Search of human proteins with 55749932

Search of human proteins with 55749932

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|55749932 desmin [Homo sapiens]
         (470 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|55749932 desmin [Homo sapiens]                                     901   0.0  
gi|62414289 vimentin [Homo sapiens]                                   551   e-157
gi|21264345 peripherin [Homo sapiens]                                 514   e-146
gi|4503979 glial fibrillary acidic protein isoform 1 [Homo sapiens]   479   e-135
gi|196115290 glial fibrillary acidic protein isoform 2 [Homo sap...   444   e-124
gi|14249342 internexin neuronal intermediate filament protein, a...   369   e-102
gi|105990539 neurofilament, light polypeptide 68kDa [Homo sapiens]    348   5e-96
gi|157738649 neurofilament, medium polypeptide 150kDa isoform 1 ...   322   6e-88
gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens]    283   2e-76
gi|4504919 keratin 8 [Homo sapiens]                                   258   6e-69
gi|153791158 keratin 75 [Homo sapiens]                                237   1e-62
gi|67782365 keratin 7 [Homo sapiens]                                  235   7e-62
gi|119395754 keratin 5 [Homo sapiens]                                 231   1e-60
gi|155969697 keratin 6C [Homo sapiens]                                229   5e-60
gi|15431316 keratin, hair, basic, 4 [Homo sapiens]                    227   2e-59
gi|119703753 keratin 6B [Homo sapiens]                                227   2e-59
gi|109255249 keratin 4 [Homo sapiens]                                 224   1e-58
gi|109148552 keratin 3 [Homo sapiens]                                 224   1e-58
gi|5031839 keratin 6A [Homo sapiens]                                  224   2e-58
gi|153791670 keratin 76 [Homo sapiens]                                222   5e-58
gi|119395750 keratin 1 [Homo sapiens]                                 221   1e-57
gi|32567786 keratin 6L [Homo sapiens]                                 219   5e-57
gi|239755818 PREDICTED: hypothetical protein isoform 2 [Homo sap...   218   7e-57
gi|239755816 PREDICTED: hypothetical protein isoform 1 [Homo sap...   218   7e-57
gi|239755814 PREDICTED: hypothetical protein isoform 3 [Homo sap...   218   7e-57
gi|14318422 keratin 86 [Homo sapiens]                                 218   7e-57
gi|169790841 keratin 83 [Homo sapiens]                                218   9e-57
gi|148612803 keratin 6 irs4 [Homo sapiens]                            217   2e-56
gi|27477127 keratin 82 [Homo sapiens]                                 216   3e-56
gi|169790853 keratin, hair, basic, 1 [Homo sapiens]                   215   6e-56

>gi|55749932 desmin [Homo sapiens]
          Length = 470

 Score =  901 bits (2329), Expect = 0.0
 Identities = 470/470 (100%), Positives = 470/470 (100%)

Query: 1   MSQAYSSSQRVSSYRRTFGGAPGFPLGSPLSSPVFPRAGFGSKGSSSSVTSRVYQVSRTS 60
           MSQAYSSSQRVSSYRRTFGGAPGFPLGSPLSSPVFPRAGFGSKGSSSSVTSRVYQVSRTS
Sbjct: 1   MSQAYSSSQRVSSYRRTFGGAPGFPLGSPLSSPVFPRAGFGSKGSSSSVTSRVYQVSRTS 60

Query: 61  GGAGGLGSLRASRLGTTRTPSSYGAGELLDFSLADAVNQEFLTTRTNEKVELQELNDRFA 120
           GGAGGLGSLRASRLGTTRTPSSYGAGELLDFSLADAVNQEFLTTRTNEKVELQELNDRFA
Sbjct: 61  GGAGGLGSLRASRLGTTRTPSSYGAGELLDFSLADAVNQEFLTTRTNEKVELQELNDRFA 120

Query: 121 NYIEKVRFLEQQNAALAAEVNRLKGREPTRVAELYEEELRELRRQVEVLTNQRARVDVER 180
           NYIEKVRFLEQQNAALAAEVNRLKGREPTRVAELYEEELRELRRQVEVLTNQRARVDVER
Sbjct: 121 NYIEKVRFLEQQNAALAAEVNRLKGREPTRVAELYEEELRELRRQVEVLTNQRARVDVER 180

Query: 181 DNLLDDLQRLKAKLQEEIQLKEEAENNLAAFRADVDAATLARIDLERRIESLNEEIAFLK 240
           DNLLDDLQRLKAKLQEEIQLKEEAENNLAAFRADVDAATLARIDLERRIESLNEEIAFLK
Sbjct: 181 DNLLDDLQRLKAKLQEEIQLKEEAENNLAAFRADVDAATLARIDLERRIESLNEEIAFLK 240

Query: 241 KVHEEEIRELQAQLQEQQVQVEMDMSKPDLTAALRDIRAQYETIAAKNISEAEEWYKSKV 300
           KVHEEEIRELQAQLQEQQVQVEMDMSKPDLTAALRDIRAQYETIAAKNISEAEEWYKSKV
Sbjct: 241 KVHEEEIRELQAQLQEQQVQVEMDMSKPDLTAALRDIRAQYETIAAKNISEAEEWYKSKV 300

Query: 301 SDLTQAANKNNDALRQAKQEMMEYRHQIQSYTCEIDALKGTNDSLMRQMRELEDRFASEA 360
           SDLTQAANKNNDALRQAKQEMMEYRHQIQSYTCEIDALKGTNDSLMRQMRELEDRFASEA
Sbjct: 301 SDLTQAANKNNDALRQAKQEMMEYRHQIQSYTCEIDALKGTNDSLMRQMRELEDRFASEA 360

Query: 361 SGYQDNIARLEEEIRHLKDEMARHLREYQDLLNVKMALDVEIATYRKLLEGEESRINLPI 420
           SGYQDNIARLEEEIRHLKDEMARHLREYQDLLNVKMALDVEIATYRKLLEGEESRINLPI
Sbjct: 361 SGYQDNIARLEEEIRHLKDEMARHLREYQDLLNVKMALDVEIATYRKLLEGEESRINLPI 420

Query: 421 QTYSALNFRETSPEQRGSEVHTKKTVMIKTIETRDGEVVSEATQQQHEVL 470
           QTYSALNFRETSPEQRGSEVHTKKTVMIKTIETRDGEVVSEATQQQHEVL
Sbjct: 421 QTYSALNFRETSPEQRGSEVHTKKTVMIKTIETRDGEVVSEATQQQHEVL 470


>gi|62414289 vimentin [Homo sapiens]
          Length = 466

 Score =  551 bits (1420), Expect = e-157
 Identities = 291/464 (62%), Positives = 365/464 (78%), Gaps = 12/464 (2%)

Query: 12  SSYRRTFGGAPGFPLGSPLSSPVFPRAGFGSKGSSSSVTSRVYQVSRTSGGAGGLGSLRA 71
           SSYRR FGG PG       S P   R+   +   + S+ S +   +  S  A   G + A
Sbjct: 9   SSYRRMFGG-PG-----TASRPSSSRSYVTTSTRTYSLGSALRPSTSRSLYASSPGGVYA 62

Query: 72  SRLGTTRTPSSYGAGELL----DFSLADAVNQEFLTTRTNEKVELQELNDRFANYIEKVR 127
           +R    R  SS     LL    DFSLADA+N EF  TRTNEKVELQELNDRFANYI+KVR
Sbjct: 63  TRSSAVRLRSSVPGVRLLQDSVDFSLADAINTEFKNTRTNEKVELQELNDRFANYIDKVR 122

Query: 128 FLEQQNAALAAEVNRLKGREPTRVAELYEEELRELRRQVEVLTNQRARVDVERDNLLDDL 187
           FLEQQN  L AE+ +LKG+  +R+ +LYEEE+RELRRQV+ LTN +ARV+VERDNL +D+
Sbjct: 123 FLEQQNKILLAELEQLKGQGKSRLGDLYEEEMRELRRQVDQLTNDKARVEVERDNLAEDI 182

Query: 188 QRLKAKLQEEIQLKEEAENNLAAFRADVDAATLARIDLERRIESLNEEIAFLKKVHEEEI 247
            RL+ KLQEE+  +EEAEN L +FR DVD A+LAR+DLER++ESL EEIAFLKK+HEEEI
Sbjct: 183 MRLREKLQEEMLQREEAENTLQSFRQDVDNASLARLDLERKVESLQEEIAFLKKLHEEEI 242

Query: 248 RELQAQLQEQQVQVEMDMSKPDLTAALRDIRAQYETIAAKNISEAEEWYKSKVSDLTQAA 307
           +ELQAQ+QEQ VQ+++D+SKPDLTAALRD+R QYE++AAKN+ EAEEWYKSK +DL++AA
Sbjct: 243 QELQAQIQEQHVQIDVDVSKPDLTAALRDVRQQYESVAAKNLQEAEEWYKSKFADLSEAA 302

Query: 308 NKNNDALRQAKQEMMEYRHQIQSYTCEIDALKGTNDSLMRQMRELEDRFASEASGYQDNI 367
           N+NNDALRQAKQE  EYR Q+QS TCE+DALKGTN+SL RQMRE+E+ FA EA+ YQD I
Sbjct: 303 NRNNDALRQAKQESTEYRRQVQSLTCEVDALKGTNESLERQMREMEENFAVEAANYQDTI 362

Query: 368 ARLEEEIRHLKDEMARHLREYQDLLNVKMALDVEIATYRKLLEGEESRINLPIQTYSALN 427
            RL++EI+++K+EMARHLREYQDLLNVKMALD+EIATYRKLLEGEESRI+LP+  +S+LN
Sbjct: 363 GRLQDEIQNMKEEMARHLREYQDLLNVKMALDIEIATYRKLLEGEESRISLPLPNFSSLN 422

Query: 428 FRETSPEQRG-SEVHTKKTVMIKTIETRDGEVVSEATQQQHEVL 470
            RET+ +     + H+K+T++IKT+ETRDG+V++E T Q H+ L
Sbjct: 423 LRETNLDSLPLVDTHSKRTLLIKTVETRDGQVINE-TSQHHDDL 465


>gi|21264345 peripherin [Homo sapiens]
          Length = 470

 Score =  514 bits (1323), Expect = e-146
 Identities = 277/469 (59%), Positives = 360/469 (76%), Gaps = 31/469 (6%)

Query: 12  SSYRRTFGGAPGFPLGSPLSSPVFPRAGFGSKGSSSSVTSRVYQVSRTSGGAGGLGSLRA 71
           +SYRRTFG  P                   S G+ S  +S  +  SR  G A    S+R 
Sbjct: 15  TSYRRTFGPPPSL-----------------SPGAFSYSSSSRFSSSRLLGSASPSSSVR- 56

Query: 72  SRLGTTRTPSSYGAGELL-------DFSLADAVNQEFLTTRTNEKVELQELNDRFANYIE 124
             LG+ R+P + GAG LL       DFS+A+A+NQEFL TR+NEK ELQELNDRFAN+IE
Sbjct: 57  --LGSFRSPRA-GAGALLRLPSERLDFSMAEALNQEFLATRSNEKQELQELNDRFANFIE 113

Query: 125 KVRFLEQQNAALAAEVNRLKGREPTRVAELYEEELRELRRQVEVLTNQRARVDVERDNLL 184
           KVRFLEQQNAAL  E+++ +G+EP R  +L ++ELRELRR++E+L  +R RV VERD L 
Sbjct: 114 KVRFLEQQNAALRGELSQARGQEPARADQLCQQELRELRRELELLGRERDRVQVERDGLA 173

Query: 185 DDLQRLKAKLQEEIQLKEEAENNLAAFRADVDAATLARIDLERRIESLNEEIAFLKKVHE 244
           +DL  LK +L+EE + +E+AE+NL  FR DVD ATL+R++LER+IESL +EI FLKK+HE
Sbjct: 174 EDLAALKQRLEEETRKREDAEHNLVLFRKDVDDATLSRLELERKIESLMDEIEFLKKLHE 233

Query: 245 EEIRELQAQLQEQQVQ-VEMDMS-KPDLTAALRDIRAQYETIAAKNISEAEEWYKSKVSD 302
           EE+R+LQ  ++ QQVQ VE++ + KP+LTAALRDIRAQYE+IAAKN+ EAEEWYKSK +D
Sbjct: 234 EELRDLQVSVESQQVQQVEVEATVKPELTAALRDIRAQYESIAAKNLQEAEEWYKSKYAD 293

Query: 303 LTQAANKNNDALRQAKQEMMEYRHQIQSYTCEIDALKGTNDSLMRQMRELEDRFASEASG 362
           L+ AAN+N++ALRQAKQEM E R QIQS TCE+D L+GTN++L+RQ+RELE++FA EA G
Sbjct: 294 LSDAANRNHEALRQAKQEMNESRRQIQSLTCEVDGLRGTNEALLRQLRELEEQFALEAGG 353

Query: 363 YQDNIARLEEEIRHLKDEMARHLREYQDLLNVKMALDVEIATYRKLLEGEESRINLPIQT 422
           YQ   ARLEEE+R LK+EMARHLREYQ+LLNVKMALD+EIATYRKLLEGEESRI++P+ +
Sbjct: 354 YQAGAARLEEELRQLKEEMARHLREYQELLNVKMALDIEIATYRKLLEGEESRISVPVHS 413

Query: 423 YSALNFRETSPE-QRGSEVHTKKTVMIKTIETRDGEVVSEATQQQHEVL 470
           +++LN + T PE +   + H++KTV+IKTIETR+GEVV+E+ ++Q   L
Sbjct: 414 FASLNIKTTVPEVEPPQDSHSRKTVLIKTIETRNGEVVTESQKEQRSEL 462


>gi|4503979 glial fibrillary acidic protein isoform 1 [Homo sapiens]
          Length = 432

 Score =  479 bits (1232), Expect = e-135
 Identities = 249/429 (58%), Positives = 326/429 (75%), Gaps = 8/429 (1%)

Query: 47  SSVTSRVYQVSRTSGGAGGLGSLR----ASRLGTTRTPSSYGAGELLDFSLADAVNQEFL 102
           +S   R Y VS      GGL   R     +RL   R P        +DFSLA A+N  F 
Sbjct: 7   TSAARRSY-VSSGEMMVGGLAPGRRLGPGTRLSLARMPPPLPTR--VDFSLAGALNAGFK 63

Query: 103 TTRTNEKVELQELNDRFANYIEKVRFLEQQNAALAAEVNRLKGREPTRVAELYEEELREL 162
            TR +E+ E+ ELNDRFA+YIEKVRFLEQQN ALAAE+N+L+ +EPT++A++Y+ ELREL
Sbjct: 64  ETRASERAEMMELNDRFASYIEKVRFLEQQNKALAAELNQLRAKEPTKLADVYQAELREL 123

Query: 163 RRQVEVLTNQRARVDVERDNLLDDLQRLKAKLQEEIQLKEEAENNLAAFRADVDAATLAR 222
           R +++ LT   AR++VERDNL  DL  ++ KLQ+E  L+ EAENNLAA+R + D ATLAR
Sbjct: 124 RLRLDQLTANSARLEVERDNLAQDLATVRQKLQDETNLRLEAENNLAAYRQEADEATLAR 183

Query: 223 IDLERRIESLNEEIAFLKKVHEEEIRELQAQLQEQQVQVEMDMSKPDLTAALRDIRAQYE 282
           +DLER+IESL EEI FL+K+HEEE+RELQ QL  QQV VE+D++KPDLTAAL++IR QYE
Sbjct: 184 LDLERKIESLEEEIRFLRKIHEEEVRELQEQLARQQVHVELDVAKPDLTAALKEIRTQYE 243

Query: 283 TIAAKNISEAEEWYKSKVSDLTQAANKNNDALRQAKQEMMEYRHQIQSYTCEIDALKGTN 342
            +A+ N+ EAEEWY+SK +DLT AA +N + LRQAK E  +YR Q+QS TC++++L+GTN
Sbjct: 244 AMASSNMHEAEEWYRSKFADLTDAAARNAELLRQAKHEANDYRRQLQSLTCDLESLRGTN 303

Query: 343 DSLMRQMRELEDRFASEASGYQDNIARLEEEIRHLKDEMARHLREYQDLLNVKMALDVEI 402
           +SL RQMRE E+R   EA+ YQ+ +ARLEEE + LKDEMARHL+EYQDLLNVK+ALD+EI
Sbjct: 304 ESLERQMREQEERHVREAASYQEALARLEEEGQSLKDEMARHLQEYQDLLNVKLALDIEI 363

Query: 403 ATYRKLLEGEESRINLPIQTYSALNFRETSPEQRG-SEVHTKKTVMIKTIETRDGEVVSE 461
           ATYRKLLEGEE+RI +P+QT+S L  RETS + +  SE H K+ +++KT+E RDGEV+ E
Sbjct: 364 ATYRKLLEGEENRITIPVQTFSNLQIRETSLDTKSVSEGHLKRNIVVKTVEMRDGEVIKE 423

Query: 462 ATQQQHEVL 470
           + Q+  +V+
Sbjct: 424 SKQEHKDVM 432


>gi|196115290 glial fibrillary acidic protein isoform 2 [Homo
           sapiens]
          Length = 431

 Score =  444 bits (1141), Expect = e-124
 Identities = 236/421 (56%), Positives = 309/421 (73%), Gaps = 10/421 (2%)

Query: 47  SSVTSRVYQVSRTSGGAGGLGSLR----ASRLGTTRTPSSYGAGELLDFSLADAVNQEFL 102
           +S   R Y VS      GGL   R     +RL   R P        +DFSLA A+N  F 
Sbjct: 7   TSAARRSY-VSSGEMMVGGLAPGRRLGPGTRLSLARMPPPLPTR--VDFSLAGALNAGFK 63

Query: 103 TTRTNEKVELQELNDRFANYIEKVRFLEQQNAALAAEVNRLKGREPTRVAELYEEELREL 162
            TR +E+ E+ ELNDRFA+YIEKVRFLEQQN ALAAE+N+L+ +EPT++A++Y+ ELREL
Sbjct: 64  ETRASERAEMMELNDRFASYIEKVRFLEQQNKALAAELNQLRAKEPTKLADVYQAELREL 123

Query: 163 RRQVEVLTNQRARVDVERDNLLDDLQRLKAKLQEEIQLKEEAENNLAAFRADVDAATLAR 222
           R +++ LT   AR++VERDNL  DL  ++ KLQ+E  L+ EAENNLAA+R + D ATLAR
Sbjct: 124 RLRLDQLTANSARLEVERDNLAQDLATVRQKLQDETNLRLEAENNLAAYRQEADEATLAR 183

Query: 223 IDLERRIESLNEEIAFLKKVHEEEIRELQAQLQEQQVQVEMDMSKPDLTAALRDIRAQYE 282
           +DLER+IESL EEI FL+K+HEEE+RELQ QL  QQV VE+D++KPDLTAAL++IR QYE
Sbjct: 184 LDLERKIESLEEEIRFLRKIHEEEVRELQEQLARQQVHVELDVAKPDLTAALKEIRTQYE 243

Query: 283 TIAAKNISEAEEWYKSKVSDLTQAANKNNDALRQAKQEMMEYRHQIQSYTCEIDALKGTN 342
            +A+ N+ EAEEWY+SK +DLT AA +N + LRQAK E  +YR Q+QS TC++++L+GTN
Sbjct: 244 AMASSNMHEAEEWYRSKFADLTDAAARNAELLRQAKHEANDYRRQLQSLTCDLESLRGTN 303

Query: 343 DSLMRQMRELEDRFASEASGYQDNIARLEEEIRHLKDEMARHLREYQDLLNVKMALDVEI 402
           +SL RQMRE E+R   EA+ YQ+ +ARLEEE + LKDEMARHL+EYQDLLNVK+ALD+EI
Sbjct: 304 ESLERQMREQEERHVREAASYQEALARLEEEGQSLKDEMARHLQEYQDLLNVKLALDIEI 363

Query: 403 ATYRKLLEGEESRINLPIQTYSALNFR---ETSPEQRGSEVHTKKTVMIKTIETRDGEVV 459
           ATYRKLLEGEE+RI +P+QT+S L  R    T   +        K++ I+ I  +  ++V
Sbjct: 364 ATYRKLLEGEENRITIPVQTFSNLQIRGGKSTKDGENHKVTRYLKSLTIRVIPIQAHQIV 423

Query: 460 S 460
           +
Sbjct: 424 N 424


>gi|14249342 internexin neuronal intermediate filament protein,
           alpha [Homo sapiens]
          Length = 499

 Score =  369 bits (948), Expect = e-102
 Identities = 210/422 (49%), Positives = 292/422 (69%), Gaps = 22/422 (5%)

Query: 12  SSYRRTFGGAPGFPLGSPLSSPVFPRAGFGSKGSSSSVTSRVYQVSRTSGGAG-GLGSLR 70
           SSYR+ FG       GS LS+ +    G G   S S   S V   +  S  +  GLG   
Sbjct: 13  SSYRKVFGD------GSRLSARLSGAGGAGGFRSQSLSRSNVASSAACSSASSLGLG--- 63

Query: 71  ASRLGTTRTPSSYGAGELLDFSLADAVNQEFLTTRTNEKVELQELNDRFANYIEKVRFLE 130
              L   R P+S G    LD S A A   E+   RTNEK +LQ LNDRFA +IEKV  LE
Sbjct: 64  ---LAYRRPPASDG----LDLSQAAARTNEYKIIRTNEKEQLQGLNDRFAVFIEKVHQLE 116

Query: 131 QQNAALAAEVNRLKGR--EPTRVAELYEEELRELRRQVEVLTNQRARVDVERDNLLDDLQ 188
            QN AL AE+  L+ R  EP+RV EL++ ELR+LR Q+E  ++ R++  +ERD L +++Q
Sbjct: 117 TQNRALEAELAALRQRHAEPSRVGELFQRELRDLRAQLEEASSARSQALLERDGLAEEVQ 176

Query: 189 RLKAKLQEEIQLKEEAENNLAAFRADVDAATLARIDLERRIESLNEEIAFLKKVHEEEIR 248
           RL+A+ +EE + +E AE  L A + DVD ATLAR+DLE+++ESL +E+AF+++VH+EE+ 
Sbjct: 177 RLRARCEEESRGREGAERALKAQQRDVDGATLARLDLEKKVESLLDELAFVRQVHDEEVA 236

Query: 249 ELQAQLQ---EQQVQVEMDMSKPDLTAALRDIRAQYETIAAKNISEAEEWYKSKVSDLTQ 305
           EL A LQ   +   +V++ ++KPDLT+ALR+IRAQYE++AAKN+  AEEWYKSK ++L +
Sbjct: 237 ELLATLQASSQAAAEVDVTVAKPDLTSALREIRAQYESLAAKNLQSAEEWYKSKFANLNE 296

Query: 306 AANKNNDALRQAKQEMMEYRHQIQSYTCEIDALKGTNDSLMRQMRELEDRFASEASGYQD 365
            A ++ +A+R +++E+ EYR Q+Q+ T EI+ L+G N+SL RQ+ ELE+R ++E +GYQD
Sbjct: 297 QAARSTEAIRASREEIHEYRRQLQARTIEIEGLRGANESLERQILELEERHSAEVAGYQD 356

Query: 366 NIARLEEEIRHLKDEMARHLREYQDLLNVKMALDVEIATYRKLLEGEESRINLPIQTYSA 425
           +I +LE ++R+ K EMARHLREYQDLLNVKMALD+EIA YRKLLEGEE+R +    + S 
Sbjct: 357 SIGQLENDLRNTKSEMARHLREYQDLLNVKMALDIEIAAYRKLLEGEETRFSTSGLSISG 416

Query: 426 LN 427
           LN
Sbjct: 417 LN 418


>gi|105990539 neurofilament, light polypeptide 68kDa [Homo sapiens]
          Length = 543

 Score =  348 bits (894), Expect = 5e-96
 Identities = 204/458 (44%), Positives = 283/458 (61%), Gaps = 29/458 (6%)

Query: 36  PRAGFGSKGSSSSVTSRVYQVSRTSGGAGGLGSLRASRLGTTRTPSSYGAGELLDFSLAD 95
           PR    S  S  S     Y    +S  A    SL   R  ++ + S   + E LD S   
Sbjct: 22  PRVHISSVRSGYSTARSAY----SSYSAPVSSSLSVRRSYSSSSGSLMPSLENLDLSQVA 77

Query: 96  AVNQEFLTTRTNEKVELQELNDRFANYIEKVRFLEQQNAALAAE--VNRLKGREPTRVAE 153
           A++ +  + RT EK +LQ+LNDRFA++IE+V  LEQQN  L AE  V R K  EP+R   
Sbjct: 78  AISNDLKSIRTQEKAQLQDLNDRFASFIERVHELEQQNKVLEAELLVLRQKHSEPSRFRA 137

Query: 154 LYEEELRELRRQVEVLTNQRARVDVERDNLLDDLQRLKAKLQEEIQLKEEAENNLAAFRA 213
           LYE+E+R+LR   E  TN++  +  ER+ L + L+ L+A+ +EE+  +E+AE  L   R 
Sbjct: 138 LYEQEIRDLRLAAEDATNEKQALQGEREGLEETLRNLQARYEEEVLSREDAEGRLMEARK 197

Query: 214 DVDAATLARIDLERRIESLNEEIAFLKKVHEEEIRELQAQLQEQQVQVEMDMSKPDLTAA 273
             D A LAR +LE+RI+SL +EI+FLKKVHEEEI ELQAQ+Q  Q+ VEMD++KPDL+AA
Sbjct: 198 GADEAALARAELEKRIDSLMDEISFLKKVHEEEIAELQAQIQYAQISVEMDVTKPDLSAA 257

Query: 274 LRDIRAQYETIAAKNISEAEEWYKSKVSDLTQAANKNNDALRQAKQEMMEYRHQIQSYTC 333
           L+DIRAQYE +AAKN+  AEEW+KS+ + LT++A KN DA+R AK E+ E R  +++ T 
Sbjct: 258 LKDIRAQYEKLAAKNMQNAEEWFKSRFTVLTESAAKNTDAVRAAKDEVSESRRLLKAKTL 317

Query: 334 EIDALKGTNDSLMRQMRELEDRFASEASGYQDNIARLEEEIRHLKDEMARHLREYQDLLN 393
           EI+A +G N++L +Q++ELED+  ++ S  QD I +LE E+R  K EMAR+L+EYQDLLN
Sbjct: 318 EIEACRGMNEALEKQLQELEDKQNADISAMQDTINKLENELRTTKSEMARYLKEYQDLLN 377

Query: 394 VKMALDVEIATYRKLLEGEESRINLP-----------------------IQTYSALNFRE 430
           VKMALD+EIA YRKLLEGEE+R++                         +QT S L    
Sbjct: 378 VKMALDIEIAAYRKLLEGEETRLSFTSVGSITSGYSQSSQVFGRSAYGGLQTSSYLMSTR 437

Query: 431 TSPEQRGSEVHTKKTVMIKTIETRDGEVVSEATQQQHE 468
           + P    S V  ++  + +TIE    E   +    + E
Sbjct: 438 SFPSYYTSHVQEEQIEVEETIEAAKAEEAKDEPPSEGE 475


>gi|157738649 neurofilament, medium polypeptide 150kDa isoform 1
           [Homo sapiens]
          Length = 916

 Score =  322 bits (824), Expect = 6e-88
 Identities = 185/479 (38%), Positives = 299/479 (62%), Gaps = 25/479 (5%)

Query: 1   MSQAYSSSQRVSSYRRTFGGAPGFPLGSPLSSPVFPRAGFGSKGSSSSVTSRVYQVSRTS 60
           MS    S    S+YRR       F   S   S  F R+   S+GS S+V+S   +     
Sbjct: 1   MSYTLDSLGNPSAYRRVTETRSSFSRVSGSPSSGF-RSQSWSRGSPSTVSSSYKR----- 54

Query: 61  GGAGGLGSLRASRLGTTRTPSSYGAGELLDFSLADAV-------NQEFLTTRTNEKVELQ 113
                  S+ A RL  +    S  A   LDFS + ++         ++  +R+NEK +LQ
Sbjct: 55  -------SMLAPRLAYSSAMLS-SAESSLDFSQSSSLLNGGSGPGGDYKLSRSNEKEQLQ 106

Query: 114 ELNDRFANYIEKVRFLEQQNAALAAEVNRLKGREPT--RVAELYEEELRELRRQVEVLTN 171
            LNDRFA YIEKV +LEQQN  + AE+  L+ ++ +  ++ + Y++E+RELR  +E++ +
Sbjct: 107 GLNDRFAGYIEKVHYLEQQNKEIEAEIQALRQKQASHAQLGDAYDQEIRELRATLEMVNH 166

Query: 172 QRARVDVERDNLLDDLQRLKAKLQEEIQLKEEAENNLAAFRADVDAATLARIDLERRIES 231
           ++A+V ++ D+L +D+ RLK + +EE +L+++ E  + A R D++ A+L +++L+++++S
Sbjct: 167 EKAQVQLDSDHLEEDIHRLKERFEEEARLRDDTEAAIRALRKDIEEASLVKVELDKKVQS 226

Query: 232 LNEEIAFLKKVHEEEIRELQAQLQEQQVQVEM-DMSKPDLTAALRDIRAQYETIAAKNIS 290
           L +E+AFL+  HEEE+ +L AQ+Q   + VE  D  K D++ AL++IR+Q E+ + +N+ 
Sbjct: 227 LQDEVAFLRSNHEEEVADLLAQIQASHITVERKDYLKTDISTALKEIRSQLESHSDQNMH 286

Query: 291 EAEEWYKSKVSDLTQAANKNNDALRQAKQEMMEYRHQIQSYTCEIDALKGTNDSLMRQMR 350
           +AEEW+K + + LT+AA +N +A+R AK+E+ EYR Q+QS + E+++++GT +SL RQ+ 
Sbjct: 287 QAEEWFKCRYAKLTEAAEQNKEAIRSAKEEIAEYRRQLQSKSIELESVRGTKESLERQLS 346

Query: 351 ELEDRFASEASGYQDNIARLEEEIRHLKDEMARHLREYQDLLNVKMALDVEIATYRKLLE 410
           ++E+R   + S YQD I +LE E+R  K EMARHLREYQDLLNVKMALD+EIA YRKLLE
Sbjct: 347 DIEERHNHDLSSYQDTIQQLENELRGTKWEMARHLREYQDLLNVKMALDIEIAAYRKLLE 406

Query: 411 GEESRINLPIQTYSALNFRETSPEQRGSEVHTKKTVMIK-TIETRDGEVVSEATQQQHE 468
           GEE+R +    + +   +    P    S++   K    K  ++ +  E + E T+ + E
Sbjct: 407 GEETRFSTFAGSITGPLYTHRPPITISSKIQKPKVEAPKLKVQHKFVEEIIEETKVEDE 465


>gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens]
          Length = 1020

 Score =  283 bits (725), Expect = 2e-76
 Identities = 192/484 (39%), Positives = 273/484 (56%), Gaps = 47/484 (9%)

Query: 17  TFGGAPGFPLGSPLSSPVFPRAGFGSKGSSSSVTSRVYQVSRTSGGAGGLGSLRASRLGT 76
           +FGGA        L +P  P  G GS           Y ++R  GGAGG  S   S  G 
Sbjct: 3   SFGGADAL-----LGAPFAPLHGGGSLH---------YALAR-KGGAGGTRSAAGSSSGF 47

Query: 77  ---TRT--------PSSY-GAGELLDFSLADAVNQE------FLTTRTNEKVELQELNDR 118
              TRT        PS + GAG        D ++         + T  +EK +LQ LNDR
Sbjct: 48  HSWTRTSVSSVSASPSRFRGAGAASSTDSLDTLSNGPEGCMVAVATSRSEKEQLQALNDR 107

Query: 119 FANYIEKVRFLEQQNAALAAEVNRLKGREPTRVA--ELYEEELRELRRQVEVLTNQRARV 176
           FA YI+KVR LE  N +L  E   L+ ++  R A  ELYE E+RE+R  V  L   R ++
Sbjct: 108 FAGYIDKVRQLEAHNRSLEGEAAALRQQQAGRSAMGELYEREVREMRGAVLRLGAARGQL 167

Query: 177 DVERDNLLDDLQRLKAKLQEEIQLKEEAENNLAAFRADVDAATLARIDLERRIESLNEEI 236
            +E+++LL+D+  ++ +L +E + +EEAE    A       A  AR+DL+++ ++L EE 
Sbjct: 168 RLEQEHLLEDIAHVRQRLDDEARQREEAEAAARALARFAQEAEAARVDLQKKAQALQEEC 227

Query: 237 AFLKKVHEEEIRELQAQLQ-----EQQVQVEM-DMSKPDLTAALRDIRAQYETIAAKNIS 290
            +L++ H+EE+ EL  Q+Q     + Q+Q E  D  K D+T+ALR+IRAQ E  A ++  
Sbjct: 228 GYLRRHHQEEVGELLGQIQGSGAAQAQMQAETRDALKCDVTSALREIRAQLEGHAVQSTL 287

Query: 291 EAEEWYKSKVSDLTQAANKNNDALRQAKQEMMEYRHQIQSYTCEIDALKGTNDSLMRQMR 350
           ++EEW++ ++  L++AA  N DA+R A++E+ EYR Q+Q+ T E++ALK T DSL RQ  
Sbjct: 288 QSEEWFRVRLDRLSEAAKVNTDAMRSAQEEITEYRRQLQARTTELEALKSTKDSLERQRS 347

Query: 351 ELEDRFASEASGYQDNIARLEEEIRHLKDEMARHLREYQDLLNVKMALDVEIATYRKLLE 410
           ELEDR  ++ + YQ+ I +L+ E+R+ K EMA  LREYQDLLNVKMALD+EIA YRKLLE
Sbjct: 348 ELEDRHQADIASYQEAIQQLDAELRNTKWEMAAQLREYQDLLNVKMALDIEIAAYRKLLE 407

Query: 411 GEESRINLPIQTYSALNFRETSPEQRGSEVHTKKTVMIKTIETRDGEVV-----SEATQQ 465
           GEE RI      +S        P    + +  K    IK +E  + E V     +E TQ 
Sbjct: 408 GEECRIGFGPIPFSLPEGLPKIPSV-STHIKVKSEEKIKVVEKSEKETVIVEEQTEETQV 466

Query: 466 QHEV 469
             EV
Sbjct: 467 TEEV 470


>gi|4504919 keratin 8 [Homo sapiens]
          Length = 483

 Score =  258 bits (660), Expect = 6e-69
 Identities = 171/483 (35%), Positives = 263/483 (54%), Gaps = 45/483 (9%)

Query: 13  SYRRTFGGAPGFPLGSPLSSPVFPRAGFGSKGSSSSVTSRVYQVSRTSGGAGGLGSLRAS 72
           SY+ +  G   F   S  S P       GS+ SSSS  SRV   +   G  GG G   AS
Sbjct: 9   SYKVSTSGPRAFSSRSYTSGP-------GSRISSSSF-SRVGSSNFRGGLGGGYGG--AS 58

Query: 73  RLGTTRTPSSYGAGELLDFSLADAVNQEFLTTRTNEKVELQELNDRFANYIEKVRFLEQQ 132
            +G     ++    + L   L   V+      RT EK +++ LN++FA++I+KVRFLEQQ
Sbjct: 59  GMGGI---TAVTVNQSLLSPLVLEVDPNIQAVRTQEKEQIKTLNNKFASFIDKVRFLEQQ 115

Query: 133 NAALAAEVNRLKGREPTR--VAELYEEELRELRRQVEVLTNQRARVDVERDNLLDDLQRL 190
           N  L  + + L+ ++  R  +  ++E  +  LRRQ+E L  ++ +++ E  N+   ++  
Sbjct: 116 NKMLETKWSLLQQQKTARSNMDNMFESYINNLRRQLETLGQEKLKLEAELGNMQGLVEDF 175

Query: 191 KAKLQEEIQLKEEAENNLAAFRADVDAATLARIDLERRIESLNEEIAFLKKVHEEEIREL 250
           K K ++EI  + E EN     + DVD A + +++LE R+E L +EI FL++++EEEIREL
Sbjct: 176 KNKYEDEINKRTEMENEFVLIKKDVDEAYMNKVELESRLEGLTDEINFLRQLYEEEIREL 235

Query: 251 QAQLQEQQVQVEMDMSKP-DLTAALRDIRAQYETIAAKNISEAEEWYKSKVSDLTQAANK 309
           Q+Q+ +  V + MD S+  D+ + + +++AQYE IA ++ +EAE  Y+ K  +L   A K
Sbjct: 236 QSQISDTSVVLSMDNSRSLDMDSIIAEVKAQYEDIANRSRAEAESMYQIKYEELQSLAGK 295

Query: 310 NNDALRQAKQEMMEYRHQIQSYTCEIDALKGTNDSLMRQMRELEDRFASEASGYQDNIAR 369
           + D LR+ K E+ E    I     EI+ LKG   SL   + + E R           ++ 
Sbjct: 296 HGDDLRRTKTEISEMNRNISRLQAEIEGLKGQRASLEAAIADAEQRGELAIKDANAKLSE 355

Query: 370 LEEEIRHLKDEMARHLREYQDLLNVKMALDVEIATYRKLLEGEESRI-----NLPIQTYS 424
           LE  ++  K +MAR LREYQ+L+NVK+ALD+EIATYRKLLEGEESR+     N+ I T +
Sbjct: 356 LEAALQRAKQDMARQLREYQELMNVKLALDIEIATYRKLLEGEESRLESGMQNMSIHTKT 415

Query: 425 ALNFRE---------TSP---------------EQRGSEVHTKKTVMIKTIETRDGEVVS 460
              +           TSP                   S   + + V++K IETRDG++VS
Sbjct: 416 TSGYAGGLSSAYGGLTSPGLSYSLGSSFGSGAGSSSFSRTSSSRAVVVKKIETRDGKLVS 475

Query: 461 EAT 463
           E++
Sbjct: 476 ESS 478


>gi|153791158 keratin 75 [Homo sapiens]
          Length = 551

 Score =  237 bits (605), Expect = 1e-62
 Identities = 151/430 (35%), Positives = 236/430 (54%), Gaps = 37/430 (8%)

Query: 10  RVSSYRRTFGGAPGFPLGSPLSSPVFP-----RAGFGSKGSSSSVTSRVYQVSRTSGGAG 64
           R+SS   +FG    + LG      +       R+GFG + S+       + V+   G  G
Sbjct: 49  RISSAGASFGSRSLYNLGGAKRVSINGCGSSCRSGFGGRASNR------FGVNSGFGYGG 102

Query: 65  GLGSLRASRLGTTRTPSSYGAGELLDFSLADAVNQEFLT------------TRTNEKVEL 112
           G+G   +        P   G  E+        VNQ  LT             R  E+ ++
Sbjct: 103 GVGGGFSGPSFPVCPPG--GIQEV-------TVNQSLLTPLHLQIDPTIQRVRAEEREQI 153

Query: 113 QELNDRFANYIEKVRFLEQQNAALAAEVNRLKGREPTRVAE----LYEEELRELRRQVEV 168
           + LN++FA++I+KVRFLEQQN  L  +   L+ +    V +    L++    ELRRQ+E 
Sbjct: 154 KTLNNKFASFIDKVRFLEQQNKVLETKWALLQEQGSRTVRQNLEPLFDSYTSELRRQLES 213

Query: 169 LTNQRARVDVERDNLLDDLQRLKAKLQEEIQLKEEAENNLAAFRADVDAATLARIDLERR 228
           +T +R R++ E  N+ D ++  K + ++EI  +  AEN   A + DVDAA + +++LE +
Sbjct: 214 ITTERGRLEAELRNMQDVVEDFKVRYEDEINKRTAAENEFVALKKDVDAAYMNKVELEAK 273

Query: 229 IESLNEEIAFLKKVHEEEIRELQAQLQEQQVQVEMDMSKP-DLTAALRDIRAQYETIAAK 287
           ++SL EEI F+  V + E+ +LQ Q+ +  V + MD ++  DL + + +++AQYE IA +
Sbjct: 274 VKSLPEEINFIHSVFDAELSQLQTQVGDTSVVLSMDNNRNLDLDSIIAEVKAQYEDIANR 333

Query: 288 NISEAEEWYKSKVSDLTQAANKNNDALRQAKQEMMEYRHQIQSYTCEIDALKGTNDSLMR 347
           + +EAE WY++K  +L   A ++ D LR  KQE+ E    IQ    EID++K    SL  
Sbjct: 334 SRAEAESWYQTKYEELQVTAGRHGDDLRNTKQEISEMNRMIQRLRAEIDSVKKQCSSLQT 393

Query: 348 QMRELEDRFASEASGYQDNIARLEEEIRHLKDEMARHLREYQDLLNVKMALDVEIATYRK 407
            + + E R        +  +  LEE ++  K +MAR LREYQ+L+N+K+ALDVEIATYRK
Sbjct: 394 AIADAEQRGELALKDARAKLVDLEEALQKAKQDMARLLREYQELMNIKLALDVEIATYRK 453

Query: 408 LLEGEESRIN 417
           LLEGEE R++
Sbjct: 454 LLEGEECRLS 463


>gi|67782365 keratin 7 [Homo sapiens]
          Length = 469

 Score =  235 bits (599), Expect = 7e-62
 Identities = 147/406 (36%), Positives = 227/406 (55%), Gaps = 28/406 (6%)

Query: 31  SSPVFPRAGFGSKGSSSSVTSRVYQVSRTSGGAGGLGSLRASRLGTTR----TPSSYGAG 86
           SSPVF          S++ + R  QV  +S   GGLGS     LG +R      S+YG G
Sbjct: 6   SSPVFT-------SRSAAFSGRGAQVRLSSARPGGLGSSSLYGLGASRPRVAVRSAYG-G 57

Query: 87  ELLDFSLADAVNQEFLT------------TRTNEKVELQELNDRFANYIEKVRFLEQQNA 134
            +        +NQ  L              R  E  +++ LN++FA++I+KVRFLEQQN 
Sbjct: 58  PVGAGIREVTINQSLLAPLRLDADPSLQRVRQEESEQIKTLNNKFASFIDKVRFLEQQNK 117

Query: 135 ALAAEVNRL---KGREPTRVAELYEEELRELRRQVEVLTNQRARVDVERDNLLDDLQRLK 191
            L  +   L   K  + +R+ +++E ++  LR Q+E L     R++ E  ++ D ++  K
Sbjct: 118 LLETKWTLLQEQKSAKSSRLPDIFEAQIAGLRGQLEALQVDGGRLEAELRSMQDVVEDFK 177

Query: 192 AKLQEEIQLKEEAENNLAAFRADVDAATLARIDLERRIESLNEEIAFLKKVHEEEIRELQ 251
            K ++EI  +  AEN     + DVDAA +++++LE ++++LN+EI FL+ ++E E+ ELQ
Sbjct: 178 NKYEDEINHRTAAENEFVVLKKDVDAAYMSKVELEAKVDALNDEINFLRTLNETELTELQ 237

Query: 252 AQLQEQQVQVEMDMSKP-DLTAALRDIRAQYETIAAKNISEAEEWYKSKVSDLTQAANKN 310
           +Q+ +  V + MD S+  DL   + +++AQYE +A  + +EAE WY++K   L   A K+
Sbjct: 238 SQISDTSVVLSMDNSRSLDLDGIIAEVKAQYEEMAKCSRAEAEAWYQTKFETLQAQAGKH 297

Query: 311 NDALRQAKQEMMEYRHQIQSYTCEIDALKGTNDSLMRQMRELEDRFASEASGYQDNIARL 370
            D LR  + E+ E    IQ    EID +K     L   + E E+R        +     L
Sbjct: 298 GDDLRNTRNEISEMNRAIQRLQAEIDNIKNQRAKLEAAIAEAEERGELALKDARAKQEEL 357

Query: 371 EEEIRHLKDEMARHLREYQDLLNVKMALDVEIATYRKLLEGEESRI 416
           E  ++  K +MAR LREYQ+L++VK+ALD+EIATYRKLLEGEESR+
Sbjct: 358 EAALQRGKQDMARQLREYQELMSVKLALDIEIATYRKLLEGEESRL 403


>gi|119395754 keratin 5 [Homo sapiens]
          Length = 590

 Score =  231 bits (588), Expect = 1e-60
 Identities = 127/338 (37%), Positives = 203/338 (60%), Gaps = 17/338 (5%)

Query: 97  VNQEFLT------------TRTNEKVELQELNDRFANYIEKVRFLEQQNAALAAEVNRLK 144
           VNQ  LT             RT E+ +++ LN++FA++I+KVRFLEQQN  L  +   L+
Sbjct: 145 VNQSLLTPLNLQIDPSIQRVRTEEREQIKTLNNKFASFIDKVRFLEQQNKVLDTKWTLLQ 204

Query: 145 GREPTRVAE----LYEEELRELRRQVEVLTNQRARVDVERDNLLDDLQRLKAKLQEEIQL 200
            +    V +    L+E+ +  LRRQ++ +  +R R+D E  N+ D ++  K K ++EI  
Sbjct: 205 EQGTKTVRQNLEPLFEQYINNLRRQLDSIVGERGRLDSELRNMQDLVEDFKNKYEDEINK 264

Query: 201 KEEAENNLAAFRADVDAATLARIDLERRIESLNEEIAFLKKVHEEEIRELQAQLQEQQVQ 260
           +  AEN     + DVDAA + +++LE ++++L +EI F+K   + E+ ++Q  + +  V 
Sbjct: 265 RTTAENEFVMLKKDVDAAYMNKVELEAKVDALMDEINFMKMFFDAELSQMQTHVSDTSVV 324

Query: 261 VEMDMSKP-DLTAALRDIRAQYETIAAKNISEAEEWYKSKVSDLTQAANKNNDALRQAKQ 319
           + MD ++  DL + + +++AQYE IA ++ +EAE WY++K  +L Q A ++ D LR  K 
Sbjct: 325 LSMDNNRNLDLDSIIAEVKAQYEEIANRSRTEAESWYQTKYEELQQTAGRHGDDLRNTKH 384

Query: 320 EMMEYRHQIQSYTCEIDALKGTNDSLMRQMRELEDRFASEASGYQDNIARLEEEIRHLKD 379
           E+ E    IQ    EID +K    +L   + + E R        ++ +A LEE ++  K 
Sbjct: 385 EISEMNRMIQRLRAEIDNVKKQCANLQNAIADAEQRGELALKDARNKLAELEEALQKAKQ 444

Query: 380 EMARHLREYQDLLNVKMALDVEIATYRKLLEGEESRIN 417
           +MAR LREYQ+L+N K+ALDVEIATYRKLLEGEE R++
Sbjct: 445 DMARLLREYQELMNTKLALDVEIATYRKLLEGEECRLS 482


>gi|155969697 keratin 6C [Homo sapiens]
          Length = 564

 Score =  229 bits (583), Expect = 5e-60
 Identities = 139/406 (34%), Positives = 225/406 (55%), Gaps = 27/406 (6%)

Query: 18  FGGA-PGFPLGSPLSSPVFPRAGFGSKGSSSSVTSRVYQVSRTSGGAGGLGSLRASRLGT 76
           FGGA  GF  G           GFG  G +             +GG GG G       G 
Sbjct: 93  FGGAGSGFGFGGGAG------IGFGLGGGAG-----------LAGGFGGPGFPVCPPGGI 135

Query: 77  TRTPSSYGAGELLDFSLADAVNQEFLTTRTNEKVELQELNDRFANYIEKVRFLEQQNAAL 136
                +      L+  +  A+ +     R  E+ +++ LN++FA++I+KVRFLEQQN  L
Sbjct: 136 QEVTVNQSLLTPLNLQIDPAIQR----VRAEEREQIKTLNNKFASFIDKVRFLEQQNKVL 191

Query: 137 AAEVNRLKGREPTRVAE----LYEEELRELRRQVEVLTNQRARVDVERDNLLDDLQRLKA 192
             +   L+ +    V +    L+E+ +  LRRQ++ +  +R R+D E  N+ D ++ LK 
Sbjct: 192 DTKWTLLQEQGTKTVRQNLEPLFEQYINNLRRQLDSIVGERGRLDSELRNMQDLVEDLKN 251

Query: 193 KLQEEIQLKEEAENNLAAFRADVDAATLARIDLERRIESLNEEIAFLKKVHEEEIRELQA 252
           K ++EI  +  AEN     + DVDAA + +++L+ + ++L +EI FL+ +++ E+ ++Q 
Sbjct: 252 KYEDEINKRTAAENEFVTLKKDVDAAYMNKVELQAKADTLTDEINFLRALYDAELSQMQT 311

Query: 253 QLQEQQVQVEMDMSKP-DLTAALRDIRAQYETIAAKNISEAEEWYKSKVSDLTQAANKNN 311
            + +  V + MD ++  DL + + +++AQYE IA ++ +EAE WY++K  +L   A ++ 
Sbjct: 312 HISDTSVVLSMDNNRNLDLDSIIAEVKAQYEEIAQRSRAEAESWYQTKYEELQVTAGRHG 371

Query: 312 DALRQAKQEMMEYRHQIQSYTCEIDALKGTNDSLMRQMRELEDRFASEASGYQDNIARLE 371
           D LR  KQE+ E    IQ    EID +K    SL   + + E R        ++ +  LE
Sbjct: 372 DDLRNTKQEIAEINRMIQRLRSEIDHVKKQCASLQAAIADAEQRGEMALKDAKNKLEGLE 431

Query: 372 EEIRHLKDEMARHLREYQDLLNVKMALDVEIATYRKLLEGEESRIN 417
           + ++  K ++AR L+EYQ+L+NVK+ALDVEIATYRKLLEGEE R+N
Sbjct: 432 DALQKAKQDLARLLKEYQELMNVKLALDVEIATYRKLLEGEECRLN 477


>gi|15431316 keratin, hair, basic, 4 [Homo sapiens]
          Length = 600

 Score =  227 bits (578), Expect = 2e-59
 Identities = 136/363 (37%), Positives = 215/363 (59%), Gaps = 10/363 (2%)

Query: 62  GAGGLG-SLRASRLGTTRTPSSYGAGELLDFSLADAVNQEF----LTTRTNEKVELQELN 116
           G GG G   R   +G    PS       ++ SL   +N E        + +EK +++ LN
Sbjct: 116 GFGGPGFGYRVGGVGVPAAPSITAV--TVNKSLLTPLNLEIDPNAQRVKKDEKEQIKTLN 173

Query: 117 DRFANYIEKVRFLEQQNAALAAEVNRLKGREPTR--VAELYEEELRELRRQVEVLTNQRA 174
           ++FA++I+KVRFLEQQN  L  + + L+ ++  R  +  L+E  +  LRRQ+EVL + +A
Sbjct: 174 NKFASFIDKVRFLEQQNKLLETKWSFLQEQKCIRSNLEPLFESYITNLRRQLEVLVSDQA 233

Query: 175 RVDVERDNLLDDLQRLKAKLQEEIQLKEEAENNLAAFRADVDAATLARIDLERRIESLNE 234
           R+  ER++L D L+  K K +EE+  +  AEN   A + DVDAA + + DLE  +++L +
Sbjct: 234 RLQAERNHLQDVLEGFKKKYEEEVVCRANAENEFVALKKDVDAAFMNKSDLEANVDTLTQ 293

Query: 235 EIAFLKKVHEEEIRELQAQLQEQQVQVEMDMSKP-DLTAALRDIRAQYETIAAKNISEAE 293
           EI FLK ++ EEI+ LQ+ + E  V V+MD S+  +L   + +++AQYE +A ++ ++AE
Sbjct: 294 EIDFLKTLYMEEIQLLQSHISETSVIVKMDNSRDLNLDGIIAEVKAQYEEVARRSRADAE 353

Query: 294 EWYKSKVSDLTQAANKNNDALRQAKQEMMEYRHQIQSYTCEIDALKGTNDSLMRQMRELE 353
            WY++K  ++   A ++ D LR  + E+ E    IQ    EI+  K     L   + E E
Sbjct: 354 AWYQTKYEEMQVTAGQHCDNLRNIRNEINELTRLIQRLKAEIEHAKAQRAKLEAAVAEAE 413

Query: 354 DRFASEASGYQDNIARLEEEIRHLKDEMARHLREYQDLLNVKMALDVEIATYRKLLEGEE 413
            +  +  S  +  +A LE  ++  K +MAR L EYQ+L+N K+ LD+EIATYR+LLEGEE
Sbjct: 414 QQGEATLSDAKCKLADLECALQQAKQDMARQLCEYQELMNAKLGLDIEIATYRRLLEGEE 473

Query: 414 SRI 416
           SR+
Sbjct: 474 SRL 476


>gi|119703753 keratin 6B [Homo sapiens]
          Length = 564

 Score =  227 bits (578), Expect = 2e-59
 Identities = 138/406 (33%), Positives = 225/406 (55%), Gaps = 27/406 (6%)

Query: 18  FGGA-PGFPLGSPLSSPVFPRAGFGSKGSSSSVTSRVYQVSRTSGGAGGLGSLRASRLGT 76
           FGGA  GF  G           GFG  G +             +GG GG G       G 
Sbjct: 93  FGGAGSGFGFGGGAG------IGFGLGGGAG-----------LAGGFGGPGFPVCPPGGI 135

Query: 77  TRTPSSYGAGELLDFSLADAVNQEFLTTRTNEKVELQELNDRFANYIEKVRFLEQQNAAL 136
                +      L+  +  A+ +     R  E+ +++ LN++FA++I+KVRFLEQQN  L
Sbjct: 136 QEVTVNQSLLTPLNLQIDPAIQR----VRAEEREQIKTLNNKFASFIDKVRFLEQQNKVL 191

Query: 137 AAEVNRLKGREPTRVAE----LYEEELRELRRQVEVLTNQRARVDVERDNLLDDLQRLKA 192
             +   L+ +    V +    L+E+ +  LRRQ++ +  +R R+D E  N+ D ++ LK 
Sbjct: 192 DTKWTLLQEQGTKTVRQNLEPLFEQYINNLRRQLDNIVGERGRLDSELRNMQDLVEDLKN 251

Query: 193 KLQEEIQLKEEAENNLAAFRADVDAATLARIDLERRIESLNEEIAFLKKVHEEEIRELQA 252
           K ++EI  +  AEN     + DVDAA + +++L+ + ++L +EI FL+ +++ E+ ++Q 
Sbjct: 252 KYEDEINKRTAAENEFVTLKKDVDAAYMNKVELQAKADTLTDEINFLRALYDAELSQMQT 311

Query: 253 QLQEQQVQVEMDMSKP-DLTAALRDIRAQYETIAAKNISEAEEWYKSKVSDLTQAANKNN 311
            + +  V + MD ++  DL + + +++AQYE IA ++ +EAE WY++K  +L   A ++ 
Sbjct: 312 HISDTSVVLSMDNNRNLDLDSIIAEVKAQYEEIAQRSRAEAESWYQTKYEELQITAGRHG 371

Query: 312 DALRQAKQEMMEYRHQIQSYTCEIDALKGTNDSLMRQMRELEDRFASEASGYQDNIARLE 371
           D LR  KQE+ E    IQ    EID +K    +L   + + E R        ++ +  LE
Sbjct: 372 DDLRNTKQEIAEINRMIQRLRSEIDHVKKQCANLQAAIADAEQRGEMALKDAKNKLEGLE 431

Query: 372 EEIRHLKDEMARHLREYQDLLNVKMALDVEIATYRKLLEGEESRIN 417
           + ++  K ++AR L+EYQ+L+NVK+ALDVEIATYRKLLEGEE R+N
Sbjct: 432 DALQKAKQDLARLLKEYQELMNVKLALDVEIATYRKLLEGEECRLN 477


>gi|109255249 keratin 4 [Homo sapiens]
          Length = 594

 Score =  224 bits (572), Expect = 1e-58
 Identities = 121/326 (37%), Positives = 201/326 (61%), Gaps = 5/326 (1%)

Query: 97  VNQEFLTTRTNEKVELQELNDRFANYIEKVRFLEQQNAALAAEVNRLKGREPTRVAE--- 153
           ++ E    RT E+ +++ LN++FA++I+KV+FLEQQN  L  + N L+ +  T  ++   
Sbjct: 200 IDPEIQKVRTEEREQIKLLNNKFASFIDKVQFLEQQNKVLETKWNLLQQQTTTTSSKNLE 259

Query: 154 -LYEEELRELRRQVEVLTNQRARVDVERDNLLDDLQRLKAKLQEEIQLKEEAENNLAAFR 212
            L+E  L  LR+Q++ L N + R+  E   + D ++  K K +EEI  +  AEN+    +
Sbjct: 260 PLFETYLSVLRKQLDTLGNDKGRLQSELKTMQDSVEDFKTKYEEEINKRTAAENDFVVLK 319

Query: 213 ADVDAATLARIDLERRIESLNEEIAFLKKVHEEEIRELQAQLQEQQVQVEMDMSKP-DLT 271
            DVDAA L +++LE +++SLN+EI FLK +++ E+ ++Q  + +  V + MD ++  DL 
Sbjct: 320 KDVDAAYLNKVELEAKVDSLNDEINFLKVLYDAELSQMQTHVSDTSVVLSMDNNRNLDLD 379

Query: 272 AALRDIRAQYETIAAKNISEAEEWYKSKVSDLTQAANKNNDALRQAKQEMMEYRHQIQSY 331
           + + ++RAQYE IA ++ +EAE  Y++KV  L  + +++ D L+  K E+ E    IQ  
Sbjct: 380 SIIAEVRAQYEEIAQRSKAEAEALYQTKVQQLQISVDQHGDNLKNTKSEIAELNRMIQRL 439

Query: 332 TCEIDALKGTNDSLMRQMRELEDRFASEASGYQDNIARLEEEIRHLKDEMARHLREYQDL 391
             EI+ +K    +L   + + E R  +           LE  ++  K+E+AR LREYQ+L
Sbjct: 440 RAEIENIKKQCQTLQVSVADAEQRGENALKDAHSKRVELEAALQQAKEELARMLREYQEL 499

Query: 392 LNVKMALDVEIATYRKLLEGEESRIN 417
           ++VK+ALD+EIATYRKLLEGEE R++
Sbjct: 500 MSVKLALDIEIATYRKLLEGEEYRMS 525


>gi|109148552 keratin 3 [Homo sapiens]
          Length = 628

 Score =  224 bits (572), Expect = 1e-58
 Identities = 136/425 (32%), Positives = 228/425 (53%), Gaps = 28/425 (6%)

Query: 12  SSYRRTFGGAPGFPLGSPLSSPVFPRAGFGSKGSSSSVTSRVYQVSRTSGGAGGLGSLRA 71
           S Y   FGG  GF  G  +        GFG  G         +      GG+GG G    
Sbjct: 99  SGYGGGFGG--GFGGGRGMGGGFGGAGGFGGAGGFGGAGG--FGGPGGFGGSGGFGGP-- 152

Query: 72  SRLGTTRTPSSYGAGELLDFSLADAVNQEFLT------------TRTNEKVELQELNDRF 119
              G+  +P  +G G          +NQ  L              +  E+ +++ LN++F
Sbjct: 153 ---GSLGSPGGFGPGGFPGGIQEVTINQSLLQPLNVEIDPQIGQVKAQEREQIKTLNNKF 209

Query: 120 ANYIEKVRFLEQQNAALAAEVNRLKGREPTRVA------ELYEEELRELRRQVEVLTNQR 173
           A++I+KVRFLEQQN  L  + N L+ +  + ++       L+E  +  LR  ++ +  +R
Sbjct: 210 ASFIDKVRFLEQQNKVLETKWNLLQQQGTSSISGTNNLEPLFENHINYLRSYLDNILGER 269

Query: 174 ARVDVERDNLLDDLQRLKAKLQEEIQLKEEAENNLAAFRADVDAATLARIDLERRIESLN 233
            R+D E  N+ D ++  K K ++EI  +  AEN     + DVD+A + +++L+ ++++L 
Sbjct: 270 GRLDSELKNMEDLVEDFKKKYEDEINKRTAAENEFVTLKKDVDSAYMNKVELQAKVDALI 329

Query: 234 EEIAFLKKVHEEEIRELQAQLQEQQVQVEMDMSKP-DLTAALRDIRAQYETIAAKNISEA 292
           +EI FL+ +++ E+ ++Q+ + +  V + MD ++  DL + + ++RAQYE IA ++ +EA
Sbjct: 330 DEIDFLRTLYDAELSQMQSHISDTSVVLSMDNNRSLDLDSIIAEVRAQYEDIAQRSKAEA 389

Query: 293 EEWYKSKVSDLTQAANKNNDALRQAKQEMMEYRHQIQSYTCEIDALKGTNDSLMRQMREL 352
           E  Y++K+ +L   A ++ D LR  K E++E    IQ    EI+ +K  N +L   + E 
Sbjct: 390 EALYQTKLGELQTTAGRHGDDLRNTKSEIIELNRMIQRLRAEIEGVKKQNANLQTAIAEA 449

Query: 353 EDRFASEASGYQDNIARLEEEIRHLKDEMARHLREYQDLLNVKMALDVEIATYRKLLEGE 412
           E             +  L+  ++  KD++AR LR+YQ+L+NVK+ALDVEIATYRKLLEGE
Sbjct: 450 EQHGEMALKDANAKLQELQAALQQAKDDLARLLRDYQELMNVKLALDVEIATYRKLLEGE 509

Query: 413 ESRIN 417
           E R++
Sbjct: 510 EYRMS 514


>gi|5031839 keratin 6A [Homo sapiens]
          Length = 564

 Score =  224 bits (570), Expect = 2e-58
 Identities = 122/338 (36%), Positives = 202/338 (59%), Gaps = 17/338 (5%)

Query: 97  VNQEFLT------------TRTNEKVELQELNDRFANYIEKVRFLEQQNAALAAEVNRLK 144
           VNQ  LT             R  E+ +++ LN++FA++I+KVRFLEQQN  L  +   L+
Sbjct: 140 VNQSLLTPLNLQIDPTIQRVRAEEREQIKTLNNKFASFIDKVRFLEQQNKVLETKWTLLQ 199

Query: 145 GREPTRVAE----LYEEELRELRRQVEVLTNQRARVDVERDNLLDDLQRLKAKLQEEIQL 200
            +    V +    L+E+ +  LRRQ++ +  +R R+D E   + D ++  K K ++EI  
Sbjct: 200 EQGTKTVRQNLEPLFEQYINNLRRQLDSIVGERGRLDSELRGMQDLVEDFKNKYEDEINK 259

Query: 201 KEEAENNLAAFRADVDAATLARIDLERRIESLNEEIAFLKKVHEEEIRELQAQLQEQQVQ 260
           +  AEN     + DVDAA + +++L+ + ++L +EI FL+ +++ E+ ++Q  + +  V 
Sbjct: 260 RTAAENEFVTLKKDVDAAYMNKVELQAKADTLTDEINFLRALYDAELSQMQTHISDTSVV 319

Query: 261 VEMDMSKP-DLTAALRDIRAQYETIAAKNISEAEEWYKSKVSDLTQAANKNNDALRQAKQ 319
           + MD ++  DL + + +++AQYE IA ++ +EAE WY++K  +L   A ++ D LR  KQ
Sbjct: 320 LSMDNNRNLDLDSIIAEVKAQYEEIAQRSRAEAESWYQTKYEELQVTAGRHGDDLRNTKQ 379

Query: 320 EMMEYRHQIQSYTCEIDALKGTNDSLMRQMRELEDRFASEASGYQDNIARLEEEIRHLKD 379
           E+ E    IQ    EID +K    +L   + + E R        ++ +  LE+ ++  K 
Sbjct: 380 EIAEINRMIQRLRSEIDHVKKQCANLQAAIADAEQRGEMALKDAKNKLEGLEDALQKAKQ 439

Query: 380 EMARHLREYQDLLNVKMALDVEIATYRKLLEGEESRIN 417
           ++AR L+EYQ+L+NVK+ALDVEIATYRKLLEGEE R+N
Sbjct: 440 DLARLLKEYQELMNVKLALDVEIATYRKLLEGEECRLN 477


>gi|153791670 keratin 76 [Homo sapiens]
          Length = 638

 Score =  222 bits (566), Expect = 5e-58
 Identities = 141/426 (33%), Positives = 231/426 (54%), Gaps = 28/426 (6%)

Query: 6   SSSQRVSSYRRTFGGA--PGFPLGSPLSSPVFPRAGFGSKGSSSSVTSRVYQVSRTSGGA 63
           SS      Y   FGG+   GF  G  + S      GFG  G        V+    + GG 
Sbjct: 86  SSCGFAGGYGGGFGGSYGGGFGGGRGVGSGFGGAGGFGGAGGFGG--PGVFGGPGSFGGP 143

Query: 64  GGLGSLRASRLGTTRTPSSYGAG---ELLDFSLADAVNQEFLT----TRTNEKVELQELN 116
           GG G            P  +  G    +++ SL   +N E        +  E+ +++ LN
Sbjct: 144 GGFG------------PGGFPGGIQEVIVNQSLLQPLNVEIDPQIGQVKAQEREQIKTLN 191

Query: 117 DRFANYIEKVRFLEQQNAALAAEVNRLK----GREPTRVAELYEEELRELRRQVEVLTNQ 172
           ++FA++I+KVRFLEQQN  L  +   L+    G  P+ +   +E  +  L +Q++ L  +
Sbjct: 192 NKFASFIDKVRFLEQQNKVLETKWELLQQQTTGSGPSSLEPCFESYISFLCKQLDSLLGE 251

Query: 173 RARVDVERDNLLDDLQRLKAKLQEEIQLKEEAENNLAAFRADVDAATLARIDLERRIESL 232
           R  ++ E  ++ D ++  K K ++EI  +  AEN     + DVDAA + +++L+ +++SL
Sbjct: 252 RGNLEGELKSMQDLVEDFKKKYEDEINKRTAAENEFVGLKKDVDAAFMNKVELQAKVDSL 311

Query: 233 NEEIAFLKKVHEEEIRELQAQLQEQQVQVEMDMSKP-DLTAALRDIRAQYETIAAKNISE 291
            +E++FL+ ++E E+ ++Q+   +  V + MD ++  DL + + ++RAQYE IA ++ SE
Sbjct: 312 TDEVSFLRTLYEMELSQMQSHASDTSVVLSMDNNRCLDLGSIIAEVRAQYEEIAQRSKSE 371

Query: 292 AEEWYKSKVSDLTQAANKNNDALRQAKQEMMEYRHQIQSYTCEIDALKGTNDSLMRQMRE 351
           AE  Y++K+ +L   A ++ D LR  K E+ME    IQ    EI+ +K  N +L   + E
Sbjct: 372 AEALYQTKLGELQTTAGRHGDDLRNTKSEIMELNRMIQRLRAEIENVKKQNANLQTAIAE 431

Query: 352 LEDRFASEASGYQDNIARLEEEIRHLKDEMARHLREYQDLLNVKMALDVEIATYRKLLEG 411
            E R           +  L+  ++  KD++AR LR+YQ+L+NVK+ALDVEIATYRKLLEG
Sbjct: 432 AEQRGEMALKDANAKLQDLQTALQKAKDDLARLLRDYQELMNVKLALDVEIATYRKLLEG 491

Query: 412 EESRIN 417
           EE R++
Sbjct: 492 EECRMS 497



 Score = 32.0 bits (71), Expect = 1.2
 Identities = 30/90 (33%), Positives = 38/90 (42%), Gaps = 14/90 (15%)

Query: 1   MSQAYSSSQRVSSYRRTFGGAPGFPLGSPLSSPVFPRAGFGSKGSSSSVTSRVYQVSRTS 60
           +S   S+S    S R  FGG  G   G             G KG SSS +S  Y VS  S
Sbjct: 509 VSNVTSTSGSSGSSRGVFGGVSGSGSG-------------GYKGGSSSSSSSGYGVSGGS 555

Query: 61  G-GAGGLGSLRASRLGTTRTPSSYGAGELL 89
           G G GG+ S      G++ +  S  +G  L
Sbjct: 556 GSGYGGVSSGSTGGRGSSGSYQSSSSGSRL 585


>gi|119395750 keratin 1 [Homo sapiens]
          Length = 644

 Score =  221 bits (562), Expect = 1e-57
 Identities = 138/420 (32%), Positives = 227/420 (54%), Gaps = 29/420 (6%)

Query: 19  GGAPGFPLGSPLSSPVFPRAGFGSKGSSSSVTSRVYQVSRTSGGAGGLGSLRASRLGTTR 78
           GG  G   G       F   GFG  G                GG GG GS      G   
Sbjct: 83  GGGRGSGFGGGYGGGGFGGGGFGGGGFGGGGIG--------GGGFGGFGSGGGGFGGGGF 134

Query: 79  TPSSYGAGE------------LLDFSLADAVN----QEFLTTRTNEKVELQELNDRFANY 122
               YG G              ++ SL   +N     E    ++ E+ +++ LN++FA++
Sbjct: 135 GGGGYGGGYGPVCPPGGIQEVTINQSLLQPLNVEIDPEIQKVKSREREQIKSLNNQFASF 194

Query: 123 IEKVRFLEQQNAALAAEVNRLKGREP-TRVAEL---YEEELRELRRQVEVLTNQRARVDV 178
           I+KVRFLEQQN  L  +   L+  +  TR   L   +E  +  LRR+V+ L + ++R+D 
Sbjct: 195 IDKVRFLEQQNQVLQTKWELLQQVDTSTRTHNLEPYFESFINNLRRRVDQLKSDQSRLDS 254

Query: 179 ERDNLLDDLQRLKAKLQEEIQLKEEAENNLAAFRADVDAATLARIDLERRIESLNEEIAF 238
           E  N+ D ++  + K ++EI  +  AEN     + DVD A + ++DL+ ++++L +EI F
Sbjct: 255 ELKNMQDMVEDYRNKYEDEINKRTNAENEFVTIKKDVDGAYMTKVDLQAKLDNLQQEIDF 314

Query: 239 LKKVHEEEIRELQAQLQEQQVQVEMDMSKP-DLTAALRDIRAQYETIAAKNISEAEEWYK 297
           L  +++ E+ ++Q Q+ E  V + MD ++  DL + + +++AQYE IA K+ +EAE  Y+
Sbjct: 315 LTALYQAELSQMQTQISETNVILSMDNNRSLDLDSIIAEVKAQYEDIAQKSKAEAESLYQ 374

Query: 298 SKVSDLTQAANKNNDALRQAKQEMMEYRHQIQSYTCEIDALKGTNDSLMRQMRELEDRFA 357
           SK  +L   A ++ D++R +K E+ E    IQ    EID +K    +L + + + E R  
Sbjct: 375 SKYEELQITAGRHGDSVRNSKIEISELNRVIQRLRSEIDNVKKQISNLQQSISDAEQRGE 434

Query: 358 SEASGYQDNIARLEEEIRHLKDEMARHLREYQDLLNVKMALDVEIATYRKLLEGEESRIN 417
           +     ++ +  LE+ ++  K+++AR LR+YQ+L+N K+ALD+EIATYR LLEGEESR++
Sbjct: 435 NALKDAKNKLNDLEDALQQAKEDLARLLRDYQELMNTKLALDLEIATYRTLLEGEESRMS 494


>gi|32567786 keratin 6L [Homo sapiens]
          Length = 535

 Score =  219 bits (557), Expect = 5e-57
 Identities = 157/467 (33%), Positives = 233/467 (49%), Gaps = 69/467 (14%)

Query: 10  RVSSYRRTFGGAPGFPLGSPLSSPVFPRAGFGSKGSSSSVTSRVYQVSRTSG-------- 61
           R S  R+T+    GF   S         +G  ++ S SSVT     VSR+SG        
Sbjct: 2   RSSVSRQTYSTKGGFSSNSASGG-----SGSQARTSFSSVT-----VSRSSGSGGGAHCG 51

Query: 62  -GAGGLGSLRASRLGTTRTPS-SYGAGELLDFSLAD------------------------ 95
            G GG GS     LG  ++ S S   G LL  +L                          
Sbjct: 52  PGTGGFGSRSLYNLGGHKSISVSVAGGALLGRALGGFGFGSRAFMGQGAGRQTFGPACPP 111

Query: 96  ------AVNQEFLT------------TRTNEKVELQELNDRFANYIEKVRFLEQQNA--- 134
                  VNQ  LT             RT E+ +++ LN++FA++I+KVRFLEQQN    
Sbjct: 112 GGIQEVTVNQSLLTPLHVEIDPEIQRVRTQEREQIKTLNNKFASFIDKVRFLEQQNKVLE 171

Query: 135 ---ALAAEVNRLKGREPTRVAELYEEELRELRRQVEVLTNQRARVDVERDNLLDDLQRLK 191
              AL  E  +  G     +  L+E  L  +R  ++ L ++R R+D E  N+ D ++  K
Sbjct: 172 TKWALLQEQGQNLGVTRNNLEPLFEAYLGSMRSTLDRLQSERGRLDSELRNVQDLVEDFK 231

Query: 192 AKLQEEIQLKEEAENNLAAFRADVDAATLARIDLERRIESLNEEIAFLKKVHEEEIRELQ 251
            K ++EI     AEN     + DVDAA + R+DL  ++ +L +EI FL++++E E+ ++Q
Sbjct: 232 NKYEDEINKHTAAENEFVVLKKDVDAAYMGRMDLHGKVGTLTQEIDFLQQLYEMELSQVQ 291

Query: 252 AQLQEQQVQVEMDMSKP-DLTAALRDIRAQYETIAAKNISEAEEWYKSKVSDLTQAANKN 310
             +    V + MD ++  DL + + +++AQYE IA ++ +EAE WY++K  +L   A K+
Sbjct: 292 THVSNTNVVLSMDNNRNLDLDSIIAEVKAQYELIAQRSRAEAEAWYQTKYEELQVTAGKH 351

Query: 311 NDALRQAKQEMMEYRHQIQSYTCEIDALKGTNDSLMRQMRELEDRFASEASGYQDNIARL 370
            D LR  K E+ E    IQ    E DA K     L   + E E R        Q  +  L
Sbjct: 352 GDNLRDTKNEIAELTRTIQRLQGEADAAKKQCQQLQTAIAEAEQRGELALKDAQKKLGDL 411

Query: 371 EEEIRHLKDEMARHLREYQDLLNVKMALDVEIATYRKLLEGEESRIN 417
           +  +   K+++ R LR+YQ+L+NVK+ALDVEIATYRKLLE EESR++
Sbjct: 412 DVALHQAKEDLTRLLRDYQELMNVKLALDVEIATYRKLLESEESRMS 458


>gi|239755818 PREDICTED: hypothetical protein isoform 2 [Homo
           sapiens]
          Length = 486

 Score =  218 bits (556), Expect = 7e-57
 Identities = 134/399 (33%), Positives = 220/399 (55%), Gaps = 23/399 (5%)

Query: 41  GSKGSSSSVTSRVYQ-VSRTSGGAGGLGSLRAS---RLGTTRTPSSYGAGELLDFS---- 92
           G +     +T+  Y+ +S   G  GG GS       R G+      Y +G +   S    
Sbjct: 19  GPRPGRCCITAAPYRGISCYRGLTGGFGSHSVCGGFRAGSCGRSFGYRSGGVCGPSPPCI 78

Query: 93  LADAVNQEFLT------------TRTNEKVELQELNDRFANYIEKVRFLEQQNAALAAEV 140
              +VN+  LT             +  EK +++ LN RFA +I+KVRFLEQQN  L  ++
Sbjct: 79  TTVSVNESLLTPLNLEIDPNAQCVKQEEKEQIKSLNSRFAAFIDKVRFLEQQNKLLETKL 138

Query: 141 NRLKGRE--PTRVAELYEEELRELRRQVEVLTNQRARVDVERDNLLDDLQRLKAKLQEEI 198
              + RE   + +  L+E  +  LRR+ E +     R+  E +++ + L+  K K +EE+
Sbjct: 139 QFYQNRECCQSNLEPLFEGYIETLRREAECVEADSGRLASELNHVQEVLEGYKKKYEEEV 198

Query: 199 QLKEEAENNLAAFRADVDAATLARIDLERRIESLNEEIAFLKKVHEEEIRELQAQLQEQQ 258
            L+  AEN   A + DVD A L + DLE  +E+L +EI FL++++EEEIR LQ+ + +  
Sbjct: 199 SLRATAENEFVALKKDVDCAYLRKSDLEANVEALIQEIDFLRRLYEEEIRVLQSHISDTS 258

Query: 259 VQVEMDMSKP-DLTAALRDIRAQYETIAAKNISEAEEWYKSKVSDLTQAANKNNDALRQA 317
           V V++D S+  ++   + +I+AQY+ I  ++ +EAE WY+SK  ++     ++ + LR+ 
Sbjct: 259 VVVKLDNSRDLNMDCIIAEIKAQYDDIVTRSRAEAESWYRSKCEEMKATVIRHGETLRRT 318

Query: 318 KQEMMEYRHQIQSYTCEIDALKGTNDSLMRQMRELEDRFASEASGYQDNIARLEEEIRHL 377
           K+E+ E    IQ  T E++  K  N  L   + + E +  +  S  +  +A LE  ++  
Sbjct: 319 KEEINELNRMIQRLTAEVENAKCQNSKLEAAVAQSEQQGEAALSDARCKLAELEGALQKA 378

Query: 378 KDEMARHLREYQDLLNVKMALDVEIATYRKLLEGEESRI 416
           K +MA  +REYQ+++N K+ LD+EIATYR+LLEGEE R+
Sbjct: 379 KQDMACLIREYQEVMNSKLGLDIEIATYRRLLEGEEQRL 417


>gi|239755816 PREDICTED: hypothetical protein isoform 1 [Homo
           sapiens]
          Length = 486

 Score =  218 bits (556), Expect = 7e-57
 Identities = 134/399 (33%), Positives = 220/399 (55%), Gaps = 23/399 (5%)

Query: 41  GSKGSSSSVTSRVYQ-VSRTSGGAGGLGSLRAS---RLGTTRTPSSYGAGELLDFS---- 92
           G +     +T+  Y+ +S   G  GG GS       R G+      Y +G +   S    
Sbjct: 19  GPRPGRCCITAAPYRGISCYRGLTGGFGSHSVCGGFRAGSCGRSFGYRSGGVCGPSPPCI 78

Query: 93  LADAVNQEFLT------------TRTNEKVELQELNDRFANYIEKVRFLEQQNAALAAEV 140
              +VN+  LT             +  EK +++ LN RFA +I+KVRFLEQQN  L  ++
Sbjct: 79  TTVSVNESLLTPLNLEIDPNAQCVKQEEKEQIKSLNSRFAAFIDKVRFLEQQNKLLETKL 138

Query: 141 NRLKGRE--PTRVAELYEEELRELRRQVEVLTNQRARVDVERDNLLDDLQRLKAKLQEEI 198
              + RE   + +  L+E  +  LRR+ E +     R+  E +++ + L+  K K +EE+
Sbjct: 139 QFYQNRECCQSNLEPLFEGYIETLRREAECVEADSGRLASELNHVQEVLEGYKKKYEEEV 198

Query: 199 QLKEEAENNLAAFRADVDAATLARIDLERRIESLNEEIAFLKKVHEEEIRELQAQLQEQQ 258
            L+  AEN   A + DVD A L + DLE  +E+L +EI FL++++EEEIR LQ+ + +  
Sbjct: 199 SLRATAENEFVALKKDVDCAYLRKSDLEANVEALIQEIDFLRRLYEEEIRVLQSHISDTS 258

Query: 259 VQVEMDMSKP-DLTAALRDIRAQYETIAAKNISEAEEWYKSKVSDLTQAANKNNDALRQA 317
           V V++D S+  ++   + +I+AQY+ I  ++ +EAE WY+SK  ++     ++ + LR+ 
Sbjct: 259 VVVKLDNSRDLNMDCIIAEIKAQYDDIVTRSRAEAESWYRSKCEEMKATVIRHGETLRRT 318

Query: 318 KQEMMEYRHQIQSYTCEIDALKGTNDSLMRQMRELEDRFASEASGYQDNIARLEEEIRHL 377
           K+E+ E    IQ  T E++  K  N  L   + + E +  +  S  +  +A LE  ++  
Sbjct: 319 KEEINELNRMIQRLTAEVENAKCQNSKLEAAVAQSEQQGEAALSDARCKLAELEGALQKA 378

Query: 378 KDEMARHLREYQDLLNVKMALDVEIATYRKLLEGEESRI 416
           K +MA  +REYQ+++N K+ LD+EIATYR+LLEGEE R+
Sbjct: 379 KQDMACLIREYQEVMNSKLGLDIEIATYRRLLEGEEQRL 417


>gi|239755814 PREDICTED: hypothetical protein isoform 3 [Homo
           sapiens]
          Length = 486

 Score =  218 bits (556), Expect = 7e-57
 Identities = 134/399 (33%), Positives = 220/399 (55%), Gaps = 23/399 (5%)

Query: 41  GSKGSSSSVTSRVYQ-VSRTSGGAGGLGSLRAS---RLGTTRTPSSYGAGELLDFS---- 92
           G +     +T+  Y+ +S   G  GG GS       R G+      Y +G +   S    
Sbjct: 19  GPRPGRCCITAAPYRGISCYRGLTGGFGSHSVCGGFRAGSCGRSFGYRSGGVCGPSPPCI 78

Query: 93  LADAVNQEFLT------------TRTNEKVELQELNDRFANYIEKVRFLEQQNAALAAEV 140
              +VN+  LT             +  EK +++ LN RFA +I+KVRFLEQQN  L  ++
Sbjct: 79  TTVSVNESLLTPLNLEIDPNAQCVKQEEKEQIKSLNSRFAAFIDKVRFLEQQNKLLETKL 138

Query: 141 NRLKGRE--PTRVAELYEEELRELRRQVEVLTNQRARVDVERDNLLDDLQRLKAKLQEEI 198
              + RE   + +  L+E  +  LRR+ E +     R+  E +++ + L+  K K +EE+
Sbjct: 139 QFYQNRECCQSNLEPLFEGYIETLRREAECVEADSGRLASELNHVQEVLEGYKKKYEEEV 198

Query: 199 QLKEEAENNLAAFRADVDAATLARIDLERRIESLNEEIAFLKKVHEEEIRELQAQLQEQQ 258
            L+  AEN   A + DVD A L + DLE  +E+L +EI FL++++EEEIR LQ+ + +  
Sbjct: 199 SLRATAENEFVALKKDVDCAYLRKSDLEANVEALIQEIDFLRRLYEEEIRVLQSHISDTS 258

Query: 259 VQVEMDMSKP-DLTAALRDIRAQYETIAAKNISEAEEWYKSKVSDLTQAANKNNDALRQA 317
           V V++D S+  ++   + +I+AQY+ I  ++ +EAE WY+SK  ++     ++ + LR+ 
Sbjct: 259 VVVKLDNSRDLNMDCIIAEIKAQYDDIVTRSRAEAESWYRSKCEEMKATVIRHGETLRRT 318

Query: 318 KQEMMEYRHQIQSYTCEIDALKGTNDSLMRQMRELEDRFASEASGYQDNIARLEEEIRHL 377
           K+E+ E    IQ  T E++  K  N  L   + + E +  +  S  +  +A LE  ++  
Sbjct: 319 KEEINELNRMIQRLTAEVENAKCQNSKLEAAVAQSEQQGEAALSDARCKLAELEGALQKA 378

Query: 378 KDEMARHLREYQDLLNVKMALDVEIATYRKLLEGEESRI 416
           K +MA  +REYQ+++N K+ LD+EIATYR+LLEGEE R+
Sbjct: 379 KQDMACLIREYQEVMNSKLGLDIEIATYRRLLEGEEQRL 417


>gi|14318422 keratin 86 [Homo sapiens]
          Length = 486

 Score =  218 bits (556), Expect = 7e-57
 Identities = 134/399 (33%), Positives = 220/399 (55%), Gaps = 23/399 (5%)

Query: 41  GSKGSSSSVTSRVYQ-VSRTSGGAGGLGSLRAS---RLGTTRTPSSYGAGELLDFS---- 92
           G +     +T+  Y+ +S   G  GG GS       R G+      Y +G +   S    
Sbjct: 19  GPRPGRCCITAAPYRGISCYRGLTGGFGSHSVCGGFRAGSCGRSFGYRSGGVCGPSPPCI 78

Query: 93  LADAVNQEFLT------------TRTNEKVELQELNDRFANYIEKVRFLEQQNAALAAEV 140
              +VN+  LT             +  EK +++ LN RFA +I+KVRFLEQQN  L  ++
Sbjct: 79  TTVSVNESLLTPLNLEIDPNAQCVKQEEKEQIKSLNSRFAAFIDKVRFLEQQNKLLETKL 138

Query: 141 NRLKGRE--PTRVAELYEEELRELRRQVEVLTNQRARVDVERDNLLDDLQRLKAKLQEEI 198
              + RE   + +  L+E  +  LRR+ E +     R+  E +++ + L+  K K +EE+
Sbjct: 139 QFYQNRECCQSNLEPLFEGYIETLRREAECVEADSGRLASELNHVQEVLEGYKKKYEEEV 198

Query: 199 QLKEEAENNLAAFRADVDAATLARIDLERRIESLNEEIAFLKKVHEEEIRELQAQLQEQQ 258
            L+  AEN   A + DVD A L + DLE  +E+L +EI FL++++EEEIR LQ+ + +  
Sbjct: 199 SLRATAENEFVALKKDVDCAYLRKSDLEANVEALIQEIDFLRRLYEEEIRVLQSHISDTS 258

Query: 259 VQVEMDMSKP-DLTAALRDIRAQYETIAAKNISEAEEWYKSKVSDLTQAANKNNDALRQA 317
           V V++D S+  ++   + +I+AQY+ I  ++ +EAE WY+SK  ++     ++ + LR+ 
Sbjct: 259 VVVKLDNSRDLNMDCIIAEIKAQYDDIVTRSRAEAESWYRSKCEEMKATVIRHGETLRRT 318

Query: 318 KQEMMEYRHQIQSYTCEIDALKGTNDSLMRQMRELEDRFASEASGYQDNIARLEEEIRHL 377
           K+E+ E    IQ  T E++  K  N  L   + + E +  +  S  +  +A LE  ++  
Sbjct: 319 KEEINELNRMIQRLTAEVENAKCQNSKLEAAVAQSEQQGEAALSDARCKLAELEGALQKA 378

Query: 378 KDEMARHLREYQDLLNVKMALDVEIATYRKLLEGEESRI 416
           K +MA  +REYQ+++N K+ LD+EIATYR+LLEGEE R+
Sbjct: 379 KQDMACLIREYQEVMNSKLGLDIEIATYRRLLEGEEQRL 417


>gi|169790841 keratin 83 [Homo sapiens]
          Length = 493

 Score =  218 bits (555), Expect = 9e-57
 Identities = 135/399 (33%), Positives = 221/399 (55%), Gaps = 23/399 (5%)

Query: 41  GSKGSSSSVTSRVYQ-VSRTSGGAGGLGSLRAS---RLGTTRTPSSYGAGELLDFS---- 92
           G + S   +T+  Y+ +S   G  GG GS       R G+      Y +G +   S    
Sbjct: 24  GPRPSRCCITAAPYRGISCYRGLTGGFGSHSVCGGFRAGSCGRSFGYRSGGVCGPSPPCI 83

Query: 93  LADAVNQEFLT------------TRTNEKVELQELNDRFANYIEKVRFLEQQNAALAAEV 140
              +VN+  LT             +  EK +++ LN RFA +I+KVRFLEQQN  L  ++
Sbjct: 84  TTVSVNESLLTPLNLEIDPNAQCVKQEEKEQIKSLNSRFAAFIDKVRFLEQQNKLLETKL 143

Query: 141 NRLKGRE--PTRVAELYEEELRELRRQVEVLTNQRARVDVERDNLLDDLQRLKAKLQEEI 198
              + RE   + +  L+   +  LRR+ E +     R+  E +++ + L+  K K +EE+
Sbjct: 144 QFYQNRECCQSNLEPLFAGYIETLRREAECVEADSGRLASELNHVQEVLEGYKKKYEEEV 203

Query: 199 QLKEEAENNLAAFRADVDAATLARIDLERRIESLNEEIAFLKKVHEEEIRELQAQLQEQQ 258
            L+  AEN   A + DVD A L + DLE  +E+L +EI FL++++EEEIR LQ+ + +  
Sbjct: 204 ALRATAENEFVALKKDVDCAYLRKSDLEANVEALIQEIDFLRRLYEEEIRILQSHISDTS 263

Query: 259 VQVEMDMSKP-DLTAALRDIRAQYETIAAKNISEAEEWYKSKVSDLTQAANKNNDALRQA 317
           V V++D S+  ++   + +I+AQY+ IA ++ +EAE WY+SK  ++     ++ + LR+ 
Sbjct: 264 VVVKLDNSRDLNMDCIVAEIKAQYDDIATRSRAEAESWYRSKCEEMKATVIRHGETLRRT 323

Query: 318 KQEMMEYRHQIQSYTCEIDALKGTNDSLMRQMRELEDRFASEASGYQDNIARLEEEIRHL 377
           K+E+ E    IQ  T E++  K  N  L   + + E +  +  S  +  +A LE  ++  
Sbjct: 324 KEEINELNRMIQRLTAEVENAKCQNSKLEAAVAQSEQQGEAALSDARCKLAELEGALQKA 383

Query: 378 KDEMARHLREYQDLLNVKMALDVEIATYRKLLEGEESRI 416
           K +MA  +REYQ+++N K+ LD+EIATYR+LLEGEE R+
Sbjct: 384 KQDMACLIREYQEVMNSKLGLDIEIATYRRLLEGEEQRL 422


>gi|148612803 keratin 6 irs4 [Homo sapiens]
          Length = 529

 Score =  217 bits (553), Expect = 2e-56
 Identities = 149/468 (31%), Positives = 243/468 (51%), Gaps = 47/468 (10%)

Query: 38  AGFGSKGSSSSVTSRVYQVSRTSGG--AGGLGSLRASRLGTTRTP----SSYGAGEL--- 88
           AGFGS+   S   +R    +   GG  AGG G    S  G  R      S +G+  L   
Sbjct: 43  AGFGSRSLYSLGGNRRISFNVAGGGVRAGGYGFRPGSGYGGGRASGFAGSMFGSVALGPA 102

Query: 89  --------------LDFSLADAVN----QEFLTTRTNEKVELQELNDRFANYIEKVRFLE 130
                         ++ SL   +N     E    R  E+ +++ LND+FA++I+KVRFLE
Sbjct: 103 CLSVCPPGGIHQVTVNKSLLAPLNVELDPEIQKVRAQEREQIKVLNDKFASFIDKVRFLE 162

Query: 131 QQNAALAAEVNRLKGRE----PTRVAELYEEELRELRRQVEVLTNQRARVDVERDNLLDD 186
           QQN  L  +   L+  +       +  + E  +  LR+Q+E L+  R R+D E  ++ D 
Sbjct: 163 QQNQVLETKWELLQQLDLNNCKKNLEPILEGYISNLRKQLETLSGDRVRLDSELRSMRDL 222

Query: 187 LQRLKAKLQEEIQLKEEAENNLAAFRADVDAATLARIDLERRIESLNEEIAFLKKVHEEE 246
           ++  K + + EI  +  AEN     + D DAA   +++L+ +++SL++EI FLK +++ E
Sbjct: 223 VEDYKKRYEVEINRRTTAENEFVVLKKDADAAYAVKVELQAKVDSLDKEIKFLKCLYDAE 282

Query: 247 IRELQAQLQEQQVQVEMDMSKP-DLTAALRDIRAQYETIAAKNISEAEEWYKSKVSDLTQ 305
           I ++Q    E  V + MD ++  DL + + ++R  YE IA K+ +EAE  Y++K+ +L  
Sbjct: 283 IAQIQTHASETSVILSMDNNRDLDLDSIIAEVRMHYEEIALKSKAEAEALYQTKIQELQL 342

Query: 306 AANKNNDALRQAKQEMMEYRHQIQSYTCEIDALKGTNDSLMRQMRELEDRFASEASGYQD 365
           AA+++ D L+  + EM+E    IQ   CEI  +K    SL   + + E R  +     Q 
Sbjct: 343 AASRHGDDLKHTRSEMVELNRLIQRIRCEIGNVKKQRASLETAIADAEQRGDNALKDAQA 402

Query: 366 NIARLEEEIRHLKDEMARHLREYQDLLNVKMALDVEIATYRKLLEGEESRI------NLP 419
            +  LE  +   K+E+AR LREYQ+L+++K+ALD+EIATYRKLLEGEE R+      ++ 
Sbjct: 403 KLDELEGALHQAKEELARMLREYQELMSLKLALDMEIATYRKLLEGEECRMSGENPSSVS 462

Query: 420 IQTYSALNFRETSPEQRGSEV---------HTKKTVMIKTIETRDGEV 458
           I   S+ ++    P   G ++          + ++   KT E R G++
Sbjct: 463 ISVISSSSYSYHHPSSAGVDLGASAVAGSSGSTQSGQTKTTEARGGDL 510


>gi|27477127 keratin 82 [Homo sapiens]
          Length = 513

 Score =  216 bits (551), Expect = 3e-56
 Identities = 144/405 (35%), Positives = 219/405 (54%), Gaps = 21/405 (5%)

Query: 19  GGAPGFPLGSPLSSPVFPRAGFGSKGSSSSVTSRVYQVSRTSGGAGGLGSLRASRLGTTR 78
           GG  G      L S      GFG          R    SR  G   G G     RLG T 
Sbjct: 41  GGGRGLRALGCLGSRSLCNVGFG----------RPRVASRCGGTLPGFGY----RLGATC 86

Query: 79  TPSS----YGAGELLDFSLADAVNQEFLTTRTNEKVELQELNDRFANYIEKVRFLEQQNA 134
            PS+        E L   LA  ++      + +EK +++ LN+RFA++I KVRFLEQ+N 
Sbjct: 87  GPSACITPVTINESLLVPLALEIDPTVQRVKRDEKEQIKCLNNRFASFINKVRFLEQKNK 146

Query: 135 ALAAEVNRLKGRE--PTRVAELYEEELRELRRQVEVLTNQRARVDVERDNLLDDLQRLKA 192
            L  + N ++ +    T +  ++E  +  LRRQ++ ++  R R++ E  +L   L+  K 
Sbjct: 147 LLETKWNFMQQQRCCQTNIEPIFEGYISALRRQLDCVSGDRVRLESELCSLQAALEGYKK 206

Query: 193 KLQEEIQLKEEAENNLAAFRADVDAATLARIDLERRIESLNEEIAFLKKVHEEEIRELQA 252
           K +EE+ L+   EN   A + DVD A L + DLE   E+L +EI FLK ++EEEI  LQ+
Sbjct: 207 KYEEELSLRPCVENEFVALKKDVDTAFLMKADLETNAEALVQEIDFLKSLYEEEICLLQS 266

Query: 253 QLQEQQVQVEMDMSKP-DLTAALRDIRAQYETIAAKNISEAEEWYKSKVSDLTQAANKNN 311
           Q+ E  V V+MD S+  D+   + +I+AQY+ IA+++ +EAE WY+ +  +L   A  + 
Sbjct: 267 QISETSVIVKMDNSRELDVDGIIAEIKAQYDDIASRSKAEAEAWYQCRYEELRVTAGNHC 326

Query: 312 DALRQAKQEMMEYRHQIQSYTCEIDALKGTNDSLMRQMRELEDRFASEASGYQDNIARLE 371
           D LR  K E++E    IQ    E + +K     L   + E E +  +  +  +  +A LE
Sbjct: 327 DNLRNRKNEILEMNKLIQRLQQETENVKAQRCKLEGAIAEAEQQGEAALNDAKCKLAGLE 386

Query: 372 EEIRHLKDEMARHLREYQDLLNVKMALDVEIATYRKLLEGEESRI 416
           E ++  K +MA  L+EYQ+++N K+ LD+EIATYR+LLEGEE R+
Sbjct: 387 EALQKAKQDMACLLKEYQEVMNSKLGLDIEIATYRRLLEGEEHRL 431


>gi|169790853 keratin, hair, basic, 1 [Homo sapiens]
          Length = 505

 Score =  215 bits (548), Expect = 6e-56
 Identities = 133/399 (33%), Positives = 219/399 (54%), Gaps = 23/399 (5%)

Query: 41  GSKGSSSSVTSRVYQ-VSRTSGGAGGLGSLRAS---RLGTTRTPSSYGAGELLDFS---- 92
           G +     +T+  Y+ +S   G  GG GS       R G+      Y +G +   S    
Sbjct: 19  GPRPGRCCITAAPYRGISCYRGLTGGFGSHSVCGGFRAGSCGRSFGYRSGGVCGPSPPCI 78

Query: 93  LADAVNQEFLT------------TRTNEKVELQELNDRFANYIEKVRFLEQQNAALAAEV 140
              +VN+  LT             +  EK +++ LN RFA +I+KVRFLEQQN  L  ++
Sbjct: 79  TTVSVNESLLTPLNLEIDPNAQCVKQEEKEQIKSLNSRFAAFIDKVRFLEQQNKLLETKL 138

Query: 141 NRLKGRE--PTRVAELYEEELRELRRQVEVLTNQRARVDVERDNLLDDLQRLKAKLQEEI 198
              + RE   + +  L+E  +  LRR+ E +     R+  E +++ + L+  K K +EE+
Sbjct: 139 QFYQNRECCQSNLEPLFEGYIETLRREAECVEADSGRLASELNHVQEVLEGYKKKYEEEV 198

Query: 199 QLKEEAENNLAAFRADVDAATLARIDLERRIESLNEEIAFLKKVHEEEIRELQAQLQEQQ 258
            L+  AEN   A + DVD A L + DLE  +E+L +EI FL++++EEEI  LQ+ + +  
Sbjct: 199 SLRATAENEFVALKKDVDCAYLRKSDLEANVEALIQEIDFLRRLYEEEILILQSHISDTS 258

Query: 259 VQVEMDMSKP-DLTAALRDIRAQYETIAAKNISEAEEWYKSKVSDLTQAANKNNDALRQA 317
           V V++D S+  ++   + +I+AQY+ I  ++ +EAE WY+SK  ++     ++ + LR+ 
Sbjct: 259 VVVKLDNSRDLNMDCIIAEIKAQYDDIVTRSRAEAESWYRSKCEEMKATVIRHGETLRRT 318

Query: 318 KQEMMEYRHQIQSYTCEIDALKGTNDSLMRQMRELEDRFASEASGYQDNIARLEEEIRHL 377
           K+E+ E    IQ  T E++  K  N  L   + + E +  +  S  +  +A LE  ++  
Sbjct: 319 KEEINELNRMIQRLTAEVENAKCQNSKLEAAVAQSEQQGEAALSDARCKLAELEGALQKA 378

Query: 378 KDEMARHLREYQDLLNVKMALDVEIATYRKLLEGEESRI 416
           K +MA  +REYQ+++N K+ LD+EIATYR+LLEGEE R+
Sbjct: 379 KQDMACLIREYQEVMNSKLGLDIEIATYRRLLEGEEQRL 417


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.312    0.127    0.335 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 15,215,363
Number of Sequences: 37866
Number of extensions: 669377
Number of successful extensions: 7756
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 277
Number of HSP's successfully gapped in prelim test: 815
Number of HSP's that attempted gapping in prelim test: 4041
Number of HSP's gapped (non-prelim): 2633
length of query: 470
length of database: 18,247,518
effective HSP length: 106
effective length of query: 364
effective length of database: 14,233,722
effective search space: 5181074808
effective search space used: 5181074808
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.