Search of human proteins with 5730009

Search of human proteins with 5730009

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|5730009 ret finger protein [Homo sapiens]
         (513 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|5730009 ret finger protein [Homo sapiens]                         1070   0.0  
gi|25777698 tripartite motif-containing 39 isoform 2 [Homo sapiens]   362   e-100
gi|21630277 tripartite motif-containing 11 [Homo sapiens]             361   e-99 
gi|4557743 Mediterranean fever protein [Homo sapiens]                 350   2e-96
gi|25777696 tripartite motif-containing 39 isoform 1 [Homo sapiens]   348   5e-96
gi|15208660 tripartite motif protein 21 [Homo sapiens]                332   5e-91
gi|44680122 tripartite motif-containing 7 isoform 1 [Homo sapiens]    330   1e-90
gi|37622899 ring finger protein 137 [Homo sapiens]                    327   2e-89
gi|68160933 tripartite motif-containing 17 isoform 1 [Homo sapiens]   315   6e-86
gi|7705825 tripartite motif-containing 17 isoform 1 [Homo sapiens]    315   6e-86
gi|112421127 tripartite motif-containing 58 [Homo sapiens]            298   1e-80
gi|68160935 tripartite motif-containing 17 isoform 2 [Homo sapiens]   287   1e-77
gi|5454014 tripartite motif-containing 38 [Homo sapiens]              287   1e-77
gi|157743261 tripartite motif-containing 75 [Homo sapiens]            279   4e-75
gi|157426898 tripartite motif-containing 10 isoform 1 [Homo sapi...   276   4e-74
gi|22749269 ring finger protein 129 [Homo sapiens]                    268   9e-72
gi|18079262 tripartite motif-containing 6 isoform 2 [Homo sapiens]    268   1e-71
gi|51477692 tripartite motif-containing 6 isoform 1 [Homo sapiens]    268   1e-71
gi|42516572 tripartite motif-containing 41 isoform 1 [Homo sapiens]   259   5e-69
gi|31542779 tripartite motif family-like 1 [Homo sapiens]             255   8e-68
gi|15011941 tripartite motif protein TRIM4 isoform beta [Homo sa...   251   8e-67
gi|149193331 tripartite motif protein 15 [Homo sapiens]               249   3e-66
gi|14719418 tripartite motif protein TRIM5 isoform alpha [Homo s...   244   1e-64
gi|14670266 tripartite motif protein TRIM4 isoform alpha [Homo s...   241   9e-64
gi|4508005 tripartite motif-containing 26 [Homo sapiens]              241   9e-64
gi|117938316 tripartite motif-containing 22 [Homo sapiens]            236   3e-62
gi|51477687 tripartite motif protein 34 isoform 1 [Homo sapiens]      235   6e-62
gi|18087807 tripartite motif protein 34 isoform 1 [Homo sapiens]      235   6e-62
gi|51477690 tripartite motif-containing 6 and tripartite motif-c...   235   6e-62
gi|157426896 tripartite motif-containing 10 isoform 2 [Homo sapi...   229   6e-60

>gi|5730009 ret finger protein [Homo sapiens]
          Length = 513

 Score = 1070 bits (2766), Expect = 0.0
 Identities = 513/513 (100%), Positives = 513/513 (100%)

Query: 1   MASGSVAECLQQETTCPVCLQYFAEPMMLDCGHNICCACLARCWGTAETNVSCPQCRETF 60
           MASGSVAECLQQETTCPVCLQYFAEPMMLDCGHNICCACLARCWGTAETNVSCPQCRETF
Sbjct: 1   MASGSVAECLQQETTCPVCLQYFAEPMMLDCGHNICCACLARCWGTAETNVSCPQCRETF 60

Query: 61  PQRHMRPNRHLANVTQLVKQLRTERPSGPGGEMGVCEKHREPLKLYCEEDQMPICVVCDR 120
           PQRHMRPNRHLANVTQLVKQLRTERPSGPGGEMGVCEKHREPLKLYCEEDQMPICVVCDR
Sbjct: 61  PQRHMRPNRHLANVTQLVKQLRTERPSGPGGEMGVCEKHREPLKLYCEEDQMPICVVCDR 120

Query: 121 SREHRGHSVLPLEEAVEGFKEQIQNQLDHLKRVKDLKKRRRAQGEQARAELLSLTQMERE 180
           SREHRGHSVLPLEEAVEGFKEQIQNQLDHLKRVKDLKKRRRAQGEQARAELLSLTQMERE
Sbjct: 121 SREHRGHSVLPLEEAVEGFKEQIQNQLDHLKRVKDLKKRRRAQGEQARAELLSLTQMERE 180

Query: 181 KIVWEFEQLYHSLKEHEYRLLARLEELDLAIYNSINGAITQFSCNISHLSSLIAQLEEKQ 240
           KIVWEFEQLYHSLKEHEYRLLARLEELDLAIYNSINGAITQFSCNISHLSSLIAQLEEKQ
Sbjct: 181 KIVWEFEQLYHSLKEHEYRLLARLEELDLAIYNSINGAITQFSCNISHLSSLIAQLEEKQ 240

Query: 241 QQPTRELLQDIGDTLSRAERIRIPEPWITPPDLQEKIHIFAQKCLFLTESLKQFTEKMQS 300
           QQPTRELLQDIGDTLSRAERIRIPEPWITPPDLQEKIHIFAQKCLFLTESLKQFTEKMQS
Sbjct: 241 QQPTRELLQDIGDTLSRAERIRIPEPWITPPDLQEKIHIFAQKCLFLTESLKQFTEKMQS 300

Query: 301 DMEKIQELREAQLYSVDVTLDPDTAYPSLILSDNLRQVRYSYLQQDLPDNPERFNLFPCV 360
           DMEKIQELREAQLYSVDVTLDPDTAYPSLILSDNLRQVRYSYLQQDLPDNPERFNLFPCV
Sbjct: 301 DMEKIQELREAQLYSVDVTLDPDTAYPSLILSDNLRQVRYSYLQQDLPDNPERFNLFPCV 360

Query: 361 LGSPCFIAGRHYWEVEVGDKAKWTIGVCEDSVCRKGGVTSAPQNGFWAVSLWYGKEYWAL 420
           LGSPCFIAGRHYWEVEVGDKAKWTIGVCEDSVCRKGGVTSAPQNGFWAVSLWYGKEYWAL
Sbjct: 361 LGSPCFIAGRHYWEVEVGDKAKWTIGVCEDSVCRKGGVTSAPQNGFWAVSLWYGKEYWAL 420

Query: 421 TSPMTALPLRTPLQRVGIFLDYDAGEVSFYNVTERCHTFTFSHATFCGPVRPYFSLSYSG 480
           TSPMTALPLRTPLQRVGIFLDYDAGEVSFYNVTERCHTFTFSHATFCGPVRPYFSLSYSG
Sbjct: 421 TSPMTALPLRTPLQRVGIFLDYDAGEVSFYNVTERCHTFTFSHATFCGPVRPYFSLSYSG 480

Query: 481 GKSAAPLIICPMSGIDGFSGHVGNHGHSMETSP 513
           GKSAAPLIICPMSGIDGFSGHVGNHGHSMETSP
Sbjct: 481 GKSAAPLIICPMSGIDGFSGHVGNHGHSMETSP 513


>gi|25777698 tripartite motif-containing 39 isoform 2 [Homo sapiens]
          Length = 488

 Score =  362 bits (929), Expect = e-100
 Identities = 191/492 (38%), Positives = 288/492 (58%), Gaps = 25/492 (5%)

Query: 2   ASGSVAECLQQETTCPVCLQYFAEPMMLDCGHNICCACLARCWGTAETNVSCPQCRETFP 61
           ++ +  E LQ E +C VCL+Y  EP++++CGHN C AC+ R W   E +  CP CR+T  
Sbjct: 15  STAAALENLQVEASCSVCLEYLKEPVIIECGHNFCKACITRWWEDLERDFPCPVCRKTSR 74

Query: 62  QRHMRPNRHLANVTQLVKQLRTERPSGPGGEMGVCEKHREPLKLYCEEDQMPICVVCDRS 121
            R +RPNR L ++ ++ KQL+  +      +  +C +H E L L+C EDQ  +C++C  S
Sbjct: 75  YRSLRPNRQLGSMVEIAKQLQAVKRKIR--DESLCPQHHEALSLFCYEDQEAVCLICAIS 132

Query: 122 REHRGHSVLPLEEAVEGFKEQIQNQLDHLKRVKDLKKRRRAQGEQARAELLSLTQMEREK 181
             HR H+V+PL++A + +KE++Q  L+ L++      R ++  E+   EL  L +  R++
Sbjct: 133 HTHRAHTVVPLDDATQEYKEKLQKCLEPLEQKLQEITRCKSSEEKKPGELKRLVESRRQQ 192

Query: 182 IVWEFEQLYHSLKEHEYRLLARLEELDLAIYNSINGAITQFSCNISHLSSLIAQLEEKQQ 241
           I+ EFE+L+  L E +  LL+RLEE +  I   +             L+ L A++E K  
Sbjct: 193 ILREFEELHRRLDEEQQVLLSRLEEEEQDILQRLRENAAHLGDKRRDLAHLAAEVEGKCL 252

Query: 242 QPTRELLQDIGDTLSRAERIRIPEPWITPPDLQEKIHIFAQKCLFLTESLKQFTEKMQSD 301
           Q   E+L+D+  TL + E+++  E      +L++    F ++   L + LKQ        
Sbjct: 253 QSGFEMLKDVKSTLEKCEKVKTMEVTSVSIELEKNFSNFPRQYFALRKILKQLI------ 306

Query: 302 MEKIQELREAQLYSVDVTLDPDTAYPSLILSDNLRQVRYSYLQ-QDLPDNPERFNLFPCV 360
                          DVTLDP+TA+P+L+LS++ + V++   + +DLPD P RF  +PCV
Sbjct: 307 --------------ADVTLDPETAHPNLVLSEDRKSVKFVETRLRDLPDTPRRFTFYPCV 352

Query: 361 LGSPCFIAGRHYWEVEVGDKAKWTIGVCEDSVCRKGGVTSAPQNGFWAVSLWYGKEYWAL 420
           L +  F +GRHYWEVEVGDK  W +GVC DSV RKG +T  P+ G+W V LW G +Y A 
Sbjct: 353 LATEGFTSGRHYWEVEVGDKTHWAVGVCRDSVSRKGELTPLPETGYWRVRLWNGDKYAAT 412

Query: 421 TSPMTALPLRTPLQRVGIFLDYDAGEVSFYNVTERCHTFTFSHATFCGPVRPYFSLSY-S 479
           T+P T L ++   +RVGIFLDY+AG +SFYNVT+R H +TF+  TF   + P F     +
Sbjct: 413 TTPFTPLHIKVKPKRVGIFLDYEAGTLSFYNVTDRSHIYTFTD-TFTEKLWPLFYPGIRA 471

Query: 480 GGKSAAPLIICP 491
           G K+AAPL I P
Sbjct: 472 GRKNAAPLTIRP 483


>gi|21630277 tripartite motif-containing 11 [Homo sapiens]
          Length = 468

 Score =  361 bits (926), Expect = e-99
 Identities = 196/497 (39%), Positives = 278/497 (55%), Gaps = 35/497 (7%)

Query: 1   MASGSVAECLQQETTCPVCLQYFAEPMMLDCGHNICCACLARCWGTAETNVSCPQCRETF 60
           MA+  ++  LQ+E TC +CL YF +P+M DCGHN C  C+ RCWG  E   +CP+CRE  
Sbjct: 1   MAAPDLSTNLQEEATCAICLDYFTDPVMTDCGHNFCRECIRRCWGQPEGPYACPECRELS 60

Query: 61  PQRHMRPNRHLANVTQLVKQLRTERPSGPGGEMGVCEKHREPLKLYCEEDQMPICVVCDR 120
           PQR++RPNR LA + ++ ++L    P       GVC  HREPL  +C ++   +C  C+R
Sbjct: 61  PQRNLRPNRPLAKMAEMARRLHPPSPV----PQGVCPAHREPLAAFCGDELRLLCAACER 116

Query: 121 SREHRGHSVLPLEEAVEGFKEQIQNQLDHLKRVKDLKKRRRAQGEQARAELLSLTQMERE 180
           S EH  H V PL++A E  K +++  L+HL++        +AQ ++       + + +R+
Sbjct: 117 SGEHWAHRVRPLQDAAEDLKAKLEKSLEHLRKQMQDALLFQAQADETCVLWQKMVESQRQ 176

Query: 181 KIVWEFEQLYHSLKEHEYRLLARLEELDLAIYNSINGAITQFSCNISHLSSLIAQLEEKQ 240
            ++ EFE+L   L E E +LL RLEE +L +   +           +HL+ LIA+LE + 
Sbjct: 177 NVLGEFERLRRLLAEEEQQLLQRLEEEELEVLPRLREGAAHLGQQSAHLAELIAELEGRC 236

Query: 241 QQPTRELLQDIGDTLSRAERIRIPEPWITPPDLQEKIHIFAQKCLFLTESLKQFTEKMQS 300
           Q P   LLQDI D L R + +++  P + P +L+    +       L E+L++F      
Sbjct: 237 QLPALGLLQDIKDALRRVQDVKLQPPEVVPMELRTVCRVPG-----LVETLRRFRG---- 287

Query: 301 DMEKIQELREAQLYSVDVTLDPDTAYPSLILSDNLRQVRYSYLQQDLPDNPERFNLFPCV 360
                           DVTLDPDTA P LILS++ R V+   L+Q LPD+PERF+  PCV
Sbjct: 288 ----------------DVTLDPDTANPELILSEDRRSVQRGDLRQALPDSPERFDPGPCV 331

Query: 361 LGSPCFIAGRHYWEVEVGDKAKWTIGVCEDSVCRKGGVTSAPQNGFWAVSLWYGKEYWAL 420
           LG   F +GRHYWEVEVGD+  W +GVC ++V RK     +  NGFW + ++ G  Y   
Sbjct: 332 LGQERFTSGRHYWEVEVGDRTSWALGVCRENVNRKEKGELSAGNGFW-ILVFLGSYY--N 388

Query: 421 TSPMTALPLRTPLQRVGIFLDYDAGEVSFYNVTERCHTFTFSHATFCGPVRPYFSLSYSG 480
           +S     PLR P +RVGIFLDY+AG +SFY+ T+    F F    F G +RP FS   S 
Sbjct: 389 SSERALAPLRDPPRRVGIFLDYEAGHLSFYSATDGSLLFIFPEIPFSGTLRPLFSPLSS- 447

Query: 481 GKSAAPLIICPMSGIDG 497
             S  P+ IC   G  G
Sbjct: 448 --SPTPMTICRPKGGSG 462


>gi|4557743 Mediterranean fever protein [Homo sapiens]
          Length = 781

 Score =  350 bits (897), Expect = 2e-96
 Identities = 173/403 (42%), Positives = 265/403 (65%), Gaps = 4/403 (0%)

Query: 96  CEKHREPLKL-YCEEDQMPICVVCDRSREHRGHSVLPLEEAVEGFKEQIQNQLDHLKRVK 154
           C++H + ++L +CE+   PIC++C  S+EH+GH V P+EE     K++IQ QL+HLK+++
Sbjct: 375 CKRHLKQVQLLFCEDHDEPICLICSLSQEHQGHRVRPIEEVALEHKKKIQKQLEHLKKLR 434

Query: 155 DLKKRRRAQGEQARAELLSLTQMEREKIVWEFEQLYHSLKEHEYRLLARLEELDLAIYNS 214
              + +R+ GE+     L  T+  ++++  + EQ+Y+ L++ E+  +A LE++   +   
Sbjct: 435 KSGEEQRSYGEEKAVSFLKQTEALKQRVQRKLEQVYYFLEQQEHFFVASLEDVGQMVGQI 494

Query: 215 INGAITQFSCNISHLSSLIAQLEEKQQQPTRELLQDIGDTLSRAERIRIPEPWITPPDLQ 274
                T+ S +I+ L +LI +LE K+ Q   ELLQDIGD L RA+ + +PE W TP +++
Sbjct: 495 RKAYDTRVSQDIALLDALIGELEAKECQSEWELLQDIGDILHRAKTVPVPEKWTTPQEIK 554

Query: 275 EKIHIFAQKCLFLTESLKQFTEKMQSDME--KIQELREAQLYSVDVTLDPDTAYPSLILS 332
           +KI +  QK  F+ +S K F+E ++S+ME   + EL  AQ ++V+V LD +TAYP+LI S
Sbjct: 555 QKIQLLHQKSEFVEKSTKYFSETLRSEMEMFNVPELIGAQAHAVNVILDAETAYPNLIFS 614

Query: 333 DNLRQVRYSYLQQDLPDNPERFNLFPCVLGSPCFIAGRHYWEVEVGDKAKWTIGVCEDSV 392
           D+L+ VR     + LPD P+RF+    VLGSP F++GR YWEVEVGDK  W +G C+ S+
Sbjct: 615 DDLKSVRLGNKWERLPDGPQRFDSCIIVLGSPSFLSGRRYWEVEVGDKTAWILGACKTSI 674

Query: 393 CRKGGVTSAPQNGFWAVSLWYGKEYWALTSPMTALPLRTPLQRVGIFLDYDAGEVSFYNV 452
            RKG +T +P+NG+W V +    EY A + P T L ++ P +RVGIF+DY  G +SFYNV
Sbjct: 675 SRKGNMTLSPENGYWVVIMMKENEYQASSVPPTRLLIKEPPKRVGIFVDYRVGSISFYNV 734

Query: 453 TERCHTFTFSHATFCGPVRPYFSL-SYSGGKSAAPLIICPMSG 494
           T R H +TF+  +F GP++P FS  +  GGK+ APL ICP+ G
Sbjct: 735 TARSHIYTFASCSFSGPLQPIFSPGTRDGGKNTAPLTICPVGG 777


>gi|25777696 tripartite motif-containing 39 isoform 1 [Homo sapiens]
          Length = 518

 Score =  348 bits (894), Expect = 5e-96
 Identities = 192/506 (37%), Positives = 293/506 (57%), Gaps = 23/506 (4%)

Query: 2   ASGSVAECLQQETTCPVCLQYFAEPMMLDCGHNICCACLARCWGTAETNVSCPQCRETFP 61
           ++ +  E LQ E +C VCL+Y  EP++++CGHN C AC+ R W   E +  CP CR+T  
Sbjct: 15  STAAALENLQVEASCSVCLEYLKEPVIIECGHNFCKACITRWWEDLERDFPCPVCRKTSR 74

Query: 62  QRHMRPNRHLANVTQLVKQLRTERPSGPGGEMGVCEKHREPLKLYCEEDQMPICVVCDRS 121
            R +RPNR L ++ ++ KQL+  +      +  +C +H E L L+C EDQ  +C++C  S
Sbjct: 75  YRSLRPNRQLGSMVEIAKQLQAVKRKIR--DESLCPQHHEALSLFCYEDQEAVCLICAIS 132

Query: 122 REHRGHSVLPLEEAVEGFKEQIQNQLDHLKRVKDLKKRRRAQGEQARAELLSLTQMEREK 181
             HR H+V+PL++A + +KE++Q  L+ L++      R ++  E+   EL  L +  R++
Sbjct: 133 HTHRAHTVVPLDDATQEYKEKLQKCLEPLEQKLQEITRCKSSEEKKPGELKRLVESRRQQ 192

Query: 182 IVWEFEQLYHSLKEHEYRLLARLEELDLAIYNSINGAITQFSCNISHLSSLIAQLEEKQQ 241
           I+ EFE+L+  L E +  LL+RLEE +  I   +             L+ L A++E K  
Sbjct: 193 ILREFEELHRRLDEEQQVLLSRLEEEEQDILQRLRENAAHLGDKRRDLAHLAAEVEGKCL 252

Query: 242 QPTRELLQDIGDTLSRAERIRIPEPW------ITPPDLQEKIHIFAQ-------KCLFLT 288
           Q   E+L+D+  TL +     IP  +      I P D +  + +  +       K + +T
Sbjct: 253 QSGFEMLKDVKSTLEK----NIPRKFGGSLSTICPRDHKALLGLVKEINRCEKVKTMEVT 308

Query: 289 ESLKQFTEKMQSDMEKIQELREAQLYSV-DVTLDPDTAYPSLILSDNLRQVRYSYLQ-QD 346
               +  +   +   +   LR+     + DVTLDP+TA+P+L+LS++ + V++   + +D
Sbjct: 309 SVSIELEKNFSNFPRQYFALRKILKQLIADVTLDPETAHPNLVLSEDRKSVKFVETRLRD 368

Query: 347 LPDNPERFNLFPCVLGSPCFIAGRHYWEVEVGDKAKWTIGVCEDSVCRKGGVTSAPQNGF 406
           LPD P RF  +PCVL +  F +GRHYWEVEVGDK  W +GVC DSV RKG +T  P+ G+
Sbjct: 369 LPDTPRRFTFYPCVLATEGFTSGRHYWEVEVGDKTHWAVGVCRDSVSRKGELTPLPETGY 428

Query: 407 WAVSLWYGKEYWALTSPMTALPLRTPLQRVGIFLDYDAGEVSFYNVTERCHTFTFSHATF 466
           W V LW G +Y A T+P T L ++   +RVGIFLDY+AG +SFYNVT+R H +TF+  TF
Sbjct: 429 WRVRLWNGDKYAATTTPFTPLHIKVKPKRVGIFLDYEAGTLSFYNVTDRSHIYTFTD-TF 487

Query: 467 CGPVRPYFSLSY-SGGKSAAPLIICP 491
              + P F     +G K+AAPL I P
Sbjct: 488 TEKLWPLFYPGIRAGRKNAAPLTIRP 513


>gi|15208660 tripartite motif protein 21 [Homo sapiens]
          Length = 475

 Score =  332 bits (851), Expect = 5e-91
 Identities = 186/495 (37%), Positives = 282/495 (56%), Gaps = 31/495 (6%)

Query: 1   MASGSVAECLQQETTCPVCLQYFAEPMMLDCGHNICCACLARCWGTAETNVSCPQCRETF 60
           MAS +    + +E TCP+CL  F EP+ ++CGH+ C  C+++  G    +V CP CR+ F
Sbjct: 1   MASAARLTMMWEEVTCPICLDPFVEPVSIECGHSFCQECISQV-GKGGGSV-CPVCRQRF 58

Query: 61  PQRHMRPNRHLANVTQLVKQLRTERPSGPGGEMGVCEKHREPLKLYCEEDQMPICVVCDR 120
             +++RPNR LAN+   +K++  E   G  GE   C  H E L L+CE+D   +C VC +
Sbjct: 59  LLKNLRPNRQLANMVNNLKEISQEAREGTQGER--CAVHGERLHLFCEKDGKALCWVCAQ 116

Query: 121 SREHRGHSVLPLEEAVEGFKEQIQNQLDHLKRVKDLKKRRRAQGEQARAELLSLTQMERE 180
           SR+HR H+++PLEEA + ++E++Q  L  L+R ++L ++   +    RA+     + ++ 
Sbjct: 117 SRKHRDHAMVPLEEAAQEYQEKLQVALGELRRKQELAEKLEVEIAIKRADWKKTVETQKS 176

Query: 181 KIVWEFEQLYHSLKEHEYRLLARLEELDLAIYNSINGAITQFSCNISHLSSLIAQLEEKQ 240
           +I  EF Q  + L E E R L  LE+ +      +     + +     L  LI++L+ + 
Sbjct: 177 RIHAEFVQQKNFLVEEEQRQLQELEKDEREQLRILGEKEAKLAQQSQALQELISELDRRC 236

Query: 241 QQPTRELLQDIGDTLSRAERIRIPEPWITPPDLQEKIHIFAQKCLFLTESLKQFTEKMQS 300
                ELLQ++   L R+E   + +  IT P+L+   H+   K +  T            
Sbjct: 237 HSSALELLQEVIIVLERSESWNLKDLDITSPELRSVCHVPGLKKMLRT------------ 284

Query: 301 DMEKIQELREAQLYSVDVTLDPDTAYPSLILSDNLRQVRYSYLQQDLPDNPERFNLFPCV 360
                         +V +TLDPDTA P LILS++ RQVR    QQ +P N ERF+ +P V
Sbjct: 285 -------------CAVHITLDPDTANPWLILSEDRRQVRLGDTQQSIPGNEERFDSYPMV 331

Query: 361 LGSPCFIAGRHYWEVEVGDKAKWTIGVCEDSVCRKGGVTSAPQNGFWAVSLWYGKEYWAL 420
           LG+  F +G+HYWEV+V  K  W +GVC DSV RKG    + ++GFW + LW  ++Y A 
Sbjct: 332 LGAQHFHSGKHYWEVDVTGKEAWDLGVCRDSVRRKGHFLLSSKSGFWTIWLWNKQKYEAG 391

Query: 421 TSPMTALPLRTPLQRVGIFLDYDAGEVSFYNVTER-CHTFTFSHATFCGPVRPYFSLSYS 479
           T P T L L+ P  +VGIFLDY+AG VSFYN+T+     ++FS   F GP+RP+FS  ++
Sbjct: 392 TYPQTPLHLQVPPCQVGIFLDYEAGMVSFYNITDHGSLIYSFSECAFTGPLRPFFSPGFN 451

Query: 480 -GGKSAAPLIICPMS 493
            GGK+ APL +CP++
Sbjct: 452 DGGKNTAPLTLCPLN 466


>gi|44680122 tripartite motif-containing 7 isoform 1 [Homo sapiens]
          Length = 511

 Score =  330 bits (847), Expect = 1e-90
 Identities = 199/500 (39%), Positives = 280/500 (56%), Gaps = 37/500 (7%)

Query: 5   SVAECLQQETTCPVCLQYFAEPMMLDCGHNICCACLARCW---GTAETNVS--------- 52
           ++A  LQ E TC +CL+ F EP+ ++CGH+ C AC+ RCW   G      +         
Sbjct: 18  ALAAELQGEATCSICLELFREPVSVECGHSFCRACIGRCWERPGAGSVGAATRAPPFPLP 77

Query: 53  CPQCRETFPQRHMRPNRHLANVTQLVKQLRTERPSGPGGEMGV-----------CEKHRE 101
           CPQCRE      +RPNR LA V  L++  R   P+   GE G            C +H E
Sbjct: 78  CPQCREPARPSQLRPNRQLAAVATLLR--RFSLPAAAPGEHGSQAAAARAAAARCGQHGE 135

Query: 102 PLKLYCEEDQMPICVVCDRSREHRGHSVLPLEEAVEGFKEQIQNQLDHLKR-VKDLKKRR 160
           P KLYC++D   ICVVCDR+REHR H+VLPL+EAV+  KE ++++L  LK+ ++D +  R
Sbjct: 136 PFKLYCQDDGRAICVVCDRAREHREHAVLPLDEAVQEAKELLESRLRVLKKELEDCEVFR 195

Query: 161 RAQGEQARAELLSLTQMEREKIVWEFEQLYHSLKEHEYRLLARLEELDLAIYNSINGAIT 220
             + ++++ ELL     E+EK+  EF+ L   L E E RLL RLEEL   +    N  + 
Sbjct: 196 STEKKESK-ELLKQMAAEQEKVGAEFQALRAFLVEQEGRLLGRLEELSREVAQKQNENLA 254

Query: 221 QFSCNISHLSSLIAQLEEKQQQPTRELLQDIGDTLSRAERIRIPEPWITPPDLQEKIHIF 280
           Q    I+ LS L +Q++E  Q+P  + LQ+   TLSR   +  P+P     +++ K+   
Sbjct: 255 QLGVEITQLSKLSSQIQETAQKPDLDFLQEFKSTLSRCSNVPGPKPTTVSSEMKNKVWNV 314

Query: 281 AQKCLFLTESLKQFTEKMQSDMEKIQELREAQLYSVDVTLDPDTAYPSLILSDNLRQVRY 340
           + K   L   LK+F E ++ ++EK ++        V++TLDPDTA P LILS +L+ VR 
Sbjct: 315 SLKTFVLKGMLKKFKEDLRGELEKEEK--------VELTLDPDTANPRLILSLDLKGVRL 366

Query: 341 SYLQQDLPDNPERFNLFPCVLGSPCFIAGRHYWEVEVGDKAKWTIGVCEDSVCRKGGVTS 400
               QDLP++P RF+    VL S  F +GRH+WEVEVG K  W  GV  +SV RKG    
Sbjct: 367 GERAQDLPNHPCRFDTNTRVLASCGFSSGRHHWEVEVGSKDGWAFGVARESVRRKGLTPF 426

Query: 401 APQNGFWAVSLWYGKEYWALTSPMTALPLRTPLQRVGIFLDYDAGEVSFYNVTERCHTFT 460
            P+ G WA+ L  G +YWA+TSP  +      L RV + LD + G VSFY V +  H +T
Sbjct: 427 TPEEGVWALQL-NGGQYWAVTSPERSPLSCGHLSRVRVALDLEVGAVSFYAVEDMRHLYT 485

Query: 461 FSHATFCGPVRPYFSLSYSG 480
           F    F   V P FS+  +G
Sbjct: 486 F-RVNFQERVFPLFSVCSTG 504


>gi|37622899 ring finger protein 137 [Homo sapiens]
          Length = 485

 Score =  327 bits (837), Expect = 2e-89
 Identities = 194/510 (38%), Positives = 282/510 (55%), Gaps = 47/510 (9%)

Query: 5   SVAECLQQETTCPVCLQYFAEPMMLDCGHNICCACLARCW---GTAET-NVSCPQCRETF 60
           ++ E + +E  CP+C+ +  EPM +DCGH+ C +CL+  W   G ++    +CP CR   
Sbjct: 5   ALVEAIVEEVACPICMTFLREPMSIDCGHSFCHSCLSGLWEIPGESQNWGYTCPLCRAPV 64

Query: 61  PQRHMRPNRHLANVTQLVKQLRTERPSGPGGEMGVCEKHREPLKLYCEEDQMPICVVCDR 120
             R++RPN  LANV + V+ LR     G  G++  CE+H E LK++C+ED + +C  C +
Sbjct: 65  QPRNLRPNWQLANVVEKVRLLRLHPGMGLKGDL--CERHGEKLKMFCKEDVLIMCEACSQ 122

Query: 121 SREHRGHSVLPLEEAVEGFKEQIQNQLDHLKRVKDLKKRRRAQGEQARAELLSL-TQMER 179
           S EH  HSV+P+E+    +K ++   L+HLK+ ++ +  +   GE+ R     +  +  +
Sbjct: 123 SPEHEAHSVVPMEDVAWEYKWELHEALEHLKKEQE-EAWKLEVGERKRTATWKIQVETRK 181

Query: 180 EKIVWEFEQLYHSL--KEHEYRLLARLEELDLAIYNSINGAITQFSCNISH--------- 228
           + IVWEFE+    L  K+  +R L       LA       A T     ++H         
Sbjct: 182 QSIVWEFEKYQRLLEKKQPPHRQLGAEVAAALASLQR-EAAETMQKLELNHSELIQQSQV 240

Query: 229 LSSLIAQLEEKQQQPTRELLQDIGDTLSRAERIRIPEPWITPPDLQEKIHIFAQKCLFLT 288
           L  +IA+L+E+ Q+P R +LQDI + L+R++   + +P   P  L+ K      + L L 
Sbjct: 241 LWRMIAELKERSQRPVRWMLQDIQEVLNRSKSWSLQQP--EPISLELKTDC---RVLGLR 295

Query: 289 ESLKQFTEKMQSDMEKIQELREAQLYSVDVTLDPDTAYPSLILSDNLRQVRYSYLQQDLP 348
           E LK                     Y+ DV LDPDTAY  LI+S++ ++V Y    Q LP
Sbjct: 296 EILKT--------------------YAADVRLDPDTAYSRLIVSEDRKRVHYGDTNQKLP 335

Query: 349 DNPERFNLFPCVLGSPCFIAGRHYWEVEVGDKAKWTIGVCEDSVCRKGGVTSAPQNGFWA 408
           DNPERF  +  VLGS C  +GRHYWEVEVGD+++W +GVC+ +V RK  V  +P  GFW 
Sbjct: 336 DNPERFYRYNIVLGSQCISSGRHYWEVEVGDRSEWGLGVCKQNVDRKEVVYLSPHYGFWV 395

Query: 409 VSLWYGKEYWALTSPMTALPLRTPLQRVGIFLDYDAGEVSFYNVTE-RCHTFTFSHATFC 467
           + L  G EY A T     L L  P +RVGIF+DY+A ++SFYNVT+   H FTF    F 
Sbjct: 396 IRLRKGNEYRAGTDEYPILSLPVPPRRVGIFVDYEAHDISFYNVTDCGSHIFTFPRYPFP 455

Query: 468 GPVRPYFSLSYS-GGKSAAPLIICPMSGID 496
           G + PYFS  YS G  + APL IC + G D
Sbjct: 456 GRLLPYFSPCYSIGTNNTAPLAICSLDGED 485


>gi|68160933 tripartite motif-containing 17 isoform 1 [Homo sapiens]
          Length = 477

 Score =  315 bits (807), Expect = 6e-86
 Identities = 184/496 (37%), Positives = 268/496 (54%), Gaps = 58/496 (11%)

Query: 1   MASGSVAECLQQETTCPVCLQYFAEPMMLDCGHNICCACLARCWGTA---------ETNV 51
           M +  +A  LQ+E TC +CL YF +P+M  CGHN C AC+   W  A         + + 
Sbjct: 1   MEAVELARKLQEEATCSICLDYFTDPVMTTCGHNFCRACIQLSWEKARGKKGRRKRKGSF 60

Query: 52  SCPQCRETFPQRHMRPNRHLANVTQLVKQLRTERPSGPG-GEMGVCEKHREPLKLYCEED 110
            CP+CRE  PQR++ PNR L  V ++ +Q        PG  +  +C++H EPLKL+C++D
Sbjct: 61  PCPECREMSPQRNLLPNRLLTKVAEMAQQ-------HPGLQKQDLCQEHHEPLKLFCQKD 113

Query: 111 QMPICVVCDRSREHRGHSVLPLEEAVEGFKEQIQNQLDHLKRVKDLKKRRRAQGEQARAE 170
           Q PICVVC  SREHR H VLP EEAV+G+K +++  +++L+         +A+ EQ+ AE
Sbjct: 114 QSPICVVCRESREHRLHRVLPAEEAVQGYKLKLEEDMEYLREQITRTGNLQAREEQSLAE 173

Query: 171 LLSLTQMEREKIVWEFEQLYHSLKEHEYRLLARLEELDLAIYNSINGAITQFSCNISHLS 230
                +  RE+IV EFE++   L E E RLL  LE  +    + +  ++         L 
Sbjct: 174 WQGKVKERRERIVLEFEKMNLYLVEEEQRLLQALETEEEETASRLRESVACLDRQGHSLE 233

Query: 231 SLIAQLEEKQQQPTRELLQDIGDTLSRAERIRIPEPWITPPDLQEKIHIFAQKCLFLTES 290
            L+ QLEE+  Q   ++LQD+ + LSR   + +  P + PP     +      C      
Sbjct: 234 LLLLQLEERSTQGPLQMLQDMKEPLSRKNNVSVQCPEVAPPTRPRTV------C------ 281

Query: 291 LKQFTEKMQSDMEKIQELREAQLYSVDVTLDPDTAYPSLILSDNLRQVRYSYLQQDLPDN 350
                 ++   +E ++   E      DV  D  +AYP L+L ++ RQ RY      L  +
Sbjct: 282 ------RVPGQIEVLRGFLE------DVVPDATSAYPYLLLYES-RQRRY------LGSS 322

Query: 351 PE--------RFNLFPCVLGSPCFIAGRHYWEV--EVGDKAKWTIGVCEDSVCRKGGVTS 400
           PE        RF  +PC +G   F +GRHYWEV   +   A W +GVC D+V RK  V  
Sbjct: 323 PEGSGFCSKDRFVAYPCAVGQTAFSSGRHYWEVGMNITGDALWALGVCRDNVSRKDRVPK 382

Query: 401 APQNGFWAVSLWYGKEYWALTSPMTALPLRTPLQRVGIFLDYDAGEVSFYNVTERCHTFT 460
            P+NGFW V L  G +Y +  S +T + L  P   +GIFLD++AGEVSFY+V++  H  T
Sbjct: 383 CPENGFWVVQLSKGTKYLSTFSALTPVMLMEPPSHMGIFLDFEAGEVSFYSVSDGSHLHT 442

Query: 461 FSHATFCGPVRPYFSL 476
           +S ATF GP++P+F L
Sbjct: 443 YSQATFPGPLQPFFCL 458


>gi|7705825 tripartite motif-containing 17 isoform 1 [Homo sapiens]
          Length = 477

 Score =  315 bits (807), Expect = 6e-86
 Identities = 184/496 (37%), Positives = 268/496 (54%), Gaps = 58/496 (11%)

Query: 1   MASGSVAECLQQETTCPVCLQYFAEPMMLDCGHNICCACLARCWGTA---------ETNV 51
           M +  +A  LQ+E TC +CL YF +P+M  CGHN C AC+   W  A         + + 
Sbjct: 1   MEAVELARKLQEEATCSICLDYFTDPVMTTCGHNFCRACIQLSWEKARGKKGRRKRKGSF 60

Query: 52  SCPQCRETFPQRHMRPNRHLANVTQLVKQLRTERPSGPG-GEMGVCEKHREPLKLYCEED 110
            CP+CRE  PQR++ PNR L  V ++ +Q        PG  +  +C++H EPLKL+C++D
Sbjct: 61  PCPECREMSPQRNLLPNRLLTKVAEMAQQ-------HPGLQKQDLCQEHHEPLKLFCQKD 113

Query: 111 QMPICVVCDRSREHRGHSVLPLEEAVEGFKEQIQNQLDHLKRVKDLKKRRRAQGEQARAE 170
           Q PICVVC  SREHR H VLP EEAV+G+K +++  +++L+         +A+ EQ+ AE
Sbjct: 114 QSPICVVCRESREHRLHRVLPAEEAVQGYKLKLEEDMEYLREQITRTGNLQAREEQSLAE 173

Query: 171 LLSLTQMEREKIVWEFEQLYHSLKEHEYRLLARLEELDLAIYNSINGAITQFSCNISHLS 230
                +  RE+IV EFE++   L E E RLL  LE  +    + +  ++         L 
Sbjct: 174 WQGKVKERRERIVLEFEKMNLYLVEEEQRLLQALETEEEETASRLRESVACLDRQGHSLE 233

Query: 231 SLIAQLEEKQQQPTRELLQDIGDTLSRAERIRIPEPWITPPDLQEKIHIFAQKCLFLTES 290
            L+ QLEE+  Q   ++LQD+ + LSR   + +  P + PP     +      C      
Sbjct: 234 LLLLQLEERSTQGPLQMLQDMKEPLSRKNNVSVQCPEVAPPTRPRTV------C------ 281

Query: 291 LKQFTEKMQSDMEKIQELREAQLYSVDVTLDPDTAYPSLILSDNLRQVRYSYLQQDLPDN 350
                 ++   +E ++   E      DV  D  +AYP L+L ++ RQ RY      L  +
Sbjct: 282 ------RVPGQIEVLRGFLE------DVVPDATSAYPYLLLYES-RQRRY------LGSS 322

Query: 351 PE--------RFNLFPCVLGSPCFIAGRHYWEV--EVGDKAKWTIGVCEDSVCRKGGVTS 400
           PE        RF  +PC +G   F +GRHYWEV   +   A W +GVC D+V RK  V  
Sbjct: 323 PEGSGFCSKDRFVAYPCAVGQTAFSSGRHYWEVGMNITGDALWALGVCRDNVSRKDRVPK 382

Query: 401 APQNGFWAVSLWYGKEYWALTSPMTALPLRTPLQRVGIFLDYDAGEVSFYNVTERCHTFT 460
            P+NGFW V L  G +Y +  S +T + L  P   +GIFLD++AGEVSFY+V++  H  T
Sbjct: 383 CPENGFWVVQLSKGTKYLSTFSALTPVMLMEPPSHMGIFLDFEAGEVSFYSVSDGSHLHT 442

Query: 461 FSHATFCGPVRPYFSL 476
           +S ATF GP++P+F L
Sbjct: 443 YSQATFPGPLQPFFCL 458


>gi|112421127 tripartite motif-containing 58 [Homo sapiens]
          Length = 486

 Score =  298 bits (762), Expect = 1e-80
 Identities = 176/495 (35%), Positives = 266/495 (53%), Gaps = 39/495 (7%)

Query: 1   MASGSVAECLQQETTCPVCLQYFAEPMMLDCGHNICCACLA----RCWGTAETNVSCPQC 56
           MA     E L+++  CPVCL +  EP+ +DCGH+ C  C++    +  G      +CPQC
Sbjct: 1   MAWAPPGERLREDARCPVCLDFLQEPVSVDCGHSFCLRCISEFCEKSDGAQGGVYACPQC 60

Query: 57  RETFPQRHMRPNRHLANVTQLVKQLRTERPSGPGGEMGVCEKHREPLKLYCEEDQMPICV 116
           R  F     RPNR LA + + V++L     +GPG     C +H E L  +CEED+  +C 
Sbjct: 61  RGPFRPSGFRPNRQLAGLVESVRRLGLG--AGPGARR--CARHGEDLSRFCEEDEAALCW 116

Query: 117 VCDRSREHRGHSVLPLEEAVEGFKEQIQNQLDHLKRVKDLKKRRRAQGEQARAELLSLTQ 176
           VCD   EHR H   PL+EA   ++ ++Q  L+ +++  +    + A   +         +
Sbjct: 117 VCDAGPEHRTHRTAPLQEAAGSYQVKLQMALELMRKELEDALTQEANVGKKTVIWKEKVE 176

Query: 177 MEREKIVWEFEQLYHSLKEHEYRLLARLEELDLAIYNSINGAITQFSCNISHLSSLIAQL 236
           M+R++   EFE+    L + E R L RLE  + A    +  + ++       L  L  +L
Sbjct: 177 MQRQRFRLEFEKHRGFLAQEEQRQLRRLEAEERATLQRLRESKSRLVQQSKALKELADEL 236

Query: 237 EEKQQQPTRELLQDIGDTLSRAERIRIPEPWITPPDLQEKIHIFAQKCLFLTESLKQFTE 296
           +E+ Q+P   LL+ +   LSR++ +   E    P +L+    I  ++     E L++F  
Sbjct: 237 QERCQRPALGLLEGVRGVLSRSKAVTRLEAENIPMELKTACCIPGRR-----ELLRKF-- 289

Query: 297 KMQSDMEKIQELREAQLYSVDVTLDPDTAYPSLILSDNLRQVRYSYLQQDLPDNPERFNL 356
                              VDV LDP TA+PSL+L+ +LR V+     +D+P+NPERF+ 
Sbjct: 290 ------------------QVDVKLDPATAHPSLLLTADLRSVQDGEPWRDVPNNPERFDT 331

Query: 357 FPCVLGSPCFIAGRHYWEVEVGDKAKWTIGVCEDSVCRKGGVTSAPQNGFWAVSLWYGKE 416
           +PC+LG   F +GRHYWEV VG+ A+W +GVC+D++ RKG  T +P+NG WA+ L  G E
Sbjct: 332 WPCILGLQSFSSGRHYWEVLVGEGAEWGLGVCQDTLPRKGETTPSPENGVWALWLLKGNE 391

Query: 417 YWALTSPMTALPLRTPLQRVGIFLDYDAGEVSFYNVTERCHTFTFSHATFCGPVRPYFSL 476
           Y  L SP   L      + +GIFLDY+AGE+SFYNVT+  + +TF+   F G +RPYF +
Sbjct: 392 YMVLASPSVPLLQLESPRCIGIFLDYEAGEISFYNVTDGSYIYTFNQ-LFSGLLRPYFFI 450

Query: 477 SYSGGKSAAPLIICP 491
                  A PLI+ P
Sbjct: 451 C-----DATPLILPP 460


>gi|68160935 tripartite motif-containing 17 isoform 2 [Homo sapiens]
          Length = 450

 Score =  287 bits (735), Expect = 1e-77
 Identities = 172/469 (36%), Positives = 250/469 (53%), Gaps = 58/469 (12%)

Query: 28  MLDCGHNICCACLARCWGTA---------ETNVSCPQCRETFPQRHMRPNRHLANVTQLV 78
           M  CGHN C AC+   W  A         + +  CP+CRE  PQR++ PNR L  V ++ 
Sbjct: 1   MTTCGHNFCRACIQLSWEKARGKKGRRKRKGSFPCPECREMSPQRNLLPNRLLTKVAEMA 60

Query: 79  KQLRTERPSGPG-GEMGVCEKHREPLKLYCEEDQMPICVVCDRSREHRGHSVLPLEEAVE 137
           +Q        PG  +  +C++H EPLKL+C++DQ PICVVC  SREHR H VLP EEAV+
Sbjct: 61  QQ-------HPGLQKQDLCQEHHEPLKLFCQKDQSPICVVCRESREHRLHRVLPAEEAVQ 113

Query: 138 GFKEQIQNQLDHLKRVKDLKKRRRAQGEQARAELLSLTQMEREKIVWEFEQLYHSLKEHE 197
           G+K +++  +++L+         +A+ EQ+ AE     +  RE+IV EFE++   L E E
Sbjct: 114 GYKLKLEEDMEYLREQITRTGNLQAREEQSLAEWQGKVKERRERIVLEFEKMNLYLVEEE 173

Query: 198 YRLLARLEELDLAIYNSINGAITQFSCNISHLSSLIAQLEEKQQQPTRELLQDIGDTLSR 257
            RLL  LE  +    + +  ++         L  L+ QLEE+  Q   ++LQD+ + LSR
Sbjct: 174 QRLLQALETEEEETASRLRESVACLDRQGHSLELLLLQLEERSTQGPLQMLQDMKEPLSR 233

Query: 258 AERIRIPEPWITPPDLQEKIHIFAQKCLFLTESLKQFTEKMQSDMEKIQELREAQLYSVD 317
              + +  P + PP     +      C            ++   +E ++   E      D
Sbjct: 234 KNNVSVQCPEVAPPTRPRTV------C------------RVPGQIEVLRGFLE------D 269

Query: 318 VTLDPDTAYPSLILSDNLRQVRYSYLQQDLPDNPE--------RFNLFPCVLGSPCFIAG 369
           V  D  +AYP L+L ++ RQ RY      L  +PE        RF  +PC +G   F +G
Sbjct: 270 VVPDATSAYPYLLLYES-RQRRY------LGSSPEGSGFCSKDRFVAYPCAVGQTAFSSG 322

Query: 370 RHYWEV--EVGDKAKWTIGVCEDSVCRKGGVTSAPQNGFWAVSLWYGKEYWALTSPMTAL 427
           RHYWEV   +   A W +GVC D+V RK  V   P+NGFW V L  G +Y +  S +T +
Sbjct: 323 RHYWEVGMNITGDALWALGVCRDNVSRKDRVPKCPENGFWVVQLSKGTKYLSTFSALTPV 382

Query: 428 PLRTPLQRVGIFLDYDAGEVSFYNVTERCHTFTFSHATFCGPVRPYFSL 476
            L  P   +GIFLD++AGEVSFY+V++  H  T+S ATF GP++P+F L
Sbjct: 383 MLMEPPSHMGIFLDFEAGEVSFYSVSDGSHLHTYSQATFPGPLQPFFCL 431


>gi|5454014 tripartite motif-containing 38 [Homo sapiens]
          Length = 465

 Score =  287 bits (735), Expect = 1e-77
 Identities = 167/482 (34%), Positives = 255/482 (52%), Gaps = 36/482 (7%)

Query: 1   MASGSVAECLQQETTCPVCLQYFAEPMMLDCGHNICCACLARCWGTA------ETNVSCP 54
           MAS +  + + +E TC +CL     P+ ++CGH+ C  C+   +         +    CP
Sbjct: 1   MASTTSTKKMMEEATCSICLSLMTNPVSINCGHSYCHLCITDFFKNPSQKQLRQETFCCP 60

Query: 55  QCRETFPQRHMRPNRHLANVTQLVKQLRTERPSGPGGEMGVCEKHREPLKLYCEEDQMPI 114
           QCR  F    +RPN+ L ++ + +K+   E           CE+H E   L+CE++   I
Sbjct: 61  QCRAPFHMDSLRPNKQLGSLIEALKETDQEMS---------CEEHGEQFHLFCEDEGQLI 111

Query: 115 CVVCDRSREHRGHSVLPLEEAVEGFKEQIQNQLDHLKRVKDLKKRRRAQGEQARAELLSL 174
           C  C+R+ +H+GH+   +E+  +G+KE++Q  +  LK+++D    ++        +    
Sbjct: 112 CWRCERAPQHKGHTTALVEDVCQGYKEKLQKAVTKLKQLEDRCTEQKLSTAMRITKWKEK 171

Query: 175 TQMEREKIVWEFEQLYHSLKEHEYRLLARLEELDLAIYNSINGAITQFSCNISHLSSLIA 234
            Q++R+KI  +F+ L   L E E   L RLE+ +    + +           + L S I 
Sbjct: 172 VQIQRQKIRSDFKNLQCFLHEEEKSYLWRLEKEEQQTLSRLRDYEAGLGLKSNELKSHIL 231

Query: 235 QLEEKQQQPTRELLQDIGDTLSRAERIRIPEPWITPPDLQEKIHIFAQKCLFLTESLKQF 294
           +LEEK Q   ++LLQ++ DTLSR+  +++     T   +  ++H                
Sbjct: 232 ELEEKCQGSAQKLLQNVNDTLSRSWAVKLE----TSEAVSLELHTMCN------------ 275

Query: 295 TEKMQSDMEKIQELREAQLYSVDVTLDPDTAYPSLILSDNLRQVRYSYLQQDLPDNPERF 354
             K+  D++K+  LR  Q   V VTLDPDTA+  LILS++ RQV   Y Q++   +  RF
Sbjct: 276 VSKLYFDVKKM--LRSHQ---VSVTLDPDTAHHELILSEDRRQVTRGYTQENQDTSSRRF 330

Query: 355 NLFPCVLGSPCFIAGRHYWEVEVGDKAKWTIGVCEDSVCRKGGVTSAPQNGFWAVSLWYG 414
             FPCVLG   F +GR Y+EV+VG+   W +GVC ++V R  G+   PQ+GFW + L   
Sbjct: 331 TAFPCVLGCEGFTSGRRYFEVDVGEGTGWDLGVCMENVQRGTGMKQEPQSGFWTLRLCKK 390

Query: 415 KEYWALTSPMTALPLRTPLQRVGIFLDYDAGEVSFYNVTERCHTFTFSHATFCGPVRPYF 474
           K Y ALTSP T+L L      VGIFLDY+AG VSFYN    CH FTF  A+F   +RPYF
Sbjct: 391 KGYVALTSPPTSLHLHEQPLLVGIFLDYEAGVVSFYNGNTGCHIFTFPKASFSDTLRPYF 450

Query: 475 SL 476
            +
Sbjct: 451 QV 452


>gi|157743261 tripartite motif-containing 75 [Homo sapiens]
          Length = 468

 Score =  279 bits (714), Expect = 4e-75
 Identities = 163/492 (33%), Positives = 267/492 (54%), Gaps = 32/492 (6%)

Query: 1   MASGSVAECLQQETTCPVCLQYFAEPMMLDCGHNICCACLARCWGTAETNVSCPQCRETF 60
           MA  +    LQ E  C +CL Y ++P+ ++CGHN C +C+ + W   +    CP CR   
Sbjct: 1   MAVAAALTGLQAEAKCSICLDYLSDPVTIECGHNFCRSCIQQSWLDLQELFPCPVCRHQC 60

Query: 61  PQRHMRPNRHLANVTQLVKQLR-TERPSGPGGEMGVCEKHREPLKLYCEEDQMPICVVCD 119
            + H R N  L  + ++ K L+ T+       E  +CEKH +PL ++C+ED M +C +C 
Sbjct: 61  QEGHFRSNTQLGRMIEIAKLLQSTKSNKRKQEETTLCEKHNQPLSVFCKEDLMVLCPLCT 120

Query: 120 RSREHRGHSVLPLEEAVEGFKEQIQNQLDHLKR-VKDLKKRRRAQGEQARAELLSLTQME 178
           +  +H+GH V P+E+A   ++++  + +  LK+ + DL+K    Q ++   EL  + + +
Sbjct: 121 QPPDHQGHHVRPIEKAAIHYRKRFCSYIQPLKKQLADLQKLISTQSKKP-LELREMVENQ 179

Query: 179 REKIVWEFEQLYHSLKEHEYRLLARLEELDLAIYNSINGAITQFSCNISHLSSLIAQLEE 238
           R+++  EFE L   L   +  +L+RL E +      ++  IT FS   + L S ++++ E
Sbjct: 180 RQELSSEFEHLNQFLDREQQAVLSRLAEEEKDNQQKLSANITAFSNYSATLKSQLSKVVE 239

Query: 239 KQQQPTRELLQDIGDTLSRAERIRIPEPWITPPDLQEKIHIFAQKCLFLTESLKQFTEKM 298
             +    ELL  I      +E    P  +         IH+    C F  +         
Sbjct: 240 LSELSELELLSQI-KIFYESENESSPSIF--------SIHLKRDGCSFPPQ--------- 281

Query: 299 QSDMEKIQELREAQLYSVDVTLDPDTAYPSLILSDNLRQVRYSYLQQDLPDNPERFNLFP 358
            S +++I      + + V++ LDP+TA+P+LI+S++ ++VR++  +Q +P  P+RF + P
Sbjct: 282 YSALQRI-----IKKFKVEIILDPETAHPNLIVSEDKKRVRFTKRKQKVPGFPKRFTVKP 336

Query: 359 CVLGSPCFIAGRHYWEVEVGDKAKWTIGVCEDSVCRKGGVTSAPQNGFWAVSLWYGKEYW 418
            VLG P F +GRH+WE+EVGDK++W IG+C+DS+  K    S+ Q   W + L     Y 
Sbjct: 337 VVLGFPYFHSGRHFWEIEVGDKSEWAIGICKDSLPTKARRPSSAQQECWRIEL-QDDGYH 395

Query: 419 ALTSPMTALPLRTPLQRVGIFLDYDAGEVSFYNVTERCHTFTFSHATFCGPVRPYFSLSY 478
           A  +  T L L    + +GIFLDY+ GE+SFYN+ E+ H  TF+  TF GP+RPYF +  
Sbjct: 396 APGAFPTPLLLEVKARAIGIFLDYEMGEISFYNMAEKSHICTFTD-TFTGPLRPYFYV-- 452

Query: 479 SGGKSAAPLIIC 490
             G  + PL IC
Sbjct: 453 --GPDSQPLRIC 462


>gi|157426898 tripartite motif-containing 10 isoform 1 [Homo
           sapiens]
          Length = 481

 Score =  276 bits (705), Expect = 4e-74
 Identities = 167/482 (34%), Positives = 259/482 (53%), Gaps = 18/482 (3%)

Query: 1   MASGSVAECLQQETTCPVCLQYFAEPMMLDCGHNICCACLARCWGTA----ETNVSCPQC 56
           MAS +    L  E  CP+C     EP+ +DCGHN C ACL R         E + +CP C
Sbjct: 1   MASAASVTSLADEVNCPICQGTLREPVTIDCGHNFCRACLTRYCEIPGPDLEESPTCPLC 60

Query: 57  RETFPQRHMRPNRHLANVTQLVKQLRTERPSGPGGEMGVCEKHREPLKLYCEEDQMPICV 116
           +E F     RPN  LANV + +++L+     G G E  VC++H E +  +CE+D+M +CV
Sbjct: 61  KEPFRPGSFRPNWQLANVVENIERLQLVSTLGLGEE-DVCQEHGEKIYFFCEDDEMQLCV 119

Query: 117 VCDRSREHRGHSVLPLEEAVEGFKEQIQNQLDHLKRVKDLKKRRRAQGEQARAELLSLTQ 176
           VC  + EH  H++  LE+A   ++EQI   L  L++ ++  +  +++  +    LL+   
Sbjct: 120 VCREAGEHATHTMRFLEDAAAPYREQIHKCLKCLRKEREEIQEIQSRENKRMQVLLTQVS 179

Query: 177 MEREKIVWEFEQLYHSLKEHEYRLLARLEELDLAIYNSINGAITQFSCNISHLSSLIAQL 236
            +R++++ EF  L   L+E +  LLA+LE  D  I    +      +  I   S+LI +L
Sbjct: 180 TKRQQVISEFAHLRKFLEEQQSILLAQLESQDGDILRQRDEFDLLVAGEICRFSALIEEL 239

Query: 237 EEKQQQPTRELLQDIGDTLSRAERIRIPEPWITPPDLQEKIHIFAQKCLFLTESLKQFTE 296
           EEK ++P RELL DI  TL R E  +  +P    P+L ++I  F Q+ L L   +K F E
Sbjct: 240 EEKNERPARELLTDIRSTLIRCETRKCRKPVAVSPELGQRIRDFPQQALPLQREMKMFLE 299

Query: 297 KMQSDMEKIQELREAQLYSVDVTLDPDTAYPSLILSDNLRQVRYSYLQQDLPDNPERFNL 356
           K+  +++              ++LDP T++P L+LS++ ++ ++SY  Q+ PDNP+RF+ 
Sbjct: 300 KLCFELD---------YEPAHISLDPQTSHPKLLLSEDHQRAQFSYKWQNSPDNPQRFDR 350

Query: 357 FPCVLGSPCFIAGRHYW--EVEVGDKAKWTIGVCEDSVCRKGGVTSAPQNGFWAVSLWYG 414
             CVL       GRH W   +++      T+GV  + V RKG +   P+ G WAV L +G
Sbjct: 351 ATCVLAHTGITGGRHTWVVSIDLAHGGSCTVGVVSEDVQRKGELRLRPEEGVWAVRLAWG 410

Query: 415 KEYWALTSPMTALPLRTPLQRVGIFLDYDAGEVSFYNVTERCHTFTFSHATFCGPVRPYF 474
               AL S  T L L+   ++V + LDY+ G V+F N   R   +TF+ A+F   V P+F
Sbjct: 411 -FVSALGSFPTRLTLKEQPRQVRVSLDYEVGWVTFTNAVTREPIYTFT-ASFTRKVIPFF 468

Query: 475 SL 476
            L
Sbjct: 469 GL 470


>gi|22749269 ring finger protein 129 [Homo sapiens]
          Length = 471

 Score =  268 bits (685), Expect = 9e-72
 Identities = 162/488 (33%), Positives = 267/488 (54%), Gaps = 34/488 (6%)

Query: 10  LQQETTCPVCLQYFAEPMMLDCGHNICCACLARCWGTAETNVSCPQCRETFPQRHMRPNR 69
           LQ+E++CP+CL+Y  +P+ ++CGHN C +CL+  W   +    CP CR  FP +  R N 
Sbjct: 10  LQEESSCPICLEYLKDPVTINCGHNFCRSCLSVSWKDLDDTFPCPVCRFCFPYKSFRRNP 69

Query: 70  HLANVTQLVKQLRTERPSGPGG-EMGVCEKHREPLKLYCEEDQMPICVVCDRSREHRGHS 128
            L N+T++ KQL+  R       E  +CEKH + L L+C +D   +C  C  S +H+ H 
Sbjct: 70  QLRNLTEIAKQLQIRRSKRKRQKENAMCEKHNQFLTLFCVKDLEILCTQCSFSTKHQKHY 129

Query: 129 VLPLEEAVEGFKEQIQNQLDHLKR-VKDLKKRRRAQGEQARAELLSLTQMEREKIVWEFE 187
           + P+++A    +E ++  L+ L+  ++ ++K    QG ++  EL    + +RE+I  EFE
Sbjct: 130 ICPIKKAASYHREILEGSLEPLRNNIERVEKVIILQGSKS-VELKKKVEYKREEINSEFE 188

Query: 188 QLYHSLKEHEYRLLARLEELDLAIYNSINGAITQFSCNISHLSSLIAQLEEKQQQPTREL 247
           Q+   L+  +  +L ++++ ++ I   +N  + + S  +S L  L+ ++E K  Q   EL
Sbjct: 189 QIRLFLQNEQEMILRQIQDEEMNILAKLNENLVELSDYVSTLKHLLREVEGKSVQSNLEL 248

Query: 248 LQDIGDTLSRAERIRIPEPWITPPDLQEKIHIFAQKCLFLTESLKQFTEKMQSDMEKIQE 307
           L        + + ++ PE             +F+ +      SL        S +++I  
Sbjct: 249 LTQAKSMHHKYQNLKCPE-------------LFSFRLTKYGFSLPP----QYSGLDRI-- 289

Query: 308 LREAQLYSVDVTLDPDTAYPSLILSDNLRQVRYSYLQQDLPDNPERFNLFPCVLGSPCFI 367
               + + VDV LD +TA+P L++S++ + VRY   ++++  +P RF + P VLGS  F 
Sbjct: 290 ---IKPFQVDVILDLNTAHPQLLVSEDRKAVRYERKKRNICYDPRRFYVCPAVLGSQRFS 346

Query: 368 AGRHYWEVEVGDKAKWTIGVCEDSVCRKGGVTSAPQNGFWAVSLWYGKEYWALTSPMTA- 426
           +GRHYWEVEVG+K KW +GVC+D + R      +   GFWA+   Y K  +  + P T  
Sbjct: 347 SGRHYWEVEVGNKPKWILGVCQDCLLRNWQDQPSVLGGFWAIGR-YMKSGYVASGPKTTQ 405

Query: 427 -LPLRTPLQRVGIFLDYDAGEVSFYNVTERCHTFTFSHATFCGPVRPYFSLSYSGGKSAA 485
            LP+  P  ++GIFLDY+ G++SFYN+ +R   +TF+   F   V PYF   Y+G  S  
Sbjct: 406 LLPVVKP-SKIGIFLDYELGDLSFYNMNDRSILYTFNDC-FTEAVWPYF---YTGTDS-E 459

Query: 486 PLIICPMS 493
           PL IC +S
Sbjct: 460 PLKICSVS 467


>gi|18079262 tripartite motif-containing 6 isoform 2 [Homo sapiens]
          Length = 488

 Score =  268 bits (684), Expect = 1e-71
 Identities = 173/487 (35%), Positives = 256/487 (52%), Gaps = 43/487 (8%)

Query: 10  LQQETTCPVCLQYFAEPMMLDCGHNICCACLARCWGTA----ETNVSCPQCRETFPQRHM 65
           +++E TCP+CL+   EP+ +DCGH+ C AC+      +    E   SCP C+ ++   ++
Sbjct: 9   IREEVTCPICLELLTEPLSIDCGHSFCQACITPNGRESVIGQEGERSCPVCQTSYQPGNL 68

Query: 66  RPNRHLANVTQLVKQLRTERPSGPGGEMG--VCEKHREPLKLYCEEDQMPICVVCDRSRE 123
           RPNRHLAN+   V++LR E   GPG ++   +C  H E L+L+C+ED   IC +C+RS+E
Sbjct: 69  RPNRHLANI---VRRLR-EVVLGPGKQLKAVLCADHGEKLQLFCQEDGKVICWLCERSQE 124

Query: 124 HRGHSVLPLEEAVEGFKEQIQNQLDHLKRVKDLKKRRRAQGEQARAELLSLTQMEREKIV 183
           HRGH    +EE  + ++E+ Q  L  LK  +   ++  A   + +    +  + ER +I 
Sbjct: 125 HRGHHTFLVEEVAQEYQEKFQESLKKLKNEEQEAEKLTAFIREKKTSWKNQMEPERCRIQ 184

Query: 184 WEFEQLYHSLKEHEYRLLARLEELDLAIYNSINGAITQFSCNISHLSSLIAQLEEKQQQP 243
            EF QL + L   E R L +LE+ +      I  A          L  LI+ LE + Q  
Sbjct: 185 TEFNQLRNILDRVEQRELKKLEQEEKKGLRIIEEAENDLVHQTQSLRELISDLERRCQGS 244

Query: 244 TRELLQDIGDTLSRAERIRIPEPWITPPDLQEKIHIFAQKCLFLTESLKQFTEKMQSDME 303
           T ELLQD+ D   R+E   + +P   P  L         + +F    LK+        + 
Sbjct: 245 TMELLQDVSDVTERSEFWTLRKPEALPTKL---------RSMFRAPDLKRM-------LR 288

Query: 304 KIQELREAQLYSVDVTLDPDTAYPSLILSDNLRQVRYSYLQQDLPDNPERFNLFPC-VLG 362
             +EL + Q Y VDVTL+P TA  +L+L+ N RQVR+   +   P   E+   + C VLG
Sbjct: 289 VCRELTDVQSYWVDVTLNPHTANLNLVLAKNRRQVRFVGAKVSGPSCLEKH--YDCSVLG 346

Query: 363 SPCFIAGRHYWEVEVGDKAKWTIGVCEDSV---------CRKGGVTS--APQNGFWAVSL 411
           S  F +G+HYWEV+V  K  W +GVC +S+          +     S   PQ+G+W + L
Sbjct: 347 SQHFSSGKHYWEVDVAKKTAWILGVCSNSLGPTFSFNHFAQNHSAYSRYQPQSGYWVIGL 406

Query: 412 WYGKEYWAL--TSPMTALPLRTPLQRVGIFLDYDAGEVSFYNVTER-CHTFTFSHATFCG 468
            +  EY A   +SP   L +  P +RVG+FLDY+AG VSFYNVT      +TFS   F  
Sbjct: 407 QHNHEYRAYEDSSPSLLLSMTVPPRRVGVFLDYEAGTVSFYNVTNHGFPIYTFSKYYFPT 466

Query: 469 PVRPYFS 475
            + PYF+
Sbjct: 467 TLCPYFN 473


>gi|51477692 tripartite motif-containing 6 isoform 1 [Homo sapiens]
          Length = 516

 Score =  268 bits (684), Expect = 1e-71
 Identities = 173/487 (35%), Positives = 256/487 (52%), Gaps = 43/487 (8%)

Query: 10  LQQETTCPVCLQYFAEPMMLDCGHNICCACLARCWGTA----ETNVSCPQCRETFPQRHM 65
           +++E TCP+CL+   EP+ +DCGH+ C AC+      +    E   SCP C+ ++   ++
Sbjct: 37  IREEVTCPICLELLTEPLSIDCGHSFCQACITPNGRESVIGQEGERSCPVCQTSYQPGNL 96

Query: 66  RPNRHLANVTQLVKQLRTERPSGPGGEMG--VCEKHREPLKLYCEEDQMPICVVCDRSRE 123
           RPNRHLAN+   V++LR E   GPG ++   +C  H E L+L+C+ED   IC +C+RS+E
Sbjct: 97  RPNRHLANI---VRRLR-EVVLGPGKQLKAVLCADHGEKLQLFCQEDGKVICWLCERSQE 152

Query: 124 HRGHSVLPLEEAVEGFKEQIQNQLDHLKRVKDLKKRRRAQGEQARAELLSLTQMEREKIV 183
           HRGH    +EE  + ++E+ Q  L  LK  +   ++  A   + +    +  + ER +I 
Sbjct: 153 HRGHHTFLVEEVAQEYQEKFQESLKKLKNEEQEAEKLTAFIREKKTSWKNQMEPERCRIQ 212

Query: 184 WEFEQLYHSLKEHEYRLLARLEELDLAIYNSINGAITQFSCNISHLSSLIAQLEEKQQQP 243
            EF QL + L   E R L +LE+ +      I  A          L  LI+ LE + Q  
Sbjct: 213 TEFNQLRNILDRVEQRELKKLEQEEKKGLRIIEEAENDLVHQTQSLRELISDLERRCQGS 272

Query: 244 TRELLQDIGDTLSRAERIRIPEPWITPPDLQEKIHIFAQKCLFLTESLKQFTEKMQSDME 303
           T ELLQD+ D   R+E   + +P   P  L         + +F    LK+        + 
Sbjct: 273 TMELLQDVSDVTERSEFWTLRKPEALPTKL---------RSMFRAPDLKRM-------LR 316

Query: 304 KIQELREAQLYSVDVTLDPDTAYPSLILSDNLRQVRYSYLQQDLPDNPERFNLFPC-VLG 362
             +EL + Q Y VDVTL+P TA  +L+L+ N RQVR+   +   P   E+   + C VLG
Sbjct: 317 VCRELTDVQSYWVDVTLNPHTANLNLVLAKNRRQVRFVGAKVSGPSCLEKH--YDCSVLG 374

Query: 363 SPCFIAGRHYWEVEVGDKAKWTIGVCEDSV---------CRKGGVTS--APQNGFWAVSL 411
           S  F +G+HYWEV+V  K  W +GVC +S+          +     S   PQ+G+W + L
Sbjct: 375 SQHFSSGKHYWEVDVAKKTAWILGVCSNSLGPTFSFNHFAQNHSAYSRYQPQSGYWVIGL 434

Query: 412 WYGKEYWAL--TSPMTALPLRTPLQRVGIFLDYDAGEVSFYNVTER-CHTFTFSHATFCG 468
            +  EY A   +SP   L +  P +RVG+FLDY+AG VSFYNVT      +TFS   F  
Sbjct: 435 QHNHEYRAYEDSSPSLLLSMTVPPRRVGVFLDYEAGTVSFYNVTNHGFPIYTFSKYYFPT 494

Query: 469 PVRPYFS 475
            + PYF+
Sbjct: 495 TLCPYFN 501


>gi|42516572 tripartite motif-containing 41 isoform 1 [Homo sapiens]
          Length = 630

 Score =  259 bits (661), Expect = 5e-69
 Identities = 163/471 (34%), Positives = 248/471 (52%), Gaps = 53/471 (11%)

Query: 52  SCPQCRETFPQRHMRPNRHLANVTQLVKQLRTERPSGPG-GEMGVCEKHREPLKLYCEED 110
           +CPQCR++FP+R  RPN  LAN+ Q+++Q+      G    + G+C KH+E LKL+CE D
Sbjct: 182 TCPQCRKSFPRRSFRPNLQLANMVQVIRQMHPTPGRGSRVTDQGICPKHQEALKLFCEVD 241

Query: 111 QMPICVVCDRSREHRGHSVLPLEEAVEGFKEQIQNQLDHLKRVKDLKKRRRAQGEQARAE 170
           +  ICVVC  SR H+ HSV+PLEE V+ +K ++Q  ++ L++  +  ++ +A+ E+   E
Sbjct: 242 EEAICVVCRESRSHKQHSVVPLEEVVQEYKAKLQGHVEPLRKHLEAVQKMKAKEERRVTE 301

Query: 171 LLSLTQMEREKIVWEFEQLYHSLKEHEYRLLARLEELDLAIYNSINGAITQFSCNISHLS 230
           L S  + E   +  EF +L   L E +  L  RL E+  A       A ++ +   + LS
Sbjct: 302 LKSQMKSELAAVASEFGRLTRFLAEEQAGLERRLREMHEAQLGRAGAAASRLAEQAAQLS 361

Query: 231 SLIAQLEEKQQQPTRELLQDIGDTLSRAERIRIPEPWITPPD-LQEKIHIFAQKCLFLTE 289
            L+A+ +E+ QQ    LLQDI +T +R E +++  P +  PD  Q   H       FLT+
Sbjct: 362 RLLAEAQERSQQGGLRLLQDIKETFNRCEEVQLQPPEVWSPDPCQPHSHD------FLTD 415

Query: 290 SLKQFTEKMQSDMEKIQELREAQLYSVDVTLDPDTAYPSLILSDNLRQVRYSYLQQDLPD 349
           ++ +   +M             Q   VD+TLDPDTA+P+L+LS + R VR +  +Q++ D
Sbjct: 416 AIVRKMSRM-----------FCQAARVDLTLDPDTAHPALMLSPDRRGVRLAERRQEVAD 464

Query: 350 NPERFNLFPCVLGSPCFIAGRHYWEVEVGDKAKWTIGVCEDSVCRK------------GG 397
           +P+RF+   CVLG+  F +GRHYWEVEVG +  W +G   +S   K            G 
Sbjct: 465 HPKRFSADCCVLGAQGFRSGRHYWEVEVGGRRGWAVGAARESTHHKEKVGPGGSSVGSGD 524

Query: 398 VTSA-----------PQNGFWAVSLW----YGKEYWALTSPMTAL--PLRTPLQRVGIFL 440
            +S+           PQ       +W     GK Y A +S    L  P   P +R G++L
Sbjct: 525 ASSSRHHHRRRRLHLPQQPLLQREVWCVGTNGKRYQAQSSTEQTLLSPSEKP-RRFGVYL 583

Query: 441 DYDAGEVSFYNVTERCHTFTFSHATFCGPVRPYFSLSYSGGKSAAPLIICP 491
           DY+AG + FYN     H  TFS A     V P+F +   G +    + +CP
Sbjct: 584 DYEAGRLGFYNAETLAHVHTFSAAFLGERVFPFFRVLSKGTR----IKLCP 630



 Score = 53.1 bits (126), Expect = 6e-07
 Identities = 17/38 (44%), Positives = 25/38 (65%)

Query: 8  ECLQQETTCPVCLQYFAEPMMLDCGHNICCACLARCWG 45
          + LQ+E  C +CL YF +P+ + CGHN C  C+ + WG
Sbjct: 12 QTLQEEAVCAICLDYFTDPVSIGCGHNFCRVCVTQLWG 49


>gi|31542779 tripartite motif family-like 1 [Homo sapiens]
          Length = 468

 Score =  255 bits (651), Expect = 8e-68
 Identities = 158/497 (31%), Positives = 257/497 (51%), Gaps = 36/497 (7%)

Query: 1   MASGSVAECLQQETTCPVCLQYFAEPMMLDCGHNICCACLARCWGTAETNVSCPQCRETF 60
           M++  + E L++E TC +CL YF+ P+  +CGH+ C  CL R W    T +SCP+C  T 
Sbjct: 1   MSTADLMENLREELTCFICLDYFSSPVTTECGHSFCLVCLLRSWEEHNTPLSCPECWRTL 60

Query: 61  PQRHMRPNRHLANVTQLVKQLRTERPSGPGGEMGVCEKHREPLKLYCEEDQMPICVVCDR 120
              H + N  L  +  + +QLR++       E G   +     K   +++Q     V   
Sbjct: 61  EGPHFQSNERLGRLASIARQLRSQVLQSED-EQGSYGRMPTTAKALSDDEQGGSAFV--- 116

Query: 121 SREHRGHSVLPLEEAVEGFKEQIQNQLDHLKRVKDLKKRRRAQGEQARAELLSL-TQMER 179
           ++ H  + V    EA E  +E++Q  L+ L RV+  + +     E+ R +L    T+  +
Sbjct: 117 AQSHGANRVHLSSEAEEHHREKLQEILN-LLRVRRKEAQAVLTHEKERVKLCQEETKTCK 175

Query: 180 EKIVWEFEQLYHSLKEHEYRLLARLEELDLAIYNSINGAITQFSCNISHLSSLIAQLEEK 239
           + +V E+ +++  LKE E   L  LE+ +      +     + +  I  LS +IAQ+E  
Sbjct: 176 QVVVSEYMKMHQFLKEEEQLQLQLLEQEEKENMRKLRNNEIKLTQQIRSLSKMIAQIESS 235

Query: 240 QQQPTRELLQDIGDTLSRAERIRIPEPWITPPDLQEKIHIFAQKCLFLTESLKQFTEKMQ 299
            Q    E L+++   L R+E + +  P  T  +L           L     +K+   K  
Sbjct: 236 SQSSAFESLEEVRGALERSEPLLLQCPEATTTELS----------LCRITGMKEMLRK-- 283

Query: 300 SDMEKIQELREAQLYSVDVTLDPDTAYPSLILSDNLRQVRYSYLQQDLPDNPERFNLFPC 359
                         +S ++TLDP TA   L+LS++L+ V+Y   +Q LPDNPERF+    
Sbjct: 284 --------------FSTEITLDPATANAYLVLSEDLKSVKYGGSRQQLPDNPERFDQSAT 329

Query: 360 VLGSPCFIAGRHYWEVEVGDKAKWTIGVCEDSVCRKGGVTSAPQNGFWAVSLWYGKEY-- 417
           VLG+  F +GRHYWEVEVG+K +W +G+C+DSV RKG +   P + F  + L  G +Y  
Sbjct: 330 VLGTQIFTSGRHYWEVEVGNKTEWEVGICKDSVSRKGNLPKPPGDLFSLIGLKIGDDYSL 389

Query: 418 WALTSPMTALPLRTPLQRVGIFLDYDAGEVSFYNVTERCHTFTFSHATFCGPVRPYFSLS 477
           W ++SP+    +R P+ +VG+FLDY++G ++FYN T+    ++F  A+F   +RP FS  
Sbjct: 390 W-VSSPLKGQHVREPVCKVGVFLDYESGHIAFYNGTDESLIYSFPQASFQEALRPIFSPC 448

Query: 478 Y-SGGKSAAPLIICPMS 493
             + G +  PL IC ++
Sbjct: 449 LPNEGTNTDPLTICSLN 465


>gi|15011941 tripartite motif protein TRIM4 isoform beta [Homo
           sapiens]
          Length = 474

 Score =  251 bits (642), Expect = 8e-67
 Identities = 168/514 (32%), Positives = 250/514 (48%), Gaps = 72/514 (14%)

Query: 7   AECLQQETTCPVCLQYFAEPMMLDCGHNICCACLARCWGTAETNVSCPQCRETFPQRHMR 66
           AE +Q+E TCP+CL YF +P+ ++CGHN C  CL R W        CP+CR       +R
Sbjct: 3   AEDIQEELTCPICLDYFQDPVSIECGHNFCRGCLHRNWAPGGGPFPCPECRHPSAPAALR 62

Query: 67  PNRHLANVTQLVKQLRTERPSGPGGEMGVCEKHREPLKLYCEEDQMPICVVCDRSREHRG 126
           PN  LA +T+   Q R   P  P    G+C +H EPL+L+CE+DQ P+C+VC  S+EH+ 
Sbjct: 63  PNWALARLTEKT-QRRRLGPVPP----GLCGRHWEPLRLFCEDDQRPVCLVCRESQEHQT 117

Query: 127 HSVLPLEEAVEGFKEQI----QNQLDHLKRVKDLKKRRRAQGEQARAELLSLTQMEREKI 182
           H++ P++EA E ++E++    +N +  +K+V  L+        Q + ++ S    +R +I
Sbjct: 118 HAMAPIDEAFESYREKLLKSQRNLVAKMKKVMHLQDVEVKNATQWKDKIKS----QRMRI 173

Query: 183 VWEFEQLYHSLKEHEYRLLARLEELDLAIYNSINGAITQFSCNISHLSSLIAQLEEKQQQ 242
             EF +L++ L E E   L RL + +      +N    + +  I+ L  LI ++ EK Q 
Sbjct: 174 STEFSKLHNFLVEEEDLFLQRLNKEEEETKKKLNENTLKLNQTIASLKKLILEVGEKSQA 233

Query: 243 PTRELLQDIGDTLSRAERIRIPEPWITPPDLQEKIHIFAQKCLFLTESLKQFTEKMQSDM 302
           PT ELLQ+  + L+R+E            D+   +     K +     +K+  ++ Q   
Sbjct: 234 PTLELLQNPKEVLTRSE----------IQDVNYSLEAVKVKTVCQIPLMKEMLKRFQ--- 280

Query: 303 EKIQELREAQLYSVDVTLDPDTAYPSLILSDNLRQVRYSYLQQDLP------------DN 350
                        V V L  DTA+P L+ S   R V+ +      P             N
Sbjct: 281 -------------VAVNLAEDTAHPKLVFSQEGRYVKNTASASSWPVFSSAWNYFAGWRN 327

Query: 351 P------ERFNLFPCVLGSPCFIAGRHYWEVEVGDKAKWTIGVCEDSVCRKGGVTS---- 400
           P      ERF   PCVLG   F +G+HYWEVE  D  +  +GVC + V    G+T     
Sbjct: 328 PQKTAFVERFQHLPCVLGKNVFTSGKHYWEVESRDSLEVAVGVCREDVM---GITDRSKM 384

Query: 401 APQNGFWAVSLWYGKEYWALTS-PMTALPLRTPLQRVGIFLDYDAGEVSFYNVTERCHTF 459
           +P  G WA+  W    YW L   P T       L RVG++LD   G VSFY+  +  H  
Sbjct: 385 SPDVGIWAI-YWSAAGYWPLIGFPGTPTQQEPALHRVGVYLDRGTGNVSFYSAVDGVHLH 443

Query: 460 TFSHATFCGPVRPYFSLSYSGGKSAAPLIICPMS 493
           TFS  +    +RP+F LS       A L+I P++
Sbjct: 444 TFS-CSSVSRLRPFFWLS-----PLASLVIPPVT 471


>gi|149193331 tripartite motif protein 15 [Homo sapiens]
          Length = 465

 Score =  249 bits (637), Expect = 3e-66
 Identities = 159/471 (33%), Positives = 253/471 (53%), Gaps = 34/471 (7%)

Query: 16  CPVCLQYFAEPMMLDCGHNICCACLARC--WGTAETN--VSCPQCRETFPQRHMRPNRHL 71
           C +C     + + + CGH  C  CL      G   +   + CP C+E       +    +
Sbjct: 16  CTLCAGPLEDAVTIPCGHTFCRLCLPALSQMGAQSSGKILLCPLCQE-----EEQAETPM 70

Query: 72  ANVTQLVKQLRTERPSGPGGEMGVCEKHREPLKLYCEEDQMPICVVCDRSREHRGHSVLP 131
           A V           P GP GE   CE+H E +  +CE D   +CV C     H+ H+V  
Sbjct: 71  APV-----------PLGPLGET-YCEEHGEKIYFFCENDAEFLCVFCREGPTHQAHTVGF 118

Query: 132 LEEAVEGFKEQIQNQLDHLKRVKDLKKRRRAQGEQARAELLSLTQMEREKIVWEFEQLYH 191
           L+EA++ ++++++++L+ L   +D  +  + Q +Q    LL+  + ++ ++   FE+L  
Sbjct: 119 LDEAIQPYRDRLRSRLEALSTERDEIEDVKCQEDQKLQVLLTQIESKKHQVETAFERLQQ 178

Query: 192 SLKEHEYRLLARLEELDLAIYNSINGAITQFSCNISHLSSLIAQLEEKQQQPTRELLQDI 251
            L++    LLARL EL+  I+   +  IT+ S  ++ L + + +LEEK QQP  ELLQD+
Sbjct: 179 ELEQQRCLLLARLRELEQQIWKERDEYITKVSEEVTRLGAQVKELEEKCQQPASELLQDV 238

Query: 252 GDTLSRAERIRIPEPWITPPDLQEKIHIFAQKCLFLTESLKQFTEKMQSDMEKIQELREA 311
               SR E      P    PDL +KI  F +K L L E ++ F+E +   +E        
Sbjct: 239 RVNQSRCEMKTFVSPEAISPDLVKKIRDFHRKILTLPEMMRMFSENLAHHLE-------- 290

Query: 312 QLYSVDVTLDPDTAYPSLILSDNLRQVRYSYLQQDLPDNPERFNLFPCVLGSPCFIAGRH 371
            + S  +TLDP TA  SL+LS++ + VRY+  ++ LPD+P RF+  P VLG P F +GRH
Sbjct: 291 -IDSGVITLDPQTASRSLVLSEDRKSVRYTRQKKSLPDSPLRFDGLPAVLGFPGFSSGRH 349

Query: 372 YWEV--EVGDKAKWTIGVCEDSVCRKGGVTSAPQNGFWAVSLWYGKEYWALTSPMTALPL 429
            W+V  ++GD    T+GV  + V RKG +  + ++G WAV + + ++ WA TSP T LPL
Sbjct: 350 RWQVDLQLGDGGGCTVGVAGEGVRRKGEMGLSAEDGVWAVIISH-QQCWASTSPGTDLPL 408

Query: 430 RTPLQRVGIFLDYDAGEVSFYNVTERCHTFTFSHATFCGPVRPYFSLSYSG 480
               + V + LDY+AG+V+ +N   +   FTF+ A+F G V P+F++   G
Sbjct: 409 SEIPRGVRVALDYEAGQVTLHNAQTQEPIFTFT-ASFSGKVFPFFAVWKKG 458


>gi|14719418 tripartite motif protein TRIM5 isoform alpha [Homo
           sapiens]
          Length = 493

 Score =  244 bits (624), Expect = 1e-64
 Identities = 163/517 (31%), Positives = 256/517 (49%), Gaps = 49/517 (9%)

Query: 1   MASGSVAECLQQETTCPVCLQYFAEPMMLDCGHNICCACLARCWGTA---ETNVSCPQCR 57
           MASG +   +++E TCP+CL+   +P+ LDCGH+ C ACL      +   +   SCP CR
Sbjct: 1   MASGILVN-VKEEVTCPICLELLTQPLSLDCGHSFCQACLTANHKKSMLDKGESSCPVCR 59

Query: 58  ETFPQRHMRPNRHLANVTQLVKQLRTERPSGPGGEMGVCEKHREPLKLYCEEDQMPICVV 117
            ++   ++RPNRH+AN   LV++LR  + S  G ++  C +H E L L+C+ED   IC +
Sbjct: 60  ISYQPENIRPNRHVAN---LVEKLREVKLSPEGQKVDHCARHGEKLLLFCQEDGKVICWL 116

Query: 118 CDRSREHRGHSVLPLEEAVEGFKEQIQNQLDHLKRVKDLKKRRRAQGEQARAELLSLTQM 177
           C+RS+EHRGH   P EE  + ++ ++Q  L+ L++ +   +   A   + +A   +  Q 
Sbjct: 117 CERSQEHRGHHTFPTEEVAQEYQVKLQAALEMLRQKQQEAEELEADIREEKASWKTQIQY 176

Query: 178 EREKIVWEFEQLYHSLKEHEYRLLARLEELDLAIYNSINGAITQFSCNISHLSSLIAQLE 237
           ++  ++ +FEQL   L   E   L  LE+ +  I  S+  + T+       L  LI+ LE
Sbjct: 177 DKTNVLADFEQLRDILDWEESNELQNLEKEEEDILKSLTNSETEMVQQTQSLRELISDLE 236

Query: 238 EKQQQPTRELLQDIGDTLSRAERIRIPEPWITPPDLQEKIHIFAQKCLFLTESLKQFTEK 297
            + Q    ELLQ +   + R E + + +P   P +         Q+ +F    LK     
Sbjct: 237 HRLQGSVMELLQGVDGVIKRTENVTLKKPETFPKN---------QRRVFRAPDLKGM--- 284

Query: 298 MQSDMEKIQELREAQLYSVDVTLDPDTAYPSLILSDNLRQVRYSYLQQDLPDNPER---- 353
               +E  +EL + + Y VDVT+ P+      ++S++ RQV     Q        R    
Sbjct: 285 ----LEVFRELTDVRRYWVDVTVAPNN-ISCAVISEDKRQVSSPKPQIIYGARGTRYQTF 339

Query: 354 --FNLFPCVLGSPCFIAGRHYWEVEVGDKAKWTIGVC----EDSVCR-KGGVTSAPQNGF 406
             FN    +LGS    +G+HYWEV+V  K  W +GVC     D++C  +      P+ G+
Sbjct: 340 VNFNYCTGILGSQSITSGKHYWEVDVSKKTAWILGVCAGFQPDAMCNIEKNENYQPKYGY 399

Query: 407 WAVSLWYGKEYWALTSP---MTALPLRTPL------QRVGIFLDYDAGEVSFYNVTERCH 457
           W + L  G +  A         ++P   PL       RVG+FLDY+A  VSF+N+T    
Sbjct: 400 WVIGLEEGVKCSAFQDSSFHTPSVPFIVPLSVIICPDRVGVFLDYEACTVSFFNITNHGF 459

Query: 458 -TFTFSHATFCGPVRPYFSLSYSGGKSAAPLIICPMS 493
             + FSH +F  PV PY     +  K   P+ +C  S
Sbjct: 460 LIYKFSHCSFSQPVFPYL----NPRKCGVPMTLCSPS 492


>gi|14670266 tripartite motif protein TRIM4 isoform alpha [Homo
           sapiens]
          Length = 500

 Score =  241 bits (616), Expect = 9e-64
 Identities = 171/536 (31%), Positives = 251/536 (46%), Gaps = 90/536 (16%)

Query: 7   AECLQQETTCPVCLQYFAEPMMLDCGHNICCACLARCWGTAETNVSCPQCRETFPQRHMR 66
           AE +Q+E TCP+CL YF +P+ ++CGHN C  CL R W        CP+CR       +R
Sbjct: 3   AEDIQEELTCPICLDYFQDPVSIECGHNFCRGCLHRNWAPGGGPFPCPECRHPSAPAALR 62

Query: 67  PNRHLANVTQLVKQLRTERPSGPGGEMGVCEKHREPLKLYCEEDQMPICVVCDRSREHRG 126
           PN  LA +T+   Q R   P  P    G+C +H EPL+L+CE+DQ P+C+VC  S+EH+ 
Sbjct: 63  PNWALARLTEKT-QRRRLGPVPP----GLCGRHWEPLRLFCEDDQRPVCLVCRESQEHQT 117

Query: 127 HSVLPLEEAVEGF-------------KEQIQNQLDHLKRVKDLKKRRRAQGEQAR----- 168
           H++ P++EA E +             +  I+  L H K+ + L K +R    + +     
Sbjct: 118 HAMAPIDEAFESYRTGNFDIHVDEWKRRLIRLLLYHSKQEEKLLKSQRNLVAKMKKVMHL 177

Query: 169 --AELLSLTQ------MEREKIVWEFEQLYHSLKEHEYRLLARLEELDLAIYNSINGAIT 220
              E+ + TQ       +R +I  EF +L++ L E E   L RL + +      +N    
Sbjct: 178 QDVEVKNATQWKDKIKSQRMRISTEFSKLHNFLVEEEDLFLQRLNKEEEETKKKLNENTL 237

Query: 221 QFSCNISHLSSLIAQLEEKQQQPTRELLQDIGDTLSRAERIRIPEPWITPPDLQEKIHIF 280
           + +  I+ L  LI ++ EK Q PT ELLQ+  + L+R+E            D+   +   
Sbjct: 238 KLNQTIASLKKLILEVGEKSQAPTLELLQNPKEVLTRSE----------IQDVNYSLEAV 287

Query: 281 AQKCLFLTESLKQFTEKMQSDMEKIQELREAQLYSVDVTLDPDTAYPSLILSDNLRQVRY 340
             K +     +K+  ++ Q                V V L  DTA+P L+ S   R V+ 
Sbjct: 288 KVKTVCQIPLMKEMLKRFQ----------------VAVNLAEDTAHPKLVFSQEGRYVKN 331

Query: 341 SYLQQDLP------------DNP------ERFNLFPCVLGSPCFIAGRHYWEVEVGDKAK 382
           +      P             NP      ERF   PCVLG   F +G+HYWEVE  D  +
Sbjct: 332 TASASSWPVFSSAWNYFAGWRNPQKTAFVERFQHLPCVLGKNVFTSGKHYWEVESRDSLE 391

Query: 383 WTIGVCEDSVCRKGGVTS----APQNGFWAVSLWYGKEYWALTS-PMTALPLRTPLQRVG 437
             +GVC + V    G+T     +P  G WA+  W    YW L   P T       L RVG
Sbjct: 392 VAVGVCREDVM---GITDRSKMSPDVGIWAI-YWSAAGYWPLIGFPGTPTQQEPALHRVG 447

Query: 438 IFLDYDAGEVSFYNVTERCHTFTFSHATFCGPVRPYFSLSYSGGKSAAPLIICPMS 493
           ++LD   G VSFY+  +  H  TFS  +    +RP+F LS       A L+I P++
Sbjct: 448 VYLDRGTGNVSFYSAVDGVHLHTFS-CSSVSRLRPFFWLS-----PLASLVIPPVT 497


>gi|4508005 tripartite motif-containing 26 [Homo sapiens]
          Length = 539

 Score =  241 bits (616), Expect = 9e-64
 Identities = 169/546 (30%), Positives = 270/546 (49%), Gaps = 80/546 (14%)

Query: 1   MASGSVAECLQQETTCPVCLQYFAEPMMLDCGHNICCACLARCWGTAETNVSCPQCRETF 60
           MA+ +    L++E TC +CL Y  +P+ +DCGH  C +C       + +   CP C++ F
Sbjct: 1   MATSAPLRSLEEEVTCSICLDYLRDPVTIDCGHVFCRSCTTDVRPISGSRPVCPLCKKPF 60

Query: 61  PQRHMRPNRHLANVTQLVKQLRTERPSGPGG------EMGVCEKHREPLKLYCEEDQMPI 114
            + ++RP   LA++ + +++L+ ++   PG       +  +CE+HRE L  YCE+D   +
Sbjct: 61  KKENIRPVWQLASLVENIERLKVDKGRQPGEVTREQQDAKLCERHREKLHYYCEDDGKLL 120

Query: 115 CVVCDRSREHRGHSVLPLEEAVEGFKEQIQNQLDHLKRVKDLKKRRRAQGEQARAELLSL 174
           CV+C  SREHR H+ + +E+A +  +E+I N L  L+R +D  +  +A+GE      L  
Sbjct: 121 CVMCRESREHRPHTAVLMEKAAQPHREKILNHLSTLRRDRDKIQGFQAKGEADILAALKK 180

Query: 175 TQMEREKIVWEFEQLYHSLKEHEYRLLARLEELDLAIYNSINGAITQFSCNISHLSSLIA 234
            Q +R+ IV EFEQ +  L+E E  LL +L +L+  +        ++    ++ L+ +I+
Sbjct: 181 LQDQRQYIVAEFEQGHQFLREREEHLLEQLAKLEQELTEGREKFKSRGVGELARLALVIS 240

Query: 235 QLEEKQQQPTRELLQDIGDTLSRAERIRIPEPWITPP---DLQEKIHIFAQKCLFLTESL 291
           +LE K QQP  EL+QD  D L+R  R +    W+  P    +++K   F+ K L L   L
Sbjct: 241 ELEGKAQQPAAELMQDTRDFLNRYPRKKF---WVGKPIARVVKKKTGEFSDKLLSLQRGL 297

Query: 292 KQFTEKMQSDMEKIQELREAQLYSVDVTLDPDTAYPSLILSDNLRQVRYSYLQQDLPDNP 351
           ++F  K+         LR+ +  +V VTLDP +A   L LS++ + V Y+ L +    +P
Sbjct: 298 REFQGKL---------LRDLEYKTVSVTLDPQSASGYLQLSEDWKCVTYTSLYKSAYLHP 348

Query: 352 ERFNLFPCVLGSPCFIAGRHYWEVEV-----------GDKAK------------------ 382
           ++F+  P VLGS  F  G+ YWEVEV           GD+ +                  
Sbjct: 349 QQFDCEPGVLGSKGFTWGKVYWEVEVEREGWSEDEEEGDEEEEGEEEEEEEEAGYGDGYD 408

Query: 383 -WTIGVCEDS---------------------------VCRKGGVTSAPQNGFWAVSLWYG 414
            W     E+S                           V RKG ++  P++G WA+ L   
Sbjct: 409 DWETDEDEESLGDEEEEEEEEEEEVLESCMVGVARDSVKRKGDLSLRPEDGVWALRL-SS 467

Query: 415 KEYWALTSPMTALPLRTPLQRVGIFLDYDAGEVSFYNVTERCHTFTFSHATFCGPVRPYF 474
              WA TSP   L      +RVGI LDY+ G V+F N   +   +TF+ ATF   + P+ 
Sbjct: 468 SGIWANTSPEAELFPALRPRRVGIALDYEGGTVTFTNAESQELIYTFT-ATFTRRLVPFL 526

Query: 475 SLSYSG 480
            L + G
Sbjct: 527 WLKWPG 532


>gi|117938316 tripartite motif-containing 22 [Homo sapiens]
          Length = 498

 Score =  236 bits (603), Expect = 3e-62
 Identities = 159/517 (30%), Positives = 253/517 (48%), Gaps = 51/517 (9%)

Query: 5   SVAECLQQETTCPVCLQYFAEPMMLDCGHNICCACLA----RCWGTAETNVSCPQCRETF 60
           SV   +++E TCP+CL+   EP+ LDCGH+ C AC+          +    SCP C+  F
Sbjct: 4   SVKVDIEKEVTCPICLELLTEPLSLDCGHSFCQACITAKIKESVIISRGESSCPVCQTRF 63

Query: 61  PQRHMRPNRHLANVTQLVKQLRTERPSGPGGEMGVCEKHREPLKLYCEEDQMPICVVCDR 120
              ++RPNRHLAN+ + VK+++     G   +  VCE H + L+++C+ED   IC VC+ 
Sbjct: 64  QPGNLRPNRHLANIVERVKEVKMSPQEGQ--KRDVCEHHGKKLQIFCKEDGKVICWVCEL 121

Query: 121 SREHRGHSVLPLEEAVEGFKEQIQNQLDHLKRVKDLKKRRRAQGEQARAELLSLTQMERE 180
           S+EH+GH    + E V+  +E++Q  L  L +     ++      Q R    +  Q+ER+
Sbjct: 122 SQEHQGHQTFRINEVVKECQEKLQVALQRLIKEDQEAEKLEDDIRQERTAWKNYIQIERQ 181

Query: 181 KIVWEFEQLYHSLKEHEYRLLARLEELDLAIYNSINGAITQFSCNISHLSSLIAQLEEKQ 240
           KI+  F ++   L   E R L +LEE ++ + +++  A  Q        S+LI+ L+ + 
Sbjct: 182 KILKGFNEMRVILDNEEQRELQKLEEGEVNVLDNLAAATDQLVQQRQDASTLISDLQRRL 241

Query: 241 QQPTRELLQDIGDTLSRAERIRIPEPWITPPDLQEKIHIFAQKCLFLTESLKQFTEKMQS 300
           +  + E+LQD+ D + R+E   + +    P  + +K+     K +F    L         
Sbjct: 242 RGSSVEMLQDVIDVMKRSESWTLKK----PKSVSKKL-----KSVFRVPDLSGM------ 286

Query: 301 DMEKIQELREAQLYSVDVTLDPDTAYPSLILSDNLRQVRYSYLQQDLPDNPERFNLFPCV 360
            ++ ++EL + Q Y VDV L+P +A  ++ +S + RQV+          NP  F+ F  V
Sbjct: 287 -LQVLKELTDVQYYWVDVMLNPGSATSNVAISVDQRQVKTVRTCTFKNSNPCDFSAFG-V 344

Query: 361 LGSPCFIAGRHYWEVEVGDKAKWTIGV---------------CEDSVCRKGGVTS--APQ 403
            G   F +G++YWEV+V  K  W +GV                 D       V S   PQ
Sbjct: 345 FGCQYFSSGKYYWEVDVSGKIAWILGVHSKISSLNKRKSSGFAFDPSVNYSKVYSRYRPQ 404

Query: 404 NGFWAVSLWYGKEYWALTSPMTALP------LRTPLQRVGIFLDYDAGEVSFYNVTER-C 456
            G+W + L    EY A     ++ P      +  P  R+G+FLDY+AG VSF+NVT    
Sbjct: 405 YGYWVIGLQNTCEYNAFEDSSSSDPKVLTLFMAVPPCRIGVFLDYEAGIVSFFNVTNHGA 464

Query: 457 HTFTFSHATFCGPVRPYFSLSYSGGKSAAPLIICPMS 493
             + FS   F  P  PYF    +      P+ +CP S
Sbjct: 465 LIYKFSGCRFSRPAYPYF----NPWNCLVPMTVCPPS 497


>gi|51477687 tripartite motif protein 34 isoform 1 [Homo sapiens]
          Length = 488

 Score =  235 bits (600), Expect = 6e-62
 Identities = 164/512 (32%), Positives = 253/512 (49%), Gaps = 61/512 (11%)

Query: 10  LQQETTCPVCLQYFAEPMMLDCGHNICCACLARCWGTAETNV----SCPQCRETFPQRHM 65
           +Q+E TCP+CL+   EP+ LDCGH++C AC+      A T++    SCP C  ++   H+
Sbjct: 9   VQEEVTCPICLELLTEPLSLDCGHSLCRACITVSNKEAVTSMGGKSSCPVCGISYSFEHL 68

Query: 66  RPNRHLANVTQLVKQLRTERPSGPGGEMGVCEKHREPLKLYCEEDQMPICVVCDRSREHR 125
           + N+HLAN+ + +K+++    +G   ++  C+ H E L L+C+ED+  IC +C+RS+EHR
Sbjct: 69  QANQHLANIVERLKEVKLSPDNGKKRDL--CDHHGEKLLLFCKEDRKVICWLCERSQEHR 126

Query: 126 GHSVLPLEEAVEGFKEQIQNQLDHLKRVKDLKKRRRAQGEQARAELLSLTQMEREKIVWE 185
           GH  +  EE  +  +E++Q  L  LK+ ++  ++  A   + +       Q ER++I  E
Sbjct: 127 GHHTVLTEEVFKECQEKLQAVLKRLKKEEEEAEKLEADIREEKTSWKYQVQTERQRIQTE 186

Query: 186 FEQLYHSLKEHEYRLLARLEELDLAIYNSINGAITQFSCNISHLSSLIAQLEEKQQQPTR 245
           F+QL   L   E R L RLEE +    +    A  +       +  LI+ +E + Q  T 
Sbjct: 187 FDQLRSILNNEEQRELQRLEEEEKKTLDKFAEAEDELVQQKQLVRELISDVECRSQWSTM 246

Query: 246 ELLQDIGDTLSRAERIRIPEPWITPPDLQEKIHIFAQKCLFLTESLKQFTEKMQSDMEKI 305
           ELLQD+   +  +E  R+ +P +    L+   H                   +   ++  
Sbjct: 247 ELLQDMSGIMKWSEIWRLKKPKMVSKKLKTVFH----------------APDLSRMLQMF 290

Query: 306 QELREAQLYSVDVTLDPDTAYPSLILSDNLRQVRYSYLQQDLPDNPERFNLFPC----VL 361
           +EL   + Y VDVTL+      +L+LS++ RQV        +P  P     F C    VL
Sbjct: 291 RELTAVRCYWVDVTLNSVNLNLNLVLSEDQRQV------ISVPIWP-----FQCYNYGVL 339

Query: 362 GSPCFIAGRHYWEVEVGDKAKWTIGV-CE------DSVCRKGG------VTSAPQNGFWA 408
           GS  F +G+HYWEV+V  K  W +GV C         V R+            P  G+W 
Sbjct: 340 GSQYFSSGKHYWEVDVSKKTAWILGVYCRTYSRHMKYVVRRCANRQNLYTKYRPLFGYWV 399

Query: 409 VSLW----YGKEYWALTS--PMTALPLRTPLQRVGIFLDYDAGEVSFYNVTER-CHTFTF 461
           + L     YG    +L+S   +  L +  P  RVG+FLDY+AG VSF+NVT      + F
Sbjct: 400 IGLQNKCKYGVFEESLSSDPEVLTLSMAVPPCRVGVFLDYEAGIVSFFNVTSHGSLIYKF 459

Query: 462 SHATFCGPVRPYFSLSYSGGKSAAPLIICPMS 493
           S   F  PV PYF    +     AP+ +CP S
Sbjct: 460 SKCCFSQPVYPYF----NPWNCPAPMTLCPPS 487


>gi|18087807 tripartite motif protein 34 isoform 1 [Homo sapiens]
          Length = 488

 Score =  235 bits (600), Expect = 6e-62
 Identities = 164/512 (32%), Positives = 253/512 (49%), Gaps = 61/512 (11%)

Query: 10  LQQETTCPVCLQYFAEPMMLDCGHNICCACLARCWGTAETNV----SCPQCRETFPQRHM 65
           +Q+E TCP+CL+   EP+ LDCGH++C AC+      A T++    SCP C  ++   H+
Sbjct: 9   VQEEVTCPICLELLTEPLSLDCGHSLCRACITVSNKEAVTSMGGKSSCPVCGISYSFEHL 68

Query: 66  RPNRHLANVTQLVKQLRTERPSGPGGEMGVCEKHREPLKLYCEEDQMPICVVCDRSREHR 125
           + N+HLAN+ + +K+++    +G   ++  C+ H E L L+C+ED+  IC +C+RS+EHR
Sbjct: 69  QANQHLANIVERLKEVKLSPDNGKKRDL--CDHHGEKLLLFCKEDRKVICWLCERSQEHR 126

Query: 126 GHSVLPLEEAVEGFKEQIQNQLDHLKRVKDLKKRRRAQGEQARAELLSLTQMEREKIVWE 185
           GH  +  EE  +  +E++Q  L  LK+ ++  ++  A   + +       Q ER++I  E
Sbjct: 127 GHHTVLTEEVFKECQEKLQAVLKRLKKEEEEAEKLEADIREEKTSWKYQVQTERQRIQTE 186

Query: 186 FEQLYHSLKEHEYRLLARLEELDLAIYNSINGAITQFSCNISHLSSLIAQLEEKQQQPTR 245
           F+QL   L   E R L RLEE +    +    A  +       +  LI+ +E + Q  T 
Sbjct: 187 FDQLRSILNNEEQRELQRLEEEEKKTLDKFAEAEDELVQQKQLVRELISDVECRSQWSTM 246

Query: 246 ELLQDIGDTLSRAERIRIPEPWITPPDLQEKIHIFAQKCLFLTESLKQFTEKMQSDMEKI 305
           ELLQD+   +  +E  R+ +P +    L+   H                   +   ++  
Sbjct: 247 ELLQDMSGIMKWSEIWRLKKPKMVSKKLKTVFH----------------APDLSRMLQMF 290

Query: 306 QELREAQLYSVDVTLDPDTAYPSLILSDNLRQVRYSYLQQDLPDNPERFNLFPC----VL 361
           +EL   + Y VDVTL+      +L+LS++ RQV        +P  P     F C    VL
Sbjct: 291 RELTAVRCYWVDVTLNSVNLNLNLVLSEDQRQV------ISVPIWP-----FQCYNYGVL 339

Query: 362 GSPCFIAGRHYWEVEVGDKAKWTIGV-CE------DSVCRKGG------VTSAPQNGFWA 408
           GS  F +G+HYWEV+V  K  W +GV C         V R+            P  G+W 
Sbjct: 340 GSQYFSSGKHYWEVDVSKKTAWILGVYCRTYSRHMKYVVRRCANRQNLYTKYRPLFGYWV 399

Query: 409 VSLW----YGKEYWALTS--PMTALPLRTPLQRVGIFLDYDAGEVSFYNVTER-CHTFTF 461
           + L     YG    +L+S   +  L +  P  RVG+FLDY+AG VSF+NVT      + F
Sbjct: 400 IGLQNKCKYGVFEESLSSDPEVLTLSMAVPPCRVGVFLDYEAGIVSFFNVTSHGSLIYKF 459

Query: 462 SHATFCGPVRPYFSLSYSGGKSAAPLIICPMS 493
           S   F  PV PYF    +     AP+ +CP S
Sbjct: 460 SKCCFSQPVYPYF----NPWNCPAPMTLCPPS 487


>gi|51477690 tripartite motif-containing 6 and tripartite
           motif-containing 34 [Homo sapiens]
          Length = 842

 Score =  235 bits (600), Expect = 6e-62
 Identities = 164/512 (32%), Positives = 253/512 (49%), Gaps = 61/512 (11%)

Query: 10  LQQETTCPVCLQYFAEPMMLDCGHNICCACLARCWGTAETNV----SCPQCRETFPQRHM 65
           +Q+E TCP+CL+   EP+ LDCGH++C AC+      A T++    SCP C  ++   H+
Sbjct: 363 VQEEVTCPICLELLTEPLSLDCGHSLCRACITVSNKEAVTSMGGKSSCPVCGISYSFEHL 422

Query: 66  RPNRHLANVTQLVKQLRTERPSGPGGEMGVCEKHREPLKLYCEEDQMPICVVCDRSREHR 125
           + N+HLAN+ + +K+++    +G   ++  C+ H E L L+C+ED+  IC +C+RS+EHR
Sbjct: 423 QANQHLANIVERLKEVKLSPDNGKKRDL--CDHHGEKLLLFCKEDRKVICWLCERSQEHR 480

Query: 126 GHSVLPLEEAVEGFKEQIQNQLDHLKRVKDLKKRRRAQGEQARAELLSLTQMEREKIVWE 185
           GH  +  EE  +  +E++Q  L  LK+ ++  ++  A   + +       Q ER++I  E
Sbjct: 481 GHHTVLTEEVFKECQEKLQAVLKRLKKEEEEAEKLEADIREEKTSWKYQVQTERQRIQTE 540

Query: 186 FEQLYHSLKEHEYRLLARLEELDLAIYNSINGAITQFSCNISHLSSLIAQLEEKQQQPTR 245
           F+QL   L   E R L RLEE +    +    A  +       +  LI+ +E + Q  T 
Sbjct: 541 FDQLRSILNNEEQRELQRLEEEEKKTLDKFAEAEDELVQQKQLVRELISDVECRSQWSTM 600

Query: 246 ELLQDIGDTLSRAERIRIPEPWITPPDLQEKIHIFAQKCLFLTESLKQFTEKMQSDMEKI 305
           ELLQD+   +  +E  R+ +P +    L+   H                   +   ++  
Sbjct: 601 ELLQDMSGIMKWSEIWRLKKPKMVSKKLKTVFH----------------APDLSRMLQMF 644

Query: 306 QELREAQLYSVDVTLDPDTAYPSLILSDNLRQVRYSYLQQDLPDNPERFNLFPC----VL 361
           +EL   + Y VDVTL+      +L+LS++ RQV        +P  P     F C    VL
Sbjct: 645 RELTAVRCYWVDVTLNSVNLNLNLVLSEDQRQV------ISVPIWP-----FQCYNYGVL 693

Query: 362 GSPCFIAGRHYWEVEVGDKAKWTIGV-CE------DSVCRKGG------VTSAPQNGFWA 408
           GS  F +G+HYWEV+V  K  W +GV C         V R+            P  G+W 
Sbjct: 694 GSQYFSSGKHYWEVDVSKKTAWILGVYCRTYSRHMKYVVRRCANRQNLYTKYRPLFGYWV 753

Query: 409 VSLW----YGKEYWALTS--PMTALPLRTPLQRVGIFLDYDAGEVSFYNVTER-CHTFTF 461
           + L     YG    +L+S   +  L +  P  RVG+FLDY+AG VSF+NVT      + F
Sbjct: 754 IGLQNKCKYGVFEESLSSDPEVLTLSMAVPPCRVGVFLDYEAGIVSFFNVTSHGSLIYKF 813

Query: 462 SHATFCGPVRPYFSLSYSGGKSAAPLIICPMS 493
           S   F  PV PYF    +     AP+ +CP S
Sbjct: 814 SKCCFSQPVYPYF----NPWNCPAPMTLCPPS 841



 Score =  159 bits (402), Expect = 6e-39
 Identities = 94/271 (34%), Positives = 145/271 (53%), Gaps = 10/271 (3%)

Query: 10  LQQETTCPVCLQYFAEPMMLDCGHNICCACLARCWGTA----ETNVSCPQCRETFPQRHM 65
           +++E TCP+CL+   EP+ +DCGH+ C AC+      +    E   SCP C+ ++   ++
Sbjct: 37  IREEVTCPICLELLTEPLSIDCGHSFCQACITPNGRESVIGQEGERSCPVCQTSYQPGNL 96

Query: 66  RPNRHLANVTQLVKQLRTERPSGPGGEMG--VCEKHREPLKLYCEEDQMPICVVCDRSRE 123
           RPNRHLAN+   V++LR E   GPG ++   +C  H E L+L+C+ED   IC +C+RS+E
Sbjct: 97  RPNRHLANI---VRRLR-EVVLGPGKQLKAVLCADHGEKLQLFCQEDGKVICWLCERSQE 152

Query: 124 HRGHSVLPLEEAVEGFKEQIQNQLDHLKRVKDLKKRRRAQGEQARAELLSLTQMEREKIV 183
           HRGH    +EE  + ++E+ Q  L  LK  +   ++  A   + +    +  + ER +I 
Sbjct: 153 HRGHHTFLVEEVAQEYQEKFQESLKKLKNEEQEAEKLTAFIREKKTSWKNQMEPERCRIQ 212

Query: 184 WEFEQLYHSLKEHEYRLLARLEELDLAIYNSINGAITQFSCNISHLSSLIAQLEEKQQQP 243
            EF QL + L   E R L +LE+ +      I  A          L  LI+ LE + Q  
Sbjct: 213 TEFNQLRNILDRVEQRELKKLEQEEKKGLRIIEEAENDLVHQTQSLRELISDLERRCQGS 272

Query: 244 TRELLQDIGDTLSRAERIRIPEPWITPPDLQ 274
           T ELLQD+ D   R+E   + +P   P  L+
Sbjct: 273 TMELLQDVSDVTERSEFWTLRKPEALPTKLR 303


>gi|157426896 tripartite motif-containing 10 isoform 2 [Homo
           sapiens]
          Length = 395

 Score =  229 bits (583), Expect = 6e-60
 Identities = 135/397 (34%), Positives = 209/397 (52%), Gaps = 22/397 (5%)

Query: 1   MASGSVAECLQQETTCPVCLQYFAEPMMLDCGHNICCACLARCWGTA----ETNVSCPQC 56
           MAS +    L  E  CP+C     EP+ +DCGHN C ACL R         E + +CP C
Sbjct: 1   MASAASVTSLADEVNCPICQGTLREPVTIDCGHNFCRACLTRYCEIPGPDLEESPTCPLC 60

Query: 57  RETFPQRHMRPNRHLANVTQLVKQLRTERPSGPGGEMGVCEKHREPLKLYCEEDQMPICV 116
           +E F     RPN  LANV + +++L+     G G E  VC++H E +  +CE+D+M +CV
Sbjct: 61  KEPFRPGSFRPNWQLANVVENIERLQLVSTLGLGEE-DVCQEHGEKIYFFCEDDEMQLCV 119

Query: 117 VCDRSREHRGHSVLPLEEAVEGFKEQIQNQLDHLKRVKDLKKRRRAQGEQARAELLSLTQ 176
           VC  + EH  H++  LE+A   ++EQI   L  L++ ++  +  +++  +    LL+   
Sbjct: 120 VCREAGEHATHTMRFLEDAAAPYREQIHKCLKCLRKEREEIQEIQSRENKRMQVLLTQVS 179

Query: 177 MEREKIVWEFEQLYHSLKEHEYRLLARLEELDLAIYNSINGAITQFSCNISHLSSLIAQL 236
            +R++++ EF  L   L+E +  LLA+LE  D  I    +      +  I   S+LI +L
Sbjct: 180 TKRQQVISEFAHLRKFLEEQQSILLAQLESQDGDILRQRDEFDLLVAGEICRFSALIEEL 239

Query: 237 EEKQQQPTRELLQDIGDTLSRAERIRIPEPWITPPDLQEKIHIFAQKCLFLTESLKQFTE 296
           EEK ++P RELL DI  TL R E  +  +P    P+L ++I  F Q+ L L   +K F E
Sbjct: 240 EEKNERPARELLTDIRSTLIRCETRKCRKPVAVSPELGQRIRDFPQQALPLQREMKMFLE 299

Query: 297 KMQSDMEKIQELREAQLYSVDVTLDPDTAYPSLILSDNLRQVRYSYLQQDLPDNPERFNL 356
           K+  +++              ++LDP T++P L+LS++ ++ ++SY  Q+ PDNP+RF+ 
Sbjct: 300 KLCFELD---------YEPAHISLDPQTSHPKLLLSEDHQRAQFSYKWQNSPDNPQRFDR 350

Query: 357 FPCVLGSPCFIAGRHYWEVEVGDKAKWTIGVCEDSVC 393
             CVL       GRH W         W   V  DS C
Sbjct: 351 ATCVLAHTGITGGRHTW--------VWMARVPGDSGC 379


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.321    0.136    0.427 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 21,525,512
Number of Sequences: 37866
Number of extensions: 1041344
Number of successful extensions: 4768
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 241
Number of HSP's successfully gapped in prelim test: 256
Number of HSP's that attempted gapping in prelim test: 3680
Number of HSP's gapped (non-prelim): 867
length of query: 513
length of database: 18,247,518
effective HSP length: 107
effective length of query: 406
effective length of database: 14,195,856
effective search space: 5763517536
effective search space used: 5763517536
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.