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Search of human proteins with 56549131
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|56549131 transmembrane anchor protein 1 isoform 1 [Homo
sapiens]
(204 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|56549131 transmembrane anchor protein 1 isoform 1 [Homo sapiens] 412 e-115
gi|56549133 transmembrane anchor protein 1 isoform 2 [Homo sapiens] 342 1e-94
gi|56549129 transmembrane anchor protein 1 isoform 3 [Homo sapiens] 341 2e-94
gi|155030232 proline, glutamic acid and leucine rich protein 1 [... 55 3e-08
gi|110832843 TBP-associated factor 4 [Homo sapiens] 55 4e-08
gi|111118994 brain-specific angiogenesis inhibitor 1 precursor [... 53 2e-07
gi|217416350 cask-interacting protein 2 isoform b [Homo sapiens] 53 2e-07
gi|217416347 cask-interacting protein 2 isoform a [Homo sapiens] 53 2e-07
gi|32455273 WNK lysine deficient protein kinase 2 [Homo sapiens] 53 2e-07
gi|78190492 retinitis pigmentosa GTPase regulator isoform C [Hom... 52 3e-07
gi|78042577 MAP7 domain containing 1 [Homo sapiens] 52 3e-07
gi|156071470 hyperpolarization activated cyclic nucleotide-gated... 52 5e-07
gi|111118976 collagen, type II, alpha 1 isoform 1 precursor [Hom... 51 6e-07
gi|111118974 collagen, type II, alpha 1 isoform 2 precursor [Hom... 51 6e-07
gi|32307177 forkhead box G1 [Homo sapiens] 51 6e-07
gi|24308115 interferon regulatory factor 2 binding protein 1 [Ho... 51 8e-07
gi|116256445 nuclear receptor co-repressor 2 isoform 2 [Homo sap... 50 1e-06
gi|116256453 nuclear receptor co-repressor 2 isoform 1 [Homo sap... 50 1e-06
gi|153070260 myristoylated alanine-rich protein kinase C substra... 50 1e-06
gi|111118972 collagen, type XI, alpha 2 isoform 2 preproprotein ... 50 2e-06
gi|111118968 collagen, type XI, alpha 2 isoform 3 preproprotein ... 50 2e-06
gi|111118970 collagen, type XI, alpha 2 isoform 1 preproprotein ... 50 2e-06
gi|194578898 hypothetical protein LOC100170841 [Homo sapiens] 49 2e-06
gi|85815829 SH3-domain binding protein 1 [Homo sapiens] 49 2e-06
gi|169790903 cyclin-dependent kinase inhibitor 1C isoform b [Hom... 49 3e-06
gi|169790899 cyclin-dependent kinase inhibitor 1C isoform b [Hom... 49 3e-06
gi|4557441 cyclin-dependent kinase inhibitor 1C isoform a [Homo ... 49 3e-06
gi|89276751 alpha 1 type V collagen preproprotein [Homo sapiens] 49 3e-06
gi|157168329 formin 1 [Homo sapiens] 49 4e-06
gi|237757312 synaptojanin 1 isoform c [Homo sapiens] 48 5e-06
>gi|56549131 transmembrane anchor protein 1 isoform 1 [Homo sapiens]
Length = 204
Score = 412 bits (1058), Expect = e-115
Identities = 204/204 (100%), Positives = 204/204 (100%)
Query: 1 MEAPAELLAALPALATALALLLAWLLVRRGAAASPEPARAPPEPAPPAEATGAPAPSRPC 60
MEAPAELLAALPALATALALLLAWLLVRRGAAASPEPARAPPEPAPPAEATGAPAPSRPC
Sbjct: 1 MEAPAELLAALPALATALALLLAWLLVRRGAAASPEPARAPPEPAPPAEATGAPAPSRPC 60
Query: 61 APEPAASPAGPEEPGEPAGLGELGEPAGPGEPEGPGDPAAAPAEAEEQAVEARQEEEQDL 120
APEPAASPAGPEEPGEPAGLGELGEPAGPGEPEGPGDPAAAPAEAEEQAVEARQEEEQDL
Sbjct: 61 APEPAASPAGPEEPGEPAGLGELGEPAGPGEPEGPGDPAAAPAEAEEQAVEARQEEEQDL 120
Query: 121 DGEKGPSSEGPEEEDGEGFSFKYSPGKLRGNQYKKMMTKEELEEEQRVQKEQLAAIFKLM 180
DGEKGPSSEGPEEEDGEGFSFKYSPGKLRGNQYKKMMTKEELEEEQRVQKEQLAAIFKLM
Sbjct: 121 DGEKGPSSEGPEEEDGEGFSFKYSPGKLRGNQYKKMMTKEELEEEQRVQKEQLAAIFKLM 180
Query: 181 KDNKETFGEMSDGDVQEQLRLYDM 204
KDNKETFGEMSDGDVQEQLRLYDM
Sbjct: 181 KDNKETFGEMSDGDVQEQLRLYDM 204
>gi|56549133 transmembrane anchor protein 1 isoform 2 [Homo sapiens]
Length = 177
Score = 342 bits (877), Expect = 1e-94
Identities = 167/169 (98%), Positives = 169/169 (100%)
Query: 1 MEAPAELLAALPALATALALLLAWLLVRRGAAASPEPARAPPEPAPPAEATGAPAPSRPC 60
MEAPAELLAALPALATALALLLAWLLVRRGAAASPEPARAPPEPAPPAEATGAPAPSRPC
Sbjct: 1 MEAPAELLAALPALATALALLLAWLLVRRGAAASPEPARAPPEPAPPAEATGAPAPSRPC 60
Query: 61 APEPAASPAGPEEPGEPAGLGELGEPAGPGEPEGPGDPAAAPAEAEEQAVEARQEEEQDL 120
APEPAASPAGPEEPGEPAGLGELGEPAGPGEPEGPGDPAAAPAEAEEQAVEARQEEEQDL
Sbjct: 61 APEPAASPAGPEEPGEPAGLGELGEPAGPGEPEGPGDPAAAPAEAEEQAVEARQEEEQDL 120
Query: 121 DGEKGPSSEGPEEEDGEGFSFKYSPGKLRGNQYKKMMTKEELEEEQRVQ 169
DGEKGPSSEGPEEEDGEGFSFKYSPGKLRGNQYKKMMTKEELEEEQR++
Sbjct: 121 DGEKGPSSEGPEEEDGEGFSFKYSPGKLRGNQYKKMMTKEELEEEQRIE 169
>gi|56549129 transmembrane anchor protein 1 isoform 3 [Homo sapiens]
Length = 170
Score = 341 bits (875), Expect = 2e-94
Identities = 167/170 (98%), Positives = 169/170 (99%)
Query: 1 MEAPAELLAALPALATALALLLAWLLVRRGAAASPEPARAPPEPAPPAEATGAPAPSRPC 60
MEAPAELLAALPALATALALLLAWLLVRRGAAASPEPARAPPEPAPPAEATGAPAPSRPC
Sbjct: 1 MEAPAELLAALPALATALALLLAWLLVRRGAAASPEPARAPPEPAPPAEATGAPAPSRPC 60
Query: 61 APEPAASPAGPEEPGEPAGLGELGEPAGPGEPEGPGDPAAAPAEAEEQAVEARQEEEQDL 120
APEPAASPAGPEEPGEPAGLGELGEPAGPGEPEGPGDPAAAPAEAEEQAVEARQEEEQDL
Sbjct: 61 APEPAASPAGPEEPGEPAGLGELGEPAGPGEPEGPGDPAAAPAEAEEQAVEARQEEEQDL 120
Query: 121 DGEKGPSSEGPEEEDGEGFSFKYSPGKLRGNQYKKMMTKEELEEEQRVQK 170
DGEKGPSSEGPEEEDGEGFSFKYSPGKLRGNQYKKMMTKEELEEEQR ++
Sbjct: 121 DGEKGPSSEGPEEEDGEGFSFKYSPGKLRGNQYKKMMTKEELEEEQRTEE 170
>gi|155030232 proline, glutamic acid and leucine rich protein 1
[Homo sapiens]
Length = 1130
Score = 55.5 bits (132), Expect = 3e-08
Identities = 46/154 (29%), Positives = 62/154 (40%), Gaps = 14/154 (9%)
Query: 32 AASPEPARAPPEPA--PPAEATGAPAPSRPCAPEPAASPAGPEEPGEPAGLGELGEPAGP 89
A + P +PP PA P E AP P P P P P P P L G P G
Sbjct: 812 APTGPPTASPPVPAKEEPEELPAAPGPLPPPPPPPPPVPGPVTLP--PPQLVPEGTPGGG 869
Query: 90 GEPE----------GPGDPAAAPAEAEEQAVEARQEEEQDLDGEKGPSSEGPEEEDGEGF 139
G P D E EE+ E +EEE+D + E+ E EEE+ E
Sbjct: 870 GPPALEEDLTVININSSDEEEEEEEEEEEEEEEEEEEEEDFEEEEEDEEEYFEEEEEEEE 929
Query: 140 SFKYSPGKLRGNQYKKMMTKEELEEEQRVQKEQL 173
F+ + G ++ ++E EEE+ + E L
Sbjct: 930 EFEEEFEEEEGELEEEEEEEDEEEEEELEEVEDL 963
Score = 35.8 bits (81), Expect = 0.026
Identities = 42/155 (27%), Positives = 57/155 (36%), Gaps = 20/155 (12%)
Query: 30 GAAASPEPARAPPEPAPPAEATGAPAPSRPCAPEPAASP-AGPEEPGEPAGLGELGEPAG 88
G A APP P P P P P + P PE EP L E+ EP
Sbjct: 966 GTAGGEVEEGAPPPPTLP-----------PALPPPESPPKVQPEPEPEPGLLLEVEEPGT 1014
Query: 89 PGEPEGPGDPAAAPAEAEEQAVEARQEEE-------QDLDGEKGPSSEGPEEEDGEGFSF 141
E P AP Q R+ E Q+L E+ + EE+ E S
Sbjct: 1015 EEERGADTAPTLAPEALPSQGEVEREGESPAAGPPPQELVEEEPSAPPTLLEEETEDGSD 1074
Query: 142 KYSPGKLRGNQYKKMMTKEELEEEQRVQKEQLAAI 176
K P + ++M T+ E E Q +++ AA+
Sbjct: 1075 KVQPPPETPAE-EEMETETEAEALQEKEQDDTAAM 1108
Score = 33.9 bits (76), Expect = 0.098
Identities = 18/55 (32%), Positives = 22/55 (40%), Gaps = 4/55 (7%)
Query: 34 SPEPARAPP----EPAPPAEATGAPAPSRPCAPEPAASPAGPEEPGEPAGLGELG 84
+P P RAPP P P + + P P P+A P PG P LG
Sbjct: 656 APSPFRAPPFHPPGPMPSVGSMPSAGPMPSAGPMPSAGPVPSARPGPPTTANHLG 710
Score = 30.8 bits (68), Expect = 0.83
Identities = 36/132 (27%), Positives = 40/132 (30%), Gaps = 39/132 (29%)
Query: 27 VRRGAAASPE--PARAPPEPAPPAEATGAPAP-------------------SRPCAPEPA 65
V GA P PA PPE P + P P + APE
Sbjct: 972 VEEGAPPPPTLPPALPPPESPPKVQPEPEPEPGLLLEVEEPGTEEERGADTAPTLAPEAL 1031
Query: 66 ASPAGPEEPGEPAGLGELGEPAGPGEPEGPGD---------------PAAAPAEAE---E 107
S E GE G + EP P P PAE E E
Sbjct: 1032 PSQGEVEREGESPAAGPPPQELVEEEPSAPPTLLEEETEDGSDKVQPPPETPAEEEMETE 1091
Query: 108 QAVEARQEEEQD 119
EA QE+EQD
Sbjct: 1092 TEAEALQEKEQD 1103
>gi|110832843 TBP-associated factor 4 [Homo sapiens]
Length = 1085
Score = 55.1 bits (131), Expect = 4e-08
Identities = 43/111 (38%), Positives = 50/111 (45%), Gaps = 15/111 (13%)
Query: 31 AAASPEPARAPPEPAPPAEATGA--------PAPSRPCAPEPAASPAGPEEPGEPAGLGE 82
A A PA APP P PPA AT A P + P P PAA+ G PA
Sbjct: 260 APAPAAPAAAPPPP-PPAPATLARPPGHPAGPPTAAPAVPPPAAAQNGGSAGAAPAPAPA 318
Query: 83 LGEPAGPGEPEGPGDPAAAP-----AEAEEQAVEARQEEEQDLDGEKGPSS 128
G PAG GPG AAAP AE+ ++ V+A Q L GP+S
Sbjct: 319 AGGPAGVSGQPGPGAAAAAPAPGVKAESPKRVVQAAPPAAQTL-AASGPAS 368
Score = 48.9 bits (115), Expect = 3e-06
Identities = 36/95 (37%), Positives = 41/95 (43%), Gaps = 9/95 (9%)
Query: 28 RRGAAASPEPARAPPEPAPPAEATGAP--APSRPCAPEPAASP--AGPEE----PGEPAG 79
+R SP P PAPPA P + CAP PAA+ AGPE P +PAG
Sbjct: 103 QRPGPPSPRRPLVPAGPAPPAAKLRPPPEGSAGSCAPVPAAAAVAAGPEPAPAGPAKPAG 162
Query: 80 LGELGEPAGPGEPEGPGDPAAAPAEAEEQAVEARQ 114
L AGPG GPG P P + A Q
Sbjct: 163 PAALAARAGPGPGPGPG-PGPGPGPGKPAGPGAAQ 196
Score = 45.8 bits (107), Expect = 3e-05
Identities = 32/83 (38%), Positives = 36/83 (43%), Gaps = 7/83 (8%)
Query: 26 LVRRGAAASPEPARAPPEPAPPAEATGAPAPSRPCAPEPAASPAGPEEPGEPAGLGELGE 85
LV G A R PPE + + A A + PEPA PAGP +P PA L
Sbjct: 114 LVPAGPAPPAAKLRPPPEGSAGSCAPVPAAAAVAAGPEPA--PAGPAKPAGPAALAARAG 171
Query: 86 PA-----GPGEPEGPGDPAAAPA 103
P GPG GPG PA A
Sbjct: 172 PGPGPGPGPGPGPGPGKPAGPGA 194
Score = 43.5 bits (101), Expect = 1e-04
Identities = 47/115 (40%), Positives = 53/115 (46%), Gaps = 28/115 (24%)
Query: 1 MEAPAELLAALPALATALALLLAWLLVRRGAAAS---PEPA------RAPP---EPAPPA 48
+ A LL + A A A++L V G AA P+PA + PP APPA
Sbjct: 198 LNGSAALLNSHHAAAPAVSL------VNNGPAALLPLPKPAAPGTVIQTPPFVGAAAPPA 251
Query: 49 EATGAPAPSRPCAPEPAASPAGPEEPGEPAGLGELGEPAGPGEPEGPGDPAAAPA 103
A APS P AP PAA A P P PA L P PG P GP P AAPA
Sbjct: 252 PA----APSPPAAPAPAAPAAAPP-PPPPAP-ATLARP--PGHPAGP--PTAAPA 296
Score = 38.5 bits (88), Expect = 0.004
Identities = 22/57 (38%), Positives = 24/57 (42%), Gaps = 7/57 (12%)
Query: 44 PAPPAEATGAPAPSRPCAPEPAASPAGPEEPGEPAGLGELGEPAGPGEPEGPGDPAA 100
PA PAE AP P A GP+ PG P+ P P P GP PAA
Sbjct: 75 PAAPAEGAPGAAPEPPPAGRARPGGGGPQRPGPPS-------PRRPLVPAGPAPPAA 124
Score = 37.4 bits (85), Expect = 0.009
Identities = 39/120 (32%), Positives = 42/120 (35%), Gaps = 11/120 (9%)
Query: 30 GAAASPEPAR-APPEPAPPAEAT-GAPAPSRPCAPEPAA--SPAGPEEPG---EPAGLGE 82
G AA E A A PEP P A G P RP P P PAGP P P G
Sbjct: 74 GPAAPAEGAPGAAPEPPPAGRARPGGGGPQRPGPPSPRRPLVPAGPAPPAAKLRPPPEGS 133
Query: 83 LGE----PAGPGEPEGPGDPAAAPAEAEEQAVEARQEEEQDLDGEKGPSSEGPEEEDGEG 138
G PA GP A PA+ A A + G GP + G G
Sbjct: 134 AGSCAPVPAAAAVAAGPEPAPAGPAKPAGPAALAARAGPGPGPGPGPGPGPGPGKPAGPG 193
Score = 30.8 bits (68), Expect = 0.83
Identities = 26/83 (31%), Positives = 29/83 (34%), Gaps = 1/83 (1%)
Query: 31 AAASPEPARAPPEPAPPAEATGAPAPSRPCAPEPAASPAGPEEPGEPA-GLGELGEPAGP 89
A+A+ AP P A A GA A+ AGP P E A G PAG
Sbjct: 35 ASAAHHHHLAPRTPEVRAAAAGALGNHVVSGSPAGAAGAGPAAPAEGAPGAAPEPPPAGR 94
Query: 90 GEPEGPGDPAAAPAEAEEQAVEA 112
P G G P V A
Sbjct: 95 ARPGGGGPQRPGPPSPRRPLVPA 117
>gi|111118994 brain-specific angiogenesis inhibitor 1 precursor [Homo
sapiens]
Length = 1584
Score = 53.1 bits (126), Expect = 2e-07
Identities = 36/96 (37%), Positives = 42/96 (43%), Gaps = 4/96 (4%)
Query: 32 AASPEPARAPPEPAPPAEATGAPAPSRPCAPEPAASPAGPEEPGEPA--GLGELGEPAG- 88
A SP P+R PP PP P P P P P P P EPA LG+ GEPA
Sbjct: 1390 ARSP-PSRQPPSGGPPEAPPAQPPPPPPPPPPPPQQPLPPPPNLEPAPPSLGDPGEPAAH 1448
Query: 89 PGEPEGPGDPAAAPAEAEEQAVEARQEEEQDLDGEK 124
PG GP A ++E R+ +LD EK
Sbjct: 1449 PGPSTGPSTKNENVATLSVSSLERRKSRYAELDFEK 1484
>gi|217416350 cask-interacting protein 2 isoform b [Homo sapiens]
Length = 1120
Score = 53.1 bits (126), Expect = 2e-07
Identities = 40/131 (30%), Positives = 47/131 (35%), Gaps = 31/131 (23%)
Query: 26 LVRRGAAASPEPARAPPE--------------PAPPAEATGAPAPSRPCAPEPAASPAGP 71
LVR + +P PAR P P PP + PS P P GP
Sbjct: 756 LVRTSPSVTPTPARGTPRSQSFALRARRKGPPPPPPKRLSSVSGPSPE--PPPLDESPGP 813
Query: 72 EEPGEPAGLGELGEPAGPGEPEGPGDPAAAPAEAEEQAVEARQEEEQDLDGEKGPSSEGP 131
+E L EPAGP EP GP PA ++ EE+ E GP P
Sbjct: 814 KEGATGPRRRTLSEPAGPSEPPGPPAPAGPASDTEEE--------------EPGPEGTPP 859
Query: 132 EE-EDGEGFSF 141
GEG F
Sbjct: 860 SRGSSGEGLPF 870
Score = 42.4 bits (98), Expect = 3e-04
Identities = 30/83 (36%), Positives = 33/83 (39%), Gaps = 5/83 (6%)
Query: 34 SPEPARAPPEPAPPAEATGAPAPSRPCAPEPA--ASPAGPEEPGEPAGLGELGEPAGPGE 91
SPEP PP P GA P R EPA + P GP P PA E EP G
Sbjct: 801 SPEP---PPLDESPGPKEGATGPRRRTLSEPAGPSEPPGPPAPAGPASDTEEEEPGPEGT 857
Query: 92 PEGPGDPAAAPAEAEEQAVEARQ 114
P G AEE + +Q
Sbjct: 858 PPSRGSSGEGLPFAEEGNLTIKQ 880
Score = 41.6 bits (96), Expect = 5e-04
Identities = 31/82 (37%), Positives = 35/82 (42%), Gaps = 14/82 (17%)
Query: 31 AAASPEPARAPPEP----APPAEATGAPAPSR--------PCAPEPAASPAGPEEPGEPA 78
A+A+P PA P P +PPA + P PS P AP PA P P PG
Sbjct: 930 ASATPGPAAPLPSPTPGESPPASSLPQPEPSSLPAQGVPTPLAPSPAMQPPVPPCPG--P 987
Query: 79 GLGELGEPAGPGEPEGPGDPAA 100
GL GE E P PAA
Sbjct: 988 GLESSAASRWNGETEPPAAPAA 1009
Score = 34.3 bits (77), Expect = 0.075
Identities = 41/146 (28%), Positives = 56/146 (38%), Gaps = 18/146 (12%)
Query: 2 EAPAELLAALPALATALALLLAWLLVRRGAAASPEPARAPPEPAPPAEATGAPA-PSRPC 60
E PA A P L T L+ L A PEP PP +P E+ GA + S
Sbjct: 573 EGPA---TAGPRLLTFQGSELSPELQAAMAGGGPEPLPLPPARSPSQESIGARSRGSGHS 629
Query: 61 APEPAASPAGPEEPGEPAGLGELGEPAGPGEPEGPGDPAAAPAEAEEQAVEARQEEEQDL 120
+PA P+G G+P+ E P G P P ++ P + V +
Sbjct: 630 QEQPAPQPSG----GDPSPPQERNLPEGTERP--PKLCSSLPGQGPPPYV--------FM 675
Query: 121 DGEKGPSSEGPEEEDGEGFSFKYSPG 146
+ PSS P G ++F Y G
Sbjct: 676 YPQGSPSSPAPGPPPGAPWAFSYLAG 701
Score = 30.4 bits (67), Expect = 1.1
Identities = 25/84 (29%), Positives = 31/84 (36%), Gaps = 4/84 (4%)
Query: 33 ASPEPARAPPEPAPPAEATGAPAPSRPCAPEPAASPAGPEEPGEPAG---LGELGEPAGP 89
A P PP PA PA T P P P+ +G P G + + +PAGP
Sbjct: 829 AGPSEPPGPPAPAGPASDTEEEEPG-PEGTPPSRGSSGEGLPFAEEGNLTIKQRPKPAGP 887
Query: 90 GEPEGPGDPAAAPAEAEEQAVEAR 113
E P P E V+ R
Sbjct: 888 PPRETPVPPGLDFNLTESDTVKRR 911
Score = 28.5 bits (62), Expect = 4.1
Identities = 21/63 (33%), Positives = 24/63 (38%), Gaps = 5/63 (7%)
Query: 35 PEPARAPPEPAPPAEATGAPAPSRPCAPEPAASPAGPEEPGEPAGLGELGEPAG--PGEP 92
P+ + + P P PP GAP A PA P P L G G GE
Sbjct: 677 PQGSPSSPAPGPPP---GAPWAFSYLAGPPATPPDPPRPKRRSHSLSRPGPTEGDAEGEA 733
Query: 93 EGP 95
EGP
Sbjct: 734 EGP 736
>gi|217416347 cask-interacting protein 2 isoform a [Homo sapiens]
Length = 1202
Score = 53.1 bits (126), Expect = 2e-07
Identities = 40/131 (30%), Positives = 47/131 (35%), Gaps = 31/131 (23%)
Query: 26 LVRRGAAASPEPARAPPE--------------PAPPAEATGAPAPSRPCAPEPAASPAGP 71
LVR + +P PAR P P PP + PS P P GP
Sbjct: 838 LVRTSPSVTPTPARGTPRSQSFALRARRKGPPPPPPKRLSSVSGPSPE--PPPLDESPGP 895
Query: 72 EEPGEPAGLGELGEPAGPGEPEGPGDPAAAPAEAEEQAVEARQEEEQDLDGEKGPSSEGP 131
+E L EPAGP EP GP PA ++ EE+ E GP P
Sbjct: 896 KEGATGPRRRTLSEPAGPSEPPGPPAPAGPASDTEEE--------------EPGPEGTPP 941
Query: 132 EE-EDGEGFSF 141
GEG F
Sbjct: 942 SRGSSGEGLPF 952
Score = 42.4 bits (98), Expect = 3e-04
Identities = 30/83 (36%), Positives = 33/83 (39%), Gaps = 5/83 (6%)
Query: 34 SPEPARAPPEPAPPAEATGAPAPSRPCAPEPA--ASPAGPEEPGEPAGLGELGEPAGPGE 91
SPEP PP P GA P R EPA + P GP P PA E EP G
Sbjct: 883 SPEP---PPLDESPGPKEGATGPRRRTLSEPAGPSEPPGPPAPAGPASDTEEEEPGPEGT 939
Query: 92 PEGPGDPAAAPAEAEEQAVEARQ 114
P G AEE + +Q
Sbjct: 940 PPSRGSSGEGLPFAEEGNLTIKQ 962
Score = 41.6 bits (96), Expect = 5e-04
Identities = 31/82 (37%), Positives = 35/82 (42%), Gaps = 14/82 (17%)
Query: 31 AAASPEPARAPPEP----APPAEATGAPAPSR--------PCAPEPAASPAGPEEPGEPA 78
A+A+P PA P P +PPA + P PS P AP PA P P PG
Sbjct: 1012 ASATPGPAAPLPSPTPGESPPASSLPQPEPSSLPAQGVPTPLAPSPAMQPPVPPCPG--P 1069
Query: 79 GLGELGEPAGPGEPEGPGDPAA 100
GL GE E P PAA
Sbjct: 1070 GLESSAASRWNGETEPPAAPAA 1091
Score = 34.3 bits (77), Expect = 0.075
Identities = 41/146 (28%), Positives = 56/146 (38%), Gaps = 18/146 (12%)
Query: 2 EAPAELLAALPALATALALLLAWLLVRRGAAASPEPARAPPEPAPPAEATGAPA-PSRPC 60
E PA A P L T L+ L A PEP PP +P E+ GA + S
Sbjct: 655 EGPA---TAGPRLLTFQGSELSPELQAAMAGGGPEPLPLPPARSPSQESIGARSRGSGHS 711
Query: 61 APEPAASPAGPEEPGEPAGLGELGEPAGPGEPEGPGDPAAAPAEAEEQAVEARQEEEQDL 120
+PA P+G G+P+ E P G P P ++ P + V +
Sbjct: 712 QEQPAPQPSG----GDPSPPQERNLPEGTERP--PKLCSSLPGQGPPPYV--------FM 757
Query: 121 DGEKGPSSEGPEEEDGEGFSFKYSPG 146
+ PSS P G ++F Y G
Sbjct: 758 YPQGSPSSPAPGPPPGAPWAFSYLAG 783
Score = 30.4 bits (67), Expect = 1.1
Identities = 25/84 (29%), Positives = 31/84 (36%), Gaps = 4/84 (4%)
Query: 33 ASPEPARAPPEPAPPAEATGAPAPSRPCAPEPAASPAGPEEPGEPAG---LGELGEPAGP 89
A P PP PA PA T P P P+ +G P G + + +PAGP
Sbjct: 911 AGPSEPPGPPAPAGPASDTEEEEPG-PEGTPPSRGSSGEGLPFAEEGNLTIKQRPKPAGP 969
Query: 90 GEPEGPGDPAAAPAEAEEQAVEAR 113
E P P E V+ R
Sbjct: 970 PPRETPVPPGLDFNLTESDTVKRR 993
Score = 28.5 bits (62), Expect = 4.1
Identities = 21/63 (33%), Positives = 24/63 (38%), Gaps = 5/63 (7%)
Query: 35 PEPARAPPEPAPPAEATGAPAPSRPCAPEPAASPAGPEEPGEPAGLGELGEPAG--PGEP 92
P+ + + P P PP GAP A PA P P L G G GE
Sbjct: 759 PQGSPSSPAPGPPP---GAPWAFSYLAGPPATPPDPPRPKRRSHSLSRPGPTEGDAEGEA 815
Query: 93 EGP 95
EGP
Sbjct: 816 EGP 818
>gi|32455273 WNK lysine deficient protein kinase 2 [Homo sapiens]
Length = 2217
Score = 52.8 bits (125), Expect = 2e-07
Identities = 46/129 (35%), Positives = 52/129 (40%), Gaps = 25/129 (19%)
Query: 30 GAAASPEPARAPPEP--------APPAEATGAPAPSRPCAPEPAASPAGPEEPGEPAGLG 81
G A+ P PP+P A RP AP PAA A P PG PA G
Sbjct: 56 GLEAAEAPGPQPPQPLQRRVLLLCKTRRLIAERARGRPAAPAPAALVAQPGAPGAPADAG 115
Query: 82 ELGEPAGPGEPEGPGDPAAAPAEA---------EEQAVEARQEEEQDLDGEKGPS----S 128
EP G EP GP DP AA E EE A R+E+E + + P
Sbjct: 116 P--EPVGTQEP-GP-DPIAAAVETAPAPDGGPREEAAATVRKEDEGAAEAKPEPGRTRRD 171
Query: 129 EGPEEEDGE 137
E EEED E
Sbjct: 172 EPEEEEDDE 180
Score = 40.8 bits (94), Expect = 8e-04
Identities = 38/108 (35%), Positives = 49/108 (45%), Gaps = 16/108 (14%)
Query: 29 RGAAASPEPARAPPEPAPPAEATGAPAPSRPCAPEPAASPAGPEEPGEPAGLGELGEPAG 88
RG A+P PA +P P GAPA PE P G +EPG P + E A
Sbjct: 90 RGRPAAPAPAALVAQPGAP----GAPAD---AGPE----PVGTQEPG-PDPIAAAVETA- 136
Query: 89 PGEPEGPGDPAAAPAEAEEQ-AVEARQEEEQDLDGEKGPSSEGPEEED 135
P GP + AAA E++ A EA+ E + E P E +E+D
Sbjct: 137 PAPDGGPREEAAATVRKEDEGAAEAKPEPGRTRRDE--PEEEEDDEDD 182
Score = 40.8 bits (94), Expect = 8e-04
Identities = 30/100 (30%), Positives = 38/100 (38%), Gaps = 1/100 (1%)
Query: 27 VRRGAAASPEPARAPPEPAPPAEATGAPAPSRPCAPEPAASPAGPEEPGEPAGLGELGEP 86
V+ A P+PA PP+P P + P P+ P P P P +P P +P
Sbjct: 932 VQNMRATPPQPA-LPPQPTLPPQPVLPPQPTLPPQPVLPPQPTRPPQPVLPPQPMLPPQP 990
Query: 87 AGPGEPEGPGDPAAAPAEAEEQAVEARQEEEQDLDGEKGP 126
P +P P P EQA A Q L G P
Sbjct: 991 VLPPQPALPVRPEPLQPHLPEQAAPAATPGSQILLGHPAP 1030
Score = 38.9 bits (89), Expect = 0.003
Identities = 50/187 (26%), Positives = 64/187 (34%), Gaps = 34/187 (18%)
Query: 1 MEAPAELLAALPALATALALLLAWLLVRRGAAASPEPARAPPEPAPPAEATGAPAPSRPC 60
M P +L PAL L L + AA+P PAP A A P+ P
Sbjct: 985 MLPPQPVLPPQPALPVRPEPLQPHLPEQAAPAATPGSQILLGHPAPYAVDVAAQVPTVPV 1044
Query: 61 APEPAASPAGPEE---------PGEPAGLGELG--------------EPAGPGEPEGPGD 97
P SP PE P P+ L + PA P P GPG
Sbjct: 1045 PPAAVLSPPLPEVLLPAAPELLPQFPSSLATVSASVQSVPTQTATLLPPANPPLPGGPG- 1103
Query: 98 PAAAPAEAEEQAVEARQEEEQDLDGEKG-----PSSEGPEEEDGEGFSFK----YSPGKL 148
A+P + VE QEE+ D G S G + G+ S + G+L
Sbjct: 1104 -IASPCPTVQLTVEPVQEEQASQDKPPGLPQSCESYGGSDVTSGKELSDSCEGAFGGGRL 1162
Query: 149 RGNQYKK 155
G +K
Sbjct: 1163 EGRAARK 1169
Score = 37.0 bits (84), Expect = 0.012
Identities = 29/75 (38%), Positives = 34/75 (45%), Gaps = 6/75 (8%)
Query: 29 RGAAASPEPARAP-PEPAP----PAEATGAPAPSRPCAPEPAASPAGPEEPGEPAGLGEL 83
R A+A EP P PEP+P P A G PAP P A A S A + P P G
Sbjct: 1466 RDASAPREPLPPPAPEPSPHSGTPQPALGQPAPLLPAA-VGAVSLATSQLPSPPLGPTVP 1524
Query: 84 GEPAGPGEPEGPGDP 98
+P E +G G P
Sbjct: 1525 PQPPSALESDGEGPP 1539
Score = 35.4 bits (80), Expect = 0.034
Identities = 28/76 (36%), Positives = 30/76 (39%), Gaps = 6/76 (7%)
Query: 32 AASPEPARAPPEPAPPAEATGAPAPS-RPCAPEPAASPAGPEEPGEPAGLGELGEPAGPG 90
AAS A AP EP PP AP PS P+PA P P G L P
Sbjct: 1462 AASTRDASAPREPLPPP----APEPSPHSGTPQPALGQPAPLLPA-AVGAVSLATSQLPS 1516
Query: 91 EPEGPGDPAAAPAEAE 106
P GP P P+ E
Sbjct: 1517 PPLGPTVPPQPPSALE 1532
Score = 33.9 bits (76), Expect = 0.098
Identities = 22/63 (34%), Positives = 28/63 (44%), Gaps = 8/63 (12%)
Query: 32 AASPEPARAPPEPAPPAEATGAPAPSRPCAPEPAASPAGPEEPGEPAGLGELGEPAGPGE 91
A P APP P P+ +P P+ A+PA P EPA G + GPG
Sbjct: 1371 AGPSNPPGAPPAPLAPS------SPPVTALPQDGAAPATSTMP-EPAS-GTASQAGGPGT 1422
Query: 92 PEG 94
P+G
Sbjct: 1423 PQG 1425
Score = 29.6 bits (65), Expect = 1.9
Identities = 20/66 (30%), Positives = 23/66 (34%)
Query: 37 PARAPPEPAPPAEATGAPAPSRPCAPEPAASPAGPEEPGEPAGLGELGEPAGPGEPEGPG 96
P A P P P A P +P P A + G PA L L P P +P
Sbjct: 732 PPLAQPTPLPQVLAPQPVVPLQPVPPHLPPYLAPASQVGAPAQLKPLQMPQAPLQPLAQV 791
Query: 97 DPAAAP 102
P P
Sbjct: 792 PPQMPP 797
Score = 29.3 bits (64), Expect = 2.4
Identities = 18/60 (30%), Positives = 23/60 (38%), Gaps = 6/60 (10%)
Query: 73 EPGEPAGLGELGEPAGPGEPEGPGDPAAAPAEAEEQAVEARQEEEQDLDGEKGPSSEGPE 132
EPG AG PAG EP VE+ QEE L+ + P + P+
Sbjct: 16 EPGRGAG------PAGMAEPRAKAARPGPQRFLRRSVVESDQEEPPGLEAAEAPGPQPPQ 69
>gi|78190492 retinitis pigmentosa GTPase regulator isoform C [Homo
sapiens]
Length = 1152
Score = 52.0 bits (123), Expect = 3e-07
Identities = 37/108 (34%), Positives = 53/108 (49%), Gaps = 11/108 (10%)
Query: 70 GPEEPGEPAGLGELGEPAGPGEPEGPGDPAAAPAEAEEQAVEARQEE-----EQDLDGEK 124
G EE GE G E GE G E EG G+ E EE E +EE E++ +GE+
Sbjct: 948 GEEEEGEWEGEEEEGEGEGEEEGEGEGEEGEGEGEEEEGEGEGEEEEGEEEGEEEGEGEE 1007
Query: 125 GPSSEGPEEEDGEGFSFKYSPGKLRGNQYKKMMTKEELEEEQRVQKEQ 172
EG EEE+GE G++ G + + +EE EEE ++++
Sbjct: 1008 EGEGEGEEEEEGE------VEGEVEGEEGEGEGEEEEGEEEGEEREKE 1049
Score = 47.0 bits (110), Expect = 1e-05
Identities = 37/104 (35%), Positives = 49/104 (47%), Gaps = 2/104 (1%)
Query: 70 GPEEPGEPAGLGELGEPAGPGEP-EGPGDPAAAPAEAEEQAVEARQEEEQDLDGEKGPSS 128
G EE E G GE E G GE EG G+ E EE+ E EEE + +GE+G
Sbjct: 921 GEEEGEEGEGEGEEEEGEGEGEDGEGEGEEEEGEWEGEEEEGEGEGEEEGEGEGEEGEGE 980
Query: 129 EGPEEEDGEGFSFK-YSPGKLRGNQYKKMMTKEELEEEQRVQKE 171
EE +GEG + G+ G ++ + E EEE V+ E
Sbjct: 981 GEEEEGEGEGEEEEGEEEGEEEGEGEEEGEGEGEEEEEGEVEGE 1024
Score = 45.1 bits (105), Expect = 4e-05
Identities = 36/101 (35%), Positives = 48/101 (47%), Gaps = 5/101 (4%)
Query: 73 EPGEPAGLGELGEPAGPGEPEGPGDPAAAPAEAEEQAVEARQEEEQDLDG-EKGPSSEGP 131
E GE G E GE G E EG G+ E EE+ +EEE + G E+G EG
Sbjct: 872 EEGEGEGEEEEGEGEGEEEGEGEGEEEEGEGEGEEEGEGEGEEEEGEGKGEEEGEEGEGE 931
Query: 132 -EEEDGEGFSFKYSPGKLRGNQYKKMMTKEELEEEQRVQKE 171
EEE+GEG + G+ G + + EE E E ++E
Sbjct: 932 GEEEEGEG---EGEDGEGEGEEEEGEWEGEEEEGEGEGEEE 969
Score = 42.4 bits (98), Expect = 3e-04
Identities = 26/67 (38%), Positives = 33/67 (49%), Gaps = 1/67 (1%)
Query: 72 EEPGEPAGLGELGEPAGPGEPEGPGDPAAAPAEAEEQAVEARQEEEQDLDGEKGPSSEGP 131
EE GE G E GE G E EG G+ + EE+ E E E++ +G EG
Sbjct: 888 EEEGEGEGEEEEGEGEGEEEGEGEGEEEEGEGKGEEEGEEGEGEGEEEEGEGEGEDGEGE 947
Query: 132 -EEEDGE 137
EEE+GE
Sbjct: 948 GEEEEGE 954
Score = 40.8 bits (94), Expect = 8e-04
Identities = 37/132 (28%), Positives = 59/132 (44%), Gaps = 20/132 (15%)
Query: 70 GPEEPGEPAGLGELGEPAGPGEPEGPGDPAAAPAEAEEQAVEARQEE---EQDLDGEKGP 126
G EE G+ E E G G+ EG G+ E EE E ++EE +++ E+G
Sbjct: 738 GEEEEGDRE---EEEEKEGEGKEEGEGEEVEGEREKEEG--ERKKEERAGKEEKGEEEGD 792
Query: 127 SSEGPEEEDGEGFSFKYSPGKLRGNQYKKMMTKEELEEEQRVQKEQLAAIFKLMKDNKET 186
EG EEE K G++ G + ++ + E EEE+ +E+ E
Sbjct: 793 QGEGEEEETEGRGEEKEEGGEVEGGEVEEGKGEREEEEEEGEGEEE------------EG 840
Query: 187 FGEMSDGDVQEQ 198
GE +G+ +E+
Sbjct: 841 EGEEEEGEGEEE 852
Score = 40.8 bits (94), Expect = 8e-04
Identities = 35/105 (33%), Positives = 49/105 (46%), Gaps = 6/105 (5%)
Query: 70 GPEEPGEPAGLGELGEPAGPGEPEGPGDPAAAPAEAEEQAV-EARQEEEQDLDGE-KGPS 127
G E E G GE E G GE E + E EE+ E +EEE +++GE +G
Sbjct: 970 GEGEGEEGEGEGEEEEGEGEGEEEEGEEEGEEEGEGEEEGEGEGEEEEEGEVEGEVEGEE 1029
Query: 128 SEGP-EEEDGEGFSFKYSPGKLRGNQYKKMMTKEELEEEQRVQKE 171
EG EEE+GE + + G + +EE EEE+ +E
Sbjct: 1030 GEGEGEEEEGEE---EGEEREKEGEGEENRRNREEEEEEEGKYQE 1071
Score = 39.3 bits (90), Expect = 0.002
Identities = 42/148 (28%), Positives = 61/148 (41%), Gaps = 24/148 (16%)
Query: 73 EPGEP-AGLGELGEPAGPGEPEGPGDPAAAPAEAEEQAVEARQE---------------- 115
E GE G GE+ P G GE E + EEQ + R++
Sbjct: 675 EKGEKDKGRGEMERP-GEGEKELAEKEEWKKRDGEEQEQKEREQGHQKERNQEMEEGGEE 733
Query: 116 -----EEQDLDGEKGPSSEGPEEEDGEGFSFKYSPGKLRGNQYKKMMT-KEELEEEQRVQ 169
EE++ D E+ EG +E+GEG + K G + K+ KEE EE+ Q
Sbjct: 734 EHGEGEEEEGDREEEEEKEGEGKEEGEGEEVEGEREKEEGERKKEERAGKEEKGEEEGDQ 793
Query: 170 KEQLAAIFKLMKDNKETFGEMSDGDVQE 197
E + + KE GE+ G+V+E
Sbjct: 794 GEGEEEETEGRGEEKEEGGEVEGGEVEE 821
Score = 39.3 bits (90), Expect = 0.002
Identities = 38/129 (29%), Positives = 60/129 (46%), Gaps = 4/129 (3%)
Query: 72 EEPGEPAGLGELGEPAGPGEPEGP-GDPAAAPAEAEEQAVEARQEEEQDLDGEKGPSSEG 130
EE GE G GE+ E G E E G+ E EE+ E +EE + E+G EG
Sbjct: 809 EEGGEVEG-GEVEEGKGEREEEEEEGEGEEEEGEGEEEEGEGEEEEGEGKGEEEGEEGEG 867
Query: 131 PEE-EDGEGFSFKYSPGKLRGNQYKKMMTKEELEEEQRVQKEQLAAIFKLMKDNKETFGE 189
EE E+GEG + G+ G + + +EE E + ++ + + + E GE
Sbjct: 868 EEEGEEGEG-EGEEEEGEGEGEEEGEGEGEEEEGEGEGEEEGEGEGEEEEGEGKGEEEGE 926
Query: 190 MSDGDVQEQ 198
+G+ +E+
Sbjct: 927 EGEGEGEEE 935
Score = 38.5 bits (88), Expect = 0.004
Identities = 36/105 (34%), Positives = 50/105 (47%), Gaps = 12/105 (11%)
Query: 72 EEPGEPAGLGELGEPAGPGEP-----EGPGDPAAAPAEAEEQAVEARQEEEQDLDGEKGP 126
EE GE G E GE G GE EG G+ E E+ E +EEE + +GE+
Sbjct: 905 EEEGEGEGEEEEGE--GKGEEEGEEGEGEGEEEEGEGEGEDGEGEG-EEEEGEWEGEE-E 960
Query: 127 SSEGPEEEDGEGFSFKYSPGKLRGNQYKKMMTKEELEEEQRVQKE 171
EG EE+GEG + G+ G + + EE E E+ ++E
Sbjct: 961 EGEGEGEEEGEG---EGEEGEGEGEEEEGEGEGEEEEGEEEGEEE 1002
Score = 37.7 bits (86), Expect = 0.007
Identities = 39/132 (29%), Positives = 54/132 (40%), Gaps = 18/132 (13%)
Query: 70 GPEEPGE---PAGLGELGEPAGPGEPEGPGDPAAAPAEAEEQAVEARQEEEQDLDGEKGP 126
G EE GE G GE E G GE EG + E EE E +EE + E+G
Sbjct: 835 GEEEEGEGEEEEGEGEEEEGEGKGEEEG--EEGEGEEEGEEGEGEGEEEEGEGEGEEEGE 892
Query: 127 SSEGPEEEDGEGFSFKYSPGKLRGNQYKKMMTKEELEEEQRVQKEQLAAIFKLMKDNKET 186
EE +GEG G+ G + + EE EE + E+ + E
Sbjct: 893 GEGEEEEGEGEG----EEEGEGEGEEEEGEGKGEEEGEEGEGEGEE---------EEGEG 939
Query: 187 FGEMSDGDVQEQ 198
GE +G+ +E+
Sbjct: 940 EGEDGEGEGEEE 951
Score = 34.7 bits (78), Expect = 0.058
Identities = 30/80 (37%), Positives = 36/80 (45%), Gaps = 14/80 (17%)
Query: 69 AGPEEPGEPAG---LGELGEPAGPGEPEGPG------DPAAAPAEAEEQAVEARQEEEQD 119
AG EE GE G GE E G GE + G + E EE+ E EEE+
Sbjct: 781 AGKEEKGEEEGDQGEGEEEETEGRGEEKEEGGEVEGGEVEEGKGEREEEEEEGEGEEEEG 840
Query: 120 LDGEKGPSSEGP-EEEDGEG 138
+G EG EEE+GEG
Sbjct: 841 ----EGEEEEGEGEEEEGEG 856
Score = 33.9 bits (76), Expect = 0.098
Identities = 36/108 (33%), Positives = 48/108 (44%), Gaps = 16/108 (14%)
Query: 72 EEPGEPAGLGELGEPAGPGEPEGPGDPAAAPAEAEEQAVEARQEEEQDLDGEKGPSSEGP 131
EE GE G E E G GE E G+ E E + E R+ E++ + E+G E
Sbjct: 1016 EEEGEVEGEVEGEEGEGEGEEE-EGEEEGEEREKEGEGEENRRNREEE-EEEEGKYQETG 1073
Query: 132 EEE----DGEGF--------SFKYSPGKLRGNQYKKMMTKEELEEEQR 167
EEE DGE + S KY GK + Q K + + +EQR
Sbjct: 1074 EEENERQDGEEYKKVSKIKGSVKY--GKHKTYQKKSVTNTQGNGKEQR 1119
>gi|78042577 MAP7 domain containing 1 [Homo sapiens]
Length = 841
Score = 52.0 bits (123), Expect = 3e-07
Identities = 47/170 (27%), Positives = 70/170 (41%), Gaps = 25/170 (14%)
Query: 27 VRRGAAASPEPARAPPEPAPPAE----------ATGAPAPSRPCAPEPAASPAGPEEPGE 76
VRR A P+ A PE ++ A +PAPS +P P A P + P E
Sbjct: 508 VRRKEEAKESPSAAGPEDKSQSKRRASNEKESAAPASPAPSPAPSPTP-APPQKEQPPAE 566
Query: 77 -PAGLGELGEPAGPGEPEGPGDPAAAPAEAEE----------QAVEARQEEEQDLDGEKG 125
P L P P P P P A + EE QA E R+ EEQ+ +
Sbjct: 567 TPTDAAVLTSPPAPAPPVTPSKPMAGTTDREEATRLLAEKRRQAREQREREEQERRLQAE 626
Query: 126 PSSEGPEEE---DGEGFSFKYSPGKLRGNQYKKMMTKEELEEEQRVQKEQ 172
EE+ + E + + + + R Q + + E EE++R+QK++
Sbjct: 627 RDKRMREEQLAREAEARAEREAEARRREEQEAREKAQAEQEEQERLQKQK 676
Score = 46.2 bits (108), Expect = 2e-05
Identities = 47/180 (26%), Positives = 72/180 (40%), Gaps = 18/180 (10%)
Query: 30 GAAASPEP-ARAPPEPAPPAEATGAPAPSRPCAPEPAASPAGPEEPGEPAGLGELGEPAG 88
GA A P AR PPEP P E +P P A P P P +L P
Sbjct: 10 GAGAPPAVVARTPPEPRPSPEGDPSPPPPPMSALVPDTPPDTPPAMKNATSSKQL--PLE 67
Query: 89 PGEPEGPGDPAAAPAEAEEQAVEARQEEEQDLDGEKGPSSEGPEEEDGEGFSFKYSPGKL 148
P P G P AP + E + EA+ P + GP + S + SP +
Sbjct: 68 PESPSGQVGPRPAPPQEESPSSEAKSRGPT-------PPAMGPRDARPPRRSSQPSPTAV 120
Query: 149 RGN-------QYKKMMTKEELEEEQRVQK-EQLAAIFKLMKDNKETFGEMSDGDVQEQLR 200
+ + KK + +L +E+R ++ + LAA + + +E + + +QE+ R
Sbjct: 121 PASDSPPTKQEVKKAGERHKLAKERREERAKYLAAKKAVWLEKEEKAKALREKQLQERRR 180
Score = 30.4 bits (67), Expect = 1.1
Identities = 30/109 (27%), Positives = 44/109 (40%), Gaps = 9/109 (8%)
Query: 28 RRGAAASPEP---ARAPPEPAPPAEAT-GAPAPS--RPCAPEPAASPAGPEEPGEPAGLG 81
R+ ASP A E +P ++A +P+ S RP +P P+ P P P+ G
Sbjct: 440 RQSLPASPRARLSASTASELSPKSKARPSSPSTSWHRPASPCPSPGPGHTLPPKPPSPRG 499
Query: 82 ELGEPAG--PGEPEGPGDPAAA-PAEAEEQAVEARQEEEQDLDGEKGPS 127
P G + E P+AA P + + A E+E PS
Sbjct: 500 TTASPKGRVRRKEEAKESPSAAGPEDKSQSKRRASNEKESAAPASPAPS 548
Score = 28.5 bits (62), Expect = 4.1
Identities = 25/95 (26%), Positives = 36/95 (37%), Gaps = 16/95 (16%)
Query: 44 PAPPAEATGAPAPSRPCAPEPAASPAGPE----EPGEPAGLGELGEPAGPGEPEGPGDPA 99
PA P A S +P+ A P+ P P P GPG P P+
Sbjct: 444 PASPRARLSASTASE-LSPKSKARPSSPSTSWHRPASPC------PSPGPGHTLPPKPPS 496
Query: 100 AAPAEAEEQAVEARQEEEQDLDGEKGPSSEGPEEE 134
A + R+EE ++ PS+ GPE++
Sbjct: 497 PRGTTASPKGRVRRKEE-----AKESPSAAGPEDK 526
>gi|156071470 hyperpolarization activated cyclic nucleotide-gated
potassium channel 2 [Homo sapiens]
Length = 889
Score = 51.6 bits (122), Expect = 5e-07
Identities = 39/117 (33%), Positives = 47/117 (40%), Gaps = 15/117 (12%)
Query: 28 RRGAAASPEPARAPPEPAPPAEATGAPAPSRPCAPEPAASPAGPEEPGEPAGLGELGEPA 87
R G + PA PP P PPA P P P AP P PA P+ P L E A
Sbjct: 9 RPGESPGATPAPGPPPPPPPAPPQQQPPPPPPPAPPPGPGPAPPQHPPRAEALPP--EAA 66
Query: 88 GPGEPEG-----------PGDP-AAAPAEAEEQAVEARQEEEQDLDGEKGPSSEGPE 132
G P G PG P AA+ A+ R E + G +GP + GP+
Sbjct: 67 DEGGPRGRLRSRDSSCGRPGTPGAASTAKGSPNGECGRGEPQCSPAGPEGP-ARGPK 122
Score = 42.4 bits (98), Expect = 3e-04
Identities = 35/88 (39%), Positives = 37/88 (42%), Gaps = 11/88 (12%)
Query: 26 LVRRGAAASPEPARAPPEPAPPAEATGAPAPSR-----PCAPEPAASPAGPEEPGEPAGL 80
LVRR P PA A P P PPA GAPA R P PAA AGP P L
Sbjct: 757 LVRR-PPPGPAPAAASPGPPPPASPPGAPASPRAPRTSPYGGLPAAPLAGPALPAR--RL 813
Query: 81 GELGEP---AGPGEPEGPGDPAAAPAEA 105
P + P P G PAA+ A
Sbjct: 814 SRASRPLSASQPSLPHGAPGPAASTRPA 841
Score = 39.3 bits (90), Expect = 0.002
Identities = 35/100 (35%), Positives = 43/100 (43%), Gaps = 13/100 (13%)
Query: 4 PAELLAALPALATALALL----LAWLLVRRGAAASPEPARAPPEPAPPAEATGAPAPSRP 59
P ++ +A+ L A A+ +A LV A SP R PP P P APA + P
Sbjct: 720 PPQVTSAIATLQQAAAMSFCPQVARPLVGPLALGSPRLVRRPP-PGP------APAAASP 772
Query: 60 CAPEPAASPAGPEEPGEPAGLGELGEPAGPGEPEGPGDPA 99
P PA+ P P P P G PA P GP PA
Sbjct: 773 GPPPPASPPGAPASPRAPRTSPYGGLPAAP--LAGPALPA 810
Score = 36.2 bits (82), Expect = 0.020
Identities = 25/81 (30%), Positives = 33/81 (40%), Gaps = 1/81 (1%)
Query: 46 PPAEATGAPAPSRPCAP-EPAASPAGPEEPGEPAGLGELGEPAGPGEPEGPGDPAAAPAE 104
P A +T +P+ C EP SPAGPE P + A G GPG A +E
Sbjct: 88 PGAASTAKGSPNGECGRGEPQCSPAGPEGPARGPKVSFSCRGAASGPAPGPGPAEEAGSE 147
Query: 105 AEEQAVEARQEEEQDLDGEKG 125
A E R + + + G
Sbjct: 148 EAGPAGEPRGSQASFMQRQFG 168
Score = 34.3 bits (77), Expect = 0.075
Identities = 31/98 (31%), Positives = 38/98 (38%), Gaps = 17/98 (17%)
Query: 12 PALATALALLLAWLLVRRGAAASPEPARAPPEPAPPAEATGAPAPSRPCAPEPAASPAGP 71
P + +A+A L ++ AA S P A P P A + P P PAA+ GP
Sbjct: 721 PQVTSAIATL------QQAAAMSFCPQVARPLVGPLALGSPRLVRRPPPGPAPAAASPGP 774
Query: 72 EEPGEPAGLGELGEPAGPGEPEG------PGDPAAAPA 103
P P G PA P P P P A PA
Sbjct: 775 PPPASPP-----GAPASPRAPRTSPYGGLPAAPLAGPA 807
Score = 31.2 bits (69), Expect = 0.64
Identities = 23/66 (34%), Positives = 24/66 (36%), Gaps = 9/66 (13%)
Query: 30 GAAASPEPARAPPEPAPPAEATGAPAPSRPCAPEPAASPAGPEEPGEPAGLGELGEPAGP 89
G EP +P P PA R A PA P EE G E AGP
Sbjct: 100 GECGRGEPQCSPAGPEGPARGPKVSFSCRGAASGPAPGPGPAEEAG--------SEEAGP 151
Query: 90 -GEPEG 94
GEP G
Sbjct: 152 AGEPRG 157
>gi|111118976 collagen, type II, alpha 1 isoform 1 precursor [Homo
sapiens]
Length = 1487
Score = 51.2 bits (121), Expect = 6e-07
Identities = 42/128 (32%), Positives = 51/128 (39%), Gaps = 22/128 (17%)
Query: 30 GAAASPEPARAPPEPAPP--------------AEATGAPAPSRPCAPEPAASPAGPE-EP 74
G SP PA A P A A G P P P P+ A P GP+ +
Sbjct: 396 GTPGSPGPAGASGNPGTDGIPGAKGSAGAPGIAGAPGFPGPRGPPGPQGATGPLGPKGQT 455
Query: 75 GEPAGLGELGEPAGPGEPEGPGDPAAAPAEAEEQAVEARQEEEQDL-----DGEKG-PSS 128
GEP G GE GEP GP P AP A E+ + E + GE+G P +
Sbjct: 456 GEPGIAGFKGEQGPKGEP-GPAGPQGAPGPAGEEGKRGARGEPGGVGPIGPPGERGAPGN 514
Query: 129 EGPEEEDG 136
G +DG
Sbjct: 515 RGFPGQDG 522
Score = 44.7 bits (104), Expect = 6e-05
Identities = 38/113 (33%), Positives = 46/113 (40%), Gaps = 11/113 (9%)
Query: 30 GAAASPEPARAPPEPAPPAEATGAPAPSRPCAPEPAASPAGPE-EPGEPAGLGELGEPAG 88
GAA P + P PP G P PS P+ A +GP GEP G G P
Sbjct: 900 GAAGRVGPPGSNGNPGPP----GPPGPSGKDGPKGARGDSGPPGRAGEPGLQGPAGPPGE 955
Query: 89 PGEPEGPGDPAAAPAEAEEQAVEARQEEEQDLDGEKG----PSSEGPEEEDGE 137
GEP G P+ A Q + A Q L G++G P GP E G+
Sbjct: 956 KGEP-GDDGPSGAEGPPGPQGL-AGQRGIVGLPGQRGERGFPGLPGPSGEPGK 1006
Score = 43.9 bits (102), Expect = 1e-04
Identities = 35/104 (33%), Positives = 41/104 (39%), Gaps = 13/104 (12%)
Query: 44 PAPPAEATGAPAPSRPCAPEPAASPAGPEEPGEPAGLGELGEPAGPGEPEGPGD--PAAA 101
P P G P P+ AP P P EPGEP G +G PG P PGD A
Sbjct: 202 PMGPMGPRGPPGPAG--APGPQGFQGNPGEPGEPGVSGPMGPRGPPGPPGKPGDDGEAGK 259
Query: 102 PAEAEEQAVEARQEEE-----QDLDGEKG----PSSEGPEEEDG 136
P +A E+ Q L G KG P +G + E G
Sbjct: 260 PGKAGERGPPGPQGARGFPGTPGLPGVKGHRGYPGLDGAKGEAG 303
Score = 42.7 bits (99), Expect = 2e-04
Identities = 40/149 (26%), Positives = 50/149 (33%), Gaps = 42/149 (28%)
Query: 29 RGAAASPEPARAPPEPAPPAEATGAPA-------------------------PSRPCAPE 63
RG P PA PP P PA G P P P +P
Sbjct: 344 RGNDGQPGPA-GPPGPVGPAGGPGFPGAPGAKGEAGPTGARGPEGAQGPRGEPGTPGSPG 402
Query: 64 PAASPAGPEEPGEPAGLGELGEPA-----------GPGEPEGPGDPAAAPAEAEEQAVEA 112
PA + P G P G G P GP P+G P + E + A
Sbjct: 403 PAGASGNPGTDGIPGAKGSAGAPGIAGAPGFPGPRGPPGPQGATGPLGPKGQTGEPGI-A 461
Query: 113 RQEEEQDLDGEKGPS----SEGPEEEDGE 137
+ EQ GE GP+ + GP E+G+
Sbjct: 462 GFKGEQGPKGEPGPAGPQGAPGPAGEEGK 490
Score = 42.4 bits (98), Expect = 3e-04
Identities = 35/116 (30%), Positives = 43/116 (37%), Gaps = 9/116 (7%)
Query: 29 RGAAASPEPARAPPEPAPPAEATGAPAPSRPCAPE------PAASPAGPEEPGEPAGLGE 82
+G +P P EP P G P P P P A G +E A LG
Sbjct: 140 KGEKGAPGPRGRDGEPGTPGNP-GPPGPPGPPGPPGLGGNFAAQMAGGFDEKAGGAQLGV 198
Query: 83 LGEPAGPGEPEGPGDPAAAPAEAEEQAVEARQEEEQDLDGEKGP-SSEGPEEEDGE 137
+ P GP P GP PA AP Q + E + G GP GP + G+
Sbjct: 199 MQGPMGPMGPRGPPGPAGAPGPQGFQG-NPGEPGEPGVSGPMGPRGPPGPPGKPGD 253
Score = 40.8 bits (94), Expect = 8e-04
Identities = 32/105 (30%), Positives = 37/105 (35%), Gaps = 6/105 (5%)
Query: 39 RAPPEPAPPAEATG-APAPSRPCAPEPAASPAGPEEPGEPAGLGELGEPAGPGEPEGPGD 97
R PP P P TG A P R +P P G GE G PG P PG
Sbjct: 1016 RGPPGPVGPPGLTGPAGEPGREGSPGADGPPGRDGAAGVKGDRGETGAVGAPGAPGPPGS 1075
Query: 98 PA-AAPAEAEEQAVEARQEEEQDLDGEKG----PSSEGPEEEDGE 137
P A P + EA + G G +GP + GE
Sbjct: 1076 PGPAGPTGKQGDRGEAGAQGPMGPSGPAGARGIQGPQGPRGDKGE 1120
Score = 40.4 bits (93), Expect = 0.001
Identities = 32/103 (31%), Positives = 39/103 (37%), Gaps = 11/103 (10%)
Query: 38 ARAPPEPAPPAEATGAPAPSRPCAPEPAASPAGPEEPGEPAGLGELGEPAGPGEPEGPGD 97
A PP PA PA G AP P+ P PG P G+ G+ PGE PG
Sbjct: 640 AAGPPGPAGPAGERGEQG-----APGPSGFQGLPGPPGPPGEGGKPGDQGVPGEAGAPG- 693
Query: 98 PAAAPAEAEEQAVEARQEEEQDLDGEKG----PSSEGPEEEDG 136
P E Q L G +G P ++GP+ G
Sbjct: 694 -LVGPRGERGFPGERGSPGAQGLQGPRGLPGTPGTDGPKGASG 735
Score = 39.3 bits (90), Expect = 0.002
Identities = 42/126 (33%), Positives = 49/126 (38%), Gaps = 19/126 (15%)
Query: 29 RGAA--ASPEPARAP-----PEPAPPAEA----TGAPAPSRPCAPEPAASPAGPEEPGEP 77
RGAA A P+ R PE AP + TG P P GP P
Sbjct: 755 RGAAGIAGPKGDRGDVGEKGPEGAPGKDGGRGLTGPIGPPGPAGANGEKGEVGPPGPAGS 814
Query: 78 AGL----GELGE--PAGPGEPEGPGDPAAAPAEAEEQAVEARQEEEQDLDGEKGPS-SEG 130
AG GE GE P GP GP P EQ EA Q+ + G +GPS + G
Sbjct: 815 AGARGAPGERGETGPPGPAGFAGPPGADGQPGAKGEQG-EAGQKGDAGAPGPQGPSGAPG 873
Query: 131 PEEEDG 136
P+ G
Sbjct: 874 PQGPTG 879
Score = 39.3 bits (90), Expect = 0.002
Identities = 33/124 (26%), Positives = 40/124 (32%), Gaps = 17/124 (13%)
Query: 30 GAAASPEPARAPPEPAPPAEATGAPAPSRPCAPEPAASPAGPEEPGEPAGLGELGEPAGP 89
G A P +P PP A +P P PG P G G+
Sbjct: 1029 GPAGEPGREGSPGADGPPGRDGAAGVKGDRGETGAVGAPGAPGPPGSPGPAGPTGKQGDR 1088
Query: 90 GE-----PEGPGDPAAA-----PAEAEEQAVEARQEEEQDLDGEKG-------PSSEGPE 132
GE P GP PA A P EA + E+ L G +G P GP
Sbjct: 1089 GEAGAQGPMGPSGPAGARGIQGPQGPRGDKGEAGEPGERGLKGHRGFTGLQGLPGPPGPS 1148
Query: 133 EEDG 136
+ G
Sbjct: 1149 GDQG 1152
Score = 39.3 bits (90), Expect = 0.002
Identities = 25/68 (36%), Positives = 27/68 (39%), Gaps = 11/68 (16%)
Query: 33 ASPEPARAPPEPAPPAE---ATGAPAPSRPCAPEPAASPAGPE-EPGEPAGLGELGEPAG 88
A P R PP P P+ A G P P P P + GP PG P P G
Sbjct: 1157 AGPSGPRGPPGPVGPSGKDGANGIPGPIGPPGPRGRSGETGPAGPPGNPG-------PPG 1209
Query: 89 PGEPEGPG 96
P P GPG
Sbjct: 1210 PPGPPGPG 1217
Score = 38.9 bits (89), Expect = 0.003
Identities = 43/144 (29%), Positives = 53/144 (36%), Gaps = 50/144 (34%)
Query: 29 RGAAASPEPARAPPEPAP-----PAEATGAPAPSR---------------------PCAP 62
+G+A +P A AP P P P ATG P P P
Sbjct: 419 KGSAGAPGIAGAPGFPGPRGPPGPQGATGPLGPKGQTGEPGIAGFKGEQGPKGEPGPAGP 478
Query: 63 EPAASPAGPEEP----GEPAGLGELG---EPAGPGEPEGPG-DPAAAPAEAEEQAVEARQ 114
+ A PAG E GEP G+G +G E PG PG D A P A
Sbjct: 479 QGAPGPAGEEGKRGARGEPGGVGPIGPPGERGAPGNRGFPGQDGLAGPKGA--------- 529
Query: 115 EEEQDLDGEKGPSS-EGPEEEDGE 137
GE+GPS GP+ +G+
Sbjct: 530 ------PGERGPSGLAGPKGANGD 547
Score = 38.5 bits (88), Expect = 0.004
Identities = 30/101 (29%), Positives = 37/101 (36%), Gaps = 19/101 (18%)
Query: 41 PPEPAPPAEATGAPAPSRPCAPEPAASPAG-------PEEPGEPAGLGELGE--PAGPGE 91
PP P+ A+G PS P P P+G P G P G GE PAGP
Sbjct: 1144 PPGPSGDQGASGPAGPSGPRGPPGPVGPSGKDGANGIPGPIGPPGPRGRSGETGPAGPPG 1203
Query: 92 PEGPGDPAAAPAEAEEQAVEARQEEEQDLDGEKGPSSEGPE 132
GP P P + + A GP +GP+
Sbjct: 1204 NPGPPGPPGPPGPGIDMSAFA----------GLGPREKGPD 1234
Score = 37.0 bits (84), Expect = 0.012
Identities = 41/122 (33%), Positives = 46/122 (37%), Gaps = 23/122 (18%)
Query: 35 PEPARAPPEPAPPAEATGAPAPS----RPCAP-EPAAS-PAGPE-EPGEPAGLGELGEPA 87
P R PP PA GAP P P P EP S P GP PG P G+ GE
Sbjct: 205 PMGPRGPPGPA------GAPGPQGFQGNPGEPGEPGVSGPMGPRGPPGPPGKPGDDGEAG 258
Query: 88 GPGE-----PEGPGDPAAAPAEAEEQAVEARQEEEQDLDGEKG----PSSEGPEEEDGEG 138
PG+ P GP P V+ + LDG KG P +G GE
Sbjct: 259 KPGKAGERGPPGPQGARGFPGTPGLPGVKGHR-GYPGLDGAKGEAGAPGVKGESGSPGEN 317
Query: 139 FS 140
S
Sbjct: 318 GS 319
Score = 37.0 bits (84), Expect = 0.012
Identities = 22/70 (31%), Positives = 24/70 (34%), Gaps = 13/70 (18%)
Query: 42 PEPAPPAEATGAPAPSRPCAPEPAASPAGPE-------------EPGEPAGLGELGEPAG 88
P P P+ GA P+ P P P GP PG GE G
Sbjct: 1142 PGPPGPSGDQGASGPAGPSGPRGPPGPVGPSGKDGANGIPGPIGPPGPRGRSGETGPAGP 1201
Query: 89 PGEPEGPGDP 98
PG P PG P
Sbjct: 1202 PGNPGPPGPP 1211
Score = 35.8 bits (81), Expect = 0.026
Identities = 21/69 (30%), Positives = 24/69 (34%), Gaps = 1/69 (1%)
Query: 31 AAASPEPARAPPEPAPPAEATGAPAPSRPCAPEPAASPAGPE-EPGEPAGLGELGEPAGP 89
A+ P P EP + G P P P P G + GE G G P
Sbjct: 96 ASGQPGPKGQKGEPGDIKDIVGPKGPPGPQGPAGEQGPRGDRGDKGEKGAPGPRGRDGEP 155
Query: 90 GEPEGPGDP 98
G P PG P
Sbjct: 156 GTPGNPGPP 164
Score = 35.4 bits (80), Expect = 0.034
Identities = 35/112 (31%), Positives = 40/112 (35%), Gaps = 14/112 (12%)
Query: 30 GAAASPEPARAPPEPAPPAEA--TGAPAPSRPCAPEPAASPAGPEEPGEPAGLGELGEPA 87
G P P A EP E GAP + AGP P PAG E GE
Sbjct: 600 GVMGFPGPKGANGEPGKAGEKGLPGAPGLRGLPGKDGETGAAGPPGPAGPAG--ERGEQG 657
Query: 88 GPGEP--EGPGDPAAAPAEAEEQAVEARQEEEQDLDGEKG-PSSEGPEEEDG 136
PG +G P P E + +Q + GE G P GP E G
Sbjct: 658 APGPSGFQGLPGPPGPPGEGGKPG-------DQGVPGEAGAPGLVGPRGERG 702
Score = 34.7 bits (78), Expect = 0.058
Identities = 34/143 (23%), Positives = 45/143 (31%), Gaps = 28/143 (19%)
Query: 29 RGAAASPEPARAPPEPAPPAEATGAPAPSRPCAPEPAASPAGPEEPGEPAGLGELGE--- 85
RG +P P+ P PP P P A +P GE GE G
Sbjct: 653 RGEQGAPGPSGFQGLPGPPGPPGEGGKPGDQGVPGEAGAPGLVGPRGERGFPGERGSPGA 712
Query: 86 -----------------------PAGPGEPEGPGDPAAAPAEAEEQAVEARQEEEQDLDG 122
PAGP +GP P E + + + D+ G
Sbjct: 713 QGLQGPRGLPGTPGTDGPKGASGPAGPPGAQGPPGLQGMPGERGAAGIAGPKGDRGDV-G 771
Query: 123 EKGPSSEGPEEEDGEGFSFKYSP 145
EKGP P ++ G G + P
Sbjct: 772 EKGPEG-APGKDGGRGLTGPIGP 793
Score = 34.3 bits (77), Expect = 0.075
Identities = 34/114 (29%), Positives = 38/114 (33%), Gaps = 21/114 (18%)
Query: 45 APPAEATGAPAPSRPCAPEPA-ASPAGPEEPGEPAGLGELGEPA------------GPGE 91
A P A G PS P+ A P P EPG P G G P PGE
Sbjct: 524 AGPKGAPGERGPSGLAGPKGANGDPGRPGEPGLPGARGLTGRPGDAGPQGKVGPSGAPGE 583
Query: 92 PEGPGDPAAAPAEAEEQAV----EARQEEEQDLDGEKG----PSSEGPEEEDGE 137
PG P A + + E GEKG P G +DGE
Sbjct: 584 DGRPGPPGPQGARGQPGVMGFPGPKGANGEPGKAGEKGLPGAPGLRGLPGKDGE 637
Score = 33.9 bits (76), Expect = 0.098
Identities = 37/122 (30%), Positives = 41/122 (33%), Gaps = 17/122 (13%)
Query: 30 GAAASPEPARAPPEPAPPAEATGAPAPSRPCAPE-PAASPAGPEEPGEPAGLGELGE--- 85
G A +P P P P E G P P P P P E G+P GE G
Sbjct: 213 GPAGAPGPQGFQGNPGEPGEP-GVSGPMGPRGPPGPPGKPGDDGEAGKPGKAGERGPPGP 271
Query: 86 ------PAGPGEPEGPGD---PAAAPAEAEEQAVEARQEEEQDLDGEKG-PSSEGPEEED 135
P PG P G P A+ E A + E GE G P GP
Sbjct: 272 QGARGFPGTPGLPGVKGHRGYPGLDGAKGEAGAPGVKGESGS--PGENGSPGPMGPRGLP 329
Query: 136 GE 137
GE
Sbjct: 330 GE 331
Score = 33.9 bits (76), Expect = 0.098
Identities = 40/135 (29%), Positives = 48/135 (35%), Gaps = 41/135 (30%)
Query: 28 RRGAAASPEPARAPPEPAP-----------------PAEATGAP-APSRPCAPEPAASPA 69
++G A +P P P P P ATG P A R P +P
Sbjct: 856 QKGDAGAPGPQGPSGAPGPQGPTGVTGPKGARGAQGPPGATGFPGAAGRVGPPGSNGNPG 915
Query: 70 GPEEPGEPAG-------LGELGEPAGPGEPEGPGDPAAAPAEAEEQAVEARQEEEQDLDG 122
P PG P+G G+ G P GEP G PA P E E G
Sbjct: 916 PPGPPG-PSGKDGPKGARGDSGPPGRAGEP-GLQGPAGPPGEKGE-------------PG 960
Query: 123 EKGPS-SEGPEEEDG 136
+ GPS +EGP G
Sbjct: 961 DDGPSGAEGPPGPQG 975
Score = 33.9 bits (76), Expect = 0.098
Identities = 18/48 (37%), Positives = 22/48 (45%), Gaps = 1/48 (2%)
Query: 52 GAPAPSRPCAPEPAASPAGPEEP-GEPAGLGELGEPAGPGEPEGPGDP 98
G P P P + A+ PAGP P G P +G G+ G P G P
Sbjct: 1140 GLPGPPGPSGDQGASGPAGPSGPRGPPGPVGPSGKDGANGIPGPIGPP 1187
Score = 33.1 bits (74), Expect = 0.17
Identities = 26/83 (31%), Positives = 36/83 (43%), Gaps = 19/83 (22%)
Query: 59 PCAPEPAASPAGPEEP----GEPAGLGELGEPAGPGEPEGPGDPAAAPAEAEEQAVEARQ 114
P P A+ +G P GEP + ++ P GP P+GP A EQ +
Sbjct: 87 PICPTDLATASGQPGPKGQKGEPGDIKDIVGPKGPPGPQGP---------AGEQGPRGDR 137
Query: 115 EEEQDLDGEKGPSSEGPEEEDGE 137
++ GEKG + GP DGE
Sbjct: 138 GDK----GEKG--APGPRGRDGE 154
Score = 32.7 bits (73), Expect = 0.22
Identities = 36/118 (30%), Positives = 45/118 (38%), Gaps = 14/118 (11%)
Query: 30 GAAASPEPARAPPEPAPPAEATGAPAPSRPCAP-----EPAAS-PAGPEEPGEPAGL--- 80
G + P A + PP A G P P P EP P+G E P P GL
Sbjct: 921 GPSGKDGPKGARGDSGPPGRA-GEPGLQGPAGPPGEKGEPGDDGPSGAEGPPGPQGLAGQ 979
Query: 81 -GELGEPAGPGEPEGPGDPAAAPAEAEEQAVEARQEEEQDLDGEKGPSS-EGPEEEDG 136
G +G P GE PG P + ++ A A ++ G GP GP E G
Sbjct: 980 RGIVGLPGQRGERGFPGLPGPSGEPGKQGAPGA--SGDRGPPGPVGPPGLTGPAGEPG 1035
Score = 32.3 bits (72), Expect = 0.29
Identities = 34/122 (27%), Positives = 40/122 (32%), Gaps = 14/122 (11%)
Query: 29 RGAAASPEPARAPPEPAPPAEATGAPAPSRPCAPEPAASPAGPEEPGEPAGLGELGEPAG 88
+G P A E P + +P +P P P E G G G
Sbjct: 287 KGHRGYPGLDGAKGEAGAPGVKGESGSPGENGSPGPMGPRGLPGERGRTGPAGAAGARGN 346
Query: 89 PGEPE------------GPGDPAAAPAEAEEQAVEAR-QEEEQDLDGEKG-PSSEGPEEE 134
G+P GPG P A A+ E AR E Q GE G P S GP
Sbjct: 347 DGQPGPAGPPGPVGPAGGPGFPGAPGAKGEAGPTGARGPEGAQGPRGEPGTPGSPGPAGA 406
Query: 135 DG 136
G
Sbjct: 407 SG 408
Score = 32.0 bits (71), Expect = 0.37
Identities = 43/155 (27%), Positives = 48/155 (30%), Gaps = 47/155 (30%)
Query: 30 GAAASPEPARA--------PPEPAPPAEATGAPAPSRPCAPEPAASPAGPE-EPGEPAGL 80
G P PA A PP PA A A GAP P A AGP G+P
Sbjct: 789 GPIGPPGPAGANGEKGEVGPPGPAGSAGARGAPGERGETGPPGPAGFAGPPGADGQPGAK 848
Query: 81 GELGE--------------PAGPGEPEGP-------------------GDPAAA----PA 103
GE GE P+G P+GP G P AA P
Sbjct: 849 GEQGEAGQKGDAGAPGPQGPSGAPGPQGPTGVTGPKGARGAQGPPGATGFPGAAGRVGPP 908
Query: 104 EAEEQAVEARQEEEQDLDGEKGPSSE-GPEEEDGE 137
+ DG KG + GP GE
Sbjct: 909 GSNGNPGPPGPPGPSGKDGPKGARGDSGPPGRAGE 943
Score = 31.6 bits (70), Expect = 0.49
Identities = 36/122 (29%), Positives = 41/122 (33%), Gaps = 9/122 (7%)
Query: 30 GAAASPEPA--RAPPEPAPPAEATGAPA-PSRPCAPEPAASPAGPEEPGEPAGLGELGEP 86
G A P A R PP P A G P P P P GE G GE
Sbjct: 255 GEAGKPGKAGERGPPGPQG---ARGFPGTPGLPGVKGHRGYPGLDGAKGEAGAPGVKGES 311
Query: 87 AGPGEPEGPG--DPAAAPAEAEEQAVEARQEEEQDLDGEKGPSSEGPEEEDGEGFSFKYS 144
PGE PG P P E + A + DG+ GP+ G F +
Sbjct: 312 GSPGENGSPGPMGPRGLPGE-RGRTGPAGAAGARGNDGQPGPAGPPGPVGPAGGPGFPGA 370
Query: 145 PG 146
PG
Sbjct: 371 PG 372
Score = 31.2 bits (69), Expect = 0.64
Identities = 30/109 (27%), Positives = 36/109 (33%), Gaps = 5/109 (4%)
Query: 33 ASPEPARAPPEPAPPAEATGAPAPSRPCAPEPAASPAGPE-EPGEPAGLGELGE--PAGP 89
A P A+ PP GA + P GPE PG+ G G G P GP
Sbjct: 737 AGPPGAQGPPGLQGMPGERGAAGIAGPKGDRGDVGEKGPEGAPGKDGGRGLTGPIGPPGP 796
Query: 90 GEPEGPGDPAAAPAEAEEQAVEARQEEEQDLDGEKGPSS-EGPEEEDGE 137
G P A E + G GP+ GP DG+
Sbjct: 797 AGANGEKGEVGPPGPAGSAGARGAPGERGE-TGPPGPAGFAGPPGADGQ 844
Score = 30.0 bits (66), Expect = 1.4
Identities = 34/121 (28%), Positives = 39/121 (32%), Gaps = 13/121 (10%)
Query: 29 RGAAASPEPARAPPEPAPPAEATGAPAPSRPCAPEPAASPAGPEE-PGEPAGLGELGEPA 87
RG P A P P+ A G P P+ A G PG GE G+
Sbjct: 560 RGLTGRPGDA-GPQGKVGPSGAPGEDGRPGPPGPQGARGQPGVMGFPGPKGANGEPGKAG 618
Query: 88 GPGEPEGPG-------DPAAAPAEAEEQAVEARQEEEQDLDGEKG----PSSEGPEEEDG 136
G P PG D A A A + EQ G G P GP E G
Sbjct: 619 EKGLPGAPGLRGLPGKDGETGAAGPPGPAGPAGERGEQGAPGPSGFQGLPGPPGPPGEGG 678
Query: 137 E 137
+
Sbjct: 679 K 679
Score = 29.6 bits (65), Expect = 1.9
Identities = 21/59 (35%), Positives = 22/59 (37%), Gaps = 8/59 (13%)
Query: 41 PPEPAPPAEATGAPAPSRPCAPEPAASPAGPEEPGEPAGL-GELGEPAGPGEPEGPGDP 98
P P P E AP A+ GP P P GL G GEP G P G P
Sbjct: 995 PGLPGPSGEPGKQGAPG-------ASGDRGPPGPVGPPGLTGPAGEPGREGSPGADGPP 1046
Score = 29.6 bits (65), Expect = 1.9
Identities = 20/72 (27%), Positives = 21/72 (29%), Gaps = 25/72 (34%)
Query: 52 GAPAPSRPCAPEPAASPAGPEEPGEPAG-------------------------LGELGEP 86
G P PS A P+GP P P G G G P
Sbjct: 1143 GPPGPSGDQGASGPAGPSGPRGPPGPVGPSGKDGANGIPGPIGPPGPRGRSGETGPAGPP 1202
Query: 87 AGPGEPEGPGDP 98
PG P PG P
Sbjct: 1203 GNPGPPGPPGPP 1214
Score = 29.3 bits (64), Expect = 2.4
Identities = 35/128 (27%), Positives = 41/128 (32%), Gaps = 37/128 (28%)
Query: 28 RRGAAASPE---PARAPPEPAPPAEATGAPAPSRPCAPEPAASPAGPE-------EPGEP 77
+RGA P P P E P G P P+ A GP G+P
Sbjct: 490 KRGARGEPGGVGPIGPPGERGAPGNR-GFPGQDGLAGPKGAPGERGPSGLAGPKGANGDP 548
Query: 78 AGLGELGEPAGPGEPEGPGD--------PAAAPAEAEEQAVEARQEEEQDLDGEKGPSSE 129
GE G P G PGD P+ AP E DG GP
Sbjct: 549 GRPGEPGLPGARGLTGRPGDAGPQGKVGPSGAPGE----------------DGRPGP--P 590
Query: 130 GPEEEDGE 137
GP+ G+
Sbjct: 591 GPQGARGQ 598
Score = 29.3 bits (64), Expect = 2.4
Identities = 26/89 (29%), Positives = 32/89 (35%), Gaps = 11/89 (12%)
Query: 52 GAPAPSRPCAPEPAASPAGPEEPGEPAGLGELGEPAGPGEPEGPGDPAAAPAEAEEQAVE 111
G P PS + A +G P P G L PA GEP G P A + A
Sbjct: 996 GLPGPSGEPGKQGAPGASGDRGPPGPVGPPGLTGPA--GEPGREGSPGADGPPGRDGAAG 1053
Query: 112 ARQEEEQDLDGEKG----PSSEGPEEEDG 136
+ + GE G P + GP G
Sbjct: 1054 VKGDR-----GETGAVGAPGAPGPPGSPG 1077
Score = 29.3 bits (64), Expect = 2.4
Identities = 29/97 (29%), Positives = 33/97 (34%), Gaps = 11/97 (11%)
Query: 42 PEPAPPAEATGAPAPSRPCAPEPAASPAGPEEPGEPAGLGELGEPAGPGEPEGPGDPAAA 101
P P+ GAP S P P GP PG GE G PG PG AA
Sbjct: 998 PGPSGEPGKQGAPGASGDRGPP---GPVGP--PGLTGPAGEPGREGSPGADGPPGRDGAA 1052
Query: 102 PAEAEEQAVEARQEEEQDLDGEKG-PSSEGPEEEDGE 137
+ + A G G P S GP G+
Sbjct: 1053 GVKGDRGETGA-----VGAPGAPGPPGSPGPAGPTGK 1084
>gi|111118974 collagen, type II, alpha 1 isoform 2 precursor [Homo
sapiens]
Length = 1418
Score = 51.2 bits (121), Expect = 6e-07
Identities = 42/128 (32%), Positives = 51/128 (39%), Gaps = 22/128 (17%)
Query: 30 GAAASPEPARAPPEPAPP--------------AEATGAPAPSRPCAPEPAASPAGPE-EP 74
G SP PA A P A A G P P P P+ A P GP+ +
Sbjct: 327 GTPGSPGPAGASGNPGTDGIPGAKGSAGAPGIAGAPGFPGPRGPPGPQGATGPLGPKGQT 386
Query: 75 GEPAGLGELGEPAGPGEPEGPGDPAAAPAEAEEQAVEARQEEEQDL-----DGEKG-PSS 128
GEP G GE GEP GP P AP A E+ + E + GE+G P +
Sbjct: 387 GEPGIAGFKGEQGPKGEP-GPAGPQGAPGPAGEEGKRGARGEPGGVGPIGPPGERGAPGN 445
Query: 129 EGPEEEDG 136
G +DG
Sbjct: 446 RGFPGQDG 453
Score = 44.7 bits (104), Expect = 6e-05
Identities = 38/113 (33%), Positives = 46/113 (40%), Gaps = 11/113 (9%)
Query: 30 GAAASPEPARAPPEPAPPAEATGAPAPSRPCAPEPAASPAGPE-EPGEPAGLGELGEPAG 88
GAA P + P PP G P PS P+ A +GP GEP G G P
Sbjct: 831 GAAGRVGPPGSNGNPGPP----GPPGPSGKDGPKGARGDSGPPGRAGEPGLQGPAGPPGE 886
Query: 89 PGEPEGPGDPAAAPAEAEEQAVEARQEEEQDLDGEKG----PSSEGPEEEDGE 137
GEP G P+ A Q + A Q L G++G P GP E G+
Sbjct: 887 KGEP-GDDGPSGAEGPPGPQGL-AGQRGIVGLPGQRGERGFPGLPGPSGEPGK 937
Score = 43.9 bits (102), Expect = 1e-04
Identities = 35/104 (33%), Positives = 41/104 (39%), Gaps = 13/104 (12%)
Query: 44 PAPPAEATGAPAPSRPCAPEPAASPAGPEEPGEPAGLGELGEPAGPGEPEGPGD--PAAA 101
P P G P P+ AP P P EPGEP G +G PG P PGD A
Sbjct: 133 PMGPMGPRGPPGPAG--APGPQGFQGNPGEPGEPGVSGPMGPRGPPGPPGKPGDDGEAGK 190
Query: 102 PAEAEEQAVEARQEEE-----QDLDGEKG----PSSEGPEEEDG 136
P +A E+ Q L G KG P +G + E G
Sbjct: 191 PGKAGERGPPGPQGARGFPGTPGLPGVKGHRGYPGLDGAKGEAG 234
Score = 42.7 bits (99), Expect = 2e-04
Identities = 40/149 (26%), Positives = 50/149 (33%), Gaps = 42/149 (28%)
Query: 29 RGAAASPEPARAPPEPAPPAEATGAPA-------------------------PSRPCAPE 63
RG P PA PP P PA G P P P +P
Sbjct: 275 RGNDGQPGPA-GPPGPVGPAGGPGFPGAPGAKGEAGPTGARGPEGAQGPRGEPGTPGSPG 333
Query: 64 PAASPAGPEEPGEPAGLGELGEPA-----------GPGEPEGPGDPAAAPAEAEEQAVEA 112
PA + P G P G G P GP P+G P + E + A
Sbjct: 334 PAGASGNPGTDGIPGAKGSAGAPGIAGAPGFPGPRGPPGPQGATGPLGPKGQTGEPGI-A 392
Query: 113 RQEEEQDLDGEKGPS----SEGPEEEDGE 137
+ EQ GE GP+ + GP E+G+
Sbjct: 393 GFKGEQGPKGEPGPAGPQGAPGPAGEEGK 421
Score = 42.4 bits (98), Expect = 3e-04
Identities = 35/116 (30%), Positives = 43/116 (37%), Gaps = 9/116 (7%)
Query: 29 RGAAASPEPARAPPEPAPPAEATGAPAPSRPCAPE------PAASPAGPEEPGEPAGLGE 82
+G +P P EP P G P P P P A G +E A LG
Sbjct: 71 KGEKGAPGPRGRDGEPGTPGNP-GPPGPPGPPGPPGLGGNFAAQMAGGFDEKAGGAQLGV 129
Query: 83 LGEPAGPGEPEGPGDPAAAPAEAEEQAVEARQEEEQDLDGEKGP-SSEGPEEEDGE 137
+ P GP P GP PA AP Q + E + G GP GP + G+
Sbjct: 130 MQGPMGPMGPRGPPGPAGAPGPQGFQG-NPGEPGEPGVSGPMGPRGPPGPPGKPGD 184
Score = 42.0 bits (97), Expect = 4e-04
Identities = 30/92 (32%), Positives = 34/92 (36%), Gaps = 5/92 (5%)
Query: 12 PALATALALLLAWLLVRRGA-AASPEPARAPPEPAPPAEATGAPAPSRPCAPEPAASPAG 70
P L LL+A +L +G P P EP + G P P P P G
Sbjct: 7 PQTLVLLTLLVAAVLRCQGQDVRQPGPKGQKGEPGDIKDIVGPKGPPGPQGPAGEQGPRG 66
Query: 71 PE----EPGEPAGLGELGEPAGPGEPEGPGDP 98
E G P G GEP PG P PG P
Sbjct: 67 DRGDKGEKGAPGPRGRDGEPGTPGNPGPPGPP 98
Score = 40.8 bits (94), Expect = 8e-04
Identities = 32/105 (30%), Positives = 37/105 (35%), Gaps = 6/105 (5%)
Query: 39 RAPPEPAPPAEATG-APAPSRPCAPEPAASPAGPEEPGEPAGLGELGEPAGPGEPEGPGD 97
R PP P P TG A P R +P P G GE G PG P PG
Sbjct: 947 RGPPGPVGPPGLTGPAGEPGREGSPGADGPPGRDGAAGVKGDRGETGAVGAPGAPGPPGS 1006
Query: 98 PA-AAPAEAEEQAVEARQEEEQDLDGEKG----PSSEGPEEEDGE 137
P A P + EA + G G +GP + GE
Sbjct: 1007 PGPAGPTGKQGDRGEAGAQGPMGPSGPAGARGIQGPQGPRGDKGE 1051
Score = 40.4 bits (93), Expect = 0.001
Identities = 32/103 (31%), Positives = 39/103 (37%), Gaps = 11/103 (10%)
Query: 38 ARAPPEPAPPAEATGAPAPSRPCAPEPAASPAGPEEPGEPAGLGELGEPAGPGEPEGPGD 97
A PP PA PA G AP P+ P PG P G+ G+ PGE PG
Sbjct: 571 AAGPPGPAGPAGERGEQG-----APGPSGFQGLPGPPGPPGEGGKPGDQGVPGEAGAPG- 624
Query: 98 PAAAPAEAEEQAVEARQEEEQDLDGEKG----PSSEGPEEEDG 136
P E Q L G +G P ++GP+ G
Sbjct: 625 -LVGPRGERGFPGERGSPGAQGLQGPRGLPGTPGTDGPKGASG 666
Score = 39.3 bits (90), Expect = 0.002
Identities = 42/126 (33%), Positives = 49/126 (38%), Gaps = 19/126 (15%)
Query: 29 RGAA--ASPEPARAP-----PEPAPPAEA----TGAPAPSRPCAPEPAASPAGPEEPGEP 77
RGAA A P+ R PE AP + TG P P GP P
Sbjct: 686 RGAAGIAGPKGDRGDVGEKGPEGAPGKDGGRGLTGPIGPPGPAGANGEKGEVGPPGPAGS 745
Query: 78 AGL----GELGE--PAGPGEPEGPGDPAAAPAEAEEQAVEARQEEEQDLDGEKGPS-SEG 130
AG GE GE P GP GP P EQ EA Q+ + G +GPS + G
Sbjct: 746 AGARGAPGERGETGPPGPAGFAGPPGADGQPGAKGEQG-EAGQKGDAGAPGPQGPSGAPG 804
Query: 131 PEEEDG 136
P+ G
Sbjct: 805 PQGPTG 810
Score = 39.3 bits (90), Expect = 0.002
Identities = 33/124 (26%), Positives = 40/124 (32%), Gaps = 17/124 (13%)
Query: 30 GAAASPEPARAPPEPAPPAEATGAPAPSRPCAPEPAASPAGPEEPGEPAGLGELGEPAGP 89
G A P +P PP A +P P PG P G G+
Sbjct: 960 GPAGEPGREGSPGADGPPGRDGAAGVKGDRGETGAVGAPGAPGPPGSPGPAGPTGKQGDR 1019
Query: 90 GE-----PEGPGDPAAA-----PAEAEEQAVEARQEEEQDLDGEKG-------PSSEGPE 132
GE P GP PA A P EA + E+ L G +G P GP
Sbjct: 1020 GEAGAQGPMGPSGPAGARGIQGPQGPRGDKGEAGEPGERGLKGHRGFTGLQGLPGPPGPS 1079
Query: 133 EEDG 136
+ G
Sbjct: 1080 GDQG 1083
Score = 39.3 bits (90), Expect = 0.002
Identities = 25/68 (36%), Positives = 27/68 (39%), Gaps = 11/68 (16%)
Query: 33 ASPEPARAPPEPAPPA---EATGAPAPSRPCAPEPAASPAGPE-EPGEPAGLGELGEPAG 88
A P R PP P P+ A G P P P P + GP PG P P G
Sbjct: 1088 AGPSGPRGPPGPVGPSGKDGANGIPGPIGPPGPRGRSGETGPAGPPGNPG-------PPG 1140
Query: 89 PGEPEGPG 96
P P GPG
Sbjct: 1141 PPGPPGPG 1148
Score = 38.9 bits (89), Expect = 0.003
Identities = 43/144 (29%), Positives = 53/144 (36%), Gaps = 50/144 (34%)
Query: 29 RGAAASPEPARAPPEPAP-----PAEATGAPAPSR---------------------PCAP 62
+G+A +P A AP P P P ATG P P P
Sbjct: 350 KGSAGAPGIAGAPGFPGPRGPPGPQGATGPLGPKGQTGEPGIAGFKGEQGPKGEPGPAGP 409
Query: 63 EPAASPAGPEEP----GEPAGLGELG---EPAGPGEPEGPG-DPAAAPAEAEEQAVEARQ 114
+ A PAG E GEP G+G +G E PG PG D A P A
Sbjct: 410 QGAPGPAGEEGKRGARGEPGGVGPIGPPGERGAPGNRGFPGQDGLAGPKGA--------- 460
Query: 115 EEEQDLDGEKGPSS-EGPEEEDGE 137
GE+GPS GP+ +G+
Sbjct: 461 ------PGERGPSGLAGPKGANGD 478
Score = 38.5 bits (88), Expect = 0.004
Identities = 30/101 (29%), Positives = 37/101 (36%), Gaps = 19/101 (18%)
Query: 41 PPEPAPPAEATGAPAPSRPCAPEPAASPAG-------PEEPGEPAGLGELGE--PAGPGE 91
PP P+ A+G PS P P P+G P G P G GE PAGP
Sbjct: 1075 PPGPSGDQGASGPAGPSGPRGPPGPVGPSGKDGANGIPGPIGPPGPRGRSGETGPAGPPG 1134
Query: 92 PEGPGDPAAAPAEAEEQAVEARQEEEQDLDGEKGPSSEGPE 132
GP P P + + A GP +GP+
Sbjct: 1135 NPGPPGPPGPPGPGIDMSAFA----------GLGPREKGPD 1165
Score = 37.0 bits (84), Expect = 0.012
Identities = 41/122 (33%), Positives = 46/122 (37%), Gaps = 23/122 (18%)
Query: 35 PEPARAPPEPAPPAEATGAPAPS----RPCAP-EPAAS-PAGPE-EPGEPAGLGELGEPA 87
P R PP PA GAP P P P EP S P GP PG P G+ GE
Sbjct: 136 PMGPRGPPGPA------GAPGPQGFQGNPGEPGEPGVSGPMGPRGPPGPPGKPGDDGEAG 189
Query: 88 GPGE-----PEGPGDPAAAPAEAEEQAVEARQEEEQDLDGEKG----PSSEGPEEEDGEG 138
PG+ P GP P V+ + LDG KG P +G GE
Sbjct: 190 KPGKAGERGPPGPQGARGFPGTPGLPGVKGHR-GYPGLDGAKGEAGAPGVKGESGSPGEN 248
Query: 139 FS 140
S
Sbjct: 249 GS 250
Score = 37.0 bits (84), Expect = 0.012
Identities = 22/70 (31%), Positives = 24/70 (34%), Gaps = 13/70 (18%)
Query: 42 PEPAPPAEATGAPAPSRPCAPEPAASPAGPE-------------EPGEPAGLGELGEPAG 88
P P P+ GA P+ P P P GP PG GE G
Sbjct: 1073 PGPPGPSGDQGASGPAGPSGPRGPPGPVGPSGKDGANGIPGPIGPPGPRGRSGETGPAGP 1132
Query: 89 PGEPEGPGDP 98
PG P PG P
Sbjct: 1133 PGNPGPPGPP 1142
Score = 35.4 bits (80), Expect = 0.034
Identities = 35/112 (31%), Positives = 40/112 (35%), Gaps = 14/112 (12%)
Query: 30 GAAASPEPARAPPEPAPPAEA--TGAPAPSRPCAPEPAASPAGPEEPGEPAGLGELGEPA 87
G P P A EP E GAP + AGP P PAG E GE
Sbjct: 531 GVMGFPGPKGANGEPGKAGEKGLPGAPGLRGLPGKDGETGAAGPPGPAGPAG--ERGEQG 588
Query: 88 GPGEP--EGPGDPAAAPAEAEEQAVEARQEEEQDLDGEKG-PSSEGPEEEDG 136
PG +G P P E + +Q + GE G P GP E G
Sbjct: 589 APGPSGFQGLPGPPGPPGEGGKPG-------DQGVPGEAGAPGLVGPRGERG 633
Score = 34.7 bits (78), Expect = 0.058
Identities = 34/143 (23%), Positives = 45/143 (31%), Gaps = 28/143 (19%)
Query: 29 RGAAASPEPARAPPEPAPPAEATGAPAPSRPCAPEPAASPAGPEEPGEPAGLGELGE--- 85
RG +P P+ P PP P P A +P GE GE G
Sbjct: 584 RGEQGAPGPSGFQGLPGPPGPPGEGGKPGDQGVPGEAGAPGLVGPRGERGFPGERGSPGA 643
Query: 86 -----------------------PAGPGEPEGPGDPAAAPAEAEEQAVEARQEEEQDLDG 122
PAGP +GP P E + + + D+ G
Sbjct: 644 QGLQGPRGLPGTPGTDGPKGASGPAGPPGAQGPPGLQGMPGERGAAGIAGPKGDRGDV-G 702
Query: 123 EKGPSSEGPEEEDGEGFSFKYSP 145
EKGP P ++ G G + P
Sbjct: 703 EKGPEG-APGKDGGRGLTGPIGP 724
Score = 34.3 bits (77), Expect = 0.075
Identities = 34/114 (29%), Positives = 38/114 (33%), Gaps = 21/114 (18%)
Query: 45 APPAEATGAPAPSRPCAPEPA-ASPAGPEEPGEPAGLGELGEPA------------GPGE 91
A P A G PS P+ A P P EPG P G G P PGE
Sbjct: 455 AGPKGAPGERGPSGLAGPKGANGDPGRPGEPGLPGARGLTGRPGDAGPQGKVGPSGAPGE 514
Query: 92 PEGPGDPAAAPAEAEEQAV----EARQEEEQDLDGEKG----PSSEGPEEEDGE 137
PG P A + + E GEKG P G +DGE
Sbjct: 515 DGRPGPPGPQGARGQPGVMGFPGPKGANGEPGKAGEKGLPGAPGLRGLPGKDGE 568
Score = 33.9 bits (76), Expect = 0.098
Identities = 37/122 (30%), Positives = 41/122 (33%), Gaps = 17/122 (13%)
Query: 30 GAAASPEPARAPPEPAPPAEATGAPAPSRPCAPE-PAASPAGPEEPGEPAGLGELGE--- 85
G A +P P P P E G P P P P P E G+P GE G
Sbjct: 144 GPAGAPGPQGFQGNPGEPGEP-GVSGPMGPRGPPGPPGKPGDDGEAGKPGKAGERGPPGP 202
Query: 86 ------PAGPGEPEGPGD---PAAAPAEAEEQAVEARQEEEQDLDGEKG-PSSEGPEEED 135
P PG P G P A+ E A + E GE G P GP
Sbjct: 203 QGARGFPGTPGLPGVKGHRGYPGLDGAKGEAGAPGVKGESGS--PGENGSPGPMGPRGLP 260
Query: 136 GE 137
GE
Sbjct: 261 GE 262
Score = 33.9 bits (76), Expect = 0.098
Identities = 40/135 (29%), Positives = 48/135 (35%), Gaps = 41/135 (30%)
Query: 28 RRGAAASPEPARAPPEPAP-----------------PAEATGAP-APSRPCAPEPAASPA 69
++G A +P P P P P ATG P A R P +P
Sbjct: 787 QKGDAGAPGPQGPSGAPGPQGPTGVTGPKGARGAQGPPGATGFPGAAGRVGPPGSNGNPG 846
Query: 70 GPEEPGEPAG-------LGELGEPAGPGEPEGPGDPAAAPAEAEEQAVEARQEEEQDLDG 122
P PG P+G G+ G P GEP G PA P E E G
Sbjct: 847 PPGPPG-PSGKDGPKGARGDSGPPGRAGEP-GLQGPAGPPGEKGE-------------PG 891
Query: 123 EKGPS-SEGPEEEDG 136
+ GPS +EGP G
Sbjct: 892 DDGPSGAEGPPGPQG 906
Score = 33.9 bits (76), Expect = 0.098
Identities = 18/48 (37%), Positives = 22/48 (45%), Gaps = 1/48 (2%)
Query: 52 GAPAPSRPCAPEPAASPAGPEEP-GEPAGLGELGEPAGPGEPEGPGDP 98
G P P P + A+ PAGP P G P +G G+ G P G P
Sbjct: 1071 GLPGPPGPSGDQGASGPAGPSGPRGPPGPVGPSGKDGANGIPGPIGPP 1118
Score = 33.1 bits (74), Expect = 0.17
Identities = 23/78 (29%), Positives = 33/78 (42%), Gaps = 15/78 (19%)
Query: 60 CAPEPAASPAGPEEPGEPAGLGELGEPAGPGEPEGPGDPAAAPAEAEEQAVEARQEEEQD 119
C + P + GEP + ++ P GP P+GP A EQ + ++
Sbjct: 23 CQGQDVRQPGPKGQKGEPGDIKDIVGPKGPPGPQGP---------AGEQGPRGDRGDK-- 71
Query: 120 LDGEKGPSSEGPEEEDGE 137
GEKG + GP DGE
Sbjct: 72 --GEKG--APGPRGRDGE 85
Score = 32.7 bits (73), Expect = 0.22
Identities = 36/118 (30%), Positives = 45/118 (38%), Gaps = 14/118 (11%)
Query: 30 GAAASPEPARAPPEPAPPAEATGAPAPSRPCAP-----EPAAS-PAGPEEPGEPAGL--- 80
G + P A + PP A G P P P EP P+G E P P GL
Sbjct: 852 GPSGKDGPKGARGDSGPPGRA-GEPGLQGPAGPPGEKGEPGDDGPSGAEGPPGPQGLAGQ 910
Query: 81 -GELGEPAGPGEPEGPGDPAAAPAEAEEQAVEARQEEEQDLDGEKGPSS-EGPEEEDG 136
G +G P GE PG P + ++ A A ++ G GP GP E G
Sbjct: 911 RGIVGLPGQRGERGFPGLPGPSGEPGKQGAPGA--SGDRGPPGPVGPPGLTGPAGEPG 966
Score = 32.3 bits (72), Expect = 0.29
Identities = 34/122 (27%), Positives = 40/122 (32%), Gaps = 14/122 (11%)
Query: 29 RGAAASPEPARAPPEPAPPAEATGAPAPSRPCAPEPAASPAGPEEPGEPAGLGELGEPAG 88
+G P A E P + +P +P P P E G G G
Sbjct: 218 KGHRGYPGLDGAKGEAGAPGVKGESGSPGENGSPGPMGPRGLPGERGRTGPAGAAGARGN 277
Query: 89 PGEPE------------GPGDPAAAPAEAEEQAVEAR-QEEEQDLDGEKG-PSSEGPEEE 134
G+P GPG P A A+ E AR E Q GE G P S GP
Sbjct: 278 DGQPGPAGPPGPVGPAGGPGFPGAPGAKGEAGPTGARGPEGAQGPRGEPGTPGSPGPAGA 337
Query: 135 DG 136
G
Sbjct: 338 SG 339
Score = 32.0 bits (71), Expect = 0.37
Identities = 43/155 (27%), Positives = 48/155 (30%), Gaps = 47/155 (30%)
Query: 30 GAAASPEPARA--------PPEPAPPAEATGAPAPSRPCAPEPAASPAGPE-EPGEPAGL 80
G P PA A PP PA A A GAP P A AGP G+P
Sbjct: 720 GPIGPPGPAGANGEKGEVGPPGPAGSAGARGAPGERGETGPPGPAGFAGPPGADGQPGAK 779
Query: 81 GELGE--------------PAGPGEPEGP-------------------GDPAAA----PA 103
GE GE P+G P+GP G P AA P
Sbjct: 780 GEQGEAGQKGDAGAPGPQGPSGAPGPQGPTGVTGPKGARGAQGPPGATGFPGAAGRVGPP 839
Query: 104 EAEEQAVEARQEEEQDLDGEKGPSSE-GPEEEDGE 137
+ DG KG + GP GE
Sbjct: 840 GSNGNPGPPGPPGPSGKDGPKGARGDSGPPGRAGE 874
Score = 31.6 bits (70), Expect = 0.49
Identities = 36/122 (29%), Positives = 41/122 (33%), Gaps = 9/122 (7%)
Query: 30 GAAASPEPA--RAPPEPAPPAEATGAPA-PSRPCAPEPAASPAGPEEPGEPAGLGELGEP 86
G A P A R PP P A G P P P P GE G GE
Sbjct: 186 GEAGKPGKAGERGPPGPQG---ARGFPGTPGLPGVKGHRGYPGLDGAKGEAGAPGVKGES 242
Query: 87 AGPGEPEGPG--DPAAAPAEAEEQAVEARQEEEQDLDGEKGPSSEGPEEEDGEGFSFKYS 144
PGE PG P P E + A + DG+ GP+ G F +
Sbjct: 243 GSPGENGSPGPMGPRGLPGE-RGRTGPAGAAGARGNDGQPGPAGPPGPVGPAGGPGFPGA 301
Query: 145 PG 146
PG
Sbjct: 302 PG 303
Score = 31.2 bits (69), Expect = 0.64
Identities = 30/109 (27%), Positives = 36/109 (33%), Gaps = 5/109 (4%)
Query: 33 ASPEPARAPPEPAPPAEATGAPAPSRPCAPEPAASPAGPE-EPGEPAGLGELGE--PAGP 89
A P A+ PP GA + P GPE PG+ G G G P GP
Sbjct: 668 AGPPGAQGPPGLQGMPGERGAAGIAGPKGDRGDVGEKGPEGAPGKDGGRGLTGPIGPPGP 727
Query: 90 GEPEGPGDPAAAPAEAEEQAVEARQEEEQDLDGEKGPSS-EGPEEEDGE 137
G P A E + G GP+ GP DG+
Sbjct: 728 AGANGEKGEVGPPGPAGSAGARGAPGERGE-TGPPGPAGFAGPPGADGQ 775
Score = 30.0 bits (66), Expect = 1.4
Identities = 34/121 (28%), Positives = 39/121 (32%), Gaps = 13/121 (10%)
Query: 29 RGAAASPEPARAPPEPAPPAEATGAPAPSRPCAPEPAASPAGPEE-PGEPAGLGELGEPA 87
RG P A P P+ A G P P+ A G PG GE G+
Sbjct: 491 RGLTGRPGDA-GPQGKVGPSGAPGEDGRPGPPGPQGARGQPGVMGFPGPKGANGEPGKAG 549
Query: 88 GPGEPEGPG-------DPAAAPAEAEEQAVEARQEEEQDLDGEKG----PSSEGPEEEDG 136
G P PG D A A A + EQ G G P GP E G
Sbjct: 550 EKGLPGAPGLRGLPGKDGETGAAGPPGPAGPAGERGEQGAPGPSGFQGLPGPPGPPGEGG 609
Query: 137 E 137
+
Sbjct: 610 K 610
Score = 29.6 bits (65), Expect = 1.9
Identities = 21/59 (35%), Positives = 22/59 (37%), Gaps = 8/59 (13%)
Query: 41 PPEPAPPAEATGAPAPSRPCAPEPAASPAGPEEPGEPAGL-GELGEPAGPGEPEGPGDP 98
P P P E AP A+ GP P P GL G GEP G P G P
Sbjct: 926 PGLPGPSGEPGKQGAPG-------ASGDRGPPGPVGPPGLTGPAGEPGREGSPGADGPP 977
Score = 29.6 bits (65), Expect = 1.9
Identities = 20/72 (27%), Positives = 21/72 (29%), Gaps = 25/72 (34%)
Query: 52 GAPAPSRPCAPEPAASPAGPEEPGEPAG-------------------------LGELGEP 86
G P PS A P+GP P P G G G P
Sbjct: 1074 GPPGPSGDQGASGPAGPSGPRGPPGPVGPSGKDGANGIPGPIGPPGPRGRSGETGPAGPP 1133
Query: 87 AGPGEPEGPGDP 98
PG P PG P
Sbjct: 1134 GNPGPPGPPGPP 1145
Score = 29.3 bits (64), Expect = 2.4
Identities = 35/128 (27%), Positives = 41/128 (32%), Gaps = 37/128 (28%)
Query: 28 RRGAAASPE---PARAPPEPAPPAEATGAPAPSRPCAPEPAASPAGPE-------EPGEP 77
+RGA P P P E P G P P+ A GP G+P
Sbjct: 421 KRGARGEPGGVGPIGPPGERGAPGNR-GFPGQDGLAGPKGAPGERGPSGLAGPKGANGDP 479
Query: 78 AGLGELGEPAGPGEPEGPGD--------PAAAPAEAEEQAVEARQEEEQDLDGEKGPSSE 129
GE G P G PGD P+ AP E DG GP
Sbjct: 480 GRPGEPGLPGARGLTGRPGDAGPQGKVGPSGAPGE----------------DGRPGP--P 521
Query: 130 GPEEEDGE 137
GP+ G+
Sbjct: 522 GPQGARGQ 529
Score = 29.3 bits (64), Expect = 2.4
Identities = 26/89 (29%), Positives = 32/89 (35%), Gaps = 11/89 (12%)
Query: 52 GAPAPSRPCAPEPAASPAGPEEPGEPAGLGELGEPAGPGEPEGPGDPAAAPAEAEEQAVE 111
G P PS + A +G P P G L PA GEP G P A + A
Sbjct: 927 GLPGPSGEPGKQGAPGASGDRGPPGPVGPPGLTGPA--GEPGREGSPGADGPPGRDGAAG 984
Query: 112 ARQEEEQDLDGEKG----PSSEGPEEEDG 136
+ + GE G P + GP G
Sbjct: 985 VKGDR-----GETGAVGAPGAPGPPGSPG 1008
Score = 29.3 bits (64), Expect = 2.4
Identities = 29/97 (29%), Positives = 33/97 (34%), Gaps = 11/97 (11%)
Query: 42 PEPAPPAEATGAPAPSRPCAPEPAASPAGPEEPGEPAGLGELGEPAGPGEPEGPGDPAAA 101
P P+ GAP S P P GP PG GE G PG PG AA
Sbjct: 929 PGPSGEPGKQGAPGASGDRGPP---GPVGP--PGLTGPAGEPGREGSPGADGPPGRDGAA 983
Query: 102 PAEAEEQAVEARQEEEQDLDGEKG-PSSEGPEEEDGE 137
+ + A G G P S GP G+
Sbjct: 984 GVKGDRGETGA-----VGAPGAPGPPGSPGPAGPTGK 1015
>gi|32307177 forkhead box G1 [Homo sapiens]
Length = 489
Score = 51.2 bits (121), Expect = 6e-07
Identities = 48/164 (29%), Positives = 67/164 (40%), Gaps = 21/164 (12%)
Query: 35 PEPARAPPEPAPPA----EATGAPAPSRPCAPEPAASPAGPEEPGEPA-------GLGEL 83
P + PP P PPA + GAPA P+ P P P A GLG
Sbjct: 68 PPQQQQPPPPPPPAPQPPQTRGAPAADDDKGPQQLLLPPPPPPPPAAALDGAKADGLGGK 127
Query: 84 GEPAGPGEPEGPGDPAAAPAEAEEQAVEARQEEEQDLDGEKGPSSEGPEEEDGEGFSFKY 143
GEP G GPG+ A + +E+ A EE++ GE G EG +E GE + KY
Sbjct: 128 GEPGG-----GPGELAPVGPDEKEKGAGAGGEEKKGA-GEGGKDGEGGKE--GEKKNGKY 179
Query: 144 SPGKLRGNQYKKMMTKEELEEEQRVQ--KEQLAAIFKLMKDNKE 185
N M ++ E+ + E + F ++NK+
Sbjct: 180 EKPPFSYNALIMMAIRQSPEKRLTLNGIYEFIMKNFPYYRENKQ 223
>gi|24308115 interferon regulatory factor 2 binding protein 1 [Homo
sapiens]
Length = 584
Score = 50.8 bits (120), Expect = 8e-07
Identities = 41/109 (37%), Positives = 45/109 (41%), Gaps = 15/109 (13%)
Query: 35 PEPARAPPEPAP---PAEATGAP--APSRPCAPEPAASPAGPEEPGEPAGLGELGE---- 85
P PA A P+ P PA G P APSR AP P A PE GE AG E
Sbjct: 344 PAPAEALPQQYPEPAPAALCGPPPRAPSRNLAPTPRRRKASPEPEGEAAGKMTTEEQQQR 403
Query: 86 ----PAGPGEPEGPGDPAAAPAEAEEQAVEARQEEEQDLDGEKGPSSEG 130
P GP E PG P +P A + EA +D G GP G
Sbjct: 404 HWVAPGGPYSAETPGVP--SPIAALKNVAEALGHSPKDPGGGGGPVRAG 450
>gi|116256445 nuclear receptor co-repressor 2 isoform 2 [Homo
sapiens]
Length = 2462
Score = 50.4 bits (119), Expect = 1e-06
Identities = 41/108 (37%), Positives = 51/108 (47%), Gaps = 15/108 (13%)
Query: 35 PEPARAPPEPAPPAEATGAPAPSRPCAPEPAASPAGPEEPGEPAGLGELGEPAGPGEPEG 94
PE AP EP P +EATGAP P P P P+A P P P E E E P
Sbjct: 770 PEDIPAPTEPTPASEATGAPTPP-PAPPSPSAPP--PVVPKE-----EKEEETAAAPPVE 821
Query: 95 PGDPAAAPAEAEEQAVEARQEEEQ-----DLDGEKGPSSEGPEEEDGE 137
G+ PA AEE AV+ + EE + E+GP ++G + E E
Sbjct: 822 EGEEQKPPA-AEELAVDTGKAEEPVKSECTEEAEEGP-AKGKDAEAAE 867
Score = 37.7 bits (86), Expect = 0.007
Identities = 47/186 (25%), Positives = 62/186 (33%), Gaps = 41/186 (22%)
Query: 28 RRGAAASPEPARAPP-----------------EPAPPAEATGAPAPSRPCAPEP---AAS 67
++ AA+ E A PP E AEAT + P P AA
Sbjct: 684 KKAPAAASEEAAFPPVVEDEEMEASGVSGNEEEMVEEAEATVNNSSDTESIPSPHTEAAK 743
Query: 68 PAGPEEPGEPAGLGELGEPAGPGEPE------------------GPGDPAAAPAEAEEQA 109
G P PA LG G P GP P P P A P+ +
Sbjct: 744 DTGQNGPKPPATLGADGPPPGPPTPPPEDIPAPTEPTPASEATGAPTPPPAPPSPSAPPP 803
Query: 110 VEARQEEEQDLDGEKGPSSEGPEEEDGEGFSFKYSPGKLRGNQYKKMMTKEELEEEQRVQ 169
V ++E+E++ P EG E++ GK + K EE EE
Sbjct: 804 VVPKEEKEEE-TAAAPPVEEGEEQKPPAAEELAVDTGK--AEEPVKSECTEEAEEGPAKG 860
Query: 170 KEQLAA 175
K+ AA
Sbjct: 861 KDAEAA 866
Score = 31.6 bits (70), Expect = 0.49
Identities = 27/75 (36%), Positives = 34/75 (45%), Gaps = 9/75 (12%)
Query: 42 PEPAPPAEATGAPAPSRPCAPEPAASPAGPEEPGEPAGLGELGEPAGPGEPEGP--GDPA 99
P P PP E A P AP+P+A P PG P LG L + A P P P +P
Sbjct: 1045 PFPVPPREVIKAS----PHAPDPSAFSYAP--PGHPLPLG-LHDTARPVLPRPPTISNPP 1097
Query: 100 AAPAEAEEQAVEARQ 114
+ A+ +V RQ
Sbjct: 1098 PLISSAKHPSVLERQ 1112
Score = 30.4 bits (67), Expect = 1.1
Identities = 26/84 (30%), Positives = 33/84 (39%), Gaps = 2/84 (2%)
Query: 26 LVRRGAAASPEPARAPPEPAPPAEATGAPAPSRPCAPEPAASPA-GPEEPG-EPAGLGEL 83
L +R AA P EP A PAP P P+ + P++PG P G
Sbjct: 949 LKQRAAAIPPIQVTKVHEPPREDAAPTKPAPPAPPPPQNLQPESDAPQQPGSSPRGKSRS 1008
Query: 84 GEPAGPGEPEGPGDPAAAPAEAEE 107
P E E P A AEA++
Sbjct: 1009 PAPPADKEAEKPVFFPAFAAEAQK 1032
>gi|116256453 nuclear receptor co-repressor 2 isoform 1 [Homo
sapiens]
Length = 2524
Score = 50.4 bits (119), Expect = 1e-06
Identities = 41/108 (37%), Positives = 51/108 (47%), Gaps = 15/108 (13%)
Query: 35 PEPARAPPEPAPPAEATGAPAPSRPCAPEPAASPAGPEEPGEPAGLGELGEPAGPGEPEG 94
PE AP EP P +EATGAP P P P P+A P P P E E E P
Sbjct: 787 PEDIPAPTEPTPASEATGAPTPP-PAPPSPSAPP--PVVPKE-----EKEEETAAAPPVE 838
Query: 95 PGDPAAAPAEAEEQAVEARQEEEQ-----DLDGEKGPSSEGPEEEDGE 137
G+ PA AEE AV+ + EE + E+GP ++G + E E
Sbjct: 839 EGEEQKPPA-AEELAVDTGKAEEPVKSECTEEAEEGP-AKGKDAEAAE 884
Score = 38.1 bits (87), Expect = 0.005
Identities = 40/156 (25%), Positives = 52/156 (33%), Gaps = 10/156 (6%)
Query: 27 VRRGAAASPEPARAPPE----PAPPAEA---TGAPAPSRPCAPEPAASPAGPEEPGEPAG 79
V RG + P + P+P EA TG P P P GP P P
Sbjct: 731 VPRGECSGPATVNNSSDTESIPSPHTEAAKDTGQNGPKPPATLGADGPPPGPPTP-PPED 789
Query: 80 LGELGEPAGPGEPEGPGDPAAAPAEAEEQAVEARQEEEQDLDGEKGPSSEGPEEEDGEGF 139
+ EP E G P AP +EE+++ P EG E++
Sbjct: 790 IPAPTEPTPASEATGAPTPPPAPPSPSAPPPVVPKEEKEEETAAAPPVEEGEEQKPPAAE 849
Query: 140 SFKYSPGKLRGNQYKKMMTKEELEEEQRVQKEQLAA 175
GK + K EE EE K+ AA
Sbjct: 850 ELAVDTGK--AEEPVKSECTEEAEEGPAKGKDAEAA 883
Score = 34.3 bits (77), Expect = 0.075
Identities = 33/92 (35%), Positives = 40/92 (43%), Gaps = 19/92 (20%)
Query: 26 LVRRGAAASP------EPAR---APPEPAPPAEATGAPAPSRPCAPEPAASPAGPEEPG- 75
L +R AA P EP R AP +PAPPA P P + PE A P++PG
Sbjct: 966 LKQRAAAIPPIVTKVHEPPREDAAPTKPAPPA-----PPPPQNLQPESDA----PQQPGS 1016
Query: 76 EPAGLGELGEPAGPGEPEGPGDPAAAPAEAEE 107
P G P E E P A AEA++
Sbjct: 1017 SPRGKSRSPAPPADKEAEKPVFFPAFAAEAQK 1048
Score = 31.6 bits (70), Expect = 0.49
Identities = 27/75 (36%), Positives = 34/75 (45%), Gaps = 9/75 (12%)
Query: 42 PEPAPPAEATGAPAPSRPCAPEPAASPAGPEEPGEPAGLGELGEPAGPGEPEGP--GDPA 99
P P PP E A P AP+P+A P PG P LG L + A P P P +P
Sbjct: 1061 PFPVPPREVIKAS----PHAPDPSAFSYAP--PGHPLPLG-LHDTARPVLPRPPTISNPP 1113
Query: 100 AAPAEAEEQAVEARQ 114
+ A+ +V RQ
Sbjct: 1114 PLISSAKHPSVLERQ 1128
>gi|153070260 myristoylated alanine-rich protein kinase C substrate
[Homo sapiens]
Length = 332
Score = 50.1 bits (118), Expect = 1e-06
Identities = 44/125 (35%), Positives = 54/125 (43%), Gaps = 17/125 (13%)
Query: 31 AAASPEPARAPPEPAPPAEATGAPAPSRPCAPEPAASPAGPEEPGEPAGLGELGEPAGPG 90
AA EPA A A P+ A P+ APE ASP E P E G
Sbjct: 66 AADKEEPAAAGSGAASPSAAEKGE-PAAAAAPEAGASPVEKEAPAE-------------G 111
Query: 91 EPEGPGDPAAAPAEAEEQAVEARQEEEQDLDGEKGPSSEGPEEEDGEGFSFKYSPGKLRG 150
E PG P AA EA A + +D PS+E P+++ + FSFK S KL G
Sbjct: 112 EAAEPGSPTAAEGEAASAASSTSSPKAED-GATPSPSNETPKKKK-KRFSFKKS-FKLSG 168
Query: 151 NQYKK 155
+KK
Sbjct: 169 FSFKK 173
Score = 39.3 bits (90), Expect = 0.002
Identities = 37/112 (33%), Positives = 44/112 (39%), Gaps = 12/112 (10%)
Query: 31 AAASPEPARAPPEPAPPAEATGAPAPSRPCAPEPAASPAGP--------EEPGEPAGLGE 82
AA A P+ A P EA A AP +P A + + P EE G A E
Sbjct: 223 AAGEEGAAGGDPQEAKPQEA--AVAPEKPPASDETKAAEEPSKVEEKKAEEAGASAAACE 280
Query: 83 LGEPAGPG-EPEGPGDPAAAP-AEAEEQAVEARQEEEQDLDGEKGPSSEGPE 132
AGPG PE PA P A A A A +E Q + P +E E
Sbjct: 281 APSAAGPGAPPEQEAAPAEEPAAAAASSACAAPSQEAQPECSPEAPPAEAAE 332
Score = 37.4 bits (85), Expect = 0.009
Identities = 33/105 (31%), Positives = 40/105 (38%), Gaps = 6/105 (5%)
Query: 38 ARAPPEPAPPAEATGAPAPSRPCAPEPAASPAGPEEPGEPAGLGELGEPAGPGEPEGPGD 97
A AP EA G A + A AAS PGE A GE G G + P +
Sbjct: 184 AEAPAAEGGKDEAAGGAAAA--AAEAGAASGEQAAAPGEEAAAGEEGAAGGDPQEAKPQE 241
Query: 98 PAAA----PAEAEEQAVEARQEEEQDLDGEKGPSSEGPEEEDGEG 138
A A PA E +A E + E+ E G S+ E G
Sbjct: 242 AAVAPEKPPASDETKAAEEPSKVEEKKAEEAGASAAACEAPSAAG 286
Score = 30.4 bits (67), Expect = 1.1
Identities = 20/47 (42%), Positives = 23/47 (48%), Gaps = 3/47 (6%)
Query: 30 GAAASPEPARAP-PEPAPPAEATGAPAPSRPCAPE--PAASPAGPEE 73
G A PE AP EPA A ++ APS+ PE P A PA E
Sbjct: 286 GPGAPPEQEAAPAEEPAAAAASSACAAPSQEAQPECSPEAPPAEAAE 332
Score = 28.5 bits (62), Expect = 4.1
Identities = 24/78 (30%), Positives = 29/78 (37%), Gaps = 18/78 (23%)
Query: 30 GAAASPEPARAPPEPAPPAEATGAPAPSRPCAPEPAASPAGPEEPGEPAGLGELGEPAGP 89
GA+A+ A + P P E APA EEP A P+
Sbjct: 273 GASAAACEAPSAAGPGAPPEQEAAPA----------------EEPAAAAASSACAAPSQE 316
Query: 90 GEPEGPGDPAAAPAEAEE 107
+PE P A PAEA E
Sbjct: 317 AQPE--CSPEAPPAEAAE 332
>gi|111118972 collagen, type XI, alpha 2 isoform 2 preproprotein [Homo
sapiens]
Length = 1650
Score = 49.7 bits (117), Expect = 2e-06
Identities = 39/116 (33%), Positives = 44/116 (37%), Gaps = 8/116 (6%)
Query: 29 RGAAASPEPARAPPEPAPPAEA--TGAPAPSRPCAPEPAASPAGPE----EPGEPAGLGE 82
RG P P P P E TG P P P PAGP G P G+G
Sbjct: 1060 RGFNGPPGPIGLQGLPGPSGEKGETGDVGPMGPPGPPGPRGPAGPNGADGPQGPPGGVGN 1119
Query: 83 LGEPAGPGEPEGPGDPAAAPAEAEEQAVEARQEE-EQDLDGEKG-PSSEGPEEEDG 136
LG P GEP G P + R E+ E GE G P +GP +DG
Sbjct: 1120 LGPPGEKGEPGESGSPGIQGEPGVKGPRGERGEKGESGQPGEPGPPGPKGPTGDDG 1175
Score = 40.0 bits (92), Expect = 0.001
Identities = 32/110 (29%), Positives = 38/110 (34%), Gaps = 16/110 (14%)
Query: 41 PPEPAPPAEATGAPAPSRPCA-------------PEPAASPAGPEEPGEPAGLGELGEPA 87
PP P PA GA P P P + SP EPG GE GE
Sbjct: 1095 PPGPRGPAGPNGADGPQGPPGGVGNLGPPGEKGEPGESGSPGIQGEPGVKGPRGERGEKG 1154
Query: 88 GPGEPEGPGDPAAAPAEAEEQAVEARQEEEQDLDGEKGPSSE-GPEEEDG 136
G+P PG P ++ G+ GP E GP +DG
Sbjct: 1155 ESGQPGEPGPPGPKGPTGDDG--PKGNPGPVGFPGDPGPPGEGGPRGQDG 1202
Score = 38.5 bits (88), Expect = 0.004
Identities = 36/119 (30%), Positives = 40/119 (33%), Gaps = 20/119 (16%)
Query: 30 GAAASP-----EPARAPPEPAPPAEATGAPAPSRPCAPEPAASPAGPEEPGEPAGLGELG 84
G A P E PP PA GA P P P GP PG G G
Sbjct: 908 GTAGGPGLKGNEGPSGPPGPAGSPGERGAAGSGGPIGPPGRPGPQGP--PGAAGEKGVPG 965
Query: 85 E--PAGPGEPEGPGDPAAAPAEAEEQAVEARQEEEQDLDGEKG----PSSEGPEEEDGE 137
E P GP +G P P A V DG+KG P +G + GE
Sbjct: 966 EKGPIGPTGRDGVQGPVGLPGPAGPPGVAGE-------DGDKGEVGDPGQKGTKGNKGE 1017
Score = 37.7 bits (86), Expect = 0.007
Identities = 34/122 (27%), Positives = 41/122 (33%), Gaps = 12/122 (9%)
Query: 29 RGAAASPEPARAPPEPAPPAEA--TGAPAPSRPCAPEPAASPAGPEEPGEPAGLGELGEP 86
RG + P EP PP TG P P P P P PGE G+ G
Sbjct: 1147 RGERGEKGESGQPGEPGPPGPKGPTGDDGPKGN--PGPVGFPGDPGPPGEGGPRGQDGAK 1204
Query: 87 AGPGEPEGPGDPAAAPAEAEEQAVEARQEEEQDLDGEKGPSSEGPEEEDGEGFSFKYSPG 146
GE PG P +P E G++GP+ E G K PG
Sbjct: 1205 GDRGEDGEPGQP-GSPGPTGENGPPGPL-------GKRGPAGSPGSEGRQGGKGAKGDPG 1256
Query: 147 KL 148
+
Sbjct: 1257 AI 1258
Score = 37.4 bits (85), Expect = 0.009
Identities = 38/121 (31%), Positives = 44/121 (36%), Gaps = 31/121 (25%)
Query: 28 RRGAAASPEPARAPPEPAP------PAE-----ATGAPAPSRPCAPEPAASPAG-PEEPG 75
+ G P P AP + P P E G P P PAG P E G
Sbjct: 876 KEGTKGDPGPPGAPGKDGPAGLRGFPGERGLPGTAGGPGLKGNEGPSGPPGPAGSPGERG 935
Query: 76 EPAGLGELGEPAGPGEPEGPGDPAAAPAEAEEQAVEARQEEEQDLDGEKGPSSEGPEEED 135
G +G P PG P+GP P AA E+ + GEKGP GP D
Sbjct: 936 AAGSGGPIGPPGRPG-PQGP--PGAA--------------GEKGVPGEKGPI--GPTGRD 976
Query: 136 G 136
G
Sbjct: 977 G 977
Score = 37.0 bits (84), Expect = 0.012
Identities = 44/151 (29%), Positives = 50/151 (33%), Gaps = 43/151 (28%)
Query: 29 RGAAASPEPARAPPEPAPP-----AEATGAPAPSRPCAP---EPAASPAGPEEPGEPAGL 80
RGAA S P P P P A G P P P + P G P P G+
Sbjct: 934 RGAAGSGGPIGPPGRPGPQGPPGAAGEKGVPGEKGPIGPTGRDGVQGPVGLPGPAGPPGV 993
Query: 81 ----------------------GELGEPAGPGEPEGP-GDPAAAPAEAEEQAVEAR---- 113
GE G P PG P GP G P AA A+ E A +
Sbjct: 994 AGEDGDKGEVGDPGQKGTKGNKGEHGPPGPPG-PIGPVGQPGAAGADGEPGARGPQGHFG 1052
Query: 114 ---QEEEQDLDGEKGP----SSEGPEEEDGE 137
E + +G GP GP E GE
Sbjct: 1053 AKGDEGTRGFNGPPGPIGLQGLPGPSGEKGE 1083
Score = 36.2 bits (82), Expect = 0.020
Identities = 40/142 (28%), Positives = 52/142 (36%), Gaps = 21/142 (14%)
Query: 26 LVRRGAAASP--EPARAPPEPAPPAEATGAPAPSRPCAPEPAASPAGPE----------E 73
L +RG A SP E + A GAP + P P A GP+ +
Sbjct: 1231 LGKRGPAGSPGSEGRQGGKGAKGDPGAIGAPGKTGPVGPAGPAGKPGPDGLRGLPGSVGQ 1290
Query: 74 PGEPAGLGELGEPAGPGEPEGPGDPAAAPAEAEEQAVE----ARQEEEQDLDGEKG-PSS 128
G P G+ G P G P PG A A+ E+ EQ G++G P
Sbjct: 1291 QGRPGATGQAGPPGPVGPPGLPGLRGDAGAKGEKGHPGLIGLIGPPGEQGEKGDRGLPGP 1350
Query: 129 EGPEEEDGE----GFSFKYSPG 146
+G + GE G S PG
Sbjct: 1351 QGSPGQKGEMGIPGASGPIGPG 1372
Score = 35.4 bits (80), Expect = 0.034
Identities = 31/102 (30%), Positives = 37/102 (36%), Gaps = 29/102 (28%)
Query: 30 GAAASPEPARAPPEPAPPAEA-----TGAPA-------PSRPCAPEPAA----------- 66
G +P P P +P PP E GA P +P +P P
Sbjct: 1175 GPKGNPGPVGFPGDPGPPGEGGPRGQDGAKGDRGEDGEPGQPGSPGPTGENGPPGPLGKR 1234
Query: 67 SPAG-PEEPGEPAGLGELGEP---AGPGE--PEGPGDPAAAP 102
PAG P G G G G+P PG+ P GP PA P
Sbjct: 1235 GPAGSPGSEGRQGGKGAKGDPGAIGAPGKTGPVGPAGPAGKP 1276
Score = 35.0 bits (79), Expect = 0.044
Identities = 29/103 (28%), Positives = 35/103 (33%), Gaps = 22/103 (21%)
Query: 43 EPAPPAE-----ATGAPAPSRPCAPEPAASPAGPEEPGEPAGLGELGEPAGPGE------ 91
EP PP + G P P P P G +PG P G G P PG+
Sbjct: 558 EPGPPGQQGTPGTQGLPGPQGAIGPHGEKGPQG--KPGLPGMPGSDGPPGHPGKEGPPGT 615
Query: 92 -----PEGPGDPAAAPAEAEEQAVEARQEEEQDLDGEKGPSSE 129
P GP P P + V+ + L G KG E
Sbjct: 616 KGNQGPSGPQGPLGYPGPRGVKGVDG----IRGLKGHKGEKGE 654
Score = 35.0 bits (79), Expect = 0.044
Identities = 25/81 (30%), Positives = 28/81 (34%), Gaps = 13/81 (16%)
Query: 29 RGAAASPEPARAPPEPAPPAEA-----TGAPAPSRPCAPEPAASPAGPEEPGEPAGLGEL 83
+G P P P E TG P P P+ AA GP +GE
Sbjct: 805 KGPPGPPGKDGLPGHPGQRGEVGFQGKTGPPGPPGVVGPQGAAGETGP--------MGER 856
Query: 84 GEPAGPGEPEGPGDPAAAPAE 104
G P PG P G P A E
Sbjct: 857 GHPGPPGPPGEQGLPGTAGKE 877
Score = 35.0 bits (79), Expect = 0.044
Identities = 36/109 (33%), Positives = 42/109 (38%), Gaps = 14/109 (12%)
Query: 30 GAAASPEPARAPPEPAPPAEATGAPAPSRPCAPEPAASPAGPEEPGEPAGL-GELGEPAG 88
G + SP P P E +P P P P GP P G G +G P
Sbjct: 1130 GESGSPGIQGEPGVKGPRGERGEKGESGQPGEPGPPG-PKGPTGDDGPKGNPGPVGFPGD 1188
Query: 89 PGEPEGPGDPAAAPAEAEEQAVEARQEEEQDLDGEKG-PSSEGPEEEDG 136
PG P G G P ++ A R E DGE G P S GP E+G
Sbjct: 1189 PG-PPGEGGP-----RGQDGAKGDRGE-----DGEPGQPGSPGPTGENG 1226
Score = 34.3 bits (77), Expect = 0.075
Identities = 37/121 (30%), Positives = 42/121 (34%), Gaps = 12/121 (9%)
Query: 35 PEPARAPPEPAPPAEATGAPAPSRPCAPEPAASPAGPEEPGEPAGLGELGEPAGPGEPEG 94
P R P P P G P P P P P P PG+ +G G+ PG P
Sbjct: 786 PPGERGLPGPQGP---NGFPGPKGP--PGPPGKDGLPGHPGQRGEVGFQGKTGPPGPPGV 840
Query: 95 PGDPAAA----PAEAEEQAVEARQEEEQDLDGEKGPSSEGPEEEDG-EGFSFKYSPGKLR 149
G AA P EQ L G G EG + + G G K P LR
Sbjct: 841 VGPQGAAGETGPMGERGHPGPPGPPGEQGLPGTAG--KEGTKGDPGPPGAPGKDGPAGLR 898
Query: 150 G 150
G
Sbjct: 899 G 899
Score = 33.5 bits (75), Expect = 0.13
Identities = 33/117 (28%), Positives = 39/117 (33%), Gaps = 29/117 (24%)
Query: 29 RGAAASPEPA---RAPPEPAPPAEATGAPAPSRPCAPEPAASPAGPEEPGEPAGLGELGE 85
+G A EP PP P PA G P +P +PGE G G
Sbjct: 299 KGEPAVLEPGMLVEGPPGPEGPAGLIGPPGIQ--------GNPGPVGDPGERGPPGRAGL 350
Query: 86 PAGPGEPEGPG----------------DPAAAPAEAEEQAVEARQEEEQDLDGEKGP 126
P G P PG P A EA+ QA+ Q+ L G GP
Sbjct: 351 PGSDGAPGPPGTSLMLPFRFGSGGGDKGPVVAAQEAQAQAI--LQQARLALRGPPGP 405
Score = 32.3 bits (72), Expect = 0.29
Identities = 32/97 (32%), Positives = 39/97 (40%), Gaps = 19/97 (19%)
Query: 52 GAPAPSRPCAPEPAASPAGPE-EPGEPAGLGE---LGEPAGPGEP--EGP----GDPAAA 101
G P PE GP +PG P +GE LG P PG P +GP G P
Sbjct: 674 GVPGSRGEDGPEGPKGRTGPTGDPGPPGLMGEKGKLGVPGLPGYPGRQGPKGSLGFPGFP 733
Query: 102 PAEAEEQAVEARQEEEQDLDGEKGPSSE-GPEEEDGE 137
A E+ A + L G+ GP E GP G+
Sbjct: 734 GASGEKGA--------RGLSGKSGPRGERGPTGPRGQ 762
Score = 31.2 bits (69), Expect = 0.64
Identities = 33/121 (27%), Positives = 44/121 (36%), Gaps = 21/121 (17%)
Query: 29 RGAAASPEPARAPPEPAPPAEATGAPAPSRPC---APEPAASPAGPE------EPGEPAG 79
+G P P +P + G P S P P PAGP+ PG P
Sbjct: 1342 KGDRGLPGPQGSPGQKGE----MGIPGASGPIGPGGPPGLPGPAGPKGAKGATGPGGPK- 1396
Query: 80 LGELGEPAGPGEPEGPGD-----PAAAPAEAEEQAVEAR-QEEEQDLDGEKGPSSEGPEE 133
GE G PG P PG+ P P + +R +E++ + P S G E
Sbjct: 1397 -GEKGVQGPPGHPGPPGEVIQPLPIQMPKKTRRSVDGSRLMQEDEAIPTGGAPGSPGGLE 1455
Query: 134 E 134
E
Sbjct: 1456 E 1456
Score = 30.8 bits (68), Expect = 0.83
Identities = 33/132 (25%), Positives = 42/132 (31%), Gaps = 12/132 (9%)
Query: 30 GAAASPEPARAPPEPAPPAEA--TGAPAPSRPCAPEPAASPAGPEEPGEPAGLGELGEPA 87
GA P P E E G P S P P GP P G+ + P
Sbjct: 491 GAQGLPGPPGEDGERGDDGEIGPRGLPGES---GPRGLLGPKGPPGIPGPPGVRGMDGPQ 547
Query: 88 GPGEPEGPGDPAAAPAEAEEQAVEARQEEEQDL--DGEKGPSSEG-----PEEEDGEGFS 140
GP GP P + + + + GEKGP + P + G
Sbjct: 548 GPKGSLGPQGEPGPPGQQGTPGTQGLPGPQGAIGPHGEKGPQGKPGLPGMPGSDGPPGHP 607
Query: 141 FKYSPGKLRGNQ 152
K P +GNQ
Sbjct: 608 GKEGPPGTKGNQ 619
Score = 29.3 bits (64), Expect = 2.4
Identities = 30/97 (30%), Positives = 33/97 (34%), Gaps = 25/97 (25%)
Query: 62 PEPAASPAGPEEPGEPAGLGELGEPAGPGEPEG-PGDPAAAPAEAEEQAVEARQ------ 114
P P P P GE LG P GP P+G G P A A AR
Sbjct: 412 PGPLGQPGSPGLKGESGDLG----PQGPRGPQGLTGPPGKAGRRGRAGADGARGMPGDPG 467
Query: 115 -------EEEQDLDGEKGPSSE-------GPEEEDGE 137
+ L GEKG + GP EDGE
Sbjct: 468 VKGDRGFDGLPGLPGEKGHRGDTGAQGLPGPPGEDGE 504
Score = 29.3 bits (64), Expect = 2.4
Identities = 27/105 (25%), Positives = 36/105 (34%), Gaps = 15/105 (14%)
Query: 37 PARAPPEPAPPAEA--TGAPAPSRPCAPEPAASPAGPEE-------PGEPAGLGELGEPA 87
P P P PP G P P+ P G + PG +G GE
Sbjct: 528 PKGPPGIPGPPGVRGMDGPQGPKGSLGPQGEPGPPGQQGTPGTQGLPGPQGAIGPHGEKG 587
Query: 88 GPGEPEGPGDPAAAPAEAEEQAVEARQEEEQDLDGEKGPSS-EGP 131
G+P PG P ++ +E G +GPS +GP
Sbjct: 588 PQGKPGLPGMPG-----SDGPPGHPGKEGPPGTKGNQGPSGPQGP 627
Score = 28.5 bits (62), Expect = 4.1
Identities = 25/95 (26%), Positives = 31/95 (32%), Gaps = 5/95 (5%)
Query: 47 PAEATGAPAPSRPCAPEPAASPAGPEEPGEPAGLGELGEPAGPGEPEGPGDPAAAPAEAE 106
P G P A +G + P P G L P GP GP P P + +
Sbjct: 756 PTGPRGQRGPRGATGKSGAKGTSGGDGPHGPPGERGLPGPQGPNGFPGPKGPPGPPGK-D 814
Query: 107 EQAVEARQEEEQDLDGEKGPSSE----GPEEEDGE 137
Q E G+ GP GP+ GE
Sbjct: 815 GLPGHPGQRGEVGFQGKTGPPGPPGVVGPQGAAGE 849
Score = 28.1 bits (61), Expect = 5.4
Identities = 24/83 (28%), Positives = 32/83 (38%), Gaps = 14/83 (16%)
Query: 68 PAGPEEPGEPAGLGELGEPAGPGEPEGPGD-----PAAAPAEAEEQAVEARQEEE----- 117
P P E G G G P PGE GD P P E+ + + +
Sbjct: 478 PGLPGEKGHRGDTGAQGLPGPPGEDGERGDDGEIGPRGLPGESGPRGLLGPKGPPGIPGP 537
Query: 118 ---QDLDGEKGP-SSEGPEEEDG 136
+ +DG +GP S GP+ E G
Sbjct: 538 PGVRGMDGPQGPKGSLGPQGEPG 560
Score = 27.3 bits (59), Expect = 9.2
Identities = 27/102 (26%), Positives = 33/102 (32%), Gaps = 28/102 (27%)
Query: 23 AWLLVRRGAAASPEPARAPPEPAPPAEA-----TGAPAP--SRPCAPEPAASPAGPEEP- 74
A L+ G +P P P E PP A GAP P + P S G + P
Sbjct: 321 AGLIGPPGIQGNPGPVGDPGERGPPGRAGLPGSDGAPGPPGTSLMLPFRFGSGGGDKGPV 380
Query: 75 --------------------GEPAGLGELGEPAGPGEPEGPG 96
G P +G G P G+P PG
Sbjct: 381 VAAQEAQAQAILQQARLALRGPPGPMGYTGRPGPLGQPGSPG 422
>gi|111118968 collagen, type XI, alpha 2 isoform 3 preproprotein [Homo
sapiens]
Length = 1629
Score = 49.7 bits (117), Expect = 2e-06
Identities = 39/116 (33%), Positives = 44/116 (37%), Gaps = 8/116 (6%)
Query: 29 RGAAASPEPARAPPEPAPPAEA--TGAPAPSRPCAPEPAASPAGPE----EPGEPAGLGE 82
RG P P P P E TG P P P PAGP G P G+G
Sbjct: 1039 RGFNGPPGPIGLQGLPGPSGEKGETGDVGPMGPPGPPGPRGPAGPNGADGPQGPPGGVGN 1098
Query: 83 LGEPAGPGEPEGPGDPAAAPAEAEEQAVEARQEE-EQDLDGEKG-PSSEGPEEEDG 136
LG P GEP G P + R E+ E GE G P +GP +DG
Sbjct: 1099 LGPPGEKGEPGESGSPGIQGEPGVKGPRGERGEKGESGQPGEPGPPGPKGPTGDDG 1154
Score = 40.0 bits (92), Expect = 0.001
Identities = 32/110 (29%), Positives = 38/110 (34%), Gaps = 16/110 (14%)
Query: 41 PPEPAPPAEATGAPAPSRPCA-------------PEPAASPAGPEEPGEPAGLGELGEPA 87
PP P PA GA P P P + SP EPG GE GE
Sbjct: 1074 PPGPRGPAGPNGADGPQGPPGGVGNLGPPGEKGEPGESGSPGIQGEPGVKGPRGERGEKG 1133
Query: 88 GPGEPEGPGDPAAAPAEAEEQAVEARQEEEQDLDGEKGPSSE-GPEEEDG 136
G+P PG P ++ G+ GP E GP +DG
Sbjct: 1134 ESGQPGEPGPPGPKGPTGDDG--PKGNPGPVGFPGDPGPPGEGGPRGQDG 1181
Score = 38.5 bits (88), Expect = 0.004
Identities = 36/119 (30%), Positives = 40/119 (33%), Gaps = 20/119 (16%)
Query: 30 GAAASP-----EPARAPPEPAPPAEATGAPAPSRPCAPEPAASPAGPEEPGEPAGLGELG 84
G A P E PP PA GA P P P GP PG G G
Sbjct: 887 GTAGGPGLKGNEGPSGPPGPAGSPGERGAAGSGGPIGPPGRPGPQGP--PGAAGEKGVPG 944
Query: 85 E--PAGPGEPEGPGDPAAAPAEAEEQAVEARQEEEQDLDGEKG----PSSEGPEEEDGE 137
E P GP +G P P A V DG+KG P +G + GE
Sbjct: 945 EKGPIGPTGRDGVQGPVGLPGPAGPPGVAGE-------DGDKGEVGDPGQKGTKGNKGE 996
Score = 37.7 bits (86), Expect = 0.007
Identities = 34/122 (27%), Positives = 41/122 (33%), Gaps = 12/122 (9%)
Query: 29 RGAAASPEPARAPPEPAPPAEA--TGAPAPSRPCAPEPAASPAGPEEPGEPAGLGELGEP 86
RG + P EP PP TG P P P P P PGE G+ G
Sbjct: 1126 RGERGEKGESGQPGEPGPPGPKGPTGDDGPKGN--PGPVGFPGDPGPPGEGGPRGQDGAK 1183
Query: 87 AGPGEPEGPGDPAAAPAEAEEQAVEARQEEEQDLDGEKGPSSEGPEEEDGEGFSFKYSPG 146
GE PG P +P E G++GP+ E G K PG
Sbjct: 1184 GDRGEDGEPGQP-GSPGPTGENGPPGPL-------GKRGPAGSPGSEGRQGGKGAKGDPG 1235
Query: 147 KL 148
+
Sbjct: 1236 AI 1237
Score = 37.4 bits (85), Expect = 0.009
Identities = 38/121 (31%), Positives = 44/121 (36%), Gaps = 31/121 (25%)
Query: 28 RRGAAASPEPARAPPEPAP------PAE-----ATGAPAPSRPCAPEPAASPAG-PEEPG 75
+ G P P AP + P P E G P P PAG P E G
Sbjct: 855 KEGTKGDPGPPGAPGKDGPAGLRGFPGERGLPGTAGGPGLKGNEGPSGPPGPAGSPGERG 914
Query: 76 EPAGLGELGEPAGPGEPEGPGDPAAAPAEAEEQAVEARQEEEQDLDGEKGPSSEGPEEED 135
G +G P PG P+GP P AA E+ + GEKGP GP D
Sbjct: 915 AAGSGGPIGPPGRPG-PQGP--PGAA--------------GEKGVPGEKGPI--GPTGRD 955
Query: 136 G 136
G
Sbjct: 956 G 956
Score = 37.0 bits (84), Expect = 0.012
Identities = 44/151 (29%), Positives = 50/151 (33%), Gaps = 43/151 (28%)
Query: 29 RGAAASPEPARAPPEPAPP-----AEATGAPAPSRPCAP---EPAASPAGPEEPGEPAGL 80
RGAA S P P P P A G P P P + P G P P G+
Sbjct: 913 RGAAGSGGPIGPPGRPGPQGPPGAAGEKGVPGEKGPIGPTGRDGVQGPVGLPGPAGPPGV 972
Query: 81 ----------------------GELGEPAGPGEPEGP-GDPAAAPAEAEEQAVEAR---- 113
GE G P PG P GP G P AA A+ E A +
Sbjct: 973 AGEDGDKGEVGDPGQKGTKGNKGEHGPPGPPG-PIGPVGQPGAAGADGEPGARGPQGHFG 1031
Query: 114 ---QEEEQDLDGEKGP----SSEGPEEEDGE 137
E + +G GP GP E GE
Sbjct: 1032 AKGDEGTRGFNGPPGPIGLQGLPGPSGEKGE 1062
Score = 36.2 bits (82), Expect = 0.020
Identities = 40/142 (28%), Positives = 52/142 (36%), Gaps = 21/142 (14%)
Query: 26 LVRRGAAASP--EPARAPPEPAPPAEATGAPAPSRPCAPEPAASPAGPE----------E 73
L +RG A SP E + A GAP + P P A GP+ +
Sbjct: 1210 LGKRGPAGSPGSEGRQGGKGAKGDPGAIGAPGKTGPVGPAGPAGKPGPDGLRGLPGSVGQ 1269
Query: 74 PGEPAGLGELGEPAGPGEPEGPGDPAAAPAEAEEQAVE----ARQEEEQDLDGEKG-PSS 128
G P G+ G P G P PG A A+ E+ EQ G++G P
Sbjct: 1270 QGRPGATGQAGPPGPVGPPGLPGLRGDAGAKGEKGHPGLIGLIGPPGEQGEKGDRGLPGP 1329
Query: 129 EGPEEEDGE----GFSFKYSPG 146
+G + GE G S PG
Sbjct: 1330 QGSPGQKGEMGIPGASGPIGPG 1351
Score = 35.4 bits (80), Expect = 0.034
Identities = 31/102 (30%), Positives = 37/102 (36%), Gaps = 29/102 (28%)
Query: 30 GAAASPEPARAPPEPAPPAEA-----TGAPA-------PSRPCAPEPAA----------- 66
G +P P P +P PP E GA P +P +P P
Sbjct: 1154 GPKGNPGPVGFPGDPGPPGEGGPRGQDGAKGDRGEDGEPGQPGSPGPTGENGPPGPLGKR 1213
Query: 67 SPAG-PEEPGEPAGLGELGEP---AGPGE--PEGPGDPAAAP 102
PAG P G G G G+P PG+ P GP PA P
Sbjct: 1214 GPAGSPGSEGRQGGKGAKGDPGAIGAPGKTGPVGPAGPAGKP 1255
Score = 35.0 bits (79), Expect = 0.044
Identities = 29/103 (28%), Positives = 35/103 (33%), Gaps = 22/103 (21%)
Query: 43 EPAPPAE-----ATGAPAPSRPCAPEPAASPAGPEEPGEPAGLGELGEPAGPGE------ 91
EP PP + G P P P P G +PG P G G P PG+
Sbjct: 537 EPGPPGQQGTPGTQGLPGPQGAIGPHGEKGPQG--KPGLPGMPGSDGPPGHPGKEGPPGT 594
Query: 92 -----PEGPGDPAAAPAEAEEQAVEARQEEEQDLDGEKGPSSE 129
P GP P P + V+ + L G KG E
Sbjct: 595 KGNQGPSGPQGPLGYPGPRGVKGVDG----IRGLKGHKGEKGE 633
Score = 35.0 bits (79), Expect = 0.044
Identities = 25/81 (30%), Positives = 28/81 (34%), Gaps = 13/81 (16%)
Query: 29 RGAAASPEPARAPPEPAPPAEA-----TGAPAPSRPCAPEPAASPAGPEEPGEPAGLGEL 83
+G P P P E TG P P P+ AA GP +GE
Sbjct: 784 KGPPGPPGKDGLPGHPGQRGEVGFQGKTGPPGPPGVVGPQGAAGETGP--------MGER 835
Query: 84 GEPAGPGEPEGPGDPAAAPAE 104
G P PG P G P A E
Sbjct: 836 GHPGPPGPPGEQGLPGTAGKE 856
Score = 35.0 bits (79), Expect = 0.044
Identities = 36/109 (33%), Positives = 42/109 (38%), Gaps = 14/109 (12%)
Query: 30 GAAASPEPARAPPEPAPPAEATGAPAPSRPCAPEPAASPAGPEEPGEPAGL-GELGEPAG 88
G + SP P P E +P P P P GP P G G +G P
Sbjct: 1109 GESGSPGIQGEPGVKGPRGERGEKGESGQPGEPGPPG-PKGPTGDDGPKGNPGPVGFPGD 1167
Query: 89 PGEPEGPGDPAAAPAEAEEQAVEARQEEEQDLDGEKG-PSSEGPEEEDG 136
PG P G G P ++ A R E DGE G P S GP E+G
Sbjct: 1168 PG-PPGEGGP-----RGQDGAKGDRGE-----DGEPGQPGSPGPTGENG 1205
Score = 34.3 bits (77), Expect = 0.075
Identities = 37/121 (30%), Positives = 42/121 (34%), Gaps = 12/121 (9%)
Query: 35 PEPARAPPEPAPPAEATGAPAPSRPCAPEPAASPAGPEEPGEPAGLGELGEPAGPGEPEG 94
P R P P P G P P P P P P PG+ +G G+ PG P
Sbjct: 765 PPGERGLPGPQGP---NGFPGPKGP--PGPPGKDGLPGHPGQRGEVGFQGKTGPPGPPGV 819
Query: 95 PGDPAAA----PAEAEEQAVEARQEEEQDLDGEKGPSSEGPEEEDG-EGFSFKYSPGKLR 149
G AA P EQ L G G EG + + G G K P LR
Sbjct: 820 VGPQGAAGETGPMGERGHPGPPGPPGEQGLPGTAG--KEGTKGDPGPPGAPGKDGPAGLR 877
Query: 150 G 150
G
Sbjct: 878 G 878
Score = 33.9 bits (76), Expect = 0.098
Identities = 23/76 (30%), Positives = 27/76 (35%), Gaps = 7/76 (9%)
Query: 28 RRGAAASPEPARAPPEPAPPAEATGAP-----APSRPCAPEPAASPAGPEEPGEPAGLGE 82
+R P P P ++A P P EP GP P PAGL
Sbjct: 245 QRSPQQQPSRLHRPQNQEPQSQAAHGPRGLKGEKGEPAVLEPGMLVEGPPGPEGPAGL-- 302
Query: 83 LGEPAGPGEPEGPGDP 98
+G P G P GDP
Sbjct: 303 IGPPGIQGNPGPVGDP 318
Score = 33.5 bits (75), Expect = 0.13
Identities = 33/117 (28%), Positives = 39/117 (33%), Gaps = 29/117 (24%)
Query: 29 RGAAASPEPA---RAPPEPAPPAEATGAPAPSRPCAPEPAASPAGPEEPGEPAGLGELGE 85
+G A EP PP P PA G P +P +PGE G G
Sbjct: 278 KGEPAVLEPGMLVEGPPGPEGPAGLIGPPGIQ--------GNPGPVGDPGERGPPGRAGL 329
Query: 86 PAGPGEPEGPG----------------DPAAAPAEAEEQAVEARQEEEQDLDGEKGP 126
P G P PG P A EA+ QA+ Q+ L G GP
Sbjct: 330 PGSDGAPGPPGTSLMLPFRFGSGGGDKGPVVAAQEAQAQAI--LQQARLALRGPPGP 384
Score = 32.3 bits (72), Expect = 0.29
Identities = 32/97 (32%), Positives = 39/97 (40%), Gaps = 19/97 (19%)
Query: 52 GAPAPSRPCAPEPAASPAGPE-EPGEPAGLGE---LGEPAGPGEP--EGP----GDPAAA 101
G P PE GP +PG P +GE LG P PG P +GP G P
Sbjct: 653 GVPGSRGEDGPEGPKGRTGPTGDPGPPGLMGEKGKLGVPGLPGYPGRQGPKGSLGFPGFP 712
Query: 102 PAEAEEQAVEARQEEEQDLDGEKGPSSE-GPEEEDGE 137
A E+ A + L G+ GP E GP G+
Sbjct: 713 GASGEKGA--------RGLSGKSGPRGERGPTGPRGQ 741
Score = 31.2 bits (69), Expect = 0.64
Identities = 33/121 (27%), Positives = 44/121 (36%), Gaps = 21/121 (17%)
Query: 29 RGAAASPEPARAPPEPAPPAEATGAPAPSRPC---APEPAASPAGPE------EPGEPAG 79
+G P P +P + G P S P P PAGP+ PG P
Sbjct: 1321 KGDRGLPGPQGSPGQKGE----MGIPGASGPIGPGGPPGLPGPAGPKGAKGATGPGGPK- 1375
Query: 80 LGELGEPAGPGEPEGPGD-----PAAAPAEAEEQAVEAR-QEEEQDLDGEKGPSSEGPEE 133
GE G PG P PG+ P P + +R +E++ + P S G E
Sbjct: 1376 -GEKGVQGPPGHPGPPGEVIQPLPIQMPKKTRRSVDGSRLMQEDEAIPTGGAPGSPGGLE 1434
Query: 134 E 134
E
Sbjct: 1435 E 1435
Score = 30.8 bits (68), Expect = 0.83
Identities = 33/132 (25%), Positives = 42/132 (31%), Gaps = 12/132 (9%)
Query: 30 GAAASPEPARAPPEPAPPAEA--TGAPAPSRPCAPEPAASPAGPEEPGEPAGLGELGEPA 87
GA P P E E G P S P P GP P G+ + P
Sbjct: 470 GAQGLPGPPGEDGERGDDGEIGPRGLPGES---GPRGLLGPKGPPGIPGPPGVRGMDGPQ 526
Query: 88 GPGEPEGPGDPAAAPAEAEEQAVEARQEEEQDL--DGEKGPSSEG-----PEEEDGEGFS 140
GP GP P + + + + GEKGP + P + G
Sbjct: 527 GPKGSLGPQGEPGPPGQQGTPGTQGLPGPQGAIGPHGEKGPQGKPGLPGMPGSDGPPGHP 586
Query: 141 FKYSPGKLRGNQ 152
K P +GNQ
Sbjct: 587 GKEGPPGTKGNQ 598
Score = 29.3 bits (64), Expect = 2.4
Identities = 30/97 (30%), Positives = 33/97 (34%), Gaps = 25/97 (25%)
Query: 62 PEPAASPAGPEEPGEPAGLGELGEPAGPGEPEG-PGDPAAAPAEAEEQAVEARQ------ 114
P P P P GE LG P GP P+G G P A A AR
Sbjct: 391 PGPLGQPGSPGLKGESGDLG----PQGPRGPQGLTGPPGKAGRRGRAGADGARGMPGDPG 446
Query: 115 -------EEEQDLDGEKGPSSE-------GPEEEDGE 137
+ L GEKG + GP EDGE
Sbjct: 447 VKGDRGFDGLPGLPGEKGHRGDTGAQGLPGPPGEDGE 483
Score = 29.3 bits (64), Expect = 2.4
Identities = 27/105 (25%), Positives = 36/105 (34%), Gaps = 15/105 (14%)
Query: 37 PARAPPEPAPPAEA--TGAPAPSRPCAPEPAASPAGPEE-------PGEPAGLGELGEPA 87
P P P PP G P P+ P G + PG +G GE
Sbjct: 507 PKGPPGIPGPPGVRGMDGPQGPKGSLGPQGEPGPPGQQGTPGTQGLPGPQGAIGPHGEKG 566
Query: 88 GPGEPEGPGDPAAAPAEAEEQAVEARQEEEQDLDGEKGPSS-EGP 131
G+P PG P ++ +E G +GPS +GP
Sbjct: 567 PQGKPGLPGMPG-----SDGPPGHPGKEGPPGTKGNQGPSGPQGP 606
Score = 28.5 bits (62), Expect = 4.1
Identities = 25/95 (26%), Positives = 31/95 (32%), Gaps = 5/95 (5%)
Query: 47 PAEATGAPAPSRPCAPEPAASPAGPEEPGEPAGLGELGEPAGPGEPEGPGDPAAAPAEAE 106
P G P A +G + P P G L P GP GP P P + +
Sbjct: 735 PTGPRGQRGPRGATGKSGAKGTSGGDGPHGPPGERGLPGPQGPNGFPGPKGPPGPPGK-D 793
Query: 107 EQAVEARQEEEQDLDGEKGPSSE----GPEEEDGE 137
Q E G+ GP GP+ GE
Sbjct: 794 GLPGHPGQRGEVGFQGKTGPPGPPGVVGPQGAAGE 828
Score = 28.1 bits (61), Expect = 5.4
Identities = 24/83 (28%), Positives = 32/83 (38%), Gaps = 14/83 (16%)
Query: 68 PAGPEEPGEPAGLGELGEPAGPGEPEGPGD-----PAAAPAEAEEQAVEARQEEE----- 117
P P E G G G P PGE GD P P E+ + + +
Sbjct: 457 PGLPGEKGHRGDTGAQGLPGPPGEDGERGDDGEIGPRGLPGESGPRGLLGPKGPPGIPGP 516
Query: 118 ---QDLDGEKGP-SSEGPEEEDG 136
+ +DG +GP S GP+ E G
Sbjct: 517 PGVRGMDGPQGPKGSLGPQGEPG 539
Score = 27.3 bits (59), Expect = 9.2
Identities = 27/102 (26%), Positives = 33/102 (32%), Gaps = 28/102 (27%)
Query: 23 AWLLVRRGAAASPEPARAPPEPAPPAEA-----TGAPAP--SRPCAPEPAASPAGPEEP- 74
A L+ G +P P P E PP A GAP P + P S G + P
Sbjct: 300 AGLIGPPGIQGNPGPVGDPGERGPPGRAGLPGSDGAPGPPGTSLMLPFRFGSGGGDKGPV 359
Query: 75 --------------------GEPAGLGELGEPAGPGEPEGPG 96
G P +G G P G+P PG
Sbjct: 360 VAAQEAQAQAILQQARLALRGPPGPMGYTGRPGPLGQPGSPG 401
>gi|111118970 collagen, type XI, alpha 2 isoform 1 preproprotein [Homo
sapiens]
Length = 1736
Score = 49.7 bits (117), Expect = 2e-06
Identities = 39/116 (33%), Positives = 44/116 (37%), Gaps = 8/116 (6%)
Query: 29 RGAAASPEPARAPPEPAPPAEA--TGAPAPSRPCAPEPAASPAGPE----EPGEPAGLGE 82
RG P P P P E TG P P P PAGP G P G+G
Sbjct: 1146 RGFNGPPGPIGLQGLPGPSGEKGETGDVGPMGPPGPPGPRGPAGPNGADGPQGPPGGVGN 1205
Query: 83 LGEPAGPGEPEGPGDPAAAPAEAEEQAVEARQEE-EQDLDGEKG-PSSEGPEEEDG 136
LG P GEP G P + R E+ E GE G P +GP +DG
Sbjct: 1206 LGPPGEKGEPGESGSPGIQGEPGVKGPRGERGEKGESGQPGEPGPPGPKGPTGDDG 1261
Score = 40.0 bits (92), Expect = 0.001
Identities = 32/110 (29%), Positives = 38/110 (34%), Gaps = 16/110 (14%)
Query: 41 PPEPAPPAEATGAPAPSRPCA-------------PEPAASPAGPEEPGEPAGLGELGEPA 87
PP P PA GA P P P + SP EPG GE GE
Sbjct: 1181 PPGPRGPAGPNGADGPQGPPGGVGNLGPPGEKGEPGESGSPGIQGEPGVKGPRGERGEKG 1240
Query: 88 GPGEPEGPGDPAAAPAEAEEQAVEARQEEEQDLDGEKGPSSE-GPEEEDG 136
G+P PG P ++ G+ GP E GP +DG
Sbjct: 1241 ESGQPGEPGPPGPKGPTGDDG--PKGNPGPVGFPGDPGPPGEGGPRGQDG 1288
Score = 38.5 bits (88), Expect = 0.004
Identities = 36/119 (30%), Positives = 40/119 (33%), Gaps = 20/119 (16%)
Query: 30 GAAASP-----EPARAPPEPAPPAEATGAPAPSRPCAPEPAASPAGPEEPGEPAGLGELG 84
G A P E PP PA GA P P P GP PG G G
Sbjct: 994 GTAGGPGLKGNEGPSGPPGPAGSPGERGAAGSGGPIGPPGRPGPQGP--PGAAGEKGVPG 1051
Query: 85 E--PAGPGEPEGPGDPAAAPAEAEEQAVEARQEEEQDLDGEKG----PSSEGPEEEDGE 137
E P GP +G P P A V DG+KG P +G + GE
Sbjct: 1052 EKGPIGPTGRDGVQGPVGLPGPAGPPGVAGE-------DGDKGEVGDPGQKGTKGNKGE 1103
Score = 37.7 bits (86), Expect = 0.007
Identities = 34/122 (27%), Positives = 41/122 (33%), Gaps = 12/122 (9%)
Query: 29 RGAAASPEPARAPPEPAPPAEA--TGAPAPSRPCAPEPAASPAGPEEPGEPAGLGELGEP 86
RG + P EP PP TG P P P P P PGE G+ G
Sbjct: 1233 RGERGEKGESGQPGEPGPPGPKGPTGDDGPKGN--PGPVGFPGDPGPPGEGGPRGQDGAK 1290
Query: 87 AGPGEPEGPGDPAAAPAEAEEQAVEARQEEEQDLDGEKGPSSEGPEEEDGEGFSFKYSPG 146
GE PG P +P E G++GP+ E G K PG
Sbjct: 1291 GDRGEDGEPGQP-GSPGPTGENGPPGPL-------GKRGPAGSPGSEGRQGGKGAKGDPG 1342
Query: 147 KL 148
+
Sbjct: 1343 AI 1344
Score = 37.4 bits (85), Expect = 0.009
Identities = 38/121 (31%), Positives = 44/121 (36%), Gaps = 31/121 (25%)
Query: 28 RRGAAASPEPARAPPEPAP------PAE-----ATGAPAPSRPCAPEPAASPAG-PEEPG 75
+ G P P AP + P P E G P P PAG P E G
Sbjct: 962 KEGTKGDPGPPGAPGKDGPAGLRGFPGERGLPGTAGGPGLKGNEGPSGPPGPAGSPGERG 1021
Query: 76 EPAGLGELGEPAGPGEPEGPGDPAAAPAEAEEQAVEARQEEEQDLDGEKGPSSEGPEEED 135
G +G P PG P+GP P AA E+ + GEKGP GP D
Sbjct: 1022 AAGSGGPIGPPGRPG-PQGP--PGAA--------------GEKGVPGEKGPI--GPTGRD 1062
Query: 136 G 136
G
Sbjct: 1063 G 1063
Score = 37.0 bits (84), Expect = 0.012
Identities = 44/151 (29%), Positives = 50/151 (33%), Gaps = 43/151 (28%)
Query: 29 RGAAASPEPARAPPEPAPP-----AEATGAPAPSRPCAP---EPAASPAGPEEPGEPAGL 80
RGAA S P P P P A G P P P + P G P P G+
Sbjct: 1020 RGAAGSGGPIGPPGRPGPQGPPGAAGEKGVPGEKGPIGPTGRDGVQGPVGLPGPAGPPGV 1079
Query: 81 ----------------------GELGEPAGPGEPEGP-GDPAAAPAEAEEQAVEAR---- 113
GE G P PG P GP G P AA A+ E A +
Sbjct: 1080 AGEDGDKGEVGDPGQKGTKGNKGEHGPPGPPG-PIGPVGQPGAAGADGEPGARGPQGHFG 1138
Query: 114 ---QEEEQDLDGEKGP----SSEGPEEEDGE 137
E + +G GP GP E GE
Sbjct: 1139 AKGDEGTRGFNGPPGPIGLQGLPGPSGEKGE 1169
Score = 36.2 bits (82), Expect = 0.020
Identities = 40/142 (28%), Positives = 52/142 (36%), Gaps = 21/142 (14%)
Query: 26 LVRRGAAASP--EPARAPPEPAPPAEATGAPAPSRPCAPEPAASPAGPE----------E 73
L +RG A SP E + A GAP + P P A GP+ +
Sbjct: 1317 LGKRGPAGSPGSEGRQGGKGAKGDPGAIGAPGKTGPVGPAGPAGKPGPDGLRGLPGSVGQ 1376
Query: 74 PGEPAGLGELGEPAGPGEPEGPGDPAAAPAEAEEQAVE----ARQEEEQDLDGEKG-PSS 128
G P G+ G P G P PG A A+ E+ EQ G++G P
Sbjct: 1377 QGRPGATGQAGPPGPVGPPGLPGLRGDAGAKGEKGHPGLIGLIGPPGEQGEKGDRGLPGP 1436
Query: 129 EGPEEEDGE----GFSFKYSPG 146
+G + GE G S PG
Sbjct: 1437 QGSPGQKGEMGIPGASGPIGPG 1458
Score = 35.4 bits (80), Expect = 0.034
Identities = 31/102 (30%), Positives = 37/102 (36%), Gaps = 29/102 (28%)
Query: 30 GAAASPEPARAPPEPAPPAEA-----TGAPA-------PSRPCAPEPAA----------- 66
G +P P P +P PP E GA P +P +P P
Sbjct: 1261 GPKGNPGPVGFPGDPGPPGEGGPRGQDGAKGDRGEDGEPGQPGSPGPTGENGPPGPLGKR 1320
Query: 67 SPAG-PEEPGEPAGLGELGEP---AGPGE--PEGPGDPAAAP 102
PAG P G G G G+P PG+ P GP PA P
Sbjct: 1321 GPAGSPGSEGRQGGKGAKGDPGAIGAPGKTGPVGPAGPAGKP 1362
Score = 35.0 bits (79), Expect = 0.044
Identities = 29/103 (28%), Positives = 35/103 (33%), Gaps = 22/103 (21%)
Query: 43 EPAPPAE-----ATGAPAPSRPCAPEPAASPAGPEEPGEPAGLGELGEPAGPGE------ 91
EP PP + G P P P P G +PG P G G P PG+
Sbjct: 644 EPGPPGQQGTPGTQGLPGPQGAIGPHGEKGPQG--KPGLPGMPGSDGPPGHPGKEGPPGT 701
Query: 92 -----PEGPGDPAAAPAEAEEQAVEARQEEEQDLDGEKGPSSE 129
P GP P P + V+ + L G KG E
Sbjct: 702 KGNQGPSGPQGPLGYPGPRGVKGVDG----IRGLKGHKGEKGE 740
Score = 35.0 bits (79), Expect = 0.044
Identities = 25/81 (30%), Positives = 28/81 (34%), Gaps = 13/81 (16%)
Query: 29 RGAAASPEPARAPPEPAPPAEA-----TGAPAPSRPCAPEPAASPAGPEEPGEPAGLGEL 83
+G P P P E TG P P P+ AA GP +GE
Sbjct: 891 KGPPGPPGKDGLPGHPGQRGEVGFQGKTGPPGPPGVVGPQGAAGETGP--------MGER 942
Query: 84 GEPAGPGEPEGPGDPAAAPAE 104
G P PG P G P A E
Sbjct: 943 GHPGPPGPPGEQGLPGTAGKE 963
Score = 35.0 bits (79), Expect = 0.044
Identities = 36/109 (33%), Positives = 42/109 (38%), Gaps = 14/109 (12%)
Query: 30 GAAASPEPARAPPEPAPPAEATGAPAPSRPCAPEPAASPAGPEEPGEPAGL-GELGEPAG 88
G + SP P P E +P P P P GP P G G +G P
Sbjct: 1216 GESGSPGIQGEPGVKGPRGERGEKGESGQPGEPGPPG-PKGPTGDDGPKGNPGPVGFPGD 1274
Query: 89 PGEPEGPGDPAAAPAEAEEQAVEARQEEEQDLDGEKG-PSSEGPEEEDG 136
PG P G G P ++ A R E DGE G P S GP E+G
Sbjct: 1275 PG-PPGEGGP-----RGQDGAKGDRGE-----DGEPGQPGSPGPTGENG 1312
Score = 34.3 bits (77), Expect = 0.075
Identities = 37/121 (30%), Positives = 42/121 (34%), Gaps = 12/121 (9%)
Query: 35 PEPARAPPEPAPPAEATGAPAPSRPCAPEPAASPAGPEEPGEPAGLGELGEPAGPGEPEG 94
P R P P P G P P P P P P PG+ +G G+ PG P
Sbjct: 872 PPGERGLPGPQGP---NGFPGPKGP--PGPPGKDGLPGHPGQRGEVGFQGKTGPPGPPGV 926
Query: 95 PGDPAAA----PAEAEEQAVEARQEEEQDLDGEKGPSSEGPEEEDG-EGFSFKYSPGKLR 149
G AA P EQ L G G EG + + G G K P LR
Sbjct: 927 VGPQGAAGETGPMGERGHPGPPGPPGEQGLPGTAG--KEGTKGDPGPPGAPGKDGPAGLR 984
Query: 150 G 150
G
Sbjct: 985 G 985
Score = 33.5 bits (75), Expect = 0.13
Identities = 33/117 (28%), Positives = 39/117 (33%), Gaps = 29/117 (24%)
Query: 29 RGAAASPEPA---RAPPEPAPPAEATGAPAPSRPCAPEPAASPAGPEEPGEPAGLGELGE 85
+G A EP PP P PA G P +P +PGE G G
Sbjct: 385 KGEPAVLEPGMLVEGPPGPEGPAGLIGPPGIQ--------GNPGPVGDPGERGPPGRAGL 436
Query: 86 PAGPGEPEGPG----------------DPAAAPAEAEEQAVEARQEEEQDLDGEKGP 126
P G P PG P A EA+ QA+ Q+ L G GP
Sbjct: 437 PGSDGAPGPPGTSLMLPFRFGSGGGDKGPVVAAQEAQAQAI--LQQARLALRGPPGP 491
Score = 32.3 bits (72), Expect = 0.29
Identities = 32/97 (32%), Positives = 39/97 (40%), Gaps = 19/97 (19%)
Query: 52 GAPAPSRPCAPEPAASPAGPE-EPGEPAGLGE---LGEPAGPGEP--EGP----GDPAAA 101
G P PE GP +PG P +GE LG P PG P +GP G P
Sbjct: 760 GVPGSRGEDGPEGPKGRTGPTGDPGPPGLMGEKGKLGVPGLPGYPGRQGPKGSLGFPGFP 819
Query: 102 PAEAEEQAVEARQEEEQDLDGEKGPSSE-GPEEEDGE 137
A E+ A + L G+ GP E GP G+
Sbjct: 820 GASGEKGA--------RGLSGKSGPRGERGPTGPRGQ 848
Score = 31.2 bits (69), Expect = 0.64
Identities = 33/121 (27%), Positives = 44/121 (36%), Gaps = 21/121 (17%)
Query: 29 RGAAASPEPARAPPEPAPPAEATGAPAPSRPC---APEPAASPAGPE------EPGEPAG 79
+G P P +P + G P S P P PAGP+ PG P
Sbjct: 1428 KGDRGLPGPQGSPGQKGE----MGIPGASGPIGPGGPPGLPGPAGPKGAKGATGPGGPK- 1482
Query: 80 LGELGEPAGPGEPEGPGD-----PAAAPAEAEEQAVEAR-QEEEQDLDGEKGPSSEGPEE 133
GE G PG P PG+ P P + +R +E++ + P S G E
Sbjct: 1483 -GEKGVQGPPGHPGPPGEVIQPLPIQMPKKTRRSVDGSRLMQEDEAIPTGGAPGSPGGLE 1541
Query: 134 E 134
E
Sbjct: 1542 E 1542
Score = 30.8 bits (68), Expect = 0.83
Identities = 33/132 (25%), Positives = 42/132 (31%), Gaps = 12/132 (9%)
Query: 30 GAAASPEPARAPPEPAPPAEA--TGAPAPSRPCAPEPAASPAGPEEPGEPAGLGELGEPA 87
GA P P E E G P S P P GP P G+ + P
Sbjct: 577 GAQGLPGPPGEDGERGDDGEIGPRGLPGES---GPRGLLGPKGPPGIPGPPGVRGMDGPQ 633
Query: 88 GPGEPEGPGDPAAAPAEAEEQAVEARQEEEQDL--DGEKGPSSEG-----PEEEDGEGFS 140
GP GP P + + + + GEKGP + P + G
Sbjct: 634 GPKGSLGPQGEPGPPGQQGTPGTQGLPGPQGAIGPHGEKGPQGKPGLPGMPGSDGPPGHP 693
Query: 141 FKYSPGKLRGNQ 152
K P +GNQ
Sbjct: 694 GKEGPPGTKGNQ 705
Score = 29.3 bits (64), Expect = 2.4
Identities = 30/97 (30%), Positives = 33/97 (34%), Gaps = 25/97 (25%)
Query: 62 PEPAASPAGPEEPGEPAGLGELGEPAGPGEPEG-PGDPAAAPAEAEEQAVEARQ------ 114
P P P P GE LG P GP P+G G P A A AR
Sbjct: 498 PGPLGQPGSPGLKGESGDLG----PQGPRGPQGLTGPPGKAGRRGRAGADGARGMPGDPG 553
Query: 115 -------EEEQDLDGEKGPSSE-------GPEEEDGE 137
+ L GEKG + GP EDGE
Sbjct: 554 VKGDRGFDGLPGLPGEKGHRGDTGAQGLPGPPGEDGE 590
Score = 29.3 bits (64), Expect = 2.4
Identities = 27/105 (25%), Positives = 36/105 (34%), Gaps = 15/105 (14%)
Query: 37 PARAPPEPAPPAEA--TGAPAPSRPCAPEPAASPAGPEE-------PGEPAGLGELGEPA 87
P P P PP G P P+ P G + PG +G GE
Sbjct: 614 PKGPPGIPGPPGVRGMDGPQGPKGSLGPQGEPGPPGQQGTPGTQGLPGPQGAIGPHGEKG 673
Query: 88 GPGEPEGPGDPAAAPAEAEEQAVEARQEEEQDLDGEKGPSS-EGP 131
G+P PG P ++ +E G +GPS +GP
Sbjct: 674 PQGKPGLPGMPG-----SDGPPGHPGKEGPPGTKGNQGPSGPQGP 713
Score = 28.5 bits (62), Expect = 4.1
Identities = 22/70 (31%), Positives = 25/70 (35%), Gaps = 1/70 (1%)
Query: 32 AASPEPARAPPEPAPPAEATGAPAPSRPCAPEPAASPAGPEE-PGEPAGLGELGEPAGPG 90
AA+ P E PA P PE A GP G P +G+ GE PG
Sbjct: 373 AAAHGPRGLKGEKGEPAVLEPGMLVEGPPGPEGPAGLIGPPGIQGNPGPVGDPGERGPPG 432
Query: 91 EPEGPGDPAA 100
PG A
Sbjct: 433 RAGLPGSDGA 442
Score = 28.5 bits (62), Expect = 4.1
Identities = 25/95 (26%), Positives = 31/95 (32%), Gaps = 5/95 (5%)
Query: 47 PAEATGAPAPSRPCAPEPAASPAGPEEPGEPAGLGELGEPAGPGEPEGPGDPAAAPAEAE 106
P G P A +G + P P G L P GP GP P P + +
Sbjct: 842 PTGPRGQRGPRGATGKSGAKGTSGGDGPHGPPGERGLPGPQGPNGFPGPKGPPGPPGK-D 900
Query: 107 EQAVEARQEEEQDLDGEKGPSSE----GPEEEDGE 137
Q E G+ GP GP+ GE
Sbjct: 901 GLPGHPGQRGEVGFQGKTGPPGPPGVVGPQGAAGE 935
Score = 28.1 bits (61), Expect = 5.4
Identities = 24/83 (28%), Positives = 32/83 (38%), Gaps = 14/83 (16%)
Query: 68 PAGPEEPGEPAGLGELGEPAGPGEPEGPGD-----PAAAPAEAEEQAVEARQEEE----- 117
P P E G G G P PGE GD P P E+ + + +
Sbjct: 564 PGLPGEKGHRGDTGAQGLPGPPGEDGERGDDGEIGPRGLPGESGPRGLLGPKGPPGIPGP 623
Query: 118 ---QDLDGEKGP-SSEGPEEEDG 136
+ +DG +GP S GP+ E G
Sbjct: 624 PGVRGMDGPQGPKGSLGPQGEPG 646
Score = 27.3 bits (59), Expect = 9.2
Identities = 27/102 (26%), Positives = 33/102 (32%), Gaps = 28/102 (27%)
Query: 23 AWLLVRRGAAASPEPARAPPEPAPPAEA-----TGAPAP--SRPCAPEPAASPAGPEEP- 74
A L+ G +P P P E PP A GAP P + P S G + P
Sbjct: 407 AGLIGPPGIQGNPGPVGDPGERGPPGRAGLPGSDGAPGPPGTSLMLPFRFGSGGGDKGPV 466
Query: 75 --------------------GEPAGLGELGEPAGPGEPEGPG 96
G P +G G P G+P PG
Sbjct: 467 VAAQEAQAQAILQQARLALRGPPGPMGYTGRPGPLGQPGSPG 508
>gi|194578898 hypothetical protein LOC100170841 [Homo sapiens]
Length = 379
Score = 49.3 bits (116), Expect = 2e-06
Identities = 41/129 (31%), Positives = 54/129 (41%), Gaps = 32/129 (24%)
Query: 38 ARAPPEPAPPAEATGAPAPSRPCAPEPAASPAGPEEPGEPAGLGELGEPAGPG---EPEG 94
A APP PAP E PA S P EP++ P P PAGL EPAGPG P
Sbjct: 154 ASAPPRPAPGLEPQRGPAASPP--QEPSSRP-----PSPPAGLST--EPAGPGTAPRPFL 204
Query: 95 PGDPAAAPAEAEEQAVEARQEEEQDLDGEKGPSS-EGPEEEDGEGFSFKYSPGKLRGNQY 153
PG PA ++DG P++ E P +PG LR +
Sbjct: 205 PGQPA-------------------EVDGNPPPAAPEAPAASPSTASPAPAAPGDLRQEHF 245
Query: 154 KKMMTKEEL 162
+++ + +L
Sbjct: 246 DRLIRRSKL 254
Score = 37.4 bits (85), Expect = 0.009
Identities = 24/72 (33%), Positives = 31/72 (43%), Gaps = 8/72 (11%)
Query: 36 EPARAPPEPAPPAEATGAPAPSRPCAPEPAASPAGPEE--PGEPAGLGELGEPAGPGEPE 93
EP R P P ++ P+P + EPA P PG+PA E G P
Sbjct: 165 EPQRGPAASPPQEPSSRPPSPPAGLSTEPAGPGTAPRPFLPGQPA------EVDGNPPPA 218
Query: 94 GPGDPAAAPAEA 105
P PAA+P+ A
Sbjct: 219 APEAPAASPSTA 230
Score = 37.0 bits (84), Expect = 0.012
Identities = 26/82 (31%), Positives = 34/82 (41%), Gaps = 6/82 (7%)
Query: 28 RRGAAASPEPARAPPEPAPPAEATGAPAPSRPCAPEPAASPAGPEEPGEPAGLGELGEPA 87
+RG AASP + P+PPA + PA P A P P +P E G P
Sbjct: 167 QRGPAASPPQEPSSRPPSPPAGLSTEPA-----GPGTAPRPFLPGQPAEVDGNPPPAAPE 221
Query: 88 GPGEPEGPGDPA-AAPAEAEEQ 108
P PA AAP + ++
Sbjct: 222 APAASPSTASPAPAAPGDLRQE 243
Score = 28.5 bits (62), Expect = 4.1
Identities = 33/120 (27%), Positives = 41/120 (34%), Gaps = 35/120 (29%)
Query: 37 PARAPPEPAPPAEATGAPAPSRPC------------------APEPAASPAGPEEPGEPA 78
PA PA P + +P P +PC +P AS GP PGE A
Sbjct: 6 PAPRLAVPASPRGSPCSPTPRKPCRGTQEFSPLCLRALAFCALAKPRASSLGP-GPGELA 64
Query: 79 GLGE-LGEPAGPGEPEG---------------PGDPAAAPAEAEEQAVEARQEEEQDLDG 122
L P P P G PG P A E + A R+ EE++ G
Sbjct: 65 ARSPVLRGPQAPLRPGGWAPDGLKHLWAPTGRPGVPNTAAGEDADVAACPRRGEEEEGGG 124
>gi|85815829 SH3-domain binding protein 1 [Homo sapiens]
Length = 701
Score = 49.3 bits (116), Expect = 2e-06
Identities = 46/142 (32%), Positives = 57/142 (40%), Gaps = 14/142 (9%)
Query: 3 APAELLAALPALATALALLLAWLLVRRGAAASPEPARAPPEPAPPAE----ATGAPAPSR 58
APA A PALA+A V ASP+ R+PPE A P E T PAP+R
Sbjct: 514 APAPAPAPAPALASAATKERTESEVPP-RPASPKVTRSPPETAAPVEDMARRTKRPAPAR 572
Query: 59 PCAPEP--AASPAGPEEPGEPAGLGELGEP-AGPGEPEGPG------DPAAAPAEAEEQA 109
P P P + S + P P P G G G P A P G P P +
Sbjct: 573 PTMPPPQVSGSRSSPPAPPLPPGSGSPGTPQALPRRLVGSSLRAPTVPPPLPPTPPQPAR 632
Query: 110 VEARQEEEQDLDGEKGPSSEGP 131
++R+ GP+S P
Sbjct: 633 RQSRRSPASPSPASPGPASPSP 654
Score = 32.3 bits (72), Expect = 0.29
Identities = 25/78 (32%), Positives = 32/78 (41%), Gaps = 10/78 (12%)
Query: 32 AASPEPARAPPEPAPPAEATGAPAPSRPCAPEPAASPAGPEEPGEPAGLGELGEPAGPGE 91
A+ P+ A P PA T APAP+ AP PA + A +E E P P
Sbjct: 495 ASEELPSTAVPTPA----TTPAPAPAPAPAPAPALASAATKERTESE------VPPRPAS 544
Query: 92 PEGPGDPAAAPAEAEEQA 109
P+ P A E+ A
Sbjct: 545 PKVTRSPPETAAPVEDMA 562
Score = 32.0 bits (71), Expect = 0.37
Identities = 23/81 (28%), Positives = 27/81 (33%), Gaps = 4/81 (4%)
Query: 26 LVRRGAAASPEPARAPPEPAPPAEATGAPAPSRPCAPEPAASPAGPEEPGEPAGLGELGE 85
LV A P PP P PA +P+ P P + P PA +
Sbjct: 609 LVGSSLRAPTVPPPLPPTPPQPARRQSRRSPASPSPASPGPASPSPVSLSNPAQVDLGAA 668
Query: 86 PAGPGEPEG----PGDPAAAP 102
A G PE P PA P
Sbjct: 669 TAEGGAPEAISGVPTPPAIPP 689
Score = 29.3 bits (64), Expect = 2.4
Identities = 26/100 (26%), Positives = 38/100 (38%), Gaps = 3/100 (3%)
Query: 12 PALATALALLLAWLLVRRGAAASPEPARAPPEPAPPAEATGAPAPSRPCAPEPAA-SPAG 70
P AL L +R P P PP+PA ++ +PA P +P PA+ SP
Sbjct: 599 PGTPQALPRRLVGSSLRAPTVPPPLPP-TPPQPA-RRQSRRSPASPSPASPGPASPSPVS 656
Query: 71 PEEPGEPAGLGELGEPAGPGEPEGPGDPAAAPAEAEEQAV 110
P + E P G P A P + +++
Sbjct: 657 LSNPAQVDLGAATAEGGAPEAISGVPTPPAIPPQPRPRSL 696
>gi|169790903 cyclin-dependent kinase inhibitor 1C isoform b [Homo
sapiens]
Length = 305
Score = 48.9 bits (115), Expect = 3e-06
Identities = 39/129 (30%), Positives = 47/129 (36%), Gaps = 8/129 (6%)
Query: 35 PEPARAP---PEPAPPAEATGAPAPSRPCAPEPAASPAGPEEPGEPAGLGELGEPAGPGE 91
P P AP P PAP A AP AP PA +PA P A PA
Sbjct: 139 PVPVLAPAPAPAPAPVAAPVAAPVAVAVLAPAPAPAPAPAPAPAPVAAPAPAPAPAPAPA 198
Query: 92 PEGPGDPAAAPAEAEEQAVEARQEEEQDL-----DGEKGPSSEGPEEEDGEGFSFKYSPG 146
P P AAP E+ EQ Q ++ L G G + G G + K G
Sbjct: 199 PAPAPAPDAAPQESAEQGANQGQRGQEPLADQLHSGISGRPAAGTAAASANGAAIKKLSG 258
Query: 147 KLRGNQYKK 155
L + + K
Sbjct: 259 PLISDFFAK 267
Score = 43.5 bits (101), Expect = 1e-04
Identities = 42/110 (38%), Positives = 51/110 (46%), Gaps = 10/110 (9%)
Query: 4 PAELLAALPALATA-----LALLLAWLLVRRGAAASPEPARAPPEPAPPAEATG-APAPS 57
P +LA PA A A +A +A ++ A +P PA AP A PA A APAP+
Sbjct: 139 PVPVLAPAPAPAPAPVAAPVAAPVAVAVLAPAPAPAPAPAPAPAPVAAPAPAPAPAPAPA 198
Query: 58 RPCAPEPAASPAGPEEPGEPAGLGELG-EPAGPGEPEG-PGDPAAAPAEA 105
AP P A+P E G A G+ G EP G G PAA A A
Sbjct: 199 PAPAPAPDAAPQESAEQG--ANQGQRGQEPLADQLHSGISGRPAAGTAAA 246
>gi|169790899 cyclin-dependent kinase inhibitor 1C isoform b [Homo
sapiens]
Length = 305
Score = 48.9 bits (115), Expect = 3e-06
Identities = 39/129 (30%), Positives = 47/129 (36%), Gaps = 8/129 (6%)
Query: 35 PEPARAP---PEPAPPAEATGAPAPSRPCAPEPAASPAGPEEPGEPAGLGELGEPAGPGE 91
P P AP P PAP A AP AP PA +PA P A PA
Sbjct: 139 PVPVLAPAPAPAPAPVAAPVAAPVAVAVLAPAPAPAPAPAPAPAPVAAPAPAPAPAPAPA 198
Query: 92 PEGPGDPAAAPAEAEEQAVEARQEEEQDL-----DGEKGPSSEGPEEEDGEGFSFKYSPG 146
P P AAP E+ EQ Q ++ L G G + G G + K G
Sbjct: 199 PAPAPAPDAAPQESAEQGANQGQRGQEPLADQLHSGISGRPAAGTAAASANGAAIKKLSG 258
Query: 147 KLRGNQYKK 155
L + + K
Sbjct: 259 PLISDFFAK 267
Score = 43.5 bits (101), Expect = 1e-04
Identities = 42/110 (38%), Positives = 51/110 (46%), Gaps = 10/110 (9%)
Query: 4 PAELLAALPALATA-----LALLLAWLLVRRGAAASPEPARAPPEPAPPAEATG-APAPS 57
P +LA PA A A +A +A ++ A +P PA AP A PA A APAP+
Sbjct: 139 PVPVLAPAPAPAPAPVAAPVAAPVAVAVLAPAPAPAPAPAPAPAPVAAPAPAPAPAPAPA 198
Query: 58 RPCAPEPAASPAGPEEPGEPAGLGELG-EPAGPGEPEG-PGDPAAAPAEA 105
AP P A+P E G A G+ G EP G G PAA A A
Sbjct: 199 PAPAPAPDAAPQESAEQG--ANQGQRGQEPLADQLHSGISGRPAAGTAAA 246
>gi|4557441 cyclin-dependent kinase inhibitor 1C isoform a [Homo
sapiens]
Length = 316
Score = 48.9 bits (115), Expect = 3e-06
Identities = 39/129 (30%), Positives = 47/129 (36%), Gaps = 8/129 (6%)
Query: 35 PEPARAP---PEPAPPAEATGAPAPSRPCAPEPAASPAGPEEPGEPAGLGELGEPAGPGE 91
P P AP P PAP A AP AP PA +PA P A PA
Sbjct: 150 PVPVLAPAPAPAPAPVAAPVAAPVAVAVLAPAPAPAPAPAPAPAPVAAPAPAPAPAPAPA 209
Query: 92 PEGPGDPAAAPAEAEEQAVEARQEEEQDL-----DGEKGPSSEGPEEEDGEGFSFKYSPG 146
P P AAP E+ EQ Q ++ L G G + G G + K G
Sbjct: 210 PAPAPAPDAAPQESAEQGANQGQRGQEPLADQLHSGISGRPAAGTAAASANGAAIKKLSG 269
Query: 147 KLRGNQYKK 155
L + + K
Sbjct: 270 PLISDFFAK 278
Score = 43.5 bits (101), Expect = 1e-04
Identities = 42/110 (38%), Positives = 51/110 (46%), Gaps = 10/110 (9%)
Query: 4 PAELLAALPALATA-----LALLLAWLLVRRGAAASPEPARAPPEPAPPAEATG-APAPS 57
P +LA PA A A +A +A ++ A +P PA AP A PA A APAP+
Sbjct: 150 PVPVLAPAPAPAPAPVAAPVAAPVAVAVLAPAPAPAPAPAPAPAPVAAPAPAPAPAPAPA 209
Query: 58 RPCAPEPAASPAGPEEPGEPAGLGELG-EPAGPGEPEG-PGDPAAAPAEA 105
AP P A+P E G A G+ G EP G G PAA A A
Sbjct: 210 PAPAPAPDAAPQESAEQG--ANQGQRGQEPLADQLHSGISGRPAAGTAAA 257
>gi|89276751 alpha 1 type V collagen preproprotein [Homo sapiens]
Length = 1838
Score = 48.9 bits (115), Expect = 3e-06
Identities = 42/133 (31%), Positives = 50/133 (37%), Gaps = 26/133 (19%)
Query: 29 RGAAASPEPARAPPEPAPPAEA--------TGAPAPSRPCAPEPAASPAGPEEPGEPAGL 80
RG P P P PP E G P P P P A GP+ P P G+
Sbjct: 1218 RGFPGPPGPVGLQGLPGPPGEKGETGDVGQMGPPGPPGPRGPSGAPGADGPQGP--PGGI 1275
Query: 81 GELGEPAGPGEPEGPGDPAAAPAEAEEQAVEARQEEEQDLDGEKGPSS-------EGPEE 133
G G GEP G+P P E + + E+ GE GPS +GP
Sbjct: 1276 GNPGAVGEKGEPGEAGEP-GLPGEGGPPGPKGERGEK----GESGPSGAAGPPGPKGPPG 1330
Query: 134 EDGEGFSFKYSPG 146
+DG K SPG
Sbjct: 1331 DDGP----KGSPG 1339
Score = 47.0 bits (110), Expect = 1e-05
Identities = 40/122 (32%), Positives = 48/122 (39%), Gaps = 14/122 (11%)
Query: 30 GAAASPEPARAPPEPAPPAEATGAPAPSRPCAPEPAASPAGPEEPGEPAGLGELGEPAGP 89
G SP P P +P PP E P P+ P G EPG+ G GEP
Sbjct: 1333 GPKGSPGPVGFPGDPGPPGE----PGPAGQDGPPGDKGDDG--EPGQTGSPGPTGEPGPS 1386
Query: 90 GEPEGPGDPAAAPAEAEEQAVEARQEEEQDLDGEKGPSSE-GPEEEDGEGFSFKYSPGKL 148
G P G P PA E + E + E L+G G + GP+ G K P L
Sbjct: 1387 GPPGKRGPP--GPAGPEGRQGEKGAKGEAGLEGPPGKTGPIGPQGAPG-----KPGPDGL 1439
Query: 149 RG 150
RG
Sbjct: 1440 RG 1441
Score = 44.7 bits (104), Expect = 6e-05
Identities = 37/123 (30%), Positives = 43/123 (34%), Gaps = 16/123 (13%)
Query: 30 GAAASPEPARAPPEPAP-----PAEATGAPAPSRPCAPEPAASPAGPEEPGEPAGLGELG 84
G P PA +P E P P G P P P P G + P PAG L
Sbjct: 1078 GPPGPPGPAGSPGERGPAGAAGPIGIPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGLQ 1137
Query: 85 EPAGPGEPEGPGDPAAAPAEAEEQAVEARQEEEQDLDGEKGP----------SSEGPEEE 134
P G P GP P + E E Q+ + GE+GP GP
Sbjct: 1138 GPVGLPGPAGPVGPPGEDGDKGEIG-EPGQKGSKGDKGEQGPPGPTGPQGPIGQPGPSGA 1196
Query: 135 DGE 137
DGE
Sbjct: 1197 DGE 1199
Score = 44.3 bits (103), Expect = 7e-05
Identities = 43/132 (32%), Positives = 49/132 (37%), Gaps = 18/132 (13%)
Query: 22 LAWLLVRRGAAASPEPARAPPEPAPPAEA-----TGAPAPSRPCAPEPAASPAGPE---- 72
L L + G P PA P + PP G P P + P GP
Sbjct: 1028 LPGLAGKEGTKGDPGPAGLPGKDGPPGLRGFPGDRGLPGPVGALGLKGNEGPPGPPGPAG 1087
Query: 73 EPGE--PAGL-GELGEPAGPGE--PEGPGDPAAAPAEAEEQAVEARQ--EEEQDLDGEKG 125
PGE PAG G +G P PG P GP AP E Q R + L G G
Sbjct: 1088 SPGERGPAGAAGPIGIPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGLQGPVGLPGPAG 1147
Query: 126 PSSEGPEEEDGE 137
P GP EDG+
Sbjct: 1148 P--VGPPGEDGD 1157
Score = 41.2 bits (95), Expect = 6e-04
Identities = 37/136 (27%), Positives = 45/136 (33%), Gaps = 42/136 (30%)
Query: 30 GAAASPEPARAPPEPAPPAEA-----------------TGAPAPSRPCAPEPAASPAGPE 72
G P P+ P + PP A G P + P P+ A GP+
Sbjct: 1378 GPTGEPGPSGPPGKRGPPGPAGPEGRQGEKGAKGEAGLEGPPGKTGPIGPQGAPGKPGPD 1437
Query: 73 E-PGEPAGLGELGEPAGPGEPEGPGDPAAAPAEAEEQAVEARQEEEQDLDGEKGPSSE-- 129
G P +GE G P PG P+GP P P L G+ GP E
Sbjct: 1438 GLRGIPGPVGEQGLPGSPG-PDGPPGPMGPPG-------------LPGLKGDSGPKGEKG 1483
Query: 130 --------GPEEEDGE 137
GP E GE
Sbjct: 1484 HPGLIGLIGPPGEQGE 1499
Score = 39.7 bits (91), Expect = 0.002
Identities = 34/130 (26%), Positives = 50/130 (38%), Gaps = 16/130 (12%)
Query: 41 PPEPAPPAEATGAPAPSRPCAPEPAASPAGPEEPGEPAGLGELGEPAGPGEPEGPGDPAA 100
P P P G P P P + ++ P GP+ GE G P PG P PG+
Sbjct: 1523 PSGPIGPPGPPGLPGPPGPKGAKGSSGPTGPK--------GEAGHPGPPGPPGPPGE-VI 1573
Query: 101 APAEAEEQAVEARQEEEQDLDGEKGPS----SEGPEEEDGEGFSFKYSPGKLR---GNQY 153
P + + Q LD G + ++G EE G S K +++ G Q
Sbjct: 1574 QPLPIQASRTRRNIDASQLLDDGNGENYVDYADGMEEIFGSLNSLKLEIEQMKRPLGTQQ 1633
Query: 154 KKMMTKEELE 163
T ++L+
Sbjct: 1634 NPARTCKDLQ 1643
Score = 38.9 bits (89), Expect = 0.003
Identities = 32/103 (31%), Positives = 37/103 (35%), Gaps = 9/103 (8%)
Query: 35 PEPARAPPEPAPPAEATGAPAPSRPCAPEPAASPAGPEEPGEPAGLGELGEPAGPGEPEG 94
P PP P G P P GP P P+G P GP P G
Sbjct: 1217 PRGFPGPPGPVGLQGLPGPPGEKGETGDVGQMGPPGPPGPRGPSGAPGADGPQGP--PGG 1274
Query: 95 PGDPAAAPAEAEEQAVEARQEEEQDLDGEKGPSSEGPEEEDGE 137
G+P A + E + E L GE GP GP+ E GE
Sbjct: 1275 IGNPGAVGEKG-----EPGEAGEPGLPGEGGP--PGPKGERGE 1310
Score = 37.4 bits (85), Expect = 0.009
Identities = 34/119 (28%), Positives = 41/119 (34%), Gaps = 17/119 (14%)
Query: 29 RGAAASPEPARAPPEPAPPAEATGAPAPSRPCAPEPAASPAGPEEPGEPAGLGELGEPAG 88
RG P P EP P G P P P P P G+P G +G
Sbjct: 663 RGDDGEVGPRGLPGEPGP----RGLLGPKGP--PGPPGPPGVTGMDGQPGPKGNVGPQGE 716
Query: 89 PGEPEGPGDPAAAPAEAEEQAVEARQEE----EQDLDGEKG-------PSSEGPEEEDG 136
PG P G+P A + A+ E+ + L G G P EGP E G
Sbjct: 717 PGPPGQQGNPGAQGLPGPQGAIGPPGEKGPLGKPGLPGMPGADGPPGHPGKEGPPGEKG 775
Score = 37.4 bits (85), Expect = 0.009
Identities = 33/116 (28%), Positives = 40/116 (34%), Gaps = 8/116 (6%)
Query: 29 RGAAASPEPA--RAPPEPAP---PAEATGAPAPSRPCAPEPAASPAGPEEPGEPAGLGEL 83
RG P P R P P P TG P P + A P G P P G
Sbjct: 900 RGTPGKPGPRGQRGPTGPRGERGPRGITGKPGPKGNSGGDGPAGPPGERGPNGPQGPTGF 959
Query: 84 GEPAGPGEPEGPGDPAAAPAEAEEQAVEAR--QEEEQDLDGEKGPSSE-GPEEEDG 136
P GP P G P + E + + + G +GP+ E GP E G
Sbjct: 960 PGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPPGVVGPQGPTGETGPMGERG 1015
Score = 36.6 bits (83), Expect = 0.015
Identities = 34/124 (27%), Positives = 43/124 (34%), Gaps = 28/124 (22%)
Query: 28 RRGAAASPEPARAPPEPAPPAEA-----TGAPAPSRPCA-PEPAASPAGPEEPGEPAGLG 81
RRG A S P + P + G P P P+ P P + GE G
Sbjct: 608 RRGRAGSDGARGMPGQTGPKGDRGFDGLAGLPGEKGHRGDPGPSGPPGPPGDDGERGDDG 667
Query: 82 ELGEPAGPGE--------PEGPGDPAAAPAEAEEQAVEARQEEEQDLDGEKGPSSE-GPE 132
E+G PGE P+GP P P +DG+ GP GP+
Sbjct: 668 EVGPRGLPGEPGPRGLLGPKGPPGPPGPPGVT-------------GMDGQPGPKGNVGPQ 714
Query: 133 EEDG 136
E G
Sbjct: 715 GEPG 718
Score = 36.6 bits (83), Expect = 0.015
Identities = 25/76 (32%), Positives = 28/76 (36%), Gaps = 3/76 (3%)
Query: 29 RGAAASPEPARAPPEPAPPAEATGAPAPSRPCAPEPAASPAGPEEPGEPAGLGELGEPAG 88
+G P P P E TG + P P P GP GE +GE G P
Sbjct: 963 KGPPGPPGKDGLPGHPGQRGE-TGFQGKTGPPGPPGVVGPQGPT--GETGPMGERGHPGP 1019
Query: 89 PGEPEGPGDPAAAPAE 104
PG P G P A E
Sbjct: 1020 PGPPGEQGLPGLAGKE 1035
Score = 35.0 bits (79), Expect = 0.044
Identities = 24/65 (36%), Positives = 25/65 (38%), Gaps = 9/65 (13%)
Query: 43 EPAPPAE-----ATGAPAPSRPCAPEPAASPAG-PEEPGEPAGLGELGEPAG---PGEPE 93
EP PP + A G P P P P G P PG P G G P PGE
Sbjct: 716 EPGPPGQQGNPGAQGLPGPQGAIGPPGEKGPLGKPGLPGMPGADGPPGHPGKEGPPGEKG 775
Query: 94 GPGDP 98
G G P
Sbjct: 776 GQGPP 780
Score = 34.3 bits (77), Expect = 0.075
Identities = 28/89 (31%), Positives = 34/89 (38%), Gaps = 20/89 (22%)
Query: 36 EPARAPPE--PAPPA------EATGAPAPSRPCAPEPAA--------SPAGPEEP----G 75
+P +P E P PA E G P + EPA P GPE P G
Sbjct: 422 DPTSSPSEIGPGMPANQDTIYEGIGGPRGEKGQKGEPAIIEPGMLIEGPPGPEGPAGLPG 481
Query: 76 EPAGLGELGEPAGPGEPEGPGDPAAAPAE 104
P +G G+ PGE PG P A+
Sbjct: 482 PPGTMGPTGQVGDPGERGPPGRPGLPGAD 510
Score = 34.3 bits (77), Expect = 0.075
Identities = 32/110 (29%), Positives = 41/110 (37%), Gaps = 20/110 (18%)
Query: 29 RGAAASPEP--ARAPPEPAPPAEATGAPAPSRPCAPEPAASPAGPEEPGEPAGLGELGEP 86
+GA P P R P P G+P P P P P P P G+ GE G P
Sbjct: 1428 QGAPGKPGPDGLRGIPGPVGEQGLPGSPGPDGP--PGPMGPPGLPGLKGDSGPKGEKGHP 1485
Query: 87 AGPGEPEGPGDPAAAPAEAEEQAVEARQEEEQDLDGEKGPSSEGPEEEDG 136
G PG E ++ ++ L G +G S GP+ E G
Sbjct: 1486 GLIGLIGPPG--------------EQGEKGDRGLPGPQG--SSGPKGEQG 1519
Score = 33.9 bits (76), Expect = 0.098
Identities = 25/86 (29%), Positives = 33/86 (38%), Gaps = 16/86 (18%)
Query: 44 PAPPAEATGAPAPSRPCAPEPAASPAGPEEPGEPAGLGELGEPAGPGEPEGPGDPAAAPA 103
PA P TG P P P P GEP +G P GP +GP PA P
Sbjct: 560 PAGPMGLTGRPGPVGP--------PGSGGLKGEPGDVG----PQGPRGVQGPPGPAGKPG 607
Query: 104 EAEEQAVEARQEEEQDLDGEKGPSSE 129
+ A + + + G+ GP +
Sbjct: 608 ----RRGRAGSDGARGMPGQTGPKGD 629
Score = 32.7 bits (73), Expect = 0.22
Identities = 39/138 (28%), Positives = 46/138 (33%), Gaps = 24/138 (17%)
Query: 28 RRGAAASPEPARAPPEPAPPAEATGAPAPSRPCAPEPAASPAGPEEPGEPAGLGELGEPA 87
++G A EP P P G P P P P P E G P G G
Sbjct: 454 QKGEPAIIEPGMLIEGPPGPEGPAGLPGP--PGTMGPTGQVGDPGERGPPGRPGLPGADG 511
Query: 88 GPGEP----------EGPGD-----PAAAPAEAEEQAVEARQEEEQDLDGEKGP----SS 128
PG P G GD P + E++ QA+ Q+ L G GP
Sbjct: 512 LPGPPGTMLMLPFRFGGGGDAGSKGPMVSAQESQAQAI--LQQARLALRGPAGPMGLTGR 569
Query: 129 EGPEEEDGEGFSFKYSPG 146
GP G G K PG
Sbjct: 570 PGPVGPPGSG-GLKGEPG 586
Score = 32.7 bits (73), Expect = 0.22
Identities = 34/119 (28%), Positives = 42/119 (35%), Gaps = 16/119 (13%)
Query: 30 GAAASPEPARAPPEPAPPAEATGAPAPSRPCAPEPAASPAGPEEPGEPAGLGELGEPAGP 89
GA P P A PP E P P P P P + G P G G P GP
Sbjct: 727 GAQGLPGPQGAI---GPPGEKGPLGKPGLPGMPGADGPPGHPGKEGPPGEKGGQG-PPGP 782
Query: 90 GEPEG-PGDPAAAPAEAEEQAVEARQEEEQD----------LDGEKGP-SSEGPEEEDG 136
P G PG A+ + E+ +D + G++G GP EDG
Sbjct: 783 QGPIGYPGPRGVKGADGIRGLKGTKGEKGEDGFPGFKGDMGIKGDRGEIGPPGPRGEDG 841
Score = 32.3 bits (72), Expect = 0.29
Identities = 35/124 (28%), Positives = 41/124 (33%), Gaps = 10/124 (8%)
Query: 17 ALALLLAWLLVRRGAAASPEPARAPPEPAPPAEA--TGAPAPSRPCAPEPAASPAGPEEP 74
A A+L L RG A P PP G P P P P GP
Sbjct: 546 AQAILQQARLALRGPAGPMGLTGRPGPVGPPGSGGLKGEPGDVGPQGPRGVQGPPGPA-- 603
Query: 75 GEPAGLGELGEPAGPGEPEGPGDPAAAPAEAEEQAVEARQEEEQDLDGEKGPSS-EGPEE 133
G+P G G G P G + A E+ G+ GPS GP
Sbjct: 604 GKPGRRGRAGSDGARGMPGQTGPKGDRGFDG-----LAGLPGEKGHRGDPGPSGPPGPPG 658
Query: 134 EDGE 137
+DGE
Sbjct: 659 DDGE 662
Score = 30.4 bits (67), Expect = 1.1
Identities = 20/65 (30%), Positives = 22/65 (33%), Gaps = 5/65 (7%)
Query: 46 PPAEA-----TGAPAPSRPCAPEPAASPAGPEEPGEPAGLGELGEPAGPGEPEGPGDPAA 100
PP E G P P P+ GP P P G L P GP +G P
Sbjct: 1493 PPGEQGEKGDRGLPGPQGSSGPKGEQGITGPSGPIGPPGPPGLPGPPGPKGAKGSSGPTG 1552
Query: 101 APAEA 105
EA
Sbjct: 1553 PKGEA 1557
Score = 30.0 bits (66), Expect = 1.4
Identities = 20/57 (35%), Positives = 23/57 (40%), Gaps = 6/57 (10%)
Query: 30 GAAASPEPARAPPEPAPPAEATGAPAPSRPCAPEPAASPAGPEEPGEPAGLGELGEP 86
G P P P P P GA S P P+ A GP PG P GE+ +P
Sbjct: 1525 GPIGPPGPPGLPGPPGPK----GAKGSSGPTGPKGEAGHPGP--PGPPGPPGEVIQP 1575
Score = 29.3 bits (64), Expect = 2.4
Identities = 18/47 (38%), Positives = 19/47 (40%), Gaps = 2/47 (4%)
Query: 52 GAPAPSRPCAPEPAASPAGPEEPGEPAGLGELGEPAGPGEPEGPGDP 98
G P P PE GP G+P LG GE G P PG P
Sbjct: 832 GPPGPRGEDGPEGPKGRGGPN--GDPGPLGPPGEKGKLGVPGLPGYP 876
>gi|157168329 formin 1 [Homo sapiens]
Length = 1196
Score = 48.5 bits (114), Expect = 4e-06
Identities = 40/142 (28%), Positives = 54/142 (38%), Gaps = 16/142 (11%)
Query: 35 PEPARAPPEPAPPAEATGAPAPSRPCAPEPAASPAG---PEEPGEPAGLGELGEPAGPGE 91
P + PP P PP +PAP P P PA P G P PG GLG
Sbjct: 692 PPSSAGPPPPPPPPPLPNSPAPPNPGGPPPAPPPPGLAPPPPPGLFFGLGS-------SS 744
Query: 92 PEGPGDPAAAPAEAEEQAVEAR---QEEEQDLDGEKGPSSEGPEEEDGEGFSFKYSPGKL 148
+ P PA P+ + R + Q+ S E P+ D F + +S
Sbjct: 745 SQCPRKPAIEPSCPMKPLYWTRIQISDRSQNATPTLWDSLEEPDIRDPSEFEYLFSKDT- 803
Query: 149 RGNQYKKMMTKEELEEEQRVQK 170
Q KK E E++ +V+K
Sbjct: 804 --TQQKKKPLSETYEKKNKVKK 823
Score = 41.2 bits (95), Expect = 6e-04
Identities = 31/87 (35%), Positives = 32/87 (36%), Gaps = 16/87 (18%)
Query: 32 AASPEPARAPP-----------EPAPPAE--ATGAPAPSRPCAPEPAASP--AGPEEPGE 76
A P PA PP PAPP + G P P P P P P AGP P
Sbjct: 644 ALPPPPASIPPPPPLPSGLGSLSPAPPMPPVSAGPPLPPPPPPPPPLPPPSSAGPPPPPP 703
Query: 77 PAGLGELGEPAGP-GEPEGPGDPAAAP 102
P L P P G P P P AP
Sbjct: 704 PPPLPNSPAPPNPGGPPPAPPPPGLAP 730
>gi|237757312 synaptojanin 1 isoform c [Homo sapiens]
Length = 1295
Score = 48.1 bits (113), Expect = 5e-06
Identities = 29/97 (29%), Positives = 40/97 (41%), Gaps = 4/97 (4%)
Query: 37 PARAPPEPAPPAEATGAPAPSRPCAPEPAASPAGPEEPGEPAGLGELGEPAGPGEPEGPG 96
P+RAP P A +P ++P P P PA P EP P + P P P+ P
Sbjct: 1068 PSRAPSRTPGPPSAQSSPIDAQPATPLPQKDPAQPLEPKRPPPPRPVAPPTRPAPPQRPP 1127
Query: 97 DPAA----APAEAEEQAVEARQEEEQDLDGEKGPSSE 129
P+ AP E A ++ +D G PS +
Sbjct: 1128 PPSGARSPAPTRKEFGAPKSPGTTRKDNIGRSQPSPQ 1164
Score = 42.0 bits (97), Expect = 4e-04
Identities = 36/127 (28%), Positives = 45/127 (35%), Gaps = 12/127 (9%)
Query: 33 ASPEPARAPPEPAPPAEATGAPAPSRPCAPEPAASPA-------GPEEPG----EPAGLG 81
A P + PP P P A T P RP P A SPA P+ PG + G
Sbjct: 1100 AQPLEPKRPPPPRPVAPPTRPAPPQRPPPPSGARSPAPTRKEFGAPKSPGTTRKDNIGRS 1159
Query: 82 ELGEPAGPGEPEGPGDPAAAPA-EAEEQAVEARQEEEQDLDGEKGPSSEGPEEEDGEGFS 140
+ AG P G A P + A Q + G P S+ E +G +
Sbjct: 1160 QPSPQAGLAGPGPAGYSTARPTIPPRAGVISAPQSHARASAGRLTPESQSKTSETSKGST 1219
Query: 141 FKYSPGK 147
F P K
Sbjct: 1220 FLPEPLK 1226
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.305 0.128 0.366
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 11,631,940
Number of Sequences: 37866
Number of extensions: 939402
Number of successful extensions: 31225
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 1368
Number of HSP's successfully gapped in prelim test: 1875
Number of HSP's that attempted gapping in prelim test: 8263
Number of HSP's gapped (non-prelim): 13117
length of query: 204
length of database: 18,247,518
effective HSP length: 97
effective length of query: 107
effective length of database: 14,574,516
effective search space: 1559473212
effective search space used: 1559473212
T: 11
A: 40
X1: 16 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 43 (21.9 bits)
S2: 59 (27.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.