Guide to the Human Genome
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Search of human proteins with 5729783

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|5729783 complexin 2 [Homo sapiens]
         (134 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|56550065 complexin 2 [Homo sapiens]                                269   6e-73
gi|5729783 complexin 2 [Homo sapiens]                                 269   6e-73
gi|5729781 complexin 1 [Homo sapiens]                                 228   1e-60
gi|71725345 complexin 3 [Homo sapiens]                                 62   2e-10
gi|66792814 retrotransposon gag domain containing 4 [Homo sapiens]     55   2e-08
gi|148746183 ubiquitin specific protease 35 [Homo sapiens]             54   3e-08
gi|221219020 NYD-SP11 protein [Homo sapiens]                           50   7e-07
gi|239754909 PREDICTED: hypothetical protein [Homo sapiens]            49   9e-07
gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-li...    49   1e-06
gi|148746195 trichohyalin [Homo sapiens]                               47   4e-06
gi|22758136 MAP7 domain containing 2 [Homo sapiens]                    47   4e-06
gi|31795561 complexin 4 [Homo sapiens]                                 47   5e-06
gi|55741709 RNA binding motif protein 25 [Homo sapiens]                45   2e-05
gi|239745079 PREDICTED: Putative golgin subfamily A member 6-lik...    45   2e-05
gi|78190492 retinitis pigmentosa GTPase regulator isoform C [Hom...    44   3e-05
gi|157738649 neurofilament, medium polypeptide 150kDa isoform 1 ...    44   4e-05
gi|157738641 neurofilament, medium polypeptide 150kDa isoform 2 ...    44   4e-05
gi|239508778 PREDICTED: hypothetical protein, partial [Homo sapi...    44   5e-05
gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo sa...    43   7e-05
gi|115298682 HBxAg transactivated protein 2 [Homo sapiens]             43   7e-05
gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo sa...    42   1e-04
gi|195927037 DNA (cytosine-5-)-methyltransferase 1 isoform a [Ho...    42   1e-04
gi|4503351 DNA (cytosine-5-)-methyltransferase 1 isoform b [Homo...    42   1e-04
gi|148806928 hypothetical protein LOC57482 [Homo sapiens]              42   1e-04
gi|155030232 proline, glutamic acid and leucine rich protein 1 [...    42   1e-04
gi|18426913 drebrin 1 isoform b [Homo sapiens]                         42   1e-04
gi|18426915 drebrin 1 isoform a [Homo sapiens]                         42   1e-04
gi|239749449 PREDICTED: hypothetical protein [Homo sapiens]            42   2e-04
gi|40254924 leucine rich repeat containing 59 [Homo sapiens]           42   2e-04
gi|190684694 ubiquitin specific peptidase 8 [Homo sapiens]             42   2e-04

>gi|56550065 complexin 2 [Homo sapiens]
          Length = 134

 Score =  269 bits (687), Expect = 6e-73
 Identities = 134/134 (100%), Positives = 134/134 (100%)

Query: 1   MDFVMKQALGGATKDMGKMLGGEEEKDPDAQKKEEERQEALRQQEEERKAKHARMEAERE 60
           MDFVMKQALGGATKDMGKMLGGEEEKDPDAQKKEEERQEALRQQEEERKAKHARMEAERE
Sbjct: 1   MDFVMKQALGGATKDMGKMLGGEEEKDPDAQKKEEERQEALRQQEEERKAKHARMEAERE 60

Query: 61  KVRQQIRDKYGLKKKEEKEAEEKAALEQPCEGSLTRPKKAIPAGCGDEEEEEEESILDTV 120
           KVRQQIRDKYGLKKKEEKEAEEKAALEQPCEGSLTRPKKAIPAGCGDEEEEEEESILDTV
Sbjct: 61  KVRQQIRDKYGLKKKEEKEAEEKAALEQPCEGSLTRPKKAIPAGCGDEEEEEEESILDTV 120

Query: 121 LKYLPGPLQDMFKK 134
           LKYLPGPLQDMFKK
Sbjct: 121 LKYLPGPLQDMFKK 134


>gi|5729783 complexin 2 [Homo sapiens]
          Length = 134

 Score =  269 bits (687), Expect = 6e-73
 Identities = 134/134 (100%), Positives = 134/134 (100%)

Query: 1   MDFVMKQALGGATKDMGKMLGGEEEKDPDAQKKEEERQEALRQQEEERKAKHARMEAERE 60
           MDFVMKQALGGATKDMGKMLGGEEEKDPDAQKKEEERQEALRQQEEERKAKHARMEAERE
Sbjct: 1   MDFVMKQALGGATKDMGKMLGGEEEKDPDAQKKEEERQEALRQQEEERKAKHARMEAERE 60

Query: 61  KVRQQIRDKYGLKKKEEKEAEEKAALEQPCEGSLTRPKKAIPAGCGDEEEEEEESILDTV 120
           KVRQQIRDKYGLKKKEEKEAEEKAALEQPCEGSLTRPKKAIPAGCGDEEEEEEESILDTV
Sbjct: 61  KVRQQIRDKYGLKKKEEKEAEEKAALEQPCEGSLTRPKKAIPAGCGDEEEEEEESILDTV 120

Query: 121 LKYLPGPLQDMFKK 134
           LKYLPGPLQDMFKK
Sbjct: 121 LKYLPGPLQDMFKK 134


>gi|5729781 complexin 1 [Homo sapiens]
          Length = 134

 Score =  228 bits (581), Expect = 1e-60
 Identities = 113/134 (84%), Positives = 123/134 (91%)

Query: 1   MDFVMKQALGGATKDMGKMLGGEEEKDPDAQKKEEERQEALRQQEEERKAKHARMEAERE 60
           M+FVMKQALGGATKDMGKMLGG+EEKDPDA KKEEERQEALRQ EEERKAK+A+MEAERE
Sbjct: 1   MEFVMKQALGGATKDMGKMLGGDEEKDPDAAKKEEERQEALRQAEEERKAKYAKMEAERE 60

Query: 61  KVRQQIRDKYGLKKKEEKEAEEKAALEQPCEGSLTRPKKAIPAGCGDEEEEEEESILDTV 120
            VRQ IRDKYG+KKKEE+EAE +AA+E   EGSLTRPKKAIP GCGDE EEE+ESILDTV
Sbjct: 61  AVRQGIRDKYGIKKKEEREAEAQAAMEANSEGSLTRPKKAIPPGCGDEVEEEDESILDTV 120

Query: 121 LKYLPGPLQDMFKK 134
           +KYLPGPLQDM KK
Sbjct: 121 IKYLPGPLQDMLKK 134


>gi|71725345 complexin 3 [Homo sapiens]
          Length = 158

 Score = 61.6 bits (148), Expect = 2e-10
 Identities = 45/136 (33%), Positives = 70/136 (51%), Gaps = 15/136 (11%)

Query: 1   MDFVMKQALGGATKDM-GKMLGGEEEKDPDAQKKE---------EERQEALRQQEEERKA 50
           M F++K  +GG  K++ G + GGE++ D D    E         EE Q+ L +++ ER A
Sbjct: 1   MAFMVKTMVGGQLKNLTGSLGGGEDKGDGDKSAAEAQGMSREEYEEYQKQLVEEKMERDA 60

Query: 51  KHARMEAEREKVRQQIRDKYGLKKKEEKEAEEKAALEQPCEGSLTRPKKAIPAGCGDEEE 110
           +  + +AER  +R   RDKY L K E  E++ + A      G +  P++       D EE
Sbjct: 61  QFTQRKAERATLRSHFRDKYRLPKNETDESQIQMA-----GGDVELPRELAKMIEEDTEE 115

Query: 111 EEEESILDTVLKYLPG 126
           EEE++ +   L  LPG
Sbjct: 116 EEEKASVLGQLASLPG 131


>gi|66792814 retrotransposon gag domain containing 4 [Homo sapiens]
          Length = 569

 Score = 55.1 bits (131), Expect = 2e-08
 Identities = 32/95 (33%), Positives = 53/95 (55%), Gaps = 3/95 (3%)

Query: 23  EEEKDPDAQKKEEERQEALRQQ---EEERKAKHARMEAEREKVRQQIRDKYGLKKKEEKE 79
           EEE + +    E+E QEA R +   +++RK   A  +  +EK  ++++ +  +KKKEEKE
Sbjct: 335 EEESEDEEYYSEDEDQEARRHRLHSKDQRKRMRAFQQEMKEKEEEEMKKEEEMKKKEEKE 394

Query: 80  AEEKAALEQPCEGSLTRPKKAIPAGCGDEEEEEEE 114
            EE+  ++Q  E    R K        DEE+E+E+
Sbjct: 395 EEEEEEMKQKEEEEEIRNKNEEEGESKDEEDEDED 429



 Score = 38.1 bits (87), Expect = 0.002
 Identities = 27/90 (30%), Positives = 49/90 (54%), Gaps = 4/90 (4%)

Query: 31  QKKEEERQEALRQQEEERKAKHARMEAEREKVRQQIRDKYGLKKKEEKEAEEKAALEQPC 90
           Q++ +E++E   ++EEE K K  + E E E+++Q+  ++  ++ K E+E E K   ++  
Sbjct: 370 QQEMKEKEEEEMKKEEEMKKKEEKEEEEEEEMKQK-EEEEEIRNKNEEEGESKDEEDEDE 428

Query: 91  EGSLTRPKKAIPAGCGDEEE--EEEESILD 118
           +G   +P+       G EE   E EE  LD
Sbjct: 429 DGG-QKPEGEPQQDPGTEETYGEVEEEPLD 457



 Score = 34.7 bits (78), Expect = 0.024
 Identities = 19/65 (29%), Positives = 38/65 (58%), Gaps = 1/65 (1%)

Query: 23  EEEKDPDAQKKEEERQEALRQQEEERKAKHARMEAEREKVRQQIRDKYGLKKKEEKEAEE 82
           +EE+    ++KEEE +E ++Q+EEE + ++ + E E E   ++  D+ G +K E +  ++
Sbjct: 383 KEEEMKKKEEKEEEEEEEMKQKEEEEEIRN-KNEEEGESKDEEDEDEDGGQKPEGEPQQD 441

Query: 83  KAALE 87
               E
Sbjct: 442 PGTEE 446


>gi|148746183 ubiquitin specific protease 35 [Homo sapiens]
          Length = 1018

 Score = 54.3 bits (129), Expect = 3e-08
 Identities = 33/107 (30%), Positives = 58/107 (54%), Gaps = 2/107 (1%)

Query: 18  KMLGGEEEKDPDAQKKEEERQEALRQQEEERKAKHARMEAEREKVRQQIRDKYGLKKKEE 77
           K  GG+  ++   +++EE ++E   ++E   + +  R E EREK  +   ++  ++K+ E
Sbjct: 665 KEAGGQSSQEERIEREEEGKEERTEKEEVGEEEESTRGEGEREKEEEVEEEEEKVEKETE 724

Query: 78  KEAEEKAALEQPCEGSLTRPKKAIPAGCGDEEEEEEESILDTVLKYL 124
           KEAE++   E+   G+ T P  AIP+G      E   S+LD V  +L
Sbjct: 725 KEAEQEK--EEDSLGAGTHPDAAIPSGERTCGSEGSRSVLDLVNYFL 769


>gi|221219020 NYD-SP11 protein [Homo sapiens]
          Length = 2873

 Score = 49.7 bits (117), Expect = 7e-07
 Identities = 31/94 (32%), Positives = 52/94 (55%), Gaps = 5/94 (5%)

Query: 25   EKDPDAQKKEEERQEALRQQEEERKAKHARMEAEREKVRQQIRDKYGLKKKEEKEAEEKA 84
            E++ + +++EE  +E +R++EEERK +    E E ++V ++  +K   KKK+EK+ EE  
Sbjct: 2246 EEEEEREEEEEREEEEVREEEEERKEEE---EGEEKQVEKEEEEK--KKKKKEKKKEEVQ 2300

Query: 85   ALEQPCEGSLTRPKKAIPAGCGDEEEEEEESILD 118
              E+  E       +       DEEEEEE   L+
Sbjct: 2301 EKEEVFEEKEEIMSEEETESLSDEEEEEESCSLE 2334



 Score = 36.2 bits (82), Expect = 0.008
 Identities = 26/67 (38%), Positives = 37/67 (55%), Gaps = 3/67 (4%)

Query: 23   EEEKDPDAQKKEEERQEALRQ-QEEERKAKHARMEAEREKVRQQIRDKYGLKKKEEKEAE 81
            EEE   + ++KE++  E  R  QEE + A+  R  A  EK R Q   K  L ++EEK A+
Sbjct: 1547 EEEVSREGEEKEQQVTEEQRHIQEEHKWARIHRKRARAEKKRAQEERK--LAQEEEKLAQ 1604

Query: 82   EKAALEQ 88
            E+  L Q
Sbjct: 1605 EERQLAQ 1611



 Score = 33.1 bits (74), Expect = 0.069
 Identities = 24/80 (30%), Positives = 40/80 (50%), Gaps = 3/80 (3%)

Query: 20   LGGEEEKDPDAQKKEEERQEALRQQEEERKAKHARMEAEREKVRQQIRDKYGLKKKEEKE 79
            L  EE K  + +KK  E +EAL  Q E+   +  ++  E E +   I++K  L + +EK 
Sbjct: 1735 LNQEEGKLVEEKKKLAEEEEALAWQREKLSEEETKLAQEEELL---IQEKEKLAQHKEKM 1791

Query: 80   AEEKAALEQPCEGSLTRPKK 99
             EE+  L +  E  + +  K
Sbjct: 1792 PEEEERLGRKREQLIEKKMK 1811



 Score = 32.7 bits (73), Expect = 0.089
 Identities = 28/81 (34%), Positives = 41/81 (50%), Gaps = 7/81 (8%)

Query: 44   QEEERKAKHARMEAEREKVRQQIRDKYGLKKKEEKEAEEKAALEQPCEGSLTRPKKAIPA 103
            QE+E   K     AE EK   Q+ D   L KK+EK A+EK  L    E ++ + KK +  
Sbjct: 1897 QEKETVIKKKEKLAETEKKLVQVEDS--LAKKQEKLAQEKMKL--ALEKAMVQGKKRLR- 1951

Query: 104  GCGDEEEEEEESILDTVLKYL 124
              G+ +  +EE  L+  +K L
Sbjct: 1952 --GELDIAKEEKALNLEMKRL 1970



 Score = 30.4 bits (67), Expect = 0.44
 Identities = 16/66 (24%), Positives = 38/66 (57%), Gaps = 1/66 (1%)

Query: 23   EEEKDPDAQKKEEERQEALRQQEEERKAKHARMEAEREKVRQQIRDKYGLKKKEEKEAEE 82
            EEE+  + Q ++EE ++  +++E++++    + E   EK  + + ++      +E+E EE
Sbjct: 2271 EEEEGEEKQVEKEEEEKKKKKKEKKKEEVQEKEEVFEEK-EEIMSEEETESLSDEEEEEE 2329

Query: 83   KAALEQ 88
              +LE+
Sbjct: 2330 SCSLEE 2335



 Score = 30.4 bits (67), Expect = 0.44
 Identities = 16/62 (25%), Positives = 37/62 (59%), Gaps = 1/62 (1%)

Query: 23   EEEKDPDAQKKEEERQEALRQQEEERKAKHARM-EAEREKVRQQIRDKYGLKKKEEKEAE 81
            E+E++   +KK+E+++E ++++EE  + K   M E E E +  +  ++     +EE + E
Sbjct: 2281 EKEEEEKKKKKKEKKKEEVQEKEEVFEEKEEIMSEEETESLSDEEEEEESCSLEEEVDRE 2340

Query: 82   EK 83
            ++
Sbjct: 2341 KE 2342



 Score = 28.9 bits (63), Expect = 1.3
 Identities = 26/102 (25%), Positives = 46/102 (45%), Gaps = 10/102 (9%)

Query: 23   EEEKDPDAQKKEEERQEALR----------QQEEERKAKHARMEAEREKVRQQIRDKYGL 72
            EEE  P  +++  +R+EA R          Q +E    +H   E E      + ++    
Sbjct: 2186 EEEVIPFLKRRWRKRKEAKRGDKPKEKFSSQVDEVESEEHFSEEMESLLDELEKQESLSS 2245

Query: 73   KKKEEKEAEEKAALEQPCEGSLTRPKKAIPAGCGDEEEEEEE 114
            +++EE+E EE+   E+  E    R ++        E+EEEE+
Sbjct: 2246 EEEEEREEEEEREEEEVREEEEERKEEEEGEEKQVEKEEEEK 2287



 Score = 28.9 bits (63), Expect = 1.3
 Identities = 17/64 (26%), Positives = 35/64 (54%), Gaps = 3/64 (4%)

Query: 23   EEEKDPDAQKKEE---ERQEALRQQEEERKAKHARMEAEREKVRQQIRDKYGLKKKEEKE 79
            +E+K  + Q+KEE   E++E + ++E E  +     E       +  R+K  LKK+++ +
Sbjct: 2292 KEKKKEEVQEKEEVFEEKEEIMSEEETESLSDEEEEEESCSLEEEVDREKEILKKEKQFK 2351

Query: 80   AEEK 83
             +E+
Sbjct: 2352 LQEQ 2355



 Score = 28.5 bits (62), Expect = 1.7
 Identities = 17/59 (28%), Positives = 32/59 (54%), Gaps = 4/59 (6%)

Query: 24   EEKDPDAQKKEE----ERQEALRQQEEERKAKHARMEAEREKVRQQIRDKYGLKKKEEK 78
            +EK+   ++KEE    E  E+L  +EEE ++     E +REK   +   ++ L+++  K
Sbjct: 2300 QEKEEVFEEKEEIMSEEETESLSDEEEEEESCSLEEEVDREKEILKKEKQFKLQEQRRK 2358



 Score = 28.1 bits (61), Expect = 2.2
 Identities = 19/59 (32%), Positives = 30/59 (50%), Gaps = 1/59 (1%)

Query: 30   AQKKEEERQEALRQQEEERKAKHARMEAEREKVRQQIRDKYGLKKKEEKEAEEKAALEQ 88
            A+KK  + +  L Q EEE+ A+  R  A+ E+   Q   K     +E  +AE K A ++
Sbjct: 1584 AEKKRAQEERKLAQ-EEEKLAQEERQLAQEERKLAQAYVKITQDDREMAQAEGKFAQKE 1641



 Score = 27.7 bits (60), Expect = 2.9
 Identities = 22/81 (27%), Positives = 38/81 (46%), Gaps = 6/81 (7%)

Query: 24   EEKDPDAQKKEEERQEALRQQE-----EERKAKHARMEAEREKVRQQIRDKYGLKKKEEK 78
            E+K    ++K  + +E L Q+E     EERK   A ++  ++  R+  + +    +KEE 
Sbjct: 1585 EKKRAQEERKLAQEEEKLAQEERQLAQEERKLAQAYVKITQDD-REMAQAEGKFAQKEET 1643

Query: 79   EAEEKAALEQPCEGSLTRPKK 99
             A+    L Q  E    + KK
Sbjct: 1644 LAQRGEKLSQEAEKLAQKRKK 1664



 Score = 27.7 bits (60), Expect = 2.9
 Identities = 34/121 (28%), Positives = 56/121 (46%), Gaps = 17/121 (14%)

Query: 6    KQALGGATKDMGKMLGGEEEKDPDAQKKEEERQEALRQQEEERKAKHARMEAEREKVRQQ 65
            +Q L    K++ + L   E    +   KEEE       QEE +  +  +  AE E+    
Sbjct: 1704 EQNLDWQEKELAQELEELEWDMEELSWKEEE-----LNQEEGKLVEEKKKLAEEEEALAW 1758

Query: 66   IRDKYGLKKKEEKEAEEKAALEQPCEGSLTRPKKAIPAGCGDEEEE----EEESILDTVL 121
             R+K  L ++E K A+E+  L Q  E  L + K+ +P     EEEE    + E +++  +
Sbjct: 1759 QREK--LSEEETKLAQEEELLIQEKE-KLAQHKEKMP-----EEEERLGRKREQLIEKKM 1810

Query: 122  K 122
            K
Sbjct: 1811 K 1811



 Score = 26.9 bits (58), Expect = 4.9
 Identities = 19/79 (24%), Positives = 39/79 (49%), Gaps = 4/79 (5%)

Query: 17   GKMLGGEEEKDPDAQKKEEERQEALRQQEEERKAKHARMEAEREKVRQQIRD----KYGL 72
            G+ L  E EK    +KK  ++ E + ++EE+   K  ++   +  + Q++ +    +  L
Sbjct: 1648 GEKLSQEAEKLAQKRKKLAKKWEKVAREEEKLAKKGGKLAEVKNILAQKVEELPQREQNL 1707

Query: 73   KKKEEKEAEEKAALEQPCE 91
              +E++ A+E   LE   E
Sbjct: 1708 DWQEKELAQELEELEWDME 1726



 Score = 26.9 bits (58), Expect = 4.9
 Identities = 23/83 (27%), Positives = 40/83 (48%), Gaps = 12/83 (14%)

Query: 24   EEKDPDAQKKEE--ERQEALRQQEEERKAKHARMEAERE----------KVRQQIRDKYG 71
            +EK+  AQ KE+  E +E L ++ E+   K  ++  +RE          K +  +  K  
Sbjct: 1779 QEKEKLAQHKEKMPEEEERLGRKREQLIEKKMKLAQKRERWINSMEELTKNKMILYQKKN 1838

Query: 72   LKKKEEKEAEEKAALEQPCEGSL 94
            L ++++  A+EK  L Q  E  L
Sbjct: 1839 LAQEKKNLAQEKEKLAQRKENLL 1861



 Score = 26.6 bits (57), Expect = 6.4
 Identities = 24/84 (28%), Positives = 36/84 (42%), Gaps = 10/84 (11%)

Query: 5    MKQALGGATKDMGKMLGGEEEKDPDAQKKEEE-----RQEALRQQEEERKAKHARMEAER 59
            + Q  G   ++  K+   EE      +K  EE     ++E L  QE+E+ A+H     E 
Sbjct: 1735 LNQEEGKLVEEKKKLAEEEEALAWQREKLSEEETKLAQEEELLIQEKEKLAQHKEKMPEE 1794

Query: 60   E-----KVRQQIRDKYGLKKKEEK 78
            E     K  Q I  K  L +K E+
Sbjct: 1795 EERLGRKREQLIEKKMKLAQKRER 1818


>gi|239754909 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 245

 Score = 49.3 bits (116), Expect = 9e-07
 Identities = 27/93 (29%), Positives = 52/93 (55%), Gaps = 5/93 (5%)

Query: 22  GEEEKDPDAQKKEEERQEALRQQEEERKAKHARMEAEREKVRQQIRDKYGLKKKEEKEAE 81
           G++E++ + +K+  ER++  R++E+ERK +  + E + E+ +++   K   ++KE KE E
Sbjct: 51  GKKERESERKKERREREKRKREREKERKRERGKKEKKGERKKEERERKKRRREKENKEGE 110

Query: 82  EKAALEQPCEGSLTRPKKAIPAGCGDEEEEEEE 114
           EK   ++  +    R  K      G E E +EE
Sbjct: 111 EKEKRKKKEKKERGRTSKE-----GKERERKEE 138



 Score = 43.9 bits (102), Expect = 4e-05
 Identities = 27/99 (27%), Positives = 52/99 (52%), Gaps = 6/99 (6%)

Query: 22  GEEEKDPDAQKKEEERQEALRQ------QEEERKAKHARMEAEREKVRQQIRDKYGLKKK 75
           G++EK  + +K+E ER++  R+      +E+E++ K  + E  R     + R++   +K+
Sbjct: 82  GKKEKKGERKKEERERKKRRREKENKEGEEKEKRKKKEKKERGRTSKEGKERERKEERKR 141

Query: 76  EEKEAEEKAALEQPCEGSLTRPKKAIPAGCGDEEEEEEE 114
           EE++  E+   E+  E      KK      G++EEE +E
Sbjct: 142 EERKERERKKEEREKERERKERKKRERKQVGEKEEERKE 180



 Score = 40.8 bits (94), Expect = 3e-04
 Identities = 23/70 (32%), Positives = 41/70 (58%), Gaps = 6/70 (8%)

Query: 14  KDMGKMLGGEEEKDPDAQKKEEERQEALRQQEEERKAKHARMEAEREKVRQQIRDKYGLK 73
           K+ G+     +E++   ++K EER+E  R++EE  K      E ER++ +++ R + G K
Sbjct: 121 KERGRTSKEGKERERKEERKREERKERERKKEEREK------ERERKERKKRERKQVGEK 174

Query: 74  KKEEKEAEEK 83
           ++E KE E K
Sbjct: 175 EEERKEKERK 184



 Score = 40.4 bits (93), Expect = 4e-04
 Identities = 24/94 (25%), Positives = 50/94 (53%), Gaps = 2/94 (2%)

Query: 23  EEEKDPDAQKKEEERQEALR--QQEEERKAKHARMEAEREKVRQQIRDKYGLKKKEEKEA 80
           +EE++ + ++KE +++E  +  ++EEERK K  +   +RE+ R++ + +   K++ E++ 
Sbjct: 151 KEEREKERERKERKKRERKQVGEKEEERKEKERKERKKRERNRKERKKERERKERRERKK 210

Query: 81  EEKAALEQPCEGSLTRPKKAIPAGCGDEEEEEEE 114
           E K   E+  E    R         G  E +E +
Sbjct: 211 ERKKKEERKKERQKDRQTNWREKERGKRERKERK 244



 Score = 39.7 bits (91), Expect = 7e-04
 Identities = 24/80 (30%), Positives = 47/80 (58%), Gaps = 6/80 (7%)

Query: 23  EEEKDPDAQKKEEERQEALRQQEEERKAKHARMEAEREKVRQQIR---DKYGLKKKEEKE 79
           E E++ + +K+ ++ +E+ R++E   + K  R   EREK R++ R   +K G +KKEE+E
Sbjct: 40  EREREIETRKEGKKERESERKKERREREKRKR---EREKERKRERGKKEKKGERKKEERE 96

Query: 80  AEEKAALEQPCEGSLTRPKK 99
            +++   ++  EG     +K
Sbjct: 97  RKKRRREKENKEGEEKEKRK 116



 Score = 39.3 bits (90), Expect = 0.001
 Identities = 28/97 (28%), Positives = 48/97 (49%), Gaps = 9/97 (9%)

Query: 11  GATKDMGKMLGGEEEKDPDAQKKEEERQEALRQQEEERKAKHARM--------EAEREKV 62
           G T   GK    +EE+  + ++KE ER++  R++E ERK +  R         E  +EK 
Sbjct: 124 GRTSKEGKERERKEERKRE-ERKERERKKEEREKERERKERKKRERKQVGEKEEERKEKE 182

Query: 63  RQQIRDKYGLKKKEEKEAEEKAALEQPCEGSLTRPKK 99
           R++ + +   +K+ +KE E K   E+  E      +K
Sbjct: 183 RKERKKRERNRKERKKERERKERRERKKERKKKEERK 219



 Score = 35.8 bits (81), Expect = 0.011
 Identities = 15/66 (22%), Positives = 40/66 (60%)

Query: 18  KMLGGEEEKDPDAQKKEEERQEALRQQEEERKAKHARMEAEREKVRQQIRDKYGLKKKEE 77
           K +G +EE+  + ++KE +++E  R++ ++ + +  R E ++E+ +++ R K   K ++ 
Sbjct: 169 KQVGEKEEERKEKERKERKKRERNRKERKKERERKERRERKKERKKKEERKKERQKDRQT 228

Query: 78  KEAEEK 83
              E++
Sbjct: 229 NWREKE 234



 Score = 31.6 bits (70), Expect = 0.20
 Identities = 21/74 (28%), Positives = 39/74 (52%), Gaps = 5/74 (6%)

Query: 14  KDMGKMLGGEEEKDPDAQKKEE----ERQEALRQQEEERKAKHARMEAEREKVRQQIRDK 69
           K +G+     +EK+   +KK E    ER++   ++E   + K  + + ER+K RQ+ R +
Sbjct: 169 KQVGEKEEERKEKERKERKKRERNRKERKKERERKERRERKKERKKKEERKKERQKDR-Q 227

Query: 70  YGLKKKEEKEAEEK 83
              ++KE  + E K
Sbjct: 228 TNWREKERGKRERK 241



 Score = 28.9 bits (63), Expect = 1.3
 Identities = 13/56 (23%), Positives = 31/56 (55%)

Query: 28 PDAQKKEEERQEALRQQEEERKAKHARMEAEREKVRQQIRDKYGLKKKEEKEAEEK 83
          P  Q +  ER+  +  ++E +K + +  + ER +  ++ R++   +K+E  + E+K
Sbjct: 32 PGWQSEIREREREIETRKEGKKERESERKKERREREKRKREREKERKRERGKKEKK 87


>gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-like
           [Homo sapiens]
          Length = 828

 Score = 48.9 bits (115), Expect = 1e-06
 Identities = 29/106 (27%), Positives = 57/106 (53%), Gaps = 1/106 (0%)

Query: 14  KDMGKMLGGEEEKDPDAQKKEEERQEALRQQEEERKAKHARMEAEREKVRQQIRDKYGLK 73
           ++  +M+  +EEK  + ++K  E++E +R+QEE+ + +  +M+ + EK+R+Q     G +
Sbjct: 628 QEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKMREQEEKMQGQE 687

Query: 74  KKEEKEAEEKAALEQPCEGSLTRPKKAIPAGCGDEE-EEEEESILD 118
           +K  ++ E+    E+   G   +         G EE  E+EE I D
Sbjct: 688 EKMREQEEKMRGQEEKMWGQEEKMWGQEEKMWGQEEMREKEERIRD 733



 Score = 40.0 bits (92), Expect = 6e-04
 Identities = 23/94 (24%), Positives = 54/94 (57%), Gaps = 3/94 (3%)

Query: 23  EEEKDPDAQKKEEERQEALRQQEEERKAKHARMEAEREKVRQQIRDKYGLKKKEEKEAEE 82
           EEE+  + +KK  E +E +R+QEE+ + +  +M  + EK+ +Q   +  ++++EEK  E+
Sbjct: 558 EEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQ---EEKMQEQEEKMWEQ 614

Query: 83  KAALEQPCEGSLTRPKKAIPAGCGDEEEEEEESI 116
           +  + +  E    + ++ +     ++ +E+EE +
Sbjct: 615 EEKMWEQEEEDKMQEQEEMMWEQEEKMQEQEEKM 648



 Score = 39.7 bits (91), Expect = 7e-04
 Identities = 22/66 (33%), Positives = 39/66 (59%), Gaps = 2/66 (3%)

Query: 23  EEEKDPDAQKKEEERQEALRQQEEERKAKHARMEAEREKVRQQIRDKYGLKKKEEKEAEE 82
           E+EK+   Q+KE   Q+ LR+QEE+ + +  +M  + EK+R+Q    +  +++E    +E
Sbjct: 287 EQEKELREQEKELREQKKLREQEEQMQEQEEKMWEQEEKMREQEEKMW--RQEERLWEQE 344

Query: 83  KAALEQ 88
           K   EQ
Sbjct: 345 KQMREQ 350



 Score = 39.7 bits (91), Expect = 7e-04
 Identities = 18/75 (24%), Positives = 45/75 (60%)

Query: 14  KDMGKMLGGEEEKDPDAQKKEEERQEALRQQEEERKAKHARMEAEREKVRQQIRDKYGLK 73
           ++  K +  EEE   + ++K +E++E +R+QEE+   +  +M+ + EK+ +Q    +  +
Sbjct: 563 REREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEKMWEQE 622

Query: 74  KKEEKEAEEKAALEQ 88
           ++++ + +E+   EQ
Sbjct: 623 EEDKMQEQEEMMWEQ 637



 Score = 38.9 bits (89), Expect = 0.001
 Identities = 23/69 (33%), Positives = 39/69 (56%), Gaps = 3/69 (4%)

Query: 23  EEEKDPDAQKKEEERQEALRQQEEERKAKHARMEAEREKVRQQIR---DKYGLKKKEEKE 79
           EEE+  + +KK  E +E +R+QEE+ + +   M  + EK  QQ R    K  L ++E+ +
Sbjct: 390 EEERIREREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQ 449

Query: 80  AEEKAALEQ 88
            +E+   EQ
Sbjct: 450 EQEEKIWEQ 458



 Score = 38.5 bits (88), Expect = 0.002
 Identities = 25/104 (24%), Positives = 55/104 (52%), Gaps = 3/104 (2%)

Query: 13  TKDMGKMLGGEEEKDPDAQKKEEERQEALRQQEEERKAKHARMEAEREKVRQQ---IRDK 69
           T  + + +  +EE+  + +KK  +++E + +QEE  + +  +M  + EK+R+Q   +R++
Sbjct: 229 TNTLQEEMWRQEEELREQEKKIRKQEEKMWRQEERLREQEGKMREQEEKMRRQEKRLREQ 288

Query: 70  YGLKKKEEKEAEEKAALEQPCEGSLTRPKKAIPAGCGDEEEEEE 113
               +++EKE  E+  L +  E    + +K         E+EE+
Sbjct: 289 EKELREQEKELREQKKLREQEEQMQEQEEKMWEQEEKMREQEEK 332



 Score = 38.5 bits (88), Expect = 0.002
 Identities = 19/69 (27%), Positives = 41/69 (59%), Gaps = 3/69 (4%)

Query: 23  EEEKDPDAQKKEE---ERQEALRQQEEERKAKHARMEAEREKVRQQIRDKYGLKKKEEKE 79
           E+E++   Q++EE   E++E +++QEE+   +  +M  + EK+R+Q     G ++K  ++
Sbjct: 620 EQEEEDKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKMREQ 679

Query: 80  AEEKAALEQ 88
            E+    E+
Sbjct: 680 EEKMQGQEE 688



 Score = 37.7 bits (86), Expect = 0.003
 Identities = 19/61 (31%), Positives = 39/61 (63%), Gaps = 1/61 (1%)

Query: 23  EEEKDPDAQKKEEERQEALRQQEEERKAKHARMEAEREKVRQQIRDKYGLKKKEEKEAEE 82
           E+EK+   QKK  E++E +++QEE+   +  +M  + EK+ +Q  ++   ++K+ +E E+
Sbjct: 294 EQEKELREQKKLREQEEQMQEQEEKMWEQEEKMREQEEKMWRQ-EERLWEQEKQMREQEQ 352

Query: 83  K 83
           K
Sbjct: 353 K 353



 Score = 37.7 bits (86), Expect = 0.003
 Identities = 24/96 (25%), Positives = 53/96 (55%), Gaps = 5/96 (5%)

Query: 23  EEEKDPDAQKKEEERQEALRQQEEERKAKHARMEAEREKVRQQ----IRDKYGLKKKEEK 78
           EE+K  + +KK  +++E +R++E  R+ +  +M  E E +R+Q       +  ++++EEK
Sbjct: 538 EEKKTQEQEKKTWDQEEKMREEERMRE-REKKMREEEEMMREQEEKMQEQEEKMREQEEK 596

Query: 79  EAEEKAALEQPCEGSLTRPKKAIPAGCGDEEEEEEE 114
             E++  +++  E    + +K       D+ +E+EE
Sbjct: 597 MWEQEEKMQEQEEKMWEQEEKMWEQEEEDKMQEQEE 632



 Score = 37.7 bits (86), Expect = 0.003
 Identities = 20/71 (28%), Positives = 45/71 (63%), Gaps = 2/71 (2%)

Query: 13  TKDMGKMLGGEEEKDPDAQKKEEERQEALRQQEEERKAKHARMEAEREKVRQQIRDKYGL 72
           T++  K    +EEK  + +++  ER++ +R++EE  + +  +M+ + EK+R+Q  +K   
Sbjct: 542 TQEQEKKTWDQEEKMRE-EERMREREKKMREEEEMMREQEEKMQEQEEKMREQ-EEKMWE 599

Query: 73  KKKEEKEAEEK 83
           ++++ +E EEK
Sbjct: 600 QEEKMQEQEEK 610



 Score = 37.0 bits (84), Expect = 0.005
 Identities = 24/98 (24%), Positives = 49/98 (50%), Gaps = 1/98 (1%)

Query: 18  KMLGGEEEKDPDAQKKEEERQEALRQQEEERKAKHARMEAEREKVRQQIRDKYGLKKKEE 77
           KM   EE+     +K  E+ ++   Q+EE++  +   M  E+E+  Q+  +K   ++++ 
Sbjct: 596 KMWEQEEKMQEQEEKMWEQEEKMWEQEEEDKMQEQEEMMWEQEEKMQEQEEKMWEQEEKM 655

Query: 78  KEAEEK-AALEQPCEGSLTRPKKAIPAGCGDEEEEEEE 114
           +E EEK    E+  +G   + ++      G EE+  E+
Sbjct: 656 REQEEKMREQEEKMQGQEEKMREQEEKMQGQEEKMREQ 693



 Score = 36.2 bits (82), Expect = 0.008
 Identities = 24/83 (28%), Positives = 47/83 (56%), Gaps = 8/83 (9%)

Query: 14  KDMGKMLGGE-----EEKDPDAQKKEEERQEALRQQEEERKAKHARMEAEREKVR---QQ 65
           +D  +M G E     +EK  + + +  E++E +R QE++   +  RM  + E++R   ++
Sbjct: 463 RDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMWEQDERLREKEER 522

Query: 66  IRDKYGLKKKEEKEAEEKAALEQ 88
           +R++  + ++EEK  EEK   EQ
Sbjct: 523 MREQKKMWQQEEKMREEKKTQEQ 545



 Score = 35.8 bits (81), Expect = 0.011
 Identities = 21/90 (23%), Positives = 48/90 (53%), Gaps = 2/90 (2%)

Query: 23  EEEK--DPDAQKKEEERQEALRQQEEERKAKHARMEAEREKVRQQIRDKYGLKKKEEKEA 80
           +EEK  + + + K +E++E + +QEE+ + +  +M  + EK+R+Q       ++K + + 
Sbjct: 614 QEEKMWEQEEEDKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQE 673

Query: 81  EEKAALEQPCEGSLTRPKKAIPAGCGDEEE 110
           E+    E+  +G   + ++      G EE+
Sbjct: 674 EKMREQEEKMQGQEEKMREQEEKMRGQEEK 703



 Score = 35.4 bits (80), Expect = 0.014
 Identities = 23/82 (28%), Positives = 47/82 (57%), Gaps = 11/82 (13%)

Query: 18  KMLGGEEEKDPDAQKKEEERQEALRQQEEERKAKHARMEAEREKVRQQ---IRDK----- 69
           K L  +EE+  + ++K  E++E +R+QEE+   +  R+  + +++R+Q   +RD+     
Sbjct: 303 KKLREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEERMW 362

Query: 70  ---YGLKKKEEKEAEEKAALEQ 88
                L++KEE+  E++   EQ
Sbjct: 363 EQDERLREKEERMREQEKMWEQ 384



 Score = 35.4 bits (80), Expect = 0.014
 Identities = 20/67 (29%), Positives = 40/67 (59%), Gaps = 1/67 (1%)

Query: 18  KMLGGEEEKDPDAQKKEEERQEALRQQEEERKAKHARMEAEREKV-RQQIRDKYGLKKKE 76
           +M+  +EEK  + ++K  E++E + +QEE+ + +  +M  + EK+  Q+  DK   +++ 
Sbjct: 574 EMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEEDKMQEQEEM 633

Query: 77  EKEAEEK 83
             E EEK
Sbjct: 634 MWEQEEK 640



 Score = 34.3 bits (77), Expect = 0.031
 Identities = 19/71 (26%), Positives = 43/71 (60%), Gaps = 5/71 (7%)

Query: 18  KMLGGEEEKDPDAQKKEEERQEALRQQEEERKAKHARMEAEREKVRQQIRDKYGLKKKEE 77
           K +  +E+K  D +++  E+ E LR ++EER  +  +M  + EK++++ R    ++++E+
Sbjct: 345 KQMREQEQKMRDQEERMWEQDERLR-EKEERMREQEKMWEQEEKMQEEER----IREREK 399

Query: 78  KEAEEKAALEQ 88
           K  EE+  + +
Sbjct: 400 KMREEEETMRE 410



 Score = 34.3 bits (77), Expect = 0.031
 Identities = 16/66 (24%), Positives = 41/66 (62%)

Query: 23  EEEKDPDAQKKEEERQEALRQQEEERKAKHARMEAEREKVRQQIRDKYGLKKKEEKEAEE 82
           +EEK  + ++K  E++E +++QEE+   +  +M  + E+ + Q +++   +++E+ + +E
Sbjct: 586 QEEKMREQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEEDKMQEQEEMMWEQEEKMQEQE 645

Query: 83  KAALEQ 88
           +   EQ
Sbjct: 646 EKMWEQ 651



 Score = 33.9 bits (76), Expect = 0.040
 Identities = 20/78 (25%), Positives = 43/78 (55%), Gaps = 7/78 (8%)

Query: 18  KMLGGEE---EKDPDAQKKEEERQEALRQQEEERKAKHARMEAEREK----VRQQIRDKY 70
           KM   EE   E+D   ++KEE  +E  +  ++E K +  +   E+EK      +++R++ 
Sbjct: 501 KMWDQEERMWEQDERLREKEERMREQKKMWQQEEKMREEKKTQEQEKKTWDQEEKMREEE 560

Query: 71  GLKKKEEKEAEEKAALEQ 88
            ++++E+K  EE+  + +
Sbjct: 561 RMREREKKMREEEEMMRE 578



 Score = 33.9 bits (76), Expect = 0.040
 Identities = 17/77 (22%), Positives = 40/77 (51%)

Query: 14  KDMGKMLGGEEEKDPDAQKKEEERQEALRQQEEERKAKHARMEAEREKVRQQIRDKYGLK 73
           ++  + + G+EEK  + ++K   ++E +  QEE+   +  +M  + E   ++ R +   +
Sbjct: 677 REQEEKMQGQEEKMREQEEKMRGQEEKMWGQEEKMWGQEEKMWGQEEMREKEERIRDQKE 736

Query: 74  KKEEKEAEEKAALEQPC 90
           K +E+  E +    +PC
Sbjct: 737 KMQERLPEHEERCSEPC 753



 Score = 33.5 bits (75), Expect = 0.052
 Identities = 18/66 (27%), Positives = 39/66 (59%), Gaps = 4/66 (6%)

Query: 23  EEEKDPDAQKKEEERQEALRQQEEERKAKHARMEAEREKVRQQIRDKYGLKKKEEKEAEE 82
           +EE+  + +K+  E+++ +R QEE    +  R+  + E++R+Q +    + ++EEK  EE
Sbjct: 336 QEERLWEQEKQMREQEQKMRDQEERMWEQDERLREKEERMREQEK----MWEQEEKMQEE 391

Query: 83  KAALEQ 88
           +   E+
Sbjct: 392 ERIRER 397



 Score = 32.7 bits (73), Expect = 0.089
 Identities = 22/75 (29%), Positives = 40/75 (53%), Gaps = 9/75 (12%)

Query: 23  EEEKDPD-----AQKKEEERQEALRQQEEERKAKHARMEAEREKVRQQIRDKY----GLK 73
           +EEK  D      Q+K+  RQE +R+QE++   +  +M  + +K+  Q    +     L+
Sbjct: 458 QEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMWEQDERLR 517

Query: 74  KKEEKEAEEKAALEQ 88
           +KEE+  E+K   +Q
Sbjct: 518 EKEERMREQKKMWQQ 532



 Score = 32.0 bits (71), Expect = 0.15
 Identities = 19/63 (30%), Positives = 40/63 (63%), Gaps = 6/63 (9%)

Query: 23  EEEKDPDAQKKEEERQEALRQQEEERKAKHARMEAEREKVRQQIRDKYGLKKKEEK--EA 80
           EEE+    Q+++ ++QE    ++EE++ +  R+  ++EK+ +Q +    ++++EEK  E 
Sbjct: 403 EEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEK----MQEQEEKIWEQ 458

Query: 81  EEK 83
           EEK
Sbjct: 459 EEK 461



 Score = 31.6 bits (70), Expect = 0.20
 Identities = 16/69 (23%), Positives = 40/69 (57%), Gaps = 3/69 (4%)

Query: 23  EEEKDPDAQKKEEERQEALRQQEEERKAKHARMEAEREKVRQQIRDKY---GLKKKEEKE 79
           E+E+    +++  ER++ +R++EE  + +  +M+ + E + +Q   ++    L +++EK 
Sbjct: 383 EQEEKMQEEERIREREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKL 442

Query: 80  AEEKAALEQ 88
            E++   EQ
Sbjct: 443 WEQEKMQEQ 451



 Score = 30.8 bits (68), Expect = 0.34
 Identities = 18/78 (23%), Positives = 46/78 (58%), Gaps = 3/78 (3%)

Query: 14  KDMGKMLGGEEEKDPDAQKKEEERQEALRQQEE--ERKAKHARMEAEREKVRQQIRDKYG 71
           ++  + +  +EE+  +  ++  E++E +R+QE+  E++ K    E  RE+ ++   ++  
Sbjct: 348 REQEQKMRDQEERMWEQDERLREKEERMREQEKMWEQEEKMQEEERIREREKKMREEEET 407

Query: 72  LKKKEEK-EAEEKAALEQ 88
           ++++EEK + +E+   EQ
Sbjct: 408 MREQEEKMQKQEENMWEQ 425



 Score = 30.8 bits (68), Expect = 0.34
 Identities = 25/86 (29%), Positives = 42/86 (48%), Gaps = 15/86 (17%)

Query: 18  KMLGGEE---EKDPDAQKKEEE--------RQEALRQQEEERKAKHARMEAEREKVRQQ- 65
           KM   EE   E+D   ++KEE          QE   Q+EE  + +  +M  E E +R+Q 
Sbjct: 353 KMRDQEERMWEQDERLREKEERMREQEKMWEQEEKMQEEERIREREKKMREEEETMREQE 412

Query: 66  ---IRDKYGLKKKEEKEAEEKAALEQ 88
               + +  + ++EEKE +++   EQ
Sbjct: 413 EKMQKQEENMWEQEEKEWQQQRLPEQ 438



 Score = 30.4 bits (67), Expect = 0.44
 Identities = 23/94 (24%), Positives = 51/94 (54%), Gaps = 4/94 (4%)

Query: 23  EEEKDPDAQKKEEERQEALRQQ---EEERKAKHARMEAEREKVRQQIRDKYGLKKKEEKE 79
           E+E+    QKK  +++E +R++   +E+ K    + E  RE+ R + R+K  ++++EE  
Sbjct: 518 EKEERMREQKKMWQQEEKMREEKKTQEQEKKTWDQEEKMREEERMREREK-KMREEEEMM 576

Query: 80  AEEKAALEQPCEGSLTRPKKAIPAGCGDEEEEEE 113
            E++  +++  E    + +K        +E+EE+
Sbjct: 577 REQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEK 610



 Score = 29.6 bits (65), Expect = 0.76
 Identities = 18/58 (31%), Positives = 33/58 (56%), Gaps = 2/58 (3%)

Query: 23  EEEKDPDAQKKEEERQEALRQQEE--ERKAKHARMEAEREKVRQQIRDKYGLKKKEEK 78
           E+EK  + ++K  E++E +R QEE   ++ K  R E  RE+  Q    +  ++ +E+K
Sbjct: 444 EQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQK 501



 Score = 26.6 bits (57), Expect = 6.4
 Identities = 22/75 (29%), Positives = 40/75 (53%), Gaps = 11/75 (14%)

Query: 25  EKDPDAQKKEE-----ERQEALRQQEEERKAK---HARMEAEREKVRQQ---IRDKYGLK 73
           E++   QK+EE     E +E  +Q+  E+K K     +M+ + EK+ +Q   IRD+  + 
Sbjct: 410 EQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMW 469

Query: 74  KKEEKEAEEKAALEQ 88
            +E+K   ++   EQ
Sbjct: 470 GQEKKMWRQEKMREQ 484



 Score = 26.2 bits (56), Expect = 8.4
 Identities = 12/43 (27%), Positives = 20/43 (46%)

Query: 23 EEEKDPDAQKKEEERQEALRQQEEERKAKHARMEAEREKVRQQ 65
          +++K  +    E    E     E+E+KA H   EA R ++  Q
Sbjct: 48 KKKKINNGTNPETTTSEGCHSPEDEKKASHQHQEALRREIEAQ 90


>gi|148746195 trichohyalin [Homo sapiens]
          Length = 1943

 Score = 47.4 bits (111), Expect = 4e-06
 Identities = 23/68 (33%), Positives = 43/68 (63%), Gaps = 2/68 (2%)

Query: 23  EEEKDPDAQKKEEER--QEALRQQEEERKAKHARMEAEREKVRQQIRDKYGLKKKEEKEA 80
           EE ++   ++++EER  Q+  R+QEEER+ +  R E E E+  QQ+R +  L+++++   
Sbjct: 332 EERREQQLRREQEERREQQLRREQEEERREQQLRREQEEERREQQLRREQQLRREQQLRR 391

Query: 81  EEKAALEQ 88
           E++   EQ
Sbjct: 392 EQQLRREQ 399



 Score = 45.4 bits (106), Expect = 1e-05
 Identities = 23/73 (31%), Positives = 44/73 (60%), Gaps = 6/73 (8%)

Query: 30  AQKKEEERQEALRQQEEERKAKHARMEAEREKVRQQIRDKYGLKKKEEKEAEEKAALEQP 89
           ++++EE RQ+ LR++++ER+ +  + E E E++ Q+      LK++ E+E  E+   E+ 
Sbjct: 636 SEEQEERRQQQLRREQQERREQRLKREEEEERLEQR------LKREHEEERREQELAEEE 689

Query: 90  CEGSLTRPKKAIP 102
            E +  R K  IP
Sbjct: 690 QEQARERIKSRIP 702



 Score = 43.5 bits (101), Expect = 5e-05
 Identities = 18/69 (26%), Positives = 47/69 (68%), Gaps = 6/69 (8%)

Query: 26  KDPDAQKKEEERQEALRQQEEERKAKHARMEAEREKVRQQIRDKYGLKKKEEK------E 79
           ++ + ++++E R++ LR+++EER+ +  + + E E+++Q++R +  L++++E+      +
Sbjct: 492 EEEERREQQERREQQLRREQEERREQRLKRQEEEERLQQRLRSEQQLRREQEERREQLLK 551

Query: 80  AEEKAALEQ 88
            EE+  LEQ
Sbjct: 552 REEEKRLEQ 560



 Score = 43.1 bits (100), Expect = 7e-05
 Identities = 21/64 (32%), Positives = 40/64 (62%), Gaps = 5/64 (7%)

Query: 25  EKDPDAQKKEEERQEALRQQEEERKAKHARMEAEREKVRQQIRDKYGLKKKEEKEAEEKA 84
           E+    +++EE R++ LR+++EER+ +  R E E E+  QQ+R     +++EE+  E++ 
Sbjct: 323 EQQERREQQEERREQQLRREQEERREQQLRREQEEERREQQLR-----REQEEERREQQL 377

Query: 85  ALEQ 88
             EQ
Sbjct: 378 RREQ 381



 Score = 42.0 bits (97), Expect = 1e-04
 Identities = 33/115 (28%), Positives = 58/115 (50%), Gaps = 5/115 (4%)

Query: 6    KQALGGATKDMGKMLGGEEEKDPDAQKKEEERQEALRQQEEERKAKHAR---MEAEREKV 62
            K AL    +   ++L  EEE+    ++++  RQE  RQ  EE + +      +  EREK 
Sbjct: 892  KPALQEQLRKEQQLLQEEEEELQREEREKRRRQEQERQYREEEQLQQEEEQLLREEREKR 951

Query: 63   RQQIRDKYGLKKKEEKEAEEKAALEQPCEGSLTRPKKAIPAGCGDEEEEEEESIL 117
            R+Q R++   K K+ ++ EE+   E+P +      +K       +E ++EEE +L
Sbjct: 952  RRQERERQYRKDKKLQQKEEQLLGEEPEKRRRQEREKKYRE--EEELQQEEEQLL 1004



 Score = 41.2 bits (95), Expect = 3e-04
 Identities = 25/95 (26%), Positives = 52/95 (54%), Gaps = 3/95 (3%)

Query: 23  EEEKDPDAQKKEEERQEALRQQEEERKAKHARMEAEREKVRQQIRDKYGLKKKEEKEAEE 82
           + E++ +  ++E  +Q+  R QEEER+ +  ++E E E+  QQ R +  L++++E+  E+
Sbjct: 459 KREEETERHEQERRKQQLKRDQEEERRERWLKLE-EEERREQQERREQQLRREQEERREQ 517

Query: 83  KAALEQPCEGSLTRPKKAIPAGCGDEEEEEEESIL 117
           +  L++  E    + +         E+EE  E +L
Sbjct: 518 R--LKRQEEEERLQQRLRSEQQLRREQEERREQLL 550



 Score = 41.2 bits (95), Expect = 3e-04
 Identities = 24/74 (32%), Positives = 44/74 (59%), Gaps = 3/74 (4%)

Query: 18   KMLGGEEEKDPDAQKKEEERQEALRQQEEERKAKHARMEAEREKVRQQIRDKYGLKKKEE 77
            ++LG E EK    +++++ R+E   QQEEE+  +  R +  R++  +Q R K  L+++EE
Sbjct: 972  QLLGEEPEKRRRQEREKKYREEEELQQEEEQLLREEREKRRRQEWERQYRKKDELQQEEE 1031

Query: 78   ---KEAEEKAALEQ 88
               +E  EK  L++
Sbjct: 1032 QLLREEREKRRLQE 1045



 Score = 40.4 bits (93), Expect = 4e-04
 Identities = 27/100 (27%), Positives = 57/100 (57%), Gaps = 9/100 (9%)

Query: 23   EEE---KDPDAQKKEEERQEALRQQEEERKAKHARMEAEREKVRQQIRDKYGLKKKEEKE 79
            EEE   ++   +++ +ER+   R++EE ++ +   +  EREK R+Q  ++   +++E ++
Sbjct: 1089 EEEQLLREEPEKRRRQERERQCREEEELQQEEEQLLREEREKRRRQELERQYREEEEVQQ 1148

Query: 80   AEEKAALEQPCEGSLTRPKKAIPAGCGDEEE--EEEESIL 117
             EE+   E+P +    R ++ +     +EEE  +EEE +L
Sbjct: 1149 EEEQLLREEPEK----RRRQELERQYREEEELQQEEEQLL 1184



 Score = 40.0 bits (92), Expect = 6e-04
 Identities = 22/66 (33%), Positives = 39/66 (59%), Gaps = 1/66 (1%)

Query: 18  KMLGGEEEKDPDAQKKEEERQEALRQQEEERKAKHARMEAEREKVRQQIRDKYGLKKKEE 77
           + L  E+E++   QK E+ER+E   ++E+E +    + E E E+  +Q R K  LK+ +E
Sbjct: 423 QQLRREQEEERHEQKHEQERREQRLKREQEERRDWLKREEETER-HEQERRKQQLKRDQE 481

Query: 78  KEAEEK 83
           +E  E+
Sbjct: 482 EERRER 487



 Score = 39.7 bits (91), Expect = 7e-04
 Identities = 23/95 (24%), Positives = 55/95 (57%), Gaps = 7/95 (7%)

Query: 23  EEEKDPDAQKKEEERQEALRQQEEERKAKHARMEAEREKVRQQIRDKYGLKKKEEKEAEE 82
           +E ++   ++++EER++ L ++EEER+ +  + E E E++ Q+++ +   + ++E+  E+
Sbjct: 560 QERREQRLKREQEERRDQLLKREEERRQQRLKREQE-ERLEQRLKREEVERLEQEERREQ 618

Query: 83  KAALEQPCEGSLTRPKKAIPAGCGDEEEEEEESIL 117
           +   E+P E    +  K+      +E+EE  +  L
Sbjct: 619 RLKREEPEEERRQQLLKS------EEQEERRQQQL 647



 Score = 39.7 bits (91), Expect = 7e-04
 Identities = 31/102 (30%), Positives = 55/102 (53%), Gaps = 8/102 (7%)

Query: 23   EEEKDPDAQKKEEERQEALRQQEEERKAKHARMEAEREKVRQQIRDKYGLKKKEEKEAEE 82
            EE +  + Q   EER++  RQ+ E +  K   ++ E E++ ++ R+K  L+++E +  EE
Sbjct: 994  EELQQEEEQLLREEREKRRRQEWERQYRKKDELQQEEEQLLREEREKRRLQERERQYREE 1053

Query: 83   KAALEQPCEGSL-----TRPKKAIPAGCGDEEE--EEEESIL 117
            +  L+Q  E  L     TR ++ +      EEE  +EEE +L
Sbjct: 1054 E-ELQQEEEQLLGEERETRRRQELERQYRKEEELQQEEEQLL 1094



 Score = 39.7 bits (91), Expect = 7e-04
 Identities = 31/102 (30%), Positives = 52/102 (50%), Gaps = 11/102 (10%)

Query: 18   KMLGGEEEKDPDAQKKEEERQEALRQQEEERKAKHARMEAEREKVRQQIRDKYGLKKKEE 77
            ++L  E EK    +++ + R+E   QQEEE+     R    R+++ +Q R      K+EE
Sbjct: 1032 QLLREEREKRRLQERERQYREEEELQQEEEQLLGEERETRRRQELERQYR------KEEE 1085

Query: 78   KEAEEKAALEQPCEGSLTRPKKAIPAGCGDEEE--EEEESIL 117
             + EE+  L +  E    R ++     C +EEE  +EEE +L
Sbjct: 1086 LQQEEEQLLREEPE---KRRRQERERQCREEEELQQEEEQLL 1124



 Score = 39.3 bits (90), Expect = 0.001
 Identities = 23/94 (24%), Positives = 49/94 (52%), Gaps = 7/94 (7%)

Query: 24  EEKDPDAQKKEEERQEALRQQEEERKAKHARMEAEREKVRQQIRDKYGLKKKEEKEAEEK 83
           +E++   Q+   E+Q   +Q+EE R+ +  R E +  + +Q+ R +  L++++E+  E++
Sbjct: 291 QEEEQQQQRLRREQQLRRKQEEERREQQEERREQQERREQQEERREQQLRREQEERREQQ 350

Query: 84  AALEQPCEGSLTRPKKAIPAGCGDEEEEEEESIL 117
              EQ  E    + ++       ++EEE  E  L
Sbjct: 351 LRREQEEERREQQLRR-------EQEEERREQQL 377



 Score = 38.9 bits (89), Expect = 0.001
 Identities = 24/86 (27%), Positives = 50/86 (58%), Gaps = 4/86 (4%)

Query: 31  QKKEEERQEALRQQEEERKAKHARMEAEREKVRQQIRDKYGLKKKEEKEAEEKAALEQPC 90
           ++++EER+E L ++EEE++ +  R E   ++ +++ RD+  L K+EE+  +++   EQ  
Sbjct: 539 RREQEERREQLLKREEEKRLEQERREQRLKREQEERRDQ--LLKREEERRQQRLKREQ-- 594

Query: 91  EGSLTRPKKAIPAGCGDEEEEEEESI 116
           E  L +  K       ++EE  E+ +
Sbjct: 595 EERLEQRLKREEVERLEQEERREQRL 620



 Score = 38.5 bits (88), Expect = 0.002
 Identities = 20/63 (31%), Positives = 41/63 (65%), Gaps = 3/63 (4%)

Query: 23  EEEKDPDAQKKEEERQE--ALRQQEEERKAKHARMEAEREKVRQQIRDKYGLKKKEEKEA 80
           +E ++   ++++EER+E    RQ+EEER  +  R E +  + +++ R++  LK++EEK  
Sbjct: 500 QERREQQLRREQEERREQRLKRQEEEERLQQRLRSEQQLRREQEERREQL-LKREEEKRL 558

Query: 81  EEK 83
           E++
Sbjct: 559 EQE 561



 Score = 38.5 bits (88), Expect = 0.002
 Identities = 30/97 (30%), Positives = 52/97 (53%), Gaps = 7/97 (7%)

Query: 23  EEEKDPDAQKKEEE-RQEALRQQEEERKAKHARMEAEREKVRQQIRDKYGLKKKEEKEAE 81
           +EE+     K+EEE RQ+ L++++EER  +  + E E E++ Q+ R +  LK++E +E  
Sbjct: 571 QEERRDQLLKREEERRQQRLKREQEERLEQRLKRE-EVERLEQEERREQRLKREEPEEER 629

Query: 82  EKAAL-----EQPCEGSLTRPKKAIPAGCGDEEEEEE 113
            +  L     E+  +  L R ++         EEEEE
Sbjct: 630 RQQLLKSEEQEERRQQQLRREQQERREQRLKREEEEE 666



 Score = 38.5 bits (88), Expect = 0.002
 Identities = 23/109 (21%), Positives = 57/109 (52%), Gaps = 15/109 (13%)

Query: 14   KDMGKMLGGEEEKDPDAQKKE--------EERQEALRQQEEERKAKHARMEAEREKVRQQ 65
            +D+  +LG ++E+D + +++          E ++  R++++E K +  + + E++ +R++
Sbjct: 1265 QDLQHLLGEQQERDREQERRRWQQRDRHFPEEEQLEREEQKEAKRRDRKSQEEKQLLREE 1324

Query: 66   IRDKYGLKKKEEKEAEEKAALEQPCEGSLTRPKKAIPAGCGDEEEEEEE 114
              +K   ++ + K  EE+  L++  E  L R ++       D +  EEE
Sbjct: 1325 REEKRRRQETDRKFREEEQLLQEREEQPLRRQER-------DRKFREEE 1366



 Score = 38.1 bits (87), Expect = 0.002
 Identities = 22/71 (30%), Positives = 42/71 (59%), Gaps = 6/71 (8%)

Query: 18  KMLGGEEEKDPDAQKKEEERQEALRQQEEERKAKHARMEAEREKVRQQIRDKYGLKKKEE 77
           + L  ++E++   Q++E   Q+  R+Q+EER+ +  R E E E+  QQ+R     +++EE
Sbjct: 304 QQLRRKQEEERREQQEERREQQERREQQEERREQQLRREQE-ERREQQLR-----REQEE 357

Query: 78  KEAEEKAALEQ 88
           +  E++   EQ
Sbjct: 358 ERREQQLRREQ 368



 Score = 37.4 bits (85), Expect = 0.004
 Identities = 25/94 (26%), Positives = 52/94 (55%), Gaps = 6/94 (6%)

Query: 24  EEKDPDAQKKEEERQEALRQQEEERKAKHARMEAEREKVRQQIRDKYGLKKKEEKEAEEK 83
           EE++   Q++  E+Q   R+QEE R+ +  R E E E+++Q++R +  L++++E+  E+ 
Sbjct: 492 EEEERREQQERREQQLR-REQEERREQRLKRQE-EEERLQQRLRSEQQLRREQEERREQL 549

Query: 84  AALEQPCEGSLTRPKKAIPAGCGDEEEEEEESIL 117
              E+       R ++ +      E+EE  + +L
Sbjct: 550 LKREEEKRLEQERREQRLKR----EQEERRDQLL 579



 Score = 37.0 bits (84), Expect = 0.005
 Identities = 16/66 (24%), Positives = 42/66 (63%)

Query: 23  EEEKDPDAQKKEEERQEALRQQEEERKAKHARMEAEREKVRQQIRDKYGLKKKEEKEAEE 82
           +E ++   ++++EER++ L+++EE  + +  R + + ++ +++ R +  LK +EE+  E+
Sbjct: 440 QERREQRLKREQEERRDWLKREEETERHEQERRKQQLKRDQEEERRERWLKLEEEERREQ 499

Query: 83  KAALEQ 88
           +   EQ
Sbjct: 500 QERREQ 505



 Score = 36.6 bits (83), Expect = 0.006
 Identities = 21/69 (30%), Positives = 43/69 (62%), Gaps = 4/69 (5%)

Query: 23  EEEKDPDAQKKEEE--RQEALR-QQEEERKAKHARMEAEREKVRQQIRDKYGLKKKEEKE 79
           EE ++   ++++EE  R++ LR +QEEER+ +  R E +  +  QQ+R +  L+++++  
Sbjct: 344 EERREQQLRREQEEERREQQLRREQEEERREQQLRREQQLRR-EQQLRREQQLRREQQLR 402

Query: 80  AEEKAALEQ 88
            E++   EQ
Sbjct: 403 REQQLRREQ 411



 Score = 35.8 bits (81), Expect = 0.011
 Identities = 24/103 (23%), Positives = 56/103 (54%), Gaps = 4/103 (3%)

Query: 24  EEKDPDAQKKEEERQEALRQQE--EERKAKHARMEAEREKVRQQIRDKYGLKKKEE-KEA 80
           + ++ +  ++EE R++ L+++E  EER+ +  + E + E+ +QQ+R +   ++++  K  
Sbjct: 603 KREEVERLEQEERREQRLKREEPEEERRQQLLKSEEQEERRQQQLRREQQERREQRLKRE 662

Query: 81  EEKAALEQPCEGSLTRPKKAIPAGCGDEEEEEEESILDTVLKY 123
           EE+  LEQ  +      ++       +E+E+  E I   + K+
Sbjct: 663 EEEERLEQRLKREHEEERREQEL-AEEEQEQARERIKSRIPKW 704



 Score = 35.8 bits (81), Expect = 0.011
 Identities = 31/102 (30%), Positives = 54/102 (52%), Gaps = 11/102 (10%)

Query: 18   KMLGGEEEKDPDAQKKEEERQEALRQQEEERKAKHARMEAEREKVRQQIRDKYGLKKKEE 77
            ++LG E E     + + + R+E   QQEEE+      +  E EK R+Q R++   +++EE
Sbjct: 1062 QLLGEERETRRRQELERQYRKEEELQQEEEQ-----LLREEPEKRRRQERERQ-CREEEE 1115

Query: 78   KEAEEKAALEQPCEGSLTRPKKAIPAGCGDEEE--EEEESIL 117
             + EE+  L +  E    R ++ +     +EEE  +EEE +L
Sbjct: 1116 LQQEEEQLLREERE---KRRRQELERQYREEEEVQQEEEQLL 1154



 Score = 35.8 bits (81), Expect = 0.011
 Identities = 20/62 (32%), Positives = 39/62 (62%), Gaps = 6/62 (9%)

Query: 22   GEEEK----DPDAQKKEEERQEALRQQEEERKAKHARMEAEREKVRQQIRDKYGLKKKEE 77
            GEE++    + D + +EEE+Q  LR+QE ERK      +  R+++ ++ R++  L+++ E
Sbjct: 1679 GEEQQLRRQERDRKFREEEQQ--LRRQERERKFLQEEQQLRRQELERKFREEEQLRQETE 1736

Query: 78   KE 79
            +E
Sbjct: 1737 QE 1738



 Score = 35.4 bits (80), Expect = 0.014
 Identities = 29/106 (27%), Positives = 56/106 (52%), Gaps = 8/106 (7%)

Query: 14  KDMGKMLGGEEEKDPDAQKKEE-----ERQEALRQ-QEEERKAKHARMEAEREKVRQQIR 67
           K+  K+   E ++  + Q++EE     ERQE  R+ QEEE++ +  R E +  + +++ R
Sbjct: 255 KEEEKLQEEEPQRQRELQEEEEQLRKLERQELRRERQEEEQQQQRLRREQQLRRKQEEER 314

Query: 68  DKYGLKKKEEKEAEEKAALEQPCEGSLTRPKKAIPAGCGDEEEEEE 113
            +   +++E++E  E+   E+  E  L R ++         E+EEE
Sbjct: 315 REQQEERREQQERREQQ--EERREQQLRREQEERREQQLRREQEEE 358



 Score = 35.0 bits (79), Expect = 0.018
 Identities = 24/97 (24%), Positives = 52/97 (53%), Gaps = 7/97 (7%)

Query: 23  EEEKDPDAQKKEEE--RQEALRQQEEERKAKHARMEAEREKVRQ-----QIRDKYGLKKK 75
           EEE+     ++E++  R++ LR++++ R+ +  R E +  + +Q     Q+R +  L+++
Sbjct: 369 EEERREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRRE 428

Query: 76  EEKEAEEKAALEQPCEGSLTRPKKAIPAGCGDEEEEE 112
           +E+E  E+   ++  E  L R ++        EEE E
Sbjct: 429 QEEERHEQKHEQERREQRLKREQEERRDWLKREEETE 465



 Score = 35.0 bits (79), Expect = 0.018
 Identities = 21/84 (25%), Positives = 39/84 (46%)

Query: 31  QKKEEERQEALRQQEEERKAKHARMEAEREKVRQQIRDKYGLKKKEEKEAEEKAALEQPC 90
           Q+   E+Q    Q+EE  + KH +   E+   R+Q   +  LK++EE E  E+   +Q  
Sbjct: 417 QQLRREQQLRREQEEERHEQKHEQERREQRLKREQEERRDWLKREEETERHEQERRKQQL 476

Query: 91  EGSLTRPKKAIPAGCGDEEEEEEE 114
           +      ++       +EE  E++
Sbjct: 477 KRDQEEERRERWLKLEEEERREQQ 500



 Score = 34.7 bits (78), Expect = 0.024
 Identities = 21/74 (28%), Positives = 42/74 (56%), Gaps = 3/74 (4%)

Query: 18   KMLGGEEEKDPDAQKKEEERQEALRQQEEERKAKHARMEAEREKVRQQIRDKYGLKKKEE 77
            ++L  E EK    + + + R+E   QQEEE+  +    +  R+++ +Q R++  L+++EE
Sbjct: 1122 QLLREEREKRRRQELERQYREEEEVQQEEEQLLREEPEKRRRQELERQYREEEELQQEEE 1181

Query: 78   ---KEAEEKAALEQ 88
               +E +EK   E+
Sbjct: 1182 QLLREEQEKRRQER 1195



 Score = 34.7 bits (78), Expect = 0.024
 Identities = 21/63 (33%), Positives = 37/63 (58%), Gaps = 6/63 (9%)

Query: 29   DAQKKEEERQEALRQQEEERK---AKHARMEAEREKVRQQIRDKYGLKKKEEKEAEEKAA 85
            + Q ++E  QE LR+QE  RK    +  R E E +++R+Q RD+   K +EE++  ++  
Sbjct: 1728 EEQLRQETEQEQLRRQERYRKILEEEQLRPEREEQQLRRQERDR---KFREEEQLRQERE 1784

Query: 86   LEQ 88
             +Q
Sbjct: 1785 EQQ 1787



 Score = 34.3 bits (77), Expect = 0.031
 Identities = 27/103 (26%), Positives = 48/103 (46%), Gaps = 14/103 (13%)

Query: 22  GEEEKDPDAQKKEEERQEALRQQEEE----------RKAKHARMEAEREKVRQQIRDKYG 71
           G EEK    Q++  ERQ+ + Q+EEE          RK +    E E ++ R+   ++  
Sbjct: 222 GREEK----QQQRRERQDRVFQEEEEKEWRKRETVLRKEEEKLQEEEPQRQRELQEEEEQ 277

Query: 72  LKKKEEKEAEEKAALEQPCEGSLTRPKKAIPAGCGDEEEEEEE 114
           L+K E +E   +   E+  +  L R ++       +  E++EE
Sbjct: 278 LRKLERQELRRERQEEEQQQQRLRREQQLRRKQEEERREQQEE 320



 Score = 34.3 bits (77), Expect = 0.031
 Identities = 30/103 (29%), Positives = 53/103 (51%), Gaps = 5/103 (4%)

Query: 18   KMLGGEEEKDPDAQKKEEERQEALRQQEEERKAKHARMEA---EREKVRQQIRDKYGLKK 74
            + L  EEE+    ++++  RQE  RQ  +++K +    +    E EK R+Q R+K   ++
Sbjct: 934  EQLQQEEEQLLREEREKRRRQERERQYRKDKKLQQKEEQLLGEEPEKRRRQEREK-KYRE 992

Query: 75   KEEKEAEEKAALEQPCEGSLTRPKKAIPAGCGDEEEEEEESIL 117
            +EE + EE+  L +  E    R +        DE ++EEE +L
Sbjct: 993  EEELQQEEEQLLREERE-KRRRQEWERQYRKKDELQQEEEQLL 1034



 Score = 34.3 bits (77), Expect = 0.031
 Identities = 20/64 (31%), Positives = 37/64 (57%), Gaps = 4/64 (6%)

Query: 29   DAQKKEEERQEALRQQEEERK---AKHARMEAEREKVRQQIRD-KYGLKKKEEKEAEEKA 84
            + Q ++E  ++ LR QE +RK    +  R E E +++R Q RD KY  ++++ +  E++ 
Sbjct: 1776 EEQLRQEREEQQLRSQESDRKFREEEQLRQEREEQQLRPQQRDGKYRWEEEQLQLEEQEQ 1835

Query: 85   ALEQ 88
             L Q
Sbjct: 1836 RLRQ 1839



 Score = 33.9 bits (76), Expect = 0.040
 Identities = 24/97 (24%), Positives = 51/97 (52%), Gaps = 10/97 (10%)

Query: 23  EEEKDPDAQKKEEERQEALRQQEEERKAKHARMEAEREKVRQQI-RDKYGLKKKEEKEAE 81
           EEE     ++K +E++  L + EE+ + +    + +R++  +++ R +   +++EE+ AE
Sbjct: 130 EEEPGQRRRQKRQEQERELAEGEEQSEKQERLEQRDRQRRDEELWRQRQEWQEREERRAE 189

Query: 82  EKAALEQPCEGSLTRPKKAIPAGCGDEEEEEEESILD 118
           E+    Q C+G  T   +  P    DEE+     +L+
Sbjct: 190 EEQL--QSCKGHET---EEFP----DEEQLRRRELLE 217



 Score = 33.9 bits (76), Expect = 0.040
 Identities = 25/96 (26%), Positives = 46/96 (47%), Gaps = 4/96 (4%)

Query: 23  EEEKDPDAQKKEEERQEALRQQEEERKAKHARMEAEREKVRQQIRDKYGLKKKEEKEAEE 82
           E+ +  + Q+   ERQE  +QQ+  R+ +  R + E E+  QQ   +   +++E++E   
Sbjct: 276 EQLRKLERQELRRERQEEEQQQQRLRREQQLRRKQEEERREQQEERREQQERREQQEERR 335

Query: 83  KAAL----EQPCEGSLTRPKKAIPAGCGDEEEEEEE 114
           +  L    E+  E  L R ++          E+EEE
Sbjct: 336 EQQLRREQEERREQQLRREQEEERREQQLRREQEEE 371



 Score = 33.9 bits (76), Expect = 0.040
 Identities = 24/92 (26%), Positives = 47/92 (51%), Gaps = 9/92 (9%)

Query: 29   DAQKKEEERQEALRQQEEERKAKHARMEAEREKVRQQIRDKYGLKKKEEKEAEEKAALEQ 88
            + Q + E  ++ LR+QE +RK +      E E++RQ+  ++    ++ +++  E+  L Q
Sbjct: 1752 EEQLRPEREEQQLRRQERDRKFR------EEEQLRQEREEQQLRSQESDRKFREEEQLRQ 1805

Query: 89   PCEGSLTRPKKAIPAGCGDEEE---EEEESIL 117
              E    RP++       +EE+   EE+E  L
Sbjct: 1806 EREEQQLRPQQRDGKYRWEEEQLQLEEQEQRL 1837



 Score = 33.5 bits (75), Expect = 0.052
 Identities = 19/92 (20%), Positives = 49/92 (53%), Gaps = 4/92 (4%)

Query: 23  EEEKDPDAQKKEEERQEALRQQEEERKAKHARMEAEREKVRQQIRDKYGLKKKEEKEAEE 82
           +EE++ + +K+E   ++   + +EE   +   ++ E E++R+  R +   +++EE++ ++
Sbjct: 239 QEEEEKEWRKRETVLRKEEEKLQEEEPQRQRELQEEEEQLRKLERQELRRERQEEEQQQQ 298

Query: 83  KAALEQPCEGSLTRPKKAIPAGCGDEEEEEEE 114
           +   EQ     L R ++       +E  E++E
Sbjct: 299 RLRREQ----QLRRKQEEERREQQEERREQQE 326



 Score = 33.5 bits (75), Expect = 0.052
 Identities = 17/66 (25%), Positives = 40/66 (60%), Gaps = 1/66 (1%)

Query: 18  KMLGGEEEKDPDAQKKEEERQEALRQQEEERKAKHARMEAEREKVRQQIRDKYGLKKKEE 77
           ++L  EE+++   Q+   E+QE  R+Q  +R+ +  R+E   ++  ++ R +  L ++E+
Sbjct: 632 QLLKSEEQEERRQQQLRREQQER-REQRLKREEEEERLEQRLKREHEEERREQELAEEEQ 690

Query: 78  KEAEEK 83
           ++A E+
Sbjct: 691 EQARER 696



 Score = 33.5 bits (75), Expect = 0.052
 Identities = 21/67 (31%), Positives = 41/67 (61%), Gaps = 4/67 (5%)

Query: 26  KDPDAQKKEEERQEALRQQEEERKAKHARMEAER--EKVRQQIRDKYGLKKKEEKE--AE 81
           ++ + Q +EEER    +Q+EE+R+    + +AE   E+ RQ++  +  L+++ E++  AE
Sbjct: 742 RESELQWQEEERAHRQQQEEEQRRDFTWQWQAEEKSERGRQRLSARPPLREQRERQLRAE 801

Query: 82  EKAALEQ 88
           E+   EQ
Sbjct: 802 ERQQREQ 808



 Score = 33.5 bits (75), Expect = 0.052
 Identities = 19/70 (27%), Positives = 38/70 (54%), Gaps = 2/70 (2%)

Query: 24  EEKDPDAQKKEEERQEALRQQEEERKAKHARMEAEREKVRQQIRDKYGLKKKEEKE--AE 81
           E+++   + +E +++E     EEE K +  R   EREK  Q + ++  L+++E  +   E
Sbjct: 792 EQRERQLRAEERQQREQRFLPEEEEKEQRRRQRREREKELQFLEEEEQLQRRERAQQLQE 851

Query: 82  EKAALEQPCE 91
           E+  L++  E
Sbjct: 852 EEDGLQEDQE 861



 Score = 33.5 bits (75), Expect = 0.052
 Identities = 19/99 (19%), Positives = 50/99 (50%), Gaps = 6/99 (6%)

Query: 24   EEKDPDAQKKEEERQEALRQQEEERKAKHARMEAEREKVRQQIRDKYGLKKKEEKEAEEK 83
            E +  + ++ ++E ++ LR+++E+R+ +  R   E E++++Q R      K+  ++ +++
Sbjct: 1167 ERQYREEEELQQEEEQLLREEQEKRRQERERQYREEEELQRQKR------KQRYRDEDQR 1220

Query: 84   AALEQPCEGSLTRPKKAIPAGCGDEEEEEEESILDTVLK 122
            + L+   E       +     C   E E+   + D+ L+
Sbjct: 1221 SDLKWQWEPEKENAVRDNKVYCKGRENEQFRQLEDSQLR 1259



 Score = 33.5 bits (75), Expect = 0.052
 Identities = 22/72 (30%), Positives = 42/72 (58%), Gaps = 6/72 (8%)

Query: 23   EEEKDPDAQKKEE---ERQEALRQQEEERKAKHA---RMEAEREKVRQQIRDKYGLKKKE 76
            EEE+    Q++E    + ++ LR+QE ERK +     R E E+E++R+Q R +  L++++
Sbjct: 1695 EEEQQLRRQERERKFLQEEQQLRRQELERKFREEEQLRQETEQEQLRRQERYRKILEEEQ 1754

Query: 77   EKEAEEKAALEQ 88
             +   E+  L +
Sbjct: 1755 LRPEREEQQLRR 1766



 Score = 33.1 bits (74), Expect = 0.069
 Identities = 16/71 (22%), Positives = 40/71 (56%), Gaps = 5/71 (7%)

Query: 23   EEEKDPDAQKKEEER-----QEALRQQEEERKAKHARMEAEREKVRQQIRDKYGLKKKEE 77
            +E ++    ++E +R     ++ +R+QE+ERK      +  R++ +QQ+R +   K +E+
Sbjct: 1565 QEREEQQLSRQERDRKFRLEEQKVRRQEQERKFMEDEQQLRRQEGQQQLRQERDRKFRED 1624

Query: 78   KEAEEKAALEQ 88
            ++  ++   +Q
Sbjct: 1625 EQLLQEREEQQ 1635



 Score = 32.7 bits (73), Expect = 0.089
 Identities = 25/95 (26%), Positives = 43/95 (45%), Gaps = 9/95 (9%)

Query: 23   EEEKDPDAQKKEEERQEALRQQEEERKAKHARMEAEREKVRQQIRDKYGLKKKEEKEAEE 82
            + +   D Q    E+QE  R+QE  R  +  R   E E++ ++  ++   K+++ K  EE
Sbjct: 1260 DRQSQQDLQHLLGEQQERDREQERRRWQQRDRHFPEEEQLERE--EQKEAKRRDRKSQEE 1317

Query: 83   KAALEQPCEGSLTRPKKAIPAGCGDEEEEEEESIL 117
            K  L +  E    R +        D +  EEE +L
Sbjct: 1318 KQLLREEREEKRRRQET-------DRKFREEEQLL 1345



 Score = 32.7 bits (73), Expect = 0.089
 Identities = 26/101 (25%), Positives = 53/101 (52%), Gaps = 11/101 (10%)

Query: 27   DPDAQKKEEER------QEALRQQEEERKAKHARMEAER-EKVRQQIRDKYGLKKKE-EK 78
            D D + +EEE+      ++ LR+QE +RK +    +  R E+ R+ ++++  L+++E E+
Sbjct: 1664 DRDRKFREEEQLLQEGEEQQLRRQERDRKFREEEQQLRRQERERKFLQEEQQLRRQELER 1723

Query: 79   EAEEKAALEQPCEGSLTRPKKAIPAGCGDEE---EEEEESI 116
            +  E+  L Q  E    R ++       +E+   E EE+ +
Sbjct: 1724 KFREEEQLRQETEQEQLRRQERYRKILEEEQLRPEREEQQL 1764



 Score = 32.3 bits (72), Expect = 0.12
 Identities = 24/89 (26%), Positives = 41/89 (46%), Gaps = 12/89 (13%)

Query: 29   DAQKKEEERQEALRQQEEERKAKHARMEAEREKVRQQIRDKYGLKKKEEKEAEEKAALEQ 88
            D Q  +E  ++ L +QE +RK      +  R++  QQ+R       ++ K  EE+  L++
Sbjct: 1624 DEQLLQEREEQQLHRQERDRKFLEEEPQLRRQEREQQLR-----HDRDRKFREEEQLLQE 1678

Query: 89   PCEGSLTRPKKAIPAGCGDEEEEEEESIL 117
              E  L R ++       D +  EEE  L
Sbjct: 1679 GEEQQLRRQER-------DRKFREEEQQL 1700



 Score = 32.0 bits (71), Expect = 0.15
 Identities = 19/68 (27%), Positives = 42/68 (61%), Gaps = 3/68 (4%)

Query: 23  EEEKDPDAQKK-EEERQE-ALRQQEEERKAKHARMEAEREKVRQQIRDKYGLKKKEEKEA 80
           EE ++   +++ EEER+E  LR++++ R+ +  R E +  +  QQ+R +  L+++++   
Sbjct: 357 EERREQQLRREQEEERREQQLRREQQLRREQQLRREQQLRR-EQQLRREQQLRREQQLRR 415

Query: 81  EEKAALEQ 88
           E++   EQ
Sbjct: 416 EQQLRREQ 423



 Score = 31.6 bits (70), Expect = 0.20
 Identities = 22/76 (28%), Positives = 39/76 (51%), Gaps = 2/76 (2%)

Query: 16  MGKMLGGEEEKDPDAQKKEEERQEALRQQEEERKAKHARMEAEREKVRQQIRDKYGLKKK 75
           +G+  G +EEK      KE   Q+  R+QEE+++    R     E+  Q+ R K   +++
Sbjct: 89  LGQATGLDEEKRARCDGKESLLQD--RRQEEDQRRFEPRDRQLEEEPGQRRRQKRQEQER 146

Query: 76  EEKEAEEKAALEQPCE 91
           E  E EE++  ++  E
Sbjct: 147 ELAEGEEQSEKQERLE 162



 Score = 31.6 bits (70), Expect = 0.20
 Identities = 24/101 (23%), Positives = 51/101 (50%), Gaps = 4/101 (3%)

Query: 18  KMLGGEEEKDPDAQKKEEERQEALRQQEEERKAKHARMEAEREKVRQQIRDKYGLKKKEE 77
           + L  E+E++   Q+   E++E  R+Q+  R+ +  R +  R +  QQ+R +  L+++++
Sbjct: 349 QQLRREQEEERREQQLRREQEEERREQQLRREQQLRREQQLRRE--QQLRREQQLRREQQ 406

Query: 78  KEAEEKAALEQPC--EGSLTRPKKAIPAGCGDEEEEEEESI 116
              E++   EQ    E  L R ++        E+E  E+ +
Sbjct: 407 LRREQQLRREQQLRREQQLRREQEEERHEQKHEQERREQRL 447



 Score = 31.6 bits (70), Expect = 0.20
 Identities = 18/77 (23%), Positives = 39/77 (50%), Gaps = 6/77 (7%)

Query: 23  EEEKDPDAQKKEEERQEALRQQEEERKAKHARMEAEREKVRQQIRDKYGLKKKEEKEAEE 82
           EEE+    +++  ER++ L+  EEE + +       RE+ +Q   ++ GL++ +E+   +
Sbjct: 813 EEEEKEQRRRQRREREKELQFLEEEEQLQ------RRERAQQLQEEEDGLQEDQERRRSQ 866

Query: 83  KAALEQPCEGSLTRPKK 99
           +   +Q     L   +K
Sbjct: 867 EQRRDQKWRWQLEEERK 883



 Score = 31.6 bits (70), Expect = 0.20
 Identities = 18/69 (26%), Positives = 36/69 (52%), Gaps = 3/69 (4%)

Query: 23   EEEKDPDAQKKEEERQEALRQQEEERKAKHARM---EAEREKVRQQIRDKYGLKKKEEKE 79
            + +   + Q   EER+E  R+QE +RK +       E E + +R+Q RD+   +++   +
Sbjct: 1311 DRKSQEEKQLLREEREEKRRRQETDRKFREEEQLLQEREEQPLRRQERDRKFREEELRHQ 1370

Query: 80   AEEKAALEQ 88
             + +  LE+
Sbjct: 1371 EQGRKFLEE 1379



 Score = 31.6 bits (70), Expect = 0.20
 Identities = 17/57 (29%), Positives = 30/57 (52%)

Query: 23   EEEKDPDAQKKEEERQEALRQQEEERKAKHARMEAEREKVRQQIRDKYGLKKKEEKE 79
            EE +  +  +K  E ++ LR+QE ERK      +   ++  QQ+R     K +EE++
Sbjct: 1365 EELRHQEQGRKFLEEEQRLRRQERERKFLKEEQQLRCQEREQQLRQDRDRKFREEEQ 1421



 Score = 31.6 bits (70), Expect = 0.20
 Identities = 18/66 (27%), Positives = 38/66 (57%), Gaps = 7/66 (10%)

Query: 21   GGEEEKDPDAQKKEEERQEALRQQEEE----RKAKHARMEAEREKVRQQIRDKYGLKKKE 76
            G +  +D D + +EEE+   LRQ+ EE    R+ +  +   E +KVR+Q +++  ++ ++
Sbjct: 1546 GQQRRQDRDRKFREEEQ---LRQEREEQQLSRQERDRKFRLEEQKVRRQEQERKFMEDEQ 1602

Query: 77   EKEAEE 82
            +   +E
Sbjct: 1603 QLRRQE 1608



 Score = 31.2 bits (69), Expect = 0.26
 Identities = 25/104 (24%), Positives = 50/104 (48%), Gaps = 12/104 (11%)

Query: 23  EEEKDPDAQKKEEERQEALRQQEEERKAKHAR--------MEAEREKV----RQQIRDKY 70
           EEE+    Q++EE+R++   Q + E K++  R        +  +RE+      +Q R++ 
Sbjct: 750 EEERAHRQQQEEEQRRDFTWQWQAEEKSERGRQRLSARPPLREQRERQLRAEERQQREQR 809

Query: 71  GLKKKEEKEAEEKAALEQPCEGSLTRPKKAIPAGCGDEEEEEEE 114
            L ++EEKE   +   E+  E      ++ +      ++ +EEE
Sbjct: 810 FLPEEEEKEQRRRQRREREKELQFLEEEEQLQRRERAQQLQEEE 853



 Score = 31.2 bits (69), Expect = 0.26
 Identities = 23/92 (25%), Positives = 45/92 (48%), Gaps = 6/92 (6%)

Query: 23  EEEKDPDAQKKEEERQEALRQQEEERKAKHARMEAEREKVRQQIRD-KYGLKKKEEKEAE 81
           E EK+    ++EE+ Q   R Q+ + +    + + ER + ++Q RD K+  + +EE++  
Sbjct: 826 EREKELQFLEEEEQLQRRERAQQLQEEEDGLQEDQERRRSQEQRRDQKWRWQLEEERKRR 885

Query: 82  EKAALEQPCEGSLTRPKKAIPAGCGDEEEEEE 113
                 +P      R ++ +      +EEEEE
Sbjct: 886 RHTLYAKPALQEQLRKEQQLL-----QEEEEE 912



 Score = 31.2 bits (69), Expect = 0.26
 Identities = 21/73 (28%), Positives = 39/73 (53%), Gaps = 6/73 (8%)

Query: 23   EEEKDPDAQKKEEERQEALRQQEEERKAKHARMEAEREKV----RQQIRDKYGLKKKEEK 78
            EEE+    ++++  RQE  RQ  EE + +    +  RE+     RQ++  +Y  +++EE 
Sbjct: 1119 EEEQLLREEREKRRRQELERQYREEEEVQQEEEQLLREEPEKRRRQELERQY--REEEEL 1176

Query: 79   EAEEKAALEQPCE 91
            + EE+  L +  E
Sbjct: 1177 QQEEEQLLREEQE 1189



 Score = 31.2 bits (69), Expect = 0.26
 Identities = 22/76 (28%), Positives = 43/76 (56%), Gaps = 4/76 (5%)

Query: 26   KDPDAQKKEEERQEALRQQEEERKAKHARMEAER-EKVRQQIRDKYGLK-KKEEKEAEEK 83
            +D D + +EEE+Q  L +QE +RK +    +  R E+ R+ + ++  L+ ++  K  EE+
Sbjct: 1410 QDRDRKFREEEQQ--LSRQERDRKFREEEQQVRRQERERKFLEEEQQLRQERHRKFREEE 1467

Query: 84   AALEQPCEGSLTRPKK 99
              L++  E  L R ++
Sbjct: 1468 QLLQEREEQQLHRQER 1483



 Score = 31.2 bits (69), Expect = 0.26
 Identities = 17/74 (22%), Positives = 41/74 (55%), Gaps = 3/74 (4%)

Query: 18   KMLGGEEEKDPDAQKKEEERQEALRQQEEE---RKAKHARMEAEREKVRQQIRDKYGLKK 74
            K L  E++   +  +K  E ++ L+++EE+   R+ +  +   E +++R+Q RD+   ++
Sbjct: 1447 KFLEEEQQLRQERHRKFREEEQLLQEREEQQLHRQERDRKFLEEEQQLRRQERDRKFREQ 1506

Query: 75   KEEKEAEEKAALEQ 88
            +   +  E+  LE+
Sbjct: 1507 ELRSQEPERKFLEE 1520



 Score = 31.2 bits (69), Expect = 0.26
 Identities = 21/71 (29%), Positives = 39/71 (54%), Gaps = 4/71 (5%)

Query: 23   EEEKDPDAQKKEEERQEALRQQEEERKAKHARMEAEREKVRQQIRD-KYGLKKKEEKEAE 81
            EE+  P+ ++++  RQE  R+  EE   +  R E E +++R Q  D K+  +++  +E E
Sbjct: 1752 EEQLRPEREEQQLRRQERDRKFREE---EQLRQEREEQQLRSQESDRKFREEEQLRQERE 1808

Query: 82   EKAALEQPCEG 92
            E+    Q  +G
Sbjct: 1809 EQQLRPQQRDG 1819



 Score = 30.8 bits (68), Expect = 0.34
 Identities = 18/71 (25%), Positives = 38/71 (53%), Gaps = 4/71 (5%)

Query: 18  KMLGGEEEKDPDAQKKEEERQEALRQQEEERKAKHARMEAEREKVRQQIRDKYGLKKKEE 77
           + L  E+E+  + + K +E +E L+Q    R     ++  E+E+ R+Q+  +   K+ E+
Sbjct: 505 QQLRREQEERREQRLKRQEEEERLQQ----RLRSEQQLRREQEERREQLLKREEEKRLEQ 560

Query: 78  KEAEEKAALEQ 88
           +  E++   EQ
Sbjct: 561 ERREQRLKREQ 571



 Score = 30.8 bits (68), Expect = 0.34
 Identities = 16/60 (26%), Positives = 35/60 (58%), Gaps = 3/60 (5%)

Query: 23   EEEKDPDAQKKEE---ERQEALRQQEEERKAKHARMEAEREKVRQQIRDKYGLKKKEEKE 79
            EEE+    Q+++    E ++ +R+QE ERK      +  +E+ R+   ++  L+++EE++
Sbjct: 1418 EEEQQLSRQERDRKFREEEQQVRRQERERKFLEEEQQLRQERHRKFREEEQLLQEREEQQ 1477



 Score = 30.8 bits (68), Expect = 0.34
 Identities = 22/89 (24%), Positives = 45/89 (50%), Gaps = 12/89 (13%)

Query: 23   EEEKDPDAQKKEEE-RQEALRQQEEERK-----------AKHARMEAEREKVRQQIRDKY 70
            EEE+    Q+++ + R++ LR QE ERK            +  +   E +++R+Q R + 
Sbjct: 1489 EEEQQLRRQERDRKFREQELRSQEPERKFLEEEQQLHRQQRQRKFLQEEQQLRRQERGQQ 1548

Query: 71   GLKKKEEKEAEEKAALEQPCEGSLTRPKK 99
              + ++ K  EE+   ++  E  L+R ++
Sbjct: 1549 RRQDRDRKFREEEQLRQEREEQQLSRQER 1577



 Score = 30.8 bits (68), Expect = 0.34
 Identities = 13/59 (22%), Positives = 35/59 (59%)

Query: 25   EKDPDAQKKEEERQEALRQQEEERKAKHARMEAEREKVRQQIRDKYGLKKKEEKEAEEK 83
            E++P  +++E E+Q    +  + R+ +    E E +++R+Q RD+   +++++   +E+
Sbjct: 1647 EEEPQLRRQEREQQLRHDRDRKFREEEQLLQEGEEQQLRRQERDRKFREEEQQLRRQER 1705



 Score = 30.4 bits (67), Expect = 0.44
 Identities = 20/93 (21%), Positives = 45/93 (48%), Gaps = 4/93 (4%)

Query: 23   EEEKDPDAQKKEEERQEALRQQEEERKAKHARMEAEREKVRQQIRDKYGLKKKEEKEAEE 82
            E E+ P    + +ER    R++E   + +  +   E +++R+Q R++  LK++++   +E
Sbjct: 1347 EREEQP---LRRQERDRKFREEELRHQEQGRKFLEEEQRLRRQERERKFLKEEQQLRCQE 1403

Query: 83   K-AALEQPCEGSLTRPKKAIPAGCGDEEEEEEE 114
            +   L Q  +      ++ +     D +  EEE
Sbjct: 1404 REQQLRQDRDRKFREEEQQLSRQERDRKFREEE 1436



 Score = 30.0 bits (66), Expect = 0.58
 Identities = 18/66 (27%), Positives = 39/66 (59%), Gaps = 7/66 (10%)

Query: 23  EEEKDPDAQKKEEERQEALRQQEEERKAKHARMEAEREKVRQQIRDKYGLKKKEEKEAEE 82
           +EE+     K+EEE++      E+ER+ +  R++ E+E+ R Q+  +   ++++  + E+
Sbjct: 542 QEERREQLLKREEEKR-----LEQERREQ--RLKREQEERRDQLLKREEERRQQRLKREQ 594

Query: 83  KAALEQ 88
           +  LEQ
Sbjct: 595 EERLEQ 600



 Score = 29.6 bits (65), Expect = 0.76
 Identities = 14/63 (22%), Positives = 37/63 (58%), Gaps = 3/63 (4%)

Query: 23   EEEKDPDAQKKEEERQEALRQQEEE---RKAKHARMEAEREKVRQQIRDKYGLKKKEEKE 79
            E++   D  +K  E ++ L++ EE+   R+ +  +   E +++R+Q R++  L+++++  
Sbjct: 1658 EQQLRHDRDRKFREEEQLLQEGEEQQLRRQERDRKFREEEQQLRRQERERKFLQEEQQLR 1717

Query: 80   AEE 82
             +E
Sbjct: 1718 RQE 1720



 Score = 29.6 bits (65), Expect = 0.76
 Identities = 19/84 (22%), Positives = 42/84 (50%), Gaps = 6/84 (7%)

Query: 33   KEEERQEALRQQEEERKAKHARMEAEREKVRQQIRDKYGLKKKEEKEAEEKAALEQPCEG 92
            +EEE+     +QE+ R+ +  R   E E++R +  ++   +++ +++  E+  L Q  E 
Sbjct: 1726 REEEQLRQETEQEQLRRQERYRKILEEEQLRPEREEQQLRRQERDRKFREEEQLRQEREE 1785

Query: 93   SLTRPKKAIPAGCGDEEEEEEESI 116
               R +++      D +  EEE +
Sbjct: 1786 QQLRSQES------DRKFREEEQL 1803



 Score = 29.3 bits (64), Expect = 0.99
 Identities = 17/61 (27%), Positives = 38/61 (62%), Gaps = 3/61 (4%)

Query: 25  EKDPDAQKKEEER--QEALRQQEEERKAKHARMEAEREKVRQQIRDKYGLKKKEEKEAEE 82
           ++D + ++ +E+R  Q+   Q EEERK +   + A +  +++Q+R +  L ++EE+E + 
Sbjct: 857 QEDQERRRSQEQRRDQKWRWQLEEERKRRRHTLYA-KPALQEQLRKEQQLLQEEEEELQR 915

Query: 83  K 83
           +
Sbjct: 916 E 916



 Score = 28.9 bits (63), Expect = 1.3
 Identities = 14/59 (23%), Positives = 34/59 (57%), Gaps = 2/59 (3%)

Query: 27   DPDAQKKEEERQEALRQQEEE--RKAKHARMEAEREKVRQQIRDKYGLKKKEEKEAEEK 83
            + + Q + +E Q+ LRQ+ +   R+ +    E E +++ +Q RD+  L+++ +   +E+
Sbjct: 1599 EDEQQLRRQEGQQQLRQERDRKFREDEQLLQEREEQQLHRQERDRKFLEEEPQLRRQER 1657



 Score = 28.5 bits (62), Expect = 1.7
 Identities = 18/77 (23%), Positives = 38/77 (49%), Gaps = 2/77 (2%)

Query: 18   KMLGGEEEKDPDAQ--KKEEERQEALRQQEEERKAKHARMEAEREKVRQQIRDKYGLKKK 75
            + L  EE+K+   +  K +EE+Q    ++EE+R+ +    +   E+   Q R++  L+++
Sbjct: 1297 EQLEREEQKEAKRRDRKSQEEKQLLREEREEKRRRQETDRKFREEEQLLQEREEQPLRRQ 1356

Query: 76   EEKEAEEKAALEQPCEG 92
            E      +  L    +G
Sbjct: 1357 ERDRKFREEELRHQEQG 1373



 Score = 28.5 bits (62), Expect = 1.7
 Identities = 17/60 (28%), Positives = 29/60 (48%)

Query: 24   EEKDPDAQKKEEERQEALRQQEEERKAKHARMEAEREKVRQQIRDKYGLKKKEEKEAEEK 83
            EE+    +K   E QE  +++E++R+ +  R   E    RQQ  ++   +  E K  E K
Sbjct: 1848 EEQFATQEKSRREEQELWQEEEQKRRQERERKLREEHIRRQQKEEQRHRQVGEIKSQEGK 1907



 Score = 28.1 bits (61), Expect = 2.2
 Identities = 19/69 (27%), Positives = 36/69 (52%), Gaps = 3/69 (4%)

Query: 23   EEEKDPDAQKKEEE---RQEALRQQEEERKAKHARMEAEREKVRQQIRDKYGLKKKEEKE 79
            EEE+    Q++E +    ++ LR QE E++ +  R    RE+ +Q  R +   K +EE++
Sbjct: 1378 EEEQRLRRQERERKFLKEEQQLRCQEREQQLRQDRDRKFREEEQQLSRQERDRKFREEEQ 1437

Query: 80   AEEKAALEQ 88
               +   E+
Sbjct: 1438 QVRRQERER 1446



 Score = 27.7 bits (60), Expect = 2.9
 Identities = 22/112 (19%), Positives = 53/112 (47%), Gaps = 3/112 (2%)

Query: 23   EEEKDPDAQKKEEERQEALRQQEEERKAKHARMEAEREKVRQQIRDKYGLKKKEEKEAEE 82
            EE +  + Q   EE ++  RQ+ E +  +   ++ E E++ ++ ++K   +++ E++  E
Sbjct: 1144 EEVQQEEEQLLREEPEKRRRQELERQYREEEELQQEEEQLLREEQEK--RRQERERQYRE 1201

Query: 83   KAALEQPCEGSLTRPKKAIPAGCGDEEEEEEESILDTVLKYLPGPLQDMFKK 134
            +  L++       R +          E E+E ++ D  + Y  G   + F++
Sbjct: 1202 EEELQRQKRKQRYRDEDQRSDLKWQWEPEKENAVRDNKV-YCKGRENEQFRQ 1252



 Score = 27.3 bits (59), Expect = 3.8
 Identities = 17/59 (28%), Positives = 32/59 (54%), Gaps = 3/59 (5%)

Query: 23   EEEKDPDAQKKEEERQEALRQQEEERKAKHARMEAEREKVRQQIRDKYGLKKKEEKEAE 81
            EEE   + ++   E  E  R+QE ER+    R E E ++  +Q+  +   K+++E+E +
Sbjct: 1143 EEEVQQEEEQLLREEPEKRRRQELERQ---YREEEELQQEEEQLLREEQEKRRQERERQ 1198



 Score = 26.6 bits (57), Expect = 6.4
 Identities = 14/60 (23%), Positives = 36/60 (60%), Gaps = 1/60 (1%)

Query: 29   DAQKKEEERQEALRQQEEERKAKHARMEAEREKVRQQIRDKYGLKKKEEKEAEEKAALEQ 88
            + Q + EE+++ LR QE +R+ +     A +EK R++ ++ +  ++++ ++  E+   E+
Sbjct: 1825 EEQLQLEEQEQRLR-QERDRQYRAEEQFATQEKSRREEQELWQEEEQKRRQERERKLREE 1883



 Score = 26.2 bits (56), Expect = 8.4
 Identities = 20/71 (28%), Positives = 40/71 (56%), Gaps = 9/71 (12%)

Query: 23   EEEKDPDAQKKEE---ERQEALRQQE--EERKAKHARMEAEREKVRQQIRDKYGLKKKEE 77
            EEE+    Q+++    + ++ LR+QE  ++R+    R   E E++RQ+ R++  L ++E 
Sbjct: 1519 EEEQQLHRQQRQRKFLQEEQQLRRQERGQQRRQDRDRKFREEEQLRQE-REEQQLSRQER 1577

Query: 78   KEAEEKAALEQ 88
               + K  LE+
Sbjct: 1578 ---DRKFRLEE 1585



 Score = 26.2 bits (56), Expect = 8.4
 Identities = 16/62 (25%), Positives = 37/62 (59%), Gaps = 4/62 (6%)

Query: 23   EEEKDPDAQKKEEERQEALRQQEEERKAKHARMEAEREKVRQQIRD-KYGLKKKEEKEAE 81
            EE++    ++ ++ RQ+  R+  EE   +  R E E +++ +Q RD K+ L++++ +  E
Sbjct: 1536 EEQQLRRQERGQQRRQDRDRKFREE---EQLRQEREEQQLSRQERDRKFRLEEQKVRRQE 1592

Query: 82   EK 83
            ++
Sbjct: 1593 QE 1594


>gi|22758136 MAP7 domain containing 2 [Homo sapiens]
          Length = 732

 Score = 47.4 bits (111), Expect = 4e-06
 Identities = 26/80 (32%), Positives = 52/80 (65%), Gaps = 6/80 (7%)

Query: 23  EEEK---DPDAQKKEEERQEALRQQEEERKAKHARMEAEREKVRQQIRDKYGLKKKEEKE 79
           EEE+   + +A+K+EEER+   RQ+EE++K +        E+ +++  ++  LK+K+E+E
Sbjct: 441 EEERLRLEEEARKQEEERK---RQEEEKKKQEGEEKRKAGEEAKRKAEEELLLKEKQEQE 497

Query: 80  AEEKAALEQPCEGSLTRPKK 99
            +EKA +E+  E + T+ ++
Sbjct: 498 KQEKAMIEKQKEAAETKARE 517



 Score = 40.8 bits (94), Expect = 3e-04
 Identities = 22/95 (23%), Positives = 56/95 (58%), Gaps = 3/95 (3%)

Query: 24  EEKDPDAQKKEEERQEALRQQEEERKAKHARMEAEREKVRQQIRDKYGLKKKEEKEAEEK 83
           +++  + ++ E+E Q+ L ++E +RKA+  R+  E E  +Q+   K   ++K+++E EEK
Sbjct: 414 QKEQEEQERVEKEEQDRLEREELKRKAEEERLRLEEEARKQEEERKRQEEEKKKQEGEEK 473

Query: 84  AALEQPCEGSLTRPKKAIPAGCGDEEEEEEESILD 118
               +  E +  + ++ +      E+E++E+++++
Sbjct: 474 ---RKAGEEAKRKAEEELLLKEKQEQEKQEKAMIE 505



 Score = 33.9 bits (76), Expect = 0.040
 Identities = 30/117 (25%), Positives = 59/117 (50%), Gaps = 9/117 (7%)

Query: 8   ALGGATKD---MGKMLGGEEEKDPDAQKKEEERQEAL---RQQEEERKAKHARMEAEREK 61
           A GG  ++   +GK   G  +    A+   E+R++A     Q+E+ER  K  +   ERE+
Sbjct: 376 AAGGKAENSAALGKPTAGTTDAGEAAKILAEKRRQARLQKEQEEQERVEKEEQDRLEREE 435

Query: 62  VRQQIRD-KYGLKKKEEKEAEEKAALEQPCEGSLTRPKKAIPAGCGDEEEEEEESIL 117
           ++++  + +  L+++  K+ EE+   E+  E      ++   AG   + + EEE +L
Sbjct: 436 LKRKAEEERLRLEEEARKQEEERKRQEE--EKKKQEGEEKRKAGEEAKRKAEEELLL 490



 Score = 33.5 bits (75), Expect = 0.052
 Identities = 20/83 (24%), Positives = 51/83 (61%), Gaps = 8/83 (9%)

Query: 24  EEKDPDAQKKEEERQEALRQQEEE--RKAKHARMEAEREKVRQQIRDKY-GLKKKEEKEA 80
           +E+   A+++ EER++ L  +E++   K K AR++ E+     Q+ +++  L+++ ++E 
Sbjct: 52  DERQRLAKERREEREKCLAAREQQILEKQKRARLQYEK-----QMEERWRKLEEQRQRED 106

Query: 81  EEKAALEQPCEGSLTRPKKAIPA 103
           +++AA+E+  +  L   ++ + A
Sbjct: 107 QKRAAVEEKRKQKLREEEERLEA 129



 Score = 33.1 bits (74), Expect = 0.069
 Identities = 28/100 (28%), Positives = 50/100 (50%), Gaps = 13/100 (13%)

Query: 23  EEEKDPDAQKKEEERQEALRQQEEERKAKHARMEAEREKVRQQIRDKYGLKKKEEKEAEE 82
           EE+K  + ++K +  +EA R+ EEE   K        EK  Q+ ++K  ++K  +KEA E
Sbjct: 463 EEKKKQEGEEKRKAGEEAKRKAEEELLLK--------EKQEQEKQEKAMIEK--QKEAAE 512

Query: 83  KAALEQPCEGSLTRPKKAIPAGCGDEEEEEEESILDTVLK 122
             A E   +  L R +  +     ++E  E +  +D ++K
Sbjct: 513 TKAREVAEQMRLEREQIMLQI---EQERLERKKRIDEIMK 549



 Score = 27.3 bits (59), Expect = 3.8
 Identities = 17/52 (32%), Positives = 32/52 (61%), Gaps = 7/52 (13%)

Query: 23  EEEKDPDAQKK---EEERQEALRQQEEERKAKHARMEAEREKVRQ-QIRDKY 70
           EE++  + QK+   EE+R++ LR++EE  +   A M    E+ +Q +++ KY
Sbjct: 99  EEQRQREDQKRAAVEEKRKQKLREEEERLE---AMMRRSLERTQQLELKKKY 147


>gi|31795561 complexin 4 [Homo sapiens]
          Length = 160

 Score = 47.0 bits (110), Expect = 5e-06
 Identities = 40/132 (30%), Positives = 66/132 (50%), Gaps = 17/132 (12%)

Query: 1   MDFVMKQALGGATKDMGKMLGGEEEK------DPDA-----QKKEEERQEALRQQEEERK 49
           M F+MK  +    K++G   G EE K      DP A     +++ EE Q+ + +++ ER 
Sbjct: 1   MAFLMKSMISNQVKNLGFGGGSEENKEEGGASDPAAAQGMTREEYEEYQKQMIEEKMERD 60

Query: 50  AKHARMEAEREKVRQQIRDKYGLKKKEEKEAEEKAALEQPCEGSLTRPKKAIPAGCGDEE 109
           A   + +AER  +R  +R+KY L K E  E + + A +      +  P+        D+E
Sbjct: 61  AAFTQKKAERACLRVHLREKYRLPKSEMDENQIQMAGD-----DVDLPEDLRKMVDEDQE 115

Query: 110 EEEE-ESILDTV 120
           EEE+ +SIL  +
Sbjct: 116 EEEDKDSILGQI 127


>gi|55741709 RNA binding motif protein 25 [Homo sapiens]
          Length = 843

 Score = 45.1 bits (105), Expect = 2e-05
 Identities = 24/76 (31%), Positives = 45/76 (59%), Gaps = 1/76 (1%)

Query: 13  TKDMGKMLGGEEEKDPDAQKKEEERQEALRQQEEERKAKHARMEAEREKVRQQIRDKYGL 72
           + D  K      EK  D +++ E  +E  R++E ER+ +  R E ERE+ R++ +DK   
Sbjct: 374 SSDRNKDRSRSREKSRDRERERERERERERERERERERERER-EREREREREREKDKKRD 432

Query: 73  KKKEEKEAEEKAALEQ 88
           ++++E++A E+  LE+
Sbjct: 433 REEDEEDAYERRKLER 448



 Score = 42.4 bits (98), Expect = 1e-04
 Identities = 29/106 (27%), Positives = 55/106 (51%), Gaps = 12/106 (11%)

Query: 13  TKDMGKMLGGEEEKDPDAQKKEEERQEA---LRQQEEERKAKHARMEAEREKVRQQIRDK 69
           ++++ K     ++ + +  KKE+ERQE     R++E ER+ +  R E ERE+ R++ R+K
Sbjct: 278 SREISKFRDTHKKLEEEKGKKEKERQEIEKERRERERERERERERREREREREREREREK 337

Query: 70  YGLKKKEEKEAEEKAALEQPCEGSLTRPKKAIPAGCGDEEEEEEES 115
              +K+ E+E E     ++  E    R ++       D + + E S
Sbjct: 338 ---EKERERERERDRDRDRTKERDRDRDRER------DRDRDRERS 374



 Score = 40.8 bits (94), Expect = 3e-04
 Identities = 23/91 (25%), Positives = 46/91 (50%)

Query: 23  EEEKDPDAQKKEEERQEALRQQEEERKAKHARMEAEREKVRQQIRDKYGLKKKEEKEAEE 82
           E E++ + +++ E  +E  R++E ER+ +  R + ++    +   D Y  +K E K  E+
Sbjct: 394 EREREREREREREREREREREREREREREREREKDKKRDREEDEEDAYERRKLERKLREK 453

Query: 83  KAALEQPCEGSLTRPKKAIPAGCGDEEEEEE 113
           +AA ++  +    R +K       + E EEE
Sbjct: 454 EAAYQERLKNWEIRERKKTREYEKEAEREEE 484



 Score = 40.0 bits (92), Expect = 6e-04
 Identities = 29/106 (27%), Positives = 53/106 (50%), Gaps = 16/106 (15%)

Query: 18  KMLGGEEEKDPDAQKKEEERQEALRQQEEERKAKHARMEAEREKVRQ-QIRDKYGLKKKE 76
           +M   E ++  + ++ EE RQ  L +   +  A+  RME E E+ RQ QI+ +   +++E
Sbjct: 528 EMEADERDRKREKEELEEIRQRLLAEGHPDPDAELQRMEQEAERRRQPQIKQEPESEEEE 587

Query: 77  EKEAEEKAALEQPCEGSLTRPKKAIPAGCGDEEEEEEESILDTVLK 122
           E++ E++   E+P E               +EEE E++  L   L+
Sbjct: 588 EEKQEKEEKREEPME---------------EEEEPEQKPCLKPTLR 618



 Score = 37.7 bits (86), Expect = 0.003
 Identities = 25/103 (24%), Positives = 52/103 (50%), Gaps = 16/103 (15%)

Query: 13  TKDMGKMLGGEEEKDPDAQKKEEERQEALRQQEEERKAKHARMEAEREKVRQQIRDKYGL 72
           TK+  +    E ++D D ++  +  ++  R +E+ R       + ERE+ R++ R++   
Sbjct: 354 TKERDRDRDRERDRDRDRERSSDRNKDRSRSREKSR-------DRERERERERERER--- 403

Query: 73  KKKEEKEAEEKAALEQPCEGSLTRPKKAIPAGCGDEEEEEEES 115
           +++ E+E E +   E+  E    + KK       D EE+EE++
Sbjct: 404 EREREREREREREREREREREREKDKKR------DREEDEEDA 440



 Score = 37.7 bits (86), Expect = 0.003
 Identities = 26/90 (28%), Positives = 46/90 (51%), Gaps = 8/90 (8%)

Query: 14  KDMGKMLGGEEEKDPDAQKKEEERQEALRQQEEERKAKHARMEAEREKVRQQIRDKYGLK 73
           +++ + L  E   DPDA+ +  E QEA R+++ + K +    E E EK  ++       +
Sbjct: 544 EEIRQRLLAEGHPDPDAELQRME-QEAERRRQPQIKQEPESEEEEEEKQEKE-------E 595

Query: 74  KKEEKEAEEKAALEQPCEGSLTRPKKAIPA 103
           K+EE   EE+   ++PC     RP  + P+
Sbjct: 596 KREEPMEEEEEPEQKPCLKPTLRPISSAPS 625



 Score = 37.0 bits (84), Expect = 0.005
 Identities = 23/77 (29%), Positives = 42/77 (54%), Gaps = 2/77 (2%)

Query: 23  EEEKDPDAQKKEEERQEALRQQEEERKAKHARMEAEREKVRQQIRDKYGLKKKE-EKEAE 81
           + E+  D  K     +E  R +E ER+ +  R E ERE+ R++ R++   +++E E+E +
Sbjct: 370 DRERSSDRNKDRSRSREKSRDRERERERERER-EREREREREREREREREREREREREKD 428

Query: 82  EKAALEQPCEGSLTRPK 98
           +K   E+  E +  R K
Sbjct: 429 KKRDREEDEEDAYERRK 445



 Score = 35.0 bits (79), Expect = 0.018
 Identities = 19/91 (20%), Positives = 47/91 (51%), Gaps = 7/91 (7%)

Query: 23  EEEKDPDAQKKEEERQEALRQQEEERKAKHARMEAEREKVRQQIRDKYGLKKKEEKEAEE 82
           E E++ + +++E ER+    ++ E+ K +    E +R++ R + RD+    ++ +++ + 
Sbjct: 313 ERERERERERREREREREREREREKEKERERERERDRDRDRTKERDR-DRDRERDRDRDR 371

Query: 83  KAALEQPCEGSLTRPKKAIPAGCGDEEEEEE 113
           + + ++  + S +R K        D E E E
Sbjct: 372 ERSSDRNKDRSRSREKSR------DRERERE 396



 Score = 33.9 bits (76), Expect = 0.040
 Identities = 20/86 (23%), Positives = 42/86 (48%)

Query: 14  KDMGKMLGGEEEKDPDAQKKEEERQEALRQQEEERKAKHARMEAEREKVRQQIRDKYGLK 73
           +D   ++  E  K  D  KK EE +    ++ +E + +    E ERE+ R++   +   +
Sbjct: 271 EDKRDLISREISKFRDTHKKLEEEKGKKEKERQEIEKERRERERERERERERRERERERE 330

Query: 74  KKEEKEAEEKAALEQPCEGSLTRPKK 99
           ++ E+E E++   E+  +    R K+
Sbjct: 331 REREREKEKERERERERDRDRDRTKE 356



 Score = 30.4 bits (67), Expect = 0.44
 Identities = 19/92 (20%), Positives = 45/92 (48%), Gaps = 6/92 (6%)

Query: 23  EEEKDPDAQKKEEERQEALRQQEEERKAKHARMEAEREKVRQQIRDKYGLKKKEEKEAEE 82
           E EKD    ++E+E ++A  +++ ERK +      +      +IR+     +K+ +E E+
Sbjct: 424 EREKDKKRDREEDE-EDAYERRKLERKLREKEAAYQERLKNWEIRE-----RKKTREYEK 477

Query: 83  KAALEQPCEGSLTRPKKAIPAGCGDEEEEEEE 114
           +A  E+     + +  K +     D +++ ++
Sbjct: 478 EAEREEERRREMAKEAKRLKEFLEDYDDDRDD 509



 Score = 30.0 bits (66), Expect = 0.58
 Identities = 22/92 (23%), Positives = 47/92 (51%), Gaps = 2/92 (2%)

Query: 23  EEEKDPDAQKKEEERQEALRQQEEERKAKHARMEAEREKVRQQIRDKYGLKKKEEKEAEE 82
           ++++D     +    Q+ LR +E+E +A     + E+E++ ++IR +   +   + +AE 
Sbjct: 504 DDDRDDPKYYRGSALQKRLRDREKEMEADERDRKREKEEL-EEIRQRLLAEGHPDPDAEL 562

Query: 83  KAALEQPCEGSLTRPKKAIPAGCGDEEEEEEE 114
           +  +EQ  E       K  P    +EEE++E+
Sbjct: 563 Q-RMEQEAERRRQPQIKQEPESEEEEEEKQEK 593



 Score = 26.6 bits (57), Expect = 6.4
 Identities = 21/91 (23%), Positives = 45/91 (49%), Gaps = 12/91 (13%)

Query: 25  EKDPDAQKKEEERQEALRQQEEERKAKHARMEAEREKVRQQIRDKYGLKKKEEKEAE-EK 83
           ++D +A + EE++++ + ++  + +  H ++E E+           G K+KE +E E E+
Sbjct: 261 KEDINAIEMEEDKRDLISREISKFRDTHKKLEEEK-----------GKKEKERQEIEKER 309

Query: 84  AALEQPCEGSLTRPKKAIPAGCGDEEEEEEE 114
              E+  E    R ++        E E+E+E
Sbjct: 310 RERERERERERERREREREREREREREKEKE 340


>gi|239745079 PREDICTED: Putative golgin subfamily A member 6-like
           protein 6 [Homo sapiens]
          Length = 724

 Score = 44.7 bits (104), Expect = 2e-05
 Identities = 23/79 (29%), Positives = 52/79 (65%), Gaps = 6/79 (7%)

Query: 13  TKDMGKMLGGEEEKDPDAQKKEEERQEALRQQEEERKAKHARMEAEREKVRQQIRDKYGL 72
           T++  + +G +EEK  + ++K +E++E +R+QEE+ + +  ++  + EK+R+Q   +  +
Sbjct: 608 TQEQEEKMGEQEEKMCEQEEKMQEQEEKMRRQEEKIREQEKKIREQEEKIREQ---EEMM 664

Query: 73  KKKEEKEAEEKAALEQPCE 91
           +++EEK  E++   E+ CE
Sbjct: 665 QEQEEKMWEQE---EKMCE 680



 Score = 42.0 bits (97), Expect = 1e-04
 Identities = 23/92 (25%), Positives = 53/92 (57%), Gaps = 7/92 (7%)

Query: 23  EEEKDPDAQKKEEERQEALRQQEEERKAKHARMEAEREKVRQQIRDKYGLKKKEEKEAEE 82
           +EE   + ++K  E++E + +QEE+ + +  +M  + EK+R+Q +    ++++EEK  E+
Sbjct: 604 QEEMTQEQEEKMGEQEEKMCEQEEKMQEQEEKMRRQEEKIREQEKK---IREQEEKIREQ 660

Query: 83  KAALEQPCEGSLTRPKKAIPAGCGDEEEEEEE 114
           +  +++  E    + +K     C  EE+ +E+
Sbjct: 661 EEMMQEQEEKMWEQEEKM----CEQEEKMQEQ 688



 Score = 38.9 bits (89), Expect = 0.001
 Identities = 27/101 (26%), Positives = 57/101 (56%), Gaps = 12/101 (11%)

Query: 23  EEEKDPDAQKKEEERQEALRQQEEERKAKHARMEAEREKVRQQ----IRDKYGLKKKEEK 78
           E+E+    ++K  E++E +R+QEE+   +  +M  + EK+R+Q     R +  ++++EEK
Sbjct: 534 EQEEIWRQKEKIHEQEEKIRKQEEKMWRQEEKMHDQEEKIREQEEKVWRQEEKIREQEEK 593

Query: 79  EAEEKAALEQPCEGSLTRPKKAIPAGCGDEEE---EEEESI 116
             E++  + +  E +  + +K      G++EE   E+EE +
Sbjct: 594 IREQEEKIREQEEMTQEQEEK-----MGEQEEKMCEQEEKM 629



 Score = 38.1 bits (87), Expect = 0.002
 Identities = 22/74 (29%), Positives = 45/74 (60%), Gaps = 8/74 (10%)

Query: 23  EEEKDPDAQKKEEE------RQEALRQQEEERKAKHARMEAEREKVRQQ--IRDKYGLKK 74
           EEEK  + +K++E+      ++E +R+QEE+ + +  +M  + EK+ +Q  IR++   ++
Sbjct: 462 EEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEEKMWRQEEKIHEQEKIREEEKRQE 521

Query: 75  KEEKEAEEKAALEQ 88
           +EE   +E+   EQ
Sbjct: 522 QEEMWRQEEKIREQ 535



 Score = 38.1 bits (87), Expect = 0.002
 Identities = 21/70 (30%), Positives = 41/70 (58%), Gaps = 4/70 (5%)

Query: 23  EEEKDPDAQKKEEERQEALRQQEEERKAKHARMEAEREKVRQQ----IRDKYGLKKKEEK 78
           +EEK  + +KK  E++E +R+QEE  + +  +M  + EK+ +Q       +  ++++EEK
Sbjct: 639 QEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEK 698

Query: 79  EAEEKAALEQ 88
             E++  L Q
Sbjct: 699 MWEQEVRLRQ 708



 Score = 38.1 bits (87), Expect = 0.002
 Identities = 21/78 (26%), Positives = 45/78 (57%), Gaps = 4/78 (5%)

Query: 14  KDMGKMLGGEEEKDPDAQKKEEERQEALRQQEEERKAKHARMEAEREKVRQQ----IRDK 69
           ++  K +  +EEK  + ++  +E++E + +QEE+   +  +M+ + EK+R+Q       +
Sbjct: 644 REQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQE 703

Query: 70  YGLKKKEEKEAEEKAALE 87
             L+++EEK  E +  LE
Sbjct: 704 VRLRQQEEKMQEHQEHLE 721



 Score = 37.7 bits (86), Expect = 0.003
 Identities = 26/96 (27%), Positives = 51/96 (53%), Gaps = 6/96 (6%)

Query: 24  EEKDPDAQKKEEERQEALRQQEEERKAKHARMEAEREKVRQQ---IRDKYGLKKKEEKEA 80
           EEK  + ++K  E++E +R+QEE+ + +   M  + EK+R+Q   + +K    +++E+  
Sbjct: 374 EEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMM 433

Query: 81  EEKAALEQPCEGSLTRPKKAIPAGCGDEEEEEEESI 116
            EK    +  E  +   +K       +E+ +EEE I
Sbjct: 434 WEKEEKIRELEEKMHEQEKIREQ---EEKRQEEEKI 466



 Score = 37.4 bits (85), Expect = 0.004
 Identities = 28/95 (29%), Positives = 52/95 (54%), Gaps = 7/95 (7%)

Query: 25  EKDPDAQKKEE---ERQEALRQQEEERKAKHARMEAEREKVRQQ--IRDKYGLKKKEEKE 79
           EK+   +++EE   E++E +R+QEE    K  ++    EK+ +Q  IR++   +++EEK 
Sbjct: 407 EKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKI 466

Query: 80  AEEKAALEQPCEGSLTRPKKAIPAGCGDEEEEEEE 114
            E++   EQ  E  + R ++ I        E+EE+
Sbjct: 467 REQEKRQEQ--EAKMWRQEEKIREQEEKIREQEEK 499



 Score = 34.7 bits (78), Expect = 0.024
 Identities = 24/70 (34%), Positives = 43/70 (61%), Gaps = 5/70 (7%)

Query: 18  KMLGGEEEKDPDAQKKEEERQEALRQQEEERKAKHARMEAER--EKVRQQIRDKYGLKKK 75
           +M+  +EEK  + ++K  E QE +R+QEE+R+ +    E E+  E+  +  R +  ++++
Sbjct: 431 EMMWEKEEKIRELEEKMHE-QEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQ 489

Query: 76  EEK--EAEEK 83
           EEK  E EEK
Sbjct: 490 EEKIREQEEK 499



 Score = 34.3 bits (77), Expect = 0.031
 Identities = 18/61 (29%), Positives = 39/61 (63%), Gaps = 1/61 (1%)

Query: 23  EEEKDPDAQKKEEERQEALRQQEEERKAKHARMEAEREKVRQQIRDKYGLKKKEEKEAEE 82
           +EEK    ++K  E+++ +R+QEE+ + +   M+ + EK+ +Q  +K   ++++ +E EE
Sbjct: 632 QEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQ-EEKMCEQEEKMQEQEE 690

Query: 83  K 83
           K
Sbjct: 691 K 691



 Score = 33.9 bits (76), Expect = 0.040
 Identities = 17/69 (24%), Positives = 41/69 (59%), Gaps = 3/69 (4%)

Query: 23  EEEKDPDAQKKEEERQEALRQQEEERKAKHARMEAEREKVR---QQIRDKYGLKKKEEKE 79
           +EE   + ++K   ++E + ++EE+ + +   M  + EK+R   +++ ++  ++++EEK 
Sbjct: 401 QEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKR 460

Query: 80  AEEKAALEQ 88
            EE+   EQ
Sbjct: 461 QEEEKIREQ 469



 Score = 33.9 bits (76), Expect = 0.040
 Identities = 19/69 (27%), Positives = 41/69 (59%), Gaps = 1/69 (1%)

Query: 15  DMGKMLGGEEEKDPDAQKKEEERQEALRQQEEERKAKHARMEAEREKVRQQIRDKYGLKK 74
           D  + +  +EEK    ++K  E++E +R+QEE+ + +    + + EK+ +Q  +K   ++
Sbjct: 568 DQEEKIREQEEKVWRQEEKIREQEEKIREQEEKIREQEEMTQEQEEKMGEQ-EEKMCEQE 626

Query: 75  KEEKEAEEK 83
           ++ +E EEK
Sbjct: 627 EKMQEQEEK 635



 Score = 32.7 bits (73), Expect = 0.089
 Identities = 25/75 (33%), Positives = 44/75 (58%), Gaps = 10/75 (13%)

Query: 23  EEEKDPDAQKKEEERQEALRQQE--EERKAKHARME----AEREKVRQQIRDKYGLKKK- 75
           E+EK  + ++K +E +E +R+QE  +E++AK  R E     + EK+R+Q    +  ++K 
Sbjct: 449 EQEKIREQEEKRQE-EEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEEKMWRQEEKI 507

Query: 76  --EEKEAEEKAALEQ 88
             +EK  EE+   EQ
Sbjct: 508 HEQEKIREEEKRQEQ 522



 Score = 32.7 bits (73), Expect = 0.089
 Identities = 22/97 (22%), Positives = 53/97 (54%), Gaps = 8/97 (8%)

Query: 23  EEEKDPDAQKKEEERQEALRQQEEERKAKHARMEAEREKVRQQIRDKYGLKKKEEKEAEE 82
           +EEK  + ++K   ++E + +QE+ R+ +  + + E  +  ++IR++  + +++EK  E+
Sbjct: 489 QEEKIREQEEKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKIHEQ 548

Query: 83  KAALEQPCEGSLTRPKKAIPAGCGDEEE---EEEESI 116
           +  + +  E    + +K       D+EE   E+EE +
Sbjct: 549 EEKIRKQEEKMWRQEEK-----MHDQEEKIREQEEKV 580



 Score = 32.7 bits (73), Expect = 0.089
 Identities = 28/106 (26%), Positives = 50/106 (47%), Gaps = 8/106 (7%)

Query: 14  KDMGKMLGGEEEKDPDAQKKEEERQEALRQQE-----EERKAKHARMEAEREKVRQQIRD 68
           K   KM   EE+     +K  E+ ++  RQ+E     EE+  +      E+E++ Q+  +
Sbjct: 554 KQEEKMWRQEEKMHDQEEKIREQEEKVWRQEEKIREQEEKIREQEEKIREQEEMTQEQEE 613

Query: 69  KYGLKKKEEKEAEEKAALEQPCEGSLTRPKKAIPAGCGDEEEEEEE 114
           K G ++++  E EEK    Q  E  + R ++ I        E+EE+
Sbjct: 614 KMGEQEEKMCEQEEKM---QEQEEKMRRQEEKIREQEKKIREQEEK 656



 Score = 32.3 bits (72), Expect = 0.12
 Identities = 17/66 (25%), Positives = 41/66 (62%), Gaps = 2/66 (3%)

Query: 23  EEEKDPDAQKKEEERQEALRQQEEERKAKHARMEAEREKVRQQIRDKYGLKKKEEKEAEE 82
           +EEK    ++K +E +E +++QEE+ + +  ++  + EK+R+Q  ++   +K+E+   +E
Sbjct: 359 QEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQ--EEMMWEKEEKMRRQE 416

Query: 83  KAALEQ 88
           +   E+
Sbjct: 417 EMMWEK 422



 Score = 31.2 bits (69), Expect = 0.26
 Identities = 16/61 (26%), Positives = 35/61 (57%)

Query: 23  EEEKDPDAQKKEEERQEALRQQEEERKAKHARMEAEREKVRQQIRDKYGLKKKEEKEAEE 82
           E+E+    Q+++  RQE +  ++EE+  +   M  E+E+  ++  +    K+++ +E EE
Sbjct: 386 EQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEE 445

Query: 83  K 83
           K
Sbjct: 446 K 446



 Score = 31.2 bits (69), Expect = 0.26
 Identities = 24/94 (25%), Positives = 50/94 (53%), Gaps = 4/94 (4%)

Query: 23  EEEKDPDAQKKEEERQEALRQQEEERKAKHARMEAE--REKVRQQIRDKYGLKKKEEKEA 80
           +EE   + ++K  E +E + +QE+ R+ +  R E E  RE+ ++Q ++    +++E+   
Sbjct: 429 QEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIRE 488

Query: 81  EEKAALEQPCEGSLTRPKKAIPAGCGDEEEEEEE 114
           +E+   EQ  E  + R ++ I       EEE+ +
Sbjct: 489 QEEKIREQ--EEKMWRQEEKIHEQEKIREEEKRQ 520



 Score = 30.4 bits (67), Expect = 0.44
 Identities = 23/78 (29%), Positives = 37/78 (47%), Gaps = 1/78 (1%)

Query: 6   KQALGGATKDMGKMLGGEEEKDPDAQKKEEERQEALRQQEEERKAKHARMEAEREKVRQQ 65
           +Q L      +GK L     K   AQ +E E    L QQ+EE+  +      E E+  Q+
Sbjct: 321 QQQLQAEADHLGKELQSVSAK-LQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQE 379

Query: 66  IRDKYGLKKKEEKEAEEK 83
             +K   ++++ +E EEK
Sbjct: 380 QEEKIREQEEKIREQEEK 397



 Score = 30.0 bits (66), Expect = 0.58
 Identities = 17/71 (23%), Positives = 38/71 (53%)

Query: 18  KMLGGEEEKDPDAQKKEEERQEALRQQEEERKAKHARMEAEREKVRQQIRDKYGLKKKEE 77
           KM   EE+     +K  E+ ++  RQ+E+  + +  R E +R++  +  R +  ++++EE
Sbjct: 478 KMWRQEEKIREQEEKIREQEEKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEE 537

Query: 78  KEAEEKAALEQ 88
              +++   EQ
Sbjct: 538 IWRQKEKIHEQ 548



 Score = 29.6 bits (65), Expect = 0.76
 Identities = 25/101 (24%), Positives = 50/101 (49%), Gaps = 11/101 (10%)

Query: 25  EKDPDAQKKEE---ERQEALRQQEE-----ERKAKHARMEAEREKVRQQIR---DKYGLK 73
           EK+   +++EE   E++E +R+ EE     E+  +      E EK+R+Q +    +  + 
Sbjct: 421 EKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMW 480

Query: 74  KKEEKEAEEKAALEQPCEGSLTRPKKAIPAGCGDEEEEEEE 114
           ++EEK  E++  + +  E    + +K        EEE+ +E
Sbjct: 481 RQEEKIREQEEKIREQEEKMWRQEEKIHEQEKIREEEKRQE 521


>gi|78190492 retinitis pigmentosa GTPase regulator isoform C [Homo
           sapiens]
          Length = 1152

 Score = 44.3 bits (103), Expect = 3e-05
 Identities = 29/105 (27%), Positives = 55/105 (52%), Gaps = 13/105 (12%)

Query: 21  GGEEE----KDPDAQKKEEERQEALRQQEEERKAKHARMEAEREKVRQQIRDKYGLKKKE 76
           GGEEE    ++ +  ++EEE +E   + +EE + +    E E+E+  ++  ++ G ++K 
Sbjct: 730 GGEEEHGEGEEEEGDREEEEEKEG--EGKEEGEGEEVEGEREKEEGERKKEERAGKEEKG 787

Query: 77  EKEAEEKAALEQPCEGSLTRPKKA-------IPAGCGDEEEEEEE 114
           E+E ++    E+  EG     ++        +  G G+ EEEEEE
Sbjct: 788 EEEGDQGEGEEEETEGRGEEKEEGGEVEGGEVEEGKGEREEEEEE 832



 Score = 39.7 bits (91), Expect = 7e-04
 Identities = 31/103 (30%), Positives = 49/103 (47%), Gaps = 9/103 (8%)

Query: 12  ATKDMGKMLGGEEEKDPDAQKKEEERQEALRQQEEERKAKHARMEAEREKVRQQIRDKYG 71
           A K+  K   GEE++    QK+ E+  +  R QE E   +    E E E+  ++  ++  
Sbjct: 697 AEKEEWKKRDGEEQE----QKEREQGHQKERNQEMEEGGEEEHGEGEEEEGDREEEEEKE 752

Query: 72  LKKKEEKEAEEKAALEQPCEGSLTRPKKAIPAGCGDEEEEEEE 114
            + KEE E EE     +  EG   + ++A     G EE+ EEE
Sbjct: 753 GEGKEEGEGEEVEGEREKEEGERKKEERA-----GKEEKGEEE 790



 Score = 38.9 bits (89), Expect = 0.001
 Identities = 29/94 (30%), Positives = 45/94 (47%), Gaps = 9/94 (9%)

Query: 22   GEEEKDPDAQKKEEERQEALRQQEEERKAKHARMEAEREKVRQQIRDKYGLKKKEEKEAE 81
            GEEE+     ++EE  +E   + E E + +    E E  +V  ++  + G  + EE+E E
Sbjct: 981  GEEEEGEGEGEEEEGEEEGEEEGEGEEEGEGEGEEEEEGEVEGEVEGEEGEGEGEEEEGE 1040

Query: 82   EKA-ALEQPCEGSLTRPKKAIPAGCGDEEEEEEE 114
            E+    E+  EG   R  +        EEEEEEE
Sbjct: 1041 EEGEEREKEGEGEENRRNR--------EEEEEEE 1066



 Score = 36.2 bits (82), Expect = 0.008
 Identities = 31/113 (27%), Positives = 50/113 (44%), Gaps = 12/113 (10%)

Query: 11  GATKDMGKMLGGEEEKDPDAQKKE---------EERQEALRQQEEERKAKHARMEAEREK 61
           G  +  G+ + GE EK+   +KKE         EE  +    +EEE + +    E   E 
Sbjct: 755 GKEEGEGEEVEGEREKEEGERKKEERAGKEEKGEEEGDQGEGEEEETEGRGEEKEEGGEV 814

Query: 62  VRQQIRDKYGLKKKEEKEAEEKAALEQPCEGSLTRPKKAIPAGCGDEEEEEEE 114
              ++ +  G +++EE+E E +   E+  EG     +     G G  EEE EE
Sbjct: 815 EGGEVEEGKGEREEEEEEGEGE---EEEGEGEEEEGEGEEEEGEGKGEEEGEE 864



 Score = 35.8 bits (81), Expect = 0.011
 Identities = 31/98 (31%), Positives = 48/98 (48%), Gaps = 4/98 (4%)

Query: 17  GKMLGGEEEKDPDAQKKEEERQEALRQQEEERKAKHARMEAEREKVRQQIRDKYGLKKKE 76
           GK   GEEE D   Q + EE +   R +E+E   +    E E  K  ++  ++ G  ++E
Sbjct: 782 GKEEKGEEEGD---QGEGEEEETEGRGEEKEEGGEVEGGEVEEGKGEREEEEEEGEGEEE 838

Query: 77  EKEAEEKAALEQPCEGSLTRPKKAIPAGCGDEEEEEEE 114
           E E EE+    +  EG   + ++    G G+EE EE E
Sbjct: 839 EGEGEEEEGEGEEEEGE-GKGEEEGEEGEGEEEGEEGE 875



 Score = 34.7 bits (78), Expect = 0.024
 Identities = 26/93 (27%), Positives = 43/93 (46%)

Query: 22  GEEEKDPDAQKKEEERQEALRQQEEERKAKHARMEAEREKVRQQIRDKYGLKKKEEKEAE 81
           GEEE + + +++E E +     +E E + +    E E E    +  ++ G  + EE+E E
Sbjct: 904 GEEEGEGEGEEEEGEGKGEEEGEEGEGEGEEEEGEGEGEDGEGEGEEEEGEWEGEEEEGE 963

Query: 82  EKAALEQPCEGSLTRPKKAIPAGCGDEEEEEEE 114
            +   E   EG     +     G G+ EEEE E
Sbjct: 964 GEGEEEGEGEGEEGEGEGEEEEGEGEGEEEEGE 996



 Score = 34.3 bits (77), Expect = 0.031
 Identities = 24/110 (21%), Positives = 56/110 (50%), Gaps = 7/110 (6%)

Query: 11   GATKDMGKMLGGEEEKDPDAQKKEEERQEALRQQEEERKAKHARMEAEREKVRQQIRDKY 70
            G  ++ G++ G  E ++ + + +EEE +E   ++E+E + +  R   E E+  +    + 
Sbjct: 1013 GEEEEEGEVEGEVEGEEGEGEGEEEEGEEEGEEREKEGEGEENRRNREEEEEEEGKYQET 1072

Query: 71   GLKKKEEKEAEEKAALEQPCEGSL------TRPKKAIPAGCGDEEEEEEE 114
            G ++ E ++ EE   + +  +GS+      T  KK++    G+ +E+  +
Sbjct: 1073 GEEENERQDGEEYKKVSK-IKGSVKYGKHKTYQKKSVTNTQGNGKEQRSK 1121



 Score = 33.9 bits (76), Expect = 0.040
 Identities = 30/105 (28%), Positives = 52/105 (49%), Gaps = 6/105 (5%)

Query: 10  GGATKDMGKMLGGEEEKDPDAQKKEEERQEALRQQEEERKAKHARMEAEREKVRQQIRDK 69
           G   ++ G++ GGE E+    +++EEE  E    +EEE + +    E E E+   +  ++
Sbjct: 805 GEEKEEGGEVEGGEVEEGKGEREEEEEEGEG---EEEEGEGEEEEGEGEEEEGEGK-GEE 860

Query: 70  YGLKKKEEKEAEEKAALEQPCEGSLTRPKKAIPAGCGDEEEEEEE 114
            G + + E+E EE     +  EG     ++    G G+EEE E E
Sbjct: 861 EGEEGEGEEEGEEGEGEGEEEEGEGEGEEEG--EGEGEEEEGEGE 903



 Score = 33.1 bits (74), Expect = 0.069
 Identities = 28/100 (28%), Positives = 46/100 (46%), Gaps = 10/100 (10%)

Query: 22   GEEEKDPDAQKKEEERQEALRQQEEERKAKHARMEAEREKVRQQIRDKYGLKKKEEK--- 78
            GE E++    + EEE  E   ++E E + +    E E E+   +  ++ G ++ EE+   
Sbjct: 946  GEGEEEEGEWEGEEEEGEGEGEEEGEGEGEEGEGEGEEEEGEGEGEEEEGEEEGEEEGEG 1005

Query: 79   ----EAEEKAALEQPCEGSLTRPKKAIPAGCGDEEEEEEE 114
                E E +   E   EG +   +     G G+EEE EEE
Sbjct: 1006 EEEGEGEGEEEEEGEVEGEVEGEE---GEGEGEEEEGEEE 1042



 Score = 32.7 bits (73), Expect = 0.089
 Identities = 30/105 (28%), Positives = 49/105 (46%), Gaps = 3/105 (2%)

Query: 11  GATKDMGKMLGGEEEKDPDAQKKEEERQEALRQQEEERKAKHARMEAEREKVRQQIRDKY 70
           G   + GK    EEE++ + +++E E +E   + EEE      + E E E+   +   + 
Sbjct: 816 GGEVEEGKGEREEEEEEGEGEEEEGEGEEEEGEGEEEE--GEGKGEEEGEEGEGEEEGEE 873

Query: 71  GLKKKEEKEAEEKAALEQPCEGSLTRPK-KAIPAGCGDEEEEEEE 114
           G  + EE+E E +   E   EG     + +    G G+ EEEE E
Sbjct: 874 GEGEGEEEEGEGEGEEEGEGEGEEEEGEGEGEEEGEGEGEEEEGE 918



 Score = 31.6 bits (70), Expect = 0.20
 Identities = 29/104 (27%), Positives = 46/104 (44%), Gaps = 5/104 (4%)

Query: 11  GATKDMGKMLGGEEEKDPDAQKKEEERQEALRQQEEERKAKHARMEAEREKVRQQIRDKY 70
           G  ++ G+   GEEE +    + EEE  E   ++E E + +    E E E+  +   ++ 
Sbjct: 856 GKGEEEGEEGEGEEEGEEGEGEGEEEEGEGEGEEEGEGEGEEEEGEGEGEEEGEGEGEEE 915

Query: 71  GLKKKEEKEAEEKAALEQPCEGSLTRPKKAIPAGCGDEEEEEEE 114
             + K E+E EE        EG     +     G G+ EEEE E
Sbjct: 916 EGEGKGEEEGEEGEG-----EGEEEEGEGEGEDGEGEGEEEEGE 954



 Score = 31.2 bits (69), Expect = 0.26
 Identities = 30/101 (29%), Positives = 51/101 (50%), Gaps = 16/101 (15%)

Query: 14  KDMGKMLGGEEEKDPDAQKKEEERQEALRQQEEERKAKHARMEAEREKVRQQIRDKYGLK 73
           KD G+   GE E+  + +K+  E++E  ++  EE++ K      ERE+  Q+ R+     
Sbjct: 679 KDKGR---GEMERPGEGEKELAEKEEWKKRDGEEQEQK------EREQGHQKERN----- 724

Query: 74  KKEEKEAEEKAALEQPCEGSLTRPKKAIPAGCGDEEEEEEE 114
           ++ E+  EE+    +  EG   R ++    G G EE E EE
Sbjct: 725 QEMEEGGEEEHGEGEEEEGD--REEEEEKEGEGKEEGEGEE 763



 Score = 31.2 bits (69), Expect = 0.26
 Identities = 27/93 (29%), Positives = 44/93 (47%), Gaps = 1/93 (1%)

Query: 22  GEEEKDPDAQKKEEERQEALRQQEEERKAKHARMEAEREKVRQQIRDKYGLKKKEEKEAE 81
           GE E++    K EEE +E    +EE  + +    E E E   ++  +  G +++ E E E
Sbjct: 847 GEGEEEEGEGKGEEEGEEG-EGEEEGEEGEGEGEEEEGEGEGEEEGEGEGEEEEGEGEGE 905

Query: 82  EKAALEQPCEGSLTRPKKAIPAGCGDEEEEEEE 114
           E+   E   E    + ++    G G+ EEEE E
Sbjct: 906 EEGEGEGEEEEGEGKGEEEGEEGEGEGEEEEGE 938



 Score = 30.8 bits (68), Expect = 0.34
 Identities = 25/96 (26%), Positives = 43/96 (44%), Gaps = 11/96 (11%)

Query: 21  GGEEEKDPDAQKKEEE--RQEALRQQEEERKAKHARMEAEREKVRQQIRDKYGLKKKEEK 78
           G E  +D + +K E++  R E  R  E E++        +R+   Q+ +++    +KE  
Sbjct: 665 GAEHWQDEEREKGEKDKGRGEMERPGEGEKELAEKEEWKKRDGEEQEQKEREQGHQKERN 724

Query: 79  EAEEKAALEQPCEGSLTRPKKAIPAGCGDEEEEEEE 114
           +  E+   E+  EG             GD EEEEE+
Sbjct: 725 QEMEEGGEEEHGEGEEEE---------GDREEEEEK 751



 Score = 30.8 bits (68), Expect = 0.34
 Identities = 30/104 (28%), Positives = 47/104 (45%), Gaps = 14/104 (13%)

Query: 17   GKMLGGEEEKDPDAQ----KKEEERQEALRQQEEERKAKHARMEAEREKVRQQIRDKYGL 72
            G+  G EEE + + +    + EEE  E   ++EE         E E E+   +  ++ G 
Sbjct: 928  GEGEGEEEEGEGEGEDGEGEGEEEEGEWEGEEEEGEGEGEEEGEGEGEEGEGEGEEEEGE 987

Query: 73   KKKEEKEAEEKAALEQPCEGSLTRPKKAIPAGCGDEEEEEEESI 116
             + EE+E EE+   E+  EG           G G+ EEEEE  +
Sbjct: 988  GEGEEEEGEEEG--EEEGEGE--------EEGEGEGEEEEEGEV 1021



 Score = 28.1 bits (61), Expect = 2.2
 Identities = 24/102 (23%), Positives = 44/102 (43%), Gaps = 10/102 (9%)

Query: 10   GGATKDMGKMLGGEEEKDPDAQ--KKEEERQEALRQQEEERKAKHARMEAEREKVRQQIR 67
            G    + G+  G EEE + + +  +KE E +E  R +EEE + +    E   E+  +Q  
Sbjct: 1023 GEVEGEEGEGEGEEEEGEEEGEEREKEGEGEENRRNREEEEEEEGKYQETGEEENERQDG 1082

Query: 68   DKY--------GLKKKEEKEAEEKAALEQPCEGSLTRPKKAI 101
            ++Y         +K  + K  ++K+       G   R K  +
Sbjct: 1083 EEYKKVSKIKGSVKYGKHKTYQKKSVTNTQGNGKEQRSKMPV 1124



 Score = 26.2 bits (56), Expect = 8.4
 Identities = 24/104 (23%), Positives = 45/104 (43%), Gaps = 11/104 (10%)

Query: 22   GEEEKDPDAQKKEEERQEALRQQEEERKAKHARMEAEREKVRQQIRDKYGL--KKKEEKE 79
            GE E++ + + +EEE  E   + E E        E   E+  ++ ++  G   ++  E+E
Sbjct: 1003 GEGEEEGEGEGEEEEEGEVEGEVEGEEGEGEGEEEEGEEEGEEREKEGEGEENRRNREEE 1062

Query: 80   AEEKAALEQPCEGSLTRPKKAIPAGCGDEEEEEEESILDTVLKY 123
             EE+   ++  E    R          D EE ++ S +   +KY
Sbjct: 1063 EEEEGKYQETGEEENERQ---------DGEEYKKVSKIKGSVKY 1097


>gi|157738649 neurofilament, medium polypeptide 150kDa isoform 1
           [Homo sapiens]
          Length = 916

 Score = 43.9 bits (102), Expect = 4e-05
 Identities = 31/111 (27%), Positives = 61/111 (54%), Gaps = 6/111 (5%)

Query: 5   MKQALGGATKDMGKMLGGEEEKDPDAQKKEEERQEALRQQEEERKAKHARMEAEREKVRQ 64
           M++AL   T+++   +  +EEK   A++KEEE +     +EEE  AK + ++A   +V++
Sbjct: 469 MEEALTAITEELAVSM--KEEKKEAAEEKEEEPEA----EEEEVAAKKSPVKATAPEVKE 522

Query: 65  QIRDKYGLKKKEEKEAEEKAALEQPCEGSLTRPKKAIPAGCGDEEEEEEES 115
           +  +K   + +EE+E E++ A     E   +  + +     G++EE E E+
Sbjct: 523 EEGEKEEEEGQEEEEEEDEGAKSDQAEEGGSEKEGSSEKEEGEQEEGETEA 573



 Score = 37.0 bits (84), Expect = 0.005
 Identities = 25/94 (26%), Positives = 48/94 (51%), Gaps = 3/94 (3%)

Query: 22  GEEEKDPDAQKKEEERQEALRQQEEERKAKHARMEAEREKVRQQIRDKYGLKKKEEKEAE 81
           GE+E++ + Q++EEE  E  +  + E         +E+E+  Q+  +     + EE EA+
Sbjct: 525 GEKEEE-EGQEEEEEEDEGAKSDQAEEGGSEKEGSSEKEEGEQEEGETEAEAEGEEAEAK 583

Query: 82  EKAALEQPCEGSLTRPKKAIPAGCGDEEEEEEES 115
           E+  +E+  E   T  K+ + A    E+ E+ +S
Sbjct: 584 EEKKVEEKSEEVAT--KEELVADAKVEKPEKAKS 615



 Score = 35.4 bits (80), Expect = 0.014
 Identities = 24/85 (28%), Positives = 41/85 (48%), Gaps = 8/85 (9%)

Query: 21  GGEEEKDPDAQKKEEERQEALRQQE-----EERKAKHARMEAEREKVRQQIRDKYGLKKK 75
           G EEE++ D   K ++ +E   ++E     EE + +    EAE E    + +++   KK 
Sbjct: 532 GQEEEEEEDEGAKSDQAEEGGSEKEGSSEKEEGEQEEGETEAEAEGEEAEAKEE---KKV 588

Query: 76  EEKEAEEKAALEQPCEGSLTRPKKA 100
           EEK  E     E   +  + +P+KA
Sbjct: 589 EEKSEEVATKEELVADAKVEKPEKA 613



 Score = 34.7 bits (78), Expect = 0.024
 Identities = 25/99 (25%), Positives = 45/99 (45%), Gaps = 2/99 (2%)

Query: 11  GATKDMGKMLGGEEEKDPDAQKKEEERQEALRQQEEERKAKHARMEAEREKVRQQIRDKY 70
           GA  D  +   G  EK+  ++K+E E++E   + E E +   A+ E + E+  +++  K 
Sbjct: 542 GAKSDQAEE--GGSEKEGSSEKEEGEQEEGETEAEAEGEEAEAKEEKKVEEKSEEVATKE 599

Query: 71  GLKKKEEKEAEEKAALEQPCEGSLTRPKKAIPAGCGDEE 109
            L    + E  EKA    P      + K  +P    +E+
Sbjct: 600 ELVADAKVEKPEKAKSPVPKSPVEEKGKSPVPKSPVEEK 638



 Score = 32.0 bits (71), Expect = 0.15
 Identities = 25/98 (25%), Positives = 45/98 (45%), Gaps = 12/98 (12%)

Query: 22  GEEEKDPDAQKKEEERQEALRQQEEERK----AKHARMEAEREKVRQQIRDKYGLKKKEE 77
           GE++++ + + KE  ++E + ++EE+ K     K A    + E V + +     +K   E
Sbjct: 699 GEQKEEEEKEVKEAPKEEKVEKKEEKPKDVPEKKKAESPVKEEAVAEVVTITKSVKVHLE 758

Query: 78  KEAEEKAALEQPCEGSLTRPKKAIPAGCGDEEEEEEES 115
           KE +E        EG   + +K      G+   EEE S
Sbjct: 759 KETKE--------EGKPLQQEKEKEKAGGEGGSEEEGS 788



 Score = 30.8 bits (68), Expect = 0.34
 Identities = 24/99 (24%), Positives = 49/99 (49%), Gaps = 2/99 (2%)

Query: 23  EEEKDPDAQKKEEERQEA-LRQQEEERKAKHARMEAEREKVRQQIRDKYGLKKKEEKEAE 81
           E+ K P  +   EE+ ++ + +   E KAK    ++  E+ + +     G +K+EE++  
Sbjct: 650 EKGKSPVPKSPVEEKGKSPVSKSPVEEKAKSPVPKSPVEEAKSKAEVGKGEQKEEEEKEV 709

Query: 82  EKAALEQPCEGSLTRPKKAIPAGCGDEEEEEEESILDTV 120
           ++A  E+  E    +PK  +P     E   +EE++ + V
Sbjct: 710 KEAPKEEKVEKKEEKPKD-VPEKKKAESPVKEEAVAEVV 747



 Score = 30.4 bits (67), Expect = 0.44
 Identities = 28/102 (27%), Positives = 50/102 (49%), Gaps = 5/102 (4%)

Query: 23  EEEKDPDAQKKEEERQEALRQQEEERKAKHARMEAEREKVRQQIRDKYGLKKKEEKEAEE 82
           +EE  P  Q+KE+E+       EEE   K A+  + +E +   +  +   K++ E+E +E
Sbjct: 762 KEEGKPLQQEKEKEKAGGEGGSEEEGSDKGAK-GSRKEDI--AVNGEVEGKEEVEQETKE 818

Query: 83  KAALEQPCEGSLTRPKKAIPAG--CGDEEEEEEESILDTVLK 122
           K +  +  +G +T      PA    G ++ EE+  +  TV K
Sbjct: 819 KGSGREEEKGVVTNGLDLSPADEKKGGDKSEEKVVVTKTVEK 860



 Score = 29.6 bits (65), Expect = 0.76
 Identities = 25/97 (25%), Positives = 41/97 (42%), Gaps = 18/97 (18%)

Query: 23  EEEKDPDAQKKEEERQEALRQQ-----EEERKAKHARMEAEREKVRQQIRDKYGLKKKEE 77
           EE K  D + + EE   A+ ++     +EE+K      E E E   +++  K    K   
Sbjct: 458 EETKVEDEKSEMEEALTAITEELAVSMKEEKKEAAEEKEEEPEAEEEEVAAKKSPVKATA 517

Query: 78  KEAEEKAALEQPCEGSLTRPKKAIPAGCGDEEEEEEE 114
            E +E+   ++  EG              +EEEEE+E
Sbjct: 518 PEVKEEEGEKEEEEGQ-------------EEEEEEDE 541



 Score = 28.1 bits (61), Expect = 2.2
 Identities = 20/88 (22%), Positives = 37/88 (42%)

Query: 22  GEEEKDPDAQKKEEERQEALRQQEEERKAKHARMEAEREKVRQQIRDKYGLKKKEEKEAE 81
           GEE +  + +K EE+ +E   ++E    AK  + E  +  V +   ++ G     +   E
Sbjct: 577 GEEAEAKEEKKVEEKSEEVATKEELVADAKVEKPEKAKSPVPKSPVEEKGKSPVPKSPVE 636

Query: 82  EKAALEQPCEGSLTRPKKAIPAGCGDEE 109
           EK     P      + K  +P    +E+
Sbjct: 637 EKGKSPVPKSPVEEKGKSPVPKSPVEEK 664



 Score = 27.7 bits (60), Expect = 2.9
 Identities = 21/93 (22%), Positives = 39/93 (41%)

Query: 23  EEEKDPDAQKKEEERQEALRQQEEERKAKHARMEAEREKVRQQIRDKYGLKKKEEKEAEE 82
           E E++  A KK   +  A   +EEE + +    + E E+  +  +     +   EKE   
Sbjct: 500 EAEEEEVAAKKSPVKATAPEVKEEEGEKEEEEGQEEEEEEDEGAKSDQAEEGGSEKEGSS 559

Query: 83  KAALEQPCEGSLTRPKKAIPAGCGDEEEEEEES 115
           +    +  EG      +   A   +E++ EE+S
Sbjct: 560 EKEEGEQEEGETEAEAEGEEAEAKEEKKVEEKS 592


>gi|157738641 neurofilament, medium polypeptide 150kDa isoform 2
           [Homo sapiens]
          Length = 540

 Score = 43.9 bits (102), Expect = 4e-05
 Identities = 31/111 (27%), Positives = 61/111 (54%), Gaps = 6/111 (5%)

Query: 5   MKQALGGATKDMGKMLGGEEEKDPDAQKKEEERQEALRQQEEERKAKHARMEAEREKVRQ 64
           M++AL   T+++   +  +EEK   A++KEEE +     +EEE  AK + ++A   +V++
Sbjct: 93  MEEALTAITEELAVSM--KEEKKEAAEEKEEEPEA----EEEEVAAKKSPVKATAPEVKE 146

Query: 65  QIRDKYGLKKKEEKEAEEKAALEQPCEGSLTRPKKAIPAGCGDEEEEEEES 115
           +  +K   + +EE+E E++ A     E   +  + +     G++EE E E+
Sbjct: 147 EEGEKEEEEGQEEEEEEDEGAKSDQAEEGGSEKEGSSEKEEGEQEEGETEA 197



 Score = 37.0 bits (84), Expect = 0.005
 Identities = 25/94 (26%), Positives = 48/94 (51%), Gaps = 3/94 (3%)

Query: 22  GEEEKDPDAQKKEEERQEALRQQEEERKAKHARMEAEREKVRQQIRDKYGLKKKEEKEAE 81
           GE+E++ + Q++EEE  E  +  + E         +E+E+  Q+  +     + EE EA+
Sbjct: 149 GEKEEE-EGQEEEEEEDEGAKSDQAEEGGSEKEGSSEKEEGEQEEGETEAEAEGEEAEAK 207

Query: 82  EKAALEQPCEGSLTRPKKAIPAGCGDEEEEEEES 115
           E+  +E+  E   T  K+ + A    E+ E+ +S
Sbjct: 208 EEKKVEEKSEEVAT--KEELVADAKVEKPEKAKS 239



 Score = 35.4 bits (80), Expect = 0.014
 Identities = 24/85 (28%), Positives = 41/85 (48%), Gaps = 8/85 (9%)

Query: 21  GGEEEKDPDAQKKEEERQEALRQQE-----EERKAKHARMEAEREKVRQQIRDKYGLKKK 75
           G EEE++ D   K ++ +E   ++E     EE + +    EAE E    + +++   KK 
Sbjct: 156 GQEEEEEEDEGAKSDQAEEGGSEKEGSSEKEEGEQEEGETEAEAEGEEAEAKEE---KKV 212

Query: 76  EEKEAEEKAALEQPCEGSLTRPKKA 100
           EEK  E     E   +  + +P+KA
Sbjct: 213 EEKSEEVATKEELVADAKVEKPEKA 237



 Score = 34.7 bits (78), Expect = 0.024
 Identities = 25/99 (25%), Positives = 45/99 (45%), Gaps = 2/99 (2%)

Query: 11  GATKDMGKMLGGEEEKDPDAQKKEEERQEALRQQEEERKAKHARMEAEREKVRQQIRDKY 70
           GA  D  +   G  EK+  ++K+E E++E   + E E +   A+ E + E+  +++  K 
Sbjct: 166 GAKSDQAEE--GGSEKEGSSEKEEGEQEEGETEAEAEGEEAEAKEEKKVEEKSEEVATKE 223

Query: 71  GLKKKEEKEAEEKAALEQPCEGSLTRPKKAIPAGCGDEE 109
            L    + E  EKA    P      + K  +P    +E+
Sbjct: 224 ELVADAKVEKPEKAKSPVPKSPVEEKGKSPVPKSPVEEK 262



 Score = 32.0 bits (71), Expect = 0.15
 Identities = 25/98 (25%), Positives = 45/98 (45%), Gaps = 12/98 (12%)

Query: 22  GEEEKDPDAQKKEEERQEALRQQEEERK----AKHARMEAEREKVRQQIRDKYGLKKKEE 77
           GE++++ + + KE  ++E + ++EE+ K     K A    + E V + +     +K   E
Sbjct: 323 GEQKEEEEKEVKEAPKEEKVEKKEEKPKDVPEKKKAESPVKEEAVAEVVTITKSVKVHLE 382

Query: 78  KEAEEKAALEQPCEGSLTRPKKAIPAGCGDEEEEEEES 115
           KE +E        EG   + +K      G+   EEE S
Sbjct: 383 KETKE--------EGKPLQQEKEKEKAGGEGGSEEEGS 412



 Score = 30.8 bits (68), Expect = 0.34
 Identities = 24/99 (24%), Positives = 49/99 (49%), Gaps = 2/99 (2%)

Query: 23  EEEKDPDAQKKEEERQEA-LRQQEEERKAKHARMEAEREKVRQQIRDKYGLKKKEEKEAE 81
           E+ K P  +   EE+ ++ + +   E KAK    ++  E+ + +     G +K+EE++  
Sbjct: 274 EKGKSPVPKSPVEEKGKSPVSKSPVEEKAKSPVPKSPVEEAKSKAEVGKGEQKEEEEKEV 333

Query: 82  EKAALEQPCEGSLTRPKKAIPAGCGDEEEEEEESILDTV 120
           ++A  E+  E    +PK  +P     E   +EE++ + V
Sbjct: 334 KEAPKEEKVEKKEEKPKD-VPEKKKAESPVKEEAVAEVV 371



 Score = 30.4 bits (67), Expect = 0.44
 Identities = 28/102 (27%), Positives = 50/102 (49%), Gaps = 5/102 (4%)

Query: 23  EEEKDPDAQKKEEERQEALRQQEEERKAKHARMEAEREKVRQQIRDKYGLKKKEEKEAEE 82
           +EE  P  Q+KE+E+       EEE   K A+  + +E +   +  +   K++ E+E +E
Sbjct: 386 KEEGKPLQQEKEKEKAGGEGGSEEEGSDKGAK-GSRKEDI--AVNGEVEGKEEVEQETKE 442

Query: 83  KAALEQPCEGSLTRPKKAIPAG--CGDEEEEEEESILDTVLK 122
           K +  +  +G +T      PA    G ++ EE+  +  TV K
Sbjct: 443 KGSGREEEKGVVTNGLDLSPADEKKGGDKSEEKVVVTKTVEK 484



 Score = 29.6 bits (65), Expect = 0.76
 Identities = 25/97 (25%), Positives = 41/97 (42%), Gaps = 18/97 (18%)

Query: 23  EEEKDPDAQKKEEERQEALRQQ-----EEERKAKHARMEAEREKVRQQIRDKYGLKKKEE 77
           EE K  D + + EE   A+ ++     +EE+K      E E E   +++  K    K   
Sbjct: 82  EETKVEDEKSEMEEALTAITEELAVSMKEEKKEAAEEKEEEPEAEEEEVAAKKSPVKATA 141

Query: 78  KEAEEKAALEQPCEGSLTRPKKAIPAGCGDEEEEEEE 114
            E +E+   ++  EG              +EEEEE+E
Sbjct: 142 PEVKEEEGEKEEEEGQ-------------EEEEEEDE 165



 Score = 28.1 bits (61), Expect = 2.2
 Identities = 20/88 (22%), Positives = 37/88 (42%)

Query: 22  GEEEKDPDAQKKEEERQEALRQQEEERKAKHARMEAEREKVRQQIRDKYGLKKKEEKEAE 81
           GEE +  + +K EE+ +E   ++E    AK  + E  +  V +   ++ G     +   E
Sbjct: 201 GEEAEAKEEKKVEEKSEEVATKEELVADAKVEKPEKAKSPVPKSPVEEKGKSPVPKSPVE 260

Query: 82  EKAALEQPCEGSLTRPKKAIPAGCGDEE 109
           EK     P      + K  +P    +E+
Sbjct: 261 EKGKSPVPKSPVEEKGKSPVPKSPVEEK 288



 Score = 27.7 bits (60), Expect = 2.9
 Identities = 21/93 (22%), Positives = 39/93 (41%)

Query: 23  EEEKDPDAQKKEEERQEALRQQEEERKAKHARMEAEREKVRQQIRDKYGLKKKEEKEAEE 82
           E E++  A KK   +  A   +EEE + +    + E E+  +  +     +   EKE   
Sbjct: 124 EAEEEEVAAKKSPVKATAPEVKEEEGEKEEEEGQEEEEEEDEGAKSDQAEEGGSEKEGSS 183

Query: 83  KAALEQPCEGSLTRPKKAIPAGCGDEEEEEEES 115
           +    +  EG      +   A   +E++ EE+S
Sbjct: 184 EKEEGEQEEGETEAEAEGEEAEAKEEKKVEEKS 216


>gi|239508778 PREDICTED: hypothetical protein, partial [Homo
           sapiens]
          Length = 123

 Score = 43.5 bits (101), Expect = 5e-05
 Identities = 27/95 (28%), Positives = 53/95 (55%), Gaps = 4/95 (4%)

Query: 24  EEKDPDAQKKEEERQEALRQQEEERKAKHARMEAEREKVRQQIRDKYGLKK----KEEKE 79
           EE++    K++E+R+E  +++E+++K K      E+E+  ++ + K   KK    +EE+E
Sbjct: 20  EEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEKKRKRKRKKKKEEEEREEEE 79

Query: 80  AEEKAALEQPCEGSLTRPKKAIPAGCGDEEEEEEE 114
            EE+   E+  +    R KK       +EEEE+++
Sbjct: 80  EEEEEEKEEEEKEEGRRRKKKKKRRRKEEEEEKKK 114



 Score = 43.1 bits (100), Expect = 7e-05
 Identities = 25/92 (27%), Positives = 48/92 (52%), Gaps = 18/92 (19%)

Query: 23  EEEKDPDAQKKEEERQEALRQQEEERKAKHARMEAEREKVRQQIRDKYGLKKKEEKEAEE 82
           E E+  + ++KE +R+E  +++ +E++ K    E E+ K +++   K   K+K++KE EE
Sbjct: 15  ETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEKKRKRKRKKKKEEEE 74

Query: 83  KAALEQPCEGSLTRPKKAIPAGCGDEEEEEEE 114
           +   E+                  +EEEE+EE
Sbjct: 75  REEEEE------------------EEEEEKEE 88



 Score = 43.1 bits (100), Expect = 7e-05
 Identities = 28/97 (28%), Positives = 57/97 (58%), Gaps = 8/97 (8%)

Query: 23  EEEKDPDAQKKEEERQEALRQQEEERKAKHA-----RMEAEREKVRQQIRDKYGLKKKEE 77
           EEEK+    K++E+R+E  +++E+++K K       + E E+++ R++ + K   +++EE
Sbjct: 22  EEEKEG---KRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEKKRKRKRKKKKEEEEREEE 78

Query: 78  KEAEEKAALEQPCEGSLTRPKKAIPAGCGDEEEEEEE 114
           +E EE+   E+  E    R KK       +EEE++++
Sbjct: 79  EEEEEEEKEEEEKEEGRRRKKKKKRRRKEEEEEKKKK 115



 Score = 42.7 bits (99), Expect = 9e-05
 Identities = 31/91 (34%), Positives = 45/91 (49%), Gaps = 9/91 (9%)

Query: 26  KDPDAQKKEEERQEALRQQEEERKAKHARMEAEREKVRQQIRDKYG--LKKKEEKEAEEK 83
           K    +KKE E  E   + EEE + +  R E  +EK +++ + K     +K++EKE EEK
Sbjct: 1   KKKKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEK 60

Query: 84  AALEQPCEGSLTRPKKAIPAGCGDEEEEEEE 114
               +       R KK       +EEEEEEE
Sbjct: 61  KRKRK-------RKKKKEEEEREEEEEEEEE 84



 Score = 41.2 bits (95), Expect = 3e-04
 Identities = 22/71 (30%), Positives = 46/71 (64%), Gaps = 1/71 (1%)

Query: 13  TKDMGKMLGGEEEKDPDAQKKEEERQEALRQQEEERKAKHARMEAEREKVRQQIRDKYGL 72
           TK+  K    EEE+    +K++++++E  R++EEE + +  + E E+E+ R++ + K   
Sbjct: 46  TKETEKRKEKEEEEKKRKRKRKKKKEEEEREEEEEEE-EEEKEEEEKEEGRRRKKKKKRR 104

Query: 73  KKKEEKEAEEK 83
           +K+EE+E ++K
Sbjct: 105 RKEEEEEKKKK 115



 Score = 35.8 bits (81), Expect = 0.011
 Identities = 16/52 (30%), Positives = 32/52 (61%)

Query: 23  EEEKDPDAQKKEEERQEALRQQEEERKAKHARMEAEREKVRQQIRDKYGLKK 74
           EEE++ + +++EEE++E  +++   RK K  R   E E+ +++ R +   KK
Sbjct: 72  EEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEEEEKKKKRRRKTKKK 123



 Score = 33.1 bits (74), Expect = 0.069
 Identities = 15/61 (24%), Positives = 38/61 (62%), Gaps = 2/61 (3%)

Query: 23  EEEKDPDAQKKEEERQEALRQQEEERKAKHARMEAEREKVRQQIRDKYGLKKKEEKEAEE 82
           + +K  + +++EEE +E   ++EEE K +  R + ++++ R++  ++   KKK  ++ ++
Sbjct: 65  KRKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEEEE--KKKKRRRKTKK 122

Query: 83  K 83
           K
Sbjct: 123 K 123


>gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo
           sapiens]
          Length = 750

 Score = 43.1 bits (100), Expect = 7e-05
 Identities = 24/95 (25%), Positives = 56/95 (58%), Gaps = 6/95 (6%)

Query: 23  EEEKDPDAQKKEEERQEALRQQEEERKAKHARMEAEREKVRQQ---IRDKYGLKKKEEKE 79
           +EEK  + ++K   ++E +R+QEE+R+ +  +M  + EK+R+Q   I+++    +++E++
Sbjct: 575 QEEKIREQEEKVWRQEEKIREQEEKRQEQEEKMWKQEEKIREQEEKIQEQEEKIREQEEK 634

Query: 80  AEEKAALEQPCEGSLTRPKKAIPAGCGDEEEEEEE 114
             E+  + Q  E  +   ++ +   C  EE+ +E+
Sbjct: 635 IREQEEMTQEQEEKMGEQEEKM---CEQEEKMQEQ 666



 Score = 42.0 bits (97), Expect = 1e-04
 Identities = 22/79 (27%), Positives = 51/79 (64%), Gaps = 6/79 (7%)

Query: 13  TKDMGKMLGGEEEKDPDAQKKEEERQEALRQQEEERKAKHARMEAEREKVRQQIRDKYGL 72
           T++  + +G +EEK  + ++K +E++E + +QEE+ + +  ++  + EK+R+Q   +  +
Sbjct: 642 TQEQEEKMGEQEEKMCEQEEKMQEQEETMWRQEEKIREQEKKIREQEEKIREQ---EEMM 698

Query: 73  KKKEEKEAEEKAALEQPCE 91
           +++EEK  E++   E+ CE
Sbjct: 699 QEQEEKMWEQE---EKMCE 714



 Score = 39.7 bits (91), Expect = 7e-04
 Identities = 23/92 (25%), Positives = 52/92 (56%), Gaps = 7/92 (7%)

Query: 23  EEEKDPDAQKKEEERQEALRQQEEERKAKHARMEAEREKVRQQIRDKYGLKKKEEKEAEE 82
           +EE   + ++K  E++E + +QEE+ + +   M  + EK+R+Q +    ++++EEK  E+
Sbjct: 638 QEEMTQEQEEKMGEQEEKMCEQEEKMQEQEETMWRQEEKIREQEKK---IREQEEKIREQ 694

Query: 83  KAALEQPCEGSLTRPKKAIPAGCGDEEEEEEE 114
           +  +++  E    + +K     C  EE+ +E+
Sbjct: 695 EEMMQEQEEKMWEQEEKM----CEQEEKMQEQ 722



 Score = 38.1 bits (87), Expect = 0.002
 Identities = 21/70 (30%), Positives = 41/70 (58%), Gaps = 4/70 (5%)

Query: 23  EEEKDPDAQKKEEERQEALRQQEEERKAKHARMEAEREKVRQQ----IRDKYGLKKKEEK 78
           +EEK  + +KK  E++E +R+QEE  + +  +M  + EK+ +Q       +  ++++EEK
Sbjct: 673 QEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEK 732

Query: 79  EAEEKAALEQ 88
             E++  L Q
Sbjct: 733 MWEQEVRLRQ 742



 Score = 37.7 bits (86), Expect = 0.003
 Identities = 22/74 (29%), Positives = 45/74 (60%), Gaps = 8/74 (10%)

Query: 23  EEEKDPDAQKKEEE------RQEALRQQEEERKAKHARMEAEREKVRQQ--IRDKYGLKK 74
           EEEK  + +K++E+      ++E +R+QEE+ + +  +M  + EK+ +Q  IR++   ++
Sbjct: 415 EEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQE 474

Query: 75  KEEKEAEEKAALEQ 88
           +EE   +E+   EQ
Sbjct: 475 QEEMWRQEEKIHEQ 488



 Score = 37.0 bits (84), Expect = 0.005
 Identities = 29/97 (29%), Positives = 52/97 (53%), Gaps = 15/97 (15%)

Query: 25  EKDPDAQKKEE---ERQEALRQQEEERKAKHARMEAEREKVRQQ--IRDKYGLKKKEEKE 79
           EK+   +++EE   E++E +R+QEE    K  ++    EK+ +Q  IR++   +++EEK 
Sbjct: 360 EKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKI 419

Query: 80  AEEKAALEQPCEGSLTRPKKAIPAGCGDEEEEEEESI 116
            E++   EQ  E  + R ++ I         E+EE I
Sbjct: 420 REQEKRQEQ--EAKMWRQEEKI--------REQEEKI 446



 Score = 36.2 bits (82), Expect = 0.008
 Identities = 19/65 (29%), Positives = 40/65 (61%), Gaps = 2/65 (3%)

Query: 24  EEKDPDAQKKEEERQEALRQQEEERKAKHARMEAEREKVRQQIRDKYGLKKKEEKEAEEK 83
           EEK  + ++K  E++E +R+QEE+ + +   M  + EK+R+Q  ++   +K+E+   +E+
Sbjct: 313 EEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQ--EEMMWEKEEKMRRQEE 370

Query: 84  AALEQ 88
              E+
Sbjct: 371 MMWEK 375



 Score = 36.2 bits (82), Expect = 0.008
 Identities = 26/92 (28%), Positives = 52/92 (56%), Gaps = 11/92 (11%)

Query: 23  EEEKDPDAQKKEEERQEALRQQEEERKAKHARMEAEREKVRQQIRDKYGLKKKEEKEAEE 82
           +EEK  + ++K +E++E +R+QEE+ +        E+E++ Q+  +K G ++++  E EE
Sbjct: 610 QEEKIREQEEKIQEQEEKIREQEEKIR--------EQEEMTQEQEEKMGEQEEKMCEQEE 661

Query: 83  KAALEQPCEGSLTRPKKAIPAGCGDEEEEEEE 114
           K    Q  E ++ R ++ I        E+EE+
Sbjct: 662 KM---QEQEETMWRQEEKIREQEKKIREQEEK 690



 Score = 35.4 bits (80), Expect = 0.014
 Identities = 25/91 (27%), Positives = 50/91 (54%), Gaps = 3/91 (3%)

Query: 23  EEEKDPDAQKKEEERQEALRQQEEERKAKHARMEAEREKVRQQIRDKYGLKKKEEKEAEE 82
           EEEK  + + K   ++E +R+QEE+   +  ++  + EK RQ+  +K  + K+EEK  E+
Sbjct: 561 EEEKRQEQEDKMWRQEEKIREQEEKVWRQEEKIREQEEK-RQEQEEK--MWKQEEKIREQ 617

Query: 83  KAALEQPCEGSLTRPKKAIPAGCGDEEEEEE 113
           +  +++  E    + +K        +E+EE+
Sbjct: 618 EEKIQEQEEKIREQEEKIREQEEMTQEQEEK 648



 Score = 35.4 bits (80), Expect = 0.014
 Identities = 19/72 (26%), Positives = 42/72 (58%), Gaps = 4/72 (5%)

Query: 14  KDMGKMLGGEEEKDPDAQKKEEERQEALRQQEEERKAKHARMEAEREKVRQQ----IRDK 69
           ++  K +  +EEK  + ++  +E++E + +QEE+   +  +M+ + EK+R+Q       +
Sbjct: 678 REQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQE 737

Query: 70  YGLKKKEEKEAE 81
             L+++EEK  E
Sbjct: 738 VRLRQQEEKMQE 749



 Score = 35.0 bits (79), Expect = 0.018
 Identities = 24/77 (31%), Positives = 46/77 (59%), Gaps = 13/77 (16%)

Query: 25  EKDPDAQKKEE---ERQEALRQQEE---ERKAKHARME----AEREKVR---QQIRDKYG 71
           EK+   +++EE   E++E +R+QEE   E++ K  R E     + EK+R   +++ ++  
Sbjct: 346 EKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEK 405

Query: 72  LKKKEEKEAEEKAALEQ 88
           ++++EEK  EE+   EQ
Sbjct: 406 IREQEEKRQEEEKIREQ 422



 Score = 35.0 bits (79), Expect = 0.018
 Identities = 19/66 (28%), Positives = 39/66 (59%), Gaps = 4/66 (6%)

Query: 23  EEEKDPDAQKKEEERQEALRQQEEERKAKHARMEAEREKVRQQIRDKYGLKKKEEKEAEE 82
           +EEK    ++K   ++E +R+QEE+ + +  +M  + EK+R+Q      + ++EEK  E+
Sbjct: 501 QEEKIRKQEEKVWRQEEKIREQEEKIREQEEKMWRQEEKIREQEE----MWREEEKMHEQ 556

Query: 83  KAALEQ 88
           +   E+
Sbjct: 557 EKIWEE 562



 Score = 34.3 bits (77), Expect = 0.031
 Identities = 20/70 (28%), Positives = 41/70 (58%), Gaps = 4/70 (5%)

Query: 23  EEEKDPDAQKKEEERQEALRQQEEERKAKHARMEAEREKVRQQ----IRDKYGLKKKEEK 78
           E+E+    ++K  E++E +R+QEE+   +  ++  + EK+R+Q     R +  ++++EE 
Sbjct: 487 EQEEIWRQKEKMHEQEEKIRKQEEKVWRQEEKIREQEEKIREQEEKMWRQEEKIREQEEM 546

Query: 79  EAEEKAALEQ 88
             EE+   EQ
Sbjct: 547 WREEEKMHEQ 556



 Score = 33.9 bits (76), Expect = 0.040
 Identities = 22/66 (33%), Positives = 40/66 (60%), Gaps = 4/66 (6%)

Query: 18  KMLGGEEEKDPDAQKKEEERQEALRQQEEERKAKHARMEAEREKVRQQIRDKYGLKKKEE 77
           +M+  +EEK  + ++K  E QE +R+QEE+R+ +    E E+   RQ+   K   ++++ 
Sbjct: 384 EMMWEKEEKIRELEEKMHE-QEKIREQEEKRQEEEKIREQEK---RQEQEAKMWRQEEKI 439

Query: 78  KEAEEK 83
           +E EEK
Sbjct: 440 REQEEK 445



 Score = 33.5 bits (75), Expect = 0.052
 Identities = 25/75 (33%), Positives = 45/75 (60%), Gaps = 10/75 (13%)

Query: 23  EEEKDPDAQKKEEERQEALRQQE--EERKAKHARME----AEREKVRQQIRDKYGLKKK- 75
           E+EK  + ++K +E +E +R+QE  +E++AK  R E     + EK+R+Q +  +  ++K 
Sbjct: 402 EQEKIREQEEKRQE-EEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKI 460

Query: 76  --EEKEAEEKAALEQ 88
             +EK  EE+   EQ
Sbjct: 461 HEQEKIREEEKRQEQ 475



 Score = 33.5 bits (75), Expect = 0.052
 Identities = 20/65 (30%), Positives = 39/65 (60%), Gaps = 5/65 (7%)

Query: 23  EEEKDPDAQKKEEE----RQEALRQQEEERKAKHARMEAEREKVRQQIRDKYGLKKKEEK 78
           E+EK  + +K++E+    RQE    ++EE   +  +M  + EK+R+Q  +K   ++++ +
Sbjct: 462 EQEKIREEEKRQEQEEMWRQEEKIHEQEEIWRQKEKMHEQEEKIRKQ-EEKVWRQEEKIR 520

Query: 79  EAEEK 83
           E EEK
Sbjct: 521 EQEEK 525



 Score = 33.1 bits (74), Expect = 0.069
 Identities = 29/104 (27%), Positives = 54/104 (51%), Gaps = 13/104 (12%)

Query: 23  EEEKDPDAQKKEEERQEALRQQEE---ERKAKHARMEA----EREKVRQQ---IRDKYGL 72
           +EEK  + ++K  E++E +R+QEE   E++ K  R E     + EK+R+Q   + +K   
Sbjct: 319 QEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEK 378

Query: 73  KKKEEKEAEEKAALEQPCEGSLTRPKKAIPAGCGDEEEEEEESI 116
            +++E+   EK    +  E  +   +K       +E+ +EEE I
Sbjct: 379 MRRQEEMMWEKEEKIRELEEKMHEQEKIREQ---EEKRQEEEKI 419



 Score = 32.3 bits (72), Expect = 0.12
 Identities = 17/66 (25%), Positives = 41/66 (62%), Gaps = 2/66 (3%)

Query: 23  EEEKDPDAQKKEEERQEALRQQEEERKAKHARMEAEREKVRQQIRDKYGLKKKEEKEAEE 82
           +EEK    ++K +E +E +++QEE+ + +  ++  + EK+R+Q  ++   +K+E+   +E
Sbjct: 298 QEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQ--EEMMWEKEEKMRRQE 355

Query: 83  KAALEQ 88
           +   E+
Sbjct: 356 EMMWEK 361



 Score = 32.0 bits (71), Expect = 0.15
 Identities = 19/65 (29%), Positives = 37/65 (56%), Gaps = 6/65 (9%)

Query: 23  EEEKDPDAQKKEEERQEALRQQ----EEERKAKHARMEAEREKVRQQIRDKYGLKKKEEK 78
           +EEK  + +KK   ++E + +Q    EEE++ +   M  + EK+ +Q  ++   +K++  
Sbjct: 442 QEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIHEQ--EEIWRQKEKMH 499

Query: 79  EAEEK 83
           E EEK
Sbjct: 500 EQEEK 504



 Score = 31.2 bits (69), Expect = 0.26
 Identities = 24/94 (25%), Positives = 50/94 (53%), Gaps = 4/94 (4%)

Query: 23  EEEKDPDAQKKEEERQEALRQQEEERKAKHARMEAE--REKVRQQIRDKYGLKKKEEKEA 80
           +EE   + ++K  E +E + +QE+ R+ +  R E E  RE+ ++Q ++    +++E+   
Sbjct: 382 QEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIRE 441

Query: 81  EEKAALEQPCEGSLTRPKKAIPAGCGDEEEEEEE 114
           +E+   EQ  E  + R ++ I       EEE+ +
Sbjct: 442 QEEKIREQ--EKKMWRQEEKIHEQEKIREEEKRQ 473



 Score = 30.8 bits (68), Expect = 0.34
 Identities = 21/78 (26%), Positives = 38/78 (48%), Gaps = 17/78 (21%)

Query: 23  EEEKDPDAQKKEEERQEALRQQEE-----------------ERKAKHARMEAEREKVRQQ 65
           +EEK    ++K  E++E +R+QEE                 E +  H + +   E+ RQ+
Sbjct: 508 QEEKVWRQEEKIREQEEKIREQEEKMWRQEEKIREQEEMWREEEKMHEQEKIWEEEKRQE 567

Query: 66  IRDKYGLKKKEEKEAEEK 83
             DK   ++++ +E EEK
Sbjct: 568 QEDKMWRQEEKIREQEEK 585



 Score = 30.8 bits (68), Expect = 0.34
 Identities = 23/94 (24%), Positives = 51/94 (54%), Gaps = 6/94 (6%)

Query: 23  EEEKDPDAQKKEEERQEALRQ--QEEERKAKHARMEAEREKVRQQIRDKYGLKKKEEKEA 80
           E+ ++ +   +EEE+     +  +EE+R+ +  +M  + EK+R+Q  +K   ++++ +E 
Sbjct: 538 EKIREQEEMWREEEKMHEQEKIWEEEKRQEQEDKMWRQEEKIREQ-EEKVWRQEEKIREQ 596

Query: 81  EEKAALEQPCEGSLTRPKKAIPAGCGDEEEEEEE 114
           EEK    Q  E  + + ++ I       +E+EE+
Sbjct: 597 EEK---RQEQEEKMWKQEEKIREQEEKIQEQEEK 627



 Score = 30.4 bits (67), Expect = 0.44
 Identities = 23/78 (29%), Positives = 37/78 (47%), Gaps = 1/78 (1%)

Query: 6   KQALGGATKDMGKMLGGEEEKDPDAQKKEEERQEALRQQEEERKAKHARMEAEREKVRQQ 65
           +Q L      +GK L     K   AQ +E E    L QQ+EE+  +      E E+  Q+
Sbjct: 260 QQQLQAEADHLGKELQSVSAK-LQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQE 318

Query: 66  IRDKYGLKKKEEKEAEEK 83
             +K   ++++ +E EEK
Sbjct: 319 QEEKIREQEEKIREQEEK 336



 Score = 28.5 bits (62), Expect = 1.7
 Identities = 17/71 (23%), Positives = 37/71 (52%)

Query: 18  KMLGGEEEKDPDAQKKEEERQEALRQQEEERKAKHARMEAEREKVRQQIRDKYGLKKKEE 77
           KM   EE+     +K  E+ ++  RQ+E+  + +  R E +R++  +  R +  + ++EE
Sbjct: 431 KMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIHEQEE 490

Query: 78  KEAEEKAALEQ 88
              +++   EQ
Sbjct: 491 IWRQKEKMHEQ 501


>gi|115298682 HBxAg transactivated protein 2 [Homo sapiens]
          Length = 2817

 Score = 43.1 bits (100), Expect = 7e-05
 Identities = 32/114 (28%), Positives = 59/114 (51%), Gaps = 1/114 (0%)

Query: 1   MDFVMKQALGGATKDMGKMLGGEEEKDPDAQKKEEERQEALRQQEEERKAKHARMEAERE 60
           M+   K A     K + + LG  E++    + +E ER++   +++E  K +    E ERE
Sbjct: 473 MEEQRKAACAEKLKRLDEKLGILEKQPSPEEIREREREKEREREKELEKEQEQEREKERE 532

Query: 61  KVRQQIRDK-YGLKKKEEKEAEEKAALEQPCEGSLTRPKKAIPAGCGDEEEEEE 113
           K R++ ++K   L+K++EK+ E +   +Q  E  L R K+        +E+E+E
Sbjct: 533 KDRERQQEKEKELEKEQEKQREMEKERKQEKEKELERQKEKEKELQKMKEQEKE 586



 Score = 42.7 bits (99), Expect = 9e-05
 Identities = 25/84 (29%), Positives = 47/84 (55%), Gaps = 8/84 (9%)

Query: 23  EEEKDPDAQKKEEERQEALRQQEEERKA-KHARMEAEREKVRQQIRDKYGLKKKE----- 76
           E E++ + +K++E+ +E  R+++ ER+  K   +E E+EK R+  +++   K+KE     
Sbjct: 512 EREREKELEKEQEQEREKEREKDRERQQEKEKELEKEQEKQREMEKERKQEKEKELERQK 571

Query: 77  --EKEAEEKAALEQPCEGSLTRPK 98
             EKE ++    E+ CE    R K
Sbjct: 572 EKEKELQKMKEQEKECELEKEREK 595



 Score = 42.7 bits (99), Expect = 9e-05
 Identities = 29/101 (28%), Positives = 59/101 (58%), Gaps = 7/101 (6%)

Query: 23  EEEKDPDAQKKEEERQEALRQQEEERK-AKHARMEAEREKVRQQIRDKYGLKKKEEKEAE 81
           E EK+ + ++++E  ++  RQQE+E++  K    + E EK R+Q ++K  L++++EKE E
Sbjct: 518 ELEKEQEQEREKEREKDRERQQEKEKELEKEQEKQREMEKERKQEKEK-ELERQKEKEKE 576

Query: 82  EKAALEQPCEGSLTRPKKAIPAGCGDEEEEEEESILDTVLK 122
            +   EQ  E  L + ++ +     +E+ E  E  L+ +++
Sbjct: 577 LQKMKEQEKECELEKEREKL-----EEKIEPREPNLEPMVE 612



 Score = 42.7 bits (99), Expect = 9e-05
 Identities = 33/98 (33%), Positives = 56/98 (57%), Gaps = 10/98 (10%)

Query: 23  EEEKDPDAQKKEEERQEALRQQEEERK-AKHARMEAEREKVRQQIRDKYGLKKKE-EKEA 80
           E+E++ D ++++E+ +E  ++QE++R+  K  + E E+E  RQ+ ++K   K KE EKE 
Sbjct: 528 EKEREKDRERQQEKEKELEKEQEKQREMEKERKQEKEKELERQKEKEKELQKMKEQEKEC 587

Query: 81  E---EKAALE---QPCEGSLTR--PKKAIPAGCGDEEE 110
           E   E+  LE   +P E +L     K+     C  EEE
Sbjct: 588 ELEKEREKLEEKIEPREPNLEPMVEKQESENSCNKEEE 625



 Score = 38.9 bits (89), Expect = 0.001
 Identities = 25/94 (26%), Positives = 48/94 (51%), Gaps = 3/94 (3%)

Query: 23  EEEKDPDAQKKEEERQEALRQQEEER---KAKHARMEAEREKVRQQIRDKYGLKKKEEKE 79
           EE ++ + +K+ E  +E  ++QE+ER   + K    + E+EK  ++ ++K    +KE K+
Sbjct: 502 EEIREREREKEREREKELEKEQEQEREKEREKDRERQQEKEKELEKEQEKQREMEKERKQ 561

Query: 80  AEEKAALEQPCEGSLTRPKKAIPAGCGDEEEEEE 113
            +EK    Q  +    +  K     C  E+E E+
Sbjct: 562 EKEKELERQKEKEKELQKMKEQEKECELEKEREK 595



 Score = 36.2 bits (82), Expect = 0.008
 Identities = 21/72 (29%), Positives = 42/72 (58%), Gaps = 6/72 (8%)

Query: 14  KDMGKMLGGEEEKDPDAQKKEEERQEALRQQEEERKAKHARMEAEREKVRQQIRDKY-GL 72
           ++M K    E+EK+ + QK++E+  + +++QE+E       +E EREK+ ++I  +   L
Sbjct: 553 REMEKERKQEKEKELERQKEKEKELQKMKEQEKE-----CELEKEREKLEEKIEPREPNL 607

Query: 73  KKKEEKEAEEKA 84
           +   EK+  E +
Sbjct: 608 EPMVEKQESENS 619



 Score = 35.4 bits (80), Expect = 0.014
 Identities = 22/78 (28%), Positives = 42/78 (53%), Gaps = 5/78 (6%)

Query: 18  KMLGGEEEKDPDAQK-KEEERQEALRQQEEE----RKAKHARMEAEREKVRQQIRDKYGL 72
           K L  E+EK  + +K +++E+++ L +Q+E+    +K K    E E EK R+++ +K   
Sbjct: 543 KELEKEQEKQREMEKERKQEKEKELERQKEKEKELQKMKEQEKECELEKEREKLEEKIEP 602

Query: 73  KKKEEKEAEEKAALEQPC 90
           ++   +   EK   E  C
Sbjct: 603 REPNLEPMVEKQESENSC 620



 Score = 29.3 bits (64), Expect = 0.99
 Identities = 27/113 (23%), Positives = 52/113 (46%), Gaps = 28/113 (24%)

Query: 23  EEEKDPDAQKKEEERQEA----------LRQQEEERKAKHARMEAEREKVRQQIRDKYGL 72
           ++  D D   K+  RQ++           R++EEER+ +  R  A  EK+++ + +K G+
Sbjct: 436 QQVADEDEIWKQRRRQQSEISAAVERARKRREEEERRMEEQRKAACAEKLKR-LDEKLGI 494

Query: 73  KKKE-----------EKEAEEKAALEQPCEGSLTRPKKAIPAGCGDEEEEEEE 114
            +K+           EKE E +  LE+  E    + ++       D E ++E+
Sbjct: 495 LEKQPSPEEIREREREKEREREKELEKEQEQEREKEREK------DRERQQEK 541


>gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo
           sapiens]
          Length = 668

 Score = 42.4 bits (98), Expect = 1e-04
 Identities = 26/101 (25%), Positives = 60/101 (59%), Gaps = 8/101 (7%)

Query: 14  KDMGKMLGGEEEKDPDAQKKEEERQEALRQQEEERKAKHARMEAEREKVRQQIRDKYGLK 73
           ++  +M+  +EEK  + ++K +E QE +R+QEE+ + +  ++  ++EK+R+Q   +  + 
Sbjct: 540 REQEEMMQEQEEKMGEQEEKMQE-QEKMRRQEEKIREQEEKIREQKEKIREQ---EEKIW 595

Query: 74  KKEEKEAEEKAALEQPCEGSLTRPKKAIPAGCGDEEEEEEE 114
           ++EEK  E++  +++  E    + +K     C  EE+ +E+
Sbjct: 596 EQEEKIREQEEMMQEQEEKMWEQEEKM----CEQEEKMQEQ 632



 Score = 40.4 bits (93), Expect = 4e-04
 Identities = 25/94 (26%), Positives = 53/94 (56%), Gaps = 3/94 (3%)

Query: 23  EEEKDPDAQKKEEERQEALRQQEEERKAKHARMEAEREKVRQQ---IRDKYGLKKKEEKE 79
           +EEK  + ++K  E++E +R+QEE  + +  +M  + EK+++Q    R +  ++++EEK 
Sbjct: 521 QEEKIREQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMQEQEKMRRQEEKIREQEEKI 580

Query: 80  AEEKAALEQPCEGSLTRPKKAIPAGCGDEEEEEE 113
            E+K  + +  E    + +K        +E+EE+
Sbjct: 581 REQKEKIREQEEKIWEQEEKIREQEEMMQEQEEK 614



 Score = 38.9 bits (89), Expect = 0.001
 Identities = 25/95 (26%), Positives = 53/95 (55%), Gaps = 9/95 (9%)

Query: 24  EEKDPDAQKKEEERQEALRQQEEERKAKHARMEAEREKVRQQ----IRDKYGLKKKEEKE 79
           E+++   QK++   QE +R+QEE+   +  +M  + EK+R+Q     R +  ++++EEK 
Sbjct: 473 EQEEIWRQKEKMHEQEKIRKQEEKVWRQEEKMHDQEEKIREQEEKMWRQEEKIREQEEKI 532

Query: 80  AEEKAALEQPCEGSLTRPKKAIPAGCGDEEEEEEE 114
            E++  + +  E    + +K      G++EE+ +E
Sbjct: 533 REQEEKIREQEEMMQEQEEK-----MGEQEEKMQE 562



 Score = 38.9 bits (89), Expect = 0.001
 Identities = 18/66 (27%), Positives = 43/66 (65%), Gaps = 3/66 (4%)

Query: 23  EEEKDPDAQKKEEERQEALRQQEEERKAKHARMEAEREKVRQQIRDKYGLKKKEEKEAEE 82
           +EEK  D ++K  E++E + +QEE+ + +  ++  + EK+R+Q   +  ++++EEK  E+
Sbjct: 500 QEEKMHDQEEKIREQEEKMWRQEEKIREQEEKIREQEEKIREQ---EEMMQEQEEKMGEQ 556

Query: 83  KAALEQ 88
           +  +++
Sbjct: 557 EEKMQE 562



 Score = 38.5 bits (88), Expect = 0.002
 Identities = 20/80 (25%), Positives = 48/80 (60%), Gaps = 3/80 (3%)

Query: 15  DMGKMLGGEEEKDPDAQKKEEERQEALRQQEEERKAKHARMEAEREKVRQQ---IRDKYG 71
           D  + +  +EEK    ++K  E++E +R+QEE+ + +   M+ + EK+ +Q   ++++  
Sbjct: 506 DQEEKIREQEEKMWRQEEKIREQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMQEQEK 565

Query: 72  LKKKEEKEAEEKAALEQPCE 91
           ++++EEK  E++  + +  E
Sbjct: 566 MRRQEEKIREQEEKIREQKE 585



 Score = 38.1 bits (87), Expect = 0.002
 Identities = 22/74 (29%), Positives = 45/74 (60%), Gaps = 8/74 (10%)

Query: 23  EEEKDPDAQKKEEE------RQEALRQQEEERKAKHARMEAEREKVRQQ--IRDKYGLKK 74
           EEEK  + +K++E+      ++E +R+QEE+ + +  +M  + EK+ +Q  IR++   ++
Sbjct: 401 EEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQE 460

Query: 75  KEEKEAEEKAALEQ 88
           +EE   +E+   EQ
Sbjct: 461 QEEMWRQEEKIREQ 474



 Score = 36.6 bits (83), Expect = 0.006
 Identities = 20/69 (28%), Positives = 41/69 (59%), Gaps = 4/69 (5%)

Query: 23  EEEKDPDAQKKEEERQEALRQQEEERKAKHARMEAEREKVRQQ----IRDKYGLKKKEEK 78
           +EEK  + ++  +E++E + +QEE+   +  +M+ + EK+R+Q       +  L+++EEK
Sbjct: 597 QEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQEEK 656

Query: 79  EAEEKAALE 87
             E +  LE
Sbjct: 657 MQEHQEHLE 665



 Score = 35.8 bits (81), Expect = 0.011
 Identities = 26/96 (27%), Positives = 50/96 (52%), Gaps = 6/96 (6%)

Query: 24  EEKDPDAQKKEEERQEALRQQEEERKAKHARMEAEREKVRQQ---IRDKYGLKKKEEKEA 80
           EEK  + ++K  E++E +R+QEE+ + +   M  + EK+R+Q   + +K    ++ E+  
Sbjct: 313 EEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRLEEMM 372

Query: 81  EEKAALEQPCEGSLTRPKKAIPAGCGDEEEEEEESI 116
            EK    +  E  +   +K       +E+ +EEE I
Sbjct: 373 WEKEEKIRELEEKMHEQEKIREQ---EEKRQEEEKI 405



 Score = 34.7 bits (78), Expect = 0.024
 Identities = 21/67 (31%), Positives = 41/67 (61%), Gaps = 6/67 (8%)

Query: 23  EEEKDPDAQKKEEERQEALRQQEE---ERKAKHARMEA---EREKVRQQIRDKYGLKKKE 76
           +EEK  + ++K  E++E +R+QEE   E++ K  R E    E+E+  +++ +    K+++
Sbjct: 319 QEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRLEEMMWEKEEK 378

Query: 77  EKEAEEK 83
            +E EEK
Sbjct: 379 IRELEEK 385



 Score = 34.7 bits (78), Expect = 0.024
 Identities = 23/76 (30%), Positives = 45/76 (59%), Gaps = 10/76 (13%)

Query: 23  EEEKDPDAQKKEEERQEALRQQEE---ERKAKHARME----AEREKVR---QQIRDKYGL 72
           +EEK    ++   E++E +R+QEE   E++ K  R+E     + EK+R   +++ ++  +
Sbjct: 333 QEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRLEEMMWEKEEKIRELEEKMHEQEKI 392

Query: 73  KKKEEKEAEEKAALEQ 88
           +++EEK  EE+   EQ
Sbjct: 393 REQEEKRQEEEKIREQ 408



 Score = 34.7 bits (78), Expect = 0.024
 Identities = 17/66 (25%), Positives = 40/66 (60%), Gaps = 3/66 (4%)

Query: 23  EEEKDPDAQKKEEERQEALRQQEEERKAKHARMEAEREKVRQQIRDKYGLKKKEEKEAEE 82
           E+EK    ++K   ++E +  QEE+ + +  +M  + EK+R+Q   +  ++++EEK  E+
Sbjct: 486 EQEKIRKQEEKVWRQEEKMHDQEEKIREQEEKMWRQEEKIREQ---EEKIREQEEKIREQ 542

Query: 83  KAALEQ 88
           +  +++
Sbjct: 543 EEMMQE 548



 Score = 34.3 bits (77), Expect = 0.031
 Identities = 28/97 (28%), Positives = 51/97 (52%), Gaps = 15/97 (15%)

Query: 25  EKDPDAQKKEE---ERQEALRQQEEERKAKHARMEAEREKVRQQ--IRDKYGLKKKEEKE 79
           EK+   +++EE   E++E +R+ EE    K  ++    EK+ +Q  IR++   +++EEK 
Sbjct: 346 EKEEKMRRQEEMMWEKEEKMRRLEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKI 405

Query: 80  AEEKAALEQPCEGSLTRPKKAIPAGCGDEEEEEEESI 116
            E++   EQ  E  + R ++ I         E+EE I
Sbjct: 406 REQEKRQEQ--EAKMWRQEEKI--------REQEEKI 432



 Score = 33.9 bits (76), Expect = 0.040
 Identities = 22/66 (33%), Positives = 40/66 (60%), Gaps = 4/66 (6%)

Query: 18  KMLGGEEEKDPDAQKKEEERQEALRQQEEERKAKHARMEAEREKVRQQIRDKYGLKKKEE 77
           +M+  +EEK  + ++K  E QE +R+QEE+R+ +    E E+   RQ+   K   ++++ 
Sbjct: 370 EMMWEKEEKIRELEEKMHE-QEKIREQEEKRQEEEKIREQEK---RQEQEAKMWRQEEKI 425

Query: 78  KEAEEK 83
           +E EEK
Sbjct: 426 REQEEK 431



 Score = 33.9 bits (76), Expect = 0.040
 Identities = 21/61 (34%), Positives = 40/61 (65%), Gaps = 3/61 (4%)

Query: 23  EEEKDPDAQKKEEERQEALRQQEEERKAKHARMEAEREKVRQQIRDKYGLKKKEEKEAEE 82
           E+EK  + ++K +E +E +R+QE+ R+ + A+M  + EK+R+Q  +K   ++K+    EE
Sbjct: 388 EQEKIREQEEKRQE-EEKIREQEK-RQEQEAKMWRQEEKIREQ-EEKIREQEKKMWRQEE 444

Query: 83  K 83
           K
Sbjct: 445 K 445



 Score = 33.9 bits (76), Expect = 0.040
 Identities = 18/61 (29%), Positives = 39/61 (63%), Gaps = 1/61 (1%)

Query: 23  EEEKDPDAQKKEEERQEALRQQEEERKAKHARMEAEREKVRQQIRDKYGLKKKEEKEAEE 82
           +EEK  + ++K  E++E + +QEE+ + +   M+ + EK+ +Q  +K   ++++ +E EE
Sbjct: 576 QEEKIREQKEKIREQEEKIWEQEEKIREQEEMMQEQEEKMWEQ-EEKMCEQEEKMQEQEE 634

Query: 83  K 83
           K
Sbjct: 635 K 635



 Score = 33.9 bits (76), Expect = 0.040
 Identities = 19/70 (27%), Positives = 41/70 (58%), Gaps = 4/70 (5%)

Query: 23  EEEKDPDAQKKEEERQEALRQQEEERKAKHARMEAEREKVRQQ----IRDKYGLKKKEEK 78
           ++EK  + ++K  E++E +R+QEE  + +  +M  + EK+ +Q       +  ++++EEK
Sbjct: 583 QKEKIREQEEKIWEQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEK 642

Query: 79  EAEEKAALEQ 88
             E++  L Q
Sbjct: 643 MWEQEVRLRQ 652



 Score = 33.1 bits (74), Expect = 0.069
 Identities = 21/77 (27%), Positives = 44/77 (57%), Gaps = 6/77 (7%)

Query: 18  KMLGGEEEKDPDAQKKEEER---QEALRQQEEERKAKHARMEAEREKVRQQIRDKYGLKK 74
           KM   E+ ++ + +++EEE+   QE  ++QE +   +  ++  + EK+R+Q +  +  ++
Sbjct: 385 KMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEE 444

Query: 75  K---EEKEAEEKAALEQ 88
           K   +EK  EE+   EQ
Sbjct: 445 KIHEQEKIREEEKRQEQ 461



 Score = 33.1 bits (74), Expect = 0.069
 Identities = 16/66 (24%), Positives = 40/66 (60%)

Query: 23  EEEKDPDAQKKEEERQEALRQQEEERKAKHARMEAEREKVRQQIRDKYGLKKKEEKEAEE 82
           +EEK  + +KK   ++E + +QE+ R+ +  + + E  +  ++IR++  + +++EK  E+
Sbjct: 428 QEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKMHEQ 487

Query: 83  KAALEQ 88
           +   +Q
Sbjct: 488 EKIRKQ 493



 Score = 32.3 bits (72), Expect = 0.12
 Identities = 17/66 (25%), Positives = 41/66 (62%), Gaps = 2/66 (3%)

Query: 23  EEEKDPDAQKKEEERQEALRQQEEERKAKHARMEAEREKVRQQIRDKYGLKKKEEKEAEE 82
           +EEK    ++K +E +E +++QEE+ + +  ++  + EK+R+Q  ++   +K+E+   +E
Sbjct: 298 QEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQ--EEMMWEKEEKMRRQE 355

Query: 83  KAALEQ 88
           +   E+
Sbjct: 356 EMMWEK 361



 Score = 30.4 bits (67), Expect = 0.44
 Identities = 23/78 (29%), Positives = 37/78 (47%), Gaps = 1/78 (1%)

Query: 6   KQALGGATKDMGKMLGGEEEKDPDAQKKEEERQEALRQQEEERKAKHARMEAEREKVRQQ 65
           +Q L      +GK L     K   AQ +E E    L QQ+EE+  +      E E+  Q+
Sbjct: 260 QQQLQAEADHLGKELQSVSAK-LQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQE 318

Query: 66  IRDKYGLKKKEEKEAEEK 83
             +K   ++++ +E EEK
Sbjct: 319 QEEKIREQEEKIREQEEK 336



 Score = 30.0 bits (66), Expect = 0.58
 Identities = 20/73 (27%), Positives = 44/73 (60%), Gaps = 5/73 (6%)

Query: 14  KDMGKMLGGEEEKDPDAQK-KEEERQEALRQQEEERKAKHARMEAEREKVRQQIRDKYGL 72
           ++  K +  +EEK  + +K +EEE+++   Q+E  R+ +  R + E  + ++++ ++  +
Sbjct: 433 REQEKKMWRQEEKIHEQEKIREEEKRQ--EQEEMWRQEEKIREQEEIWRQKEKMHEQEKI 490

Query: 73  KKKEEK--EAEEK 83
           +K+EEK    EEK
Sbjct: 491 RKQEEKVWRQEEK 503



 Score = 30.0 bits (66), Expect = 0.58
 Identities = 20/66 (30%), Positives = 40/66 (60%), Gaps = 8/66 (12%)

Query: 23  EEEKDPDAQKKEEE-----RQEALRQQEEERKAKHARMEAEREKVRQQIRDKYGLKKKEE 77
           E+EK  + +K++E+     ++E +R+QEE  + K    E  +EK+R+Q  +K   ++++ 
Sbjct: 448 EQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKMHE--QEKIRKQ-EEKVWRQEEKM 504

Query: 78  KEAEEK 83
            + EEK
Sbjct: 505 HDQEEK 510



 Score = 29.6 bits (65), Expect = 0.76
 Identities = 17/71 (23%), Positives = 38/71 (53%)

Query: 18  KMLGGEEEKDPDAQKKEEERQEALRQQEEERKAKHARMEAEREKVRQQIRDKYGLKKKEE 77
           KM   EE+     +K  E+ ++  RQ+E+  + +  R E +R++  +  R +  ++++EE
Sbjct: 417 KMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEE 476

Query: 78  KEAEEKAALEQ 88
              +++   EQ
Sbjct: 477 IWRQKEKMHEQ 487



 Score = 29.3 bits (64), Expect = 0.99
 Identities = 17/65 (26%), Positives = 41/65 (63%), Gaps = 4/65 (6%)

Query: 18  KMLGGEEEKDPDAQKKEEERQEALRQQEEE-RKAKHARMEAEREKVRQQIRDKYGLKKKE 76
           +M+  +EEK    ++   E++E +R+ EE+  + +  R + E+ +  ++IR++   +K++
Sbjct: 356 EMMWEKEEKMRRLEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQ---EKRQ 412

Query: 77  EKEAE 81
           E+EA+
Sbjct: 413 EQEAK 417


>gi|195927037 DNA (cytosine-5-)-methyltransferase 1 isoform a [Homo
           sapiens]
          Length = 1632

 Score = 42.4 bits (98), Expect = 1e-04
 Identities = 30/92 (32%), Positives = 43/92 (46%), Gaps = 11/92 (11%)

Query: 21  GGEEEKDPDAQKKEEERQEALRQQEEERKAKHARMEAEREKVRQQIRDKYGLKKKEEKE- 79
           G + ++D D  +K+E++    R Q ++  AK    E E EKV  QI D+    +KEEK  
Sbjct: 285 GVQADEDEDGDEKDEKKH---RSQPKDLAAKRRPEEKEPEKVNPQISDEKDEDEKEEKRR 341

Query: 80  -------AEEKAALEQPCEGSLTRPKKAIPAG 104
                   E+K A  +    S T P K I  G
Sbjct: 342 KTTPKEPTEKKMARAKTVMNSKTHPPKCIQCG 373



 Score = 34.3 bits (77), Expect = 0.031
 Identities = 27/97 (27%), Positives = 43/97 (44%), Gaps = 6/97 (6%)

Query: 21  GGEEEKDPDAQKKEEERQEALRQQEEERKAKHARMEAEREKVR---QQIRDKYGLKKKEE 77
           G   EK+ +  +KEE+R   LR Q +E   K    E    + R   Q   D+ G +K E+
Sbjct: 244 GTRTEKEEERDEKEEKR---LRSQTKEPTPKQKLKEEPDREARAGVQADEDEDGDEKDEK 300

Query: 78  KEAEEKAALEQPCEGSLTRPKKAIPAGCGDEEEEEEE 114
           K   +   L          P+K  P    +++E+E+E
Sbjct: 301 KHRSQPKDLAAKRRPEEKEPEKVNPQISDEKDEDEKE 337



 Score = 31.6 bits (70), Expect = 0.20
 Identities = 21/105 (20%), Positives = 52/105 (49%), Gaps = 13/105 (12%)

Query: 22  GEEEKDPDAQKKEEERQEALRQQEEERKAKHARMEAEREKVRQQI------RDKYGLKKK 75
           G  ++ P  + +  +  E+++++++++  K  R+ + RE+V + +      R K G + +
Sbjct: 190 GPAKRKPQEESERAKSDESIKEEDKDQDEKRRRVTS-RERVARPLPAEEPERAKSGTRTE 248

Query: 76  EEKEAEEKAALEQPCEGSLTRPKKAI------PAGCGDEEEEEEE 114
           +E+E +EK       +     PK+ +       A  G + +E+E+
Sbjct: 249 KEEERDEKEEKRLRSQTKEPTPKQKLKEEPDREARAGVQADEDED 293


>gi|4503351 DNA (cytosine-5-)-methyltransferase 1 isoform b [Homo
           sapiens]
          Length = 1616

 Score = 42.4 bits (98), Expect = 1e-04
 Identities = 30/92 (32%), Positives = 43/92 (46%), Gaps = 11/92 (11%)

Query: 21  GGEEEKDPDAQKKEEERQEALRQQEEERKAKHARMEAEREKVRQQIRDKYGLKKKEEKE- 79
           G + ++D D  +K+E++    R Q ++  AK    E E EKV  QI D+    +KEEK  
Sbjct: 269 GVQADEDEDGDEKDEKKH---RSQPKDLAAKRRPEEKEPEKVNPQISDEKDEDEKEEKRR 325

Query: 80  -------AEEKAALEQPCEGSLTRPKKAIPAG 104
                   E+K A  +    S T P K I  G
Sbjct: 326 KTTPKEPTEKKMARAKTVMNSKTHPPKCIQCG 357



 Score = 34.3 bits (77), Expect = 0.031
 Identities = 27/97 (27%), Positives = 43/97 (44%), Gaps = 6/97 (6%)

Query: 21  GGEEEKDPDAQKKEEERQEALRQQEEERKAKHARMEAEREKVR---QQIRDKYGLKKKEE 77
           G   EK+ +  +KEE+R   LR Q +E   K    E    + R   Q   D+ G +K E+
Sbjct: 228 GTRTEKEEERDEKEEKR---LRSQTKEPTPKQKLKEEPDREARAGVQADEDEDGDEKDEK 284

Query: 78  KEAEEKAALEQPCEGSLTRPKKAIPAGCGDEEEEEEE 114
           K   +   L          P+K  P    +++E+E+E
Sbjct: 285 KHRSQPKDLAAKRRPEEKEPEKVNPQISDEKDEDEKE 321



 Score = 31.6 bits (70), Expect = 0.20
 Identities = 21/105 (20%), Positives = 52/105 (49%), Gaps = 13/105 (12%)

Query: 22  GEEEKDPDAQKKEEERQEALRQQEEERKAKHARMEAEREKVRQQI------RDKYGLKKK 75
           G  ++ P  + +  +  E+++++++++  K  R+ + RE+V + +      R K G + +
Sbjct: 174 GPAKRKPQEESERAKSDESIKEEDKDQDEKRRRVTS-RERVARPLPAEEPERAKSGTRTE 232

Query: 76  EEKEAEEKAALEQPCEGSLTRPKKAI------PAGCGDEEEEEEE 114
           +E+E +EK       +     PK+ +       A  G + +E+E+
Sbjct: 233 KEEERDEKEEKRLRSQTKEPTPKQKLKEEPDREARAGVQADEDED 277


>gi|148806928 hypothetical protein LOC57482 [Homo sapiens]
          Length = 1233

 Score = 42.4 bits (98), Expect = 1e-04
 Identities = 32/100 (32%), Positives = 50/100 (50%), Gaps = 15/100 (15%)

Query: 29  DAQKKEEERQEALRQQEEERKAK-------------HARMEAEREKVRQQIRDKYGLKKK 75
           DA+++E E +E L  +EE R+ +              AR+E  R +  ++ R    LK++
Sbjct: 302 DAERREREERERLEAEEERRRLQAQAQAEERRRLEEDARLEERRRQEEEEGRCAEELKRQ 361

Query: 76  EEKEAEEKAALEQPCEGSLTRPKKAI-PAGCGDEEEEEEE 114
           EE+EAE    LEQ  E  +  P +A+   G G    EEE+
Sbjct: 362 EEEEAEGWEELEQQ-EAEVQGPPEALEETGEGRRGAEEED 400



 Score = 32.0 bits (71), Expect = 0.15
 Identities = 28/104 (26%), Positives = 50/104 (48%), Gaps = 25/104 (24%)

Query: 22  GEEEKDP----DAQKKEEER-------QEALRQQEEERKAKHARMEAEREKVRQQIRDKY 70
           GE ++ P     A ++E++R       ++A R++ EER+    R+EAE E+ R Q     
Sbjct: 274 GEGQEPPLEAERAPREEQQRSLEAPGWEDAERREREERE----RLEAEEERRRLQA---- 325

Query: 71  GLKKKEEKEAEEKAALEQPCEGSLTRPKKAIPAGCGDEEEEEEE 114
                 + +AEE+  LE+       R ++     C +E + +EE
Sbjct: 326 ------QAQAEERRRLEEDARLEERRRQEEEEGRCAEELKRQEE 363



 Score = 28.9 bits (63), Expect = 1.3
 Identities = 23/70 (32%), Positives = 36/70 (51%), Gaps = 2/70 (2%)

Query: 23  EEEKDPDAQKKEEERQEALRQQEEERKAKHARMEAEREKVRQQIRDKYGLKKKEEKEAEE 82
           EEE +P   ++E  RQE    +E E K K  + EA  EK R + +    L+++  +E   
Sbjct: 209 EEEPNPLDSEEERRRQEDY-WRELEAKCKRQKAEA-AEKRRLEEQRLQALERRLWEENRR 266

Query: 83  KAALEQPCEG 92
           +  LE+  EG
Sbjct: 267 QELLEEEGEG 276


>gi|155030232 proline, glutamic acid and leucine rich protein 1
           [Homo sapiens]
          Length = 1130

 Score = 42.0 bits (97), Expect = 1e-04
 Identities = 17/61 (27%), Positives = 38/61 (62%)

Query: 23  EEEKDPDAQKKEEERQEALRQQEEERKAKHARMEAEREKVRQQIRDKYGLKKKEEKEAEE 82
           EEE++ + +++EEE +E   ++EE+ +      E E E+  ++  ++ G  ++EE+E +E
Sbjct: 892 EEEEEEEEEEEEEEEEEDFEEEEEDEEEYFEEEEEEEEEFEEEFEEEEGELEEEEEEEDE 951

Query: 83  K 83
           +
Sbjct: 952 E 952



 Score = 37.7 bits (86), Expect = 0.003
 Identities = 19/65 (29%), Positives = 38/65 (58%), Gaps = 3/65 (4%)

Query: 23  EEEKDPDAQKKEEERQEALRQQEEERKAKHARMEAEREKVRQQIRDKYGLKKKEEKEAEE 82
           EEE++ D +++EE+ +E   ++EEE +      E E  ++ ++  ++    ++EE+E EE
Sbjct: 903 EEEEEEDFEEEEEDEEEYFEEEEEEEEEFEEEFEEEEGELEEEEEEE---DEEEEEELEE 959

Query: 83  KAALE 87
              LE
Sbjct: 960 VEDLE 964



 Score = 37.0 bits (84), Expect = 0.005
 Identities = 27/92 (29%), Positives = 46/92 (50%), Gaps = 15/92 (16%)

Query: 29  DAQKKEEERQEALRQQEEERKAKHARMEAEREKVRQQIRDKYGLKKKEEKEAEEKAALEQ 88
           ++  +EEE +E   ++EEE + +    E E E   +   +    +++EE+E EE+   E 
Sbjct: 884 NSSDEEEEEEEEEEEEEEEEEEEEEDFEEEEEDEEEYFEE----EEEEEEEFEEEFEEE- 938

Query: 89  PCEGSLTRPKKAIPAGCGDEEEEEEESILDTV 120
             EG L   +        +EE+EEEE  L+ V
Sbjct: 939 --EGELEEEE--------EEEDEEEEEELEEV 960



 Score = 31.2 bits (69), Expect = 0.26
 Identities = 19/66 (28%), Positives = 35/66 (53%), Gaps = 7/66 (10%)

Query: 23  EEEKDPDAQKKEEERQEALRQQEEERKAKHARMEAEREKVRQQIRDKYGLKKKEEKEAEE 82
           EEE++ +   +EEE  E    +EEE + +    E E E+   +       +++EE++ EE
Sbjct: 901 EEEEEEEEDFEEEEEDEEEYFEEEEEEEEEFEEEFEEEEGELE-------EEEEEEDEEE 953

Query: 83  KAALEQ 88
           +  LE+
Sbjct: 954 EEELEE 959


>gi|18426913 drebrin 1 isoform b [Homo sapiens]
          Length = 651

 Score = 42.0 bits (97), Expect = 1e-04
 Identities = 23/86 (26%), Positives = 48/86 (55%), Gaps = 3/86 (3%)

Query: 33  KEEERQEALRQQEEERKAKHARMEAEREKV---RQQIRDKYGLKKKEEKEAEEKAALEQP 89
           ++ +++E LR++EE +KA   R+  E+E++   RQ+  ++    ++ E++ EE    +Q 
Sbjct: 184 EQAKKEEELRKEEERKKALDERLRFEQERMEQERQEQEERERRYREREQQIEEHRRKQQT 243

Query: 90  CEGSLTRPKKAIPAGCGDEEEEEEES 115
            E    + +    +  GD  +EEEE+
Sbjct: 244 LEAEEAKRRLKEQSIFGDHRDEEEET 269



 Score = 37.4 bits (85), Expect = 0.004
 Identities = 22/73 (30%), Positives = 40/73 (54%), Gaps = 3/73 (4%)

Query: 14  KDMGKMLGGEEEKDPDAQKKEEERQEALRQQE---EERKAKHARMEAEREKVRQQIRDKY 70
           K + + L  E+E+    ++++EER+   R++E   EE + K   +EAE  K R + +  +
Sbjct: 200 KALDERLRFEQERMEQERQEQEERERRYREREQQIEEHRRKQQTLEAEEAKRRLKEQSIF 259

Query: 71  GLKKKEEKEAEEK 83
           G  + EE+E   K
Sbjct: 260 GDHRDEEEETHMK 272


>gi|18426915 drebrin 1 isoform a [Homo sapiens]
          Length = 649

 Score = 42.0 bits (97), Expect = 1e-04
 Identities = 23/86 (26%), Positives = 48/86 (55%), Gaps = 3/86 (3%)

Query: 33  KEEERQEALRQQEEERKAKHARMEAEREKV---RQQIRDKYGLKKKEEKEAEEKAALEQP 89
           ++ +++E LR++EE +KA   R+  E+E++   RQ+  ++    ++ E++ EE    +Q 
Sbjct: 182 EQAKKEEELRKEEERKKALDERLRFEQERMEQERQEQEERERRYREREQQIEEHRRKQQT 241

Query: 90  CEGSLTRPKKAIPAGCGDEEEEEEES 115
            E    + +    +  GD  +EEEE+
Sbjct: 242 LEAEEAKRRLKEQSIFGDHRDEEEET 267



 Score = 37.4 bits (85), Expect = 0.004
 Identities = 22/73 (30%), Positives = 40/73 (54%), Gaps = 3/73 (4%)

Query: 14  KDMGKMLGGEEEKDPDAQKKEEERQEALRQQE---EERKAKHARMEAEREKVRQQIRDKY 70
           K + + L  E+E+    ++++EER+   R++E   EE + K   +EAE  K R + +  +
Sbjct: 198 KALDERLRFEQERMEQERQEQEERERRYREREQQIEEHRRKQQTLEAEEAKRRLKEQSIF 257

Query: 71  GLKKKEEKEAEEK 83
           G  + EE+E   K
Sbjct: 258 GDHRDEEEETHMK 270


>gi|239749449 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 275

 Score = 41.6 bits (96), Expect = 2e-04
 Identities = 16/64 (25%), Positives = 42/64 (65%)

Query: 25 EKDPDAQKKEEERQEALRQQEEERKAKHARMEAEREKVRQQIRDKYGLKKKEEKEAEEKA 84
          +++ + +K+  ER++  R++E+ERK +  + E ++ K R++ +++   +K+ EK+ +E+ 
Sbjct: 31 QRESERKKERREREKRKREREKERKRERGKKEKKKRKKRERGKERERKRKEREKQRKERR 90

Query: 85 ALEQ 88
            E+
Sbjct: 91 EKER 94



 Score = 40.8 bits (94), Expect = 3e-04
 Identities = 25/71 (35%), Positives = 39/71 (54%), Gaps = 1/71 (1%)

Query: 14  KDMGKMLGGEEEKDPDAQKKEEERQEALRQQEEERKAKHARMEAERE-KVRQQIRDKYGL 72
           K+  K      EK+   +KKE++++E  ++   ERK K  R E ERE K R++ + K   
Sbjct: 80  KEREKQRKERREKERRKRKKEKKKRERKQRGRRERKKKKERKERERENKQRRERKRKKRR 139

Query: 73  KKKEEKEAEEK 83
           KKK  KE + +
Sbjct: 140 KKKRRKERKRE 150



 Score = 40.4 bits (93), Expect = 4e-04
 Identities = 21/61 (34%), Positives = 38/61 (62%), Gaps = 3/61 (4%)

Query: 23  EEEKDPDAQKKEEERQEALRQQEEERKAKHARMEAEREKVRQQIRDKYGLKKKEEKEAEE 82
           E EK+   +K+E  ++E  ++++ ER  +  R   EREK R++ R+K   K+K+EK+  E
Sbjct: 49  EREKE---RKRERGKKEKKKRKKRERGKERERKRKEREKQRKERREKERRKRKKEKKKRE 105

Query: 83  K 83
           +
Sbjct: 106 R 106



 Score = 39.7 bits (91), Expect = 7e-04
 Identities = 23/75 (30%), Positives = 43/75 (57%), Gaps = 2/75 (2%)

Query: 14  KDMGKMLGGEEEKDPDAQKKEEERQEALRQQEEERKAKHARMEAEREKVRQQIRDKYGLK 73
           K+  K    E  K+ + ++KE E+Q   R+++E RK K  + + ER++  ++ R K   K
Sbjct: 61  KEKKKRKKRERGKERERKRKEREKQRKERREKERRKRKKEKKKRERKQRGRRERKK--KK 118

Query: 74  KKEEKEAEEKAALEQ 88
           +++E+E E K   E+
Sbjct: 119 ERKERERENKQRRER 133



 Score = 38.5 bits (88), Expect = 0.002
 Identities = 21/64 (32%), Positives = 36/64 (56%), Gaps = 2/64 (3%)

Query: 22  GEEEKDPDAQKKEEERQEALRQQEE--ERKAKHARMEAEREKVRQQIRDKYGLKKKEEKE 79
           G  E+    ++KE ER+   R++ +  +R+ K  R E +REK R +   K   +KKEE+E
Sbjct: 110 GRRERKKKKERKERERENKQRRERKRKKRRKKKRRKERKREKERGKRERKRKKRKKEERE 169

Query: 80  AEEK 83
            + +
Sbjct: 170 KKRE 173



 Score = 38.1 bits (87), Expect = 0.002
 Identities = 22/79 (27%), Positives = 44/79 (55%), Gaps = 2/79 (2%)

Query: 23  EEEKDPDAQKKEEERQEALRQQEEERKAKHARMEAEREKVRQQIRDKYGLKKKEE--KEA 80
           E E     ++K ++R++  R++E +R+ +  + E +R+K +++ R+K   + ++E  KE 
Sbjct: 124 ERENKQRRERKRKKRRKKKRRKERKREKERGKRERKRKKRKKEEREKKRERNRKERKKER 183

Query: 81  EEKAALEQPCEGSLTRPKK 99
           E K   E+  E    R KK
Sbjct: 184 ERKERRERKKERKKERRKK 202



 Score = 37.7 bits (86), Expect = 0.003
 Identities = 16/61 (26%), Positives = 38/61 (62%)

Query: 23  EEEKDPDAQKKEEERQEALRQQEEERKAKHARMEAEREKVRQQIRDKYGLKKKEEKEAEE 82
           +E K    + K E +++  +++E E+K +  R E ++E+ R++ R++   +KKE ++ +E
Sbjct: 145 KERKREKERGKRERKRKKRKKEEREKKRERNRKERKKERERKERRERKKERKKERRKKKE 204

Query: 83  K 83
           +
Sbjct: 205 R 205



 Score = 37.0 bits (84), Expect = 0.005
 Identities = 18/57 (31%), Positives = 33/57 (57%)

Query: 22  GEEEKDPDAQKKEEERQEALRQQEEERKAKHARMEAEREKVRQQIRDKYGLKKKEEK 78
           G+ E+    +KKEE  ++  R ++E +K +  +   ER+K R++ R K   +KK+ K
Sbjct: 154 GKRERKRKKRKKEEREKKRERNRKERKKERERKERRERKKERKKERRKKKERKKDRK 210



 Score = 34.7 bits (78), Expect = 0.024
 Identities = 23/91 (25%), Positives = 46/91 (50%), Gaps = 5/91 (5%)

Query: 14  KDMGKMLGGEEEKDPDAQKKEEERQEALRQQEEERKAKHARMEAEREK-----VRQQIRD 68
           K+  +  G +E+K    +++ +ER+   +++E++RK +  +   +R+K      R+Q   
Sbjct: 52  KERKRERGKKEKKKRKKRERGKERERKRKEREKQRKERREKERRKRKKEKKKRERKQRGR 111

Query: 69  KYGLKKKEEKEAEEKAALEQPCEGSLTRPKK 99
           +   KKKE KE E +    +  +    R KK
Sbjct: 112 RERKKKKERKERERENKQRRERKRKKRRKKK 142



 Score = 32.7 bits (73), Expect = 0.089
 Identities = 20/61 (32%), Positives = 35/61 (57%), Gaps = 1/61 (1%)

Query: 23  EEEKDPDAQKKEEERQEALRQQEEERKAKHARMEAEREKVRQQIRDKYGLKKKEEKEAEE 82
           E++K    Q+   ER++   ++E ER+ K  R E +R+K R++ R K   ++KE  + E 
Sbjct: 100 EKKKRERKQRGRRERKKKKERKERERENKQ-RRERKRKKRRKKKRRKERKREKERGKRER 158

Query: 83  K 83
           K
Sbjct: 159 K 159



 Score = 29.6 bits (65), Expect = 0.76
 Identities = 18/45 (40%), Positives = 30/45 (66%), Gaps = 2/45 (4%)

Query: 23  EEEKDPDAQKKEEERQEALRQQEEERKAKHARMEAEREKVRQQIR 67
           + E++   +KKE ER+E  R++++ERK K  R + ER+K R+  R
Sbjct: 171 KRERNRKERKKERERKER-RERKKERK-KERRKKKERKKDRKTDR 213


>gi|40254924 leucine rich repeat containing 59 [Homo sapiens]
          Length = 307

 Score = 41.6 bits (96), Expect = 2e-04
 Identities = 28/104 (26%), Positives = 56/104 (53%), Gaps = 7/104 (6%)

Query: 6   KQALGGATKDMGKMLGGEEEKDPDAQKKEEERQEALRQQEEERKAKHA-------RMEAE 58
           KQ    A K +  M   + +++ + Q++ E  +EA +++E +++AK A       R +AE
Sbjct: 135 KQCKQCANKVLQHMKAVQADQERERQRRLEVEREAEKKREAKQRAKEAQERELRKREKAE 194

Query: 59  REKVRQQIRDKYGLKKKEEKEAEEKAALEQPCEGSLTRPKKAIP 102
            ++ R++  D     K+E+++  +K A + P   S +RP+K  P
Sbjct: 195 EKERRRKEYDALKAAKREQEKKPKKEANQAPKSKSGSRPRKPPP 238


>gi|190684694 ubiquitin specific peptidase 8 [Homo sapiens]
          Length = 1118

 Score = 41.6 bits (96), Expect = 2e-04
 Identities = 18/53 (33%), Positives = 38/53 (71%)

Query: 31  QKKEEERQEALRQQEEERKAKHARMEAEREKVRQQIRDKYGLKKKEEKEAEEK 83
           ++++EE++E LR++E+E+KAK  +   E E   +Q + K  ++KKE ++A+++
Sbjct: 484 ERQQEEQKEKLRKEEQEQKAKKKQEAEENEITEKQQKAKEEMEKKESEQAKKE 536



 Score = 33.5 bits (75), Expect = 0.052
 Identities = 17/65 (26%), Positives = 36/65 (55%), Gaps = 3/65 (4%)

Query: 23  EEEKDPDAQKKEEERQEALRQQEEERKAKHARMEAEREKVRQQIRDKYGLKKKEEKEAEE 82
           ++E+  +  +KEE+ Q+A ++QE E      + +  +E++ ++  ++    KKE+KE   
Sbjct: 486 QQEEQKEKLRKEEQEQKAKKKQEAEENEITEKQQKAKEEMEKKESEQ---AKKEDKETSA 542

Query: 83  KAALE 87
           K   E
Sbjct: 543 KRGKE 547



 Score = 32.0 bits (71), Expect = 0.15
 Identities = 14/51 (27%), Positives = 32/51 (62%)

Query: 32  KKEEERQEALRQQEEERKAKHARMEAEREKVRQQIRDKYGLKKKEEKEAEE 82
           +K ++ +E   +Q+EE+K K  + E E++  ++Q  ++  + +K++K  EE
Sbjct: 474 EKNKQEKELRERQQEEQKEKLRKEEQEQKAKKKQEAEENEITEKQQKAKEE 524



 Score = 30.8 bits (68), Expect = 0.34
 Identities = 17/70 (24%), Positives = 43/70 (61%), Gaps = 8/70 (11%)

Query: 23  EEEKDPDAQKKEE-------ERQEALRQQEEERKAKHARMEAEREKVRQQIRDKYGLKKK 75
           +EE++  A+KK+E       E+Q+  +++ E+++++ A+ E ++E   ++ ++  G+K++
Sbjct: 496 KEEQEQKAKKKQEAEENEITEKQQKAKEEMEKKESEQAKKE-DKETSAKRGKEITGVKRQ 554

Query: 76  EEKEAEEKAA 85
            + E E   A
Sbjct: 555 SKSEHETSDA 564



 Score = 30.0 bits (66), Expect = 0.58
 Identities = 16/73 (21%), Positives = 39/73 (53%), Gaps = 3/73 (4%)

Query: 27  DPDAQKKEEERQEALRQQEEERKAKHARMEAEREKVRQQIRDKYGLKKKEEKEAEEKAAL 86
           D +  +   E    + + ++E++ +  + E ++EK+R++ +++   K K+++EAEE    
Sbjct: 459 DEEKARIHAETALLMEKNKQEKELRERQQEEQKEKLRKEEQEQ---KAKKKQEAEENEIT 515

Query: 87  EQPCEGSLTRPKK 99
           E+  +      KK
Sbjct: 516 EKQQKAKEEMEKK 528



 Score = 28.1 bits (61), Expect = 2.2
 Identities = 25/93 (26%), Positives = 44/93 (47%), Gaps = 9/93 (9%)

Query: 28  PDAQKKEEERQEALRQQEEERKAKHAR--MEAEREKVRQQIRDKYGLKKKE---EKEAEE 82
           PD   K       L   +EE+   HA   +  E+ K  +++R++   ++KE   ++E E+
Sbjct: 442 PDRSTKPVVFSPTLMLTDEEKARIHAETALLMEKNKQEKELRERQQEEQKEKLRKEEQEQ 501

Query: 83  KAALEQPCEGSLTRPKKAIPAGCGDEEEEEEES 115
           KA  +Q  E +    K+        EE E++ES
Sbjct: 502 KAKKKQEAEENEITEKQQ----KAKEEMEKKES 530



 Score = 26.2 bits (56), Expect = 8.4
 Identities = 15/66 (22%), Positives = 33/66 (50%), Gaps = 2/66 (3%)

Query: 24  EEKDPDAQKKEEERQEALRQQEEERKAKHARMEAEREKVRQQIRDKYGLKKKEEKEAEEK 83
           E+K+ +  KKE++   A R +E     + ++ E E    ++ + D+   K+    E ++K
Sbjct: 526 EKKESEQAKKEDKETSAKRGKEITGVKRQSKSEHETSDAKKSVEDRG--KRCPTPEIQKK 583

Query: 84  AALEQP 89
           +  + P
Sbjct: 584 STGDVP 589


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.305    0.127    0.339 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 6,067,777
Number of Sequences: 37866
Number of extensions: 344086
Number of successful extensions: 14960
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 857
Number of HSP's successfully gapped in prelim test: 691
Number of HSP's that attempted gapping in prelim test: 3425
Number of HSP's gapped (non-prelim): 7043
length of query: 134
length of database: 18,247,518
effective HSP length: 91
effective length of query: 43
effective length of database: 14,801,712
effective search space: 636473616
effective search space used: 636473616
T: 11
A: 40
X1: 16 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 43 (21.9 bits)
S2: 56 (26.2 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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