Guide to the Human Genome
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Search of human proteins with 134133279

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|134133279 SP140 nuclear body protein-like [Homo sapiens]
         (580 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|134133279 SP140 nuclear body protein-like [Homo sapiens]          1200   0.0  
gi|217330601 SP140 nuclear body protein isoform 1 [Homo sapiens]      793   0.0  
gi|122939208 nuclear antigen Sp100 isoform 1 [Homo sapiens]           407   e-113
gi|190343006 SP110 nuclear body protein isoform c [Homo sapiens]      306   3e-83
gi|19923236 nuclear antigen Sp100 isoform 2 [Homo sapiens]            285   8e-77
gi|190343010 SP110 nuclear body protein isoform a [Homo sapiens]      264   1e-70
gi|190343008 SP110 nuclear body protein isoform b [Homo sapiens]      119   8e-27
gi|52487277 SP140 nuclear body protein isoform 2 [Homo sapiens]       117   2e-26
gi|74027251 tripartite motif-containing 33 protein isoform beta ...   106   5e-23
gi|74027249 tripartite motif-containing 33 protein isoform alpha...   103   4e-22
gi|47419911 transcriptional intermediary factor 1 alpha isoform ...   102   7e-22
gi|47419909 transcriptional intermediary factor 1 alpha isoform ...   102   7e-22
gi|209977097 tripartite motif-containing 66 [Homo sapiens]             90   5e-18
gi|4557291 autoimmune regulator isoform 1 [Homo sapiens]               79   9e-15
gi|4557293 autoimmune regulator isoform 2 [Homo sapiens]               64   5e-10
gi|38016945 deformed epidermal autoregulatory factor 1 [Homo sap...    63   6e-10
gi|5032179 tripartite motif-containing 28 protein [Homo sapiens]       63   8e-10
gi|38788260 bromodomain PHD finger transcription factor isoform ...    57   5e-08
gi|38788274 bromodomain PHD finger transcription factor isoform ...    57   5e-08
gi|75677357 PHD finger protein 12 isoform 1 [Homo sapiens]             55   2e-07
gi|30842829 PHD finger protein 12 isoform 2 [Homo sapiens]             55   2e-07
gi|156546910 BRAF35/HDAC2 complex isoform b [Homo sapiens]             53   9e-07
gi|156546894 BRAF35/HDAC2 complex isoform a [Homo sapiens]             53   9e-07
gi|51599156 chromodomain helicase DNA binding protein 4 [Homo sa...    51   3e-06
gi|24308089 chromodomain helicase DNA binding protein 5 [Homo sa...    51   3e-06
gi|52630326 chromodomain helicase DNA binding protein 3 isoform ...    49   1e-05
gi|52630322 chromodomain helicase DNA binding protein 3 isoform ...    49   1e-05
gi|158420731 chromodomain helicase DNA binding protein 3 isoform...    49   1e-05
gi|34335264 zinc finger, MYND-type containing 8 isoform c [Homo ...    47   4e-05
gi|27477095 nuclear receptor binding SET domain protein 1 isofor...    45   1e-04

>gi|134133279 SP140 nuclear body protein-like [Homo sapiens]
          Length = 580

 Score = 1200 bits (3104), Expect = 0.0
 Identities = 580/580 (100%), Positives = 580/580 (100%)

Query: 1   MAGGGSDLSTRGLNGGVSQVANEMNHLPAHSQSLQRLFTEDQDVDEGLVYDTVFKHFKRH 60
           MAGGGSDLSTRGLNGGVSQVANEMNHLPAHSQSLQRLFTEDQDVDEGLVYDTVFKHFKRH
Sbjct: 1   MAGGGSDLSTRGLNGGVSQVANEMNHLPAHSQSLQRLFTEDQDVDEGLVYDTVFKHFKRH 60

Query: 61  KLEISNAIKKTFPFLEGLRDRELITNKMFEDSEDSCRNLVPVQRVVYNVLSELEKTFNLS 120
           KLEISNAIKKTFPFLEGLRDRELITNKMFEDSEDSCRNLVPVQRVVYNVLSELEKTFNLS
Sbjct: 61  KLEISNAIKKTFPFLEGLRDRELITNKMFEDSEDSCRNLVPVQRVVYNVLSELEKTFNLS 120

Query: 121 VLEALFSEVNMQEYPDLIHIYKSFKNAIQDKLSFQESDRKEREERPDIKLSLKQGEVPES 180
           VLEALFSEVNMQEYPDLIHIYKSFKNAIQDKLSFQESDRKEREERPDIKLSLKQGEVPES
Sbjct: 121 VLEALFSEVNMQEYPDLIHIYKSFKNAIQDKLSFQESDRKEREERPDIKLSLKQGEVPES 180

Query: 181 PEARKESDQACGKMDTVDIANNSTLGKPKRKRRKKKGHGWSRMGTRTQKNNQQNDNSKAD 240
           PEARKESDQACGKMDTVDIANNSTLGKPKRKRRKKKGHGWSRMGTRTQKNNQQNDNSKAD
Sbjct: 181 PEARKESDQACGKMDTVDIANNSTLGKPKRKRRKKKGHGWSRMGTRTQKNNQQNDNSKAD 240

Query: 241 GQLVSSEKKANMNLKDLSKIRGRKRGKPGTHFTQSDRAPQKRVRSRASRKHKDETVDFQA 300
           GQLVSSEKKANMNLKDLSKIRGRKRGKPGTHFTQSDRAPQKRVRSRASRKHKDETVDFQA
Sbjct: 241 GQLVSSEKKANMNLKDLSKIRGRKRGKPGTHFTQSDRAPQKRVRSRASRKHKDETVDFQA 300

Query: 301 PLLPVTCGGVKGILHKEKLEQGTLAKCIQTEDGKWFTPMEFEIKGGYARSKNWRLSVRCG 360
           PLLPVTCGGVKGILHKEKLEQGTLAKCIQTEDGKWFTPMEFEIKGGYARSKNWRLSVRCG
Sbjct: 301 PLLPVTCGGVKGILHKEKLEQGTLAKCIQTEDGKWFTPMEFEIKGGYARSKNWRLSVRCG 360

Query: 361 GWPLRRLMEEGSLPNPPRIYYRNKKRILKSQNNSSVDPCMRNLDECEVCRDGGELFCCDT 420
           GWPLRRLMEEGSLPNPPRIYYRNKKRILKSQNNSSVDPCMRNLDECEVCRDGGELFCCDT
Sbjct: 361 GWPLRRLMEEGSLPNPPRIYYRNKKRILKSQNNSSVDPCMRNLDECEVCRDGGELFCCDT 420

Query: 421 CSRVFHEDCHIPPVESEKTPWNCIFCRMKESPGSQQCCQESEVLERQMCPEEQLKCEFLL 480
           CSRVFHEDCHIPPVESEKTPWNCIFCRMKESPGSQQCCQESEVLERQMCPEEQLKCEFLL
Sbjct: 421 CSRVFHEDCHIPPVESEKTPWNCIFCRMKESPGSQQCCQESEVLERQMCPEEQLKCEFLL 480

Query: 481 LKVYCCSESSFFAKIPYYYYIREACQGLKEPMWLDKIKKRLNEHGYPQVEGFVQDMRLIF 540
           LKVYCCSESSFFAKIPYYYYIREACQGLKEPMWLDKIKKRLNEHGYPQVEGFVQDMRLIF
Sbjct: 481 LKVYCCSESSFFAKIPYYYYIREACQGLKEPMWLDKIKKRLNEHGYPQVEGFVQDMRLIF 540

Query: 541 QNHRASYKYKDFGQMGLRLEAEFEKDFKEVFAIQETNGNS 580
           QNHRASYKYKDFGQMGLRLEAEFEKDFKEVFAIQETNGNS
Sbjct: 541 QNHRASYKYKDFGQMGLRLEAEFEKDFKEVFAIQETNGNS 580


>gi|217330601 SP140 nuclear body protein isoform 1 [Homo sapiens]
          Length = 867

 Score =  793 bits (2048), Expect = 0.0
 Identities = 374/405 (92%), Positives = 388/405 (95%)

Query: 176 EVPESPEARKESDQACGKMDTVDIANNSTLGKPKRKRRKKKGHGWSRMGTRTQKNNQQND 235
           EVP SPEAR ESDQACG MDTVDIANNSTLGKPKRKRRKK+GHGWSRM  R Q+N+QQND
Sbjct: 463 EVPGSPEARTESDQACGTMDTVDIANNSTLGKPKRKRRKKRGHGWSRMRMRRQENSQQND 522

Query: 236 NSKADGQLVSSEKKANMNLKDLSKIRGRKRGKPGTHFTQSDRAPQKRVRSRASRKHKDET 295
           NSKADGQ+VSSEKKAN+NLKDLSKIRGRKRGKPGT FTQSDRA QKRVRSRASRKHKDET
Sbjct: 523 NSKADGQVVSSEKKANVNLKDLSKIRGRKRGKPGTRFTQSDRAAQKRVRSRASRKHKDET 582

Query: 296 VDFQAPLLPVTCGGVKGILHKEKLEQGTLAKCIQTEDGKWFTPMEFEIKGGYARSKNWRL 355
           VDF+APLLPVTCGGVKGILHK+KL+QG L KCIQTEDGKWFTP EFEIKGG+ARSKNWRL
Sbjct: 583 VDFKAPLLPVTCGGVKGILHKKKLQQGILVKCIQTEDGKWFTPTEFEIKGGHARSKNWRL 642

Query: 356 SVRCGGWPLRRLMEEGSLPNPPRIYYRNKKRILKSQNNSSVDPCMRNLDECEVCRDGGEL 415
           SVRCGGWPLR LME G LP+PPRI YR KKRILKSQNNSSVDPCMRNLDECEVCRDGGEL
Sbjct: 643 SVRCGGWPLRWLMENGFLPDPPRIRYRKKKRILKSQNNSSVDPCMRNLDECEVCRDGGEL 702

Query: 416 FCCDTCSRVFHEDCHIPPVESEKTPWNCIFCRMKESPGSQQCCQESEVLERQMCPEEQLK 475
           FCCDTCSRVFHEDCHIPPVE+E+TPWNCIFCRMKESPGSQQCCQESEVLERQMCPEEQLK
Sbjct: 703 FCCDTCSRVFHEDCHIPPVEAERTPWNCIFCRMKESPGSQQCCQESEVLERQMCPEEQLK 762

Query: 476 CEFLLLKVYCCSESSFFAKIPYYYYIREACQGLKEPMWLDKIKKRLNEHGYPQVEGFVQD 535
           CEFLLLKVYCCSESSFFAKIPYYYYIREACQGLKEPMWLDKIKKRLNEHGYPQVEGFVQD
Sbjct: 763 CEFLLLKVYCCSESSFFAKIPYYYYIREACQGLKEPMWLDKIKKRLNEHGYPQVEGFVQD 822

Query: 536 MRLIFQNHRASYKYKDFGQMGLRLEAEFEKDFKEVFAIQETNGNS 580
           MRLIFQNHRASYKYKDFGQMG RLEAEFEK+FKEVFAIQETNGN+
Sbjct: 823 MRLIFQNHRASYKYKDFGQMGFRLEAEFEKNFKEVFAIQETNGNN 867



 Score =  132 bits (333), Expect = 7e-31
 Identities = 68/170 (40%), Positives = 105/170 (61%), Gaps = 11/170 (6%)

Query: 40  EDQDVDEGLVYDTVFKHFKRHKLEISNAIKKTFPFLEGLRDRELITNKMFEDSEDSCRNL 99
           E Q++ E +  + +F+ F+ +K+EI++AI + FPFL GLRDR  I+ +M+E  +++ RNL
Sbjct: 29  EGQNLQEQVCPEPIFRFFRENKVEIASAITRPFPFLMGLRDRSFISEQMYEHFQEAFRNL 88

Query: 100 VPVQRVVYNVLSELEKTFNLSVLEALFSEVNMQEYPDLIHIYKSFKNAIQDKLSFQESDR 159
           VPV RV+Y VLSELEKTF  S LEALFS +N+  YPDL  IY+SF+N   +    Q ++ 
Sbjct: 89  VPVTRVMYCVLSELEKTFGWSHLEALFSRINLMAYPDLNEIYRSFQNVCYEHSPLQMNNV 148

Query: 160 KEREERPDIKLSLKQGEVPESPEARKESDQACGKMDTVDIANNSTLGKPK 209
            + E+RP +            P  ++E+  AC +MD + +   +    P+
Sbjct: 149 NDLEDRPRL-----------LPYGKQENSNACHEMDDIAVPQEALSSSPR 187


>gi|122939208 nuclear antigen Sp100 isoform 1 [Homo sapiens]
          Length = 885

 Score =  407 bits (1046), Expect = e-113
 Identities = 218/407 (53%), Positives = 267/407 (65%), Gaps = 28/407 (6%)

Query: 177 VPESPEARKESDQACGKMDTVDIANNSTLGKPKRKRRKKKGHGWSRMGTRTQKNNQQNDN 236
           VP S EAR ES QA   MDT+D+ NNSTL K   KRRKK+ H       R++ N  Q   
Sbjct: 498 VPRSQEARTESSQASDMMDTMDVENNSTLEKHSGKRRKKRRH-------RSKVNGLQRGR 550

Query: 237 SKADGQLVSSEKKANMNLKDLSKIRGRKRGKPGTHFTQSDRAPQKRVRSRASRKHKDETV 296
            K         K   +N K + K R ++RG+      +++  P KR R R  R  KDE +
Sbjct: 551 KKD-----RPRKHLTLNNK-VQKKRWQQRGR------KANTRPLKRRRKRGPRIPKDENI 598

Query: 297 DFQAPLLPVTCGGVKGILHKEKLEQGTLAKCIQTEDGKWFTPMEFEIKGGYARSKNWRLS 356
           +F+   LPVTCG VKG L+KE+ +QGT  KCIQ+ED KWFTP EFEI+G    SKNW+LS
Sbjct: 599 NFKQSELPVTCGEVKGTLYKERFKQGTSKKCIQSEDKKWFTPREFEIEGDRGASKNWKLS 658

Query: 357 VRCGGWPLRRLMEEGSLPNPPRIYYRNKKRILKSQNNSSVDPCMRNLDECEVCRDGGELF 416
           +RCGG+ L+ LME   LP PP      KKRIL+S NN+ VDPC  N + CEVC   G LF
Sbjct: 659 IRCGGYTLKVLMENKFLPEPPS---TRKKRILESHNNTLVDPCPENSNICEVCNKWGRLF 715

Query: 417 CCDTCSRVFHEDCHIPPVESEKTPWNCIFCRMK----ESPGSQQCCQESEVLERQMCPEE 472
           CCDTC R FHE CHIP VE+ K PW+CIFCR+K      P SQ   QESEVL RQM PEE
Sbjct: 716 CCDTCPRSFHEHCHIPSVEANKNPWSCIFCRIKTIQERCPESQSGHQESEVLMRQMLPEE 775

Query: 473 QLKCEFLLLKVYCCSESSFFAKIPYYYYIREACQGLKEPMWLDKIKKRLNEHGYPQVEGF 532
           QLKCEFLLLKVYC S+S FFA  PYY   RE  QG ++PMWL+K+K  LNE  Y +VEGF
Sbjct: 776 QLKCEFLLLKVYCDSKSCFFASEPYYN--REGSQGPQKPMWLNKVKTSLNEQMYTRVEGF 833

Query: 533 VQDMRLIFQNHRASYKYKDFGQMGLRLEAEFEKDFKEVFAIQETNGN 579
           VQDMRLIF NH+  Y+   F ++G++++  FEK+F+ +FAIQET+ N
Sbjct: 834 VQDMRLIFHNHKEFYREDKFTRLGIQVQDIFEKNFRNIFAIQETSKN 880



 Score =  285 bits (729), Expect = 8e-77
 Identities = 141/175 (80%), Positives = 156/175 (89%)

Query: 1   MAGGGSDLSTRGLNGGVSQVANEMNHLPAHSQSLQRLFTEDQDVDEGLVYDTVFKHFKRH 60
           MAGGG DLSTR LN  +S VANEMNHLPAHS  LQR+FTEDQ VD+ L+YD VFKHFKR+
Sbjct: 1   MAGGGGDLSTRRLNECISPVANEMNHLPAHSHDLQRMFTEDQGVDDRLLYDIVFKHFKRN 60

Query: 61  KLEISNAIKKTFPFLEGLRDRELITNKMFEDSEDSCRNLVPVQRVVYNVLSELEKTFNLS 120
           K+EISNAIKKTFPFLEGLRDR+LITNKMFEDS+DSCRNLVPVQRVVYNVLSELEKTFNL 
Sbjct: 61  KVEISNAIKKTFPFLEGLRDRDLITNKMFEDSQDSCRNLVPVQRVVYNVLSELEKTFNLP 120

Query: 121 VLEALFSEVNMQEYPDLIHIYKSFKNAIQDKLSFQESDRKEREERPDIKLSLKQG 175
           VLEALFS+VNMQEYPDLIHIYK F+N I DKL  QES+ +EREER  ++LSL+QG
Sbjct: 121 VLEALFSDVNMQEYPDLIHIYKGFENVIHDKLPLQESEEEEREERSGLQLSLEQG 175


>gi|190343006 SP110 nuclear body protein isoform c [Homo sapiens]
          Length = 713

 Score =  306 bits (785), Expect = 3e-83
 Identities = 173/406 (42%), Positives = 228/406 (56%), Gaps = 47/406 (11%)

Query: 182 EARKESDQACGKMDTVDIANNSTLGK-----PKRKRRKKKG-----HGWSRMGTRTQKNN 231
           +AR E  +     + +D  +    GK     P   RR  +G     HG         K  
Sbjct: 337 KARTECARKSRSEEIIDGTSEMNEGKRSQKTPSTPRRVTQGAASPGHGIQEKLQVVDKVT 396

Query: 232 QQNDNSKADGQLVSSEKKANMNLKDLSKIRGRKRGKPGTHFTQSDRAPQKRVRSRASRKH 291
           Q+ D+S  + +++   +KA    K   K R +++ K     + S R  QK +  R   K 
Sbjct: 397 QRKDDSTWNSEVMMRVQKART--KCARKSRSKEKKKEKDICSSSKRRFQKNIHRRG--KP 452

Query: 292 KDETVDFQAPLLPVTCGGVKGILHKEKLEQGTLAKCIQTEDGKWFTPMEFEIKGGYARSK 351
           K +TVDF    LPVTCG  KGIL+K+K++ G+  KCI+ EDG W TP EFE++G    +K
Sbjct: 453 KSDTVDFHCSKLPVTCGEAKGILYKKKMKHGSSVKCIRNEDGTWLTPNEFEVEGKGRNAK 512

Query: 352 NWRLSVRCGGWPLRRLMEEGSLPNPPRIYYRNKKRILKSQNNSSVDPCMRNLDECEVCRD 411
           NW+ ++RC G  L  L++                               +N DECEVC  
Sbjct: 513 NWKRNIRCEGMTLGELLKR------------------------------KNSDECEVCCQ 542

Query: 412 GGELFCCDTCSRVFHEDCHIPPVESEKTPWNCIFCRMKESPGSQQCCQESEVLERQMCPE 471
           GG+L CC TC RVFHEDCHIPPVE+++  W+C FCRMK S GSQQC   S+ LERQM P+
Sbjct: 543 GGQLLCCGTCPRVFHEDCHIPPVEAKRMLWSCTFCRMKRSSGSQQCHHVSKTLERQMQPQ 602

Query: 472 EQLKCEFLLLKVYCCSESSFFAKIPYYYYIREACQGLKEPMWLDKIKKRLNEHGYPQVEG 531
           +QLKCEFLLLK YC  +SSFF  IP  + IR+  +  +E MWLD +K+RL    Y  V  
Sbjct: 603 DQLKCEFLLLKAYCHPQSSFFTGIP--FNIRDYGEPFQEAMWLDLVKERLITEMY-TVAW 659

Query: 532 FVQDMRLIFQNHRASYKYKDFGQMGLRLEAEFEKDFKEVFAIQETN 577
           FV+DMRL+F+NH+  YK  DFGQ+GL LEAEFEKD K+V    E N
Sbjct: 660 FVRDMRLMFRNHKTFYKASDFGQVGLDLEAEFEKDLKDVLGFHEAN 705



 Score =  119 bits (298), Expect = 8e-27
 Identities = 56/109 (51%), Positives = 82/109 (75%), Gaps = 5/109 (4%)

Query: 37  LFTEDQDVDEGLVYDTVFKHFKRHKLEISNAIKKTFPFLEGLRDRELITNKMFEDSEDSC 96
           +FT  + ++E L     F+HF   KL I+ AI K FPF EGL D  +IT +M+ +S ++C
Sbjct: 1   MFTMTRAMEEAL-----FQHFMHQKLGIAYAIHKPFPFFEGLLDNSIITKRMYMESLEAC 55

Query: 97  RNLVPVQRVVYNVLSELEKTFNLSVLEALFSEVNMQEYPDLIHIYKSFK 145
           RNL+PV RVV+N+L++LE+TFNLS+L  LFS++N++EYP+L+ IY+SFK
Sbjct: 56  RNLIPVSRVVHNILTQLERTFNLSLLVTLFSQINLREYPNLVTIYRSFK 104


>gi|19923236 nuclear antigen Sp100 isoform 2 [Homo sapiens]
          Length = 879

 Score =  285 bits (729), Expect = 8e-77
 Identities = 141/175 (80%), Positives = 156/175 (89%)

Query: 1   MAGGGSDLSTRGLNGGVSQVANEMNHLPAHSQSLQRLFTEDQDVDEGLVYDTVFKHFKRH 60
           MAGGG DLSTR LN  +S VANEMNHLPAHS  LQR+FTEDQ VD+ L+YD VFKHFKR+
Sbjct: 1   MAGGGGDLSTRRLNECISPVANEMNHLPAHSHDLQRMFTEDQGVDDRLLYDIVFKHFKRN 60

Query: 61  KLEISNAIKKTFPFLEGLRDRELITNKMFEDSEDSCRNLVPVQRVVYNVLSELEKTFNLS 120
           K+EISNAIKKTFPFLEGLRDR+LITNKMFEDS+DSCRNLVPVQRVVYNVLSELEKTFNL 
Sbjct: 61  KVEISNAIKKTFPFLEGLRDRDLITNKMFEDSQDSCRNLVPVQRVVYNVLSELEKTFNLP 120

Query: 121 VLEALFSEVNMQEYPDLIHIYKSFKNAIQDKLSFQESDRKEREERPDIKLSLKQG 175
           VLEALFS+VNMQEYPDLIHIYK F+N I DKL  QES+ +EREER  ++LSL+QG
Sbjct: 121 VLEALFSDVNMQEYPDLIHIYKGFENVIHDKLPLQESEEEEREERSGLQLSLEQG 175



 Score =  187 bits (474), Expect = 3e-47
 Identities = 108/223 (48%), Positives = 135/223 (60%), Gaps = 22/223 (9%)

Query: 177 VPESPEARKESDQACGKMDTVDIANNSTLGKPKRKRRKKKGHGWSRMGTRTQKNNQQNDN 236
           VP S EAR ES QA   MDT+D+ NNSTL K   KRRKK+ H       R++ N  Q   
Sbjct: 498 VPRSQEARTESSQASDMMDTMDVENNSTLEKHSGKRRKKRRH-------RSKVNGLQRGR 550

Query: 237 SKADGQLVSSEKKANMNLKDLSKIRGRKRGKPGTHFTQSDRAPQKRVRSRASRKHKDETV 296
            K         K   +N K + K R ++RG+      +++  P KR R R  R  KDE +
Sbjct: 551 KKD-----RPRKHLTLNNK-VQKKRWQQRGR------KANTRPLKRRRKRGPRIPKDENI 598

Query: 297 DFQAPLLPVTCGGVKGILHKEKLEQGTLAKCIQTEDGKWFTPMEFEIKGGYARSKNWRLS 356
           +F+   LPVTCG VKG L+KE+ +QGT  KCIQ+ED KWFTP EFEI+G    SKNW+LS
Sbjct: 599 NFKQSELPVTCGEVKGTLYKERFKQGTSKKCIQSEDKKWFTPREFEIEGDRGASKNWKLS 658

Query: 357 VRCGGWPLRRLMEEGSLPNPPRIYYRNKKRILKSQNNSSVDPC 399
           +RCGG+ L+ LME   LP PP      KKRIL+S NN+ VDPC
Sbjct: 659 IRCGGYTLKVLMENKFLPEPPS---TRKKRILESHNNTLVDPC 698


>gi|190343010 SP110 nuclear body protein isoform a [Homo sapiens]
          Length = 689

 Score =  264 bits (675), Expect = 1e-70
 Identities = 157/406 (38%), Positives = 210/406 (51%), Gaps = 71/406 (17%)

Query: 182 EARKESDQACGKMDTVDIANNSTLGK-----PKRKRRKKKG-----HGWSRMGTRTQKNN 231
           +AR E  +     + +D  +    GK     P   RR  +G     HG         K  
Sbjct: 337 KARTECARKSRSEEIIDGTSEMNEGKRSQKTPSTPRRVTQGAASPGHGIQEKLQVVDKVT 396

Query: 232 QQNDNSKADGQLVSSEKKANMNLKDLSKIRGRKRGKPGTHFTQSDRAPQKRVRSRASRKH 291
           Q+ D+S  + +++   +KA    K   K R +++ K     + S R  QK +  R   K 
Sbjct: 397 QRKDDSTWNSEVMMRVQKART--KCARKSRSKEKKKEKDICSSSKRRFQKNIHRRG--KP 452

Query: 292 KDETVDFQAPLLPVTCGGVKGILHKEKLEQGTLAKCIQTEDGKWFTPMEFEIKGGYARSK 351
           K +TVDF    LPVTCG  KGIL+K+K++ G+  KCI+ EDG W TP EFE++G    +K
Sbjct: 453 KSDTVDFHCSKLPVTCGEAKGILYKKKMKHGSSVKCIRNEDGTWLTPNEFEVEGKGRNAK 512

Query: 352 NWRLSVRCGGWPLRRLMEEGSLPNPPRIYYRNKKRILKSQNNSSVDPCMRNLDECEVCRD 411
           NW+ ++RC G  L  L++                               +N DECEVC  
Sbjct: 513 NWKRNIRCEGMTLGELLKR------------------------------KNSDECEVCCQ 542

Query: 412 GGELFCCDTCSRVFHEDCHIPPVESEKTPWNCIFCRMKESPGSQQCCQESEVLERQMCPE 471
           GG+L CC TC RVFHEDCHIPPVE+++  W+C FCRMK S GSQQC   S+ LERQM P+
Sbjct: 543 GGQLLCCGTCPRVFHEDCHIPPVEAKRMLWSCTFCRMKRSSGSQQCHHVSKTLERQMQPQ 602

Query: 472 EQLKCEFLLLKVYCCSESSFFAKIPYYYYIREACQGLKEPMWLDKIKKRLNEHGYPQVEG 531
           +QL                          IR+  +  +E MWLD +K+RL    Y  V  
Sbjct: 603 DQL--------------------------IRDYGEPFQEAMWLDLVKERLITEMY-TVAW 635

Query: 532 FVQDMRLIFQNHRASYKYKDFGQMGLRLEAEFEKDFKEVFAIQETN 577
           FV+DMRL+F+NH+  YK  DFGQ+GL LEAEFEKD K+V    E N
Sbjct: 636 FVRDMRLMFRNHKTFYKASDFGQVGLDLEAEFEKDLKDVLGFHEAN 681



 Score =  119 bits (298), Expect = 8e-27
 Identities = 56/109 (51%), Positives = 82/109 (75%), Gaps = 5/109 (4%)

Query: 37  LFTEDQDVDEGLVYDTVFKHFKRHKLEISNAIKKTFPFLEGLRDRELITNKMFEDSEDSC 96
           +FT  + ++E L     F+HF   KL I+ AI K FPF EGL D  +IT +M+ +S ++C
Sbjct: 1   MFTMTRAMEEAL-----FQHFMHQKLGIAYAIHKPFPFFEGLLDNSIITKRMYMESLEAC 55

Query: 97  RNLVPVQRVVYNVLSELEKTFNLSVLEALFSEVNMQEYPDLIHIYKSFK 145
           RNL+PV RVV+N+L++LE+TFNLS+L  LFS++N++EYP+L+ IY+SFK
Sbjct: 56  RNLIPVSRVVHNILTQLERTFNLSLLVTLFSQINLREYPNLVTIYRSFK 104


>gi|190343008 SP110 nuclear body protein isoform b [Homo sapiens]
          Length = 549

 Score =  119 bits (298), Expect = 8e-27
 Identities = 56/109 (51%), Positives = 82/109 (75%), Gaps = 5/109 (4%)

Query: 37  LFTEDQDVDEGLVYDTVFKHFKRHKLEISNAIKKTFPFLEGLRDRELITNKMFEDSEDSC 96
           +FT  + ++E L     F+HF   KL I+ AI K FPF EGL D  +IT +M+ +S ++C
Sbjct: 1   MFTMTRAMEEAL-----FQHFMHQKLGIAYAIHKPFPFFEGLLDNSIITKRMYMESLEAC 55

Query: 97  RNLVPVQRVVYNVLSELEKTFNLSVLEALFSEVNMQEYPDLIHIYKSFK 145
           RNL+PV RVV+N+L++LE+TFNLS+L  LFS++N++EYP+L+ IY+SFK
Sbjct: 56  RNLIPVSRVVHNILTQLERTFNLSLLVTLFSQINLREYPNLVTIYRSFK 104



 Score =  118 bits (296), Expect = 1e-26
 Identities = 78/220 (35%), Positives = 112/220 (50%), Gaps = 17/220 (7%)

Query: 182 EARKESDQACGKMDTVDIANNSTLGK-----PKRKRRKKKG-----HGWSRMGTRTQKNN 231
           +AR E  +     + +D  +    GK     P   RR  +G     HG         K  
Sbjct: 337 KARTECARKSRSEEIIDGTSEMNEGKRSQKTPSTPRRVTQGAASPGHGIQEKLQVVDKVT 396

Query: 232 QQNDNSKADGQLVSSEKKANMNLKDLSKIRGRKRGKPGTHFTQSDRAPQKRVRSRASRKH 291
           Q+ D+S  + +++   +KA    K   K R +++ K     + S R  QK +  R   K 
Sbjct: 397 QRKDDSTWNSEVMMRVQKART--KCARKSRSKEKKKEKDICSSSKRRFQKNIHRRG--KP 452

Query: 292 KDETVDFQAPLLPVTCGGVKGILHKEKLEQGTLAKCIQTEDGKWFTPMEFEIKGGYARSK 351
           K +TVDF    LPVTCG  KGIL+K+K++ G+  KCI+ EDG W TP EFE++G    +K
Sbjct: 453 KSDTVDFHCSKLPVTCGEAKGILYKKKMKHGSSVKCIRNEDGTWLTPNEFEVEGKGRNAK 512

Query: 352 NWRLSVRCGGWPLRRLMEEGSLPNPPRIYYRNKKRILKSQ 391
           NW+ ++RC G  L  L++ G L  PPRI   N KR L S+
Sbjct: 513 NWKRNIRCEGMTLGELLKSGLLLCPPRI---NLKRELNSK 549


>gi|52487277 SP140 nuclear body protein isoform 2 [Homo sapiens]
          Length = 172

 Score =  117 bits (294), Expect = 2e-26
 Identities = 57/107 (53%), Positives = 80/107 (74%)

Query: 40  EDQDVDEGLVYDTVFKHFKRHKLEISNAIKKTFPFLEGLRDRELITNKMFEDSEDSCRNL 99
           E Q++ E +  + +F+ F+ +K+EI++AI + FPFL GLRDR  I+ +M+E  +++ RNL
Sbjct: 29  EGQNLQEQVCPEPIFRFFRENKVEIASAITRPFPFLMGLRDRSFISEQMYEHFQEAFRNL 88

Query: 100 VPVQRVVYNVLSELEKTFNLSVLEALFSEVNMQEYPDLIHIYKSFKN 146
           VPV RV+Y VLSELEKTF  S LEALFS +N+  YPDL  IY+SF+N
Sbjct: 89  VPVTRVMYCVLSELEKTFGWSHLEALFSRINLMAYPDLNEIYRSFQN 135


>gi|74027251 tripartite motif-containing 33 protein isoform beta [Homo
            sapiens]
          Length = 1110

 Score =  106 bits (265), Expect = 5e-23
 Identities = 90/292 (30%), Positives = 130/292 (44%), Gaps = 43/292 (14%)

Query: 308  GGVKGILHKEKLEQGTLAKCIQTEDGKWFTP-------MEFEIKG-----GYARSKNWRL 355
            GGVK    +EK E G  + C+ +      TP       +E E+        + + +   +
Sbjct: 790  GGVK----QEKTEDGRRSACMLSSPESSLTPPLSTNLHLESELDALASLENHVKIEPADM 845

Query: 356  SVRCGGWPLRRLMEEGSLPNPPRIYYRNKKRILKSQNNSSVDPCMRNLDECEVCRDGGEL 415
            +  C    L  L+   S   P R       RI    NN   DP   N D C VC++GG+L
Sbjct: 846  NESCKQSGLSSLVNGKS---PIRSLMHRSARIGGDGNNKDDDP---NEDWCAVCQNGGDL 899

Query: 416  FCCDTCSRVFHEDCHIPPVES-EKTPWNCIFCRMKESPGSQQCCQESEVLER-----QMC 469
             CC+ C +VFH  CH+P + S     W C FCR    P  +  C   +  ++      + 
Sbjct: 900  LCCEKCPKVFHLTCHVPTLLSFPSGDWICTFCRDIGKPEVEYDCDNLQHSKKGKTAQGLS 959

Query: 470  PEEQLKCEFLLLKVYCCSESSFF-----AKIPYYYYIREACQGLKEPMWLDKIKKRL--- 521
            P +Q KCE LLL +YC   S  F     A IP YY I      +K+PM L  +KK+L   
Sbjct: 960  PVDQRKCERLLLYLYCHELSIEFQEPVPASIPNYYKI------IKKPMDLSTVKKKLQKK 1013

Query: 522  NEHGYPQVEGFVQDMRLIFQN-HRASYKYKDFGQMGLRLEAEFEKDFKEVFA 572
            +   Y   + FV D+RLIF+N  R +    +  Q G  +   FE    E+++
Sbjct: 1014 HSQHYQIPDDFVADVRLIFKNCERFNEADSEVAQAGKAVALYFEDKLTEIYS 1065


>gi|74027249 tripartite motif-containing 33 protein isoform alpha
            [Homo sapiens]
          Length = 1127

 Score =  103 bits (257), Expect = 4e-22
 Identities = 90/296 (30%), Positives = 131/296 (44%), Gaps = 49/296 (16%)

Query: 308  GGVKGILHKEKLEQGTLAKCIQTEDGKWFTP-------MEFEIKG-----GYARSKNWRL 355
            GGVK    +EK E G  + C+ +      TP       +E E+        + + +   +
Sbjct: 790  GGVK----QEKTEDGRRSACMLSSPESSLTPPLSTNLHLESELDALASLENHVKIEPADM 845

Query: 356  SVRCGGWPLRRLMEEGSLPNPPRIYYRNKKRILKSQNNSSVDPCMRNLDECEVCRDGGEL 415
            +  C    L  L+   S   P R       RI    NN   DP   N D C VC++GG+L
Sbjct: 846  NESCKQSGLSSLVNGKS---PIRSLMHRSARIGGDGNNKDDDP---NEDWCAVCQNGGDL 899

Query: 416  FCCDTCSRVFHEDCHIPPVES-EKTPWNCIFCRMKESPGSQQCCQESEVLER-----QMC 469
             CC+ C +VFH  CH+P + S     W C FCR    P  +  C   +  ++      + 
Sbjct: 900  LCCEKCPKVFHLTCHVPTLLSFPSGDWICTFCRDIGKPEVEYDCDNLQHSKKGKTAQGLS 959

Query: 470  PEEQLKCEFLLLKVYCCSESSFF-----AKIPYYYYIREACQGLKEPMWLDKIKKRL--- 521
            P +Q KCE LLL +YC   S  F     A IP YY I      +K+PM L  +KK+L   
Sbjct: 960  PVDQRKCERLLLYLYCHELSIEFQEPVPASIPNYYKI------IKKPMDLSTVKKKLQKK 1013

Query: 522  NEHGYPQVEGFVQDMRLIFQN-------HRASYKYKDFGQMGLRLEAEFEKDFKEV 570
            +   Y   + FV D+RLIF+N        +    Y D  ++ L+ ++E  +  K V
Sbjct: 1014 HSQHYQIPDDFVADVRLIFKNCERFNEMMKVVQVYADTQEINLKADSEVAQAGKAV 1069


>gi|47419911 transcriptional intermediary factor 1 alpha isoform a
            [Homo sapiens]
          Length = 1050

 Score =  102 bits (255), Expect = 7e-22
 Identities = 71/188 (37%), Positives = 94/188 (50%), Gaps = 25/188 (13%)

Query: 402  NLDECEVCRDGGELFCCDTCSRVFHEDCHIPPVES-EKTPWNCIFCRMKESPGSQQCC-- 458
            N D C VC++GGEL CC+ C +VFH  CH+P + +     W C FCR    P  +  C  
Sbjct: 825  NEDWCAVCQNGGELLCCEKCPKVFHLSCHVPTLTNFPSGEWICTFCRDLSKPEVEYDCDA 884

Query: 459  ----QESEVLER--QMCPEEQLKCEFLLLKVYCCSESSFF-----AKIPYYYYIREACQG 507
                 E +  E   ++ P ++ KCE LLL +YC   S  F       +P YY I      
Sbjct: 885  PSHNSEKKKTEGLVKLTPIDKRKCERLLLFLYCHEMSLAFQDPVPLTVPDYYKI------ 938

Query: 508  LKEPMWLDKIKKRLNE--HGYPQVEGFVQDMRLIFQNHRASYKYKD--FGQMGLRLEAEF 563
            +K PM L  IKKRL E    Y + E FV D RLIFQN  A +   D      G++LE  F
Sbjct: 939  IKNPMDLSTIKKRLQEDYSMYSKPEDFVADFRLIFQN-CAEFNEPDSEVANAGIKLENYF 997

Query: 564  EKDFKEVF 571
            E+  K ++
Sbjct: 998  EELLKNLY 1005


>gi|47419909 transcriptional intermediary factor 1 alpha isoform b
           [Homo sapiens]
          Length = 1016

 Score =  102 bits (255), Expect = 7e-22
 Identities = 71/188 (37%), Positives = 94/188 (50%), Gaps = 25/188 (13%)

Query: 402 NLDECEVCRDGGELFCCDTCSRVFHEDCHIPPVES-EKTPWNCIFCRMKESPGSQQCC-- 458
           N D C VC++GGEL CC+ C +VFH  CH+P + +     W C FCR    P  +  C  
Sbjct: 791 NEDWCAVCQNGGELLCCEKCPKVFHLSCHVPTLTNFPSGEWICTFCRDLSKPEVEYDCDA 850

Query: 459 ----QESEVLER--QMCPEEQLKCEFLLLKVYCCSESSFF-----AKIPYYYYIREACQG 507
                E +  E   ++ P ++ KCE LLL +YC   S  F       +P YY I      
Sbjct: 851 PSHNSEKKKTEGLVKLTPIDKRKCERLLLFLYCHEMSLAFQDPVPLTVPDYYKI------ 904

Query: 508 LKEPMWLDKIKKRLNE--HGYPQVEGFVQDMRLIFQNHRASYKYKD--FGQMGLRLEAEF 563
           +K PM L  IKKRL E    Y + E FV D RLIFQN  A +   D      G++LE  F
Sbjct: 905 IKNPMDLSTIKKRLQEDYSMYSKPEDFVADFRLIFQN-CAEFNEPDSEVANAGIKLENYF 963

Query: 564 EKDFKEVF 571
           E+  K ++
Sbjct: 964 EELLKNLY 971


>gi|209977097 tripartite motif-containing 66 [Homo sapiens]
          Length = 1216

 Score = 90.1 bits (222), Expect = 5e-18
 Identities = 61/183 (33%), Positives = 87/183 (47%), Gaps = 12/183 (6%)

Query: 400  MRNLDECEVCRDGGELFCCDTCSRVFHEDCHIPPVES-EKTPWNCIFCRMKESPGSQQCC 458
            + N D C VC +GGEL CCD C +VFH  CH+P + S     W C  CR    P  +  C
Sbjct: 967  IENEDFCAVCLNGGELLCCDRCPKVFHLSCHVPALLSFPGGEWVCTLCRSLTQPEMEYDC 1026

Query: 459  QESEVLERQMCPE------EQLKCEFLLLKVYCCSESSFFAKIPYYYYIREACQGLKEPM 512
            + +   +  M         +Q KCE L+L + CC+  S     P     R   Q +K PM
Sbjct: 1027 ENACYNQPGMRASPGLSMYDQKKCEKLVLSL-CCNNLSLPFHEPVSPLARHYYQIIKRPM 1085

Query: 513  WLDKIKKRLNEHG---YPQVEGFVQDMRLIFQN-HRASYKYKDFGQMGLRLEAEFEKDFK 568
             L  I+++L +     Y   E  V D+RL+F N  + +Y   +  + G  LE  FE   K
Sbjct: 1086 DLSIIRRKLQKKDPAHYTTPEEVVSDVRLMFWNCAKFNYPDSEVAEAGRCLEVFFEGWLK 1145

Query: 569  EVF 571
            E++
Sbjct: 1146 EIY 1148


>gi|4557291 autoimmune regulator isoform 1 [Homo sapiens]
          Length = 545

 Score = 79.3 bits (194), Expect = 9e-15
 Identities = 56/160 (35%), Positives = 74/160 (46%), Gaps = 34/160 (21%)

Query: 303 LPVTCGGVKGILHKEKLEQGTLAKCIQTEDGKWFTPMEFEIKGG-------------YAR 349
           +P   G V+GIL ++  E G   KCIQ   G+++TP +FE  G                R
Sbjct: 199 VPGARGAVEGILIQQVFESGGSKKCIQV-GGEFYTPSKFEDSGSGKNKARSSSGPKPLVR 257

Query: 350 SKNWRLSVRCGGWPLRRLMEEGSLPNPPRIYYRNKKRILKSQNNSSVDPCM--RNLDECE 407
           +K  + +   GG    RL ++GS+P P  +                 DP +  +N DEC 
Sbjct: 258 AKGAQGAAPGGGEA--RLGQQGSVPAPLAL---------------PSDPQLHQKNEDECA 300

Query: 408 VCRDGGELFCCDTCSRVFHEDCHIPPV-ESEKTPWNCIFC 446
           VCRDGGEL CCD C R FH  C  PP+ E     W C  C
Sbjct: 301 VCRDGGELICCDGCPRAFHLACLSPPLREIPSGTWRCSSC 340



 Score = 34.3 bits (77), Expect = 0.32
 Identities = 16/42 (38%), Positives = 20/42 (47%), Gaps = 2/42 (4%)

Query: 406 CEVCRDGGELFCCDTCSRVFHEDCHIPPVESEKTPWNCIFCR 447
           C VC DG ++  C  C+  FH  CH P   S   P   + CR
Sbjct: 434 CGVCGDGTDVLRCTHCAAAFHWRCHFPAGTSR--PGTGLRCR 473


>gi|4557293 autoimmune regulator isoform 2 [Homo sapiens]
          Length = 348

 Score = 63.5 bits (153), Expect = 5e-10
 Identities = 27/49 (55%), Positives = 29/49 (59%), Gaps = 1/49 (2%)

Query: 399 CMRNLDECEVCRDGGELFCCDTCSRVFHEDCHIPPV-ESEKTPWNCIFC 446
           C +N DEC VCRDGGEL CCD C R FH  C  PP+ E     W C  C
Sbjct: 95  CQKNEDECAVCRDGGELICCDGCPRAFHLACLSPPLREIPSGTWRCSSC 143



 Score = 34.3 bits (77), Expect = 0.32
 Identities = 16/42 (38%), Positives = 20/42 (47%), Gaps = 2/42 (4%)

Query: 406 CEVCRDGGELFCCDTCSRVFHEDCHIPPVESEKTPWNCIFCR 447
           C VC DG ++  C  C+  FH  CH P   S   P   + CR
Sbjct: 237 CGVCGDGTDVLRCTHCAAAFHWRCHFPAGTSR--PGTGLRCR 276


>gi|38016945 deformed epidermal autoregulatory factor 1 [Homo
           sapiens]
          Length = 565

 Score = 63.2 bits (152), Expect = 6e-10
 Identities = 31/74 (41%), Positives = 46/74 (62%), Gaps = 2/74 (2%)

Query: 303 LPVTCGGVKGILHKEKLEQGTLAKCIQTEDGKWFTPMEFEIKGGYARSKNWRLSVRCGGW 362
           LPV C  + G L+K +L  G   +CI+  +  W++P EFE   G A SK+W+ S+R  G 
Sbjct: 203 LPVRCRNISGTLYKNRLGSGGRGRCIKQGEN-WYSPTEFEAMAGRASSKDWKRSIRYAGR 261

Query: 363 PLRRLMEEGSLPNP 376
           PL+ L+++G L NP
Sbjct: 262 PLQCLIQDGIL-NP 274


>gi|5032179 tripartite motif-containing 28 protein [Homo sapiens]
          Length = 835

 Score = 62.8 bits (151), Expect = 8e-10
 Identities = 49/178 (27%), Positives = 77/178 (43%), Gaps = 17/178 (9%)

Query: 406 CEVCRDGGELFCCDTCSRVFHEDCHIPPVES-EKTPWNCIFCR----MKESPGSQQC-CQ 459
           C VC+  G+L  C+ C   FH DCH+P ++      W+C  C     +KE  GS      
Sbjct: 628 CRVCQKPGDLVMCNQCEFCFHLDCHLPALQDVPGEEWSCSLCHVLPDLKEEDGSLSLDGA 687

Query: 460 ESEVLERQMCPEEQLKCEFLLLKVYCCSESSFFAKIPYYYYIREACQGLKEP---MWLDK 516
           +S  +  ++ P  Q KCE +LL ++C          P +    ++   L +P   + L  
Sbjct: 688 DSTGVVAKLSPANQRKCERVLLALFCHEPCR-----PLHQLATDSTFSLDQPGGTLDLTL 742

Query: 517 IKKRLNEH---GYPQVEGFVQDMRLIFQNHRASYKYKDFGQMGLRLEAEFEKDFKEVF 571
           I+ RL E     Y   + F QD+  +F+      + K   Q  + L+  FE    E F
Sbjct: 743 IRARLQEKLSPPYSSPQEFAQDVGRMFKQFNKLTEDKADVQSIIGLQRFFETRMNEAF 800


>gi|38788260 bromodomain PHD finger transcription factor isoform 2
           [Homo sapiens]
          Length = 2903

 Score = 57.0 bits (136), Expect = 5e-08
 Identities = 24/58 (41%), Positives = 31/58 (53%), Gaps = 1/58 (1%)

Query: 404 DECEVCRDGGELFCCDTCSRVFHEDCHIPPVES-EKTPWNCIFCRMKESPGSQQCCQE 460
           D C VC   G+L CC+TCS V+H +C  PP+E   +  W C  C   + PG   C  E
Sbjct: 391 DHCRVCHKLGDLLCCETCSAVYHLECVKPPLEEVPEDEWQCEVCVAHKVPGVTDCVAE 448



 Score = 31.2 bits (69), Expect = 2.7
 Identities = 28/84 (33%), Positives = 39/84 (46%), Gaps = 9/84 (10%)

Query: 496  PYYYYIREACQGLKEPMWLDKIKKRLNEHGYPQVEGFVQDMRLIFQNHRASYKYKD--FG 553
            P YY +      +KEPM L  +++R+    Y ++  FV DM  IF N R  Y   D  F 
Sbjct: 2819 PDYYGV------IKEPMDLATMEERVQRRYYEKLTEFVADMTKIFDNCR-YYNPSDSPFY 2871

Query: 554  QMGLRLEAEFEKDFKEVFAIQETN 577
            Q    LE+ F +  K   A +  N
Sbjct: 2872 QCAEVLESFFVQKLKGFKASRSHN 2895


>gi|38788274 bromodomain PHD finger transcription factor isoform 1
           [Homo sapiens]
          Length = 2920

 Score = 57.0 bits (136), Expect = 5e-08
 Identities = 24/58 (41%), Positives = 31/58 (53%), Gaps = 1/58 (1%)

Query: 404 DECEVCRDGGELFCCDTCSRVFHEDCHIPPVES-EKTPWNCIFCRMKESPGSQQCCQE 460
           D C VC   G+L CC+TCS V+H +C  PP+E   +  W C  C   + PG   C  E
Sbjct: 391 DHCRVCHKLGDLLCCETCSAVYHLECVKPPLEEVPEDEWQCEVCVAHKVPGVTDCVAE 448



 Score = 31.2 bits (69), Expect = 2.7
 Identities = 28/84 (33%), Positives = 39/84 (46%), Gaps = 9/84 (10%)

Query: 496  PYYYYIREACQGLKEPMWLDKIKKRLNEHGYPQVEGFVQDMRLIFQNHRASYKYKD--FG 553
            P YY +      +KEPM L  +++R+    Y ++  FV DM  IF N R  Y   D  F 
Sbjct: 2836 PDYYGV------IKEPMDLATMEERVQRRYYEKLTEFVADMTKIFDNCR-YYNPSDSPFY 2888

Query: 554  QMGLRLEAEFEKDFKEVFAIQETN 577
            Q    LE+ F +  K   A +  N
Sbjct: 2889 QCAEVLESFFVQKLKGFKASRSHN 2912


>gi|75677357 PHD finger protein 12 isoform 1 [Homo sapiens]
          Length = 1004

 Score = 54.7 bits (130), Expect = 2e-07
 Identities = 25/76 (32%), Positives = 35/76 (46%), Gaps = 3/76 (3%)

Query: 384 KKRILKSQNNSSVDPCMRNLDECEVCRDGGELFCCDTCSRVFHEDCHIPPVESEKTP--- 440
           +KR  K +          N D C+ C++GG+L CCD C   FH  C  PP+  E  P   
Sbjct: 37  EKRSRKPEKEPRRSGRATNHDSCDSCKEGGDLLCCDHCPAAFHLQCCNPPLSEEMLPPGE 96

Query: 441 WNCIFCRMKESPGSQQ 456
           W C  C ++     Q+
Sbjct: 97  WMCHRCTVRRKKREQK 112


>gi|30842829 PHD finger protein 12 isoform 2 [Homo sapiens]
          Length = 704

 Score = 54.7 bits (130), Expect = 2e-07
 Identities = 25/76 (32%), Positives = 35/76 (46%), Gaps = 3/76 (3%)

Query: 384 KKRILKSQNNSSVDPCMRNLDECEVCRDGGELFCCDTCSRVFHEDCHIPPVESEKTP--- 440
           +KR  K +          N D C+ C++GG+L CCD C   FH  C  PP+  E  P   
Sbjct: 37  EKRSRKPEKEPRRSGRATNHDSCDSCKEGGDLLCCDHCPAAFHLQCCNPPLSEEMLPPGE 96

Query: 441 WNCIFCRMKESPGSQQ 456
           W C  C ++     Q+
Sbjct: 97  WMCHRCTVRRKKREQK 112


>gi|156546910 BRAF35/HDAC2 complex isoform b [Homo sapiens]
          Length = 634

 Score = 52.8 bits (125), Expect = 9e-07
 Identities = 23/45 (51%), Positives = 29/45 (64%), Gaps = 1/45 (2%)

Query: 404 DECEVCRDGGELFCCDTCSRVFHEDCHIPPVES-EKTPWNCIFCR 447
           D C VCR  G+L  CDTCSRV+H DC  PP+++  K  W C  C+
Sbjct: 443 DFCSVCRKSGQLLMCDTCSRVYHLDCLDPPLKTIPKGMWICPRCQ 487


>gi|156546894 BRAF35/HDAC2 complex isoform a [Homo sapiens]
          Length = 680

 Score = 52.8 bits (125), Expect = 9e-07
 Identities = 23/45 (51%), Positives = 29/45 (64%), Gaps = 1/45 (2%)

Query: 404 DECEVCRDGGELFCCDTCSRVFHEDCHIPPVES-EKTPWNCIFCR 447
           D C VCR  G+L  CDTCSRV+H DC  PP+++  K  W C  C+
Sbjct: 489 DFCSVCRKSGQLLMCDTCSRVYHLDCLDPPLKTIPKGMWICPRCQ 533


>gi|51599156 chromodomain helicase DNA binding protein 4 [Homo
           sapiens]
          Length = 1912

 Score = 51.2 bits (121), Expect = 3e-06
 Identities = 23/56 (41%), Positives = 29/56 (51%), Gaps = 1/56 (1%)

Query: 402 NLDECEVCRDGGELFCCDTCSRVFHEDCHIPPV-ESEKTPWNCIFCRMKESPGSQQ 456
           +++ C VC+DGGEL CCDTC   +H  C  PP+ E     W C  C      G  Q
Sbjct: 448 HMEFCRVCKDGGELLCCDTCPSSYHIHCLNPPLPEIPNGEWLCPRCTCPALKGKVQ 503



 Score = 49.3 bits (116), Expect = 1e-05
 Identities = 20/44 (45%), Positives = 27/44 (61%), Gaps = 1/44 (2%)

Query: 404 DECEVCRDGGELFCCDTCSRVFHEDCHIPPVE-SEKTPWNCIFC 446
           D CEVC+ GGE+  CDTC R +H  C  P +E + +  W+C  C
Sbjct: 371 DYCEVCQQGGEIILCDTCPRAYHMVCLDPDMEKAPEGKWSCPHC 414


>gi|24308089 chromodomain helicase DNA binding protein 5 [Homo
           sapiens]
          Length = 1954

 Score = 51.2 bits (121), Expect = 3e-06
 Identities = 34/96 (35%), Positives = 46/96 (47%), Gaps = 13/96 (13%)

Query: 382 RNKKRILKSQNNSSVDPCMRNLDECEVCRDGGELFCCDTCSRVFHEDCHIPPVESEKTP- 440
           R KK+ +   +    D    + D CEVC+ GGE+  CDTC R +H  C  P  E EK P 
Sbjct: 326 RRKKKRIDDGDGYETD----HQDYCEVCQQGGEIILCDTCPRAYHLVCLDP--ELEKAPE 379

Query: 441 --WNCIFCRMKESPGSQ-QCCQESEVLERQMCPEEQ 473
             W+C  C   E  G Q +   + +  E   C EE+
Sbjct: 380 GKWSCPHC---EKEGIQWEPKDDDDEEEEGGCEEEE 412



 Score = 49.3 bits (116), Expect = 1e-05
 Identities = 22/56 (39%), Positives = 28/56 (50%), Gaps = 1/56 (1%)

Query: 402 NLDECEVCRDGGELFCCDTCSRVFHEDCHIPPV-ESEKTPWNCIFCRMKESPGSQQ 456
           +++ C VC+DGGEL CCD C   +H  C  PP+ E     W C  C      G  Q
Sbjct: 415 HMEFCRVCKDGGELLCCDACPSSYHLHCLNPPLPEIPNGEWLCPRCTCPPLKGKVQ 470


>gi|52630326 chromodomain helicase DNA binding protein 3 isoform 1
           [Homo sapiens]
          Length = 2000

 Score = 49.3 bits (116), Expect = 1e-05
 Identities = 24/60 (40%), Positives = 33/60 (55%), Gaps = 4/60 (6%)

Query: 404 DECEVCRDGGELFCCDTCSRVFHEDCHIPPVE-SEKTPWNCIFCRMKESPGSQQCCQESE 462
           D CEVC+ GGE+  CDTC R +H  C  P ++ + +  W+C  C   E  G Q   +E E
Sbjct: 380 DYCEVCQQGGEIILCDTCPRAYHLVCLDPELDRAPEGKWSCPHC---EKEGVQWEAKEEE 436



 Score = 47.4 bits (111), Expect = 4e-05
 Identities = 19/46 (41%), Positives = 26/46 (56%), Gaps = 1/46 (2%)

Query: 402 NLDECEVCRDGGELFCCDTCSRVFHEDCHIPPV-ESEKTPWNCIFC 446
           +++ C VC+DGGEL CCD C   +H  C  PP+ +     W C  C
Sbjct: 455 HMEYCRVCKDGGELLCCDACISSYHIHCLNPPLPDIPNGEWLCPRC 500


>gi|52630322 chromodomain helicase DNA binding protein 3 isoform 2
           [Homo sapiens]
          Length = 1966

 Score = 49.3 bits (116), Expect = 1e-05
 Identities = 24/60 (40%), Positives = 33/60 (55%), Gaps = 4/60 (6%)

Query: 404 DECEVCRDGGELFCCDTCSRVFHEDCHIPPVE-SEKTPWNCIFCRMKESPGSQQCCQESE 462
           D CEVC+ GGE+  CDTC R +H  C  P ++ + +  W+C  C   E  G Q   +E E
Sbjct: 380 DYCEVCQQGGEIILCDTCPRAYHLVCLDPELDRAPEGKWSCPHC---EKEGVQWEAKEEE 436



 Score = 47.4 bits (111), Expect = 4e-05
 Identities = 19/46 (41%), Positives = 26/46 (56%), Gaps = 1/46 (2%)

Query: 402 NLDECEVCRDGGELFCCDTCSRVFHEDCHIPPV-ESEKTPWNCIFC 446
           +++ C VC+DGGEL CCD C   +H  C  PP+ +     W C  C
Sbjct: 455 HMEYCRVCKDGGELLCCDACISSYHIHCLNPPLPDIPNGEWLCPRC 500


>gi|158420731 chromodomain helicase DNA binding protein 3 isoform 3
           [Homo sapiens]
          Length = 2059

 Score = 49.3 bits (116), Expect = 1e-05
 Identities = 24/60 (40%), Positives = 33/60 (55%), Gaps = 4/60 (6%)

Query: 404 DECEVCRDGGELFCCDTCSRVFHEDCHIPPVE-SEKTPWNCIFCRMKESPGSQQCCQESE 462
           D CEVC+ GGE+  CDTC R +H  C  P ++ + +  W+C  C   E  G Q   +E E
Sbjct: 439 DYCEVCQQGGEIILCDTCPRAYHLVCLDPELDRAPEGKWSCPHC---EKEGVQWEAKEEE 495



 Score = 47.4 bits (111), Expect = 4e-05
 Identities = 19/46 (41%), Positives = 26/46 (56%), Gaps = 1/46 (2%)

Query: 402 NLDECEVCRDGGELFCCDTCSRVFHEDCHIPPV-ESEKTPWNCIFC 446
           +++ C VC+DGGEL CCD C   +H  C  PP+ +     W C  C
Sbjct: 514 HMEYCRVCKDGGELLCCDACISSYHIHCLNPPLPDIPNGEWLCPRC 559


>gi|34335264 zinc finger, MYND-type containing 8 isoform c [Homo
           sapiens]
          Length = 1135

 Score = 47.4 bits (111), Expect = 4e-05
 Identities = 42/163 (25%), Positives = 67/163 (41%), Gaps = 10/163 (6%)

Query: 382 RNKKRILKSQNNSSVDPCMRNLDECEVCRDGGELFCCDTCSRVFHEDCHIPPVESEKTPW 441
           + KK  L + NN   D   RN   C VC   G++ CC+ C RV+H  C +      +  W
Sbjct: 64  KKKKPGLLNSNNKEQDG--RNDFYCWVCHREGQVLCCELCPRVYHAKC-LRLTSEPEGDW 120

Query: 442 NCIFCRMKESPGSQQCCQESEVLERQMCPEEQLK--CEFLLLKVYCCSESSFFAKIPYYY 499
            C  C       +   C E++     M   EQL    +F + K+      +F   +P   
Sbjct: 121 FCPECEKI----TVAECIETQSKAMTMLTIEQLSYLLKFAIQKMKQPGTDAFQKPVPLEQ 176

Query: 500 YIREACQGLKEPMWLDKIKKRLNEHGYPQVEGFVQDMRLIFQN 542
           +  +  + +  PM L  ++K   +  Y   E F+ D + I  N
Sbjct: 177 H-PDYAEYIFHPMDLCTLEKNAKKKMYGCTEAFLADAKWILHN 218


>gi|27477095 nuclear receptor binding SET domain protein 1 isoform a
            [Homo sapiens]
          Length = 2427

 Score = 45.4 bits (106), Expect = 1e-04
 Identities = 18/51 (35%), Positives = 27/51 (52%), Gaps = 2/51 (3%)

Query: 402  NLDECEVCRDGGELFCCDTCSRVFHEDCHIPPVESEKTPWNCIFCRMKESP 452
            N+  C VC +GG L CCD+C   FH +C    ++  +  W C  C+  + P
Sbjct: 1437 NVSWCFVCSEGGSLLCCDSCPAAFHREC--LNIDIPEGNWYCNDCKAGKKP 1485



 Score = 34.7 bits (78), Expect = 0.25
 Identities = 19/60 (31%), Positives = 27/60 (45%), Gaps = 6/60 (10%)

Query: 404  DECEVCRDGGELFCCDT--CSRVFHEDC---HIPPVESEKTPWN-CIFCRMKESPGSQQC 457
            DEC  C D G+L  C    C +V+H DC      P    + PW+ C  C  + +   + C
Sbjct: 1850 DECFSCGDAGQLVSCKKPGCPKVYHADCLNLTKRPAGKWECPWHQCDICGKEAASFCEMC 1909


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.317    0.134    0.404 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 23,432,482
Number of Sequences: 37866
Number of extensions: 1125479
Number of successful extensions: 4813
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 96
Number of HSP's successfully gapped in prelim test: 173
Number of HSP's that attempted gapping in prelim test: 4344
Number of HSP's gapped (non-prelim): 545
length of query: 580
length of database: 18,247,518
effective HSP length: 108
effective length of query: 472
effective length of database: 14,157,990
effective search space: 6682571280
effective search space used: 6682571280
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 65 (29.6 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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