BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|56550065 complexin 2 [Homo sapiens] (134 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|56550065 complexin 2 [Homo sapiens] 269 6e-73 gi|5729783 complexin 2 [Homo sapiens] 269 6e-73 gi|5729781 complexin 1 [Homo sapiens] 228 1e-60 gi|71725345 complexin 3 [Homo sapiens] 62 2e-10 gi|66792814 retrotransposon gag domain containing 4 [Homo sapiens] 55 2e-08 gi|148746183 ubiquitin specific protease 35 [Homo sapiens] 54 3e-08 gi|221219020 NYD-SP11 protein [Homo sapiens] 50 7e-07 gi|239754909 PREDICTED: hypothetical protein [Homo sapiens] 49 9e-07 gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-li... 49 1e-06 gi|148746195 trichohyalin [Homo sapiens] 47 4e-06 gi|22758136 MAP7 domain containing 2 [Homo sapiens] 47 4e-06 gi|31795561 complexin 4 [Homo sapiens] 47 5e-06 gi|55741709 RNA binding motif protein 25 [Homo sapiens] 45 2e-05 gi|239745079 PREDICTED: Putative golgin subfamily A member 6-lik... 45 2e-05 gi|78190492 retinitis pigmentosa GTPase regulator isoform C [Hom... 44 3e-05 gi|157738649 neurofilament, medium polypeptide 150kDa isoform 1 ... 44 4e-05 gi|157738641 neurofilament, medium polypeptide 150kDa isoform 2 ... 44 4e-05 gi|239508778 PREDICTED: hypothetical protein, partial [Homo sapi... 44 5e-05 gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo sa... 43 7e-05 gi|115298682 HBxAg transactivated protein 2 [Homo sapiens] 43 7e-05 gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo sa... 42 1e-04 gi|195927037 DNA (cytosine-5-)-methyltransferase 1 isoform a [Ho... 42 1e-04 gi|4503351 DNA (cytosine-5-)-methyltransferase 1 isoform b [Homo... 42 1e-04 gi|148806928 hypothetical protein LOC57482 [Homo sapiens] 42 1e-04 gi|155030232 proline, glutamic acid and leucine rich protein 1 [... 42 1e-04 gi|18426913 drebrin 1 isoform b [Homo sapiens] 42 1e-04 gi|18426915 drebrin 1 isoform a [Homo sapiens] 42 1e-04 gi|239749449 PREDICTED: hypothetical protein [Homo sapiens] 42 2e-04 gi|40254924 leucine rich repeat containing 59 [Homo sapiens] 42 2e-04 gi|190684694 ubiquitin specific peptidase 8 [Homo sapiens] 42 2e-04 >gi|56550065 complexin 2 [Homo sapiens] Length = 134 Score = 269 bits (687), Expect = 6e-73 Identities = 134/134 (100%), Positives = 134/134 (100%) Query: 1 MDFVMKQALGGATKDMGKMLGGEEEKDPDAQKKEEERQEALRQQEEERKAKHARMEAERE 60 MDFVMKQALGGATKDMGKMLGGEEEKDPDAQKKEEERQEALRQQEEERKAKHARMEAERE Sbjct: 1 MDFVMKQALGGATKDMGKMLGGEEEKDPDAQKKEEERQEALRQQEEERKAKHARMEAERE 60 Query: 61 KVRQQIRDKYGLKKKEEKEAEEKAALEQPCEGSLTRPKKAIPAGCGDEEEEEEESILDTV 120 KVRQQIRDKYGLKKKEEKEAEEKAALEQPCEGSLTRPKKAIPAGCGDEEEEEEESILDTV Sbjct: 61 KVRQQIRDKYGLKKKEEKEAEEKAALEQPCEGSLTRPKKAIPAGCGDEEEEEEESILDTV 120 Query: 121 LKYLPGPLQDMFKK 134 LKYLPGPLQDMFKK Sbjct: 121 LKYLPGPLQDMFKK 134 >gi|5729783 complexin 2 [Homo sapiens] Length = 134 Score = 269 bits (687), Expect = 6e-73 Identities = 134/134 (100%), Positives = 134/134 (100%) Query: 1 MDFVMKQALGGATKDMGKMLGGEEEKDPDAQKKEEERQEALRQQEEERKAKHARMEAERE 60 MDFVMKQALGGATKDMGKMLGGEEEKDPDAQKKEEERQEALRQQEEERKAKHARMEAERE Sbjct: 1 MDFVMKQALGGATKDMGKMLGGEEEKDPDAQKKEEERQEALRQQEEERKAKHARMEAERE 60 Query: 61 KVRQQIRDKYGLKKKEEKEAEEKAALEQPCEGSLTRPKKAIPAGCGDEEEEEEESILDTV 120 KVRQQIRDKYGLKKKEEKEAEEKAALEQPCEGSLTRPKKAIPAGCGDEEEEEEESILDTV Sbjct: 61 KVRQQIRDKYGLKKKEEKEAEEKAALEQPCEGSLTRPKKAIPAGCGDEEEEEEESILDTV 120 Query: 121 LKYLPGPLQDMFKK 134 LKYLPGPLQDMFKK Sbjct: 121 LKYLPGPLQDMFKK 134 >gi|5729781 complexin 1 [Homo sapiens] Length = 134 Score = 228 bits (581), Expect = 1e-60 Identities = 113/134 (84%), Positives = 123/134 (91%) Query: 1 MDFVMKQALGGATKDMGKMLGGEEEKDPDAQKKEEERQEALRQQEEERKAKHARMEAERE 60 M+FVMKQALGGATKDMGKMLGG+EEKDPDA KKEEERQEALRQ EEERKAK+A+MEAERE Sbjct: 1 MEFVMKQALGGATKDMGKMLGGDEEKDPDAAKKEEERQEALRQAEEERKAKYAKMEAERE 60 Query: 61 KVRQQIRDKYGLKKKEEKEAEEKAALEQPCEGSLTRPKKAIPAGCGDEEEEEEESILDTV 120 VRQ IRDKYG+KKKEE+EAE +AA+E EGSLTRPKKAIP GCGDE EEE+ESILDTV Sbjct: 61 AVRQGIRDKYGIKKKEEREAEAQAAMEANSEGSLTRPKKAIPPGCGDEVEEEDESILDTV 120 Query: 121 LKYLPGPLQDMFKK 134 +KYLPGPLQDM KK Sbjct: 121 IKYLPGPLQDMLKK 134 >gi|71725345 complexin 3 [Homo sapiens] Length = 158 Score = 61.6 bits (148), Expect = 2e-10 Identities = 45/136 (33%), Positives = 70/136 (51%), Gaps = 15/136 (11%) Query: 1 MDFVMKQALGGATKDM-GKMLGGEEEKDPDAQKKE---------EERQEALRQQEEERKA 50 M F++K +GG K++ G + GGE++ D D E EE Q+ L +++ ER A Sbjct: 1 MAFMVKTMVGGQLKNLTGSLGGGEDKGDGDKSAAEAQGMSREEYEEYQKQLVEEKMERDA 60 Query: 51 KHARMEAEREKVRQQIRDKYGLKKKEEKEAEEKAALEQPCEGSLTRPKKAIPAGCGDEEE 110 + + +AER +R RDKY L K E E++ + A G + P++ D EE Sbjct: 61 QFTQRKAERATLRSHFRDKYRLPKNETDESQIQMA-----GGDVELPRELAKMIEEDTEE 115 Query: 111 EEEESILDTVLKYLPG 126 EEE++ + L LPG Sbjct: 116 EEEKASVLGQLASLPG 131 >gi|66792814 retrotransposon gag domain containing 4 [Homo sapiens] Length = 569 Score = 55.1 bits (131), Expect = 2e-08 Identities = 32/95 (33%), Positives = 53/95 (55%), Gaps = 3/95 (3%) Query: 23 EEEKDPDAQKKEEERQEALRQQ---EEERKAKHARMEAEREKVRQQIRDKYGLKKKEEKE 79 EEE + + E+E QEA R + +++RK A + +EK ++++ + +KKKEEKE Sbjct: 335 EEESEDEEYYSEDEDQEARRHRLHSKDQRKRMRAFQQEMKEKEEEEMKKEEEMKKKEEKE 394 Query: 80 AEEKAALEQPCEGSLTRPKKAIPAGCGDEEEEEEE 114 EE+ ++Q E R K DEE+E+E+ Sbjct: 395 EEEEEEMKQKEEEEEIRNKNEEEGESKDEEDEDED 429 Score = 38.1 bits (87), Expect = 0.002 Identities = 27/90 (30%), Positives = 49/90 (54%), Gaps = 4/90 (4%) Query: 31 QKKEEERQEALRQQEEERKAKHARMEAEREKVRQQIRDKYGLKKKEEKEAEEKAALEQPC 90 Q++ +E++E ++EEE K K + E E E+++Q+ ++ ++ K E+E E K ++ Sbjct: 370 QQEMKEKEEEEMKKEEEMKKKEEKEEEEEEEMKQK-EEEEEIRNKNEEEGESKDEEDEDE 428 Query: 91 EGSLTRPKKAIPAGCGDEEE--EEEESILD 118 +G +P+ G EE E EE LD Sbjct: 429 DGG-QKPEGEPQQDPGTEETYGEVEEEPLD 457 Score = 34.7 bits (78), Expect = 0.024 Identities = 19/65 (29%), Positives = 38/65 (58%), Gaps = 1/65 (1%) Query: 23 EEEKDPDAQKKEEERQEALRQQEEERKAKHARMEAEREKVRQQIRDKYGLKKKEEKEAEE 82 +EE+ ++KEEE +E ++Q+EEE + ++ + E E E ++ D+ G +K E + ++ Sbjct: 383 KEEEMKKKEEKEEEEEEEMKQKEEEEEIRN-KNEEEGESKDEEDEDEDGGQKPEGEPQQD 441 Query: 83 KAALE 87 E Sbjct: 442 PGTEE 446 >gi|148746183 ubiquitin specific protease 35 [Homo sapiens] Length = 1018 Score = 54.3 bits (129), Expect = 3e-08 Identities = 33/107 (30%), Positives = 58/107 (54%), Gaps = 2/107 (1%) Query: 18 KMLGGEEEKDPDAQKKEEERQEALRQQEEERKAKHARMEAEREKVRQQIRDKYGLKKKEE 77 K GG+ ++ +++EE ++E ++E + + R E EREK + ++ ++K+ E Sbjct: 665 KEAGGQSSQEERIEREEEGKEERTEKEEVGEEEESTRGEGEREKEEEVEEEEEKVEKETE 724 Query: 78 KEAEEKAALEQPCEGSLTRPKKAIPAGCGDEEEEEEESILDTVLKYL 124 KEAE++ E+ G+ T P AIP+G E S+LD V +L Sbjct: 725 KEAEQEK--EEDSLGAGTHPDAAIPSGERTCGSEGSRSVLDLVNYFL 769 >gi|221219020 NYD-SP11 protein [Homo sapiens] Length = 2873 Score = 49.7 bits (117), Expect = 7e-07 Identities = 31/94 (32%), Positives = 52/94 (55%), Gaps = 5/94 (5%) Query: 25 EKDPDAQKKEEERQEALRQQEEERKAKHARMEAEREKVRQQIRDKYGLKKKEEKEAEEKA 84 E++ + +++EE +E +R++EEERK + E E ++V ++ +K KKK+EK+ EE Sbjct: 2246 EEEEEREEEEEREEEEVREEEEERKEEE---EGEEKQVEKEEEEK--KKKKKEKKKEEVQ 2300 Query: 85 ALEQPCEGSLTRPKKAIPAGCGDEEEEEEESILD 118 E+ E + DEEEEEE L+ Sbjct: 2301 EKEEVFEEKEEIMSEEETESLSDEEEEEESCSLE 2334 Score = 36.2 bits (82), Expect = 0.008 Identities = 26/67 (38%), Positives = 37/67 (55%), Gaps = 3/67 (4%) Query: 23 EEEKDPDAQKKEEERQEALRQ-QEEERKAKHARMEAEREKVRQQIRDKYGLKKKEEKEAE 81 EEE + ++KE++ E R QEE + A+ R A EK R Q K L ++EEK A+ Sbjct: 1547 EEEVSREGEEKEQQVTEEQRHIQEEHKWARIHRKRARAEKKRAQEERK--LAQEEEKLAQ 1604 Query: 82 EKAALEQ 88 E+ L Q Sbjct: 1605 EERQLAQ 1611 Score = 33.1 bits (74), Expect = 0.069 Identities = 24/80 (30%), Positives = 40/80 (50%), Gaps = 3/80 (3%) Query: 20 LGGEEEKDPDAQKKEEERQEALRQQEEERKAKHARMEAEREKVRQQIRDKYGLKKKEEKE 79 L EE K + +KK E +EAL Q E+ + ++ E E + I++K L + +EK Sbjct: 1735 LNQEEGKLVEEKKKLAEEEEALAWQREKLSEEETKLAQEEELL---IQEKEKLAQHKEKM 1791 Query: 80 AEEKAALEQPCEGSLTRPKK 99 EE+ L + E + + K Sbjct: 1792 PEEEERLGRKREQLIEKKMK 1811 Score = 32.7 bits (73), Expect = 0.089 Identities = 28/81 (34%), Positives = 41/81 (50%), Gaps = 7/81 (8%) Query: 44 QEEERKAKHARMEAEREKVRQQIRDKYGLKKKEEKEAEEKAALEQPCEGSLTRPKKAIPA 103 QE+E K AE EK Q+ D L KK+EK A+EK L E ++ + KK + Sbjct: 1897 QEKETVIKKKEKLAETEKKLVQVEDS--LAKKQEKLAQEKMKL--ALEKAMVQGKKRLR- 1951 Query: 104 GCGDEEEEEEESILDTVLKYL 124 G+ + +EE L+ +K L Sbjct: 1952 --GELDIAKEEKALNLEMKRL 1970 Score = 30.4 bits (67), Expect = 0.44 Identities = 16/66 (24%), Positives = 38/66 (57%), Gaps = 1/66 (1%) Query: 23 EEEKDPDAQKKEEERQEALRQQEEERKAKHARMEAEREKVRQQIRDKYGLKKKEEKEAEE 82 EEE+ + Q ++EE ++ +++E++++ + E EK + + ++ +E+E EE Sbjct: 2271 EEEEGEEKQVEKEEEEKKKKKKEKKKEEVQEKEEVFEEK-EEIMSEEETESLSDEEEEEE 2329 Query: 83 KAALEQ 88 +LE+ Sbjct: 2330 SCSLEE 2335 Score = 30.4 bits (67), Expect = 0.44 Identities = 16/62 (25%), Positives = 37/62 (59%), Gaps = 1/62 (1%) Query: 23 EEEKDPDAQKKEEERQEALRQQEEERKAKHARM-EAEREKVRQQIRDKYGLKKKEEKEAE 81 E+E++ +KK+E+++E ++++EE + K M E E E + + ++ +EE + E Sbjct: 2281 EKEEEEKKKKKKEKKKEEVQEKEEVFEEKEEIMSEEETESLSDEEEEEESCSLEEEVDRE 2340 Query: 82 EK 83 ++ Sbjct: 2341 KE 2342 Score = 28.9 bits (63), Expect = 1.3 Identities = 26/102 (25%), Positives = 46/102 (45%), Gaps = 10/102 (9%) Query: 23 EEEKDPDAQKKEEERQEALR----------QQEEERKAKHARMEAEREKVRQQIRDKYGL 72 EEE P +++ +R+EA R Q +E +H E E + ++ Sbjct: 2186 EEEVIPFLKRRWRKRKEAKRGDKPKEKFSSQVDEVESEEHFSEEMESLLDELEKQESLSS 2245 Query: 73 KKKEEKEAEEKAALEQPCEGSLTRPKKAIPAGCGDEEEEEEE 114 +++EE+E EE+ E+ E R ++ E+EEEE+ Sbjct: 2246 EEEEEREEEEEREEEEVREEEEERKEEEEGEEKQVEKEEEEK 2287 Score = 28.9 bits (63), Expect = 1.3 Identities = 17/64 (26%), Positives = 35/64 (54%), Gaps = 3/64 (4%) Query: 23 EEEKDPDAQKKEE---ERQEALRQQEEERKAKHARMEAEREKVRQQIRDKYGLKKKEEKE 79 +E+K + Q+KEE E++E + ++E E + E + R+K LKK+++ + Sbjct: 2292 KEKKKEEVQEKEEVFEEKEEIMSEEETESLSDEEEEEESCSLEEEVDREKEILKKEKQFK 2351 Query: 80 AEEK 83 +E+ Sbjct: 2352 LQEQ 2355 Score = 28.5 bits (62), Expect = 1.7 Identities = 17/59 (28%), Positives = 32/59 (54%), Gaps = 4/59 (6%) Query: 24 EEKDPDAQKKEE----ERQEALRQQEEERKAKHARMEAEREKVRQQIRDKYGLKKKEEK 78 +EK+ ++KEE E E+L +EEE ++ E +REK + ++ L+++ K Sbjct: 2300 QEKEEVFEEKEEIMSEEETESLSDEEEEEESCSLEEEVDREKEILKKEKQFKLQEQRRK 2358 Score = 28.1 bits (61), Expect = 2.2 Identities = 19/59 (32%), Positives = 30/59 (50%), Gaps = 1/59 (1%) Query: 30 AQKKEEERQEALRQQEEERKAKHARMEAEREKVRQQIRDKYGLKKKEEKEAEEKAALEQ 88 A+KK + + L Q EEE+ A+ R A+ E+ Q K +E +AE K A ++ Sbjct: 1584 AEKKRAQEERKLAQ-EEEKLAQEERQLAQEERKLAQAYVKITQDDREMAQAEGKFAQKE 1641 Score = 27.7 bits (60), Expect = 2.9 Identities = 22/81 (27%), Positives = 38/81 (46%), Gaps = 6/81 (7%) Query: 24 EEKDPDAQKKEEERQEALRQQE-----EERKAKHARMEAEREKVRQQIRDKYGLKKKEEK 78 E+K ++K + +E L Q+E EERK A ++ ++ R+ + + +KEE Sbjct: 1585 EKKRAQEERKLAQEEEKLAQEERQLAQEERKLAQAYVKITQDD-REMAQAEGKFAQKEET 1643 Query: 79 EAEEKAALEQPCEGSLTRPKK 99 A+ L Q E + KK Sbjct: 1644 LAQRGEKLSQEAEKLAQKRKK 1664 Score = 27.7 bits (60), Expect = 2.9 Identities = 34/121 (28%), Positives = 56/121 (46%), Gaps = 17/121 (14%) Query: 6 KQALGGATKDMGKMLGGEEEKDPDAQKKEEERQEALRQQEEERKAKHARMEAEREKVRQQ 65 +Q L K++ + L E + KEEE QEE + + + AE E+ Sbjct: 1704 EQNLDWQEKELAQELEELEWDMEELSWKEEE-----LNQEEGKLVEEKKKLAEEEEALAW 1758 Query: 66 IRDKYGLKKKEEKEAEEKAALEQPCEGSLTRPKKAIPAGCGDEEEE----EEESILDTVL 121 R+K L ++E K A+E+ L Q E L + K+ +P EEEE + E +++ + Sbjct: 1759 QREK--LSEEETKLAQEEELLIQEKE-KLAQHKEKMP-----EEEERLGRKREQLIEKKM 1810 Query: 122 K 122 K Sbjct: 1811 K 1811 Score = 26.9 bits (58), Expect = 4.9 Identities = 19/79 (24%), Positives = 39/79 (49%), Gaps = 4/79 (5%) Query: 17 GKMLGGEEEKDPDAQKKEEERQEALRQQEEERKAKHARMEAEREKVRQQIRD----KYGL 72 G+ L E EK +KK ++ E + ++EE+ K ++ + + Q++ + + L Sbjct: 1648 GEKLSQEAEKLAQKRKKLAKKWEKVAREEEKLAKKGGKLAEVKNILAQKVEELPQREQNL 1707 Query: 73 KKKEEKEAEEKAALEQPCE 91 +E++ A+E LE E Sbjct: 1708 DWQEKELAQELEELEWDME 1726 Score = 26.9 bits (58), Expect = 4.9 Identities = 23/83 (27%), Positives = 40/83 (48%), Gaps = 12/83 (14%) Query: 24 EEKDPDAQKKEE--ERQEALRQQEEERKAKHARMEAERE----------KVRQQIRDKYG 71 +EK+ AQ KE+ E +E L ++ E+ K ++ +RE K + + K Sbjct: 1779 QEKEKLAQHKEKMPEEEERLGRKREQLIEKKMKLAQKRERWINSMEELTKNKMILYQKKN 1838 Query: 72 LKKKEEKEAEEKAALEQPCEGSL 94 L ++++ A+EK L Q E L Sbjct: 1839 LAQEKKNLAQEKEKLAQRKENLL 1861 Score = 26.6 bits (57), Expect = 6.4 Identities = 24/84 (28%), Positives = 36/84 (42%), Gaps = 10/84 (11%) Query: 5 MKQALGGATKDMGKMLGGEEEKDPDAQKKEEE-----RQEALRQQEEERKAKHARMEAER 59 + Q G ++ K+ EE +K EE ++E L QE+E+ A+H E Sbjct: 1735 LNQEEGKLVEEKKKLAEEEEALAWQREKLSEEETKLAQEEELLIQEKEKLAQHKEKMPEE 1794 Query: 60 E-----KVRQQIRDKYGLKKKEEK 78 E K Q I K L +K E+ Sbjct: 1795 EERLGRKREQLIEKKMKLAQKRER 1818 >gi|239754909 PREDICTED: hypothetical protein [Homo sapiens] Length = 245 Score = 49.3 bits (116), Expect = 9e-07 Identities = 27/93 (29%), Positives = 52/93 (55%), Gaps = 5/93 (5%) Query: 22 GEEEKDPDAQKKEEERQEALRQQEEERKAKHARMEAEREKVRQQIRDKYGLKKKEEKEAE 81 G++E++ + +K+ ER++ R++E+ERK + + E + E+ +++ K ++KE KE E Sbjct: 51 GKKERESERKKERREREKRKREREKERKRERGKKEKKGERKKEERERKKRRREKENKEGE 110 Query: 82 EKAALEQPCEGSLTRPKKAIPAGCGDEEEEEEE 114 EK ++ + R K G E E +EE Sbjct: 111 EKEKRKKKEKKERGRTSKE-----GKERERKEE 138 Score = 43.9 bits (102), Expect = 4e-05 Identities = 27/99 (27%), Positives = 52/99 (52%), Gaps = 6/99 (6%) Query: 22 GEEEKDPDAQKKEEERQEALRQ------QEEERKAKHARMEAEREKVRQQIRDKYGLKKK 75 G++EK + +K+E ER++ R+ +E+E++ K + E R + R++ +K+ Sbjct: 82 GKKEKKGERKKEERERKKRRREKENKEGEEKEKRKKKEKKERGRTSKEGKERERKEERKR 141 Query: 76 EEKEAEEKAALEQPCEGSLTRPKKAIPAGCGDEEEEEEE 114 EE++ E+ E+ E KK G++EEE +E Sbjct: 142 EERKERERKKEEREKERERKERKKRERKQVGEKEEERKE 180 Score = 40.8 bits (94), Expect = 3e-04 Identities = 23/70 (32%), Positives = 41/70 (58%), Gaps = 6/70 (8%) Query: 14 KDMGKMLGGEEEKDPDAQKKEEERQEALRQQEEERKAKHARMEAEREKVRQQIRDKYGLK 73 K+ G+ +E++ ++K EER+E R++EE K E ER++ +++ R + G K Sbjct: 121 KERGRTSKEGKERERKEERKREERKERERKKEEREK------ERERKERKKRERKQVGEK 174 Query: 74 KKEEKEAEEK 83 ++E KE E K Sbjct: 175 EEERKEKERK 184 Score = 40.4 bits (93), Expect = 4e-04 Identities = 24/94 (25%), Positives = 50/94 (53%), Gaps = 2/94 (2%) Query: 23 EEEKDPDAQKKEEERQEALR--QQEEERKAKHARMEAEREKVRQQIRDKYGLKKKEEKEA 80 +EE++ + ++KE +++E + ++EEERK K + +RE+ R++ + + K++ E++ Sbjct: 151 KEEREKERERKERKKRERKQVGEKEEERKEKERKERKKRERNRKERKKERERKERRERKK 210 Query: 81 EEKAALEQPCEGSLTRPKKAIPAGCGDEEEEEEE 114 E K E+ E R G E +E + Sbjct: 211 ERKKKEERKKERQKDRQTNWREKERGKRERKERK 244 Score = 39.7 bits (91), Expect = 7e-04 Identities = 24/80 (30%), Positives = 47/80 (58%), Gaps = 6/80 (7%) Query: 23 EEEKDPDAQKKEEERQEALRQQEEERKAKHARMEAEREKVRQQIR---DKYGLKKKEEKE 79 E E++ + +K+ ++ +E+ R++E + K R EREK R++ R +K G +KKEE+E Sbjct: 40 EREREIETRKEGKKERESERKKERREREKRKR---EREKERKRERGKKEKKGERKKEERE 96 Query: 80 AEEKAALEQPCEGSLTRPKK 99 +++ ++ EG +K Sbjct: 97 RKKRRREKENKEGEEKEKRK 116 Score = 39.3 bits (90), Expect = 0.001 Identities = 28/97 (28%), Positives = 48/97 (49%), Gaps = 9/97 (9%) Query: 11 GATKDMGKMLGGEEEKDPDAQKKEEERQEALRQQEEERKAKHARM--------EAEREKV 62 G T GK +EE+ + ++KE ER++ R++E ERK + R E +EK Sbjct: 124 GRTSKEGKERERKEERKRE-ERKERERKKEEREKERERKERKKRERKQVGEKEEERKEKE 182 Query: 63 RQQIRDKYGLKKKEEKEAEEKAALEQPCEGSLTRPKK 99 R++ + + +K+ +KE E K E+ E +K Sbjct: 183 RKERKKRERNRKERKKERERKERRERKKERKKKEERK 219 Score = 35.8 bits (81), Expect = 0.011 Identities = 15/66 (22%), Positives = 40/66 (60%) Query: 18 KMLGGEEEKDPDAQKKEEERQEALRQQEEERKAKHARMEAEREKVRQQIRDKYGLKKKEE 77 K +G +EE+ + ++KE +++E R++ ++ + + R E ++E+ +++ R K K ++ Sbjct: 169 KQVGEKEEERKEKERKERKKRERNRKERKKERERKERRERKKERKKKEERKKERQKDRQT 228 Query: 78 KEAEEK 83 E++ Sbjct: 229 NWREKE 234 Score = 31.6 bits (70), Expect = 0.20 Identities = 21/74 (28%), Positives = 39/74 (52%), Gaps = 5/74 (6%) Query: 14 KDMGKMLGGEEEKDPDAQKKEE----ERQEALRQQEEERKAKHARMEAEREKVRQQIRDK 69 K +G+ +EK+ +KK E ER++ ++E + K + + ER+K RQ+ R + Sbjct: 169 KQVGEKEEERKEKERKERKKRERNRKERKKERERKERRERKKERKKKEERKKERQKDR-Q 227 Query: 70 YGLKKKEEKEAEEK 83 ++KE + E K Sbjct: 228 TNWREKERGKRERK 241 Score = 28.9 bits (63), Expect = 1.3 Identities = 13/56 (23%), Positives = 31/56 (55%) Query: 28 PDAQKKEEERQEALRQQEEERKAKHARMEAEREKVRQQIRDKYGLKKKEEKEAEEK 83 P Q + ER+ + ++E +K + + + ER + ++ R++ +K+E + E+K Sbjct: 32 PGWQSEIREREREIETRKEGKKERESERKKERREREKRKREREKERKRERGKKEKK 87 >gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-like [Homo sapiens] Length = 828 Score = 48.9 bits (115), Expect = 1e-06 Identities = 29/106 (27%), Positives = 57/106 (53%), Gaps = 1/106 (0%) Query: 14 KDMGKMLGGEEEKDPDAQKKEEERQEALRQQEEERKAKHARMEAEREKVRQQIRDKYGLK 73 ++ +M+ +EEK + ++K E++E +R+QEE+ + + +M+ + EK+R+Q G + Sbjct: 628 QEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKMREQEEKMQGQE 687 Query: 74 KKEEKEAEEKAALEQPCEGSLTRPKKAIPAGCGDEE-EEEEESILD 118 +K ++ E+ E+ G + G EE E+EE I D Sbjct: 688 EKMREQEEKMRGQEEKMWGQEEKMWGQEEKMWGQEEMREKEERIRD 733 Score = 40.0 bits (92), Expect = 6e-04 Identities = 23/94 (24%), Positives = 54/94 (57%), Gaps = 3/94 (3%) Query: 23 EEEKDPDAQKKEEERQEALRQQEEERKAKHARMEAEREKVRQQIRDKYGLKKKEEKEAEE 82 EEE+ + +KK E +E +R+QEE+ + + +M + EK+ +Q + ++++EEK E+ Sbjct: 558 EEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQ---EEKMQEQEEKMWEQ 614 Query: 83 KAALEQPCEGSLTRPKKAIPAGCGDEEEEEEESI 116 + + + E + ++ + ++ +E+EE + Sbjct: 615 EEKMWEQEEEDKMQEQEEMMWEQEEKMQEQEEKM 648 Score = 39.7 bits (91), Expect = 7e-04 Identities = 22/66 (33%), Positives = 39/66 (59%), Gaps = 2/66 (3%) Query: 23 EEEKDPDAQKKEEERQEALRQQEEERKAKHARMEAEREKVRQQIRDKYGLKKKEEKEAEE 82 E+EK+ Q+KE Q+ LR+QEE+ + + +M + EK+R+Q + +++E +E Sbjct: 287 EQEKELREQEKELREQKKLREQEEQMQEQEEKMWEQEEKMREQEEKMW--RQEERLWEQE 344 Query: 83 KAALEQ 88 K EQ Sbjct: 345 KQMREQ 350 Score = 39.7 bits (91), Expect = 7e-04 Identities = 18/75 (24%), Positives = 45/75 (60%) Query: 14 KDMGKMLGGEEEKDPDAQKKEEERQEALRQQEEERKAKHARMEAEREKVRQQIRDKYGLK 73 ++ K + EEE + ++K +E++E +R+QEE+ + +M+ + EK+ +Q + + Sbjct: 563 REREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEKMWEQE 622 Query: 74 KKEEKEAEEKAALEQ 88 ++++ + +E+ EQ Sbjct: 623 EEDKMQEQEEMMWEQ 637 Score = 38.9 bits (89), Expect = 0.001 Identities = 23/69 (33%), Positives = 39/69 (56%), Gaps = 3/69 (4%) Query: 23 EEEKDPDAQKKEEERQEALRQQEEERKAKHARMEAEREKVRQQIR---DKYGLKKKEEKE 79 EEE+ + +KK E +E +R+QEE+ + + M + EK QQ R K L ++E+ + Sbjct: 390 EEERIREREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQ 449 Query: 80 AEEKAALEQ 88 +E+ EQ Sbjct: 450 EQEEKIWEQ 458 Score = 38.5 bits (88), Expect = 0.002 Identities = 25/104 (24%), Positives = 55/104 (52%), Gaps = 3/104 (2%) Query: 13 TKDMGKMLGGEEEKDPDAQKKEEERQEALRQQEEERKAKHARMEAEREKVRQQ---IRDK 69 T + + + +EE+ + +KK +++E + +QEE + + +M + EK+R+Q +R++ Sbjct: 229 TNTLQEEMWRQEEELREQEKKIRKQEEKMWRQEERLREQEGKMREQEEKMRRQEKRLREQ 288 Query: 70 YGLKKKEEKEAEEKAALEQPCEGSLTRPKKAIPAGCGDEEEEEE 113 +++EKE E+ L + E + +K E+EE+ Sbjct: 289 EKELREQEKELREQKKLREQEEQMQEQEEKMWEQEEKMREQEEK 332 Score = 38.5 bits (88), Expect = 0.002 Identities = 19/69 (27%), Positives = 41/69 (59%), Gaps = 3/69 (4%) Query: 23 EEEKDPDAQKKEE---ERQEALRQQEEERKAKHARMEAEREKVRQQIRDKYGLKKKEEKE 79 E+E++ Q++EE E++E +++QEE+ + +M + EK+R+Q G ++K ++ Sbjct: 620 EQEEEDKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKMREQ 679 Query: 80 AEEKAALEQ 88 E+ E+ Sbjct: 680 EEKMQGQEE 688 Score = 37.7 bits (86), Expect = 0.003 Identities = 19/61 (31%), Positives = 39/61 (63%), Gaps = 1/61 (1%) Query: 23 EEEKDPDAQKKEEERQEALRQQEEERKAKHARMEAEREKVRQQIRDKYGLKKKEEKEAEE 82 E+EK+ QKK E++E +++QEE+ + +M + EK+ +Q ++ ++K+ +E E+ Sbjct: 294 EQEKELREQKKLREQEEQMQEQEEKMWEQEEKMREQEEKMWRQ-EERLWEQEKQMREQEQ 352 Query: 83 K 83 K Sbjct: 353 K 353 Score = 37.7 bits (86), Expect = 0.003 Identities = 24/96 (25%), Positives = 53/96 (55%), Gaps = 5/96 (5%) Query: 23 EEEKDPDAQKKEEERQEALRQQEEERKAKHARMEAEREKVRQQ----IRDKYGLKKKEEK 78 EE+K + +KK +++E +R++E R+ + +M E E +R+Q + ++++EEK Sbjct: 538 EEKKTQEQEKKTWDQEEKMREEERMRE-REKKMREEEEMMREQEEKMQEQEEKMREQEEK 596 Query: 79 EAEEKAALEQPCEGSLTRPKKAIPAGCGDEEEEEEE 114 E++ +++ E + +K D+ +E+EE Sbjct: 597 MWEQEEKMQEQEEKMWEQEEKMWEQEEEDKMQEQEE 632 Score = 37.7 bits (86), Expect = 0.003 Identities = 20/71 (28%), Positives = 45/71 (63%), Gaps = 2/71 (2%) Query: 13 TKDMGKMLGGEEEKDPDAQKKEEERQEALRQQEEERKAKHARMEAEREKVRQQIRDKYGL 72 T++ K +EEK + +++ ER++ +R++EE + + +M+ + EK+R+Q +K Sbjct: 542 TQEQEKKTWDQEEKMRE-EERMREREKKMREEEEMMREQEEKMQEQEEKMREQ-EEKMWE 599 Query: 73 KKKEEKEAEEK 83 ++++ +E EEK Sbjct: 600 QEEKMQEQEEK 610 Score = 37.0 bits (84), Expect = 0.005 Identities = 24/98 (24%), Positives = 49/98 (50%), Gaps = 1/98 (1%) Query: 18 KMLGGEEEKDPDAQKKEEERQEALRQQEEERKAKHARMEAEREKVRQQIRDKYGLKKKEE 77 KM EE+ +K E+ ++ Q+EE++ + M E+E+ Q+ +K ++++ Sbjct: 596 KMWEQEEKMQEQEEKMWEQEEKMWEQEEEDKMQEQEEMMWEQEEKMQEQEEKMWEQEEKM 655 Query: 78 KEAEEK-AALEQPCEGSLTRPKKAIPAGCGDEEEEEEE 114 +E EEK E+ +G + ++ G EE+ E+ Sbjct: 656 REQEEKMREQEEKMQGQEEKMREQEEKMQGQEEKMREQ 693 Score = 36.2 bits (82), Expect = 0.008 Identities = 24/83 (28%), Positives = 47/83 (56%), Gaps = 8/83 (9%) Query: 14 KDMGKMLGGE-----EEKDPDAQKKEEERQEALRQQEEERKAKHARMEAEREKVR---QQ 65 +D +M G E +EK + + + E++E +R QE++ + RM + E++R ++ Sbjct: 463 RDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMWEQDERLREKEER 522 Query: 66 IRDKYGLKKKEEKEAEEKAALEQ 88 +R++ + ++EEK EEK EQ Sbjct: 523 MREQKKMWQQEEKMREEKKTQEQ 545 Score = 35.8 bits (81), Expect = 0.011 Identities = 21/90 (23%), Positives = 48/90 (53%), Gaps = 2/90 (2%) Query: 23 EEEK--DPDAQKKEEERQEALRQQEEERKAKHARMEAEREKVRQQIRDKYGLKKKEEKEA 80 +EEK + + + K +E++E + +QEE+ + + +M + EK+R+Q ++K + + Sbjct: 614 QEEKMWEQEEEDKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQE 673 Query: 81 EEKAALEQPCEGSLTRPKKAIPAGCGDEEE 110 E+ E+ +G + ++ G EE+ Sbjct: 674 EKMREQEEKMQGQEEKMREQEEKMRGQEEK 703 Score = 35.4 bits (80), Expect = 0.014 Identities = 23/82 (28%), Positives = 47/82 (57%), Gaps = 11/82 (13%) Query: 18 KMLGGEEEKDPDAQKKEEERQEALRQQEEERKAKHARMEAEREKVRQQ---IRDK----- 69 K L +EE+ + ++K E++E +R+QEE+ + R+ + +++R+Q +RD+ Sbjct: 303 KKLREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEERMW 362 Query: 70 ---YGLKKKEEKEAEEKAALEQ 88 L++KEE+ E++ EQ Sbjct: 363 EQDERLREKEERMREQEKMWEQ 384 Score = 35.4 bits (80), Expect = 0.014 Identities = 20/67 (29%), Positives = 40/67 (59%), Gaps = 1/67 (1%) Query: 18 KMLGGEEEKDPDAQKKEEERQEALRQQEEERKAKHARMEAEREKV-RQQIRDKYGLKKKE 76 +M+ +EEK + ++K E++E + +QEE+ + + +M + EK+ Q+ DK +++ Sbjct: 574 EMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEEDKMQEQEEM 633 Query: 77 EKEAEEK 83 E EEK Sbjct: 634 MWEQEEK 640 Score = 34.3 bits (77), Expect = 0.031 Identities = 19/71 (26%), Positives = 43/71 (60%), Gaps = 5/71 (7%) Query: 18 KMLGGEEEKDPDAQKKEEERQEALRQQEEERKAKHARMEAEREKVRQQIRDKYGLKKKEE 77 K + +E+K D +++ E+ E LR ++EER + +M + EK++++ R ++++E+ Sbjct: 345 KQMREQEQKMRDQEERMWEQDERLR-EKEERMREQEKMWEQEEKMQEEER----IREREK 399 Query: 78 KEAEEKAALEQ 88 K EE+ + + Sbjct: 400 KMREEEETMRE 410 Score = 34.3 bits (77), Expect = 0.031 Identities = 16/66 (24%), Positives = 41/66 (62%) Query: 23 EEEKDPDAQKKEEERQEALRQQEEERKAKHARMEAEREKVRQQIRDKYGLKKKEEKEAEE 82 +EEK + ++K E++E +++QEE+ + +M + E+ + Q +++ +++E+ + +E Sbjct: 586 QEEKMREQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEEDKMQEQEEMMWEQEEKMQEQE 645 Query: 83 KAALEQ 88 + EQ Sbjct: 646 EKMWEQ 651 Score = 33.9 bits (76), Expect = 0.040 Identities = 20/78 (25%), Positives = 43/78 (55%), Gaps = 7/78 (8%) Query: 18 KMLGGEE---EKDPDAQKKEEERQEALRQQEEERKAKHARMEAEREK----VRQQIRDKY 70 KM EE E+D ++KEE +E + ++E K + + E+EK +++R++ Sbjct: 501 KMWDQEERMWEQDERLREKEERMREQKKMWQQEEKMREEKKTQEQEKKTWDQEEKMREEE 560 Query: 71 GLKKKEEKEAEEKAALEQ 88 ++++E+K EE+ + + Sbjct: 561 RMREREKKMREEEEMMRE 578 Score = 33.9 bits (76), Expect = 0.040 Identities = 17/77 (22%), Positives = 40/77 (51%) Query: 14 KDMGKMLGGEEEKDPDAQKKEEERQEALRQQEEERKAKHARMEAEREKVRQQIRDKYGLK 73 ++ + + G+EEK + ++K ++E + QEE+ + +M + E ++ R + + Sbjct: 677 REQEEKMQGQEEKMREQEEKMRGQEEKMWGQEEKMWGQEEKMWGQEEMREKEERIRDQKE 736 Query: 74 KKEEKEAEEKAALEQPC 90 K +E+ E + +PC Sbjct: 737 KMQERLPEHEERCSEPC 753 Score = 33.5 bits (75), Expect = 0.052 Identities = 18/66 (27%), Positives = 39/66 (59%), Gaps = 4/66 (6%) Query: 23 EEEKDPDAQKKEEERQEALRQQEEERKAKHARMEAEREKVRQQIRDKYGLKKKEEKEAEE 82 +EE+ + +K+ E+++ +R QEE + R+ + E++R+Q + + ++EEK EE Sbjct: 336 QEERLWEQEKQMREQEQKMRDQEERMWEQDERLREKEERMREQEK----MWEQEEKMQEE 391 Query: 83 KAALEQ 88 + E+ Sbjct: 392 ERIRER 397 Score = 32.7 bits (73), Expect = 0.089 Identities = 22/75 (29%), Positives = 40/75 (53%), Gaps = 9/75 (12%) Query: 23 EEEKDPD-----AQKKEEERQEALRQQEEERKAKHARMEAEREKVRQQIRDKY----GLK 73 +EEK D Q+K+ RQE +R+QE++ + +M + +K+ Q + L+ Sbjct: 458 QEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMWEQDERLR 517 Query: 74 KKEEKEAEEKAALEQ 88 +KEE+ E+K +Q Sbjct: 518 EKEERMREQKKMWQQ 532 Score = 32.0 bits (71), Expect = 0.15 Identities = 19/63 (30%), Positives = 40/63 (63%), Gaps = 6/63 (9%) Query: 23 EEEKDPDAQKKEEERQEALRQQEEERKAKHARMEAEREKVRQQIRDKYGLKKKEEK--EA 80 EEE+ Q+++ ++QE ++EE++ + R+ ++EK+ +Q + ++++EEK E Sbjct: 403 EEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEK----MQEQEEKIWEQ 458 Query: 81 EEK 83 EEK Sbjct: 459 EEK 461 Score = 31.6 bits (70), Expect = 0.20 Identities = 16/69 (23%), Positives = 40/69 (57%), Gaps = 3/69 (4%) Query: 23 EEEKDPDAQKKEEERQEALRQQEEERKAKHARMEAEREKVRQQIRDKY---GLKKKEEKE 79 E+E+ +++ ER++ +R++EE + + +M+ + E + +Q ++ L +++EK Sbjct: 383 EQEEKMQEEERIREREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKL 442 Query: 80 AEEKAALEQ 88 E++ EQ Sbjct: 443 WEQEKMQEQ 451 Score = 30.8 bits (68), Expect = 0.34 Identities = 18/78 (23%), Positives = 46/78 (58%), Gaps = 3/78 (3%) Query: 14 KDMGKMLGGEEEKDPDAQKKEEERQEALRQQEE--ERKAKHARMEAEREKVRQQIRDKYG 71 ++ + + +EE+ + ++ E++E +R+QE+ E++ K E RE+ ++ ++ Sbjct: 348 REQEQKMRDQEERMWEQDERLREKEERMREQEKMWEQEEKMQEEERIREREKKMREEEET 407 Query: 72 LKKKEEK-EAEEKAALEQ 88 ++++EEK + +E+ EQ Sbjct: 408 MREQEEKMQKQEENMWEQ 425 Score = 30.8 bits (68), Expect = 0.34 Identities = 25/86 (29%), Positives = 42/86 (48%), Gaps = 15/86 (17%) Query: 18 KMLGGEE---EKDPDAQKKEEE--------RQEALRQQEEERKAKHARMEAEREKVRQQ- 65 KM EE E+D ++KEE QE Q+EE + + +M E E +R+Q Sbjct: 353 KMRDQEERMWEQDERLREKEERMREQEKMWEQEEKMQEEERIREREKKMREEEETMREQE 412 Query: 66 ---IRDKYGLKKKEEKEAEEKAALEQ 88 + + + ++EEKE +++ EQ Sbjct: 413 EKMQKQEENMWEQEEKEWQQQRLPEQ 438 Score = 30.4 bits (67), Expect = 0.44 Identities = 23/94 (24%), Positives = 51/94 (54%), Gaps = 4/94 (4%) Query: 23 EEEKDPDAQKKEEERQEALRQQ---EEERKAKHARMEAEREKVRQQIRDKYGLKKKEEKE 79 E+E+ QKK +++E +R++ +E+ K + E RE+ R + R+K ++++EE Sbjct: 518 EKEERMREQKKMWQQEEKMREEKKTQEQEKKTWDQEEKMREEERMREREK-KMREEEEMM 576 Query: 80 AEEKAALEQPCEGSLTRPKKAIPAGCGDEEEEEE 113 E++ +++ E + +K +E+EE+ Sbjct: 577 REQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEK 610 Score = 29.6 bits (65), Expect = 0.76 Identities = 18/58 (31%), Positives = 33/58 (56%), Gaps = 2/58 (3%) Query: 23 EEEKDPDAQKKEEERQEALRQQEE--ERKAKHARMEAEREKVRQQIRDKYGLKKKEEK 78 E+EK + ++K E++E +R QEE ++ K R E RE+ Q + ++ +E+K Sbjct: 444 EQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQK 501 Score = 26.6 bits (57), Expect = 6.4 Identities = 22/75 (29%), Positives = 40/75 (53%), Gaps = 11/75 (14%) Query: 25 EKDPDAQKKEE-----ERQEALRQQEEERKAK---HARMEAEREKVRQQ---IRDKYGLK 73 E++ QK+EE E +E +Q+ E+K K +M+ + EK+ +Q IRD+ + Sbjct: 410 EQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMW 469 Query: 74 KKEEKEAEEKAALEQ 88 +E+K ++ EQ Sbjct: 470 GQEKKMWRQEKMREQ 484 Score = 26.2 bits (56), Expect = 8.4 Identities = 12/43 (27%), Positives = 20/43 (46%) Query: 23 EEEKDPDAQKKEEERQEALRQQEEERKAKHARMEAEREKVRQQ 65 +++K + E E E+E+KA H EA R ++ Q Sbjct: 48 KKKKINNGTNPETTTSEGCHSPEDEKKASHQHQEALRREIEAQ 90 >gi|148746195 trichohyalin [Homo sapiens] Length = 1943 Score = 47.4 bits (111), Expect = 4e-06 Identities = 23/68 (33%), Positives = 43/68 (63%), Gaps = 2/68 (2%) Query: 23 EEEKDPDAQKKEEER--QEALRQQEEERKAKHARMEAEREKVRQQIRDKYGLKKKEEKEA 80 EE ++ ++++EER Q+ R+QEEER+ + R E E E+ QQ+R + L+++++ Sbjct: 332 EERREQQLRREQEERREQQLRREQEEERREQQLRREQEEERREQQLRREQQLRREQQLRR 391 Query: 81 EEKAALEQ 88 E++ EQ Sbjct: 392 EQQLRREQ 399 Score = 45.4 bits (106), Expect = 1e-05 Identities = 23/73 (31%), Positives = 44/73 (60%), Gaps = 6/73 (8%) Query: 30 AQKKEEERQEALRQQEEERKAKHARMEAEREKVRQQIRDKYGLKKKEEKEAEEKAALEQP 89 ++++EE RQ+ LR++++ER+ + + E E E++ Q+ LK++ E+E E+ E+ Sbjct: 636 SEEQEERRQQQLRREQQERREQRLKREEEEERLEQR------LKREHEEERREQELAEEE 689 Query: 90 CEGSLTRPKKAIP 102 E + R K IP Sbjct: 690 QEQARERIKSRIP 702 Score = 43.5 bits (101), Expect = 5e-05 Identities = 18/69 (26%), Positives = 47/69 (68%), Gaps = 6/69 (8%) Query: 26 KDPDAQKKEEERQEALRQQEEERKAKHARMEAEREKVRQQIRDKYGLKKKEEK------E 79 ++ + ++++E R++ LR+++EER+ + + + E E+++Q++R + L++++E+ + Sbjct: 492 EEEERREQQERREQQLRREQEERREQRLKRQEEEERLQQRLRSEQQLRREQEERREQLLK 551 Query: 80 AEEKAALEQ 88 EE+ LEQ Sbjct: 552 REEEKRLEQ 560 Score = 43.1 bits (100), Expect = 7e-05 Identities = 21/64 (32%), Positives = 40/64 (62%), Gaps = 5/64 (7%) Query: 25 EKDPDAQKKEEERQEALRQQEEERKAKHARMEAEREKVRQQIRDKYGLKKKEEKEAEEKA 84 E+ +++EE R++ LR+++EER+ + R E E E+ QQ+R +++EE+ E++ Sbjct: 323 EQQERREQQEERREQQLRREQEERREQQLRREQEEERREQQLR-----REQEEERREQQL 377 Query: 85 ALEQ 88 EQ Sbjct: 378 RREQ 381 Score = 42.0 bits (97), Expect = 1e-04 Identities = 33/115 (28%), Positives = 58/115 (50%), Gaps = 5/115 (4%) Query: 6 KQALGGATKDMGKMLGGEEEKDPDAQKKEEERQEALRQQEEERKAKHAR---MEAEREKV 62 K AL + ++L EEE+ ++++ RQE RQ EE + + + EREK Sbjct: 892 KPALQEQLRKEQQLLQEEEEELQREEREKRRRQEQERQYREEEQLQQEEEQLLREEREKR 951 Query: 63 RQQIRDKYGLKKKEEKEAEEKAALEQPCEGSLTRPKKAIPAGCGDEEEEEEESIL 117 R+Q R++ K K+ ++ EE+ E+P + +K +E ++EEE +L Sbjct: 952 RRQERERQYRKDKKLQQKEEQLLGEEPEKRRRQEREKKYRE--EEELQQEEEQLL 1004 Score = 41.2 bits (95), Expect = 3e-04 Identities = 25/95 (26%), Positives = 52/95 (54%), Gaps = 3/95 (3%) Query: 23 EEEKDPDAQKKEEERQEALRQQEEERKAKHARMEAEREKVRQQIRDKYGLKKKEEKEAEE 82 + E++ + ++E +Q+ R QEEER+ + ++E E E+ QQ R + L++++E+ E+ Sbjct: 459 KREEETERHEQERRKQQLKRDQEEERRERWLKLE-EEERREQQERREQQLRREQEERREQ 517 Query: 83 KAALEQPCEGSLTRPKKAIPAGCGDEEEEEEESIL 117 + L++ E + + E+EE E +L Sbjct: 518 R--LKRQEEEERLQQRLRSEQQLRREQEERREQLL 550 Score = 41.2 bits (95), Expect = 3e-04 Identities = 24/74 (32%), Positives = 44/74 (59%), Gaps = 3/74 (4%) Query: 18 KMLGGEEEKDPDAQKKEEERQEALRQQEEERKAKHARMEAEREKVRQQIRDKYGLKKKEE 77 ++LG E EK +++++ R+E QQEEE+ + R + R++ +Q R K L+++EE Sbjct: 972 QLLGEEPEKRRRQEREKKYREEEELQQEEEQLLREEREKRRRQEWERQYRKKDELQQEEE 1031 Query: 78 ---KEAEEKAALEQ 88 +E EK L++ Sbjct: 1032 QLLREEREKRRLQE 1045 Score = 40.4 bits (93), Expect = 4e-04 Identities = 27/100 (27%), Positives = 57/100 (57%), Gaps = 9/100 (9%) Query: 23 EEE---KDPDAQKKEEERQEALRQQEEERKAKHARMEAEREKVRQQIRDKYGLKKKEEKE 79 EEE ++ +++ +ER+ R++EE ++ + + EREK R+Q ++ +++E ++ Sbjct: 1089 EEEQLLREEPEKRRRQERERQCREEEELQQEEEQLLREEREKRRRQELERQYREEEEVQQ 1148 Query: 80 AEEKAALEQPCEGSLTRPKKAIPAGCGDEEE--EEEESIL 117 EE+ E+P + R ++ + +EEE +EEE +L Sbjct: 1149 EEEQLLREEPEK----RRRQELERQYREEEELQQEEEQLL 1184 Score = 40.0 bits (92), Expect = 6e-04 Identities = 22/66 (33%), Positives = 39/66 (59%), Gaps = 1/66 (1%) Query: 18 KMLGGEEEKDPDAQKKEEERQEALRQQEEERKAKHARMEAEREKVRQQIRDKYGLKKKEE 77 + L E+E++ QK E+ER+E ++E+E + + E E E+ +Q R K LK+ +E Sbjct: 423 QQLRREQEEERHEQKHEQERREQRLKREQEERRDWLKREEETER-HEQERRKQQLKRDQE 481 Query: 78 KEAEEK 83 +E E+ Sbjct: 482 EERRER 487 Score = 39.7 bits (91), Expect = 7e-04 Identities = 23/95 (24%), Positives = 55/95 (57%), Gaps = 7/95 (7%) Query: 23 EEEKDPDAQKKEEERQEALRQQEEERKAKHARMEAEREKVRQQIRDKYGLKKKEEKEAEE 82 +E ++ ++++EER++ L ++EEER+ + + E E E++ Q+++ + + ++E+ E+ Sbjct: 560 QERREQRLKREQEERRDQLLKREEERRQQRLKREQE-ERLEQRLKREEVERLEQEERREQ 618 Query: 83 KAALEQPCEGSLTRPKKAIPAGCGDEEEEEEESIL 117 + E+P E + K+ +E+EE + L Sbjct: 619 RLKREEPEEERRQQLLKS------EEQEERRQQQL 647 Score = 39.7 bits (91), Expect = 7e-04 Identities = 31/102 (30%), Positives = 55/102 (53%), Gaps = 8/102 (7%) Query: 23 EEEKDPDAQKKEEERQEALRQQEEERKAKHARMEAEREKVRQQIRDKYGLKKKEEKEAEE 82 EE + + Q EER++ RQ+ E + K ++ E E++ ++ R+K L+++E + EE Sbjct: 994 EELQQEEEQLLREEREKRRRQEWERQYRKKDELQQEEEQLLREEREKRRLQERERQYREE 1053 Query: 83 KAALEQPCEGSL-----TRPKKAIPAGCGDEEE--EEEESIL 117 + L+Q E L TR ++ + EEE +EEE +L Sbjct: 1054 E-ELQQEEEQLLGEERETRRRQELERQYRKEEELQQEEEQLL 1094 Score = 39.7 bits (91), Expect = 7e-04 Identities = 31/102 (30%), Positives = 52/102 (50%), Gaps = 11/102 (10%) Query: 18 KMLGGEEEKDPDAQKKEEERQEALRQQEEERKAKHARMEAEREKVRQQIRDKYGLKKKEE 77 ++L E EK +++ + R+E QQEEE+ R R+++ +Q R K+EE Sbjct: 1032 QLLREEREKRRLQERERQYREEEELQQEEEQLLGEERETRRRQELERQYR------KEEE 1085 Query: 78 KEAEEKAALEQPCEGSLTRPKKAIPAGCGDEEE--EEEESIL 117 + EE+ L + E R ++ C +EEE +EEE +L Sbjct: 1086 LQQEEEQLLREEPE---KRRRQERERQCREEEELQQEEEQLL 1124 Score = 39.3 bits (90), Expect = 0.001 Identities = 23/94 (24%), Positives = 49/94 (52%), Gaps = 7/94 (7%) Query: 24 EEKDPDAQKKEEERQEALRQQEEERKAKHARMEAEREKVRQQIRDKYGLKKKEEKEAEEK 83 +E++ Q+ E+Q +Q+EE R+ + R E + + +Q+ R + L++++E+ E++ Sbjct: 291 QEEEQQQQRLRREQQLRRKQEEERREQQEERREQQERREQQEERREQQLRREQEERREQQ 350 Query: 84 AALEQPCEGSLTRPKKAIPAGCGDEEEEEEESIL 117 EQ E + ++ ++EEE E L Sbjct: 351 LRREQEEERREQQLRR-------EQEEERREQQL 377 Score = 38.9 bits (89), Expect = 0.001 Identities = 24/86 (27%), Positives = 50/86 (58%), Gaps = 4/86 (4%) Query: 31 QKKEEERQEALRQQEEERKAKHARMEAEREKVRQQIRDKYGLKKKEEKEAEEKAALEQPC 90 ++++EER+E L ++EEE++ + R E ++ +++ RD+ L K+EE+ +++ EQ Sbjct: 539 RREQEERREQLLKREEEKRLEQERREQRLKREQEERRDQ--LLKREEERRQQRLKREQ-- 594 Query: 91 EGSLTRPKKAIPAGCGDEEEEEEESI 116 E L + K ++EE E+ + Sbjct: 595 EERLEQRLKREEVERLEQEERREQRL 620 Score = 38.5 bits (88), Expect = 0.002 Identities = 20/63 (31%), Positives = 41/63 (65%), Gaps = 3/63 (4%) Query: 23 EEEKDPDAQKKEEERQE--ALRQQEEERKAKHARMEAEREKVRQQIRDKYGLKKKEEKEA 80 +E ++ ++++EER+E RQ+EEER + R E + + +++ R++ LK++EEK Sbjct: 500 QERREQQLRREQEERREQRLKRQEEEERLQQRLRSEQQLRREQEERREQL-LKREEEKRL 558 Query: 81 EEK 83 E++ Sbjct: 559 EQE 561 Score = 38.5 bits (88), Expect = 0.002 Identities = 30/97 (30%), Positives = 52/97 (53%), Gaps = 7/97 (7%) Query: 23 EEEKDPDAQKKEEE-RQEALRQQEEERKAKHARMEAEREKVRQQIRDKYGLKKKEEKEAE 81 +EE+ K+EEE RQ+ L++++EER + + E E E++ Q+ R + LK++E +E Sbjct: 571 QEERRDQLLKREEERRQQRLKREQEERLEQRLKRE-EVERLEQEERREQRLKREEPEEER 629 Query: 82 EKAAL-----EQPCEGSLTRPKKAIPAGCGDEEEEEE 113 + L E+ + L R ++ EEEEE Sbjct: 630 RQQLLKSEEQEERRQQQLRREQQERREQRLKREEEEE 666 Score = 38.5 bits (88), Expect = 0.002 Identities = 23/109 (21%), Positives = 57/109 (52%), Gaps = 15/109 (13%) Query: 14 KDMGKMLGGEEEKDPDAQKKE--------EERQEALRQQEEERKAKHARMEAEREKVRQQ 65 +D+ +LG ++E+D + +++ E ++ R++++E K + + + E++ +R++ Sbjct: 1265 QDLQHLLGEQQERDREQERRRWQQRDRHFPEEEQLEREEQKEAKRRDRKSQEEKQLLREE 1324 Query: 66 IRDKYGLKKKEEKEAEEKAALEQPCEGSLTRPKKAIPAGCGDEEEEEEE 114 +K ++ + K EE+ L++ E L R ++ D + EEE Sbjct: 1325 REEKRRRQETDRKFREEEQLLQEREEQPLRRQER-------DRKFREEE 1366 Score = 38.1 bits (87), Expect = 0.002 Identities = 22/71 (30%), Positives = 42/71 (59%), Gaps = 6/71 (8%) Query: 18 KMLGGEEEKDPDAQKKEEERQEALRQQEEERKAKHARMEAEREKVRQQIRDKYGLKKKEE 77 + L ++E++ Q++E Q+ R+Q+EER+ + R E E E+ QQ+R +++EE Sbjct: 304 QQLRRKQEEERREQQEERREQQERREQQEERREQQLRREQE-ERREQQLR-----REQEE 357 Query: 78 KEAEEKAALEQ 88 + E++ EQ Sbjct: 358 ERREQQLRREQ 368 Score = 37.4 bits (85), Expect = 0.004 Identities = 25/94 (26%), Positives = 52/94 (55%), Gaps = 6/94 (6%) Query: 24 EEKDPDAQKKEEERQEALRQQEEERKAKHARMEAEREKVRQQIRDKYGLKKKEEKEAEEK 83 EE++ Q++ E+Q R+QEE R+ + R E E E+++Q++R + L++++E+ E+ Sbjct: 492 EEEERREQQERREQQLR-REQEERREQRLKRQE-EEERLQQRLRSEQQLRREQEERREQL 549 Query: 84 AALEQPCEGSLTRPKKAIPAGCGDEEEEEEESIL 117 E+ R ++ + E+EE + +L Sbjct: 550 LKREEEKRLEQERREQRLKR----EQEERRDQLL 579 Score = 37.0 bits (84), Expect = 0.005 Identities = 16/66 (24%), Positives = 42/66 (63%) Query: 23 EEEKDPDAQKKEEERQEALRQQEEERKAKHARMEAEREKVRQQIRDKYGLKKKEEKEAEE 82 +E ++ ++++EER++ L+++EE + + R + + ++ +++ R + LK +EE+ E+ Sbjct: 440 QERREQRLKREQEERRDWLKREEETERHEQERRKQQLKRDQEEERRERWLKLEEEERREQ 499 Query: 83 KAALEQ 88 + EQ Sbjct: 500 QERREQ 505 Score = 36.6 bits (83), Expect = 0.006 Identities = 21/69 (30%), Positives = 43/69 (62%), Gaps = 4/69 (5%) Query: 23 EEEKDPDAQKKEEE--RQEALR-QQEEERKAKHARMEAEREKVRQQIRDKYGLKKKEEKE 79 EE ++ ++++EE R++ LR +QEEER+ + R E + + QQ+R + L+++++ Sbjct: 344 EERREQQLRREQEEERREQQLRREQEEERREQQLRREQQLRR-EQQLRREQQLRREQQLR 402 Query: 80 AEEKAALEQ 88 E++ EQ Sbjct: 403 REQQLRREQ 411 Score = 35.8 bits (81), Expect = 0.011 Identities = 24/103 (23%), Positives = 56/103 (54%), Gaps = 4/103 (3%) Query: 24 EEKDPDAQKKEEERQEALRQQE--EERKAKHARMEAEREKVRQQIRDKYGLKKKEE-KEA 80 + ++ + ++EE R++ L+++E EER+ + + E + E+ +QQ+R + ++++ K Sbjct: 603 KREEVERLEQEERREQRLKREEPEEERRQQLLKSEEQEERRQQQLRREQQERREQRLKRE 662 Query: 81 EEKAALEQPCEGSLTRPKKAIPAGCGDEEEEEEESILDTVLKY 123 EE+ LEQ + ++ +E+E+ E I + K+ Sbjct: 663 EEEERLEQRLKREHEEERREQEL-AEEEQEQARERIKSRIPKW 704 Score = 35.8 bits (81), Expect = 0.011 Identities = 31/102 (30%), Positives = 54/102 (52%), Gaps = 11/102 (10%) Query: 18 KMLGGEEEKDPDAQKKEEERQEALRQQEEERKAKHARMEAEREKVRQQIRDKYGLKKKEE 77 ++LG E E + + + R+E QQEEE+ + E EK R+Q R++ +++EE Sbjct: 1062 QLLGEERETRRRQELERQYRKEEELQQEEEQ-----LLREEPEKRRRQERERQ-CREEEE 1115 Query: 78 KEAEEKAALEQPCEGSLTRPKKAIPAGCGDEEE--EEEESIL 117 + EE+ L + E R ++ + +EEE +EEE +L Sbjct: 1116 LQQEEEQLLREERE---KRRRQELERQYREEEEVQQEEEQLL 1154 Score = 35.8 bits (81), Expect = 0.011 Identities = 20/62 (32%), Positives = 39/62 (62%), Gaps = 6/62 (9%) Query: 22 GEEEK----DPDAQKKEEERQEALRQQEEERKAKHARMEAEREKVRQQIRDKYGLKKKEE 77 GEE++ + D + +EEE+Q LR+QE ERK + R+++ ++ R++ L+++ E Sbjct: 1679 GEEQQLRRQERDRKFREEEQQ--LRRQERERKFLQEEQQLRRQELERKFREEEQLRQETE 1736 Query: 78 KE 79 +E Sbjct: 1737 QE 1738 Score = 35.4 bits (80), Expect = 0.014 Identities = 29/106 (27%), Positives = 56/106 (52%), Gaps = 8/106 (7%) Query: 14 KDMGKMLGGEEEKDPDAQKKEE-----ERQEALRQ-QEEERKAKHARMEAEREKVRQQIR 67 K+ K+ E ++ + Q++EE ERQE R+ QEEE++ + R E + + +++ R Sbjct: 255 KEEEKLQEEEPQRQRELQEEEEQLRKLERQELRRERQEEEQQQQRLRREQQLRRKQEEER 314 Query: 68 DKYGLKKKEEKEAEEKAALEQPCEGSLTRPKKAIPAGCGDEEEEEE 113 + +++E++E E+ E+ E L R ++ E+EEE Sbjct: 315 REQQEERREQQERREQQ--EERREQQLRREQEERREQQLRREQEEE 358 Score = 35.0 bits (79), Expect = 0.018 Identities = 24/97 (24%), Positives = 52/97 (53%), Gaps = 7/97 (7%) Query: 23 EEEKDPDAQKKEEE--RQEALRQQEEERKAKHARMEAEREKVRQ-----QIRDKYGLKKK 75 EEE+ ++E++ R++ LR++++ R+ + R E + + +Q Q+R + L+++ Sbjct: 369 EEERREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRRE 428 Query: 76 EEKEAEEKAALEQPCEGSLTRPKKAIPAGCGDEEEEE 112 +E+E E+ ++ E L R ++ EEE E Sbjct: 429 QEEERHEQKHEQERREQRLKREQEERRDWLKREEETE 465 Score = 35.0 bits (79), Expect = 0.018 Identities = 21/84 (25%), Positives = 39/84 (46%) Query: 31 QKKEEERQEALRQQEEERKAKHARMEAEREKVRQQIRDKYGLKKKEEKEAEEKAALEQPC 90 Q+ E+Q Q+EE + KH + E+ R+Q + LK++EE E E+ +Q Sbjct: 417 QQLRREQQLRREQEEERHEQKHEQERREQRLKREQEERRDWLKREEETERHEQERRKQQL 476 Query: 91 EGSLTRPKKAIPAGCGDEEEEEEE 114 + ++ +EE E++ Sbjct: 477 KRDQEEERRERWLKLEEEERREQQ 500 Score = 34.7 bits (78), Expect = 0.024 Identities = 21/74 (28%), Positives = 42/74 (56%), Gaps = 3/74 (4%) Query: 18 KMLGGEEEKDPDAQKKEEERQEALRQQEEERKAKHARMEAEREKVRQQIRDKYGLKKKEE 77 ++L E EK + + + R+E QQEEE+ + + R+++ +Q R++ L+++EE Sbjct: 1122 QLLREEREKRRRQELERQYREEEEVQQEEEQLLREEPEKRRRQELERQYREEEELQQEEE 1181 Query: 78 ---KEAEEKAALEQ 88 +E +EK E+ Sbjct: 1182 QLLREEQEKRRQER 1195 Score = 34.7 bits (78), Expect = 0.024 Identities = 21/63 (33%), Positives = 37/63 (58%), Gaps = 6/63 (9%) Query: 29 DAQKKEEERQEALRQQEEERK---AKHARMEAEREKVRQQIRDKYGLKKKEEKEAEEKAA 85 + Q ++E QE LR+QE RK + R E E +++R+Q RD+ K +EE++ ++ Sbjct: 1728 EEQLRQETEQEQLRRQERYRKILEEEQLRPEREEQQLRRQERDR---KFREEEQLRQERE 1784 Query: 86 LEQ 88 +Q Sbjct: 1785 EQQ 1787 Score = 34.3 bits (77), Expect = 0.031 Identities = 27/103 (26%), Positives = 48/103 (46%), Gaps = 14/103 (13%) Query: 22 GEEEKDPDAQKKEEERQEALRQQEEE----------RKAKHARMEAEREKVRQQIRDKYG 71 G EEK Q++ ERQ+ + Q+EEE RK + E E ++ R+ ++ Sbjct: 222 GREEK----QQQRRERQDRVFQEEEEKEWRKRETVLRKEEEKLQEEEPQRQRELQEEEEQ 277 Query: 72 LKKKEEKEAEEKAALEQPCEGSLTRPKKAIPAGCGDEEEEEEE 114 L+K E +E + E+ + L R ++ + E++EE Sbjct: 278 LRKLERQELRRERQEEEQQQQRLRREQQLRRKQEEERREQQEE 320 Score = 34.3 bits (77), Expect = 0.031 Identities = 30/103 (29%), Positives = 53/103 (51%), Gaps = 5/103 (4%) Query: 18 KMLGGEEEKDPDAQKKEEERQEALRQQEEERKAKHARMEA---EREKVRQQIRDKYGLKK 74 + L EEE+ ++++ RQE RQ +++K + + E EK R+Q R+K ++ Sbjct: 934 EQLQQEEEQLLREEREKRRRQERERQYRKDKKLQQKEEQLLGEEPEKRRRQEREK-KYRE 992 Query: 75 KEEKEAEEKAALEQPCEGSLTRPKKAIPAGCGDEEEEEEESIL 117 +EE + EE+ L + E R + DE ++EEE +L Sbjct: 993 EEELQQEEEQLLREERE-KRRRQEWERQYRKKDELQQEEEQLL 1034 Score = 34.3 bits (77), Expect = 0.031 Identities = 20/64 (31%), Positives = 37/64 (57%), Gaps = 4/64 (6%) Query: 29 DAQKKEEERQEALRQQEEERK---AKHARMEAEREKVRQQIRD-KYGLKKKEEKEAEEKA 84 + Q ++E ++ LR QE +RK + R E E +++R Q RD KY ++++ + E++ Sbjct: 1776 EEQLRQEREEQQLRSQESDRKFREEEQLRQEREEQQLRPQQRDGKYRWEEEQLQLEEQEQ 1835 Query: 85 ALEQ 88 L Q Sbjct: 1836 RLRQ 1839 Score = 33.9 bits (76), Expect = 0.040 Identities = 24/97 (24%), Positives = 51/97 (52%), Gaps = 10/97 (10%) Query: 23 EEEKDPDAQKKEEERQEALRQQEEERKAKHARMEAEREKVRQQI-RDKYGLKKKEEKEAE 81 EEE ++K +E++ L + EE+ + + + +R++ +++ R + +++EE+ AE Sbjct: 130 EEEPGQRRRQKRQEQERELAEGEEQSEKQERLEQRDRQRRDEELWRQRQEWQEREERRAE 189 Query: 82 EKAALEQPCEGSLTRPKKAIPAGCGDEEEEEEESILD 118 E+ Q C+G T + P DEE+ +L+ Sbjct: 190 EEQL--QSCKGHET---EEFP----DEEQLRRRELLE 217 Score = 33.9 bits (76), Expect = 0.040 Identities = 25/96 (26%), Positives = 46/96 (47%), Gaps = 4/96 (4%) Query: 23 EEEKDPDAQKKEEERQEALRQQEEERKAKHARMEAEREKVRQQIRDKYGLKKKEEKEAEE 82 E+ + + Q+ ERQE +QQ+ R+ + R + E E+ QQ + +++E++E Sbjct: 276 EQLRKLERQELRRERQEEEQQQQRLRREQQLRRKQEEERREQQEERREQQERREQQEERR 335 Query: 83 KAAL----EQPCEGSLTRPKKAIPAGCGDEEEEEEE 114 + L E+ E L R ++ E+EEE Sbjct: 336 EQQLRREQEERREQQLRREQEEERREQQLRREQEEE 371 Score = 33.9 bits (76), Expect = 0.040 Identities = 24/92 (26%), Positives = 47/92 (51%), Gaps = 9/92 (9%) Query: 29 DAQKKEEERQEALRQQEEERKAKHARMEAEREKVRQQIRDKYGLKKKEEKEAEEKAALEQ 88 + Q + E ++ LR+QE +RK + E E++RQ+ ++ ++ +++ E+ L Q Sbjct: 1752 EEQLRPEREEQQLRRQERDRKFR------EEEQLRQEREEQQLRSQESDRKFREEEQLRQ 1805 Query: 89 PCEGSLTRPKKAIPAGCGDEEE---EEEESIL 117 E RP++ +EE+ EE+E L Sbjct: 1806 EREEQQLRPQQRDGKYRWEEEQLQLEEQEQRL 1837 Score = 33.5 bits (75), Expect = 0.052 Identities = 19/92 (20%), Positives = 49/92 (53%), Gaps = 4/92 (4%) Query: 23 EEEKDPDAQKKEEERQEALRQQEEERKAKHARMEAEREKVRQQIRDKYGLKKKEEKEAEE 82 +EE++ + +K+E ++ + +EE + ++ E E++R+ R + +++EE++ ++ Sbjct: 239 QEEEEKEWRKRETVLRKEEEKLQEEEPQRQRELQEEEEQLRKLERQELRRERQEEEQQQQ 298 Query: 83 KAALEQPCEGSLTRPKKAIPAGCGDEEEEEEE 114 + EQ L R ++ +E E++E Sbjct: 299 RLRREQ----QLRRKQEEERREQQEERREQQE 326 Score = 33.5 bits (75), Expect = 0.052 Identities = 17/66 (25%), Positives = 40/66 (60%), Gaps = 1/66 (1%) Query: 18 KMLGGEEEKDPDAQKKEEERQEALRQQEEERKAKHARMEAEREKVRQQIRDKYGLKKKEE 77 ++L EE+++ Q+ E+QE R+Q +R+ + R+E ++ ++ R + L ++E+ Sbjct: 632 QLLKSEEQEERRQQQLRREQQER-REQRLKREEEEERLEQRLKREHEEERREQELAEEEQ 690 Query: 78 KEAEEK 83 ++A E+ Sbjct: 691 EQARER 696 Score = 33.5 bits (75), Expect = 0.052 Identities = 21/67 (31%), Positives = 41/67 (61%), Gaps = 4/67 (5%) Query: 26 KDPDAQKKEEERQEALRQQEEERKAKHARMEAER--EKVRQQIRDKYGLKKKEEKE--AE 81 ++ + Q +EEER +Q+EE+R+ + +AE E+ RQ++ + L+++ E++ AE Sbjct: 742 RESELQWQEEERAHRQQQEEEQRRDFTWQWQAEEKSERGRQRLSARPPLREQRERQLRAE 801 Query: 82 EKAALEQ 88 E+ EQ Sbjct: 802 ERQQREQ 808 Score = 33.5 bits (75), Expect = 0.052 Identities = 19/70 (27%), Positives = 38/70 (54%), Gaps = 2/70 (2%) Query: 24 EEKDPDAQKKEEERQEALRQQEEERKAKHARMEAEREKVRQQIRDKYGLKKKEEKE--AE 81 E+++ + +E +++E EEE K + R EREK Q + ++ L+++E + E Sbjct: 792 EQRERQLRAEERQQREQRFLPEEEEKEQRRRQRREREKELQFLEEEEQLQRRERAQQLQE 851 Query: 82 EKAALEQPCE 91 E+ L++ E Sbjct: 852 EEDGLQEDQE 861 Score = 33.5 bits (75), Expect = 0.052 Identities = 19/99 (19%), Positives = 50/99 (50%), Gaps = 6/99 (6%) Query: 24 EEKDPDAQKKEEERQEALRQQEEERKAKHARMEAEREKVRQQIRDKYGLKKKEEKEAEEK 83 E + + ++ ++E ++ LR+++E+R+ + R E E++++Q R K+ ++ +++ Sbjct: 1167 ERQYREEEELQQEEEQLLREEQEKRRQERERQYREEEELQRQKR------KQRYRDEDQR 1220 Query: 84 AALEQPCEGSLTRPKKAIPAGCGDEEEEEEESILDTVLK 122 + L+ E + C E E+ + D+ L+ Sbjct: 1221 SDLKWQWEPEKENAVRDNKVYCKGRENEQFRQLEDSQLR 1259 Score = 33.5 bits (75), Expect = 0.052 Identities = 22/72 (30%), Positives = 42/72 (58%), Gaps = 6/72 (8%) Query: 23 EEEKDPDAQKKEE---ERQEALRQQEEERKAKHA---RMEAEREKVRQQIRDKYGLKKKE 76 EEE+ Q++E + ++ LR+QE ERK + R E E+E++R+Q R + L++++ Sbjct: 1695 EEEQQLRRQERERKFLQEEQQLRRQELERKFREEEQLRQETEQEQLRRQERYRKILEEEQ 1754 Query: 77 EKEAEEKAALEQ 88 + E+ L + Sbjct: 1755 LRPEREEQQLRR 1766 Score = 33.1 bits (74), Expect = 0.069 Identities = 16/71 (22%), Positives = 40/71 (56%), Gaps = 5/71 (7%) Query: 23 EEEKDPDAQKKEEER-----QEALRQQEEERKAKHARMEAEREKVRQQIRDKYGLKKKEE 77 +E ++ ++E +R ++ +R+QE+ERK + R++ +QQ+R + K +E+ Sbjct: 1565 QEREEQQLSRQERDRKFRLEEQKVRRQEQERKFMEDEQQLRRQEGQQQLRQERDRKFRED 1624 Query: 78 KEAEEKAALEQ 88 ++ ++ +Q Sbjct: 1625 EQLLQEREEQQ 1635 Score = 32.7 bits (73), Expect = 0.089 Identities = 25/95 (26%), Positives = 43/95 (45%), Gaps = 9/95 (9%) Query: 23 EEEKDPDAQKKEEERQEALRQQEEERKAKHARMEAEREKVRQQIRDKYGLKKKEEKEAEE 82 + + D Q E+QE R+QE R + R E E++ ++ ++ K+++ K EE Sbjct: 1260 DRQSQQDLQHLLGEQQERDREQERRRWQQRDRHFPEEEQLERE--EQKEAKRRDRKSQEE 1317 Query: 83 KAALEQPCEGSLTRPKKAIPAGCGDEEEEEEESIL 117 K L + E R + D + EEE +L Sbjct: 1318 KQLLREEREEKRRRQET-------DRKFREEEQLL 1345 Score = 32.7 bits (73), Expect = 0.089 Identities = 26/101 (25%), Positives = 53/101 (52%), Gaps = 11/101 (10%) Query: 27 DPDAQKKEEER------QEALRQQEEERKAKHARMEAER-EKVRQQIRDKYGLKKKE-EK 78 D D + +EEE+ ++ LR+QE +RK + + R E+ R+ ++++ L+++E E+ Sbjct: 1664 DRDRKFREEEQLLQEGEEQQLRRQERDRKFREEEQQLRRQERERKFLQEEQQLRRQELER 1723 Query: 79 EAEEKAALEQPCEGSLTRPKKAIPAGCGDEE---EEEEESI 116 + E+ L Q E R ++ +E+ E EE+ + Sbjct: 1724 KFREEEQLRQETEQEQLRRQERYRKILEEEQLRPEREEQQL 1764 Score = 32.3 bits (72), Expect = 0.12 Identities = 24/89 (26%), Positives = 41/89 (46%), Gaps = 12/89 (13%) Query: 29 DAQKKEEERQEALRQQEEERKAKHARMEAEREKVRQQIRDKYGLKKKEEKEAEEKAALEQ 88 D Q +E ++ L +QE +RK + R++ QQ+R ++ K EE+ L++ Sbjct: 1624 DEQLLQEREEQQLHRQERDRKFLEEEPQLRRQEREQQLR-----HDRDRKFREEEQLLQE 1678 Query: 89 PCEGSLTRPKKAIPAGCGDEEEEEEESIL 117 E L R ++ D + EEE L Sbjct: 1679 GEEQQLRRQER-------DRKFREEEQQL 1700 Score = 32.0 bits (71), Expect = 0.15 Identities = 19/68 (27%), Positives = 42/68 (61%), Gaps = 3/68 (4%) Query: 23 EEEKDPDAQKK-EEERQE-ALRQQEEERKAKHARMEAEREKVRQQIRDKYGLKKKEEKEA 80 EE ++ +++ EEER+E LR++++ R+ + R E + + QQ+R + L+++++ Sbjct: 357 EERREQQLRREQEEERREQQLRREQQLRREQQLRREQQLRR-EQQLRREQQLRREQQLRR 415 Query: 81 EEKAALEQ 88 E++ EQ Sbjct: 416 EQQLRREQ 423 Score = 31.6 bits (70), Expect = 0.20 Identities = 22/76 (28%), Positives = 39/76 (51%), Gaps = 2/76 (2%) Query: 16 MGKMLGGEEEKDPDAQKKEEERQEALRQQEEERKAKHARMEAEREKVRQQIRDKYGLKKK 75 +G+ G +EEK KE Q+ R+QEE+++ R E+ Q+ R K +++ Sbjct: 89 LGQATGLDEEKRARCDGKESLLQD--RRQEEDQRRFEPRDRQLEEEPGQRRRQKRQEQER 146 Query: 76 EEKEAEEKAALEQPCE 91 E E EE++ ++ E Sbjct: 147 ELAEGEEQSEKQERLE 162 Score = 31.6 bits (70), Expect = 0.20 Identities = 24/101 (23%), Positives = 51/101 (50%), Gaps = 4/101 (3%) Query: 18 KMLGGEEEKDPDAQKKEEERQEALRQQEEERKAKHARMEAEREKVRQQIRDKYGLKKKEE 77 + L E+E++ Q+ E++E R+Q+ R+ + R + R + QQ+R + L+++++ Sbjct: 349 QQLRREQEEERREQQLRREQEEERREQQLRREQQLRREQQLRRE--QQLRREQQLRREQQ 406 Query: 78 KEAEEKAALEQPC--EGSLTRPKKAIPAGCGDEEEEEEESI 116 E++ EQ E L R ++ E+E E+ + Sbjct: 407 LRREQQLRREQQLRREQQLRREQEEERHEQKHEQERREQRL 447 Score = 31.6 bits (70), Expect = 0.20 Identities = 18/77 (23%), Positives = 39/77 (50%), Gaps = 6/77 (7%) Query: 23 EEEKDPDAQKKEEERQEALRQQEEERKAKHARMEAEREKVRQQIRDKYGLKKKEEKEAEE 82 EEE+ +++ ER++ L+ EEE + + RE+ +Q ++ GL++ +E+ + Sbjct: 813 EEEEKEQRRRQRREREKELQFLEEEEQLQ------RRERAQQLQEEEDGLQEDQERRRSQ 866 Query: 83 KAALEQPCEGSLTRPKK 99 + +Q L +K Sbjct: 867 EQRRDQKWRWQLEEERK 883 Score = 31.6 bits (70), Expect = 0.20 Identities = 18/69 (26%), Positives = 36/69 (52%), Gaps = 3/69 (4%) Query: 23 EEEKDPDAQKKEEERQEALRQQEEERKAKHARM---EAEREKVRQQIRDKYGLKKKEEKE 79 + + + Q EER+E R+QE +RK + E E + +R+Q RD+ +++ + Sbjct: 1311 DRKSQEEKQLLREEREEKRRRQETDRKFREEEQLLQEREEQPLRRQERDRKFREEELRHQ 1370 Query: 80 AEEKAALEQ 88 + + LE+ Sbjct: 1371 EQGRKFLEE 1379 Score = 31.6 bits (70), Expect = 0.20 Identities = 17/57 (29%), Positives = 30/57 (52%) Query: 23 EEEKDPDAQKKEEERQEALRQQEEERKAKHARMEAEREKVRQQIRDKYGLKKKEEKE 79 EE + + +K E ++ LR+QE ERK + ++ QQ+R K +EE++ Sbjct: 1365 EELRHQEQGRKFLEEEQRLRRQERERKFLKEEQQLRCQEREQQLRQDRDRKFREEEQ 1421 Score = 31.6 bits (70), Expect = 0.20 Identities = 18/66 (27%), Positives = 38/66 (57%), Gaps = 7/66 (10%) Query: 21 GGEEEKDPDAQKKEEERQEALRQQEEE----RKAKHARMEAEREKVRQQIRDKYGLKKKE 76 G + +D D + +EEE+ LRQ+ EE R+ + + E +KVR+Q +++ ++ ++ Sbjct: 1546 GQQRRQDRDRKFREEEQ---LRQEREEQQLSRQERDRKFRLEEQKVRRQEQERKFMEDEQ 1602 Query: 77 EKEAEE 82 + +E Sbjct: 1603 QLRRQE 1608 Score = 31.2 bits (69), Expect = 0.26 Identities = 25/104 (24%), Positives = 50/104 (48%), Gaps = 12/104 (11%) Query: 23 EEEKDPDAQKKEEERQEALRQQEEERKAKHAR--------MEAEREKV----RQQIRDKY 70 EEE+ Q++EE+R++ Q + E K++ R + +RE+ +Q R++ Sbjct: 750 EEERAHRQQQEEEQRRDFTWQWQAEEKSERGRQRLSARPPLREQRERQLRAEERQQREQR 809 Query: 71 GLKKKEEKEAEEKAALEQPCEGSLTRPKKAIPAGCGDEEEEEEE 114 L ++EEKE + E+ E ++ + ++ +EEE Sbjct: 810 FLPEEEEKEQRRRQRREREKELQFLEEEEQLQRRERAQQLQEEE 853 Score = 31.2 bits (69), Expect = 0.26 Identities = 23/92 (25%), Positives = 45/92 (48%), Gaps = 6/92 (6%) Query: 23 EEEKDPDAQKKEEERQEALRQQEEERKAKHARMEAEREKVRQQIRD-KYGLKKKEEKEAE 81 E EK+ ++EE+ Q R Q+ + + + + ER + ++Q RD K+ + +EE++ Sbjct: 826 EREKELQFLEEEEQLQRRERAQQLQEEEDGLQEDQERRRSQEQRRDQKWRWQLEEERKRR 885 Query: 82 EKAALEQPCEGSLTRPKKAIPAGCGDEEEEEE 113 +P R ++ + +EEEEE Sbjct: 886 RHTLYAKPALQEQLRKEQQLL-----QEEEEE 912 Score = 31.2 bits (69), Expect = 0.26 Identities = 21/73 (28%), Positives = 39/73 (53%), Gaps = 6/73 (8%) Query: 23 EEEKDPDAQKKEEERQEALRQQEEERKAKHARMEAEREKV----RQQIRDKYGLKKKEEK 78 EEE+ ++++ RQE RQ EE + + + RE+ RQ++ +Y +++EE Sbjct: 1119 EEEQLLREEREKRRRQELERQYREEEEVQQEEEQLLREEPEKRRRQELERQY--REEEEL 1176 Query: 79 EAEEKAALEQPCE 91 + EE+ L + E Sbjct: 1177 QQEEEQLLREEQE 1189 Score = 31.2 bits (69), Expect = 0.26 Identities = 22/76 (28%), Positives = 43/76 (56%), Gaps = 4/76 (5%) Query: 26 KDPDAQKKEEERQEALRQQEEERKAKHARMEAER-EKVRQQIRDKYGLK-KKEEKEAEEK 83 +D D + +EEE+Q L +QE +RK + + R E+ R+ + ++ L+ ++ K EE+ Sbjct: 1410 QDRDRKFREEEQQ--LSRQERDRKFREEEQQVRRQERERKFLEEEQQLRQERHRKFREEE 1467 Query: 84 AALEQPCEGSLTRPKK 99 L++ E L R ++ Sbjct: 1468 QLLQEREEQQLHRQER 1483 Score = 31.2 bits (69), Expect = 0.26 Identities = 17/74 (22%), Positives = 41/74 (55%), Gaps = 3/74 (4%) Query: 18 KMLGGEEEKDPDAQKKEEERQEALRQQEEE---RKAKHARMEAEREKVRQQIRDKYGLKK 74 K L E++ + +K E ++ L+++EE+ R+ + + E +++R+Q RD+ ++ Sbjct: 1447 KFLEEEQQLRQERHRKFREEEQLLQEREEQQLHRQERDRKFLEEEQQLRRQERDRKFREQ 1506 Query: 75 KEEKEAEEKAALEQ 88 + + E+ LE+ Sbjct: 1507 ELRSQEPERKFLEE 1520 Score = 31.2 bits (69), Expect = 0.26 Identities = 21/71 (29%), Positives = 39/71 (54%), Gaps = 4/71 (5%) Query: 23 EEEKDPDAQKKEEERQEALRQQEEERKAKHARMEAEREKVRQQIRD-KYGLKKKEEKEAE 81 EE+ P+ ++++ RQE R+ EE + R E E +++R Q D K+ +++ +E E Sbjct: 1752 EEQLRPEREEQQLRRQERDRKFREE---EQLRQEREEQQLRSQESDRKFREEEQLRQERE 1808 Query: 82 EKAALEQPCEG 92 E+ Q +G Sbjct: 1809 EQQLRPQQRDG 1819 Score = 30.8 bits (68), Expect = 0.34 Identities = 18/71 (25%), Positives = 38/71 (53%), Gaps = 4/71 (5%) Query: 18 KMLGGEEEKDPDAQKKEEERQEALRQQEEERKAKHARMEAEREKVRQQIRDKYGLKKKEE 77 + L E+E+ + + K +E +E L+Q R ++ E+E+ R+Q+ + K+ E+ Sbjct: 505 QQLRREQEERREQRLKRQEEEERLQQ----RLRSEQQLRREQEERREQLLKREEEKRLEQ 560 Query: 78 KEAEEKAALEQ 88 + E++ EQ Sbjct: 561 ERREQRLKREQ 571 Score = 30.8 bits (68), Expect = 0.34 Identities = 16/60 (26%), Positives = 35/60 (58%), Gaps = 3/60 (5%) Query: 23 EEEKDPDAQKKEE---ERQEALRQQEEERKAKHARMEAEREKVRQQIRDKYGLKKKEEKE 79 EEE+ Q+++ E ++ +R+QE ERK + +E+ R+ ++ L+++EE++ Sbjct: 1418 EEEQQLSRQERDRKFREEEQQVRRQERERKFLEEEQQLRQERHRKFREEEQLLQEREEQQ 1477 Score = 30.8 bits (68), Expect = 0.34 Identities = 22/89 (24%), Positives = 45/89 (50%), Gaps = 12/89 (13%) Query: 23 EEEKDPDAQKKEEE-RQEALRQQEEERK-----------AKHARMEAEREKVRQQIRDKY 70 EEE+ Q+++ + R++ LR QE ERK + + E +++R+Q R + Sbjct: 1489 EEEQQLRRQERDRKFREQELRSQEPERKFLEEEQQLHRQQRQRKFLQEEQQLRRQERGQQ 1548 Query: 71 GLKKKEEKEAEEKAALEQPCEGSLTRPKK 99 + ++ K EE+ ++ E L+R ++ Sbjct: 1549 RRQDRDRKFREEEQLRQEREEQQLSRQER 1577 Score = 30.8 bits (68), Expect = 0.34 Identities = 13/59 (22%), Positives = 35/59 (59%) Query: 25 EKDPDAQKKEEERQEALRQQEEERKAKHARMEAEREKVRQQIRDKYGLKKKEEKEAEEK 83 E++P +++E E+Q + + R+ + E E +++R+Q RD+ +++++ +E+ Sbjct: 1647 EEEPQLRRQEREQQLRHDRDRKFREEEQLLQEGEEQQLRRQERDRKFREEEQQLRRQER 1705 Score = 30.4 bits (67), Expect = 0.44 Identities = 20/93 (21%), Positives = 45/93 (48%), Gaps = 4/93 (4%) Query: 23 EEEKDPDAQKKEEERQEALRQQEEERKAKHARMEAEREKVRQQIRDKYGLKKKEEKEAEE 82 E E+ P + +ER R++E + + + E +++R+Q R++ LK++++ +E Sbjct: 1347 EREEQP---LRRQERDRKFREEELRHQEQGRKFLEEEQRLRRQERERKFLKEEQQLRCQE 1403 Query: 83 K-AALEQPCEGSLTRPKKAIPAGCGDEEEEEEE 114 + L Q + ++ + D + EEE Sbjct: 1404 REQQLRQDRDRKFREEEQQLSRQERDRKFREEE 1436 Score = 30.0 bits (66), Expect = 0.58 Identities = 18/66 (27%), Positives = 39/66 (59%), Gaps = 7/66 (10%) Query: 23 EEEKDPDAQKKEEERQEALRQQEEERKAKHARMEAEREKVRQQIRDKYGLKKKEEKEAEE 82 +EE+ K+EEE++ E+ER+ + R++ E+E+ R Q+ + ++++ + E+ Sbjct: 542 QEERREQLLKREEEKR-----LEQERREQ--RLKREQEERRDQLLKREEERRQQRLKREQ 594 Query: 83 KAALEQ 88 + LEQ Sbjct: 595 EERLEQ 600 Score = 29.6 bits (65), Expect = 0.76 Identities = 14/63 (22%), Positives = 37/63 (58%), Gaps = 3/63 (4%) Query: 23 EEEKDPDAQKKEEERQEALRQQEEE---RKAKHARMEAEREKVRQQIRDKYGLKKKEEKE 79 E++ D +K E ++ L++ EE+ R+ + + E +++R+Q R++ L+++++ Sbjct: 1658 EQQLRHDRDRKFREEEQLLQEGEEQQLRRQERDRKFREEEQQLRRQERERKFLQEEQQLR 1717 Query: 80 AEE 82 +E Sbjct: 1718 RQE 1720 Score = 29.6 bits (65), Expect = 0.76 Identities = 19/84 (22%), Positives = 42/84 (50%), Gaps = 6/84 (7%) Query: 33 KEEERQEALRQQEEERKAKHARMEAEREKVRQQIRDKYGLKKKEEKEAEEKAALEQPCEG 92 +EEE+ +QE+ R+ + R E E++R + ++ +++ +++ E+ L Q E Sbjct: 1726 REEEQLRQETEQEQLRRQERYRKILEEEQLRPEREEQQLRRQERDRKFREEEQLRQEREE 1785 Query: 93 SLTRPKKAIPAGCGDEEEEEEESI 116 R +++ D + EEE + Sbjct: 1786 QQLRSQES------DRKFREEEQL 1803 Score = 29.3 bits (64), Expect = 0.99 Identities = 17/61 (27%), Positives = 38/61 (62%), Gaps = 3/61 (4%) Query: 25 EKDPDAQKKEEER--QEALRQQEEERKAKHARMEAEREKVRQQIRDKYGLKKKEEKEAEE 82 ++D + ++ +E+R Q+ Q EEERK + + A + +++Q+R + L ++EE+E + Sbjct: 857 QEDQERRRSQEQRRDQKWRWQLEEERKRRRHTLYA-KPALQEQLRKEQQLLQEEEEELQR 915 Query: 83 K 83 + Sbjct: 916 E 916 Score = 28.9 bits (63), Expect = 1.3 Identities = 14/59 (23%), Positives = 34/59 (57%), Gaps = 2/59 (3%) Query: 27 DPDAQKKEEERQEALRQQEEE--RKAKHARMEAEREKVRQQIRDKYGLKKKEEKEAEEK 83 + + Q + +E Q+ LRQ+ + R+ + E E +++ +Q RD+ L+++ + +E+ Sbjct: 1599 EDEQQLRRQEGQQQLRQERDRKFREDEQLLQEREEQQLHRQERDRKFLEEEPQLRRQER 1657 Score = 28.5 bits (62), Expect = 1.7 Identities = 18/77 (23%), Positives = 38/77 (49%), Gaps = 2/77 (2%) Query: 18 KMLGGEEEKDPDAQ--KKEEERQEALRQQEEERKAKHARMEAEREKVRQQIRDKYGLKKK 75 + L EE+K+ + K +EE+Q ++EE+R+ + + E+ Q R++ L+++ Sbjct: 1297 EQLEREEQKEAKRRDRKSQEEKQLLREEREEKRRRQETDRKFREEEQLLQEREEQPLRRQ 1356 Query: 76 EEKEAEEKAALEQPCEG 92 E + L +G Sbjct: 1357 ERDRKFREEELRHQEQG 1373 Score = 28.5 bits (62), Expect = 1.7 Identities = 17/60 (28%), Positives = 29/60 (48%) Query: 24 EEKDPDAQKKEEERQEALRQQEEERKAKHARMEAEREKVRQQIRDKYGLKKKEEKEAEEK 83 EE+ +K E QE +++E++R+ + R E RQQ ++ + E K E K Sbjct: 1848 EEQFATQEKSRREEQELWQEEEQKRRQERERKLREEHIRRQQKEEQRHRQVGEIKSQEGK 1907 Score = 28.1 bits (61), Expect = 2.2 Identities = 19/69 (27%), Positives = 36/69 (52%), Gaps = 3/69 (4%) Query: 23 EEEKDPDAQKKEEE---RQEALRQQEEERKAKHARMEAEREKVRQQIRDKYGLKKKEEKE 79 EEE+ Q++E + ++ LR QE E++ + R RE+ +Q R + K +EE++ Sbjct: 1378 EEEQRLRRQERERKFLKEEQQLRCQEREQQLRQDRDRKFREEEQQLSRQERDRKFREEEQ 1437 Query: 80 AEEKAALEQ 88 + E+ Sbjct: 1438 QVRRQERER 1446 Score = 27.7 bits (60), Expect = 2.9 Identities = 22/112 (19%), Positives = 53/112 (47%), Gaps = 3/112 (2%) Query: 23 EEEKDPDAQKKEEERQEALRQQEEERKAKHARMEAEREKVRQQIRDKYGLKKKEEKEAEE 82 EE + + Q EE ++ RQ+ E + + ++ E E++ ++ ++K +++ E++ E Sbjct: 1144 EEVQQEEEQLLREEPEKRRRQELERQYREEEELQQEEEQLLREEQEK--RRQERERQYRE 1201 Query: 83 KAALEQPCEGSLTRPKKAIPAGCGDEEEEEEESILDTVLKYLPGPLQDMFKK 134 + L++ R + E E+E ++ D + Y G + F++ Sbjct: 1202 EEELQRQKRKQRYRDEDQRSDLKWQWEPEKENAVRDNKV-YCKGRENEQFRQ 1252 Score = 27.3 bits (59), Expect = 3.8 Identities = 17/59 (28%), Positives = 32/59 (54%), Gaps = 3/59 (5%) Query: 23 EEEKDPDAQKKEEERQEALRQQEEERKAKHARMEAEREKVRQQIRDKYGLKKKEEKEAE 81 EEE + ++ E E R+QE ER+ R E E ++ +Q+ + K+++E+E + Sbjct: 1143 EEEVQQEEEQLLREEPEKRRRQELERQ---YREEEELQQEEEQLLREEQEKRRQERERQ 1198 Score = 26.6 bits (57), Expect = 6.4 Identities = 14/60 (23%), Positives = 36/60 (60%), Gaps = 1/60 (1%) Query: 29 DAQKKEEERQEALRQQEEERKAKHARMEAEREKVRQQIRDKYGLKKKEEKEAEEKAALEQ 88 + Q + EE+++ LR QE +R+ + A +EK R++ ++ + ++++ ++ E+ E+ Sbjct: 1825 EEQLQLEEQEQRLR-QERDRQYRAEEQFATQEKSRREEQELWQEEEQKRRQERERKLREE 1883 Score = 26.2 bits (56), Expect = 8.4 Identities = 20/71 (28%), Positives = 40/71 (56%), Gaps = 9/71 (12%) Query: 23 EEEKDPDAQKKEE---ERQEALRQQE--EERKAKHARMEAEREKVRQQIRDKYGLKKKEE 77 EEE+ Q+++ + ++ LR+QE ++R+ R E E++RQ+ R++ L ++E Sbjct: 1519 EEEQQLHRQQRQRKFLQEEQQLRRQERGQQRRQDRDRKFREEEQLRQE-REEQQLSRQER 1577 Query: 78 KEAEEKAALEQ 88 + K LE+ Sbjct: 1578 ---DRKFRLEE 1585 Score = 26.2 bits (56), Expect = 8.4 Identities = 16/62 (25%), Positives = 37/62 (59%), Gaps = 4/62 (6%) Query: 23 EEEKDPDAQKKEEERQEALRQQEEERKAKHARMEAEREKVRQQIRD-KYGLKKKEEKEAE 81 EE++ ++ ++ RQ+ R+ EE + R E E +++ +Q RD K+ L++++ + E Sbjct: 1536 EEQQLRRQERGQQRRQDRDRKFREE---EQLRQEREEQQLSRQERDRKFRLEEQKVRRQE 1592 Query: 82 EK 83 ++ Sbjct: 1593 QE 1594 >gi|22758136 MAP7 domain containing 2 [Homo sapiens] Length = 732 Score = 47.4 bits (111), Expect = 4e-06 Identities = 26/80 (32%), Positives = 52/80 (65%), Gaps = 6/80 (7%) Query: 23 EEEK---DPDAQKKEEERQEALRQQEEERKAKHARMEAEREKVRQQIRDKYGLKKKEEKE 79 EEE+ + +A+K+EEER+ RQ+EE++K + E+ +++ ++ LK+K+E+E Sbjct: 441 EEERLRLEEEARKQEEERK---RQEEEKKKQEGEEKRKAGEEAKRKAEEELLLKEKQEQE 497 Query: 80 AEEKAALEQPCEGSLTRPKK 99 +EKA +E+ E + T+ ++ Sbjct: 498 KQEKAMIEKQKEAAETKARE 517 Score = 40.8 bits (94), Expect = 3e-04 Identities = 22/95 (23%), Positives = 56/95 (58%), Gaps = 3/95 (3%) Query: 24 EEKDPDAQKKEEERQEALRQQEEERKAKHARMEAEREKVRQQIRDKYGLKKKEEKEAEEK 83 +++ + ++ E+E Q+ L ++E +RKA+ R+ E E +Q+ K ++K+++E EEK Sbjct: 414 QKEQEEQERVEKEEQDRLEREELKRKAEEERLRLEEEARKQEEERKRQEEEKKKQEGEEK 473 Query: 84 AALEQPCEGSLTRPKKAIPAGCGDEEEEEEESILD 118 + E + + ++ + E+E++E+++++ Sbjct: 474 ---RKAGEEAKRKAEEELLLKEKQEQEKQEKAMIE 505 Score = 33.9 bits (76), Expect = 0.040 Identities = 30/117 (25%), Positives = 59/117 (50%), Gaps = 9/117 (7%) Query: 8 ALGGATKD---MGKMLGGEEEKDPDAQKKEEERQEAL---RQQEEERKAKHARMEAEREK 61 A GG ++ +GK G + A+ E+R++A Q+E+ER K + ERE+ Sbjct: 376 AAGGKAENSAALGKPTAGTTDAGEAAKILAEKRRQARLQKEQEEQERVEKEEQDRLEREE 435 Query: 62 VRQQIRD-KYGLKKKEEKEAEEKAALEQPCEGSLTRPKKAIPAGCGDEEEEEEESIL 117 ++++ + + L+++ K+ EE+ E+ E ++ AG + + EEE +L Sbjct: 436 LKRKAEEERLRLEEEARKQEEERKRQEE--EKKKQEGEEKRKAGEEAKRKAEEELLL 490 Score = 33.5 bits (75), Expect = 0.052 Identities = 20/83 (24%), Positives = 51/83 (61%), Gaps = 8/83 (9%) Query: 24 EEKDPDAQKKEEERQEALRQQEEE--RKAKHARMEAEREKVRQQIRDKY-GLKKKEEKEA 80 +E+ A+++ EER++ L +E++ K K AR++ E+ Q+ +++ L+++ ++E Sbjct: 52 DERQRLAKERREEREKCLAAREQQILEKQKRARLQYEK-----QMEERWRKLEEQRQRED 106 Query: 81 EEKAALEQPCEGSLTRPKKAIPA 103 +++AA+E+ + L ++ + A Sbjct: 107 QKRAAVEEKRKQKLREEEERLEA 129 Score = 33.1 bits (74), Expect = 0.069 Identities = 28/100 (28%), Positives = 50/100 (50%), Gaps = 13/100 (13%) Query: 23 EEEKDPDAQKKEEERQEALRQQEEERKAKHARMEAEREKVRQQIRDKYGLKKKEEKEAEE 82 EE+K + ++K + +EA R+ EEE K EK Q+ ++K ++K +KEA E Sbjct: 463 EEKKKQEGEEKRKAGEEAKRKAEEELLLK--------EKQEQEKQEKAMIEK--QKEAAE 512 Query: 83 KAALEQPCEGSLTRPKKAIPAGCGDEEEEEEESILDTVLK 122 A E + L R + + ++E E + +D ++K Sbjct: 513 TKAREVAEQMRLEREQIMLQI---EQERLERKKRIDEIMK 549 Score = 27.3 bits (59), Expect = 3.8 Identities = 17/52 (32%), Positives = 32/52 (61%), Gaps = 7/52 (13%) Query: 23 EEEKDPDAQKK---EEERQEALRQQEEERKAKHARMEAEREKVRQ-QIRDKY 70 EE++ + QK+ EE+R++ LR++EE + A M E+ +Q +++ KY Sbjct: 99 EEQRQREDQKRAAVEEKRKQKLREEEERLE---AMMRRSLERTQQLELKKKY 147 >gi|31795561 complexin 4 [Homo sapiens] Length = 160 Score = 47.0 bits (110), Expect = 5e-06 Identities = 40/132 (30%), Positives = 66/132 (50%), Gaps = 17/132 (12%) Query: 1 MDFVMKQALGGATKDMGKMLGGEEEK------DPDA-----QKKEEERQEALRQQEEERK 49 M F+MK + K++G G EE K DP A +++ EE Q+ + +++ ER Sbjct: 1 MAFLMKSMISNQVKNLGFGGGSEENKEEGGASDPAAAQGMTREEYEEYQKQMIEEKMERD 60 Query: 50 AKHARMEAEREKVRQQIRDKYGLKKKEEKEAEEKAALEQPCEGSLTRPKKAIPAGCGDEE 109 A + +AER +R +R+KY L K E E + + A + + P+ D+E Sbjct: 61 AAFTQKKAERACLRVHLREKYRLPKSEMDENQIQMAGD-----DVDLPEDLRKMVDEDQE 115 Query: 110 EEEE-ESILDTV 120 EEE+ +SIL + Sbjct: 116 EEEDKDSILGQI 127 >gi|55741709 RNA binding motif protein 25 [Homo sapiens] Length = 843 Score = 45.1 bits (105), Expect = 2e-05 Identities = 24/76 (31%), Positives = 45/76 (59%), Gaps = 1/76 (1%) Query: 13 TKDMGKMLGGEEEKDPDAQKKEEERQEALRQQEEERKAKHARMEAEREKVRQQIRDKYGL 72 + D K EK D +++ E +E R++E ER+ + R E ERE+ R++ +DK Sbjct: 374 SSDRNKDRSRSREKSRDRERERERERERERERERERERERER-EREREREREREKDKKRD 432 Query: 73 KKKEEKEAEEKAALEQ 88 ++++E++A E+ LE+ Sbjct: 433 REEDEEDAYERRKLER 448 Score = 42.4 bits (98), Expect = 1e-04 Identities = 29/106 (27%), Positives = 55/106 (51%), Gaps = 12/106 (11%) Query: 13 TKDMGKMLGGEEEKDPDAQKKEEERQEA---LRQQEEERKAKHARMEAEREKVRQQIRDK 69 ++++ K ++ + + KKE+ERQE R++E ER+ + R E ERE+ R++ R+K Sbjct: 278 SREISKFRDTHKKLEEEKGKKEKERQEIEKERRERERERERERERREREREREREREREK 337 Query: 70 YGLKKKEEKEAEEKAALEQPCEGSLTRPKKAIPAGCGDEEEEEEES 115 +K+ E+E E ++ E R ++ D + + E S Sbjct: 338 ---EKERERERERDRDRDRTKERDRDRDRER------DRDRDRERS 374 Score = 40.8 bits (94), Expect = 3e-04 Identities = 23/91 (25%), Positives = 46/91 (50%) Query: 23 EEEKDPDAQKKEEERQEALRQQEEERKAKHARMEAEREKVRQQIRDKYGLKKKEEKEAEE 82 E E++ + +++ E +E R++E ER+ + R + ++ + D Y +K E K E+ Sbjct: 394 EREREREREREREREREREREREREREREREREKDKKRDREEDEEDAYERRKLERKLREK 453 Query: 83 KAALEQPCEGSLTRPKKAIPAGCGDEEEEEE 113 +AA ++ + R +K + E EEE Sbjct: 454 EAAYQERLKNWEIRERKKTREYEKEAEREEE 484 Score = 40.0 bits (92), Expect = 6e-04 Identities = 29/106 (27%), Positives = 53/106 (50%), Gaps = 16/106 (15%) Query: 18 KMLGGEEEKDPDAQKKEEERQEALRQQEEERKAKHARMEAEREKVRQ-QIRDKYGLKKKE 76 +M E ++ + ++ EE RQ L + + A+ RME E E+ RQ QI+ + +++E Sbjct: 528 EMEADERDRKREKEELEEIRQRLLAEGHPDPDAELQRMEQEAERRRQPQIKQEPESEEEE 587 Query: 77 EKEAEEKAALEQPCEGSLTRPKKAIPAGCGDEEEEEEESILDTVLK 122 E++ E++ E+P E +EEE E++ L L+ Sbjct: 588 EEKQEKEEKREEPME---------------EEEEPEQKPCLKPTLR 618 Score = 37.7 bits (86), Expect = 0.003 Identities = 25/103 (24%), Positives = 52/103 (50%), Gaps = 16/103 (15%) Query: 13 TKDMGKMLGGEEEKDPDAQKKEEERQEALRQQEEERKAKHARMEAEREKVRQQIRDKYGL 72 TK+ + E ++D D ++ + ++ R +E+ R + ERE+ R++ R++ Sbjct: 354 TKERDRDRDRERDRDRDRERSSDRNKDRSRSREKSR-------DRERERERERERER--- 403 Query: 73 KKKEEKEAEEKAALEQPCEGSLTRPKKAIPAGCGDEEEEEEES 115 +++ E+E E + E+ E + KK D EE+EE++ Sbjct: 404 EREREREREREREREREREREREKDKKR------DREEDEEDA 440 Score = 37.7 bits (86), Expect = 0.003 Identities = 26/90 (28%), Positives = 46/90 (51%), Gaps = 8/90 (8%) Query: 14 KDMGKMLGGEEEKDPDAQKKEEERQEALRQQEEERKAKHARMEAEREKVRQQIRDKYGLK 73 +++ + L E DPDA+ + E QEA R+++ + K + E E EK ++ + Sbjct: 544 EEIRQRLLAEGHPDPDAELQRME-QEAERRRQPQIKQEPESEEEEEEKQEKE-------E 595 Query: 74 KKEEKEAEEKAALEQPCEGSLTRPKKAIPA 103 K+EE EE+ ++PC RP + P+ Sbjct: 596 KREEPMEEEEEPEQKPCLKPTLRPISSAPS 625 Score = 37.0 bits (84), Expect = 0.005 Identities = 23/77 (29%), Positives = 42/77 (54%), Gaps = 2/77 (2%) Query: 23 EEEKDPDAQKKEEERQEALRQQEEERKAKHARMEAEREKVRQQIRDKYGLKKKE-EKEAE 81 + E+ D K +E R +E ER+ + R E ERE+ R++ R++ +++E E+E + Sbjct: 370 DRERSSDRNKDRSRSREKSRDRERERERERER-EREREREREREREREREREREREREKD 428 Query: 82 EKAALEQPCEGSLTRPK 98 +K E+ E + R K Sbjct: 429 KKRDREEDEEDAYERRK 445 Score = 35.0 bits (79), Expect = 0.018 Identities = 19/91 (20%), Positives = 47/91 (51%), Gaps = 7/91 (7%) Query: 23 EEEKDPDAQKKEEERQEALRQQEEERKAKHARMEAEREKVRQQIRDKYGLKKKEEKEAEE 82 E E++ + +++E ER+ ++ E+ K + E +R++ R + RD+ ++ +++ + Sbjct: 313 ERERERERERREREREREREREREKEKERERERERDRDRDRTKERDR-DRDRERDRDRDR 371 Query: 83 KAALEQPCEGSLTRPKKAIPAGCGDEEEEEE 113 + + ++ + S +R K D E E E Sbjct: 372 ERSSDRNKDRSRSREKSR------DRERERE 396 Score = 33.9 bits (76), Expect = 0.040 Identities = 20/86 (23%), Positives = 42/86 (48%) Query: 14 KDMGKMLGGEEEKDPDAQKKEEERQEALRQQEEERKAKHARMEAEREKVRQQIRDKYGLK 73 +D ++ E K D KK EE + ++ +E + + E ERE+ R++ + + Sbjct: 271 EDKRDLISREISKFRDTHKKLEEEKGKKEKERQEIEKERRERERERERERERRERERERE 330 Query: 74 KKEEKEAEEKAALEQPCEGSLTRPKK 99 ++ E+E E++ E+ + R K+ Sbjct: 331 REREREKEKERERERERDRDRDRTKE 356 Score = 30.4 bits (67), Expect = 0.44 Identities = 19/92 (20%), Positives = 45/92 (48%), Gaps = 6/92 (6%) Query: 23 EEEKDPDAQKKEEERQEALRQQEEERKAKHARMEAEREKVRQQIRDKYGLKKKEEKEAEE 82 E EKD ++E+E ++A +++ ERK + + +IR+ +K+ +E E+ Sbjct: 424 EREKDKKRDREEDE-EDAYERRKLERKLREKEAAYQERLKNWEIRE-----RKKTREYEK 477 Query: 83 KAALEQPCEGSLTRPKKAIPAGCGDEEEEEEE 114 +A E+ + + K + D +++ ++ Sbjct: 478 EAEREEERRREMAKEAKRLKEFLEDYDDDRDD 509 Score = 30.0 bits (66), Expect = 0.58 Identities = 22/92 (23%), Positives = 47/92 (51%), Gaps = 2/92 (2%) Query: 23 EEEKDPDAQKKEEERQEALRQQEEERKAKHARMEAEREKVRQQIRDKYGLKKKEEKEAEE 82 ++++D + Q+ LR +E+E +A + E+E++ ++IR + + + +AE Sbjct: 504 DDDRDDPKYYRGSALQKRLRDREKEMEADERDRKREKEEL-EEIRQRLLAEGHPDPDAEL 562 Query: 83 KAALEQPCEGSLTRPKKAIPAGCGDEEEEEEE 114 + +EQ E K P +EEE++E+ Sbjct: 563 Q-RMEQEAERRRQPQIKQEPESEEEEEEKQEK 593 Score = 26.6 bits (57), Expect = 6.4 Identities = 21/91 (23%), Positives = 45/91 (49%), Gaps = 12/91 (13%) Query: 25 EKDPDAQKKEEERQEALRQQEEERKAKHARMEAEREKVRQQIRDKYGLKKKEEKEAE-EK 83 ++D +A + EE++++ + ++ + + H ++E E+ G K+KE +E E E+ Sbjct: 261 KEDINAIEMEEDKRDLISREISKFRDTHKKLEEEK-----------GKKEKERQEIEKER 309 Query: 84 AALEQPCEGSLTRPKKAIPAGCGDEEEEEEE 114 E+ E R ++ E E+E+E Sbjct: 310 RERERERERERERREREREREREREREKEKE 340 >gi|239745079 PREDICTED: Putative golgin subfamily A member 6-like protein 6 [Homo sapiens] Length = 724 Score = 44.7 bits (104), Expect = 2e-05 Identities = 23/79 (29%), Positives = 52/79 (65%), Gaps = 6/79 (7%) Query: 13 TKDMGKMLGGEEEKDPDAQKKEEERQEALRQQEEERKAKHARMEAEREKVRQQIRDKYGL 72 T++ + +G +EEK + ++K +E++E +R+QEE+ + + ++ + EK+R+Q + + Sbjct: 608 TQEQEEKMGEQEEKMCEQEEKMQEQEEKMRRQEEKIREQEKKIREQEEKIREQ---EEMM 664 Query: 73 KKKEEKEAEEKAALEQPCE 91 +++EEK E++ E+ CE Sbjct: 665 QEQEEKMWEQE---EKMCE 680 Score = 42.0 bits (97), Expect = 1e-04 Identities = 23/92 (25%), Positives = 53/92 (57%), Gaps = 7/92 (7%) Query: 23 EEEKDPDAQKKEEERQEALRQQEEERKAKHARMEAEREKVRQQIRDKYGLKKKEEKEAEE 82 +EE + ++K E++E + +QEE+ + + +M + EK+R+Q + ++++EEK E+ Sbjct: 604 QEEMTQEQEEKMGEQEEKMCEQEEKMQEQEEKMRRQEEKIREQEKK---IREQEEKIREQ 660 Query: 83 KAALEQPCEGSLTRPKKAIPAGCGDEEEEEEE 114 + +++ E + +K C EE+ +E+ Sbjct: 661 EEMMQEQEEKMWEQEEKM----CEQEEKMQEQ 688 Score = 38.9 bits (89), Expect = 0.001 Identities = 27/101 (26%), Positives = 57/101 (56%), Gaps = 12/101 (11%) Query: 23 EEEKDPDAQKKEEERQEALRQQEEERKAKHARMEAEREKVRQQ----IRDKYGLKKKEEK 78 E+E+ ++K E++E +R+QEE+ + +M + EK+R+Q R + ++++EEK Sbjct: 534 EQEEIWRQKEKIHEQEEKIRKQEEKMWRQEEKMHDQEEKIREQEEKVWRQEEKIREQEEK 593 Query: 79 EAEEKAALEQPCEGSLTRPKKAIPAGCGDEEE---EEEESI 116 E++ + + E + + +K G++EE E+EE + Sbjct: 594 IREQEEKIREQEEMTQEQEEK-----MGEQEEKMCEQEEKM 629 Score = 38.1 bits (87), Expect = 0.002 Identities = 22/74 (29%), Positives = 45/74 (60%), Gaps = 8/74 (10%) Query: 23 EEEKDPDAQKKEEE------RQEALRQQEEERKAKHARMEAEREKVRQQ--IRDKYGLKK 74 EEEK + +K++E+ ++E +R+QEE+ + + +M + EK+ +Q IR++ ++ Sbjct: 462 EEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEEKMWRQEEKIHEQEKIREEEKRQE 521 Query: 75 KEEKEAEEKAALEQ 88 +EE +E+ EQ Sbjct: 522 QEEMWRQEEKIREQ 535 Score = 38.1 bits (87), Expect = 0.002 Identities = 21/70 (30%), Positives = 41/70 (58%), Gaps = 4/70 (5%) Query: 23 EEEKDPDAQKKEEERQEALRQQEEERKAKHARMEAEREKVRQQ----IRDKYGLKKKEEK 78 +EEK + +KK E++E +R+QEE + + +M + EK+ +Q + ++++EEK Sbjct: 639 QEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEK 698 Query: 79 EAEEKAALEQ 88 E++ L Q Sbjct: 699 MWEQEVRLRQ 708 Score = 38.1 bits (87), Expect = 0.002 Identities = 21/78 (26%), Positives = 45/78 (57%), Gaps = 4/78 (5%) Query: 14 KDMGKMLGGEEEKDPDAQKKEEERQEALRQQEEERKAKHARMEAEREKVRQQ----IRDK 69 ++ K + +EEK + ++ +E++E + +QEE+ + +M+ + EK+R+Q + Sbjct: 644 REQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQE 703 Query: 70 YGLKKKEEKEAEEKAALE 87 L+++EEK E + LE Sbjct: 704 VRLRQQEEKMQEHQEHLE 721 Score = 37.7 bits (86), Expect = 0.003 Identities = 26/96 (27%), Positives = 51/96 (53%), Gaps = 6/96 (6%) Query: 24 EEKDPDAQKKEEERQEALRQQEEERKAKHARMEAEREKVRQQ---IRDKYGLKKKEEKEA 80 EEK + ++K E++E +R+QEE+ + + M + EK+R+Q + +K +++E+ Sbjct: 374 EEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMM 433 Query: 81 EEKAALEQPCEGSLTRPKKAIPAGCGDEEEEEEESI 116 EK + E + +K +E+ +EEE I Sbjct: 434 WEKEEKIRELEEKMHEQEKIREQ---EEKRQEEEKI 466 Score = 37.4 bits (85), Expect = 0.004 Identities = 28/95 (29%), Positives = 52/95 (54%), Gaps = 7/95 (7%) Query: 25 EKDPDAQKKEE---ERQEALRQQEEERKAKHARMEAEREKVRQQ--IRDKYGLKKKEEKE 79 EK+ +++EE E++E +R+QEE K ++ EK+ +Q IR++ +++EEK Sbjct: 407 EKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKI 466 Query: 80 AEEKAALEQPCEGSLTRPKKAIPAGCGDEEEEEEE 114 E++ EQ E + R ++ I E+EE+ Sbjct: 467 REQEKRQEQ--EAKMWRQEEKIREQEEKIREQEEK 499 Score = 34.7 bits (78), Expect = 0.024 Identities = 24/70 (34%), Positives = 43/70 (61%), Gaps = 5/70 (7%) Query: 18 KMLGGEEEKDPDAQKKEEERQEALRQQEEERKAKHARMEAER--EKVRQQIRDKYGLKKK 75 +M+ +EEK + ++K E QE +R+QEE+R+ + E E+ E+ + R + ++++ Sbjct: 431 EMMWEKEEKIRELEEKMHE-QEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQ 489 Query: 76 EEK--EAEEK 83 EEK E EEK Sbjct: 490 EEKIREQEEK 499 Score = 34.3 bits (77), Expect = 0.031 Identities = 18/61 (29%), Positives = 39/61 (63%), Gaps = 1/61 (1%) Query: 23 EEEKDPDAQKKEEERQEALRQQEEERKAKHARMEAEREKVRQQIRDKYGLKKKEEKEAEE 82 +EEK ++K E+++ +R+QEE+ + + M+ + EK+ +Q +K ++++ +E EE Sbjct: 632 QEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQ-EEKMCEQEEKMQEQEE 690 Query: 83 K 83 K Sbjct: 691 K 691 Score = 33.9 bits (76), Expect = 0.040 Identities = 17/69 (24%), Positives = 41/69 (59%), Gaps = 3/69 (4%) Query: 23 EEEKDPDAQKKEEERQEALRQQEEERKAKHARMEAEREKVR---QQIRDKYGLKKKEEKE 79 +EE + ++K ++E + ++EE+ + + M + EK+R +++ ++ ++++EEK Sbjct: 401 QEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKR 460 Query: 80 AEEKAALEQ 88 EE+ EQ Sbjct: 461 QEEEKIREQ 469 Score = 33.9 bits (76), Expect = 0.040 Identities = 19/69 (27%), Positives = 41/69 (59%), Gaps = 1/69 (1%) Query: 15 DMGKMLGGEEEKDPDAQKKEEERQEALRQQEEERKAKHARMEAEREKVRQQIRDKYGLKK 74 D + + +EEK ++K E++E +R+QEE+ + + + + EK+ +Q +K ++ Sbjct: 568 DQEEKIREQEEKVWRQEEKIREQEEKIREQEEKIREQEEMTQEQEEKMGEQ-EEKMCEQE 626 Query: 75 KEEKEAEEK 83 ++ +E EEK Sbjct: 627 EKMQEQEEK 635 Score = 32.7 bits (73), Expect = 0.089 Identities = 25/75 (33%), Positives = 44/75 (58%), Gaps = 10/75 (13%) Query: 23 EEEKDPDAQKKEEERQEALRQQE--EERKAKHARME----AEREKVRQQIRDKYGLKKK- 75 E+EK + ++K +E +E +R+QE +E++AK R E + EK+R+Q + ++K Sbjct: 449 EQEKIREQEEKRQE-EEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEEKMWRQEEKI 507 Query: 76 --EEKEAEEKAALEQ 88 +EK EE+ EQ Sbjct: 508 HEQEKIREEEKRQEQ 522 Score = 32.7 bits (73), Expect = 0.089 Identities = 22/97 (22%), Positives = 53/97 (54%), Gaps = 8/97 (8%) Query: 23 EEEKDPDAQKKEEERQEALRQQEEERKAKHARMEAEREKVRQQIRDKYGLKKKEEKEAEE 82 +EEK + ++K ++E + +QE+ R+ + + + E + ++IR++ + +++EK E+ Sbjct: 489 QEEKIREQEEKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKIHEQ 548 Query: 83 KAALEQPCEGSLTRPKKAIPAGCGDEEE---EEEESI 116 + + + E + +K D+EE E+EE + Sbjct: 549 EEKIRKQEEKMWRQEEK-----MHDQEEKIREQEEKV 580 Score = 32.7 bits (73), Expect = 0.089 Identities = 28/106 (26%), Positives = 50/106 (47%), Gaps = 8/106 (7%) Query: 14 KDMGKMLGGEEEKDPDAQKKEEERQEALRQQE-----EERKAKHARMEAEREKVRQQIRD 68 K KM EE+ +K E+ ++ RQ+E EE+ + E+E++ Q+ + Sbjct: 554 KQEEKMWRQEEKMHDQEEKIREQEEKVWRQEEKIREQEEKIREQEEKIREQEEMTQEQEE 613 Query: 69 KYGLKKKEEKEAEEKAALEQPCEGSLTRPKKAIPAGCGDEEEEEEE 114 K G ++++ E EEK Q E + R ++ I E+EE+ Sbjct: 614 KMGEQEEKMCEQEEKM---QEQEEKMRRQEEKIREQEKKIREQEEK 656 Score = 32.3 bits (72), Expect = 0.12 Identities = 17/66 (25%), Positives = 41/66 (62%), Gaps = 2/66 (3%) Query: 23 EEEKDPDAQKKEEERQEALRQQEEERKAKHARMEAEREKVRQQIRDKYGLKKKEEKEAEE 82 +EEK ++K +E +E +++QEE+ + + ++ + EK+R+Q ++ +K+E+ +E Sbjct: 359 QEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQ--EEMMWEKEEKMRRQE 416 Query: 83 KAALEQ 88 + E+ Sbjct: 417 EMMWEK 422 Score = 31.2 bits (69), Expect = 0.26 Identities = 16/61 (26%), Positives = 35/61 (57%) Query: 23 EEEKDPDAQKKEEERQEALRQQEEERKAKHARMEAEREKVRQQIRDKYGLKKKEEKEAEE 82 E+E+ Q+++ RQE + ++EE+ + M E+E+ ++ + K+++ +E EE Sbjct: 386 EQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEE 445 Query: 83 K 83 K Sbjct: 446 K 446 Score = 31.2 bits (69), Expect = 0.26 Identities = 24/94 (25%), Positives = 50/94 (53%), Gaps = 4/94 (4%) Query: 23 EEEKDPDAQKKEEERQEALRQQEEERKAKHARMEAE--REKVRQQIRDKYGLKKKEEKEA 80 +EE + ++K E +E + +QE+ R+ + R E E RE+ ++Q ++ +++E+ Sbjct: 429 QEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIRE 488 Query: 81 EEKAALEQPCEGSLTRPKKAIPAGCGDEEEEEEE 114 +E+ EQ E + R ++ I EEE+ + Sbjct: 489 QEEKIREQ--EEKMWRQEEKIHEQEKIREEEKRQ 520 Score = 30.4 bits (67), Expect = 0.44 Identities = 23/78 (29%), Positives = 37/78 (47%), Gaps = 1/78 (1%) Query: 6 KQALGGATKDMGKMLGGEEEKDPDAQKKEEERQEALRQQEEERKAKHARMEAEREKVRQQ 65 +Q L +GK L K AQ +E E L QQ+EE+ + E E+ Q+ Sbjct: 321 QQQLQAEADHLGKELQSVSAK-LQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQE 379 Query: 66 IRDKYGLKKKEEKEAEEK 83 +K ++++ +E EEK Sbjct: 380 QEEKIREQEEKIREQEEK 397 Score = 30.0 bits (66), Expect = 0.58 Identities = 17/71 (23%), Positives = 38/71 (53%) Query: 18 KMLGGEEEKDPDAQKKEEERQEALRQQEEERKAKHARMEAEREKVRQQIRDKYGLKKKEE 77 KM EE+ +K E+ ++ RQ+E+ + + R E +R++ + R + ++++EE Sbjct: 478 KMWRQEEKIREQEEKIREQEEKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEE 537 Query: 78 KEAEEKAALEQ 88 +++ EQ Sbjct: 538 IWRQKEKIHEQ 548 Score = 29.6 bits (65), Expect = 0.76 Identities = 25/101 (24%), Positives = 50/101 (49%), Gaps = 11/101 (10%) Query: 25 EKDPDAQKKEE---ERQEALRQQEE-----ERKAKHARMEAEREKVRQQIR---DKYGLK 73 EK+ +++EE E++E +R+ EE E+ + E EK+R+Q + + + Sbjct: 421 EKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMW 480 Query: 74 KKEEKEAEEKAALEQPCEGSLTRPKKAIPAGCGDEEEEEEE 114 ++EEK E++ + + E + +K EEE+ +E Sbjct: 481 RQEEKIREQEEKIREQEEKMWRQEEKIHEQEKIREEEKRQE 521 >gi|78190492 retinitis pigmentosa GTPase regulator isoform C [Homo sapiens] Length = 1152 Score = 44.3 bits (103), Expect = 3e-05 Identities = 29/105 (27%), Positives = 55/105 (52%), Gaps = 13/105 (12%) Query: 21 GGEEE----KDPDAQKKEEERQEALRQQEEERKAKHARMEAEREKVRQQIRDKYGLKKKE 76 GGEEE ++ + ++EEE +E + +EE + + E E+E+ ++ ++ G ++K Sbjct: 730 GGEEEHGEGEEEEGDREEEEEKEG--EGKEEGEGEEVEGEREKEEGERKKEERAGKEEKG 787 Query: 77 EKEAEEKAALEQPCEGSLTRPKKA-------IPAGCGDEEEEEEE 114 E+E ++ E+ EG ++ + G G+ EEEEEE Sbjct: 788 EEEGDQGEGEEEETEGRGEEKEEGGEVEGGEVEEGKGEREEEEEE 832 Score = 39.7 bits (91), Expect = 7e-04 Identities = 31/103 (30%), Positives = 49/103 (47%), Gaps = 9/103 (8%) Query: 12 ATKDMGKMLGGEEEKDPDAQKKEEERQEALRQQEEERKAKHARMEAEREKVRQQIRDKYG 71 A K+ K GEE++ QK+ E+ + R QE E + E E E+ ++ ++ Sbjct: 697 AEKEEWKKRDGEEQE----QKEREQGHQKERNQEMEEGGEEEHGEGEEEEGDREEEEEKE 752 Query: 72 LKKKEEKEAEEKAALEQPCEGSLTRPKKAIPAGCGDEEEEEEE 114 + KEE E EE + EG + ++A G EE+ EEE Sbjct: 753 GEGKEEGEGEEVEGEREKEEGERKKEERA-----GKEEKGEEE 790 Score = 38.9 bits (89), Expect = 0.001 Identities = 29/94 (30%), Positives = 45/94 (47%), Gaps = 9/94 (9%) Query: 22 GEEEKDPDAQKKEEERQEALRQQEEERKAKHARMEAEREKVRQQIRDKYGLKKKEEKEAE 81 GEEE+ ++EE +E + E E + + E E +V ++ + G + EE+E E Sbjct: 981 GEEEEGEGEGEEEEGEEEGEEEGEGEEEGEGEGEEEEEGEVEGEVEGEEGEGEGEEEEGE 1040 Query: 82 EKA-ALEQPCEGSLTRPKKAIPAGCGDEEEEEEE 114 E+ E+ EG R + EEEEEEE Sbjct: 1041 EEGEEREKEGEGEENRRNR--------EEEEEEE 1066 Score = 36.2 bits (82), Expect = 0.008 Identities = 31/113 (27%), Positives = 50/113 (44%), Gaps = 12/113 (10%) Query: 11 GATKDMGKMLGGEEEKDPDAQKKE---------EERQEALRQQEEERKAKHARMEAEREK 61 G + G+ + GE EK+ +KKE EE + +EEE + + E E Sbjct: 755 GKEEGEGEEVEGEREKEEGERKKEERAGKEEKGEEEGDQGEGEEEETEGRGEEKEEGGEV 814 Query: 62 VRQQIRDKYGLKKKEEKEAEEKAALEQPCEGSLTRPKKAIPAGCGDEEEEEEE 114 ++ + G +++EE+E E + E+ EG + G G EEE EE Sbjct: 815 EGGEVEEGKGEREEEEEEGEGE---EEEGEGEEEEGEGEEEEGEGKGEEEGEE 864 Score = 35.8 bits (81), Expect = 0.011 Identities = 31/98 (31%), Positives = 48/98 (48%), Gaps = 4/98 (4%) Query: 17 GKMLGGEEEKDPDAQKKEEERQEALRQQEEERKAKHARMEAEREKVRQQIRDKYGLKKKE 76 GK GEEE D Q + EE + R +E+E + E E K ++ ++ G ++E Sbjct: 782 GKEEKGEEEGD---QGEGEEEETEGRGEEKEEGGEVEGGEVEEGKGEREEEEEEGEGEEE 838 Query: 77 EKEAEEKAALEQPCEGSLTRPKKAIPAGCGDEEEEEEE 114 E E EE+ + EG + ++ G G+EE EE E Sbjct: 839 EGEGEEEEGEGEEEEGE-GKGEEEGEEGEGEEEGEEGE 875 Score = 34.7 bits (78), Expect = 0.024 Identities = 26/93 (27%), Positives = 43/93 (46%) Query: 22 GEEEKDPDAQKKEEERQEALRQQEEERKAKHARMEAEREKVRQQIRDKYGLKKKEEKEAE 81 GEEE + + +++E E + +E E + + E E E + ++ G + EE+E E Sbjct: 904 GEEEGEGEGEEEEGEGKGEEEGEEGEGEGEEEEGEGEGEDGEGEGEEEEGEWEGEEEEGE 963 Query: 82 EKAALEQPCEGSLTRPKKAIPAGCGDEEEEEEE 114 + E EG + G G+ EEEE E Sbjct: 964 GEGEEEGEGEGEEGEGEGEEEEGEGEGEEEEGE 996 Score = 34.3 bits (77), Expect = 0.031 Identities = 24/110 (21%), Positives = 56/110 (50%), Gaps = 7/110 (6%) Query: 11 GATKDMGKMLGGEEEKDPDAQKKEEERQEALRQQEEERKAKHARMEAEREKVRQQIRDKY 70 G ++ G++ G E ++ + + +EEE +E ++E+E + + R E E+ + + Sbjct: 1013 GEEEEEGEVEGEVEGEEGEGEGEEEEGEEEGEEREKEGEGEENRRNREEEEEEEGKYQET 1072 Query: 71 GLKKKEEKEAEEKAALEQPCEGSL------TRPKKAIPAGCGDEEEEEEE 114 G ++ E ++ EE + + +GS+ T KK++ G+ +E+ + Sbjct: 1073 GEEENERQDGEEYKKVSK-IKGSVKYGKHKTYQKKSVTNTQGNGKEQRSK 1121 Score = 33.9 bits (76), Expect = 0.040 Identities = 30/105 (28%), Positives = 52/105 (49%), Gaps = 6/105 (5%) Query: 10 GGATKDMGKMLGGEEEKDPDAQKKEEERQEALRQQEEERKAKHARMEAEREKVRQQIRDK 69 G ++ G++ GGE E+ +++EEE E +EEE + + E E E+ + ++ Sbjct: 805 GEEKEEGGEVEGGEVEEGKGEREEEEEEGEG---EEEEGEGEEEEGEGEEEEGEGK-GEE 860 Query: 70 YGLKKKEEKEAEEKAALEQPCEGSLTRPKKAIPAGCGDEEEEEEE 114 G + + E+E EE + EG ++ G G+EEE E E Sbjct: 861 EGEEGEGEEEGEEGEGEGEEEEGEGEGEEEG--EGEGEEEEGEGE 903 Score = 33.1 bits (74), Expect = 0.069 Identities = 28/100 (28%), Positives = 46/100 (46%), Gaps = 10/100 (10%) Query: 22 GEEEKDPDAQKKEEERQEALRQQEEERKAKHARMEAEREKVRQQIRDKYGLKKKEEK--- 78 GE E++ + EEE E ++E E + + E E E+ + ++ G ++ EE+ Sbjct: 946 GEGEEEEGEWEGEEEEGEGEGEEEGEGEGEEGEGEGEEEEGEGEGEEEEGEEEGEEEGEG 1005 Query: 79 ----EAEEKAALEQPCEGSLTRPKKAIPAGCGDEEEEEEE 114 E E + E EG + + G G+EEE EEE Sbjct: 1006 EEEGEGEGEEEEEGEVEGEVEGEE---GEGEGEEEEGEEE 1042 Score = 32.7 bits (73), Expect = 0.089 Identities = 30/105 (28%), Positives = 49/105 (46%), Gaps = 3/105 (2%) Query: 11 GATKDMGKMLGGEEEKDPDAQKKEEERQEALRQQEEERKAKHARMEAEREKVRQQIRDKY 70 G + GK EEE++ + +++E E +E + EEE + E E E+ + + Sbjct: 816 GGEVEEGKGEREEEEEEGEGEEEEGEGEEEEGEGEEEE--GEGKGEEEGEEGEGEEEGEE 873 Query: 71 GLKKKEEKEAEEKAALEQPCEGSLTRPK-KAIPAGCGDEEEEEEE 114 G + EE+E E + E EG + + G G+ EEEE E Sbjct: 874 GEGEGEEEEGEGEGEEEGEGEGEEEEGEGEGEEEGEGEGEEEEGE 918 Score = 31.6 bits (70), Expect = 0.20 Identities = 29/104 (27%), Positives = 46/104 (44%), Gaps = 5/104 (4%) Query: 11 GATKDMGKMLGGEEEKDPDAQKKEEERQEALRQQEEERKAKHARMEAEREKVRQQIRDKY 70 G ++ G+ GEEE + + EEE E ++E E + + E E E+ + ++ Sbjct: 856 GKGEEEGEEGEGEEEGEEGEGEGEEEEGEGEGEEEGEGEGEEEEGEGEGEEEGEGEGEEE 915 Query: 71 GLKKKEEKEAEEKAALEQPCEGSLTRPKKAIPAGCGDEEEEEEE 114 + K E+E EE EG + G G+ EEEE E Sbjct: 916 EGEGKGEEEGEEGEG-----EGEEEEGEGEGEDGEGEGEEEEGE 954 Score = 31.2 bits (69), Expect = 0.26 Identities = 30/101 (29%), Positives = 51/101 (50%), Gaps = 16/101 (15%) Query: 14 KDMGKMLGGEEEKDPDAQKKEEERQEALRQQEEERKAKHARMEAEREKVRQQIRDKYGLK 73 KD G+ GE E+ + +K+ E++E ++ EE++ K ERE+ Q+ R+ Sbjct: 679 KDKGR---GEMERPGEGEKELAEKEEWKKRDGEEQEQK------EREQGHQKERN----- 724 Query: 74 KKEEKEAEEKAALEQPCEGSLTRPKKAIPAGCGDEEEEEEE 114 ++ E+ EE+ + EG R ++ G G EE E EE Sbjct: 725 QEMEEGGEEEHGEGEEEEGD--REEEEEKEGEGKEEGEGEE 763 Score = 31.2 bits (69), Expect = 0.26 Identities = 27/93 (29%), Positives = 44/93 (47%), Gaps = 1/93 (1%) Query: 22 GEEEKDPDAQKKEEERQEALRQQEEERKAKHARMEAEREKVRQQIRDKYGLKKKEEKEAE 81 GE E++ K EEE +E +EE + + E E E ++ + G +++ E E E Sbjct: 847 GEGEEEEGEGKGEEEGEEG-EGEEEGEEGEGEGEEEEGEGEGEEEGEGEGEEEEGEGEGE 905 Query: 82 EKAALEQPCEGSLTRPKKAIPAGCGDEEEEEEE 114 E+ E E + ++ G G+ EEEE E Sbjct: 906 EEGEGEGEEEEGEGKGEEEGEEGEGEGEEEEGE 938 Score = 30.8 bits (68), Expect = 0.34 Identities = 25/96 (26%), Positives = 43/96 (44%), Gaps = 11/96 (11%) Query: 21 GGEEEKDPDAQKKEEE--RQEALRQQEEERKAKHARMEAEREKVRQQIRDKYGLKKKEEK 78 G E +D + +K E++ R E R E E++ +R+ Q+ +++ +KE Sbjct: 665 GAEHWQDEEREKGEKDKGRGEMERPGEGEKELAEKEEWKKRDGEEQEQKEREQGHQKERN 724 Query: 79 EAEEKAALEQPCEGSLTRPKKAIPAGCGDEEEEEEE 114 + E+ E+ EG GD EEEEE+ Sbjct: 725 QEMEEGGEEEHGEGEEEE---------GDREEEEEK 751 Score = 30.8 bits (68), Expect = 0.34 Identities = 30/104 (28%), Positives = 47/104 (45%), Gaps = 14/104 (13%) Query: 17 GKMLGGEEEKDPDAQ----KKEEERQEALRQQEEERKAKHARMEAEREKVRQQIRDKYGL 72 G+ G EEE + + + + EEE E ++EE E E E+ + ++ G Sbjct: 928 GEGEGEEEEGEGEGEDGEGEGEEEEGEWEGEEEEGEGEGEEEGEGEGEEGEGEGEEEEGE 987 Query: 73 KKKEEKEAEEKAALEQPCEGSLTRPKKAIPAGCGDEEEEEEESI 116 + EE+E EE+ E+ EG G G+ EEEEE + Sbjct: 988 GEGEEEEGEEEG--EEEGEGE--------EEGEGEGEEEEEGEV 1021 Score = 28.1 bits (61), Expect = 2.2 Identities = 24/102 (23%), Positives = 44/102 (43%), Gaps = 10/102 (9%) Query: 10 GGATKDMGKMLGGEEEKDPDAQ--KKEEERQEALRQQEEERKAKHARMEAEREKVRQQIR 67 G + G+ G EEE + + + +KE E +E R +EEE + + E E+ +Q Sbjct: 1023 GEVEGEEGEGEGEEEEGEEEGEEREKEGEGEENRRNREEEEEEEGKYQETGEEENERQDG 1082 Query: 68 DKY--------GLKKKEEKEAEEKAALEQPCEGSLTRPKKAI 101 ++Y +K + K ++K+ G R K + Sbjct: 1083 EEYKKVSKIKGSVKYGKHKTYQKKSVTNTQGNGKEQRSKMPV 1124 Score = 26.2 bits (56), Expect = 8.4 Identities = 24/104 (23%), Positives = 45/104 (43%), Gaps = 11/104 (10%) Query: 22 GEEEKDPDAQKKEEERQEALRQQEEERKAKHARMEAEREKVRQQIRDKYGL--KKKEEKE 79 GE E++ + + +EEE E + E E E E+ ++ ++ G ++ E+E Sbjct: 1003 GEGEEEGEGEGEEEEEGEVEGEVEGEEGEGEGEEEEGEEEGEEREKEGEGEENRRNREEE 1062 Query: 80 AEEKAALEQPCEGSLTRPKKAIPAGCGDEEEEEEESILDTVLKY 123 EE+ ++ E R D EE ++ S + +KY Sbjct: 1063 EEEEGKYQETGEEENERQ---------DGEEYKKVSKIKGSVKY 1097 >gi|157738649 neurofilament, medium polypeptide 150kDa isoform 1 [Homo sapiens] Length = 916 Score = 43.9 bits (102), Expect = 4e-05 Identities = 31/111 (27%), Positives = 61/111 (54%), Gaps = 6/111 (5%) Query: 5 MKQALGGATKDMGKMLGGEEEKDPDAQKKEEERQEALRQQEEERKAKHARMEAEREKVRQ 64 M++AL T+++ + +EEK A++KEEE + +EEE AK + ++A +V++ Sbjct: 469 MEEALTAITEELAVSM--KEEKKEAAEEKEEEPEA----EEEEVAAKKSPVKATAPEVKE 522 Query: 65 QIRDKYGLKKKEEKEAEEKAALEQPCEGSLTRPKKAIPAGCGDEEEEEEES 115 + +K + +EE+E E++ A E + + + G++EE E E+ Sbjct: 523 EEGEKEEEEGQEEEEEEDEGAKSDQAEEGGSEKEGSSEKEEGEQEEGETEA 573 Score = 37.0 bits (84), Expect = 0.005 Identities = 25/94 (26%), Positives = 48/94 (51%), Gaps = 3/94 (3%) Query: 22 GEEEKDPDAQKKEEERQEALRQQEEERKAKHARMEAEREKVRQQIRDKYGLKKKEEKEAE 81 GE+E++ + Q++EEE E + + E +E+E+ Q+ + + EE EA+ Sbjct: 525 GEKEEE-EGQEEEEEEDEGAKSDQAEEGGSEKEGSSEKEEGEQEEGETEAEAEGEEAEAK 583 Query: 82 EKAALEQPCEGSLTRPKKAIPAGCGDEEEEEEES 115 E+ +E+ E T K+ + A E+ E+ +S Sbjct: 584 EEKKVEEKSEEVAT--KEELVADAKVEKPEKAKS 615 Score = 35.4 bits (80), Expect = 0.014 Identities = 24/85 (28%), Positives = 41/85 (48%), Gaps = 8/85 (9%) Query: 21 GGEEEKDPDAQKKEEERQEALRQQE-----EERKAKHARMEAEREKVRQQIRDKYGLKKK 75 G EEE++ D K ++ +E ++E EE + + EAE E + +++ KK Sbjct: 532 GQEEEEEEDEGAKSDQAEEGGSEKEGSSEKEEGEQEEGETEAEAEGEEAEAKEE---KKV 588 Query: 76 EEKEAEEKAALEQPCEGSLTRPKKA 100 EEK E E + + +P+KA Sbjct: 589 EEKSEEVATKEELVADAKVEKPEKA 613 Score = 34.7 bits (78), Expect = 0.024 Identities = 25/99 (25%), Positives = 45/99 (45%), Gaps = 2/99 (2%) Query: 11 GATKDMGKMLGGEEEKDPDAQKKEEERQEALRQQEEERKAKHARMEAEREKVRQQIRDKY 70 GA D + G EK+ ++K+E E++E + E E + A+ E + E+ +++ K Sbjct: 542 GAKSDQAEE--GGSEKEGSSEKEEGEQEEGETEAEAEGEEAEAKEEKKVEEKSEEVATKE 599 Query: 71 GLKKKEEKEAEEKAALEQPCEGSLTRPKKAIPAGCGDEE 109 L + E EKA P + K +P +E+ Sbjct: 600 ELVADAKVEKPEKAKSPVPKSPVEEKGKSPVPKSPVEEK 638 Score = 32.0 bits (71), Expect = 0.15 Identities = 25/98 (25%), Positives = 45/98 (45%), Gaps = 12/98 (12%) Query: 22 GEEEKDPDAQKKEEERQEALRQQEEERK----AKHARMEAEREKVRQQIRDKYGLKKKEE 77 GE++++ + + KE ++E + ++EE+ K K A + E V + + +K E Sbjct: 699 GEQKEEEEKEVKEAPKEEKVEKKEEKPKDVPEKKKAESPVKEEAVAEVVTITKSVKVHLE 758 Query: 78 KEAEEKAALEQPCEGSLTRPKKAIPAGCGDEEEEEEES 115 KE +E EG + +K G+ EEE S Sbjct: 759 KETKE--------EGKPLQQEKEKEKAGGEGGSEEEGS 788 Score = 30.8 bits (68), Expect = 0.34 Identities = 24/99 (24%), Positives = 49/99 (49%), Gaps = 2/99 (2%) Query: 23 EEEKDPDAQKKEEERQEA-LRQQEEERKAKHARMEAEREKVRQQIRDKYGLKKKEEKEAE 81 E+ K P + EE+ ++ + + E KAK ++ E+ + + G +K+EE++ Sbjct: 650 EKGKSPVPKSPVEEKGKSPVSKSPVEEKAKSPVPKSPVEEAKSKAEVGKGEQKEEEEKEV 709 Query: 82 EKAALEQPCEGSLTRPKKAIPAGCGDEEEEEEESILDTV 120 ++A E+ E +PK +P E +EE++ + V Sbjct: 710 KEAPKEEKVEKKEEKPKD-VPEKKKAESPVKEEAVAEVV 747 Score = 30.4 bits (67), Expect = 0.44 Identities = 28/102 (27%), Positives = 50/102 (49%), Gaps = 5/102 (4%) Query: 23 EEEKDPDAQKKEEERQEALRQQEEERKAKHARMEAEREKVRQQIRDKYGLKKKEEKEAEE 82 +EE P Q+KE+E+ EEE K A+ + +E + + + K++ E+E +E Sbjct: 762 KEEGKPLQQEKEKEKAGGEGGSEEEGSDKGAK-GSRKEDI--AVNGEVEGKEEVEQETKE 818 Query: 83 KAALEQPCEGSLTRPKKAIPAG--CGDEEEEEEESILDTVLK 122 K + + +G +T PA G ++ EE+ + TV K Sbjct: 819 KGSGREEEKGVVTNGLDLSPADEKKGGDKSEEKVVVTKTVEK 860 Score = 29.6 bits (65), Expect = 0.76 Identities = 25/97 (25%), Positives = 41/97 (42%), Gaps = 18/97 (18%) Query: 23 EEEKDPDAQKKEEERQEALRQQ-----EEERKAKHARMEAEREKVRQQIRDKYGLKKKEE 77 EE K D + + EE A+ ++ +EE+K E E E +++ K K Sbjct: 458 EETKVEDEKSEMEEALTAITEELAVSMKEEKKEAAEEKEEEPEAEEEEVAAKKSPVKATA 517 Query: 78 KEAEEKAALEQPCEGSLTRPKKAIPAGCGDEEEEEEE 114 E +E+ ++ EG +EEEEE+E Sbjct: 518 PEVKEEEGEKEEEEGQ-------------EEEEEEDE 541 Score = 28.1 bits (61), Expect = 2.2 Identities = 20/88 (22%), Positives = 37/88 (42%) Query: 22 GEEEKDPDAQKKEEERQEALRQQEEERKAKHARMEAEREKVRQQIRDKYGLKKKEEKEAE 81 GEE + + +K EE+ +E ++E AK + E + V + ++ G + E Sbjct: 577 GEEAEAKEEKKVEEKSEEVATKEELVADAKVEKPEKAKSPVPKSPVEEKGKSPVPKSPVE 636 Query: 82 EKAALEQPCEGSLTRPKKAIPAGCGDEE 109 EK P + K +P +E+ Sbjct: 637 EKGKSPVPKSPVEEKGKSPVPKSPVEEK 664 Score = 27.7 bits (60), Expect = 2.9 Identities = 21/93 (22%), Positives = 39/93 (41%) Query: 23 EEEKDPDAQKKEEERQEALRQQEEERKAKHARMEAEREKVRQQIRDKYGLKKKEEKEAEE 82 E E++ A KK + A +EEE + + + E E+ + + + EKE Sbjct: 500 EAEEEEVAAKKSPVKATAPEVKEEEGEKEEEEGQEEEEEEDEGAKSDQAEEGGSEKEGSS 559 Query: 83 KAALEQPCEGSLTRPKKAIPAGCGDEEEEEEES 115 + + EG + A +E++ EE+S Sbjct: 560 EKEEGEQEEGETEAEAEGEEAEAKEEKKVEEKS 592 >gi|157738641 neurofilament, medium polypeptide 150kDa isoform 2 [Homo sapiens] Length = 540 Score = 43.9 bits (102), Expect = 4e-05 Identities = 31/111 (27%), Positives = 61/111 (54%), Gaps = 6/111 (5%) Query: 5 MKQALGGATKDMGKMLGGEEEKDPDAQKKEEERQEALRQQEEERKAKHARMEAEREKVRQ 64 M++AL T+++ + +EEK A++KEEE + +EEE AK + ++A +V++ Sbjct: 93 MEEALTAITEELAVSM--KEEKKEAAEEKEEEPEA----EEEEVAAKKSPVKATAPEVKE 146 Query: 65 QIRDKYGLKKKEEKEAEEKAALEQPCEGSLTRPKKAIPAGCGDEEEEEEES 115 + +K + +EE+E E++ A E + + + G++EE E E+ Sbjct: 147 EEGEKEEEEGQEEEEEEDEGAKSDQAEEGGSEKEGSSEKEEGEQEEGETEA 197 Score = 37.0 bits (84), Expect = 0.005 Identities = 25/94 (26%), Positives = 48/94 (51%), Gaps = 3/94 (3%) Query: 22 GEEEKDPDAQKKEEERQEALRQQEEERKAKHARMEAEREKVRQQIRDKYGLKKKEEKEAE 81 GE+E++ + Q++EEE E + + E +E+E+ Q+ + + EE EA+ Sbjct: 149 GEKEEE-EGQEEEEEEDEGAKSDQAEEGGSEKEGSSEKEEGEQEEGETEAEAEGEEAEAK 207 Query: 82 EKAALEQPCEGSLTRPKKAIPAGCGDEEEEEEES 115 E+ +E+ E T K+ + A E+ E+ +S Sbjct: 208 EEKKVEEKSEEVAT--KEELVADAKVEKPEKAKS 239 Score = 35.4 bits (80), Expect = 0.014 Identities = 24/85 (28%), Positives = 41/85 (48%), Gaps = 8/85 (9%) Query: 21 GGEEEKDPDAQKKEEERQEALRQQE-----EERKAKHARMEAEREKVRQQIRDKYGLKKK 75 G EEE++ D K ++ +E ++E EE + + EAE E + +++ KK Sbjct: 156 GQEEEEEEDEGAKSDQAEEGGSEKEGSSEKEEGEQEEGETEAEAEGEEAEAKEE---KKV 212 Query: 76 EEKEAEEKAALEQPCEGSLTRPKKA 100 EEK E E + + +P+KA Sbjct: 213 EEKSEEVATKEELVADAKVEKPEKA 237 Score = 34.7 bits (78), Expect = 0.024 Identities = 25/99 (25%), Positives = 45/99 (45%), Gaps = 2/99 (2%) Query: 11 GATKDMGKMLGGEEEKDPDAQKKEEERQEALRQQEEERKAKHARMEAEREKVRQQIRDKY 70 GA D + G EK+ ++K+E E++E + E E + A+ E + E+ +++ K Sbjct: 166 GAKSDQAEE--GGSEKEGSSEKEEGEQEEGETEAEAEGEEAEAKEEKKVEEKSEEVATKE 223 Query: 71 GLKKKEEKEAEEKAALEQPCEGSLTRPKKAIPAGCGDEE 109 L + E EKA P + K +P +E+ Sbjct: 224 ELVADAKVEKPEKAKSPVPKSPVEEKGKSPVPKSPVEEK 262 Score = 32.0 bits (71), Expect = 0.15 Identities = 25/98 (25%), Positives = 45/98 (45%), Gaps = 12/98 (12%) Query: 22 GEEEKDPDAQKKEEERQEALRQQEEERK----AKHARMEAEREKVRQQIRDKYGLKKKEE 77 GE++++ + + KE ++E + ++EE+ K K A + E V + + +K E Sbjct: 323 GEQKEEEEKEVKEAPKEEKVEKKEEKPKDVPEKKKAESPVKEEAVAEVVTITKSVKVHLE 382 Query: 78 KEAEEKAALEQPCEGSLTRPKKAIPAGCGDEEEEEEES 115 KE +E EG + +K G+ EEE S Sbjct: 383 KETKE--------EGKPLQQEKEKEKAGGEGGSEEEGS 412 Score = 30.8 bits (68), Expect = 0.34 Identities = 24/99 (24%), Positives = 49/99 (49%), Gaps = 2/99 (2%) Query: 23 EEEKDPDAQKKEEERQEA-LRQQEEERKAKHARMEAEREKVRQQIRDKYGLKKKEEKEAE 81 E+ K P + EE+ ++ + + E KAK ++ E+ + + G +K+EE++ Sbjct: 274 EKGKSPVPKSPVEEKGKSPVSKSPVEEKAKSPVPKSPVEEAKSKAEVGKGEQKEEEEKEV 333 Query: 82 EKAALEQPCEGSLTRPKKAIPAGCGDEEEEEEESILDTV 120 ++A E+ E +PK +P E +EE++ + V Sbjct: 334 KEAPKEEKVEKKEEKPKD-VPEKKKAESPVKEEAVAEVV 371 Score = 30.4 bits (67), Expect = 0.44 Identities = 28/102 (27%), Positives = 50/102 (49%), Gaps = 5/102 (4%) Query: 23 EEEKDPDAQKKEEERQEALRQQEEERKAKHARMEAEREKVRQQIRDKYGLKKKEEKEAEE 82 +EE P Q+KE+E+ EEE K A+ + +E + + + K++ E+E +E Sbjct: 386 KEEGKPLQQEKEKEKAGGEGGSEEEGSDKGAK-GSRKEDI--AVNGEVEGKEEVEQETKE 442 Query: 83 KAALEQPCEGSLTRPKKAIPAG--CGDEEEEEEESILDTVLK 122 K + + +G +T PA G ++ EE+ + TV K Sbjct: 443 KGSGREEEKGVVTNGLDLSPADEKKGGDKSEEKVVVTKTVEK 484 Score = 29.6 bits (65), Expect = 0.76 Identities = 25/97 (25%), Positives = 41/97 (42%), Gaps = 18/97 (18%) Query: 23 EEEKDPDAQKKEEERQEALRQQ-----EEERKAKHARMEAEREKVRQQIRDKYGLKKKEE 77 EE K D + + EE A+ ++ +EE+K E E E +++ K K Sbjct: 82 EETKVEDEKSEMEEALTAITEELAVSMKEEKKEAAEEKEEEPEAEEEEVAAKKSPVKATA 141 Query: 78 KEAEEKAALEQPCEGSLTRPKKAIPAGCGDEEEEEEE 114 E +E+ ++ EG +EEEEE+E Sbjct: 142 PEVKEEEGEKEEEEGQ-------------EEEEEEDE 165 Score = 28.1 bits (61), Expect = 2.2 Identities = 20/88 (22%), Positives = 37/88 (42%) Query: 22 GEEEKDPDAQKKEEERQEALRQQEEERKAKHARMEAEREKVRQQIRDKYGLKKKEEKEAE 81 GEE + + +K EE+ +E ++E AK + E + V + ++ G + E Sbjct: 201 GEEAEAKEEKKVEEKSEEVATKEELVADAKVEKPEKAKSPVPKSPVEEKGKSPVPKSPVE 260 Query: 82 EKAALEQPCEGSLTRPKKAIPAGCGDEE 109 EK P + K +P +E+ Sbjct: 261 EKGKSPVPKSPVEEKGKSPVPKSPVEEK 288 Score = 27.7 bits (60), Expect = 2.9 Identities = 21/93 (22%), Positives = 39/93 (41%) Query: 23 EEEKDPDAQKKEEERQEALRQQEEERKAKHARMEAEREKVRQQIRDKYGLKKKEEKEAEE 82 E E++ A KK + A +EEE + + + E E+ + + + EKE Sbjct: 124 EAEEEEVAAKKSPVKATAPEVKEEEGEKEEEEGQEEEEEEDEGAKSDQAEEGGSEKEGSS 183 Query: 83 KAALEQPCEGSLTRPKKAIPAGCGDEEEEEEES 115 + + EG + A +E++ EE+S Sbjct: 184 EKEEGEQEEGETEAEAEGEEAEAKEEKKVEEKS 216 >gi|239508778 PREDICTED: hypothetical protein, partial [Homo sapiens] Length = 123 Score = 43.5 bits (101), Expect = 5e-05 Identities = 27/95 (28%), Positives = 53/95 (55%), Gaps = 4/95 (4%) Query: 24 EEKDPDAQKKEEERQEALRQQEEERKAKHARMEAEREKVRQQIRDKYGLKK----KEEKE 79 EE++ K++E+R+E +++E+++K K E+E+ ++ + K KK +EE+E Sbjct: 20 EEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEKKRKRKRKKKKEEEEREEEE 79 Query: 80 AEEKAALEQPCEGSLTRPKKAIPAGCGDEEEEEEE 114 EE+ E+ + R KK +EEEE+++ Sbjct: 80 EEEEEEKEEEEKEEGRRRKKKKKRRRKEEEEEKKK 114 Score = 43.1 bits (100), Expect = 7e-05 Identities = 25/92 (27%), Positives = 48/92 (52%), Gaps = 18/92 (19%) Query: 23 EEEKDPDAQKKEEERQEALRQQEEERKAKHARMEAEREKVRQQIRDKYGLKKKEEKEAEE 82 E E+ + ++KE +R+E +++ +E++ K E E+ K +++ K K+K++KE EE Sbjct: 15 ETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEKKRKRKRKKKKEEEE 74 Query: 83 KAALEQPCEGSLTRPKKAIPAGCGDEEEEEEE 114 + E+ +EEEE+EE Sbjct: 75 REEEEE------------------EEEEEKEE 88 Score = 43.1 bits (100), Expect = 7e-05 Identities = 28/97 (28%), Positives = 57/97 (58%), Gaps = 8/97 (8%) Query: 23 EEEKDPDAQKKEEERQEALRQQEEERKAKHA-----RMEAEREKVRQQIRDKYGLKKKEE 77 EEEK+ K++E+R+E +++E+++K K + E E+++ R++ + K +++EE Sbjct: 22 EEEKEG---KRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEKKRKRKRKKKKEEEEREEE 78 Query: 78 KEAEEKAALEQPCEGSLTRPKKAIPAGCGDEEEEEEE 114 +E EE+ E+ E R KK +EEE++++ Sbjct: 79 EEEEEEEKEEEEKEEGRRRKKKKKRRRKEEEEEKKKK 115 Score = 42.7 bits (99), Expect = 9e-05 Identities = 31/91 (34%), Positives = 45/91 (49%), Gaps = 9/91 (9%) Query: 26 KDPDAQKKEEERQEALRQQEEERKAKHARMEAEREKVRQQIRDKYG--LKKKEEKEAEEK 83 K +KKE E E + EEE + + R E +EK +++ + K +K++EKE EEK Sbjct: 1 KKKKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEK 60 Query: 84 AALEQPCEGSLTRPKKAIPAGCGDEEEEEEE 114 + R KK +EEEEEEE Sbjct: 61 KRKRK-------RKKKKEEEEREEEEEEEEE 84 Score = 41.2 bits (95), Expect = 3e-04 Identities = 22/71 (30%), Positives = 46/71 (64%), Gaps = 1/71 (1%) Query: 13 TKDMGKMLGGEEEKDPDAQKKEEERQEALRQQEEERKAKHARMEAEREKVRQQIRDKYGL 72 TK+ K EEE+ +K++++++E R++EEE + + + E E+E+ R++ + K Sbjct: 46 TKETEKRKEKEEEEKKRKRKRKKKKEEEEREEEEEEE-EEEKEEEEKEEGRRRKKKKKRR 104 Query: 73 KKKEEKEAEEK 83 +K+EE+E ++K Sbjct: 105 RKEEEEEKKKK 115 Score = 35.8 bits (81), Expect = 0.011 Identities = 16/52 (30%), Positives = 32/52 (61%) Query: 23 EEEKDPDAQKKEEERQEALRQQEEERKAKHARMEAEREKVRQQIRDKYGLKK 74 EEE++ + +++EEE++E +++ RK K R E E+ +++ R + KK Sbjct: 72 EEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEEEEKKKKRRRKTKKK 123 Score = 33.1 bits (74), Expect = 0.069 Identities = 15/61 (24%), Positives = 38/61 (62%), Gaps = 2/61 (3%) Query: 23 EEEKDPDAQKKEEERQEALRQQEEERKAKHARMEAEREKVRQQIRDKYGLKKKEEKEAEE 82 + +K + +++EEE +E ++EEE K + R + ++++ R++ ++ KKK ++ ++ Sbjct: 65 KRKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEEEE--KKKKRRRKTKK 122 Query: 83 K 83 K Sbjct: 123 K 123 >gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo sapiens] Length = 750 Score = 43.1 bits (100), Expect = 7e-05 Identities = 24/95 (25%), Positives = 56/95 (58%), Gaps = 6/95 (6%) Query: 23 EEEKDPDAQKKEEERQEALRQQEEERKAKHARMEAEREKVRQQ---IRDKYGLKKKEEKE 79 +EEK + ++K ++E +R+QEE+R+ + +M + EK+R+Q I+++ +++E++ Sbjct: 575 QEEKIREQEEKVWRQEEKIREQEEKRQEQEEKMWKQEEKIREQEEKIQEQEEKIREQEEK 634 Query: 80 AEEKAALEQPCEGSLTRPKKAIPAGCGDEEEEEEE 114 E+ + Q E + ++ + C EE+ +E+ Sbjct: 635 IREQEEMTQEQEEKMGEQEEKM---CEQEEKMQEQ 666 Score = 42.0 bits (97), Expect = 1e-04 Identities = 22/79 (27%), Positives = 51/79 (64%), Gaps = 6/79 (7%) Query: 13 TKDMGKMLGGEEEKDPDAQKKEEERQEALRQQEEERKAKHARMEAEREKVRQQIRDKYGL 72 T++ + +G +EEK + ++K +E++E + +QEE+ + + ++ + EK+R+Q + + Sbjct: 642 TQEQEEKMGEQEEKMCEQEEKMQEQEETMWRQEEKIREQEKKIREQEEKIREQ---EEMM 698 Query: 73 KKKEEKEAEEKAALEQPCE 91 +++EEK E++ E+ CE Sbjct: 699 QEQEEKMWEQE---EKMCE 714 Score = 39.7 bits (91), Expect = 7e-04 Identities = 23/92 (25%), Positives = 52/92 (56%), Gaps = 7/92 (7%) Query: 23 EEEKDPDAQKKEEERQEALRQQEEERKAKHARMEAEREKVRQQIRDKYGLKKKEEKEAEE 82 +EE + ++K E++E + +QEE+ + + M + EK+R+Q + ++++EEK E+ Sbjct: 638 QEEMTQEQEEKMGEQEEKMCEQEEKMQEQEETMWRQEEKIREQEKK---IREQEEKIREQ 694 Query: 83 KAALEQPCEGSLTRPKKAIPAGCGDEEEEEEE 114 + +++ E + +K C EE+ +E+ Sbjct: 695 EEMMQEQEEKMWEQEEKM----CEQEEKMQEQ 722 Score = 38.1 bits (87), Expect = 0.002 Identities = 21/70 (30%), Positives = 41/70 (58%), Gaps = 4/70 (5%) Query: 23 EEEKDPDAQKKEEERQEALRQQEEERKAKHARMEAEREKVRQQ----IRDKYGLKKKEEK 78 +EEK + +KK E++E +R+QEE + + +M + EK+ +Q + ++++EEK Sbjct: 673 QEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEK 732 Query: 79 EAEEKAALEQ 88 E++ L Q Sbjct: 733 MWEQEVRLRQ 742 Score = 37.7 bits (86), Expect = 0.003 Identities = 22/74 (29%), Positives = 45/74 (60%), Gaps = 8/74 (10%) Query: 23 EEEKDPDAQKKEEE------RQEALRQQEEERKAKHARMEAEREKVRQQ--IRDKYGLKK 74 EEEK + +K++E+ ++E +R+QEE+ + + +M + EK+ +Q IR++ ++ Sbjct: 415 EEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQE 474 Query: 75 KEEKEAEEKAALEQ 88 +EE +E+ EQ Sbjct: 475 QEEMWRQEEKIHEQ 488 Score = 37.0 bits (84), Expect = 0.005 Identities = 29/97 (29%), Positives = 52/97 (53%), Gaps = 15/97 (15%) Query: 25 EKDPDAQKKEE---ERQEALRQQEEERKAKHARMEAEREKVRQQ--IRDKYGLKKKEEKE 79 EK+ +++EE E++E +R+QEE K ++ EK+ +Q IR++ +++EEK Sbjct: 360 EKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKI 419 Query: 80 AEEKAALEQPCEGSLTRPKKAIPAGCGDEEEEEEESI 116 E++ EQ E + R ++ I E+EE I Sbjct: 420 REQEKRQEQ--EAKMWRQEEKI--------REQEEKI 446 Score = 36.2 bits (82), Expect = 0.008 Identities = 19/65 (29%), Positives = 40/65 (61%), Gaps = 2/65 (3%) Query: 24 EEKDPDAQKKEEERQEALRQQEEERKAKHARMEAEREKVRQQIRDKYGLKKKEEKEAEEK 83 EEK + ++K E++E +R+QEE+ + + M + EK+R+Q ++ +K+E+ +E+ Sbjct: 313 EEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQ--EEMMWEKEEKMRRQEE 370 Query: 84 AALEQ 88 E+ Sbjct: 371 MMWEK 375 Score = 36.2 bits (82), Expect = 0.008 Identities = 26/92 (28%), Positives = 52/92 (56%), Gaps = 11/92 (11%) Query: 23 EEEKDPDAQKKEEERQEALRQQEEERKAKHARMEAEREKVRQQIRDKYGLKKKEEKEAEE 82 +EEK + ++K +E++E +R+QEE+ + E+E++ Q+ +K G ++++ E EE Sbjct: 610 QEEKIREQEEKIQEQEEKIREQEEKIR--------EQEEMTQEQEEKMGEQEEKMCEQEE 661 Query: 83 KAALEQPCEGSLTRPKKAIPAGCGDEEEEEEE 114 K Q E ++ R ++ I E+EE+ Sbjct: 662 KM---QEQEETMWRQEEKIREQEKKIREQEEK 690 Score = 35.4 bits (80), Expect = 0.014 Identities = 25/91 (27%), Positives = 50/91 (54%), Gaps = 3/91 (3%) Query: 23 EEEKDPDAQKKEEERQEALRQQEEERKAKHARMEAEREKVRQQIRDKYGLKKKEEKEAEE 82 EEEK + + K ++E +R+QEE+ + ++ + EK RQ+ +K + K+EEK E+ Sbjct: 561 EEEKRQEQEDKMWRQEEKIREQEEKVWRQEEKIREQEEK-RQEQEEK--MWKQEEKIREQ 617 Query: 83 KAALEQPCEGSLTRPKKAIPAGCGDEEEEEE 113 + +++ E + +K +E+EE+ Sbjct: 618 EEKIQEQEEKIREQEEKIREQEEMTQEQEEK 648 Score = 35.4 bits (80), Expect = 0.014 Identities = 19/72 (26%), Positives = 42/72 (58%), Gaps = 4/72 (5%) Query: 14 KDMGKMLGGEEEKDPDAQKKEEERQEALRQQEEERKAKHARMEAEREKVRQQ----IRDK 69 ++ K + +EEK + ++ +E++E + +QEE+ + +M+ + EK+R+Q + Sbjct: 678 REQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQE 737 Query: 70 YGLKKKEEKEAE 81 L+++EEK E Sbjct: 738 VRLRQQEEKMQE 749 Score = 35.0 bits (79), Expect = 0.018 Identities = 24/77 (31%), Positives = 46/77 (59%), Gaps = 13/77 (16%) Query: 25 EKDPDAQKKEE---ERQEALRQQEE---ERKAKHARME----AEREKVR---QQIRDKYG 71 EK+ +++EE E++E +R+QEE E++ K R E + EK+R +++ ++ Sbjct: 346 EKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEK 405 Query: 72 LKKKEEKEAEEKAALEQ 88 ++++EEK EE+ EQ Sbjct: 406 IREQEEKRQEEEKIREQ 422 Score = 35.0 bits (79), Expect = 0.018 Identities = 19/66 (28%), Positives = 39/66 (59%), Gaps = 4/66 (6%) Query: 23 EEEKDPDAQKKEEERQEALRQQEEERKAKHARMEAEREKVRQQIRDKYGLKKKEEKEAEE 82 +EEK ++K ++E +R+QEE+ + + +M + EK+R+Q + ++EEK E+ Sbjct: 501 QEEKIRKQEEKVWRQEEKIREQEEKIREQEEKMWRQEEKIREQEE----MWREEEKMHEQ 556 Query: 83 KAALEQ 88 + E+ Sbjct: 557 EKIWEE 562 Score = 34.3 bits (77), Expect = 0.031 Identities = 20/70 (28%), Positives = 41/70 (58%), Gaps = 4/70 (5%) Query: 23 EEEKDPDAQKKEEERQEALRQQEEERKAKHARMEAEREKVRQQ----IRDKYGLKKKEEK 78 E+E+ ++K E++E +R+QEE+ + ++ + EK+R+Q R + ++++EE Sbjct: 487 EQEEIWRQKEKMHEQEEKIRKQEEKVWRQEEKIREQEEKIREQEEKMWRQEEKIREQEEM 546 Query: 79 EAEEKAALEQ 88 EE+ EQ Sbjct: 547 WREEEKMHEQ 556 Score = 33.9 bits (76), Expect = 0.040 Identities = 22/66 (33%), Positives = 40/66 (60%), Gaps = 4/66 (6%) Query: 18 KMLGGEEEKDPDAQKKEEERQEALRQQEEERKAKHARMEAEREKVRQQIRDKYGLKKKEE 77 +M+ +EEK + ++K E QE +R+QEE+R+ + E E+ RQ+ K ++++ Sbjct: 384 EMMWEKEEKIRELEEKMHE-QEKIREQEEKRQEEEKIREQEK---RQEQEAKMWRQEEKI 439 Query: 78 KEAEEK 83 +E EEK Sbjct: 440 REQEEK 445 Score = 33.5 bits (75), Expect = 0.052 Identities = 25/75 (33%), Positives = 45/75 (60%), Gaps = 10/75 (13%) Query: 23 EEEKDPDAQKKEEERQEALRQQE--EERKAKHARME----AEREKVRQQIRDKYGLKKK- 75 E+EK + ++K +E +E +R+QE +E++AK R E + EK+R+Q + + ++K Sbjct: 402 EQEKIREQEEKRQE-EEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKI 460 Query: 76 --EEKEAEEKAALEQ 88 +EK EE+ EQ Sbjct: 461 HEQEKIREEEKRQEQ 475 Score = 33.5 bits (75), Expect = 0.052 Identities = 20/65 (30%), Positives = 39/65 (60%), Gaps = 5/65 (7%) Query: 23 EEEKDPDAQKKEEE----RQEALRQQEEERKAKHARMEAEREKVRQQIRDKYGLKKKEEK 78 E+EK + +K++E+ RQE ++EE + +M + EK+R+Q +K ++++ + Sbjct: 462 EQEKIREEEKRQEQEEMWRQEEKIHEQEEIWRQKEKMHEQEEKIRKQ-EEKVWRQEEKIR 520 Query: 79 EAEEK 83 E EEK Sbjct: 521 EQEEK 525 Score = 33.1 bits (74), Expect = 0.069 Identities = 29/104 (27%), Positives = 54/104 (51%), Gaps = 13/104 (12%) Query: 23 EEEKDPDAQKKEEERQEALRQQEE---ERKAKHARMEA----EREKVRQQ---IRDKYGL 72 +EEK + ++K E++E +R+QEE E++ K R E + EK+R+Q + +K Sbjct: 319 QEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEK 378 Query: 73 KKKEEKEAEEKAALEQPCEGSLTRPKKAIPAGCGDEEEEEEESI 116 +++E+ EK + E + +K +E+ +EEE I Sbjct: 379 MRRQEEMMWEKEEKIRELEEKMHEQEKIREQ---EEKRQEEEKI 419 Score = 32.3 bits (72), Expect = 0.12 Identities = 17/66 (25%), Positives = 41/66 (62%), Gaps = 2/66 (3%) Query: 23 EEEKDPDAQKKEEERQEALRQQEEERKAKHARMEAEREKVRQQIRDKYGLKKKEEKEAEE 82 +EEK ++K +E +E +++QEE+ + + ++ + EK+R+Q ++ +K+E+ +E Sbjct: 298 QEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQ--EEMMWEKEEKMRRQE 355 Query: 83 KAALEQ 88 + E+ Sbjct: 356 EMMWEK 361 Score = 32.0 bits (71), Expect = 0.15 Identities = 19/65 (29%), Positives = 37/65 (56%), Gaps = 6/65 (9%) Query: 23 EEEKDPDAQKKEEERQEALRQQ----EEERKAKHARMEAEREKVRQQIRDKYGLKKKEEK 78 +EEK + +KK ++E + +Q EEE++ + M + EK+ +Q ++ +K++ Sbjct: 442 QEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIHEQ--EEIWRQKEKMH 499 Query: 79 EAEEK 83 E EEK Sbjct: 500 EQEEK 504 Score = 31.2 bits (69), Expect = 0.26 Identities = 24/94 (25%), Positives = 50/94 (53%), Gaps = 4/94 (4%) Query: 23 EEEKDPDAQKKEEERQEALRQQEEERKAKHARMEAE--REKVRQQIRDKYGLKKKEEKEA 80 +EE + ++K E +E + +QE+ R+ + R E E RE+ ++Q ++ +++E+ Sbjct: 382 QEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIRE 441 Query: 81 EEKAALEQPCEGSLTRPKKAIPAGCGDEEEEEEE 114 +E+ EQ E + R ++ I EEE+ + Sbjct: 442 QEEKIREQ--EKKMWRQEEKIHEQEKIREEEKRQ 473 Score = 30.8 bits (68), Expect = 0.34 Identities = 21/78 (26%), Positives = 38/78 (48%), Gaps = 17/78 (21%) Query: 23 EEEKDPDAQKKEEERQEALRQQEE-----------------ERKAKHARMEAEREKVRQQ 65 +EEK ++K E++E +R+QEE E + H + + E+ RQ+ Sbjct: 508 QEEKVWRQEEKIREQEEKIREQEEKMWRQEEKIREQEEMWREEEKMHEQEKIWEEEKRQE 567 Query: 66 IRDKYGLKKKEEKEAEEK 83 DK ++++ +E EEK Sbjct: 568 QEDKMWRQEEKIREQEEK 585 Score = 30.8 bits (68), Expect = 0.34 Identities = 23/94 (24%), Positives = 51/94 (54%), Gaps = 6/94 (6%) Query: 23 EEEKDPDAQKKEEERQEALRQ--QEEERKAKHARMEAEREKVRQQIRDKYGLKKKEEKEA 80 E+ ++ + +EEE+ + +EE+R+ + +M + EK+R+Q +K ++++ +E Sbjct: 538 EKIREQEEMWREEEKMHEQEKIWEEEKRQEQEDKMWRQEEKIREQ-EEKVWRQEEKIREQ 596 Query: 81 EEKAALEQPCEGSLTRPKKAIPAGCGDEEEEEEE 114 EEK Q E + + ++ I +E+EE+ Sbjct: 597 EEK---RQEQEEKMWKQEEKIREQEEKIQEQEEK 627 Score = 30.4 bits (67), Expect = 0.44 Identities = 23/78 (29%), Positives = 37/78 (47%), Gaps = 1/78 (1%) Query: 6 KQALGGATKDMGKMLGGEEEKDPDAQKKEEERQEALRQQEEERKAKHARMEAEREKVRQQ 65 +Q L +GK L K AQ +E E L QQ+EE+ + E E+ Q+ Sbjct: 260 QQQLQAEADHLGKELQSVSAK-LQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQE 318 Query: 66 IRDKYGLKKKEEKEAEEK 83 +K ++++ +E EEK Sbjct: 319 QEEKIREQEEKIREQEEK 336 Score = 28.5 bits (62), Expect = 1.7 Identities = 17/71 (23%), Positives = 37/71 (52%) Query: 18 KMLGGEEEKDPDAQKKEEERQEALRQQEEERKAKHARMEAEREKVRQQIRDKYGLKKKEE 77 KM EE+ +K E+ ++ RQ+E+ + + R E +R++ + R + + ++EE Sbjct: 431 KMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIHEQEE 490 Query: 78 KEAEEKAALEQ 88 +++ EQ Sbjct: 491 IWRQKEKMHEQ 501 >gi|115298682 HBxAg transactivated protein 2 [Homo sapiens] Length = 2817 Score = 43.1 bits (100), Expect = 7e-05 Identities = 32/114 (28%), Positives = 59/114 (51%), Gaps = 1/114 (0%) Query: 1 MDFVMKQALGGATKDMGKMLGGEEEKDPDAQKKEEERQEALRQQEEERKAKHARMEAERE 60 M+ K A K + + LG E++ + +E ER++ +++E K + E ERE Sbjct: 473 MEEQRKAACAEKLKRLDEKLGILEKQPSPEEIREREREKEREREKELEKEQEQEREKERE 532 Query: 61 KVRQQIRDK-YGLKKKEEKEAEEKAALEQPCEGSLTRPKKAIPAGCGDEEEEEE 113 K R++ ++K L+K++EK+ E + +Q E L R K+ +E+E+E Sbjct: 533 KDRERQQEKEKELEKEQEKQREMEKERKQEKEKELERQKEKEKELQKMKEQEKE 586 Score = 42.7 bits (99), Expect = 9e-05 Identities = 25/84 (29%), Positives = 47/84 (55%), Gaps = 8/84 (9%) Query: 23 EEEKDPDAQKKEEERQEALRQQEEERKA-KHARMEAEREKVRQQIRDKYGLKKKE----- 76 E E++ + +K++E+ +E R+++ ER+ K +E E+EK R+ +++ K+KE Sbjct: 512 EREREKELEKEQEQEREKEREKDRERQQEKEKELEKEQEKQREMEKERKQEKEKELERQK 571 Query: 77 --EKEAEEKAALEQPCEGSLTRPK 98 EKE ++ E+ CE R K Sbjct: 572 EKEKELQKMKEQEKECELEKEREK 595 Score = 42.7 bits (99), Expect = 9e-05 Identities = 29/101 (28%), Positives = 59/101 (58%), Gaps = 7/101 (6%) Query: 23 EEEKDPDAQKKEEERQEALRQQEEERK-AKHARMEAEREKVRQQIRDKYGLKKKEEKEAE 81 E EK+ + ++++E ++ RQQE+E++ K + E EK R+Q ++K L++++EKE E Sbjct: 518 ELEKEQEQEREKEREKDRERQQEKEKELEKEQEKQREMEKERKQEKEK-ELERQKEKEKE 576 Query: 82 EKAALEQPCEGSLTRPKKAIPAGCGDEEEEEEESILDTVLK 122 + EQ E L + ++ + +E+ E E L+ +++ Sbjct: 577 LQKMKEQEKECELEKEREKL-----EEKIEPREPNLEPMVE 612 Score = 42.7 bits (99), Expect = 9e-05 Identities = 33/98 (33%), Positives = 56/98 (57%), Gaps = 10/98 (10%) Query: 23 EEEKDPDAQKKEEERQEALRQQEEERK-AKHARMEAEREKVRQQIRDKYGLKKKE-EKEA 80 E+E++ D ++++E+ +E ++QE++R+ K + E E+E RQ+ ++K K KE EKE Sbjct: 528 EKEREKDRERQQEKEKELEKEQEKQREMEKERKQEKEKELERQKEKEKELQKMKEQEKEC 587 Query: 81 E---EKAALE---QPCEGSLTR--PKKAIPAGCGDEEE 110 E E+ LE +P E +L K+ C EEE Sbjct: 588 ELEKEREKLEEKIEPREPNLEPMVEKQESENSCNKEEE 625 Score = 38.9 bits (89), Expect = 0.001 Identities = 25/94 (26%), Positives = 48/94 (51%), Gaps = 3/94 (3%) Query: 23 EEEKDPDAQKKEEERQEALRQQEEER---KAKHARMEAEREKVRQQIRDKYGLKKKEEKE 79 EE ++ + +K+ E +E ++QE+ER + K + E+EK ++ ++K +KE K+ Sbjct: 502 EEIREREREKEREREKELEKEQEQEREKEREKDRERQQEKEKELEKEQEKQREMEKERKQ 561 Query: 80 AEEKAALEQPCEGSLTRPKKAIPAGCGDEEEEEE 113 +EK Q + + K C E+E E+ Sbjct: 562 EKEKELERQKEKEKELQKMKEQEKECELEKEREK 595 Score = 36.2 bits (82), Expect = 0.008 Identities = 21/72 (29%), Positives = 42/72 (58%), Gaps = 6/72 (8%) Query: 14 KDMGKMLGGEEEKDPDAQKKEEERQEALRQQEEERKAKHARMEAEREKVRQQIRDKY-GL 72 ++M K E+EK+ + QK++E+ + +++QE+E +E EREK+ ++I + L Sbjct: 553 REMEKERKQEKEKELERQKEKEKELQKMKEQEKE-----CELEKEREKLEEKIEPREPNL 607 Query: 73 KKKEEKEAEEKA 84 + EK+ E + Sbjct: 608 EPMVEKQESENS 619 Score = 35.4 bits (80), Expect = 0.014 Identities = 22/78 (28%), Positives = 42/78 (53%), Gaps = 5/78 (6%) Query: 18 KMLGGEEEKDPDAQK-KEEERQEALRQQEEE----RKAKHARMEAEREKVRQQIRDKYGL 72 K L E+EK + +K +++E+++ L +Q+E+ +K K E E EK R+++ +K Sbjct: 543 KELEKEQEKQREMEKERKQEKEKELERQKEKEKELQKMKEQEKECELEKEREKLEEKIEP 602 Query: 73 KKKEEKEAEEKAALEQPC 90 ++ + EK E C Sbjct: 603 REPNLEPMVEKQESENSC 620 Score = 29.3 bits (64), Expect = 0.99 Identities = 27/113 (23%), Positives = 52/113 (46%), Gaps = 28/113 (24%) Query: 23 EEEKDPDAQKKEEERQEA----------LRQQEEERKAKHARMEAEREKVRQQIRDKYGL 72 ++ D D K+ RQ++ R++EEER+ + R A EK+++ + +K G+ Sbjct: 436 QQVADEDEIWKQRRRQQSEISAAVERARKRREEEERRMEEQRKAACAEKLKR-LDEKLGI 494 Query: 73 KKKE-----------EKEAEEKAALEQPCEGSLTRPKKAIPAGCGDEEEEEEE 114 +K+ EKE E + LE+ E + ++ D E ++E+ Sbjct: 495 LEKQPSPEEIREREREKEREREKELEKEQEQEREKEREK------DRERQQEK 541 >gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo sapiens] Length = 668 Score = 42.4 bits (98), Expect = 1e-04 Identities = 26/101 (25%), Positives = 60/101 (59%), Gaps = 8/101 (7%) Query: 14 KDMGKMLGGEEEKDPDAQKKEEERQEALRQQEEERKAKHARMEAEREKVRQQIRDKYGLK 73 ++ +M+ +EEK + ++K +E QE +R+QEE+ + + ++ ++EK+R+Q + + Sbjct: 540 REQEEMMQEQEEKMGEQEEKMQE-QEKMRRQEEKIREQEEKIREQKEKIREQ---EEKIW 595 Query: 74 KKEEKEAEEKAALEQPCEGSLTRPKKAIPAGCGDEEEEEEE 114 ++EEK E++ +++ E + +K C EE+ +E+ Sbjct: 596 EQEEKIREQEEMMQEQEEKMWEQEEKM----CEQEEKMQEQ 632 Score = 40.4 bits (93), Expect = 4e-04 Identities = 25/94 (26%), Positives = 53/94 (56%), Gaps = 3/94 (3%) Query: 23 EEEKDPDAQKKEEERQEALRQQEEERKAKHARMEAEREKVRQQ---IRDKYGLKKKEEKE 79 +EEK + ++K E++E +R+QEE + + +M + EK+++Q R + ++++EEK Sbjct: 521 QEEKIREQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMQEQEKMRRQEEKIREQEEKI 580 Query: 80 AEEKAALEQPCEGSLTRPKKAIPAGCGDEEEEEE 113 E+K + + E + +K +E+EE+ Sbjct: 581 REQKEKIREQEEKIWEQEEKIREQEEMMQEQEEK 614 Score = 38.9 bits (89), Expect = 0.001 Identities = 25/95 (26%), Positives = 53/95 (55%), Gaps = 9/95 (9%) Query: 24 EEKDPDAQKKEEERQEALRQQEEERKAKHARMEAEREKVRQQ----IRDKYGLKKKEEKE 79 E+++ QK++ QE +R+QEE+ + +M + EK+R+Q R + ++++EEK Sbjct: 473 EQEEIWRQKEKMHEQEKIRKQEEKVWRQEEKMHDQEEKIREQEEKMWRQEEKIREQEEKI 532 Query: 80 AEEKAALEQPCEGSLTRPKKAIPAGCGDEEEEEEE 114 E++ + + E + +K G++EE+ +E Sbjct: 533 REQEEKIREQEEMMQEQEEK-----MGEQEEKMQE 562 Score = 38.9 bits (89), Expect = 0.001 Identities = 18/66 (27%), Positives = 43/66 (65%), Gaps = 3/66 (4%) Query: 23 EEEKDPDAQKKEEERQEALRQQEEERKAKHARMEAEREKVRQQIRDKYGLKKKEEKEAEE 82 +EEK D ++K E++E + +QEE+ + + ++ + EK+R+Q + ++++EEK E+ Sbjct: 500 QEEKMHDQEEKIREQEEKMWRQEEKIREQEEKIREQEEKIREQ---EEMMQEQEEKMGEQ 556 Query: 83 KAALEQ 88 + +++ Sbjct: 557 EEKMQE 562 Score = 38.5 bits (88), Expect = 0.002 Identities = 20/80 (25%), Positives = 48/80 (60%), Gaps = 3/80 (3%) Query: 15 DMGKMLGGEEEKDPDAQKKEEERQEALRQQEEERKAKHARMEAEREKVRQQ---IRDKYG 71 D + + +EEK ++K E++E +R+QEE+ + + M+ + EK+ +Q ++++ Sbjct: 506 DQEEKIREQEEKMWRQEEKIREQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMQEQEK 565 Query: 72 LKKKEEKEAEEKAALEQPCE 91 ++++EEK E++ + + E Sbjct: 566 MRRQEEKIREQEEKIREQKE 585 Score = 38.1 bits (87), Expect = 0.002 Identities = 22/74 (29%), Positives = 45/74 (60%), Gaps = 8/74 (10%) Query: 23 EEEKDPDAQKKEEE------RQEALRQQEEERKAKHARMEAEREKVRQQ--IRDKYGLKK 74 EEEK + +K++E+ ++E +R+QEE+ + + +M + EK+ +Q IR++ ++ Sbjct: 401 EEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQE 460 Query: 75 KEEKEAEEKAALEQ 88 +EE +E+ EQ Sbjct: 461 QEEMWRQEEKIREQ 474 Score = 36.6 bits (83), Expect = 0.006 Identities = 20/69 (28%), Positives = 41/69 (59%), Gaps = 4/69 (5%) Query: 23 EEEKDPDAQKKEEERQEALRQQEEERKAKHARMEAEREKVRQQ----IRDKYGLKKKEEK 78 +EEK + ++ +E++E + +QEE+ + +M+ + EK+R+Q + L+++EEK Sbjct: 597 QEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQEEK 656 Query: 79 EAEEKAALE 87 E + LE Sbjct: 657 MQEHQEHLE 665 Score = 35.8 bits (81), Expect = 0.011 Identities = 26/96 (27%), Positives = 50/96 (52%), Gaps = 6/96 (6%) Query: 24 EEKDPDAQKKEEERQEALRQQEEERKAKHARMEAEREKVRQQ---IRDKYGLKKKEEKEA 80 EEK + ++K E++E +R+QEE+ + + M + EK+R+Q + +K ++ E+ Sbjct: 313 EEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRLEEMM 372 Query: 81 EEKAALEQPCEGSLTRPKKAIPAGCGDEEEEEEESI 116 EK + E + +K +E+ +EEE I Sbjct: 373 WEKEEKIRELEEKMHEQEKIREQ---EEKRQEEEKI 405 Score = 34.7 bits (78), Expect = 0.024 Identities = 21/67 (31%), Positives = 41/67 (61%), Gaps = 6/67 (8%) Query: 23 EEEKDPDAQKKEEERQEALRQQEE---ERKAKHARMEA---EREKVRQQIRDKYGLKKKE 76 +EEK + ++K E++E +R+QEE E++ K R E E+E+ +++ + K+++ Sbjct: 319 QEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRLEEMMWEKEEK 378 Query: 77 EKEAEEK 83 +E EEK Sbjct: 379 IRELEEK 385 Score = 34.7 bits (78), Expect = 0.024 Identities = 23/76 (30%), Positives = 45/76 (59%), Gaps = 10/76 (13%) Query: 23 EEEKDPDAQKKEEERQEALRQQEE---ERKAKHARME----AEREKVR---QQIRDKYGL 72 +EEK ++ E++E +R+QEE E++ K R+E + EK+R +++ ++ + Sbjct: 333 QEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRLEEMMWEKEEKIRELEEKMHEQEKI 392 Query: 73 KKKEEKEAEEKAALEQ 88 +++EEK EE+ EQ Sbjct: 393 REQEEKRQEEEKIREQ 408 Score = 34.7 bits (78), Expect = 0.024 Identities = 17/66 (25%), Positives = 40/66 (60%), Gaps = 3/66 (4%) Query: 23 EEEKDPDAQKKEEERQEALRQQEEERKAKHARMEAEREKVRQQIRDKYGLKKKEEKEAEE 82 E+EK ++K ++E + QEE+ + + +M + EK+R+Q + ++++EEK E+ Sbjct: 486 EQEKIRKQEEKVWRQEEKMHDQEEKIREQEEKMWRQEEKIREQ---EEKIREQEEKIREQ 542 Query: 83 KAALEQ 88 + +++ Sbjct: 543 EEMMQE 548 Score = 34.3 bits (77), Expect = 0.031 Identities = 28/97 (28%), Positives = 51/97 (52%), Gaps = 15/97 (15%) Query: 25 EKDPDAQKKEE---ERQEALRQQEEERKAKHARMEAEREKVRQQ--IRDKYGLKKKEEKE 79 EK+ +++EE E++E +R+ EE K ++ EK+ +Q IR++ +++EEK Sbjct: 346 EKEEKMRRQEEMMWEKEEKMRRLEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKI 405 Query: 80 AEEKAALEQPCEGSLTRPKKAIPAGCGDEEEEEEESI 116 E++ EQ E + R ++ I E+EE I Sbjct: 406 REQEKRQEQ--EAKMWRQEEKI--------REQEEKI 432 Score = 33.9 bits (76), Expect = 0.040 Identities = 22/66 (33%), Positives = 40/66 (60%), Gaps = 4/66 (6%) Query: 18 KMLGGEEEKDPDAQKKEEERQEALRQQEEERKAKHARMEAEREKVRQQIRDKYGLKKKEE 77 +M+ +EEK + ++K E QE +R+QEE+R+ + E E+ RQ+ K ++++ Sbjct: 370 EMMWEKEEKIRELEEKMHE-QEKIREQEEKRQEEEKIREQEK---RQEQEAKMWRQEEKI 425 Query: 78 KEAEEK 83 +E EEK Sbjct: 426 REQEEK 431 Score = 33.9 bits (76), Expect = 0.040 Identities = 21/61 (34%), Positives = 40/61 (65%), Gaps = 3/61 (4%) Query: 23 EEEKDPDAQKKEEERQEALRQQEEERKAKHARMEAEREKVRQQIRDKYGLKKKEEKEAEE 82 E+EK + ++K +E +E +R+QE+ R+ + A+M + EK+R+Q +K ++K+ EE Sbjct: 388 EQEKIREQEEKRQE-EEKIREQEK-RQEQEAKMWRQEEKIREQ-EEKIREQEKKMWRQEE 444 Query: 83 K 83 K Sbjct: 445 K 445 Score = 33.9 bits (76), Expect = 0.040 Identities = 18/61 (29%), Positives = 39/61 (63%), Gaps = 1/61 (1%) Query: 23 EEEKDPDAQKKEEERQEALRQQEEERKAKHARMEAEREKVRQQIRDKYGLKKKEEKEAEE 82 +EEK + ++K E++E + +QEE+ + + M+ + EK+ +Q +K ++++ +E EE Sbjct: 576 QEEKIREQKEKIREQEEKIWEQEEKIREQEEMMQEQEEKMWEQ-EEKMCEQEEKMQEQEE 634 Query: 83 K 83 K Sbjct: 635 K 635 Score = 33.9 bits (76), Expect = 0.040 Identities = 19/70 (27%), Positives = 41/70 (58%), Gaps = 4/70 (5%) Query: 23 EEEKDPDAQKKEEERQEALRQQEEERKAKHARMEAEREKVRQQ----IRDKYGLKKKEEK 78 ++EK + ++K E++E +R+QEE + + +M + EK+ +Q + ++++EEK Sbjct: 583 QKEKIREQEEKIWEQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEK 642 Query: 79 EAEEKAALEQ 88 E++ L Q Sbjct: 643 MWEQEVRLRQ 652 Score = 33.1 bits (74), Expect = 0.069 Identities = 21/77 (27%), Positives = 44/77 (57%), Gaps = 6/77 (7%) Query: 18 KMLGGEEEKDPDAQKKEEER---QEALRQQEEERKAKHARMEAEREKVRQQIRDKYGLKK 74 KM E+ ++ + +++EEE+ QE ++QE + + ++ + EK+R+Q + + ++ Sbjct: 385 KMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEE 444 Query: 75 K---EEKEAEEKAALEQ 88 K +EK EE+ EQ Sbjct: 445 KIHEQEKIREEEKRQEQ 461 Score = 33.1 bits (74), Expect = 0.069 Identities = 16/66 (24%), Positives = 40/66 (60%) Query: 23 EEEKDPDAQKKEEERQEALRQQEEERKAKHARMEAEREKVRQQIRDKYGLKKKEEKEAEE 82 +EEK + +KK ++E + +QE+ R+ + + + E + ++IR++ + +++EK E+ Sbjct: 428 QEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKMHEQ 487 Query: 83 KAALEQ 88 + +Q Sbjct: 488 EKIRKQ 493 Score = 32.3 bits (72), Expect = 0.12 Identities = 17/66 (25%), Positives = 41/66 (62%), Gaps = 2/66 (3%) Query: 23 EEEKDPDAQKKEEERQEALRQQEEERKAKHARMEAEREKVRQQIRDKYGLKKKEEKEAEE 82 +EEK ++K +E +E +++QEE+ + + ++ + EK+R+Q ++ +K+E+ +E Sbjct: 298 QEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQ--EEMMWEKEEKMRRQE 355 Query: 83 KAALEQ 88 + E+ Sbjct: 356 EMMWEK 361 Score = 30.4 bits (67), Expect = 0.44 Identities = 23/78 (29%), Positives = 37/78 (47%), Gaps = 1/78 (1%) Query: 6 KQALGGATKDMGKMLGGEEEKDPDAQKKEEERQEALRQQEEERKAKHARMEAEREKVRQQ 65 +Q L +GK L K AQ +E E L QQ+EE+ + E E+ Q+ Sbjct: 260 QQQLQAEADHLGKELQSVSAK-LQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQE 318 Query: 66 IRDKYGLKKKEEKEAEEK 83 +K ++++ +E EEK Sbjct: 319 QEEKIREQEEKIREQEEK 336 Score = 30.0 bits (66), Expect = 0.58 Identities = 20/73 (27%), Positives = 44/73 (60%), Gaps = 5/73 (6%) Query: 14 KDMGKMLGGEEEKDPDAQK-KEEERQEALRQQEEERKAKHARMEAEREKVRQQIRDKYGL 72 ++ K + +EEK + +K +EEE+++ Q+E R+ + R + E + ++++ ++ + Sbjct: 433 REQEKKMWRQEEKIHEQEKIREEEKRQ--EQEEMWRQEEKIREQEEIWRQKEKMHEQEKI 490 Query: 73 KKKEEK--EAEEK 83 +K+EEK EEK Sbjct: 491 RKQEEKVWRQEEK 503 Score = 30.0 bits (66), Expect = 0.58 Identities = 20/66 (30%), Positives = 40/66 (60%), Gaps = 8/66 (12%) Query: 23 EEEKDPDAQKKEEE-----RQEALRQQEEERKAKHARMEAEREKVRQQIRDKYGLKKKEE 77 E+EK + +K++E+ ++E +R+QEE + K E +EK+R+Q +K ++++ Sbjct: 448 EQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKMHE--QEKIRKQ-EEKVWRQEEKM 504 Query: 78 KEAEEK 83 + EEK Sbjct: 505 HDQEEK 510 Score = 29.6 bits (65), Expect = 0.76 Identities = 17/71 (23%), Positives = 38/71 (53%) Query: 18 KMLGGEEEKDPDAQKKEEERQEALRQQEEERKAKHARMEAEREKVRQQIRDKYGLKKKEE 77 KM EE+ +K E+ ++ RQ+E+ + + R E +R++ + R + ++++EE Sbjct: 417 KMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEE 476 Query: 78 KEAEEKAALEQ 88 +++ EQ Sbjct: 477 IWRQKEKMHEQ 487 Score = 29.3 bits (64), Expect = 0.99 Identities = 17/65 (26%), Positives = 41/65 (63%), Gaps = 4/65 (6%) Query: 18 KMLGGEEEKDPDAQKKEEERQEALRQQEEE-RKAKHARMEAEREKVRQQIRDKYGLKKKE 76 +M+ +EEK ++ E++E +R+ EE+ + + R + E+ + ++IR++ +K++ Sbjct: 356 EMMWEKEEKMRRLEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQ---EKRQ 412 Query: 77 EKEAE 81 E+EA+ Sbjct: 413 EQEAK 417 >gi|195927037 DNA (cytosine-5-)-methyltransferase 1 isoform a [Homo sapiens] Length = 1632 Score = 42.4 bits (98), Expect = 1e-04 Identities = 30/92 (32%), Positives = 43/92 (46%), Gaps = 11/92 (11%) Query: 21 GGEEEKDPDAQKKEEERQEALRQQEEERKAKHARMEAEREKVRQQIRDKYGLKKKEEKE- 79 G + ++D D +K+E++ R Q ++ AK E E EKV QI D+ +KEEK Sbjct: 285 GVQADEDEDGDEKDEKKH---RSQPKDLAAKRRPEEKEPEKVNPQISDEKDEDEKEEKRR 341 Query: 80 -------AEEKAALEQPCEGSLTRPKKAIPAG 104 E+K A + S T P K I G Sbjct: 342 KTTPKEPTEKKMARAKTVMNSKTHPPKCIQCG 373 Score = 34.3 bits (77), Expect = 0.031 Identities = 27/97 (27%), Positives = 43/97 (44%), Gaps = 6/97 (6%) Query: 21 GGEEEKDPDAQKKEEERQEALRQQEEERKAKHARMEAEREKVR---QQIRDKYGLKKKEE 77 G EK+ + +KEE+R LR Q +E K E + R Q D+ G +K E+ Sbjct: 244 GTRTEKEEERDEKEEKR---LRSQTKEPTPKQKLKEEPDREARAGVQADEDEDGDEKDEK 300 Query: 78 KEAEEKAALEQPCEGSLTRPKKAIPAGCGDEEEEEEE 114 K + L P+K P +++E+E+E Sbjct: 301 KHRSQPKDLAAKRRPEEKEPEKVNPQISDEKDEDEKE 337 Score = 31.6 bits (70), Expect = 0.20 Identities = 21/105 (20%), Positives = 52/105 (49%), Gaps = 13/105 (12%) Query: 22 GEEEKDPDAQKKEEERQEALRQQEEERKAKHARMEAEREKVRQQI------RDKYGLKKK 75 G ++ P + + + E+++++++++ K R+ + RE+V + + R K G + + Sbjct: 190 GPAKRKPQEESERAKSDESIKEEDKDQDEKRRRVTS-RERVARPLPAEEPERAKSGTRTE 248 Query: 76 EEKEAEEKAALEQPCEGSLTRPKKAI------PAGCGDEEEEEEE 114 +E+E +EK + PK+ + A G + +E+E+ Sbjct: 249 KEEERDEKEEKRLRSQTKEPTPKQKLKEEPDREARAGVQADEDED 293 >gi|4503351 DNA (cytosine-5-)-methyltransferase 1 isoform b [Homo sapiens] Length = 1616 Score = 42.4 bits (98), Expect = 1e-04 Identities = 30/92 (32%), Positives = 43/92 (46%), Gaps = 11/92 (11%) Query: 21 GGEEEKDPDAQKKEEERQEALRQQEEERKAKHARMEAEREKVRQQIRDKYGLKKKEEKE- 79 G + ++D D +K+E++ R Q ++ AK E E EKV QI D+ +KEEK Sbjct: 269 GVQADEDEDGDEKDEKKH---RSQPKDLAAKRRPEEKEPEKVNPQISDEKDEDEKEEKRR 325 Query: 80 -------AEEKAALEQPCEGSLTRPKKAIPAG 104 E+K A + S T P K I G Sbjct: 326 KTTPKEPTEKKMARAKTVMNSKTHPPKCIQCG 357 Score = 34.3 bits (77), Expect = 0.031 Identities = 27/97 (27%), Positives = 43/97 (44%), Gaps = 6/97 (6%) Query: 21 GGEEEKDPDAQKKEEERQEALRQQEEERKAKHARMEAEREKVR---QQIRDKYGLKKKEE 77 G EK+ + +KEE+R LR Q +E K E + R Q D+ G +K E+ Sbjct: 228 GTRTEKEEERDEKEEKR---LRSQTKEPTPKQKLKEEPDREARAGVQADEDEDGDEKDEK 284 Query: 78 KEAEEKAALEQPCEGSLTRPKKAIPAGCGDEEEEEEE 114 K + L P+K P +++E+E+E Sbjct: 285 KHRSQPKDLAAKRRPEEKEPEKVNPQISDEKDEDEKE 321 Score = 31.6 bits (70), Expect = 0.20 Identities = 21/105 (20%), Positives = 52/105 (49%), Gaps = 13/105 (12%) Query: 22 GEEEKDPDAQKKEEERQEALRQQEEERKAKHARMEAEREKVRQQI------RDKYGLKKK 75 G ++ P + + + E+++++++++ K R+ + RE+V + + R K G + + Sbjct: 174 GPAKRKPQEESERAKSDESIKEEDKDQDEKRRRVTS-RERVARPLPAEEPERAKSGTRTE 232 Query: 76 EEKEAEEKAALEQPCEGSLTRPKKAI------PAGCGDEEEEEEE 114 +E+E +EK + PK+ + A G + +E+E+ Sbjct: 233 KEEERDEKEEKRLRSQTKEPTPKQKLKEEPDREARAGVQADEDED 277 >gi|148806928 hypothetical protein LOC57482 [Homo sapiens] Length = 1233 Score = 42.4 bits (98), Expect = 1e-04 Identities = 32/100 (32%), Positives = 50/100 (50%), Gaps = 15/100 (15%) Query: 29 DAQKKEEERQEALRQQEEERKAK-------------HARMEAEREKVRQQIRDKYGLKKK 75 DA+++E E +E L +EE R+ + AR+E R + ++ R LK++ Sbjct: 302 DAERREREERERLEAEEERRRLQAQAQAEERRRLEEDARLEERRRQEEEEGRCAEELKRQ 361 Query: 76 EEKEAEEKAALEQPCEGSLTRPKKAI-PAGCGDEEEEEEE 114 EE+EAE LEQ E + P +A+ G G EEE+ Sbjct: 362 EEEEAEGWEELEQQ-EAEVQGPPEALEETGEGRRGAEEED 400 Score = 32.0 bits (71), Expect = 0.15 Identities = 28/104 (26%), Positives = 50/104 (48%), Gaps = 25/104 (24%) Query: 22 GEEEKDP----DAQKKEEER-------QEALRQQEEERKAKHARMEAEREKVRQQIRDKY 70 GE ++ P A ++E++R ++A R++ EER+ R+EAE E+ R Q Sbjct: 274 GEGQEPPLEAERAPREEQQRSLEAPGWEDAERREREERE----RLEAEEERRRLQA---- 325 Query: 71 GLKKKEEKEAEEKAALEQPCEGSLTRPKKAIPAGCGDEEEEEEE 114 + +AEE+ LE+ R ++ C +E + +EE Sbjct: 326 ------QAQAEERRRLEEDARLEERRRQEEEEGRCAEELKRQEE 363 Score = 28.9 bits (63), Expect = 1.3 Identities = 23/70 (32%), Positives = 36/70 (51%), Gaps = 2/70 (2%) Query: 23 EEEKDPDAQKKEEERQEALRQQEEERKAKHARMEAEREKVRQQIRDKYGLKKKEEKEAEE 82 EEE +P ++E RQE +E E K K + EA EK R + + L+++ +E Sbjct: 209 EEEPNPLDSEEERRRQEDY-WRELEAKCKRQKAEA-AEKRRLEEQRLQALERRLWEENRR 266 Query: 83 KAALEQPCEG 92 + LE+ EG Sbjct: 267 QELLEEEGEG 276 >gi|155030232 proline, glutamic acid and leucine rich protein 1 [Homo sapiens] Length = 1130 Score = 42.0 bits (97), Expect = 1e-04 Identities = 17/61 (27%), Positives = 38/61 (62%) Query: 23 EEEKDPDAQKKEEERQEALRQQEEERKAKHARMEAEREKVRQQIRDKYGLKKKEEKEAEE 82 EEE++ + +++EEE +E ++EE+ + E E E+ ++ ++ G ++EE+E +E Sbjct: 892 EEEEEEEEEEEEEEEEEDFEEEEEDEEEYFEEEEEEEEEFEEEFEEEEGELEEEEEEEDE 951 Query: 83 K 83 + Sbjct: 952 E 952 Score = 37.7 bits (86), Expect = 0.003 Identities = 19/65 (29%), Positives = 38/65 (58%), Gaps = 3/65 (4%) Query: 23 EEEKDPDAQKKEEERQEALRQQEEERKAKHARMEAEREKVRQQIRDKYGLKKKEEKEAEE 82 EEE++ D +++EE+ +E ++EEE + E E ++ ++ ++ ++EE+E EE Sbjct: 903 EEEEEEDFEEEEEDEEEYFEEEEEEEEEFEEEFEEEEGELEEEEEEE---DEEEEEELEE 959 Query: 83 KAALE 87 LE Sbjct: 960 VEDLE 964 Score = 37.0 bits (84), Expect = 0.005 Identities = 27/92 (29%), Positives = 46/92 (50%), Gaps = 15/92 (16%) Query: 29 DAQKKEEERQEALRQQEEERKAKHARMEAEREKVRQQIRDKYGLKKKEEKEAEEKAALEQ 88 ++ +EEE +E ++EEE + + E E E + + +++EE+E EE+ E Sbjct: 884 NSSDEEEEEEEEEEEEEEEEEEEEEDFEEEEEDEEEYFEE----EEEEEEEFEEEFEEE- 938 Query: 89 PCEGSLTRPKKAIPAGCGDEEEEEEESILDTV 120 EG L + +EE+EEEE L+ V Sbjct: 939 --EGELEEEE--------EEEDEEEEEELEEV 960 Score = 31.2 bits (69), Expect = 0.26 Identities = 19/66 (28%), Positives = 35/66 (53%), Gaps = 7/66 (10%) Query: 23 EEEKDPDAQKKEEERQEALRQQEEERKAKHARMEAEREKVRQQIRDKYGLKKKEEKEAEE 82 EEE++ + +EEE E +EEE + + E E E+ + +++EE++ EE Sbjct: 901 EEEEEEEEDFEEEEEDEEEYFEEEEEEEEEFEEEFEEEEGELE-------EEEEEEDEEE 953 Query: 83 KAALEQ 88 + LE+ Sbjct: 954 EEELEE 959 >gi|18426913 drebrin 1 isoform b [Homo sapiens] Length = 651 Score = 42.0 bits (97), Expect = 1e-04 Identities = 23/86 (26%), Positives = 48/86 (55%), Gaps = 3/86 (3%) Query: 33 KEEERQEALRQQEEERKAKHARMEAEREKV---RQQIRDKYGLKKKEEKEAEEKAALEQP 89 ++ +++E LR++EE +KA R+ E+E++ RQ+ ++ ++ E++ EE +Q Sbjct: 184 EQAKKEEELRKEEERKKALDERLRFEQERMEQERQEQEERERRYREREQQIEEHRRKQQT 243 Query: 90 CEGSLTRPKKAIPAGCGDEEEEEEES 115 E + + + GD +EEEE+ Sbjct: 244 LEAEEAKRRLKEQSIFGDHRDEEEET 269 Score = 37.4 bits (85), Expect = 0.004 Identities = 22/73 (30%), Positives = 40/73 (54%), Gaps = 3/73 (4%) Query: 14 KDMGKMLGGEEEKDPDAQKKEEERQEALRQQE---EERKAKHARMEAEREKVRQQIRDKY 70 K + + L E+E+ ++++EER+ R++E EE + K +EAE K R + + + Sbjct: 200 KALDERLRFEQERMEQERQEQEERERRYREREQQIEEHRRKQQTLEAEEAKRRLKEQSIF 259 Query: 71 GLKKKEEKEAEEK 83 G + EE+E K Sbjct: 260 GDHRDEEEETHMK 272 >gi|18426915 drebrin 1 isoform a [Homo sapiens] Length = 649 Score = 42.0 bits (97), Expect = 1e-04 Identities = 23/86 (26%), Positives = 48/86 (55%), Gaps = 3/86 (3%) Query: 33 KEEERQEALRQQEEERKAKHARMEAEREKV---RQQIRDKYGLKKKEEKEAEEKAALEQP 89 ++ +++E LR++EE +KA R+ E+E++ RQ+ ++ ++ E++ EE +Q Sbjct: 182 EQAKKEEELRKEEERKKALDERLRFEQERMEQERQEQEERERRYREREQQIEEHRRKQQT 241 Query: 90 CEGSLTRPKKAIPAGCGDEEEEEEES 115 E + + + GD +EEEE+ Sbjct: 242 LEAEEAKRRLKEQSIFGDHRDEEEET 267 Score = 37.4 bits (85), Expect = 0.004 Identities = 22/73 (30%), Positives = 40/73 (54%), Gaps = 3/73 (4%) Query: 14 KDMGKMLGGEEEKDPDAQKKEEERQEALRQQE---EERKAKHARMEAEREKVRQQIRDKY 70 K + + L E+E+ ++++EER+ R++E EE + K +EAE K R + + + Sbjct: 198 KALDERLRFEQERMEQERQEQEERERRYREREQQIEEHRRKQQTLEAEEAKRRLKEQSIF 257 Query: 71 GLKKKEEKEAEEK 83 G + EE+E K Sbjct: 258 GDHRDEEEETHMK 270 >gi|239749449 PREDICTED: hypothetical protein [Homo sapiens] Length = 275 Score = 41.6 bits (96), Expect = 2e-04 Identities = 16/64 (25%), Positives = 42/64 (65%) Query: 25 EKDPDAQKKEEERQEALRQQEEERKAKHARMEAEREKVRQQIRDKYGLKKKEEKEAEEKA 84 +++ + +K+ ER++ R++E+ERK + + E ++ K R++ +++ +K+ EK+ +E+ Sbjct: 31 QRESERKKERREREKRKREREKERKRERGKKEKKKRKKRERGKERERKRKEREKQRKERR 90 Query: 85 ALEQ 88 E+ Sbjct: 91 EKER 94 Score = 40.8 bits (94), Expect = 3e-04 Identities = 25/71 (35%), Positives = 39/71 (54%), Gaps = 1/71 (1%) Query: 14 KDMGKMLGGEEEKDPDAQKKEEERQEALRQQEEERKAKHARMEAERE-KVRQQIRDKYGL 72 K+ K EK+ +KKE++++E ++ ERK K R E ERE K R++ + K Sbjct: 80 KEREKQRKERREKERRKRKKEKKKRERKQRGRRERKKKKERKERERENKQRRERKRKKRR 139 Query: 73 KKKEEKEAEEK 83 KKK KE + + Sbjct: 140 KKKRRKERKRE 150 Score = 40.4 bits (93), Expect = 4e-04 Identities = 21/61 (34%), Positives = 38/61 (62%), Gaps = 3/61 (4%) Query: 23 EEEKDPDAQKKEEERQEALRQQEEERKAKHARMEAEREKVRQQIRDKYGLKKKEEKEAEE 82 E EK+ +K+E ++E ++++ ER + R EREK R++ R+K K+K+EK+ E Sbjct: 49 EREKE---RKRERGKKEKKKRKKRERGKERERKRKEREKQRKERREKERRKRKKEKKKRE 105 Query: 83 K 83 + Sbjct: 106 R 106 Score = 39.7 bits (91), Expect = 7e-04 Identities = 23/75 (30%), Positives = 43/75 (57%), Gaps = 2/75 (2%) Query: 14 KDMGKMLGGEEEKDPDAQKKEEERQEALRQQEEERKAKHARMEAEREKVRQQIRDKYGLK 73 K+ K E K+ + ++KE E+Q R+++E RK K + + ER++ ++ R K K Sbjct: 61 KEKKKRKKRERGKERERKRKEREKQRKERREKERRKRKKEKKKRERKQRGRRERKK--KK 118 Query: 74 KKEEKEAEEKAALEQ 88 +++E+E E K E+ Sbjct: 119 ERKERERENKQRRER 133 Score = 38.5 bits (88), Expect = 0.002 Identities = 21/64 (32%), Positives = 36/64 (56%), Gaps = 2/64 (3%) Query: 22 GEEEKDPDAQKKEEERQEALRQQEE--ERKAKHARMEAEREKVRQQIRDKYGLKKKEEKE 79 G E+ ++KE ER+ R++ + +R+ K R E +REK R + K +KKEE+E Sbjct: 110 GRRERKKKKERKERERENKQRRERKRKKRRKKKRRKERKREKERGKRERKRKKRKKEERE 169 Query: 80 AEEK 83 + + Sbjct: 170 KKRE 173 Score = 38.1 bits (87), Expect = 0.002 Identities = 22/79 (27%), Positives = 44/79 (55%), Gaps = 2/79 (2%) Query: 23 EEEKDPDAQKKEEERQEALRQQEEERKAKHARMEAEREKVRQQIRDKYGLKKKEE--KEA 80 E E ++K ++R++ R++E +R+ + + E +R+K +++ R+K + ++E KE Sbjct: 124 ERENKQRRERKRKKRRKKKRRKERKREKERGKRERKRKKRKKEEREKKRERNRKERKKER 183 Query: 81 EEKAALEQPCEGSLTRPKK 99 E K E+ E R KK Sbjct: 184 ERKERRERKKERKKERRKK 202 Score = 37.7 bits (86), Expect = 0.003 Identities = 16/61 (26%), Positives = 38/61 (62%) Query: 23 EEEKDPDAQKKEEERQEALRQQEEERKAKHARMEAEREKVRQQIRDKYGLKKKEEKEAEE 82 +E K + K E +++ +++E E+K + R E ++E+ R++ R++ +KKE ++ +E Sbjct: 145 KERKREKERGKRERKRKKRKKEEREKKRERNRKERKKERERKERRERKKERKKERRKKKE 204 Query: 83 K 83 + Sbjct: 205 R 205 Score = 37.0 bits (84), Expect = 0.005 Identities = 18/57 (31%), Positives = 33/57 (57%) Query: 22 GEEEKDPDAQKKEEERQEALRQQEEERKAKHARMEAEREKVRQQIRDKYGLKKKEEK 78 G+ E+ +KKEE ++ R ++E +K + + ER+K R++ R K +KK+ K Sbjct: 154 GKRERKRKKRKKEEREKKRERNRKERKKERERKERRERKKERKKERRKKKERKKDRK 210 Score = 34.7 bits (78), Expect = 0.024 Identities = 23/91 (25%), Positives = 46/91 (50%), Gaps = 5/91 (5%) Query: 14 KDMGKMLGGEEEKDPDAQKKEEERQEALRQQEEERKAKHARMEAEREK-----VRQQIRD 68 K+ + G +E+K +++ +ER+ +++E++RK + + +R+K R+Q Sbjct: 52 KERKRERGKKEKKKRKKRERGKERERKRKEREKQRKERREKERRKRKKEKKKRERKQRGR 111 Query: 69 KYGLKKKEEKEAEEKAALEQPCEGSLTRPKK 99 + KKKE KE E + + + R KK Sbjct: 112 RERKKKKERKERERENKQRRERKRKKRRKKK 142 Score = 32.7 bits (73), Expect = 0.089 Identities = 20/61 (32%), Positives = 35/61 (57%), Gaps = 1/61 (1%) Query: 23 EEEKDPDAQKKEEERQEALRQQEEERKAKHARMEAEREKVRQQIRDKYGLKKKEEKEAEE 82 E++K Q+ ER++ ++E ER+ K R E +R+K R++ R K ++KE + E Sbjct: 100 EKKKRERKQRGRRERKKKKERKERERENKQ-RRERKRKKRRKKKRRKERKREKERGKRER 158 Query: 83 K 83 K Sbjct: 159 K 159 Score = 29.6 bits (65), Expect = 0.76 Identities = 18/45 (40%), Positives = 30/45 (66%), Gaps = 2/45 (4%) Query: 23 EEEKDPDAQKKEEERQEALRQQEEERKAKHARMEAEREKVRQQIR 67 + E++ +KKE ER+E R++++ERK K R + ER+K R+ R Sbjct: 171 KRERNRKERKKERERKER-RERKKERK-KERRKKKERKKDRKTDR 213 >gi|40254924 leucine rich repeat containing 59 [Homo sapiens] Length = 307 Score = 41.6 bits (96), Expect = 2e-04 Identities = 28/104 (26%), Positives = 56/104 (53%), Gaps = 7/104 (6%) Query: 6 KQALGGATKDMGKMLGGEEEKDPDAQKKEEERQEALRQQEEERKAKHA-------RMEAE 58 KQ A K + M + +++ + Q++ E +EA +++E +++AK A R +AE Sbjct: 135 KQCKQCANKVLQHMKAVQADQERERQRRLEVEREAEKKREAKQRAKEAQERELRKREKAE 194 Query: 59 REKVRQQIRDKYGLKKKEEKEAEEKAALEQPCEGSLTRPKKAIP 102 ++ R++ D K+E+++ +K A + P S +RP+K P Sbjct: 195 EKERRRKEYDALKAAKREQEKKPKKEANQAPKSKSGSRPRKPPP 238 >gi|190684694 ubiquitin specific peptidase 8 [Homo sapiens] Length = 1118 Score = 41.6 bits (96), Expect = 2e-04 Identities = 18/53 (33%), Positives = 38/53 (71%) Query: 31 QKKEEERQEALRQQEEERKAKHARMEAEREKVRQQIRDKYGLKKKEEKEAEEK 83 ++++EE++E LR++E+E+KAK + E E +Q + K ++KKE ++A+++ Sbjct: 484 ERQQEEQKEKLRKEEQEQKAKKKQEAEENEITEKQQKAKEEMEKKESEQAKKE 536 Score = 33.5 bits (75), Expect = 0.052 Identities = 17/65 (26%), Positives = 36/65 (55%), Gaps = 3/65 (4%) Query: 23 EEEKDPDAQKKEEERQEALRQQEEERKAKHARMEAEREKVRQQIRDKYGLKKKEEKEAEE 82 ++E+ + +KEE+ Q+A ++QE E + + +E++ ++ ++ KKE+KE Sbjct: 486 QQEEQKEKLRKEEQEQKAKKKQEAEENEITEKQQKAKEEMEKKESEQ---AKKEDKETSA 542 Query: 83 KAALE 87 K E Sbjct: 543 KRGKE 547 Score = 32.0 bits (71), Expect = 0.15 Identities = 14/51 (27%), Positives = 32/51 (62%) Query: 32 KKEEERQEALRQQEEERKAKHARMEAEREKVRQQIRDKYGLKKKEEKEAEE 82 +K ++ +E +Q+EE+K K + E E++ ++Q ++ + +K++K EE Sbjct: 474 EKNKQEKELRERQQEEQKEKLRKEEQEQKAKKKQEAEENEITEKQQKAKEE 524 Score = 30.8 bits (68), Expect = 0.34 Identities = 17/70 (24%), Positives = 43/70 (61%), Gaps = 8/70 (11%) Query: 23 EEEKDPDAQKKEE-------ERQEALRQQEEERKAKHARMEAEREKVRQQIRDKYGLKKK 75 +EE++ A+KK+E E+Q+ +++ E+++++ A+ E ++E ++ ++ G+K++ Sbjct: 496 KEEQEQKAKKKQEAEENEITEKQQKAKEEMEKKESEQAKKE-DKETSAKRGKEITGVKRQ 554 Query: 76 EEKEAEEKAA 85 + E E A Sbjct: 555 SKSEHETSDA 564 Score = 30.0 bits (66), Expect = 0.58 Identities = 16/73 (21%), Positives = 39/73 (53%), Gaps = 3/73 (4%) Query: 27 DPDAQKKEEERQEALRQQEEERKAKHARMEAEREKVRQQIRDKYGLKKKEEKEAEEKAAL 86 D + + E + + ++E++ + + E ++EK+R++ +++ K K+++EAEE Sbjct: 459 DEEKARIHAETALLMEKNKQEKELRERQQEEQKEKLRKEEQEQ---KAKKKQEAEENEIT 515 Query: 87 EQPCEGSLTRPKK 99 E+ + KK Sbjct: 516 EKQQKAKEEMEKK 528 Score = 28.1 bits (61), Expect = 2.2 Identities = 25/93 (26%), Positives = 44/93 (47%), Gaps = 9/93 (9%) Query: 28 PDAQKKEEERQEALRQQEEERKAKHAR--MEAEREKVRQQIRDKYGLKKKE---EKEAEE 82 PD K L +EE+ HA + E+ K +++R++ ++KE ++E E+ Sbjct: 442 PDRSTKPVVFSPTLMLTDEEKARIHAETALLMEKNKQEKELRERQQEEQKEKLRKEEQEQ 501 Query: 83 KAALEQPCEGSLTRPKKAIPAGCGDEEEEEEES 115 KA +Q E + K+ EE E++ES Sbjct: 502 KAKKKQEAEENEITEKQQ----KAKEEMEKKES 530 Score = 26.2 bits (56), Expect = 8.4 Identities = 15/66 (22%), Positives = 33/66 (50%), Gaps = 2/66 (3%) Query: 24 EEKDPDAQKKEEERQEALRQQEEERKAKHARMEAEREKVRQQIRDKYGLKKKEEKEAEEK 83 E+K+ + KKE++ A R +E + ++ E E ++ + D+ K+ E ++K Sbjct: 526 EKKESEQAKKEDKETSAKRGKEITGVKRQSKSEHETSDAKKSVEDRG--KRCPTPEIQKK 583 Query: 84 AALEQP 89 + + P Sbjct: 584 STGDVP 589 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.305 0.127 0.339 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 6,067,777 Number of Sequences: 37866 Number of extensions: 344086 Number of successful extensions: 14960 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 857 Number of HSP's successfully gapped in prelim test: 691 Number of HSP's that attempted gapping in prelim test: 3425 Number of HSP's gapped (non-prelim): 7043 length of query: 134 length of database: 18,247,518 effective HSP length: 91 effective length of query: 43 effective length of database: 14,801,712 effective search space: 636473616 effective search space used: 636473616 T: 11 A: 40 X1: 16 ( 7.0 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 43 (21.9 bits) S2: 56 (26.2 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.