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Search of human proteins with 56676330
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|56676330 HP1-BP74 [Homo sapiens]
(553 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|56676330 HP1-BP74 [Homo sapiens] 1090 0.0
gi|24475863 H1 histone family, member O, oocyte-specific [Homo s... 66 7e-11
gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens] 64 5e-10
gi|153945728 microtubule-associated protein 1B [Homo sapiens] 58 2e-08
gi|4885371 H1 histone family, member 0 [Homo sapiens] 54 3e-07
gi|104526627 triadin [Homo sapiens] 54 3e-07
gi|17975763 myelin transcription factor 1 [Homo sapiens] 54 4e-07
gi|157738649 neurofilament, medium polypeptide 150kDa isoform 1 ... 52 1e-06
gi|157738641 neurofilament, medium polypeptide 150kDa isoform 2 ... 52 1e-06
gi|148763345 cell division cycle 2-like 2 isoform 4 [Homo sapiens] 50 5e-06
gi|148763347 cell division cycle 2-like 2 isoform 1 [Homo sapiens] 50 5e-06
gi|16332372 cell division cycle 2-like 1 (PITSLRE proteins) isof... 50 5e-06
gi|16332370 cell division cycle 2-like 1 (PITSLRE proteins) isof... 50 5e-06
gi|16332364 cell division cycle 2-like 1 (PITSLRE proteins) isof... 50 5e-06
gi|16332362 cell division cycle 2-like 1 (PITSLRE proteins) isof... 50 5e-06
gi|16332358 cell division cycle 2-like 1 (PITSLRE proteins) isof... 50 5e-06
gi|20544168 histone cluster 1, H1t [Homo sapiens] 50 5e-06
gi|10835063 nucleophosmin 1 isoform 1 [Homo sapiens] 49 9e-06
gi|4885379 histone cluster 1, H1e [Homo sapiens] 49 9e-06
gi|4885375 histone cluster 1, H1c [Homo sapiens] 49 9e-06
gi|4885377 histone cluster 1, H1d [Homo sapiens] 49 1e-05
gi|4885381 histone cluster 1, H1b [Homo sapiens] 49 1e-05
gi|55956788 nucleolin [Homo sapiens] 49 2e-05
gi|197927454 DEK oncogene isoform 2 [Homo sapiens] 49 2e-05
gi|4503249 DEK oncogene isoform 1 [Homo sapiens] 49 2e-05
gi|94536805 splicing factor YT521-B isoform 2 [Homo sapiens] 48 2e-05
gi|72534750 splicing factor YT521-B isoform 1 [Homo sapiens] 48 2e-05
gi|83641870 nucleophosmin 1 isoform 3 [Homo sapiens] 48 3e-05
gi|39780597 PNMA-like 1 isoform a [Homo sapiens] 48 3e-05
gi|21361272 myeloid/lymphoid or mixed-lineage leukemia (trithora... 47 3e-05
>gi|56676330 HP1-BP74 [Homo sapiens]
Length = 553
Score = 1090 bits (2819), Expect = 0.0
Identities = 553/553 (100%), Positives = 553/553 (100%)
Query: 1 MATDTSQGELVHPKALPLIVGAQLIHADKLGEKVEDSTMPIRRTVNSTRETPPKSKLAEG 60
MATDTSQGELVHPKALPLIVGAQLIHADKLGEKVEDSTMPIRRTVNSTRETPPKSKLAEG
Sbjct: 1 MATDTSQGELVHPKALPLIVGAQLIHADKLGEKVEDSTMPIRRTVNSTRETPPKSKLAEG 60
Query: 61 EEEKPEPDISSEESVSTVEEQENETPPATSSEAEQPKGEPENEEKEENKSSEETKKDEKD 120
EEEKPEPDISSEESVSTVEEQENETPPATSSEAEQPKGEPENEEKEENKSSEETKKDEKD
Sbjct: 61 EEEKPEPDISSEESVSTVEEQENETPPATSSEAEQPKGEPENEEKEENKSSEETKKDEKD 120
Query: 121 QSKEKEKKVKKTIPSWATLSASQLARAQKQTPMASSPRPKMDAILTEAIKACFQKSGASV 180
QSKEKEKKVKKTIPSWATLSASQLARAQKQTPMASSPRPKMDAILTEAIKACFQKSGASV
Sbjct: 121 QSKEKEKKVKKTIPSWATLSASQLARAQKQTPMASSPRPKMDAILTEAIKACFQKSGASV 180
Query: 181 VAIRKYIIHKYPSLELERRGYLLKQALKRELNRGVIKQVKGKGASGSFVVVQKSRKTPQK 240
VAIRKYIIHKYPSLELERRGYLLKQALKRELNRGVIKQVKGKGASGSFVVVQKSRKTPQK
Sbjct: 181 VAIRKYIIHKYPSLELERRGYLLKQALKRELNRGVIKQVKGKGASGSFVVVQKSRKTPQK 240
Query: 241 SRNRKNRSSAVDPEPQVKLEDVLPLAFTRLCEPKEASYSLIRKYVSQYYPKLRVDIRPQL 300
SRNRKNRSSAVDPEPQVKLEDVLPLAFTRLCEPKEASYSLIRKYVSQYYPKLRVDIRPQL
Sbjct: 241 SRNRKNRSSAVDPEPQVKLEDVLPLAFTRLCEPKEASYSLIRKYVSQYYPKLRVDIRPQL 300
Query: 301 LKNALQRAVERGQLEQITGKGASGTFQLKKSGEKPLLGGSLMEYAILSAIAAMNEPKTCS 360
LKNALQRAVERGQLEQITGKGASGTFQLKKSGEKPLLGGSLMEYAILSAIAAMNEPKTCS
Sbjct: 301 LKNALQRAVERGQLEQITGKGASGTFQLKKSGEKPLLGGSLMEYAILSAIAAMNEPKTCS 360
Query: 361 TTALKKYVLENHPGTNSNYQMHLLKKTLQKCEKNGWMEQISGKGFSGTFQLCFPYYPSPG 420
TTALKKYVLENHPGTNSNYQMHLLKKTLQKCEKNGWMEQISGKGFSGTFQLCFPYYPSPG
Sbjct: 361 TTALKKYVLENHPGTNSNYQMHLLKKTLQKCEKNGWMEQISGKGFSGTFQLCFPYYPSPG 420
Query: 421 VLFPKKEPDDSRDEDEDEDESSEEDSEDEEPPPKRRLQKKTPAKSPGKAASVKQRGSKPA 480
VLFPKKEPDDSRDEDEDEDESSEEDSEDEEPPPKRRLQKKTPAKSPGKAASVKQRGSKPA
Sbjct: 421 VLFPKKEPDDSRDEDEDEDESSEEDSEDEEPPPKRRLQKKTPAKSPGKAASVKQRGSKPA 480
Query: 481 PKVSAAQRGKARPLPKKAPPKAKTPAKKTRPSSTVIKKPSGGSSKKPATSARKEVKLPGK 540
PKVSAAQRGKARPLPKKAPPKAKTPAKKTRPSSTVIKKPSGGSSKKPATSARKEVKLPGK
Sbjct: 481 PKVSAAQRGKARPLPKKAPPKAKTPAKKTRPSSTVIKKPSGGSSKKPATSARKEVKLPGK 540
Query: 541 GKSTMKKSFRVKK 553
GKSTMKKSFRVKK
Sbjct: 541 GKSTMKKSFRVKK 553
>gi|24475863 H1 histone family, member O, oocyte-specific [Homo
sapiens]
Length = 346
Score = 66.2 bits (160), Expect = 7e-11
Identities = 36/84 (42%), Positives = 56/84 (66%), Gaps = 3/84 (3%)
Query: 159 PKMDAILTEAIKACFQKSGASVVAIRKYIIHKYPSLELERRGYLLKQALKRELNRGVIKQ 218
P + ++ EA++A Q+ G SV AI+ YI+HKYP++++ R YLLKQAL + RG++ +
Sbjct: 53 PPVLRMVLEALQAGEQRRGTSVAAIKLYILHKYPTVDVLRFKYLLKQALATGMRRGLLAR 112
Query: 219 ---VKGKGASGSFVVVQKSRKTPQ 239
K +GA+GSF +V K +K Q
Sbjct: 113 PLNSKARGATGSFKLVPKHKKKIQ 136
Score = 56.2 bits (134), Expect = 8e-08
Identities = 59/216 (27%), Positives = 91/216 (42%), Gaps = 19/216 (8%)
Query: 346 ILSAIAAMNEPKTCSTTALKKYVLENHPGTNSNYQMHLLKKTLQKCEKNGWMEQ---ISG 402
+L A+ A + + S A+K Y+L +P + +LLK+ L + G + +
Sbjct: 59 VLEALQAGEQRRGTSVAAIKLYILHKYPTVDVLRFKYLLKQALATGMRRGLLARPLNSKA 118
Query: 403 KGFSGTFQLCFPYYP--SPGVLFPKKEPDDSRDEDEDEDESSEEDSEDEEPPP------- 453
+G +G+F+L + P + P P R E + + ++ SE +E PP
Sbjct: 119 RGATGSFKLVPKHKKKIQPRKMAPATAP---RRAGEAKGKGPKKPSEAKEDPPNVGKVKK 175
Query: 454 --KRRLQKKTPAKSPGKAASVKQRGSKPAPKVSAAQRGKARPLPKKAPPKAKTPAKKTRP 511
KR + + P PG AA+ K R A K + AQ G+AR +P K P KA
Sbjct: 176 AAKRPAKVQKPPPKPG-AATEKARKQGGAAKDTRAQSGEARKVPPK-PDKAMRAPSSAGG 233
Query: 512 SSTVIKKPSGGSSKKPATSARKEVKLPGKGKSTMKK 547
S K SS+ A + RK K T K
Sbjct: 234 LSRKAKAKGSRSSQGDAEAYRKTKAESKSSKPTASK 269
Score = 39.7 bits (91), Expect = 0.007
Identities = 35/146 (23%), Positives = 53/146 (36%), Gaps = 24/146 (16%)
Query: 417 PSPGVLFPKKEPDDSRDEDEDEDESSEEDSEDEEPPPKRRLQKKTPAKSPGKAASVKQRG 476
P PG K +R + ++ + E + PPK + P+ + G + K +G
Sbjct: 188 PKPGAATEK-----ARKQGGAAKDTRAQSGEARKVPPKPDKAMRAPSSAGGLSRKAKAKG 242
Query: 477 SKPA------------------PKVSAAQRGKARPLPKKAPPKAKTPAKKTRPSSTVIKK 518
S+ + P S + G A P KK KAK P P++
Sbjct: 243 SRSSQGDAEAYRKTKAESKSSKPTASKVKNGAASPTKKKVVAKAKAPKAGQGPNTKAAAP 302
Query: 519 PSGGSSK-KPATSARKEVKLPGKGKS 543
G SK PA +RK G K+
Sbjct: 303 AKGSGSKVVPAHLSRKTEAPKGPRKA 328
>gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens]
Length = 1020
Score = 63.5 bits (153), Expect = 5e-10
Identities = 117/520 (22%), Positives = 195/520 (37%), Gaps = 97/520 (18%)
Query: 50 ETPPKSKLAEGEEEKPEPDISSEESVSTVEEQENETPPATSS----------EAEQPKGE 99
++PP++K E EE K ++ S E + ++E ++P S EA+ P E
Sbjct: 559 KSPPEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPAEAKSPEKAKSPVKEEAKSP-AE 617
Query: 100 PENEEKEENKSSEETKKDEKDQSKEKEKKVKKTIPSWATLSASQLARAQKQTPMASSPRP 159
++ KEE KS E K EK +S KE+ S + +K+ A SP
Sbjct: 618 AKSPVKEEAKSPAEVKSPEKAKSPTKEE----------AKSPEKAKSPEKEE--AKSPEK 665
Query: 160 KMDAILTEAIKACFQKSGASVVAIRKYIIHKYPSLELERRGYLLKQALKRELNRGVIKQV 219
+ EA KS A K P + + + ++A E + +K+
Sbjct: 666 AKSPVKAEAKSPEKAKSPVKAEA-------KSPE---KAKSPVKEEAKSPEKAKSPVKE- 714
Query: 220 KGKGASGSFVVVQKSRKTPQKSRN-----RKNRSSAVDPEPQVKLEDVLPLAFTRLCEPK 274
+ K + V++ KTP+K+++ K+ A PE L+ P A T K
Sbjct: 715 EAKSPEKAKSPVKEEAKTPEKAKSPVKEEAKSPEKAKSPEKAKTLDVKSPEAKT---PAK 771
Query: 275 EASYSLIRKYVSQYYPKLRVDIR-PQLLKNALQRAVERGQLEQITGKGASGTFQLKKSGE 333
E + S K+ + ++ +++ P+ K+ L+ + + E + K E
Sbjct: 772 EEARSPADKFPEKAKSPVKEEVKSPEKAKSPLKEDAKAPEKEIPKKEEVKSPV---KEEE 828
Query: 334 KPLLGGSLMEYAILSAIAAMNEPKTCSTTALKKYVLENHPGTNSNYQMHLLKKTLQKCEK 393
KP + EP KK E P T + KK + +K
Sbjct: 829 KP-------------QEVKVKEPP-------KKAEEEKAPATPKTEEKKDSKKE-EAPKK 867
Query: 394 NGWMEQISGKGFSGTFQLCFPYYPSPGVLFPKKEPDDSRDED----------EDEDESSE 443
++ K P V PK+ +++ E+ E E +
Sbjct: 868 EAPKPKVEEK-------------KEPAVEKPKESKVEAKKEEAEDKKKVPTPEKEAPAKV 914
Query: 444 EDSEDEEPPPKRRLQKKTPAKSPGKAASVKQRGSKPAPKVSAAQRGKARPLPKKAPPKAK 503
E ED +P K + KK P + K S + AP+ + KA KK K K
Sbjct: 915 EVKEDAKPKEKTEVAKKEPDDAKAKEPSKPAEKKEAAPEKKDTKEEKA----KKPEEKPK 970
Query: 504 TPAKKTRPSSTVIK---KPSGGSSKKPATSARKEVKLPGK 540
T AK T+ K KP ++K +++ +K+ K P K
Sbjct: 971 TEAKAKEDDKTLSKEPSKPKAEKAEKSSSTDQKDSKPPEK 1010
Score = 62.0 bits (149), Expect = 1e-09
Identities = 40/122 (32%), Positives = 56/122 (45%), Gaps = 10/122 (8%)
Query: 426 KEPDDSRDEDEDEDESSEEDSEDEEPPPKRRLQKKTPAKSPGKAASVKQRGSKPAPKVSA 485
KE + +E +E+E+ + E + PP + + AKSP VK+ PA S
Sbjct: 479 KEEEGKEEEGGEEEEAEGGEEETKSPPAEEAASPEKEAKSP-----VKEEAKSPAEAKSP 533
Query: 486 AQRGKARPLPKKAPPKAKTPAKKTRPSSTVIKKPSGGSSKKPATSARKEVKLPGKGKSTM 545
+ P K+P KAK+PAK+ S K P +K PA EVK P K KS
Sbjct: 534 EKEEAKSPAEVKSPEKAKSPAKEEAKSPPEAKSPEKEEAKSPA-----EVKSPEKAKSPA 588
Query: 546 KK 547
K+
Sbjct: 589 KE 590
Score = 59.3 bits (142), Expect = 9e-09
Identities = 40/127 (31%), Positives = 58/127 (45%), Gaps = 6/127 (4%)
Query: 426 KEPDDSRDEDEDEDESSEE--DSEDEEPPPKRRLQKKTPAKSPGKAAS-VKQRGSKPAPK 482
K P +++ +++E +S E E + P K + AKSP KA S VK+ PA
Sbjct: 559 KSPPEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPAEAKSPEKAKSPVKEEAKSPAEA 618
Query: 483 VSAAQRGKARPLPKKAPPKAKTPAKKTRPSSTVIKKPSGGSSKKP---ATSARKEVKLPG 539
S + P K+P KAK+P K+ S K P +K P + + E K P
Sbjct: 619 KSPVKEEAKSPAEVKSPEKAKSPTKEEAKSPEKAKSPEKEEAKSPEKAKSPVKAEAKSPE 678
Query: 540 KGKSTMK 546
K KS +K
Sbjct: 679 KAKSPVK 685
Score = 55.5 bits (132), Expect = 1e-07
Identities = 38/127 (29%), Positives = 60/127 (47%), Gaps = 8/127 (6%)
Query: 424 PKKEPDDSRDEDEDEDESSEEDSEDEEPPPKRRLQKKTPAKSPGKAASVKQRGSKPAPKV 483
P KE S E + +++ E+ + P K + +K AKSP KA S + +K K
Sbjct: 621 PVKEEAKSPAEVKSPEKAKSPTKEEAKSPEKAKSPEKEEAKSPEKAKSPVKAEAKSPEKA 680
Query: 484 SAAQRGKARPLPKKAPPKAKTPAKKTRPSSTVIKKPSGGSSKKP---ATSARKEVKLPGK 540
+ + +A K+P KAK+P K+ S K P +K P + ++E K P K
Sbjct: 681 KSPVKAEA-----KSPEKAKSPVKEEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKTPEK 735
Query: 541 GKSTMKK 547
KS +K+
Sbjct: 736 AKSPVKE 742
Score = 55.1 bits (131), Expect = 2e-07
Identities = 121/543 (22%), Positives = 219/543 (40%), Gaps = 66/543 (12%)
Query: 35 EDSTMPIRRTVNSTRE---TPPKSKLAEGEEEKPEPDISSEESVSTVEEQENETPP-ATS 90
E++ P + + +E +P ++K E EE K ++ S E + ++E ++PP A S
Sbjct: 507 EEAASPEKEAKSPVKEEAKSPAEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPPEAKS 566
Query: 91 SEAEQPKGEPE--------NEEKEENKSSEETKKDEKDQSKEKEKK---------VKKTI 133
E E+ K E + KEE KS E K EK +S KE+ VK+
Sbjct: 567 PEKEEAKSPAEVKSPEKAKSPAKEEAKSPAEAKSPEKAKSPVKEEAKSPAEAKSPVKEEA 626
Query: 134 PSWATLSASQLARA----QKQTPMASSPRPKMDAILTEAIKACFQKSGASVVAIRKYIIH 189
S A + + + A++ + ++P + K +A E K+ + S + +
Sbjct: 627 KSPAEVKSPEKAKSPTKEEAKSPEKAKSPEKEEAKSPEKAKSPVKAEAKSPEKAKSPVKA 686
Query: 190 KYPSLELERRGYLLKQALKRELNRGVIKQVKGKGASGSFVVVQKSRKTPQKSRN-----R 244
+ S E + + + ++A E + +K+ + K + V++ KTP+K+++
Sbjct: 687 EAKSPE-KAKSPVKEEAKSPEKAKSPVKE-EAKSPEKAKSPVKEEAKTPEKAKSPVKEEA 744
Query: 245 KNRSSAVDPEPQVKLEDVLPLAFTRLCEPKEASYSLIRKYVSQYYPKLRVDIR-PQLLKN 303
K+ A PE L+ P A T KE + S K+ + ++ +++ P+ K+
Sbjct: 745 KSPEKAKSPEKAKTLDVKSPEAKT---PAKEEARSPADKFPEKAKSPVKEEVKSPEKAKS 801
Query: 304 ALQRAVERGQLEQITGKGASGTFQLKKSGEKPLLGGSLMEYAILSAIAAMNEPKTCST-- 361
L+ + + E + K EKP E + E K +T
Sbjct: 802 PLKEDAKAPEKEIPKKEEVKSPV---KEEEKP------QEVKVKEPPKKAEEEKAPATPK 852
Query: 362 TALKKYVLENHPGTNSNYQMHLLKKTLQKCEKNGWMEQISGKGFSGTFQLCFPYYPSPGV 421
T KK + + + +K EK + + K + + P+P
Sbjct: 853 TEEKKDSKKEEAPKKEAPKPKVEEKKEPAVEKPKESKVEAKKEEAEDKKKV----PTPEK 908
Query: 422 LFPKKEP--DDSRDEDEDEDESSEEDSEDEEPPPKRRLQKKTPAKSPGKAASVKQRGSKP 479
P K +D++ +++ E E D + P K +KK A P K + +++ KP
Sbjct: 909 EAPAKVEVKEDAKPKEKTEVAKKEPDDAKAKEPSKPA-EKKEAA--PEKKDTKEEKAKKP 965
Query: 480 --APKVSAAQRGKARPLPKKAPPKAKTPAKKTRPSSTVIKKPSGGSSKKPATSARKEVKL 537
PK A + + L K+ P K K A+K SS+ +K S KP A ++
Sbjct: 966 EEKPKTEAKAKEDDKTLSKE-PSKPK--AEKAEKSSSTDQKDS-----KPPEKATEDKAA 1017
Query: 538 PGK 540
GK
Sbjct: 1018 KGK 1020
Score = 55.1 bits (131), Expect = 2e-07
Identities = 39/133 (29%), Positives = 64/133 (48%), Gaps = 9/133 (6%)
Query: 424 PKKEPDDSRDEDEDEDESSEEDSEDEEPPPKRRLQKKTPAKSPGKAASVKQRGSKPAPKV 483
P+K +++E + +++ + E+ + P K + K AKSP KA S + +K K
Sbjct: 635 PEKAKSPTKEEAKSPEKAKSPEKEEAKSPEKAKSPVKAEAKSPEKAKSPVKAEAKSPEKA 694
Query: 484 SAAQRGKARPLPKKAPPKAKTPAKKTRPSSTVIKKPSGGSSKKP---ATSARKEVKLPGK 540
+ + +A K+P KAK+P K+ S K P +K P + ++E K P K
Sbjct: 695 KSPVKEEA-----KSPEKAKSPVKEEAKSPEKAKSPVKEEAKTPEKAKSPVKEEAKSPEK 749
Query: 541 GKSTMK-KSFRVK 552
KS K K+ VK
Sbjct: 750 AKSPEKAKTLDVK 762
Score = 54.3 bits (129), Expect = 3e-07
Identities = 39/130 (30%), Positives = 60/130 (46%), Gaps = 7/130 (5%)
Query: 424 PKKEPDDSRDEDEDEDESSEEDSEDEEPPPKRRLQKKTPAKSPGKAAS-VKQRGSKPAPK 482
P+K + E + +++ E+ + P K + K AKSP KA S VK+ P
Sbjct: 677 PEKAKSPVKAEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKTPEKA 736
Query: 483 VSAAQRGKARPLPKKAPPKAKT-----PAKKTRPSSTVIKKPSGGSSKKPATSARKEVKL 537
S + P K+P KAKT P KT P+ + P+ +K + ++EVK
Sbjct: 737 KSPVKEEAKSPEKAKSPEKAKTLDVKSPEAKT-PAKEEARSPADKFPEKAKSPVKEEVKS 795
Query: 538 PGKGKSTMKK 547
P K KS +K+
Sbjct: 796 PEKAKSPLKE 805
Score = 53.1 bits (126), Expect = 6e-07
Identities = 39/128 (30%), Positives = 62/128 (48%), Gaps = 10/128 (7%)
Query: 425 KKEPDDSRDEDEDEDES--SEEDSEDEEPPPKRRLQKKTPA--KSPGKAASVKQRGSKPA 480
K P + E E +S EE E + + K+PA KSP KA S + +K
Sbjct: 502 KSPPAEEAASPEKEAKSPVKEEAKSPAEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSP 561
Query: 481 PKVSAAQRGKAR-PLPKKAPPKAKTPAKKTRPSSTVIKKPSGGSSKKPATSARKEVKLPG 539
P+ + ++ +A+ P K+P KAK+PAK+ S K P +K + ++E K P
Sbjct: 562 PEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPAEAKSP-----EKAKSPVKEEAKSPA 616
Query: 540 KGKSTMKK 547
+ KS +K+
Sbjct: 617 EAKSPVKE 624
Score = 52.8 bits (125), Expect = 8e-07
Identities = 38/125 (30%), Positives = 59/125 (47%), Gaps = 8/125 (6%)
Query: 426 KEPDDSRDEDEDEDESSEEDSEDEEPPPKRRLQKKTP--AKSPGKAASVKQRGSKPAPKV 483
K P +++ +++E +S E E+ + + K+P AKSP K + K K
Sbjct: 525 KSPAEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPPEAKSPEKEEAKSPAEVKSPEKA 584
Query: 484 SAAQRGKAR-PLPKKAPPKAKTPAKKTRPSSTVIKKPSGGSSKKPATSARKEVKLPGKGK 542
+ + +A+ P K+P KAK+P K+ S K P +K PA EVK P K K
Sbjct: 585 KSPAKEEAKSPAEAKSPEKAKSPVKEEAKSPAEAKSPVKEEAKSPA-----EVKSPEKAK 639
Query: 543 STMKK 547
S K+
Sbjct: 640 SPTKE 644
Score = 50.8 bits (120), Expect = 3e-06
Identities = 43/124 (34%), Positives = 61/124 (49%), Gaps = 13/124 (10%)
Query: 34 VEDSTMPIRRTVNSTRETPPKSKLAEGEEEKPEPDISSEESVSTVEEQENETPPATSSEA 93
VE+ T + T T E ++K EG+EE+ EE + E+E ++PPA EA
Sbjct: 457 VEEQTEETQVTEEVTEEEEKEAKEEEGKEEE-----GGEEEEAEGGEEETKSPPA--EEA 509
Query: 94 EQPKGEPENEEKEENKSSEETKKDEKDQSKEKEKKVKKTIPSWATLSASQLARAQKQTPM 153
P+ E ++ KEE KS E K EK+++K +VK P A A + A K P
Sbjct: 510 ASPEKEAKSPVKEEAKSPAEAKSPEKEEAK-SPAEVKS--PEKAKSPAKEEA---KSPPE 563
Query: 154 ASSP 157
A SP
Sbjct: 564 AKSP 567
Score = 50.1 bits (118), Expect = 5e-06
Identities = 34/128 (26%), Positives = 59/128 (46%), Gaps = 4/128 (3%)
Query: 424 PKKEPDDSRDEDEDEDESSEEDSEDEEPPPKRRLQKKTPAKSPGKAASVKQRGSKPAPKV 483
P KE S E + +++ E+ + P + + K AKSP + S ++ S +
Sbjct: 587 PAKEEAKSPAEAKSPEKAKSPVKEEAKSPAEAKSPVKEEAKSPAEVKSPEKAKSPTKEEA 646
Query: 484 SAAQRGKARPLPK-KAPPKAKTPAKKTRPSSTVIKKPSGGSSKKP---ATSARKEVKLPG 539
+ ++ K+ + K+P KAK+P K S K P +K P + ++E K P
Sbjct: 647 KSPEKAKSPEKEEAKSPEKAKSPVKAEAKSPEKAKSPVKAEAKSPEKAKSPVKEEAKSPE 706
Query: 540 KGKSTMKK 547
K KS +K+
Sbjct: 707 KAKSPVKE 714
Score = 47.8 bits (112), Expect = 3e-05
Identities = 37/127 (29%), Positives = 58/127 (45%), Gaps = 8/127 (6%)
Query: 424 PKKEPDDSRDEDEDEDESSEEDSEDEEPPPKRRLQKKTPAKSPGKAASVKQRGSKPAPKV 483
P KE S E + + + + + P K + K AKSP KA S ++ +K K
Sbjct: 607 PVKEEAKSPAEAKSPVKEEAKSPAEVKSPEKAKSPTKEEAKSPEKAKSPEKEEAKSPEKA 666
Query: 484 SAAQRGKAR-PLPKKAPPK--AKTPAKKTRPSSTVIKKPSGGSSKKPATSARKEVKLPGK 540
+ + +A+ P K+P K AK+P K P K P +K + ++E K P K
Sbjct: 667 KSPVKAEAKSPEKAKSPVKAEAKSPEKAKSPVKEEAKSP-----EKAKSPVKEEAKSPEK 721
Query: 541 GKSTMKK 547
KS +K+
Sbjct: 722 AKSPVKE 728
Score = 47.8 bits (112), Expect = 3e-05
Identities = 42/148 (28%), Positives = 62/148 (41%), Gaps = 23/148 (15%)
Query: 426 KEPDDSRDEDEDEDESSEEDSE----DEEPPPKRRLQKKTPAKSPGKAAS-VKQRGSKPA 480
K P+ ++ +++E +S E+ + + P K + K AKSP KA S VK+ P
Sbjct: 647 KSPEKAKSPEKEEAKSPEKAKSPVKAEAKSPEKAKSPVKAEAKSPEKAKSPVKEEAKSPE 706
Query: 481 PKVSAAQRGKARPLPKKAPPK--AKTPAKKTRPSSTVIKKPSGGSSKKPA---------- 528
S + P K+P K AKTP K P K P S + A
Sbjct: 707 KAKSPVKEEAKSPEKAKSPVKEEAKTPEKAKSPVKEEAKSPEKAKSPEKAKTLDVKSPEA 766
Query: 529 -TSARKEV-----KLPGKGKSTMKKSFR 550
T A++E K P K KS +K+ +
Sbjct: 767 KTPAKEEARSPADKFPEKAKSPVKEEVK 794
Score = 47.0 bits (110), Expect = 5e-05
Identities = 41/141 (29%), Positives = 65/141 (46%), Gaps = 15/141 (10%)
Query: 27 ADKLGEKVEDSTMPIRRTVNSTRETPPKSKLAEGEEEK-PEPDISSEESV-STVEEQENE 84
ADK EK + P++ V S P K+K E+ K PE +I +E V S V+E+E
Sbjct: 778 ADKFPEKAKS---PVKEEVKS----PEKAKSPLKEDAKAPEKEIPKKEEVKSPVKEEEKP 830
Query: 85 TP-----PATSSEAEQPKGEPENEEKEENKSSEETKKDEKDQSKEKEKKVKKTIPSWATL 139
P +E E+ P+ EEK+++K E KK+ E++K+ P + +
Sbjct: 831 QEVKVKEPPKKAEEEKAPATPKTEEKKDSKKEEAPKKEAPKPKVEEKKEPAVEKPKESKV 890
Query: 140 SA-SQLARAQKQTPMASSPRP 159
A + A +K+ P P
Sbjct: 891 EAKKEEAEDKKKVPTPEKEAP 911
Score = 43.9 bits (102), Expect = 4e-04
Identities = 32/118 (27%), Positives = 57/118 (48%), Gaps = 8/118 (6%)
Query: 433 DEDEDEDESSEEDSEDEEPPPKRRLQKKTPAKSPGKAASVKQRGSKPAPKVSAAQRGKAR 492
+E +E + +EE +E+EE K K+ +A ++ P + +A+ +A+
Sbjct: 458 EEQTEETQVTEEVTEEEEKEAKEEEGKEEEGGEEEEAEGGEEETKSPPAEEAASPEKEAK 517
Query: 493 PLPK---KAPPKAKTPAKKTRPSSTVIKKPSGGSSKKPATSARKEVKLPGKGKSTMKK 547
K K+P +AK+P K+ S +K P +K PA ++E K P + KS K+
Sbjct: 518 SPVKEEAKSPAEAKSPEKEEAKSPAEVKSPE--KAKSPA---KEEAKSPPEAKSPEKE 570
Score = 43.5 bits (101), Expect = 5e-04
Identities = 39/139 (28%), Positives = 53/139 (38%), Gaps = 10/139 (7%)
Query: 418 SPGVLFPKKEPDDSRDEDEDEDESSEEDSEDEEPPPKRRLQKKTPAKSPGKAASVKQRGS 477
SP P KE S D+ +++ E+ + P K + K AK+P K K+
Sbjct: 763 SPEAKTPAKEEARS-PADKFPEKAKSPVKEEVKSPEKAKSPLKEDAKAPEKEIPKKEEVK 821
Query: 478 KPAPKVSAAQRGKARPLPK-----KAPPKAKTPAKKTRPSSTVIK----KPSGGSSKKPA 528
P + Q K + PK KAP KT KK K KP K+PA
Sbjct: 822 SPVKEEEKPQEVKVKEPPKKAEEEKAPATPKTEEKKDSKKEEAPKKEAPKPKVEEKKEPA 881
Query: 529 TSARKEVKLPGKGKSTMKK 547
KE K+ K + K
Sbjct: 882 VEKPKESKVEAKKEEAEDK 900
Score = 39.7 bits (91), Expect = 0.007
Identities = 33/141 (23%), Positives = 64/141 (45%), Gaps = 17/141 (12%)
Query: 33 KVEDSTMPIRRTVNSTRETPPKSKLAEGEEEKPEPDISSEESVSTVEEQENETPPATS-- 90
KVE+ P V +E+ ++K E E++K P +E+ + VE +E+ P +
Sbjct: 873 KVEEKKEP---AVEKPKESKVEAKKEEAEDKKKVPT-PEKEAPAKVEVKEDAKPKEKTEV 928
Query: 91 -------SEAEQPKGEPENEE----KEENKSSEETKKDEKDQSKEKEKKVKKTIPSWATL 139
++A++P E +E K++ K + K +EK +++ K K+ KT+ +
Sbjct: 929 AKKEPDDAKAKEPSKPAEKKEAAPEKKDTKEEKAKKPEEKPKTEAKAKEDDKTLSKEPSK 988
Query: 140 SASQLARAQKQTPMASSPRPK 160
++ A T S P+
Sbjct: 989 PKAEKAEKSSSTDQKDSKPPE 1009
Score = 38.9 bits (89), Expect = 0.012
Identities = 47/236 (19%), Positives = 92/236 (38%), Gaps = 30/236 (12%)
Query: 33 KVEDSTMPIRRTVNSTRETPPKSKLAEGEEEKPEPDISSEESVSTVEEQENETPPATSSE 92
K D P +T P K E + + ++ S E + +++ + P +
Sbjct: 757 KTLDVKSPEAKTPAKEEARSPADKFPEKAKSPVKEEVKSPEKAKSPLKEDAKAPEKEIPK 816
Query: 93 AEQPKGEPENEEK-EENKSSEETKKDEKDQS----KEKEKKVKKTIPSWATLSASQLARA 147
E+ K + EEK +E K E KK E++++ K +EKK K
Sbjct: 817 KEEVKSPVKEEEKPQEVKVKEPPKKAEEEKAPATPKTEEKKDSK---------------- 860
Query: 148 QKQTPMASSPRPKMDAILTEAIKACFQKSGASVVAIRKYIIH---KYPSLELE--RRGYL 202
+++ P +P+PK++ E + +K S V +K K P+ E E + +
Sbjct: 861 KEEAPKKEAPKPKVE----EKKEPAVEKPKESKVEAKKEEAEDKKKVPTPEKEAPAKVEV 916
Query: 203 LKQALKRELNRGVIKQVKGKGASGSFVVVQKSRKTPQKSRNRKNRSSAVDPEPQVK 258
+ A +E K+ A +K P+K ++ ++ + +P+ +
Sbjct: 917 KEDAKPKEKTEVAKKEPDDAKAKEPSKPAEKKEAAPEKKDTKEEKAKKPEEKPKTE 972
Score = 36.6 bits (83), Expect = 0.062
Identities = 33/138 (23%), Positives = 60/138 (43%), Gaps = 8/138 (5%)
Query: 29 KLGEKVEDSTMPIRRTVNSTRETPPKSKLAEGE-EEKPEPDISS--EESVSTVEEQENET 85
K E+ +T +S +E PK + + + EEK EP + E V +E+ +
Sbjct: 841 KAEEEKAPATPKTEEKKDSKKEEAPKKEAPKPKVEEKKEPAVEKPKESKVEAKKEEAEDK 900
Query: 86 PPATSSEAEQPKGEPENEEKEENKSSEETKKDEKDQSKEKEKKVKKTIPSWATLSASQLA 145
+ E E P + E KE+ K E+T+ +K+ K K+ K P+ +A +
Sbjct: 901 KKVPTPEKEAPA---KVEVKEDAKPKEKTEVAKKEPDDAKAKEPSK--PAEKKEAAPEKK 955
Query: 146 RAQKQTPMASSPRPKMDA 163
+++ +PK +A
Sbjct: 956 DTKEEKAKKPEEKPKTEA 973
Score = 36.6 bits (83), Expect = 0.062
Identities = 26/99 (26%), Positives = 41/99 (41%), Gaps = 1/99 (1%)
Query: 33 KVEDSTMPIRRTVNSTRETPPKSKLAEGEEEKPEPDISSEESVSTVEEQENETPPATSSE 92
K ++ T ++ + + P SK AE +E PE + EE EE+ A +
Sbjct: 921 KPKEKTEVAKKEPDDAKAKEP-SKPAEKKEAAPEKKDTKEEKAKKPEEKPKTEAKAKEDD 979
Query: 93 AEQPKGEPENEEKEENKSSEETKKDEKDQSKEKEKKVKK 131
K + + ++ KSS +KD K K E K K
Sbjct: 980 KTLSKEPSKPKAEKAEKSSSTDQKDSKPPEKATEDKAAK 1018
Score = 35.8 bits (81), Expect = 0.11
Identities = 36/114 (31%), Positives = 50/114 (43%), Gaps = 12/114 (10%)
Query: 62 EEKPEPDISSEESVSTVEEQENETPPATS------SEAEQPKGEPEN--EEKEENKSSEE 113
EEK + SE+ VEEQ ET EA++ +G+ E EE+E EE
Sbjct: 441 EEKIKVVEKSEKETVIVEEQTEETQVTEEVTEEEEKEAKEEEGKEEEGGEEEEAEGGEEE 500
Query: 114 TKKD--EKDQSKEKEKK--VKKTIPSWATLSASQLARAQKQTPMASSPRPKMDA 163
TK E+ S EKE K VK+ S A + + A+ + S + K A
Sbjct: 501 TKSPPAEEAASPEKEAKSPVKEEAKSPAEAKSPEKEEAKSPAEVKSPEKAKSPA 554
Score = 32.7 bits (73), Expect = 0.89
Identities = 36/130 (27%), Positives = 52/130 (40%), Gaps = 20/130 (15%)
Query: 418 SPGVLFPKKEPDDSRDEDEDEDESSEEDSEDEEPPPKRRLQKKTPAKSPGKAASVKQRGS 477
+P PKKE S ++E++ + + + PPK+ ++K PA K K
Sbjct: 809 APEKEIPKKEEVKSPVKEEEKPQEVKV-----KEPPKKAEEEKAPATP--KTEEKKDSKK 861
Query: 478 KPAPKVSAAQRGKARPLPKKAPPKAKTPAKKTRPSSTVIKKPSGGSSKKPAT-----SAR 532
+ APK K P P K K + +K + S KK KK T A+
Sbjct: 862 EEAPK-------KEAPKP-KVEEKKEPAVEKPKESKVEAKKEEAEDKKKVPTPEKEAPAK 913
Query: 533 KEVKLPGKGK 542
EVK K K
Sbjct: 914 VEVKEDAKPK 923
>gi|153945728 microtubule-associated protein 1B [Homo sapiens]
Length = 2468
Score = 58.2 bits (139), Expect = 2e-08
Identities = 39/148 (26%), Positives = 75/148 (50%), Gaps = 11/148 (7%)
Query: 49 RETPPKSKLAEGEEEKPEPDISSEESVSTVEEQENETPPATSSEAE-----QPKGEPENE 103
+ET K + + E+EKP+ +++ +E + ++++E E + + K EP+ E
Sbjct: 640 KETKVKPEDKKEEKEKPKKEVAKKEDKTPIKKEEKPKKEEVKKEVKKEIKKEEKKEPKKE 699
Query: 104 EKEENKSSE---ETKKDEKDQSKEKEKKVKKTI---PSWATLSASQLARAQKQTPMASSP 157
K+E E E KK+EK + K++EK+ KK I P A S++ L+ A+K +
Sbjct: 700 VKKETPPKEVKKEVKKEEKKEVKKEEKEPKKEIKKLPKDAKKSSTPLSEAKKPAALKPKV 759
Query: 158 RPKMDAILTEAIKACFQKSGASVVAIRK 185
K +++ +++ A K + I+K
Sbjct: 760 PKKEESVKKDSVAAGKPKEKGKIKVIKK 787
Score = 44.3 bits (103), Expect = 3e-04
Identities = 50/233 (21%), Positives = 97/233 (41%), Gaps = 31/233 (13%)
Query: 47 STRETPPKSKLAEGEEEKPE----------PDISSEESVSTVEEQ--ENETPPATSSEAE 94
+ + P KS E +EE PE P + S+E V +++ + ET P+ + +
Sbjct: 548 AAKPLPSKSVRKESKEETPEVTKVNHVEKPPKVESKEKVMVKKDKPIKTETKPSVTEKEV 607
Query: 95 QPKGEPE--NEEKEENKSSEETKKDEKDQSKEKEKKVK-KTIPSWATLSASQLARAQKQT 151
K EP E E ++++ K K+++ +KE KVK + ++A+ + +T
Sbjct: 608 PSKEEPSPVKAEVAEKQATDVKPKAAKEKTVKKETKVKPEDKKEEKEKPKKEVAKKEDKT 667
Query: 152 PMASSPRPKMDAILTEAIKACFQKSGASVVAIRKYIIHKYPSLELERRGYLLKQALKREL 211
P+ +PK + + E K ++ K P E+++ + +K+E+
Sbjct: 668 PIKKEEKPKKEEVKKEVKKEIKKEE------------KKEPKKEVKKE--TPPKEVKKEV 713
Query: 212 NRGVIKQVK--GKGASGSFVVVQKSRKTPQKSRNRKNRSSAVDPEPQVKLEDV 262
+ K+VK K + K K + + +A+ P+ K E V
Sbjct: 714 KKEEKKEVKKEEKEPKKEIKKLPKDAKKSSTPLSEAKKPAALKPKVPKKEESV 766
Score = 42.7 bits (99), Expect = 9e-04
Identities = 30/119 (25%), Positives = 56/119 (47%), Gaps = 2/119 (1%)
Query: 429 DDSRDEDEDEDESSEEDSEDEEPPPKRRLQKKTPAKSPGKAASVKQRGSKPAPKVSAAQR 488
++ ++E + E +E ++E+ PK+ ++K+TP K K VK+ K K +
Sbjct: 672 EEKPKKEEVKKEVKKEIKKEEKKEPKKEVKKETPPKEVKK--EVKKEEKKEVKKEEKEPK 729
Query: 489 GKARPLPKKAPPKAKTPAKKTRPSSTVIKKPSGGSSKKPATSARKEVKLPGKGKSTMKK 547
+ + LPK A + ++ +P++ K P S K + A + K GK K K+
Sbjct: 730 KEIKKLPKDAKKSSTPLSEAKKPAALKPKVPKKEESVKKDSVAAGKPKEKGKIKVIKKE 788
Score = 37.7 bits (86), Expect = 0.028
Identities = 23/93 (24%), Positives = 47/93 (50%), Gaps = 4/93 (4%)
Query: 45 VNSTRETPPKSKLAEGEEEKPEPDISSEESVSTVEEQENETPPATSSEA---EQPKGEPE 101
V + ++K + E+E P + S E+Q + P + E ++ K +PE
Sbjct: 588 VKKDKPIKTETKPSVTEKEVPSKEEPSPVKAEVAEKQATDVKPKAAKEKTVKKETKVKPE 647
Query: 102 NEEKEENKSSEET-KKDEKDQSKEKEKKVKKTI 133
++++E+ K +E KK++K K++EK K+ +
Sbjct: 648 DKKEEKEKPKKEVAKKEDKTPIKKEEKPKKEEV 680
Score = 36.6 bits (83), Expect = 0.062
Identities = 41/208 (19%), Positives = 83/208 (39%), Gaps = 11/208 (5%)
Query: 54 KSKLAEGEEEKPEPDISSEESVSTVEEQENETPPATS-SEAEQPKGEPENEEKEENKSSE 112
K K E +P S S +E + ETP T + E+P K E+K
Sbjct: 534 KLKQRADSRESLKPAAKPLPSKSVRKESKEETPEVTKVNHVEKP-------PKVESKEKV 586
Query: 113 ETKKDEKDQSKEKEKKVKKTIPSWATLSASQLARAQKQTPMASSPRPKMDAILTEAIKAC 172
KKD+ +++ K +K +PS S + A+KQ P+ + + + K
Sbjct: 587 MVKKDKPIKTETKPSVTEKEVPSKEEPSPVKAEVAEKQATDV-KPKAAKEKTVKKETKVK 645
Query: 173 FQKSGASVVAIRKYIIHKYPSLELERRGYLLKQALKRELNRGVIKQVK--GKGASGSFVV 230
+ +K + K +++ K+ +K+E+ + + K+ K K
Sbjct: 646 PEDKKEEKEKPKKEVAKKEDKTPIKKEEKPKKEEVKKEVKKEIKKEEKKEPKKEVKKETP 705
Query: 231 VQKSRKTPQKSRNRKNRSSAVDPEPQVK 258
++ +K +K ++ + +P+ ++K
Sbjct: 706 PKEVKKEVKKEEKKEVKKEEKEPKKEIK 733
Score = 36.6 bits (83), Expect = 0.062
Identities = 33/130 (25%), Positives = 49/130 (37%), Gaps = 5/130 (3%)
Query: 425 KKEPDDSRDEDEDEDESSEEDSEDEEPPPKRRLQKKTPAKSPGKAASVKQRGSKPAPKVS 484
K +P+D ++E E + + ED+ P K KK K K K+ +P +V
Sbjct: 643 KVKPEDKKEEKE-KPKKEVAKKEDKTPIKKEEKPKKEEVKKEVKKEIKKEEKKEPKKEVK 701
Query: 485 AAQRGKARPLPKKAPPKAKTPAKKTRPSSTVIKKPSGGS-SKKPATSARKEVKLPGKGKS 543
K K K + ++ P + K P S P + A+K L K
Sbjct: 702 KETPPKEVKKEVKKEEKKEVKKEEKEPKKEIKKLPKDAKKSSTPLSEAKKPAALKPK--- 758
Query: 544 TMKKSFRVKK 553
KK VKK
Sbjct: 759 VPKKEESVKK 768
Score = 36.2 bits (82), Expect = 0.081
Identities = 31/117 (26%), Positives = 46/117 (39%), Gaps = 7/117 (5%)
Query: 438 EDESSEEDSEDEEPPPKRRLQKKTPAKSPGKAASVKQRGSKPAPKVSAAQRGKARPLPKK 497
E + ED ++E+ PK+ + KK K K+ K K + K P K
Sbjct: 641 ETKVKPEDKKEEKEKPKKEVAKKEDKTPIKKEEKPKKEEVKKEVKKEIKKEEKKEP---K 697
Query: 498 APPKAKTPAKKTRPSSTVIKKPSGGSSKKPATSARKEV-KLPGKGKSTMKKSFRVKK 553
K +TP K+ + +KK KK +KE+ KLP K + KK
Sbjct: 698 KEVKKETPPKEVKKE---VKKEEKKEVKKEEKEPKKEIKKLPKDAKKSSTPLSEAKK 751
Score = 35.4 bits (80), Expect = 0.14
Identities = 36/132 (27%), Positives = 55/132 (41%), Gaps = 6/132 (4%)
Query: 426 KEPDDSRDEDEDEDESSEEDSEDEEPPPKRRLQKKTPAKSPGKAASVKQRGSKPAPKVSA 485
K+ + E + E S++E P K + +K KAA K++ K KV
Sbjct: 589 KKDKPIKTETKPSVTEKEVPSKEEPSPVKAEVAEKQATDVKPKAA--KEKTVKKETKVKP 646
Query: 486 AQRGKARPLPKK--APPKAKTPAKK-TRPSSTVIKKPSGGSSKK-PATSARKEVKLPGKG 541
+ + + PKK A + KTP KK +P +KK KK +KEVK
Sbjct: 647 EDKKEEKEKPKKEVAKKEDKTPIKKEEKPKKEEVKKEVKKEIKKEEKKEPKKEVKKETPP 706
Query: 542 KSTMKKSFRVKK 553
K K+ + +K
Sbjct: 707 KEVKKEVKKEEK 718
Score = 33.1 bits (74), Expect = 0.68
Identities = 31/108 (28%), Positives = 45/108 (41%), Gaps = 14/108 (12%)
Query: 430 DSRDEDEDEDESSEEDSE---DEEPPPKRRLQKKTPAKSPGKAASVKQRGSKPAPKVSAA 486
D+ + EDE E+ D PP +Q ++P+ + V P+ A
Sbjct: 2175 DANIDSEDESETIPTDKTVTYKHMDPPPAPVQDRSPSPRHPDVSMVD-------PEALAI 2227
Query: 487 QRGKARPLPKKAPPKAKT--PAKKTRPSSTVIKKPSGGSSKKPATSAR 532
++ + L K K KT P KT+ SS V K S G SK A S +
Sbjct: 2228 EQNLGKALKKDLKEKTKTKKPGTKTKSSSPV--KKSDGKSKPLAASPK 2273
Score = 33.1 bits (74), Expect = 0.68
Identities = 29/106 (27%), Positives = 45/106 (42%), Gaps = 4/106 (3%)
Query: 443 EEDSEDEEPPPKRRLQ---KKTPAKSPGKAASVKQRGSKPAP-KVSAAQRGKARPLPKKA 498
+E ++ ++P K + KK+ KS AAS K G K + KVS K + +KA
Sbjct: 2240 KEKTKTKKPGTKTKSSSPVKKSDGKSKPLAASPKPAGLKESSDKVSRVASPKKKESVEKA 2299
Query: 499 PPKAKTPAKKTRPSSTVIKKPSGGSSKKPATSARKEVKLPGKGKST 544
TP K K+ ++ + SA+ PG K+T
Sbjct: 2300 AKPTTTPEVKAARGEEKDKETKNAANASASKSAKTATAGPGTTKTT 2345
Score = 32.3 bits (72), Expect = 1.2
Identities = 24/93 (25%), Positives = 38/93 (40%), Gaps = 6/93 (6%)
Query: 460 KTPAKSPGKAASVKQRGSKPAPKVSAAQRGKARPLPKKAPPKAKTPAKKTRPSSTVIKKP 519
KT + SP K + K + +PK + + + +P K ++ K +P++T K
Sbjct: 2251 KTKSSSPVKKSDGKSKPLAASPKPAGLKESSDKVSRVASPKKKESVEKAAKPTTTPEVKA 2310
Query: 520 SGGSSKKPAT------SARKEVKLPGKGKSTMK 546
+ G K T SA K K G T K
Sbjct: 2311 ARGEEKDKETKNAANASASKSAKTATAGPGTTK 2343
Score = 31.2 bits (69), Expect = 2.6
Identities = 24/88 (27%), Positives = 39/88 (44%), Gaps = 6/88 (6%)
Query: 50 ETPPKSKLAEGEE-EKPEPDISSEESVSTVEEQENETPPATSSEA-----EQPKGEPENE 103
ET + AE EE E+PE D VS + E + +EA E+ + +
Sbjct: 938 ETGDYEEKAETEEAEEPEEDGEEHVCVSASKHSPTEDEESAKAEADAYIREKRESVASGD 997
Query: 104 EKEENKSSEETKKDEKDQSKEKEKKVKK 131
++ E E +K E +QS+E+ + K
Sbjct: 998 DRAEEDMDEAIEKGEAEQSEEEADEEDK 1025
>gi|4885371 H1 histone family, member 0 [Homo sapiens]
Length = 194
Score = 54.3 bits (129), Expect = 3e-07
Identities = 46/169 (27%), Positives = 83/169 (49%), Gaps = 13/169 (7%)
Query: 346 ILSAIAAMNEPKTCSTTALKKYVLENHP-GTNSNYQMHLLKKTLQKCEKNGWMEQISGKG 404
I++AI A S +++KY+ ++ G N++ Q +K ++++ G ++Q G G
Sbjct: 32 IVAAIQAEKNRAGSSRQSIQKYIKSHYKVGENADSQ---IKLSIKRLVTTGVLKQTKGVG 88
Query: 405 FSGTFQLCFPYYPSPGVLFPK-----KEPDDSRDEDEDEDESSEEDSEDEEPPPKRRLQK 459
SG+F+L P V F K K+ + + + +S+ ++ + P ++ +K
Sbjct: 89 ASGSFRLAKSDEPKKSVAFKKTKKEIKKVATPKKASKPKKAASKAPTKKPKATPVKKAKK 148
Query: 460 KTPAKSPGKAASVKQRGSKPAPKVSAAQRGKARPLPKKAPPKAKTPAKK 508
K A +P KA K +KP V A++ KA+P+ KA AK KK
Sbjct: 149 KLAA-TPKKAKKPKTVKAKP---VKASKPKKAKPVKPKAKSSAKRAGKK 193
Score = 50.8 bits (120), Expect = 3e-06
Identities = 54/183 (29%), Positives = 86/183 (46%), Gaps = 27/183 (14%)
Query: 145 ARAQKQTPMASSPRPKMDAILTEAIKACFQKSGASVVAIRKYIIHKYPSLELERRGYLLK 204
A+A K+ S+ PK ++ AI+A ++G+S +I+KYI Y E +K
Sbjct: 16 AKASKK----STDHPKYSDMIVAAIQAEKNRAGSSRQSIQKYIKSHYKVGE--NADSQIK 69
Query: 205 QALKRELNRGVIKQVKGKGASGSF-----------VVVQKSRK------TPQKSRNRKNR 247
++KR + GV+KQ KG GASGSF V +K++K TP+K+ K
Sbjct: 70 LSIKRLVTTGVLKQTKGVGASGSFRLAKSDEPKKSVAFKKTKKEIKKVATPKKASKPKKA 129
Query: 248 SSAVDPEPQVKLEDVLPLAFTRLCEPKEAS--YSLIRKYVSQYYPKLRVDIRPQLLKNAL 305
+S P + K V PK+A ++ K V PK ++P+ K++
Sbjct: 130 ASKA-PTKKPKATPVKKAKKKLAATPKKAKKPKTVKAKPVKASKPKKAKPVKPK-AKSSA 187
Query: 306 QRA 308
+RA
Sbjct: 188 KRA 190
Score = 39.3 bits (90), Expect = 0.010
Identities = 31/104 (29%), Positives = 48/104 (46%), Gaps = 4/104 (3%)
Query: 230 VVQKSRKTPQKSRNRKNRSSAVDPEPQVKLEDVLPLAFTRLCEPKEASYSLIRKYVSQYY 289
+ + S P R S P K D++ A +S I+KY+ +Y
Sbjct: 1 MTENSTSAPAAKPKRAKASKKSTDHP--KYSDMIVAAIQAEKNRAGSSRQSIQKYIKSHY 58
Query: 290 PKLRVDIRPQLLKNALQRAVERGQLEQITGKGASGTFQLKKSGE 333
K+ + Q+ K +++R V G L+Q G GASG+F+L KS E
Sbjct: 59 -KVGENADSQI-KLSIKRLVTTGVLKQTKGVGASGSFRLAKSDE 100
>gi|104526627 triadin [Homo sapiens]
Length = 729
Score = 54.3 bits (129), Expect = 3e-07
Identities = 123/577 (21%), Positives = 205/577 (35%), Gaps = 90/577 (15%)
Query: 4 DTSQGELVHPKALPLIVGAQLIHADKLGEKVEDSTMPIRRTVNSTRETPPKSKLAEGEEE 63
DT +GE+ P + + IH DK EK E I+ V + K K+ E +E
Sbjct: 127 DTDKGEIDEPP-----LRKKEIHKDKT-EKQEKPERKIQTKVTHKEKEKGKEKVRE--KE 178
Query: 64 KPEPDISSEESVSTVEEQENETPPATSSEAEQPKGEPENEEKEENKSSEE--------TK 115
KPE + +E + E+ E +T +A+ + E +KE +E K
Sbjct: 179 KPEKKATHKEKIEKKEKPETKTLAKEQKKAKTAEKSEEKTKKEVKGGKQEKVKQTAAKVK 238
Query: 116 KDEKDQSKEKEKKVKKTIPSWATLSASQLARAQ-------------KQTPMASSPRPKMD 162
+ +K SK KEK+ K+ Q A + Q+P P P
Sbjct: 239 EVQKTPSKPKEKEDKEKAAVSKHEQKDQYAFCRYMIDIFVHGDLKPGQSPAIPPPLPTEQ 298
Query: 163 AIL-TEAIKACFQKSGASVVAIRKYIIHKYPSLELERRGYLLKQALKRELNRGVIKQVKG 221
A T A A +K G +K K S ++ +K+ ++E V K+ G
Sbjct: 299 ASRPTPASPALEEKEGE-----KKKAEKKVTSETKKKEKEDIKKKSEKETAIDVEKKEPG 353
Query: 222 KGASGSFVVVQ-----KSRKTPQKSRNRKNRSSAVDPEPQVKLEDVLPLAFTRLCEPKEA 276
K + V+ ++K +K ++K + A +P+ K ++ PK+
Sbjct: 354 KASETKQGTVKIAAQAAAKKDEKKEDSKKTKKPAEVEQPKGKKQEKKEKHVEPAKSPKKE 413
Query: 277 SYSLIRKYVSQYYPKLRVDIRPQLLKNALQRAVERGQLEQITGKGASGTFQLKKSGEKPL 336
K V + + +I +K A+ G+ E+ T K + +KSG+
Sbjct: 414 HSVPSDKQVKAKTERAKEEIGAVSIKKAVP-----GKKEEKTTKTVEQEIRKEKSGK--- 465
Query: 337 LGGSLMEYAILSAIAAMNEPKTCSTTALKKYVLENHPGTNSNYQMHLLKKTLQKCEKNGW 396
S+I EP + + E P T + +M K E
Sbjct: 466 ----------TSSILKDKEPIKGKEEKVPASLKEKEPETKKDEKMSKAGK-----EVKPK 510
Query: 397 MEQISGKGFSGTFQLCFPYYPSPGVLFPKKEPDDSRDEDEDEDESSEEDSEDEEPPPKRR 456
Q+ GK P P + K + + +D E + P ++
Sbjct: 511 PPQLQGKK---------EEKPEPQIKKEAKPAISEKVQIHKQDIVKPEKTVSHGKPEEKV 561
Query: 457 LQKKTPAKSPGKAASVKQRGSKPAPKVSAAQRGKARPLPKKAPPKAKTPAKKTRPSSTVI 516
L++ KA ++ ++ +KP P A R ++ PP KT K P T
Sbjct: 562 LKQV-------KAVTI-EKTAKPKPTKKAEHR-------EREPPSIKTDKPKPTPKGTSE 606
Query: 517 KKPSGGSSKKPATSARKEVKLPGKGKSTMKKSFRVKK 553
SG KK + KE K K ++ +K
Sbjct: 607 VTESG---KKKTEISEKESKEKADMKHLREEKVSTRK 640
Score = 47.4 bits (111), Expect = 3e-05
Identities = 36/142 (25%), Positives = 64/142 (45%), Gaps = 24/142 (16%)
Query: 421 VLFPKKEPDDSRDEDEDEDESSE---------EDSEDEEPPPKRRLQKKTPAKSPGKAAS 471
++ + E DD DED D+ E E +D +++ P+R++Q K K K
Sbjct: 113 IISSEDEEDDDGDEDTDKGEIDEPPLRKKEIHKDKTEKQEKPERKIQTKVTHKEKEKGKE 172
Query: 472 VKQRGSKPAPKVSAAQRGKARPLPKKAPPKAKTPAKKTRPSSTVIKKPSGGSSKKPATSA 531
+ KP K + ++ + KK P+ KT AK+ + + T ++K
Sbjct: 173 KVREKEKPEKKATHKEK-----IEKKEKPETKTLAKEQKKAKT---------AEKSEEKT 218
Query: 532 RKEVKLPGKGKSTMKKSFRVKK 553
+KEVK GK + + + +VK+
Sbjct: 219 KKEVK-GGKQEKVKQTAAKVKE 239
Score = 34.3 bits (77), Expect = 0.31
Identities = 37/136 (27%), Positives = 51/136 (37%), Gaps = 17/136 (12%)
Query: 44 TVNSTRETPPKSKLAEGEEEKPEPDISSEESVSTVEEQENETPPATSSEAEQPKGEPENE 103
T+ T + P K E E P S+ T ++ TP TS E K + E
Sbjct: 569 TIEKTAKPKPTKKAEHREREPP--------SIKT--DKPKPTPKGTSEVTESGKKKTEIS 618
Query: 104 EKEENKSSEETKKDEKDQSKEKEKKVKKTIPSWATLSASQLARAQKQTPMASSPRPKMDA 163
EKE + K D K +EK K+++ A + AR K + P K
Sbjct: 619 EKESKE-----KADMKHLREEKVSTRKESLQLHNVTKAEKPARVSKD--VEDVPASKKAK 671
Query: 164 ILTEAIKACFQKSGAS 179
TE + QKS S
Sbjct: 672 EGTEDVSPTKQKSPIS 687
>gi|17975763 myelin transcription factor 1 [Homo sapiens]
Length = 1121
Score = 53.9 bits (128), Expect = 4e-07
Identities = 45/168 (26%), Positives = 75/168 (44%), Gaps = 12/168 (7%)
Query: 4 DTSQGELVHPKALPLIVGAQLIHADKLGEK-----VEDSTMPIRRTVNSTRETPPKS-KL 57
D Q P + L+ A A + GEK ED+ + T +++ P+S +
Sbjct: 183 DLGQAAKPGPGIVHLLQEAAEGAASEEGEKGLFIQPEDAEEVVEVTTERSQDLCPQSLED 242
Query: 58 AEGEEEKPEPDISSEESVSTVEEQENETPPATSSEAEQPKGEPENEEKEENKSSEETKKD 117
A EE + I S E EE+E E E E + E E EE+EE + EE +++
Sbjct: 243 AASEESSKQKGILSHEEEDEEEEEEEE------EEEEDEEEEEEEEEEEEEEEEEEEEEE 296
Query: 118 EKDQSKEKEKKVKKTIPSWATLSASQLARAQKQTPMASSPRPKMDAIL 165
E+++ +E+E+ I T S + + P + SP+P+ I+
Sbjct: 297 EEEEEEEEEEAAPDVIFQEDTSHTSAQKAPELRGPESPSPKPEYSVIV 344
Score = 39.3 bits (90), Expect = 0.010
Identities = 26/114 (22%), Positives = 52/114 (45%), Gaps = 6/114 (5%)
Query: 420 GVLFPKKEPDDSRDEDEDEDESSEEDSEDEEPPPKRRLQKKTPAKSPGKAASVKQRGSKP 479
G+L ++E ++ +E+E+E+E EE+ E+EE + +++ + ++ +
Sbjct: 253 GILSHEEEDEEEEEEEEEEEEDEEEEEEEEEEEEEEEEEEEEEEEE-----EEEEEEEEA 307
Query: 480 APKVSAAQRGKARPLPKKAPPKAKTPAKKTRPSSTVIKKPSGGSSKKPATSARK 533
AP V Q + +KAP + +P +VI + K T +RK
Sbjct: 308 APDV-IFQEDTSHTSAQKAPELRGPESPSPKPEYSVIVEVRSDDDKDEDTHSRK 360
>gi|157738649 neurofilament, medium polypeptide 150kDa isoform 1
[Homo sapiens]
Length = 916
Score = 52.4 bits (124), Expect = 1e-06
Identities = 39/130 (30%), Positives = 65/130 (50%), Gaps = 12/130 (9%)
Query: 434 EDEDEDESSEEDSEDEEPPPKRRLQKKTPAKSPGKAASVKQRGSKPAPKVSAAQRGKARP 493
E++ +E SEE + EE +++K AKSP + V+++G P PK ++GK+ P
Sbjct: 584 EEKKVEEKSEEVATKEELVADAKVEKPEKAKSPVPKSPVEEKGKSPVPKSPVEEKGKS-P 642
Query: 494 LPK-------KAP-PKAKTPAKKTRP--SSTVIKKPSGGSSKKPATSARKEVKLPGKGKS 543
+PK K+P PK+ K P S V +K K P A+ + ++ GKG+
Sbjct: 643 VPKSPVEEKGKSPVPKSPVEEKGKSPVSKSPVEEKAKSPVPKSPVEEAKSKAEV-GKGEQ 701
Query: 544 TMKKSFRVKK 553
++ VK+
Sbjct: 702 KEEEEKEVKE 711
Score = 50.4 bits (119), Expect = 4e-06
Identities = 83/392 (21%), Positives = 154/392 (39%), Gaps = 41/392 (10%)
Query: 27 ADKLGEKVEDSTMPIRRTVNSTRETPPKSKLAEGEEEKPEPDISSEESVSTVEEQENETP 86
A++ E+ E + + + T P+ K EGE+E+ E EE+E E
Sbjct: 492 AEEKEEEPEAEEEEVAAKKSPVKATAPEVKEEEGEKEEEEGQ----------EEEEEEDE 541
Query: 87 PATSSEAE----QPKGEPENEEKEENKSSEETKKDEKDQSKEKEKKVKKTIPSWATLSAS 142
A S +AE + +G E EE E+ + E + + ++ ++EKKV++ AT
Sbjct: 542 GAKSDQAEEGGSEKEGSSEKEEGEQEEGETEAEAEGEEAEAKEEKKVEEKSEEVAT-KEE 600
Query: 143 QLARAQKQTP-MASSPRPKM---DAILTEAIKACFQKSGASVV---AIRKYIIHKYPSLE 195
+A A+ + P A SP PK + + K+ ++ G S V + + P
Sbjct: 601 LVADAKVEKPEKAKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVPKSP 660
Query: 196 LERRGYL------LKQALKRELNRGVIKQVKGKGASGSFVVVQKSRK----TPQKSRNRK 245
+E +G +++ K + + +++ K K G ++ K P++ + K
Sbjct: 661 VEEKGKSPVSKSPVEEKAKSPVPKSPVEEAKSKAEVGKGEQKEEEEKEVKEAPKEEKVEK 720
Query: 246 NRSSAVDPEPQVKLEDVLPLAFTRLCEPKEASYSLIRKYVSQYYPK-LRVDIRP-QLLKN 303
D + K E + E A I K V + K + + +P Q K
Sbjct: 721 KEEKPKDVPEKKKAESPVK-------EEAVAEVVTITKSVKVHLEKETKEEGKPLQQEKE 773
Query: 304 ALQRAVERGQLEQITGKGASGTFQLKKSGEKPLLGGSLMEYAILSAIAAMNEPKTCSTTA 363
+ E G E+ + KGA G+ + + + G +E + E K T
Sbjct: 774 KEKAGGEGGSEEEGSDKGAKGSRKEDIAVNGEVEGKEEVEQETKEKGSGREEEKGVVTNG 833
Query: 364 LKKYVLENHPGTNSNYQMHLLKKTLQKCEKNG 395
L + G + + + ++ KT++K G
Sbjct: 834 LDLSPADEKKGGDKSEEKVVVTKTVEKITSEG 865
Score = 35.4 bits (80), Expect = 0.14
Identities = 31/135 (22%), Positives = 51/135 (37%), Gaps = 10/135 (7%)
Query: 424 PKKEPDDSRDEDEDEDESSEEDSEDEEPPPKRRLQKKTPAKSPGKAASVKQRGSKPAPKV 483
P K E+E E E E E+EE + + S + +S K+ G + +
Sbjct: 512 PVKATAPEVKEEEGEKEEEEGQEEEEEEDEGAKSDQAEEGGSEKEGSSEKEEGEQEEGET 571
Query: 484 SAAQRG---KARPLPKKAPPKAKTPAKKTRPSSTVIKKPSGGSSKKPATSARKEVKLP-- 538
A G +A+ K + K+ + ++KP S P + ++ K P
Sbjct: 572 EAEAEGEEAEAKEEKKVEEKSEEVATKEELVADAKVEKPEKAKSPVPKSPVEEKGKSPVP 631
Query: 539 -----GKGKSTMKKS 548
KGKS + KS
Sbjct: 632 KSPVEEKGKSPVPKS 646
Score = 33.1 bits (74), Expect = 0.68
Identities = 29/112 (25%), Positives = 52/112 (46%), Gaps = 8/112 (7%)
Query: 31 GEKVEDSTMPIRRTVNSTRETPP---KSKLAEGEEEKPEPDISS---EESV--STVEEQE 82
GE+ ST T PP SK+ + + E P+ + EE + + VE+++
Sbjct: 407 GEETRFSTFAGSITGPLYTHRPPITISSKIQKPKVEAPKLKVQHKFVEEIIEETKVEDEK 466
Query: 83 NETPPATSSEAEQPKGEPENEEKEENKSSEETKKDEKDQSKEKEKKVKKTIP 134
+E A ++ E+ + E+KE + EE + E+++ K+ VK T P
Sbjct: 467 SEMEEALTAITEELAVSMKEEKKEAAEEKEEEPEAEEEEVAAKKSPVKATAP 518
Score = 33.1 bits (74), Expect = 0.68
Identities = 26/101 (25%), Positives = 44/101 (43%), Gaps = 14/101 (13%)
Query: 442 SEEDSEDEEPPPKRRLQKKTPAKSPGKAASVKQRGSKPAPK------VSAAQRGKARPLP 495
S + + + P PK +++K KSP + V+++ P PK S A+ GK
Sbjct: 646 SPVEEKGKSPVPKSPVEEK--GKSPVSKSPVEEKAKSPVPKSPVEEAKSKAEVGKGEQKE 703
Query: 496 ------KKAPPKAKTPAKKTRPSSTVIKKPSGGSSKKPATS 530
K+AP + K K+ +P KK + K+ A +
Sbjct: 704 EEEKEVKEAPKEEKVEKKEEKPKDVPEKKKAESPVKEEAVA 744
Score = 30.4 bits (67), Expect = 4.4
Identities = 25/82 (30%), Positives = 41/82 (50%), Gaps = 15/82 (18%)
Query: 61 EEEKPEPDISS-EESVSTVEEQENETPPATSSEA-EQPKGEPENEEKE------------ 106
EE K E + S EE+++ + E+ + EA E+ + EPE EE+E
Sbjct: 458 EETKVEDEKSEMEEALTAITEELAVSMKEEKKEAAEEKEEEPEAEEEEVAAKKSPVKATA 517
Query: 107 -ENKSSEETKKDEKDQSKEKEK 127
E K E K++E+ Q +E+E+
Sbjct: 518 PEVKEEEGEKEEEEGQEEEEEE 539
>gi|157738641 neurofilament, medium polypeptide 150kDa isoform 2
[Homo sapiens]
Length = 540
Score = 52.4 bits (124), Expect = 1e-06
Identities = 39/130 (30%), Positives = 65/130 (50%), Gaps = 12/130 (9%)
Query: 434 EDEDEDESSEEDSEDEEPPPKRRLQKKTPAKSPGKAASVKQRGSKPAPKVSAAQRGKARP 493
E++ +E SEE + EE +++K AKSP + V+++G P PK ++GK+ P
Sbjct: 208 EEKKVEEKSEEVATKEELVADAKVEKPEKAKSPVPKSPVEEKGKSPVPKSPVEEKGKS-P 266
Query: 494 LPK-------KAP-PKAKTPAKKTRP--SSTVIKKPSGGSSKKPATSARKEVKLPGKGKS 543
+PK K+P PK+ K P S V +K K P A+ + ++ GKG+
Sbjct: 267 VPKSPVEEKGKSPVPKSPVEEKGKSPVSKSPVEEKAKSPVPKSPVEEAKSKAEV-GKGEQ 325
Query: 544 TMKKSFRVKK 553
++ VK+
Sbjct: 326 KEEEEKEVKE 335
Score = 50.4 bits (119), Expect = 4e-06
Identities = 83/392 (21%), Positives = 154/392 (39%), Gaps = 41/392 (10%)
Query: 27 ADKLGEKVEDSTMPIRRTVNSTRETPPKSKLAEGEEEKPEPDISSEESVSTVEEQENETP 86
A++ E+ E + + + T P+ K EGE+E+ E EE+E E
Sbjct: 116 AEEKEEEPEAEEEEVAAKKSPVKATAPEVKEEEGEKEEEEGQ----------EEEEEEDE 165
Query: 87 PATSSEAE----QPKGEPENEEKEENKSSEETKKDEKDQSKEKEKKVKKTIPSWATLSAS 142
A S +AE + +G E EE E+ + E + + ++ ++EKKV++ AT
Sbjct: 166 GAKSDQAEEGGSEKEGSSEKEEGEQEEGETEAEAEGEEAEAKEEKKVEEKSEEVAT-KEE 224
Query: 143 QLARAQKQTP-MASSPRPKM---DAILTEAIKACFQKSGASVV---AIRKYIIHKYPSLE 195
+A A+ + P A SP PK + + K+ ++ G S V + + P
Sbjct: 225 LVADAKVEKPEKAKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVPKSP 284
Query: 196 LERRGYL------LKQALKRELNRGVIKQVKGKGASGSFVVVQKSRK----TPQKSRNRK 245
+E +G +++ K + + +++ K K G ++ K P++ + K
Sbjct: 285 VEEKGKSPVSKSPVEEKAKSPVPKSPVEEAKSKAEVGKGEQKEEEEKEVKEAPKEEKVEK 344
Query: 246 NRSSAVDPEPQVKLEDVLPLAFTRLCEPKEASYSLIRKYVSQYYPK-LRVDIRP-QLLKN 303
D + K E + E A I K V + K + + +P Q K
Sbjct: 345 KEEKPKDVPEKKKAESPVK-------EEAVAEVVTITKSVKVHLEKETKEEGKPLQQEKE 397
Query: 304 ALQRAVERGQLEQITGKGASGTFQLKKSGEKPLLGGSLMEYAILSAIAAMNEPKTCSTTA 363
+ E G E+ + KGA G+ + + + G +E + E K T
Sbjct: 398 KEKAGGEGGSEEEGSDKGAKGSRKEDIAVNGEVEGKEEVEQETKEKGSGREEEKGVVTNG 457
Query: 364 LKKYVLENHPGTNSNYQMHLLKKTLQKCEKNG 395
L + G + + + ++ KT++K G
Sbjct: 458 LDLSPADEKKGGDKSEEKVVVTKTVEKITSEG 489
Score = 35.4 bits (80), Expect = 0.14
Identities = 31/135 (22%), Positives = 51/135 (37%), Gaps = 10/135 (7%)
Query: 424 PKKEPDDSRDEDEDEDESSEEDSEDEEPPPKRRLQKKTPAKSPGKAASVKQRGSKPAPKV 483
P K E+E E E E E+EE + + S + +S K+ G + +
Sbjct: 136 PVKATAPEVKEEEGEKEEEEGQEEEEEEDEGAKSDQAEEGGSEKEGSSEKEEGEQEEGET 195
Query: 484 SAAQRG---KARPLPKKAPPKAKTPAKKTRPSSTVIKKPSGGSSKKPATSARKEVKLP-- 538
A G +A+ K + K+ + ++KP S P + ++ K P
Sbjct: 196 EAEAEGEEAEAKEEKKVEEKSEEVATKEELVADAKVEKPEKAKSPVPKSPVEEKGKSPVP 255
Query: 539 -----GKGKSTMKKS 548
KGKS + KS
Sbjct: 256 KSPVEEKGKSPVPKS 270
Score = 33.1 bits (74), Expect = 0.68
Identities = 29/112 (25%), Positives = 52/112 (46%), Gaps = 8/112 (7%)
Query: 31 GEKVEDSTMPIRRTVNSTRETPP---KSKLAEGEEEKPEPDISS---EESV--STVEEQE 82
GE+ ST T PP SK+ + + E P+ + EE + + VE+++
Sbjct: 31 GEETRFSTFAGSITGPLYTHRPPITISSKIQKPKVEAPKLKVQHKFVEEIIEETKVEDEK 90
Query: 83 NETPPATSSEAEQPKGEPENEEKEENKSSEETKKDEKDQSKEKEKKVKKTIP 134
+E A ++ E+ + E+KE + EE + E+++ K+ VK T P
Sbjct: 91 SEMEEALTAITEELAVSMKEEKKEAAEEKEEEPEAEEEEVAAKKSPVKATAP 142
Score = 33.1 bits (74), Expect = 0.68
Identities = 26/101 (25%), Positives = 44/101 (43%), Gaps = 14/101 (13%)
Query: 442 SEEDSEDEEPPPKRRLQKKTPAKSPGKAASVKQRGSKPAPK------VSAAQRGKARPLP 495
S + + + P PK +++K KSP + V+++ P PK S A+ GK
Sbjct: 270 SPVEEKGKSPVPKSPVEEK--GKSPVSKSPVEEKAKSPVPKSPVEEAKSKAEVGKGEQKE 327
Query: 496 ------KKAPPKAKTPAKKTRPSSTVIKKPSGGSSKKPATS 530
K+AP + K K+ +P KK + K+ A +
Sbjct: 328 EEEKEVKEAPKEEKVEKKEEKPKDVPEKKKAESPVKEEAVA 368
Score = 30.4 bits (67), Expect = 4.4
Identities = 25/82 (30%), Positives = 41/82 (50%), Gaps = 15/82 (18%)
Query: 61 EEEKPEPDISS-EESVSTVEEQENETPPATSSEA-EQPKGEPENEEKE------------ 106
EE K E + S EE+++ + E+ + EA E+ + EPE EE+E
Sbjct: 82 EETKVEDEKSEMEEALTAITEELAVSMKEEKKEAAEEKEEEPEAEEEEVAAKKSPVKATA 141
Query: 107 -ENKSSEETKKDEKDQSKEKEK 127
E K E K++E+ Q +E+E+
Sbjct: 142 PEVKEEEGEKEEEEGQEEEEEE 163
>gi|148763345 cell division cycle 2-like 2 isoform 4 [Homo sapiens]
Length = 770
Score = 50.1 bits (118), Expect = 5e-06
Identities = 28/108 (25%), Positives = 53/108 (49%), Gaps = 5/108 (4%)
Query: 52 PPKSKLAEGEEEKPEPDISSEE-----SVSTVEEQENETPPATSSEAEQPKGEPENEEKE 106
PP+ + G+ KP + EE + + + E +T A SS AE G E EE+E
Sbjct: 226 PPRERFELGDGRKPVKEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEE 285
Query: 107 ENKSSEETKKDEKDQSKEKEKKVKKTIPSWATLSASQLARAQKQTPMA 154
E + E + +E ++ +E+E++ ++ S + ++ Q A + M+
Sbjct: 286 EEEEEEGSTSEESEEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEMS 333
Score = 44.3 bits (103), Expect = 3e-04
Identities = 31/123 (25%), Positives = 55/123 (44%), Gaps = 14/123 (11%)
Query: 32 EKVEDSTMPIRRTVNSTRETPPKSKLAEGEEEKPEPDISSEESVSTVEEQENETPPATSS 91
+ + DS +S+ E+ S+ E EEE+ E + S+ E EE+E E T S
Sbjct: 255 QDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGS 314
Query: 92 EAEQPKGEPENEEKEENKSSEETKKDE--------------KDQSKEKEKKVKKTIPSWA 137
+E+ + E EE S +E +++E +S+E E++V + P +
Sbjct: 315 NSEEASEQSAEEVSEEEMSEDEERENENHLLVVPESRFDRDSGESEEAEEEVGEGTPQSS 374
Query: 138 TLS 140
L+
Sbjct: 375 ALT 377
Score = 40.4 bits (93), Expect = 0.004
Identities = 29/113 (25%), Positives = 55/113 (48%), Gaps = 12/113 (10%)
Query: 21 GAQLIHADKLGEK-----VEDSTMPIRRTVNSTRETPPKSKLAEGEEEKPEPDISSEESV 75
G + + +K+ E+ ++D + R+T ++ + +E EEE+ E + EE
Sbjct: 236 GRKPVKEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEE---EEEG 292
Query: 76 STVEEQENETPPATSSEAEQPKGEPENEEKEENKSSEETKKDEKDQSKEKEKK 128
ST EE E E E E+ + N E+ +S+EE ++E + +E+E +
Sbjct: 293 STSEESEEE----EEEEEEEEEETGSNSEEASEQSAEEVSEEEMSEDEERENE 341
Score = 31.6 bits (70), Expect = 2.0
Identities = 26/104 (25%), Positives = 43/104 (41%), Gaps = 6/104 (5%)
Query: 28 DKLGEKVEDSTMPIRRTVNSTRETPPKSKLAEGEEEKPEPDISSEESVSTVEEQENETPP 87
+K K ++ I+R NS + L EGE +I+ S E+ +
Sbjct: 19 EKKRRKEQEEKAEIKRLKNSDDRDSKRDSLEEGELRDHCMEITIRNSPYRREDSMEDRGE 78
Query: 88 ATSSEAEQPKGEPENEEKEENKSSEETKKDEKDQSKEKEKKVKK 131
S A +P + +EK + +KDEK + K K +VK+
Sbjct: 79 EDDSLAIKPPQQMSRKEKVHH------RKDEKRKEKWKHARVKE 116
>gi|148763347 cell division cycle 2-like 2 isoform 1 [Homo sapiens]
Length = 780
Score = 50.1 bits (118), Expect = 5e-06
Identities = 28/108 (25%), Positives = 53/108 (49%), Gaps = 5/108 (4%)
Query: 52 PPKSKLAEGEEEKPEPDISSEE-----SVSTVEEQENETPPATSSEAEQPKGEPENEEKE 106
PP+ + G+ KP + EE + + + E +T A SS AE G E EE+E
Sbjct: 236 PPRERFELGDGRKPVKEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEE 295
Query: 107 ENKSSEETKKDEKDQSKEKEKKVKKTIPSWATLSASQLARAQKQTPMA 154
E + E + +E ++ +E+E++ ++ S + ++ Q A + M+
Sbjct: 296 EEEEEEGSTSEESEEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEMS 343
Score = 44.3 bits (103), Expect = 3e-04
Identities = 31/123 (25%), Positives = 55/123 (44%), Gaps = 14/123 (11%)
Query: 32 EKVEDSTMPIRRTVNSTRETPPKSKLAEGEEEKPEPDISSEESVSTVEEQENETPPATSS 91
+ + DS +S+ E+ S+ E EEE+ E + S+ E EE+E E T S
Sbjct: 265 QDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGS 324
Query: 92 EAEQPKGEPENEEKEENKSSEETKKDE--------------KDQSKEKEKKVKKTIPSWA 137
+E+ + E EE S +E +++E +S+E E++V + P +
Sbjct: 325 NSEEASEQSAEEVSEEEMSEDEERENENHLLVVPESRFDRDSGESEEAEEEVGEGTPQSS 384
Query: 138 TLS 140
L+
Sbjct: 385 ALT 387
Score = 40.4 bits (93), Expect = 0.004
Identities = 29/113 (25%), Positives = 55/113 (48%), Gaps = 12/113 (10%)
Query: 21 GAQLIHADKLGEK-----VEDSTMPIRRTVNSTRETPPKSKLAEGEEEKPEPDISSEESV 75
G + + +K+ E+ ++D + R+T ++ + +E EEE+ E + EE
Sbjct: 246 GRKPVKEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEE---EEEG 302
Query: 76 STVEEQENETPPATSSEAEQPKGEPENEEKEENKSSEETKKDEKDQSKEKEKK 128
ST EE E E E E+ + N E+ +S+EE ++E + +E+E +
Sbjct: 303 STSEESEEE----EEEEEEEEEETGSNSEEASEQSAEEVSEEEMSEDEERENE 351
Score = 30.8 bits (68), Expect = 3.4
Identities = 21/94 (22%), Positives = 39/94 (41%)
Query: 35 EDSTMPIRRTVNSTRETPPKSKLAEGEEEKPEPDISSEESVSTVEEQENETPPATSSEAE 94
ED ++ I+ +R+ + E +EK S E +E E E
Sbjct: 79 EDDSLAIKPPQQMSRKEKVHHRKDEKRKEKCRHHSHSAEGGKHARVKEREHERRKRHREE 138
Query: 95 QPKGEPENEEKEENKSSEETKKDEKDQSKEKEKK 128
Q K E E ++ + + E + E+D+ ++ E+K
Sbjct: 139 QDKARREWERQKRREMAREHSRRERDRLEQLERK 172
>gi|16332372 cell division cycle 2-like 1 (PITSLRE proteins) isoform
9 [Homo sapiens]
Length = 771
Score = 50.1 bits (118), Expect = 5e-06
Identities = 28/108 (25%), Positives = 53/108 (49%), Gaps = 5/108 (4%)
Query: 52 PPKSKLAEGEEEKPEPDISSEE-----SVSTVEEQENETPPATSSEAEQPKGEPENEEKE 106
PP+ + G+ KP + EE + + + E +T A SS AE G E EE+E
Sbjct: 227 PPRERFELGDGRKPVKEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEE 286
Query: 107 ENKSSEETKKDEKDQSKEKEKKVKKTIPSWATLSASQLARAQKQTPMA 154
E + E + +E ++ +E+E++ ++ S + ++ Q A + M+
Sbjct: 287 EEEEEEGSTSEESEEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEMS 334
Score = 44.3 bits (103), Expect = 3e-04
Identities = 31/123 (25%), Positives = 55/123 (44%), Gaps = 14/123 (11%)
Query: 32 EKVEDSTMPIRRTVNSTRETPPKSKLAEGEEEKPEPDISSEESVSTVEEQENETPPATSS 91
+ + DS +S+ E+ S+ E EEE+ E + S+ E EE+E E T S
Sbjct: 256 QDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGS 315
Query: 92 EAEQPKGEPENEEKEENKSSEETKKDE--------------KDQSKEKEKKVKKTIPSWA 137
+E+ + E EE S +E +++E +S+E E++V + P +
Sbjct: 316 NSEEASEQSAEEVSEEEMSEDEERENENHLLVVPESRFDRDSGESEEAEEEVGEGTPQSS 375
Query: 138 TLS 140
L+
Sbjct: 376 ALT 378
Score = 40.4 bits (93), Expect = 0.004
Identities = 29/113 (25%), Positives = 55/113 (48%), Gaps = 12/113 (10%)
Query: 21 GAQLIHADKLGEK-----VEDSTMPIRRTVNSTRETPPKSKLAEGEEEKPEPDISSEESV 75
G + + +K+ E+ ++D + R+T ++ + +E EEE+ E + EE
Sbjct: 237 GRKPVKEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEE---EEEG 293
Query: 76 STVEEQENETPPATSSEAEQPKGEPENEEKEENKSSEETKKDEKDQSKEKEKK 128
ST EE E E E E+ + N E+ +S+EE ++E + +E+E +
Sbjct: 294 STSEESEEE----EEEEEEEEEETGSNSEEASEQSAEEVSEEEMSEDEERENE 342
Score = 35.0 bits (79), Expect = 0.18
Identities = 24/101 (23%), Positives = 44/101 (43%)
Query: 28 DKLGEKVEDSTMPIRRTVNSTRETPPKSKLAEGEEEKPEPDISSEESVSTVEEQENETPP 87
+K K ++ I+R NS + L EGE +I+ S E+ +
Sbjct: 19 EKKRRKEQEEKAEIKRLKNSDDRDSKRDSLEEGELRDHCMEITIRNSPYRREDSMEDRGE 78
Query: 88 ATSSEAEQPKGEPENEEKEENKSSEETKKDEKDQSKEKEKK 128
S A +P + +EK ++ E+ K+ + + KEKE++
Sbjct: 79 EDDSLAIKPPQQMSRKEKVHHRKDEKRKEKKHARVKEKERE 119
Score = 31.6 bits (70), Expect = 2.0
Identities = 23/94 (24%), Positives = 45/94 (47%), Gaps = 9/94 (9%)
Query: 35 EDSTMPIRRTVNSTRETPPKSKLAEGEEEKPEPDISSEESVSTVEEQENETPPATSSEAE 94
ED ++ I+ +R K K+ ++EK + E+ + V+E+E E E
Sbjct: 79 EDDSLAIKPPQQMSR----KEKVHHRKDEKRK-----EKKHARVKEKEREHERRKRHREE 129
Query: 95 QPKGEPENEEKEENKSSEETKKDEKDQSKEKEKK 128
Q K E E ++ + + E + E+D+ ++ E+K
Sbjct: 130 QDKARREWERQKRREMAREHSRRERDRLEQLERK 163
>gi|16332370 cell division cycle 2-like 1 (PITSLRE proteins) isoform
8 [Homo sapiens]
Length = 780
Score = 50.1 bits (118), Expect = 5e-06
Identities = 28/108 (25%), Positives = 53/108 (49%), Gaps = 5/108 (4%)
Query: 52 PPKSKLAEGEEEKPEPDISSEE-----SVSTVEEQENETPPATSSEAEQPKGEPENEEKE 106
PP+ + G+ KP + EE + + + E +T A SS AE G E EE+E
Sbjct: 236 PPRERFELGDGRKPVKEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEE 295
Query: 107 ENKSSEETKKDEKDQSKEKEKKVKKTIPSWATLSASQLARAQKQTPMA 154
E + E + +E ++ +E+E++ ++ S + ++ Q A + M+
Sbjct: 296 EEEEEEGSTSEESEEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEMS 343
Score = 44.3 bits (103), Expect = 3e-04
Identities = 31/123 (25%), Positives = 55/123 (44%), Gaps = 14/123 (11%)
Query: 32 EKVEDSTMPIRRTVNSTRETPPKSKLAEGEEEKPEPDISSEESVSTVEEQENETPPATSS 91
+ + DS +S+ E+ S+ E EEE+ E + S+ E EE+E E T S
Sbjct: 265 QDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGS 324
Query: 92 EAEQPKGEPENEEKEENKSSEETKKDE--------------KDQSKEKEKKVKKTIPSWA 137
+E+ + E EE S +E +++E +S+E E++V + P +
Sbjct: 325 NSEEASEQSAEEVSEEEMSEDEERENENHLLVVPESRFDRDSGESEEAEEEVGEGTPQSS 384
Query: 138 TLS 140
L+
Sbjct: 385 ALT 387
Score = 40.4 bits (93), Expect = 0.004
Identities = 29/113 (25%), Positives = 55/113 (48%), Gaps = 12/113 (10%)
Query: 21 GAQLIHADKLGEK-----VEDSTMPIRRTVNSTRETPPKSKLAEGEEEKPEPDISSEESV 75
G + + +K+ E+ ++D + R+T ++ + +E EEE+ E + EE
Sbjct: 246 GRKPVKEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEE---EEEG 302
Query: 76 STVEEQENETPPATSSEAEQPKGEPENEEKEENKSSEETKKDEKDQSKEKEKK 128
ST EE E E E E+ + N E+ +S+EE ++E + +E+E +
Sbjct: 303 STSEESEEE----EEEEEEEEEETGSNSEEASEQSAEEVSEEEMSEDEERENE 351
Score = 35.0 bits (79), Expect = 0.18
Identities = 24/101 (23%), Positives = 44/101 (43%)
Query: 28 DKLGEKVEDSTMPIRRTVNSTRETPPKSKLAEGEEEKPEPDISSEESVSTVEEQENETPP 87
+K K ++ I+R NS + L EGE +I+ S E+ +
Sbjct: 19 EKKRRKEQEEKAEIKRLKNSDDRDSKRDSLEEGELRDHCMEITIRNSPYRREDSMEDRGE 78
Query: 88 ATSSEAEQPKGEPENEEKEENKSSEETKKDEKDQSKEKEKK 128
S A +P + +EK ++ E+ K+ + + KEKE++
Sbjct: 79 EDDSLAIKPPQQMSRKEKVHHRKDEKRKEKKHARVKEKERE 119
>gi|16332364 cell division cycle 2-like 1 (PITSLRE proteins) isoform
5 [Homo sapiens]
Length = 748
Score = 50.1 bits (118), Expect = 5e-06
Identities = 28/108 (25%), Positives = 53/108 (49%), Gaps = 5/108 (4%)
Query: 52 PPKSKLAEGEEEKPEPDISSEE-----SVSTVEEQENETPPATSSEAEQPKGEPENEEKE 106
PP+ + G+ KP + EE + + + E +T A SS AE G E EE+E
Sbjct: 204 PPRERFELGDGRKPVKEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEE 263
Query: 107 ENKSSEETKKDEKDQSKEKEKKVKKTIPSWATLSASQLARAQKQTPMA 154
E + E + +E ++ +E+E++ ++ S + ++ Q A + M+
Sbjct: 264 EEEEEEGSTSEESEEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEMS 311
Score = 44.3 bits (103), Expect = 3e-04
Identities = 31/123 (25%), Positives = 55/123 (44%), Gaps = 14/123 (11%)
Query: 32 EKVEDSTMPIRRTVNSTRETPPKSKLAEGEEEKPEPDISSEESVSTVEEQENETPPATSS 91
+ + DS +S+ E+ S+ E EEE+ E + S+ E EE+E E T S
Sbjct: 233 QDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGS 292
Query: 92 EAEQPKGEPENEEKEENKSSEETKKDE--------------KDQSKEKEKKVKKTIPSWA 137
+E+ + E EE S +E +++E +S+E E++V + P +
Sbjct: 293 NSEEASEQSAEEVSEEEMSEDEERENENHLLVVPESRFDRDSGESEEAEEEVGEGTPQSS 352
Query: 138 TLS 140
L+
Sbjct: 353 ALT 355
Score = 40.4 bits (93), Expect = 0.004
Identities = 29/113 (25%), Positives = 55/113 (48%), Gaps = 12/113 (10%)
Query: 21 GAQLIHADKLGEK-----VEDSTMPIRRTVNSTRETPPKSKLAEGEEEKPEPDISSEESV 75
G + + +K+ E+ ++D + R+T ++ + +E EEE+ E + EE
Sbjct: 214 GRKPVKEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEE---EEEG 270
Query: 76 STVEEQENETPPATSSEAEQPKGEPENEEKEENKSSEETKKDEKDQSKEKEKK 128
ST EE E E E E+ + N E+ +S+EE ++E + +E+E +
Sbjct: 271 STSEESEEE----EEEEEEEEEETGSNSEEASEQSAEEVSEEEMSEDEERENE 319
Score = 31.2 bits (69), Expect = 2.6
Identities = 23/96 (23%), Positives = 43/96 (44%), Gaps = 2/96 (2%)
Query: 35 EDSTMPIRRTVNSTRETPPKSKLAEGEEEKPEPDISSEESV--STVEEQENETPPATSSE 92
ED ++ I+ +R+ + E +EK S E + V+E+E E
Sbjct: 45 EDDSLAIKPPQQMSRKEKVHHRKDEKRKEKRRHRSHSAEGGKHARVKEKEREHERRKRHR 104
Query: 93 AEQPKGEPENEEKEENKSSEETKKDEKDQSKEKEKK 128
EQ K E E ++ + + E + E+D+ ++ E+K
Sbjct: 105 EEQDKARREWERQKRREMAREHSRRERDRLEQLERK 140
>gi|16332362 cell division cycle 2-like 1 (PITSLRE proteins) isoform
4 [Homo sapiens]
Length = 737
Score = 50.1 bits (118), Expect = 5e-06
Identities = 28/108 (25%), Positives = 53/108 (49%), Gaps = 5/108 (4%)
Query: 52 PPKSKLAEGEEEKPEPDISSEE-----SVSTVEEQENETPPATSSEAEQPKGEPENEEKE 106
PP+ + G+ KP + EE + + + E +T A SS AE G E EE+E
Sbjct: 193 PPRERFELGDGRKPVKEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEE 252
Query: 107 ENKSSEETKKDEKDQSKEKEKKVKKTIPSWATLSASQLARAQKQTPMA 154
E + E + +E ++ +E+E++ ++ S + ++ Q A + M+
Sbjct: 253 EEEEEEGSTSEESEEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEMS 300
Score = 44.3 bits (103), Expect = 3e-04
Identities = 31/123 (25%), Positives = 55/123 (44%), Gaps = 14/123 (11%)
Query: 32 EKVEDSTMPIRRTVNSTRETPPKSKLAEGEEEKPEPDISSEESVSTVEEQENETPPATSS 91
+ + DS +S+ E+ S+ E EEE+ E + S+ E EE+E E T S
Sbjct: 222 QDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGS 281
Query: 92 EAEQPKGEPENEEKEENKSSEETKKDE--------------KDQSKEKEKKVKKTIPSWA 137
+E+ + E EE S +E +++E +S+E E++V + P +
Sbjct: 282 NSEEASEQSAEEVSEEEMSEDEERENENHLLVVPESRFDRDSGESEEAEEEVGEGTPQSS 341
Query: 138 TLS 140
L+
Sbjct: 342 ALT 344
Score = 40.4 bits (93), Expect = 0.004
Identities = 29/113 (25%), Positives = 55/113 (48%), Gaps = 12/113 (10%)
Query: 21 GAQLIHADKLGEK-----VEDSTMPIRRTVNSTRETPPKSKLAEGEEEKPEPDISSEESV 75
G + + +K+ E+ ++D + R+T ++ + +E EEE+ E + EE
Sbjct: 203 GRKPVKEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEE---EEEG 259
Query: 76 STVEEQENETPPATSSEAEQPKGEPENEEKEENKSSEETKKDEKDQSKEKEKK 128
ST EE E E E E+ + N E+ +S+EE ++E + +E+E +
Sbjct: 260 STSEESEEE----EEEEEEEEEETGSNSEEASEQSAEEVSEEEMSEDEERENE 308
Score = 31.6 bits (70), Expect = 2.0
Identities = 23/94 (24%), Positives = 45/94 (47%), Gaps = 9/94 (9%)
Query: 35 EDSTMPIRRTVNSTRETPPKSKLAEGEEEKPEPDISSEESVSTVEEQENETPPATSSEAE 94
ED ++ I+ +R K K+ ++EK + E+ + V+E+E E E
Sbjct: 45 EDDSLAIKPPQQMSR----KEKVHHRKDEKRK-----EKKHARVKEKEREHERRKRHREE 95
Query: 95 QPKGEPENEEKEENKSSEETKKDEKDQSKEKEKK 128
Q K E E ++ + + E + E+D+ ++ E+K
Sbjct: 96 QDKARREWERQKRREMAREHSRRERDRLEQLERK 129
Score = 29.3 bits (64), Expect = 9.8
Identities = 18/75 (24%), Positives = 34/75 (45%)
Query: 54 KSKLAEGEEEKPEPDISSEESVSTVEEQENETPPATSSEAEQPKGEPENEEKEENKSSEE 113
+ L EGE +I+ S E+ + S A +P + +EK ++ E+
Sbjct: 11 RDSLEEGELRDHRMEITIRNSPYRREDSMEDRGEEDDSLAIKPPQQMSRKEKVHHRKDEK 70
Query: 114 TKKDEKDQSKEKEKK 128
K+ + + KEKE++
Sbjct: 71 RKEKKHARVKEKERE 85
>gi|16332358 cell division cycle 2-like 1 (PITSLRE proteins) isoform
2 [Homo sapiens]
Length = 782
Score = 50.1 bits (118), Expect = 5e-06
Identities = 28/108 (25%), Positives = 53/108 (49%), Gaps = 5/108 (4%)
Query: 52 PPKSKLAEGEEEKPEPDISSEE-----SVSTVEEQENETPPATSSEAEQPKGEPENEEKE 106
PP+ + G+ KP + EE + + + E +T A SS AE G E EE+E
Sbjct: 238 PPRERFELGDGRKPVKEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEE 297
Query: 107 ENKSSEETKKDEKDQSKEKEKKVKKTIPSWATLSASQLARAQKQTPMA 154
E + E + +E ++ +E+E++ ++ S + ++ Q A + M+
Sbjct: 298 EEEEEEGSTSEESEEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEMS 345
Score = 44.3 bits (103), Expect = 3e-04
Identities = 31/123 (25%), Positives = 55/123 (44%), Gaps = 14/123 (11%)
Query: 32 EKVEDSTMPIRRTVNSTRETPPKSKLAEGEEEKPEPDISSEESVSTVEEQENETPPATSS 91
+ + DS +S+ E+ S+ E EEE+ E + S+ E EE+E E T S
Sbjct: 267 QDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGS 326
Query: 92 EAEQPKGEPENEEKEENKSSEETKKDE--------------KDQSKEKEKKVKKTIPSWA 137
+E+ + E EE S +E +++E +S+E E++V + P +
Sbjct: 327 NSEEASEQSAEEVSEEEMSEDEERENENHLLVVPESRFDRDSGESEEAEEEVGEGTPQSS 386
Query: 138 TLS 140
L+
Sbjct: 387 ALT 389
Score = 40.4 bits (93), Expect = 0.004
Identities = 29/113 (25%), Positives = 55/113 (48%), Gaps = 12/113 (10%)
Query: 21 GAQLIHADKLGEK-----VEDSTMPIRRTVNSTRETPPKSKLAEGEEEKPEPDISSEESV 75
G + + +K+ E+ ++D + R+T ++ + +E EEE+ E + EE
Sbjct: 248 GRKPVKEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEE---EEEG 304
Query: 76 STVEEQENETPPATSSEAEQPKGEPENEEKEENKSSEETKKDEKDQSKEKEKK 128
ST EE E E E E+ + N E+ +S+EE ++E + +E+E +
Sbjct: 305 STSEESEEE----EEEEEEEEEETGSNSEEASEQSAEEVSEEEMSEDEERENE 353
Score = 32.3 bits (72), Expect = 1.2
Identities = 22/99 (22%), Positives = 40/99 (40%)
Query: 28 DKLGEKVEDSTMPIRRTVNSTRETPPKSKLAEGEEEKPEPDISSEESVSTVEEQENETPP 87
+K K ++ I+R NS + L EGE +I+ S E+ +
Sbjct: 19 EKKRRKEQEEKAEIKRLKNSDDRDSKRDSLEEGELRDHRMEITIRNSPYRREDSMEDRGE 78
Query: 88 ATSSEAEQPKGEPENEEKEENKSSEETKKDEKDQSKEKE 126
S A +P + +EK ++ E+ K+ + +S E
Sbjct: 79 EDDSLAIKPPQQMSRKEKVHHRKDEKRKEKRRHRSHSAE 117
Score = 31.2 bits (69), Expect = 2.6
Identities = 23/96 (23%), Positives = 43/96 (44%), Gaps = 2/96 (2%)
Query: 35 EDSTMPIRRTVNSTRETPPKSKLAEGEEEKPEPDISSEESV--STVEEQENETPPATSSE 92
ED ++ I+ +R+ + E +EK S E + V+E+E E
Sbjct: 79 EDDSLAIKPPQQMSRKEKVHHRKDEKRKEKRRHRSHSAEGGKHARVKEKEREHERRKRHR 138
Query: 93 AEQPKGEPENEEKEENKSSEETKKDEKDQSKEKEKK 128
EQ K E E ++ + + E + E+D+ ++ E+K
Sbjct: 139 EEQDKARREWERQKRREMAREHSRRERDRLEQLERK 174
>gi|20544168 histone cluster 1, H1t [Homo sapiens]
Length = 207
Score = 50.1 bits (118), Expect = 5e-06
Identities = 27/93 (29%), Positives = 54/93 (58%), Gaps = 2/93 (2%)
Query: 157 PRPKMDAILTEAIKACFQKSGASVVAIRKYIIHKYPSLELERRGYLLKQALKRELNRGVI 216
P + ++TEA+ ++ G S+VA++K + ++E+ +K +LK +N+G++
Sbjct: 40 PNLSVSKLITEALSVSQERVGMSLVALKKALAAA--GYDVEKNNSRIKLSLKSLVNKGIL 97
Query: 217 KQVKGKGASGSFVVVQKSRKTPQKSRNRKNRSS 249
Q +G GASGSF + +K +S+ +K+ S+
Sbjct: 98 VQTRGTGASGSFKLSKKVIPKSTRSKAKKSVSA 130
Score = 32.0 bits (71), Expect = 1.5
Identities = 30/109 (27%), Positives = 48/109 (44%), Gaps = 4/109 (3%)
Query: 224 ASGSFVVVQKSRKTPQKSRNRKNRS--SAVDPEPQVKLEDVLPLAFTRLCEPKEASYSLI 281
A+ + V K P K R RK SA P + + ++ A + E S +
Sbjct: 7 AASASAGVAAMEKLPTKKRGRKPAGLISASRKVPNLSVSKLITEALSVSQERVGMSLVAL 66
Query: 282 RKYVSQYYPKLRVDIRPQLLKNALQRAVERGQLEQITGKGASGTFQLKK 330
+K ++ V+ +K +L+ V +G L Q G GASG+F+L K
Sbjct: 67 KKALAA--AGYDVEKNNSRIKLSLKSLVNKGILVQTRGTGASGSFKLSK 113
Score = 31.6 bits (70), Expect = 2.0
Identities = 42/181 (23%), Positives = 65/181 (35%), Gaps = 11/181 (6%)
Query: 319 GKGASGTFQLKKSGEKP--LLGGSL------MEYAILSAIAAMNEPKTCSTTALKKYVLE 370
G A KK G KP L+ S + I A++ E S ALKK +
Sbjct: 13 GVAAMEKLPTKKRGRKPAGLISASRKVPNLSVSKLITEALSVSQERVGMSLVALKKALAA 72
Query: 371 NHPGTNSNYQMHLLKKTLQKCEKNGWMEQISGKGFSGTFQLCFPYYPSPGVLFPKKEPD- 429
N +K +L+ G + Q G G SG+F+L P KK
Sbjct: 73 AGYDVEKNNSR--IKLSLKSLVNKGILVQTRGTGASGSFKLSKKVIPKSTRSKAKKSVSA 130
Query: 430 DSRDEDEDEDESSEEDSEDEEPPPKRRLQKKTPAKSPGKAASVKQRGSKPAPKVSAAQRG 489
++ D S + ++ + K R +S KA K + + +P + A +
Sbjct: 131 KTKKLVLSRDSKSPKTAKTNKRAKKPRATTPKTVRSGRKAKGAKGKQQQKSPVKARASKS 190
Query: 490 K 490
K
Sbjct: 191 K 191
Score = 30.0 bits (66), Expect = 5.8
Identities = 21/75 (28%), Positives = 32/75 (42%), Gaps = 1/75 (1%)
Query: 473 KQRGSKPAPKVSAAQRGKARPLPKKAPPKAKTPAKKTRPSSTVIKKPSGGSSKKPATSAR 532
K SK VSA + K+P AKT + +P +T K G K A +
Sbjct: 118 KSTRSKAKKSVSAKTKKLVLSRDSKSPKTAKTNKRAKKPRATTPKTVRSGRKAKGA-KGK 176
Query: 533 KEVKLPGKGKSTMKK 547
++ K P K +++ K
Sbjct: 177 QQQKSPVKARASKSK 191
>gi|10835063 nucleophosmin 1 isoform 1 [Homo sapiens]
Length = 294
Score = 49.3 bits (116), Expect = 9e-06
Identities = 37/111 (33%), Positives = 53/111 (47%), Gaps = 9/111 (8%)
Query: 427 EPDDSRDEDEDEDESSEEDSEDEEPPPKRRLQKKTPAKSPGKAASVKQRGSKPAPKVSAA 486
+ DD D+DED+D+ +D E EE P ++ + TPAK+ K+ Q G P S+
Sbjct: 165 DDDDEEDDDEDDDDDDFDDEEAEEKAPVKKSIRDTPAKNAQKS---NQNGKDSKP--SST 219
Query: 487 QRGKARPLPKKAPPKAKTPAKKTRPSSTV-IKKPSGGSSKKPATSARKEVK 536
R K + KK + KTP PSS IK S +K + + E K
Sbjct: 220 PRSKGQESFKK---QEKTPKTPKGPSSVEDIKAKMQASIEKGGSLPKVEAK 267
Score = 40.0 bits (92), Expect = 0.006
Identities = 26/104 (25%), Positives = 47/104 (45%), Gaps = 5/104 (4%)
Query: 62 EEKPEPDISSEESVSTVEEQENETPPATSSEAEQPK-----GEPENEEKEENKSSEETKK 116
EE E + EE V + + P S+ Q K E ++++ EE+ ++
Sbjct: 120 EEDAESEDEEEEDVKLLSISGKRSAPGGGSKVPQKKVKLAADEDDDDDDEEDDDEDDDDD 179
Query: 117 DEKDQSKEKEKKVKKTIPSWATLSASQLARAQKQTPMASSPRPK 160
D D+ E++ VKK+I +A + + K + +S+PR K
Sbjct: 180 DFDDEEAEEKAPVKKSIRDTPAKNAQKSNQNGKDSKPSSTPRSK 223
Score = 35.0 bits (79), Expect = 0.18
Identities = 37/179 (20%), Positives = 70/179 (39%), Gaps = 21/179 (11%)
Query: 19 IVGAQLIHADKLGEKVEDSTMPIRRTVNSTRETPP---------KSKLAEGEEEKP---E 66
I G L+ ++ E ++ ++ S + + P K KLA E++ E
Sbjct: 111 ISGQHLVAVEEDAESEDEEEEDVKLLSISGKRSAPGGGSKVPQKKVKLAADEDDDDDDEE 170
Query: 67 PDISSEESVSTVEEQENETPPATSSEAEQP--KGEPENEEKEENK--SSEETKKDEKDQS 122
D ++ +E+ E P S + P + N+ +++K S+ +K E +
Sbjct: 171 DDDEDDDDDDFDDEEAEEKAPVKKSIRDTPAKNAQKSNQNGKDSKPSSTPRSKGQESFKK 230
Query: 123 KEKEKKVKKTIPSWATLSASQLARAQKQTPMASSPRPKMDAILTEAIKACFQKSGASVV 181
+EK K K S + A A +K PK++A +K CF+ + +
Sbjct: 231 QEKTPKTPKGPSSVEDIKAKMQASIEK-----GGSLPKVEAKFINYVKNCFRMTDQEAI 284
>gi|4885379 histone cluster 1, H1e [Homo sapiens]
Length = 219
Score = 49.3 bits (116), Expect = 9e-06
Identities = 26/87 (29%), Positives = 50/87 (57%), Gaps = 2/87 (2%)
Query: 159 PKMDAILTEAIKACFQKSGASVVAIRKYIIHKYPSLELERRGYLLKQALKRELNRGVIKQ 218
P + ++T+A+ A ++SG S+ A++K + ++E+ +K LK +++G + Q
Sbjct: 38 PPVSELITKAVAASKERSGVSLAALKKALAAA--GYDVEKNNSRIKLGLKSLVSKGTLVQ 95
Query: 219 VKGKGASGSFVVVQKSRKTPQKSRNRK 245
KG GASGSF + +K+ K + +K
Sbjct: 96 TKGTGASGSFKLNKKAASGEAKPKAKK 122
Score = 48.5 bits (114), Expect = 2e-05
Identities = 52/189 (27%), Positives = 75/189 (39%), Gaps = 15/189 (7%)
Query: 346 ILSAIAAMNEPKTCSTTALKKYVLENHPGTNSNYQMHLLKKTLQKCEKNGWMEQISGKGF 405
I A+AA E S ALKK + N +K L+ G + Q G G
Sbjct: 44 ITKAVAASKERSGVSLAALKKALAAAGYDVEKNNSR--IKLGLKSLVSKGTLVQTKGTGA 101
Query: 406 SGTFQLCFPYYPSPGVLFPKKEPDDSRDEDEDEDESSEEDSEDEEPPPKRRLQKKTPAKS 465
SG+F+L + G PK + + + + + PK+ KKTP K+
Sbjct: 102 SGSFKL--NKKAASGEAKPKAKKAGAAKAKKPAGAAKKPKKATGAATPKKSA-KKTPKKA 158
Query: 466 PGKAASVKQRGSKPAPKVSAAQRGKARPLPKKAPPKAKTPAKKTRPSSTVIK--KPSGGS 523
AA+ + +K K AA+ PKKAP K+ AK +P + K KP
Sbjct: 159 KKPAAAAGAKKAKSPKKAKAAK-------PKKAP-KSPAKAKAVKPKAAKPKTAKPKAAK 210
Query: 524 SKKPATSAR 532
KK A +
Sbjct: 211 PKKAAAKKK 219
Score = 36.2 bits (82), Expect = 0.081
Identities = 29/103 (28%), Positives = 48/103 (46%), Gaps = 5/103 (4%)
Query: 234 SRKTPQKSRNRKNRSSAVDPEPQVKLEDVLPLAFTRLCEPKEASYSLIRKYVSQYYPKLR 293
+ KTP K + RK+ +A + +++ A E S + ++K ++
Sbjct: 15 AEKTPVKKKARKSAGAAKRKASGPPVSELITKAVAASKERSGVSLAALKKALAA--AGYD 72
Query: 294 VDIRPQLLKNALQRAVERGQLEQITGKGASGTFQLKK---SGE 333
V+ +K L+ V +G L Q G GASG+F+L K SGE
Sbjct: 73 VEKNNSRIKLGLKSLVSKGTLVQTKGTGASGSFKLNKKAASGE 115
>gi|4885375 histone cluster 1, H1c [Homo sapiens]
Length = 213
Score = 49.3 bits (116), Expect = 9e-06
Identities = 29/95 (30%), Positives = 54/95 (56%), Gaps = 3/95 (3%)
Query: 151 TPMASSPRPKMDAILTEAIKACFQKSGASVVAIRKYIIHKYPSLELERRGYLLKQALKRE 210
TP +S P + ++T+A+ A ++SG S+ A++K + ++E+ +K LK
Sbjct: 31 TPRKASG-PPVSELITKAVAASKERSGVSLAALKKALAAA--GYDVEKNNSRIKLGLKSL 87
Query: 211 LNRGVIKQVKGKGASGSFVVVQKSRKTPQKSRNRK 245
+++G + Q KG GASGSF + +K+ K + +K
Sbjct: 88 VSKGTLVQTKGTGASGSFKLNKKAASGEAKPKVKK 122
Score = 46.2 bits (108), Expect = 8e-05
Identities = 58/226 (25%), Positives = 79/226 (34%), Gaps = 45/226 (19%)
Query: 329 KKSGEKPL-LGGSLMEYAILSAIAAMNEPKTCSTTALKKYVLENHPGTNSNYQMHLLKKT 387
KK+G P G + I A+AA E S ALKK + N +K
Sbjct: 26 KKAGGTPRKASGPPVSELITKAVAASKERSGVSLAALKKALAAAGYDVEKNNSR--IKLG 83
Query: 388 LQKCEKNGWMEQISGKGFSGTFQLCFPYYPSPGVLFPKKEPDDSRDEDEDEDESSEEDSE 447
L+ G + Q G G SG+F+L +++ +
Sbjct: 84 LKSLVSKGTLVQTKGTGASGSFKL------------------------------NKKAAS 113
Query: 448 DEEPPPKRRLQKKTPAKSPGKAASVKQRGSKPAPKVSAAQRGKARPLPKKAPPKAKTPAK 507
E P ++ P K G A K+ PK SA KK P KAK PA
Sbjct: 114 GEAKPKVKKAGGTKPKKPVGAAKKPKKAAGGATPKKSA----------KKTPKKAKKPAA 163
Query: 508 KTRPSSTVIKKPSGGSSKKPATSARKEVKLPGKGKSTMKKSFRVKK 553
T + V K P KP +A+ K K K+ K + KK
Sbjct: 164 AT-VTKKVAKSPKKAKVAKPKKAAKSAAKAV-KPKAAKPKVVKPKK 207
Score = 32.7 bits (73), Expect = 0.89
Identities = 37/133 (27%), Positives = 55/133 (41%), Gaps = 12/133 (9%)
Query: 301 LKNALQRAVERGQLEQITGKGASGTFQLKK---SGE-KPLL---GGSLMEYAILSAIAAM 353
+K L+ V +G L Q G GASG+F+L K SGE KP + GG+ + + A
Sbjct: 80 IKLGLKSLVSKGTLVQTKGTGASGSFKLNKKAASGEAKPKVKKAGGTKPK----KPVGAA 135
Query: 354 NEPKTCSTTALKKYVLENHPGTNSNYQMHLLKKTLQKCEKNGWMEQISGKGFSGTFQLCF 413
+PK + A K + P + K + K K + + K +
Sbjct: 136 KKPKKAAGGATPKKSAKKTPKKAKKPAAATVTKKVAKSPKKAKVAK-PKKAAKSAAKAVK 194
Query: 414 PYYPSPGVLFPKK 426
P P V+ PKK
Sbjct: 195 PKAAKPKVVKPKK 207
>gi|4885377 histone cluster 1, H1d [Homo sapiens]
Length = 221
Score = 48.9 bits (115), Expect = 1e-05
Identities = 26/87 (29%), Positives = 50/87 (57%), Gaps = 2/87 (2%)
Query: 159 PKMDAILTEAIKACFQKSGASVVAIRKYIIHKYPSLELERRGYLLKQALKRELNRGVIKQ 218
P + ++T+A+ A ++SG S+ A++K + ++E+ +K LK +++G + Q
Sbjct: 39 PPVSELITKAVAASKERSGVSLAALKKALAAA--GYDVEKNNSRIKLGLKSLVSKGTLVQ 96
Query: 219 VKGKGASGSFVVVQKSRKTPQKSRNRK 245
KG GASGSF + +K+ K + +K
Sbjct: 97 TKGTGASGSFKLNKKAASGEGKPKAKK 123
Score = 47.4 bits (111), Expect = 3e-05
Identities = 53/199 (26%), Positives = 79/199 (39%), Gaps = 21/199 (10%)
Query: 329 KKSGE---KPLLGGSLMEYAILSAIAAMNEPKTCSTTALKKYVLENHPGTNSNYQMHLLK 385
KK+G K G + I A+AA E S ALKK + N +K
Sbjct: 25 KKAGATAGKRKASGPPVSELITKAVAASKERSGVSLAALKKALAAAGYDVEKNNSR--IK 82
Query: 386 KTLQKCEKNGWMEQISGKGFSGTFQLCF--------PYYPSPGVLFPKKEPDDSRDEDED 437
L+ G + Q G G SG+F+L P G P+K ++ +
Sbjct: 83 LGLKSLVSKGTLVQTKGTGASGSFKLNKKAASGEGKPKAKKAGAAKPRKPAGAAKKPKKV 142
Query: 438 EDESSEEDSEDEEPPPKRRLQKKTPAKSPGKAASVKQRGSKPAPKVSAAQRGKAR-PLPK 496
++ + S + P ++++K A K A ++ P PK +A KA+ P PK
Sbjct: 143 AGAATPKKSIKKTP---KKVKKPATAAGTKKVAKSAKKVKTPQPKKAAKSPAKAKAPKPK 199
Query: 497 KAPPKAKTP----AKKTRP 511
A PK+ P AKK P
Sbjct: 200 AAKPKSGKPKVTKAKKAAP 218
Score = 30.4 bits (67), Expect = 4.4
Identities = 28/104 (26%), Positives = 49/104 (47%), Gaps = 6/104 (5%)
Query: 234 SRKTPQKSRNRKNRSSAVDPEPQ-VKLEDVLPLAFTRLCEPKEASYSLIRKYVSQYYPKL 292
+ KTP K + +K ++A + + +++ A E S + ++K ++
Sbjct: 15 AEKTPVKKKAKKAGATAGKRKASGPPVSELITKAVAASKERSGVSLAALKKALAA--AGY 72
Query: 293 RVDIRPQLLKNALQRAVERGQLEQITGKGASGTFQLKK---SGE 333
V+ +K L+ V +G L Q G GASG+F+L K SGE
Sbjct: 73 DVEKNNSRIKLGLKSLVSKGTLVQTKGTGASGSFKLNKKAASGE 116
>gi|4885381 histone cluster 1, H1b [Homo sapiens]
Length = 226
Score = 48.9 bits (115), Expect = 1e-05
Identities = 59/233 (25%), Positives = 91/233 (39%), Gaps = 16/233 (6%)
Query: 302 KNALQRAVERGQLEQITGKGASGTFQLKKSGEKPLLGGSLMEYAILSAIAAMNEPKTCST 361
+ A VE+ ++ K A+G K+ P + I A+AA E S
Sbjct: 8 ETATPAPVEKSPAKKKATKKAAGAGAAKRKATGPPVSE-----LITKAVAASKERNGLSL 62
Query: 362 TALKKYVLENHPGTNSNYQMHLLKKTLQKCEKNGWMEQISGKGFSGTFQLCFPYYPSPGV 421
ALKK + N +K L+ G + Q G G SG+F+L + G
Sbjct: 63 AALKKALAAGGYDVEKNNSR--IKLGLKSLVSKGTLVQTKGTGASGSFKL--NKKAASGE 118
Query: 422 LFPKKEPDDSRDEDEDEDESSEEDSEDEEPPPKRRLQKKTP--AKSPGKAASVKQRGSKP 479
PK + + + + + + ++ ++ KKTP AK P AA VK+ P
Sbjct: 119 AKPKAKKAGAA---KAKKPAGATPKKAKKAAGAKKAVKKTPKKAKKPA-AAGVKKVAKSP 174
Query: 480 APKVSAAQRGKARPLPKKAPPKAKTPAKKTRPSSTVIKKPSGGSSKKPATSAR 532
+AA+ KA P K P K A K + + KP +KK A +
Sbjct: 175 KKAKAAAKPKKATKSPAK-PKAVKPKAAKPKAAKPKAAKPKAAKAKKAAAKKK 226
Score = 47.4 bits (111), Expect = 3e-05
Identities = 25/87 (28%), Positives = 50/87 (57%), Gaps = 2/87 (2%)
Query: 159 PKMDAILTEAIKACFQKSGASVVAIRKYIIHKYPSLELERRGYLLKQALKRELNRGVIKQ 218
P + ++T+A+ A +++G S+ A++K + ++E+ +K LK +++G + Q
Sbjct: 41 PPVSELITKAVAASKERNGLSLAALKKALAAG--GYDVEKNNSRIKLGLKSLVSKGTLVQ 98
Query: 219 VKGKGASGSFVVVQKSRKTPQKSRNRK 245
KG GASGSF + +K+ K + +K
Sbjct: 99 TKGTGASGSFKLNKKAASGEAKPKAKK 125
Score = 37.4 bits (85), Expect = 0.036
Identities = 32/95 (33%), Positives = 45/95 (47%), Gaps = 13/95 (13%)
Query: 468 KAASVKQRGSKPAPKVSAAQRGK--ARPLPKKAPPKA-------KTPAKKTRPSSTVIKK 518
KAAS + +KP K + A + K A PKKA A KTP K +P++ +KK
Sbjct: 113 KAASGE---AKPKAKKAGAAKAKKPAGATPKKAKKAAGAKKAVKKTPKKAKKPAAAGVKK 169
Query: 519 PSGGSSK-KPATSARKEVKLPGKGKSTMKKSFRVK 552
+ K K A +K K P K K+ K+ + K
Sbjct: 170 VAKSPKKAKAAAKPKKATKSPAKPKAVKPKAAKPK 204
Score = 30.0 bits (66), Expect = 5.8
Identities = 17/36 (47%), Positives = 22/36 (61%), Gaps = 3/36 (8%)
Query: 301 LKNALQRAVERGQLEQITGKGASGTFQLKK---SGE 333
+K L+ V +G L Q G GASG+F+L K SGE
Sbjct: 83 IKLGLKSLVSKGTLVQTKGTGASGSFKLNKKAASGE 118
>gi|55956788 nucleolin [Homo sapiens]
Length = 710
Score = 48.5 bits (114), Expect = 2e-05
Identities = 43/119 (36%), Positives = 54/119 (45%), Gaps = 17/119 (14%)
Query: 424 PKKEPDDSRDEDEDEDESSEEDSEDEEPPPKRRLQKKTPAKSPGKAASVKQRGSKPAPKV 483
PK+ +DS DE+ EDE E+DS EE ++ KK A S K P KV
Sbjct: 21 PKEVEEDSEDEEMSEDE--EDDSSGEEVVIPQKKGKKAAATSAKKVV------VSPTKKV 72
Query: 484 SAAQRGKARPLP--KKAPPKAKTPAKKTRPSSTVIKKPSGGSSKKPATSARKEVKLPGK 540
+ A K + KKA A TPAKKT + + P KK AT + V PGK
Sbjct: 73 AVATPAKKAAVTPGKKA---AATPAKKTVTPAKAVTTP----GKKGATPGKALVATPGK 124
Score = 40.4 bits (93), Expect = 0.004
Identities = 25/88 (28%), Positives = 41/88 (46%), Gaps = 9/88 (10%)
Query: 55 SKLAEGEEEKPEPDISSEESVSTVEEQENETPPATSSEAEQPKGEPENEEKEENKSSEET 114
+K + +EE+ + EE +E E+E PA A E+E+ E+++ E+
Sbjct: 140 AKKEDSDEEEDDDSEEDEEDDEDEDEDEDEIEPAAMKAAAAAPAS-EDEDDEDDEDDEDD 198
Query: 115 KKDEKDQSKE--------KEKKVKKTIP 134
DE+D S+E K KK K +P
Sbjct: 199 DDDEEDDSEEEAMETTPAKGKKAAKVVP 226
Score = 39.7 bits (91), Expect = 0.007
Identities = 19/42 (45%), Positives = 26/42 (61%), Gaps = 1/42 (2%)
Query: 431 SRDEDEDEDESSEEDSEDEEPPPKRRLQKKTPAKSPGKAASV 472
S DED+++DE E+D +DEE + + TPAK KAA V
Sbjct: 184 SEDEDDEDDEDDEDDDDDEEDDSEEEAMETTPAKGK-KAAKV 224
Score = 39.3 bits (90), Expect = 0.010
Identities = 17/58 (29%), Positives = 30/58 (51%)
Query: 425 KKEPDDSRDEDEDEDESSEEDSEDEEPPPKRRLQKKTPAKSPGKAASVKQRGSKPAPK 482
++E D+ D+D+DED+ ++D +DEE + + A K KQ+ + A K
Sbjct: 238 EEEDDEDEDDDDDEDDEDDDDEDDEEEEEEEEEEPVKEAPGKRKKEMAKQKAAPEAKK 295
Score = 39.3 bits (90), Expect = 0.010
Identities = 20/59 (33%), Positives = 34/59 (57%), Gaps = 5/59 (8%)
Query: 426 KEPDDSRDEDEDEDESSEEDSEDEEPPPKRRL---QKKTPAKSPGKAASVKQR--GSKP 479
++ DD D+++D+DE EE+ E+EE P + +KK AK + KQ+ G++P
Sbjct: 245 EDDDDDEDDEDDDDEDDEEEEEEEEEEPVKEAPGKRKKEMAKQKAAPEAKKQKVEGTEP 303
Score = 38.1 bits (87), Expect = 0.021
Identities = 46/200 (23%), Positives = 80/200 (40%), Gaps = 34/200 (17%)
Query: 28 DKLGEKVEDSTMPIRRTVNSTRETPPKSKLAEGEEEKPEPDISSEESVSTVEEQENETPP 87
D+ ++ ED P + + P + ++E E D EE S EE+ ET P
Sbjct: 160 DEDEDEDEDEIEPA--AMKAAAAAPASEDEDDEDDEDDEDDDDDEEDDS--EEEAMETTP 215
Query: 88 ATSSEAEQ-----PKGEPENEEKEENKSSE-----------ETKKDEKDQSKEKEKKVKK 131
A +A + K E+E++EE+ E + + DE+++ +E+E+ VK+
Sbjct: 216 AKGKKAAKVVPVKAKNVAEDEDEEEDDEDEDDDDDEDDEDDDDEDDEEEEEEEEEEPVKE 275
Query: 132 TIPSWATLSASQLA--RAQKQTPMASSPRPKMDAI------------LTEAIKACFQKSG 177
A Q A A+KQ + P + L I F K+
Sbjct: 276 APGKRKKEMAKQKAAPEAKKQKVEGTEPTTAFNLFVGNLNFNKSAPELKTGISDVFAKND 335
Query: 178 ASVVAIRKYIIHKYPSLELE 197
+VV +R + K+ ++ E
Sbjct: 336 LAVVDVRIGMTRKFGYVDFE 355
Score = 35.0 bits (79), Expect = 0.18
Identities = 17/48 (35%), Positives = 26/48 (54%)
Query: 427 EPDDSRDEDEDEDESSEEDSEDEEPPPKRRLQKKTPAKSPGKAASVKQ 474
E D+ ++DED+D+ E+DSE+E KK P KA +V +
Sbjct: 187 EDDEDDEDDEDDDDDEEDDSEEEAMETTPAKGKKAAKVVPVKAKNVAE 234
Score = 34.7 bits (78), Expect = 0.23
Identities = 13/44 (29%), Positives = 26/44 (59%)
Query: 426 KEPDDSRDEDEDEDESSEEDSEDEEPPPKRRLQKKTPAKSPGKA 469
++ +D D+D+DE++ SEE++ + P ++ K P K+ A
Sbjct: 190 EDDEDDEDDDDDEEDDSEEEAMETTPAKGKKAAKVVPVKAKNVA 233
Score = 33.5 bits (75), Expect = 0.52
Identities = 12/26 (46%), Positives = 19/26 (73%)
Query: 426 KEPDDSRDEDEDEDESSEEDSEDEEP 451
+E DD +EDE++DE +ED ++ EP
Sbjct: 147 EEEDDDSEEDEEDDEDEDEDEDEIEP 172
Score = 32.0 bits (71), Expect = 1.5
Identities = 10/26 (38%), Positives = 19/26 (73%)
Query: 425 KKEPDDSRDEDEDEDESSEEDSEDEE 450
K++ D+ D+D +EDE +ED +++E
Sbjct: 142 KEDSDEEEDDDSEEDEEDDEDEDEDE 167
Score = 31.2 bits (69), Expect = 2.6
Identities = 12/42 (28%), Positives = 22/42 (52%)
Query: 425 KKEPDDSRDEDEDEDESSEEDSEDEEPPPKRRLQKKTPAKSP 466
KKE D ++D+ E++ +++ EDE+ K A +P
Sbjct: 141 KKEDSDEEEDDDSEEDEEDDEDEDEDEDEIEPAAMKAAAAAP 182
Score = 30.8 bits (68), Expect = 3.4
Identities = 15/35 (42%), Positives = 20/35 (57%), Gaps = 1/35 (2%)
Query: 417 PSPGVLFPKKEPDDSRDEDEDED-ESSEEDSEDEE 450
P+ G K + DE+ED+D E EED EDE+
Sbjct: 130 PAKGAKNGKNAKKEDSDEEEDDDSEEDEEDDEDED 164
Score = 30.4 bits (67), Expect = 4.4
Identities = 24/86 (27%), Positives = 40/86 (46%), Gaps = 5/86 (5%)
Query: 88 ATSSEAEQPKGEPENEEKEENKSSEETKKDEKDQSKEKEKKV--KKTIPSWATLSASQLA 145
A ++ + K P +E EE+ EE +DE+D S +E + KK + AT + +
Sbjct: 7 AGKNQGDPKKMAPPPKEVEEDSEDEEMSEDEEDDSSGEEVVIPQKKGKKAAATSAKKVVV 66
Query: 146 RAQKQTPMASSPRPKMDAILTEAIKA 171
K+ +A+ P A +T KA
Sbjct: 67 SPTKKVAVAT---PAKKAAVTPGKKA 89
>gi|197927454 DEK oncogene isoform 2 [Homo sapiens]
Length = 341
Score = 48.5 bits (114), Expect = 2e-05
Identities = 48/205 (23%), Positives = 87/205 (42%), Gaps = 22/205 (10%)
Query: 10 LVHPKALPLIVGAQLIHADKL---GEKVEDSTMPIRRTVNSTRETPPKSKLAEGEEEKPE 66
L+HPK G L + K G K E ++ + R T+ S + +E++ +
Sbjct: 149 LMHPKPS----GKPLPKSKKTCSKGSKKERNSSGMARKAKRTKCPEILSDESSSDEDEKK 204
Query: 67 PDISSEESVSTVEEQENETPPATSSEAEQPKGEPENEEKEENKSSEETKKDEKDQSKEKE 126
+ EES +++ E PP +++ E+PK + ++ K+ KS+ KK + +K+ +
Sbjct: 205 ---NKEESSDDEDKESEEEPPKKTAKREKPKQKATSKSKKSVKSA-NVKKADSSTTKKNQ 260
Query: 127 KKVKKTIPSWATLSASQLARAQKQTPMASSPRPKMDAILTEAIKACFQKSGASVVAIR-- 184
KK S + L + K +P D L E IK + V ++
Sbjct: 261 NSSKKESESEDSSDDEPLIKKLK--------KPPTDEELKETIKKLLASANLEEVTMKQI 312
Query: 185 -KYIIHKYPSLELERRGYLLKQALK 208
K + YP+ +L R +K +K
Sbjct: 313 CKKVYENYPTYDLTERKDFIKTTVK 337
Score = 37.7 bits (86), Expect = 0.028
Identities = 22/64 (34%), Positives = 35/64 (54%), Gaps = 8/64 (12%)
Query: 427 EPDDSRDEDEDEDESS-EEDSEDEEPPPKRRLQKKTP-------AKSPGKAASVKQRGSK 478
E DE ++++ESS +ED E EE PPK+ +++ P +K K+A+VK+ S
Sbjct: 195 ESSSDEDEKKNKEESSDDEDKESEEEPPKKTAKREKPKQKATSKSKKSVKSANVKKADSS 254
Query: 479 PAPK 482
K
Sbjct: 255 TTKK 258
Score = 35.8 bits (81), Expect = 0.11
Identities = 73/353 (20%), Positives = 135/353 (38%), Gaps = 54/353 (15%)
Query: 74 SVSTVEEQENETPPATSSEAEQPKGEPENEEKEENKSSEETKKDEKDQ------------ 121
S E + T PA+ E E P G E E+EE++ EE +++EK +
Sbjct: 4 SAPAAEGEGTPTQPASEKEPEMP-GPREESEEEEDEDDEEEEEEEKGKGQKLCEIERIHF 62
Query: 122 --SKEKE-----------------KKVKKTIPSWATLSASQ-LARAQKQTPMASSPRPKM 161
SK+K +KK + ++ + + +K+ M R M
Sbjct: 63 FLSKKKTDELRNLHKLLYNRPGTVSSLKKNVGQFSGFPFEKGSVQYKKKEEMLKKFRNAM 122
Query: 162 DAILTEAIKACFQKSGAS---VVAIRKYIIHKYPS-LELERRGYLLKQALKRELNRGVIK 217
+ E + ++SG + V I +++H PS L + + K+E N +
Sbjct: 123 LKSICEVLD--LERSGVNSELVKRILNFLMHPKPSGKPLPKSKKTCSKGSKKERNSSGMA 180
Query: 218 QVKGKGASGSFVVVQKSRKTPQKSRNRKNRSSAVDPEPQVKLEDVLPLAFTRLCEPKEAS 277
+ K K ++ +S + +N++ S D E E+ P + +PK+ +
Sbjct: 181 R-KAKRTKCPEILSDESSSDEDEKKNKEESSDDEDKES----EEEPPKKTAKREKPKQKA 235
Query: 278 YSLIRKYVSQYYPKLRVDIRPQLLKNALQRAVERGQLEQITGKGASGTFQLKKSGEKPLL 337
S +K V K + +N+ ++ E + +S L K +KP
Sbjct: 236 TSKSKKSVKSANVKKADSSTTKKNQNSSKKESE--------SEDSSDDEPLIKKLKKPPT 287
Query: 338 GGSLMEYAILSAIAAMNEPKTCSTTALKKYVLENHPGTNSNYQMHLLKKTLQK 390
L E I +A+ N + KK V EN+P + + +K T+++
Sbjct: 288 DEELKE-TIKKLLASANLEEVTMKQICKK-VYENYPTYDLTERKDFIKTTVKE 338
Score = 34.7 bits (78), Expect = 0.23
Identities = 18/63 (28%), Positives = 31/63 (49%), Gaps = 1/63 (1%)
Query: 419 PGVLFPKKEPDDSRDEDEDEDESSEEDSEDEEPPPKRRLQKKTPAKSPGKA-ASVKQRGS 477
P +L + D+ ++++E E+ +EEPP K ++K K+ K+ SVK
Sbjct: 189 PEILSDESSSDEDEKKNKEESSDDEDKESEEEPPKKTAKREKPKQKATSKSKKSVKSANV 248
Query: 478 KPA 480
K A
Sbjct: 249 KKA 251
Score = 30.8 bits (68), Expect = 3.4
Identities = 29/118 (24%), Positives = 44/118 (37%), Gaps = 14/118 (11%)
Query: 430 DSRDEDEDEDESSEEDSEDEEPPPKRRLQKKTPAKSPGKAASVKQRGSKPAPKVSAAQRG 489
D DEDE ++ EE S D+E K++ + P K A + PK A +
Sbjct: 194 DESSSDEDEKKNKEE-SSDDE-------DKESEEEPPKKTA------KREKPKQKATSKS 239
Query: 490 KARPLPKKAPPKAKTPAKKTRPSSTVIKKPSGGSSKKPATSARKEVKLPGKGKSTMKK 547
K + KK + SS + S +P K+ + K T+KK
Sbjct: 240 KKSVKSANVKKADSSTTKKNQNSSKKESESEDSSDDEPLIKKLKKPPTDEELKETIKK 297
>gi|4503249 DEK oncogene isoform 1 [Homo sapiens]
Length = 375
Score = 48.5 bits (114), Expect = 2e-05
Identities = 48/205 (23%), Positives = 87/205 (42%), Gaps = 22/205 (10%)
Query: 10 LVHPKALPLIVGAQLIHADKL---GEKVEDSTMPIRRTVNSTRETPPKSKLAEGEEEKPE 66
L+HPK G L + K G K E ++ + R T+ S + +E++ +
Sbjct: 183 LMHPKPS----GKPLPKSKKTCSKGSKKERNSSGMARKAKRTKCPEILSDESSSDEDEKK 238
Query: 67 PDISSEESVSTVEEQENETPPATSSEAEQPKGEPENEEKEENKSSEETKKDEKDQSKEKE 126
+ EES +++ E PP +++ E+PK + ++ K+ KS+ KK + +K+ +
Sbjct: 239 ---NKEESSDDEDKESEEEPPKKTAKREKPKQKATSKSKKSVKSA-NVKKADSSTTKKNQ 294
Query: 127 KKVKKTIPSWATLSASQLARAQKQTPMASSPRPKMDAILTEAIKACFQKSGASVVAIR-- 184
KK S + L + K +P D L E IK + V ++
Sbjct: 295 NSSKKESESEDSSDDEPLIKKLK--------KPPTDEELKETIKKLLASANLEEVTMKQI 346
Query: 185 -KYIIHKYPSLELERRGYLLKQALK 208
K + YP+ +L R +K +K
Sbjct: 347 CKKVYENYPTYDLTERKDFIKTTVK 371
Score = 40.8 bits (94), Expect = 0.003
Identities = 25/73 (34%), Positives = 37/73 (50%), Gaps = 1/73 (1%)
Query: 74 SVSTVEEQENETPPATSSEAEQPKGEPENEEKEENKSSEETKKDEKDQSKEKEKKVKKTI 133
S E + T PA+ E E P G E E+EE++ EE +++EK++S E K +K
Sbjct: 4 SAPAAEGEGTPTQPASEKEPEMP-GPREESEEEEDEDDEEEEEEEKEKSLIVEGKREKKK 62
Query: 134 PSWATLSASQLAR 146
T+ S L R
Sbjct: 63 VERLTMQVSSLQR 75
Score = 37.7 bits (86), Expect = 0.028
Identities = 22/64 (34%), Positives = 35/64 (54%), Gaps = 8/64 (12%)
Query: 427 EPDDSRDEDEDEDESS-EEDSEDEEPPPKRRLQKKTP-------AKSPGKAASVKQRGSK 478
E DE ++++ESS +ED E EE PPK+ +++ P +K K+A+VK+ S
Sbjct: 229 ESSSDEDEKKNKEESSDDEDKESEEEPPKKTAKREKPKQKATSKSKKSVKSANVKKADSS 288
Query: 479 PAPK 482
K
Sbjct: 289 TTKK 292
Score = 34.7 bits (78), Expect = 0.23
Identities = 18/63 (28%), Positives = 31/63 (49%), Gaps = 1/63 (1%)
Query: 419 PGVLFPKKEPDDSRDEDEDEDESSEEDSEDEEPPPKRRLQKKTPAKSPGKA-ASVKQRGS 477
P +L + D+ ++++E E+ +EEPP K ++K K+ K+ SVK
Sbjct: 223 PEILSDESSSDEDEKKNKEESSDDEDKESEEEPPKKTAKREKPKQKATSKSKKSVKSANV 282
Query: 478 KPA 480
K A
Sbjct: 283 KKA 285
Score = 30.8 bits (68), Expect = 3.4
Identities = 29/118 (24%), Positives = 44/118 (37%), Gaps = 14/118 (11%)
Query: 430 DSRDEDEDEDESSEEDSEDEEPPPKRRLQKKTPAKSPGKAASVKQRGSKPAPKVSAAQRG 489
D DEDE ++ EE S D+E K++ + P K A + PK A +
Sbjct: 228 DESSSDEDEKKNKEE-SSDDE-------DKESEEEPPKKTA------KREKPKQKATSKS 273
Query: 490 KARPLPKKAPPKAKTPAKKTRPSSTVIKKPSGGSSKKPATSARKEVKLPGKGKSTMKK 547
K + KK + SS + S +P K+ + K T+KK
Sbjct: 274 KKSVKSANVKKADSSTTKKNQNSSKKESESEDSSDDEPLIKKLKKPPTDEELKETIKK 331
Score = 29.6 bits (65), Expect = 7.5
Identities = 12/33 (36%), Positives = 20/33 (60%)
Query: 425 KKEPDDSRDEDEDEDESSEEDSEDEEPPPKRRL 457
+KEP+ +E E+E E+D E+EE ++ L
Sbjct: 20 EKEPEMPGPREESEEEEDEDDEEEEEEEKEKSL 52
>gi|94536805 splicing factor YT521-B isoform 2 [Homo sapiens]
Length = 709
Score = 48.1 bits (113), Expect = 2e-05
Identities = 27/93 (29%), Positives = 44/93 (47%), Gaps = 4/93 (4%)
Query: 32 EKVEDSTMPIRRTVNSTRETPPKSKLAEGEEEKPEPDISSEESVSTVEEQENETPPATSS 91
E+V S+ + + E EEE E D+ +E V E++ E
Sbjct: 172 EEVNSEEYGSDHETGSSGSSDEQGNNTENEEEGVEEDVEEDEEVEEDAEEDEEV----DE 227
Query: 92 EAEQPKGEPENEEKEENKSSEETKKDEKDQSKE 124
+ E+ + E E EE+EE + EE ++DE+DQ +E
Sbjct: 228 DGEEEEEEEEEEEEEEEEEEEEYEQDERDQKEE 260
Score = 34.3 bits (77), Expect = 0.31
Identities = 26/112 (23%), Positives = 44/112 (39%), Gaps = 2/112 (1%)
Query: 427 EPDDSRDEDEDEDESSEEDSEDEEPPPKRRL-QKKTPAKSPGKAASVKQRGSKPAPKVSA 485
E D+ DED +E+E EE+ E+EE + Q + K G + S + +
Sbjct: 220 EEDEEVDEDGEEEEEEEEEEEEEEEEEEEEYEQDERDQKEEGNDYDTRSEASDSGSESVS 279
Query: 486 AQRGKARP-LPKKAPPKAKTPAKKTRPSSTVIKKPSGGSSKKPATSARKEVK 536
G R + K K+ R S ++ SG S+ + ++K
Sbjct: 280 FTDGSVRSGSGTDGSDEKKKERKRARGISPIVFDRSGSSASESYADQTSKLK 331
Score = 32.0 bits (71), Expect = 1.5
Identities = 41/207 (19%), Positives = 77/207 (37%), Gaps = 30/207 (14%)
Query: 27 ADKLGEKVEDSTMPIRRTVNSTRETPPKSKLAEGEEEKPEPDISSEESVSTVEEQENETP 86
+D+ G E+ + V E + E EE E D EE EE+E E
Sbjct: 191 SDEQGNNTENEEEGVEEDVEEDEE------VEEDAEEDEEVDEDGEEE---EEEEEEE-- 239
Query: 87 PATSSEAEQPKGEPENEEKEENKSSEETKKDEKDQSKEKEKKVKKTIPSWATLSASQLAR 146
E E+ + E + +++E + +T+ + D E ++ S + S +
Sbjct: 240 -EEEEEEEEEEYEQDERDQKEEGNDYDTRSEASDSGSESVSFTDGSVRSGSGTDGSDEKK 298
Query: 147 AQKQTPMASSPRPKMDAILTEAIKACFQKSGASVVAIRKYIIHKYPSLELERRGYLLKQA 206
+++ SP I+ + + +S A + KY++ + R +L+K
Sbjct: 299 KERKRARGISP------IVFDRSGSSASESYADQTSKLKYVLQ-------DARFFLIKSN 345
Query: 207 LKRELNRGVIKQVKGKGASGSFVVVQK 233
N + K KG + V +K
Sbjct: 346 -----NHENVSLAKAKGVWSTLPVNEK 367
Score = 30.4 bits (67), Expect = 4.4
Identities = 12/24 (50%), Positives = 17/24 (70%)
Query: 427 EPDDSRDEDEDEDESSEEDSEDEE 450
E D+ +ED +EDE +ED E+EE
Sbjct: 210 EEDEEVEEDAEEDEEVDEDGEEEE 233
Score = 29.3 bits (64), Expect = 9.8
Identities = 20/93 (21%), Positives = 42/93 (45%)
Query: 36 DSTMPIRRTVNSTRETPPKSKLAEGEEEKPEPDISSEESVSTVEEQENETPPATSSEAEQ 95
D + I V+ +S E E+ D + S S+ E+ N E +
Sbjct: 150 DGSERIGLEVDRRASRSSQSSKEEVNSEEYGSDHETGSSGSSDEQGNNTENEEEGVEEDV 209
Query: 96 PKGEPENEEKEENKSSEETKKDEKDQSKEKEKK 128
+ E E+ EE++ +E ++E+++ +E+E++
Sbjct: 210 EEDEEVEEDAEEDEEVDEDGEEEEEEEEEEEEE 242
>gi|72534750 splicing factor YT521-B isoform 1 [Homo sapiens]
Length = 727
Score = 48.1 bits (113), Expect = 2e-05
Identities = 27/93 (29%), Positives = 44/93 (47%), Gaps = 4/93 (4%)
Query: 32 EKVEDSTMPIRRTVNSTRETPPKSKLAEGEEEKPEPDISSEESVSTVEEQENETPPATSS 91
E+V S+ + + E EEE E D+ +E V E++ E
Sbjct: 172 EEVNSEEYGSDHETGSSGSSDEQGNNTENEEEGVEEDVEEDEEVEEDAEEDEEV----DE 227
Query: 92 EAEQPKGEPENEEKEENKSSEETKKDEKDQSKE 124
+ E+ + E E EE+EE + EE ++DE+DQ +E
Sbjct: 228 DGEEEEEEEEEEEEEEEEEEEEYEQDERDQKEE 260
Score = 36.2 bits (82), Expect = 0.081
Identities = 31/123 (25%), Positives = 52/123 (42%), Gaps = 5/123 (4%)
Query: 426 KEPDDSRDEDEDEDESSEEDSEDEEPPPKRRLQKKTPAKSPGKAASVKQRGSKPAPKVSA 485
+E D+ +E+E+E+E EE+ E+EE + Q + K G + S + +
Sbjct: 223 EEVDEDGEEEEEEEEEEEEEEEEEE---EEYEQDERDQKEEGNDYDTRSEASDSGSESVS 279
Query: 486 AQRGKARP-LPKKAPPKAKTPAKKTRPSSTVIKKPSGGS-SKKPATSARKEVKLPGKGKS 543
G R + K K+ R S ++ SG S S+ A S +K KL ++
Sbjct: 280 FTDGSVRSGSGTDGSDEKKKERKRARGISPIVFDRSGSSASESYAGSEKKHEKLSSSVRA 339
Query: 544 TMK 546
K
Sbjct: 340 VRK 342
Score = 34.7 bits (78), Expect = 0.23
Identities = 46/212 (21%), Positives = 81/212 (38%), Gaps = 22/212 (10%)
Query: 27 ADKLGEKVEDSTMPIRRTVNSTRETPPKSKLAEGEEEKPEPDISSEESVSTVEEQENETP 86
+D+ G E+ + V E + E EE E D EE EE+E E
Sbjct: 191 SDEQGNNTENEEEGVEEDVEEDEE------VEEDAEEDEEVDEDGEEE---EEEEEEE-- 239
Query: 87 PATSSEAEQPKGEPENEEKEENKSSEETKKDEKDQSKEKEKKVKKTIPSWATLSASQLAR 146
E E+ + E + +++E + +T+ + D E ++ S + S +
Sbjct: 240 -EEEEEEEEEEYEQDERDQKEEGNDYDTRSEASDSGSESVSFTDGSVRSGSGTDGSDEKK 298
Query: 147 AQKQTPMASSP----RPKMDAILTEA-IKACFQKSGASVVAIRKYIIHKYPSLELERRGY 201
+++ SP R A + A + +K +SV A+RK K + + R +
Sbjct: 299 KERKRARGISPIVFDRSGSSASESYAGSEKKHEKLSSSVRAVRKDQTSKLKYVLQDARFF 358
Query: 202 LLKQALKRELNRGVIKQVKGKGASGSFVVVQK 233
L+K N + K KG + V +K
Sbjct: 359 LIKSN-----NHENVSLAKAKGVWSTLPVNEK 385
Score = 29.3 bits (64), Expect = 9.8
Identities = 20/93 (21%), Positives = 42/93 (45%)
Query: 36 DSTMPIRRTVNSTRETPPKSKLAEGEEEKPEPDISSEESVSTVEEQENETPPATSSEAEQ 95
D + I V+ +S E E+ D + S S+ E+ N E +
Sbjct: 150 DGSERIGLEVDRRASRSSQSSKEEVNSEEYGSDHETGSSGSSDEQGNNTENEEEGVEEDV 209
Query: 96 PKGEPENEEKEENKSSEETKKDEKDQSKEKEKK 128
+ E E+ EE++ +E ++E+++ +E+E++
Sbjct: 210 EEDEEVEEDAEEDEEVDEDGEEEEEEEEEEEEE 242
>gi|83641870 nucleophosmin 1 isoform 3 [Homo sapiens]
Length = 259
Score = 47.8 bits (112), Expect = 3e-05
Identities = 28/79 (35%), Positives = 40/79 (50%), Gaps = 5/79 (6%)
Query: 427 EPDDSRDEDEDEDESSEEDSEDEEPPPKRRLQKKTPAKSPGKAASVKQRGSKPAPKVSAA 486
+ DD D+DED+D+ +D E EE P ++ + TPAK+ K+ Q G P S+
Sbjct: 165 DDDDEEDDDEDDDDDDFDDEEAEEKAPVKKSIRDTPAKNAQKS---NQNGKDSKP--SST 219
Query: 487 QRGKARPLPKKAPPKAKTP 505
R K + KK KTP
Sbjct: 220 PRSKGQESFKKQEKTPKTP 238
Score = 40.0 bits (92), Expect = 0.006
Identities = 26/104 (25%), Positives = 47/104 (45%), Gaps = 5/104 (4%)
Query: 62 EEKPEPDISSEESVSTVEEQENETPPATSSEAEQPK-----GEPENEEKEENKSSEETKK 116
EE E + EE V + + P S+ Q K E ++++ EE+ ++
Sbjct: 120 EEDAESEDEEEEDVKLLSISGKRSAPGGGSKVPQKKVKLAADEDDDDDDEEDDDEDDDDD 179
Query: 117 DEKDQSKEKEKKVKKTIPSWATLSASQLARAQKQTPMASSPRPK 160
D D+ E++ VKK+I +A + + K + +S+PR K
Sbjct: 180 DFDDEEAEEKAPVKKSIRDTPAKNAQKSNQNGKDSKPSSTPRSK 223
>gi|39780597 PNMA-like 1 isoform a [Homo sapiens]
Length = 439
Score = 47.8 bits (112), Expect = 3e-05
Identities = 35/124 (28%), Positives = 56/124 (45%), Gaps = 14/124 (11%)
Query: 424 PKKEPDDSRDEDEDEDESSEEDSED-EEPPPKRRLQKKTPAKSPGKAASVKQRGSKPAPK 482
P++ P D+R E E +SE D + E PPK++ AK+P K+ P
Sbjct: 315 PREPPQDARAEAESPGGASESDQDGGHESPPKKKAVAWVSAKNPAPMRKKKKVSLGPVSY 374
Query: 483 VSA-AQRGKARP-LPKKAP-----------PKAKTPAKKTRPSSTVIKKPSGGSSKKPAT 529
V ++ G+ +P +PKK P P+ + PA+ T +S K GS ++
Sbjct: 375 VLVDSEDGRKKPVMPKKGPGSRREASDQKAPRGQQPAEATASTSRGPKAKPEGSPRRATN 434
Query: 530 SARK 533
+RK
Sbjct: 435 ESRK 438
>gi|21361272 myeloid/lymphoid or mixed-lineage leukemia (trithorax
homolog, Drosophila); translocated to, 1 [Homo sapiens]
Length = 559
Score = 47.4 bits (111), Expect = 3e-05
Identities = 34/136 (25%), Positives = 63/136 (46%), Gaps = 16/136 (11%)
Query: 424 PKKEPDD---SRDEDEDEDESSEEDS----------EDEEPPPKRRLQKKTPAKSPGKAA 470
P+K+ + S++ + ++ +SS++ S E++ PPPK ++ A K
Sbjct: 205 PRKDSESKSSSKELEREQAKSSKDTSRKLGEGRLPKEEKAPPPKAAFKEPKMALKETKLE 264
Query: 471 SVKQRGSKPAPKVSAAQRGKARPLPKKAPPKAKTPAKKTRPSSTVIKKPSGGSSKKPATS 530
S +G P P + RP +P K AKK + SS+ + + G+S + ++S
Sbjct: 265 STSPKGGPPPPPPPPPRASSKRPATADSP---KPSAKKQKKSSSKGSRSAPGTSPRTSSS 321
Query: 531 ARKEVKLPGKGKSTMK 546
+ K P K KS+ +
Sbjct: 322 SSFSDKKPAKDKSSTR 337
Score = 31.6 bits (70), Expect = 2.0
Identities = 32/125 (25%), Positives = 51/125 (40%), Gaps = 38/125 (30%)
Query: 42 RRTVNSTRETPPKSKLAEG----EEEKPEPDISSEESVSTVEEQENET------------ 85
R S+++T KL EG EE+ P P + +E ++E + E+
Sbjct: 220 REQAKSSKDT--SRKLGEGRLPKEEKAPPPKAAFKEPKMALKETKLESTSPKGGPPPPPP 277
Query: 86 -PPATSSE----AEQPKGEPENEEKEENKSSEET---------------KKDEKDQSKEK 125
PP SS+ A+ PK + ++K +K S KK KD+S +
Sbjct: 278 PPPRASSKRPATADSPKPSAKKQKKSSSKGSRSAPGTSPRTSSSSSFSDKKPAKDKSSTR 337
Query: 126 EKKVK 130
+KVK
Sbjct: 338 GEKVK 342
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.306 0.124 0.340
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 24,278,503
Number of Sequences: 37866
Number of extensions: 1352364
Number of successful extensions: 31907
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 807
Number of HSP's successfully gapped in prelim test: 1049
Number of HSP's that attempted gapping in prelim test: 11477
Number of HSP's gapped (non-prelim): 13902
length of query: 553
length of database: 18,247,518
effective HSP length: 107
effective length of query: 446
effective length of database: 14,195,856
effective search space: 6331351776
effective search space used: 6331351776
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 43 (22.0 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.