Guide to the Human Genome
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Search of human proteins with 5729812

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|5729812 elongation factor RNA polymerase II [Homo sapiens]
         (621 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|5729812 elongation factor RNA polymerase II [Homo sapiens]        1252   0.0  
gi|155722987 elongation factor, RNA polymerase II, 2 [Homo sapiens]   553   e-157
gi|13376768 elongation factor RNA polymerase II-like 3 [Homo sap...   126   5e-29
gi|84370252 MARVEL domain containing 2 isoform 1 [Homo sapiens]        89   1e-17
gi|4505487 occludin [Homo sapiens]                                     84   4e-16
gi|13375756 occludin/ELL domain containing 1 [Homo sapiens]            60   6e-09
gi|4502951 collagen type III alpha 1 preproprotein [Homo sapiens]      51   3e-06
gi|163965366 nascent polypeptide-associated complex alpha subuni...    50   6e-06
gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi...    44   3e-04
gi|239754955 PREDICTED: similar to COL22A1 protein [Homo sapiens]      42   0.001
gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapi...    40   0.006
gi|162329583 cleavage and polyadenylation specific factor 6, 68 ...    40   0.008
gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapi...    40   0.008
gi|29725624 collagen, type XXIII, alpha 1 [Homo sapiens]               40   0.008
gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo ...    39   0.011
gi|118421085 leucine-rich repeat kinase 1 [Homo sapiens]               39   0.011
gi|169207799 PREDICTED: hypothetical protein [Homo sapiens]            39   0.014
gi|116284398 WAS/WASL interacting protein family, member 1 [Homo...    39   0.014
gi|38373695 WAS/WASL interacting protein family, member 1 [Homo ...    39   0.014
gi|45505151 nuclear factor I/C isoform 2 [Homo sapiens]                39   0.014
gi|93141049 collagen, type XII, alpha 1 short isoform precursor ...    39   0.014
gi|93141047 collagen, type XII, alpha 1 long isoform precursor [...    39   0.014
gi|122937496 WAS/WASL interacting protein family, member 3 [Homo...    39   0.014
gi|156142180 CXXC finger 1 (PHD domain) isoform 2 [Homo sapiens]       39   0.019
gi|147905592 coiled-coil domain containing 102B [Homo sapiens]         39   0.019
gi|148233522 coiled-coil domain containing 102B [Homo sapiens]         39   0.019
gi|223633935 hypothetical protein LOC254427 [Homo sapiens]             38   0.024
gi|116008152 alpha 1 type XV collagen precursor [Homo sapiens]         38   0.024
gi|239752594 PREDICTED: hypothetical protein, partial [Homo sapi...    38   0.024
gi|167614488 TBC1 domain family, member 10B [Homo sapiens]             38   0.024

>gi|5729812 elongation factor RNA polymerase II [Homo sapiens]
          Length = 621

 Score = 1252 bits (3240), Expect = 0.0
 Identities = 621/621 (100%), Positives = 621/621 (100%)

Query: 1   MAALKEDRSYGLSCGRVSDGSKVSVFHVKLTDSALRAFESYRARQDSVSLRPSIRFQGSQ 60
           MAALKEDRSYGLSCGRVSDGSKVSVFHVKLTDSALRAFESYRARQDSVSLRPSIRFQGSQ
Sbjct: 1   MAALKEDRSYGLSCGRVSDGSKVSVFHVKLTDSALRAFESYRARQDSVSLRPSIRFQGSQ 60

Query: 61  GHISIPQPDCPAEARTFSFYLSNIGRDNPQGSFDCIQQYVSSHGEVHLDCLGSIQDKITV 120
           GHISIPQPDCPAEARTFSFYLSNIGRDNPQGSFDCIQQYVSSHGEVHLDCLGSIQDKITV
Sbjct: 61  GHISIPQPDCPAEARTFSFYLSNIGRDNPQGSFDCIQQYVSSHGEVHLDCLGSIQDKITV 120

Query: 121 CATDDSYQKARQSMAQAEEETRSRSAIVIKAGGRYLGKKVQFRKPAPGATDAVPSRKRAT 180
           CATDDSYQKARQSMAQAEEETRSRSAIVIKAGGRYLGKKVQFRKPAPGATDAVPSRKRAT
Sbjct: 121 CATDDSYQKARQSMAQAEEETRSRSAIVIKAGGRYLGKKVQFRKPAPGATDAVPSRKRAT 180

Query: 181 PINLASAIRKSGASAVSGGSGVSQRPFRDRVLHLLALRPYRKAELLLRLQKDGLTQADKD 240
           PINLASAIRKSGASAVSGGSGVSQRPFRDRVLHLLALRPYRKAELLLRLQKDGLTQADKD
Sbjct: 181 PINLASAIRKSGASAVSGGSGVSQRPFRDRVLHLLALRPYRKAELLLRLQKDGLTQADKD 240

Query: 241 ALDGLLQQVANMSAKDGTCTLQDCMYKDVQKDWPGYSEGDQQLLKRVLVRKLCQPQSTGS 300
           ALDGLLQQVANMSAKDGTCTLQDCMYKDVQKDWPGYSEGDQQLLKRVLVRKLCQPQSTGS
Sbjct: 241 ALDGLLQQVANMSAKDGTCTLQDCMYKDVQKDWPGYSEGDQQLLKRVLVRKLCQPQSTGS 300

Query: 301 LLGDPAASSPPGERGRSASPPQKRLQPPDFIDPLANKKPRISHFTQRAQPAVNGKLGVPN 360
           LLGDPAASSPPGERGRSASPPQKRLQPPDFIDPLANKKPRISHFTQRAQPAVNGKLGVPN
Sbjct: 301 LLGDPAASSPPGERGRSASPPQKRLQPPDFIDPLANKKPRISHFTQRAQPAVNGKLGVPN 360

Query: 361 GREALLPTPGPPASTDTLSSSTHLPPRLEPPRAHDPLADVSNDLGHSGRDCEHGEAAAPA 420
           GREALLPTPGPPASTDTLSSSTHLPPRLEPPRAHDPLADVSNDLGHSGRDCEHGEAAAPA
Sbjct: 361 GREALLPTPGPPASTDTLSSSTHLPPRLEPPRAHDPLADVSNDLGHSGRDCEHGEAAAPA 420

Query: 421 PTVRLGLPLLTDCAQPSRPHGSPSRSKPKKKSKKHKDKERAAEDKPRAQLPDCAPATHAT 480
           PTVRLGLPLLTDCAQPSRPHGSPSRSKPKKKSKKHKDKERAAEDKPRAQLPDCAPATHAT
Sbjct: 421 PTVRLGLPLLTDCAQPSRPHGSPSRSKPKKKSKKHKDKERAAEDKPRAQLPDCAPATHAT 480

Query: 481 PGAPADTPGLNGTCSVSSVPTSTSETPDYLLKYAAISSSEQRQSYKNDFNAEYSEYRDLH 540
           PGAPADTPGLNGTCSVSSVPTSTSETPDYLLKYAAISSSEQRQSYKNDFNAEYSEYRDLH
Sbjct: 481 PGAPADTPGLNGTCSVSSVPTSTSETPDYLLKYAAISSSEQRQSYKNDFNAEYSEYRDLH 540

Query: 541 ARIERITRRFTQLDAQLRQLSQGSEEYETTRGQILQEYRKIKKTNTNYSQEKHRCEYLHS 600
           ARIERITRRFTQLDAQLRQLSQGSEEYETTRGQILQEYRKIKKTNTNYSQEKHRCEYLHS
Sbjct: 541 ARIERITRRFTQLDAQLRQLSQGSEEYETTRGQILQEYRKIKKTNTNYSQEKHRCEYLHS 600

Query: 601 KLAHIKRLIAEYDQRQLQAWP 621
           KLAHIKRLIAEYDQRQLQAWP
Sbjct: 601 KLAHIKRLIAEYDQRQLQAWP 621


>gi|155722987 elongation factor, RNA polymerase II, 2 [Homo sapiens]
          Length = 640

 Score =  553 bits (1426), Expect = e-157
 Identities = 306/642 (47%), Positives = 412/642 (64%), Gaps = 36/642 (5%)

Query: 4   LKEDRSYGLSCGRVSDGSKVSVFHVKLTDSALRAFESYRARQDSVSLRPSIRFQGSQGHI 63
           L+E++ YGLSCGR+   + ++V HVKLT++A+RA E+Y++ ++ +  RPSI+FQG  G +
Sbjct: 9   LREEQRYGLSCGRLGQDN-ITVLHVKLTETAIRALETYQSHKNLIPFRPSIQFQGLHGLV 67

Query: 64  SIPQPDCPAEARTFSFYLSNIGRDNPQGSFDCIQQYVSSHGEVHLDCLGSIQDKITVCAT 123
            IP+ D   E   F+FYLSN+G+DNPQGSFDCIQQ  SS G   L+CLG IQDKITVCAT
Sbjct: 68  KIPKNDPLNEVHNFNFYLSNVGKDNPQGSFDCIQQTFSSSGASQLNCLGFIQDKITVCAT 127

Query: 124 DDSYQKARQSMAQAEEETRSRSAIVIKAGGRYLGKKVQFRKPAPGATDAVPSRKRATPIN 183
           +DSYQ  R+ M QAEEE+R+RS  VIK GG Y+GK+VQ RK     +D VP RKR+TP+N
Sbjct: 128 NDSYQMTRERMTQAEEESRNRSTKVIKPGGPYVGKRVQIRKAPQAVSDTVPERKRSTPMN 187

Query: 184 LASAIRKSGASAVSGGSGVSQRPFRDRVLHLLALRPYRKAELLLRLQKDGLTQADKDALD 243
            A+ IRK+ +S     S +SQRP+RDRV+HLLAL+ Y+K ELL RLQKDG+ Q DK++L 
Sbjct: 188 PANTIRKTHSS-----STISQRPYRDRVIHLLALKAYKKPELLARLQKDGVNQKDKNSLG 242

Query: 244 GLLQQVANMSAKDGTCTLQDCMYKDVQKDWPGYSEGDQQLLKRVLVRKLCQPQSTGSLLG 303
            +LQQVAN+++KD + TL+D ++K++Q+DWPGYSE D++ L+ VL RKL   Q+     G
Sbjct: 243 AILQQVANLNSKDLSYTLKDYVFKELQRDWPGYSEIDRRSLESVLSRKLNPSQNAA---G 299

Query: 304 DPAASSPPGERGRSASPPQKRLQPPDFIDPLANKKPRISHFTQRAQPAVNGKLGVPNGRE 363
              + SP      + S PQKRL   +FIDPL NKK RISH T R  P +NG L  P   +
Sbjct: 300 TSRSESPVCSSRDAVSSPQKRLLDSEFIDPLMNKKARISHLTNRVPPTLNGHLN-PTSEK 358

Query: 364 ALLPTPGPPAS----TDTLSSSTHLPPRLEPPRAHDPLADVSNDLGHSGRDC-------- 411
           +    P PPA+    T     ST+LP    P   +      S   G   +D         
Sbjct: 359 SAAGLPLPPAAAAIPTPPPLPSTYLPISHPPQIVNSNSNSPSTPEGRGTQDLPVDSFSQN 418

Query: 412 ----EHGEAAAPAPTVRLGLP---LLTDCAQPSRPHGSPSRSKPKKKSKKHKDKERAAE- 463
               E  +    + T    LP   +L  C +P   + S S  K KKKSKKHK+K++  + 
Sbjct: 419 DSIYEDQQDKYTSRTSLETLPPGSVLLKCPKPMEENHSMSHKKSKKKSKKHKEKDQIKKH 478

Query: 464 -----DKPRAQLPDCAPATHATPGAPADTPGLNGTCSVSSVPTSTSETPDYLLKYAAISS 518
                ++    L            +P  + G+   C+ S  P S  E PDYL+KY AI S
Sbjct: 479 DIETIEEKEEDLKREEEIAKLNNSSPNSSGGVKEDCTASMEP-SAIELPDYLIKYIAIVS 537

Query: 519 SEQRQSYKNDFNAEYSEYRDLHARIERITRRFTQLDAQLRQLSQGSEEYETTRGQILQEY 578
            EQRQ+YK+DFNAEY EYR LHAR+E + RRF +LDAQ ++LS GS+EY+    ++LQEY
Sbjct: 538 YEQRQNYKDDFNAEYDEYRALHARMETVARRFIKLDAQRKRLSPGSKEYQNVHEEVLQEY 597

Query: 579 RKIKKTNTNYSQEKHRCEYLHSKLAHIKRLIAEYDQRQLQAW 620
           +KIK+++ NY +EK+RCEYLH+KLAHIKRLI E+DQ+Q ++W
Sbjct: 598 QKIKQSSPNYHEEKYRCEYLHNKLAHIKRLIGEFDQQQAESW 639


>gi|13376768 elongation factor RNA polymerase II-like 3 [Homo
           sapiens]
          Length = 397

 Score =  126 bits (317), Expect = 5e-29
 Identities = 71/203 (34%), Positives = 111/203 (54%), Gaps = 21/203 (10%)

Query: 434 AQPSRPHGSPSRSKPKKKSKKHKDKERAA-------EDKPRAQLPDCAPATHATPGAPAD 486
           +Q   P+  P ++ P   S+K  DK+R+        E+K    LP               
Sbjct: 191 SQTHVPNREPVQALPSSASRKRLDKKRSVPVATVELEEKRFRTLPLVPSPLQGLTNQDLQ 250

Query: 487 T------------PGLNGTCSVS--SVPTSTSETPDYLLKYAAISSSEQRQSYKNDFNAE 532
                        P L  + SV   S   S  + PDYLL+Y AI S+EQ+ +Y+ DF  +
Sbjct: 251 EGEDWEQEDEDMDPRLEHSSSVQEDSESPSPEDIPDYLLQYRAIHSAEQQHAYEQDFETD 310

Query: 533 YSEYRDLHARIERITRRFTQLDAQLRQLSQGSEEYETTRGQILQEYRKIKKTNTNYSQEK 592
           Y+EYR LHAR+   ++RF +L A+++++ +G+ EY+    +I+QEY+K +K   +Y +EK
Sbjct: 311 YAEYRILHARVGTASQRFIELGAEIKRVRRGTPEYKVLEDKIIQEYKKFRKQYPSYREEK 370

Query: 593 HRCEYLHSKLAHIKRLIAEYDQR 615
            RCEYLH KL+HIK LI E++++
Sbjct: 371 RRCEYLHQKLSHIKGLILEFEEK 393



 Score = 58.2 bits (139), Expect = 2e-08
 Identities = 34/109 (31%), Positives = 59/109 (54%), Gaps = 7/109 (6%)

Query: 18  SDGSKVSVFHVKLTDSALRAFESYRARQDSVSLRPSIRFQGSQGHISIPQPDCPAEARTF 77
           +  ++ S+  ++L D+ALRA +  + +Q    +RP I FQG +G++ +P P        F
Sbjct: 17  TQAARTSLLLLRLNDAALRALQECQRQQ----VRPVIAFQGHRGYLRLPGPGWSC---LF 69

Query: 78  SFYLSNIGRDNPQGSFDCIQQYVSSHGEVHLDCLGSIQDKITVCATDDS 126
           SF +S   ++   GS D + Q     G   L CLGS+++++ + A  DS
Sbjct: 70  SFIVSQCCQEGAGGSLDLVCQRFLRSGPNSLHCLGSLRERLIIWAAMDS 118


>gi|84370252 MARVEL domain containing 2 isoform 1 [Homo sapiens]
          Length = 558

 Score = 89.0 bits (219), Expect = 1e-17
 Identities = 43/111 (38%), Positives = 75/111 (67%), Gaps = 5/111 (4%)

Query: 507 PDYLLKYAAISSSEQRQSYKNDFNAEYSEYRDLHARIERITRRFTQLDAQLRQL---SQG 563
           PDY+ KY  I + ++R+ YK  F  ++SEY++L A ++ + R+F +LDA + +L   S+ 
Sbjct: 440 PDYVAKYPVIQTDDERERYKAVFQDQFSEYKELSAEVQAVLRKFDELDAVMSRLPHHSES 499

Query: 564 SEEYETTRGQILQEYRKIKKTNTNYSQEKHRCEYLHSKLAHIKRLIAEYDQ 614
            +E+E    +I +E++K KK +  + ++K RC+YL +KL+HIK+ I EYD+
Sbjct: 500 RQEHERI-SRIHEEFKK-KKNDPTFLEKKERCDYLKNKLSHIKQRIQEYDK 548


>gi|4505487 occludin [Homo sapiens]
          Length = 522

 Score = 84.0 bits (206), Expect = 4e-16
 Identities = 66/235 (28%), Positives = 105/235 (44%), Gaps = 27/235 (11%)

Query: 385 PPRLEPPRAHDPLADVSNDLGHSGRDC-EHGEAAAPAPTVRLGLPLLTDCAQPSRPHGSP 443
           PP     R   P+A  SN   +  R   E    + P P V   LPL +      +P  S 
Sbjct: 311 PPSDYVERVDSPMAYSSNGKVNDKRFYPESSYKSTPVPEVVQELPLTSPVDDFRQPRYS- 369

Query: 444 SRSKPKKKSKKHKDKERAAEDKPRAQLPDCAPATHATPGAPADTPGLNGTCSVSSVPTST 503
           S    +  SK+   K RA   K   Q  D     + T G   D                 
Sbjct: 370 SGGNFETPSKRAPAKGRAGRSKRTEQ--DHYETDYTTGGESCD----------------- 410

Query: 504 SETPDYLLKYAAISSSEQRQSYKNDFNAEYSEYRDLHARIERITRRFTQLDAQLRQLSQG 563
               D++ +Y  I+S +QRQ YK +F+    EY+ L + ++ I +  ++LD +L    + 
Sbjct: 411 ELEEDWIREYPPITSDQQRQLYKRNFDTGLQEYKSLQSELDEINKELSRLDKELDDYREE 470

Query: 564 SEEYETTRGQILQEYRKIK--KTNTNYSQEKHRCEYLHSKLAHIKRLIAEYDQRQ 616
           SEEY         EY ++K  K + +Y  +K+ C+ L SKL+HIK+++ +YD+++
Sbjct: 471 SEEYMAA----ADEYNRLKQVKGSADYKSKKNHCKQLKSKLSHIKKMVGDYDRQK 521


>gi|13375756 occludin/ELL domain containing 1 [Homo sapiens]
          Length = 264

 Score = 60.1 bits (144), Expect = 6e-09
 Identities = 63/270 (23%), Positives = 95/270 (35%), Gaps = 45/270 (16%)

Query: 367 PTPGPPASTDTLSSSTHLPPRLEPPRA-HD-------------------PLADVSNDLGH 406
           PT  P +   TL  +   PP   PPRA HD                   P+         
Sbjct: 10  PTADPGSELQTLGQAARRPP---PPRAGHDAPRRTRPSARKPLSCFSRRPMPTREPPKTR 66

Query: 407 SGRDCEHGEAAAPAPTVRLGLPLLTDCAQPSRPHGSPSRSKPKKKSKKHKDKERAAEDKP 466
             R   H     P P ++   P     + P  P       +P+    K K K+   ED+ 
Sbjct: 67  GSRGHLHTHPPGPGPPLQGLAPRGLKTSAPRPP------CQPQPGPHKAKTKKIVFEDEL 120

Query: 467 RAQ-LPDCAPATHATPGAPADTPGLNGTCSVSSVPTSTSETPDYLLKYAAISSSEQRQSY 525
            +Q L        A P      P                  PDY LKY  +SS  +R  Y
Sbjct: 121 LSQALLGAKKPIGAIPKGHKPRP---------------HPVPDYELKYPPVSSERERSRY 165

Query: 526 KNDFNAEYSEYRDLHARIERITRRFTQLDAQLRQLSQGSEEYETTRGQILQEYRKIKKTN 585
              F  +Y E+ +L   +     +  QL+A L  L     + E      +    ++K+ +
Sbjct: 166 VAVFQDQYGEFLELQHEVGCAQAKLRQLEALLSSLPPPQSQKEAQVAARVWREFEMKRMD 225

Query: 586 TNYSQEKHRCEYLHSKLAHIKRLIAEYDQR 615
             +  ++ RC YL  KL H+K  I ++D +
Sbjct: 226 PGFLDKQARCHYLKGKLRHLKTQIQKFDDQ 255


>gi|4502951 collagen type III alpha 1 preproprotein [Homo sapiens]
          Length = 1466

 Score = 51.2 bits (121), Expect = 3e-06
 Identities = 51/201 (25%), Positives = 65/201 (32%), Gaps = 25/201 (12%)

Query: 303 GDPAASSPPGERGRSASPPQKRLQPPDFIDPLANKKPRISHFTQRAQPAVNGKLGV--PN 360
           G P    PPG  G   SP     Q P      A              P   G +G   P 
Sbjct: 177 GPPGPPGPPGTSGHPGSPGSPGYQGPPGEPGQAGPS---------GPPGPPGAIGPSGPA 227

Query: 361 GREALLPTPGPPASTDTLSSSTHLPPRLEPPRAHDPLADVSNDLGHSGRDCEHGEAAAPA 420
           G++     PG P            PP ++ P        +    G  GR+ E GE  AP 
Sbjct: 228 GKDGESGRPGRPGERGLPG-----PPGIKGPAGIPGFPGMKGHRGFDGRNGEKGETGAPG 282

Query: 421 PTVRLGLPLLTDCAQPSRPHGSPSR----SKPKKKSKKHKDKERAAEDKPRAQLPDCAPA 476
                GLP       P  P G+P        P     +  D  R ++ +P    P     
Sbjct: 283 LKGENGLPGENGAPGPMGPRGAPGERGRPGLPGAAGARGNDGARGSDGQPGPPGPPGTAG 342

Query: 477 THATPGA-----PADTPGLNG 492
              +PGA     PA +PG NG
Sbjct: 343 FPGSPGAKGEVGPAGSPGSNG 363



 Score = 36.2 bits (82), Expect = 0.092
 Identities = 54/219 (24%), Positives = 64/219 (29%), Gaps = 24/219 (10%)

Query: 295  PQSTGSLLGDPAASSPPGERGRSASPPQK-RLQPPDFIDPLANKKPRISHFTQ-----RA 348
            P       G P  +  PG +G   +P +K    PP    P     P      Q     R 
Sbjct: 805  PPGPAGFPGAPGQNGEPGGKGERGAPGEKGEGGPPGVAGPPGGSGPAGPPGPQGVKGERG 864

Query: 349  QPAVNGKLGVPNGREALLP-----TPGPPASTDTLSSSTHLPPRLE-----PPRAHDPLA 398
             P   G  G P  R    P      PGPP  + +        P         P    P  
Sbjct: 865  SPGGPGAAGFPGARGLPGPPGSNGNPGPPGPSGSPGKDGPPGPAGNTGAPGSPGVSGPKG 924

Query: 399  DVSNDLGHSGRDCEHGEAAAPAPTVRLGLPLLTDCAQP---SRPHGSPSRSKPKKKSKKH 455
            D     G  G     G   AP P    G+      A P     P GSP     K +S K 
Sbjct: 925  DAGQP-GEKGSPGAQGPPGAPGPLGIAGITGARGLAGPPGMPGPRGSPGPQGVKGESGKP 983

Query: 456  KDKERAAEDKPRAQLPDCAPATHATPGAPA--DTPGLNG 492
                 + E  P    P   P    T G P     PG +G
Sbjct: 984  GANGLSGERGPPG--PQGLPGLAGTAGEPGRDGNPGSDG 1020



 Score = 35.0 bits (79), Expect = 0.21
 Identities = 45/193 (23%), Positives = 60/193 (31%), Gaps = 30/193 (15%)

Query: 303  GDPAASSPPGERGRSASPPQKRLQPPDFIDPLANKKPRISHFTQRAQPAVNGKLGVPNGR 362
            G P    PPG  G + +P    +  P         K       ++  P   G  G P   
Sbjct: 897  GSPGKDGPPGPAGNTGAPGSPGVSGP---------KGDAGQPGEKGSPGAQGPPGAPG-- 945

Query: 363  EALLPTPGPPASTDTLSSSTHL--PPRLEPPRAHDPLADVSNDLGHSGRDCEHGEAAAPA 420
                     P     ++ +  L  PP +  PR       V  + G  G +   GE   P 
Sbjct: 946  ---------PLGIAGITGARGLAGPPGMPGPRGSPGPQGVKGESGKPGANGLSGERGPPG 996

Query: 421  PTVRLGLPLLTDCA-QPSRPHGSPSRSKPKKKSKKHKDKERAAEDKPRAQLPDCAPATHA 479
            P    GLP L   A +P R     S   P +        +R     P A     AP  H 
Sbjct: 997  PQ---GLPGLAGTAGEPGRDGNPGSDGLPGRDGSPGGKGDRGENGSPGA---PGAPG-HP 1049

Query: 480  TPGAPADTPGLNG 492
             P  P    G +G
Sbjct: 1050 GPPGPVGPAGKSG 1062



 Score = 31.6 bits (70), Expect = 2.3
 Identities = 52/211 (24%), Positives = 63/211 (29%), Gaps = 32/211 (15%)

Query: 303 GDPAASSPPGERGRSASPPQKRLQ--PPDFIDPLANKKPRISHFTQRAQPAVNGKLGVPN 360
           G P  + P G++G +  P  + LQ  P     P  N KP         +P   G  G P 
Sbjct: 618 GPPGPTGPGGDKGDTGPPGPQGLQGLPGTGGPPGENGKP--------GEPGPKGDAGAPG 669

Query: 361 GREALLPTPGPPASTDTLSSSTHLPPRLEPPRAHDPLADVSNDLGHSGRDCEHGEAAAPA 420
                     P    D  +     PP L    A  P   +    G  G +   G A  P 
Sbjct: 670 ---------APGGKGDAGAPGERGPPGL----AGAP--GLRGGAGPPGPEGGKGAAGPPG 714

Query: 421 PTVRLGLPLLTDCAQPSRPHGSPSRSKPKKKSKKHKDKERAAEDKPRAQLPDCAPATHAT 480
           P    G P L          GSP     K +           +D PR       P   A 
Sbjct: 715 PPGAAGTPGLQGMPGERGGLGSPGPKGDKGEPGGPGADGVPGKDGPRGPTGPIGPPGPA- 773

Query: 481 PGAPAD-----TPGLNGTCSVSSVPTSTSET 506
            G P D      PGL G       P    ET
Sbjct: 774 -GQPGDKGEGGAPGLPGIAGPRGSPGERGET 803



 Score = 31.6 bits (70), Expect = 2.3
 Identities = 53/213 (24%), Positives = 66/213 (30%), Gaps = 42/213 (19%)

Query: 295 PQSTGSLLGDPAASSPPGERGRSASPPQKRLQPPDFIDPLA-NKKPRISHFTQRAQPAVN 353
           P     L G P    PPGE G+   P  K     D   P A   K       +R  P + 
Sbjct: 634 PPGPQGLQGLPGTGGPPGENGKPGEPGPK----GDAGAPGAPGGKGDAGAPGERGPPGLA 689

Query: 354 GKLGV--------PNGREALLPTPGPPASTDTLSSSTHLPPRLEPPRAHDPLADVSNDLG 405
           G  G+        P G +     PGPP +  T        P L+       +      LG
Sbjct: 690 GAPGLRGGAGPPGPEGGKGAAGPPGPPGAAGT--------PGLQ------GMPGERGGLG 735

Query: 406 HSGRDCEHGEAAAPAPTVRLGLPLLTDCAQPSRPHGSPS-RSKPKKKSKKHKDKERAAED 464
             G   + GE   P      G+P       P+ P G P    +P  K       E  A  
Sbjct: 736 SPGPKGDKGEPGGPGAD---GVPGKDGPRGPTGPIGPPGPAGQPGDKG------EGGAPG 786

Query: 465 KPRAQLPDCAPATHATPGAPA-----DTPGLNG 492
            P    P  +P      G P        PG NG
Sbjct: 787 LPGIAGPRGSPGERGETGPPGPAGFPGAPGQNG 819


>gi|163965366 nascent polypeptide-associated complex alpha subunit
            isoform a [Homo sapiens]
          Length = 2078

 Score = 50.1 bits (118), Expect = 6e-06
 Identities = 69/243 (28%), Positives = 91/243 (37%), Gaps = 41/243 (16%)

Query: 305  PAASSPPGERGRSASPPQKRLQPPDFIDPLANKKPRISHFTQRAQPAVNGKLGVPNGREA 364
            P A++PP  +G  A+PP K    P  + P + K            PA +   G P    A
Sbjct: 1266 PPAATPPSLKGGLATPPHKGAPNPAVVTPPSPK----------GGPATSPPKGAPTPPAA 1315

Query: 365  LLPTP-GPPASTDTLSSSTHLPPRLEPPRAHD----PLADVSNDLGHSGRDCEHGEAAAP 419
              P+P G P +     + T  PP + PP        P    S+  G +    + G     
Sbjct: 1316 TPPSPKGSPGTPPPKGAPT--PPAVTPPSPKGTPTLPATTPSSKGGPTTPSSKEGPTPPA 1373

Query: 420  APTVRLGLPLLTDCAQPSR------PHGSPSRS-----KPKKKSKKHKDKERAAEDK--- 465
            A     G P +T    P R      P G P+        PKK       +E AA      
Sbjct: 1374 ATPSHKGGPAMTP-PSPKRGPAIPSPKGDPTSPAVIPLSPKKAPATPVTREGAATPSKGD 1432

Query: 466  --PRAQLP---DCAPATHATPGAPADTPGLNGTCSVSSV-PTSTSETPDYLLKYAAISSS 519
              P A  P     APAT A  G PA TP   G  ++ +V P S  E P    K  A SSS
Sbjct: 1433 LTPPAVTPVSLKKAPATSAPKGGPA-TPSSKGDPTLPAVTPPSPKEPP--APKQVATSSS 1489

Query: 520  EQR 522
             ++
Sbjct: 1490 PKK 1492



 Score = 44.3 bits (103), Expect = 3e-04
 Identities = 58/220 (26%), Positives = 76/220 (34%), Gaps = 22/220 (10%)

Query: 305  PAASSPPGERGRSASPPQKRLQPPDFIDPLANK-KPRISHFTQRAQPAVNGKLGVPNGRE 363
            P A++PP  +G  A+P  K    P  + P + K  P  + F + A          P G  
Sbjct: 988  PPAATPPSPKGGPATPSPKGAPTPPAVTPPSPKGSPAATPFPKGASTPPAATPPSPKGSP 1047

Query: 364  ALLPTP--GPPASTDTLSSSTHLP--PRLE---PPRAHDPLADVSNDLGHSGRDCEHGEA 416
            A  P P   P     TL S    P  P L+    P A  P +        S +      A
Sbjct: 1048 AATPLPKGAPTTPAATLPSPKGGPATPSLKGAPTPPAATPPSPKGGPATPSPKGAPMPPA 1107

Query: 417  AAPAPTVRLGLPLLTDCAQPSRPHGSPSRSKPKKKSKKHKDKERAAEDKPRAQLPD---- 472
            A P P+ + GL        P+ P  +P    P  K        + A   P A  P     
Sbjct: 1108 ATP-PSPKGGLATPPHKGAPTTPAATP----PSPKGGLATPPPKGAPTTPAATPPSPKGG 1162

Query: 473  -CAPATHATPGAPADTP----GLNGTCSVSSVPTSTSETP 507
               P     P  PA TP    G   T S    PT+ + TP
Sbjct: 1163 LATPPPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATP 1202



 Score = 41.2 bits (95), Expect = 0.003
 Identities = 55/213 (25%), Positives = 72/213 (33%), Gaps = 31/213 (14%)

Query: 305  PAASSPPGERGRSASPPQKRLQPPDFIDPLANKKPRISHFTQRAQPAVNGKLGVPNGREA 364
            P A++PP  +G  A+P  K    P    P + K            PA     G P    A
Sbjct: 942  PPAATPPSPKGGPATPSPKWAPTPPAATPPSPK----------GGPATPSPKGAPTPPAA 991

Query: 365  LLPTP-GPPASTDTLSSSTHLPPRLEPPRAHDPLADVSNDLGHSGRDCEHGEAAAPAPTV 423
              P+P G PA+     + T  PP + PP      A      G S        A  P+P  
Sbjct: 992  TPPSPKGGPATPSPKGAPT--PPAVTPPSPKGSPAATPFPKGASTPPA----ATPPSPK- 1044

Query: 424  RLGLPLLTDCAQPSRPHGSPSRSKPKKKSKKHKDKERAAEDKPRAQLPD-----CAPATH 478
              G P  T    P     +P+ + P  K        + A   P A  P        P+  
Sbjct: 1045 --GSPAATPL--PKGAPTTPAATLPSPKGGPATPSLKGAPTPPAATPPSPKGGPATPSPK 1100

Query: 479  ATPGAPADTP----GLNGTCSVSSVPTSTSETP 507
              P  PA TP    G   T      PT+ + TP
Sbjct: 1101 GAPMPPAATPPSPKGGLATPPHKGAPTTPAATP 1133



 Score = 40.0 bits (92), Expect = 0.006
 Identities = 55/213 (25%), Positives = 69/213 (32%), Gaps = 31/213 (14%)

Query: 305  PAASSPPGERGRSASPPQKRLQPPDFIDPLANKKPRISHFTQRAQPAVNGKLGVPNGREA 364
            P A++PP  +G  A+P  K    P    P + K            PA     G P     
Sbjct: 965  PPAATPPSPKGGPATPSPKGAPTPPAATPPSPK----------GGPATPSPKGAPTPPAV 1014

Query: 365  LLPTP-GPPASTDTLSSSTHLPPRLEPPR-----AHDPLADVSNDLGHSGRDCEHGEAAA 418
              P+P G PA+T         PP   PP      A  PL   +     +      G  A 
Sbjct: 1015 TPPSPKGSPAAT-PFPKGASTPPAATPPSPKGSPAATPLPKGAPTTPAATLPSPKGGPAT 1073

Query: 419  PAPTVRLGLPLLTDCAQPSRPHGSPSRSKPKKKSKKHKDKERAAEDKPRAQLPDCAPATH 478
            P+     G P     A P  P G P+   PK           A    P+  L    P   
Sbjct: 1074 PS---LKGAP-TPPAATPPSPKGGPATPSPKGAPM----PPAATPPSPKGGL--ATPPHK 1123

Query: 479  ATPGAPADTP----GLNGTCSVSSVPTSTSETP 507
              P  PA TP    G   T      PT+ + TP
Sbjct: 1124 GAPTTPAATPPSPKGGLATPPPKGAPTTPAATP 1156



 Score = 38.9 bits (89), Expect = 0.014
 Identities = 63/247 (25%), Positives = 88/247 (35%), Gaps = 22/247 (8%)

Query: 295  PQSTGSLLGDPAASSPPGERGRSASPPQKRLQPPDFIDPLANKKPRISHFTQR-AQPAVN 353
            P +T S  G PA + P  +RG +   P+     P  I PL+ KK   +  T+  A     
Sbjct: 1372 PAATPSHKGGPAMTPPSPKRGPAIPSPKGDPTSPAVI-PLSPKKAPATPVTREGAATPSK 1430

Query: 354  GKLGVPNGREALL---PTPGPPASTDTLSSSTHLP--PRLEPPRAHDPLADVSNDLGHSG 408
            G L  P      L   P    P       SS   P  P + PP   +P A        S 
Sbjct: 1431 GDLTPPAVTPVSLKKAPATSAPKGGPATPSSKGDPTLPAVTPPSPKEPPAPKQVATSSSP 1490

Query: 409  RDCEHGEAAAPAPTVRLGLPLLTDCAQPSRPHGSPSRSKPKKKSKKHKDKERAAEDKPR- 467
            +       A PAP     LP +   +    P    SR  P   +     K+  A   P+ 
Sbjct: 1491 KKA----PATPAPMGAPTLPAVIPSSPKEVPATPSSRRDPIAPTATLLSKKTPATLAPKE 1546

Query: 468  AQLPDC--APATHATPG--APADTPGLNGTCSVSSVPTSTSET------PDYLLKYAAIS 517
            A +P     P+   TP    P + P    +   SS P  T  T      P  LL   A++
Sbjct: 1547 ALIPPAMTVPSPKKTPAIPTPKEAPATPSSKEASSPPAVTPSTYKGAPSPKELLIPPAVT 1606

Query: 518  SSEQRQS 524
            S   +++
Sbjct: 1607 SPSPKEA 1613


>gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo
           sapiens]
          Length = 1124

 Score = 44.3 bits (103), Expect = 3e-04
 Identities = 64/251 (25%), Positives = 85/251 (33%), Gaps = 44/251 (17%)

Query: 296 QSTGSLLGDPAASSPPGERGRSASPPQKRLQPPDFIDP-----------LANKKPRISHF 344
           +S G+   +PA+  P   RG  A PP K   P     P           L  K  RIS  
Sbjct: 81  RSAGTSSRNPASRPPASGRGERA-PPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRIS-- 137

Query: 345 TQRAQPAVNGKLGVPNGREALL---------PTPGPPAS-----TDTLSSSTHLP---PR 387
               +    GK      R AL          PTPG P+      +    +   LP   P 
Sbjct: 138 --AEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPS 195

Query: 388 LEP-PRAHDPLADVSNDLGHSGRDCEHGEAAAPAPTVRLGLPLLTDCAQPSRPHGSPSRS 446
             P P    P   VS+   HS  +        P+    L  P     +  + P  SP+RS
Sbjct: 196 ARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARS 255

Query: 447 KPKKKS--------KKHKDKERAAEDKPRAQLP--DCAPATHATPGAPADTPGLNGTCSV 496
            P  +          + K K   A   P+   P  D APA      +P  TP  +GT + 
Sbjct: 256 GPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSGTKAR 315

Query: 497 SSVPTSTSETP 507
              P   + TP
Sbjct: 316 PVPPPDNAATP 326



 Score = 38.5 bits (88), Expect = 0.019
 Identities = 62/232 (26%), Positives = 76/232 (32%), Gaps = 41/232 (17%)

Query: 295 PQSTGSLLGDPAASSPPGERGRSASPPQKRLQPPDFIDPLA-------------NKKPRI 341
           P      L  P   +PP      ASPP   L  P    P A                P  
Sbjct: 618 PPQAPPXLALPPLQAPPSP---PASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQ 674

Query: 342 SHFTQRAQPAVNGKLGVPNGREALLPTP------GPPASTDTLSSSTHLPPRLEPPRAHD 395
           + F+  A P V+     P+     L  P       PPAS     S+T  PP+  PP A  
Sbjct: 675 APFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATP-PPQAPPPLAAP 733

Query: 396 PLADVSNDLGHSGRDCEHGEAAAPAPTVRLGLPLLTDCAQPSRPHGSPSRSKPKKKSKKH 455
           PL    +             +A P P V    PLL   A P +   SP  S P       
Sbjct: 734 PLQVPPSPPASP----PMSPSATPPPRVP---PLL--AAPPLQVPPSPPASLPMSP---- 780

Query: 456 KDKERAAEDKPRAQLPDCAPATHATPGAPADTPGLNGTCSVSSVPTSTSETP 507
                 A+  P+A      P   A P  PA  PG       +S+P S   TP
Sbjct: 781 -----LAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATP 827



 Score = 33.9 bits (76), Expect = 0.46
 Identities = 61/243 (25%), Positives = 75/243 (30%), Gaps = 56/243 (23%)

Query: 295 PQSTGSLLGDPAASSPPGERGRSASPPQKRLQPPDF---------------IDPLANKKP 339
           P    SL   P A  PP      A+PP + L  P                 + PLA   P
Sbjct: 770 PSPPASLPMSPLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPP 829

Query: 340 RISHFTQRA------QPAVNGKLGVPNGREALLPTPGPPASTDTLSSSTHLPPRLEPPRA 393
           +               P  +  L  P       PTPGP  S      +  L P   PP +
Sbjct: 830 QAPPVLAAPLLQVPPSPPASPTLQAPRRP----PTPGPDTSVSGPRLTLALAPGPPPPPS 885

Query: 394 HDPLADVSN-DLGHSGRDCEHGEAAAPAPTVRLGLPLLTDCAQPSRPHGSPSRSKPKKKS 452
             P + +S  DL        H  +A   P    G          S P G  + S P    
Sbjct: 886 RSPSSTLSGPDL------AGHSSSATSTPEELRG--------YDSGPEGGAAASPP---- 927

Query: 453 KKHKDKERAAEDKPRAQLPDCAP--ATHATPGAPADTP------GLNGTCSVSSVPTSTS 504
               D E AA   P A     AP  A    PGAP   P        +G C++       S
Sbjct: 928 ---PDAELAA-CHPAAWSRGPAPPLAFRGAPGAPLPWPPATGPGSADGLCTIYETEGPES 983

Query: 505 ETP 507
            TP
Sbjct: 984 ATP 986



 Score = 30.0 bits (66), Expect = 6.6
 Identities = 54/231 (23%), Positives = 82/231 (35%), Gaps = 32/231 (13%)

Query: 295 PQSTGSLLGDPAASSPPGER---GRSASPPQKRLQPPDFIDPLANKKPRISHFTQRAQPA 351
           P +T   L  P+ S+PP  +      A+PP +   PP    P     P +    Q   P 
Sbjct: 336 PLATPLPLAPPSPSAPPSLQTLPSPPATPPSQA--PPSMTTPPMQAPPSL----QTIPP- 388

Query: 352 VNGKLGVPNGREA-LLPTPGPPASTDTLSSSTHL-PPRLEPPRAHDPLADVSNDLGHSGR 409
               + VP+   +  L  P  P +  +L ++T L  P L+   A      +S     +  
Sbjct: 389 ----IQVPHSLTSPSLQAPPSPLALSSLQATTSLGSPTLQ---ATHSFLTMSPRQTQASL 441

Query: 410 DCEHGEAAAPAPTVRLGLPLLTDCAQPSRPHGSPSRSKPKKKSKKH--KDKERAAEDKPR 467
                 A+ P  +  L  PL    + P +   SP+ S        H  +     A   P+
Sbjct: 442 TSPSRPASTPPDSPPLQAPLSLPASPPLQTSLSPAVSPLSSPLTIHPLQALSSLASHSPQ 501

Query: 468 AQLPDC-----------APATHATPGAPADTPGLNGTCSVSSVPTSTSETP 507
           A L              AP +  TP A   TP L    S++  P  T+  P
Sbjct: 502 APLSSLIMPPLETQSSLAPPSLQTPPASLTTPPLENLPSLAPPPLQTASAP 552


>gi|239754955 PREDICTED: similar to COL22A1 protein [Homo sapiens]
          Length = 1073

 Score = 42.4 bits (98), Expect = 0.001
 Identities = 58/253 (22%), Positives = 84/253 (33%), Gaps = 47/253 (18%)

Query: 277 SEGDQQLLKRVLVRKLCQPQSTG-----SLLGDPAASSPPGERG----RSASPPQKRLQP 327
           S GD  LL + +    C P   G        GD      PG  G    +  + P     P
Sbjct: 549 SPGDINLLAKDVCND-CPPGPPGLPGLPGFKGDKGVPGKPGREGTEGKKGEAGPPGLPGP 607

Query: 328 PDFIDPLANKKPR-----ISHFTQRAQPAVNGKLGVPNGREALLPTPGPPASTDTLSSST 382
           P    P  ++  R     +     +  P V G +G P         PGPP +     ++ 
Sbjct: 608 PGIAGPQGSQGERGADGEVGQKGDQGHPGVPGFMGPPGN-------PGPPGADGIAGAAG 660

Query: 383 HLPPRLE-------PPRAHDP--LADVSNDLGHSGRDCEHGEAAAPAPTVRLGLP----- 428
             PP ++       PP    P  L  +  + G  GRD + G    P      GLP     
Sbjct: 661 --PPGIQGSPGKEGPPGPQGPSGLPGIPGEEGKEGRDGKPGPPGEPGKAGEPGLPGPEGA 718

Query: 429 --------LLTDCAQPSRPHGSPSRSKPKKKSKKHKDKERAAEDKPRAQLPDCAPATHAT 480
                      D   P     S +   P ++    KD +         Q P   P  + +
Sbjct: 719 RGPPGFKGHTGDSGAPGPRGESGAMGLPGQEGLPGKDGDTGPTGPQGPQGPRGPPGKNGS 778

Query: 481 PGAPADTPGLNGT 493
           PG+P + PG +GT
Sbjct: 779 PGSPGE-PGPSGT 790



 Score = 29.6 bits (65), Expect = 8.6
 Identities = 25/79 (31%), Positives = 32/79 (40%), Gaps = 9/79 (11%)

Query: 295 PQSTGSLLGDPAASSPPGERGRSASPPQKRLQPPDFIDPLANKKPRISHFT-QRAQPAVN 353
           PQ      G   +   PGE G S +P QK  +         N  P +  F   R  P   
Sbjct: 766 PQGPRGPPGKNGSPGSPGEPGPSGTPGQKGSKG-------ENGSPGLPGFLGPRGPPGEP 818

Query: 354 GKLGVPNGREALLPTPGPP 372
           G+ GVP G+E +   PG P
Sbjct: 819 GEKGVP-GKEGVPGKPGEP 836


>gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo
           sapiens]
          Length = 855

 Score = 40.0 bits (92), Expect = 0.006
 Identities = 61/245 (24%), Positives = 81/245 (33%), Gaps = 44/245 (17%)

Query: 296 QSTGSLLGDPAASSPPGERGRSASPPQKRLQPPDFID-----------PLANKKPRISHF 344
           +S G+   +PA+  P   RG  A PP K   P                PL  K  RIS  
Sbjct: 81  RSAGTSSRNPASRPPASGRGERA-PPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRIS-- 137

Query: 345 TQRAQPAVNGKLGVPNGREALL---------PTPGPPA-----STDTLSSSTHLP---PR 387
               +    GK      R AL          PTPG P+      +    +   LP   P 
Sbjct: 138 --AEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPS 195

Query: 388 LEP-PRAHDPLADVSNDLGHSGRDCEHGEAAAPAPTVRLGLPLLTDCAQPSRPHGSPSRS 446
             P P    P   VS+   HS  +        P+    L  P     +  + P  SP+RS
Sbjct: 196 ARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARS 255

Query: 447 KPKKKS--------KKHKDKERAAEDKPRAQLP--DCAPATHATPGAPADTPGLNGTCSV 496
            P  +          + K K   A   P+   P  D APA      +P  TP  +     
Sbjct: 256 GPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAALQS 315

Query: 497 SSVPT 501
            + PT
Sbjct: 316 QAPPT 320



 Score = 34.3 bits (77), Expect = 0.35
 Identities = 58/228 (25%), Positives = 80/228 (35%), Gaps = 33/228 (14%)

Query: 305 PAASSPPGERGRSA------SPPQKRLQP---PDFIDPLANKKPRISHFTQR-----AQP 350
           PA  S P  +G  A      +PP+K   P   P    PLA   P  +  +Q      A P
Sbjct: 266 PAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAALQSQAPPTLPATP 325

Query: 351 ---AVNGKLGVPNGREALLPTPGPPASTDTLSSSTHLPPRLEPPRAHDPLADVSNDLGHS 407
              ++  +L  P       P+P  P S  TL S    PP   P +A   L   +    HS
Sbjct: 326 HSSSLTCQLATP--LPLAPPSPSAPPSLQTLPS----PPATPPSQATTSLGSPTLQATHS 379

Query: 408 GRDCEH-GEAAAPAPTV--RLGLPLL-----TDCAQPSRPHGSPSRSKPKKKSKKHKDKE 459
                     A P P     L LP L        + P  P  +PS   P   +       
Sbjct: 380 FLPSPPLSPLATPPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAP 439

Query: 460 RAAEDKPRAQLPDCAPATHATPGAPADTPGLNGTCSVSSVPTSTSETP 507
            +    P  Q P   PA  + P +P+ TP      S+++ P     +P
Sbjct: 440 FSPPPSPPVQAPFSPPA--SPPVSPSATPPSQAPPSLAAPPLQVPPSP 485



 Score = 33.5 bits (75), Expect = 0.60
 Identities = 67/283 (23%), Positives = 90/283 (31%), Gaps = 77/283 (27%)

Query: 295 PQSTGSLLGDPAASSPPGERGRSASPPQKRLQPPDFIDPLANKKPRISH----------- 343
           P +T      PA + PP +     +PP     PP  + PLA   P+  +           
Sbjct: 388 PLATPPPQAPPALALPPLQ-----APPSPPASPP--LSPLATPSPQAPNALAVHLLQAPF 440

Query: 344 -----------FTQRAQPAVNGKLGVPNGREALLPTP------GPPASTDTLSSSTHLPP 386
                      F+  A P V+     P+     L  P       PPAS     S+T  PP
Sbjct: 441 SPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATP-PP 499

Query: 387 RLEPPRAHDPLADVSNDLGHSGRDCEHGEAAAPAPTVRLGLPLLTDCAQPSRPHG----- 441
           +  PP A  PL                 + A P P     L      A PS P       
Sbjct: 500 QAPPPLAAPPL-----------------QLAKPPPQAPPALATPPLQALPSPPASFPGQA 542

Query: 442 --SPSRSKPKKKSKKHKDKERAAEDKPRAQLPDCAPATHA--------TPGAPADTPGLN 491
             SPS S P         +       P  Q+P   PA+          TPG      G  
Sbjct: 543 PFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPR 602

Query: 492 GTCSV--------SSVPTSTSETPDYL-LKYAAISSSEQRQSY 525
            T ++        S  P+ST   PD      +A S+ E+ + Y
Sbjct: 603 LTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGY 645


>gi|162329583 cleavage and polyadenylation specific factor 6, 68 kD
           subunit [Homo sapiens]
          Length = 551

 Score = 39.7 bits (91), Expect = 0.008
 Identities = 55/214 (25%), Positives = 70/214 (32%), Gaps = 33/214 (15%)

Query: 310 PPGERGRSASPPQKRLQPPDFIDP--LANKKPRISHFTQRAQPAVNGKLG-VPNGREALL 366
           PPG  G    PP  ++ PP    P    ++ P    F    QP     LG +P G    +
Sbjct: 243 PPGPPGPPGPPPPGQVLPPPLAGPPNRGDRPPPPVLFP--GQPFGQPPLGPLPPGPPPPV 300

Query: 367 PTPGPPASTDTLSSSTHLPPRLEPPRAHDPLADVSNDLGHSGRDCEHGEAAAPAPTVRLG 426
           P  GPP            PP   PPR   PL                    AP P     
Sbjct: 301 PGYGPPPGPPPPQQGPPPPPGPFPPRPPGPLGPPL--------------TLAPPP----H 342

Query: 427 LPLLTDCAQPSRPHGSPSRSKPKKKS-KKHKDKERAAEDKPRAQLPDCAPATHATPGAPA 485
           LP     A P  PH +P+   P   S     D        P  + P      +  PG   
Sbjct: 343 LPGPPPGAPPPAPHVNPAFFPPPTNSGMPTSDSRGPPPTDPYGRPPPYDRGDYGPPGREM 402

Query: 486 DTPGLNGTCSVSSVPTSTSETPDYLLKYAAISSS 519
           DT         +  P S +E  + + +  AISSS
Sbjct: 403 DT---------ARTPLSEAEFEEIMNRNRAISSS 427



 Score = 30.8 bits (68), Expect = 3.9
 Identities = 43/202 (21%), Positives = 62/202 (30%), Gaps = 47/202 (23%)

Query: 305 PAASSPPGERGRSASPPQKRLQPPDFIDPLANKKPRISHFTQRAQPAVNGKLGVPNGREA 364
           P    PPG  G    PP     PP    P     P   H      P      G+P     
Sbjct: 322 PFPPRPPGPLG----PPLTLAPPPHLPGPPPGAPPPAPHVNPAFFPPPTNS-GMPTSDSR 376

Query: 365 LLPTPGPPASTDTLSSSTHLPPRLEPPRAHDPLADV-------------SNDLGHSGRDC 411
             P   P           + PP  E   A  PL++              S+ +  +  D 
Sbjct: 377 GPPPTDPYGRPPPYDRGDYGPPGREMDTARTPLSEAEFEEIMNRNRAISSSAISRAVSDA 436

Query: 412 EHGEAAAPAPTVRLGLPL------------------LTDCAQ--PSRPHGSPSR------ 445
             G+  +   T+   + L                  L DC     S+ +GS SR      
Sbjct: 437 SAGDYGSAIETLVTAISLIKQSKVSADDRCKVLISSLQDCLHGIESKSYGSGSRRERSRE 496

Query: 446 ---SKPKKKSKKHKDKERAAED 464
              S+ ++KS++HK + R   D
Sbjct: 497 RDHSRSREKSRRHKSRSRDRHD 518


>gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo
           sapiens]
          Length = 816

 Score = 39.7 bits (91), Expect = 0.008
 Identities = 56/227 (24%), Positives = 78/227 (34%), Gaps = 31/227 (13%)

Query: 297 STGSLLGDPAASSP-----PGERGRSASPPQKRLQ---PPDFIDPLANKKPRISHFTQRA 348
           S+ + L  PA S P     P      + P  K LQ   PP    P  +  P +       
Sbjct: 235 SSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALG------ 288

Query: 349 QPAVNGKLGVPNGREALLPTPGPPASTDTLSSSTHLPPRLEPPRAHDPLADVSNDLGHSG 408
            P  +  L  P+   +  P+P  P S  TL S    PP   P +A   L   +    HS 
Sbjct: 289 -PLSSSPLATPS--PSAPPSPSAPPSLQTLPS----PPATPPSQATTSLGSPTLQATHSF 341

Query: 409 RDCEH-GEAAAPAPTV--RLGLPLL-----TDCAQPSRPHGSPSRSKPKKKSKKHKDKER 460
                    A P P     L LP L        + P  P  +PS   P   +        
Sbjct: 342 LPSPPLSPLATPPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPF 401

Query: 461 AAEDKPRAQLPDCAPATHATPGAPADTPGLNGTCSVSSVPTSTSETP 507
           +    P  Q P   PA  + P +P+ TP      S+++ P     +P
Sbjct: 402 SPPPSPPVQAPFSPPA--SPPVSPSATPPSQAPPSLAAPPLQVPPSP 446



 Score = 33.5 bits (75), Expect = 0.60
 Identities = 67/283 (23%), Positives = 90/283 (31%), Gaps = 77/283 (27%)

Query: 295 PQSTGSLLGDPAASSPPGERGRSASPPQKRLQPPDFIDPLANKKPRISH----------- 343
           P +T      PA + PP +     +PP     PP  + PLA   P+  +           
Sbjct: 349 PLATPPPQAPPALALPPLQ-----APPSPPASPP--LSPLATPSPQAPNALAVHLLQAPF 401

Query: 344 -----------FTQRAQPAVNGKLGVPNGREALLPTP------GPPASTDTLSSSTHLPP 386
                      F+  A P V+     P+     L  P       PPAS     S+T  PP
Sbjct: 402 SPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATP-PP 460

Query: 387 RLEPPRAHDPLADVSNDLGHSGRDCEHGEAAAPAPTVRLGLPLLTDCAQPSRPHG----- 441
           +  PP A  PL                 + A P P     L      A PS P       
Sbjct: 461 QAPPPLAAPPL-----------------QLAKPPPQAPPALATPPLQALPSPPASFPGQA 503

Query: 442 --SPSRSKPKKKSKKHKDKERAAEDKPRAQLPDCAPATHA--------TPGAPADTPGLN 491
             SPS S P         +       P  Q+P   PA+          TPG      G  
Sbjct: 504 PFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPR 563

Query: 492 GTCSV--------SSVPTSTSETPDYL-LKYAAISSSEQRQSY 525
            T ++        S  P+ST   PD      +A S+ E+ + Y
Sbjct: 564 LTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGY 606


>gi|29725624 collagen, type XXIII, alpha 1 [Homo sapiens]
          Length = 540

 Score = 39.7 bits (91), Expect = 0.008
 Identities = 51/193 (26%), Positives = 62/193 (32%), Gaps = 27/193 (13%)

Query: 303 GDPAASSPPGERGRSASPPQKRLQPPDFIDPLANKKPRISHFTQRAQPAVNGKLGVPNGR 362
           GDP    PPG+ GR   P    L     +     +K     F  R     +G  G P   
Sbjct: 133 GDPG---PPGQSGRDGYPGPLGLDGKPGLPGPKGEKGAPGDFGPRGDQGQDGAAGPPG-- 187

Query: 363 EALLPTPGPPASTDTLSSSTHLPPRLEPPRAHDPLADVSNDLGHSGRDCEHGEAAAPAPT 422
                 PGPP +      +    PR     A  P    +   G  G+D E G    P P 
Sbjct: 188 -----PPGPPGARGPPGDTGKDGPR----GAQGP----AGPKGEPGQDGEMGPKGPPGPK 234

Query: 423 VRLGLP-LLTDCAQPSRPHGSPSRSKPKKKSKKHKDKERAAEDKPRAQLPDCAPATHATP 481
              G+P    D   PS+P        P  K +      R       A  P   P    T 
Sbjct: 235 GEPGVPGKKGDDGTPSQP------GPPGPKGEPGSMGPRGENGVDGAPGPKGEPGHRGTD 288

Query: 482 GA--PADTPGLNG 492
           GA  P   PGL G
Sbjct: 289 GAAGPRGAPGLKG 301


>gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo
            sapiens]
          Length = 5537

 Score = 39.3 bits (90), Expect = 0.011
 Identities = 55/228 (24%), Positives = 81/228 (35%), Gaps = 36/228 (15%)

Query: 297  STGSLLGDPAASSPPGERGRSASPPQKRLQP-------PDFIDPLANKKPRISHFTQRAQ 349
            S   LLG+PA S P GE   S  P +  L P       P  + P     P     T  A 
Sbjct: 890  SLSPLLGEPALSEP-GEPPLSPLPEELPLSPSGEPSLSPQLMPPDPLPPPLSPIITAAAP 948

Query: 350  PAVN--GKLGVPNGREA-----------LLPTPGPPASTDTLSSSTHLPPRLEPPRAHDP 396
            PA++  G+L  P G +            +L TP  P      +    +PP + PP    P
Sbjct: 949  PALSPLGELEYPFGAKGDSDPESPLAAPILETPISPPPEANCTDPEPVPPMILPPSPGSP 1008

Query: 397  LADVSNDL-----GHSGRDCEHGEAAAPAPTVRLGLPLLTDCAQPSRPHGSPSRSKPKKK 451
            +   S  L            +H      +P         + C+ P+ P   PS   P  K
Sbjct: 1009 VGPASPILMEPLPPQCSPLLQHSLVPQNSPP--------SQCSPPALPLSVPSPLSPIGK 1060

Query: 452  SKKHKDKERAAE-DKPRAQLPDCAPATHATPGAPADTPGLNGTCSVSS 498
                 D+    E +  +   P+C PA   +  +P  +P  + +C   S
Sbjct: 1061 VVGVSDEAELHEMETEKVSEPEC-PALEPSATSPLPSPMGDLSCPAPS 1107



 Score = 38.1 bits (87), Expect = 0.024
 Identities = 37/141 (26%), Positives = 53/141 (37%), Gaps = 18/141 (12%)

Query: 305 PAASSPPGERGRSASPPQKRLQPP---DFIDPLANKKPRISHFTQRAQPAVNGKLGVPNG 361
           P    PP E G+  +P +  L PP     + PL   +P +S   +  +P ++     P  
Sbjct: 862 PRPEKPPEEPGQCPAPEELPLFPPPGEPSLSPLLG-EPALS---EPGEPPLS-----PLP 912

Query: 362 REALLPTPGPPASTDTLSSSTHLPPRLEP------PRAHDPLADVSNDLGHSGRDCEHGE 415
            E  L   G P+ +  L     LPP L P      P A  PL ++    G  G       
Sbjct: 913 EELPLSPSGEPSLSPQLMPPDPLPPPLSPIITAAAPPALSPLGELEYPFGAKGDSDPESP 972

Query: 416 AAAPAPTVRLGLPLLTDCAQP 436
            AAP     +  P   +C  P
Sbjct: 973 LAAPILETPISPPPEANCTDP 993



 Score = 35.8 bits (81), Expect = 0.12
 Identities = 45/167 (26%), Positives = 56/167 (33%), Gaps = 35/167 (20%)

Query: 288 LVRKLCQPQSTGSLLGDPAAS--SPPGERGRSASPPQKRLQPPDFIDPLANKKPRISHFT 345
           +V +L  P     L   P  S  SPP E  R + PP+     P   D  A+  P      
Sbjct: 658 VVSRLSPPPEESPLSPPPEESPTSPPPEASRLSPPPEDSPTSPPPEDSPASPPPE----- 712

Query: 346 QRAQPAVNGKLGVPNGREALLPTPGPPASTDTLSSSTHLPPRLE----PPRAHDPLADVS 401
                  +  + +P     LLP P  P      S   HL PR E     PR  +P     
Sbjct: 713 -------DSLMSLPLEESPLLPLPEEPQLCPR-SEGPHLSPRPEEPHLSPRPEEPHLSPQ 764

Query: 402 NDLGHSGRDCEHGEAAAPAPTVRLGLPLLTDCAQPSRPHGSPSRSKP 448
            +  H           +P P      P L  CA P  PH SP    P
Sbjct: 765 AEEPH----------LSPQPEE----PCL--CAVPEEPHLSPQAEGP 795



 Score = 32.3 bits (72), Expect = 1.3
 Identities = 56/203 (27%), Positives = 73/203 (35%), Gaps = 23/203 (11%)

Query: 301 LLGDPAAS--SPPGERGRSASPPQ-KRLQPPDFIDPLANKKPRISHFTQRAQPAVNGKLG 357
           LL  P  S  SPP E   ++ PP+  RL PP    P A+  P   H    ++P     L 
Sbjct: 440 LLPPPEESPLSPPPEESPTSPPPEASRLSPPPEELP-ASPLPEALHL---SRPLEESPLS 495

Query: 358 VPNGREALLP----TPGPPASTDTLSSSTHLPPR------LEPPRAHDPLADVSNDLGHS 407
            P     L P    +P  P     LS     PP       L PP    PL+    +   S
Sbjct: 496 PPPEESPLSPPPESSPFSPLEESPLSPPEESPPSPALETPLSPPPEASPLSPPFEESPLS 555

Query: 408 GRDCEHGEAAAPAPTVRLGLPLLTDCAQPSRPHGSPSRSKPKKKSKKHKDKERAAEDKPR 467
               E    + P    RL  P       P  P  SP  S P + S+     E +    P 
Sbjct: 556 PPP-EELPTSPPPEASRLSPPPEESPMSPP-PEESP-MSPPPEASRLFPPFEESPLSPPP 612

Query: 468 AQLPDCAP--ATHATPGAPADTP 488
            + P   P  A+  +P  P D+P
Sbjct: 613 EESPLSPPPEASRLSP-PPEDSP 634



 Score = 32.3 bits (72), Expect = 1.3
 Identities = 38/173 (21%), Positives = 57/173 (32%), Gaps = 22/173 (12%)

Query: 308 SSPPGERGRSASPPQKRLQPPDFIDPLANKKPRISHFTQRAQPAVNGKLGVPNGREALLP 367
           S PP E   S  P   RL PP    P++         +  + P    +L  P     L P
Sbjct: 555 SPPPEELPTSPPPEASRLSPPPEESPMSPPPEE----SPMSPPPEASRLFPPFEESPLSP 610

Query: 368 TPGPPASTDTLSSSTHLPPRLEPPRAHDPLADVSNDLGHSGRDCEHGEAAAPAPTVRLG- 426
            P     +    +S   PP  + P +  P               E    + P    RL  
Sbjct: 611 PPEESPLSPPPEASRLSPPPEDSPMSPPP---------------EESPMSPPPEVSRLSP 655

Query: 427 LPLLTDCAQP--SRPHGSPSRSKPKKKSKKHKDKERAAEDKPRAQLPDCAPAT 477
           LP+++  + P    P   P    P     +        ED P +  P+ +PA+
Sbjct: 656 LPVVSRLSPPPEESPLSPPPEESPTSPPPEASRLSPPPEDSPTSPPPEDSPAS 708


>gi|118421085 leucine-rich repeat kinase 1 [Homo sapiens]
          Length = 1910

 Score = 39.3 bits (90), Expect = 0.011
 Identities = 57/213 (26%), Positives = 79/213 (37%), Gaps = 30/213 (14%)

Query: 295  PQSTGSLLGDPAASSPPGERGRSASPPQKRLQPPDFIDPLANKKPRISHFTQRAQPAVNG 354
            P S  S    P+  +PP     +A P ++ L P    DPL    PR + F    Q   + 
Sbjct: 1213 PHSVNSSPESPSCPAPP--TSSTAQPRRECLTP--IRDPLRTP-PRAAAFMGTPQNQTHQ 1267

Query: 355  KLGVPNGREALLP----------TPGPPASTDTLSSSTHLPPRLEPPRAHDPLADVS--N 402
            +  V     A  P          TP  P ++   SS    P +L       PL DVS  +
Sbjct: 1268 QPHVLRAARAEEPAQKLKDKAIKTPKRPGNSTVTSSPPVTPKKLFT----SPLCDVSKKS 1323

Query: 403  DLGHSGRDCEH-GEAAAPAPTVRLGLPLLTDCAQPSRPHGSPSRSK-----PKKKSKKHK 456
                S  +C   GE     P +   +     C  PS P     R+      P   SK  K
Sbjct: 1324 PFRKSKIECPSPGELDQKEPQMSPSVAASLSCPVPSTPPELSQRATLDTVPPPPPSKVGK 1383

Query: 457  DKERAAEDKPRAQLPDCAPATHATPG-APADTP 488
               + ++  PR  + +C P   ATPG   AD+P
Sbjct: 1384 RCRKTSD--PRRSIVECQPDASATPGVGTADSP 1414


>gi|169207799 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 140

 Score = 38.9 bits (89), Expect = 0.014
 Identities = 36/130 (27%), Positives = 47/130 (36%), Gaps = 32/130 (24%)

Query: 362 REALLPTPGPPASTDTLSSSTHLPPRL-------EPPRAHDPLADVSNDLGHSGRDCEHG 414
           R   L TP  P +      ++ LPPR+       +PPR  D          H    C   
Sbjct: 25  RPRFLATPRVPGTP-----TSQLPPRIPGPPTTRQPPRVPD----------HLHLSCPRA 69

Query: 415 EAAAPAPTVRLGLPLLTDCAQPSRPHGSPSRSKPKKKSKKHKDKERAAEDKPRA---QLP 471
               P P+  L  P+      P+RP  +   S P+         +R   D PRA   QLP
Sbjct: 70  SPDRPRPSCPLASPIADVPPSPARPRTAHVPSAPRL-------PDRPLPDSPRASLWQLP 122

Query: 472 DCAPATHATP 481
            C P   A P
Sbjct: 123 RCFPPRRARP 132


>gi|116284398 WAS/WASL interacting protein family, member 1 [Homo
           sapiens]
          Length = 503

 Score = 38.9 bits (89), Expect = 0.014
 Identities = 57/212 (26%), Positives = 75/212 (35%), Gaps = 22/212 (10%)

Query: 299 GSLLGDPAASSPPGERGRSASPPQKRL---QPPDFIDPLANKKPRISHFTQRAQPAVNGK 355
           GS+   P +SS P        P   R    +PP    P+ N+ P I        P  N K
Sbjct: 233 GSIRQSPLSSSSPFSNRPPLPPTPSRALDDKPPPPPPPVGNR-PSIHREAVPPPPPQNNK 291

Query: 356 LGVPN----GREALLPTPGPPASTD------TLSSSTHLPPRLEPPRAHDPLADVSNDLG 405
             VP+       +  P P PP S          SS     PRL  P+ +  L+  +  L 
Sbjct: 292 PPVPSTPRPSASSQAPPPPPPPSRPGPPPLPPSSSGNDETPRL--PQRNLSLSSSTPPLP 349

Query: 406 HSGRD--CEHGEAAAPAPTVRLGLPLLTDCAQPSRP---HGSPSRSKPKKKSKKHKDKER 460
             GR        +  P P VR   P  +    P  P   +GS SR+ P       +    
Sbjct: 350 SPGRSGPLPPPPSERPPPPVR-DPPGRSGPLPPPPPVSRNGSTSRALPATPQLPSRSGVD 408

Query: 461 AAEDKPRAQLPDCAPATHATPGAPADTPGLNG 492
           +    PR  LP   P+  A P  P  T   NG
Sbjct: 409 SPRSGPRPPLPPDRPSAGAPPPPPPSTSIRNG 440


>gi|38373695 WAS/WASL interacting protein family, member 1 [Homo
           sapiens]
          Length = 503

 Score = 38.9 bits (89), Expect = 0.014
 Identities = 57/212 (26%), Positives = 75/212 (35%), Gaps = 22/212 (10%)

Query: 299 GSLLGDPAASSPPGERGRSASPPQKRL---QPPDFIDPLANKKPRISHFTQRAQPAVNGK 355
           GS+   P +SS P        P   R    +PP    P+ N+ P I        P  N K
Sbjct: 233 GSIRQSPLSSSSPFSNRPPLPPTPSRALDDKPPPPPPPVGNR-PSIHREAVPPPPPQNNK 291

Query: 356 LGVPN----GREALLPTPGPPASTD------TLSSSTHLPPRLEPPRAHDPLADVSNDLG 405
             VP+       +  P P PP S          SS     PRL  P+ +  L+  +  L 
Sbjct: 292 PPVPSTPRPSASSQAPPPPPPPSRPGPPPLPPSSSGNDETPRL--PQRNLSLSSSTPPLP 349

Query: 406 HSGRD--CEHGEAAAPAPTVRLGLPLLTDCAQPSRP---HGSPSRSKPKKKSKKHKDKER 460
             GR        +  P P VR   P  +    P  P   +GS SR+ P       +    
Sbjct: 350 SPGRSGPLPPPPSERPPPPVR-DPPGRSGPLPPPPPVSRNGSTSRALPATPQLPSRSGVD 408

Query: 461 AAEDKPRAQLPDCAPATHATPGAPADTPGLNG 492
           +    PR  LP   P+  A P  P  T   NG
Sbjct: 409 SPRSGPRPPLPPDRPSAGAPPPPPPSTSIRNG 440


>gi|45505151 nuclear factor I/C isoform 2 [Homo sapiens]
          Length = 499

 Score = 38.9 bits (89), Expect = 0.014
 Identities = 47/170 (27%), Positives = 63/170 (37%), Gaps = 30/170 (17%)

Query: 313 ERGRSASPPQKRLQPPDFIDPLANKKPRISHFTQRAQPAVNGKLGV---PNGREAL-LPT 368
           E G S+   +  +    F  P     PR+S FTQ  +P +    G+   P+   AL  PT
Sbjct: 309 EGGISSPVKKTEMDKSPFNSPSPQDSPRLSSFTQHHRPVIAVHSGIARSPHPSSALHFPT 368

Query: 369 PG---PPASTDTLSSSTHLPPRLEP--------PRAHDPLADVSNDLGHSGR-----DCE 412
                  AST    ++   PP L P          A DP +     L  SG+      C 
Sbjct: 369 TSILPQTASTYFPHTAIRYPPHLNPQDPLKDLVSLACDPASQQPGPLNGSGQLKMPSHCL 428

Query: 413 HGEAAAPAP--TVRLGLPLLTDCA--------QPSRPHGSPSRSKPKKKS 452
             +  AP P    RL LP  T  A         P+ P  SP  + P  +S
Sbjct: 429 SAQMLAPPPPGLPRLALPPATKPATTSEGGATSPTSPSYSPPDTSPANRS 478


>gi|93141049 collagen, type XII, alpha 1 short isoform precursor [Homo
            sapiens]
          Length = 1899

 Score = 38.9 bits (89), Expect = 0.014
 Identities = 44/154 (28%), Positives = 58/154 (37%), Gaps = 33/154 (21%)

Query: 303  GDPAASSPPGERGRSAS--PPQKR--LQPPDFIDPLANKKPR-ISHFTQRAQPAVNGKLG 357
            G P A  P GERG S +  PP  R  + PP    P   + P  +S   ++ +  + G  G
Sbjct: 1592 GGPGAKGPRGERGISGAIGPPGPRGDIGPPGPQGPPGPQGPNGLSIPGEQGRQGMKGDAG 1651

Query: 358  VPN--GREALLPTPGPPASTDTLSSSTHLPPRLEPPRAHDPLADVSNDLGHSGRDCEHGE 415
             P   GR      PGPP               + PP           D G +G+D   G 
Sbjct: 1652 EPGLPGRTGTPGLPGPPGP-------------MGPP----------GDRGFTGKDGAMGP 1688

Query: 416  AAAPAPTVRLGLPLLT-DCAQPSRP--HGSPSRS 446
               P P    G P +T    +P +P  HG P  S
Sbjct: 1689 RGPPGPPGSPGSPGVTGPSGKPGKPGDHGRPGPS 1722


>gi|93141047 collagen, type XII, alpha 1 long isoform precursor [Homo
            sapiens]
          Length = 3063

 Score = 38.9 bits (89), Expect = 0.014
 Identities = 44/154 (28%), Positives = 58/154 (37%), Gaps = 33/154 (21%)

Query: 303  GDPAASSPPGERGRSAS--PPQKR--LQPPDFIDPLANKKPR-ISHFTQRAQPAVNGKLG 357
            G P A  P GERG S +  PP  R  + PP    P   + P  +S   ++ +  + G  G
Sbjct: 2756 GGPGAKGPRGERGISGAIGPPGPRGDIGPPGPQGPPGPQGPNGLSIPGEQGRQGMKGDAG 2815

Query: 358  VPN--GREALLPTPGPPASTDTLSSSTHLPPRLEPPRAHDPLADVSNDLGHSGRDCEHGE 415
             P   GR      PGPP               + PP           D G +G+D   G 
Sbjct: 2816 EPGLPGRTGTPGLPGPPGP-------------MGPP----------GDRGFTGKDGAMGP 2852

Query: 416  AAAPAPTVRLGLPLLT-DCAQPSRP--HGSPSRS 446
               P P    G P +T    +P +P  HG P  S
Sbjct: 2853 RGPPGPPGSPGSPGVTGPSGKPGKPGDHGRPGPS 2886


>gi|122937496 WAS/WASL interacting protein family, member 3 [Homo
           sapiens]
          Length = 483

 Score = 38.9 bits (89), Expect = 0.014
 Identities = 47/195 (24%), Positives = 64/195 (32%), Gaps = 33/195 (16%)

Query: 306 AASSPPGERGRSASPPQKRLQPPDFIDPLANKKPRISHFTQRAQPAVNGKLGVPNGREAL 365
           A ++PP     +  PP     PP    PL +  P  +       P   G L V       
Sbjct: 162 ARTAPPRPNVPAPPPPTPPPPPPPLPPPLPSSSPIKTPLVSPPGPLTKGNLPVVAPPVPC 221

Query: 366 LPTPGPPASTDTLSSSTHLPPRLEPPRAHDPLADVSNDLGHSGRDCEHGEAAAPAPTVRL 425
            P P PP            PP   PP    P A V +D     +  +   A    P +  
Sbjct: 222 APPPPPPP-----------PPPTPPPL---PPASVLSD-----KAVKPQLAPLHLPPIPP 262

Query: 426 GLPLLTDCAQPSRPHGSPSRSKPKKKSKKHKDKERAAEDKPRAQLPDCAPATHATPGAPA 485
            LPLL  C  P        +++P   ++  ++        P A  P   P    +P A  
Sbjct: 263 PLPLLPPCGYPG------LKAEPASPAQDAQE--------PPAPPPPLPPYASCSPRASL 308

Query: 486 DTPGLNGTCSVSSVP 500
             P L G  S S  P
Sbjct: 309 PAPPLPGVNSSSETP 323



 Score = 31.2 bits (69), Expect = 3.0
 Identities = 38/140 (27%), Positives = 49/140 (35%), Gaps = 31/140 (22%)

Query: 311 PGERGRSASPPQKRLQPP---DFIDPLANKKPRISHFTQRAQPAVNGKLGVPN------- 360
           PG +   ASP Q   +PP     + P A+  PR S       P VN     P        
Sbjct: 273 PGLKAEPASPAQDAQEPPAPPPPLPPYASCSPRAS-LPAPPLPGVNSSSETPPPLPPKSP 331

Query: 361 ---------GREALLPTPGPPASTDTLSSSTHLPP-----RLEPPRAHDPLADVSNDLGH 406
                    G +AL   P PP S   L    H  P     +L PP A  P    + +L  
Sbjct: 332 SFQAPPQKAGAQALPAPPAPPGSQPFLQKKRHGRPGAGGGKLNPPPA-PPARSPTTELSS 390

Query: 407 SGRDCEHGEAAAPAPTVRLG 426
             +     +A A  PT + G
Sbjct: 391 KSQ-----QATAWTPTQQPG 405


>gi|156142180 CXXC finger 1 (PHD domain) isoform 2 [Homo sapiens]
          Length = 656

 Score = 38.5 bits (88), Expect = 0.019
 Identities = 73/341 (21%), Positives = 124/341 (36%), Gaps = 40/341 (11%)

Query: 247 QQVANMSAKDGTCTL----QDCMYKDVQKDWPGYSEGDQQLLKRVLVRKLCQPQSTGSLL 302
           QQ+   +   G C      +DC + D  +D   +  G  ++ ++  +R+ CQ ++  S  
Sbjct: 160 QQIKRSARMCGECEACRRTEDCGHCDFCRDMKKFG-GPNKIRQKCRLRQ-CQLRARESYK 217

Query: 303 GDPAASSP--PGE---RGRSASPPQKRLQPPDFIDPLANKKPRISHFTQRAQPAVNGKLG 357
             P++ SP  P E   R R   P Q++ QP   +  +   +  ++  T +  P       
Sbjct: 218 YFPSSLSPVTPSESLPRPRRPLPTQQQPQPSQKLGRIREDEGAVASSTVKEPPEATA--- 274

Query: 358 VPNGREALLPTPGPPASTDTLSSSTHLPPRLEPPRAHDPLADVSNDLGHSGR-DCEHGEA 416
                     TP P +  D       LP  L+P    D  A   +D G     D E    
Sbjct: 275 ----------TPEPLSDED-------LP--LDPDLYQDFCAGAFDDHGLPWMSDTEESPF 315

Query: 417 AAPAPTVRLGLPLLTDCAQPSRPHGSPSRSKPKKKSKKHKDKER---AAEDKPRAQLPDC 473
             PA   R          +         R K  ++ +KHKDK +    A+ K  A LP C
Sbjct: 316 LDPALRKRAVKVKHVKRREKKSEKKKEERYKRHRQKQKHKDKWKHPERADAKDPASLPQC 375

Query: 474 APATHATPGAPADTPGLNGTCSVSSVPTSTSETPDYLLKYAAISSSEQRQSYKNDFNAEY 533
                  P  P+ +   +  C +        E     ++    S     +  K       
Sbjct: 376 LGPGCVRPAQPS-SKYCSDDCGMKLAANRIYEILPQRIQQWQQSPCIAEEHGKKLLERIR 434

Query: 534 SEYRDLHARIERITRRFTQLDAQLRQLSQGS--EEYETTRG 572
            E +    R++ + RRF +L+A + +  Q +  E+ E+  G
Sbjct: 435 REQQSARTRLQEMERRFHELEAIILRAKQQAVREDEESNEG 475


>gi|147905592 coiled-coil domain containing 102B [Homo sapiens]
          Length = 513

 Score = 38.5 bits (88), Expect = 0.019
 Identities = 29/116 (25%), Positives = 54/116 (46%), Gaps = 15/116 (12%)

Query: 501 TSTSETPDYLLKYAAISSSEQRQSYKNDFNAEYSEYRDLHARIERITRRFTQLDA----- 555
           ++ S++PD+  K + I   E+ Q   N  +A Y   R   A I  +T    ++D      
Sbjct: 401 SANSQSPDF--KMSQIDLQEKNQELLNLQHAYYKLNRQYQANIAELTHANNRVDQNEAEV 458

Query: 556 -----QLRQLSQGSEEYETTRGQILQEYRKIKKTNTNYSQEKHRCEYLHSKLAHIK 606
                ++ +L QG  + E      L + RK+++   +  +EK R E L ++L H++
Sbjct: 459 KKLRLRVEELKQGLNQKEDELDDSLNQIRKLQR---SLDEEKERNENLETELRHLQ 511


>gi|148233522 coiled-coil domain containing 102B [Homo sapiens]
          Length = 513

 Score = 38.5 bits (88), Expect = 0.019
 Identities = 29/116 (25%), Positives = 54/116 (46%), Gaps = 15/116 (12%)

Query: 501 TSTSETPDYLLKYAAISSSEQRQSYKNDFNAEYSEYRDLHARIERITRRFTQLDA----- 555
           ++ S++PD+  K + I   E+ Q   N  +A Y   R   A I  +T    ++D      
Sbjct: 401 SANSQSPDF--KMSQIDLQEKNQELLNLQHAYYKLNRQYQANIAELTHANNRVDQNEAEV 458

Query: 556 -----QLRQLSQGSEEYETTRGQILQEYRKIKKTNTNYSQEKHRCEYLHSKLAHIK 606
                ++ +L QG  + E      L + RK+++   +  +EK R E L ++L H++
Sbjct: 459 KKLRLRVEELKQGLNQKEDELDDSLNQIRKLQR---SLDEEKERNENLETELRHLQ 511


>gi|223633935 hypothetical protein LOC254427 [Homo sapiens]
          Length = 435

 Score = 38.1 bits (87), Expect = 0.024
 Identities = 54/204 (26%), Positives = 78/204 (38%), Gaps = 31/204 (15%)

Query: 326 QPPDFID-----PLANKKPRISHFTQRAQPAVNGKLGVPNGREALLPTPGPPASTDTLSS 380
           +P D ID     P A +   +   TQ A PA  GK      ++A  P P  P + +TL +
Sbjct: 103 EPEDVIDLVQPAPGAGEAEGLPEGTQAAGPAPAGK--EHRKQDAETPPPPDPPAPETLLA 160

Query: 381 STHLPPRLEPPRAHDPLADVSNDLGHSGRDCEHGEAAAPAPTVRLGLPLLTDCAQPSRPH 440
              LP   +PPR          +L       EH       PT     PL+       R  
Sbjct: 161 PPPLPSTPDPPR---------RELRAPSPPVEHPRLLRSVPT-----PLVMAQKISERMA 206

Query: 441 GSP--SRSKPKKKSKKHKDKERAAEDKPRAQLPDCAPATHATPGAPADTPGLNGTCSVSS 498
           G+   S + P ++ +  + +  AA   PR+  P   P+  A P AP     +  T   + 
Sbjct: 207 GNEALSPTSPFREGRPGEWRTPAARG-PRSGDPGPGPSHPAQPKAPRFPSNIIVTNGAAR 265

Query: 499 VPTSTSETPDYLLKYAAISSSEQR 522
            P  T       L  AA+S  E+R
Sbjct: 266 EPRRT-------LSRAAVSVQERR 282


>gi|116008152 alpha 1 type XV collagen precursor [Homo sapiens]
          Length = 1388

 Score = 38.1 bits (87), Expect = 0.024
 Identities = 50/179 (27%), Positives = 62/179 (34%), Gaps = 36/179 (20%)

Query: 279 GDQQLLKRVLVRKLCQPQSTGSLLGDPAASSPPGERGRSAS----PPQKRLQPPDFIDPL 334
           G  QLL      KL +P +   L G+     P GERG   +    PP  R  PP  I  L
Sbjct: 746 GSTQLLNEP---KLSRPTAAIGLKGEKGDRGPKGERGMDGASIVGPPGPR-GPPGHIKVL 801

Query: 335 ANKKPRISHFTQRAQ--PAVNGKLGVPNGREALLPTPGPPASTDTLSSSTHLPPRLEPPR 392
           +N    I+H        P + G  G P+G   L   PGP          T LP       
Sbjct: 802 SNSLINITHGFMNFSDIPELVGPPG-PDGLPGLPGFPGPRGP----KGDTGLP------- 849

Query: 393 AHDPLADVSNDLGHSGRDCEHGEAAAPAPTVRLGLPLLTDCAQPSRP--HGSPSRSKPK 449
                       G  G   E GE   P   +   +PL     +   P  HG+P    PK
Sbjct: 850 ------------GFPGLKGEQGEKGEPGAILTEDIPLERLMGKKGEPGMHGAPGPMGPK 896


>gi|239752594 PREDICTED: hypothetical protein, partial [Homo
           sapiens]
          Length = 673

 Score = 38.1 bits (87), Expect = 0.024
 Identities = 52/238 (21%), Positives = 81/238 (34%), Gaps = 34/238 (14%)

Query: 292 LCQPQSTGSLLGDPAASSPPGERGRSASPPQKRLQPPDFIDPLANKKPR--ISHFTQRAQ 349
           L    ST SL+     +SP G   R++      L   D    ++   PR  I+    RA 
Sbjct: 295 LSMTPSTASLMRMLPRASPTGMLSRTS------LTKMDSTASISRTPPRASITRTPSRAS 348

Query: 350 PAVNGKLGVPNGREALLPTPGPPASTDTLSSSTHLPPRLEPPRAHDPLADVSNDLGHSGR 409
           P        P G  +     G P++      S+   P   PPRA  P    S     +  
Sbjct: 349 PTGKPSTASPTGTPSRASPTGSPSTASLTGLSSTASPTGTPPRA-SPTGTPST----ASL 403

Query: 410 DCEHGEAAAPAPTVRLGLPLLTDCAQPSR------PHGSPSRSK----PKKKSKKHKDKE 459
             +   A+      R  +  +   A P+R      P G+P R+     P + S       
Sbjct: 404 TRKPPRASPTGMLSRTSITKMDSTASPTRTPPRASPTGTPPRASPTGTPSRASPTGTQST 463

Query: 460 RAAEDKPRAQLPDCAPATHATPGAP-----------ADTPGLNGTCSVSSVPTSTSET 506
            +    P    P  +P+T +  G+P           A    +  T S++  P+  S T
Sbjct: 464 ASPTGSPSTASPTGSPSTASPTGSPSRASLTRTPSRASLTKMESTASITRTPSRASPT 521


>gi|167614488 TBC1 domain family, member 10B [Homo sapiens]
          Length = 808

 Score = 38.1 bits (87), Expect = 0.024
 Identities = 62/232 (26%), Positives = 78/232 (33%), Gaps = 35/232 (15%)

Query: 303 GDPAASSPPGERGRSASPPQKRLQPPDFIDPLANKKPRISHFTQRAQPAVNGKLGVPNGR 362
           G PAA SPP  RG  A P       P      A   P        A+PA      VP   
Sbjct: 16  GAPAAPSPP-PRGSRAGPVVVVAPGPPVTT--ATSAPVTLVAPGEARPA-----WVPGSA 67

Query: 363 EALLPTPGP-----PASTD------TLSSSTHLPPRLEP--PRAHDPLADVSNDLGHS-- 407
           E   P P P     PA T       TL +S   P    P  P + +P A    +   +  
Sbjct: 68  ETSAPAPAPAPAPAPAVTGSTVVVLTLEASPEAPKPQLPSGPESPEPAAVAGVETSRALA 127

Query: 408 -GRDCEHGEAAAPAPTVRLGLPLLTDCAQPSRPHGSPSRSKPKKKSKKHKD-----KERA 461
            G D    E A P+P    G P  T    PSR       +KP    K           R+
Sbjct: 128 AGADSPKTEEARPSPAPGPGTPTGTPTRTPSRTAPGALTAKPPLAPKPGTTVASGVTARS 187

Query: 462 AEDKPRAQLPDCAPATHATPGAPADTP-----GLNGTCSVSSVPTSTSETPD 508
           A  +        A AT A+ G   + P     G +GTC       + +  P+
Sbjct: 188 ASGQVTGG-HGAAAATSASAGQAPEDPSGPGTGPSGTCEAPVAVVTVTPAPE 238


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.314    0.130    0.380 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 27,200,827
Number of Sequences: 37866
Number of extensions: 1484479
Number of successful extensions: 8210
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 48
Number of HSP's successfully gapped in prelim test: 445
Number of HSP's that attempted gapping in prelim test: 7086
Number of HSP's gapped (non-prelim): 1520
length of query: 621
length of database: 18,247,518
effective HSP length: 108
effective length of query: 513
effective length of database: 14,157,990
effective search space: 7263048870
effective search space used: 7263048870
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (22.0 bits)
S2: 65 (29.6 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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