAKGRGGRGPKSLGGQNPRW------GRGGKKPRRRGQKATKA 335
Query: 1105 DWSGGRSGRSGSFIYQVSTHEQSESAHGRTRTSTGRRQGSHHEQARDSSRHSASQEGQDT 1164
+G + G G +Q + G RR+G + + S+ + S+ G D
Sbjct: 336 AAAGTKRGGGG---------QQKAAVVGVKSRKKQRRRGKKPRRQKASAAGAKSRGGGDK 386
Query: 1165 IRAHPGSRRGGRQGSHHEQSVDRSGHSGSHHSHTTSQGRSDASHGQSGSRSASRQTRKDK 1224
RRG + Q+ R + G ++S ++R
Sbjct: 387 KGLREAKRRGDGRKKPRWQNPRRRAQKAPAAKPRGGGSKKPRRRGPKAAKSRGGKSRSGG 446
Query: 1225 QSGDGSRHSGSRHHEAASWADSSRHSQVGQEQSSGSRTSRHQGSSVSQDSDSERHSDDSE 1284
R +R A + A+S + G++++S + T G S HS +
Sbjct: 447 GKKPRRRGQKARQKAAEAGAESRGDKKQGRQKASAAGTKSRGGGLKS-------HSGKNL 499
Query: 1285 RLSGSASRNHHGSSREQSRDGSRHPGFHQEDRASHGHSADSSRQSGTHHTESSSHGQAVS 1344
G + + + + G++ G Q R + SR G ++S +AV
Sbjct: 500 WRRGQKA---EAAGEKATAAGAKSRGRKQPRRQKPAVAGAKSRVGG---SKSRQRQKAV- 552
Query: 1345 SHEQARSSPGERHGSRHQQSADSSRHSGIGHRQASSAVRDSGHRGSSGSQVTNSEGHSED 1404
+A ++ H G G++Q+ RG G++ +
Sbjct: 553 -------------------AAGATSHGGGGNKQS---------RGGGGNK------PRQW 578
Query: 1405 SDTQSVSAHGQAGPHQQSHKESARGQSGESSGRSRSFLYQVSSHEQSESTHGQTAPSTGG 1464
T + + G Q +++A G + SG + + Q A TG
Sbjct: 579 GQTAAAAKTRGGGDKQPGWQKAAAGVTKSRSG------------DGGKKAWRQKAAGTGA 626
Query: 1465 RQGSRHEQARNSSRHSASQDGQDTIRGHPGSSRGGRQGSYHEQSVDRSGHSGYHHSHTTP 1524
+ SR + R + +A+ + + G GG+Q + + + S
Sbjct: 627 K--SRKKPWRRGQKDAAAAE-KAWATGATSRGSGGKQPRWQKPAAAGS------------ 671
Query: 1525 QGRSDASHGQSGPRSASRQTRNEEQSGDGSRHSGSRHHEPSTRAGSSRHSQVGQGESAGS 1584
+ + A+ GQ + R + GDG +++ + P R G + ++G+ G
Sbjct: 672 ESSAAAAVGQEAEARKKPRRRRAKSRGDGGQNAAVGIN-PWQRRG--KKPRLGKSRGGGG 728
Query: 1585 KTSRRQGSSVSQDRDSEGHSEDSERRSESASRNHYGSAREQSRHGSRNPRSHQEDRASHG 1644
SR GS ++ R S G S +++ +AS++H G ++ R G RS ++ + G
Sbjct: 729 AKSR--GSGGAKSRGSGGAKSRSGKKA-AASKSHGGGGAKRRRGGGAKSRSGEKAVTAGG 785
Query: 1645 HSAESS--------RQSGTRHAETSSGGQ 1665
A ++ + G R + ++GG+
Sbjct: 786 QKAAAAGGKKPPRVKSRGGRGQKAAAGGK 814
Score = 79.0 bits (193), Expect = 9e-14
Identities = 146/776 (18%), Positives = 282/776 (36%), Gaps = 107/776 (13%)
Query: 2272 QEQSRDGSRHPRSHHEDRAGHGHSAESSRQ--SGTHHAENSSGGQ--AASSHEQARSSAG 2327
++++ G + R + A G A Q +G AEN GG+ AA++ ++ G
Sbjct: 61 RQKAAAGGKKARLRGQKGAVAGKEARQHWQKAAGAGGAENRGGGEQKAAAAGTKSLGGRG 120
Query: 2328 ERHGSHHQQSADSSRHSGIGHGQASSAVRDSGHRGSSGSQASDSEGHSEDSDTQSVSAHG 2387
+ Q++A + Q S+A S +RG+ +A+ + G + A
Sbjct: 121 RKPRRRGQKAAATGSKKPRWRAQKSAAA-GSKNRGAGAQKAAAAAGVKSQGGEKPQKAAA 179
Query: 2388 QAGPHQQSHQESTRG-RSAGRSGRSGSFLYQVSTHEQSESAHGRTGTSTGGRQGSHH--- 2443
+ + RG +S G + G + A R G + GGR+ H
Sbjct: 180 AGAKSRSGKKPRRRGAKSRGDEDKKG----------RQREAKSRFGKTRGGRRKKHRRPK 229
Query: 2444 ------KQARDSSRHSTSQEGQDTIHGHPGSSSGGRQGSHYEQLVDRSGHS----GSHHS 2493
K R + Q + G S G+ ++ + R G + G+
Sbjct: 230 PAAGGAKSRRGGGKKPQKQRRRGQKAATGGKSRVGKSRGGGDKKLRRQGQNAALAGAKRR 289
Query: 2494 HTTSQGRSDASHGHSGSRSASRQTRNDEQSGDGSRHSGSRHHEASSRADSSGHSQVGQGQ 2553
+ G A+ G G S +N G + R + +++A ++G + G GQ
Sbjct: 290 GAATAGEKPAAKGRGGRGPKSLGGQNPRWGRGGKKPR--RRGQKATKAAAAGTKRGGGGQ 347
Query: 2554 SEGPRTSRNWGSSFSQDSDSQGHSEDSERWSGSASRNHHGSAQEQLR------DGSRHPR 2607
+ G + +G ++ S + +++ G ++ LR DG + PR
Sbjct: 348 QKAAVV----GVKSRKKQRRRGKKPRRQKASAAGAKSRGGGDKKGLREAKRRGDGRKKPR 403
Query: 2608 SHQEDRAGHGHSADSSRQSGTRHTQTSSGGQAASSHEQARSSAGERHGSHHQQSADSSRH 2667
R A R G++ + A S ++RS G++ Q++ +
Sbjct: 404 WQNPRRRAQKAPAAKPRGGGSKKPRRRGPKAAKSRGGKSRSGGGKKPRRRGQKARQKAAE 463
Query: 2668 SGI--------GHGQASSA---VRDSGHRGYSGSQASDNEGHSEDSDTQSVSAHGQA-GS 2715
+G G +AS+A R G + +SG +E + ++ +A ++ G
Sbjct: 464 AGAESRGDKKQGRQKASAAGTKSRGGGLKSHSGKNLWRRGQKAEAAGEKATAAGAKSRGR 523
Query: 2716 HQQSHQESARGRSGETSGHSGSFLYQVSTHEQSESSHGWTGPSTRGRQGSRHEQAQDSSR 2775
Q Q+ A + G S S Q + + S G +RG G++ Q ++
Sbjct: 524 KQPRRQKPAVAGAKSRVGGSKSRQRQKAVAAGATSHGGGGNKQSRGGGGNKPRQWGQTAA 583
Query: 2776 HSASQDGQDTIRG---------HPGSSRGGRQGYHHEHSVDSSGHSGSHHSHTTSQGRSD 2826
+ ++ G D G S GG++ + + ++G +G+ D
Sbjct: 584 AAKTRGGGDKQPGWQKAAAGVTKSRSGDGGKKAWRQK----AAGTGAKSRKKPWRRGQKD 639
Query: 2827 ASR-------GQSGSRSASRTTRNEEQSGDGSRHSGS-------------RHHEASTHAD 2866
A+ G + S + R ++ + GS S + R A + D
Sbjct: 640 AAAAEKAWATGATSRGSGGKQPRWQKPAAAGSESSAAAAVGQEAEARKKPRRRRAKSRGD 699
Query: 2867 ISRHS------------QAVQGQSEGSRRSRRQGSSVSQDSDSEGHSEDSERWSGSASRN 2914
+++ + G+S G ++ +GS ++ S G S + +AS++
Sbjct: 700 GGQNAAVGINPWQRRGKKPRLGKSRGGGGAKSRGSGGAKSRGSGGAKSRSGK-KAAASKS 758
Query: 2915 HHGSAQEQLRDGSRHPRSHQEDRAGHGHSADSS--------RQSGTRHTQTSSGGQ 2962
H G ++ R G RS ++ G A ++ + G R + ++GG+
Sbjct: 759 HGGGGAKRRRGGGAKSRSGEKAVTAGGQKAAAAGGKKPPRVKSRGGRGQKAAAGGK 814
Score = 76.6 bits (187), Expect = 5e-13
Identities = 163/835 (19%), Positives = 286/835 (34%), Gaps = 130/835 (15%)
Query: 2629 RHTQTSSGGQAASSHEQARSSAGERHGSHHQQSADSSRHSGIGHGQASSAVRDSGHRGYS 2688
R + ++GG+ A Q + AG+ H Q++A + G G+ +A +
Sbjct: 60 RRQKAAAGGKKARLRGQKGAVAGKEARQHWQKAAGAGGAENRGGGEQKAAA--------A 111
Query: 2689 GSQASDNEGHSEDSDTQSVSAHGQAGSHQQSHQESARGRSGETSGHSGSFLYQVSTHEQS 2748
G+++ G Q +A G ++ + +A G +G Q +
Sbjct: 112 GTKSLGGRGRKPRRRGQKAAATGSKKPRWRAQKSAAAGSKNRGAG------AQKAAAAAG 165
Query: 2749 ESSHGWTGPSTRGRQGSRHEQAQDSSRHSASQDGQDTIRGHP-------GSSRGGRQGYH 2801
S G P G++ + R A G + +G G +RGGR+ H
Sbjct: 166 VKSQGGEKPQKAAAAGAKSRSGKKPRRRGAKSRGDEDKKGRQREAKSRFGKTRGGRRKKH 225
Query: 2802 HEHSVDSSG-----HSGSHHSHTTSQGRSDASRGQS--------GSRSASRTTRNEEQSG 2848
+ G G +G+ A+ G+S G + R +N +G
Sbjct: 226 RRPKPAAGGAKSRRGGGKKPQKQRRRGQKAATGGKSRVGKSRGGGDKKLRRQGQNAALAG 285
Query: 2849 DGSRHSGSRHHEASTHADISRHSQAVQGQS----EGSRRSRRQGSSVSQ----DSDSEGH 2900
R + + + + R +++ GQ+ G ++ RR+G ++ + G
Sbjct: 286 AKRRGAATAGEKPAAKGRGGRGPKSLGGQNPRWGRGGKKPRRRGQKATKAAAAGTKRGGG 345
Query: 2901 SEDSERWSGSASRNHHGSAQEQLRDGSRHPRSHQEDRAGHGHSADSSRQSGTRHTQTSSG 2960
+ G SR ++Q R G + PR + AG S + G R +
Sbjct: 346 GQQKAAVVGVKSR------KKQRRRGKK-PRRQKASAAG-AKSRGGGDKKGLREAKRRGD 397
Query: 2961 GQAASSHEQARSSAGERHGSHHQQSADSSRHSGIG----HGQASSAVRDSGHRGYS-GSQ 3015
G+ + R A Q A +++ G G + A + G + S G +
Sbjct: 398 GRKKPRWQNPRRRA---------QKAPAAKPRGGGSKKPRRRGPKAAKSRGGKSRSGGGK 448
Query: 3016 ASDNEGHSEDSDTQSVSAHGQAGSHQQSHQESARG---RSGETSGHSGSFLYQVSTHEQS 3072
G A + Q + SA G R G HSG L++ ++
Sbjct: 449 KPRRRGQKARQKAAEAGAESRGDKKQGRQKASAAGTKSRGGGLKSHSGKNLWRRGQKAEA 508
Query: 3073 ESSHGW-TGPSTRGRQGSRHEQ-----AQDSSRHSASQYGQDTIRGHPGSSRGGRQGYHH 3126
G +RGR+ R ++ A+ S S+ Q + S GG
Sbjct: 509 AGEKATAAGAKSRGRKQPRRQKPAVAGAKSRVGGSKSRQRQKAVAAGATSHGGGGNKQSR 568
Query: 3127 EHSVDSSGHSGSHHSHTTSQGRSDASRGQSGSRSASRTTRNEEQSGDSSRHSVSRHHEAS 3186
+ G + ++G D G ++A+ T++ +SGD + R A
Sbjct: 569 GGGGNKPRQWGQTAAAAKTRGGGDKQPG--WQKAAAGVTKS--RSGDGGK-KAWRQKAAG 623
Query: 3187 THADISRHSQAVQGQSEGSRRSRRQGSSVSQDSDSEGHSEDSERWSGSASRNHRGSVQEQ 3246
T A SR +GQ + + + + + S G RW A+ S
Sbjct: 624 TGAK-SRKKPWRRGQKDAAAAEKAWATGAT----SRGSGGKQPRWQKPAAAGSESSA--- 675
Query: 3247 SRHGSRHPRSHHEDRAGHGHSADRSRQSGTRHAET-SSGGQAASSHEQARSSPGERHGSR 3305
A G A+ ++ R A++ GGQ A+ +P +R G +
Sbjct: 676 --------------AAAVGQEAEARKKPRRRRAKSRGDGGQNAA----VGINPWQRRGKK 717
Query: 3306 HQQSADSSRHSGIPRGQASSAVRDSRHWGSSGSQASDSEGHSEESDTQSVS--GHGQAGP 3363
PR S ++ GS G+++ S G S ++ + HG G
Sbjct: 718 -------------PRLGKSRGGGGAKSRGSGGAKSRGSGGAKSRSGKKAAASKSHGGGG- 763
Query: 3364 HQQSHQESARDRSGGRSGRSGSFLYQVSTHEQSESAHGRTRTSTGRRQGSHHEQA 3418
+ R R GG RSG V+ Q +A G + + +G ++A
Sbjct: 764 -------AKRRRGGGAKSRSGE--KAVTAGGQKAAAAGGKKPPRVKSRGGRGQKA 809
Score = 72.8 bits (177), Expect = 7e-12
Identities = 143/750 (19%), Positives = 265/750 (35%), Gaps = 105/750 (14%)
Query: 3207 RSRRQGSSVSQDSDSEGHSEDSERWSGSASRNHRGSVQEQSRHGSRHPRSHHEDRAGHGH 3266
R Q ++ + +++ G E +G+ S RG R PR + A G
Sbjct: 86 RQHWQKAAGAGGAENRGGGEQKAAAAGTKSLGGRG----------RKPRRRGQKAAATGS 135
Query: 3267 SADRSRQSGTRHAETSSGGQAASSHEQARSSPGERHGSRHQQSADSSRHSGIPRGQASSA 3326
R R + A S + A + + A ++ + G Q A ++ G S +
Sbjct: 136 KKPRWRAQ--KSAAAGSKNRGAGAQKAAAAAGVKSQGGEKPQKAAAA-------GAKSRS 186
Query: 3327 VRDSRHWGSSGSQASDSEGHSEESDTQSVSGHGQAGPHQQSHQESARDRSGGRSGRSGSF 3386
+ R G+ D +G E+ +S G + G ++ H+ G +S R G
Sbjct: 187 GKKPRRRGAKSRGDEDKKGRQREA--KSRFGKTRGG-RRKKHRRPKPAAGGAKSRRGGGK 243
Query: 3387 LYQVSTHE-QSESAHGRTRTSTGRRQGSH--HEQARDSSRHSASQEGQDTIRGHPGSSRR 3443
Q Q + G++R R G Q ++++ A + G T P + R
Sbjct: 244 KPQKQRRRGQKAATGGKSRVGKSRGGGDKKLRRQGQNAALAGAKRRGAATAGEKPAAKGR 303
Query: 3444 GRQGSHYEQSVDRSGHSGSHHSHTTSQGRSDASRGQSGSRSASRQTRNDEQSGDGSRHSW 3503
G +G G + G+ RGQ +++A+ T+ + G G +
Sbjct: 304 GGRGPK---------SLGGQNPRWGRGGKKPRRRGQKATKAAAAGTK---RGGGGQQ--- 348
Query: 3504 SHHHEASTQADSSRHSQSGQGQ-------SAGPRTSRNQGSSVS-QDSDSQGHSEDSERW 3555
+A+ SR Q +G+ SA SR G +++ +G RW
Sbjct: 349 ----KAAVVGVKSRKKQRRRGKKPRRQKASAAGAKSRGGGDKKGLREAKRRGDGRKKPRW 404
Query: 3556 SGSASRNHRGSAQEQSRDGSRHPTSHHEDRAGHGHSAESSRQSGTHHAENSSGGQAASSH 3615
R + A + GS+ P +A +S G + ++
Sbjct: 405 QNPRRRAQKAPAAKPRGGGSKKPR-RRGPKAAKSRGGKSRSGGGKKPRRRGQKARQKAAE 463
Query: 3616 EQARSSAGERHGSHHQQSADSSRHSGIGHGQASSAVRDSGHRGSSGSQASDSEGHSEDSD 3675
A S ++ G +Q A ++ G G S + ++ RG +E E +
Sbjct: 464 AGAESRGDKKQG---RQKASAAGTKSRGGGLKSHSGKNLWRRGQK------AEAAGEKAT 514
Query: 3676 TQSVSAHGQAGPHQQ----SHQESTRGRSAGRSGRSGSFLYQVSTHEQSESAHGRAGPST 3731
+ G+ P +Q + +S G S R R + ++H + R G
Sbjct: 515 AAGAKSRGRKQPRRQKPAVAGAKSRVGGSKSRQ-RQKAVAAGATSHGGGGNKQSRGGGGN 573
Query: 3732 GGRQGSRHEQARDSSRHSASQEG-QDTIRGHPGSRRG-GRQGSYHEQSVDRSGHSGSHHS 3789
RQ + A + Q G Q G SR G G + ++ +++ +G
Sbjct: 574 KPRQWGQTAAAAKTRGGGDKQPGWQKAAAGVTKSRSGDGGKKAWRQKA---AGTGAKSRK 630
Query: 3790 HTTSQGRSDASH-------GQSGSRSASRETRNEEQSGDGSRHSGS-------------R 3829
+G+ DA+ G + S ++ R ++ + GS S + R
Sbjct: 631 KPWRRGQKDAAAAEKAWATGATSRGSGGKQPRWQKPAAAGSESSAAAAVGQEAEARKKPR 690
Query: 3830 HHEASTQADSSRHSQSG------------QGESAGSRRSRRQGSSVSQDSDSEAYPEDSE 3877
A ++ D +++ G G+S G ++ +GS ++ S S
Sbjct: 691 RRRAKSRGDGGQNAAVGINPWQRRGKKPRLGKSRGGGGAKSRGSGGAKSRGSGGAKSRSG 750
Query: 3878 RRSESASRNHHGSSREQSRDGSRHPGSSHR 3907
+++ +AS++H G ++ R G S +
Sbjct: 751 KKA-AASKSHGGGGAKRRRGGGAKSRSGEK 779
Score = 70.1 bits (170), Expect = 4e-11
Identities = 139/681 (20%), Positives = 241/681 (35%), Gaps = 101/681 (14%)
Query: 258 ERSRSSDGKSSSQVNRSRHENTSQVPLQESRTRKRRGSRVSQDRDSEGHSEDSERHSGSA 317
+++ ++ G S + + + + + +RRG++ D D +G +++ G
Sbjct: 158 QKAAAAAGVKSQGGEKPQKAAAAGAKSRSGKKPRRRGAKSRGDEDKKGRQREAKSRFG-- 215
Query: 318 SRNHHGSAWEQSRDGSRHPRSHDEDRASHGHSADSSRQSGTRHAETSSRGQTASSHEQAR 377
++R G R + H + + G A S R G + + RGQ A++ +
Sbjct: 216 ----------KTRGGRR--KKHRRPKPAAG-GAKSRRGGGKKPQKQRRRGQKAAT--GGK 260
Query: 378 SSPGERHGSG----HQQSADSSRHSATGRGQASS----AVSDRGHRG--SSGSQ------ 421
S G+ G G +Q +++ A RG A++ A RG RG S G Q
Sbjct: 261 SRVGKSRGGGDKKLRRQGQNAALAGAKRRGAATAGEKPAAKGRGGRGPKSLGGQNPRWGR 320
Query: 422 ASDSEGHSENSDTQSVSGHGKAGLRQQSHQESTRGRSGERSGRSGSSLYQVSTHEQPDSA 481
T++ + K G Q +S ++ R G Q SA
Sbjct: 321 GGKKPRRRGQKATKAAAAGTKRGGGGQQKAAVVGVKSRKKQRRRGK-----KPRRQKASA 375
Query: 482 HGRTGTSTGGRQGSHHEQARDSSR-----HSASQEGQDTIRGHP---GSSRGGRQGSHHE 533
G G ++G + R R + + Q P GS + R+G
Sbjct: 376 AGAKSRGGGDKKGLREAKRRGDGRKKPRWQNPRRRAQKAPAAKPRGGGSKKPRRRGPKAA 435
Query: 534 QS---VNRSGHSGSHHSHTTSQGRSDASHGQSGSRSASRQTRNEEQSGDGTR-------- 582
+S +RSG G + R A+ + SR +Q R ++ S GT+
Sbjct: 436 KSRGGKSRSG-GGKKPRRRGQKARQKAAEAGAESRGDKKQGR-QKASAAGTKSRGGGLKS 493
Query: 583 HSGSRHHEASSQADSSRHSQVGQG-QSSGPRTSRNQGSSVSQDSDSQGHSEDSERWSGSA 641
HSG +A+++ G +S G + R Q +V+ G S+ +R A
Sbjct: 494 HSGKNLWRRGQKAEAAGEKATAAGAKSRGRKQPRRQKPAVAGAKSRVGGSKSRQRQKAVA 553
Query: 642 --SRNHHGSAQEQSR-DGSRHPRSHHEDRAGHGHSADSSRKSGTRHTQNSSSGQAASSHE 698
+ +H G +QSR G PR G +A +++ G Q AA +
Sbjct: 554 AGATSHGGGGNKQSRGGGGNKPRQ-------WGQTAAAAKTRGGGDKQPGWQKAAAGVTK 606
Query: 699 QARSSAGERHGSRHQLQSADSSRHSGTGHGQASSAVRDSG------HRGSSGSQATDSEG 752
G++ + + SR GQ +A + RGS G Q +
Sbjct: 607 SRSGDGGKKAWRQKAAGTGAKSRKKPWRRGQKDAAAAEKAWATGATSRGSGGKQPRWQKP 666
Query: 753 HSEDSDTQSVSGHGQAGHHQQSHQESARDRSGERSRRSGSFLYQVSTHKQSESSHGWTGP 812
+ S++ + + GQ A R R RR+ S G G
Sbjct: 667 AAAGSESSAAAAVGQ----------EAEARKKPRRRRA--------------KSRGDGGQ 702
Query: 813 STGVRQGSHHEQARDNSRHSASQDGQDTIRGHPGSSRRGRQGSHHEQSVDRSGHSGSHHS 872
+ V + + + G RG G+ RG G +S ++ S SH
Sbjct: 703 NAAVGINPWQRRGKKPRLGKSRGGGGAKSRGSGGAKSRG-SGGAKSRSGKKAAASKSHGG 761
Query: 873 HTTSQGRSDASRGQSGSRSAS 893
+ R ++ +SG ++ +
Sbjct: 762 GGAKRRRGGGAKSRSGEKAVT 782
Score = 65.5 bits (158), Expect = 1e-09
Identities = 120/659 (18%), Positives = 237/659 (35%), Gaps = 92/659 (13%)
Query: 97 SGHKHRKHSHHDKHEDNKQEENKENRKRPSSLERRNNRKGNKGRSKSPRETGG-----KR 151
SG K R+ ++ +E+K+ R+R + R G + + + P+ G +
Sbjct: 186 SGKKPRRRG-----AKSRGDEDKKGRQREAKSRFGKTRGGRRKKHRRPKPAAGGAKSRRG 240
Query: 152 HESSSEKKERKGY-SPTHREEEYGKNHHNSSKKEKNKTENTRLGDNRKRLSERLEEKEDN 210
+K+ R+G + T + GK+ KK + + +N L ++R + EK
Sbjct: 241 GGKKPQKQRRRGQKAATGGKSRVGKSRGGGDKKLRRQGQNAALAGAKRRGAATAGEKPAA 300
Query: 211 E-EGVYDYENTGRMTQKWIQSGHIATYYTIQDEAYDTTDSLLEENKIYERSRSSDGKSSS 269
+ G ++ G +W + G K R + + +++
Sbjct: 301 KGRGGRGPKSLGGQNPRWGRGG----------------------KKPRRRGQKATKAAAA 338
Query: 270 QVNR--SRHENTSQVPLQESRTRKRRGSRVSQDRDSEGHSEDSERHSGSASRNHHGSAWE 327
R + + V ++ + ++RRG + + + S + G + A +
Sbjct: 339 GTKRGGGGQQKAAVVGVKSRKKQRRRGKKPRRQKASAA----GAKSRGGGDKKGLREA-K 393
Query: 328 QSRDGSRHPRSHDEDRASHGHSADSSRQSGT----RHAETSSRGQTASSHEQARSSPGER 383
+ DG + PR + R + A R G+ R +++ + S P R
Sbjct: 394 RRGDGRKKPRWQNPRRRAQKAPAAKPRGGGSKKPRRRGPKAAKSRGGKSRSGGGKKPRRR 453
Query: 384 HGSGHQQSADSSRHSATGRGQASSAVSDRGHRGSSGSQASDS--------EGHSENSDTQ 435
Q++A++ S + Q S G + G S S + +
Sbjct: 454 GQKARQKAAEAGAESRGDKKQGRQKASAAGTKSRGGGLKSHSGKNLWRRGQKAEAAGEKA 513
Query: 436 SVSGHGKAGLRQQSHQESTRGRSGERSGRSGSSLYQVSTHEQPDSAHGRTGTSTGGRQGS 495
+ +G G +Q Q+ + R G S S Q + S G + G G+
Sbjct: 514 TAAGAKSRGRKQPRRQKPAVAGAKSRVGGSKSRQRQKAVAAGATSHGGGGNKQSRGGGGN 573
Query: 496 HHEQARDSSRHSASQEGQDTIRGHPGSSRG---GRQGSHHEQSVNR--SGHSGSHHSHTT 550
Q ++ + ++ G D G ++ G R G +++ + +G
Sbjct: 574 KPRQWGQTAAAAKTRGGGDKQPGWQKAAAGVTKSRSGDGGKKAWRQKAAGTGAKSRKKPW 633
Query: 551 SQGRSDA-------SHGQSGSRSASRQTRNEEQSGDGTRHSGS-------------RHHE 590
+G+ DA + G + S +Q R ++ + G+ S + R
Sbjct: 634 RRGQKDAAAAEKAWATGATSRGSGGKQPRWQKPAAAGSESSAAAAVGQEAEARKKPRRRR 693
Query: 591 ASSQADSSRHSQVG------------QGQSSGPRTSRNQGSSVSQDSDSQGHSEDSERWS 638
A S+ D +++ VG G+S G ++++GS ++ S G S +
Sbjct: 694 AKSRGDGGQNAAVGINPWQRRGKKPRLGKSRGGGGAKSRGSGGAKSRGSGGAKSRSGK-K 752
Query: 639 GSASRNHHGSAQEQSRDGSRHPRSHHED-RAGHGHSADSSRKSGTRHTQNSSSGQAASS 696
+AS++H G ++ R G RS + AG +A + K R GQ A++
Sbjct: 753 AAASKSHGGGGAKRRRGGGAKSRSGEKAVTAGGQKAAAAGGKKPPRVKSRGGRGQKAAA 811
Score = 57.0 bits (136), Expect = 4e-07
Identities = 99/527 (18%), Positives = 185/527 (35%), Gaps = 78/527 (14%)
Query: 3473 SDASRGQSGSRSASRQTRNDEQSGDGSRHSWSHHHEASTQADSSRHSQSGQGQSAGPRTS 3532
S A+ G S ++ R + + G + A ++ +H Q G AG +
Sbjct: 43 SAAAAGVKILGSGDKKLRRQKAAAGGKKARLRGQKGAVAGKEARQHWQKAAG--AGGAEN 100
Query: 3533 RNQGSSVSQDSDSQGHSEDSERWSGSASRNHRGSAQEQSRDGSRHPTSHHEDRAGHGHSA 3592
R G + + ++ G R R Q+ + GS+ P + A G
Sbjct: 101 RGGGEQKAAAAGTKS--------LGGRGRKPRRRGQKAAATGSKKPRWRAQKSAAAG--- 149
Query: 3593 ESSRQSGTHHAENSSGGQAASSHEQARSSAGERHGSHHQQSADSSRHSGIGHGQASSAVR 3652
S+ G +G Q A++ +S GE+ Q++A + G S + +
Sbjct: 150 --SKNRG-------AGAQKAAAAAGVKSQGGEKP----QKAAAA--------GAKSRSGK 188
Query: 3653 DSGHRGSSGSQASDSEGHSEDSDTQSVSAHGQAGPHQQSHQESTRGRSAGRSGRSGSFLY 3712
RG+ D +G ++ ++ G ++ H+ +S R G
Sbjct: 189 KPRRRGAKSRGDEDKKGRQREAKSRFGKTRGG---RRKKHRRPKPAAGGAKSRRGGGKKP 245
Query: 3713 QVSTHEQSESAHG---RAGPSTGGRQGSRHEQARDSSRHSASQEGQDTIRGHPGSR-RGG 3768
Q ++A G R G S GG Q ++++ A + G T P ++ RGG
Sbjct: 246 QKQRRRGQKAATGGKSRVGKSRGGGDKKLRRQGQNAALAGAKRRGAATAGEKPAAKGRGG 305
Query: 3769 RQGSYHEQSVDRSGHSGSHHSHTTSQGRSDASHGQSGSRSASRETRNEEQSGDGSRHSGS 3828
R S G + G+ G + R + + + G++ G
Sbjct: 306 R--------------------GPKSLGGQNPRWGRGGKKPRRRGQKATKAAAAGTKRGGG 345
Query: 3829 RHHEASTQADSSRHSQSGQGESAGSRRSRRQGSSVSQDSDSEAYPEDSERRSESASRNHH 3888
+A+ SR Q +G+ +++ G+ D + E ++RR + +
Sbjct: 346 GQQKAAVVGVKSRKKQRRRGKKPRRQKASAAGAKSRGGGDKKGLRE-AKRRGDGRKKPRW 404
Query: 3889 GSSREQSR---------DGSRHPGSSHRDTASHVQSSPVQSDSSTAKEHGHFSSLSQDSA 3939
+ R +++ GS+ P R +S +S S K+ ++ A
Sbjct: 405 QNPRRRAQKAPAAKPRGGGSKKP---RRRGPKAAKSRGGKSRSGGGKKPRRRGQKARQKA 461
Query: 3940 YHSGIQSRGSP----HSSSSYHYQSEGTERQKGQSGLVWRHGSYGSA 3982
+G +SRG +S+ +S G + +WR G A
Sbjct: 462 AEAGAESRGDKKQGRQKASAAGTKSRGGGLKSHSGKNLWRRGQKAEA 508
Score = 50.4 bits (119), Expect = 3e-05
Identities = 118/691 (17%), Positives = 242/691 (35%), Gaps = 112/691 (16%)
Query: 3277 RHAETSSGGQAASSHEQARSSPGERHGSRHQQSADSSRHSGIPRGQASSAVRDSRHWGSS 3336
R + ++GG+ A Q + G+ Q++A + G+ +A ++
Sbjct: 60 RRQKAAAGGKKARLRGQKGAVAGKEARQHWQKAAGAGGAENRGGGEQKAA--------AA 111
Query: 3337 GSQASDSEGHSEESDTQSVSGHGQAGPHQQSHQESARDRSGGRSGRSGSFLYQVSTHEQS 3396
G+++ G Q + G P ++ + +A +G ++ +G+ Q +
Sbjct: 112 GTKSLGGRGRKPRRRGQKAAATGSKKPRWRAQKSAA---AGSKNRGAGA---QKAAAAAG 165
Query: 3397 ESAHGRTRTSTGRRQGSHHEQARDSSRHSASQEGQDTIRGHP--GSSRRGRQGSHYEQSV 3454
+ G + G+ + R A G + +G SR G+
Sbjct: 166 VKSQGGEKPQKAAAAGAKSRSGKKPRRRGAKSRGDEDKKGRQREAKSRFGKT-------- 217
Query: 3455 DRSGHSGSHHSHTTSQGRSDASRGQSGSRSASRQTRNDEQSGDGSRHSWSHHHEASTQAD 3514
R G H + G + + RG G + +Q R +++ G +
Sbjct: 218 -RGGRRKKHRRPKPAAGGAKSRRG--GGKKPQKQRRRGQKAATGGK-------------- 260
Query: 3515 SSRHSQSGQGQSAGPRTSRNQGSSVSQDSDSQGHSEDSERWSGSASRNHRGSAQEQSRDG 3574
S+ G+ + G + R QG + + + G+A+ + +A+ + G
Sbjct: 261 ----SRVGKSRGGGDKKLRRQGQNAALAGAKR---------RGAATAGEKPAAKGR---G 304
Query: 3575 SRHPTSHHEDRAGHGHSAESSRQSGTHHAENSSGG-QAASSHEQARSSAGERHGSHHQQS 3633
R P S G + R+ G + ++ G + +Q + G + ++
Sbjct: 305 GRGPKSLGGQNPRWGRGGKKPRRRGQKATKAAAAGTKRGGGGQQKAAVVGVKSRKKQRRR 364
Query: 3634 ADSSRHSGIGHGQASSAVRDSGHRGSSGSQASDSEGHSEDSDTQSVSAHGQAGPHQQSHQ 3693
R +AS+A G+ D +G E G+ P Q+ +
Sbjct: 365 GKKPRRQ-----KASAA-------GAKSRGGGDKKGLREAKRR----GDGRKKPRWQNPR 408
Query: 3694 ESTRGRSAGRSGRSGSFLYQVSTHEQSESAHGRAGPSTGGRQ----GSRHEQARDSSRHS 3749
+ A + GS ++ +A S GG+ G + + +R
Sbjct: 409 RRAQKAPAAKPRGGGS--------KKPRRRGPKAAKSRGGKSRSGGGKKPRRRGQKARQK 460
Query: 3750 ASQEGQDTIRGHPGSRRGGRQGSYHEQSVDRSGHSGSHHSHTTSQGRSDASHGQSGSRSA 3809
A++ G ++ G ++ GRQ + + R G SH + A + +A
Sbjct: 461 AAEAGAES----RGDKKQGRQKASAAGTKSRGGGLKSHSGKNLWRRGQKAEAAGEKATAA 516
Query: 3810 SRETRNEEQ--------SGDGSRHSG--SRHHEASTQADSSRHSQSGQGESAGSRRSR-R 3858
++R +Q +G SR G SR + + A ++ H G +S G ++ R
Sbjct: 517 GAKSRGRKQPRRQKPAVAGAKSRVGGSKSRQRQKAVAAGATSHGGGGNKQSRGGGGNKPR 576
Query: 3859 QGSSVSQDSDSEAYPEDSERRSESASRNHHGSSREQSRDGSRHPGSSHRDTASHVQSSPV 3918
Q + + + + ++A+ G ++ +S DG + + R A+ +
Sbjct: 577 QWGQTAAAAKTRGGGDKQPGWQKAAA----GVTKSRSGDGGK---KAWRQKAAGTGA--- 626
Query: 3919 QSDSSTAKEHGHFSSLSQDSAYHSGIQSRGS 3949
G + + + A+ +G SRGS
Sbjct: 627 -KSRKKPWRRGQKDAAAAEKAWATGATSRGS 656
>gi|50962882 G patch domain containing 8 [Homo sapiens]
Length = 1502
Score = 98.6 bits (244), Expect = 1e-19
Identities = 167/739 (22%), Positives = 262/739 (35%), Gaps = 95/739 (12%)
Query: 959 SERWSGSASRNHRGSAQEQSRHGSRHPRSHHEDRAGHGHSADSSRQSGTPHAETSSGGQA 1018
SE+ G + H +A E + S P+S + A G S S P + +
Sbjct: 417 SEQMDGD-NTTHPKNAPESKKGSSPKPKSCIKAAASQGAEKTVSEVSEQPKETSMTEPSE 475
Query: 1019 ASSHEQARSSPGERHGSRHQQSADSSRHSGIPRRQASSAVRDSGHWGSSGSQASDSEGHS 1078
S +A+ + G G QS +S + S +S + S +
Sbjct: 476 PGSKAEAKKALG---GDVSDQSLESHSQKVSETQMCES---------NSSKETSLATPAG 523
Query: 1079 EESDTQSVSGHGQDGPHQQSHQESARDW------------SGGRSGRSGSFIYQVSTHEQ 1126
+ES G P + +A W S S F +++S ++
Sbjct: 524 KESQEGPKHPTGPFFPVLSKDESTALQWPSELLIFTKAEPSISYSCNPLYFDFKLSRNKD 583
Query: 1127 SESAHGRTRTSTGRRQGSHHEQARDSSRHSASQEGQDTIRAHPGSRRGGRQGSHHEQSVD 1186
+ + G H + + + + G + I G R ++
Sbjct: 584 ARTKGTEKPKDIGSSSKDHLQGLDPGEPNKSKEVGGEKIVRSSGGRMDAPASGSACSGLN 643
Query: 1187 RSGHSGSHHSHTTSQGRSDASHGQSGSRSASRQTRKDKQSGDGSRHSGSRHHEAASWADS 1246
+ GSH S T GRS S + +S + +K K+ S+H R H+A + S
Sbjct: 644 KQEPGGSHGSETEDTGRSLPSKKERSGKS--HRHKKKKKHKKSSKHK--RKHKADTEEKS 699
Query: 1247 SRHSQVGQEQSSGSRTSRHQGSSVSQDSDSERHSDDSERLSGSASRNHHGSSREQSRDGS 1306
S+ ++ G++ + R + S S +DSER SGS + R +++D S
Sbjct: 700 SK-AESGEKSKKRKKRKRKKNKS-SAPADSERGPKPEPPGSGSPAPPRR---RRRAQDDS 754
Query: 1307 RHPGFHQEDRASHGHSADSSRQSGTHHTESSSHGQAVSSHEQARSSPGERHGSRHQQSAD 1366
+ E+ +S + G + S HG R GE S Q+ A
Sbjct: 755 QRRSLPAEEGSS------GKKDEGGGGSSSQDHG--------GRKHKGELPPSSCQRRAG 800
Query: 1367 SSRHSGIGHR-QASSAVRDSGHRGS------SGSQVTNSEGHSEDSDTQSVSAHGQAGPH 1419
+ R S HR Q SS DS S S SQ + E EDS ++ + ++G
Sbjct: 801 TKRSSRSSHRSQPSSGDEDSDDASSHRLHQKSPSQYSEEE-EEEDSGSEHSRSRSRSGRR 859
Query: 1420 QQSHKESARGQSGESSGRSRSFLY--QVSSHEQSESTHGQTAPSTGGRQGSRHEQARNSS 1477
SH+ S R S S S Y Q S + S S + + R + SS
Sbjct: 860 HSSHRSSRRSYSSSSDASSDQSCYSRQRSYSDDSYSDYSDRSRRHSKRSHDSDDSDYASS 919
Query: 1478 RHSA------SQDGQDTIRGHPGSSRGGRQGSYHEQSVDRSGHSGYHHSHTTPQGRSDAS 1531
+H + S D ++ SR +S RS S S + + RS +
Sbjct: 920 KHRSKRHKYSSSDDDYSLSCSQSRSRSRSHTRERSRSRGRSRSSSCSRSRSKRRSRSTTA 979
Query: 1532 HG----QSGPRSASRQTRNEEQSGDG-----------SRHSGSRHHEPST--RAGSSRHS 1574
H +S R SR TR+ Q RHSG R S R+ S +
Sbjct: 980 HSWQRSRSYSRDRSRSTRSPSQRSGSRKRSWGHESPEERHSGRRDFIRSKIYRSQSPHYF 1039
Query: 1575 QVGQGESAGSKTSRR-----------QGSSVSQDRDSEGHSEDSERRSESASRNHYGSAR 1623
+ G+GE G K R Q S++ R SEG ++ S +A +
Sbjct: 1040 RSGRGEGPGKKDDGRGDDSKATGPPSQNSNIGTGRGSEGDCSPEDKNSVTAK---LLLEK 1096
Query: 1624 EQSRHGSRNPRSHQEDRAS 1642
QSR R P +E +A+
Sbjct: 1097 IQSRKVERKPSVSEEVQAT 1115
Score = 95.1 bits (235), Expect = 1e-18
Identities = 230/1054 (21%), Positives = 351/1054 (33%), Gaps = 163/1054 (15%)
Query: 1148 QARDSSRHSASQEGQDTIRAHPGSRRGGRQGSHHEQSVDRSGHSGSHHSHTTSQGRSDAS 1207
Q + + S++ ++T P S G + + D S S HS S+ + S
Sbjct: 452 QGAEKTVSEVSEQPKETSMTEP-SEPGSKAEAKKALGGDVSDQSLESHSQKVSETQMCES 510
Query: 1208 HGQSGSRSASRQTRKDKQSGDGSRHS--------GSRHHEAASWADSSRHSQVGQEQSSG 1259
+ S+ S T K+S +G +H A W + S
Sbjct: 511 NS---SKETSLATPAGKESQEGPKHPTGPFFPVLSKDESTALQWPSELLIFTKAEPSISY 567
Query: 1260 SRTSRHQGSSVSQDSDSERHSDDSERLSGSASRNHHGSSREQSRDGSRHPGFHQEDRASH 1319
S + +S++ D+ + + GS+S++H + S+ G + R+S
Sbjct: 568 SCNPLYFDFKLSRNKDARTKGTEKPKDIGSSSKDHLQGLDPGEPNKSKEVGGEKIVRSSG 627
Query: 1320 GHS---ADSSRQSGTHHTE-SSSHGQAVSSHEQARSSPGERHGSRHQQSADSSRHSGIGH 1375
G A S SG + E SHG ++ S ER G H+ H
Sbjct: 628 GRMDAPASGSACSGLNKQEPGGSHGSETEDTGRSLPSKKERSGKSHRHKKKKKHKKSSKH 687
Query: 1376 RQASSA-VRDSGHRGSSGSQVTNSEGHSEDSDTQSVSAHGQAGPHQQSHKESARGQSGES 1434
++ A + + SG + + + S A + GP K G +
Sbjct: 688 KRKHKADTEEKSSKAESGEKSKKRKKRKRKKNKSSAPADSERGP-----KPEPPGSGSPA 742
Query: 1435 SGRSRSFLYQVSSHEQSESTHGQTAPSTGGRQGSRHEQARNSSRHSASQDGQDTIRGHPG 1494
R R + + ++ P+ G G + E SS S G+ P
Sbjct: 743 PPRRR--------RRAQDDSQRRSLPAEEGSSGKKDEGGGGSS--SQDHGGRKHKGELPP 792
Query: 1495 SSRGGRQGSYHEQSVDRSGHSGYHHSHTTPQGRSDASHGQSGPRSASRQTRNEEQSGDGS 1554
SS R G+ RS H S + DAS + +S S+ + EE+ GS
Sbjct: 793 SSCQRRAGTKRSS---RSSHRSQPSSGD--EDSDDASSHRLHQKSPSQYSEEEEEEDSGS 847
Query: 1555 RHSGSRHHEPSTRAGSSRHSQVGQGESAGSKTSRRQGSSVSQDRDSEGHSEDSERRSESA 1614
HS SR +R+G RHS S S R+ S S D S+ + R S
Sbjct: 848 EHSRSR-----SRSGR-RHS---------SHRSSRRSYSSSSDASSD---QSCYSRQRSY 889
Query: 1615 SRNHYGSAREQSRHGSRNPRSHQEDRASHGHSAESSRQSGTRHAETSSGG--QAASSQEQ 1672
S + Y ++SR S+ RSH D + + SS+ RH +SS + SQ +
Sbjct: 890 SDDSYSDYSDRSRRHSK--RSHDSDDSDYA----SSKHRSKRHKYSSSDDDYSLSCSQSR 943
Query: 1673 ARSSPGERHGSRHQ-QSADSSTDSGTGRRQDSSVVGDSGNRGSSGSQASDSEGHSEESDT 1731
+RS R SR + +S SS +R+ S S R S
Sbjct: 944 SRSRSHTRERSRSRGRSRSSSCSRSRSKRRSRSTTAHSWQRSRS---------------- 987
Query: 1732 QSVSAHGQAGPHQQSHQESTRGQSGERSGRSGSFLYQVSTHEQSESAHGRTGPSTGGRQR 1791
+ + STR S R S+ HE E H +G R
Sbjct: 988 -----------YSRDRSRSTRSPSQRSGSRKRSW-----GHESPEERH------SGRRDF 1025
Query: 1792 SRHEQARDSSRHSASQEGQDTIRGHPGSSRGGRQGSHYEQSVDSSGHSG--SHHSHTTSQ 1849
R + R S H + S RG G + D S +G S +S+ +
Sbjct: 1026 IRSKIYRSQSPH------------YFRSGRGEGPGKKDDGRGDDSKATGPPSQNSNIGTG 1073
Query: 1850 ERSDVSRGQSGSRSVSRQTRNEK-QSGDGSRH-SGSRHHEASSRADSSRHSQVGQGQSSG 1907
S+ SV+ + EK QS R S S +A+ + QG G
Sbjct: 1074 RGSEGDCSPEDKNSVTAKLLLEKIQSRKVERKPSVSEEVQATPNKAGPKLKDPPQGY-FG 1132
Query: 1908 PRTSRNQGSSVSQDSDSQGHSEDSERWSGSASRNHLGSAWEQSRDGSRHPGSHHEDRAGH 1967
P+ + G+ + + S G EQS PGS A
Sbjct: 1133 PKLPPSLGNKPVLPLIGKLPATRKPNKKCEESGLERGEEQEQSETEEGPPGS---SDALF 1189
Query: 1968 GHSADSSRQSG---TRHTESSSRGQAASSHEQARSSA--------GERHGSHH------- 2009
GH S +G E S G+A + H A G+ SH+
Sbjct: 1190 GHQFPSEETTGPLLDPPPEESKSGEATADHPVAPLGTPAHSDCYPGDPTISHNYLPDPSD 1249
Query: 2010 --QLQSADSSRHSGIGHGQASSAVRDSGH----RGYSGSQASDSEGHSEDSDTQSVSAQG 2063
L+S DSS G D H SG + +S +ED+ + +Q
Sbjct: 1250 GDTLESLDSSSQPGPVESSLLPIAPDLEHFPSYAPPSGDPSIESTDGAEDASLAPLESQP 1309
Query: 2064 KAGPHQQSHKESARGQSGESSGRSGSFLYQVSTHEQSESTHGQSAPSTGGRQGSHYDQAQ 2123
++ K S Q+ + + QV S + AP+T Q H Q
Sbjct: 1310 ITFTPEEMEKYSKLQQAAQQHIQQQLLAKQVKAFPASAAL----APATPALQPIHIQQPA 1365
Query: 2124 DSS-------------RHSASQEGQDTIRGHPGP 2144
+S H+A+ I HP P
Sbjct: 1366 TASATSITTVQHAILQHHAAAAAAAIGIHPHPHP 1399
Score = 94.7 bits (234), Expect = 2e-18
Identities = 177/779 (22%), Positives = 286/779 (36%), Gaps = 94/779 (12%)
Query: 3167 NEEQSGDSSRHSVSRHHEASTHADISRHSQAVQGQSEGSRRSRRQGSSVSQDSDSEGHSE 3226
+E+ GD++ H ++ S + ++ + S+ + + S VS+ +E
Sbjct: 417 SEQMDGDNTTHP--KNAPESKKGSSPKPKSCIKAAA--SQGAEKTVSEVSEQPKETSMTE 472
Query: 3227 DSERWS-GSASRNHRGSVQEQSRHGSRHPRSHHEDRAGHGHS---------ADRSRQSGT 3276
SE S A + G V +QS H + E + +S A + Q G
Sbjct: 473 PSEPGSKAEAKKALGGDVSDQSLES--HSQKVSETQMCESNSSKETSLATPAGKESQEGP 530
Query: 3277 RHAETSSGGQAASSHEQARSSPGERHGSRHQQSADSSRHSGIPRGQASSAVRDSRHWGSS 3336
+H + A P E + + S + + S +D+R +
Sbjct: 531 KHPTGPFFPVLSKDESTALQWPSELLIFTKAEPSISYSCNPLYFDFKLSRNKDAR---TK 587
Query: 3337 GSQASDSEGHSEESDTQSVSGHGQAGPHQQSHQESARDRSGGR--SGRSGSFLYQVSTHE 3394
G++ G S + Q + G+ ++ E SGGR + SGS ++ E
Sbjct: 588 GTEKPKDIGSSSKDHLQGLDP-GEPNKSKEVGGEKIVRSSGGRMDAPASGSACSGLNKQE 646
Query: 3395 QSESAHGRTRTSTGRRQGSHHEQARDSSRHSASQEGQDTIRGHPGSSRRGRQGSHYEQSV 3454
S HG TGR S E++ S RH ++ H SS+ R+
Sbjct: 647 PGGS-HGSETEDTGRSLPSKKERSGKSHRHKKKKK-------HKKSSKHKRK-----HKA 693
Query: 3455 DRSGHSGSHHSHTTSQGRSDASRGQSGSRSASRQTRNDEQSGDGSRHSWSHHHEASTQAD 3514
D S S S+ R R ++ S + + R + GS Q D
Sbjct: 694 DTEEKSSKAESGEKSKKRKKRKRKKNKSSAPADSERGPKPEPPGSGSPAPPRRRRRAQDD 753
Query: 3515 SSRHSQSGQGQSAGPRTSRNQGSSVSQDSDSQGHSEDSERWSGSASRNHRGSAQEQSRDG 3574
S R S + S+G + GSS SQD + H + +S R + SR
Sbjct: 754 SQRRSLPAEEGSSGKKDEGGGGSS-SQDHGGRKHKGELP----PSSCQRRAGTKRSSRSS 808
Query: 3575 SRHPTSHHEDRAGHGHSAESSRQSGTHHAENSSGGQAASSHEQARSSAGERHGSHHQQSA 3634
R S ++ + S ++S + ++E + S H ++RS +G RH SH
Sbjct: 809 HRSQPSSGDEDSDDASSHRLHQKSPSQYSEEEEEEDSGSEHSRSRSRSGRRHSSHR---- 864
Query: 3635 DSSRHSGIGHGQASSAVRDSGHRGSSGSQASDSEGHSEDSDTQSVSAHGQAGPHQQSHQE 3694
SSR S + +S A D S + DS +S+ SD ++ H + +
Sbjct: 865 -SSRRS---YSSSSDASSDQSCYSRQRSYSDDS--YSDYSD--------RSRRHSKRSHD 910
Query: 3695 STRGRSAGRSGRSGSFLYQVSTHEQSES-AHGRAGPSTGGRQGSRHEQARDSSRHSASQE 3753
S A RS Y S + S S + R+ + R+ SR +R SR S+
Sbjct: 911 SDDSDYASSKHRSKRHKYSSSDDDYSLSCSQSRSRSRSHTRERSR---SRGRSRSSSCSR 967
Query: 3754 GQDTIRGHPGSRRGGRQGSYHEQSVDRSGHSGSHHSHTTSQGRSDASHGQ-SGSRSASRE 3812
+ S+R R + H R S++ + RS S Q SGSR S
Sbjct: 968 SR--------SKRRSRSTTAHSWQRSR--------SYSRDRSRSTRSPSQRSGSRKRSWG 1011
Query: 3813 TRNEEQSGDGSRHSGSRHHEAST--QADSSRHSQSGQGESAGSRRSRRQGSSVSQDSDSE 3870
+ E+ RHSG R S ++ S + +SG+GE G + R S + S+
Sbjct: 1012 HESPEE-----RHSGRRDFIRSKIYRSQSPHYFRSGRGEGPGKKDDGRGDDSKATGPPSQ 1066
Query: 3871 AYPEDSERRSESASRNHHGSS--------REQSRDGSRHPGSSHRDTASHVQSSPVQSD 3921
+ R SE +S + QSR R P S A+ ++ P D
Sbjct: 1067 NSNIGTGRGSEGDCSPEDKNSVTAKLLLEKIQSRKVERKPSVSEEVQATPNKAGPKLKD 1125
Score = 94.4 bits (233), Expect = 2e-18
Identities = 159/725 (21%), Positives = 261/725 (36%), Gaps = 93/725 (12%)
Query: 3244 QEQSRHGSRHPRSHHEDRAGHGHSADRS-RQSGTRHAETSSGGQAASSHEQARSSPGERH 3302
++ + HP++ E + G + + ++ AE + + E + + P E
Sbjct: 418 EQMDGDNTTHPKNAPESKKGSSPKPKSCIKAAASQGAEKTVSEVSEQPKETSMTEPSEP- 476
Query: 3303 GSRHQQSADSSRHSGIPRGQASSAVRDSRHWGSSGSQASDSEGHSEESDTQSVSGHGQAG 3362
GS+ A++ + G G S +S S +Q +S E S Q G
Sbjct: 477 GSK----AEAKKALG---GDVSDQSLESHSQKVSETQMCESNSSKETSLATPAGKESQEG 529
Query: 3363 PHQQS---HQESARDRSGGRSGRSGSFLYQVSTHEQSESAHGR------TRTSTGRRQGS 3413
P + ++D S S ++ + S S + +R R +G+
Sbjct: 530 PKHPTGPFFPVLSKDESTALQWPSELLIFTKAEPSISYSCNPLYFDFKLSRNKDARTKGT 589
Query: 3414 H-----------HEQARDSSRHSASQE--GQDTIRGHPGSSRRGRQGSHYEQSVDRSGHS 3460
H Q D + S+E G+ +R G GS +++
Sbjct: 590 EKPKDIGSSSKDHLQGLDPGEPNKSKEVGGEKIVRSSGGRMDAPASGSACS-GLNKQEPG 648
Query: 3461 GSHHSHTTSQGRSDASRGQSGSRSASRQTRNDEQSGDGSRHSWSHHHEASTQADSSRHSQ 3520
GSH S T GRS S+ + +S + + + S+H H+A T+ SS+
Sbjct: 649 GSHGSETEDTGRSLPSKKERSGKSHRHKKKKKHKKS--SKHK--RKHKADTEEKSSKAES 704
Query: 3521 SGQGQSAGPRTSRNQGSSVSQDSDSQGHSEDSERWSGSASRNHRGSAQEQSRDGSRHPTS 3580
+ + R + SS DS+ RG E GS P
Sbjct: 705 GEKSKKRKKRKRKKNKSSAPADSE-------------------RGPKPEPPGSGSPAPPR 745
Query: 3581 HHEDRAGHGHSAESSRQSGTHHAENSSGGQAASSHEQARSSAGERHGSHHQQSADSSRHS 3640
+ G+ ++ GG ++S R GE S Q+ A + R S
Sbjct: 746 RRRRAQDDSQRRSLPAEEGSSGKKDEGGGGSSSQDHGGRKHKGELPPSSCQRRAGTKRSS 805
Query: 3641 GIGH-GQASSAVRDSGHRGS------SGSQASDSEGHSEDSDTQSVSAHGQAGPHQQSHQ 3693
H Q SS DS S S SQ S+ E EDS ++ + ++G SH+
Sbjct: 806 RSSHRSQPSSGDEDSDDASSHRLHQKSPSQYSEEE-EEEDSGSEHSRSRSRSGRRHSSHR 864
Query: 3694 ESTRGRSAGRSGRSGSFLYQVSTHEQSESAHGRAGPSTGGRQGSRHEQARDSSRHSASQE 3753
S R S+ S Y + ++S S + S R+ S+ D S +++S+
Sbjct: 865 SSRRSYSSSSDASSDQSCY---SRQRSYSDDSYSDYSDRSRRHSKRSHDSDDSDYASSKH 921
Query: 3754 GQDTIRGHPGSRRGGRQGSYHEQSVDRSGHSGSHHSHTTSQGRSDASHGQSGSRSASRET 3813
S+R S + S+ S SHT + R S G+S S S SR +
Sbjct: 922 R---------SKRHKYSSSDDDYSLSCSQSRSRSRSHTRERSR---SRGRSRSSSCSR-S 968
Query: 3814 RNEEQSGDGSRHSGSRHHEASTQADSSRHSQSGQGESAGSRRSRRQGSSVSQDSDSEAYP 3873
R++ +S + HS R S D SR ++S S +RS S + S +
Sbjct: 969 RSKRRSRSTTAHSWQR--SRSYSRDRSRSTRSPSQRSGSRKRSWGHESPEERHSGRRDFI 1026
Query: 3874 EDSERRSES-----ASRNHHGSSREQSR-DGSRHPGSSHRDT------ASHVQSSPVQSD 3921
RS+S + R ++ R D S+ G +++ S SP +
Sbjct: 1027 RSKIYRSQSPHYFRSGRGEGPGKKDDGRGDDSKATGPPSQNSNIGTGRGSEGDCSPEDKN 1086
Query: 3922 SSTAK 3926
S TAK
Sbjct: 1087 SVTAK 1091
Score = 94.0 bits (232), Expect = 3e-18
Identities = 109/499 (21%), Positives = 177/499 (35%), Gaps = 41/499 (8%)
Query: 2821 SQGRSDASRGQSGSRSASRTTRNEEQSGDGSRHSGSRH--HEASTHADISRHSQAVQGQS 2878
S+ + ++G + ++++ Q D + S+ E + R G +
Sbjct: 579 SRNKDARTKGTEKPKDIGSSSKDHLQGLDPGEPNKSKEVGGEKIVRSSGGRMDAPASGSA 638
Query: 2879 EGSRRSRRQGSSVSQDSDSEGHSEDSERWSGSASRNHHGSAQEQLRDGSRHPRSHQEDRA 2938
+ G S +++ G S S++ S H +++ + S+H R H+ D
Sbjct: 639 CSGLNKQEPGGSHGSETEDTGRSLPSKKERSGKSHRH--KKKKKHKKSSKHKRKHKADTE 696
Query: 2939 GHGHSADSSRQSGTRHTQTSSGGQAASSHEQARSSAGERHGS-------HHQQSADSSRH 2991
A+S +S R + ++++ + R E GS +++ D S+
Sbjct: 697 EKSSKAESGEKSKKRKKRKRKKNKSSAPADSERGPKPEPPGSGSPAPPRRRRRAQDDSQR 756
Query: 2992 SGIGHGQASSAVRDSGHRGYSGSQASDNEGHSEDSDTQSVSAHGQAG---SHQQSHQESA 3048
+ + SS +D G GS + D+ G + S +AG S + SH+
Sbjct: 757 RSLPAEEGSSGKKDEGG---GGSSSQDHGGRKHKGELPPSSCQRRAGTKRSSRSSHRSQP 813
Query: 3049 RGRSGETSGHSGSFLYQVS----THEQSESSHGWTGPSTRGRQGSRHEQAQDSSRHSAS- 3103
++ S L+Q S + E+ E G +R R G RH + S R +S
Sbjct: 814 SSGDEDSDDASSHRLHQKSPSQYSEEEEEEDSGSEHSRSRSRSGRRHSSHRSSRRSYSSS 873
Query: 3104 --------------QYGQDTIRGHPGSSRGGRQGYHHEHSVD--SSGHSGSHHSHTTSQG 3147
Y D+ + SR + H D SS H H +++S
Sbjct: 874 SDASSDQSCYSRQRSYSDDSYSDYSDRSRRHSKRSHDSDDSDYASSKHRSKRHKYSSSDD 933
Query: 3148 RSDASRGQSGSRSASRTTRNEEQSGDSSRHSVSRHHEASTHADISRHS-QAVQGQSEGSR 3206
S QS SRS S T G S S SR + HS Q + S
Sbjct: 934 DYSLSCSQSRSRSRSHTRERSRSRGRSRSSSCSRSRSKRRSRSTTAHSWQRSRSYSRDRS 993
Query: 3207 RSRRQGSSVS-QDSDSEGHSEDSERWSGSASRNHRGSVQEQSRHGSRHPRSHHEDRAGHG 3265
RS R S S S GH ER SG + QS H R R + G
Sbjct: 994 RSTRSPSQRSGSRKRSWGHESPEERHSGRRDFIRSKIYRSQSPHYFRSGRGEGPGKKDDG 1053
Query: 3266 HSADRSRQSGTRHAETSSG 3284
D S+ +G ++ G
Sbjct: 1054 R-GDDSKATGPPSQNSNIG 1071
Score = 92.8 bits (229), Expect = 6e-18
Identities = 123/500 (24%), Positives = 190/500 (38%), Gaps = 74/500 (14%)
Query: 2528 RHSGSRHHEASSRADSSGHSQVGQGQSEGPRTSRNWGSSFSQDSDSQGHSEDSERWSGSA 2587
R SG R +S + SG ++ G S G T + G S + G S
Sbjct: 624 RSSGGRMDAPASGSACSGLNKQEPGGSHGSETE-DTGRSLPSKKERSGKS---------- 672
Query: 2588 SRNHHGSAQEQLRDGSRHPRSHQEDRAGHGHSADSSRQSGTRHTQTSSGGQAASSHEQAR 2647
H +++ + S+H R H+ D A+S +S R + ++++ + R
Sbjct: 673 ---HRHKKKKKHKKSSKHKRKHKADTEEKSSKAESGEKSKKRKKRKRKKNKSSAPADSER 729
Query: 2648 SSAGERHGS-------HHQQSADSSRHSGIGHGQASSAVRDSGHRGYSGSQASDNEGHSE 2700
E GS +++ D S+ + + SS +D G GS + D+ G
Sbjct: 730 GPKPEPPGSGSPAPPRRRRRAQDDSQRRSLPAEEGSSGKKDEGG---GGSSSQDHGGRKH 786
Query: 2701 DSDTQSVSAHGQAGSHQQSHQESARGRSGETSGHSGSFLYQVSTHEQSESSHGWTGPSTR 2760
+ S +AG+ + S RS +SG S S+H + S PS
Sbjct: 787 KGELPPSSCQRRAGTKRSSRSSH---RSQPSSGDEDS--DDASSHRLHQKS-----PS-- 834
Query: 2761 GRQGSRHEQAQDS-SRHSASQDGQDTIRGHPGSSRGGRQGYHHEHSVDSSGHSGSHHSHT 2819
Q S E+ +DS S HS S+ SR GR+ H S S S S
Sbjct: 835 --QYSEEEEEEDSGSEHSRSR------------SRSGRRHSSHRSSRRSYSSSSDASSDQ 880
Query: 2820 TSQGRSDASRGQSGSRSASRTTRNEEQSGD-------GSRHSGSRHHEASTHADISRHSQ 2872
+ R + S S + R+ R+ ++S D S+H RH +S+ D S
Sbjct: 881 SCYSRQRSYSDDSYSDYSDRSRRHSKRSHDSDDSDYASSKHRSKRHKYSSSDDDYS--LS 938
Query: 2873 AVQGQSEGSRRSRRQGSSVSQDSDSEGHSEDSERWSGSASRNHHGSAQEQLRDGSRHPRS 2932
Q +S +R + S + S S+R S S + + ++ RD SR RS
Sbjct: 939 CSQSRSRSRSHTRERSRSRGRSRSSSCSRSRSKRRSRSTTAHSWQRSRSYSRDRSRSTRS 998
Query: 2933 HQEDRAGH-----GHSADSSRQSGTRHTQTSSGGQAASSHEQARSSAGERHGSHHQQSAD 2987
+ R+G GH + R SG R S ++ S H RS GE G D
Sbjct: 999 PSQ-RSGSRKRSWGHESPEERHSGRRDFIRSKIYRSQSPH-YFRSGRGEGPGKKDDGRGD 1056
Query: 2988 SSR-------HSGIGHGQAS 3000
S+ +S IG G+ S
Sbjct: 1057 DSKATGPPSQNSNIGTGRGS 1076
Score = 90.9 bits (224), Expect = 2e-17
Identities = 137/600 (22%), Positives = 213/600 (35%), Gaps = 94/600 (15%)
Query: 417 SSGSQASDSEGHSENSDTQSVSGHGKAGLRQQSHQESTRGRSGERSGRSGSSLYQVSTHE 476
+ G++ G S Q + ++ ++ R G + S +
Sbjct: 586 TKGTEKPKDIGSSSKDHLQGLDPGEPNKSKEVGGEKIVRSSGGRMDAPASGSACSGLNKQ 645
Query: 477 QPDSAHGRTGTSTGGRQGSHHEQARDSSRHSASQEGQDTIRGHPGSSRGGRQGSHHEQSV 536
+P +HG TG S E++ S RH ++ H SS+ R+ +
Sbjct: 646 EPGGSHGSETEDTGRSLPSKKERSGKSHRHKKKKK-------HKKSSKHKRKHKADTEEK 698
Query: 537 NRSGHSGSHHSHTTSQGRSDASHGQSGSRSASRQTRNEEQSGDGTRHSGSRHHEASSQAD 596
+ SG + R +S + + S + E G G+ R A Q D
Sbjct: 699 SSKAESGEKSKKRKKRKR---KKNKSSAPADSERGPKPEPPGSGSPAPPRRRRRA--QDD 753
Query: 597 SSRHSQVGQGQSSGPRTSRNQGSSVSQDSDSQGHSED-----------SERWSGSASRNH 645
S R S + SSG + GSS SQD + H + ++R S S+ R+
Sbjct: 754 SQRRSLPAEEGSSGKKDEGGGGSS-SQDHGGRKHKGELPPSSCQRRAGTKRSSRSSHRSQ 812
Query: 646 HGSAQEQSRDGSRHPRSHHEDRAGHGHSADSSRKSGTRHTQNSSSGQAASSHEQARSSAG 705
S E S D S H R H +KS +++++ + S H ++RS +G
Sbjct: 813 PSSGDEDSDDASSH-RLH--------------QKSPSQYSEEEEEEDSGSEHSRSRSRSG 857
Query: 706 ERHGSRHQLQSADSSRHSGTGHGQASSAVRDSGHRGSSGSQATDSEGHSEDSDTQSVSGH 765
RH S SSR S + ASS Q+ S S D+ S
Sbjct: 858 RRHSSHR------SSRRSYSSSSDASS------------DQSCYSRQRSYSDDSYSDYSD 899
Query: 766 GQAGHHQQSHQESARDRSGERSRRSGSFLYQVSTHKQSESSHGWTGPSTGVRQGSH-HEQ 824
H ++SH D + + R HK S S ++ + R S H +
Sbjct: 900 RSRRHSKRSHDSDDSDYASSKHRS--------KRHKYSSSDDDYSLSCSQSRSRSRSHTR 951
Query: 825 ARDNSRHSASQDGQDTIRGHPGSSRRGRQGSHHEQSVDRSGHSGSHHSHTTSQGRSDASR 884
R SR + R S RR R + H R S++ + RS S
Sbjct: 952 ERSRSRGRSRSSSCSRSR----SKRRSRSTTAHSWQRSR--------SYSRDRSRSTRSP 999
Query: 885 GQ-SGSRSASRTTRNEEQSRDGSRHSGSRHHEASS--HADISRHSQAGQGQSEGSRTSRR 941
Q SGSR S + E+ RHSG R S + + ++G+G+ G + R
Sbjct: 1000 SQRSGSRKRSWGHESPEE-----RHSGRRDFIRSKIYRSQSPHYFRSGRGEGPGKKDDGR 1054
Query: 942 QGSSVSQDSDSEGHSEDSERWS-GSASRNHRGSA-------QEQSRHGSRHPRSHHEDRA 993
S + S+ + + R S G S + S + QSR R P E +A
Sbjct: 1055 GDDSKATGPPSQNSNIGTGRGSEGDCSPEDKNSVTAKLLLEKIQSRKVERKPSVSEEVQA 1114
Score = 89.7 bits (221), Expect = 5e-17
Identities = 161/790 (20%), Positives = 279/790 (35%), Gaps = 114/790 (14%)
Query: 1830 EQSVDSSGHSGSHHSHTTSQERSDVSRGQSGSRSVSRQTRNEKQSGDGSRHSGSRHHEAS 1889
+Q + G S + +E D G S + ++S+ R +++ G G+ H+
Sbjct: 340 DQGLQKVGDSDGSSNLDGKKEDEDPQDGGSLASTLSKLKRMKREEGAGATEPEYYHYIPP 399
Query: 1890 SRADSSRHSQV-----GQGQSSGPRTSRNQGSSVSQDSDSQGHSEDSERWSGSASRNHLG 1944
+ + Q G T+ + + S+ S + + + +
Sbjct: 400 AHCKVKPNFPFLLFMRASEQMDGDNTTHPKNAPESKKGSSPKPKSCIKAAASQGAEKTVS 459
Query: 1945 SAWEQSRDGSR----HPGSHHEDRAGHGHSADSSRQSGTRHTESSSRGQAASSHEQARSS 2000
EQ ++ S PGS E + G D S QS H++ S Q S+ +S
Sbjct: 460 EVSEQPKETSMTEPSEPGSKAEAKKALG--GDVSDQSLESHSQKVSETQMCESNSSKETS 517
Query: 2001 A----------GERH--GSHHQLQSADSSR-----HSGIGHGQASSAVRDSGHRGYSGSQ 2043
G +H G + S D S + +A ++ S + Y +
Sbjct: 518 LATPAGKESQEGPKHPTGPFFPVLSKDESTALQWPSELLIFTKAEPSISYSCNPLYFDFK 577
Query: 2044 ASDSEGHSEDSDTQSVSAQGKAGPHQQSHKESAR-GQSGESSGRSGSFLYQVSTHEQSES 2102
S ++D+ T+ G + H + G+ +S G + + S
Sbjct: 578 LS----RNKDARTKGTEKPKDIGSSSKDHLQGLDPGEPNKSKEVGGEKIVRSSGGRMDAP 633
Query: 2103 THGQSAPSTGGRQ--GSHYDQAQDSSRHSASQEGQDTIRGHPGPSRGGRQGSHQEQSVDR 2160
G + ++ GSH + +D+ R S++ R G+ SH+ + +
Sbjct: 634 ASGSACSGLNKQEPGGSHGSETEDTGRSLPSKK-----------ERSGK--SHRHKKKKK 680
Query: 2161 SGHSGSHHSHTTSQGRSDASRGQSGSRSASRKTYDKEQS-----------------GDGS 2203
S H + +S+ +SG +S RK ++++ G GS
Sbjct: 681 HKKSSKHKRKHKADTEEKSSKAESGEKSKKRKKRKRKKNKSSAPADSERGPKPEPPGSGS 740
Query: 2204 RHSGSHHHEASSWADSSRHSLVGQGQSSGPRTSRPRGSSVSQDSDSEGHSED-------- 2255
A DS R SL + SSG + GSS SQD H +
Sbjct: 741 PAPPRRRRRAQD--DSQRRSLPAEEGSSGKKDEGGGGSS-SQDHGGRKHKGELPPSSCQR 797
Query: 2256 ---SERRSGSASRNHHGSAQEQSRDGSRHPRSHHEDRAGHGHSAESSRQSGTHHAENSSG 2312
++R S S+ R+ S E S D S H R H ++S + ++E
Sbjct: 798 RAGTKRSSRSSHRSQPSSGDEDSDDASSH-RLH--------------QKSPSQYSEEEEE 842
Query: 2313 GQAASSHEQARSSAGERHGSHHQQSADSSRHSGIGHGQASSAVRDSGHRGSSGSQASDSE 2372
+ S H ++RS +G RH SH S S Q+ + + S S + S
Sbjct: 843 EDSGSEHSRSRSRSGRRHSSHRSSRRSYSSSSDASSDQSCYSRQRSYSDDSYSDYSDRSR 902
Query: 2373 GHSEDSDTQSVSAHGQAGPHQQSHQESTRGRSAGRSGRSGSFLYQVSTHEQSESAHGRTG 2432
HS+ S S + + + H+ S+ S + T E+S S GR+
Sbjct: 903 RHSKRSHDSDDSDYASSKHRSKRHKYSSSDDDYSLSCSQSRSRSRSHTRERSRS-RGRSR 961
Query: 2433 TSTGGRQGSHHKQARDSSRHS-----TSQEGQDTIHGHPGSSSGGRQGSHYEQLVDRSGH 2487
+S+ R S +++R ++ HS + + P SG R+ S GH
Sbjct: 962 SSSCSRSRS-KRRSRSTTAHSWQRSRSYSRDRSRSTRSPSQRSGSRKRSW--------GH 1012
Query: 2488 SGSHHSHTTSQGRSDASHGHSGSRSASRQTRNDEQSGDGSRHSGSRHHEASSRADSSGHS 2547
H+ GR D + R+ G G + G R ++ + S +S
Sbjct: 1013 ESPEERHS---GRRDFIRSKIYRSQSPHYFRSGRGEGPGKKDDG-RGDDSKATGPPSQNS 1068
Query: 2548 QVGQGQ-SEG 2556
+G G+ SEG
Sbjct: 1069 NIGTGRGSEG 1078
Score = 89.7 bits (221), Expect = 5e-17
Identities = 123/484 (25%), Positives = 183/484 (37%), Gaps = 102/484 (21%)
Query: 294 GSRVSQDRDSEGHSEDSERHSGSASRNHHGSAWEQSRDGSRHPRSHDEDRASHGHSADSS 353
GS S+ D+ G S S++ S H ++ + S+H R H D A+S
Sbjct: 649 GSHGSETEDT-GRSLPSKKERSGKSHRHKKK--KKHKKSSKHKRKHKADTEEKSSKAESG 705
Query: 354 RQSGTRHAETSSRGQTASSHEQARSSPGERHGSG-------HQQSADSSRHSATGRGQAS 406
+S R + ++++ + R E GSG +++ D S+ + + S
Sbjct: 706 EKSKKRKKRKRKKNKSSAPADSERGPKPEPPGSGSPAPPRRRRRAQDDSQRRSLPAEEGS 765
Query: 407 SAVSDRGHRGSSGSQASDSEGHSENSDTQSVSGHGKAGLRQQSHQESTRGRSGERSGRSG 466
S D G GSS + D G + S +AG ++ S RS RS
Sbjct: 766 SGKKDEGGGGSS---SQDHGGRKHKGELPPSSCQRRAGTKRSS-------RSSHRS---- 811
Query: 467 SSLYQVSTHEQPDSAHGRTGTSTGGRQGSHHEQARDSSRHSASQEGQDTIRGHPGSSRGG 526
QP S G SH + S++S +E +D+
Sbjct: 812 ----------QPSS-----GDEDSDDASSHRLHQKSPSQYSEEEEEEDS----------- 845
Query: 527 RQGSHHEQSVNRSG--HSGSHHSHTTSQGRSDASHGQSGSRSASRQTRNEEQSGDGTRHS 584
GS H +S +RSG HS S + SDAS QS SRQ + S
Sbjct: 846 --GSEHSRSRSRSGRRHSSHRSSRRSYSSSSDASSDQS---CYSRQRSYSDDSYSDYSDR 900
Query: 585 GSRHHEASSQADSSRHSQVGQGQSSGPRTSRNQGSSVSQD---------SDSQGHSEDSE 635
RH + S +D S ++ SS R+ R++ SS D S S+ H+ +
Sbjct: 901 SRRHSKRSHDSDDSDYA------SSKHRSKRHKYSSSDDDYSLSCSQSRSRSRSHTRERS 954
Query: 636 RWSG-------SASRNHHGS----------AQEQSRDGSRHPRSHHEDRAGH-----GHS 673
R G S SR+ S ++ SRD SR RS + R+G GH
Sbjct: 955 RSRGRSRSSSCSRSRSKRRSRSTTAHSWQRSRSYSRDRSRSTRSPSQ-RSGSRKRSWGHE 1013
Query: 674 ADSSRKSGTRHTQNSSSGQAASSHEQARSSAGERHGSRHQLQSADS------SRHSGTGH 727
+ R SG R S ++ S H RS GE G + + DS S++S G
Sbjct: 1014 SPEERHSGRRDFIRSKIYRSQSPH-YFRSGRGEGPGKKDDGRGDDSKATGPPSQNSNIGT 1072
Query: 728 GQAS 731
G+ S
Sbjct: 1073 GRGS 1076
Score = 88.2 bits (217), Expect = 2e-16
Identities = 174/841 (20%), Positives = 283/841 (33%), Gaps = 113/841 (13%)
Query: 1592 SSVSQDRDSEGHSEDSERRSESASRNHYGSAREQSRHGSRNPRSHQEDRASHGHSAESSR 1651
+SV +D EG SED + E +S G + GS N +ED + +S
Sbjct: 316 ASVFKDHAEEGTSEDGTKPDEKSSDQ--GLQKVGDSDGSSNLDGKKEDEDPQDGGSLAST 373
Query: 1652 QSGTRHAETSSGGQAASSQEQARSSPGERHGSRH-------QQSADSSTDSGTGRRQDSS 1704
S + + G A + P + + S D+ T +
Sbjct: 374 LSKLKRMKREEGAGATEPEYYHYIPPAHCKVKPNFPFLLFMRASEQMDGDNTTHPKN--- 430
Query: 1705 VVGDSGNRGSSGSQASDSEGHSEESDTQSVSAHGQAGPHQQSHQESTRGQSGERSGRSGS 1764
+GSS S + + + ++VS + + S G E G
Sbjct: 431 --APESKKGSSPKPKSCIKAAASQGAEKTVSEVSEQPKETSMTEPSEPGSKAEAKKALGG 488
Query: 1765 FLYQVSTHEQSESAHGRTGPSTGG-RQRSRHEQARDSSRHSASQEGQDTIRG--HPGSSR 1821
+QS +H + T S E + + SQEG G P S+
Sbjct: 489 -----DVSDQSLESHSQKVSETQMCESNSSKETSLATPAGKESQEGPKHPTGPFFPVLSK 543
Query: 1822 GGRQGSHY----------EQSVDSSGHSGSHHSHTTSQERSDVSRGQSGSRSVSRQTRNE 1871
+ E S+ S + + S+ + ++G + + +++
Sbjct: 544 DESTALQWPSELLIFTKAEPSISYSCNP-LYFDFKLSRNKDARTKGTEKPKDIGSSSKDH 602
Query: 1872 KQSGDGSRHSGSRH--HEASSRADSSRHSQVGQGQSSGPRTSRNQGSSVSQDSDSQGHSE 1929
Q D + S+ E R+ R G + + G S +++ G S
Sbjct: 603 LQGLDPGEPNKSKEVGGEKIVRSSGGRMDAPASGSACSGLNKQEPGGSHGSETEDTGRSL 662
Query: 1930 DSERWSGSASRNHLGSAWEQSRDGSRHPGSHHEDRAGHGHSADSSRQSGTRHTESSSRGQ 1989
S++ S H ++ + S+H H D A+S +S R + +
Sbjct: 663 PSKKERSGKSHRHKKK--KKHKKSSKHKRKHKADTEEKSSKAESGEKSKKRKKRKRKKNK 720
Query: 1990 AASSHEQARSSAGERHGS------HHQLQSADSSRHSGIGHGQASSAVRDSGHRGYSGSQ 2043
+++ + R E GS + ++ D S+ + + SS +D G GS
Sbjct: 721 SSAPADSERGPKPEPPGSGSPAPPRRRRRAQDDSQRRSLPAEEGSSGKKDEGG---GGSS 777
Query: 2044 ASDSEGHSEDSDTQSVSAQGKAGPHQQS---HKESARGQSGESSGRSGSFLYQVSTHEQS 2100
+ D G + S Q +AG + S H+ +S S L+Q S + S
Sbjct: 778 SQDHGGRKHKGELPPSSCQRRAGTKRSSRSSHRSQPSSGDEDSDDASSHRLHQKSPSQYS 837
Query: 2101 E--------STHGQSAPSTGGRQGSHYDQAQDSSRHSASQEGQDTIRGHPGPSRGGRQGS 2152
E S H +S +G R SH + S S + Q RQ S
Sbjct: 838 EEEEEEDSGSEHSRSRSRSGRRHSSHRSSRRSYSSSSDASSDQSCY---------SRQRS 888
Query: 2153 HQEQSVDRSGHSGSHHSHTTSQGRSDASRGQSGSRSASRKTYDKEQSGDGSRHSGSH--- 2209
+ + S SD S SR S++++D S D S H
Sbjct: 889 YSDDSY------------------SDYS---DRSRRHSKRSHD---SDDSDYASSKHRSK 924
Query: 2210 HHEASSWADSSRHSLVGQGQSSGPRTSRPRGSSVSQDSDSEGHSEDSERRSGSASRNHHG 2269
H+ SS +D Q +S +R R S + S S+RRS S + +
Sbjct: 925 RHKYSS-SDDDYSLSCSQSRSRSRSHTRERSRSRGRSRSSSCSRSRSKRRSRSTTAHSWQ 983
Query: 2270 SAQEQSRDGSRHPRSHHEDRAGH-----GHSAESSRQSGTHHAENSSGGQAASSHEQARS 2324
++ SRD SR RS + R+G GH + R SG S ++ S H RS
Sbjct: 984 RSRSYSRDRSRSTRSPSQ-RSGSRKRSWGHESPEERHSGRRDFIRSKIYRSQSPH-YFRS 1041
Query: 2325 SAGERHGSHHQQSADSSRHSGIGHGQASSAVRDSGHRGSSGSQASDSEGHSEDSDTQSVS 2384
GE G D S+ +G + S+ SEG D SV+
Sbjct: 1042 GRGEGPGKKDDGRGDDSKATG------------PPSQNSNIGTGRGSEGDCSPEDKNSVT 1089
Query: 2385 A 2385
A
Sbjct: 1090 A 1090
Score = 86.3 bits (212), Expect = 6e-16
Identities = 118/475 (24%), Positives = 185/475 (38%), Gaps = 56/475 (11%)
Query: 819 GSHHEQARDNSRHSASQDGQDTIRGHPGSSRRGRQGSHHEQSVDRSGHSGSHHSHTTSQG 878
GSH + D R S+ + G S R ++ H++S S H H + T +
Sbjct: 649 GSHGSETEDTGRSLPSK------KERSGKSHRHKKKKKHKKS---SKHKRKHKADTEEK- 698
Query: 879 RSDASRGQSGSRSASRTTRNEEQSRDGSRHSGSRHHEASSHADIS----RHSQAGQGQSE 934
+S+ +SG +S R R ++++ + R + S R + Q S+
Sbjct: 699 ---SSKAESGEKSKKRKKRKRKKNKSSAPADSERGPKPEPPGSGSPAPPRRRRRAQDDSQ 755
Query: 935 GSRTSRRQGSSVSQDSDSEGHSEDSERWSGSASRNHRGSAQEQS---RHGS-RHPRSHHE 990
+GSS +D G S R H+G S R G+ R RS H
Sbjct: 756 RRSLPAEEGSSGKKDEGGGGSSSQDH-----GGRKHKGELPPSSCQRRAGTKRSSRSSHR 810
Query: 991 DRAGHGH--SADSS-----RQSGTPHAETSSGGQAASSHEQARSSPGERHGSRHQQSADS 1043
+ G S D+S ++S + ++E + S H ++RS G RH S H+ S S
Sbjct: 811 SQPSSGDEDSDDASSHRLHQKSPSQYSEEEEEEDSGSEHSRSRSRSGRRHSS-HRSSRRS 869
Query: 1044 SRHSGIPRRQASSAVRDSGHWGSSGSQASD-SEGHSEESDTQSVSGHGQDGPHQQSHQES 1102
S S R + S S SD S HS+ S S + + H+ S
Sbjct: 870 YSSSSDASSDQSCYSRQRSYSDDSYSDYSDRSRRHSKRSHDSDDSDYASSKHRSKRHKYS 929
Query: 1103 ARDWSGGRSGRSGSFIYQVSTHEQSESAHGRTRTSTGRRQGSHHEQARDSSRHS---ASQ 1159
+ D S + T E+S S GR+R+S+ R S ++R ++ HS +
Sbjct: 930 SSDDDYSLSCSQSRSRSRSHTRERSRS-RGRSRSSSCSRSRS-KRRSRSTTAHSWQRSRS 987
Query: 1160 EGQDTIRA--HPGSRRGGRQGS-HHEQSVDRSGHSGSHHSHTTSQGRSDASHGQSGSRSA 1216
+D R+ P R G R+ S HE +R HSG + RS + H R
Sbjct: 988 YSRDRSRSTRSPSQRSGSRKRSWGHESPEER--HSGRRDFIRSKIYRSQSPHYFRSGRGE 1045
Query: 1217 SRQTRKDKQSGDGSRHSGSRHHEAASWADSSRHSQVGQEQSSGSRTSRHQGSSVS 1271
+KD GD S+ +G S++S +G + S S +SV+
Sbjct: 1046 G-PGKKDDGRGDDSKATG----------PPSQNSNIGTGRGSEGDCSPEDKNSVT 1089
Score = 85.5 bits (210), Expect = 1e-15
Identities = 114/482 (23%), Positives = 166/482 (34%), Gaps = 81/482 (16%)
Query: 2231 SGPRTSRPRGSSVSQDSDSEGHSEDSERRSGSASRNHHGSAQEQSRDGSRHPRSHHEDRA 2290
SG P GS S+ D+ + RSG ++H +++ + S+H R H D
Sbjct: 640 SGLNKQEPGGSHGSETEDTGRSLPSKKERSG---KSHRHKKKKKHKKSSKHKRKHKADTE 696
Query: 2291 GHGHSAESSRQSGTHHAENSSGGQAASSHEQARSSAGERHGS-------HHQQSADSSRH 2343
AES +S ++++ + R E GS +++ D S+
Sbjct: 697 EKSSKAESGEKSKKRKKRKRKKNKSSAPADSERGPKPEPPGSGSPAPPRRRRRAQDDSQR 756
Query: 2344 SGIGHGQASSAVRDSGHRGSSGSQASDSEGHSEDSDTQSVSAHGQAGPHQQSHQESTRGR 2403
+ + SS +D G GSS + D G + S +AG + S
Sbjct: 757 RSLPAEEGSSGKKDEGGGGSS---SQDHGGRKHKGELPPSSCQRRAGTKRSSRSSHRSQP 813
Query: 2404 SAG---RSGRSGSFLYQVSTHEQSE--------SAHGRTGTSTGGRQGSHHKQARDSSRH 2452
S+G S L+Q S + SE S H R+ + +G R SH R S
Sbjct: 814 SSGDEDSDDASSHRLHQKSPSQYSEEEEEEDSGSEHSRSRSRSGRRHSSHRSSRRSYSSS 873
Query: 2453 STSQEGQDTIH--------GHPGSSSGGRQGSHYEQLVDRSGHSGSHHS---HTTSQGRS 2501
S + Q + S R+ S D S ++ S H H S
Sbjct: 874 SDASSDQSCYSRQRSYSDDSYSDYSDRSRRHSKRSHDSDDSDYASSKHRSKRHKYSSSDD 933
Query: 2502 DASHGHSGSRSASRQTRNDEQSGDGSRHSGSRHHEASSRADSSGHSQVGQGQSEGPRTSR 2561
D S S SRS SR + G S S S R S T+
Sbjct: 934 DYSLSCSQSRSRSRSHTRERSRSRGRSRSSSCSRSRSKRRSRS-------------TTAH 980
Query: 2562 NWGSSFSQDSDSQGHSEDSERWSGSASRNHHGSAQEQLRDGSRHPRSHQEDRAGHGHSAD 2621
+W S+ +S D R + S S+ R GSR + GH +
Sbjct: 981 SW-------QRSRSYSRDRSRSTRSPSQ----------RSGSR--------KRSWGHESP 1015
Query: 2622 SSRQSGTRHTQTSSGGQAASSHEQARSSAGERHGSHHQQSADSSR-------HSGIGHGQ 2674
R SG R S ++ S H RS GE G D S+ +S IG G+
Sbjct: 1016 EERHSGRRDFIRSKIYRSQSPH-YFRSGRGEGPGKKDDGRGDDSKATGPPSQNSNIGTGR 1074
Query: 2675 AS 2676
S
Sbjct: 1075 GS 1076
Score = 82.4 bits (202), Expect = 8e-15
Identities = 155/748 (20%), Positives = 250/748 (33%), Gaps = 121/748 (16%)
Query: 2270 SAQEQSRDGSRHPRSHHEDRAGHGHSAESSRQSGTHHAENSSGGQAASSHEQARSSAGER 2329
++++ D + HP++ E + G +S ++ + + + ++ +
Sbjct: 416 ASEQMDGDNTTHPKNAPESKKGSSPKPKSCIKAAASQGAEKTVSEVSEQPKETSMTEPSE 475
Query: 2330 HGSHHQQSADSSRHSGIGHGQASSAVRDSGHRGSSGSQASDSEGHSEDSDTQSVSAHGQA 2389
GS A++ + G G S +S + S +Q +S E S Q
Sbjct: 476 PGS----KAEAKKALG---GDVSDQSLESHSQKVSETQMCESNSSKETSLATPAGKESQE 528
Query: 2390 GPHQQ--------SHQESTRGR-------------SAGRSGRSGSFLYQVSTHEQSESAH 2428
GP S EST + S S F +++S ++ + +
Sbjct: 529 GPKHPTGPFFPVLSKDESTALQWPSELLIFTKAEPSISYSCNPLYFDFKLSRNKDARTK- 587
Query: 2429 GRTGTSTGGRQGSHHKQARDSSRHSTSQE--GQDTIHGHPGSSSGGRQ------------ 2474
G G H Q D + S+E G+ + SSGGR
Sbjct: 588 GTEKPKDIGSSSKDHLQGLDPGEPNKSKEVGGEKIVR-----SSGGRMDAPASGSACSGL 642
Query: 2475 ------GSHYEQLVDRSGHSGSHHSHTTSQGRSDASHGHSGSRSASRQTRNDEQSGDGSR 2528
GSH + D S + R H S R+ + D +
Sbjct: 643 NKQEPGGSHGSETEDTGRSLPSKKERSGKSHRHKKKKKHKKSSKHKRKHKADTEEKSSKA 702
Query: 2529 HSGSRHHEASSRADSSGHSQVGQGQSEGPRTSRNWGSSFSQDSDSQGHSEDSERWSGSAS 2588
SG + + R S GP+ S + + +DS+R S A
Sbjct: 703 ESGEKSKKRKKRKRKKNKSSAPADSERGPKPEPPGSGSPAPPRRRRRAQDDSQRRSLPAE 762
Query: 2589 RNHHGSAQEQLRDGSRHPRSHQEDRAGHGHSADSSRQSGTRHTQTSSGGQAASSHEQARS 2648
G E S +D G H + S R T + SSH S
Sbjct: 763 EGSSGKKDE------GGGGSSSQDHGGRKHKGELPPSSCQRRAGTKRSSR--SSHRSQPS 814
Query: 2649 SAGERHGSHHQQSADSSRHSGIGHGQASSAVRDSGHRGYSGSQASDNEGHSEDSDTQSVS 2708
S E S D+S H + YS + ++ G SE S ++S
Sbjct: 815 SGDE-------DSDDASSH----------RLHQKSPSQYSEEEEEEDSG-SEHSRSRS-- 854
Query: 2709 AHGQAGSHQQSHQESARGRSGETSGHSGSFLYQVSTHEQSESSHGWTGPSTRGRQGSRHE 2768
++G SH+ S R S + S Y + ++S S ++ S R R+ S+
Sbjct: 855 ---RSGRRHSSHRSSRRSYSSSSDASSDQSCY---SRQRSYSDDSYSDYSDRSRRHSKRS 908
Query: 2769 QAQDSSRHSASQDGQDTIRGHPGSSRGGRQGYHHEHSVDSSGHSGSHHSHTTSQGRSDAS 2828
D S +++S+ S R ++S+ S SHT + R S
Sbjct: 909 HDSDDSDYASSKH---------RSKRHKYSSSDDDYSLSCSQSRSRSRSHTRERSR---S 956
Query: 2829 RGQSGSRSASRTTRNEEQSGDGSRHSGSRHHEASTHADISRHSQAVQGQSEGSRRSRRQG 2888
RG+S S S SR +R++ +S + HS R S D SR +++ Q GSR+
Sbjct: 957 RGRSRSSSCSR-SRSKRRSRSTTAHSWQRSRSYS--RDRSRSTRS-PSQRSGSRKR---- 1008
Query: 2889 SSVSQDSDSEGHSEDSERWSGS----ASRNHHGSAQEQLRDGSRHPRSHQEDRAGHGHSA 2944
S GH ER SG S+ + + R G ++D G A
Sbjct: 1009 --------SWGHESPEERHSGRRDFIRSKIYRSQSPHYFRSGRGEGPGKKDDGRGDDSKA 1060
Query: 2945 DSSRQSGTRHTQTSSGGQAASSHEQARS 2972
+ S + T G + S E S
Sbjct: 1061 -TGPPSQNSNIGTGRGSEGDCSPEDKNS 1087
Score = 80.9 bits (198), Expect = 2e-14
Identities = 137/622 (22%), Positives = 222/622 (35%), Gaps = 129/622 (20%)
Query: 876 SQGRSDASRGQSGSRSASRTTRNEEQSRDGSRHSGSRH--HEASSHADISRHSQAGQGQS 933
S+ + ++G + ++++ Q D + S+ E + R G +
Sbjct: 579 SRNKDARTKGTEKPKDIGSSSKDHLQGLDPGEPNKSKEVGGEKIVRSSGGRMDAPASGSA 638
Query: 934 EGSRTSRRQGSSVSQDSDSEGHSEDSERWSGSASRNHRGSAQEQSRHGSRHPRSHHEDRA 993
+ G S +++ G S S++ + ++HR +++ + S+H R H D
Sbjct: 639 CSGLNKQEPGGSHGSETEDTGRSLPSKK--ERSGKSHRHKKKKKHKKSSKHKRKHKADTE 696
Query: 994 GHGHSADSSRQSGTPHAETSSGGQAASSHEQARSSPGERHGS-------RHQQSADSSRH 1046
A+S +S ++++ + R E GS R +++ D S+
Sbjct: 697 EKSSKAESGEKSKKRKKRKRKKNKSSAPADSERGPKPEPPGSGSPAPPRRRRRAQDDSQR 756
Query: 1047 SGIPRRQASSAVRDSGHWGSSGSQASDSEGHSEESDTQSVSGHGQDGPHQQSHQESARDW 1106
+P + SS +D G G S S+ H
Sbjct: 757 RSLPAEEGSSGKKDEGGGG------SSSQDH----------------------------- 781
Query: 1107 SGGRSGRSGSFIYQVSTHEQSESAHGRTRTSTGRRQGSHHEQARDSSRHSASQEGQDTIR 1166
GGR + + + + R T R S H S+ S+ E D
Sbjct: 782 -GGRKHKG-----------ELPPSSCQRRAGTKRSSRSSHR-----SQPSSGDEDSDDAS 824
Query: 1167 AHPGSRRGGRQGSHHEQSVDRSGHSGSHHSHTTSQGRSDASHGQSGSRSASRQTRKDKQS 1226
+H ++ Q S E+ D SGS HS R +S
Sbjct: 825 SHRLHQKSPSQYSEEEEEED----SGSEHS------------------------RSRSRS 856
Query: 1227 G-DGSRHSGSRHHEAASWADSSRHSQVGQEQS--------SGSRTSRH-QGSSVSQDSD- 1275
G S H SR ++S SS S +++S R+ RH + S S DSD
Sbjct: 857 GRRHSSHRSSRRSYSSSSDASSDQSCYSRQRSYSDDSYSDYSDRSRRHSKRSHDSDDSDY 916
Query: 1276 ------SERH----SDDSERLSGSASRNHHGSSREQSRDGSRHPGFHQEDRASHGHSADS 1325
S+RH SDD LS S SR+ SR +R+ SR G + S S
Sbjct: 917 ASSKHRSKRHKYSSSDDDYSLSCSQSRSR---SRSHTRERSRSRGRSRSSSCSRSRSKRR 973
Query: 1326 SRQSGTHHTESSSHGQAVSSHEQARS--SPGERHGSRHQ---QSADSSRHSGIGHRQASS 1380
SR + H + S S +++RS SP +R GSR + + RHSG S
Sbjct: 974 SRSTTAHSWQRSRS----YSRDRSRSTRSPSQRSGSRKRSWGHESPEERHSGRRDFIRSK 1029
Query: 1381 AVR-DSGHRGSSGSQVTNSEGHSEDSDTQSVSAHGQAGPHQQSHKESARGQSGESSGRSR 1439
R S H SG EG + D + + P Q S+ + RG G+ S +
Sbjct: 1030 IYRSQSPHYFRSG----RGEGPGKKDDGRGDDSKATGPPSQNSNIGTGRGSEGDCSPEDK 1085
Query: 1440 SFLYQVSSHEQSESTHGQTAPS 1461
+ + E+ +S + PS
Sbjct: 1086 NSVTAKLLLEKIQSRKVERKPS 1107
Score = 79.3 bits (194), Expect = 7e-14
Identities = 162/721 (22%), Positives = 256/721 (35%), Gaps = 92/721 (12%)
Query: 2743 STHEQS--ESSHGWTGPSTRGRQGSRHEQAQDSSRHSASQDGQDTIRGHPGSSRGGRQGY 2800
+TH ++ ES G + P + + Q + + S+ ++T P S G +
Sbjct: 425 TTHPKNAPESKKG-SSPKPKSCIKAAASQGAEKTVSEVSEQPKETSMTEP-SEPGSKAEA 482
Query: 2801 HHEHSVDSSGHSGSHHSHTTSQGRSDASRGQSGSRSASRTTRNEEQSGDGSRHSGSRHHE 2860
D S S HS S+ + S + S+ S T ++S +G +H
Sbjct: 483 KKALGGDVSDQSLESHSQKVSETQMCES---NSSKETSLATPAGKESQEGPKHPTGPFFP 539
Query: 2861 ASTHADISRHSQAVQGQSEGSRRSRRQGS------------SVSQDSDSEGHSEDSERWS 2908
+ + S A+Q SE ++ + S +S++ D+ + +
Sbjct: 540 VLSKDE----STALQWPSELLIFTKAEPSISYSCNPLYFDFKLSRNKDARTKGTEKPKDI 595
Query: 2909 GSASRNHHGSAQEQLRDGSRHPRSHQEDRAGHGHS---ADSSRQSGTRHTQTSSGGQAAS 2965
GS+S++H + S+ + R+ G A S SG + Q G +
Sbjct: 596 GSSSKDHLQGLDPGEPNKSKEVGGEKIVRSSGGRMDAPASGSACSGL-NKQEPGGSHGSE 654
Query: 2966 SHEQARS--SAGERHGSHHQQSADSSRHSGIGHGQASSA-VRDSGHRGYSGSQASDNEGH 3022
+ + RS S ER G H+ H + A + + SG ++ +
Sbjct: 655 TEDTGRSLPSKKERSGKSHRHKKKKKHKKSSKHKRKHKADTEEKSSKAESGEKSKKRKKR 714
Query: 3023 SEDSDTQSVSAHGQAGSHQQSHQESARGRSGETSGHSGSFLYQVSTHEQSESSHGWTGPS 3082
+ S A +S RG E G SGS + S + P+
Sbjct: 715 KRKKNKSSAPA------------DSERGPKPEPPG-SGSPAPPRRRRRAQDDSQRRSLPA 761
Query: 3083 TRGRQGSRHEQAQDSSRHSASQYGQDTIRGH-PGSSRGGRQGYHHEHSVDSSGHSGSHHS 3141
G G + E SS + +G +G P SS R G SH S
Sbjct: 762 EEGSSGKKDEGGGGSS---SQDHGGRKHKGELPPSSCQRRAG-------TKRSSRSSHRS 811
Query: 3142 HTTS--QGRSDASRGQSGSRSASRTTRNEEQSGDSSRHSVSRHHEASTHADISRHSQAVQ 3199
+S + DAS + +S S+ + EE+ S HS SR H+
Sbjct: 812 QPSSGDEDSDDASSHRLHQKSPSQYSEEEEEEDSGSEHSRSRSRSGRRHS---------- 861
Query: 3200 GQSEGSRRSRRQGSSVSQDSDSEGHSEDSERWSGSASRNHRGSVQEQSRHGSRHPRSHHE 3259
S RS R+ S S D+ S+ +R S S + ++SR S+ RSH
Sbjct: 862 -----SHRSSRRSYSSSSDASSDQSCYSRQR---SYSDDSYSDYSDRSRRHSK--RSHDS 911
Query: 3260 DRAGHGHSADRSRQSGTRHAETSSGGQAASSHEQARSSPGERHGSRHQQSADSSRHSGIP 3319
D + + S RS+ RH +SS + S Q+RS H +S SR S
Sbjct: 912 DDSDYASSKHRSK----RHKYSSSDDDYSLSCSQSRSR-SRSHTRERSRSRGRSRSSSCS 966
Query: 3320 RGQASSAVRDSRHWGSSGSQASDSEGHSEESDTQSVSGHGQAGPHQQSHQESARDRSGGR 3379
R S + R SR + Q S S T+S S + H ES +R GR
Sbjct: 967 R---SRSKRRSRSTTAHSWQRSRSYSRDRSRSTRSPSQRSGSRKRSWGH-ESPEERHSGR 1022
Query: 3380 SGRSGSFLYQVSTHEQSESAHGRTRTSTGRRQGSHHEQARDSSRHSASQEGQDTIRGHPG 3439
S +Y +S+S H R+ G G + D S+ + I G
Sbjct: 1023 RDFIRSKIY------RSQSPH-YFRSGRGEGPGKKDDGRGDDSKATGPPSQNSNIGTGRG 1075
Query: 3440 S 3440
S
Sbjct: 1076 S 1076
Score = 78.2 bits (191), Expect = 2e-13
Identities = 114/494 (23%), Positives = 176/494 (35%), Gaps = 96/494 (19%)
Query: 3508 EASTQADSSRHSQSGQGQSAGPRTSRNQGSSVSQDSDSQGHSEDSERWSGSASRNHRGSA 3567
E ++ R G + + G S +++ G S S++ + ++HR
Sbjct: 620 EKIVRSSGGRMDAPASGSACSGLNKQEPGGSHGSETEDTGRSLPSKK--ERSGKSHRHKK 677
Query: 3568 QEQSRDGSRHPTSHHEDRAGHGHSAESSRQSGTHHAENSSGGQAASSHEQARSSAGERHG 3627
+++ + S+H H D AES +S ++++ + R E G
Sbjct: 678 KKKHKKSSKHKRKHKADTEEKSSKAESGEKSKKRKKRKRKKNKSSAPADSERGPKPEPPG 737
Query: 3628 S-------HHQQSADSSRHSGIGHGQASSAVRDSGHRGSSGSQASDSEGHSEDSDTQSVS 3680
S +++ D S+ + + SS +D G GSS + D G + S
Sbjct: 738 SGSPAPPRRRRRAQDDSQRRSLPAEEGSSGKKDEGGGGSS---SQDHGGRKHKGELPPSS 794
Query: 3681 AHGQAGPHQQSHQESTRGRSAGRSGRSGSFLYQVSTHEQSESAHGRAGPSTGGRQGSRHE 3740
+AG T S S+H R+ PS+G E
Sbjct: 795 CQRRAG-----------------------------TKRSSRSSH-RSQPSSGD------E 818
Query: 3741 QARDSSRHSASQEGQDTIRGHPGSRRGGRQGSYHEQSVDRSGHSGSHHSHTTSQ-GRSDA 3799
+ D+S H Q+ Q S E+ D SGS HS + S+ GR +
Sbjct: 819 DSDDASSHRLHQKSPS-------------QYSEEEEEED----SGSEHSRSRSRSGRRHS 861
Query: 3800 SHGQSGSRSASRETRNEEQSGDGSRHSGSRHHEASTQAD----SSRHSQ----SGQGESA 3851
SH +S RS S + + S D S +S R + + +D S RHS+ S + A
Sbjct: 862 SH-RSSRRSYS---SSSDASSDQSCYSRQRSYSDDSYSDYSDRSRRHSKRSHDSDDSDYA 917
Query: 3852 GSRRSRRQGSSVSQDSDSEAYPEDSERRSESASRNH---HGSSREQSRDGSRHPGSSHRD 3908
S+ ++ S D D S RS S +R G SR S SR S
Sbjct: 918 SSKHRSKRHKYSSSDDDYSLSCSQSRSRSRSHTRERSRSRGRSRSSSCSRSRSKRRSRST 977
Query: 3909 TA-------------SHVQSSPVQSDSSTAKEHGHFSSLSQDSAYHSGIQSRGSPHSSSS 3955
TA S SP Q S + GH S + S I+S+ + S S
Sbjct: 978 TAHSWQRSRSYSRDRSRSTRSPSQRSGSRKRSWGHESPEERHSGRRDFIRSK--IYRSQS 1035
Query: 3956 YHYQSEGTERQKGQ 3969
HY G G+
Sbjct: 1036 PHYFRSGRGEGPGK 1049
Score = 78.2 bits (191), Expect = 2e-13
Identities = 120/489 (24%), Positives = 180/489 (36%), Gaps = 63/489 (12%)
Query: 139 GRS-KSPRETGGKRHESSSEKKERKGYSPTHREEEYGKNHHNSSKKEKNKTENTRLGDNR 197
GRS S +E GK H +KK +K S H+ + SSK E + R R
Sbjct: 659 GRSLPSKKERSGKSHRHKKKKKHKK--SSKHKRKHKADTEEKSSKAESGEKSKKR--KKR 714
Query: 198 KRLSERLEEKEDNEEGVYDYENTGRMTQKWIQSGHIATYYTIQDEAYDTTDSLL--EENK 255
KR + D+E G E G SG A + D+ L EE
Sbjct: 715 KRKKNKSSAPADSERGPKP-EPPG--------SGSPAPPRRRRRAQDDSQRRSLPAEEGS 765
Query: 256 IYERSRSSDGKSSSQVNRSRHENTSQVPLQESRTRKRRGSRVSQDRDSEGHSEDSERHSG 315
++ G SS +H+ + R +R SR
Sbjct: 766 SGKKDEGGGGSSSQDHGGRKHKGELPPSSCQRRAGTKRSSR------------------- 806
Query: 316 SASRNHHGSAWEQSRDGSRHPRSHDEDRASHGHSADSSRQSGTRHAETSSRGQTASSHEQ 375
S+ R+ S E S D S H R H ++S ++++E + S H +
Sbjct: 807 SSHRSQPSSGDEDSDDASSH-RLH--------------QKSPSQYSEEEEEEDSGSEHSR 851
Query: 376 ARSSPGERHGSGHQQSADSSRHSATGRGQASSAVSDRGHRGSSGSQASD-SEGHSENSDT 434
+RS G RH S H+ S S S+ S R + S S SD S HS+ S
Sbjct: 852 SRSRSGRRH-SSHRSSRRSYSSSSDASSDQSCYSRQRSYSDDSYSDYSDRSRRHSKRSHD 910
Query: 435 QSVSGHGKAGLRQQSHQESTRGRSGERSGRSGSSLYQVSTHEQPDSAHGRTGTSTGGRQG 494
S + + R + H+ S+ S S + T E+ S GR+ +S+ R
Sbjct: 911 SDDSDYASSKHRSKRHKYSSSDDDYSLSCSQSRSRSRSHTRERSRS-RGRSRSSSCSRSR 969
Query: 495 SHHEQARDSSRHSASQEGQDTIRGHPGSSRGGRQGSHHEQSVNRS-GHSGSHHSHTTSQG 553
S ++R ++ HS Q + R SR R S S RS GH H+ G
Sbjct: 970 S-KRRSRSTTAHS-WQRSRSYSRDR---SRSTRSPSQRSGSRKRSWGHESPEERHS---G 1021
Query: 554 RSDASHGQSGSRSASRQTRNEEQSGDGTRHSGSRHHEASSQADSSRHSQVGQGQSSGPRT 613
R D + + R+ G G + G R ++ + S++S +G G+ S
Sbjct: 1022 RRDFIRSKIYRSQSPHYFRSGRGEGPGKKDDG-RGDDSKATGPPSQNSNIGTGRGSEGDC 1080
Query: 614 SRNQGSSVS 622
S +SV+
Sbjct: 1081 SPEDKNSVT 1089
Score = 77.4 bits (189), Expect = 3e-13
Identities = 134/644 (20%), Positives = 233/644 (36%), Gaps = 74/644 (11%)
Query: 505 RHSASQEGQDTIRGHPGSSRGGRQGSHHEQS--VNRSGHSGSHHSHTTSQGRSDASHGQS 562
R S +G +T HP ++ ++GS + + + G+ + + + +
Sbjct: 415 RASEQMDGDNTT--HPKNAPESKKGSSPKPKSCIKAAASQGAEKTVSEVSEQPKETSMTE 472
Query: 563 GSRSASRQTRNEEQSGDGTRHSGSRHH---------EASSQADSSRHSQVGQGQSSGPR- 612
S S+ + GD + S H E++S ++S + G+ GP+
Sbjct: 473 PSEPGSKAEAKKALGGDVSDQSLESHSQKVSETQMCESNSSKETSLATPAGKESQEGPKH 532
Query: 613 --------TSRNQGSSVSQDSDSQGHSEDSERWSGSASRNHHGSAQEQSRD----GSRHP 660
S+++ +++ S+ ++ S S + + +++D G+ P
Sbjct: 533 PTGPFFPVLSKDESTALQWPSELLIFTKAEPSISYSCNPLYFDFKLSRNKDARTKGTEKP 592
Query: 661 RSHHEDRAGHGHSAD-----SSRKSGTRHTQNSSSGQ--AASSHEQARSSAGERHGSRHQ 713
+ H D S++ G SS G+ A +S + G H
Sbjct: 593 KDIGSSSKDHLQGLDPGEPNKSKEVGGEKIVRSSGGRMDAPASGSACSGLNKQEPGGSHG 652
Query: 714 LQSADSSRHSGTGHGQASSAVRDSGHRGSSGSQATDSEGHSEDSDTQSVSGHGQAGHHQQ 773
++ D+ R + ++ + R H+ + + +DT+ S ++G +
Sbjct: 653 SETEDTGRSLPSKKERSGKSHR---HKKKKKHKKSSKHKRKHKADTEEKSSKAESGEKSK 709
Query: 774 SHQESARDRSGERSRRSGSFLYQVSTHKQSESSHGWTGPSTGVRQGSHHEQARDNSRHSA 833
++ R ++ +S + K G P R+ Q R
Sbjct: 710 KRKKRKRKKN-----KSSAPADSERGPKPEPPGSGSPAPPRRRRRAQDDSQRRSLPAEEG 764
Query: 834 SQDGQDTIRGHPGSSRRGRQGSHHEQSVD------RSGHSGSHHSHTTSQGRS------D 881
S +D G GSS + G H+ + R+G S S SQ S D
Sbjct: 765 SSGKKD--EGGGGSSSQDHGGRKHKGELPPSSCQRRAGTKRSSRSSHRSQPSSGDEDSDD 822
Query: 882 ASRGQSGSRSASRTTRNEEQSRDGSRHSGSRHHEASSHAD--ISRHSQAGQGQSEGSRTS 939
AS + +S S+ + EE+ GS HS SR H+ SR S + + ++
Sbjct: 823 ASSHRLHQKSPSQYSEEEEEEDSGSEHSRSRSRSGRRHSSHRSSRRSYSSSSDASSDQSC 882
Query: 940 RRQGSSVSQDSDSEGHSEDSERWSGSASRNHRGSAQEQSRHGS-RHPRSHHEDRAGHGHS 998
+ S S DS S+ +S+ S R S S + S S+H S RH S +D S
Sbjct: 883 YSRQRSYSDDSYSD-YSDRSRRHS-KRSHDSDDSDYASSKHRSKRHKYSSSDDDYSLSCS 940
Query: 999 ADSSR-QSGTPHAETSSGGQAASSHEQARSSPGERHGSRH------QQSADSSRHSGIPR 1051
SR +S T S G +SS ++RS R + H S D SR + P
Sbjct: 941 QSRSRSRSHTRERSRSRGRSRSSSCSRSRSKRRSRSTTAHSWQRSRSYSRDRSRSTRSPS 1000
Query: 1052 RQASSAVRDSGHWGSSGSQASDSEGHSEESDTQSVSGHGQDGPH 1095
+++ S R GH S E HS D + PH
Sbjct: 1001 QRSGSRKRSWGH-------ESPEERHSGRRDFIRSKIYRSQSPH 1037
Score = 75.1 bits (183), Expect = 1e-12
Identities = 99/431 (22%), Positives = 153/431 (35%), Gaps = 57/431 (13%)
Query: 252 EENKIYERSRSSDGKSSSQVNRSRHENTSQVPLQESRTRKRRGSRVSQDRDSEGHSEDSE 311
++ K +++S K + + S ++ + RKR+ ++ S DSE +
Sbjct: 676 KKKKKHKKSSKHKRKHKADTEEKSSKAESGEKSKKRKKRKRKKNKSSAPADSERGPKPEP 735
Query: 312 RHSGS-ASRNHHGSAWEQSRDGSRHPRSHDEDRASHGHSADSSRQSGTRHAE----TSSR 366
SGS A A + S+ S + G SS+ G R + SS
Sbjct: 736 PGSGSPAPPRRRRRAQDDSQRRSLPAEEGSSGKKDEGGGGSSSQDHGGRKHKGELPPSSC 795
Query: 367 GQTASSHEQARSSPGERHGSGHQQSADSSRHSATGRGQASSAVSDRGHRGSSGSQASDSE 426
+ A + +RSS + SG + S D+S H R H+ S SQ S+ E
Sbjct: 796 QRRAGTKRSSRSSHRSQPSSGDEDSDDASSH--------------RLHQ-KSPSQYSEEE 840
Query: 427 GHSENSDTQSVSGHGKAGLRQQSHQESTRGRSGERSGRSGSSLYQVSTHEQPDSAHGRTG 486
E+S ++ ++G R SH+ S R S S S Y DS +
Sbjct: 841 -EEEDSGSEHSRSRSRSGRRHSSHRSSRRSYSSSSDASSDQSCYSRQRSYSDDSYSDYSD 899
Query: 487 TSTGGRQGSHHEQARD-------SSRHSASQEGQD-TIRGHPGSSRGGRQGSHHEQSVNR 538
S + SH D S RH S D ++ SR +S R
Sbjct: 900 RSRRHSKRSHDSDDSDYASSKHRSKRHKYSSSDDDYSLSCSQSRSRSRSHTRERSRSRGR 959
Query: 539 SGHSGSHHSHTTSQGRSDASHG----QSGSRSASRQTRNEEQSGDGT-----------RH 583
S S S + + RS +H +S SR SR TR+ Q RH
Sbjct: 960 SRSSSCSRSRSKRRSRSTTAHSWQRSRSYSRDRSRSTRSPSQRSGSRKRSWGHESPEERH 1019
Query: 584 SGSR-------------HHEASSQADSSRHSQVGQGQSSGPRTSRNQGSSVSQDSDSQGH 630
SG R H+ S + + G+G S +Q S++ S+G
Sbjct: 1020 SGRRDFIRSKIYRSQSPHYFRSGRGEGPGKKDDGRGDDSKATGPPSQNSNIGTGRGSEGD 1079
Query: 631 SEDSERWSGSA 641
++ S +A
Sbjct: 1080 CSPEDKNSVTA 1090
Score = 73.2 bits (178), Expect = 5e-12
Identities = 122/534 (22%), Positives = 191/534 (35%), Gaps = 89/534 (16%)
Query: 3566 SAQEQSRDGSRHPTSHHEDRAGHGHSAESSRQSGTHHAENSSGGQAASSHEQARSSAGER 3625
++++ D + HP + E + G +S ++ + + + ++ +
Sbjct: 416 ASEQMDGDNTTHPKNAPESKKGSSPKPKSCIKAAASQGAEKTVSEVSEQPKETSMTEPSE 475
Query: 3626 HGSHHQQSADSSRHSGIGHGQASSAVRDSGHRGSSGSQASDSEGHSEDSDTQSVSAHGQA 3685
GS A++ + G G S +S + S +Q +S E S Q
Sbjct: 476 PGS----KAEAKKALG---GDVSDQSLESHSQKVSETQMCESNSSKETSLATPAGKESQE 528
Query: 3686 GPHQQ--------SHQESTRGR-------------SAGRSGRSGSFLYQVSTHEQSESAH 3724
GP S EST + S S F +++S ++ + +
Sbjct: 529 GPKHPTGPFFPVLSKDESTALQWPSELLIFTKAEPSISYSCNPLYFDFKLSRNKDARTK- 587
Query: 3725 GRAGPSTGGRQGSRHEQARDSSRHSASQE--GQDTIRGHPGSRRGGRQGSYHEQSVDRSG 3782
G P G H Q D + S+E G+ +R G GS +++
Sbjct: 588 GTEKPKDIGSSSKDHLQGLDPGEPNKSKEVGGEKIVRSSGGRMDAPASGSACS-GLNKQE 646
Query: 3783 HSGSHHSHTTSQGRSDASHGQSGSRSASRETRNEEQSGDGSRHSGSRHHEASTQADSSRH 3842
GSH S T GRS S + +S + + + + S+H R H+A T+ SS+
Sbjct: 647 PGGSHGSETEDTGRSLPSKKERSGKSHRHKKKKKHKKS--SKHK--RKHKADTEEKSSKA 702
Query: 3843 SQSGQGESAGSRRSRRQGSSVSQDSDSEAYPE------------------DSERRSESAS 3884
+ + R+ ++ SS DS+ PE DS+RRS A
Sbjct: 703 ESGEKSKKRKKRKRKKNKSSAPADSERGPKPEPPGSGSPAPPRRRRRAQDDSQRRSLPAE 762
Query: 3885 RNHHGSSRE-------QSRDGSRHPGS-----------SHRDTASHVQSSPVQSD--SST 3924
G E Q G +H G + R + S +S P D S
Sbjct: 763 EGSSGKKDEGGGGSSSQDHGGRKHKGELPPSSCQRRAGTKRSSRSSHRSQPSSGDEDSDD 822
Query: 3925 AKEHG-HFSSLSQDS---------AYHSGIQSR-GSPHSS--SSYHYQSEGTERQKGQSG 3971
A H H S SQ S + HS +SR G HSS SS S ++ QS
Sbjct: 823 ASSHRLHQKSPSQYSEEEEEEDSGSEHSRSRSRSGRRHSSHRSSRRSYSSSSDASSDQS- 881
Query: 3972 LVWRHGSYGSADY-DYGESGFRHSQHGSVSYNSNPVVFKERSDICKASAFGKDH 4024
R SY Y DY + RHS+ S +S+ K RS K S+ D+
Sbjct: 882 CYSRQRSYSDDSYSDYSDRSRRHSKRSHDSDDSDYASSKHRSKRHKYSSSDDDY 935
Score = 68.9 bits (167), Expect = 9e-11
Identities = 93/435 (21%), Positives = 166/435 (38%), Gaps = 57/435 (13%)
Query: 83 QAYYESTRKENLPISGHKHRKHSHHDKHEDNKQEENKENRKRPSSLERRNNRKGNKGRSK 142
+++ +K++ S HK RKH + + +K E ++++KR ++ RK NK +
Sbjct: 671 KSHRHKKKKKHKKSSKHK-RKHKADTEEKSSKAESGEKSKKR-----KKRKRKKNKSSAP 724
Query: 143 SPRETGGKRHESSS-----EKKERKGYSPTHREEEYGKNHHNSSKKEKNKTENTRLGDNR 197
+ E G K S ++ R+ + R + + K E +++ R
Sbjct: 725 ADSERGPKPEPPGSGSPAPPRRRRRAQDDSQRRSLPAEEGSSGKKDEGGGGSSSQDHGGR 784
Query: 198 KRLSERLEEKEDNEEGVYDYENTGRMTQKWIQSGHIATYYTIQDEAYDTTDSLLEENKIY 257
K E G T++ +S H + + +++ D + L +
Sbjct: 785 KHKGELPPSSCQRRAG----------TKRSSRSSHRSQPSSGDEDSDDASSHRLHQ---- 830
Query: 258 ERSRSSDGKSSSQVNRSRHENTSQVPLQESRTRKRRGSRVSQDRDS-EGHSEDSERHSG- 315
KS SQ + E S + SR+R R G R S R S +S S+ S
Sbjct: 831 --------KSPSQYSEEEEEEDS--GSEHSRSRSRSGRRHSSHRSSRRSYSSSSDASSDQ 880
Query: 316 ---SASRNHHGSAWEQSRDGSRH--PRSHDEDRASHGHSADSSRQSGTRHAETSSRGQTA 370
S R++ ++ D SR RSHD D + + S S++ ++ +
Sbjct: 881 SCYSRQRSYSDDSYSDYSDRSRRHSKRSHDSDDSDYASSKHRSKRHKYSSSDDDYSLSCS 940
Query: 371 SSHEQARSSPGERHGS-GHQQSADSSRHSATGRGQASSAVSDRGHRGSSGSQASDSEGHS 429
S ++RS ER S G +S+ SR + R ++++A S + R S ++ + S
Sbjct: 941 QSRSRSRSHTRERSRSRGRSRSSSCSRSRSKRRSRSTTAHSWQRSRSYSRDRSRSTRSPS 1000
Query: 430 ENSDTQSVS-GHGKAGLRQQSHQESTRGR-------------SGERSGRSGSSLYQVSTH 475
+ S ++ S GH R ++ R + GE G+ S
Sbjct: 1001 QRSGSRKRSWGHESPEERHSGRRDFIRSKIYRSQSPHYFRSGRGEGPGKKDDGRGDDSKA 1060
Query: 476 EQPDSAHGRTGTSTG 490
P S + GT G
Sbjct: 1061 TGPPSQNSNIGTGRG 1075
Score = 67.0 bits (162), Expect = 4e-10
Identities = 119/559 (21%), Positives = 199/559 (35%), Gaps = 59/559 (10%)
Query: 3453 SVDRSGHSGSHHSHTTSQGRSDASRGQSGSRSASRQTRNDEQSGDGSRHSWSHHHEASTQ 3512
S G + +H + + + + +S ++A+ Q G+ + S E +
Sbjct: 417 SEQMDGDNTTHPKNAPESKKGSSPKPKSCIKAAASQ---------GAEKTVSEVSEQPKE 467
Query: 3513 ADSSRHSQSGQGQSAGPRTSRNQGSSVSQDSDSQGHSEDSERWSGSASRNHRGS-AQEQS 3571
+ S+ G A + S S +S SQ SE S S+ + A ++S
Sbjct: 468 TSMTEPSEPGSKAEA-KKALGGDVSDQSLESHSQKVSETQMCESNSSKETSLATPAGKES 526
Query: 3572 RDGSRHPT-------SHHEDRAGHGHSA----ESSRQSGTHHAENSSGGQAASSHEQARS 3620
++G +HPT S E A S + S ++ S ++ AR+
Sbjct: 527 QEGPKHPTGPFFPVLSKDESTALQWPSELLIFTKAEPSISYSCNPLYFDFKLSRNKDART 586
Query: 3621 SAGERHGSHHQQSADSSRHSGIGHGQASSAVRDSGH---RGSSGSQASDSEGHSEDSDTQ 3677
E+ S D + G+ G+ + + G R S G + + G S
Sbjct: 587 KGTEKPKDIGSSSKDHLQ--GLDPGEPNKSKEVGGEKIVRSSGGRMDAPASG----SACS 640
Query: 3678 SVSAHGQAGPHQQSHQESTRGRSAGRSGRSGSFLYQVSTHEQSESAHGRAGPSTGGRQGS 3737
++ G H +++ R + + S ++ + S H R + + S
Sbjct: 641 GLNKQEPGGSHGSETEDTGRSLPSKKERSGKSHRHKKKKKHKKSSKHKRKHKADTEEKSS 700
Query: 3738 RHEQARDSSRHSASQEGQDTIRGHPGSRRGGRQGSYHEQSVDRSGHSGSHHSHTTSQGRS 3797
+ E S + + ++ S RG + + G + +
Sbjct: 701 KAESGEKSKKRKKRKRKKNKSSAPADSERGPKP--------EPPGSGSPAPPRRRRRAQD 752
Query: 3798 DASHGQSGSRSASRETRNEEQSGDGSRHSGSRHHEASTQADSSRHSQSGQGESAGSRRSR 3857
D+ + S ++E G S+ G R H+ S + + S S RS
Sbjct: 753 DSQRRSLPAEEGSSGKKDEGGGGSSSQDHGGRKHKGELPPSSCQRRAGTKRSSRSSHRS- 811
Query: 3858 RQGSSVSQDSDSEA----YPEDSERRSESASRNHHGS--SREQSRDGSRHPGSSHRDTA- 3910
Q SS +DSD + + + + SE GS SR +SR G RH SSHR +
Sbjct: 812 -QPSSGDEDSDDASSHRLHQKSPSQYSEEEEEEDSGSEHSRSRSRSGRRH--SSHRSSRR 868
Query: 3911 SHVQSSPVQSDSSTAKEHGHFSSLSQDSAYHSGIQSRGSPHSSSSYHYQSEGTERQKGQS 3970
S+ SS SD S + S S DS +S R HS S+ K +S
Sbjct: 869 SYSSSSDASSDQSC---YSRQRSYSDDS--YSDYSDRSRRHSKRSHDSDDSDYASSKHRS 923
Query: 3971 GLVWRHGSYGSADYDYGES 3989
RH Y S+D DY S
Sbjct: 924 K---RH-KYSSSDDDYSLS 938
>gi|224548936 hypothetical protein LOC100170229 [Homo sapiens]
Length = 715
Score = 98.2 bits (243), Expect = 1e-19
Identities = 152/689 (22%), Positives = 233/689 (33%), Gaps = 57/689 (8%)
Query: 2054 SDTQSVSAQGKAGPHQQSHKESARGQSGESSGRSGSFLYQVSTHEQSESTHGQSAPSTGG 2113
S + S S + + S++ S+R + S R+ S +VST ++ S
Sbjct: 58 SPSSSKSTKSTSTKRAPSNRPSSRSRV-RSKARTPS---RVSTDTRTSKASKASDVRCHQ 113
Query: 2114 RQGSHYDQAQDSSRHSASQEGQDTIRGHPGPSR--GGRQGSHQEQSVDRSGHSGSHHSHT 2171
R+G+H R S S + + PG R G R G S GS
Sbjct: 114 RRGTHSRGRTPGRRGSRSSKRSPSRASTPGRIRTHGARPGMASRVRTPTSQQKGSRGKSY 173
Query: 2172 TSQGRSDASRGQSGSRSASRKTYDKEQSGDGSRHSGSHHHEASSWADSSRHSLVGQGQSS 2231
S+ R S R+ S+K+Y + G G S S+ + + + +S
Sbjct: 174 GRPRTSNRERSDSQPRNLSKKSY-RPPGGSGIGRSSELAVTPSTAKCQTPTGIPSKEKSD 232
Query: 2232 GPRTSRPRG-SSVSQDSDSEGHSEDSERRSGSASRNHHGSA---QEQSRDGSRHPRSHHE 2287
P S R S Q S S ++++ ++ + QS SR PR
Sbjct: 233 NPSPSSSRKVKSYGQMIIPSREKSYSPTEMSSRVKSYNQASTRSRPQSHSQSRSPRRSRS 292
Query: 2288 DRAGHGHSAESSRQSGTHHAENSSGGQAASSHEQARSSAGERHGSHHQQSADSSRHSGIG 2347
HS S +H+ S + + R S H Q+ + G
Sbjct: 293 GSQKRTHSRVRSHSWKRNHSRARSRTRKGILSQMGRHSQSRSHSKGKSQNQSRTPRRGRS 352
Query: 2348 HGQASSAVRDSGHRGSSGSQASDSEGHSEDSDTQSVSAHGQAG-PHQQSHQESTRGRSAG 2406
H + + ++ H S S S H S + S Q+G P++Q +R +
Sbjct: 353 HNWSRNPSKERSHSHSRSS--SKERDHRGSSSPRKESGRSQSGSPNKQRDHSRSRSPNKA 410
Query: 2407 RSGRSGSFLYQVSTHEQSESAHGRTGTSTGGRQGSHHKQARDSSRHSTSQEGQDTIHGHP 2466
R Y+ +S S + S R S +K ARD SR + + +D H
Sbjct: 411 RDRSRSRSPYKARDRSRSRSPNKARDCS---RSRSPYK-ARDRSRSRSPNKARD--HSRS 464
Query: 2467 GSSSGGRQGSHYEQLVDRSGHSGSHHSHTTSQGRSDASHGHSGSRSASRQTRNDEQSGDG 2526
S + R S RS HS S + + H S S S RQ R S
Sbjct: 465 RSPNKARDRSR-----SRSPSKERDHSQLGSPSK-ERDHRRSRSPSKERQCRQSRSSSKE 518
Query: 2527 SRHSGSR--HHEASSRADSSGHSQVGQGQSEGPRTSRNWGSSFSQDSDSQGHSEDSERW- 2583
H SR E R S + + + QS P R + S S D RW
Sbjct: 519 RDHRRSRSPSKERQRRQSRSPNKERDRSQSRSPSEERE-----HRQSRSPSKERDRRRWR 573
Query: 2584 ------------SGSASRNHHGSAQEQLRDGSRHPRSHQEDRAGHGHSADSSRQSGTRHT 2631
S S R+H S + G PR+ +++A H S S++ +
Sbjct: 574 SPSKERERRQSRSSSEERDHSRSRSPNKQSGYSRPRASSKEKA-HSRSRTPSKEGNHSQS 632
Query: 2632 QTSSGGQAASSHEQARSSAGERHGSHHQQSADSSRHSGIGHGQASSAVRDSGHRGY-SGS 2690
+TSS S RS +R +R S + + S + SG
Sbjct: 633 RTSSKESDPSQSTVPRSPDWKR---------SPTRTSSLSQNRTPSKTSSHSPSTFPSGG 683
Query: 2691 QASDNEGHSEDSDTQSVSAHGQAGSHQQS 2719
Q + D+ T + G+ S S
Sbjct: 684 QTLSQDDSQADATTSKATLPGERSSSSSS 712
Score = 95.9 bits (237), Expect = 7e-19
Identities = 165/707 (23%), Positives = 248/707 (35%), Gaps = 130/707 (18%)
Query: 3276 TRHAETSSGGQAASSHEQARSSPGERHGSRHQQSADSSRHSGIPRGQASSAVRDSRHWGS 3335
T+ A + + + SS + +S+ +R S S R + S+ R S+
Sbjct: 47 TKPATSRNSVMSPSSSKSTKSTSTKRAPSNRPSSRSRVRSKARTPSRVSTDTRTSK---- 102
Query: 3336 SGSQASDSEGHSEESDTQSVSGHGQAGPHQQSHQESAR-DRSGGRSGRSGSFLYQVSTHE 3394
S+ASD V H + G H + R RS RS S ++ TH
Sbjct: 103 -ASKASD------------VRCHQRRGTHSRGRTPGRRGSRSSKRSPSRASTPGRIRTHG 149
Query: 3395 QSESAHGRTRTSTGRRQGSH---HEQARDSSRHSASQEGQDTIRGH---PGSSRRGRQGS 3448
R RT T +++GS + + R S+R + + ++ + PG S GR
Sbjct: 150 ARPGMASRVRTPTSQQKGSRGKSYGRPRTSNRERSDSQPRNLSKKSYRPPGGSGIGRSS- 208
Query: 3449 HYEQSVDRSGHSGSHHSHTTSQGRSDASRGQSGSRSASRQTRNDEQSGDGSRHSWSHHHE 3508
E +V S + S+ +SD + S S+SR+ ++ Q SR E
Sbjct: 209 --ELAVTPSTAKCQTPTGIPSKEKSD-----NPSPSSSRKVKSYGQMIIPSREKSYSPTE 261
Query: 3509 ASTQADS-----SRHSQSGQGQSAGPRTSRNQGSSVSQDSDSQGHSEDSERWSGSASRNH 3563
S++ S +R QS PR SR+ GS S + HS W RNH
Sbjct: 262 MSSRVKSYNQASTRSRPQSHSQSRSPRRSRS-GSQKRTHSRVRSHS-----WK----RNH 311
Query: 3564 RGSAQEQSRDGSRHPTSHHEDRAGHGHSAESSRQSGTHHAENSSGGQAASSHEQARSSAG 3623
A+ ++R G H H +S QS T
Sbjct: 312 -SRARSRTRKGILSQMGRHSQSRSHS-KGKSQNQSRT----------------------- 346
Query: 3624 ERHGSHHQQSADSSRHSGIGHGQASSAVRDSGHRGSSGSQASDSEGHSEDSDTQSVSAHG 3683
R G H S + S+ H ++SS RD HRGSS + E +QS S +
Sbjct: 347 PRRGRSHNWSRNPSKERSHSHSRSSSKERD--HRGSSSPR-------KESGRSQSGSPNK 397
Query: 3684 QAGPHQQSHQESTRGRSAGRSGRSGSFLYQVSTHEQSESAHGRAGPSTGGRQGSRHEQAR 3743
Q + R RS RS Y+ +S S + +AR
Sbjct: 398 QRDHSRSRSPNKARDRSRSRSP------YKARDRSRSRSPN----------------KAR 435
Query: 3744 DSSRHSASQEGQDTIRGHPGSRRGGRQGSYHEQSVDRSGHSGSHHSHTTSQGRSDASHGQ 3803
D SR + + +D R ++ + S RS + S + S + + H Q
Sbjct: 436 DCSRSRSPYKARDRSRSRSPNKA-------RDHSRSRSPNKARDRSRSRSPSK-ERDHSQ 487
Query: 3804 SGSRSASRETRNEEQSGDGSRHSGSRHHEASTQADSSRHSQSGQGESAGSRRSRRQGSSV 3863
GS S R+ R S S+ + SS+ + S R RRQ S
Sbjct: 488 LGSPSKERDHRRSR--------SPSKERQCRQSRSSSKERDHRRSRSPSKERQRRQSRSP 539
Query: 3864 SQDSDSEAYPEDSERRSESASRNHHGSSREQSRDGSRHPGSSHRDTASHVQSSPVQSDSS 3923
+++ D S+ RS S R H QSR S+ + S + SS
Sbjct: 540 NKERDR------SQSRSPSEEREHR-----QSRSPSKERDRRRWRSPSKERERRQSRSSS 588
Query: 3924 TAKEHGHFSSLSQDSAYHSGIQSRGSPHSSSSYHYQSEGTERQKGQS 3970
++H S ++ S Y S S S EG Q S
Sbjct: 589 EERDHSRSRSPNKQSGYSRPRASSKEKAHSRSRTPSKEGNHSQSRTS 635
Score = 95.1 bits (235), Expect = 1e-18
Identities = 184/763 (24%), Positives = 272/763 (35%), Gaps = 90/763 (11%)
Query: 267 SSSQVNRSRHENTSQVPLQESRTRKRRGSRVSQDRDSEGHSEDSERHSGSASRNHHGSAW 326
+S + +S N S VP + + +R + V S+ S + + S +
Sbjct: 30 ASLKSTKSATPNRSLVPTKPATSR----NSVMSPSSSKSTKSTSTKRAPSNRPSSRSRVR 85
Query: 327 EQSRDGSRHPRSHDEDRASHGHSADSSRQSGT--RHAETSSRGQTASSHEQARSS-PGER 383
++R SR +AS ++ GT R RG +S +R+S PG
Sbjct: 86 SKARTPSRVSTDTRTSKASKASDVRCHQRRGTHSRGRTPGRRGSRSSKRSPSRASTPGRI 145
Query: 384 HGSGHQQSADSSRHSATGRGQASSAVSDRGHRGSSGSQASDSEGHSENSDTQSVSGHGKA 443
G + S + T + + S S G +S + SDS+ N +S G +
Sbjct: 146 RTHGARPGMASRVRTPTSQQKGSRGKS-YGRPRTSNRERSDSQ--PRNLSKKSYRPPGGS 202
Query: 444 GLRQQSHQESTRGRSGERSGRSGSSLYQVSTHEQPDSAHGRTGTSTGGRQGSHHEQARDS 503
G+ GRS E + ++ Q T S+ + S+ + S
Sbjct: 203 GI----------GRSSELAVTPSTAKCQTPTGIPSKEKSDNPSPSSSRKVKSYGQMIIPS 252
Query: 504 SRHSASQ-EGQDTIRGHPGSSRGGRQGSHHEQSVNRSGHSGSHHSHTTSQGRSDASHGQS 562
S S E ++ + +S R SH + R SGS T S+ RS S ++
Sbjct: 253 REKSYSPTEMSSRVKSYNQASTRSRPQSHSQSRSPRRSRSGSQ-KRTHSRVRSH-SWKRN 310
Query: 563 GSRSASRQTRNEEQSGDGTRHSGSRHHEASSQADSSRHSQVGQGQSSGPRTSRNQGSSVS 622
SR+ SR TR S G RHS SR H Q QS PR R
Sbjct: 311 HSRARSR-TRKGILSQMG-RHSQSRSHSKGK----------SQNQSRTPRRGR------- 351
Query: 623 QDSDSQGHSEDSERWSGSASRNHHGSAQEQSRDGSRHPRSHHEDRAGHGHSADSSRKSGT 682
S WS + S+ S H RS ++R G S S RK
Sbjct: 352 -----------SHNWSRNPSKERSHS----------HSRSSSKERDHRGSS--SPRKESG 388
Query: 683 RHTQNSSSGQAASSHEQARSSAGERHGSRHQLQSADSSRHSGTGHGQASSAVRDSGHRGS 742
R S + Q S ++ + A +R SR ++ D SR ++ + RD R
Sbjct: 389 RSQSGSPNKQRDHSRSRSPNKARDRSRSRSPYKARDRSR------SRSPNKARDCS-RSR 441
Query: 743 SGSQATDSEGHSEDSDTQSVSGHGQAGHHQQSHQESARDRSGERSRRSGSFLYQVSTHKQ 802
S +A D ++S S + H + ARDRS RS Q+ + +
Sbjct: 442 SPYKARDR--------SRSRSPNKARDHSRSRSPNKARDRSRSRSPSKERDHSQLGSPSK 493
Query: 803 SESSHGWTGPS--TGVRQGSHHEQARDNSR-HSASQDGQDTIRGHPGSSR-RGRQGSHHE 858
PS RQ + RD+ R S S++ Q P R R + S E
Sbjct: 494 ERDHRRSRSPSKERQCRQSRSSSKERDHRRSRSPSKERQRRQSRSPNKERDRSQSRSPSE 553
Query: 859 QSVDRSGHSGSHHSHTTSQGRSDASRGQSGSRSASRTTRNEEQSRDGSRHSGSRHHEASS 918
+ R S S R + SRS+S R+ +SR ++ SG ASS
Sbjct: 554 EREHRQSRSPSKERDRRRWRSPSKERERRQSRSSSE-ERDHSRSRSPNKQSGYSRPRASS 612
Query: 919 HADISRHSQAGQGQSEGSRTSRRQGSSVSQDSDSEGHSEDSERWSGSASRNHRGSAQEQS 978
HS++ EG+ + R S S S S S W S +R S
Sbjct: 613 KE--KAHSRSRTPSKEGNHSQSRTSSKESDPSQST--VPRSPDWKRSPTRTSSLSQNRTP 668
Query: 979 RHGSRHPRSHHEDRAGHGHSADSSRQSGTPHAETSSGGQAASS 1021
S H S G S D S+ T T G +++SS
Sbjct: 669 SKTSSHSPSTFPS-GGQTLSQDDSQADATTSKATLPGERSSSS 710
Score = 91.7 bits (226), Expect = 1e-17
Identities = 175/765 (22%), Positives = 276/765 (36%), Gaps = 108/765 (14%)
Query: 611 PRTSRNQGSSVSQDSDSQGHSEDSERWSGSASRNHHGSAQEQSRDGSRHPRSHHEDRAGH 670
P TSRN SV S S+ S + + S + + ++R SR +A
Sbjct: 49 PATSRN---SVMSPSSSKSTKSTSTKRAPSNRPSSRSRVRSKARTPSRVSTDTRTSKASK 105
Query: 671 GHSADSSRKSGTRHTQNSSSGQAASSHEQARSSAGERHGSRHQLQSADSSRHSGTGHGQA 730
++ GT H++ + G+ S + S G R G G A
Sbjct: 106 ASDVRCHQRRGT-HSRGRTPGRRGSRSSKRSPSRASTPGR---------IRTHGARPGMA 155
Query: 731 SSA----VRDSGHRGSSGSQATDSEGHSEDSDTQSVSGHGQAGHHQQSHQE---SARDRS 783
S + G RG S + S DS +++S ++S++ S RS
Sbjct: 156 SRVRTPTSQQKGSRGKSYGRPRTSNRERSDSQPRNLS--------KKSYRPPGGSGIGRS 207
Query: 784 GERSRRSGSFLYQVSTHKQSESSHGWTGPSTGVRQGSHHEQARDNSRHSASQDGQDT-IR 842
E + + Q T S+ PS+ + S+ + + S S + ++
Sbjct: 208 SELAVTPSTAKCQTPTGIPSKEKSDNPSPSSSRKVKSYGQMIIPSREKSYSPTEMSSRVK 267
Query: 843 GHPGSSRRGRQGSHHEQSVDRSGHSGSHHSHTTSQGRSDASRGQSGSRSASRTTRNEEQS 902
+ +S R R SH + R SGS T S+ RS + + ++ SR+ SRT R S
Sbjct: 268 SYNQASTRSRPQSHSQSRSPRRSRSGSQ-KRTHSRVRSHSWK-RNHSRARSRT-RKGILS 324
Query: 903 RDGSRHSGSRHHEASSHADISRHSQAGQGQSEGSRTSRRQGSSVSQDSDSEGHSEDSERW 962
+ G RHS SR H + SR + G+ + S+ + S S+ S E S
Sbjct: 325 QMG-RHSQSRSHSKGKSQNQSRTPRRGRSHNWSRNPSKERSHSHSRSSSKERDHRGSSSP 383
Query: 963 SGSASRNHRGSAQEQSRHG-SRHP-RSHHEDRAGHGHSADSSRQSGTPHAETSSGGQAAS 1020
+ R+ GS +Q H SR P ++ R+ + A +S +P+ A
Sbjct: 384 RKESGRSQSGSPNKQRDHSRSRSPNKARDRSRSRSPYKARDRSRSRSPN--------KAR 435
Query: 1021 SHEQARSSPGERHGSRHQQSADSSRHSGIPRRQASSAVRDSGHWGSSGSQASDSEGHSEE 1080
++RS R SR + + HS R ++ + RD S S S+E
Sbjct: 436 DCSRSRSPYKARDRSRSRSPNKARDHS---RSRSPNKARD----------RSRSRSPSKE 482
Query: 1081 SDTQSVSGHGQDGPHQQSHQESARDWSGGRSGRSGSFIYQVSTHEQSESAHGRTRTSTGR 1140
D + ++ H++S S R RS S E H R+R+ +
Sbjct: 483 RDHSQLGSPSKERDHRRSRSPSKERQC--RQSRSSS----------KERDHRRSRSPSKE 530
Query: 1141 RQGSHHEQARDSSRHSASQEGQDTIRAHPGSRRGGRQGSHHEQSVDRSGHSGSHHSHTTS 1200
RQ R SR S ++E + P R RQ + DR
Sbjct: 531 RQ-------RRQSR-SPNKERDRSQSRSPSEEREHRQSRSPSKERDRRRWRSPSKERERR 582
Query: 1201 QGRSDASHGQSGSRSASRQTRKDKQSGDGSRHSGSRHHEAASWADSSRHSQVGQEQSSGS 1260
Q RS S R SR +KQSG + S+ ++ S S
Sbjct: 583 QSRS-----SSEERDHSRSRSPNKQSGYSRPRASSK-----------------EKAHSRS 620
Query: 1261 RTSRHQGSSVSQDSDSERHSDDSERLSGSASRNHHGSSREQSRDGSRHPGFHQEDRASHG 1320
RT +G+ SQ S + SD S+ + +R S +R P +
Sbjct: 621 RTPSKEGNH-SQSRTSSKESDPSQSTVPRSPDWKRSPTRTSSLSQNRTPS------KTSS 673
Query: 1321 HSADSSRQSGTHHTESSSHGQAVSSHEQARSSPGERHGSRHQQSA 1365
HS + G ++ S A +S + PGER S + A
Sbjct: 674 HSPSTFPSGGQTLSQDDSQADATTS---KATLPGERSSSSSSKLA 715
Score = 90.9 bits (224), Expect = 2e-17
Identities = 162/764 (21%), Positives = 268/764 (35%), Gaps = 124/764 (16%)
Query: 867 SGSHHSHTTSQGRSDASRGQSGSRSASRTTRNEEQSRDGSRHSGSRHHEASSHADISRHS 926
S S + +TS R+ ++R S SR S+ S D S+ + H HS
Sbjct: 60 SSSKSTKSTSTKRAPSNRPSSRSRVRSKARTPSRVSTDTRTSKASKASDVRCHQRRGTHS 119
Query: 927 QAGQGQSEGSRTSRRQGSSVSQDSDSEGHSEDSERWSGSASRNHRGSAQEQSRHGSRHPR 986
+ GSR+S+R S S H G ASR ++Q++ G +
Sbjct: 120 RGRTPGRRGSRSSKRSPSRASTPGRIRTHGARP----GMASRVRTPTSQQKGSRG----K 171
Query: 987 SHHEDRAGHGHSADSSRQSGTPHAETSSGGQAASSHEQARSSPGERHGSRHQQSADSSRH 1046
S+ R + +DS ++ + + GG + +P +A
Sbjct: 172 SYGRPRTSNRERSDSQPRNLSKKSYRPPGGSGIGRSSELAVTPS---------TAKCQTP 222
Query: 1047 SGIPRRQASSAVRDSGHWGSSGSQASDSEGHSEESDTQSVSGHGQDGPHQQSHQESARDW 1106
+GIP ++ S + S ++ V +GQ + S +
Sbjct: 223 TGIPSKEKSD--------------------NPSPSSSRKVKSYGQMIIPSREKSYSPTEM 262
Query: 1107 SGGRSGRSGSFIYQVSTHEQSESAHGRTRTSTGRRQGSHHEQARDSSRHSASQEGQDTIR 1166
S R S+ Q ST + +S H ++R+ R GS Q R SR +R
Sbjct: 263 SS----RVKSY-NQASTRSRPQS-HSQSRSPRRSRSGS---QKRTHSR----------VR 303
Query: 1167 AHPGSRRGGRQGSHHEQSVDRSGHSGSHHSHTTSQGRSDASHGQSGSRSASRQTRKDKQS 1226
+H R R S + + G H SQ RS H + S++ SR R+
Sbjct: 304 SHSWKRNHSRARSRTRKGI--LSQMGRH-----SQSRS---HSKGKSQNQSRTPRR---- 349
Query: 1227 GDGSRHSGSRHHEAASWADSSRHSQVGQEQSSGSRTSRHQGSSVSQDSDSERHSDDSERL 1286
G H+ SR+ S S HS+ S S+ H+GSS + S +
Sbjct: 350 --GRSHNWSRN---PSKERSHSHSR------SSSKERDHRGSSSPRKESGRSQSGSPNKQ 398
Query: 1287 SGSASRNHHGSSREQSRDGSRHPGFHQEDRASHGHSADSSRQSGTHHTESSSHGQA---V 1343
+ +R++SR S + + S + D SR + S ++
Sbjct: 399 RDHSRSRSPNKARDRSRSRSPYKARDRSRSRSPNKARDCSRSRSPYKARDRSRSRSPNKA 458
Query: 1344 SSHEQARSSPGERHGSRHQQSADSSRHSGIGHRQASSAVRDSGHRGSSGSQVTNSEGHSE 1403
H ++RS R SR + + HS +G S ++ HR S S+
Sbjct: 459 RDHSRSRSPNKARDRSRSRSPSKERDHSQLG-----SPSKERDHR--------RSRSPSK 505
Query: 1404 DSDTQSVSAHGQAGPHQQSHKESARGQSGESSGRSRSFLYQVSSHEQSESTHGQTAPSTG 1463
+ + + + H++S S Q +S ++ S E H Q+ +
Sbjct: 506 ERQCRQSRSSSKERDHRRSRSPSKERQRRQSRSPNKERDRSQSRSPSEEREHRQSRSPSK 565
Query: 1464 GRQGSR-----HEQARNSSRHSASQDGQDTIRGHPGSSRGGRQGSYHEQSVDRSGHSGYH 1518
R R E+ R SR S+ + R H S +Q Y S H
Sbjct: 566 ERDRRRWRSPSKERERRQSRSSSEE------RDHSRSRSPNKQSGYSRPRA--SSKEKAH 617
Query: 1519 HSHTTPQGRSDASHGQSGPRSASRQTRNEEQSGDGSRHSGSRHHEPSTRAGSSRHSQVGQ 1578
TP + S ++ + + +S D R P+ + S++ +
Sbjct: 618 SRSRTPSKEGNHSQSRTSSKESDPSQSTVPRSPDWKR-------SPTRTSSLSQNRTPSK 670
Query: 1579 GESAGSKTSRRQGSSVSQDRDSEGHSEDS------ERRSESASR 1616
S T G ++SQD DS+ + S ER S S+S+
Sbjct: 671 TSSHSPSTFPSGGQTLSQD-DSQADATTSKATLPGERSSSSSSK 713
Score = 90.1 bits (222), Expect = 4e-17
Identities = 149/703 (21%), Positives = 243/703 (34%), Gaps = 73/703 (10%)
Query: 1268 SSVSQDSDSERHSDDSERLSGSASRNHHGSSREQSRDGSRHPGFHQEDRASHGHSADSSR 1327
+SV S S+ S + + S + R ++R SR + +AS +
Sbjct: 54 NSVMSPSSSKSTKSTSTKRAPSNRPSSRSRVRSKARTPSRVSTDTRTSKASKASDVRCHQ 113
Query: 1328 QSGTHHTESSS--HGQAVSSHEQARSS-PGE--RHGSRHQQSADSSRHSGIGHRQASSAV 1382
+ GTH + G S +R+S PG HG+R G+ R +
Sbjct: 114 RRGTHSRGRTPGRRGSRSSKRSPSRASTPGRIRTHGAR----------PGMASRVRTPTS 163
Query: 1383 RDSGHRGSSGSQVTNSEGHSEDSDTQSVSAHGQAGPHQQSHKESARGQSGESSGRSRSFL 1442
+ G RG S + S DS +++S K+S R G GRS
Sbjct: 164 QQKGSRGKSYGRPRTSNRERSDSQPRNLS------------KKSYRPPGGSGIGRSSELA 211
Query: 1443 YQVSSHEQSESTHGQTAPSTGGRQGSRHEQARNSSRHSASQDGQDTI----RGHPGSSRG 1498
S+ + TG + + SS GQ I + + +
Sbjct: 212 VTPST--------AKCQTPTGIPSKEKSDNPSPSSSRKVKSYGQMIIPSREKSYSPTEMS 263
Query: 1499 GRQGSYHEQSVDRSGHSGYHHSHTTPQGRSDA---------SHGQSGPRSASRQTRNEEQ 1549
R SY++ S RS + S + + RS + SH S +R +
Sbjct: 264 SRVKSYNQAST-RSRPQSHSQSRSPRRSRSGSQKRTHSRVRSHSWKRNHSRARSRTRKGI 322
Query: 1550 SGDGSRHSGSRHHEPSTRAGSSRHSQVGQGESAGSKTSRRQGSSVSQDRDSEGHSEDSER 1609
RHS SR H SR + G+ + S+ + S S+ E S
Sbjct: 323 LSQMGRHSQSRSHSKGKSQNQSRTPRRGRSHNWSRNPSKERSHSHSRSSSKERDHRGSSS 382
Query: 1610 RSESASRNHYGSAREQSRHG-SRNP---RSHQEDRASHGHSAESSRQSGTRHAETSSGGQ 1665
+ + R+ GS +Q H SR+P R R+ + S +S + + S
Sbjct: 383 PRKESGRSQSGSPNKQRDHSRSRSPNKARDRSRSRSPYKARDRSRSRSPNKARDCSRSRS 442
Query: 1666 AASSQEQARS-SPGERHGSRHQQSADSSTDSGTGRRQDSSVVGDSGNRGSSGSQASDSEG 1724
+++++RS SP + +S + + D R + S D GS +
Sbjct: 443 PYKARDRSRSRSPNKARDHSRSRSPNKARD--RSRSRSPSKERDHSQLGSPSKERDHRRS 500
Query: 1725 HSEESDTQSVSAHGQAGPHQQSHQESTRGQSGERSGRSGSFLYQVSTHEQSESAHGRTGP 1784
S + Q ++ ++ H+ S R S ER R + QS S P
Sbjct: 501 RSPSKERQ--CRQSRSSSKERDHRRS-RSPSKERQRRQSRSPNKERDRSQSRS------P 551
Query: 1785 STGGRQRSRHEQARDSSRHSASQEGQDTIRGHPGSSRGGRQGSHYEQSVDSSGHSGSHHS 1844
S R +++ R ++ R SS R S SG+S S
Sbjct: 552 SEEREHRQSRSPSKERDRRRWRSPSKERERRQSRSSSEERDHSRSRSPNKQSGYSRPRAS 611
Query: 1845 HTTSQERSDVSRGQSGSRSVSRQTRNEKQSGDGSRHSGSRHHEASSRADS-SRHSQVGQG 1903
+ + G+ S SR + E + + +R S S++ +
Sbjct: 612 SKEKAHSRSRTPSKEGNHSQSRTSSKESDPSQSTVPRSPDWKRSPTRTSSLSQNRTPSKT 671
Query: 1904 QSSGPRTSRNQGSSVSQDSDSQGHSEDS------ERWSGSASR 1940
S P T + G ++SQD DSQ + S ER S S+S+
Sbjct: 672 SSHSPSTFPSGGQTLSQD-DSQADATTSKATLPGERSSSSSSK 713
Score = 89.7 bits (221), Expect = 5e-17
Identities = 169/709 (23%), Positives = 264/709 (37%), Gaps = 84/709 (11%)
Query: 1592 SSVSQDRDSEGHSEDSERRSESASRNHYGSAREQSRHGSRNPRSHQEDRASHGHSAESSR 1651
+SV S+ S +R+ S + R ++R SR + +AS +
Sbjct: 54 NSVMSPSSSKSTKSTSTKRAPSNRPSSRSRVRSKARTPSRVSTDTRTSKASKASDVRCHQ 113
Query: 1652 QSGTRHAETSSGGQAASSQEQA---RSSPGE--RHGSRHQQSADSSTDSGTGRRQDSSVV 1706
+ GT + G + + S +++ S+PG HG+R G R +
Sbjct: 114 RRGTHSRGRTPGRRGSRSSKRSPSRASTPGRIRTHGAR----------PGMASRVRTPTS 163
Query: 1707 GDSGNRGSSGSQASDSEGHSEESDTQSVSAHGQAGPHQQSHQESTRGQSGERSGRSGSFL 1766
G+RG S + S +S +++S P S G+S E + +
Sbjct: 164 QQKGSRGKSYGRPRTSNRERSDSQPRNLSKKSYRPPGG-----SGIGRSSELAVTPSTAK 218
Query: 1767 YQVSTHEQSESAHGRTGPSTGGRQRSRHEQARDSSRHSASQ-EGQDTIRGHPGSSRGGRQ 1825
Q T S+ PS+ + +S + S S S E ++ + +S R
Sbjct: 219 CQTPTGIPSKEKSDNPSPSSSRKVKSYGQMIIPSREKSYSPTEMSSRVKSYNQASTRSRP 278
Query: 1826 GSHYEQSVDSSGHSGSHHSHTTSQERSDVSRGQSGSRSVSRQTRNEKQSGDGSRHSGSRH 1885
SH + SGS T S+ RS S ++ SR+ SR TR S G RHS SR
Sbjct: 279 QSHSQSRSPRRSRSGSQ-KRTHSRVRSH-SWKRNHSRARSR-TRKGILSQMG-RHSQSRS 334
Query: 1886 HEASSRADSSRHSQVGQGQSSGPRTSRNQGSSVSQDSD-SQGHSEDSERWSGSASRNHLG 1944
H Q QS PR R+ S + + S HS S S R+H G
Sbjct: 335 HSKGK----------SQNQSRTPRRGRSHNWSRNPSKERSHSHSR-----SSSKERDHRG 379
Query: 1945 SAWEQSRDGSRHPGSHHEDRAGHGHSADSSRQSGTRHTESSSRGQAAS-SHEQARSSAGE 2003
S+ + G GS ++ R HS S + S S +A S ++ + A +
Sbjct: 380 SSSPRKESGRSQSGSPNKQR---DHSRSRSPNKARDRSRSRSPYKARDRSRSRSPNKARD 436
Query: 2004 RHGSHHQLQSADSSRHSGIGHGQASSAVRDSGHRGYSGSQASD---SEGHSEDSDTQSVS 2060
S ++ D SR ++ + RD R S ++A D S S++ D +
Sbjct: 437 CSRSRSPYKARDRSR------SRSPNKARDHS-RSRSPNKARDRSRSRSPSKERDHSQLG 489
Query: 2061 AQGKAGPHQQSHKESARGQSGESSGRSGSFLYQVSTHEQSESTHGQSAPSTGGRQGSHYD 2120
+ K H++S S Q +S S ++ S E QS R S
Sbjct: 490 SPSKERDHRRSRSPSKERQCRQSRSSSKERDHRRSRSPSKERQRRQSRSPNKERDRSQSR 549
Query: 2121 QAQDSSRH----SASQEGQDTIRGHPGPSRGGRQGSHQEQSVDRSGHSGSHHSHTTSQGR 2176
+ H S S+E P R RQ + D S + S+ R
Sbjct: 550 SPSEEREHRQSRSPSKERDRRRWRSPSKERERRQSRSSSEERDHSRSRSPNKQSGYSRPR 609
Query: 2177 SDASRGQSGSRSASRKTYDKEQSGDGSRHSGSHHHEASS-------WADS-SRHSLVGQG 2228
+ +S+ ++ SRS +T KE + SR S + S W S +R S + Q
Sbjct: 610 A-SSKEKAHSRS---RTPSKEGNHSQSRTSSKESDPSQSTVPRSPDWKRSPTRTSSLSQN 665
Query: 2229 Q------SSGPRTSRPRGSSVSQDSDSEGHSEDS------ERRSGSASR 2265
+ S P T G ++SQD DS+ + S ER S S+S+
Sbjct: 666 RTPSKTSSHSPSTFPSGGQTLSQD-DSQADATTSKATLPGERSSSSSSK 713
Score = 85.5 bits (210), Expect = 1e-15
Identities = 154/687 (22%), Positives = 250/687 (36%), Gaps = 78/687 (11%)
Query: 117 ENKENRKRPSSLERRNNRKGNKGRSKSPRETGGKRHESSSEKKERKGYSPTHREEEYGKN 176
+ + ++ +S R + R+G R ++P G + + S + G TH +
Sbjct: 97 DTRTSKASKASDVRCHQRRGTHSRGRTPGRRGSRSSKRSPSRASTPGRIRTHGARPGMAS 156
Query: 177 HHNSSKKEKNKTENTRLGDNRKRLSERLEEKEDNEEGVYDYENTGRMTQKWIQSGHIATY 236
+ ++ + G R ER + + N +++K + +
Sbjct: 157 RVRTPTSQQKGSRGKSYGRPRTSNRERSDSQPRN------------LSKKSYRPPGGSGI 204
Query: 237 YTIQDEAYDTTDSLLEENKIYERSRSSDGKSSSQVNRSRHENTSQVPLQE-SRTRKRRGS 295
+ A + + + SD S S + + +P +E S + S
Sbjct: 205 GRSSELAVTPSTAKCQTPTGIPSKEKSDNPSPSSSRKVKSYGQMIIPSREKSYSPTEMSS 264
Query: 296 RV-SQDRDSEGHSEDSERHSGSASRNHHGSAWEQSRDGSRHPRSHDEDRASHGHSADSSR 354
RV S ++ S S S S R+ GS Q R SR RSH R +H + +R
Sbjct: 265 RVKSYNQASTRSRPQSHSQSRSPRRSRSGS---QKRTHSR-VRSHSWKR-NHSRARSRTR 319
Query: 355 QSGTRHAETSSRGQTASSHEQARSSPGERHGSGHQQSADSSRHSATGRGQASSAVSDRGH 414
+ S+ ++ S + S R G H S + S+ + ++SS +R H
Sbjct: 320 KGILSQMGRHSQSRSHSKGKSQNQSRTPRRGRSHNWSRNPSKERSHSHSRSSS--KERDH 377
Query: 415 RGSSGSQASDSEGHSENSDTQSVSGHGKAGLRQQSHQESTRGRSGERSGRSGSSLYQVST 474
RGSS + E+ +QS S + +Q+ H S RS + S
Sbjct: 378 RGSSSPR-------KESGRSQSGSPN-----KQRDHSRS----------RSPNKARDRSR 415
Query: 475 HEQPDSAHGRTGTSTGGRQGSHHEQARDSSRHSASQEGQDTIRGHPGSSRGGRQGSHHEQ 534
P A R+ + + + ARD SR + + +D R SR + H +
Sbjct: 416 SRSPYKARDRSRSRSPNK-------ARDCSRSRSPYKARDRSR-----SRSPNKARDHSR 463
Query: 535 SVNRSGHSGSHHSHTTSQGRSDASHGQSGSRSASRQTRNEEQSGDGTRHSGSRHHEASSQ 594
S RS + S + S + + H Q GS S R R S S+ +
Sbjct: 464 S--RSPNKARDRSRSRSPSK-ERDHSQLGSPSKERDHRRS--------RSPSKERQCRQS 512
Query: 595 ADSSRHSQVGQGQSSGPRTSRNQGSSVSQDSD-SQGHSEDSERWSGSASRNHHGSAQEQS 653
SS+ + +S R Q S +++ D SQ S ER R ++E+
Sbjct: 513 RSSSKERDHRRSRSPSKERQRRQSRSPNKERDRSQSRSPSEER----EHRQSRSPSKERD 568
Query: 654 RDGSRHPRSHHEDRAGHGHSADSSR-KSGTRHTQNSSSGQAASSHEQARSSAGERHGSRH 712
R R P E R S + +S + + Q+ S ASS E+A S + +
Sbjct: 569 RRRWRSPSKERERRQSRSSSEERDHSRSRSPNKQSGYSRPRASSKEKAHSRSRTPSKEGN 628
Query: 713 QLQSADSSRHSGTGHGQA--SSAVRDSGHRGSSGSQATDSEGHSEDSDTQSVSGHGQAGH 770
QS SS+ S S + S R SS SQ S S + SG GQ
Sbjct: 629 HSQSRTSSKESDPSQSTVPRSPDWKRSPTRTSSLSQNRTPSKTSSHSPSTFPSG-GQTLS 687
Query: 771 HQQSHQESARDRS---GERSRRSGSFL 794
S ++ ++ GERS S S L
Sbjct: 688 QDDSQADATTSKATLPGERSSSSSSKL 714
Score = 85.1 bits (209), Expect = 1e-15
Identities = 148/678 (21%), Positives = 244/678 (35%), Gaps = 73/678 (10%)
Query: 2889 SSVSQDSDSEGHSEDSERWSGSASRNHHGSAQEQLRDGSRHPRSHQEDRAGHGHSADSSR 2948
+SV S S+ S + + S + + + R SR + +A +
Sbjct: 54 NSVMSPSSSKSTKSTSTKRAPSNRPSSRSRVRSKARTPSRVSTDTRTSKASKASDVRCHQ 113
Query: 2949 QSGTRHTQTSSG--GQAASSHEQARSSAGERHGSHHQQSADSSRHSGIGHGQASSAVRDS 3006
+ GT + G G +S +R+S R +H + +SR + +
Sbjct: 114 RRGTHSRGRTPGRRGSRSSKRSPSRASTPGRIRTHGARPGMASR-------VRTPTSQQK 166
Query: 3007 GHRGYSGSQASDNEGHSEDSDTQSVSAHGQAGSHQQSHQESARGRSGETSGHSGSFLYQV 3066
G RG S + + DS +++S + S GRS E + + Q
Sbjct: 167 GSRGKSYGRPRTSNRERSDSQPRNLSKKSY-----RPPGGSGIGRSSELAVTPSTAKCQT 221
Query: 3067 STHEQSESSHGWTGPSTRGRQGSRHEQAQDSSRHSASQYGQDT-IRGHPGSSRGGRQGYH 3125
T S+ PS+ + S + S S S + ++ + +S R H
Sbjct: 222 PTGIPSKEKSDNPSPSSSRKVKSYGQMIIPSREKSYSPTEMSSRVKSYNQASTRSRPQSH 281
Query: 3126 HEHSVDSSGHSGSHHSHTTSQGRSDASRGQSGSRSASRTTRNEEQSGDSSRHSVSRHHEA 3185
+ SGS T S+ RS + + ++ SR+ SRT + RHS SR H
Sbjct: 282 SQSRSPRRSRSGSQ-KRTHSRVRSHSWK-RNHSRARSRTRKGI--LSQMGRHSQSRSHS- 336
Query: 3186 STHADISRHSQAVQGQSEGSRRSRRQGSSVSQDSDSEGHSEDSERWSGSASRNHRGSVQE 3245
+G+S+ R+ R+G S + + S S S R+HRGS
Sbjct: 337 -------------KGKSQNQSRTPRRGRSHNWSRNPSKERSHSHSRSSSKERDHRGSSSP 383
Query: 3246 -----QSRHGSRHPRSHHEDRAGHGHSADRSRQSG---TRHAETSSGGQAASSHEQARSS 3297
+S+ GS + + H + DRSR R S A ++RS
Sbjct: 384 RKESGRSQSGSPNKQRDHSRSRSPNKARDRSRSRSPYKARDRSRSRSPNKARDCSRSRSP 443
Query: 3298 PGERHGSRHQQSADSSRHSGIPRGQASSAVRDSRHWGSSGSQASDSEGHSEESDTQSVSG 3357
R SR + + HS R ++ + RD S S S+E D +
Sbjct: 444 YKARDRSRSRSPNKARDHS---RSRSPNKARD----------RSRSRSPSKERDHSQLGS 490
Query: 3358 HGQAGPHQQSHQESARDRSGGRSGRSGSFLYQVSTHEQSESAHGRTRTST---GRRQGSH 3414
+ H++S S + R RS S E H R+R+ + RRQ
Sbjct: 491 PSKERDHRRSRSPSKERQC--RQSRSSS----------KERDHRRSRSPSKERQRRQSRS 538
Query: 3415 HEQARDSSRHSASQEGQDTIRGHPGSSRRGRQGSHYEQSVDRSGHSGSHHSHTTSQGRSD 3474
+ RD S+ + E ++ + S R R+ S +R S RS
Sbjct: 539 PNKERDRSQSRSPSEEREHRQSRSPSKERDRR-RWRSPSKERERRQSRSSSEERDHSRSR 597
Query: 3475 ASRGQSGSRSASRQTRNDEQSGDGSRHSWSHHHEASTQADSSRHSQSGQGQSAGPRTSRN 3534
+ QSG ++ S + +H ++ T + S SQS +S + S
Sbjct: 598 SPNKQSGYSRPRASSKEKAHSRSRTPSKEGNHSQSRTSSKESDPSQSTVPRSPDWKRSPT 657
Query: 3535 QGSSVSQD---SDSQGHS 3549
+ SS+SQ+ S + HS
Sbjct: 658 RTSSLSQNRTPSKTSSHS 675
Score = 72.0 bits (175), Expect = 1e-11
Identities = 139/679 (20%), Positives = 241/679 (35%), Gaps = 62/679 (9%)
Query: 2557 PRTSRNWGSSFSQDSDSQGHSEDSERWSGSASRNHHGSAQEQLRDGSRHPRSHQEDRAGH 2616
P TSRN S S S+ S + + S + + + R SR + +A
Sbjct: 49 PATSRN---SVMSPSSSKSTKSTSTKRAPSNRPSSRSRVRSKARTPSRVSTDTRTSKASK 105
Query: 2617 GHSADSSRQSGTRHTQTSSG--GQAASSHEQARSSAGERHGSHHQQSADSSRHSGIGHGQ 2674
++ GT + G G +S +R+S R +H + +SR
Sbjct: 106 ASDVRCHQRRGTHSRGRTPGRRGSRSSKRSPSRASTPGRIRTHGARPGMASR-------V 158
Query: 2675 ASSAVRDSGHRGYSGSQASDNEGHSEDSDTQSVSAHGQAGSHQQSHQESARGRSGETSGH 2734
+ + G RG S + + DS +++S + S GRS E +
Sbjct: 159 RTPTSQQKGSRGKSYGRPRTSNRERSDSQPRNLSKKSY-----RPPGGSGIGRSSELAVT 213
Query: 2735 SGSFLYQVSTHEQSESSHGWTGPSTRGRQGSRHEQAQDSSRHSASQDGQDT-IRGHPGSS 2793
+ Q T S+ PS+ + S + S S S + ++ + +S
Sbjct: 214 PSTAKCQTPTGIPSKEKSDNPSPSSSRKVKSYGQMIIPSREKSYSPTEMSSRVKSYNQAS 273
Query: 2794 RGGRQGYHHEHSVDSSGHSGSHHSHTTSQGRSDASRGQSGSRSASRTTRNE-EQSGDGSR 2852
R H + SGS T S+ RS + + ++ SR+ SRT + Q G R
Sbjct: 274 TRSRPQSHSQSRSPRRSRSGSQ-KRTHSRVRSHSWK-RNHSRARSRTRKGILSQMG---R 328
Query: 2853 HSGSRHHEASTHADISRHSQAVQGQSEGSRRSRRQGSSVSQDSDSEGHSEDSERWSGSAS 2912
HS SR H +G+S+ R+ R+G S + + S S S
Sbjct: 329 HSQSRSHS--------------KGKSQNQSRTPRRGRSHNWSRNPSKERSHSHSRSSSKE 374
Query: 2913 RNHHGSAQEQLRDGSRHPRSHQEDRAGHGHSADSSRQSGTRHTQTSSGGQAASSHEQARS 2972
R+H GS+ + G S + R H S ++ R S A ++RS
Sbjct: 375 RDHRGSSSPRKESGRSQSGSPNKQR-DHSRSRSPNK---ARDRSRSRSPYKARDRSRSRS 430
Query: 2973 SAGERHGSHHQQSADSSRHSGIGHGQASSAVRDSGHRGYSGSQASD---NEGHSEDSDTQ 3029
R S + + S ++ + RD R S ++A D + S++ D
Sbjct: 431 PNKARDCSRSRSPYKARDRS---RSRSPNKARDHS-RSRSPNKARDRSRSRSPSKERDHS 486
Query: 3030 SVSAHGQAGSHQQSHQESARGRSGETSGHSGSFLYQVSTHEQSESSHGWTGPSTRGRQGS 3089
+ + + H++S S + ++ S ++ S E + + R S
Sbjct: 487 QLGSPSKERDHRRSRSPSKERQCRQSRSSSKERDHRRSRSPSKERQRRQSRSPNKERDRS 546
Query: 3090 RHEQAQDSSRHSASQYGQDTIRGHPGSSRGGRQGYHHEHSVDSSGHSGSHHSHTTSQGRS 3149
+ + H S+ P R R+ S + S RS
Sbjct: 547 QSRSPSEEREHRQSR--------SPSKERDRRR--WRSPSKERERRQSRSSSEERDHSRS 596
Query: 3150 DASRGQSGSRSASRTTRNEEQSGDSSRHSVSRHHEASTHADISRHSQAVQGQSEGSRRSR 3209
+ QSG +++ + S + H ++ T + S SQ+ +S +RS
Sbjct: 597 RSPNKQSGYSRPRASSKEKAHSRSRTPSKEGNHSQSRTSSKESDPSQSTVPRSPDWKRSP 656
Query: 3210 RQGSSVSQD---SDSEGHS 3225
+ SS+SQ+ S + HS
Sbjct: 657 TRTSSLSQNRTPSKTSSHS 675
Score = 68.9 bits (167), Expect = 9e-11
Identities = 116/508 (22%), Positives = 193/508 (37%), Gaps = 73/508 (14%)
Query: 88 STRKENLPISGHKHRKHSHHDKHEDNKQEENKENRKRPSSLERRNNRKGNKGRSKSPRET 147
S+R ++ + + R SH + + R R ++ RS++ +
Sbjct: 263 SSRVKSYNQASTRSRPQSHSQSRSPRRSRSGSQKRTHSRVRSHSWKRNHSRARSRTRKGI 322
Query: 148 GGKRHESSSEKKERKGYSPTH-REEEYGKNHHNSSKKEKNKTENTRLGDNRKRLSERLEE 206
+ S + KG S R G++H+ S K ++ + +++R
Sbjct: 323 LSQMGRHSQSRSHSKGKSQNQSRTPRRGRSHNWSRNPSKERSHSHSRSSSKER------- 375
Query: 207 KEDNEEGVYDYENTGRMTQKWIQSGHIATYYTIQDEAYDTTDSLLEENKIYERSRSSDGK 266
D+ + +GR QSG ++ D + S NK +RSRS
Sbjct: 376 --DHRGSSSPRKESGRS-----QSGS-------PNKQRDHSRS-RSPNKARDRSRSRSPY 420
Query: 267 SSSQVNRSRHENTSQVPLQESRTRKRRGSRVSQDRDSEGHSEDSERHSGSASRNHHGSAW 326
+ +RSR N ++ SR+R +R DR + HS S S N
Sbjct: 421 KARDRSRSRSPNKAR---DCSRSRSPYKAR---DRSRSRSPNKARDHSRSRSPNK----- 469
Query: 327 EQSRDGSRHP---RSHDE-----DRASHGHSADSSRQSGTRHAETSSRGQTASSHEQARS 378
+ R SR P R H + H S S++ R + +SS+ + H ++RS
Sbjct: 470 ARDRSRSRSPSKERDHSQLGSPSKERDHRRSRSPSKERQCRQSRSSSKER---DHRRSRS 526
Query: 379 SPGERHGSGHQQSADSSRHSATGRGQASSAVSDRGHRGSSGSQASDSEGHSENSDTQSVS 438
ER Q+ S + R Q+ S +R HR S S+ D +
Sbjct: 527 PSKER-----QRRQSRSPNKERDRSQSRSPSEEREHR--------QSRSPSKERDRRRWR 573
Query: 439 GHGKAGLRQQSH---QESTRGRSGERSGRSGSSLYQVSTHEQPDSAHGRTGTSTGGRQGS 495
K R+QS +E RS + +SG S + S+ E+ AH R+ T + +
Sbjct: 574 SPSKERERRQSRSSSEERDHSRSRSPNKQSGYSRPRASSKEK---AHSRSRTPS---KEG 627
Query: 496 HHEQARDSSRHSASQEGQDTIRGHPGSSRGGRQGSHHEQSVNRSGHSGSHHSHTT--SQG 553
+H Q+R SS+ S Q T+ P R + S Q NR+ S HS +T S G
Sbjct: 628 NHSQSRTSSKE--SDPSQSTVPRSPDWKRSPTRTSSLSQ--NRTPSKTSSHSPSTFPSGG 683
Query: 554 RSDASHGQSGSRSASRQTRNEEQSGDGT 581
++ + + S+ T E+S +
Sbjct: 684 QTLSQDDSQADATTSKATLPGERSSSSS 711
>gi|153251865 hypothetical protein LOC84226 [Homo sapiens]
Length = 1984
Score = 95.9 bits (237), Expect = 7e-19
Identities = 146/584 (25%), Positives = 211/584 (36%), Gaps = 127/584 (21%)
Query: 686 QNSSSGQAASSHEQARSSAGERHGSRHQLQSADS-------SRHSGTGHGQASSAVRDSG 738
Q +S GQ + ++ SS +++ R++ S +S +R G S V+ +
Sbjct: 1467 QTASVGQPLRTVQKDSSSRSKKNFYRNETSSQESKNLSTPGTRVQARGRILPGSPVKRTW 1526
Query: 739 HRGSSGSQATDSEGHSEDSDTQSVSGHGQAGHHQQSHQESARDRS----GERSRRSGSFL 794
HR H +D T H + +H R+R+ ER+R + S+
Sbjct: 1527 HR------------HLKDKLT----------HKEHNHPSFYRERTPRGPSERTRHNPSWR 1564
Query: 795 YQVSTHKQSESSHGWTGPSTGVRQGSHHEQARDNSRHSASQDGQDTIRGHPGSSRRGRQG 854
S ++S+ S + + HS SQ R H SR+
Sbjct: 1565 NHRSPSERSQRS------------------SLERRHHSPSQ------RSHCSPSRK---- 1596
Query: 855 SHHEQSVDRSGHSGSHHSHTTSQGRSDASRGQSGSRSASRTT-------RNEEQSRDGSR 907
+H +RS S S +H + RS S + G S S+ + R+ S R
Sbjct: 1597 -NHSSPSERSWRSPSQRNHCSPPERSCHSLSERGLHSPSQRSHRGPSQRRHHSPSERSHR 1655
Query: 908 HSGSRHHEASS---HADISRHSQAGQGQSEGSRTSRRQGSSVSQDSDSEGHSEDSERWSG 964
R H +SS H S+ S G + S R+ S SQ S H SER
Sbjct: 1656 SPSERSHRSSSERRHRSPSQRSHRGPSERSHCSPSERRHRSPSQRS----HRGPSERRHH 1711
Query: 965 SAS-RNHRGSAQEQSRHGSRHPRSHHEDRAGHGHSADSSRQ---SGTPHAETSSGGQAAS 1020
S S R+HR A+ H S RSHH HS R S H S +
Sbjct: 1712 SPSKRSHRSPARRS--HRSPSERSHHSPSERSHHSPSERRHHSPSERSHCSPSERSHCSP 1769
Query: 1021 SHEQARSSPGERHGS----RHQQSADSSRHSGIPRRQASSAVRDSGHWGSSGSQASDSEG 1076
S + RS RH S H ++ S HS RR+ S R S H S S SE
Sbjct: 1770 SERRHRSPSERRHHSPSEKSHHSPSERSHHSPSERRRHSPLER-SRHSLLERSHRSPSER 1828
Query: 1077 HSEESDTQSVSGHGQDGPHQQSHQESARDWSGGRSGRSGSFIYQVSTHEQSESAH----G 1132
S S +S H++ + S H SE +H
Sbjct: 1829 RSHRSFERS---------HRRISERS---------------------HSPSEKSHLSPLE 1858
Query: 1133 RTRTSTGRRQGSHHEQARDSSRHSASQEGQDTIRAHPGSRRGGRQGSHHEQSVDRSGHSG 1192
R+R S R+G + + HS S+ R+ G R+G H S +R+ HS
Sbjct: 1859 RSRCSPSERRG---HSSSGKTCHSPSERSH---RSPSGMRQGRTSERSHRSSCERTRHSP 1912
Query: 1193 SHHSHTTSQGRSDASHGQSGSRSASRQTRKDKQSGDGSRHSGSR 1236
S GR+ S + RS ++ K G+ HS SR
Sbjct: 1913 SEMRPGRPSGRNHCSPSERSRRSPLKEGLKYSFPGERPSHSLSR 1956
Score = 95.5 bits (236), Expect = 9e-19
Identities = 110/465 (23%), Positives = 172/465 (36%), Gaps = 30/465 (6%)
Query: 1123 TH-EQSESAHGRTRTSTGRRQGSHHEQARDSSRHSASQEGQDTI--RAHPGSRRGGRQGS 1179
TH E + + R RT G + + H + + R + + + ++ R H S+R S
Sbjct: 1535 THKEHNHPSFYRERTPRGPSERTRHNPSWRNHRSPSERSQRSSLERRHHSPSQRSHCSPS 1594
Query: 1180 --HHEQSVDRSGHSGSHHSHTTSQGRSDASHGQSGSRSASRQTRKDKQSGDGSRHSGSRH 1237
+H +RS S S +H + RS S + G S S+++ + RH
Sbjct: 1595 RKNHSSPSERSWRSPSQRNHCSPPERSCHSLSERGLHSPSQRSHRGPSQ---RRHHSPSE 1651
Query: 1238 HEAASWADSSRHSQVGQEQSSGSRTSRHQGSSVSQDSDSER-HSDDSERLS-GSASRNHH 1295
S ++ S S + S S+ S S S S SER H S+R G + R HH
Sbjct: 1652 RSHRSPSERSHRSSSERRHRSPSQRSHRGPSERSHCSPSERRHRSPSQRSHRGPSERRHH 1711
Query: 1296 GSSREQSRDGSRHPGFHQEDRASHGHSADSSRQSGTHHTESSSHGQAVSSHEQARSSPGE 1355
S+ R +R +R+ H S S S S S E++ SP E
Sbjct: 1712 SPSKRSHRSPARRSHRSPSERSHHSPSERSHHSPSERRHHSPSERSHCSPSERSHCSPSE 1771
Query: 1356 RHGSRHQQSADSSRHSGIGHRQASSAVRDSGHRGSSGSQVTNSEGHSEDSDTQSVSAHGQ 1415
R RH R+ S S H S S + SE +S +
Sbjct: 1772 R------------RHRSPSERRHHSPSEKSHHSPSERSHHSPSERRRHSPLERS-----R 1814
Query: 1416 AGPHQQSHKESARGQSGESSGRSRSFLYQVSSHEQSESTHGQTAPSTGGRQGSRHEQARN 1475
++SH+ + +S S RS + + SH SE +H +P R + +
Sbjct: 1815 HSLLERSHRSPSERRSHRSFERSHRRISE-RSHSPSEKSH--LSPLERSRCSPSERRGHS 1871
Query: 1476 SSRHSASQDGQDTIRGHPGSSRGGRQGSYHEQSVDRSGHSGYHHSHTTPQGRSDASHGQS 1535
SS + + + R G +G H S +R+ HS P GR+ S +
Sbjct: 1872 SSGKTCHSPSERSHRSPSGMRQGRTSERSHRSSCERTRHSPSEMRPGRPSGRNHCSPSER 1931
Query: 1536 GPRSASRQTRNEEQSGDGSRHSGSRHHEPSTRAGSSRHSQVGQGE 1580
RS ++ G+ HS SR + T + H G+
Sbjct: 1932 SRRSPLKEGLKYSFPGERPSHSLSRDFKNQTTLLGTTHKNPKAGQ 1976
Score = 90.9 bits (224), Expect = 2e-17
Identities = 152/648 (23%), Positives = 218/648 (33%), Gaps = 113/648 (17%)
Query: 2907 WSGSASRNHHGSAQEQLRDGSRHPRSHQEDRAGHGHSADSSRQSGTRHTQTSSGGQAASS 2966
W G+ SAQ+ R S PR + + + QSG QT+S GQ +
Sbjct: 1429 WGGTVQCR---SAQQPRRAYSFQPRPLRLPKP-------TDSQSGIAF-QTASVGQPLRT 1477
Query: 2967 HEQARSSAGERHGSHHQQSADSSRHSGI--------GHGQASSAVRDSGHRGYSGSQASD 3018
++ SS +++ ++ S+ S++ G S V+ + HR
Sbjct: 1478 VQKDSSSRSKKNFYRNETSSQESKNLSTPGTRVQARGRILPGSPVKRTWHRHLKDKLTHK 1537
Query: 3019 NEGHSE------DSDTQSVSAHGQAGSHQQSHQESARGRSGETSGHSGSFLYQVSTHEQS 3072
H + H + + +S E ++ S E HS S S ++
Sbjct: 1538 EHNHPSFYRERTPRGPSERTRHNPSWRNHRSPSERSQRSSLERRHHSPSQRSHCSPSRKN 1597
Query: 3073 ESS---HGWTGPSTRGRQGSRHEQAQDSSRHSASQYGQDTIRGHPGSSRGGRQGYHHEHS 3129
SS W PS R H + S HS S+ G + S RG Q HH S
Sbjct: 1598 HSSPSERSWRSPSQRN-----HCSPPERSCHSLSERGLHSPSQR--SHRGPSQRRHHSPS 1650
Query: 3130 VDSSGHSGSHHSHTTSQGRSDASRGQSGSRSASRTTRNEEQSGDSSRHSVSRHHEASTHA 3189
+ S S S SH +S R S Q R S + S RH +
Sbjct: 1651 -ERSHRSPSERSHRSSSERRHRSPSQRSHRGPSERSHC---SPSERRHRSPSQRSHRGPS 1706
Query: 3190 DISRHSQAVQGQSEGSRRSRRQGSSVSQDSDSE-GHSEDSERWSGSASRNHRGSVQEQSR 3248
+ HS + + +RRS R S S S SE H SER S S S E+S
Sbjct: 1707 ERRHHSPSKRSHRSPARRSHRSPSERSHHSPSERSHHSPSERRHHSPSERSHCSPSERS- 1765
Query: 3249 HGSRHPRSHHEDRAGHGHSADRSRQSGTRHAETSSGGQAASSHEQARSSPGERHGSRHQQ 3308
H S R H HS E++ SP ER H
Sbjct: 1766 HCSPSERRHRSPSERRHHSPS----------------------EKSHHSPSERS---HHS 1800
Query: 3309 SADSSRHSGIPRGQASSAVRDSRHWGSSGSQASDSEGH---SEESDTQSVSGHGQAGPHQ 3365
++ RHS + R + S R R S S H SE S + S H P +
Sbjct: 1801 PSERRRHSPLERSRHSLLERSHRSPSERRSHRSFERSHRRISERSHSPSEKSH--LSPLE 1858
Query: 3366 QSHQESARDRSGGRSGRSGSFLYQVSTHEQSESAHGRTRTSTGRRQGSHHEQARDSSRHS 3425
+S + R SG++ H SE +H R+ +G RQG E++ SS
Sbjct: 1859 RSRCSPSERRGHSSSGKT--------CHSPSERSH---RSPSGMRQGRTSERSHRSS--- 1904
Query: 3426 ASQEGQDTIRGHPGSSRRGRQGSHYEQSVDRSGHSGSHHSHTTSQGRSDASRGQSGSRSA 3485
+R+ HS S GR+ S + RS
Sbjct: 1905 ----------------------------CERTRHSPSEMRPGRPSGRNHCSPSERSRRSP 1936
Query: 3486 SRQTRNDEQSGDGSRHSWSHHHEASTQADSSRHSQSGQGQSAGPRTSR 3533
++ G+ HS S + T + H GQ P +R
Sbjct: 1937 LKEGLKYSFPGERPSHSLSRDFKNQTTLLGTTHKNPKAGQVWRPEATR 1984
Score = 89.0 bits (219), Expect = 9e-17
Identities = 164/682 (24%), Positives = 239/682 (35%), Gaps = 88/682 (12%)
Query: 2536 EASSRADSSGH---SQVGQGQSEGPRTSRNWGSSF---SQDSDSQGHSEDSERWSGSASR 2589
++ RA + H + VG+ +G R W S Q++ +R SA +
Sbjct: 1355 QSLKRAFQTAHRVIASVGRKPVDGTRPDNLWASKNYYPKQNARDYCLPSSIKRDKRSADK 1414
Query: 2590 -NHHGSAQEQ---LRDGSRHPRSHQEDRAGHGHSADSSR-------QSGTRHTQTSSGGQ 2638
GS +Q L G+ RS Q+ R + R QSG QT+S GQ
Sbjct: 1415 LTPAGSTIKQEDILWGGTVQCRSAQQPRRAYSFQPRPLRLPKPTDSQSGIAF-QTASVGQ 1473
Query: 2639 AASSHEQARSSAGERHGSHHQQSADSSRHSGI--------GHGQASSAVRDSGHRGYSGS 2690
+ ++ SS +++ ++ S+ S++ G S V+ + HR
Sbjct: 1474 PLRTVQKDSSSRSKKNFYRNETSSQESKNLSTPGTRVQARGRILPGSPVKRTWHRHLKDK 1533
Query: 2691 QASDNEGHSE------DSDTQSVSAHGQAGSHQQSHQESARGRSGETSGHSGSFLYQVST 2744
H + H + + +S E ++ S E HS S S
Sbjct: 1534 LTHKEHNHPSFYRERTPRGPSERTRHNPSWRNHRSPSERSQRSSLERRHHSPSQRSHCSP 1593
Query: 2745 HEQSESS---HGWTGPSTRGRQGSRHEQAQDSSRHSASQDGQDTIRGHPGSSRGGRQGYH 2801
++ SS W PS R H + S HS S+ G + S RG Q H
Sbjct: 1594 SRKNHSSPSERSWRSPSQR-----NHCSPPERSCHSLSERGLHS--PSQRSHRGPSQRRH 1646
Query: 2802 HEHSVDSSGHSGSHHSHTTSQGRSDASRGQSGSRSASRTTRNEEQSGDGSRHSGSRHHEA 2861
H S + S S S SH +S R S Q R S S RH
Sbjct: 1647 HSPS-ERSHRSPSERSHRSSSERRHRSPSQRSHRGPS---ERSHCSPSERRHRSPSQRSH 1702
Query: 2862 STHADISRHSQAVQGQSEGSRRSRRQGSSVSQDSDSE-GHSEDSERWSGSASRNHHGSAQ 2920
++ HS + + +RRS R S S S SE H SER S S H S
Sbjct: 1703 RGPSERRHHSPSKRSHRSPARRSHRSPSERSHHSPSERSHHSPSERRHHSPSERSHCSPS 1762
Query: 2921 EQLRDGSRHPRSHQEDRAGHGHSADSSRQSGTRHTQTSSGGQAASSHEQARSSAGERHGS 2980
E+ H + S R RH ++ S + S E++ S ER S
Sbjct: 1763 ER------------------SHCSPSER----RH-RSPSERRHHSPSEKSHHSPSER--S 1797
Query: 2981 HHQQSADSSRHSGIGHGQASSAVRDSGHRGYSGSQASDNEGHSEDSDTQSVSAHGQAGSH 3040
HH S + RHS + + S + + HR S S+ + S +H +
Sbjct: 1798 HHSPS-ERRRHSPLERSRHS--LLERSHR--SPSERRSHRSFERSHRRISERSHSPSEKS 1852
Query: 3041 QQSHQESARGRSGETSGHSGSFLYQVSTHEQSESSHGWTGPSTRGRQGSR-HEQAQDSSR 3099
S E +R E GHS S + H SE SH +GR R H + + +R
Sbjct: 1853 HLSPLERSRCSPSERRGHSSS---GKTCHSPSERSHRSPSGMRQGRTSERSHRSSCERTR 1909
Query: 3100 HSASQYGQDTIRGHPGSSRGGRQGYHHEHSVDSSGHSGSHHSHTTSQGRSDASRGQSGSR 3159
HS S+ PG G E S S G +S + SR
Sbjct: 1910 HSPSEM-------RPGRPSGRNHCSPSERSRRSPLKEGLKYSFPGERPSHSLSRDFKNQT 1962
Query: 3160 SASRTTRNEEQSGDSSRHSVSR 3181
+ TT ++G R +R
Sbjct: 1963 TLLGTTHKNPKAGQVWRPEATR 1984
Score = 87.8 bits (216), Expect = 2e-16
Identities = 138/544 (25%), Positives = 197/544 (36%), Gaps = 72/544 (13%)
Query: 1252 VGQEQSSGSRTSRHQGSSVSQDSDS-----ERHSDDSERLSGSASRN--HHGSSREQSRD 1304
V ++ SS S+ + ++ + SQ+S + R L GS + H + +
Sbjct: 1478 VQKDSSSRSKKNFYRNETSSQESKNLSTPGTRVQARGRILPGSPVKRTWHRHLKDKLTHK 1537
Query: 1305 GSRHPGFHQEDRASHGHSADSSRQSGTHHTESSSHGQAVSSHEQARSSPGERHGSRHQQS 1364
HP F++E R G S T H S + ++ S Q RSS RH S Q+S
Sbjct: 1538 EHNHPSFYRE-RTPRGPS------ERTRHNPSWRNHRSPSERSQ-RSSLERRHHSPSQRS 1589
Query: 1365 ADSSRHSGIGHRQASSAVRDSGHRGSSGSQVTNSEGHSEDSDTQSVSAHGQAGPHQQSHK 1424
H + SS S S + + E S+S G P Q+SH+
Sbjct: 1590 -----HCSPSRKNHSSPSERSWRSPSQRNHCSPPE-----RSCHSLSERGLHSPSQRSHR 1639
Query: 1425 ESARGQSGESSGRSRSFLYQVSSHEQSESTHGQTAPSTGGRQGSRHEQARNSSRHSASQD 1484
++ + S RS + S SE H + + R + + RH +
Sbjct: 1640 GPSQRRHHSPSERSHRSPSERSHRSSSERRHRSPSQRSHRGPSERSHCSPSERRHRSPSQ 1699
Query: 1485 GQDTIRGHPGSSRGGRQGSYHEQSVDRSGHSGYHHSHTTPQGRSDASHGQSGPRSASRQT 1544
R H G S +R HS SH +P RS S + S S +
Sbjct: 1700 -----RSHRGPS-------------ERRHHSPSKRSHRSPARRSHRSPSERSHHSPSER- 1740
Query: 1545 RNEEQSGDGSRHSGS--RHHEPSTRA--GSSRHSQVGQGESAGSKTSRRQGSSVSQDRDS 1600
S HS S RHH PS R+ S S E S R+ S S+
Sbjct: 1741 ---------SHHSPSERRHHSPSERSHCSPSERSHCSPSERRHRSPSERRHHSPSE---- 1787
Query: 1601 EGHSEDSERRSESASRNHYGSAREQSRHGSRNPRSHQ--EDRASHGHSAESSRQSGTRHA 1658
+ H SER S S S E+SRH S RSH+ +R SH S E S + + +
Sbjct: 1788 KSHHSPSERSHHSPSERRRHSPLERSRH-SLLERSHRSPSERRSH-RSFERSHRRISERS 1845
Query: 1659 ETSSGGQAASSQEQARSSPGERHGSRHQQSADSSTDSGTGRRQDSSVVGDSGNRGSSGSQ 1718
+ S S E++R SP ER G S+ T R S G R S S
Sbjct: 1846 HSPSEKSHLSPLERSRCSPSERRG----HSSSGKTCHSPSERSHRSPSGMRQGRTSERSH 1901
Query: 1719 ASDSEGHSEESDTQSVSAHGQAGPHQQSHQESTRGQSGERSGRSGSFLYQVSTHEQSESA 1778
S E + S ++ H + S R S + G SF + +H S
Sbjct: 1902 RSSCE-RTRHSPSEMRPGRPSGRNHCSPSERSRR--SPLKEGLKYSFPGERPSHSLSRDF 1958
Query: 1779 HGRT 1782
+T
Sbjct: 1959 KNQT 1962
Score = 87.0 bits (214), Expect = 3e-16
Identities = 107/454 (23%), Positives = 153/454 (33%), Gaps = 29/454 (6%)
Query: 3413 SHHEQARDSSRHSASQEGQDTIRGHPGSSRRGRQGSHYEQ--SVDRSGHSGSHHSHTTSQ 3470
+H E S + G H S R R S Q S++R HS S SH +
Sbjct: 1535 THKEHNHPSFYRERTPRGPSERTRHNPSWRNHRSPSERSQRSSLERRHHSPSQRSHCSPS 1594
Query: 3471 GRSDASRGQSGSRSASRQTRNDEQSGDGSRHSWSHHHEASTQADSSRHSQSGQGQSAGPR 3530
++ +S + RS S+ RN + S HS S S S R + S R
Sbjct: 1595 RKNHSSPSERSWRSPSQ--RNHCSPPERSCHSLSERGLHSPSQRSHRGPSQRRHHSPSER 1652
Query: 3531 TSRNQGSSVSQDSDSQGHSEDSER-WSGSASRNHRGSAQEQSRDGSRHPTSHHEDRAGHG 3589
+ R+ + S + H S+R G + R+H ++ + R S+ +R H
Sbjct: 1653 SHRSPSERSHRSSSERRHRSPSQRSHRGPSERSHCSPSERRHRSPSQRSHRGPSERRHHS 1712
Query: 3590 HSAESSRQSGTHHAENSSGGQAASSHEQARSSAGERHGSHHQQSADSS------------ 3637
S S R + S S E++ S ER HH S S
Sbjct: 1713 PSKRSHRSPARRSHRSPSERSHHSPSERSHHSPSERR--HHSPSERSHCSPSERSHCSPS 1770
Query: 3638 --RHSGIGHGQASSAVRDSGHRGSSGSQASDSEGHSEDSDTQSVSAHGQAGPHQQSHQES 3695
RH + S S H S S S SE +S H +S E
Sbjct: 1771 ERRHRSPSERRHHSPSEKSHHSPSERSHHSPSERRRHSPLERS--RHSLLERSHRSPSER 1828
Query: 3696 TRGRSAGRSGRSGSFLYQVSTHEQSESAHGRAGPSTGGRQGSRHEQARDSSRHSASQEGQ 3755
RS RS R ++S S S P R + SS + +
Sbjct: 1829 RSHRSFERSHR------RISERSHSPSEKSHLSPLERSRCSPSERRGHSSSGKTCHSPSE 1882
Query: 3756 DTIRGHPGSRRGGRQGSYHEQSVDRSGHSGSHHSHTTSQGRSDASHGQSGSRSASRETRN 3815
+ R G R+G H S +R+ HS S GR+ S + RS +E
Sbjct: 1883 RSHRSPSGMRQGRTSERSHRSSCERTRHSPSEMRPGRPSGRNHCSPSERSRRSPLKEGLK 1942
Query: 3816 EEQSGDGSRHSGSRHHEASTQADSSRHSQSGQGE 3849
G+ HS SR + T + H G+
Sbjct: 1943 YSFPGERPSHSLSRDFKNQTTLLGTTHKNPKAGQ 1976
Score = 82.8 bits (203), Expect = 6e-15
Identities = 143/577 (24%), Positives = 218/577 (37%), Gaps = 82/577 (14%)
Query: 1629 GSRNPRSHQEDRASHGHSAESSR-------QSGTRHAETSSGGQAASSQEQARSSPGERH 1681
G+ RS Q+ R ++ R QSG +T+S GQ + ++ SS +++
Sbjct: 1431 GTVQCRSAQQPRRAYSFQPRPLRLPKPTDSQSGIAF-QTASVGQPLRTVQKDSSSRSKKN 1489
Query: 1682 GSRHQQSADSSTD---SGTGRRQDSSVVGDSGNRGSSGSQASDSEGHSEESDTQSVSAHG 1738
R++ S+ S + GT + ++ S + + D H E +
Sbjct: 1490 FYRNETSSQESKNLSTPGTRVQARGRILPGSPVKRTWHRHLKDKLTHKEHNHPSFYRERT 1549
Query: 1739 QAGPHQQS-HQESTRGQSG--ERSGRSGSFLYQVSTHEQSESAHGRTGPSTGGRQRSRHE 1795
GP +++ H S R ERS RS S ++S + R S+ + R
Sbjct: 1550 PRGPSERTRHNPSWRNHRSPSERSQRSSLERRHHSPSQRSHCSPSRKNHSSPSERSWRSP 1609
Query: 1796 QAR------DSSRHSASQEGQDTIRGHPGSSRGGRQGSHYEQSVDSSGHSGSHHSHTTSQ 1849
R + S HS S+ G + S RG Q H HS S SH +
Sbjct: 1610 SQRNHCSPPERSCHSLSERGLHSPSQR--SHRGPSQRRH---------HSPSERSHRSPS 1658
Query: 1850 ERSDVSRGQSGSRSVSRQTRNEKQSGDGSRHSGSRHHEASSRADSSRHSQVGQGQSSGPR 1909
ERS S + RS S+++ S RH S R S R + S R
Sbjct: 1659 ERSHRSSSERRHRSPSQRSHRGPSERSHCSPSERRHRSPSQR--SHRGPSERRHHSPSKR 1716
Query: 1910 TSRNQGSSVSQDSDSQGHSEDSERWSGSASRNHLGSAWEQSRDGSRHPGSHHEDRAGHGH 1969
+ R+ + + H SER S S S E+S H + H
Sbjct: 1717 SHRSPARRSHRSPSERSHHSPSERSHHSPSERRHHSPSERS----------HCSPSERSH 1766
Query: 1970 SADSSRQSGTRHTESSSRGQAASSHEQARSSAGERHGSHH------QLQSADSSRHSGIG 2023
+ S R RH S R + S E++ S ER SHH + + SRHS +
Sbjct: 1767 CSPSER----RHRSPSERRHHSPS-EKSHHSPSER--SHHSPSERRRHSPLERSRHSLLE 1819
Query: 2024 HGQASSAVRDSGHRGYSGSQASDSEGHSEDSDTQSVSAQGKAGPHQQSHKESARGQSGES 2083
S + R S HR + S SE S+ +S P ++S + + S
Sbjct: 1820 RSHRSPSERRS-HRSFERSHRRISERSHSPSEKSHLS------PLERSRCSPSERRGHSS 1872
Query: 2084 SGRSGSFLYQVSTHEQSESTHGQSAPSTGGRQGSHYDQAQDSS----RHSASQ--EGQDT 2137
SG+ + H SE +H +PS G RQG +++ SS RHS S+ G+ +
Sbjct: 1873 SGK--------TCHSPSERSH--RSPS-GMRQGRTSERSHRSSCERTRHSPSEMRPGRPS 1921
Query: 2138 IRGHPGPSRGGRQGSHQEQSVDRSGHSGSHHSHTTSQ 2174
R H PS R+ +E + G SH+ S+
Sbjct: 1922 GRNHCSPSERSRRSPLKEGL--KYSFPGERPSHSLSR 1956
Score = 82.0 bits (201), Expect = 1e-14
Identities = 135/531 (25%), Positives = 201/531 (37%), Gaps = 71/531 (13%)
Query: 1443 YQVSSHEQSESTHGQTAPSTGGRQGSRHEQARNSSRHSASQDGQDTIRGH--PGSSRGGR 1500
+Q +S Q T + + S + R+E + S++ ++ + RG PGS
Sbjct: 1466 FQTASVGQPLRTVQKDSSSRSKKNFYRNETSSQESKNLSTPGTRVQARGRILPGSPV--- 1522
Query: 1501 QGSYHEQSVDRSGHSGYHHS----HTTPQGRSDAS-HGQSGPRSASRQTRNEEQSGDGSR 1555
+ ++H D+ H ++H TP+G S+ + H S S R++ S +
Sbjct: 1523 KRTWHRHLKDKLTHKEHNHPSFYRERTPRGPSERTRHNPSWRNHRSPSERSQRSSLERRH 1582
Query: 1556 HSGSR----------HHEPSTRA--GSSRHSQVGQGESAGSKTSRRQGSSVSQDRDSEG- 1602
HS S+ H PS R+ S+ + E + S R S SQ R G
Sbjct: 1583 HSPSQRSHCSPSRKNHSSPSERSWRSPSQRNHCSPPERSCHSLSERGLHSPSQ-RSHRGP 1641
Query: 1603 ----HSEDSERRSESASRNHYGSAREQSRHGSRNPRSHQEDRASHGHSAESSRQSGTRHA 1658
H SER S S + S+ E+ RH S + RSH+ G S S H
Sbjct: 1642 SQRRHHSPSERSHRSPSERSHRSSSER-RHRSPSQRSHR------GPSERS-------HC 1687
Query: 1659 ETSSGGQAASSQEQARSSPGERHGSRHQQSADSSTDSGTGRRQDSSVVGDSGNRGSSGSQ 1718
S + SQ R RH S ++S S RR S S + S S
Sbjct: 1688 SPSERRHRSPSQRSHRGPSERRHHSPSKRSHRS-----PARRSHRSPSERSHHSPSERSH 1742
Query: 1719 ASDSEGHSEESDTQSVSAHGQAGPHQQSHQESTRGQSGERSGRSGSFLYQVSTHEQSESA 1778
S SE S S P ++SH + + S R + S H SE +
Sbjct: 1743 HSPSERRH-----HSPSERSHCSPSERSHCSPSERRHRSPSERRHHSPSEKSHHSPSERS 1797
Query: 1779 HGRTGPSTGGRQRSRHEQARDSSRHSASQEGQDTIRGHPGSSRGGRQGSHYEQSVDSSGH 1838
H PS +R RH + SRHS + + P R R + + H
Sbjct: 1798 H--HSPS----ERRRHSPL-ERSRHSLLERSHRS----PSERRSHRSFERSHRRISERSH 1846
Query: 1839 SGSHHSHTTSQERSDVS----RGQSGS-RSVSRQTRNEKQSGDGSRHSGSRHHEASSRAD 1893
S S SH + ERS S RG S S ++ + +S G R + S +
Sbjct: 1847 SPSEKSHLSPLERSRCSPSERRGHSSSGKTCHSPSERSHRSPSGMRQGRTSERSHRSSCE 1906
Query: 1894 SSRH--SQVGQGQSSG-PRTSRNQGSSVSQDSDSQGHSEDSERWSGSASRN 1941
+RH S++ G+ SG S ++ S S + +S ER S S SR+
Sbjct: 1907 RTRHSPSEMRPGRPSGRNHCSPSERSRRSPLKEGLKYSFPGERPSHSLSRD 1957
Score = 80.9 bits (198), Expect = 2e-14
Identities = 110/454 (24%), Positives = 158/454 (34%), Gaps = 28/454 (6%)
Query: 495 SHHEQARDSSRHSASQEGQDTIRGHPGSSRGGRQGSHHEQ--SVNRSGHSGSHHSHTTSQ 552
+H E S + G H S R R S Q S+ R HS S SH +
Sbjct: 1535 THKEHNHPSFYRERTPRGPSERTRHNPSWRNHRSPSERSQRSSLERRHHSPSQRSHCSPS 1594
Query: 553 GRSDASHGQSGSRSASRQT------RNEEQSGDGTRHSGS-RHHEASSQADSSRHSQVGQ 605
++ +S + RS S++ R+ + HS S R H SQ RH +
Sbjct: 1595 RKNHSSPSERSWRSPSQRNHCSPPERSCHSLSERGLHSPSQRSHRGPSQR---RHHSPSE 1651
Query: 606 GQSSGP--RTSRNQGSSVSQDSDSQGHSEDSERWSGSASRNHHGSAQEQSRDGSRHPRSH 663
P R+ R+ + + H SER S S H S ++S G R H
Sbjct: 1652 RSHRSPSERSHRSSSERRHRSPSQRSHRGPSERSHCSPSERRHRSPSQRSHRGPSERRHH 1711
Query: 664 HEDRAGHGHSADSSRKSGTRHTQNSSSGQAASSHEQARS-SAGERHG---SRHQLQSADS 719
+ H A S +S + + +S S ++ S + R S ER S S
Sbjct: 1712 SPSKRSHRSPARRSHRSPSERSHHSPSERSHHSPSERRHHSPSERSHCSPSERSHCSPSE 1771
Query: 720 SRHSGTGHGQASSAVRDSGHRGSSGSQATDSEGHSEDSDTQSVSGHGQAGHHQQSHQESA 779
RH + S S H S S + SE +S + H S + S
Sbjct: 1772 RRHRSPSERRHHSPSEKSHHSPSERSHHSPSERRRHSPLERSRHSLLERSHRSPSERRS- 1830
Query: 780 RDRSGERSRRSGSFLYQVSTHKQSESSHGWTGPSTGVRQGSHHEQARDNSRHSASQDGQD 839
RS ERS R S +H SE SH P R + +S + +
Sbjct: 1831 -HRSFERSHRRIS----ERSHSPSEKSH--LSPLERSRCSPSERRGHSSSGKTCHSPSER 1883
Query: 840 TIRGHPGSSRRGRQGSH-HEQSVDRSGHSGSHHSHTTSQGRSDASRGQSGSRSASRTTRN 898
+ R P R+GR H S +R+ HS S GR+ S + RS +
Sbjct: 1884 SHRS-PSGMRQGRTSERSHRSSCERTRHSPSEMRPGRPSGRNHCSPSERSRRSPLKEGLK 1942
Query: 899 EEQSRDGSRHSGSRHHEASSHADISRHSQAGQGQ 932
+ HS SR + + + H GQ
Sbjct: 1943 YSFPGERPSHSLSRDFKNQTTLLGTTHKNPKAGQ 1976
Score = 80.5 bits (197), Expect = 3e-14
Identities = 96/383 (25%), Positives = 142/383 (37%), Gaps = 41/383 (10%)
Query: 251 LEENKIYERSRSSDGKSSSQVNRSRHENTSQVPLQESRTRKRRGSRVSQDRDSEGHSEDS 310
L E ++ S+ S S + + S E + + P + R+ + R + H S
Sbjct: 1625 LSERGLHSPSQRSHRGPSQRRHHSPSERSHRSPSE--RSHRSSSERRHRSPSQRSHRGPS 1682
Query: 311 ERHSGSASRNHHGSAWEQSRDGSRHPRSHDEDRASHGHSADSSRQSGTRHAETSSRGQTA 370
ER S S H S ++S G R H + SH A S H S R +
Sbjct: 1683 ERSHCSPSERRHRSPSQRSHRGPSERRHHSPSKRSHRSPARRS------HRSPSERSHHS 1736
Query: 371 SSHEQARSSPGERHGSGHQQSADSSRHSATGRGQASSAVSDRGHRGSSGSQASDSEGHSE 430
S E++ SP ER H ++ S S + R S S+R HR S + S
Sbjct: 1737 PS-ERSHHSPSERR---HHSPSERSHCSPSERSHCSP--SERRHRSPSERRHHSPSEKSH 1790
Query: 431 NSDTQSVSGHGKAGLRQQSHQESTRGRSGERSGRSGSSLYQVSTHEQPDSAHGRTGTSTG 490
+S ++ S H + R+ S E +R ERS RS S + +H + +H R +
Sbjct: 1791 HSPSER-SHHSPSERRRHSPLERSRHSLLERSHRSPS---ERRSHRSFERSHRRISERSH 1846
Query: 491 GRQGSHHEQARDSSRHSASQEGQDTIRGHPGSSR--------------GGRQGS----HH 532
H + SR S S+ RGH S + G RQG H
Sbjct: 1847 SPSEKSHLSPLERSRCSPSER-----RGHSSSGKTCHSPSERSHRSPSGMRQGRTSERSH 1901
Query: 533 EQSVNRSGHSGSHHSHTTSQGRSDASHGQSGSRSASRQTRNEEQSGDGTRHSGSRHHEAS 592
S R+ HS S GR+ S + RS ++ G+ HS SR +
Sbjct: 1902 RSSCERTRHSPSEMRPGRPSGRNHCSPSERSRRSPLKEGLKYSFPGERPSHSLSRDFKNQ 1961
Query: 593 SQADSSRHSQVGQGQSSGPRTSR 615
+ + H GQ P +R
Sbjct: 1962 TTLLGTTHKNPKAGQVWRPEATR 1984
Score = 77.8 bits (190), Expect = 2e-13
Identities = 115/427 (26%), Positives = 154/427 (36%), Gaps = 48/427 (11%)
Query: 659 HPRSHHEDRAGHGHSADSSRKSGTRHTQNSSSGQAASSHEQARSSAGERHGSRHQLQSAD 718
HP S + +R G S TRH + + ++ S Q RSS RH S Q
Sbjct: 1541 HP-SFYRERTPRGPS------ERTRHNPSWRNHRSPSERSQ-RSSLERRHHSPSQRSHCS 1592
Query: 719 SSRHSGTGHGQASSAVRDSGHRGSSGSQATDS--EGHSEDSDTQSVSGHGQAGHHQQSHQ 776
SR + + + S + S ++ S E +S G Q HH S
Sbjct: 1593 PSRKNHSSPSERSWRSPSQRNHCSPPERSCHSLSERGLHSPSQRSHRGPSQRRHHSPS-- 1650
Query: 777 ESARDRSGERSRRSGSFLYQVSTHKQSESSHGWTGPSTGVRQGSHHEQARDNSRHSASQD 836
E + ERS RS S +S S GPS R + R S S
Sbjct: 1651 ERSHRSPSERSHRSSS-----ERRHRSPSQRSHRGPSE--RSHCSPSERRHRSPSQRSHR 1703
Query: 837 GQDTIRGHPGSSRRGRQGSH--HEQSVDRSGHSGSHHSHTTSQGRSDASRGQSGSRSASR 894
G R H S R R + H +RS HS S SH + R S + S S
Sbjct: 1704 GPSERRHHSPSKRSHRSPARRSHRSPSERSHHSPSERSHHSPSERRHHSPSERSHCSPSE 1763
Query: 895 TTRNEEQSRDGSRHSGSRHHEASSHADISRHSQAGQGQSEGSRTSRRQGSSVSQDSDS-- 952
+ R S RHH S ++ S HS + +S S + RR+ S + + S
Sbjct: 1764 RSHCSPSERRHRSPSERRHH---SPSEKSHHSPS--ERSHHSPSERRRHSPLERSRHSLL 1818
Query: 953 -EGHSEDSERWSGSASRNHRGSAQEQSRHGSRHPRSHHEDRAGHGHSADSSRQSGTPHAE 1011
H SER R+HR + R RSH H + SR S +
Sbjct: 1819 ERSHRSPSER------RSHRSFERSHRRISE---RSHSPSEKSHLSPLERSRCSPSERRG 1869
Query: 1012 TSSGGQA--ASSHEQARSSPGERHG----SRHQQSADSSRHSGIPRRQASSAVRDSGHWG 1065
SS G+ + S RS G R G H+ S + +RHS R R SG
Sbjct: 1870 HSSSGKTCHSPSERSHRSPSGMRQGRTSERSHRSSCERTRHSPSEMRPG----RPSGRNH 1925
Query: 1066 SSGSQAS 1072
S S+ S
Sbjct: 1926 CSPSERS 1932
Score = 76.6 bits (187), Expect = 5e-13
Identities = 139/594 (23%), Positives = 211/594 (35%), Gaps = 56/594 (9%)
Query: 1684 RHQQSADSSTDSGTGRRQDSSVVGDSGNRGSSGSQASDSEGHS------EESDTQSVSAH 1737
R ++SAD T +G+ +Q+ + G + S+ + +D+QS A
Sbjct: 1407 RDKRSADKLTPAGSTIKQEDILWGGTVQCRSAQQPRRAYSFQPRPLRLPKPTDSQSGIAF 1466
Query: 1738 GQAGPHQ-----QSHQESTRGQSGERSGRSGSFLYQVSTHEQSESAHGRTGPSTGGRQRS 1792
A Q Q S ++ R+ S +ST A GR P + + R+
Sbjct: 1467 QTASVGQPLRTVQKDSSSRSKKNFYRNETSSQESKNLSTPGTRVQARGRILPGSPVK-RT 1525
Query: 1793 RHEQARDSSRHSASQEG----QDTIRG------HPGSSRGGRQGSHYEQ--SVDSSGHSG 1840
H +D H + T RG H S R R S Q S++ HS
Sbjct: 1526 WHRHLKDKLTHKEHNHPSFYRERTPRGPSERTRHNPSWRNHRSPSERSQRSSLERRHHSP 1585
Query: 1841 SHHSHTTSQERSDVSRGQSGSRSVSRQTRNEKQSGDGSRHSGSRHHEASSRADSSRHSQV 1900
S SH + ++ S + RS S+ RN + S HS S S S R
Sbjct: 1586 SQRSHCSPSRKNHSSPSERSWRSPSQ--RNHCSPPERSCHSLSERGLHSPSQRSHRGPSQ 1643
Query: 1901 GQGQSSGPRTSRNQGSSVSQDSDSQGHSEDSER-WSGSASRNHLGSAWEQSRDGSRHPGS 1959
+ S R+ R+ + S + H S+R G + R+H + + R S+
Sbjct: 1644 RRHHSPSERSHRSPSERSHRSSSERRHRSPSQRSHRGPSERSHCSPSERRHRSPSQRSHR 1703
Query: 1960 HHEDRAGHGHSADSSRQSGTRHTESSSRGQAASSHEQARSSAGERHGSHHQLQSADSSRH 2019
+R H S S R R S S S E++ S ER HH
Sbjct: 1704 GPSERRHHSPSKRSHRSPARRSHRSPSERSHHSPSERSHHSPSERR--HHSPSERSHCSP 1761
Query: 2020 SGIGHGQASSAVRDSGHRGYSGSQASDSEGHSEDSDTQSVSAQGKAGPHQQS-------- 2071
S H S S S + S + S S + + P ++S
Sbjct: 1762 SERSHCSPSERRHRSPSERRHHSPSEKSHHSPSERSHHSPSERRRHSPLERSRHSLLERS 1821
Query: 2072 HKESARGQSGESSGRSGSFLYQVSTHEQSESTH----GQSAPSTGGRQGSHYDQAQDSSR 2127
H+ + +S S RS + + S H SE +H +S S R+G + +
Sbjct: 1822 HRSPSERRSHRSFERSHRRISERS-HSPSEKSHLSPLERSRCSPSERRGH---SSSGKTC 1877
Query: 2128 HSASQEGQDTIRGHPGPSRGGRQGSHQEQS----VDRSGHSGSHHSHTTSQGRSDASRGQ 2183
HS S+ R H PS G RQG E+S +R+ HS S GR+ S +
Sbjct: 1878 HSPSE------RSHRSPS-GMRQGRTSERSHRSSCERTRHSPSEMRPGRPSGRNHCSPSE 1930
Query: 2184 SGSRSASRKTYDKEQSGDGSRHSGSHHHEASSWADSSRHSLVGQGQSSGPRTSR 2237
RS ++ G+ HS S + + + H GQ P +R
Sbjct: 1931 RSRRSPLKEGLKYSFPGERPSHSLSRDFKNQTTLLGTTHKNPKAGQVWRPEATR 1984
Score = 75.9 bits (185), Expect = 8e-13
Identities = 110/427 (25%), Positives = 149/427 (34%), Gaps = 49/427 (11%)
Query: 2256 SERRSGSASRNHHGSAQEQSRDGSRHPRSHHEDRAGHGHSAESSRQSGTHHAENS-SGGQ 2314
SER + S +H S E+S+ S R H + H + + S + + S S
Sbjct: 1554 SERTRHNPSWRNHRSPSERSQRSSLERRHHSPSQRSHCSPSRKNHSSPSERSWRSPSQRN 1613
Query: 2315 AASSHEQARSSAGERHGSHHQQSADSSRHSGIGHGQASSAVRDSGHRGSSGSQASDSEGH 2374
S E++ S ER G H S H G + S S S S S SE
Sbjct: 1614 HCSPPERSCHSLSER-GLH---SPSQRSHRGPSQRRHHSPSERSHRSPSERSHRSSSERR 1669
Query: 2375 SEDSDTQSVSAHGQAGPHQQSHQESTRGRSAGRSGRSGSFLYQVSTHEQSESAHGRTGTS 2434
+S S GP ++SH + R S RS + H S+ +H
Sbjct: 1670 H-----RSPSQRSHRGPSERSHCSPSERRHRSPSQRSHRGPSERRHHSPSKRSHRSPARR 1724
Query: 2435 TGGRQGSHHKQARDSSRHSTSQEGQDTIHGHPGSSSGGRQGSHYEQLVDRSGHSGSHHSH 2494
+ H+ + S HS S+ H P +R HS S SH
Sbjct: 1725 S-------HRSPSERSHHSPSERS----HHSPS---------------ERRHHSPSERSH 1758
Query: 2495 TTSQGRSDASHGHSGSRSASRQTRNDEQSGDGSRHSGSR--HHEASSRADSSGHSQVGQG 2552
+ RS S RS S R + S HS S HH S R S +
Sbjct: 1759 CSPSERSHCSPSERRHRSPSE--RRHHSPSEKSHHSPSERSHHSPSERRRHSPLERSRHS 1816
Query: 2553 QSEGPRTSRNWGSSFSQDSDSQGHSEDSERWSGSASRNHHGSAQEQLRDGSRHPRSHQED 2612
E R+ R+ S S + H SER S S S H S E+ R R H
Sbjct: 1817 LLE--RSHRSPSERRSHRSFERSHRRISER-SHSPSEKSHLSPLERSRCSPSERRGHSSS 1873
Query: 2613 -RAGHGHSADSSRQ-SGTRHTQTSSGGQAAS----SHEQARSSAGERHGSHHQQSADSSR 2666
+ H S S R SG R +TS +S H + G G +H ++ SR
Sbjct: 1874 GKTCHSPSERSHRSPSGMRQGRTSERSHRSSCERTRHSPSEMRPGRPSGRNHCSPSERSR 1933
Query: 2667 HSGIGHG 2673
S + G
Sbjct: 1934 RSPLKEG 1940
Score = 75.9 bits (185), Expect = 8e-13
Identities = 104/460 (22%), Positives = 160/460 (34%), Gaps = 48/460 (10%)
Query: 2139 RGHPGPSRGGRQGSHQEQSVDRSGHSGSHHSHTTSQGRSDASRGQSGSRSASRKTYDKEQ 2198
R H PS Q S++R HS S SH + ++ +S + RS S++ +
Sbjct: 1564 RNHRSPSERS-----QRSSLERRHHSPSQRSHCSPSRKNHSSPSERSWRSPSQRNH---- 1614
Query: 2199 SGDGSRHSGSHHHEASSWADSSRHSLVGQGQSSGPRTSRPRGSSVSQDSDSE-GHSEDSE 2257
S + S HSL +G S + S S S SE H SE
Sbjct: 1615 ---------------CSPPERSCHSLSERGLHSPSQRSHRGPSQRRHHSPSERSHRSPSE 1659
Query: 2258 RRSGSASRNHHGSAQEQSRDGSRHPRSHHEDRAGHGHSAESSRQSGTHHAENSSGGQAAS 2317
R S+S H S ++S H + H + S R+ + + G
Sbjct: 1660 RSHRSSSERRHRSPSQRS----------HRGPSERSHCSPSERRHRSPSQRSHRGPSERR 1709
Query: 2318 SHEQARSSAGERHGSHHQQSADSSRHSGIGHGQASSAVRDSGHRGSSGSQASDSE-GHSE 2376
H ++ S H+ ++ S HS S + R H S S S SE H
Sbjct: 1710 HHSPSKRSHRSPARRSHRSPSERSHHSPSERSHHSPSERRH-HSPSERSHCSPSERSHCS 1768
Query: 2377 DSDTQ--SVSAHGQAGPHQQSHQESTRGRSAGRSGRSGSFLYQVSTHEQSESAHGRTGTS 2434
S+ + S S P ++SH + S R + S H E +H R+ +
Sbjct: 1769 PSERRHRSPSERRHHSPSEKSHHSPSERSHHSPSERRRHSPLERSRHSLLERSH-RSPSE 1827
Query: 2435 TGGRQGSHHKQARDSSR-HSTSQEGQDTIHGHPGSSSGGRQGSHYEQLVDRSGHSGSHHS 2493
+ R S R HS S++ + S R+G ++ HS S S
Sbjct: 1828 RRSHRSFERSHRRISERSHSPSEKSHLSPLERSRCSPSERRG---HSSSGKTCHSPSERS 1884
Query: 2494 HTTSQGRSDASHGHSGSRSASRQTRNDEQSGDGSRHSGSRHHEASSRADSSGHSQVGQGQ 2553
H + G RS+ +TR+ R SG H S R+ S + +
Sbjct: 1885 HRSPSGMRQGRTSERSHRSSCERTRHSPSEMRPGRPSGRNHCSPSERSRRSPLKEGLKYS 1944
Query: 2554 SEGPRTSRNWGSSFSQDSDSQGHSEDSER----WSGSASR 2589
G R S + F + G + + + W A+R
Sbjct: 1945 FPGERPSHSLSRDFKNQTTLLGTTHKNPKAGQVWRPEATR 1984
Score = 75.5 bits (184), Expect = 1e-12
Identities = 125/582 (21%), Positives = 193/582 (33%), Gaps = 84/582 (14%)
Query: 2308 ENSSGGQAASSHEQARSSAGERHGSHHQQSADSSRHSGI--------GHGQASSAVRDSG 2359
+ +S GQ + ++ SS +++ ++ S+ S++ G S V+ +
Sbjct: 1467 QTASVGQPLRTVQKDSSSRSKKNFYRNETSSQESKNLSTPGTRVQARGRILPGSPVKRTW 1526
Query: 2360 HRGSSGSQASDSEGHSEDSDTQSVSAHGQAGPHQQSHQESTRGRSAGRSGRSGSFLYQVS 2419
HR D H E + GP E TR + R+ RS S Q S
Sbjct: 1527 HR-----HLKDKLTHKEHNHPSFYRERTPRGP-----SERTRHNPSWRNHRSPSERSQRS 1576
Query: 2420 THEQSESAHGRTGTSTGGRQGSHHKQARDSSRHSTSQEGQDTIHGHPGSSSGGRQGSHYE 2479
+ E+ + + + R+ +H + S S SQ H P S
Sbjct: 1577 SLERRHHSPSQRSHCSPSRK--NHSSPSERSWRSPSQRN----HCSPPERS-------CH 1623
Query: 2480 QLVDRSGHSGSHHSHTTSQGRSDASHGHSGSRSASRQTRNDEQSGDGSRHSGSRHHEASS 2539
L +R HS S SH R S RS S ++ R S R H + S
Sbjct: 1624 SLSERGLHSPSQRSHRGPSQRRHHSPSERSHRSPSERSH---------RSSSERRHRSPS 1674
Query: 2540 RADSSGHSQVGQGQSEGPRTSRNWGSSFSQDSDSQGHSEDSERWSGSASRNHHGSAQEQL 2599
+ G S+ S S+ + S G + R HH ++
Sbjct: 1675 QRSHRGPSE----------------RSHCSPSERRHRSPSQRSHRGPSERRHHSPSKRSH 1718
Query: 2600 RDGSRHPRSHQEDRAGHGHSADSSRQSGTRHTQTSSGGQAASSHEQARSSAGERHGSHHQ 2659
R +R +R+ H S S R + S S E++ S ER H+
Sbjct: 1719 RSPARRSHRSPSERSHHSPSERSHHSPSERRHHSPSERSHCSPSERSHCSPSERR---HR 1775
Query: 2660 QSADSSRHSGIGHGQASSAVRDSGHRGYSGSQASDNEGHS--EDSDTQSVSAHGQAGSHQ 2717
++ HS S + R S S+ HS E S + ++ S +
Sbjct: 1776 SPSERRHHSPSEKSHHSPSER-------SHHSPSERRRHSPLERSRHSLLERSHRSPSER 1828
Query: 2718 QSHQ--ESARGRSGETSGHSGSFLYQVSTHEQSESSHGWTGPSTRGRQGSRHEQAQDSSR 2775
+SH+ E + R E S H SE SH P R R + SS
Sbjct: 1829 RSHRSFERSHRRISERS------------HSPSEKSH--LSPLERSRCSPSERRGHSSSG 1874
Query: 2776 HSASQDGQDTIRGHPGSSRGGRQGYHHEHSVDSSGHSGSHHSHTTSQGRSDASRGQSGSR 2835
+ + + R G +G H S + + HS S GR+ S + R
Sbjct: 1875 KTCHSPSERSHRSPSGMRQGRTSERSHRSSCERTRHSPSEMRPGRPSGRNHCSPSERSRR 1934
Query: 2836 SASRTTRNEEQSGDGSRHSGSRHHEASTHADISRHSQAVQGQ 2877
S + G+ HS SR + T + H GQ
Sbjct: 1935 SPLKEGLKYSFPGERPSHSLSRDFKNQTTLLGTTHKNPKAGQ 1976
Score = 75.1 bits (183), Expect = 1e-12
Identities = 160/669 (23%), Positives = 222/669 (33%), Gaps = 84/669 (12%)
Query: 3349 ESDTQSVSGH---GQAGPHQQSHQESARDRSGGRSGRSGSFLYQVSTHEQSESAHGRTRT 3405
ES ++ ++ H + G Q S R + L+Q S ++AH R
Sbjct: 1312 ESPSRELAAHLRRKRIGATQTSTASLKRQPKKPSQPKFMQLLFQ-SLKRAFQTAH-RVIA 1369
Query: 3406 STGRR--QGSHHEQARDSSRHSASQEGQDTIRGHPGSSRRGRQGSHYEQSVDRSGHSGS- 3462
S GR+ G+ + S + Q +D P S +R ++ S D+ +GS
Sbjct: 1370 SVGRKPVDGTRPDNLWASKNYYPKQNARDYCL--PSSIKRDKR------SADKLTPAGST 1421
Query: 3463 -HHSHTTSQGRSDASRGQSGSRSASRQTR-------NDEQSGDGSRHSWSHHHEASTQAD 3514
G Q R+ S Q R D QSG + + + Q D
Sbjct: 1422 IKQEDILWGGTVQCRSAQQPRRAYSFQPRPLRLPKPTDSQSGIAFQTASVGQPLRTVQKD 1481
Query: 3515 SSRHSQSG----QGQSAGPRTSRNQGSSVSQDSDSQGHSEDSERWSGSASRNHRGSAQEQ 3570
SS S+ + S + G+ V S W HR +
Sbjct: 1482 SSSRSKKNFYRNETSSQESKNLSTPGTRVQARGRILPGSPVKRTW-------HRHLKDKL 1534
Query: 3571 SRDGSRHPTSHHEDRAGHGHSAESSRQSGTHHAENSSGGQAASSHEQARSSAGERHGSHH 3630
+ HP S + +R G S T H + ++ S Q RSS RH S
Sbjct: 1535 THKEHNHP-SFYRERTPRGPSER------TRHNPSWRNHRSPSERSQ-RSSLERRHHSPS 1586
Query: 3631 QQSADSSRHSGIGHGQASSAVRDSGHRGSSGSQASDSEGHSEDSDTQSVSAHGQAGPHQQ 3690
Q+S H SS S S + S E S+S G P Q+
Sbjct: 1587 QRS-----HCSPSRKNHSSPSERSWRSPSQRNHCSPPE-----RSCHSLSERGLHSPSQR 1636
Query: 3691 SHQESTRGRSAGRSGRSGSFLYQVSTHEQSESAH------GRAGPSTGGRQGSRHEQARD 3744
SH+ ++ R S RS + S SE H GPS R + R
Sbjct: 1637 SHRGPSQRRHHSPSERSHRSPSERSHRSSSERRHRSPSQRSHRGPSE--RSHCSPSERRH 1694
Query: 3745 SSRHSASQEGQDTIRGHPGSRRGGRQGSY--HEQSVDRSGHSGSHHSHTTSQGR-----S 3797
S S G R H S+R R + H +RS HS S SH + R S
Sbjct: 1695 RSPSQRSHRGPSERRHHSPSKRSHRSPARRSHRSPSERSHHSPSERSHHSPSERRHHSPS 1754
Query: 3798 DASHGQSGSRSASRETRNEEQSGDGSRHSGSRHHEASTQADSSRHSQSGQGESAGSRRSR 3857
+ SH RS + +S RH + ++ S HS S + + RSR
Sbjct: 1755 ERSHCSPSERSHCSPSERRHRSPSERRHHSPSEKSHHSPSERSHHSPSERRRHSPLERSR 1814
Query: 3858 RQGSSVSQDSDSEAYPEDS--------ERRSESASRNHHGSSREQSR-DGSRHPGSSHRD 3908
S S SE S RS S S H S E+SR S G S
Sbjct: 1815 HSLLERSHRSPSERRSHRSFERSHRRISERSHSPSEKSHLSPLERSRCSPSERRGHSSSG 1874
Query: 3909 TASHVQS-----SPVQSDSSTAKEHGHFSSLSQDSAYHSGIQSRGSPHSSSSYHYQSEGT 3963
H S SP E H SS + HS + R S ++ SE +
Sbjct: 1875 KTCHSPSERSHRSPSGMRQGRTSERSHRSSC--ERTRHSPSEMRPGRPSGRNHCSPSERS 1932
Query: 3964 ERQKGQSGL 3972
R + GL
Sbjct: 1933 RRSPLKEGL 1941
Score = 73.6 bits (179), Expect = 4e-12
Identities = 128/517 (24%), Positives = 181/517 (35%), Gaps = 84/517 (16%)
Query: 1983 ESSSRGQAASSHEQARSSAGERHGSHHQLQSADS-------SRHSGIGHGQASSAVRDSG 2035
+++S GQ + ++ SS +++ ++ S +S +R G S V+ +
Sbjct: 1467 QTASVGQPLRTVQKDSSSRSKKNFYRNETSSQESKNLSTPGTRVQARGRILPGSPVKRTW 1526
Query: 2036 HRGYSGSQASDSEGHSEDSDTQSVSAQGKAGPHQQSHKESARGQSGESSGRSGSFLYQVS 2095
HR D H E + + GP +++ + S RS +
Sbjct: 1527 HR-----HLKDKLTHKEHNHPSFYRERTPRGPSERTRHNPSWRNHRSPSERSQRSSLERR 1581
Query: 2096 THEQSESTH------GQSAPSTGG-RQGSHYDQAQDSSR--HSASQEG--QDTIRGHPGP 2144
H S+ +H S+PS R S + R HS S+ G + R H GP
Sbjct: 1582 HHSPSQRSHCSPSRKNHSSPSERSWRSPSQRNHCSPPERSCHSLSERGLHSPSQRSHRGP 1641
Query: 2145 SRGGRQGSHQEQSVDRSGHSGSHHSHTTSQGRSDASRGQSGSRSASRKTY-----DKEQS 2199
S Q H S +RS S S SH +S R S Q R S +++ + +S
Sbjct: 1642 S----QRRHHSPS-ERSHRSPSERSHRSSSERRHRSPSQRSHRGPSERSHCSPSERRHRS 1696
Query: 2200 GDGSRHSGS---HHHEAS-------------SWADSSRHSLVGQGQSSGPRTSRPRGSSV 2243
H G HH S S ++ S HS + S S
Sbjct: 1697 PSQRSHRGPSERRHHSPSKRSHRSPARRSHRSPSERSHHSPSERSHHSPSERRHHSPSER 1756
Query: 2244 SQDSDSE-GHSEDSERRSGSASRNHHGSAQEQSRDGSRHPRSHHEDRAGHGHS-AESSRQ 2301
S S SE H SERR S S H S E+S S RSHH HS E SR
Sbjct: 1757 SHCSPSERSHCSPSERRHRSPSERRHHSPSEKSHH-SPSERSHHSPSERRRHSPLERSRH 1815
Query: 2302 SGTHHAENSSGGQAASSHEQARSSAGERHGSHHQQSADSSRHSGIGHGQASSAVRDSGHR 2361
S E++ S ER SH R S H + + R
Sbjct: 1816 ---------------SLLERSHRSPSERR-SHRSFERSHRRISERSHSPSEKSHLSPLER 1859
Query: 2362 GSSGSQASDSEGHSEDSDTQSVSAHGQAGPHQQSHQESTRGRSAGRSGRSGSFLYQVSTH 2421
S S+ GHS T H P ++SH+ + R S RS + + H
Sbjct: 1860 --SRCSPSERRGHSSSGKT----CH---SPSERSHRSPSGMRQGRTSERSHRSSCERTRH 1910
Query: 2422 EQSESAHGRTGTSTGGRQGSHHKQARDSSRHSTSQEG 2458
SE GR G +H + SR S +EG
Sbjct: 1911 SPSEMRPGRP-------SGRNHCSPSERSRRSPLKEG 1940
Score = 73.6 bits (179), Expect = 4e-12
Identities = 136/552 (24%), Positives = 183/552 (33%), Gaps = 112/552 (20%)
Query: 259 RSRSSDGKSSSQVNRSRHENTSQVPLQESRTRKRRGSRVSQ----------DRDSEGHSE 308
R+ D S S+ N R+E +SQ ES+ G+RV R H +
Sbjct: 1476 RTVQKDSSSRSKKNFYRNETSSQ----ESKNLSTPGTRVQARGRILPGSPVKRTWHRHLK 1531
Query: 309 DSERHSGSASRNHHGSAWEQSRDGSRHPRSHDEDRASHGHSADSSRQSGT--RHAETSSR 366
D H NH E++ G H+ +H ++ S++S RH S R
Sbjct: 1532 DKLTHK---EHNHPSFYRERTPRGPSERTRHNPSWRNHRSPSERSQRSSLERRHHSPSQR 1588
Query: 367 GQTASSHEQARSSPGERHGSG-----HQQSADSSRHSATGRGQASSAVSDRGHRGSSGSQ 421
+ S + SSP ER H + S HS + RG S S R HRG S
Sbjct: 1589 SHCSPSRKN-HSSPSERSWRSPSQRNHCSPPERSCHSLSERGLHSP--SQRSHRGPSQR- 1644
Query: 422 ASDSEGHSENSDTQSVSGHGKAGLRQQSHQESTRGRSGERSGRSGSSLYQVSTHEQPDSA 481
R S E + ERS RS S H P
Sbjct: 1645 ------------------------RHHSPSERSHRSPSERSHRSSSE----RRHRSPSQR 1676
Query: 482 HGRTGTSTGGRQGSHHEQARDSSRHSASQEGQDTIRGHPGSSRGGRQGSHHEQSVNRSGH 541
R G H + S SQ S RG + HH S RS
Sbjct: 1677 SHR------GPSERSHCSPSERRHRSPSQR----------SHRGPSERRHHSPS-KRSHR 1719
Query: 542 SGSHHSHTTSQGRSDASHGQSGSRSASRQTRNEEQSGDGTRHSGSRHHEASSQADSSRHS 601
S + SH + RS S + S S + RHH S ++ S
Sbjct: 1720 SPARRSHRSPSERSHHSPSERSHHSPSER----------------RHHSPSERSHCSPSE 1763
Query: 602 QVGQGQSSGPRTSRNQGSSVSQDSDSQGHSEDSERWSGSASRNHHGSAQEQSRDGSRHPR 661
+ S R R+ + H SER S S S E+SR S R
Sbjct: 1764 R--SHCSPSERRHRSPSERRHHSPSEKSHHSPSERSHHSPSERRRHSPLERSRH-SLLER 1820
Query: 662 SHHEDRAGHGH-SADSSRKSGTRHTQNSSSGQAASSHEQARSSAGERHGSRHQLQSADSS 720
SH H S + S + + + + S S E++R S ER G
Sbjct: 1821 SHRSPSERRSHRSFERSHRRISERSHSPSEKSHLSPLERSRCSPSERRG----------- 1869
Query: 721 RHSGTGHGQASSAVRDSGHRGSSGSQATDSEGHSEDSDTQSVSGHGQAGHHQQSHQESAR 780
HS +G S + R HR SG + + SE S S + + + S R
Sbjct: 1870 -HSSSGKTCHSPSER--SHRSPSGMRQGRT---SERSHRSSCERTRHSPSEMRPGRPSGR 1923
Query: 781 DR--SGERSRRS 790
+ ERSRRS
Sbjct: 1924 NHCSPSERSRRS 1935
Score = 59.3 bits (142), Expect = 8e-08
Identities = 79/391 (20%), Positives = 139/391 (35%), Gaps = 38/391 (9%)
Query: 87 ESTRKENLPISGHKHRKHSHHDKHEDNKQEENKENRKRPSSL------ERRNNRKGNKG- 139
E +++ +L H + SH N ++ + + PS ER + +G
Sbjct: 1571 ERSQRSSLERRHHSPSQRSHCSPSRKNHSSPSERSWRSPSQRNHCSPPERSCHSLSERGL 1630
Query: 140 ---RSKSPRETGGKRHESSSEKKERKGYSPTHREEEYGKNHHNSSKKEKNKTENTRLGDN 196
+S R +RH S SE+ R +HR ++ S + + +E + +
Sbjct: 1631 HSPSQRSHRGPSQRRHHSPSERSHRSPSERSHRSSSERRHRSPSQRSHRGPSERSHCSPS 1690
Query: 197 RKRLSERLEEKEDNEEGVYDYENTGRMTQKWIQSGHIATYYTIQDEAYDTTDSLLEENKI 256
+R + + + R + + H + + ++ + +
Sbjct: 1691 ERRHRSPSQRSHRGPSERRHHSPSKRSHRSPARRSHRSP----SERSHHSPSERSHHSPS 1746
Query: 257 YERSRSSDGKSSSQVNRSRHENTSQVPLQESRTRKRRGSRVSQDRDSEGHSEDSERHSGS 316
R S +S + H + S+ R + R + H SER S
Sbjct: 1747 ERRHHSPSERSHCSPSERSHCSPSE------RRHRSPSERRHHSPSEKSHHSPSERSHHS 1800
Query: 317 ASRNHHGSAWEQSRDGSRHPRSH--DEDRASHGHSADSSRQSGTRHAETSSRGQTASSHE 374
S S E+SR S RSH +R SH S + S + + + + S S E
Sbjct: 1801 PSERRRHSPLERSRH-SLLERSHRSPSERRSH-RSFERSHRRISERSHSPSEKSHLSPLE 1858
Query: 375 QARSSPGERHGSGHQQSADSSRHSATGRGQASSAVSDRGHRGSSGSQASDSEGHSENSDT 434
++R SP ER G HS++G+ + S+R HR SG + + S S
Sbjct: 1859 RSRCSPSERRG-----------HSSSGK--TCHSPSERSHRSPSGMRQGRTSERSHRSSC 1905
Query: 435 QSVSGHGKAGLRQQSHQESTRGRSGERSGRS 465
+ + H + +R ERS RS
Sbjct: 1906 ER-TRHSPSEMRPGRPSGRNHCSPSERSRRS 1935
>gi|4504487 histidine rich calcium binding protein precursor [Homo
sapiens]
Length = 699
Score = 94.7 bits (234), Expect = 2e-18
Identities = 137/633 (21%), Positives = 202/633 (31%), Gaps = 77/633 (12%)
Query: 1073 DSEGHSEESDTQSVSGHGQDGPHQ-QSHQESARDWSGGRSGRSGSFIYQVSTHEQSESAH 1131
D G +++ V+G ++ + + H S RD S + +H E
Sbjct: 33 DGLGFRNRNNSTGVAGLSEEASAELRHHLHSPRDHPDENKDVSTENGHHFWSHPDREKED 92
Query: 1132 GRTRTSTGRRQGSHHEQARDSSRHSASQEGQDTIRAHPGSRRGGR-QGSHH-EQSVDRSG 1189
G H Q S G++ H G RG R GS E S +
Sbjct: 93 EDVSKEYGHLLPGHRSQDHKVGDEGVS--GEEVFAEHGGQARGHRGHGSEDTEDSAEHRH 150
Query: 1190 HSGSHHSHTTSQGRSD----ASHGQSGSRSASRQTRKDKQSGDGSRHSGSRHHEAASWAD 1245
H SH SH+ D + H R R + G+ EA++
Sbjct: 151 HLPSHRSHSHQDEDEDEVVSSEHHHHILRHGHRGHDGEDDEGEEEEEEEEEEEEASTEYG 210
Query: 1246 SSRH------SQVGQEQSSGSR----TSRHQGSSVSQDSDSERHSDDSERLSGSASRN-- 1293
H S+ ++ S G + RHQG D D + DD + R+
Sbjct: 211 HQAHRHRGHGSEEDEDVSDGHHHHGPSHRHQGHEEDDDDDDDDDDDDDDDDVSIEYRHQA 270
Query: 1294 --HHGSSREQSRDGSRHPGFHQEDRASHGHSADSSRQSGTHHTESSSHGQAVSSHEQARS 1351
H G E+ D S G H D SH H + + S+ +G H+ R
Sbjct: 271 HRHQGHGIEEDEDVS--DGHHHRD-PSHRHRSHEEDDNDDDDV-STEYGHQAHRHQDHRK 326
Query: 1352 SPGERHGSRHQQSADSSRHSGIGHRQASSAVRDSGHRGSSGSQVTNSEGHSEDSDTQSVS 1411
E H RH G HR S R G Q + E+ + + ++
Sbjct: 327 EEVEAVSGEHHHHVPDHRHQG--HRDEEEDEDVSTERWHQGPQHVHHGLVDEEEEEEEIT 384
Query: 1412 AHGQAGPHQQSHKESARGQSGESSGRSRSFLYQVSSHEQSESTHGQTAPSTGGRQGSRHE 1471
Q G + SH+ RG + + +V H H P + S E
Sbjct: 385 V--QFGHYVASHQP--RGHKSDEEDFQDEYKTEVPHH------HHHRVPREEDEEVSA-E 433
Query: 1472 QARNSSRHSASQDGQDTIRGHPGSSRGGRQGSYHEQSVDRSGHSGYH-HSHTTPQGRSDA 1530
+ H S ++T GH G++GS E S GH+ SH +
Sbjct: 434 LGHQAPSHRQSHQDEET--GH------GQRGSIKEMSHHPPGHTVVKDRSHLRKDDSEEE 485
Query: 1531 SHGQSGPRSASRQTRNEEQSGDGSRHSGSRHHEPSTRAGSSRHSQVGQGESAGSKTSRRQ 1590
+ P S + EQ G+ H GSR E + E G S Q
Sbjct: 486 KEKEEDPGSHEEDDESSEQGEKGTHH-GSRDQEDE------------EDEEEGHGLSLNQ 532
Query: 1591 GSSVSQDRDSEGHSEDSERRSESAS-----RNHYGSAREQSRHGSR----------NPRS 1635
+D++ E ED ERR E A + E+ G NP
Sbjct: 533 EEEEEEDKEEEEEEEDEERREERAEVGAPLSPDHSEEEEEEEEGLEEDEPRFTIIPNPLD 592
Query: 1636 HQEDRASHGHSAESSRQSGTRHAETSSGGQAAS 1668
+E+ ES +G + A+ Q S
Sbjct: 593 RREEAGGASSEEESGEDTGPQDAQEYGNYQPGS 625
Score = 91.7 bits (226), Expect = 1e-17
Identities = 122/599 (20%), Positives = 201/599 (33%), Gaps = 73/599 (12%)
Query: 1158 SQEGQDTIRAHPGSRRGGRQGSHHEQSVDRSGHSGSHHSHTTSQGRSDAS------HGQS 1211
S+E +R H S R H +++ D S +G H + + D H
Sbjct: 50 SEEASAELRHHLHSPR-----DHPDENKDVSTENGHHFWSHPDREKEDEDVSKEYGHLLP 104
Query: 1212 GSRSASRQTRKDKQSGD------GSRHSGSRHHEAASWADSSRHSQVGQEQSSGSRTSRH 1265
G RS + + SG+ G + G R H + DS+ H + R+ H
Sbjct: 105 GHRSQDHKVGDEGVSGEEVFAEHGGQARGHRGHGSEDTEDSAEH----RHHLPSHRSHSH 160
Query: 1266 QGSSVSQDSDSERHSDDSERLSGSASRNHHGSS---------REQSRDGSRHPGFHQEDR 1316
Q +D D S+ + R H G E+ + S G
Sbjct: 161 Q----DEDEDEVVSSEHHHHILRHGHRGHDGEDDEGEEEEEEEEEEEEASTEYGHQAHRH 216
Query: 1317 ASHGHSADSSRQSGTHHTESSSHGQAVSSHEQARSSPGERHGS-------RHQQSADSSR 1369
HG D G HH S Q + + RHQ + R
Sbjct: 217 RGHGSEEDEDVSDGHHHHGPSHRHQGHEEDDDDDDDDDDDDDDDDVSIEYRHQ----AHR 272
Query: 1370 HSGIGHRQASSAVRDSGHRGSSGSQVTNSEGHSEDSDTQSVSAHGQAGPHQQSHKESARG 1429
H G G + HR S ++ E ++D D + H QA HQ KE
Sbjct: 273 HQGHGIEEDEDVSDGHHHRDPSHRHRSHEEDDNDDDDVSTEYGH-QAHRHQDHRKEEVEA 331
Query: 1430 QSGESSGRSRSFLYQVSSHEQSESTHGQTAPSTGGRQGSRHEQARNSSRHSASQDGQDTI 1489
SGE +Q E+ + + + QG +H + ++ + T+
Sbjct: 332 VSGEHHHHVPDHRHQGHRDEEED----EDVSTERWHQGPQH--VHHGLVDEEEEEEEITV 385
Query: 1490 R-GHPGSSRGGRQGSYHEQSV--DRSGHSGYHHSHTTPQGRSDASHGQSGPRSAS-RQTR 1545
+ GH +S R E+ + +HH H P+ + + G ++ S RQ+
Sbjct: 386 QFGHYVASHQPRGHKSDEEDFQDEYKTEVPHHHHHRVPREEDEEVSAELGHQAPSHRQSH 445
Query: 1546 NEEQSGDGSRHSGSR--HHEPSTRAGSSRHSQVGQGESAGSKTSRRQGSSVSQDRDSEGH 1603
+E++G G R S HH P R S + + +S K S +D +S
Sbjct: 446 QDEETGHGQRGSIKEMSHHPPGHTVVKDR-SHLRKDDSEEEKEKEEDPGSHEEDDES--- 501
Query: 1604 SEDSERRSESASRNHYGSAREQSRHGSRNPRSHQEDRASHGHSAESSRQSGTRHAETSSG 1663
SE E+ + SR+ E+ HG + +E+ E + AE +
Sbjct: 502 SEQGEKGTHHGSRDQEDEEDEEEGHGLSLNQEEEEEEDKEEEEEEEDEERREERAEVGAP 561
Query: 1664 GQAASSQEQARSSPGERHGS-----------RHQQSADSSTDSGTGRRQDSSVVGDSGN 1711
S+E+ G R +++ +S++ +G + GN
Sbjct: 562 LSPDHSEEEEEEEEGLEEDEPRFTIIPNPLDRREEAGGASSEEESGEDTGPQDAQEYGN 620
Score = 91.3 bits (225), Expect = 2e-17
Identities = 127/588 (21%), Positives = 180/588 (30%), Gaps = 75/588 (12%)
Query: 3342 DSEGHSEESDTQSVSGHGQ-AGPHQQSHQESARDRSGGRSGRSGSFLYQVSTHEQSESAH 3400
D G +++ V+G + A + H S RD S + +H E
Sbjct: 33 DGLGFRNRNNSTGVAGLSEEASAELRHHLHSPRDHPDENKDVSTENGHHFWSHPDREKED 92
Query: 3401 GRTRTSTGRRQGSHHEQARDSSRHSASQEGQDTIRGHPGSSR--RGRQGSHYEQSVDRSG 3458
G H Q S G++ H G +R RG E S +
Sbjct: 93 EDVSKEYGHLLPGHRSQDHKVGDEGVS--GEEVFAEHGGQARGHRGHGSEDTEDSAEHRH 150
Query: 3459 HSGSHHSHTTSQGRSD----ASRGQSGSRSASRQTRNDEQSGDGSRHSWSHHHEASTQAD 3514
H SH SH+ D + R R ++ G+ EAST+
Sbjct: 151 HLPSHRSHSHQDEDEDEVVSSEHHHHILRHGHRGHDGEDDEGEEEEEEEEEEEEASTEYG 210
Query: 3515 SSRHSQSGQGQSAGPRTS----------RNQGSSVSQDSDSQGHSEDSE-----RWSGSA 3559
H G G S R+QG D D +D + + A
Sbjct: 211 HQAHRHRGHGSEEDEDVSDGHHHHGPSHRHQGHEEDDDDDDDDDDDDDDDDVSIEYRHQA 270
Query: 3560 SRNHRGSAQEQSRDGSRHPTSHHEDRAGHGHSAESSRQSGTHHAENSSGGQAASSHEQAR 3619
R H+G E+ D S HH H H + + G QA + +
Sbjct: 271 HR-HQGHGIEEDEDVS---DGHHHRDPSHRHRSHEEDDNDDDDVSTEYGHQAHRHQDHRK 326
Query: 3620 SSAGERHGSHHQQSADSSRHSGIGHGQASSAVRDSGHRGSSGSQASDSEGHSEDSDTQSV 3679
G HH D H GH S R G Q E+ + + +
Sbjct: 327 EEVEAVSGEHHHHVPD---HRHQGHRDEEEDEDVSTERWHQGPQHVHHGLVDEEEEEEEI 383
Query: 3680 SAHGQAGPHQQSHQESTRGRSAGRSGRSGSFLYQVSTHEQSESAHGRAGPSTGGRQGSRH 3739
+ Q G + SHQ RG + + +V H H P + S
Sbjct: 384 TV--QFGHYVASHQP--RGHKSDEEDFQDEYKTEVPHH------HHHRVPREEDEEVSA- 432
Query: 3740 EQARDSSRHSASQEGQDTIRGHPGSRRGGRQGSYHEQSVDRSGHSGSHH--SHTTSQGRS 3797
E + H S + ++T GH G++GS E S HH HT + RS
Sbjct: 433 ELGHQAPSHRQSHQDEET--GH------GQRGSIKEMS---------HHPPGHTVVKDRS 475
Query: 3798 DASHGQSGSRSASRETRNEEQSGDGSRHSGSR--HHEASTQADSSRHSQSGQGESAGSRR 3855
S E + D S G + HH SR + + E G
Sbjct: 476 HLRKDDSEEEKEKEEDPGSHEEDDESSEQGEKGTHH-------GSRDQEDEEDEEEGHGL 528
Query: 3856 SRRQGSSVSQDSDSEAYPEDSERRSESAS-----RNHHGSSREQSRDG 3898
S Q +D + E ED ERR E A H E+ +G
Sbjct: 529 SLNQEEEEEEDKEEEEEEEDEERREERAEVGAPLSPDHSEEEEEEEEG 576
Score = 90.9 bits (224), Expect = 2e-17
Identities = 138/624 (22%), Positives = 205/624 (32%), Gaps = 95/624 (15%)
Query: 434 TQSVSGHGKAGLRQQSHQESTRGRSGERSGRSGSSLYQVSTHEQPDSAHGRTGTSTGGRQ 493
TQ + G G G R +++ G S E S L+ S + PD + T G
Sbjct: 27 TQQLRGDG-LGFRNRNNSTGVAGLSEEASAELRHHLH--SPRDHPDE-NKDVSTENGHHF 82
Query: 494 GSHHEQARD----------------SSRHSASQEG---QDTIRGHPGSSRGGR-QGSHH- 532
SH ++ ++ S H EG ++ H G +RG R GS
Sbjct: 83 WSHPDREKEDEDVSKEYGHLLPGHRSQDHKVGDEGVSGEEVFAEHGGQARGHRGHGSEDT 142
Query: 533 EQSVNRSGHSGSHHSHTTSQGRSD----ASHGQSGSRSASRQTRNEEQSGDGTRHSGSRH 588
E S H SH SH+ D + H R R E+ G+
Sbjct: 143 EDSAEHRHHLPSHRSHSHQDEDEDEVVSSEHHHHILRHGHRGHDGEDDEGEEEEEEEEEE 202
Query: 589 HEASSQADSSRHSQVGQGQSS-----------GPRTSRNQGSSVSQDSDSQGHSEDSE-- 635
EAS++ H G G GP + R+QG D D +D +
Sbjct: 203 EEASTEYGHQAHRHRGHGSEEDEDVSDGHHHHGP-SHRHQGHEEDDDDDDDDDDDDDDDD 261
Query: 636 ---RWSGSASRNH-HGSAQEQS-------RDGSRHPRSHHEDRAGHGHSADSSRKSGTRH 684
+ A R+ HG +++ RD S RSH ED + RH
Sbjct: 262 VSIEYRHQAHRHQGHGIEEDEDVSDGHHHRDPSHRHRSHEEDDNDDDDVSTEYGHQAHRH 321
Query: 685 TQNSSSGQAASSHEQARSSAGERH-GSRHQLQSADSSR---HSG---TGHGQASSAVRDS 737
+ A S E RH G R + + D S H G HG +
Sbjct: 322 QDHRKEEVEAVSGEHHHHVPDHRHQGHRDEEEDEDVSTERWHQGPQHVHHGLVDEEEEEE 381
Query: 738 GHRGSSGSQATDSE--GHSEDSDTQSVSGHGQAGHHQQSHQESARDRSGERSRRSGSFLY 795
G + GH D + + HH H R+ E S G +
Sbjct: 382 EITVQFGHYVASHQPRGHKSDEEDFQDEYKTEVPHHH--HHRVPREEDEEVSAELG---H 436
Query: 796 QVSTHKQS----ESSHGWTGPSTGVRQGSHHEQ----ARDNSRHSASQDGQDTIRGHPGS 847
Q +H+QS E+ HG G +++ SHH +D S H D ++
Sbjct: 437 QAPSHRQSHQDEETGHGQRG---SIKEMSHHPPGHTVVKDRS-HLRKDDSEEE------K 486
Query: 848 SRRGRQGSHHE-QSVDRSGHSGSHHSHTTSQGRSDASRGQSGSRSASRTTRNEEQSRDGS 906
+ GSH E G G+HH + D G S + +++ +
Sbjct: 487 EKEEDPGSHEEDDESSEQGEKGTHHGSRDQEDEEDEEEGHGLSLNQEEEEEEDKEEEEEE 546
Query: 907 RHSGSRHHEASSHADIS-RHSQAGQGQSEGSRTSRRQGSSVSQ--DSDSEGHSEDSERWS 963
R A A +S HS+ + + EG + + + D E SE S
Sbjct: 547 EDEERREERAEVGAPLSPDHSEEEEEEEEGLEEDEPRFTIIPNPLDRREEAGGASSEEES 606
Query: 964 GSASRNHRGSAQEQSRHGSRHPRS 987
G + Q+ +G+ P S
Sbjct: 607 GEDT-----GPQDAQEYGNYQPGS 625
Score = 90.9 bits (224), Expect = 2e-17
Identities = 128/653 (19%), Positives = 200/653 (30%), Gaps = 101/653 (15%)
Query: 2718 QSHQESARGRSGETSGHSGSFLYQVSTHEQSESSHGWTGPSTRGRQGSRHEQAQDSSRHS 2777
+ H + + S E H S + E +G P R +QD
Sbjct: 65 RDHPDENKDVSTENGHHFWSHPDREKEDEDVSKEYGHLLPGHR---------SQDHKVGD 115
Query: 2778 ASQDGQDTIRGHPGSSRGGRQGYHHEHSVDSSGHSGSHHSHTTSQGRSDASRGQSGSRSA 2837
G++ H G +RG H H + + S H H S RS
Sbjct: 116 EGVSGEEVFAEHGGQARG-----HRGHGSEDTEDSAEHRHHLPSH------------RSH 158
Query: 2838 SRTTRNEEQSGDGSRHSGSRHHEASTHADISRHSQAVQGQSEGSRRSRRQGSSVSQDSDS 2897
S +E++ H HH I RH G R + ++ +
Sbjct: 159 SHQDEDEDEVVSSEHH----HH-------ILRH---------GHRGHDGEDDEGEEEEEE 198
Query: 2898 EGHSEDSERWSGSASRNHHGSAQEQLRDGSRHPRSHQEDRAGHGHSADSSRQSGTRHTQT 2957
E E++ G + H G E+ D S GH H S R G
Sbjct: 199 EEEEEEASTEYGHQAHRHRGHGSEEDEDVSD----------GHHHHGPSHRHQGHEEDDD 248
Query: 2958 SSGGQAASSHEQARSSAGERHGSHHQQSADSSRHSGIGHGQASSAVRDSGHRGYSGSQAS 3017
+ S RH +H RH G G + HR S S
Sbjct: 249 DDDDDDDDDDDDD-VSIEYRHQAH--------RHQGHGIEEDEDVSDGHHHRDPSHRHRS 299
Query: 3018 DNEGHSEDSDTQSVSAHGQAGSHQQSHQESARGRSGETSGHSGSFLYQVSTHEQSESSHG 3077
E ++D D + H QA HQ +E SGE H +Q E+ +
Sbjct: 300 HEEDDNDDDDVSTEYGH-QAHRHQDHRKEEVEAVSGEHHHHVPDHRHQGHRDEEEDEDVS 358
Query: 3078 WTGPSTRGRQGSRH-----EQAQDSSRHSASQYGQDTIRGHPGSSRGGRQGYHHEHSVDS 3132
+ R QG +H ++ Q+G P + + + E+ +
Sbjct: 359 ----TERWHQGPQHVHHGLVDEEEEEEEITVQFGHYVASHQPRGHKSDEEDFQDEYKTEV 414
Query: 3133 SGHSGSHHSHTTSQGRSDASRGQSGSRSASRTTRNEEQSGDSSRHSVSR-HHEASTHADI 3191
H HH + + S + R + +E++G R S+ H H +
Sbjct: 415 PHH---HHHRVPREEDEEVSAELGHQAPSHRQSHQDEETGHGQRGSIKEMSHHPPGHTVV 471
Query: 3192 SRHSQAVQGQSEGSRRSRRQGSSVSQDSDSEGHSEDSERWSGSASRNHRGSVQEQSRHGS 3251
S + SE + ++ D H ED E S+ + +G + HGS
Sbjct: 472 KDRSHLRKDDSEEEK---------EKEEDPGSHEEDDE----SSEQGEKG-----THHGS 513
Query: 3252 RHPRSHHEDRAGHGHSADRSRQSGTRHAETSSGGQAASSHEQAR-SSPGERHGSRHQQSA 3310
R ++ GHG S ++ + E E+A +P S ++
Sbjct: 514 RDQEDEEDEEEGHGLSLNQEEEEEEDKEEEEEEEDEERREERAEVGAPLSPDHSEEEEEE 573
Query: 3311 DSSRHSGIPRGQASSAVRDSRHWGSSGSQASDSEGHSEESDTQSVSGHGQAGP 3363
+ PR D R AS E E++ Q +G P
Sbjct: 574 EEGLEEDEPRFTIIPNPLDRR---EEAGGASSEEESGEDTGPQDAQEYGNYQP 623
Score = 90.5 bits (223), Expect = 3e-17
Identities = 128/653 (19%), Positives = 197/653 (30%), Gaps = 81/653 (12%)
Query: 2401 RGRSAGRSGRSGSFLYQVSTHEQSESAHGRTGTSTGGRQGSHH--KQARDSSRHSTSQEG 2458
R S G +G S ++ H S H G H R+ S+E
Sbjct: 40 RNNSTGVAGLSEEASAELRHHLHSPRDHPDENKDVSTENGHHFWSHPDREKEDEDVSKEY 99
Query: 2459 QDTIHGHPGSSS--GGRQGSHYEQLVDRSGHSGSHHSHTTSQGRSDASHGHS--GSRSAS 2514
+ GH G S E + G + H H + A H H RS S
Sbjct: 100 GHLLPGHRSQDHKVGDEGVSGEEVFAEHGGQARGHRGHGSEDTEDSAEHRHHLPSHRSHS 159
Query: 2515 RQTRNDEQSGDGSRHSGSRHHEASSRADSSGHSQVGQGQSEGPRTSRNWGSSFSQDSDSQ 2574
Q ++++ S HH R GH G+ EG ++ + +
Sbjct: 160 HQDEDEDEV------VSSEHHHHILRHGHRGHD--GE-DDEG-----------EEEEEEE 199
Query: 2575 GHSEDSERWSGSASRNHHGSAQEQLRDGSRHPRSHQEDRAGHGHSADSSRQSGTRHTQTS 2634
E++ G + H G E+ D S GH H S R G
Sbjct: 200 EEEEEASTEYGHQAHRHRGHGSEEDEDVSD----------GHHHHGPSHRHQGHEEDDDD 249
Query: 2635 SGGQAASSHEQARSSAGERHGSHHQQSADSSRHSGIGHGQASSAVRDSGHRGYSGSQASD 2694
+ S RH +H RH G G + HR S S
Sbjct: 250 DDDDDDDDDDDD-VSIEYRHQAH--------RHQGHGIEEDEDVSDGHHHRDPSHRHRSH 300
Query: 2695 NEGHSEDSDTQSVSAHGQAGSHQQSHQESARGRSGETSGHSGSFLYQVSTHEQSESSHGW 2754
E ++D D + H QA HQ +E SGE H +Q E+ +
Sbjct: 301 EEDDNDDDDVSTEYGH-QAHRHQDHRKEEVEAVSGEHHHHVPDHRHQGHRDEEEDEDVS- 358
Query: 2755 TGPSTRGRQGSRH-----EQAQDSSRHSASQDGQDTIRGHPGSSRGGRQGYHHEHSVDSS 2809
+ R QG +H ++ Q G P + + + E+ +
Sbjct: 359 ---TERWHQGPQHVHHGLVDEEEEEEEITVQFGHYVASHQPRGHKSDEEDFQDEYKTEVP 415
Query: 2810 GHSGSHHSHTTSQGRSDASRGQSGSRSASRTTRNEEQSGDGSRHS-GSRHHEASTHADIS 2868
H HH + + S + R + +E++G G R S H H +
Sbjct: 416 HH---HHHRVPREEDEEVSAELGHQAPSHRQSHQDEETGHGQRGSIKEMSHHPPGHTVVK 472
Query: 2869 RHSQAVQGQSEGSRRSRRQGSSVSQDSDSEGHSEDSERWSGSASRNHHGSAQEQLRDGSR 2928
S + SE + ++ D H ED E HH GSR
Sbjct: 473 DRSHLRKDDSEEEK---------EKEEDPGSHEEDDESSEQGEKGTHH---------GSR 514
Query: 2929 HPRSHQEDRAGHGHSADSSRQSGTRHTQTSSGGQAASSHEQARSSAGERHGSHHQQSADS 2988
+++ GHG S + + + + + R+ G H + +
Sbjct: 515 DQEDEEDEEEGHGLSLNQEEEE--EEDKEEEEEEEDEERREERAEVGAPLSPDHSEEEEE 572
Query: 2989 SRHSGIGHGQASSAVRDSGHRGYSGSQASDNEGHSEDSDTQSVSAHG--QAGS 3039
+ + + R AS E ED+ Q +G Q GS
Sbjct: 573 EEEGLEEDEPRFTIIPNPLDRREEAGGASSEEESGEDTGPQDAQEYGNYQPGS 625
Score = 79.7 bits (195), Expect = 5e-14
Identities = 121/559 (21%), Positives = 178/559 (31%), Gaps = 82/559 (14%)
Query: 1800 SSRHSASQEG---QDTIRGHPGSSRG--GRQGSHYEQSVDSSGHSGSHHSHTTSQERSDV 1854
S H EG ++ H G +RG G E S + H SH SH+ E D
Sbjct: 108 SQDHKVGDEGVSGEEVFAEHGGQARGHRGHGSEDTEDSAEHRHHLPSHRSHSHQDEDEDE 167
Query: 1855 SRGQSGSRSVSRQTR----NEKQSGDGSRHSGSRHHEASSRADSSRHSQVGQGQSS---- 1906
+ R E G+ EAS+ H G G
Sbjct: 168 VVSSEHHHHILRHGHRGHDGEDDEGEEEEEEEEEEEEASTEYGHQAHRHRGHGSEEDEDV 227
Query: 1907 -------GPRTSRNQGSSVSQDSDSQGHSEDSE-----RWSGSASRNHLGSAWEQSRDGS 1954
GP + R+QG D D +D + + A R H G E+ D S
Sbjct: 228 SDGHHHHGP-SHRHQGHEEDDDDDDDDDDDDDDDDVSIEYRHQAHR-HQGHGIEEDEDVS 285
Query: 1955 RHPGSHHEDRAGHGHSADSSRQSGTRHTESSSRGQAASSHEQARSSAGERHGSHHQLQSA 2014
G HH D H H + + S+ G A H+ R E H
Sbjct: 286 --DGHHHRD-PSHRHRSHEEDDNDDDDV-STEYGHQAHRHQDHRKEEVEAVSGEHHHHVP 341
Query: 2015 DSSRHSGIGHGQASSAVRDSGHRGYSGSQASDSEGHSEDSDTQSVSAQGKAGPHQQSHKE 2074
D H GH S R + G Q E+ + + ++ Q G + SH+
Sbjct: 342 D---HRHQGHRDEEEDEDVSTERWHQGPQHVHHGLVDEEEEEEEITVQ--FGHYVASHQ- 395
Query: 2075 SARGQSGESSGRSGSFLYQVSTHEQSESTHGQSAPSTGGRQGSHYDQAQDSSRHSASQEG 2134
RG + + +V H H P + S + + H S +
Sbjct: 396 -PRGHKSDEEDFQDEYKTEVPHH------HHHRVPREEDEEVS-AELGHQAPSHRQSHQD 447
Query: 2135 QDTIRGHPGPSRGGRQGSHQEQSVDRSGHS-GSHHSHTTSQGRSDASRGQSGSRSASRKT 2193
++T GH G++GS +E S GH+ SH + D+ +
Sbjct: 448 EET--GH------GQRGSIKEMSHHPPGHTVVKDRSHLR---KDDSEEEKEKEEDPGSHE 496
Query: 2194 YDKEQSGDGSRHSGSHHHEASSWADSSRHSLVGQGQSSGPRTSRPRGSSVSQDSDSEGHS 2253
D E S G + G+HH SR + + G S + +D + E
Sbjct: 497 EDDESSEQGEK--GTHH--------GSRDQEDEEDEEEGHGLSLNQEEEEEEDKEEEEEE 546
Query: 2254 EDSERRS-----GSASRNHHGSAQEQSRDGSR----------HPRSHHEDRAGHGHSAES 2298
ED ERR G+ H +E+ +G +P E+ G ES
Sbjct: 547 EDEERREERAEVGAPLSPDHSEEEEEEEEGLEEDEPRFTIIPNPLDRREEAGGASSEEES 606
Query: 2299 SRQSGTHHAENSSGGQAAS 2317
+G A+ Q S
Sbjct: 607 GEDTGPQDAQEYGNYQPGS 625
Score = 79.3 bits (194), Expect = 7e-14
Identities = 115/565 (20%), Positives = 174/565 (30%), Gaps = 92/565 (16%)
Query: 2195 DKEQSGDGSRHSGSHHHEASSWADSSR---HSLVGQGQSSGPRTSRPRGSSVSQDSDSEG 2251
+K+ S + H SH D S+ H L G R + V + S
Sbjct: 71 NKDVSTENGHHFWSHPDREKEDEDVSKEYGHLLPGH---------RSQDHKVGDEGVS-- 119
Query: 2252 HSEDSERRSGSASRNHHGSAQEQSRDGSRHPRSHHEDRAGHGHSAESSRQ--SGTHHAEN 2309
E+ G +R H G E + D + H R H H H E + S HH
Sbjct: 120 -GEEVFAEHGGQARGHRGHGSEDTEDSAEH-RHHLPSHRSHSHQDEDEDEVVSSEHHHHI 177
Query: 2310 SSGGQAASSHEQARSSAGERHGSHHQQSADSSRHSGI---GHGQASSAVRDSGHRGSSGS 2366
G E E ++++ H GHG GH S
Sbjct: 178 LRHGHRGHDGEDDEGEEEEEEEEEEEEASTEYGHQAHRHRGHGSEEDEDVSDGHHHHGPS 237
Query: 2367 QASDSEGHSEDSDTQ------------SVSAHGQAGPHQQSHQESTRGRSAGRSGRSGSF 2414
+GH ED D S+ QA HQ E S G R S
Sbjct: 238 HRH--QGHEEDDDDDDDDDDDDDDDDVSIEYRHQAHRHQGHGIEEDEDVSDGHHHRDPSH 295
Query: 2415 LYQVSTHEQSESAHGRTGTSTGGRQGSHHKQARDSSRHSTSQEGQDTIHGHPGSSSGGRQ 2474
++ +HE+ ++ T G Q H+ R + S E + H G R
Sbjct: 296 RHR--SHEEDDNDDDDVSTEY-GHQAHRHQDHRKEEVEAVSGEHHHHVPDH--RHQGHRD 350
Query: 2475 GSHYEQLVDRSGHSGSHHSH------TTSQGRSDASHGHSGSRSASRQTRNDEQSGDGSR 2528
E + H G H H + GH + R ++DE+
Sbjct: 351 EEEDEDVSTERWHQGPQHVHHGLVDEEEEEEEITVQFGHYVASHQPRGHKSDEEDFQDEY 410
Query: 2529 HSGSRHHEASSRADSSGHSQVGQGQSEGPRTSRNWGSSFSQDSDSQGHSEDSERWSGSAS 2588
+ HH H +V + + E + S GH S R S
Sbjct: 411 KTEVPHHH---------HHRVPREEDE-------------EVSAELGHQAPSHRQSHQDE 448
Query: 2589 RNHHGSAQEQLRDGSRHPRSHQ--EDRAGHGHSADSSRQSGTRHTQTSSGGQAASSHEQA 2646
HG + +++ S HP H +DR+ H DS + + + G
Sbjct: 449 ETGHGQ-RGSIKEMSHHPPGHTVVKDRS-HLRKDDSEEE---KEKEEDPGSHEEDDESSE 503
Query: 2647 RSSAGERHGSHHQQSADSSRHSGIGHGQASSAVRDSGHRGYSGSQASDNEGHSEDSDTQS 2706
+ G HGS Q+ + GHG + + + + D E E+ D +
Sbjct: 504 QGEKGTHHGSRDQEDEEDEEE---GHGLSLNQEEE---------EEEDKEEEEEEEDEER 551
Query: 2707 VSAHGQAGS-----HQQSHQESARG 2726
+ G+ H + +E G
Sbjct: 552 REERAEVGAPLSPDHSEEEEEEEEG 576
Score = 77.0 bits (188), Expect = 3e-13
Identities = 117/632 (18%), Positives = 196/632 (31%), Gaps = 72/632 (11%)
Query: 3373 RDRSGGRSGRSGSFLYQVSTHEQSESAHGRTRTSTGRRQGSHH--EQARDSSRHSASQEG 3430
R+ S G +G S ++ H S H G H R+ S+E
Sbjct: 40 RNNSTGVAGLSEEASAELRHHLHSPRDHPDENKDVSTENGHHFWSHPDREKEDEDVSKEY 99
Query: 3431 QDTIRGHPGSSRR-GRQG-SHYEQSVDRSGHSGSHHSHTTSQGRSDASRGQS--GSRSAS 3486
+ GH + G +G S E + G + H H + A RS S
Sbjct: 100 GHLLPGHRSQDHKVGDEGVSGEEVFAEHGGQARGHRGHGSEDTEDSAEHRHHLPSHRSHS 159
Query: 3487 RQTRNDEQSGDGSRHSWSHHHEASTQADSSRHSQSGQGQSAGPRTSRNQGSSVSQDSDSQ 3546
Q ++++ S HHH + +G+ ++ + +
Sbjct: 160 HQDEDEDEVV-----SSEHHHHILRHGHRGHDGEDDEGE---------------EEEEEE 199
Query: 3547 GHSEDSERWSGSASRNHRGSAQEQSRDGSRHPTSHHEDRAGHGHSAESSRQSGTHHAENS 3606
E++ G + HRG E+ D S GH H S R G H ++
Sbjct: 200 EEEEEASTEYGHQAHRHRGHGSEEDEDVSD----------GHHHHGPSHRHQG-HEEDDD 248
Query: 3607 SGGQAASSHEQARSSAGERHGSHHQQSADSSRHSGIGHGQASSAVRDSGHRGSSGSQASD 3666
+ S RH +H RH G G + HR S S
Sbjct: 249 DDDDDDDDDDDDDVSIEYRHQAH--------RHQGHGIEEDEDVSDGHHHRDPSHRHRSH 300
Query: 3667 SEGHSEDSDTQSVSAHGQAGPHQQSHQESTRGRSAGRSGRSGSFLYQVSTHEQSESAHGR 3726
E ++D D + H QA HQ +E S +Q E+ +
Sbjct: 301 EEDDNDDDDVSTEYGH-QAHRHQDHRKEEVEAVSGEHHHHVPDHRHQGHRDEEEDEDVS- 358
Query: 3727 AGPSTGGRQGSRHEQARDSSRHSASQEGQDTIR-GH--PGSRRGGRQGSYHEQSVDRSGH 3783
+ QG +H +E + T++ GH + G + + +
Sbjct: 359 ---TERWHQGPQH--VHHGLVDEEEEEEEITVQFGHYVASHQPRGHKSDEEDFQDEYKTE 413
Query: 3784 SGSHHSHTTSQGRSDASHGQSGSRSAS-RETRNEEQSGDGSRHS--------------GS 3828
HH H + + + G ++ S R++ +E++G G R S
Sbjct: 414 VPHHHHHRVPREEDEEVSAELGHQAPSHRQSHQDEETGHGQRGSIKEMSHHPPGHTVVKD 473
Query: 3829 RHHEASTQADSSRHSQSGQGESAGSRRSRRQGSSVSQDSDSEAYPEDSERRSESASRNHH 3888
R H ++ + + G S QG + + E+ E S N
Sbjct: 474 RSHLRKDDSEEEKEKEEDPGSHEEDDESSEQGEKGTHHGSRDQEDEEDEEEGHGLSLNQE 533
Query: 3889 GSSREQSRDGSRHPGSSHRDTASHVQS--SPVQSDSSTAKEHGHFSSLSQDSAYHSGIQS 3946
E + R+ + V + SP S+ +E G + + + +
Sbjct: 534 EEEEEDKEEEEEEEDEERREERAEVGAPLSPDHSEEEEEEEEGLEEDEPRFTIIPNPLDR 593
Query: 3947 RGSPHSSSSYHYQSEGTERQKGQSGLVWRHGS 3978
R +SS E T Q Q ++ GS
Sbjct: 594 REEAGGASSEEESGEDTGPQDAQEYGNYQPGS 625
Score = 77.0 bits (188), Expect = 3e-13
Identities = 142/676 (21%), Positives = 199/676 (29%), Gaps = 119/676 (17%)
Query: 526 GRQGSHHEQSVNRSGHSGSHHSHTTSQGRSDASHGQSGSRSASRQTRNEEQSGD-GTRHS 584
G G E S H S H +G R+ +E+ S + G
Sbjct: 45 GVAGLSEEASAELRHHLHSPRDHPDENKDVSTENGHHFWSHPDREKEDEDVSKEYGHLLP 104
Query: 585 GSRHHEASSQADSSRHSQVGQGQSSGPRTSRNQGSSVSQDSDSQGHSEDSERWSGSASRN 644
G R + + +V R R GS ++DS H S R S +
Sbjct: 105 GHRSQDHKVGDEGVSGEEVFAEHGGQARGHRGHGSEDTEDSAEHRHHLPSHR-----SHS 159
Query: 645 HHGSAQEQSRDGSRHPRSHHEDRAGH-GHSADSSRKSGTRHTQNSSSGQAASSHEQARSS 703
H +++ H HH R GH GH D G + + AS+ ++
Sbjct: 160 HQDEDEDEVVSSEHH---HHILRHGHRGH--DGEDDEGEEEEEEEEEEEEASTEYGHQAH 214
Query: 704 AGERHGSRHQLQSADSSRHSGTGHGQASSAVRDSGHRGSSGSQATDSEGHSEDSDTQSVS 763
HGS +D H G H R GH D + +D D S+
Sbjct: 215 RHRGHGSEEDEDVSDGHHHHGPSH-------RHQGHEEDDDDD--DDDDDDDDDDDVSIE 265
Query: 764 GHGQAGHHQQSHQESARDRSGERSRRSGSFLYQVSTHKQSESSHGWTGPSTGVRQGSHHE 823
QA HQ E D S H + SH R SH E
Sbjct: 266 YRHQAHRHQGHGIEEDEDVS--------------DGHHHRDPSH---------RHRSHEE 302
Query: 824 QARDNSRHSASQDGQDTIRGHPGSSRRGRQGSHHEQSVDRSGHSGSHHSHTTSQGRSDAS 883
D+ D T GH R H ++ V+ SG HH H
Sbjct: 303 DDNDD-------DDVSTEYGHQAH----RHQDHRKEEVEAV--SGEHHHHVPDHRHQGH- 348
Query: 884 RGQSGSRSASRTTRNEEQSRDGSRHSGSRHHEASSHADISRHSQAGQGQSEGSRTSRRQG 943
R+EE+ D S R H+ H H + E + + G
Sbjct: 349 -------------RDEEEDEDVSTE---RWHQGPQHV----HHGLVDEEEEEEEITVQFG 388
Query: 944 SSVSQDSDSEGHSEDSERWSGSAS------RNHRGSAQEQSRHGSR-------HPRSHHE 990
V+ GH D E + +HR +E + H +SH +
Sbjct: 389 HYVASHQP-RGHKSDEEDFQDEYKTEVPHHHHHRVPREEDEEVSAELGHQAPSHRQSHQD 447
Query: 991 DRAGHGHSADSSRQSGTP--HAETSSGGQAASSHEQARSSPGERHGSRHQQSADSSR--- 1045
+ GHG S P H + E GS H++ +SS
Sbjct: 448 EETGHGQRGSIKEMSHHPPGHTVVKDRSHLRKDDSEEEKEKEEDPGS-HEEDDESSEQGE 506
Query: 1046 ---HSGIPRRQASSAVRDSGH---WGSSGSQASDSEGHSEESDTQSVSGHGQDG-PHQQS 1098
H G R Q + GH + D E EE D + + G P
Sbjct: 507 KGTHHG-SRDQEDEEDEEEGHGLSLNQEEEEEEDKEEEEEEEDEERREERAEVGAPLSPD 565
Query: 1099 HQESARDWSGGRSGRSGSFIYQVSTHEQSESAHGRTRTSTGRRQGSHHEQARDSSRHSAS 1158
H E + G F + ++ E A G + S E D+ A
Sbjct: 566 HSEEEEEEEEGLEEDEPRFTIIPNPLDRREEAGGAS---------SEEESGEDTGPQDAQ 616
Query: 1159 QEGQDTIRAHPGSRRG 1174
+ G PGS G
Sbjct: 617 EYG----NYQPGSLCG 628
Score = 76.6 bits (187), Expect = 5e-13
Identities = 113/586 (19%), Positives = 172/586 (29%), Gaps = 98/586 (16%)
Query: 3167 NEEQSGDSSRHSVSRHHEASTHADISR-HSQAVQGQSEGSRRSRRQGSSVSQDSDSEGHS 3225
N++ S ++ H S D+S+ + + G + +G S + G
Sbjct: 71 NKDVSTENGHHFWSHPDREKEDEDVSKEYGHLLPGHRSQDHKVGDEGVSGEEVFAEHGGQ 130
Query: 3226 EDSERWSGSA----SRNHRGSVQEQSRHGSRH-------PRSHHEDRAGHGHSA-DRSRQ 3273
R GS S HR + H + HH HGH D
Sbjct: 131 ARGHRGHGSEDTEDSAEHRHHLPSHRSHSHQDEDEDEVVSSEHHHHILRHGHRGHDGEDD 190
Query: 3274 SGTRHAETSSGGQAASSHEQARSSPGERHGSRHQQSADSSRHSGIPRGQASSAVRDSRHW 3333
G E + AS+ ++ HGS + H P RH
Sbjct: 191 EGEEEEEEEEEEEEASTEYGHQAHRHRGHGSEEDEDVSDGHHHHGP---------SHRHQ 241
Query: 3334 G-SSGSQASDSEGHSEESDTQSVSGHGQAGPHQQSHQESARDRSGGRSGRSGSFLYQVST 3392
G D + ++ D S+ QA HQ E D S G R S ++ +
Sbjct: 242 GHEEDDDDDDDDDDDDDDDDVSIEYRHQAHRHQGHGIEEDEDVSDGHHHRDPSHRHR--S 299
Query: 3393 HEQSESAHGRTRTSTGRR---------------QGSHHEQARDSSRHSASQEGQD----T 3433
HE+ ++ T G + G HH D E +D T
Sbjct: 300 HEEDDNDDDDVSTEYGHQAHRHQDHRKEEVEAVSGEHHHHVPDHRHQGHRDEEEDEDVST 359
Query: 3434 IRGHPGSSRRGR--------------QGSHYEQSVDRSGHSGS--------------HHS 3465
R H G Q HY S GH HH
Sbjct: 360 ERWHQGPQHVHHGLVDEEEEEEEITVQFGHYVASHQPRGHKSDEEDFQDEYKTEVPHHHH 419
Query: 3466 HTTSQGRSDASRGQSGSRSAS-RQTRNDEQSGDGSRHS---WSHHHEASTQADSSRHSQS 3521
H + + + G ++ S RQ+ DE++G G R S SHH T H +
Sbjct: 420 HRVPREEDEEVSAELGHQAPSHRQSHQDEETGHGQRGSIKEMSHHPPGHTVVKDRSHLRK 479
Query: 3522 GQGQSAGPRTSRNQGSSVSQDSDSQGHSEDSERWSGSASRNHRGSAQEQSRDGSRHPTSH 3581
+ ++ D H ED E S+ + +G + GSR
Sbjct: 480 DDSE-----------EEKEKEEDPGSHEEDDE----SSEQGEKG-----THHGSRDQEDE 519
Query: 3582 HEDRAGHGHSAESSRQSGTHHAENSSGGQAASSHEQARSSAGERHGSHHQQSADSSRHSG 3641
++ GHG S + E + + R+ G H + +
Sbjct: 520 EDEEEGHGLSLNQEEEEEEDKEEEEE--EEDEERREERAEVGAPLSPDHSEEEEEEEEGL 577
Query: 3642 IGHGQASSAVRDSGHRGSSGSQASDSEGHSEDSDTQSVSAHGQAGP 3687
+ + + R AS E ED+ Q +G P
Sbjct: 578 EEDEPRFTIIPNPLDRREEAGGASSEEESGEDTGPQDAQEYGNYQP 623
Score = 72.0 bits (175), Expect = 1e-11
Identities = 135/658 (20%), Positives = 200/658 (30%), Gaps = 130/658 (19%)
Query: 1934 WSGSASRNHLGSAWEQSRDGSRHPGSHHEDRAGHGHSADSSRQSGTRHTESSSRGQAASS 1993
W+G AS + +Q R + + G S ++S + RH S R
Sbjct: 14 WAGVASLLLPPAMTQQLRGDGLGFRNRNNSTGVAGLSEEASAE--LRHHLHSPRDHP-DE 70
Query: 1994 HEQARSSAGERHGSH--HQLQSADSSRHSGI---GHGQASSAVRDSGHRGYS-----GSQ 2043
++ + G SH + + D S+ G GH V D G G G Q
Sbjct: 71 NKDVSTENGHHFWSHPDREKEDEDVSKEYGHLLPGHRSQDHKVGDEGVSGEEVFAEHGGQ 130
Query: 2044 ASDSEGHSEDSDTQSVSAQGKAGPHQQSHKESARGQSGESSGRSGSFLYQVSTHEQSEST 2103
A GH + S + H SH+ + E S S H
Sbjct: 131 ARGHRGHGSEDTEDSAEHRH----HLPSHRSHSHQDEDEDEVVS-------SEHHHHILR 179
Query: 2104 HGQSAPSTGGRQGSHYDQAQDSSRHSASQEGQDTIRGHPGPSRGGRQGSHQEQSVDRSGH 2163
HG G G D+ ++ +E T GH G E D H
Sbjct: 180 HGHR-----GHDGED-DEGEEEEEEEEEEEEASTEYGHQAHRHRGHGSEEDEDVSDGHHH 233
Query: 2164 SGSHHSHTTSQGRSDASRGQSGSRSASRKTYDKEQSGDGSRHSGSHHHEASSWADSSRHS 2223
G H H QG + D + D S + H+A
Sbjct: 234 HGPSHRH---QGHEEDDDDDD----------DDDDDDDDDDVSIEYRHQA---------- 270
Query: 2224 LVGQGQSSGPRTSRPRGSSVSQDSD-SEGHSEDSERRSGSASRNHHGSAQEQSRDGSRHP 2282
R +G + +D D S+GH HH RD S
Sbjct: 271 ------------HRHQGHGIEEDEDVSDGH--------------HH-------RDPSHRH 297
Query: 2283 RSHHEDRAGHGHSAESSRQSGTHHAENSSGGQAASSHEQARSSAGERHGSHHQQSADSS- 2341
RSH ED + H ++ A S E RH H + D
Sbjct: 298 RSHEEDDNDDDDVSTEYGHQAHRHQDHRKEEVEAVSGEHHHHVPDHRHQGHRDEEEDEDV 357
Query: 2342 ----RHSG---IGHGQASSAVRDS------GHRGSS---GSQASDSEGHSEDSDTQSVSA 2385
H G + HG + GH +S SD E ++ T+
Sbjct: 358 STERWHQGPQHVHHGLVDEEEEEEEITVQFGHYVASHQPRGHKSDEEDFQDEYKTEVPHH 417
Query: 2386 HGQAGPHQQSHQESTRGRSAGRSGRSGSFLYQVSTHEQSESAHGRTGTSTGGRQGSHHK- 2444
H P ++ + S S R +H+ E+ HG+ G+ ++ SHH
Sbjct: 418 HHHRVPREEDEEVSAELGHQAPSHR--------QSHQDEETGHGQRGSI---KEMSHHPP 466
Query: 2445 -----QARDSSRHSTSQEGQDTIHGHPGSSSGGRQGSHYEQLVDRSGHSGSHHSHTTSQG 2499
+ R R S+E ++ PGS + S G G+HH +
Sbjct: 467 GHTVVKDRSHLRKDDSEEEKEK-EEDPGSHEEDDESS-------EQGEKGTHHGSRDQED 518
Query: 2500 RSDASHGHSGSRSASRQTRNDEQSGDGSRHSGSRHHEASSRAD-SSGHSQVGQGQSEG 2556
D GH S + + D++ + R A A S HS+ + + EG
Sbjct: 519 EEDEEEGHGLSLNQEEEEEEDKEEEEEEEDEERREERAEVGAPLSPDHSEEEEEEEEG 576
Score = 57.0 bits (136), Expect = 4e-07
Identities = 96/527 (18%), Positives = 170/527 (32%), Gaps = 69/527 (13%)
Query: 101 HRKHSHHDKHEDNKQEENKENRKRPSSLERRNNRKGNKGRSKSPRETGGKRHESSSEKKE 160
HR HSH D+ ED + R+ +G+ G + G+ E E++E
Sbjct: 155 HRSHSHQDEDEDEVVSSEHHHH------ILRHGHRGHDG-----EDDEGEEEEEEEEEEE 203
Query: 161 RKGYSPTHREEEYGKNHHNSSKKEKNKTENTRLGDNRKRLSER---LEEKEDNEEGVYDY 217
EYG H + E+ G + S R EE +D+++ D
Sbjct: 204 -------EASTEYGHQAHRHRGHGSEEDEDVSDGHHHHGPSHRHQGHEEDDDDDDDDDDD 256
Query: 218 ENTGRMTQKWIQSGHIATYYTIQDEAYDTTDSLLEENKIYERSRSSDGKSSSQVNRSRHE 277
++ ++ ++ H + I+++ D +D + S +RS HE
Sbjct: 257 DDDDDVSIEYRHQAHRHQGHGIEEDE-DVSD-------------GHHHRDPSHRHRS-HE 301
Query: 278 NTSQVPLQESRTRKRRGSRVSQDRDSEGHSEDSERHSGSASRNHHGSAWEQSRDGSRHPR 337
S + R R E + E H H G E+ + R
Sbjct: 302 EDDNDDDDVSTEYGHQAHRHQDHRKEEVEAVSGEHHHHVPDHRHQGHRDEEEDEDVSTER 361
Query: 338 SHDEDRASHGHSADSSRQSGTRHAETSSRGQTASSHE-QARSSPGERHGSGHQQSADSSR 396
H + H D + T G +SH+ + S E ++
Sbjct: 362 WHQGPQHVHHGLVDEEEE---EEEITVQFGHYVASHQPRGHKSDEEDFQDEYKTEVPHHH 418
Query: 397 HSATGRGQASSAVSDRGHRGSSGSQASDSE--GHSENSDTQSVSGH--GKAGLRQQSHQE 452
H R + ++ GH+ S Q+ E GH + + +S H G ++ +SH
Sbjct: 419 HHRVPREEDEEVSAELGHQAPSHRQSHQDEETGHGQRGSIKEMSHHPPGHTVVKDRSHL- 477
Query: 453 STRGRSGERSGRSGSSLYQVSTHEQPDSAHGRTGTSTGGRQGSHHEQARDSSRHSASQEG 512
R S + E P S +S G +G+HH +RD +EG
Sbjct: 478 -----------RKDDSEEEKEKEEDPGSHEEDDESSEQGEKGTHH-GSRDQEDEEDEEEG 525
Query: 513 QDTIRGHPGSSRGGRQGSHHEQSVNRSGHSGSHHSHTTSQGRSDASHGQSGSRSASRQTR 572
++ E+ R + R++ S S +
Sbjct: 526 HGLSLNQEEEEEEDKEEEEEEEDEER------------REERAEVGAPLSPDHSEEEEEE 573
Query: 573 NEEQSGDGTRHSGSRHHEASSQADSSRHSQVGQGQSSGPRTSRNQGS 619
E D R + + + S+ G+ +GP+ ++ G+
Sbjct: 574 EEGLEEDEPRFTIIPNPLDRREEAGGASSEEESGEDTGPQDAQEYGN 620
Score = 42.0 bits (97), Expect = 0.012
Identities = 30/122 (24%), Positives = 53/122 (43%), Gaps = 8/122 (6%)
Query: 98 GHKHRKHSHHDKHEDNKQEENKENRKRPSSLERRNNRKGNKGRSKSPRETGGKRHESSSE 157
GH K H + +D+++E+ KE + ++ +G KG G + E +
Sbjct: 467 GHTVVKDRSHLRKDDSEEEKEKEEDPGSHEEDDESSEQGEKG-----THHGSRDQEDEED 521
Query: 158 KKERKGYS-PTHREEEYGKNHHNSSKKEKNKTENTRLGDNRKRLSERLEEKEDNEEGVYD 216
++E G S EEE K + E+ + E +G + EE+E+ EEG+ +
Sbjct: 522 EEEGHGLSLNQEEEEEEDKEEEEEEEDEERREERAEVG--APLSPDHSEEEEEEEEGLEE 579
Query: 217 YE 218
E
Sbjct: 580 DE 581
Score = 41.2 bits (95), Expect = 0.021
Identities = 61/304 (20%), Positives = 112/304 (36%), Gaps = 49/304 (16%)
Query: 86 YESTRKENLPISGHKHRKHSHHDKHEDNKQEENKENRKRPSSLER-----RNNRKGNKGR 140
++ RKE + +H H +H+ ++ EE E+ S ER ++ G
Sbjct: 321 HQDHRKEEVEAVSGEHHHHVPDHRHQGHRDEEEDED----VSTERWHQGPQHVHHGLVDE 376
Query: 141 SKSPRETGGK------RHESSSEKKERKGYSPTHREEEYGKNHHNSSKKEKNKTENTRLG 194
+ E + H+ K + + + ++ E +HH+ +E+++ + LG
Sbjct: 377 EEEEEEITVQFGHYVASHQPRGHKSDEEDFQDEYK-TEVPHHHHHRVPREEDEEVSAELG 435
Query: 195 DNRKRLSERLEEKEDNEEGVYDYENTGRMTQKWIQSGHIATYYTIQDEAYDTTDSLLEEN 254
+ + +D E G + G + + S H + ++D ++ D EE
Sbjct: 436 ---HQAPSHRQSHQDEETG---HGQRGSIKE---MSHHPPGHTVVKDRSHLRKDDSEEEK 486
Query: 255 KIYE--RSRSSDGKSSSQVNRSRHENTSQVPLQESRTRKRRGSRVS--------QDRDSE 304
+ E S D +SS Q + H + QE + G +S +D++ E
Sbjct: 487 EKEEDPGSHEEDDESSEQGEKGTHHGSRD---QEDEEDEEEGHGLSLNQEEEEEEDKEEE 543
Query: 305 GHSEDSERHS-----GSASRNHHGSAWEQSRDG--SRHPR----SHDEDRASHGHSADSS 353
ED ER G+ H E+ +G PR + DR A S
Sbjct: 544 EEEEDEERREERAEVGAPLSPDHSEEEEEEEEGLEEDEPRFTIIPNPLDRREEAGGASSE 603
Query: 354 RQSG 357
+SG
Sbjct: 604 EESG 607
>gi|4758172 dentin matrix acidic phosphoprotein 1 isoform 1 precursor
[Homo sapiens]
Length = 513
Score = 91.7 bits (226), Expect = 1e-17
Identities = 122/546 (22%), Positives = 198/546 (36%), Gaps = 62/546 (11%)
Query: 982 SRHPRSHHED-RAGHGHSADSSRQSGTPHAETS--SGGQAASSHEQARSSPGERHGSRHQ 1038
+R+ + ED GH A Q+ TP E+S S G SS EQA P + S
Sbjct: 20 TRYQNNESEDSEEWKGHLA----QAPTPPLESSESSEGSKVSSEEQANEDPSDSTQSEEG 75
Query: 1039 QSADSSRHSGIPRRQASSAVRDSGHWGSSGSQASDSEGHSEESDTQSVSGHGQDGPHQQS 1098
+D ++ R +G + S + D + E+ G GP +
Sbjct: 76 LGSDDHQY----------IYRLAGGFSRSTGKGGDDKDDDEDDSGDDTFGDDDSGPGPKD 125
Query: 1099 HQESARDWSGGRSGRSGSFIYQVSTHEQSESAHGRTRTSTGRRQGSHHEQARDSSRHSAS 1158
QE GG S ++ + E S+ + S + Q S A+D++ S
Sbjct: 126 RQE------GGNS--------RLGSDEDSDDTIQASEESAPQGQDS----AQDTTSESRE 167
Query: 1159 QEGQDTIRAHPGSRRGGRQGSHHEQSVDRSGHSGSHHSHTTSQGRSDASHGQSGSRSASR 1218
+ +D + + P GG D + S S ++SHG GS
Sbjct: 168 LDNEDRVDSKP---EGG----------DSTQESESEEHWVGGGSDGESSHGD-GSELDDE 213
Query: 1219 QTRKDKQSGDGSRHSGSRHHEAASWADSSRHS--QVGQEQSSGSRTSRHQGSSVSQDSDS 1276
+ D S SR + A + S + Q + S GS+ H + + S
Sbjct: 214 GMQSDDPESIRSERGNSRMNSAGMKSKESGENSEQANTQDSGGSQLLEHPSRKIFRKSRI 273
Query: 1277 ERHSDDSERLSGSASRNHHGSSREQSRDGSRHPGFHQEDRASHGHSADSSRQSGTHHTES 1336
D SE + S E S SR G Q R S G S + S+++ +
Sbjct: 274 SEEDDRSELDDNNTMEEVKSDSTENSN--SRDTGLSQPRRDSKGDSQEDSKENLSQEESQ 331
Query: 1337 SSHGQAVSSHEQARSSPGERHGSRHQQSADSSRHSGIGHRQASSAVRDSGHRGSSGSQVT 1396
+ G + S ++A S E ++ SR G +S V D SS +
Sbjct: 332 NVDGPSSESSQEANLSSQENSSESQEEVVSESR--GDNPDPTTSYVEDQEDSDSSEEDSS 389
Query: 1397 NSEGHSEDSDTQSVSAHGQAGPHQQSHKESARGQSGESSGRSRSFLYQVSSHE-QSESTH 1455
++ HS+ S+++ A ++ +ES E+S SS E QSE +H
Sbjct: 390 HTLSHSK-SESREEQADSESSESLNFSEESPESPEDENSSSQEGLQSHSSSAESQSEESH 448
Query: 1456 GQTAPSTGGRQGSRHEQARNSSRHSASQDGQDTIRGHPGSSRGGRQGSYHEQSV----DR 1511
+ S + SR ++ NS+ +S + ++ SR +YH + + D
Sbjct: 449 SEEDDSDS-QDSSRSKEDSNSTESKSSSEEDGQLKNIEIESRKLTVDAYHNKPIGDQDDN 507
Query: 1512 SGHSGY 1517
GY
Sbjct: 508 DCQDGY 513
Score = 83.2 bits (204), Expect = 5e-15
Identities = 102/448 (22%), Positives = 160/448 (35%), Gaps = 30/448 (6%)
Query: 1590 QGSSVSQDRDSEGHSEDSERRSES-ASRNH---YGSAREQSRHGSRNPRSHQEDRASHGH 1645
+GS VS + + DS + E S +H Y A SR + +D G
Sbjct: 52 EGSKVSSEEQANEDPSDSTQSEEGLGSDDHQYIYRLAGGFSRSTGKGGDDKDDDEDDSGD 111
Query: 1646 SAESSRQSGTRHAETSSGGQAASSQEQARSSPGERHGSRHQQSADSSTDSGTGRRQ-DSS 1704
SG + GG + ++ + Q DS+ D+ + R+ D+
Sbjct: 112 DTFGDDDSGPGPKDRQEGGNSRLGSDEDSDDTIQASEESAPQGQDSAQDTTSESRELDNE 171
Query: 1705 VVGDSGNRGSSGSQASDSEGHSEESDTQSVSAHGQAGP-----HQQSHQESTRGQSGERS 1759
DS G +Q S+SE H + S+HG Q ES R + G
Sbjct: 172 DRVDSKPEGGDSTQESESEEHWVGGGSDGESSHGDGSELDDEGMQSDDPESIRSERGNSR 231
Query: 1760 GRSGSFLYQVSTHEQSESAHGRTGPSTGGRQRSRHEQARDSSRHSASQEGQDTIRGHPGS 1819
S + + E E++ +GG Q H + + S+E
Sbjct: 232 MNSAG----MKSKESGENSEQANTQDSGGSQLLEHPSRKIFRKSRISEE----------D 277
Query: 1820 SRGGRQGSHYEQSVDSSGHSGSHHSHT-TSQERSDVSRGQSGSRSVSRQTRNEKQSGDGS 1878
R ++ + V S S+ T SQ R D S+G S S ++ E Q+ DG
Sbjct: 278 DRSELDDNNTMEEVKSDSTENSNSRDTGLSQPRRD-SKGDSQEDSKENLSQEESQNVDGP 336
Query: 1879 RHSGSRHHEASSRADSSRHSQVGQGQSSGPRTSRNQGSSVSQDSDSQGHSEDSERWSGSA 1938
S+ SS+ +SS + +S G S V DS EDS S +
Sbjct: 337 SSESSQEANLSSQENSSESQEEVVSESRGDNPDPTT-SYVEDQEDSDSSEEDS---SHTL 392
Query: 1939 SRNHLGSAWEQSRDGSRHPGSHHEDRAGHGHSADSSRQSGTRHTESSSRGQAASSHEQAR 1998
S + S EQ+ S + E+ +SS Q G + SS+ Q+ SH +
Sbjct: 393 SHSKSESREEQADSESSESLNFSEESPESPEDENSSSQEGLQSHSSSAESQSEESHSEED 452
Query: 1999 SSAGERHGSHHQLQSADSSRHSGIGHGQ 2026
S + + ++ S+ S GQ
Sbjct: 453 DSDSQDSSRSKEDSNSTESKSSSEEDGQ 480
Score = 78.6 bits (192), Expect = 1e-13
Identities = 107/482 (22%), Positives = 171/482 (35%), Gaps = 37/482 (7%)
Query: 631 SEDSERWSGSASRNHHGSAQEQSRDGSRHPRSHHEDRAGHGHSADSSRKSGTRHTQNSSS 690
SEDSE W G ++ P E G S++ + S
Sbjct: 27 SEDSEEWKGHLAQ------------APTPPLESSESSEGSKVSSEEQANEDPSDSTQSEE 74
Query: 691 GQAASSHEQARSSAGERHGSRHQLQSADSSRHSGTGHGQASSAVRDSGHRGSSGSQATDS 750
G + H+ AG SR + D G + DSG + +S
Sbjct: 75 GLGSDDHQYIYRLAGGF--SRSTGKGGDDKDDDEDDSGDDTFGDDDSGPGPKDRQEGGNS 132
Query: 751 E-GHSEDSDTQSVSGHGQAGHHQQSHQESARD-RSGERSRRSGSFLYQVSTHKQSESSHG 808
G EDSD + A Q S Q++ + R + R S + ++SES
Sbjct: 133 RLGSDEDSDDTIQASEESAPQGQDSAQDTTSESRELDNEDRVDSKPEGGDSTQESESEEH 192
Query: 809 WTGPSTGVRQGSHHEQARDNSRHSASQDGQDTIRGHPGSSRRGRQGSHHEQSVDRSGHSG 868
W G G S H + D ++IR G+SR G +S SG
Sbjct: 193 WVGG--GSDGESSHGDGSELDDEGMQSDDPESIRSERGNSRMNSAGM-------KSKESG 243
Query: 869 SHHSHTTSQGRSDASRGQSGSRSASRTTRNEEQSRDGSRHSGSRHHEASSHADISRHSQA 928
+ +Q + + SR R +R E+ + E S + + +S+
Sbjct: 244 ENSEQANTQDSGGSQLLEHPSRKIFRKSRISEEDDRSELDDNNTMEEVKSDSTENSNSR- 302
Query: 929 GQGQSEGSRTSRRQGSSVSQDSDSEGHSEDSERWSGSASRNHRGSAQEQSRHGSRHPRSH 988
G S+ R S+ S+++ S+ S++ + S +S+ S+QE S S
Sbjct: 303 DTGLSQPRRDSKGDSQEDSKENLSQEESQNVDGPSSESSQEANLSSQENSSESQEEVVSE 362
Query: 989 HEDRAGHGHSADSSRQSGTPHAETSSGGQAASSHEQARSSPGERHGSRHQQSADS---SR 1045
G + D + S E S + SSH + S R +S++S S
Sbjct: 363 -----SRGDNPDPTT-SYVEDQEDSDSSEEDSSHTLSHSKSESREEQADSESSESLNFSE 416
Query: 1046 HSGIPRRQASSAVRDSGHWGSSGSQASDSEGHSEE--SDTQSVSGHGQDGPHQQSHQESA 1103
S +S+ ++ SS +++ E HSEE SD+Q S +D +S S
Sbjct: 417 ESPESPEDENSSSQEGLQSHSSSAESQSEESHSEEDDSDSQDSSRSKEDSNSTESKSSSE 476
Query: 1104 RD 1105
D
Sbjct: 477 ED 478
Score = 78.2 bits (191), Expect = 2e-13
Identities = 123/555 (22%), Positives = 208/555 (37%), Gaps = 120/555 (21%)
Query: 1095 HQQSHQESARDWSGGRSGRSGSFIYQVSTH--EQSESAHGRTRTSTGRRQGSHHEQARDS 1152
+Q + E + +W G + Q T E SES+ G ++ S+ + + S
Sbjct: 22 YQNNESEDSEEWKG--------HLAQAPTPPLESSESSEG-SKVSSEEQANEDPSDSTQS 72
Query: 1153 SRHSASQEGQDTIRAHPG-SRRGGRQGSHHEQSVDRSGHSGSHHSHTTSQGRSDASHGQS 1211
S + Q R G SR G+ G + D SG + G D+ G
Sbjct: 73 EEGLGSDDHQYIYRLAGGFSRSTGKGGDDKDDDEDDSGDD--------TFGDDDSGPGP- 123
Query: 1212 GSRSASRQTRKDKQSGDGSRHSGSRHHEAASWADSSRHSQVGQEQSSGSRTSRHQGSSVS 1271
KD+Q G SR S DS Q +E S QG +
Sbjct: 124 ----------KDRQEGGNSR--------LGSDEDSDDTIQASEE-------SAPQGQDSA 158
Query: 1272 QDSDSE-RHSDDSERLSGSASRNHHGSSREQSRDGSRHPGFHQEDRASHGHSADSSRQSG 1330
QD+ SE R D+ +R+ S+ G S ++S G + +SHG +
Sbjct: 159 QDTTSESRELDNEDRVD---SKPEGGDSTQESESEEHWVGGGSDGESSHGDGS------- 208
Query: 1331 THHTESSSHGQAVSSHEQARSSPGERHGSRHQQSADSSRHSGIGHRQASSAVRDSGHRGS 1390
E G E RS ER SR + S+ SG QA++ +DSG GS
Sbjct: 209 ----ELDDEGMQSDDPESIRS---ERGNSRMNSAGMKSKESGENSEQANT--QDSG--GS 257
Query: 1391 S-----------GSQVTNSEGHSEDSDTQSVSAHGQAGPHQQSHKESARGQSG-ESSGRS 1438
S+++ + SE D ++ + +++ Q +S G S
Sbjct: 258 QLLEHPSRKIFRKSRISEEDDRSELDDNNTMEEVKSDSTENSNSRDTGLSQPRRDSKGDS 317
Query: 1439 RSFLYQVSSHEQSESTHGQTAPSTGGRQGSRHEQARNSSRHSASQDGQDTIRGHPGSSRG 1498
+ + S E+S++ G ++ S+ ++A SS+ ++S+ ++ + SRG
Sbjct: 318 QEDSKENLSQEESQNVDGPSSESS--------QEANLSSQENSSESQEEVV----SESRG 365
Query: 1499 GRQG---SYHEQSVDRSGHSGYHHSHTTPQGRSDASHGQSGPRSASRQTRNEEQSGDGSR 1555
SY E D + D+SH S +S SR+ + + +S +
Sbjct: 366 DNPDPTTSYVEDQED------------SDSSEEDSSHTLSHSKSESREEQADSESSESLN 413
Query: 1556 HSGSRHHEPSTRAGSSRHSQVGQGESAGSKTSRRQGSSVSQDRDSEGHSEDSERRSESAS 1615
S P + E++ S+ + SS ++ + E HSE+ + S+ +S
Sbjct: 414 FSEESPESP-------------EDENSSSQEGLQSHSSSAESQSEESHSEEDDSDSQDSS 460
Query: 1616 RNHYGSAREQSRHGS 1630
R+ S +S+ S
Sbjct: 461 RSKEDSNSTESKSSS 475
Score = 77.0 bits (188), Expect = 3e-13
Identities = 114/490 (23%), Positives = 177/490 (36%), Gaps = 49/490 (10%)
Query: 1230 SRHSGSRHHEAASW----ADSSRHSQVGQEQSSGSRTSRHQGS----SVSQDSDSERHSD 1281
+R+ + ++ W A + E S GS+ S + + S S S+ SD
Sbjct: 20 TRYQNNESEDSEEWKGHLAQAPTPPLESSESSEGSKVSSEEQANEDPSDSTQSEEGLGSD 79
Query: 1282 DSE---RLSGSASRN--HHGSSREQSRDGSRHPGFHQEDRASHGHSADSSRQSGTHHTES 1336
D + RL+G SR+ G ++ D S F +D RQ G +
Sbjct: 80 DHQYIYRLAGGFSRSTGKGGDDKDDDEDDSGDDTFGDDDSGP----GPKDRQEGGNSRLG 135
Query: 1337 SSHGQAVSSHEQARSSPGERHGSRHQQSADSSRHSGIGHRQASSAVR-DSGHRGSSGSQV 1395
S + S+P Q DS++ + R+ + R DS G +Q
Sbjct: 136 SDEDSDDTIQASEESAP---------QGQDSAQDTTSESRELDNEDRVDSKPEGGDSTQE 186
Query: 1396 TNSEGHSEDSDTQSVSAHGQAGPHQQSHKESARGQSGESS-GRSRSFLYQVSSHEQSEST 1454
+ SE H + S+HG +S +S S G SR + S E E++
Sbjct: 187 SESEEHWVGGGSDGESSHGDGSELDDEGMQSDDPESIRSERGNSRMNSAGMKSKESGENS 246
Query: 1455 HGQTAPSTGGRQGSRHEQARNSSRHSASQDGQDTIRGHPGSSRGGRQGSYHEQSVDRSGH 1514
+GG Q H +R R S + D S + E D + +
Sbjct: 247 EQANTQDSGGSQLLEHP-SRKIFRKSRISEEDDR-------SELDDNNTMEEVKSDSTEN 298
Query: 1515 SGYHHSHTTPQGRSDASHGQSGPRSASRQTRNEEQSGDGSRHSGSRHHEPSTRAGSSRHS 1574
S + + Q R D S G S S ++ E Q+ DG S+ S++ SS
Sbjct: 299 SNSRDTGLS-QPRRD-SKGDSQEDSKENLSQEESQNVDGPSSESSQEANLSSQENSSESQ 356
Query: 1575 QVGQGESAGSKTSRRQGSSVSQDRDSEGHSEDSERRSESASRNHYGSAREQSRHGSRNPR 1634
+ ES G S V DS+ EDS S + S + S EQ+ S
Sbjct: 357 EEVVSESRGDNPDPTT-SYVEDQEDSDSSEEDS---SHTLSHSKSESREEQADSESSESL 412
Query: 1635 SHQEDRASHGHSAESSRQSGTRHAETSSGGQAASSQEQARSSPGERHGSRHQQSADSSTD 1694
+ E+ SS Q G + ++S++ Q+ S E S Q S+ S D
Sbjct: 413 NFSEESPESPEDENSSSQEGLQ-------SHSSSAESQSEESHSEEDDSDSQDSSRSKED 465
Query: 1695 SGTGRRQDSS 1704
S + + SS
Sbjct: 466 SNSTESKSSS 475
Score = 76.6 bits (187), Expect = 5e-13
Identities = 104/456 (22%), Positives = 171/456 (37%), Gaps = 55/456 (12%)
Query: 3282 SSGGQAASSHEQARSSPGERHGSRHQQSADSSRHSGIPRGQASSAVRDSRHWGSSGSQAS 3341
SS G SS EQA P + ++ ++ S H I R A SR G G
Sbjct: 50 SSEGSKVSSEEQANEDPSD--STQSEEGLGSDDHQYIYR----LAGGFSRSTGKGGDDKD 103
Query: 3342 DSEGHSEESDTQSVSGHGQAGPHQQSHQESARDRSGGRSGRSGSFLYQVSTHEQSESAHG 3401
D E S + G +GP + QE R G S Q S +
Sbjct: 104 DDEDDSGDD----TFGDDDSGPGPKDRQEGGNSRLG--SDEDSDDTIQASEESAPQGQDS 157
Query: 3402 RTRTSTGRRQGSHHE------QARDSSRHSASQE-----GQDTIRGH------------- 3437
T++ R+ + + + DS++ S S+E G D H
Sbjct: 158 AQDTTSESRELDNEDRVDSKPEGGDSTQESESEEHWVGGGSDGESSHGDGSELDDEGMQS 217
Query: 3438 --PGSSRRGRQGSHYEQSVDRSGHSGSHHSHTTSQGRSDASRGQSGSRSASRQTRNDEQS 3495
P S R R S + +S SG + +Q + + SR R++R E+
Sbjct: 218 DDPESIRSERGNSRMNSAGMKSKESGENSEQANTQDSGGSQLLEHPSRKIFRKSRISEE- 276
Query: 3496 GDGSRHSWSHHHEASTQADSSRHSQSGQ-GQSAGPRTSRNQGSSVSQDSDSQGHSEDSER 3554
D ++ ++DS+ +S S G S R S+ S+++ SQ S++ +
Sbjct: 277 -DDRSELDDNNTMEEVKSDSTENSNSRDTGLSQPRRDSKGDSQEDSKENLSQEESQNVDG 335
Query: 3555 WSGSASRNHRGSAQEQSRDGSRH------------PTSHHEDRAGHGHSAESSRQSGTHH 3602
S +S+ S+QE S + TS+ ED+ S E S + +H
Sbjct: 336 PSSESSQEANLSSQENSSESQEEVVSESRGDNPDPTTSYVEDQEDSDSSEEDSSHTLSHS 395
Query: 3603 AENSSGGQAASSHEQARSSAGERHGSHHQQSADSSRHSGIGHGQASSAVRDSGHRGSSGS 3662
S QA S ++ + + E S +++ SS+ H ++ + + H S
Sbjct: 396 KSESREEQADSESSESLNFSEESPESPEDENS-SSQEGLQSHSSSAESQSEESHSEEDDS 454
Query: 3663 QASDSEGHSEDSD-TQSVSAHGQAGPHQQSHQESTR 3697
+ DS EDS+ T+S S+ + G + ES +
Sbjct: 455 DSQDSSRSKEDSNSTESKSSSEEDGQLKNIEIESRK 490
Score = 76.3 bits (186), Expect = 6e-13
Identities = 110/546 (20%), Positives = 194/546 (35%), Gaps = 64/546 (11%)
Query: 219 NTGRMTQKWIQSGHIATYYTIQDEAYDTTDSLLEENKIYERSRSSDGKSSSQ-VNRSRHE 277
N +++W GH+A T E+ ++++ ++ SD S + + H+
Sbjct: 25 NESEDSEEW--KGHLAQAPTPPLESSESSEGSKVSSEEQANEDPSDSTQSEEGLGSDDHQ 82
Query: 278 NTSQVPLQESRTRKRRGSRVSQDRDSEGHSEDSERHSGSASRNHHGSAWEQSRDGSRHPR 337
++ SR+ + G D D G + SG ++ ++G
Sbjct: 83 YIYRLAGGFSRSTGKGGDDKDDDEDDSGDDTFGDDDSGPGPKDR--------QEGGNSRL 134
Query: 338 SHDEDRASHGHSADSSRQSGTRHAE-TSSRGQTASSHEQARSSPGERHGSGHQQSADSSR 396
DED +++ S G A+ T+S + + ++ S P G Q ++S
Sbjct: 135 GSDEDSDDTIQASEESAPQGQDSAQDTTSESRELDNEDRVDSKP---EGGDSTQESESEE 191
Query: 397 HSATGRGQASSAVSDRGHRGSSGSQASDSEG-HSENSDTQSVSGHGKAGLRQQSHQESTR 455
H G S+ D G Q+ D E SE +++ S
Sbjct: 192 HWVGGGSDGESSHGDGSELDDEGMQSDDPESIRSERGNSRMNS----------------- 234
Query: 456 GRSGERSGRSGSSLYQVSTHEQPDSAHGRTGTSTGGRQGSHHEQARDSSRHSASQEGQDT 515
+G +S SG + Q +T + +GG Q H + + S+E
Sbjct: 235 --AGMKSKESGENSEQANTQD------------SGGSQLLEHPSRKIFRKSRISEE---- 276
Query: 516 IRGHPGSSRGGRQGSHHEQSVNRSGHSGSHHSHT-TSQGRSDASHGQSGSRSASRQTRNE 574
R ++ + V S+ T SQ R D S G S S ++ E
Sbjct: 277 ------DDRSELDDNNTMEEVKSDSTENSNSRDTGLSQPRRD-SKGDSQEDSKENLSQEE 329
Query: 575 EQSGDGTRHSGSRHHEASSQADSSRHSQVGQGQSSGPRTSRNQGSSVSQDSDSQGHSEDS 634
Q+ DG S+ SSQ +SS + +S G S V DS EDS
Sbjct: 330 SQNVDGPSSESSQEANLSSQENSSESQEEVVSESRGDNPDPTT-SYVEDQEDSDSSEEDS 388
Query: 635 ERWSGSASRNHHGSAQEQSRDGSRHPRSHHEDRAGHGHSADSSRKSGTRHTQNSSSGQAA 694
S + S + S +EQ+ S + E+ +SS + G + +S+ Q+
Sbjct: 389 ---SHTLSHSKSESREEQADSESSESLNFSEESPESPEDENSSSQEGLQSHSSSAESQSE 445
Query: 695 SSHEQARSSAGERHGSRHQLQSADSSRHSGTGHGQASSAVRDSGHRGSSGSQATDSEGHS 754
SH + S + + ++ S+ S GQ + + + + + G
Sbjct: 446 ESHSEEDDSDSQDSSRSKEDSNSTESKSSSEEDGQLKN-IEIESRKLTVDAYHNKPIGDQ 504
Query: 755 EDSDTQ 760
+D+D Q
Sbjct: 505 DDNDCQ 510
Score = 75.5 bits (184), Expect = 1e-12
Identities = 118/525 (22%), Positives = 195/525 (37%), Gaps = 83/525 (15%)
Query: 1954 SRHPGSHHED-RAGHGHSADSSRQSGTRHTESS--SRGQAASSHEQARSSAGERHGSHHQ 2010
+R+ + ED GH A Q+ T ESS S G SS EQA +
Sbjct: 20 TRYQNNESEDSEEWKGHLA----QAPTPPLESSESSEGSKVSSEEQANEDPSD------- 68
Query: 2011 LQSADSSRHSGIGHGQASSAVRDSGHRGYSGSQASDSEGHSEDSDTQSVSAQGKAGPHQQ 2070
+ G+G R +G S + D + ED +GP +
Sbjct: 69 ----STQSEEGLGSDDHQYIYRLAGGFSRSTGKGGDDKDDDEDDSGDDTFGDDDSGPGPK 124
Query: 2071 SHKESARGQSGESSGRSGSFLYQVSTHEQSESTHGQSAPSTGGRQGSHYDQAQDSSRHSA 2130
+E + G T + SE +SAP QG D AQD++ S
Sbjct: 125 DRQEGGNSRLGSDEDSD-------DTIQASE----ESAP-----QGQ--DSAQDTTSESR 166
Query: 2131 SQEGQDTIRGHPGPSRGGRQGSHQEQSVDRSGHSGSHH---SHTTSQG-RSD------AS 2180
+ +D + P ++ +E V S H S +G +SD +
Sbjct: 167 ELDNEDRVDSKPEGGDSTQESESEEHWVGGGSDGESSHGDGSELDDEGMQSDDPESIRSE 226
Query: 2181 RGQSGSRSASRKTYDKEQSGDGSRHSGSHHHEASSWADSSRHSLVGQGQSS--GPRTSRP 2238
RG S SA K+ ++SG+ S + + S + + + + S R+
Sbjct: 227 RGNSRMNSAGMKS---KESGENSEQANTQDSGGSQLLEHPSRKIFRKSRISEEDDRSELD 283
Query: 2239 RGSSVSQ-DSDSEGHSEDSERRSGSASRNHHGSAQEQSRDGSRHPRSHHEDRAGHGHSAE 2297
+++ + SDS +S + R+ G +QE S++ S + D G S+E
Sbjct: 284 DNNTMEEVKSDSTENSNSRDTGLSQPRRDSKGDSQEDSKENLSQEESQNVD----GPSSE 339
Query: 2298 SSRQSGTHHAENSSGGQAASSHEQARSSAGERHGSHHQQSADSSRHSGIGHGQASSAVRD 2357
SS+++ ENSS Q E +R + S+ + DS S+ D
Sbjct: 340 SSQEANLSSQENSSESQEEVVSE-SRGDNPDPTTSYVEDQEDSD-----------SSEED 387
Query: 2358 SGHRGS-SGSQASDSEGHSEDSDTQSVSAHGQAGPHQQSHQESTRGRSAGRSGRSGSFLY 2416
S H S S S++ + + SE S++ + S P ++ S + G +
Sbjct: 388 SSHTLSHSKSESREEQADSESSESLNFSEESPESPEDENS-----------SSQEGLQSH 436
Query: 2417 QVSTHEQSESAHGRTGTSTGGRQGSHHKQARDS--SRHSTSQEGQ 2459
S QSE +H S + S K+ +S S+ S+ ++GQ
Sbjct: 437 SSSAESQSEESHSEEDDS-DSQDSSRSKEDSNSTESKSSSEEDGQ 480
Score = 75.1 bits (183), Expect = 1e-12
Identities = 93/493 (18%), Positives = 170/493 (34%), Gaps = 55/493 (11%)
Query: 2745 HEQSESSHGWTG-----PSTRGRQGSRHEQAQDSSRHSASQDGQDTIRGHPGSSRGGRQG 2799
+ +SE S W G P+ E ++ SS A++D D+ + G Q
Sbjct: 24 NNESEDSEEWKGHLAQAPTPPLESSESSEGSKVSSEEQANEDPSDSTQSEEGLGSDDHQY 83
Query: 2800 YHHEHSVDSSGHSGSHHSHTTSQGRSDASRGQSGSRSASRTTRNEEQSGDGSRHSGSRHH 2859
+ S +T +G D + S ++ GD G +
Sbjct: 84 IYR---------LAGGFSRSTGKGGDDKDDDEDDS--------GDDTFGDDDSGPGPKDR 126
Query: 2860 EASTHADISRHSQAVQGQSEGSRRSRRQGSSVSQDSDSEGHSEDSERWSGSASRNHHGSA 2919
+ ++ + + + S S QG +QD+ SE D+E S +
Sbjct: 127 QEGGNSRLGSDEDS-DDTIQASEESAPQGQDSAQDTTSESRELDNEDRVDSKPEGGDSTQ 185
Query: 2920 QEQLRDGSRHPRSHQEDRAGHGHSADSSRQSGTRHTQTSSGGQAASSHEQARSSAGERH- 2978
+ + +E G G +SS G+ + G + E RS G
Sbjct: 186 ESE----------SEEHWVGGGSDGESSHGDGS---ELDDEGMQSDDPESIRSERGNSRM 232
Query: 2979 ---GSHHQQSADSSRHSGIGHGQASSAVRDSGHRGYSGSQASDNEGHSEDSDTQSVSAHG 3035
G ++S ++S + S + + + S+ S+ + SE D ++
Sbjct: 233 NSAGMKSKESGENSEQANTQDSGGSQLLEHPSRKIFRKSRISEEDDRSELDDNNTMEEVK 292
Query: 3036 QAGSHQQSHQESARGRSGETSGHSGSFLYQVSTHEQSESSHGWTGPSTRGRQGSRHEQAQ 3095
+ + +++ G S G + E S GPS+ Q +A
Sbjct: 293 SDSTENSNSRDT--GLSQPRRDSKGDSQEDSKENLSQEESQNVDGPSSESSQ-----EAN 345
Query: 3096 DSSRHSASQYGQDTIRGHPGSSRGGRQGYHHEHSVDSSGHSGSHHSHTTSQGRSDASRGQ 3155
SS+ ++S+ ++ + G + Y + S S SHT S +S++ Q
Sbjct: 346 LSSQENSSESQEEVVSESRGDNPDPTTSYVEDQEDSDSSEEDS--SHTLSHSKSESREEQ 403
Query: 3156 SGSRSASRTTRNEEQ------SGDSSRHSVSRHHEASTHADISRHSQAVQGQSEGSRRSR 3209
+ S S+ +EE SS+ + H ++ HS+ S+ S RS+
Sbjct: 404 ADSESSESLNFSEESPESPEDENSSSQEGLQSHSSSAESQSEESHSEEDDSDSQDSSRSK 463
Query: 3210 RQGSSVSQDSDSE 3222
+S S SE
Sbjct: 464 EDSNSTESKSSSE 476
Score = 75.1 bits (183), Expect = 1e-12
Identities = 100/490 (20%), Positives = 172/490 (35%), Gaps = 48/490 (9%)
Query: 2577 SEDSERWSGSASRNHHGSAQEQLRDGSRHPRSHQEDRAGHGHSADSSRQSGTRHTQTSSG 2636
SEDSE W G L P E G S++ + S
Sbjct: 27 SEDSEEWKG------------HLAQAPTPPLESSESSEGSKVSSEEQANEDPSDSTQSEE 74
Query: 2637 GQAASSHEQARSSAGE------RHGSHHQQSADSSRHSGIGHGQASSAVRDSGHRGYSGS 2690
G + H+ AG + G D S G + +D G S
Sbjct: 75 GLGSDDHQYIYRLAGGFSRSTGKGGDDKDDDEDDSGDDTFGDDDSGPGPKDRQEGGNS-- 132
Query: 2691 QASDNEGHSEDSDTQSVSAHGQAGSHQQSHQES-ARGRSGETSGHSGSFLYQVSTHEQSE 2749
G EDSD ++ A Q S Q++ + R + S + ++SE
Sbjct: 133 ----RLGSDEDSDDTIQASEESAPQGQDSAQDTTSESRELDNEDRVDSKPEGGDSTQESE 188
Query: 2750 SSHGWTGPSTRGRQGSRHEQAQDSSRHSASQDGQDTIRGHPGSSRGGRQGYHHEHSVDSS 2809
S W G + G S H + D ++IR G+SR G + S ++S
Sbjct: 189 SEEHWVGGGSDGE--SSHGDGSELDDEGMQSDDPESIRSERGNSRMNSAGMKSKESGENS 246
Query: 2810 GHSGSHHSHTTSQGRSDASRGQSGSRSASRTTRNEEQSGDGSRHSGSRHHEASTHADISR 2869
+ + S + + + SR + R+E + S E S D
Sbjct: 247 EQANTQDSGGSQLLEHPSRKIFRKSRISEEDDRSELDDNNTMEEVKSDSTENSNSRDTGL 306
Query: 2870 HSQAVQGQSEGSRRSRRQGSSVSQDSDSEGHSEDSERWSGSASRNHHGSAQEQLRDGSRH 2929
SQ + S+ ++ S + + +G S +S + + +S+ + +QE++ SR
Sbjct: 307 -SQPRRDSKGDSQEDSKENLSQEESQNVDGPSSESSQEANLSSQENSSESQEEVVSESRG 365
Query: 2930 PR-----SHQEDRAGHGHSADSSRQSGTRHTQTSSGGQAASSHEQARSSAGERHGSHHQQ 2984
S+ ED+ +DSS + + T S ++ S EQA S + E
Sbjct: 366 DNPDPTTSYVEDQ----EDSDSSEEDSSH---TLSHSKSESREEQADSESSE-------- 410
Query: 2985 SADSSRHSGIGHGQASSAVRDSGHRGYSGSQASDNEGHSEDSDTQSVSAHGQAGSHQQSH 3044
S + S S +S+ ++ S +++ E HSE+ D+ S + +
Sbjct: 411 SLNFSEESPESPEDENSSSQEGLQSHSSSAESQSEESHSEEDDSDSQDSSRSKEDSNSTE 470
Query: 3045 QESARGRSGE 3054
+S+ G+
Sbjct: 471 SKSSSEEDGQ 480
Score = 73.9 bits (180), Expect = 3e-12
Identities = 97/452 (21%), Positives = 161/452 (35%), Gaps = 46/452 (10%)
Query: 1334 TESSSHGQAVSSHEQARSSPGERHGSRHQQSADS-----------SRHSGIGHRQASSAV 1382
+ SS G VSS EQA P + S +D SR +G G
Sbjct: 47 SSESSEGSKVSSEEQANEDPSDSTQSEEGLGSDDHQYIYRLAGGFSRSTGKGGDDKDDDE 106
Query: 1383 RDSGHR---------GSSGSQVTNSE--GHSEDSDTQSVSAHGQAGPHQQSHKESARGQS 1431
DSG G Q + G EDSD ++ A ++ P Q + +S
Sbjct: 107 DDSGDDTFGDDDSGPGPKDRQEGGNSRLGSDEDSD-DTIQASEESAPQGQDSAQDTTSES 165
Query: 1432 GESSGRSRSFLYQVSSHEQSESTHGQTAPSTGGRQGSRHEQARNSSRHSASQDGQDTIRG 1491
E R ES + G S H D ++IR
Sbjct: 166 RELDNEDRVDSKPEGGDSTQESESEEHWVGGGSDGESSHGDGSELDDEGMQSDDPESIRS 225
Query: 1492 HPGSSRGGRQGSYHEQSVDRSGHSGYHHSHTTPQGRSDASHGQSGPRSASRQTRNEEQSG 1551
G+SR G ++S + S ++T G S S R R++R E+
Sbjct: 226 ERGNSRMNSAGMKSKESGENS-----EQANTQDSGGSQLLEHPS--RKIFRKSRISEEDD 278
Query: 1552 DGSRHSGSRHHE---PSTRAGSSRH---SQVGQGESAGSKTSRRQGSSVSQDRDSEGHSE 1605
+ E ST +SR SQ + S+ ++ S + ++ +G S
Sbjct: 279 RSELDDNNTMEEVKSDSTENSNSRDTGLSQPRRDSKGDSQEDSKENLSQEESQNVDGPSS 338
Query: 1606 DSERRSESASRNHYGSAREQSRHGSRNPRSHQEDRASHGHSAESSRQSGTRHAETSSGGQ 1665
+S + + +S+ + ++E+ SR + + S+ E S S + T S +
Sbjct: 339 ESSQEANLSSQENSSESQEEVVSESRG--DNPDPTTSYVEDQEDSDSSEEDSSHTLSHSK 396
Query: 1666 AASSQEQARSSPGERHGSRHQQSADSSTDSGTGRRQDSSVVGDSGNRGSSGSQASDSEGH 1725
+ S +EQA S E S + S +S ++S + SS +++ E H
Sbjct: 397 SESREEQADSESSE--------SLNFSEESPESPEDENSSSQEGLQSHSSSAESQSEESH 448
Query: 1726 SEESDTQSVSAHGQAGPHQQSHQESTRGQSGE 1757
SEE D+ S + + +S+ + G+
Sbjct: 449 SEEDDSDSQDSSRSKEDSNSTESKSSSEEDGQ 480
Score = 73.2 bits (178), Expect = 5e-12
Identities = 101/487 (20%), Positives = 165/487 (33%), Gaps = 44/487 (9%)
Query: 2901 SEDSERWSGSASRNHHGSAQEQLRDGSRHPRSHQEDRAGHGHSADSSRQSGTRHTQTSSG 2960
SEDSE W G L P E G S++ + S
Sbjct: 27 SEDSEEWKG------------HLAQAPTPPLESSESSEGSKVSSEEQANEDPSDSTQSEE 74
Query: 2961 GQAASSHEQARSSAGE------RHGSHHQQSADSSRHSGIGHGQASSAVRDSGHRGYSGS 3014
G + H+ AG + G D S G + +D G S
Sbjct: 75 GLGSDDHQYIYRLAGGFSRSTGKGGDDKDDDEDDSGDDTFGDDDSGPGPKDRQEGGNS-- 132
Query: 3015 QASDNEGHSEDSDTQSVSAHGQAGSHQQSHQES-ARGRSGETSGHSGSFLYQVSTHEQSE 3073
G EDSD ++ A Q S Q++ + R + S + ++SE
Sbjct: 133 ----RLGSDEDSDDTIQASEESAPQGQDSAQDTTSESRELDNEDRVDSKPEGGDSTQESE 188
Query: 3074 SSHGWTGPSTRGRQGSRHEQAQDSSRHSASQYGQDTIRGHPGSSRGGRQGYHHEHSVDSS 3133
S W G + G S H + ++IR G+SR G S
Sbjct: 189 SEEHWVGGGSDGE--SSHGDGSELDDEGMQSDDPESIRSERGNSRMNSAGM-------KS 239
Query: 3134 GHSGSHHSHTTSQGRSDASRGQSGSRSASRTTRNEEQSGDSSRHSVSRHHEASTHADISR 3193
SG + +Q + + SR R +R E+ S + E + + +
Sbjct: 240 KESGENSEQANTQDSGGSQLLEHPSRKIFRKSRISEEDDRSELDDNNTMEEVKSDSTENS 299
Query: 3194 HSQAVQGQSEGSRRSRRQGSSVSQDSDSEGHSEDSERWSGSASRNHRGSVQEQSRHGSRH 3253
+S+ G S+ R S+ S+++ S+ S++ + S +S+ S QE S
Sbjct: 300 NSRDT-GLSQPRRDSKGDSQEDSKENLSQEESQNVDGPSSESSQEANLSSQENSSESQEE 358
Query: 3254 PRSHHEDRAGHGHSADRSRQSGTRHAETSSGGQAASSHEQARSSPGERHGSRHQQSADS- 3312
S G + D + S E S + SSH + S R +S++S
Sbjct: 359 VVSE-----SRGDNPDPTT-SYVEDQEDSDSSEEDSSHTLSHSKSESREEQADSESSESL 412
Query: 3313 --SRHSGIPRGQASSAVRDSRHWGSSGSQASDSEGHSEESDTQSVSGHGQAGPHQQSHQE 3370
S S +S+ ++ SS +++ E HSEE D+ S + +
Sbjct: 413 NFSEESPESPEDENSSSQEGLQSHSSSAESQSEESHSEEDDSDSQDSSRSKEDSNSTESK 472
Query: 3371 SARDRSG 3377
S+ + G
Sbjct: 473 SSSEEDG 479
Score = 72.8 bits (177), Expect = 7e-12
Identities = 102/451 (22%), Positives = 166/451 (36%), Gaps = 39/451 (8%)
Query: 2156 QSVDRSGHSGSHHSHTTSQGRSDASRGQSGSRSASRKTYDKEQSGDGSRHSGSHHHEASS 2215
+S + S S ++ SD+++ + G S + Y +G SR +G +
Sbjct: 46 ESSESSEGSKVSSEEQANEDPSDSTQSEEGLGSDDHQ-YIYRLAGGFSRSTGKGGDDKDD 104
Query: 2216 WADSSRHSLVGQGQSSGPRTSRPRGSSVSQDSDSEGHSEDSERRSGSASRNHHGSAQEQS 2275
D S G S R G + SD + S+D+ + S ++ SAQ+ +
Sbjct: 105 DEDDSGDDTFGDDDSGPGPKDRQEGGNSRLGSDED--SDDTIQASEESAPQGQDSAQDTT 162
Query: 2276 RDGSRHPRSHHEDRAGHGHSAESSRQSGTHHAENSSGGQAASSHEQARSSAGERHGSHHQ 2335
+ D G + +S H S G+ SSH E S
Sbjct: 163 SESRELDNEDRVDSKPEGGDSTQESESEEHWVGGGSDGE--SSHGDGSELDDEGMQSDDP 220
Query: 2336 QSADSSRHSGIGHGQASSAVRDSGHRGSSGSQASDSEGHSEDSDTQSVSAHGQAGPHQQS 2395
+S S R G+ + +SA S G + QA+ ++DS + H P ++
Sbjct: 221 ESIRSER----GNSRMNSAGMKSKESGENSEQAN-----TQDSGGSQLLEH----PSRKI 267
Query: 2396 HQESTRGRSAGRSGRSGSFLYQVSTHEQSESAHGR-TGTSTGGRQGSHHKQARDSSRHST 2454
++S RS + + + +E+++ R TG S R Q + S+ +
Sbjct: 268 FRKSRISEEDDRSELDDNNTMEEVKSDSTENSNSRDTGLSQPRRDSKGDSQ--EDSKENL 325
Query: 2455 SQEGQDTIHGHPGSSS-----GGRQGSHYEQLVDRSGHSGSHHSHTTS---------QGR 2500
SQE + G SS ++ S Q S G + TTS
Sbjct: 326 SQEESQNVDGPSSESSQEANLSSQENSSESQEEVVSESRGDNPDPTTSYVEDQEDSDSSE 385
Query: 2501 SDASHGHSGSRSASRQTRNDEQSGDGSRHSGSRHHEASSRADSSGHSQVG-QGQSEGPRT 2559
D+SH S S+S SR+ + D +S + S S D + SQ G Q S +
Sbjct: 386 EDSSHTLSHSKSESREEQADSESSESLNFS---EESPESPEDENSSSQEGLQSHSSSAES 442
Query: 2560 SRNWGSSFSQDSDSQGHSEDSERWSGSASRN 2590
S DSDSQ S E + + S++
Sbjct: 443 QSEESHSEEDDSDSQDSSRSKEDSNSTESKS 473
Score = 71.2 bits (173), Expect = 2e-11
Identities = 107/520 (20%), Positives = 171/520 (32%), Gaps = 73/520 (14%)
Query: 333 SRHPRSHDEDRAS-HGHSADSSRQSGTRHAETSSRGQTASSHEQARSSPGERHGSGHQQS 391
+R+ + ED GH A + + + SS G SS EQA P + S
Sbjct: 20 TRYQNNESEDSEEWKGHLAQAP--TPPLESSESSEGSKVSSEEQANEDPSDSTQSEEGLG 77
Query: 392 ADSSRHSATGRGQASSAVSDRGHRGSSGSQASDSEGHSENSDTQSVSGHGKAGLRQQSHQ 451
+D ++ G S + G G D E S DT G +G + Q
Sbjct: 78 SDDHQYIYRLAGGFSRST------GKGGDDKDDDEDDS-GDDT---FGDDDSGPGPKDRQ 127
Query: 452 ESTRGRSGERSGRSGSSLYQVSTHEQPDSAHGRTGTSTGGRQGSHHEQARDSSRHSASQE 511
E R G S Q S P + A+D++ S +
Sbjct: 128 EGGNSRLG--SDEDSDDTIQASEESAPQG----------------QDSAQDTTSESRELD 169
Query: 512 GQDTIRGHPGSSRGGRQGSHHEQSVNRSGHSGSHHSHTTSQGRSDASHGQSGSRSASRQT 571
+D + P ++ E V S H + S + R
Sbjct: 170 NEDRVDSKPEGGDSTQESESEEHWVGGGSDGESSHGDGSELDDEGMQSDDPESIRSERGN 229
Query: 572 RNEEQSGDGTRHSGSRHHEASSQADSS------------RHSQVGQGQSSGPRTSRNQGS 619
+G ++ SG +A++Q R S++ + N
Sbjct: 230 SRMNSAGMKSKESGENSEQANTQDSGGSQLLEHPSRKIFRKSRISEEDDRSELDDNNTME 289
Query: 620 SVSQDSDSQGHSEDSERWSGSASRNHHGSAQEQSRDGSRHPRSHHEDRAGHGHSADSSRK 679
V DS +S D+ R+ G +QE S++ S + D G S++SS++
Sbjct: 290 EVKSDSTENSNSRDTGL--SQPRRDSKGDSQEDSKENLSQEESQNVD----GPSSESSQE 343
Query: 680 SGTRHTQNSSSGQAASSHEQARSSAGERHGSRHQLQSADSSRHSGTGHGQASSAVRDSGH 739
+ +NSS Q E S G+ + D + + S+ DS H
Sbjct: 344 ANLSSQENSSESQ----EEVVSESRGD---------NPDPTTSYVEDQEDSDSSEEDSSH 390
Query: 740 RGSSGSQATDSEGHSEDSDTQSVSGHGQAGHHQQSHQESARDRSGERSRRSGSFLYQVST 799
T S SE + Q+ S ++ + + ES D + S + G + S
Sbjct: 391 --------TLSHSKSESREEQADSESSESLNFSEESPESPEDENS--SSQEGLQSHSSSA 440
Query: 800 HKQSESSHGWTGPSTGVRQGSHHEQARD-NSRHSASQDGQ 838
QSE SH S E + S+ S+ +DGQ
Sbjct: 441 ESQSEESHSEEDDSDSQDSSRSKEDSNSTESKSSSEEDGQ 480
Score = 71.2 bits (173), Expect = 2e-11
Identities = 91/462 (19%), Positives = 163/462 (35%), Gaps = 25/462 (5%)
Query: 3494 QSGDGSRHSWSHHHEASTQADSSRHSQSGQGQSAGPRTSRNQGSSVSQDSDSQGHSEDSE 3553
+S +GS+ S +A+ S S+ G G R G +D E
Sbjct: 49 ESSEGSKVS--SEEQANEDPSDSTQSEEGLGSDDHQYIYRLAGGFSRSTGKGGDDKDDDE 106
Query: 3554 RWSGSAS--RNHRGSAQEQSRDGSRHPTSHHEDRAGHGHSAESSRQSGTHHAENSSGGQA 3611
SG + + G + ++G ED ++E S G A++++
Sbjct: 107 DDSGDDTFGDDDSGPGPKDRQEGGNSRLGSDEDSDDTIQASEESAPQGQDSAQDTTSESR 166
Query: 3612 ASSHEQARSSAGERHGSHHQQSADSSRHSGIGHGQASSAVRDSGHRGSSGSQASDSEGHS 3671
+E S E G Q ++S H G S+ D G Q+ D E
Sbjct: 167 ELDNEDRVDSKPE--GGDSTQESESEEHWVGGGSDGESSHGDGSELDDEGMQSDDPESIR 224
Query: 3672 EDSDTQSVSAHGQAGPHQQSHQESTRGRSAGRSGRSGSFLYQVSTHEQSESAHGRAGPST 3731
+ +++ G + E + +G S ++ + R S
Sbjct: 225 SERGNSRMNSAGMKSKESGENSEQANTQDSGGSQLLEHPSRKIFRKSRISEEDDR---SE 281
Query: 3732 GGRQGSRHEQARDSSRHSASQEGQDTIRGHPGSRRGGRQGSYHEQSVDRSGHSGSHHSHT 3791
+ E DS+ +S S+ DT P RR + S + + S +
Sbjct: 282 LDDNNTMEEVKSDSTENSNSR---DTGLSQP--RRDSKGDSQEDSKENLSQEESQNVDGP 336
Query: 3792 TSQGRSDASHGQSGSRSASRETRNEEQSGDGSRHSGS----RHHEASTQADSSRHSQSGQ 3847
+S+ +A+ + S S+E E GD + S + S++ DSS +
Sbjct: 337 SSESSQEANLSSQENSSESQEEVVSESRGDNPDPTTSYVEDQEDSDSSEEDSSHTLSHSK 396
Query: 3848 GESAGSRRSRRQGSSVSQDSDSEAYPEDSERRSESASRNHHGSSREQSRDG-SRHPGSSH 3906
ES + S++ +S PED S+ ++H S+ QS + S S
Sbjct: 397 SESREEQADSESSESLNFSEESPESPEDENSSSQEGLQSHSSSAESQSEESHSEEDDSDS 456
Query: 3907 RDTASHVQSSPVQSDSSTAKEHGHFSSLSQDS------AYHS 3942
+D++ + S S+++E G ++ +S AYH+
Sbjct: 457 QDSSRSKEDSNSTESKSSSEEDGQLKNIEIESRKLTVDAYHN 498
Score = 70.1 bits (170), Expect = 4e-11
Identities = 93/468 (19%), Positives = 159/468 (33%), Gaps = 42/468 (8%)
Query: 2968 EQARSSAGERHGSHHQQSADSS----RHSGIGHGQASSAVRDSGHRGYSGSQASDNEGHS 3023
E + SS G + S Q + D S G+G R +G S + D++
Sbjct: 46 ESSESSEGSKVSSEEQANEDPSDSTQSEEGLGSDDHQYIYRLAGGFSRSTGKGGDDKDDD 105
Query: 3024 EDSDTQSVSAHGQAGSHQQSHQESARGRSGETSGHSGSFLYQVSTHEQSESSHGWTGPST 3083
ED +G + QE R G T + SE S
Sbjct: 106 EDDSGDDTFGDDDSGPGPKDRQEGGNSRLGSDEDSD-------DTIQASEES-------- 150
Query: 3084 RGRQGSRHEQAQDSSRHSASQYGQDTIRGHPGSSRGGRQGYHHEHSVDSSGHSGSHHSHT 3143
QG + AQD++ S +D + P ++ EH V S H
Sbjct: 151 -APQGQ--DSAQDTTSESRELDNEDRVDSKPEGGDSTQESESEEHWVGGGSDGESSHGDG 207
Query: 3144 TSQGRSDASRGQSGSRSASRTTRNEEQSGDSSRHSVSRHHEASTHADISRHSQAVQGQSE 3203
+ S + R +G S+ S +A+T S SQ ++ S
Sbjct: 208 SELDDEGMQSDDPESIRSERGNSRMNSAGMKSKESGENSEQANTQD--SGGSQLLEHPSR 265
Query: 3204 GSRRSRRQGSSVSQDSDSEGHSEDSERWSGSASRNHRGSVQEQSRHGSRHPRSHHEDRAG 3263
R R + + ++ + + + + N R + Q R S+
Sbjct: 266 KIFRKSRISEEDDRSELDDNNTMEEVKSDSTENSNSRDTGLSQPRRDSK----------- 314
Query: 3264 HGHSADRSRQSGTRHAETSSGGQAASSHEQARSSPGERHGSRHQQSADSSRHSGIPRGQA 3323
G S + S+++ ++ + G ++ S ++A S E ++ SR G
Sbjct: 315 -GDSQEDSKENLSQEESQNVDGPSSESSQEANLSSQENSSESQEEVVSESR--GDNPDPT 371
Query: 3324 SSAVRDSRHWGSSGSQASDSEGHS--EESDTQSVSGHGQAGPHQQSHQESARDRSGGRSG 3381
+S V D SS +S + HS E + Q+ S ++ + ES D + S
Sbjct: 372 TSYVEDQEDSDSSEEDSSHTLSHSKSESREEQADSESSESLNFSEESPESPEDENS--SS 429
Query: 3382 RSGSFLYQVSTHEQSESAHGRTRTSTGRRQGSHHEQARDSSRHSASQE 3429
+ G + S QSE +H S + E + + S+S+E
Sbjct: 430 QEGLQSHSSSAESQSEESHSEEDDSDSQDSSRSKEDSNSTESKSSSEE 477
Score = 69.7 bits (169), Expect = 6e-11
Identities = 111/465 (23%), Positives = 174/465 (37%), Gaps = 55/465 (11%)
Query: 3549 SEDSERWSG-------------SASRNHRGSAQEQSRDGSRHPTSHHEDRAGHGHSAESS 3595
SEDSE W G +S + S++EQ+ + T E H
Sbjct: 27 SEDSEEWKGHLAQAPTPPLESSESSEGSKVSSEEQANEDPSDSTQSEEGLGSDDHQY-IY 85
Query: 3596 RQSGTHHAENSSGGQAASSHEQARSSAGERHGSHHQQSADSSRHSG----IGHGQASS-- 3649
R +G GG E S + G R G +G + S
Sbjct: 86 RLAGGFSRSTGKGGDDKDDDED--DSGDDTFGDDDSGPGPKDRQEGGNSRLGSDEDSDDT 143
Query: 3650 --AVRDSGHRGSSGSQASDSEGHSEDSDTQ--SVSAHGQAGPHQQSHQESTRGRSAGRSG 3705
A +S +G +Q + SE D++ + S G + +S + G S G S
Sbjct: 144 IQASEESAPQGQDSAQDTTSESRELDNEDRVDSKPEGGDSTQESESEEHWVGGGSDGESS 203
Query: 3706 RS-GSFLYQVSTH-EQSESAHGRAGPSTGGRQGSRHEQARDSSRHSASQE-GQDTIRGHP 3762
GS L + ES G S G + +++ ++S + +Q+ G + HP
Sbjct: 204 HGDGSELDDEGMQSDDPESIRSERGNSRMNSAGMKSKESGENSEQANTQDSGGSQLLEHP 263
Query: 3763 GSRRGGRQGSYHEQSVDRSG-----------HSGSHHSHTTSQGRSDASHGQSG-SRSAS 3810
SR+ R+ E+ DRS + +S++ G S G S+ S
Sbjct: 264 -SRKIFRKSRISEED-DRSELDDNNTMEEVKSDSTENSNSRDTGLSQPRRDSKGDSQEDS 321
Query: 3811 RETRNEEQSG--DGSRHSGSRHHEASTQADSSRHSQSGQGESAGSRRSRRQGSSVSQDSD 3868
+E ++E+S DG S+ S+Q +SS + ES G S V D
Sbjct: 322 KENLSQEESQNVDGPSSESSQEANLSSQENSSESQEEVVSESRGDNPDPTT-SYVEDQED 380
Query: 3869 SEAYPEDSER---RSESASRNHHGSSR-EQSRDGSRHPGSSHRDTASHVQSSPVQSDSST 3924
S++ EDS S+S SR S +S + S S D S Q +QS SS+
Sbjct: 381 SDSSEEDSSHTLSHSKSESREEQADSESSESLNFSEESPESPEDENSSSQEG-LQSHSSS 439
Query: 3925 AKEHGHFSSLSQDSAYHSGIQSRGSPHSSSSYHYQSEGTERQKGQ 3969
A+ S +D + S SR S+S+ +S+ + + GQ
Sbjct: 440 AESQSEESHSEEDDS-DSQDSSRSKEDSNST---ESKSSSEEDGQ 480
Score = 68.9 bits (167), Expect = 9e-11
Identities = 100/483 (20%), Positives = 177/483 (36%), Gaps = 35/483 (7%)
Query: 1683 SRHQQSADSSTDSGTGRRQDSSVVGDSGNRGSSGSQASDSEGHSEESDTQSVSAHGQAGP 1742
+R+Q + ++ G + + S GS+ S E +E+ S S + G
Sbjct: 20 TRYQNNESEDSEEWKGHLAQAPTPPLESSESSEGSKVSSEEQANED---PSDSTQSEEGL 76
Query: 1743 HQQSHQESTRGQSG-ERSGRSGSFLYQVSTHEQSESAHGRTGPSTGGRQRSRHEQARDSS 1801
HQ R G RS G + + G G + R Q +S
Sbjct: 77 GSDDHQYIYRLAGGFSRSTGKGGDDKDDDEDDSGDDTFGDDDSGPGPKDR----QEGGNS 132
Query: 1802 RHSASQEGQDTIRGHPGSSRGGRQGSHYEQSVDSSGHSGSHHSHTTSQERSDVSRGQSGS 1861
R + ++ DTI+ S+ G+ DS+ + S +++R D S+ + G
Sbjct: 133 RLGSDEDSDDTIQASEESAPQGQ---------DSAQDTTSESRELDNEDRVD-SKPEGGD 182
Query: 1862 RSVSRQTRNEKQSGDGSRHSGSRHHEASSRADSSRHSQVGQGQSSGPRTSR-NQGSSVSQ 1920
++++ +E+ G S H + S D S + S SR N S+
Sbjct: 183 S--TQESESEEHWVGGGSDGESSHGDGSELDDEGMQSDDPESIRSERGNSRMNSAGMKSK 240
Query: 1921 DSDSQGHSEDSERWSGSASRNHLG-SAWEQSRDGSRHPGSHHED-RAGHGHSADSSRQSG 1978
+S +++ GS H + +SR S +D +DS+ S
Sbjct: 241 ESGENSEQANTQDSGGSQLLEHPSRKIFRKSRISEEDDRSELDDNNTMEEVKSDSTENSN 300
Query: 1979 TRHTESSS--RGQAASSHEQARSSAGERHGSHHQLQSADSSRHSGIGHGQASSAVRDSGH 2036
+R T S R S E ++ + + + S++SS+ + + + SS ++
Sbjct: 301 SRDTGLSQPRRDSKGDSQEDSKENLSQEESQNVDGPSSESSQEANLSSQENSSESQEEVV 360
Query: 2037 RGYSGSQASDSEGHSEDSDTQSVSAQGKAGPHQQSHKESARGQSGESSGRSGSFLYQVST 2096
G + + ED + S + + S ES Q+ S S +F +
Sbjct: 361 SESRGDNPDPTTSYVEDQEDSDSSEEDSSHTLSHSKSESREEQADSESSESLNF-----S 415
Query: 2097 HEQSESTHGQSAPSTGGRQGSHYDQAQDSSRHSASQE----GQDTIRGHPGPSRGGRQGS 2152
E ES +++ S G Q SH A+ S S S+E QD+ R + + S
Sbjct: 416 EESPESPEDENSSSQEGLQ-SHSSSAESQSEESHSEEDDSDSQDSSRSKEDSNSTESKSS 474
Query: 2153 HQE 2155
+E
Sbjct: 475 SEE 477
Score = 68.9 bits (167), Expect = 9e-11
Identities = 113/532 (21%), Positives = 191/532 (35%), Gaps = 97/532 (18%)
Query: 800 HKQSESSHGWTG-----PSTGVRQGSHHEQARDNSRHSASQDGQDTIRGHPGSSRRGRQG 854
+ +SE S W G P+ + E ++ +S A++D D+ + G G
Sbjct: 24 NNESEDSEEWKGHLAQAPTPPLESSESSEGSKVSSEEQANEDPSDSTQSEEGL------G 77
Query: 855 SHHEQSVDRSGHSGSHHSHTTSQGRSDASRGQSGSRSASRTTRNEEQSRDGSRHSGSRHH 914
S Q + R S +T +G D + S ++ D G +
Sbjct: 78 SDDHQYIYRLAGG---FSRSTGKGGDDKDDDEDDS--------GDDTFGDDDSGPGPKDR 126
Query: 915 EASSHADISRHSQAGQGQSEGSRTSRRQGSSVSQDSDSEGHSEDSERWSGSASRNHRGSA 974
+ ++ + + + S S QG +QD+ SE D+E S +
Sbjct: 127 QEGGNSRLGSDEDSDD-TIQASEESAPQGQDSAQDTTSESRELDNEDRVDSKPEGGDSTQ 185
Query: 975 QEQSRHGSRHPRSHHEDRAGHGHSADSSRQSGTPHAETSSGGQAASSHEQARSSPGERHG 1034
+ +S E G G +SS G+ E G + E RS ER
Sbjct: 186 ESESE----------EHWVGGGSDGESSHGDGS---ELDDEGMQSDDPESIRS---ERGN 229
Query: 1035 SRHQQSADSSRHSGIPRRQASSAVRDSGHWGSS-----------GSQASDSEGHSEESDT 1083
SR + S+ SG QA++ +DSG GS S+ S+ + SE D
Sbjct: 230 SRMNSAGMKSKESGENSEQANT--QDSG--GSQLLEHPSRKIFRKSRISEEDDRSELDDN 285
Query: 1084 QSVSGHGQDGPHQQSHQESA-----RDWSGGRSGRSGSFIYQVSTHEQSESAHGRTRTST 1138
++ D + +++ RD G S + Q E+S++ G + S+
Sbjct: 286 NTMEEVKSDSTENSNSRDTGLSQPRRDSKGDSQEDSKENLSQ----EESQNVDGPSSESS 341
Query: 1139 GRRQGSHHEQARDSSRHSASQEGQDTIRAHPGSRRGGRQGSHHEQSVDRSGHSGSHHSHT 1198
S E + +S S+ D P + Q + S + S H+ SH
Sbjct: 342 QEANLSSQENSSESQEEVVSESRGDN--PDPTTSYVEDQ-EDSDSSEEDSSHTLSH---- 394
Query: 1199 TSQGRSDASHGQSGSRSASRQTRKDKQSGDGSRHSGSRHHEAASWADSSRHSQVGQEQSS 1258
S+S SR+ + D +S E+ ++++ S S + SS
Sbjct: 395 --------------SKSESREEQADSESS-----------ESLNFSEESPESPEDENSSS 429
Query: 1259 GSRTSRHQGSSVSQDSDSERHSDDSERLSGSASRNHHGSSREQSRDGSRHPG 1310
H S+ SQ +S DDS+ S +SR+ S+ +S+ S G
Sbjct: 430 QEGLQSHSSSAESQSEESHSEEDDSD--SQDSSRSKEDSNSTESKSSSEEDG 479
Score = 68.2 bits (165), Expect = 2e-10
Identities = 103/460 (22%), Positives = 162/460 (35%), Gaps = 49/460 (10%)
Query: 1928 SEDSERWSG----------SASRNHLGSAWEQSRDGSRHPGSHHEDRAGHGHSADSSRQS 1977
SEDSE W G +S + GS + P + G G S D
Sbjct: 27 SEDSEEWKGHLAQAPTPPLESSESSEGSKVSSEEQANEDPSDSTQSEEGLG-SDDHQYIY 85
Query: 1978 GTRHTESSSRGQAASSHEQARSSAGERHGSHHQLQSADSSRHSG----IGHGQASS---- 2029
S S G+ + +G+ R G +G + S
Sbjct: 86 RLAGGFSRSTGKGGDDKDDDEDDSGDDTFGDDDSGPGPKDRQEGGNSRLGSDEDSDDTIQ 145
Query: 2030 AVRDSGHRGYSGSQASDSEGHSEDSDTQSVSAQGKAGPHQQSHKES---ARGQSGESSGR 2086
A +S +G +Q + SE D++ + S Q+S E G GESS
Sbjct: 146 ASEESAPQGQDSAQDTTSESRELDNEDRVDSKPEGGDSTQESESEEHWVGGGSDGESSHG 205
Query: 2087 SGSFL----YQVSTHEQSESTHGQSAPSTGGRQGSHYDQAQDSSRHSASQEGQDTIRGHP 2142
GS L Q E S G S ++ G + + ++S + + G + HP
Sbjct: 206 DGSELDDEGMQSDDPESIRSERGNSRMNSAGMKSK--ESGENSEQANTQDSGGSQLLEHP 263
Query: 2143 GPS--RGGRQGSHQEQS-VD--------RSGHSGSHHSHTT--SQGRSDASRGQSGSRSA 2189
R R ++S +D +S + + +S T SQ R D S+G S S
Sbjct: 264 SRKIFRKSRISEEDDRSELDDNNTMEEVKSDSTENSNSRDTGLSQPRRD-SKGDSQEDSK 322
Query: 2190 SRKTYDKEQSGDGSRHSGSHHHEASSWADSS--RHSLVGQGQSSGPRTSRPRGSSVSQDS 2247
+ ++ Q+ DG S SS +SS + +V + + P P S V
Sbjct: 323 ENLSQEESQNVDGPSSESSQEANLSSQENSSESQEEVVSESRGDNPD---PTTSYVEDQE 379
Query: 2248 DSEGHSEDSERR-SGSASRNHHGSAQEQSRDGSRHPRSHHEDRAGHGHSAESSRQSGTHH 2306
DS+ EDS S S S + A +S + E S++ QS +
Sbjct: 380 DSDSSEEDSSHTLSHSKSESREEQADSESSESLNFSEESPESPEDENSSSQEGLQSHSSS 439
Query: 2307 AEN-SSGGQAASSHEQARSSAGERHGSHHQQSADSSRHSG 2345
AE+ S + ++ S+ + S+ +S SS G
Sbjct: 440 AESQSEESHSEEDDSDSQDSSRSKEDSNSTESKSSSEEDG 479
Score = 67.8 bits (164), Expect = 2e-10
Identities = 110/477 (23%), Positives = 161/477 (33%), Gaps = 68/477 (14%)
Query: 2416 YQVSTHEQSESAHGR----------TGTSTGGRQGSHHKQARDSSRHSTSQE---GQDTI 2462
YQ + E SE G + S+ G + S +QA + ST E G D
Sbjct: 22 YQNNESEDSEEWKGHLAQAPTPPLESSESSEGSKVSSEEQANEDPSDSTQSEEGLGSDD- 80
Query: 2463 HGHPGSSSGGRQGSHYEQLVDRSGHSGSHHSHTTSQGRSDASHGHSGSRSASRQTRNDEQ 2522
H + +GG RS G D + G S + D Q
Sbjct: 81 HQYIYRLAGG---------FSRSTGKGGDDKDDDEDDSGDDTFGDDDSGPGPK----DRQ 127
Query: 2523 SGDGSRHSGSRHHEASSRADSSGHSQVGQGQSEGPRTSRNWGSSFSQDS-----DSQGHS 2577
G SR + + +A Q + SR + DS DS S
Sbjct: 128 EGGNSRLGSDEDSDDTIQASEESAPQGQDSAQDTTSESRELDNEDRVDSKPEGGDSTQES 187
Query: 2578 EDSERWSGSAS--RNHHGSAQEQLRDG--SRHPRSHQEDRAGHG------HSADSSRQSG 2627
E E W G S + HG E +G S P S + +R S +S S
Sbjct: 188 ESEEHWVGGGSDGESSHGDGSELDDEGMQSDDPESIRSERGNSRMNSAGMKSKESGENSE 247
Query: 2628 TRHTQTSSGGQAAS------------SHEQARSSAGERHGSHHQQSADSSRHSGIGHGQA 2675
+TQ S G Q S E RS + + +S DS+ +S
Sbjct: 248 QANTQDSGGSQLLEHPSRKIFRKSRISEEDDRSELDDNNTMEEVKS-DSTENSNSRDTGL 306
Query: 2676 SSAVRDSGHRGYSGSQASDNEGHSEDSDTQSVSAHGQAGSHQQSHQESARGRSGETSGHS 2735
S RDS +G S + +N E + S+ ++ S + S+ + S
Sbjct: 307 SQPRRDS--KGDSQEDSKENLSQEESQNVDGPSSESSQEANLSSQENSSESQEEVVSESR 364
Query: 2736 GS----FLYQVSTHEQSESSHGWTGPS-TRGRQGSRHEQAQDSSRHSA--SQDGQDTIRG 2788
G V E S+SS + + + + SR EQA S S S++ ++
Sbjct: 365 GDNPDPTTSYVEDQEDSDSSEEDSSHTLSHSKSESREEQADSESSESLNFSEESPESPED 424
Query: 2789 HPGSSRGGRQGYHHEHSVDSSGHSGSHHSHTTSQGRSDASRGQSGSRSASRTTRNEE 2845
SS+ G Q HS + S HS D+SR + S S + +EE
Sbjct: 425 ENSSSQEGLQS----HSSSAESQSEESHSEEDDSDSQDSSRSKEDSNSTESKSSSEE 477
Score = 67.4 bits (163), Expect = 3e-10
Identities = 93/445 (20%), Positives = 162/445 (36%), Gaps = 39/445 (8%)
Query: 556 DASHGQSGSRSASRQTRNEEQSGDGTRHSGSRHHEASSQADSSRHSQVGQGQSSGPRTSR 615
++S GS+ +S + NE+ S G S H + + R++
Sbjct: 46 ESSESSEGSKVSSEEQANEDPSDSTQSEEG---------LGSDDHQYIYRLAGGFSRSTG 96
Query: 616 NQGSSVSQDSDSQGHSE--DSERWSGSASRNHHGSAQEQSRDGSRHPRSHHEDRAGHGHS 673
G D D G D + G R G+++ S + S E+ A G
Sbjct: 97 KGGDDKDDDEDDSGDDTFGDDDSGPGPKDRQEGGNSRLGSDEDSDDTIQASEESAPQGQD 156
Query: 674 ADSSRKSGTRHTQNSSSGQAA-SSHEQARSSAGERH----GSRHQLQSADSSRHSGTG-- 726
+ S +R N + + + S E H GS + D S G
Sbjct: 157 SAQDTTSESRELDNEDRVDSKPEGGDSTQESESEEHWVGGGSDGESSHGDGSELDDEGMQ 216
Query: 727 --HGQASSAVRDSGHRGSSGSQATDSEGHSEDSDTQSVSGHGQAGHHQQSHQESARDRSG 784
++ + R + S+G ++ +S +SE ++TQ SG Q H S + + R
Sbjct: 217 SDDPESIRSERGNSRMNSAGMKSKESGENSEQANTQD-SGGSQLLEHP-SRKIFRKSRIS 274
Query: 785 ERSRRSGSFLYQVSTHKQSESSHGWTGPSTGVRQGSHHEQ--ARDNSRHSASQDGQDTIR 842
E RS +S+S+ TG+ Q + ++++S+ + SQ+ +
Sbjct: 275 EEDDRSELDDNNTMEEVKSDSTENSNSRDTGLSQPRRDSKGDSQEDSKENLSQEESQNVD 334
Query: 843 GHPGSSRRGRQGSHHEQSVDR-----SGHSGSHHSHTTS----QGRSDASRGQSGSRSAS 893
G S + S E S + S G + TTS Q SD+S S +
Sbjct: 335 GPSSESSQEANLSSQENSSESQEEVVSESRGDNPDPTTSYVEDQEDSDSSEEDSSHTLSH 394
Query: 894 RTTRNEEQSRDGSRHSGSRHHEASSHADISRHSQAGQGQSEGSRTSRRQGSSVSQDSDSE 953
+ + E+ D E S + +S + +G S ++ Q S++S SE
Sbjct: 395 SKSESREEQADSESSESLNFSEESPESPEDENSSSQEGLQSHSSSAESQ----SEESHSE 450
Query: 954 GHSEDSERWSGSASRNHRGSAQEQS 978
+DS+ S S+ S + +S
Sbjct: 451 --EDDSDSQDSSRSKEDSNSTESKS 473
Score = 66.2 bits (160), Expect = 6e-10
Identities = 91/438 (20%), Positives = 153/438 (34%), Gaps = 30/438 (6%)
Query: 2320 EQARSSAGERHGSHHQQSADSS----RHSGIGHGQASSAVRDSGHRGSSGSQASDSEGHS 2375
E + SS G + S Q + D S G+G R +G S + D +
Sbjct: 46 ESSESSEGSKVSSEEQANEDPSDSTQSEEGLGSDDHQYIYRLAGGFSRSTGKGGDDKDDD 105
Query: 2376 EDSDTQSVSAHGQAGPHQQSHQESTRGRSAGRSGRSGSFLYQVSTHEQSESAHGRTGTST 2435
ED +GP + QE G S S Q S + T++
Sbjct: 106 EDDSGDDTFGDDDSGPGPKDRQEG--GNSRLGSDEDSDDTIQASEESAPQGQDSAQDTTS 163
Query: 2436 GGRQGSHHKQARDSSRHSTS-QEGQDTIHGHPGSSSGGRQGSHYEQLVDRSGHSGSHHSH 2494
R+ + + S QE + H G S G +L D S S
Sbjct: 164 ESRELDNEDRVDSKPEGGDSTQESESEEHWVGGGSDGESSHGDGSELDDEGMQSDDPESI 223
Query: 2495 TTSQGRSDA-SHGHSGSRSASRQTRNDEQSGDGSR---------HSGSRHHEASSRADSS 2544
+ +G S S G S + + Q GS+ SR E R++
Sbjct: 224 RSERGNSRMNSAGMKSKESGENSEQANTQDSGGSQLLEHPSRKIFRKSRISEEDDRSELD 283
Query: 2545 GHSQVGQGQSEGPRTSRNWGSSFSQDS-DSQGHSEDS--ERWSGSASRNHHG----SAQE 2597
++ + + +S+ S + + SQ DS+G S++ E S S+N G S+QE
Sbjct: 284 DNNTMEEVKSDSTENSNSRDTGLSQPRRDSKGDSQEDSKENLSQEESQNVDGPSSESSQE 343
Query: 2598 QLRDGSRHPRSHQED--RAGHGHSADSSRQSGTRHTQTSSGGQAASSHEQARSSAGERHG 2655
+ QE+ G + D + S + S + SSH + S + R
Sbjct: 344 ANLSSQENSSESQEEVVSESRGDNPDPTT-SYVEDQEDSDSSEEDSSHTLSHSKSESREE 402
Query: 2656 SHHQQSADS---SRHSGIGHGQASSAVRDSGHRGYSGSQASDNEGHSEDSDTQSVSAHGQ 2712
+S++S S S +S+ ++ S +++ E HSE+ D+ S +
Sbjct: 403 QADSESSESLNFSEESPESPEDENSSSQEGLQSHSSSAESQSEESHSEEDDSDSQDSSRS 462
Query: 2713 AGSHQQSHQESARGRSGE 2730
+ +S+ G+
Sbjct: 463 KEDSNSTESKSSSEEDGQ 480
Score = 60.1 bits (144), Expect = 4e-08
Identities = 85/392 (21%), Positives = 137/392 (34%), Gaps = 44/392 (11%)
Query: 3616 EQARSSAGERHGSHHQQSADSS----RHSGIGHGQASSAVRDSGHRGSSGSQASDSEGHS 3671
E + SS G + S Q + D S G+G R +G S + D +
Sbjct: 46 ESSESSEGSKVSSEEQANEDPSDSTQSEEGLGSDDHQYIYRLAGGFSRSTGKGGDDKDDD 105
Query: 3672 EDSDTQSVSAHGQAGPHQQSHQESTRGRSAGRSGRSGSFLYQVSTHEQSESAHGRAGPST 3731
ED +GP + QE G + R GS T + SE +
Sbjct: 106 EDDSGDDTFGDDDSGPGPKDRQE-------GGNSRLGSDEDSDDTIQASEES-------- 150
Query: 3732 GGRQGSRHEQARDSSRHSASQEGQDTIRGHPGSRRGGRQGSYHEQSVDRSGHSGSHHSHT 3791
QG + A+D++ S + +D + P ++ E V G S SH
Sbjct: 151 -APQG--QDSAQDTTSESRELDNEDRVDSKPEGGDSTQESESEEHWV--GGGSDGESSHG 205
Query: 3792 TSQGRSDASHGQSGSRSASRETRNEEQSGDG--SRHSGSRHHEASTQADSSRHSQSGQGE 3849
D S E N + G S+ SG +A+TQ S Q
Sbjct: 206 DGSELDDEGMQSDDPESIRSERGNSRMNSAGMKSKESGENSEQANTQ-----DSGGSQLL 260
Query: 3850 SAGSRRSRRQGSSVSQDSDSEAYPEDSERRSESASRNHHGSSREQS-----RDGSRHPGS 3904
SR+ R+ S +S++ D +++ + + +SR+ RD
Sbjct: 261 EHPSRKIFRK-SRISEEDDRSELDDNNTMEEVKSDSTENSNSRDTGLSQPRRDSKGDSQE 319
Query: 3905 SHRDTASHVQSSPVQSDSSTAKEHGHFSSLSQDSAYHSGI--QSRG-SPHSSSSYHYQSE 3961
++ S +S V SS + + + SS S + +SRG +P ++SY E
Sbjct: 320 DSKENLSQEESQNVDGPSSESSQEANLSSQENSSESQEEVVSESRGDNPDPTTSYVEDQE 379
Query: 3962 GTERQKGQSGLVWRHGSYGS----ADYDYGES 3989
++ + S H S AD + ES
Sbjct: 380 DSDSSEEDSSHTLSHSKSESREEQADSESSES 411
Score = 57.8 bits (138), Expect = 2e-07
Identities = 93/449 (20%), Positives = 165/449 (36%), Gaps = 43/449 (9%)
Query: 108 DKHEDNKQEENKENRKRPSSLERRNNRKGNKGRSKSPRETGGKRHESSSEKKERKGYSPT 167
+ E +K ++ + PS + G+ R GG + ++
Sbjct: 49 ESSEGSKVSSEEQANEDPSDSTQSEEGLGSDDHQYIYRLAGGFSRSTGKGGDDKDDDEDD 108
Query: 168 HREEEYGKNHHNSSKKEKNKTENTRLGDNRKRLSERLEEKEDNEEGVYDYENTGRMTQKW 227
++ +G + K++ + N+RLG + ED+++ + E + Q
Sbjct: 109 SGDDTFGDDDSGPGPKDRQEGGNSRLGSD-----------EDSDDTIQASEESAPQGQ-- 155
Query: 228 IQSGHIATYYTIQDEAYDTTDSLLEENKIYERSRS--------SDGKSS----SQVNRSR 275
S T + + + D DS E + S S SDG+SS S+++
Sbjct: 156 -DSAQDTTSESRELDNEDRVDSKPEGGDSTQESESEEHWVGGGSDGESSHGDGSELDDEG 214
Query: 276 HENTSQVPLQESRTRKRRGSRVSQDRDSEGHSEDSE-RHSGSASRNHHGSAWEQSRDGSR 334
++ ++ R R S + ++S +SE + + SG + H SR R
Sbjct: 215 MQSDDPESIRSERGNSRMNSAGMKSKESGENSEQANTQDSGGSQLLEH-----PSRKIFR 269
Query: 335 HPRSHDEDRASHGHSADSSRQSGTRHAETSSRGQTASSHEQARSSPGERHGSGHQQSADS 394
R +ED S ++ + + E S+ T S + S + S S +
Sbjct: 270 KSRISEEDDRSELDDNNTMEEVKSDSTENSNSRDTGLSQPRRDSKGDSQEDSKENLSQEE 329
Query: 395 SRHSATGRGQASSAVSDRGHRGSSGSQ---ASDSEGHSENSDTQSVSGHGKAGLRQQ--S 449
S++ ++S + SS SQ S+S G + + T V + ++ S
Sbjct: 330 SQNVDGPSSESSQEANLSSQENSSESQEEVVSESRGDNPDPTTSYVEDQEDSDSSEEDSS 389
Query: 450 HQES-TRGRSGERSGRSGSSLYQVSTHEQPDSAHGRTGTSTGGRQGSHHEQARDSSRHSA 508
H S ++ S E S SS + E P+S +S G Q SH A S S
Sbjct: 390 HTLSHSKSESREEQADSESSESLNFSEESPESPEDENSSSQEGLQ-SHSSSAESQSEESH 448
Query: 509 SQE----GQDTIRGHPGSSRGGRQGSHHE 533
S+E QD+ R S+ + S E
Sbjct: 449 SEEDDSDSQDSSRSKEDSNSTESKSSSEE 477
Score = 52.4 bits (124), Expect = 9e-06
Identities = 87/424 (20%), Positives = 154/424 (36%), Gaps = 66/424 (15%)
Query: 78 VFKLAQAYYESTRKENLPISGHKHRKHSHHDKHEDNKQEENKENRKRPSSLERRNNRKGN 137
+++LA + ST K D +D+ + ++ P +R+
Sbjct: 84 IYRLAGGFSRSTGKGG----------DDKDDDEDDSGDDTFGDDDSGPGPKDRQEGGNSR 133
Query: 138 KGRSKSPRETGGKRHESS-----------SEKKERKGYSPTHREEEYGKNHHNSSKKEK- 185
G + +T ES+ SE +E + E G + S +E
Sbjct: 134 LGSDEDSDDTIQASEESAPQGQDSAQDTTSESRELDNEDRVDSKPEGGDSTQESESEEHW 193
Query: 186 ---NKTENTRLGDNRKRLSERLEEKEDNEEGVYDYENTGRMTQKWIQSGHIATYYTIQDE 242
+ GD + E ++ D+ E + RM ++S E
Sbjct: 194 VGGGSDGESSHGDGSELDDEGMQS--DDPESIRSERGNSRMNSAGMKSKESGE----NSE 247
Query: 243 AYDTTDS----LLEE--NKIYERSRSSDGKSSSQVNRSRHENTSQVPLQESRTRKRRGSR 296
+T DS LLE KI+ +SR S+ S+++ + +V + R +
Sbjct: 248 QANTQDSGGSQLLEHPSRKIFRKSRISEEDDRSELDDNN--TMEEVKSDSTENSNSRDTG 305
Query: 297 VSQDR-DSEGHSEDSERH--SGSASRNHHGSAWEQSRDGSRHPRSHDEDRA------SHG 347
+SQ R DS+G S++ + S S+N G + E S++ + + + + S G
Sbjct: 306 LSQPRRDSKGDSQEDSKENLSQEESQNVDGPSSESSQEANLSSQENSSESQEEVVSESRG 365
Query: 348 HSADSSRQSGTRHAETSSRGQTASSHEQARSSPGERHGSGHQQSADS---SRHSATGRGQ 404
+ D + S E S + SSH + S R +S++S S S
Sbjct: 366 DNPDPTT-SYVEDQEDSDSSEEDSSHTLSHSKSESREEQADSESSESLNFSEESPESPED 424
Query: 405 ASSAVSDRGHRGSSGSQASDSEGHSENSDTQSVSGHGKAGLRQQSHQESTRGRSGERSGR 464
+S+ + SS +++ E HSE D+ S Q+S+R + S
Sbjct: 425 ENSSSQEGLQSHSSSAESQSEESHSEEDDSDS--------------QDSSRSKEDSNSTE 470
Query: 465 SGSS 468
S SS
Sbjct: 471 SKSS 474
Score = 50.1 bits (118), Expect = 5e-05
Identities = 63/266 (23%), Positives = 104/266 (39%), Gaps = 27/266 (10%)
Query: 156 SEKKERKGYSPTHREEEYGKNHHNSSKKEKNKTENTRLGDNRKRLSERLEEKEDNEEGVY 215
SE+ + S + +E G+N ++ ++ ++ + R+ E++D E
Sbjct: 225 SERGNSRMNSAGMKSKESGENSEQANTQDSGGSQLLEHPSRKIFRKSRISEEDDRSE--L 282
Query: 216 DYENTGRMTQKWIQSGHIATYYTIQDEAYDTTDSLLE---ENKIYERSRSSDG---KSSS 269
D NT + + + D+ E EN E S++ DG +SS
Sbjct: 283 DDNNTMEEVKSDSTENSNSRDTGLSQPRRDSKGDSQEDSKENLSQEESQNVDGPSSESSQ 342
Query: 270 QVNRSRHENTSQVPLQESRTRKRRG-------SRVSQDRDSEGHSEDSER---HSGSASR 319
+ N S EN+S+ QE + RG S V DS+ EDS HS S SR
Sbjct: 343 EANLSSQENSSES--QEEVVSESRGDNPDPTTSYVEDQEDSDSSEEDSSHTLSHSKSESR 400
Query: 320 NHHGSAWEQSRDGSRHPRSHDEDRASHGHSADSSRQSGTRHAETSSRGQTASSH-EQARS 378
EQ+ S + E+ +SS Q G + +S+ Q+ SH E+ S
Sbjct: 401 E------EQADSESSESLNFSEESPESPEDENSSSQEGLQSHSSSAESQSEESHSEEDDS 454
Query: 379 SPGERHGSGHQQSADSSRHSATGRGQ 404
+ S ++ S+ S+ GQ
Sbjct: 455 DSQDSSRSKEDSNSTESKSSSEEDGQ 480
>gi|161016767 mucin 21 [Homo sapiens]
Length = 566
Score = 90.5 bits (223), Expect = 3e-17
Identities = 119/506 (23%), Positives = 202/506 (39%), Gaps = 68/506 (13%)
Query: 2559 TSRNWGSS-FSQDSDSQGHSEDSERWSGSASRNHHGSAQEQLRDGSRHPRSHQEDRAGHG 2617
TS N GSS S + + +S S SG ++ GS+ + + S + H
Sbjct: 29 TSANTGSSVISSGASTATNSGSSVTSSGVSTATISGSSV------TSNGVSIVTNSEFHT 82
Query: 2618 HSADSSRQSGTRHTQTSSGGQAASSHEQARSSAGERHGSHHQQSADSSRHSGIGHGQASS 2677
S+ S + + + SSG A++ E + +S+G ++ + S SS AS+
Sbjct: 83 TSSGISTATNSEFSTVSSGISIATNSESSTTSSGASTATNSESSTPSSG--------AST 134
Query: 2678 AVRDSGHRGYSGSQASDNEGHSEDSDTQSVSAHGQAGSHQQSHQESARGRSGETSGHSGS 2737
A SG+ + N SD+ + S+ ++ +S S+ G S T+ S +
Sbjct: 135 ATNSDSSTTSSGASTATN------SDSSTTSSEASTATNSESSTTSS-GASTATNSESST 187
Query: 2738 FLYQVSTHEQSESSHGWTGPSTRGRQGSRHEQAQDSSRHSASQDGQDTIRGHPGSSRGGR 2797
+ ST SESS +G ST SR +++ G T +S G
Sbjct: 188 VSSRASTATNSESSTTSSGASTA---------TNSESRTTSNGAGTATNSESSTTSSGAS 238
Query: 2798 QGYHHEHSVDSSGHSGSHHSH--TTSQGRSDASRGQSGSRSAS-RTTRNEEQSGDGSRHS 2854
+ E S SSG + +S TTS G A+ +S + S+ T N E S S +
Sbjct: 239 TATNSESSTPSSGAGTATNSESSTTSSGAGTATNSESSTVSSGISTVTNSESSTPSSGAN 298
Query: 2855 GSRHHEASTH---ADISRHSQAVQGQSEGSRRSRRQGSSVSQDSDSEGHSEDSERWSGSA 2911
+ + E+ST A+ + +S + S S + + S+ S + + +SE S SG++
Sbjct: 299 TATNSESSTTSSGANTATNSDSSTTSSGASTATNSESSTTSSGASTATNSESSTTSSGAS 358
Query: 2912 SRNHHGSAQEQLRDGSRHPRSHQEDRAGHGHSADSSRQSGTRHTQTSSGGQAASSHEQAR 2971
+ + GS+ S+ +S + + + SSG A++ E +
Sbjct: 359 TATNSGSSTT---------------------SSGTSTATNSESSTVSSGASTATTSESST 397
Query: 2972 SSAGERHGSHHQQSADSSRHSGIGHGQASSAVRDSGHRGYSGSQASDNEGHSEDSDTQSV 3031
+S+G ++ + S SS AS+A SG+ + N G S S
Sbjct: 398 TSSGASTATNSESSTVSSG--------ASTATNSESSTTSSGANTATNSGSSVTSAGSGT 449
Query: 3032 SAHGQAGSHQQSHQESARGRSGETSG 3057
+A G H SH S + G
Sbjct: 450 AA--LTGMHTTSHSASTAVSEAKPGG 473
Score = 85.1 bits (209), Expect = 1e-15
Identities = 112/469 (23%), Positives = 194/469 (41%), Gaps = 47/469 (10%)
Query: 2294 HSAESSRQSGTHHAENSSGGQAASSHEQARSSAGERHGSHHQQSADSSRHSGIGHGQ--- 2350
+S E+S + T + SSG A++ + +S+G + S S+ S + + +
Sbjct: 23 NSNETSTSANTGSSVISSGASTATNSGSSVTSSGVSTATISGSSVTSNGVSIVTNSEFHT 82
Query: 2351 ----ASSAVRDSGHRGSSG-SQASDSEGHSEDSD----TQSVSAHGQAGPHQQSHQESTR 2401
S+A SSG S A++SE + S T S S+ +G ++ +S+
Sbjct: 83 TSSGISTATNSEFSTVSSGISIATNSESSTTSSGASTATNSESSTPSSGASTATNSDSST 142
Query: 2402 ---GRSAGRSGRSGSFLYQVSTHEQSESAHGRTGTSTGGRQGSHHKQARDSSRHSTSQEG 2458
G S + S + + ST SES+ TS+G ++ + + SSR ST+
Sbjct: 143 TSSGASTATNSDSSTTSSEASTATNSESST----TSSGASTATNSESSTVSSRASTATNS 198
Query: 2459 QDTIHGHPGSSSGGRQGSHYEQLV--DRSGHSGSHHSHTTSQGRSDASHGHSGSRSASRQ 2516
+ + +SSG ++ E + +G + + S TTS G S A++ S + S+
Sbjct: 199 ESST-----TSSGASTATNSESRTTSNGAGTATNSESSTTSSGASTATNSESSTPSSGAG 253
Query: 2517 TRNDEQSGDGSRHSGSRHHEASSRADSSGHSQVGQGQSEGPRTSRNWGSSFSQDSDSQG- 2575
T + +S S +G+ + SS SSG S V +S P + N ++ + S G
Sbjct: 254 TATNSESSTTSSGAGTATNSESSTV-SSGISTVTNSESSTPSSGANTATNSESSTTSSGA 312
Query: 2576 ----HSEDSERWSGSASRNHHGSAQEQLRDGSRHPRSHQEDRAGHGHSADSSRQSGTRHT 2631
+S+ S SG+++ + S+ G+ + + G S ++ S T
Sbjct: 313 NTATNSDSSTTSSGASTATNSESSTTS--SGASTATNSESSTTSSGASTATNSGSST--- 367
Query: 2632 QTSSGGQAASSHEQARSSAGERHGSHHQQSADSSRHSGIGHGQ-------ASSAVRDSGH 2684
TSSG A++ E + S+G + + S SS S + + AS+A
Sbjct: 368 -TSSGTSTATNSESSTVSSGASTATTSESSTTSSGASTATNSESSTVSSGASTATNSESS 426
Query: 2685 RGYSGSQASDNEGHSEDSDTQSVSAHGQAGSHQQSHQESARGRSGETSG 2733
SG+ + N G S S +A G H SH S + G
Sbjct: 427 TTSSGANTATNSGSSVTSAGSGTAA--LTGMHTTSHSASTAVSEAKPGG 473
Score = 84.7 bits (208), Expect = 2e-15
Identities = 119/489 (24%), Positives = 187/489 (38%), Gaps = 59/489 (12%)
Query: 537 NRSGHSGSHHSHTTSQGRSDASHGQSGSRSASRQTRNEEQSGDGTRHSG------SRHHE 590
N + S + S S G S A++ SGS S SG +G S H
Sbjct: 25 NETSTSANTGSSVISSGASTATN--SGSSVTSSGVSTATISGSSVTSNGVSIVTNSEFHT 82
Query: 591 ASSQADSSRHSQVGQGQSSGPRTSRNQGSSVSQDSDSQGHSEDSERWSGSASRNHHGSAQ 650
SS ++ +S+ S + ++ S+ S + + +SE S SG+++ + S+
Sbjct: 83 TSSGISTATNSEFSTVSSGISIATNSESSTTSSGASTATNSESSTPSSGASTATNSDSST 142
Query: 651 EQS--RDGSRHPRSHHEDRAGHGHSADSSR-KSGTRHTQNSSSGQAASSHEQARSSAGER 707
S + S A +++SS SG NS S +S A +S
Sbjct: 143 TSSGASTATNSDSSTTSSEASTATNSESSTTSSGASTATNSESSTVSSRASTATNSESST 202
Query: 708 HGSRHQLQSADSSRHSGTGHGQASSAVRDSGHRGSSGSQATDSEGHSEDSD----TQSVS 763
S + SR + G G A+++ +S S S AT+SE + S T S S
Sbjct: 203 TSSGASTATNSESRTTSNGAGTATNS--ESSTTSSGASTATNSESSTPSSGAGTATNSES 260
Query: 764 GHGQAGHHQQSHQESARDRSGERSRRSGSFLYQVSTHKQSESSHGWTGPSTGVRQGSHHE 823
+G ++ ES+ SG +ST SESS +G +T
Sbjct: 261 STTSSGAGTATNSESSTVSSG------------ISTVTNSESSTPSSGANTAT------- 301
Query: 824 QARDNSRHSASQDGQDTIRGHPGS--SRRGRQGSHHEQSVDRSGHSGSHHSH--TTSQGR 879
NS S + G +T S S ++ E S SG S + +S TTS G
Sbjct: 302 ----NSESSTTSSGANTATNSDSSTTSSGASTATNSESSTTSSGASTATNSESSTTSSGA 357
Query: 880 SDASRGQSGSRSASRTTRNEEQSRDGSRHSGSRHHEASSHADISRHSQAGQGQSEGSRTS 939
S A+ SGS + S T S + S SS A + S++ S S +
Sbjct: 358 STATN--SGSSTTSSGT---------STATNSESSTVSSGASTATTSESSTTSSGASTAT 406
Query: 940 RRQGSSVSQDSDSEGHSEDSERWSGSASRNHRGSAQEQSRHGSRHPRSHHEDRAGHGHSA 999
+ S+VS + + +SE S SG+ + + GS+ + G+ H HSA
Sbjct: 407 NSESSTVSSGASTATNSESSTTSSGANTATNSGSSVTSAGSGTAALTGMHTT----SHSA 462
Query: 1000 DSSRQSGTP 1008
++ P
Sbjct: 463 STAVSEAKP 471
Score = 84.3 bits (207), Expect = 2e-15
Identities = 107/458 (23%), Positives = 183/458 (39%), Gaps = 29/458 (6%)
Query: 1317 ASHGHSADSSRQSGTHHTESSSHGQAVSSHEQARSSPGERHGSRHQQSADSSRHSGIGHR 1376
A+ G S SS S ++ SS VS+ + SS S S + SGI
Sbjct: 31 ANTGSSVISSGASTATNSGSSVTSSGVSTATISGSSVTSNGVSIVTNSEFHTTSSGI--- 87
Query: 1377 QASSAVRDSGHRGSSGSQV-TNSEGHSEDSD----TQSVSAHGQAGPHQQSHKESARGQS 1431
S+A SSG + TNSE + S T S S+ +G ++ +S+ S
Sbjct: 88 --STATNSEFSTVSSGISIATNSESSTTSSGASTATNSESSTPSSGASTATNSDSSTTSS 145
Query: 1432 GESSGRSRSFLYQVSSHEQSESTHGQTAPSTGGRQGSRHEQARNSSRHSASQDGQDTIRG 1491
G S+ + +S E S +T+ +++ ++ G + + ++ S +++ ++
Sbjct: 146 GASTATNSDS--STTSSEASTATNSESSTTSSGASTATNSESSTVSSRASTATNSESSTT 203
Query: 1492 HPGSSRGGRQGSYHEQSVDRSGHSGYHHSHTTPQGRSDASHGQSGPRSASRQTRNEEQSG 1551
G+S S + + +G + S TT G S A++ +S S+ T +S
Sbjct: 204 SSGASTATNSES--RTTSNGAGTATNSESSTTSSGASTATNSESSTPSSGAGTATNSESS 261
Query: 1552 DGSRHSGSRHHEPSTRAGSSRHSQVGQGE----SAGSKTSRRQGSSVSQDRDSEGHSEDS 1607
S +G+ + S+ SS S V E S+G+ T+ SS + + + DS
Sbjct: 262 TTSSGAGTATNSESSTV-SSGISTVTNSESSTPSSGANTATNSESSTTSSGANTATNSDS 320
Query: 1608 ERRSESASRNHYGSAREQSRHGSRNPRSHQEDRASHGHSAESSRQSGTRHAETSSGGQAA 1667
S AS S + G+ + + S G S ++ S T TSSG A
Sbjct: 321 STTSSGAS-TATNSESSTTSSGASTATNSESSTTSSGASTATNSGSST----TSSGTSTA 375
Query: 1668 SSQEQARSSPGERHGSRHQQSADSSTDSGTGRRQDSSVVGDSGNRGSSGSQASDSEGHSE 1727
++ E + S G + + S SS S + S+V + +S S + S ++
Sbjct: 376 TNSESSTVSSGASTATTSESSTTSSGASTATNSESSTVSSGASTATNSESSTTSSGANTA 435
Query: 1728 ESDTQSVSAHGQ-----AGPHQQSHQESTRGQSGERSG 1760
+ SV++ G G H SH ST + G
Sbjct: 436 TNSGSSVTSAGSGTAALTGMHTTSHSASTAVSEAKPGG 473
Score = 84.0 bits (206), Expect = 3e-15
Identities = 119/521 (22%), Positives = 208/521 (39%), Gaps = 73/521 (14%)
Query: 3194 HSQAVQGQSEGSRRSRRQGSSVSQDSDSEGHSEDSERWSGSASRNHRGSVQEQSRHGSRH 3253
H +A +E S + S +S + + +S S SG ++ GS + +
Sbjct: 17 HLEAATNSNETSTSANTGSSVISSGASTATNSGSSVTSSGVSTATISGSSV------TSN 70
Query: 3254 PRSHHEDRAGHGHSADRSRQSGTRHAETSSGGQAASSHEQARSSPGERHGSRHQQSADSS 3313
S + H S+ S + + + SSG A++ E + +S G + + S SS
Sbjct: 71 GVSIVTNSEFHTTSSGISTATNSEFSTVSSGISIATNSESSTTSSGASTATNSESSTPSS 130
Query: 3314 RHSGIPRGQASSAVRDSRHWGSSGSQASDSEGHSEESDTQSVSGHGQAGPHQQSHQESAR 3373
G +++ DS S S A++S+ + S+ + + + ES+
Sbjct: 131 -------GASTATNSDSSTTSSGASTATNSDSSTTSSEASTAT-----------NSESST 172
Query: 3374 DRSGGRSG---RSGSFLYQVSTHEQSESAHGRTRTSTGRRQGSHHEQARDSSRHSASQEG 3430
SG + S + + ST SES+ TS+G ++ E SR +++ G
Sbjct: 173 TSSGASTATNSESSTVSSRASTATNSESS----TTSSGASTATNSE-----SRTTSNGAG 223
Query: 3431 QDTIRGHPGSSRRGRQGSHYEQSVDRSGHSGSHHSH--TTSQGRSDASRGQSGSRSASRQ 3488
T +S ++ E S SG + +S TTS G A+ +S + S+
Sbjct: 224 TATNSESSTTSSGASTATNSESSTPSSGAGTATNSESSTTSSGAGTATNSESSTVSSGIS 283
Query: 3489 T-RNDEQSGDGSRHSWSHHHEASTQ---ADSSRHSQSGQGQSAGPRTSRNQGSSVSQDSD 3544
T N E S S + + + E+ST A+++ +S S S + ++ S+ S +
Sbjct: 284 TVTNSESSTPSSGANTATNSESSTTSSGANTATNSDSSTTSSGASTATNSESSTTSSGAS 343
Query: 3545 SQGHSEDSERWSGSASRNHRGSAQEQSRDGSRHPTSHHEDRAGHGHSAESSRQSGTHHAE 3604
+ +SE S SG+++ + GS+ S G S ++ +S T
Sbjct: 344 TATNSESSTTSSGASTATNSGSSTTSS-----------------GTSTATNSESSTV--- 383
Query: 3605 NSSGGQAASSHEQARSSAGERHGSHHQQSADSSRHSGIGHGQASSAVRDSGHRGSSGSQA 3664
SSG A++ E + +S+G ++ + S SS AS+A SSG+
Sbjct: 384 -SSGASTATTSESSTTSSGASTATNSESSTVSSG--------ASTATNSESSTTSSGANT 434
Query: 3665 SDSEGHSEDSDTQSVSAHGQAGPHQQSHQESTRGRSAGRSG 3705
+ + G S S +A G H SH ST A G
Sbjct: 435 ATNSGSSVTSAGSGTAA--LTGMHTTSHSASTAVSEAKPGG 473
Score = 84.0 bits (206), Expect = 3e-15
Identities = 99/387 (25%), Positives = 159/387 (41%), Gaps = 30/387 (7%)
Query: 295 SRVSQDRDSEGHSEDSERHSGSASRNHHGSAWEQSRDGSRHPRSHDEDRASHGHSADSSR 354
S VS +SE S SG+++ + S+ S G+ + D S G S ++
Sbjct: 96 STVSSGISIATNSESSTTSSGASTATNSESSTPSS--GASTATNSDSSTTSSGASTATNS 153
Query: 355 QSGTRHAETSSRGQTASSHEQARSSPGERHGSGHQQSADSSRHSATGRGQASSAVSDRGH 414
S T TSS TA++ E + +S G + + S SSR S ++S+ S
Sbjct: 154 DSST----TSSEASTATNSESSTTSSGASTATNSESSTVSSRASTATNSESSTTSSGAST 209
Query: 415 RGSSGSQA-SDSEGHSENSDTQSVS-GHGKAGLRQQSHQESTRGRSGERSGRSGSSLYQV 472
+S S+ S+ G + NS++ + S G A + S S G + + SS
Sbjct: 210 ATNSESRTTSNGAGTATNSESSTTSSGASTATNSESSTPSSGAGTATNSESSTTSSGAGT 269
Query: 473 STHEQPDSAHGRTGTSTGGRQGSHHEQARDS--SRHSASQEGQDTIRGHPGS--SRGGRQ 528
+T+ + + T T + A + S S + G +T S S G
Sbjct: 270 ATNSESSTVSSGISTVTNSESSTPSSGANTATNSESSTTSSGANTATNSDSSTTSSGAST 329
Query: 529 GSHHEQSVNRSGHSGSHHSH--TTSQGRSDASHGQSGSRSASRQTRNEEQSGDGTRHSGS 586
++ E S SG S + +S TTS G S A++ SGS + S T S T SG
Sbjct: 330 ATNSESSTTSSGASTATNSESSTTSSGASTATN--SGSSTTSSGTSTATNSESSTVSSG- 386
Query: 587 RHHEASSQADSSRHSQVGQGQSSGPRTSRNQGSSVSQDSDSQGHSEDSERWSGSASRNHH 646
+S A +S S G S+ + ++ S+VS + + +SE S SG+ + +
Sbjct: 387 -----ASTATTSESSTTSSGAST---ATNSESSTVSSGASTATNSESSTTSSGANTATNS 438
Query: 647 GSAQEQSRDGS-----RHPRSHHEDRA 668
GS+ + G+ H SH A
Sbjct: 439 GSSVTSAGSGTAALTGMHTTSHSASTA 465
Score = 83.6 bits (205), Expect = 4e-15
Identities = 108/482 (22%), Positives = 189/482 (39%), Gaps = 41/482 (8%)
Query: 2230 SSGPRTSRPRGSSVSQDSDSEGHSEDSERRSGSASRNHHGSAQEQSRDGSRHPRSHHEDR 2289
S+ TS GSSV S + S S S + S S S
Sbjct: 24 SNETSTSANTGSSVISSGASTATNSGSSVTSSGVSTATISGSSVTSNGVSIVTNSEF--- 80
Query: 2290 AGHGHSAESSRQSGTHHAENSSGGQAASSHEQARSSAGERHGSHHQQSADSSRHSGIGHG 2349
H S+ S + + + SSG A++ E + +S+G ++ + S SS G
Sbjct: 81 --HTTSSGISTATNSEFSTVSSGISIATNSESSTTSSGASTATNSESSTPSS-------G 131
Query: 2350 QASSAVRDSGHRGSSGSQASDSEGHSEDSDTQSVSAHGQAGPHQQSHQESTRGRSAGRSG 2409
+++ DS S S A+ +SD+ + S+ + +S S+ G S +
Sbjct: 132 ASTATNSDSSTTSSGASTAT-------NSDSSTTSSEASTATNSESSTTSS-GASTATNS 183
Query: 2410 RSGSFLYQVSTHEQSESAHGRTGTSTGGRQGSHHKQARDSSRHSTSQEGQDTIHGHPGSS 2469
S + + ST SES+ +G ST SR +++ G T +S
Sbjct: 184 ESSTVSSRASTATNSESSTTSSGASTA---------TNSESRTTSNGAGTATNSESSTTS 234
Query: 2470 SGGRQGSHYEQLVDRS--GHSGSHHSHTTSQGRSDASHGHSGSRSASRQTRNDEQSGDGS 2527
SG ++ E S G + + S TTS G A++ S + S+ T + +S S
Sbjct: 235 SGASTATNSESSTPSSGAGTATNSESSTTSSGAGTATNSESSTVSSGISTVTNSESSTPS 294
Query: 2528 RHSGSRHHEASSRADSSGHSQVGQGQ---SEGPRTSRNWGSS-FSQDSDSQGHSEDSERW 2583
+ + + SS S ++ S G T+ N SS S + + +SE S
Sbjct: 295 SGANTATNSESSTTSSGANTATNSDSSTTSSGASTATNSESSTTSSGASTATNSESSTTS 354
Query: 2584 SGSASRNHHGSAQEQLRDGSRHPRSHQEDRAGHGHSADSSRQSGTRHTQTSSGGQAASSH 2643
SG+++ + GS+ G+ + + G S ++ +S T TSSG A++
Sbjct: 355 SGASTATNSGSSTTS--SGTSTATNSESSTVSSGASTATTSESST----TSSGASTATNS 408
Query: 2644 EQARSSAGERHGSHHQQSADSSRHSGIGHGQASSAVRDSGHRGYSGSQASDNEGHSEDSD 2703
E + S+G ++ + S SS + + +S SG +G + + + S+
Sbjct: 409 ESSTVSSGASTATNSESSTTSSGANTATNSGSSVTSAGSGTAALTGMHTTSHSASTAVSE 468
Query: 2704 TQ 2705
+
Sbjct: 469 AK 470
Score = 83.2 bits (204), Expect = 5e-15
Identities = 98/456 (21%), Positives = 183/456 (40%), Gaps = 35/456 (7%)
Query: 1520 SHTTPQGRSDASHGQSGPRSASRQTRNEEQSGDGSRH----SGSRHHEPSTRAGSSRHSQ 1575
S G S A++ S S+ T S S + S H S+ ++ +S+
Sbjct: 35 SSVISSGASTATNSGSSVTSSGVSTATISGSSVTSNGVSIVTNSEFHTTSSGISTATNSE 94
Query: 1576 VGQGESAGSKTSRRQGSSVSQDRDSEGHSEDSERRSESASRNHYGSAREQSRHGSRNPRS 1635
S S + + S+ S + +SE S S +++ + S+ S S
Sbjct: 95 FSTVSSGISIATNSESSTTSSGASTATNSESSTPSSGASTATNSDSSTTSSG------AS 148
Query: 1636 HQEDRASHGHSAESSRQSGTRHAETSSGGQAASSQEQARSSPGERHGSRHQQSADSSTDS 1695
+ S S+E+S + + + TSSG A++ E + S + + +S+ +S+ +
Sbjct: 149 TATNSDSSTTSSEASTATNSESSTTSSGASTATNSESSTVS-SRASTATNSESSTTSSGA 207
Query: 1696 GTGRRQDSSVVGDSGNRGSSGSQASDSEGHSEESDTQSVSAHGQAGPHQQSHQESTRGQS 1755
T +S + ++ ++ S G S ++++S + AG S +T +
Sbjct: 208 STATNSESRTTSNGAGTATNSESSTTSSGASTATNSESSTPSSGAGTATNSESSTTSSGA 267
Query: 1756 GERSGRSGSFLYQ-VSTHEQSESAHGRTGPSTGGRQRSRHEQARDSSRHSASQEGQDTIR 1814
G + S + +ST SES+ PS+G + E + SS + + +
Sbjct: 268 GTATNSESSTVSSGISTVTNSESST----PSSGANTATNSESSTTSSGANTATNSDSST- 322
Query: 1815 GHPGSSRGGRQGSHYEQSVDSSGHSGSHHSHTTSQERSDVSRGQSGSRSVSRQTRNEKQS 1874
+S G ++ E S SSG S + +S +++ + SGS + S T S
Sbjct: 323 ----TSSGASTATNSESSTTSSGASTATNSESSTTSSGASTATNSGSSTTSSGTSTATNS 378
Query: 1875 GDGSRHSGSRHHEASSRADSSRHSQVGQGQSSGPRTSRNQGSSVSQDSDSQGHSEDSERW 1934
+ SG +S A +S S G S+ + ++ S+VS + + +SE S
Sbjct: 379 ESSTVSSG------ASTATTSESSTTSSGAST---ATNSESSTVSSGASTATNSESSTTS 429
Query: 1935 SGSASRNHLGSAWEQSRDGS-----RHPGSHHEDRA 1965
SG+ + + GS+ + G+ H SH A
Sbjct: 430 SGANTATNSGSSVTSAGSGTAALTGMHTTSHSASTA 465
Score = 82.4 bits (202), Expect = 8e-15
Identities = 111/476 (23%), Positives = 182/476 (38%), Gaps = 24/476 (5%)
Query: 3506 HHEASTQA-DSSRHSQSGQGQ-SAGPRTSRNQGSSVSQDSDSQGHSEDSERWSGSASRNH 3563
H EA+T + ++S + +G S+G T+ N GSSV+ S S S S
Sbjct: 17 HLEAATNSNETSTSANTGSSVISSGASTATNSGSSVTSSGVSTATISGSSVTSNGVSIVT 76
Query: 3564 RGSAQEQSRDGSRHPTSHHEDRAGHGHSAESSRQSGTHHAENSSGGQAASSHEQARSSAG 3623
S G T+ G S ++ +S T SSG A++ E + S+G
Sbjct: 77 NSEFHTTS-SGISTATNSEFSTVSSGISIATNSESST----TSSGASTATNSESSTPSSG 131
Query: 3624 ERHGSHHQQSADSSRHSGIGHGQASSAVRD-SGHRGSSGSQASDSEGHSEDSDTQSVSAH 3682
++ S SS S + +S+ + S S S S + +S++ +VS+
Sbjct: 132 ASTATNSDSSTTSSGASTATNSDSSTTSSEASTATNSESSTTSSGASTATNSESSTVSSR 191
Query: 3683 GQAGPHQQSHQESTRGRSAGRSGRSGSFLYQVSTHEQSESAHGRAGPSTGGRQGSRHEQA 3742
+ +S S+ G S + S + T SES+ +G ST
Sbjct: 192 ASTATNSESSTTSS-GASTATNSESRTTSNGAGTATNSESSTTSSGASTA---------T 241
Query: 3743 RDSSRHSASQEGQDTIRGHPGSRRGGRQGSYHEQSVDRSGHSG--SHHSHTTSQGRSDAS 3800
S +S G T + G + E S SG S + S T S G + A+
Sbjct: 242 NSESSTPSSGAGTATNSESSTTSSGAGTATNSESSTVSSGISTVTNSESSTPSSGANTAT 301
Query: 3801 HGQSGSRSASRETR-NEEQSGDGSRHSGSRHHEASTQADSSRHSQSGQGE--SAGSRRSR 3857
+ +S + S+ T N + S S S + + E+ST + + + + + S+G+ +
Sbjct: 302 NSESSTTSSGANTATNSDSSTTSSGASTATNSESSTTSSGASTATNSESSTTSSGASTAT 361
Query: 3858 RQGSSVSQDSDSEAYPEDSERRSESASRNHHGSSREQSRDGSRHPGSSHRDTASHVQSSP 3917
GSS + S A +S S AS S S G+ +S T S S+
Sbjct: 362 NSGSSTTSSGTSTATNSESSTVSSGASTATTSESSTTS-SGASTATNSESSTVSSGASTA 420
Query: 3918 VQSDSSTAKEHGHFSSLSQDSAYHSGIQSRGSPHSSSSYHYQSEGTERQKGQSGLV 3973
S+SST + ++ S S +G + ++ H S K LV
Sbjct: 421 TNSESSTTSSGANTATNSGSSVTSAGSGTAALTGMHTTSHSASTAVSEAKPGGSLV 476
Score = 82.4 bits (202), Expect = 8e-15
Identities = 115/499 (23%), Positives = 192/499 (38%), Gaps = 58/499 (11%)
Query: 1603 HSEDSERRSESASRNHYGS------AREQSRHGSRNPRSHQEDRASHGHSAESSRQSGTR 1656
H E + +E+++ + GS A + GS S G S S+ S
Sbjct: 17 HLEAATNSNETSTSANTGSSVISSGASTATNSGSSVTSSGVSTATISGSSVTSNGVSIVT 76
Query: 1657 HAE---TSSGGQAASSQEQARSSPGERHGSRHQQSADSSTDSGTGRRQDSSVVGDSGNRG 1713
++E TSSG A++ E + S G + + +S+ +S+ + T +SS +
Sbjct: 77 NSEFHTTSSGISTATNSEFSTVSSGISIAT-NSESSTTSSGASTATNSESSTPSSGASTA 135
Query: 1714 SSGSQASDSEGHSEESDTQSVSAHGQAGPHQQSHQESTR-GQSGERSGRSGSFLYQVSTH 1772
++ ++ S G S +++ S + +A S +T G S + S + + ST
Sbjct: 136 TNSDSSTTSSGASTATNSDSSTTSSEASTATNSESSTTSSGASTATNSESSTVSSRASTA 195
Query: 1773 EQSESAHGRTGPSTGGRQRSRHEQ----ARDSSRHSASQEGQDTIRGHPGS--SRGGRQG 1826
SES+ +G ST SR +S S + G T S S G
Sbjct: 196 TNSESSTTSSGASTATNSESRTTSNGAGTATNSESSTTSSGASTATNSESSTPSSGAGTA 255
Query: 1827 SHYEQSVDSSGHSGSHHSHTTSQERSDVSRGQSGSRSVSRQTRNEKQSGDGSRHSGSRHH 1886
++ E S SSG + T+ E S VS SG +V+ + SG + + S
Sbjct: 256 TNSESSTTSSGAGTA-----TNSESSTVS---SGISTVTNSESSTPSSGANTA-TNSESS 306
Query: 1887 EASSRADSSRHSQVGQGQSSGPRTSRNQGSSVSQDSDSQGHSEDSERWSGSASRNHLGSA 1946
SS A+++ +S S + ++ S+ S + + +SE S SG+++ + GS
Sbjct: 307 TTSSGANTATNSDSSTTSSGASTATNSESSTTSSGASTATNSESSTTSSGASTATNSGS- 365
Query: 1947 WEQSRDGSRHPGSHHEDRAGHGHSADSSRQSGTRHTESSSRGQAASSHEQARSSAGERHG 2006
S SS S ++ESS+ AS+ + SS
Sbjct: 366 -----------------------STTSSGTSTATNSESSTVSSGASTATTSESSTTSSGA 402
Query: 2007 SHHQLQSADSSRHSGIGHGQASSAVRDSGHRGYSGSQASDSEGHSEDSDTQSVSAQGKAG 2066
S +A +S S + G AS+A SG+ + + G S S +A G
Sbjct: 403 S-----TATNSESSTVSSG-ASTATNSESSTTSSGANTATNSGSSVTSAGSGTAAL--TG 454
Query: 2067 PHQQSHKESARGQSGESSG 2085
H SH S + G
Sbjct: 455 MHTTSHSASTAVSEAKPGG 473
Score = 82.0 bits (201), Expect = 1e-14
Identities = 113/451 (25%), Positives = 188/451 (41%), Gaps = 42/451 (9%)
Query: 2741 QVSTHEQSESSHGWTGPSTRGRQGSRHEQAQDSSRHSASQDGQDTIRGHPGSSRGGRQGY 2800
+ ST + SS +G ST GS + S+ TI G +S G
Sbjct: 26 ETSTSANTGSSVISSGASTATNSGSSVTSSGVSTA---------TISGSSVTSNGVSIVT 76
Query: 2801 HHEHSVDSSGHSGSHHSH--TTSQGRSDASRGQSGSRSASRTTR-NEEQSGDGSRHSGSR 2857
+ E SSG S + +S T S G S A+ +S + S+ +T N E S S S +
Sbjct: 77 NSEFHTTSSGISTATNSEFSTVSSGISIATNSESSTTSSGASTATNSESSTPSSGASTAT 136
Query: 2858 HHEASTH---ADISRHSQAVQGQSEGSRRSRRQGSSVSQDSDSEGHSEDSERWSGSASRN 2914
+ ++ST A + +S + SE S + + S+ S + + +SE S S +++
Sbjct: 137 NSDSSTTSSGASTATNSDSSTTSSEASTATNSESSTTSSGASTATNSESSTVSSRASTAT 196
Query: 2915 HHGSAQEQLRDGSRHPRSHQEDRAGHGHSADSSRQSGTRHTQTSSGGQAASSHEQARSSA 2974
+ S+ G+ + + +G ++ +S T TSSG A++ E + S+
Sbjct: 197 NSESSTTS--SGASTATNSESRTTSNGAGTATNSESST----TSSGASTATNSESSTPSS 250
Query: 2975 GERHGSHHQQSADSSRHSGIGHGQASSAVRDSGHRGYSGSQASDNEGHSEDSD--TQSVS 3032
G ++ + S SS G G A+++ + G S S++ S ++ T S S
Sbjct: 251 GAGTATNSESSTTSS-----GAGTATNSESSTVSSGISTVTNSESSTPSSGANTATNSES 305
Query: 3033 AHGQAGSHQQSHQES---ARGRSGETSGHSGSFLYQVSTHEQSESSHGWTGPSTRGRQGS 3089
+ +G++ ++ +S + G S T+ S + ST SESS +G ST GS
Sbjct: 306 STTSSGANTATNSDSSTTSSGASTATNSESSTTSSGASTATNSESSTTSSGASTATNSGS 365
Query: 3090 RHEQAQDSSRHSASQYGQDTIRGHPGSSRGGRQGYHHEHSVDSSGHSGSHHSH--TTSQG 3147
S +A+ T+ S G E S SSG S + +S T S G
Sbjct: 366 ---STTSSGTSTATNSESSTV------SSGASTATTSESSTTSSGASTATNSESSTVSSG 416
Query: 3148 RSDASRGQSGSRSASRTTRNEEQSGDSSRHS 3178
S A+ +S + S+ T S +S S
Sbjct: 417 ASTATNSESSTTSSGANTATNSGSSVTSAGS 447
Score = 82.0 bits (201), Expect = 1e-14
Identities = 102/445 (22%), Positives = 168/445 (37%), Gaps = 26/445 (5%)
Query: 1581 SAGSKTSRRQGSSVSQDRDSEGHSEDSERRSESASRNHYGSAREQSRHGSRNPRSHQEDR 1640
S+G+ T+ GSSV+ S S S S S + G + +
Sbjct: 39 SSGASTATNSGSSVTSSGVSTATISGSSVTSNGVSIVT-NSEFHTTSSGISTATNSEFST 97
Query: 1641 ASHGHSAESSRQSGTRHAETSSGGQAASSQEQARSSPGERHGSRHQQSADSSTDSGTGRR 1700
S G S ++ +S T TSSG A++ E + S G + + S+ +S+ + T
Sbjct: 98 VSSGISIATNSESST----TSSGASTATNSESSTPSSGASTAT-NSDSSTTSSGASTATN 152
Query: 1701 QDSSVVGDSGNRGSSGSQASDSEGHSEESDTQSVSAHGQAGPHQQSHQESTR-GQSGERS 1759
DSS + ++ ++ S G S ++++S + +A S +T G S +
Sbjct: 153 SDSSTTSSEASTATNSESSTTSSGASTATNSESSTVSSRASTATNSESSTTSSGASTATN 212
Query: 1760 GRSGSFLYQVSTHEQSESAHGRTGPSTGGRQRSRHEQARDSSRHSASQEGQDTIRGHPGS 1819
S + T SES+ +G ST S +S G T +
Sbjct: 213 SESRTTSNGAGTATNSESSTTSSGASTA---------TNSESSTPSSGAGTATNSESSTT 263
Query: 1820 SRGGRQGSHYEQSVDSSG-------HSGSHHSHTTSQERSDVSRGQSGSRSVSRQTRNEK 1872
S G ++ E S SSG S + S + S+ S SG+ + + +
Sbjct: 264 SSGAGTATNSESSTVSSGISTVTNSESSTPSSGANTATNSESSTTSSGANTATNSDSSTT 323
Query: 1873 QSGDGSRHSGSRHHEASSRADSSRHSQVGQGQSSGPRTSRNQGSSVSQDSDSQGHSEDSE 1932
SG S + S SS A ++ +S+ SSG T+ N GSS + S + +S
Sbjct: 324 SSG-ASTATNSESSTTSSGASTATNSE-SSTTSSGASTATNSGSSTTSSGTSTATNSESS 381
Query: 1933 RWSGSASRNHLGSAWEQSRDGSRHPGSHHEDRAGHGHSADSSRQSGTRHTESSSRGQAAS 1992
S AS + S S S G S ++ +S T + +++ + S
Sbjct: 382 TVSSGASTATTSESSTTSSGASTATNS-ESSTVSSGASTATNSESSTTSSGANTATNSGS 440
Query: 1993 SHEQARSSAGERHGSHHQLQSADSS 2017
S A S G H SA ++
Sbjct: 441 SVTSAGSGTAALTGMHTTSHSASTA 465
Score = 81.6 bits (200), Expect = 1e-14
Identities = 115/503 (22%), Positives = 194/503 (38%), Gaps = 55/503 (10%)
Query: 588 HHEASSQA-DSSRHSQVGQGQ-SSGPRTSRNQGSSVSQDSDSQGHSEDSERWSGSASRNH 645
H EA++ + ++S + G SSG T+ N GSSV+ S S S S
Sbjct: 17 HLEAATNSNETSTSANTGSSVISSGASTATNSGSSVTSSGVSTATISGSSVTSNGVSIVT 76
Query: 646 HGSAQEQSRDGSRHPRSHHEDRAGHGHSADSSRKSGTRHTQNSSSGQAASSHEQARSSAG 705
+ S S S + A +S S T SS A++ E + S+G
Sbjct: 77 NSEFHTTSSGISTATNSEFSTVSSGISIATNSESSTT-----SSGASTATNSESSTPSSG 131
Query: 706 ERHGSRHQLQSADSSRHSGTGHGQASSAVRDSGHRGSSGSQATDSEGHSEDSDTQSVSGH 765
+A +S S T G +++ DS S S AT+SE + S + +
Sbjct: 132 A--------STATNSDSSTTSSGASTATNSDSSTTSSEASTATNSESSTTSSGASTAT-- 181
Query: 766 GQAGHHQQSHQESARDRSGERSRRSGSFLYQVSTHKQSESSHGWTGPSTGVRQGSHHEQA 825
+ +S S+R ST SESS +G ST + ++
Sbjct: 182 -----NSESSTVSSR----------------ASTATNSESSTTSSGASTAT-----NSES 215
Query: 826 RDNSRHSASQDGQDTIRGHPGSSRRGRQGSHHEQSVDRSGHSGSHHSHTTSQGRSDASRG 885
R S + + ++ G+S S S +G + + S TTS G A+
Sbjct: 216 RTTSNGAGTATNSESSTTSSGASTATNSESSTPSS--GAGTATNSESSTTSSGAGTATNS 273
Query: 886 QSGSRSAS-RTTRNEEQSRDGSRHSGSRHHEAS---SHADISRHSQAGQGQSEGSRTSRR 941
+S + S+ T N E S S + + + E+S S A+ + +S + S S +
Sbjct: 274 ESSTVSSGISTVTNSESSTPSSGANTATNSESSTTSSGANTATNSDSSTTSSGASTATNS 333
Query: 942 QGSSVSQDSDSEGHSEDSERWSGSASRNHRGSAQEQSRHGSRHPRSHHEDRAGHGHSADS 1001
+ S+ S + + +SE S SG+++ + GS+ S G+ + G S +
Sbjct: 334 ESSTTSSGASTATNSESSTTSSGASTATNSGSSTTSS--GTSTATNSESSTVSSGASTAT 391
Query: 1002 SRQSGTPHAETSSGGQAASSHEQARSSPGERHGSRHQQSADSSRHSGIPRRQASSAVRDS 1061
+ +S T TSSG A++ E + S G + + S SS + +S S
Sbjct: 392 TSESST----TSSGASTATNSESSTVSSGASTATNSESSTTSSGANTATNSGSSVTSAGS 447
Query: 1062 GHWGSSGSQASDSEGHSEESDTQ 1084
G +G + + S+ +
Sbjct: 448 GTAALTGMHTTSHSASTAVSEAK 470
Score = 80.9 bits (198), Expect = 2e-14
Identities = 109/480 (22%), Positives = 185/480 (38%), Gaps = 48/480 (10%)
Query: 1828 HYEQSVDSSGHSGSHHSHTTSQERSDVSRGQSGSRSVSRQTRNEKQSGDGSRHSG----- 1882
H E + +S+ S S ++ ++ + SGS S SG +G
Sbjct: 17 HLEAATNSNETSTSANTGSSVISSGASTATNSGSSVTSSGVSTATISGSSVTSNGVSIVT 76
Query: 1883 -SRHHEASSRADSSRHSQVGQGQSSGPRTSRNQGSSVSQDSDSQGHSEDSERWSGSASRN 1941
S H SS ++ +S+ S + ++ S+ S + + +SE S SG+++
Sbjct: 77 NSEFHTTSSGISTATNSEFSTVSSGISIATNSESSTTSSGASTATNSESSTPSSGASTAT 136
Query: 1942 HLGSAWEQSRDGSRHPGSHHEDRAGHGHSADSSRQSGTRHTESSSRGQAASSHEQARSSA 2001
+ S+ S + S SS S ++ESS+ AS+ + SS
Sbjct: 137 NSDSSTTSSGASTA---------TNSDSSTTSSEASTATNSESSTTSSGASTATNSESST 187
Query: 2002 GERHGSHHQLQSADSSRHSGIGHGQASSAVRDSGHRGYSGSQASDSEGHSEDSDTQSVSA 2061
S S S+ SG S + S G + + S + + T S S+
Sbjct: 188 VSSRAST-ATNSESSTTSSGASTATNSESRTTSNGAGTATNSESSTTSSGASTATNSESS 246
Query: 2062 QGKAGPHQQSHKESARGQSGE---SSGRSGSFLYQVSTHEQSESTHGQSAPSTGGRQGSH 2118
+G ++ ES+ SG ++ S + +ST SES S PS+G ++
Sbjct: 247 TPSSGAGTATNSESSTTSSGAGTATNSESSTVSSGISTVTNSES----STPSSGANTATN 302
Query: 2119 YDQAQDSS-RHSASQEGQDTIRGHPGPSRGGRQGSHQEQSVDRSGHSGSHHSH--TTSQG 2175
+ + SS ++A+ T S G ++ E S SG S + +S TTS G
Sbjct: 303 SESSTTSSGANTATNSDSST------TSSGASTATNSESSTTSSGASTATNSESSTTSSG 356
Query: 2176 RSDASRGQSGSRSASRKTYDKEQSGDGSRHSGSHHHEASSWADSSRHSLVGQGQSSGPRT 2235
S A+ S + S+ T +S S +S A +S S G S+
Sbjct: 357 ASTATNSGSSTTSSGTSTATNSESSTVS--------SGASTATTSESSTTSSGAST---A 405
Query: 2236 SRPRGSSVSQDSDSEGHSEDSERRSGSASRNHHGSAQEQSRDGS-----RHPRSHHEDRA 2290
+ S+VS + + +SE S SG+ + + GS+ + G+ H SH A
Sbjct: 406 TNSESSTVSSGASTATNSESSTTSSGANTATNSGSSVTSAGSGTAALTGMHTTSHSASTA 465
Score = 80.1 bits (196), Expect = 4e-14
Identities = 112/513 (21%), Positives = 193/513 (37%), Gaps = 57/513 (11%)
Query: 925 HSQAGQGQSEGSRTSRRQGSSVSQDSDSEGHSEDSERWSGSASRNHRGSAQEQSRHGSRH 984
H +A +E S ++ S +S + + +S S SG ++ GS+ + +
Sbjct: 17 HLEAATNSNETSTSANTGSSVISSGASTATNSGSSVTSSGVSTATISGSSV------TSN 70
Query: 985 PRSHHEDRAGHGHSADSSRQSGTPHAETSSGGQAASSHEQARSSPGERHGSRHQQSADSS 1044
S + H S+ S + + + SSG A++ E + +S G + + S SS
Sbjct: 71 GVSIVTNSEFHTTSSGISTATNSEFSTVSSGISIATNSESSTTSSGASTATNSESSTPSS 130
Query: 1045 RHSGIPRRQASSAVRDSGHWGSSGSQASDSEGHSE-ESDTQSVSGHGQDGPHQQSHQESA 1103
S +S+ + +S S + SE + S++ + S + +S S+
Sbjct: 131 GASTATNSDSSTTSSGASTATNSDSSTTSSEASTATNSESSTTSSGASTATNSESSTVSS 190
Query: 1104 RDWSGGRSGRSGSFIYQVSTHEQSESAHGRTRTSTGRRQGSHHEQARDSSRHSASQEGQD 1163
R S + S + ST SES RT TS G ++ E + SS S + +
Sbjct: 191 RA-STATNSESSTTSSGASTATNSES---RT-TSNGAGTATNSESSTTSSGASTATNSES 245
Query: 1164 TIRAHPGSRRGGRQGSHHEQSVDRSGHSGSHHSHTTSQGRSDASHGQSGSRSASRQTRKD 1223
+ P S G S + +G + + S T S G S ++ +S + S+ T +
Sbjct: 246 ST---PSSGAGTATNSESSTTSSGAGTATNSESSTVSSGISTVTNSESSTPSSGANTATN 302
Query: 1224 KQSGDGSRHSGSRHHEAASWADSSRHSQVGQEQSSGSRTSRHQGSSVSQDSDSERHSDDS 1283
+S S S A+++ +S S S + + S+ S + + +S+ S
Sbjct: 303 SESSTTS-----------SGANTATNSDSSTTSSGASTATNSESSTTSSGASTATNSESS 351
Query: 1284 ERLSGSASRNHHGSSREQSRDGSRHPGFHQEDRASHGHSADSSRQSGTHHTESSSHGQAV 1343
SG+++ + GS S SS S ++ESS+
Sbjct: 352 TTSSGASTATNSGS------------------------STTSSGTSTATNSESSTVSSGA 387
Query: 1344 SSHEQARSSPGERHGSRHQQSADSSRHSGIGHRQASSAVRDSGHRGSSGSQVTNSEGHSE 1403
S+ + SS S S S+ SG AS+A SSG+ + G S
Sbjct: 388 STATTSESSTTSSGASTATNSESSTVSSG-----ASTATNSESSTTSSGANTATNSGSSV 442
Query: 1404 DSDTQSVSAHGQAGPHQQSHKESARGQSGESSG 1436
S +A G H SH S + G
Sbjct: 443 TSAGSGTAA--LTGMHTTSHSASTAVSEAKPGG 473
Score = 80.1 bits (196), Expect = 4e-14
Identities = 118/463 (25%), Positives = 185/463 (39%), Gaps = 38/463 (8%)
Query: 2425 ESAHGRTGTSTGGRQGSHHKQARDSSRHSTSQEGQDTIHGHPGSSSGGRQGSHYEQLVDR 2484
E+A TST GS + SS ST+ T G +SSG + V
Sbjct: 19 EAATNSNETSTSANTGS----SVISSGASTA-----TNSGSSVTSSGVSTATISGSSVTS 69
Query: 2485 SGHSGSHHS--HTTSQGRSDASHGHSGSRSASRQ-TRNDEQSGDGSRHSGSRHHEASSRA 2541
+G S +S HTTS G S A++ + S+ N E S S S + + E+S+
Sbjct: 70 NGVSIVTNSEFHTTSSGISTATNSEFSTVSSGISIATNSESSTTSSGASTATNSESST-- 127
Query: 2542 DSSGHSQVGQGQSEGPRTSRNWGSSFSQDSDSQGHSEDSERWSGSASRNHHGSAQEQLRD 2601
SSG S S ++ + G+S + +SDS S ++ + S S A
Sbjct: 128 PSSGASTATNSDS----STTSSGASTATNSDSSTTSSEASTATNSESSTTSSGASTATNS 183
Query: 2602 GSRHPRSHQEDRAGHGHSADSSRQSGTRHTQ---TSSGGQAASSHEQARSSAGERHGSHH 2658
S S S SS S +++ TS+G A++ E + +S+G ++
Sbjct: 184 ESSTVSSRASTATNSESSTTSSGASTATNSESRTTSNGAGTATNSESSTTSSGASTATNS 243
Query: 2659 QQSADSSRHSGIGHGQASSAVRDSGHRGYSGSQASDNEGHSEDSDTQSVSAHGQAGSHQQ 2718
+ S S SG G S + S G + + S + T S S+ +G++
Sbjct: 244 ESSTPS---SGAGTATNSESSTTSSGAGTATNSESSTVSSGISTVTNSESSTPSSGANTA 300
Query: 2719 SHQESARGRSG---ETSGHSGSFLYQVSTHEQSESSHGWTGPSTRGRQGSRHEQAQDSSR 2775
++ ES+ SG T+ S + ST SESS +G ST S S
Sbjct: 301 TNSESSTTSSGANTATNSDSSTTSSGASTATNSESSTTSSGASTATNSES---STTSSGA 357
Query: 2776 HSASQDGQDTIRGHPGSSRGGRQGYHHEHSVDSSGHS--GSHHSHTTSQGRSDASRGQSG 2833
+A+ G T +S G + E S SSG S + S TTS G S A+ +S
Sbjct: 358 STATNSGSST------TSSGTSTATNSESSTVSSGASTATTSESSTTSSGASTATNSESS 411
Query: 2834 SRSASRTTRNEEQSGDGSRHSGSRHHEASTHADISRHSQAVQG 2876
+ S+ +T +S S + + + S+ + A+ G
Sbjct: 412 TVSSGASTATNSESSTTSSGANTATNSGSSVTSAGSGTAALTG 454
Score = 79.7 bits (195), Expect = 5e-14
Identities = 101/442 (22%), Positives = 180/442 (40%), Gaps = 28/442 (6%)
Query: 2334 HQQSADSSRHSGIGHGQASSAVRDSGHRGS-SGSQASDSEGHSEDSDTQSVSAHGQAGPH 2392
H ++A +S + SS + + SGS + S + SV+++G +
Sbjct: 17 HLEAATNSNETSTSANTGSSVISSGASTATNSGSSVTSSGVSTATISGSSVTSNGVSIVT 76
Query: 2393 QQSHQESTRGRSAGRSGRSGSFLYQVSTHEQSESAHGRTGTSTGGRQGSHHKQARDSSRH 2452
++ G S + + +S SES+ +G ST +S
Sbjct: 77 NSEFHTTSSGISTATNSEFSTVSSGISIATNSESSTTSSGASTA-----------TNSES 125
Query: 2453 STSQEGQDTIHGHPGS--SSGGRQGSHYEQLVDRSGHSGSHHSH--TTSQGRSDASHGHS 2508
ST G T S SSG ++ + S S + +S TTS G S A++ S
Sbjct: 126 STPSSGASTATNSDSSTTSSGASTATNSDSSTTSSEASTATNSESSTTSSGASTATNSES 185
Query: 2509 GSRSASRQTR-NDEQSGDGSRHSGSRHHEASSRADSSGHSQVGQGQ--SEGPRTSRNWGS 2565
+ S+ T N E S S S + + E+ + ++ +G + + S G T+ N S
Sbjct: 186 STVSSRASTATNSESSTTSSGASTATNSESRTTSNGAGTATNSESSTTSSGASTATNSES 245
Query: 2566 SF-SQDSDSQGHSEDSERWSGSASRNHHGSAQEQLRDGSRHPRSHQEDRAGHGHSADSSR 2624
S S + + +SE S SG+ + + S + G + + G + ++
Sbjct: 246 STPSSGAGTATNSESSTTSSGAGTATN--SESSTVSSGISTVTNSESSTPSSGANTATNS 303
Query: 2625 QSGTRHTQTSSGGQAASSHEQARSSAGERHGSHHQQSADSSRHSGIGHGQASSAVRDSGH 2684
+S T TSSG A++ + + +S+G ++ + S SS S + ++S+ +
Sbjct: 304 ESST----TSSGANTATNSDSSTTSSGASTATNSESSTTSSGASTATNSESSTTSSGAST 359
Query: 2685 RGYSGSQ-ASDNEGHSEDSDTQSVSAHGQAGSHQQSHQESARGRSGETSGHSGSFLYQVS 2743
SGS S + +S++ +VS+ + +S S+ G S T+ S + S
Sbjct: 360 ATNSGSSTTSSGTSTATNSESSTVSSGASTATTSESSTTSS-GASTATNSESSTVSSGAS 418
Query: 2744 THEQSESSHGWTGPSTRGRQGS 2765
T SESS +G +T GS
Sbjct: 419 TATNSESSTTSSGANTATNSGS 440
Score = 79.0 bits (193), Expect = 9e-14
Identities = 119/496 (23%), Positives = 191/496 (38%), Gaps = 67/496 (13%)
Query: 355 QSGTRHAETSSRGQTASSHEQARSSPGERHGSGHQQSADS----SRHSATGRGQASSAVS 410
++ T ETS+ T SS + +S GS S S S S T G S +
Sbjct: 19 EAATNSNETSTSANTGSSVISSGASTATNSGSSVTSSGVSTATISGSSVTSNG-VSIVTN 77
Query: 411 DRGHRGSSG-SQASDSEGHSENSD----TQSVSGHGKAGLRQQSHQESTRGRSGERSGRS 465
H SSG S A++SE + +S T S S +G ++ ES+ SG + +
Sbjct: 78 SEFHTTSSGISTATNSEFSTVSSGISIATNSESSTTSSGASTATNSESSTPSSGASTATN 137
Query: 466 GSSLYQVSTHEQPDSAHGRTGTSTGGRQGSHHEQARDSSRHSASQEGQDTIRGHPGSSRG 525
S S+ T T++ S +S S + G T S+
Sbjct: 138 SDS--------STTSSGASTATNSDSSTTSSEASTATNSESSTTSSGASTATNSESSTVS 189
Query: 526 GRQGS--HHEQSVNRSGHSGSHHSH--TTSQGRSDASHGQSGSRSASRQTRNEEQSGDGT 581
R + + E S SG S + +S TTS G A++ +S + S+ T +S +
Sbjct: 190 SRASTATNSESSTTSSGASTATNSESRTTSNGAGTATNSESSTTSSGASTATNSESSTPS 249
Query: 582 RHSGSRHHEASSQADSSRHSQVGQGQSSGPRTSRN-QGSSVSQDSDSQGHSEDSERWSGS 640
+G+ + SS SSG T+ N + S+VS + +SE S SG+
Sbjct: 250 SGAGTATNSESSTT------------SSGAGTATNSESSTVSSGISTVTNSESSTPSSGA 297
Query: 641 ASRNHHGSAQEQSRDGSRHPRSHHEDRAGHGHSADSSRKSGTRHTQNSSSGQAASSHEQA 700
+ + S+ S G+ + G S ++ +S T +SSG + +++ ++
Sbjct: 298 NTATNSESSTTSS--GANTATNSDSSTTSSGASTATNSESST-----TSSGASTATNSES 350
Query: 701 RSSAGERHGSRHQLQSADSSRHSG--TGHGQASSAVRDSGHRGSSGSQATDSEGHSEDSD 758
+++ G+ S S+ SG T SS V ++ +T S G S +
Sbjct: 351 STTSS---GASTATNSGSSTTSSGTSTATNSESSTVSSGASTATTSESSTTSSGAS--TA 405
Query: 759 TQSVSGHGQAGHHQQSHQESARDRSGERSRRSGSFLYQVSTHKQSESSHGWTGPSTGVRQ 818
T S S +G ++ ES+ SG +T S SS G T
Sbjct: 406 TNSESSTVSSGASTATNSESSTTSSG------------ANTATNSGSSVTSAGSGTAALT 453
Query: 819 GSHHEQARDNSRHSAS 834
G H + HSAS
Sbjct: 454 GMH------TTSHSAS 463
Score = 79.0 bits (193), Expect = 9e-14
Identities = 113/472 (23%), Positives = 183/472 (38%), Gaps = 50/472 (10%)
Query: 3397 ESAHGRTRTSTGRRQGSHHEQARDSSRHSASQEGQDTIRGHPGSSRRGRQGSHYEQSVDR 3456
E+A TST GS S +A+ G G S GS SV
Sbjct: 19 EAATNSNETSTSANTGS---SVISSGASTATNSGSSVTSS--GVSTATISGS----SVTS 69
Query: 3457 SGHSGSHHS--HTTSQGRSDASRGQSGSRSASRQTRNDEQSGDGSRHSWSHHHEASTQAD 3514
+G S +S HTTS G S A+ + + S+ + +S S + +T ++
Sbjct: 70 NGVSIVTNSEFHTTSSGISTATNSEFSTVSSGISIATNSESSTTSSGA-----STATNSE 124
Query: 3515 SSRHSQSGQGQSAGPRTSRNQGSSVSQDSDSQ---------GHSEDSERWSGSASRNHRG 3565
SS S + ++ + G+S + +SDS +SE S SG+++ +
Sbjct: 125 SSTPSSGASTATNSDSSTTSSGASTATNSDSSTTSSEASTATNSESSTTSSGASTATNSE 184
Query: 3566 SAQEQSR-----DGSRHPTSHHEDRAGHGHSAESSRQSGT----HHAENSSGGQAASSHE 3616
S+ SR + TS A + S +S +GT + SSG A++ E
Sbjct: 185 SSTVSSRASTATNSESSTTSSGASTATNSESRTTSNGAGTATNSESSTTSSGASTATNSE 244
Query: 3617 QARSSAGERHGSHHQQSADSSRHSGIGHGQASSAVRDSGHRGSSGSQASDSEGHSEDSDT 3676
+ S+G ++ + S SS +G SS V ++ ++ S G + +++
Sbjct: 245 SSTPSSGAGTATNSESSTTSS-GAGTATNSESSTVSSGISTVTNSESSTPSSGANTATNS 303
Query: 3677 QSVSAHGQAGPHQQSHQEST-RGRSAGRSGRSGSFLYQVSTHEQSESAHGRAGPSTGGRQ 3735
+S + A S +T G S + S + ST SES+ +G ST
Sbjct: 304 ESSTTSSGANTATNSDSSTTSSGASTATNSESSTTSSGASTATNSESSTTSSGASTATNS 363
Query: 3736 GSRHEQARDSSRHSASQEGQDTIRGHPGSRRGGRQGSYHEQSVDRSGHSGSHHSH--TTS 3793
GS S +A+ T+ G + E S SG S + +S T S
Sbjct: 364 GS---STTSSGTSTATNSESSTVSS------GASTATTSESSTTSSGASTATNSESSTVS 414
Query: 3794 QGRSDASHGQSGSRSASRETRNEEQSGDGSRHSGSRHHEASTQADSSRHSQS 3845
G S A++ +S + S+ T S S SG+ A T ++ HS S
Sbjct: 415 SGASTATNSESSTTSSGANTATNSGSSVTSAGSGT---AALTGMHTTSHSAS 463
Score = 79.0 bits (193), Expect = 9e-14
Identities = 116/487 (23%), Positives = 179/487 (36%), Gaps = 60/487 (12%)
Query: 306 HSEDSERHSGSASRNHHGSAWEQSRDGSRHPRSHDEDRASHGHSADSSRQSGTRHAE--- 362
+S ++ + + S A + GS S G S S+ S ++E
Sbjct: 23 NSNETSTSANTGSSVISSGASTATNSGSSVTSSGVSTATISGSSVTSNGVSIVTNSEFHT 82
Query: 363 TSSRGQTASSHEQARSSPGERHGSGHQQSADSSRHSATGRGQASSAVSDRGHRGSSGSQA 422
TSS TA++ E + S G + + S SS G A+++ S G+S +
Sbjct: 83 TSSGISTATNSEFSTVSSGISIATNSESSTTSS-----GASTATNSESSTPSSGASTATN 137
Query: 423 SDSEGHSENSDTQSVSGHGKAGLRQQSHQESTRGRSGERSGRSGSSLYQVSTHEQPDSAH 482
SDS S + T + S S + ST S + SG+S +T+ + +
Sbjct: 138 SDSSTTSSGASTATNSDSSTT-----SSEASTATNSESSTTSSGAS---TATNSESSTVS 189
Query: 483 GRTGTSTGGRQGSHHEQARDSSRHSASQEGQDTIRGHPGSSRGGRQGSHHEQSVNRSGHS 542
R T+T +S S + G T S + N +G +
Sbjct: 190 SRASTAT-------------NSESSTTSSGAST-----------ATNSESRTTSNGAGTA 225
Query: 543 GSHHSHTTSQGRSDASHGQSGSRSASRQTRNEEQSGDGTRHSGSRHHEASSQADSSRHSQ 602
+ S TTS G S A++ +S + S+ T +S + +G+ + SS SS S
Sbjct: 226 TNSESSTTSSGASTATNSESSTPSSGAGTATNSESSTTSSGAGTATNSESSTV-SSGIST 284
Query: 603 VGQGQ----SSGPRTSRNQGSSVSQDSDSQGHSEDSERWSGSASRNHHGSAQEQSRDGSR 658
V + SSG T+ N SS + + + DS S AS + + S S
Sbjct: 285 VTNSESSTPSSGANTATNSESSTTSSGANTATNSDSSTTSSGASTATNSESSTTSSGAST 344
Query: 659 HPRSHHEDRAGHG----HSADSSRKSGTRHTQNSSSGQAASSHEQARSSAGERHGSRHQL 714
S + +S S+ SGT NS S +S A +S S
Sbjct: 345 ATNSESSTTSSGASTATNSGSSTTSSGTSTATNSESSTVSSGASTATTSESSTTSSG--- 401
Query: 715 QSADSSRHSGTGHGQASSAVRDSGHRGSSGSQATDSEGHSEDSDTQSVSGHGQA---GHH 771
S ++ S T AS+A SSG+ + G S S +G G A G H
Sbjct: 402 ASTATNSESSTVSSGASTATNSESSTTSSGANTATNSGSSVTS-----AGSGTAALTGMH 456
Query: 772 QQSHQES 778
SH S
Sbjct: 457 TTSHSAS 463
Score = 77.4 bits (189), Expect = 3e-13
Identities = 114/481 (23%), Positives = 186/481 (38%), Gaps = 45/481 (9%)
Query: 822 HEQARDNSRHSASQDGQDTIRGHPGSSRRGRQGSHHEQSVDRSGHSGS--HHSHTTSQGR 879
H +A NS +++ + G+S GS SV SG S + S TS G
Sbjct: 17 HLEAATNSNETSTSANTGSSVISSGASTATNSGS----SVTSSGVSTATISGSSVTSNGV 72
Query: 880 SDASRGQSGSRSAS-RTTRNEEQSRDGSRHSGSRHHEASSHADISRHSQAGQGQSEGSRT 938
S + + + S+ T N E S S S + + E+S+ + +G + S +
Sbjct: 73 SIVTNSEFHTTSSGISTATNSEFSTVSSGISIATNSESST-------TSSGASTATNSES 125
Query: 939 SR-RQGSSVSQDSDSEGHSEDSERWSGSASRNHRGSAQEQSRHGSRHPRSHHEDRAGHGH 997
S G+S + +SDS S + + S S A + S S
Sbjct: 126 STPSSGASTATNSDSSTTSSGASTATNSDSSTTSSEASTATNSESSTTSSGASTATNSES 185
Query: 998 SADSSRQSGTPHAE---TSSGGQAASSHEQARSSPGERHGSRHQQSADSSRHSGIPRRQA 1054
S SSR S ++E TSSG A++ E +S G + + S SS S ++
Sbjct: 186 STVSSRASTATNSESSTTSSGASTATNSESRTTSNGAGTATNSESSTTSSGASTATNSES 245
Query: 1055 SSAVRDSG-HWGSSGSQASDSEGHSEESDTQSVSGHGQDGPHQQSHQESARDWSGGRSGR 1113
S+ +G S S S G + S++ +VS G ++ ES+ SG
Sbjct: 246 STPSSGAGTATNSESSTTSSGAGTATNSESSTVS----SGISTVTNSESSTPSSG----- 296
Query: 1114 SGSFIYQVSTHEQSESAHGRTRTSTGRRQGSHHEQARDSSRHSASQEGQDTIRAHPGSRR 1173
+T SES + TS+G ++ + + SS S + + + + S
Sbjct: 297 -------ANTATNSES----STTSSGANTATNSDSSTTSSGASTATNSESSTTSSGASTA 345
Query: 1174 GGRQGSHHEQSVDRSGHSGSHHSHTTSQGRSDASHGQSGSRSASRQTRKDKQSGDGSRHS 1233
+ S + +SG S TTS G S A++ +S + S+ T +S S +
Sbjct: 346 TNSESSTTSSGASTATNSG---SSTTSSGTSTATNSESSTVSSGASTATTSESSTTSSGA 402
Query: 1234 GSRHHEAASWADSSRHSQVGQEQ---SSGSRTSRHQGSSVSQDSDSERHSDDSERLSGSA 1290
+ + +S S + E SSG+ T+ + GSSV+ S SA
Sbjct: 403 STATNSESSTVSSGASTATNSESSTTSSGANTATNSGSSVTSAGSGTAALTGMHTTSHSA 462
Query: 1291 S 1291
S
Sbjct: 463 S 463
Score = 77.4 bits (189), Expect = 3e-13
Identities = 112/475 (23%), Positives = 189/475 (39%), Gaps = 59/475 (12%)
Query: 2621 DSSRQSGTRHTQTSSGGQAASSHEQARSSAGERHGSHHQQSADSSRHSGIGHGQASSAVR 2680
+++ S T ++G SS +++G S +A S S +G S
Sbjct: 19 EAATNSNETSTSANTGSSVISSGASTATNSGSSVTSSGVSTATISGSSVTSNG-VSIVTN 77
Query: 2681 DSGHRGYSGSQASDNEGHSEDSDTQSVSAHGQAGSHQQSHQESARGRSGETSGHSGSFLY 2740
H SG + N S S S++ + ++ + ++ G S T+ S +
Sbjct: 78 SEFHTTSSGISTATNSEFSTVSSGISIATNSESST-------TSSGASTATNSESSTPSS 130
Query: 2741 QVSTHEQSESSHGWTGPSTRGRQGSRHEQAQDSSRHSASQDGQDTIRGHPGSSRGGRQGY 2800
ST S+SS +G ST + + + SS S + + + + +S G
Sbjct: 131 GASTATNSDSSTTSSGAST----ATNSDSSTTSSEASTATNSESST-----TSSGASTAT 181
Query: 2801 HHEHSVDSSGHSGSHHSH--TTSQGRSDASRGQSGSRS-ASRTTRNEEQSGDGSRHSGSR 2857
+ E S SS S + +S TTS G S A+ +S + S + T N E S S S +
Sbjct: 182 NSESSTVSSRASTATNSESSTTSSGASTATNSESRTTSNGAGTATNSESSTTSSGASTAT 241
Query: 2858 HHEASTH---ADISRHSQAVQGQSEGSRRSRRQGSSVSQDSDSEGHSEDSERWSGSASRN 2914
+ E+ST A + +S++ S + + S+VS + +SE S SG+ +
Sbjct: 242 NSESSTPSSGAGTATNSESSTTSSGAGTATNSESSTVSSGISTVTNSESSTPSSGANTAT 301
Query: 2915 HHGSAQEQLRDGSRHPRSHQEDRAGHGHSADSSRQSGTRHTQTSSGGQAASSHEQARSSA 2974
+ S S A ++DSS TSSG A++ E + +S+
Sbjct: 302 NSES-------------STTSSGANTATNSDSST--------TSSGASTATNSESSTTSS 340
Query: 2975 GERHGSHHQQSADSSRHSGIGHGQASSAVRDSGHRGYSGSQASDNEGHSEDSDTQSVSAH 3034
G ++ + S SS AS+A SG+ + N S++ +VS+
Sbjct: 341 GASTATNSESSTTSS--------GASTATNSGSSTTSSGTSTATN------SESSTVSSG 386
Query: 3035 GQAGSHQQSHQESARGRSGETSGHSGSFLYQVSTHEQSESSHGWTGPSTRGRQGS 3089
+ +S S+ G S T+ S + ST SESS +G +T GS
Sbjct: 387 ASTATTSESSTTSS-GASTATNSESSTVSSGASTATNSESSTTSSGANTATNSGS 440
Score = 77.4 bits (189), Expect = 3e-13
Identities = 97/388 (25%), Positives = 159/388 (40%), Gaps = 19/388 (4%)
Query: 267 SSSQVNRSRHENTSQVPLQESRTRKRRGSRVSQDRDSEGHSEDSERHSGSASRNHHGSAW 326
+SS ++ + + S V S S S + +SE S SG+++ + S+
Sbjct: 83 TSSGISTATNSEFSTVSSGISIATNSESSTTSSGASTATNSESSTPSSGASTATNSDSST 142
Query: 327 EQS--RDGSRHPRSHDEDRASHGHSADSSRQSGTRHAETSSRGQTASSHEQ-ARSSPGER 383
S + S AS +++SS S T+S T SS A +S
Sbjct: 143 TSSGASTATNSDSSTTSSEASTATNSESSTTSSGASTATNSESSTVSSRASTATNSESST 202
Query: 384 HGSGHQQSADS-SRHSATGRGQASSAVSDRGHRGSSGSQASDSEGHSENSD--TQSVSGH 440
SG + +S SR ++ G G A+++ S G+S + S+S S + T S S
Sbjct: 203 TSSGASTATNSESRTTSNGAGTATNSESSTTSSGASTATNSESSTPSSGAGTATNSESST 262
Query: 441 GKAGLRQQSHQESTRGRSGERSGRSGSSLYQVSTHEQPDSAHGRTGTSTGGRQGSHHEQA 500
+G ++ ES+ SG + + S S ++ T TS+G ++ + +
Sbjct: 263 TSSGAGTATNSESSTVSSGISTVTNSESSTPSSGANTATNSESST-TSSGANTATNSDSS 321
Query: 501 RDSSRHSASQEGQDTIRGHPGSSRGGRQGSHHEQSVNRSGHSGSHH--SHTTSQGRSDAS 558
SS S + + + +S G ++ E S SG S + + S TTS G S A+
Sbjct: 322 TTSSGASTATNSESST-----TSSGASTATNSESSTTSSGASTATNSGSSTTSSGTSTAT 376
Query: 559 HGQSG--SRSASRQTRNEEQ--SGDGTRHSGSRHHEASSQADSSRHSQVGQGQSSGPRTS 614
+ +S S AS T +E S + + S SS A ++ +S+ SSG T+
Sbjct: 377 NSESSTVSSGASTATTSESSTTSSGASTATNSESSTVSSGASTATNSE-SSTTSSGANTA 435
Query: 615 RNQGSSVSQDSDSQGHSEDSERWSGSAS 642
N GSSV+ S SAS
Sbjct: 436 TNSGSSVTSAGSGTAALTGMHTTSHSAS 463
Score = 75.5 bits (184), Expect = 1e-12
Identities = 94/433 (21%), Positives = 175/433 (40%), Gaps = 22/433 (5%)
Query: 1361 HQQSADSSRHSGIGHRQASSAVRDSGHRGS-SGSQVTNSEGHSEDSDTQSVSAHGQAGPH 1419
H ++A +S + SS + + SGS VT+S + SV+++G +
Sbjct: 17 HLEAATNSNETSTSANTGSSVISSGASTATNSGSSVTSSGVSTATISGSSVTSNGVSIVT 76
Query: 1420 QQSHKESARGQSGESSGRSRSFLYQVSSHEQSESTHGQTAPSTGGRQGSRHEQARNSSRH 1479
++ G S ++ + +S SES+ S+G + E + SS
Sbjct: 77 NSEFHTTSSGISTATNSEFSTVSSGISIATNSESS----TTSSGASTATNSESSTPSSGA 132
Query: 1480 SASQDGQDTIRGHPGSSRGGRQGSYHEQSVDRSGHSGYHHSHTTPQGRSDASHGQSGPRS 1539
S + + + S+ S + +S S TT G S A++ +S S
Sbjct: 133 STATNSDSSTTSSGASTATNSDSSTTSSEASTATNS---ESSTTSSGASTATNSESSTVS 189
Query: 1540 --ASRQTRNEEQ--SGDGSRHSGSRHHEPSTRAGSSRHSQVGQGESAGSKTSRRQGSSV- 1594
AS T +E S S + S S AG++ +S+ S+G+ T+ SS
Sbjct: 190 SRASTATNSESSTTSSGASTATNSESRTTSNGAGTATNSE-SSTTSSGASTATNSESSTP 248
Query: 1595 SQDRDSEGHSEDSERRSESASRNHYGSAREQSRHGSRNPRSHQEDRASHGHSAESSRQSG 1654
S + +SE S S + + + S+ S G + + S G + ++ +S
Sbjct: 249 SSGAGTATNSESSTTSSGAGTATNSESSTVSS--GISTVTNSESSTPSSGANTATNSESS 306
Query: 1655 TRHAETSSGGQAASSQEQARSSPGERHGSRHQQSADSSTDSGTGRRQDSSVVGDSGNRGS 1714
T TSSG A++ + + +S G + + +S+ +S+ + T +SS + +
Sbjct: 307 T----TSSGANTATNSDSSTTSSGASTAT-NSESSTTSSGASTATNSESSTTSSGASTAT 361
Query: 1715 SGSQASDSEGHSEESDTQSVSAHGQAGPHQQSHQEST-RGQSGERSGRSGSFLYQVSTHE 1773
+ ++ S G S ++++S + A S +T G S + S + ST
Sbjct: 362 NSGSSTTSSGTSTATNSESSTVSSGASTATTSESSTTSSGASTATNSESSTVSSGASTAT 421
Query: 1774 QSESAHGRTGPST 1786
SES+ +G +T
Sbjct: 422 NSESSTTSSGANT 434
Score = 75.5 bits (184), Expect = 1e-12
Identities = 104/479 (21%), Positives = 192/479 (40%), Gaps = 41/479 (8%)
Query: 3136 SGSHHSHTTSQGRSDASRGQSGSRSASRTTRNEEQSGDSSRHSVSRHHEASTHADISRHS 3195
+ ++ + T++ + +S SG+ +A+ + + SG S+ ++S S I +S
Sbjct: 20 AATNSNETSTSANTGSSVISSGASTATNSGSSVTSSGVSTA-TISGSSVTSNGVSIVTNS 78
Query: 3196 QAVQGQSEGSRRSRRQGSSVSQDSDSEGHSEDSERWSGSASRNHRGSVQEQSRHGSRHPR 3255
+ S S + + S+VS +SE S SG+++ + S S G+
Sbjct: 79 EFHTTSSGISTATNSEFSTVSSGISIATNSESSTTSSGASTATNSESSTPSS--GASTAT 136
Query: 3256 SHHEDRAGHGHSADRSRQSGTRHAETSSGGQAASSHEQARSSPGERHGSRHQQSADSSRH 3315
+ G S + S T TSS A++ E + +S G + + S SSR
Sbjct: 137 NSDSSTTSSGASTATNSDSST----TSSEASTATNSESSTTSSGASTATNSESSTVSSRA 192
Query: 3316 SGIPRGQASSAVRDSRHWGSSGSQASDSEGHSEESD----TQSVSGHGQAGPHQQSHQES 3371
S ++S+ S S A++SE + + T S S +G ++ ES
Sbjct: 193 STATNSESSTT-------SSGASTATNSESRTTSNGAGTATNSESSTTSSGASTATNSES 245
Query: 3372 ARDRSGGRSGRSGSFLYQVSTHEQSESAHGRTRTSTGRRQGSHHEQARDSSRHSASQEGQ 3431
+ SG T SES+ TS+G ++ E + SS S +
Sbjct: 246 STPSSGA------------GTATNSESS----TTSSGAGTATNSESSTVSSGISTVTNSE 289
Query: 3432 DTIRGHPGSSRRGRQGSHYEQSVDRSGHSGSHHSHTTSQGRSDASRGQSGSRSASRQT-R 3490
+ P S S + + + + S TTS G S A+ +S + S+ T
Sbjct: 290 SST---PSSGANTATNSESSTTSSGANTATNSDSSTTSSGASTATNSESSTTSSGASTAT 346
Query: 3491 NDEQSGDGSRHSWSHHHEASTQA---DSSRHSQSGQGQSAGPRTSRNQGSSVSQDSDSQG 3547
N E S S S + + +ST + ++ +S+S S + ++ S+ S + +
Sbjct: 347 NSESSTTSSGASTATNSGSSTTSSGTSTATNSESSTVSSGASTATTSESSTTSSGASTAT 406
Query: 3548 HSEDSERWSGSASRNHRGSAQEQSRDGSRHPTSHHEDRAGHGHSAESSRQSGTHHAENS 3606
+SE S SG+++ + S+ S + + AG G +A + + +H A +
Sbjct: 407 NSESSTVSSGASTATNSESSTTSSGANTATNSGSSVTSAGSGTAALTGMHTTSHSASTA 465
Score = 73.6 bits (179), Expect = 4e-12
Identities = 93/412 (22%), Positives = 166/412 (40%), Gaps = 32/412 (7%)
Query: 1136 TSTGRRQGSHHEQARDSSRHSASQEGQDTIRAHPGSRRGGRQGSHHEQSVDRSGHSGSHH 1195
TS+G ++ E + SS S + + + + G ++ E S SG S + +
Sbjct: 83 TSSGISTATNSEFSTVSSGISIATNSESSTTSS-----GASTATNSESSTPSSGASTATN 137
Query: 1196 SH--TTSQGRSDASHGQSGSRSASRQTRKDKQSGD----GSRHSGSRHHEAASWADSSRH 1249
S TTS G S A++ S + S+ T + +S S + S +S A ++ +
Sbjct: 138 SDSSTTSSGASTATNSDSSTTSSEASTATNSESSTTSSGASTATNSESSTVSSRASTATN 197
Query: 1250 SQVGQEQSSGSRTSRHQGSSVSQDSDSERHSDDSERLSGSASRNHHGSSREQSRDGSRHP 1309
S+ S S + + + S + + +S+ S SG+++ + SS S G+
Sbjct: 198 SESSTTSSGASTATNSESRTTSNGAGTATNSESSTTSSGASTATNSESSTPSSGAGT--- 254
Query: 1310 GFHQEDRASHGHSADSSRQSGTH-HTESSSHGQAVSSHEQARSSPGERHGSRHQQSADSS 1368
A++ S+ +S +GT ++ESS+ +S+ + SS + S S+
Sbjct: 255 -------ATNSESSTTSSGAGTATNSESSTVSSGISTVTNSESSTPSSGANTATNSESST 307
Query: 1369 RHSGIGHRQASSAVRDSGHRGSSGSQVTNSEGHSEDSD----TQSVSAHGQAGPHQQSHK 1424
SG S DS S S TNSE + S T S S+ +G ++
Sbjct: 308 TSSGANTATNS----DSSTTSSGASTATNSESSTTSSGASTATNSESSTTSSGASTATNS 363
Query: 1425 ESARGQSGESSGRSRSFLYQVSSHEQSESTHGQTAPSTGGRQGSRHEQARNSSRHSASQD 1484
S+ SG S+ + S VSS + +T + S+G + E + SS S + +
Sbjct: 364 GSSTTSSGTSTA-TNSESSTVSSGASTATTSESSTTSSGASTATNSESSTVSSGASTATN 422
Query: 1485 GQDTIRGHPGSSRGGRQGSYHEQSVDRSGHSGYH-HSHTTPQGRSDASHGQS 1535
+ + ++ S + +G H SH+ S+A G S
Sbjct: 423 SESSTTSSGANTATNSGSSVTSAGSGTAALTGMHTTSHSASTAVSEAKPGGS 474
Score = 72.4 bits (176), Expect = 9e-12
Identities = 116/508 (22%), Positives = 193/508 (37%), Gaps = 59/508 (11%)
Query: 2982 HQQSADSSRHSGIGHGQASSAVRDSGHRGYSGSQASDNEGHSEDSDTQSVSAHGQAGSHQ 3041
H ++A +S + SS + SG+ + N G S S VS +GS
Sbjct: 17 HLEAATNSNETSTSANTGSSVIS-------SGASTATNSGSSVTSS--GVSTATISGSSV 67
Query: 3042 QSHQESARGRSGETSGHSGSFLYQVSTHEQSESSHGWTGPSTRGRQGSRHEQAQDSSRHS 3101
S+ S S + SG +ST SE S +G S +S S
Sbjct: 68 TSNGVSIVTNSEFHTTSSG-----ISTATNSEFSTVSSGISIA-----------TNSESS 111
Query: 3102 ASQYGQDTIRGHPGS--SRGGRQGYHHEHSVDSSGHSGSHHSH--TTSQGRSDASRGQSG 3157
+ G T S S G + + S SSG S + +S TTS S A+ +S
Sbjct: 112 TTSSGASTATNSESSTPSSGASTATNSDSSTTSSGASTATNSDSSTTSSEASTATNSESS 171
Query: 3158 SRSASRTTR-NEEQSGDSSRHSVSRHHEAST---HADISRHSQAVQGQSEGSRRSRRQGS 3213
+ S+ +T N E S SSR S + + E+ST A + +S++ + + + S
Sbjct: 172 TTSSGASTATNSESSTVSSRASTATNSESSTTSSGASTATNSESRTTSNGAGTATNSESS 231
Query: 3214 SVSQDSDSEGHSEDSERWSGSASRNHRGSVQEQSRHGSRHPRSHHEDRAGHGHSADRSRQ 3273
+ S + + +SE S SG+ + + S S G+ + G S + +
Sbjct: 232 TTSSGASTATNSESSTPSSGAGTATNSESSTTSS--GAGTATNSESSTVSSGISTVTNSE 289
Query: 3274 SGTRHAETSSGGQAASSHEQARSSPGERHGSRHQQSADSSRHSGIPRGQASSAVRDSRHW 3333
S T SSG A++ E + +S G + S SS G +++ +S
Sbjct: 290 SST----PSSGANTATNSESSTTSSGANTATNSDSSTTSS-------GASTATNSESSTT 338
Query: 3334 GSSGSQASDSEGHSEESDTQSVSGHGQAGPHQQSHQESARDRSGGRSGRSGSFLYQVSTH 3393
S S A++SE + S + + G + S G S + S VS+
Sbjct: 339 SSGASTATNSESSTTSSGASTATNSGSS------------TTSSGTSTATNSESSTVSSG 386
Query: 3394 EQSESAHGRTRTSTGRRQGSHHEQARDSSRHSASQEGQDTIRGHPGSSRRGRQGSHYEQS 3453
+ + + TS+G ++ E + SS S + + + ++ S
Sbjct: 387 ASTATTSESSTTSSGASTATNSESSTVSSGASTATNSESSTTSSGANTATNSGSSVTSAG 446
Query: 3454 VDRSGHSGSH-HSHTTSQGRSDASRGQS 3480
+ +G H SH+ S S+A G S
Sbjct: 447 SGTAALTGMHTTSHSASTAVSEAKPGGS 474
Score = 72.0 bits (175), Expect = 1e-11
Identities = 100/466 (21%), Positives = 175/466 (37%), Gaps = 26/466 (5%)
Query: 1128 ESAHGRTRTSTGRRQGSHHEQARDSSRHSASQEGQDTIRAHPGSRRGGRQGSHHEQSVDR 1187
E+A TST GS S +A+ G + G + SV
Sbjct: 19 EAATNSNETSTSANTGS---SVISSGASTATNSGSSVTSS------GVSTATISGSSVTS 69
Query: 1188 SGHSGSHHS--HTTSQGRSDASHGQSGSRSASRQTRKDKQSGDGSRHSGSRHHEAASWAD 1245
+G S +S HTTS G S A++ + + S+ + +S S + + + +S
Sbjct: 70 NGVSIVTNSEFHTTSSGISTATNSEFSTVSSGISIATNSESSTTSSGASTATNSESSTPS 129
Query: 1246 SSRHSQVGQEQSSGSRTSRHQGSSVSQDSDSERHSDDSERLSGSASRNHHGSSREQSRDG 1305
S + + S+ S G+S + +SDS S ++ + S S + +
Sbjct: 130 SGASTATNSDSSTTS-----SGASTATNSDSSTTSSEASTATNSESSTTSSGASTATNSE 184
Query: 1306 SRHPGFHQEDRASHGHSADSSRQSGTHHTESSSHGQAVSSHEQARSSPGERHGSRHQQSA 1365
S + S SS S ++ES + + + SS S S
Sbjct: 185 SSTVSSRASTATNSESSTTSSGASTATNSESRTTSNGAGTATNSESSTTSSGASTATNSE 244
Query: 1366 DSSRHSGIGHRQASSAVRDSGHRGSSGSQVTNSEGHSEDSDTQSVSAHGQAGPHQQSHKE 1425
S+ SG G S + S G++ + +++ + T S S+ +G + ++ E
Sbjct: 245 SSTPSSGAGTATNSESSTTSSGAGTATNSESSTVSSGISTVTNSESSTPSSGANTATNSE 304
Query: 1426 SARGQSGESSGRSRSFLYQVSSHEQSESTHGQTAPSTGGRQGSRHEQARNSSRHSASQDG 1485
S+ SG ++ + S SS + + + S+G + E + SS S +
Sbjct: 305 SSTTSSGANTA-TNSDSSTTSSGASTATNSESSTTSSGASTATNSESSTTSSGASTA--- 360
Query: 1486 QDTIRGHPGSSRGGRQGSYHEQSVDRSGHS--GYHHSHTTPQGRSDASHGQSGPRS--AS 1541
T G +S G + E S SG S S TT G S A++ +S S AS
Sbjct: 361 --TNSGSSTTSSGTSTATNSESSTVSSGASTATTSESSTTSSGASTATNSESSTVSSGAS 418
Query: 1542 RQTRNEEQSGDGSRHSGSRHHEPSTRAGSSRHSQVGQGESAGSKTS 1587
T +E + ++ + T AGS + G ++ S ++
Sbjct: 419 TATNSESSTTSSGANTATNSGSSVTSAGSGTAALTGMHTTSHSAST 464
Score = 71.2 bits (173), Expect = 2e-11
Identities = 125/539 (23%), Positives = 198/539 (36%), Gaps = 88/539 (16%)
Query: 2024 HGQASSAVRDSGHRGYSGSQASDSEGHSEDSDTQSVSAQGKAGPHQQSHKESARGQSGES 2083
H +A++ ++ +GS S + + SV++ G + + G S S
Sbjct: 17 HLEAATNSNETSTSANTGSSVISSGASTATNSGSSVTSSGVS-------TATISGSSVTS 69
Query: 2084 SGRSGSFLYQVSTHEQSESTHGQSAPSTGGRQGSHYDQAQDSSRHSASQEGQDTIRGHPG 2143
+G S + T+ + +T + +T S + + + E T
Sbjct: 70 NGVS------IVTNSEFHTTSSGISTATN----SEFSTVSSGISIATNSESSTT------ 113
Query: 2144 PSRGGRQGSHQEQSVDRSGHSGSHHSH--TTSQGRSDASRGQSGSRSASRKTYDKEQSGD 2201
S G ++ E S SG S + +S TTS G S A+ S + S+ T +S
Sbjct: 114 -SSGASTATNSESSTPSSGASTATNSDSSTTSSGASTATNSDSSTTSSEASTATNSESST 172
Query: 2202 GSRHSGSHHHEASSWADSSRHSLVGQGQSSGPRTSRPRGSSVSQDSDSEGHSEDSERRSG 2261
S + + + SS SSR S +SS + G+S + +S+S S + +
Sbjct: 173 TSSGASTATNSESSTV-SSRASTATNSESS----TTSSGASTATNSESRTTSNGAGTATN 227
Query: 2262 SASRNHHGSAQEQSRDGSRHPRSHHEDRAGHGHSAESSRQSGTHHAENSSGGQAASSHEQ 2321
S S A + S P S AG ++ESS SSG A++ E
Sbjct: 228 SESSTTSSGASTATNSESSTPSSG----AGTATNSESST--------TSSGAGTATNSES 275
Query: 2322 ARSSAGERHGSHHQQSADSSRHSGIGHGQASSAVRDSGHRGSSGSQASDSEGHSEDSDTQ 2381
+ S+G ++ + S SS A++A SSG+ + + DS T
Sbjct: 276 STVSSGISTVTNSESSTPSS--------GANTATNSESSTTSSGANTAT----NSDSSTT 323
Query: 2382 SVSAHGQAGPHQQSHQESTRGRSAGRSGRSGSFLYQVSTHEQSESAHGRTGTSTGGRQGS 2441
S A ST S + SG+ ST SES+ +G ST GS
Sbjct: 324 SSGA-------------STATNSESSTTSSGA-----STATNSESSTTSSGASTATNSGS 365
Query: 2442 HHKQARDSSRHSTSQEGQDTIHGHPGS--SSGGRQGSHYEQLVDRSGHSGSHHSH--TTS 2497
ST+ G T S SSG + E SG S + +S T S
Sbjct: 366 -----------STTSSGTSTATNSESSTVSSGASTATTSESSTTSSGASTATNSESSTVS 414
Query: 2498 QGRSDASHGHSGSRSASRQTRNDEQSGDGSRHSGSRHHEASSRADSSGHSQVGQGQSEG 2556
G S A++ S + S+ T + S S SG+ S + V + + G
Sbjct: 415 SGASTATNSESSTTSSGANTATNSGSSVTSAGSGTAALTGMHTTSHSASTAVSEAKPGG 473
Score = 63.9 bits (154), Expect = 3e-09
Identities = 84/364 (23%), Positives = 141/364 (38%), Gaps = 38/364 (10%)
Query: 260 SRSSDGKSSSQVNRSRHENTSQVPLQESRTRKRRGSRVSQDRDSEGHSEDSERHSGSASR 319
+ S SS + + + ++S S S S + + +SE S SG+++
Sbjct: 121 TNSESSTPSSGASTATNSDSSTTSSGASTATNSDSSTTSSEASTATNSESSTTSSGASTA 180
Query: 320 NHHGSAWEQSR-----DGSRHPRSHDEDRASHGHSADSSRQSGT----RHAETSSRGQTA 370
+ S+ SR + S A++ S +S +GT + TSS TA
Sbjct: 181 TNSESSTVSSRASTATNSESSTTSSGASTATNSESRTTSNGAGTATNSESSTTSSGASTA 240
Query: 371 SSHEQARSSPGERHGSGHQQSADSSRHSATGRGQASSAVSDRGHRGSSGSQASDSEGHSE 430
++ E + S G + + S SS G G A+++ S G S S+S S
Sbjct: 241 TNSESSTPSSGAGTATNSESSTTSS-----GAGTATNSESSTVSSGISTVTNSESSTPSS 295
Query: 431 --NSDTQSVSGHGKAGLRQQSHQESTRGRSGERSG---RSGSSLYQVSTHEQPDSAHGRT 485
N+ T S S +G ++ +S+ SG + S ++ ST +S+ +
Sbjct: 296 GANTATNSESSTTSSGANTATNSDSSTTSSGASTATNSESSTTSSGASTATNSESSTTSS 355
Query: 486 GTSTGGRQGSHHEQARDSSRHSASQEGQDTIRGHPGSSRGGRQGSHHEQSVNRSGHSGSH 545
G ST GS S +A+ T+ S G + E S SG S +
Sbjct: 356 GASTATNSGS---STTSSGTSTATNSESSTV------SSGASTATTSESSTTSSGASTAT 406
Query: 546 HSH--TTSQG-----RSDASHGQSGSRSASRQTRNEEQSGDGTRHSGSRH---HEASSQA 595
+S T S G S++S SG+ +A+ + +G GT H H AS+
Sbjct: 407 NSESSTVSSGASTATNSESSTTSSGANTATNSGSSVTSAGSGTAALTGMHTTSHSASTAV 466
Query: 596 DSSR 599
++
Sbjct: 467 SEAK 470
>gi|56606114 trichohyalin-like 1 [Homo sapiens]
Length = 904
Score = 90.5 bits (223), Expect = 3e-17
Identities = 147/689 (21%), Positives = 248/689 (35%), Gaps = 70/689 (10%)
Query: 1 MSTLLENIFAIINLFKQYSKKDKNTDTLSKKELKELLEKEFRQILKNPDDPDMVDVFMDH 60
M LL N+ +I F +Y+ +D N TL+ +ELK+L++ EF + P V+ +
Sbjct: 1 MPQLLRNVLCVIETFHKYASEDSNGATLTGRELKQLIQGEFGDFFQ-PCVLHAVEKNSNL 59
Query: 61 LDIDHNKKIDFTEFLLMVFKLAQAYYESTRKENLPISGHKHRKHSHHDKHED-NKQEENK 119
L+ID N I F EF+L +F L Y + +L S + +K +D + Q
Sbjct: 60 LNIDSNGIISFDEFVLAIFNLLNLCYLDIK--SLLSSELRQVTKPEKEKLDDVDVQATTG 117
Query: 120 ENRKRPSSLERRNNRKGNKGRSKS----PRETGGKRHESSSEKKERKGYSPTHREEEYGK 175
+ + + + R G + S P E+G + +E K TH
Sbjct: 118 DGQWTVGTSPTQEKRMLPSGMASSSQLIPEESGAVGNNRVDPWREAK----THNFPGEAS 173
Query: 176 NHHNSSKKEKNKTENTRLGDNRKRLSERLEEKEDNE------EGVYDYENTGRMTQKWIQ 229
H++ K E + + +++ ++ EDNE + + + T T++ Q
Sbjct: 174 EHNDPKNKHLEGDEQS------QEVAQDIQTTEDNEGQLKTNKPMAGSKKTSSPTERKGQ 227
Query: 230 SGHIATYYTIQDEAYDTTDSLLEENKIYERSRSSDGKSSSQVNRSRHENTSQVPLQESRT 289
I+ + D +KI ++ +G ++Q + + QE RT
Sbjct: 228 DKEIS-------QEGDEPAREQSVSKIRDQFGEQEGNLATQSSPPKEATQRPCEDQEVRT 280
Query: 290 RKRRGSRVSQ---DRDSEGHSEDSERHSGSASRNHHGSAWEQSRDGSRHPRSHDEDRASH 346
K + S + + R+ E S+ ++ +A+R+ S ++S D R D
Sbjct: 281 EKEKHSNIQEPPLQREDEPSSQHADLPEQAAARS--PSQTQKSTDSKDVCRMFDTQEP-- 336
Query: 347 GHSADSSRQSGTRHAETSSRGQTASSHE---QARSSP---GERHGSGHQQSAD--SSRHS 398
G AD + E G+T+ + E + + P G R+GS D R
Sbjct: 337 GKDADQTPAKTKNLGEPEDYGRTSETQEKECETKDLPVQYGSRNGSETSDMRDERKERRG 396
Query: 399 ATGRGQASSAVSDRGHRG------------SSGSQASDSEGHSENSDTQSVSGHGKAGLR 446
G A DR R S S+ + S+TQ +S G
Sbjct: 397 PEAHGTAGQKERDRKTRPLVLETQTQDGKYQELQGLSKSKDAEKGSETQYLSSEGGDQTH 456
Query: 447 QQSHQESTRGRSGERSGRSGSSLYQVSTH----EQPDSAHGRTGTSTGGRQGSHHEQARD 502
+ + G E + + + S + E+ A RT + S E R
Sbjct: 457 PELEGTAVSGEEAEHTKEGTAEAFVNSKNAPAAERTLGARERTQDLAPLEKQSVGENTRV 516
Query: 503 SSRHSASQEGQDTIRGHPGSSRGGRQGSHHEQSVN----RSGHSGSHHSHTTSQGRSDAS 558
+ H E +D +G S + ++ N G+S S QG S +
Sbjct: 517 TKTHDQPVEEEDGYQGEDPESPFTQSDEGSSETPNSLASEEGNSSSETGELPVQGDSQSQ 576
Query: 559 HGQSGSRSASRQTRNEEQSGDGTRHSGSRHHEASSQADSSRHSQVGQGQSSGPR-TSRNQ 617
Q G N + GT +R EA A Q+ + Q R +NQ
Sbjct: 577 GDQHGESVQGGHNNNPDTQRQGTPGEKNRALEAVVPAVRGEDVQLTEDQEQPARGEHKNQ 636
Query: 618 GSSVSQDS---DSQGHSEDSERWSGSASR 643
G + GH E E +G +R
Sbjct: 637 GPGTKGPGAAVEPNGHPEAQESTAGDENR 665
Score = 66.2 bits (160), Expect = 6e-10
Identities = 133/679 (19%), Positives = 239/679 (35%), Gaps = 114/679 (16%)
Query: 3158 SRSASRTTRNEEQSGDSSRHSVSRHHEASTH---ADISRHSQAVQGQSEGSRRSRRQGSS 3214
S AS + E+SG + V EA TH + S H+ EG +S+
Sbjct: 136 SGMASSSQLIPEESGAVGNNRVDPWREAKTHNFPGEASEHNDPKNKHLEGDEQSQEVAQD 195
Query: 3215 VSQDSDSEGHSEDSERWSGSASRN----HRGSVQEQSRHGSRHPR----SHHEDRAGH-- 3264
+ D+EG + ++ +GS + +G +E S+ G R S D+ G
Sbjct: 196 IQTTEDNEGQLKTNKPMAGSKKTSSPTERKGQDKEISQEGDEPAREQSVSKIRDQFGEQE 255
Query: 3265 GHSADRS---RQSGTRHAETSSGGQAASSHEQARSSPGERHGSRHQQSADSSRHSGIPRG 3321
G+ A +S +++ R E H + P +R + SS+H+ +P
Sbjct: 256 GNLATQSSPPKEATQRPCEDQEVRTEKEKHSNIQEPPLQR------EDEPSSQHADLPEQ 309
Query: 3322 QASSAVRDSRHWGSSGSQASDSEGHSEESDTQSVSGHGQAGPHQQSHQESARDRSGGRSG 3381
A+ + S +++DS+ DTQ P + + Q A+ ++ G
Sbjct: 310 AAARSP-------SQTQKSTDSKDVCRMFDTQE--------PGKDADQTPAKTKNLGEPE 354
Query: 3382 RSGSFLYQVSTHEQSESAHGRTRTSTGRRQGSHHEQARDSSRHSASQEGQDTIRGHPGSS 3441
G + S ++ E G R GS RD + E T G
Sbjct: 355 DYG----RTSETQEKECETKDLPVQYGSRNGSETSDMRDERKERRGPEAHGTA-GQKERD 409
Query: 3442 RRGR--------QGSHYEQ----SVDRSGHSGSHHSHTTSQGRSDASRGQSGSRSASRQT 3489
R+ R Q Y++ S + GS + +S+G G+ + +
Sbjct: 410 RKTRPLVLETQTQDGKYQELQGLSKSKDAEKGSETQYLSSEGGDQTHPELEGTAVSGEEA 469
Query: 3490 RNDEQSGDGSRHSWSHHHEASTQADSSRHSQSGQGQSAGPRTSRNQGSSVSQDSDSQGHS 3549
E + +G+ ++ + A + + Q + + S + + V++ D
Sbjct: 470 ---EHTKEGTAEAFVNSKNAPAAERTLGARERTQDLAPLEKQSVGENTRVTKTHDQPVEE 526
Query: 3550 EDSERWSGSAS---RNHRGSAQEQSRDGSRHPTSHHEDRAGHGHSAESSRQSGTHHAENS 3606
ED + S ++ GS++ + S S E G S+ G H E+
Sbjct: 527 EDGYQGEDPESPFTQSDEGSSETPNSLASEEGNSSSE--TGELPVQGDSQSQGDQHGESV 584
Query: 3607 SGGQAASSHEQARSSAGERHGS------------------HHQQSADSSRHSGIGHGQAS 3648
GG + Q + + GE++ + Q + ++ G G
Sbjct: 585 QGGHNNNPDTQRQGTPGEKNRALEAVVPAVRGEDVQLTEDQEQPARGEHKNQGPGTKGPG 644
Query: 3649 SAVRDSGHRGSSGSQASDSE---------GHSEDSDTQSVSAHGQAGPHQQSHQESTRGR 3699
+AV +GH + S A D G ++ T +S G ++ +G
Sbjct: 645 AAVEPNGHPEAQESTAGDENRKSLEIEITGALDEDFTDQLSLMQLPGKGDSRNELKVQGP 704
Query: 3700 SA----GRSGRSGSFLYQ-------------------VSTHEQSESAHGRAGPSTGGRQG 3736
S+ GR+ + + L + V++ E+ ES AG GG Q
Sbjct: 705 SSKEEKGRATEAQNTLLESLDEDNSASLKIQLETKEPVTSEEEDESPQELAG--EGGDQK 762
Query: 3737 SRHEQARDSSRHSASQEGQ 3755
S ++ +SS +S E Q
Sbjct: 763 SPAKKEHNSSVPWSSLEKQ 781
Score = 65.9 bits (159), Expect = 8e-10
Identities = 113/601 (18%), Positives = 194/601 (32%), Gaps = 67/601 (11%)
Query: 2448 DSSRHSTSQEGQDTIHGHPGSSSG---GRQGSHYEQLVDRSGHSGSHHSHTTSQGRSDAS 2504
D +T+ +GQ T+ P S + + + SG G++ R +
Sbjct: 109 DVDVQATTGDGQWTVGTSPTQEKRMLPSGMASSSQLIPEESGAVGNNR---VDPWREAKT 165
Query: 2505 HGHSGSRSASRQTRNDEQSGDGSRHSGSRHHEASSRADSSGHSQVGQGQSEGPRTSRNWG 2564
H G S +N GD S + + D+ G + + + +TS
Sbjct: 166 HNFPGEASEHNDPKNKHLEGD--EQSQEVAQDIQTTEDNEGQLKTNKPMAGSKKTSSPTE 223
Query: 2565 SSFSQDSDSQGHSEDSERWSGSASRNHHGSAQEQLRDGSRHPR-SHQEDRAGHGHSADSS 2623
SQ E + S S R+ G + L S P+ + Q +
Sbjct: 224 RKGQDKEISQEGDEPAREQSVSKIRDQFGEQEGNLATQSSPPKEATQRPCEDQEVRTEKE 283
Query: 2624 RQSGTRHTQTSSGGQAASSHEQARSSAGERHGSHHQQSADS--------SRHSGIGHGQA 2675
+ S + + +S H A R S Q+S DS ++ G Q
Sbjct: 284 KHSNIQEPPLQREDEPSSQHADLPEQAAARSPSQTQKSTDSKDVCRMFDTQEPGKDADQT 343
Query: 2676 SSAVRDSGHRGYSG--SQASDNEGHSEDSDTQSVSAHGQAGSHQQSHQESARGRSGETSG 2733
+ ++ G G S+ + E ++D Q S +G S + ++ RG
Sbjct: 344 PAKTKNLGEPEDYGRTSETQEKECETKDLPVQYGSRNGSETSDMRDERKERRG------- 396
Query: 2734 HSGSFLYQVSTHEQSESSHGWTGPSTRGR-----------QGSRHEQAQDSSRHSASQDG 2782
+HG G R R Q ++++ Q S+ ++ G
Sbjct: 397 ---------------PEAHGTAGQKERDRKTRPLVLETQTQDGKYQELQGLSKSKDAEKG 441
Query: 2783 QDTIRGHPGSSRGGRQGYHHEHSVDSSGHSGSHHSHTTSQGRSDASRGQSGSRSASRTTR 2842
+T SS GG Q + SG H T++ ++ + R+ R
Sbjct: 442 SET---QYLSSEGGDQTHPELEGTAVSGEEAEHTKEGTAEAFVNSKNAPAAERTLGARER 498
Query: 2843 NEEQSGDGSRHSGSRHHEASTHADISRHSQAVQGQSEGSRRSRRQGSSVSQDSDSEGHSE 2902
++ + + G TH QG+ S + Q S ++ + SE
Sbjct: 499 TQDLAPLEKQSVGENTRVTKTHDQPVEEEDGYQGEDPESPFT--QSDEGSSETPNSLASE 556
Query: 2903 DSERWSGSASRNHHGSAQEQLRDGSRHPRSHQEDRAGHGHSADSSRQSGTRHTQTSSGGQ 2962
+ S + G +Q Q G +H S Q GH ++ D+ RQ T
Sbjct: 557 EGNSSSETGELPVQGDSQSQ---GDQHGESVQ---GGHNNNPDTQRQG----TPGEKNRA 606
Query: 2963 AASSHEQARSSAGERHGSHHQQSADSSRHSGIGHGQASSAVRDSGHRGYSGSQASDNEGH 3022
+ R + Q + ++ G G +AV +GH S A D
Sbjct: 607 LEAVVPAVRGEDVQLTEDQEQPARGEHKNQGPGTKGPGAAVEPNGHPEAQESTAGDENRK 666
Query: 3023 S 3023
S
Sbjct: 667 S 667
Score = 60.5 bits (145), Expect = 3e-08
Identities = 110/614 (17%), Positives = 207/614 (33%), Gaps = 80/614 (13%)
Query: 498 EQARDSSRHSASQEGQDTIRGHPGSSRGGRQGSHHEQSVNRSGHSGSHHSHTTSQGRSDA 557
E+ D + + +GQ T+ P + S SG+ ++ R
Sbjct: 105 EKLDDVDVQATTGDGQWTVGTSPTQEKRMLPSGMASSSQLIPEESGAVGNNRVDPWREAK 164
Query: 558 SHGQSGSRSASRQTRNEEQSGDGTRHSGSRHHEASSQADS---SRHSQVGQGQSSGPRTS 614
+H G S +N+ GD ++ + + + + G ++S P
Sbjct: 165 THNFPGEASEHNDPKNKHLEGDEQSQEVAQDIQTTEDNEGQLKTNKPMAGSKKTSSPTER 224
Query: 615 RNQGSSVSQDSDSQGHSEDSERWSGSASRNHHGSAQEQS--RDGSRHPRSHHEDRAGHGH 672
+ Q +SQ+ D + + A + S ++ ++ P E R
Sbjct: 225 KGQDKEISQEGDEPAREQSVSKIRDQFGEQEGNLATQSSPPKEATQRPCEDQEVRT---- 280
Query: 673 SADSSRKSGTRHTQNSSSGQAASSHEQARSSAGERHGSRHQLQSADS--------SRHSG 724
+ + S + + +S H A R S+ Q +S DS ++ G
Sbjct: 281 --EKEKHSNIQEPPLQREDEPSSQHADLPEQAAARSPSQTQ-KSTDSKDVCRMFDTQEPG 337
Query: 725 TGHGQASSAVRDSGHRGSSGSQATDSEGHSEDSDTQSVSGHGQAGHHQQSHQESARDRSG 784
Q + ++ G G + E E D Q G S RD
Sbjct: 338 KDADQTPAKTKNLGEPEDYGRTSETQEKECETKDLPV-----QYGSRNGSETSDMRD--- 389
Query: 785 ERSRRSGSFLYQVSTHKQSESSHGWTGPSTGVRQGSHHEQARDNSRHSASQDGQDTIRGH 844
ER R G + + K+ + T + G + E + S+ ++ G +T
Sbjct: 390 ERKERRGPEAHGTAGQKERDRKTRPLVLETQTQDGKYQE-LQGLSKSKDAEKGSET---- 444
Query: 845 PGSSRRGRQGSHHEQSVDRSGHSGSHHSHTTSQGRSDASRGQSGSRSASRTTRNEEQSRD 904
S G +H E ++ + SG HT +G ++A + +A RT E+++D
Sbjct: 445 QYLSSEGGDQTHPE--LEGTAVSGEEAEHT-KEGTAEAFVNSKNAPAAERTLGARERTQD 501
Query: 905 GSRHSGSRHHEASSHADISRHSQAGQGQSEGSRTSRRQGSSVSQDSDSEGHSEDSERWSG 964
A + + Q E +R ++ V ++ +G +S
Sbjct: 502 --------------LAPLEK-----QSVGENTRVTKTHDQPVEEEDGYQGEDPESP---- 538
Query: 965 SASRNHRGSAQEQSRHGSRHPRSHHEDRAGHGHSADSSRQSGTPHAETSSGGQAASSHEQ 1024
+++ GS++ + S S E G S+ G H E+ GG + Q
Sbjct: 539 -FTQSDEGSSETPNSLASEEGNSSSE--TGELPVQGDSQSQGDQHGESVQGGHNNNPDTQ 595
Query: 1025 ARSSPGERHGS------------------RHQQSADSSRHSGIPRRQASSAVRDSGHWGS 1066
+ +PGE++ + + Q + ++ G + +AV +GH +
Sbjct: 596 RQGTPGEKNRALEAVVPAVRGEDVQLTEDQEQPARGEHKNQGPGTKGPGAAVEPNGHPEA 655
Query: 1067 SGSQASDSEGHSEE 1080
S A D S E
Sbjct: 656 QESTAGDENRKSLE 669
Score = 58.9 bits (141), Expect = 1e-07
Identities = 93/502 (18%), Positives = 182/502 (36%), Gaps = 66/502 (13%)
Query: 2834 SRSASRTTRNEEQSGDGSRHSGSRHHEASTH---ADISRHSQAVQGQSEGSRRSRRQGSS 2890
S AS + E+SG + EA TH + S H+ EG +S+
Sbjct: 136 SGMASSSQLIPEESGAVGNNRVDPWREAKTHNFPGEASEHNDPKNKHLEGDEQSQEVAQD 195
Query: 2891 VSQDSDSEGHSEDSERWSGSASRNHHGSAQEQLRDGSRHPRSHQEDRAGHGHSADSSRQS 2950
+ D+EG + ++ +GS + + Q ++ S+ +++ Q
Sbjct: 196 IQTTEDNEGQLKTNKPMAGSKKTSSPTERKGQDKEISQEGDEPAREQSVSKIRDQFGEQE 255
Query: 2951 GTRHTQTSSGGQAASS--HEQARSSAGERHGSHHQ-----QSADSSRHSGIGHGQASSAV 3003
G TQ+S +A +Q + E+H + + + SS+H+ + A+ +
Sbjct: 256 GNLATQSSPPKEATQRPCEDQEVRTEKEKHSNIQEPPLQREDEPSSQHADLPEQAAARSP 315
Query: 3004 RDSGHRGYSGS--QASDNEGHSEDSD-----TQSVSAHGQAGSHQQSHQESARGRS---- 3052
+ S + D + +D+D T+++ G ++ ++ +
Sbjct: 316 SQTQKSTDSKDVCRMFDTQEPGKDADQTPAKTKNLGEPEDYGRTSETQEKECETKDLPVQ 375
Query: 3053 -GETSGHSGSFLYQVSTHEQSESSHGWTGPSTRGR-----------QGSRHEQAQDSSRH 3100
G +G S + + +HG G R R Q ++++ Q S+
Sbjct: 376 YGSRNGSETSDMRDERKERRGPEAHGTAGQKERDRKTRPLVLETQTQDGKYQELQGLSKS 435
Query: 3101 SASQYGQDTIRGHPGSSRGGRQGYHHEHSVDSSGHSGSHHSHTTSQGRSDASRGQSGSRS 3160
++ G +T SS GG Q + SG H T +G ++A + +
Sbjct: 436 KDAEKGSET---QYLSSEGGDQTHPELEGTAVSGEEAEH----TKEGTAEAFVNSKNAPA 488
Query: 3161 ASRTTRNEEQSGDSSRHSVSRHHEASTHADISRHSQAVQGQSEGSRRSRRQGSSVSQDSD 3220
A RT E++ D A + + Q E +R ++ V ++
Sbjct: 489 AERTLGARERTQDL--------------APLEK-----QSVGENTRVTKTHDQPVEEEDG 529
Query: 3221 SEGHSEDSERWSGSASRNHRGSVQEQSRHGSRHPRSHHEDRAGHGHSADRSRQSGTRHAE 3280
+G +S +++ GS + + S S E G S+ G +H E
Sbjct: 530 YQGEDPESP-----FTQSDEGSSETPNSLASEEGNSSSE--TGELPVQGDSQSQGDQHGE 582
Query: 3281 TSSGGQAASSHEQARSSPGERH 3302
+ GG + Q + +PGE++
Sbjct: 583 SVQGGHNNNPDTQRQGTPGEKN 604
Score = 53.1 bits (126), Expect = 5e-06
Identities = 127/658 (19%), Positives = 215/658 (32%), Gaps = 102/658 (15%)
Query: 1218 RQTRKDKQSGDGSRHSG--SRHHEAASWADS-SRHSQVGQEQSSGSRTSRHQGSSVSQDS 1274
R+ + G+ S H+ ++H E + ++ Q ++ +T++ S S
Sbjct: 161 REAKTHNFPGEASEHNDPKNKHLEGDEQSQEVAQDIQTTEDNEGQLKTNKPMAGSKKTSS 220
Query: 1275 DSERHSDDSERLSGSASRNHHGSSREQSRDGSRHPGFHQEDRASHGHSADSSR-----QS 1329
+ER D E S+ +REQS R QE + S +
Sbjct: 221 PTERKGQDKE-----ISQEGDEPAREQSVSKIRDQFGEQEGNLATQSSPPKEATQRPCED 275
Query: 1330 GTHHTESSSHGQAVSSHEQARSSPGERHGSRHQQSADSSRHSGIGHRQASSAVR--DSGH 1387
TE H Q P +H +Q+A S + R D+
Sbjct: 276 QEVRTEKEKHSNIQEPPLQREDEPSSQHADLPEQAAARSPSQTQKSTDSKDVCRMFDTQE 335
Query: 1388 RGSSGSQV---TNSEGHSEDSDTQSVSAHGQAGPHQQSHKESAR--GQSGESSGRSRSFL 1442
G Q T + G ED +G+ Q+ E+ Q G +G S +
Sbjct: 336 PGKDADQTPAKTKNLGEPED--------YGRTSETQEKECETKDLPVQYGSRNGSETSDM 387
Query: 1443 YQVSSHEQSESTHGQTAPSTGGRQGSRHEQARNSSRHSASQDGQDTIRGHPGSSRGGRQG 1502
+ HG T G Q R + R + +QDG+ S+ +G
Sbjct: 388 RDERKERRGPEAHG-----TAG-QKERDRKTRPLVLETQTQDGKYQELQGLSKSKDAEKG 441
Query: 1503 SYHEQSVDRSGHSGYHHSHTTPQGRSDASHGQSGPRSASRQTRNEEQSGDGSRHSGSRHH 1562
S + G + T +A H + G A ++N + R G+R
Sbjct: 442 SETQYLSSEGGDQTHPELEGTAVSGEEAEHTKEGTAEAFVNSKNAPAA---ERTLGAR-- 496
Query: 1563 EPSTRAGSSRHSQVGQGESAGSKTSRRQGSSVSQDRDSEGHSEDSE--RRSESASRNHYG 1620
E + VG+ ++ ++ V ++ +G +S + E +S
Sbjct: 497 ERTQDLAPLEKQSVGEN----TRVTKTHDQPVEEEDGYQGEDPESPFTQSDEGSSETPNS 552
Query: 1621 SAREQSRHGSRNPRSHQEDRASHGHSAESSRQSGTRHAETSSGGQAASSQEQARSSPGER 1680
A E+ N S + G S+ G +H E+ GG + Q + +PGE+
Sbjct: 553 LASEEG-----NSSSETGELPVQG----DSQSQGDQHGESVQGGHNNNPDTQRQGTPGEK 603
Query: 1681 HGS------------------RHQQSADSSTDSGTGRRQDSSVVGDSGNRGSSGSQASDS 1722
+ + + Q + + G G + + V +G+ + S A D
Sbjct: 604 NRALEAVVPAVRGEDVQLTEDQEQPARGEHKNQGPGTKGPGAAVEPNGHPEAQESTAGDE 663
Query: 1723 E---------GHSEESDTQSVSAHGQAGPHQQSHQESTRGQSG-ERSGR----------- 1761
G +E T +S G ++ +G S E GR
Sbjct: 664 NRKSLEIEITGALDEDFTDQLSLMQLPGKGDSRNELKVQGPSSKEEKGRATEAQNTLLES 723
Query: 1762 -----SGSFLYQVSTHEQSESAHGRTGP----STGGRQRSRHEQARDSSRHSASQEGQ 1810
S S Q+ T E S P GG Q+S ++ +SS +S E Q
Sbjct: 724 LDEDNSASLKIQLETKEPVTSEEEDESPQELAGEGGDQKSPAKKEHNSSVPWSSLEKQ 781
Score = 51.2 bits (121), Expect = 2e-05
Identities = 129/730 (17%), Positives = 239/730 (32%), Gaps = 118/730 (16%)
Query: 1795 EQARDSSRHSASQEGQDTIRGHPGSSRGGRQGSHYEQSVDSSGHSGSHHSHTTSQERSDV 1854
E+ D + + +GQ T+ P + S SG+ ++ R
Sbjct: 105 EKLDDVDVQATTGDGQWTVGTSPTQEKRMLPSGMASSSQLIPEESGAVGNNRVDPWREAK 164
Query: 1855 SRGQSGSRSVSRQTRNEKQSGDGSRHSGSRHHEASSRADS---SRHSQVGQGQSSGPRTS 1911
+ G S +N+ GD ++ + + + + G ++S P
Sbjct: 165 THNFPGEASEHNDPKNKHLEGDEQSQEVAQDIQTTEDNEGQLKTNKPMAGSKKTSSPTER 224
Query: 1912 RNQGSSVSQDSDSQGHSEDSERWSGSASRNHLGSAWEQS--RDGSRHPGSHHEDRAGHGH 1969
+ Q +SQ+ D + + A + S ++ ++ P E R
Sbjct: 225 KGQDKEISQEGDEPAREQSVSKIRDQFGEQEGNLATQSSPPKEATQRPCEDQEVRT---- 280
Query: 1970 SADSSRQSGTRHTESSSRGQAASSHEQARSSAGERHGSHHQLQSADS--------SRHSG 2021
+ + S + + +S H A R S Q +S DS ++ G
Sbjct: 281 --EKEKHSNIQEPPLQREDEPSSQHADLPEQAAARSPSQTQ-KSTDSKDVCRMFDTQEPG 337
Query: 2022 IGHGQASSAVRDSGHRGYSG--SQASDSEGHSEDSDTQSVSAQGKAGPHQQSHKESARGQ 2079
Q + ++ G G S+ + E ++D Q S G + ++ RG
Sbjct: 338 KDADQTPAKTKNLGEPEDYGRTSETQEKECETKDLPVQYGSRNGSETSDMRDERKERRGP 397
Query: 2080 SGESSGRSGSFLYQVSTHEQSESTHGQSAPSTGGRQGSHYDQAQDSSRHSASQEGQDTIR 2139
E+ G +G T T Q Y + Q S+ +++G +T
Sbjct: 398 --EAHGTAGQKERDRKTRPLVLETQTQDGK---------YQELQGLSKSKDAEKGSET-- 444
Query: 2140 GHPGPSRGGRQGSHQEQSVDRSGHSGSHHSHTTSQGRSDASRGQSGSRSASRKTYDKEQS 2199
S GG Q + + SG H T +G ++A + +A R +E++
Sbjct: 445 -QYLSSEGGDQTHPELEGTAVSGEEAEH----TKEGTAEAFVNSKNAPAAERTLGARERT 499
Query: 2200 GDGSRHSGSHHHEASSWADSSRHSLVGQGQSSGPRTSRPRGSSVSQDSDSEGHSEDSERR 2259
D + L Q R ++ V ++ +G +S
Sbjct: 500 QDLA-------------------PLEKQSVGENTRVTKTHDQPVEEEDGYQGEDPESP-- 538
Query: 2260 SGSASRNHHGSAQEQSRDGSRHPRSHHEDRAGHGHSAESSRQSGTHHAENSSGGQAASSH 2319
+++ GS++ + S S E G S+ G H E+ GG +
Sbjct: 539 ---FTQSDEGSSETPNSLASEEGNSSSE--TGELPVQGDSQSQGDQHGESVQGGHNNNPD 593
Query: 2320 EQARSSAGERHGS------------------HHQQSADSSRHSGIGHGQASSAVRDSGHR 2361
Q + + GE++ + Q + ++ G G +AV +GH
Sbjct: 594 TQRQGTPGEKNRALEAVVPAVRGEDVQLTEDQEQPARGEHKNQGPGTKGPGAAVEPNGHP 653
Query: 2362 GSSGSQASDSE---------GHSEDSDTQSVSAHGQAGPHQQSHQESTRGRSA----GRS 2408
+ S A D G ++ T +S G ++ +G S+ GR+
Sbjct: 654 EAQESTAGDENRKSLEIEITGALDEDFTDQLSLMQLPGKGDSRNELKVQGPSSKEEKGRA 713
Query: 2409 GRSGSFLYQ-------------------VSTHEQSESAHGRTGTSTGGRQGSHHKQARDS 2449
+ + L + V++ E+ ES G GG Q S K+ +S
Sbjct: 714 TEAQNTLLESLDEDNSASLKIQLETKEPVTSEEEDESPQELAG--EGGDQKSPAKKEHNS 771
Query: 2450 SRHSTSQEGQ 2459
S +S E Q
Sbjct: 772 SVPWSSLEKQ 781
Score = 50.8 bits (120), Expect = 3e-05
Identities = 125/674 (18%), Positives = 224/674 (33%), Gaps = 105/674 (15%)
Query: 352 SSRQSGTRHAETSSRGQTASSHEQARSSPGERHGSGHQQSADSSRHSATGRGQASSAVSD 411
++R R A+T + AS H + P +H G +QS + ++ T ++
Sbjct: 154 NNRVDPWREAKTHNFPGEASEH----NDPKNKHLEGDEQSQEVAQDIQTTEDNEGQLKTN 209
Query: 412 RGHRGSS---------GSQASDSEGHSENSDTQSVS------GHGKAGLRQQSH--QEST 454
+ GS G S+ E + QSVS G + L QS +E+T
Sbjct: 210 KPMAGSKKTSSPTERKGQDKEISQEGDEPAREQSVSKIRDQFGEQEGNLATQSSPPKEAT 269
Query: 455 RGRSGERSGRSGSSLYQ------VSTHEQPDSAHGRTGTSTGGRQGSHHEQARDSS---R 505
+ ++ R+ + + ++P S H R S +++ DS R
Sbjct: 270 QRPCEDQEVRTEKEKHSNIQEPPLQREDEPSSQHADLPEQAAARSPSQTQKSTDSKDVCR 329
Query: 506 HSASQEGQDTIRGHPGSSRG-------GRQGSHHEQSV----------NRSGHSGSHHSH 548
+QE P ++ GR E+ +R+G S
Sbjct: 330 MFDTQEPGKDADQTPAKTKNLGEPEDYGRTSETQEKECETKDLPVQYGSRNGSETSDMRD 389
Query: 549 TTSQGRSDASHGQSGSRSASRQTRN---EEQSGDGT------------RHSGSRHHEASS 593
+ R +HG +G + R+TR E Q+ DG GS SS
Sbjct: 390 ERKERRGPEAHGTAGQKERDRKTRPLVLETQTQDGKYQELQGLSKSKDAEKGSETQYLSS 449
Query: 594 QADSSRHSQVGQGQSSGPRTSRNQGSSVSQDSDSQGHSEDSERWSGSASRNHHGSAQEQS 653
+ H ++ SG + + +S+ ++ +ER G+ R + E+
Sbjct: 450 EGGDQTHPELEGTAVSGEEAEHTKEGTAEAFVNSK-NAPAAERTLGARERTQDLAPLEKQ 508
Query: 654 RDG--SRHPRSHHED-RAGHGHSADSSRKSGTRHTQNSSSGQAASSHEQARSSAGERHGS 710
G +R ++H + G+ + T+ + SS + + E+ SS+
Sbjct: 509 SVGENTRVTKTHDQPVEEEDGYQGEDPESPFTQSDEGSSETPNSLASEEGNSSS-----E 563
Query: 711 RHQLQSADSSRHSGTGHGQASSAVRDSGHRGSSGSQATDSEGHSEDSDTQSVSGHGQAGH 770
+L S+ G HG++ GH+ + DTQ G+
Sbjct: 564 TGELPVQGDSQSQGDQHGESVQG------------------GHNNNPDTQRQGTPGEKNR 605
Query: 771 HQQSHQESARDRSGERSRRSGSFLYQVSTHKQSESSHGWTGPSTGVRQGSHHEQARDNSR 830
++ + R + + Q + + G GP V H E +
Sbjct: 606 ALEAVVPAVRGEDVQLTEDQE----QPARGEHKNQGPGTKGPGAAVEPNGHPEAQESTAG 661
Query: 831 HSASQDGQDTIRGHPGSSRRGRQGSHHEQSVDRSGHSGSHHSHTTSQGRSDASRGQSGSR 890
+ + I G + + S+ + G + QG S S+ + G
Sbjct: 662 DENRKSLEIEITGALD------EDFTDQLSLMQLPGKGDSRNELKVQGPS--SKEEKGRA 713
Query: 891 SASRTTRNEEQSRDGSR----HSGSRHHEASSHADISRHSQAGQGQSEGSRTSRRQGSSV 946
+ ++ T E D S ++ S D S AG+G + S + SSV
Sbjct: 714 TEAQNTLLESLDEDNSASLKIQLETKEPVTSEEEDESPQELAGEGGDQKSPAKKEHNSSV 773
Query: 947 SQDSDSEGHSEDSE 960
S + D E
Sbjct: 774 PWSSLEKQMQRDQE 787
Score = 45.8 bits (107), Expect = 9e-04
Identities = 118/615 (19%), Positives = 203/615 (33%), Gaps = 117/615 (19%)
Query: 963 SGSASRNHRGSAQEQSRHGSRHPRSHHEDRAGHGHSADSSRQSGTPHAETSSG--GQAAS 1020
SG+ N +E H S H D D Q +T+ GQ +
Sbjct: 149 SGAVGNNRVDPWREAKTHNFPGEASEHNDPKNKHLEGDEQSQEVAQDIQTTEDNEGQLKT 208
Query: 1021 SHEQA----RSSPGERHGSRHQQSADSSRHSGIPRRQASSAVRDS--GHWGSSGSQAS-- 1072
+ A SSP ER G + S + + R Q+ S +RD G+ +Q+S
Sbjct: 209 NKPMAGSKKTSSPTERKGQDKEISQEGDEPA---REQSVSKIRDQFGEQEGNLATQSSPP 265
Query: 1073 ---------DSEGHSEE---SDTQSVSGHGQDGPHQQS----HQESARDWSGGRSGRSGS 1116
D E +E+ S+ Q +D P Q Q +AR S +
Sbjct: 266 KEATQRPCEDQEVRTEKEKHSNIQEPPLQREDEPSSQHADLPEQAAARSPSQTQKSTDSK 325
Query: 1117 FIYQVSTHEQSESAHGRTRTSTGRRQGSHHEQARDSSRHSASQEGQDTIRAHPGSRRGGR 1176
+ ++ ++ +T T + G + R S E +D + GSR G
Sbjct: 326 DVCRMFDTQEPGKDADQTPAKT-KNLGEPEDYGRTSETQEKECETKD-LPVQYGSRNGSE 383
Query: 1177 QGSHHEQSVDRSGHSGSHHSHTTSQGRSDASHGQSGSRSASRQTRK---DKQSGDG---- 1229
++ +R G +HG +G + R+TR + Q+ DG
Sbjct: 384 TSDMRDERKERRGPE---------------AHGTAGQKERDRKTRPLVLETQTQDGKYQE 428
Query: 1230 --------SRHSGSRHHEAASWADSSRHSQVGQEQSSGSRTSRHQGSSVSQDSDSERHSD 1281
GS +S H ++ SG + H ++ + +++
Sbjct: 429 LQGLSKSKDAEKGSETQYLSSEGGDQTHPELEGTAVSGEE-AEHTKEGTAEAFVNSKNAP 487
Query: 1282 DSERLSGSASRNHHGSSREQSRDG-------------SRHPGFHQEDRASHGHSADSSRQ 1328
+ER G+ R + E+ G G+ ED S +D
Sbjct: 488 AAERTLGARERTQDLAPLEKQSVGENTRVTKTHDQPVEEEDGYQGEDPESPFTQSDEG-S 546
Query: 1329 SGTHHTESSSHGQAVSSHEQA-----RSSPGERHGSR----HQQSADSSRHSGIGHRQAS 1379
S T ++ +S G + S + S G++HG H + D+ R G + +
Sbjct: 547 SETPNSLASEEGNSSSETGELPVQGDSQSQGDQHGESVQGGHNNNPDTQRQGTPGEKNRA 606
Query: 1380 SAVRDSGHRGSSGSQVTNSEGHSEDSDTQSVSAHGQAGP---------HQQSHKESARGQ 1430
RG Q+T ED + + H GP H E+
Sbjct: 607 LEAVVPAVRGED-VQLT------EDQEQPARGEHKNQGPGTKGPGAAVEPNGHPEAQEST 659
Query: 1431 SGESSGRSRSF---------------LYQVSSHEQSESTHGQTAPSTGGRQGSRHEQARN 1475
+G+ + +S L Q+ S + PS+ +G R +A+N
Sbjct: 660 AGDENRKSLEIEITGALDEDFTDQLSLMQLPGKGDSRNELKVQGPSSKEEKG-RATEAQN 718
Query: 1476 SSRHSASQDGQDTIR 1490
+ S +D +++
Sbjct: 719 TLLESLDEDNSASLK 733
Score = 45.4 bits (106), Expect = 0.001
Identities = 89/502 (17%), Positives = 175/502 (34%), Gaps = 58/502 (11%)
Query: 2102 STHGQSAPSTGGRQGSH-YDQAQDSSRHSASQEGQDTIRGHPGPSRGGRQGSHQEQSVDR 2160
++ Q P G G++ D +++ H+ E + H P +G Q Q V +
Sbjct: 139 ASSSQLIPEESGAVGNNRVDPWREAKTHNFPGEASE----HNDPKNKHLEGDEQSQEVAQ 194
Query: 2161 SGHSGSHHSHTTSQGRSDASRGQSGSRSASRKTYDKEQSGDGSRHSGSHHHEASSWADSS 2220
+ + +G+ ++ +GS+ S T K Q + S+ E S
Sbjct: 195 DIQTTEDN-----EGQLKTNKPMAGSKKTSSPTERKGQDKEISQEGDEPAREQS--VSKI 247
Query: 2221 RHSLVGQGQSSGPRTSRPRGSSVSQDSDSEGHSEDSERRSGSASRNHHGSAQEQSRDGSR 2280
R Q + ++S P+ ++ D E +E + H + QE
Sbjct: 248 RDQFGEQEGNLATQSSPPKEATQRPCEDQEVRTE----------KEKHSNIQEPPLQRED 297
Query: 2281 HPRSHHEDRAGHGHSAESSRQSGTHHAEN-------SSGGQAASSHEQARSSAGERHG-- 2331
P S H D + S+ + +++ G+ A + GE
Sbjct: 298 EPSSQHADLPEQAAARSPSQTQKSTDSKDVCRMFDTQEPGKDADQTPAKTKNLGEPEDYG 357
Query: 2332 ------SHHQQSADSSRHSGIGHGQASSAVRDSGHRGSSGSQASDSEGHSE-DSDTQSVS 2384
++ D G +G +S +RD + G +A + G E D T+ +
Sbjct: 358 RTSETQEKECETKDLPVQYGSRNGSETSDMRDE-RKERRGPEAHGTAGQKERDRKTRPLV 416
Query: 2385 AHGQAGPHQQSHQESTRGRSAGRSGRSGSFLYQVSTHEQSESAHGRTGTSTGGRQGSHHK 2444
Q Q + +G S + GS +S+ ++ GT+ G + H K
Sbjct: 417 LETQT---QDGKYQELQGLSKSKDAEKGSETQYLSSEGGDQTHPELEGTAVSGEEAEHTK 473
Query: 2445 ----QARDSSRHSTSQEGQDTIHGHPGSSSGGRQGSHYEQLVDRSGHSGSHHSHTTSQGR 2500
+A +S+++ + E + G R+ + +++ + T
Sbjct: 474 EGTAEAFVNSKNAPAAE----------RTLGARERTQDLAPLEKQSVGENTRVTKTHDQP 523
Query: 2501 SDASHGHSGSRSASRQTRNDEQSGDGSRHSGSRHHEASSRADSSGHSQVGQGQSEGPRTS 2560
+ G+ G S T++DE S + S E +S +++ G QS+G +
Sbjct: 524 VEEEDGYQGEDPESPFTQSDEGSSETPNSLAS--EEGNSSSETGELPVQGDSQSQGDQHG 581
Query: 2561 RNWGSSFSQDSDSQGHSEDSER 2582
+ + + D+Q E+
Sbjct: 582 ESVQGGHNNNPDTQRQGTPGEK 603
Score = 40.8 bits (94), Expect = 0.028
Identities = 91/483 (18%), Positives = 163/483 (33%), Gaps = 65/483 (13%)
Query: 3529 PRTSRNQGSSVSQDSDSQGHSEDSERWSGSASRNHRGSAQEQSRDGSRHPTSHHEDRAGH 3588
P + + ++S + G++ + W + + N G A E + ++H + +
Sbjct: 135 PSGMASSSQLIPEESGAVGNNR-VDPWREAKTHNFPGEASEHNDPKNKHLEGDEQSQEVA 193
Query: 3589 GHSAESSRQSGTHHAENSSGGQAASSHEQARSSAGERHGSHHQQSADSSRHSGI----GH 3644
+ G G +S R + + A S I G
Sbjct: 194 QDIQTTEDNEGQLKTNKPMAGSKKTSSPTERKGQDKEISQEGDEPAREQSVSKIRDQFGE 253
Query: 3645 GQASSAVRDSGHRGSSGSQASDSEGHSEDSDTQSVSAHGQAGPHQQSHQ-----ESTRGR 3699
+ + A + S + ++ D E +E ++ + S Q E R
Sbjct: 254 QEGNLATQSSPPKEATQRPCEDQEVRTEKEKHSNIQEPPLQREDEPSSQHADLPEQAAAR 313
Query: 3700 SAGRSGRSGSFLYQVSTHEQSESAHGRAGPSTGGRQGSRHEQARDSSRHSASQEGQDTIR 3759
S ++ +S + E G+ T + + E D R S +QE + +
Sbjct: 314 SPSQTQKSTDSKDVCRMFDTQEP--GKDADQTPAKTKNLGEP-EDYGRTSETQEKECETK 370
Query: 3760 GHP---GSRRGGRQGSYHEQSVDRSGHSGSHHSHTTSQGRSDASHGQSGSRSASRETRN- 3815
P GSR G ++ +R G +HG +G + R+TR
Sbjct: 371 DLPVQYGSRNGSETSDMRDERKERRGPE---------------AHGTAGQKERDRKTRPL 415
Query: 3816 --EEQSGDGSRHSGSRHHEASTQADSSRHSQSGQGESAGSRRSRRQGSSVS---QDSDSE 3870
E Q+ DG ++ + S A+ +Q E +G++VS + E
Sbjct: 416 VLETQTQDG-KYQELQGLSKSKDAEKGSETQYLSSEGGDQTHPELEGTAVSGEEAEHTKE 474
Query: 3871 AYPEDSERRSESASRNHHGSSREQSRD----GSRHPGSSHRDTASHVQ------------ 3914
E + + +RE+++D + G + R T +H Q
Sbjct: 475 GTAEAFVNSKNAPAAERTLGARERTQDLAPLEKQSVGENTRVTKTHDQPVEEEDGYQGED 534
Query: 3915 -SSP-VQSD-------SSTAKEHGHFSSLSQDSAYHSGIQSRGSPHSSS--SYHYQSEGT 3963
SP QSD +S A E G+ SS + + QS+G H S H + T
Sbjct: 535 PESPFTQSDEGSSETPNSLASEEGNSSSETGELPVQGDSQSQGDQHGESVQGGHNNNPDT 594
Query: 3964 ERQ 3966
+RQ
Sbjct: 595 QRQ 597
>gi|117414137 retinitis pigmentosa 1-like 1 [Homo sapiens]
Length = 2400
Score = 89.7 bits (221), Expect = 5e-17
Identities = 390/2061 (18%), Positives = 675/2061 (32%), Gaps = 309/2061 (14%)
Query: 439 GHGKAGLRQQSHQESTRGRSGERSGRSGSSLYQVSTHEQPDSAHGRTGTSTGGRQGSHHE 498
GHG AG R++ Q+S S S + L + S +P+S+ G S
Sbjct: 439 GHGTAG-RERCSQDSA-------SPASSTGLPEGS---EPESSCCPRTPEDGVDSASPSA 487
Query: 499 QARDSSRHSASQEGQDTIRGHPGSSRGG---------RQGSHHEQSVNRSGHSGSHHSHT 549
Q + R + G+D G+ GG R S S + S +GSH +
Sbjct: 488 QI-GAERKAGGSLGEDPGLCIDGAGLGGPEQGGRLTPRARSEEGASSDSSASTGSHEGSS 546
Query: 550 TSQGRSDASHGQSGSRSASRQTRNEEQSGDGTRHSGSRHHEASSQADSSRHSQVGQG--Q 607
GR G++ R +++++ +G + +S ++D + GQG Q
Sbjct: 547 EWGGRPQGCPGKA------RAETSQQEASEGGDPASPALSLSSLRSDDLQAETQGQGTEQ 600
Query: 608 SSGPRTSRNQ---GSSVSQDSDSQGHSEDSERWSGSASRNHHGSAQEQSRDGSR------ 658
++G +R G S S DS+ + + S R H A S S
Sbjct: 601 ATGAAVTREPLVLGLSCSWDSEGASSTPSTCTSSQQGQRRHRSRASAMSSPSSPGLGRVA 660
Query: 659 ---HPRSHHEDRAGHGHSADSSRKSGTRHTQNSSSGQAASSHEQARSSAGERHGSRHQLQ 715
HPR H + H S K R + + Q S + SS+ R + L+
Sbjct: 661 PRGHPRHSHYRKDTHSPLDSSVTKQVPRPPERRRACQDGSVPRYSGSSSSTRTQASGNLR 720
Query: 716 -----SADSSRHSGTGHGQASSAVRDSGHRGSSGSQATDSEGHSEDSDTQSVSGHGQAGH 770
S S GT + AV G S A S G + D+ +++ S H
Sbjct: 721 PPSSGSLPSQDLLGTSSATVTPAVHSDFVSGVSPHNAP-SAGWAGDAGSRTCSPAPIPPH 779
Query: 771 HQQSHQESARDRSGERSRR----SGSFLYQVSTHKQS----ESSHGWTGPSTGVRQGSHH 822
S +S GE +R S + QV +Q SH + P T Q
Sbjct: 780 TSDSCSKSGAASLGEEARDTPQPSSPLVLQVGRPEQGAVGPHRSHCCSQPGTQPAQ---- 835
Query: 823 EQARDNSRHSASQDGQ---DTIRGHPGSSRR----GRQGSHHEQSVDRSGHSGSHHSHTT 875
E R S ++ G+ RG P RR G GS H+ + G GS T
Sbjct: 836 EAQRGPSPEASWLCGRYCPTPPRGRPCPQRRSSSCGSTGSSHQSTA--RGPGGSPQEGTR 893
Query: 876 SQG-------RSDASRGQSGSRSA-SRTTRNEEQSRDGSRHSGSRHHEASSHADISRHSQ 927
G S ASR S S+ A SR E+ R G G + S S
Sbjct: 894 QPGPTPSPGPNSGASRRSSASQGAGSRGLSEEKTLRSGGGPQGQE--------EASGVSP 945
Query: 928 AGQGQSEGSRTSRRQGSSVSQDSDSEGHSEDSERWSGSASRNHRGSAQEQSRHGSRHPRS 987
+ +S R ++ ++ + E ++ +G+A RG + P
Sbjct: 946 SSLPRSSPEAVVREWLDNIPEEPILMTY-ELADETTGAAGGGLRGPEVD--------PGD 996
Query: 988 HHEDRAGHGHSADSSRQS--GTPHAETS-SGGQAASSHEQARSSPGERHGSRHQQSADSS 1044
H G G A + +QS G P + G SS +S G G+ + +++
Sbjct: 997 DHS-LEGLGEPAQAGQQSLEGDPGQDPEPEGALLGSSDTGPQSGEGVPQGAAPEGVSEAP 1055
Query: 1045 RHSGIPRRQASSAVRDSGHWGSSGSQASDSEGHSEESDTQSVSGHGQDGPHQQSHQESAR 1104
+G R +A + R S +A + +++ G Q P S E +R
Sbjct: 1056 AEAGADR-EAPAGCRVS-------LRALPGRVSASTQIMRALMGSKQGRP--SSVPEVSR 1105
Query: 1105 DWSGGRSGRSGSFIYQVSTHEQSESAHGRTRTSTGRRQGSHHEQARDSSRH--SASQEGQ 1162
+ S +G+ I +++ + E G + + +++ S+ G+
Sbjct: 1106 PMARRLSCSAGALITCLASLQLFEEDLGSPASKVRFKDSPRYQELLSISKDLWPGCDVGE 1165
Query: 1163 DTIRAHPGSRRGGRQGSHHEQSVDRSGHSGSHHSHTTSQGRSDASHGQSGSRSASRQTRK 1222
D + + G + + + D H+ + + TS D S G GS +S
Sbjct: 1166 DQLDS------GLWELTWSQALPDLGSHAMTENFTPTSSSGVDISSGSGGSGESSVPCAM 1219
Query: 1223 D----KQSGD-----GSRHSGSRHHEAASWADSSRHSQVGQEQSSGSRTSRHQGSSVSQD 1273
D Q + ++ SR +E+ ++ + ++ + +D
Sbjct: 1220 DGTLVTQGTELPLKTSNQRPDSRTYESPGDLENQQQCCFPTFLNARACACATNEDEAERD 1279
Query: 1274 SDSERHSDDSERLSGSASRNHHGSSREQSRDGSRHPGFHQ------EDRASHGHSADSSR 1327
S+ +R S + E+L+ + + E++++G+ G + E + G + +
Sbjct: 1280 SEEQRASSNLEQLAENTVQEE--VQLEETKEGTEGEGLQEEAVQLEETKTEEGLQEEGVQ 1337
Query: 1328 QSGTHHTESSSH--------------GQAVSSH----EQARSSP-----GE--------- 1355
T TE G+ + E+ + P GE
Sbjct: 1338 LEETKETEGEGQQEEEAQLEEIEETGGEGLQEEGVQLEEVKEGPEGGLQGEALEEGLKEE 1397
Query: 1356 ---RHGSRH-QQSADSSRHSGIGHRQASSAVRDSGHRGSSGSQVTNSEGHSEDSDTQSVS 1411
GS H Q+ +++S G G ++ + R S+ ++ +EG E T+ S
Sbjct: 1398 GLPEEGSVHGQELSEASSPDGKGSQEDDPVQEEEAGRASASAEPCPAEGTEEP--TEPPS 1455
Query: 1412 AHGQAGPHQQSHKESARGQSGESSGRSRSFLYQVSSHEQSESTHGQTAPSTGGRQGSRHE 1471
+ P + ++ + G + + Q H Q P+ G + S
Sbjct: 1456 HLSETDPSASERQSGSQLEPGLEKPPGATMMGQ---------EHTQAQPTQGAAERS--- 1503
Query: 1472 QARNSSRHSASQD------------GQDTIRGHPGSSRGGRQGSYHEQSVDRSGHSGYHH 1519
+S SA+ D + H S+ + + Q D
Sbjct: 1504 ---SSVACSAALDCDPIWVSVLLKKTEKAFLAHLASAVAELRARWGLQDNDLLDQMAAEL 1560
Query: 1520 SHTTPQGRSDAS-------HGQSGPRSASRQTRNEEQSGDGSRHSGSRHHEPSTRAGSSR 1572
Q D++ G++G R R E +G+ + R H S
Sbjct: 1561 QQDVAQRLQDSTKRELQKLQGRAG-RMVLEPPR-EALTGELLLQTQQRRHRLRGLRNLSA 1618
Query: 1573 HSQVGQGESAGSKT-------SRRQGSSVSQDRDSEGH-----------SEDSERRSESA 1614
S+ G S T S GS + ++ + E S S + + A
Sbjct: 1619 FSERTLGLGPLSFTLEDEPALSTALGSQLGEEAEGEEFCPCEACVRKKVSPMSPKATMGA 1678
Query: 1615 SRNHYGSAREQSRHGSRNPRSHQEDRASHGHSAESSRQ-SGTRHAETSSGGQAASSQEQA 1673
+R A + + R H + A+ ++ + TR + + GG +
Sbjct: 1679 TRGPIKEAFDLQQILQRKRGEHTDGEAAEVAPGKTHTDPTSTRTVQGAEGGLGPGLSQGP 1738
Query: 1674 RSSPGERHGSRHQQSADSSTDSGTGRRQDSSVVGDSGNRGSSGSQASDSEGHSEESDTQS 1733
GE Q + D G + ++ + + + ++ SE E + +
Sbjct: 1739 GVDEGE--DGEGSQRLNRDKDPKLGEAEGDAMAQEREGKTHNSETSAGSELGEAEQEGEG 1796
Query: 1734 VSAHGQAGPHQQSHQESTRGQS--------GERSGRSGSFLYQVSTHEQSESAHGRTGPS 1785
+S G+ G H+++ +G++ G+ G G + Q ES G P
Sbjct: 1797 ISERGETGGQGSGHEDNLQGEAAAGGDQDPGQSDGAEGIEAPEAEGEAQPES-EGVEAPE 1855
Query: 1786 TGGRQRSRHEQARDSSRHSASQEGQDTIRGHPGSSRGGRQGSHYEQSVDSSGHSGSHHSH 1845
G + +A+ S + E + P S + +E +S G
Sbjct: 1856 AEGDAQEAEGEAQPESEDVEAPEAEG--EAQPESEDVETPEAEWEVQPESEGAEAPEAEK 1913
Query: 1846 TTSQERSDVSRGQSGSRSVSRQTRNEKQSGDGSRHSGSRHHEASSRADSSRHSQVGQGQS 1905
E V E + D G+ EA A Q +GQ+
Sbjct: 1914 EAQPETESVEA-------------LETEGEDEPESEGAEAQEAEEAA------QEAEGQT 1954
Query: 1906 SGPRTSRNQGSSVSQDSDSQGHSEDSERWSGSASRNHLGSAWEQSRDGSRHPGSHHEDRA 1965
P + + S + ++Q SED E Q +G P S +
Sbjct: 1955 Q-PESEVIE--SQEAEEEAQPESEDVEALEVEVET--------QEAEGEAQPESEDVEAP 2003
Query: 1966 GHGHSADSSRQSGTRHTESSSRG---QAASSHEQARSSAGERHGSHHQLQSADSSRHSGI 2022
A+ Q + S G Q S E+A+ GE + Q
Sbjct: 2004 ----EAEGEMQEAEEEAQPESDGVEAQPKSEGEEAQEVEGETQKTEGDAQPESD------ 2053
Query: 2023 GHGQASSAVRDSGHRGYSGSQASDSEGHSEDSDTQSVSAQGKAGPHQQSHKESARGQSGE 2082
G + + Q ++ E H E D + A+G+A P +S A GE
Sbjct: 2054 --GVEAPEAEEEAQEAEGEVQEAEGEAHPESEDVDAQEAEGEAQP--ESEGVEAPEAEGE 2109
Query: 2083 SSGRSGSFLYQVSTHEQSES-------THGQSAPSTGG-----RQGSHYDQAQDSSRHSA 2130
+ G + Q ES G++ P + G +G +++ A
Sbjct: 2110 AQKAEGIEAPETEGEAQPESEGIEAPEAEGEAQPESEGVEAQDAEGEAQPESEGIEAQEA 2169
Query: 2131 SQEGQDTIRGHPGPSRGGRQGSHQEQSVDRSGHSGSHHSHTTSQGRSDASRGQSGSRSAS 2190
+E Q + G P +G Q +S + +G +A + ++
Sbjct: 2170 EEEAQPELEGVEAPE---AEGEAQPESEGIEAPEAEGEAQPELEG-VEAPEAEEEAQPEP 2225
Query: 2191 RKTYDKEQSGDGSRHSGSHHHEASSWADSSRHSLVGQGQSSGPRTSRPRGSSVSQDSDSE 2250
E G+ S E S +G GQS S S V +D +
Sbjct: 2226 EGVETPEAEGEAQPES---EGETQGEKKGSPQVSLGDGQSEEASES---SSPVPEDRPTP 2279
Query: 2251 GHSEDSERRSGSASRNHHGSAQEQSRDGSRHPRSHHEDRAGHGHSAESSRQSGTHHAENS 2310
S + S+ S G+ + D + ++ +GT HAE
Sbjct: 2280 PPSPGGDTPHQRPGSQTGPSSSRASSWGNCWQKDSENDHVLGDTRSPDAKSTGTPHAERK 2339
Query: 2311 SGGQ--AASSHEQARSSAGER 2329
+ +S+ EQ + G R
Sbjct: 2340 ATRMYPESSTSEQEEAPLGSR 2360
Score = 83.6 bits (205), Expect = 4e-15
Identities = 413/2154 (19%), Positives = 667/2154 (30%), Gaps = 338/2154 (15%)
Query: 1738 GQAGPHQQSHQESTRGQSGERSGRSGSFLYQVSTHEQSESAHGRTGPSTGGRQRSRHEQA 1797
GQ GP + GER + ++ H + G G T GR+R + A
Sbjct: 399 GQPGPKYEIWTNPLHASQGERVAARKR--WGLAQHVRCS---GLWGHGTAGRERCSQDSA 453
Query: 1798 RDSSRHSASQEGQDTIRGHPGSSRGGRQGSHYEQSVDSSGHSGSHHSHTTSQ--ERSDVS 1855
+S + + P + G + + + +G + + +
Sbjct: 454 SPASSTGLPEGSEPESSCCPRTPEDGVDSASPSAQIGAERKAGGSLGEDPGLCIDGAGLG 513
Query: 1856 RGQSGSRSVSRQTRNEKQSGDGSRHSGSRHHEASS-------------RADSSRHSQVGQ 1902
+ G R R E S D S +GS HE SS RA++S+
Sbjct: 514 GPEQGGRLTPRARSEEGASSDSSASTGS--HEGSSEWGGRPQGCPGKARAETSQQEASEG 571
Query: 1903 GQSSGPRTSRNQGSSVSQDSDSQGHSEDSERWSGSASRNH-----LGSAWEQSRDGSRHP 1957
G + P S + S +++QG + +E+ +G+A L +W+ S S P
Sbjct: 572 GDPASPALSLSSLRSDDLQAETQG--QGTEQATGAAVTREPLVLGLSCSWD-SEGASSTP 628
Query: 1958 GSHHEDRAGHGHSADSSRQSGTRHTESSSRGQAASSHEQAR-SSAGERHGSHHQLQS--- 2013
+ SS+Q RH +S + SS R + G SH++ +
Sbjct: 629 ST-----------CTSSQQGQRRHRSRASAMSSPSSPGLGRVAPRGHPRHSHYRKDTHSP 677
Query: 2014 ADSSRHSGIGHG-QASSAVRDSGHRGYSGSQAS---DSEGHSEDSDTQSVSAQGKAGPHQ 2069
DSS + + A +D YSGS +S + G+ + S+ +Q G
Sbjct: 678 LDSSVTKQVPRPPERRRACQDGSVPRYSGSSSSTRTQASGNLRPPSSGSLPSQDLLGTSS 737
Query: 2070 QSHKESARGQSGESSGRSGSFLYQVSTHEQSESTHGQSAPSTG--GRQGSHY-------- 2119
+ + F+ VS H +APS G G GS
Sbjct: 738 ATVTPAVHSD----------FVSGVSPH---------NAPSAGWAGDAGSRTCSPAPIPP 778
Query: 2120 ---DQAQDSSRHSASQEGQDTIRGHPGPSRG-GRQGSHQEQSVDRSGHSGSHHSHTTSQG 2175
D S S +E +DT P PS Q EQ G G H SH SQ
Sbjct: 779 HTSDSCSKSGAASLGEEARDT----PQPSSPLVLQVGRPEQ-----GAVGPHRSHCCSQP 829
Query: 2176 RS----DASRGQSGSRS-----------ASRKTYDKEQSGDGSRHSGSHHHEASSWADSS 2220
+ +A RG S S R + S GS S SH A S
Sbjct: 830 GTQPAQEAQRGPSPEASWLCGRYCPTPPRGRPCPQRRSSSCGSTGS-SHQSTARGPGGSP 888
Query: 2221 RHSL--VGQGQSSGPRTSRPRGSSVSQDSDSEGHSEDSERRSGSASRNHHGSAQEQSRDG 2278
+ G S GP + R SS SQ + S G SE+ RSG + G +
Sbjct: 889 QEGTRQPGPTPSPGPNSGASRRSSASQGAGSRGLSEEKTLRSGGGPQ---GQEEASGVSP 945
Query: 2279 SRHPRSHHEDRAGHGHSAESSRQSGTHHAENSSGGQAASSHEQARSSAGERHGSHHQQSA 2338
S PRS S +N ++E A + G G
Sbjct: 946 SSLPRS-------------SPEAVVREWLDNIPEEPILMTYELADETTGAAGGGLRGPEV 992
Query: 2339 D-SSRHSGIGHGQASSAVRDSGHRGSSGSQASDSEGHSE---DSDTQSVSAHG-QAGPHQ 2393
D HS G G+ + A G + G D E SDT S G G
Sbjct: 993 DPGDDHSLEGLGEPAQA----GQQSLEGDPGQDPEPEGALLGSSDTGPQSGEGVPQGAAP 1048
Query: 2394 QSHQESTRGRSAGRSGRSGSFLYQVSTHEQSESAHGRTGTST----------GGRQGSHH 2443
+ E+ A R +G +VS + GR ST GR S
Sbjct: 1049 EGVSEAPAEAGADREAPAGC---RVSL----RALPGRVSASTQIMRALMGSKQGRPSSVP 1101
Query: 2444 KQARDSSRHSTSQEGQ-----------DTIHGHPGSSSGGRQGSHYEQLVDRSGH----- 2487
+ +R +R + G + G P S + Y++L+ S
Sbjct: 1102 EVSRPMARRLSCSAGALITCLASLQLFEEDLGSPASKVRFKDSPRYQELLSISKDLWPGC 1161
Query: 2488 -------SGSHHSHTTSQGRSD-ASHGHSGSRSASRQTRNDEQSGDGSRHSGSRHHEASS 2539
T SQ D SH + + + + + D SG G GS
Sbjct: 1162 DVGEDQLDSGLWELTWSQALPDLGSHAMTENFTPTSSSGVDISSGSG----GSGESSVPC 1217
Query: 2540 RADSSGHSQVGQGQSEGPRTSRNWGSSFSQDSDSQGHSEDSERWSGSASRNHHGSAQEQL 2599
D + V QG +TS S+ +S G E+ ++ N A
Sbjct: 1218 AMDG---TLVTQGTELPLKTSNQ--RPDSRTYESPGDLENQQQCCFPTFLNARACACATN 1272
Query: 2600 RDGSRHPRSHQEDRAGHGHSADSSRQSGTRHTQTSSGGQAASSHEQA----RSSAGERHG 2655
D + Q + A+++ Q + +T G + E+A + E
Sbjct: 1273 EDEAERDSEEQRASSNLEQLAENTVQEEVQLEETKEGTEGEGLQEEAVQLEETKTEEGLQ 1332
Query: 2656 SHHQQSADSSRHSGIGHGQASSAVRDSGHRGYSGSQASDNEGHSEDSDTQSVSAHGQAGS 2715
Q ++ G G + + + + G G Q E + V + G
Sbjct: 1333 EEGVQLEETKETEGEGQQEEEAQLEEIEETGGEGLQ-------EEGVQLEEVKEGPEGGL 1385
Query: 2716 HQQSHQESARGRSGETSGHSGSFLYQVSTHEQSESSHGWTGPSTRGRQGSRHEQAQDSSR 2775
++ +E G E GS V E SE+S P +G Q Q +++ R
Sbjct: 1386 QGEALEE---GLKEEGLPEEGS----VHGQELSEAS----SPDGKGSQEDDPVQEEEAGR 1434
Query: 2776 HSASQDGQDTIRGHPGSSRGGRQGYHHEHSVDSSGHSGSHHSHTTSQGRSDASRGQSGSR 2835
SAS + P + G + SH S T AS QSGS+
Sbjct: 1435 ASASAE--------PCPAEG----------TEEPTEPPSHLSETD----PSASERQSGSQ 1472
Query: 2836 SASRTTRNEEQSGDGSRHSGSRHHEASTHADISRHSQAVQGQSEGSRRSRRQGSSVSQDS 2895
+ G+ G H +A Q QG +E RS S + D
Sbjct: 1473 LEPGL-----EKPPGATMMGQEHTQA----------QPTQGAAE---RSSSVACSAALDC 1514
Query: 2896 DSEGHSEDSERWSGSASRNHHGSAQEQLRDGSRHPRSHQEDRAGHGHSADSSR--QSGTR 2953
D S ++ + A H SA +LR + D+ D ++ Q T+
Sbjct: 1515 DPIWVSVLLKK-TEKAFLAHLASAVAELRARWGLQDNDLLDQMAAELQQDVAQRLQDSTK 1573
Query: 2954 HTQTSSGGQA----------ASSHEQARSSAGERHGSHHQQSADSSRHSGIGHGQASSAV 3003
G+A A + E + RH ++ + +G G S +
Sbjct: 1574 RELQKLQGRAGRMVLEPPREALTGELLLQTQQRRHRLRGLRNLSAFSERTLGLGPLSFTL 1633
Query: 3004 RDSGHRGYS-GSQASDNEGHSEDSDTQSVSAHGQAGSHQQSHQESARGRSGETSGHSGSF 3062
D + GSQ + E ++ + ++ + RG E
Sbjct: 1634 EDEPALSTALGSQLGEEAEGEEFCPCEACVRKKVSPMSPKATMGATRGPIKEAFDLQQIL 1693
Query: 3063 LYQVSTHEQSESSHGWTGPSTRGRQGSRHEQAQDSSRHSASQYGQDTIRGHPGSSRGGRQ 3122
+ H E++ G + +R Q + G G G G Q
Sbjct: 1694 QRKRGEHTDGEAAEVAPGKTHTDPTSTRTVQGAEGGLGPGLSQGPGVDEGEDGE---GSQ 1750
Query: 3123 GYHHEHSVDSSGHSGSHHSHTTSQGRSDASRGQSGSRSASRTTRNEEQSGDSSRHSVSRH 3182
+ D G +Q R + S + +E G S R
Sbjct: 1751 RLNR----DKDPKLGEAEGDAMAQEREGKTHNSETSAGSELGEAEQEGEGISERGETGGQ 1806
Query: 3183 ---HEASTHADISRHSQAVQGQSEGSRRSRRQGSSVSQDSDSEG----HSEDSERWSGSA 3235
HE + + + GQS+G+ + +SEG +E + +
Sbjct: 1807 GSGHEDNLQGEAAAGGDQDPGQSDGAEGIEAPEAEGEAQPESEGVEAPEAEGDAQEAEGE 1866
Query: 3236 SRNHRGSVQEQSRHGSRHPRSHH------------EDRAGHGHSADRSRQSGTRHAET-- 3281
++ V+ G P S E A++ Q T E
Sbjct: 1867 AQPESEDVEAPEAEGEAQPESEDVETPEAEWEVQPESEGAEAPEAEKEAQPETESVEALE 1926
Query: 3282 --------SSGGQAASSHEQARSSPGERHGSRHQQSADSSRHSGIPRGQASSAVRDSRHW 3333
S G +A + E A+ + G+ + + P + A+
Sbjct: 1927 TEGEDEPESEGAEAQEAEEAAQEAEGQTQPESEVIESQEAEEEAQPESEDVEALEVEVE- 1985
Query: 3334 GSSGSQASDSEGHSEESDTQSVSGHGQAGPHQQSHQESARDRSGGRSGRSGSFLYQVSTH 3393
+Q ++ E E D ++ G+ Q +E A+ S G + S
Sbjct: 1986 ----TQEAEGEAQPESEDVEAPEAEGE----MQEAEEEAQPESDGVEAQ------PKSEG 2031
Query: 3394 EQSESAHGRTRTSTGRRQ----GSHHEQARDSSRHSASQEGQDTIRGHPGSSRRGRQGSH 3449
E+++ G T+ + G Q G +A + ++ + + + HP S Q +
Sbjct: 2032 EEAQEVEGETQKTEGDAQPESDGVEAPEAEEEAQEAEGEVQEAEGEAHPESEDVDAQEAE 2091
Query: 3450 YEQSVDRSGHSGSHHSHTTSQGRS-DASRGQSGSRSASRQTRNDEQSGDGSRHS---WSH 3505
E + G + +A + ++ S E G+ S +
Sbjct: 2092 GEAQPESEGVEAPEAEGEAQKAEGIEAPETEGEAQPESEGIEAPEAEGEAQPESEGVEAQ 2151
Query: 3506 HHEASTQADSSRHSQSGQGQSAGPRTSRNQGSSVSQDSDSQGHSEDSERWSGSASRNHRG 3565
E Q +S + A P + ++ + ++ G A G
Sbjct: 2152 DAEGEAQPESEGIEAQEAEEEAQPELEGVEAPEAEGEAQPESEGIEAPEAEGEAQPELEG 2211
Query: 3566 SAQEQSRDGSRHPTSHHEDRAGHGHSAESSRQSGTHHAENSSGGQAASSHEQARSSAGER 3625
++ + ++ E G A+ + T + S + + +S
Sbjct: 2212 VEAPEAEEEAQPEPEGVETPEAEG-EAQPESEGETQGEKKGSPQVSLGDGQSEEASESSS 2270
Query: 3626 HGSHHQQSADSSRHSGIGHGQASSAVRDSGHRGSSGSQA--SDSEGHSEDSDTQSVSAHG 3683
+ + S H + S S R SS DSE DT+S A
Sbjct: 2271 PVPEDRPTPPPSPGGDTPHQRPGSQTGPSSSRASSWGNCWQKDSENDHVLGDTRSPDAKS 2330
Query: 3684 QAGPHQQSHQESTRGRSAGRSGRSGSFLY-QVSTHEQSESAHGRAGPSTGGRQG 3736
PH + R + +Y + ST EQ E+ G P G +G
Sbjct: 2331 TGTPHAE---------------RKATRMYPESSTSEQEEAPLGSRTPEQGASEG 2369
Score = 77.8 bits (190), Expect = 2e-13
Identities = 380/2036 (18%), Positives = 635/2036 (31%), Gaps = 311/2036 (15%)
Query: 1633 PRSHQE--DRASHGHSAESSRQSGTRHAETSS----GGQAASSQEQARSSPGERHGSRHQ 1686
PR+ ++ D AS + R++G E G ++ R +P +R +
Sbjct: 473 PRTPEDGVDSASPSAQIGAERKAGGSLGEDPGLCIDGAGLGGPEQGGRLTPR----ARSE 528
Query: 1687 QSADSSTDSGTGRRQDSSVVGDSGNRGSSGSQASDSEGHSEESDTQSVSAHGQAGPHQQS 1746
+ A S + + TG + SS G ++A S+ + E + A +
Sbjct: 529 EGASSDSSASTGSHEGSSEWGGRPQGCPGKARAETSQQEASEGGDPASPALSLSSLRSDD 588
Query: 1747 HQESTRGQSGERSGRSG----SFLYQVSTHEQSESAHGRTGPSTGGRQRSRHEQARDSSR 1802
Q T+GQ E++ + + +S SE A T +Q R ++R S+
Sbjct: 589 LQAETQGQGTEQATGAAVTREPLVLGLSCSWDSEGASSTPSTCTSSQQGQRRHRSRASAM 648
Query: 1803 HSASQEGQDTI--RGHPGSSRGGRQGSHYEQSVDSSGHSGSHHSHTTSQERSDVSRG--- 1857
S S G + RGHP + SHY + S S ER +
Sbjct: 649 SSPSSPGLGRVAPRGHP-------RHSHYRKDTHSPLDSSVTKQVPRPPERRRACQDGSV 701
Query: 1858 --QSGSRSVSRQ--TRNEKQSGDGSRHSGSRHHEASSRADSSRHSQVGQGQSSGPRTSR- 1912
SGS S +R + N + GS S +S+ + HS G S S
Sbjct: 702 PRYSGSSSSTRTQASGNLRPPSSGSLPSQDLLGTSSATVTPAVHSDFVSGVSPHNAPSAG 761
Query: 1913 ---NQGSSVSQDSDSQGHSEDSERWSGSAS--------------------RNHLGSAWEQ 1949
+ GS + H+ DS SG+AS R G+
Sbjct: 762 WAGDAGSRTCSPAPIPPHTSDSCSKSGAASLGEEARDTPQPSSPLVLQVGRPEQGAVGPH 821
Query: 1950 SRDGSRHPGSHHEDRAGHGHSADSSRQSGTR-----------HTESSSRGQAASSHEQ-A 1997
PG+ A G S ++S G SSS G SSH+ A
Sbjct: 822 RSHCCSQPGTQPAQEAQRGPSPEASWLCGRYCPTPPRGRPCPQRRSSSCGSTGSSHQSTA 881
Query: 1998 RSSAGERHGSHHQL-------QSADSSRHSGIGHGQASSAVRDS----------GHRGYS 2040
R G Q ++ +SR S G S + + G S
Sbjct: 882 RGPGGSPQEGTRQPGPTPSPGPNSGASRRSSASQGAGSRGLSEEKTLRSGGGPQGQEEAS 941
Query: 2041 GSQASDSEGHSEDS----------------------DTQSVSAQGKAGPH---------- 2068
G S S ++ +T + G GP
Sbjct: 942 GVSPSSLPRSSPEAVVREWLDNIPEEPILMTYELADETTGAAGGGLRGPEVDPGDDHSLE 1001
Query: 2069 -----QQSHKESARGQSGESSGRSGSFLYQVSTHEQSESTHGQSAPSTGGRQGSHYDQAQ 2123
Q+ ++S G G+ G+ L T QS G+ P +G A+
Sbjct: 1002 GLGEPAQAGQQSLEGDPGQDPEPEGALLGSSDTGPQS----GEGVPQGAAPEGVSEAPAE 1057
Query: 2124 DSSRHSASQEGQDTIRGHPGPSRGGRQGSHQEQSVDRSGHSGSHHSHTTSQGRSDASRGQ 2183
+ A + ++R PG Q + S R S G
Sbjct: 1058 AGADREAPAGCRVSLRALPGRVSASTQIMRALMGSKQGRPSSVPEVSRPMARRLSCSAGA 1117
Query: 2184 SGSRSASRKTYDKEQSGDGSR-----------------------HSGSHHHEASSWADSS 2220
+ AS + ++++ S+ G ++ W +
Sbjct: 1118 LITCLASLQLFEEDLGSPASKVRFKDSPRYQELLSISKDLWPGCDVGEDQLDSGLWELTW 1177
Query: 2221 RHSLVGQGQSSGPRTSRPRGSSVSQDSDSEGHSEDSERRSGSASRNHHGSAQEQSRDGSR 2280
+L G + P SS S G S +S + + ++
Sbjct: 1178 SQALPDLGSHAMTENFTPTSSSGVDISSGSGGSGESSVPCAMDGTLVTQGTELPLKTSNQ 1237
Query: 2281 HPRSHHEDRAGHGHSAESSRQSGTHHAENSSGGQAASSHEQA-RSSAGERHGSHHQQSAD 2339
P S + G E+ +Q N+ A++ ++A R S +R S+ +Q A+
Sbjct: 1238 RPDSRTYESPG---DLENQQQCCFPTFLNARACACATNEDEAERDSEEQRASSNLEQLAE 1294
Query: 2340 SSRHSGIGHGQASSAVRDSGHRGSSGS--QASDSEGHSEDS----DTQSVSAHGQAGPHQ 2393
++ + + G + + + EG E+ +T+ GQ
Sbjct: 1295 NTVQEEVQLEETKEGTEGEGLQEEAVQLEETKTEEGLQEEGVQLEETKETEGEGQQEEEA 1354
Query: 2394 QSHQ-ESTRGRSAGRSGRSGSFLYQVSTHEQSESAHGRTGTSTGGRQGSHHKQARDSSRH 2452
Q + E T G G V E E G G QG +A +
Sbjct: 1355 QLEEIEETGGEGLQEEG--------VQLEEVKEGPEG-------GLQG----EALEEGLK 1395
Query: 2453 STSQEGQDTIHGHPGS--SSGGRQGSHYEQLV--DRSGHSGSHHSHTTSQGRSDASHGHS 2508
+ ++HG S SS +GS + V + +G + + ++G + + S
Sbjct: 1396 EEGLPEEGSVHGQELSEASSPDGKGSQEDDPVQEEEAGRASASAEPCPAEGTEEPTEPPS 1455
Query: 2509 GSRSASRQTRNDEQSGDGSRHSGSRHHEASSRADSSGHSQVGQGQSEGPRTSRNWGSSFS 2568
S + + ++ QSG + A+ +Q QG +E S + S +
Sbjct: 1456 -HLSETDPSASERQSGSQLEPGLEKPPGATMMGQEHTQAQPTQGAAE---RSSSVACSAA 1511
Query: 2569 QDSDSQGHSEDSERWSGSASRNHHGSAQEQLRDGSRHPRSHQEDRAGHGHSADSSR--QS 2626
D D S ++ + A H SA +LR + D+ D ++ Q
Sbjct: 1512 LDCDPIWVSVLLKK-TEKAFLAHLASAVAELRARWGLQDNDLLDQMAAELQQDVAQRLQD 1570
Query: 2627 GTRHTQTSSGGQA----------ASSHEQARSSAGERHGSHHQQSADSSRHSGIGHGQAS 2676
T+ G+A A + E + RH ++ + +G G S
Sbjct: 1571 STKRELQKLQGRAGRMVLEPPREALTGELLLQTQQRRHRLRGLRNLSAFSERTLGLGPLS 1630
Query: 2677 SAVRDSGHRGYS-GSQASDNEGHSEDSDTQSVSAHGQAGSHQQSHQESARGRSGETSGHS 2735
+ D + GSQ + E ++ + ++ + RG E
Sbjct: 1631 FTLEDEPALSTALGSQLGEEAEGEEFCPCEACVRKKVSPMSPKATMGATRGPIKEAFDLQ 1690
Query: 2736 GSFLYQVSTHEQSESSHGWTGP------STRGRQGSRHEQAQDSSRHSASQDGQDTIRGH 2789
+ H E++ G STR QG+ S+ +G+D
Sbjct: 1691 QILQRKRGEHTDGEAAEVAPGKTHTDPTSTRTVQGAEGGLGPGLSQGPGVDEGEDG---- 1746
Query: 2790 PGSSRGGRQGY----HHEHSVDSSGHSGSHHSHTTSQGRSDASRGQSGSRSASRTTRNEE 2845
GS R R E + G H+ TS G Q G + R E
Sbjct: 1747 EGSQRLNRDKDPKLGEAEGDAMAQEREGKTHNSETSAGSELGEAEQEGEGISERG----E 1802
Query: 2846 QSGDGSRHSGSRHHEASTHADISRHSQAVQGQSEGSRRSRRQGSSVSQDSDSEGHSEDSE 2905
G GS H + EA+ D GQS+G+ + ++EG ++
Sbjct: 1803 TGGQGSGHEDNLQGEAAAGGDQD------PGQSDGAEG--------IEAPEAEGEAQPES 1848
Query: 2906 RWSGSASRNHHGSAQEQLRDGSRHPRSHQEDRAGHGHSADSSRQSGTRHTQT-SSGGQAA 2964
G + G AQE +G P S + A+ Q + +T + +
Sbjct: 1849 --EGVEAPEAEGDAQE--AEGEAQPESEDVE----APEAEGEAQPESEDVETPEAEWEVQ 1900
Query: 2965 SSHEQARSSAGERHGSHHQQSADSSRHSGIGHGQASSAVRDSGHRGYSGSQASDNEGHSE 3024
E A + E+ +S ++ G ++ G++A + E ++
Sbjct: 1901 PESEGAEAPEAEKEAQPETESVEALETEGEDEPES------------EGAEAQEAEEAAQ 1948
Query: 3025 DSDTQSVSAHGQAGSHQQSHQESARGRSGETSGHSGSFLYQVSTHEQSESSHGWTGPSTR 3084
+++ Q+ S Q +E A+ S + Q + E S P
Sbjct: 1949 EAEGQTQPESEVIES--QEAEEEAQPESEDVEALEVEVETQEAEGEAQPESEDVEAPEAE 2006
Query: 3085 GRQGSRHEQAQDSSRHSASQYGQDTIRGHPGSSRGGRQGYHHEHSVDSSGHSGSHHSHTT 3144
G E+AQ S D + P S G T
Sbjct: 2007 GEMQEAEEEAQPES---------DGVEAQP----------------KSEGEEAQEVEGET 2041
Query: 3145 SQGRSDASRGQSGSRSASRTTRNEEQSGDSSRHSVSRHHEASTHADISRHSQAVQGQSEG 3204
+ DA G + +E G+ H E S D Q +SEG
Sbjct: 2042 QKTEGDAQPESDGVEAPEAEEEAQEAEGEVQEAEGEAHPE-SEDVDAQEAEGEAQPESEG 2100
Query: 3205 SRRSRRQGSSVSQDS----DSEGHSE------DSERWSGSASRNHRGSVQEQSRHGSRHP 3254
+G + + ++EG ++ ++ G A G V+ Q G P
Sbjct: 2101 VEAPEAEGEAQKAEGIEAPETEGEAQPESEGIEAPEAEGEAQPESEG-VEAQDAEGEAQP 2159
Query: 3255 RSHHEDRAGHGHSADRSRQSGTRHAETSSGGQAASSHEQARSSPGERHGSRHQQSADSSR 3314
S + A + G E Q S +A + GE A +
Sbjct: 2160 ESEGIE-AQEAEEEAQPELEGVEAPEAEGEAQPESEGIEAPEAEGEAQPELEGVEAPEAE 2218
Query: 3315 HSGIP----------RGQASSAVRDSRHWGSSGS-QASDSEGHSEE-SDTQSVSGHGQAG 3362
P G+A GS Q S +G SEE S++ S +
Sbjct: 2219 EEAQPEPEGVETPEAEGEAQPESEGETQGEKKGSPQVSLGDGQSEEASESSSPVPEDRPT 2278
Query: 3363 PHQQSHQESARDRSGGRSGRSGSFLYQVST--HEQSESAH--GRTRTSTGRRQGSHHEQA 3418
P ++ R G ++G S S + SE+ H G TR+ + G+ H +
Sbjct: 2279 PPPSPGGDTPHQRPGSQTGPSSSRASSWGNCWQKDSENDHVLGDTRSPDAKSTGTPHAER 2338
Query: 3419 RDSSRHSASQEGQDTIRGHPGSSRRGRQGSHYEQSVDRSGHSGSHHSHTTSQGRSD 3474
+ + + S + P SR QG+ + GS + T + GR+D
Sbjct: 2339 KATRMYPESSTSEQ--EEAPLGSRTPEQGASEGYDLQEDQALGS-LAPTEAVGRAD 2391
Score = 70.9 bits (172), Expect = 2e-11
Identities = 154/657 (23%), Positives = 220/657 (33%), Gaps = 96/657 (14%)
Query: 1208 HGQSGSRSASRQ-------TRKDKQSGDGSRHSGSRHHEAASWADSSRHSQVGQEQSSGS 1260
H G R A+R+ R G G+ ++AS A S+ + + +SS
Sbjct: 413 HASQGERVAARKRWGLAQHVRCSGLWGHGTAGRERCSQDSASPASSTGLPEGSEPESSCC 472
Query: 1261 RTSRHQGSSVSQDSDSERHSDDSERLSGSASRNHHGSSREQSRDGSRHPGFHQEDRA--S 1318
+ G DS S +ER +G + G + + G G RA
Sbjct: 473 PRTPEDGV----DSASPSAQIGAERKAGGSLGEDPGLCIDGAGLGGPEQGGRLTPRARSE 528
Query: 1319 HGHSADSSRQSGTHHTESSSHGQAVSSHEQARSSPGERHGSRHQQSADSSRH-SGIGHRQ 1377
G S+DSS +G+H S G+ +AR+ ++ S A + S +
Sbjct: 529 EGASSDSSASTGSHEGSSEWGGRPQGCPGKARAETSQQEASEGGDPASPALSLSSLRSDD 588
Query: 1378 ASSAVRDSGHRGSSGSQVT------------NSEGHSEDSDTQSVSAHGQAGPHQQSHKE 1425
+ + G ++G+ VT +SEG S T + S G Q+ H+
Sbjct: 589 LQAETQGQGTEQATGAAVTREPLVLGLSCSWDSEGASSTPSTCTSSQQG-----QRRHRS 643
Query: 1426 SARGQSGESS---------GRSRSFLYQVSSHEQSESTHGQTAPSTGGRQGSRHEQARNS 1476
A S SS G R Y+ +H +S+ + P R R ++
Sbjct: 644 RASAMSSPSSPGLGRVAPRGHPRHSHYRKDTHSPLDSSVTKQVP----RPPERRRACQDG 699
Query: 1477 SRHSASQDGQDTIRGHPGSSRGGRQGSYHEQSVDRSGHSGYHHSHTTPQGRSDASHGQSG 1536
S S T G+ R GS Q + G + TP SD G S
Sbjct: 700 SVPRYSGSSSSTRTQASGNLRPPSSGSLPSQDL-----LGTSSATVTPAVHSDFVSGVS- 753
Query: 1537 PRSASRQTRNEEQSGD-GSRHSGSRHHEPSTRAGSSRHSQVGQGESAGSKTSRRQGSSVS 1595
P +A + +GD GSR P T S+ GE A
Sbjct: 754 PHNAP----SAGWAGDAGSRTCSPAPIPPHTSDSCSKSGAASLGEEA------------- 796
Query: 1596 QDRDSEGHSEDSERRSESASRNHYGSAREQSRHGSRNPRSHQEDRASHGHSAESSRQSGT 1655
RD+ + S R G+ H P + A G S E+S G
Sbjct: 797 --RDT---PQPSSPLVLQVGRPEQGAVGPHRSHCCSQPGTQPAQEAQRGPSPEASWLCG- 850
Query: 1656 RHAETSSGGQAASSQEQARSSPGERHGSRHQQSADSSTDS-GTGRRQDSSVVGDSGNRG- 1713
R+ T G+ Q RSS GS HQ +A S G RQ N G
Sbjct: 851 RYCPTPPRGRPC---PQRRSSSCGSTGSSHQSTARGPGGSPQEGTRQPGPTPSPGPNSGA 907
Query: 1714 ---SSGSQASDSEGHSEESDTQSVSAHGQAGPHQQSHQESTRGQSGERSGRSGSFLYQVS 1770
SS SQ + S G SEE +S GP Q S RS +
Sbjct: 908 SRRSSASQGAGSRGLSEEKTLRS-----GGGPQGQEEASGVSPSSLPRSSPEAVVREWLD 962
Query: 1771 THEQS------ESAHGRTGPSTGGRQRSRHEQARDSSRH---SASQEGQDTIRGHPG 1818
+ E A TG + GG + + D S +Q GQ ++ G PG
Sbjct: 963 NIPEEPILMTYELADETTGAAGGGLRGPEVDPGDDHSLEGLGEPAQAGQQSLEGDPG 1019
Score = 70.9 bits (172), Expect = 2e-11
Identities = 156/802 (19%), Positives = 284/802 (35%), Gaps = 145/802 (18%)
Query: 1516 GYHHSHTTPQGRSDASHGQSGPRSASRQTRNEEQSGDGSRHSGSRHHEPSTRAGSSRHSQ 1575
G H+ T + G GP + +E + G+GS+ R + +
Sbjct: 1711 GKTHTDPTSTRTVQGAEGGLGPGLSQGPGVDEGEDGEGSQ-----------RLNRDKDPK 1759
Query: 1576 VGQGESAGSKTSRRQGSSVSQDRDSEGHSEDSERRSESASRNHYGSAREQSRHGSRNPRS 1635
+G+ E G +++Q+R+ + H+ SE+++ + G A EQ G S
Sbjct: 1760 LGEAE----------GDAMAQEREGKTHN------SETSAGSELGEA-EQEGEGI----S 1798
Query: 1636 HQEDRASHGHSAESSRQSGTRHAETSSGGQAASSQEQARSSPGERHGSRHQQSADSSTDS 1695
+ + G E + Q G+AA+ +Q PG+ G+ ++ ++
Sbjct: 1799 ERGETGGQGSGHEDNLQ-----------GEAAAGGDQ---DPGQSDGAEGIEAPEAE--- 1841
Query: 1696 GTGRRQDSSVVGDSGNRGSSGSQASDSEGHSEESDTQSVSAHGQAGPHQQSHQESTRGQS 1755
G Q S G +A ++EG ++E A G+A P ES ++
Sbjct: 1842 --GEAQPE----------SEGVEAPEAEGDAQE-------AEGEAQP------ESEDVEA 1876
Query: 1756 GERSGRSGSFLYQVSTHEQSESAHGRTGPSTGGRQRSRHEQARDSSRHSASQEGQDTIRG 1815
E G + V T E A P + G + E +++ + S E +T
Sbjct: 1877 PEAEGEAQPESEDVETPE----AEWEVQPESEGAEAP--EAEKEAQPETESVEALETEGE 1930
Query: 1816 HPGSSRGGRQGSHYEQSVDSSGHSGSHHSHTTSQERSDVSRGQSGSRSVSRQTRNEKQSG 1875
S G E + ++ G + SQE + ++ +S + + E Q
Sbjct: 1931 DEPESEGAEAQEAEEAAQEAEGQTQPESEVIESQEAEEEAQPESEDVE-ALEVEVETQEA 1989
Query: 1876 DGSRHSGSRHHEASSRADSSRHSQVGQGQSSGPRTSRNQGSSVSQDSDSQGHSEDSERWS 1935
+G S EA + ++ + + P + + S+ ++Q ++++
Sbjct: 1990 EGEAQPESEDVEAPEAEGEMQEAE----EEAQPESDGVEAQPKSEGEEAQEVEGETQKTE 2045
Query: 1936 GSASRNHLGSAWEQSRDGSRHPGSHHEDRAGHGHSADSSRQSGTRHTESSSRGQAASSHE 1995
G A + DG P + E + G ++ G H ES
Sbjct: 2046 GDA---------QPESDGVEAPEAEEEAQEAEGEVQEA---EGEAHPESED--------V 2085
Query: 1996 QARSSAGERHGSHHQLQSADSSRHSGIGHGQASSAVRDSGHRGYSGSQASDSEGHS--ED 2053
A+ + GE +++ ++ G+A A G +A ++EG + E
Sbjct: 2086 DAQEAEGEAQPESEGVEAPEA-------EGEAQKA---------EGIEAPETEGEAQPES 2129
Query: 2054 SDTQSVSAQGKAGPHQQSHKESARGQSGESSGRSGSFLYQVSTHEQSESTHGQSAPSTGG 2113
++ A+G+A P +S A+ GE+ S Q + E G AP
Sbjct: 2130 EGIEAPEAEGEAQP--ESEGVEAQDAEGEAQPESEGIEAQEAEEEAQPELEGVEAPEA-- 2185
Query: 2114 RQGSHYDQAQDSSRHSASQEGQDTIRGHPGPSRGGRQGSHQEQSVDRSGHSG--SHHSHT 2171
+G +++ A E Q + G P + + + V+ G S
Sbjct: 2186 -EGEAQPESEGIEAPEAEGEAQPELEGVEAP-EAEEEAQPEPEGVETPEAEGEAQPESEG 2243
Query: 2172 TSQGRSDAS------RGQSGSRSASRKTYDKEQSGDGSRHSGSHHHE---ASSWADSSRH 2222
+QG S GQS S S +++ G H+ + + SSR
Sbjct: 2244 ETQGEKKGSPQVSLGDGQSEEASESSSPVPEDRPTPPPSPGGDTPHQRPGSQTGPSSSRA 2303
Query: 2223 SLVGQGQSSGPRTSRPRGSSVSQDSDSEGHSEDSERRSGSASRNHHGSAQEQSRDGSRHP 2282
S G G + S D+ S G + +ER++ S QE++ GSR P
Sbjct: 2304 SSWGNCWQKDSENDHVLGDTRSPDAKSTG-TPHAERKATRMYPESSTSEQEEAPLGSRTP 2362
Query: 2283 RSHHEDRAGHGHSAESSRQSGT 2304
E A G+ + + G+
Sbjct: 2363 ----EQGASEGYDLQEDQALGS 2380
Score = 70.5 bits (171), Expect = 3e-11
Identities = 236/1140 (20%), Positives = 384/1140 (33%), Gaps = 146/1140 (12%)
Query: 430 ENSDTQSVSGHGKAGLRQQSHQESTR-GRSGERSGRSGSSLYQVSTHEQPDSAHGRT--- 485
E S S GL + S ES+ R+ E S S Q+ + + G
Sbjct: 446 ERCSQDSASPASSTGLPEGSEPESSCCPRTPEDGVDSASPSAQIGAERKAGGSLGEDPGL 505
Query: 486 ---GTSTGGRQGSHHEQARDSSRHSASQEGQDTIRGHPGSSR-GGRQGSHHEQSVNRSGH 541
G GG + R S AS + + H GSS GGR G
Sbjct: 506 CIDGAGLGGPEQGGRLTPRARSEEGASSDSSASTGSHEGSSEWGGRP----------QGC 555
Query: 542 SGSHHSHTTSQGRSDASHGQSGSRSASRQTRNE---EQSGDGTRHSGSRHHEASSQADSS 598
G + T+ Q S+ S + S S ++ E G GT +
Sbjct: 556 PGKARAETSQQEASEGGDPASPALSLSSLRSDDLQAETQGQGTEQATGAAVTREPLVLGL 615
Query: 599 RHSQVGQGQSSGPRTSRNQGSSVSQDSDSQGHSEDSERWSGSASRNHHGSAQEQSRDGSR 658
S +G SS P T S QG R S +S + G + R
Sbjct: 616 SCSWDSEGASSTPSTC---------TSSQQGQRRHRSRASAMSSPSSPGLGRVAPRG--- 663
Query: 659 HPRSHHEDRAGHGHSADSSRKSGTRHTQNSSSGQAASSHEQARSSAGERHGSRHQLQ--- 715
HPR H + H S K R + + Q S + SS+ R + L+
Sbjct: 664 HPRHSHYRKDTHSPLDSSVTKQVPRPPERRRACQDGSVPRYSGSSSSTRTQASGNLRPPS 723
Query: 716 --SADSSRHSGTGHGQASSAVRDSGHRGSSGSQATDSEGHSEDSDTQSVSGHGQAGHHQQ 773
S S GT + AV G S A S G + D+ +++ S H
Sbjct: 724 SGSLPSQDLLGTSSATVTPAVHSDFVSGVSPHNA-PSAGWAGDAGSRTCSPAPIPPHTSD 782
Query: 774 SHQESARDRSGERSR----RSGSFLYQVSTHKQS----ESSHGWTGPSTGVRQGSHHEQA 825
S +S GE +R S + QV +Q SH + P T Q E
Sbjct: 783 SCSKSGAASLGEEARDTPQPSSPLVLQVGRPEQGAVGPHRSHCCSQPGTQPAQ----EAQ 838
Query: 826 RDNSRHSASQDGQ---DTIRGHPGSSRR----GRQGSHHEQSVDRSGHSGSHHSHTTSQG 878
R S ++ G+ RG P RR G GS H+ + G GS T G
Sbjct: 839 RGPSPEASWLCGRYCPTPPRGRPCPQRRSSSCGSTGSSHQSTA--RGPGGSPQEGTRQPG 896
Query: 879 -------RSDASRGQSGSRSA-SRTTRNEEQSRDGSRHSGSRHHEASSHADISRHSQAGQ 930
S ASR S S+ A SR E+ R G G S + + R
Sbjct: 897 PTPSPGPNSGASRRSSASQGAGSRGLSEEKTLRSGGGPQGQEEASGVSPSSLPR------ 950
Query: 931 GQSEGSRTSRRQGSSVSQDSDSEGHSEDSERWSGSASRNHRGSAQEQSRHGSRHPRSHHE 990
S R ++ ++ + E ++ +G+A RG + P H
Sbjct: 951 --SSPEAVVREWLDNIPEEPILMTY-ELADETTGAAGGGLRGPEVD--------PGDDH- 998
Query: 991 DRAGHGHSADSSRQS--GTPHAETS-SGGQAASSHEQARSSPGERHGSRHQQSADSSRHS 1047
G G A + +QS G P + G SS +S G G+ + +++ +
Sbjct: 999 SLEGLGEPAQAGQQSLEGDPGQDPEPEGALLGSSDTGPQSGEGVPQGAAPEGVSEAPAEA 1058
Query: 1048 GIPRRQASSAVRDSGHWGSSGSQASDSEGHSEESDTQSVSGHGQDGPHQQSHQESARDWS 1107
G R+A + R S +A + +++ G Q P S E +R +
Sbjct: 1059 GAD-REAPAGCRVS-------LRALPGRVSASTQIMRALMGSKQGRP--SSVPEVSRPMA 1108
Query: 1108 GGRSGRSGSFIYQVSTHEQSESAHGRTRTSTGRRQGSHHEQARDSSRH--SASQEGQDTI 1165
S +G+ I +++ + E G + + +++ S+ G+D +
Sbjct: 1109 RRLSCSAGALITCLASLQLFEEDLGSPASKVRFKDSPRYQELLSISKDLWPGCDVGEDQL 1168
Query: 1166 RAHPGSRRGGRQGSHHEQSVDRSGHSGSHHSHTTSQGRSDASHGQSGSRSASRQTRKD-- 1223
+ G + + + D H+ + + TS D S G GS +S D
Sbjct: 1169 DS------GLWELTWSQALPDLGSHAMTENFTPTSSSGVDISSGSGGSGESSVPCAMDGT 1222
Query: 1224 --KQSGD-----GSRHSGSRHHEAASWADSSRHSQVGQEQSSGSRTSRHQGSSVSQDSDS 1276
Q + ++ SR +E+ ++ + ++ + +DS+
Sbjct: 1223 LVTQGTELPLKTSNQRPDSRTYESPGDLENQQQCCFPTFLNARACACATNEDEAERDSEE 1282
Query: 1277 ERHSDDSERLSGSASRNHHGSSREQSRDGSRHPGFHQEDRASHGHSADSSRQSGTHHTES 1336
+R S + E+L+ + + E++++G+ G +E + Q TE
Sbjct: 1283 QRASSNLEQLAENTVQEE--VQLEETKEGTEGEGLQEE-----------AVQLEETKTEE 1329
Query: 1337 SSHGQAVSSHEQARSSPGERHGSRHQQSADSSRHSGIGHRQAS---SAVRDSGHRGSSGS 1393
+ V E+ + + GE Q + G G ++ V++ G G
Sbjct: 1330 GLQEEGVQL-EETKETEGEGQQEEEAQLEEIEETGGEGLQEEGVQLEEVKEGPEGGLQGE 1388
Query: 1394 QVTNSEGHSEDSDTQSVSAHGQ-----AGPHQQSHKESARGQSGESSGRSRSFLYQVSSH 1448
+ EG E+ + S HGQ + P + +E Q E +GR+ + +
Sbjct: 1389 AL--EEGLKEEGLPEEGSVHGQELSEASSPDGKGSQEDDPVQE-EEAGRASASAEPCPAE 1445
Query: 1449 EQSESTH-----GQTAPSTGGRQGSRHEQARNSSRHSASQDGQDTIRGHPGSSRGGRQGS 1503
E T +T PS RQ + A+ GQ+ + P R S
Sbjct: 1446 GTEEPTEPPSHLSETDPSASERQSGSQLEPGLEKPPGATMMGQEHTQAQPTQGAAERSSS 1505
Score = 64.3 bits (155), Expect = 2e-09
Identities = 129/554 (23%), Positives = 186/554 (33%), Gaps = 93/554 (16%)
Query: 3250 GSRHPRSHHEDRAGHGHSADRSRQSGTRHAETSSGGQAASSHEQARSSPGERHGSRHQQS 3309
G PR+ E+ G S+D S +G+ + GG + + PG+ QQ
Sbjct: 519 GRLTPRARSEE----GASSDSSASTGSHEGSSEWGG-------RPQGCPGKARAETSQQE 567
Query: 3310 ADSSRHSGIPRGQASSAVRDSRHWGSSGSQASDSEGHSEESDTQSVSGHGQAGPHQQSHQ 3369
A G P A S S ++ D + ++ T+ +G
Sbjct: 568 AS---EGGDPASPALSL---------SSLRSDDLQAETQGQGTEQATG------------ 603
Query: 3370 ESARDRSGGRSGRSGSFLYQVSTHEQSESAHGRTRTSTGRRQGSHHEQARDSSRHSASQE 3429
+A R G S S+ SE A T T +QG ++R S+ S S
Sbjct: 604 -AAVTREPLVLGLSCSW--------DSEGASSTPSTCTSSQQGQRRHRSRASAMSSPSSP 654
Query: 3430 GQDTI--RGHPGSSR-RGRQGSHYEQSVDRSGHSGSHHSHTTSQGRSDASRGQSGSRSAS 3486
G + RGHP S R S + SV + G G S S + +
Sbjct: 655 GLGRVAPRGHPRHSHYRKDTHSPLDSSVTKQVPRPPERRRACQDGSVPRYSGSSSS-TRT 713
Query: 3487 RQTRNDEQSGDGSRHSWSHHHEASTQADSSRHSQSGQGQSAGPRTSR----NQGSSVSQD 3542
+ + N GS S +S + HS G S S + GS
Sbjct: 714 QASGNLRPPSSGSLPSQDLLGTSSATVTPAVHSDFVSGVSPHNAPSAGWAGDAGSRTCSP 773
Query: 3543 SDSQGHSEDSERWSGSASRNHRGSAQEQSRDGSRHPTSHHEDRAGHGHSAESSRQSGTHH 3602
+ H+ DS SG+AS Q E A H + Q GT
Sbjct: 774 APIPPHTSDSCSKSGAASLGEEARDTPQPSSPLVLQVGRPEQGAVGPHRSHCCSQPGTQP 833
Query: 3603 AENSSGGQAASSH----------------EQARSSAGERHGSHHQQSA----DSSRHSGI 3642
A+ + G + + Q RSS+ GS HQ +A S +
Sbjct: 834 AQEAQRGPSPEASWLCGRYCPTPPRGRPCPQRRSSSCGSTGSSHQSTARGPGGSPQEGTR 893
Query: 3643 GHGQASSAVRDSG-HRGSSGSQASDSEGHSEDSDTQSVSAHGQAGPHQQSHQESTRGRSA 3701
G S +SG R SS SQ + S G SE+ +S GP Q S
Sbjct: 894 QPGPTPSPGPNSGASRRSSASQGAGSRGLSEEKTLRS-----GGGPQGQEEASGVSPSSL 948
Query: 3702 GRSGRSG---SFLYQV------STHEQSESAHGRAGPSTGGRQGSRHEQARDSSRH---S 3749
RS +L + T+E ++ G AG GG +G + D S
Sbjct: 949 PRSSPEAVVREWLDNIPEEPILMTYELADETTGAAG---GGLRGPEVDPGDDHSLEGLGE 1005
Query: 3750 ASQEGQDTIRGHPG 3763
+Q GQ ++ G PG
Sbjct: 1006 PAQAGQQSLEGDPG 1019
Score = 64.3 bits (155), Expect = 2e-09
Identities = 147/798 (18%), Positives = 251/798 (31%), Gaps = 139/798 (17%)
Query: 451 QESTRGRSGERSGRSGSSLYQVSTHEQPDSAHGRTGTSTGGRQGSHHEQARDSSRHSASQ 510
Q+ + + GE + + + TH P TST QG+ S+
Sbjct: 1690 QQILQRKRGEHTDGEAAEVAPGKTHTDP--------TSTRTVQGAEGGLGPGLSQGPGVD 1741
Query: 511 EGQDTIRGHPGSSRGGRQGSHHEQSVNRSGHSGSHHSHTTSQGRSDASHGQSGSRSASRQ 570
EG+D GS R R ++ G +Q R +H + SA +
Sbjct: 1742 EGEDG----EGSQRLNR---------DKDPKLGEAEGDAMAQEREGKTH--NSETSAGSE 1786
Query: 571 TRNEEQSGDGTRHSGSRH-----HEASSQADSSRHSQVGQGQSSGP-------------- 611
EQ G+G G HE + Q +++ GQS G
Sbjct: 1787 LGEAEQEGEGISERGETGGQGSGHEDNLQGEAAAGGDQDPGQSDGAEGIEAPEAEGEAQP 1846
Query: 612 -----RTSRNQGSSVSQDSDSQGHSEDSERWSGSASRNHHGSAQEQSRDGSRHPRSHHED 666
+G + + ++Q SED E + G AQ +S D
Sbjct: 1847 ESEGVEAPEAEGDAQEAEGEAQPESEDVE------APEAEGEAQPESEDVETPEAEWEVQ 1900
Query: 667 RAGHGHSADSSRKSGTRHTQNSSSGQAASSHEQARSSAGERHGSRHQLQSADSSRHSGTG 726
G A + K T++ + + E A + Q A+ + G
Sbjct: 1901 PESEGAEAPEAEKEAQPETESVEALETEGEDEPESEGA--------EAQEAEEAAQEAEG 1952
Query: 727 HGQASSAVRDSGHRGSSGS-QATDSEGHSEDSDTQSVSGHGQ-----------AGHHQQS 774
Q S V +S ++ D E + +TQ G Q G Q++
Sbjct: 1953 QTQPESEVIESQEAEEEAQPESEDVEALEVEVETQEAEGEAQPESEDVEAPEAEGEMQEA 2012
Query: 775 HQESARDRSGERSRRSGSFLYQVSTHKQSESSHGWTGP-STGVRQGSHHEQARDNSRHSA 833
+E+ + G ++ +++ + G P S GV E+A++ A
Sbjct: 2013 EEEAQPESDGVEAQPKSEGEEAQEVEGETQKTEGDAQPESDGVEAPEAEEEAQE-----A 2067
Query: 834 SQDGQDTIRGHPGSSRRGRQGSHHEQSVDRSGHSGSHHSHTTSQGRSDASRGQSGSRSAS 893
+ Q+ +G H +S D + S+G +A + ++ A
Sbjct: 2068 EGEVQEA------------EGEAHPESEDVDAQEAEGEAQPESEG-VEAPEAEGEAQKAE 2114
Query: 894 RTTRNEEQSRDGSRHSGSRHHEASSHADISRHSQAGQGQSEGSRTSRRQGSSVSQDSDSE 953
E + G EA A Q +SEG +G + + E
Sbjct: 2115 GIEAPETEGEAQPESEGIEAPEAEGEA---------QPESEGVEAQDAEGEAQPESEGIE 2165
Query: 954 GHSEDSE---RWSGSASRNHRGSAQEQSRHGSRHPRSHHEDRAG-HGHSADSSRQSGTPH 1009
+ E G + G AQ +S G P + E + G A + + P
Sbjct: 2166 AQEAEEEAQPELEGVEAPEAEGEAQPES-EGIEAPEAEGEAQPELEGVEAPEAEEEAQPE 2224
Query: 1010 AE--TSSGGQAASSHEQARSSPGERHGSRHQQSADSSRHSGIPRRQASSAVRDSGHWGSS 1067
E + + + E + GE+ GS D
Sbjct: 2225 PEGVETPEAEGEAQPESEGETQGEKKGSPQVSLGD-----------------------GQ 2261
Query: 1068 GSQASDSEGHSEESDTQSVSGHGQDGPHQQSHQESARDWSGGRSGRSGSFIYQVSTHEQS 1127
+AS+S E G D PHQ+ + +G S R+ S+ ++
Sbjct: 2262 SEEASESSSPVPEDRPTPPPSPGGDTPHQRPGSQ-----TGPSSSRASSWGNCWQKDSEN 2316
Query: 1128 ESAHGRTRTSTGRRQGSHHEQARDSSRHSASQEGQDTIRAHPGSRRGGRQGSHHEQSVDR 1187
+ G TR+ + G+ H + + + + S + P R QG+ +
Sbjct: 2317 DHVLGDTRSPDAKSTGTPHAERKATRMYPESSTSEQ--EEAPLGSRTPEQGASEGYDLQE 2374
Query: 1188 SGHSGSHHSHTTSQGRSD 1205
GS + T + GR+D
Sbjct: 2375 DQALGS-LAPTEAVGRAD 2391
Score = 63.5 bits (153), Expect = 4e-09
Identities = 219/1043 (20%), Positives = 344/1043 (32%), Gaps = 175/1043 (16%)
Query: 255 KIYERSRSSDGKSS-SQVNRSRHENTSQVPLQESRTRKRRGSRVSQDRDSEGHSEDSERH 313
++ R+RS +G SS S + HE +S+ + + + SQ SEG S
Sbjct: 520 RLTPRARSEEGASSDSSASTGSHEGSSEWGGRPQGCPGKARAETSQQEASEGGDPASPAL 579
Query: 314 SGSASRNH------HGSAWEQSRDGS--RHPR------SHDEDRASHGHSADSSRQSGTR 359
S S+ R+ G EQ+ + R P S D + AS S +S Q G R
Sbjct: 580 SLSSLRSDDLQAETQGQGTEQATGAAVTREPLVLGLSCSWDSEGASSTPSTCTSSQQGQR 639
Query: 360 -HAETSSRGQTASSHEQARSSP-GERHGSGHQQSADSSRHSATG--------RGQASSAV 409
H +S + SS R +P G S +++ S S+ R +A
Sbjct: 640 RHRSRASAMSSPSSPGLGRVAPRGHPRHSHYRKDTHSPLDSSVTKQVPRPPERRRACQDG 699
Query: 410 SDRGHRGSSGSQASDSEGH-----SENSDTQSVSGHGKAGLRQQSHQESTRGRSGERSGR 464
S + GSS S + + G+ S + +Q + G A + H + G
Sbjct: 700 SVPRYSGSSSSTRTQASGNLRPPSSGSLPSQDLLGTSSATVTPAVHSDFVSG-------- 751
Query: 465 SGSSLYQVSTHEQPDSAH-GRTGTSTGGRQGSHHEQARDSSRHSASQEGQDTIRGHPGSS 523
VS H P + G G+ T + S+ A+ G++ SS
Sbjct: 752 -------VSPHNAPSAGWAGDAGSRTCSPAPIPPHTSDSCSKSGAASLGEEARDTPQPSS 804
Query: 524 RGGRQGSHHEQSVNRSGHSGSHHSHTTSQ-GRSDASHGQSG-SRSAS------------- 568
Q EQ G G H SH SQ G A Q G S AS
Sbjct: 805 PLVLQVGRPEQ-----GAVGPHRSHCCSQPGTQPAQEAQRGPSPEASWLCGRYCPTPPRG 859
Query: 569 ---RQTRNEEQSGDGTRHSGSRHHEASSQADSSRHSQVGQGQSSGPRTSRNQGSSVSQDS 625
Q R+ G+ H + S + +R Q G S GP + ++ SS SQ +
Sbjct: 860 RPCPQRRSSSCGSTGSSHQSTARGPGGSPQEGTR--QPGPTPSPGPNSGASRRSSASQGA 917
Query: 626 DSQGHSEDSERWSGSASRNHHGSAQEQSRDGSRHPRSHHEDRAGHGHSADSSRKSGTRHT 685
S+G SE+ SG + G + S PRS S
Sbjct: 918 GSRGLSEEKTLRSGGGPQ---GQEEASGVSPSSLPRS-------------SPEAVVREWL 961
Query: 686 QNSSSGQAASSHEQARSSAGERHGSRHQLQSADSSRHSGTGHGQASSAVRDSGHRGSSGS 745
N ++E A + G G + HS G G+ + A G + G
Sbjct: 962 DNIPEEPILMTYELADETTGAAGGGLRGPEVDPGDDHSLEGLGEPAQA----GQQSLEGD 1017
Query: 746 QATDSEGHSE---DSDTQSVSGHG-QAGHHQQSHQESARDRSGERSRRSGSFLYQVSTHK 801
D E SDT SG G G + E+ + +R +G + +
Sbjct: 1018 PGQDPEPEGALLGSSDTGPQSGEGVPQGAAPEGVSEAPAEAGADREAPAGCRVSLRALPG 1077
Query: 802 QSESSHGWTGPSTGVRQG---SHHEQARDNSRHSASQDGQ-----------DTIRGHPGS 847
+ +S G +QG S E +R +R + G + G P S
Sbjct: 1078 RVSASTQIMRALMGSKQGRPSSVPEVSRPMARRLSCSAGALITCLASLQLFEEDLGSPAS 1137
Query: 848 SRRGRQGSHHEQSV-------------------------------DRSGHSGSHHSHTTS 876
R + +++ + D H+ + + TS
Sbjct: 1138 KVRFKDSPRYQELLSISKDLWPGCDVGEDQLDSGLWELTWSQALPDLGSHAMTENFTPTS 1197
Query: 877 QGRSDASRGQSGSRSAS---------RTTRNEEQSRDGSRHSGSRHHEASSHADISRHSQ 927
D S G GS +S T E + ++ SR +E S D+ Q
Sbjct: 1198 SSGVDISSGSGGSGESSVPCAMDGTLVTQGTELPLKTSNQRPDSRTYE--SPGDLENQQQ 1255
Query: 928 AGQGQSEGSRTSRRQGSSVSQDSDSEGHSEDSERWSGSASRNHRGSAQEQSRHGSRHPRS 987
+ + R + + + ++E SE+ +R S + + + QE+ +
Sbjct: 1256 C----CFPTFLNARACACATNEDEAERDSEE-QRASSNLEQLAENTVQEEVQ-----LEE 1305
Query: 988 HHEDRAGHGHSADSSRQSGTPHAETSSGGQAASSH-EQARSSPGERHGSRHQQSADSSRH 1046
E G G ++ + T +T G Q E+ + + GE Q +
Sbjct: 1306 TKEGTEGEGLQEEAVQLEET---KTEEGLQEEGVQLEETKETEGEGQQEEEAQLEEIEET 1362
Query: 1047 SGIPRRQASSAVRDSGHWGSSGSQASD-SEGHSEESDTQSVSGHGQD-----GPHQQSHQ 1100
G ++ + + G Q EG EE + S HGQ+ P + Q
Sbjct: 1363 GGEGLQEEGVQLEEVKEGPEGGLQGEALEEGLKEEGLPEEGSVHGQELSEASSPDGKGSQ 1422
Query: 1101 ES--ARDWSGGRSGRSGSFIYQVSTHEQSE--SAHGRTRTSTGRRQGSHHEQARDSSRHS 1156
E ++ GR+ S T E +E S T S RQ +
Sbjct: 1423 EDDPVQEEEAGRASASAEPCPAEGTEEPTEPPSHLSETDPSASERQSGSQLEPGLEKPPG 1482
Query: 1157 ASQEGQDTIRAHPGSRRGGRQGS 1179
A+ GQ+ +A P R S
Sbjct: 1483 ATMMGQEHTQAQPTQGAAERSSS 1505
Score = 58.9 bits (141), Expect = 1e-07
Identities = 124/707 (17%), Positives = 233/707 (32%), Gaps = 104/707 (14%)
Query: 804 ESSHGWTGPSTGVRQGSHHEQARDNSRHSASQDGQDTIRGHP--GSSRRGRQGSHHEQSV 861
+ + G GP G+ QG ++ D +D G + + R+G H
Sbjct: 1724 QGAEGGLGP--GLSQGPGVDEGEDGEGSQRLNRDKDPKLGEAEGDAMAQEREGKTHNSET 1781
Query: 862 DRSGHSGSHHSHTTSQGRSDASRGQSGSRSASRTTRNEEQSRDGSRHSGSRHHEASSHAD 921
+GS +G + RG++G + GS H + EA++ D
Sbjct: 1782 S----AGSELGEAEQEGEGISERGETGGQ--------------GSGHEDNLQGEAAAGGD 1823
Query: 922 ISRHSQAGQGQSEGSRTSRRQGSSVSQDSDSEGHSEDSERWSGSASRNHRGSAQEQSRHG 981
GQS+G+ + ++EG ++ G + G AQE G
Sbjct: 1824 ------QDPGQSDGAEG--------IEAPEAEGEAQPES--EGVEAPEAEGDAQE--AEG 1865
Query: 982 SRHPRSHH-EDRAGHGHSADSSRQSGTPHAE-----TSSGGQAASSHEQAR--------- 1026
P S E G + S TP AE S G +A + ++A+
Sbjct: 1866 EAQPESEDVEAPEAEGEAQPESEDVETPEAEWEVQPESEGAEAPEAEKEAQPETESVEAL 1925
Query: 1027 ----SSPGERHGSRHQQSADSSRHSGIPRRQASSAVRDSGHWGSSGSQASDSEGHSEESD 1082
E G+ Q++ ++++ + + S + + ++ D E E +
Sbjct: 1926 ETEGEDEPESEGAEAQEAEEAAQEAEGQTQPESEVIESQEAEEEAQPESEDVEALEVEVE 1985
Query: 1083 TQSVSGHGQ------DGPHQQSHQESARDWSGGRSGRSGSFIYQVSTHEQSESAHGRTRT 1136
TQ G Q + P + + A + + S G S E+++ G T+
Sbjct: 1986 TQEAEGEAQPESEDVEAPEAEGEMQEAEEEAQPES--DGVEAQPKSEGEEAQEVEGETQK 2043
Query: 1137 STGRRQ----GSHHEQARDSSRHSASQEGQDTIRAHPGSRRGGRQGSHHEQSVDRSGHSG 1192
+ G Q G +A + ++ + + + AHP S Q + E + G
Sbjct: 2044 TEGDAQPESDGVEAPEAEEEAQEAEGEVQEAEGEAHPESEDVDAQEAEGEAQPESEGVEA 2103
Query: 1193 SHHSHTTSQGRS-DASHGQSGSRSASRQTRKDKQSGDGSRHS-GSRHHEAASWADSSRHS 1250
+ +A + ++ S + G+ S G +A A
Sbjct: 2104 PEAEGEAQKAEGIEAPETEGEAQPESEGIEAPEAEGEAQPESEGVEAQDAEGEAQPESEG 2163
Query: 1251 QVGQEQSSGSRTSRHQGSSVSQDSDSERHSD--DSERLSGSASRNHHGSSREQSRDGSRH 1308
QE ++ + + +++ S+ ++ G A G ++ + ++
Sbjct: 2164 IEAQEAEEEAQPELEGVEAPEAEGEAQPESEGIEAPEAEGEAQPELEGVEAPEAEEEAQP 2223
Query: 1309 PGFHQEDRASHGHSADSSRQSGTHHTESS-----SHGQAVSSHEQARSSPGERHGSRHQQ 1363
E + G + S + S GQ+ + E + P +R
Sbjct: 2224 EPEGVETPEAEGEAQPESEGETQGEKKGSPQVSLGDGQSEEASESSSPVPEDRPTPPPSP 2283
Query: 1364 SADSSRHSGIGHRQASSAVRDSGHRGSSGSQVTNSEGHSED--SDTQSVSAHGQAGPHQQ 1421
D+ H++ S S R SS + ++ DT+S A PH +
Sbjct: 2284 GGDTP------HQRPGSQTGPSSSRASSWGNCWQKDSENDHVLGDTRSPDAKSTGTPHAE 2337
Query: 1422 SHKESARGQSGESSGRSRSFLY-QVSSHEQSESTHGQTAPSTGGRQG 1467
R + +Y + S+ EQ E+ G P G +G
Sbjct: 2338 ---------------RKATRMYPESSTSEQEEAPLGSRTPEQGASEG 2369
Score = 55.5 bits (132), Expect = 1e-06
Identities = 130/617 (21%), Positives = 191/617 (30%), Gaps = 68/617 (11%)
Query: 3267 SADRSRQSGTRHAETSSGGQAASSHEQARSSPGERHGSRHQQSADSSRHSGIPRGQASSA 3326
SA S Q G S G+ G G R A S + ++ +
Sbjct: 482 SASPSAQIGAERKAGGSLGEDPGLCIDGAGLGGPEQGGRLTPRARSEEGASSDSSASTGS 541
Query: 3327 VRDSRHWGSSGSQASDSEGHSEESDTQSVSGHGQAGPH-----------QQSHQESARDR 3375
S WG Q + +E S ++ G A P Q Q ++
Sbjct: 542 HEGSSEWGGR-PQGCPGKARAETSQQEASEGGDPASPALSLSSLRSDDLQAETQGQGTEQ 600
Query: 3376 SGGRSGRSGSFLYQVSTHEQSESAHGRTRTSTGRRQGSHHEQARDSSRHSASQEGQDTI- 3434
+ G + + +S SE A T T +QG ++R S+ S S G +
Sbjct: 601 ATGAAVTREPLVLGLSCSWDSEGASSTPSTCTSSQQGQRRHRSRASAMSSPSSPGLGRVA 660
Query: 3435 -RGHPGSSR-RGRQGSHYEQSVDRSGHSGSHHSHTTSQGRSDASRGQSGSRSASRQTRND 3492
RGHP S R S + SV + G G S S + ++ + N
Sbjct: 661 PRGHPRHSHYRKDTHSPLDSSVTKQVPRPPERRRACQDGSVPRYSGSSSS-TRTQASGNL 719
Query: 3493 EQSGDGSRHSWSHHHEASTQADSSRHSQSGQGQSAGPRTSR----NQGSSVSQDSDSQGH 3548
GS S +S + HS G S S + GS + H
Sbjct: 720 RPPSSGSLPSQDLLGTSSATVTPAVHSDFVSGVSPHNAPSAGWAGDAGSRTCSPAPIPPH 779
Query: 3549 SEDSERWSGSASRNHRGSAQEQSRDGSRHPTSHHEDRAGHGHSAESSRQSGTHHAENSSG 3608
+ DS SG+AS Q E A H + Q GT A+ +
Sbjct: 780 TSDSCSKSGAASLGEEARDTPQPSSPLVLQVGRPEQGAVGPHRSHCCSQPGTQPAQEAQR 839
Query: 3609 GQAA-SSHEQARSSAGERHGSHHQQSADSSRHSGIGHGQASSAVRDSGHRGSSGSQASDS 3667
G + +S R G Q SS G GSS +
Sbjct: 840 GPSPEASWLCGRYCPTPPRGRPCPQRRSSS----------------CGSTGSSHQSTARG 883
Query: 3668 EGHSEDSDTQSVSAHGQAGPHQQSHQESTRGRSAGRSGRSGSFLYQVSTHEQSESAHGRA 3727
G S T+ GP+ + + S+ + AG G S + Q +
Sbjct: 884 PGGSPQEGTRQPGPTPSPGPNSGASRRSSASQGAGSRGLSEEKTLRSGGGPQGQEEASGV 943
Query: 3728 GPSTGGRQGSRHEQARDSSRHSASQEGQDTIRGHP------------GSRRGGRQGSYHE 3775
PS+ R SS + +E D I P G+ GG +G +
Sbjct: 944 SPSSLPR----------SSPEAVVREWLDNIPEEPILMTYELADETTGAAGGGLRGPEVD 993
Query: 3776 QSVDRSGHSGSHHSHTTSQGRSDASHGQ----SGSRSASRETRNEEQSGDGSRHSGSRH- 3830
D S G Q + GQ G+ S +T QSG+G +
Sbjct: 994 PGDDHS-LEGLGEPAQAGQQSLEGDPGQDPEPEGALLGSSDT--GPQSGEGVPQGAAPEG 1050
Query: 3831 -HEASTQADSSRHSQSG 3846
EA +A + R + +G
Sbjct: 1051 VSEAPAEAGADREAPAG 1067
Score = 55.1 bits (131), Expect = 1e-06
Identities = 98/477 (20%), Positives = 154/477 (32%), Gaps = 62/477 (12%)
Query: 3504 SHHHEASTQADSSRHSQSGQGQSAGPRTSRNQGSSVSQDSD-SQGHSEDSERWSGSASRN 3562
+H ST+ G G S GP G +D + SQ + D + G A
Sbjct: 1713 THTDPTSTRTVQGAEGGLGPGLSQGP------GVDEGEDGEGSQRLNRDKDPKLGEA--- 1763
Query: 3563 HRGSAQEQSRDGSRHPTSHHEDRAGHGHSAESSRQSGTHHAENSSGGQAASSHEQARSSA 3622
G A Q R+G H G + Q G +E G S HE +
Sbjct: 1764 -EGDAMAQEREGKT-----HNSETSAGSELGEAEQEGEGISERGETGGQGSGHED--NLQ 1815
Query: 3623 GERHGSHHQQSADSSRHSGIGHGQASSAVRDSGHRGSSGSQASDSEGHSEDSDTQSVSAH 3682
GE Q S GI +A + S G +A ++EG +++ A
Sbjct: 1816 GEAAAGGDQDPGQSDGAEGIEAPEAEGEAQPE----SEGVEAPEAEGDAQE-------AE 1864
Query: 3683 GQAGPHQQSHQESTRGRSAGRSGRSGSFLYQVSTHEQSESAHGRAGPSTGGRQGSRHEQA 3742
G+A P ES + G + V T E A P + G + E
Sbjct: 1865 GEAQP------ESEDVEAPEAEGEAQPESEDVETPE----AEWEVQPESEGAEAP--EAE 1912
Query: 3743 RDSSRHSASQEGQDTIRGHPGSRRGGRQGSYHEQSVDRSGHSGSHHSHTTSQGRSDASHG 3802
+++ + S E +T G E + + G + SQ + +
Sbjct: 1913 KEAQPETESVEALETEGEDEPESEGAEAQEAEEAAQEAEGQTQPESEVIESQEAEEEAQP 1972
Query: 3803 QSGSRSASR-ETRNEEQSGDGSRHS--------GSRHHEASTQADSSRHSQSGQGESAGS 3853
+S A E +E G+ S EA +A Q +S G
Sbjct: 1973 ESEDVEALEVEVETQEAEGEAQPESEDVEAPEAEGEMQEAEEEAQPESDGVEAQPKSEGE 2032
Query: 3854 RRSRRQGSSVSQDSDSEAYPE-DSERRSESASRNHHGSSREQSRDGSRHPGSSHRDTASH 3912
+G +Q ++ +A PE D E+ Q +G HP S D
Sbjct: 2033 EAQEVEGE--TQKTEGDAQPESDGVEAPEAEEEAQEAEGEVQEAEGEAHPESEDVDAQEA 2090
Query: 3913 VQSSPVQSDSSTAKEHGHFSSLSQDSAYHSGIQSRGSPHSSSSYHYQSEGTERQKGQ 3969
+ +S+ A E ++ GI+ +P + +SEG E + +
Sbjct: 2091 EGEAQPESEGVEAPE------AEGEAQKAEGIE---APETEGEAQPESEGIEAPEAE 2138
Score = 54.7 bits (130), Expect = 2e-06
Identities = 136/720 (18%), Positives = 230/720 (31%), Gaps = 110/720 (15%)
Query: 3274 SGTRHAETSSGGQAASSHEQARSSPGERHGSRHQQSADSSRHSGIPRGQASSAVRDSRHW 3333
+ TR + + GG + GE + + D G G A + R+ +
Sbjct: 1718 TSTRTVQGAEGGLGPGLSQGPGVDEGEDGEGSQRLNRDKDPKLGEAEGDAMAQEREGKTH 1777
Query: 3334 GSSGSQASDSEGHSEESDTQSVSGHGQAGPHQQSHQESAR-------DRSGGRS-GRSGS 3385
S S + SE E + + +S G+ G H+++ + D+ G+S G G
Sbjct: 1778 NSETS--AGSELGEAEQEGEGISERGETGGQGSGHEDNLQGEAAAGGDQDPGQSDGAEGI 1835
Query: 3386 FLYQVSTHEQSESAHGRTRTSTGRRQGSHHEQARDSSRHSASQEGQDTIRGHPGSSRRGR 3445
+ Q ES + G Q + E +S A +
Sbjct: 1836 EAPEAEGEAQPESEGVEAPEAEGDAQEAEGEAQPESEDVEAPEA---------------- 1879
Query: 3446 QGSHYEQSVDRSGHSGSHHSHTTSQGRSDASRGQSGSRSASRQTRNDEQSGDGSRHSWSH 3505
+G +S D S+G ++A + ++ + E G+ S
Sbjct: 1880 EGEAQPESEDVETPEAEWEVQPESEG-AEAPEAEKEAQPETESVEALETEGEDEPES--- 1935
Query: 3506 HHEASTQADSSRHSQSGQGQSAGPRTSRNQGSSVSQDSDSQGHSEDSERWSGSASRNHRG 3565
E + ++ +Q +GQ+ + S + ++Q SED E
Sbjct: 1936 --EGAEAQEAEEAAQEAEGQT---QPESEVIESQEAEEEAQPESEDVEALEVEV------ 1984
Query: 3566 SAQEQSRDGSRHPTSHHEDRAGHGHSAESSRQSGTHHAENSSGG---QAASSHEQARSSA 3622
+ Q +G P S + AE Q A+ S G Q S E+A+
Sbjct: 1985 --ETQEAEGEAQPESEDVEAP----EAEGEMQEAEEEAQPESDGVEAQPKSEGEEAQEVE 2038
Query: 3623 GERHGSHHQQSADSSRHSGIGHGQASSAVRDSGHRGSSGSQASDSEGHSEDSDTQSVSAH 3682
GE + +S G + + Q ++ E H E D + A
Sbjct: 2039 GETQKTEGDAQPESD-------GVEAPEAEEEAQEAEGEVQEAEGEAHPESEDVDAQEAE 2091
Query: 3683 GQAGPHQQSHQESTRGRSAGRSGRSGSFLYQVSTHEQSES-------AHGRAGPSTGG-- 3733
G+A P + + A ++ G + Q ES A G A P + G
Sbjct: 2092 GEAQPESEGVEAPEAEGEAQKA--EGIEAPETEGEAQPESEGIEAPEAEGEAQPESEGVE 2149
Query: 3734 ---RQGSRHEQARDSSRHSASQEGQDTIRGHPGSRRGGRQGSYHEQSVDRSGHSGSHHSH 3790
+G ++ A +E Q + G G E + G
Sbjct: 2150 AQDAEGEAQPESEGIEAQEAEEEAQPELEGVEAPEAEG------EAQPESEGIEAPE--- 2200
Query: 3791 TTSQGRSDASHGQSGSRSASRETRNEEQSGDGSRHSGSRHHEASTQADSSRHSQSGQGES 3850
++G + + A E + E + + G E+ + QGE
Sbjct: 2201 --AEGEAQPELEGVEAPEAEEEAQPEPEGVETPEAEGEAQPESEGET---------QGEK 2249
Query: 3851 AGSRR-SRRQGSSVSQDSDSEAYPEDSERRSESASRNHHGSSREQSRDGSRHPGSSHRDT 3909
GS + S G S S PED S G R GS+ SS R +
Sbjct: 2250 KGSPQVSLGDGQSEEASESSSPVPEDRPTPPPSP-----GGDTPHQRPGSQTGPSSSRAS 2304
Query: 3910 ASHVQSSPVQSDSSTAKEHGHFSSLSQDSAYHSGIQSRGSPHS--SSSYHYQSEGTERQK 3967
+ + Q DS +H + S D+ +S G+PH+ ++ Y T Q+
Sbjct: 2305 S---WGNCWQKDSE--NDHVLGDTRSPDA------KSTGTPHAERKATRMYPESSTSEQE 2353
Score = 52.0 bits (123), Expect = 1e-05
Identities = 114/494 (23%), Positives = 175/494 (35%), Gaps = 58/494 (11%)
Query: 3503 WSHH---HEASTQADSSRHSQSGQGQSAGPRTS---RNQGSSVSQDSDSQGHSEDSERWS 3556
W H E +Q +S S +G + + P +S R V DS S +ER +
Sbjct: 438 WGHGTAGRERCSQDSASPASSTGLPEGSEPESSCCPRTPEDGV--DSASPSAQIGAERKA 495
Query: 3557 GSASRNHRGSAQEQSRDGSRHPTSHHEDRAG--HGHSAESSRQSGTHHAENSSGGQAASS 3614
G + G + + G RA G S++SS +G+H + GG+
Sbjct: 496 GGSLGEDPGLCIDGAGLGGPEQGGRLTPRARSEEGASSDSSASTGSHEGSSEWGGRPQGC 555
Query: 3615 HEQARSSAGERHGSHHQQSADSSRH-SGIGHGQASSAVRDSGHRGSSGSQAS-------- 3665
+AR+ ++ S A + S + + + G ++G+ +
Sbjct: 556 PGKARAETSQQEASEGGDPASPALSLSSLRSDDLQAETQGQGTEQATGAAVTREPLVLGL 615
Query: 3666 ----DSEGHSEDSDTQSVSAHGQAGPHQQSHQEST-----RGRSAGRSGRSGSFLYQVST 3716
DSEG S T + S GQ ++ S+ GR A R G Y+ T
Sbjct: 616 SCSWDSEGASSTPSTCTSSQQGQRRHRSRASAMSSPSSPGLGRVAPR-GHPRHSHYRKDT 674
Query: 3717 HEQSESAHGRAGPSTGGRQGSRHEQARDSSRHSASQEGQDTIRGHPGSRRGGRQGSYHEQ 3776
H +S+ + P R R +D S S T G+ R GS Q
Sbjct: 675 HSPLDSSVTKQVP----RPPERRRACQDGSVPRYSGSSSSTRTQASGNLRPPSSGSLPSQ 730
Query: 3777 --------SVDRSGHSGSHHSHTTSQGRSDASHGQSGSRSASRET----RNEEQSGDGSR 3824
+V + HS + S G +GSR+ S ++ S G+
Sbjct: 731 DLLGTSSATVTPAVHSDFVSGVSPHNAPSAGWAGDAGSRTCSPAPIPPHTSDSCSKSGAA 790
Query: 3825 HSGSRHHEASTQADSSRHSQSGQGE--SAGSRRSR---RQGSSVSQDSDSEAYPEDS--- 3876
G + + Q S Q G+ E + G RS + G+ +Q++ PE S
Sbjct: 791 SLGEEARD-TPQPSSPLVLQVGRPEQGAVGPHRSHCCSQPGTQPAQEAQRGPSPEASWLC 849
Query: 3877 ERRSESASRNHHGSSREQSRDGSRHPGSSHRDTASHVQSSPVQS--DSSTAKEHGHFSSL 3934
R + R R S GS GSSH+ TA SP + G S
Sbjct: 850 GRYCPTPPRGRPCPQRRSSSCGS--TGSSHQSTARGPGGSPQEGTRQPGPTPSPGPNSGA 907
Query: 3935 SQDSAYHSGIQSRG 3948
S+ S+ G SRG
Sbjct: 908 SRRSSASQGAGSRG 921
Score = 49.3 bits (116), Expect = 8e-05
Identities = 97/395 (24%), Positives = 139/395 (35%), Gaps = 60/395 (15%)
Query: 3608 GGQAASSHE----QARSSAGERHGSHHQQS-ADSSRHSGI-GHGQASS--AVRDSGHRGS 3659
GGQ +E +S GER + + A R SG+ GHG A +DS S
Sbjct: 398 GGQPGPKYEIWTNPLHASQGERVAARKRWGLAQHVRCSGLWGHGTAGRERCSQDSASPAS 457
Query: 3660 SGSQASDSEGHSEDSDTQSVSAHGQAGPHQQSHQESTRGRSAGRSGRSGSFLYQVSTHEQ 3719
S SE S A P Q E G S G G +
Sbjct: 458 STGLPEGSEPESSCCPRTPEDGVDSASPSAQIGAERKAGGSLGED--PGLCI-------- 507
Query: 3720 SESAHGRAGPSTGGRQGSRHEQ----ARDSSRHSASQEGQDTIRGHPGSRRGGRQGSYHE 3775
G GP GGR R + DSS + S EG G P G + +
Sbjct: 508 --DGAGLGGPEQGGRLTPRARSEEGASSDSSASTGSHEGSSEWGGRPQGCPGKARAETSQ 565
Query: 3776 QSVDRSGHSGSHHSHTTSQGRSDASHGQS---GSRSASRETRNEEQSGDGSRHSGSRHHE 3832
Q G S + + S RSD ++ G+ A+ E G S
Sbjct: 566 QEASEGGDPASP-ALSLSSLRSDDLQAETQGQGTEQATGAAVTREPLVLGLSCSWDSEGA 624
Query: 3833 ASTQADSSRHSQSGQGESAGSRRSRRQGSSVSQDSDS-------EAYPEDSERRSESASR 3885
+ST + + Q G RR R + S++S S +P S R ++ S
Sbjct: 625 SSTPSTCTSSQQ-------GQRRHRSRASAMSSPSSPGLGRVAPRGHPRHSHYRKDTHSP 677
Query: 3886 NHHGSSREQSR---------DGS--RHPGSSHRDTASHVQSS----PVQSDSSTAKEHGH 3930
+++ R DGS R+ GSS +++ Q+S P S S +++
Sbjct: 678 LDSSVTKQVPRPPERRRACQDGSVPRYSGSS---SSTRTQASGNLRPPSSGSLPSQDLLG 734
Query: 3931 FSSLSQDSAYHSGIQSRGSPHSSSSYHYQSEGTER 3965
SS + A HS S SPH++ S + + R
Sbjct: 735 TSSATVTPAVHSDFVSGVSPHNAPSAGWAGDAGSR 769
Score = 33.9 bits (76), Expect = 3.4
Identities = 52/268 (19%), Positives = 90/268 (33%), Gaps = 38/268 (14%)
Query: 3717 HEQSESAHGRAGPSTGGRQGSRHEQARDSSRHSASQEGQDTIRGHPGSRRGGRQGSYHEQ 3776
H E+A G + +R Q + +G G G +GS
Sbjct: 1700 HTDGEAAEVAPGKTHTDPTSTRTVQGAEGGLGPGLSQGPGVDEGEDG------EGS-QRL 1752
Query: 3777 SVDRSGHSGSHHSHTTSQGRSDASHGQSGSRSASRETRNEEQSGDGSRHSGSRH-----H 3831
+ D+ G +Q R +H + SA E EQ G+G G H
Sbjct: 1753 NRDKDPKLGEAEGDAMAQEREGKTH--NSETSAGSELGEAEQEGEGISERGETGGQGSGH 1810
Query: 3832 EASTQADSSRHSQSGQGESAGSRRSRRQGSSVSQDSDSEAYPED---SERRSESASRNHH 3888
E + Q +++ G+S G+ + +++ EA PE +E ++
Sbjct: 1811 EDNLQGEAAAGGDQDPGQSDGAE------GIEAPEAEGEAQPESEGVEAPEAEGDAQEAE 1864
Query: 3889 GSSREQSRD-------GSRHPGSSHRDTASHVQSSPVQSDSSTAKEHGHFSSLSQDSAYH 3941
G ++ +S D G P S +T +S+ + A E + +S
Sbjct: 1865 GEAQPESEDVEAPEAEGEAQPESEDVETPEAEWEVQPESEGAEAPEAEKEAQPETESVEA 1924
Query: 3942 SGIQSRGSPHSSSSYHYQSEGTERQKGQ 3969
+ P +SEG E Q+ +
Sbjct: 1925 LETEGEDEP--------ESEGAEAQEAE 1944
>gi|50083281 KIAA1853 protein [Homo sapiens]
Length = 611
Score = 89.7 bits (221), Expect = 5e-17
Identities = 122/538 (22%), Positives = 184/538 (34%), Gaps = 58/538 (10%)
Query: 865 GHSGSHHSHTTSQGRSDASRGQSGSRSASRTTRNEEQSRDGS------RHSGSRHHEASS 918
GHS SH T +SRG+ + ++R R S S + S +H S
Sbjct: 91 GHSASHDKDLTPP---PSSRGKKKKKKSTRKKRRRSSSYSPSPVKKKKKKSSKKHKRRRS 147
Query: 919 HADISRHSQAG-QGQSEGSRTSRRQGSSVSQDSDSEGHSEDSERWSGSASRNHRGSAQEQ 977
+ RHS + + + + ++Q S + S H R S SR + +
Sbjct: 148 FSKKRRHSSSSPKSKRRDEKRHKKQSRSRPRKSHRHRHHRCPSRSQSSESR----PSSCE 203
Query: 978 SRHGSRHPRSHHEDRAGHGHSADSSRQSGTPHAETSSGGQAASSHEQARSSPGERHGSRH 1037
SRH R P + R H + +P A++S S+ G GS
Sbjct: 204 SRHRGRSPEEGQKSRRRHSRRCSKTLCKDSPEAQSSRPPSQPLQMLGYLSARGVITGSGS 263
Query: 1038 QQSADSSRHSGIPRRQASSAVRDSGHWGSSGSQASDSEGHSEESDTQSVSGHGQDGPHQQ 1097
+ S + + S DSG+ SS + T S GQ+
Sbjct: 264 AADLFTKTASPLTTSRGRSQEYDSGNDTSS----------PPSTQTSSARSRGQEKGSPS 313
Query: 1098 SHQESARDWSGGRSGRSGSFIYQVSTHEQSESAHGRTRTSTGRRQGSHHEQARDSSRHSA 1157
+R+ + G + SG+ S + + TS GR + +
Sbjct: 314 GGLSKSRELNSGNTSDSGNSFTTSSPQNKGAMLENLSPTSRGRESRGFQSPCLECAEVKK 373
Query: 1158 SQEGQDTIRAHP-------GSRRGGRQGSHHEQSVD-----RSGHSGSHHSHTTSQGRSD 1205
S T R+ P S R SH +S + R S S S S RS
Sbjct: 374 SSLVPSTARSSPMKGCSRSSSYASTRSSSHSSRSPNPRASPRYTQSRSTSSEKRSYSRSP 433
Query: 1206 ASHGQSGSRSASRQTRKDKQSGDGSRHSGSRHHEAASWADSSRHSQVGQEQSSGSRTSRH 1265
+ +SG RS ++ + ++S SR+S SR + S + SQ +E+ R R
Sbjct: 434 SYSSKSGKRSPPSRSSRSRRSPSYSRYSPSRERDPKY---SEKDSQ-QRERERARRRRRS 489
Query: 1266 QGSSVSQDSDSERHSD----------------DSERLSGSASRNHHGSSREQSRDGSRHP 1309
+ DS H + S SGS S S SR SR
Sbjct: 490 YSPMRKRRRDSPSHLEARRITSARKRPIPYYRPSPSSSGSLSSTSSWYSSSSSRSASR-- 547
Query: 1310 GFHQEDRASHGHSADSSRQSGTHHTESSSHGQAVSSHEQARSSPGERHGSRHQQSADS 1367
+ + S +R S + + S S G S ++RS R SR SADS
Sbjct: 548 SYSRSRSRSRSRRRSRTRTSSSSSSRSPSPGSRSRSRSRSRSRSRSRSQSRSYSSADS 605
Score = 82.8 bits (203), Expect = 6e-15
Identities = 121/515 (23%), Positives = 197/515 (38%), Gaps = 52/515 (10%)
Query: 258 ERSRSSDGKSSSQVNRSRHENTSQVPLQESRTRKRR---GSRVSQDRDSEGHSEDSERHS 314
++ R S S S V + + +++ + + S ++KRR S S+ RD + H + S
Sbjct: 118 KKRRRSSSYSPSPVKKKKKKSSKKHKRRRSFSKKRRHSSSSPKSKRRDEKRHKKQSRSRP 177
Query: 315 GSASRNHHGSAWEQSRDGSRHPRSHDEDRASHGHSADSSRQSGTRHAETSSRGQTASSHE 374
+ R+ H +S+ P S + G S + ++S RH+ S+ S E
Sbjct: 178 RKSHRHRHHRCPSRSQSSESRPSSCESRH--RGRSPEEGQKSRRRHSRRCSKTLCKDSPE 235
Query: 375 QARSSPGERHGSGHQQSADSSRHSATGRGQASSAVSDRGHRGSSGSQASDSEGHSENSDT 434
S P + S+R TG G A+ + + S + S G S+ D
Sbjct: 236 AQSSRPPSQ--PLQMLGYLSARGVITGSGSAADLFT------KTASPLTTSRGRSQEYD- 286
Query: 435 QSVSGHGKAGLRQQSHQESTRGRSGERSGRSG--SSLYQVSTHEQPDSAHGRTGTSTGGR 492
SG+ + + S R R E+ SG S ++++ DS + T TS+
Sbjct: 287 ---SGNDTSS-PPSTQTSSARSRGQEKGSPSGGLSKSRELNSGNTSDSGNSFT-TSSPQN 341
Query: 493 QGSHHEQARDSSRHSASQEGQDTIRGH---------PGSSRGGRQGSHHEQSVNRSGHSG 543
+G+ E +SR S+ Q P ++R S S S
Sbjct: 342 KGAMLENLSPTSRGRESRGFQSPCLECAEVKKSSLVPSTARSSPMKGCSRSSSYASTRSS 401
Query: 544 SHHSHTTSQGRSDASHGQSGSRSASRQTRNEEQSGDGTRHSGSRHHEASSQADSSRHSQV 603
SH S + + AS + SRS S + R+ +S + SG R S++ SR S
Sbjct: 402 SHSSRSPNPR---ASPRYTQSRSTSSEKRSYSRSPSYSSKSGKR--SPPSRSSRSRRS-- 454
Query: 604 GQGQSSGPRTSRNQGSSVSQDSDSQGHSEDSERWSGSASRNHHGSAQEQSRDGSRHPRSH 663
P SR S S+ S+ ER R + +++ RD H +
Sbjct: 455 -------PSYSRYSPSRERDPKYSEKDSQQRERERARRRRRSYSPMRKRRRDSPSHLEAR 507
Query: 664 HEDRAGH--------GHSADSSRKSGTRHTQNSSSGQAASSHEQARSSAGERHGSRHQLQ 715
A S+ S S + +SSS A+ S+ ++RS + R SR +
Sbjct: 508 RITSARKRPIPYYRPSPSSSGSLSSTSSWYSSSSSRSASRSYSRSRSRSRSRRRSRTRTS 567
Query: 716 SADSSRHSGTGHGQASSAVRDSGHRGSSGSQATDS 750
S+ SSR G S + S R S S++ S
Sbjct: 568 SSSSSRSPSPGSRSRSRSRSRSRSRSRSQSRSYSS 602
Score = 82.0 bits (201), Expect = 1e-14
Identities = 122/537 (22%), Positives = 183/537 (34%), Gaps = 56/537 (10%)
Query: 2810 GHSGSHHSHTTSQGRSDASRGQSGSRSASRTTRNEEQSGDGS------RHSGSRHHEAST 2863
GHS SH T +SRG+ + ++R R S S + S +H +
Sbjct: 91 GHSASHDKDLTP---PPSSRGKKKKKKSTRKKRRRSSSYSPSPVKKKKKKSSKKHKRRRS 147
Query: 2864 HADISRH-SQAVQGQSEGSRRSRRQGSSVSQDSDSEGHSEDSERWSGSASRNHHGSAQEQ 2922
+ RH S + + + +R ++Q S + S H R S SR + +
Sbjct: 148 FSKKRRHSSSSPKSKRRDEKRHKKQSRSRPRKSHRHRHHRCPSRSQSSESR----PSSCE 203
Query: 2923 LRDGSRHPRSHQEDRAGHGHSADSSRQSGTRHTQTSSGGQAASSHEQARSSAGERHGSHH 2982
R R P Q+ R H + + Q+S S+ G GS
Sbjct: 204 SRHRGRSPEEGQKSRRRHSRRCSKTLCKDSPEAQSSRPPSQPLQMLGYLSARGVITGSGS 263
Query: 2983 QQSADSSRHSGIGHGQASSAVRDSGHRGYSGSQASDNEGHSEDSDTQSVSAHGQAGSHQQ 3042
+ S + + S DSG+ S + S + S S
Sbjct: 264 AADLFTKTASPLTTSRGRSQEYDSGNDTSSPPSTQTSSARSRGQEKGSPSGGLSKSRELN 323
Query: 3043 SHQESARGRSGETSG--HSGSFLYQVSTHEQSESSHGWTGPSTRGRQGSRHEQAQDSSRH 3100
S S G S TS + G+ L +S + S G+ P + + ++R
Sbjct: 324 SGNTSDSGNSFTTSSPQNKGAMLENLSPTSRGRESRGFQSPCLECAEVKKSSLVPSTARS 383
Query: 3101 S-------ASQYGQDTIRGHPGSSRGGRQGYHHEHSVDSSGHSGSHHSHTTSQGRSDASR 3153
S +S Y H S R + S +S S S RS +
Sbjct: 384 SPMKGCSRSSSYASTRSSSHSSRSPNPRASPRYTQSRSTS-------SEKRSYSRSPSYS 436
Query: 3154 GQSGSRSASRTTRNEEQSGDSSRHSVSRHHEASTHADISRHSQAVQGQSEGSRRSRRQGS 3213
+SG RS + +S SR+S SR + S+ Q + E +RR RR S
Sbjct: 437 SKSGKRSPPSRSSRSRRSPSYSRYSPSRERDPKYSEKDSQ-----QRERERARRRRRSYS 491
Query: 3214 SV-SQDSDSEGHSE----------------DSERWSGSASRNHRGSVQEQSRHGSR-HPR 3255
+ + DS H E S SGS S SR SR + R
Sbjct: 492 PMRKRRRDSPSHLEARRITSARKRPIPYYRPSPSSSGSLSSTSSWYSSSSSRSASRSYSR 551
Query: 3256 SHHEDRAGHGHSADRSRQSGTRHAETSSGGQAASSHEQARSSPGERHGSRHQQSADS 3312
S R+ R+R S + + + S G + S ++RS R SR SADS
Sbjct: 552 SRSRSRS---RRRSRTRTSSSSSSRSPSPGSRSRSRSRSRSRSRSRSQSRSYSSADS 605
Score = 78.6 bits (192), Expect = 1e-13
Identities = 128/553 (23%), Positives = 190/553 (34%), Gaps = 59/553 (10%)
Query: 1513 GHSGYHHSHTTPQGRSDASHGQSGPRSASRQTRNEEQSGDGS------RHSGSRHHEPST 1566
GHS H TP +S G+ + ++R+ R S S + S +H +
Sbjct: 91 GHSASHDKDLTPP---PSSRGKKKKKKSTRKKRRRSSSYSPSPVKKKKKKSSKKHKRRRS 147
Query: 1567 RAGSSRHSQVGQGESAGSKTSRRQGSSVSQDRDSEGHSEDSERRSESASRNHYGSARE-- 1624
+ RHS S+ K+ RR + S R SR+ +R
Sbjct: 148 FSKKRRHS------SSSPKSKRRDEKRHKKQSRSRPRKSHRHRHHRCPSRSQSSESRPSS 201
Query: 1625 -QSRHGSRNPRSHQEDRASHGHSAESSRQSGTRHAETSSGGQAASSQEQARSSPGERHGS 1683
+SRH R+P Q+ R H + + A++S S+ G GS
Sbjct: 202 CESRHRGRSPEEGQKSRRRHSRRCSKTLCKDSPEAQSSRPPSQPLQMLGYLSARGVITGS 261
Query: 1684 RHQQSADSSTDSGTGRRQDSSVVGDSGNRGSSGSQASDSEGHSEESDTQSVSAHGQAGPH 1743
+ T S + S DSGN SS S S + S S
Sbjct: 262 GSAADLFTKTASPLTTSRGRSQEYDSGNDTSSPPSTQTSSARSRGQEKGSPSG------- 314
Query: 1744 QQSHQESTRGQSGERSGRSGSFLYQVSTHEQSESAHGRTGPSTGGRQ-RSRHEQARDSSR 1802
+S SG S SF S+ + + P++ GR+ R + +
Sbjct: 315 --GLSKSRELNSGNTSDSGNSFT--TSSPQNKGAMLENLSPTSRGRESRGFQSPCLECAE 370
Query: 1803 HSASQEGQDTIRGHPGSSRGGRQGSHYEQSVDSSGHSGSHHSHTTSQERSDVSRGQSGSR 1862
S T R P +G + S Y +S S SH S + + S + SR
Sbjct: 371 VKKSSLVPSTARSSP--MKGCSRSSSY-----ASTRSSSHSSRSPNPRASP---RYTQSR 420
Query: 1863 SVSRQTRNEKQSGDGSRHSGSRHHEASSRADSSRHSQVGQGQSSGPRTSRNQGSSVSQDS 1922
S S + R+ +S S SG R SR+ SR S P SR S
Sbjct: 421 STSSEKRSYSRSPSYSSKSGKR--SPPSRSSRSRRS---------PSYSRYSPSRERDPK 469
Query: 1923 DSQGHSEDSERWSGSASRNHLGSAWEQSRDGSRHPGSHHEDRAGH--------GHSADSS 1974
S+ S+ ER R ++ RD H + A S+ S
Sbjct: 470 YSEKDSQQRERERARRRRRSYSPMRKRRRDSPSHLEARRITSARKRPIPYYRPSPSSSGS 529
Query: 1975 RQSGTRHTESSSRGQAASSHEQARSSAGERHGSHHQLQSADSSRHSGIGHGQASSAVRDS 2034
S + SSS A+ S+ ++RS + R S + S+ SSR G S + S
Sbjct: 530 LSSTSSWYSSSSSRSASRSYSRSRSRSRSRRRSRTRTSSSSSSRSPSPGSRSRSRSRSRS 589
Query: 2035 GHRGYSGSQASDS 2047
R S S++ S
Sbjct: 590 RSRSRSQSRSYSS 602
Score = 74.7 bits (182), Expect = 2e-12
Identities = 128/550 (23%), Positives = 189/550 (34%), Gaps = 82/550 (14%)
Query: 2162 GHSGSHHSHTTSQGRSDASRGQSGSRSASRKTYDKEQSGDGS------RHSGSHHHEASS 2215
GHS SH T +SRG+ + ++RK + S S + S H S
Sbjct: 91 GHSASHDKDLTPP---PSSRGKKKKKKSTRKKRRRSSSYSPSPVKKKKKKSSKKHKRRRS 147
Query: 2216 WADSSRHSLVGQGQSSGPRT-------------SRPRGSSVSQDSDSEGHSEDSERRSGS 2262
++ RHS SS P++ SRPR S + S+ SE R S
Sbjct: 148 FSKKRRHS------SSSPKSKRRDEKRHKKQSRSRPRKSHRHRHHRCPSRSQSSESRPSS 201
Query: 2263 ASRNHHG-SAQEQSRDGSRHPRSHHEDRAGHGHSAESSR-------QSGTHHAENSSGGQ 2314
H G S +E + RH R + A+SSR G A G
Sbjct: 202 CESRHRGRSPEEGQKSRRRHSRRCSKTLCKDSPEAQSSRPPSQPLQMLGYLSARGVITGS 261
Query: 2315 AASSHEQARSSAGERHGSHHQQSADSSRHSGIGHGQASSAVRDSG-HRGSSGSQASDSEG 2373
+++ ++++ Q DS + +S+ R G +GS S S
Sbjct: 262 GSAADLFTKTASPLTTSRGRSQEYDSGNDTSSPPSTQTSSARSRGQEKGSPSGGLSKSRE 321
Query: 2374 HSEDSDTQSVSAHGQAGPHQQSHQ-ESTRGRSAGRSGRSGSFLYQVSTHEQSESAHGRTG 2432
+ + + S ++ + P + E+ S GR R +Q E +E
Sbjct: 322 LNSGNTSDSGNSFTTSSPQNKGAMLENLSPTSRGRESRG----FQSPCLECAEVKKSSLV 377
Query: 2433 TSTGGRQGSHHKQARDSSRHSTSQEGQDTIHGHPGSSSGGRQGSHYEQLVDRSGHSGSHH 2492
ST R +R SS ST H S R Y Q S S
Sbjct: 378 PST-ARSSPMKGCSRSSSYASTRSS------SHSSRSPNPRASPRYTQ-------SRSTS 423
Query: 2493 SHTTSQGRSDASHGHSGSRSASRQTRNDEQSGDGSRHSGSRHHEAS-SRADSSGHSQVGQ 2551
S S RS + SG RS ++ +S SR+S SR + S DS
Sbjct: 424 SEKRSYSRSPSYSSKSGKRSPPSRSSRSRRSPSYSRYSPSRERDPKYSEKDSQQRE---- 479
Query: 2552 GQSEGPRTSRNWGSSFSQDSDSQGHSE----------------DSERWSGSASRNHHGSA 2595
+ R R++ + DS H E S SGS S +
Sbjct: 480 -RERARRRRRSYSPMRKRRRDSPSHLEARRITSARKRPIPYYRPSPSSSGSLSSTSSWYS 538
Query: 2596 QEQLRDGSR-HPRSHQEDRAGHGHSADSSRQSGTRHTQTSSGGQAASSHEQARSSAGERH 2654
R SR + RS R+ +R S + +++ S G + S ++RS + R
Sbjct: 539 SSSSRSASRSYSRSRSRSRS---RRRSRTRTSSSSSSRSPSPGSRSRSRSRSRSRSRSRS 595
Query: 2655 GSHHQQSADS 2664
S SADS
Sbjct: 596 QSRSYSSADS 605
Score = 73.2 bits (178), Expect = 5e-12
Identities = 116/529 (21%), Positives = 195/529 (36%), Gaps = 28/529 (5%)
Query: 439 GHGKAGLRQQSHQESTRGRSGERSGRSGSSLYQVSTHEQPDSAHGRTGTSTGGRQGSHHE 498
GH + + + S+RG+ ++ S P + + R+ S +
Sbjct: 91 GHSASHDKDLTPPPSSRGKKKKKKSTRKKRRRSSSYSPSPVKKKKKKSSKKHKRRRSFSK 150
Query: 499 QARDSSRHSASQEGQDTIRGHPGSSRGGRQGSH---HEQSVNRSGHSGSHHSHTTSQGRS 555
+ R SS S+ + + H SR + SH H + +RS S S S S+ R
Sbjct: 151 KRRHSSSSPKSKRRDE--KRHKKQSRSRPRKSHRHRHHRCPSRSQSSESRPSSCESRHRG 208
Query: 556 DA-SHGQSGSRSASRQTRNEEQSGDGTRHSGSRHHEASSQAD---SSRHSQVGQG----- 606
+ GQ R SR+ ++ D SR Q S+R G G
Sbjct: 209 RSPEEGQKSRRRHSRRC-SKTLCKDSPEAQSSRPPSQPLQMLGYLSARGVITGSGSAADL 267
Query: 607 --QSSGPRTSRNQGSSVSQDSDSQGHSEDSERWSGSASRNHHGSAQEQSRDGSRHPRSHH 664
+++ P T+ ++G S DS + S S + S + SR + SR S +
Sbjct: 268 FTKTASPLTT-SRGRSQEYDSGNDTSSPPSTQTSSARSRGQEKGSPSGGLSKSRELNSGN 326
Query: 665 EDRAGHGHSADSSRKSGT--RHTQNSSSGQAASSHEQARSSAGERHGSRHQLQSADSSRH 722
+G+ + S + G + +S G+ + + E S +A SS
Sbjct: 327 TSDSGNSFTTSSPQNKGAMLENLSPTSRGRESRGFQSPCLECAEVKKSSLVPSTARSSPM 386
Query: 723 SGTGHGQASSAVRDSGHRGSSGS-QATDSEGHSEDSDTQSVSGHGQAGHHQQSHQESARD 781
G + ++ R S H S + +A+ S + ++ S + +S + S
Sbjct: 387 KGCSRSSSYASTRSSSHSSRSPNPRASPRYTQSRSTSSEKRSYSRSPSYSSKSGKRSPPS 446
Query: 782 RSGERSRRSGSFLYQVSTHKQSESSHGWTGPSTGVRQGSHHEQARDNSRHSASQDGQDTI 841
RS RSRRS S+ + S ++ + + R+ + + + +D +
Sbjct: 447 RSS-RSRRSPSYS-RYSPSRERDPKYSEKDSQQRERERARRRRRSYSPMRKRRRDSPSHL 504
Query: 842 RGHPGSSRRGRQGSHHEQSVDRSGHSGSHHSHTTSQGRSDASRGQSGSRSASRTTRNEEQ 901
+S R R ++ S SG S S +S ASR S SRS SR+ R
Sbjct: 505 EARRITSARKRPIPYYRPSPSSSGSLSSTSSWYSSSSSRSASRSYSRSRSRSRSRR---- 560
Query: 902 SRDGSRHSGSRHHEASSHADISRHSQAGQGQSEGSRTSRRQGSSVSQDS 950
R +R S S + S SR + +S SR S+ S S
Sbjct: 561 -RSRTRTSSSSSSRSPSPGSRSRSRSRSRSRSRSRSQSRSYSSADSYSS 608
Score = 72.0 bits (175), Expect = 1e-11
Identities = 122/596 (20%), Positives = 207/596 (34%), Gaps = 93/596 (15%)
Query: 1327 RQSGTHHTESSSHGQAVSSHEQARSSPGERHGSRHQQSADSS----------RHSGIGHR 1376
R+ G S+SH + ++ +R ++ +R ++ SS + S H+
Sbjct: 84 RELGATRGHSASHDKDLTPPPSSRGKKKKKKSTRKKRRRSSSYSPSPVKKKKKKSSKKHK 143
Query: 1377 QASSAVRDSGHRGSSG-SQVTNSEGHSEDSDTQSVSAHGQAGPHQQSHKESARGQSGESS 1435
+ S + H SS S+ + + H + S ++ +H + H+ +R QS ES
Sbjct: 144 RRRSFSKKRRHSSSSPKSKRRDEKRHKKQSRSRPRKSH-----RHRHHRCPSRSQSSESR 198
Query: 1436 GRSRSFLYQVSSHEQSESTHGQTAPSTGGRQGSRHEQARNSSRHSASQDGQDTIRGHPGS 1495
S ES H +P G Q SR +R S+ + +D + P S
Sbjct: 199 PSS------------CESRHRGRSPEEG--QKSRRRHSRRCSK-TLCKDSPEAQSSRPPS 243
Query: 1496 SRGGRQGSYHEQSVDRSGHSGYHHSHTTPQGRSDASHGQSGPRSASRQTRNEEQSGDGSR 1555
Q + G+ T +D + P + SR E SG+ +
Sbjct: 244 -----------QPLQMLGYLSARGVITGSGSAADLFTKTASPLTTSRGRSQEYDSGNDTS 292
Query: 1556 HSGSRHHEPSTRAGSSRHSQVGQGESAGSKTSRRQGSSVSQDRDSEGHSEDSERRSESAS 1615
PST+ S+R +G +G + R+ +S + + S + +
Sbjct: 293 SP------PSTQTSSARSRGQEKGSPSGGLSKSRELNSGNTSDSGNSFTTSSPQNKGAML 346
Query: 1616 RNHYGSAREQSRHGSRNPRSHQEDRASHGHSAESSRQSGTRHAETSSGGQAASSQEQARS 1675
N ++R + G ++P + ++R S + SS + S +
Sbjct: 347 ENLSPTSRGRESRGFQSPCLECAEVKKSSLVPSTARSSPMKGCSRSSSYASTRSSSHSSR 406
Query: 1676 SPGERHGSRHQQSADSSTDSGTGRRQDSSVVGDSGNRGSSGSQASDSEGHSEESDTQSVS 1735
SP R R+ QS +S++ + R S +S +S
Sbjct: 407 SPNPRASPRYTQSRSTSSEKRSYSRSPS---------------------YSSKS------ 439
Query: 1736 AHGQAGPHQQSHQESTRGQSGERSGRSGSFLYQVSTHEQSESAHGRTGPSTGGRQRSRHE 1795
G+ P +S RS RS S+ + S + + + R+R+R
Sbjct: 440 --GKRSPPSRS----------SRSRRSPSYS-RYSPSRERDPKYSEKDSQQRERERARRR 486
Query: 1796 QARDSSRHSASQEGQDTIRGHPGSSRGGRQGSHYEQSVDSSGHSGSHHSHTTSQERSDVS 1855
+ S ++ + +S R +Y S SSG S S +S S
Sbjct: 487 RRSYSPMRKRRRDSPSHLEARRITSARKRPIPYYRPSPSSSGSLSSTSSWYSSSSSRSAS 546
Query: 1856 RGQSGSRSVSR-----QTRNEKQSGDGSRHSGSRHHEASSRADSSRHSQVGQGQSS 1906
R S SRS SR +TR S S GSR S SR + SS
Sbjct: 547 RSYSRSRSRSRSRRRSRTRTSSSSSSRSPSPGSRSRSRSRSRSRSRSRSQSRSYSS 602
Score = 71.2 bits (173), Expect = 2e-11
Identities = 127/539 (23%), Positives = 195/539 (36%), Gaps = 60/539 (11%)
Query: 2486 GHSGSHHSHTTSQGRSDASHGHSGSRSASRQTRNDEQSGDGSRHSGSRHHEASSRADSSG 2545
GHS SH T +S G + ++R+ R S S + +
Sbjct: 91 GHSASHDKDLTPP---PSSRGKKKKKKSTRKKRRRSSSYSPSPVKKKKKKSSKKHKRRRS 147
Query: 2546 HSQVGQGQSEGPRTSRNWGSSFSQDSDSQGHSEDSERWSGSASRNHHGSAQEQLRDGSRH 2605
S+ + S P++ R D + H + S + R+ H + +
Sbjct: 148 FSKKRRHSSSSPKSKRR---------DEKRHKKQSRSRPRKSHRHRHHRCPSRSQSSESR 198
Query: 2606 PRSHQEDRAGHGHSADSSRQSGTRHTQTSSGGQAASSHEQARSSAGERHGSHHQQSADSS 2665
P S + G S + ++S RH++ S S E A+SS R S Q
Sbjct: 199 PSSCESRH--RGRSPEEGQKSRRRHSRRCSKTLCKDSPE-AQSS---RPPSQPLQMLGYL 252
Query: 2666 RHSGI--GHGQASSAVRDSGH-----RGYSGSQASDNEGHSEDS-DTQSVSAHGQA-GSH 2716
G+ G G A+ + RG S S N+ S S T S + GQ GS
Sbjct: 253 SARGVITGSGSAADLFTKTASPLTTSRGRSQEYDSGNDTSSPPSTQTSSARSRGQEKGSP 312
Query: 2717 QQSHQESARGRSGETSGHSGSFLYQVSTHEQSESSHGWTGPSTRGRQGSRHEQ-AQDSSR 2775
+S SG TS SF S+ + + P++RGR+ + + +
Sbjct: 313 SGGLSKSRELNSGNTSDSGNSFT--TSSPQNKGAMLENLSPTSRGRESRGFQSPCLECAE 370
Query: 2776 HSASQDGQDTIRGHPGSSRGGRQGYHHEHSVDSSGHSGSHH-SHTTSQGRSDASRGQSGS 2834
S T R P Y S S S + S +Q RS +S +S S
Sbjct: 371 VKKSSLVPSTARSSPMKGCSRSSSYASTRSSSHSSRSPNPRASPRYTQSRSTSSEKRSYS 430
Query: 2835 RSASRTTRNEEQSGDGSRHSGSRHHEASTHADISRH-------SQAVQGQSEGSRRSRRQ 2887
RS S ++++ ++S SR S SR + + SR + Q + E +RR RR
Sbjct: 431 RSPSYSSKSGKRSPP-SRSSRSRRSPSYSRYSPSRERDPKYSEKDSQQRERERARRRRRS 489
Query: 2888 GSSV-SQDSDSEGHSE----------------DSERWSGSASRNHHGSAQEQLRDGSR-H 2929
S + + DS H E S SGS S + R SR +
Sbjct: 490 YSPMRKRRRDSPSHLEARRITSARKRPIPYYRPSPSSSGSLSSTSSWYSSSSSRSASRSY 549
Query: 2930 PRSHQEDRAGHGHSADSSRQSGTRHTQTSSGGQAASSHEQARSSAGERHGSHHQQSADS 2988
RS R+ +R S + +++ S G + S ++RS + R S SADS
Sbjct: 550 SRSRSRSRS---RRRSRTRTSSSSSSRSPSPGSRSRSRSRSRSRSRSRSQSRSYSSADS 605
Score = 70.9 bits (172), Expect = 2e-11
Identities = 120/525 (22%), Positives = 204/525 (38%), Gaps = 53/525 (10%)
Query: 3394 EQSESAHGRTRTSTGRRQGSHHEQARDSSRHSASQEGQDTIRGHPGSS---RRGRQGSHY 3450
++ +S + R S+ ++ + SS+ + R H SS +R + H
Sbjct: 111 KKKKSTRKKRRRSSSYSPSPVKKKKKKSSKKHKRRRSFSKKRRHSSSSPKSKRRDEKRHK 170
Query: 3451 EQSVDRSGHSGSHHSHTTSQGRSDASRGQSG-SRSASRQTRNDEQSGDGSRHSWSHHHEA 3509
+QS R S H H SR QS SR +S ++R+ +S + + S H
Sbjct: 171 KQSRSRPRKSHRHRHHRCP------SRSQSSESRPSSCESRHRGRSPEEGQKSRRRH--- 221
Query: 3510 STQADSSRHSQSGQGQSAGPRTSRNQGS---SVSQDSDSQGHSEDSERWSGSASRNHRGS 3566
S + + S + QS+ P + Q S G + D + S RG
Sbjct: 222 SRRCSKTLCKDSPEAQSSRPPSQPLQMLGYLSARGVITGSGSAADLFTKTASPLTTSRGR 281
Query: 3567 AQE--QSRDGSRHPTSHHEDRAGHGHSAESSRQSGTHHAENSSGGQAASSHEQARSSAGE 3624
+QE D S P++ G + S G + + G + S +S+ +
Sbjct: 282 SQEYDSGNDTSSPPSTQTSSARSRGQE-KGSPSGGLSKSRELNSGNTSDSGNSFTTSSPQ 340
Query: 3625 RHGSHHQQSADSSRHSGIGHGQASSAVRDSGHRGSS----GSQASDSEGHSEDSDTQSV- 3679
G+ + + +SR G S + + + SS +++S +G S S S
Sbjct: 341 NKGAMLENLSPTSRGRE-SRGFQSPCLECAEVKKSSLVPSTARSSPMKGCSRSSSYASTR 399
Query: 3680 -SAHGQAGPHQQSHQESTRGRSAGRSGRSGSFLYQVSTHEQSESAHGRAGPSTGGRQGSR 3738
S+H P+ ++ T+ RS RS + +S S ++G + + SR
Sbjct: 400 SSSHSSRSPNPRASPRYTQSRSTSSEKRS---------YSRSPSYSSKSGKRSPPSRSSR 450
Query: 3739 HEQARDSSRHSASQEGQDTIRGHPGSRRGGRQGSYHEQSVDRSGHSGSHHSHTTSQGRSD 3798
++ SR+S S+E R S + +Q + +R+ +S + R
Sbjct: 451 SRRSPSYSRYSPSRE-----RDPKYSEKDSQQ-----RERERARRRRRSYSPMRKRRRDS 500
Query: 3799 ASHGQSGSRSASRETR----NEEQSGDGSRHSGSRHHEASTQADSSRHSQSGQGESAGSR 3854
SH ++ +++R+ S GS S S + +S+ +SR + S R
Sbjct: 501 PSHLEARRITSARKRPIPYYRPSPSSSGSLSSTSSWYSSSSSRSASRSYSRSRSRSRSRR 560
Query: 3855 RSRRQGSSVSQDSDSEAYPEDSERRSESASRNHHGSSREQSRDGS 3899
RSR + SS S S S + S RS S SR+ SR QSR S
Sbjct: 561 RSRTRTSS-SSSSRSPSPGSRSRSRSRSRSRSR---SRSQSRSYS 601
Score = 68.2 bits (165), Expect = 2e-10
Identities = 131/576 (22%), Positives = 211/576 (36%), Gaps = 82/576 (14%)
Query: 1266 QGSSVSQDSD-SERHSDDSERLSGSASRNHHGSSREQSRDGSRHPGFHQEDRASHGHSAD 1324
+G S S D D + S ++ ++R R +S S P ++ ++S H
Sbjct: 90 RGHSASHDKDLTPPPSSRGKKKKKKSTRK----KRRRSSSYSPSPVKKKKKKSSKKHKRR 145
Query: 1325 SSRQSGTHHTESSSHGQAVSSH---EQARSSPGERHGSRHQQSADSSRHSGIGHRQASSA 1381
S H+ SS + +Q+RS P + H RH + S+ S ++ +
Sbjct: 146 RSFSKKRRHSSSSPKSKRRDEKRHKKQSRSRPRKSHRHRHHRCPSRSQSS-----ESRPS 200
Query: 1382 VRDSGHRGSSGSQVTNS-EGHSE-------DSDTQSVSAHGQAGPHQQSHKESARGQSGE 1433
+S HRG S + S HS ++ S+ + P Q SARG
Sbjct: 201 SCESRHRGRSPEEGQKSRRRHSRRCSKTLCKDSPEAQSSRPPSQPLQMLGYLSARGVITG 260
Query: 1434 SSGRSRSFLYQVSSHEQSESTHGQTAPSTGGRQGSRHEQARNSSRHSASQDGQDTIRGHP 1493
S + F S ++ G++ G S + SS S Q+
Sbjct: 261 SGSAADLFTKTAS---PLTTSRGRSQEYDSGNDTSSPPSTQTSSARSRGQE--------K 309
Query: 1494 GSSRGGRQGSYHEQSVDRSGHSGYHHSHTTPQGRSDASHGQSGPRSASRQTRNEEQSGDG 1553
GS GG S E + + SG + ++PQ + S P S R++R +
Sbjct: 310 GSPSGGLSKS-RELNSGNTSDSGNSFTTSSPQNKGAMLENLS-PTSRGRESRGFQSPCLE 367
Query: 1554 SRHSGSRHHEPST-----RAGSSRHSQVGQGESAGSKTSRRQGSSVSQDRDSEGHSEDSE 1608
PST G SR S S S S R + + R ++ S SE
Sbjct: 368 CAEVKKSSLVPSTARSSPMKGCSRSSSYASTRS--SSHSSRSPNPRASPRYTQSRSTSSE 425
Query: 1609 RRSESASRNHYGSAREQSRHGSRNPRSHQEDRASHGHSAES-SRQSGTRHAETSSGGQAA 1667
+RS S S ++ S+ G R+P S R+S + S SR S +R + + +
Sbjct: 426 KRSYSRSPSY------SSKSGKRSPPS----RSSRSRRSPSYSRYSPSRERDPKYSEKDS 475
Query: 1668 SSQEQARSSPGERHGSRHQQSADSSTDSGTGRRQDSS----VVGDSGNRGSSGSQASDSE 1723
+E+ R+ R S ++ S RR S+ + + SSGS +S S
Sbjct: 476 QQRERERARRRRRSYSPMRKRRRDSPSHLEARRITSARKRPIPYYRPSPSSSGSLSSTSS 535
Query: 1724 GHSEESDTQSVSAHGQAGPHQQSHQESTRGQSGERSGRSGSFLYQVSTHEQSESAHGRTG 1783
+S S + ++ ++ +S + S S S RS
Sbjct: 536 WYSSSSSRSASRSYSRSRSRSRSRRRSRTRTSSSSSSRS--------------------- 574
Query: 1784 PSTGGRQRSR-----HEQARDSSRHSASQEGQDTIR 1814
PS G R RSR ++R SR +S + + R
Sbjct: 575 PSPGSRSRSRSRSRSRSRSRSQSRSYSSADSYSSTR 610
Score = 65.5 bits (158), Expect = 1e-09
Identities = 135/593 (22%), Positives = 216/593 (36%), Gaps = 84/593 (14%)
Query: 2856 SRHHEASTHADISR--HSQAVQGQSEGSRRSRRQGSSVSQDSDSEGHSEDSE----RWSG 2909
+R H AS D++ S+ + + + +R+ RR+ SS S + + S+ R S
Sbjct: 89 TRGHSASHDKDLTPPPSSRGKKKKKKSTRKKRRRSSSYSPSPVKKKKKKSSKKHKRRRSF 148
Query: 2910 SASRNHHGSA-QEQLRDGSRHPR-SHQEDRAGHGHSADSSRQSGTRHTQTSSGGQAASSH 2967
S R H S+ + + RD RH + S R H H RH + S Q++ S
Sbjct: 149 SKKRRHSSSSPKSKRRDEKRHKKQSRSRPRKSHRH----------RHHRCPSRSQSSES- 197
Query: 2968 EQARSSAGERHGSHHQQSADSSRHSGIGHGQASSAVRDSGHRGYSGSQASDNEGHSEDSD 3027
+ S+ SRH G + + R R E S
Sbjct: 198 ---------------RPSSCESRHRGRSPEEGQKSRRRHSRRCSKTLCKDSPEAQSSRPP 242
Query: 3028 TQSVSAHGQAGSHQQSHQESARGRSGETSGHSGSFLYQVSTHEQSESSHGWTGPSTRGRQ 3087
+Q + G SARG T S + L+ + + S RGR
Sbjct: 243 SQPLQMLGYL---------SARGVI--TGSGSAADLFTKTASPLTTS---------RGR- 281
Query: 3088 GSRHEQAQDSSRHSASQYGQDTIRGHPGSSRGGRQGYHHEHSVDSSGHSGSHHSHTTSQG 3147
++ D+S ++Q RG S G G ++S S S +S TTS
Sbjct: 282 SQEYDSGNDTSSPPSTQTSSARSRGQEKGSPSG--GLSKSRELNSGNTSDSGNSFTTSSP 339
Query: 3148 RSDASRGQSGSRSASRTTRNEEQSGDSSRHSVSRHHEASTHADISRHSQAVQGQSEGSRR 3207
++ + + S T+R E G S + S+ + S ++G S S
Sbjct: 340 QNKGAM----LENLSPTSRGRESRGFQSPCLECAEVKKSSLVPSTARSSPMKGCSRSSSY 395
Query: 3208 SRRQGSSVSQDSDSEGHSE--DSERWSGSASRNHRGSVQEQSRHGSRHP--RSHHEDRAG 3263
+ + SS S S + S R + S R++ S S+ G R P RS R+
Sbjct: 396 ASTRSSSHSSRSPNPRASPRYTQSRSTSSEKRSYSRSPSYSSKSGKRSPPSRSSRSRRSP 455
Query: 3264 HGHSADRSRQSGTRHAE-TSSGGQAASSHEQARSSPGERHGSRHQQSADSSRHSGIPRGQ 3322
SR+ +++E S + + + RS R R S +R R +
Sbjct: 456 SYSRYSPSRERDPKYSEKDSQQRERERARRRRRSYSPMRKRRRDSPSHLEARRITSARKR 515
Query: 3323 ASSAVRDSRHWGSSGSQASDSEGHSEESDTQSVSGHGQAGPHQQSHQESARDRSGGRSGR 3382
R S SSGS +S S +S S + + + +R RS RS R
Sbjct: 516 PIPYYRPSP--SSSGSLSSTSSWYSSSSS-------------RSASRSYSRSRSRSRSRR 560
Query: 3383 SGSFLYQVSTHEQSESAHGRTRTSTGRRQGSHHEQARDSSRHSASQEGQDTIR 3435
S+ +S S R+R+ + R S ++R SR +S + + R
Sbjct: 561 RSRTRTSSSSSSRSPSPGSRSRSRSRSRSRS---RSRSQSRSYSSADSYSSTR 610
Score = 65.5 bits (158), Expect = 1e-09
Identities = 118/530 (22%), Positives = 188/530 (35%), Gaps = 59/530 (11%)
Query: 1914 QGSSVSQDSD------SQGHSEDSE------RWSGSASRNHLGSAWEQSRDGSRHPGSHH 1961
+G S S D D S+G + + R S S S + + ++S + S
Sbjct: 90 RGHSASHDKDLTPPPSSRGKKKKKKSTRKKRRRSSSYSPSPVKKKKKKSSKKHKRRRSFS 149
Query: 1962 EDRAGHGHSADSSRQSGTRHTESSSRGQAASSHEQARSSAGERHGSHHQLQSADSSRHSG 2021
+ R S S R+ RH + SR + SH R S S+ SRH G
Sbjct: 150 KKRRHSSSSPKSKRRDEKRH-KKQSRSRPRKSHRHRHHRCPSRSQSSESRPSSCESRHRG 208
Query: 2022 IGHGQASSAVRDSGHRGYSGSQASDSEGHSEDSDTQSVSAQGKAGPHQQSHKESARGQSG 2081
+ + R R S + DS ++ S++ + P Q SARG
Sbjct: 209 RSPEEGQKSRRRHSRR-CSKTLCKDSP--------EAQSSRPPSQPLQMLGYLSARGVIT 259
Query: 2082 ESSGRSGSFLYQVSTHEQSESTHGQSAPSTGGRQGSHYDQAQDSSRHSASQEGQDTIRGH 2141
S + F T S +T + YD D+S ++Q RG
Sbjct: 260 GSGSAADLF------------TKTASPLTTSRGRSQEYDSGNDTSSPPSTQTSSARSRGQ 307
Query: 2142 PGPSRGGRQGSHQEQSVDRSGHSGSHHSHTTSQGR-------SDASRGQSGSRSAS---- 2190
S G +E + + SG+ + ++ Q + S SRG+ S
Sbjct: 308 EKGSPSGGLSKSRELNSGNTSDSGNSFTTSSPQNKGAMLENLSPTSRGRESRGFQSPCLE 367
Query: 2191 ----RKTYDKEQSGDGSRHSGSHHHEASSWADSSRHSLVGQGQSSGPRTSRPRGSSVSQD 2246
+K+ + S G + + SS HS + PR ++ R +S +
Sbjct: 368 CAEVKKSSLVPSTARSSPMKGCSRSSSYASTRSSSHSSRSPNPRASPRYTQSRSTSSEKR 427
Query: 2247 SDSEGHSEDSERRSGSASRNHHGSAQEQSRDGSRHPRSHHED-----RAGHGHSAESSRQ 2301
S S S S +SG S S +S SR+ S D + E +R+
Sbjct: 428 SYSRSPSYSS--KSGKRSPPSRSSRSRRSPSYSRYSPSRERDPKYSEKDSQQRERERARR 485
Query: 2302 SGTHHAENSSGGQAASSHEQAR--SSAGERHGSHHQQSADSSRHSGIGHGQASSAVRDSG 2359
++ + + SH +AR +SA +R +++ S SS SS+ S
Sbjct: 486 RRRSYSPMRKRRRDSPSHLEARRITSARKRPIPYYRPSPSSSGSLSSTSSWYSSSSSRSA 545
Query: 2360 HRGSSGSQASDSEGHSEDSDTQSVSAHGQAGPHQQSHQES-TRGRSAGRS 2408
R S S++ + T S S+ P +S S +R RS RS
Sbjct: 546 SRSYSRSRSRSRSRRRSRTRTSSSSSSRSPSPGSRSRSRSRSRSRSRSRS 595
Score = 65.5 bits (158), Expect = 1e-09
Identities = 132/608 (21%), Positives = 219/608 (36%), Gaps = 136/608 (22%)
Query: 137 NKGRSKSPRETGGKRHESSS------EKKERKGYSPTHREEEYGKNHHNSSKKEKNKTEN 190
++G+ K + T KR SSS +KK++K R + K +SS K+K +
Sbjct: 106 SRGKKKKKKSTRKKRRRSSSYSPSPVKKKKKKSSKKHKRRRSFSKKRRHSSSSPKSKRRD 165
Query: 191 TRLGDNRKRLSERLEEKEDNEEGVYDYENTGRMTQKWIQSGHIATYYTIQDEAYDTTDSL 250
+ + R R +
Sbjct: 166 EKRHKKQSRSRPRKSHRH------------------------------------------ 183
Query: 251 LEENKIYERSRSSDGKSSSQVNRSRHENTSQVPLQESRTRKRRGSRVSQDRDSEGHSEDS 310
++ RS+SS+ + SS SRH S P + ++R+R R S+ + S
Sbjct: 184 -RHHRCPSRSQSSESRPSS--CESRHRGRS--PEEGQKSRRRHSRRCSKTLCKDSPEAQS 238
Query: 311 ERHSGSASRNHHGSAWEQSRDGSRHPRSHDEDRASHGHSADSSRQSGTRHAETSSRGQTA 370
R + + GS G +AD + T T+SRG++
Sbjct: 239 SRPPSQPLQMLGYLSARGVITGS-------------GSAADLFTK--TASPLTTSRGRS- 282
Query: 371 SSHEQARSSPGERHGSGHQQSADSSRHSATGRGQASSAVSDRGHRGSSGSQASDSEGHSE 430
+ + SG+ S+ S +++ R + S G G S S+ +S S+
Sbjct: 283 -----------QEYDSGNDTSSPPSTQTSSARSRGQEKGSPSG--GLSKSRELNSGNTSD 329
Query: 431 NSDTQSVSGHGKAGLRQQSHQESTRGRSG--------ERSGRSGSSLYQVSTHEQPDSAH 482
+ ++ + S G ++ ++RGR E + SSL + P
Sbjct: 330 SGNSFTTSSPQNKGAMLENLSPTSRGRESRGFQSPCLECAEVKKSSLVPSTARSSPMKGC 389
Query: 483 GRTGTSTGGRQGSHHEQA-------RDSSRHSASQEGQDTIRGHPGSSRGGRQGSHHEQS 535
R+ + R SH ++ R + S S E + R SS+ G++ S
Sbjct: 390 SRSSSYASTRSSSHSSRSPNPRASPRYTQSRSTSSEKRSYSRSPSYSSKSGKRSPPSRSS 449
Query: 536 VNRSGHSGSHHSHTTSQGRSDASHGQSGSRSASRQ---TRNEEQSGDGTRHSGSRHHEAS 592
RS S S+ ++ S+ R D + + S+ R+ R S R S H +
Sbjct: 450 --RSRRSPSYSRYSPSRER-DPKYSEKDSQQRERERARRRRRSYSPMRKRRRDSPSHLEA 506
Query: 593 SQADSSRHSQVGQGQSSGPRTSRNQGSSVSQDSDSQGHSEDSERWSGSASRNHHGSAQEQ 652
+ S+R + P + SS S S S +S S R SASR++ +
Sbjct: 507 RRITSARKRPI-------PYYRPSPSSSGSLSSTSSWYSSSSSR---SASRSY-----SR 551
Query: 653 SRDGSRHPRSHHEDRAGHGHSADSSRKSGTRHTQNSSSGQAASSHEQARSSAGERHGSRH 712
SR SR S R+S TR T +SSS ++ S ++RS + R SR
Sbjct: 552 SRSRSR-----------------SRRRSRTR-TSSSSSSRSPSPGSRSRSRSRSRSRSRS 593
Query: 713 QLQSADSS 720
+ QS S
Sbjct: 594 RSQSRSYS 601
Score = 64.3 bits (155), Expect = 2e-09
Identities = 120/558 (21%), Positives = 197/558 (35%), Gaps = 43/558 (7%)
Query: 3005 DSGHRGYSGSQASDNEGHSEDSDTQSVSAHGQAGSHQQSHQESARGRSGETSGHSGSFLY 3064
+S R + + GHS D G ++ ++S R + +S +S S +
Sbjct: 75 NSWERDKTCRELGATRGHSASHDKDLTPPPSSRGKKKK--KKSTRKKRRRSSSYSPSPVK 132
Query: 3065 QVSTHEQSESSHGWTGPSTRGRQGSRHEQAQDSSRHSASQYGQDTIRGHPGSSRGGRQGY 3124
+ ++S H ++ R RH + S+ + + R P S R +
Sbjct: 133 KKK--KKSSKKHKRRRSFSKKR---RHSSSSPKSKRRDEKRHKKQSRSRPRKSH--RHRH 185
Query: 3125 HHEHSVDSSGHSGSHHSHTTSQGRSDASRGQSGSRSASRTTRN------EEQSGDSSRHS 3178
H S S S + +GRS +S R + R ++ E QS
Sbjct: 186 HRCPSRSQSSESRPSSCESRHRGRSPEEGQKSRRRHSRRCSKTLCKDSPEAQSSRPPSQP 245
Query: 3179 VSRHHEASTHADISRHSQAVQGQSE-GSRRSRRQGSSVSQDSDSEGHSEDSERWSGSASR 3237
+ S I+ A ++ S + +G S DS ++ S S + S + SR
Sbjct: 246 LQMLGYLSARGVITGSGSAADLFTKTASPLTTSRGRSQEYDSGNDTSSPPSTQTSSARSR 305
Query: 3238 NHRGSVQEQSRHGSRHPRSHHEDRAGHGHSADRSRQSGT---RHAETSSGGQAASSHEQA 3294
SR S + +G+ + + G + TS G ++
Sbjct: 306 GQEKGSPSGGLSKSRELNSGNTSDSGNSFTTSSPQNKGAMLENLSPTSRGRESRGFQSPC 365
Query: 3295 RSSPGERHGSRHQQSADSSRHSGIPRGQASSAVRDSRHWGSSGS-QASDSEGHSEESDTQ 3353
+ S +A SS G R + ++ R S H S + +AS S + ++
Sbjct: 366 LECAEVKKSSLVPSTARSSPMKGCSRSSSYASTRSSSHSSRSPNPRASPRYTQSRSTSSE 425
Query: 3354 SVSGHGQAGPHQQSHQESARDRSGGRSGRSGSFLYQVSTHEQS-----ESAHGRTRTSTG 3408
S +S + S RS RS RS S+ + E+ + + R R
Sbjct: 426 KRSYSRSPSYSSKSGKRSPPSRSS-RSRRSPSYSRYSPSRERDPKYSEKDSQQRERERAR 484
Query: 3409 RRQGSH---HEQARDSSRHSASQEGQDTIRGHPGSSRRGRQGSHYEQSVDRSGHSGSHHS 3465
RR+ S+ ++ RDS H + +S R R +Y S SG S S
Sbjct: 485 RRRRSYSPMRKRRRDSPSH---------LEARRITSARKRPIPYYRPSPSSSGSLSSTSS 535
Query: 3466 HTTSQGRSDASRGQSGSRSASRQTRNDEQSGDGSRHSWSHHHEASTQADSSRHSQSGQGQ 3525
+S ASR S SRS SR R +R S S + + SR + +
Sbjct: 536 WYSSSSSRSASRSYSRSRSRSRSRRRSR-----TRTSSSSSSRSPSPGSRSRSRSRSRSR 590
Query: 3526 SAGPRTSRNQGSSVSQDS 3543
S SR+ S+ S S
Sbjct: 591 SRSRSQSRSYSSADSYSS 608
Score = 64.3 bits (155), Expect = 2e-09
Identities = 115/546 (21%), Positives = 198/546 (36%), Gaps = 58/546 (10%)
Query: 87 ESTRKENLPISGH-------KHRKHSHHDKHEDNKQEENKENRKRPSSLERRNNRKGNKG 139
+STRK+ S + K +K S K + ++ + + P S R R +
Sbjct: 114 KSTRKKRRRSSSYSPSPVKKKKKKSSKKHKRRRSFSKKRRHSSSSPKSKRRDEKRHKKQS 173
Query: 140 RSKSPRETGGKRHESSSEKKERKGYSPTHREEEYGKNHHNSSKKEKNKTENTRLGDNRKR 199
RS+ PR++ RH + + P+ E H S +E K+ K
Sbjct: 174 RSR-PRKSHRHRHHRCPSRSQSSESRPSSCE----SRHRGRSPEEGQKSRRRHSRRCSKT 228
Query: 200 LSERLEEKEDNEEGVYDYENTGRMTQKWIQSGHIATYYTIQDEAYDTTDSLLEENKIYER 259
L + E + + + G ++ + + +G + A T S R
Sbjct: 229 LCKDSPEAQSSRPPSQPLQMLGYLSARGVITGSGSAADLFTKTASPLTTS---------R 279
Query: 260 SRSSDGKSSSQVNRSRHENTSQVPLQESRTRKRRGSRVSQDRDSEGHSEDSERHSGSASR 319
RS + S + +TS P ++ + + RG + S G S+ E +SG+ S
Sbjct: 280 GRSQEYDSGN--------DTSSPPSTQTSSARSRGQ--EKGSPSGGLSKSRELNSGNTSD 329
Query: 320 NHHGSAWEQSRDGSRHPRSHDEDRASHGHSADSSRQSGTRHAETSSRGQTASSHEQARSS 379
+ G+++ S ++ + S G + + AE S+ ARSS
Sbjct: 330 S--GNSFTTSSPQNKGAMLENLSPTSRGRESRGFQSPCLECAEVKKSSLVPST---ARSS 384
Query: 380 PGERHGSGHQQSADSSRHSATGRGQASSAVSDRGHRGSSGSQASDSEGHSENSDTQSVSG 439
P G S S+R S+ +S + + R + S+++ SE + S ++S S
Sbjct: 385 P--MKGCSRSSSYASTRSSS----HSSRSPNPRASPRYTQSRSTSSE---KRSYSRSPSY 435
Query: 440 HGKAGLRQQSHQESTRGRSGERSGRSGSSLYQVSTHEQPDSAHGRTGTSTGGRQGSHHEQ 499
K+G R + S RS S + S + D + + R+ + +
Sbjct: 436 SSKSGKRSPPSRSSRSRRS--------PSYSRYSPSRERDPKYSEKDSQQRERERARRRR 487
Query: 500 ARDSSRHSASQEGQDTIRGHPGSSRGGRQGSHHEQSVNRSGHSGSHHSHTTSQGRSDASH 559
S ++ + +S R ++ S + SG S S +S AS
Sbjct: 488 RSYSPMRKRRRDSPSHLEARRITSARKRPIPYYRPSPSSSGSLSSTSSWYSSSSSRSASR 547
Query: 560 GQSGSRSASRQTRNEEQSGDGTRHSGSRHHEASSQADSSRHSQVGQGQSSGPRTSRNQGS 619
S SRS SR R TR S S + S SR + +S SR+ S
Sbjct: 548 SYSRSRSRSRSRRRSR-----TRTSSSSSSRSPSPGSRSRSRSRSRSRSRSRSQSRSYSS 602
Query: 620 SVSQDS 625
+ S S
Sbjct: 603 ADSYSS 608
Score = 62.8 bits (151), Expect = 7e-09
Identities = 108/481 (22%), Positives = 163/481 (33%), Gaps = 40/481 (8%)
Query: 2444 KQARDSSRHSTSQEGQDTIHGHPGSSSGGRQGSHYEQLVDRSGHSGSH-HSHTTSQGRSD 2502
K+ + S +H + S R+ + RS SH H H RS
Sbjct: 134 KKKKSSKKHKRRRSFSKKRRHSSSSPKSKRRDEKRHKKQSRSRPRKSHRHRHHRCPSRSQ 193
Query: 2503 ASHGHSGSRSASRQTRNDEQSGDGSRHSGSRH----------HEASSRADSSGHSQVGQG 2552
+S S + + R+ E+ G SR SR SSR S +G
Sbjct: 194 SSESRPSSCESRHRGRSPEE-GQKSRRRHSRRCSKTLCKDSPEAQSSRPPSQPLQMLGYL 252
Query: 2553 QSEGPRT----------------SRNWGSSFSQDSDSQGHSEDSERWSGSASRNHHGSAQ 2596
+ G T + + G S DS + S S + S + SR +
Sbjct: 253 SARGVITGSGSAADLFTKTASPLTTSRGRSQEYDSGNDTSSPPSTQTSSARSRGQEKGSP 312
Query: 2597 EQLRDGSRHPRSHQEDRAGHGHSADSSRQSGT---RHTQTSSGGQAASSHEQARSSAGER 2653
SR S +G+ + S + G + TS G ++ A +
Sbjct: 313 SGGLSKSRELNSGNTSDSGNSFTTSSPQNKGAMLENLSPTSRGRESRGFQSPCLECAEVK 372
Query: 2654 HGSHHQQSADSSRHSGIGHGQASSAVRDSGHRGYSGS-QASDNEGHSEDSDTQSVSAHGQ 2712
S +A SS G + ++ R S H S + +AS S + ++ S
Sbjct: 373 KSSLVPSTARSSPMKGCSRSSSYASTRSSSHSSRSPNPRASPRYTQSRSTSSEKRSYSRS 432
Query: 2713 AGSHQQSHQESARGRSGETSGHSGSFLYQVSTHEQSESSHGWTGPSTRGRQGSRHEQAQD 2772
+S + S RS S S S+ + S + + + R R+ +R +
Sbjct: 433 PSYSSKSGKRSPPSRSSR-SRRSPSYS-RYSPSRERDPKYSEKDSQQRERERARRRRRSY 490
Query: 2773 SSRHSASQDGQDTIRGHPGSSRGGRQGYHHEHSVDSSGHSGSHHSHTTSQGRSDASRGQS 2832
S +D + +S R ++ S SSG S S +S ASR S
Sbjct: 491 SPMRKRRRDSPSHLEARRITSARKRPIPYYRPSPSSSGSLSSTSSWYSSSSSRSASRSYS 550
Query: 2833 GSRSASRT-----TRNEEQSGDGSRHSGSRHHEASTHADISR-HSQAVQGQSEGSRRSRR 2886
SRS SR+ TR S S GSR S SR SQ+ S S S R
Sbjct: 551 RSRSRSRSRRRSRTRTSSSSSSRSPSPGSRSRSRSRSRSRSRSRSQSRSYSSADSYSSTR 610
Query: 2887 Q 2887
+
Sbjct: 611 R 611
Score = 45.1 bits (105), Expect = 0.001
Identities = 46/226 (20%), Positives = 85/226 (37%), Gaps = 10/226 (4%)
Query: 97 SGHKHRKHSHHDKHEDNKQEENKENRKRPSSLERRNNRKGNKGRSKSPRETGGKRHESSS 156
S + + S H N + + + R +S E+R+ + SKS + + R S
Sbjct: 393 SSYASTRSSSHSSRSPNPRASPRYTQSRSTSSEKRSYSRSPSYSSKSGKRSPPSRSSRSR 452
Query: 157 EKKERKGYSPT-HREEEYGKNHHNSSKKEKNKTENTRLGDNRKRLSERLEEKEDNEEGVY 215
YSP+ R+ +Y S+K+ + E R R+ S + + D+ +
Sbjct: 453 RSPSYSRYSPSRERDPKY-------SEKDSQQRERERARRRRRSYSPMRKRRRDSPSHLE 505
Query: 216 DYENTGRMTQ--KWIQSGHIATYYTIQDEAYDTTDSLLEENKIYERSRSSDGKSSSQVNR 273
T + + + ++ ++ ++ S ++ Y RSRS R
Sbjct: 506 ARRITSARKRPIPYYRPSPSSSGSLSSTSSWYSSSSSRSASRSYSRSRSRSRSRRRSRTR 565
Query: 274 SRHENTSQVPLQESRTRKRRGSRVSQDRDSEGHSEDSERHSGSASR 319
+ ++S+ P SR+R R SR S+ S S S R
Sbjct: 566 TSSSSSSRSPSPGSRSRSRSRSRSRSRSRSQSRSYSSADSYSSTRR 611
Score = 38.5 bits (88), Expect = 0.14
Identities = 50/230 (21%), Positives = 79/230 (34%), Gaps = 43/230 (18%)
Query: 3782 GHSGSHHSHTTSQGRSDASHGQSGSRSASRETRNEEQSGDGS------RHSGSRHHEAST 3835
GHS SH T +S G+ + ++R+ R S S + S +H +
Sbjct: 91 GHSASHDKDLTPP---PSSRGKKKKKKSTRKKRRRSSSYSPSPVKKKKKKSSKKHKRRRS 147
Query: 3836 QADSSRHSQSG-QGESAGSRRSRRQGSSVSQDSDSEAY------PEDSERRSESASRNHH 3888
+ RHS S + + +R ++Q S + S + + SE R S H
Sbjct: 148 FSKKRRHSSSSPKSKRRDEKRHKKQSRSRPRKSHRHRHHRCPSRSQSSESRPSSCESRHR 207
Query: 3889 GSSREQSRDGSRHPG---------SSHRDTASHVQSSPVQ-----------------SDS 3922
G S E+ + R S +S S P+Q +D
Sbjct: 208 GRSPEEGQKSRRRHSRRCSKTLCKDSPEAQSSRPPSQPLQMLGYLSARGVITGSGSAADL 267
Query: 3923 STAKEHGHFSSLSQDSAYHSGIQSRGSPHSSSSYHYQSEGTERQKGQSGL 3972
T +S + Y SG SP S+ + +S G E+ GL
Sbjct: 268 FTKTASPLTTSRGRSQEYDSG-NDTSSPPSTQTSSARSRGQEKGSPSGGL 316
Score = 32.7 bits (73), Expect = 7.5
Identities = 39/147 (26%), Positives = 56/147 (38%), Gaps = 22/147 (14%)
Query: 3828 SRHHEASTQADSSR--HSQSGQGESAGSRRSRRQGSSVSQDSDSEAYPEDSE---RRSES 3882
+R H AS D + S+ + + +R+ RR+ SS S + + S+ RR
Sbjct: 89 TRGHSASHDKDLTPPPSSRGKKKKKKSTRKKRRRSSSYSPSPVKKKKKKSSKKHKRRRSF 148
Query: 3883 ASRNHHGSSREQSRDGSRHPGSSHRDTASHVQSSPVQSDSSTAKEHGHFSSLSQDSAYHS 3942
+ + H SS P S RD H + S + S H S SQ S
Sbjct: 149 SKKRRHSSS---------SPKSKRRDEKRHKKQSRSRPRKSHRHRHHRCPSRSQSS---- 195
Query: 3943 GIQSRGSPHSSSSYHYQSEGTERQKGQ 3969
+SR P S S H E QK +
Sbjct: 196 --ESR--PSSCESRHRGRSPEEGQKSR 218
>gi|239754668 PREDICTED: mucin 12 [Homo sapiens]
Length = 1952
Score = 87.8 bits (216), Expect = 2e-16
Identities = 335/1562 (21%), Positives = 534/1562 (34%), Gaps = 184/1562 (11%)
Query: 2244 SQDSDSEGHSED-------SERRSGSASRNHHGSAQEQSRDGSRHPRSHHEDRAGHGHSA 2296
S D +G +E SE+ + +R S D S + HE+ + HS
Sbjct: 20 SPGDDGDGRAEGFSLGLPLSEQARAAGAREKERQEVSSSPDVSELTATKHEETVIN-HST 78
Query: 2297 ESSRQSGTHHAENSS-GGQAASSHEQARSSAGERHGSHHQQSADSSRHSGIGHGQASSAV 2355
S T N+S GG S+ + S + + + H SS
Sbjct: 79 FSGFSQITGSTVNTSIGGNTTSASTPSSSDPFTTFSDYGVSVTFITGSTATKHFLDSST- 137
Query: 2356 RDSGHR-----GSSGSQASDSEGHSEDSDTQSVSAHGQAGPHQQSHQESTR----GRSAG 2406
+SGH SG A+ + S T + P + E+T +AG
Sbjct: 138 -NSGHSEESTVSHSGPGATGTTLFPSHSATSVFVGEPKTSPITSASMETTALPGSTTTAG 196
Query: 2407 RSGRSGSFLYQVSTHEQSESAHGRTGTSTGGRQGSHHKQARDSSRH------STSQEG-- 2458
S +S +F + +++ S RT TS+G + S +R H ST+ G
Sbjct: 197 LSEKSTTFYSSPRSPDRTLSP-ART-TSSGVSEKSTTSHSRPGPTHTIAFPDSTTMPGVS 254
Query: 2459 QDTIHGH-----------PGSSSGGRQGSHYEQLVDRSGHSGSHH--SHTTSQGRSDAS- 2504
Q++ H PG+++ G G++ + +TT+ G +AS
Sbjct: 255 QESTASHSIPGSTDTTLSPGTTTPSSLGPESTTFHSSPGYTKTTRLPDNTTTSGLLEAST 314
Query: 2505 --HGHSGSR----SASRQTRNDEQSGDGSRHSGSRHHEASSRADSSGHSQVGQGQSEGPR 2558
H +GS S + T ++ + S+ + +S ++ P
Sbjct: 315 PVHSSTGSPHTTLSPASSTTHEGEPTTFQSWPSSKDTSPAPSGTTSAFVKLSTTYHSSPS 374
Query: 2559 TSRNWGSSFSQDSDSQGHSEDSERWSGSA---------SRNHHGSAQEQLRDGSRHPRSH 2609
++ + FS S + GHSE+S S +R+ E+ R P S
Sbjct: 375 STPT--THFSASSTTLGHSEESTPVHSSPVATATTPPPARSATSGHVEESTAYHRSPGST 432
Query: 2610 Q-----EDRAGHGHSADSSRQSG-TRHTQTSSGGQ-AASSHEQARSSAGERHGSHHQQSA 2662
Q E GHS +S+ G T HT++S+ AA +H SS G +H + S+
Sbjct: 433 QTMHFPESSTTSGHSEESATFHGSTTHTKSSTPSTTAALAHTSYHSSLGSTETTHFRDSS 492
Query: 2663 DSSRHSGIGHGQASSAVRDSGHRGYSGSQASDNEGHSEDSDTQSVSAHGQA--------G 2714
S S SS + +GS S G S S S S A G
Sbjct: 493 TISGRSEESKASHSSPDAMATTVLPAGSTPSVLVGDSTPSPISSGSMETTALPGSTTKPG 552
Query: 2715 SHQQSHQESARGRSGETSGHSGSFLYQVSTHEQSESSHGWTGPS-TRGRQGSRHEQ--AQ 2771
++S + RS +T+ H + + E+S +SH G + T GS +Q
Sbjct: 553 LSEKSTTFYSSPRSPDTT-HLPASMTSSGVSEESTTSHSRPGSTHTTAFPGSTTMPGLSQ 611
Query: 2772 DSSRHSASQDGQDTIRGHPGSSRGGRQG--YHHEHSVDSSGHSGSHHSHTTSQGRSDASR 2829
+S+ +S DT PGS+ G Y HS S + +TT+ G +AS
Sbjct: 612 ESTASHSSPGPTDTTLS-PGSTTASSLGPEYTTFHSRPGSTETTLLPDNTTASGLLEASM 670
Query: 2830 GQSGSRSASRTTRNEEQSGDGSRHSGSRHHEASTHADISRHSQAVQGQSEGSRRSRRQGS 2889
S + TT + S S + H S++ E S S S
Sbjct: 671 PVHSSTRSPHTTLSPAGSTTRQGESTTFHSWPSSNDTRPAPPTTTSAFVEPSTTSHGSPS 730
Query: 2890 SV-----SQDSDSEGHSEDSERWSGSASRNHHGSAQEQLRDGSRHPRSHQEDRAGHGHSA 2944
S+ S S + G E+S + S GS Q P S + +G G +
Sbjct: 731 SIPTTHISARSTTSGLVEESTTYHSSP-----GSTQTM-----HFPES--DTTSGRGEES 778
Query: 2945 DSSRQSGTRHTQTSSGGQAASSHEQA---RSSAGERHGSHHQQSADSSRHSGIGHGQASS 3001
+S S T HT +S+ ++ E+ SS G +H S+ +S G++
Sbjct: 779 TTSHSS-TTHTISSAPSTTSALVEEPTSYHSSPGSTATTHFPDSSTTS-------GRSEE 830
Query: 3002 AVRDSGHRGYSGS----QASDNEGHSEDSDTQSVSAHGQAGSHQQSHQESARGRSGETSG 3057
++ + +G+ S N +S T +S+ + + T+
Sbjct: 831 SIASHSSQDATGTIVLPARSTNSVLLGESTTSPISSGSMETTALPGSTTTPGLSERSTTF 890
Query: 3058 HSGSFLYQVSTHEQSESSHGWTGPST--RGRQGSRHEQA-QDS------SRHSASQY--- 3105
HS + S +S G + ST R GS H A DS SRHS + +
Sbjct: 891 HSSPRSPATTLSPASTTSSGVSEESTTSHSRPGSTHTTAFPDSTTTPGLSRHSTTSHSSP 950
Query: 3106 GQDTIRGHPGSSRGGRQGYHHEHSVDS-SGHSGSHHSHTTSQGRSDASRGQSGSRSASRT 3164
G P S+ G + S S + + TT+ G S+ S S + T
Sbjct: 951 GSTDTTLLPASTTTXLVGEPTTSPISSGSTETTALPGSTTTAGLSEKSTTFYSSPRSPDT 1010
Query: 3165 T---RNEEQSGDSSRHSVSRHHEASTHADISRHSQAVQGQSEGSRRSRRQGSSV------ 3215
T + SG S + S STH S + G S+ S S S
Sbjct: 1011 TLSPASTTSSGVSEESTTSHSRPGSTHTTAFPGSTTMPGVSQESTASHSSPGSTDTTLSP 1070
Query: 3216 -SQDSDSEGHSEDSERWSGSASRNHRGSVQEQSRHGSRHPRSHHEDRAGHGHSADRSRQS 3274
S + S G E + SG S + G + G + S
Sbjct: 1071 RSTTASSLG-PESTTFHSGPGSTETTLLPDNTTASGLLEASTPVHSSTGSPRTTLSPAGS 1129
Query: 3275 GTRHAETSSGGQAASSHEQARSSPGERHGSRHQQSADSSRHSGIPRGQASSAVRDSRHWG 3334
TR E+++ SS + + P + S IP + H+
Sbjct: 1130 TTRQGESTTFQSWPSSKDTMPAPPTTTSAFVELSTTSHGSPSSIP----------TTHFS 1179
Query: 3335 SSGSQASDSEGHSEESDTQSVSGHGQAGPHQQSHQESARDRSGGRSGRSGSFLYQVSTHE 3394
+S S + G SEES T S A + ++ + S Q
Sbjct: 1180 AS----STTFGRSEESTTVHSSPVAPATTPSPARSTTSGLVEESTAYHSSPGSTQTMHFP 1235
Query: 3395 QSESAHGRTRTSTGRRQGSHHEQARDSSRHSASQEGQDTIRGHPGSSRRGRQGSHYEQSV 3454
+S +A GR+ S + H + S SA E + PGS +H+ +S
Sbjct: 1236 ESSTASGRSEESRTSHSSTTHTISSPPSTTSALVEEPTSYHSSPGSIAT----THFPESS 1291
Query: 3455 DRSGHS----GSHHS-----------HTTSQGRSDASR------GQSGSRSASRQTRNDE 3493
SG S SH S H T+ GR S G + AS T
Sbjct: 1292 TTSGRSEESTASHSSPDTNGITPLPAHFTTSGRIAESTTFYISPGSMETTLASTATTPGL 1351
Query: 3494 QSGDGSRHSWSHHHEAS-TQADSSRHSQSGQGQSAGPRTSRNQGSSVSQDSDSQGHSEDS 3552
+ +S S + + + A + S SG+ S + ++ + + G S++S
Sbjct: 1352 SAKSTILYSSSRSPDQTLSPASMTSSSISGEPTSLYSQAESTHTTAFPASTTTSGLSQES 1411
Query: 3553 ERW---SGSASRNHRGSAQEQSRDGSRHPTSHHEDRAGHGHSAESSRQSGTHHAENSSGG 3609
+ GS + S T H + + + +S E+++
Sbjct: 1412 TTFHSKPGSTETTLSPGSITTSSFAQEFTTPHSQPGSALSTVSPASTTVPGLSEESTTFY 1471
Query: 3610 QAASSHEQARSSAGERHGSHHQQSADSSRHSGIGHG--QASSAVRDSGHRGSSGSQASDS 3667
+ S E S H QQS G H A+ D G ++ +SD+
Sbjct: 1472 SSPGSTETTAFSHSNTMSIHSQQSTPFPDSPGFTHTVLPATLTTTDIGQESTAFHSSSDA 1531
Query: 3668 EG 3669
G
Sbjct: 1532 TG 1533
Score = 83.2 bits (204), Expect = 5e-15
Identities = 302/1418 (21%), Positives = 470/1418 (33%), Gaps = 182/1418 (12%)
Query: 1969 HSADSSRQSGTRHTESSS---RGQAAS------SHEQARSSAGERHGSHHQLQSADSSRH 2019
H DSS SG H+E S+ G A+ SH GE S S +++
Sbjct: 131 HFLDSSTNSG--HSEESTVSHSGPGATGTTLFPSHSATSVFVGEPKTSPITSASMETTAL 188
Query: 2020 SGIGHGQASSAVRDSGHRGYSGSQASD---------SEGHSEDSDTQSVSAQGKAGPHQQ 2070
G ++ + + YS ++ D S G SE S T + + GP
Sbjct: 189 PG---STTTAGLSEKSTTFYSSPRSPDRTLSPARTTSSGVSEKSTT----SHSRPGPTHT 241
Query: 2071 SHKESARGQSGESSGRSGSFLYQVSTHEQSESTHGQSAPSTGGRQGSHYDQAQDSSRHSA 2130
+ G S + S ST + + G + PS+ G + + + + ++ +
Sbjct: 242 IAFPDSTTMPGVSQESTASHSIPGST--DTTLSPGTTTPSSLGPESTTFHSSPGYTKTTR 299
Query: 2131 SQEGQDT--IRGHPGPSRGGRQGSHQEQS-VDRSGHSGSHHSHTTSQGRSDASRGQSGSR 2187
+ T + P H S + H G + + D S SG+
Sbjct: 300 LPDNTTTSGLLEASTPVHSSTGSPHTTLSPASSTTHEGEPTTFQSWPSSKDTSPAPSGTT 359
Query: 2188 SASRKTYDKEQSGDGSRHSGSHHHEASSWADSSRHSLVGQGQSSGPRTSRPRGSSVSQD- 2246
SA K S S + + H ASS + +G + S P S P ++ +
Sbjct: 360 SAFVKLSTTYHSSPSS--TPTTHFSASS-------TTLGHSEESTPVHSSPVATATTPPP 410
Query: 2247 --SDSEGHSEDSERRSGSASRNHHGSAQEQSRDGSRHPRSHHEDRAGHGHSAESSRQSG- 2303
S + GH E+S +H S GS E GHS ES+ G
Sbjct: 411 ARSATSGHVEESTA--------YHRSP------GSTQTMHFPESSTTSGHSEESATFHGS 456
Query: 2304 -THHAENSSGGQAASSHEQARSSAGERHGSHHQQSADSSRHSGIGHGQASSAVRDSGHRG 2362
TH ++ AA +H SS G +H + S+ S S SS +
Sbjct: 457 TTHTKSSTPSTTAALAHTSYHSSLGSTETTHFRDSSTISGRSEESKASHSSPDAMATTVL 516
Query: 2363 SSGSQASDSEGHSEDSDTQSVSAHGQAGPHQQSHQESTRGRSAGRSGRSGSFLYQVSTHE 2422
+GS S G S S S S A P + G S +S +F S+
Sbjct: 517 PAGSTPSVLVGDSTPSPISSGSMETTALPGSTT--------KPGLSEKSTTF---YSSPR 565
Query: 2423 QSESAH-GRTGTSTGGRQGSHHKQARDSSRHSTSQEGQDTIHGHPGSSSGGRQGSHYEQL 2481
++ H + TS+G + S +R S H+T+ G T+ G S+
Sbjct: 566 SPDTTHLPASMTSSGVSEESTTSHSRPGSTHTTAFPGSTTMPGLSQEST----------- 614
Query: 2482 VDRSGHSGSHHSHTT-SQGRSDAS---------HGHSGSRSASRQTRNDEQSGDGSRHSG 2531
+ HS + TT S G + AS H GS + N SG
Sbjct: 615 ---ASHSSPGPTDTTLSPGSTTASSLGPEYTTFHSRPGSTETTLLPDNTTASG---LLEA 668
Query: 2532 SRHHEASSRADSSGHSQVGQGQSEGPRTS-RNWGSSFSQDSDSQGHSEDSERWSGSASRN 2590
S +S+R+ + S G +G T+ +W SS +D++ + S
Sbjct: 669 SMPVHSSTRSPHTTLSPAGSTTRQGESTTFHSWPSS----NDTRPAPPTTTSAFVEPSTT 724
Query: 2591 HHGSAQEQLRDGSRHPRSHQEDRAGHGHSADSSRQSGTRHTQTSSGGQAASSHEQARSSA 2650
HGS S P +H R+ ++ +S T H+ S S
Sbjct: 725 SHGSP-------SSIPTTHISARS---TTSGLVEESTTYHSSPGSTQTMHFPESDTTSGR 774
Query: 2651 GERHGSHHQQSADSSRHSGIGHGQASSAVRDSGHRGYSGSQASDNEGHSEDSDTQSVSAH 2710
GE + H SS I ++++ Y S S H DS T S +
Sbjct: 775 GEESTTSH-----SSTTHTISSAPSTTSALVEEPTSYHSSPGSTATTHFPDSSTTSGRSE 829
Query: 2711 GQAGSHQQSHQESARGRSGETSGHSGSFLYQVSTHEQSESSHGWTGPSTRGRQGSRHEQA 2770
SH + A G + + S L ST SS + G +
Sbjct: 830 ESIASHS---SQDATGTIVLPARSTNSVLLGEST-TSPISSGSMETTALPGSTTTPGLSE 885
Query: 2771 QDSSRHSASQDGQDTIRGHPGSSRGGRQGYHHEHSVDSSGHSGSHHSHTTSQG---RSDA 2827
+ ++ HS+ + T+ +S G + HS S H+ + TT+ G S
Sbjct: 886 RSTTFHSSPRSPATTLSPASTTSSGVSEESTTSHSRPGSTHTTAFPDSTTTPGLSRHSTT 945
Query: 2828 SRGQSGSRS-----ASRTTRNEEQSGDGSRHSGSRHHEA----STHADISRHSQAVQGQS 2878
S GS AS TT + SGS A +T A +S S
Sbjct: 946 SHSSPGSTDTTLLPASTTTXLVGEPTTSPISSGSTETTALPGSTTTAGLSEKSTTFYSSP 1005
Query: 2879 EGSRRSRRQGSSVSQDSDSEGHSEDSERWSGSASRNHHGSAQEQLRDGS-RHPRSHQEDR 2937
+ S+ S G SE+S + S + GS GS P QE
Sbjct: 1006 RSPDTTLSPASTT-----SSGVSEES-----TTSHSRPGSTHTTAFPGSTTMPGVSQEST 1055
Query: 2938 AGHGHSADSSRQSGTRHTQTSSGGQAASSHEQARSSA-----GERHGSHHQQSADSSRHS 2992
A H + R T SS G +++ S + + A + HS
Sbjct: 1056 ASHSSPGSTDTTLSPRSTTASSLGPESTTFHSGPGSTETTLLPDNTTASGLLEASTPVHS 1115
Query: 2993 GIGH-----GQASSAVRDSGHRGYSGSQASDNEGHSEDSDTQ-----SVSAHGQAGSHQQ 3042
G A S R + +S + + + T S ++HG S
Sbjct: 1116 STGSPRTTLSPAGSTTRQGESTTFQSWPSSKDTMPAPPTTTSAFVELSTTSHGSPSSIPT 1175
Query: 3043 SH---QESARGRSGETSGHSGSFLYQVSTH-----------EQSESSHGWTGPSTRGRQG 3088
+H + GRS E++ S + +T E+S + H G ST+
Sbjct: 1176 THFSASSTTFGRSEESTTVHSSPVAPATTPSPARSTTSGLVEESTAYHSSPG-STQTMHF 1234
Query: 3089 SRHEQAQDSSRHSASQYGQ--DTIRGHPGSSRGGRQGYHHEHSVDSSGHSGSHHSHTTSQ 3146
A S S + + TI P ++ + HS S + +T+
Sbjct: 1235 PESSTASGRSEESRTSHSSTTHTISSPPSTTSALVEEPTSYHSSPGSIATTHFPESSTTS 1294
Query: 3147 GRSDASRGQSGSRSASRTTRNEEQSGDSSRHSVSRHHEASTHADISRHSQAVQGQSEGSR 3206
GRS+ S S + T S R + S S + + + ++
Sbjct: 1295 GRSEESTASHSSPDTNGITPLPAHFTTSGRIAESTTFYISPGSMETTLASTATTPGLSAK 1354
Query: 3207 RSRRQGSSVSQDSDSEGHSEDSERWSGSASRNHRGSVQEQSRHGSRHPRSHHEDRAGHGH 3266
+ SS S D S S SG + + Q +S H + P S
Sbjct: 1355 STILYSSSRSPDQTLSPASMTSSSISGEPTSLYS---QAESTHTTAFPASTTTSGLSQES 1411
Query: 3267 SADRSRQSGTRHAETSSGGQAASSHEQARSSPGERHGS 3304
+ S+ G+ S G SS Q ++P + GS
Sbjct: 1412 TTFHSK-PGSTETTLSPGSITTSSFAQEFTTPHSQPGS 1448
Score = 76.3 bits (186), Expect = 6e-13
Identities = 323/1588 (20%), Positives = 504/1588 (31%), Gaps = 238/1588 (14%)
Query: 333 SRHPRSHDEDRASHGHSADSSRQSGTRHAETSSRGQTASSHEQARSSPGERHGSGHQQSA 392
+R + +++R S D S + T+H ET T S Q S G+ SA
Sbjct: 42 ARAAGAREKERQEVSSSPDVSELTATKHEETVINHSTFSGFSQITGSTVNTSIGGNTTSA 101
Query: 393 DSSRHSATGRGQASSAVSDRGHRGSSGSQ----ASDSEGHSENSDTQSVSGHGKAGLRQQ 448
+ S + VS GS+ ++ +S + GHSE S T S SG G G
Sbjct: 102 STPSSSDPFTTFSDYGVSVTFITGSTATKHFLDSSTNSGHSEES-TVSHSGPGATGTTLF 160
Query: 449 SHQESTRGRSGE---------------------RSGRSGSSLYQVSTHEQPDS--AHGRT 485
+T GE +G S S S+ PD + RT
Sbjct: 161 PSHSATSVFVGEPKTSPITSASMETTALPGSTTTAGLSEKSTTFYSSPRSPDRTLSPART 220
Query: 486 GTSTGGRQGSHHEQARDSSRHSASQEGQDTIRG-------------------HPG----S 522
TS+G + S +R H+ + T+ G PG S
Sbjct: 221 -TSSGVSEKSTTSHSRPGPTHTIAFPDSTTMPGVSQESTASHSIPGSTDTTLSPGTTTPS 279
Query: 523 SRGGRQGSHHEQ-----------SVNRSG--------HSGSHHSHTTSQGRSDASH-GQS 562
S G + H + SG HS + HTT S +H G+
Sbjct: 280 SLGPESTTFHSSPGYTKTTRLPDNTTTSGLLEASTPVHSSTGSPHTTLSPASSTTHEGEP 339
Query: 563 GSRSASRQTRNEEQSGDGTRHS----GSRHHEASSQADSSRHSQ----VGQGQSSGPRTS 614
+ + +++ + GT + + +H + S ++ S +G + S P S
Sbjct: 340 TTFQSWPSSKDTSPAPSGTTSAFVKLSTTYHSSPSSTPTTHFSASSTTLGHSEESTPVHS 399
Query: 615 ---------------------------RNQGSSVS----QDSDSQGHSEDSERWSGSASR 643
R+ GS+ + + S + GHSE+S + GS +
Sbjct: 400 SPVATATTPPPARSATSGHVEESTAYHRSPGSTQTMHFPESSTTSGHSEESATFHGSTT- 458
Query: 644 NHHGSAQEQSRDGSRHPRSHHEDRAG--HGHSADSSRKSGTRHTQNSSSGQAASSHEQAR 701
H + S + S+H H DSS SG S +A+ S A
Sbjct: 459 --HTKSSTPSTTAALAHTSYHSSLGSTETTHFRDSSTISG-----RSEESKASHSSPDAM 511
Query: 702 SSAGERHGSRHQLQSADSSRHSGTGHGQASSAVRDSGHRGSSGSQATDSEGHSEDSDTQS 761
++ GS + DS+ + ++A+ S T G SE S T
Sbjct: 512 ATTVLPAGSTPSVLVGDSTPSPISSGSMETTALPGS----------TTKPGLSEKSTTFY 561
Query: 762 VSGHGQAGHHQQSHQESARDRSGERSRRSGSFLYQVSTHKQSESSHGWTGPSTGVRQGSH 821
S H + S SG ++H + S+H P + G
Sbjct: 562 SSPRSPDTTHLPASMTS-----------SGVSEESTTSHSRPGSTHTTAFPGSTTMPGLS 610
Query: 822 HEQARDNSRHSASQDGQDTIRGHPGSSRRGRQGSHHEQSVDRSGHSGSH--HSHTTSQGR 879
E S S S G PGS+ G + R G + + +TT+ G
Sbjct: 611 QE-----STASHSSPGPTDTTLSPGSTTASSLGPEYTTFHSRPGSTETTLLPDNTTASGL 665
Query: 880 SDASRGQSGSRSASRTTRNEEQSRDGSRHSGSRHHEASSHADISRHSQAGQGQSEGSRTS 939
+AS S + TT + S S + H SS+ E S TS
Sbjct: 666 LEASMPVHSSTRSPHTTLSPAGSTTRQGESTTFHSWPSSNDTRPAPPTTTSAFVEPSTTS 725
Query: 940 RRQGSS-----VSQDSDSEGHSEDSERW---SGSASRNHRGSAQEQSRHGSRHPRSHHED 991
SS +S S + G E+S + GS H + S G SH
Sbjct: 726 HGSPSSIPTTHISARSTTSGLVEESTTYHSSPGSTQTMHFPESDTTSGRGEESTTSH--S 783
Query: 992 RAGHGHSADSSRQSG---TPHAETSSGGQAASSH--EQARSSPGERHGSRHQQSADSSRH 1046
H S+ S S P + SS G A++H + + +S S D++
Sbjct: 784 STTHTISSAPSTTSALVEEPTSYHSSPGSTATTHFPDSSTTSGRSEESIASHSSQDATGT 843
Query: 1047 SGIPRRQASSAVRDSGHWG--SSGSQ-------ASDSEGHSEESDT-----QSVSGHGQD 1092
+P R +S + SSGS ++ + G SE S T +S +
Sbjct: 844 IVLPARSTNSVLLGESTTSPISSGSMETTALPGSTTTPGLSERSTTFHSSPRSPATTLSP 903
Query: 1093 GPHQQSHQESARDWSGGRSGRSGSFIYQVSTHEQSESAHGRT------RTSTGRRQGSHH 1146
S S R G + + + ST S H T T T S
Sbjct: 904 ASTTSSGVSEESTTSHSRPGSTHTTAFPDSTTTPGLSRHSTTSHSSPGSTDTTLLPASTT 963
Query: 1147 EQARDSSRHSASQEGQDTIRAHPGS--RRGGRQGSHHEQSVDRSGHSGSHHSHTTSQG-- 1202
S G A PGS G + S S RS + + TTS G
Sbjct: 964 TXLVGEPTTSPISSGSTETTALPGSTTTAGLSEKSTTFYSSPRSPDTTLSPASTTSSGVS 1023
Query: 1203 -RSDASHGQSGSRSASRQTRKDKQSGDGSRHSGSRHHEAASWADSSRHSQVGQEQSSG-S 1260
S SH + GS + G + S H + D++ + S G
Sbjct: 1024 EESTTSHSRPGSTHTTAFPGSTTMPGVSQESTAS--HSSPGSTDTTLSPRSTTASSLGPE 1081
Query: 1261 RTSRHQGSSVSQDSDSERHSDDSERLSGSASRNHHGSSREQSRDGSRHPGFHQEDRASHG 1320
T+ H G ++ + ++ S L S + S + + E
Sbjct: 1082 STTFHSGPGSTETTLLPDNTTASGLLEASTPVHSSTGSPRTTLSPAGSTTRQGESTTFQS 1141
Query: 1321 HSADSSRQSGTHHTESSSHGQAVSSHEQARSSPGERHGSRHQQSADSSRHSGIGHRQASS 1380
+ T S+ + +SH S P + S + + +
Sbjct: 1142 WPSSKDTMPAPPTTTSAFVELSTTSHGSPSSIPTTHFSASSTTFGRSEESTTVHSSPVAP 1201
Query: 1381 AVRDSGHRGSSGSQVTNSEG-HSEDSDTQ------SVSAHGQAGPHQQSHKESARGQSGE 1433
A S R ++ V S HS TQ S +A G++ + SH + S
Sbjct: 1202 ATTPSPARSTTSGLVEESTAYHSSPGSTQTMHFPESSTASGRSEESRTSHSSTTHTISSP 1261
Query: 1434 SSGRSRSFLYQVSSHEQSES---THGQTAPSTGGRQGSRHEQARNSSRHSASQDGQDTIR 1490
S S S H S TH + +T GR + +S S +G +
Sbjct: 1262 PSTTSALVEEPTSYHSSPGSIATTHFPESSTTSGR-----SEESTASHSSPDTNGITPLP 1316
Query: 1491 GH----------------PGSSRGGRQGSYHEQSVDRSGHSGYHHSHTTPQGRSDASHGQ 1534
H PGS + + Y S + Q S AS
Sbjct: 1317 AHFTTSGRIAESTTFYISPGSMETTLASTATTPGLSAKSTILYSSSRSPDQTLSPASMTS 1376
Query: 1535 SGPRSASRQTRNEEQSGDGSRHSGSRHHEPSTRAGSSRHSQVGQGE---SAGSKTSRRQG 1591
S ++ +S + S ++ ++ HS+ G E S GS T+
Sbjct: 1377 SSISGEPTSLYSQAESTHTTAFPASTTTSGLSQESTTFHSKPGSTETTLSPGSITT---- 1432
Query: 1592 SSVSQDRDSEGHSEDSERRSESASRNHYGSAREQSRHGSRNPRSHQEDRASHGHSAESSR 1651
SS +Q+ + S + S + E+S +P S + SH ++
Sbjct: 1433 SSFAQEFTTPHSQPGSALSTVSPASTTVPGLSEESTTFYSSPGSTETTAFSHSNTMSIHS 1492
Query: 1652 QSGTRHAETSSGGQAASSQEQARSSPGERHGSRHQQSADSSTDSGTGRRQDSSVVGDSGN 1711
Q T ++ + G+ + H S + T R S +VG+
Sbjct: 1493 QQSTPFPDSPGFTHTVLPATLTTTDIGQESTAFHSSSDATGTTPLPARSTASDLVGEPTT 1552
Query: 1712 RGSSGS--------QASDSEGHSEESDT 1731
S S +S + G +EES T
Sbjct: 1553 FYISPSPTYTTLFPASSSTSGLTEESTT 1580
Score = 72.4 bits (176), Expect = 9e-12
Identities = 303/1411 (21%), Positives = 481/1411 (34%), Gaps = 142/1411 (10%)
Query: 2618 HSADSSRQSGTRHTQT-SSGGQAAS------SHEQARSSAGERHGSHHQQSADSSRHSGI 2670
H DSS SG T S G A+ SH GE S ++ S + +
Sbjct: 131 HFLDSSTNSGHSEESTVSHSGPGATGTTLFPSHSATSVFVGEPKTS--PITSASMETTAL 188
Query: 2671 GHGQASSAVRDSGHRGYSGSQASDN-----EGHSEDSDTQSVSAHGQAG-SHQQSHQESA 2724
++ + + YS ++ D S +S ++H + G +H + +S
Sbjct: 189 PGSTTTAGLSEKSTTFYSSPRSPDRTLSPARTTSSGVSEKSTTSHSRPGPTHTIAFPDST 248
Query: 2725 R--GRSGE-TSGHSGSFLYQVSTHEQSESSHGWTGPSTRGRQGSRHEQAQDSSRHSASQD 2781
G S E T+ HS + + S G T PS+ G + + + ++ + D
Sbjct: 249 TMPGVSQESTASHS------IPGSTDTTLSPGTTTPSSLGPESTTFHSSPGYTKTTRLPD 302
Query: 2782 GQDTIRGHPGSSRGGRQGYHHEHSVDSSGHSGSHHSHTTS----QGRSDASRGQSGSRSA 2837
T G +S H+ S S +H T+ D S SG+ SA
Sbjct: 303 NTTT-SGLLEASTPVHSSTGSPHTTLSPASSTTHEGEPTTFQSWPSSKDTSPAPSGTTSA 361
Query: 2838 S---RTTRNEEQSGDGSRHSGSRHHEASTHADISRHSQAVQGQSEGSRRSRRQGSSVSQD 2894
TT + S + H + +ST S S V + + S +
Sbjct: 362 FVKLSTTYHSSPSSTPTTHFSA----SSTTLGHSEESTPVHSSPVATATTPPPARSATS- 416
Query: 2895 SDSEGHSEDSERWSGSASRNHHGSAQEQLRDGSRHPRSHQEDRAGHGHSADSSRQSG-TR 2953
GH E+S + S GS E GHS +S+ G T
Sbjct: 417 ----GHVEESTAYHRSP--------------GSTQTMHFPESSTTSGHSEESATFHGSTT 458
Query: 2954 HTQTSSGGQ-AASSHEQARSSAGERHGSHHQQSADSSRHSGIGHGQASSAVRDSGHRGYS 3012
HT++S+ AA +H SS G +H + S+ S S SS + +
Sbjct: 459 HTKSSTPSTTAALAHTSYHSSLGSTETTHFRDSSTISGRSEESKASHSSPDAMATTVLPA 518
Query: 3013 GSQASDNEGHSEDSDTQSVSAHGQA--------GSHQQSHQESARGRSGETSGHSGSFLY 3064
GS S G S S S S A G ++S + RS +T+ H + +
Sbjct: 519 GSTPSVLVGDSTPSPISSGSMETTALPGSTTKPGLSEKSTTFYSSPRSPDTT-HLPASMT 577
Query: 3065 QVSTHEQSESSHGWTGPS-TRGRQGSRHEQ--AQDSSRHSASQYGQDTIRGHPGSSRGGR 3121
E+S +SH G + T GS +Q+S+ +S DT PGS+
Sbjct: 578 SSGVSEESTTSHSRPGSTHTTAFPGSTTMPGLSQESTASHSSPGPTDTTLS-PGSTTASS 636
Query: 3122 QG--YHHEHSVDSSGHSGSHHSHTTSQGRSDASRGQSGSRSASRTTRNEEQSGDSSRHSV 3179
G Y HS S + +TT+ G +AS S + TT + S S
Sbjct: 637 LGPEYTTFHSRPGSTETTLLPDNTTASGLLEASMPVHSSTRSPHTTLSPAGSTTRQGEST 696
Query: 3180 SRHHEASTHADISRHSQAVQGQSEGSRRSRRQGSSV-----SQDSDSEGHSEDSERWSGS 3234
+ H S++ E S S SS+ S S + G E+S + S
Sbjct: 697 TFHSWPSSNDTRPAPPTTTSAFVEPSTTSHGSPSSIPTTHISARSTTSGLVEESTTYHSS 756
Query: 3235 ASRNHRGSVQEQSRHGSRHPRSHHEDRAGHGHSADRSRQSGTRHAETSSGGQAASSHEQA 3294
GS Q P S + +G G + S S T ++ +A E
Sbjct: 757 P-----GSTQTM-----HFPES--DTTSGRGEESTTSHSSTTHTISSAPSTTSALVEEPT 804
Query: 3295 --RSSPGERHGSRHQQSADSSRHSGIPRGQASSAVRDSRHWGSSGSQASDSE--GHSEES 3350
SSPG + S+ +S S AS + +D+ +++++S G S S
Sbjct: 805 SYHSSPGSTATTHFPDSSTTSGRS--EESIASHSSQDATGTIVLPARSTNSVLLGESTTS 862
Query: 3351 DTQSVSGHGQAGPHQQSHQESARDRSGGRSGRSGSFLYQVSTHEQSESAHGRTRTSTGRR 3410
S S A P + + G S RS +F S + + + TS+G
Sbjct: 863 PISSGSMETTALPGSTT--------TPGLSERSTTF--HSSPRSPATTLSPASTTSSGVS 912
Query: 3411 QGSHHEQARDSSRHSASQEGQDTIRGHPGSSRRGRQGSHYEQSVDRSGHSGSHHSHTTSQ 3470
+ S +R S H+ + T PG SR S D + S + T
Sbjct: 913 EESTTSHSRPGSTHTTAFPDSTTT---PGLSRHSTTSHSSPGSTDTTLLPAS--TTTXLV 967
Query: 3471 GRSDASRGQSGSRSASRQTRNDEQSGDGSRHSWSHHHEASTQADSSRHSQSGQGQSAGPR 3530
G S SGS + + +G + + + S S S + G S
Sbjct: 968 GEPTTSPISSGSTETTALPGSTTTAGLSEKSTTFYSSPRSPDTTLSPASTTSSGVSEEST 1027
Query: 3531 TSRNQGSS--------------VSQDSDSQGHSEDSERW-----SGSASRNHRGSAQEQS 3571
TS ++ S VSQ+S + S S S +AS S S
Sbjct: 1028 TSHSRPGSTHTTAFPGSTTMPGVSQESTASHSSPGSTDTTLSPRSTTASSLGPESTTFHS 1087
Query: 3572 RDGSRHPTSHHEDRAGHGHSAESSRQSGTHHAENSSGGQAASSHEQARSSAGERH-GSHH 3630
GS T ++ G S+ + + ++ A S+ Q S+ + S
Sbjct: 1088 GPGSTETTLLPDNTTASGLLEASTPVHSSTGSPRTTLSPAGSTTRQGESTTFQSWPSSKD 1147
Query: 3631 QQSADSSRHSGIGHGQASSAVRDSGHRGSSGSQASDSEGHSEDSDTQSVSAHGQAGPHQQ 3690
A + S +S S + S +S + G SE+S T S A
Sbjct: 1148 TMPAPPTTTSAFVELSTTSHGSPSSIPTTHFSASSTTFGRSEESTTVHSSPVAPATTPSP 1207
Query: 3691 SHQESTRGRSAGRSGRSGSFLYQVSTHEQSESAHGRAGPSTGGRQGSRHEQARDSSRHSA 3750
+ ++ + S Q +S +A GR+ S + H + S SA
Sbjct: 1208 ARSTTSGLVEESTAYHSSPGSTQTMHFPESSTASGRSEESRTSHSSTTHTISSPPSTTSA 1267
Query: 3751 SQEGQDTIRGHPGSRRGGRQGSYHEQSVDRSGHS----GSHHSHTTSQGRSDASHGQSGS 3806
E + PGS ++ +S SG S SH S T+ +H +
Sbjct: 1268 LVEEPTSYHSSPGS----IATTHFPESSTTSGRSEESTASHSSPDTNGITPLPAHFTTSG 1323
Query: 3807 RSASRETRNEEQSGDGSRHSGSRHHEASTQADSSRHSQSGQGESAGSRRSRRQGSSVSQD 3866
R A T + + + + + +S S + S S S +
Sbjct: 1324 RIAESTTFYISPGSMETTLASTATTPGLSAKSTILYSSSRSPDQTLSPASMTSSSISGEP 1383
Query: 3867 SDSEAYPEDSERRSESASRNHHGSSREQSRDGSRHPGSSHR--DTASHVQSSPVQSDSST 3924
+ + E + + AS G S+E + S+ PGS+ S SS Q ++
Sbjct: 1384 TSLYSQAESTHTTAFPASTTTSGLSQESTTFHSK-PGSTETTLSPGSITTSSFAQEFTTP 1442
Query: 3925 AKEHGH-FSSLSQDSAYHSGIQSRGSPHSSS 3954
+ G S++S S G+ + SS
Sbjct: 1443 HSQPGSALSTVSPASTTVPGLSEESTTFYSS 1473
Score = 72.0 bits (175), Expect = 1e-11
Identities = 291/1434 (20%), Positives = 487/1434 (33%), Gaps = 189/1434 (13%)
Query: 973 SAQEQSRHGSRH----------PRSHHEDRAGHG--HSADSSRQSGTPHAETSSGGQAAS 1020
S SR G H P E A H S D++ GT +S G ++ +
Sbjct: 229 STTSHSRPGPTHTIAFPDSTTMPGVSQESTASHSIPGSTDTTLSPGTT-TPSSLGPESTT 287
Query: 1021 SHEQARSSPGERHGSRHQQSADSSRHSGIPRRQASSAVRDSGHWGSSGSQASDSEGHSEE 1080
H SSPG +R D++ SG+ +AS+ V S +GS H+
Sbjct: 288 FH----SSPGYTKTTR---LPDNTTTSGL--LEASTPVHSS-----TGSP------HTTL 327
Query: 1081 SDTQSVSGHGQDGPHQQSHQESARDWSGGRSGRSGSFIYQVSTHEQSESAHGRTRTSTGR 1140
S S + G+ Q S++D S SG + +F+ +T+ S S+ T S
Sbjct: 328 SPASSTTHEGEPTTFQS--WPSSKDTSPAPSGTTSAFVKLSTTYHSSPSSTPTTHFSASS 385
Query: 1141 RQGSHHEQARDSSRHSASQEGQDTIRAHPGSRRGGRQGSHHEQSVDRSGHSGSHHSHTTS 1200
H E++ + HS+ T P +R SGH ++ S
Sbjct: 386 TTLGHSEES--TPVHSSPVA---TATTPPPARSA------------TSGHVEESTAYHRS 428
Query: 1201 QGRSDASHGQSGSRSASRQTRKDKQSGDGSRHSGSRHHEAASWADSSRHSQVGQEQSSGS 1260
G + H S ++ G + S A+ A +S HS +G +++
Sbjct: 429 PGSTQTMHFPESSTTSGHSEESATFHGSTTHTKSSTPSTTAALAHTSYHSSLGSTETTHF 488
Query: 1261 RTSRHQGSSVSQDSDSERHSDDSERLS--------------GSASRNHHGSSREQSRDGS 1306
R S S S++S + S D+ + + S GS + GS
Sbjct: 489 RDSSTI-SGRSEESKASHSSPDAMATTVLPAGSTPSVLVGDSTPSPISSGSMETTALPGS 547
Query: 1307 R-HPGFHQEDRASHGHSADSSRQSGTHHTESSSHGQAVSSHEQ-ARSSPGERHGSRHQQS 1364
PG ++ + S R T H +S VS + S PG H + S
Sbjct: 548 TTKPGLSEKSTTFYS----SPRSPDTTHLPASMTSSGVSEESTTSHSRPGSTHTTAFPGS 603
Query: 1365 ADSSRHSGIGHRQASSAVRDSGHRGSSGSQVTNSEGHSEDSDT--QSVSAHGQAGPHQQS 1422
G Q S+A H + T S G + S + + H + G S
Sbjct: 604 TTMP-----GLSQESTA----SHSSPGPTDTTLSPGSTTASSLGPEYTTFHSRPG----S 650
Query: 1423 HKESARGQSGESSGRSRSFLYQVSSHEQSESTHGQTAPSTGGRQGSRHEQARNSSRHS-- 1480
+ + + +SG + + H + S H +P+ GS Q +++ HS
Sbjct: 651 TETTLLPDNTTASGLLEA---SMPVHSSTRSPHTTLSPA-----GSTTRQGESTTFHSWP 702
Query: 1481 ASQDGQD------TIRGHPGSSRGGRQGSYHEQSVD-RSGHSGYHHSHTTPQGRSDASHG 1533
+S D + + P ++ G S + RS SG TT ++
Sbjct: 703 SSNDTRPAPPTTTSAFVEPSTTSHGSPSSIPTTHISARSTTSGLVEESTTYHSSPGSTQT 762
Query: 1534 QSGPRSASRQTRNEEQSGDGSRHSGSRHHEPSTRAGSSRHSQVGQGESAGSKTSRRQGSS 1593
P S + R EE + S + + PST + + T+ SS
Sbjct: 763 MHFPESDTTSGRGEESTTSHSSTTHTISSAPSTTSALVEEPTSYHSSPGSTATTHFPDSS 822
Query: 1594 VSQDRDSE-----------------GHSEDSERRSESASRNHYGSAREQSRHGSRNPRSH 1636
+ R E S +S ES + + E +
Sbjct: 823 TTSGRSEESIASHSSQDATGTIVLPARSTNSVLLGESTTSPISSGSMETTALPGSTTTPG 882
Query: 1637 QEDRASHGHSAESSRQSGTRHAETSSGGQAASSQEQARSSPGERHGSRHQQSADSSTDSG 1696
+R++ HS+ S + A T+S G + S + S PG H + DS+T G
Sbjct: 883 LSERSTTFHSSPRSPATTLSPASTTSSGVSEES-TTSHSRPGSTHTTAF---PDSTTTPG 938
Query: 1697 TGRRQDSSVVGDSGNRGSSGSQASDSEGHSEESDTQSVSAHGQAGPHQQSHQESTRGQSG 1756
R +S G+ ++ AS + E T +S+ G +T G S
Sbjct: 939 LSRHSTTS-HSSPGSTDTTLLPASTTTXLVGEPTTSPISS-GSTETTALPGSTTTAGLSE 996
Query: 1757 ERSGRSGSFLYQVSTHEQSESAHGRTGPSTGGRQRSRHEQARDSSRHSASQEGQDTIRG- 1815
+ S + S + + S+G + S +R S H+ + G T+ G
Sbjct: 997 K------STTFYSSPRSPDTTLSPASTTSSGVSEESTTSHSRPGSTHTTAFPGSTTMPGV 1050
Query: 1816 -----HPGSSRGGRQGSHYEQSVDSSG---HSGSHHSHTTSQERSDVSRGQSGSRSVSRQ 1867
SS G + +S +S S + HS S E + + + S +
Sbjct: 1051 SQESTASHSSPGSTDTTLSPRSTTASSLGPESTTFHSGPGSTETTLLPDNTTASGLLEAS 1110
Query: 1868 TRNEKQSGDGSRHSGSRHHEASSRADSSRHSQVGQGQSSGPRTSRNQGSSVSQDSDSQGH 1927
T +G R + S + + +S+ + + P + V + S G
Sbjct: 1111 TPVHSSTG-SPRTTLSPAGSTTRQGESTTFQSWPSSKDTMPAPPTTTSAFVELSTTSHGS 1169
Query: 1928 SEDSERWSGSASRNHLGSAWEQSRDGSRHPGSHHEDRAGHGHSADSSRQSGTRHTESSSR 1987
SAS G + E + S ++ +S H SS
Sbjct: 1170 PSSIPTTHFSASSTTFGRSEESTTVHSSPVAPATTPSPARSTTSGLVEESTAYH---SSP 1226
Query: 1988 GQAASSHEQARSSAGERHGSHHQLQSADSSRHSGIGHGQASSAVRDSGHRGYSGSQASDS 2047
G + H S+A R S S S+ H+ +SA+ + Y S S +
Sbjct: 1227 GSTQTMHFPESSTASGR--SEESRTSHSSTTHTISSPPSTTSALVEE-PTSYHSSPGSIA 1283
Query: 2048 EGHSEDSDTQSVSAQGKAGPHQQSHKE---------SARGQSGESSGRSGSFLYQVSTHE 2098
H +S T S ++ H + G+ ES+ S +T
Sbjct: 1284 TTHFPESSTTSGRSEESTASHSSPDTNGITPLPAHFTTSGRIAESTTFYISPGSMETTLA 1343
Query: 2099 QSESTHGQSAPSTGGRQGSHYDQAQDSSRHSASQEGQDTIRGHPGPSRGGRQGSHQEQSV 2158
+ +T G SA ST S ++ D + AS +I G P
Sbjct: 1344 STATTPGLSAKSTILYSSS---RSPDQTLSPASMT-SSSISGEP---------------- 1383
Query: 2159 DRSGHSGSHHSHTTSQGRSDASRGQSGSRSASRKTYDKEQSGDGSRHSGSHHHEASSWAD 2218
S +S + +HTT+ AS SG S + K S + + GS + +
Sbjct: 1384 -TSLYSQAESTHTTA---FPASTTTSGLSQESTTFHSKPGSTETTLSPGSITTSSFAQEF 1439
Query: 2219 SSRHSLVGQGQSS-GPRTSRPRGSSVSQDSDSEGHSEDSERRSGSASRNHHGSAQEQSRD 2277
++ HS G S+ P ++ G +S++S + S S + + N +QS
Sbjct: 1440 TTPHSQPGSALSTVSPASTTVPG--LSEESTTFYSSPGSTETTAFSHSNTMSIHSQQSTP 1497
Query: 2278 GSRHPRSHHEDRAGHGHSAESSRQSGTHHAENSSGGQAASSHEQARSSAGERHG 2331
P H + + ++S H+ + + G ++ ARS+A + G
Sbjct: 1498 FPDSPGFTHTVLPATLTTTDIGQESTAFHSSSDATG---TTPLPARSTASDLVG 1548
Score = 56.2 bits (134), Expect = 6e-07
Identities = 183/830 (22%), Positives = 284/830 (34%), Gaps = 147/830 (17%)
Query: 3251 SRHPRSHHEDRAGHGHSADRSRQSGTRHAETSSGGQAASSHEQARSSPGERHGSRHQQSA 3310
+R + ++R S D S + T+H ET S Q S + SA
Sbjct: 42 ARAAGAREKERQEVSSSPDVSELTATKHEETVINHSTFSGFSQITGSTVNTSIGGNTTSA 101
Query: 3311 DSSRHSGIPRGQASSAVRDSRHWGSSGSQ----ASDSEGHSEESDTQSVSGHGQAG---- 3362
+ S + V + GS+ ++ +S + GHSEES T S SG G G
Sbjct: 102 STPSSSDPFTTFSDYGVSVTFITGSTATKHFLDSSTNSGHSEES-TVSHSGPGATGTTLF 160
Query: 3363 ----------------PHQQSHQESAR----DRSGGRSGRSGSFLYQVSTHEQSESAHGR 3402
P + E+ + G S +S +F + +++ S R
Sbjct: 161 PSHSATSVFVGEPKTSPITSASMETTALPGSTTTAGLSEKSTTFYSSPRSPDRTLSP-AR 219
Query: 3403 TRTSTGRRQGSHHEQARDSSRHSASQEGQDTIRGHPGSSRRGRQGSHYEQSVDRSGHSGS 3462
T TS+G + S +R H+ + T+ PG S+ S D + G+
Sbjct: 220 T-TSSGVSEKSTTSHSRPGPTHTIAFPDSTTM---PGVSQESTASHSIPGSTDTTLSPGT 275
Query: 3463 -------------HHS-----------HTTSQGRSDASRGQSGSRSASRQTRNDEQS--- 3495
H S +TT+ G +AS S + T + S
Sbjct: 276 TTPSSLGPESTTFHSSPGYTKTTRLPDNTTTSGLLEASTPVHSSTGSPHTTLSPASSTTH 335
Query: 3496 -GDGSR-HSWSHHHEASTQADSSRHSQSGQGQSAGPRTSRNQGSSVSQDSDSQGHSEDSE 3553
G+ + SW + S + + + S + S S + GHSE+S
Sbjct: 336 EGEPTTFQSWPSSKDTSPAPSGTTSAFVKLSTTYHSSPSSTPTTHFSASSTTLGHSEEST 395
Query: 3554 RWSGSA---------SRNHRGSAQEQSRDGSRHPTSHH-----EDRAGHGHSAESSRQSG 3599
S +R+ E+S R P S E GHS ES+ G
Sbjct: 396 PVHSSPVATATTPPPARSATSGHVEESTAYHRSPGSTQTMHFPESSTTSGHSEESATFHG 455
Query: 3600 --THHAENSSGGQAASSHEQARSSAGERHGSHHQQSADSSRHSGIGHGQASSAVRDSGHR 3657
TH ++ AA +H SS G +H + S+ S S SS +
Sbjct: 456 STTHTKSSTPSTTAALAHTSYHSSLGSTETTHFRDSSTISGRSEESKASHSSPDAMATTV 515
Query: 3658 GSSGSQASDSEGHSEDSDTQSVSAHGQAGPHQQSHQESTRGRSAGRSGRSGSFLYQVSTH 3717
+GS S G S S S S A P + G S +S +F S+
Sbjct: 516 LPAGSTPSVLVGDSTPSPISSGSMETTALPGSTT--------KPGLSEKSTTF---YSSP 564
Query: 3718 EQSESAHGRAG-PSTGGRQGSRHEQARDSSRHSASQEGQDTIRGHPGSRRGGRQGSYHEQ 3776
++ H A S+G + S +R S H+ + G T+ G ++
Sbjct: 565 RSPDTTHLPASMTSSGVSEESTTSHSRPGSTHTTAFPGSTTMPG------------LSQE 612
Query: 3777 SVDRSGHSGSHHSHTT-SQGRSDAS---------HGQSGSRSASRETRNEEQSG--DGSR 3824
S + HS + TT S G + AS H + GS + N SG + S
Sbjct: 613 ST--ASHSSPGPTDTTLSPGSTTASSLGPEYTTFHSRPGSTETTLLPDNTTASGLLEASM 670
Query: 3825 --HSGSR--HHEASTQADSSRHSQSGQGESAGSRRSRRQGSSVSQDSDSEAYPEDSERRS 3880
HS +R H S ++R +S S S R + + E P + S
Sbjct: 671 PVHSSTRSPHTTLSPAGSTTRQGESTTFHSWPSSNDTRPAPPTTTSAFVE--PSTTSHGS 728
Query: 3881 ESASRNHHGSSR-------EQSRDGSRHPGSS------HRDTASHVQSSPVQSDSSTAKE 3927
S+ H S+R E+S PGS+ DT S S SST
Sbjct: 729 PSSIPTTHISARSTTSGLVEESTTYHSSPGSTQTMHFPESDTTSGRGEESTTSHSSTTHT 788
Query: 3928 HGHFSS-----LSQDSAYHSGIQSRGSPHSSSSYHYQSEGTERQKGQSGL 3972
S + + ++YHS SP S+++ H+ T + + +
Sbjct: 789 ISSAPSTTSALVEEPTSYHS------SPGSTATTHFPDSSTTSGRSEESI 832
>gi|78190492 retinitis pigmentosa GTPase regulator isoform C [Homo
sapiens]
Length = 1152
Score = 87.4 bits (215), Expect = 3e-16
Identities = 92/556 (16%), Positives = 178/556 (32%), Gaps = 40/556 (7%)
Query: 416 GSSGSQASDSEGHSENSDTQSVSGHGKAGLRQQSHQESTRGRSGERSGRSGSSLYQVSTH 475
G+ S+ + E ++ ++V HG + + + ++ G++ S
Sbjct: 592 GAEDSKGNGIEEQEVEANEENVKVHGGRKEKTEILSDDLTDKAEVSEGKAKS------VG 645
Query: 476 EQPDSAHGR-TGTSTGGRQGSHHEQ-------ARDSSRHSASQEGQDTIRGHPGSSRGGR 527
E D GR GT G G+ H Q +D R + G+ R
Sbjct: 646 EAEDGPEGRGDGTCEEGSSGAEHWQDEEREKGEKDKGRGEMERPGEGEKELAEKEEWKKR 705
Query: 528 QGSHHEQSVNRSGHSGSHHSHTTSQGRSDASHG--QSGSRSASRQTRNE-EQSGDGTRHS 584
G EQ GH + G + G + G R + E ++ G+G
Sbjct: 706 DGEEQEQKEREQGHQKERNQEMEEGGEEEHGEGEEEEGDREEEEEKEGEGKEEGEGEEVE 765
Query: 585 GSRHHEASSQADSSRHSQVGQGQSSGPRTSRNQGSSVSQDSDSQG-HSEDSERWSGSASR 643
G R E + R + +G+ G +QG ++++ +G E+ G
Sbjct: 766 GEREKEEGERKKEERAGKEEKGEEEG-----DQGEGEEEETEGRGEEKEEGGEVEGGEVE 820
Query: 644 NHHGSAQEQSRDGSRHPRSHHEDRAGHGHSADSSRKSGTRHTQNSSSGQAASSHEQARSS 703
G +E+ +G E+ G G + + + G+ E+
Sbjct: 821 EGKGEREEEEEEG------EGEEEEGEGEEEEGEGEEEEGEGKGEEEGEEGEGEEEGEEG 874
Query: 704 AGERHGSRHQLQSADSSRHSGTGHGQASSAVRDSGHRGSSGSQATDSEGHSEDSDTQSVS 763
GE + + G G G+ + G + + EG E+ +
Sbjct: 875 EGE----GEEEEGEGEGEEEGEGEGEEEEGEGEGEEEGEGEGEEEEGEGKGEEEGEE--- 927
Query: 764 GHGQAGHHQQSHQESARDRSGERSRRSGSFLYQVSTHKQSESSHGWTGPSTGVRQGSHHE 823
G+ ++ + D GE G + + + G G +G E
Sbjct: 928 --GEGEGEEEEGEGEGEDGEGEGEEEEGEWEGEEEEGEGEGEEEGEGEGEEGEGEGEEEE 985
Query: 824 QARDNSRHSASQDGQDTIRGHPGSSRRGRQGSHHEQSVDRSGHSGSHHSHTTSQGRSDAS 883
+ ++G++ G G + E + G G
Sbjct: 986 GEGEGEEEEGEEEGEEEGEGEEEGEGEGEEEEEGEVEGEVEGEEGEGEGEEEEGEEEGEE 1045
Query: 884 RGQSGSRSASRTTRNEEQSRDGS-RHSGSRHHEASSHADISRHSQAGQGQSEGS-RTSRR 941
R + G +R R EE+ +G + +G +E + + S+ G +T ++
Sbjct: 1046 REKEGEGEENRRNREEEEEEEGKYQETGEEENERQDGEEYKKVSKIKGSVKYGKHKTYQK 1105
Query: 942 QGSSVSQDSDSEGHSE 957
+ + +Q + E S+
Sbjct: 1106 KSVTNTQGNGKEQRSK 1121
Score = 85.1 bits (209), Expect = 1e-15
Identities = 87/517 (16%), Positives = 158/517 (30%), Gaps = 44/517 (8%)
Query: 1527 RSDASHGQSGPRSASRQTRNEEQSGDGSRH---SGSRHHEPSTRAGSSRHSQVGQGESAG 1583
+++ S G++ +S E GDG+ SG+ H + R + G+ E G
Sbjct: 633 KAEVSEGKA--KSVGEAEDGPEGRGDGTCEEGSSGAEHWQDEEREKGEKDKGRGEMERPG 690
Query: 1584 S---------KTSRRQGSSVSQDRDSEGHSEDSERRSESASRNHYGSAREQSRHGSRNPR 1634
+ +R G Q +GH ++ + E +G E+ R
Sbjct: 691 EGEKELAEKEEWKKRDGEEQEQKEREQGHQKERNQEMEEGGEEEHGEGEEEE-----GDR 745
Query: 1635 SHQEDRASHG-HSAESSRQSGTRHAETSSGGQAASSQEQARSSPGERHGSRHQQSADSST 1693
+E++ G E G R E G+ + + GE G + + + +
Sbjct: 746 EEEEEKEGEGKEEGEGEEVEGEREKEE---GERKKEERAGKEEKGEEEGDQGEGEEEETE 802
Query: 1694 DSGTGRRQDSSVVGDSGNRGSSGSQASDSEGHSEESDTQSVSAHGQAGPHQQSHQESTRG 1753
G + + V G G + + EG EE + + G+ + + G
Sbjct: 803 GRGEEKEEGGEVEGGEVEEGKGEREEEEEEGEGEEEEGEGEEEEGEGEEEEGEGKGEEEG 862
Query: 1754 Q--SGERSGRSGSFLYQVSTHEQSESAHGRTGPSTGGRQRSRHEQARDSSRHSASQEGQD 1811
+ GE G G E+ E G G + E + +EG+
Sbjct: 863 EEGEGEEEGEEGE---GEGEEEEGEGEGEEEGEGEGEEEEGEGEGEEEGEGEGEEEEGEG 919
Query: 1812 TIRGHPGSSRGGRQGSHYEQSVDSSGHSGSHHSHTTSQERSDVSRGQSGSRSVSRQTRNE 1871
+G G +G E+ + G G E G + E
Sbjct: 920 --KGEEEGEEG--EGEGEEEEGEGEGEDGEGEGEEEEGEWEGEEEEGEGEGEEEGEGEGE 975
Query: 1872 KQSGDGSRHSGSRHHEASSRADSSRHSQVGQGQSSGPRTSRNQGSSVSQDSDSQGHSEDS 1931
+ G+G G E + G+ + G +G + +G E
Sbjct: 976 EGEGEGEEEEGEGEGEEEEGEEEGEEEGEGEEEGEGEGEEEEEGEVEGEVEGEEGEGEGE 1035
Query: 1932 ERWSGSASRNHLGSAWEQSRDGSRHPGSHHEDRAGHGHSADSSRQSGTRHTESSSRGQAA 1991
E G E+ +G + + E+ G ++ E + R
Sbjct: 1036 EE-----EGEEEGEEREKEGEGEENRRNREEEEEEEGKYQETGE-------EENERQDGE 1083
Query: 1992 SSHEQARSSAGERHGSHHQLQSADSSRHSGIGHGQAS 2028
+ ++ ++G H Q + G G Q S
Sbjct: 1084 EYKKVSKIKGSVKYGKHKTYQKKSVTNTQGNGKEQRS 1120
Score = 81.6 bits (200), Expect = 1e-14
Identities = 95/528 (17%), Positives = 159/528 (30%), Gaps = 54/528 (10%)
Query: 1198 TTSQGRSDASHGQSGSRSASRQTRKDKQSGDGSRHSGSRHHEAASWADSSRHSQVGQEQS 1257
T +G S A H Q R KDK G+ R G E A + + G+EQ
Sbjct: 658 TCEEGSSGAEHWQDEEREKGE---KDKGRGEMER-PGEGEKELAEKEEWKKRD--GEEQE 711
Query: 1258 SGSRTSRHQGSSVSQDSDSERHSDDSERLSGSASRNHHGSSREQSRDGSRHPGFHQEDRA 1317
R HQ ER+ + E E+ +G G +E+
Sbjct: 712 QKEREQGHQ---------KERNQEMEE------------GGEEEHGEGEEEEGDREEEEE 750
Query: 1318 SHGHSADSSRQSGTHHTESSSHGQAVSSHEQARSSPGERHGSRHQQSADSSRHSGIGHRQ 1377
G + G+ + GE G + + + + G +
Sbjct: 751 KEGEGKEEGEGEEVEGEREKEEGERKKEERAGKEEKGEEEGDQGEGEEEETEGRGEEKEE 810
Query: 1378 ASSAVRDSGHRGSSGSQVTNSEGHSEDSDTQSVSAHGQAGPHQQSHKESARGQSGESSGR 1437
G + EG E+ + + G+ + K G+ GE
Sbjct: 811 GGEVEGGEVEEGKGEREEEEEEGEGEEEEGEGEEEEGEGEEEEGEGKGEEEGEEGEGEEE 870
Query: 1438 SRSFLYQVSSHEQSESTHGQTAPSTGGRQGSRHEQARNSSRHSASQDGQDTIRGHPGSSR 1497
+ E G+ G E+ +G++ G
Sbjct: 871 GE------EGEGEGEEEEGEGEGEEEGEGEGEEEEGEGEGEEEGEGEGEEEEGEGKGEEE 924
Query: 1498 GGR-QGSYHEQSVDRSGHSGYHHSHTTPQGRSDASHGQ-SGPRSASRQTRNEEQSGDGSR 1555
G +G E+ + G G +G + G+ G EE G+G
Sbjct: 925 GEEGEGEGEEEEGEGEGEDG--------EGEGEEEEGEWEGEEEEGEGEGEEEGEGEGEE 976
Query: 1556 HSGSRHHEPSTRAGSSRH-SQVGQGESAGSKTSRRQGSSVSQ-DRDSEGHSEDSERRSES 1613
G E G + G+ E G + +G + + + E E+ E E
Sbjct: 977 GEGEGEEEEGEGEGEEEEGEEEGEEEGEGEEEGEGEGEEEEEGEVEGEVEGEEGEGEGEE 1036
Query: 1614 ASRNHYGSAREQSRHGSRNPRSHQEDRASHGHSAESSRQSGTRHAETSSGGQAASSQEQA 1673
G RE+ G N R+ +E+ G E+ + R G+ +
Sbjct: 1037 EEGEEEGEEREKEGEGEENRRNREEEEEEEGKYQETGEEENER-----QDGEEYKKVSKI 1091
Query: 1674 RSSPGERHGSRHQQSADSSTDSGTGRRQDSSVVGDSG---NRGSSGSQ 1718
+ S +Q+ + ++T G G+ Q S + S G SGS+
Sbjct: 1092 KGSVKYGKHKTYQKKSVTNT-QGNGKEQRSKMPVQSKRLLKNGPSGSK 1138
Score = 80.5 bits (197), Expect = 3e-14
Identities = 86/488 (17%), Positives = 156/488 (31%), Gaps = 55/488 (11%)
Query: 95 PISGHKHRKHSHHDKHEDNKQEENKENRKRPSSLERRNNRKGNKGRSKSPRETGGKRHES 154
P G K K D +++E KE E+ + ++ N+ + E G+ E
Sbjct: 689 PGEGEKELAEKEEWKKRDGEEQEQKER-------EQGHQKERNQEMEEGGEEEHGEGEEE 741
Query: 155 SSEKKERKGYSPTHREEEYGKNHHNSS----KKEKNKTENTRLGDNRKRLSERLEEKEDN 210
+++E EE+ G+ + E+ K E R + R E+ EE+ D
Sbjct: 742 EGDREEE--------EEKEGEGKEEGEGEEVEGEREKEEGERKKEERAGKEEKGEEEGDQ 793
Query: 211 EEGVYDYENTGRMTQKWIQSGHIATYYTIQDEAYDTTDSLLEENKIYERSRSSDGKSSSQ 270
EG + E GR +K +E + +EE K +G+ +
Sbjct: 794 GEG-EEEETEGRGEEK--------------EEGGEVEGGEVEEGKGEREEEEEEGEGEEE 838
Query: 271 VNRSRHENTSQVPLQESRTRKRRGSRVSQDRDSEGH-SEDSERHSGSASRNHHGSAWEQS 329
E E + G ++ EG E+ E G E+
Sbjct: 839 EGEGEEE--------EGEGEEEEGEGKGEEEGEEGEGEEEGEEGEGEGEEEEGEGEGEEE 890
Query: 330 RDGSRHPRSHDEDRASHGHSADSSRQSGTRHAETSSRGQTASSHEQARSSPGERHGSGHQ 389
+G + + G + + E G+ E+ + G G +
Sbjct: 891 GEGEGEEEEGEGEGEEEGEGEGEEEEGEGKGEEEGEEGEGEGEEEEGEGEGEDGEGEGEE 950
Query: 390 QSADSSRHSATGRGQASSAVSDRGHRGSSGSQASDSEGHSENSDTQ---SVSGHGKAGLR 446
+ + G G+ G G + + EG E + + G G+
Sbjct: 951 EEGEWEGEEEEGEGEGEEEGEGEGEEGEGEGEEEEGEGEGEEEEGEEEGEEEGEGEEEGE 1010
Query: 447 QQSHQESTRGRSGERSGRSGSSLYQVSTHEQPDSAHGRTGTSTGGRQGSHHEQARDSSRH 506
+ +E GE G G + E+ + G R+ E+ +
Sbjct: 1011 GEGEEEEEGEVEGEVEGEEGEGEGEEEEGEEEGEEREKEGEGEENRRNREEEEEEEGKYQ 1070
Query: 507 SASQEGQDTIRGH--------PGSSRGGRQGSHHEQSV-NRSGHSGSHHSHTTSQGRSDA 557
+E + G GS + G+ ++ ++SV N G+ S Q +
Sbjct: 1071 ETGEEENERQDGEEYKKVSKIKGSVKYGKHKTYQKKSVTNTQGNGKEQRSKMPVQSKRLL 1130
Query: 558 SHGQSGSR 565
+G SGS+
Sbjct: 1131 KNGPSGSK 1138
Score = 79.7 bits (195), Expect = 5e-14
Identities = 99/585 (16%), Positives = 183/585 (31%), Gaps = 59/585 (10%)
Query: 3334 GSSGSQASDSEGHSEESDTQSVSGHGQAGPHQQSHQESARDRSGGRSGRSGSFLYQVSTH 3393
G+ S+ + E E++ ++V HG + + D++ G++ S V
Sbjct: 592 GAEDSKGNGIEEQEVEANEENVKVHGGRKEKTEILSDDLTDKAEVSEGKAKS----VGEA 647
Query: 3394 EQSESAHGRTRTSTGRRQGSHHEQA------RDSSRHSASQEGQDTIRGHPGSSRRGRQG 3447
E G G H + +D R + G+ + R G
Sbjct: 648 EDGPEGRGDGTCEEGSSGAEHWQDEEREKGEKDKGRGEMERPGEGEKELAEKEEWKKRDG 707
Query: 3448 SHYEQSVDRSGHSGSHHSHTTSQGRSDASRGQS--GSRSASRQTRND-EQSGDGSRHSWS 3504
EQ GH + G + G+ G R + + ++ G+G
Sbjct: 708 EEQEQKEREQGHQKERNQEMEEGGEEEHGEGEEEEGDREEEEEKEGEGKEEGEGEEVEGE 767
Query: 3505 HHHEASTQADSSRHSQSGQGQSAGPRTSRNQGSSVSQDSDSQGHS-EDSERWSGSASRNH 3563
E + R + +G+ G +QG ++++ +G E+ G
Sbjct: 768 REKEEGERKKEERAGKEEKGEEEG-----DQGEGEEEETEGRGEEKEEGGEVEGGEVEEG 822
Query: 3564 RGSAQEQSRDGS-RHPTSHHEDRAGHGHSAESSRQSGTHHAENSSGGQAASSHEQARSSA 3622
+G +E+ +G E+ G G E + G+ E+
Sbjct: 823 KGEREEEEEEGEGEEEEGEGEEEEGEGEEEEG-------EGKGEEEGEEGEGEEEGEEGE 875
Query: 3623 GERHGSHHQQSADSSRHSGIGHGQASSAVRDSGHRGSSGSQASDSEGHSEDSDTQSVSAH 3682
GE ++ G G G+ + G + + EG E+
Sbjct: 876 GE---GEEEEGEGEGEEEGEGEGEEEEGEGEGEEEGEGEGEEEEGEGKGEEE-------- 924
Query: 3683 GQAGPHQQSHQESTRGRSAGRSGRSGSFLYQVSTHEQSESAHGRAGPSTGGRQGSRHEQA 3742
G + E G G G + + E G G G +G E
Sbjct: 925 ---GEEGEGEGEEEEGEGEGEDGEGEGEEEEGEWEGEEEEGEGE-GEEEGEGEGEEGE-- 978
Query: 3743 RDSSRHSASQEGQDTIRGHPGSRRGGRQGSYHEQSVDRSGHSGSHHSHTTSQGRSDASHG 3802
+EG+ G G +G E+ G +G + G
Sbjct: 979 ----GEGEEEEGEGEGEEEEGEEEGEEEGEGEEEGEG----EGEEEEEGEVEGEVEGEEG 1030
Query: 3803 QSGSRSASRETRNEEQSGDGSRHSGSRHHEASTQADSSRHSQSGQGESAGSRRSRRQGSS 3862
+ E EE+ +G R+ E + + ++ ++G+ E+ R+ +
Sbjct: 1031 EGEGEEEEGEEEGEEREKEGEGEENRRNRE-EEEEEEGKYQETGEEEN--ERQDGEEYKK 1087
Query: 3863 VSQDSDSEAYPEDSERRSESASRNHHGSSREQSRDGSRHPGSSHR 3907
VS+ S Y + + +S + N G+ +EQ S+ P S R
Sbjct: 1088 VSKIKGSVKYGKHKTYQKKSVT-NTQGNGKEQR---SKMPVQSKR 1128
Score = 77.8 bits (190), Expect = 2e-13
Identities = 91/575 (15%), Positives = 175/575 (30%), Gaps = 52/575 (9%)
Query: 1871 EKQSGDGSRHSGSRHHEASSRADSSRHSQVGQGQSSGPRTSRNQGSSVSQD-SDSQGHSE 1929
EK+ + S+ +G E + ++ + + ++ + VS+ + S G +E
Sbjct: 589 EKEGAEDSKGNGIEEQEVEANEENVKVHGGRKEKTEILSDDLTDKAEVSEGKAKSVGEAE 648
Query: 1930 DSERWSGSASRNHLGSAWEQSRDGSRHPGSHHEDRAGHGHSADSSRQSGTRHTESSSRGQ 1989
D G + S E +D R G + R + ++ + G+
Sbjct: 649 DGPEGRGDGTCEEGSSGAEHWQDEEREKGEKDKGRGEMERPGEGEKELAEKEEWKKRDGE 708
Query: 1990 AASSHEQARSSAGERHGSHHQLQSADSSRHSGIGHGQASSAVRDSGHRGYSGSQASDSEG 2049
EQ G + + +++ H G G+ R+ + + EG
Sbjct: 709 ---EQEQKEREQGHQKERNQEMEEGGEEEH---GEGEEEEGDREE-------EEEKEGEG 755
Query: 2050 HSEDSDTQSVSAQGKAGPHQQSHKESARGQSGESSGRSGSFLYQVSTHEQSESTHGQSAP 2109
E + + K ++ + + + + GE G G E+ G+
Sbjct: 756 KEEGEGEEVEGEREKEEGERKKEERAGKEEKGEEEGDQG------EGEEEETEGRGEEKE 809
Query: 2110 STGGRQGSHYDQAQDSSRHSASQEGQDTIRGHPGPSRGGRQGSHQEQSVDRSGHSGSHHS 2169
G +G ++ + R +EG+ G G + + + G
Sbjct: 810 EGGEVEGGEVEEGK-GEREEEEEEGE-------GEEEEGEGEEEEGEGEEEEGEGKGEEE 861
Query: 2170 HTTSQGRSDASRGQ-SGSRSASRKTYDKEQSGDGSRHSGSHHHEASSWADSSRHSLVGQG 2228
+G + G+ G ++E G+G G E + G+G
Sbjct: 862 GEEGEGEEEGEEGEGEGEEEEGEGEGEEEGEGEGEEEEGEGEGEEEGEGEGEEEEGEGKG 921
Query: 2229 QSSGPRTSRPRGSSVSQDSDSEGHSEDSERRSGSASRNHHGSAQEQSRDGSRHPRSHHED 2288
+ G G ++ + EG ED E G +E +G E+
Sbjct: 922 EEEG-----EEGEGEGEEEEGEGEGEDGEGEGEEEEGEWEGEEEEGEGEGEEEGEGEGEE 976
Query: 2289 RAGHGH----SAESSRQSGTHHAENSSGGQAASSHEQARSSAGERHGSHHQQSADSSRHS 2344
G G E + G E G+ E GE G +
Sbjct: 977 GEGEGEEEEGEGEGEEEEGEEEGEEEGEGEEEGEGEGEEEEEGEVEG-------EVEGEE 1029
Query: 2345 GIGHGQASSAVRDSGHRGSSGSQASDSEGHSEDSDTQSVSAHGQAGPHQQSHQESTRGRS 2404
G G G+ + R G + E+ + + + + G + Q+ +
Sbjct: 1030 GEGEGEEEEGEEEGEEREKEGEGEENRRNREEEEEEE--GKYQETGEEENERQDGEEYKK 1087
Query: 2405 AGRSGRSGSFLYQVSTHEQSESAHGRTGTSTGGRQ 2439
+ GS Y Q +S T T G++
Sbjct: 1088 VSKI--KGSVKYGKHKTYQKKSV---TNTQGNGKE 1117
Score = 77.4 bits (189), Expect = 3e-13
Identities = 101/591 (17%), Positives = 177/591 (29%), Gaps = 76/591 (12%)
Query: 1222 KDKQSGDGSRHSGSRHHEAASWADS--------SRHSQVGQEQSSGSRTSRHQGSSVSQD 1273
++K+ + S+ +G E + ++ + + + + + S + SV +
Sbjct: 588 EEKEGAEDSKGNGIEEQEVEANEENVKVHGGRKEKTEILSDDLTDKAEVSEGKAKSVGEA 647
Query: 1274 SDSERHSDDSERLSGSASRNHHGSSREQSRDGSRHPGFHQEDRASHGHSADSSRQSGTHH 1333
D D GS+ H E+ G + G + +R G + ++
Sbjct: 648 EDGPEGRGDGTCEEGSSGAEHWQD--EEREKGEKDKGRGEMERPGEGEKELAEKEEWKKR 705
Query: 1334 T-ESSSHGQAVSSHEQARSSPGERHGSRHQQSADSSRHSGIGHRQASSAVRDSGHRGSSG 1392
E + H++ R+ E G + G R+ G G
Sbjct: 706 DGEEQEQKEREQGHQKERNQEMEEGGEEEHGEGEEEE----GDREEEEEKEGEGKEEGEG 761
Query: 1393 SQVTNSEGHSEDSDTQSVSAHGQAGPHQQSHKESARGQSGESSGRSRSFLYQVSSHEQSE 1452
+V EG E + + +AG ++ +E +G+ E R E+
Sbjct: 762 EEV---EGEREKEEGERKKEE-RAGKEEKGEEEGDQGEGEEEETEGRG-----EEKEEGG 812
Query: 1453 STHGQTAPSTGGRQGSRHEQARNSSRHSASQDGQDTIRGHPGSSRGGRQGSYHEQSVDRS 1512
G G + E+ ++ + G +G +G E +
Sbjct: 813 EVEGGEVEEGKGEREEEEEEGEGEEEEGEGEEEEGEGEEEEGEGKGEEEGE--EGEGEEE 870
Query: 1513 GHSGYHHSHTTPQGRSDASHGQSGPRSASRQTRNEEQSGDGSRHSGSRHHEPSTRAGSSR 1572
G G +G + G+ EE G+G G E
Sbjct: 871 GEEG--------EGEGEEEEGEG--------EGEEEGEGEGEEEEGEGEGEEEGEGEGEE 914
Query: 1573 HSQVGQGESAGSKTSRRQGSSVSQDRDSEGHSEDSERRSESASRNHYGSAREQSRHGSRN 1632
G+GE G +G ++ + EG ED E E G E G
Sbjct: 915 EEGEGKGEEEGE-----EGEGEGEEEEGEGEGEDGEGEGEEEEGEWEGEEEEGEGEGEEE 969
Query: 1633 PRSHQEDRASHGHSAESSRQSGTRHAETSSGGQAASSQEQARSSPGERHGSRHQQSADSS 1692
E+ G E + +E+ GE G ++
Sbjct: 970 GEGEGEEGEGEGEEEEGEGEG----------------EEEEGEEEGEEEGEGEEEGEGEG 1013
Query: 1693 TDSGTGRRQDSSVVGDSG------NRGSSGSQASDSEGHSEESDTQSVSAHGQAGPHQQS 1746
+ G + V G+ G G + + EG EE+ + G +Q++
Sbjct: 1014 EEEEEG-EVEGEVEGEEGEGEGEEEEGEEEGEEREKEGEGEENRRNREEEEEEEGKYQET 1072
Query: 1747 HQESTRGQSGER----SGRSGSFLYQVSTHEQSESAHGRTGPSTGGRQRSR 1793
+E Q GE S GS Y Q +S G G QRS+
Sbjct: 1073 GEEENERQDGEEYKKVSKIKGSVKYGKHKTYQKKSVTNTQG--NGKEQRSK 1121
Score = 77.4 bits (189), Expect = 3e-13
Identities = 101/631 (16%), Positives = 196/631 (31%), Gaps = 95/631 (15%)
Query: 3369 QESARDRSGGRSGRSGSFLYQVSTHEQSESAHGRTRTSTGRRQGSHHEQARDSSRHSASQ 3428
+E A D G +G +V +E++ HG + T ++A S + S
Sbjct: 590 KEGAEDSKG-----NGIEEQEVEANEENVKVHGGRKEKTEILSDDLTDKAEVSEGKAKSV 644
Query: 3429 -EGQDTIRGH-PGSSRRGRQGSHYEQSVDRSGHSGSHHSHTTSQGRSDASRGQSGSRSAS 3486
E +D G G+ G G+ + Q +R +GR + R G + +
Sbjct: 645 GEAEDGPEGRGDGTCEEGSSGAEHWQDEERE-------KGEKDKGRGEMERPGEGEKELA 697
Query: 3487 RQT---RNDEQSGDGSRHSWSHHHEASTQADSSRHSQSGQGQSAGPRTSRNQGSSVSQDS 3543
+ + D + + H E + + + + G+G+ +
Sbjct: 698 EKEEWKKRDGEEQEQKEREQGHQKERNQEMEEGGEEEHGEGEEEEGDREEEEEKEGEGKE 757
Query: 3544 DSQGHSEDSERWS--GSASRNHRGSAQEQSRDGSRHPTSHHEDRAGHGHSAESSRQSGTH 3601
+ +G + ER G + R +E+ + E+ G G E + G
Sbjct: 758 EGEGEEVEGEREKEEGERKKEERAGKEEKGEEEGDQGEGEEEETEGRG---EEKEEGGEV 814
Query: 3602 HAENSSGGQAASSHEQARSSAGERHGSHHQQSADSSRHSGIGHGQASSAVRDSGHRGSSG 3661
G+ E+ E G ++ + G G G+ + G G
Sbjct: 815 EGGEVEEGKGEREEEEEEGEGEEEEGEGEEEEGEGEEEEGEGKGE------EEGEEGEGE 868
Query: 3662 SQASDSEGHSEDSDTQSVSAHGQAGPHQQSHQESTRGRSAGRSGRSGSFLYQVSTHEQSE 3721
+ + EG E+ + + G+ + E G G G + E
Sbjct: 869 EEGEEGEGEGEEEEGE-----GEGEEEGEGEGEEEEGEGEGEEEGEG----------EGE 913
Query: 3722 SAHGRAGPSTGGRQGSRHEQARDSSRHSASQEGQDTIRGHPGSRRGGRQGSYHEQSVDRS 3781
G +G E+ + +EG+ G G +G E+ +
Sbjct: 914 EEEG---------EGKGEEEGEEGEGEGEEEEGEG--EGEDG------EGEGEEEEGEWE 956
Query: 3782 GHSGSHHSHTTSQGRSDASHGQSGSRSASRETRNEEQSGDGSRHSGSRHHEASTQADSSR 3841
G +G + G+ E EE G+G G E
Sbjct: 957 GEEEEGEGEGEEEGEGEGEEGEG-------EGEEEEGEGEGEEEEGEEEGE--------- 1000
Query: 3842 HSQSGQGESAGSRRSRR------QGSSVSQDSDSEAYPEDSERRSESASRNHHGSSREQS 3895
+ G+GE G +G ++ + E E+ E E + G ++
Sbjct: 1001 --EEGEGEEEGEGEGEEEEEGEVEGEVEGEEGEGEGEEEEGEEEGEEREKEGEGEENRRN 1058
Query: 3896 RDGSRHPGSSHRDTASHVQSSPVQSDSSTAKEHGHFSSLSQDSAY--HSGIQSRGSPHSS 3953
R+ +++T +++ +E+ S + Y H Q + ++
Sbjct: 1059 REEEEEEEGKYQETGEE------ENERQDGEEYKKVSKIKGSVKYGKHKTYQKKSVTNTQ 1112
Query: 3954 SSYHYQSEGTERQKGQSGLVWRHGSYGSADY 3984
+ E + QS + ++G GS +
Sbjct: 1113 GN---GKEQRSKMPVQSKRLLKNGPSGSKKF 1140
Score = 75.5 bits (184), Expect = 1e-12
Identities = 101/630 (16%), Positives = 194/630 (30%), Gaps = 56/630 (8%)
Query: 617 QGSSVSQDSDSQGHSEDSERWSGSASRNH--HGSAQEQSRDGSRHPRSHHEDRAGHGHSA 674
Q ++++++ DS + E SE G A + H G Q + A
Sbjct: 534 QDTALTENDDSDEYEEMSEMKEGKACKQHVSQGIFMTQPATTIEAFSDEEVEIPEEKEGA 593
Query: 675 DSSRKSGTRHTQNSSSGQAASSHEQARSSAGERHGSRHQLQSADSSRHSGTGHGQASSAV 734
+ S+ +G + ++ + H + + G +
Sbjct: 594 EDSKGNGIEEQEVEANEENVKVHGGRKEKTEILSDDLTDKAEVSEGKAKSVGEAEDGPEG 653
Query: 735 RDSG--HRGSSGS---QATDSEGHSEDSDTQSVSGHGQAGHHQQSHQESARDRSGE---- 785
R G GSSG+ Q + E +D + G+ G + + +E + R GE
Sbjct: 654 RGDGTCEEGSSGAEHWQDEEREKGEKDKGRGEMERPGE-GEKELAEKEEWKKRDGEEQEQ 712
Query: 786 RSRRSGSFLYQVSTHKQ----SESSHGWTGPSTGVRQGSHHEQARDNSRHSASQDGQDTI 841
+ R G +Q +++ E HG G R+ E+ + ++ +
Sbjct: 713 KEREQG---HQKERNQEMEEGGEEEHGEGEEEEGDRE-EEEEKEGEGKEEGEGEEVEGER 768
Query: 842 RGHPGSSRRGRQGSHHEQSVDRSGHSGSHHSHTTSQGRSDASRG--QSGSRSASRTTRNE 899
G ++ + E+ + T +G G + G + R E
Sbjct: 769 EKEEGERKKEERAGKEEKGEEEGDQGEGEEEETEGRGEEKEEGGEVEGGEVEEGKGEREE 828
Query: 900 EQSR-DGSRHSGSRHHEASSHADISRHSQAGQGQSEGSRTSRRQGSSVSQDSDSEGHSED 958
E+ +G G E + G+G+ EG +G ++ + EG E+
Sbjct: 829 EEEEGEGEEEEGEGEEE---EGEGEEEEGEGKGEEEG---EEGEGEEEGEEGEGEGEEEE 882
Query: 959 SERWSGSASRNHRGSAQEQSRHGSRHPRSHHEDRAGHGHSADSSRQSGTPHAETSSGGQA 1018
E G G +E G E+ G G + + E G+
Sbjct: 883 GE-GEGEEEGEGEGEEEEGEGEGEEEGEGEGEEEEGEGKGEEEGEEGEGEGEEEEGEGEG 941
Query: 1019 ASSHEQARSSPGERHGSRHQQSADSSRHSGIPRRQASSAVRDSGHWGSSGSQASDSEGHS 1078
+ GE G + + G + + EG
Sbjct: 942 EDGEGEGEEEEGEWEGEEEEGEGEGEEE------------------GEGEGEEGEGEGEE 983
Query: 1079 EESDTQSVSGHGQDGPHQQSHQESARDWSGGRSGRSGSFIYQVSTHEQSESAHGRTRTST 1138
EE + + G++ ++ E + G +V + E G
Sbjct: 984 EEGEGEGEEEEGEEEGEEEGEGEEEGEGEGEEEEEG-----EVEGEVEGEEGEGEGEEEE 1038
Query: 1139 GRRQGSHHE---QARDSSRHSASQEGQDTIRAHPGSRRGGRQGSHHEQSVDRSGHSGSHH 1195
G +G E + ++ R+ +E ++ G RQ + V + S +
Sbjct: 1039 GEEEGEEREKEGEGEENRRNREEEEEEEGKYQETGEEENERQDGEEYKKVSKIKGSVKYG 1098
Query: 1196 SHTTSQGRSDASHGQSGSRSASRQTRKDKQ 1225
H T Q +S + +G S+ + K+
Sbjct: 1099 KHKTYQKKSVTNTQGNGKEQRSKMPVQSKR 1128
Score = 75.5 bits (184), Expect = 1e-12
Identities = 100/628 (15%), Positives = 192/628 (30%), Gaps = 58/628 (9%)
Query: 2241 SSVSQDSDSEGHSEDSERRSGSASRNH--HGSAQEQSRDGSRHPRSHHEDRAGHGHSAES 2298
++++++ DS+ + E SE + G A + H G Q + AE
Sbjct: 536 TALTENDDSDEYEEMSEMKEGKACKQHVSQGIFMTQPATTIEAFSDEEVEIPEEKEGAED 595
Query: 2299 SRQSGTHHAENSSGGQAASSHEQARSSAGERHGSHHQQSADSSRHSGIGHGQASSAVRDS 2358
S+ +G E + + H G R S D + + + G+A S
Sbjct: 596 SKGNGIEEQEVEANEENVKVH-------GGRKEKTEILSDDLTDKAEVSEGKAKSV---- 644
Query: 2359 GHRGSSGSQASDSEGHSEDSDTQSVSAHGQAGPHQQSHQESTRGRSAGRSGRSGSFLYQV 2418
G EG + + + S ++ E +GR G R G ++
Sbjct: 645 ------GEAEDGPEGRGDGTCEEGSSGAEHWQDEEREKGEKDKGR--GEMERPGEGEKEL 696
Query: 2419 STHEQSESAHGRTGTSTGGRQGSHHKQARDSSRHSTSQEGQDTIHGHPGSSSGGRQGSHY 2478
+ E+ + G QG H K+ R+ +EG + HG G R+
Sbjct: 697 AEKEEWKKRDGEEQEQKEREQG-HQKE-----RNQEMEEGGEEEHGEGEEEEGDREEEEE 750
Query: 2479 EQLVDRSGHSGSHHSHTTSQGRSDASHGHSGSRSASRQTRNDEQSGDGSRHSGSRHHEAS 2538
++ + G + + + + D+ G+ G +
Sbjct: 751 KEGEGKEEGEGEEVEGEREKEEGERKKEERAGKEEKGEEEGDQGEGEEEETEGRGEEKEE 810
Query: 2539 SRADSSGHSQVGQGQSEGPRTSRNWGSSFSQDSDSQGHSEDSERWSGSASRNHHGSAQEQ 2598
G + G+G+ E + + +G E+ E G +E+
Sbjct: 811 GGEVEGGEVEEGKGEREEEEEEGEGEEEEGEGEEEEGEGEEEEGEGKGEEEGEEGEGEEE 870
Query: 2599 LRDGSRHPRSHQ-------------EDRAGHGHSADSSRQSGTRHTQTSSG------GQA 2639
+G + E+ G G + G G G+
Sbjct: 871 GEEGEGEGEEEEGEGEGEEEGEGEGEEEEGEGEGEEEGEGEGEEEEGEGKGEEEGEEGEG 930
Query: 2640 ASSHEQARSSAGERHGSHHQQSADSSRHSGIGHGQASSAVRDSGHRGYSGSQASDNEGHS 2699
E+ + G ++ + G G+ G G + + EG
Sbjct: 931 EGEEEEGEGEGEDGEGEGEEEEGEWEGEEEEGEGEGEEEGEGEGEEGEGEGEEEEGEGEG 990
Query: 2700 EDSDTQ---SVSAHGQAGSHQQSHQESARGRSGETSGHSGSFLYQVSTHEQSESSHGWTG 2756
E+ + + G+ + +E GE G G + E+ G
Sbjct: 991 EEEEGEEEGEEEGEGEEEGEGEGEEEEEGEVEGEVEGEEGEGEGEEEEGEEEGEEREKEG 1050
Query: 2757 PSTRGRQGSRHEQAQD------SSRHSASQDGQD--TIRGHPGSSRGGRQGYHHEHSV-D 2807
R+ E+ ++ + QDG++ + GS + G+ + + SV +
Sbjct: 1051 EGEENRRNREEEEEEEGKYQETGEEENERQDGEEYKKVSKIKGSVKYGKHKTYQKKSVTN 1110
Query: 2808 SSGHSGSHHSHTTSQGRSDASRGQSGSR 2835
+ G+ S Q + G SGS+
Sbjct: 1111 TQGNGKEQRSKMPVQSKRLLKNGPSGSK 1138
Score = 74.7 bits (182), Expect = 2e-12
Identities = 106/636 (16%), Positives = 198/636 (31%), Gaps = 85/636 (13%)
Query: 1590 QGSSVSQDRDSEGHSEDSERRSESASRNHYGSAREQSRHGSRNPRSHQEDRASHGHSAES 1649
Q ++++++ DS+ + E SE + A + H ++ + E E
Sbjct: 534 QDTALTENDDSDEYEEMSEMKEGKACKQHVSQGIFMTQPATTIEAFSDE---------EV 584
Query: 1650 SRQSGTRHAETSSGGQAASSQEQARSSPGERHGSRHQQSADSSTDSGTGRRQDSSVVGDS 1709
AE S G + +A + HG R +++ S D D + V +
Sbjct: 585 EIPEEKEGAEDSKGNGIEEQEVEANEENVKVHGGRKEKTEILSDDL-----TDKAEVSE- 638
Query: 1710 GNRGSSGSQASDSEGHSEESDTQSVSAHGQAGPHQQSHQESTRGQSGERSGRSGSFLYQV 1769
G S G EG RG G SG+ +Q
Sbjct: 639 GKAKSVGEAEDGPEG---------------------------RGDGTCEEGSSGAEHWQD 671
Query: 1770 STHEQSESAHGR---TGPSTGGRQRSRHEQARDSSRHSASQEGQDTIRGHPGSSRGGRQG 1826
E+ E GR P G ++ + E+ + R QE ++ +GH
Sbjct: 672 EEREKGEKDKGRGEMERPGEGEKELAEKEEWK--KRDGEEQEQKEREQGH---------- 719
Query: 1827 SHYEQSVDSSGHSGSHHSHTTSQERSDVSRGQSGSRSVSRQTRNE-KQSGDGSRHSGSRH 1885
++ + G H +E + G R + E K+ G+G G R
Sbjct: 720 ---QKERNQEMEEGGEEEHGEGEE-------EEGDREEEEEKEGEGKEEGEGEEVEGERE 769
Query: 1886 HEASSRADSSRHSQVGQGQSSGPRTSRNQGSSVSQDSDSQGHS-EDSERWSGSASRNHLG 1944
E R R + +G+ G +QG ++++ +G E+ G G
Sbjct: 770 KEEGERKKEERAGKEEKGEEEG-----DQGEGEEEETEGRGEEKEEGGEVEGGEVEEGKG 824
Query: 1945 SAWEQSRDGS-RHPGSHHEDRAGHGHSADSSRQSGTRHTESSSRGQAASSHEQARSSAGE 2003
E+ +G E+ G G + + E + + GE
Sbjct: 825 EREEEEEEGEGEEEEGEGEEEEGEGEEEEGEGKGEEEGEEGEGEEEGEEGEGEGEEEEGE 884
Query: 2004 RHGSHHQLQSADSSRHSGIGHGQASSAVRDSGHRGYSGSQASDSEGHSEDSDTQSVSAQG 2063
G + G G + + G + + EG E+ + + G
Sbjct: 885 GEGEEEGEGEGEEEEGEGEGEEEGEGEGEEEEGEGKGEEEGEEGEGEGEEEEGEGEGEDG 944
Query: 2064 KAGPHQQSHKESARGQSGESSG-RSGSFLYQVSTHE-QSESTHGQSAPSTGGRQGSHYDQ 2121
+ ++ + + GE G G + E + E G+ G +G +
Sbjct: 945 EGEGEEEEGEWEGEEEEGEGEGEEEGEGEGEEGEGEGEEEEGEGEGEEEEGEEEGEEEGE 1004
Query: 2122 AQDSSRHSASQEGQDTIRGHPGPSRGGRQGSHQE-----QSVDRSGHSGSHHSHTTSQGR 2176
++ +E + + G G +G +E + ++ G + + +
Sbjct: 1005 GEEEGEGEGEEEEEGEVEGEVEGEEGEGEGEEEEGEEEGEEREKEGEGEENRRNREEEEE 1064
Query: 2177 SDASRGQSGSRSASR---KTYDKEQSGDGSRHSGSH 2209
+ ++G R + Y K GS G H
Sbjct: 1065 EEGKYQETGEEENERQDGEEYKKVSKIKGSVKYGKH 1100
Score = 70.1 bits (170), Expect = 4e-11
Identities = 99/599 (16%), Positives = 179/599 (29%), Gaps = 96/599 (16%)
Query: 195 DNRKRLSERLEEKEDNE-EGVYDYENTGRMTQKWIQSGHIATYYTIQDEAYDTTDSLLEE 253
D + E E ED++ G+ + E + G + D+ D + + E
Sbjct: 581 DEEVEIPEEKEGAEDSKGNGIEEQEVEANEENVKVHGGRKEKTEILSDDLTDKAE--VSE 638
Query: 254 NKIYERSRSSDGKSSSQVNRSRHENTSQVPLQESRTRK--RRGSRVSQDRDSEGHSEDSE 311
K + DG ++ Q+ K + R +R EG E +E
Sbjct: 639 GKAKSVGEAEDGPEGRGDGTCEEGSSGAEHWQDEEREKGEKDKGRGEMERPGEGEKELAE 698
Query: 312 RHSGSASRNHHGSAWEQSRDGSRHPRSHDEDRASHGHSADSSRQSGTRHAETSSRGQTAS 371
+ W++ RDG + E GH + +++ E G+
Sbjct: 699 KEE-----------WKK-RDGEEQEQKEREQ----GHQKERNQEMEEGGEEEHGEGE--- 739
Query: 372 SHEQARSSPGERHGSGHQQSADSSRHSATGRGQASSAVSDRGHRGSSGSQASDSEGHSEN 431
E R E+ G G ++ G G+ V + + + G E
Sbjct: 740 EEEGDREEEEEKEGEGKEE----------GEGE---EVEGEREKEEGERKKEERAGKEEK 786
Query: 432 SDTQSVSGHGKAGLRQQSHQESTRGRSGERSGRSGSSLYQVSTHEQPDSAHGRTGTSTGG 491
+ + G G+ +E T GR E+ E+ G G
Sbjct: 787 GEEEGDQGEGE--------EEETEGRGEEK--------------EEGGEVEGGEVEEGKG 824
Query: 492 RQGSHHEQARDSSRHSASQEGQDTIRGHPGSSRGGRQGSHHEQSVNRSGHSGSHHSHTTS 551
+ E+ +E + G +G +G E G G
Sbjct: 825 EREEEEEEGEGEEEEGEGEEEEGEGEEEEGEGKGEEEGEEGEG--EEEGEEGE------G 876
Query: 552 QGRSDASHGQSGSRSASRQTRNEEQSGDGTRHSGSRHHEASSQADSSRHSQVGQGQSSGP 611
+G + G+ G + EE G+G E + + G+G+
Sbjct: 877 EGEEEEGEGE-GEEEGEGEGEEEEGEGEGEEEGEGEGEEEEGEGKGEEEGEEGEGEG--- 932
Query: 612 RTSRNQGSSVSQDSDSQGHSEDSERWSGSASRNHHGSAQEQSRDGSRHPRSHHEDRAGHG 671
+G +D + +G E+ E W G G +E+ E+ G G
Sbjct: 933 --EEEEGEGEGEDGEGEGEEEEGE-WEGEEEEG-EGEGEEEGEGEGEEGEGEGEEEEGEG 988
Query: 672 H-SADSSRKSGTRHTQNSSSGQAASSHEQARSSAGERHGSRHQLQSADSSRHSGTGHGQA 730
+ + G + G+ E+ GE G G G G+
Sbjct: 989 EGEEEEGEEEGEEEGEGEEEGEGEGEEEEEGEVEGEVEG------------EEGEGEGEE 1036
Query: 731 SSAVRDSGHRGSSGSQATDSEGHSEDSDTQSVSGHGQAGHHQQSHQESARDRSGERSRR 789
G + + EG E++ + G +Q++ +E + GE ++
Sbjct: 1037 --------EEGEEEGEEREKEGEGEENRRNREEEEEEEGKYQETGEEENERQDGEEYKK 1087
Score = 70.1 bits (170), Expect = 4e-11
Identities = 91/556 (16%), Positives = 172/556 (30%), Gaps = 41/556 (7%)
Query: 1065 GSSGSQASDSEGHSEESDTQSVSGHGQDGPHQQSHQESARDWSGGRSGRSGSFIYQVSTH 1124
G+ S+ + E E++ ++V HG + + D + G++ S V
Sbjct: 592 GAEDSKGNGIEEQEVEANEENVKVHGGRKEKTEILSDDLTDKAEVSEGKAKS----VGEA 647
Query: 1125 EQSESAHGRTRTSTGRRQGSHHEQA------RDSSRHSASQEGQDTIRAHPGSRRGGRQG 1178
E G G H + +D R + G+ R G
Sbjct: 648 EDGPEGRGDGTCEEGSSGAEHWQDEEREKGEKDKGRGEMERPGEGEKELAEKEEWKKRDG 707
Query: 1179 SHHEQSVDRSGHSGSHHSHTTSQGRSDASHGQSGSRSASRQTRKD---KQSGDGSRHSGS 1235
EQ GH + G + G+ + K+ K+ G+G G
Sbjct: 708 EEQEQKEREQGHQKERNQEMEEGGEEEHGEGEEEEGDREEEEEKEGEGKEEGEGEEVEGE 767
Query: 1236 RHHEAASWADSSRHSQVGQEQSSGSRTSRHQGSSVSQDSDSERHSDDSERLSGSASRNHH 1295
R E + + + G+E+ + +G + E + E + G
Sbjct: 768 REKEE---GERKKEERAGKEEKGEEEGDQGEGEEEETEGRGEEKEEGGE-VEGGEVEEGK 823
Query: 1296 GSSREQSRDGSRHPGFHQEDRASHGHSADSSRQSGTHHTESSSHGQAVSSHEQARSSPGE 1355
G E+ +G E+ G + + E G+ E+ GE
Sbjct: 824 GEREEEEEEG------EGEEEEGEGEEEEGEGE------EEEGEGK---GEEEGEEGEGE 868
Query: 1356 RHGSRHQQSADSSRHSGIGHRQASSAVRDSGHRGSSGSQVTNSEGHSEDSDTQSVSAHGQ 1415
G + + G G + + G G + EG E+ + + G+
Sbjct: 869 EEGEEGEGEGEEEEGEGEGEEEGEGEGEEEEGEG-EGEEEGEGEGEEEEGEGKG-EEEGE 926
Query: 1416 AGPHQQSHKE-SARGQSGESSGRSRSFLYQVSSHEQSE---STHGQTAPSTGGRQGSRHE 1471
G + +E G+ GE G ++ E+ E G+ G +G E
Sbjct: 927 EGEGEGEEEEGEGEGEDGEGEGEEEEGEWE-GEEEEGEGEGEEEGEGEGEEGEGEGEEEE 985
Query: 1472 QARNSSRHSASQDGQDTIRGHPGSSRGGRQGSYHEQSVDRSGHSGYHHSHTTPQGRSDAS 1531
++G++ G G + E + G G
Sbjct: 986 GEGEGEEEEGEEEGEEEGEGEEEGEGEGEEEEEGEVEGEVEGEEGEGEGEEEEGEEEGEE 1045
Query: 1532 HGQSGPRSASRQTRNEEQSGDGS-RHSGSRHHEPSTRAGSSRHSQV-GQGESAGSKTSRR 1589
+ G +R+ R EE+ +G + +G +E + S++ G + KT ++
Sbjct: 1046 REKEGEGEENRRNREEEEEEEGKYQETGEEENERQDGEEYKKVSKIKGSVKYGKHKTYQK 1105
Query: 1590 QGSSVSQDRDSEGHSE 1605
+ + +Q E S+
Sbjct: 1106 KSVTNTQGNGKEQRSK 1121
Score = 69.3 bits (168), Expect = 7e-11
Identities = 74/458 (16%), Positives = 136/458 (29%), Gaps = 41/458 (8%)
Query: 2822 QGRSDASRGQSGSRSASRTTRNEEQSGDGSRHSGSRHHEASTHADISRHSQAVQGQSEGS 2881
+GR D + + GS A E + G+ + G ++ R + + +E
Sbjct: 652 EGRGDGTC-EEGSSGAEHWQDEEREKGEKDKGRG----------EMERPGEGEKELAEKE 700
Query: 2882 RRSRRQGSSVSQDSDSEGHSEDSERWSGSASRNHHGSAQEQLRDGSRHPRSHQEDRAGHG 2941
+R G Q +GH ++ + HG +E+ D R +E++ G G
Sbjct: 701 EWKKRDGEEQEQKEREQGHQKERNQEMEEGGEEEHGEGEEEEGD-----REEEEEKEGEG 755
Query: 2942 -HSADSSRQSGTRHTQTSSGGQAASSHEQARSSAGERHGSHHQQSADSSRHSGIGHGQAS 3000
+ G R + G+ + GE G + + + G +
Sbjct: 756 KEEGEGEEVEGEREKEE---GERKKEERAGKEEKGEEEGDQGEGEEEETEGRGEEKEEGG 812
Query: 3001 SAVRDSGHRGYSGSQASDNEGHSEDSDTQSVSAHGQAGSHQQSH---QESARGRSGETSG 3057
G + + EG E+ + + G+ G ++ +E GE G
Sbjct: 813 EVEGGEVEEGKGEREEEEEEGEGEEEEGEGEEEEGE-GEEEEGEGKGEEEGEEGEGEEEG 871
Query: 3058 HSGSFLYQVSTHEQSESSHGWTGPSTRGRQGSRHEQAQDSSRHSASQYGQDTIRGHPGSS 3117
G + E G +G E+ + + G+ G G
Sbjct: 872 EEGEGEGEEEEGEGEGEEEGEGEGEEEEGEGEGEEEGEGEGEEEEGE-GKGEEEGEEGEG 930
Query: 3118 RGGR----------QGYHHEHSVDSSGHSGSHHSHTTSQGRSDASRGQSGSRSASRTTRN 3167
G +G E + G +G + G+
Sbjct: 931 EGEEEEGEGEGEDGEGEGEEEEGEWEGEEEEGEGEGEEEGEGEGEEGEGEGEEEEGEGEG 990
Query: 3168 EEQSGDSSRHSVSRHHEASTHADISRHSQAVQGQSEGSRRSRRQGSSVSQDSDSEGHSED 3227
EE+ G+ E V+G+ EG +G ++ + E E+
Sbjct: 991 EEEEGEEEGEEEGEGEEEGEGEGEEEEEGEVEGEVEG-----EEGEGEGEEEEGEEEGEE 1045
Query: 3228 SERWSGSASRNHRGSVQEQSRHGSRHPRSHHEDRAGHG 3265
E+ G N R +E+ G E+ G
Sbjct: 1046 REK-EGEGEENRRNREEEEEEEGKYQETGEEENERQDG 1082
Score = 68.6 bits (166), Expect = 1e-10
Identities = 89/564 (15%), Positives = 175/564 (31%), Gaps = 50/564 (8%)
Query: 2659 QQSADSSRHSGIGHGQASSAVRDSGHRGYSGSQASDNEGHSEDSDTQSVSAHGQAGSHQQ 2718
++ A+ S+ +GI + + + + G + E S+D ++ + G+A S +
Sbjct: 590 KEGAEDSKGNGIEEQEVEA---NEENVKVHGGRKEKTEILSDDLTDKAEVSEGKAKSVGE 646
Query: 2719 SHQESARGRSGET--SGHSGSFLYQVSTHEQSESSHGWTGPSTRGRQGSRH--EQAQDSS 2774
+ ++ GR T G SG+ +Q E+ E G G R +G + E+ +
Sbjct: 647 A-EDGPEGRGDGTCEEGSSGAEHWQDEEREKGEKDKG-RGEMERPGEGEKELAEKEEWKK 704
Query: 2775 RHSASQDGQDTIRGHPGS-SRGGRQGYHHEHSVDSSGHSGSHHSHTTSQGRSDASRGQSG 2833
R Q+ ++ +GH ++ +G EH G + + G+
Sbjct: 705 RDGEEQEQKEREQGHQKERNQEMEEGGEEEH--------GEGEEEEGDREEEEEKEGEGK 756
Query: 2834 SRSASRTTRNEEQSGDGSRHSGSRHHEASTHADISRHSQAVQGQSEGSRRSRRQGSSVSQ 2893
E + +G R R + + + + ++EG + +G V
Sbjct: 757 EEGEGEEVEGEREKEEGERKKEERAGKEEKGEEEGDQGEGEEEETEGRGEEKEEGGEVEG 816
Query: 2894 DSDSEGHSEDSERWSGSASRNHHGSAQEQLRDGSRHPRSHQEDRAGHGHSADSSRQSGTR 2953
EG E E G +E+ +G + + G + + G
Sbjct: 817 GEVEEGKGEREEEEEEGEGEEEEGEGEEEEGEGEEEEGEGKGEEEGEEGEGEEEGEEGEG 876
Query: 2954 HTQTSSGGQAASSHEQARSSAGERHGSHHQQ-SADSSRHSGIGHGQASSAVRDSGHRGYS 3012
+ G + E G ++ + G G G+ + G G
Sbjct: 877 EGEEEEGEGEGEEEGEGEGEEEEGEGEGEEEGEGEGEEEEGEGKGE------EEGEEGEG 930
Query: 3013 GSQASDNEGHSEDSDTQSVSAHGQAGSHQQSHQESARGRSGETSGHSGSFLYQVSTHEQS 3072
+ + EG ED + + G+ + +E G GE G +
Sbjct: 931 EGEEEEGEGEGEDGEGEGEEEEGE----WEGEEEEGEG-EGEEEGEG-----------EG 974
Query: 3073 ESSHGWTGPSTRGRQGSRHEQAQDSSRHSASQYGQDTIRGHPGSSRGGRQGYHHEHSVDS 3132
E G +G E + + G++ G G + E +
Sbjct: 975 EEGEG---------EGEEEEGEGEGEEEEGEEEGEEEGEGEEEGEGEGEEEEEGEVEGEV 1025
Query: 3133 SGHSGSHHSHTTSQGRSDASRGQSGSRSASRTTRNEEQSGDSSRHSVSRHHEASTHADIS 3192
G G R + G +R R EE+ + +
Sbjct: 1026 EGEEGEGEGEEEEGEEEGEEREKEGEGEENRRNREEEEEEEGKYQETGEEENERQDGEEY 1085
Query: 3193 RHSQAVQGQSEGSRRSRRQGSSVS 3216
+ ++G + + Q SV+
Sbjct: 1086 KKVSKIKGSVKYGKHKTYQKKSVT 1109
Score = 67.4 bits (163), Expect = 3e-10
Identities = 77/465 (16%), Positives = 146/465 (31%), Gaps = 38/465 (8%)
Query: 112 DNKQEENKENRKRPSSLERRNNRKGNKGRSKSPRETGGKRHESSSEK-KERKGYSPTHRE 170
D EE + ER K +KGR + R G++ + E+ K+R G +E
Sbjct: 656 DGTCEEGSSGAEHWQDEEREKGEK-DKGRGEMERPGEGEKELAEKEEWKKRDGEEQEQKE 714
Query: 171 EEYGKNHHNSSKKEKNKTENTRLGDNRKRLSERLEEKEDNEEGVYDYENTGRMTQKWIQS 230
E G + + E+ E G+ E ++E+ EE + + G +
Sbjct: 715 REQGHQKERNQEMEEGGEEEHGEGE------EEEGDREEEEEKEGEGKEEG-------EG 761
Query: 231 GHIATYYTIQDEAYDTTDSLLEENKIYERSRSSDGKSSSQVNRSRHENTSQVPLQESRTR 290
+ ++ + +E K E +G+ R E ++
Sbjct: 762 EEVEGEREKEEGERKKEERAGKEEKGEEEGDQGEGEEEETEGRG-EEKEEGGEVEGGEVE 820
Query: 291 KRRGSRVSQDRDSEGHSEDSERHSGSASRNHHGSAWEQSRDGSRHPRSHDEDRASHGHSA 350
+ +G R ++ + EG E+ E G E+ +G + + G
Sbjct: 821 EGKGEREEEEEEGEGEEEEGE------GEEEEGEGEEEEGEGKGEEEGEEGEGEEEGEEG 874
Query: 351 DSSRQSGTRHAETSSRGQTASSHEQARSSPGERHGSGHQQSADSSRHSATGRGQASSAVS 410
+ + E G+ E+ GE G G + G+G+
Sbjct: 875 EGEGEEEEGEGEGEEEGEGEGEEEEGEGE-GEEEGEG-----EGEEEEGEGKGE------ 922
Query: 411 DRGHRGSSGSQASDSEGHSENSDTQSVSGHGKAGLRQQSHQESTRGRSGERSGRSGSSLY 470
+ G G + + EG E+ + + G+ ++ E GE G G
Sbjct: 923 EEGEEGEGEGEEEEGEGEGEDGEGEGEEEEGE-WEGEEEEGEGEGEEEGEGEGEEGEG-- 979
Query: 471 QVSTHEQPDSAHGRTGTSTGGRQGSHHEQARDSSRHSASQEGQDTIRGHPGSSRG-GRQG 529
+ E G G +G E+ E + + G G G +G
Sbjct: 980 EGEEEEGEGEGEEEEGEEEGEEEGEGEEEGEGEGEEEEEGEVEGEVEGEEGEGEGEEEEG 1039
Query: 530 SHHEQSVNRSGHSGSHHSHTTSQGRSDASHGQSGSRSASRQTRNE 574
+ + G + + + + + ++G RQ E
Sbjct: 1040 EEEGEEREKEGEGEENRRNREEEEEEEGKYQETGEEENERQDGEE 1084
Score = 65.1 bits (157), Expect = 1e-09
Identities = 108/649 (16%), Positives = 199/649 (30%), Gaps = 69/649 (10%)
Query: 2887 QGSSVSQDSDSEGHSEDSERWSGSASRNH--HGSAQEQLRDGSRHPRSHQEDRAGHGHSA 2944
Q ++++++ DS+ + E SE G A + H G Q + + A
Sbjct: 534 QDTALTENDDSDEYEEMSEMKEGKACKQHVSQGIFMTQPATTIEAFSDEEVEIPEEKEGA 593
Query: 2945 DSSRQSGTRHTQTSSGGQAASSHEQARSSAGERHGSHHQQSADSSRHSGIGHGQASSAVR 3004
+ S+ +G + + + H R E A+ S G+A
Sbjct: 594 EDSKGNGIEEQEVEANEENVKVHG-GRKEKTEILSDDLTDKAEVSEGKAKSVGEAEDGPE 652
Query: 3005 DSG----HRGYSGS---QASDNEGHSEDSDTQSVSAHGQAGSHQQSHQESARGRSGETS- 3056
G G SG+ Q + E +D + G+ G + + +E + R GE
Sbjct: 653 GRGDGTCEEGSSGAEHWQDEEREKGEKDKGRGEMERPGE-GEKELAEKEEWKKRDGEEQE 711
Query: 3057 ------GHSGSFLYQVSTHEQSESSHGWTGPSTRGRQGSRHEQAQDSSRHSASQYGQDTI 3110
GH ++ E E HG +G R E+ + G++ +
Sbjct: 712 QKEREQGHQKERNQEME--EGGEEEHG----EGEEEEGDREEEEEKEGEGKEEGEGEE-V 764
Query: 3111 RGHPGSSRGGRQGYHH---EHSVDSSGHSGSHHSHTTSQGRSDASRG---QSGSRSASRT 3164
G G R+ E + G G T + G + G +
Sbjct: 765 EGEREKEEGERKKEERAGKEEKGEEEGDQGEGEEEETEGRGEEKEEGGEVEGGEVEEGKG 824
Query: 3165 TRNEEQSGDSSRHSVSRHHEASTHADISRHSQAVQGQSEGSRRSRR-QGSSVSQDSDSEG 3223
R EE+ E + +G+ +G +G ++ + EG
Sbjct: 825 EREEEEEEGEGEEEEGEGEEEEGEGEEE------EGEGKGEEEGEEGEGEEEGEEGEGEG 878
Query: 3224 HSEDSERWSGSASRNHRGSVQEQSRHGSRHPRSHHEDRAGHGHSADRSRQSGTRHAETSS 3283
E+ E G G +E G E+ G G + + E
Sbjct: 879 EEEEGEG-EGEEEGEGEGEEEEGEGEGEEEGEGEGEEEEGEGKGEEEGEEGEGEGEEEEG 937
Query: 3284 GGQAASSHEQARSSPGERHGSRHQQSADSSRHSGIPRGQASSAVRDSRHWGSSGSQASDS 3343
G+ + GE G + + + + G + +
Sbjct: 938 EGEGEDGEGEGEEEEGEWEGEEEEGEGEGEEEGEGEGEEGEGEGEEEEGEGEGEEEEGEE 997
Query: 3344 EGHSEESDTQSVSGHGQAGPHQQSHQESARDRSGGRSGRSGSFLYQVSTHEQSESAHGRT 3403
EG E G G+ ++ E + G +V + E G
Sbjct: 998 EGEEE--------GEGE----EEGEGEGEEEEEG-----------EVEGEVEGEEGEGEG 1034
Query: 3404 RTSTGRRQGSHHEQARDSSRHSASQEGQDTIRG---HPGSSRRGRQGSHYEQSVDRSGHS 3460
G +G E+ + + ++E ++ G G RQ + V + S
Sbjct: 1035 EEEEGEEEGEEREKEGEGEENRRNREEEEEEEGKYQETGEEENERQDGEEYKKVSKIKGS 1094
Query: 3461 GSHHSHTTSQGRSDASRGQSGSRSASR---QTRNDEQSG-DGSRHSWSH 3505
+ H T Q +S + +G S+ Q++ ++G GS+ W++
Sbjct: 1095 VKYGKHKTYQKKSVTNTQGNGKEQRSKMPVQSKRLLKNGPSGSKKFWNN 1143
Score = 63.9 bits (154), Expect = 3e-09
Identities = 95/568 (16%), Positives = 173/568 (30%), Gaps = 75/568 (13%)
Query: 91 KENLPISGHKHRKHSHHDKHEDNKQEENKENRKRPSSLERRNNRKGNKGRSKSPRETGGK 150
+EN+ + G + K +K E ++ K E G +GR E G
Sbjct: 610 EENVKVHGGRKEKTEILSDDLTDKAEVSEGKAKSVGEAE-----DGPEGRGDGTCEEGSS 664
Query: 151 RHESSSEKKERKGYSPTHREE--EYGKNHHNSSKKEKNKTENTRLGDNRKRLSERLEEKE 208
E +++ KG R E G+ ++KE+ K + + ++R E+ +KE
Sbjct: 665 GAEHWQDEEREKGEKDKGRGEMERPGEGEKELAEKEEWKKRDGEEQEQKER--EQGHQKE 722
Query: 209 DNEEGVYDYENTGRMTQKWIQSGHIATYYTIQDEAYDTTDSLLEENKIYERSRSSDGKSS 268
N+E ++ G + ++E D + EE K E +G+
Sbjct: 723 RNQE---------------MEEGGEEEHGEGEEEEGDREE---EEEKEGEGKEEGEGEE- 763
Query: 269 SQVNRSRHENTSQVPLQESRTRKRRGSRVSQDRDSEGHSEDSERHSGSASRNHHGSAWEQ 328
E K G R ++R + + E G E+
Sbjct: 764 ----------------VEGEREKEEGERKKEERAGKEEKGEEEGDQGEGEEEETEGRGEE 807
Query: 329 SRDGSRHPRSHDEDRASHGHSADSSRQSGTRHAETSSRGQTASSHEQARSSPGERHGSGH 388
+G E+ G + + E + E+ GE G
Sbjct: 808 KEEGGEVEGGEVEE--GKGEREEEEEEGEGEEEEGEGEEEEGEGEEEEGEGKGEEEG--- 862
Query: 389 QQSADSSRHSATGRGQASSAVSDRGHRGSSGSQASDSEGHSENSDTQSVSGHGKAGLRQQ 448
+ + G G+ + G + + EG E + G G+ +
Sbjct: 863 -EEGEGEEEGEEGEGEGEEEEGE-----GEGEEEGEGEGEEEEGE-----GEGEEEGEGE 911
Query: 449 SHQESTRGRSGERSGRSGSSLYQVSTHEQPDSAHGRTGTSTGGRQGSHHEQARDSSRHSA 508
+E G+ GE G G E+ G G G + E +
Sbjct: 912 GEEEEGEGK-GEEEGEEGEG----EGEEEEGEGEGEDGEGEGEEEEGEWEGEEEEGEGEG 966
Query: 509 SQEGQDTIRGHPGSSRGGRQGSHHEQSVNRSGHSGSHHSHTTSQGRSDASHGQSGSRSAS 568
+EG+ G G G + E G +G + + G
Sbjct: 967 EEEGEG--EGEEGEGEGEEEEGEGEGEEEEGEEEGEEEGEGEEEGEGEGEEEEEG--EVE 1022
Query: 569 RQTRNEEQSGDGTRHSG---SRHHEASSQADSSRHSQVGQGQSSGPRTSRNQGSSVSQDS 625
+ EE G+G G E + + +R ++ + + G + + QD
Sbjct: 1023 GEVEGEEGEGEGEEEEGEEEGEEREKEGEGEENRRNREEEEEEEGKYQETGEEENERQDG 1082
Query: 626 DSQGHSEDSERWSGSASRNHHGSAQEQS 653
+ + + GS H + Q++S
Sbjct: 1083 EEY---KKVSKIKGSVKYGKHKTYQKKS 1107
Score = 58.9 bits (141), Expect = 1e-07
Identities = 76/460 (16%), Positives = 138/460 (30%), Gaps = 31/460 (6%)
Query: 3550 EDSERWSGSASRNHRGSAQEQS---RDGSRHPTSHHEDRAGHGHSAESSRQSGTHHAENS 3606
E +E G+ A E++ G + T D + AE+
Sbjct: 591 EGAEDSKGNGIEEQEVEANEENVKVHGGRKEKTEILSDDLTDKAEVSEGKAKSVGEAEDG 650
Query: 3607 SGGQAASSHEQARSSAGERHGSHHQQSADSSRHSGI----GHGQASSAVRDSGHR--GSS 3660
G+ + E+ SS E ++ + + G G G+ A ++ + G
Sbjct: 651 PEGRGDGTCEEG-SSGAEHWQDEEREKGEKDKGRGEMERPGEGEKELAEKEEWKKRDGEE 709
Query: 3661 GSQASDSEGHSEDSDTQSVSA----HGQAGPHQQSHQESTRGRSAGRSGRSGSFLYQVST 3716
Q +GH ++ + + HG+ + +E G+ G +
Sbjct: 710 QEQKEREQGHQKERNQEMEEGGEEEHGEGEEEEGDREEEEEKEGEGKEEGEGEEVEGERE 769
Query: 3717 HEQSE-SAHGRAGPSTGGRQGSRH---EQARDSSRHSASQEGQDTIRGHPGSRRGGRQGS 3772
E+ E RAG G + E+ R +EG + G +G R+
Sbjct: 770 KEEGERKKEERAGKEEKGEEEGDQGEGEEEETEGRGEEKEEGGEVEGGEVEEGKGEREEE 829
Query: 3773 YHEQSVDRSGHSGSHHSHTTSQGRSDASHGQSGSRSASRETRNEEQSGDGSRHSGSRHHE 3832
E + G + + G+ E EE G+G G E
Sbjct: 830 EEEGEGEEEEGEGEEEEGEGEEEEGEGK-GEEEGEEGEGEEEGEEGEGEGEEEEGEGEGE 888
Query: 3833 ASTQADSSRHSQSGQGESAG---SRRSRRQGSSVSQDSDSEAYPEDSERRSESASRNHHG 3889
+ + G+GE G +G + + E E+ E E G
Sbjct: 889 EEGEGEGEEEEGEGEGEEEGEGEGEEEEGEGKGEEEGEEGEGEGEEEEGEGEGEDGEGEG 948
Query: 3890 SSREQSRDGSRHPGSSHRDTASHVQSSPVQSDSSTAKEHGHFSSLSQDSAYHSGIQSRGS 3949
E +G G + + + + +E G ++ + G
Sbjct: 949 EEEEGEWEGEEEEGEGEGEEEGEGEGE--EGEGEGEEEEGEGEGEEEEG------EEEGE 1000
Query: 3950 PHSSSSYHYQSEGTERQKGQ-SGLVWRHGSYGSADYDYGE 3988
+ EG E ++G+ G V G + + GE
Sbjct: 1001 EEGEGEEEGEGEGEEEEEGEVEGEVEGEEGEGEGEEEEGE 1040
Score = 53.5 bits (127), Expect = 4e-06
Identities = 60/382 (15%), Positives = 118/382 (30%), Gaps = 29/382 (7%)
Query: 92 ENLPISGHKHRKHSHHDKHEDNKQEENKENRKRPSSLERRNNRKGNKGRSKSPRETGGKR 151
E + G + ++ K E +EE E E + + + GG+
Sbjct: 760 EGEEVEGEREKEEGERKKEERAGKEEKGEEEGDQGEGEEEETEGRGEEKEEGGEVEGGEV 819
Query: 152 HESSSEKKERKGYSPTHREEEYGKNHHNSSKKEKNKTENTRLGDNRKRLSE------RLE 205
E E++E + EE G+ ++E+ + + G+ + E E
Sbjct: 820 EEGKGEREEEEEEGEGEEEEGEGEEEEGEGEEEEGEGKGEEEGEEGEGEEEGEEGEGEGE 879
Query: 206 EKEDNEEGVYDYENTGRMTQKWIQSGHIATYYTIQDEAYDTTDSLLEENKIYERSRSSDG 265
E+E EG + E G + + ++E + E K E +G
Sbjct: 880 EEEGEGEGEEEGEGEGEEEEGEGEG---------EEEGEGEGEEEEGEGKGEEEGEEGEG 930
Query: 266 KSSSQVNRSRHENTSQVPLQESRTRKRRGSRVSQDRDSEGHSEDSERHSGSASRNHHGSA 325
+ + E+ E + G ++ + EG E+ G G
Sbjct: 931 EGEEEEGEGEGED------GEGEGEEEEGEWEGEEEEGEGEGEEEGEGEGEEG---EGEG 981
Query: 326 WEQSRDGSRHPRSHDEDRASHGHSADSSRQSGTRHAETSSRGQTASSHEQARSSPGERHG 385
E+ +G +E+ G + G E G+ E+ E G
Sbjct: 982 EEEEGEGEGEEEEGEEEGEEEGEGEEEGEGEGEEEEEGEVEGEVEG--EEGEGEGEEEEG 1039
Query: 386 SGHQQSADSSRHSATGRGQASSAVSDRGHRGSSGSQASDSEGHSENSDTQSVSG---HGK 442
+ + R + G +G + ++ + E + G +GK
Sbjct: 1040 EEEGEEREKEGEGEENRRNREEEEEEEGKYQETGEEENERQDGEEYKKVSKIKGSVKYGK 1099
Query: 443 AGLRQQSHQESTRGRSGERSGR 464
Q+ +T+G E+ +
Sbjct: 1100 HKTYQKKSVTNTQGNGKEQRSK 1121
Score = 37.4 bits (85), Expect = 0.31
Identities = 26/103 (25%), Positives = 42/103 (40%), Gaps = 2/103 (1%)
Query: 87 ESTRKENLPISGHKHRKHSHHDKHEDNKQEENKENRKRPSSLERRNNRKGNKGRSKSPRE 146
E +E + G + + E+ +EE +E K E R NR+ + +E
Sbjct: 1012 EGEEEEEGEVEGEVEGEEGEGEGEEEEGEEEGEEREKEGEGEENRRNREEEEEEEGKYQE 1071
Query: 147 TGGKRHESSSEKKERKGYSPTHREEEYGKNHHNSSKKEKNKTE 189
TG + +E + +E K S +YGK H KK T+
Sbjct: 1072 TGEEENE-RQDGEEYKKVSKIKGSVKYGK-HKTYQKKSVTNTQ 1112
>gi|158854042 hypothetical protein LOC222183 [Homo sapiens]
Length = 653
Score = 87.0 bits (214), Expect = 3e-16
Identities = 143/604 (23%), Positives = 216/604 (35%), Gaps = 79/604 (13%)
Query: 157 EKKERKGYSPTHREEEYGKNHHNSSKKEKNKTENTRLGDNRKRLSERLEEKE-------- 208
E E +GYS ++ G +KE T R G + + RL E
Sbjct: 72 EMMEEQGYSEEEIRQKVGTFRQMLMEKEGVLTREDRPGGHIVAETPRLTEGAEPGLEYAP 131
Query: 209 -DNEEGVYDYE--------NTGRMTQKWIQS--------------GHIATYYTIQDEAYD 245
D+++G D + + G T+ W S GH + + E+
Sbjct: 132 FDDDDGPVDCDCPASCYRGHRGYRTKHWSSSSASPPPKKKKKKKGGHRRSRKKRRLESEC 191
Query: 246 TTDS---LLEENKIYERSRSSDGKSSSQVNRSRHENTSQVPLQESRTRKRRGSRVSQDRD 302
+ S L ++ K ++ R S S+ R +S+ +E K+R S R
Sbjct: 192 SCGSSSPLRKKKKSVKKHRRDRSDSGSRRKRRHRSRSSKCKRKEKNKEKKRPHTESPGRR 251
Query: 303 SEGHSEDSERHSGSASRNHHGSAWEQSRDGSR-HPRSHDEDRASHGHSADSSRQSGTRHA 361
S HS S HS S S S + SR SR P+ DE R + + SR
Sbjct: 252 SHRHSSGSS-HSPSLS-----SHYSDSRSPSRLSPKHRDEGRKTGSQRSSGSRSPSPSGG 305
Query: 362 ETSSRGQTASSHEQARSSPGERHGSGHQQSADSSRHSATGRGQASSAVSDRGHRGSSGSQ 421
Q Q + G R GS H S S R +A++A RG +
Sbjct: 306 SGWGSPQRNGGSGQRSGAHGGRPGSAHSPPDKPSSPSPRVRDKAAAAAPTPPARG----K 361
Query: 422 ASDSEGHSENSDTQSVSGHGKAGLRQQSHQESTRGRSG----ERSGR--------SGSSL 469
S S + +S + G AG R++ + R RS R GR GSS
Sbjct: 362 ESPSPRSAPSSQGRGGRAAGGAGRRRRRRRRRRRSRSSASAPRRRGRRRPRPAPPRGSSR 421
Query: 470 YQVSTHEQPDSAHGRTGTSTGGRQGSHHEQARDSSRHSASQEGQDTIRGHPGSSRGGRQG 529
DS GR G GS R P GR+G
Sbjct: 422 SLSRARSSSDSGSGRGAPGPGPEPGSERGHGGHGKRAKERPPRARPASTSPSPGAHGRRG 481
Query: 530 SHHEQSVNRSGHS-----GSHHSHTTSQGRSDASHGQSGSRSAS-RQTRNEEQSGDGTRH 583
+S +RS S S + S+ RS S SRS S ++ + ++ G+G
Sbjct: 482 GPEGKSSSRSPGPHPRSWSSSRSPSKSRSRSAEKRPHSPSRSPSPKKPLSRDKDGEGR-- 539
Query: 584 SGSRHHEASSQADSSRHSQVGQGQSSGPRTSRNQGSSVSQDSDSQGHSEDSERWSGSASR 643
+RH S+A+++R + + S + R+ S + + + S S
Sbjct: 540 --ARH----SEAEATRARRRSRSYSPIRKRRRDSPSFMEPRRITSARKRPIPYYRPSPSS 593
Query: 644 NHHG-SAQEQSRDGSRHPRSHHEDRAGHGHSADSSRKSGTR-HTQNSSSGQAASSHEQAR 701
+ S+ +R SR P GH H + SSR GTR T++ S + S H ++
Sbjct: 594 SSSCLSSDYSTRSHSRSP------SPGHSHGSYSSRSHGTRSRTRSPSRTPSPSYHSRSS 647
Query: 702 SSAG 705
S +G
Sbjct: 648 SESG 651
Score = 83.2 bits (204), Expect = 5e-15
Identities = 127/518 (24%), Positives = 185/518 (35%), Gaps = 52/518 (10%)
Query: 3458 GHSGSHHSHTTSQGRSDASRGQSGSRSASRQTRNDEQ-SGDGSRHSWSHHHEASTQADSS 3516
GH G H +S S + + + R++R + + S S S +
Sbjct: 150 GHRGYRTKHWSSSSASPPPKKKKKKKGGHRRSRKKRRLESECSCGSSSPLRKKKKSVKKH 209
Query: 3517 RHSQSGQGQSAGPRTSRNQGSSVSQDSDSQGHSEDSERWSGSASR-NHRGSAQEQSRDGS 3575
R +S +G R R S S+ + + E + S R +HR S+ GS
Sbjct: 210 RRDRS----DSGSRRKRRHRSRSSKCKRKEKNKEKKRPHTESPGRRSHRHSS------GS 259
Query: 3576 RHP---TSHHEDRAGHGHSAESSRQSGTHHAENSSGGQAASSHEQARSSAGERHGSHHQQ 3632
H +SH+ D S SR S H E G SS ++ S +G Q+
Sbjct: 260 SHSPSLSSHYSD------SRSPSRLSPKHRDEGRKTGSQRSSGSRSPSPSGGSGWGSPQR 313
Query: 3633 SADSSRHSGIGHGQASSAVRDSGHRGSSGSQASDSEGHSEDSDTQSVSAHGQAGPHQQSH 3692
+ S + SG G+ SA S + D + + T P
Sbjct: 314 NGGSGQRSGAHGGRPGSAHSPPDKPSSPSPRVRDKAAAA--APTPPARGKESPSPRSAPS 371
Query: 3693 QESTRGRSAGRSGRSGSFLYQVSTHEQSESA---HGRAGPSTGGRQGSRHEQARD-SSRH 3748
+ GR+AG +GR + S SA GR P +GS +R SS
Sbjct: 372 SQGRGGRAAGGAGRRRRRRRRRRRSRSSASAPRRRGRRRPRPAPPRGSSRSLSRARSSSD 431
Query: 3749 SASQEGQDTIRGHPGSRRG-GRQGSYHEQSVDRSGHSGSHHSHTTSQGRSDASHGQSGSR 3807
S S G PGS RG G G ++ R+ + + S + GR G+S SR
Sbjct: 432 SGSGRGAPGPGPEPGSERGHGGHGKRAKERPPRARPASTSPS-PGAHGRRGGPEGKSSSR 490
Query: 3808 SASRETRNEEQSGDGSRHSGSRHHEASTQADSSRHSQSGQGESAGSRRSRRQGSSVSQDS 3867
S R+ S S+ S A+ HS S RS +S+D
Sbjct: 491 SPGPHPRSWSSSRSPSK-------SRSRSAEKRPHSPS---------RSPSPKKPLSRDK 534
Query: 3868 DSEAYPEDSERRSESASRNHHGSS--REQSRDGSRHPGSSHRDTASHVQSSPVQSDSSTA 3925
D E SE + A R S R++ RD R T++ + P S ++
Sbjct: 535 DGEGRARHSEAEATRARRRSRSYSPIRKRRRDSPSFM-EPRRITSARKRPIPYYRPSPSS 593
Query: 3926 KEHGHFSSLSQDSAYHSGIQSRGSPHSSSSYHYQSEGT 3963
S LS D + S +S HS SY +S GT
Sbjct: 594 SS----SCLSSDYSTRSHSRSPSPGHSHGSYSSRSHGT 627
Score = 82.8 bits (203), Expect = 6e-15
Identities = 124/530 (23%), Positives = 186/530 (35%), Gaps = 57/530 (10%)
Query: 412 RGHRGSSGSQASDSEGHSENSDTQSVSGHGKAGLRQQSHQESTRGRSGERSGRSGSSLYQ 471
RGHRG S S + G H+ S + R E GSS
Sbjct: 149 RGHRGYRTKHWSSSSASPPPKKKKKKKG---------GHRRSRKKRRLESECSCGSSS-P 198
Query: 472 VSTHEQPDSAHGRTGTSTGGRQGSHHEQARDSSRHSASQEGQDTIRGHPGSSRGGRQGSH 531
+ ++ H R + +G R+ H SS+ ++ ++ R H S GR+
Sbjct: 199 LRKKKKSVKKHRRDRSDSGSRRKRRHRSR--SSKCKRKEKNKEKKRPHTESP--GRRSHR 254
Query: 532 HEQSVNRSGHSGSHHSHTTSQGRSDASHGQSGSRSASRQTRNEEQS--------GDGTRH 583
H + S SH+S + S R H G ++ S+++ G R+
Sbjct: 255 HSSGSSHSPSLSSHYSDSRSPSRLSPKHRDEGRKTGSQRSSGSRSPSPSGGSGWGSPQRN 314
Query: 584 SGS-RHHEASSQADSSRHSQVGQGQSSGPRTSRNQGSSVSQDSDSQGHSEDSERWSGSAS 642
GS + A S HS + S PR R++ ++ + ++G S R S +S
Sbjct: 315 GGSGQRSGAHGGRPGSAHSPPDKPSSPSPRV-RDKAAAAAPTPPARGKESPSPR-SAPSS 372
Query: 643 RNHHGSAQEQSRDGSRHPRSHHEDRAGHGHSADSSRKSGTRHTQNSSSGQAASSHEQARS 702
+ G A + R R R+ SA + R+ G R + + ++ S +ARS
Sbjct: 373 QGRGGRAAGGAGRRRRRRRRRRRSRS----SASAPRRRGRRRPRPAPPRGSSRSLSRARS 428
Query: 703 SAGERHGSRHQLQSADSSRHSGTGHGQASSAVRDSGHRGSSGSQATDSEGHSEDSDTQSV 762
S+ GS S GHG ++ R S + H +
Sbjct: 429 SSDS--GSGRGAPGPGPEPGSERGHGGHGKRAKERPPRARPASTSPSPGAHGRRGGPEGK 486
Query: 763 SGHGQAGHHQQSHQES-----ARDRSGER----SRRSGSFLYQVSTHKQSE--SSHGWTG 811
S G H +S S +R RS E+ RS S +S K E + H
Sbjct: 487 SSSRSPGPHPRSWSSSRSPSKSRSRSAEKRPHSPSRSPSPKKPLSRDKDGEGRARHSEAE 546
Query: 812 PSTGVRQGSHHEQARDNSRHSASQDGQDTI-----------RGHPGSSRRGRQGSHHEQS 860
+ R+ + R R S S I R P SS + +S
Sbjct: 547 ATRARRRSRSYSPIRKRRRDSPSFMEPRRITSARKRPIPYYRPSPSSSSSCLSSDYSTRS 606
Query: 861 VDRSGHSGSHHSHTTSQGRSDASRGQSGSRSASRTTRNEEQSRDGSRHSG 910
RS G HSH + RS +R S +RS SRT SR S G
Sbjct: 607 HSRSPSPG--HSHGSYSSRSHGTR--SRTRSPSRTPSPSYHSRSSSESGG 652
Score = 81.3 bits (199), Expect = 2e-14
Identities = 126/525 (24%), Positives = 193/525 (36%), Gaps = 64/525 (12%)
Query: 1189 GHSGSHHSHTTSQGRSDASHGQSGSRSASRQTRKDKQSGDGSRHSGSRHHEAASWADSSR 1248
GH G H +S S + + R++RK K+ + GS +
Sbjct: 150 GHRGYRTKHWSSSSASPPPKKKKKKKGGHRRSRK-KRRLESECSCGSSSPLRKKKKSVKK 208
Query: 1249 HSQVGQEQSSGSRTSRHQGSSVSQDSDSERHSDDSERLSGSASRNHHGSSREQSRDGSRH 1308
H + SGSR R S S+ E++ + + S R H RH
Sbjct: 209 HRR--DRSDSGSRRKRRHRSRSSKCKRKEKNKEKKRPHTESPGRRSH-----------RH 255
Query: 1309 PGFHQEDRASHGHSADS---SRQSGTHHTESSSHGQAVSSHEQARSSPGERHGSRHQQSA 1365
+ H +DS SR S H E G SS ++ S G Q++
Sbjct: 256 SSGSSHSPSLSSHYSDSRSPSRLSPKHRDEGRKTGSQRSSGSRSPSPSGGSGWGSPQRNG 315
Query: 1366 DSSRHSGIGHRQASSAVRDSGHRGSSGSQVTNSEGHSEDSDTQSVSAHGQAGPHQQSHKE 1425
S + SG + SA S +V + + + A G+ P +S
Sbjct: 316 GSGQRSGAHGGRPGSAHSPPDKPSSPSPRVRDKAA----AAAPTPPARGKESPSPRS-AP 370
Query: 1426 SARGQSGESSGRSRSFLYQVSSHEQSESTHGQTAPSTGGRQGSRHEQARNSSR-----HS 1480
S++G+ G ++G + + +S S+ +AP GR+ R R SSR S
Sbjct: 371 SSQGRGGRAAGGAGRRRRRRRRRRRSRSS--ASAPRRRGRRRPRPAPPRGSSRSLSRARS 428
Query: 1481 ASQDGQ-----------DTIRGHPGSSRGGRQGSYHEQSVDRSGHSGYHHSHTTPQGRSD 1529
+S G + RGH G + ++ + S G H P+G+S
Sbjct: 429 SSDSGSGRGAPGPGPEPGSERGHGGHGKRAKERPPRARPASTSPSPGAHGRRGGPEGKSS 488
Query: 1530 ASHGQSGPRSASRQ---TRNEEQSGDGSRHSGSRHHEPSTRAGSSRHSQVGQGESAGSKT 1586
+ PRS S +++ +S + HS SR PS + SR G+G + S+
Sbjct: 489 SRSPGPHPRSWSSSRSPSKSRSRSAEKRPHSPSR--SPSPKKPLSRDKD-GEGRARHSEA 545
Query: 1587 ----SRRQGSSVS----QDRDSEGHSEDSERRSESASRNHYGSAREQSRHGSR------N 1632
+RR+ S S + RDS E RR SA + R S +
Sbjct: 546 EATRARRRSRSYSPIRKRRRDSPSFME--PRRITSARKRPIPYYRPSPSSSSSCLSSDYS 603
Query: 1633 PRSHQEDRA-SHGHSAESSRQSGTRHAETSSGGQAASSQEQARSS 1676
RSH + H H + SSR GTR + T S + S +RSS
Sbjct: 604 TRSHSRSPSPGHSHGSYSSRSHGTR-SRTRSPSRTPSPSYHSRSS 647
Score = 80.9 bits (198), Expect = 2e-14
Identities = 129/532 (24%), Positives = 198/532 (37%), Gaps = 72/532 (13%)
Query: 1386 GHRGSSGSQVTNSEGHSEDSDTQSVSAHGQAGPHQQSHKESARGQSGESSGRSRSFLYQV 1445
GHRG ++S + + G H++S K+ R +S S G S +
Sbjct: 150 GHRGYRTKHWSSSSASPPPKKKKK-----KKGGHRRSRKKR-RLESECSCGSSSP----L 199
Query: 1446 SSHEQSESTHGQTAPSTGGRQGSRHEQARNSSRHSASQDGQDTIRGHPGSSRGGRQGSYH 1505
++S H + +G R+ RH SS+ + ++ R H S GR+ H
Sbjct: 200 RKKKKSVKKHRRDRSDSGSRRKRRHRS--RSSKCKRKEKNKEKKRPHTESP--GRRSHRH 255
Query: 1506 EQSVDRSGHSGYHHSHTTPQGRSDASHGQSGPRSASRQTRNEEQSGDGSRHSGSRHHEPS 1565
S H+S + R H G ++ S+ R SGSR PS
Sbjct: 256 SSGSSHSPSLSSHYSDSRSPSRLSPKHRDEGRKTGSQ------------RSSGSRSPSPS 303
Query: 1566 TRAG-SSRHSQVGQGESAGSKTSRRQGSSVSQDRDSEGHSEDSERRSESASRNHYGSARE 1624
+G S G G+ +G+ R + D+ S S R ++A+ AR
Sbjct: 304 GGSGWGSPQRNGGSGQRSGAHGGRPGSAHSPPDKPS---SPSPRVRDKAAAAAPTPPARG 360
Query: 1625 QSRHGSRNPRSHQ--EDRASHGHSAESSRQSGTRHAETSSGGQAASSQEQARSSPGERHG 1682
+ R+ S Q RA+ G R+ R + +S+ + + R +P R
Sbjct: 361 KESPSPRSAPSSQGRGGRAAGGAGRRRRRRRRRRRSRSSASAPRRRGRRRPRPAP-PRGS 419
Query: 1683 SRHQQSADSSTDSGTGRRQ--DSSVVGDSGNRGSSGSQASDSEGHSEESDTQ-SVSAHGQ 1739
SR A SS+DSG+GR G G G +A + + + T S AHG+
Sbjct: 420 SRSLSRARSSSDSGSGRGAPGPGPEPGSERGHGGHGKRAKERPPRARPASTSPSPGAHGR 479
Query: 1740 ------------AGPHQQSHQES-----TRGQSGER----SGRSGSFLYQVSTHEQSES- 1777
GPH +S S +R +S E+ RS S +S + E
Sbjct: 480 RGGPEGKSSSRSPGPHPRSWSSSRSPSKSRSRSAEKRPHSPSRSPSPKKPLSRDKDGEGR 539
Query: 1778 AHGRTGPSTGGRQRSR-----HEQARDSSRH-------SASQEGQDTIRGHPGSSRGGRQ 1825
A +T R+RSR ++ RDS SA + R P SS
Sbjct: 540 ARHSEAEATRARRRSRSYSPIRKRRRDSPSFMEPRRITSARKRPIPYYRPSPSSSSSCLS 599
Query: 1826 GSHYEQSVDSSGHSGSHHSHTTSQERSDVSRGQSGSR--SVSRQTRNEKQSG 1875
+ +S S G H +S+ SR +S SR S S +R+ +SG
Sbjct: 600 SDYSTRSHSRSPSPGHSHGSYSSRSHGTRSRTRSPSRTPSPSYHSRSSSESG 651
Score = 80.5 bits (197), Expect = 3e-14
Identities = 126/526 (23%), Positives = 184/526 (34%), Gaps = 71/526 (13%)
Query: 1861 SRSVSRQTRNEKQSGDGSRHSGSRHHEASSRADSSRHSQVGQGQSSGPRTSRNQGSSVSQ 1920
S S S + +K+ G R S R S+ G SS R + +
Sbjct: 161 SSSASPPPKKKKKKKGGHRRS---------RKKRRLESECSCGSSSPLRKKKKSVKKHRR 211
Query: 1921 DSDSQGHSEDSERWSGSASRNHLGSAWEQSRDGSRHPGSHHEDRAGHGHSADSSRQSGTR 1980
D G S S+ E+ R + PG R H HS+ SS
Sbjct: 212 DRSDSGSRRKRRHRSRSSKCKRKEKNKEKKRPHTESPG-----RRSHRHSSGSSHSPSLS 266
Query: 1981 HTESSSRGQAASSHEQARSSAGERHGSHHQLQSADSSRHSGIGHGQ----ASSAVRDSGH 2036
S SR + S + G + GS S S G G G S R H
Sbjct: 267 SHYSDSRSPSRLSPKHR--DEGRKTGSQRSSGSRSPSPSGGSGWGSPQRNGGSGQRSGAH 324
Query: 2037 RGYSGSQASDSEGHSEDSD---------TQSVSAQGKAGPHQQSHKESARGQSGESSGRS 2087
G GS S + S S + A+GK P +S S++G+ G ++G +
Sbjct: 325 GGRPGSAHSPPDKPSSPSPRVRDKAAAAAPTPPARGKESPSPRS-APSSQGRGGRAAGGA 383
Query: 2088 GSFLYQVSTHEQSESTHGQSAPSTGGRQGSHYDQAQDSSRH-SASQEGQDTIRGHPGPSR 2146
G + +S S+ SAP GR+ + SSR S ++ D+ G P
Sbjct: 384 GRRRRRRRRRRRSRSS--ASAPRRRGRRRPRPAPPRGSSRSLSRARSSSDSGSGRGAPGP 441
Query: 2147 GGRQGSHQEQSVDRSGHSGSHHSHTTSQGRSDASRGQSGSRSASRKTYDKEQSGDGSRHS 2206
G GS + GH G + + R + S S S + + +G S
Sbjct: 442 GPEPGSER-------GHGGH-----GKRAKERPPRARPASTSPSPGAHGRRGGPEGKSSS 489
Query: 2207 GSHHHEASSWADSSRHSLVGQGQSSGPRTSRPRGS-----SVSQDSDSEGHSEDSE---- 2257
S SW+ SSR + +S+ R P S +S+D D EG + SE
Sbjct: 490 RSPGPHPRSWS-SSRSPSKSRSRSAEKRPHSPSRSPSPKKPLSRDKDGEGRARHSEAEAT 548
Query: 2258 ---RRSGSAS-----RNHHGSAQEQSR--DGSRHPRSHHEDRAGHGHSAESSRQSGTHHA 2307
RRS S S R S E R + P ++ S SS S H+
Sbjct: 549 RARRRSRSYSPIRKRRRDSPSFMEPRRITSARKRPIPYYRPSPSSSSSCLSSDYSTRSHS 608
Query: 2308 ENSSGGQAASSHEQARSSAGERHGSHHQQSADSSRHSGIGHGQASS 2353
+ S G + S+ + HG+ + + S S H ++SS
Sbjct: 609 RSPSPGHSHGSY------SSRSHGTRSRTRSPSRTPSPSYHSRSSS 648
Score = 79.0 bits (193), Expect = 9e-14
Identities = 118/512 (23%), Positives = 189/512 (36%), Gaps = 81/512 (15%)
Query: 1213 SRSASRQTRKDKQSGDGSRHSGSRHHEAASWADSSRHSQVGQEQSSGSRTSRHQGSSVSQ 1272
S SAS +K K+ G R S + ++ E S GS + + +
Sbjct: 161 SSSASPPPKKKKKKKGGHRRSRKKR-------------RLESECSCGSSSPLRKKKKSVK 207
Query: 1273 DSDSERHSDDSERLSGSASRNHHGSSREQSRDGSRHPGFHQEDRASHGHSADSSRQSG-- 1330
+R S R SR+ +E++++ R P R SH HS+ SS
Sbjct: 208 KHRRDRSDSGSRRKRRHRSRSSKCKRKEKNKEKKR-PHTESPGRRSHRHSSGSSHSPSLS 266
Query: 1331 THHTESSSHGQAVSSH-EQARSSPGERHGSRHQQSADSSRHSGIGHRQASSAVRDSGHRG 1389
+H+++S S + H ++ R + +R S G R S R H G
Sbjct: 267 SHYSDSRSPSRLSPKHRDEGRKTGSQRSSGSRSPSPSGGSGWGSPQRNGGSGQRSGAHGG 326
Query: 1390 SSGSQVTNSEGHSEDSD---------TQSVSAHGQAGPHQQSHKESARGQSGESSGRSRS 1440
GS + + S S + A G+ P +S S++G+ G ++G +
Sbjct: 327 RPGSAHSPPDKPSSPSPRVRDKAAAAAPTPPARGKESPSPRS-APSSQGRGGRAAGGAGR 385
Query: 1441 FLYQVSSHEQSESTHGQTAPSTGGRQGSRHEQARNSSR-----HSASQDGQD-------- 1487
+ +S S+ +AP GR+ R R SSR S+S G
Sbjct: 386 RRRRRRRRRRSRSS--ASAPRRRGRRRPRPAPPRGSSRSLSRARSSSDSGSGRGAPGPGP 443
Query: 1488 ---TIRGHPGSSRGGRQGSYHEQSVDRSGHSGYHHSHTTPQGRSDASHGQSGPRSASRQ- 1543
+ RGH G + ++ + S G H P+G+S + PRS S
Sbjct: 444 EPGSERGHGGHGKRAKERPPRARPASTSPSPGAHGRRGGPEGKSSSRSPGPHPRSWSSSR 503
Query: 1544 --TRNEEQSGDGSRHSGSRHHEPSTRAGSSRHSQVGQGESAGSKT----SRRQGSSVS-- 1595
+++ +S + HS SR PS + SR G+G + S+ +RR+ S S
Sbjct: 504 SPSKSRSRSAEKRPHSPSR--SPSPKKPLSRDKD-GEGRARHSEAEATRARRRSRSYSPI 560
Query: 1596 --QDRDSEGHSED----SERR------------------SESASRNHYGSAREQSRHGSR 1631
+ RDS E S R+ S+ ++R+H S HGS
Sbjct: 561 RKRRRDSPSFMEPRRITSARKRPIPYYRPSPSSSSSCLSSDYSTRSHSRSPSPGHSHGSY 620
Query: 1632 NPRSHQEDRASHGHSAESSRQSGTRHAETSSG 1663
+ RSH + S S +R + S G
Sbjct: 621 SSRSHGTRSRTRSPSRTPSPSYHSRSSSESGG 652
Score = 77.4 bits (189), Expect = 3e-13
Identities = 117/494 (23%), Positives = 179/494 (36%), Gaps = 50/494 (10%)
Query: 1741 GPHQQSHQESTRGQSGERSGRSGSFLYQVSTHEQSESAHGRTGPSTGGRQRSRH------ 1794
G H++S ++ R E S S S L + ++S H R +G R++ RH
Sbjct: 176 GGHRRSRKK--RRLESECSCGSSSPLRK---KKKSVKKHRRDRSDSGSRRKRRHRSRSSK 230
Query: 1795 ----EQARDSSRHSASQEGQDTIRGHPGSSRGGRQGSHYEQSVDSSGHSGSHHSHTTSQE 1850
E+ ++ R G+ + R GSS SHY S S S H +
Sbjct: 231 CKRKEKNKEKKRPHTESPGRRSHRHSSGSSHSPSLSSHYSDSRSPSRLSPKHR----DEG 286
Query: 1851 RSDVSRGQSGSRSVSRQTRNEKQSGDGSRHSGSRHHEASSRADSSRHSQVGQGQSSGPRT 1910
R S+ SGSRS S + S + SG R R S+ HS + S PR
Sbjct: 287 RKTGSQRSSGSRSPSPSGGSGWGSPQRNGGSGQRSGAHGGRPGSA-HSPPDKPSSPSPRV 345
Query: 1911 SRNQGSSVSQDSDSQGHSEDSERWSGSASRNHLGSAWEQSRDGSRHPGSHHEDRAGHGHS 1970
R++ ++ + ++G S R S +S+ G A G+ R S
Sbjct: 346 -RDKAAAAAPTPPARGKESPSPR-SAPSSQGRGGRA----AGGAGRRRRRRRRRRRSRSS 399
Query: 1971 ADSSRQSGTRHTESSSRGQAASSHEQARSSAGERHGSHHQLQSADSSRHSGIGHGQASSA 2030
A + R+ G R + ++ S +ARSS+ GS S GHG
Sbjct: 400 ASAPRRRGRRRPRPAPPRGSSRSLSRARSSSDS--GSGRGAPGPGPEPGSERGHGGHGKR 457
Query: 2031 VRDSGHRGYSGSQASDSEGHSEDSDTQSVSAQGKAGPHQQSHKES-----ARGQSGE--- 2082
++ R S + H + S+ GPH +S S +R +S E
Sbjct: 458 AKERPPRARPASTSPSPGAHGRRGGPEGKSSSRSPGPHPRSWSSSRSPSKSRSRSAEKRP 517
Query: 2083 -SSGRSGSFLYQVSTHEQSE--STHGQSAPSTGGRQGSHYDQAQDSSRHSASQEGQDTI- 2138
S RS S +S + E + H ++ + R+ Y + R S S I
Sbjct: 518 HSPSRSPSPKKPLSRDKDGEGRARHSEAEATRARRRSRSYSPIRKRRRDSPSFMEPRRIT 577
Query: 2139 ----------RGHPGPSRGGRQGSHQEQSVDRSGHSGSHHSHTTSQGRSDASRGQSGSRS 2188
R P S + +S RS G H +S+ SR +S SR+
Sbjct: 578 SARKRPIPYYRPSPSSSSSCLSSDYSTRSHSRSPSPGHSHGSYSSRSHGTRSRTRSPSRT 637
Query: 2189 ASRKTYDKEQSGDG 2202
S + + S G
Sbjct: 638 PSPSYHSRSSSESG 651
Score = 75.1 bits (183), Expect = 1e-12
Identities = 119/522 (22%), Positives = 187/522 (35%), Gaps = 57/522 (10%)
Query: 3330 SRHWGSSGSQASDSEGHSEESDTQSVSGHGQAGPHQQSHQESARDRSGGRSGRSGSFLYQ 3389
++HW SS + + ++ GH ++ ++ E + S + S
Sbjct: 156 TKHWSSSSASPPPKKKKKKKG------GHRRSRKKRRLESECSCGSSSPLRKKKKS---- 205
Query: 3390 VSTHEQSESAHGRTRTSTGRRQGS---HHEQARDSSRHSASQEGQDTIRGHPGSSRRGRQ 3446
V H + S G R R + S E+ ++ R G+ + R GSS
Sbjct: 206 VKKHRRDRSDSGSRRKRRHRSRSSKCKRKEKNKEKKRPHTESPGRRSHRHSSGSSHSPSL 265
Query: 3447 GSHYEQSVDRSGHSGSHHSHTTSQGRSDASRGQSGSRSASRQ----TRNDEQSGDGSRHS 3502
SHY S S S H +GR S+ SGSRS S + +++G + S
Sbjct: 266 SSHYSDSRSPSRLSPKHR----DEGRKTGSQRSSGSRSPSPSGGSGWGSPQRNGGSGQRS 321
Query: 3503 WSHHHEASTQADSSRHSQSGQGQSAGPRTSRNQGSSVSQDSDSQGHSEDSERWSGSASRN 3562
+H S HS + S PR R++ ++ + ++G S R S +S+
Sbjct: 322 GAHGGR-----PGSAHSPPDKPSSPSPRV-RDKAAAAAPTPPARGKESPSPR-SAPSSQG 374
Query: 3563 HRGSAQEQSRDGSRHPTSHHEDRAGHGHSAESSRQSGTHHAENSSGGQAASSHEQARSSA 3622
G A + R R+ SA + R+ G + ++ S +ARSS+
Sbjct: 375 RGGRAAGGAGRRRRRRRRRRRSRS----SASAPRRRGRRRPRPAPPRGSSRSLSRARSSS 430
Query: 3623 GERHGSHHQQSADSSRHSGIGHGQASSAVRDSGHRGSSGSQASDSEGHSEDSDTQSVSAH 3682
G S GHG ++ R S + H + S+
Sbjct: 431 DSGSG-RGAPGPGPEPGSERGHGGHGKRAKERPPRARPASTSPSPGAHGRRGGPEGKSSS 489
Query: 3683 GQAGPHQQSHQES-----TRGRSAGR----SGRSGSFLYQVSTHEQSES-AHGRAGPSTG 3732
GPH +S S +R RSA + RS S +S + E A +T
Sbjct: 490 RSPGPHPRSWSSSRSPSKSRSRSAEKRPHSPSRSPSPKKPLSRDKDGEGRARHSEAEATR 549
Query: 3733 GRQGSR-----HEQARDSSRH-------SASQEGQDTIRGHPGSRRGGRQGSYHEQSVDR 3780
R+ SR ++ RDS SA + R P S Y +S R
Sbjct: 550 ARRRSRSYSPIRKRRRDSPSFMEPRRITSARKRPIPYYRPSPSSSSSCLSSDYSTRSHSR 609
Query: 3781 SGHSGSHHSHTTSQGRSDASHGQSGSR--SASRETRNEEQSG 3820
S G H +S+ S +S SR S S +R+ +SG
Sbjct: 610 SPSPGHSHGSYSSRSHGTRSRTRSPSRTPSPSYHSRSSSESG 651
Score = 74.7 bits (182), Expect = 2e-12
Identities = 134/564 (23%), Positives = 186/564 (32%), Gaps = 96/564 (17%)
Query: 540 GHSGSHHSHTTSQGRSDA----SHGQSGSRSASRQTRNEEQSGDGT-------RHSGSRH 588
GH G H +S S + G R + ++ R E + G+ + S +H
Sbjct: 150 GHRGYRTKHWSSSSASPPPKKKKKKKGGHRRSRKKRRLESECSCGSSSPLRKKKKSVKKH 209
Query: 589 HEASSQADSSRHSQVGQGQSSGPRTSRNQGSSVSQDSDSQGHSEDSERWSGSASRNHHGS 648
S + S R + S R +N+ ++S G SGS+ S
Sbjct: 210 RRDRSDSGSRRKRRHRSRSSKCKRKEKNKEKK-RPHTESPGRRSHRHS-SGSSHSPSLSS 267
Query: 649 AQEQSRDGSRHPRSHHEDRAGHGHSADSSRKSGTRHTQNSSSGQAASSHEQARSSAGERH 708
SR SR H ++ G S R SG+R S SG + Q +G+R
Sbjct: 268 HYSDSRSPSRLSPKHRDE----GRKTGSQRSSGSRSP--SPSGGSGWGSPQRNGGSGQRS 321
Query: 709 GSRHQLQSADSSRHSGTGHGQASSA-VRDSGHRGSSGSQATDSEGHSEDSDTQSVSGHGQ 767
G+ S HS + S VRD + A E S S S G+
Sbjct: 322 GAHG---GRPGSAHSPPDKPSSPSPRVRDKAAAAAPTPPARGKESPSPRSAPSSQGRGGR 378
Query: 768 A----GHHQQSHQESARDRSG-----ERSRRS-------GSFLYQVSTHKQSESSHGWTG 811
A G ++ + R RS R RR GS S+S G
Sbjct: 379 AAGGAGRRRRRRRRRRRSRSSASAPRRRGRRRPRPAPPRGSSRSLSRARSSSDSGSGRGA 438
Query: 812 PSTGVRQGSHHEQARDNSRHSASQDGQDTIRGHPGSSRRGRQGSHHEQSVDRSGHSGSHH 871
P G GS RGH G +R ++ + S G+H
Sbjct: 439 PGPGPEPGSE--------------------RGHGGHGKRAKERPPRARPASTSPSPGAH- 477
Query: 872 SHTTSQGRSDASRGQSGSRSASRTTRNEEQSRDGSRHSGSRHHEASSHADISRHSQAGQG 931
GR G+S SRS R+ SR S+ S SR E H+ S
Sbjct: 478 ------GRRGGPEGKSSSRSPGPHPRSWSSSRSPSK-SRSRSAEKRPHSPSRSPSPK--- 527
Query: 932 QSEGSRTSRRQGSSVSQDSDSEGHSEDSERWSGSASRNHRGSAQEQSRHGSRHPRSHHED 991
+S+D D EG + SE + A R R + + R R S E
Sbjct: 528 ------------KPLSRDKDGEGRARHSEAEATRARRRSRSYSPIRKRR--RDSPSFMEP 573
Query: 992 RAGHGHSADSSRQSGTPH--AETSSGGQAASSHEQARS-----SPGERHGSRHQQSADSS 1044
R S+R+ P+ SS SS RS SPG HGS +S +
Sbjct: 574 RR-----ITSARKRPIPYYRPSPSSSSSCLSSDYSTRSHSRSPSPGHSHGSYSSRSHGTR 628
Query: 1045 RHSGIPRRQASSAVRDSGHWGSSG 1068
+ P R S + S G
Sbjct: 629 SRTRSPSRTPSPSYHSRSSSESGG 652
Score = 74.3 bits (181), Expect = 2e-12
Identities = 123/539 (22%), Positives = 191/539 (35%), Gaps = 86/539 (15%)
Query: 3007 GHRGYSGSQASDNEGHSEDSDTQSVSAHGQAGSHQQSHQESARGRSGETSGHSGSFLYQV 3066
GHRGY S + + + G H++S ++ R E S S S L +
Sbjct: 150 GHRGYRTKHWSSSSASPPPKKKKK-----KKGGHRRSRKK--RRLESECSCGSSSPLRK- 201
Query: 3067 STHEQSESSHGWTGPSTRGRQGSRHEQAQDSSRHSASQYGQDTIRGHPGSSRGGRQGYHH 3126
++S H R GSR ++ S + ++ + P + GR+ + H
Sbjct: 202 --KKKSVKKHR----RDRSDSGSRRKRRHRSRSSKCKRKEKNKEKKRPHTESPGRRSHRH 255
Query: 3127 EHSVDSSGHSGSHHSHTTS----------QGRSDASRGQSGSRSASRTTRN-----EEQS 3171
S SH+S + S +GR S+ SGSRS S + + +
Sbjct: 256 SSGSSHSPSLSSHYSDSRSPSRLSPKHRDEGRKTGSQRSSGSRSPSPSGGSGWGSPQRNG 315
Query: 3172 GDSSRHSVSRHHEASTHADISRHSQAVQGQSEGSRRSRRQGSSVSQDSDSEGHSEDSERW 3231
G R S H+ + S + + + + ++S S + S+
Sbjct: 316 GSGQRSGAHGGRPGSAHSPPDKPSSPSPRVRDKAAAAAPTPPARGKESPSPRSAPSSQGR 375
Query: 3232 SGSAS-------------RNHRGSVQEQSRHGSRHPRSHHEDRAGHGHSADRSRQSGTRH 3278
G A+ R R S R G R PR G S R+R S
Sbjct: 376 GGRAAGGAGRRRRRRRRRRRSRSSASAPRRRGRRRPRP--APPRGSSRSLSRARSS---- 429
Query: 3279 AETSSGGQAASSHEQARSSPGE-RHGSRHQQSADSSRHSGIPRGQASSAVRDSRHWGSSG 3337
+++ SG A + S G HG R ++ +R P + S R G G
Sbjct: 430 SDSGSGRGAPGPGPEPGSERGHGGHGKRAKERPPRAR----PASTSPSPGAHGRRGGPEG 485
Query: 3338 SQASDSEG------HSEESDTQSVSGHGQAGPHQQSHQES-----ARDRSGGRSGRSGSF 3386
+S S G S S ++S S + PH S S +RD+ G GR
Sbjct: 486 KSSSRSPGPHPRSWSSSRSPSKSRSRSAEKRPHSPSRSPSPKKPLSRDKDG--EGR---- 539
Query: 3387 LYQVSTHEQSESAHGRTRTSTGRRQGSHHEQARDSSRH-------SASQEGQDTIRGHPG 3439
+ H ++E+ R R+ R ++ RDS SA + R P
Sbjct: 540 ----ARHSEAEATRARRRS---RSYSPIRKRRRDSPSFMEPRRITSARKRPIPYYRPSPS 592
Query: 3440 SSRRGRQGSHYEQSVDRSGHSGSHHSHTTSQGRSDASRGQSGSR--SASRQTRNDEQSG 3496
SS + +S RS G H +S+ SR +S SR S S +R+ +SG
Sbjct: 593 SSSSCLSSDYSTRSHSRSPSPGHSHGSYSSRSHGTRSRTRSPSRTPSPSYHSRSSSESG 651
Score = 73.9 bits (180), Expect = 3e-12
Identities = 110/472 (23%), Positives = 160/472 (33%), Gaps = 68/472 (14%)
Query: 1125 EQSESAHGRTRTSTGRRQGSHHEQARDSSRHSASQEGQDTIRAHPGSRRGGRQGSHHEQS 1184
++S H R R+ +G R+ H SS+ ++ ++ R H S GR+ H
Sbjct: 203 KKSVKKHRRDRSDSGSRRKRRHRSR--SSKCKRKEKNKEKKRPHTESP--GRRSHRHSSG 258
Query: 1185 VDRSGHSGSHHSHTTSQGRSDASHGQSGSRSASRQTRKDKQSGDGSRHSGSRHHE---AA 1241
S SH+S + S R H G ++ S+ R SGSR +
Sbjct: 259 SSHSPSLSSHYSDSRSPSRLSPKHRDEGRKTGSQ------------RSSGSRSPSPSGGS 306
Query: 1242 SWADSSRHSQVGQEQSSGSRTSRHQGSSVSQDSDSERHSDDSERL---SGSASRNHHGSS 1298
W R+ SG R+ H G S S ++ S S R+ + +A+
Sbjct: 307 GWGSPQRNG------GSGQRSGAHGGRPGSAHSPPDKPSSPSPRVRDKAAAAAPTPPARG 360
Query: 1299 REQSRDGSRHPGFHQEDRASHGHSADSSRQSGTHHTESSSHGQAVSSHEQARSSPGERHG 1358
+E S + RA+ G R+ + SS+ + R +P R
Sbjct: 361 KESPSPRSAPSSQGRGGRAAGGAGRRRRRRRRRRRSRSSASAPRRRGRRRPRPAP-PRGS 419
Query: 1359 SRHQQSADSSRHSGIGHRQASSAVRDSGHRGSSGSQVTNSEGHSE---DSDTQSVSAHG- 1414
SR A SS SG G RG G E S + S AHG
Sbjct: 420 SRSLSRARSSSDSGSGRGAPGPGPEPGSERGHGGHGKRAKERPPRARPASTSPSPGAHGR 479
Query: 1415 QAGPHQQS-------HKESARGQSGESSGRSRSFLYQVSSHEQSESTHGQTAPSTGGRQG 1467
+ GP +S H S S RSRS + S +S S + G
Sbjct: 480 RGGPEGKSSSRSPGPHPRSWSSSRSPSKSRSRSAEKRPHSPSRSPSPKKPLSRDKDGEGR 539
Query: 1468 SRHEQ-----ARNSSRH---------------------SASQDGQDTIRGHPGSSRGGRQ 1501
+RH + AR SR SA + R P SS
Sbjct: 540 ARHSEAEATRARRRSRSYSPIRKRRRDSPSFMEPRRITSARKRPIPYYRPSPSSSSSCLS 599
Query: 1502 GSYHEQSVDRSGHSGYHHSHTTPQGRSDASHGQSGPR--SASRQTRNEEQSG 1551
Y +S RS G+ H + + S +S R S S +R+ +SG
Sbjct: 600 SDYSTRSHSRSPSPGHSHGSYSSRSHGTRSRTRSPSRTPSPSYHSRSSSESG 651
Score = 72.0 bits (175), Expect = 1e-11
Identities = 142/596 (23%), Positives = 205/596 (34%), Gaps = 101/596 (16%)
Query: 749 DSEGHSEDSDTQSVSGHGQAGHHQQSHQESARDRSGERSRRSGSFLYQVSTHKQSESSHG 808
D + D D + G G+ + H S+ + ++ ++ S K+ S
Sbjct: 133 DDDDGPVDCDCPASCYRGHRGYRTK-HWSSSSASPPPKKKKKKKGGHRRSRKKRRLESEC 191
Query: 809 WTGPSTGVRQGSHHEQARDNSRHSASQDGQDTIRGHPGSSRRGRQGSHHEQSVDRSGHSG 868
G S+ +R+ +++ R S G R H S + ++ +++ S
Sbjct: 192 SCGSSSPLRK---KKKSVKKHRRDRSDSGSRRKRRHRSRSSKCKRKEKNKEKKRPHTESP 248
Query: 869 SHHSHTTSQGRSDA---SRGQSGSRSASRTTRNEEQSRDGSRHSGSRHHEASSHADISRH 925
SH S G S + S S SRS SR + + RD R +GS+
Sbjct: 249 GRRSHRHSSGSSHSPSLSSHYSDSRSPSRLS---PKHRDEGRKTGSQ------------- 292
Query: 926 SQAGQGQSEGSRTSRRQGSSVSQDSDSEGHSEDSERWSGSASRNHRGSAQEQSRHGSRHP 985
+S GSR+ G S W GS RN GS Q HG R
Sbjct: 293 ------RSSGSRSPSPSGGS---------------GW-GSPQRN-GGSGQRSGAHGGRPG 329
Query: 986 RSHH------------EDRAGHGHSADSSR--QSGTPHAETSS---GGQAASSHEQARSS 1028
+H D+A +R +S +P + SS GG+AA + R
Sbjct: 330 SAHSPPDKPSSPSPRVRDKAAAAAPTPPARGKESPSPRSAPSSQGRGGRAAGGAGRRRRR 389
Query: 1029 PGERHGSRHQQSADSSRHSGIPRRQASSAVRDSGHWGSSGSQASDSEGHSEESDTQSVSG 1088
R SR SA PRR+ R + GSS S + S + S SG
Sbjct: 390 RRRRRRSRSSASA--------PRRRGRRRPRPAPPRGSSRSLS------RARSSSDSGSG 435
Query: 1089 HGQDGPHQQSHQESARDWSGGRSGRSGSFIYQVSTHEQSESAHGR----TRTSTGRRQGS 1144
G GP + E G R+ ST S AHGR S+ R G
Sbjct: 436 RGAPGPGPEPGSERGHGGHGKRAKERPPRARPAST-SPSPGAHGRRGGPEGKSSSRSPGP 494
Query: 1145 HHEQARDSSRHSASQEGQDTIRAHPGSRRGGRQGSHHEQSVDRSGHSGSHHSHTTSQGRS 1204
H S S S+ R H SR S D+ G + H S+ +
Sbjct: 495 HPRSWSSSRSPSKSRSRSAEKRPHSPSR---SPSPKKPLSRDKDGEGRARH----SEAEA 547
Query: 1205 DASHGQSGSRSASRQTRKDKQSGDGSRHSGSRHHEAASWADSSRHSQVGQEQSSGSRTSR 1264
+ +S S S R+ R+D S R S+R + + S S +S
Sbjct: 548 TRARRRSRSYSPIRKRRRDSPSFMEPRR-----------ITSARKRPIPYYRPSPSSSSS 596
Query: 1265 HQGSSVSQDSDSERHSDDSERLSGSASRNHHGSSREQSRDGSRHPGFHQEDRASHG 1320
S S S S S S S SR+H SR +S + P +H + G
Sbjct: 597 CLSSDYSTRSHSRSPSPGHSHGSYS-SRSHGTRSRTRSPSRTPSPSYHSRSSSESG 651
Score = 72.0 bits (175), Expect = 1e-11
Identities = 123/530 (23%), Positives = 172/530 (32%), Gaps = 62/530 (11%)
Query: 1289 SASRNHHG--SSREQSRDGSRHPGFHQEDRASHGHSADSSRQSGTHHTESSS----HGQA 1342
S R H G + S S P ++ + H S R SSS ++
Sbjct: 146 SCYRGHRGYRTKHWSSSSASPPPKKKKKKKGGHRRSRKKRRLESECSCGSSSPLRKKKKS 205
Query: 1343 VSSHEQARSSPGERHGSRHQQSADSSRHSGIGHRQASSAVRDSG---HRGSSGSQVTNS- 1398
V H + RS G R RH+ + + + G HR SSGS + S
Sbjct: 206 VKKHRRDRSDSGSRRKRRHRSRSSKCKRKEKNKEKKRPHTESPGRRSHRHSSGSSHSPSL 265
Query: 1399 EGHSEDSDTQSVSAHGQAGPHQQSHKESARGQSGESSGRSRSFLYQVSS---HEQSESTH 1455
H DS + S + P H++ R + S SRS S Q
Sbjct: 266 SSHYSDSRSPS-----RLSP---KHRDEGRKTGSQRSSGSRSPSPSGGSGWGSPQRNGGS 317
Query: 1456 GQTAPSTGGRQGSRHEQARNSSRHSASQDGQDTIRGHPGSSRGGRQGSYHEQSVDRSGHS 1515
GQ + + GGR GS H S S + +RG E RS S
Sbjct: 318 GQRSGAHGGRPGSAHSPPDKPSSPSPRVRDKAAAAAPTPPARG------KESPSPRSAPS 371
Query: 1516 GYHHSHTTPQGRSDASHGQSGPRSASRQTRNEEQ-SGDGSRHSGSRHHEPSTRAGSSRHS 1574
QGR + G +G R R+ R + S R G R P+ GSSR
Sbjct: 372 S--------QGRGGRAAGGAGRRRRRRRRRRRSRSSASAPRRRGRRRPRPAPPRGSSR-- 421
Query: 1575 QVGQGESAGSKTSRRQGSSVSQDRDSE-GHSEDSERRSESASRNHYGSAR----EQSRHG 1629
+ + S+ S R + SE GH +R E R S R G
Sbjct: 422 SLSRARSSSDSGSGRGAPGPGPEPGSERGHGGHGKRAKERPPRARPASTSPSPGAHGRRG 481
Query: 1630 SRNPRSHQEDRASHGHSAESSRQSGTRHAETSSGGQAASSQEQARSSPGERHGSRHQQSA 1689
+S H S SSR + ++ + S+ + P R ++
Sbjct: 482 GPEGKSSSRSPGPHPRSWSSSRSPSKSRSRSAEKRPHSPSRSPSPKKPLSRDKDGEGRAR 541
Query: 1690 DSSTDSGTGRRQDSSVVGDSGNRGSSGS------------------QASDSEGHSEESDT 1731
S ++ RR+ S R S S + S S S S
Sbjct: 542 HSEAEATRARRRSRSYSPIRKRRRDSPSFMEPRRITSARKRPIPYYRPSPSSSSSCLSSD 601
Query: 1732 QSVSAHGQAGPHQQSHQESTRGQSGERS-GRSGSFLYQVSTHEQSESAHG 1780
S +H ++ SH + G RS RS S S H +S S G
Sbjct: 602 YSTRSHSRSPSPGHSHGSYSSRSHGTRSRTRSPSRTPSPSYHSRSSSESG 651
Score = 69.7 bits (169), Expect = 6e-11
Identities = 122/530 (23%), Positives = 186/530 (35%), Gaps = 61/530 (11%)
Query: 1613 SASRNHYGSAREQSRHGSRNPRSHQEDRASHGHSAESSRQSGTRHAETSSGG-------- 1664
S R H G + S +P ++ + GH SR+ +E S G
Sbjct: 146 SCYRGHRGYRTKHWSSSSASPPPKKKKKKKGGH--RRSRKKRRLESECSCGSSSPLRKKK 203
Query: 1665 QAASSQEQARSSPGERHGSRHQQSADS---STDSGTGRRQDSSVVGDSGNRGSSGSQASD 1721
++ + RS G R RH+ + + +R + G +R SSGS S
Sbjct: 204 KSVKKHRRDRSDSGSRRKRRHRSRSSKCKRKEKNKEKKRPHTESPGRRSHRHSSGSSHSP 263
Query: 1722 SEGHSEESDTQSVS----AHGQAGPHQQSHQESTRGQSGERSGRSGSFLYQVSTHEQSES 1777
S S SD++S S H G + Q S+ +S SG SG Q
Sbjct: 264 SLS-SHYSDSRSPSRLSPKHRDEG-RKTGSQRSSGSRSPSPSGGSG------WGSPQRNG 315
Query: 1778 AHGRTGPSTGGRQRSRHE----------QARDSS-----------RHSASQEGQDTIRGH 1816
G+ + GGR S H + RD + + S S + +G
Sbjct: 316 GSGQRSGAHGGRPGSAHSPPDKPSSPSPRVRDKAAAAAPTPPARGKESPSPRSAPSSQGR 375
Query: 1817 PGSSRGGRQGSHYEQSVDSSGHSGSHHSHTTSQERSDVSRGQSGSRSVSRQTRNEKQSGD 1876
G + GG + S + + R + + SRS+SR R+ SG
Sbjct: 376 GGRAAGGAGRRRRRRRRRRRSRSSASAPRRRGRRRPRPAPPRGSSRSLSR-ARSSSDSGS 434
Query: 1877 GSRHSGSRHHEASSRADSSRHSQVGQGQSSGPRTSRNQGSSVSQDSDSQGHSEDSERWSG 1936
G G S R G G+ + R R + +S S + G E S
Sbjct: 435 GRGAPGPGPEPGSERGHG------GHGKRAKERPPRARPASTSPSPGAHGRRGGPEGKSS 488
Query: 1937 SASRNHLGSAWEQSRDGSRHPGSHHEDRAGHGHSADSSRQSGTRHTESSSRGQAASSHEQ 1996
S S +W SR S+ E R + S ++ +R + G+ + H +
Sbjct: 489 SRSPGPHPRSWSSSRSPSKSRSRSAEKRPHSPSRSPSPKKPLSRDKD----GEGRARHSE 544
Query: 1997 ARSS-AGERHGSHHQLQSADSSRHSGIGHGQASSAVRDSGHRGYSGSQASDSEGHSEDSD 2055
A ++ A R S+ ++ S + + +SA R Y S +S S S D
Sbjct: 545 AEATRARRRSRSYSPIRKRRRDSPSFMEPRRITSA-RKRPIPYYRPSPSSSSSCLSSDYS 603
Query: 2056 TQSVSAQGKAGPHQQSHKESARGQSGESSGRSGSFLYQVSTHEQSESTHG 2105
T+S S G S+ S+R S RS S S H +S S G
Sbjct: 604 TRSHSRSPSPGHSHGSY--SSRSHGTRSRTRSPSRTPSPSYHSRSSSESG 651
Score = 69.3 bits (168), Expect = 7e-11
Identities = 121/550 (22%), Positives = 177/550 (32%), Gaps = 93/550 (16%)
Query: 3234 SASRNHRG--SVQEQSRHGSRHPRSHHEDRAGHGHSADRSRQSGTRHAETSSGG------ 3285
S R HRG + S S P+ + + GH RSR+ +E S G
Sbjct: 146 SCYRGHRGYRTKHWSSSSASPPPKKKKKKKGGH----RRSRKKRRLESECSCGSSSPLRK 201
Query: 3286 --QAASSHEQARSSPGERHGSRHQQSADSSRHSGIPRGQ-----ASSAVRDSRHWGSSGS 3338
++ H + RS G R RH+ + + + + S R RH S
Sbjct: 202 KKKSVKKHRRDRSDSGSRRKRRHRSRSSKCKRKEKNKEKKRPHTESPGRRSHRHSSGSSH 261
Query: 3339 QASDSEGHSEESDTQSVSGHGQAGPHQQSHQESARDRSGGRSGRSGSFLYQVSTHEQSES 3398
S S +S+ +S + + Q S+ RS SG SG S
Sbjct: 262 SPSLSSHYSDSRSPSRLSPKHRDEGRKTGSQRSSGSRSPSPSGGSG---------WGSPQ 312
Query: 3399 AHGRTRTSTGRRQGSHHEQARDSSRHSASQEGQDTIRGHPGSSRRGRQGSHYEQSVDRSG 3458
+G +G+R G+H R S HS + P R + + R
Sbjct: 313 RNG----GSGQRSGAH--GGRPGSAHSPPDKPSS-----PSPRVRDKAAAAAPTPPARGK 361
Query: 3459 HSGSHHSHTTSQGRSDASRGQSGSRSASRQTRNDEQSG------DGSRHSWSHHHEASTQ 3512
S S S +SQGR + G +G R R+ R +S G R S++
Sbjct: 362 ESPSPRSAPSSQGRGGRAAGGAGRRRRRRRRRRRSRSSASAPRRRGRRRPRPAPPRGSSR 421
Query: 3513 ADSSRHSQSGQGQSAG-------PRTSRNQGSSVSQDSDSQGHSEDSERWSGSASRNHRG 3565
+ S S S G G P + R G + + + + + RG
Sbjct: 422 SLSRARSSSDSGSGRGAPGPGPEPGSERGHGGHGKRAKERPPRARPASTSPSPGAHGRRG 481
Query: 3566 --SAQEQSRDGSRHPTSHHEDRAGHGHSAESSRQSGTHHAENSSGGQAASSHEQARSSAG 3623
+ SR HP S R S SR +S + +R G
Sbjct: 482 GPEGKSSSRSPGPHPRSWSSSR-----SPSKSRSRSAEKRPHSPSRSPSPKKPLSRDKDG 536
Query: 3624 ERHGSHHQQSADSSRHSGIGHGQASSAVRDS-----GHRGSSG----------SQASDSE 3668
E H + A +R + RDS R +S S +S S
Sbjct: 537 EGRARHSEAEATRARRRSRSYSPIRKRRRDSPSFMEPRRITSARKRPIPYYRPSPSSSSS 596
Query: 3669 GHSEDSDTQSVS-----AHGQAGPHQQSHQESTRGRSAGRSGRSGSFLYQVSTHEQSESA 3723
S D T+S S H +SH +R RS R+ S S
Sbjct: 597 CLSSDYSTRSHSRSPSPGHSHGSYSSRSHGTRSRTRSPSRT--------------PSPSY 642
Query: 3724 HGRAGPSTGG 3733
H R+ +GG
Sbjct: 643 HSRSSSESGG 652
Score = 68.6 bits (166), Expect = 1e-10
Identities = 116/524 (22%), Positives = 181/524 (34%), Gaps = 70/524 (13%)
Query: 2810 GHSGSHHSHTTSQGRSDASRGQSGSRSASRTTRNEEQSGDGSRHSGSRHHEASTHADISR 2869
GH G H +S S + + + R +R + + + GS + +
Sbjct: 150 GHRGYRTKHWSSSSASPPPKKKKKKKGGHRRSRKKRRL-ESECSCGSSSPLRKKKKSVKK 208
Query: 2870 HSQAVQGQSEGSRRSRRQGSSVSQDSDSEGHSEDSERWSGSASRNHHGSAQEQLRDGSRH 2929
H + GSRR RR S S+ E + E + S R H + GS H
Sbjct: 209 HRR--DRSDSGSRRKRRHRSRSSKCKRKEKNKEKKRPHTESPGRRSHRHSS-----GSSH 261
Query: 2930 P---RSHQEDRAGHGHSADSSRQSGTRHTQTSSGGQAASSHEQARSSAGERHGSHHQQSA 2986
SH D + R G + +G Q +S S G GS Q++
Sbjct: 262 SPSLSSHYSDSRSPSRLSPKHRDEGRK-----TGSQRSSGSRSPSPSGGSGWGSP-QRNG 315
Query: 2987 DSSRHSGIGHGQASSAVRDSGHRGYSGSQASDNEGHSEDSDTQSVSAHGQAGSHQQSHQE 3046
S + SG G+ SA + D + + A G+ +S
Sbjct: 316 GSGQRSGAHGGRPGSAHSPPDKPSSPSPRVRDKAAAAAPTPP----ARGKESPSPRS-AP 370
Query: 3047 SARGRSGETSGHSGSFLYQVSTHEQSESSHGWTGPSTRGRQGSRHEQAQDSSR-----HS 3101
S++GR G +G +G + +S SS + P RGR+ R + SSR S
Sbjct: 371 SSQGRGGRAAGGAGRRRRRRRRRRRSRSSA--SAPRRRGRRRPRPAPPRGSSRSLSRARS 428
Query: 3102 ASQYGQD-----------TIRGHPGSSRGGRQGYHHEHSVDSSGHSGSHHSHTTSQGRSD 3150
+S G + RGH G + ++ +S G+H +G+S
Sbjct: 429 SSDSGSGRGAPGPGPEPGSERGHGGHGKRAKERPPRARPASTSPSPGAHGRRGGPEGKSS 488
Query: 3151 AS------RGQSGSRSASRT-TRNEEQSGDSSRHSVSRHHEASTHADISRHSQAVQGQSE 3203
+ R S SRS S++ +R+ E+ S S S S D ++ + ++
Sbjct: 489 SRSPGPHPRSWSSSRSPSKSRSRSAEKRPHSPSRSPSPKKPLSRDKDGEGRARHSEAEAT 548
Query: 3204 GSRRSRRQGSSVSQ---DSDS--------------------EGHSEDSERWSGSASRNHR 3240
+RR R S + + DS S S S S ++R+H
Sbjct: 549 RARRRSRSYSPIRKRRRDSPSFMEPRRITSARKRPIPYYRPSPSSSSSCLSSDYSTRSHS 608
Query: 3241 GSVQEQSRHGSRHPRSHHEDRAGHGHSADRSRQSGTRHAETSSG 3284
S HGS RSH S S +R + S G
Sbjct: 609 RSPSPGHSHGSYSSRSHGTRSRTRSPSRTPSPSYHSRSSSESGG 652
Score = 67.0 bits (162), Expect = 4e-10
Identities = 119/529 (22%), Positives = 187/529 (35%), Gaps = 66/529 (12%)
Query: 2683 GHRGYSGSQASDNEGHSEDSDTQSVSAHGQAGSHQQSHQESARGRSGETSGHSGSFLYQV 2742
GHRGY S + + + G H++S ++ R E S S S L +
Sbjct: 150 GHRGYRTKHWSSSSASPPPKKKKK-----KKGGHRRSRKK--RRLESECSCGSSSPLRK- 201
Query: 2743 STHEQSESSHGWTGPSTRGRQGSRHEQAQDSSRHSASQDGQDTIRGHPGSSRGGRQGYHH 2802
++S H R GSR ++ S + ++ + P + GR+ + H
Sbjct: 202 --KKKSVKKHR----RDRSDSGSRRKRRHRSRSSKCKRKEKNKEKKRPHTESPGRRSHRH 255
Query: 2803 EHSVDSSGHSGSHHSHTTS----------QGRSDASRGQSGSRSASRTTRN-----EEQS 2847
S SH+S + S +GR S+ SGSRS S + + +
Sbjct: 256 SSGSSHSPSLSSHYSDSRSPSRLSPKHRDEGRKTGSQRSSGSRSPSPSGGSGWGSPQRNG 315
Query: 2848 GDGSRHSGSRHHEASTHADISRHSQAVQGQSEGSRRSRRQGSSVSQDSDSEGHSEDSERW 2907
G G R S H+ + S S R R + ++ + + G S R
Sbjct: 316 GSGQRSGAHGGRPGSAHSPPDK-------PSSPSPRVRDKAAAAAPTPPARGKESPSPR- 367
Query: 2908 SGSASRNHHGSAQEQLRDGSRHPRSHQEDRAGHGHSADSSRQSGTRHTQTSSGGQAASSH 2967
S +S+ G A G+ R + R SA + R+ G R + + ++ S
Sbjct: 368 SAPSSQGRGGRA----AGGAGRRRRRRRRRRRSRSSASAPRRRGRRRPRPAPPRGSSRSL 423
Query: 2968 EQARSSAGERHGSHHQQSADSSRHSGIGHGQASSAVRDSGHRGYSGSQASDNEGHSEDSD 3027
+ARSS+ G S GHG ++ R S + H
Sbjct: 424 SRARSSSDSGSG-RGAPGPGPEPGSERGHGGHGKRAKERPPRARPASTSPSPGAHGRRGG 482
Query: 3028 TQSVSAHGQAGSHQQSHQES-----ARGRSGETSGHSGSF----LYQVSTHEQSES-SHG 3077
+ S+ G H +S S +R RS E HS S +S + E +
Sbjct: 483 PEGKSSSRSPGPHPRSWSSSRSPSKSRSRSAEKRPHSPSRSPSPKKPLSRDKDGEGRARH 542
Query: 3078 WTGPSTRGRQGSR-----HEQAQDSSRH-------SASQYGQDTIRGHPGSSRGGRQGYH 3125
+TR R+ SR ++ +DS SA + R P SS +
Sbjct: 543 SEAEATRARRRSRSYSPIRKRRRDSPSFMEPRRITSARKRPIPYYRPSPSSSSSCLSSDY 602
Query: 3126 HEHSVDSSGHSGSHHSHTTSQGRSDASRGQSGSR--SASRTTRNEEQSG 3172
S S G H +S+ SR +S SR S S +R+ +SG
Sbjct: 603 STRSHSRSPSPGHSHGSYSSRSHGTRSRTRSPSRTPSPSYHSRSSSESG 651
Score = 66.6 bits (161), Expect = 5e-10
Identities = 113/523 (21%), Positives = 186/523 (35%), Gaps = 52/523 (9%)
Query: 2359 GHRGSSGSQASDSEGHSEDSDTQSVSAHGQAGPHQQSHQESTRGRSAGRSGRSGSFLYQV 2418
GHRG S S + + G H++S ++ R S G S +
Sbjct: 150 GHRGYRTKHWSSSSASPPPKKKKK-----KKGGHRRSRKKR-RLESECSCGSSSP----L 199
Query: 2419 STHEQSESAHGRTGTSTGGRQGSHHKQARDSSRHSTSQEGQDTIHGHPGSSSGGRQGSHY 2478
++S H R + +G R+ H+ + + + P + S GR+ +
Sbjct: 200 RKKKKSVKKHRRDRSDSGSRRKRRHRSRSSKCKRKEKNKEKK----RPHTESPGRRSHRH 255
Query: 2479 EQLVDRSGHSGSHHSHTTSQGRSDASHGHSGSRSASRQ---TRNDEQSGDGSRHSGSRHH 2535
S SH+S + S R H G ++ S++ +R+ SG S R+
Sbjct: 256 SSGSSHSPSLSSHYSDSRSPSRLSPKHRDEGRKTGSQRSSGSRSPSPSGGSGWGSPQRNG 315
Query: 2536 EASSRADSSG------HSQVGQGQSEGPRTSRNWGSSFSQDSDSQGHSEDSERWSGSASR 2589
+ R+ + G HS + S PR R+ ++ + ++G S R S +S+
Sbjct: 316 GSGQRSGAHGGRPGSAHSPPDKPSSPSPRV-RDKAAAAAPTPPARGKESPSPR-SAPSSQ 373
Query: 2590 NHHGSAQEQLRDGSRHPRSHQEDRAGHGHSADSSRQSGTRHTQTSSGGQAASSHEQARSS 2649
G A G+ R + R SA + R+ G R + + ++ S +ARSS
Sbjct: 374 GRGGRA----AGGAGRRRRRRRRRRRSRSSASAPRRRGRRRPRPAPPRGSSRSLSRARSS 429
Query: 2650 AGERHGSHHQQSADSSRHSGIGHGQASSAVRDSGHRGYSGSQASDNEGHSEDSDTQSVSA 2709
+ G S GHG ++ R S + H + S+
Sbjct: 430 SDSGSG-RGAPGPGPEPGSERGHGGHGKRAKERPPRARPASTSPSPGAHGRRGGPEGKSS 488
Query: 2710 HGQAGSHQQSHQES-----ARGRSGETSGHSGSF----LYQVSTHEQSES-SHGWTGPST 2759
G H +S S +R RS E HS S +S + E + +T
Sbjct: 489 SRSPGPHPRSWSSSRSPSKSRSRSAEKRPHSPSRSPSPKKPLSRDKDGEGRARHSEAEAT 548
Query: 2760 RGRQGSR-----HEQAQDSSRH-------SASQDGQDTIRGHPGSSRGGRQGYHHEHSVD 2807
R R+ SR ++ +DS SA + R P SS + S
Sbjct: 549 RARRRSRSYSPIRKRRRDSPSFMEPRRITSARKRPIPYYRPSPSSSSSCLSSDYSTRSHS 608
Query: 2808 SSGHSGSHHSHTTSQGRSDASRGQSGSRSASRTTRNEEQSGDG 2850
S G H +S+ SR +S SR+ S + + S G
Sbjct: 609 RSPSPGHSHGSYSSRSHGTRSRTRSPSRTPSPSYHSRSSSESG 651
Score = 57.4 bits (137), Expect = 3e-07
Identities = 122/556 (21%), Positives = 181/556 (32%), Gaps = 81/556 (14%)
Query: 1979 TRHTESSSRGQAASSHEQARSSAGERHGSHHQLQSADSSRHSGIGHGQASSAVRDSGHRG 2038
T+H SSS ++ + R +L+S S S + S + R
Sbjct: 156 TKHWSSSSASPPPKKKKK-KKGGHRRSRKKRRLESECSCGSSSPLRKKKKSVKKHRRDRS 214
Query: 2039 YSGSQASDSEGHSEDSDTQSVSAQGKAGPHQQSH-KESARGQSGESSGRSGSFLYQVSTH 2097
SGS+ + + K PH +S + S R SG S+H
Sbjct: 215 DSGSRRKRRHRSRSSKCKRKEKNKEKKRPHTESPGRRSHRHSSG-------------SSH 261
Query: 2098 EQSESTHGQSAPSTGGRQGSHYDQAQDSSRHSASQEGQDTIRGHPGPSRGGRQGSHQEQS 2157
S S+H + S H D+ + + +S + G G R G ++S
Sbjct: 262 SPSLSSHYSDSRSPSRLSPKHRDEGRKTGSQRSSGSRSPSPSGGSGWGSPQRNGGSGQRS 321
Query: 2158 VDRSGHSGSHH------SHTTSQGRSDASRG-----QSGSRSASRKTYDKEQSGDGSRHS 2206
G GS H S + + R A+ G S S ++ Q G
Sbjct: 322 GAHGGRPGSAHSPPDKPSSPSPRVRDKAAAAAPTPPARGKESPSPRSAPSSQGRGGRAAG 381
Query: 2207 GSHHHEASSWADSSRHSLVGQGQSSG---PRTSRPRGSSVSQDSDSEGHSEDSERRSGSA 2263
G+ S + G PR + PRGSS S S RS S
Sbjct: 382 GAGRRRRRRRRRRRSRSSASAPRRRGRRRPRPAPPRGSSRSL----------SRARSSSD 431
Query: 2264 SRNHHGSAQEQSRDGSRHPRSHH----EDRAGHGHSAESSRQSGTHHAENSSGGQAASSH 2319
S + G+ GS H ++R A +S G H G+++S
Sbjct: 432 SGSGRGAPGPGPEPGSERGHGGHGKRAKERPPRARPASTSPSPGAHGRRGGPEGKSSS-- 489
Query: 2320 EQARSSAGERHGSHHQQSADSSRHSGIGHGQASSAVRDSGHRGSSGSQA-SDSEGHSEDS 2378
R H +S SSR + S R + R S S++ S + S D
Sbjct: 490 ---------RSPGPHPRSWSSSR------SPSKSRSRSAEKRPHSPSRSPSPKKPLSRDK 534
Query: 2379 DTQSVSAHGQAGPHQQSHQESTRGRSAGRSGRSGSFLYQVSTHEQSESAHGRTGTSTGGR 2438
D + + H +A E+TR R RS + + R TS R
Sbjct: 535 DGEGRARHSEA--------EATRARRRSRSYSP----IRKRRRDSPSFMEPRRITSARKR 582
Query: 2439 QGSHHKQARDSSRHSTSQEGQDTIHGHPGSSSGGRQGSHYEQLVDRSGHSGSHHSHTTSQ 2498
+++ + SS S + H S G GS+ S S S T S
Sbjct: 583 PIPYYRPSPSSSSSCLSSDYSTRSHSR-SPSPGHSHGSY-------SSRSHGTRSRTRSP 634
Query: 2499 GRSDASHGHSGSRSAS 2514
R+ + HS S S S
Sbjct: 635 SRTPSPSYHSRSSSES 650
Score = 45.8 bits (107), Expect = 9e-04
Identities = 77/330 (23%), Positives = 115/330 (34%), Gaps = 37/330 (11%)
Query: 3655 GHRGSSGSQASDSEGHSEDSDTQSVSAHGQAGPHQQSHQESTRGRSAGRSGRSGSFLYQV 3714
GHRG S S + + G H++S ++ R S G S +
Sbjct: 150 GHRGYRTKHWSSSSASPPPKKKKK-----KKGGHRRSRKKR-RLESECSCGSSSP----L 199
Query: 3715 STHEQSESAHGRAGPSTGGRQGSRHEQARDSSRHSASQEGQDTIRGHPGSRRGGRQGSYH 3774
++S H R +G R+ RH SS+ ++ ++ R H S GR+ H
Sbjct: 200 RKKKKSVKKHRRDRSDSGSRRKRRHRSR--SSKCKRKEKNKEKKRPHTES--PGRRSHRH 255
Query: 3775 EQSVDRSGHSGSHHSHTTSQGRSDASHGQSGSRSASRE---TRNEEQSGDGSRHSGSRHH 3831
S SH+S + S R H G ++ S+ +R+ SG GS + +
Sbjct: 256 SSGSSHSPSLSSHYSDSRSPSRLSPKHRDEGRKTGSQRSSGSRSPSPSG-GSGWGSPQRN 314
Query: 3832 EASTQADSSRHSQSGQGESAGSRRSRRQGSSVSQDSDSEAYPEDSERRSESASRNHHGSS 3891
S Q + + G S + S S +D + A P R ES S SS
Sbjct: 315 GGSGQRSGAHGGRPGSAHSPPDKPS--SPSPRVRDKAAAAAPTPPARGKESPSPRSAPSS 372
Query: 3892 REQSRDGSRHPGSSHRDTASHVQSSPVQSDSS----------TAKEHGHFSSLSQDSAYH 3941
Q R G G+ R + S S+ A G SLS+ +
Sbjct: 373 --QGRGGRAAGGAGRRRRRRRRRRRSRSSASAPRRRGRRRPRPAPPRGSSRSLSRARSSS 430
Query: 3942 SGIQSRGSPHSSSSYHYQSEGTERQKGQSG 3971
RG+P G+ER G G
Sbjct: 431 DSGSGRGAPGPG-----PEPGSERGHGGHG 455
>gi|28559039 mediator complex subunit 1 [Homo sapiens]
Length = 1581
Score = 85.9 bits (211), Expect = 7e-16
Identities = 151/703 (21%), Positives = 242/703 (34%), Gaps = 100/703 (14%)
Query: 3291 HEQARSSPGERHGSRHQQSADSSRHSGIPRGQASSAVRDSRHWGSSGSQASDSEGHSEES 3350
+ Q++S GE + QS D+ G QA + + G +G ++
Sbjct: 871 NSQSQSGFGEEYFDESSQSGDNDDFKGFA-SQALNTLGVPMLGGDNGETKFKGNNQADTV 929
Query: 3351 DTQSVSGHGQAGPHQQSHQESARDRSGGRSGRSGSFLYQVSTHEQSESAHGRTRTSTGRR 3410
D +S G+A + D SG G L + G+ +T +
Sbjct: 930 DFSIISVAGKA--------LAPADLMEHHSGSQGPLL--------TTGDLGKEKTQKRVK 973
Query: 3411 QGSHHEQARDSSRHSASQEGQDTIRGH----PGSSRRGRQGSHYEQSVDRSGHSGSHHSH 3466
+G+ +S + S G D+ G P + + + + D G S SH S
Sbjct: 974 EGN------GTSNSTLSGPGLDSKPGKRSRTPSNDGKSKDKPPKRKKADTEGKSPSHSSS 1027
Query: 3467 --------TTSQGRSDASRGQSGS----------RSASRQTRNDEQSGDGSRHS-WSHHH 3507
+T +S S G+S + + + + G S HS ++
Sbjct: 1028 NRPFTPPTSTGGSKSPGSAGRSQTPPGVATPPIPKITIQIPKGTVMVGKPSSHSQYTSSG 1087
Query: 3508 EASTQADSSRHSQSGQGQSAGP-----RTSRNQGSSVSQDSDSQGHSEDSERWSGSASRN 3562
S+ S HS S S+ ++S+++GSS S+ S S S+ S S S
Sbjct: 1088 SVSSSGSKSHHSHSSSSSSSASTSGKMKSSKSEGSSSSKLSSSMYSSQGS-----SGSSQ 1142
Query: 3563 HRGSAQEQSRDGSRHPTSHHEDRAGHGHSAESSRQSGTHHAENSSGGQAASSHEQARSSA 3622
+ S+Q + GS T H + S + Q N S + S +R
Sbjct: 1143 SKNSSQSGGKPGSSPITKH--GLSSGSSSTKMKPQGKPSSLMNPSLSKPNISPSHSRPPG 1200
Query: 3623 GERH---------GSHHQQSADSSRHSGIGHGQASSAVRDSGHRGSSG-------SQASD 3666
G G+ A S SG G S SG + SSG SQ +
Sbjct: 1201 GSDKLASPMKPVPGTPPSSKAKSPISSGSGGSHMSGTSSSSGMKSSSGLGSSGSLSQKTP 1260
Query: 3667 SEGHSEDSDTQSVSAHGQAGPHQQSHQESTRGRSAGR-------------------SGRS 3707
+S + + S S+ G + Q+ S++G+S R SG
Sbjct: 1261 PSSNSCTASSSSFSSSGSSMSSSQNQHGSSKGKSPSRNKKPSLTAVIDKLKHGVVTSGPG 1320
Query: 3708 GSFLYQ----VSTHEQSESAHGRAGPSTGGRQGSRHEQARDSSRHSASQEGQDTIRGHPG 3763
G VST+ S + S G QG R + +D S+ S S D+ +
Sbjct: 1321 GEDPLDGQMGVSTNSSSHPMSSKHNMSGGEFQGKREKSDKDKSKVSTSGSSVDSSKKTSE 1380
Query: 3764 SRRGGRQGSYHEQSVDRSGHSGSHHSHTTSQGRSDAS-HGQSGSRSASRETRNEEQSGDG 3822
S+ G G G S S + T Q ++S G ++S+ + SG
Sbjct: 1381 SKNVGSTGVAKIIISKHDGGSPSIKAKVTLQKPGESSGEGLRPQMASSKNYGSPLISGST 1440
Query: 3823 SRHS-GSRHHEAS-TQADSSRHSQSGQGESAGSRRSRRQGSSVSQDSDSEAYPEDSERRS 3880
+H GS H S + S+S G S + + SS Y + ++
Sbjct: 1441 PKHERGSPSHSKSPAYTPQNLDSESESGSSIAEKSYQNSPSSDDGIRPLPEYSTEKHKKH 1500
Query: 3881 ESASRNHHGSSREQSRDGSRHPGSSHRDTASHVQSSPVQSDSS 3923
+ + R++ RD R SH SP+ SD S
Sbjct: 1501 KKEKKKVKDKDRDRDRDKDRDKKKSHSIKPESWSKSPISSDQS 1543
Score = 80.5 bits (197), Expect = 3e-14
Identities = 133/601 (22%), Positives = 207/601 (34%), Gaps = 47/601 (7%)
Query: 1226 SGDGSRHSGSRHHEAASWADSSRHSQVGQEQSSGSRTSRHQGSSVSQDSDSERHSDDSER 1285
+GD + + + + +S S G + G R+ S+D +R D+E
Sbjct: 960 TGDLGKEKTQKRVKEGNGTSNSTLSGPGLDSKPGKRSRTPSNDGKSKDKPPKRKKADTEG 1019
Query: 1286 LSGSASRNHHGSSREQSRDGSRHPGFHQEDRASHGHSADSSRQ------SGTHHT-ESSS 1338
S S S ++ + S GS+ PG + G + + GT + SS
Sbjct: 1020 KSPSHSSSNRPFTPPTSTGGSKSPGSAGRSQTPPGVATPPIPKITIQIPKGTVMVGKPSS 1079
Query: 1339 HGQAVSSHEQARSSPGERHGSRHQQSADSSRHSGIGHRQASSAVRDSGHRGSSGSQVTNS 1398
H Q SS + SS G + H S+ SS S ++ S GSS S++++S
Sbjct: 1080 HSQYTSS--GSVSSSGSKSHHSHSSSSSSS-------ASTSGKMKSSKSEGSSSSKLSSS 1130
Query: 1399 EGHSEDSDTQSVSAH-GQAGPHQQSHKESARGQSGESSGRSRSFLYQVSSHEQSESTHGQ 1457
S+ S S S + Q+G S + G S SS + SS +
Sbjct: 1131 MYSSQGSSGSSQSKNSSQSGGKPGSSPITKHGLSSGSSSTKMKPQGKPSSLMNPSLSKPN 1190
Query: 1458 TAPS----TGGRQGSRHEQARNSSRHSASQDGQDTIRGHPGSSRGGRQGSYHEQSVDRSG 1513
+PS GG +S+ G GS G S +S G
Sbjct: 1191 ISPSHSRPPGGSDKLASPMKPVPGTPPSSKAKSPISSGSGGSHMSGTSSSSGMKSSSGLG 1250
Query: 1514 HSGYHHSHTTPQGRSDASHGQSGPRSASRQTRNEEQSGDGSRHSGSRHHEPSTRA--GSS 1571
SG T P S + S S S + ++ Q G S SR+ +PS A
Sbjct: 1251 SSGSLSQKTPPSSNSCTASSSSFSSSGSSMSSSQNQHGSSKGKSPSRNKKPSLTAVIDKL 1310
Query: 1572 RHSQVGQGESAGSKTSRRQGSSVSQDRDSEGHSEDSERRSESASRNHYGSAREQSRHGSR 1631
+H V G + G S +S H S+ + S + RE+S
Sbjct: 1311 KHGVVTSGPGGEDPLDGQMGVST----NSSSHPMSSK---HNMSGGEFQGKREKSDKDKS 1363
Query: 1632 NPRSHQEDRASHGHSAESSRQSGTRHAE----TSSGGQAASSQEQARSSPGERHGSRHQQ 1687
+ S ++ES T A+ GG + + PGE G +
Sbjct: 1364 KVSTSGSSVDSSKKTSESKNVGSTGVAKIIISKHDGGSPSIKAKVTLQKPGESSGEGLRP 1423
Query: 1688 SADSSTDSGTGRRQDSSVVGDSGNRGSSGSQASDSEGHSEESDTQSVSAHGQAGPHQQSH 1747
SS + G+ S+ + G+ S S A + ES++ S A ++S+
Sbjct: 1424 QMASSKNYGSPLISGSTPKHERGSPSHSKSPAYTPQNLDSESESGSSIA-------EKSY 1476
Query: 1748 QESTRGQSGERSGRSGSFLYQVSTHEQSESAHGRTGPSTGGRQRSRHEQARDSSRHSASQ 1807
Q S G R L + ST + + + R R R + HS
Sbjct: 1477 QNSPSSDDGIRP------LPEYSTEKHKKHKKEKKKVKDKDRDRDRDKDRDKKKSHSIKP 1530
Query: 1808 E 1808
E
Sbjct: 1531 E 1531
Score = 79.3 bits (194), Expect = 7e-14
Identities = 164/787 (20%), Positives = 283/787 (35%), Gaps = 88/787 (11%)
Query: 623 QDSDSQGHSE----DSERWSGSASRNHHGSAQEQSRDGSRHPRS---------------- 662
+DS S GHS+ DS+ + + + N + + D + P S
Sbjct: 808 RDSSSSGHSQSTLFDSDVFQTNNNENPYTDPADLIADAAGSPSSDSPTNHFFHDGVDFNP 867
Query: 663 ---HHEDRAGHGHSA-DSSRKSGTRHTQNSSSGQAASSH--EQARSSAGE-RHGSRHQLQ 715
+ + ++G G D S +SG + QA ++ GE + +Q
Sbjct: 868 DLLNSQSQSGFGEEYFDESSQSGDNDDFKGFASQALNTLGVPMLGGDNGETKFKGNNQAD 927
Query: 716 SADSSRHSGTG-----------HGQASSAVRDSGHRGSSGSQATDSEGHSEDSDTQSVSG 764
+ D S S G H + + +G G +Q EG+ + T S G
Sbjct: 928 TVDFSIISVAGKALAPADLMEHHSGSQGPLLTTGDLGKEKTQKRVKEGNGTSNSTLSGPG 987
Query: 765 -HGQAGHHQQSHQESARDRSGERSRRSGSFLYQVSTHKQSESSHGWTGPSTGVRQGSHHE 823
+ G ++ + + R+ + +H S S+ +T P++ S
Sbjct: 988 LDSKPGKRSRTPSNDGKSKDKPPKRKKADTEGKSPSH--SSSNRPFTPPTSTGGSKSPGS 1045
Query: 824 QARDNSRHSASQDG--QDTIRGHPGSSRRGRQGSHHEQ----SVDRSGHSGSHHSHTTSQ 877
R + + + TI+ G+ G+ SH + SV SG S SHHSH++S
Sbjct: 1046 AGRSQTPPGVATPPIPKITIQIPKGTVMVGKPSSHSQYTSSGSVSSSG-SKSHHSHSSS- 1103
Query: 878 GRSDASRGQSGSRSASRTTRNEEQSRDGSRHSGSRHHEASSHADISRHSQAGQGQSEGSR 937
S +S SG +S++ + S +S + SS + S++S G+ S
Sbjct: 1104 --SSSSASTSGKMKSSKSEGSSSSKLSSSMYSS----QGSSGSSQSKNSSQSGGKPGSSP 1157
Query: 938 TSRRQGSSVSQDSDSEGHSEDSERWSGSASRNHRGSAQEQSRHGSRHPRSHHEDRAGHGH 997
++ SS S + + + S + S S+ + + + GS S + G
Sbjct: 1158 ITKHGLSSGSSSTKMKPQGKPSSLMNPSLSKPNISPSHSRPPGGSDKLASPMKPVPGTPP 1217
Query: 998 SADSSRQSGTPHAETSSGGQAASSHEQARSSPGERHGSRHQQSADSSRHSGIPRRQASSA 1057
S+ + + + G ++SS ++ S G GS Q++ SS +S
Sbjct: 1218 SSKAKSPISSGSGGSHMSGTSSSSGMKSSSGLGS-SGSLSQKTPPSS----------NSC 1266
Query: 1058 VRDSGHWGSSGSQASDSEGHSEESDTQSVSGHGQ---DGPHQQSHQESARDWSGGRSGRS 1114
S + SSGS S S+ S +S S + + + GG
Sbjct: 1267 TASSSSFSSSGSSMSSSQNQHGSSKGKSPSRNKKPSLTAVIDKLKHGVVTSGPGGEDPLD 1326
Query: 1115 GSFIYQVSTHEQSESAHGRTRTSTGRRQGSHHEQARDSSRHSASQEGQDTIRAHPGSRRG 1174
G VST+ S + S G QG + +D S+ S S D+ + S+
Sbjct: 1327 GQM--GVSTNSSSHPMSSKHNMSGGEFQGKREKSDKDKSKVSTSGSSVDSSKKTSESKNV 1384
Query: 1175 GRQGSHHEQSVDRSGHSGSHHSHTTSQGRSDASHGQSGSRSASRQTRKDKQSGDGSRHSG 1234
G G G S S + T Q G+S Q K G
Sbjct: 1385 GSTGVAKIIISKHDGGSPSIKAKVTLQ-----KPGESSGEGLRPQMASSKNYGSPLISGS 1439
Query: 1235 SRHHEAASWADSSRHSQVGQEQSSGSRTSRHQGSSVSQDS-DSERHSDDSERLSGSASRN 1293
+ HE S + S + Q S S + GSS+++ S + SDD R S
Sbjct: 1440 TPKHERGSPSHSKSPAYTPQNLDSESES----GSSIAEKSYQNSPSSDDGIRPLPEYSTE 1495
Query: 1294 HHGSSREQ-----SRDGSRHPGFHQEDRASHGHSADSSRQS--GTHHTESSSHGQAVSSH 1346
H +++ +D R ++ + SH +S +S + + S + +S+
Sbjct: 1496 KHKKHKKEKKKVKDKDRDRDRDKDRDKKKSHSIKPESWSKSPISSDQSLSMTSNTILSAD 1555
Query: 1347 EQARSSP 1353
+R SP
Sbjct: 1556 RPSRLSP 1562
Score = 77.4 bits (189), Expect = 3e-13
Identities = 135/603 (22%), Positives = 218/603 (36%), Gaps = 47/603 (7%)
Query: 577 SGDGTRHSGSRHHEASSQADSSRHSQVGQGQSSGPRTSRNQGSSVSQDSDSQGHSEDSER 636
+GD + + + + +S S G G R+ S+D + D+E
Sbjct: 960 TGDLGKEKTQKRVKEGNGTSNSTLSGPGLDSKPGKRSRTPSNDGKSKDKPPKRKKADTEG 1019
Query: 637 WSGSASRNHHGSAQEQSRDGSRHPRSHHEDRAGHGHSADSSRKSGTRHTQNSSSGQAASS 696
S S S ++ S GS+ P S + G + K + + + SS
Sbjct: 1020 KSPSHSSSNRPFTPPTSTGGSKSPGSAGRSQTPPGVATPPIPKITIQIPKGTVMVGKPSS 1079
Query: 697 HEQARSSAG-ERHGSR-HQLQSADSSRHSGTGHGQASSAVRDSGHRGSSGSQATDSEGHS 754
H Q SS GS+ H S+ SS + T S ++ S GSS S+ + S S
Sbjct: 1080 HSQYTSSGSVSSSGSKSHHSHSSSSSSSAST-----SGKMKSSKSEGSSSSKLSSSMYSS 1134
Query: 755 EDSDTQSVSGHGQAGHHQQSHQESARDRSGERSRRSGSFLYQVSTHKQSESSHGWTGPST 814
+ S SG Q+ + QS + + SGS ++ + S PS
Sbjct: 1135 QGS-----SGSSQSKNSSQSGGKPGSSPITKHGLSSGSSSTKMKPQGKPSS---LMNPSL 1186
Query: 815 GVRQGSHHEQARDNSRHSASQDGQDTIRGHPGSSRRGRQGSHHEQSVDRSGHSGSHHSHT 874
+ + HS G D + P G S +S SG GSH S T
Sbjct: 1187 --------SKPNISPSHSRPPGGSDKL-ASPMKPVPGTPPSSKAKSPISSGSGGSHMSGT 1237
Query: 875 TSQGRSDASRGQSGSRSASRTTRNEEQSRDGSRHSGSRHHEASSHADISRHSQAGQGQSE 934
+S +S G S S S+ T S S S S SS + +S SQ G S+
Sbjct: 1238 SSSSGMKSSSGLGSSGSLSQKTPPSSNSCTASSSSFS-----SSGSSMS-SSQNQHGSSK 1291
Query: 935 GSRTSRRQGSSVSQDSDSEGHSEDSERWSGSASRNHRGSAQEQSRHGSRHPRSHHEDRAG 994
G SR + S++ D H + SG + S + S HP S + +G
Sbjct: 1292 GKSPSRNKKPSLTAVIDKLKHGVVT---SGPGGEDPLDGQMGVSTNSSSHPMSSKHNMSG 1348
Query: 995 HGHSADSSRQSGTPHAETSSGGQAASSHEQARSSPGERHGSRHQQSADSSRH-SGIPRRQ 1053
G +S ++ S+ G + S + ++S + GS S+H G P +
Sbjct: 1349 -GEFQGKREKSDKDKSKVSTSGSSVDSSK--KTSESKNVGSTGVAKIIISKHDGGSPSIK 1405
Query: 1054 ASSAVRDSGHWGSSG--SQASDSEGHSEESDTQSVSGHGQDGP-HQQSHQESARDWSGGR 1110
A ++ G G Q + S+ + + S H + P H +S + ++
Sbjct: 1406 AKVTLQKPGESSGEGLRPQMASSKNYGSPLISGSTPKHERGSPSHSKSPAYTPQNLDS-- 1463
Query: 1111 SGRSGSFIYQVSTHEQSESAHG-----RTRTSTGRRQGSHHEQARDSSRHSASQEGQDTI 1165
SGS I + S S G T ++ ++ +D R + +D
Sbjct: 1464 ESESGSSIAEKSYQNSPSSDDGIRPLPEYSTEKHKKHKKEKKKVKDKDRDRDRDKDRDKK 1523
Query: 1166 RAH 1168
++H
Sbjct: 1524 KSH 1526
Score = 67.0 bits (162), Expect = 4e-10
Identities = 158/689 (22%), Positives = 247/689 (35%), Gaps = 117/689 (16%)
Query: 265 GKSSSQVNRSRHENTSQVPLQESRTRKRRGSRVSQDRDSEGHSEDSERHSGSASRNHHGS 324
GK+ + + H + SQ PL T G +Q R EG+ + SG + G
Sbjct: 938 GKALAPADLMEHHSGSQGPLL---TTGDLGKEKTQKRVKEGNGTSNSTLSGPGLDSKPG- 993
Query: 325 AWEQSRDGSRHPRSHDEDRASHGHSADSSRQSGTRHAETSSRGQTASSHEQARSSPGERH 384
++SR S +S D + + A+T + + SS + + P
Sbjct: 994 --KRSRTPSNDGKSKD-------------KPPKRKKADTEGKSPSHSSSNRPFTPPTSTG 1038
Query: 385 GSGHQQSADSSRHSATGRGQASSAVSDRGHRGSSGS-QASDSEGHSENSDTQSVSGHGKA 443
GS +S S+ S T G A+ + + G+ HS+ + + SVS
Sbjct: 1039 GS---KSPGSAGRSQTPPGVATPPIPKITIQIPKGTVMVGKPSSHSQYTSSGSVSS---- 1091
Query: 444 GLRQQSHQESTRGRSGERSGRSGSSLYQVSTHEQPDSAHGRTGTSTGGRQGSHHEQARDS 503
SG +S S SS + ST G+ S + S
Sbjct: 1092 --------------SGSKSHHSHSS-------------SSSSSASTSGKMKSSKSEGSSS 1124
Query: 504 SRHS----ASQEGQDTIRGHPGSSRGGRQGSHHEQSVNRSG-HSGSHHSHTTSQGRSDAS 558
S+ S +SQ + + S GG+ GS + + G SGS + QG+ +
Sbjct: 1125 SKLSSSMYSSQGSSGSSQSKNSSQSGGKPGS---SPITKHGLSSGSSSTKMKPQGKPSSL 1181
Query: 559 HGQSGSRSASRQTRNEEQSGD-----------GTRHSGSRHHEASSQADSSRHSQVGQGQ 607
S S+ + + G GT S SS + S S G
Sbjct: 1182 MNPSLSKPNISPSHSRPPGGSDKLASPMKPVPGTPPSSKAKSPISSGSGGSHMS--GTSS 1239
Query: 608 SSGPRTSRNQGSSVS------QDSDSQGHSEDSERWSG---SASRNHHGSAQEQSRDGSR 658
SSG ++S GSS S S+S S S SG S+S+N HGS++ +S ++
Sbjct: 1240 SSGMKSSSGLGSSGSLSQKTPPSSNSCTASSSSFSSSGSSMSSSQNQHGSSKGKSPSRNK 1299
Query: 659 HPR--------SHHEDRAGHGHSADSSRKSGTRHTQNSSSGQAASSHEQARSSAGERHGS 710
P H +G G + G + NSSS +S H S GE G
Sbjct: 1300 KPSLTAVIDKLKHGVVTSGPGGEDPLDGQMGV--STNSSSHPMSSKHNM---SGGEFQGK 1354
Query: 711 RHQLQSADSSRHSGTGHG-QASSAVRDSGHRGSSGSQATDSEGHSEDSDTQSVSGHGQAG 769
R + D S+ S +G +S +S + GS+G H D + S+
Sbjct: 1355 REK-SDKDKSKVSTSGSSVDSSKKTSESKNVGSTGVAKIIISKH--DGGSPSIKAKVTLQ 1411
Query: 770 HHQQSHQESARDRSGERSRRSGSFLYQVST--HKQSESSHGWTGPSTGVRQGSHHEQARD 827
+S E R + S+ GS L ST H++ SH + T S E
Sbjct: 1412 KPGESSGEGLRPQMAS-SKNYGSPLISGSTPKHERGSPSHSKSPAYTPQNLDSESESGSS 1470
Query: 828 NSRHS-----ASQDG-----QDTIRGHPGSSRRGRQGSHHEQSVDRSGHSGSHHSHT--- 874
+ S +S DG + + H + ++ ++ DR SH+
Sbjct: 1471 IAEKSYQNSPSSDDGIRPLPEYSTEKHKKHKKEKKKVKDKDRDRDRDKDRDKKKSHSIKP 1530
Query: 875 TSQGRSDASRGQSGSRSASRTTRNEEQSR 903
S +S S QS S +++ + SR
Sbjct: 1531 ESWSKSPISSDQSLSMTSNTILSADRPSR 1559
Score = 66.2 bits (160), Expect = 6e-10
Identities = 161/801 (20%), Positives = 263/801 (32%), Gaps = 166/801 (20%)
Query: 2893 QDSDSEGHSE----DSERWSGSASRNHHGSAQEQLRDGSRHPRSHQEDRAGHGHSADSSR 2948
+DS S GHS+ DS+ + + + N + + + D + P S D +
Sbjct: 808 RDSSSSGHSQSTLFDSDVFQTNNNENPYTDPADLIADAAGSPSSDSPTNHFFHDGVDFNP 867
Query: 2949 QSGTRHTQTSSGGQAASSHEQARSSAGERHGSHHQQSADSSRHSGIGHGQASSAVR---- 3004
+ Q++S GE + QS D+ G QA + +
Sbjct: 868 DL---------------LNSQSQSGFGEEYFDESSQSGDNDDFKGFA-SQALNTLGVPML 911
Query: 3005 --DSGHRGYSGSQASDNEGHSEDSDTQSVSAHGQAGSHQQSHQESARGRSGETSGHSGSF 3062
D+G + G+ N+ + D SV+ A + H ++G T+G G
Sbjct: 912 GGDNGETKFKGN----NQADTVDFSIISVAGKALAPADLMEHHSGSQGPL-LTTGDLGKE 966
Query: 3063 LYQVSTHEQSESSHGW-TGPSTRGRQGSRHEQAQDSSRHSASQYGQDTIRGHPGSSRGGR 3121
Q E + +S+ +GP + G R + + P +
Sbjct: 967 KTQKRVKEGNGTSNSTLSGPGLDSKPGKRSRTPSNDGKSKDKP---------PKRKKADT 1017
Query: 3122 QGYHHEHSVDSSGHSGSHHSHT--TSQGRSDASRGQSGSRSASRTTRNEEQSGDSSRHSV 3179
+G S HS S+ T TS G GS+S R++ G V
Sbjct: 1018 EG-------KSPSHSSSNRPFTPPTSTG---------GSKSPGSAGRSQTPPG------V 1055
Query: 3180 SRHHEASTHADISRHSQAVQGQSEGSRRSRRQGSSVSQDSDSEGHSEDSERWSGSASRNH 3239
+ I + + V S S+ + SVS HS S S S+S +
Sbjct: 1056 ATPPIPKITIQIPKGTVMVGKPSSHSQYT--SSGSVSSSGSKSHHSHSS---SSSSSAST 1110
Query: 3240 RGSVQEQSRHGSRHPRSHHEDRAGHGHSADRSRQSGTRHAETSSGGQAASSHEQARSSPG 3299
G ++ GS + S ++ SSG + + Q+ PG
Sbjct: 1111 SGKMKSSKSEGS----------------SSSKLSSSMYSSQGSSGSSQSKNSSQSGGKPG 1154
Query: 3300 ERHGSRHQQSADSSRHSGIPRGQASSAVR-----------DSRHWGSSGSQASDSE---G 3345
++H S+ SS P+G+ SS + SR G S AS + G
Sbjct: 1155 SSPITKHGLSSGSSSTKMKPQGKPSSLMNPSLSKPNISPSHSRPPGGSDKLASPMKPVPG 1214
Query: 3346 HSEESDTQSVSGHGQAGPHQQSHQESARDRSGGRSGRSGSFLYQVSTHEQSESAHGRTRT 3405
S +S G G H S+ +S G SGS + S +A + +
Sbjct: 1215 TPPSSKAKSPISSGSGGSHMSGTSSSSGMKSSSGLGSSGSLSQKTPPSSNSCTASSSSFS 1274
Query: 3406 STGRRQGSHHEQARDSSRHSASQE----------------------GQDTIRG------- 3436
S+G S Q S S S+ G+D + G
Sbjct: 1275 SSGSSMSSSQNQHGSSKGKSPSRNKKPSLTAVIDKLKHGVVTSGPGGEDPLDGQMGVSTN 1334
Query: 3437 ---HPGSSRRGRQGSHYEQSVDRSGHSGSHHSHTTSQGRSDASRGQSGSRSASRQTRNDE 3493
HP SS+ G ++ ++S S S + S S +S + ++ +
Sbjct: 1335 SSSHPMSSKHNMSGGEFQGKREKSDKDKSKVSTSGSSVDSSKKTSESKNVGSTGVAKIII 1394
Query: 3494 QSGDGSRHSWSHHHEASTQADSSRHSQSGQGQSAGPRTSRNQGSSVSQDSDSQGHSEDSE 3553
DG S +S SG+G +S+N GS +
Sbjct: 1395 SKHDGGSPSIKAKVTLQKPGES-----SGEGLRPQMASSKNYGSPLI------------- 1436
Query: 3554 RWSGSASRNHRGSAQEQSRDGSRHPTSHHEDRAGHGHSAESSRQSGTHHAENSSGGQAAS 3613
SGS ++ RGS SH + A + +S +SG+ AE S +S
Sbjct: 1437 --SGSTPKHERGS------------PSHSKSPAYTPQNLDSESESGSSIAEKSYQNSPSS 1482
Query: 3614 SH--EQARSSAGERHGSHHQQ 3632
+ E+H H ++
Sbjct: 1483 DDGIRPLPEYSTEKHKKHKKE 1503
Score = 65.5 bits (158), Expect = 1e-09
Identities = 100/493 (20%), Positives = 169/493 (34%), Gaps = 44/493 (8%)
Query: 1209 GQSGSRSASRQTRKDKQSGDGSRHSGSRHHEAASWADSSRHSQVGQEQSSGSRTSRHQGS 1268
G+ S S + SG S HS S +++ S + SS +S S
Sbjct: 1075 GKPSSHSQYTSSGSVSSSGSKSHHSHSSSSSSSASTSGKMKSSKSEGSSSSKLSSSMYSS 1134
Query: 1269 SVSQDSDSERHSDDSERLSGSASRNHHGSSREQSRDGSRHPGFHQEDRASHGHSADSSRQ 1328
S S ++S S GS+ HG S G G +
Sbjct: 1135 QGSSGSSQSKNSSQSGGKPGSSPITKHGLS----------SGSSSTKMKPQGKPSSLMNP 1184
Query: 1329 SGTHHTESSSHGQAVSSHEQARSSPGERHGSRHQQSADSSRHSGIGHRQASSAVRDSGHR 1388
S + S SH + ++ S G+ A S SG G S SG +
Sbjct: 1185 SLSKPNISPSHSRPPGGSDKLASPMKPVPGTPPSSKAKSPISSGSGGSHMSGTSSSSGMK 1244
Query: 1389 GSSGSQVTNSEGHSEDSDTQSVSAHGQAGPHQQSHKESARGQSGESSGRSRSFLYQVS-S 1447
SSG + S + S +A + S S++ Q G S G+S S + S +
Sbjct: 1245 SSSGLGSSGSLSQKTPPSSNSCTASSSSFSSSGSSMSSSQNQHGSSKGKSPSRNKKPSLT 1304
Query: 1448 HEQSESTHGQTAPSTGGRQGSRHEQARNSSRHSASQDGQDTIRGHPGSSRGGRQGSYHEQ 1507
+ HG GG + +++ S + + G G +G R+ S ++
Sbjct: 1305 AVIDKLKHGVVTSGPGGEDPLDGQMGVSTNSSSHPMSSKHNMSG--GEFQGKREKSDKDK 1362
Query: 1508 SVDRSGHSGYHHSHTTPQGRSDAS----------HGQSGPRSASRQTRNE--EQSGDGSR 1555
S + S S T + ++ S H P ++ T + E SG+G R
Sbjct: 1363 SKVSTSGSSVDSSKKTSESKNVGSTGVAKIIISKHDGGSPSIKAKVTLQKPGESSGEGLR 1422
Query: 1556 ---HSGSRHHEPSTRAGSSRHSQVGQGESAGSKTSRRQGSSVSQDRDSEGHSEDS--ERR 1610
S + P + +H + GS + + + Q+ DSE S S E+
Sbjct: 1423 PQMASSKNYGSPLISGSTPKHER-------GSPSHSKSPAYTPQNLDSESESGSSIAEKS 1475
Query: 1611 SESASRNHYG-------SAREQSRHGSRNPRSHQEDRASHGHSAESSRQSGTRHAETSSG 1663
+++ + G S + +H + +DR ++S + E+ S
Sbjct: 1476 YQNSPSSDDGIRPLPEYSTEKHKKHKKEKKKVKDKDRDRDRDKDRDKKKSHSIKPESWSK 1535
Query: 1664 GQAASSQEQARSS 1676
+S Q + +S
Sbjct: 1536 SPISSDQSLSMTS 1548
Score = 64.7 bits (156), Expect = 2e-09
Identities = 139/663 (20%), Positives = 219/663 (33%), Gaps = 96/663 (14%)
Query: 1629 GSRNPRSHQEDRASHGHSAESSRQSGTRHAETSSGGQAASSQEQARSSPGERHGSRHQQS 1688
GS+ P D +GT ++ S G S PG+R SR +
Sbjct: 952 GSQGPLLTTGDLGKEKTQKRVKEGNGTSNSTLSGPG--------LDSKPGKR--SRTPSN 1001
Query: 1689 ADSSTDSGTGRRQDSSVVGDSGNRGSSGSQASDSEGHSEESDTQSVSAHGQAGPHQQSHQ 1748
S D R++ + G S S +S + + + T + G AG Q
Sbjct: 1002 DGKSKDKPPKRKK-------ADTEGKSPSHSSSNRPFTPPTSTGGSKSPGSAGRSQTPPG 1054
Query: 1749 EST------------------RGQSGERSGRSGSFLYQVSTHEQSESAHGRTGPSTGGRQ 1790
+T + S + SGS S S S+ + ST G+
Sbjct: 1055 VATPPIPKITIQIPKGTVMVGKPSSHSQYTSSGSVSSSGSKSHHSHSSSSSSSASTSGKM 1114
Query: 1791 RSRHEQARDSSRHSASQEGQDTIRGHPGSSRGGRQGSHYEQSVDSSGHSGSH--HSHTTS 1848
+S + SS+ S+S SS+G S + S S G GS H S
Sbjct: 1115 KSSKSEGSSSSKLSSSMY----------SSQGSSGSSQSKNSSQSGGKPGSSPITKHGLS 1164
Query: 1849 QERSDVSRGQSGSRSVSRQTRNEKQSGDGSRHSGSRHHEASSRADSSRHSQVGQGQSSGP 1908
S G S N S S SR S + S G SS
Sbjct: 1165 SGSSSTKMKPQGKPS---SLMNPSLSKPNISPSHSRPPGGSDKLASPMKPVPGTPPSSKA 1221
Query: 1909 RTSRNQGSSVSQDSDSQGHSEDSERWSGSASRNHLGSAWEQSRDGSRHPGSHHEDRAGHG 1968
++ + GS S H + SG S + LGS+ S+ P S+ +
Sbjct: 1222 KSPISSGSGGS-------HMSGTSSSSGMKSSSGLGSSGSLSQ--KTPPSSNSCTASSSS 1272
Query: 1969 HSADSSRQSGTRHTESSSRGQAASSHEQARSSA---GERHGSHHQLQSADSSRHSGIGHG 2025
S+ S S +++ SS+G++ S +++ +A +HG + +G
Sbjct: 1273 FSSSGSSMSSSQNQHGSSKGKSPSRNKKPSLTAVIDKLKHGVVTSGPGGEDPLDGQMGVS 1332
Query: 2026 QASSAVRDSGHRGYSGSQASDSEGHSEDSDTQSVSAQGKAGPHQQSHKESAR-GQSG--- 2081
SS+ S SG + S D D VS G + + ES G +G
Sbjct: 1333 TNSSSHPMSSKHNMSGGEFQGKREKS-DKDKSKVSTSGSSVDSSKKTSESKNVGSTGVAK 1391
Query: 2082 ----ESSGRSGSFLYQVSTHEQSESTHGQSAPSTGGRQGSHYDQAQDSSRHSASQEGQDT 2137
+ G S S +V+ + ES+ P Q S + + T
Sbjct: 1392 IIISKHDGGSPSIKAKVTLQKPGESSGEGLRP-----------QMASSKNYGSPLISGST 1440
Query: 2138 IRGHPGPSRGGRQGSHQEQSVDRSGHSGSHHSHTTSQGRSDASRG-----------QSGS 2186
+ G + ++ Q++D SGS + + Q + G
Sbjct: 1441 PKHERGSPSHSKSPAYTPQNLDSESESGSSIAEKSYQNSPSSDDGIRPLPEYSTEKHKKH 1500
Query: 2187 RSASRKTYDKEQSGDGSR---HSGSHHHEASSWADSSRHSLVGQGQSSGPRTSRPRGSSV 2243
+ +K DK++ D + SH + SW+ S S +S S R S +
Sbjct: 1501 KKEKKKVKDKDRDRDRDKDRDKKKSHSIKPESWSKSPISSDQSLSMTSNTILSADRPSRL 1560
Query: 2244 SQD 2246
S D
Sbjct: 1561 SPD 1563
Score = 63.5 bits (153), Expect = 4e-09
Identities = 128/597 (21%), Positives = 209/597 (35%), Gaps = 85/597 (14%)
Query: 224 TQKWIQSGHIATYYTIQDEAYDTTDSLLEENKIYERSR--SSDGKSSSQV-NRSRHENTS 280
TQK ++ G+ + T+ D+ K +RSR S+DGKS + R + +
Sbjct: 968 TQKRVKEGNGTSNSTLSGPGLDS--------KPGKRSRTPSNDGKSKDKPPKRKKADTEG 1019
Query: 281 QVPLQESRTRKRRGSRVSQDRDSEGHSEDSERHSGSA----------------------S 318
+ P S R + S G + S+ G A S
Sbjct: 1020 KSPSHSSSNRPFTPPTSTGGSKSPGSAGRSQTPPGVATPPIPKITIQIPKGTVMVGKPSS 1079
Query: 319 RNHHGSAWEQSRDGSRHPRSHDEDRASHGHSADSSRQSGTRHAETSSRGQTASSHEQARS 378
+ + S+ S GS+ SH H HS+ SS + T SS+ + +SS + + S
Sbjct: 1080 HSQYTSSGSVSSSGSK---SH------HSHSSSSSSSASTSGKMKSSKSEGSSSSKLSSS 1130
Query: 379 SPGERHGSGHQQSADSSRHSATGRGQASSAVSDRGHRGSSGSQASDSEGHSENSDTQSVS 438
+ SG QS +SS+ +G SS ++ G S S +G + S+S
Sbjct: 1131 MYSSQGSSGSSQSKNSSQ---SGGKPGSSPITKHGLSSGSSSTKMKPQGKPSSLMNPSLS 1187
Query: 439 -------------GHGKAGLRQQ---SHQESTRGRSGERSGRSGSSLYQVSTHE--QPDS 480
G K + S++ +S SG GS + S+ + S
Sbjct: 1188 KPNISPSHSRPPGGSDKLASPMKPVPGTPPSSKAKSPISSGSGGSHMSGTSSSSGMKSSS 1247
Query: 481 AHGRTGTSTGGRQGSHHEQARDSSRHSASQEGQDTIRGHPGSSRGGRQGSHHEQSVNRSG 540
G +G+ + S + SS S+S + + GSS+G + + S+
Sbjct: 1248 GLGSSGSLSQKTPPSSNSCTASSSSFSSSGSSMSSSQNQHGSSKGKSPSRNKKPSLTAVI 1307
Query: 541 HSGSHHSHTTSQGRSDASHGQSG-SRSASRQTRNEEQSGDGTRHSGSRHHEASSQADSSR 599
H T+ G D GQ G S ++S + + + G G R S D S+
Sbjct: 1308 DKLKHGVVTSGPGGEDPLDGQMGVSTNSSSHPMSSKHNMSGGEFQGKRE---KSDKDKSK 1364
Query: 600 HSQVGQGQSSGPRT--SRNQGSSVSQDSDSQGHSEDSERWSGSASRNHHGSAQEQSRDGS 657
S G S +T S+N GS+ H S + G E S +G
Sbjct: 1365 VSTSGSSVDSSKKTSESKNVGSTGVAKIIISKHDGGSPSIKAKVTLQKPG---ESSGEGL 1421
Query: 658 RHPRSHHEDRAG---------HGHSADSSRKSGTRHTQN--SSSGQAASSHEQARSSAGE 706
R + ++ H + S KS QN S S +S E++ ++
Sbjct: 1422 RPQMASSKNYGSPLISGSTPKHERGSPSHSKSPAYTPQNLDSESESGSSIAEKSYQNSPS 1481
Query: 707 RHGSRHQLQSADSSRHSGTGHGQASSAVRDSGHRGSSGSQATDSEGHSEDSDTQSVS 763
L + +H H + V+D + HS ++ S S
Sbjct: 1482 SDDGIRPLPEYSTEKHK--KHKKEKKKVKDKDRDRDRDKDRDKKKSHSIKPESWSKS 1536
Score = 62.0 bits (149), Expect = 1e-08
Identities = 140/672 (20%), Positives = 217/672 (32%), Gaps = 76/672 (11%)
Query: 1994 HEQARSSAGERHGSHHQLQSADSSRHSGIGHGQASSAVRDSGHRGYSGSQASDSEGHSED 2053
+ Q++S GE + QS D+ G QA + + G +G ++
Sbjct: 871 NSQSQSGFGEEYFDESS-QSGDNDDFKGFA-SQALNTLGVPMLGGDNGETKFKGNNQADT 928
Query: 2054 SDTQSVSAQGKA--------------GPHQQSH---KESARGQSGESSGRSGSFLYQVST 2096
D +S GKA GP + KE + + E +G S S L
Sbjct: 929 VDFSIISVAGKALAPADLMEHHSGSQGPLLTTGDLGKEKTQKRVKEGNGTSNSTLSGPGL 988
Query: 2097 HEQSESTHGQSAPSTGGRQGSHYDQAQDSSRHSASQEGQDTIRGHPGPSRGGRQGSHQEQ 2156
S+ PS G+ + + + S + R P+ G GS
Sbjct: 989 --DSKPGKRSRTPSNDGKSKDKPPKRKKADTEGKSPSHSSSNRPFTPPTSTG--GSKSPG 1044
Query: 2157 SVDRS----GHSGSHHSHTTSQ-GRSDASRGQSGSRSASRKTYDKEQSGDGSRHSGSHHH 2211
S RS G + T Q + G+ S S + SG S HS S
Sbjct: 1045 SAGRSQTPPGVATPPIPKITIQIPKGTVMVGKPSSHSQYTSSGSVSSSGSKSHHSHSSSS 1104
Query: 2212 EASSWADSSRHSLVGQGQSSGPRTSRPRGSSVSQDSDSEGHSEDSERRSGSASRNHHGSA 2271
+S+ S +G SS +S S S S +S S + GS+ HG +
Sbjct: 1105 SSSASTSGKMKSSKSEGSSSSKLSSSMYSSQGSSGSSQSKNSSQSGGKPGSSPITKHGLS 1164
Query: 2272 QEQSRDGSRHPRSHHEDRAGHGHSAESSRQSGTHHAENSSGGQAASSHEQARSSAGERHG 2331
GS + + + + S+ + + GG ++ S G
Sbjct: 1165 -----SGSSSTKMKPQGKPSSLMNPSLSKPNISPSHSRPPGGS-----DKLASPMKPVPG 1214
Query: 2332 SHHQQSADSSRHSGIGHGQASSAVRDSGHRGSSG-------SQASDSEGHSEDSDTQSVS 2384
+ A S SG G S SG + SSG SQ + +S + + S S
Sbjct: 1215 TPPSSKAKSPISSGSGGSHMSGTSSSSGMKSSSGLGSSGSLSQKTPPSSNSCTASSSSFS 1274
Query: 2385 AHGQAGPHQQSHQESTRGRSAGR-------------------SGRSGSFLYQ----VSTH 2421
+ G + Q+ S++G+S R SG G VST+
Sbjct: 1275 SSGSSMSSSQNQHGSSKGKSPSRNKKPSLTAVIDKLKHGVVTSGPGGEDPLDGQMGVSTN 1334
Query: 2422 EQSESAHGRTGTSTGGRQGSHHKQARDSSRHSTSQEGQDTIHGHPGSSSGGRQGSHYEQL 2481
S + S G QG K +D S+ STS D+ S + G G +
Sbjct: 1335 SSSHPMSSKHNMSGGEFQGKREKSDKDKSKVSTSGSSVDSSKKTSESKNVGSTGVAKIII 1394
Query: 2482 VDRSGHSGSHHSHTTSQGRSDASHGHSGSRSASRQTRNDEQSGDGSRHSGSRHHEASSRA 2541
G S S + T Q G S Q + + G + HE S +
Sbjct: 1395 SKHDGGSPSIKAKVTLQ-----KPGESSGEGLRPQMASSKNYGSPLISGSTPKHERGSPS 1449
Query: 2542 DSSGHSQVGQGQSEGPRTSRNWGSSFSQDSDSQGHSEDSERWSGSASRNHHGSAQEQLRD 2601
S + Q + + Q+S S S+D R S H +++ +
Sbjct: 1450 HSKSPAYTPQNLDSESESGSSIAEKSYQNSPS---SDDGIRPLPEYSTEKHKKHKKEKKK 1506
Query: 2602 GSRHPRSHQEDR 2613
R D+
Sbjct: 1507 VKDKDRDRDRDK 1518
Score = 59.3 bits (142), Expect = 8e-08
Identities = 156/772 (20%), Positives = 273/772 (35%), Gaps = 103/772 (13%)
Query: 2547 SQVGQGQSEGPRTSRNWGSSFS--QDSDSQGHSE----DSERWSGSASRNHHGSAQEQLR 2600
S + + S+ P TS + + + +DS S GHS+ DS+ + + + N + + +
Sbjct: 784 SDIAEEASKLPSTSDDCPAIGTPLRDSSSSGHSQSTLFDSDVFQTNNNENPYTDPADLIA 843
Query: 2601 DGSRHPRS-------------------HQEDRAGHGHSA-DSSRQSGTRHTQTSSGGQAA 2640
D + P S + + ++G G D S QSG QA
Sbjct: 844 DAAGSPSSDSPTNHFFHDGVDFNPDLLNSQSQSGFGEEYFDESSQSGDNDDFKGFASQAL 903
Query: 2641 SSH--EQARSSAGERH--GSHHQQSADSSRHSGIG-----------HGQASSAVRDSGHR 2685
++ GE G++ + D S S G H + + +G
Sbjct: 904 NTLGVPMLGGDNGETKFKGNNQADTVDFSIISVAGKALAPADLMEHHSGSQGPLLTTGDL 963
Query: 2686 GYSGSQASDNEGHSEDSDTQSV----SAHGQAG----SHQQSHQESARGRSGETSGHSGS 2737
G +Q EG+ + T S S G+ + +S + + + +T G S S
Sbjct: 964 GKEKTQKRVKEGNGTSNSTLSGPGLDSKPGKRSRTPSNDGKSKDKPPKRKKADTEGKSPS 1023
Query: 2738 FLYQVSTHEQSESSHGWTGPSTRGRQGSRHEQAQDSSRHSASQDGQDTIR-GHP------ 2790
S+ G P + GR + A Q + T+ G P
Sbjct: 1024 HSSSNRPFTPPTSTGGSKSPGSAGRSQTPPGVATPPIPKITIQIPKGTVMVGKPSSHSQY 1083
Query: 2791 ---GSSRGGRQGYHHEHSVDSSGHSGSHHSHTTSQGRSDASRGQSGSRSASRTTRNEEQS 2847
GS HH HS SS + + +S+ +S S S +S+ + QS
Sbjct: 1084 TSSGSVSSSGSKSHHSHSSSSSSSASTSGKMKSSKSEGSSSSKLSSSMYSSQGSSGSSQS 1143
Query: 2848 GDGSRHSGSRHHEASTHADISRHSQAVQGQSEGSRRSRRQGSSVSQDSDSEGHSEDSERW 2907
+ S+ G T +S S + + + +G + S S+S+ + S HS R
Sbjct: 1144 KNSSQSGGKPGSSPITKHGLSSGSSSTKMKPQG-KPSSLMNPSLSKPNISPSHS----RP 1198
Query: 2908 SGSASRNHHGSAQEQLRDGSRHPRSHQEDRAGHGHSADSSRQSGTRHTQTSSGGQAASSH 2967
G + + S +S +G H + +S SG + SS G +S
Sbjct: 1199 PGGSDKLASPMKPVPGTPPSSKAKSPISSGSGGSHMSGTSSSSGMK----SSSGLGSSG- 1253
Query: 2968 EQARSSAGERHGSHHQQSADSSRHSGIGHGQASSAVRDSGHRGYSGSQASDNEGHSEDSD 3027
S + + S + +A SS S G +SS + H G S N+ S +
Sbjct: 1254 ----SLSQKTPPSSNSCTASSSSFSSSGSSMSSS---QNQHGSSKGKSPSRNKKPSLTAV 1306
Query: 3028 TQSVSAHG--QAGSHQQSHQESARGRSGETSGHSGSFLYQVSTHE----QSESSHGWTGP 3081
+ HG +G + + G S +S H S + +S E + +S +
Sbjct: 1307 IDKLK-HGVVTSGPGGEDPLDGQMGVSTNSSSHPMSSKHNMSGGEFQGKREKSDKDKSKV 1365
Query: 3082 STRGRQGSRHEQAQDSSRHSASQYGQDTIRGHPGSSRGGRQGYHHEHSVDSSGH------ 3135
ST G ++ +S ++ + I H G S + + +SSG
Sbjct: 1366 STSGSSVDSSKKTSESKNVGSTGVAKIIISKHDGGSPSIKAKVTLQKPGESSGEGLRPQM 1425
Query: 3136 --SGSHHSHTTSQGRSDASRGQ-SGSRSASRTTRNEEQSGDSSRHSVSRHHEASTHAD-- 3190
S ++ S S RG S S+S + T +N + +S + ++ S +D
Sbjct: 1426 ASSKNYGSPLISGSTPKHERGSPSHSKSPAYTPQNLDSESESGSSIAEKSYQNSPSSDDG 1485
Query: 3191 --------ISRHSQAVQGQSEGSRRSRRQGSSVSQDSDSEGHSEDSERWSGS 3234
+H + + + + + R + +D + HS E WS S
Sbjct: 1486 IRPLPEYSTEKHKKHKKEKKKVKDKDRDRDRDKDRDK-KKSHSIKPESWSKS 1536
Score = 50.4 bits (119), Expect = 3e-05
Identities = 74/301 (24%), Positives = 111/301 (36%), Gaps = 59/301 (19%)
Query: 3691 SHQESTRGRSAGRSGRSGSFLYQVSTHEQSESAHGRAGPSTGGRQGSRHEQARDSSRHS- 3749
SH + T S SG S H S S+ A ST G+ S + SS+ S
Sbjct: 1079 SHSQYTSSGSVSSSGSK-------SHHSHSSSSSSSA--STSGKMKSSKSEGSSSSKLSS 1129
Query: 3750 ---ASQEGQDTIRGHPGSRRGGRQGSYHEQSVDRSG-HSGSHHSHTTSQGRSDASHGQSG 3805
+SQ + + S+ GG+ GS + + G SGS + QG+ + S
Sbjct: 1130 SMYSSQGSSGSSQSKNSSQSGGKPGS---SPITKHGLSSGSSSTKMKPQGKPSSLMNPSL 1186
Query: 3806 SRSASRETRNEEQSGDGSRHSGSR---------------------HHEASTQADSSRHSQ 3844
S+ + + G S + H + T + S S
Sbjct: 1187 SKPNISPSHSRPPGGSDKLASPMKPVPGTPPSSKAKSPISSGSGGSHMSGTSSSSGMKSS 1246
Query: 3845 SGQGESAGSRRSRRQGSSVSQDSDSEAYPEDSERRSESASRNHHGSSREQSRDGSRHPG- 3903
SG G S+GS + SS S + S ++ S S S+S+N HGSS+ +S ++ P
Sbjct: 1247 SGLG-SSGSLSQKTPPSSNSCTASSSSF--SSSGSSMSSSQNQHGSSKGKSPSRNKKPSL 1303
Query: 3904 SSHRDTASH--VQSSPVQSDSSTAKEHGHFSSLSQDSAYHSGIQSRGSPHSSSSYHYQSE 3961
++ D H V S P D + G+ + S H SS H S
Sbjct: 1304 TAVIDKLKHGVVTSGPGGEDPLDGQ---------------MGVSTNSSSHPMSSKHNMSG 1348
Query: 3962 G 3962
G
Sbjct: 1349 G 1349
Score = 42.7 bits (99), Expect = 0.007
Identities = 47/194 (24%), Positives = 71/194 (36%), Gaps = 16/194 (8%)
Query: 3819 SGDGSRHSGSRHHEASTQADSSRHSQSGQGESAGSRRSRRQGSSVSQDSDSEAYPEDSER 3878
+GD + + + +S S G G R S+D + D+E
Sbjct: 960 TGDLGKEKTQKRVKEGNGTSNSTLSGPGLDSKPGKRSRTPSNDGKSKDKPPKRKKADTEG 1019
Query: 3879 RSESASRNHHGSSREQSRDGSRHPGSSHR-DTASHVQSSPV--------QSDSSTAKEHG 3929
+S S S ++ + S GS+ PGS+ R T V + P+ + K
Sbjct: 1020 KSPSHSSSNRPFTPPTSTGGSKSPGSAGRSQTPPGVATPPIPKITIQIPKGTVMVGKPSS 1079
Query: 3930 HFSSLSQDSAYHSGIQSRGSPHSSSSYHYQSEG---TERQKGQSGLVWRHGSYGSADYDY 3986
H S S SG +S S SSSS + G + + +G S Y S
Sbjct: 1080 HSQYTSSGSVSSSGSKSHHSHSSSSSSSASTSGKMKSSKSEGSSSSKLSSSMYSS----Q 1135
Query: 3987 GESGFRHSQHGSVS 4000
G SG S++ S S
Sbjct: 1136 GSSGSSQSKNSSQS 1149
>gi|7656879 ALL1 fused gene from 5q31 [Homo sapiens]
Length = 1163
Score = 84.3 bits (207), Expect = 2e-15
Identities = 178/889 (20%), Positives = 304/889 (34%), Gaps = 140/889 (15%)
Query: 1244 ADSSRHSQVGQEQSSGSRTSRHQGSSVSQDSDSERHSDDSERLSG-----SASRNHHGSS 1298
AD + +++ GS HQ S + + S +R SG S+ R GSS
Sbjct: 86 ADEKSNPNFFEQRHGGS----HQSSKWTPVGPAPSTSQSQKRSSGLQSGHSSQRTSAGSS 141
Query: 1299 REQSRDGSRHPGFHQEDRASHGHSADSSRQSGTHHTESSSHGQAVSSHEQARSSPGERHG 1358
+ G RH DR S+ +S SSR+ G H +E S + QA SS H
Sbjct: 142 SGTNSSGQRH------DRESYNNSGSSSRKKGQHGSEHSKSRSSSPGKPQAVSSLNSSHS 195
Query: 1359 SRHQQSADSSRHSGIGHRQASSAVRDSGHRGSSGSQVTNSEG-HSEDSDTQSVSAHGQA- 1416
H S H Q S + RD S S+V S G HS S S+ + +
Sbjct: 196 RSHGNDHHSKEH------QRSKSPRDPDANWDSPSRVPFSSGQHSTQSFPPSLMSKSNSM 249
Query: 1417 ------------GPHQQSHKESARGQSGESSGRSRSFLYQVSSHEQS------------- 1451
G K S+ S +S G S + L S +
Sbjct: 250 LQKPTAYVRPMDGQESMEPKLSSEHYSSQSHGNSMTELKPSSKAHLTKLKIPSQPLDASA 309
Query: 1452 ------------ESTHGQTAPSTGGRQGSRHEQARNSSRHSASQDGQ----DTIRGHPGS 1495
E TH P T + E ++ SQ + R +P
Sbjct: 310 SGDVSCVDEILKEMTHSWPPPLTAIHTPCKTEPSKFPFPTKESQQSNFGTGEQKRYNPSK 369
Query: 1496 SRGGRQGSYHEQSVDRSGHSGYHHSHTTPQGRSDASHGQSGPRSASRQTRNEEQSGDGSR 1555
+ G Q +S+ + + + D + +S P S S + + + D SR
Sbjct: 370 TSNGHQS----KSMLKDDLKLSSSEDSDGEQDCDKTMPRSTPGSNSEPSHHNSEGADNSR 425
Query: 1556 HSGSRHHEPSTRAGSSRHSQVGQGESAGSKTSRRQGSSVSQDRDSEGHSEDSERRSESAS 1615
S H + +GS S+ +S ++ S+ S + E + + +
Sbjct: 426 DDSSSHSGSESSSGSDSESESSSSDSEANEPSQ------SASPEPEPPPTNKWQLDNWLN 479
Query: 1616 RNHYGSAREQSRHGSRNPRSHQEDRASHGHSAESSRQSGTRHAETSSGGQAASSQEQARS 1675
+ + S S P +S G+ E R+ GT ++ T + G +E + +
Sbjct: 480 KVNPHKVSPASSVDSNIP-------SSQGYKKE-GREQGTGNSYTDTSG----PKETSSA 527
Query: 1676 SPGERHGSRHQQSADSSTDSGTGRRQDSSVVGDSGNRGSSG-SQASDSEGHSEESDTQSV 1734
+PG R ++ ++SG GR++ + + R + G Q +E + E +
Sbjct: 528 TPG-----RDSKTIQKGSESGRGRQKSPAQSDSTTQRRTVGKKQPKKAEKAAAEEPRGGL 582
Query: 1735 SAHGQAGPHQQSHQESTRGQSGERSGRSGSFLYQVSTHEQSESAHGRTGPSTGGRQRSRH 1794
+ S S+R ++ + R + + ++S+S+ R
Sbjct: 583 KIESETPVDLASSMPSSRHKAATKGSR------KPNIKKESKSS-----------PRPTA 625
Query: 1795 EQARDSSRHSASQEGQDTIRGHPGSSRGGRQGSHYEQSVDSSGHSGSH-HSHTTSQERSD 1853
E+ + S +SQ+ ++ I SS S +S+ S + + S+ T + S
Sbjct: 626 EKKKYKSTSKSSQKSREIIETDTSSS-----DSDESESLPPSSQTPKYPESNRTPVKPSS 680
Query: 1854 VSRGQSGSRSVSRQTRNEKQSGDGSRHSGSRHHEASSRADSSRHSQVGQGQSSGPRTSRN 1913
V S R EK+ R + + D + +++ +
Sbjct: 681 VEEEDSFFRQRMFSPMEEKELLSPLSEPDDR-YPLIVKIDLNLLTRIPGKPYKETEPPKG 739
Query: 1914 QGSSVSQDSDSQGHSEDSERWSGSASRNHLGSAWEQSRDGSRHPGSHHEDRAGHGHSADS 1973
+ +V + + + SE+ S R H E S ED+ GH S
Sbjct: 740 EKKNVPEKHTREAQKQASEKVSNKGKRKHKN---EDDNRASESKKPKTEDKNSAGHKPSS 796
Query: 1974 SRQSGTRHTESSSRGQAASSHEQARSSAGERHGSHHQLQSADSSRHSGIGHGQASSAVRD 2033
+R+ SS+ AA + S AG + S D HG +
Sbjct: 797 NRE--------SSKQSAAKEKDLLPSPAG-------PVPSKDPKTE----HGSRKRTISQ 837
Query: 2034 SGHRGYSGSQASDSEGHSEDSDTQS--VSAQGKAGPHQQSHKESARGQS 2080
S S + ++ G S++S + S +GK + KE A S
Sbjct: 838 SSSLKSSSNSNKETSGSSKNSSSTSKQKKTEGKTSSSSKEVKEKAPSSS 886
Score = 80.5 bits (197), Expect = 3e-14
Identities = 175/852 (20%), Positives = 294/852 (34%), Gaps = 88/852 (10%)
Query: 262 SSDGKSSSQVNRSRHENTSQVPLQESRTRKRRGSRVSQDRDSEGHSEDSERHSG-----S 316
S+D KS+ RH + Q S+ + + S+ +R SG S
Sbjct: 85 SADEKSNPNFFEQRHGGSHQ------------SSKWTPVGPAPSTSQSQKRSSGLQSGHS 132
Query: 317 ASRNHHGSAWEQSRDGSRHPRSHDEDRASHGHSADSSRQSGTRHAETSSRGQTASSHEQA 376
+ R GS+ + G RH DR S+ +S SSR+ G +E S ++ QA
Sbjct: 133 SQRTSAGSSSGTNSSGQRH------DRESYNNSGSSSRKKGQHGSEHSKSRSSSPGKPQA 186
Query: 377 RSSPGERHGSGHQQSADSSRHSATGRGQASSAVSDRGHRG--SSGSQASDSEGHSENSDT 434
SS H H S H + + A D R SSG ++ S S S +
Sbjct: 187 VSSLNSSHSRSHGNDHHSKEHQRSKSPRDPDANWDSPSRVPFSSGQHSTQSFPPSLMSKS 246
Query: 435 QSVSGHGKAGLRQQSHQESTRGRSGERSGRSGSSLYQVSTHEQPDSAHGRTGTSTGGRQG 494
S+ A +R QES + +S+ +HG + T
Sbjct: 247 NSMLQKPTAYVRPMDGQESMEPK--------------LSSEHYSSQSHGNSMTELKPSSK 292
Query: 495 SHHEQARDSSRH-SASQEG---------QDTIRGHPGSSRGGRQGSHHEQSVNRSGHSGS 544
+H + + S+ AS G ++ P E S S
Sbjct: 293 AHLTKLKIPSQPLDASASGDVSCVDEILKEMTHSWPPPLTAIHTPCKTEPSKFPFPTKES 352
Query: 545 HHSH--TTSQGRSDASHGQSGSRSASRQTRNEEQSGDGTRHSGSRHHEASSQADSSRHSQ 602
S+ T Q R + S +G +S S D + S S + D +
Sbjct: 353 QQSNFGTGEQKRYNPSKTSNGHQSKSMLK-------DDLKLSSSEDSDGEQDCDKTMPRS 405
Query: 603 VGQGQSSGPRTSRNQGSSVSQDSDSQGHSEDSERWSGSASRNHHGSAQEQSRDGSRHPRS 662
G +S P ++G+ S+D DS HS SE SGS S + S+ ++ + S+
Sbjct: 406 T-PGSNSEPSHHNSEGADNSRD-DSSSHS-GSESSSGSDSESESSSSDSEANEPSQSASP 462
Query: 663 HHEDRAGHGHSADSSRKSGTRHTQNSSSGQAASSHEQARSSAGERHGSRHQLQSADSSRH 722
E + D+ H + +S S SS G + R Q +
Sbjct: 463 EPEPPPTNKWQLDNWLNKVNPHKVSPAS----SVDSNIPSSQGYKKEGREQGTGNSYTDT 518
Query: 723 SGTGHGQASSAVRDSG--HRGSSGSQATDSEGHSEDSDTQSVS-GHGQAGHHQQSHQESA 779
SG +++ RDS +GS + DS TQ + G Q +++ E
Sbjct: 519 SGPKETSSATPGRDSKTIQKGSESGRGRQKSPAQSDSTTQRRTVGKKQPKKAEKAAAEEP 578
Query: 780 RDRSGERSRRSGSFLYQVSTHKQSESSHGWTGPSTGVRQGSHH----EQARDNSRHSASQ 835
R S + + + ++ G P+ S E+ + S +SQ
Sbjct: 579 RGGLKIESETPVDLASSMPSSRHKAATKGSRKPNIKKESKSSPRPTAEKKKYKSTSKSSQ 638
Query: 836 DGQDTIRGHPGSSRRGRQGSHHEQSVDRSGHSGSH-HSHTTSQGRSDASRGQSGSRSASR 894
++ I SS S +S+ S + + S+ T S S R
Sbjct: 639 KSREIIETDTSSS-----DSDESESLPPSSQTPKYPESNRTPVKPSSVEEEDSFFRQRMF 693
Query: 895 TTRNEEQSRDGSRHSGSRHHEASSHADISRHSQAGQGQSEGSRTSRRQGSSVSQDSDSEG 954
+ E++ R+ D++ ++ + + + + +V + E
Sbjct: 694 SPMEEKELLSPLSEPDDRY-PLIVKIDLNLLTRIPGKPYKETEPPKGEKKNVPEKHTREA 752
Query: 955 HSEDSERWSGSASRNHRGSAQEQSRHGSRHPRSHHEDRAGHGHSADSSRQSGTPHAETSS 1014
+ SE+ S R H+ E S + ED+ GH S+R+S A
Sbjct: 753 QKQASEKVSNKGKRKHKN---EDDNRASESKKPKTEDKNSAGHKPSSNRESSKQSAAKEK 809
Query: 1015 GGQAASSHEQARSSPGERHGSRHQQSADSS--RHSGIPRRQASSAVRDSGHWGSSGSQAS 1072
+ + P HGSR + + SS + S ++ S + ++S SS S+
Sbjct: 810 DLLPSPAGPVPSKDPKTEHGSRKRTISQSSSLKSSSNSNKETSGSSKNS----SSTSKQK 865
Query: 1073 DSEGHSEESDTQ 1084
+EG + S +
Sbjct: 866 KTEGKTSSSSKE 877
Score = 80.5 bits (197), Expect = 3e-14
Identities = 183/899 (20%), Positives = 311/899 (34%), Gaps = 120/899 (13%)
Query: 706 ERHGSRHQLQSADSSRHSGTGHGQASSAVRDSGHRGSSGSQATDSEGHSEDSDTQSVSGH 765
+RHG HQ SS+ + G ++S + SSG Q+ S S+ + S SG
Sbjct: 97 QRHGGSHQ-----SSKWTPVGPAPSTS----QSQKRSSGLQSGHS---SQRTSAGSSSGT 144
Query: 766 GQAGHHQQSHQESARDRSGERSRRSGSFLYQVSTHKQSESSHGWTGPSTGVRQGSHHEQA 825
+G Q H + + SG SR+ G S H +S SS P S H ++
Sbjct: 145 NSSG---QRHDRESYNNSGSSSRKKGQ---HGSEHSKSRSSSPGK-PQAVSSLNSSHSRS 197
Query: 826 RDNSRHSASQDGQDTIRGHPGSSRRGRQGSHHEQSVDRSGHSGSHHSHTTSQGRSDASRG 885
N HS S+ R + S R S HS T S S S+
Sbjct: 198 HGNDHHSKEHQ----------RSKSPRDPDANWDSPSRVPFSSGQHS-TQSFPPSLMSKS 246
Query: 886 QSGSRSASRTTRNEEQSRDGSRHSGSRHHEASSHADISRHSQAGQGQSEGSRTSRRQGSS 945
S + + R + S H+ + SH + S S + ++ + S
Sbjct: 247 NSMLQKPTAYVRPMDGQESMEPKLSSEHYSSQSHGN----SMTELKPSSKAHLTKLKIPS 302
Query: 946 VSQDSDSEGH--------SEDSERWSGSASRNHRGSAQE------------QSRHGSRHP 985
D+ + G E + W + H E QS G+
Sbjct: 303 QPLDASASGDVSCVDEILKEMTHSWPPPLTAIHTPCKTEPSKFPFPTKESQQSNFGTGEQ 362
Query: 986 RSHHEDRAGHGHSADSSRQSGTPHAETS-SGGQAASSHEQARSSPGERHGSRHQQS--AD 1042
+ ++ + +GH + S + + + S G+ RS+PG H S AD
Sbjct: 363 KRYNPSKTSNGHQSKSMLKDDLKLSSSEDSDGEQDCDKTMPRSTPGSNSEPSHHNSEGAD 422
Query: 1043 SSRHSGIPRRQASSAVRDSGHWGSSGSQASDSEGHSEESDTQSVSGHGQDGPHQQ---SH 1099
+SR S H GS S SDSE S SD+++ P + ++
Sbjct: 423 NSRDDS------------SSHSGSESSSGSDSESESSSSDSEANEPSQSASPEPEPPPTN 470
Query: 1100 QESARDWSGGRSGRSGSFIYQVSTHEQSESAHGRTRTSTGRRQGSHHEQARDS--SRHSA 1157
+ +W + S V ++ S + + GR QG+ + S S+
Sbjct: 471 KWQLDNWLNKVNPHKVSPASSVDSNIPSSQGYKK----EGREQGTGNSYTDTSGPKETSS 526
Query: 1158 SQEGQDTIRAHPGSRRG-GRQGSHHEQSVDRSGHSGSHHSHTTSQGRSDASHGQSGSRSA 1216
+ G+D+ GS G GRQ S + D + + + A+ G
Sbjct: 527 ATPGRDSKTIQKGSESGRGRQKSPAQS--DSTTQRRTVGKKQPKKAEKAAAEEPRGGLKI 584
Query: 1217 SRQTRKDKQSG-DGSRH----SGSRHHEAASWADSSRHSQVGQEQSSGSRTSRHQGSSVS 1271
+T D S SRH GSR + SS +++ + S + +
Sbjct: 585 ESETPVDLASSMPSSRHKAATKGSRKPNIKKESKSSPRPTAEKKKYKSTSKSSQKSREII 644
Query: 1272 QDSDSERHSDDSERLSGSASRNHHGSSREQSRDGSRHPGFHQEDR--ASHGHSADSSRQS 1329
+ S SD+SE L S+ + E +R + +ED S ++
Sbjct: 645 ETDTSSSDSDESESLPPSSQTPKY---PESNRTPVKPSSVEEEDSFFRQRMFSPMEEKEL 701
Query: 1330 GTHHTESSSHGQAVSSHE--QARSSPG----ERHGSRHQQSADSSRHSGIGHRQASSAVR 1383
+ +E + + PG E + ++ +H+ +QAS V
Sbjct: 702 LSPLSEPDDRYPLIVKIDLNLLTRIPGKPYKETEPPKGEKKNVPEKHTREAQKQASEKVS 761
Query: 1384 DSGHRGSSGSQVTNSEGHSEDSDTQSVSAHGQAGPHQQSHKESARGQSGESSGRSRSFLY 1443
+ G R + + +S AG S++ES++ +S+ + + L
Sbjct: 762 NKGKR----KHKNEDDNRASESKKPKTEDKNSAGHKPSSNRESSK----QSAAKEKDLLP 813
Query: 1444 QVSSHEQSESTHGQTAPSTGGRQGSRHEQ-ARNSSRHSASQDGQDTIRGHPGSSRGGRQG 1502
+ S+ P T GSR +++SS S+S ++T GSS+
Sbjct: 814 SPAGPVPSKD------PKT--EHGSRKRTISQSSSLKSSSNSNKET----SGSSKNSSST 861
Query: 1503 SYHEQSVDRSGHSGYHHSHTTPQGRSDASHGQSGPRSASRQTRNEEQSGDGSRHSGSRH 1561
S +++ ++ S P S+ S P S + R + D +S +
Sbjct: 862 SKQKKTEGKTSSSSKEVKEKAPSSSSNCP--PSAPTLDSSKPRRTKLVFDDRNYSADHY 918
Score = 77.8 bits (190), Expect = 2e-13
Identities = 172/846 (20%), Positives = 296/846 (34%), Gaps = 132/846 (15%)
Query: 2204 RHSGSHHHE-------ASSWADSSRHSLVGQGQSSGPRTSRPRGSSVSQDSDSEGHSEDS 2256
RH GSH A S + S + S Q S RTS GSS +S + H +S
Sbjct: 98 RHGGSHQSSKWTPVGPAPSTSQSQKRSSGLQSGHSSQRTSA--GSSSGTNSSGQRHDRES 155
Query: 2257 ERRSGSASRN--HHGSAQEQSRDGS------------RHPRSHHEDRAGHGHSAESSRQ- 2301
SGS+SR HGS +SR S H RSH D H S +
Sbjct: 156 YNNSGSSSRKKGQHGSEHSKSRSSSPGKPQAVSSLNSSHSRSHGNDHHSKEHQRSKSPRD 215
Query: 2302 --------------SGTHHAENSSGGQAASSHEQARSSAGERHGSHHQQSAD----SSRH 2343
SG H ++ + S+ + Q+S + S +
Sbjct: 216 PDANWDSPSRVPFSSGQHSTQSFPPSLMSKSNSMLQKPTAYVRPMDGQESMEPKLSSEHY 275
Query: 2344 SGIGHGQASSAVRDSGHRGSSG----SQASDSEGHSEDSDTQSV---SAHGQAGP----H 2392
S HG + + ++ S + SQ D+ + S + H P H
Sbjct: 276 SSQSHGNSMTELKPSSKAHLTKLKIPSQPLDASASGDVSCVDEILKEMTHSWPPPLTAIH 335
Query: 2393 QQSHQESTRGRSAGRSGRSGSFLYQVSTHEQSESAHGRTGTSTGGRQGSHHKQARDSSRH 2452
E ++ + + +F T EQ + + TS G + S K S
Sbjct: 336 TPCKTEPSKFPFPTKESQQSNF----GTGEQKR--YNPSKTSNGHQSKSMLKDDLKLSSS 389
Query: 2453 STSQEGQDTIHGHPGSSSGGRQGSHYEQLVDRSGHSGSHHSHTTSQGRSDASHGHSGSRS 2512
S QD P S+ G S SHH+ + D S HSGS S
Sbjct: 390 EDSDGEQDCDKTMPRSTPG-------------SNSEPSHHNSEGADNSRDDSSSHSGSES 436
Query: 2513 ASRQTRNDEQSGDGSRHSGSRHHEASSRADSSGHSQVGQGQSEGPRTSR----NWGSSFS 2568
+S S S +SS ++++ SQ + E P T++ NW + +
Sbjct: 437 SS--------------GSDSESESSSSDSEANEPSQSASPEPEPPPTNKWQLDNWLNKVN 482
Query: 2569 QDSDSQGHSEDSERWSGSASRNHHGSAQEQLRDGSRHPRSHQEDRAGHGHSADSSR-QSG 2627
S S DS + +S+ + +EQ S S ++ + DS Q G
Sbjct: 483 PHKVSPASSVDS---NIPSSQGYKKEGREQGTGNSYTDTSGPKETSSATPGRDSKTIQKG 539
Query: 2628 TRHTQTSSGGQAASSHEQARSSAGERHGSHHQQSADSSRHSGI-----GHGQASSAVRDS 2682
+ + A S R + G++ +++A G+ +S++ S
Sbjct: 540 SESGRGRQKSPAQSDSTTQRRTVGKKQPKKAEKAAAEEPRGGLKIESETPVDLASSMPSS 599
Query: 2683 GHRGYSGSQASDNEGHSEDSDTQSVSAHGQAGSHQQSHQESAR----GRSGETSGHSGSF 2738
H+ + N S + + + S +S Q+S S S S S
Sbjct: 600 RHKAATKGSRKPNIKKESKSSPRPTAEKKKYKSTSKSSQKSREIIETDTSSSDSDESESL 659
Query: 2739 LYQVSTHEQSESSHGWTGPSTRGRQGSRHEQAQDSSRHSASQDGQDTIRGHPGSSRGGRQ 2798
T + ES+ PS+ + S Q R + + ++ + P S R
Sbjct: 660 PPSSQTPKYPESNRTPVKPSSVEEEDSFFRQ-----RMFSPMEEKELL--SPLSEPDDR- 711
Query: 2799 GYHHEHSVD---SSGHSGSHHSHTTSQGRSDASRGQSGSRSASRTTRNEEQSGDGSRHSG 2855
Y +D + G + T + +G+ + T ++Q+ + + G
Sbjct: 712 -YPLIVKIDLNLLTRIPGKPYKET------EPPKGEKKNVPEKHTREAQKQASEKVSNKG 764
Query: 2856 SRHHEASTHADISRHSQAVQGQSEGSRRSRRQGSSVSQDSDSEGHSEDSERWSGSAS--- 2912
R H+ + D +R S++ + ++E + + SS +++S + +++ + A
Sbjct: 765 KRKHK---NEDDNRASESKKPKTEDKNSAGHKPSS-NRESSKQSAAKEKDLLPSPAGPVP 820
Query: 2913 ----RNHHGSAQEQLRDGSRHPRSHQEDRAGHGHSADSSRQSGTRHTQTSSGGQAASSHE 2968
+ HGS + + S S ++ G S +SS S + T+ + + E
Sbjct: 821 SKDPKTEHGSRKRTISQSSSLKSSSNSNKETSGSSKNSSSTSKQKKTEGKTSSSSKEVKE 880
Query: 2969 QARSSA 2974
+A SS+
Sbjct: 881 KAPSSS 886
Score = 72.8 bits (177), Expect = 7e-12
Identities = 166/864 (19%), Positives = 284/864 (32%), Gaps = 122/864 (14%)
Query: 2541 ADSSGHSQVGQGQSEGPRTSRNWGSSFSQDSDSQGHSEDSERWSG-SASRNHHGSAQEQL 2599
AD + + + G S W S SQ S SG S+ R GS+
Sbjct: 86 ADEKSNPNFFEQRHGGSHQSSKWTPVGPAPSTSQSQKRSSGLQSGHSSQRTSAGSSSGTN 145
Query: 2600 RDGSRHPRSHQEDRAGHGHSADSSR---QSGTRHTQTSSGG----QAASS--HEQARSSA 2650
G RH DR + +S SSR Q G+ H+++ S QA SS +RS
Sbjct: 146 SSGQRH------DRESYNNSGSSSRKKGQHGSEHSKSRSSSPGKPQAVSSLNSSHSRSHG 199
Query: 2651 GERHGSHHQQSA---------DSSRHSGIGHGQASSAVRDSGHRGYSGSQASDNEGHSED 2701
+ H HQ+S DS GQ S+ S S +
Sbjct: 200 NDHHSKEHQRSKSPRDPDANWDSPSRVPFSSGQHSTQSFPPSLMSKSNSMLQKPTAYVRP 259
Query: 2702 SDTQSVSAHGQAGSH--QQSHQESARGRSGETSGH-----------SGSFLYQVSTHEQ- 2747
D Q + H QSH S + H S VS ++
Sbjct: 260 MDGQESMEPKLSSEHYSSQSHGNSMTELKPSSKAHLTKLKIPSQPLDASASGDVSCVDEI 319
Query: 2748 -SESSHGWTGPSTRGRQGSRHEQAQDSSRHSASQDGQDTIRGHPGSSRGGRQGYHHEHSV 2806
E +H W P T + E ++ SQ S+ G + + S
Sbjct: 320 LKEMTHSWPPPLTAIHTPCKTEPSKFPFPTKESQQ----------SNFGTGEQKRYNPSK 369
Query: 2807 DSSGHSGSHHSHTTSQGRSDASRGQSGSRSASRTTRNEEQSGDGSRHSGSRHHEASTHAD 2866
S+GH S + +S G + +T +S GS S H+ S AD
Sbjct: 370 TSNGHQSK--SMLKDDLKLSSSEDSDGEQDCDKTM---PRSTPGSNSEPSHHN--SEGAD 422
Query: 2867 ISRHSQAVQGQSEGSRRSRRQGSSVSQDSDSEGHSEDS--------------ERWSGSAS 2912
SR + SE S S + S S DS++ S+ + + W +
Sbjct: 423 NSRDDSSSHSGSESSSGSDSESESSSSDSEANEPSQSASPEPEPPPTNKWQLDNWLNKVN 482
Query: 2913 RNHHGSAQEQLRDGSRHPRSHQEDRAGHGHSADSSRQSGTRHTQTSSGGQAASSHEQARS 2972
H S + + ++++ G + SG + T +++ G+ + + ++
Sbjct: 483 -PHKVSPASSVDSNIPSSQGYKKEGREQGTGNSYTDTSGPKETSSATPGRDSKTIQKGSE 541
Query: 2973 SAGERHGSHHQQSADSSRHSGIGHGQASSAVRDSGHRGYSGSQASDNEGHSEDSDTQSVS 3032
S R S Q + + R + +G Q A + + G + +S+T
Sbjct: 542 SGRGRQKSPAQSDSTTQRRT-VGKKQPKKAEKAAAEEPRGGLKI--------ESETPVDL 592
Query: 3033 AHGQAGSHQQSHQESARGRSGETSGHSGSFLYQVSTHEQSESSHGWTGPSTRGRQGSRHE 3092
A S ++ + +R + + ++S+SS T E
Sbjct: 593 ASSMPSSRHKAATKGSR---------------KPNIKKESKSSPRPTA-----------E 626
Query: 3093 QAQDSSRHSASQYGQDTIRGHPGSSRGGRQGYHHEHSVDSSGHSGSHHSHTTSQGRSDAS 3152
+ + S +SQ ++ I SS S+ S + + + + +
Sbjct: 627 KKKYKSTSKSSQKSREIIETDTSSSDS-----DESESLPPSSQTPKYPESNRTPVKPSSV 681
Query: 3153 RGQSGSRSASRTTRNEEQSGDSSRHSVSRHHEASTHADISRHSQAVQGQSEGSRRSRRQG 3212
+ + EE+ S + D++ ++ + + + +
Sbjct: 682 EEEDSFFRQRMFSPMEEKELLSPLSEPDDRYPLIVKIDLNLLTRIPGKPYKETEPPKGEK 741
Query: 3213 SSVSQDSDSEGHSEDSERWSGSASRNHRGSVQEQSRHGSRHPRSHHEDRAGHGHSADRSR 3272
+V + E + SE+ S R H+ E S + ED+ GH +R
Sbjct: 742 KNVPEKHTREAQKQASEKVSNKGKRKHK---NEDDNRASESKKPKTEDKNSAGHKPSSNR 798
Query: 3273 QSGTRHAETSSGGQAASSHEQARSSPGERHGSRHQQSADSSRHSGIPRGQASSAVRDSRH 3332
+S + A + + P HGSR + + SS SS+ +
Sbjct: 799 ESSKQSAAKEKDLLPSPAGPVPSKDPKTEHGSRKRTISQSS-------SLKSSSNSNKET 851
Query: 3333 WGSSGSQASDSEGHSEESDTQSVS 3356
GSS + +S S+ E T S S
Sbjct: 852 SGSSKNSSSTSKQKKTEGKTSSSS 875
Score = 72.8 bits (177), Expect = 7e-12
Identities = 166/840 (19%), Positives = 277/840 (32%), Gaps = 102/840 (12%)
Query: 2928 RHPRSHQEDRAGHGHSADSSRQSGTRHTQTSSGGQAASSHEQARSSAGERHGSHHQQSAD 2987
RH SHQ + A S+ QS R SSG Q S H R+SAG G++ +
Sbjct: 98 RHGGSHQSSKWTPVGPAPSTSQSQKR----SSGLQ--SGHSSQRTSAGSSSGTN----SS 147
Query: 2988 SSRHSGIGHGQASSAVRDSGHRGYSGSQASDNEGHSEDSDTQSVSAHGQAGS---HQQSH 3044
RH + + S+ R G G S++ + + + S+H ++ H + H
Sbjct: 148 GQRHDRESYNNSGSSSRKKGQHGSEHSKSRSSSPGKPQAVSSLNSSHSRSHGNDHHSKEH 207
Query: 3045 QESARGRSGE-----------TSGHSGSFLYQVSTHEQSESSHGWTGPSTRGRQGSRHEQ 3093
Q S R + +SG + + S +S S R G +
Sbjct: 208 QRSKSPRDPDANWDSPSRVPFSSGQHSTQSFPPSLMSKSNSMLQKPTAYVRPMDGQESME 267
Query: 3094 AQDSSRHSASQ-YGQDTIRGHPGSSRGGRQGYHHEHSVDSSGHSGSHHSHTTSQGRSDAS 3152
+ SS H +SQ +G P S + +D+S S + + +
Sbjct: 268 PKLSSEHYSSQSHGNSMTELKPSSKAHLTKLKIPSQPLDASA---SGDVSCVDEILKEMT 324
Query: 3153 RGQSGSRSASRTTRNEEQSGDSSRHSVSRHHEASTHADISRHSQAVQGQSEGSRRSRRQG 3212
+A T E S S+ T + R++ + S+ +
Sbjct: 325 HSWPPPLTAIHTPCKTEPSKFPFPTKESQQSNFGT-GEQKRYNPSKTSNGHQSKSMLKDD 383
Query: 3213 SSVSQDSDSEGHSEDSERWSGSASRNHRGSVQEQSRHGSRHPRSHHEDRAGHGHSADRSR 3272
+S DS+G + + + R+ GS E S H S + +D + H S S
Sbjct: 384 LKLSSSEDSDGEQDCDK----TMPRSTPGSNSEPSHHNSEGADNSRDDSSSH--SGSESS 437
Query: 3273 QSGTRHAETSSGGQAASSHEQARSSPGERHGSR-------------HQQSADSSRHSGIP 3319
+E+SS A+ Q+ S E + H+ S SS S IP
Sbjct: 438 SGSDSESESSSSDSEANEPSQSASPEPEPPPTNKWQLDNWLNKVNPHKVSPASSVDSNIP 497
Query: 3320 RGQASSAVRDSRHWGSSGSQASDSEGHSEESDTQSVSGHGQAGPHQQSHQESARDRSGGR 3379
Q ++ R G+ G+ +D+ G E S G+ Q ES R R +
Sbjct: 498 SSQGYK--KEGREQGT-GNSYTDTSGPKETSSATP----GRDSKTIQKGSESGRGRQ--K 548
Query: 3380 SGRSGSFLYQVSTHEQSESAHGRTRTSTGRRQGSHHEQ--------ARDSSRHSASQEG- 3430
S Q T + + + R G E + SSRH A+ +G
Sbjct: 549 SPAQSDSTTQRRTVGKKQPKKAEKAAAEEPRGGLKIESETPVDLASSMPSSRHKAATKGS 608
Query: 3431 -QDTIRGHPGSSRRGRQGSHYEQSVDRSGHSGSHHSHT-TSQGRSDASRGQSGSRSASRQ 3488
+ I+ SS R +S +S T TS SD S S +
Sbjct: 609 RKPNIKKESKSSPRPTAEKKKYKSTSKSSQKSREIIETDTSSSDSDESESLPPSSQTPKY 668
Query: 3489 TRND----EQSGDGSRHSWSHHHEASTQADSSRHSQSGQGQSAGP--------------- 3529
++ + S S+ S + S + P
Sbjct: 669 PESNRTPVKPSSVEEEDSFFRQRMFSPMEEKELLSPLSEPDDRYPLIVKIDLNLLTRIPG 728
Query: 3530 ------RTSRNQGSSVSQDSDSQGHSEDSERWSGSASRNHRGSAQEQSRDGSRHPTSHHE 3583
+ + +V + + + SE+ S R H+ ++ + + T E
Sbjct: 729 KPYKETEPPKGEKKNVPEKHTREAQKQASEKVSNKGKRKHKNEDDNRASESKKPKT---E 785
Query: 3584 DRAGHGHSAESSRQSGTHHAEN------SSGGQAASSHEQARSSAGERHGSHHQQSADSS 3637
D+ GH S+R+S A S G S + + +R S SS
Sbjct: 786 DKNSAGHKPSSNRESSKQSAAKEKDLLPSPAGPVPSKDPKTEHGSRKRTISQSSSLKSSS 845
Query: 3638 RHSGIGHGQASSAVRDSGHRGSSGSQASDSEGHSEDSDTQSVSAHGQAGPHQQSHQESTR 3697
+ G + ++ S + + G +S S+ E + + S + A S T+
Sbjct: 846 NSNKETSGSSKNSSSTSKQKKTEGKTSSSSKEVKEKAPSSSSNCPPSAPTLDSSKPRRTK 905
Score = 72.4 bits (176), Expect = 9e-12
Identities = 164/827 (19%), Positives = 288/827 (34%), Gaps = 95/827 (11%)
Query: 257 YERSRSSDGKSSSQVNRSRHENTSQVPLQESRTRKRRGSRVSQDRDSEGHSEDSERH--- 313
+E+ +SS +TSQ + S + S+ + S G + +RH
Sbjct: 95 FEQRHGGSHQSSKWTPVGPAPSTSQSQKRSSGLQSGHSSQRTSAGSSSGTNSSGQRHDRE 154
Query: 314 ----SGSASR--NHHGSAWEQSRD------------GSRHPRSHDEDRASHGHSADSSRQ 355
SGS+SR HGS +SR S H RSH D S H S +
Sbjct: 155 SYNNSGSSSRKKGQHGSEHSKSRSSSPGKPQAVSSLNSSHSRSHGNDHHSKEHQRSKSPR 214
Query: 356 SGTRHAETSSRGQTASSHEQARSSPGERHGSGHQQSADSSRHSATGRGQ-------ASSA 408
+ ++ SR +S +S P + + + GQ +S
Sbjct: 215 DPDANWDSPSRVPFSSGQHSTQSFPPSLMSKSNSMLQKPTAYVRPMDGQESMEPKLSSEH 274
Query: 409 VSDRGHRGSSGSQASDSEGHSEN----SDTQSVSGHGKAGLRQQSHQESTRGRSGERSGR 464
S + H S S+ H S S G + +E T +
Sbjct: 275 YSSQSHGNSMTELKPSSKAHLTKLKIPSQPLDASASGDVSCVDEILKEMTHSWPPPLTAI 334
Query: 465 SGSSLYQVSTHEQPDSAHGRTGTSTGGRQGSHHEQARDSSRHSASQEGQDTIRGHPGSSR 524
+ S P ++ TG + + ++ S+ H + +D ++
Sbjct: 335 HTPCKTEPSKFPFPTKESQQSNFGTG--EQKRYNPSKTSNGHQSKSMLKDDLKLSSSEDS 392
Query: 525 GGRQGSHHEQSVNRSGHSGSHHSHTTSQGRSDASHGQSGSRSASRQTRNEEQSGDGTRHS 584
G Q + G S S SH S+G +D S S S S S E SG S
Sbjct: 393 DGEQDCDKTMPRSTPG-SNSEPSHHNSEG-ADNSRDDSSSHSGS-----ESSSG-----S 440
Query: 585 GSRHHEASSQADSSRHSQVGQGQSSGPRTSR----NQGSSVSQDSDSQGHSEDSERWSGS 640
S +SS ++++ SQ + P T++ N + V+ S S DS +
Sbjct: 441 DSESESSSSDSEANEPSQSASPEPEPPPTNKWQLDNWLNKVNPHKVSPASSVDS---NIP 497
Query: 641 ASRNHHGSAQEQSRDGSRHPRSHHEDRAGHGHSADSSR-KSGTRHTQNSSSGQAASSHEQ 699
+S+ + +EQ S S ++ + DS + G+ + A S
Sbjct: 498 SSQGYKKEGREQGTGNSYTDTSGPKETSSATPGRDSKTIQKGSESGRGRQKSPAQSDSTT 557
Query: 700 ARSSAGERHGSRHQLQSADSSR-----HSGTGHGQASSAVRDSGHRGSSGSQATDSEGHS 754
R + G++ + + +A+ R S T ASS + GS+ + + S
Sbjct: 558 QRRTVGKKQPKKAEKAAAEEPRGGLKIESETPVDLASSMPSSRHKAATKGSRKPNIKKES 617
Query: 755 EDS---DTQSVSGHGQAGHHQQSHQESARDRSGERSRRSGSFLYQVSTHKQSESSHGWTG 811
+ S + + Q+S + D S S S S T K ES+
Sbjct: 618 KSSPRPTAEKKKYKSTSKSSQKSREIIETDTSSSDSDESESLPPSSQTPKYPESNRTPVK 677
Query: 812 PSTGVRQGSHHEQARDNSRHSASQDGQDTIRGHPGSSRRGRQGSHHEQSVD-RSGHSGSH 870
PS+ + S Q R + + ++ + P S R + ++ + G
Sbjct: 678 PSSVEEEDSFFRQ-----RMFSPMEEKELL--SPLSEPDDRYPLIVKIDLNLLTRIPGKP 730
Query: 871 HSHTTSQGRSDASRGQSGSRSASRTTRNEEQSRDGSRHSGSRHHEASSHADISRHSQAGQ 930
+ T + +G+ + T ++Q+ + + G R H+ + D +R S++ +
Sbjct: 731 YKET------EPPKGEKKNVPEKHTREAQKQASEKVSNKGKRKHK---NEDDNRASESKK 781
Query: 931 GQSEGSRTSRRQGSSVSQDSDSEGHSEDSERWSG--SASRNHRGSAQEQSRHGSRHPRSH 988
++E D +S GH S R S SA++ S+ P++
Sbjct: 782 PKTE--------------DKNSAGHKPSSNRESSKQSAAKEKDLLPSPAGPVPSKDPKTE 827
Query: 989 HEDRAGHGHSADSSRQSGTPHAETSSGGQAASSHEQARSSPGERHGS 1035
H R + S + S + ETS + +SS + + + G+ S
Sbjct: 828 HGSRKRTISQSSSLKSSSNSNKETSGSSKNSSSTSKQKKTEGKTSSS 874
Score = 70.1 bits (170), Expect = 4e-11
Identities = 180/877 (20%), Positives = 291/877 (33%), Gaps = 143/877 (16%)
Query: 1860 GSRSVSRQTRNEKQSGDGSRHSGSRHHEASSRADSSRHSQVGQGQSSGPRTSRNQGSSVS 1919
G RS+ + K + S S + R S S P TS++Q S
Sbjct: 67 GDRSIPKLVAIPKPTVPPSADEKSNPNFFEQRHGGSHQSSKWTPVGPAPSTSQSQKRSSG 126
Query: 1920 QDSDSQGHSEDSERWSGSASRNHLGSAWEQSRDGSRHPGSHHEDRAGHGHSADSSRQSGT 1979
S GHS + R GS+ + G RH DR + +S SSR+
Sbjct: 127 LQS---GHS---------SQRTSAGSSSGTNSSGQRH------DRESYNNSGSSSRK--- 165
Query: 1980 RHTESSSRGQAASSHEQARSSAGERHGSHHQLQSADSSRHSGIGHG---QASSAVRDSGH 2036
+GQ S H ++RSS+ + + L S+ S H H Q S + RD
Sbjct: 166 -------KGQHGSEHSKSRSSSPGKPQAVSSLNSSHSRSHGNDHHSKEHQRSKSPRDPDA 218
Query: 2037 RGYSGSQASDSEG-HSEDSDTQSVSAQGKAGPHQQSHKESARGQSGESSGRSGSFLYQVS 2095
S S+ S G HS S S+ K+ Q R G+ S ++S
Sbjct: 219 NWDSPSRVPFSSGQHSTQSFPPSL--MSKSNSMLQKPTAYVRPMDGQESMEP-----KLS 271
Query: 2096 THEQSESTHGQSAPSTGGRQGSHYDQAQDSSRH-SASQEG---------QDTIRGHP--- 2142
+ S +HG S +H + + S+ AS G ++ P
Sbjct: 272 SEHYSSQSHGNSMTELKPSSKAHLTKLKIPSQPLDASASGDVSCVDEILKEMTHSWPPPL 331
Query: 2143 ---------GPSRGGRQGSHQEQSVDRSGHSGSHHSHTTSQGRSDASRGQSGSRSASRKT 2193
PS+ +QS +G ++ TS G S + + +S +
Sbjct: 332 TAIHTPCKTEPSKFPFPTKESQQSNFGTGEQKRYNPSKTSNGHQSKSMLKDDLKLSSSED 391
Query: 2194 YDKEQSGD--------GSRHSGSHHHEASSWADSSRHSLVGQGQSSGPRTSRPRGSSVSQ 2245
D EQ D GS SHH+ S AD+SR S SS
Sbjct: 392 SDGEQDCDKTMPRSTPGSNSEPSHHN--SEGADNSRDDSSSHSGSE---------SSSGS 440
Query: 2246 DSDSEGHSEDSERRSGSASR---------------------NHHGSAQEQSRDGSRHPRS 2284
DS+SE S DSE S S N H + S D S P S
Sbjct: 441 DSESESSSSDSEANEPSQSASPEPEPPPTNKWQLDNWLNKVNPHKVSPASSVD-SNIPSS 499
Query: 2285 HHEDRAGHGHSAESSRQSGTHHAENSSGGQAASSHE-QARSSAGERHGSHHQQSADSSRH 2343
+ G +S + E SS S Q S +G QS +++
Sbjct: 500 QGYKKEGREQGTGNSYTDTSGPKETSSATPGRDSKTIQKGSESGRGRQKSPAQSDSTTQR 559
Query: 2344 SGIGHGQASSAVRDSGHRGSSG----SQASDSEGHSEDSDTQSVSAHGQAGPHQQSHQES 2399
+G Q A + + G S+ S S + G P+ + +S
Sbjct: 560 RTVGKKQPKKAEKAAAEEPRGGLKIESETPVDLASSMPSSRHKAATKGSRKPNIKKESKS 619
Query: 2400 TRGRSAGR-----SGRSGSFLYQVSTHEQSESAHGRTGTSTGGRQGSHHKQARDSSRHST 2454
+ +A + + +S ++ + S S + + Q + ++ + +
Sbjct: 620 SPRPTAEKKKYKSTSKSSQKSREIIETDTSSSDSDESESLPPSSQTPKYPESNRTPVKPS 679
Query: 2455 SQEGQDT---------IHGHPGSSSGGRQGSHYEQLVD-----RSGHSGSHHSHTTSQGR 2500
S E +D+ + S Y +V + G + T
Sbjct: 680 SVEEEDSFFRQRMFSPMEEKELLSPLSEPDDRYPLIVKIDLNLLTRIPGKPYKETEPPKG 739
Query: 2501 SDASHGHSGSRSASRQTRNDEQSGDGSRHSGSRHHEASSRADSSGHSQVGQGQSEGPRTS 2560
+ +R A +Q +++ S G R +E +RA S + S G + S
Sbjct: 740 EKKNVPEKHTREAQKQA-SEKVSNKGKR---KHKNEDDNRASESKKPKTEDKNSAGHKPS 795
Query: 2561 RNWGSSFSQDSDSQGHSEDSERWSGSAS-------RNHHGSAQEQLRDGSRHPRSHQEDR 2613
N ++S Q +++ + A + HGS + + S S ++
Sbjct: 796 SN------RESSKQSAAKEKDLLPSPAGPVPSKDPKTEHGSRKRTISQSSSLKSSSNSNK 849
Query: 2614 AGHGHSADSSRQSGTRHTQTSSGGQAASSHEQARSSA 2650
G S +SS S + T+ + + E+A SS+
Sbjct: 850 ETSGSSKNSSSTSKQKKTEGKTSSSSKEVKEKAPSSS 886
Score = 70.1 bits (170), Expect = 4e-11
Identities = 177/873 (20%), Positives = 300/873 (34%), Gaps = 129/873 (14%)
Query: 2487 HSGSHHSH---------TTSQGRSDAS---HGHSGSRSASRQTRNDEQSGDGSRHSGSRH 2534
H GSH S +TSQ + +S GHS R+++ S G+ SG RH
Sbjct: 99 HGGSHQSSKWTPVGPAPSTSQSQKRSSGLQSGHSSQRTSA-------GSSSGTNSSGQRH 151
Query: 2535 HEASSRADSSGHSQVGQGQSEGPRTSRNWGSSFSQDSDSQGHSEDSERWSGSASRNHHGS 2594
S S + GQ SE ++ S S G + + S SR+H
Sbjct: 152 DRESYNNSGSSSRKKGQHGSEHSKSR----------SSSPGKPQAVSSLNSSHSRSHGND 201
Query: 2595 AQEQLRDGSRHPRSHQEDRAGHGHSADSSRQSGTRHTQTSSGGQAASSHEQARSSAGERH 2654
+ S+ PR + SS Q T+ S ++ S ++ +
Sbjct: 202 HHSKEHQRSKSPRDPDANWDSPSRVPFSSGQHSTQSFPPSLMSKSNSMLQKPTAYVRPMD 261
Query: 2655 GSHHQQSADSSRH-SGIGHGQASSAVRDSGHRGYSGSQ-ASDNEGHSEDSDTQSVSAHGQ 2712
G + SS H S HG + + ++ S + + S S D V +
Sbjct: 262 GQESMEPKLSSEHYSSQSHGNSMTELKPSSKAHLTKLKIPSQPLDASASGDVSCVDEILK 321
Query: 2713 AGSHQQSHQESARGRSGETSGHSGSFLYQVSTHEQSESSHGWTG------PSTRGRQGSR 2766
+H +A +T F T E +S+ G TG PS
Sbjct: 322 EMTHSWPPPLTAIHTPCKTEPSKFPF----PTKESQQSNFG-TGEQKRYNPSKTSNGHQS 376
Query: 2767 HEQAQDSSRHSASQDG---QDTIRGHPGSSRGGRQGYHHEHSV-------DSSGHSGSHH 2816
+D + S+S+D QD + P S+ G H +S DSS HSGS
Sbjct: 377 KSMLKDDLKLSSSEDSDGEQDCDKTMPRSTPGSNSEPSHHNSEGADNSRDDSSSHSGS-E 435
Query: 2817 SHTTSQGRSDASRGQSGSRSASRTTRNEEQSGDGSRH------SGSRHHEASTHADISRH 2870
S + S S++S S + S++ E + ++ + H+ S + + +
Sbjct: 436 SSSGSDSESESSSSDSEANEPSQSASPEPEPPPTNKWQLDNWLNKVNPHKVSPASSVDSN 495
Query: 2871 SQAVQGQSEGSRRSRRQGSSVSQDSDSEGHSEDSERWSGSASRNHHGSAQEQLRDGSRHP 2930
+ QG + R QG+ S +D+ G E S G S+ ++ GS
Sbjct: 496 IPSSQGY---KKEGREQGTGNSY-TDTSGPKETSSATPGRDSKT--------IQKGSESG 543
Query: 2931 RSHQEDRAGHGHSADSSRQSGTRHTQTSSGGQAASSHEQAR----------SSAGERHGS 2980
R Q+ A +DS+ Q T + + A++ E A S
Sbjct: 544 RGRQKSPA----QSDSTTQRRTVGKKQPKKAEKAAAEEPRGGLKIESETPVDLASSMPSS 599
Query: 2981 HHQQSADSSRHSGIGHGQASSAVRDSGHRGYSGSQAS--------DNEGHSEDSD-TQSV 3031
H+ + SR I SS + + Y + S + + S DSD ++S+
Sbjct: 600 RHKAATKGSRKPNIKKESKSSPRPTAEKKKYKSTSKSSQKSREIIETDTSSSDSDESESL 659
Query: 3032 SAHGQAGSHQQSHQESARGRSGETSGHSGSFLYQ--VSTHEQSESSHGWTGPSTR----- 3084
Q + +S++ + S E SF Q S E+ E + P R
Sbjct: 660 PPSSQTPKYPESNRTPVKPSSVE---EEDSFFRQRMFSPMEEKELLSPLSEPDDRYPLIV 716
Query: 3085 -----------GRQGSRHEQAQDSSRHSASQYGQDTIRGHPGSSRGGRQGYHHEHSVDSS 3133
G+ E + ++ ++ ++ + S + +G + D +
Sbjct: 717 KIDLNLLTRIPGKPYKETEPPKGEKKNVPEKHTREAQK--QASEKVSNKGKRKHKNEDDN 774
Query: 3134 GHSGSHHSHT---TSQGRSDASRGQSGSRSASR------TTRNEEQSGDSSRHSVSRHHE 3184
S S T S G +S +S +SA++ + S D SR
Sbjct: 775 RASESKKPKTEDKNSAGHKPSSNRESSKQSAAKEKDLLPSPAGPVPSKDPKTEHGSRKRT 834
Query: 3185 ASTHADISRHSQAVQGQSEGSRRSRRQGSSVSQDSDSEGHSEDSERWSGSASRNHRGSVQ 3244
S + + S + + S S+ S + + S++ + + S+S N S
Sbjct: 835 ISQSSSLKSSSNSNKETSGSSKNSSSTSKQKKTEGKTSSSSKEVKEKAPSSSSNCPPSAP 894
Query: 3245 EQSRHGSRHPRSHHEDRAGHGHSADRSRQSGTR 3277
R + +DR +SAD Q +
Sbjct: 895 TLDSSKPRRTKLVFDDR---NYSADHYLQEAKK 924
Score = 66.6 bits (161), Expect = 5e-10
Identities = 173/859 (20%), Positives = 289/859 (33%), Gaps = 134/859 (15%)
Query: 3168 EEQSGDSSRHSVSRHHEASTHADISRHSQAVQGQSEGSRRSRRQ-GSSVSQDSDSEGHSE 3226
E++ G S H S+ S+ + G G R GSS +S + H
Sbjct: 96 EQRHGGS--HQSSKWTPVGPAPSTSQSQKRSSGLQSGHSSQRTSAGSSSGTNSSGQRHDR 153
Query: 3227 DSERWSGSASRNHRGSVQEQSRHGSRHPRSHHEDRAGHGHSADRSRQSGTRHAETSSGGQ 3286
+S SGS+SR ++ +HGS H +S RS G A +S
Sbjct: 154 ESYNNSGSSSR-------KKGQHGSEHSKS-------------RSSSPGKPQAVSSLN-- 191
Query: 3287 AASSHEQARSSPGERHGSRHQQSADSSRHSGIPRGQASSAVRDSRHWGSSGSQASDSEGH 3346
SSH +RS + H HQ+S PR ++ SR SSG ++ S
Sbjct: 192 --SSH--SRSHGNDHHSKEHQRSKS-------PRDPDANWDSPSRVPFSSGQHSTQSFPP 240
Query: 3347 SEESDTQSVSGHGQAGPHQQSHQESARDRSGGRSGRSGSFLYQVSTHEQSESAHGRTRTS 3406
S S + S+ A QES + +S+ S +HG + T
Sbjct: 241 SLMSKSNSMLQKPTAYVRPMDGQESMEPK--------------LSSEHYSSQSHGNSMTE 286
Query: 3407 TGRRQGSHHEQARDSSRH-SASQEG---------QDTIRGHP------------GSSRRG 3444
+H + + S+ AS G ++ P S+
Sbjct: 287 LKPSSKAHLTKLKIPSQPLDASASGDVSCVDEILKEMTHSWPPPLTAIHTPCKTEPSKFP 346
Query: 3445 RQGSHYEQSVDRSGHSGSHHSHTTSQGRSDASRGQSGSRSASRQTRNDEQSGD------- 3497
+QS +G ++ TS G S + + +S + + EQ D
Sbjct: 347 FPTKESQQSNFGTGEQKRYNPSKTSNGHQSKSMLKDDLKLSSSEDSDGEQDCDKTMPRST 406
Query: 3498 -GSRHSWSHHHEASTQADSSRHSQSGQGQSAGPRTSRNQGSSVSQDSD----SQGHSEDS 3552
GS SHH+ S AD+SR S S S ++ S S DS+ SQ S +
Sbjct: 407 PGSNSEPSHHN--SEGADNSRDDSSSHSGSESSSGSDSESESSSSDSEANEPSQSASPEP 464
Query: 3553 E-----RW--SGSASRNHRGSAQEQSRDGSRHPTSHHEDRAGHGHSAESSRQSGTHHAEN 3605
E +W ++ + S S P+S + G +S + E
Sbjct: 465 EPPPTNKWQLDNWLNKVNPHKVSPASSVDSNIPSSQGYKKEGREQGTGNSYTDTSGPKET 524
Query: 3606 SSGGQAASSHE-QARSSAGERHGSHHQQSADSSRHSGIGHGQASSAVRDSGHRGSSG--- 3661
SS S Q S +G QS +++ +G Q A + + G
Sbjct: 525 SSATPGRDSKTIQKGSESGRGRQKSPAQSDSTTQRRTVGKKQPKKAEKAAAEEPRGGLKI 584
Query: 3662 -SQASDSEGHSEDSDTQSVSAHGQAGPHQQSHQEST--------RGRSAGRSGRSGSFLY 3712
S+ S S + G P+ + +S+ + +S +S + +
Sbjct: 585 ESETPVDLASSMPSSRHKAATKGSRKPNIKKESKSSPRPTAEKKKYKSTSKSSQKSREII 644
Query: 3713 QVSTHEQSESAHGRAGPSTGGRQGSRHEQARDSSRHSASQEGQDTIRGHPGSRRGGRQGS 3772
+ T PS+ Q ++ ++ + +S E +D+ R S
Sbjct: 645 ETDTSSSDSDESESLPPSS---QTPKYPESNRTPVKPSSVEEEDSFFRQ-------RMFS 694
Query: 3773 YHEQSVDRSGHSGSHHSH-----------TTSQGR----SDASHGQSGSRSASRETRNEE 3817
E+ S S + T G+ ++ G+ + ++
Sbjct: 695 PMEEKELLSPLSEPDDRYPLIVKIDLNLLTRIPGKPYKETEPPKGEKKNVPEKHTREAQK 754
Query: 3818 QSGDGSRHSGSRHH--EASTQADSSRHSQSGQGESAGSR-RSRRQGSSVSQDSDSEAYPE 3874
Q+ + + G R H E +A S+ ++ SAG + S R+ S S + + P
Sbjct: 755 QASEKVSNKGKRKHKNEDDNRASESKKPKTEDKNSAGHKPSSNRESSKQSAAKEKDLLPS 814
Query: 3875 DSERRSESASRNHHGSSREQSRDGSRHPGSSHRDTASHVQSSPVQSDSSTAKEHGHFSSL 3934
+ + HGS + S SS+ + + S S S K G SS
Sbjct: 815 PAGPVPSKDPKTEHGSRKRTISQSSSLKSSSNSNKETSGSSKNSSSTSKQKKTEGKTSSS 874
Query: 3935 SQDSAYHSGIQSRGSPHSS 3953
S++ + S P S+
Sbjct: 875 SKEVKEKAPSSSSNCPPSA 893
Score = 65.9 bits (159), Expect = 8e-10
Identities = 171/836 (20%), Positives = 279/836 (33%), Gaps = 164/836 (19%)
Query: 2976 ERHGSHHQQSADSSRHSGIG------HGQASSAVRDSGHR------GYSGSQASDNEGHS 3023
+RHG HQ SS+ + +G Q S+ SGH G S S + H
Sbjct: 97 QRHGGSHQ----SSKWTPVGPAPSTSQSQKRSSGLQSGHSSQRTSAGSSSGTNSSGQRHD 152
Query: 3024 EDSDTQSVSAHGQAGSHQQSHQESARGRSGETSGHSGSFLYQVSTHEQSESSHGWTGPST 3083
+S S S+ + G H H +S G+ S S + SHG +
Sbjct: 153 RESYNNSGSSSRKKGQHGSEHSKSRSSSPGKPQAVS-------SLNSSHSRSHG-NDHHS 204
Query: 3084 RGRQGSRHEQAQDSSRHSASQYGQDTIRGHPGSSRGGRQGYHHEHSVDSSGHSGSHHSHT 3143
+ Q S+ + D++ S S+ P SS +HS S S S++
Sbjct: 205 KEHQRSKSPRDPDANWDSPSRV--------PFSSG--------QHSTQSFPPSLMSKSNS 248
Query: 3144 TSQGRSDASRGQSGSRSASRTTRNEEQSGDSSRHSVSRHHEASTHADISR---HSQAVQG 3200
Q + R G S +E S S +S++ + S+ A +++ SQ +
Sbjct: 249 MLQKPTAYVRPMDGQESMEPKLSSEHYSSQSHGNSMTEL-KPSSKAHLTKLKIPSQPLDA 307
Query: 3201 QSEGSRRSRRQGSSVSQDSDSEGHSEDSERWSGSASRNHRGSVQE------------QSR 3248
+ G S V + HS W + H E QS
Sbjct: 308 SASGDV------SCVDEILKEMTHS-----WPPPLTAIHTPCKTEPSKFPFPTKESQQSN 356
Query: 3249 HGSRHPRSHHEDRAGHGHSADRSRQSGTRHAETS-SGGQAASSHEQARSSPGERHGSRHQ 3307
G+ + ++ + +GH + + + + + S G+ RS+PG H
Sbjct: 357 FGTGEQKRYNPSKTSNGHQSKSMLKDDLKLSSSEDSDGEQDCDKTMPRSTPGSNSEPSHH 416
Query: 3308 QS--ADSSRHSGIPRGQASSAVRDSRHWGSSGSQASDSEGHSEESD------TQSVSGH- 3358
S AD+SR S H GS S SDSE S SD +QS S
Sbjct: 417 NSEGADNSRDDS------------SSHSGSESSSGSDSESESSSSDSEANEPSQSASPEP 464
Query: 3359 --------------GQAGPHQQSHQESARD---------RSGGRSGRSGSFLYQVSTHEQ 3395
+ PH+ S S + G G S+ E
Sbjct: 465 EPPPTNKWQLDNWLNKVNPHKVSPASSVDSNIPSSQGYKKEGREQGTGNSYTDTSGPKET 524
Query: 3396 SESAHGRTR------TSTGR-RQGSHHEQARDSSRHSASQEGQDTIRGHPGSSRRGRQGS 3448
S + GR + +GR RQ S + + R + ++ RG
Sbjct: 525 SSATPGRDSKTIQKGSESGRGRQKSPAQSDSTTQRRTVGKKQPKKAEKAAAEEPRGGLKI 584
Query: 3449 HYEQSVD-RSGHSGSHHSHTTSQGRSDASRGQSGSRSASRQTRNDEQSGDGSRHSWSHHH 3507
E VD S S H T R + + S+S+ R T ++ S+ S
Sbjct: 585 ESETPVDLASSMPSSRHKAATKGSRKPNIKKE--SKSSPRPTAEKKKYKSTSKSSQKSRE 642
Query: 3508 --EASTQADSSRHSQSGQGQSAGPRTSRNQGSSVSQDSDSQGHS----------EDSERW 3555
E T + S S+S S P+ + + V S + S E+ E
Sbjct: 643 IIETDTSSSDSDESESLPPSSQTPKYPESNRTPVKPSSVEEEDSFFRQRMFSPMEEKELL 702
Query: 3556 SGSASRNHR----------------GSAQEQSR--DGSRHPTSHHEDRAGHGHSAESSRQ 3597
S + + R G +++ G + R ++E
Sbjct: 703 SPLSEPDDRYPLIVKIDLNLLTRIPGKPYKETEPPKGEKKNVPEKHTREAQKQASEKVSN 762
Query: 3598 SGTHHAENSSGGQAASSHE---QARSSAGERHGSHHQQSADSSRH------SGIGHGQAS 3648
G +N +A+ S + + ++SAG + S+ + S S+ S G +
Sbjct: 763 KGKRKHKNEDDNRASESKKPKTEDKNSAGHKPSSNRESSKQSAAKEKDLLPSPAGPVPSK 822
Query: 3649 SAVRDSGHRGSSGSQASDSEGHSEDSDTQSVSAHGQAGPHQQSHQESTRGRSAGRS 3704
+ G R + SQ+S + S + S S+ + S Q+ T G+++ S
Sbjct: 823 DPKTEHGSRKRTISQSSSLKSSSNSNKETSGSSKNSS---STSKQKKTEGKTSSSS 875
Score = 65.5 bits (158), Expect = 1e-09
Identities = 161/830 (19%), Positives = 278/830 (33%), Gaps = 113/830 (13%)
Query: 2811 HSGSHHSHT-----TSQGRSDASRGQSGSRSASRTTRNEEQSGDGSRHSGSRHHEASTHA 2865
H GSH S + S + + SG +S + R S G+ SG RH
Sbjct: 99 HGGSHQSSKWTPVGPAPSTSQSQKRSSGLQSGHSSQRTSAGSSSGTNSSGQRH------- 151
Query: 2866 DISRHSQAVQGQSEGSRRSRRQGSSVSQD-SDSEGHSEDSERWSGSASRNHHGSAQEQLR 2924
R S G S SR+ + GS S+ S S G + + S SR+H +
Sbjct: 152 --DRESYNNSGSS--SRKKGQHGSEHSKSRSSSPGKPQAVSSLNSSHSRSHGNDHHSKEH 207
Query: 2925 DGSRHPRSHQEDRAGHGHSADSSRQSGTRHTQTSSGGQAASSHEQARSSAGERHGSHHQQ 2984
S+ PR + SS Q T+ S ++ S ++ + G +
Sbjct: 208 QRSKSPRDPDANWDSPSRVPFSSGQHSTQSFPPSLMSKSNSMLQKPTAYVRPMDGQESME 267
Query: 2985 SADSSRH-SGIGHGQASSAVRDSGHRGYSGSQA-SDNEGHSEDSDTQSVSAHGQAGSHQQ 3042
SS H S HG + + ++ S + + S S D V + +H
Sbjct: 268 PKLSSEHYSSQSHGNSMTELKPSSKAHLTKLKIPSQPLDASASGDVSCVDEILKEMTHSW 327
Query: 3043 SHQESARGRSGETSGHSGSFLYQVSTHEQSESSHGWTGPSTRGRQGSRHEQAQDSSRHSA 3102
+A +T F T E +S+ G TG + R+ ++ S+ H +
Sbjct: 328 PPPLTAIHTPCKTEPSKFPF----PTKESQQSNFG-TG------EQKRYNPSKTSNGHQS 376
Query: 3103 SQYGQDTIRGHPGSSRGGRQGYHHEHSVDSSGHSGSHHSHTTSQGRSDASRGQSGSRSAS 3162
+D ++ G Q + G S S SH S+G +D SR S S S S
Sbjct: 377 KSMLKDDLKLSSSEDSDGEQDCDKTMPRSTPG-SNSEPSHHNSEG-ADNSRDDSSSHSGS 434
Query: 3163 RTTRNEEQSGDSSRHSVSRHHEASTHADISRHSQAVQGQSEGSRRSRRQGSSVSQDSDSE 3222
++ + +SS S+ ++ + SQ+ + E ++ Q
Sbjct: 435 ESSSGSDSESESS----------SSDSEANEPSQSASPEPEPPPTNKWQ----------- 473
Query: 3223 GHSEDSERWSGSASRNHRGSVQEQSRHGSRHPRSHHEDRAGHGHSADRSRQSGTRHAETS 3282
+ W + + V S S P S + G S + ETS
Sbjct: 474 -----LDNWLNKVNPH---KVSPASSVDSNIPSSQGYKKEGREQGTGNSYTDTSGPKETS 525
Query: 3283 SGGQAASSHEQARSSPGERHGSRHQQSADSSRH----------------SGIPRG----- 3321
S S + S R + +DS+ + PRG
Sbjct: 526 SATPGRDSKTIQKGSESGRGRQKSPAQSDSTTQRRTVGKKQPKKAEKAAAEEPRGGLKIE 585
Query: 3322 -----QASSAVRDSRHWGSS-GSQASDSEGHSEES---DTQSVSGHGQAGPHQQSHQESA 3372
+S++ SRH ++ GS+ + + S+ S + + Q+S +
Sbjct: 586 SETPVDLASSMPSSRHKAATKGSRKPNIKKESKSSPRPTAEKKKYKSTSKSSQKSREIIE 645
Query: 3373 RDRSGGRSGRSGSFLYQVSTHEQSESAHGRTRTSTGRRQGSHHEQARDS--------SRH 3424
D S S S S T + ES + S+ + S Q S S
Sbjct: 646 TDTSSSDSDESESLPPSSQTPKYPESNRTPVKPSSVEEEDSFFRQRMFSPMEEKELLSPL 705
Query: 3425 SASQEGQDTIRGHPGSSRRGRQGSHYEQSVDRSGHSGSHHSHTTSQGRSDASRGQSGSRS 3484
S + I + G Y+++ G + T + + AS S
Sbjct: 706 SEPDDRYPLIVKIDLNLLTRIPGKPYKETEPPKGEKKNVPEKHTREAQKQASEKVSNKGK 765
Query: 3485 ASRQTRNDEQSGDGSR----------HSWSHHHEASTQADSSRH----SQSGQGQSAGPR 3530
+ +D ++ + + H S + E+S Q+ + S +G S P+
Sbjct: 766 RKHKNEDDNRASESKKPKTEDKNSAGHKPSSNRESSKQSAAKEKDLLPSPAGPVPSKDPK 825
Query: 3531 TSRNQGSSVSQDSDSQGHSEDSERWSGSASRNHRGSAQEQSRDGSRHPTS 3580
T S S S +S + + +S+N +++++ +G +S
Sbjct: 826 TEHGSRKRTISQSSSLKSSSNSNKETSGSSKNSSSTSKQKKTEGKTSSSS 875
Score = 64.3 bits (155), Expect = 2e-09
Identities = 162/828 (19%), Positives = 277/828 (33%), Gaps = 104/828 (12%)
Query: 1838 HSGSHHSHTTSQERSDVSRGQSGSRSVSRQTRNEKQ-----SGDGSRHSGSRHHE----- 1887
H GSH S + S QS RS Q+ + Q S G+ SG RH
Sbjct: 99 HGGSHQSSKWTPVGPAPSTSQSQKRSSGLQSGHSSQRTSAGSSSGTNSSGQRHDRESYNN 158
Query: 1888 --ASSRADSSRHSQVGQGQSSGPRTSRNQGSSVSQDSDSQGHSEDSERWSGSASRNHLGS 1945
+SSR S+ + +SS P + S S S S G+ S+ S S +
Sbjct: 159 SGSSSRKKGQHGSEHSKSRSSSPGKPQAVSSLNSSHSRSHGNDHHSKEHQRSKSPRDPDA 218
Query: 1946 AWEQSRDGSRHPGSHHEDRAGHGHSADSSRQSGTRHTESSSRGQAASSHEQARSSAGERH 2005
W+ SR P SS Q T+ S ++ S ++ +
Sbjct: 219 NWDSP---SRVP--------------FSSGQHSTQSFPPSLMSKSNSMLQKPTAYVRPMD 261
Query: 2006 GSHHQLQSADSSRHSGIGHGQASSAVRDSGHRGYS----GSQASDSEGHSEDSDTQSVSA 2061
G S +S HG + + ++ S + SQ D+ + S +
Sbjct: 262 GQESMEPKLSSEHYSSQSHGNSMTELKPSSKAHLTKLKIPSQPLDASASGDVSCVDEIL- 320
Query: 2062 QGKAGPHQQSHKESARGQSGESSGRSGSFLYQVSTHEQSESTHGQSAPSTGGRQGSHYDQ 2121
+ +H + + ++ + T E +S G TG + Y+
Sbjct: 321 ------KEMTHSWPPPLTAIHTPCKTEPSKFPFPTKESQQSNFG-----TG--EQKRYNP 367
Query: 2122 AQDSSRHSASQEGQDTIRGHPGPSRGGRQGSHQEQSVDRSGHSGSHHSHTTSQGRSDASR 2181
++ S+ H + +D ++ G Q + G S S SH S+G +D SR
Sbjct: 368 SKTSNGHQSKSMLKDDLKLSSSEDSDGEQDCDKTMPRSTPG-SNSEPSHHNSEG-ADNSR 425
Query: 2182 GQSGSRSASRKTYDKEQSGDGSRHSGSHHHEASSWAD-------SSRHSLVGQGQSSGPR 2234
S S S S + + + S S S +E S A +++ L P
Sbjct: 426 DDSSSHSGSESSSGSDSESESS-SSDSEANEPSQSASPEPEPPPTNKWQLDNWLNKVNPH 484
Query: 2235 TSRPRGSSVSQDSDSEGH-SEDSERRSGSASRNHHGSAQEQSRDGSRHPRSHHEDRAGHG 2293
P S S S+G+ E E+ +G++ + G + S R ++ +
Sbjct: 485 KVSPASSVDSNIPSSQGYKKEGREQGTGNSYTDTSGPKETSSATPGRDSKTIQKGSESGR 544
Query: 2294 HSAESSRQSGTHHAENSSGGQAASSHEQARSSAGERHGS---------HHQQSADSSRHS 2344
+S QS + + G + E+A +A E G S SSRH
Sbjct: 545 GRQKSPAQSDSTTQRRTVGKKQPKKAEKA--AAEEPRGGLKIESETPVDLASSMPSSRHK 602
Query: 2345 GIGHGQASSAVRDSGHRGSSGSQASDSEGHSEDSDTQSVSAHGQAGPHQQSHQESTRGRS 2404
G ++ + S S +E S ++S Q+S + S
Sbjct: 603 AATKGSRKPNIK----KESKSSPRPTAEKKKYKSTSKS---------SQKSREIIETDTS 649
Query: 2405 AGRSGRSGSFLYQVSTHEQSESAHGRTGTSTGGRQGSHHKQARDSSRH-----STSQEGQ 2459
+ S S S T + ES S+ + S +Q S S E
Sbjct: 650 SSDSDESESLPPSSQTPKYPESNRTPVKPSSVEEEDSFFRQRMFSPMEEKELLSPLSEPD 709
Query: 2460 D--------------TIHGHPGSSSGGRQGSHYEQLVDRSGHSGSHHSHTTS-QGRSDAS 2504
D I G P + +G + + S S +G+
Sbjct: 710 DRYPLIVKIDLNLLTRIPGKPYKETEPPKGEKKNVPEKHTREAQKQASEKVSNKGKRKHK 769
Query: 2505 HGHSGSRSASRQTRNDEQSGDGSRHSGSRHHEASSRADSSG--HSQVGQGQSEGPRTSRN 2562
+ S S++ + ++++ G + S +R S A S G S+ P+T
Sbjct: 770 NEDDNRASESKKPKTEDKNSAGHKPSSNRESSKQSAAKEKDLLPSPAGPVPSKDPKTEHG 829
Query: 2563 WGSSFSQDSDSQGHSEDSERWSGSASRNHHGSAQEQLRDGSRHPRSHQ 2610
S S S +S + + +S+N +++++ +G S +
Sbjct: 830 SRKRTISQSSSLKSSSNSNKETSGSSKNSSSTSKQKKTEGKTSSSSKE 877
Score = 59.7 bits (143), Expect = 6e-08
Identities = 143/818 (17%), Positives = 280/818 (34%), Gaps = 113/818 (13%)
Query: 106 HHDKHEDNK------QEENKENRKRPSSLERRNNRKGNKGRSKSPRETGGKRHESSSEKK 159
H H+ +K +++KR S L+ ++ + S S + G+RH+ S
Sbjct: 99 HGGSHQSSKWTPVGPAPSTSQSQKRSSGLQSGHSSQRTSAGSSSGTNSSGQRHDRESYNN 158
Query: 160 ERKGYSPTHREEEYGKNHHNSSKKEKNK--------TENTRLGDNRKRLSERLEEKEDNE 211
S + ++ ++G H S K + ++R N E K +
Sbjct: 159 SG---SSSRKKGQHGSEHSKSRSSSPGKPQAVSSLNSSHSRSHGNDHHSKEHQRSKSPRD 215
Query: 212 EGVYDYENTGRMTQKWIQSGHIATYYTIQDEAYDTTDSLLEENKIYER----SRSSDGKS 267
++++ R+ SG +T + ++S+L++ Y R S + K
Sbjct: 216 PDA-NWDSPSRVP---FSSGQHST-QSFPPSLMSKSNSMLQKPTAYVRPMDGQESMEPKL 270
Query: 268 SSQVNRSRHENTSQVPLQESRTRKRRGSRV-SQDRDSEGHSEDSERHSGSASRNHHGSAW 326
SS+ S+ S L+ S ++ SQ D+ + S H +W
Sbjct: 271 SSEHYSSQSHGNSMTELKPSSKAHLTKLKIPSQPLDASASGDVSCVDEILKEMTH---SW 327
Query: 327 -------------------------EQSRDGSRHPRSHDEDRASHGHSADSSRQSGTR-H 360
+QS G+ + ++ + S+GH + S + +
Sbjct: 328 PPPLTAIHTPCKTEPSKFPFPTKESQQSNFGTGEQKRYNPSKTSNGHQSKSMLKDDLKLS 387
Query: 361 AETSSRGQTASSHEQARSSPGERHGSGHQQS--ADSSRHSATGRGQASSAVSDRGHRGSS 418
+ S G+ RS+PG H S AD+SR ++ H GS
Sbjct: 388 SSEDSDGEQDCDKTMPRSTPGSNSEPSHHNSEGADNSRDDSS------------SHSGSE 435
Query: 419 GSQASDSEGHSENSDTQSVSGHGKAGLRQQ---SHQESTRGRSGERSGRSGSSLYQVSTH 475
S SDSE S +SD+++ A + +++ + + S V ++
Sbjct: 436 SSSGSDSESESSSSDSEANEPSQSASPEPEPPPTNKWQLDNWLNKVNPHKVSPASSVDSN 495
Query: 476 EQPDSAHGRTGTSTGGRQGSHHEQARDSSRHSASQEGQD--TIRGHPGSSRGGRQGSHHE 533
+ + G G G+ + S++ G+D TI+ S RG ++
Sbjct: 496 IPSSQGYKKEGREQG--TGNSYTDTSGPKETSSATPGRDSKTIQKGSESGRGRQKSPAQS 553
Query: 534 QSVNRSGHSGSHHSHTTSQGRSDASHGQSGSRSASRQTRNEEQSGDGTRH----SGSRHH 589
S + G + ++ G G + S + S +RH GSR
Sbjct: 554 DSTTQRRTVGKKQPKKAEKAAAEEPRG--GLKIESETPVDLASSMPSSRHKAATKGSRKP 611
Query: 590 EASSQADSSRHSQVGQGQSSGPRTSRNQGSSVSQDSDSQGHSEDSERWSGSASRNHH--- 646
++ SS + + S + + + S S++SE S+ +
Sbjct: 612 NIKKESKSSPRPTAEKKKYKSTSKSSQKSREIIETDTSSSDSDESESLPPSSQTPKYPES 671
Query: 647 -------GSAQEQSRDGSRHPRSHHEDR--AGHGHSADSSRKSGTRHTQNSSSGQAASSH 697
S +E+ + S E++ D + N + +
Sbjct: 672 NRTPVKPSSVEEEDSFFRQRMFSPMEEKELLSPLSEPDDRYPLIVKIDLNLLTRIPGKPY 731
Query: 698 EQARSSAGERHGSRHQLQSADSSRHSGTGHGQASSAVRDSGHRGSSGSQATDSEGHSEDS 757
++ GE+ +H+ QAS V + G R + + + +S
Sbjct: 732 KETEPPKGEKKNV--------PEKHTREAQKQASEKVSNKGKR----KHKNEDDNRASES 779
Query: 758 DTQSVSGHGQAGHHQQSHQESARDRSGERSRRSGSFLYQVSTHKQSESSHG----WTGPS 813
AGH S++ES++ + + S V + K ++ HG S
Sbjct: 780 KKPKTEDKNSAGHKPSSNRESSKQSAAKEKDLLPSPAGPVPS-KDPKTEHGSRKRTISQS 838
Query: 814 TGVRQGSH-HEQARDNSRHSASQDGQDTIRGHPGSSRR 850
+ ++ S+ +++ +S++S+S Q G SS +
Sbjct: 839 SSLKSSSNSNKETSGSSKNSSSTSKQKKTEGKTSSSSK 876
Score = 50.8 bits (120), Expect = 3e-05
Identities = 115/624 (18%), Positives = 224/624 (35%), Gaps = 89/624 (14%)
Query: 103 KHSHHDKHEDNKQEENKENRKRPSSLERRNNRKGNKGRSKS-PRETGGKRHESSSEKKER 161
+ ++ + + ++K K L + G + K+ PR T G E
Sbjct: 361 EQKRYNPSKTSNGHQSKSMLKDDLKLSSSEDSDGEQDCDKTMPRSTPGSNSE-------- 412
Query: 162 KGYSPTHREEEYGKNHHNSSKKEKNKTENTRLGDNRKRLSERLEEKEDNEEGVYDYENTG 221
P+H E N + S ++ + S E E ++ + E
Sbjct: 413 ----PSHHNSEGADNSRDDSSSHSGSESSSGSDSESESSSSDSEANEPSQSASPEPEPPP 468
Query: 222 RMTQKWIQSGHIATYYTIQDEAYDTTDSLLEENKIYERSRSSDGKSSSQVNRSRHENTSQ 281
T KW + + + DS + ++ Y++ G +S + S + TS
Sbjct: 469 --TNKWQLDNWLNKVNPHKVSPASSVDSNIPSSQGYKKEGREQGTGNSYTDTSGPKETSS 526
Query: 282 V-PLQESRTRKRRGSRVSQDRDSEGHSEDSERHSGSASRNH----HGSAWEQSRDGSRHP 336
P ++S+T ++ GS + R DS + + +A E+ R G +
Sbjct: 527 ATPGRDSKTIQK-GSESGRGRQKSPAQSDSTTQRRTVGKKQPKKAEKAAAEEPRGGLKIE 585
Query: 337 RSHDEDRASHGHSADSSRQSGTRHAETSSRGQTASSHEQARSSPGERHGSGHQQSADSSR 396
D AS S+ RH + + + ++++SSP + +A+ +
Sbjct: 586 SETPVDLASSMPSS--------RHKAATKGSRKPNIKKESKSSP--------RPTAEKKK 629
Query: 397 HSATGRGQASSAVSDRGHRGSSGSQASDSEGHSENSDTQSVSGHGKAGLRQQS-HQESTR 455
+ +T + S + +S S + +SE +S T + ++ S +E +
Sbjct: 630 YKSTSKSSQKSR--EIIETDTSSSDSDESESLPPSSQTPKYPESNRTPVKPSSVEEEDSF 687
Query: 456 GRSGERSGRSGSSLYQVSTHEQPDSAH---------------GRTGTSTGGRQGSHHEQA 500
R S L +S +PD + G+ T +G
Sbjct: 688 FRQRMFSPMEEKEL--LSPLSEPDDRYPLIVKIDLNLLTRIPGKPYKETEPPKGEKKNVP 745
Query: 501 RDSSRHSASQEGQDTIRGHPGSSRGGRQGSHHEQSVNRSGHSGSHHSHTTSQGRSDASHG 560
+R + Q + S++G R+ H + NR+ S ++ ++ A H
Sbjct: 746 EKHTREAQKQASEKV------SNKGKRK--HKNEDDNRASES----KKPKTEDKNSAGHK 793
Query: 561 QSGSRSASRQTRNEEQ-----------SGDGTRHSGSRHHEASSQADSSRHSQVGQGQSS 609
S +R +S+Q+ +E+ S D GSR SQ+ S + S ++S
Sbjct: 794 PSSNRESSKQSAAKEKDLLPSPAGPVPSKDPKTEHGSR-KRTISQSSSLKSSSNSNKETS 852
Query: 610 GPRTSRNQGSSVSQ---DSDSQGHSEDSERWSGSASRNHHGSAQEQSRDGSRHPRSHHED 666
G +S+N S+ Q + + S++ + + S+S N SA R + +D
Sbjct: 853 G--SSKNSSSTSKQKKTEGKTSSSSKEVKEKAPSSSSNCPPSAPTLDSSKPRRTKLVFDD 910
Query: 667 RAGHGHSADSSRKSGTRHTQNSSS 690
R +SAD + + N+ +
Sbjct: 911 R---NYSADHYLQEAKKLKHNADA 931
Score = 41.2 bits (95), Expect = 0.021
Identities = 77/393 (19%), Positives = 144/393 (36%), Gaps = 49/393 (12%)
Query: 88 STRKENLPIS-GHKHRKHSHHDKHEDNKQEENKENRKRPSSLERRNNRKGN---KGRSKS 143
S+ N+P S G+K + KE + + +KG+ +GR KS
Sbjct: 490 SSVDSNIPSSQGYKKEGREQGTGNSYTDTSGPKETSSATPGRDSKTIQKGSESGRGRQKS 549
Query: 144 P--------RETGGKRHESSSEK---KERKGYSPTHREEEYGKNHHNSSKKEKNKTENTR 192
P R T GK+ +EK +E +G E S + K T+ +R
Sbjct: 550 PAQSDSTTQRRTVGKKQPKKAEKAAAEEPRGGLKIESETPVDLASSMPSSRHKAATKGSR 609
Query: 193 LGDNRKRLSERLEEKEDNEEGVYDYENTGRMTQKWIQSGHIATYYTIQDEAYD------- 245
+ +K + ++ Y++T + +QK + T + DE+
Sbjct: 610 KPNIKKESKSSPRPTAEKKK----YKSTSKSSQKSREIIETDTSSSDSDESESLPPSSQT 665
Query: 246 ----------TTDSLLEENKIYERSRSSDGKSSSQVNRSRHENTSQVPL----QESRTRK 291
S +EE + R R ++ E + PL + +
Sbjct: 666 PKYPESNRTPVKPSSVEEEDSFFRQRMFSPMEEKELLSPLSEPDDRYPLIVKIDLNLLTR 725
Query: 292 RRGSRVSQDRDSEGHSED-SERHSGSASRNHHGSAWEQSRDGSRHPRSHDEDRASHGHSA 350
G + +G ++ E+H+ A + ++ + S G R ++ D++RAS
Sbjct: 726 IPGKPYKETEPPKGEKKNVPEKHTREAQKQ---ASEKVSNKGKRKHKNEDDNRASESKKP 782
Query: 351 DSSRQSGTRHAETSSR---GQTASSHEQARSSPGERHGSGHQQSADSSRHSATGRGQA-- 405
+ ++ H +S+R Q+A+ + SP S ++ SR + +
Sbjct: 783 KTEDKNSAGHKPSSNRESSKQSAAKEKDLLPSPAGPVPSKDPKTEHGSRKRTISQSSSLK 842
Query: 406 SSAVSDRGHRGSSGSQASDSEGHSENSDTQSVS 438
SS+ S++ GSS + +S S+ T S S
Sbjct: 843 SSSNSNKETSGSSKNSSSTSKQKKTEGKTSSSS 875
Score = 39.3 bits (90), Expect = 0.080
Identities = 43/193 (22%), Positives = 79/193 (40%), Gaps = 22/193 (11%)
Query: 38 EKEFRQILKNPDD--PDMVDVFMDHLDIDHNKKIDFTEFLLMVFKLAQAYY--ESTRKEN 93
EKE L PDD P +V + ++ L K TE K + E+ ++ +
Sbjct: 698 EKELLSPLSEPDDRYPLIVKIDLNLLTRIPGKPYKETEPPKGEKKNVPEKHTREAQKQAS 757
Query: 94 LPISGHKHRKHSHHDKHEDNKQEENKENRKRPSSLERRNNRKGNKGR------------- 140
+S RKH + D + ++ ++ K K + + +NR+ +K
Sbjct: 758 EKVSNKGKRKHKNEDDNRASESKKPKTEDKNSAGHKPSSNRESSKQSAAKEKDLLPSPAG 817
Query: 141 ---SKSPRETGGKRHESSSEKKERKGYSPTHREEEYGKNHHNSSKKEKNKTENTRLGDNR 197
SK P+ G R + S+ K S +++E G + ++SS ++ KTE + +
Sbjct: 818 PVPSKDPKTEHGSRKRTISQSSSLKSSSNSNKETS-GSSKNSSSTSKQKKTEG-KTSSSS 875
Query: 198 KRLSERLEEKEDN 210
K + E+ N
Sbjct: 876 KEVKEKAPSSSSN 888
Score = 36.6 bits (83), Expect = 0.52
Identities = 33/141 (23%), Positives = 51/141 (36%), Gaps = 8/141 (5%)
Query: 3824 RHSGSRHHEASTQADSSRHSQSGQGESAG-----SRRSRRQGSSVSQDSDSEAYPEDSER 3878
RH GS T + + Q S+G S + GSS +S + + +S
Sbjct: 98 RHGGSHQSSKWTPVGPAPSTSQSQKRSSGLQSGHSSQRTSAGSSSGTNSSGQRHDRESYN 157
Query: 3879 RSESASRNHHGSSREQSRDGSRHPGSSHRDTASHVQSSPVQSDSSTAKEHGHFSSLSQDS 3938
S S+SR E S+ S PG ++ + S + +KEH S
Sbjct: 158 NSGSSSRKKGQHGSEHSKSRSSSPGKPQAVSSLNSSHSRSHGNDHHSKEHQRSKSPRDPD 217
Query: 3939 A---YHSGIQSRGSPHSSSSY 3956
A S + HS+ S+
Sbjct: 218 ANWDSPSRVPFSSGQHSTQSF 238
>gi|207113162 Treacher Collins-Franceschetti syndrome 1 isoform e
[Homo sapiens]
Length = 1451
Score = 84.0 bits (206), Expect = 3e-15
Identities = 282/1511 (18%), Positives = 512/1511 (33%), Gaps = 177/1511 (11%)
Query: 663 HHEDRAGHGHSA-DSSRKSG---------------TRHTQNSSSGQAASSHEQARSSAGE 706
HH RAG+ +A + +SG T Q S G+ + E A A +
Sbjct: 16 HHLLRAGYVRAAREVKEQSGQKCFLAQPVTLLDIYTHWQQTSELGRKRKAEEDAALQAKK 75
Query: 707 RHGSRHQLQSADSSRHSGTGHGQASSAVRDSGHRGSS--GSQATDSEGHSEDSDTQSVSG 764
S + +++SS + + A SS G+ S ++T+
Sbjct: 76 TRVS-DPISTSESSEEEEEAEAETAKATPRLASTNSSVLGADLPSSMKEKAKAETEKAGK 134
Query: 765 HGQAGHHQQSHQESARDRSGERSRRSGSFLYQVSTHKQSESSHGWTGPSTGVRQGSHHEQ 824
G + H + + A SG+ R+S + ++E + G
Sbjct: 135 TGNSMPHPATGKTVANLLSGKSPRKSAEPSANTTLVSETEEEGSVPAFGAAAKPGMVSAG 194
Query: 825 ARDNSRHSASQDGQDT-IRGHPG---SSRRGRQGSHHEQSVDRSGHSGSHHSHTTSQGRS 880
D+S S +T + G P + + S E ++ + T Q +
Sbjct: 195 QADSSSEDTSSSSDETDVEGKPSVKPAQVKASSVSTKESPARKAAPAPGKVGDVTPQVKG 254
Query: 881 DASRGQSGSRSASRTTRNEEQSRDGSRHSGSRHHEASSHADISRHSQAGQGQSEGSRTSR 940
A ++ A + E S +GS E+ A SQ ++
Sbjct: 255 GAL---PPAKRAKKPEEESESSEEGS--------ESEEEAPAGTRSQV---KASEKILQV 300
Query: 941 RQGSSVSQDSDSEGHSEDSERWSGS-ASRNHRGSAQEQSRHGSRHPRSHHEDRAGHGHSA 999
R S+ ++ + +G + +G+ AS+ G +E S S S+
Sbjct: 301 RAASAPAKGTPGKGATPAPPGKAGAVASQTKAGKPEEDSESSSEE-------------SS 347
Query: 1000 DSSRQSGTPHAETSSGGQAASSHEQARSSPGERHGSRHQQSADSSRHSGIPRRQASSAVR 1059
DS ++ A + +S A S+P + + A P + AV
Sbjct: 348 DSEEETPAAKALLQAKASGKTSQVGAASAPAKESPRKGAAPA--------PPGKTGPAVA 399
Query: 1060 DSGHWGSSGSQASDSEGHSEESDTQSVSGHGQDGPHQQSHQESARDWSGGRSGRSGSFIY 1119
+ +G + DS+ SEESD++ Q P ++ Q A S R G+
Sbjct: 400 KA----QAGKREEDSQSSSEESDSEE-EAPAQAKPSGKAPQVRAASAPAKESPRKGA--- 451
Query: 1120 QVSTHEQSESAHGRTRTSTGRRQ-GSHHEQARDSSRHSASQEGQDTIRAHPGSRRGGRQG 1178
+ + +T + + Q G E +R SS S S + G+
Sbjct: 452 -------APAPPRKTGPAAAQVQVGKQEEDSRSSSEESDSDREALAAMNAAQVKPLGKSP 504
Query: 1179 SHHEQSVDRSGHSGSHHSHTTSQGRSDASHGQSGSRSASRQTRKDKQSGDGS--RHSGSR 1236
S G G +G G+ G + S Q K ++ + S S S
Sbjct: 505 QVKPASTMGMGPLG--------KGAGPVPPGKVGPATPSAQVGKWEEDSESSSEESSDSS 556
Query: 1237 HHEAASWADSSRHSQVG-----QEQSSGSRTSRHQGSSVSQDSDSERHSDDSERLSGSAS 1291
E + ++ +G + SS ++ + V+ +E+ D+SE
Sbjct: 557 DGEVPTAVAPAQEKSLGNILQAKPTSSPAKGPPQKAGPVAVQVKAEKPMDNSE------- 609
Query: 1292 RNHHGSSREQSRDGSRHPGFHQEDRASHGHSADSSRQSGTHHTESSSHGQAVSSHEQARS 1351
S E+S D + A+ A Q+ ++++ A + + +
Sbjct: 610 ------SSEESSDSADSEEAPAAMTAAQAKPALKIPQTKACPKKTNTTASAKVAPVRVGT 663
Query: 1352 SPGERHGSRHQQSADSSRHSGIGHRQA---SSAVRDSGHRGSSGSQVTNSEGHSEDSDTQ 1408
+ G+ + S +G R A SS+ +G VT + S Q
Sbjct: 664 QAPRKAGTATSPAGSSPAVAGGTQRPAEDSSSSEESDSEEEKTGLAVTVGQAKSVGKGLQ 723
Query: 1409 ----SVSAHGQAGPHQQSHKESARGQSGESSGRSRSFLYQVSSHEQSESTHGQTAPSTGG 1464
SV G G Q G++G + + ++ + S + ES + A S
Sbjct: 724 VKAASVPVKGSLG---QGTAPVLPGKTGPTVTQVKAEKQEDSESSEEESDSEEAAASPAQ 780
Query: 1465 RQGS-RHEQARNSSRHSASQDGQDTIRGHPGSSRGGRQGSYHEQSVDRSGHSGYHHSHTT 1523
+ S + QA+ + + + + TI Q S + +S
Sbjct: 781 VKTSVKKTQAKANPAAARAPSAKGTISAPGKVVTAAAQAKQRSPSKVKPPVRNPQNSTVL 840
Query: 1524 PQG-RSDASHGQSGPRSASRQTRNEEQSGDGSRHSGSRHH-EPSTRAGSSRHSQVGQGES 1581
+G S S G++ +A QT EE SG S S E + S + +
Sbjct: 841 ARGPASVPSVGKAVATAAQAQTGPEEDSGSSEEESDSEEEAETLAQVKPSGKTHQIRAAL 900
Query: 1582 AGSKTSRRQGSS------VSQDRDSEGHSEDSERRSESASRNHYGSAREQSRHGSRNP-- 1633
A +K S R+G++ G +DS SE + + A S + P
Sbjct: 901 APAKESPRKGAAPTPPGKTGPSAAQAGKQDDSGSSSEESDSDGEAPAAVTSAQVIKPPLI 960
Query: 1634 -----RSHQEDRASHGHSAESSRQSGTRHAETSSGGQAASSQEQ------ARSSPGERHG 1682
RS A+ + +S R +E+++ ++ S+++ +PG R
Sbjct: 961 FVDPNRSPAGPAATPAQAQAASTPRKARASESTARSSSSESEDEDVIPATQCLTPGIRTN 1020
Query: 1683 -----SRHQQSADSSTDSGTGRRQDSSVVGDSGNRGSSGSQASDSEGHSEESDTQSVSAH 1737
+ H + A ++ +G ++SS + D + +Q + G + QS S
Sbjct: 1021 VVTMPTAHPRIAPKASMAGASSSKESSRISDGKKQEGPATQVDSAVGTLPATSPQSTSVQ 1080
Query: 1738 GQA-----GPHQQSHQESTRG-----QSGERSGRSGSFLYQVSTHEQSESAHGRTGPSTG 1787
+ P Q++T+ S + S S + ++SAH GP+
Sbjct: 1081 AKGTNKLRKPKLPEVQQATKAPESSDDSEDSSDSSSGSEEDGEGPQGAKSAHTLVGPTPS 1140
Query: 1788 GRQRSRHEQARDSSRHSASQEGQDTIRGH--PGSSRGGRQGSHYEQSVDSSGHSGSHHSH 1845
+ E A +SS Q + G+ PG + Q S +DSS S +
Sbjct: 1141 RTETLVEETAAESSEDDVVAPSQSLLSGYMTPGLTPANSQASKATPKLDSSPSVSSTLAA 1200
Query: 1846 TTSQERSDVSRGQSGSRSVSRQT-RNEKQSGDGSRHS-----GSRHHEASSRADSSRHSQ 1899
+ ++ Q + +S +T E SG + S G+ + +AS+ A S +Q
Sbjct: 1201 KDDPDGKQEAKPQQAAGMLSPKTGGKEAASGTTPQKSRKPKKGAGNPQASTLALQSNITQ 1260
Query: 1900 VGQGQSSGPRTSRNQGSSVSQDSDSQGHSEDSERWSGSASRNHLGSAWEQ-------SRD 1952
GQ ++ Q S V ++ E + ++ WE +
Sbjct: 1261 CLLGQPWPLNEAQVQASVVKVLTEL---LEQERKKVVDTTKESSRKGWESRKRKLSGDQP 1317
Query: 1953 GSRHPGSHHEDRAGHGHSADSSRQSGTRHTESSSRGQA----ASSHEQARSSAGERHGSH 2008
+R P S + + G G ++S T ++S+G+A AS + + G GS
Sbjct: 1318 AARTPRSKKKKKLGAGEGGEAS--VSPEKTSTTSKGKAKRDKASGDVKEKKGKGSL-GSQ 1374
Query: 2009 HQLQSADSSRHSGIG--HGQASSAVRDSGHRGYSGSQASDSEGHSEDSDTQSVSAQGKAG 2066
+ G+G G S + + S + D E + + S +
Sbjct: 1375 GAKDEPEEELQKGMGTVEGGDQSNPKSKKEKKKSDKRKKDKEKKEKKKKAKKASTKDSES 1434
Query: 2067 PHQQSHKESAR 2077
P Q+ K+ +
Sbjct: 1435 PSQKKKKKKKK 1445
Score = 79.3 bits (194), Expect = 7e-14
Identities = 274/1475 (18%), Positives = 497/1475 (33%), Gaps = 194/1475 (13%)
Query: 389 QQSADSSRHSATGRGQASSAVSDRGHRGSSGSQASDSEGHSENSDTQSV-----SGHGKA 443
QQ+++ R A A R S S++S+ E +E ++ +
Sbjct: 54 QQTSELGRKRKAEEDAALQAKKTRVSDPISTSESSEEEEEAEAETAKATPRLASTNSSVL 113
Query: 444 GLRQQSHQESTRGRSGERSGRSGSSLYQVSTHEQPDSAHGRTGTST-GGRQGSHHEQARD 502
G S + E++G++G+S+ P A G+T + G+ +
Sbjct: 114 GADLPSSMKEKAKAETEKAGKTGNSM--------PHPATGKTVANLLSGKSPRKSAEPSA 165
Query: 503 SSRHSASQEGQDTIRGHPGSSRGGRQGSHHEQSVNRSGHSGSHHSHTTSQGRSDASHGQS 562
++ + E + ++ +++ G + S + S S T +G+ Q
Sbjct: 166 NTTLVSETEEEGSVPAFGAAAKPGMVSAGQADSSSEDTSSSS--DETDVEGKPSVKPAQV 223
Query: 563 GSRSASRQTRNEEQSGDGTRHSGSRHHEASSQADSSRHSQVGQGQSSGPRTSRNQGSSVS 622
+ S S T+ S +R + QV G P R +
Sbjct: 224 KASSVS------------TKESPARKAAPAPGKVGDVTPQVKGGAL--PPAKRAKKPEEE 269
Query: 623 QDSDSQGHSEDSERWSGSASRNHHGSAQEQSRDGSRHPRSHHEDRA-----GHGHSADSS 677
+S +G + E +G+ S+ Q R S + A G + S
Sbjct: 270 SESSEEGSESEEEAPAGTRSQVKASEKILQVRAASAPAKGTPGKGATPAPPGKAGAVASQ 329
Query: 678 RKSGTRHTQNSSSGQAASSHEQARSSA-----GERHGSRHQLQSADSSRHSGTGHGQASS 732
K+G + SS + +S E+ +A + G Q+ +A + G A +
Sbjct: 330 TKAGKPEEDSESSSEESSDSEEETPAAKALLQAKASGKTSQVGAASAPAKESPRKGAAPA 389
Query: 733 AVRDSGH---RGSSGSQATDSEGHSEDSDTQSVSGHGQAGHHQQSHQESARDRSGERSRR 789
+G + +G + DS+ SE+SD++ QA ++ Q A + S R
Sbjct: 390 PPGKTGPAVAKAQAGKREEDSQSSSEESDSEE-EAPAQAKPSGKAPQVRAASAPAKESPR 448
Query: 790 SGSFLYQVSTHKQSESSHGWTGPSTG-VRQGSHHEQARDNSRHSASQDGQDTIRGHPGSS 848
G+ + + TGP+ V+ G E +R +S S S
Sbjct: 449 KGA----------APAPPRKTGPAAAQVQVGKQEEDSRSSSEESDSDREALAAMNAAQVK 498
Query: 849 RRGRQGSHHEQSVDRSGHSGSHHSHTTSQGRSDASRGQSGSRSASRTTRNEEQSRDGSRH 908
G+ S G G +G G+ G + S E+ +
Sbjct: 499 PLGKSPQVKPASTMGMGPLG--------KGAGPVPPGKVGPATPSAQVGKWEEDSE---- 546
Query: 909 SGSRHHEASSHADISRHSQAGQGQSEGSRTSRRQGSSVSQDSDSEGHSEDSERWSGSASR 968
S S SS ++ Q +S G+ + SS ++ G +
Sbjct: 547 SSSEESSDSSDGEVPTAVAPAQEKSLGNILQAKPTSSPAK---------------GPPQK 591
Query: 969 NHRGSAQEQSRHGSRHPRSHHEDRAGHGHSADSSRQSGTPHAETSSGGQAASSHEQARSS 1028
+ Q ++ + S E S+DS+ P A T++ + A Q ++
Sbjct: 592 AGPVAVQVKAEKPMDNSESSEE-------SSDSADSEEAPAAMTAAQAKPALKIPQTKAC 644
Query: 1029 PGERHGSRHQQSADSSRHSGIPRR-------QASSAVRDSGHWGSSGSQASDSEGHSEES 1081
P + + + + A + PR+ SS G + +S E SEE
Sbjct: 645 PKKTNTTASAKVAPVRVGTQAPRKAGTATSPAGSSPAVAGGTQRPAEDSSSSEESDSEEE 704
Query: 1082 DTQSVSGHGQDGPHQQSHQESARD----WSGGRS------GRSGSFIYQVSTHEQSESAH 1131
T GQ + Q A S G+ G++G + QV +Q +S
Sbjct: 705 KTGLAVTVGQAKSVGKGLQVKAASVPVKGSLGQGTAPVLPGKTGPTVTQVKAEKQEDSES 764
Query: 1132 GRTRTSTGRRQGSHHE--------QARDSSRHSASQEGQDTIRAHPGSRRGGRQGSHHEQ 1183
+ + S + QA+ + + + + TI A Q
Sbjct: 765 SEEESDSEEAAASPAQVKTSVKKTQAKANPAAARAPSAKGTISAPGKVVTAAAQAKQRSP 824
Query: 1184 SVDRSGHSGSHHSHTTSQG-RSDASHGQSGSRSASRQTRKDKQSGDGSRHSGSRHHEAAS 1242
S + +S ++G S S G++ + +A QT ++ SG S S EA +
Sbjct: 825 SKVKPPVRNPQNSTVLARGPASVPSVGKAVATAAQAQTGPEEDSGSSEEESDS-EEEAET 883
Query: 1243 WADSSRHSQVGQEQS--SGSRTSRHQGSSVSQDSDSERHSDDSERLSGSASRNHHGSSRE 1300
A + Q ++ + ++ S +G++ + + + + ++ GSS E
Sbjct: 884 LAQVKPSGKTHQIRAALAPAKESPRKGAAPTPPGKT------GPSAAQAGKQDDSGSSSE 937
Query: 1301 QSRDGSRHPG-------------FHQEDRASHGHSAD--SSRQSGTHHTESSSHGQAVSS 1345
+S P F +R+ G +A ++ + T +S A SS
Sbjct: 938 ESDSDGEAPAAVTSAQVIKPPLIFVDPNRSPAGPAATPAQAQAASTPRKARASESTARSS 997
Query: 1346 HEQARS----------SPGERHG-----SRHQQSADSSRHSGIGHRQASSAVRDSGHRGS 1390
++ +PG R + H + A + +G + SS + D +
Sbjct: 998 SSESEDEDVIPATQCLTPGIRTNVVTMPTAHPRIAPKASMAGASSSKESSRISDGKKQEG 1057
Query: 1391 SGSQVTNSEGHSEDSDTQSVSAHGQAGPH---------QQSHKESARGQSGESSGRSRSF 1441
+QV ++ G + QS S + QQ+ K E S S S
Sbjct: 1058 PATQVDSAVGTLPATSPQSTSVQAKGTNKLRKPKLPEVQQATKAPESSDDSEDSSDSSSG 1117
Query: 1442 LYQVSSHEQ-SESTHGQTAPSTGGRQGSRHEQARNSSRHSASQDGQDTIRGH--PGSSRG 1498
+ Q ++S H P+ + E A SS Q + G+ PG +
Sbjct: 1118 SEEDGEGPQGAKSAHTLVGPTPSRTETLVEETAAESSEDDVVAPSQSLLSGYMTPGLTPA 1177
Query: 1499 GRQGSYHEQSVDRS-GHSGYHHSHTTPQGRSDASHGQSGPRSASRQTRNEEQSGDGSRHS 1557
Q S +D S S + P G+ +A Q+ + + E SG + S
Sbjct: 1178 NSQASKATPKLDSSPSVSSTLAAKDDPDGKQEAKPQQAAGMLSPKTGGKEAASGTTPQKS 1237
Query: 1558 -----GSRHHEPSTRAGSSRHSQVGQGESAGSKTSRRQGSSV-------SQDRDS--EGH 1603
G+ + + ST A S +Q G+ ++ Q S V Q+R +
Sbjct: 1238 RKPKKGAGNPQASTLALQSNITQCLLGQPWPLNEAQVQASVVKVLTELLEQERKKVVDTT 1297
Query: 1604 SEDSERRSESASRNHYGSAREQSRHGSRNPRSHQEDRASHGHSAESSRQSGTRHAETSSG 1663
E S + ES R G + +R PRS ++ + G E+S T+S
Sbjct: 1298 KESSRKGWESRKRKLSG-----DQPAARTPRSKKKKKLGAGEGGEAS--VSPEKTSTTSK 1350
Query: 1664 GQA----ASSQEQARSSPGE--RHGSRHQQSADSSTDSGTGRRQDSSVVGDSGNRGSSGS 1717
G+A AS + + G G++ + + GT D S + S
Sbjct: 1351 GKAKRDKASGDVKEKKGKGSLGSQGAKDEPEEELQKGMGTVEGGDQSNPKSKKEKKKSDK 1410
Query: 1718 QASDSEGHSEESDTQSVSAHGQAGPHQQSHQESTR 1752
+ D E ++ + S P Q+ ++ +
Sbjct: 1411 RKKDKEKKEKKKKAKKASTKDSESPSQKKKKKKKK 1445
Score = 74.7 bits (182), Expect = 2e-12
Identities = 282/1517 (18%), Positives = 505/1517 (33%), Gaps = 228/1517 (15%)
Query: 1960 HHEDRAGHGHSA-DSSRQSG---------------TRHTESSSRGQAASSHEQARSSAGE 2003
HH RAG+ +A + QSG T ++S G+ + E A A +
Sbjct: 16 HHLLRAGYVRAAREVKEQSGQKCFLAQPVTLLDIYTHWQQTSELGRKRKAEEDAALQAKK 75
Query: 2004 RHGSHHQLQSADSSRHSGIGHGQASSAVRD--SGHRGYSGSQASDSEGHSEDSDTQSVSA 2061
S + +++SS + + A S + G+ S ++T+
Sbjct: 76 TRVSD-PISTSESSEEEEEAEAETAKATPRLASTNSSVLGADLPSSMKEKAKAETEKAGK 134
Query: 2062 QGKAGPHQQSHKESARGQSGESSGRSGSFLYQVSTHEQSESTHGQSAPSTGGRQGS-HYD 2120
G + PH + K A SG+S +S + ++E A + G
Sbjct: 135 TGNSMPHPATGKTVANLLSGKSPRKSAEPSANTTLVSETEEEGSVPAFGAAAKPGMVSAG 194
Query: 2121 QAQDSSRHSASQEGQDTIRGHPGPSRGGRQGSH---QEQSVDRSGHSGSHHSHTTSQGRS 2177
QA SS ++S + + G P + S +E ++ + T Q +
Sbjct: 195 QADSSSEDTSSSSDETDVEGKPSVKPAQVKASSVSTKESPARKAAPAPGKVGDVTPQVKG 254
Query: 2178 DASRGQSGSRSASRKTYDKEQSGDGSRHSGSHHHEASSWADSSRHSLVGQGQSSGPRTSR 2237
G+ +++ E+ + S EA + S Q ++S
Sbjct: 255 -------GALPPAKRAKKPEEESESSEEGSESEEEAPAGTRS-------QVKASEKILQV 300
Query: 2238 PRGSSVSQDSDSEGHSEDSERRSGS-ASRNHHGSAQEQSRDGSRHPRSHHEDRAGHGHSA 2296
S+ ++ + +G + ++G+ AS+ G +E S S E+ +A
Sbjct: 301 RAASAPAKGTPGKGATPAPPGKAGAVASQTKAGKPEEDSESSSEESSDSEEETP----AA 356
Query: 2297 ESSRQSGTHHAENSSGGQAASSHEQARSSAGERHGSHHQQSADSSRHSGIGHGQASSAVR 2356
++ Q+ + G +A + E R A G+ AV
Sbjct: 357 KALLQAKASGKTSQVGAASAPAKESPRKGAAPAPP-----------------GKTGPAVA 399
Query: 2357 DSGHRGSSGSQASDSEGHSEDSDTQSVSAHGQAGPHQQSHQESTRGRSAGRSGRSGSFLY 2416
+ +G + DS+ SE+SD++ A QA P ++ Q A S R G+
Sbjct: 400 ----KAQAGKREEDSQSSSEESDSEE-EAPAQAKPSGKAPQVRAASAPAKESPRKGA--- 451
Query: 2417 QVSTHEQSESAHGRTGTSTGGRQ-GSHHKQARDSSRHSTSQEGQDTIHGHPGSSSGGRQG 2475
+ + +TG + Q G + +R SS S S G+
Sbjct: 452 -------APAPPRKTGPAAAQVQVGKQEEDSRSSSEESDSDREALAAMNAAQVKPLGKSP 504
Query: 2476 SHYEQLVDRSGHSGSHHSHTTSQGRSDASHGHSGSRSASRQTRNDEQSGDGSRHSGSRHH 2535
G G +G G G + S Q E+ + S
Sbjct: 505 QVKPASTMGMGPLG--------KGAGPVPPGKVGPATPSAQVGKWEEDSESSSE------ 550
Query: 2536 EASSRADSSGHSQVGQGQSEGPRTSRNWGSSFSQDSDSQGHSEDSERWSGSASRNHHGSA 2595
E+S +D + V Q + S G+ ++ S A +
Sbjct: 551 ESSDSSDGEVPTAVAPAQEK-----------------SLGNILQAKPTSSPAKGPPQKAG 593
Query: 2596 QEQLRDGSRHPRSHQEDRAGHGHSADSSRQSGTRHTQTSSGGQAASSHEQARSSAGERHG 2655
++ + P + E SADS T++ + A Q ++ + +
Sbjct: 594 PVAVQVKAEKPMDNSESSEESSDSADSEEAPAA---MTAAQAKPALKIPQTKACPKKTNT 650
Query: 2656 SHHQQSA------DSSRHSGIGHGQASS--AVRDSGHRGYSGSQASDNEGHSEDSDTQSV 2707
+ + A + R +G A S AV R S +S+ E SE+ T
Sbjct: 651 TASAKVAPVRVGTQAPRKAGTATSPAGSSPAVAGGTQRPAEDSSSSE-ESDSEEEKTGLA 709
Query: 2708 SAHGQAGSHQQSHQESA----------RGRSGETSGHSGSFLYQV---------STHEQS 2748
GQA S + Q A +G + G +G + QV S+ E+S
Sbjct: 710 VTVGQAKSVGKGLQVKAASVPVKGSLGQGTAPVLPGKTGPTVTQVKAEKQEDSESSEEES 769
Query: 2749 ESSHGWTGPSTRGRQGSRHEQAQDSSRHSASQDGQDTIRGHPGSSRGGRQGYHHEHSVDS 2808
+S P+ + + + QA+ + + + + TI Q S
Sbjct: 770 DSEEAAASPA-QVKTSVKKTQAKANPAAARAPSAKGTISAPGKVVTAAAQAKQRSPSKVK 828
Query: 2809 SGHSGSHHSHTTSQGRSDA-SRGQSGSRSASRTTRNEEQSGDGSRHSGSRHHEASTHADI 2867
+S ++G + S G++ + +A T EE SG S S EA T A +
Sbjct: 829 PPVRNPQNSTVLARGPASVPSVGKAVATAAQAQTGPEEDSGSSEEESDSEE-EAETLAQV 887
Query: 2868 --SRHSQAVQGQSEGSRRSRRQGSS------VSQDSDSEGHSEDSERWSGSASRNHHGSA 2919
S + ++ ++ S R+G++ + G +DS S + + A
Sbjct: 888 KPSGKTHQIRAALAPAKESPRKGAAPTPPGKTGPSAAQAGKQDDSGSSSEESDSDGEAPA 947
Query: 2920 QEQLRDGSRHPRSHQEDRAGHGHSADSSRQSGTRHTQTSSGGQAASSHEQARSSAGERHG 2979
+ P + A + Q+ T +A +S ARSS+ E
Sbjct: 948 AVTSAQVIKPPLIFVDPNRSPAGPAATPAQAQAASTPR----KARASESTARSSSSESED 1003
Query: 2980 SH----------------------HQQSADSSRHSGIGHGQASSAVRDSGHRGYSGSQAS 3017
H + A + +G + SS + D + +Q
Sbjct: 1004 EDVIPATQCLTPGIRTNVVTMPTAHPRIAPKASMAGASSSKESSRISDGKKQEGPATQVD 1063
Query: 3018 DNEGHSEDSDTQSVSAHGQAGSH---------QQSHQESARGRSGETSGHSGSFLYQVST 3068
G + QS S + + QQ+ + E S S S +
Sbjct: 1064 SAVGTLPATSPQSTSVQAKGTNKLRKPKLPEVQQATKAPESSDDSEDSSDSSSGSEEDGE 1123
Query: 3069 HEQ-SESSHGWTGPSTRGRQGSRHEQAQDSSRHSASQYGQDTIRGH--PGSSRGGRQGYH 3125
Q ++S+H GP+ + E A +SS Q + G+ PG + Q
Sbjct: 1124 GPQGAKSAHTLVGPTPSRTETLVEETAAESSEDDVVAPSQSLLSGYMTPGLTPANSQASK 1183
Query: 3126 HEHSVDSSGH-SGSHHSHTTSQGRSDASRGQSGSRSASRTTRNEEQSGDSSRHSV----- 3179
+DSS S + + G+ +A Q+ + +T E SG + + S
Sbjct: 1184 ATPKLDSSPSVSSTLAAKDDPDGKQEAKPQQAAGMLSPKTGGKEAASGTTPQKSRKPKKG 1243
Query: 3180 SRHHEASTHADISRHSQAVQGQSEGSRRSRRQGSSVSQDSDSEGHSEDSERWSGSASRNH 3239
+ + +AST A S +Q + GQ ++ Q S V ++
Sbjct: 1244 AGNPQASTLALQSNITQCLLGQPWPLNEAQVQASVVKVLTE--------------LLEQE 1289
Query: 3240 RGSVQEQSRHGSRHP-RSHHEDRAGHGHSADRSRQSGTRHAETSSGGQAASSHEQARSSP 3298
R V + ++ SR S +G +A R + GG+A+ S E+ ++
Sbjct: 1290 RKKVVDTTKESSRKGWESRKRKLSGDQPAARTPRSKKKKKLGAGEGGEASVSPEKTSTTS 1349
Query: 3299 GERHGSRHQQSADSSRHSGIPRGQASSAVRDSRHWGSSGSQASDSEGHSEESDTQSVSGH 3358
+ R +AS V++ + GS GSQ G +E + + G
Sbjct: 1350 KGK----------------AKRDKASGDVKEKKGKGSLGSQ-----GAKDEPEEELQKGM 1388
Query: 3359 GQAGPHQQSHQESARDR 3375
G QS+ +S +++
Sbjct: 1389 GTVEGGDQSNPKSKKEK 1405
Score = 65.1 bits (157), Expect = 1e-09
Identities = 241/1245 (19%), Positives = 419/1245 (33%), Gaps = 131/1245 (10%)
Query: 1197 HTTSQGRSDASHGQSGSRSASRQTRKDKQSGDGSRHSGSRHHEAASWAD--------SSR 1248
+T Q S+ + A+ Q +K + S S S E A S+
Sbjct: 50 YTHWQQTSELGRKRKAEEDAALQAKKTRVSDPISTSESSEEEEEAEAETAKATPRLASTN 109
Query: 1249 HSQVGQE-QSSGSRTSRHQGSSVSQDSDSERHSDDSERLSGSASRNHHGSSREQSRDGSR 1307
S +G + SS ++ + + +S H + ++ S S E S + +
Sbjct: 110 SSVLGADLPSSMKEKAKAETEKAGKTGNSMPHPATGKTVANLLSGKSPRKSAEPSANTTL 169
Query: 1308 HPGFHQEDRASHGHSADSSRQSGTHHTESSSHGQAVSSHE-QARSSPGERHGSRHQQSAD 1366
+E +A +SSS + SS E P + S
Sbjct: 170 VSETEEEGSVPAFGAAAKPGMVSAGQADSSSEDTSSSSDETDVEGKPSVKPAQVKASSVS 229
Query: 1367 SSRHSGIGHRQASSAVRDSGHRGSSGSQVTNSEGHSEDSDTQSVSAHGQAGPHQQSHKES 1426
+ A V D + G+ + +++S S G +S +E+
Sbjct: 230 TKESPARKAAPAPGKVGDVTPQVKGGALPPAKRAKKPEEESES-SEEGS-----ESEEEA 283
Query: 1427 ARGQSGESSGRSRSFLYQVSSHEQSESTHGQTA-PSTGGRQGSRHEQAR----NSSRHSA 1481
G + S L ++ ++ T G+ A P+ G+ G+ Q + S+
Sbjct: 284 PAGTRSQVKA-SEKILQVRAASAPAKGTPGKGATPAPPGKAGAVASQTKAGKPEEDSESS 342
Query: 1482 SQDGQDTIRGHPGSSRGGRQGSYHEQSVDRSGHSGYHHSHTTPQGRSDASHGQSGPRSAS 1541
S++ D+ P + + + + S + G + + +G + A G++GP A
Sbjct: 343 SEESSDSEEETPAAKALLQAKASGKTS--QVGAASAPAKESPRKGAAPAPPGKTGPAVAK 400
Query: 1542 RQT-RNEEQSGDGSRHSGSRHHEPSTRAGSSRHSQVGQGESAGSKTSRRQGSSVS----- 1595
Q + EE S S S S P+ S + QV + SA +K S R+G++ +
Sbjct: 401 AQAGKREEDSQSSSEESDSEEEAPAQAKPSGKAPQV-RAASAPAKESPRKGAAPAPPRKT 459
Query: 1596 -----------QDRDSEGHSEDSERRSESASRNHYGSAREQSRHGSRNPRSHQE-DRASH 1643
Q+ DS SE+S+ E+ + + + + P S
Sbjct: 460 GPAAAQVQVGKQEEDSRSSSEESDSDREALAAMNAAQVKPLGKSPQVKPASTMGMGPLGK 519
Query: 1644 GHSAESSRQSGTRHAETSSG----GQAASSQEQARSSPGE-----------RHGSRHQQS 1688
G + G G +SS+E + SS GE G+ Q
Sbjct: 520 GAGPVPPGKVGPATPSAQVGKWEEDSESSSEESSDSSDGEVPTAVAPAQEKSLGNILQAK 579
Query: 1689 ADSSTDSGTGRRQDSSVVGDSGNRGSSGSQASDSEGHSEESD-TQSVSAHGQAGPHQQSH 1747
SS G ++ V + S++S+ S +S+ + QA P +
Sbjct: 580 PTSSPAKGPPQKAGPVAVQVKAEKPMDNSESSEESSDSADSEEAPAAMTAAQAKPALKIP 639
Query: 1748 QESTRGQSGERSGRSGSFLYQVSTHEQSE-----SAHGRTGPSTGGRQRSRHEQARDSSR 1802
Q + + + +V T + S G + GG QR + + SS
Sbjct: 640 QTKACPKKTNTTASAKVAPVRVGTQAPRKAGTATSPAGSSPAVAGGTQRPAEDSS--SSE 697
Query: 1803 HSASQEGQDTIRGHPGSSRGGRQGSHYEQ-SVDSSGHSGSHHSHTTSQERSDVSRGQSGS 1861
S S+E + + G ++ +G + SV G G Q + V G++G
Sbjct: 698 ESDSEEEKTGLAVTVGQAKSVGKGLQVKAASVPVKGSLG--------QGTAPVLPGKTGP 749
Query: 1862 RSVSRQTRNEKQSGDGSRHSGSRHHEASSRADSSRHSQVGQGQSSGPRTSRNQGS--SVS 1919
Q + EKQ S S EA++ + S + P +R + ++S
Sbjct: 750 TVT--QVKAEKQEDSESSEEESDSEEAAASPAQVKTSVKKTQAKANPAAARAPSAKGTIS 807
Query: 1920 QDSDSQGHSEDSERWSGSASRNHLGSAWEQSRDGSRHPGSHHEDRAGHGHSADSSRQSGT 1979
+ +++ S S + + + + S +R P S G + + Q+G
Sbjct: 808 APGKVVTAAAQAKQRSPSKVKPPVRNP-QNSTVLARGPAS--VPSVGKAVATAAQAQTGP 864
Query: 1980 RHTESSSRGQAASSHEQARSSAGERHGSHHQLQSADSSRHSGIGHGQASSAVRDSGHRGY 2039
SS ++ S E + + G HQ+++A + G A + +G
Sbjct: 865 EEDSGSSEEESDSEEEAETLAQVKPSGKTHQIRAALAPAKESPRKGAAPTPPGKTGPSAA 924
Query: 2040 SGSQASDSEGHSEDSDTQS------VSAQ-------------GKAGP-----HQQSHKES 2075
+ DS SE+SD+ SAQ AGP Q+
Sbjct: 925 QAGKQDDSGSSSEESDSDGEAPAAVTSAQVIKPPLIFVDPNRSPAGPAATPAQAQAASTP 984
Query: 2076 ARGQSGESSGRSGSFLYQVSTHEQSESTHGQSAPSTGGRQG-SHYDQAQDSSRHSASQEG 2134
+ ++ ES+ RS S S E + + G R A AS G
Sbjct: 985 RKARASESTARSSS-----SESEDEDVIPATQCLTPGIRTNVVTMPTAHPRIAPKASMAG 1039
Query: 2135 QDTIRGHPGPSRGGRQGSHQEQSVD--------RSGHSGSHHSHTTSQGRSDASRGQSGS 2186
+ + S G +Q Q VD S S S + T++ R +
Sbjct: 1040 ASSSKESSRISDGKKQEGPATQ-VDSAVGTLPATSPQSTSVQAKGTNKLRKPKLPEVQQA 1098
Query: 2187 RSASRKTYDKEQSGDGSRHSGSHHHEASSWADSSRHSLVGQGQSSGPRTSRPRGSSVSQD 2246
A + D E S D S SGS S H+LVG S RT + ++
Sbjct: 1099 TKAPESSDDSEDSSDSS--SGSEEDGEGPQGAKSAHTLVGPTPS---RTETLVEETAAES 1153
Query: 2247 SDSEGHSEDSERRSGSAS-----RNHHGSAQEQSRDGSRHPRSHHEDRAGHGHSAESSRQ 2301
S+ + + SG + N S D S S + E+ Q
Sbjct: 1154 SEDDVVAPSQSLLSGYMTPGLTPANSQASKATPKLDSSPSVSSTLAAKDDPDGKQEAKPQ 1213
Query: 2302 SGTHHAENSSGGQAASSHEQARSSAGERHGSHHQQSADSSRHSGI 2346
+GG+ A+S + S + G+ + Q++ + S I
Sbjct: 1214 QAAGMLSPKTGGKEAASGTTPQKSRKPKKGAGNPQASTLALQSNI 1258
Score = 60.5 bits (145), Expect = 3e-08
Identities = 232/1323 (17%), Positives = 447/1323 (33%), Gaps = 119/1323 (8%)
Query: 345 SHGHSADSSRQSGTRHAETSSRGQTASSHEQARSSPGERHGSGHQQSADSSRHSATGRGQ 404
S G + SS + + ET G+ + Q ++S S +++A + Q
Sbjct: 192 SAGQADSSSEDTSSSSDETDVEGKPSVKPAQVKASSVSTKESPARKAAPAPGKVGDVTPQ 251
Query: 405 ASSAVSDRGHRGSSGSQASDSEGHSENSDTQSVSGHGKAGLRQQSHQESTRGRSGERSGR 464
R + S+S S+ ++ +G ++ ++ R S G
Sbjct: 252 VKGGALPPAKRAKKPEEESESSEEGSESEEEAPAGT-RSQVKASEKILQVRAASAPAKGT 310
Query: 465 SGSSLYQVSTHEQPDSAHGRTGTSTGGR----QGSHHEQARDSSRHSASQEGQDTIRGHP 520
G +T P A + G+ S E++ DS + + + +
Sbjct: 311 PGKG----ATPAPPGKAGAVASQTKAGKPEEDSESSSEESSDSEEETPAAKALLQAKASG 366
Query: 521 GSSRGGRQGSHHEQSVNRSGHSGSHHSHTTSQGRSDASHGQSGSRSASRQTRNEEQSGDG 580
+S+ G + ++S + + ++ A + S+S+S ++ +EE++
Sbjct: 367 KTSQVGAASAPAKESPRKGAAPAPPGKTGPAVAKAQAGKREEDSQSSSEESDSEEEAPAQ 426
Query: 581 TRHSGSRHHEASSQADSSRHSQVGQG----QSSGPRTSRNQGSSVSQDSDSQGHSEDSER 636
+ SG ++ A + + G + +GP ++ Q +DS S DS+R
Sbjct: 427 AKPSGKAPQVRAASAPAKESPRKGAAPAPPRKTGPAAAQVQVGKQEEDSRSSSEESDSDR 486
Query: 637 ---WSGSASRNHHGSAQEQSRDGSRHPRSHHEDRAGH------GHSADSSRKSGTRHTQN 687
+ +A++ Q + S AG G + S++
Sbjct: 487 EALAAMNAAQVKPLGKSPQVKPASTMGMGPLGKGAGPVPPGKVGPATPSAQVGKWEEDSE 546
Query: 688 SSSGQAASSHE----QARSSAGERHGSRHQLQSADSSRHSGTGHGQASSAVRDSGHRGSS 743
SSS +++ S + A + A E+ SS G AV+ +
Sbjct: 547 SSSEESSDSSDGEVPTAVAPAQEKSLGNILQAKPTSSPAKGPPQKAGPVAVQVKAEKPMD 606
Query: 744 GSQATDSEGHSEDS-DTQSVSGHGQAGHHQQSHQESARDRSGERSRRSGSFLYQVSTH-- 800
S++++ S DS + + QA + Q A + + + +V T
Sbjct: 607 NSESSEESSDSADSEEAPAAMTAAQAKPALKIPQTKACPKKTNTTASAKVAPVRVGTQAP 666
Query: 801 KQSESSHGWTGPSTGVRQGSHH-EQARDNSRHSASQDGQDTIRGHPGSSRRGRQGSH-HE 858
+++ ++ G S V G+ + +S S S++ + + G ++ +G
Sbjct: 667 RKAGTATSPAGSSPAVAGGTQRPAEDSSSSEESDSEEEKTGLAVTVGQAKSVGKGLQVKA 726
Query: 859 QSVDRSGHSGSHHSHTTSQGRSDASRGQSGSRSASRTTRNEEQSRDGSRHSGSRHHEAS- 917
SV G G QG + G++G +E S S S AS
Sbjct: 727 ASVPVKGSLG--------QGTAPVLPGKTGPTVTQVKAEKQEDSESSEEESDSEEAAASP 778
Query: 918 SHADISRHSQAGQGQSEGSRTSRRQGSSVSQDSDSEGHSEDSERWSGSASRNHRGSAQEQ 977
+ S + +R +G+ + ++ +R R +
Sbjct: 779 AQVKTSVKKTQAKANPAAARAPSAKGTISAPGKVVTAAAQAKQRSPSKVKPPVRN--PQN 836
Query: 978 SRHGSRHPRSHHEDRAGHGHSADSSRQSGTPHAETSSGGQAASSHEQARS-SPGERHGSR 1036
S +R P S G + + Q+G P ++ S + + S E+A + + + G
Sbjct: 837 STVLARGPAS--VPSVGKAVATAAQAQTG-PEEDSGSSEEESDSEEEAETLAQVKPSGKT 893
Query: 1037 HQQSADSSRHSGIPRRQASSAVRDSGHWGSSGSQA---SDSEGHSEESDTQSVSGHGQDG 1093
HQ A + PR+ A A G G S +QA DS SEESD+ +
Sbjct: 894 HQIRAALAPAKESPRKGA--APTPPGKTGPSAAQAGKQDDSGSSSEESDSDGEAPAAVTS 951
Query: 1094 PHQQSHQESARDWSGGRSGRSGSFIYQVSTHEQSESAHGRTRTSTGRRQGSHHEQARDSS 1153
D + +G +T Q+++A ST R+ + AR SS
Sbjct: 952 AQVIKPPLIFVDPNRSPAG-------PAATPAQAQAA------STPRKARASESTARSSS 998
Query: 1154 RHSASQEGQDTIRA----HPGSRRG-GRQGSHHEQSVDRSGHSGSHHSHTTSQGRSDASH 1208
S E +D I A PG R + H + ++ +G+ S ++S
Sbjct: 999 SES---EDEDVIPATQCLTPGIRTNVVTMPTAHPRIAPKASMAGASSS-------KESSR 1048
Query: 1209 GQSGSRSASRQTRKDKQSGDGSRHSGSRHHEAASWADSSRHSQVGQ--------EQSSGS 1260
G + T+ D G S A + R ++ + E S S
Sbjct: 1049 ISDGKKQEGPATQVDSAVGTLPATSPQSTSVQAKGTNKLRKPKLPEVQQATKAPESSDDS 1108
Query: 1261 RTSRHQGSSVSQDSDSERHSDDSERLSGSASRNHHGSSREQSRDGSRHPGFHQEDRASHG 1320
S S +D + + + + L G E + + S G
Sbjct: 1109 EDSSDSSSGSEEDGEGPQGAKSAHTLVGPTPSRTETLVEETAAESSEDDVVAPSQSLLSG 1168
Query: 1321 H------SADSSRQSGTHHTESSSHGQAVSSHEQARSSPGERHGSRHQQSADSSRHSGIG 1374
+ A+S T +SS +VSS A+ P + ++ QQ+A G
Sbjct: 1169 YMTPGLTPANSQASKATPKLDSS---PSVSSTLAAKDDPDGKQEAKPQQAAGMLSPKTGG 1225
Query: 1375 HRQASSAVRDSGHRGSSGSQVTNSEGHSEDSD-TQSVSAHGQAGPHQQSH-KESARGQSG 1432
AS + G+ + + S+ TQ + GQ P ++ + S
Sbjct: 1226 KEAASGTTPQKSRKPKKGAGNPQASTLALQSNITQCLL--GQPWPLNEAQVQASVVKVLT 1283
Query: 1433 ESSGRSRSFLYQVSSHEQSESTHGQTAPSTGGRQGSRHEQARNSSRHSASQDGQDTIRGH 1492
E + R + + + + +G + +R +++ + A + G+ ++
Sbjct: 1284 ELLEQERKKVVDTTKESSRKGWESRKRKLSGDQPAARTPRSKKKKKLGAGEGGEASVSPE 1343
Query: 1493 PGSSRGGRQGSYHEQSVDRSGHSGYHHSHTTPQGRSDASHGQSGPRSASRQTRNEEQSGD 1552
S+ + + S D G G G + A + E Q G
Sbjct: 1344 KTSTTSKGKAKRDKASGDVKEKKG---------------KGSLGSQGAKDEPEEELQKGM 1388
Query: 1553 GSRHSGSRHHEPSTRAGSSRHSQVGQGESAGSKTSRRQGSSVSQDRDSEGHSEDSERRSE 1612
G+ G + + S + + E K ++ S+ +DSE S+ +++ +
Sbjct: 1389 GTVEGGDQSNPKSKKEKKKSDKRKKDKEKKEKKKKAKKAST----KDSESPSQKKKKKKK 1444
Query: 1613 SAS 1615
+
Sbjct: 1445 KTA 1447
Score = 57.8 bits (138), Expect = 2e-07
Identities = 230/1240 (18%), Positives = 415/1240 (33%), Gaps = 176/1240 (14%)
Query: 2828 SRGQSGSRSASRTTRNEEQSGDGS---RHSGSRHHEASTHADISRHSQAVQGQ------- 2877
S GQ+ S S ++ ++E +G + + + ST +R + G+
Sbjct: 192 SAGQADSSSEDTSSSSDETDVEGKPSVKPAQVKASSVSTKESPARKAAPAPGKVGDVTPQ 251
Query: 2878 -SEGSRRSRRQGSSVSQDSDSEGHSEDSERWSGSASRNHHGSAQEQLRDGSRHPRSHQED 2936
G+ ++ ++S+S +SE + + +R+ ++++ L+ R + +
Sbjct: 252 VKGGALPPAKRAKKPEEESESSEEGSESEEEAPAGTRSQVKASEKILQ--VRAASAPAKG 309
Query: 2937 RAGHGHSADSSRQSGTRHTQTSSGGQAASSHEQARSSAGERHGSHHQQSADSSRHSGIGH 2996
G G + ++G +QT +G S + S+ + ++ ++ SG
Sbjct: 310 TPGKGATPAPPGKAGAVASQTKAGKPEEDSESSSEESSDSEEETPAAKALLQAKASGKTS 369
Query: 2997 --GQASSAVRDSGHRG----------------YSGSQASDNEGHSEDSDTQSVSAHGQAG 3038
G AS+ ++S +G +G + D++ SE+SD++ A QA
Sbjct: 370 QVGAASAPAKESPRKGAAPAPPGKTGPAVAKAQAGKREEDSQSSSEESDSEE-EAPAQAK 428
Query: 3039 SHQQSHQESARGRSGETSGHSGSFLYQVSTHEQSESSHGWTGPSTRGRQ-GSRHEQAQDS 3097
++ Q A + S G+ + + TGP+ Q G + E ++ S
Sbjct: 429 PSGKAPQVRAASAPAKESPRKGA----------APAPPRKTGPAAAQVQVGKQEEDSRSS 478
Query: 3098 SRHSASQYGQDTIRGHPGSSRGGRQGYHHEHSVDSSGHSGSHHSHTTSQGRSDASRGQSG 3157
S S S G+ S G G +G G+ G
Sbjct: 479 SEESDSDREALAAMNAAQVKPLGKSPQVKPASTMGMGPLG--------KGAGPVPPGKVG 530
Query: 3158 SRSASRTTRNEEQSGDSSRHSVSRHHEASTHADISRHSQAVQGQSEGSRRSRRQGSSVSQ 3217
+ S E+ +SS S S+ ++ Q +S G+ + SS ++
Sbjct: 531 PATPSAQVGKWEEDSESS----SEESSDSSDGEVPTAVAPAQEKSLGNILQAKPTSSPAK 586
Query: 3218 DSDSEGHSEDSERWSGSASRNHRGSVQEQSRHGSRHPRSHHEDRAGHGHSADRSRQSGTR 3277
+ G V Q + + P + E SAD
Sbjct: 587 GPPQKA-----------------GPVAVQVK--AEKPMDNSESSEESSDSADSEEAPA-- 625
Query: 3278 HAETSSGGQAASSHEQARSSPGERHGSRHQQSADSSRHSGIPR--GQASSAVRDSRHWGS 3335
A T++ + A Q ++ P + + + + A + PR G A+S S
Sbjct: 626 -AMTAAQAKPALKIPQTKACPKKTNTTASAKVAPVRVGTQAPRKAGTATSPAGSSPAVAG 684
Query: 3336 SGSQASDSEGHSEESDTQSVSGH-----GQAGPHQQSHQESARD----RSGGRS------ 3380
+ ++ SEESD++ GQA + Q A S G+
Sbjct: 685 GTQRPAEDSSSSEESDSEEEKTGLAVTVGQAKSVGKGLQVKAASVPVKGSLGQGTAPVLP 744
Query: 3381 GRSGSFLYQVSTHEQSESAHGRTRTSTGRRQGSHHE--------QARDSSRHSASQEGQD 3432
G++G + QV +Q +S + + S + QA+ + + + +
Sbjct: 745 GKTGPTVTQVKAEKQEDSESSEEESDSEEAAASPAQVKTSVKKTQAKANPAAARAPSAKG 804
Query: 3433 TIRGHPGSSRRGRQGSHYEQSVDRSGHSGSHHSHTTSQGRSDA-SRGQSGSRSASRQTRN 3491
TI Q S + +S ++G + S G++ + +A QT
Sbjct: 805 TISAPGKVVTAAAQAKQRSPSKVKPPVRNPQNSTVLARGPASVPSVGKAVATAAQAQTGP 864
Query: 3492 DEQSGDGSRHSWSHHHEASTQADSSRHSQSGQ------------GQSAGPRTSRNQGSSV 3539
+E SG S S EA T A ++ Q + A P G S
Sbjct: 865 EEDSGSSEEESDSEE-EAETLAQVKPSGKTHQIRAALAPAKESPRKGAAPTPPGKTGPSA 923
Query: 3540 SQDSDSQGHSEDSERWSGSASRNHRGSAQEQSRDGSRHPTSHHE-DRAGHGHSAESSRQS 3598
+Q G +DS S + + A S + P + +R+ G +A ++
Sbjct: 924 AQ----AGKQDDSGSSSEESDSDGEAPAAVTSAQVIKPPLIFVDPNRSPAGPAATPAQAQ 979
Query: 3599 GTHHAENSSGGQAASSHEQARSSAGERHGSH----------------------HQQSADS 3636
S+ +A +S ARSS+ E H + A
Sbjct: 980 AA-----STPRKARASESTARSSSSESEDEDVIPATQCLTPGIRTNVVTMPTAHPRIAPK 1034
Query: 3637 SRHSGIGHGQASSAVRDSGHRGSSGSQASDSEGHSEDSDTQSVSAHGQAG-----PHQQS 3691
+ +G + SS + D + +Q + G + QS S + P
Sbjct: 1035 ASMAGASSSKESSRISDGKKQEGPATQVDSAVGTLPATSPQSTSVQAKGTNKLRKPKLPE 1094
Query: 3692 HQESTRGRSAGRSGRSGSFLYQVSTHEQ-----SESAHGRAGPSTGGRQGSRHEQARDSS 3746
Q++T+ + S S + ++SAH GP+ + E A +SS
Sbjct: 1095 VQQATKAPESSDDSEDSSDSSSGSEEDGEGPQGAKSAHTLVGPTPSRTETLVEETAAESS 1154
Query: 3747 RHSASQEGQDTIRGH--PGSRRGGRQGSYHEQSVDRS-GHSGSHHSHTTSQGRSDASHGQ 3803
Q + G+ PG Q S +D S S + + G+ +A Q
Sbjct: 1155 EDDVVAPSQSLLSGYMTPGLTPANSQASKATPKLDSSPSVSSTLAAKDDPDGKQEAKPQQ 1214
Query: 3804 SGSRSASRETRNEEQSGDGSRHS-----GSRHHEASTQADSSRHSQSGQGESAGSRRSRR 3858
+ + + E SG + S G+ + +AST A S +Q G+ ++
Sbjct: 1215 AAGMLSPKTGGKEAASGTTPQKSRKPKKGAGNPQASTLALQSNITQCLLGQPWPLNEAQV 1274
Query: 3859 QGSSV---------SQDSDSEAYPEDSERRSESASRNHHGSSREQSRDGSRHPGSSHRDT 3909
Q S V + + E S + ES R G S+
Sbjct: 1275 QASVVKVLTELLEQERKKVVDTTKESSRKGWESRKRKLSGDQPAARTPRSKKKKKLGAGE 1334
Query: 3910 ASHVQSSPVQSDSSTAKEHGHFSSLSQDSAYHSGIQSRGS 3949
SP + S+T+K S D G S GS
Sbjct: 1335 GGEASVSP-EKTSTTSKGKAKRDKASGDVKEKKGKGSLGS 1373
Score = 47.0 bits (110), Expect = 4e-04
Identities = 81/409 (19%), Positives = 138/409 (33%), Gaps = 35/409 (8%)
Query: 3543 SDSQGHSEDSERWSGSASRNHRGSAQEQSRDGSRHPTSHHEDRAGHGHSAESSRQSGTHH 3602
S S+ E+ E + +A R ++ S G+ P+S E A + S H
Sbjct: 83 STSESSEEEEEAEAETAKATPRLASTNSSVLGADLPSSMKEKAKAETEKAGKTGNSMPHP 142
Query: 3603 AENSSGGQAASSHEQARSSAGERHGSHHQQSADSSRHSGIGHGQASSAVRDSGHRGSSGS 3662
A + S +S+ + + ++ + G V S+G
Sbjct: 143 ATGKTVANLLSGKSPRKSAEPSANTTLVSETEEEGSVPAFGAAAKPGMV-------SAGQ 195
Query: 3663 QASDSEGHSEDSDTQSVSAHGQAGPHQQ-----SHQESTRGRSAGRSGRSGSFLYQVS-- 3715
S SE S SD V P Q S +ES ++A G+ G QV
Sbjct: 196 ADSSSEDTSSSSDETDVEGKPSVKPAQVKASSVSTKESPARKAAPAPGKVGDVTPQVKGG 255
Query: 3716 ----------THEQSESAHGRAGPSTGGRQGSRHEQARDSSRHSASQEGQDTIRGHPGSR 3765
E+SES+ + G+R Q + S + + +G PG
Sbjct: 256 ALPPAKRAKKPEEESESSEEGSESEEEAPAGTR-SQVKASEKILQVRAASAPAKGTPGKG 314
Query: 3766 RG----GRQGSYHEQSVDRSGHSGSHHSHTTSQGRSDASHGQSGSRSA--SRETRNEEQS 3819
G+ G+ Q+ S ++S+ SD+ +++ ++ + Q
Sbjct: 315 ATPAPPGKAGAVASQT---KAGKPEEDSESSSEESSDSEEETPAAKALLQAKASGKTSQV 371
Query: 3820 GDGSRHSGSRHHEASTQADSSRHSQSGQGESAGSRRSRRQGSSVSQDSDSEAYPEDSERR 3879
G S + + + A + + AG R Q SS DS+ EA +
Sbjct: 372 GAASAPAKESPRKGAAPAPPGKTGPAVAKAQAGKREEDSQSSSEESDSEEEAPAQAKPSG 431
Query: 3880 SESASRNHHGSSREQSRDGSR-HPGSSHRDTASHVQSSPVQSDSSTAKE 3927
R ++E R G+ P A+ VQ + DS ++ E
Sbjct: 432 KAPQVRAASAPAKESPRKGAAPAPPRKTGPAAAQVQVGKQEEDSRSSSE 480
Score = 40.4 bits (93), Expect = 0.036
Identities = 117/580 (20%), Positives = 190/580 (32%), Gaps = 105/580 (18%)
Query: 3219 SDSEGHSEDSERWSGSASRNHRGSVQEQSRHGSRHPRSHHEDRAGHGHSADRSRQS---- 3274
S SE E+ E + +A R + S G+ P S E A ++ S
Sbjct: 83 STSESSEEEEEAEAETAKATPRLASTNSSVLGADLPSSMKEKAKAETEKAGKTGNSMPHP 142
Query: 3275 --GTRHAETSSGGQAASSHEQARS----SPGERHGSRHQQSADSSRHSGIPRGQASSAVR 3328
G A SG S E + + S E GS A +++ + GQA S+
Sbjct: 143 ATGKTVANLLSGKSPRKSAEPSANTTLVSETEEEGSVPAFGA-AAKPGMVSAGQADSSSE 201
Query: 3329 DSRHWGSSGSQASDSEGHSEESDTQSVSGHGQAGPHQQSHQESARDRSGGRSGRSGSFLY 3388
D+ SS S +D EG Q + S +ES ++ G+ G
Sbjct: 202 DT----SSSSDETDVEGKPSVKPAQVKAS-------SVSTKESPARKAAPAPGKVGDVTP 250
Query: 3389 QVSTHEQSESAHGRTRTSTGRRQGSHHEQARDSSRHSASQEGQDTIRGHPGSSRRGRQGS 3448
QV G R + E +S+EG ++ P +R + S
Sbjct: 251 QVK---------GGALPPAKRAKKPEEES-------ESSEEGSESEEEAPAGTRSQVKAS 294
Query: 3449 HYEQSVDRSGHSGSHHSHTTSQGRSDASRGQSGSRSASRQTRNDEQSGDGSRHSWSHHHE 3508
+ + + + + T +G + A G++G+ ++ + E+ + S S E
Sbjct: 295 ---EKILQVRAASAPAKGTPGKGATPAPPGKAGAVASQTKAGKPEEDSESSSEESSDSEE 351
Query: 3509 ASTQAD-------SSRHSQSGQGQS-----------------AGPRTSRNQGSSVSQDSD 3544
+ A S + SQ G + GP ++ Q +DS
Sbjct: 352 ETPAAKALLQAKASGKTSQVGAASAPAKESPRKGAAPAPPGKTGPAVAKAQAGKREEDSQ 411
Query: 3545 SQGHSEDSERWSGSASRNHRGSAQEQSRDGSRHPTSHHEDRAGHGHSAESSRQSGTHHAE 3604
S DSE A G A + R ++ ++ G + R++G A+
Sbjct: 412 SSSEESDSEE-EAPAQAKPSGKAPQ-----VRAASAPAKESPRKGAAPAPPRKTGPAAAQ 465
Query: 3605 NSSGGQAASSHEQARSSAGERH-------------GSHHQQSADSSRHSG-IGHGQA--- 3647
G Q S + S +R G Q S+ G +G G
Sbjct: 466 VQVGKQEEDSRSSSEESDSDREALAAMNAAQVKPLGKSPQVKPASTMGMGPLGKGAGPVP 525
Query: 3648 SSAVRDSGHRGSSGSQASDSEGHSED-SDTQSVSAHGQAGPHQQS------HQESTRGRS 3700
V + G DSE SE+ SD+ P Q+ + T +
Sbjct: 526 PGKVGPATPSAQVGKWEEDSESSSEESSDSSDGEVPTAVAPAQEKSLGNILQAKPTSSPA 585
Query: 3701 AGRSGRSGSFLYQV----------STHEQSESAHGRAGPS 3730
G ++G QV S+ E S+SA P+
Sbjct: 586 KGPPQKAGPVAVQVKAEKPMDNSESSEESSDSADSEEAPA 625
>gi|21361282 splicing factor, arginine/serine-rich 4 [Homo sapiens]
Length = 494
Score = 82.4 bits (202), Expect = 8e-15
Identities = 108/468 (23%), Positives = 179/468 (38%), Gaps = 58/468 (12%)
Query: 3461 GSHHSHTTSQGRSDASRGQSGSRSASRQTRNDEQ---SGDGSRHSWSHHHEASTQADSSR 3517
G + GRS +SG TR + + SR SW + QA
Sbjct: 72 GPRRDGSYGSGRSGYGYRRSGRDKYGPPTRTEYRLIVENLSSRCSWQDLKDYMRQAGEVT 131
Query: 3518 HSQSGQGQSAGPRTSRNQGSSVSQDSDSQGHSEDSERWSGSASRNHRGSAQEQSRDGSRH 3577
++ + +G+ +N+G V + E+ G+ N R + + GSR
Sbjct: 132 YADAHKGR-------KNEG--VIEFVSYSDMKRALEKLDGTEV-NGRKIRLVEDKPGSRR 181
Query: 3578 PTSHHEDRAGHGHSAESSRQSGTHHAENSSGGQAAS-SHEQARSSAGERHGSHHQQSADS 3636
S+ R+ HS SR + + + SG +S S ++RS +G R S + + S
Sbjct: 182 RRSYSRSRS---HSRSRSRSRHSRKSRSRSGSSKSSHSKSRSRSRSGSRSRSKSRSRSQS 238
Query: 3637 SRHSGIGHGQASSAVRDSGHRGSSGSQASDSEGHSEDS--DTQSVSAHGQAGPHQQSHQE 3694
S ++ S + S+G S S+ +E+ + +V P + +
Sbjct: 239 RSRSKKEKSRSPSKEKSRSRSHSAGKSRSKSKDQAEEKIQNNDNVGKPKSRSPSRHKSKS 298
Query: 3695 STRGRSAGRSGRSGSFLYQVSTHEQSESAHGRAGPSTGGRQGSRHEQARDS-SRHSASQE 3753
+R RS R +V ++ + GR+ + + SR S SR + +
Sbjct: 299 KSRSRSQER---------RVEEEKRGSVSRGRSQEKSLRQSRSRSRSKGGSRSRSRSRSK 349
Query: 3754 GQDTIRGHPGSRRGGRQGSYHEQSVDRSGHSGSHHSHTTSQGR------SDASHGQSGSR 3807
+D +G SR R S +RS GS + +D S +S SR
Sbjct: 350 SKDKRKGRKRSREESRSRSRSRSKSERSRKRGSKRDSKAGSSKKKKKEDTDRSQSRSPSR 409
Query: 3808 SASRETRNEEQSGDGSRHSGSRHHEASTQADSSRHSQSGQGESAGSRRSRRQGSSVSQDS 3867
S S+E R H +++SS+ G+ E+AG+ + R S S
Sbjct: 410 SVSKE----------------REH---AKSESSQREGRGESENAGTNQETRSRSR-SNSK 449
Query: 3868 DSEAYPEDSERRSESASRNHHGSSREQSRDGSRHPGSSHRDTASHVQS 3915
P +S RS+SAS+ S+ +SR SR P S + SH +S
Sbjct: 450 SKPNLPSESRSRSKSASKT-RSRSKSRSRSASRSPSRSR--SRSHSRS 494
Score = 80.9 bits (198), Expect = 2e-14
Identities = 85/300 (28%), Positives = 124/300 (41%), Gaps = 35/300 (11%)
Query: 1166 RAHPGSRRGGRQGSHHEQSVDRSGHSGSHHSHTTSQGRSDA-SHGQSGSRSASR-QTRKD 1223
R+H SR R H +S RSG S S HS + S+ RS + S +S SRS SR +++K+
Sbjct: 189 RSHSRSRSRSR---HSRKSRSRSGSSKSSHSKSRSRSRSGSRSRSKSRSRSQSRSRSKKE 245
Query: 1224 KQSGDGSRHSGSRHHEAASWADSSR---------HSQVGQEQSSGSRTSRHQGSSVSQDS 1274
K S SR H A S+ + VG+ +S SRH+ S S+
Sbjct: 246 KSRSPSKEKSRSRSHSAGKSRSKSKDQAEEKIQNNDNVGKPKSRSP--SRHKSKSKSRSR 303
Query: 1275 DSERHSDDSERLSGSASRNHHGSSREQSRDGSRHPGFHQEDRASHGHSADSSRQSGTHHT 1334
ER ++ +R S S R+ S R QSR SR G + S S D +
Sbjct: 304 SQERRVEEEKRGSVSRGRSQEKSLR-QSRSRSRSKGGSRSRSRSRSKSKDKRKGRKRSRE 362
Query: 1335 ESSSHGQAVSSHEQARSSPGERHG----SRHQQSADSSRHSGIG----------HRQASS 1380
ES S ++ S E++R +R S+ ++ D+ R H ++ S
Sbjct: 363 ESRSRSRSRSKSERSRKRGSKRDSKAGSSKKKKKEDTDRSQSRSPSRSVSKEREHAKSES 422
Query: 1381 AVRDSGHRGSSGSQVTNSEGHSEDSDTQSVSAHGQAGPHQQSHKESARGQSGESSGRSRS 1440
+ R+ RG S + TN E S + +S +SA S RSRS
Sbjct: 423 SQREG--RGESENAGTNQETRSRSRSNS--KSKPNLPSESRSRSKSASKTRSRSKSRSRS 478
Score = 79.7 bits (195), Expect = 5e-14
Identities = 77/336 (22%), Positives = 125/336 (37%), Gaps = 25/336 (7%)
Query: 3246 QSRHGSRHPRSHHEDRAGHGHSADRSRQSGTRHAETSSGGQAAS-SHEQARSSPGERHGS 3304
+ + GSR RS+ R+ HS RSR +R + + SG +S S ++RS G R S
Sbjct: 174 EDKPGSRRRRSYSRSRS---HSRSRSRSRHSRKSRSRSGSSKSSHSKSRSRSRSGSRSRS 230
Query: 3305 RHQQSADSSRHSGIPRGQASSAVRDSRHWGSSGSQASDSEGHSEES--DTQSVSGHGQAG 3362
+ + + S S + ++ S + S+G S S+ +EE + +V
Sbjct: 231 KSRSRSQSRSRSKKEKSRSPSKEKSRSRSHSAGKSRSKSKDQAEEKIQNNDNVGKPKSRS 290
Query: 3363 PHQQSHQESARDRSGGRSGRSGSFLYQVSTHEQSESAHGRTRTSTGRRQGSHHEQARDSS 3422
P + + +R RS E+ R S GR Q Q+R S
Sbjct: 291 PSRHKSKSKSRSRS----------------QERRVEEEKRGSVSRGRSQEKSLRQSRSRS 334
Query: 3423 RHSASQEGQDTIRGHPGSSRRGRQGSHYEQSVDRSGHSGSHHSHTTSQGRSDASRGQSGS 3482
R + R R+GR+ S E S S S R D+ G S
Sbjct: 335 RSKGGSRSRSRSRSKSKDKRKGRKRSREESRSRSRSRSKSERSRKRGSKR-DSKAGSSKK 393
Query: 3483 RSASRQTRNDEQSGDGSRHSWSHH--HEASTQADSSRHSQSGQGQSAGPRTSRNQGSSVS 3540
+ R+ +S S H E+S + +G Q R+ N S +
Sbjct: 394 KKKEDTDRSQSRSPSRSVSKEREHAKSESSQREGRGESENAGTNQETRSRSRSNSKSKPN 453
Query: 3541 QDSDSQGHSEDSERWSGSASRNHRGSAQEQSRDGSR 3576
S+S+ S+ + + + R +++ SR SR
Sbjct: 454 LPSESRSRSKSASKTRSRSKSRSRSASRSPSRSRSR 489
Score = 79.0 bits (193), Expect = 9e-14
Identities = 81/333 (24%), Positives = 140/333 (42%), Gaps = 29/333 (8%)
Query: 1620 GSAREQSRHGSRNPRSHQEDRASHGHSAESSRQSGTRHAETSSGGQAASSQEQARSSPGE 1679
GS R +S SR SH R+ HS +S +SG+ +++ S+ ++RS G
Sbjct: 178 GSRRRRSYSRSR---SHSRSRSRSRHSRKSRSRSGS--------SKSSHSKSRSRSRSGS 226
Query: 1680 RHGSRHQQSADSSTDSGTGRRQDSSVVGDSGNRGSSGSQASDSEGHSEE--SDTQSVSAH 1737
R S+ + + S + S + + S S+G S S+ +EE + +V
Sbjct: 227 RSRSKSRSRSQSRSRSKKEKSRSPSKEKSRSRSHSAGKSRSKSKDQAEEKIQNNDNVGKP 286
Query: 1738 GQAGPHQQSHQESTRGQSGER---SGRSGSFLYQVSTHEQSESAHGRTGPSTGGRQRSR- 1793
P + + +R +S ER + GS S + + R+ G R RSR
Sbjct: 287 KSRSPSRHKSKSKSRSRSQERRVEEEKRGSVSRGRSQEKSLRQSRSRSRSKGGSRSRSRS 346
Query: 1794 HEQARD--SSRHSASQEGQDTIRGHPGSSRGGRQGSHYEQSVDSSGHSGSHHSHTTSQER 1851
+++D R + +E + R S R ++GS + S S +E
Sbjct: 347 RSKSKDKRKGRKRSREESRSRSRSRSKSERSRKRGSKRDSKAGS--------SKKKKKED 398
Query: 1852 SDVSRGQSGSRSVSRQTRNEKQSGDGSRHSGSRHHEASSRADSSRHSQVGQGQSSGPRTS 1911
+D S+ +S SRSVS++ + K G + +++ SR + + + P S
Sbjct: 399 TDRSQSRSPSRSVSKEREHAKSESSQREGRGESENAGTNQETRSRSRSNSKSKPNLPSES 458
Query: 1912 RNQGSSVSQD-SDSQGHSEDSERW-SGSASRNH 1942
R++ S S+ S S+ S + R S S SR+H
Sbjct: 459 RSRSKSASKTRSRSKSRSRSASRSPSRSRSRSH 491
Score = 78.2 bits (191), Expect = 2e-13
Identities = 86/352 (24%), Positives = 138/352 (39%), Gaps = 39/352 (11%)
Query: 574 EEQSGDGTRHSGSRHHEASSQADSSRHSQVGQGQSSGPRTSRNQGSSVSQDSDSQGHSED 633
E++ G R S SR S SRHS+ + +S GSS S S S+ S
Sbjct: 174 EDKPGSRRRRSYSRSRSHSRSRSRSRHSRKSRSRS---------GSSKSSHSKSRSRSRS 224
Query: 634 SERWSGSASRNHHGSAQEQSRDGSRHPRSHHEDRAGH--GHSADSSRKSGTRHTQNSSSG 691
R S S SR+ S ++ SR P H G S S+ QN+ +
Sbjct: 225 GSR-SRSKSRSRSQSRSRSKKEKSRSPSKEKSRSRSHSAGKSRSKSKDQAEEKIQNNDNV 283
Query: 692 QAASSHEQARSSAGERHGSRHQLQSADSSRHSGTGHGQASS-AVRDSGHRG-SSGSQATD 749
S +R + + SR Q + + + G++ ++R S R S G +
Sbjct: 284 GKPKSRSPSRHKSKSKSRSRSQERRVEEEKRGSVSRGRSQEKSLRQSRSRSRSKGGSRSR 343
Query: 750 SEGHSEDSDTQSVSGHGQAGHHQQSHQESARDRSGERSRRSGSFLYQVSTHKQSESSHGW 809
S S+ D + G+ ++S S ERSR+ GS + +S G
Sbjct: 344 SRSRSKSKDKRK----GRKRSREESRSRSRSRSKSERSRKRGS---------KRDSKAGS 390
Query: 810 TGPSTGVRQGSHHEQARDNSRHSASQDGQDTIRGHPGSSRRGRQGSHHEQSVDRSGHSGS 869
+ ++ + Q+R SR + + R H S R+G ++ + + S
Sbjct: 391 SKKKK--KEDTDRSQSRSPSRSVSKE------REHAKSESSQREGRGESENAGTNQETRS 442
Query: 870 HHSHTTSQGRSDASRGQSGSRSASRT-TRNEEQSRDGSR---HSGSRHHEAS 917
+ + S +S S+SAS+T +R++ +SR SR S SR H S
Sbjct: 443 RSRSNSKSKPNLPSESRSRSKSASKTRSRSKSRSRSASRSPSRSRSRSHSRS 494
Score = 77.4 bits (189), Expect = 3e-13
Identities = 88/322 (27%), Positives = 130/322 (40%), Gaps = 30/322 (9%)
Query: 2145 SRGGRQGSHQEQSVDRSGHSGSHHSHTTSQGRSDA-SRGQSGSRSASRKTYDKEQSGDGS 2203
SR + H +S RSG S S HS + S+ RS + SR +S SRS SR KE+S S
Sbjct: 192 SRSRSRSRHSRKSRSRSGSSKSSHSKSRSRSRSGSRSRSKSRSRSQSRSRSKKEKSRSPS 251
Query: 2204 RH-SGSHHHEASSWADSSR---------HSLVGQGQSSGPRTSRPRGSSVSQDSDSEGHS 2253
+ S S H A S+ + VG+ +S P SR + S S+ E
Sbjct: 252 KEKSRSRSHSAGKSRSKSKDQAEEKIQNNDNVGKPKSRSP--SRHKSKSKSRSRSQERRV 309
Query: 2254 EDSERRSGSASRNHHGSAQEQSRDGSRHPRSHHEDRAGHGHSAESSRQSGTHHAENSSGG 2313
E+ +R GS SR G +QE+S R RS + G SR +++ G
Sbjct: 310 EEEKR--GSVSR---GRSQEKS---LRQSRSRSRSKGG-----SRSRSRSRSKSKDKRKG 356
Query: 2314 QAASSHEQARSSAGERHGSHHQQSADSSRHSGIGHGQASSAVRDSGHRGSSGSQASDSEG 2373
+ S E++RS + R S + S R S G + ++ R S S +
Sbjct: 357 R-KRSREESRSRSRSRSKSERSRKRGSKRDSKAGSSKKKK--KEDTDRSQSRSPSRSVSK 413
Query: 2374 HSEDSDTQSVSAHGQAGPHQQSHQESTRGRSAGRSGRSGSFLYQVSTHEQSESAHGRTGT 2433
E + ++S G+ + TR RS S +S L S ++ R+ +
Sbjct: 414 EREHAKSESSQREGRGESENAGTNQETRSRSRSNS-KSKPNLPSESRSRSKSASKTRSRS 472
Query: 2434 STGGRQGSHHKQARDSSRHSTS 2455
+ R S S HS S
Sbjct: 473 KSRSRSASRSPSRSRSRSHSRS 494
Score = 77.0 bits (188), Expect = 3e-13
Identities = 84/370 (22%), Positives = 136/370 (36%), Gaps = 35/370 (9%)
Query: 423 SDSEGHSENSDTQSVSGHGKAGLRQQSHQESTRGRSGERSGRSGSSLYQVSTHEQPDSAH 482
SD + E D V+G +R + +R R RS S + S H
Sbjct: 151 SDMKRALEKLDGTEVNGRK---IRLVEDKPGSRRRRSYSRSRSHS-------RSRSRSRH 200
Query: 483 GRTGTSTGGRQGSHHEQARDSSRHSASQEGQDTIRGHPGSSRGGRQGSHHEQSVNRSGHS 542
R S G S H ++R SR + + R R S E+S + S
Sbjct: 201 SRKSRSRSGSSKSSHSKSRSRSRSGSRSRSKSRSRSQ------SRSRSKKEKSRSPSKEK 254
Query: 543 GSHHSHTTSQGRSDASHGQSGSRSASRQTRNEEQSGDGTRHSGSRHHEASSQADSSRHSQ 602
SH+ + RS + A + +N + G S SRH S S+ +
Sbjct: 255 SRSRSHSAGKSRSKSKD------QAEEKIQNNDNVGKPKSRSPSRHKSKSKSRSRSQERR 308
Query: 603 VGQGQSSGPRTSRNQGSSVSQDSDSQGHSEDSERWSGSASRNHHGSAQEQSRDGSRHPRS 662
V + + R+Q S+ Q S S+ S+ GS SR+ S + R G + R
Sbjct: 309 VEEEKRGSVSRGRSQEKSLRQ-SRSRSRSK-----GGSRSRSRSRSKSKDKRKGRKRSRE 362
Query: 663 HHEDRAGHGHSADSSRKSGTRHTQNSSSGQAASSHE----QARSSAGERHGSRHQLQSAD 718
R+ ++ SRK G++ + S + + Q+RS + R +S
Sbjct: 363 ESRSRSRSRSKSERSRKRGSKRDSKAGSSKKKKKEDTDRSQSRSPSRSVSKEREHAKSES 422
Query: 719 SSRHSGTGHGQASSAVRDSGHRGSSGSQATDSEGHSEDSDTQSVSGHGQAGHHQQSHQES 778
S R G G++ +A + R S S + +S ++S S + + +
Sbjct: 423 SQRE---GRGESENAGTNQETRSRSRSNSKSKPNLPSESRSRSKSASKTRSRSKSRSRSA 479
Query: 779 ARDRSGERSR 788
+R S RSR
Sbjct: 480 SRSPSRSRSR 489
Score = 76.6 bits (187), Expect = 5e-13
Identities = 85/348 (24%), Positives = 136/348 (39%), Gaps = 41/348 (11%)
Query: 1355 ERHGSRHQQSADSSRHSGIGHRQASSAVRDSGHRGSSGSQVTNSEGHSEDSDTQSVSAHG 1414
++ GSR ++S SR ++ + + GSS S + S S +
Sbjct: 175 DKPGSRRRRSYSRSRSHSRSRSRSRHSRKSRSRSGSSKSSHSKSRSRSRSGSRSRSKSRS 234
Query: 1415 QAGPHQQSHKESARGQSGE-------SSGRSRSFLYQVSSHEQSEST--HGQTAPSTGGR 1465
++ +S KE +R S E S+G+SRS S +Q+E + R
Sbjct: 235 RSQSRSRSKKEKSRSPSKEKSRSRSHSAGKSRS-----KSKDQAEEKIQNNDNVGKPKSR 289
Query: 1466 QGSRHEQARNSSRHSASQDGQDTIRGHPGSSRGGRQGSYHEQSVDRSGHSGYHHSHTTPQ 1525
SRH+ S S + ++ RG SRG Q QS RS G S + +
Sbjct: 290 SPSRHKSKSKSRSRSQERRVEEEKRG--SVSRGRSQEKSLRQSRSRSRSKGGSRSRSRSR 347
Query: 1526 GRSDASHGQSGPRSASRQTRNEEQSGDGSRHSGSRHHEPSTRAGSSRHSQVGQGESAGSK 1585
+S R +++R E +S SR R S + GS R S+ G SK
Sbjct: 348 SKS------KDKRKGRKRSREESRSRSRSRSKSER----SRKRGSKRDSKAGS-----SK 392
Query: 1586 TSRRQGSSVSQDRDSEGHSEDSERRSESASRNHYGS--AREQSRHGSRNPRSHQEDRASH 1643
+++ + SQ R S RS S R H S ++ + R S N ++QE R+
Sbjct: 393 KKKKEDTDRSQSR--------SPSRSVSKEREHAKSESSQREGRGESENAGTNQETRSRS 444
Query: 1644 GHSAESSRQSGTRHAETSSGGQAASSQEQARSSPGERHGSRHQQSADS 1691
+++S + S S+ ++RS R SR + + S
Sbjct: 445 RSNSKSKPNLPSESRSRSKSASKTRSRSKSRSRSASRSPSRSRSRSHS 492
Score = 75.5 bits (184), Expect = 1e-12
Identities = 86/388 (22%), Positives = 140/388 (36%), Gaps = 28/388 (7%)
Query: 1376 RQASSAVRDSGHRGSSGSQVTNSEGHSEDSDT-QSVSAHGQAGPHQQSHKESARGQSGES 1434
RQA H+G V +S+ + + G + ++ + S
Sbjct: 125 RQAGEVTYADAHKGRKNEGVIEFVSYSDMKRALEKLDGTEVNGRKIRLVEDKPGSRRRRS 184
Query: 1435 SGRSRSFLYQVSSHEQSESTHGQTAPSTGGRQGSRHEQARNSSRHSASQDGQDTIRGHPG 1494
RSRS S +S S H + + S G S H ++R+ SR + + R
Sbjct: 185 YSRSRSH-----SRSRSRSRHSRKSRSRSGSSKSSHSKSRSRSRSGSRSRSKSRSRSQ-- 237
Query: 1495 SSRGGRQGSYHEQSVDRSGHSGYHHSHTTPQGRSDASHGQSGPRSASRQTRNEEQSGDGS 1554
R S E+S S SH+ + RS + A + +N + G
Sbjct: 238 ----SRSRSKKEKSRSPSKEKSRSRSHSAGKSRSKSKD------QAEEKIQNNDNVGKPK 287
Query: 1555 RHSGSRHHEPSTRAGSSRHSQVGQGESAGSKTSRRQGSSVSQDRDSEGHSEDSERRSESA 1614
S SRH S S+ +V + + R Q S+ Q R S RS S
Sbjct: 288 SRSPSRHKSKSKSRSRSQERRVEEEKRGSVSRGRSQEKSLRQSRSRSRSKGGS--RSRSR 345
Query: 1615 SRNHYGSAREQSRHGSRNPRSHQEDRASHGHSAESSRQSGTRHAETSSGGQAASSQEQAR 1674
SR S + R G + R R+ +E SR+ G++ + + ++ R
Sbjct: 346 SR----SKSKDKRKGRKRSREESRSRSRSRSKSERSRKRGSKRDSKAGSSKKKKKEDTDR 401
Query: 1675 S---SPGERHGSRHQQSADSSTDSGTGRRQDSSVVGDSGNRGSSGSQASDSEGHSEESDT 1731
S SP R S+ ++ A S + GR + + + R S S + ES +
Sbjct: 402 SQSRSP-SRSVSKEREHAKSESSQREGRGESENAGTNQETRSRSRSNSKSKPNLPSESRS 460
Query: 1732 QSVSAHGQAGPHQQSHQESTRGQSGERS 1759
+S SA + + ++R S RS
Sbjct: 461 RSKSASKTRSRSKSRSRSASRSPSRSRS 488
Score = 75.5 bits (184), Expect = 1e-12
Identities = 86/398 (21%), Positives = 146/398 (36%), Gaps = 63/398 (15%)
Query: 67 KKIDFTEFLLMVFKLAQAYYESTRKENLPISGHKHRKHSHHDKHEDNKQEENKENRKRPS 126
+K+D TE +L + S R+ + S H + +H K + K
Sbjct: 158 EKLDGTEVNGRKIRLVEDKPGSRRRRSYSRS-RSHSRSRSRSRHS-RKSRSRSGSSKSSH 215
Query: 127 SLERRNNRKGNKGRSKSPRETGGKRHESSSEKKERKGYSPTHREEEYGKNHHNSSKKEKN 186
S R +R G++ RSKS R +S S K+ K SP+ KEK+
Sbjct: 216 SKSRSRSRSGSRSRSKSR-----SRSQSRSRSKKEKSRSPS---------------KEKS 255
Query: 187 KTENTRLGDNRKRLSERLEEKEDNEEGVYDYENTGRMTQKWIQSGHIATYYTIQDEAYDT 246
++ + G +R + ++ EEK N + V G + + ++
Sbjct: 256 RSRSHSAGKSRSKSKDQAEEKIQNNDNV----------------GKPKSRSPSRHKSKSK 299
Query: 247 TDSLLEENKIYERSRSSDGKSSSQVNRSRHENTSQVPLQESRTRKRRGSRVSQDRDSEGH 306
+ S +E ++ E R S + SQ R SR+R + GSR S
Sbjct: 300 SRSRSQERRVEEEKRGSVSRGRSQEKSLRQ--------SRSRSRSKGGSR----SRSRSR 347
Query: 307 SEDSERHSGSASRNHHGSAWEQSRDGSRHPRSHDEDRASHGHSADSSRQSGTRHAETSSR 366
S+ ++ G + +SR S R R S S+ ++ T +++ S
Sbjct: 348 SKSKDKRKGRKRSREESRSRSRSRSKSERSRKRGSKRDSKAGSSKKKKKEDTDRSQSRSP 407
Query: 367 GQTAS-SHEQARSSPGERHGSGHQQSADSSRHSATGRGQASSAVSDRGHRGSSGSQASDS 425
++ S E A+S +R G G ++A +++ + + R S S
Sbjct: 408 SRSVSKEREHAKSESSQREGRGESENAGTNQETRS-----------RSRSNSKSKPNLPS 456
Query: 426 EGHSENSDTQSVSGHGKAGLRQQSHQES-TRGRSGERS 462
E S + K+ R S S +R RS RS
Sbjct: 457 ESRSRSKSASKTRSRSKSRSRSASRSPSRSRSRSHSRS 494
Score = 75.1 bits (183), Expect = 1e-12
Identities = 79/338 (23%), Positives = 125/338 (36%), Gaps = 20/338 (5%)
Query: 328 QSRDGSRHPRSHDEDRASHGHSADSSRQSGTRHAETSSRGQTASSHEQARSSPGERHGSG 387
+ + GSR RS+ R SH S SR S + + S +++ S ++RS G R S
Sbjct: 174 EDKPGSRRRRSYSRSR-SHSRSRSRSRHSRKSRSRSGS-SKSSHSKSRSRSRSGSRSRSK 231
Query: 388 HQQSADSSRHSATGRGQASSAVSDRGHRGSSGSQASDSEGHSENSDTQSVSGHGKAGLRQ 447
+ + S S + ++ S R S+G S S+ +E Q+ GK R
Sbjct: 232 SRSRSQSRSRSKKEKSRSPSKEKSRSRSHSAGKSRSKSKDQAEEK-IQNNDNVGKPKSRS 290
Query: 448 QSHQESTRGRSGERSGRSGSSLYQVSTHEQPDSAHGRTGTSTGGRQGSHHEQARDSSRHS 507
S +S + +S RS E+ R S G Q Q+R SR
Sbjct: 291 PSRHKS-KSKSRSRS------------QERRVEEEKRGSVSRGRSQEKSLRQSRSRSRSK 337
Query: 508 ASQEGQDTIRGHPGSSRGGRQGSHHEQSVNRSGHSGSHHSHTTSQGRSDASHGQSGSRSA 567
+ R R GR+ S E S S S R D+ G S +
Sbjct: 338 GGSRSRSRSRSKSKDKRKGRKRSREESRSRSRSRSKSERSRKRGSKR-DSKAGSSKKKKK 396
Query: 568 SRQTRNEEQSGDGTRHSGSRH--HEASSQADSSRHSQVGQGQSSGPRTSRNQGSSVSQDS 625
R++ +S + H E+S + G Q + R+ N S + S
Sbjct: 397 EDTDRSQSRSPSRSVSKEREHAKSESSQREGRGESENAGTNQETRSRSRSNSKSKPNLPS 456
Query: 626 DSQGHSEDSERWSGSASRNHHGSAQEQSRDGSR-HPRS 662
+S+ S+ + + + +++ SR SR H RS
Sbjct: 457 ESRSRSKSASKTRSRSKSRSRSASRSPSRSRSRSHSRS 494
Score = 75.1 bits (183), Expect = 1e-12
Identities = 89/354 (25%), Positives = 142/354 (40%), Gaps = 36/354 (10%)
Query: 3604 ENSSGGQAASSHEQARSSAGERHGSHHQQSADS-SRHSGIGHGQASSAVRDSGHRGSSGS 3662
E+ G + S+ ++RS + R S H + + S S S H ++ S R S
Sbjct: 174 EDKPGSRRRRSYSRSRSHSRSRSRSRHSRKSRSRSGSSKSSHSKSRSRSRSGSRSRSKSR 233
Query: 3663 QASDSEGHSEDSDTQSVSAHGQAGPHQQSHQESTRGR--SAGRSGRSGSFLYQVSTHEQS 3720
S S S+ ++S S +E +R R SAG+S RS S + E+
Sbjct: 234 SRSQSRSRSKKEKSRSPS------------KEKSRSRSHSAGKS-RSKS---KDQAEEKI 277
Query: 3721 ESAHGRAGPSTGGRQGSRHEQARDSSRHSASQEGQDTIRGHPGSRRGGRQGSYHEQSVDR 3780
++ P + R SRH+ S S + ++ RG RG Q QS R
Sbjct: 278 QNNDNVGKPKS--RSPSRHKSKSKSRSRSQERRVEEEKRG--SVSRGRSQEKSLRQSRSR 333
Query: 3781 SGHSGSHHSHTTSQGRSDASHGQSGSRSASRETRNEEQSGDGSRHSGSRHHEASTQADSS 3840
S G S + S+ RS + + G + + E+R+ +S S S R + ++A SS
Sbjct: 334 SRSKGG--SRSRSRSRSKSKDKRKGRKRSREESRSRSRSRSKSERSRKRGSKRDSKAGSS 391
Query: 3841 RHSQSGQGESAGSRRSRRQGSSVSQDSDSEAYPEDSERRSESASRNHHGSSREQSRDGSR 3900
+ + + + SR R S + + SE+ + SE+A N SR +S S+
Sbjct: 392 KKKKKEDTDRSQSRSPSRSVSKEREHAKSESSQREGRGESENAGTNQETRSRSRSNSKSK 451
Query: 3901 HPGSSHRDTASHVQSSPVQSDSSTAKEHGHFSSLSQDSAYHSGIQSRGSPHSSS 3954
++ S S +K S S+ SA S +SR HS S
Sbjct: 452 ----------PNLPSESRSRSKSASKTRSRSKSRSR-SASRSPSRSRSRSHSRS 494
Score = 74.7 bits (182), Expect = 2e-12
Identities = 82/360 (22%), Positives = 137/360 (38%), Gaps = 22/360 (6%)
Query: 248 DSLLEENKIYERSRSSDGKSSSQVNRSRHENTSQVPLQESRTRKRRGSRVSQDRDSEGHS 307
+ ++E + R+ + ++VN + P R R S+ R HS
Sbjct: 142 EGVIEFVSYSDMKRALEKLDGTEVNGRKIRLVEDKPGSRRRRSYSRSRSHSRSRSRSRHS 201
Query: 308 EDSERHSGSASRNHHGSAWEQSRDGSR-----HPRSHDEDRASHGHSADSSRQSGTRHAE 362
S SGS S++ H + +SR GSR RS R+ S S++ +
Sbjct: 202 RKSRSRSGS-SKSSHSKSRSRSRSGSRSRSKSRSRSQSRSRSKKEKSRSPSKEKSRSRSH 260
Query: 363 TSSRGQTASSHEQARSSPGERHGSGHQQSADSSRHSATGRGQASSAVSDRGHRGSSGSQA 422
++ + + + S +QA G +S SRH + + ++ S + R +
Sbjct: 261 SAGKSR-SKSKDQAEEKIQNNDNVGKPKSRSPSRHKSKSKSRSRS----QERRVEEEKRG 315
Query: 423 SDSEGHS-ENSDTQSVS-GHGKAGLRQQSHQESTRGRSGERSGRSGSSLYQVSTHEQPDS 480
S S G S E S QS S K G R +S R RS + R G + S E
Sbjct: 316 SVSRGRSQEKSLRQSRSRSRSKGGSRSRS-----RSRSKSKDKRKGR---KRSREESRSR 367
Query: 481 AHGRTGTSTGGRQGSHHEQARDSSRHSASQEGQDTIRGHPGSSRGGRQGSHHEQSVNRSG 540
+ R+ + ++GS + SS+ ++ + P S + +S R G
Sbjct: 368 SRSRSKSERSRKRGSKRDSKAGSSKKKKKEDTDRSQSRSPSRSVSKEREHAKSESSQREG 427
Query: 541 HSGSHHSHTTSQGRSDASHGQSGSRSASRQTRNEEQSGDGTR-HSGSRHHEASSQADSSR 599
S ++ T + RS + + ++R+ +S TR S SR AS SR
Sbjct: 428 RGESENAGTNQETRSRSRSNSKSKPNLPSESRSRSKSASKTRSRSKSRSRSASRSPSRSR 487
Score = 74.7 bits (182), Expect = 2e-12
Identities = 87/338 (25%), Positives = 134/338 (39%), Gaps = 28/338 (8%)
Query: 3206 RRSRRQGSSVSQDSDSEGHSEDSERWSGSASRNHRGSVQEQSRHGSRHPRSHHEDRAGHG 3265
RRS + S S+ HS S SGS+ +H S + +SR GSR RS R
Sbjct: 182 RRSYSRSRSHSRSRSRSRHSRKSRSRSGSSKSSHSKS-RSRSRSGSR-SRSKSRSR---- 235
Query: 3266 HSADRSRQSGTRHAETSSGGQAASSHEQARSSPGERHGSRHQQSADSSRHSGIPRGQASS 3325
S RSR + S + SH +S R S+ Q + + + ++ S
Sbjct: 236 -SQSRSRSKKEKSRSPSKEKSRSRSHSAGKS----RSKSKDQAEEKIQNNDNVGKPKSRS 290
Query: 3326 AVRDSRHWGSSGSQASDSEGHSEESDTQSVS-GHGQAGPHQQSHQESARDRSGGRSGRSG 3384
SRH S S++ E EE SVS G Q +QS S R + G RS
Sbjct: 291 ---PSRHKSKSKSRSRSQERRVEEEKRGSVSRGRSQEKSLRQSRSRS-RSKGGSRSRSR- 345
Query: 3385 SFLYQVSTHEQSESAHGRTRTSTGRRQGSHHEQARDSSRHSASQEGQDTIRGHPGSSRRG 3444
S + + GR R+ R S + SR S+ +D+ G S ++
Sbjct: 346 ------SRSKSKDKRKGRKRSREESRSRSRSRSKSERSRKRGSK--RDSKAG--SSKKKK 395
Query: 3445 RQGSHYEQSVDRSGHSGSHHSHTTSQGRSDASRGQSGSRSASRQTRNDEQSGDGSRHSW- 3503
++ + QS S H S+ RG+S + +++TR+ +S S+ +
Sbjct: 396 KEDTDRSQSRSPSRSVSKEREHAKSESSQREGRGESENAGTNQETRSRSRSNSKSKPNLP 455
Query: 3504 SHHHEASTQADSSRHSQSGQGQSAGPRTSRNQGSSVSQ 3541
S S A +R + +SA SR++ S S+
Sbjct: 456 SESRSRSKSASKTRSRSKSRSRSASRSPSRSRSRSHSR 493
Score = 74.3 bits (181), Expect = 2e-12
Identities = 82/320 (25%), Positives = 133/320 (41%), Gaps = 27/320 (8%)
Query: 1710 GNRGSSGSQASDSEGHSEESDTQSVSAHGQAGPHQQSHQES-TRGQSGERSGRSGSFLYQ 1768
G+R S S S S + ++G + SH +S +R +SG RS Q
Sbjct: 178 GSRRRRSYSRSRSHSRSRSRSRHSRKSRSRSGSSKSSHSKSRSRSRSGSRSRSKSRSRSQ 237
Query: 1769 VSTHEQSESAHGRTGPSTGGRQRSRHEQARDSSRHSASQEGQDTIR-GHPGSSRGGRQGS 1827
+ + E + + + R S + +R S+ A ++ Q+ G P S R S
Sbjct: 238 SRSRSKKEKSRSPSKEKSRSRSHSAGK-SRSKSKDQAEEKIQNNDNVGKPKSRSPSRHKS 296
Query: 1828 HYEQSVDSSGHSGSHHSHTTSQERSDVSRGQSGSRSVSRQTRNEKQSGDGSRHSGSRHHE 1887
S S S ++R VSRG+S +S+ RQ+R+ +S GSR SR
Sbjct: 297 K------SKSRSRSQERRVEEEKRGSVSRGRSQEKSL-RQSRSRSRSKGGSR---SRSRS 346
Query: 1888 ASSRADSSRHSQVGQGQSSGPRTSRNQGSSVSQDSDSQGHSEDSERWSGSASRNHLGSAW 1947
S D + G+ +S SR++ S S+ S +G DS+ S S + +
Sbjct: 347 RSKSKDKRK----GRKRSREESRSRSRSRSKSERSRKRGSKRDSKAGS-SKKKKKEDTDR 401
Query: 1948 EQSRDGSR-------HPGSHHEDRAGHGHS--ADSSRQSGTRHTESSSRGQAASSHEQAR 1998
QSR SR H S R G G S A +++++ +R +S S ++R
Sbjct: 402 SQSRSPSRSVSKEREHAKSESSQREGRGESENAGTNQETRSRSRSNSKSKPNLPSESRSR 461
Query: 1999 SSAGERHGSHHQLQSADSSR 2018
S + + S + +S +SR
Sbjct: 462 SKSASKTRSRSKSRSRSASR 481
Score = 73.9 bits (180), Expect = 3e-12
Identities = 108/456 (23%), Positives = 172/456 (37%), Gaps = 58/456 (12%)
Query: 1358 GSRHQQSADSSRHSGIGHRQASSAVRDSGHRGSSGSQVTNSEGHSEDSDTQSVSAHGQAG 1417
G R S S R SG G+R++ R V N D +
Sbjct: 72 GPRRDGSYGSGR-SGYGYRRSGRDKYGPPTRTEYRLIVENLSSRCSWQDLKDYMRQAGEV 130
Query: 1418 PHQQSHKESARGQSGESSGRSRSFLYQVSSHEQSESTHGQTAPSTGGRQGSRHEQARNSS 1477
+ +HK R G S S + + +G+ + GSR ++ + S
Sbjct: 131 TYADAHK--GRKNEGVIEFVSYSDMKRALEKLDGTEVNGRKIRLVEDKPGSRRRRSYSRS 188
Query: 1478 RHSASQDGQDTIRGHPGSSRGGRQGSYHEQSVDRSGHSGYHHSHTTPQGRSDASHGQSGP 1537
R SR + + +S RSG S HS S +SG
Sbjct: 189 R---------------SHSRSRSRSRHSRKSRSRSGSSKSSHS-------KSRSRSRSGS 226
Query: 1538 RSASRQTRNEEQSGDGSRHSGSRHHEPSTRAGSSRHSQVGQGESAGSKTSRRQGSSVSQD 1597
RS S+ +R+ QS S+ SR PS SR G+ S S+ Q Q+
Sbjct: 227 RSRSK-SRSRSQSRSRSKKEKSR--SPSKEKSRSRSHSAGKSRS----KSKDQAEEKIQN 279
Query: 1598 RDSEGHSEDSERRSESASRNHYGSAREQSRHGSRNPRSHQEDRASHGHSAESS-RQSGTR 1656
D+ G + +S S SR H ++ +SR R + S G S E S RQS +R
Sbjct: 280 NDNVG-----KPKSRSPSR-HKSKSKSRSRSQERRVEEEKRGSVSRGRSQEKSLRQSRSR 333
Query: 1657 HAETSSGGQAASSQEQARSSPGE--RHGSRHQQSADSSTDSGTGRRQDSSVVGDSGNRGS 1714
S GG + S+ +++S R SR + + S + S + R + DS S
Sbjct: 334 --SRSKGGSRSRSRSRSKSKDKRKGRKRSREESRSRSRSRSKSERSRKRGSKRDSKAGSS 391
Query: 1715 SGSQASDSEGHSEESDTQSVSAHGQAGPHQQSHQESTRGQSGERSGRSGSFLYQVSTHEQ 1774
+ D++ S ++SVS +E + +S +R GR S T+++
Sbjct: 392 KKKKKEDTDRSQSRSPSRSVS----------KEREHAKSESSQREGRGES--ENAGTNQE 439
Query: 1775 SES---AHGRTGPSTGGRQRSRHEQARDSSRHSASQ 1807
+ S ++ ++ P+ RSR + A + S S+
Sbjct: 440 TRSRSRSNSKSKPNLPSESRSRSKSASKTRSRSKSR 475
Score = 73.9 bits (180), Expect = 3e-12
Identities = 84/321 (26%), Positives = 126/321 (39%), Gaps = 47/321 (14%)
Query: 1176 RQGSHHEQSV--------------------DRSGHSGSHHSHTTSQGRSDA-SHGQSGSR 1214
+ GS +S RSG S S HS + S+ RS + S +S SR
Sbjct: 176 KPGSRRRRSYSRSRSHSRSRSRSRHSRKSRSRSGSSKSSHSKSRSRSRSGSRSRSKSRSR 235
Query: 1215 SASR-QTRKDKQSGDGSRHSGSRHHEAASWADSSR---------HSQVGQEQSSGSRTSR 1264
S SR +++K+K S SR H A S+ + VG+ +S SR
Sbjct: 236 SQSRSRSKKEKSRSPSKEKSRSRSHSAGKSRSKSKDQAEEKIQNNDNVGKPKSRS--PSR 293
Query: 1265 HQGSSVSQDSDSERHSDDSERLSGSASRNHHGSSREQSRDGSRHPGFHQEDRASHGHSAD 1324
H+ S S+ ER ++ +R S S R+ S R QSR SR G + S S D
Sbjct: 294 HKSKSKSRSRSQERRVEEEKRGSVSRGRSQEKSLR-QSRSRSRSKGGSRSRSRSRSKSKD 352
Query: 1325 SSRQSGTHHTESSSHGQAVSSHEQARSSPGERH----GSRHQQSADSSRHSGIGHRQASS 1380
+ ES S ++ S E++R +R S+ ++ D+ R R S
Sbjct: 353 KRKGRKRSREESRSRSRSRSKSERSRKRGSKRDSKAGSSKKKKKEDTDRSQS---RSPSR 409
Query: 1381 AVRDSGHRGSSGSQVTNSEGHSEDSDTQSVSAHGQAGPHQQSHKESARGQSGESSGRSRS 1440
+V S S G SE++ T + +S+ +S ES RS+S
Sbjct: 410 SVSKEREHAKSESSQREGRGESENAGTNQ-----ETRSRSRSNSKSKPNLPSESRSRSKS 464
Query: 1441 FLYQVSSHEQSESTHGQTAPS 1461
+ S +S S +PS
Sbjct: 465 -ASKTRSRSKSRSRSASRSPS 484
Score = 73.9 bits (180), Expect = 3e-12
Identities = 90/343 (26%), Positives = 141/343 (41%), Gaps = 36/343 (10%)
Query: 1383 RDSGHRGSSGSQVTNSEGHSEDSDTQSVSAHGQAGPHQQSHKESARGQSGESSGRSRSFL 1442
R S R S S+ + HS S ++S S+ H +S S G S RSRS
Sbjct: 182 RRSYSRSRSHSRSRSRSRHSRKSRSRSGSSKSS---HSKSRSRSRSGSRSRSKSRSRSQS 238
Query: 1443 YQVSSHEQSESTHGQTAPSTGGRQGSRHEQARNSSRHSASQDGQDTIRGHPGSSRGGRQG 1502
S E+S S + + S G ++R+ S+ A + Q+ SR +
Sbjct: 239 RSRSKKEKSRSPSKEKSRSRSHSAG----KSRSKSKDQAEEKIQNNDNVGKPKSRSPSRH 294
Query: 1503 SYHEQSVDRSGHSGYHHSHTTPQGRSDASHGQSGPRSASRQTRNEEQSGDGSR-HSGSRH 1561
+S RS + R S G+S +S RQ+R+ +S GSR S SR
Sbjct: 295 KSKSKSRSRS-----QERRVEEEKRGSVSRGRSQEKSL-RQSRSRSRSKGGSRSRSRSRS 348
Query: 1562 HEPSTRAGSSRHSQVGQGESAG---SKTSRRQGSSVSQDRDSEGHSEDSERRSESASRNH 1618
R G R + + S S+ SR++GS RDS+ S +++ +
Sbjct: 349 KSKDKRKGRKRSREESRSRSRSRSKSERSRKRGSK----RDSKAGSSKKKKKED------ 398
Query: 1619 YGSAREQSRHGSRNPRSHQEDRASHGHSAESSRQSGTRHAETSSGGQ--AASSQEQARSS 1676
+ R QSR SR+ +E S ESS++ G +E + Q + S+ ++S
Sbjct: 399 --TDRSQSRSPSRSVSKEREHAKS-----ESSQREGRGESENAGTNQETRSRSRSNSKSK 451
Query: 1677 PGERHGSRHQQSADSSTDSGTGRRQDSSVVGDSGNRGSSGSQA 1719
P SR + + S T S + R S+ S +R S S++
Sbjct: 452 PNLPSESRSRSKSASKTRSRSKSRSRSASRSPSRSRSRSHSRS 494
Score = 72.8 bits (177), Expect = 7e-12
Identities = 80/338 (23%), Positives = 124/338 (36%), Gaps = 29/338 (8%)
Query: 977 QSRHGSRHPRSHHEDRAGHGHSADSSRQSGTPHAETSSGGQAASSHEQARSSP--GERHG 1034
+ + GSR RS+ R+ H S SR S S G + SSH ++RS G R
Sbjct: 174 EDKPGSRRRRSYSRSRS-HSRSRSRSRHS---RKSRSRSGSSKSSHSKSRSRSRSGSRSR 229
Query: 1035 SRHQQSADSSRHSGIPRRQASSAVRDSGHWGSSGSQASDSEGHSEESDTQSVSGHGQDGP 1094
S+ + + S S + ++ S + S+G S S+ +EE Q+ G+
Sbjct: 230 SKSRSRSQSRSRSKKEKSRSPSKEKSRSRSHSAGKSRSKSKDQAEEK-IQNNDNVGKPKS 288
Query: 1095 HQQSHQESARDWSGGRSGRSGSFIYQVSTHEQSESAHGRTRTSTGRRQGSHHEQARDSSR 1154
S +S S RS + E+ R S GR Q Q+R SR
Sbjct: 289 RSPSRHKSK---SKSRS----------RSQERRVEEEKRGSVSRGRSQEKSLRQSRSRSR 335
Query: 1155 HSASQEGQDTIRAHPGSRRGGRQGSHHEQSVDRSGHSGSHHSHTTSQGRSDASHGQSGSR 1214
+ R+ +R GR+ S E S S S+ R ++GS
Sbjct: 336 SKGGSRSRSRSRSKSKDKRKGRKRSREES----RSRSRSRSKSERSRKRGSKRDSKAGSS 391
Query: 1215 SASRQTRKDKQSGDGSRHSGSRHHEAASWADSSRHSQ-----VGQEQSSGSRTSRHQGSS 1269
++ D+ S S+ E A S R + G Q + SR+ + S
Sbjct: 392 KKKKKEDTDRSQSRSPSRSVSKEREHAKSESSQREGRGESENAGTNQETRSRSRSNSKSK 451
Query: 1270 VSQDSDSERHSDDSERLSGSASRNHHGSSREQSRDGSR 1307
+ S+S S + + + +SR SR SR
Sbjct: 452 PNLPSESRSRSKSASKTRSRSKSRSRSASRSPSRSRSR 489
Score = 72.8 bits (177), Expect = 7e-12
Identities = 85/346 (24%), Positives = 132/346 (38%), Gaps = 33/346 (9%)
Query: 1031 ERHGSRHQQSADSSRHSGIPRRQASSAVRDSGHWGSSGSQASDSEGHSEESDTQSVSGHG 1090
++ GSR ++S SR R ++ + + GSS S S S S
Sbjct: 175 DKPGSRRRRSYSRSRSHSRSRSRSRHSRKSRSRSGSSKSSHSKSRSRSRSGSRSRSKSRS 234
Query: 1091 QDGPHQQSHQESARDWSGGRSGRSGSFIYQVSTHEQSESAHGRTRTSTGRRQGSHHEQAR 1150
+ +S +E +R S +S RS S S + + A + + + + +R
Sbjct: 235 RSQSRSRSKKEKSRSPSKEKS-RSRSHSAGKSRSKSKDQAEEKIQNNDNVGKPKSRSPSR 293
Query: 1151 DSSR---HSASQEGQDTIRAHPGSRRGGRQGSHHEQSVDRSGHSGSHHSHTTSQGRS-DA 1206
S+ S SQE + RG Q QS RS G S + S+ +S D
Sbjct: 294 HKSKSKSRSRSQERRVEEEKRGSVSRGRSQEKSLRQSRSRSRSKGGSRSRSRSRSKSKDK 353
Query: 1207 SHGQSGSRSASRQTRKDKQSGDGSRHSGSRHHEAASWADSSRHSQVGQEQSSGSR-TSRH 1265
G+ SR SR + + + SR GS+ R S+ G + T R
Sbjct: 354 RKGRKRSREESRSRSRSRSKSERSRKRGSK-----------RDSKAGSSKKKKKEDTDRS 402
Query: 1266 QGSSVSQDSDSERHSDDSERLSGSASRNHHGSSREQSRDGSRHPGFHQEDRASHGHSADS 1325
Q S S+ ER SE SS+ + R S + G +QE R+ S +
Sbjct: 403 QSRSPSRSVSKEREHAKSE------------SSQREGRGESENAGTNQETRS---RSRSN 447
Query: 1326 SRQSGTHHTESSSHGQAVSSHEQARSSPGERHGSRHQQSADSSRHS 1371
S+ +ES S ++ +S ++RS R SR + S HS
Sbjct: 448 SKSKPNLPSESRSRSKS-ASKTRSRSKSRSRSASRSPSRSRSRSHS 492
Score = 72.0 bits (175), Expect = 1e-11
Identities = 80/303 (26%), Positives = 127/303 (41%), Gaps = 33/303 (10%)
Query: 3681 AHGQAGPHQQSHQESTRGRSAGRSGRSGSFLYQVSTHEQSES---AHGRAGPSTGGRQGS 3737
++ ++ H +S S R + RSGS S+H +S S + R+ + R S
Sbjct: 184 SYSRSRSHSRSRSRSRHSRKS--RSRSGS---SKSSHSKSRSRSRSGSRSRSKSRSRSQS 238
Query: 3738 RHEQARDSSRHSASQEGQDTIRGHPGSRRGGRQGSYHEQSVDRSGHSGSHHSHTTSQGRS 3797
R ++ SR + ++ + R H + + E+ + + + G S + S+ +S
Sbjct: 239 RSRSKKEKSRSPSKEKSRS--RSHSAGKSRSKSKDQAEEKIQNNDNVGKPKSRSPSRHKS 296
Query: 3798 DASHGQSGSRSASRETRNEEQSGDGSRHSGSRHHEASTQADSSRHSQSGQGESAGSRRSR 3857
+S SRS S+E R EE+ R S SR +Q S R S+S + S G RSR
Sbjct: 297 -----KSKSRSRSQERRVEEEK----RGSVSR---GRSQEKSLRQSRS-RSRSKGGSRSR 343
Query: 3858 RQGSSVSQDSDSEAYPEDSERRSESASRNHHGSSREQSRDGSRHPGSSHRDTASHVQSSP 3917
+ S S+D E RS S SR+ SR++ GSS + S
Sbjct: 344 SRSRSKSKDKRKGRKRSREESRSRSRSRSKSERSRKRGSKRDSKAGSSKKKKKEDTDRSQ 403
Query: 3918 VQSDS-STAKEHGHFSS---------LSQDSAYHSGIQSRGSPHSSSSYHYQSEGTERQK 3967
+S S S +KE H S S+++ + +SR +S S + SE R K
Sbjct: 404 SRSPSRSVSKEREHAKSESSQREGRGESENAGTNQETRSRSRSNSKSKPNLPSESRSRSK 463
Query: 3968 GQS 3970
S
Sbjct: 464 SAS 466
Score = 71.2 bits (173), Expect = 2e-11
Identities = 80/322 (24%), Positives = 132/322 (40%), Gaps = 29/322 (9%)
Query: 3435 RGHPGSSRRGRQGSHYEQSVDRSGHSGSHHSHTTSQGRSDA-SRGQSGSRSASRQTRNDE 3493
R H S R R H +S RSG S S HS + S+ RS + SR +S SRS SR E
Sbjct: 189 RSHSRSRSRSR---HSRKSRSRSGSSKSSHSKSRSRSRSGSRSRSKSRSRSQSRSRSKKE 245
Query: 3494 QSGDGSRHSWSHHHEASTQADSSRHSQSGQGQSAGPRTSRNQGSSVSQDSDSQGHSEDSE 3553
+S S+ + SR +G+ +S S++Q Q++D+ G +
Sbjct: 246 KSRSPSK-----------EKSRSRSHSAGKSRSK----SKDQAEEKIQNNDNVGKPK--- 287
Query: 3554 RWSGSASRNHRGSAQEQSRDGSRHPTSHHEDRAGHGHSAESSRQSGTHHAENSSGGQAAS 3613
S S SR H+ ++ +SR R G S E S + + + G ++ S
Sbjct: 288 --SRSPSR-HKSKSKSRSRSQERRVEEEKRGSVSRGRSQEKSLRQSRSRSRSKGGSRSRS 344
Query: 3614 -SHEQARSSAGERHGSHHQQSADSSRHSGIGHGQASSAVRDSGHRGSSGSQASDSEGHSE 3672
S +++ R S + + S S + + RDS S + D++
Sbjct: 345 RSRSKSKDKRKGRKRSREESRSRSRSRSKSERSRKRGSKRDSKAGSSKKKKKEDTDRSQS 404
Query: 3673 DSDTQSVSAHGQAGPHQQSHQESTRGRS--AGRSGRSGSFLYQVSTHEQSESAHGRAGPS 3730
S ++SVS + + S +E RG S AG + + S S + + + R+
Sbjct: 405 RSPSRSVSKEREHAKSESSQRE-GRGESENAGTNQETRSRSRSNSKSKPNLPSESRSRSK 463
Query: 3731 TGGRQGSRHEQARDSSRHSASQ 3752
+ + SR + S+ S S+
Sbjct: 464 SASKTRSRSKSRSRSASRSPSR 485
Score = 70.5 bits (171), Expect = 3e-11
Identities = 119/480 (24%), Positives = 184/480 (38%), Gaps = 76/480 (15%)
Query: 1161 GQDTIRAHP-GSRRGGRQGSHHEQSVDRSGHSGSHHSHTTSQGRSDASHGQSGSRSASRQ 1219
G+ I H G RR G GS R + T ++ R ++ S S Q
Sbjct: 62 GERVIVEHARGPRRDGSYGSGRSGYGYRRSGRDKYGPPTRTEYRLIV---ENLSSRCSWQ 118
Query: 1220 TRKD--KQSGD---GSRHSGSRHH---EAASWADSSRHSQ--------------VGQEQS 1257
KD +Q+G+ H G ++ E S++D R + V +
Sbjct: 119 DLKDYMRQAGEVTYADAHKGRKNEGVIEFVSYSDMKRALEKLDGTEVNGRKIRLVEDKPG 178
Query: 1258 SGSRTSRHQGSSVSQDSDSERHSDDSERLSGSASRNHHGSSREQSRDGSRHPGFHQEDRA 1317
S R S + S S+ RHS S SGS S++ H SR +SR GSR
Sbjct: 179 SRRRRSYSRSRSHSRSRSRSRHSRKSRSRSGS-SKSSHSKSRSRSRSGSR---------- 227
Query: 1318 SHGHSADSSRQSGTHHTESSSHGQAVSSHEQARSSPGERHGSRHQQSADSSRHSGIGHRQ 1377
S S S+ E S S ++ S+ R S+ Q + +G +
Sbjct: 228 SRSKSRSRSQSRSRSKKEKSRSPSKEKSRSRSHSAGKSRSKSKDQAEEKIQNNDNVGKPK 287
Query: 1378 ASSAVRDSGHRGSSGSQVTNSEGHSEDSDTQSVSAHGQAGPHQQSHKESARGQSGESSGR 1437
+ S R H+ S S+ + E E+ SVS G Q+ +R +S S G
Sbjct: 288 SRSPSR---HKSKSKSRSRSQERRVEEEKRGSVSR----GRSQEKSLRQSRSRS-RSKGG 339
Query: 1438 SRSFLYQVSSHEQSESTHGQTAPSTGGRQGSRHEQARNSSRHSASQDGQDTIRGHPGSSR 1497
SRS S +S+S + GR+ SR E++R+ SR S S+ + RG S+
Sbjct: 340 SRS-----RSRSRSKSKDKRK-----GRKRSR-EESRSRSR-SRSKSERSRKRGSKRDSK 387
Query: 1498 GGRQGSYHEQSVDRSGHSGYHHSHTTPQGRSDASHGQSGPRSASRQTRNEEQSGDGSRHS 1557
G ++ DRS S + + H +S S+ R+ R E ++ ++ +
Sbjct: 388 AGSSKKKKKEDTDRSQSRSPSRSVS-----KEREHAKS--ESSQREGRGESENAGTNQET 440
Query: 1558 GSRHHEPSTRAGSSRHSQVGQGESAGSKTSRRQGSSVSQDRDSEGHSEDSERRSESASRN 1617
SR S S+ + + S S+ + S S+ R S RS S SR+
Sbjct: 441 RSRSRSNS----KSKPNLPSESRSRSKSASKTRSRSKSRSR--------SASRSPSRSRS 488
Score = 70.1 bits (170), Expect = 4e-11
Identities = 75/324 (23%), Positives = 124/324 (38%), Gaps = 10/324 (3%)
Query: 2224 LVGQGQSSGPRTSRPRGSSVSQDSDSEGHSEDSERRSGSASRNHHGSAQEQSRDGSRHPR 2283
LV S R S R S S+ HS S RSGS S++ H ++ +SR GSR
Sbjct: 172 LVEDKPGSRRRRSYSRSRSHSRSRSRSRHSRKSRSRSGS-SKSSHSKSRSRSRSGSRSRS 230
Query: 2284 SHHEDRAGHGHSAESSRQSGTHHAENSSGGQAASSHEQARSSAGERHGSHHQQSADSSRH 2343
S + +S + S A S +++ A E+ ++ SR
Sbjct: 231 KSRSRSQSRSRSKKEKSRSPSKEKSRSRSHSAGKSRSKSKDQAEEKIQNNDNVGKPKSRS 290
Query: 2344 SGIGHGQASSAVRDSGHRGSSGSQASDSEGHSEDSDTQSVSAHGQAGPHQQSHQESTRGR 2403
++ S R R + S S G S++ + + ++ +S S
Sbjct: 291 PSRHKSKSKSRSRSQERRVEEEKRGSVSRGRSQEKSLRQSRSRSRSKGGSRSRSRSRSKS 350
Query: 2404 SAGRSGRSGSFLYQVS-THEQSESAHGRT-GTSTGGRQGSHHKQARDSSRHSTSQEGQDT 2461
R GR S S + +S+S R G+ + GS K+ ++ + S S+ +
Sbjct: 351 KDKRKGRKRSREESRSRSRSRSKSERSRKRGSKRDSKAGSSKKKKKEDTDRSQSRSPSRS 410
Query: 2462 I---HGHPGSSSGGRQGSHYEQLVDRSGHSGSHHSHTTSQGRSDASHGHSGSRSASR-QT 2517
+ H S S R+G + + + S + + S S S+SAS+ ++
Sbjct: 411 VSKEREHAKSESSQREGRGESENAGTNQETRSRSRSNSKSKPNLPSESRSRSKSASKTRS 470
Query: 2518 RNDEQSGDGSR---HSGSRHHEAS 2538
R+ +S SR S SR H S
Sbjct: 471 RSKSRSRSASRSPSRSRSRSHSRS 494
Score = 70.1 bits (170), Expect = 4e-11
Identities = 89/351 (25%), Positives = 144/351 (41%), Gaps = 43/351 (12%)
Query: 3110 IRGHPGSSRGGRQGYHHEHSVDSSGHSGSHHSHTTSQGR-SDASRGQSGSRSASRT-TRN 3167
+ PGS R R+ Y S HS + S+ R S SR +SGS +S + +R+
Sbjct: 173 VEDKPGSRR--RRSYSRSRS----------HSRSRSRSRHSRKSRSRSGSSKSSHSKSRS 220
Query: 3168 EEQSGDSSRHSVSRHHEASTHADISRHSQAVQGQSEGSR-RSRRQGSSVSQDSD-SEGHS 3225
+SG SR S+ S S+ ++ E SR RS G S S+ D +E
Sbjct: 221 RSRSGSRSR---SKSRSRSQSRSRSKKEKSRSPSKEKSRSRSHSAGKSRSKSKDQAEEKI 277
Query: 3226 EDSERWSGSASRN---HRGSVQEQSRHGSRHPRSHHEDRAGHGHSADRS-RQSGTRHAET 3281
++++ SR+ H+ + +SR R G S ++S RQS +R
Sbjct: 278 QNNDNVGKPKSRSPSRHKSKSKSRSRSQERRVEEEKRGSVSRGRSQEKSLRQSRSR--SR 335
Query: 3282 SSGGQAASSHEQARSSPGE--RHGSRHQQSADSSRHSGIPRGQASSAVRDSRHWGSSGSQ 3339
S GG + S +++S R SR + + S S R + + RDS+ S +
Sbjct: 336 SKGGSRSRSRSRSKSKDKRKGRKRSREESRSRSRSRSKSERSRKRGSKRDSKAGSSKKKK 395
Query: 3340 ASDSEGHSEESDTQSVSGHGQAGPHQQSHQESARDRSGGRSGRSGSFLYQVSTHEQSESA 3399
D++ S ++SVS +E A+ S R GR S T++++ S
Sbjct: 396 KEDTDRSQSRSPSRSVS----------KEREHAKSESSQREGRGES--ENAGTNQETRS- 442
Query: 3400 HGRTRTSTGRRQGSHHE-QARDSSRHSASQEGQDTIRGHPGSSRRGRQGSH 3449
R+R+++ + E ++R S + R S R R SH
Sbjct: 443 --RSRSNSKSKPNLPSESRSRSKSASKTRSRSKSRSRSASRSPSRSRSRSH 491
Score = 69.7 bits (169), Expect = 6e-11
Identities = 88/336 (26%), Positives = 133/336 (39%), Gaps = 47/336 (13%)
Query: 1813 IRGHPGSSRGGRQGSHYEQSVDSSGHSGSHH-------------SHTTSQERS---DVSR 1856
+ PGS R + S+ S S S H SH+ S+ RS SR
Sbjct: 173 VEDKPGSRR---RRSYSRSRSHSRSRSRSRHSRKSRSRSGSSKSSHSKSRSRSRSGSRSR 229
Query: 1857 GQSGSRSVSR-QTRNEKQSGDGSRHSGSRHHEASSRADSSR---------HSQVGQGQSS 1906
+S SRS SR +++ EK S SR H A S+ + VG+ +S
Sbjct: 230 SKSRSRSQSRSRSKKEKSRSPSKEKSRSRSHSAGKSRSKSKDQAEEKIQNNDNVGKPKSR 289
Query: 1907 GPRTSRNQGSSVSQDSDSQGHSEDSERWSGSASRNHLGSAWEQSRDGSRHPGSHHEDRAG 1966
P SR++ S S+ + E+ +R S S R+ S QSR SR G
Sbjct: 290 SP--SRHKSKSKSRSRSQERRVEEEKRGSVSRGRSQEKSL-RQSRSRSRSKGGSRSRSRS 346
Query: 1967 HGHSADSSRQSGTRHTESSSRGQAASSHEQARSSAGERH---GSHHQLQSADSSRHSGIG 2023
S D + ES SR ++ S E++R +R GS + + D+ R
Sbjct: 347 RSKSKDKRKGRKRSREESRSRSRSRSKSERSRKRGSKRDSKAGSSKKKKKEDTDR----- 401
Query: 2024 HGQASSAVRD-SGHRGYSGSQASDSEGHSEDSDTQSVSAQGKAGPHQQSHKESARGQSGE 2082
Q+ S R S R ++ S++S EG E +++ + +S+ +S E
Sbjct: 402 -SQSRSPSRSVSKEREHAKSESSQREGRGE---SENAGTNQETRSRSRSNSKSKPNLPSE 457
Query: 2083 SSGRSGSFLYQVSTHEQSESTHGQSAPSTGGRQGSH 2118
S RS S + + +S S +PS R SH
Sbjct: 458 SRSRSKS-ASKTRSRSKSRSRSASRSPSR-SRSRSH 491
Score = 69.3 bits (168), Expect = 7e-11
Identities = 100/435 (22%), Positives = 163/435 (37%), Gaps = 59/435 (13%)
Query: 2666 RHSGIGHGQASSAVRDSGHRGYSGSQASDN----EGHSEDSDTQSVSAH-GQAGSHQQSH 2720
R G G++ R SG Y ++ E S Q + + QAG + ++
Sbjct: 75 RDGSYGSGRSGYGYRRSGRDKYGPPTRTEYRLIVENLSSRCSWQDLKDYMRQAG--EVTY 132
Query: 2721 QESARGRSGETSGHSGSFLYQVSTHEQSESSHGWTGPSTRGRQGSRHEQAQDSSRHSASQ 2780
++ +GR E + VS + + G GR+ E S R +
Sbjct: 133 ADAHKGRKNE------GVIEFVSYSDMKRALEKLDGTEVNGRKIRLVEDKPGSRRRRSYS 186
Query: 2781 DGQDTIRGHPGSSRGGRQGYHHEHSVDSSGHSGSHHSHTTSQGRSDA-SRGQSGSRSASR 2839
R H SR + H S SG S S HS + S+ RS + SR +S SRS SR
Sbjct: 187 RS----RSH---SRSRSRSRHSRKSRSRSGSSKSSHSKSRSRSRSGSRSRSKSRSRSQSR 239
Query: 2840 TTRNEEQSGDGSRH-SGSRHHEASTHADISRHS--QAVQG---------------QSEGS 2881
+ +E+S S+ S SR H A S+ + +Q +S+
Sbjct: 240 SRSKKEKSRSPSKEKSRSRSHSAGKSRSKSKDQAEEKIQNNDNVGKPKSRSPSRHKSKSK 299
Query: 2882 RRSRRQGSSVSQD---SDSEGHSED---------SERWSGSASRNHHGSAQEQLRDGSRH 2929
RSR Q V ++ S S G S++ S GS SR+ S + R G +
Sbjct: 300 SRSRSQERRVEEEKRGSVSRGRSQEKSLRQSRSRSRSKGGSRSRSRSRSKSKDKRKGRKR 359
Query: 2930 PRSHQEDRAGHGHSADSSRQSGTRHTQTSSGGQAASSHE----QARSSAGERHGSHHQQS 2985
R R+ ++ SR+ G++ + + + Q+RS +
Sbjct: 360 SREESRSRSRSRSKSERSRKRGSKRDSKAGSSKKKKKEDTDRSQSRSPSRSVSKEREHAK 419
Query: 2986 ADSSRHSGIGHGQASSAVRDSGHRGYSGSQASDN---EGHSEDSDTQSVSAHGQAGSHQQ 3042
++SS+ G G + + +++ R S S++ N E S + ++ S
Sbjct: 420 SESSQREGRGESENAGTNQETRSRSRSNSKSKPNLPSESRSRSKSASKTRSRSKSRSRSA 479
Query: 3043 SHQES-ARGRSGETS 3056
S S +R RS S
Sbjct: 480 SRSPSRSRSRSHSRS 494
Score = 69.3 bits (168), Expect = 7e-11
Identities = 86/359 (23%), Positives = 138/359 (38%), Gaps = 49/359 (13%)
Query: 527 RQGSHHEQSVNRS-----GHSGSHHSH--TTSQGRSDASHGQSGSRSAS-RQTRNEEQSG 578
+ GS +S +RS S S HS + G S +SH +S SRS S ++R++ +S
Sbjct: 176 KPGSRRRRSYSRSRSHSRSRSRSRHSRKSRSRSGSSKSSHSKSRSRSRSGSRSRSKSRSR 235
Query: 579 DGTRHSGSRHHEASSQADSSRHSQVGQGQSSGPRTSRNQGSSVSQDSDSQGHSEDSERWS 638
+R + S + SR G+S S++Q Q++D+ G + S
Sbjct: 236 SQSRSRSKKEKSRSPSKEKSRSRSHSAGKSRS--KSKDQAEEKIQNNDNVGKPK-----S 288
Query: 639 GSASRNHHGSAQEQSRDGSRHPRSHHEDRAGHGHSADSS-RKSGTRHTQNSSSGQAASSH 697
S SR H ++ +SR R G S + S R+S +R S + S
Sbjct: 289 RSPSR-HKSKSKSRSRSQERRVEEEKRGSVSRGRSQEKSLRQSRSRSRSKGGSRSRSRSR 347
Query: 698 EQARSSAGERHGSRHQLQSADSSRHSGTGHGQASSAVRDSGHRGSSGSQATDSEGHSEDS 757
+++ R SR + +S SR S + + + RDS S + D++ S
Sbjct: 348 SKSKDKRKGRKRSREESRSRSRSR-SKSERSRKRGSKRDSKAGSSKKKKKEDTDRSQSRS 406
Query: 758 DTQSVSGHGQAGHHQQSHQESARDRSGERSRRSGSFLYQVSTHKQSESSHGWTGPSTGVR 817
++SVS +E A+ S +R R ES + T T
Sbjct: 407 PSRSVS----------KEREHAKSESSQREGR-------------GESENAGTNQET--- 440
Query: 818 QGSHHEQARDNSRHSASQDGQDTIRGHPGSSRRGRQGSHHEQSVDRSGHSGSHHSHTTS 876
++R NS+ + + R S R R S +S RS SH+ S
Sbjct: 441 ----RSRSRSNSKSKPNLPSESRSRSKSASKTRSRSKS-RSRSASRSPSRSRSRSHSRS 494
Score = 69.3 bits (168), Expect = 7e-11
Identities = 77/340 (22%), Positives = 138/340 (40%), Gaps = 28/340 (8%)
Query: 852 RQGSHHEQSVDRSGHSGSHHSHTTSQGR-SDASRGQSGSRSASRTTRNEEQSRDGSRHSG 910
+ GS +S RS HS + S+ R S SR +SGS S S +++ +SR GSR
Sbjct: 176 KPGSRRRRSYSRS----RSHSRSRSRSRHSRKSRSRSGS-SKSSHSKSRSRSRSGSRSRS 230
Query: 911 SRHHEASSHADISRHSQAGQGQSEGSRTSRRQGSSVSQDSD-SEGHSEDSERWSGSASRN 969
+ S + + + + S G S S+ D +E ++++ SR+
Sbjct: 231 KSRSRSQSRSRSKKEKSRSPSKEKSRSRSHSAGKSRSKSKDQAEEKIQNNDNVGKPKSRS 290
Query: 970 ---HRGSAQEQSRHGSRHPRSHHEDRAGHGHSADSSRQSGTPHAETSSGGQAAS-SHEQA 1025
H+ ++ +SR R G S + S + + + G ++ S S ++
Sbjct: 291 PSRHKSKSKSRSRSQERRVEEEKRGSVSRGRSQEKSLRQSRSRSRSKGGSRSRSRSRSKS 350
Query: 1026 RSSPGERHGSRHQQSADSSRHSGIPRRQASSAVRDSGHWGSSGSQASDSEGHSEESDTQS 1085
+ R SR + + S S R + + RDS S + D++ S ++S
Sbjct: 351 KDKRKGRKRSREESRSRSRSRSKSERSRKRGSKRDSKAGSSKKKKKEDTDRSQSRSPSRS 410
Query: 1086 VSGHGQDGPHQQSHQESARDWSGGRSGRSGSFIYQVSTHEQSESAHGRTRTSTGRRQGSH 1145
VS +E A+ S R GR S T++++ S R+R S + + +
Sbjct: 411 VS----------KEREHAKSESSQREGRGES--ENAGTNQETRS---RSR-SNSKSKPNL 454
Query: 1146 HEQARDSSRHSASQEGQDTIRAHPGSRRGGRQGSH-HEQS 1184
++R S+ ++ + R+ SR R S H +S
Sbjct: 455 PSESRSRSKSASKTRSRSKSRSRSASRSPSRSRSRSHSRS 494
Score = 69.3 bits (168), Expect = 7e-11
Identities = 77/320 (24%), Positives = 115/320 (35%), Gaps = 14/320 (4%)
Query: 1212 GSRSASRQTRKDKQSGDGSRHSGSRHHEAASWADSSRHSQVGQEQSSGSRTSRHQGSSVS 1271
GSR +R S SR SR + S + S HS+ SGSR+ S
Sbjct: 178 GSRRRRSYSRSRSHSRSRSRSRHSRKSRSRSGSSKSSHSKSRSRSRSGSRSRSKSRSRSQ 237
Query: 1272 QDSDSERHSDDSERLSGSASRNHH-GSSREQSRDGSRHPGFHQEDRASHGHSADSSRQSG 1330
S S++ S S SR+H G SR +S+D + D S SR
Sbjct: 238 SRSRSKKEKSRSPSKEKSRSRSHSAGKSRSKSKDQAEEK-IQNNDNVGKPKSRSPSRHKS 296
Query: 1331 THHTESSSHGQAVSSHEQARSSPGERHGSRHQQSADSSRHSGIGHRQASSAVRDSGHR-G 1389
+ S S + V ++ S G +QS SR G ++ S + R G
Sbjct: 297 KSKSRSRSQERRVEEEKRGSVSRGRSQEKSLRQSRSRSRSKGGSRSRSRSRSKSKDKRKG 356
Query: 1390 SSGSQV-----TNSEGHSEDSDTQSVSAHGQAGPHQQSHKESARGQSGESSGRSRSFLYQ 1444
S+ + S SE S + +AG ++ KE S RS S +
Sbjct: 357 RKRSREESRSRSRSRSKSERSRKRGSKRDSKAGSSKKKKKEDTDRSQSRSPSRSVS---K 413
Query: 1445 VSSHEQSEST--HGQTAPSTGGRQGSRHEQARNSSRHSASQDGQDTIRGHPGSSRGGRQG 1502
H +SES+ G+ G ++R++S+ + + R S R
Sbjct: 414 EREHAKSESSQREGRGESENAGTNQETRSRSRSNSKSKPNLPSESRSRSKSASKTRSRSK 473
Query: 1503 SYHEQSVDRSGHSGYHHSHT 1522
S +S RS SH+
Sbjct: 474 S-RSRSASRSPSRSRSRSHS 492
Score = 68.6 bits (166), Expect = 1e-10
Identities = 81/339 (23%), Positives = 126/339 (37%), Gaps = 24/339 (7%)
Query: 1585 KTSRRQGSSVSQDRDSEGHSEDSER-RSESASRNHYGSAREQSRHGSRNPRSHQEDRASH 1643
K R+ S S+ R HS R R SR+ GS++ S H RS R S
Sbjct: 176 KPGSRRRRSYSRSRS---HSRSRSRSRHSRKSRSRSGSSK--SSHSKSRSRSRSGSR-SR 229
Query: 1644 GHSAESSRQSGTRHAETSSGGQAASSQEQARSSPGERHGSRHQQSADSSTDSGTGRRQDS 1703
S S+ E S S+ ++ S+ R S+ Q + G+ +
Sbjct: 230 SKSRSRSQSRSRSKKEKSRSPSKEKSRSRSHSAGKSRSKSKDQAEEKIQNNDNVGKPKSR 289
Query: 1704 SVVGDSGNRGSSGSQASDSEGHSEESDTQSVSAHGQAGPHQQSHQESTRGQSGERSGRSG 1763
S S ++ S S++ E EE SVS +S ++S R + G
Sbjct: 290 S---PSRHKSKSKSRSRSQERRVEEEKRGSVS-------RGRSQEKSLRQSRSRSRSKGG 339
Query: 1764 SFLYQVSTHEQSESAHGRTGPSTGGRQRSRHEQARDSSRHSASQEGQDTIRGHPGSSRGG 1823
S S + + GR R RSR + SR S+ +D+ G S +
Sbjct: 340 SRSRSRSRSKSKDKRKGRKRSREESRSRSRSRSKSERSRKRGSK--RDSKAG--SSKKKK 395
Query: 1824 RQGSHYEQSVDSSGHSGSHHSHTTSQERSDVSRGQSGSRSVSRQTRNEKQSGDGSR---H 1880
++ + QS S H S+ RG+S + +++TR+ +S S+
Sbjct: 396 KEDTDRSQSRSPSRSVSKEREHAKSESSQREGRGESENAGTNQETRSRSRSNSKSKPNLP 455
Query: 1881 SGSRHHEASSRADSSRHSQVGQGQSSGPRTSRNQGSSVS 1919
S SR S+ SR + S P SR++ S S
Sbjct: 456 SESRSRSKSASKTRSRSKSRSRSASRSPSRSRSRSHSRS 494
Score = 67.8 bits (164), Expect = 2e-10
Identities = 77/333 (23%), Positives = 126/333 (37%), Gaps = 27/333 (8%)
Query: 3374 DRSGGRSGRSGSFLYQVSTHEQSESAHGRTRTSTGRRQGSHHEQARDSSRHSASQEGQDT 3433
D+ G R RS S + + +S S H R S S H ++R SR +
Sbjct: 175 DKPGSRRRRSYS-RSRSHSRSRSRSRHSRKSRSRSGSSKSSHSKSRSRSRSGSRS----- 228
Query: 3434 IRGHPGSSRRGRQGSHYEQSVDRSGHSGSHHSHTTSQGRSDASRGQSGSRSASRQTRNDE 3493
R S + R S E+S S SH+ + RS A + +N++
Sbjct: 229 -RSKSRSRSQSRSRSKKEKSRSPSKEKSRSRSHSAGKSRS------KSKDQAEEKIQNND 281
Query: 3494 QSGDGSRHSWSHHHEASTQADSSRHSQSGQGQSAGPRTSRNQGSSVSQDSDSQGHSEDSE 3553
G S S H S S+ + + + R+Q S+ Q S S+ S+
Sbjct: 282 NVGKPKSRSPSRHKSKSKSRSRSQERRVEEEKRGSVSRGRSQEKSLRQ-SRSRSRSK--- 337
Query: 3554 RWSGSASRNHRGSAQEQSRDGSRHPTSHHEDRAGHGHSAESSRQSGTHH--AENSSGGQA 3611
GS SR+ S + R G + R+ +E SR+ G+ SS +
Sbjct: 338 --GGSRSRSRSRSKSKDKRKGRKRSREESRSRSRSRSKSERSRKRGSKRDSKAGSSKKKK 395
Query: 3612 ASSHEQARSSAGERHGSHHQQSADSSRHSGIGHGQASSAVRDSGHRGSSGSQASDSEGHS 3671
++++S + R S ++ A S G G++ +A + R S S +
Sbjct: 396 KEDTDRSQSRSPSRSVSKEREHAKSESSQREGRGESENAGTNQETRSRSRSNSKSKPNLP 455
Query: 3672 EDSDTQSVSAHGQAGPHQQSHQESTRGRSAGRS 3704
+S ++S SA + + +R RSA RS
Sbjct: 456 SESRSRSKSA------SKTRSRSKSRSRSASRS 482
Score = 66.2 bits (160), Expect = 6e-10
Identities = 76/344 (22%), Positives = 127/344 (36%), Gaps = 34/344 (9%)
Query: 2274 QSRDGSRHPRSHHEDRAGHGHSAESSRQSGTHHAENSSGGQAAS-SHEQARSSAGERHGS 2332
+ + GSR RS+ R+ HS SR + + + SG +S S ++RS +G R S
Sbjct: 174 EDKPGSRRRRSYSRSRS---HSRSRSRSRHSRKSRSRSGSSKSSHSKSRSRSRSGSRSRS 230
Query: 2333 HHQQSADSSRHSGIGHGQASSAVRDSGHRGSSGSQASDSEGHSED--SDTQSVSAHGQAG 2390
+ + S S ++ S + S+G S S+ +E+ + +V
Sbjct: 231 KSRSRSQSRSRSKKEKSRSPSKEKSRSRSHSAGKSRSKSKDQAEEKIQNNDNVGKPKSRS 290
Query: 2391 PHQQSHQESTRGRSAGRSGRSGSFLYQVSTHEQSESAHGRTGTSTGGRQGSHHKQARDSS 2450
P + + +R RS R +V ++ + GR S K R S
Sbjct: 291 PSRHKSKSKSRSRSQER---------RVEEEKRGSVSRGR----------SQEKSLRQSR 331
Query: 2451 RHSTSQEGQDTIHGHPGSSSGGRQGSHYEQLVDRSGHSGSHHSHTTSQGRSDASHGHSGS 2510
S S+ G + S R+G + RS S S S+ R +GS
Sbjct: 332 SRSRSKGGSRSRSRSRSKSKDKRKGRKRSREESRS-RSRSRSKSERSRKRGSKRDSKAGS 390
Query: 2511 RSASRQTRNDEQSGDGSRHSGSRHHEASSRADSSGHSQVGQGQSEGPRTSRNWGSSFSQD 2570
++ D S S+ E A S + G+G+SE T++ S +
Sbjct: 391 SKKKKKEDTDRSQSRSPSRSVSKERE---HAKSESSQREGRGESENAGTNQETRSRSRSN 447
Query: 2571 SDSQGHSEDSERWSGSASRNHHGSAQEQLRDGSRHP-----RSH 2609
S S+ + R ++ ++ + R SR P RSH
Sbjct: 448 SKSKPNLPSESRSRSKSASKTRSRSKSRSRSASRSPSRSRSRSH 491
Score = 65.9 bits (159), Expect = 8e-10
Identities = 84/378 (22%), Positives = 140/378 (37%), Gaps = 44/378 (11%)
Query: 1052 RQASSAVRDSGHWGSSGSQA------SDSEGHSEESDTQSVSGHG----QDGPHQQSHQE 1101
RQA H G SD + E+ D V+G +D P + +
Sbjct: 125 RQAGEVTYADAHKGRKNEGVIEFVSYSDMKRALEKLDGTEVNGRKIRLVEDKPGSRRRRS 184
Query: 1102 SARDWSGGRS-----------GRSGSFIYQVSTHEQSES---AHGRTRTSTGRRQGSHHE 1147
+R S RS RSGS S+H +S S + R+R+ + R S
Sbjct: 185 YSRSRSHSRSRSRSRHSRKSRSRSGS---SKSSHSKSRSRSRSGSRSRSKSRSRSQSRSR 241
Query: 1148 QARDSSRHSASQEGQDTIRAHPGSRRGGRQGSHHEQSVDRSGHSGSHHSHTTSQGRSDAS 1207
++ SR + ++ + R+H + + E+ + + + G S + S+ +S +
Sbjct: 242 SKKEKSRSPSKEKSRS--RSHSAGKSRSKSKDQAEEKIQNNDNVGKPKSRSPSRHKSKS- 298
Query: 1208 HGQSGSRSASRQTRKDKQSG--------DGSRHSGSRHHEAASWADSSRHSQVGQEQSSG 1259
+S SRS R+ ++K+ R S SR SR +++ G
Sbjct: 299 --KSRSRSQERRVEEEKRGSVSRGRSQEKSLRQSRSRSRSKGGSRSRSRSRSKSKDKRKG 356
Query: 1260 SRTSRHQGSSVSQD-SDSERHSDDSERLSGSASRNHHGSSREQSRDGSRHPGFHQEDRAS 1318
+ SR + S S+ S SER + A + + R SR P
Sbjct: 357 RKRSREESRSRSRSRSKSERSRKRGSKRDSKAGSSKKKKKEDTDRSQSRSPSRSVSKERE 416
Query: 1319 HGHSADSSRQSGTHHTESSSHGQAVSSHEQ--ARSSPGERHGSRHQQSADSSRHSGIGHR 1376
H S S R+ G +E++ Q S + ++S P SR + + S S R
Sbjct: 417 HAKSESSQRE-GRGESENAGTNQETRSRSRSNSKSKPNLPSESRSRSKSASKTRSRSKSR 475
Query: 1377 QASSAVRDSGHRGSSGSQ 1394
S++ S R S S+
Sbjct: 476 SRSASRSPSRSRSRSHSR 493
Score = 65.5 bits (158), Expect = 1e-09
Identities = 96/384 (25%), Positives = 149/384 (38%), Gaps = 59/384 (15%)
Query: 2418 VSTHEQSESAHGRTGTSTGGRQGSHHKQARDSSRHSTSQEGQDTIHGHPGSSSGGRQGSH 2477
VS + + GT GR+ + S R + + H S S R H
Sbjct: 148 VSYSDMKRALEKLDGTEVNGRKIRLVEDKPGSRRRRSYSRSRS----HSRSRSRSR---H 200
Query: 2478 YEQLVDRSGHSGSHHSHTTSQGRSDA-SHGHSGSRSASRQTRNDEQSGDGSRHSGSRHHE 2536
+ RSG S S HS + S+ RS + S S SRS SR E+S S+ +
Sbjct: 201 SRKSRSRSGSSKSSHSKSRSRSRSGSRSRSKSRSRSQSRSRSKKEKSRSPSKE------K 254
Query: 2537 ASSRADSSGHSQ----------------VGQGQSEGPRTSRNWGSSFSQDSDSQGHSEDS 2580
+ SR+ S+G S+ VG+ +S P SR+ S S+ + E+
Sbjct: 255 SRSRSHSAGKSRSKSKDQAEEKIQNNDNVGKPKSRSP--SRHKSKSKSRSRSQERRVEEE 312
Query: 2581 ERWSGSASRNHHGSAQEQLRDGSRHPRSHQEDRA-GHGHSADSSRQSGTRHTQTSSGGQA 2639
+R GS SR S ++ LR RS R+ S ++ G + ++ S
Sbjct: 313 KR--GSVSRGR--SQEKSLRQSRSRSRSKGGSRSRSRSRSKSKDKRKGRKRSREES---R 365
Query: 2640 ASSHEQARSSAGERHGSHHQQSADSS---RHSGIGHGQASSAVRD-SGHRGYSGSQASDN 2695
+ S +++S + GS A SS + Q+ S R S R ++ S++S
Sbjct: 366 SRSRSRSKSERSRKRGSKRDSKAGSSKKKKKEDTDRSQSRSPSRSVSKEREHAKSESSQR 425
Query: 2696 EGHSEDSDTQSVSAHGQAGSHQQSHQESARGRSGETSGHSGSFLYQVSTHEQSESSHGWT 2755
EG E + AG++Q++ +R RS S + L S +S +
Sbjct: 426 EGRGESEN---------AGTNQETR---SRSRSNSKSKPN---LPSESRSRSKSASKTRS 470
Query: 2756 GPSTRGRQGSRHEQAQDSSRHSAS 2779
+R R SR S HS S
Sbjct: 471 RSKSRSRSASRSPSRSRSRSHSRS 494
Score = 65.5 bits (158), Expect = 1e-09
Identities = 69/320 (21%), Positives = 111/320 (34%), Gaps = 10/320 (3%)
Query: 888 GSRSASRTTRNEEQSRDGSRHSGSRHHEASSHADISRHSQAGQGQSEGSRTSRRQGSSVS 947
GSR +R+ SR SR SR + S + S HS++ GSR+ + S
Sbjct: 178 GSRRRRSYSRSRSHSRSRSRSRHSRKSRSRSGSSKSSHSKSRSRSRSGSRSRSKSRSRSQ 237
Query: 948 QDSDSEGHSEDSERWSGSASRNHRGSAQEQSRHGSRHPRSHHEDRAGHGHSADSSRQSGT 1007
S S+ S S SR+H + + D G S SR
Sbjct: 238 SRSRSKKEKSRSPSKEKSRSRSHSAGKSRSKSKDQAEEKIQNNDNVGKPKSRSPSRHKSK 297
Query: 1008 PHAETSSGGQAASSHEQARSSPGERHGSRHQQSADSSRHSGIPRRQASSAVRDSGHWGSS 1067
+ + S + ++ S G +QS SR G R ++ S R
Sbjct: 298 SKSRSRSQERRVEEEKRGSVSRGRSQEKSLRQSRSRSRSKGGSRSRSRS--RSKSKDKRK 355
Query: 1068 GSQASDSEGHS-----EESDTQSVSGHGQDGPHQQSHQESARDWSGGRSGRSGSFIYQVS 1122
G + S E S +S+ G +D S ++ D +S + +
Sbjct: 356 GRKRSREESRSRSRSRSKSERSRKRGSKRDSKAGSSKKKKKEDTDRSQSRSPSRSVSKER 415
Query: 1123 THEQSESA--HGRTRTSTGRRQGSHHEQARDSSRHSASQEGQDTIRAHPGSRRGGRQGSH 1180
H +SES+ GR + ++R +S+ + + R+ S+ R S
Sbjct: 416 EHAKSESSQREGRGESENAGTNQETRSRSRSNSKSKPNLPSESRSRSKSASKTRSRSKS- 474
Query: 1181 HEQSVDRSGHSGSHHSHTTS 1200
+S RS SH+ S
Sbjct: 475 RSRSASRSPSRSRSRSHSRS 494
Score = 65.1 bits (157), Expect = 1e-09
Identities = 76/339 (22%), Positives = 121/339 (35%), Gaps = 38/339 (11%)
Query: 3434 IRGHPGSSRRGRQGSHYEQSVDRSGHSGSHHSHTTSQGR-SDASRGQSGSRSASRQTRND 3492
+ PGS RR RS HS + S+ R S SR +SGS S S +++
Sbjct: 173 VEDKPGSRRR------------RSYSRSRSHSRSRSRSRHSRKSRSRSGS-SKSSHSKSR 219
Query: 3493 EQSGDGSRHSWSHHHEASTQADSSRHSQSGQGQSAGPRTSRNQGSSVSQDSDS-----QG 3547
+S GSR + +++ S + + S + G S S+ D Q
Sbjct: 220 SRSRSGSRSRSKSRSRSQSRSRSKKEKSRSPSKEKSRSRSHSAGKSRSKSKDQAEEKIQN 279
Query: 3548 HSEDSERWSGSASRNHRGSAQEQSRDGSRHPTSHHEDRAGHGHSAESSRQSGTHHAENSS 3607
+ + S S SR H+ ++ +SR R G S E S + + +
Sbjct: 280 NDNVGKPKSRSPSR-HKSKSKSRSRSQERRVEEEKRGSVSRGRSQEKSLRQSRSRSRSKG 338
Query: 3608 GGQAAS---------------SHEQARSSAGERHGSHHQQSADSSRHSGIGHGQASSAVR 3652
G ++ S S E++RS + R S + S R S G + +
Sbjct: 339 GSRSRSRSRSKSKDKRKGRKRSREESRSRSRSRSKSERSRKRGSKRDSKAGSSKKKK--K 396
Query: 3653 DSGHRGSSGSQASDSEGHSEDSDTQSVSAHGQAGPHQQSHQESTRGRSAGRSGRSGSFLY 3712
+ R S S + E + ++S G+ + TR RS S +S L
Sbjct: 397 EDTDRSQSRSPSRSVSKEREHAKSESSQREGRGESENAGTNQETRSRSRSNS-KSKPNLP 455
Query: 3713 QVSTHEQSESAHGRAGPSTGGRQGSRHEQARDSSRHSAS 3751
S ++ R+ + R SR S HS S
Sbjct: 456 SESRSRSKSASKTRSRSKSRSRSASRSPSRSRSRSHSRS 494
Score = 65.1 bits (157), Expect = 1e-09
Identities = 76/312 (24%), Positives = 124/312 (39%), Gaps = 28/312 (8%)
Query: 259 RSRSSDGKSSSQVNRSRHENTSQVPLQESRTRKRRGSRVSQDRDSEGHSEDSERHSGSAS 318
RSRS KSS +RSR + S R+R + SR S+ S S S
Sbjct: 205 RSRSGSSKSSHSKSRSRSRSGS-------RSRSKSRSRSQSRSRSKKEKSRSPSKEKSRS 257
Query: 319 RNHH-GSAWEQSRDGSRHPRSHDEDRASHGHSADSSRQSGTRHAETSSRGQTASSHEQAR 377
R+H G + +S+D + + + D S SR +++ SR Q E+ R
Sbjct: 258 RSHSAGKSRSKSKDQAEE-KIQNNDNVGKPKSRSPSRHKS--KSKSRSRSQERRVEEEKR 314
Query: 378 SSPGERHGSGHQQSADSSRHSATGRGQASSAVSDRGHRGSSGSQASDSEGHSENSDTQSV 437
S G ++S SR + +G + S R S S++ D + S +S
Sbjct: 315 GSVS--RGRSQEKSLRQSRSRSRSKGGSRS-------RSRSRSKSKDKRKGRKRSREES- 364
Query: 438 SGHGKAGLRQQSHQESTRGRSGERSGRSGSSLYQVSTHEQPDSAHGRTGTSTGGRQGSHH 497
++ R +S E +R R +R ++GSS + E D + R+ + + ++ H
Sbjct: 365 ----RSRSRSRSKSERSRKRGSKRDSKAGSS--KKKKKEDTDRSQSRSPSRSVSKEREHA 418
Query: 498 EQARDSSRHSASQEGQDTIRGHPGSSRGGRQGSHHEQSVNRSGHSGSHHSHTTSQGRS-D 556
+ E T + SR + + S +RS + + + S+ RS
Sbjct: 419 KSESSQREGRGESENAGTNQETRSRSRSNSKSKPNLPSESRSRSKSASKTRSRSKSRSRS 478
Query: 557 ASHGQSGSRSAS 568
AS S SRS S
Sbjct: 479 ASRSPSRSRSRS 490
Score = 63.9 bits (154), Expect = 3e-09
Identities = 84/353 (23%), Positives = 135/353 (38%), Gaps = 42/353 (11%)
Query: 2844 EEQSGDGSRHSGSRHHEASTHADISRHSQAVQGQSEGSRRSR-RQGSSVSQDSDSEGHSE 2902
E++ G R S SR S SRHS R+SR R GSS S S S S
Sbjct: 174 EDKPGSRRRRSYSRSRSHSRSRSRSRHS----------RKSRSRSGSSKSSHSKSRSRSR 223
Query: 2903 DSERWSGSASRNHHGSAQEQLRDGSRHPRSHQEDRAGH--GHSADSSRQSGTRHTQTSSG 2960
R S S SR+ S ++ SR P + H G S S+ Q +
Sbjct: 224 SGSR-SRSKSRSRSQSRSRSKKEKSRSPSKEKSRSRSHSAGKSRSKSKDQAEEKIQNNDN 282
Query: 2961 GQAASSHEQARSSAGERHGSHHQQS-ADSSRHSGIGHGQASS-AVRDSGHRGYS-GSQAS 3017
S +R + + S Q+ + + + G++ ++R S R S G S
Sbjct: 283 VGKPKSRSPSRHKSKSKSRSRSQERRVEEEKRGSVSRGRSQEKSLRQSRSRSRSKGGSRS 342
Query: 3018 DNEGHSEDSDTQSVSAHGQAGSHQQSHQESARGRSGETSGHSGSFLYQVSTHEQSESSHG 3077
+ S+ D + G+ S ++S S E S GS + +S G
Sbjct: 343 RSRSRSKSKDKRK----GRKRSREESRSRSRSRSKSERSRKRGS---------KRDSKAG 389
Query: 3078 WTGPSTRGRQGSRHEQAQDSSRHSASQYGQDTIRGHPGSSRGGRQGYHHEHSVDSSGHSG 3137
+ ++ + Q++ SR + + R H S R+G + ++ +
Sbjct: 390 --SSKKKKKEDTDRSQSRSPSRSVSKE------REHAKSESSQREGRGESENAGTNQETR 441
Query: 3138 SHHSHTTSQGRSDASRGQSGSRSASRT-TRNEEQSGDSSR---HSVSRHHEAS 3186
S + + S +S S+SAS+T +R++ +S +SR S SR H S
Sbjct: 442 SRSRSNSKSKPNLPSESRSRSKSASKTRSRSKSRSRSASRSPSRSRSRSHSRS 494
Score = 63.9 bits (154), Expect = 3e-09
Identities = 80/344 (23%), Positives = 117/344 (34%), Gaps = 30/344 (8%)
Query: 2821 SQGRSDASRGQSGSRSASRTTRNEEQSGDGSRHSGSRHHEASTHADISRHSQAVQGQSEG 2880
S+ R SR +S SRS SR+ SR S SR + + SR +S
Sbjct: 179 SRRRRSYSRSRSHSRSRSRSRH--------SRKSRSRSGSSKSSHSKSRSRSRSGSRSRS 230
Query: 2881 SRRSRRQGSSVSQDSDSEGHSEDSERWSGSASRNHHGSAQEQLRDGSRHPRSHQEDRAGH 2940
RSR Q S S+ S S++ R SR+H + D G
Sbjct: 231 KSRSRSQSRSRSKKEKSRSPSKEKSR-----SRSHSAGKSRSKSKDQAEEKIQNNDNVGK 285
Query: 2941 GHSADSSRQSGTRHTQTSSGGQAASSHEQARSSAGERHGSHHQQSADSSRHSGIGHGQAS 3000
S SR +++ S + ++ S G +QS SR G ++
Sbjct: 286 PKSRSPSRHKSKSKSRSRSQERRVEEEKRGSVSRGRSQEKSLRQSRSRSRSKGGSRSRSR 345
Query: 3001 SAVRDSGHRGYSGSQASDNEGHSEDSDTQSVSAHGQAGSHQQSHQESARGRSGETSGHSG 3060
S + R G + S E S + GS + S S++ + E + S
Sbjct: 346 SRSKSKDKR--KGRKRSREESRSRSRSRSKSERSRKRGSKRDSKAGSSKKKKKEDTDRSQ 403
Query: 3061 SFLYQVSTHEQSESSHGWTGPSTRGRQGSRHEQAQDSSRHSASQYGQDTIRGHPGSSRGG 3120
S S E H + S R +G + S S+ + P SR
Sbjct: 404 S--RSPSRSVSKEREHAKSESSQREGRGESENAGTNQETRSRSRSNSKSKPNLPSESR-- 459
Query: 3121 RQGYHHEHSVDSSGHSGSHHSHTTSQGRSDASRGQSGSRSASRT 3164
S + S + S+ RS ASR S SRS S +
Sbjct: 460 ----------SRSKSASKTRSRSKSRSRS-ASRSPSRSRSRSHS 492
Score = 61.6 bits (148), Expect = 2e-08
Identities = 81/352 (23%), Positives = 133/352 (37%), Gaps = 39/352 (11%)
Query: 1871 EKQSGDGSRHSGSRHHEASSRADSSRHSQVGQGQSSGPRTSRNQGSSVSQDSDSQGHSED 1930
E + G R S SR S SRHS+ + +S GSS S S S+ S
Sbjct: 174 EDKPGSRRRRSYSRSRSHSRSRSRSRHSRKSRSRS---------GSSKSSHSKSRSRSRS 224
Query: 1931 SERWSGSASRNHLGSAWEQSRDGSRHPGSHHEDRAGH--GHSADSSRQSGTRHTESSSRG 1988
R S S SR+ S ++ SR P H G S S+ +++
Sbjct: 225 GSR-SRSKSRSRSQSRSRSKKEKSRSPSKEKSRSRSHSAGKSRSKSKDQAEEKIQNNDNV 283
Query: 1989 QAASSHEQARSSAGERHGSHHQLQSADSSRHSGIGHGQASS-AVRDSGHRGYS-GSQASD 2046
S +R + + S Q + + + + G++ ++R S R S G S
Sbjct: 284 GKPKSRSPSRHKSKSKSRSRSQERRVEEEKRGSVSRGRSQEKSLRQSRSRSRSKGGSRSR 343
Query: 2047 SEGHSEDSDTQSVSAQGKAGPHQQSHKESARGQSGESSGRSGSFLYQVSTHEQSESTHGQ 2106
S S+ D + +G+ ++S S E S + GS + +S G
Sbjct: 344 SRSRSKSKDKR----KGRKRSREESRSRSRSRSKSERSRKRGS---------KRDSKAGS 390
Query: 2107 SAPSTGGRQGSHYDQAQDSSRHSASQEGQDTIRGHPGPSRGGRQGSHQEQSVDRSGHSGS 2166
S ++ + Q++ SR S S+E R H R+G + ++ + + S
Sbjct: 391 SKKKK--KEDTDRSQSRSPSR-SVSKE-----REHAKSESSQREGRGESENAGTNQETRS 442
Query: 2167 HHSHTTSQGRSDASRGQSGSRSASR-KTYDKEQSGDGSR---HSGSHHHEAS 2214
+ + S +S S+SAS+ ++ K +S SR S S H S
Sbjct: 443 RSRSNSKSKPNLPSESRSRSKSASKTRSRSKSRSRSASRSPSRSRSRSHSRS 494
Score = 61.2 bits (147), Expect = 2e-08
Identities = 83/348 (23%), Positives = 130/348 (37%), Gaps = 68/348 (19%)
Query: 735 RDSGHRGSSGSQATDSEGHSEDSDTQSVSGHGQAGHHQQSHQES-ARDRSGERSRRSGSF 793
R S R S S++ HS S ++S G + SH +S +R RSG RSR
Sbjct: 182 RRSYSRSRSHSRSRSRSRHSRKSRSRS-------GSSKSSHSKSRSRSRSGSRSRSK--- 231
Query: 794 LYQVSTHKQSESSHGWTGPSTGVRQGSHHEQARDNSRHSASQDGQDTIRGHPGSSRRGRQ 853
+ +S+S R S E++R S+ + R H R +
Sbjct: 232 -----SRSRSQS-----------RSRSKKEKSRSPSKEKSRS------RSHSAGKSRSKS 269
Query: 854 GSHHEQSVDRSGHSGSHHSHTTSQGRSDASRGQSGSRSASRTT---------------RN 898
E+ + + + G S + S R +S S+S SR+ R+
Sbjct: 270 KDQAEEKIQNNDNVGKPKSRSPS-------RHKSKSKSRSRSQERRVEEEKRGSVSRGRS 322
Query: 899 EE----QSRDGSRHSGSRHHEASSHADISRHSQAGQGQSEGSRTSRRQGSSVSQDSDSEG 954
+E QSR SR G + S + S+ + G+ +S SR + S S+ S G
Sbjct: 323 QEKSLRQSRSRSRSKGGSRSRSRSRSK-SKDKRKGRKRSREESRSRSRSRSKSERSRKRG 381
Query: 955 HSEDSERWSGSASRNHRGSAQEQSRHGSR-------HPRSHHEDRAGHGHSADSSRQSGT 1007
DS+ S S + + + QSR SR H +S R G G S ++ T
Sbjct: 382 SKRDSKAGS-SKKKKKEDTDRSQSRSPSRSVSKEREHAKSESSQREGRGESENAGTNQET 440
Query: 1008 PHAETSSGGQAASSHEQARSSPGERHGSRHQQSADSSRHSGIPRRQAS 1055
S+ + ++RS +R + + S S P R S
Sbjct: 441 RSRSRSNSKSKPNLPSESRSRSKSASKTRSRSKSRSRSASRSPSRSRS 488
Score = 60.5 bits (145), Expect = 3e-08
Identities = 79/339 (23%), Positives = 128/339 (37%), Gaps = 38/339 (11%)
Query: 2786 IRGHPGSSRGGRQGYHHEHSVDSSGHSGSHHSHTTSQGR-SDASRGQSGSRSASRTTRNE 2844
+ PGS R R+ Y S HS + S+ R S SR +SGS S S +++
Sbjct: 173 VEDKPGSRR--RRSYSRSRS----------HSRSRSRSRHSRKSRSRSGS-SKSSHSKSR 219
Query: 2845 EQSGDGSRHSGSRHHEASTHADISRHSQAVQGQSEGSR-RSRRQGSSVSQDSD-SEGHSE 2902
+S GSR S S+ S S+ ++ E SR RS G S S+ D +E +
Sbjct: 220 SRSRSGSR-SRSKSRSRSQSRSRSKKEKSRSPSKEKSRSRSHSAGKSRSKSKDQAEEKIQ 278
Query: 2903 DSERWSGSASRN---HHGSAQEQLRDGSRHPRSHQEDRAGHGHSADSSRQSGTRHTQTSS 2959
+++ SR+ H ++ + R R + G S + S + +++
Sbjct: 279 NNDNVGKPKSRSPSRHKSKSKSRSRSQERRVEEEKRGSVSRGRSQEKSLRQSRSRSRSKG 338
Query: 2960 GGQAAS---------------SHEQARSSAGERHGSHHQQSADSSRHSGIGHGQASSAVR 3004
G ++ S S E++RS + R S + S R S G + +
Sbjct: 339 GSRSRSRSRSKSKDKRKGRKRSREESRSRSRSRSKSERSRKRGSKRDSKAGSSKKKK--K 396
Query: 3005 DSGHRGYSGSQASDNEGHSEDSDTQSVSAHGQAGSHQQSHQESARGRSGETSGHSGSFLY 3064
+ R S S + E + ++S G+ S + R RS ++ S L
Sbjct: 397 EDTDRSQSRSPSRSVSKEREHAKSESSQREGRGESENAGTNQETRSRS-RSNSKSKPNLP 455
Query: 3065 QVSTHEQSESSHGWTGPSTRGRQGSRHEQAQDSSRHSAS 3103
S +S + +R R SR S HS S
Sbjct: 456 SESRSRSKSASKTRSRSKSRSRSASRSPSRSRSRSHSRS 494
Score = 60.5 bits (145), Expect = 3e-08
Identities = 75/342 (21%), Positives = 127/342 (37%), Gaps = 34/342 (9%)
Query: 3033 AHGQAGSHQQSHQESARGRSGETSGHSGSFLYQVSTHEQSESSHGWTGPSTRGRQGSRHE 3092
++ ++ SH +S S R + S S+H +S S R R GSR
Sbjct: 184 SYSRSRSHSRSRSRSRHSRKSRSRSGSSK-----SSHSKSRS---------RSRSGSRSR 229
Query: 3093 QAQDSSRHSASQYGQDTIRG---HPGSSRGGRQGYHHEHSVDSSGHSGSHHSHTTSQGRS 3149
S S S+ ++ R SR G S D + ++ +
Sbjct: 230 SKSRSRSQSRSRSKKEKSRSPSKEKSRSRSHSAGKSRSKSKDQAEEKIQNNDNVGKPKSR 289
Query: 3150 DASRGQSGSRSASRTTRNEEQSGDSSRHSVSRHHEASTHADISRHSQAVQGQSEGSRRSR 3209
SR +S S+S SR+ E + + R SVSR SR + +S+G RSR
Sbjct: 290 SPSRHKSKSKSRSRS--QERRVEEEKRGSVSRGRSQEKSLRQSRS----RSRSKGGSRSR 343
Query: 3210 RQGSSVSQDSDSEGHSEDSERWSGSASRNHRGSVQEQSRHGSRHPRSHHEDRAGHGHSAD 3269
+ S S+D +G E S S SR+ S + + R R ++ G S
Sbjct: 344 SRSRSKSKDK-RKGRKRSREE-SRSRSRSRSKSERSRKRGSKRDSKA--------GSSKK 393
Query: 3270 RSRQSGTRHAETSSGGQAASSHEQARSSPGERHGSRHQQSADSSRHSGIPRGQASSAVRD 3329
+ ++ R S + E A+S +R G ++A +++ + R +++S +
Sbjct: 394 KKKEDTDRSQSRSPSRSVSKEREHAKSESSQREGRGESENAGTNQETR-SRSRSNSKSKP 452
Query: 3330 SRHWGSSGSQASDSEGHSEESDTQSVSGHGQAGPHQQSHQES 3371
+ S S S+ S + + +SH S
Sbjct: 453 NLPSESRSRSKSASKTRSRSKSRSRSASRSPSRSRSRSHSRS 494
Score = 60.5 bits (145), Expect = 3e-08
Identities = 82/338 (24%), Positives = 131/338 (38%), Gaps = 36/338 (10%)
Query: 2642 SHEQARSSAGERHGSHHQQSADSSRHSGIGHGQASSAVRDSGHRGYSGSQA-SDNEGHSE 2700
SH ++RS + RH + + SS+ S H ++ S R SG R S S++ S + S+
Sbjct: 190 SHSRSRSRS--RHSRKSRSRSGSSKSS---HSKSRSRSR-SGSRSRSKSRSRSQSRSRSK 243
Query: 2701 DSDTQSVSAHGQAGSHQQSHQESARGRSGETSGHSGSFLYQVSTHEQSESSHGWTGPSTR 2760
++S S +E +R RS Q Q+ + G +
Sbjct: 244 KEKSRSPS------------KEKSRSRSHSAGKSRSKSKDQAEEKIQNNDNVG----KPK 287
Query: 2761 GRQGSRHEQAQDSSRHSASQDGQDTIRGHPGSSRGGRQGYHHEHSVDSSGHSGSHHSHTT 2820
R SRH+ S S + ++ RG SRG Q S S G S +
Sbjct: 288 SRSPSRHKSKSKSRSRSQERRVEEEKRG--SVSRGRSQEKSLRQSRSRSRSKGGSRSRSR 345
Query: 2821 SQGRS-DASRGQSGSRSASRTTRNEEQSGDGSRHSGSRHHEASTHADISRHSQAVQGQSE 2879
S+ +S D +G+ SR SR+ + SR GS+ S+ + + + E
Sbjct: 346 SRSKSKDKRKGRKRSREESRSRSRSRSKSERSRKRGSKRD--------SKAGSSKKKKKE 397
Query: 2880 GSRRSRRQGSSVSQDSDSEGHSEDSERWSGSASRNHHGSAQEQLRDGSRHPRSHQEDRAG 2939
+ RS+ + S S + E +S + G + G+ QE R SR + +
Sbjct: 398 DTDRSQSRSPSRSVSKEREHAKSESSQREGRGESENAGTNQE-TRSRSRSNSKSKPNLPS 456
Query: 2940 HGHSADSSRQSGTRHTQTSSGGQAASSHEQARSSAGER 2977
S S S TR S A+ S ++RS + R
Sbjct: 457 ESRSRSKS-ASKTRSRSKSRSRSASRSPSRSRSRSHSR 493
Score = 55.8 bits (133), Expect = 8e-07
Identities = 74/280 (26%), Positives = 111/280 (39%), Gaps = 32/280 (11%)
Query: 3759 RGHPGSRRGGRQGSYHEQSVDRSGHSGSHHSHTTSQGRSDA-SHGQSGSRSASRETRNEE 3817
R H SR R + +S RSG S S HS + S+ RS + S +S SRS SR +E
Sbjct: 189 RSHSRSRSRSR---HSRKSRSRSGSSKSSHSKSRSRSRSGSRSRSKSRSRSQSRSRSKKE 245
Query: 3818 QSGDGSRH-SGSRHHEAST-------QADSSRHSQSGQGESAGSRRSRRQGSSVSQDSDS 3869
+S S+ S SR H A QA+ + G+ SR + S S+
Sbjct: 246 KSRSPSKEKSRSRSHSAGKSRSKSKDQAEEKIQNNDNVGKPKSRSPSRHKSKSKSRSRSQ 305
Query: 3870 EAYPEDSER--------------RSESASRNHHGS-SREQSRDGSRHPGSSHRDTASHVQ 3914
E E+ +R +S S SR+ GS SR +SR S+ + + +
Sbjct: 306 ERRVEEEKRGSVSRGRSQEKSLRQSRSRSRSKGGSRSRSRSRSKSKDKRKGRKRSREESR 365
Query: 3915 SSPVQSDSSTAKEHGHFSSLSQDSAYHSGIQSR--GSPHSSSSYHYQSEGTERQKGQSGL 3972
S +S S + E +DS S + + + S S +S ER+ +S
Sbjct: 366 S---RSRSRSKSERSRKRGSKRDSKAGSSKKKKKEDTDRSQSRSPSRSVSKEREHAKSES 422
Query: 3973 VWRHGSYGSADYDYGESGFRHSQHGSVSYNSNPVVFKERS 4012
R G S + + S+ S S + P + RS
Sbjct: 423 SQREGRGESENAGTNQETRSRSRSNSKSKPNLPSESRSRS 462
Score = 45.8 bits (107), Expect = 9e-04
Identities = 47/170 (27%), Positives = 66/170 (38%), Gaps = 11/170 (6%)
Query: 3805 GSRSASRETRNEEQSGDGSRHSGSRHHEASTQADSSRHSQSGQGESAGSRRSRRQGSSVS 3864
GSR +R+ S SR SR + + + S HS+S +GSR + S
Sbjct: 178 GSRRRRSYSRSRSHSRSRSRSRHSRKSRSRSGSSKSSHSKSRSRSRSGSRSRSKSRSRSQ 237
Query: 3865 QDSDSEAYPEDSERRSESASRNHH-GSSREQSRDGSRHPGSSHRDTASHVQSSPVQSDSS 3923
S S+ S + +S SR+H G SR +S+D + ++ + SP S
Sbjct: 238 SRSRSKKEKSRSPSKEKSRSRSHSAGKSRSKSKDQAEEKIQNNDNVGKPKSRSP-----S 292
Query: 3924 TAKEHGHFSSLSQDSAYHS---GIQSRGSPHSSSSYHYQSEGTERQKGQS 3970
K S SQ+ G SRG S QS R KG S
Sbjct: 293 RHKSKSKSRSRSQERRVEEEKRGSVSRGRSQEKSL--RQSRSRSRSKGGS 340
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.301 0.115 0.323
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 170,850,288
Number of Sequences: 37866
Number of extensions: 8693886
Number of successful extensions: 120531
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 299
Number of HSP's successfully gapped in prelim test: 1249
Number of HSP's that attempted gapping in prelim test: 37005
Number of HSP's gapped (non-prelim): 30365
length of query: 4061
length of database: 18,247,518
effective HSP length: 123
effective length of query: 3938
effective length of database: 13,590,000
effective search space: 53517420000
effective search space used: 53517420000
T: 11
A: 40
X1: 17 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 43 (21.8 bits)
S2: 72 (32.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.