BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|55956910 meningioma 1 [Homo sapiens] (1320 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|55956910 meningioma 1 [Homo sapiens] 2762 0.0 gi|4502951 collagen type III alpha 1 preproprotein [Homo sapiens] 109 2e-23 gi|15890086 type IV collagen alpha 5 isoform 2 precursor [Homo s... 105 3e-22 gi|4502955 type IV collagen alpha 5 isoform 1 precursor [Homo sa... 105 3e-22 gi|15890088 type IV collagen alpha 5 isoform 3 precursor [Homo s... 105 3e-22 gi|40068466 AT rich interactive domain 1B (SWI1-like) isoform 1 ... 105 4e-22 gi|110349772 alpha 1 type I collagen preproprotein [Homo sapiens] 104 6e-22 gi|21264565 AT rich interactive domain 1A isoform a [Homo sapiens] 103 1e-21 gi|21264575 AT rich interactive domain 1A isoform b [Homo sapiens] 103 1e-21 gi|111118976 collagen, type II, alpha 1 isoform 1 precursor [Hom... 102 3e-21 gi|111118974 collagen, type II, alpha 1 isoform 2 precursor [Hom... 102 3e-21 gi|111118972 collagen, type XI, alpha 2 isoform 2 preproprotein ... 97 1e-19 gi|111118968 collagen, type XI, alpha 2 isoform 3 preproprotein ... 97 1e-19 gi|111118970 collagen, type XI, alpha 2 isoform 1 preproprotein ... 97 1e-19 gi|40068462 AT rich interactive domain 1B (SWI1-like) isoform 3 ... 97 1e-19 gi|89276751 alpha 1 type V collagen preproprotein [Homo sapiens] 94 7e-19 gi|22027597 alpha 1 type XIII collagen isoform 13 [Homo sapiens] 94 7e-19 gi|22027580 alpha 1 type XIII collagen isoform 6 [Homo sapiens] 94 7e-19 gi|89363017 alpha 2 type V collagen preproprotein [Homo sapiens] 94 9e-19 gi|116256356 alpha 4 type IV collagen precursor [Homo sapiens] 93 1e-18 gi|40068464 AT rich interactive domain 1B (SWI1-like) isoform 2 ... 93 1e-18 gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo ... 92 4e-18 gi|110735435 collagen, type V, alpha 3 preproprotein [Homo sapiens] 91 6e-18 gi|194294532 alpha 1 type XIII collagen isoform 20 [Homo sapiens] 91 6e-18 gi|22027583 alpha 1 type XIII collagen isoform 7 [Homo sapiens] 91 7e-18 gi|22027565 alpha 1 type XIII collagen isoform 1 [Homo sapiens] 91 7e-18 gi|22027587 alpha 1 type XIII collagen isoform 8 [Homo sapiens] 91 7e-18 gi|239754955 PREDICTED: similar to COL22A1 protein [Homo sapiens] 91 1e-17 gi|55750053 atrophin-1 [Homo sapiens] 89 3e-17 gi|55750041 atrophin-1 [Homo sapiens] 89 3e-17 >gi|55956910 meningioma 1 [Homo sapiens] Length = 1320 Score = 2762 bits (7160), Expect = 0.0 Identities = 1320/1320 (100%), Positives = 1320/1320 (100%) Query: 1 MFGLDQFEPQVNSRNAGQGERNFNETGLSMNTHFKAPAFHTGGPPGPVDPAMSALGEPPI 60 MFGLDQFEPQVNSRNAGQGERNFNETGLSMNTHFKAPAFHTGGPPGPVDPAMSALGEPPI Sbjct: 1 MFGLDQFEPQVNSRNAGQGERNFNETGLSMNTHFKAPAFHTGGPPGPVDPAMSALGEPPI 60 Query: 61 LGMNMEPYGFHARGHSELHAGGLQAQPVHGFFGGQQPHHGHPGSHHPHQHHPHFGGNFGG 120 LGMNMEPYGFHARGHSELHAGGLQAQPVHGFFGGQQPHHGHPGSHHPHQHHPHFGGNFGG Sbjct: 61 LGMNMEPYGFHARGHSELHAGGLQAQPVHGFFGGQQPHHGHPGSHHPHQHHPHFGGNFGG 120 Query: 121 PDPGASCLHGGRLLGYGGAAGGLGSQPPFAEGYEHMAESQGPESFGPQRPGNLPDFHSSG 180 PDPGASCLHGGRLLGYGGAAGGLGSQPPFAEGYEHMAESQGPESFGPQRPGNLPDFHSSG Sbjct: 121 PDPGASCLHGGRLLGYGGAAGGLGSQPPFAEGYEHMAESQGPESFGPQRPGNLPDFHSSG 180 Query: 181 ASSHAVPAPCLPLDQSPNRAASFHGLPSSSGSDSHSLEPRRVTNQGAVDSLEYNYPGEAP 240 ASSHAVPAPCLPLDQSPNRAASFHGLPSSSGSDSHSLEPRRVTNQGAVDSLEYNYPGEAP Sbjct: 181 ASSHAVPAPCLPLDQSPNRAASFHGLPSSSGSDSHSLEPRRVTNQGAVDSLEYNYPGEAP 240 Query: 241 SGHFDMFSPSDSEGQLPHYAAGRQVPGGAFPGASAMPRAAGMVGLSKMHAQPPQQQPQQQ 300 SGHFDMFSPSDSEGQLPHYAAGRQVPGGAFPGASAMPRAAGMVGLSKMHAQPPQQQPQQQ Sbjct: 241 SGHFDMFSPSDSEGQLPHYAAGRQVPGGAFPGASAMPRAAGMVGLSKMHAQPPQQQPQQQ 300 Query: 301 QQPQQQQQQHGVFFERFSGARKMPVGLEPSVGSRHPLMQPPQQAPPPPQQQPPQQPPQQQ 360 QQPQQQQQQHGVFFERFSGARKMPVGLEPSVGSRHPLMQPPQQAPPPPQQQPPQQPPQQQ Sbjct: 301 QQPQQQQQQHGVFFERFSGARKMPVGLEPSVGSRHPLMQPPQQAPPPPQQQPPQQPPQQQ 360 Query: 361 PPPPPGLLVRQNSCPPALPRPQQGEAGTPSGGLQDGGPMLPSQHAQFEYPIHRLENRSMH 420 PPPPPGLLVRQNSCPPALPRPQQGEAGTPSGGLQDGGPMLPSQHAQFEYPIHRLENRSMH Sbjct: 361 PPPPPGLLVRQNSCPPALPRPQQGEAGTPSGGLQDGGPMLPSQHAQFEYPIHRLENRSMH 420 Query: 421 PYSEPVFSMQHPPPQQAPNQRLQHFDAPPYMNVAKRPRFDFPGSAGVDRCASWNGSMHNG 480 PYSEPVFSMQHPPPQQAPNQRLQHFDAPPYMNVAKRPRFDFPGSAGVDRCASWNGSMHNG Sbjct: 421 PYSEPVFSMQHPPPQQAPNQRLQHFDAPPYMNVAKRPRFDFPGSAGVDRCASWNGSMHNG 480 Query: 481 ALDNHLSPSAYPGLPGEFTPPVPDSFPSGPPLQHPAPDHQSLQQQQQQQQQQQQQQQQQQ 540 ALDNHLSPSAYPGLPGEFTPPVPDSFPSGPPLQHPAPDHQSLQQQQQQQQQQQQQQQQQQ Sbjct: 481 ALDNHLSPSAYPGLPGEFTPPVPDSFPSGPPLQHPAPDHQSLQQQQQQQQQQQQQQQQQQ 540 Query: 541 QQQQQQQQQQRQNAALMIKQMASRNQQQRLRQPNLAQLGHPGDVGQGGLVHGGPVGGLAQ 600 QQQQQQQQQQRQNAALMIKQMASRNQQQRLRQPNLAQLGHPGDVGQGGLVHGGPVGGLAQ Sbjct: 541 QQQQQQQQQQRQNAALMIKQMASRNQQQRLRQPNLAQLGHPGDVGQGGLVHGGPVGGLAQ 600 Query: 601 PNFEREGGSTGAGRLGTFEQQAPHLAQESAWFSGPHPPPGDLLPRRMGGSGLPADCGPHD 660 PNFEREGGSTGAGRLGTFEQQAPHLAQESAWFSGPHPPPGDLLPRRMGGSGLPADCGPHD Sbjct: 601 PNFEREGGSTGAGRLGTFEQQAPHLAQESAWFSGPHPPPGDLLPRRMGGSGLPADCGPHD 660 Query: 661 PSLAPPPPPGGSGVLFRGPLQEPMRMPGEGHVPALPSPGLQFGGSLGGLGQLQSPGAGVG 720 PSLAPPPPPGGSGVLFRGPLQEPMRMPGEGHVPALPSPGLQFGGSLGGLGQLQSPGAGVG Sbjct: 661 PSLAPPPPPGGSGVLFRGPLQEPMRMPGEGHVPALPSPGLQFGGSLGGLGQLQSPGAGVG 720 Query: 721 LPSAASERRPPPPDFATSALGGQPGFPFGAAGRQSTPHSGPGVNSPPSAGGGGGSSGGGG 780 LPSAASERRPPPPDFATSALGGQPGFPFGAAGRQSTPHSGPGVNSPPSAGGGGGSSGGGG Sbjct: 721 LPSAASERRPPPPDFATSALGGQPGFPFGAAGRQSTPHSGPGVNSPPSAGGGGGSSGGGG 780 Query: 781 GGGAYPPQPDFQPSQRTSASKLGALSLGSFNKPSSKDNLFGQSCLAALSTACQNMIASLG 840 GGGAYPPQPDFQPSQRTSASKLGALSLGSFNKPSSKDNLFGQSCLAALSTACQNMIASLG Sbjct: 781 GGGAYPPQPDFQPSQRTSASKLGALSLGSFNKPSSKDNLFGQSCLAALSTACQNMIASLG 840 Query: 841 APNLNVTFNKKNPPEGKRKLSQNETDGAAVAGNPGSDYFPGGTAPGAPGPGGPSGTSSSG 900 APNLNVTFNKKNPPEGKRKLSQNETDGAAVAGNPGSDYFPGGTAPGAPGPGGPSGTSSSG Sbjct: 841 APNLNVTFNKKNPPEGKRKLSQNETDGAAVAGNPGSDYFPGGTAPGAPGPGGPSGTSSSG 900 Query: 901 SKASGPPNPPAQGDGTSLSPNYTLESTSGNDGKPVSGGGGRGRGRRKRDSGHVSPGTFFD 960 SKASGPPNPPAQGDGTSLSPNYTLESTSGNDGKPVSGGGGRGRGRRKRDSGHVSPGTFFD Sbjct: 901 SKASGPPNPPAQGDGTSLSPNYTLESTSGNDGKPVSGGGGRGRGRRKRDSGHVSPGTFFD 960 Query: 961 KYSAAPDSGGAPGVSPGQQQASGAAVGGSSAGETRGAPTPHEKALTSPSWGKGAELLLGD 1020 KYSAAPDSGGAPGVSPGQQQASGAAVGGSSAGETRGAPTPHEKALTSPSWGKGAELLLGD Sbjct: 961 KYSAAPDSGGAPGVSPGQQQASGAAVGGSSAGETRGAPTPHEKALTSPSWGKGAELLLGD 1020 Query: 1021 QPDLIGSLDGGAKSDSSSPNVGEFASDEVSTSYANEDEVSSSSDNPQALVKASRSPLVTG 1080 QPDLIGSLDGGAKSDSSSPNVGEFASDEVSTSYANEDEVSSSSDNPQALVKASRSPLVTG Sbjct: 1021 QPDLIGSLDGGAKSDSSSPNVGEFASDEVSTSYANEDEVSSSSDNPQALVKASRSPLVTG 1080 Query: 1081 SPKLPPRGVGAGEHGPKAPPPALGLGIMSNSTSTPDSYGGGGGPGHPGTPGLEQVRTPTS 1140 SPKLPPRGVGAGEHGPKAPPPALGLGIMSNSTSTPDSYGGGGGPGHPGTPGLEQVRTPTS Sbjct: 1081 SPKLPPRGVGAGEHGPKAPPPALGLGIMSNSTSTPDSYGGGGGPGHPGTPGLEQVRTPTS 1140 Query: 1141 SSGAPPPDEIHPLEILQAQIQLQRQQFSISEDQPLGLKGGKKGECAVGASGAQNGDSELG 1200 SSGAPPPDEIHPLEILQAQIQLQRQQFSISEDQPLGLKGGKKGECAVGASGAQNGDSELG Sbjct: 1141 SSGAPPPDEIHPLEILQAQIQLQRQQFSISEDQPLGLKGGKKGECAVGASGAQNGDSELG 1200 Query: 1201 SCCSEAVKSAMSTIDLDSLMAEHSAAWYMPADKALVDSADDDKTLAPWEKAKPQNPNSKE 1260 SCCSEAVKSAMSTIDLDSLMAEHSAAWYMPADKALVDSADDDKTLAPWEKAKPQNPNSKE Sbjct: 1201 SCCSEAVKSAMSTIDLDSLMAEHSAAWYMPADKALVDSADDDKTLAPWEKAKPQNPNSKE 1260 Query: 1261 AHDLPANKASASQPGSHLQCLSVHCTDDVGDAKARASVPTWRSLHSDISNRFGTFVAALT 1320 AHDLPANKASASQPGSHLQCLSVHCTDDVGDAKARASVPTWRSLHSDISNRFGTFVAALT Sbjct: 1261 AHDLPANKASASQPGSHLQCLSVHCTDDVGDAKARASVPTWRSLHSDISNRFGTFVAALT 1320 >gi|4502951 collagen type III alpha 1 preproprotein [Homo sapiens] Length = 1466 Score = 109 bits (272), Expect = 2e-23 Identities = 219/868 (25%), Positives = 285/868 (32%), Gaps = 162/868 (18%) Query: 339 QPPQQAPPPPQQQPPQQPPQQQPPPPPGLLVRQNSCPPALPRPQQGEAGTPS-GGLQDGG 397 QPP PP Q PQ P + P PPG+ R P +P Q G G+P G+ + Sbjct: 90 QPPTAPTRPPNGQGPQGP--KGDPGPPGIPGRNGD--PGIP-GQPGSPGSPGPPGICESC 144 Query: 398 PMLPSQHAQFEYPIHRLEN----RSMHPYSEPVFSMQHPPPQQAPNQRLQHFDAPPYMNV 453 P P ++ +Y + +++ + Y P PP P H +P Sbjct: 145 PTGPQNYSP-QYDSYDVKSGVAVGGLAGYPGPA----GPPGPPGPPGTSGHPGSPGSPGY 199 Query: 454 AKRPRFDFPGSAGVDRCASWNGSMHNGALDNHLSPSAYPGLPGEFTPPVPDSF--PSGPP 511 P PG AG G++ S PG PGE P P P+G P Sbjct: 200 QGPP--GEPGQAGPSGPPGPPGAIGPSGPAGKDGESGRPGRPGERGLPGPPGIKGPAGIP 257 Query: 512 LQHPAPDHQSLQQQQQQQQQQQQQQQQQQQQQQQQQQQQRQNAALMIKQMASRNQQQRLR 571 H+ RN ++ Sbjct: 258 GFPGMKGHRGFD---------------------------------------GRNGEK--- 275 Query: 572 QPNLAQLGHPGDVGQGGLV----HGGPVGGLAQPNFEREGGSTGA-------GRLGTFEQ 620 + G PG G+ GL GP+G P G GA G G+ Q Sbjct: 276 ----GETGAPGLKGENGLPGENGAPGPMGPRGAPGERGRPGLPGAAGARGNDGARGSDGQ 331 Query: 621 QAPHLAQESAWFSGPHPPPGDLLPRRMGGS-GLPADCGP-----HDPSLAPPPPPGGSGV 674 P +A F G G++ P GS G P G H + PP PPG +G Sbjct: 332 PGPPGPPGTAGFPGSPGAKGEVGPAGSPGSNGAPGQRGEPGPQGHAGAQGPPGPPGINGS 391 Query: 675 LFRGPLQEPMRMPGEGHVPALPSPGLQFG-GSLGGLGQLQSPG--AGVGLPSAASERRPP 731 P +PG +PGL G G G +PG G G P + P Sbjct: 392 PGGKGEMGPAGIPG--------APGLMGARGPPGPAGANGAPGLRGGAGEPGKNGAKGEP 443 Query: 732 PP--DFATSALGGQPGFPFGAAGRQSTPHSGPGVNSPPSAGGGGGSSGGGGGGGAYPPQP 789 P + + + G PG G G+ +P PG N P A G G+ G G P P Sbjct: 444 GPRGERGEAGIPGVPGAK-GEDGKDGSP-GEPGANGLPGAAGERGAPGFRG-----PAGP 496 Query: 790 DFQPSQRTSASKLGALS----LGSFNKPSSKDNLFGQSCLAALSTACQNMIASLGAPNLN 845 + P ++ A + GA G+ +P +D + G + M S G P + Sbjct: 497 NGIPGEKGPAGERGAPGPAGPRGAAGEP-GRDGVPG-------GPGMRGMPGSPGGPGSD 548 Query: 846 VTFNKKNPPEGKRKLSQNETDG-AAVAGNPGSDYFPGGT-------------APGAPGPG 891 K PP + + + G + G PG FPG PG PGP Sbjct: 549 ---GKPGPPGSQGESGRPGPPGPSGPRGQPGVMGFPGPKGNDGAPGKNGERGGPGGPGPQ 605 Query: 892 GPSGTSSSGSKASGPPNPPAQ-GDGTSLSPNYTLESTSGNDGKPVSGG-----GGRGRGR 945 GP G + + GPP P GD P G G P +GG G G Sbjct: 606 GPPGKNGE-TGPQGPPGPTGPGGDKGDTGP----PGPQGLQGLPGTGGPPGENGKPGEPG 660 Query: 946 RKRDSGHVSPGTFFDKYSA-APDSGGAPGVSPGQQQASGAAVGGSSAGETRGAPTPHEKA 1004 K D+G +PG K A AP G PG++ GA G G+ P Sbjct: 661 PKGDAG--APGAPGGKGDAGAPGERGPPGLAGAPGLRGGAGPPGPEGGKGAAGP------ 712 Query: 1005 LTSPSWGKGAELLLGDQPDLIGSLDGGAKSDSSSPNVGEFASDEVSTSYANEDEVSSSSD 1064 P G L G + G G K D P G +D V Sbjct: 713 -PGPPGAAGTPGLQGMPGERGGLGSPGPKGDKGEP--GGPGADGVPGKDGPRGPTGPIGP 769 Query: 1065 NPQALVKASRSPLVTGSPKLP----PRGVGAGEHGPKAPPPALGLGIMSNSTSTPDSYGG 1120 A + G+P LP PRG GE G PP G P G Sbjct: 770 PGPAGQPGDKGE--GGAPGLPGIAGPRG-SPGERGETGPPGPAGFPGAPGQNGEPGGKGE 826 Query: 1121 GGGPGHPGTPGLEQVRTPTSSSG-APPP 1147 G PG G G V P SG A PP Sbjct: 827 RGAPGEKGEGGPPGVAGPPGGSGPAGPP 854 Score = 98.6 bits (244), Expect = 4e-20 Identities = 300/1195 (25%), Positives = 368/1195 (30%), Gaps = 215/1195 (17%) Query: 42 GGPPGPVDPAMSALGEP-PILGMNMEPYGFHARGHSELHAGGLQAQPVHGFFGGQQPH-- 98 G P P P + E P N P S + GGL P G G P Sbjct: 127 GQPGSPGSPGPPGICESCPTGPQNYSPQYDSYDVKSGVAVGGLAGYP--GPAGPPGPPGP 184 Query: 99 ---HGHPGSHHPHQHHPHFGGNFGGPDPGASCLHGGRLLGYGGAAGGLGSQPPFAEGYEH 155 GHPGS P + G G P G G +G G PP A G Sbjct: 185 PGTSGHPGS----PGSPGYQGPPGEP-------------GQAGPSGPPG--PPGAIGPSG 225 Query: 156 MAESQGPESFGPQRPGNLPDFHSSGASSHAVPAPCLPLDQSPNRAASFHGLPSSSGSDSH 215 A G ES P RPG +P P P + P F G+ G D Sbjct: 226 PAGKDG-ESGRPGRPGE-----------RGLPGP--PGIKGPAGIPGFPGMKGHRGFDGR 271 Query: 216 SLEPRRVTNQGAVDSLEYNYPGEAPSGHFDMFSPSDSEGQ-----LPHYAAGRQVPGG-- 268 + E G E PGE +G P + G+ LP A R G Sbjct: 272 NGEKGETGAPGLKG--ENGLPGE--NGAPGPMGPRGAPGERGRPGLPGAAGARGNDGARG 327 Query: 269 --AFPGASAMPRAAGMVGLSKMHAQP-PQQQPQQQQQPQQQQQQHGVFFERFSGARKMP- 324 PG P AG G + P P P Q+ + + +GA+ P Sbjct: 328 SDGQPGPPGPPGTAGFPGSPGAKGEVGPAGSPGSNGAPGQRGEPGP---QGHAGAQGPPG 384 Query: 325 -VGLEPSVGSRHPLMQPPQQAPPPPQQQPPQQPPQQQPPP-PPGLLVRQNSCPPAL---- 378 G+ S G + + P P P + PP PGL R + P Sbjct: 385 PPGINGSPGGKGEM--GPAGIPGAPGLMGARGPPGPAGANGAPGL--RGGAGEPGKNGAK 440 Query: 379 ----PRPQQGEAG---TPSGGLQDGGPMLPSQHAQFEYPIHRLENRSMHPYSEPVFSMQH 431 PR ++GEAG P +DG P + P E R + P Sbjct: 441 GEPGPRGERGEAGIPGVPGAKGEDGKDGSPGEPGANGLPGAAGE-RGAPGFRGPAGPNGI 499 Query: 432 PPPQQAPNQRLQHFDAPPYMNVAKRPRFDFPGSAGVDRCASWNGSMHNGALDNHLSPSAY 491 P + +R A P + R PG G+ GS D P Sbjct: 500 PGEKGPAGERGAPGPAGPRGAAGEPGRDGVPGGPGM---RGMPGSPGGPGSDGKPGP--- 553 Query: 492 PGLPGEFTPPVPDSFPSGPPLQHPAPDHQSLQQQQQQQQQQQQQQQQQQQQQQQQQQQQR 551 PG GE P P PSGP Q P + + ++ Q Sbjct: 554 PGSQGESGRPGPPG-PSGPRGQ---PGVMGFPGPKGNDGAPGKNGERGGPGGPGPQGPPG 609 Query: 552 QNAALMIKQMASRNQQQRLRQPNLAQLGHPGDVGQGG-LVHGGPVGGLAQPNFEREGGST 610 +N G PG G GG GP G GG Sbjct: 610 KNG-------------------ETGPQGPPGPTGPGGDKGDTGPPGPQGLQGLPGTGGPP 650 Query: 611 GA-GRLGTFEQQAPHLAQESAWFSGPHPPPGDLLPRRMGGS-GLPADCGPHDP-----SL 663 G G+ G + A + G PG+ P + G+ GL GP P + Sbjct: 651 GENGKPGEPGPKGDAGAPGAPGGKGDAGAPGERGPPGLAGAPGLRGGAGPPGPEGGKGAA 710 Query: 664 APPPPPGGSGVLF-------RGPLQEPMRM--------PGEGHVPALPSPGLQFG--GSL 706 PP PPG +G RG L P PG VP P G G Sbjct: 711 GPPGPPGAAGTPGLQGMPGERGGLGSPGPKGDKGEPGGPGADGVPGKDGPRGPTGPIGPP 770 Query: 707 GGLGQLQSPGAG--VGLPSAASERRPPPPDFATSALGGQPGFPFGAAGRQSTPHSGPGVN 764 G GQ G G GLP A R P T G GFP GA G+ P G G Sbjct: 771 GPAGQPGDKGEGGAPGLPGIAGPRGSPGERGETGP-PGPAGFP-GAPGQNGEP-GGKGER 827 Query: 765 SPPSAGGGGGSSG----GGGGGGAYPPQPDFQPSQRTSASKLGALSL----GSFNKPSSK 816 P G GG G GG G A PP P +R S GA G P S Sbjct: 828 GAPGEKGEGGPPGVAGPPGGSGPAGPPGPQGVKGERGSPGGPGAAGFPGARGLPGPPGSN 887 Query: 817 DNLFGQSCLAALSTACQNMIASLGAPNLNVTFNKKNPPEGKRKLSQNETDGAAV----AG 872 N G P + + K PP + G + AG Sbjct: 888 GNP--------------------GPPGPSGSPGKDGPPGPAGNTGAPGSPGVSGPKGDAG 927 Query: 873 NPGSDYFPGGTAP-GAPGPGGPSGTSSSGSKASGPPNPPAQGDGTSLSPNYTLESTSGND 931 PG PG P GAPGP G +G + + A GPP P G S P + G Sbjct: 928 QPGEKGSPGAQGPPGAPGPLGIAGITGARGLA-GPPGMP--GPRGSPGP----QGVKGES 980 Query: 932 GKPVSGGGGRGRGRRKRDSGHVSPGTFFDKYSAAPDSGGAPGVSPGQQQASGAAVGGSSA 991 GKP + G RG GT + P G PG S G G+ G Sbjct: 981 GKPGANGLSGERGPPGPQGLPGLAGT-----AGEPGRDGNPG-SDGLPGRDGSPGGKGDR 1034 Query: 992 GETRGAPTPHEKALTSPSWGKGAELLLGDQPDLIGSLDGGAKSDSSSPNVGEFASDEVST 1051 GE P P G GD+ + G + +P G S Sbjct: 1035 GENGSPGAPGAPGHPGPPGPVGPAGKSGDRGE------SGPAGPAGAP--GPAGSRGAPG 1086 Query: 1052 SYANEDEVSSSSDNPQALVKASRS-PLVTGSPKLP-PRG----VGA-------GEHGPKA 1098 + + + A +K R P G+P P P G +G+ G GP Sbjct: 1087 PQGPRGDKGETGERGAAGIKGHRGFPGNPGAPGSPGPAGQQGAIGSPGPAGPRGPVGPSG 1146 Query: 1099 PPPALGLGIMSNSTSTP------DSYGGGGGPGHPGTPGLEQVRTPTSSSGAPPP 1147 PP G P G G PGHPG PG P GAP P Sbjct: 1147 PPGKDGTSGHPGPIGPPGPRGNRGERGSEGSPGHPGQPG------PPGPPGAPGP 1195 Score = 97.1 bits (240), Expect = 1e-19 Identities = 163/603 (27%), Positives = 198/603 (32%), Gaps = 126/603 (20%) Query: 579 GHPGDVGQGGLVHG-GPVGGLAQPNFEREGGSTGAGRLGTFEQQAPHLAQESAWFSGPHP 637 G PG G+ G GP G QP G G AP E GP P Sbjct: 552 GPPGSQGESGRPGPPGPSGPRGQPGVMGFPGPKG-------NDGAPGKNGERGGPGGPGP 604 Query: 638 --PPGDLLPRRMGGSGLPADCGPHDPS--LAPPPPPGGSGVLFRGPLQEPMRMPGEGHVP 693 PPG G G P GP PP P G G+ G PGE P Sbjct: 605 QGPPGK--NGETGPQGPPGPTGPGGDKGDTGPPGPQGLQGLPGTGG------PPGENGKP 656 Query: 694 ALPSPGLQFG--GSLGGLGQLQSPGAG-----VGLPSAASERRPPPPDFATSALGGQPGF 746 P P G G+ GG G +PG G P PP P+ A G P Sbjct: 657 GEPGPKGDAGAPGAPGGKGDAGAPGERGPPGLAGAPGLRGGAGPPGPEGGKGAAG--PPG 714 Query: 747 PFGAAGRQSTPHSGPGVNSPPSAGGGGGSSGGGGGGGAYP-PQPDFQPSQRTSASKLGAL 805 P GAAG PG+ P GG GS G G G P D P + G + Sbjct: 715 PPGAAGT-------PGLQGMPGERGGLGSPGPKGDKGEPGGPGADGVPGKDGPRGPTGPI 767 Query: 806 SL-GSFNKPSSKDNLFGQSCLAALSTACQNMIASLGAPNLNVTFNKKNPPEGKRKLSQNE 864 G +P K G+ GAP L + P G+R Sbjct: 768 GPPGPAGQPGDK----GEG----------------GAPGLPGIAGPRGSP-GERG-ETGP 805 Query: 865 TDGAAVAGNPGSDYFPGGT----APGAPGPGGPSGTSS--SGSKASGPPNPPAQGDGTSL 918 A G PG + PGG APG G GGP G + GS +GPP P QG Sbjct: 806 PGPAGFPGAPGQNGEPGGKGERGAPGEKGEGGPPGVAGPPGGSGPAGPPGP--QG----- 858 Query: 919 SPNYTLESTSGNDGKPVSGGGGRGRGRRKRDSGHVSPGTFFDKYSAAPDSGGAPGVS--P 976 ++ G+ G P + G RG + +PG P G+PG P Sbjct: 859 -----VKGERGSPGGPGAAGFPGARGLPGPPGSNGNPGP--------PGPSGSPGKDGPP 905 Query: 977 GQQQASGAAVGGSSAGETRGAPTPHEKALTSPSWGKGAELLLGDQPDLIGSLDGGAKSDS 1036 G +GA +G A P EK GA LG I + G A+ + Sbjct: 906 GPAGNTGAPGSPGVSGPKGDAGQPGEKGSPGAQGPPGAPGPLG-----IAGITG-ARGLA 959 Query: 1037 SSPNVGEFASDEVSTSYANEDEVSSSSDNPQALVKASRSPLVTGSPKLPPRGVGAGEHGP 1096 P + S PQ + S P G +GE GP Sbjct: 960 GPPGMPG----------------PRGSPGPQGVKGESGKPGANGL---------SGERGP 994 Query: 1097 KAPPPALGLGIMSNSTSTPDSYGGGGGPGHPGTPGLEQVRTPTSSSGAP-------PPDE 1149 P GL + + G G PG G+PG + R S GAP PP Sbjct: 995 PGPQGLPGLAGTAGEPGRDGNPGSDGLPGRDGSPGGKGDRGENGSPGAPGAPGHPGPPGP 1054 Query: 1150 IHP 1152 + P Sbjct: 1055 VGP 1057 Score = 72.4 bits (176), Expect = 3e-12 Identities = 252/1055 (23%), Positives = 321/1055 (30%), Gaps = 192/1055 (18%) Query: 43 GPPGPVDPAMSALGEPPILGMNMEPYGFHARGHSELHAGGLQAQP-----VHGFFG---- 93 G PGP+ P G P G P ARG+ Q P GF G Sbjct: 294 GAPGPMGPR----GAPGERGRPGLPGAAGARGNDGARGSDGQPGPPGPPGTAGFPGSPGA 349 Query: 94 -GQQPHHGHPGSHH-PHQH-HPHFGGNFGGPDPGASCLHGGRLLGYGGAAGGLGSQPPFA 150 G+ G PGS+ P Q P G+ G P G G+ GG G P Sbjct: 350 KGEVGPAGSPGSNGAPGQRGEPGPQGHAGAQGPPGPP-------GINGSPGGKGEMGPAG 402 Query: 151 -EGYEHMAESQGPESFGPQRPGNLPDFHSSGASSHAVPAPCLPLDQSPNRAASFHGLPSS 209 G + ++GP GP P A P + A G+P + Sbjct: 403 IPGAPGLMGARGPP--GPAGANGAPGLRGGAGEPGKNGAKGEPGPRGERGEAGIPGVPGA 460 Query: 210 SGSDSHSLEPRRVTNQGAVDSL-EYNYPG----EAPSGHFDMFSPSDSEGQL----PHYA 260 G D P G + E PG P+G P+ G P A Sbjct: 461 KGEDGKDGSPGEPGANGLPGAAGERGAPGFRGPAGPNGIPGEKGPAGERGAPGPAGPRGA 520 Query: 261 AGRQ----VPGGAFPGASAMPRAAGMVGLSKMHAQPPQQQPQQQQQ----PQQQQQQHGV 312 AG VPGG PG MP + G G S PP Q + + P + Q GV Sbjct: 521 AGEPGRDGVPGG--PGMRGMPGSPGGPG-SDGKPGPPGSQGESGRPGPPGPSGPRGQPGV 577 Query: 313 FFERFSGARKMPVGLEPSVGSRHPLMQPPQQAPPPPQQQPPQQPPQQQPPPPPGLLVRQN 372 F G P G + + G P P P + + PQ PP P G + Sbjct: 578 M--GFPG----PKGNDGAPGKNGERGGPGGPGPQGPPGKNGETGPQG-PPGPTGPGGDKG 630 Query: 373 SCPPALPRPQQGEAGTPSGGLQDGGPMLPSQHAQFEYPIHRLENRSMHPYSEPVFSMQHP 432 P P+ QG GT ++G P P P + + + Sbjct: 631 DTGPPGPQGLQGLPGTGGPPGENGKPGEPGPKGDAGAP------GAPGGKGDAGAPGERG 684 Query: 433 PPQQAPNQRLQHFDAPPYMNVAKRPRFDF--PGSAGVDRCASWNGSMHNGALDNHLSPSA 490 PP A L+ PP K PG+AG G Sbjct: 685 PPGLAGAPGLRGGAGPPGPEGGKGAAGPPGPPGAAGTPGLQGMPGERGGLGSPGPKGDKG 744 Query: 491 YPGLPGEFTPPVPDSFPSGP--PLQHPAPDHQSLQQQQQQQQQQQQQQQQQQQQQQQQQQ 548 PG PG P D P GP P+ P P Q + + Sbjct: 745 EPGGPGADGVPGKDG-PRGPTGPIGPPGP----------------------AGQPGDKGE 781 Query: 549 QQRQNAALMIKQMASRNQQQRLRQPNLAQLGHPGDVGQGGLVHGGPVGGLAQPNFEREGG 608 + S ++ P A G PG GQ G G G P + EGG Sbjct: 782 GGAPGLPGIAGPRGSPGERGETGPPGPA--GFPGAPGQNG--EPGGKGERGAPGEKGEGG 837 Query: 609 STGA-------------GRLGTFEQQAPHLAQESAWFSG----PHPPPGDLLPRRMGGSG 651 G G G ++ +A F G P PP + P G SG Sbjct: 838 PPGVAGPPGGSGPAGPPGPQGVKGERGSPGGPGAAGFPGARGLPGPPGSNGNPGPPGPSG 897 Query: 652 LPADCGPHDPS--LAPPPPPGGSGVLFRGPLQEPMRM--PGEGHVPALPSPGLQFGGSLG 707 P GP P+ P PG SG +G +P PG P P P L G G Sbjct: 898 SPGKDGPPGPAGNTGAPGSPGVSGP--KGDAGQPGEKGSPGAQGPPGAPGP-LGIAGITG 954 Query: 708 GLGQLQSPGA----------GV----GLPSA---ASERRPPPPDFATSALG--------G 742 G PG GV G P A + ER PP P G G Sbjct: 955 ARGLAGPPGMPGPRGSPGPQGVKGESGKPGANGLSGERGPPGPQGLPGLAGTAGEPGRDG 1014 Query: 743 QPGFPFGAAGRQSTP-------------------HSGP-GVNSPPSAGGGGGSSGGGGGG 782 PG G GR +P H GP G P G G SG G Sbjct: 1015 NPGSD-GLPGRDGSPGGKGDRGENGSPGAPGAPGHPGPPGPVGPAGKSGDRGESGPAGPA 1073 Query: 783 GAYPPQ-------PDFQPSQRTSASKLGALSL-------GSFNKPSSKDNLFGQSCLAAL 828 GA P P + + GA + G+ P S Q + + Sbjct: 1074 GAPGPAGSRGAPGPQGPRGDKGETGERGAAGIKGHRGFPGNPGAPGSPGPAGQQGAIGSP 1133 Query: 829 STAC-QNMIASLGAPNLNVTFNKKNP-----PEGKRKLSQNETDGA-AVAGNPGSDYFPG 881 A + + G P + T P P G R + ++G+ G PG PG Sbjct: 1134 GPAGPRGPVGPSGPPGKDGTSGHPGPIGPPGPRGNR--GERGSEGSPGHPGQPGPPGPPG 1191 Query: 882 GTAPGAPGPGGPSGTSSSGSKASGPPNPPAQGDG------TSLSPNYTLESTSGNDGKPV 935 P G G + G KA G P GD + +L+S +G + Sbjct: 1192 APGPCCGGVGAAAIAGIGGEKAGG--FAPYYGDEPMDFKINTDEIMTSLKSVNGQIESLI 1249 Query: 936 SGGGGR-GRGRRKRDSGHVSPGTFFDKYSAAPDSG 969 S G R R RD P +Y P+ G Sbjct: 1250 SPDGSRKNPARNCRDLKFCHPELKSGEYWVDPNQG 1284 Score = 58.2 bits (139), Expect = 5e-08 Identities = 87/348 (25%), Positives = 115/348 (33%), Gaps = 53/348 (15%) Query: 829 STACQNMIAS---LGAPNLNVTFNK------------KNPPEGKRKLSQNETDGA-AVAG 872 S C ++I L PN + F + PP G+ G + G Sbjct: 59 SVLCDDIICDDQELDCPNPEIPFGECCAVCPQPPTAPTRPPNGQGPQGPKGDPGPPGIPG 118 Query: 873 NPGSDYFPGGTAPGAPGPGGPSGTSSSGSKASGPPNPPAQGDGTSLSPNYTLESTSGNDG 932 G PG PG+PG GP G S +GP N Q D + + +G G Sbjct: 119 RNGDPGIPG--QPGSPGSPGPPGICESCP--TGPQNYSPQYDSYDVKSGVAVGGLAGYPG 174 Query: 933 KPVSGGGGRGRGRRKRDSGHV-SPGTFFDKYSAAPDSGGAPGVS--PGQQQASGAAVGGS 989 G G SGH SPG+ Y P G G S PG A G + Sbjct: 175 P----AGPPGPPGPPGTSGHPGSPGS--PGYQGPPGEPGQAGPSGPPGPPGAIGPSGPAG 228 Query: 990 SAGETRGAPTPHEKALTSPSWGKGAELLLGDQPDLIG--SLDG--GAKSDSSSPNVGEFA 1045 GE+ P E+ L P KG + G P + G DG G K ++ +P + Sbjct: 229 KDGESGRPGRPGERGLPGPPGIKGPAGIPGF-PGMKGHRGFDGRNGEKGETGAPGL---- 283 Query: 1046 SDEVSTSYANEDEVSSSSDNPQALVKASRSPLVTGSPKLPPRGVGAGEHGPKA------P 1099 E+ + + P + +P G P LP G G + P Sbjct: 284 --------KGENGLPGENGAPGPMGPRG-APGERGRPGLPGAAGARGNDGARGSDGQPGP 334 Query: 1100 PPALGLGIMSNSTSTPDSYGGGGGPGHPGTPGLEQVRTPTSSSGAPPP 1147 P G S G G PG G PG P +GA P Sbjct: 335 PGPPGTAGFPGSPGAKGEVGPAGSPGSNGAPGQRGEPGPQGHAGAQGP 382 Score = 54.3 bits (129), Expect = 8e-07 Identities = 102/447 (22%), Positives = 141/447 (31%), Gaps = 62/447 (13%) Query: 730 PPPPDFATSALGGQ-PGFPFGAAGRQSTPHSGPGVNSPPSAGGGGGSSGGGGGGGAYPPQ 788 P PP T GQ P P G G P PG N P G GS G G G Sbjct: 89 PQPPTAPTRPPNGQGPQGPKGDPG----PPGIPGRNGDPGIPGQPGSPGSPGPPGICESC 144 Query: 789 P----DFQPSQRTSASKLGAL--SLGSFNKPSSKDNLFGQSCLAALSTACQNMIASLGAP 842 P ++ P + K G L + P+ G + G P Sbjct: 145 PTGPQNYSPQYDSYDVKSGVAVGGLAGYPGPAGPPGPPGPP-------------GTSGHP 191 Query: 843 NLNVTFNKKNPPEGKRKLSQNETDGAAVAGNPGSDYFPGGTAPGAPGPGGPSGTSSSGSK 902 + + PP E A +G PG PGA GP GP+G + Sbjct: 192 GSPGSPGYQGPP--------GEPGQAGPSGPPGP--------PGAIGPSGPAGKDGESGR 235 Query: 903 ASGP-----PNPPAQGDGTSLSPNYTLESTSGNDGKPVSGG--GGRG-RGRRKRDSGHVS 954 P P PP + ++ G DG+ G G G +G + + Sbjct: 236 PGRPGERGLPGPPGIKGPAGIPGFPGMKGHRGFDGRNGEKGETGAPGLKGENGLPGENGA 295 Query: 955 PGTFFDKYSAAPDSGGAPGVSPGQQQASGAAVGGSSAGE--------TRGAP-TPHEKAL 1005 PG + AP G PG+ PG A G S G+ T G P +P K Sbjct: 296 PGPMGPR--GAPGERGRPGL-PGAAGARGNDGARGSDGQPGPPGPPGTAGFPGSPGAKGE 352 Query: 1006 TSPSWGKGAELLLGDQPDLIGSLDGGAKSDSSSPNVGEFASDEVSTSYANEDEVSS--SS 1063 P+ G+ G + + GA+ P + + A + Sbjct: 353 VGPAGSPGSNGAPGQRGEPGPQGHAGAQGPPGPPGINGSPGGKGEMGPAGIPGAPGLMGA 412 Query: 1064 DNPQALVKASRSPLVTGSPKLPPRGVGAGEHGPKAPPPALGLGIMSNSTSTPDSYGGGGG 1123 P A+ +P + G P + GE GP+ G+ + + G G Sbjct: 413 RGPPGPAGANGAPGLRGGAGEPGKNGAKGEPGPRGERGEAGIPGVPGAKGEDGKDGSPGE 472 Query: 1124 PGHPGTPGLEQVRTPTSSSGAPPPDEI 1150 PG G PG R G P+ I Sbjct: 473 PGANGLPGAAGERGAPGFRGPAGPNGI 499 Score = 44.3 bits (103), Expect = 8e-04 Identities = 172/673 (25%), Positives = 211/673 (31%), Gaps = 157/673 (23%) Query: 41 TGGPPGPVDPAMSALGEPPILGMNMEPYGFHARGHS----ELHAGGLQAQPVHGFFGGQQ 96 TGGPPG GEP G P +G + E GL P G GG Sbjct: 646 TGGPPGENGKP----GEPGPKGDAGAPGAPGGKGDAGAPGERGPPGLAGAP--GLRGGAG 699 Query: 97 PHHGHPGSHHPHQHHPHFGGNFGGPD--PGASCLHGGRLLGYGGAAGGLGSQPPFAEGYE 154 P PG P G GP PGA+ G L G G GGLGS P + Sbjct: 700 P----PG--------PEGGKGAAGPPGPPGAAGTPG--LQGMPGERGGLGSPGPKGD--- 742 Query: 155 HMAESQGPESFGPQRPGNLPDFHSSGASSHAVPAPCLPLDQSPNRAASFHGLPSSSGSDS 214 E GP + G PG +G PA P D+ A G+ GS Sbjct: 743 -KGEPGGPGADGV--PGKDGPRGPTGPIGPPGPAG-QPGDKGEGGAPGLPGIAGPRGSPG 798 Query: 215 HSLEPRRVTNQGAVDSLEYNYPGEAPSGHFDMFSPSDSEGQLPHYAAGRQVPGGAFPGAS 274 E G +PG AP + + G+ A G + GG PG + Sbjct: 799 ERGETGPPGPAG--------FPG-APGQN------GEPGGKGERGAPGEKGEGGP-PGVA 842 Query: 275 AMPRAAGMVGLSKMHAQPPQQQPQQQQQPQQQQQQHGVFFERFSGARKMPVGLEPSVGSR 334 P +G G P Q ++ G F GAR +P Sbjct: 843 GPPGGSGPAG-----------PPGPQGVKGERGSPGGPGAAGFPGARGLP---------- 881 Query: 335 HPLMQPPQQAPPPPQQQPPQQPPQQQPPPPPGLLVRQNSCPPALPR---PQQGEAGTPSG 391 PP P P P + PP P G S + P+ Q GE G+P Sbjct: 882 ----GPPGSNGNPGPPGPSGSPGKDGPPGPAGNTGAPGSPGVSGPKGDAGQPGEKGSPGA 937 Query: 392 -------------------GLQDGGPMLPSQHAQFEYPIHRLENRSMHPYSEPVFSMQHP 432 GL G P +P ++ S P + + + P Sbjct: 938 QGPPGAPGPLGIAGITGARGLA-GPPGMPGPRG--SPGPQGVKGESGKPGANGLSGERGP 994 Query: 433 PPQQAPNQRLQHFDAPPYMNVAKRPRFDFPGSAGVDRCASWNGSM-HNGALDNHLSPSAY 491 P Q P A P D G+ G D +GS G + SP A Sbjct: 995 PGPQG---------LPGLAGTAGEPGRD--GNPGSDGLPGRDGSPGGKGDRGENGSPGA- 1042 Query: 492 PGLPGEFTPPVP--------DSFPSGP--PLQHPAPDHQSLQQQQQQQQQQQQQQQQQQQ 541 PG PG PP P D SGP P P P + Q Sbjct: 1043 PGAPGHPGPPGPVGPAGKSGDRGESGPAGPAGAPGP--------------AGSRGAPGPQ 1088 Query: 542 QQQQQQQQQRQNAALMIKQMASRNQQQRLRQPNLAQLGHPGDVGQGGLVHGGPVGGLAQP 601 + + + + A IK R N G PG GQ G + G P G A P Sbjct: 1089 GPRGDKGETGERGAAGIK-------GHRGFPGNPGAPGSPGPAGQQGAI-GSP--GPAGP 1138 Query: 602 NFEREGGSTGAGRLGTFEQQAPHLAQESAWFSGPHPPPGDLLPRRMGGS-GLPADCGPHD 660 G S G+ GT P GP P G+ R GS G P GP Sbjct: 1139 R-GPVGPSGPPGKDGTSGHPGP---------IGPPGPRGNRGERGSEGSPGHPGQPGPPG 1188 Query: 661 PSLAPPPPPGGSG 673 P AP P GG G Sbjct: 1189 PPGAPGPCCGGVG 1201 Score = 42.4 bits (98), Expect = 0.003 Identities = 109/404 (26%), Positives = 125/404 (30%), Gaps = 73/404 (18%) Query: 9 PQVNSRNAGQGERNF-NETGLSMNTHFKAPAFHTGGPPGPVDP-AMSALGEPP----ILG 62 P N G+GER E G GGPPG P S PP + G Sbjct: 815 PGQNGEPGGKGERGAPGEKG-------------EGGPPGVAGPPGGSGPAGPPGPQGVKG 861 Query: 63 MNMEPYGFHARGHSELHAGGLQAQPVHGFFGGQQPHHGHPGSHHPHQHHPHFGGNFGGP- 121 P G A G A GL P G G PG P P GN G P Sbjct: 862 ERGSPGGPGAAGFPG--ARGLPGPPGSNGNPGPPGPSGSPGKDGP----PGPAGNTGAPG 915 Query: 122 DPGASCLHGGRLLGYGGAAGGLGSQ-PPFAEGYEHMAESQGPESFG--PQRPG--NLPDF 176 PG S G G G G G+Q PP A G +A G P PG P Sbjct: 916 SPGVSGPKGDA--GQPGEKGSPGAQGPPGAPGPLGIAGITGARGLAGPPGMPGPRGSPGP 973 Query: 177 HSSGASSHAVPAPCLPLDQSPNRAASFHGLPSSSGSD-------SHSLEPRRVTNQGAVD 229 S A L ++ P GL ++G S L R + G D Sbjct: 974 QGVKGESGKPGANGLSGERGPPGPQGLPGLAGTAGEPGRDGNPGSDGLPGRDGSPGGKGD 1033 Query: 230 SLEYNYPGE-------APSGHFDMFSPSDSEGQ--------LPHYAAGRQVPGGAFP--- 271 E PG P G S G+ P A R PG P Sbjct: 1034 RGENGSPGAPGAPGHPGPPGPVGPAGKSGDRGESGPAGPAGAPGPAGSRGAPGPQGPRGD 1093 Query: 272 -GASAMPRAAGMVGLSKMHAQPPQQQPQQQQQPQQQQQQHGVFFERFSGARKMPVGLEPS 330 G + AAG+ G H P P P QQ + +G R PVG Sbjct: 1094 KGETGERGAAGIKG----HRGFPGN-PGAPGSPGPAGQQGAIGSPGPAGPRG-PVGPSGP 1147 Query: 331 VGSRHPLMQPPQQAPPPPQ--------QQPPQQPPQQQPPPPPG 366 G P PP P+ + P P Q PP PPG Sbjct: 1148 PGKDGTSGHPGPIGPPGPRGNRGERGSEGSPGHPGQPGPPGPPG 1191 Score = 32.0 bits (71), Expect = 4.0 Identities = 24/63 (38%), Positives = 25/63 (39%), Gaps = 10/63 (15%) Query: 1091 AGEHGPKAPPPALGLGIMSNSTSTPDSYGGGGGPGHPGTPGLEQVRTPTSSSGAP-PPDE 1149 AG GP PP G S +P S G G PG PG G SG P PP Sbjct: 170 AGYPGPAGPPGPPGPPGTSGHPGSPGSPGYQGPPGEPGQAG---------PSGPPGPPGA 220 Query: 1150 IHP 1152 I P Sbjct: 221 IGP 223 >gi|15890086 type IV collagen alpha 5 isoform 2 precursor [Homo sapiens] Length = 1691 Score = 105 bits (262), Expect = 3e-22 Identities = 291/1236 (23%), Positives = 375/1236 (30%), Gaps = 285/1236 (23%) Query: 94 GQQPHHGHPGSHHPHQHHPHFGGNFGGPDPGASCLHGGRLLGYGGAAGGLGSQPPFAEGY 153 G++ G PG H P F G G P P G + G G G G PP G+ Sbjct: 45 GEKGERGFPGLEG-HPGLPGFPGPEGPPGPRGQKGDDG-IPGPPGPKGIRG--PPGLPGF 100 Query: 154 EHMAESQG-PESFGPQRPGNLPDFHSSGASSHAVPAPCLPLDQSPNRAASFHGLPSSSGS 212 G P G P +P + + +P P Q P G+ GS Sbjct: 101 PGTPGLPGMPGHDGAPGPQGIPGCNGTKGERGFPGSPGFPGLQGPPGPPGIPGMKGEPGS 160 Query: 213 DSHSLEPRRVTNQGAVDSLEYNYPGEAPSGHFDMFSPSDSEGQLPHYAAGRQVPGGAF-- 270 S P N G YPG P G + P+ G + G P G Sbjct: 161 IIMSSLPGPKGNPG--------YPG--PPGIQGLPGPTGIPGPI-----GPPGPPGLMGP 205 Query: 271 PGASAMPRAAGMVGLSKMHAQPPQQQPQQQQQP----QQQQQQHGVFFERFSGARKMPVG 326 PG +P G +GL+ + + + Q P Q +Q+ + E G + +P Sbjct: 206 PGPPGLPGPKGNMGLNFQGPKGEKGEQGLQGPPGPPGQISEQKRPIDVEFQKGDQGLP-- 263 Query: 327 LEPSVGSRHPLMQPPQQAPPPP----------QQQP------------------------ 352 G R P P + PP P Q +P Sbjct: 264 -----GDRGPPGPPGIRGPPGPPGGEKGEKGEQGEPGKRGKPGKDGENGQPGIPGLPGDP 318 Query: 353 --PQQPPQQQ---------PPPPPGLLVRQNSCPPALPRPQQGEAGTPSGGLQDGGPMLP 401 P +P + PP PPGL++ PRP G G + G P LP Sbjct: 319 GYPGEPGRDGEKGQKGDTGPPGPPGLVI---------PRPGTGITIGEKGNI--GLPGLP 367 Query: 402 SQHAQFEYPIHRLENRSMHPYSEPVFSMQHPPPQQAPNQRLQHFDAPPYMNVAKRPRFDF 461 + + +P ++ P M P P P +R Q D P P Sbjct: 368 GEKGERGFP--GIQGPPGLPGPPGAAVMGPPGPPGFPGERGQKGDEGP-------PGISI 418 Query: 462 PGSAGVDRCASWNGSMHNGALDNHLSPSAYPGLPGEFTPPVPDSFPSGPPLQHPAPDHQS 521 PG G+D P A PGLPG P GP H P + Sbjct: 419 PGPPGLDG-----------------QPGA-PGLPG----------PPGPAGPHIPPSDEI 450 Query: 522 LQQQQQQQQQQQQQQQQQQQQQQQQQQQQRQNAALMIKQMASRNQQQRLRQPNL-AQLGH 580 + + Q +Q + + + Q P LG Sbjct: 451 CEPGPPGPPGSPGDKGLQGEQGVKGDKGDTCFNCIGTGISGPPGQPGLPGLPGPPGSLGF 510 Query: 581 PGDVGQGGLVHG-------GPVGGLAQPNFEREGGSTG-----------AGRLGTFEQQA 622 PG G+ G G G P F G G G LG+ A Sbjct: 511 PGQKGEKGQAGATGPKGLPGIPGAPGAPGFPGSKGEPGDILTFPGMKGDKGELGS--PGA 568 Query: 623 PHL-------AQESA-WFSGPHPPPGDLL-------PRRMGGSGLPADCGPHDP-SLAPP 666 P L Q+ GP PG + P G GLP + GP P PP Sbjct: 569 PGLPGLPGTPGQDGLPGLPGPKGEPGGITFKGERGPPGNPGLPGLPGNIGPMGPPGFGPP 628 Query: 667 PPPGGSGVL----------FRGPLQEP---MRMPGEGHVPALPS----------PGLQFG 703 P G G+ GP +P + PG+ +P P PGL Sbjct: 629 GPVGEKGIQGVAGNPGQPGIPGPKGDPGQTITQPGKPGLPGNPGRDGDVGLPGDPGLPGQ 688 Query: 704 GSLGGL-GQLQSPGA-GVGLPSAASERR----PPPPDFATS----ALGGQPGFPFGAAGR 753 L G+ G PG G+GLP + P PP + L G PG P G G Sbjct: 689 PGLPGIPGSKGEPGIPGIGLPGPPGPKGFPGIPGPPGAPGTPGRIGLEGPPGPP-GFPGP 747 Query: 754 QSTPHSG-PGVNSPPSAGGGGGSSGGGGGGGAYPPQPDFQPSQRTSASKLGALSLGSFNK 812 + P PG PP G G+ G G G +P P P RT L G Sbjct: 748 KGEPGFALPGPPGPPGLPGFKGALGPKGDRG-FPGPPG--PPGRTGLDGLPGPK-GDVG- 802 Query: 813 PSSKDNLFGQSCLAALST----ACQNMIASLGAPNLNVTFNKKNPPEGKRKLSQNETDGA 868 P+ + G L + + +G P L+ +K P G Sbjct: 803 PNGQPGPMGPPGLPGIGVQGPPGPPGIPGPIGQPGLHGIPGEKGDPG---------PPGL 853 Query: 869 AVAGNPGSDYFPGGTAPGAPGPGGPSGTSSSGSKAS--------------GPPNPPAQGD 914 V G PG PG PGAPGP GP G+ KA GPP PP Sbjct: 854 DVPGPPGERGSPG--IPGAPGPIGPPGSPGLPGKAGASGFPGTKGEMGMMGPPGPPGPLG 911 Query: 915 GTSLSPNYTLESTSGNDGKPVSGG-----GGRGRGRRKRDSGHVSPGTFFDK-YSAAPDS 968 S L+ G G+P G G +G G + P K P Sbjct: 912 IPGRSGVPGLKGDDGLQGQPGLPGPTGEKGSKGEPGLPGPPGPMDPNLLGSKGEKGEPGL 971 Query: 969 GGAPGVS-----------PGQQQASGAAVGGSSAGETRGAPTPHEKALTSPSWGKGAELL 1017 G PGVS PGQ SG G P + L P KG Sbjct: 972 PGIPGVSGPKGYQGLPGDPGQPGLSGQPGLPGPPGPKGNPGLPGQPGLIGPPGLKGT--- 1028 Query: 1018 LGDQ-------------PDLIGSLDG-----GAKSDSSSPNVGEFA--------SDEVST 1051 +GD P + G G K D P + + Sbjct: 1029 IGDMGFPGPQGVEGPPGPSGVPGQPGSPGLPGQKGDKGDPGISSIGLPGLPGPKGEPGLP 1088 Query: 1052 SYANEDEVSSSSDNPQALVKASRSPLVTGSPKLPPRGVGAGEHGPKAPPPALGLGIMSNS 1111 Y + S +P L +P G P LP G G PP G+ + Sbjct: 1089 GYPGNPGIKGSVGDP-GLPGLPGTPGAKGQPGLP------GFPGTPGPPGPKGISGPPGN 1141 Query: 1112 TSTPDSYGGGGGPGHPGTPGLEQVRTPTSSSGAPPP 1147 P G GG GHPG PG + G P P Sbjct: 1142 PGLPGEPGPVGGGGHPGQPGPPGEKGKPGQDGIPGP 1177 Score = 98.2 bits (243), Expect = 5e-20 Identities = 237/980 (24%), Positives = 297/980 (30%), Gaps = 190/980 (19%) Query: 271 PGASAMPRAAGMVGLSKMHAQP-PQQQPQQQQQPQQQQQQHGVFFERFSGARKMPVGLEP 329 PGA +P G G + P P+ +P G+ F+ G P GL Sbjct: 566 PGAPGLPGLPGTPGQDGLPGLPGPKGEPG------------GITFKGERGPPGNP-GLPG 612 Query: 330 SVGSRHPLMQPPQQAPPPPQQQP--------PQQPPQQQPPPPPGLLVRQNSCPPALPRP 381 G+ P M PP PP P + P QP P PG + Q P P Sbjct: 613 LPGNIGP-MGPPGFGPPGPVGEKGIQGVAGNPGQPGIPGPKGDPGQTITQPGKPGLPGNP 671 Query: 382 -QQGEAGTPSG-GL--QDGGPMLPSQHAQFEYPIHRLENRSMHPYSEPVFSMQHPPPQQA 437 + G+ G P GL Q G P +P + P L P + + PP Sbjct: 672 GRDGDVGLPGDPGLPGQPGLPGIPGSKGEPGIPGIGLPGP---PGPKGFPGIPGPPGAPG 728 Query: 438 PNQRLQHFDAPP----YMNVAKRPRFDFPGSAGVDRCASWNGSMHNGALDNHLSPSAYPG 493 R+ + PP + P F PG G + G+ L P G Sbjct: 729 TPGRIG-LEGPPGPPGFPGPKGEPGFALPGPPGPPGLPGFKGA---------LGPKGDRG 778 Query: 494 LPGEFTPPVPDSFPSGPPLQHPAPDHQSLQQQQQQQQQQQQQQQQQQQQQQQQQQQQRQN 553 PG PP P L P D Sbjct: 779 FPG---PPGPPGRTGLDGLPGPKGD----------------------------------- 800 Query: 554 AALMIKQMASRNQQQRLRQPNLAQLGHPGDVGQGGLVHGGPVGGLAQPNFEREGGSTGAG 613 + Q + P L +G G G G+ GP+G E G G Sbjct: 801 -------VGPNGQPGPMGPPGLPGIGVQGPPGPPGIP--GPIGQPGLHGIPGEKGDPGPP 851 Query: 614 RLGTFEQQAPHLAQESAWFSGPHPPPGDL-LPRRMGGSGLPADCGPHDPSLAPPPPPGGS 672 L + GP PPG LP + G SG P G + PP PPG Sbjct: 852 GLDVPGPPGERGSPGIPGAPGPIGPPGSPGLPGKAGASGFPGTKGEMG-MMGPPGPPGPL 910 Query: 673 GVLFRGP---------------LQEPMRMPGEGHVPALPSP-GLQFGGSLGGLGQLQSPG 716 G+ R L P G P LP P G LG G+ PG Sbjct: 911 GIPGRSGVPGLKGDDGLQGQPGLPGPTGEKGSKGEPGLPGPPGPMDPNLLGSKGEKGEPG 970 Query: 717 AGVGLPSAASER--RPPPPDFATSALGGQPGFPFGAAGRQSTPH--SGPGVNSPPSAGGG 772 G+P + + + P D L GQPG P G G + P PG+ PP G Sbjct: 971 LP-GIPGVSGPKGYQGLPGDPGQPGLSGQPGLP-GPPGPKGNPGLPGQPGLIGPPGLKGT 1028 Query: 773 GGSSG--------GGGGGGAYPPQPDFQ--PSQRTSASKLGALSLGSFNKPSSKDNLFGQ 822 G G G G P QP P Q+ G S+G P K G+ Sbjct: 1029 IGDMGFPGPQGVEGPPGPSGVPGQPGSPGLPGQKGDKGDPGISSIGLPGLPGPK----GE 1084 Query: 823 SCLAAL--STACQNMIASLGAPNLNVTFNKKNPPEGKRKLSQNETDGA-AVAGNPGSDYF 879 L + + + G P L T K P G ++G PG+ Sbjct: 1085 PGLPGYPGNPGIKGSVGDPGLPGLPGTPGAKGQPGLPGFPGTPGPPGPKGISGPPGNPGL 1144 Query: 880 PG-------GTAPGAPGPGGPSGTSSS-------------GSKASGPPNPPAQGDGTSLS 919 PG G PG PGP G G G G P PP + Sbjct: 1145 PGEPGPVGGGGHPGQPGPPGEKGKPGQDGIPGPAGQKGEPGQPGFGNPGPPGLPGLSGQK 1204 Query: 920 PNYTLESTSGNDGKPVSGG--GGRG-RGRRKRDSGHVSPGTFFDKYSAAPDSGGAPGVS- 975 + L GN G P G G G G + SPG + P G PG Sbjct: 1205 GDGGLPGIPGNPGLPGPKGEPGFHGFPGVQGPPGPPGSPGPALEGPKGNPGPQGPPGRPG 1264 Query: 976 -------PGQQQASGAAVGGSSAGETRGAPTPHEKALTSPSWGKGAELLLGD--QPDLIG 1026 PG + G G GE P L +G L G+ +P L Sbjct: 1265 PTGFQGLPGPEGPPGLPGNGGIKGEKGNPGQPGLPGLPGLKGDQGPPGLQGNPGRPGL-- 1322 Query: 1027 SLDGGAKSDSSSPNVGEFASDE----VSTSYANEDEVSS-SSDNPQALVKASRSPLV--- 1078 G K D P V F + V S E E P L S ++ Sbjct: 1323 ---NGMKGDPGLPGVPGFPGMKGPSGVPGSAGPEGEPGLIGPPGPPGLPGPSGQSIIIKG 1379 Query: 1079 -TGSPKLP----------PRGVGAGEHGPKAPPPALGLGIMSNSTSTPDSYGGGGGPGHP 1127 G P +P P+G G GP PP G + G G PG P Sbjct: 1380 DAGPPGIPGQPGLKGLPGPQGP-QGLPGPTGPPGDPGRNGLPGFDGAGGRKGDPGLPGQP 1438 Query: 1128 GTPGLEQVRTPTSSSGAPPP 1147 GT GL+ P G P P Sbjct: 1439 GTRGLDGPPGPDGLQGPPGP 1458 Score = 87.8 bits (216), Expect = 6e-17 Identities = 300/1234 (24%), Positives = 376/1234 (30%), Gaps = 230/1234 (18%) Query: 43 GPPGPVD-PAMSALGEPPILGMNMEPYGFHARGHSELHAGGLQAQP----VHGFFGGQQP 97 GPPGP P M GEP + M+ P G+ G+Q P + G G P Sbjct: 144 GPPGPPGIPGMK--GEPGSIIMSSLPGPKGNPGYPG--PPGIQGLPGPTGIPGPIGPPGP 199 Query: 98 HH--GHPGSHHPHQHHPHFGGNFGGPDPGASCLHGGRLLGYGGAAGGLGSQP-----PFA 150 G PG + G NF GP G G L G G G + Q F Sbjct: 200 PGLMGPPGPPGLPGPKGNMGLNFQGPK-GEKGEQG--LQGPPGPPGQISEQKRPIDVEFQ 256 Query: 151 EGYEHMAESQGPESF-GPQRPGNLPDFHSSGASSHAVPAPC-LPLDQSPNRAASFHGLPS 208 +G + + +GP G + P P P P N GLP Sbjct: 257 KGDQGLPGDRGPPGPPGIRGPPGPPGGEKGEKGEQGEPGKRGKPGKDGENGQPGIPGLPG 316 Query: 209 SSGSDSHSLEPRRVTNQGAVDSLEYNYPGEAPSGHFDMFSPSDSEGQLPHYAAGRQVPG- 267 G EP R +G P G + P G +PG Sbjct: 317 DPGYPG---EPGRDGEKGQKGDT-------GPPGPPGLVIPRPGTGITIGEKGNIGLPGL 366 Query: 268 ------GAFPGASAMPRAAGMVGLSKMHAQPPQQQPQQQQQPQQQQQQHGVFFERFSGAR 321 FPG P G G + M P P ++ Q + + G+ G Sbjct: 367 PGEKGERGFPGIQGPPGLPGPPGAAVMGPPGPPGFPGERGQ-KGDEGPPGISIPGPPGLD 425 Query: 322 KMP--VGLEPSVGSRHPLMQPPQQAPPPPQQQPPQQPPQQQ------------------- 360 P GL G P + P + P PP P + Sbjct: 426 GQPGAPGLPGPPGPAGPHIPPSDEICEPGPPGPPGSPGDKGLQGEQGVKGDKGDTCFNCI 485 Query: 361 ------PPPPPGLLVRQNSCPPALPRP--------QQGEAGTPSGGLQDGGPMLPSQHAQ 406 PP PGL P LP P Q+GE G G P +P Sbjct: 486 GTGISGPPGQPGL--------PGLPGPPGSLGFPGQKGEKGQAGATGPKGLPGIPGAPGA 537 Query: 407 FEYPIHRLENRSMHPYSEPVFSMQHPPPQQAPNQRLQHFDAPPYMNVAKRPRFD----FP 462 +P + E + + P + L AP + P D P Sbjct: 538 PGFPGSKGEPGDILTF----------PGMKGDKGELGSPGAPGLPGLPGTPGQDGLPGLP 587 Query: 463 GSAGVDRCASWNGSMHNGALDNHLSPSAYPGLPGEFTPPVPDSFPSGPPLQHPAPDHQSL 522 G G ++ G G N PGLPG P P F GPP Q + Sbjct: 588 GPKGEPGGITFKGE--RGPPGN----PGLPGLPGNIGPMGPPGF--GPPGPVGEKGIQGV 639 Query: 523 QQQQQQQQQQQQQQQQQQQQQQQQQQQQRQNAALMIKQMASRNQQQRLRQPNLAQL-GHP 581 Q + Q Q + N + QP L + G Sbjct: 640 AGNPGQPGIPGPKGDPGQTITQPGKPGLPGNPG-RDGDVGLPGDPGLPGQPGLPGIPGSK 698 Query: 582 GDVGQGGLVHGGPVGGLAQPNFEREGGSTGA-GRLGTFEQQAPHLAQESAWFSGPHPPPG 640 G+ G G+ GP G P G+ G GR+G P F GP PG Sbjct: 699 GEPGIPGIGLPGPPGPKGFPGIPGPPGAPGTPGRIGLEGPPGP------PGFPGPKGEPG 752 Query: 641 DLLPRRMGGSGLPADCGPHDPS-----LAPPPPPGGSGVL-FRGPLQE--PMRMPGEGHV 692 LP G GLP G P PP PPG +G+ GP + P PG Sbjct: 753 FALPGPPGPPGLPGFKGALGPKGDRGFPGPPGPPGRTGLDGLPGPKGDVGPNGQPGPMGP 812 Query: 693 PALPSPGLQFGGSLGGL-GQLQSPGAGVGLPSAASERRPPPPDF-ATSALGGQPGFPFGA 750 P LP G+Q G+ G + PG G+P + PP D G PG P GA Sbjct: 813 PGLPGIGVQGPPGPPGIPGPIGQPGLH-GIPGEKGDPGPPGLDVPGPPGERGSPGIP-GA 870 Query: 751 AGRQSTPHSGPGVNSPPSAGGGGGSSGGGGGGGAYPPQPDFQPSQRTSASKLGALSLGSF 810 G P S PG+ A G G+ G G G PP P P + G L Sbjct: 871 PGPIGPPGS-PGLPGKAGASGFPGTKGEMGMMG--PPGP---PGPLGIPGRSGVPGL--- 921 Query: 811 NKPSSKDNLFGQSCLAALSTACQNMIASLGAPNLNVTFNKKNPPEGKRKLSQNETDGAAV 870 D L GQ L + S G P L P + N Sbjct: 922 ---KGDDGLQGQPGLPGPT----GEKGSKGEPGL---------PGPPGPMDPNLLGSKGE 965 Query: 871 AGNPGSDYFPGGTAP----GAPGPGGPSGTSSSGSKASGPP----NPPAQGDGTSLSPNY 922 G PG PG + P G PG G G S GPP NP G + P Sbjct: 966 KGEPGLPGIPGVSGPKGYQGLPGDPGQPGLSGQPG-LPGPPGPKGNPGLPGQPGLIGPP- 1023 Query: 923 TLESTSGNDGKPVSGG--------------GGRGRGRRKRDSGHVSPGTFFDKYSAAPDS 968 L+ T G+ G P G G G +K D G PG P Sbjct: 1024 GLKGTIGDMGFPGPQGVEGPPGPSGVPGQPGSPGLPGQKGDKG--DPGISSIGLPGLPGP 1081 Query: 969 GGAPGVS--PGQQQASGAAVGGSSAGETRGAP----------------TPHEKALTSPSW 1010 G PG+ PG G+ VG G P P K ++ P Sbjct: 1082 KGEPGLPGYPGNPGIKGS-VGDPGLPGLPGTPGAKGQPGLPGFPGTPGPPGPKGISGPPG 1140 Query: 1011 GKGAELLLGDQPDLIGSLDGGAKSDSSSPNV-GEFASDEVSTSYANEDEVSS---SSDNP 1066 G L +P +G GG P G+ D + + E + P Sbjct: 1141 NPG----LPGEPGPVGG--GGHPGQPGPPGEKGKPGQDGIPGPAGQKGEPGQPGFGNPGP 1194 Query: 1067 QALVKASRS------PLVTGSPKLP-PRGVGA-----GEHGPKAPPPALGLGIMSNSTST 1114 L S P + G+P LP P+G G GP PP + G Sbjct: 1195 PGLPGLSGQKGDGGLPGIPGNPGLPGPKGEPGFHGFPGVQGPPGPPGSPG---------- 1244 Query: 1115 PDSYGGGGGPGHPGTPGLEQVRTPTSSSGAPPPD 1148 P G G PG G PG PT G P P+ Sbjct: 1245 PALEGPKGNPGPQGPPGRPG---PTGFQGLPGPE 1275 Score = 76.6 bits (187), Expect = 1e-13 Identities = 154/597 (25%), Positives = 197/597 (32%), Gaps = 122/597 (20%) Query: 579 GHPGDVGQGGLVHGGPVGGLAQPNFEREGGSTGAGRLGTFEQQAPHLAQESAWFSGPHPP 638 G PG G GL GP G P + E GS L + + P PP Sbjct: 132 GFPGSPGFPGLQ--GPPGPPGIPGMKGEPGSIIMSSLPGPKGNPGY----------PGPP 179 Query: 639 PGDLLPRRMGGSGLPADCGPHDPS--LAPPPPPG------GSGVLFRGPLQEPMRMPGEG 690 LP G +G+P GP P + PP PPG G+ F+GP E GE Sbjct: 180 GIQGLP---GPTGIPGPIGPPGPPGLMGPPGPPGLPGPKGNMGLNFQGPKGEK----GEQ 232 Query: 691 HVPALPSPGLQFGGSLGGLGQLQSPGAGVGLPSAASERRPPPPDFATSALGGQPGFPFGA 750 + P P Q + ++ GLP +R PP P + G PG P G Sbjct: 233 GLQGPPGPPGQISEQKRPI-DVEFQKGDQGLPG---DRGPPGPP----GIRGPPGPPGGE 284 Query: 751 AGRQSTPHSGPGVNSPPSAGGGGGSSGGGG--GGGAYPPQP--DFQPSQRTSASKLGALS 806 G + PG P G G G G G YP +P D + Q+ G Sbjct: 285 KGEKGE-QGEPGKRGKPGKDGENGQPGIPGLPGDPGYPGEPGRDGEKGQKGDTGPPGPPG 343 Query: 807 LGSFNKPSSKDNLFGQSCLAALSTACQNMIASLGAPNLNVTFNKKNPPEGKRKLSQNETD 866 L +P + + G+ ++G P L ++ P + Sbjct: 344 L-VIPRPGTGITI-GEK-------------GNIGLPGLPGEKGERGFPGIQGPPGLPGPP 388 Query: 867 GAAVAGNPGSDYFPGGTAPGAPGPGGPSGTSSSGSK-------ASGPPNPPAQGDGTSLS 919 GAAV G PG FPG G G GP G S G A G P PP G + Sbjct: 389 GAAVMGPPGPPGFPGER--GQKGDEGPPGISIPGPPGLDGQPGAPGLPGPPGPA-GPHIP 445 Query: 920 PNYTLESTSGNDGKPVSGG--GGRGRGRRKRDSGHVSPGTFFDKYSAAPDSGGAPGVSPG 977 P+ + G G P S G G +G K D G S P G PG+ PG Sbjct: 446 PSDEI-CEPGPPGPPGSPGDKGLQGEQGVKGDKGDTCFNCIGTGISGPPGQPGLPGL-PG 503 Query: 978 QQQASGAAVGGSSAGETRGAPTPHEKALTSPSWGKGAELLLGD--QPDLIGSLDG--GAK 1033 + G G+ GA P K L GA G +P I + G G K Sbjct: 504 PPGSLGFPGQKGEKGQA-GATGP--KGLPGIPGAPGAPGFPGSKGEPGDILTFPGMKGDK 560 Query: 1034 SDSSSPNVGEFASDEVSTSYANEDEVSSSSDNPQALVKASRSPLVTGSPKLPPRGVGAGE 1093 + SP +P + G P P + G Sbjct: 561 GELGSPG----------------------------------APGLPGLPGTPGQDGLPGL 586 Query: 1094 HGPKAPPPALGLGIMSNSTSTPDSYGGGGGPGHPGTPGLEQVRTPTSSSGAPPPDEI 1150 GPK P + G G PG+PG PGL P G PP + Sbjct: 587 PGPKGEPGGITFK------------GERGPPGNPGLPGLPGNIGPMGPPGFGPPGPV 631 Score = 50.8 bits (120), Expect = 8e-06 Identities = 90/364 (24%), Positives = 122/364 (33%), Gaps = 69/364 (18%) Query: 863 NETDGAAVAGNPGSDYFPGGTA----PGAPGPGGPSGTSSSGSKAS----GPPNP----- 909 ++ D + + G G FPG PG PGP GP G G K GPP P Sbjct: 36 SKCDCSGIKGEKGERGFPGLEGHPGLPGFPGPEGPPGPR--GQKGDDGIPGPPGPKGIRG 93 Query: 910 PAQGDGTSLSPNYTLESTSGNDGKPVSGGGGRGRGRRKRDSGHVSPGTFFDKYSAAPDSG 969 P G +P L G+DG P G G + SPG F P Sbjct: 94 PPGLPGFPGTPG--LPGMPGHDGAPGPQGIPGCNGTKGERGFPGSPG--FPGLQGPP--- 146 Query: 970 GAPGVSPGQQQASGAAVGGSSAGETRGAP----------TPHEKALTSPSWGKGAELLLG 1019 G PG+ PG + G+ + S G +G P P + P G L+G Sbjct: 147 GPPGI-PGMKGEPGSIIMSSLPGP-KGNPGYPGPPGIQGLPGPTGIPGPIGPPGPPGLMG 204 Query: 1020 DQ--PDLIGSLDG------GAKSDSSSPNV-------GEFASDE--VSTSYANEDEVSSS 1062 P L G G K + + G+ + + + + D+ Sbjct: 205 PPGPPGLPGPKGNMGLNFQGPKGEKGEQGLQGPPGPPGQISEQKRPIDVEFQKGDQGLPG 264 Query: 1063 SDNPQALVKASRSPLVTGSPKLPPRGVGAGEHGPKAPPPALGLGIMSNSTSTPDSYGGGG 1122 P P + G P P G GE G + P G P G G Sbjct: 265 DRGPPG------PPGIRGPPG--PPGGEKGEKGEQGEPGKRGKPGKDGENGQPGIPGLPG 316 Query: 1123 GPGHPGTPGLEQVRTPTSSSGAPPPDEIHPLEILQAQIQLQRQQFSISEDQPLGLKG--G 1180 PG+PG PG + + +G P P + I +I E +GL G G Sbjct: 317 DPGYPGEPGRDGEKGQKGDTGPPGPPGL--------VIPRPGTGITIGEKGNIGLPGLPG 368 Query: 1181 KKGE 1184 +KGE Sbjct: 369 EKGE 372 Score = 46.2 bits (108), Expect = 2e-04 Identities = 162/657 (24%), Positives = 198/657 (30%), Gaps = 167/657 (25%) Query: 43 GPPGPVDPAM----SALGEPPILGMNMEPYGFHARGHSELHAGGLQAQPVHGFFGGQQPH 98 GPPGP+DP + GEP + G+ P +G+ GL P GQ Sbjct: 950 GPPGPMDPNLLGSKGEKGEPGLPGI---PGVSGPKGYQ-----GLPGDP------GQPGL 995 Query: 99 HGHPGSHHPHQHHPHFGGNFGGP-DPGASCLHGGRLLGYGGAAGGLGSQP-PFAEGYEHM 156 G PG P P GN G P PG L+G G G +G P +G E Sbjct: 996 SGQPGLPGP----PGPKGNPGLPGQPG--------LIGPPGLKGTIGDMGFPGPQGVEGP 1043 Query: 157 AESQGP--ESFGPQRPGNLPDFHSSGASSHAVPAPCLPLDQSPNRAASFHGLPSSSGSDS 214 G + P PG D G SS +P LP + + G P GS Sbjct: 1044 PGPSGVPGQPGSPGLPGQKGDKGDPGISSIGLPG--LPGPKGEPGLPGYPGNPGIKGSVG 1101 Query: 215 HSLEPRRVTNQGAVDSLEY-NYPGE-APSGHFDMFSPSDSEGQL--PHYAAGRQVPGGAF 270 P GA +PG P G + P + G P G PG Sbjct: 1102 DPGLPGLPGTPGAKGQPGLPGFPGTPGPPGPKGISGPPGNPGLPGEPGPVGGGGHPGQPG 1161 Query: 271 P-GASAMPRAAGMVGLSKMHAQPPQQ---QPQQQQQPQQQQQQHGVFFERFSGARKMPVG 326 P G P G+ G + +P Q P P Q+ G +P Sbjct: 1162 PPGEKGKPGQDGIPGPAGQKGEPGQPGFGNPGPPGLPGLSGQKGDGGLPGIPGNPGLPGP 1221 Query: 327 L-EPSVGSRHPLMQPPQQ--APPPPQQQPPQQPPQQQPPPPPGLLVRQN----SCPPALP 379 EP + PP +P P + P P Q PP PG Q PP LP Sbjct: 1222 KGEPGFHGFPGVQGPPGPPGSPGPALEGPKGNPGPQGPPGRPGPTGFQGLPGPEGPPGLP 1281 Query: 380 RPQ--QGEAGTPSGGLQDGGPMLPSQHAQFEYPIHRLENRSMHPYSEPVFSMQHPPPQQA 437 +GE G P Q G P LP Q PP Q Sbjct: 1282 GNGGIKGEKGNPG---QPGLPGLPGLKGD-----------------------QGPPGLQG 1315 Query: 438 PNQRLQHFDAPPYMNVAKRPRFDFPGSAGVDRCASWNGSMHNGALDNHLSPSAYPGLPGE 497 R P +N K G G+ + G + P PGL G Sbjct: 1316 NPGR-------PGLNGMK-------GDPGLPGVPGFPGMKGPSGVPGSAGPEGEPGLIG- 1360 Query: 498 FTPPVPDSFPSGPPLQHPAPDHQSLQQQQQQQQQQQQQQQQQQQQQQQQQQQQRQNAALM 557 P GPP P P QS+ + Q Sbjct: 1361 ---------PPGPP-GLPGPSGQSIIIKGDAGPPGIPGQPG------------------- 1391 Query: 558 IKQMASRNQQQRLRQPNLAQLGHPGDVGQGGLVHGGPVGGLAQPNFEREGGSTGAGRLGT 617 +K + Q L P G PGD G+ GL P F+ GG G Sbjct: 1392 LKGLPGPQGPQGLPGPT----GPPGDPGRNGL-----------PGFDGAGGRKG------ 1430 Query: 618 FEQQAPHLAQESAWFSGPHPPPGDLLPRRMGGSGLPADCGPHDPSLAPPPPPGGSGV 674 PG LP + G GL GP D PP PPG S V Sbjct: 1431 --------------------DPG--LPGQPGTRGLDGPPGP-DGLQGPPGPPGTSSV 1464 >gi|4502955 type IV collagen alpha 5 isoform 1 precursor [Homo sapiens] Length = 1685 Score = 105 bits (262), Expect = 3e-22 Identities = 291/1236 (23%), Positives = 375/1236 (30%), Gaps = 285/1236 (23%) Query: 94 GQQPHHGHPGSHHPHQHHPHFGGNFGGPDPGASCLHGGRLLGYGGAAGGLGSQPPFAEGY 153 G++ G PG H P F G G P P G + G G G G PP G+ Sbjct: 45 GEKGERGFPGLEG-HPGLPGFPGPEGPPGPRGQKGDDG-IPGPPGPKGIRG--PPGLPGF 100 Query: 154 EHMAESQG-PESFGPQRPGNLPDFHSSGASSHAVPAPCLPLDQSPNRAASFHGLPSSSGS 212 G P G P +P + + +P P Q P G+ GS Sbjct: 101 PGTPGLPGMPGHDGAPGPQGIPGCNGTKGERGFPGSPGFPGLQGPPGPPGIPGMKGEPGS 160 Query: 213 DSHSLEPRRVTNQGAVDSLEYNYPGEAPSGHFDMFSPSDSEGQLPHYAAGRQVPGGAF-- 270 S P N G YPG P G + P+ G + G P G Sbjct: 161 IIMSSLPGPKGNPG--------YPG--PPGIQGLPGPTGIPGPI-----GPPGPPGLMGP 205 Query: 271 PGASAMPRAAGMVGLSKMHAQPPQQQPQQQQQP----QQQQQQHGVFFERFSGARKMPVG 326 PG +P G +GL+ + + + Q P Q +Q+ + E G + +P Sbjct: 206 PGPPGLPGPKGNMGLNFQGPKGEKGEQGLQGPPGPPGQISEQKRPIDVEFQKGDQGLP-- 263 Query: 327 LEPSVGSRHPLMQPPQQAPPPP----------QQQP------------------------ 352 G R P P + PP P Q +P Sbjct: 264 -----GDRGPPGPPGIRGPPGPPGGEKGEKGEQGEPGKRGKPGKDGENGQPGIPGLPGDP 318 Query: 353 --PQQPPQQQ---------PPPPPGLLVRQNSCPPALPRPQQGEAGTPSGGLQDGGPMLP 401 P +P + PP PPGL++ PRP G G + G P LP Sbjct: 319 GYPGEPGRDGEKGQKGDTGPPGPPGLVI---------PRPGTGITIGEKGNI--GLPGLP 367 Query: 402 SQHAQFEYPIHRLENRSMHPYSEPVFSMQHPPPQQAPNQRLQHFDAPPYMNVAKRPRFDF 461 + + +P ++ P M P P P +R Q D P P Sbjct: 368 GEKGERGFP--GIQGPPGLPGPPGAAVMGPPGPPGFPGERGQKGDEGP-------PGISI 418 Query: 462 PGSAGVDRCASWNGSMHNGALDNHLSPSAYPGLPGEFTPPVPDSFPSGPPLQHPAPDHQS 521 PG G+D P A PGLPG P GP H P + Sbjct: 419 PGPPGLDG-----------------QPGA-PGLPG----------PPGPAGPHIPPSDEI 450 Query: 522 LQQQQQQQQQQQQQQQQQQQQQQQQQQQQRQNAALMIKQMASRNQQQRLRQPNL-AQLGH 580 + + Q +Q + + + Q P LG Sbjct: 451 CEPGPPGPPGSPGDKGLQGEQGVKGDKGDTCFNCIGTGISGPPGQPGLPGLPGPPGSLGF 510 Query: 581 PGDVGQGGLVHG-------GPVGGLAQPNFEREGGSTG-----------AGRLGTFEQQA 622 PG G+ G G G P F G G G LG+ A Sbjct: 511 PGQKGEKGQAGATGPKGLPGIPGAPGAPGFPGSKGEPGDILTFPGMKGDKGELGS--PGA 568 Query: 623 PHL-------AQESA-WFSGPHPPPGDLL-------PRRMGGSGLPADCGPHDP-SLAPP 666 P L Q+ GP PG + P G GLP + GP P PP Sbjct: 569 PGLPGLPGTPGQDGLPGLPGPKGEPGGITFKGERGPPGNPGLPGLPGNIGPMGPPGFGPP 628 Query: 667 PPPGGSGVL----------FRGPLQEP---MRMPGEGHVPALPS----------PGLQFG 703 P G G+ GP +P + PG+ +P P PGL Sbjct: 629 GPVGEKGIQGVAGNPGQPGIPGPKGDPGQTITQPGKPGLPGNPGRDGDVGLPGDPGLPGQ 688 Query: 704 GSLGGL-GQLQSPGA-GVGLPSAASERR----PPPPDFATS----ALGGQPGFPFGAAGR 753 L G+ G PG G+GLP + P PP + L G PG P G G Sbjct: 689 PGLPGIPGSKGEPGIPGIGLPGPPGPKGFPGIPGPPGAPGTPGRIGLEGPPGPP-GFPGP 747 Query: 754 QSTPHSG-PGVNSPPSAGGGGGSSGGGGGGGAYPPQPDFQPSQRTSASKLGALSLGSFNK 812 + P PG PP G G+ G G G +P P P RT L G Sbjct: 748 KGEPGFALPGPPGPPGLPGFKGALGPKGDRG-FPGPPG--PPGRTGLDGLPGPK-GDVG- 802 Query: 813 PSSKDNLFGQSCLAALST----ACQNMIASLGAPNLNVTFNKKNPPEGKRKLSQNETDGA 868 P+ + G L + + +G P L+ +K P G Sbjct: 803 PNGQPGPMGPPGLPGIGVQGPPGPPGIPGPIGQPGLHGIPGEKGDPG---------PPGL 853 Query: 869 AVAGNPGSDYFPGGTAPGAPGPGGPSGTSSSGSKAS--------------GPPNPPAQGD 914 V G PG PG PGAPGP GP G+ KA GPP PP Sbjct: 854 DVPGPPGERGSPG--IPGAPGPIGPPGSPGLPGKAGASGFPGTKGEMGMMGPPGPPGPLG 911 Query: 915 GTSLSPNYTLESTSGNDGKPVSGG-----GGRGRGRRKRDSGHVSPGTFFDK-YSAAPDS 968 S L+ G G+P G G +G G + P K P Sbjct: 912 IPGRSGVPGLKGDDGLQGQPGLPGPTGEKGSKGEPGLPGPPGPMDPNLLGSKGEKGEPGL 971 Query: 969 GGAPGVS-----------PGQQQASGAAVGGSSAGETRGAPTPHEKALTSPSWGKGAELL 1017 G PGVS PGQ SG G P + L P KG Sbjct: 972 PGIPGVSGPKGYQGLPGDPGQPGLSGQPGLPGPPGPKGNPGLPGQPGLIGPPGLKGT--- 1028 Query: 1018 LGDQ-------------PDLIGSLDG-----GAKSDSSSPNVGEFA--------SDEVST 1051 +GD P + G G K D P + + Sbjct: 1029 IGDMGFPGPQGVEGPPGPSGVPGQPGSPGLPGQKGDKGDPGISSIGLPGLPGPKGEPGLP 1088 Query: 1052 SYANEDEVSSSSDNPQALVKASRSPLVTGSPKLPPRGVGAGEHGPKAPPPALGLGIMSNS 1111 Y + S +P L +P G P LP G G PP G+ + Sbjct: 1089 GYPGNPGIKGSVGDP-GLPGLPGTPGAKGQPGLP------GFPGTPGPPGPKGISGPPGN 1141 Query: 1112 TSTPDSYGGGGGPGHPGTPGLEQVRTPTSSSGAPPP 1147 P G GG GHPG PG + G P P Sbjct: 1142 PGLPGEPGPVGGGGHPGQPGPPGEKGKPGQDGIPGP 1177 Score = 100 bits (249), Expect = 9e-21 Identities = 237/974 (24%), Positives = 297/974 (30%), Gaps = 184/974 (18%) Query: 271 PGASAMPRAAGMVGLSKMHAQP-PQQQPQQQQQPQQQQQQHGVFFERFSGARKMPVGLEP 329 PGA +P G G + P P+ +P G+ F+ G P GL Sbjct: 566 PGAPGLPGLPGTPGQDGLPGLPGPKGEPG------------GITFKGERGPPGNP-GLPG 612 Query: 330 SVGSRHPLMQPPQQAPPPPQQQP--------PQQPPQQQPPPPPGLLVRQNSCPPALPRP 381 G+ P M PP PP P + P QP P PG + Q P P Sbjct: 613 LPGNIGP-MGPPGFGPPGPVGEKGIQGVAGNPGQPGIPGPKGDPGQTITQPGKPGLPGNP 671 Query: 382 -QQGEAGTPSG-GL--QDGGPMLPSQHAQFEYPIHRLENRSMHPYSEPVFSMQHPPPQQA 437 + G+ G P GL Q G P +P + P L P + + PP Sbjct: 672 GRDGDVGLPGDPGLPGQPGLPGIPGSKGEPGIPGIGLPGP---PGPKGFPGIPGPPGAPG 728 Query: 438 PNQRLQHFDAPP----YMNVAKRPRFDFPGSAGVDRCASWNGSMHNGALDNHLSPSAYPG 493 R+ + PP + P F PG G + G+ L P G Sbjct: 729 TPGRIG-LEGPPGPPGFPGPKGEPGFALPGPPGPPGLPGFKGA---------LGPKGDRG 778 Query: 494 LPGEFTPPVPDSFPSGPPLQHPAPDHQSLQQQQQQQQQQQQQQQQQQQQQQQQQQQQRQN 553 PG PP P L P D Sbjct: 779 FPG---PPGPPGRTGLDGLPGPKGD----------------------------------- 800 Query: 554 AALMIKQMASRNQQQRLRQPNLAQLGHPGDVGQGGLVHGGPVGGLAQPNFEREGGSTGAG 613 + Q + P L +G G G G+ GP+G E G G Sbjct: 801 -------VGPNGQPGPMGPPGLPGIGVQGPPGPPGIP--GPIGQPGLHGIPGEKGDPGPP 851 Query: 614 RLGTFEQQAPHLAQESAWFSGPHPPPGDL-LPRRMGGSGLPADCGPHDPSLAPPPPPGGS 672 L + GP PPG LP + G SG P G + PP PPG Sbjct: 852 GLDVPGPPGERGSPGIPGAPGPIGPPGSPGLPGKAGASGFPGTKGEMG-MMGPPGPPGPL 910 Query: 673 GVLFRGP---------------LQEPMRMPGEGHVPALPSP-GLQFGGSLGGLGQLQSPG 716 G+ R L P G P LP P G LG G+ PG Sbjct: 911 GIPGRSGVPGLKGDDGLQGQPGLPGPTGEKGSKGEPGLPGPPGPMDPNLLGSKGEKGEPG 970 Query: 717 AGVGLPSAASER--RPPPPDFATSALGGQPGFPFGAAGRQSTPH--SGPGVNSPPSAGGG 772 G+P + + + P D L GQPG P G G + P PG+ PP G Sbjct: 971 LP-GIPGVSGPKGYQGLPGDPGQPGLSGQPGLP-GPPGPKGNPGLPGQPGLIGPPGLKGT 1028 Query: 773 GGSSG--------GGGGGGAYPPQPDFQ--PSQRTSASKLGALSLGSFNKPSSKDNLFGQ 822 G G G G P QP P Q+ G S+G P K G+ Sbjct: 1029 IGDMGFPGPQGVEGPPGPSGVPGQPGSPGLPGQKGDKGDPGISSIGLPGLPGPK----GE 1084 Query: 823 SCLAAL--STACQNMIASLGAPNLNVTFNKKNPPEGKRKLSQNETDGA-AVAGNPGSDYF 879 L + + + G P L T K P G ++G PG+ Sbjct: 1085 PGLPGYPGNPGIKGSVGDPGLPGLPGTPGAKGQPGLPGFPGTPGPPGPKGISGPPGNPGL 1144 Query: 880 PG-------GTAPGAPGPGGPSGTSSS-------------GSKASGPPNPPAQGDGTSLS 919 PG G PG PGP G G G G P PP + Sbjct: 1145 PGEPGPVGGGGHPGQPGPPGEKGKPGQDGIPGPAGQKGEPGQPGFGNPGPPGLPGLSGQK 1204 Query: 920 PNYTLESTSGNDGKPVSGG--GGRG-RGRRKRDSGHVSPGTFFDKYSAAPDSGGAPGVS- 975 + L GN G P G G G G + SPG + P G PG Sbjct: 1205 GDGGLPGIPGNPGLPGPKGEPGFHGFPGVQGPPGPPGSPGPALEGPKGNPGPQGPPGRPG 1264 Query: 976 -PGQQQASGAAVGGSSAGETRGAPTPHEKALTSPSWGKGAELLLGD--QPDLIGSLDGGA 1032 PG + G G GE P L +G L G+ +P L G Sbjct: 1265 LPGPEGPPGLPGNGGIKGEKGNPGQPGLPGLPGLKGDQGPPGLQGNPGRPGL-----NGM 1319 Query: 1033 KSDSSSPNVGEFASDE----VSTSYANEDEVSS-SSDNPQALVKASRSPLV----TGSPK 1083 K D P V F + V S E E P L S ++ G P Sbjct: 1320 KGDPGLPGVPGFPGMKGPSGVPGSAGPEGEPGLIGPPGPPGLPGPSGQSIIIKGDAGPPG 1379 Query: 1084 LP----------PRGVGAGEHGPKAPPPALGLGIMSNSTSTPDSYGGGGGPGHPGTPGLE 1133 +P P+G G GP PP G + G G PG PGT GL+ Sbjct: 1380 IPGQPGLKGLPGPQGP-QGLPGPTGPPGDPGRNGLPGFDGAGGRKGDPGLPGQPGTRGLD 1438 Query: 1134 QVRTPTSSSGAPPP 1147 P G P P Sbjct: 1439 GPPGPDGLQGPPGP 1452 Score = 76.6 bits (187), Expect = 1e-13 Identities = 154/597 (25%), Positives = 197/597 (32%), Gaps = 122/597 (20%) Query: 579 GHPGDVGQGGLVHGGPVGGLAQPNFEREGGSTGAGRLGTFEQQAPHLAQESAWFSGPHPP 638 G PG G GL GP G P + E GS L + + P PP Sbjct: 132 GFPGSPGFPGLQ--GPPGPPGIPGMKGEPGSIIMSSLPGPKGNPGY----------PGPP 179 Query: 639 PGDLLPRRMGGSGLPADCGPHDPS--LAPPPPPG------GSGVLFRGPLQEPMRMPGEG 690 LP G +G+P GP P + PP PPG G+ F+GP E GE Sbjct: 180 GIQGLP---GPTGIPGPIGPPGPPGLMGPPGPPGLPGPKGNMGLNFQGPKGEK----GEQ 232 Query: 691 HVPALPSPGLQFGGSLGGLGQLQSPGAGVGLPSAASERRPPPPDFATSALGGQPGFPFGA 750 + P P Q + ++ GLP +R PP P + G PG P G Sbjct: 233 GLQGPPGPPGQISEQKRPI-DVEFQKGDQGLPG---DRGPPGPP----GIRGPPGPPGGE 284 Query: 751 AGRQSTPHSGPGVNSPPSAGGGGGSSGGGG--GGGAYPPQP--DFQPSQRTSASKLGALS 806 G + PG P G G G G G YP +P D + Q+ G Sbjct: 285 KGEKGE-QGEPGKRGKPGKDGENGQPGIPGLPGDPGYPGEPGRDGEKGQKGDTGPPGPPG 343 Query: 807 LGSFNKPSSKDNLFGQSCLAALSTACQNMIASLGAPNLNVTFNKKNPPEGKRKLSQNETD 866 L +P + + G+ ++G P L ++ P + Sbjct: 344 L-VIPRPGTGITI-GEK-------------GNIGLPGLPGEKGERGFPGIQGPPGLPGPP 388 Query: 867 GAAVAGNPGSDYFPGGTAPGAPGPGGPSGTSSSGSK-------ASGPPNPPAQGDGTSLS 919 GAAV G PG FPG G G GP G S G A G P PP G + Sbjct: 389 GAAVMGPPGPPGFPGER--GQKGDEGPPGISIPGPPGLDGQPGAPGLPGPPGPA-GPHIP 445 Query: 920 PNYTLESTSGNDGKPVSGG--GGRGRGRRKRDSGHVSPGTFFDKYSAAPDSGGAPGVSPG 977 P+ + G G P S G G +G K D G S P G PG+ PG Sbjct: 446 PSDEI-CEPGPPGPPGSPGDKGLQGEQGVKGDKGDTCFNCIGTGISGPPGQPGLPGL-PG 503 Query: 978 QQQASGAAVGGSSAGETRGAPTPHEKALTSPSWGKGAELLLGD--QPDLIGSLDG--GAK 1033 + G G+ GA P K L GA G +P I + G G K Sbjct: 504 PPGSLGFPGQKGEKGQA-GATGP--KGLPGIPGAPGAPGFPGSKGEPGDILTFPGMKGDK 560 Query: 1034 SDSSSPNVGEFASDEVSTSYANEDEVSSSSDNPQALVKASRSPLVTGSPKLPPRGVGAGE 1093 + SP +P + G P P + G Sbjct: 561 GELGSPG----------------------------------APGLPGLPGTPGQDGLPGL 586 Query: 1094 HGPKAPPPALGLGIMSNSTSTPDSYGGGGGPGHPGTPGLEQVRTPTSSSGAPPPDEI 1150 GPK P + G G PG+PG PGL P G PP + Sbjct: 587 PGPKGEPGGITFK------------GERGPPGNPGLPGLPGNIGPMGPPGFGPPGPV 631 Score = 50.8 bits (120), Expect = 8e-06 Identities = 90/364 (24%), Positives = 122/364 (33%), Gaps = 69/364 (18%) Query: 863 NETDGAAVAGNPGSDYFPGGTA----PGAPGPGGPSGTSSSGSKAS----GPPNP----- 909 ++ D + + G G FPG PG PGP GP G G K GPP P Sbjct: 36 SKCDCSGIKGEKGERGFPGLEGHPGLPGFPGPEGPPGPR--GQKGDDGIPGPPGPKGIRG 93 Query: 910 PAQGDGTSLSPNYTLESTSGNDGKPVSGGGGRGRGRRKRDSGHVSPGTFFDKYSAAPDSG 969 P G +P L G+DG P G G + SPG F P Sbjct: 94 PPGLPGFPGTPG--LPGMPGHDGAPGPQGIPGCNGTKGERGFPGSPG--FPGLQGPP--- 146 Query: 970 GAPGVSPGQQQASGAAVGGSSAGETRGAP----------TPHEKALTSPSWGKGAELLLG 1019 G PG+ PG + G+ + S G +G P P + P G L+G Sbjct: 147 GPPGI-PGMKGEPGSIIMSSLPGP-KGNPGYPGPPGIQGLPGPTGIPGPIGPPGPPGLMG 204 Query: 1020 DQ--PDLIGSLDG------GAKSDSSSPNV-------GEFASDE--VSTSYANEDEVSSS 1062 P L G G K + + G+ + + + + D+ Sbjct: 205 PPGPPGLPGPKGNMGLNFQGPKGEKGEQGLQGPPGPPGQISEQKRPIDVEFQKGDQGLPG 264 Query: 1063 SDNPQALVKASRSPLVTGSPKLPPRGVGAGEHGPKAPPPALGLGIMSNSTSTPDSYGGGG 1122 P P + G P P G GE G + P G P G G Sbjct: 265 DRGPPG------PPGIRGPPG--PPGGEKGEKGEQGEPGKRGKPGKDGENGQPGIPGLPG 316 Query: 1123 GPGHPGTPGLEQVRTPTSSSGAPPPDEIHPLEILQAQIQLQRQQFSISEDQPLGLKG--G 1180 PG+PG PG + + +G P P + I +I E +GL G G Sbjct: 317 DPGYPGEPGRDGEKGQKGDTGPPGPPGL--------VIPRPGTGITIGEKGNIGLPGLPG 368 Query: 1181 KKGE 1184 +KGE Sbjct: 369 EKGE 372 Score = 49.3 bits (116), Expect = 2e-05 Identities = 162/653 (24%), Positives = 199/653 (30%), Gaps = 165/653 (25%) Query: 43 GPPGPVDPAM----SALGEPPILGMNMEPYGFHARGHSELHAGGLQAQPVHGFFGGQQPH 98 GPPGP+DP + GEP + G+ P +G+ GL P GQ Sbjct: 950 GPPGPMDPNLLGSKGEKGEPGLPGI---PGVSGPKGYQ-----GLPGDP------GQPGL 995 Query: 99 HGHPGSHHPHQHHPHFGGNFGGP-DPGASCLHGGRLLGYGGAAGGLGSQP-PFAEGYEHM 156 G PG P P GN G P PG L+G G G +G P +G E Sbjct: 996 SGQPGLPGP----PGPKGNPGLPGQPG--------LIGPPGLKGTIGDMGFPGPQGVEGP 1043 Query: 157 AESQGP--ESFGPQRPGNLPDFHSSGASSHAVPAPCLPLDQSPNRAASFHGLPSSSGSDS 214 G + P PG D G SS +P LP + + G P GS Sbjct: 1044 PGPSGVPGQPGSPGLPGQKGDKGDPGISSIGLPG--LPGPKGEPGLPGYPGNPGIKGSVG 1101 Query: 215 HSLEPRRVTNQGAVDSLEY-NYPGE-APSGHFDMFSPSDSEGQL--PHYAAGRQVPGGAF 270 P GA +PG P G + P + G P G PG Sbjct: 1102 DPGLPGLPGTPGAKGQPGLPGFPGTPGPPGPKGISGPPGNPGLPGEPGPVGGGGHPGQPG 1161 Query: 271 P-GASAMPRAAGMVGLSKMHAQPPQQ---QPQQQQQPQQQQQQHGVFFERFSGARKMPVG 326 P G P G+ G + +P Q P P Q+ G +P Sbjct: 1162 PPGEKGKPGQDGIPGPAGQKGEPGQPGFGNPGPPGLPGLSGQKGDGGLPGIPGNPGLPGP 1221 Query: 327 L-EPSVGSRHPLMQPPQQ--APPPPQQQPPQQPPQQQPPPPPGLLVRQNSCPPALPRPQ- 382 EP + PP +P P + P P Q PP PGL + PP LP Sbjct: 1222 KGEPGFHGFPGVQGPPGPPGSPGPALEGPKGNPGPQGPPGRPGLPGPEG--PPGLPGNGG 1279 Query: 383 -QGEAGTPSGGLQDGGPMLPSQHAQFEYPIHRLENRSMHPYSEPVFSMQHPPPQQAPNQR 441 +GE G P Q G P LP Q PP Q R Sbjct: 1280 IKGEKGNPG---QPGLPGLPGLKGD-----------------------QGPPGLQGNPGR 1313 Query: 442 LQHFDAPPYMNVAKRPRFDFPGSAGVDRCASWNGSMHNGALDNHLSPSAYPGLPGEFTPP 501 P +N K G G+ + G + P PGL G Sbjct: 1314 -------PGLNGMK-------GDPGLPGVPGFPGMKGPSGVPGSAGPEGEPGLIG----- 1354 Query: 502 VPDSFPSGPPLQHPAPDHQSLQQQQQQQQQQQQQQQQQQQQQQQQQQQQRQNAALMIKQM 561 P GPP P P QS+ + Q +K + Sbjct: 1355 -----PPGPP-GLPGPSGQSIIIKGDAGPPGIPGQPG-------------------LKGL 1389 Query: 562 ASRNQQQRLRQPNLAQLGHPGDVGQGGLVHGGPVGGLAQPNFEREGGSTGAGRLGTFEQQ 621 Q L P G PGD G+ GL P F+ GG G Sbjct: 1390 PGPQGPQGLPGPT----GPPGDPGRNGL-----------PGFDGAGGRKG---------- 1424 Query: 622 APHLAQESAWFSGPHPPPGDLLPRRMGGSGLPADCGPHDPSLAPPPPPGGSGV 674 PG LP + G GL GP D PP PPG S V Sbjct: 1425 ----------------DPG--LPGQPGTRGLDGPPGP-DGLQGPPGPPGTSSV 1458 Score = 47.0 bits (110), Expect = 1e-04 Identities = 115/472 (24%), Positives = 145/472 (30%), Gaps = 97/472 (20%) Query: 43 GPPGPVDPAMSALGEPPILGMNMEPYGFHARGHSELHAGGLQAQPVHGFFGGQQPHHGHP 102 GPPGP P + G + G+ + GLQ QP G++ G P Sbjct: 902 GPPGPPGP-LGIPGRSGVPGLKGDD--------------GLQGQPGLPGPTGEKGSKGEP 946 Query: 103 G-SHHPHQHHPHFGGNFGGPD----PGASCLHGGRLLGYGGAAGGLGSQPPFAEGYEHMA 157 G P P+ G+ G PG + G + GY G G G P G + Sbjct: 947 GLPGPPGPMDPNLLGSKGEKGEPGLPGIPGVSGPK--GYQGLPGDPGQ--PGLSGQPGLP 1002 Query: 158 ESQGPESFGPQRPGNLPDFHSSGASSHAVPAPCLPLDQSPNRAASFHGLPSSSGSDSHSL 217 GP+ P PG P + P Q G+P GS Sbjct: 1003 GPPGPKG-NPGLPGQ-PGLIGPPGLKGTIGDMGFPGPQGVEGPPGPSGVPGQPGSPGL-- 1058 Query: 218 EPRRVTNQGAVDSLEYNYPG-EAPSGHFDMFSPSDSEGQLPHYAAGRQVPGGA----FPG 272 P + ++G PG P G E LP Y + G PG Sbjct: 1059 -PGQKGDKGDPGISSIGLPGLPGPKG----------EPGLPGYPGNPGIKGSVGDPGLPG 1107 Query: 273 ASAMPRAAGMVGLSKMHAQPPQQQPQQQQQPQQQQQQHGVFFERFSGARKMPVGLEPSVG 332 P A G GL P P+ P G +P P G Sbjct: 1108 LPGTPGAKGQPGLPGFPGTPGPPGPKGISGPP--------------GNPGLPGEPGPVGG 1153 Query: 333 SRHPLMQ-PPQQAPPPPQQQPPQQPPQQQPPPPPGLLVRQNSCPPALP--RPQQGEAGTP 389 HP PP + P Q P Q+ P PG N PP LP Q+G+ G P Sbjct: 1154 GGHPGQPGPPGEKGKPGQDGIPGPAGQKGEPGQPGF---GNPGPPGLPGLSGQKGDGGLP 1210 Query: 390 SGGLQDGGPMLPSQHAQFEYPIHRLENRSMHPYSEPVF----SMQHPP-PQQAPNQRLQH 444 G P LP P EP F +Q PP P +P L+ Sbjct: 1211 G---IPGNPGLPG------------------PKGEPGFHGFPGVQGPPGPPGSPGPALE- 1248 Query: 445 FDAPPYMNVAKRPRFDFPGSAGVDRCASWNGSMHNGALDNHLSPSAYPGLPG 496 P + P PG G+ G NG + PGLPG Sbjct: 1249 --GPKGNPGPQGP----PGRPGLPGPEGPPGLPGNGGIKGEKGNPGQPGLPG 1294 >gi|15890088 type IV collagen alpha 5 isoform 3 precursor [Homo sapiens] Length = 1688 Score = 105 bits (262), Expect = 3e-22 Identities = 291/1236 (23%), Positives = 375/1236 (30%), Gaps = 285/1236 (23%) Query: 94 GQQPHHGHPGSHHPHQHHPHFGGNFGGPDPGASCLHGGRLLGYGGAAGGLGSQPPFAEGY 153 G++ G PG H P F G G P P G + G G G G PP G+ Sbjct: 45 GEKGERGFPGLEG-HPGLPGFPGPEGPPGPRGQKGDDG-IPGPPGPKGIRG--PPGLPGF 100 Query: 154 EHMAESQG-PESFGPQRPGNLPDFHSSGASSHAVPAPCLPLDQSPNRAASFHGLPSSSGS 212 G P G P +P + + +P P Q P G+ GS Sbjct: 101 PGTPGLPGMPGHDGAPGPQGIPGCNGTKGERGFPGSPGFPGLQGPPGPPGIPGMKGEPGS 160 Query: 213 DSHSLEPRRVTNQGAVDSLEYNYPGEAPSGHFDMFSPSDSEGQLPHYAAGRQVPGGAF-- 270 S P N G YPG P G + P+ G + G P G Sbjct: 161 IIMSSLPGPKGNPG--------YPG--PPGIQGLPGPTGIPGPI-----GPPGPPGLMGP 205 Query: 271 PGASAMPRAAGMVGLSKMHAQPPQQQPQQQQQP----QQQQQQHGVFFERFSGARKMPVG 326 PG +P G +GL+ + + + Q P Q +Q+ + E G + +P Sbjct: 206 PGPPGLPGPKGNMGLNFQGPKGEKGEQGLQGPPGPPGQISEQKRPIDVEFQKGDQGLP-- 263 Query: 327 LEPSVGSRHPLMQPPQQAPPPP----------QQQP------------------------ 352 G R P P + PP P Q +P Sbjct: 264 -----GDRGPPGPPGIRGPPGPPGGEKGEKGEQGEPGKRGKPGKDGENGQPGIPGLPGDP 318 Query: 353 --PQQPPQQQ---------PPPPPGLLVRQNSCPPALPRPQQGEAGTPSGGLQDGGPMLP 401 P +P + PP PPGL++ PRP G G + G P LP Sbjct: 319 GYPGEPGRDGEKGQKGDTGPPGPPGLVI---------PRPGTGITIGEKGNI--GLPGLP 367 Query: 402 SQHAQFEYPIHRLENRSMHPYSEPVFSMQHPPPQQAPNQRLQHFDAPPYMNVAKRPRFDF 461 + + +P ++ P M P P P +R Q D P P Sbjct: 368 GEKGERGFP--GIQGPPGLPGPPGAAVMGPPGPPGFPGERGQKGDEGP-------PGISI 418 Query: 462 PGSAGVDRCASWNGSMHNGALDNHLSPSAYPGLPGEFTPPVPDSFPSGPPLQHPAPDHQS 521 PG G+D P A PGLPG P GP H P + Sbjct: 419 PGPPGLDG-----------------QPGA-PGLPG----------PPGPAGPHIPPSDEI 450 Query: 522 LQQQQQQQQQQQQQQQQQQQQQQQQQQQQRQNAALMIKQMASRNQQQRLRQPNL-AQLGH 580 + + Q +Q + + + Q P LG Sbjct: 451 CEPGPPGPPGSPGDKGLQGEQGVKGDKGDTCFNCIGTGISGPPGQPGLPGLPGPPGSLGF 510 Query: 581 PGDVGQGGLVHG-------GPVGGLAQPNFEREGGSTG-----------AGRLGTFEQQA 622 PG G+ G G G P F G G G LG+ A Sbjct: 511 PGQKGEKGQAGATGPKGLPGIPGAPGAPGFPGSKGEPGDILTFPGMKGDKGELGS--PGA 568 Query: 623 PHL-------AQESA-WFSGPHPPPGDLL-------PRRMGGSGLPADCGPHDP-SLAPP 666 P L Q+ GP PG + P G GLP + GP P PP Sbjct: 569 PGLPGLPGTPGQDGLPGLPGPKGEPGGITFKGERGPPGNPGLPGLPGNIGPMGPPGFGPP 628 Query: 667 PPPGGSGVL----------FRGPLQEP---MRMPGEGHVPALPS----------PGLQFG 703 P G G+ GP +P + PG+ +P P PGL Sbjct: 629 GPVGEKGIQGVAGNPGQPGIPGPKGDPGQTITQPGKPGLPGNPGRDGDVGLPGDPGLPGQ 688 Query: 704 GSLGGL-GQLQSPGA-GVGLPSAASERR----PPPPDFATS----ALGGQPGFPFGAAGR 753 L G+ G PG G+GLP + P PP + L G PG P G G Sbjct: 689 PGLPGIPGSKGEPGIPGIGLPGPPGPKGFPGIPGPPGAPGTPGRIGLEGPPGPP-GFPGP 747 Query: 754 QSTPHSG-PGVNSPPSAGGGGGSSGGGGGGGAYPPQPDFQPSQRTSASKLGALSLGSFNK 812 + P PG PP G G+ G G G +P P P RT L G Sbjct: 748 KGEPGFALPGPPGPPGLPGFKGALGPKGDRG-FPGPPG--PPGRTGLDGLPGPK-GDVG- 802 Query: 813 PSSKDNLFGQSCLAALST----ACQNMIASLGAPNLNVTFNKKNPPEGKRKLSQNETDGA 868 P+ + G L + + +G P L+ +K P G Sbjct: 803 PNGQPGPMGPPGLPGIGVQGPPGPPGIPGPIGQPGLHGIPGEKGDPG---------PPGL 853 Query: 869 AVAGNPGSDYFPGGTAPGAPGPGGPSGTSSSGSKAS--------------GPPNPPAQGD 914 V G PG PG PGAPGP GP G+ KA GPP PP Sbjct: 854 DVPGPPGERGSPG--IPGAPGPIGPPGSPGLPGKAGASGFPGTKGEMGMMGPPGPPGPLG 911 Query: 915 GTSLSPNYTLESTSGNDGKPVSGG-----GGRGRGRRKRDSGHVSPGTFFDK-YSAAPDS 968 S L+ G G+P G G +G G + P K P Sbjct: 912 IPGRSGVPGLKGDDGLQGQPGLPGPTGEKGSKGEPGLPGPPGPMDPNLLGSKGEKGEPGL 971 Query: 969 GGAPGVS-----------PGQQQASGAAVGGSSAGETRGAPTPHEKALTSPSWGKGAELL 1017 G PGVS PGQ SG G P + L P KG Sbjct: 972 PGIPGVSGPKGYQGLPGDPGQPGLSGQPGLPGPPGPKGNPGLPGQPGLIGPPGLKGT--- 1028 Query: 1018 LGDQ-------------PDLIGSLDG-----GAKSDSSSPNVGEFA--------SDEVST 1051 +GD P + G G K D P + + Sbjct: 1029 IGDMGFPGPQGVEGPPGPSGVPGQPGSPGLPGQKGDKGDPGISSIGLPGLPGPKGEPGLP 1088 Query: 1052 SYANEDEVSSSSDNPQALVKASRSPLVTGSPKLPPRGVGAGEHGPKAPPPALGLGIMSNS 1111 Y + S +P L +P G P LP G G PP G+ + Sbjct: 1089 GYPGNPGIKGSVGDP-GLPGLPGTPGAKGQPGLP------GFPGTPGPPGPKGISGPPGN 1141 Query: 1112 TSTPDSYGGGGGPGHPGTPGLEQVRTPTSSSGAPPP 1147 P G GG GHPG PG + G P P Sbjct: 1142 PGLPGEPGPVGGGGHPGQPGPPGEKGKPGQDGIPGP 1177 Score = 99.4 bits (246), Expect = 2e-20 Identities = 237/977 (24%), Positives = 297/977 (30%), Gaps = 187/977 (19%) Query: 271 PGASAMPRAAGMVGLSKMHAQP-PQQQPQQQQQPQQQQQQHGVFFERFSGARKMPVGLEP 329 PGA +P G G + P P+ +P G+ F+ G P GL Sbjct: 566 PGAPGLPGLPGTPGQDGLPGLPGPKGEPG------------GITFKGERGPPGNP-GLPG 612 Query: 330 SVGSRHPLMQPPQQAPPPPQQQP--------PQQPPQQQPPPPPGLLVRQNSCPPALPRP 381 G+ P M PP PP P + P QP P PG + Q P P Sbjct: 613 LPGNIGP-MGPPGFGPPGPVGEKGIQGVAGNPGQPGIPGPKGDPGQTITQPGKPGLPGNP 671 Query: 382 -QQGEAGTPSG-GL--QDGGPMLPSQHAQFEYPIHRLENRSMHPYSEPVFSMQHPPPQQA 437 + G+ G P GL Q G P +P + P L P + + PP Sbjct: 672 GRDGDVGLPGDPGLPGQPGLPGIPGSKGEPGIPGIGLPGP---PGPKGFPGIPGPPGAPG 728 Query: 438 PNQRLQHFDAPP----YMNVAKRPRFDFPGSAGVDRCASWNGSMHNGALDNHLSPSAYPG 493 R+ + PP + P F PG G + G+ L P G Sbjct: 729 TPGRIG-LEGPPGPPGFPGPKGEPGFALPGPPGPPGLPGFKGA---------LGPKGDRG 778 Query: 494 LPGEFTPPVPDSFPSGPPLQHPAPDHQSLQQQQQQQQQQQQQQQQQQQQQQQQQQQQRQN 553 PG PP P L P D Sbjct: 779 FPG---PPGPPGRTGLDGLPGPKGD----------------------------------- 800 Query: 554 AALMIKQMASRNQQQRLRQPNLAQLGHPGDVGQGGLVHGGPVGGLAQPNFEREGGSTGAG 613 + Q + P L +G G G G+ GP+G E G G Sbjct: 801 -------VGPNGQPGPMGPPGLPGIGVQGPPGPPGIP--GPIGQPGLHGIPGEKGDPGPP 851 Query: 614 RLGTFEQQAPHLAQESAWFSGPHPPPGDL-LPRRMGGSGLPADCGPHDPSLAPPPPPGGS 672 L + GP PPG LP + G SG P G + PP PPG Sbjct: 852 GLDVPGPPGERGSPGIPGAPGPIGPPGSPGLPGKAGASGFPGTKGEMG-MMGPPGPPGPL 910 Query: 673 GVLFRGP---------------LQEPMRMPGEGHVPALPSP-GLQFGGSLGGLGQLQSPG 716 G+ R L P G P LP P G LG G+ PG Sbjct: 911 GIPGRSGVPGLKGDDGLQGQPGLPGPTGEKGSKGEPGLPGPPGPMDPNLLGSKGEKGEPG 970 Query: 717 AGVGLPSAASER--RPPPPDFATSALGGQPGFPFGAAGRQSTPH--SGPGVNSPPSAGGG 772 G+P + + + P D L GQPG P G G + P PG+ PP G Sbjct: 971 LP-GIPGVSGPKGYQGLPGDPGQPGLSGQPGLP-GPPGPKGNPGLPGQPGLIGPPGLKGT 1028 Query: 773 GGSSG--------GGGGGGAYPPQPDFQ--PSQRTSASKLGALSLGSFNKPSSKDNLFGQ 822 G G G G P QP P Q+ G S+G P K G+ Sbjct: 1029 IGDMGFPGPQGVEGPPGPSGVPGQPGSPGLPGQKGDKGDPGISSIGLPGLPGPK----GE 1084 Query: 823 SCLAAL--STACQNMIASLGAPNLNVTFNKKNPPEGKRKLSQNETDGA-AVAGNPGSDYF 879 L + + + G P L T K P G ++G PG+ Sbjct: 1085 PGLPGYPGNPGIKGSVGDPGLPGLPGTPGAKGQPGLPGFPGTPGPPGPKGISGPPGNPGL 1144 Query: 880 PG-------GTAPGAPGPGGPSGTSSS-------------GSKASGPPNPPAQGDGTSLS 919 PG G PG PGP G G G G P PP + Sbjct: 1145 PGEPGPVGGGGHPGQPGPPGEKGKPGQDGIPGPAGQKGEPGQPGFGNPGPPGLPGLSGQK 1204 Query: 920 PNYTLESTSGNDGKPVSGG--GGRG-RGRRKRDSGHVSPGTFFDKYSAAPDSGGAPGVS- 975 + L GN G P G G G G + SPG + P G PG Sbjct: 1205 GDGGLPGIPGNPGLPGPKGEPGFHGFPGVQGPPGPPGSPGPALEGPKGNPGPQGPPGRPG 1264 Query: 976 ----PGQQQASGAAVGGSSAGETRGAPTPHEKALTSPSWGKGAELLLGD--QPDLIGSLD 1029 PG + G G GE P L +G L G+ +P L Sbjct: 1265 FQGLPGPEGPPGLPGNGGIKGEKGNPGQPGLPGLPGLKGDQGPPGLQGNPGRPGL----- 1319 Query: 1030 GGAKSDSSSPNVGEFASDE----VSTSYANEDEVSS-SSDNPQALVKASRSPLV----TG 1080 G K D P V F + V S E E P L S ++ G Sbjct: 1320 NGMKGDPGLPGVPGFPGMKGPSGVPGSAGPEGEPGLIGPPGPPGLPGPSGQSIIIKGDAG 1379 Query: 1081 SPKLP----------PRGVGAGEHGPKAPPPALGLGIMSNSTSTPDSYGGGGGPGHPGTP 1130 P +P P+G G GP PP G + G G PG PGT Sbjct: 1380 PPGIPGQPGLKGLPGPQGP-QGLPGPTGPPGDPGRNGLPGFDGAGGRKGDPGLPGQPGTR 1438 Query: 1131 GLEQVRTPTSSSGAPPP 1147 GL+ P G P P Sbjct: 1439 GLDGPPGPDGLQGPPGP 1455 Score = 76.6 bits (187), Expect = 1e-13 Identities = 154/597 (25%), Positives = 197/597 (32%), Gaps = 122/597 (20%) Query: 579 GHPGDVGQGGLVHGGPVGGLAQPNFEREGGSTGAGRLGTFEQQAPHLAQESAWFSGPHPP 638 G PG G GL GP G P + E GS L + + P PP Sbjct: 132 GFPGSPGFPGLQ--GPPGPPGIPGMKGEPGSIIMSSLPGPKGNPGY----------PGPP 179 Query: 639 PGDLLPRRMGGSGLPADCGPHDPS--LAPPPPPG------GSGVLFRGPLQEPMRMPGEG 690 LP G +G+P GP P + PP PPG G+ F+GP E GE Sbjct: 180 GIQGLP---GPTGIPGPIGPPGPPGLMGPPGPPGLPGPKGNMGLNFQGPKGEK----GEQ 232 Query: 691 HVPALPSPGLQFGGSLGGLGQLQSPGAGVGLPSAASERRPPPPDFATSALGGQPGFPFGA 750 + P P Q + ++ GLP +R PP P + G PG P G Sbjct: 233 GLQGPPGPPGQISEQKRPI-DVEFQKGDQGLPG---DRGPPGPP----GIRGPPGPPGGE 284 Query: 751 AGRQSTPHSGPGVNSPPSAGGGGGSSGGGG--GGGAYPPQP--DFQPSQRTSASKLGALS 806 G + PG P G G G G G YP +P D + Q+ G Sbjct: 285 KGEKGE-QGEPGKRGKPGKDGENGQPGIPGLPGDPGYPGEPGRDGEKGQKGDTGPPGPPG 343 Query: 807 LGSFNKPSSKDNLFGQSCLAALSTACQNMIASLGAPNLNVTFNKKNPPEGKRKLSQNETD 866 L +P + + G+ ++G P L ++ P + Sbjct: 344 L-VIPRPGTGITI-GEK-------------GNIGLPGLPGEKGERGFPGIQGPPGLPGPP 388 Query: 867 GAAVAGNPGSDYFPGGTAPGAPGPGGPSGTSSSGSK-------ASGPPNPPAQGDGTSLS 919 GAAV G PG FPG G G GP G S G A G P PP G + Sbjct: 389 GAAVMGPPGPPGFPGER--GQKGDEGPPGISIPGPPGLDGQPGAPGLPGPPGPA-GPHIP 445 Query: 920 PNYTLESTSGNDGKPVSGG--GGRGRGRRKRDSGHVSPGTFFDKYSAAPDSGGAPGVSPG 977 P+ + G G P S G G +G K D G S P G PG+ PG Sbjct: 446 PSDEI-CEPGPPGPPGSPGDKGLQGEQGVKGDKGDTCFNCIGTGISGPPGQPGLPGL-PG 503 Query: 978 QQQASGAAVGGSSAGETRGAPTPHEKALTSPSWGKGAELLLGD--QPDLIGSLDG--GAK 1033 + G G+ GA P K L GA G +P I + G G K Sbjct: 504 PPGSLGFPGQKGEKGQA-GATGP--KGLPGIPGAPGAPGFPGSKGEPGDILTFPGMKGDK 560 Query: 1034 SDSSSPNVGEFASDEVSTSYANEDEVSSSSDNPQALVKASRSPLVTGSPKLPPRGVGAGE 1093 + SP +P + G P P + G Sbjct: 561 GELGSPG----------------------------------APGLPGLPGTPGQDGLPGL 586 Query: 1094 HGPKAPPPALGLGIMSNSTSTPDSYGGGGGPGHPGTPGLEQVRTPTSSSGAPPPDEI 1150 GPK P + G G PG+PG PGL P G PP + Sbjct: 587 PGPKGEPGGITFK------------GERGPPGNPGLPGLPGNIGPMGPPGFGPPGPV 631 Score = 50.8 bits (120), Expect = 8e-06 Identities = 90/364 (24%), Positives = 122/364 (33%), Gaps = 69/364 (18%) Query: 863 NETDGAAVAGNPGSDYFPGGTA----PGAPGPGGPSGTSSSGSKAS----GPPNP----- 909 ++ D + + G G FPG PG PGP GP G G K GPP P Sbjct: 36 SKCDCSGIKGEKGERGFPGLEGHPGLPGFPGPEGPPGPR--GQKGDDGIPGPPGPKGIRG 93 Query: 910 PAQGDGTSLSPNYTLESTSGNDGKPVSGGGGRGRGRRKRDSGHVSPGTFFDKYSAAPDSG 969 P G +P L G+DG P G G + SPG F P Sbjct: 94 PPGLPGFPGTPG--LPGMPGHDGAPGPQGIPGCNGTKGERGFPGSPG--FPGLQGPP--- 146 Query: 970 GAPGVSPGQQQASGAAVGGSSAGETRGAP----------TPHEKALTSPSWGKGAELLLG 1019 G PG+ PG + G+ + S G +G P P + P G L+G Sbjct: 147 GPPGI-PGMKGEPGSIIMSSLPGP-KGNPGYPGPPGIQGLPGPTGIPGPIGPPGPPGLMG 204 Query: 1020 DQ--PDLIGSLDG------GAKSDSSSPNV-------GEFASDE--VSTSYANEDEVSSS 1062 P L G G K + + G+ + + + + D+ Sbjct: 205 PPGPPGLPGPKGNMGLNFQGPKGEKGEQGLQGPPGPPGQISEQKRPIDVEFQKGDQGLPG 264 Query: 1063 SDNPQALVKASRSPLVTGSPKLPPRGVGAGEHGPKAPPPALGLGIMSNSTSTPDSYGGGG 1122 P P + G P P G GE G + P G P G G Sbjct: 265 DRGPPG------PPGIRGPPG--PPGGEKGEKGEQGEPGKRGKPGKDGENGQPGIPGLPG 316 Query: 1123 GPGHPGTPGLEQVRTPTSSSGAPPPDEIHPLEILQAQIQLQRQQFSISEDQPLGLKG--G 1180 PG+PG PG + + +G P P + I +I E +GL G G Sbjct: 317 DPGYPGEPGRDGEKGQKGDTGPPGPPGL--------VIPRPGTGITIGEKGNIGLPGLPG 368 Query: 1181 KKGE 1184 +KGE Sbjct: 369 EKGE 372 Score = 49.3 bits (116), Expect = 2e-05 Identities = 163/666 (24%), Positives = 208/666 (31%), Gaps = 188/666 (28%) Query: 43 GPPGPVDP-AMSALGEPPILGMNMEPYGFHARGHSELHAGGLQAQPVHGFFGGQQPHHGH 101 GPPGP+DP + + GE G+ P +G+ GL P GQ G Sbjct: 950 GPPGPMDPNLLGSKGEKGEPGLPGIPGVSGPKGYQ-----GLPGDPGQPGLSGQPGLPGP 1004 Query: 102 PGSHHPHQHHPHFGGNFG--GPDPGASCLHGGRLLGYGGAAG--------GLGSQP--PF 149 PG + +P G G GP PG G +G+ G G G+ QP P Sbjct: 1005 PGP----KGNPGLPGQPGLIGP-PGLKGTIGD--MGFPGPQGVEGPPGPSGVPGQPGSPG 1057 Query: 150 AEGYEHMAESQGPESFG-PQRPG-----NLPDFHSSGASSHAVPAPCLPLDQSPNRAASF 203 G + G S G P PG LP + + +V P LP A Sbjct: 1058 LPGQKGDKGDPGISSIGLPGLPGPKGEPGLPGYPGNPGIKGSVGDPGLPGLPGTPGAKGQ 1117 Query: 204 HGLPSSSGSDSHSLEPRRVTNQGAVDSLEYNYPGE----APSGHFDMFSPSDSEGQ---- 255 GLP G+ P+ ++ L PGE GH P +G+ Sbjct: 1118 PGLPGFPGTPGPP-GPKGISGPPGNPGL----PGEPGPVGGGGHPGQPGPPGEKGKPGQD 1172 Query: 256 -LPHYAAGRQVPGG---AFPGASAMPRAAGMVGLSKMHAQPPQQ-QPQQQQQPQQQQQQH 310 +P A + PG PG +P +G G + P P + +P Sbjct: 1173 GIPGPAGQKGEPGQPGFGNPGPPGLPGLSGQKGDGGLPGIPGNPGLPGPKGEPG------ 1226 Query: 311 GVFFERFSGARKMPVGLEPSVGSRHPLMQPPQQAPPPPQQQPPQQPPQQQPPPPPGLLVR 370 F F G + P GS P ++ P+ P P Q PP +P Q P P G Sbjct: 1227 ---FHGFPGVQGPP----GPPGSPGPALEGPKGNPGP--QGPPGRPGFQGLPGPEG---- 1273 Query: 371 QNSCPPALPRPQ--QGEAGTPSGGLQDGGPMLPSQHAQFEYPIHRLENRSMHPYSEPVFS 428 PP LP +GE G P Q G P LP Sbjct: 1274 ----PPGLPGNGGIKGEKGNPG---QPGLPGLPGLKGD---------------------- 1304 Query: 429 MQHPPPQQAPNQRLQHFDAPPYMNVAKRPRFDFPGSAGVDRCASWNGSMHNGALDNHLSP 488 Q PP Q R P +N K G G+ + G + P Sbjct: 1305 -QGPPGLQGNPGR-------PGLNGMK-------GDPGLPGVPGFPGMKGPSGVPGSAGP 1349 Query: 489 SAYPGLPGEFTPPVPDSFPSGPPLQHPAPDHQSLQQQQQQQQQQQQQQQQQQQQQQQQQQ 548 PGL G P GPP P P QS+ + Q Sbjct: 1350 EGEPGLIG----------PPGPP-GLPGPSGQSIIIKGDAGPPGIPGQPG---------- 1388 Query: 549 QQRQNAALMIKQMASRNQQQRLRQPNLAQLGHPGDVGQGGLVHGGPVGGLAQPNFEREGG 608 +K + Q L P G PGD G+ GL P F+ GG Sbjct: 1389 ---------LKGLPGPQGPQGLPGPT----GPPGDPGRNGL-----------PGFDGAGG 1424 Query: 609 STGAGRLGTFEQQAPHLAQESAWFSGPHPPPGDLLPRRMGGSGLPADCGPHDPSLAPPPP 668 G PG LP + G GL GP D PP P Sbjct: 1425 RKG--------------------------DPG--LPGQPGTRGLDGPPGP-DGLQGPPGP 1455 Query: 669 PGGSGV 674 PG S V Sbjct: 1456 PGTSSV 1461 >gi|40068466 AT rich interactive domain 1B (SWI1-like) isoform 1 [Homo sapiens] Length = 2231 Score = 105 bits (261), Expect = 4e-22 Identities = 241/1019 (23%), Positives = 332/1019 (32%), Gaps = 237/1019 (23%) Query: 44 PPGPVDPAMSALGE----PPILGMNMEPYGFHARGHSELHAGGLQAQPV----------- 88 PPGP P +S G+ PP +G EP G H L A G Q PV Sbjct: 115 PPGP--PLLSKPGDEDDAPPKMG---EPAGGRYE-HPGLGALGTQQPPVAVPGGGGGPAA 168 Query: 89 ----HGFFGGQQPHHGHPGSHHPHQHHPHFGGNFGGPDPGASCLHGGRLLGYGGAAGGLG 144 + ++G P G PG + P F + G PG +H AAG G Sbjct: 169 VPEFNNYYGSAAPASGGPGG----RAGPCFDQHGGQQSPGMGMMHSAS----AAAAGAPG 220 Query: 145 SQPPFAEGYEHMAESQGPESFGPQRPGNLPDFHSSGASSHAVPAPCLPLDQSPNRAASFH 204 S P +E SQ G RPG G + Sbjct: 221 SMDPLQNSHEGYPNSQCNHYPGYSRPGAGGGGGGGGGGGGG------------SGGGGGG 268 Query: 205 GLPSSSGSDSHSLEPRRVTNQGAVDSLEYNYPGEAPSGHFDMFSPSDSEGQLPHYAAGRQ 264 G + G+ + ++ A G + +G+ + SP RQ Sbjct: 269 GGAGAGGAGAGAVAAAAAAAAAAAGGGGGGGYGGSSAGYGVLSSP-------------RQ 315 Query: 265 VPGGAFPGASAMPRAAGMVGLSKMHAQPPQQQPQQQQQPQQQQQQHGVFFERFSGARKMP 324 GG G P G LSK A F+RF+G + P Sbjct: 316 QGGGMMMG----PGGGGAASLSKAAAGSAAGG-----------------FQRFAGQNQHP 354 Query: 325 VGLEPSVGSRHPLMQPPQQAPPPPQQQPPQQPPQQQPPPPPGLLVRQNSCPPALPRPQQG 384 G P++ L+ P P + P P PP PP+ P+ Q Sbjct: 355 SGATPTLNQ---LLTSPS---PMMRSYGGSYPEYSSPSAPPP--------PPSQPQSQAA 400 Query: 385 EAGTPSGGLQDGGPMLPSQHAQFEYPIHRLENRSMHPYSEPVFSMQHPPPQQAPNQRLQH 444 AG +GG Q M + +Y + S P S P P +Q Sbjct: 401 AAGAAAGGQQAAAGMGLGKDMGAQYAAASPAWAAAQQRSHPAMSPGTPGPTMGRSQ---- 456 Query: 445 FDAPPYMNVAKRPRFDFPGSAGVDRCASWNGSMHNGALDNHLSP---SAYPGLPGEFTPP 501 +P V KRP+ GS + H P S YPG G + PP Sbjct: 457 -GSPMDPMVMKRPQLYGMGS------------------NPHSQPQQSSPYPG--GSYGPP 495 Query: 502 VPDSFPSGPPLQHPAPDHQSLQQQQQQQQQQQQQQQ------QQQQQQQQQQQQQRQNAA 555 P +P G +Q P + Q QQQ Q QQ QQ QQ QQ Q + Sbjct: 496 GPQRYPIG--IQGRTPGAMAGMQYPQQQMPPQYGQQGVSGYCQQGQQPYYSQQPQPPHLP 553 Query: 556 LMIKQMASRNQQQRLRQPNLAQLGH---------PGDVGQ-----------------GGL 589 + + S++QQ+ Q +++Q G+ PG G Sbjct: 554 PQAQYLPSQSQQRYQPQQDMSQEGYGTRSQPPLAPGKPNHEDLNLIQQERPSSLPDLSGS 613 Query: 590 VHGGPVGGLAQ-PNFEREGGSTGAGRLGTFEQQAPHLAQESAWFS----GPHPPP-GDLL 643 + P G A + GST + + Q+P S S GP P P G + Sbjct: 614 IDDLPTGTEATLSSAVSASGSTSSQGDQSNPAQSPFSPHASPHLSSIPGGPSPSPVGSPV 673 Query: 644 PRRMGGSGLPADCGPHDPSLAPPPPPGGSG------VLFRGPL-QEPMRMPGEGHVPAL- 695 SG P S PP PPG L + P+ QE M G P + Sbjct: 674 GSNQSRSG-PISPASIPGSQMPPQPPGSQSESSSHPALSQSPMPQERGFMAGTQRNPQMA 732 Query: 696 --------------PSPGLQFGGSL-------------------GGLGQLQSPGAGVGLP 722 PSPG Q + G G P A G+P Sbjct: 733 QYGPQQTGPSMSPHPSPGGQMHAGISSFQQSNSSGTYGPQMSQYGPQGNYSRPPAYSGVP 792 Query: 723 SAASERRPPPPDFATSA---LGGQ-PGFPFGA--------AGRQSTPHSGPGVNSPPSAG 770 SA+ P P SA + GQ P P GA AG Q+ P G + PS+ Sbjct: 793 SASYS--GPGPGMGISANNQMHGQGPSQPCGAVPLGRMPSAGMQNRPFPGNMSSMTPSSP 850 Query: 771 GGGGSSGGGGGGGAYPPQPDF-QPSQRTSASKLGALSLGSFNKPSSKDNLFGQSCLAALS 829 G G G G PP P + +Q +A+ + A + + ++ S + +A+ S Sbjct: 851 GMSQQGGPGMG----PPMPTVNRKAQEAAAAVMQAAANSAQSRQGSFPGMNQSGLMASSS 906 Query: 830 TACQNMIASLGAPNLNVTFNKKNPPEGKRKLSQNETD---GAAVAGNPGSDYFP-----G 881 Q M N + N + PP N + G A +PG P Sbjct: 907 PYSQPM------NNSSSLMNTQAPPYSMAPAMVNSSAASVGLADMMSPGESKLPLPLKAD 960 Query: 882 GTAPGAPGPGGPSGTSSSGSKASGPPNPPAQGDGTSLSP-NYTLESTSGNDGKPVSGGG 939 G G P P S S S S PP P + +SP + ++ S G++ +S G Sbjct: 961 GKEEGTPQPESKSKDSYSSQGISQPPTPGNLPVPSPMSPSSASISSFHGDESDSISSPG 1019 Score = 95.1 bits (235), Expect = 4e-19 Identities = 168/663 (25%), Positives = 217/663 (32%), Gaps = 145/663 (21%) Query: 514 HPAPDHQSLQQQQQQQQQQQQQQQQQQQQQQQQQQQQRQNAALMIKQMASRNQQQRLRQP 573 H H +LQQQ Q QQQQQQQQQQQQQQQQQQ N +L Sbjct: 40 HHLHHHHALQQQLNQFQQQQQQQQQQQQQQQQQQHPISNNNSL----------------- 82 Query: 574 NLAQLGHPGDVGQGGLVHGGPVGGLAQPNFERE----GGSTGAGRLGTFEQQAPHLAQES 629 GG GG QP + E GG+ + G + P L + Sbjct: 83 ------------------GGAGGGAPQPGPDMEQPQHGGAKDSAAGGQADPPGPPLLSKP 124 Query: 630 AWFSGPHPPPGDLLPRRMGGSGLPADCGPHDPSLAPPPPPGGSGVLFRGPLQEPMRMPGE 689 P G+ R GL A G P P PGG G GP P Sbjct: 125 GDEDDAPPKMGEPAGGRYEHPGLGA-LGTQQP---PVAVPGGGG----GPAAVPEFNNYY 176 Query: 690 GH-VPALPSPGLQFGGSLGGLGQLQSPGAG-VGLPSAASERRPPPPDFATSALGGQPGFP 747 G PA PG + G G QSPG G + SAA+ P D ++ G P Sbjct: 177 GSAAPASGGPGGRAGPCFDQHGGQQSPGMGMMHSASAAAAGAPGSMDPLQNSHEGYPNSQ 236 Query: 748 FGAAGRQSTPHSGPGVNSPPSAGGGGGSSGGGGGGGAYPPQPDFQPSQRTSASKLGALSL 807 S P +G G GGGGGS GGGGGGGA GA Sbjct: 237 CNHYPGYSRPGAGGGGGG--GGGGGGGSGGGGGGGGA------------------GAGGA 276 Query: 808 GSFNKPSSKDNLFGQSCLAALSTACQNMIASLGAPNLNVTFNKKNPPEGKRKLSQNETDG 867 G+ A++ A A+ G G + G Sbjct: 277 GA----------------GAVAAAAAAAAAAAGG--------------GGGGGYGGSSAG 306 Query: 868 AAVAGNPGSDYFPGGTAPGAPGPGGPSGTS--SSGSKASGPPNPPAQGDGTS-LSPNYTL 924 V +P GG PG GG + S ++GS A G Q S +P Sbjct: 307 YGVLSSPRQQ---GGGMMMGPGGGGAASLSKAAAGSAAGGFQRFAGQNQHPSGATPTLNQ 363 Query: 925 ESTSGNDGKPVSGGGGRGRGRRKRDSGHVSPGTFFDKYSAAPDSGGAPGVSPGQQQASGA 984 TS + GG + +YS+ P Q A+GA Sbjct: 364 LLTSPSPMMRSYGGS-------------------YPEYSSPSAPPPPPSQPQSQAAAAGA 404 Query: 985 AVGG--SSAGETRGAPTPHEKALTSPSWGKGAELLLGDQPDLIGSLDGGAKSDSSSPNVG 1042 A GG ++AG G + A SP+W + P + G P +G Sbjct: 405 AAGGQQAAAGMGLGKDMGAQYAAASPAWAAAQQ---RSHPAMSPGTPG--------PTMG 453 Query: 1043 EFASDEVSTSYANEDEVSSSSDNPQALVKASRSPLVTGSPKLPPRGVGAGEHGPKAPPPA 1102 + ++ NP + + S SP GS P G G + P Sbjct: 454 RSQGSPMDPMVMKRPQLYGMGSNPHSQPQQS-SPYPGGS--YGPPGPQRYPIGIQGRTPG 510 Query: 1103 LGLGIMSNSTSTPDSYGGGGGPGHPGTPGLEQVRTPTSSSGAPPPDEIHPLEILQAQIQL 1162 G+ P YG G G+ +Q + P S PP + L +Q Q Sbjct: 511 AMAGMQYPQQQMPPQYGQQGVSGY-----CQQGQQPYYSQQPQPPHLPPQAQYLPSQSQQ 565 Query: 1163 QRQ 1165 + Q Sbjct: 566 RYQ 568 Score = 82.8 bits (203), Expect = 2e-15 Identities = 181/796 (22%), Positives = 249/796 (31%), Gaps = 114/796 (14%) Query: 31 NTHFKAPAFHTGGPPGPVDPAMSALGEPPILGMNMEPYGFHARGHSELHAGGLQAQPVHG 90 N ++ + A +GGP G P G GM M +H+ A G Sbjct: 173 NNYYGSAAPASGGPGGRAGPCFDQHGGQQSPGMGM------------MHSASAAAAGAPG 220 Query: 91 FFGG-QQPHHGHPGS---HHPHQHHPHFGGNFGGPDPGASCLHGGRLLGYGGAAG-GLGS 145 Q H G+P S H+P P GG GG G GG G GA G G G+ Sbjct: 221 SMDPLQNSHEGYPNSQCNHYPGYSRPGAGGGGGGGGGGGGGSGGGGGGGGAGAGGAGAGA 280 Query: 146 QPPFAEGYEHMAESQGPESFGPQRPG----NLPDFHSSGASSHAVPAPCLPLDQSPNRAA 201 A A G +G G + P G L ++ +A Sbjct: 281 VAAAAAAAAAAAGGGGGGGYGGSSAGYGVLSSPRQQGGGMMMGPGGGGAASLSKAAAGSA 340 Query: 202 SFHGLPSSSGSDSHSLEPRRVTNQ--GAVDSLEYNYPGEAPSGHFDMFSPSDSEGQLPHY 259 + G +G + H NQ + + +Y G P + +P Q Sbjct: 341 A-GGFQRFAGQNQHPSGATPTLNQLLTSPSPMMRSYGGSYPE-YSSPSAPPPPPSQPQSQ 398 Query: 260 AAGRQVPGGAFPGASAMPRAAGMVGLSKMHAQPPQQQPQQQQQPQQQQQQHGVFFERFSG 319 AA G A+ M M G A P QQ+ P G R G Sbjct: 399 AAAAGAAAGGQQAAAGMGLGKDM-GAQYAAASPAWAAAQQRSHPAMSPGTPGPTMGRSQG 457 Query: 320 ARKMPVGLEP----SVGSRHPLMQPPQQA--------PPPPQQQP------------PQQ 355 + P+ ++ +GS +P QP Q + PP PQ+ P Q Sbjct: 458 SPMDPMVMKRPQLYGMGS-NPHSQPQQSSPYPGGSYGPPGPQRYPIGIQGRTPGAMAGMQ 516 Query: 356 PPQQQPPPPPGLLVRQNSCPPALPRPQQGEAGTPSGGLQDGGPMLPSQHAQFEYPIHRLE 415 PQQQ PP G C +P + P L LPSQ Q P + Sbjct: 517 YPQQQMPPQYGQQGVSGYCQQG-QQPYYSQQPQPP-HLPPQAQYLPSQSQQRYQPQQDMS 574 Query: 416 NRSMHPYSEPVFS-----------MQHPPPQQAPNQRLQHFDAPPYMNVAKRPRFDFPGS 464 S+P + +Q P P+ D P GS Sbjct: 575 QEGYGTRSQPPLAPGKPNHEDLNLIQQERPSSLPDLSGSIDDLPTGTEATLSSAVSASGS 634 Query: 465 AGVDRCASWNGSMHNGA---LDNHLSP--SAYPGLPGEFTPPVPDSFPSGPPLQHPAP-D 518 S G N A H SP S+ PG P P P P G P Sbjct: 635 ------TSSQGDQSNPAQSPFSPHASPHLSSIPGGPS----PSPVGSPVGSNQSRSGPIS 684 Query: 519 HQSLQQQQQQQQQQQQQQQQQQQQQQQQQQQQRQNAALMIKQMASRNQQQRLRQPNLAQL 578 S+ Q Q Q + Q ++ + Q + Q +Q + Sbjct: 685 PASIPGSQMPPQPPGSQSESSSHPALSQSPMPQERGFMAGTQRNPQMAQYGPQQTGPSMS 744 Query: 579 GHPGDVGQGGLVHGGPVGGLAQPNFEREGG--STGAGRLGTFEQQAPHLAQESAWFSGPH 636 HP GG +H G + Q N G + G G + + + SA +SGP Sbjct: 745 PHP---SPGGQMHAG-ISSFQQSNSSGTYGPQMSQYGPQGNYSRPPAYSGVPSASYSGPG 800 Query: 637 PPPGDLLPRRMGGSGLPADCGPHDPSLAPPPPPGGSGVLFRGPLQEPMRMPGEGHVPALP 696 P G +M G G P P G+ L R P P G++ ++ Sbjct: 801 PGMGISANNQMHGQG--------------PSQPCGAVPLGRMPSAGMQNRPFPGNMSSMT 846 Query: 697 SPGLQFGGSLGGLGQLQSPGAGVGLPS-------AASERRPPPPDFATSALGGQPGFPFG 749 S G+ Q PG G +P+ AA+ + A S G PG Sbjct: 847 P-------SSPGMSQQGGPGMGPPMPTVNRKAQEAAAAVMQAAANSAQSRQGSFPGMNQS 899 Query: 750 AAGRQSTPHSGPGVNS 765 S+P+S P NS Sbjct: 900 GLMASSSPYSQPMNNS 915 Score = 68.2 bits (165), Expect = 5e-11 Identities = 125/504 (24%), Positives = 179/504 (35%), Gaps = 69/504 (13%) Query: 703 GGSLGGLGQ----LQSPGAGVGLPSAASERRPPPPDFATSALGGQPGFP----FGAAGRQ 754 GG+ GG Q ++ P G SAA + PP S G + P A GR Sbjct: 83 GGAGGGAPQPGPDMEQPQHGGAKDSAAGGQADPPGPPLLSKPGDEDDAPPKMGEPAGGRY 142 Query: 755 STPHSGP-GVNSPPSAGGGGGSSGGGGGGGAYPPQPDFQPSQRTSASKLGALSLGSFNKP 813 P G G PP A GGGGG A P ++ S ++ G + F++ Sbjct: 143 EHPGLGALGTQQPPVA-----VPGGGGGPAAVPEFNNYYGSAAPASGGPGGRAGPCFDQH 197 Query: 814 SSKDNLFGQSCLAALSTACQNMIASLGAPNLNVTFNKKNPPEGKRKLSQNETDGAAVAGN 873 + + G + + S A + GAP G QN +G N Sbjct: 198 GGQQSP-GMGMMHSASAA------AAGAP-------------GSMDPLQNSHEGYP---N 234 Query: 874 PGSDYFPGGTAPGAPGPGGPSGTSSSGSKASGPPNPPAQGDGTSLSPNYTLESTSGNDGK 933 +++PG + PGA G GG G GS G G G + + + + Sbjct: 235 SQCNHYPGYSRPGAGGGGGGGGGGGGGSGGGGGGG----GAGAGGAGAGAVAAAAAAAAA 290 Query: 934 PVSGGGGRGRGRRKRDSGHVS-PGTFFDKYSAAPDSGGAPGVSPGQQQASGAAVGGSS-- 990 GGGG G G G +S P P GGA +S + A+G+A GG Sbjct: 291 AAGGGGGGGYGGSSAGYGVLSSPRQQGGGMMMGPGGGGAASLS---KAAAGSAAGGFQRF 347 Query: 991 AGETR---GAPTPHEKALTSPS---WGKGAELLLGDQPDLIGSLDGGAKSDSSSPNVGEF 1044 AG+ + GA + LTSPS G P +S +++ Sbjct: 348 AGQNQHPSGATPTLNQLLTSPSPMMRSYGGSYPEYSSPSAPPPPPSQPQSQAAAAGAAAG 407 Query: 1045 ASDEVSTSYANEDEVSSSSDNPQALVKASRSPLVTGSPKLPPRGVGAGEHGPKAP----- 1099 + +D + + A A + SP P +G + P P Sbjct: 408 GQQAAAGMGLGKDMGAQYAAASPAWAAAQQRSHPAMSPGTPGPTMGRSQGSPMDPMVMKR 467 Query: 1100 PPALGLGIMSNSTSTPDS---YGGG--GGPGHPGTPGLEQVRTPTSSSGAPPPDEIHPLE 1154 P G+G SN S P Y GG G PG P Q RTP + +G P + P + Sbjct: 468 PQLYGMG--SNPHSQPQQSSPYPGGSYGPPGPQRYPIGIQGRTPGAMAGMQYPQQQMPPQ 525 Query: 1155 ILQAQI----QLQRQQFSISEDQP 1174 Q + Q +Q + + QP Sbjct: 526 YGQQGVSGYCQQGQQPYYSQQPQP 549 Score = 57.8 bits (138), Expect = 7e-08 Identities = 235/1074 (21%), Positives = 314/1074 (29%), Gaps = 206/1074 (19%) Query: 335 HPLMQPPQQAPPPPQQQPPQQPPQQQPPPPPGLLVRQNSCPPALPRPQQGEAGTPSGGLQ 394 H L Q Q QQQ QQ QQQ P + NS G GG Sbjct: 46 HALQQQLNQFQQQQQQQQQQQQQQQQQQHP---ISNNNSL------------GGAGGGAP 90 Query: 395 DGGPMLPSQHAQFEYPIHRLENRSMHPYSEPVFSMQHPPPQQAPNQRLQHFDAPPYMNVA 454 GP E P H S PP ++ DAPP M Sbjct: 91 QPGP-------DMEQPQHGGAKDSA------AGGQADPPGPPLLSKPGDEDDAPPKMGEP 137 Query: 455 KRPRFDFPGSAGVDRCASWNGSMHNGALDNHLSPSAYPGLPG--EFTPPVPDSFPSGPPL 512 R++ PG GAL P A PG G P + + S P Sbjct: 138 AGGRYEHPGL---------------GALGTQQPPVAVPGGGGGPAAVPEFNNYYGSAAPA 182 Query: 513 QHPAPDHQSLQQQQQQQQQQQQQQQQQQQQQQQQQQQQRQNAALMIKQMASRNQQQRLRQ 572 P ++ Q QQ L N Q Sbjct: 183 SG-GPGGRAGPCFDQHGGQQSPGMGMMHSASAAAAGAPGSMDPLQNSHEGYPNSQCN-HY 240 Query: 573 PNLAQLGHPGDVGQGGLVHGGPVGGLAQPNFEREGGSTGAGRLGTFEQQAPHLAQESA-- 630 P ++ G G G GG GG GG GG GAG G A A +A Sbjct: 241 PGYSRPGAGGGGGGGGGGGGGSGGGGG-------GGGAGAGGAGAGAVAAAAAAAAAAAG 293 Query: 631 -----WFSGPHPPPGDLLPRRMGGSGL---PADCGPHDPSLAPPPPPGGSGVLFRGPLQE 682 + G G L R G G+ P G S A G F G Q Sbjct: 294 GGGGGGYGGSSAGYGVLSSPRQQGGGMMMGPGGGGAASLSKAAAGSAAGGFQRFAGQNQH 353 Query: 683 PM-RMPGEGHVPALPSPGLQ-FGGSL-----------------------GGLGQLQSPGA 717 P P + PSP ++ +GGS G Q A Sbjct: 354 PSGATPTLNQLLTSPSPMMRSYGGSYPEYSSPSAPPPPPSQPQSQAAAAGAAAGGQQAAA 413 Query: 718 GVGLPS-------------AASERRPPP---PDFATSALGGQPGFPFGAA--------GR 753 G+GL AA+++R P P +G G P G Sbjct: 414 GMGLGKDMGAQYAAASPAWAAAQQRSHPAMSPGTPGPTMGRSQGSPMDPMVMKRPQLYGM 473 Query: 754 QSTPHSGPGVNSPPSAGGGG------------GSSGGGGGGGAYPPQPDFQPSQRTSASK 801 S PHS P +SP G G G + G G YP Q P Q Sbjct: 474 GSNPHSQPQQSSPYPGGSYGPPGPQRYPIGIQGRTPGAMAGMQYPQQQ--MPPQYGQQGV 531 Query: 802 LGALSLGS---FNKPSSKDNLFGQSCLAALSTACQNMIASLGAPNLNVTFNKKNPPEGKR 858 G G +++ +L Q+ L + Q + + PP Sbjct: 532 SGYCQQGQQPYYSQQPQPPHLPPQA--QYLPSQSQQRYQPQQDMSQEGYGTRSQPPLAPG 589 Query: 859 K-------LSQNETDGAAVAGNPGSDYFPGGTAPGAPGPGGPSGTSSSGSKASGPPNPPA 911 K L Q E + + D P GT SG++SS S P P Sbjct: 590 KPNHEDLNLIQQERPSSLPDLSGSIDDLPTGTEATLSSAVSASGSTSSQGDQSNPAQSP- 648 Query: 912 QGDGTSLSPNYTLESTSGNDGKPVSGGGGRGRGRRKRDSGHVSPGTFFDKYSAAPDSGGA 971 SP+ + S G P G G + SG +SP A+ Sbjct: 649 ------FSPHAS-PHLSSIPGGPSPSPVGSPVGSNQSRSGPISP--------ASIPGSQM 693 Query: 972 PGVSPGQQQASGAAVGGSSAGETRGAPTPHEKALTSPSWGKGAELLLGDQPDLIGSLDGG 1031 P PG Q S SS +P P E+ + + G Q G Sbjct: 694 PPQPPGSQSES------SSHPALSQSPMPQERGFMAGTQRNPQMAQYGPQQT------GP 741 Query: 1032 AKSDSSSPN------VGEFASDEVSTSYANEDEVSSSSDNPQALVKASRSPLVTGSPKLP 1085 + S SP + F S +Y + S PQ SR P +G P Sbjct: 742 SMSPHPSPGGQMHAGISSFQQSNSSGTYGPQ----MSQYGPQG--NYSRPPAYSGVPSAS 795 Query: 1086 PRGVGAGE----------HGPKAPPPALGLGIMSNSTSTPDSYGGGGGPGHPGTPGLEQV 1135 G G G GP P A+ LG M ++ + G P +PG+ Q Sbjct: 796 YSGPGPGMGISANNQMHGQGPSQPCGAVPLGRMPSAGMQNRPFPGNMSSMTPSSPGMSQQ 855 Query: 1136 RTPTSSSGAPPP------DEIHPLEILQAQIQLQRQQFSISEDQPLGLKGGKK--GECAV 1187 P G P P E + A Q +Q S GL + Sbjct: 856 GGP--GMGPPMPTVNRKAQEAAAAVMQAAANSAQSRQGSFPGMNQSGLMASSSPYSQPMN 913 Query: 1188 GASGAQNGDSELGSCCSEAVKSAMSTIDLDSLMAEHSAAWYMPADKALVDSADDDKTLAP 1247 +S N + S V S+ +++ L +M+ + +P AD + P Sbjct: 914 NSSSLMNTQAPPYSMAPAMVNSSAASVGLADMMSPGESKLPLPL------KADGKEEGTP 967 Query: 1248 WEKAKPQNPNSKEAHDLPANKASASQPGSHLQCLSVHCTDDVGDAKARASVPTW 1301 ++K ++ S + P + P S + S + GD S P W Sbjct: 968 QPESKSKDSYSSQGISQPPTPGNLPVP-SPMSPSSASISSFHGDESDSISSPGW 1020 Score = 56.2 bits (134), Expect = 2e-07 Identities = 109/462 (23%), Positives = 164/462 (35%), Gaps = 81/462 (17%) Query: 95 QQPHHGHPGSHHPHQHHPHFGGNFGGPDPG-------ASCLHGGRLLGYGGAAGGLGSQP 147 Q P + GS Q G N PG AS HG GG + + Sbjct: 1161 QPPSPANSGSLQGPQTPQSTGSNSMAEVPGDLKPPTPASTPHGQMTPMQGGRSSTISVHD 1220 Query: 148 PFAEGYEHMAESQGPE--SFGPQRPGNLPDFHSSGASSHAVPAPCLPLDQSPNRAASFHG 205 PF++ +++S P+ S P P + G S +P + PN+ F G Sbjct: 1221 PFSD----VSDSSFPKRNSMTPNAP------YQQGMS---MPDVMGRMPYEPNKDP-FGG 1266 Query: 206 LPSSSGSDSHSLEPRRVTNQGAVDSLEYNYPGEAPSGHFDMFSPSDSEGQLPHYAA---- 261 + GS + ++ N D YN ++PSG + Q P+ A+ Sbjct: 1267 MRKVPGSSEPFMTQGQMPNSSMQDM--YN---QSPSGAMSNLGMGQRQ-QFPYGASYDRR 1320 Query: 262 ----GRQVPGGAFPGASAMPRAAGMVGLS------KMHAQ----PPQQQPQ----QQQQP 303 G+Q PG P + P GL K H PP ++ + Q Sbjct: 1321 HEPYGQQYPGQG-PPSGQPPYGGHQPGLYPQQPNYKRHMDGMYGPPAKRHEGDMYNMQYS 1379 Query: 304 QQQQQQHGVFFERFSGARKMPV-GLEPSVGSRHPLMQPPQ---QAPPPPQQQPPQQPPQQ 359 QQQ+ + + +SG + P+ G P SR + P Q PP P Q Sbjct: 1380 SQQQEMYNQYGGSYSGPDRRPIQGQYPYPYSRERMQGPGQIQTHGIPPQMMGGPLQSSSS 1439 Query: 360 QPPPPPGLLVRQNSCPPALPRPQQGEAGTPSGGLQDGGPMLPSQHAQFEY--PIHRLENR 417 + P R + +P P Q G P G Q P P + + P R+ + Sbjct: 1440 EGPQQNMWAARND-----MPYPYQNRQG-PGGPTQ--APPYPGMNRTDDMMVPDQRINHE 1491 Query: 418 SMHPYSEPVFSMQHPPPQQAPNQRLQHFDAPPYMNVAKRPRFDFPGSAGVDRCASWNGSM 477 S P + P + + +Q PP +P + P S + + + Sbjct: 1492 SQWPSH-----VSQRQPYMSSSASMQPITRPP------QPSYQTPPSLPNHISRAPSPAS 1540 Query: 478 HNGALDNHLSPSAYPGLPG----EFTPPVPDSFPSGPPLQHP 515 +L+N +SPS P LP + P VP S +GPP Q P Sbjct: 1541 FQRSLENRMSPSKSPFLPSMKMQKVMPTVPTSQVTGPPPQPP 1582 Score = 41.6 bits (96), Expect = 0.005 Identities = 33/102 (32%), Positives = 40/102 (39%), Gaps = 14/102 (13%) Query: 294 QQQPQQQQQPQQQQQQHGVFFERFSGARKMPVGLEPSVGSRHPLMQPPQQAPPPPQQQPP 353 QQQ QQQQQ QQQQQQH + G G P P + P + Sbjct: 58 QQQQQQQQQQQQQQQQHPISNNNSLG----------GAGGGAPQPGPDMEQPQHGGAKDS 107 Query: 354 QQPPQQQPPPPPGLLVR---QNSCPPALPRPQQGEAGTPSGG 392 Q PP PP LL + ++ PP + P G P G Sbjct: 108 AAGGQADPPGPP-LLSKPGDEDDAPPKMGEPAGGRYEHPGLG 148 Score = 36.2 bits (82), Expect = 0.21 Identities = 39/161 (24%), Positives = 64/161 (39%), Gaps = 12/161 (7%) Query: 638 PPGDLLPRRMGGSGLPADCGPHDP--SLAPPPPPGGSGVLFRGPLQEPMRMPGE-GHVPA 694 P G + P + G S + HDP ++ P + + P Q+ M MP G +P Sbjct: 1201 PHGQMTPMQGGRS---STISVHDPFSDVSDSSFPKRNSMTPNAPYQQGMSMPDVMGRMPY 1257 Query: 695 LPSPGLQFGGSLGGLGQLQSPGAGVGLPSAASE---RRPPPPDFATSALGGQPGFPFGAA 751 P+ FGG G + +P+++ + + P + +G + FP+GA+ Sbjct: 1258 EPNKD-PFGGMRKVPGSSEPFMTQGQMPNSSMQDMYNQSPSGAMSNLGMGQRQQFPYGAS 1316 Query: 752 GRQSTPHSGPGVNSPPSAGGGGGSSGGGGGGGAYPPQPDFQ 792 H G P G GG G YP QP+++ Sbjct: 1317 --YDRRHEPYGQQYPGQGPPSGQPPYGGHQPGLYPQQPNYK 1355 Score = 33.1 bits (74), Expect = 1.8 Identities = 81/347 (23%), Positives = 117/347 (33%), Gaps = 83/347 (23%) Query: 51 AMSALGEPPILGMNME-PYGFHARGHSELHAGGLQAQPVHGFFGGQQPHHGHPGSHHPHQ 109 AMS LG +G + PYG + H Q P G GQ P+ GH +P Q Sbjct: 1299 AMSNLG----MGQRQQFPYG---ASYDRRHEPYGQQYPGQGPPSGQPPYGGHQPGLYPQQ 1351 Query: 110 --HHPHFGGNFGGPDPGASCLHGGRLLG-------------YGGAAGGLGSQPPFAEGYE 154 + H G +G P + H G + YGG+ G +P Sbjct: 1352 PNYKRHMDGMYGPP----AKRHEGDMYNMQYSSQQQEMYNQYGGSYSGPDRRP------- 1400 Query: 155 HMAESQGPESFGPQR---PGNLPDFHSSGASSHAVPAPCLPLDQSPNRAASFHGLPSSSG 211 + Q P + +R PG + +H +P + P +++S G + Sbjct: 1401 --IQGQYPYPYSRERMQGPGQI--------QTHGIPPQMM---GGPLQSSSSEGPQQNMW 1447 Query: 212 SDSHSLEPRRVTNQGAVDSLEY-NYPGEAPSGHFDMFSPS---DSEGQLPHYAAGRQVPG 267 + + + QG + YPG + DM P + E Q P + + RQ Sbjct: 1448 AARNDMPYPYQNRQGPGGPTQAPPYPGMNRTD--DMMVPDQRINHESQWPSHVSQRQ--- 1502 Query: 268 GAFPGASAMPRAAGMVGLSKMHAQPPQQQPQQQQQPQQQQQQH-GVFFERFSGARKMPVG 326 M +A M QP + PQ Q H S R + Sbjct: 1503 ------PYMSSSASM--------QPITRPPQPSYQTPPSLPNHISRAPSPASFQRSLENR 1548 Query: 327 LEPSVGSRHPLMQPPQQAPPPPQQQPPQQPPQQQPPP-------PPG 366 + PS P M+ + P P Q PP QPPP PPG Sbjct: 1549 MSPSKSPFLPSMKMQKVMPTVPTSQVTGPPP--QPPPIRREITFPPG 1593 >gi|110349772 alpha 1 type I collagen preproprotein [Homo sapiens] Length = 1464 Score = 104 bits (259), Expect = 6e-22 Identities = 292/1206 (24%), Positives = 376/1206 (31%), Gaps = 234/1206 (19%) Query: 43 GPPGPVDPAMSALGEPPILGMNMEPYGFHARGHSELHAGGLQAQPVHGFFGGQQPHH--G 100 GPPGP P PP LG N P + G+ E GG+ V G G P G Sbjct: 142 GPPGPPGPP-----GPPGLGGNFAPQLSY--GYDEKSTGGIS---VPGPMGPSGPRGLPG 191 Query: 101 HPGSHHPHQHHPHFGGNFGGPDPGASCLHGGRLLGYGGAAGGLGSQ-PPFAEGYEHMAES 159 PG+ P F GP PG G GA+G +G + PP G Sbjct: 192 PPGAPGPQ--------GFQGP-PGEP--------GEPGASGPMGPRGPPGPPG----KNG 230 Query: 160 QGPESFGPQRPGNLPDFHSSGASSHAVPAPC-LPLDQSPNRAASFHGLPSSSGSDSHSLE 218 E+ P RPG GA +P LP + + G +G E Sbjct: 231 DDGEAGKPGRPGERGPPGPQGA--RGLPGTAGLPGMKGHRGFSGLDGAKGDAGPAGPKGE 288 Query: 219 PRRVTNQGAVDSL-EYNYPGEAPSGHFDMFSPSDSEGQLPHYAAGRQVPGGAFPGASAMP 277 P GA + PGE G P+ + G A G P G G + P Sbjct: 289 PGSPGENGAPGQMGPRGLPGER--GRPGAPGPAGARGN--DGATGAAGPPGP-TGPAGPP 343 Query: 278 RAAGMVGLSKMHAQPPQQQPQQQQQPQQQQQQHGVFFERFSGARKMPVGLEPSVGSRHPL 337 G VG +K A P Q P+ + PQ + + G + G + G++ Sbjct: 344 GFPGAVG-AKGEAGP--QGPRGSEGPQGVRGEPGPPGPAGAAGPAGNPGADGQPGAKGAN 400 Query: 338 MQPP-QQAPPPPQQQPPQQPPQQQPPPPPGLLVRQNSCPPALPRPQQGEAGTPSGGLQDG 396 P AP P + P P Q P PPG P+ GE G P G Sbjct: 401 GAPGIAGAPGFPGARGPSGP--QGPGGPPG------------PKGNSGEPGAPGSKGDTG 446 Query: 397 GPMLPSQHAQFEYPIHRLENRSMHPYSEPVFSMQHPPPQQAPNQRLQHFDAPPYMNVAKR 456 P P E EP + PP + + F + K Sbjct: 447 AKGEPGPVGVQGPPGPAGEEGKRGARGEPGPTGLPGPPGERGGPGSRGFPGADGVAGPKG 506 Query: 457 PRFD--FPGSAGVDRCASWNGSMHNGALDNHLSPSAYPGLPGEFTPPVPDSFPSGPPLQH 514 P + PG AG G L + PG PG P + P GP Q Sbjct: 507 PAGERGSPGPAGPKGSPGEAGRPGEAGLPGAKGLTGSPGSPG----PDGKTGPPGPAGQD 562 Query: 515 PAPDHQSLQQQQQQQQQQQQQQQQQQQQQQQQQQQQRQNAALMIKQMASRNQQQRLRQPN 574 P +R Q + P Sbjct: 563 GRPGPPG--------------------------------------PPGARGQAGVMGFPG 584 Query: 575 -LAQLGHPGDVGQGGLVHGGPVGGLAQPNFEREGGSTG----AGRLGTFEQQAPHLAQES 629 G PG G+ G+ GP G + + E G+ G AG G +Q P + Sbjct: 585 PKGAAGEPGKAGERGVP--GPPGAVGPAGKDGEAGAQGPPGPAGPAGERGEQGPAGSPGF 642 Query: 630 AWFSGPHPPPGDLLPRRMGGSGLPADCGPHDPSLAPPP-----------PPGGSGVLFRG 678 GP PPG+ + G G+P D G PS A PPG +G RG Sbjct: 643 QGLPGPAGPPGEA--GKPGEQGVPGDLGAPGPSGARGERGFPGERGVQGPPGPAGP--RG 698 Query: 679 PLQEPMRMPGEGHVPALPSPGLQFGGSLGGLGQLQSPG--AGVGLPSAASERRPPPPDFA 736 P +G A +PG Q L G+ PG GLP +R P A Sbjct: 699 ANGAPGNDGAKGDAGAPGAPGSQGAPGLQGM-----PGERGAAGLPGPKGDRGDAGPKGA 753 Query: 737 TSALG-----------GQPGFPFGAAGRQSTPHSGP-GVNSPPSAGGGGGSSGGGG---- 780 + G G PG P GA G + SGP G P A G G G G Sbjct: 754 DGSPGKDGVRGLTGPIGPPG-PAGAPGDKG--ESGPSGPAGPTGARGAPGDRGEPGPPGP 810 Query: 781 GGGAYPPQPDFQPSQRTSASKLGALSLGSFNKPSSKDNLFGQSCLAALSTACQNMIASLG 840 G A PP D QP + GA P+ G I ++G Sbjct: 811 AGFAGPPGADGQPGAKGEPGDAGAKGDAGPPGPAGPAGPPGP-------------IGNVG 857 Query: 841 APNLNVTFNKKNPPEGKRKLSQNETDGAAVAGNPGSDYFPGGTA--PGAPGPGGPSG--- 895 AP PP + A G PG P G A PG PGP G G Sbjct: 858 APGAKGARGSAGPPG-----ATGFPGAAGRVGPPG----PSGNAGPPGPPGPAGKEGGKG 908 Query: 896 ----TSSSGSKAS-GPPNPPAQGDGTSLSPNYTLESTSGNDGKPVSGG--GGRG----RG 944 T +G GPP PP G SP + +G G P G G RG G Sbjct: 909 PRGETGPAGRPGEVGPPGPPGPA-GEKGSPG--ADGPAGAPGTPGPQGIAGQRGVVGLPG 965 Query: 945 RRKRDSGHVSPGTFFDKYSAAPDSG----------GAPGVS--PGQQQASGAAVGGSSAG 992 +R PG + P G PG++ PG+ GA S G Sbjct: 966 QRGERGFPGLPGPSGEPGKQGPSGASGERGPPGPMGPPGLAGPPGESGREGAPGAEGSPG 1025 Query: 993 ETRGAPTPHEKALTSPSWGKGAELLLGDQPDLIGSLDGGAKSDSSSPN-----VGEFASD 1047 ++ T P+ GA G P +G + P VG + Sbjct: 1026 RDGSPGAKGDRGETGPAGPPGAPGAPG-APGPVGPAGKSGDRGETGPAGPAGPVGPVGAR 1084 Query: 1048 EVSTSYANEDEVSSSSDNPQALVKASRSPLVTGSPKLPPRGVG-------AGEHGPKAPP 1100 + + + + +K R P PP G +G GP+ PP Sbjct: 1085 GPAGPQGPRGDKGETGEQGDRGIKGHRGFSGLQGPPGPPGSPGEQGPSGASGPAGPRGPP 1144 Query: 1101 PALG-------------LGIMSNSTSTPDS--YGGGGGPGHPGTPGLEQVRTPTSSSGAP 1145 + G +G T D+ G G PG PG PG S P Sbjct: 1145 GSAGAPGKDGLNGLPGPIGPPGPRGRTGDAGPVGPPGPPGPPGPPGPPSAGFDFSFLPQP 1204 Query: 1146 PPDEIH 1151 P ++ H Sbjct: 1205 PQEKAH 1210 Score = 99.0 bits (245), Expect = 3e-20 Identities = 219/905 (24%), Positives = 273/905 (30%), Gaps = 167/905 (18%) Query: 326 GLEPSVGSRHPLMQPPQQAPPPPQQQPPQQPPQQQPPPPPGLLVRQNSCPPAL-----PR 380 G+E G P P A PP + P QP PP PPG PP L P+ Sbjct: 109 GVEGPKGDTGP-RGPRGPAGPPGRDGIPGQPGLPGPPGPPG-----PPGPPGLGGNFAPQ 162 Query: 381 PQQGEAGTPSGGLQDGGPMLPSQHAQFEYPIHRLENRSMHPYSEPVFSMQHPPPQQAPNQ 440 G +GG+ GPM PS P P AP Sbjct: 163 LSYGYDEKSTGGISVPGPMGPSGPRGL------------------------PGPPGAPGP 198 Query: 441 RLQHFDAPPYMNVAKRPRFDFPGSAGVDRCASWNGSMHNGALDNHLSPSAYPGLPGEFTP 500 Q F PP PG G G + + PG PGE P Sbjct: 199 --QGFQGPP----------GEPGEPGASGPMGPRGPPGPPGKNGDDGEAGKPGRPGERGP 246 Query: 501 PVPDSFPSGPPLQHPAPDHQSLQQQQQQQQQQQQQQQQQQQQQQQQQQQQRQNAALMIKQ 560 P P G P P ++ + + + + +N A Q Sbjct: 247 PGPQG-ARGLPGTAGLP---GMKGHRGFSGLDGAKGDAGPAGPKGEPGSPGENGA--PGQ 300 Query: 561 MASRNQQQRLRQPNLAQLGHPGDVG-------QGGLVHGGPVGGLAQPNFEREGGSTG-A 612 M R +P G PG G G GP G P F G+ G A Sbjct: 301 MGPRGLPGERGRP-----GAPGPAGARGNDGATGAAGPPGPTGPAGPPGFPGAVGAKGEA 355 Query: 613 GRLGTFEQQAPHLAQES------AWFSGPHPPPG-DLLPRRMGGSGLP------------ 653 G G + P + A +GP PG D P G +G P Sbjct: 356 GPQGPRGSEGPQGVRGEPGPPGPAGAAGPAGNPGADGQPGAKGANGAPGIAGAPGFPGAR 415 Query: 654 ADCGPHDPSLAPPPPPGGSGVLFRGPLQEPMRMPGEGHVPALPSPG-LQFGGSLGGLGQL 712 GP P PP P G SG EP +G A PG + G G G+ Sbjct: 416 GPSGPQGPG-GPPGPKGNSG--------EPGAPGSKGDTGAKGEPGPVGVQGPPGPAGEE 466 Query: 713 QSPGA-----GVGLPSAASERRPPPPDFATSALG--------GQPGFPFGAAGRQSTPHS 759 GA GLP ER P A G G+ G P G AG + +P Sbjct: 467 GKRGARGEPGPTGLPGPPGERGGPGSRGFPGADGVAGPKGPAGERGSP-GPAGPKGSPGE 525 Query: 760 G--PGVNSPPSAGGGGGSSGG-GGGGGAYPPQP---DFQPSQRTSASKLGALSLGSFNKP 813 PG P A G GS G G G PP P D +P G + F P Sbjct: 526 AGRPGEAGLPGAKGLTGSPGSPGPDGKTGPPGPAGQDGRPGPPGPPGARGQAGVMGFPGP 585 Query: 814 SSKDNLFGQSCLAALSTACQNMIASLGAPNLNVTFNKKNPPEGKRKLSQNETDGAAVAGN 873 G+ A ++G + + PP + G AG+ Sbjct: 586 KGAAGEPGK----AGERGVPGPPGAVGPAGKDGEAGAQGPPGPAGPAGERGEQGP--AGS 639 Query: 874 PGSDYFPGGTAP----------------GAPGPGGPSGTSSSGSK--ASGPPNPPAQGDG 915 PG PG P GAPGP G G + GPP P Sbjct: 640 PGFQGLPGPAGPPGEAGKPGEQGVPGDLGAPGPSGARGERGFPGERGVQGPPGPAGPRGA 699 Query: 916 TSLSPNYTLESTSGNDGKPVSGGGGRGRGRRKRDSGHVSPGTFFDKYSAAPDSGGAPGVS 975 N + +G G P S G +G PG D+ A P GA G S Sbjct: 700 NGAPGNDGAKGDAGAPGAPGSQGAPGLQGMPGERGAAGLPGPKGDRGDAGPK--GADG-S 756 Query: 976 PGQQQASGAAVGGSSAGETRGAPTPHEKALTSPSWGKGAELLLGDQPDLIGSLDGGAKSD 1035 PG+ G G A P +K + PS G G G + + Sbjct: 757 PGKDGVRGLT---GPIGPPGPAGAPGDKGESGPSGPAGPTGARGAP---------GDRGE 804 Query: 1036 SSSPNVGEFASDEVSTSYANEDEVSSSSDNPQALVKASRSPLVTGSPKLPPRGVG----- 1090 P FA + + + + A K P P PP +G Sbjct: 805 PGPPGPAGFAGPP-----GADGQPGAKGEPGDAGAKGDAGPPGPAGPAGPPGPIGNVGAP 859 Query: 1091 --AGEHGPKAPPPALGLGIMSNSTSTPDSYGGGGGPGHPGTPGLEQVRTPTSSSG-APPP 1147 G G PP A G + P G G PG PG G E + P +G A P Sbjct: 860 GAKGARGSAGPPGATGFPGAAGRVGPPGPSGNAGPPGPPGPAGKEGGKGPRGETGPAGRP 919 Query: 1148 DEIHP 1152 E+ P Sbjct: 920 GEVGP 924 Score = 84.3 bits (207), Expect = 7e-16 Identities = 159/628 (25%), Positives = 213/628 (33%), Gaps = 118/628 (18%) Query: 579 GHPGDVGQGGLVHGGPVGGLAQPNFEREGGSTG-AGRLGTFEQQAPHLAQESAWFSGPHP 637 G PG+ G+ G GP+G P + G G AG+ G ++ P Q + G Sbjct: 203 GPPGEPGEPGA--SGPMGPRGPPGPPGKNGDDGEAGKPGRPGERGPPGPQGARGLPGTAG 260 Query: 638 PPGDLLPRRMGG-SGLPADCGPHDPSLAPPPPPGGSGVLFRGPLQEPMRMPGEGHVPALP 696 PG R G G D GP P P PG +G + P +PGE P P Sbjct: 261 LPGMKGHRGFSGLDGAKGDAGPAGPK-GEPGSPGENGAPGQ---MGPRGLPGERGRPGAP 316 Query: 697 SPGLQFG--GSLGGLGQL--QSPGAGVGLPSAASERRPPPPDFATSALG-----GQPG-- 745 P G G+ G G P G P A + P + G G+PG Sbjct: 317 GPAGARGNDGATGAAGPPGPTGPAGPPGFPGAVGAKGEAGPQGPRGSEGPQGVRGEPGPP 376 Query: 746 FPFGAAGRQSTPHSGPGVNSPPSAGGGGGSSGGGGGGG-------AYPPQPDFQPSQRTS 798 P GAAG P PG + P A G G+ G G G + P P P + + Sbjct: 377 GPAGAAG----PAGNPGADGQPGAKGANGAPGIAGAPGFPGARGPSGPQGPGGPPGPKGN 432 Query: 799 ASKLGALSLGSFNKPSSKDNLFGQSCLAALSTACQNMIASLGAPNLNVTFNKKNPP---- 854 + + GA P SK + GA + PP Sbjct: 433 SGEPGA--------PGSKGDT--------------------GAKGEPGPVGVQGPPGPAG 464 Query: 855 -EGKRKLSQNETDGAAVAG------NPGSDYFPGGTAPGAPGPGGPSGTSSSGSKASGPP 907 EGKR ++ E + G PGS FPG A G GP GP+G S A GP Sbjct: 465 EEGKRG-ARGEPGPTGLPGPPGERGGPGSRGFPG--ADGVAGPKGPAGERGSPGPA-GPK 520 Query: 908 NPPAQGDGTSLSPNYTLESTSGNDGKPVSGGGGRGRGRRKRDSGHVSPGTFFDKYSAAPD 967 P + + + +G+ G P G G +D PG P Sbjct: 521 GSPGEAGRPGEAGLPGAKGLTGSPGSPGPDGKTGPPGPAGQDGRPGPPGP--------PG 572 Query: 968 SGGAPGVSPGQQQASGAAVGGSSAGETRGAPTPHEKALTSPSWGKGAELLLGDQPDLIGS 1027 + G GV G GAA AGE RG P P P+ GK E P G Sbjct: 573 ARGQAGVM-GFPGPKGAAGEPGKAGE-RGVPGP--PGAVGPA-GKDGEAGAQGPPGPAGP 627 Query: 1028 L-DGGAKSDSSSPNVGEFASDEVSTSYANEDEVSSSSDNPQALVKASRSPLVTGSPKLPP 1086 + G + + SP A + Q + +P +G+ Sbjct: 628 AGERGEQGPAGSPGFQGLPGPAGPPGEAGKP-------GEQGVPGDLGAPGPSGARG--E 678 Query: 1087 RGVGAGEHGPKAPPPALGLGIMSNSTSTPDSYGGGGGPGHPGT---PGLEQV-------- 1135 RG GE G + PP G + + + G G PG PG+ PGL+ + Sbjct: 679 RGF-PGERGVQGPPGPAGPRGANGAPGNDGAKGDAGAPGAPGSQGAPGLQGMPGERGAAG 737 Query: 1136 ----------RTPTSSSGAPPPDEIHPL 1153 P + G+P D + L Sbjct: 738 LPGPKGDRGDAGPKGADGSPGKDGVRGL 765 Score = 56.2 bits (134), Expect = 2e-07 Identities = 89/335 (26%), Positives = 112/335 (33%), Gaps = 64/335 (19%) Query: 854 PEGKRKLSQNETDGA-------------AVAGNPGSDYFPGGTAPGAPGPGGPSGTSSSG 900 P+G + ET G AG PG D PG PG PGP GP G Sbjct: 96 PDGSESPTDQETTGVEGPKGDTGPRGPRGPAGPPGRDGIPG--QPGLPGPPGPPG----- 148 Query: 901 SKASGPPNPPAQGDGTS--LSPNYTLESTSGNDGKPVSGGGGRG-RGRRKRDSGHVSPGT 957 PP PP G + LS Y +ST G +S G G G R +PG Sbjct: 149 -----PPGPPGLGGNFAPQLSYGYDEKSTGG-----ISVPGPMGPSGPRGLPGPPGAPGP 198 Query: 958 FFDKYSAAPDSGGAPGVSP--GQQQASGAAVGGSSAGETRGAPTPHEKALTSPSWGKGAE 1015 + P G PG S G + G GE P E+ P +G Sbjct: 199 --QGFQGPPGEPGEPGASGPMGPRGPPGPPGKNGDDGEAGKPGRPGERGPPGPQGARGLP 256 Query: 1016 LLLGDQPDLIG-----SLDG--------GAKSDSSSPNVGEFASDEVSTSYANEDEVSSS 1062 G P + G LDG G K + SP A ++ + Sbjct: 257 GTAG-LPGMKGHRGFSGLDGAKGDAGPAGPKGEPGSPGENG-APGQMGPRGLPGERGRPG 314 Query: 1063 SDNP------QALVKASRSPLVTGSPKLP--PRGVGA-GEHGPKAPPPALGLGIMSNSTS 1113 + P A+ P TG P P VGA GE GP+ P + G + Sbjct: 315 APGPAGARGNDGATGAAGPPGPTGPAGPPGFPGAVGAKGEAGPQGPRGSEGPQGVRGEPG 374 Query: 1114 TPDSYGGGGGPGHPGT---PGLEQVRTPTSSSGAP 1145 P G G G+PG PG + +GAP Sbjct: 375 PPGPAGAAGPAGNPGADGQPGAKGANGAPGIAGAP 409 >gi|21264565 AT rich interactive domain 1A isoform a [Homo sapiens] Length = 2285 Score = 103 bits (256), Expect = 1e-21 Identities = 288/1239 (23%), Positives = 401/1239 (32%), Gaps = 273/1239 (22%) Query: 8 EPQVNSRNAGQGERNFNETGLSMNTHFKAPAFHTGGPPG-----PVDPAMSALGEPPILG 62 EP + + N G R ++N + P GG P A +AL PP G Sbjct: 97 EPDLKNSNGNAGPRP------ALNNNLTEPPGGGGGGSSDGVGAPPHSAAAAL-PPPAYG 149 Query: 63 MNMEPYG-------------FHARGHSELHAGGLQAQPVHGFFGGQQPHHGHPGSHHPH- 108 +PYG FH + H + GL A G GG +P+ G + H H Sbjct: 150 FG-QPYGRSPSAVAAAAAAVFHQQ-HGGQQSPGLAALQSGGG-GGLEPYAGPQQNSHDHG 206 Query: 109 ----QHHPHFGGNFGGPDPGASCLHGGRLLGY--GGAAGGLGSQPPFAEGYEHMAESQGP 162 Q++ ++ P P + G GAA GS+PP + + S Sbjct: 207 FPNHQYNSYYPNRSAYPPPAPAYALSSPRGGTPGSGAAAAAGSKPPPSSS---ASASSSS 263 Query: 163 ESFGPQRPGNLPDFHSSGASSHAVPAPCLP----LDQSPNRAASFHGLPSSSGSDSHSLE 218 SF QR G + S A P L SP+ A + G P S Sbjct: 264 SSFAQQRFGAMGGGGPSAAGGGTPQPTATPTLNQLLTSPSSARGYQGYPGGDYSG----- 318 Query: 219 PRRVTNQGAVDSLEYNYPGEAPSGHFDMFSPSDSEGQLPHYAAGRQVPGGAFPGASAMPR 278 G D G A G DM S G AA GGA + P Sbjct: 319 -------GPQD-------GGAGKGPADM--ASQCWGAAAAAAAAAAASGGAQQRSHHAPM 362 Query: 279 AAGMVGLSKMHAQPPQQQPQQQQQPQQQQQQHGVFFERFSGARKMPVGLEPSVGSRHPLM 338 + G G QP + PQ Q +G P Sbjct: 363 SPGSSGGG---GQPLARTPQPSSPMDQ-------------------------MGKMRP-- 392 Query: 339 QPPQQAPPPPQQQPPQQPPQQ---QPPPPPGLLVRQNSCPPALPRPQQGEAGTPSGGLQ- 394 QP P QQQ P PQQ P P G + P P QG A + GGL Sbjct: 393 QPYGGTNPYSQQQGPPSGPQQGHGYPGQPYG-----SQTPQRYPMTMQGRAQSAMGGLSY 447 Query: 395 --------DGGPMLPSQHAQFEYPIHRLENRSMHPYSE-PVFSMQHPPPQQAPNQRLQHF 445 GP Q Q Y +S HP + P +S Q PP Q P+ + Sbjct: 448 TQQIPPYGQQGPSGYGQQGQTPY----YNQQSPHPQQQQPPYSQQ--PPSQTPHAQ---- 497 Query: 446 DAPPYMNVAKRPRFDFPGSAGVDRCASWNGSMHNGALDNHLSPSAYPGLPGEFTPPVPDS 505 P Y P + P PP Sbjct: 498 --PSYQQ----------------------------------QPQSQPPQLQSSQPPYSQQ 521 Query: 506 FPSGPPLQHPAPDHQSLQQQQQQQQQQQQQQQQQQQQQQQQQQQQRQNAALMIKQMAS-- 563 PS PP Q + S Q QQ Q Q Q Q Q QQQQ +Q A + Q A+ Sbjct: 522 -PSQPPHQQSPAPYPSQQSTTQQHPQSQPPYSQPQAQSPYQQQQPQQPAPSTLSQQAAYP 580 Query: 564 RNQQQRLRQPNLAQLGHPGDVGQGGLVHGGPVGGLAQPNFEREGGSTGAGRLGTFEQQAP 623 + Q Q+ +Q +Q P P L+Q +F + S + Q+ Sbjct: 581 QPQSQQSQQTAYSQQRFP------------PPQELSQDSFGSQASSAPSMTSSKGGQEDM 628 Query: 624 HLAQESAWFSGPHPPPG-DLLPRRMGG--------SGLPADCG---------------PH 659 +L+ +S S P D LP G SG+ + G PH Sbjct: 629 NLSLQSRPSSLPDLSGSIDDLPMGTEGALSPGVSTSGISSSQGEQSNPAQSPFSPHTSPH 688 Query: 660 DPSL-APPPPPGGSGVLF----RGPLQEPMRMPGEGHVPALPSPGLQFGGSLGGLGQLQS 714 P + P P P GS GPL P +PG P PS G + Sbjct: 689 LPGIRGPSPSPVGSPASVAQSRSGPL-SPAAVPGNQMPPRPPS------GQSDSIMHPSM 741 Query: 715 PGAGVGLPSAASERRPPPPDFATSALGGQPG---FPFGAAGRQSTPHSGPGVNSPPSAGG 771 + + +R P P +++ QPG P +G Q H+G G S G Sbjct: 742 NQSSIAQDRGYMQRNPQMPQYSSP----QPGSALSPRQPSGGQI--HTGMGSYQQNSMGS 795 Query: 772 GGGSSGGGGGGGAYPPQPDFQPSQRTSASKLGALSLGSFNKPSSKDNLFGQSCLAALSTA 831 G G G G YP QP++ + G G N + + GQ + T Sbjct: 796 YGPQGGQYGPQGGYPRQPNYNALPNANYPSAG--MAGGINPMGAGGQMHGQPGIPPYGTL 853 Query: 832 CQNMI--ASLG----APNL-----NVTFNKKNPPEGKRKLSQNETDGAAVAGN------P 874 + AS+G PN+ V PP G + +Q VA N P Sbjct: 854 PPGRMSHASMGNRPYGPNMANMPPQVGSGMCPPPGGMNRKTQETAVAMHVAANSIQNRPP 913 Query: 875 GSDYFPGGTAPGAPGPGGPSGTS-SSGSKASGPPNPPAQGDGTSLSPNYTLESTSGNDG- 932 G +P G G G P G +S + P PP GT + + + ++ G Sbjct: 914 G---YPNMNQGGMMGTGPPYGQGINSMAGMINPQGPPYSMGGTMANNSAGMAASPEMMGL 970 Query: 933 -----KPVSGGGGRGRGRRKRDS---GHVSPGTFFDKYSAAPDSGGAP----GVSPGQQQ 980 P + + G K +S S T +K + + GG P V Sbjct: 971 GDVKLTPATKMNNKADGTPKTESKSKKSSSSTTTNEKITKLYELGGEPERKMWVDRYLAF 1030 Query: 981 ASGAAVGGSSAGETRGAPTPHEKALTSPSWGKGAELLLGDQP--DLIGSLDGGAKSDSSS 1038 A+G ++ P + S G + ++ +L +L+ G S ++S Sbjct: 1031 TEEKAMGMTNLPAVGRKPLDLYRLYVSVKEIGGLTQVNKNKKWRELATNLNVGTSSSAAS 1090 Query: 1039 PNVGEFASDEVSTSYANEDEVSSSSDNPQALVKASRSPLVTGSPKL-PPRGVGAGE-HGP 1096 + YA E ++ D P + A+ S PK+ PP G+G GP Sbjct: 1091 ----SLKKQYIQCLYAFECKIERGEDPPPDIFAAADSK--KSQPKIQPPSPAGSGSMQGP 1144 Query: 1097 KAPPPALGLGIMSNSTSTPDSYGGGGGPGHPGTPGLEQV 1135 + P STS+ + GG P P + Q+ Sbjct: 1145 QTP----------QSTSSSMAEGGDLKPPTPASTPHSQI 1173 Score = 84.3 bits (207), Expect = 7e-16 Identities = 266/1237 (21%), Positives = 393/1237 (31%), Gaps = 268/1237 (21%) Query: 3 GLDQFE-PQVNSRNAGQGERNFNETGLSMNTHFK-APAFHTGGPPG--PVDPAMSALGEP 58 GL+ + PQ NS + G +N + + + APA+ P G P A +A G Sbjct: 191 GLEPYAGPQQNSHDHGFPNHQYNSYYPNRSAYPPPAPAYALSSPRGGTPGSGAAAAAGSK 250 Query: 59 PILGMNMEPYGFHARGHSELHAGGLQAQPVHGFFGGQQPHHGHPGSHHP----------- 107 P P A S + AQ G GG P G+ P Sbjct: 251 P-------PPSSSASASS---SSSSFAQQRFGAMGGGGPSAAGGGTPQPTATPTLNQLLT 300 Query: 108 -------HQHHPHFGGNF-GGPDPGASCLHGGRLLGYGGAAGGLGSQPPFAEGYEHMAES 159 +Q +P GG++ GGP G + + A + A G Sbjct: 301 SPSSARGYQGYP--GGDYSGGPQDGGAGKGPADMASQCWGAAAAAAAAAAASGGAQQRSH 358 Query: 160 QGPESFGPQRPGNLPDFHSSGASSHAVPAPCLPLDQSPNRAASFHGLPSSSGSDSHSLE- 218 P S G G P + P P P+DQ +G G++ +S + Sbjct: 359 HAPMSPGSSGGGGQPLART--------PQPSSPMDQMGKMRPQPYG-----GTNPYSQQQ 405 Query: 219 -PRRVTNQGAVDSLEYNYPGEAPSGHFDMFSPSDSEGQLPHYAAG----RQVPGGAFPGA 273 P QG + YPG+ P +G+ G +Q+P G Sbjct: 406 GPPSGPQQG------HGYPGQPYGSQTPQRYPMTMQGRAQSAMGGLSYTQQIPPYGQQGP 459 Query: 274 SAMPRAAGMVGLSKMHAQPPQQQPQQQQQPQQQQQQHGVFFERFSGARKMPVGLEPSVGS 333 S + ++ P QQQP QQP Q +PS Sbjct: 460 SGYGQQGQTPYYNQQSPHPQQQQPPYSQQPPSQTPH-----------------AQPSY-Q 501 Query: 334 RHPLMQPPQ-QAPPPPQQQPPQQPPQQQPPPP-PGLLVRQNSCPPALPRPQQGEAGTPSG 391 + P QPPQ Q+ PP Q P QPP QQ P P P P + P Q +A +P Sbjct: 502 QQPQSQPPQLQSSQPPYSQQPSQPPHQQSPAPYPSQQSTTQQHPQSQPPYSQPQAQSPYQ 561 Query: 392 GLQDGGPMLPSQHAQFEYPIHRLENRSMHPYSEPVFSMQHPPPQQAPNQRLQHFDAPPYM 451 Q P + Q YP + + YS+ F PP + + + + P M Sbjct: 562 QQQPQQPAPSTLSQQAAYPQPQSQQSQQTAYSQQRFP---PPQELSQDSFGSQASSAPSM 618 Query: 452 NVAK------------RPRF--DFPGS---------------AGVDRCASWNGSMHNGAL 482 +K RP D GS +S G N A Sbjct: 619 TSSKGGQEDMNLSLQSRPSSLPDLSGSIDDLPMGTEGALSPGVSTSGISSSQGEQSNPA- 677 Query: 483 DNHLSPSAYPGLPGEFTP-PVP----------------------DSFPSGPP------LQ 513 + SP P LPG P P P + P PP + Sbjct: 678 QSPFSPHTSPHLPGIRGPSPSPVGSPASVAQSRSGPLSPAAVPGNQMPPRPPSGQSDSIM 737 Query: 514 HPAPDHQSLQQQQQQQQQQQQQQQQQQQQQQQQQQQQRQNAALMIKQMASRNQQQR---- 569 HP+ + S+ Q + Q+ Q Q Q ++ + + M S Q Sbjct: 738 HPSMNQSSIAQDRGYMQRNPQMPQYSSPQPGSALSPRQPSGGQIHTGMGSYQQNSMGSYG 797 Query: 570 ------------LRQPNLAQL-----------GHPGDVGQGGLVHGGPVGGLAQPNFERE 606 RQPN L G +G GG +HG P G+ P Sbjct: 798 PQGGQYGPQGGYPRQPNYNALPNANYPSAGMAGGINPMGAGGQMHGQP--GIP-PYGTLP 854 Query: 607 GGSTGAGRLGTFEQQAPHLAQESAWF-SGPHPPPGDLLPRRMGGSGLPADCGPHDPSLAP 665 G +G P++A SG PPPG + R+ + + + P Sbjct: 855 PGRMSHASMGN-RPYGPNMANMPPQVGSGMCPPPGGM-NRKTQETAVAMHVAANSIQNRP 912 Query: 666 PP-------------PPGGSGVLFRGPLQEPMRMP-GEGHVPALPSPGLQFGGSLGGLGQ 711 P PP G G+ + P P G A S G+ + GLG Sbjct: 913 PGYPNMNQGGMMGTGPPYGQGINSMAGMINPQGPPYSMGGTMANNSAGMAASPEMMGLGD 972 Query: 712 LQSPGA------GVGLPSAASERRPPPPDFATSA-------LGGQPGFPFGAAGRQS-TP 757 ++ A G P S+ + T+ LGG+P + T Sbjct: 973 VKLTPATKMNNKADGTPKTESKSKKSSSSTTTNEKITKLYELGGEPERKMWVDRYLAFTE 1032 Query: 758 HSGPGVNSPPSAGGGGGSSGGGGGGGAYPPQPDFQPSQRTSASKLGALSLGSFNKPSSK- 816 G+ + P+ G +P S ++G L+ + NK + Sbjct: 1033 EKAMGMTNLPAVGR----------------KPLDLYRLYVSVKEIGGLTQVNKNKKWREL 1076 Query: 817 -DNLFGQSCLAALSTACQNMIASLGAPNLNVTFNKKNPPE----GKRKLSQNETDGAAVA 871 NL + +A S+ + I L A + + PP+ K SQ + + A Sbjct: 1077 ATNLNVGTSSSAASSLKKQYIQCLYAFECKIERGEDPPPDIFAAADSKKSQPKIQPPSPA 1136 Query: 872 GNPGSDYFPGGTAPGAPGPGGPSGTSSSGSKASGPPNPPAQGDGTSLSPNYTLESTSGND 931 G+ GP P TSSS ++ P S P S S + Sbjct: 1137 GSGSMQ-----------GPQTPQSTSSSMAEGGDLKPPTPASTPHSQIPPLPGMSRSNSV 1185 Query: 932 GKPVSGGGGRGRGRRKRDSGHVSPG--------TFFDKYSAAPDS----------GGAPG 973 G + G +KR+S +PG + S P+ G P Sbjct: 1186 GIQDAFNDGSDSTFQKRNSMTPNPGYQPSMNTSDMMGRMSYEPNKDPYGSMRKAPGSDPF 1245 Query: 974 VSPGQ----------QQASGAAVGGSSAGETRGAP--TPHEKALTSPSWGKGAELLLG-D 1020 +S GQ +A+G +G + G + P P+++ T P G + G Sbjct: 1246 MSSGQGPNGGMGDPYSRAAGPGLGNVAMGPRQHYPYGGPYDRVRTEPGIGPEGNMSTGAP 1305 Query: 1021 QPDLIGS-LDGGAKSDSSSPNVGEFASDEVSTSYANE 1056 QP+L+ S D G S S P + + SY N+ Sbjct: 1306 QPNLMPSNPDSGMYSPSRYPPQQQQQQQQRHDSYGNQ 1342 Score = 60.1 bits (144), Expect = 1e-08 Identities = 130/561 (23%), Positives = 180/561 (32%), Gaps = 112/561 (19%) Query: 661 PSLAPPPPPG------------------GSGVLFRGPLQEPMRMPGEGHVPALPSPGLQF 702 P++ PP P G GSG GP EP G+ P+ Sbjct: 61 PAVGPPQPLGKELQDGAESNGGGGGGGAGSG---GGPGAEPDLKNSNGNAGPRPALNNNL 117 Query: 703 GGSLGGLGQLQSPGAGVGLPSAASERRPPPPDFATSALGGQPGFPFGAAG----RQSTPH 758 GG G S G G SAA+ PP F G P AA +Q Sbjct: 118 TEPPGGGGGGSSDGVGAPPHSAAAALPPPAYGFG-QPYGRSPSAVAAAAAAVFHQQHGGQ 176 Query: 759 SGPGVNSPPSAGGGGGSSGGG-------------------GGGGAYPPQPDFQPSQRTSA 799 PG+ + S GGGG G AYPP P+ S+ Sbjct: 177 QSPGLAALQSGGGGGLEPYAGPQQNSHDHGFPNHQYNSYYPNRSAYPPP---APAYALSS 233 Query: 800 SKLG------ALSLGSFNKPSSKDNLFGQSCLAALSTACQNMIASLGAPNLNVTFNKKNP 853 + G A + GS PSS S ++ S+ Q ++G + Sbjct: 234 PRGGTPGSGAAAAAGSKPPPSS-----SASASSSSSSFAQQRFGAMGGGGPSAAGGGTPQ 288 Query: 854 PEGKRKLSQNETDGAAVAGNPGSDYFPGGTAPGAPGPG----GPSGTSSSGSKASGPPNP 909 P L+Q T ++ G G +PGG G P G GP+ +S A+ Sbjct: 289 PTATPTLNQLLTSPSSARGYQG---YPGGDYSGGPQDGGAGKGPADMASQCWGAAAAAAA 345 Query: 910 PAQGDGTSLSPNYTLESTSGNDGKPVSGGGGRGRGRRKRDSGHVSPGTFFDKYSAAPDSG 969 A G + ++ + G+ SGGGG+ R + S SP K P G Sbjct: 346 AAAASGGAQQRSHHAPMSPGS-----SGGGGQPLARTPQPS---SPMDQMGKMRPQP-YG 396 Query: 970 GAPGVSPGQQQASGAAVGGSSAGETRGAPTPHEKALTSPSWGKGAELLLGDQPDLIGSLD 1029 G S Q SG G G+ G+ TP +T + A Sbjct: 397 GTNPYSQQQGPPSGPQQGHGYPGQPYGSQTPQRYPMTMQGRAQSAM-------------- 442 Query: 1030 GGAKSDSSSPNVGEFA----SDEVSTSYANEDEVSSSSDNPQALVKASRSPLVTGSPKLP 1085 GG P G+ + T Y N+ S +PQ + P P Sbjct: 443 GGLSYTQQIPPYGQQGPSGYGQQGQTPYYNQ-----QSPHPQ----QQQPPYSQQPPSQT 493 Query: 1086 PRGVGAGEHGPKAPPPALGLGIMSNSTSTPDSYGGGGGPGHPGTPGLEQVRTPTSSSGAP 1145 P + + P++ PP L +S P P H +P + T+ Sbjct: 494 PHAQPSYQQQPQSQPPQL-------QSSQPPYSQQPSQPPHQQSPAPYPSQQSTTQQ--- 543 Query: 1146 PPDEIHPLEILQAQIQLQRQQ 1166 P P QAQ Q+QQ Sbjct: 544 HPQSQPPYSQPQAQSPYQQQQ 564 Score = 57.4 bits (137), Expect = 9e-08 Identities = 107/440 (24%), Positives = 143/440 (32%), Gaps = 72/440 (16%) Query: 721 LPSAASERRPPPPDFATSALGGQPGFPFGAAGRQSTPHSGPGVNSPP------------S 768 L A ++R A +A + G AAG++S GP V P + Sbjct: 24 LKKAEQQQREEAGGEAAAAAAAERGEMKAAAGQES---EGPAVGPPQPLGKELQDGAESN 80 Query: 769 AGGGGGSSGGGGGGGAYPPQPDFQPSQRTSASKLGALSLGSFNKPSSKDNLFGQSCLAAL 828 GGGGG +G GGG GA +PD + S +A AL+ P G + Sbjct: 81 GGGGGGGAGSGGGPGA---EPDLKNS-NGNAGPRPALNNNLTEPPGGG----GGGSSDGV 132 Query: 829 STACQNMIASLGAPNLNVTFNKKNPPEGKRKLSQNETDGAAVAGNPGSDYFPGGTAPGAP 888 + A+L P P G+ + A G PG A + Sbjct: 133 GAPPHSAAAALPPPAYGF-----GQPYGRSPSAVAAAAAAVFHQQHGGQQSPGLAALQSG 187 Query: 889 GPGG--PSGTSSSGSKASGPPNP------PAQGDGTSLSPNYTLESTSGNDGKPVSGGGG 940 G GG P S G PN P + +P Y L S G G P SG Sbjct: 188 GGGGLEPYAGPQQNSHDHGFPNHQYNSYYPNRSAYPPPAPAYALSSPRG--GTPGSGAAA 245 Query: 941 RGRGRRKRDSGHVSPGTFFDKYSAAPDSGGAPGVSPGQQQASGAAVGGSSAGETRGAPTP 1000 + S SA+ S S QQ GA GG + G P P Sbjct: 246 AAGSKPPPSS------------SASASSSS----SSFAQQRFGAMGGGGPSAAGGGTPQP 289 Query: 1001 H-----EKALTSPSWGKGAELLLGDQPDLIGSLDGGAKSDSSSPNVGEFASDEVSTSYAN 1055 + LTSPS +G + G G GG + + + AS + A Sbjct: 290 TATPTLNQLLTSPSSARGYQGYPG------GDYSGGPQDGGAGKGPADMASQCWGAAAAA 343 Query: 1056 EDEVSSSSDNPQALVKASRSPLVTGS-----PKLPPRGVGAGEHGPKAPPPALGLGIMSN 1110 ++S Q A SP +G + P + G P P G S Sbjct: 344 AAAAAASGGAQQRSHHAPMSPGSSGGGGQPLARTPQPSSPMDQMGKMRPQPYGGTNPYSQ 403 Query: 1111 STSTPDSYGGGGGPGHPGTP 1130 P G G G+PG P Sbjct: 404 QQGPPS--GPQQGHGYPGQP 421 Score = 52.4 bits (124), Expect = 3e-06 Identities = 85/329 (25%), Positives = 116/329 (35%), Gaps = 82/329 (24%) Query: 853 PPEGKRKLSQNETDGAAVAGNPGSDYFPGGTAPGAPGPGGPSGTSSSGSKASGPPNPPAQ 912 PP +K Q + + A GG A A +++G ++ GP P Q Sbjct: 20 PPSELKKAEQQQREEA------------GGEAAAAAAAERGEMKAAAGQESEGPAVGPPQ 67 Query: 913 GDGTSLSPNYTLESTSGNDGKPVSGGGGRGRGRRKRDSGHVSPGTFFDKYSAAPDSGGAP 972 G L ES G G GG G G G PG D ++ ++G P Sbjct: 68 PLGKELQDG--AESNGGGGG----GGAGSGGG----------PGAEPDLKNSNGNAGPRP 111 Query: 973 GVSPGQQQASGAAVGGSSAGETRGAPTPHEKALTSPSWGKGAELLLGDQPDLI------- 1025 ++ + G GGSS G GAP PH A P G G P + Sbjct: 112 ALNNNLTEPPGGGGGGSSDGV--GAP-PHSAAAALPPPAYGFGQPYGRSPSAVAAAAAAV 168 Query: 1026 ---------------------GSLDGGAKSDSSSPNVGEFASDEVSTSYANEDEVSSSSD 1064 G L+ A +S + G F + + ++ Y N S+ Sbjct: 169 FHQQHGGQQSPGLAALQSGGGGGLEPYAGPQQNSHDHG-FPNHQYNSYYPNR-----SAY 222 Query: 1065 NPQALVKASRSPLVTGSPKLPPRGVGAGEHGPKAPPPALGLGIMSNSTS-TPDSYG--GG 1121 P A A SP G+P G GA PPP+ S+S+S +G GG Sbjct: 223 PPPAPAYALSSPR-GGTP-----GSGAAAAAGSKPPPSSSASASSSSSSFAQQRFGAMGG 276 Query: 1122 GGPGHPG--------TPGLEQVRTPTSSS 1142 GGP G TP L Q+ T SS+ Sbjct: 277 GGPSAAGGGTPQPTATPTLNQLLTSPSSA 305 Score = 47.0 bits (110), Expect = 1e-04 Identities = 95/418 (22%), Positives = 135/418 (32%), Gaps = 88/418 (21%) Query: 135 GYGGAAGGLGSQPPFAEGYEHMAESQG--PE---SFGPQRPGNLPDFHSSGASSHAVPAP 189 G G A G P+ Y+ + G PE S G +P +P SG S + P Sbjct: 1267 GLGNVAMGPRQHYPYGGPYDRVRTEPGIGPEGNMSTGAPQPNLMPSNPDSGMYSPSRYPP 1326 Query: 190 CLPLDQSPNRAASFHGLPSSSGSDSHSLEPRRVTNQGAVDSLEYNYPGEAPSGHFDMFSP 249 Q R S+ S+ G+ S S P + T Y P + G Sbjct: 1327 -QQQQQQQQRHDSYGNQFSTQGTPSGSPFPSQQTTMYQQQQQNYKRPMDGTYGP----PA 1381 Query: 250 SDSEGQLPHYAAGRQVPGGAFPGASAMPRAAGMVGLSKMHAQPPQQQPQQQQQPQQQQQQ 309 EG++ ++P + G + P Q QP QQQ Q Q Sbjct: 1382 KRHEGEM-----------------YSVPYSTGQGQPQQQQLPPAQPQPASQQQAAQPSPQ 1424 Query: 310 HGVFFERFSGARKMPVGLEPSVGSRHPLMQPPQQAPPP---PQQQPPQQPPQQQPPPPPG 366 V+ + G+ +P P PQ Q P Q + + PPG Sbjct: 1425 QDVYNQ---------------YGNAYPATATAATERRPAGGPQNQFPFQFGRDRVSAPPG 1469 Query: 367 LLVRQNSCPPALPRPQQGEA-----GTPSGGLQD------------GGPMLPSQHA--QF 407 +QN P + P Q A GT G D P P+ H + Sbjct: 1470 TNAQQNMPPQMMGGPIQASAEVAQQGTMWQGRNDMTYNYANRQSTGSAPQGPAYHGVNRT 1529 Query: 408 EYPIHRLENRSMHPYSEPVFSMQHPPPQQAPNQRLQHFDAPPYMNVAKRPRF-----DFP 462 + +H + R+ H S P + PP P+ + PP N P Sbjct: 1530 DEMLH-TDQRANHEGSWPSHGTRQPP--YGPSAPVPPMTRPPPSNYQPPPSMQNHIPQVS 1586 Query: 463 GSAGVDRCASWNGSMHNGALDNHLSPSAYPGLPG-----EFTPPVPDSFPSGPPLQHP 515 A + R ++N SPS P L + PPVP S + P+Q P Sbjct: 1587 SPAPLPR-----------PMENRTSPSKSPFLHSGMKMQKAGPPVPASHIAPAPVQPP 1633 Score = 44.3 bits (103), Expect = 8e-04 Identities = 75/300 (25%), Positives = 97/300 (32%), Gaps = 61/300 (20%) Query: 336 PLMQPPQQAPPPPQQQPPQQPPQQQP----------PPPPGLLVRQNSCPPALPRPQQGE 385 P +QPP A Q P Q PQ PP P S P + P G Sbjct: 1128 PKIQPPSPAGSGSMQGP--QTPQSTSSSMAEGGDLKPPTPA------STPHSQIPPLPGM 1179 Query: 386 AGTPSGGLQDG------------GPMLPSQHAQFEYPIHRLENR-SMHPYSEPVFSMQHP 432 + + S G+QD M P+ Q + R S P +P SM+ Sbjct: 1180 SRSNSVGIQDAFNDGSDSTFQKRNSMTPNPGYQPSMNTSDMMGRMSYEPNKDPYGSMRKA 1239 Query: 433 PPQ-------QAPNQRL----QHFDAPPYMNVAKRPRFDFPGSAGVDRCASWNGSMHNGA 481 P Q PN + P NVA PR +P DR + G G Sbjct: 1240 PGSDPFMSSGQGPNGGMGDPYSRAAGPGLGNVAMGPRQHYPYGGPYDRVRTEPGIGPEG- 1298 Query: 482 LDNHLSPSAYPGLPGEFTPPVPDSFPSGPPLQHPAPDHQSLQQQQQQQQQQQQQQQQQQQ 541 ++S A P P+ PS P +P QQQQQQQQ+ Q Sbjct: 1299 ---NMSTGA----------PQPNLMPSNPDSGMYSPSRYPPQQQQQQQQRHDSYGNQFST 1345 Query: 542 QQQQQQQQQRQNAALMIKQMASRNQQQRLRQPNLAQLGHPGDVGQGGLVHGGPVGGLAQP 601 Q M +Q QQQ ++P G P +G + G QP Sbjct: 1346 QGTPSGSPFPSQQTTMYQQ-----QQQNYKRPMDGTYGPPAKRHEGEMYSVPYSTGQGQP 1400 Score = 32.3 bits (72), Expect = 3.1 Identities = 75/345 (21%), Positives = 107/345 (31%), Gaps = 78/345 (22%) Query: 245 DMFSPSDSEGQLPHYAAGRQVPGGAFPGASA-MPRAAGMVGLSKMHAQPPQQQPQQQQQP 303 D+F+ +DS+ P G+ G ++ M + P P Q P Sbjct: 1116 DIFAAADSKKSQPKIQPPSPAGSGSMQGPQTPQSTSSSMAEGGDLKPPTPASTPHSQIPP 1175 Query: 304 QQQQQQHGVFFERFSGARKMPVGLEPSVGS-RHPLMQPPQQAPPPPQQQPPQQPPQQ--- 359 +R VG++ + Q P P QP Sbjct: 1176 LPGM------------SRSNSVGIQDAFNDGSDSTFQKRNSMTPNPGYQPSMNTSDMMGR 1223 Query: 360 ---QPPPPPGLLVRQNSCPPALPRPQQGEAGTPSGGLQD-----GGPML------PSQHA 405 +P P +R+ P + P G+ P+GG+ D GP L P QH Sbjct: 1224 MSYEPNKDPYGSMRK--APGSDPFMSSGQG--PNGGMGDPYSRAAGPGLGNVAMGPRQHY 1279 Query: 406 QFEYPIHRLENR----------------SMHPYSEPVFSMQHP---PPQQAPNQRLQHFD 446 + P R+ ++ P S P M P PPQQ Q+ +H Sbjct: 1280 PYGGPYDRVRTEPGIGPEGNMSTGAPQPNLMP-SNPDSGMYSPSRYPPQQQQQQQQRH-- 1336 Query: 447 APPYMNVAKRPRFDFPGSAGVDRCASWNGSMHNGALDNHLSPSAYPGLPGEFTPP----- 501 Y N +F G+ S +M+ N+ P + G + PP Sbjct: 1337 -DSYGN-----QFSTQGTPSGSPFPSQQTTMYQQQQQNYKRP-----MDGTYGPPAKRHE 1385 Query: 502 -----VPDSFPSGPPLQHPAPDHQSLQQQQQQQQQQQQQQQQQQQ 541 VP S G P Q P Q QQQ Q QQ Q Sbjct: 1386 GEMYSVPYSTGQGQPQQQQLPPAQPQPASQQQAAQPSPQQDVYNQ 1430 Score = 32.0 bits (71), Expect = 4.0 Identities = 20/59 (33%), Positives = 26/59 (44%), Gaps = 3/59 (5%) Query: 1090 GAGEHGPKA-PPPALGLGIMSNSTSTPDSYGGGGGPGHPGTPGLEQVRTPTSSSGAPPP 1147 G GP PP LG + + S + GGGGG G G PG E ++ + P P Sbjct: 55 GQESEGPAVGPPQPLGKELQDGAES--NGGGGGGGAGSGGGPGAEPDLKNSNGNAGPRP 111 >gi|21264575 AT rich interactive domain 1A isoform b [Homo sapiens] Length = 2068 Score = 103 bits (256), Expect = 1e-21 Identities = 288/1239 (23%), Positives = 401/1239 (32%), Gaps = 273/1239 (22%) Query: 8 EPQVNSRNAGQGERNFNETGLSMNTHFKAPAFHTGGPPG-----PVDPAMSALGEPPILG 62 EP + + N G R ++N + P GG P A +AL PP G Sbjct: 97 EPDLKNSNGNAGPRP------ALNNNLTEPPGGGGGGSSDGVGAPPHSAAAAL-PPPAYG 149 Query: 63 MNMEPYG-------------FHARGHSELHAGGLQAQPVHGFFGGQQPHHGHPGSHHPH- 108 +PYG FH + H + GL A G GG +P+ G + H H Sbjct: 150 FG-QPYGRSPSAVAAAAAAVFHQQ-HGGQQSPGLAALQSGGG-GGLEPYAGPQQNSHDHG 206 Query: 109 ----QHHPHFGGNFGGPDPGASCLHGGRLLGY--GGAAGGLGSQPPFAEGYEHMAESQGP 162 Q++ ++ P P + G GAA GS+PP + + S Sbjct: 207 FPNHQYNSYYPNRSAYPPPAPAYALSSPRGGTPGSGAAAAAGSKPPPSSS---ASASSSS 263 Query: 163 ESFGPQRPGNLPDFHSSGASSHAVPAPCLP----LDQSPNRAASFHGLPSSSGSDSHSLE 218 SF QR G + S A P L SP+ A + G P S Sbjct: 264 SSFAQQRFGAMGGGGPSAAGGGTPQPTATPTLNQLLTSPSSARGYQGYPGGDYSG----- 318 Query: 219 PRRVTNQGAVDSLEYNYPGEAPSGHFDMFSPSDSEGQLPHYAAGRQVPGGAFPGASAMPR 278 G D G A G DM S G AA GGA + P Sbjct: 319 -------GPQD-------GGAGKGPADM--ASQCWGAAAAAAAAAAASGGAQQRSHHAPM 362 Query: 279 AAGMVGLSKMHAQPPQQQPQQQQQPQQQQQQHGVFFERFSGARKMPVGLEPSVGSRHPLM 338 + G G QP + PQ Q +G P Sbjct: 363 SPGSSGGG---GQPLARTPQPSSPMDQ-------------------------MGKMRP-- 392 Query: 339 QPPQQAPPPPQQQPPQQPPQQ---QPPPPPGLLVRQNSCPPALPRPQQGEAGTPSGGLQ- 394 QP P QQQ P PQQ P P G + P P QG A + GGL Sbjct: 393 QPYGGTNPYSQQQGPPSGPQQGHGYPGQPYG-----SQTPQRYPMTMQGRAQSAMGGLSY 447 Query: 395 --------DGGPMLPSQHAQFEYPIHRLENRSMHPYSE-PVFSMQHPPPQQAPNQRLQHF 445 GP Q Q Y +S HP + P +S Q PP Q P+ + Sbjct: 448 TQQIPPYGQQGPSGYGQQGQTPY----YNQQSPHPQQQQPPYSQQ--PPSQTPHAQ---- 497 Query: 446 DAPPYMNVAKRPRFDFPGSAGVDRCASWNGSMHNGALDNHLSPSAYPGLPGEFTPPVPDS 505 P Y P + P PP Sbjct: 498 --PSYQQ----------------------------------QPQSQPPQLQSSQPPYSQQ 521 Query: 506 FPSGPPLQHPAPDHQSLQQQQQQQQQQQQQQQQQQQQQQQQQQQQRQNAALMIKQMAS-- 563 PS PP Q + S Q QQ Q Q Q Q Q QQQQ +Q A + Q A+ Sbjct: 522 -PSQPPHQQSPAPYPSQQSTTQQHPQSQPPYSQPQAQSPYQQQQPQQPAPSTLSQQAAYP 580 Query: 564 RNQQQRLRQPNLAQLGHPGDVGQGGLVHGGPVGGLAQPNFEREGGSTGAGRLGTFEQQAP 623 + Q Q+ +Q +Q P P L+Q +F + S + Q+ Sbjct: 581 QPQSQQSQQTAYSQQRFP------------PPQELSQDSFGSQASSAPSMTSSKGGQEDM 628 Query: 624 HLAQESAWFSGPHPPPG-DLLPRRMGG--------SGLPADCG---------------PH 659 +L+ +S S P D LP G SG+ + G PH Sbjct: 629 NLSLQSRPSSLPDLSGSIDDLPMGTEGALSPGVSTSGISSSQGEQSNPAQSPFSPHTSPH 688 Query: 660 DPSL-APPPPPGGSGVLF----RGPLQEPMRMPGEGHVPALPSPGLQFGGSLGGLGQLQS 714 P + P P P GS GPL P +PG P PS G + Sbjct: 689 LPGIRGPSPSPVGSPASVAQSRSGPL-SPAAVPGNQMPPRPPS------GQSDSIMHPSM 741 Query: 715 PGAGVGLPSAASERRPPPPDFATSALGGQPG---FPFGAAGRQSTPHSGPGVNSPPSAGG 771 + + +R P P +++ QPG P +G Q H+G G S G Sbjct: 742 NQSSIAQDRGYMQRNPQMPQYSSP----QPGSALSPRQPSGGQI--HTGMGSYQQNSMGS 795 Query: 772 GGGSSGGGGGGGAYPPQPDFQPSQRTSASKLGALSLGSFNKPSSKDNLFGQSCLAALSTA 831 G G G G YP QP++ + G G N + + GQ + T Sbjct: 796 YGPQGGQYGPQGGYPRQPNYNALPNANYPSAG--MAGGINPMGAGGQMHGQPGIPPYGTL 853 Query: 832 CQNMI--ASLG----APNL-----NVTFNKKNPPEGKRKLSQNETDGAAVAGN------P 874 + AS+G PN+ V PP G + +Q VA N P Sbjct: 854 PPGRMSHASMGNRPYGPNMANMPPQVGSGMCPPPGGMNRKTQETAVAMHVAANSIQNRPP 913 Query: 875 GSDYFPGGTAPGAPGPGGPSGTS-SSGSKASGPPNPPAQGDGTSLSPNYTLESTSGNDG- 932 G +P G G G P G +S + P PP GT + + + ++ G Sbjct: 914 G---YPNMNQGGMMGTGPPYGQGINSMAGMINPQGPPYSMGGTMANNSAGMAASPEMMGL 970 Query: 933 -----KPVSGGGGRGRGRRKRDS---GHVSPGTFFDKYSAAPDSGGAP----GVSPGQQQ 980 P + + G K +S S T +K + + GG P V Sbjct: 971 GDVKLTPATKMNNKADGTPKTESKSKKSSSSTTTNEKITKLYELGGEPERKMWVDRYLAF 1030 Query: 981 ASGAAVGGSSAGETRGAPTPHEKALTSPSWGKGAELLLGDQP--DLIGSLDGGAKSDSSS 1038 A+G ++ P + S G + ++ +L +L+ G S ++S Sbjct: 1031 TEEKAMGMTNLPAVGRKPLDLYRLYVSVKEIGGLTQVNKNKKWRELATNLNVGTSSSAAS 1090 Query: 1039 PNVGEFASDEVSTSYANEDEVSSSSDNPQALVKASRSPLVTGSPKL-PPRGVGAGE-HGP 1096 + YA E ++ D P + A+ S PK+ PP G+G GP Sbjct: 1091 ----SLKKQYIQCLYAFECKIERGEDPPPDIFAAADSK--KSQPKIQPPSPAGSGSMQGP 1144 Query: 1097 KAPPPALGLGIMSNSTSTPDSYGGGGGPGHPGTPGLEQV 1135 + P STS+ + GG P P + Q+ Sbjct: 1145 QTP----------QSTSSSMAEGGDLKPPTPASTPHSQI 1173 Score = 85.5 bits (210), Expect = 3e-16 Identities = 278/1302 (21%), Positives = 411/1302 (31%), Gaps = 271/1302 (20%) Query: 3 GLDQFE-PQVNSRNAGQGERNFNETGLSMNTHFK-APAFHTGGPPG--PVDPAMSALGEP 58 GL+ + PQ NS + G +N + + + APA+ P G P A +A G Sbjct: 191 GLEPYAGPQQNSHDHGFPNHQYNSYYPNRSAYPPPAPAYALSSPRGGTPGSGAAAAAGSK 250 Query: 59 PILGMNMEPYGFHARGHSELHAGGLQAQPVHGFFGGQQPHHGHPGSHHP----------- 107 P P A S + AQ G GG P G+ P Sbjct: 251 P-------PPSSSASASS---SSSSFAQQRFGAMGGGGPSAAGGGTPQPTATPTLNQLLT 300 Query: 108 -------HQHHPHFGGNF-GGPDPGASCLHGGRLLGYGGAAGGLGSQPPFAEGYEHMAES 159 +Q +P GG++ GGP G + + A + A G Sbjct: 301 SPSSARGYQGYP--GGDYSGGPQDGGAGKGPADMASQCWGAAAAAAAAAAASGGAQQRSH 358 Query: 160 QGPESFGPQRPGNLPDFHSSGASSHAVPAPCLPLDQSPNRAASFHGLPSSSGSDSHSLE- 218 P S G G P + P P P+DQ +G G++ +S + Sbjct: 359 HAPMSPGSSGGGGQPLART--------PQPSSPMDQMGKMRPQPYG-----GTNPYSQQQ 405 Query: 219 -PRRVTNQGAVDSLEYNYPGEAPSGHFDMFSPSDSEGQLPHYAAG----RQVPGGAFPGA 273 P QG + YPG+ P +G+ G +Q+P G Sbjct: 406 GPPSGPQQG------HGYPGQPYGSQTPQRYPMTMQGRAQSAMGGLSYTQQIPPYGQQGP 459 Query: 274 SAMPRAAGMVGLSKMHAQPPQQQPQQQQQPQQQQQQHGVFFERFSGARKMPVGLEPSVGS 333 S + ++ P QQQP QQP Q +PS Sbjct: 460 SGYGQQGQTPYYNQQSPHPQQQQPPYSQQPPSQTPH-----------------AQPSY-Q 501 Query: 334 RHPLMQPPQ-QAPPPPQQQPPQQPPQQQPPPP-PGLLVRQNSCPPALPRPQQGEAGTPSG 391 + P QPPQ Q+ PP Q P QPP QQ P P P P + P Q +A +P Sbjct: 502 QQPQSQPPQLQSSQPPYSQQPSQPPHQQSPAPYPSQQSTTQQHPQSQPPYSQPQAQSPYQ 561 Query: 392 GLQDGGPMLPSQHAQFEYPIHRLENRSMHPYSEPVFSMQHPPPQQAPNQRLQHFDAPPYM 451 Q P + Q YP + + YS+ F PP + + + + P M Sbjct: 562 QQQPQQPAPSTLSQQAAYPQPQSQQSQQTAYSQQRFP---PPQELSQDSFGSQASSAPSM 618 Query: 452 NVAK------------RPRF--DFPGS---------------AGVDRCASWNGSMHNGAL 482 +K RP D GS +S G N A Sbjct: 619 TSSKGGQEDMNLSLQSRPSSLPDLSGSIDDLPMGTEGALSPGVSTSGISSSQGEQSNPA- 677 Query: 483 DNHLSPSAYPGLPGEFTP-PVP----------------------DSFPSGPP------LQ 513 + SP P LPG P P P + P PP + Sbjct: 678 QSPFSPHTSPHLPGIRGPSPSPVGSPASVAQSRSGPLSPAAVPGNQMPPRPPSGQSDSIM 737 Query: 514 HPAPDHQSLQQQQQQQQQQQQQQQQQQQQQQQQQQQQRQNAALMIKQMASRNQQQR---- 569 HP+ + S+ Q + Q+ Q Q Q ++ + + M S Q Sbjct: 738 HPSMNQSSIAQDRGYMQRNPQMPQYSSPQPGSALSPRQPSGGQIHTGMGSYQQNSMGSYG 797 Query: 570 ------------LRQPNLAQL-----------GHPGDVGQGGLVHGGPVGGLAQPNFERE 606 RQPN L G +G GG +HG P G+ P Sbjct: 798 PQGGQYGPQGGYPRQPNYNALPNANYPSAGMAGGINPMGAGGQMHGQP--GIP-PYGTLP 854 Query: 607 GGSTGAGRLGTFEQQAPHLAQESAWF-SGPHPPPGDLLPRRMGGSGLPADCGPHDPSLAP 665 G +G P++A SG PPPG + R+ + + + P Sbjct: 855 PGRMSHASMGN-RPYGPNMANMPPQVGSGMCPPPGGM-NRKTQETAVAMHVAANSIQNRP 912 Query: 666 PP-------------PPGGSGVLFRGPLQEPMRMP-GEGHVPALPSPGLQFGGSLGGLGQ 711 P PP G G+ + P P G A S G+ + GLG Sbjct: 913 PGYPNMNQGGMMGTGPPYGQGINSMAGMINPQGPPYSMGGTMANNSAGMAASPEMMGLGD 972 Query: 712 LQSPGA------GVGLPSAASERRPPPPDFATSA-------LGGQPGFPFGAAGRQS-TP 757 ++ A G P S+ + T+ LGG+P + T Sbjct: 973 VKLTPATKMNNKADGTPKTESKSKKSSSSTTTNEKITKLYELGGEPERKMWVDRYLAFTE 1032 Query: 758 HSGPGVNSPPSAGGGGGSSGGGGGGGAYPPQPDFQPSQRTSASKLGALSLGSFNKPSSK- 816 G+ + P+ G +P S ++G L+ + NK + Sbjct: 1033 EKAMGMTNLPAVGR----------------KPLDLYRLYVSVKEIGGLTQVNKNKKWREL 1076 Query: 817 -DNLFGQSCLAALSTACQNMIASLGAPNLNVTFNKKNPPE----GKRKLSQNETDGAAVA 871 NL + +A S+ + I L A + + PP+ K SQ + + A Sbjct: 1077 ATNLNVGTSSSAASSLKKQYIQCLYAFECKIERGEDPPPDIFAAADSKKSQPKIQPPSPA 1136 Query: 872 GNPGSDYFPGGTAPGAPGPGGPSGTSSSGSKASGPPNPPAQGDGTSLSPNYTLESTSGND 931 G+ GP P TSSS ++ P S P S S + Sbjct: 1137 GSGSMQ-----------GPQTPQSTSSSMAEGGDLKPPTPASTPHSQIPPLPGMSRSNSV 1185 Query: 932 GKPVSGGGGRGRGRRKRDSGHVSPG--------TFFDKYSAAPDS----------GGAPG 973 G + G +KR+S +PG + S P+ G P Sbjct: 1186 GIQDAFNDGSDSTFQKRNSMTPNPGYQPSMNTSDMMGRMSYEPNKDPYGSMRKAPGSDPF 1245 Query: 974 VSPGQ----------QQASGAAVGGSSAGETRGAP--TPHEKALTSPSWGKGAELLLG-D 1020 +S GQ +A+G +G + G + P P+++ T P G + G Sbjct: 1246 MSSGQGPNGGMGDPYSRAAGPGLGNVAMGPRQHYPYGGPYDRVRTEPGIGPEGNMSTGAP 1305 Query: 1021 QPDLIGS-LDGGAKSDSSSPNVGEFASDEVSTSYANE---DEVSSSSDNPQALVKASRSP 1076 QP+L+ S D G S S P + + SY N+ S S P + Sbjct: 1306 QPNLMPSNPDSGMYSPSRYPPQQQQQQQQRHDSYGNQFSTQGTPSGSPFPSQQTTMYQQQ 1365 Query: 1077 LVTGSPKLPPRGVGAGEHGPKAPPPALGLGIMSNSTSTPDSY 1118 SP PR + K+P G+ + P S+ Sbjct: 1366 QQVSSPAPLPRPMENRTSPSKSPFLHSGMKMQKAGPPVPASH 1407 Score = 60.1 bits (144), Expect = 1e-08 Identities = 130/561 (23%), Positives = 180/561 (32%), Gaps = 112/561 (19%) Query: 661 PSLAPPPPPG------------------GSGVLFRGPLQEPMRMPGEGHVPALPSPGLQF 702 P++ PP P G GSG GP EP G+ P+ Sbjct: 61 PAVGPPQPLGKELQDGAESNGGGGGGGAGSG---GGPGAEPDLKNSNGNAGPRPALNNNL 117 Query: 703 GGSLGGLGQLQSPGAGVGLPSAASERRPPPPDFATSALGGQPGFPFGAAG----RQSTPH 758 GG G S G G SAA+ PP F G P AA +Q Sbjct: 118 TEPPGGGGGGSSDGVGAPPHSAAAALPPPAYGFG-QPYGRSPSAVAAAAAAVFHQQHGGQ 176 Query: 759 SGPGVNSPPSAGGGGGSSGGG-------------------GGGGAYPPQPDFQPSQRTSA 799 PG+ + S GGGG G AYPP P+ S+ Sbjct: 177 QSPGLAALQSGGGGGLEPYAGPQQNSHDHGFPNHQYNSYYPNRSAYPPP---APAYALSS 233 Query: 800 SKLG------ALSLGSFNKPSSKDNLFGQSCLAALSTACQNMIASLGAPNLNVTFNKKNP 853 + G A + GS PSS S ++ S+ Q ++G + Sbjct: 234 PRGGTPGSGAAAAAGSKPPPSS-----SASASSSSSSFAQQRFGAMGGGGPSAAGGGTPQ 288 Query: 854 PEGKRKLSQNETDGAAVAGNPGSDYFPGGTAPGAPGPG----GPSGTSSSGSKASGPPNP 909 P L+Q T ++ G G +PGG G P G GP+ +S A+ Sbjct: 289 PTATPTLNQLLTSPSSARGYQG---YPGGDYSGGPQDGGAGKGPADMASQCWGAAAAAAA 345 Query: 910 PAQGDGTSLSPNYTLESTSGNDGKPVSGGGGRGRGRRKRDSGHVSPGTFFDKYSAAPDSG 969 A G + ++ + G+ SGGGG+ R + S SP K P G Sbjct: 346 AAAASGGAQQRSHHAPMSPGS-----SGGGGQPLARTPQPS---SPMDQMGKMRPQP-YG 396 Query: 970 GAPGVSPGQQQASGAAVGGSSAGETRGAPTPHEKALTSPSWGKGAELLLGDQPDLIGSLD 1029 G S Q SG G G+ G+ TP +T + A Sbjct: 397 GTNPYSQQQGPPSGPQQGHGYPGQPYGSQTPQRYPMTMQGRAQSAM-------------- 442 Query: 1030 GGAKSDSSSPNVGEFA----SDEVSTSYANEDEVSSSSDNPQALVKASRSPLVTGSPKLP 1085 GG P G+ + T Y N+ S +PQ + P P Sbjct: 443 GGLSYTQQIPPYGQQGPSGYGQQGQTPYYNQ-----QSPHPQ----QQQPPYSQQPPSQT 493 Query: 1086 PRGVGAGEHGPKAPPPALGLGIMSNSTSTPDSYGGGGGPGHPGTPGLEQVRTPTSSSGAP 1145 P + + P++ PP L +S P P H +P + T+ Sbjct: 494 PHAQPSYQQQPQSQPPQL-------QSSQPPYSQQPSQPPHQQSPAPYPSQQSTTQQ--- 543 Query: 1146 PPDEIHPLEILQAQIQLQRQQ 1166 P P QAQ Q+QQ Sbjct: 544 HPQSQPPYSQPQAQSPYQQQQ 564 Score = 57.4 bits (137), Expect = 9e-08 Identities = 107/440 (24%), Positives = 143/440 (32%), Gaps = 72/440 (16%) Query: 721 LPSAASERRPPPPDFATSALGGQPGFPFGAAGRQSTPHSGPGVNSPP------------S 768 L A ++R A +A + G AAG++S GP V P + Sbjct: 24 LKKAEQQQREEAGGEAAAAAAAERGEMKAAAGQES---EGPAVGPPQPLGKELQDGAESN 80 Query: 769 AGGGGGSSGGGGGGGAYPPQPDFQPSQRTSASKLGALSLGSFNKPSSKDNLFGQSCLAAL 828 GGGGG +G GGG GA +PD + S +A AL+ P G + Sbjct: 81 GGGGGGGAGSGGGPGA---EPDLKNS-NGNAGPRPALNNNLTEPPGGG----GGGSSDGV 132 Query: 829 STACQNMIASLGAPNLNVTFNKKNPPEGKRKLSQNETDGAAVAGNPGSDYFPGGTAPGAP 888 + A+L P P G+ + A G PG A + Sbjct: 133 GAPPHSAAAALPPPAYGF-----GQPYGRSPSAVAAAAAAVFHQQHGGQQSPGLAALQSG 187 Query: 889 GPGG--PSGTSSSGSKASGPPNP------PAQGDGTSLSPNYTLESTSGNDGKPVSGGGG 940 G GG P S G PN P + +P Y L S G G P SG Sbjct: 188 GGGGLEPYAGPQQNSHDHGFPNHQYNSYYPNRSAYPPPAPAYALSSPRG--GTPGSGAAA 245 Query: 941 RGRGRRKRDSGHVSPGTFFDKYSAAPDSGGAPGVSPGQQQASGAAVGGSSAGETRGAPTP 1000 + S SA+ S S QQ GA GG + G P P Sbjct: 246 AAGSKPPPSS------------SASASSSS----SSFAQQRFGAMGGGGPSAAGGGTPQP 289 Query: 1001 H-----EKALTSPSWGKGAELLLGDQPDLIGSLDGGAKSDSSSPNVGEFASDEVSTSYAN 1055 + LTSPS +G + G G GG + + + AS + A Sbjct: 290 TATPTLNQLLTSPSSARGYQGYPG------GDYSGGPQDGGAGKGPADMASQCWGAAAAA 343 Query: 1056 EDEVSSSSDNPQALVKASRSPLVTGS-----PKLPPRGVGAGEHGPKAPPPALGLGIMSN 1110 ++S Q A SP +G + P + G P P G S Sbjct: 344 AAAAAASGGAQQRSHHAPMSPGSSGGGGQPLARTPQPSSPMDQMGKMRPQPYGGTNPYSQ 403 Query: 1111 STSTPDSYGGGGGPGHPGTP 1130 P G G G+PG P Sbjct: 404 QQGPPS--GPQQGHGYPGQP 421 Score = 52.4 bits (124), Expect = 3e-06 Identities = 85/329 (25%), Positives = 116/329 (35%), Gaps = 82/329 (24%) Query: 853 PPEGKRKLSQNETDGAAVAGNPGSDYFPGGTAPGAPGPGGPSGTSSSGSKASGPPNPPAQ 912 PP +K Q + + A GG A A +++G ++ GP P Q Sbjct: 20 PPSELKKAEQQQREEA------------GGEAAAAAAAERGEMKAAAGQESEGPAVGPPQ 67 Query: 913 GDGTSLSPNYTLESTSGNDGKPVSGGGGRGRGRRKRDSGHVSPGTFFDKYSAAPDSGGAP 972 G L ES G G GG G G G PG D ++ ++G P Sbjct: 68 PLGKELQDG--AESNGGGGG----GGAGSGGG----------PGAEPDLKNSNGNAGPRP 111 Query: 973 GVSPGQQQASGAAVGGSSAGETRGAPTPHEKALTSPSWGKGAELLLGDQPDLI------- 1025 ++ + G GGSS G GAP PH A P G G P + Sbjct: 112 ALNNNLTEPPGGGGGGSSDGV--GAP-PHSAAAALPPPAYGFGQPYGRSPSAVAAAAAAV 168 Query: 1026 ---------------------GSLDGGAKSDSSSPNVGEFASDEVSTSYANEDEVSSSSD 1064 G L+ A +S + G F + + ++ Y N S+ Sbjct: 169 FHQQHGGQQSPGLAALQSGGGGGLEPYAGPQQNSHDHG-FPNHQYNSYYPNR-----SAY 222 Query: 1065 NPQALVKASRSPLVTGSPKLPPRGVGAGEHGPKAPPPALGLGIMSNSTS-TPDSYG--GG 1121 P A A SP G+P G GA PPP+ S+S+S +G GG Sbjct: 223 PPPAPAYALSSPR-GGTP-----GSGAAAAAGSKPPPSSSASASSSSSSFAQQRFGAMGG 276 Query: 1122 GGPGHPG--------TPGLEQVRTPTSSS 1142 GGP G TP L Q+ T SS+ Sbjct: 277 GGPSAAGGGTPQPTATPTLNQLLTSPSSA 305 Score = 32.0 bits (71), Expect = 4.0 Identities = 20/59 (33%), Positives = 26/59 (44%), Gaps = 3/59 (5%) Query: 1090 GAGEHGPKA-PPPALGLGIMSNSTSTPDSYGGGGGPGHPGTPGLEQVRTPTSSSGAPPP 1147 G GP PP LG + + S + GGGGG G G PG E ++ + P P Sbjct: 55 GQESEGPAVGPPQPLGKELQDGAES--NGGGGGGGAGSGGGPGAEPDLKNSNGNAGPRP 111 >gi|111118976 collagen, type II, alpha 1 isoform 1 precursor [Homo sapiens] Length = 1487 Score = 102 bits (253), Expect = 3e-21 Identities = 288/1172 (24%), Positives = 360/1172 (30%), Gaps = 229/1172 (19%) Query: 43 GPPGPVDPAMS--ALGEPPILGMNMEPYGFHARGHSELHAGGLQAQPVHGFFGGQQPHHG 100 GPPGP G+P G P ARG GL H + G G Sbjct: 243 GPPGPPGKPGDDGEAGKPGKAGERGPPGPQGARGFPG--TPGLPGVKGHRGYPGLDGAKG 300 Query: 101 HPGSHHPHQHHPHFGGNFGGPDP-GASCLHGGRLLGYGGAAGGLGSQPPFAEGYEHMAES 159 G+ G N G P P G L G R G G AG G A G + Sbjct: 301 EAGAPGVKGESGSPGEN-GSPGPMGPRGLPGER--GRTGPAGAAG-----ARGNDGQPGP 352 Query: 160 QGPESFGPQRPGNLPDFHSS-GASSHAVPAPCLPLDQSPNRAASFHGLPSSSGSDSHSLE 218 GP GP P P F + GA A P + P A G P + GS Sbjct: 353 AGPP--GPVGPAGGPGFPGAPGAKGEAGPTGA----RGPEGAQGPRGEPGTPGSPG---- 402 Query: 219 PRRVTNQGAVDSL-----EYNYPGEAPSGHFDMFSPSDSEGQLPHYAAGRQVPGGAFPGA 273 P + D + PG A + F P G P A G P G Sbjct: 403 PAGASGNPGTDGIPGAKGSAGAPGIAGAPGFP--GPRGPPG--PQGATGPLGP----KGQ 454 Query: 274 SAMPRAAGMVGLSKMHAQPPQQQPQQQQQPQQQQQQHGVFFERFSGARKMPVGLEPSVGS 333 + P AG G +P PQ P ++ + G AR P G+ P Sbjct: 455 TGEPGIAGFKGEQGPKGEPGPAGPQGAPGPAGEEGKRG--------ARGEPGGVGP---- 502 Query: 334 RHPLMQPPQQAPPPPQQQPPQQPPQQQPPPPPGLLVRQNSCPPALPRPQQGEAGTPSGGL 393 + PP + P + P Q P PG + A P+ G+ G P Sbjct: 503 ----IGPPGERGAPGNRGFPGQDGLAGPKGAPG---ERGPSGLAGPKGANGDPGRP---- 551 Query: 394 QDGGPMLPSQHAQFEYPIHRLENRSMHPYSEPVFSMQHPPP--QQAPNQR-LQHFDAPPY 450 G P LP P + P P + PP Q A Q + F P Sbjct: 552 --GEPGLPGARGLTGRPGDAGPQGKVGPSGAPGEDGRPGPPGPQGARGQPGVMGFPGPKG 609 Query: 451 MN--VAKRPRFDFPGSAGVDRCASWNGSMHNGALDNHLSPSAYPGLPGEFTPPVPDSF-- 506 N K PG+ G+ +G GA P+ G GE P P F Sbjct: 610 ANGEPGKAGEKGLPGAPGLRGLPGKDGE--TGAAGPP-GPAGPAGERGEQGAPGPSGFQG 666 Query: 507 ---PSGPPLQHPAPDHQSLQQQQQQQQQQQQQQQQQQQQQQQQQQQQRQNAALMIKQMAS 563 P GPP + P Q + + A ++ Sbjct: 667 LPGPPGPPGEGGKPGDQGVPGEA--------------------------GAPGLVGPRGE 700 Query: 564 RNQQQRLRQPNLAQL-------GHPGDVG-QGGLVHGGPVGGLAQPNFEREGGSTGAGRL 615 R P L G PG G +G GP G P + G GA + Sbjct: 701 RGFPGERGSPGAQGLQGPRGLPGTPGTDGPKGASGPAGPPGAQGPPGLQGMPGERGAAGI 760 Query: 616 GTFEQQAPHLAQESAWFSGPHPPPGDLLPRRMGGSGLPADCGPHDPS--------LAPPP 667 P + GP PG + GG GL GP P+ + PP Sbjct: 761 A-----GPKGDRGDVGEKGPEGAPG-----KDGGRGLTGPIGPPGPAGANGEKGEVGPPG 810 Query: 668 PPGGSGVLFRGPLQEPMRMPGEGHVPALPSPGLQFG--GSLGGLGQLQSPGA-GVGLPSA 724 P G +G + PG P Q G G G GQ GA G PS Sbjct: 811 PAGSAGARGAPGERGETGPPGPAGFAGPPGADGQPGAKGEQGEAGQKGDAGAPGPQGPSG 870 Query: 725 ASERRPPP----PDFATSALG--GQPGFPFGAAGRQSTPHSG--PGVNSPPSAGGGGGSS 776 A + P P A A G G GFP GAAGR P S PG PP G G Sbjct: 871 APGPQGPTGVTGPKGARGAQGPPGATGFP-GAAGRVGPPGSNGNPGPPGPPGPSGKDGPK 929 Query: 777 GGGGGGGAYPPQPDFQPSQRTSASKLGALSLGSFNKPSSKDNLFGQSCLAALSTACQNMI 836 G G G PP +P + A G + PS + G LA Q I Sbjct: 930 GARGDSG--PPGRAGEPGLQGPAGPPGEKGEPGDDGPSGAEGPPGPQGLAG-----QRGI 982 Query: 837 ASLGAPNLNVTFNKKNPPEGKRKLSQNETDGAAVAGNPGSDYFPGGTAP-GAPGPGGPSG 895 L F P G+ PG PG + G PGP GP G Sbjct: 983 VGLPGQRGERGFPGLPGPSGE----------------PGKQGAPGASGDRGPPGPVGPPG 1026 Query: 896 TSSSGSKASGPPNPPAQGDGTSLSPNYTLESTSGNDGKPVSGGGGRGRGRRKRDSGHVSP 955 + GP P + E + G DG P G +G R +P Sbjct: 1027 LT-------GPAGEPGR------------EGSPGADGPPGRDGAAGVKGDRGETGAVGAP 1067 Query: 956 GTFFDKYSAAPDSGGAPGVS--PGQQQASGAAVGGSSAGETRGAPTPHEKALTSPSWGKG 1013 G AP G+PG + G+Q G A GA P PS G Sbjct: 1068 G--------APGPPGSPGPAGPTGKQGDRGEA----------GAQGP-----MGPSGPAG 1104 Query: 1014 AELLLGDQPDLIGSLDGGAKSDSSSPNVGEFASDEVSTSYANEDEVSSSSDNPQALVKAS 1073 A + G Q G K ++ P T S + + + Sbjct: 1105 ARGIQGPQGPR------GDKGEAGEPGERGLKGHRGFTGLQGLPGPPGPSGD-----QGA 1153 Query: 1074 RSPLVTGSPKLPPRGVGA-------GEHGPKAPPPALGLGIMSNSTSTPDSYGGGGGPGH 1126 P P+ PP VG G GP PP G + P + G G PG Sbjct: 1154 SGPAGPSGPRGPPGPVGPSGKDGANGIPGPIGPPGPRGRSGETGPAGPPGNPGPPGPPGP 1213 Query: 1127 PGTPGLEQVRTPTSSSGAPPPDEIHPLEILQA 1158 PG PG++ PD PL+ ++A Sbjct: 1214 PG-PGIDMSAFAGLGPREKGPD---PLQYMRA 1241 Score = 94.7 bits (234), Expect = 5e-19 Identities = 188/723 (26%), Positives = 227/723 (31%), Gaps = 115/723 (15%) Query: 577 QLGHPGDVG----QGGLVHGGPVGGLAQPNFEREGGSTGA----GRLGTFEQQAPHLAQE 628 Q G PG G QG GP G P E G GA G +G A Sbjct: 454 QTGEPGIAGFKGEQGPKGEPGPAGPQGAPGPAGEEGKRGARGEPGGVGPIGPPGERGAPG 513 Query: 629 SAWF------SGPHPPPGDLLPRRMGG-SGLPADCG-PHDPSLAPPPPPGGSGVLFR--- 677 + F +GP PG+ P + G G D G P +P L PG G+ R Sbjct: 514 NRGFPGQDGLAGPKGAPGERGPSGLAGPKGANGDPGRPGEPGL-----PGARGLTGRPGD 568 Query: 678 -GPLQE--PMRMPGEGHVPALPSPG--------LQFGGSLGGLGQLQSPGAGVGLPSAAS 726 GP + P PGE P P P + F G G G+ G GLP A Sbjct: 569 AGPQGKVGPSGAPGEDGRPGPPGPQGARGQPGVMGFPGPKGANGEPGKAGEK-GLPGAPG 627 Query: 727 ERRPPPPDFATSALGGQ-PGFPFGAAGRQSTPHSG-----PGVNSPPSAGGGGGSSGGGG 780 R P D T A G P P G G Q P PG PP GG G G G Sbjct: 628 LRGLPGKDGETGAAGPPGPAGPAGERGEQGAPGPSGFQGLPGPPGPPGEGGKPGDQGVPG 687 Query: 781 GGGAY----PPQPDFQPSQRTSASKLGALSLGSFNKPSSKDNLFGQSCLAALSTACQNMI 836 GA P P +R S G D G S A A Q Sbjct: 688 EAGAPGLVGPRGERGFPGERGSPGAQGLQGPRGLPGTPGTDGPKGASGPAGPPGA-QGPP 746 Query: 837 ASLGAPNLNVTFNKKNPPEGKRKLSQNETDGAAVAGNPGSDYFPGGTAP-GAPGPGGPSG 895 G P P + + + +GA PG D G T P G PGP G +G Sbjct: 747 GLQGMPGERGAAGIAGPKGDRGDVGEKGPEGA-----PGKDGGRGLTGPIGPPGPAGANG 801 Query: 896 TSSSGSKASGPPNP---------PAQGDGTSLSPNYTLESTSGNDGKPVSGGGGRGRGRR 946 GPP P P + T G DG+P G +G + Sbjct: 802 EKGE----VGPPGPAGSAGARGAPGERGETGPPGPAGFAGPPGADGQP-GAKGEQGEAGQ 856 Query: 947 KRDSGHVSPGTFFDKYSAAPDSGGAPGVSPGQQQASGA-----AVGGSSAGETRGAP--- 998 K D+G P S AP G GV+ G + A GA A G A G P Sbjct: 857 KGDAGAPGP----QGPSGAPGPQGPTGVT-GPKGARGAQGPPGATGFPGAAGRVGPPGSN 911 Query: 999 -TPHEKALTSPSWGKGAELLLGDQPDLIGSLDGGAKSDSSSPNVGEFASDEVSTSYANED 1057 P PS G + GD G + P + A +D Sbjct: 912 GNPGPPGPPGPSGKDGPKGARGDS---------GPPGRAGEPGLQGPAGPPGEKGEPGDD 962 Query: 1058 EVSSSSDNPQALVKASRSPLV--------TGSPKLP-----PRGVGA----GEHGPKAPP 1100 S + P A + +V G P LP P GA G+ GP P Sbjct: 963 GPSGAEGPPGPQGLAGQRGIVGLPGQRGERGFPGLPGPSGEPGKQGAPGASGDRGPPGPV 1022 Query: 1101 PALGLGIMSNSTSTPDSYGGGGGPGHPGTPGLEQVRTPTSSSGAP----PPDEIHPLEIL 1156 GL + S G G PG G G++ R T + GAP PP P Sbjct: 1023 GPPGLTGPAGEPGREGSPGADGPPGRDGAAGVKGDRGETGAVGAPGAPGPPGSPGP---- 1078 Query: 1157 QAQIQLQRQQFSISEDQPLGLKGGKKGECAVGASGAQNGDSELGSCCSEAVKSAMSTIDL 1216 Q + P+G G G G + E G +K L Sbjct: 1079 AGPTGKQGDRGEAGAQGPMGPSGPAGARGIQGPQGPRGDKGEAGEPGERGLKGHRGFTGL 1138 Query: 1217 DSL 1219 L Sbjct: 1139 QGL 1141 Score = 81.3 bits (199), Expect = 6e-15 Identities = 155/605 (25%), Positives = 189/605 (31%), Gaps = 109/605 (18%) Query: 593 GPVGGLAQPNFERE--GGSTGAGRLGTFEQQAPHLAQESAWFSGPHPPPGDLLPRRMGGS 650 GP G +P ++ G G G +Q P + G P G R G Sbjct: 101 GPKGQKGEPGDIKDIVGPKGPPGPQGPAGEQGPRGDRGDKGEKGAPGPRG-----RDGEP 155 Query: 651 GLPADCGPHDPSLAPPPPPG---------------GSGVLFRGPLQEPMRMPGEGHVPA- 694 G P + GP P PP PPG +G G +Q PM G P Sbjct: 156 GTPGNPGPPGPP-GPPGPPGLGGNFAAQMAGGFDEKAGGAQLGVMQGPMGPMGPRGPPGP 214 Query: 695 LPSPGLQ-------------FGGSLGGLGQLQSPG-----AGVGLPSAASERRPPPPDFA 736 +PG Q G +G G PG G P A ER PP P A Sbjct: 215 AGAPGPQGFQGNPGEPGEPGVSGPMGPRGPPGPPGKPGDDGEAGKPGKAGERGPPGPQGA 274 Query: 737 TSALGGQPGFPFGAAGRQSTP--HSGPGVNSPPSAGGGGGSSGGGGGGGAYPPQPDFQPS 794 G PG P G G + P G P G GS G G G P P P Sbjct: 275 -RGFPGTPGLP-GVKGHRGYPGLDGAKGEAGAPGVKGESGSPGENGSPG--PMGPRGLPG 330 Query: 795 QRTSASKLGALSLGSFN---KPSSKDNLFGQSCLAALSTACQNMIASLGAPNLNVTFNKK 851 +R GA + P+ G + + GA + Sbjct: 331 ERGRTGPAGAAGARGNDGQPGPAGPPGPVGPA-------GGPGFPGAPGAKGEAGPTGAR 383 Query: 852 NPPEGKRKLSQNETDG----AAVAGNPGSDYFPGGT-APGAPGPGGPSGTSSSGSKASGP 906 P + + T G A +GNPG+D PG + GAPG G G GP Sbjct: 384 GPEGAQGPRGEPGTPGSPGPAGASGNPGTDGIPGAKGSAGAPGIAGAPGFPG----PRGP 439 Query: 907 PNPPAQGDGTSLSPNYTLESTSGNDGKPVSGGGGRGRGRRKRDSGHVSPGTFFDKYSAAP 966 P P QG L P G G+P G +G K + G P AP Sbjct: 440 PGP--QGATGPLGP-------KGQTGEP-GIAGFKGEQGPKGEPGPAGP-------QGAP 482 Query: 967 DSGGAPGVSPGQQQASGAAVGGSSAGETRGAP----TPHEKALTSPSWGKGAELLLGDQP 1022 G G + + G VG RGAP P + L P G G Sbjct: 483 GPAGEEGKRGARGEPGG--VGPIGPPGERGAPGNRGFPGQDGLAGPKGAPGERGPSG--- 537 Query: 1023 DLIGSLDGGAKSDSSSPNVGEFASDEVSTSYANEDEVSSSSDNPQALVKASRSPLVTGSP 1082 L G GA D P E A PQ V S +P G P Sbjct: 538 -LAG--PKGANGDPGRPG-------EPGLPGARGLTGRPGDAGPQGKVGPSGAPGEDGRP 587 Query: 1083 KLPPRGVGAGEHGPKAPPPALGLGIMSNSTSTPDSYGGGGGPGHPGTPGLEQVRTPTSSS 1142 P G G + P +G + P G G PG PG GL T ++ Sbjct: 588 GPP------GPQGARGQPGVMGFPGPKGANGEPGKAGEKGLPGAPGLRGLPGKDGETGAA 641 Query: 1143 GAPPP 1147 G P P Sbjct: 642 GPPGP 646 Score = 43.1 bits (100), Expect = 0.002 Identities = 85/320 (26%), Positives = 110/320 (34%), Gaps = 65/320 (20%) Query: 883 TAPGAPGPGGPSGTSSSGSKASGPPNPPA-QGDGTSLSPNYTLESTSGNDGKPVSGGGGR 941 TA G PGP G G GP PP QG P G G P Sbjct: 95 TASGQPGPKGQKGEPGDIKDIVGPKGPPGPQGPAGEQGPRGD-RGDKGEKGAP------- 146 Query: 942 GRGRRKRDSGHVSPGTFFDKYSAAPDSGGAPGVSPGQQQASGAAVGGSSAGETRGAPTPH 1001 G R RD PGT P + G PG PG G +GG+ A + G Sbjct: 147 --GPRGRDG---EPGT--------PGNPGPPG-PPGPPGPPG--LGGNFAAQMAGGFD-- 188 Query: 1002 EKALTSPSWGKGAELLLGDQPDLIGSLDG-GAKSDSSSPNVGEFASDEVSTSYANEDEVS 1060 EKA GA+L + P +G + G + +P F + E VS Sbjct: 189 EKA-------GGAQLGVMQGP--MGPMGPRGPPGPAGAPGPQGFQGNP---GEPGEPGVS 236 Query: 1061 SSSDNPQALVKASRSPLVTGSPKLPPRGVGAGEHGPKAPPPALGLGIMSNSTSTPDSYGG 1120 P+ P G P + AGE GP P A G P + G Sbjct: 237 GPM-GPRGPPGPPGKPGDDGEAGKPGK---AGERGPPGPQGARGF---------PGTPGL 283 Query: 1121 GGGPGHPGTPGLEQVRTPTSSSGAPPPDEIHPLEILQAQIQLQRQQFSISEDQPLGLKGG 1180 G GH G PGL+ + +GAP ++ + + S P GL G Sbjct: 284 PGVKGHRGYPGLDGAK---GEAGAPG---------VKGESGSPGENGSPGPMGPRGLPGE 331 Query: 1181 KKGECAVGASGAQNGDSELG 1200 + GA+GA+ D + G Sbjct: 332 RGRTGPAGAAGARGNDGQPG 351 >gi|111118974 collagen, type II, alpha 1 isoform 2 precursor [Homo sapiens] Length = 1418 Score = 102 bits (253), Expect = 3e-21 Identities = 288/1172 (24%), Positives = 360/1172 (30%), Gaps = 229/1172 (19%) Query: 43 GPPGPVDPAMS--ALGEPPILGMNMEPYGFHARGHSELHAGGLQAQPVHGFFGGQQPHHG 100 GPPGP G+P G P ARG GL H + G G Sbjct: 174 GPPGPPGKPGDDGEAGKPGKAGERGPPGPQGARGFPG--TPGLPGVKGHRGYPGLDGAKG 231 Query: 101 HPGSHHPHQHHPHFGGNFGGPDP-GASCLHGGRLLGYGGAAGGLGSQPPFAEGYEHMAES 159 G+ G N G P P G L G R G G AG G A G + Sbjct: 232 EAGAPGVKGESGSPGEN-GSPGPMGPRGLPGER--GRTGPAGAAG-----ARGNDGQPGP 283 Query: 160 QGPESFGPQRPGNLPDFHSS-GASSHAVPAPCLPLDQSPNRAASFHGLPSSSGSDSHSLE 218 GP GP P P F + GA A P + P A G P + GS Sbjct: 284 AGPP--GPVGPAGGPGFPGAPGAKGEAGPTGA----RGPEGAQGPRGEPGTPGSPG---- 333 Query: 219 PRRVTNQGAVDSL-----EYNYPGEAPSGHFDMFSPSDSEGQLPHYAAGRQVPGGAFPGA 273 P + D + PG A + F P G P A G P G Sbjct: 334 PAGASGNPGTDGIPGAKGSAGAPGIAGAPGFP--GPRGPPG--PQGATGPLGP----KGQ 385 Query: 274 SAMPRAAGMVGLSKMHAQPPQQQPQQQQQPQQQQQQHGVFFERFSGARKMPVGLEPSVGS 333 + P AG G +P PQ P ++ + G AR P G+ P Sbjct: 386 TGEPGIAGFKGEQGPKGEPGPAGPQGAPGPAGEEGKRG--------ARGEPGGVGP---- 433 Query: 334 RHPLMQPPQQAPPPPQQQPPQQPPQQQPPPPPGLLVRQNSCPPALPRPQQGEAGTPSGGL 393 + PP + P + P Q P PG + A P+ G+ G P Sbjct: 434 ----IGPPGERGAPGNRGFPGQDGLAGPKGAPG---ERGPSGLAGPKGANGDPGRP---- 482 Query: 394 QDGGPMLPSQHAQFEYPIHRLENRSMHPYSEPVFSMQHPPP--QQAPNQR-LQHFDAPPY 450 G P LP P + P P + PP Q A Q + F P Sbjct: 483 --GEPGLPGARGLTGRPGDAGPQGKVGPSGAPGEDGRPGPPGPQGARGQPGVMGFPGPKG 540 Query: 451 MN--VAKRPRFDFPGSAGVDRCASWNGSMHNGALDNHLSPSAYPGLPGEFTPPVPDSF-- 506 N K PG+ G+ +G GA P+ G GE P P F Sbjct: 541 ANGEPGKAGEKGLPGAPGLRGLPGKDGE--TGAAGPP-GPAGPAGERGEQGAPGPSGFQG 597 Query: 507 ---PSGPPLQHPAPDHQSLQQQQQQQQQQQQQQQQQQQQQQQQQQQQRQNAALMIKQMAS 563 P GPP + P Q + + A ++ Sbjct: 598 LPGPPGPPGEGGKPGDQGVPGEA--------------------------GAPGLVGPRGE 631 Query: 564 RNQQQRLRQPNLAQL-------GHPGDVG-QGGLVHGGPVGGLAQPNFEREGGSTGAGRL 615 R P L G PG G +G GP G P + G GA + Sbjct: 632 RGFPGERGSPGAQGLQGPRGLPGTPGTDGPKGASGPAGPPGAQGPPGLQGMPGERGAAGI 691 Query: 616 GTFEQQAPHLAQESAWFSGPHPPPGDLLPRRMGGSGLPADCGPHDPS--------LAPPP 667 P + GP PG + GG GL GP P+ + PP Sbjct: 692 A-----GPKGDRGDVGEKGPEGAPG-----KDGGRGLTGPIGPPGPAGANGEKGEVGPPG 741 Query: 668 PPGGSGVLFRGPLQEPMRMPGEGHVPALPSPGLQFG--GSLGGLGQLQSPGA-GVGLPSA 724 P G +G + PG P Q G G G GQ GA G PS Sbjct: 742 PAGSAGARGAPGERGETGPPGPAGFAGPPGADGQPGAKGEQGEAGQKGDAGAPGPQGPSG 801 Query: 725 ASERRPPP----PDFATSALG--GQPGFPFGAAGRQSTPHSG--PGVNSPPSAGGGGGSS 776 A + P P A A G G GFP GAAGR P S PG PP G G Sbjct: 802 APGPQGPTGVTGPKGARGAQGPPGATGFP-GAAGRVGPPGSNGNPGPPGPPGPSGKDGPK 860 Query: 777 GGGGGGGAYPPQPDFQPSQRTSASKLGALSLGSFNKPSSKDNLFGQSCLAALSTACQNMI 836 G G G PP +P + A G + PS + G LA Q I Sbjct: 861 GARGDSG--PPGRAGEPGLQGPAGPPGEKGEPGDDGPSGAEGPPGPQGLAG-----QRGI 913 Query: 837 ASLGAPNLNVTFNKKNPPEGKRKLSQNETDGAAVAGNPGSDYFPGGTAP-GAPGPGGPSG 895 L F P G+ PG PG + G PGP GP G Sbjct: 914 VGLPGQRGERGFPGLPGPSGE----------------PGKQGAPGASGDRGPPGPVGPPG 957 Query: 896 TSSSGSKASGPPNPPAQGDGTSLSPNYTLESTSGNDGKPVSGGGGRGRGRRKRDSGHVSP 955 + GP P + E + G DG P G +G R +P Sbjct: 958 LT-------GPAGEPGR------------EGSPGADGPPGRDGAAGVKGDRGETGAVGAP 998 Query: 956 GTFFDKYSAAPDSGGAPGVS--PGQQQASGAAVGGSSAGETRGAPTPHEKALTSPSWGKG 1013 G AP G+PG + G+Q G A GA P PS G Sbjct: 999 G--------APGPPGSPGPAGPTGKQGDRGEA----------GAQGP-----MGPSGPAG 1035 Query: 1014 AELLLGDQPDLIGSLDGGAKSDSSSPNVGEFASDEVSTSYANEDEVSSSSDNPQALVKAS 1073 A + G Q G K ++ P T S + + + Sbjct: 1036 ARGIQGPQGPR------GDKGEAGEPGERGLKGHRGFTGLQGLPGPPGPSGD-----QGA 1084 Query: 1074 RSPLVTGSPKLPPRGVGA-------GEHGPKAPPPALGLGIMSNSTSTPDSYGGGGGPGH 1126 P P+ PP VG G GP PP G + P + G G PG Sbjct: 1085 SGPAGPSGPRGPPGPVGPSGKDGANGIPGPIGPPGPRGRSGETGPAGPPGNPGPPGPPGP 1144 Query: 1127 PGTPGLEQVRTPTSSSGAPPPDEIHPLEILQA 1158 PG PG++ PD PL+ ++A Sbjct: 1145 PG-PGIDMSAFAGLGPREKGPD---PLQYMRA 1172 Score = 94.7 bits (234), Expect = 5e-19 Identities = 188/723 (26%), Positives = 227/723 (31%), Gaps = 115/723 (15%) Query: 577 QLGHPGDVG----QGGLVHGGPVGGLAQPNFEREGGSTGA----GRLGTFEQQAPHLAQE 628 Q G PG G QG GP G P E G GA G +G A Sbjct: 385 QTGEPGIAGFKGEQGPKGEPGPAGPQGAPGPAGEEGKRGARGEPGGVGPIGPPGERGAPG 444 Query: 629 SAWF------SGPHPPPGDLLPRRMGG-SGLPADCG-PHDPSLAPPPPPGGSGVLFR--- 677 + F +GP PG+ P + G G D G P +P L PG G+ R Sbjct: 445 NRGFPGQDGLAGPKGAPGERGPSGLAGPKGANGDPGRPGEPGL-----PGARGLTGRPGD 499 Query: 678 -GPLQE--PMRMPGEGHVPALPSPG--------LQFGGSLGGLGQLQSPGAGVGLPSAAS 726 GP + P PGE P P P + F G G G+ G GLP A Sbjct: 500 AGPQGKVGPSGAPGEDGRPGPPGPQGARGQPGVMGFPGPKGANGEPGKAGEK-GLPGAPG 558 Query: 727 ERRPPPPDFATSALGGQ-PGFPFGAAGRQSTPHSG-----PGVNSPPSAGGGGGSSGGGG 780 R P D T A G P P G G Q P PG PP GG G G G Sbjct: 559 LRGLPGKDGETGAAGPPGPAGPAGERGEQGAPGPSGFQGLPGPPGPPGEGGKPGDQGVPG 618 Query: 781 GGGAY----PPQPDFQPSQRTSASKLGALSLGSFNKPSSKDNLFGQSCLAALSTACQNMI 836 GA P P +R S G D G S A A Q Sbjct: 619 EAGAPGLVGPRGERGFPGERGSPGAQGLQGPRGLPGTPGTDGPKGASGPAGPPGA-QGPP 677 Query: 837 ASLGAPNLNVTFNKKNPPEGKRKLSQNETDGAAVAGNPGSDYFPGGTAP-GAPGPGGPSG 895 G P P + + + +GA PG D G T P G PGP G +G Sbjct: 678 GLQGMPGERGAAGIAGPKGDRGDVGEKGPEGA-----PGKDGGRGLTGPIGPPGPAGANG 732 Query: 896 TSSSGSKASGPPNP---------PAQGDGTSLSPNYTLESTSGNDGKPVSGGGGRGRGRR 946 GPP P P + T G DG+P G +G + Sbjct: 733 EKGE----VGPPGPAGSAGARGAPGERGETGPPGPAGFAGPPGADGQP-GAKGEQGEAGQ 787 Query: 947 KRDSGHVSPGTFFDKYSAAPDSGGAPGVSPGQQQASGA-----AVGGSSAGETRGAP--- 998 K D+G P S AP G GV+ G + A GA A G A G P Sbjct: 788 KGDAGAPGP----QGPSGAPGPQGPTGVT-GPKGARGAQGPPGATGFPGAAGRVGPPGSN 842 Query: 999 -TPHEKALTSPSWGKGAELLLGDQPDLIGSLDGGAKSDSSSPNVGEFASDEVSTSYANED 1057 P PS G + GD G + P + A +D Sbjct: 843 GNPGPPGPPGPSGKDGPKGARGDS---------GPPGRAGEPGLQGPAGPPGEKGEPGDD 893 Query: 1058 EVSSSSDNPQALVKASRSPLV--------TGSPKLP-----PRGVGA----GEHGPKAPP 1100 S + P A + +V G P LP P GA G+ GP P Sbjct: 894 GPSGAEGPPGPQGLAGQRGIVGLPGQRGERGFPGLPGPSGEPGKQGAPGASGDRGPPGPV 953 Query: 1101 PALGLGIMSNSTSTPDSYGGGGGPGHPGTPGLEQVRTPTSSSGAP----PPDEIHPLEIL 1156 GL + S G G PG G G++ R T + GAP PP P Sbjct: 954 GPPGLTGPAGEPGREGSPGADGPPGRDGAAGVKGDRGETGAVGAPGAPGPPGSPGP---- 1009 Query: 1157 QAQIQLQRQQFSISEDQPLGLKGGKKGECAVGASGAQNGDSELGSCCSEAVKSAMSTIDL 1216 Q + P+G G G G + E G +K L Sbjct: 1010 AGPTGKQGDRGEAGAQGPMGPSGPAGARGIQGPQGPRGDKGEAGEPGERGLKGHRGFTGL 1069 Query: 1217 DSL 1219 L Sbjct: 1070 QGL 1072 Score = 83.2 bits (204), Expect = 2e-15 Identities = 165/635 (25%), Positives = 199/635 (31%), Gaps = 130/635 (20%) Query: 564 RNQQQRLRQPN-LAQLGHPGDVGQ--GGLVHGGPVGGLAQPNFEREGGSTGAGRLGTFEQ 620 R Q Q +RQP Q G PGD+ G GP G + + G G E+ Sbjct: 22 RCQGQDVRQPGPKGQKGEPGDIKDIVGPKGPPGPQGPAGEQGPRGDRGDKG-------EK 74 Query: 621 QAPHLAQESAWFSGPHPPPGDLLPRRMGGSGLPADCGPHDPSLAPPPPPG---------- 670 AP GP R G G P + GP P PP PPG Sbjct: 75 GAP----------GPRG--------RDGEPGTPGNPGPPGPP-GPPGPPGLGGNFAAQMA 115 Query: 671 -----GSGVLFRGPLQEPMRMPGEGHVPA-LPSPGLQ-------------FGGSLGGLGQ 711 +G G +Q PM G P +PG Q G +G G Sbjct: 116 GGFDEKAGGAQLGVMQGPMGPMGPRGPPGPAGAPGPQGFQGNPGEPGEPGVSGPMGPRGP 175 Query: 712 LQSPG-----AGVGLPSAASERRPPPPDFATSALGGQPGFPFGAAGRQSTP--HSGPGVN 764 PG G P A ER PP P A G PG P G G + P G Sbjct: 176 PGPPGKPGDDGEAGKPGKAGERGPPGPQGA-RGFPGTPGLP-GVKGHRGYPGLDGAKGEA 233 Query: 765 SPPSAGGGGGSSGGGGGGGAYPPQPDFQPSQRTSASKLGALSLGSFN---KPSSKDNLFG 821 P G GS G G G P P P +R GA + P+ G Sbjct: 234 GAPGVKGESGSPGENGSPG--PMGPRGLPGERGRTGPAGAAGARGNDGQPGPAGPPGPVG 291 Query: 822 QSCLAALSTACQNMIASLGAPNLNVTFNKKNPPEGKRKLSQNETDG----AAVAGNPGSD 877 + + GA + P + + T G A +GNPG+D Sbjct: 292 PA-------GGPGFPGAPGAKGEAGPTGARGPEGAQGPRGEPGTPGSPGPAGASGNPGTD 344 Query: 878 YFPGGT-APGAPGPGGPSGTSSSGSKASGPPNPPAQGDGTSLSPNYTLESTSGNDGKPVS 936 PG + GAPG G G GPP P QG L P G G+P Sbjct: 345 GIPGAKGSAGAPGIAGAPGFPG----PRGPPGP--QGATGPLGP-------KGQTGEP-G 390 Query: 937 GGGGRGRGRRKRDSGHVSPGTFFDKYSAAPDSGGAPGVSPGQQQASGAAVGGSSAGETRG 996 G +G K + G P AP G G + + G VG RG Sbjct: 391 IAGFKGEQGPKGEPGPAGP-------QGAPGPAGEEGKRGARGEPGG--VGPIGPPGERG 441 Query: 997 AP----TPHEKALTSPSWGKGAELLLGDQPDLIGSLDGGAKSDSSSPNVGEFASDEVSTS 1052 AP P + L P G G L G GA D P E Sbjct: 442 APGNRGFPGQDGLAGPKGAPGERGPSG----LAG--PKGANGDPGRPG-------EPGLP 488 Query: 1053 YANEDEVSSSSDNPQALVKASRSPLVTGSPKLPPRGVGAGEHGPKAPPPALGLGIMSNST 1112 A PQ V S +P G P P G G + P +G + Sbjct: 489 GARGLTGRPGDAGPQGKVGPSGAPGEDGRPGPP------GPQGARGQPGVMGFPGPKGAN 542 Query: 1113 STPDSYGGGGGPGHPGTPGLEQVRTPTSSSGAPPP 1147 P G G PG PG GL T ++G P P Sbjct: 543 GEPGKAGEKGLPGAPGLRGLPGKDGETGAAGPPGP 577 Score = 60.5 bits (145), Expect = 1e-08 Identities = 110/459 (23%), Positives = 139/459 (30%), Gaps = 87/459 (18%) Query: 712 LQSPGAGVGLPSAASERRPPPPDFATSALGGQPGFPFGAAGRQSTPHSGPGVNSPPSAGG 771 L+ G V P ++ P G PG P G AG Q P G A G Sbjct: 21 LRCQGQDVRQPGPKGQKGEPGDIKDIVGPKGPPG-PQGPAGEQG-PRGDRGDKGEKGAPG 78 Query: 772 GGGSSG-GGGGGGAYPPQPDFQPSQRTSASKLGALSLGSFNKPSSKDNLFGQSCLAALST 830 G G G G PP P P A G F++ + A Sbjct: 79 PRGRDGEPGTPGNPGPPGPPGPPGPPGLGGNFAAQMAGGFDEKAG----------GAQLG 128 Query: 831 ACQNMIASLGAPNLNVTFNKKNPPEGKRKLSQNETDGAAVAGNPGSDYFPGGTA-PGAPG 889 Q + +G + PP AG PG F G PG PG Sbjct: 129 VMQGPMGPMG---------PRGPP--------------GPAGAPGPQGFQGNPGEPGEPG 165 Query: 890 PGGPSGTSSSGSKASGPPNPPAQ-GDGTSLSPNYTLESTSGNDGKPVSGGGGRGRGRRKR 948 GP G GPP PP + GD + +G GK G +G R Sbjct: 166 VSGPMG-------PRGPPGPPGKPGD----------DGEAGKPGKAGERGPPGPQGARGF 208 Query: 949 DSGHVSPGTFFDKYSAAPDSGGAPGVSPGQQQASGAAVGGSSAGETRGAPTPHEKALTSP 1008 PG + D +PG + SG+ S G P E+ T P Sbjct: 209 PGTPGLPGVKGHRGYPGLDGAKGEAGAPGVKGESGSPGENGSPGPMGPRGLPGERGRTGP 268 Query: 1009 SWGKGAELLLGD-----QPDLIGSLDG-------GAKSDSS-----SPNVGEFASDEVST 1051 + GA G P +G G GAK ++ P + E T Sbjct: 269 AGAAGARGNDGQPGPAGPPGPVGPAGGPGFPGAPGAKGEAGPTGARGPEGAQGPRGEPGT 328 Query: 1052 SYANEDEVSSSSDNPQALVKASRS---PLVTGSPKLPPRGVGAGEHGPKAPPPALGLGIM 1108 + +S + + A S P + G+P P G GP P A G Sbjct: 329 PGSPGPAGASGNPGTDGIPGAKGSAGAPGIAGAPGFP------GPRGPPGPQGATGPLGP 382 Query: 1109 SNSTSTPDSYGGGGGPGHPGTPGLEQVRTPTSSSGAPPP 1147 T P G G G G PG P GAP P Sbjct: 383 KGQTGEPGIAGFKGEQGPKGEPG------PAGPQGAPGP 415 Score = 38.1 bits (87), Expect = 0.056 Identities = 82/315 (26%), Positives = 107/315 (33%), Gaps = 65/315 (20%) Query: 888 PGPGGPSGTSSSGSKASGPPNPPA-QGDGTSLSPNYTLESTSGNDGKPVSGGGGRGRGRR 946 PGP G G GP PP QG P G G P G R Sbjct: 31 PGPKGQKGEPGDIKDIVGPKGPPGPQGPAGEQGPRGD-RGDKGEKGAP---------GPR 80 Query: 947 KRDSGHVSPGTFFDKYSAAPDSGGAPGVSPGQQQASGAAVGGSSAGETRGAPTPHEKALT 1006 RD PGT P + G PG PG G +GG+ A + G EKA Sbjct: 81 GRDG---EPGT--------PGNPGPPG-PPGPPGPPG--LGGNFAAQMAGGFD--EKA-- 122 Query: 1007 SPSWGKGAELLLGDQPDLIGSLDG-GAKSDSSSPNVGEFASDEVSTSYANEDEVSSSSDN 1065 GA+L + P +G + G + +P F + E VS Sbjct: 123 -----GGAQLGVMQGP--MGPMGPRGPPGPAGAPGPQGFQGNP---GEPGEPGVSGPM-G 171 Query: 1066 PQALVKASRSPLVTGSPKLPPRGVGAGEHGPKAPPPALGLGIMSNSTSTPDSYGGGGGPG 1125 P+ P G P + AGE GP P A G P + G G G Sbjct: 172 PRGPPGPPGKPGDDGEAGKPGK---AGERGPPGPQGARGF---------PGTPGLPGVKG 219 Query: 1126 HPGTPGLEQVRTPTSSSGAPPPDEIHPLEILQAQIQLQRQQFSISEDQPLGLKGGKKGEC 1185 H G PGL+ + +GAP ++ + + S P GL G + Sbjct: 220 HRGYPGLDGAK---GEAGAPG---------VKGESGSPGENGSPGPMGPRGLPGERGRTG 267 Query: 1186 AVGASGAQNGDSELG 1200 GA+GA+ D + G Sbjct: 268 PAGAAGARGNDGQPG 282 >gi|111118972 collagen, type XI, alpha 2 isoform 2 preproprotein [Homo sapiens] Length = 1650 Score = 97.1 bits (240), Expect = 1e-19 Identities = 152/603 (25%), Positives = 193/603 (32%), Gaps = 58/603 (9%) Query: 571 RQPNLAQLGHPGDVGQGGLVHGGPVGGLAQPNFEREGGSTGA-GRLGTFEQQAPHLAQES 629 RQ LG PG G G + G + P ER G TG G+ G A+ + Sbjct: 720 RQGPKGSLGFPGFPGASGEKGARGLSGKSGPRGER--GPTGPRGQRGPRGATGKSGAKGT 777 Query: 630 AWFSGPHPPPGDL-LPRRMGGSGLPADCGPHDPSLAPPPPPGGSGVLFRGPLQEPMRMPG 688 + GPH PPG+ LP G +G P GP P PPG G+ + + G Sbjct: 778 SGGDGPHGPPGERGLPGPQGPNGFPGPKGP-------PGPPGKDGLPGHPGQRGEVGFQG 830 Query: 689 EGHVPALPSPGLQFG--GSLGGLGQLQSPGAGVGLPSAASERRPPPPDFATSALGGQPGF 746 + P P G G G +G+ PG P + P G PG Sbjct: 831 KTGPPGPPGVVGPQGAAGETGPMGERGHPG-----PPGPPGEQGLPGTAGKEGTKGDPGP 885 Query: 747 PFGAAGRQSTP--HSGPGVNSPPSAGGGGGSSGGGGGGGAYPPQPDFQPSQRTSASKLGA 804 P GA G+ PG P GG G G G G PP P P +R +A G Sbjct: 886 P-GAPGKDGPAGLRGFPGERGLPGTAGGPGLKGNEGPSG--PPGPAGSPGERGAAGSGGP 942 Query: 805 LSLGSFNKPSSKDNLFGQSCLAALS-----TACQNMIASLGAPNLNVTFNKKNPPEGKRK 859 + P G+ + T + +G P P G Sbjct: 943 IGPPGRPGPQGPPGAAGEKGVPGEKGPIGPTGRDGVQGPVGLPG----------PAGPPG 992 Query: 860 LSQNETDGAAVAGNPGSDYFPGGTAP-GAPGPGGPSGTSSSGSKASGPPNPPAQGDGTSL 918 ++ + D V G+PG G G PGP GP G A P A+G Sbjct: 993 VAGEDGDKGEV-GDPGQKGTKGNKGEHGPPGPPGPIGPVGQPGAAGADGEPGARGPQGHF 1051 Query: 919 SPNYTLESTSGNDGKPVSGG--GGRGRGRRKRDSGHVSP----GTFFDKYSAAPDSGGAP 972 E T G +G P G G G K ++G V P G + A P+ P Sbjct: 1052 GAKGD-EGTRGFNGPPGPIGLQGLPGPSGEKGETGDVGPMGPPGPPGPRGPAGPNGADGP 1110 Query: 973 GVSPGQQQASGAAVGGSSAGETRGAPTPHEKALTSPSWGKGAELLLGDQPDLIG--SLDG 1030 PG G GE+ E + P +G + G QP G G Sbjct: 1111 QGPPGGVGNLGPPGEKGEPGESGSPGIQGEPGVKGPRGERGEKGESG-QPGEPGPPGPKG 1169 Query: 1031 GAKSDSSSPNVGEFASDEVSTSYANEDEVSSSSDNPQALVKASRSPLVTGSPKLPPRGVG 1090 D N G D P+ A G P P Sbjct: 1170 PTGDDGPKGNPGPVGFPG--------DPGPPGEGGPRGQDGAKGDRGEDGEPGQPGSPGP 1221 Query: 1091 AGEHGPKAPPPALGLGIMSNSTSTPDSYGGGGGPGHPGTPGLEQVRTPTSSSGAPPPDEI 1150 GE+GP P G S G G PG G PG P +G P PD + Sbjct: 1222 TGENGPPGPLGKRGPAGSPGSEGRQGGKGAKGDPGAIGAPGKTGPVGPAGPAGKPGPDGL 1281 Query: 1151 HPL 1153 L Sbjct: 1282 RGL 1284 Score = 87.4 bits (215), Expect = 8e-17 Identities = 292/1162 (25%), Positives = 364/1162 (31%), Gaps = 265/1162 (22%) Query: 43 GPPGPVDPAMSALGEPPILGMNMEPYGFHARGHSELHAGGLQAQPVHGFFGGQQPHHGHP 102 GPPG A G GM +P RG L GL + H G Q G P Sbjct: 443 GPPGKAGRRGRA-GADGARGMPGDPGVKGDRGFDGLP--GLPGEKGHRGDTGAQGLPGPP 499 Query: 103 GSHHPHQHHPHFGGNFGGPDPGASCLHGGRLLGYGGAAGGLGSQPPFAEGYEHMAESQGP 162 G G PG S G LLG G G G PP G M QGP Sbjct: 500 GEDGERGDDGEIGPR---GLPGESGPRG--LLGPKGPPGIPG--PPGVRG---MDGPQGP 549 Query: 163 E-SFGPQ-RPGNLPDFHSSGASSHAVPAPCLPL----DQSPNRAASFHGLPSSSGSDSHS 216 + S GPQ PG P + +P P + ++ P G+P S G H Sbjct: 550 KGSLGPQGEPG--PPGQQGTPGTQGLPGPQGAIGPHGEKGPQGKPGLPGMPGSDGPPGH- 606 Query: 217 LEPRRVTNQGAVDSLEYNYPG-EAPSGHFDMFSPSDSEGQLPHYAAGRQVPGGAFPGASA 275 PG E P G PS +G L +PG Sbjct: 607 -------------------PGKEGPPGTKGNQGPSGPQGPL------------GYPGPRG 635 Query: 276 MPRAAGMVGLSKMHAQPPQQQPQQQQQPQQQQQQHGVFFERFSGARKMPVGLEPSVGSRH 335 + G+ GL K H + ++ + G F F G +G++ G R Sbjct: 636 VKGVDGIRGL-KGH--------------KGEKGEDG--FPGFKG----DIGVK---GDRG 671 Query: 336 PLMQPPQQAPPPPQQQPPQQPPQQQPPPPPGLLVRQNSCPPALPRPQQGEAGTPSGGLQD 395 + P + P+ + P P PP + + P LP G G P G L Sbjct: 672 EVGVPGSRGEDGPEGPKGRTGPTGDPGPPGLMGEKGKLGVPGLPG-YPGRQG-PKGSL-- 727 Query: 396 GGPMLPSQHAQFEYPIHRLENRSMHPYSEPVFSMQHPPPQQAPNQRLQHFDAPPYMNVAK 455 G P P A E L +S P ++ P Sbjct: 728 GFPGFPG--ASGEKGARGLSGKS------------GPRGERGPTG--------------- 758 Query: 456 RPRFDFPGSAGVDRCASWNGSMHNGALDNHLSPSAYPGLPGEFTPPVPDSFPS-----GP 510 PR G G +G+ D P GLPG P P+ FP GP Sbjct: 759 -PR----GQRGPRGATGKSGAKGTSGGDGPHGPPGERGLPG---PQGPNGFPGPKGPPGP 810 Query: 511 PLQHPAPDHQSLQQQQQQQQQQQQQQQQQQQQQQQQQQQQRQNAALMIKQMASRNQQQRL 570 P + P H Q+ + Q + Q AA M R Sbjct: 811 PGKDGLPGHPG--------QRGEVGFQGKTGPPGPPGVVGPQGAAGETGPMGERGHPGPP 862 Query: 571 RQPNLAQLGHPGDVGQGGLVHG-GPVGGLAQPN------FEREGGSTG-AGRLGTFEQQA 622 P + G PG G+ G GP G + F E G G AG G + Sbjct: 863 GPPG--EQGLPGTAGKEGTKGDPGPPGAPGKDGPAGLRGFPGERGLPGTAGGPGLKGNEG 920 Query: 623 PHLAQESAWFSGPHPPPGDLLPRRMGGSGLPADCGPHDPSLAPPP--PPGGSGVLF---- 676 P SGP P G R GSG GP P P P PPG +G Sbjct: 921 P---------SGPPGPAGSPGERGAAGSG-----GPIGPPGRPGPQGPPGAAGEKGVPGE 966 Query: 677 RGPL--------QEPMRMPGEGHVPALPSPGLQFGGSLGGLGQLQSPGAGVGLPSAASER 728 +GP+ Q P+ +PG PA P PG+ G G G++ PG G E Sbjct: 967 KGPIGPTGRDGVQGPVGLPG----PAGP-PGV--AGEDGDKGEVGDPGQK-GTKGNKGEH 1018 Query: 729 RPPPPDFATSALG--------GQPGFP-----FGAAGRQSTPHSGPGVNSPPSAGGGGGS 775 PP P +G G+PG FGA G + T G N PP G G Sbjct: 1019 GPPGPPGPIGPVGQPGAAGADGEPGARGPQGHFGAKGDEGTR----GFNGPPGPIGLQGL 1074 Query: 776 SGGGGG----GGAYPPQPDFQPSQRTSASKLGALS-------LGSFNKPSSKDNLFGQSC 824 G G G P P P R A GA +G+ P K G+S Sbjct: 1075 PGPSGEKGETGDVGPMGPPGPPGPRGPAGPNGADGPQGPPGGVGNLGPPGEKGEP-GESG 1133 Query: 825 LAALS--TACQNMIASLGAPNLNVTFNKKNPPEGKRKLSQNETDGAAVAGNPGSDYFPGG 882 + + G + + PP K T GNPG FPG Sbjct: 1134 SPGIQGEPGVKGPRGERGEKGESGQPGEPGPPGPK-----GPTGDDGPKGNPGPVGFPGD 1188 Query: 883 TAPGAPGPGGPSGTSSS-GSKAS-GPPNPPAQGDGTSLSPNYTLESTSGNDGKPVSGGGG 940 PG PG GGP G + G + G P P T + G G P S G Sbjct: 1189 --PGPPGEGGPRGQDGAKGDRGEDGEPGQPGSPGPTGENGPPGPLGKRGPAGSPGSEGRQ 1246 Query: 941 RGRGRRKRDSGHVSPGTFFDKYSAAPDSG-------GAPGVSPGQQQASGAAVGGSSAGE 993 G+G + +PG A P G PG S GQQ GA AG Sbjct: 1247 GGKGAKGDPGAIGAPGKTGPVGPAGPAGKPGPDGLRGLPG-SVGQQGRPGAT---GQAGP 1302 Query: 994 TRGAPTPHEKALTSPSWGKGAELLLGDQPDLIGSL----DGGAKSDSSSPNVGEFASDEV 1049 P L + KG + P LIG + + G K D P Sbjct: 1303 PGPVGPPGLPGLRGDAGAKGEK----GHPGLIGLIGPPGEQGEKGDRGLPG--------- 1349 Query: 1050 STSYANEDEVSSSSDNPQALVKASRSPLVTGSPKLPPRGVGAGEHGPKAPPPALGLGIMS 1109 S + + + P+ G P P G GPK A G G Sbjct: 1350 --------PQGSPGQKGEMGIPGASGPIGPGGPPGLP-----GPAGPKGAKGATGPG--- 1393 Query: 1110 NSTSTPDSYGGGGGPGHPGTPG 1131 G G PGHPG PG Sbjct: 1394 ---GPKGEKGVQGPPGHPGPPG 1412 Score = 87.0 bits (214), Expect = 1e-16 Identities = 237/941 (25%), Positives = 301/941 (31%), Gaps = 176/941 (18%) Query: 327 LEPSVGSRH-PLMQPPQQAPPPPQQQPP-------QQPPQQQPPPPPGLLVRQNSCPPAL 378 LE G R P Q P +A PQQQP Q+P Q P P + ++S P L Sbjct: 226 LECEGGQRERPQNQQPHRAQRSPQQQPSRLHRPQNQEPQSQDPTPGEEEEILESSLLPPL 285 Query: 379 ------PRPQQGEAGTPS---GGLQDGGPMLPSQHAQFEYPIHRLENRSMHPYSEPVFSM 429 PR +GE G P+ G+ GP P A P N P +P Sbjct: 286 EEAAHGPRGLKGEKGEPAVLEPGMLVEGPPGPEGPAGLIGPPGIQGNPG--PVGDP---G 340 Query: 430 QHPPPQQAPNQRLQHFDAPPYMNVAKRPRFDFPGSAGVDR---CASWNGSMHNGALDNHL 486 + PP +A PP ++ RF GS G D+ A+ L Sbjct: 341 ERGPPGRAGLPGSDGAPGPPGTSLMLPFRF---GSGGGDKGPVVAAQEAQAQAILQQARL 397 Query: 487 SPSAYPGLPGEFTPPVPDSFPSGPPLQHPAPDHQSLQQQQQQQQQQQQQQQQQQQQQQQQ 546 + PG G P P P P L+ + D Q + Q + ++ Sbjct: 398 ALRGPPGPMGYTGRPGPLGQPGSPGLKGESGD------LGPQGPRGPQGLTGPPGKAGRR 451 Query: 547 QQQQRQNAALMIKQMASRNQQQRLRQPNL-AQLGHPGDVGQGGLVHGGPVGGLAQPNFER 605 + A M + + P L + GH GD G GL GP G + + Sbjct: 452 GRAGADGARGMPGDPGVKGDRGFDGLPGLPGEKGHRGDTGAQGL--PGPPGEDGERGDDG 509 Query: 606 EGGSTG----AGRLGTFEQQAPHLAQES---AWFSGPHPPPGDLLPR----------RMG 648 E G G +G G + P GP P G L P+ G Sbjct: 510 EIGPRGLPGESGPRGLLGPKGPPGIPGPPGVRGMDGPQGPKGSLGPQGEPGPPGQQGTPG 569 Query: 649 GSGLPAD---CGPHD-------------PSLAPPP-------PPGGSGVLFRGPLQEPMR 685 GLP GPH P PP PPG G Q P+ Sbjct: 570 TQGLPGPQGAIGPHGEKGPQGKPGLPGMPGSDGPPGHPGKEGPPGTKGNQGPSGPQGPLG 629 Query: 686 MPG-------------EGHVPALPSPGLQFGGSLGGLGQLQSPGAGVGLPSAASERRPPP 732 PG +GH G F G G +G ++ VG+P + E P Sbjct: 630 YPGPRGVKGVDGIRGLKGHKGEKGEDG--FPGFKGDIG-VKGDRGEVGVPGSRGEDGPEG 686 Query: 733 PDFATSALG--------------GQPGFPFGAAGRQSTPHS-----GPGVNSPPSAGGGG 773 P T G G PG P G GRQ S PG + A G Sbjct: 687 PKGRTGPTGDPGPPGLMGEKGKLGVPGLP-GYPGRQGPKGSLGFPGFPGASGEKGARGLS 745 Query: 774 GSSGGGGGGGAYPPQPDFQPSQRTSASKLGALSLGSFNKPSSKDNLFGQSCLAALSTACQ 833 G SG G G P P Q R + K GA + P G Sbjct: 746 GKSGPRGERG--PTGPRGQRGPRGATGKSGAKGTSGGDGPHGPPGERGLP---------- 793 Query: 834 NMIASLGAPNLNVTFNKKNPPEGKRKLSQNETDGAAVAGNPGSD---YFPGGTA-PGAPG 889 G N K PP K DG + G+PG F G T PG PG Sbjct: 794 ------GPQGPNGFPGPKGPPGPPGK------DG--LPGHPGQRGEVGFQGKTGPPGPPG 839 Query: 890 PGGPSG----TSSSGSKA-SGPPNPPAQGDGTSLSPNYTLESTSGNDGKPVSGGGGRGRG 944 GP G T G + GPP PP + L E T G+ G P + G G Sbjct: 840 VVGPQGAAGETGPMGERGHPGPPGPPGE---QGLPGTAGKEGTKGDPGPPGAPGKDGPAG 896 Query: 945 RRKRDSGHVSPGTFFD---KYSAAPDSGGAPGVSPGQQQA--SGAAVGGSSAGETRGAP- 998 R PGT K + P P SPG++ A SG +G +G P Sbjct: 897 LRGFPGERGLPGTAGGPGLKGNEGPSGPPGPAGSPGERGAAGSGGPIGPPGRPGPQGPPG 956 Query: 999 ------TPHEKALTSPSWGKGAELLLGDQPDLIGSLDGGAKSDSSSPNVGEFASDEVSTS 1052 P EK P+ G + +G P G G A D VG+ + T Sbjct: 957 AAGEKGVPGEKGPIGPTGRDGVQGPVG-LPGPAGP-PGVAGEDGDKGEVGD--PGQKGTK 1012 Query: 1053 YANEDEVSSSSDNPQALVKASRSPLVTGSP--KLPPRGVGA----GEHGPKAPPPALGLG 1106 + P V + G P + P GA G G PP +GL Sbjct: 1013 GNKGEHGPPGPPGPIGPVGQPGAAGADGEPGARGPQGHFGAKGDEGTRGFNGPPGPIGLQ 1072 Query: 1107 IMSNSTSTPDSYGGGGGPGHPGTPGLEQVRTPTSSSGAPPP 1147 + + G G G PG PG R P +GA P Sbjct: 1073 GLPGPSGEKGETGDVGPMGPPGPPG---PRGPAGPNGADGP 1110 Score = 85.5 bits (210), Expect = 3e-16 Identities = 159/615 (25%), Positives = 192/615 (31%), Gaps = 116/615 (18%) Query: 579 GHPGDVG-QGGLVHGGPVGGLAQPNFEREGGSTG----AGRLGTFEQQAPHLAQESAWFS 633 G PG VG QG GP+G P G G AG+ GT P A + Sbjct: 836 GPPGVVGPQGAAGETGPMGERGHPGPPGPPGEQGLPGTAGKEGTKGDPGPPGAPGKDGPA 895 Query: 634 GPHPPPGDL-LPRRMGGSGLPADCGPHDPSLAPPPPPGGSGVLFRG-PLQEPMRMPGEGH 691 G PG+ LP GG GL + GP P P PG G G P+ P R +G Sbjct: 896 GLRGFPGERGLPGTAGGPGLKGNEGPSGPP-GPAGSPGERGAAGSGGPIGPPGRPGPQGP 954 Query: 692 VPALPSPGLQFGGSLGGLGQLQSPGAG--VGLPSAASERRPPPPDFATSALGGQPGFPFG 749 A G+ G G +G G VGLP A PP G+ G P G Sbjct: 955 PGAAGEKGVP--GEKGPIGPTGRDGVQGPVGLPGPAG----PPGVAGEDGDKGEVGDP-G 1007 Query: 750 AAGRQSTP--HSGPGVNSPPSAGGGGGSSGGGGGGGAYPPQPDF----QPSQRTSASKLG 803 G + H PG P G G++G G GA PQ F R G Sbjct: 1008 QKGTKGNKGEHGPPGPPGPIGPVGQPGAAGADGEPGARGPQGHFGAKGDEGTRGFNGPPG 1067 Query: 804 ALSLGSFNKPSSKDNLFGQSCLAALSTACQNMIASLGAPNLNVTFNKKNPPEGKRKLSQN 863 + L PS + G + +G P PP + N Sbjct: 1068 PIGLQGLPGPSGEKGETGD-------------VGPMGPPG---------PPGPRGPAGPN 1105 Query: 864 ETDGA-------------AVAGNPGSDYFPGGTA-PGAPGPGGPSGTSSSGSKAS--GPP 907 DG G PG PG PG GP G G + GPP Sbjct: 1106 GADGPQGPPGGVGNLGPPGEKGEPGESGSPGIQGEPGVKGPRGERGEKGESGQPGEPGPP 1165 Query: 908 NP--PAQGDGTSLSPNYTLESTSGNDGKPVSGGGGRGRGRRKRDSGHV-------SPGTF 958 P P DG +P G+ G P GG RG+ K D G SPG Sbjct: 1166 GPKGPTGDDGPKGNPGPV--GFPGDPGPP-GEGGPRGQDGAKGDRGEDGEPGQPGSPGPT 1222 Query: 959 FDKYSAAPDSGGAPGVSPGQQQASGAAVGGSSAGETRGAPTPHEKALTSPSWGKGAELLL 1018 + P P SPG + G G + G+ P + P+ G Sbjct: 1223 GENGPPGPLGKRGPAGSPGSEGRQG---GKGAKGDPGAIGAPGKTGPVGPAGPAGKP--- 1276 Query: 1019 GDQPDLIGSLDGGAKSDSSSPNVGEFASDEVSTSYANEDEVSSSSDNPQALVKASRSPLV 1078 PD + L G +VG+ P A +A P Sbjct: 1277 --GPDGLRGLPG---------SVGQ-------------------QGRPGATGQAG-PPGP 1305 Query: 1079 TGSPKLPPRGVGAGEHGPKAPPPALGL------GIMSNSTSTPDSYGGGGGPGHPGTPGL 1132 G P LP AG G K P +GL P G G G G PG Sbjct: 1306 VGPPGLPGLRGDAGAKGEKGHPGLIGLIGPPGEQGEKGDRGLPGPQGSPGQKGEMGIPGA 1365 Query: 1133 EQVRTPTSSSGAPPP 1147 P G P P Sbjct: 1366 SGPIGPGGPPGLPGP 1380 Score = 79.7 bits (195), Expect = 2e-14 Identities = 246/1018 (24%), Positives = 319/1018 (31%), Gaps = 205/1018 (20%) Query: 82 GLQAQP-VHGFFGGQQPHHGHPGSHHPHQHHPHFGGNFGGPDPGASCLHGGRLLGYGGAA 140 G+ P V G G Q P GS P Q P G G PG L G + GA Sbjct: 533 GIPGPPGVRGMDGPQGPK----GSLGP-QGEPGPPGQQG--TPGTQGLPGPQ-----GAI 580 Query: 141 GGLGSQPPFAE-GYEHMAESQGPESFGPQRPGNLPDFHSSGASSHAVPAPCL--PLDQSP 197 G G + P + G M S GP P PG + G + P L P + Sbjct: 581 GPHGEKGPQGKPGLPGMPGSDGP----PGHPGKEGPPGTKGNQGPSGPQGPLGYPGPRGV 636 Query: 198 NRAASFHGLPSSSGSDSHSLEPRRVTNQGAV-DSLEYNYPG----EAPSGHFDMFSPSDS 252 GL G P + G D E PG + P G P+ Sbjct: 637 KGVDGIRGLKGHKGEKGEDGFPGFKGDIGVKGDRGEVGVPGSRGEDGPEGPKGRTGPTGD 696 Query: 253 EGQ--------------LPHYAAGRQVPGGA-----FPGASAMPRAAGMVGLSKMHAQPP 293 G LP Y GRQ P G+ FPGAS A G+ G S + Sbjct: 697 PGPPGLMGEKGKLGVPGLPGYP-GRQGPKGSLGFPGFPGASGEKGARGLSGKSGPRGERG 755 Query: 294 QQQPQQQQQPQQQQQQHGVFFERFSGARKMPVGLEPSVGSRHPLMQPPQQAPPPPQQQP- 352 P+ Q+ P+ + G P G G + P P + PP P + Sbjct: 756 PTGPRGQRGPRGATGKSGAKGTSGGDGPHGPPGERGLPGPQGPNGFPGPKGPPGPPGKDG 815 Query: 353 -PQQPPQQQ---------PPPPPGLLVRQNSCPPALPRPQQGEAGTPSGGLQDGGPMLPS 402 P P Q+ PP PPG++ Q + P ++G G P + G P Sbjct: 816 LPGHPGQRGEVGFQGKTGPPGPPGVVGPQGAAGETGPMGERGHPGPPGPPGEQGLPGTAG 875 Query: 403 QHAQFEYPIHRLENRSMHPYSEPVFSMQHPPPQQAPNQRLQHFDAPPYMNVAKRPRFDFP 462 + + P P AP + D P + FP Sbjct: 876 KEG----------------------TKGDPGPPGAPGK-----DGPAGLR-------GFP 901 Query: 463 GSAGVDRCASWNGSMHNGALDNHLSPSAYPGLPGEFTPPVPDSFPSGPPLQHPA-PDHQS 521 G G+ A G L + PS PG G +P + SG P+ P P Q Sbjct: 902 GERGLPGTAGGPG------LKGNEGPSGPPGPAG--SPGERGAAGSGGPIGPPGRPGPQG 953 Query: 522 LQQQQQQQQQQQQQQQQQQQQQQQQQQQQRQNAALMIKQMASRNQQQRLRQPNLAQLGHP 581 ++ ++ + Q +A + + ++G P Sbjct: 954 PPGAAGEKGVPGEKGPIGPTGRDGVQGPVGLPGPAGPPGVAGEDGDK-------GEVGDP 1006 Query: 582 GDVGQGGLV--HG-----GPVGGLAQPNFEREGGSTGA-GRLGTFEQQAPHLAQESAWFS 633 G G G HG GP+G + QP G GA G G F + + + F+ Sbjct: 1007 GQKGTKGNKGEHGPPGPPGPIGPVGQPGAAGADGEPGARGPQGHFGAKGD---EGTRGFN 1063 Query: 634 GPHPPPG-DLLPRRMGGSGLPADCGPHDPSLAPPP--------------PPGGSGVLFRG 678 GP P G LP G G D GP P P P PPGG G L G Sbjct: 1064 GPPGPIGLQGLPGPSGEKGETGDVGPMGPPGPPGPRGPAGPNGADGPQGPPGGVGNL--G 1121 Query: 679 PLQEPMRMPGEGHVPALPS-PGLQFG----GSLGGLGQLQSPGAG--------------- 718 P E PGE P + PG++ G G GQ PG Sbjct: 1122 PPGEKGE-PGESGSPGIQGEPGVKGPRGERGEKGESGQPGEPGPPGPKGPTGDDGPKGNP 1180 Query: 719 -----VGLPSAASERRPPPPDFATSALG-----GQPGFP-----------FGAAGRQSTP 757 G P E P D A G GQPG P G G +P Sbjct: 1181 GPVGFPGDPGPPGEGGPRGQDGAKGDRGEDGEPGQPGSPGPTGENGPPGPLGKRGPAGSP 1240 Query: 758 HS-----GPGVNSPPSAGGGGGSSGG-GGGGGAYPPQPDFQ---PSQRTSASKLGALSLG 808 S G G P A G G +G G G A P PD P + GA Sbjct: 1241 GSEGRQGGKGAKGDPGAIGAPGKTGPVGPAGPAGKPGPDGLRGLPGSVGQQGRPGATGQA 1300 Query: 809 SFNKPSSKDNLFGQSCLAALS--TACQNMIASLGAPNLNVTFNKKNPPEGKRKLSQNETD 866 P L G A +I +G P + P + Q Sbjct: 1301 GPPGPVGPPGLPGLRGDAGAKGEKGHPGLIGLIGPPGEQGEKGDRGLPGPQGSPGQKGEM 1360 Query: 867 GAAVAGNPGSDYFPGGTAPGAPGPGGPSGTSSSGSKASGPPNPPAQGDGTSLSPNYTLES 926 G A P PGG PG PGP GP G A+GP P + ++ Sbjct: 1361 GIPGASGPIG---PGGP-PGLPGPAGPKGAKG----ATGPGGPKGEKG---------VQG 1403 Query: 927 TSGNDGKPVSGGGGRGRGRRKRDSGHVSPGTFFDKYSAAPDSGGAPGVSPGQQQASGA 984 G+ G P K+ V + A P +GGAPG G ++ G+ Sbjct: 1404 PPGHPGPPGEVIQPLPIQMPKKTRRSVDGSRLMQEDEAIP-TGGAPGSPGGLEEIFGS 1460 Score = 70.9 bits (172), Expect = 8e-12 Identities = 175/740 (23%), Positives = 232/740 (31%), Gaps = 151/740 (20%) Query: 510 PPLQHPAPDHQSLQQQQQQQQQQQQQQQQQQQQQQQQQQQQRQNAALMIKQMASRNQ--- 566 P Q P +S QQQ + + Q Q+ Q Q ++++ +++ L + A+ Sbjct: 236 PQNQQPHRAQRSPQQQPSRLHRPQNQEPQSQDPTPGEEEEILESSLLPPLEEAAHGPRGL 295 Query: 567 -----QQRLRQPNLAQLGHPGDVGQGGLVHGGPVGGLAQPNFEREGGSTG-AGRLGTFEQ 620 + + +P + G PG G GL+ GP G P + G G GR G Sbjct: 296 KGEKGEPAVLEPGMLVEGPPGPEGPAGLI--GPPGIQGNPGPVGDPGERGPPGRAGL--- 350 Query: 621 QAPHLAQESAWFSGPHPPPGD--LLPRRMGGSGLPADCGP-------------HDPSLAP 665 G PPG +LP R G G D GP LA Sbjct: 351 ---------PGSDGAPGPPGTSLMLPFRFGSGG--GDKGPVVAAQEAQAQAILQQARLAL 399 Query: 666 PPPPGGSGVLFR-GPLQEPMRMPGEGHVPALPSPGLQ-FGGSLGGLGQLQSPGAGVGLPS 723 PPG G R GPL +P SPGL+ G LG G + P G P Sbjct: 400 RGPPGPMGYTGRPGPLGQP------------GSPGLKGESGDLGPQGP-RGPQGLTGPPG 446 Query: 724 AASERRPPPPDFATSALGGQPGFPFGAAGRQSTPHSGPGVNSPPSAGGGGGSSGGGGGGG 783 A R D A G PG P G G + G + P G G G G G Sbjct: 447 KAGRRGRAGADGAR----GMPGDP-GVKGDR-------GFDGLPGLPGEKGHRGDTGAQG 494 Query: 784 AYPPQPDFQPSQRTSASKLGALSLGSFNKPSSKDNLFGQSCLAALSTACQNMIASLGAPN 843 P P + +R ++G L + P L G G P Sbjct: 495 L--PGPPGEDGERGDDGEIGPRGLPGESGPR---GLLGPK-------------GPPGIPG 536 Query: 844 LNVTFNKKNPPEGKRKLS-QNETDGAAVAGNPGSDYFPGGTAPGAPGPGGPSGTSSSGS- 901 P K L Q E G PG+ PG GA GP G G Sbjct: 537 PPGVRGMDGPQGPKGSLGPQGEPGPPGQQGTPGTQGLPG--PQGAIGPHGEKGPQGKPGL 594 Query: 902 ----KASGPPNPPAQGDGTSLSPNYTLESTSGNDGKPVSGG-----GGRGRGRRKRDSGH 952 + GPP P + N G G P G G RG K + G Sbjct: 595 PGMPGSDGPPGHPGKEGPPGTKGNQGPSGPQGPLGYPGPRGVKGVDGIRGLKGHKGEKGE 654 Query: 953 VSPGTFFDKYSAAPDSG--GAPGVSPGQQQASGAAVGGSSAGETRGAPTPHEKALTSPSW 1010 F D G G PG S G+ G K T P+ Sbjct: 655 DGFPGFKGDIGVKGDRGEVGVPG-SRGEDGPEG------------------PKGRTGPTG 695 Query: 1011 GKGAELLLGDQPDL-IGSLDG-----GAKSDSSSPNVGEFASDEVSTSYANEDEVSSSSD 1064 G L+G++ L + L G G K P + ++ + + + + Sbjct: 696 DPGPPGLMGEKGKLGVPGLPGYPGRQGPKGSLGFPGFPGASGEKGARGLSGKS--GPRGE 753 Query: 1065 NPQALVKASRSPL-VTGSPKLPPRGVGAGEHGP---KAPPPALGLGIMSNSTSTPDSYGG 1120 + R P TG G G HGP + P G P G Sbjct: 754 RGPTGPRGQRGPRGATGKSGAKGTSGGDGPHGPPGERGLPGPQGPNGFPGPKGPPGPPGK 813 Query: 1121 GGGPGHPGTPGLEQVRTPTSSSGAPPPDEIHPLEILQAQIQLQRQQFSISEDQPLGLKG- 1179 G PGHPG G + T G PP + P Q + E P+G +G Sbjct: 814 DGLPGHPGQRGEVGFQGKTGPPG--PPGVVGP-------------QGAAGETGPMGERGH 858 Query: 1180 ----GKKGECAVGASGAQNG 1195 G GE + + + G Sbjct: 859 PGPPGPPGEQGLPGTAGKEG 878 Score = 40.4 bits (93), Expect = 0.011 Identities = 97/381 (25%), Positives = 122/381 (32%), Gaps = 73/381 (19%) Query: 37 PAFHTGGPPGPVDPAMSALGEPPILGMNMEPYGFHARGHSELHAGGLQAQPVHGFFGGQQ 96 P GPPGP PA +G P I G N P G G + P G Sbjct: 307 PGMLVEGPPGPEGPA-GLIGPPGIQG-NPGPVG----------DPGERGPPGRAGLPGSD 354 Query: 97 PHHGHPGSHHPHQHHPHFGGNFGGPDPGA------SCLHGGRL--------LGYGGAAGG 142 G PG+ GG GP A + L RL +GY G G Sbjct: 355 GAPGPPGTSLMLPFRFGSGGGDKGPVVAAQEAQAQAILQQARLALRGPPGPMGYTGRPGP 414 Query: 143 LGSQP--PFAEGYEHMAESQGPESFGPQRPGNLPDFHSSGASSHAVPAPCLPLDQSPNRA 200 LG QP P +G QGP GPQ P + A A +P D Sbjct: 415 LG-QPGSPGLKGESGDLGPQGPR--GPQGLTGPPGKAGRRGRAGADGARGMPGDPGVKGD 471 Query: 201 ASFHGLPSSSGSDSHSLEPRRVTNQGAVDSLEYNYPGEAPSGHFDMFSPSDSEGQL-PHY 259 F GLP G H D+ PG P G +G++ P Sbjct: 472 RGFDGLPGLPGEKGH-----------RGDTGAQGLPG--PPGE---DGERGDDGEIGPRG 515 Query: 260 AAGRQVPGGAF--PGASAMPRAAGMVGLSKMHAQPPQQQPQQQQQPQQQQQQHGVFFERF 317 G P G G +P G+ G+ PQ + P QQ Sbjct: 516 LPGESGPRGLLGPKGPPGIPGPPGVRGMDGPQGPKGSLGPQGEPGPPGQQGT-------- 567 Query: 318 SGARKMPVGLEPSVGSRHPLMQPPQQAPPPPQQQPPQQPPQQQPPPPPGLLVRQNSCPPA 377 G + +P G + ++G P + P + P P PP PG PP Sbjct: 568 PGTQGLP-GPQGAIG-------PHGEKGPQGKPGLPGMPGSDGPPGHPG-----KEGPPG 614 Query: 378 LPRPQQGEAGTPSGGLQDGGP 398 + QG +G P G L GP Sbjct: 615 -TKGNQGPSG-PQGPLGYPGP 633 Score = 32.0 bits (71), Expect = 4.0 Identities = 44/157 (28%), Positives = 61/157 (38%), Gaps = 17/157 (10%) Query: 1056 EDEVSSSSDNPQALVKASRSPLVTGSPK-----LPPRGVGAGEHGPKAPPPALGL-GIMS 1109 E+E+ SS P L +A+ P K L P + G GP+ P +G GI Sbjct: 273 EEEILESSLLPP-LEEAAHGPRGLKGEKGEPAVLEPGMLVEGPPGPEGPAGLIGPPGIQG 331 Query: 1110 NSTSTPDSYGGGGGPGHPGTPGLEQVRTPTSSS-------GAPPPDEIHPLEILQAQIQL 1162 N D G G PG G PG + P +S G+ D+ + +AQ Q Sbjct: 332 NPGPVGDP-GERGPPGRAGLPGSDGAPGPPGTSLMLPFRFGSGGGDKGPVVAAQEAQAQA 390 Query: 1163 QRQQFSISEDQPLGLKG--GKKGECAVGASGAQNGDS 1197 QQ ++ P G G G+ G S G+S Sbjct: 391 ILQQARLALRGPPGPMGYTGRPGPLGQPGSPGLKGES 427 >gi|111118968 collagen, type XI, alpha 2 isoform 3 preproprotein [Homo sapiens] Length = 1629 Score = 97.1 bits (240), Expect = 1e-19 Identities = 152/603 (25%), Positives = 193/603 (32%), Gaps = 58/603 (9%) Query: 571 RQPNLAQLGHPGDVGQGGLVHGGPVGGLAQPNFEREGGSTGA-GRLGTFEQQAPHLAQES 629 RQ LG PG G G + G + P ER G TG G+ G A+ + Sbjct: 699 RQGPKGSLGFPGFPGASGEKGARGLSGKSGPRGER--GPTGPRGQRGPRGATGKSGAKGT 756 Query: 630 AWFSGPHPPPGDL-LPRRMGGSGLPADCGPHDPSLAPPPPPGGSGVLFRGPLQEPMRMPG 688 + GPH PPG+ LP G +G P GP P PPG G+ + + G Sbjct: 757 SGGDGPHGPPGERGLPGPQGPNGFPGPKGP-------PGPPGKDGLPGHPGQRGEVGFQG 809 Query: 689 EGHVPALPSPGLQFG--GSLGGLGQLQSPGAGVGLPSAASERRPPPPDFATSALGGQPGF 746 + P P G G G +G+ PG P + P G PG Sbjct: 810 KTGPPGPPGVVGPQGAAGETGPMGERGHPG-----PPGPPGEQGLPGTAGKEGTKGDPGP 864 Query: 747 PFGAAGRQSTP--HSGPGVNSPPSAGGGGGSSGGGGGGGAYPPQPDFQPSQRTSASKLGA 804 P GA G+ PG P GG G G G G PP P P +R +A G Sbjct: 865 P-GAPGKDGPAGLRGFPGERGLPGTAGGPGLKGNEGPSG--PPGPAGSPGERGAAGSGGP 921 Query: 805 LSLGSFNKPSSKDNLFGQSCLAALS-----TACQNMIASLGAPNLNVTFNKKNPPEGKRK 859 + P G+ + T + +G P P G Sbjct: 922 IGPPGRPGPQGPPGAAGEKGVPGEKGPIGPTGRDGVQGPVGLPG----------PAGPPG 971 Query: 860 LSQNETDGAAVAGNPGSDYFPGGTAP-GAPGPGGPSGTSSSGSKASGPPNPPAQGDGTSL 918 ++ + D V G+PG G G PGP GP G A P A+G Sbjct: 972 VAGEDGDKGEV-GDPGQKGTKGNKGEHGPPGPPGPIGPVGQPGAAGADGEPGARGPQGHF 1030 Query: 919 SPNYTLESTSGNDGKPVSGG--GGRGRGRRKRDSGHVSP----GTFFDKYSAAPDSGGAP 972 E T G +G P G G G K ++G V P G + A P+ P Sbjct: 1031 GAKGD-EGTRGFNGPPGPIGLQGLPGPSGEKGETGDVGPMGPPGPPGPRGPAGPNGADGP 1089 Query: 973 GVSPGQQQASGAAVGGSSAGETRGAPTPHEKALTSPSWGKGAELLLGDQPDLIG--SLDG 1030 PG G GE+ E + P +G + G QP G G Sbjct: 1090 QGPPGGVGNLGPPGEKGEPGESGSPGIQGEPGVKGPRGERGEKGESG-QPGEPGPPGPKG 1148 Query: 1031 GAKSDSSSPNVGEFASDEVSTSYANEDEVSSSSDNPQALVKASRSPLVTGSPKLPPRGVG 1090 D N G D P+ A G P P Sbjct: 1149 PTGDDGPKGNPGPVGFPG--------DPGPPGEGGPRGQDGAKGDRGEDGEPGQPGSPGP 1200 Query: 1091 AGEHGPKAPPPALGLGIMSNSTSTPDSYGGGGGPGHPGTPGLEQVRTPTSSSGAPPPDEI 1150 GE+GP P G S G G PG G PG P +G P PD + Sbjct: 1201 TGENGPPGPLGKRGPAGSPGSEGRQGGKGAKGDPGAIGAPGKTGPVGPAGPAGKPGPDGL 1260 Query: 1151 HPL 1153 L Sbjct: 1261 RGL 1263 Score = 87.4 bits (215), Expect = 8e-17 Identities = 292/1162 (25%), Positives = 364/1162 (31%), Gaps = 265/1162 (22%) Query: 43 GPPGPVDPAMSALGEPPILGMNMEPYGFHARGHSELHAGGLQAQPVHGFFGGQQPHHGHP 102 GPPG A G GM +P RG L GL + H G Q G P Sbjct: 422 GPPGKAGRRGRA-GADGARGMPGDPGVKGDRGFDGLP--GLPGEKGHRGDTGAQGLPGPP 478 Query: 103 GSHHPHQHHPHFGGNFGGPDPGASCLHGGRLLGYGGAAGGLGSQPPFAEGYEHMAESQGP 162 G G PG S G LLG G G G PP G M QGP Sbjct: 479 GEDGERGDDGEIGPR---GLPGESGPRG--LLGPKGPPGIPG--PPGVRG---MDGPQGP 528 Query: 163 E-SFGPQ-RPGNLPDFHSSGASSHAVPAPCLPL----DQSPNRAASFHGLPSSSGSDSHS 216 + S GPQ PG P + +P P + ++ P G+P S G H Sbjct: 529 KGSLGPQGEPG--PPGQQGTPGTQGLPGPQGAIGPHGEKGPQGKPGLPGMPGSDGPPGH- 585 Query: 217 LEPRRVTNQGAVDSLEYNYPG-EAPSGHFDMFSPSDSEGQLPHYAAGRQVPGGAFPGASA 275 PG E P G PS +G L +PG Sbjct: 586 -------------------PGKEGPPGTKGNQGPSGPQGPL------------GYPGPRG 614 Query: 276 MPRAAGMVGLSKMHAQPPQQQPQQQQQPQQQQQQHGVFFERFSGARKMPVGLEPSVGSRH 335 + G+ GL K H + ++ + G F F G +G++ G R Sbjct: 615 VKGVDGIRGL-KGH--------------KGEKGEDG--FPGFKG----DIGVK---GDRG 650 Query: 336 PLMQPPQQAPPPPQQQPPQQPPQQQPPPPPGLLVRQNSCPPALPRPQQGEAGTPSGGLQD 395 + P + P+ + P P PP + + P LP G G P G L Sbjct: 651 EVGVPGSRGEDGPEGPKGRTGPTGDPGPPGLMGEKGKLGVPGLPG-YPGRQG-PKGSL-- 706 Query: 396 GGPMLPSQHAQFEYPIHRLENRSMHPYSEPVFSMQHPPPQQAPNQRLQHFDAPPYMNVAK 455 G P P A E L +S P ++ P Sbjct: 707 GFPGFPG--ASGEKGARGLSGKS------------GPRGERGPTG--------------- 737 Query: 456 RPRFDFPGSAGVDRCASWNGSMHNGALDNHLSPSAYPGLPGEFTPPVPDSFPS-----GP 510 PR G G +G+ D P GLPG P P+ FP GP Sbjct: 738 -PR----GQRGPRGATGKSGAKGTSGGDGPHGPPGERGLPG---PQGPNGFPGPKGPPGP 789 Query: 511 PLQHPAPDHQSLQQQQQQQQQQQQQQQQQQQQQQQQQQQQRQNAALMIKQMASRNQQQRL 570 P + P H Q+ + Q + Q AA M R Sbjct: 790 PGKDGLPGHPG--------QRGEVGFQGKTGPPGPPGVVGPQGAAGETGPMGERGHPGPP 841 Query: 571 RQPNLAQLGHPGDVGQGGLVHG-GPVGGLAQPN------FEREGGSTG-AGRLGTFEQQA 622 P + G PG G+ G GP G + F E G G AG G + Sbjct: 842 GPPG--EQGLPGTAGKEGTKGDPGPPGAPGKDGPAGLRGFPGERGLPGTAGGPGLKGNEG 899 Query: 623 PHLAQESAWFSGPHPPPGDLLPRRMGGSGLPADCGPHDPSLAPPP--PPGGSGVLF---- 676 P SGP P G R GSG GP P P P PPG +G Sbjct: 900 P---------SGPPGPAGSPGERGAAGSG-----GPIGPPGRPGPQGPPGAAGEKGVPGE 945 Query: 677 RGPL--------QEPMRMPGEGHVPALPSPGLQFGGSLGGLGQLQSPGAGVGLPSAASER 728 +GP+ Q P+ +PG PA P PG+ G G G++ PG G E Sbjct: 946 KGPIGPTGRDGVQGPVGLPG----PAGP-PGV--AGEDGDKGEVGDPGQK-GTKGNKGEH 997 Query: 729 RPPPPDFATSALG--------GQPGFP-----FGAAGRQSTPHSGPGVNSPPSAGGGGGS 775 PP P +G G+PG FGA G + T G N PP G G Sbjct: 998 GPPGPPGPIGPVGQPGAAGADGEPGARGPQGHFGAKGDEGTR----GFNGPPGPIGLQGL 1053 Query: 776 SGGGGG----GGAYPPQPDFQPSQRTSASKLGALS-------LGSFNKPSSKDNLFGQSC 824 G G G P P P R A GA +G+ P K G+S Sbjct: 1054 PGPSGEKGETGDVGPMGPPGPPGPRGPAGPNGADGPQGPPGGVGNLGPPGEKGEP-GESG 1112 Query: 825 LAALS--TACQNMIASLGAPNLNVTFNKKNPPEGKRKLSQNETDGAAVAGNPGSDYFPGG 882 + + G + + PP K T GNPG FPG Sbjct: 1113 SPGIQGEPGVKGPRGERGEKGESGQPGEPGPPGPK-----GPTGDDGPKGNPGPVGFPGD 1167 Query: 883 TAPGAPGPGGPSGTSSS-GSKAS-GPPNPPAQGDGTSLSPNYTLESTSGNDGKPVSGGGG 940 PG PG GGP G + G + G P P T + G G P S G Sbjct: 1168 --PGPPGEGGPRGQDGAKGDRGEDGEPGQPGSPGPTGENGPPGPLGKRGPAGSPGSEGRQ 1225 Query: 941 RGRGRRKRDSGHVSPGTFFDKYSAAPDSG-------GAPGVSPGQQQASGAAVGGSSAGE 993 G+G + +PG A P G PG S GQQ GA AG Sbjct: 1226 GGKGAKGDPGAIGAPGKTGPVGPAGPAGKPGPDGLRGLPG-SVGQQGRPGAT---GQAGP 1281 Query: 994 TRGAPTPHEKALTSPSWGKGAELLLGDQPDLIGSL----DGGAKSDSSSPNVGEFASDEV 1049 P L + KG + P LIG + + G K D P Sbjct: 1282 PGPVGPPGLPGLRGDAGAKGEK----GHPGLIGLIGPPGEQGEKGDRGLPG--------- 1328 Query: 1050 STSYANEDEVSSSSDNPQALVKASRSPLVTGSPKLPPRGVGAGEHGPKAPPPALGLGIMS 1109 S + + + P+ G P P G GPK A G G Sbjct: 1329 --------PQGSPGQKGEMGIPGASGPIGPGGPPGLP-----GPAGPKGAKGATGPG--- 1372 Query: 1110 NSTSTPDSYGGGGGPGHPGTPG 1131 G G PGHPG PG Sbjct: 1373 ---GPKGEKGVQGPPGHPGPPG 1391 Score = 85.5 bits (210), Expect = 3e-16 Identities = 159/615 (25%), Positives = 192/615 (31%), Gaps = 116/615 (18%) Query: 579 GHPGDVG-QGGLVHGGPVGGLAQPNFEREGGSTG----AGRLGTFEQQAPHLAQESAWFS 633 G PG VG QG GP+G P G G AG+ GT P A + Sbjct: 815 GPPGVVGPQGAAGETGPMGERGHPGPPGPPGEQGLPGTAGKEGTKGDPGPPGAPGKDGPA 874 Query: 634 GPHPPPGDL-LPRRMGGSGLPADCGPHDPSLAPPPPPGGSGVLFRG-PLQEPMRMPGEGH 691 G PG+ LP GG GL + GP P P PG G G P+ P R +G Sbjct: 875 GLRGFPGERGLPGTAGGPGLKGNEGPSGPP-GPAGSPGERGAAGSGGPIGPPGRPGPQGP 933 Query: 692 VPALPSPGLQFGGSLGGLGQLQSPGAG--VGLPSAASERRPPPPDFATSALGGQPGFPFG 749 A G+ G G +G G VGLP A PP G+ G P G Sbjct: 934 PGAAGEKGVP--GEKGPIGPTGRDGVQGPVGLPGPAG----PPGVAGEDGDKGEVGDP-G 986 Query: 750 AAGRQSTP--HSGPGVNSPPSAGGGGGSSGGGGGGGAYPPQPDF----QPSQRTSASKLG 803 G + H PG P G G++G G GA PQ F R G Sbjct: 987 QKGTKGNKGEHGPPGPPGPIGPVGQPGAAGADGEPGARGPQGHFGAKGDEGTRGFNGPPG 1046 Query: 804 ALSLGSFNKPSSKDNLFGQSCLAALSTACQNMIASLGAPNLNVTFNKKNPPEGKRKLSQN 863 + L PS + G + +G P PP + N Sbjct: 1047 PIGLQGLPGPSGEKGETGD-------------VGPMGPPG---------PPGPRGPAGPN 1084 Query: 864 ETDGA-------------AVAGNPGSDYFPGGTA-PGAPGPGGPSGTSSSGSKAS--GPP 907 DG G PG PG PG GP G G + GPP Sbjct: 1085 GADGPQGPPGGVGNLGPPGEKGEPGESGSPGIQGEPGVKGPRGERGEKGESGQPGEPGPP 1144 Query: 908 NP--PAQGDGTSLSPNYTLESTSGNDGKPVSGGGGRGRGRRKRDSGHV-------SPGTF 958 P P DG +P G+ G P GG RG+ K D G SPG Sbjct: 1145 GPKGPTGDDGPKGNPGPV--GFPGDPGPP-GEGGPRGQDGAKGDRGEDGEPGQPGSPGPT 1201 Query: 959 FDKYSAAPDSGGAPGVSPGQQQASGAAVGGSSAGETRGAPTPHEKALTSPSWGKGAELLL 1018 + P P SPG + G G + G+ P + P+ G Sbjct: 1202 GENGPPGPLGKRGPAGSPGSEGRQG---GKGAKGDPGAIGAPGKTGPVGPAGPAGKP--- 1255 Query: 1019 GDQPDLIGSLDGGAKSDSSSPNVGEFASDEVSTSYANEDEVSSSSDNPQALVKASRSPLV 1078 PD + L G +VG+ P A +A P Sbjct: 1256 --GPDGLRGLPG---------SVGQ-------------------QGRPGATGQAG-PPGP 1284 Query: 1079 TGSPKLPPRGVGAGEHGPKAPPPALGL------GIMSNSTSTPDSYGGGGGPGHPGTPGL 1132 G P LP AG G K P +GL P G G G G PG Sbjct: 1285 VGPPGLPGLRGDAGAKGEKGHPGLIGLIGPPGEQGEKGDRGLPGPQGSPGQKGEMGIPGA 1344 Query: 1133 EQVRTPTSSSGAPPP 1147 P G P P Sbjct: 1345 SGPIGPGGPPGLPGP 1359 Score = 79.7 bits (195), Expect = 2e-14 Identities = 246/1018 (24%), Positives = 319/1018 (31%), Gaps = 205/1018 (20%) Query: 82 GLQAQP-VHGFFGGQQPHHGHPGSHHPHQHHPHFGGNFGGPDPGASCLHGGRLLGYGGAA 140 G+ P V G G Q P GS P Q P G G PG L G + GA Sbjct: 512 GIPGPPGVRGMDGPQGPK----GSLGP-QGEPGPPGQQG--TPGTQGLPGPQ-----GAI 559 Query: 141 GGLGSQPPFAE-GYEHMAESQGPESFGPQRPGNLPDFHSSGASSHAVPAPCL--PLDQSP 197 G G + P + G M S GP P PG + G + P L P + Sbjct: 560 GPHGEKGPQGKPGLPGMPGSDGP----PGHPGKEGPPGTKGNQGPSGPQGPLGYPGPRGV 615 Query: 198 NRAASFHGLPSSSGSDSHSLEPRRVTNQGAV-DSLEYNYPG----EAPSGHFDMFSPSDS 252 GL G P + G D E PG + P G P+ Sbjct: 616 KGVDGIRGLKGHKGEKGEDGFPGFKGDIGVKGDRGEVGVPGSRGEDGPEGPKGRTGPTGD 675 Query: 253 EGQ--------------LPHYAAGRQVPGGA-----FPGASAMPRAAGMVGLSKMHAQPP 293 G LP Y GRQ P G+ FPGAS A G+ G S + Sbjct: 676 PGPPGLMGEKGKLGVPGLPGYP-GRQGPKGSLGFPGFPGASGEKGARGLSGKSGPRGERG 734 Query: 294 QQQPQQQQQPQQQQQQHGVFFERFSGARKMPVGLEPSVGSRHPLMQPPQQAPPPPQQQP- 352 P+ Q+ P+ + G P G G + P P + PP P + Sbjct: 735 PTGPRGQRGPRGATGKSGAKGTSGGDGPHGPPGERGLPGPQGPNGFPGPKGPPGPPGKDG 794 Query: 353 -PQQPPQQQ---------PPPPPGLLVRQNSCPPALPRPQQGEAGTPSGGLQDGGPMLPS 402 P P Q+ PP PPG++ Q + P ++G G P + G P Sbjct: 795 LPGHPGQRGEVGFQGKTGPPGPPGVVGPQGAAGETGPMGERGHPGPPGPPGEQGLPGTAG 854 Query: 403 QHAQFEYPIHRLENRSMHPYSEPVFSMQHPPPQQAPNQRLQHFDAPPYMNVAKRPRFDFP 462 + + P P AP + D P + FP Sbjct: 855 KEG----------------------TKGDPGPPGAPGK-----DGPAGLR-------GFP 880 Query: 463 GSAGVDRCASWNGSMHNGALDNHLSPSAYPGLPGEFTPPVPDSFPSGPPLQHPA-PDHQS 521 G G+ A G L + PS PG G +P + SG P+ P P Q Sbjct: 881 GERGLPGTAGGPG------LKGNEGPSGPPGPAG--SPGERGAAGSGGPIGPPGRPGPQG 932 Query: 522 LQQQQQQQQQQQQQQQQQQQQQQQQQQQQRQNAALMIKQMASRNQQQRLRQPNLAQLGHP 581 ++ ++ + Q +A + + ++G P Sbjct: 933 PPGAAGEKGVPGEKGPIGPTGRDGVQGPVGLPGPAGPPGVAGEDGDK-------GEVGDP 985 Query: 582 GDVGQGGLV--HG-----GPVGGLAQPNFEREGGSTGA-GRLGTFEQQAPHLAQESAWFS 633 G G G HG GP+G + QP G GA G G F + + + F+ Sbjct: 986 GQKGTKGNKGEHGPPGPPGPIGPVGQPGAAGADGEPGARGPQGHFGAKGD---EGTRGFN 1042 Query: 634 GPHPPPG-DLLPRRMGGSGLPADCGPHDPSLAPPP--------------PPGGSGVLFRG 678 GP P G LP G G D GP P P P PPGG G L G Sbjct: 1043 GPPGPIGLQGLPGPSGEKGETGDVGPMGPPGPPGPRGPAGPNGADGPQGPPGGVGNL--G 1100 Query: 679 PLQEPMRMPGEGHVPALPS-PGLQFG----GSLGGLGQLQSPGAG--------------- 718 P E PGE P + PG++ G G GQ PG Sbjct: 1101 PPGEKGE-PGESGSPGIQGEPGVKGPRGERGEKGESGQPGEPGPPGPKGPTGDDGPKGNP 1159 Query: 719 -----VGLPSAASERRPPPPDFATSALG-----GQPGFP-----------FGAAGRQSTP 757 G P E P D A G GQPG P G G +P Sbjct: 1160 GPVGFPGDPGPPGEGGPRGQDGAKGDRGEDGEPGQPGSPGPTGENGPPGPLGKRGPAGSP 1219 Query: 758 HS-----GPGVNSPPSAGGGGGSSGG-GGGGGAYPPQPDFQ---PSQRTSASKLGALSLG 808 S G G P A G G +G G G A P PD P + GA Sbjct: 1220 GSEGRQGGKGAKGDPGAIGAPGKTGPVGPAGPAGKPGPDGLRGLPGSVGQQGRPGATGQA 1279 Query: 809 SFNKPSSKDNLFGQSCLAALS--TACQNMIASLGAPNLNVTFNKKNPPEGKRKLSQNETD 866 P L G A +I +G P + P + Q Sbjct: 1280 GPPGPVGPPGLPGLRGDAGAKGEKGHPGLIGLIGPPGEQGEKGDRGLPGPQGSPGQKGEM 1339 Query: 867 GAAVAGNPGSDYFPGGTAPGAPGPGGPSGTSSSGSKASGPPNPPAQGDGTSLSPNYTLES 926 G A P PGG PG PGP GP G A+GP P + ++ Sbjct: 1340 GIPGASGPIG---PGGP-PGLPGPAGPKGAKG----ATGPGGPKGEKG---------VQG 1382 Query: 927 TSGNDGKPVSGGGGRGRGRRKRDSGHVSPGTFFDKYSAAPDSGGAPGVSPGQQQASGA 984 G+ G P K+ V + A P +GGAPG G ++ G+ Sbjct: 1383 PPGHPGPPGEVIQPLPIQMPKKTRRSVDGSRLMQEDEAIP-TGGAPGSPGGLEEIFGS 1439 Score = 76.3 bits (186), Expect = 2e-13 Identities = 173/718 (24%), Positives = 225/718 (31%), Gaps = 143/718 (19%) Query: 524 QQQQQQQQQQQQQQQQQQQQQQQQQQQRQNAALMIKQMASRNQQQRLRQPNLAQLGHPGD 583 Q QQ + Q+ QQQ + + Q Q+ + AA + + + + +P + G PG Sbjct: 237 QNQQPHRAQRSPQQQPSRLHRPQNQEPQSQAAHGPRGLKGEKGEPAVLEPGMLVEGPPGP 296 Query: 584 VGQGGLVHGGPVGGLAQPNFEREGGSTG-AGRLGTFEQQAPHLAQESAWFSGPHPPPGD- 641 G GL+ GP G P + G G GR G G PPG Sbjct: 297 EGPAGLI--GPPGIQGNPGPVGDPGERGPPGRAGL------------PGSDGAPGPPGTS 342 Query: 642 -LLPRRMGGSGLPADCGP-------------HDPSLAPPPPPGGSGVLFR-GPLQEPMRM 686 +LP R G G D GP LA PPG G R GPL +P Sbjct: 343 LMLPFRFGSGG--GDKGPVVAAQEAQAQAILQQARLALRGPPGPMGYTGRPGPLGQP--- 397 Query: 687 PGEGHVPALPSPGLQ-FGGSLGGLGQLQSPGAGVGLPSAASERRPPPPDFATSALGGQPG 745 SPGL+ G LG G + P G P A R D A G PG Sbjct: 398 ---------GSPGLKGESGDLGPQGP-RGPQGLTGPPGKAGRRGRAGADGAR----GMPG 443 Query: 746 FPFGAAGRQSTPHSGPGVNSPPSAGGGGGSSGGGGGGGAYPPQPDFQPSQRTSASKLGAL 805 P G G + G + P G G G G G P P + +R ++G Sbjct: 444 DP-GVKGDR-------GFDGLPGLPGEKGHRGDTGAQGL--PGPPGEDGERGDDGEIGPR 493 Query: 806 SLGSFNKPSSKDNLFGQSCLAALSTACQNMIASLGAPNLNVTFNKKNPPEGKRKLS-QNE 864 L + P L G G P P K L Q E Sbjct: 494 GLPGESGPR---GLLGPK-------------GPPGIPGPPGVRGMDGPQGPKGSLGPQGE 537 Query: 865 TDGAAVAGNPGSDYFPGGTAPGAPGPGGPSGTSSSGS-----KASGPPNPPAQGDGTSLS 919 G PG+ PG GA GP G G + GPP P + Sbjct: 538 PGPPGQQGTPGTQGLPG--PQGAIGPHGEKGPQGKPGLPGMPGSDGPPGHPGKEGPPGTK 595 Query: 920 PNYTLESTSGNDGKPVSGG-----GGRGRGRRKRDSGHVSPGTFFDKYSAAPDSG--GAP 972 N G G P G G RG K + G F D G G P Sbjct: 596 GNQGPSGPQGPLGYPGPRGVKGVDGIRGLKGHKGEKGEDGFPGFKGDIGVKGDRGEVGVP 655 Query: 973 GVSPGQQQASGAAVGGSSAGETRGAPTPHEKALTSPSWGKGAELLLGDQPDL-IGSLDG- 1030 G S G+ G K T P+ G L+G++ L + L G Sbjct: 656 G-SRGEDGPEG------------------PKGRTGPTGDPGPPGLMGEKGKLGVPGLPGY 696 Query: 1031 ----GAKSDSSSPNVGEFASDEVSTSYANEDEVSSSSDNPQALVKASRSPL-VTGSPKLP 1085 G K P + ++ + + + + + R P TG Sbjct: 697 PGRQGPKGSLGFPGFPGASGEKGARGLSGKS--GPRGERGPTGPRGQRGPRGATGKSGAK 754 Query: 1086 PRGVGAGEHGP---KAPPPALGLGIMSNSTSTPDSYGGGGGPGHPGTPGLEQVRTPTSSS 1142 G G HGP + P G P G G PGHPG G + T Sbjct: 755 GTSGGDGPHGPPGERGLPGPQGPNGFPGPKGPPGPPGKDGLPGHPGQRGEVGFQGKTGPP 814 Query: 1143 GAPPPDEIHPLEILQAQIQLQRQQFSISEDQPLGLKG-----GKKGECAVGASGAQNG 1195 G PP + P Q + E P+G +G G GE + + + G Sbjct: 815 G--PPGVVGP-------------QGAAGETGPMGERGHPGPPGPPGEQGLPGTAGKEG 857 Score = 74.3 bits (181), Expect = 7e-13 Identities = 241/1005 (23%), Positives = 313/1005 (31%), Gaps = 193/1005 (19%) Query: 293 PQQQPQQQQQPQQQQQQ----HGVFFERFSGARKMPVGLEPSV---GSRHPLMQPPQQAP 345 PQQQP + +PQ Q+ Q HG G + P LEP + G P P Sbjct: 248 PQQQPSRLHRPQNQEPQSQAAHGP--RGLKGEKGEPAVLEPGMLVEGPPGPEGPAGLIGP 305 Query: 346 PPPQQQP-PQQPPQQQPPPPPGLLVRQNSCPPALPRPQQGEAGTP--------SGGLQDG 396 P Q P P P ++ PP L + P G GT SGG D Sbjct: 306 PGIQGNPGPVGDPGERGPPGRAGLPGSDGAP--------GPPGTSLMLPFRFGSGG-GDK 356 Query: 397 GPMLPSQHAQFEYPIHRLENRSMHPYSEPVFSMQHPPPQQAPNQRL-------------- 442 GP++ +Q AQ + + + P ++ + P Q + L Sbjct: 357 GPVVAAQEAQAQAILQQARLALRGPPGPMGYTGRPGPLGQPGSPGLKGESGDLGPQGPRG 416 Query: 443 -QHFDAPPYMNVAKRPRF------DFPGSAGVDRCASWNGSMHNGALDNHLSPSAYPGLP 495 Q PP +R R PG GV ++G H + GLP Sbjct: 417 PQGLTGPP-GKAGRRGRAGADGARGMPGDPGVKGDRGFDGLPGLPGEKGHRGDTGAQGLP 475 Query: 496 GEFTPPVPDS-----------------------FPSGPPLQHPAPDHQSLQ-QQQQQQQQ 531 G PP D P GPP P + + Q + Sbjct: 476 G---PPGEDGERGDDGEIGPRGLPGESGPRGLLGPKGPPGIPGPPGVRGMDGPQGPKGSL 532 Query: 532 QQQQQQQQQQQQQQQQQQQRQNAALMIKQMASRNQQQRLRQPNL----AQLGHPGDVG-- 585 Q + QQ Q I + Q + P + GHPG G Sbjct: 533 GPQGEPGPPGQQGTPGTQGLPGPQGAIGPHGEKGPQGKPGLPGMPGSDGPPGHPGKEGPP 592 Query: 586 -----------QGGLVHGGPVG--------GL----------AQPNFEREGGSTG----A 612 QG L + GP G GL P F+ + G G Sbjct: 593 GTKGNQGPSGPQGPLGYPGPRGVKGVDGIRGLKGHKGEKGEDGFPGFKGDIGVKGDRGEV 652 Query: 613 GRLGTFEQQAPHLAQESAWFSGPHPPPGDLLPR-RMGGSGLPADCGPHDP--SLAPPPPP 669 G G+ + P + +G PPG + + ++G GLP G P SL P P Sbjct: 653 GVPGSRGEDGPEGPKGRTGPTGDPGPPGLMGEKGKLGVPGLPGYPGRQGPKGSLGFPGFP 712 Query: 670 GGSGVLFRGPLQEPMRMPGE----------GHVPALPSPGLQFGGSLGGLGQLQSPGAGV 719 G SG L GE G A G + G+ GG G PG Sbjct: 713 GASGEKGARGLSGKSGPRGERGPTGPRGQRGPRGATGKSGAK--GTSGGDGPHGPPGER- 769 Query: 720 GLPSAASERRPPPPDFATSALG--GQPGFP--FGAAGRQ--STPHSGPGVNSPPSAGGGG 773 GLP P P G G PG P G G Q + P PGV P A G Sbjct: 770 GLPGPQGPNGFPGPKGPPGPPGKDGLPGHPGQRGEVGFQGKTGPPGPPGVVGPQGAAGET 829 Query: 774 GSSGGGGGGGAYPPQPDFQPSQRTSASKLGALSLGSFNKPSSKDNLFGQSCLAALS--TA 831 G G G G PP P + +A K G + G P + G+ A L Sbjct: 830 GPMGERGHPG--PPGPPGEQGLPGTAGKEG--TKGDPGPPGAP----GKDGPAGLRGFPG 881 Query: 832 CQNMIASLGAPNLNVTFNKKNPPEGKRKLSQNETDGA----AVAGNPGSDYFPGGT---- 883 + + + G P L PP + G+ G PG PG Sbjct: 882 ERGLPGTAGGPGLKGNEGPSGPPGPAGSPGERGAAGSGGPIGPPGRPGPQGPPGAAGEKG 941 Query: 884 APGAPGPGGPSGTSSSGSKAS--GPPNPPA----QGD-GTSLSPNYTLESTSGNDGK--- 933 PG GP GP+G GP PP GD G P + T GN G+ Sbjct: 942 VPGEKGPIGPTGRDGVQGPVGLPGPAGPPGVAGEDGDKGEVGDPGQ--KGTKGNKGEHGP 999 Query: 934 -----PVSGGGGRGRGRRKRDSGHVSP-GTFFDKYSAAPDSGGAPGVSPGQQQASGAAVG 987 P+ G G + G P G F K P G Q G + Sbjct: 1000 PGPPGPIGPVGQPGAAGADGEPGARGPQGHFGAKGDEGTRGFNGPPGPIGLQGLPGPSGE 1059 Query: 988 GSSAGETRGAPTPHEKALTSPSWGKGAELLLGDQPDLIGSL----DGGAKSDSSSPNVGE 1043 G+ P P+ GA+ G P +G+L + G +S SP + Sbjct: 1060 KGETGDVGPMGPPGPPGPRGPAGPNGADGPQG-PPGGVGNLGPPGEKGEPGESGSPGIQ- 1117 Query: 1044 FASDEVSTSYANEDEVSSSSDNPQALVKASRSPLVTGSPKLPPRGVG-AGEHGPKAPPPA 1102 V E S + + P PK P VG G+ GP Sbjct: 1118 -GEPGVKGPRGERGEKGESGQPGEPGPPGPKGPTGDDGPKGNPGPVGFPGDPGPP----- 1171 Query: 1103 LGLGIMSNSTSTPDSYGGGGGPGHPGTPGLEQVRTPTSSSGAPPP 1147 G G G G PG PG+PG PT +G P P Sbjct: 1172 -GEGGPRGQDGAKGDRGEDGEPGQPGSPG------PTGENGPPGP 1209 Score = 40.4 bits (93), Expect = 0.011 Identities = 97/381 (25%), Positives = 122/381 (32%), Gaps = 73/381 (19%) Query: 37 PAFHTGGPPGPVDPAMSALGEPPILGMNMEPYGFHARGHSELHAGGLQAQPVHGFFGGQQ 96 P GPPGP PA +G P I G N P G G + P G Sbjct: 286 PGMLVEGPPGPEGPA-GLIGPPGIQG-NPGPVG----------DPGERGPPGRAGLPGSD 333 Query: 97 PHHGHPGSHHPHQHHPHFGGNFGGPDPGA------SCLHGGRL--------LGYGGAAGG 142 G PG+ GG GP A + L RL +GY G G Sbjct: 334 GAPGPPGTSLMLPFRFGSGGGDKGPVVAAQEAQAQAILQQARLALRGPPGPMGYTGRPGP 393 Query: 143 LGSQP--PFAEGYEHMAESQGPESFGPQRPGNLPDFHSSGASSHAVPAPCLPLDQSPNRA 200 LG QP P +G QGP GPQ P + A A +P D Sbjct: 394 LG-QPGSPGLKGESGDLGPQGPR--GPQGLTGPPGKAGRRGRAGADGARGMPGDPGVKGD 450 Query: 201 ASFHGLPSSSGSDSHSLEPRRVTNQGAVDSLEYNYPGEAPSGHFDMFSPSDSEGQL-PHY 259 F GLP G H D+ PG P G +G++ P Sbjct: 451 RGFDGLPGLPGEKGH-----------RGDTGAQGLPG--PPGE---DGERGDDGEIGPRG 494 Query: 260 AAGRQVPGGAF--PGASAMPRAAGMVGLSKMHAQPPQQQPQQQQQPQQQQQQHGVFFERF 317 G P G G +P G+ G+ PQ + P QQ Sbjct: 495 LPGESGPRGLLGPKGPPGIPGPPGVRGMDGPQGPKGSLGPQGEPGPPGQQGT-------- 546 Query: 318 SGARKMPVGLEPSVGSRHPLMQPPQQAPPPPQQQPPQQPPQQQPPPPPGLLVRQNSCPPA 377 G + +P G + ++G P + P + P P PP PG PP Sbjct: 547 PGTQGLP-GPQGAIG-------PHGEKGPQGKPGLPGMPGSDGPPGHPG-----KEGPPG 593 Query: 378 LPRPQQGEAGTPSGGLQDGGP 398 + QG +G P G L GP Sbjct: 594 -TKGNQGPSG-PQGPLGYPGP 612 Score = 33.9 bits (76), Expect = 1.1 Identities = 86/346 (24%), Positives = 110/346 (31%), Gaps = 44/346 (12%) Query: 95 QQPHHGH-PGSHHPHQHHPHFGGNFGGPDPGASCLHGGRLL----GYGGAAGGLGSQPPF 149 QQP H P + P H G + L G L+ G G AG +G PP Sbjct: 250 QQPSRLHRPQNQEPQSQAAHGPRGLKGEKGEPAVLEPGMLVEGPPGPEGPAGLIG--PPG 307 Query: 150 AEGYEHMAESQGPESFGPQRPGNLPDFHSSGASSHAVPAPCLPLDQSPNRAASFHGLPSS 209 +G G GP LP S GA + LP + + Sbjct: 308 IQGNPGPVGDPGER--GPPGRAGLPG--SDGAPGPPGTSLMLPFRFGSGGGDKGPVVAAQ 363 Query: 210 SGSDSHSLEPRRVTNQGAVDSLEYN-------YPG----EAPSGHFDMFSPSDSEGQL-P 257 L+ R+ +G + Y PG + SG P +G P Sbjct: 364 EAQAQAILQQARLALRGPPGPMGYTGRPGPLGQPGSPGLKGESGDLGPQGPRGPQGLTGP 423 Query: 258 HYAAGRQVPGGAFPGASAMPRAAGMVG---LSKMHAQPPQQQPQQQQQPQQQQQQHGVFF 314 AGR+ GA GA MP G+ G + P ++ + Q G Sbjct: 424 PGKAGRRGRAGA-DGARGMPGDPGVKGDRGFDGLPGLPGEKGHRGDTGAQGLPGPPGEDG 482 Query: 315 ERFSGARKMPVGLEPSVGSRHPL--MQPPQQAPPP-------PQ--------QQPPQQPP 357 ER P GL G R L PP PP PQ Q P P Sbjct: 483 ERGDDGEIGPRGLPGESGPRGLLGPKGPPGIPGPPGVRGMDGPQGPKGSLGPQGEPGPPG 542 Query: 358 QQQPPPPPGLLVRQNSCPPALPRPQQGEAGTPSGGLQDGGPMLPSQ 403 QQ P GL Q + P + QG+ G P DG P P + Sbjct: 543 QQGTPGTQGLPGPQGAIGPHGEKGPQGKPGLPGMPGSDGPPGHPGK 588 >gi|111118970 collagen, type XI, alpha 2 isoform 1 preproprotein [Homo sapiens] Length = 1736 Score = 97.1 bits (240), Expect = 1e-19 Identities = 152/603 (25%), Positives = 193/603 (32%), Gaps = 58/603 (9%) Query: 571 RQPNLAQLGHPGDVGQGGLVHGGPVGGLAQPNFEREGGSTGA-GRLGTFEQQAPHLAQES 629 RQ LG PG G G + G + P ER G TG G+ G A+ + Sbjct: 806 RQGPKGSLGFPGFPGASGEKGARGLSGKSGPRGER--GPTGPRGQRGPRGATGKSGAKGT 863 Query: 630 AWFSGPHPPPGDL-LPRRMGGSGLPADCGPHDPSLAPPPPPGGSGVLFRGPLQEPMRMPG 688 + GPH PPG+ LP G +G P GP P PPG G+ + + G Sbjct: 864 SGGDGPHGPPGERGLPGPQGPNGFPGPKGP-------PGPPGKDGLPGHPGQRGEVGFQG 916 Query: 689 EGHVPALPSPGLQFG--GSLGGLGQLQSPGAGVGLPSAASERRPPPPDFATSALGGQPGF 746 + P P G G G +G+ PG P + P G PG Sbjct: 917 KTGPPGPPGVVGPQGAAGETGPMGERGHPG-----PPGPPGEQGLPGTAGKEGTKGDPGP 971 Query: 747 PFGAAGRQSTP--HSGPGVNSPPSAGGGGGSSGGGGGGGAYPPQPDFQPSQRTSASKLGA 804 P GA G+ PG P GG G G G G PP P P +R +A G Sbjct: 972 P-GAPGKDGPAGLRGFPGERGLPGTAGGPGLKGNEGPSG--PPGPAGSPGERGAAGSGGP 1028 Query: 805 LSLGSFNKPSSKDNLFGQSCLAALS-----TACQNMIASLGAPNLNVTFNKKNPPEGKRK 859 + P G+ + T + +G P P G Sbjct: 1029 IGPPGRPGPQGPPGAAGEKGVPGEKGPIGPTGRDGVQGPVGLPG----------PAGPPG 1078 Query: 860 LSQNETDGAAVAGNPGSDYFPGGTAP-GAPGPGGPSGTSSSGSKASGPPNPPAQGDGTSL 918 ++ + D V G+PG G G PGP GP G A P A+G Sbjct: 1079 VAGEDGDKGEV-GDPGQKGTKGNKGEHGPPGPPGPIGPVGQPGAAGADGEPGARGPQGHF 1137 Query: 919 SPNYTLESTSGNDGKPVSGG--GGRGRGRRKRDSGHVSP----GTFFDKYSAAPDSGGAP 972 E T G +G P G G G K ++G V P G + A P+ P Sbjct: 1138 GAKGD-EGTRGFNGPPGPIGLQGLPGPSGEKGETGDVGPMGPPGPPGPRGPAGPNGADGP 1196 Query: 973 GVSPGQQQASGAAVGGSSAGETRGAPTPHEKALTSPSWGKGAELLLGDQPDLIG--SLDG 1030 PG G GE+ E + P +G + G QP G G Sbjct: 1197 QGPPGGVGNLGPPGEKGEPGESGSPGIQGEPGVKGPRGERGEKGESG-QPGEPGPPGPKG 1255 Query: 1031 GAKSDSSSPNVGEFASDEVSTSYANEDEVSSSSDNPQALVKASRSPLVTGSPKLPPRGVG 1090 D N G D P+ A G P P Sbjct: 1256 PTGDDGPKGNPGPVGFPG--------DPGPPGEGGPRGQDGAKGDRGEDGEPGQPGSPGP 1307 Query: 1091 AGEHGPKAPPPALGLGIMSNSTSTPDSYGGGGGPGHPGTPGLEQVRTPTSSSGAPPPDEI 1150 GE+GP P G S G G PG G PG P +G P PD + Sbjct: 1308 TGENGPPGPLGKRGPAGSPGSEGRQGGKGAKGDPGAIGAPGKTGPVGPAGPAGKPGPDGL 1367 Query: 1151 HPL 1153 L Sbjct: 1368 RGL 1370 Score = 87.4 bits (215), Expect = 8e-17 Identities = 292/1162 (25%), Positives = 364/1162 (31%), Gaps = 265/1162 (22%) Query: 43 GPPGPVDPAMSALGEPPILGMNMEPYGFHARGHSELHAGGLQAQPVHGFFGGQQPHHGHP 102 GPPG A G GM +P RG L GL + H G Q G P Sbjct: 529 GPPGKAGRRGRA-GADGARGMPGDPGVKGDRGFDGLP--GLPGEKGHRGDTGAQGLPGPP 585 Query: 103 GSHHPHQHHPHFGGNFGGPDPGASCLHGGRLLGYGGAAGGLGSQPPFAEGYEHMAESQGP 162 G G PG S G LLG G G G PP G M QGP Sbjct: 586 GEDGERGDDGEIGPR---GLPGESGPRG--LLGPKGPPGIPG--PPGVRG---MDGPQGP 635 Query: 163 E-SFGPQ-RPGNLPDFHSSGASSHAVPAPCLPL----DQSPNRAASFHGLPSSSGSDSHS 216 + S GPQ PG P + +P P + ++ P G+P S G H Sbjct: 636 KGSLGPQGEPG--PPGQQGTPGTQGLPGPQGAIGPHGEKGPQGKPGLPGMPGSDGPPGH- 692 Query: 217 LEPRRVTNQGAVDSLEYNYPG-EAPSGHFDMFSPSDSEGQLPHYAAGRQVPGGAFPGASA 275 PG E P G PS +G L +PG Sbjct: 693 -------------------PGKEGPPGTKGNQGPSGPQGPL------------GYPGPRG 721 Query: 276 MPRAAGMVGLSKMHAQPPQQQPQQQQQPQQQQQQHGVFFERFSGARKMPVGLEPSVGSRH 335 + G+ GL K H + ++ + G F F G +G++ G R Sbjct: 722 VKGVDGIRGL-KGH--------------KGEKGEDG--FPGFKG----DIGVK---GDRG 757 Query: 336 PLMQPPQQAPPPPQQQPPQQPPQQQPPPPPGLLVRQNSCPPALPRPQQGEAGTPSGGLQD 395 + P + P+ + P P PP + + P LP G G P G L Sbjct: 758 EVGVPGSRGEDGPEGPKGRTGPTGDPGPPGLMGEKGKLGVPGLPG-YPGRQG-PKGSL-- 813 Query: 396 GGPMLPSQHAQFEYPIHRLENRSMHPYSEPVFSMQHPPPQQAPNQRLQHFDAPPYMNVAK 455 G P P A E L +S P ++ P Sbjct: 814 GFPGFPG--ASGEKGARGLSGKS------------GPRGERGPTG--------------- 844 Query: 456 RPRFDFPGSAGVDRCASWNGSMHNGALDNHLSPSAYPGLPGEFTPPVPDSFPS-----GP 510 PR G G +G+ D P GLPG P P+ FP GP Sbjct: 845 -PR----GQRGPRGATGKSGAKGTSGGDGPHGPPGERGLPG---PQGPNGFPGPKGPPGP 896 Query: 511 PLQHPAPDHQSLQQQQQQQQQQQQQQQQQQQQQQQQQQQQRQNAALMIKQMASRNQQQRL 570 P + P H Q+ + Q + Q AA M R Sbjct: 897 PGKDGLPGHPG--------QRGEVGFQGKTGPPGPPGVVGPQGAAGETGPMGERGHPGPP 948 Query: 571 RQPNLAQLGHPGDVGQGGLVHG-GPVGGLAQPN------FEREGGSTG-AGRLGTFEQQA 622 P + G PG G+ G GP G + F E G G AG G + Sbjct: 949 GPPG--EQGLPGTAGKEGTKGDPGPPGAPGKDGPAGLRGFPGERGLPGTAGGPGLKGNEG 1006 Query: 623 PHLAQESAWFSGPHPPPGDLLPRRMGGSGLPADCGPHDPSLAPPP--PPGGSGVLF---- 676 P SGP P G R GSG GP P P P PPG +G Sbjct: 1007 P---------SGPPGPAGSPGERGAAGSG-----GPIGPPGRPGPQGPPGAAGEKGVPGE 1052 Query: 677 RGPL--------QEPMRMPGEGHVPALPSPGLQFGGSLGGLGQLQSPGAGVGLPSAASER 728 +GP+ Q P+ +PG PA P PG+ G G G++ PG G E Sbjct: 1053 KGPIGPTGRDGVQGPVGLPG----PAGP-PGV--AGEDGDKGEVGDPGQK-GTKGNKGEH 1104 Query: 729 RPPPPDFATSALG--------GQPGFP-----FGAAGRQSTPHSGPGVNSPPSAGGGGGS 775 PP P +G G+PG FGA G + T G N PP G G Sbjct: 1105 GPPGPPGPIGPVGQPGAAGADGEPGARGPQGHFGAKGDEGTR----GFNGPPGPIGLQGL 1160 Query: 776 SGGGGG----GGAYPPQPDFQPSQRTSASKLGALS-------LGSFNKPSSKDNLFGQSC 824 G G G P P P R A GA +G+ P K G+S Sbjct: 1161 PGPSGEKGETGDVGPMGPPGPPGPRGPAGPNGADGPQGPPGGVGNLGPPGEKGEP-GESG 1219 Query: 825 LAALS--TACQNMIASLGAPNLNVTFNKKNPPEGKRKLSQNETDGAAVAGNPGSDYFPGG 882 + + G + + PP K T GNPG FPG Sbjct: 1220 SPGIQGEPGVKGPRGERGEKGESGQPGEPGPPGPK-----GPTGDDGPKGNPGPVGFPGD 1274 Query: 883 TAPGAPGPGGPSGTSSS-GSKAS-GPPNPPAQGDGTSLSPNYTLESTSGNDGKPVSGGGG 940 PG PG GGP G + G + G P P T + G G P S G Sbjct: 1275 --PGPPGEGGPRGQDGAKGDRGEDGEPGQPGSPGPTGENGPPGPLGKRGPAGSPGSEGRQ 1332 Query: 941 RGRGRRKRDSGHVSPGTFFDKYSAAPDSG-------GAPGVSPGQQQASGAAVGGSSAGE 993 G+G + +PG A P G PG S GQQ GA AG Sbjct: 1333 GGKGAKGDPGAIGAPGKTGPVGPAGPAGKPGPDGLRGLPG-SVGQQGRPGAT---GQAGP 1388 Query: 994 TRGAPTPHEKALTSPSWGKGAELLLGDQPDLIGSL----DGGAKSDSSSPNVGEFASDEV 1049 P L + KG + P LIG + + G K D P Sbjct: 1389 PGPVGPPGLPGLRGDAGAKGEK----GHPGLIGLIGPPGEQGEKGDRGLPG--------- 1435 Query: 1050 STSYANEDEVSSSSDNPQALVKASRSPLVTGSPKLPPRGVGAGEHGPKAPPPALGLGIMS 1109 S + + + P+ G P P G GPK A G G Sbjct: 1436 --------PQGSPGQKGEMGIPGASGPIGPGGPPGLP-----GPAGPKGAKGATGPG--- 1479 Query: 1110 NSTSTPDSYGGGGGPGHPGTPG 1131 G G PGHPG PG Sbjct: 1480 ---GPKGEKGVQGPPGHPGPPG 1498 Score = 85.5 bits (210), Expect = 3e-16 Identities = 159/615 (25%), Positives = 192/615 (31%), Gaps = 116/615 (18%) Query: 579 GHPGDVG-QGGLVHGGPVGGLAQPNFEREGGSTG----AGRLGTFEQQAPHLAQESAWFS 633 G PG VG QG GP+G P G G AG+ GT P A + Sbjct: 922 GPPGVVGPQGAAGETGPMGERGHPGPPGPPGEQGLPGTAGKEGTKGDPGPPGAPGKDGPA 981 Query: 634 GPHPPPGDL-LPRRMGGSGLPADCGPHDPSLAPPPPPGGSGVLFRG-PLQEPMRMPGEGH 691 G PG+ LP GG GL + GP P P PG G G P+ P R +G Sbjct: 982 GLRGFPGERGLPGTAGGPGLKGNEGPSGPP-GPAGSPGERGAAGSGGPIGPPGRPGPQGP 1040 Query: 692 VPALPSPGLQFGGSLGGLGQLQSPGAG--VGLPSAASERRPPPPDFATSALGGQPGFPFG 749 A G+ G G +G G VGLP A PP G+ G P G Sbjct: 1041 PGAAGEKGVP--GEKGPIGPTGRDGVQGPVGLPGPAG----PPGVAGEDGDKGEVGDP-G 1093 Query: 750 AAGRQSTP--HSGPGVNSPPSAGGGGGSSGGGGGGGAYPPQPDF----QPSQRTSASKLG 803 G + H PG P G G++G G GA PQ F R G Sbjct: 1094 QKGTKGNKGEHGPPGPPGPIGPVGQPGAAGADGEPGARGPQGHFGAKGDEGTRGFNGPPG 1153 Query: 804 ALSLGSFNKPSSKDNLFGQSCLAALSTACQNMIASLGAPNLNVTFNKKNPPEGKRKLSQN 863 + L PS + G + +G P PP + N Sbjct: 1154 PIGLQGLPGPSGEKGETGD-------------VGPMGPPG---------PPGPRGPAGPN 1191 Query: 864 ETDGA-------------AVAGNPGSDYFPGGTA-PGAPGPGGPSGTSSSGSKAS--GPP 907 DG G PG PG PG GP G G + GPP Sbjct: 1192 GADGPQGPPGGVGNLGPPGEKGEPGESGSPGIQGEPGVKGPRGERGEKGESGQPGEPGPP 1251 Query: 908 NP--PAQGDGTSLSPNYTLESTSGNDGKPVSGGGGRGRGRRKRDSGHV-------SPGTF 958 P P DG +P G+ G P GG RG+ K D G SPG Sbjct: 1252 GPKGPTGDDGPKGNPGPV--GFPGDPGPP-GEGGPRGQDGAKGDRGEDGEPGQPGSPGPT 1308 Query: 959 FDKYSAAPDSGGAPGVSPGQQQASGAAVGGSSAGETRGAPTPHEKALTSPSWGKGAELLL 1018 + P P SPG + G G + G+ P + P+ G Sbjct: 1309 GENGPPGPLGKRGPAGSPGSEGRQG---GKGAKGDPGAIGAPGKTGPVGPAGPAGKP--- 1362 Query: 1019 GDQPDLIGSLDGGAKSDSSSPNVGEFASDEVSTSYANEDEVSSSSDNPQALVKASRSPLV 1078 PD + L G +VG+ P A +A P Sbjct: 1363 --GPDGLRGLPG---------SVGQ-------------------QGRPGATGQAG-PPGP 1391 Query: 1079 TGSPKLPPRGVGAGEHGPKAPPPALGL------GIMSNSTSTPDSYGGGGGPGHPGTPGL 1132 G P LP AG G K P +GL P G G G G PG Sbjct: 1392 VGPPGLPGLRGDAGAKGEKGHPGLIGLIGPPGEQGEKGDRGLPGPQGSPGQKGEMGIPGA 1451 Query: 1133 EQVRTPTSSSGAPPP 1147 P G P P Sbjct: 1452 SGPIGPGGPPGLPGP 1466 Score = 79.7 bits (195), Expect = 2e-14 Identities = 246/1018 (24%), Positives = 319/1018 (31%), Gaps = 205/1018 (20%) Query: 82 GLQAQP-VHGFFGGQQPHHGHPGSHHPHQHHPHFGGNFGGPDPGASCLHGGRLLGYGGAA 140 G+ P V G G Q P GS P Q P G G PG L G + GA Sbjct: 619 GIPGPPGVRGMDGPQGPK----GSLGP-QGEPGPPGQQG--TPGTQGLPGPQ-----GAI 666 Query: 141 GGLGSQPPFAE-GYEHMAESQGPESFGPQRPGNLPDFHSSGASSHAVPAPCL--PLDQSP 197 G G + P + G M S GP P PG + G + P L P + Sbjct: 667 GPHGEKGPQGKPGLPGMPGSDGP----PGHPGKEGPPGTKGNQGPSGPQGPLGYPGPRGV 722 Query: 198 NRAASFHGLPSSSGSDSHSLEPRRVTNQGAV-DSLEYNYPG----EAPSGHFDMFSPSDS 252 GL G P + G D E PG + P G P+ Sbjct: 723 KGVDGIRGLKGHKGEKGEDGFPGFKGDIGVKGDRGEVGVPGSRGEDGPEGPKGRTGPTGD 782 Query: 253 EGQ--------------LPHYAAGRQVPGGA-----FPGASAMPRAAGMVGLSKMHAQPP 293 G LP Y GRQ P G+ FPGAS A G+ G S + Sbjct: 783 PGPPGLMGEKGKLGVPGLPGYP-GRQGPKGSLGFPGFPGASGEKGARGLSGKSGPRGERG 841 Query: 294 QQQPQQQQQPQQQQQQHGVFFERFSGARKMPVGLEPSVGSRHPLMQPPQQAPPPPQQQP- 352 P+ Q+ P+ + G P G G + P P + PP P + Sbjct: 842 PTGPRGQRGPRGATGKSGAKGTSGGDGPHGPPGERGLPGPQGPNGFPGPKGPPGPPGKDG 901 Query: 353 -PQQPPQQQ---------PPPPPGLLVRQNSCPPALPRPQQGEAGTPSGGLQDGGPMLPS 402 P P Q+ PP PPG++ Q + P ++G G P + G P Sbjct: 902 LPGHPGQRGEVGFQGKTGPPGPPGVVGPQGAAGETGPMGERGHPGPPGPPGEQGLPGTAG 961 Query: 403 QHAQFEYPIHRLENRSMHPYSEPVFSMQHPPPQQAPNQRLQHFDAPPYMNVAKRPRFDFP 462 + + P P AP + D P + FP Sbjct: 962 KEG----------------------TKGDPGPPGAPGK-----DGPAGLR-------GFP 987 Query: 463 GSAGVDRCASWNGSMHNGALDNHLSPSAYPGLPGEFTPPVPDSFPSGPPLQHPA-PDHQS 521 G G+ A G L + PS PG G +P + SG P+ P P Q Sbjct: 988 GERGLPGTAGGPG------LKGNEGPSGPPGPAG--SPGERGAAGSGGPIGPPGRPGPQG 1039 Query: 522 LQQQQQQQQQQQQQQQQQQQQQQQQQQQQRQNAALMIKQMASRNQQQRLRQPNLAQLGHP 581 ++ ++ + Q +A + + ++G P Sbjct: 1040 PPGAAGEKGVPGEKGPIGPTGRDGVQGPVGLPGPAGPPGVAGEDGDK-------GEVGDP 1092 Query: 582 GDVGQGGLV--HG-----GPVGGLAQPNFEREGGSTGA-GRLGTFEQQAPHLAQESAWFS 633 G G G HG GP+G + QP G GA G G F + + + F+ Sbjct: 1093 GQKGTKGNKGEHGPPGPPGPIGPVGQPGAAGADGEPGARGPQGHFGAKGD---EGTRGFN 1149 Query: 634 GPHPPPG-DLLPRRMGGSGLPADCGPHDPSLAPPP--------------PPGGSGVLFRG 678 GP P G LP G G D GP P P P PPGG G L G Sbjct: 1150 GPPGPIGLQGLPGPSGEKGETGDVGPMGPPGPPGPRGPAGPNGADGPQGPPGGVGNL--G 1207 Query: 679 PLQEPMRMPGEGHVPALPS-PGLQFG----GSLGGLGQLQSPGAG--------------- 718 P E PGE P + PG++ G G GQ PG Sbjct: 1208 PPGEKGE-PGESGSPGIQGEPGVKGPRGERGEKGESGQPGEPGPPGPKGPTGDDGPKGNP 1266 Query: 719 -----VGLPSAASERRPPPPDFATSALG-----GQPGFP-----------FGAAGRQSTP 757 G P E P D A G GQPG P G G +P Sbjct: 1267 GPVGFPGDPGPPGEGGPRGQDGAKGDRGEDGEPGQPGSPGPTGENGPPGPLGKRGPAGSP 1326 Query: 758 HS-----GPGVNSPPSAGGGGGSSGG-GGGGGAYPPQPDFQ---PSQRTSASKLGALSLG 808 S G G P A G G +G G G A P PD P + GA Sbjct: 1327 GSEGRQGGKGAKGDPGAIGAPGKTGPVGPAGPAGKPGPDGLRGLPGSVGQQGRPGATGQA 1386 Query: 809 SFNKPSSKDNLFGQSCLAALS--TACQNMIASLGAPNLNVTFNKKNPPEGKRKLSQNETD 866 P L G A +I +G P + P + Q Sbjct: 1387 GPPGPVGPPGLPGLRGDAGAKGEKGHPGLIGLIGPPGEQGEKGDRGLPGPQGSPGQKGEM 1446 Query: 867 GAAVAGNPGSDYFPGGTAPGAPGPGGPSGTSSSGSKASGPPNPPAQGDGTSLSPNYTLES 926 G A P PGG PG PGP GP G A+GP P + ++ Sbjct: 1447 GIPGASGPIG---PGGP-PGLPGPAGPKGAKG----ATGPGGPKGEKG---------VQG 1489 Query: 927 TSGNDGKPVSGGGGRGRGRRKRDSGHVSPGTFFDKYSAAPDSGGAPGVSPGQQQASGA 984 G+ G P K+ V + A P +GGAPG G ++ G+ Sbjct: 1490 PPGHPGPPGEVIQPLPIQMPKKTRRSVDGSRLMQEDEAIP-TGGAPGSPGGLEEIFGS 1546 Score = 48.9 bits (115), Expect = 3e-05 Identities = 91/381 (23%), Positives = 128/381 (33%), Gaps = 71/381 (18%) Query: 868 AAVAGNPGSDYFPGGTA-PGAPGPGGPSGTSSSGSKASGPPNPPAQGDGTSLSPNYTLES 926 A + G PG PG PG GP G +G S G P PP GTSL + S Sbjct: 407 AGLIGPPGIQGNPGPVGDPGERGPPGRAGLPGS----DGAPGPP----GTSLMLPFRFGS 458 Query: 927 TSGNDGKPVSGGGGRGRG--RRKRDSGHVSPGTFFDKYSAAPDSGGAPGVSPGQQQASGA 984 G+ G V+ + + ++ R + PG Y+ P G PG SPG + SG Sbjct: 459 GGGDKGPVVAAQEAQAQAILQQARLALRGPPGPM--GYTGRPGPLGQPG-SPGLKGESGD 515 Query: 985 AVGGSSAGETRGAPTPHEKALTSPSWGKGAELLLGDQPDLIGS--LDGGAKSDSSSPNVG 1042 G P + + GA + GD P + G DG + G Sbjct: 516 LGPQGPRGPQGLTGPPGKAGRRGRAGADGARGMPGD-PGVKGDRGFDGLPGLPGEKGHRG 574 Query: 1043 EFASDEVSTSYANEDEVSSSSD----------NPQALVKASRSPLVTGSPKL-------- 1084 + + + + E + P+ L+ P + G P + Sbjct: 575 DTGAQGLPGPPGEDGERGDDGEIGPRGLPGESGPRGLLGPKGPPGIPGPPGVRGMDGPQG 634 Query: 1085 ------------PPRGVGA-------------GEHGPKAPPPALGLGIMSNSTSTPDSYG 1119 PP G G HG K P GL M S P G Sbjct: 635 PKGSLGPQGEPGPPGQQGTPGTQGLPGPQGAIGPHGEKGPQGKPGLPGMPGSDGPP---G 691 Query: 1120 GGGGPGHPGTPGLEQVRTPTSSSGAPPPDEIHPLEILQAQIQLQRQQFSISEDQPLGLKG 1179 G G PGT G + P G P P + ++ ++ L+ + ED G KG Sbjct: 692 HPGKEGPPGTKGNQGPSGPQGPLGYPGPRGVKGVDGIRG---LKGHKGEKGEDGFPGFKG 748 Query: 1180 -----GKKGECAVGASGAQNG 1195 G +GE V S ++G Sbjct: 749 DIGVKGDRGEVGVPGSRGEDG 769 Score = 47.4 bits (111), Expect = 9e-05 Identities = 147/688 (21%), Positives = 206/688 (29%), Gaps = 150/688 (21%) Query: 519 HQSLQQQQQQQQQQQQQQQQQQQQQQQQQQQQRQNAALMIKQMASRNQQQRLRQPNLAQL 578 ++S +Q++ + + Q+++ Q QQ + Q+ Q+Q + L R Q Q + L Sbjct: 218 YESCEQKELECEGGQRERPQNQQPHRAQRSPQQQPSRL------HRPQNQEPQSQPTESL 271 Query: 579 GHPGDVGQGGLVHGGPVGGLAQPNFEREGGSTGAGRLGTFEQQAPHLAQESAWFSGPHPP 638 + + ++ G P E + L E++ L PP Sbjct: 272 YYDYEPPYYDVMTTGTTPDYQDPTPGEEEEILESSLLPPLEEEQTDLQV---------PP 322 Query: 639 PGDLLP-RRMGGSGLPADCGPHD----------------PSLAPPPPPGGSGVLFRGPLQ 681 D G G GP+D P+L+ G+ Sbjct: 323 TADRFQAEEYGEGGTDPPEGPYDYTYGYGDDYREETELGPALSAETAHSGAAA------H 376 Query: 682 EPMRMPGEGHVPALPSPGLQFGGSLGGLGQLQSPGAGVGLPSAASERRPPPPDFATSALG 741 P + GE PA+ PG+ G G G P +G P + Sbjct: 377 GPRGLKGEKGEPAVLEPGMLVEGPPGPEG----PAGLIGPPG----------------IQ 416 Query: 742 GQPGFPFGAAGRQSTPHSGPGVNSPPSAGGGGGSSGG--------------GGGGGAYPP 787 G PG P PG PP G GS G G GGG P Sbjct: 417 GNPG-----------PVGDPGERGPPGRAGLPGSDGAPGPPGTSLMLPFRFGSGGGDKGP 465 Query: 788 QPDFQPSQRTSASKLGALSLGSFNKP---SSKDNLFGQSCLAALSTACQNMIASLGAPNL 844 Q +Q + + L+L P + + GQ S + LG Sbjct: 466 VVAAQEAQAQAILQQARLALRGPPGPMGYTGRPGPLGQPG----SPGLKGESGDLGPQGP 521 Query: 845 NVTFNKKNPPEGKRKLSQNETDGA-------AVAGNPGSDYFPGGTAPGAPGPGGPSGTS 897 PP + + DGA V G+ G D PG PG G G +G Sbjct: 522 RGPQGLTGPPGKAGRRGRAGADGARGMPGDPGVKGDRGFDGLPG--LPGEKGHRGDTG-- 577 Query: 898 SSGSKASGPPNPPAQ----GDGTSLSPNYTLESTS-----GNDGKPVSGG--GGRGRGRR 946 A G P PP + GD + P + G G P G G RG Sbjct: 578 -----AQGLPGPPGEDGERGDDGEIGPRGLPGESGPRGLLGPKGPPGIPGPPGVRGMDGP 632 Query: 947 KRDSGHVSPGTFFDKYSAAPDSGGAPGVS--PGQQQASG--AAVGGSSAGETRGAP---- 998 + G + P P G PG PG Q A G G G P Sbjct: 633 QGPKGSLGP----QGEPGPPGQQGTPGTQGLPGPQGAIGPHGEKGPQGKPGLPGMPGSDG 688 Query: 999 TPHEKALTSPSWGKGAELLLGDQPDLIGSLDGGAKSDSSSPNVGEFASDEVSTSYAN-ED 1057 P P KG + G Q L G K + ++ + + Sbjct: 689 PPGHPGKEGPPGTKGNQGPSGPQGPLGYPGPRGVKGVDGIRGLKGHKGEKGEDGFPGFKG 748 Query: 1058 EVSSSSDNPQALVKASRSPLVTGSPKLPPRGVGAGEHGPKAPPPALGLGIMSNSTSTPDS 1117 ++ D + V SR GE GP+ P G + P Sbjct: 749 DIGVKGDRGEVGVPGSR-----------------GEDGPEGPKGRTG---PTGDPGPPGL 788 Query: 1118 YGGGGGPGHPGTPGLEQVRTPTSSSGAP 1145 G G G PG PG + P S G P Sbjct: 789 MGEKGKLGVPGLPGYPGRQGPKGSLGFP 816 Score = 40.4 bits (93), Expect = 0.011 Identities = 97/381 (25%), Positives = 122/381 (32%), Gaps = 73/381 (19%) Query: 37 PAFHTGGPPGPVDPAMSALGEPPILGMNMEPYGFHARGHSELHAGGLQAQPVHGFFGGQQ 96 P GPPGP PA +G P I G N P G G + P G Sbjct: 393 PGMLVEGPPGPEGPA-GLIGPPGIQG-NPGPVG----------DPGERGPPGRAGLPGSD 440 Query: 97 PHHGHPGSHHPHQHHPHFGGNFGGPDPGA------SCLHGGRL--------LGYGGAAGG 142 G PG+ GG GP A + L RL +GY G G Sbjct: 441 GAPGPPGTSLMLPFRFGSGGGDKGPVVAAQEAQAQAILQQARLALRGPPGPMGYTGRPGP 500 Query: 143 LGSQP--PFAEGYEHMAESQGPESFGPQRPGNLPDFHSSGASSHAVPAPCLPLDQSPNRA 200 LG QP P +G QGP GPQ P + A A +P D Sbjct: 501 LG-QPGSPGLKGESGDLGPQGPR--GPQGLTGPPGKAGRRGRAGADGARGMPGDPGVKGD 557 Query: 201 ASFHGLPSSSGSDSHSLEPRRVTNQGAVDSLEYNYPGEAPSGHFDMFSPSDSEGQL-PHY 259 F GLP G H D+ PG P G +G++ P Sbjct: 558 RGFDGLPGLPGEKGH-----------RGDTGAQGLPG--PPGE---DGERGDDGEIGPRG 601 Query: 260 AAGRQVPGGAF--PGASAMPRAAGMVGLSKMHAQPPQQQPQQQQQPQQQQQQHGVFFERF 317 G P G G +P G+ G+ PQ + P QQ Sbjct: 602 LPGESGPRGLLGPKGPPGIPGPPGVRGMDGPQGPKGSLGPQGEPGPPGQQGT-------- 653 Query: 318 SGARKMPVGLEPSVGSRHPLMQPPQQAPPPPQQQPPQQPPQQQPPPPPGLLVRQNSCPPA 377 G + +P G + ++G P + P + P P PP PG PP Sbjct: 654 PGTQGLP-GPQGAIG-------PHGEKGPQGKPGLPGMPGSDGPPGHPG-----KEGPPG 700 Query: 378 LPRPQQGEAGTPSGGLQDGGP 398 + QG +G P G L GP Sbjct: 701 -TKGNQGPSG-PQGPLGYPGP 719 Score = 31.2 bits (69), Expect = 6.9 Identities = 39/147 (26%), Positives = 56/147 (38%), Gaps = 16/147 (10%) Query: 1061 SSSDNPQALVKASRSPLVTGSPKLPPRGVGAGEHGPKAPPPALGL-GIMSNSTSTPDSYG 1119 +++ P+ L P V L P + G GP+ P +G GI N D G Sbjct: 373 AAAHGPRGLKGEKGEPAV-----LEPGMLVEGPPGPEGPAGLIGPPGIQGNPGPVGDP-G 426 Query: 1120 GGGGPGHPGTPGLEQVRTPTSSS-------GAPPPDEIHPLEILQAQIQLQRQQFSISED 1172 G PG G PG + P +S G+ D+ + +AQ Q QQ ++ Sbjct: 427 ERGPPGRAGLPGSDGAPGPPGTSLMLPFRFGSGGGDKGPVVAAQEAQAQAILQQARLALR 486 Query: 1173 QPLGLKG--GKKGECAVGASGAQNGDS 1197 P G G G+ G S G+S Sbjct: 487 GPPGPMGYTGRPGPLGQPGSPGLKGES 513 >gi|40068462 AT rich interactive domain 1B (SWI1-like) isoform 3 [Homo sapiens] Length = 2178 Score = 96.7 bits (239), Expect = 1e-19 Identities = 232/980 (23%), Positives = 316/980 (32%), Gaps = 236/980 (24%) Query: 44 PPGPVDPAMSALGE----PPILGMNMEPYGFHARGHSELHAGGLQAQPV----------- 88 PPGP P +S G+ PP +G EP G H L A G Q PV Sbjct: 115 PPGP--PLLSKPGDEDDAPPKMG---EPAGGRYE-HPGLGALGTQQPPVAVPGGGGGPAA 168 Query: 89 ----HGFFGGQQPHHGHPGSHHPHQHHPHFGGNFGGPDPGASCLHGGRLLGYGGAAGGLG 144 + ++G P G PG + P F + G PG +H AAG G Sbjct: 169 VPEFNNYYGSAAPASGGPGG----RAGPCFDQHGGQQSPGMGMMHSAS----AAAAGAPG 220 Query: 145 SQPPFAEGYEHMAESQGPESFGPQRPGNLPDFHSSGASSHAVPAPCLPLDQSPNRAASFH 204 S P +E SQ G RPG G + Sbjct: 221 SMDPLQNSHEGYPNSQCNHYPGYSRPGAGGGGGGGGGGGGG------------SGGGGGG 268 Query: 205 GLPSSSGSDSHSLEPRRVTNQGAVDSLEYNYPGEAPSGHFDMFSPSDSEGQLPHYAAGRQ 264 G + G+ + ++ A G + +G+ + SP RQ Sbjct: 269 GGAGAGGAGAGAVAAAAAAAAAAAGGGGGGGYGGSSAGYGVLSSP-------------RQ 315 Query: 265 VPGGAFPGASAMPRAAGMVGLSKMHAQPPQQQPQQQQQPQQQQQQHGVFFERFSGARKMP 324 GG G P G LSK A F+RF+G + P Sbjct: 316 QGGGMMMG----PGGGGAASLSKAAAGSAAGG-----------------FQRFAGQNQHP 354 Query: 325 VGLEPSVGSRHPLMQPPQQAPPPPQQQPPQQPPQQQPPPPPGLLVRQNSCPPALPRPQQG 384 G P++ L+ P P + P P PP PP+ P+ Q Sbjct: 355 SGATPTLNQ---LLTSPS---PMMRSYGGSYPEYSSPSAPPP--------PPSQPQSQAA 400 Query: 385 EAGTPSGGLQDGGPMLPSQHAQFEYPIHRLENRSMHPYSEPVFSMQHPPPQQAPNQRLQH 444 AG +GG Q M + +Y + S P S P P +Q Sbjct: 401 AAGAAAGGQQAAAGMGLGKDMGAQYAAASPAWAAAQQRSHPAMSPGTPGPTMGRSQ---- 456 Query: 445 FDAPPYMNVAKRPRFDFPGSAGVDRCASWNGSMHNGALDNHLSP---SAYPGLPGEFTPP 501 +P V KRP+ GS + H P S YPG G + PP Sbjct: 457 -GSPMDPMVMKRPQLYGMGS------------------NPHSQPQQSSPYPG--GSYGPP 495 Query: 502 VPDSFPSGPPLQHPAPDHQSLQQQQQQQQQQQQQQQ------QQQQQQQQQQQQQRQNAA 555 P +P G +Q P + Q QQQ Q QQ QQ QQ QQ Q + Sbjct: 496 GPQRYPIG--IQGRTPGAMAGMQYPQQQMPPQYGQQGVSGYCQQGQQPYYSQQPQPPHLP 553 Query: 556 LMIKQMASRNQQQRLRQPNLAQLGH---------PGDVGQ-----------------GGL 589 + + S++QQ+ Q +++Q G+ PG G Sbjct: 554 PQAQYLPSQSQQRYQPQQDMSQEGYGTRSQPPLAPGKPNHEDLNLIQQERPSSLPDLSGS 613 Query: 590 VHGGPVGGLAQ-PNFEREGGSTGAGRLGTFEQQAPHLAQESAWFS----GPHPPP-GDLL 643 + P G A + GST + + Q+P S S GP P P G + Sbjct: 614 IDDLPTGTEATLSSAVSASGSTSSQGDQSNPAQSPFSPHASPHLSSIPGGPSPSPVGSPV 673 Query: 644 PRRMGGSGLPADCGPHDPSLAPPPPPGGSG------VLFRGPL-QEPMRMPGEGHVPAL- 695 SG P S PP PPG L + P+ QE M G P + Sbjct: 674 GSNQSRSG-PISPASIPGSQMPPQPPGSQSESSSHPALSQSPMPQERGFMAGTQRNPQMA 732 Query: 696 --------------PSPGLQFGGSL-------------------GGLGQLQSPGAGVGLP 722 PSPG Q + G G P A G+P Sbjct: 733 QYGPQQTGPSMSPHPSPGGQMHAGISSFQQSNSSGTYGPQMSQYGPQGNYSRPPAYSGVP 792 Query: 723 SAASERRPPPPDFATSA---LGGQ-PGFPFGA--------AGRQSTPHSGPGVNSPPSAG 770 SA+ P P SA + GQ P P GA AG Q+ P G + PS+ Sbjct: 793 SASYS--GPGPGMGISANNQMHGQGPSQPCGAVPLGRMPSAGMQNRPFPGNMSSMTPSSP 850 Query: 771 GGGGSSGGGGGGGAYPPQPDF-QPSQRTSASKLGALSLGSFNKPSSKDNLFGQSCLAALS 829 G G G G PP P + +Q +A+ + A + + ++ S + +A+ S Sbjct: 851 GMSQQGGPGMG----PPMPTVNRKAQEAAAAVMQAAANSAQSRQGSFPGMNQSGLMASSS 906 Query: 830 TACQNMIASLGAPNLNVTFNKKNPPEGKRKLSQNETD---GAAVAGNPGSDYFP-----G 881 Q M N + N + PP N + G A +PG P Sbjct: 907 PYSQPM------NNSSSLMNTQAPPYSMAPAMVNSSAASVGLADMMSPGESKLPLPLKAD 960 Query: 882 GTAPGAPGPGGPSGTSSSGS 901 G G P P S SSS + Sbjct: 961 GKEEGTPQPESKSKKSSSST 980 Score = 95.1 bits (235), Expect = 4e-19 Identities = 168/663 (25%), Positives = 217/663 (32%), Gaps = 145/663 (21%) Query: 514 HPAPDHQSLQQQQQQQQQQQQQQQQQQQQQQQQQQQQRQNAALMIKQMASRNQQQRLRQP 573 H H +LQQQ Q QQQQQQQQQQQQQQQQQQ N +L Sbjct: 40 HHLHHHHALQQQLNQFQQQQQQQQQQQQQQQQQQHPISNNNSL----------------- 82 Query: 574 NLAQLGHPGDVGQGGLVHGGPVGGLAQPNFERE----GGSTGAGRLGTFEQQAPHLAQES 629 GG GG QP + E GG+ + G + P L + Sbjct: 83 ------------------GGAGGGAPQPGPDMEQPQHGGAKDSAAGGQADPPGPPLLSKP 124 Query: 630 AWFSGPHPPPGDLLPRRMGGSGLPADCGPHDPSLAPPPPPGGSGVLFRGPLQEPMRMPGE 689 P G+ R GL A G P P PGG G GP P Sbjct: 125 GDEDDAPPKMGEPAGGRYEHPGLGA-LGTQQP---PVAVPGGGG----GPAAVPEFNNYY 176 Query: 690 GH-VPALPSPGLQFGGSLGGLGQLQSPGAG-VGLPSAASERRPPPPDFATSALGGQPGFP 747 G PA PG + G G QSPG G + SAA+ P D ++ G P Sbjct: 177 GSAAPASGGPGGRAGPCFDQHGGQQSPGMGMMHSASAAAAGAPGSMDPLQNSHEGYPNSQ 236 Query: 748 FGAAGRQSTPHSGPGVNSPPSAGGGGGSSGGGGGGGAYPPQPDFQPSQRTSASKLGALSL 807 S P +G G GGGGGS GGGGGGGA GA Sbjct: 237 CNHYPGYSRPGAGGGGGG--GGGGGGGSGGGGGGGGA------------------GAGGA 276 Query: 808 GSFNKPSSKDNLFGQSCLAALSTACQNMIASLGAPNLNVTFNKKNPPEGKRKLSQNETDG 867 G+ A++ A A+ G G + G Sbjct: 277 GA----------------GAVAAAAAAAAAAAGG--------------GGGGGYGGSSAG 306 Query: 868 AAVAGNPGSDYFPGGTAPGAPGPGGPSGTS--SSGSKASGPPNPPAQGDGTS-LSPNYTL 924 V +P GG PG GG + S ++GS A G Q S +P Sbjct: 307 YGVLSSPRQQ---GGGMMMGPGGGGAASLSKAAAGSAAGGFQRFAGQNQHPSGATPTLNQ 363 Query: 925 ESTSGNDGKPVSGGGGRGRGRRKRDSGHVSPGTFFDKYSAAPDSGGAPGVSPGQQQASGA 984 TS + GG + +YS+ P Q A+GA Sbjct: 364 LLTSPSPMMRSYGGS-------------------YPEYSSPSAPPPPPSQPQSQAAAAGA 404 Query: 985 AVGG--SSAGETRGAPTPHEKALTSPSWGKGAELLLGDQPDLIGSLDGGAKSDSSSPNVG 1042 A GG ++AG G + A SP+W + P + G P +G Sbjct: 405 AAGGQQAAAGMGLGKDMGAQYAAASPAWAAAQQ---RSHPAMSPGTPG--------PTMG 453 Query: 1043 EFASDEVSTSYANEDEVSSSSDNPQALVKASRSPLVTGSPKLPPRGVGAGEHGPKAPPPA 1102 + ++ NP + + S SP GS P G G + P Sbjct: 454 RSQGSPMDPMVMKRPQLYGMGSNPHSQPQQS-SPYPGGS--YGPPGPQRYPIGIQGRTPG 510 Query: 1103 LGLGIMSNSTSTPDSYGGGGGPGHPGTPGLEQVRTPTSSSGAPPPDEIHPLEILQAQIQL 1162 G+ P YG G G+ +Q + P S PP + L +Q Q Sbjct: 511 AMAGMQYPQQQMPPQYGQQGVSGY-----CQQGQQPYYSQQPQPPHLPPQAQYLPSQSQQ 565 Query: 1163 QRQ 1165 + Q Sbjct: 566 RYQ 568 Score = 82.8 bits (203), Expect = 2e-15 Identities = 181/796 (22%), Positives = 249/796 (31%), Gaps = 114/796 (14%) Query: 31 NTHFKAPAFHTGGPPGPVDPAMSALGEPPILGMNMEPYGFHARGHSELHAGGLQAQPVHG 90 N ++ + A +GGP G P G GM M +H+ A G Sbjct: 173 NNYYGSAAPASGGPGGRAGPCFDQHGGQQSPGMGM------------MHSASAAAAGAPG 220 Query: 91 FFGG-QQPHHGHPGS---HHPHQHHPHFGGNFGGPDPGASCLHGGRLLGYGGAAG-GLGS 145 Q H G+P S H+P P GG GG G GG G GA G G G+ Sbjct: 221 SMDPLQNSHEGYPNSQCNHYPGYSRPGAGGGGGGGGGGGGGSGGGGGGGGAGAGGAGAGA 280 Query: 146 QPPFAEGYEHMAESQGPESFGPQRPG----NLPDFHSSGASSHAVPAPCLPLDQSPNRAA 201 A A G +G G + P G L ++ +A Sbjct: 281 VAAAAAAAAAAAGGGGGGGYGGSSAGYGVLSSPRQQGGGMMMGPGGGGAASLSKAAAGSA 340 Query: 202 SFHGLPSSSGSDSHSLEPRRVTNQ--GAVDSLEYNYPGEAPSGHFDMFSPSDSEGQLPHY 259 + G +G + H NQ + + +Y G P + +P Q Sbjct: 341 A-GGFQRFAGQNQHPSGATPTLNQLLTSPSPMMRSYGGSYPE-YSSPSAPPPPPSQPQSQ 398 Query: 260 AAGRQVPGGAFPGASAMPRAAGMVGLSKMHAQPPQQQPQQQQQPQQQQQQHGVFFERFSG 319 AA G A+ M M G A P QQ+ P G R G Sbjct: 399 AAAAGAAAGGQQAAAGMGLGKDM-GAQYAAASPAWAAAQQRSHPAMSPGTPGPTMGRSQG 457 Query: 320 ARKMPVGLEP----SVGSRHPLMQPPQQA--------PPPPQQQP------------PQQ 355 + P+ ++ +GS +P QP Q + PP PQ+ P Q Sbjct: 458 SPMDPMVMKRPQLYGMGS-NPHSQPQQSSPYPGGSYGPPGPQRYPIGIQGRTPGAMAGMQ 516 Query: 356 PPQQQPPPPPGLLVRQNSCPPALPRPQQGEAGTPSGGLQDGGPMLPSQHAQFEYPIHRLE 415 PQQQ PP G C +P + P L LPSQ Q P + Sbjct: 517 YPQQQMPPQYGQQGVSGYCQQG-QQPYYSQQPQPP-HLPPQAQYLPSQSQQRYQPQQDMS 574 Query: 416 NRSMHPYSEPVFS-----------MQHPPPQQAPNQRLQHFDAPPYMNVAKRPRFDFPGS 464 S+P + +Q P P+ D P GS Sbjct: 575 QEGYGTRSQPPLAPGKPNHEDLNLIQQERPSSLPDLSGSIDDLPTGTEATLSSAVSASGS 634 Query: 465 AGVDRCASWNGSMHNGA---LDNHLSP--SAYPGLPGEFTPPVPDSFPSGPPLQHPAP-D 518 S G N A H SP S+ PG P P P P G P Sbjct: 635 ------TSSQGDQSNPAQSPFSPHASPHLSSIPGGPS----PSPVGSPVGSNQSRSGPIS 684 Query: 519 HQSLQQQQQQQQQQQQQQQQQQQQQQQQQQQQRQNAALMIKQMASRNQQQRLRQPNLAQL 578 S+ Q Q Q + Q ++ + Q + Q +Q + Sbjct: 685 PASIPGSQMPPQPPGSQSESSSHPALSQSPMPQERGFMAGTQRNPQMAQYGPQQTGPSMS 744 Query: 579 GHPGDVGQGGLVHGGPVGGLAQPNFEREGG--STGAGRLGTFEQQAPHLAQESAWFSGPH 636 HP GG +H G + Q N G + G G + + + SA +SGP Sbjct: 745 PHP---SPGGQMHAG-ISSFQQSNSSGTYGPQMSQYGPQGNYSRPPAYSGVPSASYSGPG 800 Query: 637 PPPGDLLPRRMGGSGLPADCGPHDPSLAPPPPPGGSGVLFRGPLQEPMRMPGEGHVPALP 696 P G +M G G P P G+ L R P P G++ ++ Sbjct: 801 PGMGISANNQMHGQG--------------PSQPCGAVPLGRMPSAGMQNRPFPGNMSSMT 846 Query: 697 SPGLQFGGSLGGLGQLQSPGAGVGLPS-------AASERRPPPPDFATSALGGQPGFPFG 749 S G+ Q PG G +P+ AA+ + A S G PG Sbjct: 847 P-------SSPGMSQQGGPGMGPPMPTVNRKAQEAAAAVMQAAANSAQSRQGSFPGMNQS 899 Query: 750 AAGRQSTPHSGPGVNS 765 S+P+S P NS Sbjct: 900 GLMASSSPYSQPMNNS 915 Score = 68.2 bits (165), Expect = 5e-11 Identities = 125/504 (24%), Positives = 179/504 (35%), Gaps = 69/504 (13%) Query: 703 GGSLGGLGQ----LQSPGAGVGLPSAASERRPPPPDFATSALGGQPGFP----FGAAGRQ 754 GG+ GG Q ++ P G SAA + PP S G + P A GR Sbjct: 83 GGAGGGAPQPGPDMEQPQHGGAKDSAAGGQADPPGPPLLSKPGDEDDAPPKMGEPAGGRY 142 Query: 755 STPHSGP-GVNSPPSAGGGGGSSGGGGGGGAYPPQPDFQPSQRTSASKLGALSLGSFNKP 813 P G G PP A GGGGG A P ++ S ++ G + F++ Sbjct: 143 EHPGLGALGTQQPPVA-----VPGGGGGPAAVPEFNNYYGSAAPASGGPGGRAGPCFDQH 197 Query: 814 SSKDNLFGQSCLAALSTACQNMIASLGAPNLNVTFNKKNPPEGKRKLSQNETDGAAVAGN 873 + + G + + S A + GAP G QN +G N Sbjct: 198 GGQQSP-GMGMMHSASAA------AAGAP-------------GSMDPLQNSHEGYP---N 234 Query: 874 PGSDYFPGGTAPGAPGPGGPSGTSSSGSKASGPPNPPAQGDGTSLSPNYTLESTSGNDGK 933 +++PG + PGA G GG G GS G G G + + + + Sbjct: 235 SQCNHYPGYSRPGAGGGGGGGGGGGGGSGGGGGGG----GAGAGGAGAGAVAAAAAAAAA 290 Query: 934 PVSGGGGRGRGRRKRDSGHVS-PGTFFDKYSAAPDSGGAPGVSPGQQQASGAAVGGSS-- 990 GGGG G G G +S P P GGA +S + A+G+A GG Sbjct: 291 AAGGGGGGGYGGSSAGYGVLSSPRQQGGGMMMGPGGGGAASLS---KAAAGSAAGGFQRF 347 Query: 991 AGETR---GAPTPHEKALTSPS---WGKGAELLLGDQPDLIGSLDGGAKSDSSSPNVGEF 1044 AG+ + GA + LTSPS G P +S +++ Sbjct: 348 AGQNQHPSGATPTLNQLLTSPSPMMRSYGGSYPEYSSPSAPPPPPSQPQSQAAAAGAAAG 407 Query: 1045 ASDEVSTSYANEDEVSSSSDNPQALVKASRSPLVTGSPKLPPRGVGAGEHGPKAP----- 1099 + +D + + A A + SP P +G + P P Sbjct: 408 GQQAAAGMGLGKDMGAQYAAASPAWAAAQQRSHPAMSPGTPGPTMGRSQGSPMDPMVMKR 467 Query: 1100 PPALGLGIMSNSTSTPDS---YGGG--GGPGHPGTPGLEQVRTPTSSSGAPPPDEIHPLE 1154 P G+G SN S P Y GG G PG P Q RTP + +G P + P + Sbjct: 468 PQLYGMG--SNPHSQPQQSSPYPGGSYGPPGPQRYPIGIQGRTPGAMAGMQYPQQQMPPQ 525 Query: 1155 ILQAQI----QLQRQQFSISEDQP 1174 Q + Q +Q + + QP Sbjct: 526 YGQQGVSGYCQQGQQPYYSQQPQP 549 Score = 56.2 bits (134), Expect = 2e-07 Identities = 109/462 (23%), Positives = 164/462 (35%), Gaps = 81/462 (17%) Query: 95 QQPHHGHPGSHHPHQHHPHFGGNFGGPDPG-------ASCLHGGRLLGYGGAAGGLGSQP 147 Q P + GS Q G N PG AS HG GG + + Sbjct: 1108 QPPSPANSGSLQGPQTPQSTGSNSMAEVPGDLKPPTPASTPHGQMTPMQGGRSSTISVHD 1167 Query: 148 PFAEGYEHMAESQGPE--SFGPQRPGNLPDFHSSGASSHAVPAPCLPLDQSPNRAASFHG 205 PF++ +++S P+ S P P + G S +P + PN+ F G Sbjct: 1168 PFSD----VSDSSFPKRNSMTPNAP------YQQGMS---MPDVMGRMPYEPNKDP-FGG 1213 Query: 206 LPSSSGSDSHSLEPRRVTNQGAVDSLEYNYPGEAPSGHFDMFSPSDSEGQLPHYAA---- 261 + GS + ++ N D YN ++PSG + Q P+ A+ Sbjct: 1214 MRKVPGSSEPFMTQGQMPNSSMQDM--YN---QSPSGAMSNLGMGQRQ-QFPYGASYDRR 1267 Query: 262 ----GRQVPGGAFPGASAMPRAAGMVGLS------KMHAQ----PPQQQPQ----QQQQP 303 G+Q PG P + P GL K H PP ++ + Q Sbjct: 1268 HEPYGQQYPGQG-PPSGQPPYGGHQPGLYPQQPNYKRHMDGMYGPPAKRHEGDMYNMQYS 1326 Query: 304 QQQQQQHGVFFERFSGARKMPV-GLEPSVGSRHPLMQPPQ---QAPPPPQQQPPQQPPQQ 359 QQQ+ + + +SG + P+ G P SR + P Q PP P Q Sbjct: 1327 SQQQEMYNQYGGSYSGPDRRPIQGQYPYPYSRERMQGPGQIQTHGIPPQMMGGPLQSSSS 1386 Query: 360 QPPPPPGLLVRQNSCPPALPRPQQGEAGTPSGGLQDGGPMLPSQHAQFEY--PIHRLENR 417 + P R + +P P Q G P G Q P P + + P R+ + Sbjct: 1387 EGPQQNMWAARND-----MPYPYQNRQG-PGGPTQ--APPYPGMNRTDDMMVPDQRINHE 1438 Query: 418 SMHPYSEPVFSMQHPPPQQAPNQRLQHFDAPPYMNVAKRPRFDFPGSAGVDRCASWNGSM 477 S P + P + + +Q PP +P + P S + + + Sbjct: 1439 SQWPSH-----VSQRQPYMSSSASMQPITRPP------QPSYQTPPSLPNHISRAPSPAS 1487 Query: 478 HNGALDNHLSPSAYPGLPG----EFTPPVPDSFPSGPPLQHP 515 +L+N +SPS P LP + P VP S +GPP Q P Sbjct: 1488 FQRSLENRMSPSKSPFLPSMKMQKVMPTVPTSQVTGPPPQPP 1529 Score = 53.9 bits (128), Expect = 1e-06 Identities = 206/912 (22%), Positives = 263/912 (28%), Gaps = 191/912 (20%) Query: 335 HPLMQPPQQAPPPPQQQPPQQPPQQQPPPPPGLLVRQNSCPPALPRPQQGEAGTPSGGLQ 394 H L Q Q QQQ QQ QQQ P + NS G GG Sbjct: 46 HALQQQLNQFQQQQQQQQQQQQQQQQQQHP---ISNNNSL------------GGAGGGAP 90 Query: 395 DGGPMLPSQHAQFEYPIHRLENRSMHPYSEPVFSMQHPPPQQAPNQRLQHFDAPPYMNVA 454 GP E P H S PP ++ DAPP M Sbjct: 91 QPGP-------DMEQPQHGGAKDSA------AGGQADPPGPPLLSKPGDEDDAPPKMGEP 137 Query: 455 KRPRFDFPGSAGVDRCASWNGSMHNGALDNHLSPSAYPGLPG--EFTPPVPDSFPSGPPL 512 R++ PG GAL P A PG G P + + S P Sbjct: 138 AGGRYEHPGL---------------GALGTQQPPVAVPGGGGGPAAVPEFNNYYGSAAPA 182 Query: 513 QHPAPDHQSLQQQQQQQQQQQQQQQQQQQQQQQQQQQQRQNAALMIKQMASRNQQQRLRQ 572 P ++ Q QQ L N Q Sbjct: 183 SG-GPGGRAGPCFDQHGGQQSPGMGMMHSASAAAAGAPGSMDPLQNSHEGYPNSQCN-HY 240 Query: 573 PNLAQLGHPGDVGQGGLVHGGPVGGLAQPNFEREGGSTGAGRLGTFEQQAPHLAQESA-- 630 P ++ G G G GG GG GG GG GAG G A A +A Sbjct: 241 PGYSRPGAGGGGGGGGGGGGGSGGGGG-------GGGAGAGGAGAGAVAAAAAAAAAAAG 293 Query: 631 -----WFSGPHPPPGDLLPRRMGGSGL---PADCGPHDPSLAPPPPPGGSGVLFRGPLQE 682 + G G L R G G+ P G S A G F G Q Sbjct: 294 GGGGGGYGGSSAGYGVLSSPRQQGGGMMMGPGGGGAASLSKAAAGSAAGGFQRFAGQNQH 353 Query: 683 PM-RMPGEGHVPALPSPGLQ-FGGSL-----------------------GGLGQLQSPGA 717 P P + PSP ++ +GGS G Q A Sbjct: 354 PSGATPTLNQLLTSPSPMMRSYGGSYPEYSSPSAPPPPPSQPQSQAAAAGAAAGGQQAAA 413 Query: 718 GVGLPS-------------AASERRPPP---PDFATSALGGQPGFPFGAA--------GR 753 G+GL AA+++R P P +G G P G Sbjct: 414 GMGLGKDMGAQYAAASPAWAAAQQRSHPAMSPGTPGPTMGRSQGSPMDPMVMKRPQLYGM 473 Query: 754 QSTPHSGPGVNSPPSAGGGG------------GSSGGGGGGGAYPPQPDFQPSQRTSASK 801 S PHS P +SP G G G + G G YP Q P Q Sbjct: 474 GSNPHSQPQQSSPYPGGSYGPPGPQRYPIGIQGRTPGAMAGMQYPQQQ--MPPQYGQQGV 531 Query: 802 LGALSLGS---FNKPSSKDNLFGQSCLAALSTACQNMIASLGAPNLNVTFNKKNPPEGKR 858 G G +++ +L Q+ L + Q + + PP Sbjct: 532 SGYCQQGQQPYYSQQPQPPHLPPQA--QYLPSQSQQRYQPQQDMSQEGYGTRSQPPLAPG 589 Query: 859 K-------LSQNETDGAAVAGNPGSDYFPGGTAPGAPGPGGPSGTSSSGSKASGPPNPPA 911 K L Q E + + D P GT SG++SS S P P Sbjct: 590 KPNHEDLNLIQQERPSSLPDLSGSIDDLPTGTEATLSSAVSASGSTSSQGDQSNPAQSP- 648 Query: 912 QGDGTSLSPNYTLESTSGNDGKPVSGGGGRGRGRRKRDSGHVSPGTFFDKYSAAPDSGGA 971 SP+ + S G P G G + SG +SP A+ Sbjct: 649 ------FSPHAS-PHLSSIPGGPSPSPVGSPVGSNQSRSGPISP--------ASIPGSQM 693 Query: 972 PGVSPGQQQASGAAVGGSSAGETRGAPTPHEKALTSPSWGKGAELLLGDQPDLIGSLDGG 1031 P PG Q S SS +P P E+ + + G Q G Sbjct: 694 PPQPPGSQSES------SSHPALSQSPMPQERGFMAGTQRNPQMAQYGPQQT------GP 741 Query: 1032 AKSDSSSPN------VGEFASDEVSTSYANEDEVSSSSDNPQALVKASRSPLVTGSPKLP 1085 + S SP + F S +Y + S PQ SR P +G P Sbjct: 742 SMSPHPSPGGQMHAGISSFQQSNSSGTYGPQ----MSQYGPQG--NYSRPPAYSGVPSAS 795 Query: 1086 PRGVGAGE----------HGPKAPPPALGLGIMSNSTSTPDSYGGGGGPGHPGTPGLEQV 1135 G G G GP P A+ LG M ++ + G P +PG+ Q Sbjct: 796 YSGPGPGMGISANNQMHGQGPSQPCGAVPLGRMPSAGMQNRPFPGNMSSMTPSSPGMSQQ 855 Query: 1136 RTPTSSSGAPPP 1147 P G P P Sbjct: 856 GGP--GMGPPMP 865 Score = 46.2 bits (108), Expect = 2e-04 Identities = 178/865 (20%), Positives = 269/865 (31%), Gaps = 202/865 (23%) Query: 94 GQQPHHGHPGSHHPHQHHPHFGGNFGGPDP-----GASCLHGGRLLG-----------YG 137 G PH P Q P+ GG++G P P G G + G YG Sbjct: 474 GSNPHS------QPQQSSPYPGGSYGPPGPQRYPIGIQGRTPGAMAGMQYPQQQMPPQYG 527 Query: 138 --GAAG----------GLGSQPPFAEGYEHMAESQGPESFGPQRPGNLPDFHSSGASSHA 185 G +G QPP SQ + + PQ+ D G + + Sbjct: 528 QQGVSGYCQQGQQPYYSQQPQPPHLPPQAQYLPSQSQQRYQPQQ-----DMSQEGYGTRS 582 Query: 186 VP--APCLPLDQSPNRAASFH--GLPSSSGSDSHSLEPRRVTNQGAVD-SLEYNYPGEAP 240 P AP P + N LP SGS T AV S + G+ Sbjct: 583 QPPLAPGKPNHEDLNLIQQERPSSLPDLSGSIDDLPTGTEATLSSAVSASGSTSSQGDQS 642 Query: 241 SGHFDMFSPSDSEGQLPHYAAGRQVPGGAFPGASAMPRAAGMVGLSKMHAQP--PQQQPQ 298 + FSP S PH ++ +PGG P P VG ++ + P P P Sbjct: 643 NPAQSPFSPHAS----PHLSS---IPGGPSPSPVGSP-----VGSNQSRSGPISPASIPG 690 Query: 299 QQQQPQQQQQQHGVFFERFSGARKMPVGLEPSVGSRHPLMQPPQQAPPPPQQQPPQQPPQ 358 Q PQ Q S + P + + M Q+ P Q P Q P Sbjct: 691 SQMPPQPPGSQ--------SESSSHPALSQSPMPQERGFMAGTQRNPQMAQYGPQQTGPS 742 Query: 359 QQPPPPP------GLLVRQNSCPPALPRPQQGE-------------AGTPSGGLQDGGPM 399 P P P G+ Q S PQ + +G PS GP Sbjct: 743 MSPHPSPGGQMHAGISSFQQSNSSGTYGPQMSQYGPQGNYSRPPAYSGVPSASYSGPGPG 802 Query: 400 L------------PSQHAQF----EYPIHRLENR-------SMHPYSEPVFSMQHP---P 433 + PSQ P ++NR SM P S + P P Sbjct: 803 MGISANNQMHGQGPSQPCGAVPLGRMPSAGMQNRPFPGNMSSMTPSSPGMSQQGGPGMGP 862 Query: 434 PQQAPNQRLQHFDAPPYM---NVAKRPRFDFPGSAGVDRCASWNGSMHNGALDNHLSPSA 490 P N++ Q A N A+ + FPG AS S ++ ++N S Sbjct: 863 PMPTVNRKAQEAAAAVMQAAANSAQSRQGSFPGMNQSGLMAS--SSPYSQPMNNSSSLMN 920 Query: 491 YPGLPGEFTPPVPDSFPSGPPLQHP-APDHQSLQQQQQQQQQQQQQQQQQQQQQQQQQQQ 549 P P + +S + L +P L + +++ Q + + ++ Sbjct: 921 TQAPPYSMAPAMVNSSAASVGLADMMSPGESKLPLPLKADGKEEGTPQPESKSKKSSSST 980 Query: 550 QRQNAALMIKQMASRNQQQRLRQPNLAQLGHPGD-------VGQGGL------VHGGPVG 596 + ++ + +++ L + G VG+ L V +G Sbjct: 981 TTGEKITKVYELGNEPERKLWVDRYLTFMEERGSPVSSLPAVGKKPLDLFRLYVCVKEIG 1040 Query: 597 GLAQPNFEREGGSTGAG-RLGTFEQQAPHLAQESAWF---------SGPHPPP------- 639 GLAQ N ++ +GT A L ++ + G PPP Sbjct: 1041 GLAQVNKNKKWRELATNLNVGTSSSAASSLKKQYIQYLFAFECKIERGEEPPPEVFSTGD 1100 Query: 640 -------------------GDLLPRRMGGSGL---PADCGPHDPSLAP----PPPPGG-- 671 G P+ G + + P D P P+ P P GG Sbjct: 1101 TKKQPKLQPPSPANSGSLQGPQTPQSTGSNSMAEVPGDLKPPTPASTPHGQMTPMQGGRS 1160 Query: 672 --------------------SGVLFRGPLQEPMRMPGE-GHVPALPSPGLQFGGSLGGLG 710 + + P Q+ M MP G +P P+ FGG G Sbjct: 1161 STISVHDPFSDVSDSSFPKRNSMTPNAPYQQGMSMPDVMGRMPYEPNKD-PFGGMRKVPG 1219 Query: 711 QLQSPGAGVGLPSAASE---RRPPPPDFATSALGGQPGFPFGAAGRQSTPHSGPGVNSPP 767 + +P+++ + + P + +G + FP+GA+ H G P Sbjct: 1220 SSEPFMTQGQMPNSSMQDMYNQSPSGAMSNLGMGQRQQFPYGAS--YDRRHEPYGQQYPG 1277 Query: 768 SAGGGGGSSGGGGGGGAYPPQPDFQ 792 G GG G YP QP+++ Sbjct: 1278 QGPPSGQPPYGGHQPGLYPQQPNYK 1302 Score = 41.6 bits (96), Expect = 0.005 Identities = 33/102 (32%), Positives = 40/102 (39%), Gaps = 14/102 (13%) Query: 294 QQQPQQQQQPQQQQQQHGVFFERFSGARKMPVGLEPSVGSRHPLMQPPQQAPPPPQQQPP 353 QQQ QQQQQ QQQQQQH + G G P P + P + Sbjct: 58 QQQQQQQQQQQQQQQQHPISNNNSLG----------GAGGGAPQPGPDMEQPQHGGAKDS 107 Query: 354 QQPPQQQPPPPPGLLVR---QNSCPPALPRPQQGEAGTPSGG 392 Q PP PP LL + ++ PP + P G P G Sbjct: 108 AAGGQADPPGPP-LLSKPGDEDDAPPKMGEPAGGRYEHPGLG 148 Score = 33.1 bits (74), Expect = 1.8 Identities = 81/347 (23%), Positives = 117/347 (33%), Gaps = 83/347 (23%) Query: 51 AMSALGEPPILGMNME-PYGFHARGHSELHAGGLQAQPVHGFFGGQQPHHGHPGSHHPHQ 109 AMS LG +G + PYG + H Q P G GQ P+ GH +P Q Sbjct: 1246 AMSNLG----MGQRQQFPYG---ASYDRRHEPYGQQYPGQGPPSGQPPYGGHQPGLYPQQ 1298 Query: 110 --HHPHFGGNFGGPDPGASCLHGGRLLG-------------YGGAAGGLGSQPPFAEGYE 154 + H G +G P + H G + YGG+ G +P Sbjct: 1299 PNYKRHMDGMYGPP----AKRHEGDMYNMQYSSQQQEMYNQYGGSYSGPDRRP------- 1347 Query: 155 HMAESQGPESFGPQR---PGNLPDFHSSGASSHAVPAPCLPLDQSPNRAASFHGLPSSSG 211 + Q P + +R PG + +H +P + P +++S G + Sbjct: 1348 --IQGQYPYPYSRERMQGPGQI--------QTHGIPPQMM---GGPLQSSSSEGPQQNMW 1394 Query: 212 SDSHSLEPRRVTNQGAVDSLEY-NYPGEAPSGHFDMFSPS---DSEGQLPHYAAGRQVPG 267 + + + QG + YPG + DM P + E Q P + + RQ Sbjct: 1395 AARNDMPYPYQNRQGPGGPTQAPPYPGMNRTD--DMMVPDQRINHESQWPSHVSQRQ--- 1449 Query: 268 GAFPGASAMPRAAGMVGLSKMHAQPPQQQPQQQQQPQQQQQQH-GVFFERFSGARKMPVG 326 M +A M QP + PQ Q H S R + Sbjct: 1450 ------PYMSSSASM--------QPITRPPQPSYQTPPSLPNHISRAPSPASFQRSLENR 1495 Query: 327 LEPSVGSRHPLMQPPQQAPPPPQQQPPQQPPQQQPPP-------PPG 366 + PS P M+ + P P Q PP QPPP PPG Sbjct: 1496 MSPSKSPFLPSMKMQKVMPTVPTSQVTGPPP--QPPPIRREITFPPG 1540 >gi|89276751 alpha 1 type V collagen preproprotein [Homo sapiens] Length = 1838 Score = 94.4 bits (233), Expect = 7e-19 Identities = 255/1021 (24%), Positives = 320/1021 (31%), Gaps = 209/1021 (20%) Query: 43 GPPGPVDPAMSALGEPPILGMNMEPYGFHARGHSELHAGGLQAQPVHGFFGGQQPHHGHP 102 GPPGP P P + GM+ +P +G+ G Q +P G G+P Sbjct: 688 GPPGPPGP-------PGVTGMDGQP---GPKGNV-----GPQGEP------GPPGQQGNP 726 Query: 103 GSHHPHQHHPHFGGNFGGPDPGASCLHGGRLLGYGGAAGGLGSQPPFAEGYEHMAESQGP 162 G+ Q P G G P G L G GA G G P EG QGP Sbjct: 727 GA----QGLPGPQGAIGPPGEKGPLGKPG-LPGMPGADGPPGH--PGKEGPPGEKGGQGP 779 Query: 163 ESFGPQRPGNLPDFHSSGASSHAVPAPCLPLDQSPNRAASFHGLPSSSGSDSHSLEPRRV 222 GPQ P P + A GL + G P Sbjct: 780 P--GPQGPIGYPG------------------PRGVKGADGIRGLKGTKGEKGEDGFPGFK 819 Query: 223 TNQGAV-DSLEYNYPGE-------------APSGHFDMFSPSDSEGQL-----PHYAAGR 263 + G D E PG P+G P +G+L P Y GR Sbjct: 820 GDMGIKGDRGEIGPPGPRGEDGPEGPKGRGGPNGDPGPLGPPGEKGKLGVPGLPGYP-GR 878 Query: 264 QVPGGA-----FPGASAMPRAAGMVGLSKMHAQPPQQQPQQQQQPQQQQQQHGVFFERFS 318 Q P G+ FPGA+ G G Q P+ ++ P+ + G Sbjct: 879 QGPKGSIGFPGFPGANGEKGGRGTPGKPGPRGQRGPTGPRGERGPRGITGKPGPKGNSGG 938 Query: 319 GARKMPVGLEPSVGSRHPLMQPPQQAPPPPQQQP--PQQPPQQQ---------PPPPPGL 367 P G G + P P + PP P + P P Q+ PP PPG+ Sbjct: 939 DGPAGPPGERGPNGPQGPTGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPPGV 998 Query: 368 LVRQNSCPPALPRPQQGEAGTPSGGLQDGGPMLPSQHAQFEYPIHRLENRSMHPYSEPVF 427 + Q P ++G G P + G P L + Sbjct: 999 VGPQGPTGETGPMGERGHPGPPGPPGEQGLPGLAGKEG---------------------- 1036 Query: 428 SMQHPPPQQAPNQRLQHFDAPPYMNVAKRPRFDFPGSAGVDRCASWNGSMHNGALDNHLS 487 + P P P + D PP + FPG G+ G N Sbjct: 1037 TKGDPGPAGLPGK-----DGPPGLR-------GFPGDRGLPGPVGALGLKGNEGPPGPPG 1084 Query: 488 PSAYPGLPGEFTPPVPDSFPSGP-PLQHPAPDHQSLQQQQQQQQQQQQQQQQQQQQQQQQ 546 P+ PG G P P P P P P ++ ++ Q + Q Sbjct: 1085 PAGSPGERGPAGAAGPIGIPGRPGPQGPPGP-------AGEKGAPGEKGPQGPAGRDGLQ 1137 Query: 547 QQQQRQNAALMIKQMASRNQQQRLRQPNLAQLGHPGDVG-QGGLVHGGPVGGLAQPNFER 605 A + + + +P Q G GD G QG GP G + QP Sbjct: 1138 GPVGLPGPAGPVGPPGEDGDKGEIGEP--GQKGSKGDKGEQGPPGPTGPQGPIGQPGPSG 1195 Query: 606 EGGSTG-AGRLGTFEQQAPHLAQESAWFSGPHPPPG-DLLP---------RRMGGSGLPA 654 G G G+ G F Q+ + F GP P G LP +G G P Sbjct: 1196 ADGEPGPRGQQGLFGQKGD---EGPRGFPGPPGPVGLQGLPGPPGEKGETGDVGQMGPPG 1252 Query: 655 DCGPHDPSLA-----PPPPPGGSGVLFRGPLQEPMRMPGEGHVPALPSPGLQFG--GSLG 707 GP PS A P PPGG G G + E PGE P LP G G G G Sbjct: 1253 PPGPRGPSGAPGADGPQGPPGGIG--NPGAVGEKGE-PGEAGEPGLPGEGGPPGPKGERG 1309 Query: 708 GLGQLQSPGAGVGLPSAASERRPPPPDFATSALGGQPGFPFGAAGRQSTPHSGP-GVNSP 766 G+ P G P + PP D G GFP G G P GP G + P Sbjct: 1310 EKGE-SGPSGAAGPPGP----KGPPGDDGPKGSPGPVGFP-GDPGPPGEP--GPAGQDGP 1361 Query: 767 PSAGGGGGSSG-GGGGGGAYPPQPDFQPSQRTSASKLGALSLGSFNKPSSKDNLFGQSCL 825 P G G G G G P P P +R G P + G Sbjct: 1362 PGDKGDDGEPGQTGSPGPTGEPGPSGPPGKRGPPGPAG---------PEGRQGEKGAKGE 1412 Query: 826 AALS--TACQNMIASLGAPNLNVTFNKKNPPEGKRKLSQNETDGAAVAGNPGSDYFPGGT 883 A L I GAP K P+G R + G G PG Sbjct: 1413 AGLEGPPGKTGPIGPQGAPG-------KPGPDGLR----------GIPGPVGEQGLPGSP 1455 Query: 884 AP-GAPGPGGPSGTSSSGSKA-SGPPNPPAQGDGTSLSPNYTLESTSGNDGKPVSGG--G 939 P G PGP GP G G K SGP L + G+ G P G G Sbjct: 1456 GPDGPPGPMGPPGL--PGLKGDSGPKGEKGHPGLIGLIGPPGEQGEKGDRGLPGPQGSSG 1513 Query: 940 GRGRGRRKRDSGHVSPGTFFDKYSAAPDSGGAPGVSPGQQQASGAAVGGSSAGETRGAPT 999 +G SG + P P G PG PG + A G++ GE G P Sbjct: 1514 PKGEQGITGPSGPIGP----------PGPPGLPG-PPGPKGAKGSSGPTGPKGEA-GHPG 1561 Query: 1000 P 1000 P Sbjct: 1562 P 1562 Score = 82.8 bits (203), Expect = 2e-15 Identities = 168/624 (26%), Positives = 214/624 (34%), Gaps = 84/624 (13%) Query: 579 GHPGDVGQGGLVHG-GPVGGLAQPNFEREGGSTGA-GRLGTFEQQAPHLAQESAWFSG-P 635 G PG+ G GL+ GP G P G G G +G + P Q + G P Sbjct: 673 GLPGEPGPRGLLGPKGPPGPPGPPGVTGMDGQPGPKGNVGPQGEPGPPGQQGNPGAQGLP 732 Query: 636 HP-----PPGDLLPR-RMGGSGLPADCGP--HDPSLAPPPPPGGSGVLFRGPLQEPMRMP 687 P PPG+ P + G G+P GP H PP GG G GP Q P+ P Sbjct: 733 GPQGAIGPPGEKGPLGKPGLPGMPGADGPPGHPGKEGPPGEKGGQGP--PGP-QGPIGYP 789 Query: 688 GEGHVPALPS-PGLQFGGSLGGLGQLQSPG--AGVGLPSAASERRPPPPDFATSALG--- 741 G V GL+ G+ G G+ PG +G+ E PP P G Sbjct: 790 GPRGVKGADGIRGLK--GTKGEKGEDGFPGFKGDMGIKGDRGEIGPPGPRGEDGPEGPKG 847 Query: 742 -----GQPG--FPFGAAGRQSTPH--SGPGVNSPPSAGGGGGSSGGGG--GGGAYPPQPD 790 G PG P G G+ P PG P + G G G G GG P +P Sbjct: 848 RGGPNGDPGPLGPPGEKGKLGVPGLPGYPGRQGPKGSIGFPGFPGANGEKGGRGTPGKPG 907 Query: 791 FQPSQRTSASKLGALSLGSFNKPSSKDNLFGQSCLAALSTACQNMIASLGAPNLNVTF-N 849 + + + + G KP K N G N P F Sbjct: 908 PRGQRGPTGPRGERGPRGITGKPGPKGNSGGDGPAGPPGERGPN------GPQGPTGFPG 961 Query: 850 KKNPPEGKRKLSQNETDGA-AVAGNPGSDYFPGGTAPGAP----GPGGPSG-TSSSGSKA 903 K PP K DG G G F G T P P GP GP+G T G + Sbjct: 962 PKGPPGPPGK------DGLPGHPGQRGETGFQGKTGPPGPPGVVGPQGPTGETGPMGERG 1015 Query: 904 S-GPPNPPAQGDGTSLSPNYTLESTSGNDGKPVSGGGGRGRGRRKRDSGHVSP-GTFFDK 961 GPP PP + L+ + G G P G RG D G P G K Sbjct: 1016 HPGPPGPPGEQGLPGLAGKEGTKGDPGPAGLPGKDGPPGLRGF-PGDRGLPGPVGALGLK 1074 Query: 962 YSAAPDSGGAPGVSPGQQQASGAA--VGGSSAGETRGAP-------TPHEKALTSPSWGK 1012 + P P SPG++ +GAA +G +G P P EK P+ Sbjct: 1075 GNEGPPGPPGPAGSPGERGPAGAAGPIGIPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRD 1134 Query: 1013 GAELLLGDQPDLIGSLDGGAKSDSSSPNVGEFASDEVSTSYANEDEVSSSSDNPQALVKA 1072 G + +G P G + G D +GE + + ++ PQ + Sbjct: 1135 GLQGPVG-LPGPAGPV-GPPGEDGDKGEIGE--PGQKGSKGDKGEQGPPGPTGPQGPIGQ 1190 Query: 1073 SRSPLVTGSPKLPPRGVGA-----GEHGPK---APPPALGLGIMSNSTSTPDSYGGGGGP 1124 G P PRG G+ GP+ PP +GL + G G Sbjct: 1191 PGPSGADGEPG--PRGQQGLFGQKGDEGPRGFPGPPGPVGLQGLPGPPGEKGETGDVGQM 1248 Query: 1125 GHPGTPGLEQVRTPTSSSGAPPPD 1148 G PG PG P SGAP D Sbjct: 1249 GPPGPPG------PRGPSGAPGAD 1266 Score = 82.8 bits (203), Expect = 2e-15 Identities = 177/631 (28%), Positives = 206/631 (32%), Gaps = 132/631 (20%) Query: 579 GHPGDVG-QGGLVHGGPVGGLAQPNFEREGGSTG----AGRLGTFEQQAPHLAQESAWFS 633 G PG VG QG GP+G P G G AG+ GT P Sbjct: 994 GPPGVVGPQGPTGETGPMGERGHPGPPGPPGEQGLPGLAGKEGTKGDPGPAGLPGKDGPP 1053 Query: 634 GPHPPPGDL-LPRRMGGSGLPADCGPHDPSLAPPPPPGGSGVLFRGPLQE--PMRMPGEG 690 G PGD LP +G GL + GP PP P G G RGP P+ +PG Sbjct: 1054 GLRGFPGDRGLPGPVGALGLKGNEGPP----GPPGPAGSPGE--RGPAGAAGPIGIPGRP 1107 Query: 691 HVPALPSPGLQFG-----GSLGGLGQ--LQSPGAGVGLPSAASERRPPPPDFATSALG-- 741 P P + G G G G+ LQ P VGLP A PP D +G Sbjct: 1108 GPQGPPGPAGEKGAPGEKGPQGPAGRDGLQGP---VGLPGPAGPVGPPGEDGDKGEIGEP 1164 Query: 742 GQPGFPFGAAGRQSTPH-SGP-GVNSPPSAGGGGGSSGGGGGGGAYPPQPDFQPSQRTSA 799 GQ G G G Q P +GP G P G G G G G + + D P R Sbjct: 1165 GQKGSK-GDKGEQGPPGPTGPQGPIGQPGPSGADGEPGPRGQQGLFGQKGDEGP--RGFP 1221 Query: 800 SKLGALSLGSFNKPSSKDNLFGQSCLAALSTACQNMIASLGAPNLNVTFNKKNPPEGKRK 859 G + L P + G + +G P PP + Sbjct: 1222 GPPGPVGLQGLPGPPGEKGETGD-------------VGQMGPPG---------PPGPRGP 1259 Query: 860 LSQNETDGAAVAGNPGSDYFPGGTA----------PGAPGPGGPSGTS--------SSGS 901 DG G PG PG PG PG GGP G S S Sbjct: 1260 SGAPGADGPQ--GPPGGIGNPGAVGEKGEPGEAGEPGLPGEGGPPGPKGERGEKGESGPS 1317 Query: 902 KASGPPNP--PAQGDGTSLSPNYTLESTSGNDGKPVSGG--GGRGRGRRKRDSGHV---- 953 A+GPP P P DG SP G+ G P G G G K D G Sbjct: 1318 GAAGPPGPKGPPGDDGPKGSPGPV--GFPGDPGPPGEPGPAGQDGPPGDKGDDGEPGQTG 1375 Query: 954 SPG-TFFDKYSAAPDSGGAPGVS-----PGQQQASGAAVGGSSAGET------------- 994 SPG T S P G PG + G++ A G A G+T Sbjct: 1376 SPGPTGEPGPSGPPGKRGPPGPAGPEGRQGEKGAKGEAGLEGPPGKTGPIGPQGAPGKPG 1435 Query: 995 ----RGAPTP-HEKALTSPSWGKGAELLLGDQ--PDLIGSLDGGAKSDSSSPNV------ 1041 RG P P E+ L G +G P L G D G K + P + Sbjct: 1436 PDGLRGIPGPVGEQGLPGSPGPDGPPGPMGPPGLPGLKG--DSGPKGEKGHPGLIGLIGP 1493 Query: 1042 -GEFASDEVSTSYANEDEVSSSSDNPQALVKASRSPLVTGSPKLPPRGVGAGEHGPKAPP 1100 GE E + SS Q + S G P LP GP P Sbjct: 1494 PGE--QGEKGDRGLPGPQGSSGPKGEQGITGPSGPIGPPGPPGLP---------GPPGPK 1542 Query: 1101 PALGLGIMSNSTSTPDSYGGGGGPGHPGTPG 1131 A G S T G G PG PG PG Sbjct: 1543 GAKG---SSGPTGPKGEAGHPGPPGPPGPPG 1570 Score = 82.4 bits (202), Expect = 3e-15 Identities = 163/607 (26%), Positives = 200/607 (32%), Gaps = 98/607 (16%) Query: 579 GHPGDVGQGGLV----HGGPVGGLAQPNFEREGGSTGAGRLGTFEQQAPHLAQESAWFSG 634 G PG GQ G GP G +P +G S G G G ++ P+ Q F G Sbjct: 904 GKPGPRGQRGPTGPRGERGPRGITGKPG--PKGNSGGDGPAGPPGERGPNGPQGPTGFPG 961 Query: 635 PHPPPGDLLPRRMGGSGLPADCGP--HDPSLAPPPPPGGSGVLFRGPLQEPMRMPGEGHV 692 P PPG P + G G P G PP PPG G +GP E M GH Sbjct: 962 PKGPPGP--PGKDGLPGHPGQRGETGFQGKTGPPGPPGVVGP--QGPTGETGPMGERGH- 1016 Query: 693 PALPSPGLQFG--GSLGGLGQLQSPGAGVGLPSAASERRPPPPDFATSALGGQPGFPFGA 750 P P P + G G G G PG GLP + PP G PG P GA Sbjct: 1017 PGPPGPPGEQGLPGLAGKEGTKGDPGPA-GLPG----KDGPPGLRGFPGDRGLPG-PVGA 1070 Query: 751 AGRQST--PHSGPGVNSPPSAGGGGGSSGGGGGGGAYPPQPDFQPSQRTSASKLGALSLG 808 G + P PG P G G++G G G PQ P A + GA Sbjct: 1071 LGLKGNEGPPGPPGPAGSPGERGPAGAAGPIGIPGRPGPQGPPGP-----AGEKGAPGEK 1125 Query: 809 SFNKPSSKDNLFGQSCLAALSTAC--------QNMIASLGAPNLNVTFNKKNPPEG---K 857 P+ +D L G L + + I G ++ PP + Sbjct: 1126 GPQGPAGRDGLQGPVGLPGPAGPVGPPGEDGDKGEIGEPGQKGSKGDKGEQGPPGPTGPQ 1185 Query: 858 RKLSQNETDGA-------------AVAGNPGSDYFPGGTAP----GAPGPGGPSGTSSSG 900 + Q GA G+ G FPG P G PGP G G + Sbjct: 1186 GPIGQPGPSGADGEPGPRGQQGLFGQKGDEGPRGFPGPPGPVGLQGLPGPPGEKGETGDV 1245 Query: 901 SKASGPPNPPAQGDGTSLSPNYTLESTSGNDGKPVSGGGGRGRGRRKRDSGHVS-PGTFF 959 + GPP PP G S +P G G P G G G K + G PG Sbjct: 1246 GQM-GPPGPPGPR-GPSGAPG-----ADGPQGPP-GGIGNPGAVGEKGEPGEAGEPGL-- 1295 Query: 960 DKYSAAPDSGGAPGVSPGQQQASGAAVGGSSAGETRGAPTPHEKALTSPSWGKGAELLLG 1019 P GG PG G++ G + +AG P + P G G Sbjct: 1296 ------PGEGGPPGPK-GERGEKGESGPSGAAGPPGPKGPPGDDG---PKGSPGPVGFPG 1345 Query: 1020 DQPDLIGSLDGGAKSDSSSPNVGEFASDEVSTSYANEDEVSSSSDNPQALVKASRSPLVT 1079 D P G G A D + G+ + S E S R P Sbjct: 1346 D-PGPPGE-PGPAGQDGPPGDKGDDGEPGQTGSPGPTGEPGPSGP------PGKRGPPGP 1397 Query: 1080 GSPKLPPRGVGA-GEHGPKAPPPALGLGIMSNSTSTPDSYGGGGGPGHPGTPGLEQVRTP 1138 P+ GA GE G + PP G G G PG PG GL + P Sbjct: 1398 AGPEGRQGEKGAKGEAGLEGPPGKTG------------PIGPQGAPGKPGPDGLRGIPGP 1445 Query: 1139 TSSSGAP 1145 G P Sbjct: 1446 VGEQGLP 1452 Score = 82.0 bits (201), Expect = 3e-15 Identities = 179/705 (25%), Positives = 230/705 (32%), Gaps = 113/705 (16%) Query: 486 LSPSAYPGLPGEFTPPVPDSFPSGPPLQHPAPDHQSLQQQQQQQQQQQQQQQQQQQQQQQ 545 + P+ G PGE PP P L P P + + + Q+ Sbjct: 486 MGPTGQVGDPGERGPPGRPGLPGADGLPGP-PGTMLMLPFRFGGGGDAGSKGPMVSAQES 544 Query: 546 QQQQQRQNAALMIK----QMASRNQQQRLRQPNLAQL-GHPGDVG-QGGLVHGGPVGGLA 599 Q Q Q A L ++ M + + P L G PGDVG QG GP G Sbjct: 545 QAQAILQQARLALRGPAGPMGLTGRPGPVGPPGSGGLKGEPGDVGPQGPRGVQGPPGPAG 604 Query: 600 QPNFEREGGSTGA----GRLGT-----FEQQAPHLAQE----SAWFSGPHPPPGDLLPR- 645 +P GS GA G+ G F+ A ++ SGP PPGD R Sbjct: 605 KPGRRGRAGSDGARGMPGQTGPKGDRGFDGLAGLPGEKGHRGDPGPSGPPGPPGDDGERG 664 Query: 646 ---RMGGSGLPADCGPHDPSLAPPPPPGGSGVLFRGPLQEPMRMPGEGHVPALPSPGLQF 702 +G GLP + GP L P PPG P PG + P P Sbjct: 665 DDGEVGPRGLPGEPGPRG-LLGPKGPPG------------PPGPPGVTGMDGQPGPKGNV 711 Query: 703 G--GSLGGLGQLQSPGAGVGLPSAASERRPPPPDFATSALGGQPGFPFGAAGRQSTPHSG 760 G G G GQ +PGA GLP PP G+PG P Sbjct: 712 GPQGEPGPPGQQGNPGA-QGLPGPQGAIGPP----GEKGPLGKPGLP-----------GM 755 Query: 761 PGVNSPPSAGGGGGSSGGGGGGGAYPPQ-PDFQPSQRTSASKLGALSLGSFNKPSSKDNL 819 PG + PP G G G GG G PQ P P R G L +D Sbjct: 756 PGADGPPGHPGKEGPPGEKGGQGPPGPQGPIGYPGPRGVKGADGIRGLKGTKGEKGEDGF 815 Query: 820 FGQSCLAALSTACQNMIASLGAPNLNVTFNKKNPPEGKRKLSQNETDGAAVA--GNPGSD 877 G + +G P ++ PEG + D + G G Sbjct: 816 PGFKG----DMGIKGDRGEIGPPGP----RGEDGPEGPKGRGGPNGDPGPLGPPGEKGKL 867 Query: 878 YFPGGTAPGAPGPGGPSGTSSSGSKASGPPNPPAQGDGTSLSPNYTLESTSGNDGKPVSG 937 PG PG PG GP G+ P P A G+ + G GKP Sbjct: 868 GVPG--LPGYPGRQGPKGS------IGFPGFPGANGE----------KGGRGTPGKP--- 906 Query: 938 GGGRGRGRRKRDSGHVSPGTFFDKYSAAPDSGG-APGVSPGQQQASGAAVGGSSAGETRG 996 G RG+ G P K +SGG P PG++ +G G + +G Sbjct: 907 -GPRGQRGPTGPRGERGPRGITGKPGPKGNSGGDGPAGPPGERGPNGPQ-GPTGFPGPKG 964 Query: 997 APTPHEK-ALTSPSWGKGAELLLG-----DQPDLIG----SLDGGAKSDSSSPNVGEFAS 1046 P P K L +G G P ++G + + G + P Sbjct: 965 PPGPPGKDGLPGHPGQRGETGFQGKTGPPGPPGVVGPQGPTGETGPMGERGHPGPPGPPG 1024 Query: 1047 DEVSTSYANEDEVSSSSDNPQALVKASRSPLVTGSP--KLPPRGVGA----GEHGPKAPP 1100 ++ A + E + P L P + G P + P VGA G GP PP Sbjct: 1025 EQGLPGLAGK-EGTKGDPGPAGLPGKDGPPGLRGFPGDRGLPGPVGALGLKGNEGPPGPP 1083 Query: 1101 PALGLGIMSNSTSTPDSYGGGGGPGHPGTPGLEQVRTPTSSSGAP 1145 G S G G G PG PG + P GAP Sbjct: 1084 GPAG------SPGERGPAGAAGPIGIPGRPGPQGPPGPAGEKGAP 1122 Score = 73.2 bits (178), Expect = 2e-12 Identities = 161/610 (26%), Positives = 194/610 (31%), Gaps = 130/610 (21%) Query: 579 GHPGDVGQGGLVHGGPVGGLAQPNFEREGGSTGAGRLGTF----EQQAPHLAQESAW-FS 633 G PG G GL GP G + F R GG AG G E QA + Q++ Sbjct: 502 GRPGLPGADGLP--GPPGTMLMLPF-RFGGGGDAGSKGPMVSAQESQAQAILQQARLALR 558 Query: 634 GPHPP------PGDLLPRRMGG-SGLPADCGPHDPS--LAPPPPPGGSGVLFRGPLQEPM 684 GP P PG + P GG G P D GP P PP P G G R Sbjct: 559 GPAGPMGLTGRPGPVGPPGSGGLKGEPGDVGPQGPRGVQGPPGPAGKPGRRGRAGSDGAR 618 Query: 685 RMPGEGHVPALPSPGLQFGGSLGGL----GQLQSPG-AGVGLPSAASERRPPPPDFATSA 739 MPG+ P F G L GL G PG +G P R + Sbjct: 619 GMPGQTG----PKGDRGFDG-LAGLPGEKGHRGDPGPSGPPGPPGDDGERGDDGEVGPRG 673 Query: 740 LGGQPGFPFGAAGRQSTPHSGPGVNSPPSAGGGGGSSGGGGGGGAY----PPQPDFQPSQ 795 L G+PG P G G P PG PP G G G G G PP P Sbjct: 674 LPGEPG-PRGLLG----PKGPPGPPGPPGVTGMDGQPGPKGNVGPQGEPGPPGQQGNPGA 728 Query: 796 RTSASKLGALSLGSFNKPSSKDNLFGQSCLAALSTACQNMIASLGAPNLNVTFNKKNPPE 855 + GA+ P K L G M + G P K+ PP Sbjct: 729 QGLPGPQGAIGPPGEKGPLGKPGLPG-------------MPGADGPPGHP---GKEGPP- 771 Query: 856 GKRKLSQNETDGAAVAGNPGSDYFPGGTA-PGAPGPGGPSGTSSSGSKASGPP---NPPA 911 E G G G +PG GA G G GT + P + Sbjct: 772 -------GEKGGQGPPGPQGPIGYPGPRGVKGADGIRGLKGTKGEKGEDGFPGFKGDMGI 824 Query: 912 QGDGTSLSPNYTLESTSGNDGKPVSGGGGRGRGRRKRDSGHVSPGTFFDKYSAAPDSGGA 971 +GD + P G DG G +GRG D G + P K G Sbjct: 825 KGDRGEIGP----PGPRGEDGPE----GPKGRGGPNGDPGPLGPPGEKGKLGVP----GL 872 Query: 972 PGVSPGQQQASGA--------AVGGSSAGETRGAPTPH-EKALTSPSWGKGAELLLGDQP 1022 PG PG+Q G+ A G T G P P ++ T P +G + G Sbjct: 873 PGY-PGRQGPKGSIGFPGFPGANGEKGGRGTPGKPGPRGQRGPTGPRGERGPRGITGKP- 930 Query: 1023 DLIGSLDGGAKSDSSSPNVGEFASDEVSTSYANEDEVSSSSDNPQALVKASRSPLVTGSP 1082 G K +S D P A R P P Sbjct: 931 --------GPKGNSGG-------------------------DGP-AGPPGERGP---NGP 953 Query: 1083 KLPPRGVGAGEHGPKAPPPALGLGIMSNSTSTPDSYGGGGGPGHPGTPGLEQVRTPTSSS 1142 + P G GPK PP G + G G G PG PG+ + PT + Sbjct: 954 QGP-----TGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPPGVVGPQGPTGET 1008 Query: 1143 GAPPPDEIHP 1152 G P + HP Sbjct: 1009 G-PMGERGHP 1017 Score = 68.2 bits (165), Expect = 5e-11 Identities = 148/598 (24%), Positives = 189/598 (31%), Gaps = 113/598 (18%) Query: 564 RNQQQRLRQPNLAQLGHPGDVGQGGLVHGGPVGGLAQPNFEREGGSTGA-GRLGTFEQQA 622 RN + P P ++G G + + +E GG G G+ G Sbjct: 410 RNLDENYYDPYYDPTSSPSEIGPGMPANQDTI-------YEGIGGPRGEKGQKGE----- 457 Query: 623 PHLAQESAWFSGPHPPPGDLLPRRMGGSGLPADCGPHDPSLAPPPPPGGSGVLFRGPLQE 682 P + + GP P G +GLP G ++ P G G RGP Sbjct: 458 PAIIEPGMLIEGPPGPEGP--------AGLPGPPG----TMGPTGQVGDPGE--RGPPGR 503 Query: 683 PMRMPGEGHVPALPSPGLQFGGSLGGLGQLQSPGAGVGLPSAASERRPPPPDFATSALGG 742 P +PG +P P L GG G S G V SA + A AL G Sbjct: 504 P-GLPGADGLPGPPGTMLMLPFRFGGGGDAGSKGPMV---SAQESQAQAILQQARLALRG 559 Query: 743 QPGFPFGAAGRQSTPHSGPGVNSPPSAGGGGGSSGGGGGGGAY----PPQPDFQPSQRTS 798 G P G GR PG PP +GG G G G G PP P +P +R Sbjct: 560 PAG-PMGLTGR-------PGPVGPPGSGGLKGEPGDVGPQGPRGVQGPPGPAGKPGRRGR 611 Query: 799 ASKLGALSLGSFNKPSSKDNLFGQSCLAALSTACQNMIASLGAPNLNVTFNKKNPP--EG 856 A GA + P G + L G P + PP +G Sbjct: 612 AGSDGARGMPGQTGPKGDRGFDGLAGLPGEK-------GHRGDPGPS---GPPGPPGDDG 661 Query: 857 KRKLSQNETDGAAVAGNPGSDYFPGGTA-PGAPGPGGPSGTSSS-GSKAS----GPPNPP 910 +R E + G PG G PG PGP G +G G K + G P PP Sbjct: 662 ERG-DDGEVGPRGLPGEPGPRGLLGPKGPPGPPGPPGVTGMDGQPGPKGNVGPQGEPGPP 720 Query: 911 AQGDGTSLSPNYTLESTSGNDGKPVSGGGGRGRGRRKRDSGHVSPGTFFDKYSAAPDSGG 970 Q + G G P G G K G PG P + G Sbjct: 721 GQ------------QGNPGAQGLP-GPQGAIGPPGEKGPLG--KPG-----LPGMPGADG 760 Query: 971 APGVSPGQQQASGAAVGGSSAGETRGAPTPHEK-ALTSPSWGKGAELLLGDQPDLIGSLD 1029 PG PG++ G G +G P P P KGA+ + G + Sbjct: 761 PPG-HPGKEGPPGEKGG-------QGPPGPQGPIGYPGPRGVKGADGIRGLK-------- 804 Query: 1030 GGAKSDSSSPNVGEFASDEVSTSYANEDEVSSSSDNPQALVKASRSPLVTGSPKLPPRGV 1089 G K + F D + D + R PK RG Sbjct: 805 -GTKGEKGEDGFPGFKGD-----------MGIKGDRGEIGPPGPRGEDGPEGPK--GRGG 850 Query: 1090 GAGEHGPKAPPPALGLGIMSNSTSTPDSYGGGGGPGHPGTPGLEQVRTPTSSSGAPPP 1147 G+ GP PP G + P G G G PG PG + + G P P Sbjct: 851 PNGDPGPLGPPGEKGKLGVPGLPGYPGRQGPKGSIGFPGFPGANGEKGGRGTPGKPGP 908 Score = 53.5 bits (127), Expect = 1e-06 Identities = 74/243 (30%), Positives = 89/243 (36%), Gaps = 37/243 (15%) Query: 578 LGHPGDVGQGGLVHGGPVGGLAQPNFEREGGSTG-AGRLGTFEQQAPHLAQESAWFSGPH 636 +G PGD G G GP G P + + G G G G + P GP Sbjct: 1341 VGFPGDPGPPG--EPGPAGQDGPPGDKGDDGEPGQTGSPGPTGEPGPSGPPGKRGPPGPA 1398 Query: 637 PPPGDLLPRRMGGS----GLPADCGPHDPSLAP--PPPPGGSGVLFRGPLQE-------- 682 P G + G G P GP P AP P P G G+ GP+ E Sbjct: 1399 GPEGRQGEKGAKGEAGLEGPPGKTGPIGPQGAPGKPGPDGLRGI--PGPVGEQGLPGSPG 1456 Query: 683 PMRMPGEGHVPALPSPGLQFGGSLGGLGQLQSPG--AGVGLPSAASER--RPPPPDFATS 738 P PG P LP GL+ G G G+ PG +G P E+ R P +S Sbjct: 1457 PDGPPGPMGPPGLP--GLK--GDSGPKGEKGHPGLIGLIGPPGEQGEKGDRGLPGPQGSS 1512 Query: 739 ALGGQPGF--PFGAAGRQSTPHSGPGVNSPPSAGGGGGSSG----GGGGGGAYPPQPDFQ 792 G+ G P G G P PG+ PP G GSSG G G PP P Sbjct: 1513 GPKGEQGITGPSGPIG----PPGPPGLPGPPGPKGAKGSSGPTGPKGEAGHPGPPGPPGP 1568 Query: 793 PSQ 795 P + Sbjct: 1569 PGE 1571 Score = 50.8 bits (120), Expect = 8e-06 Identities = 178/722 (24%), Positives = 226/722 (31%), Gaps = 120/722 (16%) Query: 9 PQVNSRNAGQ----GERNFNETGLSMNTHFKAPAFHTGGPPGPVDPAMSALGEPPILGMN 64 P+ NS G GER N G T F P GPPGP P L P G Sbjct: 932 PKGNSGGDGPAGPPGERGPN--GPQGPTGFPGPK----GPPGP--PGKDGLPGHP--GQR 981 Query: 65 MEPYGFHARGHSELHAGGLQAQPVHGFFGGQQPHHGHPGSHHP--HQHHPHFGGNFGGP- 121 E GF + G + Q G G GHPG P Q P G G Sbjct: 982 GET-GFQGKTGPPGPPGVVGPQGPTGETG-PMGERGHPGPPGPPGEQGLPGLAGKEGTKG 1039 Query: 122 DPGASCLHGGRLLGYGGAAGGLGSQP-PFAEGYEHMAESQGPESFGPQRPGNLPDFHSSG 180 DPG + L G G G G G + P G + ++GP GP P P Sbjct: 1040 DPGPAGLPGKD--GPPGLRGFPGDRGLPGPVGALGLKGNEGPP--GPPGPAGSPGERGPA 1095 Query: 181 ASSHAVPAPCLPLDQSPNRAASFHGLPSSSGSDSHSLEPRRVTNQGAVDSLEYNYPGEA- 239 ++ + P P Q P A G P G + R QG V PG A Sbjct: 1096 GAAGPIGIPGRPGPQGPPGPAGEKGAPGEKGPQGPA---GRDGLQGPV-----GLPGPAG 1147 Query: 240 PSGHFDMFSPSDSEGQLPHYAAGRQVPGGAFPGASAMPRAAGMVGLSKMHAQPPQQQPQQ 299 P G P +G Q G P G G QP Sbjct: 1148 PVG------PPGEDGDKGEIGEPGQKGSKGDKGEQGPP---GPTGPQGPIGQPGPSGADG 1198 Query: 300 QQQPQQQQQQHGVFFER-FSGARKMP--------VGLEPSVGSRHPLMQPPQQAP--PPP 348 + P+ QQ G+F ++ G R P GL G + Q P PP Sbjct: 1199 EPGPRGQQ---GLFGQKGDEGPRGFPGPPGPVGLQGLPGPPGEKGETGDVGQMGPPGPPG 1255 Query: 349 QQQPPQQPPQQQPPPPPGLLVRQNSCPPALPRPQQGEAGTPSGGLQDGGPMLPSQHAQFE 408 + P P P PPG + + + + GEAG P G +GGP P Sbjct: 1256 PRGPSGAPGADGPQGPPGGIGNPGAVG---EKGEPGEAGEP-GLPGEGGPPGPK------ 1305 Query: 409 YPIHRLENRSMHPYSEPVFSMQHPPPQQAPNQRLQHFDAPPYMNVAKRPRFDFPGSAGVD 468 R S P + P P+ P D P FPG G Sbjct: 1306 ------GERGEKGESGPSGAAGPPGPKGPPGD-----DGPK----GSPGPVGFPGDPGPP 1350 Query: 469 RCASWNGSMHNGALDNHLSPSAYPGLPGEFTPPVP--DSFPSGPPLQHPAPDHQSLQQQQ 526 G D G PG+ P P + PSGPP + P Sbjct: 1351 ------GEPGPAGQDGPPGDKGDDGEPGQTGSPGPTGEPGPSGPPGKRGPPGPAG----- 1399 Query: 527 QQQQQQQQQQQQQQQQQQQQQQQQRQNAALMIKQMASRNQQQRLRQPNLAQLGHPGDVGQ 586 + +Q ++ + + + + + + + LR G PG VG+ Sbjct: 1400 ----PEGRQGEKGAKGEAGLEGPPGKTGPIGPQGAPGKPGPDGLR-------GIPGPVGE 1448 Query: 587 GGLVHG-------GPVGGLAQPNFEREGGSTG-AGRLGTFEQQAPHLAQESAWFSGPHPP 638 GL GP+G P + + G G G G P Q G P Sbjct: 1449 QGLPGSPGPDGPPGPMGPPGLPGLKGDSGPKGEKGHPGLIGLIGPPGEQGEKGDRGLPGP 1508 Query: 639 PGDLLPRRMGGSGLPADCGPHDPSLAP--PPPPGGSGVLFRGPLQEPMRMPGEGHVPALP 696 G P+ G G+ GP P P P PPG G +G P GE P P Sbjct: 1509 QGSSGPK--GEQGITGPSGPIGPPGPPGLPGPPGPKGA--KGS-SGPTGPKGEAGHPGPP 1563 Query: 697 SP 698 P Sbjct: 1564 GP 1565 Score = 41.2 bits (95), Expect = 0.007 Identities = 96/399 (24%), Positives = 121/399 (30%), Gaps = 82/399 (20%) Query: 37 PAFHTGGPPGPVDPAMSALGEPPILGMNMEPYGFHARGHSELHAGGLQAQPVHGFFGGQQ 96 P GPPGP PA L PP M P G ++ G + P G Sbjct: 463 PGMLIEGPPGPEGPA--GLPGPP---GTMGPTG-------QVGDPGERGPPGRPGLPGAD 510 Query: 97 PHHGHPGSHHPHQHHPHFGGNFGGPDPGASC--------LHGGRL--------LGYGGAA 140 G PG+ GG+ G P S L RL +G G Sbjct: 511 GLPGPPGTMLMLPFRFGGGGDAGSKGPMVSAQESQAQAILQQARLALRGPAGPMGLTGRP 570 Query: 141 GGLGSQPPFAEGYEHMAESQGPES----FGPQRPGNLPDFHSSGASSHAVPAPCLPLDQS 196 G +G PP + G + GP+ GP P P S A +P Sbjct: 571 GPVG--PPGSGGLKGEPGDVGPQGPRGVQGPPGPAGKPGRRGRAGSD---GARGMPGQTG 625 Query: 197 PNRAASFHGLPSSSGSDSHSLEPRRVTNQGAVDSLEYNYPGEAPSGHFDMFSPSDSEGQL 256 P F GL G H +P P P D D Sbjct: 626 PKGDRGFDGLAGLPGEKGHRGDPG---------------PSGPPGPPGDDGERGDDGEVG 670 Query: 257 PHYAAGRQVPGGAFPGASAMPRAAGMVGLSKMHAQP-PQQQPQQQQQPQQQQQQHGVFFE 315 P G P G G P G G++ M QP P+ Q +P QQ + Sbjct: 671 PRGLPGEPGPRGLL-GPKGPPGPPGPPGVTGMDGQPGPKGNVGPQGEPGPPGQQGNPGAQ 729 Query: 316 RFSGARKMPVGLEPSVGSRHPLMQPPQQAPP--------PPQQQPPQQPPQQQPPPPPGL 367 G P G G + PL +P P P ++ PP + Q PP P G Sbjct: 730 GLPG----PQGAIGPPGEKGPLGKPGLPGMPGADGPPGHPGKEGPPGEKGGQGPPGPQG- 784 Query: 368 LVRQNSCPPALPRPQ--------QGEAGTPSGGLQDGGP 398 P P P+ +G GT +DG P Sbjct: 785 -------PIGYPGPRGVKGADGIRGLKGTKGEKGEDGFP 816 Score = 40.4 bits (93), Expect = 0.011 Identities = 64/273 (23%), Positives = 84/273 (30%), Gaps = 58/273 (21%) Query: 885 PGAPGPGGPSGTSSSGSKASGPPNPPAQGDGTSLSPNYTLESTSGND------------- 931 P PG G TS++ + S P PP L +T E+ D Sbjct: 367 PTDPGAGAEIPTSTADTSNSSNPAPPPGEGADDLEGEFTEETIRNLDENYYDPYYDPTSS 426 Query: 932 ------GKPVSG-------GGGRGRGRRKRDSGHVSPGTFFDKYSAAPDSGGAPGVSPGQ 978 G P + GG RG +K + + PG + G PG PG Sbjct: 427 PSEIGPGMPANQDTIYEGIGGPRGEKGQKGEPAIIEPGMLIEGPPGPEGPAGLPG-PPGT 485 Query: 979 QQASGAAVGGSSAGETRGAPTPHEKALTSPSWGKGAELLLGDQPDLIGSLDGGAKSDSSS 1038 +G G P L P G L+L P G GG + S Sbjct: 486 MGPTGQVGDPGERGPPGRPGLPGADGLPGPP---GTMLML---PFRFG---GGGDAGSKG 536 Query: 1039 PNVGEFASDEVSTSYANEDEVSSSSDNPQALVKASRSPLVTGSPKLPPRGVGAGEHGPKA 1098 P V S+ QA+++ +R L P G+ G GP Sbjct: 537 PMV------------------SAQESQAQAILQQARLAL---RGPAGPMGL-TGRPGPVG 574 Query: 1099 PPPALGLGIMSNSTSTPDSYGGGGGPGHPGTPG 1131 PP + GL G G PG G PG Sbjct: 575 PPGSGGLKGEPGDVGPQGPRGVQGPPGPAGKPG 607 Score = 40.0 bits (92), Expect = 0.015 Identities = 73/295 (24%), Positives = 91/295 (30%), Gaps = 59/295 (20%) Query: 872 GNPGSDYFPGGTAPGAPGPGGP--------SGTSSSGSKASGPPNPPAQGDGTSLSPNYT 923 G PG PG A G PGP G G +GSK +Q Sbjct: 499 GPPGRPGLPG--ADGLPGPPGTMLMLPFRFGGGGDAGSKGPMVSAQESQAQAILQQARLA 556 Query: 924 LESTSGNDGKPVSGG--GGRGRGRRKRDSGHVSPGTFFDKYSAAPDSGGAPGVS--PGQQ 979 L +G G G G G G K + G V P G PG + PG++ Sbjct: 557 LRGPAGPMGLTGRPGPVGPPGSGGLKGEPGDVGP-------QGPRGVQGPPGPAGKPGRR 609 Query: 980 QASGAAVGGSSAGETRGAPTPHEKALTSPSWGKGAELLLGDQPDLIGSLDGGAKSDSSSP 1039 G + + RG P T P +G + L G + D G P Sbjct: 610 -------GRAGSDGARGMP-----GQTGPKGDRGFDGLAGLPGEKGHRGDPGPSGPPGPP 657 Query: 1040 -NVGEFASDEVSTSYANEDEVSSSSDNPQALVKASRSPLVTGSPKLPPRGVGAGEHGPKA 1098 + GE D P+ L P PK PP GP Sbjct: 658 GDDGERGDD--------------GEVGPRGL-PGEPGPRGLLGPKGPP--------GPPG 694 Query: 1099 PPPALGLGIMSNSTSTPDSYGGGGGPGHPGTPGLEQVRTPTSSSGAPPPDEIHPL 1153 PP G+ G G PG G PG + + P + G PP E PL Sbjct: 695 PPGVTGMDGQPGPKGNVGPQGEPGPPGQQGNPGAQGLPGPQGAIG--PPGEKGPL 747 Score = 32.0 bits (71), Expect = 4.0 Identities = 51/220 (23%), Positives = 76/220 (34%), Gaps = 27/220 (12%) Query: 996 GAPTPHEKALTS------PSWGKGAELLLGD-QPDLIGSLDGGAKSDSSSPNVGEFASDE 1048 GA P A TS P G+GA+ L G+ + I +LD P + E Sbjct: 373 GAEIPTSTADTSNSSNPAPPPGEGADDLEGEFTEETIRNLDENYYDPYYDPTS---SPSE 429 Query: 1049 VSTSY-ANEDEVSSSSDNPQALVKASRSPLVTGSPKLPPRGVGAGEHGPKAPPPALGLGI 1107 + AN+D + P+ P + + P + G GP+ P G Sbjct: 430 IGPGMPANQDTIYEGIGGPRGEKGQKGEPAI-----IEPGMLIEGPPGPEGPAGLPGPPG 484 Query: 1108 MSNSTSTPDSYGGGGGPGHPGTPGLEQVRTPTSS---------SGAPPPDEIHPLEILQA 1158 T G G PG PG PG + + P + G + + ++ Sbjct: 485 TMGPTGQVGDPGERGPPGRPGLPGADGLPGPPGTMLMLPFRFGGGGDAGSKGPMVSAQES 544 Query: 1159 QIQLQRQQFSISEDQPLGLKG--GKKGECAVGASGAQNGD 1196 Q Q QQ ++ P G G G+ G SG G+ Sbjct: 545 QAQAILQQARLALRGPAGPMGLTGRPGPVGPPGSGGLKGE 584 >gi|22027597 alpha 1 type XIII collagen isoform 13 [Homo sapiens] Length = 690 Score = 94.4 bits (233), Expect = 7e-19 Identities = 152/561 (27%), Positives = 200/561 (35%), Gaps = 118/561 (21%) Query: 681 QEPMRMPGEGHVPALPSPGLQFG-----GSLGGLGQLQSPG-AGVGLPSAASERRPPPPD 734 + P PG PA P + G G++G G++ SPG AG+ + R PP Sbjct: 109 EAPKTSPGCNCPPAFQGPTGRPGLPGDKGAIGMPGRVGSPGDAGLSIIGP----RGPPGQ 164 Query: 735 FATSALGGQPGFPFGAAGRQSTPHSGP----GVNSPPSAGGGGGSSGGGGGGGAYPPQPD 790 T G PG P G G+ H GP G+ PP G G G G G YP + Sbjct: 165 PGTRGFPGFPG-PIGLDGKPG--HPGPKGDMGLTGPPGQPGPQGQKGEKGQCGEYPHR-- 219 Query: 791 FQPSQRTSASKLGALSLGSFNKPSSKDNLFGQSCLAALSTACQN--MIASLGAPNLNVTF 848 CL+++ A ++ +IA P LN + Sbjct: 220 --------------------------------ECLSSMPAALRSSQIIALKLLPLLN-SV 246 Query: 849 NKKNPPEGKRKLSQNETDGAAVAGNPGSDYFPGGTAP----GAPGPGGPSGTSSSGSKAS 904 PP KR+ Q E A++ G PG PG + P G PGP GP G Sbjct: 247 RLAPPPVIKRRTFQGEQSQASIQGPPGPPGPPGPSGPLGHPGLPGPMGPPGLP------- 299 Query: 905 GPPNPPAQGDGTSLSPNYTLESTSGNDGKP----VSGGGGRGRGRRKRDSGHVSPGTFFD 960 GPP P +GD + + + G G P G G K + G PGT + Sbjct: 300 GPPGP--KGD-PGIQGYHGRKGERGMPGMPGKHGAKGAPGIAVAGMKGEPG--IPGTKGE 354 Query: 961 KYSAAPDSGGAPGVSPGQQQASGAAVGGSSAGETRGAPTPHEKALTSPSWGKGAELLLGD 1020 K A S G PG+ GQ+ G A G+S G RG P P L P KG + G Sbjct: 355 K--GAEGSPGLPGLL-GQKGEKGDA--GNSIGGGRGEPGP--PGLPGPPGPKGEAGVDGQ 407 Query: 1021 -----QPDLIGSLDG-------GAKSDSSSPNVGEFASDEVSTSYANEDEVSSSSDNPQA 1068 QP G G K P GE + + A ++ + + P Sbjct: 408 VGPPGQPGDKGERGAAGEQGPDGPKGSKGEPGKGEMVDYNGNINEALQEIRTLALMGPPG 467 Query: 1069 LVKASRSPLVTGSPK------LPPRGVGAGEHGPKAPPPALGLGIMSNSTSTPDSYGGGG 1122 L P G P LP GE GP+ P +G G G Sbjct: 468 LPGQIGPPGAPGIPGQKGEIGLPGPPGHDGEKGPRGKPGDMGPPGPQGPPGKDGPPGVKG 527 Query: 1123 GPGHPGTPGLEQVRTPTSSSGAPPPDEIHPLEILQAQIQLQRQQFSISEDQPLGLKG--G 1180 GHPG+PG + + T +G+P P P P GL+G G Sbjct: 528 ENGHPGSPGEKGEKGETGQAGSPVPGLPGP----------------EGPPGPPGLQGVPG 571 Query: 1181 KKGECAV-GASGAQNGDSELG 1200 KGE + GA G + E G Sbjct: 572 PKGEAGLDGAKGEKGFQGEKG 592 Score = 57.4 bits (137), Expect = 9e-08 Identities = 141/552 (25%), Positives = 177/552 (32%), Gaps = 97/552 (17%) Query: 271 PGASAMPRAAGMVGLSKMHAQPPQQQ------PQQQQQPQQQQQQHGVFFE--RFSGARK 322 PG P G +GL P + P Q PQ Q+ + G E Sbjct: 165 PGTRGFPGFPGPIGLDGKPGHPGPKGDMGLTGPPGQPGPQGQKGEKGQCGEYPHRECLSS 224 Query: 323 MPVGLEPS---VGSRHPLMQPPQQAPPPPQQQPPQQPPQQQ--------PPPPPGLLVRQ 371 MP L S PL+ + APPP ++ Q Q Q PP PPG Sbjct: 225 MPAALRSSQIIALKLLPLLNSVRLAPPPVIKRRTFQGEQSQASIQGPPGPPGPPG----- 279 Query: 372 NSCP---PALPRPQQGEAGTPSGGLQDGGPMLPSQHAQFEYPIHRLENRSMHPYSEPVFS 428 S P P LP P G G P G P + H R R M P Sbjct: 280 PSGPLGHPGLPGPM-GPPGLPGPPGPKGDPGIQGYHG-------RKGERGM-----PGMP 326 Query: 429 MQHPPPQQAPNQRLQHFDAPPYMNVAKRPRF--DFPGSAGVDRCASWNGSMHNGALDNHL 486 +H + AP + P + K + PG G+ G N Sbjct: 327 GKHGA-KGAPGIAVAGMKGEPGIPGTKGEKGAEGSPGLPGLLGQKGEKGDAGNSIGGGRG 385 Query: 487 SPSAYPGLPGEFTPPVPDSFPS-----GPPLQHPAPDHQSLQQQQQQQQQQQQQQQQQQQ 541 P PGLPG PP P GPP Q P + +Q + + + + Sbjct: 386 EPGP-PGLPG---PPGPKGEAGVDGQVGPPGQ-PGDKGERGAAGEQGPDGPKGSKGEPGK 440 Query: 542 QQQQQQQQQRQNAALMIKQMASRNQQQRLRQPNL-AQLGHPGDVGQGGLVHGGPVGGLAQ 600 + A I+ +A + P L Q+G PG G G G +G Sbjct: 441 GEMVDYNGNINEALQEIRTLAL------MGPPGLPGQIGPPGAPGIPG--QKGEIGLPGP 492 Query: 601 PNFEREGGSTGA-GRLGTFEQQAPHLAQESAWFSGPHPPPGDLLPRRMGGSGLPADCGPH 659 P + E G G G +G Q P G + PG P G G G Sbjct: 493 PGHDGEKGPRGKPGDMGPPGPQGPPGKDGPPGVKGENGHPGS--PGEKGEKGETGQAGSP 550 Query: 660 DPSL----APPPPPGGSGVLFRGPLQEPMRMPGEGHVPALPSPGLQFGGSLGGLGQLQSP 715 P L PP PPG GV GP E +G F G G G L P Sbjct: 551 VPGLPGPEGPPGPPGLQGV--PGPKGEAGLDGAKGEKG--------FQGEKGDRGPLGLP 600 Query: 716 GAG--VGLPSAASERRPPPPDFATSALGGQPGF--PFGAAGRQSTPHSGPGVNSPPSAGG 771 G +G+P A + G PG P GAAG PG++ PP G Sbjct: 601 GTPGPIGVPGPAGPK-------GERGSKGDPGMTGPTGAAGL-------PGLHGPPGDKG 646 Query: 772 GGGSSGGGGGGG 783 G G G G Sbjct: 647 NRGERGKKGSRG 658 Score = 55.5 bits (132), Expect = 3e-07 Identities = 140/556 (25%), Positives = 172/556 (30%), Gaps = 84/556 (15%) Query: 632 FSGPHPPPGDLLPRRMGGSGLPADCG-PHDPSLA---PPPPPGGSGVL----FRGP--LQ 681 F GP PG LP G G+P G P D L+ P PPG G F GP L Sbjct: 123 FQGPTGRPG--LPGDKGAIGMPGRVGSPGDAGLSIIGPRGPPGQPGTRGFPGFPGPIGLD 180 Query: 682 EPMRMPGEGHVPALPSPGLQFG--GSLGGLGQ---------LQSPGAGVG---------L 721 PG L P Q G G G GQ L S A + L Sbjct: 181 GKPGHPGPKGDMGLTGPPGQPGPQGQKGEKGQCGEYPHRECLSSMPAALRSSQIIALKLL 240 Query: 722 PSAASERRPPPPDFATSALGGQPGFPFGAAGRQSTPHSGPGVNSPPSAGGGGGSSGGGGG 781 P S R PPP G+ Q++ PG PP G G G G Sbjct: 241 PLLNSVRLAPPPVIKRRTFQGEQS--------QASIQGPPGPPGPPGPSGPLGHPGLPGP 292 Query: 782 GGAY----PPQPDFQPSQRTSASKLGALSL-GSFNKPSSKDNLFGQSCLAALSTACQNMI 836 G PP P P + + G + G K +K A A M Sbjct: 293 MGPPGLPGPPGPKGDPGIQGYHGRKGERGMPGMPGKHGAK---------GAPGIAVAGMK 343 Query: 837 ASLGAPNLNVTFNKKNPPEGKRKLSQNETDGAAVAGNPGSDYFPGGTAPGAPGPGGPSGT 896 G P + P L Q G A G PG PG PGP GP G Sbjct: 344 GEPGIPGTKGEKGAEGSPGLPGLLGQKGEKGDAGNSIGGGRGEPG--PPGLPGPPGPKGE 401 Query: 897 SSSGSKASGPPNPPAQGDGTSLSPNYTLESTSGNDGKPVSGGGGRGRGRRKRDSGHVSPG 956 + + GPP P + + G+ G+P G+G +G+++ Sbjct: 402 AGVDGQV-GPPGQPGDKGERGAAGEQGPDGPKGSKGEP-------GKGEMVDYNGNINEA 453 Query: 957 TFFDKYSAAPDSGGAPGVSPGQQQASGAAVGGSSAGETRGAPTPHEKALTSPSWGKGAEL 1016 + A G PG+ PGQ GA GE G P P KG Sbjct: 454 LQEIRTLALM---GPPGL-PGQIGPPGAPGIPGQKGEI-GLPGP-----PGHDGEKGPRG 503 Query: 1017 LLGDQ----PDLIGSLDG--GAKSDSSSPNVGEFASDEVSTSYANEDEVS-SSSDNPQAL 1069 GD P DG G K ++ P ++ T A + P Sbjct: 504 KPGDMGPPGPQGPPGKDGPPGVKGENGHPGSPGEKGEKGETGQAGSPVPGLPGPEGPPGP 563 Query: 1070 VKASRSPLVTGSPKLPPRGVGAGEHGPKAPPPALGLGIMSNSTSTPDSYGGGGGPGHPGT 1129 P G L G G K LGL P G G G G Sbjct: 564 PGLQGVPGPKGEAGLDGAKGEKGFQGEKGDRGPLGLPGTPGPIGVPGPAGPKGERGSKGD 623 Query: 1130 PGLEQVRTPTSSSGAP 1145 PG+ PT ++G P Sbjct: 624 PGM---TGPTGAAGLP 636 Score = 42.7 bits (99), Expect = 0.002 Identities = 84/371 (22%), Positives = 104/371 (28%), Gaps = 108/371 (29%) Query: 579 GHPGDVGQGGLVH----GGPVGGLAQPNFEREGGSTGAGRLGTFEQQAPHLAQESAWFSG 634 G PGD G+ G GP G +P G G + + QE + Sbjct: 412 GQPGDKGERGAAGEQGPDGPKGSKGEP---------GKGEMVDYNGNINEALQEIRTLAL 462 Query: 635 PHPP--PGDLLPRRMGGSGLPADCGPHDPSLAPPPPPGGSGVLFRGPLQEPMRMPGEGHV 692 PP PG + P G G+P G + P PPG G +GP +P Sbjct: 463 MGPPGLPGQIGPP--GAPGIPGQKG----EIGLPGPPGHDGE--KGPRGKP--------- 505 Query: 693 PALPSPGLQFGGSLGGLGQLQSPGAGVGLPSAASERRPP--PPDFATSALGGQPGFPFGA 750 G +G G PG G P E P P + GQ G P Sbjct: 506 -----------GDMGPPGPQGPPGKD-GPPGVKGENGHPGSPGEKGEKGETGQAGSPVPG 553 Query: 751 AGRQSTPHSGPGVNSPPSAGGGGGSSGGGGGGGAYPPQPDFQPSQRTSASKLGALSLGSF 810 P PG+ P G G G G G + D P Sbjct: 554 LPGPEGPPGPPGLQGVPGPKGEAGLDGAKGEKGFQGEKGDRGP----------------- 596 Query: 811 NKPSSKDNLFGQSCLAALSTACQNMIASLGAPNLNVTFNKKNP--PEGKRKLSQNETDGA 868 LG P P P+G+R Sbjct: 597 ----------------------------LGLPGTPGPIGVPGPAGPKGER---------- 618 Query: 869 AVAGNPGSDYFPGGT-APGAPGPGGPSGTSSS-GSKASGPPNPPAQGDGTSLSPNYTLES 926 G+ G G T A G PG GP G + G + P G +P Sbjct: 619 ---GSKGDPGMTGPTGAAGLPGLHGPPGDKGNRGERGKKGSRGPKGDKGDQGAPGLDAPC 675 Query: 927 TSGNDGKPVSG 937 G DG PV G Sbjct: 676 PLGEDGLPVQG 686 Score = 35.4 bits (80), Expect = 0.36 Identities = 97/391 (24%), Positives = 125/391 (31%), Gaps = 53/391 (13%) Query: 43 GPPGPVDPAMSALGEPPILGMNMEPYGFHARGHSELHAGGLQAQP-VHGFFG--GQQPHH 99 GPPGP P+ LG P + G M P G G + P + G+ G G++ Sbjct: 273 GPPGPPGPS-GPLGHPGLPGP-MGPPGLPG-------PPGPKGDPGIQGYHGRKGERGMP 323 Query: 100 GHPGSHHPHQHHPHFG--GNFGGPD-PGASCLHGGRLLGYGGAAGGLGSQPPFAEGYEHM 156 G PG H + P G G P PG G G G G LG + + + Sbjct: 324 GMPGKHGA-KGAPGIAVAGMKGEPGIPGTKGEKGAE--GSPGLPGLLGQKGEKGDAGNSI 380 Query: 157 AESQGPESFGPQRPGNLPDFHSSGASSHAVPAPCLPLDQSPNRAASFHGLPSSSGSDSHS 216 +G E P PG +G P P P D+ AA G GS Sbjct: 381 GGGRG-EPGPPGLPGPPGPKGEAGVDGQVGP-PGQPGDKGERGAAGEQGPDGPKGSKGEP 438 Query: 217 LEPRRVTNQGAVDSLEYNYPGEAPSGHFDMFSPSDSEGQL-PHYAAGRQVPGGAFPGASA 275 + V G ++ A G P GQ+ P A G +PG G Sbjct: 439 GKGEMVDYNGNINEALQEIRTLALMG------PPGLPGQIGPPGAPG--IPGQK--GEIG 488 Query: 276 MPRAAGMVGLSKMHAQPPQQQPQQQQQPQQQQQQHGVFFERF---SGARKMPVGLEPSVG 332 +P G G +P P Q P + GV E S K G G Sbjct: 489 LPGPPGHDGEKGPRGKPGDMGPPGPQGPPGKDGPPGVKGENGHPGSPGEKGEKGETGQAG 548 Query: 333 SRHPLMQPPQQAPPPPQQQPPQQPPQQQ-------------------PPPPPGLLVRQNS 373 S P + P+ P PP Q P + P PG Sbjct: 549 SPVPGLPGPEGPPGPPGLQGVPGPKGEAGLDGAKGEKGFQGEKGDRGPLGLPGTPGPIGV 608 Query: 374 CPPALPRPQQGEAGTPSGGLQDGGPMLPSQH 404 PA P+ ++G G P G LP H Sbjct: 609 PGPAGPKGERGSKGDPGMTGPTGAAGLPGLH 639 Score = 31.2 bits (69), Expect = 6.9 Identities = 60/261 (22%), Positives = 87/261 (33%), Gaps = 41/261 (15%) Query: 262 GRQVPGGAFPGASAMPRAAGMVGLSKMHAQPPQQQPQQQQQPQQQQQQHGVFFERFSGAR 321 GR PG PG P G G+ P Q + ++ +Q G G++ Sbjct: 383 GRGEPGP--PGLPGPPGPKGEAGVDGQVGPPGQPGDKGERGAAGEQGPDGP-----KGSK 435 Query: 322 KMPVGLEPSVGSRHPLMQPPQQAPPPPQQQPPQQPPQQQPPPPPGLLVRQNSC----PPA 377 P G V + + Q+ PP P Q PP PG+ ++ PP Sbjct: 436 GEP-GKGEMVDYNGNINEALQEIRTLALMGPPGLPGQIGPPGAPGIPGQKGEIGLPGPPG 494 Query: 378 L-----PRPQQGEAGTP---SGGLQDGGPMLPSQHAQFEYPIHRLENRSMHPYSEPVFSM 429 PR + G+ G P +DG P + ++ P + E PV + Sbjct: 495 HDGEKGPRGKPGDMGPPGPQGPPGKDGPPGVKGENGHPGSPGEKGEKGETGQAGSPVPGL 554 Query: 430 QHPPPQQAPNQRLQHFDAPPYMNVAKRPRFDFPGSAGVDRCASWNGSMHNGALDNHLSPS 489 P P+ P PP + P+ G AG+D G P Sbjct: 555 --PGPEGPP--------GPPGLQGVPGPK----GEAGLDGAKGEKGFQGE---KGDRGPL 597 Query: 490 AYPGLPGEFTPPVPDSFPSGP 510 PG PG P+ P+GP Sbjct: 598 GLPGTPG----PIGVPGPAGP 614 >gi|22027580 alpha 1 type XIII collagen isoform 6 [Homo sapiens] Length = 702 Score = 94.4 bits (233), Expect = 7e-19 Identities = 152/561 (27%), Positives = 200/561 (35%), Gaps = 118/561 (21%) Query: 681 QEPMRMPGEGHVPALPSPGLQFG-----GSLGGLGQLQSPG-AGVGLPSAASERRPPPPD 734 + P PG PA P + G G++G G++ SPG AG+ + R PP Sbjct: 109 EAPKTSPGCNCPPAFQGPTGRPGLPGDKGAIGMPGRVGSPGDAGLSIIGP----RGPPGQ 164 Query: 735 FATSALGGQPGFPFGAAGRQSTPHSGP----GVNSPPSAGGGGGSSGGGGGGGAYPPQPD 790 T G PG P G G+ H GP G+ PP G G G G G YP + Sbjct: 165 PGTRGFPGFPG-PIGLDGKPG--HPGPKGDMGLTGPPGQPGPQGQKGEKGQCGEYPHR-- 219 Query: 791 FQPSQRTSASKLGALSLGSFNKPSSKDNLFGQSCLAALSTACQN--MIASLGAPNLNVTF 848 CL+++ A ++ +IA P LN + Sbjct: 220 --------------------------------ECLSSMPAALRSSQIIALKLLPLLN-SV 246 Query: 849 NKKNPPEGKRKLSQNETDGAAVAGNPGSDYFPGGTAP----GAPGPGGPSGTSSSGSKAS 904 PP KR+ Q E A++ G PG PG + P G PGP GP G Sbjct: 247 RLAPPPVIKRRTFQGEQSQASIQGPPGPPGPPGPSGPLGHPGLPGPMGPPGLP------- 299 Query: 905 GPPNPPAQGDGTSLSPNYTLESTSGNDGKP----VSGGGGRGRGRRKRDSGHVSPGTFFD 960 GPP P +GD + + + G G P G G K + G PGT + Sbjct: 300 GPPGP--KGD-PGIQGYHGRKGERGMPGMPGKHGAKGAPGIAVAGMKGEPG--IPGTKGE 354 Query: 961 KYSAAPDSGGAPGVSPGQQQASGAAVGGSSAGETRGAPTPHEKALTSPSWGKGAELLLGD 1020 K A S G PG+ GQ+ G A G+S G RG P P L P KG + G Sbjct: 355 K--GAEGSPGLPGLL-GQKGEKGDA--GNSIGGGRGEPGP--PGLPGPPGPKGEAGVDGQ 407 Query: 1021 -----QPDLIGSLDG-------GAKSDSSSPNVGEFASDEVSTSYANEDEVSSSSDNPQA 1068 QP G G K P GE + + A ++ + + P Sbjct: 408 VGPPGQPGDKGERGAAGEQGPDGPKGSKGEPGKGEMVDYNGNINEALQEIRTLALMGPPG 467 Query: 1069 LVKASRSPLVTGSPK------LPPRGVGAGEHGPKAPPPALGLGIMSNSTSTPDSYGGGG 1122 L P G P LP GE GP+ P +G G G Sbjct: 468 LPGQIGPPGAPGIPGQKGEIGLPGPPGHDGEKGPRGKPGDMGPPGPQGPPGKDGPPGVKG 527 Query: 1123 GPGHPGTPGLEQVRTPTSSSGAPPPDEIHPLEILQAQIQLQRQQFSISEDQPLGLKG--G 1180 GHPG+PG + + T +G+P P P P GL+G G Sbjct: 528 ENGHPGSPGEKGEKGETGQAGSPVPGLPGP----------------EGPPGPPGLQGVPG 571 Query: 1181 KKGECAV-GASGAQNGDSELG 1200 KGE + GA G + E G Sbjct: 572 PKGEAGLDGAKGEKGFQGEKG 592 Score = 58.5 bits (140), Expect = 4e-08 Identities = 137/548 (25%), Positives = 167/548 (30%), Gaps = 78/548 (14%) Query: 632 FSGPHPPPGDLLPRRMGGSGLPADCG-PHDPSLA---PPPPPGGSGVL----FRGP--LQ 681 F GP PG LP G G+P G P D L+ P PPG G F GP L Sbjct: 123 FQGPTGRPG--LPGDKGAIGMPGRVGSPGDAGLSIIGPRGPPGQPGTRGFPGFPGPIGLD 180 Query: 682 EPMRMPGEGHVPALPSPGLQFG--GSLGGLGQ---------LQSPGAGVG---------L 721 PG L P Q G G G GQ L S A + L Sbjct: 181 GKPGHPGPKGDMGLTGPPGQPGPQGQKGEKGQCGEYPHRECLSSMPAALRSSQIIALKLL 240 Query: 722 PSAASERRPPPPDFATSALGGQPGFPFGAAGRQSTPHSGPGVNSPPSAGGGGGSSGGGGG 781 P S R PPP G+ Q++ PG PP G G G G Sbjct: 241 PLLNSVRLAPPPVIKRRTFQGEQS--------QASIQGPPGPPGPPGPSGPLGHPGLPGP 292 Query: 782 GGAY----PPQPDFQPSQRTSASKLGALSL-GSFNKPSSKDNLFGQSCLAALSTACQNMI 836 G PP P P + + G + G K +K A A M Sbjct: 293 MGPPGLPGPPGPKGDPGIQGYHGRKGERGMPGMPGKHGAK---------GAPGIAVAGMK 343 Query: 837 ASLGAPNLNVTFNKKNPPEGKRKLSQNETDGAAVAGNPGSDYFPGGTAPGAPGPGGPSGT 896 G P + P L Q G A G PG PG PGP GP G Sbjct: 344 GEPGIPGTKGEKGAEGSPGLPGLLGQKGEKGDAGNSIGGGRGEPG--PPGLPGPPGPKGE 401 Query: 897 SSSGSKASGPPNPPAQGDGTSLSPNYTLESTSGNDGKPVSGGGGRGRGRRKRDSGHVSPG 956 + + GPP P + + G+ G+P G+G +G+++ Sbjct: 402 AGVDGQV-GPPGQPGDKGERGAAGEQGPDGPKGSKGEP-------GKGEMVDYNGNINEA 453 Query: 957 TFFDKYSAAPDSGGAPGVSPGQQQASGAAVGGSSAGETRGAPTPHEKALTSPSWGKGAEL 1016 + A G PG+ PGQ GA GE L P G + Sbjct: 454 LQEIRTLALM---GPPGL-PGQIGPPGAPGIPGQKGEI---------GLPGPPGHDGEKG 500 Query: 1017 LLGDQPDLIGSLDGGAKSDSSSPNV-GEFASDEVSTSYANEDEVSSSSDNPQALVKASRS 1075 G D+ G P V GE + E + L Sbjct: 501 PRGKPGDMGPPGPQGPPGKDGPPGVKGENGHPGSPGEKGEKGETGQAGSPVPGLPGPEGP 560 Query: 1076 PLVTGSPKLPPRGVGAGEHGPKAPPPALGLGIMSNSTSTPDSYGGGGGPGHPGTPGLEQV 1135 P G +P AG G K G P + G G PG PGTPG V Sbjct: 561 PGPPGLQGVPGPKGEAGLDGAKGEKGFQGEKGDRGPLGLPGASGLDGRPGPPGTPGPIGV 620 Query: 1136 RTPTSSSG 1143 P G Sbjct: 621 PGPAGPKG 628 Score = 57.8 bits (138), Expect = 7e-08 Identities = 144/558 (25%), Positives = 177/558 (31%), Gaps = 97/558 (17%) Query: 271 PGASAMPRAAGMVGLSKMHAQPPQQQ------PQQQQQPQQQQQQHGVFFE--RFSGARK 322 PG P G +GL P + P Q PQ Q+ + G E Sbjct: 165 PGTRGFPGFPGPIGLDGKPGHPGPKGDMGLTGPPGQPGPQGQKGEKGQCGEYPHRECLSS 224 Query: 323 MPVGLEPS---VGSRHPLMQPPQQAPPPPQQQPPQQPPQQQ--------PPPPPGLLVRQ 371 MP L S PL+ + APPP ++ Q Q Q PP PPG Sbjct: 225 MPAALRSSQIIALKLLPLLNSVRLAPPPVIKRRTFQGEQSQASIQGPPGPPGPPG----- 279 Query: 372 NSCP---PALPRPQQGEAGTPSGGLQDGGPMLPSQHAQFEYPIHRLENRSMHPYSEPVFS 428 S P P LP P G G P G P + H R R M P Sbjct: 280 PSGPLGHPGLPGPM-GPPGLPGPPGPKGDPGIQGYHG-------RKGERGM-----PGMP 326 Query: 429 MQHPPPQQAPNQRLQHFDAPPYMNVAKRPRF--DFPGSAGVDRCASWNGSMHNGALDNHL 486 +H + AP + P + K + PG G+ G N Sbjct: 327 GKHGA-KGAPGIAVAGMKGEPGIPGTKGEKGAEGSPGLPGLLGQKGEKGDAGNSIGGGRG 385 Query: 487 SPSAYPGLPGEFTPPVPDSFPS-----GPPLQHPAPDHQSLQQQQQQQQQQQQQQQQQQQ 541 P PGLPG PP P GPP Q P + +Q + + + + Sbjct: 386 EPGP-PGLPG---PPGPKGEAGVDGQVGPPGQ-PGDKGERGAAGEQGPDGPKGSKGEPGK 440 Query: 542 QQQQQQQQQRQNAALMIKQMASRNQQQRLRQPNL-AQLGHPGDVGQGGLVHGGPVGGLAQ 600 + A I+ +A + P L Q+G PG G G G +G Sbjct: 441 GEMVDYNGNINEALQEIRTLAL------MGPPGLPGQIGPPGAPGIPG--QKGEIGLPGP 492 Query: 601 PNFEREGGSTGA-GRLGTFEQQAPHLAQESAWFSGPHPPPGDLLPRRMGGSGLPADCGPH 659 P + E G G G +G Q P G + PG P G G G Sbjct: 493 PGHDGEKGPRGKPGDMGPPGPQGPPGKDGPPGVKGENGHPGS--PGEKGEKGETGQAGSP 550 Query: 660 DPSL----APPPPPGGSGVLFRGPLQEPMRMPGEGHVPALPSPGLQFGGSLGGLGQLQSP 715 P L PP PPG GV GP E +G F G G G L P Sbjct: 551 VPGLPGPEGPPGPPGLQGV--PGPKGEAGLDGAKGEKG--------FQGEKGDRGPLGLP 600 Query: 716 GAGVGLPSAASERRPPPPDFATSALG--------GQPGF--PFGAAGRQSTPHSGPGVNS 765 GA GL P P G G PG P GAAG PG++ Sbjct: 601 GAS-GLDGRPGPPGTPGPIGVPGPAGPKGERGSKGDPGMTGPTGAAGL-------PGLHG 652 Query: 766 PPSAGGGGGSSGGGGGGG 783 PP G G G G G Sbjct: 653 PPGDKGNRGERGKKGSRG 670 Score = 57.0 bits (136), Expect = 1e-07 Identities = 98/378 (25%), Positives = 124/378 (32%), Gaps = 45/378 (11%) Query: 579 GHPGDVGQGGLVHGGPVGGLAQPNFER--EGGSTGAGR--LGTFEQQAPHLAQESAWFSG 634 G PG G+ G + GL E+ G S G GR G P + A G Sbjct: 347 GIPGTKGEKGAEGSPGLPGLLGQKGEKGDAGNSIGGGRGEPGPPGLPGPPGPKGEAGVDG 406 Query: 635 PHPPPGDLLPRRMGGSGLPADCGPHDPSLAPPPPPGGSGVLFRGPLQEPMRMPGEGHVPA 694 PPG P G G + GP P + P G V + G + E ++ E A Sbjct: 407 QVGPPGQ--PGDKGERGAAGEQGPDGPKGSKGEPGKGEMVDYNGNINEALQ---EIRTLA 461 Query: 695 LPSPGLQFGGSLGGLGQLQSPGAGVGLPSAASERRPPPPDFATSALG--GQPGFPFGAAG 752 L P G GQ+ PGA G+P E P P G G+PG G G Sbjct: 462 LMGPP-------GLPGQIGPPGAP-GIPGQKGEIGLPGPPGHDGEKGPRGKPG-DMGPPG 512 Query: 753 RQSTP-HSGP----GVNSPPSAGGGGGSSGGGGGGGAYPPQ---PDFQPSQRTSASKLGA 804 Q P GP G N P + G G G G G+ P P+ P G Sbjct: 513 PQGPPGKDGPPGVKGENGHPGSPGEKGEKGETGQAGSPVPGLPGPEGPPGPPGLQGVPGP 572 Query: 805 LSLGSFNKPSSKDNLFGQSCLAALSTACQNMIASLGAPNLNVTFNKKNPPEGKRKLSQNE 864 + + G+ + LG P + + PP + Sbjct: 573 KGEAGLDGAKGEKGFQGE----------KGDRGPLGLPGASGLDGRPGPPGTPGPIGVPG 622 Query: 865 TDGAAVAGNPGSDYFPGGTAP----GAPGPGGPSGTSSS-GSKASGPPNPPAQGDGTSLS 919 G G GS PG T P G PG GP G + G + P G + Sbjct: 623 PAGPK--GERGSKGDPGMTGPTGAAGLPGLHGPPGDKGNRGERGKKGSRGPKGDKGDQGA 680 Query: 920 PNYTLESTSGNDGKPVSG 937 P G DG PV G Sbjct: 681 PGLDAPCPLGEDGLPVQG 698 Score = 37.7 bits (86), Expect = 0.073 Identities = 93/388 (23%), Positives = 123/388 (31%), Gaps = 62/388 (15%) Query: 43 GPPGPV-DPAMSAL-GEPPILGMNMEPYGFHARGHSELHAGGLQAQPVHGFFGGQQPHHG 100 GPPGP DP + G GM P A+G + G++ +P G++ G Sbjct: 300 GPPGPKGDPGIQGYHGRKGERGMPGMPGKHGAKGAPGIAVAGMKGEPGIPGTKGEKGAEG 359 Query: 101 HPGSHHPHQHHPHFGGNFGGPDPGASCLHGGRLLGYGGAAGGLGSQPPFAEGYEHMAESQ 160 PG P G G + + GGR G G G G PP +G + Sbjct: 360 SPGL-------PGLLGQKGEKGDAGNSIGGGR--GEPGPPGLPG--PPGPKGEAGVDGQV 408 Query: 161 GPESFGPQRPGNLPDFHSSGAS-------SHAVPAPCLPLDQSPN--------RAASFHG 205 GP P +PG+ + ++G S P +D + N R + G Sbjct: 409 GP----PGQPGDKGERGAAGEQGPDGPKGSKGEPGKGEMVDYNGNINEALQEIRTLALMG 464 Query: 206 LPSSSGSDSHSLEPRRVTNQGAVDSLEYNYPGEAPSGHFDMFSPSDSEGQL----PHYAA 261 P G P +G E PG P GH P G + P Sbjct: 465 PPGLPGQIGPPGAPGIPGQKG-----EIGLPG--PPGHDGEKGPRGKPGDMGPPGPQGPP 517 Query: 262 GRQVPGGAFPGASAMPRAAGMVGLSKMHAQ-----PPQQQPQQQQQPQQQQQQHGVFFER 316 G+ P G G + P + G G Q P P+ P Q G E Sbjct: 518 GKDGPPGV-KGENGHPGSPGEKGEKGETGQAGSPVPGLPGPEGPPGPPGLQGVPGPKGEA 576 Query: 317 FSGARKMPVGLEPSVGSRHPLMQPPQQAPPPPQQQPPQQPPQQQPPPPPGLLVRQNSCPP 376 K G + G R PL P P P P PG P Sbjct: 577 GLDGAKGEKGFQGEKGDRGPLGLPGASG----LDGRPGPPGTPGPIGVPG---------P 623 Query: 377 ALPRPQQGEAGTPSGGLQDGGPMLPSQH 404 A P+ ++G G P G LP H Sbjct: 624 AGPKGERGSKGDPGMTGPTGAAGLPGLH 651 Score = 35.0 bits (79), Expect = 0.48 Identities = 91/352 (25%), Positives = 118/352 (33%), Gaps = 54/352 (15%) Query: 43 GPPGPVDPAMSALGEPPILGMNMEPYGFHARGHSELHAGGLQAQP-VHGFFG--GQQPHH 99 GPPGP P+ LG P + G M P G G + P + G+ G G++ Sbjct: 273 GPPGPPGPS-GPLGHPGLPGP-MGPPGLPG-------PPGPKGDPGIQGYHGRKGERGMP 323 Query: 100 GHPGSHHPHQHHPHFG--GNFGGPD-PGASCLHGGRLLGYGGAAGGLGSQPPFAEGYEHM 156 G PG H + P G G P PG G G G G LG + + + Sbjct: 324 GMPGKHGA-KGAPGIAVAGMKGEPGIPGTKGEKGAE--GSPGLPGLLGQKGEKGDAGNSI 380 Query: 157 AESQGPESFGPQRPGNLPDFHSSGASSHAVPAPCLPLDQSPNRAASFHGLPSSSGSDSHS 216 +G E P PG +G P P P D+ AA G GS Sbjct: 381 GGGRG-EPGPPGLPGPPGPKGEAGVDGQVGP-PGQPGDKGERGAAGEQGPDGPKGSKGEP 438 Query: 217 LEPRRVTNQGAVDSLEYNYPGEAPSGHFDMFSPSDSEGQL-PHYAAGRQVPGGAFPGASA 275 + V G ++ A G P GQ+ P A G +PG G Sbjct: 439 GKGEMVDYNGNINEALQEIRTLALMG------PPGLPGQIGPPGAPG--IPGQK--GEIG 488 Query: 276 MPRAAGMVGLSKMHAQPPQQQPQQQQQPQQQQQQHGVFFERFSGARKMPVGLEPSVGSRH 335 +P G G +P P Q P + GV E G S G + Sbjct: 489 LPGPPGHDGEKGPRGKPGDMGPPGPQGPPGKDGPPGVKGEN---------GHPGSPGEKG 539 Query: 336 PLMQPPQQAPPPPQQQPPQQPPQQQPPPPPGLLVRQNSCPPALPRPQQGEAG 387 + Q P P P+ P P PPGL +P P +GEAG Sbjct: 540 EKGETGQAGSPVPGLPGPEGP-----PGPPGL--------QGVPGP-KGEAG 577 >gi|89363017 alpha 2 type V collagen preproprotein [Homo sapiens] Length = 1499 Score = 94.0 bits (232), Expect = 9e-19 Identities = 283/1163 (24%), Positives = 360/1163 (30%), Gaps = 255/1163 (21%) Query: 43 GPPGPVDPAMSA--LGEPPILGMNMEPYGFHARGHSELHAGGLQAQPVHGFFG-----GQ 95 G PGP+ P S G P G + EP R + G + GF G G Sbjct: 243 GDPGPMGPIGSRGPEGPPGKPGEDGEP----GRNGNPGEVGFAGSPGARGFPGAPGLPGL 298 Query: 96 QPHHGHPGSHHPHQH--HPHFGGNFGGPDP-GASCLHGGRLLGYGGAAGGLGSQ-PPFAE 151 + H GH G P P G G P GA G R G G G LG Q P Sbjct: 299 KGHRGHKGLEGPKGEVGAPGSKGEAGPTGPMGAMGPLGPR--GMPGERGRLGPQGAPGQR 356 Query: 152 GYEHMAESQGP--------ESFGPQRPGNLPDFHSSGASSHAVPAPCLPLDQSPNRAASF 203 G M GP S P PG + +GA P P S Sbjct: 357 GAHGMPGKPGPMGPLGIPGSSGFPGNPGMKGEAGPTGARGPEGPQGQRGETGPPGPVGS- 415 Query: 204 HGLPSSSGSDSHSLEPRRVTNQGAVDSLEYNYPG-EAPSGHFDMFSPSDSEGQLPHYAAG 262 GLP + G+D PG + P+G P S G Sbjct: 416 PGLPGAIGTDGT--------------------PGAKGPTGSPGTSGPPGSAGP------- 448 Query: 263 RQVPGGAFPGASAMPRAAGMVGLSKMHAQPPQQQPQQQQQPQQQQQQHGVFFERFSGARK 322 PG P S P+ G+ P + + P+ + HG+ + Sbjct: 449 ---PGSPGPQGSTGPQ-----GIRGQPGDPGVPGFKGEAGPKGEPGPHGI---------Q 491 Query: 323 MPVGLEPSVGSRHPLMQPPQQAPPPP--QQQPPQQ---PPQQQPPPPPGLLVRQNSCPPA 377 P+G G R P P PP P ++ P P P P G + + Sbjct: 492 GPIGPPGEEGKRGPRGDPGTVGPPGPVGERGAPGNRGFPGSDGLPGPKGAQGERGPVGSS 551 Query: 378 LPRPQQGEAGTPSGGLQDGGPMLPSQHAQFEYPIHRLENRSMHPYSEPVFSMQHPPPQQA 437 P+ QG+ G P G P LP P + + P P + PP Sbjct: 552 GPKGSQGDPGRP------GEPGLPGARGLTGNPGVQGPEGKLGPLGAPGEDGRPGPPGSI 605 Query: 438 PNQRLQHFDAPPYMNV-AKRPRFDFPGSAGVDRCASWNGSMHNGALDNHLSPSAYPGLPG 496 + P M + + PG G A G D + PS G PG Sbjct: 606 GIR-----GQPGSMGLPGPKGSSGDPGKPGEAGNAGVPGQRGAPGKDGEVGPSGPVGPPG 660 Query: 497 ------EFTPPVPDSF-----PSGPPLQHPAPDHQSLQQQQQQQQQQQQQQQQQQQQQQQ 545 E PP P F P GPP + P Q + + ++ ++ Sbjct: 661 LAGERGEQGPPGPTGFQGLPGPPGPPGEGGKPGDQGVPGDPGAVGPLGPRGERGNPGERG 720 Query: 546 QQQQQRQNAALMIKQMASRNQQQRLRQPNLAQLGHPGDVGQGGL--------VHGGPV-- 595 + K MA + + + G PGD G GL + G P Sbjct: 721 EPGITGLPGE---KGMAGGHGPDGPKG-SPGPSGTPGDTGPPGLQGMPGERGIAGTPGPK 776 Query: 596 ---GGLAQPNFEREGGSTGA-GRLGTFEQQAPHLAQESAWFSGPHPPPGDLLPRRM---- 647 GG+ + E G+ GA G G P +GP G+ PR + Sbjct: 777 GDRGGIGEKGAEGTAGNDGARGLPGPLGPPGP---------AGPTGEKGEPGPRGLVGPP 827 Query: 648 GGSGLPADCGPHDPSLA-----PPPPPGGSGVLFRGPLQEPMRM-----PGEGHVPALPS 697 G G P G + P+ A P P G GV +G EP + PG + P Sbjct: 828 GSRGNPGSRGENGPTGAVGFAGPQGPDGQPGV--KGEPGEPGQKGDAGSPGPQGLAGSPG 885 Query: 698 PGLQFG--GSLGGLGQLQSPGAGVGLPSAASERRPPPPDFATSALGGQPGFPFGAAGRQS 755 P G G GG G PGA G P +A PP P G PG P G G Sbjct: 886 PHGPNGVPGLKGGRGTQGPPGA-TGFPGSAGRVGPPGP-------AGAPG-PAGPLGE-- 934 Query: 756 TPHSGPGVNSPPSAGGGGGSSGGGGGGGAYPPQPDFQPSQRTSASKLGALSLGSFNKPSS 815 PG PP G GS G G G P P P + Sbjct: 935 -----PGKEGPPGLRGDPGSHGRVGDRG--PAGPPGGPGDK------------------- 968 Query: 816 KDNLFGQSCLAALSTACQNMIASLGAPNLNVTFNKKNPPEGKRKLSQNETDGAAVAGNPG 875 G P + PP Q + G PG Sbjct: 969 ------------------------GDPGEDGQPGPDGPPGPAGTTGQR-----GIVGMPG 999 Query: 876 SDYFPGGTAPGAPGPGGPSG----TSSSGSKASGPPNP--PAQGDGTSLSPNYTLESTSG 929 G PG PGP G G T ++G K GPP P P +G P E +G Sbjct: 1000 QRGERG--MPGLPGPAGTPGKVGPTGATGDK--GPPGPVGPPGSNGPVGEPGP--EGPAG 1053 Query: 930 NDGKPVSGGGGRGRGRRKRDSGHVSPGTFFDKYSAAPDSGGAPGVSPGQQQASGAAVGGS 989 NDG P G RG D G P + P S GAPG +PG A G A Sbjct: 1054 NDGTPGRDGAVGERG----DRGDPGP-------AGLPGSQGAPG-TPGPVGAPGDAGQRG 1101 Query: 990 SAGETRGAPTPHEKALTSPSWGKGAELLLGDQPDLIGSLDGGAKSDSSSPNVGEFASDEV 1049 G +RG P +A G L G Q D G + D F + Sbjct: 1102 DPG-SRGPIGPPGRA--------GKRGLPGPQGPRGDKGDHGDRGDRGQKGHRGFTGLQG 1152 Query: 1050 STSYANEDEVSSSSDNPQALVKASRSPLVTGSPKLPPRGVG-AGEHGPKAPPPALGLGIM 1108 + S+ P P+ PP VG +G+ G P +G + Sbjct: 1153 LPGPPGPNGEQGSAGIPGPF-----------GPRGPPGPVGPSGKEGNPGPLGPIGPPGV 1201 Query: 1109 SNSTSTPDSYGGGGGPGHPGTPG 1131 S G G PG PG PG Sbjct: 1202 RGSVGEAGPEGPPGEPGPPGPPG 1224 Score = 85.1 bits (209), Expect = 4e-16 Identities = 176/680 (25%), Positives = 222/680 (32%), Gaps = 116/680 (17%) Query: 579 GHPGDVGQGGLVH--GGPVGGLAQPNFEREGGSTGAGRLGTFEQQAPHLAQESAWFSGPH 636 GHP G GL + GL + + G +G + P Q +GP Sbjct: 177 GHPSHPGPDGLSRPFSAQMAGLDEKSGLGSQVGLMPGSVGPVGPRGPQGLQGQQGGAGPT 236 Query: 637 PPPGDLLPRRMGGSGLPADCGPHDP--SLAPPPPPGGSGVLFRGPLQEPMRMPGEGHVPA 694 PPG+ P D GP P S P PPG G EP R G V Sbjct: 237 GPPGE-----------PGDPGPMGPIGSRGPEGPPGKPG-----EDGEPGRNGNPGEVGF 280 Query: 695 LPSPGLQ-FGGSLG--------GLGQLQSPGAGVGLPSAASERRPPPPDFATSALG--GQ 743 SPG + F G+ G G L+ P VG P + E P P A LG G Sbjct: 281 AGSPGARGFPGAPGLPGLKGHRGHKGLEGPKGEVGAPGSKGEAGPTGPMGAMGPLGPRGM 340 Query: 744 PGF-----PFGAAGRQSTPHSGPGVNSPPSAGGGGGSSGGGGGGGAYPPQPDFQPSQRTS 798 PG P GA G++ H PG P G GSSG G P + Sbjct: 341 PGERGRLGPQGAPGQRGA-HGMPGKPGPMGPLGIPGSSGFPGN-----------PGMKGE 388 Query: 799 ASKLGALSLGSFNKPSSKDNLFGQSCLAALSTACQNMIASLGAPNLNVTFNKKNPPEGKR 858 A GA P G++ +G+P L P K Sbjct: 389 AGPTGARG------PEGPQGQRGET----------GPPGPVGSPGLPGAIGTDGTPGAKG 432 Query: 859 KLSQNETDGA-AVAGNPGSDYFPGGTAP----GAPG-PGGPSGTSSSGSKAS-------G 905 T G AG PGS G T P G PG PG P +G K G Sbjct: 433 PTGSPGTSGPPGSAGPPGSPGPQGSTGPQGIRGQPGDPGVPGFKGEAGPKGEPGPHGIQG 492 Query: 906 PPNPPAQ-------GDGTSLSPNYTL--ESTSGNDGKPVSGG--GGRGRGRRKRDSGHVS 954 P PP + GD ++ P + GN G P S G G +G + G Sbjct: 493 PIGPPGEEGKRGPRGDPGTVGPPGPVGERGAPGNRGFPGSDGLPGPKGAQGERGPVGSSG 552 Query: 955 P-GTFFDKYSAAPDSGGAPGVSPGQQQASGAAVGGSSAGETRGAPTPHEKALTSPSWGKG 1013 P G+ D P G PG+ PG + +G G+ P E P G Sbjct: 553 PKGSQGD-----PGRPGEPGL-PGARGLTGNPGVQGPEGKLGPLGAPGEDGRPGPPGSIG 606 Query: 1014 AELLLGDQPDLIGSLDG--GAKSDSSSPNVGEFASDEVSTSYANED-EVSSSSD-NPQAL 1069 + QP +G L G G+ D P A +D EV S P L Sbjct: 607 ----IRGQPGSMG-LPGPKGSSGDPGKPGEAGNAGVPGQRGAPGKDGEVGPSGPVGPPGL 661 Query: 1070 V--KASRSPL-------VTGSPKLPPRGVGAGEHGPKAPPPALGLGIMSNSTSTPDSYGG 1120 + + P + G P P G G+ G P A+G P G Sbjct: 662 AGERGEQGPPGPTGFQGLPGPPGPPGEGGKPGDQGVPGDPGAVGPLGPRGERGNPGERGE 721 Query: 1121 GGGPGHPGTPGLEQVRTPTSSSGAPPPDEIHPLEILQAQIQLQRQQFSISEDQPLGLKGG 1180 G G PG G+ P G+P P P + +Q + I+ G KG Sbjct: 722 PGITGLPGEKGMAGGHGPDGPKGSPGPSGT-PGDTGPPGLQGMPGERGIAGTP--GPKGD 778 Query: 1181 KKGECAVGASGAQNGDSELG 1200 + G GA G D G Sbjct: 779 RGGIGEKGAEGTAGNDGARG 798 Score = 82.4 bits (202), Expect = 3e-15 Identities = 233/930 (25%), Positives = 288/930 (30%), Gaps = 146/930 (15%) Query: 324 PVGLEPSVGSRHPLMQPPQQAPPPPQQQPPQQPPQQQPPPPPGLLVRQNSCPPALPRPQQ 383 P GL+ G P P + P P + P+ PP PG ++ P P + Sbjct: 223 PQGLQGQQGGAGPTGPPGEPGDPGPMGPIGSRGPEG-PPGKPG----EDGEPGRNGNPGE 277 Query: 384 -GEAGTPSGGLQDGGPMLPSQ-----HAQFEYPIHRLENRSMHPYSEPVFSMQ------- 430 G AG+P G P LP H E P + + P M Sbjct: 278 VGFAGSPGARGFPGAPGLPGLKGHRGHKGLEGPKGEVGAPGSKGEAGPTGPMGAMGPLGP 337 Query: 431 --------HPPPQQAPNQRLQHF--DAPPYMNVAKRPRFD-FPGSAGVDRCASWNGSMHN 479 PQ AP QR H P M P FPG+ G+ A G+ Sbjct: 338 RGMPGERGRLGPQGAPGQRGAHGMPGKPGPMGPLGIPGSSGFPGNPGMKGEAGPTGARGP 397 Query: 480 GALDNHLS------PSAYPGLPGEF----TP----PVPDSFPSGPPLQHPAPDHQSLQQQ 525 P PGLPG TP P SGPP P Q Sbjct: 398 EGPQGQRGETGPPGPVGSPGLPGAIGTDGTPGAKGPTGSPGTSGPPGSAGPPGSPGPQGS 457 Query: 526 QQQQQQQQQQQQQQQQQQQQQQQQQRQNAALMIKQMASRNQQQRLRQPNLAQLGHPGDVG 585 Q + Q + + + + I+ ++ R P G PG VG Sbjct: 458 TGPQGIRGQPGDPGVPGFKGEAGPKGEPGPHGIQGPIGPPGEEGKRGPR----GDPGTVG 513 Query: 586 QGGLVHGGPVGGLAQPNFEREGGSTGA-GRLGTFEQQAPHLAQESAWFSGPHPPPGDL-L 643 G PVG P GS G G G ++ P + G PG+ L Sbjct: 514 PPG-----PVGERGAPGNRGFPGSDGLPGPKGAQGERGPVGSSGPKGSQGDPGRPGEPGL 568 Query: 644 PRRMGGSGLPADCGPHD---PSLAP-----PPPPGGSGVLFRGPLQEPMRMPGEGHVPAL 695 P G +G P GP P AP P PPG G+ RG M +PG Sbjct: 569 PGARGLTGNPGVQGPEGKLGPLGAPGEDGRPGPPGSIGI--RGQ-PGSMGLPGPKGSSGD 625 Query: 696 PS-PGLQFGGSLGGLGQLQSPGAG--------VGLPSAASER--RPPPPDFATSALGGQP 744 P PG G+ G GQ +PG VG P A ER + PP L G P Sbjct: 626 PGKPGE--AGNAGVPGQRGAPGKDGEVGPSGPVGPPGLAGERGEQGPPGPTGFQGLPGPP 683 Query: 745 GFPF--GAAGRQSTP--------------HSGPGVNSPPSAGGGGGSSGGGGGGGAYPPQ 788 G P G G Q P PG P G G G GG G P Sbjct: 684 GPPGEGGKPGDQGVPGDPGAVGPLGPRGERGNPGERGEPGITGLPGEKGMAGGHG--PDG 741 Query: 789 PDFQPSQRTSASKLGALSL-------GSFNKPSSKDNLFGQSCLAALSTA----CQNMIA 837 P P + G L G P K + G A TA + + Sbjct: 742 PKGSPGPSGTPGDTGPPGLQGMPGERGIAGTPGPKGDRGGIGEKGAEGTAGNDGARGLPG 801 Query: 838 SLGAPNLNVTFNKKNPPEGKRKLSQNETDGAAVAGNPGSDYFPGGTAPGAPGPGGPSGTS 897 LG P +K P G R L GNPGS G T GA G GP G Sbjct: 802 PLGPPGPAGPTGEKGEP-GPRGL----VGPPGSRGNPGSRGENGPT--GAVGFAGPQGPD 854 Query: 898 SSGSKASGPPNPPAQGDGTSLSPNYTLESTSGNDGKPVSGGGGRGRGRRKRDSGHVSPGT 957 P P +GD S P S + V G G GRG + PG+ Sbjct: 855 GQPGVKGEPGEPGQKGDAGSPGPQGLAGSPGPHGPNGVPGLKG-GRGTQGPPGATGFPGS 913 Query: 958 FFDKYSAAPDSGGAPGVS-----PGQQQASG--------AAVGGSSAGETRGAP----TP 1000 P GAPG + PG++ G VG G P P Sbjct: 914 A--GRVGPPGPAGAPGPAGPLGEPGKEGPPGLRGDPGSHGRVGDRGPAGPPGGPGDKGDP 971 Query: 1001 HEKALTSPSWGKGAELLLGDQPDLIGSLDGGAKSDSSSPNVGEFASD--EVSTSYANEDE 1058 E P G G Q ++G G + + P + A +V + A D+ Sbjct: 972 GEDGQPGPDGPPGPAGTTG-QRGIVGM--PGQRGERGMPGLPGPAGTPGKVGPTGATGDK 1028 Query: 1059 -----VSSSSDNPQALVKASRSPLVTGSPKLPPRGVGAGEHGPKAPPPALGLGIMSNSTS 1113 V N P G+ P R GE G + P GL + Sbjct: 1029 GPPGPVGPPGSNGPVGEPGPEGP--AGNDGTPGRDGAVGERGDRGDPGPAGLPGSQGAPG 1086 Query: 1114 TPDSYGGGGGPGHPGTPGLEQVRTPTSSSG 1143 TP G G G G PG P +G Sbjct: 1087 TPGPVGAPGDAGQRGDPGSRGPIGPPGRAG 1116 Score = 80.5 bits (197), Expect = 1e-14 Identities = 157/646 (24%), Positives = 199/646 (30%), Gaps = 122/646 (18%) Query: 579 GHPGDVGQGGLVHGGPVGGLAQPNFEREGGSTGA----GRLGTFEQQAPHLAQESAWFSG 634 G PG G G GP G + G G G G + PH Q G Sbjct: 441 GPPGSAGPPG--SPGPQGSTGPQGIRGQPGDPGVPGFKGEAGPKGEPGPHGIQ------G 492 Query: 635 PHPPPGDLLPRRMGGSGLPADCGPHDP--------------SLAPPPPPGGSGVLFRGPL 680 P PPG+ + G G P GP P S P P G G RGP+ Sbjct: 493 PIGPPGE--EGKRGPRGDPGTVGPPGPVGERGAPGNRGFPGSDGLPGPKGAQGE--RGPV 548 Query: 681 QEPMRMPGEGHVPALPSPGLQFGGSLGGLGQLQSPGAGVG-LPSAASERRPPPPDFATSA 739 +G PGL L G +Q P +G L + + RP PP + Sbjct: 549 GSSGPKGSQGDPGRPGEPGLPGARGLTGNPGVQGPEGKLGPLGAPGEDGRPGPP--GSIG 606 Query: 740 LGGQPGF-----PFGAAGRQSTPHSGPGVNSPPSAGGGGGSSGGGGGGGAYPPQPDFQPS 794 + GQPG P G++G P P G G G G PP + Sbjct: 607 IRGQPGSMGLPGPKGSSGDPGKPGEAGNAGVPGQRGAPGKDGEVGPSGPVGPPGLAGERG 666 Query: 795 QRTSASKLGALSLGSFNKPSSKDNLFGQSCLAALSTACQNMIASLGAPNLNVTFNKKNPP 854 ++ G L P + G + A + LG P Sbjct: 667 EQGPPGPTGFQGLPGPPGPPGEGGKPGDQGVPGDPGA----VGPLG-------------P 709 Query: 855 EGKRKLSQNETDGAAVAGNPGSDYFPGGTAPGAP-GPGGPSGTSSSGSKASGPPN----- 908 G+R + E + G PG GG P P G GPSGT +GPP Sbjct: 710 RGERG-NPGERGEPGITGLPGEKGMAGGHGPDGPKGSPGPSGTPGD----TGPPGLQGMP 764 Query: 909 --------PPAQGDGTSLSPNYTLESTSGNDGK--------PVSGGGGRGRGRRKRDSGH 952 P +GD + E T+GNDG P G G G Sbjct: 765 GERGIAGTPGPKGDRGGIGEKGA-EGTAGNDGARGLPGPLGPPGPAGPTGEKGEPGPRGL 823 Query: 953 VSPGTFFDKYSAAPDSGGAPGVSPGQQQASGAAVGGSSAGETRGAP----TPHEKALTSP 1008 V P P S G PG S G+ +GA VG + G P P E Sbjct: 824 VGP----------PGSRGNPG-SRGENGPTGA-VGFAGPQGPDGQPGVKGEPGEPGQKGD 871 Query: 1009 SWGKGAELLLGDQ----PDLIGSLDGGAKSDSSSPNVGEFASDEVSTSYANEDEVSSSS- 1063 + G + L G P+ + L GG + P F + Sbjct: 872 AGSPGPQGLAGSPGPHGPNGVPGLKGG-RGTQGPPGATGFPGSAGRVGPPGPAGAPGPAG 930 Query: 1064 -------DNPQALV--KASRSPLVTGSPKLPPRGVGA-------GEHGPKAPPPALGLGI 1107 + P L S + P PP G G G+ GP PP G Sbjct: 931 PLGEPGKEGPPGLRGDPGSHGRVGDRGPAGPPGGPGDKGDPGEDGQPGPDGPPGPAGTTG 990 Query: 1108 MSNSTSTPDSYGGGGGPGHPGTPGLEQVRTPTSSSG-APPPDEIHP 1152 P G G PG PG G PT ++G PP + P Sbjct: 991 QRGIVGMPGQRGERGMPGLPGPAGTPGKVGPTGATGDKGPPGPVGP 1036 Score = 75.5 bits (184), Expect = 3e-13 Identities = 162/672 (24%), Positives = 213/672 (31%), Gaps = 147/672 (21%) Query: 577 QLGHPGDVGQGGLVHG-----GPVGGLAQPNFEREGGSTGA-GRLGTFEQQAPHLAQESA 630 +LG G GQ G HG GP+G L P G+ G G G + P Q Sbjct: 346 RLGPQGAPGQRG-AHGMPGKPGPMGPLGIPGSSGFPGNPGMKGEAGPTGARGPEGPQGQR 404 Query: 631 WFSGPHPPPGDL-LPRRMGGSGLPADCGPH-DPSLAPPP----PPGGSGVLFRGPLQEPM 684 +GP P G LP +G G P GP P + PP PPG G Q Sbjct: 405 GETGPPGPVGSPGLPGAIGTDGTPGAKGPTGSPGTSGPPGSAGPPGSPGPQGSTGPQGIR 464 Query: 685 RMPGEGHVPALPSPGLQFGGSLGGLGQ-----LQSPGAGVGLPSAASERRP--------P 731 PG+ VP F G G G+ +Q P +G P +R P P Sbjct: 465 GQPGDPGVPG-------FKGEAGPKGEPGPHGIQGP---IGPPGEEGKRGPRGDPGTVGP 514 Query: 732 PPDFATSALGGQPGFPFGAAGRQSTPHSGPGVNSPPSAGGGGGSSGGGGGGGAYPPQPDF 791 P G GFP G+ G P G P + G GS G G G P P Sbjct: 515 PGPVGERGAPGNRGFP-GSDGLPG-PKGAQGERGPVGSSGPKGSQGDPGRPGE-PGLPGA 571 Query: 792 Q-----PSQRTSASKLGALSL-GSFNKPSSKDNLFGQSCLAALSTACQNMIASLGAPNLN 845 + P + KLG L G +P ++ + S+G P Sbjct: 572 RGLTGNPGVQGPEGKLGPLGAPGEDGRPGPPGSI-----------GIRGQPGSMGLPGPK 620 Query: 846 VTFNKKNPPEGKRKLSQNETDGAAVAGN---PGSDYFPGGTAPGAP----------GPGG 892 + P E A V G PG D G + P P GP G Sbjct: 621 GSSGDPGKP--------GEAGNAGVPGQRGAPGKDGEVGPSGPVGPPGLAGERGEQGPPG 672 Query: 893 PSGTSSSGSKASGPPNPPAQGDGTSLSPNYTLESTSGNDGKPVSGGGGRGRGRRKRDSGH 952 P+G GPP PP +G G G P + G RG R Sbjct: 673 PTGFQG----LPGPPGPPGEGGKPG---------DQGVPGDPGAVGPLGPRGERGNPGER 719 Query: 953 VSPGTFFDKYSAAPDSGGAPGVSPGQQQASGAAVGGSSAGETRGAP----TPHEKALTSP 1008 PG + P G G G G+ + G+T G P P E+ + Sbjct: 720 GEPGI-----TGLPGEKGMAG-GHGPDGPKGSPGPSGTPGDT-GPPGLQGMPGERGIAGT 772 Query: 1009 SWGKGAELLLGDQPDLIGSLDGGAKSDSSSPNVGEFASDEVSTSYANEDEVSSSSDNPQA 1068 KG +G++ +G A +D + G + + E P+ Sbjct: 773 PGPKGDRGGIGEK-----GAEGTAGNDGARGLPGPLGPPGPAGPTGEKGE-----PGPRG 822 Query: 1069 LVKASRSPLVTGSPKLPPRGVGAGEHGPKAPPPALGLGIMSNSTSTPDSYGGGGGPGHPG 1128 LV S G+P G G P A+G P G G PG G Sbjct: 823 LVGPPGS---RGNP---------GSRGENGPTGAVGFAGPQGPDGQPGVKGEPGEPGQKG 870 Query: 1129 TPGLEQVRTPTSSSGAPPPDEIHPLEILQAQIQLQRQQFSISEDQPLGLKGGKKGECAVG 1188 G P +G+P P + + GLKGG+ + G Sbjct: 871 DAGSP---GPQGLAGSPGPHGPNGVP---------------------GLKGGRGTQGPPG 906 Query: 1189 ASGAQNGDSELG 1200 A+G +G Sbjct: 907 ATGFPGSAGRVG 918 Score = 61.2 bits (147), Expect = 6e-09 Identities = 145/566 (25%), Positives = 178/566 (31%), Gaps = 144/566 (25%) Query: 607 GGSTGAGRLGTFEQQAPHLAQESAWFSG---PHPPPGDLLPR-RMGGSGLPADCGPHDPS 662 GG+T GR ++ P L G P PPG PR G G P GP Sbjct: 102 GGNTNFGRGRKGQKGEPGLVPVVTGIRGRPGPAGPPGSQGPRGERGPKGRPGPRGPQGID 161 Query: 663 LAPPPPPGGSGVLFRGPLQEPMRMPGEGHVPALPSP-GLQ--FGGSLGGLGQLQSPGAGV 719 P PG G PG P+ P P GL F + GL + G+ V Sbjct: 162 -GEPGVPGQPGA------------PGPPGHPSHPGPDGLSRPFSAQMAGLDEKSGLGSQV 208 Query: 720 GL-PSAASERRPPPPDFATSALGGQPGFPFGAAGRQSTPHSGPGVNSPPSAGGGGGSSGG 778 GL P + P P L GQ G G G PP G G G Sbjct: 209 GLMPGSVGPVGPRGPQ----GLQGQQG--------------GAGPTGPPGEPGDPGPMGP 250 Query: 779 GGGGGAYPPQPDFQPSQRTSASKLGALSLGSFNKPSSKDNLFGQSCLAALSTACQNMIAS 838 G G P P +P G +P N G+ A S + + Sbjct: 251 IGSRG--PEGPPGKP--------------GEDGEPGRNGNP-GEVGFAG-SPGARGFPGA 292 Query: 839 LGAPNLNVTFNKKN--PPEGKRKLSQNETDGAAVAGNPGSDYFPGGTAP-GAPGPGGPSG 895 G P L K P+G+ G PGS G T P GA GP GP G Sbjct: 293 PGLPGLKGHRGHKGLEGPKGE-------------VGAPGSKGEAGPTGPMGAMGPLGPRG 339 Query: 896 TSSSGSKASGPPNPPAQGDGTSLSPNYTLESTSGNDGKPVSGGGGRGRGRRKRDSGHVSP 955 + GP P Q G GKP G + P Sbjct: 340 MPGERGRL-GPQGAPGQ------------RGAHGMPGKP----------------GPMGP 370 Query: 956 GTFFDKYSAAPDSGGAPGVSPGQQQASGAAVGGSSAGETRGAPTPH-EKALTSPSWGKGA 1014 P S G PG +PG + +G RG P ++ T P G+ Sbjct: 371 -------LGIPGSSGFPG-NPGMKGEAGPT-------GARGPEGPQGQRGETGPPGPVGS 415 Query: 1015 ELLLGDQPDLIGSLDG--GAKSDSSSPNVGEFASDEVSTSYANEDEVSSSSDNPQALVKA 1072 L P IG+ DG GAK + SP S ++ S PQ + Sbjct: 416 PGL----PGAIGT-DGTPGAKGPTGSPGT----SGPPGSAGPPGSPGPQGSTGPQGIRGQ 466 Query: 1073 SRSPLVTG-----SPKLPPRGVGA----------GEHGPKAPPPALGLGIMSNSTSTPDS 1117 P V G PK P G G+ GP+ P +G P + Sbjct: 467 PGDPGVPGFKGEAGPKGEPGPHGIQGPIGPPGEEGKRGPRGDPGTVGPPGPVGERGAPGN 526 Query: 1118 YGGGGGPGHPGTPGLEQVRTPTSSSG 1143 G G G PG G + R P SSG Sbjct: 527 RGFPGSDGLPGPKGAQGERGPVGSSG 552 Score = 50.1 bits (118), Expect = 1e-05 Identities = 76/236 (32%), Positives = 90/236 (38%), Gaps = 47/236 (19%) Query: 579 GHPGDVGQGGLVHGGPVGGLAQPNFEREGGSTGA-GRLGTFEQQAPHLAQESAWFSGPHP 637 G PG VG G GPVG +P E G+ G GR G ++ A G Sbjct: 1029 GPPGPVGPPG--SNGPVG---EPGPEGPAGNDGTPGRDGAVGERGDRGDPGPAGLPGSQG 1083 Query: 638 PPGDLLPRRMGGSGLPADCGPH-DP-SLAPPPPPGGSGVLFRGPLQEPMRMPGEGHVPAL 695 PG G G P D G DP S P PPG +G RG +PG P Sbjct: 1084 APGT-----PGPVGAPGDAGQRGDPGSRGPIGPPGRAGK--RG-------LPG----PQG 1125 Query: 696 PSPGLQFGGSLGGLGQLQSPG-AGV-GLPSAASERRPPPPDFATSALG--------GQPG 745 P G G GQ G G+ GLP PP P+ + G G PG Sbjct: 1126 PRGDKGDHGDRGDRGQKGHRGFTGLQGLPG------PPGPNGEQGSAGIPGPFGPRGPPG 1179 Query: 746 FPFGAAGRQSTPHSGP-GVNSPPSAGGGGGSSG-GGGGGGAYPPQPDFQPSQRTSA 799 P G +G++ P GP G PP G G +G G G PP P P T+A Sbjct: 1180 -PVGPSGKEGNP--GPLGPIGPPGVRGSVGEAGPEGPPGEPGPPGPPGPPGHLTAA 1232 Score = 43.1 bits (100), Expect = 0.002 Identities = 38/132 (28%), Positives = 51/132 (38%), Gaps = 11/132 (8%) Query: 1076 PLVTG-----SPKLPPRGVGA-GEHGPKAPPPALGLGIMSNSTSTPDSYGGGGGPGHPGT 1129 P+VTG P PP G GE GPK P G + P G G PGHP Sbjct: 122 PVVTGIRGRPGPAGPPGSQGPRGERGPKGRPGPRGPQGIDGEPGVPGQPGAPGPPGHPSH 181 Query: 1130 PGLEQVRTPTSSSGAPPPDEIHPLEILQAQIQLQRQQFS-ISEDQPLGLKGGKKGECAVG 1188 PG + + P S+ A ++ L +Q+ L + P GL+G + G G Sbjct: 182 PGPDGLSRPFSAQMAGLDEK----SGLGSQVGLMPGSVGPVGPRGPQGLQGQQGGAGPTG 237 Query: 1189 ASGAQNGDSELG 1200 G +G Sbjct: 238 PPGEPGDPGPMG 249 >gi|116256356 alpha 4 type IV collagen precursor [Homo sapiens] Length = 1690 Score = 93.2 bits (230), Expect = 1e-18 Identities = 294/1198 (24%), Positives = 372/1198 (31%), Gaps = 216/1198 (18%) Query: 42 GGPPGPVDPAMSALGEPPILGMNMEPYGFHARGHSELHAGGLQAQPVHGFFGGQQPHHGH 101 GGP GP GEP ++G +P +G+ + G P G+ G Sbjct: 204 GGPAGPTGYP----GEPGLVGPPGQPGRPGLKGNPGVGVKGQMGDP------GEVGQQGS 253 Query: 102 PGSH---HPHQHHPHFG--------GNFGGPDP-------GASCLHGGRLLGYGGAAGGL 143 PG P + G G G P P G + G+ G G Sbjct: 254 PGPTLLVEPPDFCLYKGEKGIKGIPGMVGLPGPPGRKGESGIGAKGEKGIPGFPGPRGDP 313 Query: 144 GS--QPPFAEGYEHMAESQGPESFGPQRPGNLPDFHSSGASSHAVPAPCLPLDQSPNRAA 201 GS P F + P FG P P + P LPL P Sbjct: 314 GSYGSPGFPGLKGELGLVGDPGLFGLIGPKGDPGNRGHPGPPGVLVTPPLPLKGPPGDP- 372 Query: 202 SFHGLPSSSGSDSHSLEPRRVTNQGAVDSLEYNYPGEAPSGHFDMFSPSDSEGQLPHYAA 261 G P G P G PGEA +G P G LP Sbjct: 373 ---GFPGRYGETGDVGPPGPPGLLGR--------PGEACAGMIGPPGPQGFPG-LPGLPG 420 Query: 262 GRQVPG--GAFPGASAMPRAAGMVGLSKMHAQPPQQQPQQQQQPQQQQQQHGVFFERFSG 319 +PG + PG P + G+ G + P G S Sbjct: 421 EAGIPGRPDSAPGKPGKPGSPGLPGAPGLQGLP------------------GSSVIYCSV 462 Query: 320 ARKMPVGLEPSVGSRHPLMQPPQQAPPPPQQQPPQ----QPPQQQPPPPPGLLVRQNSCP 375 P G++ VG PP P ++ +P PP PPGL RQ S Sbjct: 463 GNPGPQGIKGKVG-------PPGGRGPKGEKGNEGLCACEPGPMGPPGPPGLPGRQGSKG 515 Query: 376 PALPRPQQGEAGTPSGGLQDGGPMLPSQHAQFEYPIHRLENRSMHPYSEPVFSMQHPPPQ 435 G G P +G P LP +H P ++ M V ++ + Sbjct: 516 DLGLPGWLGTKGDPGPPGAEGPPGLPGKHGASGPPGNKGAKGDM-----VVSRVKGHKGE 570 Query: 436 QAPNQRLQHFDAPPYMNVAKRPRFDFPGSAGVDRCASWNGSMHNGALDNHLSPSAYPGLP 495 + P D PP PGS G D A G +P G P Sbjct: 571 RGP-------DGPPGFPGQ-------PGSHGRDGHAGEKGDPGPPGDHEDATPGG-KGFP 615 Query: 496 GEFTPPVPDSFPSGPP-LQHPAPD----HQSLQQQQQQQQQQQQQQQQQQQQQQQQQQQQ 550 G PP + P GPP L P P H + + + Q+ Sbjct: 616 GPLGPP-GKAGPVGPPGLGFPGPPGERGHPGVPGHPGVRGPDGLKGQKGDTISCNVTYPG 674 Query: 551 RQNAALMIKQMASRNQQQRLRQPNLAQLGHPGDVGQGGLVHGGPVGGLAQPNFEREGGST 610 R + P L+ G G G+ G + G P F + G Sbjct: 675 RHGPPGFDGPPGPKGFPGPQGAPGLS--GSDGHKGRPGTPGTAEIPG--PPGFRGDMGDP 730 Query: 611 GAGRLGTFEQQAPHLAQESAWFSGPHPPPGDLLPRRMGGSGLPADCGPHDPSLAPPPPPG 670 G G ++ + GP PPG P G G+P D P L PP G Sbjct: 731 GFG------------GEKGSSPVGPPGPPGS--PGVNGQKGIPGD--PAFGHLGPPGKRG 774 Query: 671 GSGVL-FRGPLQEPMRMPGEGHVPALPSPGLQFGGSLGGLGQLQSPGAGVGLPSAASERR 729 SGV +GP +P EG PA L G G G PG G P + ER Sbjct: 775 LSGVPGIKGPRGDPGCPGAEG--PAGIPGFLGLKGPKGREGHAGFPGVP-GPPGHSCERG 831 Query: 730 PPPPDFATSALGGQPGFPFGAAGRQSTP--HSGPGVNSPPSAGGGGGSSGGGGGGGAYPP 787 P + GQPG P G G P PG PP G G G G GA+ P Sbjct: 832 AP-------GIPGQPGLP-GYPGSPGAPGGKGQPGDVGPPGPAGMKGLPGLPGRPGAHGP 883 Query: 788 Q----------PDFQPSQRTSASKLGALSLGSFNKPSSKDNLFGQSCLAALSTACQNMIA 837 D P G F P + + C A + ++ Sbjct: 884 PGLPGIPGPFGDDGLPGPPGPKGPRGLPGFPGF--PGERGKPGAEGCPGAKGEPGEKGMS 941 Query: 838 SL-GAPNLNVTFNKKNPP--EGKRKL-SQNETDGAAVAGNPGSDYFPG-----GTAP--- 885 L G L PP EG+ + SQ T G G PG D FPG GT Sbjct: 942 GLPGDRGLRGAKGAIGPPGDEGEMAIISQKGTPGEP--GPPGDDGFPGERGDKGTPGMQG 999 Query: 886 --GAPGPGGPSG--TSSSGSKAS-GPPNPPAQGDGTSLSPNYTLESTSGNDGKPVSGG-- 938 G PG GP G G K GPP PP T L G+ G+P S G Sbjct: 1000 RRGEPGRYGPPGFHRGEPGEKGQPGPPGPPGPPGSTGLRGFIGFPGLPGDQGEPGSPGPP 1059 Query: 939 ------GGRG-RGRRKRDSGHVSPGTFFDKYSAAPDSGGAPGVS--PGQQQASGAAVGGS 989 G RG +G + + H P P G PG PG ASG G Sbjct: 1060 GFSGIDGARGPKGNKGDPASHFGP----------PGPKGEPGSPGCPGHFGASGEQ-GLP 1108 Query: 990 SAGETRGAP-TPHEKALTSPSWGKGAELLLG--DQPDLIGS-----LDG--------GAK 1033 RG+P P + P G + G QP +G L G G K Sbjct: 1109 GIQGPRGSPGRPGPPGSSGPPGCPGDHGMPGLRGQPGEMGDPGPRGLQGDPGIPGPPGIK 1168 Query: 1034 SDSSSPNVGEF---ASDEVSTSYANEDEVSSSSDNPQALVKASRSPLVTGSPKLPPRGVG 1090 S SP + + + + +V +K R GSP + P G Sbjct: 1169 GPSGSPGLNGLHGLKGQKGTKGASGLHDVGPPGPVGIPGLKGERGD--PGSPGISPPGP- 1225 Query: 1091 AGEHGPKAPPPALGLGIMSNSTS-TPDSYGGGGGPGHPGTPGLEQVRTPTSSSGAPPP 1147 G+ GP PP + G + +T P G PG G PG P GAP P Sbjct: 1226 RGKKGPPGPPGSSGPPGPAGATGRAPKDIPDPGPPGDQGPPG------PDGPRGAPGP 1277 Score = 80.1 bits (196), Expect = 1e-14 Identities = 290/1213 (23%), Positives = 380/1213 (31%), Gaps = 198/1213 (16%) Query: 43 GPPGPVDPAMSALGEPPILGMNMEPYGFHARGHSELHAGGLQAQP--VHGFFGGQQPHHG 100 GPPGP P + LG P +G++ E RG P V GF G G Sbjct: 68 GPPGPQGP-IGPLGAPGPIGLSGEKGMRGDRGPPGAAGDKGDKGPTGVPGF-PGLDGIPG 125 Query: 101 HPGSHHPHQHHPHFGGNFGGPDPGASCLHGGR-LLGYGGAAGGLGSQPPFAEGYEHMAES 159 HPG P G N DPG GGR LG GG G G + + Sbjct: 126 HPGPPGPRGKPGMSGHNGSRGDPG---FPGGRGALGPGGPLGHPGEKGEKGNSVFILGAV 182 Query: 160 QGPESFGPQRPGNLPDFHSS-GASSHAVPAPCLPLDQSPNRAASFHGLPSSSGSDSHSLE 218 +G + G + LP S GA A P + G P G Sbjct: 183 KGIQ--GDRGDPGLPGLPGSWGAGGPAGPT-------------GYPGEPGLVGPPGQPGR 227 Query: 219 PRRVTNQGAVDSLEYNYPGEAPS----GHFDMFSPSDSEGQLPHYAAGRQVPGGAFPGAS 274 P N G + PGE G + P D Y + + G PG Sbjct: 228 PGLKGNPGVGVKGQMGDPGEVGQQGSPGPTLLVEPPD----FCLYKGEKGIKG--IPGMV 281 Query: 275 AMPRAAGMVGLSKMHAQPPQQQPQQQQQPQQQQQQHGVFFERFSGARKMP--------VG 326 +P G G S + A+ + P F G + +G Sbjct: 282 GLPGPPGRKGESGIGAKGEKGIPGFPGPRGDPGSYGSPGFPGLKGELGLVGDPGLFGLIG 341 Query: 327 LEPSVGSR-HPLMQPPQQAPPPPQQQPPQQPP---------QQQPPPPPGLLVRQNSCPP 376 + G+R HP PP P + PP P PP PPGLL R Sbjct: 342 PKGDPGNRGHPGPPGVLVTPPLPLKGPPGDPGFPGRYGETGDVGPPGPPGLLGRPGEACA 401 Query: 377 AL---PRPQ--------QGEAGTPSGGLQDGGPMLPSQHAQFEYP----IHRLENRSM-- 419 + P PQ GEAG P G D P P + P + L S+ Sbjct: 402 GMIGPPGPQGFPGLPGLPGEAGIP--GRPDSAPGKPGKPGSPGLPGAPGLQGLPGSSVIY 459 Query: 420 ----HPYSEPVFSMQHPPPQQAP-----NQRLQHFDAPPYMNVAKRPRFDFPGSAGVDRC 470 +P + + PP + P N+ L + P G G Sbjct: 460 CSVGNPGPQGIKGKVGPPGGRGPKGEKGNEGLCACEPGPM------------GPPGPPGL 507 Query: 471 ASWNGSMHNGALDNHLSPSAYPGLPGEFTPP-VPDSF-PSGPPLQHPAPDHQSLQQQQQQ 528 GS + L L PG PG PP +P SGPP A + + + Sbjct: 508 PGRQGSKGDLGLPGWLGTKGDPGPPGAEGPPGLPGKHGASGPPGNKGAKGDMVVSRVKGH 567 Query: 529 QQQQQQQQQ-----QQQQQQQQQQQQQRQNAALMIKQMASRNQQQRLRQPNLAQLGHPGD 583 + ++ Q + ++ + + + P L G G Sbjct: 568 KGERGPDGPPGFPGQPGSHGRDGHAGEKGDPGPPGDHEDATPGGKGFPGP-LGPPGKAGP 626 Query: 584 VGQGGLVHGGPVGGLAQPNFEREGGSTGAGRLGTFEQQAPHLAQESAWFSGPHPPPG--- 640 VG GL GP G P G G L + Q + + G H PPG Sbjct: 627 VGPPGLGFPGPPGERGHPGVPGHPGVRGPDGL---KGQKGDTISCNVTYPGRHGPPGFDG 683 Query: 641 ----DLLPRRMGGSGLPADCG----PHDPSLAPPPPPGGSGVLFRGPLQEPMRMPGEGHV 692 P G GL G P P A P P G FRG + +P +G Sbjct: 684 PPGPKGFPGPQGAPGLSGSDGHKGRPGTPGTAEIPGPPG----FRGDMGDPGFGGEKGSS 739 Query: 693 PALP-----SPGLQFGGSLGG---LGQLQSPGAG--VGLPSAASERRPPPPDFATSALGG 742 P P SPG+ + G G L PG G+P R P A G Sbjct: 740 PVGPPGPPGSPGVNGQKGIPGDPAFGHLGPPGKRGLSGVPGIKGPRGDPGCPGAEGP-AG 798 Query: 743 QPGFPF--GAAGRQSTPHSG-PGVNSPPSAGGGGGSSGGGGGGG--AYPPQPDFQPSQRT 797 PGF G GR+ H+G PGV PP G+ G G G YP P P + Sbjct: 799 IPGFLGLKGPKGREG--HAGFPGVPGPPGHSCERGAPGIPGQPGLPGYPGSPG-APGGKG 855 Query: 798 SASKLGALSLGSFNKPSSKDNLFGQSCLAALSTACQNMIASLGAPNLNVTFNKKN----- 852 +G P + G L A G P + F Sbjct: 856 QPGDVG---------PPGPAGMKGLPGLPGRPGAH----GPPGLPGIPGPFGDDGLPGPP 902 Query: 853 PPEGKRKLSQNETDGAAVAGNPGSDYFPGGTAPGAPGPGGPSGTSSS----GSK-ASGPP 907 P+G R L G PG++ PG A G PG G SG G+K A GPP Sbjct: 903 GPKGPRGLP-GFPGFPGERGKPGAEGCPG--AKGEPGEKGMSGLPGDRGLRGAKGAIGPP 959 Query: 908 NPPAQGDGTSLSPNYTLESTSGNDGKPVSGG--GGRGRGRRKRDSGHVSPGTFFDKYSAA 965 + S G+DG P G G G R+ + G P F Sbjct: 960 GDEGEMAIISQKGTPGEPGPPGDDGFPGERGDKGTPGMQGRRGEPGRYGPPGFHRGEPGE 1019 Query: 966 PDSGGAPGVSPGQQQASGAA--VGGSSAGETRGAP-TPHEKALTSPSWGKGAELLLGDQP 1022 G PG PG ++G +G +G P +P + +G + GD Sbjct: 1020 KGQPGPPG-PPGPPGSTGLRGFIGFPGLPGDQGEPGSPGPPGFSGIDGARGPKGNKGDPA 1078 Query: 1023 DLIGSLDGGAKSDSSSPNV-GEFASDEVSTSYANEDEVSSSSDNPQALVKASRSPLVTGS 1081 G G K + SP G F + Q L P + G Sbjct: 1079 SHFGP--PGPKGEPGSPGCPGHFGAS-----------------GEQGL------PGIQGP 1113 Query: 1082 PKLPPRGVGAGEHGPKAPPPALGLGIMSNSTSTPDSYGGGGGPGHPGTPGLEQVRTPTSS 1141 P R G GP P G+ + G G G PG PG ++ P Sbjct: 1114 RGSPGRPGPPGSSGPPGCPGDHGMPGLRGQPGEMGDPGPRGLQGDPGIPGPPGIKGP--- 1170 Query: 1142 SGAPPPDEIHPLE 1154 SG+P + +H L+ Sbjct: 1171 SGSPGLNGLHGLK 1183 Score = 71.6 bits (174), Expect = 5e-12 Identities = 294/1222 (24%), Positives = 377/1222 (30%), Gaps = 278/1222 (22%) Query: 43 GPPGPVD-PAMSAL-GEPPILGMNMEPYGFHARGHSELHAG--GLQAQP----VHGFFGG 94 GPPGP P + L GE I G G + S G GLQ P ++ G Sbjct: 405 GPPGPQGFPGLPGLPGEAGIPGRPDSAPGKPGKPGSPGLPGAPGLQGLPGSSVIYCSVGN 464 Query: 95 QQPHH-----GHPGSHHPHQHHPHFG------GNFGGPDP-GASCLHGGRLLGYGGAAGG 142 P G PG P + G G G P P G G + G G G Sbjct: 465 PGPQGIKGKVGPPGGRGPKGEKGNEGLCACEPGPMGPPGPPGLPGRQGSK--GDLGLPGW 522 Query: 143 LGSQ----PPFAEGYEHMAESQGPESFGPQRPGNLPDFHSSGASSHAVPAPCLPLDQSPN 198 LG++ PP AEG + G S P G D S H ++ P+ Sbjct: 523 LGTKGDPGPPGAEGPPGLPGKHGA-SGPPGNKGAKGDMVVSRVKGHKG-------ERGPD 574 Query: 199 RAASFHGLPSSSGSDSHSLEPRRVT-----------------------NQGAVDSLEYNY 235 F G P S G D H+ E G V + Sbjct: 575 GPPGFPGQPGSHGRDGHAGEKGDPGPPGDHEDATPGGKGFPGPLGPPGKAGPVGPPGLGF 634 Query: 236 PGEAPS-------GHFDMFSPSDSEGQLPHYAA------GRQVPGG--AFPGASAMPRAA 280 PG GH + P +GQ + GR P G PG P Sbjct: 635 PGPPGERGHPGVPGHPGVRGPDGLKGQKGDTISCNVTYPGRHGPPGFDGPPGPKGFPGPQ 694 Query: 281 GMVGLSKMHAQPPQQ-QPQQQQQPQQQQQQHGVFFERFSGAR-KMPVGL-----EPSVGS 333 G GLS + P + P + + F G + PVG P V Sbjct: 695 GAPGLSGSDGHKGRPGTPGTAEIPGPPGFRGDMGDPGFGGEKGSSPVGPPGPPGSPGVNG 754 Query: 334 RHPLMQPPQ--QAPPPPQQQPPQQPPQQQPPPPPGLLVRQNSCPPALPRPQQGEAGTPSG 391 + + P PP ++ P + P PG CP A +G AG P G Sbjct: 755 QKGIPGDPAFGHLGPPGKRGLSGVPGIKGPRGDPG-------CPGA-----EGPAGIP-G 801 Query: 392 GLQDGGPMLPSQHAQFEY----PIHRLENRSMHPYSEPVFSMQHPPPQQAPNQRLQHFDA 447 L GP HA F P H E + +P +P AP + Q D Sbjct: 802 FLGLKGPKGREGHAGFPGVPGPPGHSCERGAPGIPGQPGLP-GYPGSPGAPGGKGQPGDV 860 Query: 448 PPYMNVAKRPRFDFPGSAGVDRCASWNGSMHNGALDNHLSPSAYPGLPGEFTPP-VPDSF 506 P PG AG+ G GA P PG+PG F +P Sbjct: 861 GP------------PGPAGMKGLPGLPG--RPGAH----GPPGLPGIPGPFGDDGLPG-- 900 Query: 507 PSGPPLQHPAPDHQSLQQQQQQQQQQQQQQQQQQQQQQQQQQQQRQNAALMIKQMASRNQ 566 P GP P ++ + + + + + K M+ Sbjct: 901 PPGPKGPRGLPGFPGFPGERGKPGAEGCPGAKGEPGE---------------KGMSGLPG 945 Query: 567 QQRLRQPNLAQLGHPGDVGQGGLV-------HGGPVGGLAQPNFEREGGSTGA-GRLGTF 618 + LR A +G PGD G+ ++ GP G P + G+ G GR G Sbjct: 946 DRGLRGAKGA-IGPPGDEGEMAIISQKGTPGEPGPPGDDGFPGERGDKGTPGMQGRRGE- 1003 Query: 619 EQQAPHLAQESAWFSGPHPPPGDLLPRRMGGSGLPADCGPHDPSLAPPPPPGGSGVLFRG 678 G + PPG G P + G P PP PPG +G+ RG Sbjct: 1004 --------------PGRYGPPGF-------HRGEPGEKGQPGPP-GPPGPPGSTGL--RG 1039 Query: 679 PLQEPMRMPGEGHVPALPSPGLQFGGSLGGLGQLQSPGAGVGLPSAASERRPPPPDFATS 738 + P +PG+ P P P G+ + P G P AS PP P Sbjct: 1040 FIGFP-GLPGDQGEPGSPGPP-----GFSGIDGARGPKGNKGDP--ASHFGPPGPK---- 1087 Query: 739 ALGGQPGFP-----FGAAGRQSTP-----HSGPGVNSPPSAGGGGGSSGGGGGGGAY-PP 787 G+PG P FGA+G Q P PG PP + G G G G G P Sbjct: 1088 ---GEPGSPGCPGHFGASGEQGLPGIQGPRGSPGRPGPPGSSGPPGCPGDHGMPGLRGQP 1144 Query: 788 QPDFQPSQRTSASKLGALSLGSFNKPSSKDNLFGQSCLAALS-TACQNMIASLGAPNLNV 846 P R G PS L G L T + + +G P Sbjct: 1145 GEMGDPGPRGLQGDPGIPGPPGIKGPSGSPGLNGLHGLKGQKGTKGASGLHDVGPPG--- 1201 Query: 847 TFNKKNPPEGKRKLSQNETDGAAVAGNPGSDYFPGGTAPGAPGPGGPSGTSSSGSKASGP 906 P K + + G + G G PG PG+ GP GP+G + K Sbjct: 1202 ---PVGIPGLKGERGDPGSPGISPPGPRGKKGPPG--PPGSSGPPGPAGATGRAPKDIPD 1256 Query: 907 PNPPAQGDGTSLSPNYTLESTSGNDGKPVSGGGGRGRGRRKRDSGHVSPGTFFDKYSAAP 966 P PP GD P + G G P G D G P P Sbjct: 1257 PGPP--GDQGPPGP----DGPRGAPGPPGLPGSVDLLRGEPGDCGLPGP-------PGPP 1303 Query: 967 DSGGAPGVS--PGQQQASG--AAVGGSSAGETRGAP-TPHEKALTSPSWGKGAELLLGDQ 1021 G PG PG G VG G P P EK L P KG L Sbjct: 1304 GPPGPPGYKGFPGCDGKDGQKGPVGFPGPQGPHGFPGPPGEKGLPGPPGRKGPTGL---- 1359 Query: 1022 PDLIGSLDGGAKSDSSSPNVGEFASDEVSTSYANEDEVSSSSDNPQALVKASRSPLVTGS 1081 G + + P A+ D+ R P + G+ Sbjct: 1360 --------PGPRGEPGPP--------------ADVDD-------------CPRIPGLPGA 1384 Query: 1082 PKL--PPRGVG-AGEHGPKAP----PPAL----GLGIMSNSTSTPDSYGGGGGPGHPGTP 1130 P + P +G G GP P P L G+ + S P G G G+PG P Sbjct: 1385 PGMRGPEGAMGLPGMRGPSGPGCKGEPGLDGRRGVDGVPGSPGPPGRKGDTGEDGYPGGP 1444 Query: 1131 GLEQVRTPTSSSGAPPPDEIHP 1152 G P G P P P Sbjct: 1445 G------PPGPIGDPGPKGFGP 1460 Score = 55.8 bits (133), Expect = 3e-07 Identities = 127/516 (24%), Positives = 157/516 (30%), Gaps = 160/516 (31%) Query: 656 CGPHDPSLAPPPPPGGSGVLFRGPLQEPMRMPGEGHVPALPSPGLQFGGSLGGLGQLQSP 715 C P S PP PPG G + GPL P G +G G+ Sbjct: 57 CVPEKGSRGPPGPPGPQGPI--GPLGAP--------------------GPIGLSGEKGMR 94 Query: 716 GAGVGLPSAASERRPPPPDFATSALGGQPGFPFGAAGRQSTPHSGPGVNSPPSAGGGGGS 775 G G P AA ++ P G PGFP G G PG PP G G Sbjct: 95 G-DRGPPGAAGDKGDKGPT-------GVPGFP-GLDGI-------PGHPGPPGPRGKPGM 138 Query: 776 SGGGGGGGAYPPQPDFQPSQRTSASKLGALSLGS-FNKPSSKDNLFGQSCLAALSTACQN 834 SG G G P F P R GAL G P K N Sbjct: 139 SGHNGSRG----DPGF-PGGR------GALGPGGPLGHPGEKGEK-------------GN 174 Query: 835 MIASLGAPNLNVTFNKKNPPEGKRKLSQNETDGAAVAGNPGSDYFPGGTAPGAPGPGGPS 894 + LGA + G+ G PG PG+ G GGP+ Sbjct: 175 SVFILGAVK-------------------------GIQGDRGDPGLPG--LPGSWGAGGPA 207 Query: 895 GTSSSGSKAS--GPPNPPAQGDGTSLSPNYTLESTSGNDGKPVSGGGGRGRGRRKRDSGH 952 G + + GPP P + G +P ++ G+ G+ V G G + Sbjct: 208 GPTGYPGEPGLVGPPGQPGR-PGLKGNPGVGVKGQMGDPGE-VGQQGSPG------PTLL 259 Query: 953 VSPGTFFDKYSAAPDSGGAPGV-----SPGQQQASGAAVGGSSAGETRGAPTPHEKALTS 1007 V P F Y G PG+ PG++ SG G P + S Sbjct: 260 VEPPDFC-LYKGEKGIKGIPGMVGLPGPPGRKGESGIGAKGEKGIPGFPGPRGDPGSYGS 318 Query: 1008 PSW-GKGAELLLGDQPDLIGSLDGGAKSDSSSPNVGEFASDEVSTSYANEDEVSSSSDNP 1066 P + G EL L P L G + G K D + P Sbjct: 319 PGFPGLKGELGLVGDPGLFGLI--GPKGDPG----------------------NRGHPGP 354 Query: 1067 QALVKASRSPL--VTGSPKLPPRGVGAGEHGPKAPPPALG-------------------- 1104 ++ PL G P P R G+ GP PP LG Sbjct: 355 PGVLVTPPLPLKGPPGDPGFPGRYGETGDVGPPGPPGLLGRPGEACAGMIGPPGPQGFPG 414 Query: 1105 -------LGIMSNSTSTPDSYGGGGGPGHPGTPGLE 1133 GI S P G G PG PG PGL+ Sbjct: 415 LPGLPGEAGIPGRPDSAPGKPGKPGSPGLPGAPGLQ 450 Score = 33.9 bits (76), Expect = 1.1 Identities = 29/111 (26%), Positives = 43/111 (38%), Gaps = 12/111 (10%) Query: 1092 GEHGPKAPPPALGLGIMSNSTSTPDSYGGGGGPGHPGTPGLEQVRTPTSSSGAPPPDEIH 1151 G+ G P + G G + T P G G PG PG PGL+ P E+ Sbjct: 190 GDPGLPGLPGSWGAGGPAGPTGYPGEPGLVGPPGQPGRPGLKGNPGVGVKGQMGDPGEVG 249 Query: 1152 PLEILQAQIQLQRQQFSISEDQPLGLKG-----------GKKGECAVGASG 1191 + ++ F + + + G+KG G+KGE +GA G Sbjct: 250 QQGSPGPTLLVEPPDFCLYKGEK-GIKGIPGMVGLPGPPGRKGESGIGAKG 299 >gi|40068464 AT rich interactive domain 1B (SWI1-like) isoform 2 [Homo sapiens] Length = 2191 Score = 93.2 bits (230), Expect = 1e-18 Identities = 130/486 (26%), Positives = 165/486 (33%), Gaps = 84/486 (17%) Query: 514 HPAPDHQSLQQQQQQQQQQQQQQQQQQQQQQQQQQQQRQNAALMIKQMASRNQQQRLRQP 573 H H +LQQQ Q QQQQQQQQQQQQQQQQQQ N +L Sbjct: 40 HHLHHHHALQQQLNQFQQQQQQQQQQQQQQQQQQHPISNNNSL----------------- 82 Query: 574 NLAQLGHPGDVGQGGLVHGGPVGGLAQPNFERE----GGSTGAGRLGTFEQQAPHLAQES 629 GG GG QP + E GG+ + G + P L + Sbjct: 83 ------------------GGAGGGAPQPGPDMEQPQHGGAKDSAAGGQADPPGPPLLSKP 124 Query: 630 AWFSGPHPPPGDLLPRRMGGSGLPADCGPHDPSLAPPPPPGGSGVLFRGPLQEPMRMPGE 689 P G+ R GL A G P P PGG G GP P Sbjct: 125 GDEDDAPPKMGEPAGGRYEHPGLGA-LGTQQP---PVAVPGGGG----GPAAVPEFNNYY 176 Query: 690 GH-VPALPSPGLQFGGSLGGLGQLQSPGAG-VGLPSAASERRPPPPDFATSALGGQPGFP 747 G PA PG + G G QSPG G + SAA+ P D ++ G P Sbjct: 177 GSAAPASGGPGGRAGPCFDQHGGQQSPGMGMMHSASAAAAGAPGSMDPLQNSHEGYPNSQ 236 Query: 748 FGAAGRQSTPHSGPGVNSPPSAGGGGGSSGGGGGGGAYPPQPDFQPSQRTSASKLGALSL 807 S P +G G GGGGGS GGGGGGGA +A+ A Sbjct: 237 CNHYPGYSRPGAGGGGGG--GGGGGGGSGGGGGGGGAGAGGAGAGAVAAAAAAAAAAAGG 294 Query: 808 GSFNKPSSKDNLFGQSCLAALSTACQNMIASLGAPNLNVTFNKKNPPEGKRKLSQNETDG 867 G +G L +P P G G Sbjct: 295 GGGGGYGGSSAGYG----------------VLSSPRQQGGGMMMGPGGGGAASLSKAAAG 338 Query: 868 AAVAG---NPGSDYFPGGTAP------GAPGPGGPS--GTSSSGSKASGPPNPPAQGDGT 916 +A G G + P G P +P P S G+ S S PP PP+Q Sbjct: 339 SAAGGFQRFAGQNQHPSGATPTLNQLLTSPSPMMRSYGGSYPEYSSPSAPPPPPSQPQSQ 398 Query: 917 SLSPNYTLESTSGNDGKPVSGGGGRGRGRRKRDSGHVSPGTFFDKYSAAPDSGGAPGVSP 976 + + + + G+ + G G G+ + + + S S G PG + Sbjct: 399 AAA------AGAAAGGQQAAAGMGLGKDMGAQYAAASPAWAAAQQRSHPAMSPGTPGPTM 452 Query: 977 GQQQAS 982 G+ Q S Sbjct: 453 GRSQGS 458 Score = 81.6 bits (200), Expect = 4e-15 Identities = 230/994 (23%), Positives = 308/994 (30%), Gaps = 251/994 (25%) Query: 44 PPGPVDPAMSALGE----PPILGMNMEPYGFHARGHSELHAGGLQAQPV----------- 88 PPGP P +S G+ PP +G EP G H L A G Q PV Sbjct: 115 PPGP--PLLSKPGDEDDAPPKMG---EPAGGRYE-HPGLGALGTQQPPVAVPGGGGGPAA 168 Query: 89 ----HGFFGGQQPHHGHPGSHHPHQHHPHFGGNFGGPDPGASCLHGGRLLGYGGAAGGLG 144 + ++G P G PG + P F + G PG +H AAG G Sbjct: 169 VPEFNNYYGSAAPASGGPGG----RAGPCFDQHGGQQSPGMGMMHSAS----AAAAGAPG 220 Query: 145 SQPPFAEGYEHMAESQGPESFGPQRPGNLPDFHSSGASSHAVPAPCLPLDQSPNRAASFH 204 S P +E SQ G RPG G + Sbjct: 221 SMDPLQNSHEGYPNSQCNHYPGYSRPGAGGGGGGGGGGGGG------------SGGGGGG 268 Query: 205 GLPSSSGSDSHSLEPRRVTNQGAVDSLEYNYPGEAPSGHFDMFSPSDSEGQLPHYAAGRQ 264 G + G+ + ++ A G + +G+ + SP RQ Sbjct: 269 GGAGAGGAGAGAVAAAAAAAAAAAGGGGGGGYGGSSAGYGVLSSP-------------RQ 315 Query: 265 VPGGAFPGASAMPRAAGMVGLSKMHAQPPQQQPQQQQQPQQQQQQHGVFFERFSGARKMP 324 GG G P G LSK A F+RF+G + P Sbjct: 316 QGGGMMMG----PGGGGAASLSKAAAGSAAGG-----------------FQRFAGQNQHP 354 Query: 325 VGLEPSVGSRHPLMQPPQQAPPPPQQQPPQQPPQQQPPPPPGLLVRQNSCPPALPRPQQG 384 G P++ L+ P P + P P PP PP+ P+ Q Sbjct: 355 SGATPTLNQ---LLTSPS---PMMRSYGGSYPEYSSPSAPPP--------PPSQPQSQAA 400 Query: 385 EAGTPSGGLQDGGPMLPSQHAQFEYPIHRLENRSMHPYSEPVFSMQHPPPQQAPNQRLQH 444 AG +GG Q M + +Y + S P S P P +Q Sbjct: 401 AAGAAAGGQQAAAGMGLGKDMGAQYAAASPAWAAAQQRSHPAMSPGTPGPTMGRSQ---- 456 Query: 445 FDAPPYMNVAKRPRFDFPGSAGVDRCASWNGSMHNGALDNHLSP---SAYPGLPGEFTPP 501 +P V KRP+ GS + H P S YPG G + PP Sbjct: 457 -GSPMDPMVMKRPQLYGMGS------------------NPHSQPQQSSPYPG--GSYGPP 495 Query: 502 VPDSFPSGPPLQHPA-------PDHQS-------------------------LQQQQQQQ 529 P +P G + P P Q QQ QQ Sbjct: 496 GPQRYPIGIQGRTPGAMAGMQYPQQQDSGDATWKETFWLMPPQYGQQGVSGYCQQGQQPY 555 Query: 530 QQQQQQ-------------QQQQQQQQQQQQQQQRQNAALMIKQMASRNQQQRLRQPNLA 576 QQ Q Q QQ+ Q QQ Q+ + + L NL Sbjct: 556 YSQQPQPPHLPPQAQYLPSQSQQRYQPQQDMSQEGYGTRSQPPLAPGKPNHEDL---NLI 612 Query: 577 QLGHPGDVGQ-GGLVHGGPVGGLAQ-PNFEREGGSTGAGRLGTFEQQAPHLAQESAWFS- 633 Q P + G + P G A + GST + + Q+P S S Sbjct: 613 QQERPSSLPDLSGSIDDLPTGTEATLSSAVSASGSTSSQGDQSNPAQSPFSPHASPHLSS 672 Query: 634 ---GPHPPP-GDLLPRRMGGSGLPADCGPHDPSLAPPPPPGGSG------VLFRGPL-QE 682 GP P P G + SG P S PP PPG L + P+ QE Sbjct: 673 IPGGPSPSPVGSPVGSNQSRSG-PISPASIPGSQMPPQPPGSQSESSSHPALSQSPMPQE 731 Query: 683 PMRMPGEGHVPAL---------------PSPGLQFGGSL-------------------GG 708 M G P + PSPG Q + G Sbjct: 732 RGFMAGTQRNPQMAQYGPQQTGPSMSPHPSPGGQMHAGISSFQQSNSSGTYGPQMSQYGP 791 Query: 709 LGQLQSPGAGVGLPSAASERRPPPPDFATSA---LGGQ-PGFPFGA--------AGRQST 756 G P A G+PSA+ P P SA + GQ P P GA AG Q+ Sbjct: 792 QGNYSRPPAYSGVPSASYS--GPGPGMGISANNQMHGQGPSQPCGAVPLGRMPSAGMQNR 849 Query: 757 PHSGPGVNSPPSAGGGGGSSGGGGGGGAYPPQPDF-QPSQRTSASKLGALSLGSFNKPSS 815 P G + PS+ G G G G PP P + +Q +A+ + A + + ++ S Sbjct: 850 PFPGNMSSMTPSSPGMSQQGGPGMG----PPMPTVNRKAQEAAAAVMQAAANSAQSRQGS 905 Query: 816 KDNLFGQSCLAALSTACQNMIASLGAPNLNVTFNKKNPPEGKRKLSQNETD---GAAVAG 872 + +A+ S Q M N + N + PP N + G A Sbjct: 906 FPGMNQSGLMASSSPYSQPM------NNSSSLMNTQAPPYSMAPAMVNSSAASVGLADMM 959 Query: 873 NPGSDYFP-----GGTAPGAPGPGGPSGTSSSGS 901 +PG P G G P P S SSS + Sbjct: 960 SPGESKLPLPLKADGKEEGTPQPESKSKKSSSST 993 Score = 78.6 bits (192), Expect = 4e-14 Identities = 174/807 (21%), Positives = 261/807 (32%), Gaps = 123/807 (15%) Query: 31 NTHFKAPAFHTGGPPGPVDPAMSALGEPPILGMNMEPYGFHARGHSELHAGGLQAQPVHG 90 N ++ + A +GGP G P G GM M +H+ A G Sbjct: 173 NNYYGSAAPASGGPGGRAGPCFDQHGGQQSPGMGM------------MHSASAAAAGAPG 220 Query: 91 FFGG-QQPHHGHPGS---HHPHQHHPHFGGNFGGPDPGASCLHGGRLLGYGGAAG-GLGS 145 Q H G+P S H+P P GG GG G GG G GA G G G+ Sbjct: 221 SMDPLQNSHEGYPNSQCNHYPGYSRPGAGGGGGGGGGGGGGSGGGGGGGGAGAGGAGAGA 280 Query: 146 QPPFAEGYEHMAESQGPESFGPQRPG----NLPDFHSSGASSHAVPAPCLPLDQSPNRAA 201 A A G +G G + P G L ++ +A Sbjct: 281 VAAAAAAAAAAAGGGGGGGYGGSSAGYGVLSSPRQQGGGMMMGPGGGGAASLSKAAAGSA 340 Query: 202 SFHGLPSSSGSDSHSLEPRRVTNQ--GAVDSLEYNYPGEAPSGHFDMFSPSDSEGQLPHY 259 + G +G + H NQ + + +Y G P + +P Q Sbjct: 341 A-GGFQRFAGQNQHPSGATPTLNQLLTSPSPMMRSYGGSYPE-YSSPSAPPPPPSQPQSQ 398 Query: 260 AAGRQVPGGAFPGASAMPRAAGMVGLSKMHAQPPQQQPQQQQQPQQQQQQHGVFFERFSG 319 AA G A+ M M G A P QQ+ P G R G Sbjct: 399 AAAAGAAAGGQQAAAGMGLGKDM-GAQYAAASPAWAAAQQRSHPAMSPGTPGPTMGRSQG 457 Query: 320 ARKMPVGLEP----SVGSRHPLMQPPQQAPPPPQQQPPQQPPQQQPPPPPGLLVRQNSCP 375 + P+ ++ +GS +P QP Q +P P P P + P G+ R Sbjct: 458 SPMDPMVMKRPQLYGMGS-NPHSQPQQSSPYPGGSYGPPGPQRY----PIGIQGRTPGAM 512 Query: 376 PALPRPQQGEAGTPSGGLQDGGPMLPSQHAQFEYPIHRLENRSMHPYSEPVFSMQHPPP- 434 + PQQ ++G + ++ ++P Q+ Q + + PY H PP Sbjct: 513 AGMQYPQQQDSGDAT--WKETFWLMPPQYGQ--QGVSGYCQQGQQPYYSQQPQPPHLPPQ 568 Query: 435 -QQAPNQRLQHF--------------DAPPY---------MNVAKRPR-----------F 459 Q P+Q Q + PP +N+ ++ R Sbjct: 569 AQYLPSQSQQRYQPQQDMSQEGYGTRSQPPLAPGKPNHEDLNLIQQERPSSLPDLSGSID 628 Query: 460 DFPGSAGVDRCASWNGSMHNGALDNHLSPSAYPGLPGEFTPPVPDSFPSGP---PLQHPA 516 D P ++ + S + + +P+ P P P S P GP P+ P Sbjct: 629 DLPTGTEATLSSAVSASGSTSSQGDQSNPAQSPFSP--HASPHLSSIPGGPSPSPVGSPV 686 Query: 517 PDHQ---------SLQQQQQQQQQQQQQQQQQQQQQQQQQQQQRQNAALMIKQMASRNQQ 567 +Q S+ Q Q Q + Q ++ + Q + Q Sbjct: 687 GSNQSRSGPISPASIPGSQMPPQPPGSQSESSSHPALSQSPMPQERGFMAGTQRNPQMAQ 746 Query: 568 QRLRQPNLAQLGHPGDVGQGGLVHGGPVGGLAQPNFEREGG--STGAGRLGTFEQQAPHL 625 +Q + HP GG +H G + Q N G + G G + + + Sbjct: 747 YGPQQTGPSMSPHP---SPGGQMHAG-ISSFQQSNSSGTYGPQMSQYGPQGNYSRPPAYS 802 Query: 626 AQESAWFSGPHPPPGDLLPRRMGGSGLPADCGPHDPSLAPPPPPGGSGVLFRGPLQEPMR 685 SA +SGP P G +M G G P P G+ L R P Sbjct: 803 GVPSASYSGPGPGMGISANNQMHGQG--------------PSQPCGAVPLGRMPSAGMQN 848 Query: 686 MPGEGHVPALPSPGLQFGGSLGGLGQLQSPGAGVGLPS-------AASERRPPPPDFATS 738 P G++ ++ S G+ Q PG G +P+ AA+ + A S Sbjct: 849 RPFPGNMSSMTP-------SSPGMSQQGGPGMGPPMPTVNRKAQEAAAAVMQAAANSAQS 901 Query: 739 ALGGQPGFPFGAAGRQSTPHSGPGVNS 765 G PG S+P+S P NS Sbjct: 902 RQGSFPGMNQSGLMASSSPYSQPMNNS 928 Score = 66.6 bits (161), Expect = 1e-10 Identities = 119/475 (25%), Positives = 168/475 (35%), Gaps = 65/475 (13%) Query: 703 GGSLGGLGQ----LQSPGAGVGLPSAASERRPPPPDFATSALGGQPGFP----FGAAGRQ 754 GG+ GG Q ++ P G SAA + PP S G + P A GR Sbjct: 83 GGAGGGAPQPGPDMEQPQHGGAKDSAAGGQADPPGPPLLSKPGDEDDAPPKMGEPAGGRY 142 Query: 755 STPHSGP-GVNSPPSAGGGGGSSGGGGGGGAYPPQPDFQPSQRTSASKLGALSLGSFNKP 813 P G G PP A GGGGG A P ++ S ++ G + F++ Sbjct: 143 EHPGLGALGTQQPPVA-----VPGGGGGPAAVPEFNNYYGSAAPASGGPGGRAGPCFDQH 197 Query: 814 SSKDNLFGQSCLAALSTACQNMIASLGAPNLNVTFNKKNPPEGKRKLSQNETDGAAVAGN 873 + + G + + S A + GAP G QN +G N Sbjct: 198 GGQQSP-GMGMMHSASAA------AAGAP-------------GSMDPLQNSHEGYP---N 234 Query: 874 PGSDYFPGGTAPGAPGPGGPSGTSSSGSKASGPPNPPAQGDGTSLSPNYTLESTSGNDGK 933 +++PG + PGA G GG G GS G G G + + + + Sbjct: 235 SQCNHYPGYSRPGAGGGGGGGGGGGGGSGGGGGGG----GAGAGGAGAGAVAAAAAAAAA 290 Query: 934 PVSGGGGRGRGRRKRDSGHVS-PGTFFDKYSAAPDSGGAPGVSPGQQQASGAAVGGSS-- 990 GGGG G G G +S P P GGA +S + A+G+A GG Sbjct: 291 AAGGGGGGGYGGSSAGYGVLSSPRQQGGGMMMGPGGGGAASLS---KAAAGSAAGGFQRF 347 Query: 991 AGETR---GAPTPHEKALTSPS---WGKGAELLLGDQPDLIGSLDGGAKSDSSSPNVGEF 1044 AG+ + GA + LTSPS G P +S +++ Sbjct: 348 AGQNQHPSGATPTLNQLLTSPSPMMRSYGGSYPEYSSPSAPPPPPSQPQSQAAAAGAAAG 407 Query: 1045 ASDEVSTSYANEDEVSSSSDNPQALVKASRSPLVTGSPKLPPRGVGAGEHGPKAP----- 1099 + +D + + A A + SP P +G + P P Sbjct: 408 GQQAAAGMGLGKDMGAQYAAASPAWAAAQQRSHPAMSPGTPGPTMGRSQGSPMDPMVMKR 467 Query: 1100 PPALGLGIMSNSTSTPDS---YGGG--GGPGHPGTPGLEQVRTPTSSSGAPPPDE 1149 P G+G SN S P Y GG G PG P Q RTP + +G P + Sbjct: 468 PQLYGMG--SNPHSQPQQSSPYPGGSYGPPGPQRYPIGIQGRTPGAMAGMQYPQQ 520 Score = 56.2 bits (134), Expect = 2e-07 Identities = 109/462 (23%), Positives = 164/462 (35%), Gaps = 81/462 (17%) Query: 95 QQPHHGHPGSHHPHQHHPHFGGNFGGPDPG-------ASCLHGGRLLGYGGAAGGLGSQP 147 Q P + GS Q G N PG AS HG GG + + Sbjct: 1121 QPPSPANSGSLQGPQTPQSTGSNSMAEVPGDLKPPTPASTPHGQMTPMQGGRSSTISVHD 1180 Query: 148 PFAEGYEHMAESQGPE--SFGPQRPGNLPDFHSSGASSHAVPAPCLPLDQSPNRAASFHG 205 PF++ +++S P+ S P P + G S +P + PN+ F G Sbjct: 1181 PFSD----VSDSSFPKRNSMTPNAP------YQQGMS---MPDVMGRMPYEPNKDP-FGG 1226 Query: 206 LPSSSGSDSHSLEPRRVTNQGAVDSLEYNYPGEAPSGHFDMFSPSDSEGQLPHYAA---- 261 + GS + ++ N D YN ++PSG + Q P+ A+ Sbjct: 1227 MRKVPGSSEPFMTQGQMPNSSMQDM--YN---QSPSGAMSNLGMGQRQ-QFPYGASYDRR 1280 Query: 262 ----GRQVPGGAFPGASAMPRAAGMVGLS------KMHAQ----PPQQQPQ----QQQQP 303 G+Q PG P + P GL K H PP ++ + Q Sbjct: 1281 HEPYGQQYPGQG-PPSGQPPYGGHQPGLYPQQPNYKRHMDGMYGPPAKRHEGDMYNMQYS 1339 Query: 304 QQQQQQHGVFFERFSGARKMPV-GLEPSVGSRHPLMQPPQ---QAPPPPQQQPPQQPPQQ 359 QQQ+ + + +SG + P+ G P SR + P Q PP P Q Sbjct: 1340 SQQQEMYNQYGGSYSGPDRRPIQGQYPYPYSRERMQGPGQIQTHGIPPQMMGGPLQSSSS 1399 Query: 360 QPPPPPGLLVRQNSCPPALPRPQQGEAGTPSGGLQDGGPMLPSQHAQFEY--PIHRLENR 417 + P R + +P P Q G P G Q P P + + P R+ + Sbjct: 1400 EGPQQNMWAARND-----MPYPYQNRQG-PGGPTQ--APPYPGMNRTDDMMVPDQRINHE 1451 Query: 418 SMHPYSEPVFSMQHPPPQQAPNQRLQHFDAPPYMNVAKRPRFDFPGSAGVDRCASWNGSM 477 S P + P + + +Q PP +P + P S + + + Sbjct: 1452 SQWPSH-----VSQRQPYMSSSASMQPITRPP------QPSYQTPPSLPNHISRAPSPAS 1500 Query: 478 HNGALDNHLSPSAYPGLPG----EFTPPVPDSFPSGPPLQHP 515 +L+N +SPS P LP + P VP S +GPP Q P Sbjct: 1501 FQRSLENRMSPSKSPFLPSMKMQKVMPTVPTSQVTGPPPQPP 1542 Score = 52.8 bits (125), Expect = 2e-06 Identities = 207/923 (22%), Positives = 264/923 (28%), Gaps = 200/923 (21%) Query: 335 HPLMQPPQQAPPPPQQQPPQQPPQQQPPPPPGLLVRQNSCPPALPRPQQGEAGTPSGGLQ 394 H L Q Q QQQ QQ QQQ P + NS G GG Sbjct: 46 HALQQQLNQFQQQQQQQQQQQQQQQQQQHP---ISNNNSL------------GGAGGGAP 90 Query: 395 DGGPMLPSQHAQFEYPIHRLENRSMHPYSEPVFSMQHPPPQQAPNQRLQHFDAPPYMNVA 454 GP E P H S PP ++ DAPP M Sbjct: 91 QPGP-------DMEQPQHGGAKDSA------AGGQADPPGPPLLSKPGDEDDAPPKMGEP 137 Query: 455 KRPRFDFPGSAGVDRCASWNGSMHNGALDNHLSPSAYPGLPG--EFTPPVPDSFPSGPPL 512 R++ PG GAL P A PG G P + + S P Sbjct: 138 AGGRYEHPGL---------------GALGTQQPPVAVPGGGGGPAAVPEFNNYYGSAAPA 182 Query: 513 QHPAPDHQSLQQQQQQQQQQQQQQQQQQQQQQQQQQQQRQNAALMIKQMASRNQQQRLRQ 572 P ++ Q QQ L N Q Sbjct: 183 SG-GPGGRAGPCFDQHGGQQSPGMGMMHSASAAAAGAPGSMDPLQNSHEGYPNSQCN-HY 240 Query: 573 PNLAQLGHPGDVGQGGLVHGGPVGGLAQPNFEREGGSTGAGRLGTFEQQAPHLAQESA-- 630 P ++ G G G GG GG GG GG GAG G A A +A Sbjct: 241 PGYSRPGAGGGGGGGGGGGGGSGGGGG-------GGGAGAGGAGAGAVAAAAAAAAAAAG 293 Query: 631 -----WFSGPHPPPGDLLPRRMGGSGL---PADCGPHDPSLAPPPPPGGSGVLFRGPLQE 682 + G G L R G G+ P G S A G F G Q Sbjct: 294 GGGGGGYGGSSAGYGVLSSPRQQGGGMMMGPGGGGAASLSKAAAGSAAGGFQRFAGQNQH 353 Query: 683 PM-RMPGEGHVPALPSPGLQ-FGGSL-----------------------GGLGQLQSPGA 717 P P + PSP ++ +GGS G Q A Sbjct: 354 PSGATPTLNQLLTSPSPMMRSYGGSYPEYSSPSAPPPPPSQPQSQAAAAGAAAGGQQAAA 413 Query: 718 GVGLPS-------------AASERRPPP---PDFATSALGGQPGFPFGAA--------GR 753 G+GL AA+++R P P +G G P G Sbjct: 414 GMGLGKDMGAQYAAASPAWAAAQQRSHPAMSPGTPGPTMGRSQGSPMDPMVMKRPQLYGM 473 Query: 754 QSTPHSGPGVNSPPSAGGGG------------GSSGGGGGGGAYPPQPD----------- 790 S PHS P +SP G G G + G G YP Q D Sbjct: 474 GSNPHSQPQQSSPYPGGSYGPPGPQRYPIGIQGRTPGAMAGMQYPQQQDSGDATWKETFW 533 Query: 791 FQPSQRTSASKLGALSLGS---FNKPSSKDNLFGQSCLAALSTACQNMIASLGAPNLNVT 847 P Q G G +++ +L Q+ L + Q + Sbjct: 534 LMPPQYGQQGVSGYCQQGQQPYYSQQPQPPHLPPQA--QYLPSQSQQRYQPQQDMSQEGY 591 Query: 848 FNKKNPPEGKRK-------LSQNETDGAAVAGNPGSDYFPGGTAPGAPGPGGPSGTSSSG 900 + PP K L Q E + + D P GT SG++SS Sbjct: 592 GTRSQPPLAPGKPNHEDLNLIQQERPSSLPDLSGSIDDLPTGTEATLSSAVSASGSTSSQ 651 Query: 901 SKASGPPNPPAQGDGTSLSPNYTLESTSGNDGKPVSGGGGRGRGRRKRDSGHVSPGTFFD 960 S P P SP+ + S G P G G + SG +SP Sbjct: 652 GDQSNPAQSP-------FSPHAS-PHLSSIPGGPSPSPVGSPVGSNQSRSGPISP----- 698 Query: 961 KYSAAPDSGGAPGVSPGQQQASGAAVGGSSAGETRGAPTPHEKALTSPSWGKGAELLLGD 1020 A+ P PG Q S SS +P P E+ + + G Sbjct: 699 ---ASIPGSQMPPQPPGSQSES------SSHPALSQSPMPQERGFMAGTQRNPQMAQYGP 749 Query: 1021 QPDLIGSLDGGAKSDSSSPN------VGEFASDEVSTSYANEDEVSSSSDNPQALVKASR 1074 Q G + S SP + F S +Y + S PQ SR Sbjct: 750 QQT------GPSMSPHPSPGGQMHAGISSFQQSNSSGTYGPQ----MSQYGPQG--NYSR 797 Query: 1075 SPLVTGSPKLPPRGVGAGE----------HGPKAPPPALGLGIMSNSTSTPDSYGGGGGP 1124 P +G P G G G GP P A+ LG M ++ + G Sbjct: 798 PPAYSGVPSASYSGPGPGMGISANNQMHGQGPSQPCGAVPLGRMPSAGMQNRPFPGNMSS 857 Query: 1125 GHPGTPGLEQVRTPTSSSGAPPP 1147 P +PG+ Q P G P P Sbjct: 858 MTPSSPGMSQQGGP--GMGPPMP 878 Score = 45.1 bits (105), Expect = 5e-04 Identities = 161/785 (20%), Positives = 251/785 (31%), Gaps = 195/785 (24%) Query: 142 GLGSQPPFAEGYEHMAESQGPESFGPQRPGNLPDFHSSGASSHAVPAPCLPLDQSPNRA- 200 G SQPP A G + + + +RP +LPD S +D P Sbjct: 592 GTRSQPPLAPGKPNHEDLNLIQQ---ERPSSLPDLSGS-------------IDDLPTGTE 635 Query: 201 ASFHGLPSSSGSDSHSLEPRRVTNQGAVDSLEYNYPGEAPSGHFDMFSPSDSEGQLPHYA 260 A+ S+SGS S +QG + + P ++P FSP S PH + Sbjct: 636 ATLSSAVSASGSTS---------SQG-----DQSNPAQSP------FSPHAS----PHLS 671 Query: 261 AGRQVPGGAFPGASAMPRAAGMVGLSKMHAQP--PQQQPQQQQQPQQQQQQHGVFFERFS 318 + +PGG P P VG ++ + P P P Q PQ Q S Sbjct: 672 S---IPGGPSPSPVGSP-----VGSNQSRSGPISPASIPGSQMPPQPPGSQ--------S 715 Query: 319 GARKMPVGLEPSVGSRHPLMQPPQQAPPPPQQQPPQQPPQQQPPPPP------GLLVRQN 372 + P + + M Q+ P Q P Q P P P P G+ Q Sbjct: 716 ESSSHPALSQSPMPQERGFMAGTQRNPQMAQYGPQQTGPSMSPHPSPGGQMHAGISSFQQ 775 Query: 373 SCPPALPRPQQGE-------------AGTPSGGLQDGGPML------------PSQHAQF 407 S PQ + +G PS GP + PSQ Sbjct: 776 SNSSGTYGPQMSQYGPQGNYSRPPAYSGVPSASYSGPGPGMGISANNQMHGQGPSQPCGA 835 Query: 408 ----EYPIHRLENR-------SMHPYSEPVFSMQHP---PPQQAPNQRLQHFDAPPYM-- 451 P ++NR SM P S + P PP N++ Q A Sbjct: 836 VPLGRMPSAGMQNRPFPGNMSSMTPSSPGMSQQGGPGMGPPMPTVNRKAQEAAAAVMQAA 895 Query: 452 -NVAKRPRFDFPGSAGVDRCASWNGSMHNGALDNHLSPSAYPGLPGEFTPPVPDSFPSGP 510 N A+ + FPG AS S ++ ++N S P P + +S + Sbjct: 896 ANSAQSRQGSFPGMNQSGLMAS--SSPYSQPMNNSSSLMNTQAPPYSMAPAMVNSSAASV 953 Query: 511 PLQHP-APDHQSLQQQQQQQQQQQQQQQQQQQQQQQQQQQQRQNAALMIKQMASRNQQQR 569 L +P L + +++ Q + + ++ + ++ + +++ Sbjct: 954 GLADMMSPGESKLPLPLKADGKEEGTPQPESKSKKSSSSTTTGEKITKVYELGNEPERKL 1013 Query: 570 LRQPNLAQLGHPGD-------VGQGGL------VHGGPVGGLAQPNFEREGGSTGAG-RL 615 L + G VG+ L V +GGLAQ N ++ + Sbjct: 1014 WVDRYLTFMEERGSPVSSLPAVGKKPLDLFRLYVCVKEIGGLAQVNKNKKWRELATNLNV 1073 Query: 616 GTFEQQAPHLAQESAWF---------SGPHPPP--------------------------G 640 GT A L ++ + G PPP G Sbjct: 1074 GTSSSAASSLKKQYIQYLFAFECKIERGEEPPPEVFSTGDTKKQPKLQPPSPANSGSLQG 1133 Query: 641 DLLPRRMGGSGL---PADCGPHDPSLAP----PPPPGG---------------------- 671 P+ G + + P D P P+ P P GG Sbjct: 1134 PQTPQSTGSNSMAEVPGDLKPPTPASTPHGQMTPMQGGRSSTISVHDPFSDVSDSSFPKR 1193 Query: 672 SGVLFRGPLQEPMRMPGE-GHVPALPSPGLQFGGSLGGLGQLQSPGAGVGLPSAASE--- 727 + + P Q+ M MP G +P P+ FGG G + +P+++ + Sbjct: 1194 NSMTPNAPYQQGMSMPDVMGRMPYEPNKD-PFGGMRKVPGSSEPFMTQGQMPNSSMQDMY 1252 Query: 728 RRPPPPDFATSALGGQPGFPFGAAGRQSTPHSGPGVNSPPSAGGGGGSSGGGGGGGAYPP 787 + P + +G + FP+GA+ H G P G GG G YP Sbjct: 1253 NQSPSGAMSNLGMGQRQQFPYGAS--YDRRHEPYGQQYPGQGPPSGQPPYGGHQPGLYPQ 1310 Query: 788 QPDFQ 792 QP+++ Sbjct: 1311 QPNYK 1315 Score = 41.6 bits (96), Expect = 0.005 Identities = 33/102 (32%), Positives = 40/102 (39%), Gaps = 14/102 (13%) Query: 294 QQQPQQQQQPQQQQQQHGVFFERFSGARKMPVGLEPSVGSRHPLMQPPQQAPPPPQQQPP 353 QQQ QQQQQ QQQQQQH + G G P P + P + Sbjct: 58 QQQQQQQQQQQQQQQQHPISNNNSLG----------GAGGGAPQPGPDMEQPQHGGAKDS 107 Query: 354 QQPPQQQPPPPPGLLVR---QNSCPPALPRPQQGEAGTPSGG 392 Q PP PP LL + ++ PP + P G P G Sbjct: 108 AAGGQADPPGPP-LLSKPGDEDDAPPKMGEPAGGRYEHPGLG 148 Score = 33.1 bits (74), Expect = 1.8 Identities = 81/347 (23%), Positives = 117/347 (33%), Gaps = 83/347 (23%) Query: 51 AMSALGEPPILGMNME-PYGFHARGHSELHAGGLQAQPVHGFFGGQQPHHGHPGSHHPHQ 109 AMS LG +G + PYG + H Q P G GQ P+ GH +P Q Sbjct: 1259 AMSNLG----MGQRQQFPYG---ASYDRRHEPYGQQYPGQGPPSGQPPYGGHQPGLYPQQ 1311 Query: 110 --HHPHFGGNFGGPDPGASCLHGGRLLG-------------YGGAAGGLGSQPPFAEGYE 154 + H G +G P + H G + YGG+ G +P Sbjct: 1312 PNYKRHMDGMYGPP----AKRHEGDMYNMQYSSQQQEMYNQYGGSYSGPDRRP------- 1360 Query: 155 HMAESQGPESFGPQR---PGNLPDFHSSGASSHAVPAPCLPLDQSPNRAASFHGLPSSSG 211 + Q P + +R PG + +H +P + P +++S G + Sbjct: 1361 --IQGQYPYPYSRERMQGPGQI--------QTHGIPPQMM---GGPLQSSSSEGPQQNMW 1407 Query: 212 SDSHSLEPRRVTNQGAVDSLEY-NYPGEAPSGHFDMFSPS---DSEGQLPHYAAGRQVPG 267 + + + QG + YPG + DM P + E Q P + + RQ Sbjct: 1408 AARNDMPYPYQNRQGPGGPTQAPPYPGMNRTD--DMMVPDQRINHESQWPSHVSQRQ--- 1462 Query: 268 GAFPGASAMPRAAGMVGLSKMHAQPPQQQPQQQQQPQQQQQQH-GVFFERFSGARKMPVG 326 M +A M QP + PQ Q H S R + Sbjct: 1463 ------PYMSSSASM--------QPITRPPQPSYQTPPSLPNHISRAPSPASFQRSLENR 1508 Query: 327 LEPSVGSRHPLMQPPQQAPPPPQQQPPQQPPQQQPPP-------PPG 366 + PS P M+ + P P Q PP QPPP PPG Sbjct: 1509 MSPSKSPFLPSMKMQKVMPTVPTSQVTGPPP--QPPPIRREITFPPG 1553 Score = 30.8 bits (68), Expect = 9.0 Identities = 76/358 (21%), Positives = 108/358 (30%), Gaps = 47/358 (13%) Query: 43 GPPGPVDPAMSALGEPPILGMN----MEPYGFHARGHSELHAGGLQAQPVHGFFGGQQPH 98 G + A+SA G G P+ HA H GG PV G Q Sbjct: 633 GTEATLSSAVSASGSTSSQGDQSNPAQSPFSPHASPHLSSIPGGPSPSPVGSPVGSNQSR 692 Query: 99 HG---------------HPGSHHPHQHHPHFGGNFGGPDPG--ASCLHGGRLLGYGGAAG 141 G PGS HP + + G A ++ YG Sbjct: 693 SGPISPASIPGSQMPPQPPGSQSESSSHPALSQSPMPQERGFMAGTQRNPQMAQYGPQQT 752 Query: 142 GLGSQP-PFAEGYEH-----MAESQGPESFGPQR-----PGNL---PDFHSSGASSHAVP 187 G P P G H +S ++GPQ GN P + ++S++ P Sbjct: 753 GPSMSPHPSPGGQMHAGISSFQQSNSSGTYGPQMSQYGPQGNYSRPPAYSGVPSASYSGP 812 Query: 188 APCLPLDQSPNRAASFHGLPSSSGSDSHSLEPRRVTNQ----GAVDSLEYNYPGEAPSGH 243 P + + S N G G+ P G + S+ + PG + G Sbjct: 813 GPGMGI--SANNQMHGQGPSQPCGAVPLGRMPSAGMQNRPFPGNMSSMTPSSPGMSQQGG 870 Query: 244 FDMFSPSDSEGQLPHYAAGRQVPGGAFPGASAMPRAAGMVGLSKMHAQPPQQQPQQQQQP 303 M P + + AA + A S GM M + P QP Sbjct: 871 PGMGPPMPTVNRKAQEAAAAVMQAAANSAQSRQGSFPGMNQSGLMASSSPYSQPMNNSSS 930 Query: 304 QQQQQQHGVFFERFSGARKMPVGLEPSVGSRHPLMQPPQQAPPPPQQQPPQQPPQQQP 361 Q +S A M SVG +M P + P P + ++ QP Sbjct: 931 LMNTQA-----PPYSMAPAMVNSSAASVGLA-DMMSPGESKLPLPLKADGKEEGTPQP 982 >gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo sapiens] Length = 5537 Score = 91.7 bits (226), Expect = 4e-18 Identities = 224/871 (25%), Positives = 290/871 (33%), Gaps = 198/871 (22%) Query: 156 MAESQGPESFGPQRPGNLPDFHSSGASSHAVPAPCLPLDQSPNRAASFHGLPSSSGSDSH 215 MAE + + Q+ HS+ + +P L L + P + HGL G Sbjct: 3592 MAEYRNKQQQQQQQQQQQQQQHSAVLALSPSQSPRL-LTKLPGQLLPGHGLQPPQGPPGG 3650 Query: 216 SLEPRRVTNQGAVDSLEYNYPGEAPSGHFDMFSPSDSEGQLPHYAAGRQV--PGGAFPGA 273 R+T G PG+ P G F + + + Q AG GG FPG Sbjct: 3651 QAGGLRLTPGGMA------LPGQ-PGGPFLNTALAQQQQQQHSGGAGSLAGPSGGFFPGN 3703 Query: 274 SAMPRAAGMVG--LSKMHAQPPQQQPQ-----QQQQPQQQQQQHGVFFERFSGARKMPVG 326 A+ R+ G L + Q QQ+ Q QQQQ QQQQQQH + Sbjct: 3704 LAL-RSLGPDSRLLQERQLQLQQQRMQLAQKLQQQQQQQQQQQHLL-------------- 3748 Query: 327 LEPSVGSRHPLMQPPQQAPPPPQQQPPQQPPQQQPPPPP--GLLVRQNSC-PPALPRPQQ 383 + + Q QQ P Q PQ PP GLLV+Q S PP P+ Sbjct: 3749 ------GQVAIQQQQQQGPGVQTNQALGPKPQGLMPPSSHQGLLVQQLSPQPPQGPQGML 3802 Query: 384 GEAGTPSGGLQDGGPMLPS-QHAQFEYPIHR-LENRSMHPYSEPVFSMQHPPPQQAPNQR 441 G A Q G + P H Q R L + + + + + QQ Q+ Sbjct: 3803 GPAQVAVLQQQHPGALGPQGPHRQVLMTQSRVLSSPQLAQQGQGLMGHRLVTAQQQQQQQ 3862 Query: 442 LQHFDAPPYMNVAKRPRFDFPGSAGVDRCASWNGSMHNGALDNHLSPSAYPGLPGEFTPP 501 QH + S G H + +S S P L + Sbjct: 3863 -QH-----------------------QQQGSMAGLSH--LQQSLMSHSGQPKLSAQ---- 3892 Query: 502 VPDSFPSGPPLQHPAPDHQSLQQQQQQQ-------QQQQQQQQQQQQQQQQQQQQQRQNA 554 P Q Q LQQQQQQQ QQQQ QQQQQQQQ QQQQQQQ Q Sbjct: 3893 -PMGSLQQLQQQQQLQQQQQLQQQQQQQLQQQQQLQQQQLQQQQQQQQLQQQQQQQLQQQ 3951 Query: 555 ALMIKQMASRNQQQRLRQPNLAQLG----------------------------------H 580 ++Q + QQQ +Q Q+G Sbjct: 3952 QQQLQQQQQQQQQQFQQQQQQQQMGLLNQSRTLLSPQQQQQQQVALGPGMPAKPLQHFSS 4011 Query: 581 PGDVGQGGLVHGGPVGGL--AQPNFEREGGSTGAG---RLGTF-EQQAPHLAQESAWFSG 634 PG +G L+ G + A + EG ST G +GT E A + SG Sbjct: 4012 PGALGPTLLLTGKEQNTVDPAVSSEATEGPSTHQGGPLAIGTTPESMATEPGEVKPSLSG 4071 Query: 635 ----------PHPPPGDLL---PRRMGG-----------------------SGLPADCGP 658 P P P L P R+ G S A P Sbjct: 4072 DSQLLLVQPQPQPQPSSLQLQPPLRLPGQQQQQVSLLHTAGGGSHGQLGSGSSSEASSVP 4131 Query: 659 H---DPSLAPPPPPGGSGVLFRGPLQEPMRMP---GEGHVPALPSPGLQFGGSLGG---- 708 H PS++ PG GP Q + P G P P P LQ G L G Sbjct: 4132 HLLAQPSVSLGDQPGSMTQNLLGPQQPMLERPMQNNTGPQPPKPGPVLQSGQGLPGVGIM 4191 Query: 709 --LGQLQSPGAGVGLPSAASERRPPPPDFATSALGGQPGFPFGAAGRQSTPHSGPGVNSP 766 +GQL++ GV + P AL Q A RQ+ P+ PG + Sbjct: 4192 PTVGQLRAQLQGVLAKNPQLRHLSPQQQQQLQALLMQRQLQQSQAVRQTPPYQEPGTQTS 4251 Query: 767 PSAGGGGGSSGGGGGGGAYPPQPDFQPSQRTSASKLGALSLGSFNKPSSKDNLFGQSCLA 826 P G G GG P P P Q LG+ +P L + Sbjct: 4252 PLQGLLGCQPQLGGF-----PGPQTGPLQ----------ELGAGPRPQGPPRL--PAPPG 4294 Query: 827 ALSTACQNMIASLG----APNLNVTFNKKNPPEGKRKLSQNETDGAAVAGNPGSDYFPGG 882 ALST LG P + K P + SQ T+ +PG+ G Sbjct: 4295 ALSTG-----PVLGPVHPTPPPSSPQEPKRPSQLPSPSSQLPTEAQLPPTHPGTPKPQGP 4349 Query: 883 TAPGAPGPGGPSGTSSSG---SKASGPPNPP 910 T PG P+ + SK GP +PP Sbjct: 4350 TLEPPPGRVSPAAAQLADTLFSKGLGPWDPP 4380 Score = 75.9 bits (185), Expect = 2e-13 Identities = 190/771 (24%), Positives = 247/771 (32%), Gaps = 195/771 (25%) Query: 286 SKMHAQPPQQQPQQQQQPQQQQQQHGVFFERFSGARKMPVGLEPSVGSRHPLMQPPQQAP 345 + + A+ +Q QQQQQ QQQQQQH + L PS R L + P Q Sbjct: 3589 TNLMAEYRNKQQQQQQQQQQQQQQHSAV-----------LALSPSQSPRL-LTKLPGQLL 3636 Query: 346 PPPQQQPPQQPPQQQPP----PPPGLLVRQNSCPP----ALPRPQQ----GEAGT---PS 390 P QPPQ PP Q P G+ + P AL + QQ G AG+ PS Sbjct: 3637 PGHGLQPPQGPPGGQAGGLRLTPGGMALPGQPGGPFLNTALAQQQQQQHSGGAGSLAGPS 3696 Query: 391 GGLQDGGPMLPSQHAQFEYPIHRLENRSMHPYSEPVFSMQHPPPQQAPNQRLQHFDAPPY 450 GG G L S L+ R + + + Q QQ Q+ QH Sbjct: 3697 GGFFPGNLALRSLGPDSRL----LQERQLQLQQQRMQLAQKLQQQQQQQQQQQHLLGQVA 3752 Query: 451 MNVAKR--PRFDFPGSAGVDRCASWNGSMHNGALDNHLSPSAYPGLPGEFTPPV------ 502 + ++ P + G S H G L LSP G G P Sbjct: 3753 IQQQQQQGPGVQTNQALGPKPQGLMPPSSHQGLLVQQLSPQPPQGPQGMLGPAQVAVLQQ 3812 Query: 503 --PDSF-PSGPPLQ------------------HPAPDHQSLQQQQQQQQQQQQQQ----- 536 P + P GP Q H+ + QQQQQQQQ QQQ Sbjct: 3813 QHPGALGPQGPHRQVLMTQSRVLSSPQLAQQGQGLMGHRLVTAQQQQQQQQHQQQGSMAG 3872 Query: 537 ----------------------------------QQQQQQQQQQQQQQRQNAALMIKQMA 562 QQQQQ QQQQQQQ +Q L +Q+ Sbjct: 3873 LSHLQQSLMSHSGQPKLSAQPMGSLQQLQQQQQLQQQQQLQQQQQQQLQQQQQLQQQQLQ 3932 Query: 563 SRNQQQRLRQPNLAQLGH------------------------------------PGDVGQ 586 + QQQ+L+Q QL P Q Sbjct: 3933 QQQQQQQLQQQQQQQLQQQQQQLQQQQQQQQQQFQQQQQQQQMGLLNQSRTLLSPQQQQQ 3992 Query: 587 GGLVHGGPVGGLAQPNFEREGGSTGAGRLGTFEQQAPHLAQESAWFSGPHPPPGDLLPRR 646 + G + +F G L EQ A S GP G L Sbjct: 3993 QQVALGPGMPAKPLQHFSSPGALGPTLLLTGKEQNTVDPAVSSEATEGPSTHQGGPLAIG 4052 Query: 647 MGGSGLPADCGPHDPSLA---------PPPPPGGSGVLFRGPLQEPMRMPG--EGHVPAL 695 + + G PSL+ P P P S + LQ P+R+PG + V L Sbjct: 4053 TTPESMATEPGEVKPSLSGDSQLLLVQPQPQPQPSSL----QLQPPLRLPGQQQQQVSLL 4108 Query: 696 PSPGLQFGGSLGGLGQLQSPGAGVGLPSAASERRPPPPDFATSALGGQPG-FPFGAAGRQ 754 + G GGS G LG S A +P ++ + +LG QPG G Q Sbjct: 4109 HTAG---GGSHGQLGSGSSSEAS-SVPHLLAQ--------PSVSLGDQPGSMTQNLLGPQ 4156 Query: 755 STPHSGPGVNS----PPSAGGGGGSSGGGGGGGAYPPQPDFQPSQRTSASKLGALSLGSF 810 P N+ PP G S G G G P + +L A G Sbjct: 4157 QPMLERPMQNNTGPQPPKPGPVLQSGQGLPGVGIMP-----------TVGQLRAQLQGVL 4205 Query: 811 NKPSSKDNLFGQSCLAALSTACQNMIASLGAPNLNVTFNKKNPPEGKRKLSQNETDGAAV 870 K +L Q + Q + A ++ PP + T + + Sbjct: 4206 AKNPQLRHLSPQQQQQLQALLMQRQLQQSQAV-------RQTPP-----YQEPGTQTSPL 4253 Query: 871 AGNPGSDYFPGGTAPGAPGP-GGPSGTSSSGSKASGPPNPPAQGDGTSLSP 920 G G G G PGP GP +G + GPP PA S P Sbjct: 4254 QGLLGCQPQLG----GFPGPQTGPLQELGAGPRPQGPPRLPAPPGALSTGP 4300 Score = 63.5 bits (153), Expect = 1e-09 Identities = 195/834 (23%), Positives = 265/834 (31%), Gaps = 189/834 (22%) Query: 37 PAFHTGGPPGPVDPAMS-ALGEPPILGMNMEPYGFHARGHSELHAGGLQAQPVHGFFGGQ 95 P F T P P P+ + A +PP+LG + P G Sbjct: 2187 PRFPTAPPTYPPYPSPTGAPAQPPMLGASSRP-------------------------GAG 2221 Query: 96 QPHHGHPGSHHPHQHHPHFGGNFGGPD-PGASCLHGGRLLGYGG--AAGGLGSQPPFAEG 152 QP H +H P F P P L G GG A+ L S PPF E Sbjct: 2222 QPGEFHTTPPGTPRHQPSTPDPFLKPRCPSLDNLAVPESPGVGGGKASEPLLSPPPFGES 2281 Query: 153 ---YEHMAESQGPES--FGPQRPGNLPDFHSSGASSHAVPAPCLPLDQSPNRAASFHGLP 207 E E G S +GP G + D SSG + + ++P + P Sbjct: 2282 RKALEVKKEELGASSPSYGPPNLGFV-DSPSSGTHLGGLELKTPDVFKAPLTPRASQVEP 2340 Query: 208 SSSGSDSHSLEPRRVTNQGAVDSLEYNYPGEAPSGHFDMFSP---SDSEGQLPHYAAGRQ 264 S G EP Q S P H D+F P +D Q P R Sbjct: 2341 QSPGLGLRPQEPPPA--QALAPS---------PPSHPDIFRPGSYTDPYAQPP--LTPRP 2387 Query: 265 VPGGAFPGASAMPRAAGMVGLSKMHAQPPQQQPQQQQQPQQQQQQHGVFFERFSGARKMP 324 P + PR+ S++ A P Q Q Q + E F P Sbjct: 2388 QPPPPESCCALPPRSLPSDPFSRVPASP-----QSQSSSQSPLTPRPLSAEAFC-----P 2437 Query: 325 VGLEPSVGSRHPLMQPPQQAPPPPQQQPPQQPPQQQPPP---PPGLLVRQN----SCPPA 377 + P S P +PP + P +PP+ QPP G L + P A Sbjct: 2438 SPVTPRFQSPDPYSRPPSRPQSRDPFAPLHKPPRPQPPEVAFKAGSLAHTSLGAGGFPAA 2497 Query: 378 LPRPQQGE--AGTPSGGLQD-------GGPMLPSQHAQFEYPIHRLENRSMHPYSEPVFS 428 LP GE A PSG + G + +F +P EP S Sbjct: 2498 LPAGPAGELHAKVPSGQPPNFVRSPGTGAFVGTPSPMRFTFP---------QAVGEP--S 2546 Query: 429 MQHPPPQQA---PNQRLQHFDAPPYMNVAKRPRFD------FPGSAGVDRCASWNGSMHN 479 ++ P PQ P+ HF P + + + P + + + G + Sbjct: 2547 LKPPVPQPGLPPPHGINSHFGPGPTLGKPQSTNYTVATGNFHPSGSPLGPSSGSTGESYG 2606 Query: 480 GALDNHLSPSAYPGLPGEFTPPVPDSFPSGPPLQHPAPDHQSLQQQQQQQQQ-------- 531 LSP P + PP PD S P L H A + ++++ Sbjct: 2607 ------LSPLRPPSV---LPPPAPDG--SLPYLSHGASQRSGITSPVEKREDPGTGMGSS 2655 Query: 532 ---------QQQQQQQQQQQQQQQQQQQRQNAALMIKQMASRNQQQRLRQPNLAQLGHPG 582 Q Q + ++Q+Q+++ L+I+Q RN ++ ++ A G G Sbjct: 2656 LATAELPGTQDPGMSGLSQTELEKQRQRQRLRELLIRQQIQRNTLRQEKETAAAAAGAVG 2715 Query: 583 DVGQGGLVHGGPVGGLAQPNFEREGGSTGAGRLGTFEQQAPHLAQESAWFSGPHPPPG-- 640 G G P FEQ L++ F+G Sbjct: 2716 PPGSWGAEPSSP----------------------AFEQ----LSRGQTPFAGTQDKSSLV 2749 Query: 641 DLLPRRMGGSGLPADCGPHDPSLAPPPPPG-------GSGVLFRGPLQEPMRMPGEGHVP 693 L P ++ G L P D L+ PPPP S L G R P G +P Sbjct: 2750 GLPPSKLSGPILGPGSFPSDDRLSRPPPPATPSSMDVNSRQLVGGSQAFYQRAPYPGSLP 2809 Query: 694 ALPSPGLQFGGSLGGLGQLQSPGAGVGLPSAASERRP--PPPDFATSALGGQPGFPFGAA 751 L Q L Q Q A + A S R P P P+ ALG P Sbjct: 2810 -LQQQQQQ-------LWQQQQATAATSMRFAMSARFPSTPGPELGRQALGS----PLAGI 2857 Query: 752 GRQSTPHSGPGVNSPPSAGGG-------GGSSGGGGGGGAYPPQ-----PDFQP 793 ST GPG P AG G G GG +P Q P F P Sbjct: 2858 ---STRLPGPGEPVPGPAGPAQFIELRHNVQKGLGPGGTPFPGQGPPQRPRFYP 2908 Score = 55.5 bits (132), Expect = 3e-07 Identities = 208/965 (21%), Positives = 291/965 (30%), Gaps = 199/965 (20%) Query: 141 GGLGSQPPFAEGYEHMAESQGPESFGPQRPGNLPDFHSSGASSHAVPAPCLPLDQSPNRA 200 G LGS PP A + P G L PA +P SP Sbjct: 2111 GALGSPPPAAAPTIFIGSPTTPAGLSTSADGFLKP-----------PAGSVPGPDSPGEL 2159 Query: 201 ASFHGLPSSSGSDSHSLEPRRVTNQGAVDSLEYNYPGEAPSGHFDMFSPSDSEGQLPHYA 260 F LP + S +P + LE +P AP + SP+ + Q P Sbjct: 2160 --FLKLPPQVPAQVPSQDPFGLA---PAYPLEPRFP-TAPPTYPPYPSPTGAPAQPPMLG 2213 Query: 261 AGRQVPGGAFPGASAMPRAAGMVGLSKMHAQPPQQQPQQQQQPQQQQQQHGVFFERFSGA 320 A + PG PG + H PP Q P + R Sbjct: 2214 ASSR-PGAGQPG--------------EFHTTPPGTPRHQPSTPDPFLKP------RCPSL 2252 Query: 321 RKMPVGLEPSVG---SRHPLMQPPQQAPPPPQQQPPQQPPQQQPPPPPGLLVRQNSCPPA 377 + V P VG + PL+ PP P + + + +++ + P+ Sbjct: 2253 DNLAVPESPGVGGGKASEPLLSPP----PFGESRKALEVKKEE----------LGASSPS 2298 Query: 378 LPRPQQGEAGTPSGGLQDGGPMLPSQHAQFEYPIHRLENRSMHPYSEPVFSMQHPPPQQA 437 P G +PS G GG LE ++ + P+ Q+ Sbjct: 2299 YGPPNLGFVDSPSSGTHLGG----------------LELKTPDVFKAPLTPRASQVEPQS 2342 Query: 438 PNQRLQHFDAPPYMNVAKRPRFDFPGSAGVDRCASWNGSMHNGALDNHLSPSAYPGLPGE 497 P L+ + PP +A P P + R S+ P A P L Sbjct: 2343 PGLGLRPQEPPPAQALAPSP----PSHPDIFRPGSYT------------DPYAQPPLTPR 2386 Query: 498 FTPPVPDSFPSGPPLQHPAPDHQSLQQQQQQQQQQQQQ--------------------QQ 537 PP P+S + PP P+ + Q Q Q Q Sbjct: 2387 PQPPPPESCCALPPRSLPSDPFSRVPASPQSQSSSQSPLTPRPLSAEAFCPSPVTPRFQS 2446 Query: 538 QQQQQQQQQQQQQRQNAALMIKQMASRNQQQRLRQPNLAQLGHPGDVGQGGL---VHGGP 594 + + Q R A + K + + + +LA +G GG + GP Sbjct: 2447 PDPYSRPPSRPQSRDPFAPLHKPPRPQPPEVAFKAGSLAHT----SLGAGGFPAALPAGP 2502 Query: 595 VGGL-------AQPNFEREGGSTGA--GRLGTFEQQAPHLAQESAWFSGPHPPPGDLLPR 645 G L PNF R G TGA G P E + P P PG P Sbjct: 2503 AGELHAKVPSGQPPNFVRSPG-TGAFVGTPSPMRFTFPQAVGEPS-LKPPVPQPGLPPPH 2560 Query: 646 RMGGSGLPAD-------------CGPHDPSLAPPPPPGGSGVLFRG--PLQEPMRMP--- 687 + P G PS +P P GS G PL+ P +P Sbjct: 2561 GINSHFGPGPTLGKPQSTNYTVATGNFHPSGSPLGPSSGSTGESYGLSPLRPPSVLPPPA 2620 Query: 688 GEGHVPALPSPGLQFGGSLGGLGQLQSPGAGVGLPSAASERRPPPPDFATSALGGQPGFP 747 +G +P L Q G + + + PG G+G S A+ P D S L Sbjct: 2621 PDGSLPYLSHGASQRSGITSPVEKREDPGTGMG-SSLATAELPGTQDPGMSGLSQTELEK 2679 Query: 748 FGAAGR------QSTPHSGPGVNSPPSAGGGGGSSGGGGGGGAYPPQPDFQPSQRTSA-- 799 R + +A G+ G G GA P P F+ R Sbjct: 2680 QRQRQRLRELLIRQQIQRNTLRQEKETAAAAAGAVGPPGSWGAEPSSPAFEQLSRGQTPF 2739 Query: 800 --------------SKLGALSLGSFNKPSSKDNLFGQSCLAALSTACQNMIASLGAPNLN 845 SKL LG + PS D L A S+ N +G + Sbjct: 2740 AGTQDKSSLVGLPPSKLSGPILGPGSFPSD-DRLSRPPPPATPSSMDVNSRQLVGG---S 2795 Query: 846 VTFNKKNPPEGKRKLSQNET---DGAAVAGNPGSDYFPGGTAPGAPGP-------GGPSG 895 F ++ P G L Q + + P PGP G P Sbjct: 2796 QAFYQRAPYPGSLPLQQQQQQLWQQQQATAATSMRFAMSARFPSTPGPELGRQALGSPLA 2855 Query: 896 TSSSGSKASGPPNPPAQGDGTSLSPNYTLESTSGNDGKPVSGGGGRGRGRRKRDSGHVSP 955 S+ G P P G + + ++ G G P G G R R S Sbjct: 2856 GISTRLPGPGEPVPGPAGPAQFIELRHNVQKGLGPGGTPFPGQGPPQRPRFYPVSE---- 2911 Query: 956 GTFFDKYSAAPD---SGGAPGVSPGQQQASGAAVGGSSAGETRGAPTPHEKALTSPSWGK 1012 D + AP+ G+ P + A A +S PTPH K T P+ Sbjct: 2912 ----DPHRLAPEGLRGLAVSGLPPQKPSAPPAPELNNSL-----HPTPHTKGPTLPT--- 2959 Query: 1013 GAELL 1017 G EL+ Sbjct: 2960 GLELV 2964 Score = 48.1 bits (113), Expect = 5e-05 Identities = 191/912 (20%), Positives = 281/912 (30%), Gaps = 148/912 (16%) Query: 145 SQPPFAEGYEHMAES--QGPESFGPQRPGNLPDFHSSGASSHAVPAPCLPLDQSPNRAAS 202 S PP + + + ES PE P P AS + P PL P Sbjct: 504 SPPPESSPFSPLEESPLSPPEESPPSPALETPLSPPPEASPLSPPFEESPLSPPPEE--- 560 Query: 203 FHGLPSSSGSDSHSLEPRRVTNQGAVDSLEYNYPGEAPSGHFDMFSPSDSEGQLPHYAAG 262 LP+S ++ L P + P P M P ++ P + Sbjct: 561 ---LPTSPPPEASRLSPPPEES-----------PMSPPPEESPMSPPPEASRLFPPFEES 606 Query: 263 RQVPGGAFPGASAMPRAAGMVGLSKMHAQPPQQQPQQQQQPQQQQQQHGVFFERFSGARK 322 P S P A+ + PP + P++ R S Sbjct: 607 PLSPPPEESPLSPPPEASRL--------SPPPEDSPMSPPPEESPMSPPPEVSRLS---P 655 Query: 323 MPV--GLEPSVGSRHPLMQPPQQAP--PPPQQQPPQQPPQQQPPPPPGLLVRQNSCPPAL 378 +PV L P PL PP+++P PPP+ PP+ P PP PA Sbjct: 656 LPVVSRLSPPP-EESPLSPPPEESPTSPPPEASRLSPPPEDSPTSPPP------EDSPAS 708 Query: 379 PRPQQGEAGTPSGGLQDGGPMLPSQHAQFEYPIHRLENRSMHPYSEPVFSMQHPPPQQAP 438 P P+ P + P+LP P + S P EP S + P +P Sbjct: 709 PPPEDSLMSLPL----EESPLLPLPEEPQLCPRSEGPHLSPRP-EEPHLSPRPEEPHLSP 763 Query: 439 NQRLQHF----DAPPYMNVAKRPRFDFPGSAGVDRCASWNGSMHNGAL--DNHLSPSAYP 492 H + P V + P P + G + +H + HLSP Sbjct: 764 QAEEPHLSPQPEEPCLCAVPEEPHLS-PQAEG-PHLSPQPEELHLSPQTEEPHLSP---- 817 Query: 493 GLPGE-FTPPVPDSFPSGPPLQHPAPDHQSLQQQQQQQQQQQQQQQQQQQQQQQQQQQQR 551 +P E P P+ P + P + + + ++ + ++ ++ Q Sbjct: 818 -VPEEPCLSPQPEESHLSPQSEEPCLSPRPEESHLSPELEKPPLSPRPEKPPEEPGQCPA 876 Query: 552 QNAALMIKQMASRNQQQRLRQPNLAQLGHP-----------GDVGQGGLVHG-------- 592 + + L +P L++ G P G+ L Sbjct: 877 PEELPLFPPPGEPSLSPLLGEPALSEPGEPPLSPLPEELPLSPSGEPSLSPQLMPPDPLP 936 Query: 593 ---------------GPVGGLAQPNFEREGGSTGAGRLGTFEQQAPHLAQESAWFSGPHP 637 P+G L P F +G S L + P A + P P Sbjct: 937 PPLSPIITAAAPPALSPLGELEYP-FGAKGDSDPESPLAAPILETPISPPPEANCTDPEP 995 Query: 638 PPGDLLPRRMGGSGLPADCGPHDPSLAPPPPPGGSGVLFRG--PLQEPMRMPGEGHVPAL 695 P +LP G + GP P L P PP S +L P P P + PAL Sbjct: 996 VPPMILPPSPG-----SPVGPASPILMEPLPPQCSPLLQHSLVPQNSP---PSQCSPPAL 1047 Query: 696 PSPGLQFGGSLGGLGQLQSPGAGVGLPSAASER--RPPPPDFATSALGGQPGFPFGAAGR 753 P L L +G++ L +E+ P P SA P P G Sbjct: 1048 P---LSVPSPLSPIGKVVGVSDEAELHEMETEKVSEPECPALEPSATSPLPS-PMGDLSC 1103 Query: 754 QSTPHSGPGVNSPPSAGGGGGSSGGGGGGGAYPPQPDFQPSQRTSASKLGALSLGSFNKP 813 + P P ++ G G G+ P +P P S K + L Sbjct: 1104 PA-PSPAPALDDFSGLGEDTAPLDGIDAPGSQP-EPGQTPGSLASELKGSPVLLDPEELA 1161 Query: 814 SSKDNLFGQSC--LAALSTACQNMIASLGAPNLNVTFNKKNPPEGKRKLSQNE----TDG 867 C A + C+ P V PP + NE + G Sbjct: 1162 PVTPMEVYPECKQTAGQGSPCEEQ----EEPRAPVA---PTPPTLIKSDIVNEISNLSQG 1214 Query: 868 AAVAGNPGSDYFPGGTAPGAPGPGGPSGTSSSGSKASGPPNPPAQGDGTSLSPNYTLEST 927 A A PGS+ G+P P G G S S PA+ +G+ +L T Sbjct: 1215 DASASFPGSE-----PLLGSPDPEG--GGSLSMELGVSTDVSPARDEGSLRLCTDSLPET 1267 Query: 928 SGN----DGKPVSGGGGRGRGRRKRDSGHVSPGTFFDKYSAAPDSGGAPGVSPGQQQASG 983 + G +SGG G R+R S + + G PG+++ G Sbjct: 1268 DDSLLCDAGTAISGGKAEGEKGRRRSSP-----------ARSRIKQGRSSSFPGRRRPRG 1316 Query: 984 AAVGGSSAGETR 995 A GG G R Sbjct: 1317 GAHGGRGRGRAR 1328 Score = 45.8 bits (107), Expect = 3e-04 Identities = 46/138 (33%), Positives = 62/138 (44%), Gaps = 13/138 (9%) Query: 518 DHQSLQQQQQQQQQQQQQQQQQQQQQQQQQQQQRQNAALMIKQMASRNQQQRL--RQPNL 575 D QQ++ + + +QQQQQQQQQQQQQ+ +A L + S +Q RL + P Sbjct: 3579 DQVRKQQKEHTNLMAEYRNKQQQQQQQQQQQQQQHSAVLAL----SPSQSPRLLTKLPGQ 3634 Query: 576 AQLGHPGDVGQGGLVHGGPVGGL-AQPNFEREGGSTGAGRLGT--FEQQAPHLAQESAWF 632 GH QG GG GGL P G G L T +QQ + + Sbjct: 3635 LLPGHGLQPPQG--PPGGQAGGLRLTPGGMALPGQPGGPFLNTALAQQQQQQHSGGAGSL 3692 Query: 633 SGPHPP--PGDLLPRRMG 648 +GP PG+L R +G Sbjct: 3693 AGPSGGFFPGNLALRSLG 3710 Score = 44.7 bits (104), Expect = 6e-04 Identities = 87/426 (20%), Positives = 140/426 (32%), Gaps = 80/426 (18%) Query: 160 QGPESFGPQRPGNLPDFHSSGASSHAVPAPCLPLDQSPNRAASFHGLPSSSGSDSHSLEP 219 + P S P+ P +S S P PL ++ + + P S + L P Sbjct: 446 ESPLSPPPEESPTSPPPEASRLSPPPEELPASPLPEALHLSRPLEESPLSPPPEESPLSP 505 Query: 220 RRVTNQ-GAVDSLEYNYPGEAPSG---HFDMFSPSDSEGQLPHYAAGRQVPGGAFPGASA 275 ++ ++ + P E+P + P ++ P + P S Sbjct: 506 PPESSPFSPLEESPLSPPEESPPSPALETPLSPPPEASPLSPPFEESPLSPPPEELPTSP 565 Query: 276 MPRAAGMVGLSKMHAQPPQQQPQQ---QQQPQQQQQQHGVFFERFSGARKMPVGLE---- 328 P A+ + + PP++ P ++ P + F F + P E Sbjct: 566 PPEASRL-------SPPPEESPMSPPPEESPMSPPPEASRLFPPFEESPLSPPPEESPLS 618 Query: 329 -PSVGSR-------HPLMQPPQQAP--------------------PPPQQQPPQQPPQQQ 360 P SR P+ PP+++P PPP++ P PP++ Sbjct: 619 PPPEASRLSPPPEDSPMSPPPEESPMSPPPEVSRLSPLPVVSRLSPPPEESPLSPPPEES 678 Query: 361 PPPPPGLLVRQNSCP---PALPRPQQGEAGTPSGGLQDGGPMLPSQHAQFEYPIHRL-EN 416 P PP R + P P P P+ A P +D LP + E P+ L E Sbjct: 679 PTSPPPEASRLSPPPEDSPTSPPPEDSPASPPP---EDSLMSLPLE----ESPLLPLPEE 731 Query: 417 RSMHPYSE-PVFSMQHPPPQQAPNQRLQHFDAPPYMNVAKRPRFDFPGSAGVDRCASWNG 475 + P SE P S + P +P H +P P+ + P V Sbjct: 732 PQLCPRSEGPHLSPRPEEPHLSPRPEEPHL-SPQAEEPHLSPQPEEPCLCAVPE------ 784 Query: 476 SMHNGALDNHLSPSAYPGLPGEFTPPVPDSFPSGP----PLQHPAPDHQSLQQQQQQQQQ 531 + HLSP A G P P+ P P P P+ L Q ++ Sbjct: 785 -------EPHLSPQA----EGPHLSPQPEELHLSPQTEEPHLSPVPEEPCLSPQPEESHL 833 Query: 532 QQQQQQ 537 Q ++ Sbjct: 834 SPQSEE 839 Score = 42.7 bits (99), Expect = 0.002 Identities = 53/223 (23%), Positives = 80/223 (35%), Gaps = 27/223 (12%) Query: 294 QQQPQQQQQPQQQQQQHGVFFERFSGARKMPVGLEPSVGSRHPLMQPPQQAPPPPQQQPP 353 Q QP+ Q ++ G K V LEP + + PL + PPP++ P Sbjct: 393 QGQPKGGHVTSMQPKEPGPLQCEAKPLGKAGVQLEPQLEA--PLNEE-MPLLPPPEESPL 449 Query: 354 QQPPQQQPPPPPGLLVRQNSCPPALPRPQQGEAGTPSGGLQDGGPMLPSQHAQFEYPIHR 413 PP++ P PP R + P LP EA S L++ P + + P Sbjct: 450 SPPPEESPTSPPPEASRLSPPPEELPASPLPEALHLSRPLEESPLSPPPEESPLSPP--- 506 Query: 414 LENRSMHPYSEPVFSMQHPPPQQAPNQRLQ-HFDAPPYMNVAKRPRFDFPGSAGVDRCAS 472 E+ P E S PP + P+ L+ PP + P + P S + Sbjct: 507 PESSPFSPLEESPLS---PPEESPPSPALETPLSPPPEASPLSPPFEESPLSPPPEEL-- 561 Query: 473 WNGSMHNGALDNHLSPSAYPGLPGEFTPPVPDSFPSGPPLQHP 515 P++ P +PP +S S PP + P Sbjct: 562 ---------------PTSPPPEASRLSPPPEESPMSPPPEESP 589 Score = 35.0 bits (79), Expect = 0.48 Identities = 50/161 (31%), Positives = 63/161 (39%), Gaps = 21/161 (13%) Query: 285 LSKMHAQPPQQQPQQQQQPQQQQQQHGVFFERF-SGARKMP-VGLEPSV-GSRHPLMQPP 341 L K Q QP QQQ QQQQQQH + + A +P G PS+ GS+ L Sbjct: 3260 LQKKQQLSAQLQPAQQQ--QQQQQQHSLLSAPGPAQAMSLPHEGSSPSLAGSQQQLSLGL 3317 Query: 342 QQAPPPPQQQPPQQPPQQQPPPPPGLLVRQNSCPPALPRPQQGEAGTPSGGLQDGGPMLP 401 A P QP P PP ++Q P QG + G Q G ++P Sbjct: 3318 AGARQPGLPQP------LMPTQPPAHALQQRLAPSMAMVSNQGHMLSGQHGGQAG--LVP 3369 Query: 402 SQHAQFEYPIHRLENRSMHPYSEPVFSMQHPPPQQAPNQRL 442 Q +Q P+ S P SM P Q A Q+L Sbjct: 3370 QQSSQ---PV-----LSQKPMGTMPPSMCMKPQQLAMQQQL 3402 Score = 33.9 bits (76), Expect = 1.1 Identities = 15/37 (40%), Positives = 26/37 (70%) Query: 520 QSLQQQQQQQQQQQQQQQQQQQQQQQQQQQQRQNAAL 556 + L + ++++ Q++QQ Q Q QQQQQQQ+Q++ L Sbjct: 3250 EDLLEHEKKELQKKQQLSAQLQPAQQQQQQQQQHSLL 3286 Score = 33.9 bits (76), Expect = 1.1 Identities = 14/35 (40%), Positives = 20/35 (57%) Query: 328 EPSVGSRHPLMQPPQQAPPPPQQQPPQQPPQQQPP 362 EP V S PL P+ A P P+ +PP++ +PP Sbjct: 4943 EPPVPSPLPLASSPESARPKPRARPPEEGEDSRPP 4977 Score = 33.5 bits (75), Expect = 1.4 Identities = 15/29 (51%), Positives = 20/29 (68%) Query: 518 DHQSLQQQQQQQQQQQQQQQQQQQQQQQQ 546 +H+ + Q++QQ Q Q QQQQQQQQQ Sbjct: 3254 EHEKKELQKKQQLSAQLQPAQQQQQQQQQ 3282 Score = 33.1 bits (74), Expect = 1.8 Identities = 27/75 (36%), Positives = 31/75 (41%), Gaps = 9/75 (12%) Query: 512 LQHPAPDHQSLQQQQQQQQQQQQQQQQQQQQQQQQQQQQRQNAAL----MIKQMASRNQQ 567 L+H + Q QQ Q Q QQQQQQQQQ Q +L +A QQ Sbjct: 3253 LEHEKKELQKKQQLSAQLQPAQQQQQQQQQHSLLSAPGPAQAMSLPHEGSSPSLAGSQQQ 3312 Query: 568 QRL-----RQPNLAQ 577 L RQP L Q Sbjct: 3313 LSLGLAGARQPGLPQ 3327 Score = 33.1 bits (74), Expect = 1.8 Identities = 39/130 (30%), Positives = 45/130 (34%), Gaps = 25/130 (19%) Query: 236 PGEAPSGHFDMFSPS--DSEGQLPHYAAGRQVPGGAFPGASAMPRAAGMVGLSKMHAQPP 293 P +A S + SPS S+ QL AG + PG P M QPP Sbjct: 3291 PAQAMSLPHEGSSPSLAGSQQQLSLGLAGARQPGLPQP---------------LMPTQPP 3335 Query: 294 QQQPQQQQQPQQ---QQQQHGVFFERFSGARKMPVGLEPSVGSRHPLMQPPQQAPPPPQQ 350 QQ+ P Q H SG GL P S+ L Q P PP Sbjct: 3336 AHALQQRLAPSMAMVSNQGH-----MLSGQHGGQAGLVPQQSSQPVLSQKPMGTMPPSMC 3390 Query: 351 QPPQQPPQQQ 360 PQQ QQ Sbjct: 3391 MKPQQLAMQQ 3400 Score = 32.7 bits (73), Expect = 2.4 Identities = 104/453 (22%), Positives = 143/453 (31%), Gaps = 81/453 (17%) Query: 96 QPHHGHPGSHHPHQHHPHFGGN--FGGPDPGASCLHGGRLLGYGGAAGGLGSQPPFAEGY 153 +P PG PH + HFG G P + G G G S E Y Sbjct: 2548 KPPVPQPGLPPPHGINSHFGPGPTLGKPQSTNYTVATGNFHPSGSPLGP--SSGSTGESY 2605 Query: 154 EHMAESQGPESFGPQRP-GNLPDFHSSGASSHAVPAPCLPLDQSPNRA-------ASFHG 205 ++ + P P P G+LP + S GAS + + + P A G Sbjct: 2606 G-LSPLRPPSVLPPPAPDGSLP-YLSHGASQRSGITSPVEKREDPGTGMGSSLATAELPG 2663 Query: 206 L--PSSSGSDSHSLEPRRVTNQ-------GAVDSLEYNYPGEAPSGHFDMFSPSDSEGQL 256 P SG LE +R + + E + P S G Sbjct: 2664 TQDPGMSGLSQTELEKQRQRQRLRELLIRQQIQRNTLRQEKETAAAAAGAVGPPGSWGAE 2723 Query: 257 PHYAAGRQVPGGAFPGASAMPRAAGMVGLSKMHAQPPQQQPQQQQQPQQQQQQHGVFFER 316 P A Q+ G P A +++ +VGL P P + + Sbjct: 2724 PSSPAFEQLSRGQTPFAGTQDKSS-LVGLPPSKLSGPILGPGSFPSDDRLSRPPPP---- 2778 Query: 317 FSGARKMPVGLEPSVGSRHPLMQ-PPQQAPPPPQQQPPQQPPQQQPPPPPGLLVRQNSCP 375 + M V VG Q P P QQQ Q QQQ + ++ Sbjct: 2779 -ATPSSMDVNSRQLVGGSQAFYQRAPYPGSLPLQQQQQQLWQQQQATAATSMRFAMSARF 2837 Query: 376 PALPRPQQGE--AGTPSGGLQ-----DGGPML-PSQHAQFEYPIHRLENRSMHPYSEPVF 427 P+ P P+ G G+P G+ G P+ P+ AQF H ++ + + P P F Sbjct: 2838 PSTPGPELGRQALGSPLAGISTRLPGPGEPVPGPAGPAQFIELRHNVQ-KGLGPGGTP-F 2895 Query: 428 SMQHPPPQQAPNQRLQHFDAPPYMNVAKRPRFDFPGSAGVDRCASWNGSMHNGALDNHLS 487 Q PP +RPRF +P S R L+ Sbjct: 2896 PGQGPP---------------------QRPRF-YPVSEDPHR----------------LA 2917 Query: 488 PSAYPGLPGEFTPPVPDSFPSGPPLQ---HPAP 517 P GL PP S P P L HP P Sbjct: 2918 PEGLRGLAVSGLPPQKPSAPPAPELNNSLHPTP 2950 Score = 30.8 bits (68), Expect = 9.0 Identities = 39/139 (28%), Positives = 47/139 (33%), Gaps = 30/139 (21%) Query: 637 PPPGDL----LPRRMGGSG----LPADCGPHDPSLAPPPPPGGSGVLFRGPLQEPMRMPG 688 PPP +L LP + S P P + L+PPP L PL P P Sbjct: 469 PPPEELPASPLPEALHLSRPLEESPLSPPPEESPLSPPPESSPFSPLEESPLSPPEESP- 527 Query: 689 EGHVPALPSPGLQFGGSLGGLGQLQSPGAGVGLPSAASERRPPPPDFATSALGGQPGFPF 748 PSP L+ S SP P S PPP + TS P Sbjct: 528 -------PSPALETPLSPPPEASPLSP------PFEESPLSPPPEELPTS--------PP 566 Query: 749 GAAGRQSTPHSGPGVNSPP 767 A R S P ++ PP Sbjct: 567 PEASRLSPPPEESPMSPPP 585 >gi|110735435 collagen, type V, alpha 3 preproprotein [Homo sapiens] Length = 1745 Score = 91.3 bits (225), Expect = 6e-18 Identities = 251/1097 (22%), Positives = 344/1097 (31%), Gaps = 241/1097 (21%) Query: 138 GAAGGLGSQPPFAEG--YEHMAESQGPESF-GPQRPGNLPDFHSSGASSHAVPAPCLPLD 194 G G G +G +E + GP+ GP P P F P D Sbjct: 373 GEKGAKGEPAVIEKGQQFEGPPGAPGPQGVVGPSGPPGPPGF---------------PGD 417 Query: 195 QSPNRAASFHGLPSSSGSDSHSLEPRRVTNQGAVDSLEYNYPGEAPSGHFDMFSPSDSEG 254 P A GLP G D P G V + + + G + G F + ++ Sbjct: 418 PGPPGPA---GLPGIPGIDGIRGPP------GTVIMMPFQFAGGSFKGPPVSFQQAQAQA 468 Query: 255 QLPHYAAGRQVPGGAFPGASAMPRAAGMVGLSKMHAQPPQQQPQQQQQPQQQQQQHG--- 311 L + P PG + G VGL ++ + Q P+ Q HG Sbjct: 469 VLQQTQLSMKGP----PGPVGLTGRPGPVGLPGHPGLKGEEGAEGPQGPRGLQGPHGPPG 524 Query: 312 ----VFFERFSGARKMP--------------VGLEPSVGSRHPLMQPPQQAPPPPQQQ-- 351 + GAR +P GL G R Q PP + Sbjct: 525 RVGKMGRPGADGARGLPGDTGPKGDRGFDGLPGLPGEKGQRGDFGHVGQPGPPGEDGERG 584 Query: 352 ---PPQQPPQQQPPPPPGLLVRQNSCPPALPRPQQGEAGTPSGGLQDGGPMLPSQHAQFE 408 PP Q P P GLL PR G G P DG P Sbjct: 585 AEGPPGPTGQAGEPGPRGLLG---------PRGSPGPTGRPGVTGIDGAPGAKG------ 629 Query: 409 YPIHRLENRSMHPYSEPVFSMQHPPPQQAPNQRLQHFDAPPYMNVAKRPRFDFPGSAGVD 468 ++ P EP PP Q N Q P + + PG+ G+ Sbjct: 630 ---------NVGPPGEP------GPPGQQGNHGSQGLPGPQGL-IGTPGEKGPPGNPGIP 673 Query: 469 RCASWNGSMHNGALDNHLSPSAYPGLPGEFTPPVPDSFPSGPPLQHPAPDHQSLQQQQQQ 528 +G + + + G PG PP +P GP ++ LQ ++ + Sbjct: 674 GLPGSDGPLGHPGHEGPTGEKGAQGPPGSAGPP---GYP-GPRGVKGTSGNRGLQGEKGE 729 Query: 529 Q----------------QQQQQQQQQQQQQQQQQQQQQRQNAALMIKQMASRNQQQRLRQ 572 + Q + + + + + + A S ++ +L Sbjct: 730 KGEDGFPGFKGDVGLKGDQGKPGAPGPRGEDGPEGPKGQAGQAGEEGPPGSAGEKGKLGV 789 Query: 573 PNLAQLGHPGDVG-QGGLVHGGPVGGLA---------QPNFEREGGSTGA----GRLGTF 618 P L G+PG G +G + GP+G + QP E E G G+ G+ G Sbjct: 790 PGLP--GYPGRPGPKGSIGFPGPLGPIGEKGKSGKTGQPGLEGERGPPGSRGERGQPGAT 847 Query: 619 EQQAPH--LAQESAWFSGPHPPPGDLLPRRMGGSGLPADCGP--HDPSLAPPPPPGGSGV 674 Q P + Q+ A P P LP G G P GP H P PG G Sbjct: 848 GQPGPKGDVGQDGA----PGIPGEKGLPGLQGPPGFPGPKGPPGHQGKDGRPGHPGQRGE 903 Query: 675 L-FRGPLQEPMRMPGEGHVPALPSPGLQFGGSLGGLGQLQSPGAGVGLPSAASERRPPPP 733 L F+G P G L G G +G LG+ PG P E+ P Sbjct: 904 LGFQGQTGPP------GPAGVLGPQGKT--GEVGPLGERGPPGP----PGPPGEQGLPGL 951 Query: 734 DFATSALG--GQPGFPFGAAGRQST-----PHSGPGVNSPPSAGGGGGSSGGGGGGGAYP 786 + A G G PG P G G P GPG P G G G G G+ Sbjct: 952 EGREGAKGELGPPG-PLGKEGPAGLRGFPGPKGGPGDPGPTGLKGDKGPPGPVGANGS-- 1008 Query: 787 PQPDFQPSQRTSASKLGALSLGSFNKPSSKDNLFGQSCLAALSTACQNMIASLGAPNLNV 846 P +R G + L GQS +G Sbjct: 1009 ------PGERGPLGPAGGIGLP------------GQS----------GSEGPVGPAGKKG 1040 Query: 847 TFNKKNPPEGKRKLSQNETDGAAVAGNPGSDYFPGGTAP-GAPGPGGPSGTSSSGSKASG 905 + ++ PP G G D PG P G PG GPSG Sbjct: 1041 SRGERGPP-----------------GPTGKDGIPGPLGPLGPPGAAGPSGEEGDKGDVGA 1083 Query: 906 PPNPPAQGDGTSLSP--NYTLESTSGNDGKPVSGGGGRGRGRRKRDSGHVSPGTFFDKYS 963 P + ++GD P + +G+ G P + G RG PG F K Sbjct: 1084 PGHKGSKGDKGDAGPPGQPGIRGPAGHPGPPGADGAQGRRG---------PPGLFGQK-- 1132 Query: 964 AAPDSG--------GAPGVS--PGQQQASGAAVGGSSAGETRGAPTPHEKALTSPSWGKG 1013 D G G PG+ PG G VG + GAP P + P+ +G Sbjct: 1133 --GDDGVRGFVGVIGPPGLQGLPGPPGEKGE-VGDVGSMGPHGAPGP--RGPQGPTGSEG 1187 Query: 1014 AELLLGD--QPDLIGSLDGGAKSDSSSPNVGEFASDEVSTSYANEDEVSSSSDNPQALVK 1071 L G QP +G + G + D+ P G + + + E S + A Sbjct: 1188 TPGLPGGVGQPGAVG--EKGERGDAGDP--GPPGAPGIPGPKGDIGEKGDSGPSGAAGPP 1243 Query: 1072 ASRSPLVTGSPK--LPPRGVGAGEHGPKAPPPALGLGIMSNSTSTPDSYGGGGGP---GH 1126 + P K + P G+ G+ GP P G+ P GG G P G Sbjct: 1244 GKKGPPGEDGAKGSVGPTGL-PGDLGPPGDPGVSGIDGSPGEKGDPGDVGGPGPPGASGE 1302 Query: 1127 PGTPGLEQVRTPTSSSG 1143 PG PG R P+ G Sbjct: 1303 PGAPGPPGKRGPSGHMG 1319 Score = 91.3 bits (225), Expect = 6e-18 Identities = 300/1198 (25%), Positives = 366/1198 (30%), Gaps = 241/1198 (20%) Query: 43 GPPGPVD----PAMSALGEPPILGMNMEPYGFHARGHSELHAGGLQAQPVHGFFGGQQPH 98 GPPGP P + + PP + M P+ F QAQ Q Sbjct: 419 GPPGPAGLPGIPGIDGIRGPPGTVIMM-PFQFAGGSFKGPPVSFQQAQAQAVLQQTQLSM 477 Query: 99 HGHPGSHHPHQHHPHFGGNFGGPDPGASCLHGGRLLGYGGAAGGLGSQPPFAEGYEHMAE 158 G PG G G P P L G+ G G G AEG + Sbjct: 478 KGPPGPV----------GLTGRPGPVG-------LPGHPGLKGEEG-----AEGPQGPRG 515 Query: 159 SQGPESFGPQRPGNLPDFHSSGASSHAVPAPCLPLDQSPNRAASFHGLPSSSGSDSHSLE 218 QGP GP PG + GA A LP D P F GLP G + Sbjct: 516 LQGPH--GP--PGRVGKMGRPGADG----ARGLPGDTGPKGDRGFDGLPGLPGEKGQRGD 567 Query: 219 PRRVTNQGAVDSLEYNYPGEAPSGHFDMFSPSDSEGQLPHYAAGRQVPGGAFPGASAMPR 278 V G PGE G P GQ AG P G G P Sbjct: 568 FGHVGQPGP--------PGE--DGERGAEGPPGPTGQ-----AGEPGPRGLL-GPRGSPG 611 Query: 279 AAGMVGLSKMHAQPPQQQ---PQQQQQPQQQQQQHGVFFERFSGARKMPVGLEPSVGSRH 335 G G++ + P + P + P QQ HG S P GL + G + Sbjct: 612 PTGRPGVTGIDGAPGAKGNVGPPGEPGPPGQQGNHG------SQGLPGPQGLIGTPGEKG 665 Query: 336 PLMQPPQQAPP--------PPQQQPPQQPPQQQPPPPPGLLVRQNSCPPALPRPQ----- 382 P P P P + P + Q PP G PP P P+ Sbjct: 666 PPGNPGIPGLPGSDGPLGHPGHEGPTGEKGAQGPPGSAG--------PPGYPGPRGVKGT 717 Query: 383 ------QGEAGTPSGGLQDGGPM------LPSQHAQFEYPIHRLENRSMHPYSEPVFSMQ 430 QGE G +DG P L + P R E+ P + + + Sbjct: 718 SGNRGLQGEKGEKG---EDGFPGFKGDVGLKGDQGKPGAPGPRGEDGPEGPKGQAGQAGE 774 Query: 431 HPPPQQAPNQRLQHFDAPPYMNVAKRPR--FDFPGSAGVDRCASWNGSMHNGALDNHLSP 488 PP A + P P+ FPG G +G L+ P Sbjct: 775 EGPPGSAGEKGKLGVPGLPGYPGRPGPKGSIGFPGPLGPIGEKGKSGKTGQPGLEGERGP 834 Query: 489 SAYPGLPGEFTPP--VPDSFPSGPPLQHPAPD---HQSLQQQQQQQQQQQQQQQQQQQQQ 543 PG GE P P G Q AP + L Q + Q + Sbjct: 835 ---PGSRGERGQPGATGQPGPKGDVGQDGAPGIPGEKGLPGLQGPPGFPGPKGPPGHQGK 891 Query: 544 QQQQQQQRQNAALMIKQMASRNQQQRLRQPNLAQLGHPGDVGQGGLVHG-GPVGGLAQPN 602 + Q L + + P + G G +G+ G GP G P Sbjct: 892 DGRPGHPGQRGELGFQGQTGPPGPAGVLGPQ-GKTGEVGPLGERGPPGPPGPPGEQGLPG 950 Query: 603 FE-REGGSTGAGRLGTFEQQAPHLAQESAWFSGPHPPPGDLLPRRMGGSGLPADCGPHDP 661 E REG G G ++ P + F GP PGD G +GL D GP Sbjct: 951 LEGREGAKGELGPPGPLGKEGPAGLRG---FPGPKGGPGD-----PGPTGLKGDKGP--- 999 Query: 662 SLAPPPPPGGSGVLFRGPLQEPMRMPGEGHVPALPSPGLQFGGSLGGLGQLQSPGAGVGL 721 P P G +G PGE P P+ G+ G G G P G Sbjct: 1000 ----PGPVGANG------------SPGE-RGPLGPAGGIGLPGQSGSEG----PVGPAGK 1038 Query: 722 PSAASERRPPPP---DFATSALGGQPGFPFGAAGRQSTPHSGPGVNSPPSAGGGGGSSGG 778 + ER PP P D LG P P GAAG P G A G GS G Sbjct: 1039 KGSRGERGPPGPTGKDGIPGPLG--PLGPPGAAG----PSGEEGDKGDVGAPGHKGSKGD 1092 Query: 779 GGGGGAYPPQPDFQPSQRTSASKLGALSLGSFNKPSSKDNLFGQSCLAALSTACQNMIAS 838 G G P QP R A G LFGQ + + Sbjct: 1093 KGDAG-----PPGQPGIRGPAGHPGPPGADGAQGRRGPPGLFGQKG----DDGVRGFVGV 1143 Query: 839 LGAPNLNVTFNKKNPPEGKRKLS----------------QNETDGAAVAGNPGSDYFPGG 882 +G P L PP K ++ Q T G PG PG Sbjct: 1144 IGPPGLQ---GLPGPPGEKGEVGDVGSMGPHGAPGPRGPQGPTGSEGTPGLPGGVGQPGA 1200 Query: 883 TA-------------PGAPGPGGPSGT-----SSSGSKASGPPN---PPAQGDGTSLSPN 921 PGAPG GP G S S A+GPP PP + DG S Sbjct: 1201 VGEKGERGDAGDPGPPGAPGIPGPKGDIGEKGDSGPSGAAGPPGKKGPPGE-DGAKGSVG 1259 Query: 922 YTLESTSGNDGKPVSGG--GGRGRGRRKRDSGHVS-PGTFFDKYSAAPDSGGAPGVSPGQ 978 T G+ G P G G G K D G V PG A GAPG PG+ Sbjct: 1260 PT--GLPGDLGPPGDPGVSGIDGSPGEKGDPGDVGGPGP-----PGASGEPGAPG-PPGK 1311 Query: 979 QQASGAAVGGSSAGE--TRGAPTPH-EKALTSPSWGKGAELLLGDQ-----------PDL 1024 + SG GE +G P P T P +G +G + P L Sbjct: 1312 RGPSGHMGREGREGEKGAKGEPGPDGPPGRTGPMGARGPPGRVGPEGLRGIPGPVGEPGL 1371 Query: 1025 IGSLDG----GAKSDSSSPNV-------GEFASDEVSTSYANEDEVSSSSDNPQALVKAS 1073 +G+ G S P + GE + E D Q L Sbjct: 1372 LGAPGQMGPPGPLGPSGLPGLKGDTGPKGEKGHIGLIGLIGPPGEAGEKGD--QGLPGVQ 1429 Query: 1074 RSPLVTGSPKLPPRGVGAGEHGPKAPPPALGLGIMSNSTSTPDSYGGGGGPGHPGTPG 1131 P G P PP +G+ H PP G S +P S G G G G PG Sbjct: 1430 GPPGPKGDPG-PPGPIGSLGH--PGPPGVAGPLGQKGSKGSPGSMGPRGDTGPAGPPG 1484 Score = 82.8 bits (203), Expect = 2e-15 Identities = 184/730 (25%), Positives = 223/730 (30%), Gaps = 192/730 (26%) Query: 488 PSAYPGLPGEFTPPVPDSFPSGPPLQ--HPAPDHQSLQQQQQQQQQQQQQQQQQQQQQQQ 545 P PG PG+ PP P P P + P + Q + QQ Q Q Sbjct: 408 PPGPPGFPGDPGPPGPAGLPGIPGIDGIRGPPGTVIMMPFQFAGGSFKGPPVSFQQAQAQ 467 Query: 546 QQQQQRQNAALMIKQMASRNQQQRLRQPNLAQLGHPGDVGQGGLVHGGPVGGLAQPNFER 605 QQ Q L+ G PG VG G GPVG P + Sbjct: 468 AVLQQTQ----------------------LSMKGPPGPVGLTG--RPGPVGLPGHPGLKG 503 Query: 606 EGGSTGAGRLGTFEQQAPHLAQESAWFSGPHPPPGDL----LPRRMGGSGLPADCGPHDP 661 E G+ G Q P Q GPH PPG + P G GLP D G Sbjct: 504 EEGAEG--------PQGPRGLQ------GPHGPPGRVGKMGRPGADGARGLPGDTG---- 545 Query: 662 SLAPPPPPGGSGVLFRGPLQEPMRMPGEGHVPALPSPGLQFGGSLGGLGQLQSPGAGVGL 721 P G G F G +P LP G G G + PG Sbjct: 546 ------PKGDRG--FDG-------------LPGLPGE----KGQRGDFGHVGQPGP---- 576 Query: 722 PSAASERRPPPPDFATSALGGQPGFPFGAAGRQSTPHSGPGVNSPPSAGGGGGSSGGGGG 781 P ER P T G+PG P G G P PG P G G+ G G Sbjct: 577 PGEDGERGAEGPPGPTGQ-AGEPG-PRGLLG----PRGSPGPTGRPGVTGIDGAPGAKGN 630 Query: 782 GGAYPPQPDFQPSQRTSASKLGALSLGSFNKPSSKDNLFGQSCLAALSTACQNMIASLGA 841 G PP P Q+ + GS P G Sbjct: 631 VG--PPGEPGPPGQQGNH--------GSQGLP--------------------------GP 654 Query: 842 PNLNVTFNKKNPPEGKRKLSQNETDGAAVAGNPGSDYFPGGTAP-GAPGPGGPSGTSSSG 900 L T +K PP GNPG PG P G PG GP+G + Sbjct: 655 QGLIGTPGEKGPP-----------------GNPGIPGLPGSDGPLGHPGHEGPTGEKGAQ 697 Query: 901 SK--ASGPPNPPAQGDGTSLSPNYTLESTSGNDGKPVSGGGGRGRGRRKRDSGHVSPGTF 958 ++GPP P S N L+ G G+ G +G K D G PG Sbjct: 698 GPPGSAGPPGYPGPRGVKGTSGNRGLQGEKGEKGED-GFPGFKGDVGLKGDQG--KPG-- 752 Query: 959 FDKYSAAPDSGGAPGVSPGQQQASGAAVGG--SSAGETRGAPTPHEKALTSPSWGKGAEL 1016 AP G G + QA A G SAGE P KG+ Sbjct: 753 ------APGPRGEDGPEGPKGQAGQAGEEGPPGSAGEKGKLGVPGLPGYPGRPGPKGS-- 804 Query: 1017 LLGDQPDLIGSLDGGAKSDSSSPNVGEFASDEVSTSYANEDEVSSSSDNPQALVKASRSP 1076 +G P +G + KS + E + ++ P+ V +P Sbjct: 805 -IG-FPGPLGPIGEKGKSGKTGQPGLEGERGPPGSRGERGQPGATGQPGPKGDVGQDGAP 862 Query: 1077 LVTGSPKLPPRGVGAGEHGPKAPPPALGLGIMSNSTSTPDSYGGGGGPGHPGTPGLEQVR 1136 + G LP G GPK P P G G PGHPG G + Sbjct: 863 GIPGEKGLPGLQGPPGFPGPKGP---------------PGHQGKDGRPGHPGQRGELGFQ 907 Query: 1137 TPTSSSGAPPPDEIHPLEILQAQIQLQRQQFSISEDQPLGLKG-----GKKGECAV-GAS 1190 T G P + P Q E PLG +G G GE + G Sbjct: 908 GQTGPPG--PAGVLGP-------------QGKTGEVGPLGERGPPGPPGPPGEQGLPGLE 952 Query: 1191 GAQNGDSELG 1200 G + ELG Sbjct: 953 GREGAKGELG 962 Score = 61.6 bits (148), Expect = 5e-09 Identities = 168/687 (24%), Positives = 205/687 (29%), Gaps = 147/687 (21%) Query: 579 GHPGDVGQGGLVHGGPVGGLAQPNFEREGGSTGA-GRLGTFEQQAPHLAQESAWFSGPHP 637 G PG+ GQ G G VG P + E G+ G G G + P GP Sbjct: 557 GLPGEKGQRG--DFGHVGQPGPPGEDGERGAEGPPGPTGQAGEPGPR------GLLGPRG 608 Query: 638 PPGDL-LPRRMGGSGLPADCGPHDPSLAPPPPPGGSGVLFRGPLQEPMRM---PGEGHVP 693 PG P G G P G P P PPG G L P + PGE P Sbjct: 609 SPGPTGRPGVTGIDGAPGAKGNVGPP-GEPGPPGQQGNHGSQGLPGPQGLIGTPGEKGPP 667 Query: 694 ALPS-PGLQFGGSLGGLGQLQSPG-----AGVGLPSAASERRPPPPDFATSALG------ 741 P PGL GS G LG G G P +A P P G Sbjct: 668 GNPGIPGLP--GSDGPLGHPGHEGPTGEKGAQGPPGSAGPPGYPGPRGVKGTSGNRGLQG 725 Query: 742 -----GQPGFP-----FGAAGRQSTPHSGPGVNSPPSAGGGGGSSGGGGGGGAYPPQPDF 791 G+ GFP G G Q P G P G G G G G P Sbjct: 726 EKGEKGEDGFPGFKGDVGLKGDQGKP----GAPGPRGEDGPEGPKGQAGQAGEEGP---- 777 Query: 792 QPSQRTSASKLGALSLGSF-NKPSSKDNLFGQSCLAALSTACQNMIASLGAPNLNVTFNK 850 P KLG L + +P K ++ L + ++ G P L + Sbjct: 778 -PGSAGEKGKLGVPGLPGYPGRPGPKGSIGFPGPLGPIGEKGKS--GKTGQPGLE---GE 831 Query: 851 KNPPEGKRKLSQNETDGA----------AVAGNPGSDYFPGGTAP-GAPGPGGPSGTSSS 899 + PP + + Q G G PG PG P G PGP GP G Sbjct: 832 RGPPGSRGERGQPGATGQPGPKGDVGQDGAPGIPGEKGLPGLQGPPGFPGPKGPPGHQGK 891 Query: 900 GSKAS-----------------------------------------GPPNPPA------- 911 + GPP PP Sbjct: 892 DGRPGHPGQRGELGFQGQTGPPGPAGVLGPQGKTGEVGPLGERGPPGPPGPPGEQGLPGL 951 Query: 912 ---QGDGTSLSPNYTL--ESTSGNDG--KPVSGGGGRGRGRRKRDSGHVSP----GTFFD 960 +G L P L E +G G P G G G K D G P G+ + Sbjct: 952 EGREGAKGELGPPGPLGKEGPAGLRGFPGPKGGPGDPGPTGLKGDKGPPGPVGANGSPGE 1011 Query: 961 KYSAAPDSG-GAPGVSPGQQQASGAAVGGSSAGETRGAPTPHEK-------ALTSPSWGK 1012 + P G G PG S G + G A S GE RG P P K P Sbjct: 1012 RGPLGPAGGIGLPGQS-GSEGPVGPAGKKGSRGE-RGPPGPTGKDGIPGPLGPLGPPGAA 1069 Query: 1013 GAELLLGDQPDLIGSLDGGAKSDS------SSPNV-------GEFASDEVSTSYANEDEV 1059 G GD+ D+ G+K D P + G +D Sbjct: 1070 GPSGEEGDKGDVGAPGHKGSKGDKGDAGPPGQPGIRGPAGHPGPPGADGAQGRRGPPGLF 1129 Query: 1060 SSSSDN-PQALVKASRSPLVTGSPKLPPRGVGAGEHGPKAPPPALGLGIMSNSTSTPDSY 1118 D+ + V P + G P P G+ G P A G T + + Sbjct: 1130 GQKGDDGVRGFVGVIGPPGLQGLPGPPGEKGEVGDVGSMGPHGAPGPRGPQGPTGSEGTP 1189 Query: 1119 GGGGGPGHPGTPGLEQVRTPTSSSGAP 1145 G GG G PG G + R G P Sbjct: 1190 GLPGGVGQPGAVGEKGERGDAGDPGPP 1216 Score = 56.2 bits (134), Expect = 2e-07 Identities = 79/238 (33%), Positives = 92/238 (38%), Gaps = 47/238 (19%) Query: 579 GHPGDVGQGGLVHG-GPVGGLAQPNFEREGGSTG-AGRLGTFEQQAPHLAQESAWFSGPH 636 G PG+ G G V G GP G +P G G +G +G ++ A+ GP Sbjct: 1280 GSPGEKGDPGDVGGPGPPGASGEPGAPGPPGKRGPSGHMGREGREGEKGAKGEP---GPD 1336 Query: 637 PPPGDLLPRRMGGSGLPADCGPHDPSLAPPPPPGGSGVLFRGPLQEPMRMPGEGHVPALP 696 PPG P MG G P GP L P P G L P Q M PG P P Sbjct: 1337 GPPGRTGP--MGARGPPGRVGPE--GLRGIPGPVGEPGLLGAPGQ--MGPPG----PLGP 1386 Query: 697 S--PGLQFG-------GSLGGLGQLQSPGAG-----VGLPSAASERRPPPPDFATSALGG 742 S PGL+ G +G +G + PG GLP PP P G Sbjct: 1387 SGLPGLKGDTGPKGEKGHIGLIGLIGPPGEAGEKGDQGLPGVQG---PPGPK-------G 1436 Query: 743 QPGFPFGAAGRQSTPHSGP-GVNSPPSAGGGGGSSGG----GGGGGAYPPQPDFQPSQ 795 PG P G G S H GP GV P G GS G G G A PP P P++ Sbjct: 1437 DPGPP-GPIG--SLGHPGPPGVAGPLGQKGSKGSPGSMGPRGDTGPAGPPGPPGAPAE 1491 Score = 41.2 bits (95), Expect = 0.007 Identities = 110/420 (26%), Positives = 132/420 (31%), Gaps = 63/420 (15%) Query: 35 KAPAFHTGGPPGPVDPAMSALGEPPILGMNMEPYGFHARGH-SELHAGGLQAQPVHGFFG 93 + PA H G PPG D A G P + G + RG + GLQ P Sbjct: 1105 RGPAGHPG-PPG-ADGAQGRRGPPGLFGQKGDD---GVRGFVGVIGPPGLQGLPGPP--- 1156 Query: 94 GQQPHHGHPGSHHPHQHHPHFGGNFGGPDPGASCLHGGRLLGYGGAAGGLGSQ------- 146 G++ G GS PH G G L GG +G GA G G + Sbjct: 1157 GEKGEVGDVGSMGPHGAPGPRGPQGPTGSEGTPGLPGG--VGQPGAVGEKGERGDAGDPG 1214 Query: 147 PPFAEGYE-------HMAESQGPESFGPQRPGNLPDFHSSGASSHAVPAPCLPLDQSPNR 199 PP A G +S + GP PG GA P LP D P Sbjct: 1215 PPGAPGIPGPKGDIGEKGDSGPSGAAGP--PGKKGPPGEDGAKGSVGPTG-LPGDLGPPG 1271 Query: 200 AASFHGLPSSSGSDSHSLEPRRVTNQGAVD-SLEYNYPG----EAPSGHFDMFSPSDSEG 254 G+ S G +P V G S E PG PSGH +G Sbjct: 1272 DPGVSGIDGSPGEKG---DPGDVGGPGPPGASGEPGAPGPPGKRGPSGHMGREGREGEKG 1328 Query: 255 QL----PHYAAGRQVPGGAFP-----GASAMPRAAGMVGLSKMHAQPPQQQPQQQQQPQQ 305 P GR P GA G + G VG + P Q P P Sbjct: 1329 AKGEPGPDGPPGRTGPMGARGPPGRVGPEGLRGIPGPVGEPGLLGAPGQMGPPGPLGPSG 1388 Query: 306 QQQQHGVFFERFSGARKMPVGLEPSVGSRHPLMQPPQQAPP------PPQQQPPQQPPQQ 359 G + K +GL +G PP +A P Q PP Sbjct: 1389 LPGLKG---DTGPKGEKGHIGLIGLIG-------PPGEAGEKGDQGLPGVQGPPGPKGDP 1438 Query: 360 QPPPPPGLLVRQNSCPPALPRPQQGEAGTPS--GGLQDGGPMLPSQHAQFEYPIHRLENR 417 PP P G L A P Q+G G+P G D GP P +H L R Sbjct: 1439 GPPGPIGSLGHPGPPGVAGPLGQKGSKGSPGSMGPRGDTGPAGPPGPPGAPAELHGLRRR 1498 Score = 36.6 bits (83), Expect = 0.16 Identities = 75/313 (23%), Positives = 109/313 (34%), Gaps = 57/313 (18%) Query: 914 DGTSLSPNYTLESTSGNDGKPVSGGGGRGRGRRKRDSGHVSPGTFFDKYSAAPDSGGAPG 973 D +L+P T+ + G P G+G+GR+K G G K S P Sbjct: 223 DCDNLAPAATV-APQGEPETPRPRRKGKGKGRKK---GRGRKGKGRKKNKEIWTSSPPPD 278 Query: 974 VSPGQQQASGAAVGGSSAGETRGAPTPHEKALTSP-SWGKGAELLLGD-QPDL---IGSL 1028 + Q + + PTP +TS + G A +L PD +G+L Sbjct: 279 SAENQTSTD---IPKTETPAPNLPPTPTPLVVTSTVTTGLNATILERSLDPDSGTELGTL 335 Query: 1029 DGGAKSDSSSPNVGEFASDEVSTSYANEDEVS--------SSSDNPQALVKASRSPLVTG 1080 + A + + D + Y + + + P + K + G Sbjct: 336 ETKAAREDEEGDDSTMGPDFRAAEYPSRTQFQIFPGAGEKGAKGEPAVIEKGQQFEGPPG 395 Query: 1081 SPKLPPRGVGAGEHGPKAPPPALGLGIMSNSTSTPDSYGGGGGPGHPGTPGLEQVRTPTS 1140 +P P+GV G GP PP P G G G PG PG++ +R P Sbjct: 396 APG--PQGV-VGPSGPPGPP------------GFPGDPGPPGPAGLPGIPGIDGIRGPPG 440 Query: 1141 SSGAPP------PDEIHPLEILQAQIQLQRQQFSIS------------EDQPLGLKG--G 1180 + P + P+ QAQ Q QQ +S P+GL G G Sbjct: 441 TVIMMPFQFAGGSFKGPPVSFQQAQAQAVLQQTQLSMKGPPGPVGLTGRPGPVGLPGHPG 500 Query: 1181 KKGECAVGASGAQ 1193 KGE GA G Q Sbjct: 501 LKGE--EGAEGPQ 511 >gi|194294532 alpha 1 type XIII collagen isoform 20 [Homo sapiens] Length = 717 Score = 91.3 bits (225), Expect = 6e-18 Identities = 137/503 (27%), Positives = 182/503 (36%), Gaps = 99/503 (19%) Query: 681 QEPMRMPGEGHVPALPSPGLQFG-----GSLGGLGQLQSPG-AGVGLPSAASERRPPPPD 734 + P PG P P P + G G++G G++ SPG AG+ + R PP Sbjct: 109 EAPKTSPGCNCPPGPPGPTGRPGLPGDKGAIGMPGRVGSPGDAGLSIIGP----RGPPGQ 164 Query: 735 FATSALGGQPGFPFGAAGRQSTPHSGP----GVNSPPSAGGGGGSSGGGGGGGAYPPQPD 790 T G PG P G G+ H GP G+ PP G G G G G YP + Sbjct: 165 PGTRGFPGFPG-PIGLDGKPG--HPGPKGDMGLTGPPGQPGPQGQKGEKGQCGEYPHR-- 219 Query: 791 FQPSQRTSASKLGALSLGSFNKPSSKDNLFGQSCLAALSTACQN--MIASLGAPNLNVTF 848 CL+++ A ++ +IA P LN + Sbjct: 220 --------------------------------ECLSSMPAALRSSQIIALKLLPLLN-SV 246 Query: 849 NKKNPPEGKRKLSQNETDGAAVAGNPGSDYFPGGTAP----GAPGPGGPSGTSSSGSKAS 904 PP KR+ Q E A++ G PG PG + P G PGP GP G Sbjct: 247 RLAPPPVIKRRTFQGEQSQASIQGPPGPPGPPGPSGPLGHPGLPGPMGPPGLP------- 299 Query: 905 GPPNPPAQGDGTSLSPNYTLESTSGNDGKP----VSGGGGRGRGRRKRDSGHVSPGTFFD 960 GPP P +GD + + + G G P G G K + G PGT + Sbjct: 300 GPPGP--KGD-PGIQGYHGRKGERGMPGMPGKHGAKGAPGIAVAGMKGEPG--IPGTKGE 354 Query: 961 KYSAAPDSGGAPGVSPGQQQASGAAVGGSSAGETRGAPTPHEKALTSPSWGKGAELLLGD 1020 K A S G PG+ GQ+ G A G+S G RG P P L P KG + G Sbjct: 355 K--GAEGSPGLPGLL-GQKGEKGDA--GNSIGGGRGEPGP--PGLPGPPGPKGEAGVDGQ 407 Query: 1021 -----QPDLIGSLDG-------GAKSDSSSPNVGEFASDEVSTSYANEDEVSSSSDNPQA 1068 QP G G K P GE + + A ++ + + P Sbjct: 408 VGPPGQPGDKGERGAAGEQGPDGPKGSKGEPGKGEMVDYNGNINEALQEIRTLALMGPPG 467 Query: 1069 LVKASRSPLVTGSPK------LPPRGVGAGEHGPKAPPPALGLGIMSNSTSTPDSYGGGG 1122 L P G P LP GE GP+ P +G G G Sbjct: 468 LPGQIGPPGAPGIPGQKGEIGLPGPPGHDGEKGPRGKPGDMGPPGPQGPPGKDGPPGVKG 527 Query: 1123 GPGHPGTPGLEQVRTPTSSSGAP 1145 GHPG+PG + + T +G+P Sbjct: 528 ENGHPGSPGEKGEKGETGQAGSP 550 Score = 61.6 bits (148), Expect = 5e-09 Identities = 146/574 (25%), Positives = 185/574 (32%), Gaps = 75/574 (13%) Query: 593 GPVGGLAQPNFEREGGSTGA-GRLGTFEQQAPHLAQESAWFSGPHPPPGDLLPRRMGGSG 651 GP G +P + G+ G GR+G+ P A S GP PPG P G G Sbjct: 122 GPPGPTGRPGLPGDKGAIGMPGRVGS-----PGDAGLS--IIGPRGPPGQ--PGTRGFPG 172 Query: 652 LPADCGPHDPSLAPPPPPGGSGVLFRGPLQEPMRMPGEGHVPALPS-PGLQFGGSLGGLG 710 P G D P P G G+ GP +P +G P + S+ Sbjct: 173 FPGPIGL-DGKPGHPGPKGDMGLT--GPPGQPGPQGQKGEKGQCGEYPHRECLSSMPAAL 229 Query: 711 QLQSPGAGVGLPSAASERRPPPPDFATSALGGQPGFPFGAAGRQSTPHSGPGVNSPPSAG 770 + A LP S R PPP G+ Q++ PG PP Sbjct: 230 RSSQIIALKLLPLLNSVRLAPPPVIKRRTFQGEQS--------QASIQGPPGPPGPPGPS 281 Query: 771 GGGGSSGGGGGGGAY----PPQPDFQPSQRTSASKLGALSL-GSFNKPSSKDNLFGQSCL 825 G G G G G PP P P + + G + G K +K Sbjct: 282 GPLGHPGLPGPMGPPGLPGPPGPKGDPGIQGYHGRKGERGMPGMPGKHGAK--------- 332 Query: 826 AALSTACQNMIASLGAPNLNVTFNKKNPPEGKRKLSQNETDGAAVAGNPGSDYFPGGTAP 885 A A M G P + P L Q G A G PG P Sbjct: 333 GAPGIAVAGMKGEPGIPGTKGEKGAEGSPGLPGLLGQKGEKGDAGNSIGGGRGEPG--PP 390 Query: 886 GAPGPGGPSGTSSSGSKASGPPNPPAQGDGTSLSPNYTLESTSGNDGKPVSGGGGRGRGR 945 G PGP GP G + + GPP P + + G+ G+P G+G Sbjct: 391 GLPGPPGPKGEAGVDGQV-GPPGQPGDKGERGAAGEQGPDGPKGSKGEP-------GKGE 442 Query: 946 RKRDSGHVSPGTFFDKYSAAPDSGGAPGVSPGQQQASGAAVGGSSAGETRGAPTPHEKAL 1005 +G+++ + A G PG+ PGQ GA GE G P P Sbjct: 443 MVDYNGNINEALQEIRTLALM---GPPGL-PGQIGPPGAPGIPGQKGEI-GLPGP----- 492 Query: 1006 TSPSWGKGAELLLGDQ----PDLIGSLDG--GAKSDSSSPNVGEFASDEVSTSYAN---E 1056 KG GD P DG G K ++ P ++ T A E Sbjct: 493 PGHDGEKGPRGKPGDMGPPGPQGPPGKDGPPGVKGENGHPGSPGEKGEKGETGQAGSPGE 552 Query: 1057 DEVSSSSDNPQALVKASRSPLVTGSPKLP-------PRGVGAGEHGPKAPPPALGLGIMS 1109 + NP A V P G P P P+G AG G K G Sbjct: 553 KGEAGEKGNPGAEVPGLPGP--EGPPGPPGLQGVPGPKGE-AGLDGAKGEKGFQGEKGDR 609 Query: 1110 NSTSTPDSYGGGGGPGHPGTPGLEQVRTPTSSSG 1143 P + G G PG PGTPG V P G Sbjct: 610 GPLGLPGASGLDGRPGPPGTPGPIGVPGPAGPKG 643 Score = 57.4 bits (137), Expect = 9e-08 Identities = 129/530 (24%), Positives = 167/530 (31%), Gaps = 88/530 (16%) Query: 492 PGLPGEFTPPVPDSFPSGPPLQHPAPDHQSLQQQQQQQQQQQQQQQQQQQQQQQQQQQQR 551 PG PG P D +GPP Q P P Q Q+ ++ Q + ++ R Sbjct: 183 PGHPG----PKGDMGLTGPPGQ-PGP-------QGQKGEKGQCGEYPHRECLSSMPAALR 230 Query: 552 QNAALMIKQMASRNQQQRLRQPNLAQLGHPGDVGQGGLVHGGPVGGLAQPNFEREGGSTG 611 + + +K + N + P + + G+ Q + GP G P G S Sbjct: 231 SSQIIALKLLPLLNSVRLAPPPVIKRRTFQGEQSQASIQ--GPPGPPGPP-----GPSGP 283 Query: 612 AGRLGTFEQQAPHLAQESAWFSGPHPPPGDL----LPRRMGGSGLPADCGPHDPSLAPPP 667 G G P GP P GD R G G+P G H AP Sbjct: 284 LGHPGLPGPMGP------PGLPGPPGPKGDPGIQGYHGRKGERGMPGMPGKHGAKGAP-- 335 Query: 668 PPGGSGVLFRGPLQEPMRMPGEGHVPALPSPGLQFGGSLGGLGQLQSPGAGVGLPSAASE 727 G+ G EP +G A SPGL G LG G+ G +G Sbjct: 336 -----GIAVAGMKGEPGIPGTKGEKGAEGSPGLP--GLLGQKGEKGDAGNSIG----GGR 384 Query: 728 RRPPPPDFATSALGGQPGFPFGAAG--RQSTPHSGPGVNSPPSAGGGGGSSGGGGGGG-- 783 P PP L G PG P G AG Q P PG A G G G G G Sbjct: 385 GEPGPP-----GLPGPPG-PKGEAGVDGQVGPPGQPGDKGERGAAGEQGPDGPKGSKGEP 438 Query: 784 AYPPQPDFQPSQRTSASKLGALSL-------GSFNKPSSKDNLFGQSCLAAL-------- 828 D+ + + ++ L+L G P + + GQ L Sbjct: 439 GKGEMVDYNGNINEALQEIRTLALMGPPGLPGQIGPPGAP-GIPGQKGEIGLPGPPGHDG 497 Query: 829 STACQNMIASLGAPNLNVTFNKKNPPEGK----------RKLSQNETDGAAVAGNPGS-- 876 + +G P K PP K K + ET A G G Sbjct: 498 EKGPRGKPGDMGPPGPQGPPGKDGPPGVKGENGHPGSPGEKGEKGETGQAGSPGEKGEAG 557 Query: 877 -DYFPGGTAPGAPGPGGPSGTSSSGSKASGPPNPPAQGDGTSLSPNYTLESTSGNDGKPV 935 PG PG PGP GP G G P P + + G+ G P+ Sbjct: 558 EKGNPGAEVPGLPGPEGPPGPPG----LQGVPGPKGEAGLDGAKGEKGFQGEKGDRG-PL 612 Query: 936 SGGGGRGRGRRKRDSGHVSPGTFFDKYSAAPDSGGAPGVSPGQQQASGAA 985 G G R G +PG A P PG +GAA Sbjct: 613 GLPGASGLDGRPGPPG--TPGPIGVPGPAGPKGERGSKGDPGMTGPTGAA 660 Score = 55.5 bits (132), Expect = 3e-07 Identities = 100/383 (26%), Positives = 125/383 (32%), Gaps = 40/383 (10%) Query: 579 GHPGDVGQGGLVHGGPVGGLAQPNFER--EGGSTGAGR--LGTFEQQAPHLAQESAWFSG 634 G PG G+ G + GL E+ G S G GR G P + A G Sbjct: 347 GIPGTKGEKGAEGSPGLPGLLGQKGEKGDAGNSIGGGRGEPGPPGLPGPPGPKGEAGVDG 406 Query: 635 PHPPPGDLLPRRMGGSGLPADCGPHDPSLAPPPPPGGSGVLFRGPLQEPMRMPGEGHVPA 694 PPG P G G + GP P + P G V + G + E ++ E A Sbjct: 407 QVGPPGQ--PGDKGERGAAGEQGPDGPKGSKGEPGKGEMVDYNGNINEALQ---EIRTLA 461 Query: 695 LPSPGLQFGGSLGGLGQLQSPGAGVGLPSAASERRPPPPDFATSALG--GQPGFPFGAAG 752 L P G GQ+ PGA G+P E P P G G+PG G G Sbjct: 462 LMGPP-------GLPGQIGPPGAP-GIPGQKGEIGLPGPPGHDGEKGPRGKPG-DMGPPG 512 Query: 753 RQSTP-HSGP----GVNSPPSAGGGGGSSGGGGGGGAYPPQPDFQPSQRTSASKLGALSL 807 Q P GP G N P + G G G G G+ + + A G Sbjct: 513 PQGPPGKDGPPGVKGENGHPGSPGEKGEKGETGQAGSPGEKGEAGEKGNPGAEVPGLPGP 572 Query: 808 GSFNKPSSKDNLFGQSCLAALSTAC--------QNMIASLGAPNLNVTFNKKNPPEGKRK 859 P + G A L A + LG P + + PP Sbjct: 573 EGPPGPPGLQGVPGPKGEAGLDGAKGEKGFQGEKGDRGPLGLPGASGLDGRPGPPGTPGP 632 Query: 860 LSQNETDGAAVAGNPGSDYFPGGTAP----GAPGPGGPSGTSSS-GSKASGPPNPPAQGD 914 + G G GS PG T P G PG GP G + G + P Sbjct: 633 IGVPGPAGPK--GERGSKGDPGMTGPTGAAGLPGLHGPPGDKGNRGERGKKGSRGPKGDK 690 Query: 915 GTSLSPNYTLESTSGNDGKPVSG 937 G +P G DG PV G Sbjct: 691 GDQGAPGLDAPCPLGEDGLPVQG 713 Score = 35.8 bits (81), Expect = 0.28 Identities = 92/355 (25%), Positives = 121/355 (34%), Gaps = 45/355 (12%) Query: 43 GPPGPVDPAMSALGEPPILGMNMEPYGFHARGHSELHAGGLQAQP-VHGFFG--GQQPHH 99 GPPGP P+ LG P + G M P G G + P + G+ G G++ Sbjct: 273 GPPGPPGPS-GPLGHPGLPGP-MGPPGLPG-------PPGPKGDPGIQGYHGRKGERGMP 323 Query: 100 GHPGSHHPHQHHPHFG--GNFGGPD-PGASCLHGGRLLGYGGAAGGLGSQPPFAEGYEHM 156 G PG H + P G G P PG G G G G LG + + + Sbjct: 324 GMPGKHGA-KGAPGIAVAGMKGEPGIPGTKGEKGAE--GSPGLPGLLGQKGEKGDAGNSI 380 Query: 157 AESQGPESFGPQRPGNLPDFHSSGASSHAVPAPCLPLDQSPNRAASFHGLPSSSGSDSHS 216 +G E P PG +G P P P D+ AA G GS Sbjct: 381 GGGRG-EPGPPGLPGPPGPKGEAGVDGQVGP-PGQPGDKGERGAAGEQGPDGPKGSKGEP 438 Query: 217 LEPRRVTNQGAVDSLEYNYPGEAPSGHFDMFSPSDSEGQL-PHYAAGRQVPGGAFPGASA 275 + V G ++ A G P GQ+ P A G +PG G Sbjct: 439 GKGEMVDYNGNINEALQEIRTLALMG------PPGLPGQIGPPGAPG--IPGQK--GEIG 488 Query: 276 MPRAAGMVGLSKMHAQPPQQQPQQQQQPQQQQQQHGVFFERF---SGARKMPVGLEPSVG 332 +P G G +P P Q P + GV E S K G G Sbjct: 489 LPGPPGHDGEKGPRGKPGDMGPPGPQGPPGKDGPPGVKGENGHPGSPGEKGEKGETGQAG 548 Query: 333 SRHPLMQPPQQAPPPPQQQPPQQPPQQQPPPPPGLLVRQNSCPPALPRPQQGEAG 387 S + ++ P + P P + PP PPGL +P P +GEAG Sbjct: 549 SPGEKGEAGEKGNPGAEV--PGLPGPEGPPGPPGL--------QGVPGP-KGEAG 592 >gi|22027583 alpha 1 type XIII collagen isoform 7 [Homo sapiens] Length = 703 Score = 90.9 bits (224), Expect = 7e-18 Identities = 137/503 (27%), Positives = 182/503 (36%), Gaps = 99/503 (19%) Query: 681 QEPMRMPGEGHVPALPSPGLQFG-----GSLGGLGQLQSPG-AGVGLPSAASERRPPPPD 734 + P PG PA P + G G++G G++ SPG AG+ + R PP Sbjct: 109 EAPKTSPGCNCPPAFQGPTGRPGLPGDKGAIGMPGRVGSPGDAGLSIIGP----RGPPGQ 164 Query: 735 FATSALGGQPGFPFGAAGRQSTPHSGP----GVNSPPSAGGGGGSSGGGGGGGAYPPQPD 790 T G PG P G G+ H GP G+ PP G G G G G YP + Sbjct: 165 PGTRGFPGFPG-PIGLDGKPG--HPGPKGDMGLTGPPGQPGPQGQKGEKGQCGEYPHR-- 219 Query: 791 FQPSQRTSASKLGALSLGSFNKPSSKDNLFGQSCLAALSTACQN--MIASLGAPNLNVTF 848 CL+++ A ++ +IA P LN + Sbjct: 220 --------------------------------ECLSSMPAALRSSQIIALKLLPLLN-SV 246 Query: 849 NKKNPPEGKRKLSQNETDGAAVAGNPGSDYFPGGTAP----GAPGPGGPSGTSSSGSKAS 904 PP KR+ Q E A++ G PG PG + P G PGP GP G Sbjct: 247 RLAPPPVIKRRTFQGEQSQASIQGPPGPPGPPGPSGPLGHPGLPGPMGPPGLP------- 299 Query: 905 GPPNPPAQGDGTSLSPNYTLESTSGNDGKP----VSGGGGRGRGRRKRDSGHVSPGTFFD 960 GPP P +GD + + + G G P G G K + G PGT + Sbjct: 300 GPPGP--KGD-PGIQGYHGRKGERGMPGMPGKHGAKGAPGIAVAGMKGEPG--IPGTKGE 354 Query: 961 KYSAAPDSGGAPGVSPGQQQASGAAVGGSSAGETRGAPTPHEKALTSPSWGKGAELLLGD 1020 K A S G PG+ GQ+ G A G+S G RG P P L P KG + G Sbjct: 355 K--GAEGSPGLPGLL-GQKGEKGDA--GNSIGGGRGEPGP--PGLPGPPGPKGEAGVDGQ 407 Query: 1021 -----QPDLIGSLDG-------GAKSDSSSPNVGEFASDEVSTSYANEDEVSSSSDNPQA 1068 QP G G K P GE + + A ++ + + P Sbjct: 408 VGPPGQPGDKGERGAAGEQGPDGPKGSKGEPGKGEMVDYNGNINEALQEIRTLALMGPPG 467 Query: 1069 LVKASRSPLVTGSPK------LPPRGVGAGEHGPKAPPPALGLGIMSNSTSTPDSYGGGG 1122 L P G P LP GE GP+ P +G G G Sbjct: 468 LPGQIGPPGAPGIPGQKGEIGLPGPPGHDGEKGPRGKPGDMGPPGPQGPPGKDGPPGVKG 527 Query: 1123 GPGHPGTPGLEQVRTPTSSSGAP 1145 GHPG+PG + + T +G+P Sbjct: 528 ENGHPGSPGEKGEKGETGQAGSP 550 Score = 59.7 bits (143), Expect = 2e-08 Identities = 143/553 (25%), Positives = 176/553 (31%), Gaps = 87/553 (15%) Query: 632 FSGPHPPPGDLLPRRMGGSGLPADCG-PHDPSLA---PPPPPGGSGVL----FRGP--LQ 681 F GP PG LP G G+P G P D L+ P PPG G F GP L Sbjct: 123 FQGPTGRPG--LPGDKGAIGMPGRVGSPGDAGLSIIGPRGPPGQPGTRGFPGFPGPIGLD 180 Query: 682 EPMRMPGEGHVPALPSPGLQFG--GSLGGLGQ---------LQSPGAGVG---------L 721 PG L P Q G G G GQ L S A + L Sbjct: 181 GKPGHPGPKGDMGLTGPPGQPGPQGQKGEKGQCGEYPHRECLSSMPAALRSSQIIALKLL 240 Query: 722 PSAASERRPPPPDFATSALGGQPGFPFGAAGRQSTPHSGPGVNSPPSAGGGGGSSGGGGG 781 P S R PPP G+ Q++ PG PP G G G G Sbjct: 241 PLLNSVRLAPPPVIKRRTFQGEQS--------QASIQGPPGPPGPPGPSGPLGHPGLPGP 292 Query: 782 GGAY----PPQPDFQPSQRTSASKLGALSL-GSFNKPSSKDNLFGQSCLAALSTACQNMI 836 G PP P P + + G + G K +K A A M Sbjct: 293 MGPPGLPGPPGPKGDPGIQGYHGRKGERGMPGMPGKHGAK---------GAPGIAVAGMK 343 Query: 837 ASLGAPNLNVTFNKKNPPEGKRKLSQNETDGAAVAGNPGSDYFPGGTAPGAPGPGGPSGT 896 G P + P L Q G A G PG PG PGP GP G Sbjct: 344 GEPGIPGTKGEKGAEGSPGLPGLLGQKGEKGDAGNSIGGGRGEPG--PPGLPGPPGPKGE 401 Query: 897 SSSGSKASGPPNPPAQGDGTSLSPNYTLESTSGNDGKPVSGGGGRGRGRRKRDSGHVSPG 956 + + GPP P + + G+ G+P G+G +G+++ Sbjct: 402 AGVDGQV-GPPGQPGDKGERGAAGEQGPDGPKGSKGEP-------GKGEMVDYNGNINEA 453 Query: 957 TFFDKYSAAPDSGGAPGVSPGQQQASGAAVGGSSAGETRGAPTPHEKALTSPSWGKGAEL 1016 + A G PG+ PGQ GA GE G P P KG Sbjct: 454 LQEIRTLALM---GPPGL-PGQIGPPGAPGIPGQKGEI-GLPGP-----PGHDGEKGPRG 503 Query: 1017 LLGDQ----PDLIGSLDG--GAKSDSSSPNVGEFASDEVSTSYANEDEVSSSSDNPQALV 1070 GD P DG G K ++ P ++ T A S + +A Sbjct: 504 KPGDMGPPGPQGPPGKDGPPGVKGENGHPGSPGEKGEKGETGQA-----GSPGEKGEAGE 558 Query: 1071 KASRSPLVTGSPKLPPRGVGAGEHGPKAPPPALGLGIMSNSTSTPDSYGGGGGPGHPGTP 1130 K +P G +P AG G K G P + G G PG PGTP Sbjct: 559 KG--NPGAEGLQGVPGPKGEAGLDGAKGEKGFQGEKGDRGPLGLPGASGLDGRPGPPGTP 616 Query: 1131 GLEQVRTPTSSSG 1143 G V P G Sbjct: 617 GPIGVPGPAGPKG 629 Score = 59.7 bits (143), Expect = 2e-08 Identities = 99/374 (26%), Positives = 124/374 (33%), Gaps = 36/374 (9%) Query: 579 GHPGDVGQGGLVHGGPVGGLAQPNFER--EGGSTGAGR--LGTFEQQAPHLAQESAWFSG 634 G PG G+ G + GL E+ G S G GR G P + A G Sbjct: 347 GIPGTKGEKGAEGSPGLPGLLGQKGEKGDAGNSIGGGRGEPGPPGLPGPPGPKGEAGVDG 406 Query: 635 PHPPPGDLLPRRMGGSGLPADCGPHDPSLAPPPPPGGSGVLFRGPLQEPMRMPGEGHVPA 694 PPG P G G + GP P + P G V + G + E ++ E A Sbjct: 407 QVGPPGQ--PGDKGERGAAGEQGPDGPKGSKGEPGKGEMVDYNGNINEALQ---EIRTLA 461 Query: 695 LPSPGLQFGGSLGGLGQLQSPGAGVGLPSAASERRPPPPDFATSALG--GQPGFPFGAAG 752 L P G GQ+ PGA G+P E P P G G+PG G G Sbjct: 462 LMGPP-------GLPGQIGPPGAP-GIPGQKGEIGLPGPPGHDGEKGPRGKPG-DMGPPG 512 Query: 753 RQSTPHSGPGVNSPPSAGGGGGSSGGGGGGGAYPPQPDF-QPSQRTSASKLG---ALSLG 808 P PG + PP G G G G G P ++ A + G A L Sbjct: 513 ----PQGPPGKDGPPGVKGENGHPGSPGEKGEKGETGQAGSPGEKGEAGEKGNPGAEGLQ 568 Query: 809 SFNKPSSKDNLFGQSCLAALSTACQNMIASLGAPNLNVTFNKKNPPEGKRKLSQNETDGA 868 P + L G + LG P + + PP + G Sbjct: 569 GVPGPKGEAGLDGAKGEKGFQGEKGDR-GPLGLPGASGLDGRPGPPGTPGPIGVPGPAGP 627 Query: 869 AVAGNPGSDYFPGGTAP----GAPGPGGPSGTSSS-GSKASGPPNPPAQGDGTSLSPNYT 923 G GS PG T P G PG GP G + G + P G +P Sbjct: 628 K--GERGSKGDPGMTGPTGAAGLPGLHGPPGDKGNRGERGKKGSRGPKGDKGDQGAPGLD 685 Query: 924 LESTSGNDGKPVSG 937 G DG PV G Sbjct: 686 APCPLGEDGLPVQG 699 Score = 35.4 bits (80), Expect = 0.36 Identities = 89/388 (22%), Positives = 122/388 (31%), Gaps = 61/388 (15%) Query: 43 GPPGPV-DPAMSAL-GEPPILGMNMEPYGFHARGHSELHAGGLQAQPVHGFFGGQQPHHG 100 GPPGP DP + G GM P A+G + G++ +P G++ G Sbjct: 300 GPPGPKGDPGIQGYHGRKGERGMPGMPGKHGAKGAPGIAVAGMKGEPGIPGTKGEKGAEG 359 Query: 101 HPGSHHPHQHHPHFGGNFGGPDPGASCLHGGRLLGYGGAAGGLGSQPPFAEGYEHMAESQ 160 PG P G G + + GGR G G G G PP +G + Sbjct: 360 SPGL-------PGLLGQKGEKGDAGNSIGGGR--GEPGPPGLPG--PPGPKGEAGVDGQV 408 Query: 161 GPESFGPQRPGNLPDFHSSGAS-------SHAVPAPCLPLDQSPN--------RAASFHG 205 GP P +PG+ + ++G S P +D + N R + G Sbjct: 409 GP----PGQPGDKGERGAAGEQGPDGPKGSKGEPGKGEMVDYNGNINEALQEIRTLALMG 464 Query: 206 LPSSSGSDSHSLEPRRVTNQGAVDSLEYNYPGEAPSGHFDMFSPSDSEGQL----PHYAA 261 P G P +G E PG P GH P G + P Sbjct: 465 PPGLPGQIGPPGAPGIPGQKG-----EIGLPG--PPGHDGEKGPRGKPGDMGPPGPQGPP 517 Query: 262 GRQVPGGA-----FPGASAMPRAAGMVGLSKMHAQPPQQQPQQQQQPQQQQQQHGVFFER 316 G+ P G PG+ G G + + + + + Q G E Sbjct: 518 GKDGPPGVKGENGHPGSPGEKGEKGETGQAGSPGEKGEAGEKGNPGAEGLQGVPGPKGEA 577 Query: 317 FSGARKMPVGLEPSVGSRHPLMQPPQQAPPPPQQQPPQQPPQQQPPPPPGLLVRQNSCPP 376 K G + G R PL P P P P PG P Sbjct: 578 GLDGAKGEKGFQGEKGDRGPLGLPGASG----LDGRPGPPGTPGPIGVPG---------P 624 Query: 377 ALPRPQQGEAGTPSGGLQDGGPMLPSQH 404 A P+ ++G G P G LP H Sbjct: 625 AGPKGERGSKGDPGMTGPTGAAGLPGLH 652 >gi|22027565 alpha 1 type XIII collagen isoform 1 [Homo sapiens] Length = 717 Score = 90.9 bits (224), Expect = 7e-18 Identities = 137/503 (27%), Positives = 182/503 (36%), Gaps = 99/503 (19%) Query: 681 QEPMRMPGEGHVPALPSPGLQFG-----GSLGGLGQLQSPG-AGVGLPSAASERRPPPPD 734 + P PG PA P + G G++G G++ SPG AG+ + R PP Sbjct: 109 EAPKTSPGCNCPPAFQGPTGRPGLPGDKGAIGMPGRVGSPGDAGLSIIGP----RGPPGQ 164 Query: 735 FATSALGGQPGFPFGAAGRQSTPHSGP----GVNSPPSAGGGGGSSGGGGGGGAYPPQPD 790 T G PG P G G+ H GP G+ PP G G G G G YP + Sbjct: 165 PGTRGFPGFPG-PIGLDGKPG--HPGPKGDMGLTGPPGQPGPQGQKGEKGQCGEYPHR-- 219 Query: 791 FQPSQRTSASKLGALSLGSFNKPSSKDNLFGQSCLAALSTACQN--MIASLGAPNLNVTF 848 CL+++ A ++ +IA P LN + Sbjct: 220 --------------------------------ECLSSMPAALRSSQIIALKLLPLLN-SV 246 Query: 849 NKKNPPEGKRKLSQNETDGAAVAGNPGSDYFPGGTAP----GAPGPGGPSGTSSSGSKAS 904 PP KR+ Q E A++ G PG PG + P G PGP GP G Sbjct: 247 RLAPPPVIKRRTFQGEQSQASIQGPPGPPGPPGPSGPLGHPGLPGPMGPPGLP------- 299 Query: 905 GPPNPPAQGDGTSLSPNYTLESTSGNDGKP----VSGGGGRGRGRRKRDSGHVSPGTFFD 960 GPP P +GD + + + G G P G G K + G PGT + Sbjct: 300 GPPGP--KGD-PGIQGYHGRKGERGMPGMPGKHGAKGAPGIAVAGMKGEPG--IPGTKGE 354 Query: 961 KYSAAPDSGGAPGVSPGQQQASGAAVGGSSAGETRGAPTPHEKALTSPSWGKGAELLLGD 1020 K A S G PG+ GQ+ G A G+S G RG P P L P KG + G Sbjct: 355 K--GAEGSPGLPGLL-GQKGEKGDA--GNSIGGGRGEPGP--PGLPGPPGPKGEAGVDGQ 407 Query: 1021 -----QPDLIGSLDG-------GAKSDSSSPNVGEFASDEVSTSYANEDEVSSSSDNPQA 1068 QP G G K P GE + + A ++ + + P Sbjct: 408 VGPPGQPGDKGERGAAGEQGPDGPKGSKGEPGKGEMVDYNGNINEALQEIRTLALMGPPG 467 Query: 1069 LVKASRSPLVTGSPK------LPPRGVGAGEHGPKAPPPALGLGIMSNSTSTPDSYGGGG 1122 L P G P LP GE GP+ P +G G G Sbjct: 468 LPGQIGPPGAPGIPGQKGEIGLPGPPGHDGEKGPRGKPGDMGPPGPQGPPGKDGPPGVKG 527 Query: 1123 GPGHPGTPGLEQVRTPTSSSGAP 1145 GHPG+PG + + T +G+P Sbjct: 528 ENGHPGSPGEKGEKGETGQAGSP 550 Score = 62.4 bits (150), Expect = 3e-09 Identities = 148/563 (26%), Positives = 179/563 (31%), Gaps = 93/563 (16%) Query: 632 FSGPHPPPGDLLPRRMGGSGLPADCG-PHDPSLA---PPPPPGGSGVL----FRGP--LQ 681 F GP PG LP G G+P G P D L+ P PPG G F GP L Sbjct: 123 FQGPTGRPG--LPGDKGAIGMPGRVGSPGDAGLSIIGPRGPPGQPGTRGFPGFPGPIGLD 180 Query: 682 EPMRMPGEGHVPALPSPGLQFG--GSLGGLGQ---------LQSPGAGVG---------L 721 PG L P Q G G G GQ L S A + L Sbjct: 181 GKPGHPGPKGDMGLTGPPGQPGPQGQKGEKGQCGEYPHRECLSSMPAALRSSQIIALKLL 240 Query: 722 PSAASERRPPPPDFATSALGGQPGFPFGAAGRQSTPHSGPGVNSPPSAGGGGGSSGGGGG 781 P S R PPP G+ Q++ PG PP G G G G Sbjct: 241 PLLNSVRLAPPPVIKRRTFQGEQS--------QASIQGPPGPPGPPGPSGPLGHPGLPGP 292 Query: 782 GGAY----PPQPDFQPSQRTSASKLGALSL-GSFNKPSSKDNLFGQSCLAALSTACQNMI 836 G PP P P + + G + G K +K A A M Sbjct: 293 MGPPGLPGPPGPKGDPGIQGYHGRKGERGMPGMPGKHGAK---------GAPGIAVAGMK 343 Query: 837 ASLGAPNLNVTFNKKNPPEGKRKLSQNETDGAAVAGNPGSDYFPGGTAPGAPGPGGPSGT 896 G P + P L Q G A G PG PG PGP GP G Sbjct: 344 GEPGIPGTKGEKGAEGSPGLPGLLGQKGEKGDAGNSIGGGRGEPG--PPGLPGPPGPKGE 401 Query: 897 SSSGSKASGPPNPPAQGDGTSLSPNYTLESTSGNDGKPVSGGGGRGRGRRKRDSGHVSPG 956 + + GPP P + + G+ G+P G+G +G+++ Sbjct: 402 AGVDGQV-GPPGQPGDKGERGAAGEQGPDGPKGSKGEP-------GKGEMVDYNGNINEA 453 Query: 957 TFFDKYSAAPDSGGAPGVSPGQQQASGAAVGGSSAGETRGAPTPHEKALTSPSWGKGAEL 1016 + A G PG+ PGQ GA GE G P P KG Sbjct: 454 LQEIRTLALM---GPPGL-PGQIGPPGAPGIPGQKGEI-GLPGP-----PGHDGEKGPRG 503 Query: 1017 LLGDQ----PDLIGSLDG--GAKSDSSSPNVGEFASDEVSTSYAN---EDEVSSSSDNPQ 1067 GD P DG G K ++ P ++ T A E + NP Sbjct: 504 KPGDMGPPGPQGPPGKDGPPGVKGENGHPGSPGEKGEKGETGQAGSPGEKGEAGEKGNPG 563 Query: 1068 ALVKASRSPLVTGSPKLP-------PRGVGAGEHGPKAPPPALGLGIMSNSTSTPDSYGG 1120 A V P G P P P+G AG G K G P + G Sbjct: 564 AEVPGLPGP--EGPPGPPGLQGVPGPKGE-AGLDGAKGEKGFQGEKGDRGPLGLPGASGL 620 Query: 1121 GGGPGHPGTPGLEQVRTPTSSSG 1143 G PG PGTPG V P G Sbjct: 621 DGRPGPPGTPGPIGVPGPAGPKG 643 Score = 57.4 bits (137), Expect = 9e-08 Identities = 129/530 (24%), Positives = 167/530 (31%), Gaps = 88/530 (16%) Query: 492 PGLPGEFTPPVPDSFPSGPPLQHPAPDHQSLQQQQQQQQQQQQQQQQQQQQQQQQQQQQR 551 PG PG P D +GPP Q P P Q Q+ ++ Q + ++ R Sbjct: 183 PGHPG----PKGDMGLTGPPGQ-PGP-------QGQKGEKGQCGEYPHRECLSSMPAALR 230 Query: 552 QNAALMIKQMASRNQQQRLRQPNLAQLGHPGDVGQGGLVHGGPVGGLAQPNFEREGGSTG 611 + + +K + N + P + + G+ Q + GP G P G S Sbjct: 231 SSQIIALKLLPLLNSVRLAPPPVIKRRTFQGEQSQASIQ--GPPGPPGPP-----GPSGP 283 Query: 612 AGRLGTFEQQAPHLAQESAWFSGPHPPPGDL----LPRRMGGSGLPADCGPHDPSLAPPP 667 G G P GP P GD R G G+P G H AP Sbjct: 284 LGHPGLPGPMGP------PGLPGPPGPKGDPGIQGYHGRKGERGMPGMPGKHGAKGAP-- 335 Query: 668 PPGGSGVLFRGPLQEPMRMPGEGHVPALPSPGLQFGGSLGGLGQLQSPGAGVGLPSAASE 727 G+ G EP +G A SPGL G LG G+ G +G Sbjct: 336 -----GIAVAGMKGEPGIPGTKGEKGAEGSPGLP--GLLGQKGEKGDAGNSIG----GGR 384 Query: 728 RRPPPPDFATSALGGQPGFPFGAAG--RQSTPHSGPGVNSPPSAGGGGGSSGGGGGGG-- 783 P PP L G PG P G AG Q P PG A G G G G G Sbjct: 385 GEPGPP-----GLPGPPG-PKGEAGVDGQVGPPGQPGDKGERGAAGEQGPDGPKGSKGEP 438 Query: 784 AYPPQPDFQPSQRTSASKLGALSL-------GSFNKPSSKDNLFGQSCLAAL-------- 828 D+ + + ++ L+L G P + + GQ L Sbjct: 439 GKGEMVDYNGNINEALQEIRTLALMGPPGLPGQIGPPGAP-GIPGQKGEIGLPGPPGHDG 497 Query: 829 STACQNMIASLGAPNLNVTFNKKNPPEGK----------RKLSQNETDGAAVAGNPGS-- 876 + +G P K PP K K + ET A G G Sbjct: 498 EKGPRGKPGDMGPPGPQGPPGKDGPPGVKGENGHPGSPGEKGEKGETGQAGSPGEKGEAG 557 Query: 877 -DYFPGGTAPGAPGPGGPSGTSSSGSKASGPPNPPAQGDGTSLSPNYTLESTSGNDGKPV 935 PG PG PGP GP G G P P + + G+ G P+ Sbjct: 558 EKGNPGAEVPGLPGPEGPPGPPG----LQGVPGPKGEAGLDGAKGEKGFQGEKGDRG-PL 612 Query: 936 SGGGGRGRGRRKRDSGHVSPGTFFDKYSAAPDSGGAPGVSPGQQQASGAA 985 G G R G +PG A P PG +GAA Sbjct: 613 GLPGASGLDGRPGPPG--TPGPIGVPGPAGPKGERGSKGDPGMTGPTGAA 660 Score = 55.5 bits (132), Expect = 3e-07 Identities = 100/383 (26%), Positives = 125/383 (32%), Gaps = 40/383 (10%) Query: 579 GHPGDVGQGGLVHGGPVGGLAQPNFER--EGGSTGAGR--LGTFEQQAPHLAQESAWFSG 634 G PG G+ G + GL E+ G S G GR G P + A G Sbjct: 347 GIPGTKGEKGAEGSPGLPGLLGQKGEKGDAGNSIGGGRGEPGPPGLPGPPGPKGEAGVDG 406 Query: 635 PHPPPGDLLPRRMGGSGLPADCGPHDPSLAPPPPPGGSGVLFRGPLQEPMRMPGEGHVPA 694 PPG P G G + GP P + P G V + G + E ++ E A Sbjct: 407 QVGPPGQ--PGDKGERGAAGEQGPDGPKGSKGEPGKGEMVDYNGNINEALQ---EIRTLA 461 Query: 695 LPSPGLQFGGSLGGLGQLQSPGAGVGLPSAASERRPPPPDFATSALG--GQPGFPFGAAG 752 L P G GQ+ PGA G+P E P P G G+PG G G Sbjct: 462 LMGPP-------GLPGQIGPPGAP-GIPGQKGEIGLPGPPGHDGEKGPRGKPG-DMGPPG 512 Query: 753 RQSTP-HSGP----GVNSPPSAGGGGGSSGGGGGGGAYPPQPDFQPSQRTSASKLGALSL 807 Q P GP G N P + G G G G G+ + + A G Sbjct: 513 PQGPPGKDGPPGVKGENGHPGSPGEKGEKGETGQAGSPGEKGEAGEKGNPGAEVPGLPGP 572 Query: 808 GSFNKPSSKDNLFGQSCLAALSTAC--------QNMIASLGAPNLNVTFNKKNPPEGKRK 859 P + G A L A + LG P + + PP Sbjct: 573 EGPPGPPGLQGVPGPKGEAGLDGAKGEKGFQGEKGDRGPLGLPGASGLDGRPGPPGTPGP 632 Query: 860 LSQNETDGAAVAGNPGSDYFPGGTAP----GAPGPGGPSGTSSS-GSKASGPPNPPAQGD 914 + G G GS PG T P G PG GP G + G + P Sbjct: 633 IGVPGPAGPK--GERGSKGDPGMTGPTGAAGLPGLHGPPGDKGNRGERGKKGSRGPKGDK 690 Query: 915 GTSLSPNYTLESTSGNDGKPVSG 937 G +P G DG PV G Sbjct: 691 GDQGAPGLDAPCPLGEDGLPVQG 713 Score = 35.8 bits (81), Expect = 0.28 Identities = 92/355 (25%), Positives = 121/355 (34%), Gaps = 45/355 (12%) Query: 43 GPPGPVDPAMSALGEPPILGMNMEPYGFHARGHSELHAGGLQAQP-VHGFFG--GQQPHH 99 GPPGP P+ LG P + G M P G G + P + G+ G G++ Sbjct: 273 GPPGPPGPS-GPLGHPGLPGP-MGPPGLPG-------PPGPKGDPGIQGYHGRKGERGMP 323 Query: 100 GHPGSHHPHQHHPHFG--GNFGGPD-PGASCLHGGRLLGYGGAAGGLGSQPPFAEGYEHM 156 G PG H + P G G P PG G G G G LG + + + Sbjct: 324 GMPGKHGA-KGAPGIAVAGMKGEPGIPGTKGEKGAE--GSPGLPGLLGQKGEKGDAGNSI 380 Query: 157 AESQGPESFGPQRPGNLPDFHSSGASSHAVPAPCLPLDQSPNRAASFHGLPSSSGSDSHS 216 +G E P PG +G P P P D+ AA G GS Sbjct: 381 GGGRG-EPGPPGLPGPPGPKGEAGVDGQVGP-PGQPGDKGERGAAGEQGPDGPKGSKGEP 438 Query: 217 LEPRRVTNQGAVDSLEYNYPGEAPSGHFDMFSPSDSEGQL-PHYAAGRQVPGGAFPGASA 275 + V G ++ A G P GQ+ P A G +PG G Sbjct: 439 GKGEMVDYNGNINEALQEIRTLALMG------PPGLPGQIGPPGAPG--IPGQK--GEIG 488 Query: 276 MPRAAGMVGLSKMHAQPPQQQPQQQQQPQQQQQQHGVFFERF---SGARKMPVGLEPSVG 332 +P G G +P P Q P + GV E S K G G Sbjct: 489 LPGPPGHDGEKGPRGKPGDMGPPGPQGPPGKDGPPGVKGENGHPGSPGEKGEKGETGQAG 548 Query: 333 SRHPLMQPPQQAPPPPQQQPPQQPPQQQPPPPPGLLVRQNSCPPALPRPQQGEAG 387 S + ++ P + P P + PP PPGL +P P +GEAG Sbjct: 549 SPGEKGEAGEKGNPGAEV--PGLPGPEGPPGPPGL--------QGVPGP-KGEAG 592 >gi|22027587 alpha 1 type XIII collagen isoform 8 [Homo sapiens] Length = 705 Score = 90.9 bits (224), Expect = 7e-18 Identities = 137/503 (27%), Positives = 182/503 (36%), Gaps = 99/503 (19%) Query: 681 QEPMRMPGEGHVPALPSPGLQFG-----GSLGGLGQLQSPG-AGVGLPSAASERRPPPPD 734 + P PG PA P + G G++G G++ SPG AG+ + R PP Sbjct: 109 EAPKTSPGCNCPPAFQGPTGRPGLPGDKGAIGMPGRVGSPGDAGLSIIGP----RGPPGQ 164 Query: 735 FATSALGGQPGFPFGAAGRQSTPHSGP----GVNSPPSAGGGGGSSGGGGGGGAYPPQPD 790 T G PG P G G+ H GP G+ PP G G G G G YP + Sbjct: 165 PGTRGFPGFPG-PIGLDGKPG--HPGPKGDMGLTGPPGQPGPQGQKGEKGQCGEYPHR-- 219 Query: 791 FQPSQRTSASKLGALSLGSFNKPSSKDNLFGQSCLAALSTACQN--MIASLGAPNLNVTF 848 CL+++ A ++ +IA P LN + Sbjct: 220 --------------------------------ECLSSMPAALRSSQIIALKLLPLLN-SV 246 Query: 849 NKKNPPEGKRKLSQNETDGAAVAGNPGSDYFPGGTAP----GAPGPGGPSGTSSSGSKAS 904 PP KR+ Q E A++ G PG PG + P G PGP GP G Sbjct: 247 RLAPPPVIKRRTFQGEQSQASIQGPPGPPGPPGPSGPLGHPGLPGPMGPPGLP------- 299 Query: 905 GPPNPPAQGDGTSLSPNYTLESTSGNDGKP----VSGGGGRGRGRRKRDSGHVSPGTFFD 960 GPP P +GD + + + G G P G G K + G PGT + Sbjct: 300 GPPGP--KGD-PGIQGYHGRKGERGMPGMPGKHGAKGAPGIAVAGMKGEPG--IPGTKGE 354 Query: 961 KYSAAPDSGGAPGVSPGQQQASGAAVGGSSAGETRGAPTPHEKALTSPSWGKGAELLLGD 1020 K A S G PG+ GQ+ G A G+S G RG P P L P KG + G Sbjct: 355 K--GAEGSPGLPGLL-GQKGEKGDA--GNSIGGGRGEPGP--PGLPGPPGPKGEAGVDGQ 407 Query: 1021 -----QPDLIGSLDG-------GAKSDSSSPNVGEFASDEVSTSYANEDEVSSSSDNPQA 1068 QP G G K P GE + + A ++ + + P Sbjct: 408 VGPPGQPGDKGERGAAGEQGPDGPKGSKGEPGKGEMVDYNGNINEALQEIRTLALMGPPG 467 Query: 1069 LVKASRSPLVTGSPK------LPPRGVGAGEHGPKAPPPALGLGIMSNSTSTPDSYGGGG 1122 L P G P LP GE GP+ P +G G G Sbjct: 468 LPGQIGPPGAPGIPGQKGEIGLPGPPGHDGEKGPRGKPGDMGPPGPQGPPGKDGPPGVKG 527 Query: 1123 GPGHPGTPGLEQVRTPTSSSGAP 1145 GHPG+PG + + T +G+P Sbjct: 528 ENGHPGSPGEKGEKGETGQAGSP 550 Score = 58.5 bits (140), Expect = 4e-08 Identities = 148/576 (25%), Positives = 182/576 (31%), Gaps = 109/576 (18%) Query: 632 FSGPHPPPGDLLPRRMGGSGLPADCG-PHDPSLA---PPPPPGGSGVL----FRGP--LQ 681 F GP PG LP G G+P G P D L+ P PPG G F GP L Sbjct: 123 FQGPTGRPG--LPGDKGAIGMPGRVGSPGDAGLSIIGPRGPPGQPGTRGFPGFPGPIGLD 180 Query: 682 EPMRMPGEGHVPALPSPGLQFG--GSLGGLGQ---------LQSPGAGVG---------L 721 PG L P Q G G G GQ L S A + L Sbjct: 181 GKPGHPGPKGDMGLTGPPGQPGPQGQKGEKGQCGEYPHRECLSSMPAALRSSQIIALKLL 240 Query: 722 PSAASERRPPPPDFATSALGGQPGFPFGAAGRQSTPHSGPGVNSPPSAGGGGGSSGGGGG 781 P S R PPP G+ Q++ PG PP G G G G Sbjct: 241 PLLNSVRLAPPPVIKRRTFQGEQS--------QASIQGPPGPPGPPGPSGPLGHPGLPGP 292 Query: 782 GGAY----PPQPDFQPSQRTSASKLGALSL-GSFNKPSSKDNLFGQSCLAALSTACQNMI 836 G PP P P + + G + G K +K A A M Sbjct: 293 MGPPGLPGPPGPKGDPGIQGYHGRKGERGMPGMPGKHGAK---------GAPGIAVAGMK 343 Query: 837 ASLGAPNLNVTFNKKNPPEGKRKLSQNETDGAAVAGNPGSDYFPGGTAPGAPGPGGPSGT 896 G P + P L Q G A G PG PG PGP GP G Sbjct: 344 GEPGIPGTKGEKGAEGSPGLPGLLGQKGEKGDAGNSIGGGRGEPG--PPGLPGPPGPKGE 401 Query: 897 SSSGSKASGPPNPPAQGDGTSLSPNYTLESTSGNDGKPVSGGGGRGRGRRKRDSGHVSPG 956 + + GPP P + + G+ G+P G+G +G+++ Sbjct: 402 AGVDGQV-GPPGQPGDKGERGAAGEQGPDGPKGSKGEP-------GKGEMVDYNGNINEA 453 Query: 957 TFFDKYSAAPDSGGAPGVSPGQQQASGAAVGGSSAGETRGAPTPHEKALTSPSWGKGAEL 1016 + A G PG+ PGQ GA GE G P P KG Sbjct: 454 LQEIRTLALM---GPPGL-PGQIGPPGAPGIPGQKGEI-GLPGP-----PGHDGEKGPRG 503 Query: 1017 LLGDQ----PDLIGSLDG--GAKSDSSSPNVGEFASDEVSTSYAN---EDEVSSSSDNPQ 1067 GD P DG G K ++ P ++ T A E + NP Sbjct: 504 KPGDMGPPGPQGPPGKDGPPGVKGENGHPGSPGEKGEKGETGQAGSPGEKGEAGEKGNPG 563 Query: 1068 ALVKASRSPLVTGSPKLP-------PRGVGA-----------GEHGPKAPPPALGLGIMS 1109 A V P G P P P+G GE G + P LGL Sbjct: 564 AEVPGLPGP--EGPPGPPGLQGVPGPKGEAGLDGAKGEKGFQGEKGDRGP---LGLPGTP 618 Query: 1110 NSTSTPDSYGGGGGPGHPGTPGLEQVRTPTSSSGAP 1145 P G G G G PG+ PT ++G P Sbjct: 619 GPIGVPGPAGPKGERGSKGDPGM---TGPTGAAGLP 651 Score = 54.7 bits (130), Expect = 6e-07 Identities = 136/557 (24%), Positives = 178/557 (31%), Gaps = 105/557 (18%) Query: 492 PGLPGEFTPPVPDSFPSGPPLQHPAPDHQSLQQQQQQQQQQQQQQQQQQQQQQQQQQQQR 551 PG PG P D +GPP Q P P Q Q+ ++ Q + ++ R Sbjct: 183 PGHPG----PKGDMGLTGPPGQ-PGP-------QGQKGEKGQCGEYPHRECLSSMPAALR 230 Query: 552 QNAALMIKQMASRNQQQRLRQPNLAQLGHPGDVGQGGLVHGGPVGGLAQPNFEREGGSTG 611 + + +K + N + P + + G+ Q + GP G P G S Sbjct: 231 SSQIIALKLLPLLNSVRLAPPPVIKRRTFQGEQSQASIQ--GPPGPPGPP-----GPSGP 283 Query: 612 AGRLGTFEQQAPHLAQESAWFSGPHPPPGDL----LPRRMGGSGLPADCGPHDPSLAPPP 667 G G P GP P GD R G G+P G H AP Sbjct: 284 LGHPGLPGPMGP------PGLPGPPGPKGDPGIQGYHGRKGERGMPGMPGKHGAKGAP-- 335 Query: 668 PPGGSGVLFRGPLQEPMRMPGEGHVPALPSPGLQFGGSLGGLGQLQSPGAGVGLPSAASE 727 G+ G EP +G A SPGL G LG G+ G +G Sbjct: 336 -----GIAVAGMKGEPGIPGTKGEKGAEGSPGLP--GLLGQKGEKGDAGNSIG----GGR 384 Query: 728 RRPPPPDFATSALGGQPGFPFGAAG--RQSTPHSGPGVNSPPSAGGGGGSSGGGGGGG-- 783 P PP L G PG P G AG Q P PG A G G G G G Sbjct: 385 GEPGPP-----GLPGPPG-PKGEAGVDGQVGPPGQPGDKGERGAAGEQGPDGPKGSKGEP 438 Query: 784 AYPPQPDFQPSQRTSASKLGALSL-------GSFNKPSSKDNLFGQSCLAAL-------- 828 D+ + + ++ L+L G P + + GQ L Sbjct: 439 GKGEMVDYNGNINEALQEIRTLALMGPPGLPGQIGPPGAP-GIPGQKGEIGLPGPPGHDG 497 Query: 829 STACQNMIASLGAPNLNVTFNKKNPPEGK----------RKLSQNETDGAAVAGNPGS-- 876 + +G P K PP K K + ET A G G Sbjct: 498 EKGPRGKPGDMGPPGPQGPPGKDGPPGVKGENGHPGSPGEKGEKGETGQAGSPGEKGEAG 557 Query: 877 -DYFPGGTAPGAPGPGGPSGTSSSGSKASGPPNPPAQG--DGTSLSPNYT---------- 923 PG PG PGP GP G G P P + DG + Sbjct: 558 EKGNPGAEVPGLPGPEGPPGPPG----LQGVPGPKGEAGLDGAKGEKGFQGEKGDRGPLG 613 Query: 924 LESTSGNDGKPVSGGGGRGRGRRKRDSGHVSPGTFFDKYSAAPDSGGAPG--VSPGQQQA 981 L T G G P G +G K D G P + P G PG + G++ Sbjct: 614 LPGTPGPIGVP-GPAGPKGERGSKGDPGMTGP----TGAAGLPGLHGPPGDKGNRGERGK 668 Query: 982 SGAAVGGSSAGETRGAP 998 G+ G+ +GAP Sbjct: 669 KGSRGPKGDKGD-QGAP 684 Score = 52.0 bits (123), Expect = 4e-06 Identities = 101/381 (26%), Positives = 126/381 (33%), Gaps = 48/381 (12%) Query: 579 GHPGDVGQGGLVHGGPVGGLAQPNFER--EGGSTGAGR--LGTFEQQAPHLAQESAWFSG 634 G PG G+ G + GL E+ G S G GR G P + A G Sbjct: 347 GIPGTKGEKGAEGSPGLPGLLGQKGEKGDAGNSIGGGRGEPGPPGLPGPPGPKGEAGVDG 406 Query: 635 PHPPPGDLLPRRMGGSGLPADCGPHDPSLAPPPPPGGSGVLFRGPLQEPMRMPGEGHVPA 694 PPG P G G + GP P + P G V + G + E ++ E A Sbjct: 407 QVGPPGQ--PGDKGERGAAGEQGPDGPKGSKGEPGKGEMVDYNGNINEALQ---EIRTLA 461 Query: 695 LPSPGLQFGGSLGGLGQLQSPGAGVGLPSAASERRPPPPDFATSALG--GQPGFPFGAAG 752 L P G GQ+ PGA G+P E P P G G+PG G G Sbjct: 462 LMGPP-------GLPGQIGPPGAP-GIPGQKGEIGLPGPPGHDGEKGPRGKPG-DMGPPG 512 Query: 753 RQSTPHSGPGVNSPPSAGGGGGSSGGGGGGGAYPPQPDF-QPSQRTSASKLGALSLGSFN 811 P PG + PP G G G G G P ++ A + G N Sbjct: 513 ----PQGPPGKDGPPGVKGENGHPGSPGEKGEKGETGQAGSPGEKGEAGEKG-------N 561 Query: 812 KPSSKDNLFGQSCLAALSTACQNMIASLGAPNLNVTFNKKN--PPEGKR-KLSQNETDG- 867 + L G Q + G L+ +K +G R L T G Sbjct: 562 PGAEVPGLPGPEGPPG-PPGLQGVPGPKGEAGLDGAKGEKGFQGEKGDRGPLGLPGTPGP 620 Query: 868 ------AAVAGNPGSDYFPGGTAP----GAPGPGGPSGTSSS-GSKASGPPNPPAQGDGT 916 A G GS PG T P G PG GP G + G + P G Sbjct: 621 IGVPGPAGPKGERGSKGDPGMTGPTGAAGLPGLHGPPGDKGNRGERGKKGSRGPKGDKGD 680 Query: 917 SLSPNYTLESTSGNDGKPVSG 937 +P G DG PV G Sbjct: 681 QGAPGLDAPCPLGEDGLPVQG 701 Score = 35.8 bits (81), Expect = 0.28 Identities = 92/355 (25%), Positives = 121/355 (34%), Gaps = 45/355 (12%) Query: 43 GPPGPVDPAMSALGEPPILGMNMEPYGFHARGHSELHAGGLQAQP-VHGFFG--GQQPHH 99 GPPGP P+ LG P + G M P G G + P + G+ G G++ Sbjct: 273 GPPGPPGPS-GPLGHPGLPGP-MGPPGLPG-------PPGPKGDPGIQGYHGRKGERGMP 323 Query: 100 GHPGSHHPHQHHPHFG--GNFGGPD-PGASCLHGGRLLGYGGAAGGLGSQPPFAEGYEHM 156 G PG H + P G G P PG G G G G LG + + + Sbjct: 324 GMPGKHGA-KGAPGIAVAGMKGEPGIPGTKGEKGAE--GSPGLPGLLGQKGEKGDAGNSI 380 Query: 157 AESQGPESFGPQRPGNLPDFHSSGASSHAVPAPCLPLDQSPNRAASFHGLPSSSGSDSHS 216 +G E P PG +G P P P D+ AA G GS Sbjct: 381 GGGRG-EPGPPGLPGPPGPKGEAGVDGQVGP-PGQPGDKGERGAAGEQGPDGPKGSKGEP 438 Query: 217 LEPRRVTNQGAVDSLEYNYPGEAPSGHFDMFSPSDSEGQL-PHYAAGRQVPGGAFPGASA 275 + V G ++ A G P GQ+ P A G +PG G Sbjct: 439 GKGEMVDYNGNINEALQEIRTLALMG------PPGLPGQIGPPGAPG--IPGQK--GEIG 488 Query: 276 MPRAAGMVGLSKMHAQPPQQQPQQQQQPQQQQQQHGVFFERF---SGARKMPVGLEPSVG 332 +P G G +P P Q P + GV E S K G G Sbjct: 489 LPGPPGHDGEKGPRGKPGDMGPPGPQGPPGKDGPPGVKGENGHPGSPGEKGEKGETGQAG 548 Query: 333 SRHPLMQPPQQAPPPPQQQPPQQPPQQQPPPPPGLLVRQNSCPPALPRPQQGEAG 387 S + ++ P + P P + PP PPGL +P P +GEAG Sbjct: 549 SPGEKGEAGEKGNPGAEV--PGLPGPEGPPGPPGL--------QGVPGP-KGEAG 592 >gi|239754955 PREDICTED: similar to COL22A1 protein [Homo sapiens] Length = 1073 Score = 90.5 bits (223), Expect = 1e-17 Identities = 168/637 (26%), Positives = 208/637 (32%), Gaps = 123/637 (19%) Query: 579 GHPGDVGQGGL--------VHG-----GPVGGLAQPNFEREGGSTGA-------GRLGTF 618 G PG+ G+ GL V G G G L P + + G G G GT Sbjct: 277 GRPGEKGEAGLPGAPGFPGVRGEKGDQGEKGELGLPGLKGDRGEKGEAGPAGPPGLPGTT 336 Query: 619 EQQAPHLAQESAWFSGPHPPPGDL-LPRRMGGSGLPADCGPHDPSLAPPPPPGGSGVLFR 677 PH GP GD LP G G P + GP P+ PPG G Sbjct: 337 SLFTPHPRMPGE--QGPKGEKGDPGLPGEPGLQGRPGELGPQGPT----GPPGAKGQEGA 390 Query: 678 GPLQEPMRMPGE-GHVPALPSPGLQFGGSLGGLGQLQSPGAGV--GLPSAASERRPPPPD 734 PG GHV A P P GS+G G +PG G AA E P P Sbjct: 391 HGAPGAAGNPGAPGHVGA-PGPSGP-PGSVGAPGLRGTPGKDGERGEKGAAGEEGSPGP- 447 Query: 735 FATSALGGQPGFPFGAAGRQSTPHSG----PGVNSP---------PSAGGGGGSSGGGGG 781 G PG P G G+ G PG+ P P G GS G G Sbjct: 448 VGPRGDPGAPGLP-GPPGKGKDGEPGLRGSPGLPGPLGTKGDRGAPGIPGSPGSRGDPGI 506 Query: 782 GGAYPPQPDFQPSQRTSASKLGALSLGSFNKPSSKDNLFGQSCLAALSTACQNMIASLGA 841 G A PP P P + S G P+ +D L + LS N++A Sbjct: 507 GVAGPPGPSGPPGDKGSPGSRGLPGFPGPQGPAGRDGLS-----SLLSPGDINLLAK--- 558 Query: 842 PNLNVTFNKKNPPEGKRKLSQNETDGAAVAGNPGSDYFPG--GTA--PGAPGPGGPSGTS 897 +V + P G L + D V G PG + G G A PG PGP G +G Sbjct: 559 ---DVCNDCPPGPPGLPGLPGFKGD-KGVPGKPGREGTEGKKGEAGPPGLPGPPGIAGPQ 614 Query: 898 SS----------GSKAS-------------GPPNPPAQGDGTSLSPNYTLESTSGNDGKP 934 S G K G P PP + ++ + G +G P Sbjct: 615 GSQGERGADGEVGQKGDQGHPGVPGFMGPPGNPGPPGADGIAGAAGPPGIQGSPGKEGPP 674 Query: 935 VSGG-----GGRGR-GRRKRDSGHVSPGTFFDKYSAAPDSGGAPGVSPGQQQASGAAVGG 988 G G G G+ RD PG P G PG+ PG + A G Sbjct: 675 GPQGPSGLPGIPGEEGKEGRDGKPGPPGE--------PGKAGEPGL-PGPEGARGPPGFK 725 Query: 989 SSAGETRGAPTPHEKALTSPSWGKGAELLLGDQPDLIGSLDGGAKSDSSSPNVGEFASDE 1048 G++ GAP P G+ + L Q L G K + P + Sbjct: 726 GHTGDS-GAPGPR---------GESGAMGLPGQEGLPG------KDGDTGPTGPQGPQGP 769 Query: 1049 VSTSYANEDEVSSSSDNPQALVKASRSPLVTGSPKLPPRGVGAGEHGPKAPPPALGLGIM 1108 N S P S GSP LP G GP+ PP G + Sbjct: 770 RGPPGKNGSPGSPGEPGPSGTPGQKGSKGENGSPGLP------GFLGPRGPPGEPGEKGV 823 Query: 1109 SNSTSTPDSYGGGGGPGHPGTPGLEQVRTPTSSSGAP 1145 P G G G G PG++ + P G P Sbjct: 824 PGKEGVPGKPGEPGFKGERGDPGIKGDKGPPGGKGQP 860 Score = 80.5 bits (197), Expect = 1e-14 Identities = 164/612 (26%), Positives = 195/612 (31%), Gaps = 155/612 (25%) Query: 573 PNLAQL-GHPGDVGQGGLVHG----GPVG--GLA-QPNFEREGGSTGAGRLGTFEQQAPH 624 P L QL G PG+ G+ GL G +G GLA +P + E G GA P Sbjct: 243 PGLKQLNGEPGERGEDGLPGKPGLRGEIGEQGLAGRPGEKGEAGLPGAPGF-------PG 295 Query: 625 LAQESAWFSGPHPPPGDL-LPRRMGGSGLPADCGPHDPSLAPPPPPGGSGVLFRGPLQEP 683 + E G G+L LP G G + GP PP PG + + P Sbjct: 296 VRGEK----GDQGEKGELGLPGLKGDRGEKGEAGP----AGPPGLPGTTSLFTPHPRMPG 347 Query: 684 MRMP-GEGHVPALPS-PGLQFG-GSLGGLGQLQSPGA-----GVGLPSAASERRPPPPDF 735 + P GE P LP PGLQ G LG G PGA G P AA Sbjct: 348 EQGPKGEKGDPGLPGEPGLQGRPGELGPQGPTGPPGAKGQEGAHGAPGAA---------- 397 Query: 736 ATSALGGQPGFP--FGAAGRQSTPHS--GPGVNSPPSAGGGGGSSGGGGGGGAYPPQPDF 791 G PG P GA G P S PG+ P G G G G G+ P P Sbjct: 398 ------GNPGAPGHVGAPGPSGPPGSVGAPGLRGTPGKDGERGEKGAAGEEGS--PGPVG 449 Query: 792 QPSQRTSASKLGALSLGSFNKPSSKDNLFGQSCLAALSTACQNMIASLGAPNLNVTFNKK 851 + G G +P + G+P L K Sbjct: 450 PRGDPGAPGLPGPPGKGKDGEPGLR-----------------------GSPGLPGPLGTK 486 Query: 852 NPPEGKRKLSQNETDGAAVAGNPGSDYFPGGTAPGAPGPGGPSGTSSSGSKASGP----P 907 + + G+PGS PG G PGP GP G S P P Sbjct: 487 G-----------DRGAPGIPGSPGSRGDPGIGVAGPPGPSGPPGDKGSPGSRGLPGFPGP 535 Query: 908 NPPAQGDGTS--LSPN--YTLESTSGNDGKPVSGGGGRGRGRRKRDSGHVSPGTFFDKYS 963 PA DG S LSP L ND P G PG DK Sbjct: 536 QGPAGRDGLSSLLSPGDINLLAKDVCNDCPPGPPGLPG------------LPGFKGDK-- 581 Query: 964 AAPDSGGAPGVSPGQQQASGAAVGGSSAGETRGAPTPHEKALTSPSWGKGAELLLGDQPD 1023 G PG PG++ G GE P + P +G G+ Sbjct: 582 ------GVPG-KPGREGTEG------KKGEAGPPGLPGPPGIAGPQGSQGERGADGEV-- 626 Query: 1024 LIGSLDGGAKSDSSSPNVGEFASDEVSTSYANEDEVSSSSDNPQALVKASRSPLVTGSP- 1082 G K D P V F + D ++ A+ P + GSP Sbjct: 627 -------GQKGDQGHPGVPGFMGPPGNPGPPGADGIAG----------AAGPPGIQGSPG 669 Query: 1083 -KLPPRGVGAGEHGPKAPPPALGLGIMSNSTSTPDSYGGGGGPGHPGTPGLEQVRTP--- 1138 + PP G GP P G P G G G PG PG E R P Sbjct: 670 KEGPP-----GPQGPSGLPGIPGEEGKEGRDGKPGPPGEPGKAGEPGLPGPEGARGPPGF 724 Query: 1139 ---TSSSGAPPP 1147 T SGAP P Sbjct: 725 KGHTGDSGAPGP 736 Score = 74.3 bits (181), Expect = 7e-13 Identities = 156/624 (25%), Positives = 194/624 (31%), Gaps = 95/624 (15%) Query: 579 GHPGDVGQGGLVHGGPVGGLAQPNFEREGGSTG-------AGRLGTFEQQAPHLAQESAW 631 G PG VG G GP G + P G G AG G+ P + Sbjct: 401 GAPGHVGAPG--PSGPPGSVGAPGLRGTPGKDGERGEKGAAGEEGSPGPVGPRGDPGAPG 458 Query: 632 FSGPHPPPGDLLPRRMGGSGLPADCGPHDPSLAP-----PPPPGGSGVLFRGPLQEPMRM 686 GP D P G GLP G AP P G G+ GP P Sbjct: 459 LPGPPGKGKDGEPGLRGSPGLPGPLGTKGDRGAPGIPGSPGSRGDPGIGVAGP-PGPSGP 517 Query: 687 PGEGHVPA---LPS-PGLQFGGSLGGLGQLQSPGAGVGLPSAASERRPPPPDFATSALGG 742 PG+ P LP PG Q GL L SPG L PP P L G Sbjct: 518 PGDKGSPGSRGLPGFPGPQGPAGRDGLSSLLSPGDINLLAKDVCNDCPPGPP----GLPG 573 Query: 743 QPGFPF-----GAAGRQSTPHSG-----PGVNSPPSAGGGGGSSGGGGGGG--------A 784 PGF G GR+ T PG+ PP G GS G G G Sbjct: 574 LPGFKGDKGVPGKPGREGTEGKKGEAGPPGLPGPPGIAGPQGSQGERGADGEVGQKGDQG 633 Query: 785 YPPQPDFQ--------PSQRTSASKLGALSL-GSFNK--------PSSKDNLFGQSCLAA 827 +P P F P A G + GS K PS + G+ Sbjct: 634 HPGVPGFMGPPGNPGPPGADGIAGAAGPPGIQGSPGKEGPPGPQGPSGLPGIPGEEGKEG 693 Query: 828 LS--TACQNMIASLGAPNLNVTFNKKNPPEGKRKLSQNETDG----AAVAGNPGSDYFPG 881 G P L + PP K + G + G PG + PG Sbjct: 694 RDGKPGPPGEPGKAGEPGLPGPEGARGPPGFKGHTGDSGAPGPRGESGAMGLPGQEGLPG 753 Query: 882 GTAPGAP-GPGGPSGTSSSGSKASGPPNPPAQGDGTSLSPNYTLESTSGNDGKPVSGG-- 938 P GP GP G K +G P P + G S +P + + G +G P G Sbjct: 754 KDGDTGPTGPQGPQGPRGPPGK-NGSPGSPGE-PGPSGTPGQ--KGSKGENGSPGLPGFL 809 Query: 939 GGRGRGRRKRDSGHVSPGTFFDKYSAAPDSGGAPGVS-----PGQQQASGAAVGGSSAGE 993 G RG + G PG P G PG PG + G G G+ Sbjct: 810 GPRGPPGEPGEKG--VPGK-----EGVPGKPGEPGFKGERGDPGIKGDKGPPGGKGQPGD 862 Query: 994 TRGAPTPHEKALTSPSWGKGAELLLGD-----QPDLIGSLDGGAKSDSSSPNVGEFASDE 1048 L P G +G QP G ++ + E + Sbjct: 863 PGIPGHKGHTGLMGPQGLPGENGPVGPPGPPGQPGFPGLRGESPSMETLRRLIQEELGKQ 922 Query: 1049 VSTSYANEDEVSSSSDNPQALVKASRSPLVTGSPKLPPRGVGAGEHGPKAPPPALGLGIM 1108 + T A + P A +K+S+ G P P + G GP P G G + Sbjct: 923 LETRLAY-----LLAQMPPAYMKSSQGR--PGPPGPPGKDGLPGRAGPMGEPGRPGQGGL 975 Query: 1109 SNSTSTPDSYGGGGGPGHPGTPGL 1132 + G G G PG PG+ Sbjct: 976 EGPSGPIGPKGERGAKGDPGAPGV 999 Score = 67.8 bits (164), Expect = 7e-11 Identities = 104/401 (25%), Positives = 134/401 (33%), Gaps = 82/401 (20%) Query: 579 GHPGDVGQGGLVHGGPVGGLAQPNFEREGGSTGA-------GRLGTFEQQAPHLAQESAW 631 G PG G+ GL GP G P F+ G +GA G +G Q+ Sbjct: 702 GEPGKAGEPGLP--GPEGARGPPGFKGHTGDSGAPGPRGESGAMGLPGQEGLPGKDGDTG 759 Query: 632 FSGPHPPPGDLLPRRMGGS-GLPADCGPHDP-----SLAPPPPPGGSGVLF-RGPLQEPM 684 +GP P G P GS G P + GP S PG G L RGP EP Sbjct: 760 PTGPQGPQGPRGPPGKNGSPGSPGEPGPSGTPGQKGSKGENGSPGLPGFLGPRGPPGEPG 819 Query: 685 R--MPGEGHVPALPS-PGLQFGGSLGGLGQLQSPGAGVGLPSAASERRPPPPDFATSALG 741 +PG+ VP P PG + G+ + P G G P Sbjct: 820 EKGVPGKEGVPGKPGEPGFKGERGDPGIKGDKGPPGGKGQP------------------- 860 Query: 742 GQPGFPFGAAGRQST--PHSGPGVNSPPSAGGGGGSSGGGGGGGAYPP--------QPDF 791 G PG P G G P PG N P G G G G G P Q + Sbjct: 861 GDPGIP-GHKGHTGLMGPQGLPGENGPVGPPGPPGQPGFPGLRGESPSMETLRRLIQEEL 919 Query: 792 QPSQRTSASKLGALSLGSFNK----------PSSKDNLFGQSCLAALSTACQNMIASLGA 841 T + L A ++ K P KD L G++ + G Sbjct: 920 GKQLETRLAYLLAQMPPAYMKSSQGRPGPPGPPGKDGLPGRA----------GPMGEPGR 969 Query: 842 PNLNVTFNKKNP--PEGKRKLS----------QNETDGAAVAGNPGSDYFPGGTAPGAPG 889 P P P+G+R + E + G PG + PG PG Sbjct: 970 PGQGGLEGPSGPIGPKGERGAKGDPGAPGVGLRGEMGPPGIPGQPGEPGYAKDGLPGIPG 1029 Query: 890 PGGPSGTSSSGSKASGPPNPPAQGDGTSLSPNYTLESTSGN 930 P G +G + GPP PP Q D + + +L + GN Sbjct: 1030 PQGETGPAGHPG-LPGPPGPPGQCDPSQCAYFASLAARPGN 1069 Score = 58.5 bits (140), Expect = 4e-08 Identities = 164/704 (23%), Positives = 228/704 (32%), Gaps = 149/704 (21%) Query: 43 GPPGPV----DPAMSALGEPPILGMNMEPYGFHARGHSELHAGGLQAQPVHGFFG--GQQ 96 G PGPV DP L PP G + EP GL+ P G G G + Sbjct: 443 GSPGPVGPRGDPGAPGLPGPPGKGKDGEP--------------GLRGSP--GLPGPLGTK 486 Query: 97 PHHGHPGSHHPHQHHPHFGGNFGGPDPGASCLHGGRLLGYGGAAGGLGSQPPFAEGYEHM 156 G PG P G+ G DPG +G G G G PP +G Sbjct: 487 GDRGAPGI-------PGSPGSRG--DPG---------IGVAGPPGPSG--PPGDKG---S 523 Query: 157 AESQGPESF-GPQRPGN---LPDFHSSGASSHAVPAPCLPLDQSPNRAASFHGLPSSSGS 212 S+G F GPQ P L S G + C + P GLP G Sbjct: 524 PGSRGLPGFPGPQGPAGRDGLSSLLSPGDINLLAKDVC---NDCPPGPPGLPGLPGFKGD 580 Query: 213 DSHSLEPRRVTNQGAVDSLEYNYPG-EAPSGHFDMFSPSDSEGQ---------------- 255 +P R +G E PG P G + P S+G+ Sbjct: 581 KGVPGKPGREGTEGKKG--EAGPPGLPGPPG---IAGPQGSQGERGADGEVGQKGDQGHP 635 Query: 256 -LPHYAAGRQVPGGAFPGASAMPRAAGMVGLSKMHAQPPQQQPQQQQQPQQQQQQHGVFF 314 +P + PG PGA + AAG G+ P ++ P Q P G Sbjct: 636 GVPGFMGPPGNPGP--PGADGIAGAAGPPGIQ---GSPGKEGPPGPQGPSGLPGIPGEEG 690 Query: 315 ERFSGARKMPVGLEPSVGSRHPLMQPPQQAPPPPQQQ----------PPQQPPQQQPPPP 364 + + P G G P + P+ A PP + P + P Sbjct: 691 KEGRDGKPGPPGEPGKAGE--PGLPGPEGARGPPGFKGHTGDSGAPGPRGESGAMGLPGQ 748 Query: 365 PGLLVRQNSCPPALPRPQQGEAGTPSGGLQDGGPMLPSQHAQFEYPIHRLENRSMHPYSE 424 GL + P P+ QG G P ++G P P + P + Sbjct: 749 EGLPGKDGDTGPTGPQGPQGPRGPPG---KNGSPGSPGEPGPSGTPGQKGSKGENGSPGL 805 Query: 425 PVFSMQHPPPQQAPNQRL---QHFDAPPYMNVAKRPRFDFPGSAGVDRCASWNGSMHNGA 481 P F PP + + + + P K R D PG G G + Sbjct: 806 PGFLGPRGPPGEPGEKGVPGKEGVPGKPGEPGFKGERGD-PGIKGDKGPPGGKGQPGDPG 864 Query: 482 LDNH------LSPSAYPGLPGEFTPPVPDSFPSGPPLQHPAPDHQSLQQQQQQQQQQQQQ 535 + H + P PG G PP P P P L+ +P ++L++ Q++ +Q + Sbjct: 865 IPGHKGHTGLMGPQGLPGENGPVGPPGPPGQPGFPGLRGESPSMETLRRLIQEELGKQLE 924 Query: 536 QQQQQQQQQQQQQQQRQNAALMIKQMASRNQQQRLRQPNLAQLGHPGDVGQGGLVHGGPV 595 + A ++ QM + +P G PG G+ GL G Sbjct: 925 TR----------------LAYLLAQMPPAYMKSSQGRP-----GPPGPPGKDGL--PGRA 961 Query: 596 GGLAQPNFEREGGSTG-AGRLGTFEQQAPHLAQESAWFSGPHPPPGDLLPRRMGGSGLPA 654 G + +P +GG G +G +G ++ G PG L MG G+P Sbjct: 962 GPMGEPGRPGQGGLEGPSGPIGPKGERGA---------KGDPGAPGVGLRGEMGPPGIPG 1012 Query: 655 DCGPHDPSLAPPPPPGGSGVLFRGPLQEPMRMPGEGHVPALPSP 698 P +P A PG G P G P LP P Sbjct: 1013 Q--PGEPGYAKDGLPGIPG---------PQGETGPAGHPGLPGP 1045 Score = 50.8 bits (120), Expect = 8e-06 Identities = 133/550 (24%), Positives = 178/550 (32%), Gaps = 83/550 (15%) Query: 626 AQESAWFSGPHPPPGDLLPRRMGGSGLPADCGPHDPSLAPPPP------PGGSGVLF--- 676 ++ES GP P + + + G+ CG + S+ P P G+G F Sbjct: 164 SRESLDLLGPRTDPWENVDQGAQGA-----CGRGNTSVLPSSVAPQCSMPKGTGHEFSAA 218 Query: 677 ---RGPLQEPMRMPGEGHVPALPSPGL-QFGGSLGGLGQLQSPGAGVGLPSAASER--RP 730 +GP + + A +PGL Q G G G+ PG GL E+ Sbjct: 219 LGTQGPADQRADARASCILAAKTAPGLKQLNGEPGERGEDGLPGKP-GLRGEIGEQGLAG 277 Query: 731 PPPDFATSALGGQPGFPFGAAGRQSTPHSGPGVNSPPSAGGGG--GSSGGGGGGGAYPPQ 788 P + + L G PGFP G G + + P G G G +G G G Sbjct: 278 RPGEKGEAGLPGAPGFP-GVRGEKGDQGEKGELGLPGLKGDRGEKGEAGPAGPPGLPGTT 336 Query: 789 PDFQPSQRTSASKLGALSLGSFNKPSSKDNLFGQSCLAALSTACQNMIASLGAPNLNVTF 848 F P R + G P Q LG Sbjct: 337 SLFTPHPRMPGEQGPKGEKGDPGLPGEP--------------GLQGRPGELGPQG----- 377 Query: 849 NKKNPPEGKRKLSQNETDGAAVAGNPGSDYFPGGTAPGAPGPGGPSGTSSSGSKASGPPN 908 PP K + + GAA GNPG+ PG GAPGP GP G+ + P Sbjct: 378 -PTGPPGAKGQEGAHGAPGAA--GNPGA---PGHV--GAPGPSGPPGSVGAPGLRGTPGK 429 Query: 909 PPAQGD----GTSLSPNYTLESTSGNDGKPVSGG--GGRGRGRRKRDSGHVSPGTFFDKY 962 +G+ G SP G G P + G G G+G+ SPG Sbjct: 430 DGERGEKGAAGEEGSPGPV-----GPRGDPGAPGLPGPPGKGKDGEPGLRGSPG--LPGP 482 Query: 963 SAAPDSGGAPGV--SPGQQQASGAAVGGSSAGETRGAPTPHEKALTSPSWGKGAELLLGD 1020 GAPG+ SPG + G V G P P + P KG+ G Sbjct: 483 LGTKGDRGAPGIPGSPGSRGDPGIGVAGP--------PGP-----SGPPGDKGSPGSRG- 528 Query: 1021 QPDLIGSLDGGAKSDSSSPNVGEFASDEVSTSYANEDEVSSSSDNPQALVKASRSPLVTG 1080 P G G A D S + + ++ N+ K + V G Sbjct: 529 LPGFPGP-QGPAGRDGLSSLLSPGDINLLAKDVCNDCPPGPPGLPGLPGFKGDKG--VPG 585 Query: 1081 SPKLPPRGVGAGEHGPKAPPPALGLGIMSNSTSTPDSYGGGGGPGHPGTPGLEQVRTPTS 1140 P GE GP P G+ S + G G G G PG+ P Sbjct: 586 KPGREGTEGKKGEAGPPGLPGPPGIAGPQGSQGERGADGEVGQKGDQGHPGVPGFMGPPG 645 Query: 1141 SSGAPPPDEI 1150 + G P D I Sbjct: 646 NPGPPGADGI 655 Score = 37.0 bits (84), Expect = 0.13 Identities = 72/272 (26%), Positives = 91/272 (33%), Gaps = 52/272 (19%) Query: 135 GYGGAAGGLGSQPPFAE-GYEHMAESQGPES-FGPQRPGNLPDFHSSGASSHAVPAPCLP 192 G+ G G G Q E G + +G + GP P LP G +S P P +P Sbjct: 292 GFPGVRGEKGDQGEKGELGLPGLKGDRGEKGEAGPAGPPGLP-----GTTSLFTPHPRMP 346 Query: 193 LDQSPNRAASFHGLPSSSGSDSHSLEPRRVTNQGAVDSLEYNYPGEAPSGHFDMFSPSDS 252 +Q P GLP G PGE P Sbjct: 347 GEQGPKGEKGDPGLPGEPGLQGR--------------------PGE--------LGPQGP 378 Query: 253 EGQLPHYAAGRQVPGGAFPGASAMPRAAGMVGLSKMHAQPPQQQPQQQQQPQQQQQQHGV 312 G P A G++ GA PGA+ P A G VG A P P P + G Sbjct: 379 TG--PPGAKGQEGAHGA-PGAAGNPGAPGHVG-----APGPSGPPGSVGAPGLR----GT 426 Query: 313 FFERFSGARKMPVGLEPSVGSRHPLMQPPQQA-PPPPQQQPPQQPPQQQPPPPPGLL-VR 370 + K G E S G P P P PP + +P + P PG L + Sbjct: 427 PGKDGERGEKGAAGEEGSPGPVGPRGDPGAPGLPGPPGKGKDGEPGLRGSPGLPGPLGTK 486 Query: 371 QNSCPPALPRPQQGEAGTPSGGLQDGGPMLPS 402 + P +P G G P G+ GP PS Sbjct: 487 GDRGAPGIP-GSPGSRGDP--GIGVAGPPGPS 515 Score = 36.6 bits (83), Expect = 0.16 Identities = 81/347 (23%), Positives = 114/347 (32%), Gaps = 26/347 (7%) Query: 862 QNETDGAAVA-GNPGSDYFPGGTAPGAPGPGGPSGTSSSGSKASGPPNPPAQGDGTSLSP 920 +N GA A G + P AP P G S+ GP + A + + Sbjct: 179 ENVDQGAQGACGRGNTSVLPSSVAPQCSMPKGTGHEFSAALGTQGPADQRADARASCILA 238 Query: 921 NYTLESTSGNDGKPVSGG--GGRGRGRRKRDSGHVS-PGTFFDKYSAA-PDSGGAPGV-- 974 T +G+P G G G+ + + G G +K A P + G PGV Sbjct: 239 AKTAPGLKQLNGEPGERGEDGLPGKPGLRGEIGEQGLAGRPGEKGEAGLPGAPGFPGVRG 298 Query: 975 SPGQQQASGAAVGGSSAGETRGAPTPHEKALTSPSWGKGAELLLGDQPDLIGSLDGGAKS 1034 G Q G +G RG E P G L P + G + G K Sbjct: 299 EKGDQGEKGE-LGLPGLKGDRGEKG--EAGPAGPPGLPGTTSLFTPHPRMPG--EQGPKG 353 Query: 1035 DSSSPNV-GEFASDEVSTSYANEDEVSSSSDNPQALVKASRSPLVTGSPKLPPRGVGAGE 1093 + P + GE + Q A +P G+P P G Sbjct: 354 EKGDPGLPGEPGLQGRPGELGPQGPTGPPGAKGQE--GAHGAPGAAGNPGAPGH---VGA 408 Query: 1094 HGPKAPPPALGLGIMSNSTSTPDSYGGGGGPGHPGTPGLEQVRTPTSSSGAPPPDEIHPL 1153 GP PP ++G + + G G G G+PG R + G P P P Sbjct: 409 PGPSGPPGSVGAPGLRGTPGKDGERGEKGAAGEEGSPGPVGPRGDPGAPGLPGP----PG 464 Query: 1154 EILQAQIQLQRQQFSISEDQPLGLKGGKKGECAVGASGAQNGDSELG 1200 + + L+ S PLG K G +G + S GD +G Sbjct: 465 KGKDGEPGLRG---SPGLPGPLGTK-GDRGAPGIPGSPGSRGDPGIG 507 >gi|55750053 atrophin-1 [Homo sapiens] Length = 1190 Score = 89.0 bits (219), Expect = 3e-17 Identities = 150/556 (26%), Positives = 190/556 (34%), Gaps = 95/556 (17%) Query: 57 EPPILGMNMEPYGFHARGHSELHAGG----LQAQPVHGFFGGQQPHHGHP--GSHHPHQH 110 EPP M P G H +L+ GG L P+ GG G P G HP Sbjct: 199 EPPTSRMFQAPPGAPPP-HPQLYPGGTGGVLSGPPMGPKGGGAASSVGGPNGGKQHPPPT 257 Query: 111 HPHF--------------------GGNFGGPDPGASCLH---------GGRLLGYGGAAG 141 P GGN P A+ H R L A+ Sbjct: 258 TPISVSSSGASGAPPTKPPTTPVGGGNLPSAPPPANFPHVTPNLPPPPALRPLNNASASP 317 Query: 142 -GLGSQP-PFAEGYEH-MAESQGPESFGPQR-PGNLPDFHSSGASSHAVPAPCLPLDQSP 197 GLG+QP P H M + G GP++ P P HS +S + PAP + S Sbjct: 318 PGLGAQPLPGHLPSPHAMGQGMGGLPPGPEKGPTLAPSPHSLPPASSSAPAPPMRFPYSS 377 Query: 198 NRAASFHGLPSSSGSDSHSLEPRRVTNQGAVDSLEYNYP-------GEAPSGHFDMFSPS 250 + ++S SSS S S S P + A+ S +++P P + PS Sbjct: 378 SSSSSA-AASSSSSSSSSSASPFPASQ--ALPSYPHSFPPPTSLSVSNQPPKYTQPSLPS 434 Query: 251 D---SEGQLPHYAAGRQV------PGGAFPGASAMPRAAGMVGLSKMHAQPPQQQPQQQQ 301 S+G P GR + PG P A A V H Q QQQ QQQQ Sbjct: 435 QAVWSQGPPPPPPYGRLLANSNAHPGPFPPSTGAQSTAHPPVSTHHHHHQQQQQQQQQQQ 494 Query: 302 QPQQQQQQH---------GVF---FERFSGARKMPVGLEPSVGSRHPLMQPPQQAPPPPQ 349 Q QQQQQQH G F E S P + PS+GS P P PPP Sbjct: 495 QQQQQQQQHHGNSGPPPPGAFPHPLEGGSSHHAHPYAMSPSLGSLRPYPPGPAHLPPPHS 554 Query: 350 QQPPQQPPQQQPPPPPGL----LVRQNSCPPALPRPQQGEAGTPSGGLQDGGPMLPSQHA 405 Q Q PP Q S P + P P QG G P P +P+ Sbjct: 555 QVSYSQAGPNGPPVSSSSNSSSSTSQGSYPCSHPSPSQGPQGAPYPF-----PPVPTVTT 609 Query: 406 QFEYPIHRLENRSMHPYSEPVFSMQHPPP--QQAPNQRLQHFDAPPYMNVAKRPRFDF-- 461 + + P S PPP ++AP+ PP P F Sbjct: 610 SSATLSTVIATVASSPAGYKTASPPGPPPYGKRAPSPGAYKTATPPGYKPGSPPSFRTGT 669 Query: 462 -PGSAGVDRCASWNGSMHNGALDNHLSPSAYPGLPGEFTPPVPDSFPSGPPLQHPAPDHQ 520 PG G A G+ G SP+ PG P P PS PP Sbjct: 670 PPGYRGTSPPAG-PGTFKPG------SPTVGPG---PLPPAGPSGLPSLPPPPAAPASGP 719 Query: 521 SLQQQQQQQQQQQQQQ 536 L Q +Q+ ++ + Sbjct: 720 PLSATQIKQEPAEEYE 735 Score = 73.2 bits (178), Expect = 2e-12 Identities = 163/672 (24%), Positives = 220/672 (32%), Gaps = 137/672 (20%) Query: 154 EHMAESQGPESFGPQRPGNLPDFHSSGASSHAVPAPCLPLDQSPNRA-ASFHGLPSSSGS 212 E+ ++S S GP RP + P P+P P D +P + ASF PS + + Sbjct: 142 ENDSDSSSGLSQGPARPYHPPPLFP--------PSP-QPPDSTPRQPEASFEPHPSVTPT 192 Query: 213 DSHS-LEPRRVTNQGAVDSLEYNYPGEAPSGHFDMFSPSDSEGQLPHYAAGRQVPGGAFP 271 H+ +EP S + P AP H ++ P + G L G + Sbjct: 193 GYHAPMEPPT--------SRMFQAPPGAPPPHPQLY-PGGTGGVLSGPPMGPK------- 236 Query: 272 GASAMPRAAGMVGLSKMHAQPPQQQPQQQQQPQQQQQQHGVFFERFSGARKMPVGLEPSV 331 G A G G K H PP P V SGA P Sbjct: 237 GGGAASSVGGPNG-GKQH--PPPTTPIS------------VSSSGASGAPPTKPPTTPVG 281 Query: 332 GSRHPLMQPPQQAP------PPPQQQPPQQPPQQQPPPPPGLLVRQNSCPPALPRPQ--- 382 G P PP P PPP P +P PPGL + P LP P Sbjct: 282 GGNLPSAPPPANFPHVTPNLPPP---PALRPLNNASASPPGLGAQP--LPGHLPSPHAMG 336 Query: 383 QGEAGTPSGGLQDGGPMLPSQHA-------------QFEYPIHRLENRSMHPYSEPVFSM 429 QG G P G + G + PS H+ +F Y + + S S Sbjct: 337 QGMGGLPPGP-EKGPTLAPSPHSLPPASSSAPAPPMRFPYSSSSSSSAAASSSSSSSSSS 395 Query: 430 QHP-PPQQAPNQRLQHFDAPPYMNVAKRP-RFDFPGSAGVDRCASWNGSMHNGALDNHLS 487 P P QA F P ++V+ +P ++ P + A W+ L Sbjct: 396 ASPFPASQALPSYPHSFPPPTSLSVSNQPPKYTQPS---LPSQAVWSQGPPPPPPYGRLL 452 Query: 488 PSAYPGLPGEFTPPVPDSFPSGPPLQHPAPDHQSLQQQQQQQQQQQQQQQQQQQQQQQQQ 547 ++ PG F P + PP+ HQ QQQQQQQQQQQQQQQQ Sbjct: 453 ANSNAH-PGPFPPSTGAQSTAHPPVSTHHHHHQQQQQQQQQQQQQQQQQQQHHGNSGPPP 511 Query: 548 QQQRQNAALMIKQMASRNQQQRLRQPNLAQL-------GH-PGDVGQGGLVHGGPVGGLA 599 + ++ +S + P+L L H P Q GP G Sbjct: 512 PGAFPHP---LEGGSSHHAHPYAMSPSLGSLRPYPPGPAHLPPPHSQVSYSQAGPNG--- 565 Query: 600 QPNFEREGGSTGAGRLGTFEQQAPHLAQESAWFSGPHPPPGDLLPRRMGGSGLPADCGPH 659 P S+ + G++ P +Q P PP + S + A Sbjct: 566 -PPVSSSSNSSSSTSQGSYPCSHPSPSQGPQGAPYPFPPVPTVTTSSATLSTVIATVASS 624 Query: 660 DPSLAPPPPPGGSGVLFRGPLQEPMRMPGEGHVPALPSPGLQFGGSLGGLGQLQSPGAGV 719 PP GP R P G PG + PG+ Sbjct: 625 PAGYKTASPP--------GPPPYGKRAPSPGAYKTATPPGYK-------------PGS-- 661 Query: 720 GLPSAASERRPPPPDFATSALGGQPGFPFGAAGRQSTPHSGPGVNSP--PSAGGGGGSSG 777 PP F T G PG+ R ++P +GPG P P+ G G Sbjct: 662 ------------PPSFRT---GTPPGY------RGTSPPAGPGTFKPGSPTVGPGPLPPA 700 Query: 778 GGGGGGAYPPQP 789 G G + PP P Sbjct: 701 GPSGLPSLPPPP 712 Score = 64.7 bits (156), Expect = 6e-10 Identities = 132/565 (23%), Positives = 185/565 (32%), Gaps = 84/565 (14%) Query: 635 PHPPPGDLLPRRMGGSGLP----ADCGPHDPSLAP-----------PPP-----PGGSGV 674 P P P D PR+ S P G H P P PPP PGG+G Sbjct: 167 PSPQPPDSTPRQPEASFEPHPSVTPTGYHAPMEPPTSRMFQAPPGAPPPHPQLYPGGTGG 226 Query: 675 LFRGPLQEPMRMPGEGHVPALPSPGLQFGGSLGGLGQLQSPGAGVGLPSAASERRPPPPD 734 + GP PM G G ++ GG GG Q P + + S+ + PP Sbjct: 227 VLSGP---PMGPKGGGAASSV-------GGPNGGK-QHPPPTTPISVSSSGASGAPPTKP 275 Query: 735 FATSALGGQ-PGFPFGAAGRQSTPH---------------SGPGVNSPPSAGGGGGSSGG 778 T GG P P A TP+ S PG+ + P G Sbjct: 276 PTTPVGGGNLPSAPPPANFPHVTPNLPPPPALRPLNNASASPPGLGAQPLPGHLPSPHAM 335 Query: 779 GGGGGAYPPQPDFQPSQRTSASKLGALSLGSFNKP-------SSKDNLFGQSCLAALSTA 831 G G G PP P+ P+ S L S + P SS + S ++ S++ Sbjct: 336 GQGMGGLPPGPEKGPTLAPSPHSLPPASSSAPAPPMRFPYSSSSSSSAAASSSSSSSSSS 395 Query: 832 CQNMIASLGAPNLNVTFNKKNPPEGKRKLSQNETDGAAVAGNPGSDYFPGGTAPGAPGPG 891 AS P+ +F PP +S N+ P + G P P Sbjct: 396 ASPFPASQALPSYPHSF----PPPTSLSVS-NQPPKYTQPSLPSQAVWSQG-----PPPP 445 Query: 892 GPSGTSSSGSKASGPPNPPAQGDGTSLSPNYTLESTSGNDGKPVSGGGGRGRGRRKR--- 948 P G + S A P PP+ G ++ P + + + + ++++ Sbjct: 446 PPYGRLLANSNAHPGPFPPSTGAQSTAHPPVSTHHHHHQQQQQQQQQQQQQQQQQQQHHG 505 Query: 949 DSGHVSPGTFFDKYSAAPDSGGAPGVSPGQQQASGAAVGGSSAGETRGAPTPHEKALTSP 1008 +SG PG F + G + P S ++ G P PH + S Sbjct: 506 NSGPPPPGAF----PHPLEGGSSHHAHPYAMSPSLGSLRPYPPGPAH-LPPPHSQVSYSQ 560 Query: 1009 SWGKGAELLLGDQPDLIGSLDGGAKSDSSSPNVGEFASDEVSTSYANEDEVSSSSDNPQA 1068 + G + S G SP+ G + S++ A Sbjct: 561 AGPNGPPVSSSSNSSSSTS-QGSYPCSHPSPSQGPQGAPYPFPPVPTVTTSSATLSTVIA 619 Query: 1069 LVKASRSPLVTGSPKLPP----RGVGAGEHGPKAPPPALGLGIMSNSTSTPDSYGGGGGP 1124 V +S + T SP PP R G + PP S T TP Y G P Sbjct: 620 TVASSPAGYKTASPPGPPPYGKRAPSPGAYKTATPPGYKPGSPPSFRTGTPPGYRGTSPP 679 Query: 1125 GHPGT--PGLEQVRTPTSSSGAPPP 1147 PGT PG +PT G PP Sbjct: 680 AGPGTFKPG-----SPTVGPGPLPP 699 Score = 62.4 bits (150), Expect = 3e-09 Identities = 91/330 (27%), Positives = 118/330 (35%), Gaps = 60/330 (18%) Query: 874 PGSDYFPGGTA---PGAP-GPGGPSGTSSSGSKASGPPNPPAQGDGTSLSPNYTLESTSG 929 P +PGGT G P GP G SS G G +PP T +S S+SG Sbjct: 215 PHPQLYPGGTGGVLSGPPMGPKGGGAASSVGGPNGGKQHPPPT---TPISV-----SSSG 266 Query: 930 NDGKPVS-------GGGGRGRGRRKRDSGHVSPGTF-------FDKYSAAPDSGGA---P 972 G P + GGG + HV+P + SA+P GA P Sbjct: 267 ASGAPPTKPPTTPVGGGNLPSAPPPANFPHVTPNLPPPPALRPLNNASASPPGLGAQPLP 326 Query: 973 GVSPGQQQASGAAVGGSSAGETRG---APTPHEKALTSPSWGKGAELLLGDQPDLIGSLD 1029 G P A G +GG G +G AP+PH S S + S Sbjct: 327 GHLPSPH-AMGQGMGGLPPGPEKGPTLAPSPHSLPPASSS-APAPPMRFPYSSSSSSSAA 384 Query: 1030 GGAKSDSSSPNVGEFASDEVSTSYANEDEVSSSSDNPQALVKASRSPLVTGSPKLPPRGV 1089 + S SSS + F + + SY + S P + S P P LP + V Sbjct: 385 ASSSSSSSSSSASPFPASQALPSYPH-------SFPPPTSLSVSNQPPKYTQPSLPSQAV 437 Query: 1090 GAGEHGPKAPPPALGLGIMSNSTSTPDSYGGGGGPGHPGTPGLEQVRTPTSSSGAPPPDE 1149 + GP PPP L ++NS + P GP P T S+ PP Sbjct: 438 WS--QGPPPPPPYGRL--LANSNAHP-------GPFPPSTGA--------QSTAHPPVST 478 Query: 1150 IHPLEILQAQIQLQRQQFSISEDQPLGLKG 1179 H Q Q Q Q+QQ + Q G G Sbjct: 479 HHHHHQQQQQQQQQQQQQQQQQQQHHGNSG 508 Score = 39.3 bits (90), Expect = 0.025 Identities = 81/315 (25%), Positives = 101/315 (32%), Gaps = 40/315 (12%) Query: 623 PHLAQESAWFSGPHPPP--GDLLPRRMGGSG-LPADCGPHDPSLAPPP---------PPG 670 P L ++ W GP PPP G LL G P G S A PP Sbjct: 430 PSLPSQAVWSQGPPPPPPYGRLLANSNAHPGPFPPSTGAQ--STAHPPVSTHHHHHQQQQ 487 Query: 671 GSGVLFRGPLQEPMRMPGEGHVP---ALPSPGLQFGGSLGGLGQLQSPGAGVGLPSAASE 727 + Q+ + G P A P P L+ G S SP G P Sbjct: 488 QQQQQQQQQQQQQQQHHGNSGPPPPGAFPHP-LEGGSSHHAHPYAMSPSLGSLRPYPPGP 546 Query: 728 RRPPPPDFATS-ALGGQPGFPFGAAGRQSTPHS-GPGVNSPPSAGGGGGSSGGGGGGGAY 785 PPP S + G G P ++ S+ S G S PS S G G + Sbjct: 547 AHLPPPHSQVSYSQAGPNGPPVSSSSNSSSSTSQGSYPCSHPSP-----SQGPQGAPYPF 601 Query: 786 PPQPDFQPSQRTSASKLGALSLGSFN-KPSSKDNLFGQSCLAALSTACQNMIASLGAPNL 844 PP P S T ++ + ++ K +S A A + P Sbjct: 602 PPVPTVTTSSATLSTVIATVASSPAGYKTASPPGPPPYGKRAPSPGAYKTATPPGYKPGS 661 Query: 845 NVTFNKKNPPEGKRKLSQNETDGAAVAGNPGSDYFPGGTAPGAPGPGGPSGTSSSGSKAS 904 +F PP G R S G G+P PG P GPSG S Sbjct: 662 PPSFRTGTPP-GYRGTSPPAGPGTFKPGSPT-------VGPGPLPPAGPSGLPSL----- 708 Query: 905 GPPNPPAQGDGTSLS 919 PP P A G LS Sbjct: 709 -PPPPAAPASGPPLS 722 Score = 37.4 bits (85), Expect = 0.096 Identities = 70/293 (23%), Positives = 94/293 (32%), Gaps = 53/293 (18%) Query: 888 PGPGGPSGTSSSGSKA---SGPPNP-PAQGDGTSLSPNYTLESTSGNDGKPVSGGGGRGR 943 P P PS S ++ G +P D S SP+ + ND S G +G Sbjct: 97 PRPQSPSDLDSLDGRSLNDDGSSDPRDIDQDNRSTSPSIYSPGSVENDSDS-SSGLSQGP 155 Query: 944 GRRKRDSGHVSPGTFFDKYSAAPDSGGA---------PGVSPGQQQASGAAVGGSSAGET 994 R P F PDS P V+P A Sbjct: 156 ARPYH------PPPLFPPSPQPPDSTPRQPEASFEPHPSVTPTGYHAPMEPPTSRMFQAP 209 Query: 995 RGAPTPHEKALTSPSWGKGAELLLGDQPDLIGSLDGGAKSDSSSPNVGEFASDEVSTSYA 1054 GAP PH + + G +L P +G GGA S PN G+ + Sbjct: 210 PGAPPPHPQLYPGGTGG-----VLSGPP--MGPKGGGAASSVGGPNGGKQHPPPTTPI-- 260 Query: 1055 NEDEVSSSSDNPQALVKASRSPLVTGS--------------PKLPPRGVGAGEHGPKAPP 1100 VSSS + K +P+ G+ P LPP + A P Sbjct: 261 ---SVSSSGASGAPPTKPPTTPVGGGNLPSAPPPANFPHVTPNLPPPPALRPLNNASASP 317 Query: 1101 PALGLGIMSNSTSTPDSYGGGGGPGHPG-------TPGLEQVRTPTSSSGAPP 1146 P LG + +P + G G G PG P + +SS+ APP Sbjct: 318 PGLGAQPLPGHLPSPHAMGQGMGGLPPGPEKGPTLAPSPHSLPPASSSAPAPP 370 Score = 33.5 bits (75), Expect = 1.4 Identities = 41/160 (25%), Positives = 56/160 (35%), Gaps = 22/160 (13%) Query: 1015 ELLLGDQPDLIGSLDGGAKSDSSSPNVGEFASDEVSTSYA--NEDEVSSSSDNPQALVKA 1072 EL P + SLDG + +D S + + D STS + + V + SD+ L + Sbjct: 95 ELPRPQSPSDLDSLDGRSLNDDGSSDPRDIDQDNRSTSPSIYSPGSVENDSDSSSGLSQG 154 Query: 1073 SR-----SPLVTGSPKLP--------------PRGVGAGEHGPKAPPPALGLGIMSNSTS 1113 PL SP+ P P G H P PP + + Sbjct: 155 PARPYHPPPLFPPSPQPPDSTPRQPEASFEPHPSVTPTGYHAPMEPPTSRMFQAPPGAPP 214 Query: 1114 T-PDSYGGGGGPGHPGTPGLEQVRTPTSSSGAPPPDEIHP 1152 P Y GG G G P + SS G P + HP Sbjct: 215 PHPQLYPGGTGGVLSGPPMGPKGGGAASSVGGPNGGKQHP 254 >gi|55750041 atrophin-1 [Homo sapiens] Length = 1190 Score = 89.0 bits (219), Expect = 3e-17 Identities = 150/556 (26%), Positives = 190/556 (34%), Gaps = 95/556 (17%) Query: 57 EPPILGMNMEPYGFHARGHSELHAGG----LQAQPVHGFFGGQQPHHGHP--GSHHPHQH 110 EPP M P G H +L+ GG L P+ GG G P G HP Sbjct: 199 EPPTSRMFQAPPGAPPP-HPQLYPGGTGGVLSGPPMGPKGGGAASSVGGPNGGKQHPPPT 257 Query: 111 HPHF--------------------GGNFGGPDPGASCLH---------GGRLLGYGGAAG 141 P GGN P A+ H R L A+ Sbjct: 258 TPISVSSSGASGAPPTKPPTTPVGGGNLPSAPPPANFPHVTPNLPPPPALRPLNNASASP 317 Query: 142 -GLGSQP-PFAEGYEH-MAESQGPESFGPQR-PGNLPDFHSSGASSHAVPAPCLPLDQSP 197 GLG+QP P H M + G GP++ P P HS +S + PAP + S Sbjct: 318 PGLGAQPLPGHLPSPHAMGQGMGGLPPGPEKGPTLAPSPHSLPPASSSAPAPPMRFPYSS 377 Query: 198 NRAASFHGLPSSSGSDSHSLEPRRVTNQGAVDSLEYNYP-------GEAPSGHFDMFSPS 250 + ++S SSS S S S P + A+ S +++P P + PS Sbjct: 378 SSSSSA-AASSSSSSSSSSASPFPASQ--ALPSYPHSFPPPTSLSVSNQPPKYTQPSLPS 434 Query: 251 D---SEGQLPHYAAGRQV------PGGAFPGASAMPRAAGMVGLSKMHAQPPQQQPQQQQ 301 S+G P GR + PG P A A V H Q QQQ QQQQ Sbjct: 435 QAVWSQGPPPPPPYGRLLANSNAHPGPFPPSTGAQSTAHPPVSTHHHHHQQQQQQQQQQQ 494 Query: 302 QPQQQQQQH---------GVF---FERFSGARKMPVGLEPSVGSRHPLMQPPQQAPPPPQ 349 Q QQQQQQH G F E S P + PS+GS P P PPP Sbjct: 495 QQQQQQQQHHGNSGPPPPGAFPHPLEGGSSHHAHPYAMSPSLGSLRPYPPGPAHLPPPHS 554 Query: 350 QQPPQQPPQQQPPPPPGL----LVRQNSCPPALPRPQQGEAGTPSGGLQDGGPMLPSQHA 405 Q Q PP Q S P + P P QG G P P +P+ Sbjct: 555 QVSYSQAGPNGPPVSSSSNSSSSTSQGSYPCSHPSPSQGPQGAPYPF-----PPVPTVTT 609 Query: 406 QFEYPIHRLENRSMHPYSEPVFSMQHPPP--QQAPNQRLQHFDAPPYMNVAKRPRFDF-- 461 + + P S PPP ++AP+ PP P F Sbjct: 610 SSATLSTVIATVASSPAGYKTASPPGPPPYGKRAPSPGAYKTATPPGYKPGSPPSFRTGT 669 Query: 462 -PGSAGVDRCASWNGSMHNGALDNHLSPSAYPGLPGEFTPPVPDSFPSGPPLQHPAPDHQ 520 PG G A G+ G SP+ PG P P PS PP Sbjct: 670 PPGYRGTSPPAG-PGTFKPG------SPTVGPG---PLPPAGPSGLPSLPPPPAAPASGP 719 Query: 521 SLQQQQQQQQQQQQQQ 536 L Q +Q+ ++ + Sbjct: 720 PLSATQIKQEPAEEYE 735 Score = 73.2 bits (178), Expect = 2e-12 Identities = 163/672 (24%), Positives = 220/672 (32%), Gaps = 137/672 (20%) Query: 154 EHMAESQGPESFGPQRPGNLPDFHSSGASSHAVPAPCLPLDQSPNRA-ASFHGLPSSSGS 212 E+ ++S S GP RP + P P+P P D +P + ASF PS + + Sbjct: 142 ENDSDSSSGLSQGPARPYHPPPLFP--------PSP-QPPDSTPRQPEASFEPHPSVTPT 192 Query: 213 DSHS-LEPRRVTNQGAVDSLEYNYPGEAPSGHFDMFSPSDSEGQLPHYAAGRQVPGGAFP 271 H+ +EP S + P AP H ++ P + G L G + Sbjct: 193 GYHAPMEPPT--------SRMFQAPPGAPPPHPQLY-PGGTGGVLSGPPMGPK------- 236 Query: 272 GASAMPRAAGMVGLSKMHAQPPQQQPQQQQQPQQQQQQHGVFFERFSGARKMPVGLEPSV 331 G A G G K H PP P V SGA P Sbjct: 237 GGGAASSVGGPNG-GKQH--PPPTTPIS------------VSSSGASGAPPTKPPTTPVG 281 Query: 332 GSRHPLMQPPQQAP------PPPQQQPPQQPPQQQPPPPPGLLVRQNSCPPALPRPQ--- 382 G P PP P PPP P +P PPGL + P LP P Sbjct: 282 GGNLPSAPPPANFPHVTPNLPPP---PALRPLNNASASPPGLGAQP--LPGHLPSPHAMG 336 Query: 383 QGEAGTPSGGLQDGGPMLPSQHA-------------QFEYPIHRLENRSMHPYSEPVFSM 429 QG G P G + G + PS H+ +F Y + + S S Sbjct: 337 QGMGGLPPGP-EKGPTLAPSPHSLPPASSSAPAPPMRFPYSSSSSSSAAASSSSSSSSSS 395 Query: 430 QHP-PPQQAPNQRLQHFDAPPYMNVAKRP-RFDFPGSAGVDRCASWNGSMHNGALDNHLS 487 P P QA F P ++V+ +P ++ P + A W+ L Sbjct: 396 ASPFPASQALPSYPHSFPPPTSLSVSNQPPKYTQPS---LPSQAVWSQGPPPPPPYGRLL 452 Query: 488 PSAYPGLPGEFTPPVPDSFPSGPPLQHPAPDHQSLQQQQQQQQQQQQQQQQQQQQQQQQQ 547 ++ PG F P + PP+ HQ QQQQQQQQQQQQQQQQ Sbjct: 453 ANSNAH-PGPFPPSTGAQSTAHPPVSTHHHHHQQQQQQQQQQQQQQQQQQQHHGNSGPPP 511 Query: 548 QQQRQNAALMIKQMASRNQQQRLRQPNLAQL-------GH-PGDVGQGGLVHGGPVGGLA 599 + ++ +S + P+L L H P Q GP G Sbjct: 512 PGAFPHP---LEGGSSHHAHPYAMSPSLGSLRPYPPGPAHLPPPHSQVSYSQAGPNG--- 565 Query: 600 QPNFEREGGSTGAGRLGTFEQQAPHLAQESAWFSGPHPPPGDLLPRRMGGSGLPADCGPH 659 P S+ + G++ P +Q P PP + S + A Sbjct: 566 -PPVSSSSNSSSSTSQGSYPCSHPSPSQGPQGAPYPFPPVPTVTTSSATLSTVIATVASS 624 Query: 660 DPSLAPPPPPGGSGVLFRGPLQEPMRMPGEGHVPALPSPGLQFGGSLGGLGQLQSPGAGV 719 PP GP R P G PG + PG+ Sbjct: 625 PAGYKTASPP--------GPPPYGKRAPSPGAYKTATPPGYK-------------PGS-- 661 Query: 720 GLPSAASERRPPPPDFATSALGGQPGFPFGAAGRQSTPHSGPGVNSP--PSAGGGGGSSG 777 PP F T G PG+ R ++P +GPG P P+ G G Sbjct: 662 ------------PPSFRT---GTPPGY------RGTSPPAGPGTFKPGSPTVGPGPLPPA 700 Query: 778 GGGGGGAYPPQP 789 G G + PP P Sbjct: 701 GPSGLPSLPPPP 712 Score = 64.7 bits (156), Expect = 6e-10 Identities = 132/565 (23%), Positives = 185/565 (32%), Gaps = 84/565 (14%) Query: 635 PHPPPGDLLPRRMGGSGLP----ADCGPHDPSLAP-----------PPP-----PGGSGV 674 P P P D PR+ S P G H P P PPP PGG+G Sbjct: 167 PSPQPPDSTPRQPEASFEPHPSVTPTGYHAPMEPPTSRMFQAPPGAPPPHPQLYPGGTGG 226 Query: 675 LFRGPLQEPMRMPGEGHVPALPSPGLQFGGSLGGLGQLQSPGAGVGLPSAASERRPPPPD 734 + GP PM G G ++ GG GG Q P + + S+ + PP Sbjct: 227 VLSGP---PMGPKGGGAASSV-------GGPNGGK-QHPPPTTPISVSSSGASGAPPTKP 275 Query: 735 FATSALGGQ-PGFPFGAAGRQSTPH---------------SGPGVNSPPSAGGGGGSSGG 778 T GG P P A TP+ S PG+ + P G Sbjct: 276 PTTPVGGGNLPSAPPPANFPHVTPNLPPPPALRPLNNASASPPGLGAQPLPGHLPSPHAM 335 Query: 779 GGGGGAYPPQPDFQPSQRTSASKLGALSLGSFNKP-------SSKDNLFGQSCLAALSTA 831 G G G PP P+ P+ S L S + P SS + S ++ S++ Sbjct: 336 GQGMGGLPPGPEKGPTLAPSPHSLPPASSSAPAPPMRFPYSSSSSSSAAASSSSSSSSSS 395 Query: 832 CQNMIASLGAPNLNVTFNKKNPPEGKRKLSQNETDGAAVAGNPGSDYFPGGTAPGAPGPG 891 AS P+ +F PP +S N+ P + G P P Sbjct: 396 ASPFPASQALPSYPHSF----PPPTSLSVS-NQPPKYTQPSLPSQAVWSQG-----PPPP 445 Query: 892 GPSGTSSSGSKASGPPNPPAQGDGTSLSPNYTLESTSGNDGKPVSGGGGRGRGRRKR--- 948 P G + S A P PP+ G ++ P + + + + ++++ Sbjct: 446 PPYGRLLANSNAHPGPFPPSTGAQSTAHPPVSTHHHHHQQQQQQQQQQQQQQQQQQQHHG 505 Query: 949 DSGHVSPGTFFDKYSAAPDSGGAPGVSPGQQQASGAAVGGSSAGETRGAPTPHEKALTSP 1008 +SG PG F + G + P S ++ G P PH + S Sbjct: 506 NSGPPPPGAF----PHPLEGGSSHHAHPYAMSPSLGSLRPYPPGPAH-LPPPHSQVSYSQ 560 Query: 1009 SWGKGAELLLGDQPDLIGSLDGGAKSDSSSPNVGEFASDEVSTSYANEDEVSSSSDNPQA 1068 + G + S G SP+ G + S++ A Sbjct: 561 AGPNGPPVSSSSNSSSSTS-QGSYPCSHPSPSQGPQGAPYPFPPVPTVTTSSATLSTVIA 619 Query: 1069 LVKASRSPLVTGSPKLPP----RGVGAGEHGPKAPPPALGLGIMSNSTSTPDSYGGGGGP 1124 V +S + T SP PP R G + PP S T TP Y G P Sbjct: 620 TVASSPAGYKTASPPGPPPYGKRAPSPGAYKTATPPGYKPGSPPSFRTGTPPGYRGTSPP 679 Query: 1125 GHPGT--PGLEQVRTPTSSSGAPPP 1147 PGT PG +PT G PP Sbjct: 680 AGPGTFKPG-----SPTVGPGPLPP 699 Score = 62.4 bits (150), Expect = 3e-09 Identities = 91/330 (27%), Positives = 118/330 (35%), Gaps = 60/330 (18%) Query: 874 PGSDYFPGGTA---PGAP-GPGGPSGTSSSGSKASGPPNPPAQGDGTSLSPNYTLESTSG 929 P +PGGT G P GP G SS G G +PP T +S S+SG Sbjct: 215 PHPQLYPGGTGGVLSGPPMGPKGGGAASSVGGPNGGKQHPPPT---TPISV-----SSSG 266 Query: 930 NDGKPVS-------GGGGRGRGRRKRDSGHVSPGTF-------FDKYSAAPDSGGA---P 972 G P + GGG + HV+P + SA+P GA P Sbjct: 267 ASGAPPTKPPTTPVGGGNLPSAPPPANFPHVTPNLPPPPALRPLNNASASPPGLGAQPLP 326 Query: 973 GVSPGQQQASGAAVGGSSAGETRG---APTPHEKALTSPSWGKGAELLLGDQPDLIGSLD 1029 G P A G +GG G +G AP+PH S S + S Sbjct: 327 GHLPSPH-AMGQGMGGLPPGPEKGPTLAPSPHSLPPASSS-APAPPMRFPYSSSSSSSAA 384 Query: 1030 GGAKSDSSSPNVGEFASDEVSTSYANEDEVSSSSDNPQALVKASRSPLVTGSPKLPPRGV 1089 + S SSS + F + + SY + S P + S P P LP + V Sbjct: 385 ASSSSSSSSSSASPFPASQALPSYPH-------SFPPPTSLSVSNQPPKYTQPSLPSQAV 437 Query: 1090 GAGEHGPKAPPPALGLGIMSNSTSTPDSYGGGGGPGHPGTPGLEQVRTPTSSSGAPPPDE 1149 + GP PPP L ++NS + P GP P T S+ PP Sbjct: 438 WS--QGPPPPPPYGRL--LANSNAHP-------GPFPPSTGA--------QSTAHPPVST 478 Query: 1150 IHPLEILQAQIQLQRQQFSISEDQPLGLKG 1179 H Q Q Q Q+QQ + Q G G Sbjct: 479 HHHHHQQQQQQQQQQQQQQQQQQQHHGNSG 508 Score = 39.3 bits (90), Expect = 0.025 Identities = 81/315 (25%), Positives = 101/315 (32%), Gaps = 40/315 (12%) Query: 623 PHLAQESAWFSGPHPPP--GDLLPRRMGGSG-LPADCGPHDPSLAPPP---------PPG 670 P L ++ W GP PPP G LL G P G S A PP Sbjct: 430 PSLPSQAVWSQGPPPPPPYGRLLANSNAHPGPFPPSTGAQ--STAHPPVSTHHHHHQQQQ 487 Query: 671 GSGVLFRGPLQEPMRMPGEGHVP---ALPSPGLQFGGSLGGLGQLQSPGAGVGLPSAASE 727 + Q+ + G P A P P L+ G S SP G P Sbjct: 488 QQQQQQQQQQQQQQQHHGNSGPPPPGAFPHP-LEGGSSHHAHPYAMSPSLGSLRPYPPGP 546 Query: 728 RRPPPPDFATS-ALGGQPGFPFGAAGRQSTPHS-GPGVNSPPSAGGGGGSSGGGGGGGAY 785 PPP S + G G P ++ S+ S G S PS S G G + Sbjct: 547 AHLPPPHSQVSYSQAGPNGPPVSSSSNSSSSTSQGSYPCSHPSP-----SQGPQGAPYPF 601 Query: 786 PPQPDFQPSQRTSASKLGALSLGSFN-KPSSKDNLFGQSCLAALSTACQNMIASLGAPNL 844 PP P S T ++ + ++ K +S A A + P Sbjct: 602 PPVPTVTTSSATLSTVIATVASSPAGYKTASPPGPPPYGKRAPSPGAYKTATPPGYKPGS 661 Query: 845 NVTFNKKNPPEGKRKLSQNETDGAAVAGNPGSDYFPGGTAPGAPGPGGPSGTSSSGSKAS 904 +F PP G R S G G+P PG P GPSG S Sbjct: 662 PPSFRTGTPP-GYRGTSPPAGPGTFKPGSPT-------VGPGPLPPAGPSGLPSL----- 708 Query: 905 GPPNPPAQGDGTSLS 919 PP P A G LS Sbjct: 709 -PPPPAAPASGPPLS 722 Score = 37.4 bits (85), Expect = 0.096 Identities = 70/293 (23%), Positives = 94/293 (32%), Gaps = 53/293 (18%) Query: 888 PGPGGPSGTSSSGSKA---SGPPNP-PAQGDGTSLSPNYTLESTSGNDGKPVSGGGGRGR 943 P P PS S ++ G +P D S SP+ + ND S G +G Sbjct: 97 PRPQSPSDLDSLDGRSLNDDGSSDPRDIDQDNRSTSPSIYSPGSVENDSDS-SSGLSQGP 155 Query: 944 GRRKRDSGHVSPGTFFDKYSAAPDSGGA---------PGVSPGQQQASGAAVGGSSAGET 994 R P F PDS P V+P A Sbjct: 156 ARPYH------PPPLFPPSPQPPDSTPRQPEASFEPHPSVTPTGYHAPMEPPTSRMFQAP 209 Query: 995 RGAPTPHEKALTSPSWGKGAELLLGDQPDLIGSLDGGAKSDSSSPNVGEFASDEVSTSYA 1054 GAP PH + + G +L P +G GGA S PN G+ + Sbjct: 210 PGAPPPHPQLYPGGTGG-----VLSGPP--MGPKGGGAASSVGGPNGGKQHPPPTTPI-- 260 Query: 1055 NEDEVSSSSDNPQALVKASRSPLVTGS--------------PKLPPRGVGAGEHGPKAPP 1100 VSSS + K +P+ G+ P LPP + A P Sbjct: 261 ---SVSSSGASGAPPTKPPTTPVGGGNLPSAPPPANFPHVTPNLPPPPALRPLNNASASP 317 Query: 1101 PALGLGIMSNSTSTPDSYGGGGGPGHPG-------TPGLEQVRTPTSSSGAPP 1146 P LG + +P + G G G PG P + +SS+ APP Sbjct: 318 PGLGAQPLPGHLPSPHAMGQGMGGLPPGPEKGPTLAPSPHSLPPASSSAPAPP 370 Score = 33.5 bits (75), Expect = 1.4 Identities = 41/160 (25%), Positives = 56/160 (35%), Gaps = 22/160 (13%) Query: 1015 ELLLGDQPDLIGSLDGGAKSDSSSPNVGEFASDEVSTSYA--NEDEVSSSSDNPQALVKA 1072 EL P + SLDG + +D S + + D STS + + V + SD+ L + Sbjct: 95 ELPRPQSPSDLDSLDGRSLNDDGSSDPRDIDQDNRSTSPSIYSPGSVENDSDSSSGLSQG 154 Query: 1073 SR-----SPLVTGSPKLP--------------PRGVGAGEHGPKAPPPALGLGIMSNSTS 1113 PL SP+ P P G H P PP + + Sbjct: 155 PARPYHPPPLFPPSPQPPDSTPRQPEASFEPHPSVTPTGYHAPMEPPTSRMFQAPPGAPP 214 Query: 1114 T-PDSYGGGGGPGHPGTPGLEQVRTPTSSSGAPPPDEIHP 1152 P Y GG G G P + SS G P + HP Sbjct: 215 PHPQLYPGGTGGVLSGPPMGPKGGGAASSVGGPNGGKQHP 254 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.310 0.132 0.407 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 77,989,673 Number of Sequences: 37866 Number of extensions: 5722684 Number of successful extensions: 108916 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 1023 Number of HSP's successfully gapped in prelim test: 1813 Number of HSP's that attempted gapping in prelim test: 34220 Number of HSP's gapped (non-prelim): 34931 length of query: 1320 length of database: 18,247,518 effective HSP length: 114 effective length of query: 1206 effective length of database: 13,930,794 effective search space: 16800537564 effective search space used: 16800537564 T: 11 A: 40 X1: 16 ( 7.2 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 42 (21.7 bits) S2: 68 (30.8 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.