Guide to the Human Genome
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Search of human proteins with 54144629

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|54144629 numb homolog isoform 4 [Homo sapiens]
         (592 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|54144629 numb homolog isoform 4 [Homo sapiens]                    1202   0.0  
gi|54144627 numb homolog isoform 2 [Homo sapiens]                    1193   0.0  
gi|20070356 numb homolog isoform 3 [Homo sapiens]                    1179   0.0  
gi|54144625 numb homolog isoform 1 [Homo sapiens]                    1170   0.0  
gi|10863899 numb homolog (Drosophila)-like [Homo sapiens]             597   e-170
gi|7705318 GULP, engulfment adaptor PTB domain containing 1 [Hom...    82   2e-15
gi|132626790 low density lipoprotein receptor adaptor protein 1 ...    77   3e-14
gi|33350928 disabled homolog 1 [Homo sapiens]                          65   2e-10
gi|50511947 cajalin 2 isoform b [Homo sapiens]                         59   1e-08
gi|50511945 cajalin 2 isoform a [Homo sapiens]                         59   1e-08
gi|10047134 cajalin 2 isoform c [Homo sapiens]                         59   1e-08
gi|140161500 ankyrin repeat and sterile alpha motif domain conta...    56   8e-08
gi|19718731 bromodomain-containing protein 4 isoform long [Homo ...    53   7e-07
gi|31317301 nitric oxide synthase 1 (neuronal) adaptor protein i...    51   3e-06
gi|148491082 disabled homolog 2 [Homo sapiens]                         51   3e-06
gi|21327715 transcription elongation regulator 1 isoform 1 [Homo...    50   6e-06
gi|149773456 hypothetical protein LOC643314 [Homo sapiens]             49   1e-05
gi|91208418 transcription elongation regulator 1 isoform 2 [Homo...    48   3e-05
gi|153792074 proline rich 12 [Homo sapiens]                            48   3e-05
gi|189181724 proteoglycan 4 isoform D [Homo sapiens]                   47   5e-05
gi|189181722 proteoglycan 4 isoform C [Homo sapiens]                   47   5e-05
gi|189181720 proteoglycan 4 isoform B [Homo sapiens]                   47   5e-05
gi|67190163 proteoglycan 4 isoform A [Homo sapiens]                    47   5e-05
gi|146219843 Snf2-related CBP activator protein [Homo sapiens]         47   6e-05
gi|91208420 bassoon protein [Homo sapiens]                             45   1e-04
gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapi...    45   2e-04
gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapi...    45   2e-04
gi|7662236 TSC22 domain family, member 2 [Homo sapiens]                44   3e-04
gi|222418647 mucin 7, secreted precursor [Homo sapiens]                44   4e-04
gi|222418649 mucin 7, secreted precursor [Homo sapiens]                44   4e-04

>gi|54144629 numb homolog isoform 4 [Homo sapiens]
          Length = 592

 Score = 1202 bits (3109), Expect = 0.0
 Identities = 592/592 (100%), Positives = 592/592 (100%)

Query: 1   MNKLRQSFRRKKDVYVPEASRPHQWQTDEEGVRTGKCSFPVKYLGHVEVDESRGMHICED 60
           MNKLRQSFRRKKDVYVPEASRPHQWQTDEEGVRTGKCSFPVKYLGHVEVDESRGMHICED
Sbjct: 1   MNKLRQSFRRKKDVYVPEASRPHQWQTDEEGVRTGKCSFPVKYLGHVEVDESRGMHICED 60

Query: 61  AVKRLKATGKKAVKAVLWVSADGLRVVDEKTKDLIVDQTIEKVSFCAPDRNFDRAFSYIC 120
           AVKRLKATGKKAVKAVLWVSADGLRVVDEKTKDLIVDQTIEKVSFCAPDRNFDRAFSYIC
Sbjct: 61  AVKRLKATGKKAVKAVLWVSADGLRVVDEKTKDLIVDQTIEKVSFCAPDRNFDRAFSYIC 120

Query: 121 RDGTTRRWICHCFMAVKDTGERLSHAVGCAFAACLERKQKREKECGVTATFDASRTTFTR 180
           RDGTTRRWICHCFMAVKDTGERLSHAVGCAFAACLERKQKREKECGVTATFDASRTTFTR
Sbjct: 121 RDGTTRRWICHCFMAVKDTGERLSHAVGCAFAACLERKQKREKECGVTATFDASRTTFTR 180

Query: 181 EGSFRVTTATEQAEREEIMKQMQDAKKAETDKIVVGSSVAPGNTAPSPSSPTSPTSDATT 240
           EGSFRVTTATEQAEREEIMKQMQDAKKAETDKIVVGSSVAPGNTAPSPSSPTSPTSDATT
Sbjct: 181 EGSFRVTTATEQAEREEIMKQMQDAKKAETDKIVVGSSVAPGNTAPSPSSPTSPTSDATT 240

Query: 241 SLEMNNPHAIPRRHAPIEQLARQGSFRGFPALSQKMSPFKRQLSLRINELPSTMQRKTDF 300
           SLEMNNPHAIPRRHAPIEQLARQGSFRGFPALSQKMSPFKRQLSLRINELPSTMQRKTDF
Sbjct: 241 SLEMNNPHAIPRRHAPIEQLARQGSFRGFPALSQKMSPFKRQLSLRINELPSTMQRKTDF 300

Query: 301 PIKNAVPEVEGEAESISSLCSQITNAFSTPEDPFSSAPMTKPVTVVAPQSPTFQGTEWGQ 360
           PIKNAVPEVEGEAESISSLCSQITNAFSTPEDPFSSAPMTKPVTVVAPQSPTFQGTEWGQ
Sbjct: 301 PIKNAVPEVEGEAESISSLCSQITNAFSTPEDPFSSAPMTKPVTVVAPQSPTFQGTEWGQ 360

Query: 361 SSGAASPGLFQAGHRRTPSEADRWLEEVSKSVRAQQPQASAAPLQPVLQPPPPTAISQPA 420
           SSGAASPGLFQAGHRRTPSEADRWLEEVSKSVRAQQPQASAAPLQPVLQPPPPTAISQPA
Sbjct: 361 SSGAASPGLFQAGHRRTPSEADRWLEEVSKSVRAQQPQASAAPLQPVLQPPPPTAISQPA 420

Query: 421 SPFQGNAFLTSQPVPVGVVPALQPAFVPAQSYPVANGMPYPAPNVPVVGITPSQMVANVF 480
           SPFQGNAFLTSQPVPVGVVPALQPAFVPAQSYPVANGMPYPAPNVPVVGITPSQMVANVF
Sbjct: 421 SPFQGNAFLTSQPVPVGVVPALQPAFVPAQSYPVANGMPYPAPNVPVVGITPSQMVANVF 480

Query: 481 GTAGHPQAAHPHQSPSLVRQQTFPHYEASSATTSPFFKPPAQHLNGSAAFNGVDDGRLAS 540
           GTAGHPQAAHPHQSPSLVRQQTFPHYEASSATTSPFFKPPAQHLNGSAAFNGVDDGRLAS
Sbjct: 481 GTAGHPQAAHPHQSPSLVRQQTFPHYEASSATTSPFFKPPAQHLNGSAAFNGVDDGRLAS 540

Query: 541 ADRHTEVPTGTCPVDPFEAQWAALENKSKQRTNPSPTNPFSSDLQKTFEIEL 592
           ADRHTEVPTGTCPVDPFEAQWAALENKSKQRTNPSPTNPFSSDLQKTFEIEL
Sbjct: 541 ADRHTEVPTGTCPVDPFEAQWAALENKSKQRTNPSPTNPFSSDLQKTFEIEL 592


>gi|54144627 numb homolog isoform 2 [Homo sapiens]
          Length = 603

 Score = 1193 bits (3087), Expect = 0.0
 Identities = 592/603 (98%), Positives = 592/603 (98%), Gaps = 11/603 (1%)

Query: 1   MNKLRQSFRRKKDVYVPEASRPHQWQTDEEGVRTGKCSFPVKYLGHVEVDESRGMHICED 60
           MNKLRQSFRRKKDVYVPEASRPHQWQTDEEGVRTGKCSFPVKYLGHVEVDESRGMHICED
Sbjct: 1   MNKLRQSFRRKKDVYVPEASRPHQWQTDEEGVRTGKCSFPVKYLGHVEVDESRGMHICED 60

Query: 61  AVKRLKA-----------TGKKAVKAVLWVSADGLRVVDEKTKDLIVDQTIEKVSFCAPD 109
           AVKRLKA           TGKKAVKAVLWVSADGLRVVDEKTKDLIVDQTIEKVSFCAPD
Sbjct: 61  AVKRLKAERKFFKGFFGKTGKKAVKAVLWVSADGLRVVDEKTKDLIVDQTIEKVSFCAPD 120

Query: 110 RNFDRAFSYICRDGTTRRWICHCFMAVKDTGERLSHAVGCAFAACLERKQKREKECGVTA 169
           RNFDRAFSYICRDGTTRRWICHCFMAVKDTGERLSHAVGCAFAACLERKQKREKECGVTA
Sbjct: 121 RNFDRAFSYICRDGTTRRWICHCFMAVKDTGERLSHAVGCAFAACLERKQKREKECGVTA 180

Query: 170 TFDASRTTFTREGSFRVTTATEQAEREEIMKQMQDAKKAETDKIVVGSSVAPGNTAPSPS 229
           TFDASRTTFTREGSFRVTTATEQAEREEIMKQMQDAKKAETDKIVVGSSVAPGNTAPSPS
Sbjct: 181 TFDASRTTFTREGSFRVTTATEQAEREEIMKQMQDAKKAETDKIVVGSSVAPGNTAPSPS 240

Query: 230 SPTSPTSDATTSLEMNNPHAIPRRHAPIEQLARQGSFRGFPALSQKMSPFKRQLSLRINE 289
           SPTSPTSDATTSLEMNNPHAIPRRHAPIEQLARQGSFRGFPALSQKMSPFKRQLSLRINE
Sbjct: 241 SPTSPTSDATTSLEMNNPHAIPRRHAPIEQLARQGSFRGFPALSQKMSPFKRQLSLRINE 300

Query: 290 LPSTMQRKTDFPIKNAVPEVEGEAESISSLCSQITNAFSTPEDPFSSAPMTKPVTVVAPQ 349
           LPSTMQRKTDFPIKNAVPEVEGEAESISSLCSQITNAFSTPEDPFSSAPMTKPVTVVAPQ
Sbjct: 301 LPSTMQRKTDFPIKNAVPEVEGEAESISSLCSQITNAFSTPEDPFSSAPMTKPVTVVAPQ 360

Query: 350 SPTFQGTEWGQSSGAASPGLFQAGHRRTPSEADRWLEEVSKSVRAQQPQASAAPLQPVLQ 409
           SPTFQGTEWGQSSGAASPGLFQAGHRRTPSEADRWLEEVSKSVRAQQPQASAAPLQPVLQ
Sbjct: 361 SPTFQGTEWGQSSGAASPGLFQAGHRRTPSEADRWLEEVSKSVRAQQPQASAAPLQPVLQ 420

Query: 410 PPPPTAISQPASPFQGNAFLTSQPVPVGVVPALQPAFVPAQSYPVANGMPYPAPNVPVVG 469
           PPPPTAISQPASPFQGNAFLTSQPVPVGVVPALQPAFVPAQSYPVANGMPYPAPNVPVVG
Sbjct: 421 PPPPTAISQPASPFQGNAFLTSQPVPVGVVPALQPAFVPAQSYPVANGMPYPAPNVPVVG 480

Query: 470 ITPSQMVANVFGTAGHPQAAHPHQSPSLVRQQTFPHYEASSATTSPFFKPPAQHLNGSAA 529
           ITPSQMVANVFGTAGHPQAAHPHQSPSLVRQQTFPHYEASSATTSPFFKPPAQHLNGSAA
Sbjct: 481 ITPSQMVANVFGTAGHPQAAHPHQSPSLVRQQTFPHYEASSATTSPFFKPPAQHLNGSAA 540

Query: 530 FNGVDDGRLASADRHTEVPTGTCPVDPFEAQWAALENKSKQRTNPSPTNPFSSDLQKTFE 589
           FNGVDDGRLASADRHTEVPTGTCPVDPFEAQWAALENKSKQRTNPSPTNPFSSDLQKTFE
Sbjct: 541 FNGVDDGRLASADRHTEVPTGTCPVDPFEAQWAALENKSKQRTNPSPTNPFSSDLQKTFE 600

Query: 590 IEL 592
           IEL
Sbjct: 601 IEL 603


>gi|20070356 numb homolog isoform 3 [Homo sapiens]
          Length = 640

 Score = 1179 bits (3050), Expect = 0.0
 Identities = 592/640 (92%), Positives = 592/640 (92%), Gaps = 48/640 (7%)

Query: 1   MNKLRQSFRRKKDVYVPEASRPHQWQTDEEGVRTGKCSFPVKYLGHVEVDESRGMHICED 60
           MNKLRQSFRRKKDVYVPEASRPHQWQTDEEGVRTGKCSFPVKYLGHVEVDESRGMHICED
Sbjct: 1   MNKLRQSFRRKKDVYVPEASRPHQWQTDEEGVRTGKCSFPVKYLGHVEVDESRGMHICED 60

Query: 61  AVKRLKATGKKAVKAVLWVSADGLRVVDEKTKDLIVDQTIEKVSFCAPDRNFDRAFSYIC 120
           AVKRLKATGKKAVKAVLWVSADGLRVVDEKTKDLIVDQTIEKVSFCAPDRNFDRAFSYIC
Sbjct: 61  AVKRLKATGKKAVKAVLWVSADGLRVVDEKTKDLIVDQTIEKVSFCAPDRNFDRAFSYIC 120

Query: 121 RDGTTRRWICHCFMAVKDTGERLSHAVGCAFAACLERKQKREKECGVTATFDASRTTFTR 180
           RDGTTRRWICHCFMAVKDTGERLSHAVGCAFAACLERKQKREKECGVTATFDASRTTFTR
Sbjct: 121 RDGTTRRWICHCFMAVKDTGERLSHAVGCAFAACLERKQKREKECGVTATFDASRTTFTR 180

Query: 181 EGSFRVTTATEQAEREEIMKQMQDAKKAETDKIVVGSSVAPGNTAPSPSSPTSPTSDATT 240
           EGSFRVTTATEQAEREEIMKQMQDAKKAETDKIVVGSSVAPGNTAPSPSSPTSPTSDATT
Sbjct: 181 EGSFRVTTATEQAEREEIMKQMQDAKKAETDKIVVGSSVAPGNTAPSPSSPTSPTSDATT 240

Query: 241 SLEMNNPHAIPRRHAPIEQLARQGSFRGFPALSQKMSPFKRQLSLRINELPSTMQRKTDF 300
           SLEMNNPHAIPRRHAPIEQLARQGSFRGFPALSQKMSPFKRQLSLRINELPSTMQRKTDF
Sbjct: 241 SLEMNNPHAIPRRHAPIEQLARQGSFRGFPALSQKMSPFKRQLSLRINELPSTMQRKTDF 300

Query: 301 PIKNAVPEVEGEAESISSLCSQITNAFSTPEDPFSSAPMTKPVTVVAPQSPTFQ------ 354
           PIKNAVPEVEGEAESISSLCSQITNAFSTPEDPFSSAPMTKPVTVVAPQSPTFQ      
Sbjct: 301 PIKNAVPEVEGEAESISSLCSQITNAFSTPEDPFSSAPMTKPVTVVAPQSPTFQANGTDS 360

Query: 355 ------------------------------------------GTEWGQSSGAASPGLFQA 372
                                                     GTEWGQSSGAASPGLFQA
Sbjct: 361 AFHVLAKPAHTALAPVAMPVRETNPWAHAPDAANKEIAATCSGTEWGQSSGAASPGLFQA 420

Query: 373 GHRRTPSEADRWLEEVSKSVRAQQPQASAAPLQPVLQPPPPTAISQPASPFQGNAFLTSQ 432
           GHRRTPSEADRWLEEVSKSVRAQQPQASAAPLQPVLQPPPPTAISQPASPFQGNAFLTSQ
Sbjct: 421 GHRRTPSEADRWLEEVSKSVRAQQPQASAAPLQPVLQPPPPTAISQPASPFQGNAFLTSQ 480

Query: 433 PVPVGVVPALQPAFVPAQSYPVANGMPYPAPNVPVVGITPSQMVANVFGTAGHPQAAHPH 492
           PVPVGVVPALQPAFVPAQSYPVANGMPYPAPNVPVVGITPSQMVANVFGTAGHPQAAHPH
Sbjct: 481 PVPVGVVPALQPAFVPAQSYPVANGMPYPAPNVPVVGITPSQMVANVFGTAGHPQAAHPH 540

Query: 493 QSPSLVRQQTFPHYEASSATTSPFFKPPAQHLNGSAAFNGVDDGRLASADRHTEVPTGTC 552
           QSPSLVRQQTFPHYEASSATTSPFFKPPAQHLNGSAAFNGVDDGRLASADRHTEVPTGTC
Sbjct: 541 QSPSLVRQQTFPHYEASSATTSPFFKPPAQHLNGSAAFNGVDDGRLASADRHTEVPTGTC 600

Query: 553 PVDPFEAQWAALENKSKQRTNPSPTNPFSSDLQKTFEIEL 592
           PVDPFEAQWAALENKSKQRTNPSPTNPFSSDLQKTFEIEL
Sbjct: 601 PVDPFEAQWAALENKSKQRTNPSPTNPFSSDLQKTFEIEL 640


>gi|54144625 numb homolog isoform 1 [Homo sapiens]
          Length = 651

 Score = 1170 bits (3028), Expect = 0.0
 Identities = 592/651 (90%), Positives = 592/651 (90%), Gaps = 59/651 (9%)

Query: 1   MNKLRQSFRRKKDVYVPEASRPHQWQTDEEGVRTGKCSFPVKYLGHVEVDESRGMHICED 60
           MNKLRQSFRRKKDVYVPEASRPHQWQTDEEGVRTGKCSFPVKYLGHVEVDESRGMHICED
Sbjct: 1   MNKLRQSFRRKKDVYVPEASRPHQWQTDEEGVRTGKCSFPVKYLGHVEVDESRGMHICED 60

Query: 61  AVKRLKA-----------TGKKAVKAVLWVSADGLRVVDEKTKDLIVDQTIEKVSFCAPD 109
           AVKRLKA           TGKKAVKAVLWVSADGLRVVDEKTKDLIVDQTIEKVSFCAPD
Sbjct: 61  AVKRLKAERKFFKGFFGKTGKKAVKAVLWVSADGLRVVDEKTKDLIVDQTIEKVSFCAPD 120

Query: 110 RNFDRAFSYICRDGTTRRWICHCFMAVKDTGERLSHAVGCAFAACLERKQKREKECGVTA 169
           RNFDRAFSYICRDGTTRRWICHCFMAVKDTGERLSHAVGCAFAACLERKQKREKECGVTA
Sbjct: 121 RNFDRAFSYICRDGTTRRWICHCFMAVKDTGERLSHAVGCAFAACLERKQKREKECGVTA 180

Query: 170 TFDASRTTFTREGSFRVTTATEQAEREEIMKQMQDAKKAETDKIVVGSSVAPGNTAPSPS 229
           TFDASRTTFTREGSFRVTTATEQAEREEIMKQMQDAKKAETDKIVVGSSVAPGNTAPSPS
Sbjct: 181 TFDASRTTFTREGSFRVTTATEQAEREEIMKQMQDAKKAETDKIVVGSSVAPGNTAPSPS 240

Query: 230 SPTSPTSDATTSLEMNNPHAIPRRHAPIEQLARQGSFRGFPALSQKMSPFKRQLSLRINE 289
           SPTSPTSDATTSLEMNNPHAIPRRHAPIEQLARQGSFRGFPALSQKMSPFKRQLSLRINE
Sbjct: 241 SPTSPTSDATTSLEMNNPHAIPRRHAPIEQLARQGSFRGFPALSQKMSPFKRQLSLRINE 300

Query: 290 LPSTMQRKTDFPIKNAVPEVEGEAESISSLCSQITNAFSTPEDPFSSAPMTKPVTVVAPQ 349
           LPSTMQRKTDFPIKNAVPEVEGEAESISSLCSQITNAFSTPEDPFSSAPMTKPVTVVAPQ
Sbjct: 301 LPSTMQRKTDFPIKNAVPEVEGEAESISSLCSQITNAFSTPEDPFSSAPMTKPVTVVAPQ 360

Query: 350 SPTFQ------------------------------------------------GTEWGQS 361
           SPTFQ                                                GTEWGQS
Sbjct: 361 SPTFQANGTDSAFHVLAKPAHTALAPVAMPVRETNPWAHAPDAANKEIAATCSGTEWGQS 420

Query: 362 SGAASPGLFQAGHRRTPSEADRWLEEVSKSVRAQQPQASAAPLQPVLQPPPPTAISQPAS 421
           SGAASPGLFQAGHRRTPSEADRWLEEVSKSVRAQQPQASAAPLQPVLQPPPPTAISQPAS
Sbjct: 421 SGAASPGLFQAGHRRTPSEADRWLEEVSKSVRAQQPQASAAPLQPVLQPPPPTAISQPAS 480

Query: 422 PFQGNAFLTSQPVPVGVVPALQPAFVPAQSYPVANGMPYPAPNVPVVGITPSQMVANVFG 481
           PFQGNAFLTSQPVPVGVVPALQPAFVPAQSYPVANGMPYPAPNVPVVGITPSQMVANVFG
Sbjct: 481 PFQGNAFLTSQPVPVGVVPALQPAFVPAQSYPVANGMPYPAPNVPVVGITPSQMVANVFG 540

Query: 482 TAGHPQAAHPHQSPSLVRQQTFPHYEASSATTSPFFKPPAQHLNGSAAFNGVDDGRLASA 541
           TAGHPQAAHPHQSPSLVRQQTFPHYEASSATTSPFFKPPAQHLNGSAAFNGVDDGRLASA
Sbjct: 541 TAGHPQAAHPHQSPSLVRQQTFPHYEASSATTSPFFKPPAQHLNGSAAFNGVDDGRLASA 600

Query: 542 DRHTEVPTGTCPVDPFEAQWAALENKSKQRTNPSPTNPFSSDLQKTFEIEL 592
           DRHTEVPTGTCPVDPFEAQWAALENKSKQRTNPSPTNPFSSDLQKTFEIEL
Sbjct: 601 DRHTEVPTGTCPVDPFEAQWAALENKSKQRTNPSPTNPFSSDLQKTFEIEL 651


>gi|10863899 numb homolog (Drosophila)-like [Homo sapiens]
          Length = 609

 Score =  597 bits (1539), Expect = e-170
 Identities = 348/625 (55%), Positives = 402/625 (64%), Gaps = 90/625 (14%)

Query: 1   MNKLRQSFRRKKDVYVPEASRPHQWQTDEEGVRTGKCSFPVKYLGHVEVDESRGMHICED 60
           MNKLRQS RR+K  YVPEASRPHQWQ DE+ VR G CSFPV+YLGHVEV+ESRGMH+CED
Sbjct: 42  MNKLRQSLRRRKPAYVPEASRPHQWQADEDAVRKGTCSFPVRYLGHVEVEESRGMHVCED 101

Query: 61  AVKRLKATGKKAVKAVLWVSADGLRVVDEKTKDLIVDQTIEKVSFCAPDRNFDRAFSYIC 120
           AVK+LKA G+K+VK+VLWVSADGLRVVD+KTKDL+VDQTIEKVSFCAPDRN D+AFSYIC
Sbjct: 102 AVKKLKAMGRKSVKSVLWVSADGLRVVDDKTKDLLVDQTIEKVSFCAPDRNLDKAFSYIC 161

Query: 121 RDGTTRRWICHCFMAVKDTGERLSHAVGCAFAACLERKQKREKECGVTATFDASRTTFTR 180
           RDGTTRRWICHCF+A+KD+GERLSHAVGCAFAACLERKQ+REKECGVTA FDASRT+F R
Sbjct: 162 RDGTTRRWICHCFLALKDSGERLSHAVGCAFAACLERKQRREKECGVTAAFDASRTSFAR 221

Query: 181 EGSFRVTTATEQAEREEIMKQMQDAKKAETDKIVVGSSVAPGNTAPSPSSPTSPTSDATT 240
           EGSFR++     AERE       D KKAE        +VAPG   P   SPT  T+    
Sbjct: 222 EGSFRLSGGGRPAERE-----APDKKKAEA---AAAPTVAPGPAQPGHVSPTPATTSPGE 273

Query: 241 SLEMNNP-------HAIPRRHAPIEQLARQGSFRGFPALSQKMSPFKRQLSLRINELPST 293
             E   P        AIPRRHAP+EQL RQGSFRGFPALSQK SPFKRQLSLR+NELPST
Sbjct: 274 KGEAGTPVAAGTTAAAIPRRHAPLEQLVRQGSFRGFPALSQKNSPFKRQLSLRLNELPST 333

Query: 294 MQRKTDFPIKNAVPEVE----GEAESISSLCSQITNAFSTPEDPFSSAPMTKPVTVVAPQ 349
           +QR+TDF +K  VPE+E    G+++SI++LC+QI+++F++   P    P           
Sbjct: 334 LQRRTDFQVKGTVPEMEPPGAGDSDSINALCTQISSSFASAGAPAPGPP----------- 382

Query: 350 SPTFQGTE-WGQSSGAASPGLFQAGHRRTPSEADRWLEEVSKSVRAQQPQ---------- 398
            P   GT  WG+ S       FQ GH+RTPSEA+RWLEEVS+  +AQQ Q          
Sbjct: 383 -PATTGTSAWGEPS-VPPAAAFQPGHKRTPSEAERWLEEVSQVAKAQQQQQQQQQQQQQQ 440

Query: 399 -------ASAAP---LQPVLQPPPPTAISQPASPFQGNAFLTSQPVPVGVVPALQPAFVP 448
                  AS AP   + P LQP P       A+P Q   FL          P +QP FVP
Sbjct: 441 QQQQQQAASVAPVPTMPPALQPFPAPVGPFDAAPAQVAVFLPP--------PHMQPPFVP 492

Query: 449 AQSYPVANGMPY-PAPNVPVVGITPSQMVANVFGTAGHPQAAHPHQSPSLVRQQTFPHYE 507
           A  YP   G+ Y P P VPVVGITPSQMVAN F +A   Q   P  +  L +   FP   
Sbjct: 493 A--YP---GLGYPPMPRVPVVGITPSQMVANAFCSAAQLQ---PQPATLLGKAGAFPPPA 544

Query: 508 ASSATTSPFFKPPAQHLNGSAAFNGVDDGRLASADRHTEVPTGTCPVDPFEAQWAALENK 567
             SA  S     P    NG+                    P     +DPFEAQWAALE K
Sbjct: 545 IPSAPGSQARPRP----NGAPW-------------PPEPAPAPAPELDPFEAQWAALEGK 587

Query: 568 SKQRTNPSPTNPFSSDLQKTFEIEL 592
           +   T   P+NPFS DLQKTFEIEL
Sbjct: 588 A---TVEKPSNPFSGDLQKTFEIEL 609


>gi|7705318 GULP, engulfment adaptor PTB domain containing 1 [Homo
           sapiens]
          Length = 304

 Score = 81.6 bits (200), Expect = 2e-15
 Identities = 61/260 (23%), Positives = 124/260 (47%), Gaps = 34/260 (13%)

Query: 4   LRQSFRRKKDVYVPEASRPHQWQTDEEGVRTGKCSFPVKYLGHVEVDESRGMHICEDAVK 63
           + ++F RKKD           W    E +      +  K+LG  EV++ +G  +  DAV+
Sbjct: 1   MNRAFSRKKD---------KTWMHTPEALSKHFIPYNAKFLGSTEVEQPKGTEVVRDAVR 51

Query: 64  RLK-------ATGKKAVKAVLWVSADGLRVVDEKTKDLIVDQTIEKVSFCAPDRNFDRAF 116
           +LK       + G+K  K  L +S  G+++++ KTK++  +  + ++SFCA D+   R F
Sbjct: 52  KLKFARHIKKSEGQKIPKVELQISIYGVKILEPKTKEVQHNCQLHRISFCADDKTDKRIF 111

Query: 117 SYICRDGTTRRWICHCFMAVKDTGERLSHAVGCAFAACLERKQKREKECGVTATFDASRT 176
           ++IC+D  + + +C+ F + K   E ++  +G AF    +   ++  E G        + 
Sbjct: 112 TFICKDSESNKHLCYVFDSEK-CAEEITLTIGQAF----DLAYRKFLESG-------GKD 159

Query: 177 TFTREGSFRVTTATEQAERE--EIMKQMQDAKKAETDKIVVGSSVAPGNTAPSPSSPTSP 234
             TR+    +    +  E E  E+  ++QD +    +++ +    AP   + +P SP++ 
Sbjct: 160 VETRKQIAGLQKRIQDLETENMELKNKVQDLE----NQLRITQVSAPPAGSMTPKSPSTD 215

Query: 235 TSDATTSLEMNNPHAIPRRH 254
             D      +++  ++P R+
Sbjct: 216 IFDMIPFSPISHQSSMPTRN 235


>gi|132626790 low density lipoprotein receptor adaptor protein 1
           [Homo sapiens]
          Length = 308

 Score = 77.4 bits (189), Expect = 3e-14
 Identities = 63/236 (26%), Positives = 103/236 (43%), Gaps = 32/236 (13%)

Query: 22  PHQWQTDEEGVRTGKCSFPVKYLGHVEVDESRGMHICEDAVKRL----KATGKKAVKAVL 77
           P  W    E +  G   F +KYLG   V++ +G  +   A+KR+    KA+GKK  K  L
Sbjct: 32  PENWTDTRETLLEGML-FSLKYLGMTLVEQPKGEELSAAAIKRIVATAKASGKKLQKVTL 90

Query: 78  WVSADGLRVVDEKTKDLIVDQTIEKVSFCAPDRNFDRAFSYICRDGTTRRWICHCFMAVK 137
            VS  G+ + D  T  LI + +I ++S+C  D+  D+ F+YI +    +   CH F+  K
Sbjct: 91  KVSPRGIILTDNLTNQLIENVSIYRISYCTADKMHDKVFAYIAQSQHNQSLECHAFLCTK 150

Query: 138 -DTGERLSHAVGCAFAACLE--RKQKREKECGVTATFDASRTTFTREGSFRVTTATEQAE 194
               + ++  V  AF    E  +  K EKE          R   ++EG            
Sbjct: 151 RKMAQAVTLTVAQAFKVAFEFWQVSKEEKE---------KRDKASQEGG----------- 190

Query: 195 REEIMKQMQDAKKAETDKIVVGSSVAPGNTAPSPSSPTSPTSDATTSLEMNNPHAI 250
             +++   QD   +    +  G+ +    TA +P S  S  ++ T   E+  P A+
Sbjct: 191 --DVLGARQDCTPSLKSLVATGNLLDLEETAKAPLSTVS--ANTTNMDEVPRPQAL 242


>gi|33350928 disabled homolog 1 [Homo sapiens]
          Length = 555

 Score = 65.1 bits (157), Expect = 2e-10
 Identities = 115/542 (21%), Positives = 198/542 (36%), Gaps = 85/542 (15%)

Query: 30  EGVRTGKCSFPVKYLGHVEVDESRGMHICEDAVKRLKAT-------GKKAVKAVLWVSAD 82
           EGVR     +  K +G  EV  +RG  +C+D++ +LK         G+   K  L +S  
Sbjct: 38  EGVR-----YKAKLIGIDEVSAARGDKLCQDSMMKLKGVVAGARSKGEHKQKIFLTISFG 92

Query: 83  GLRVVDEKTKDLIVDQTIEKVSFCAPDRNFDRAFSYIC-RDGTTRRWICHCFMAVK---- 137
           G+++ DEKT  L     + ++S+ A D    RAF Y+C ++G       H F+A+K    
Sbjct: 93  GIKIFDEKTGALQHHHAVHEISYIAKDITDHRAFGYVCGKEGN------HRFVAIKTAQA 146

Query: 138 ------DTGERLSHAVGCAFAACLERKQKREKECGVTA-----------------TFDAS 174
                 D  +             LE+K +++K+C                      F+A 
Sbjct: 147 AEPVILDLRDLFQLIYELKQREELEKKAQKDKQCEQAVYQTILEEDVEDPVYQYIVFEAG 206

Query: 175 ----RTTFTREGSFRVTTATEQAEREEIMKQMQDAKKAETDKIVVGSSVAPGNTAPSPSS 230
               R   T E  ++V T+ ++    ++ K    +   + +     S+     + P+P++
Sbjct: 207 HEPIRDPETEENIYQVPTSQKKEGVYDVPKSQPVSAVTQLELFGDMSTPPDITSPPTPAT 266

Query: 231 PTS---PTSDATTSLEMNNPHAIPRRHAPIEQLARQGSFRGFPALSQKMSPFKRQLSLRI 287
           P     P+S  T     +   ++P   A +          G+ A+   +  F  Q  L  
Sbjct: 267 PGDAFIPSSSQTLPASADVFSSVPFGTAAVPS--------GYVAMGAVLPSFWGQQPLVQ 318

Query: 288 NELPSTMQRKTDFPIKNAVPEVEGEAESISSLCSQITNAFSTPEDPFSSAPMTKPVTVVA 347
            ++    Q     P+   +P  +  A     L       + T    F  A      TV+ 
Sbjct: 319 QQMVMGAQP----PVAQVMPGAQPIAWGQPGLFPATQQPWPTVAGQFPPAAFMPTQTVMP 374

Query: 348 PQSPTFQGTEWGQSSGAASPGLFQAGHRRTPSEADRWLEEVSKSVRAQQPQASAAPLQPV 407
             +  FQG     +  A  PG   +   R+  + D+  +++ K        A   P+ P 
Sbjct: 375 LPAAMFQGP---LTPLATVPGTSDS--TRSSPQTDKPRQKMGKETFKDFQMAQPPPV-PS 428

Query: 408 LQPPPP--TAISQPASPFQGNAFLTSQPVPVGVVPALQPAFVPAQSY-PVANGMPYPAPN 464
            +P  P  T  S+  S +     +             Q    P  S  P  N  P PAP 
Sbjct: 429 RKPDQPSLTCTSEAFSSYFNKVGVAQDTDDCDDFDISQLNLTPVTSTTPSTNSPPTPAPR 488

Query: 465 VPVVGITPSQMVANVFGTAGHPQA----AHPHQSPSLVRQQTFPHYEASSATTSPFFKPP 520
                 +PS+  A+    A  P          +SPS   +Q  P    +S+ + PF +P 
Sbjct: 489 QS----SPSKSSAS---HASDPTTDDIFEEGFESPSKSEEQEAPDGSQASSNSDPFGEPS 541

Query: 521 AQ 522
            +
Sbjct: 542 GE 543


>gi|50511947 cajalin 2 isoform b [Homo sapiens]
          Length = 510

 Score = 58.9 bits (141), Expect = 1e-08
 Identities = 37/125 (29%), Positives = 59/125 (47%), Gaps = 8/125 (6%)

Query: 19  ASRPHQ-WQTDEEGVRTGKCSFPVKYLGHVEVDESRGMHICEDAVKRLKATGKKAVKA-- 75
           AS P Q WQ   E +    C +   YLG + + E RG    +DA  +++A  +K+ +   
Sbjct: 291 ASTPVQYWQHHPEKLIFQSCDYKAFYLGSMLIKELRGTESTQDACAKMRANCQKSTEQMK 350

Query: 76  -----VLWVSADGLRVVDEKTKDLIVDQTIEKVSFCAPDRNFDRAFSYICRDGTTRRWIC 130
                +L VS  G++ +D   K++I +  I  +S  A D      F+YI +D  +    C
Sbjct: 351 KVPTIILSVSYKGVKFIDATNKNIIAEHEIRNISCAAQDPEDLSTFAYITKDLKSNHHYC 410

Query: 131 HCFMA 135
           H F A
Sbjct: 411 HVFTA 415


>gi|50511945 cajalin 2 isoform a [Homo sapiens]
          Length = 1248

 Score = 58.9 bits (141), Expect = 1e-08
 Identities = 37/125 (29%), Positives = 59/125 (47%), Gaps = 8/125 (6%)

Query: 19   ASRPHQ-WQTDEEGVRTGKCSFPVKYLGHVEVDESRGMHICEDAVKRLKATGKKAVKA-- 75
            AS P Q WQ   E +    C +   YLG + + E RG    +DA  +++A  +K+ +   
Sbjct: 1041 ASTPVQYWQHHPEKLIFQSCDYKAFYLGSMLIKELRGTESTQDACAKMRANCQKSTEQMK 1100

Query: 76   -----VLWVSADGLRVVDEKTKDLIVDQTIEKVSFCAPDRNFDRAFSYICRDGTTRRWIC 130
                 +L VS  G++ +D   K++I +  I  +S  A D      F+YI +D  +    C
Sbjct: 1101 KVPTIILSVSYKGVKFIDATNKNIIAEHEIRNISCAAQDPEDLSTFAYITKDLKSNHHYC 1160

Query: 131  HCFMA 135
            H F A
Sbjct: 1161 HVFTA 1165


>gi|10047134 cajalin 2 isoform c [Homo sapiens]
          Length = 414

 Score = 58.9 bits (141), Expect = 1e-08
 Identities = 37/125 (29%), Positives = 59/125 (47%), Gaps = 8/125 (6%)

Query: 19  ASRPHQ-WQTDEEGVRTGKCSFPVKYLGHVEVDESRGMHICEDAVKRLKATGKKAVKA-- 75
           AS P Q WQ   E +    C +   YLG + + E RG    +DA  +++A  +K+ +   
Sbjct: 207 ASTPVQYWQHHPEKLIFQSCDYKAFYLGSMLIKELRGTESTQDACAKMRANCQKSTEQMK 266

Query: 76  -----VLWVSADGLRVVDEKTKDLIVDQTIEKVSFCAPDRNFDRAFSYICRDGTTRRWIC 130
                +L VS  G++ +D   K++I +  I  +S  A D      F+YI +D  +    C
Sbjct: 267 KVPTIILSVSYKGVKFIDATNKNIIAEHEIRNISCAAQDPEDLSTFAYITKDLKSNHHYC 326

Query: 131 HCFMA 135
           H F A
Sbjct: 327 HVFTA 331


>gi|140161500 ankyrin repeat and sterile alpha motif domain containing
            1 [Homo sapiens]
          Length = 1134

 Score = 56.2 bits (134), Expect = 8e-08
 Identities = 31/115 (26%), Positives = 53/115 (46%), Gaps = 3/115 (2%)

Query: 25   WQTDEEGVRTGKCSFPVKYLGHVEVDESRGMHICEDAVKRLKATG---KKAVKAVLWVSA 81
            WQ   E +    C +   YLG + + + RG    +DA  +++ +    KK    +L ++ 
Sbjct: 928  WQHQPEKLIFESCGYEANYLGSMLIKDLRGTESTQDACAKMRKSTEHMKKIPTIILSITY 987

Query: 82   DGLRVVDEKTKDLIVDQTIEKVSFCAPDRNFDRAFSYICRDGTTRRWICHCFMAV 136
             G++ +D   K++I +  I  +S  A D      F+YI +D  T    CH F  V
Sbjct: 988  KGVKFIDASNKNVIAEHEIRNISCAAQDPEDLCTFAYITKDLQTSHHYCHVFSTV 1042


>gi|19718731 bromodomain-containing protein 4 isoform long [Homo
           sapiens]
          Length = 1362

 Score = 53.1 bits (126), Expect = 7e-07
 Identities = 81/356 (22%), Positives = 128/356 (35%), Gaps = 40/356 (11%)

Query: 189 ATEQAEREEIMKQMQDAKKAETDKIVVGSSVAPGNTAPSPSSPTSPTSDATTS-LEMNNP 247
           A  Q ++ +  K+ +D K+ + +K      V     + +   P   T    +S   ++  
Sbjct: 527 ALSQPQQNKPKKKEKDKKEKKKEKHKRKEEVEENKKSKAKEPPPKKTKKNNSSNSNVSKK 586

Query: 248 HAIPRRHAPIEQLARQGSFRGFPALSQKMSPFKRQLSLRINELPST-------MQRKTDF 300
              P +  P      +   +  P   ++    KRQLSL IN+LP         + +  + 
Sbjct: 587 EPAPMKSKPPPTYESEEEDKCKPMSYEE----KRQLSLDINKLPGEKLGRVVHIIQSREP 642

Query: 301 PIKNAVP-EVEGEAESISSLCSQITNAFSTPEDPFSSAPMTKPVTVVAPQSPT--FQGTE 357
            +KN+ P E+E + E++     +    + T        P  + V V+A  S    F  +E
Sbjct: 643 SLKNSNPDEIEIDFETLKPSTLRELERYVTSCLRKKRKPQAEKVDVIAGSSKMKGFSSSE 702

Query: 358 WGQSSGAASPGLFQAGHRRTPSEADRWL--EEVSKSVRAQQPQASAAPLQPVLQPPPPTA 415
              SS ++S     +     P    +     E  K       Q   AP     QPPPP  
Sbjct: 703 SESSSESSSSDSEDSETEMAPKSKKKGHPGREQKKHHHHHHQQMQQAPAPVPQQPPPPPQ 762

Query: 416 ISQPASPFQGNAFLTSQPVPVGVVPALQPAFVPAQSYPVANGMPYPAPNVPVVGITPSQM 475
              P  P Q       QP P    P++     PA     ++  P+ A  VPV+     Q+
Sbjct: 763 QPPPPPPPQQQ----QQPPPPPPPPSMPQQAAPAMK---SSPPPFIATQVPVL---EPQL 812

Query: 476 VANVFGTAGH--------PQAAHPHQSPSLVRQQTFPHYEASSATTSPFFKPPAQH 523
             +VF   GH        PQ   P   P      T PH    +  +     PPA H
Sbjct: 813 PGSVFDPIGHFTQPILHLPQPELPPHLPQPPEHSTPPHLNQHAVVS-----PPALH 863



 Score = 31.6 bits (70), Expect = 2.1
 Identities = 39/155 (25%), Positives = 50/155 (32%), Gaps = 39/155 (25%)

Query: 359 GQSSGAASPGLFQAGHRRTPSEADRWLEEVSKSVRAQQPQASAAPLQPVLQPPP------ 412
           G+  G    G  + G    P+       + S   + Q PQ +  P+Q    P P      
Sbjct: 178 GRGRGRKETGTAKPGVSTVPNTT-----QASTPPQTQTPQPNPPPVQATPHPFPAVTPDL 232

Query: 413 ----PTAISQPASPFQGNAFLTSQPVPVGVVPALQPAFVPAQSYPVANGMPYPAPNVPVV 468
               P     P  P Q     T  PVP    P   PA  P QS+P            P++
Sbjct: 233 IVQTPVMTVVPPQPLQ-----TPPPVPPQPQPPPAPAPQPVQSHP------------PII 275

Query: 469 GITPSQMVANVFGTAGHPQAAHP------HQSPSL 497
             TP Q V    G         P      H+ PSL
Sbjct: 276 AATP-QPVKTKKGVKRKADTTTPTTIDPIHEPPSL 309



 Score = 30.8 bits (68), Expect = 3.7
 Identities = 54/236 (22%), Positives = 78/236 (33%), Gaps = 27/236 (11%)

Query: 226  PSPSSPTSPTSDATTSLEMNNPHAIPRRHAPIEQLARQGSFRGFPALSQKMSPFKRQLSL 285
            P P  P  P       L+   P   P +  P  Q   Q   R  P   Q M     Q S 
Sbjct: 954  PPPPLPPPPHPSVQQQLQQQPPPPPPPQPQPPPQQQHQPPPR--PVHLQPM-----QFST 1006

Query: 286  RINELPSTMQRKTDFPIKNAVPEVEGEAESISSLCSQITNAFSTPE----DPFSSAPMTK 341
             I + P    ++   P     P     A+       Q+     +P     DP+S+  + +
Sbjct: 1007 HIQQPPPPQGQQPPHPPPGQQPPPPQPAKP-----QQVIQHHHSPRHHKSDPYSTGHLRE 1061

Query: 342  ---PVTVVAPQSPTFQG-TEWGQSSGAASPGLFQAGHRRTPSEADRWLEEVSKSVRAQQP 397
               P+ + +PQ   FQ  T          P   +    R  S        V K  +   P
Sbjct: 1062 APSPLMIHSPQMSQFQSLTHQSPPQQNVQP---KKQELRAASVVQPQPLVVVKEEKIHSP 1118

Query: 398  QASAAPLQPVLQPPPPTAISQPASPFQGNAFLTSQPVPVGVVPALQPAFVPAQSYP 453
               + P  P L+P PP       +P         +PV VG  P ++P   P Q+ P
Sbjct: 1119 IIRSEPFSPSLRPEPPKHPESIKAPVHLPQRPEMKPVDVG-RPVIRP---PEQNAP 1170


>gi|31317301 nitric oxide synthase 1 (neuronal) adaptor protein
           isoform 1 [Homo sapiens]
          Length = 506

 Score = 51.2 bits (121), Expect = 3e-06
 Identities = 63/262 (24%), Positives = 109/262 (41%), Gaps = 43/262 (16%)

Query: 28  DEEGVRTGKCSFPVKYLGHVEVDESRGMHICEDAVKRL----KATGKKAVKAVLWVSADG 83
           +E+  + G C F  KY+G ++V           A++R+    KA   K  K  + VS DG
Sbjct: 22  NEDAFQHGIC-FEAKYVGSLDVPRPNSRVEIVAAMRRIRYEFKAKNIKKKKVSIMVSVDG 80

Query: 84  LRVVDEKTKDLIVDQTIE----------------KVSFCAPDRNFDRAFSYICRDGTTRR 127
           ++V+ +K K L++ Q  E                ++ + + D    + FSYI RDG +  
Sbjct: 81  VKVILKKKKKLLLLQKKEWTWDESKMLVMQDPIYRIFYVSHDSQDLKIFSYIARDGASNI 140

Query: 128 WICHCFMAVKDT-GERLSHAVGCAFAAC----LERKQKR-------EKECGVTATFDASR 175
           + C+ F + K +   R+   VG AF  C    L+  Q+        E E    ++ D  R
Sbjct: 141 FRCNVFKSKKKSQAMRIVRTVGQAFEVCHKLSLQHTQQNADGQEDGESERNSNSSGDPGR 200

Query: 176 TTFTREGSFRVTTAT-EQAEREEIM-----KQMQDAKKAETDKIVVGSSVAPGNTAPSPS 229
                 G+ R +TAT E+ + + +        + +  +  TD   VG      +T    S
Sbjct: 201 QL---TGAERASTATAEETDIDAVEVPLPGNDVLEFSRGVTDLDAVGKE-GGSHTGSKVS 256

Query: 230 SPTSPTSDATTSLEMNNPHAIP 251
            P  P   A+  + + +  + P
Sbjct: 257 HPQEPMLTASPRMLLPSSSSKP 278


>gi|148491082 disabled homolog 2 [Homo sapiens]
          Length = 770

 Score = 50.8 bits (120), Expect = 3e-06
 Identities = 114/513 (22%), Positives = 192/513 (37%), Gaps = 107/513 (20%)

Query: 39  FPVKYLGHVEVDESRGMHICEDAVKRLK---ATGKKAV--KAVLWV--SADGLRVVDEKT 91
           +  K +G  +V ++RG  + +D++ +LK   A G+     K  +WV  S  G++++DEKT
Sbjct: 50  YKAKLIGIDDVPDARGDKMSQDSMMKLKGMAAAGRSQGQHKQRIWVNISLSGIKIIDEKT 109

Query: 92  KDLIVDQTIEKVSFCAPDRNFDRAFSYIC-RDGTTRRWICHCFMAVKDTGERLSHAV--- 147
             +  +  + K+SF A D   +RAF Y+C  +G       H F A+K TG++    V   
Sbjct: 110 GVIEHEHPVNKISFIARDVTDNRAFGYVCGGEGQ------HQFFAIK-TGQQAEPLVVDL 162

Query: 148 GCAFAACLERKQKREKECGVTATFDASRTTFTREGSFRVTTATEQAEREEIMKQMQDAKK 207
              F      K+K E++  +             E S  V   +E      I+    +  K
Sbjct: 163 KDLFQVIYNVKKKEEEKKKI------------EEASKAVENGSEAL---MILDDQTNKLK 207

Query: 208 AETDKIVVGSSVAPGNTAPSPSSPTSPTSDATTSLEMNNPHAIPRRHAPIEQLARQGSFR 267
           +  D++ +   +   +T P  +SPT   S     +++N+           E    Q S R
Sbjct: 208 SGVDQMDLFGDM---STPPDLNSPTE--SKDILLVDLNS-----------EIDTNQNSLR 251

Query: 268 GFPALSQKMSPFKRQLSLRINELPSTMQRKTDFPIKNAVPEVEGEAESISSLCSQITNAF 327
             P L+  ++               ++ R T  P  + +PE         +  S   N F
Sbjct: 252 ENPFLTNGIT-------------SCSLPRPT--PQASFLPE---------NAFSANLNFF 287

Query: 328 STPE-DPFSSAPMTKPVTVVAPQSPTFQGTEWGQSSGAASPGLFQAGHRRTPSEAD---- 382
            TP  DPF   P T+P         + +  +  + + ++S      G    P   D    
Sbjct: 288 PTPNPDPFRDDPFTQPDQSTPSSFDSLKSPDQKKENSSSSSTPLSNG----PLNGDVDYF 343

Query: 383 -RWLEEVSKSVRAQQPQASAAPLQPVLQPPPPTAISQPASPFQGNAF-LTSQPVP-VGVV 439
            +  +++S     Q+ QA   P     Q  P        S  + N F + S P P VG  
Sbjct: 344 GQQFDQISNRTGKQEAQAGPWPFSS-SQTQPAVRTQNGVSEREQNGFSVKSSPNPFVG-- 400

Query: 440 PALQPAFVPAQSYPVANGMPYPAPNVPVVGITPSQMVANVFGTAGHPQAAHPHQSPSLVR 499
                   P +   + NG+     +   V  +P   +A +           P QS    R
Sbjct: 401 -------SPPKGLSIQNGVKQDLES--SVQSSPHDSIAII----------PPPQSTKPGR 441

Query: 500 QQTFPHYEASSATTSPFFKPPAQHLNGSAAFNG 532
            +      A+    S  F PP    +G A+  G
Sbjct: 442 GRRTAKSSANDLLASDIFAPPVSEPSGQASPTG 474


>gi|21327715 transcription elongation regulator 1 isoform 1 [Homo
           sapiens]
          Length = 1098

 Score = 50.1 bits (118), Expect = 6e-06
 Identities = 45/178 (25%), Positives = 71/178 (39%), Gaps = 13/178 (7%)

Query: 305 AVPEVEGEAESISSLCSQITNAFSTPEDPFSSAPMTKPVTVVAPQSPTFQGTEWGQSSGA 364
           A  + + +A+  + + +Q+         P +S+P     T  +  +P+   +    ++  
Sbjct: 233 AQAQAQAQAQVQAQVQAQVQAQAVGASTPTTSSPAPAVSTSTSSSTPSSTTSTTTTATSV 292

Query: 365 ASPGLFQAGHRRTPSEADRWLEEVSKSVRAQQPQASAAPLQPVLQPPPPTAISQPASPFQ 424
           A          +TPS A   +   + +V    P  +A P+Q V QP P T    PA P  
Sbjct: 293 AQTVSTPTTQDQTPSSA---VSVATPTVSVSTPAPTATPVQTVPQPHPQTL--PPAVPH- 346

Query: 425 GNAFLTSQPVPVGVVPALQPAFVPAQSYPVANGMPYPAPNVPVVGITPSQMVANVFGT 482
                 S P P   +PA  P  VP    P+  GMP P P V ++ I     V  V  T
Sbjct: 347 ------SVPQPTTAIPAFPPVMVPPFRVPLP-GMPIPLPGVAMMQIVSCPYVKTVATT 397



 Score = 32.3 bits (72), Expect = 1.3
 Identities = 26/91 (28%), Positives = 37/91 (40%), Gaps = 17/91 (18%)

Query: 394 AQQPQASAAPLQPVLQPPPPTAISQ-----PASPFQGNAF---LTSQPVPVGVVPALQPA 445
           A  P A      P+++PPPP  + +     P  PF    F   +   P P G+ P + P 
Sbjct: 33  APPPNAVMRGPPPLMRPPPPFGMMRGPPPPPRPPFGRPPFDPNMPPMPPPGGIPPPMGPP 92

Query: 446 FV--------PAQSYPVANGMPYPAPNVPVV 468
            +        P  S P   GM +P P +P V
Sbjct: 93  HLQRPPFMPPPMSSMPPPPGMMFP-PGMPPV 122


>gi|149773456 hypothetical protein LOC643314 [Homo sapiens]
          Length = 1427

 Score = 48.9 bits (115), Expect = 1e-05
 Identities = 67/299 (22%), Positives = 110/299 (36%), Gaps = 32/299 (10%)

Query: 220  APGNTAPSPSSPTSPTSDATTSLEMNNPHA-IPRRHAPIEQLARQGSFRGFPALSQKMSP 278
            +P    P+P  PTSP +   T  E  +P A +P    P    A   +    PA      P
Sbjct: 1093 SPAAAVPTPEEPTSPAAAVPTPEEPASPAAAVPTPEEPASPAAAVPTPEE-PAFPAPAVP 1151

Query: 279  FKRQLSLRINELPSTMQRKTDFPIKNAVPEVEGEAESISSLCSQITNAFSTPEDPFSSAP 338
               + +     +P+        P ++A P       + S+  + +      P  P +S P
Sbjct: 1152 TPEESASAAVAVPT--------PEESASPAAAVPTPAESASFAAVVATLEEPTSPAASVP 1203

Query: 339  MTKPVTVVAP----QSPTFQGTEWGQSSGAASPGLFQAGHRRTPSEADRWLEEVSKSVRA 394
               P  +VA      SP        +   + +  +       +P+ A   LEE + S  A
Sbjct: 1204 T--PAAMVATLEEFTSPA-ASVPTSEEPASLAAAVSNPEEPTSPAAAVPTLEEPTSSAAA 1260

Query: 395  Q-QPQASAAPLQPVLQPPPPTAISQPASPFQGNAFLTSQPVPVGVVPALQPAFVPAQSYP 453
               P+  ++P   V  P       +PASP    + L     P   VP  + A +PA S P
Sbjct: 1261 VLTPEELSSPAASVPTP------EEPASPAAAVSNLEEPASPAAAVPTPEVAAIPAASVP 1314

Query: 454  VANGMPYPAPNVPVVGITPSQMVANVFGTAGHPQAAHPHQSPSLVRQQTFPHYEASSAT 512
                     P +P   + P + V+ + G      +AH    P  + ++  P  E +S+T
Sbjct: 1315 TPE-----VPAIPAAAVPPMEEVSPI-GVPFLGVSAHTDSVP--ISEEGTPVLEEASST 1365



 Score = 46.6 bits (109), Expect = 6e-05
 Identities = 62/267 (23%), Positives = 89/267 (33%), Gaps = 24/267 (8%)

Query: 329  TPEDPFSSAPMTKPVTVVAPQSPTFQGTEWGQSSGAASPGLFQAGHRRTPSEADRWLEEV 388
            T ED     P+T   TV AP+ P             ASP    A    TP E        
Sbjct: 965  TEEDGTPEGPVTPATTVHAPEEPDTAAVRVSTPEEPASP----AAAVPTPEEP---TSPA 1017

Query: 389  SKSVRAQQPQASAAPLQPVLQPPPPTAI----SQPASPFQGNAFLTSQPVPVGVVPALQP 444
            +     ++P + AA + P  +P  P A      +P SP            P   VP  + 
Sbjct: 1018 AAVPTPEEPTSPAAAVPPPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEE 1077

Query: 445  AFVPAQSYPVANGMPYPAPNVPVVGITPSQMVANVFGTAGHPQAAHPHQSPSLVRQQTFP 504
               PA + P       PA  VP    TP +  +     A  P    P    + V     P
Sbjct: 1078 PTSPAAAVPTPEEPTSPAAAVP----TPEEPTS---PAAAVPTPEEPASPAAAVPTPEEP 1130

Query: 505  HYEASSATT--SPFFKPPAQHLNGSAAFNGVDDGRLASADRHTEVPTGTCPVDPFEAQWA 562
               A++  T   P F  PA      +A   V           +  P    P     A +A
Sbjct: 1131 ASPAAAVPTPEEPAFPAPAVPTPEESASAAV----AVPTPEESASPAAAVPTPAESASFA 1186

Query: 563  ALENKSKQRTNPSPTNPFSSDLQKTFE 589
            A+    ++ T+P+ + P  + +  T E
Sbjct: 1187 AVVATLEEPTSPAASVPTPAAMVATLE 1213



 Score = 41.6 bits (96), Expect = 0.002
 Identities = 86/360 (23%), Positives = 118/360 (32%), Gaps = 61/360 (16%)

Query: 220  APGNTAPSPSSPTSPTSDATTSLEMNNP-HAIPRRHAPIEQLARQGSFRGFPALSQKMSP 278
            +P    P+P  PTSP +   T  E  +P  A+P    P    A         A+     P
Sbjct: 1002 SPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPPPEEPTSPAA---------AVPTPEEP 1052

Query: 279  FKRQLSLRINELPSTMQRKTDFPIKNAVPEVEGEAESISSLCSQITNAFSTPEDPFSSAP 338
                 ++   E P++       P +   P                  A  TPE+P S A 
Sbjct: 1053 TSPAAAVPTPEEPTSPAAAVPTPEEPTSPAA----------------AVPTPEEPTSPA- 1095

Query: 339  MTKPVTVVAPQSPTFQGTEWGQSSGAASPGLFQAGHRRTPSEADRWLEEVSKSVRAQQPQ 398
                  V  P+ PT            ASP    A    TP       E  S +     P+
Sbjct: 1096 ----AAVPTPEEPTSPAAAVPTPEEPASP----AAAVPTPE------EPASPAAAVPTPE 1141

Query: 399  ASAAPLQPVLQPPPPTAISQPASPFQGNAFLTSQPVPVGVVPALQPAFVPAQSYPVANGM 458
              A P  P +  P  +A +  A P    +   +  VP     A   A V     P +   
Sbjct: 1142 EPAFP-APAVPTPEESASAAVAVPTPEESASPAAAVPTPAESASFAAVVATLEEPTS--- 1197

Query: 459  PYPAPNVPVVGITPSQMVANVFGTAGHPQAAHP--HQSPSLVRQQTFPHYEASSATTSPF 516
              PA +VP    TP+ MVA +      P A+ P   +  SL    + P    S A   P 
Sbjct: 1198 --PAASVP----TPAAMVATLEEFTS-PAASVPTSEEPASLAAAVSNPEEPTSPAAAVPT 1250

Query: 517  FKPPAQHLNGSAAFNGVDDGRLASADRHTEVPTGTCPVDPFEAQWAALENKSKQRTNPSP 576
             + P      S+A   +    L+S      VPT   P  P  A     E  S     P+P
Sbjct: 1251 LEEPT-----SSAAAVLTPEELSSP--AASVPTPEEPASPAAAVSNLEEPASPAAAVPTP 1303


>gi|91208418 transcription elongation regulator 1 isoform 2 [Homo
           sapiens]
          Length = 1077

 Score = 47.8 bits (112), Expect = 3e-05
 Identities = 43/168 (25%), Positives = 69/168 (41%), Gaps = 14/168 (8%)

Query: 305 AVPEVEGEAESISSLCSQITNAFSTPEDPFSSAPMTKPVTVVAPQSPTFQGTEWGQSSGA 364
           A  + + +A+  + + +Q+         P +S+P     T  +  +P+   +    ++  
Sbjct: 233 AQAQAQAQAQVQAQVQAQVQAQAVGASTPTTSSPAPAVSTSTSSSTPSSTTSTTTTATSV 292

Query: 365 ASPGLFQAGHRRTPSEADRWLEEVSKSVRAQQPQASAAPLQPVLQPPPPTAISQPASPFQ 424
           A          +TPS A   +   + +V    P  +A P+Q V QP P T    PA P  
Sbjct: 293 AQTVSTPTTQDQTPSSA---VSVATPTVSVSTPAPTATPVQTVPQPHPQTL--PPAVPH- 346

Query: 425 GNAFLTSQPVPVGVVPALQPAFVPAQSYPVANGMPYPAPNVPVVGITP 472
                 S P P   +PA  P  VP    P+  GMP P P V + G+ P
Sbjct: 347 ------SVPQPTTAIPAFPPVMVPPFRVPLP-GMPIPLPGV-LPGMAP 386



 Score = 32.3 bits (72), Expect = 1.3
 Identities = 26/91 (28%), Positives = 37/91 (40%), Gaps = 17/91 (18%)

Query: 394 AQQPQASAAPLQPVLQPPPPTAISQ-----PASPFQGNAF---LTSQPVPVGVVPALQPA 445
           A  P A      P+++PPPP  + +     P  PF    F   +   P P G+ P + P 
Sbjct: 33  APPPNAVMRGPPPLMRPPPPFGMMRGPPPPPRPPFGRPPFDPNMPPMPPPGGIPPPMGPP 92

Query: 446 FV--------PAQSYPVANGMPYPAPNVPVV 468
            +        P  S P   GM +P P +P V
Sbjct: 93  HLQRPPFMPPPMSSMPPPPGMMFP-PGMPPV 122


>gi|153792074 proline rich 12 [Homo sapiens]
          Length = 2036

 Score = 47.8 bits (112), Expect = 3e-05
 Identities = 63/251 (25%), Positives = 88/251 (35%), Gaps = 24/251 (9%)

Query: 221  PGNTAPS-PSSPTSPTSDATTSLEMNNPHAIPRRHAPIEQLARQGSFRGFPALSQKMSPF 279
            P +  PS P+    P   AT ++    P         +E    +G   G P+  +++   
Sbjct: 1310 PKSVPPSVPARGLQPQPPATPAVPHPPPSGAFGLGGALEAAESEGLGLGCPSPCKRLD-- 1367

Query: 280  KRQLSLRINELPSTMQRKTDFPIKNAVPEVEGEAESISSLCSQITNA-FSTPEDPFSSAP 338
              +L   +  LPS    + D   KN   +     ESISS  S + +   + P+D  +S P
Sbjct: 1368 -EELKRNLETLPSFSSDEEDSVAKNRDLQ-----ESISSAISALDDPPLAGPKD--TSTP 1419

Query: 339  MTKPVTVVA--PQSPTFQGTEWGQSSGAASPGLFQAGHRRTPSEADRWLEEVSKSVRAQQ 396
               P+   A  P  P   G     S+G   P L +     TP  A              Q
Sbjct: 1420 DGPPLAPAAAVPGPPPLPGLPSANSNGTPEPPLLEEKPPPTPPPAP---------TPQPQ 1470

Query: 397  PQASAAPLQPVLQPPPPTAISQPASPFQGNAFLTSQPVPVGVVPALQPAFVPAQSYPVAN 456
            P     P QP L  PPP     P+SP          P      P   PA  P  + P   
Sbjct: 1471 PPPPPPPPQPALPSPPPLVAPTPSSPPPPPLPPPPPPAMPSPPPPPPPAAAPLAAPPEEP 1530

Query: 457  GMPYPA-PNVP 466
              P P  P +P
Sbjct: 1531 AAPSPEDPELP 1541



 Score = 33.5 bits (75), Expect = 0.56
 Identities = 46/158 (29%), Positives = 61/158 (38%), Gaps = 21/158 (13%)

Query: 394 AQQPQASAAPLQPVLQPPPP-TAISQPASP--FQGNAF-LTSQPVPVGVVPALQ--PAFV 447
           ++ P  S  P QP   PPPP  A  Q  SP   QG  + +  +P P G     Q  P   
Sbjct: 470 SKAPSYSGGPPQPPSGPPPPGLATCQSYSPDQLQGQLYGVQGEPYP-GPAAHSQGLPTAS 528

Query: 448 PAQSYPVANGMPYPAPNVPVVGITPSQMVANVFGTAGHPQAAHPHQSPSL------VRQQ 501
           P+ SY   +    PA +    G  PS +     G A       P QSP        V   
Sbjct: 529 PSLSYSTGHS---PALSGHGGGWGPSSLGGG--GEASPSHIIRPLQSPPATGRPPGVGSP 583

Query: 502 TFP-HYEASSATTSPFFKPP--AQHLNGSAAFNGVDDG 536
             P  Y +S   ++PF  PP    +  G+  + G  DG
Sbjct: 584 GAPGKYLSSVLASAPFLAPPGAGSYAAGAGGYKGKGDG 621


>gi|189181724 proteoglycan 4 isoform D [Homo sapiens]
          Length = 1270

 Score = 47.0 bits (110), Expect = 5e-05
 Identities = 90/426 (21%), Positives = 141/426 (33%), Gaps = 50/426 (11%)

Query: 168 TATFDASRTTFTREG-SFRVTTATEQAEREEIMKQMQDAKKAETDKIVVGSSVAPGNTAP 226
           T+T    +TT  +E  S   T+A + A   +++ +     KAET      ++  P  T P
Sbjct: 162 TSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAK--PTPKAET------TTKGPALTTP 213

Query: 227 SPSSPTSPTSDATTSLEMNNPHAI------PRRHAPIE-QLARQGSFRGFPALSQKMSPF 279
              +PT+P   A+T+ +   P  I      P+  AP   + A        P  +++ +P 
Sbjct: 214 KEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPT 273

Query: 280 --KRQLSLRINE-LPSTMQRKTDFPIKNAVPEVEGEAESISSLCSQITNAFSTPEDPFSS 336
             K        E  P+T +     P + A    +  A +     +  T    TP  P   
Sbjct: 274 TPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEP 333

Query: 337 APMTKPVTVVAPQSPTFQGTEWGQSSGAASPGLFQAGHRRTPSEADRWLEEVSKSVRAQQ 396
           AP TK      P+ P     +    +    P         TP E      +       ++
Sbjct: 334 APTTKEPAPTTPKEPAPTAPKKPAPTTPKEPA------PTTPKEPAPTTTKEPSPTTPKE 387

Query: 397 PQASAAPLQPVL--QPPPPTAISQPASPFQGNAFLTSQPVPVGVVPALQPAFVPAQSYPV 454
           P  +     P    +P P T  S P +P + +   T +P P            P +  P 
Sbjct: 388 PAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPT----------TPKEPAPT 437

Query: 455 ANGMPYPAPNVPVVGITPSQMVANVFGTAGHPQAAHPHQSPSLVRQQTFPHYEASSATTS 514
               P P         TP +       T   P    P +      ++T P        T+
Sbjct: 438 TPKKPAPTTPKEPAPTTPKEPAPT---TTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTT 494

Query: 515 PFFKPPAQHLNGSAAFNGVDDGRLASADRHTEVPTGTCPVDPF-EAQWAALENKSKQRTN 573
           P      + L  +             A    E PT T P +P      AA  N  K+   
Sbjct: 495 P------EKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKE--- 545

Query: 574 PSPTNP 579
           P+PT P
Sbjct: 546 PAPTTP 551



 Score = 36.2 bits (82), Expect = 0.087
 Identities = 51/247 (20%), Positives = 81/247 (32%), Gaps = 32/247 (12%)

Query: 221 PGNTAPSPSSPTSPTSDATTSLEMNNPHAIPRRHAPIEQLARQGSFRGFPALSQKMSPFK 280
           P  T P   +PT+P   A T+         P+  AP        +    PA +    P  
Sbjct: 546 PAPTTPKEPAPTTPKEPAPTT---------PKETAPTTPKGTAPTTLKEPAPTTPKKPAP 596

Query: 281 RQLSLRINELPSTMQRKTDFPIKNAVPEV-EGEAESISSLCSQITNAFSTPEDPFSSAPM 339
           ++L+      P+T +  T        P   +G A +     +  T     P  P  +AP 
Sbjct: 597 KELA------PTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPT 650

Query: 340 T-KPVTVVAPQSPTFQGTEWGQSSGAASPGLFQAGHRRTPSEADRWLEEVSKSVRAQQPQ 398
           T K      P+ P  +      + G  S        +  P+          K      P+
Sbjct: 651 TLKEPAPTTPKKPAPKELAPTTTKGPTS----TTSDKPAPTTPKETAPTTPKEPAPTTPK 706

Query: 399 ASAAPLQPVLQPPPPTAISQPA----------SPFQGNAFLTSQPVPVGVVPALQPAFVP 448
              AP  P   PP  + +S P           SP +    L+++P P  +  + +   VP
Sbjct: 707 -KPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEPGVP 765

Query: 449 AQSYPVA 455
               P A
Sbjct: 766 TTKTPAA 772


>gi|189181722 proteoglycan 4 isoform C [Homo sapiens]
          Length = 1311

 Score = 47.0 bits (110), Expect = 5e-05
 Identities = 90/426 (21%), Positives = 141/426 (33%), Gaps = 50/426 (11%)

Query: 168 TATFDASRTTFTREG-SFRVTTATEQAEREEIMKQMQDAKKAETDKIVVGSSVAPGNTAP 226
           T+T    +TT  +E  S   T+A + A   +++ +     KAET      ++  P  T P
Sbjct: 203 TSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAK--PTPKAET------TTKGPALTTP 254

Query: 227 SPSSPTSPTSDATTSLEMNNPHAI------PRRHAPIE-QLARQGSFRGFPALSQKMSPF 279
              +PT+P   A+T+ +   P  I      P+  AP   + A        P  +++ +P 
Sbjct: 255 KEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPT 314

Query: 280 --KRQLSLRINE-LPSTMQRKTDFPIKNAVPEVEGEAESISSLCSQITNAFSTPEDPFSS 336
             K        E  P+T +     P + A    +  A +     +  T    TP  P   
Sbjct: 315 TPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEP 374

Query: 337 APMTKPVTVVAPQSPTFQGTEWGQSSGAASPGLFQAGHRRTPSEADRWLEEVSKSVRAQQ 396
           AP TK      P+ P     +    +    P         TP E      +       ++
Sbjct: 375 APTTKEPAPTTPKEPAPTAPKKPAPTTPKEPA------PTTPKEPAPTTTKEPSPTTPKE 428

Query: 397 PQASAAPLQPVL--QPPPPTAISQPASPFQGNAFLTSQPVPVGVVPALQPAFVPAQSYPV 454
           P  +     P    +P P T  S P +P + +   T +P P            P +  P 
Sbjct: 429 PAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPT----------TPKEPAPT 478

Query: 455 ANGMPYPAPNVPVVGITPSQMVANVFGTAGHPQAAHPHQSPSLVRQQTFPHYEASSATTS 514
               P P         TP +       T   P    P +      ++T P        T+
Sbjct: 479 TPKKPAPTTPKEPAPTTPKEPAPT---TTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTT 535

Query: 515 PFFKPPAQHLNGSAAFNGVDDGRLASADRHTEVPTGTCPVDPF-EAQWAALENKSKQRTN 573
           P      + L  +             A    E PT T P +P      AA  N  K+   
Sbjct: 536 P------EKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKE--- 586

Query: 574 PSPTNP 579
           P+PT P
Sbjct: 587 PAPTTP 592



 Score = 36.2 bits (82), Expect = 0.087
 Identities = 51/247 (20%), Positives = 81/247 (32%), Gaps = 32/247 (12%)

Query: 221 PGNTAPSPSSPTSPTSDATTSLEMNNPHAIPRRHAPIEQLARQGSFRGFPALSQKMSPFK 280
           P  T P   +PT+P   A T+         P+  AP        +    PA +    P  
Sbjct: 587 PAPTTPKEPAPTTPKEPAPTT---------PKETAPTTPKGTAPTTLKEPAPTTPKKPAP 637

Query: 281 RQLSLRINELPSTMQRKTDFPIKNAVPEV-EGEAESISSLCSQITNAFSTPEDPFSSAPM 339
           ++L+      P+T +  T        P   +G A +     +  T     P  P  +AP 
Sbjct: 638 KELA------PTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPT 691

Query: 340 T-KPVTVVAPQSPTFQGTEWGQSSGAASPGLFQAGHRRTPSEADRWLEEVSKSVRAQQPQ 398
           T K      P+ P  +      + G  S        +  P+          K      P+
Sbjct: 692 TLKEPAPTTPKKPAPKELAPTTTKGPTS----TTSDKPAPTTPKETAPTTPKEPAPTTPK 747

Query: 399 ASAAPLQPVLQPPPPTAISQPA----------SPFQGNAFLTSQPVPVGVVPALQPAFVP 448
              AP  P   PP  + +S P           SP +    L+++P P  +  + +   VP
Sbjct: 748 -KPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEPGVP 806

Query: 449 AQSYPVA 455
               P A
Sbjct: 807 TTKTPAA 813


>gi|189181720 proteoglycan 4 isoform B [Homo sapiens]
          Length = 1363

 Score = 47.0 bits (110), Expect = 5e-05
 Identities = 90/426 (21%), Positives = 141/426 (33%), Gaps = 50/426 (11%)

Query: 168 TATFDASRTTFTREG-SFRVTTATEQAEREEIMKQMQDAKKAETDKIVVGSSVAPGNTAP 226
           T+T    +TT  +E  S   T+A + A   +++ +     KAET      ++  P  T P
Sbjct: 255 TSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAK--PTPKAET------TTKGPALTTP 306

Query: 227 SPSSPTSPTSDATTSLEMNNPHAI------PRRHAPIE-QLARQGSFRGFPALSQKMSPF 279
              +PT+P   A+T+ +   P  I      P+  AP   + A        P  +++ +P 
Sbjct: 307 KEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPT 366

Query: 280 --KRQLSLRINE-LPSTMQRKTDFPIKNAVPEVEGEAESISSLCSQITNAFSTPEDPFSS 336
             K        E  P+T +     P + A    +  A +     +  T    TP  P   
Sbjct: 367 TPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEP 426

Query: 337 APMTKPVTVVAPQSPTFQGTEWGQSSGAASPGLFQAGHRRTPSEADRWLEEVSKSVRAQQ 396
           AP TK      P+ P     +    +    P         TP E      +       ++
Sbjct: 427 APTTKEPAPTTPKEPAPTAPKKPAPTTPKEPA------PTTPKEPAPTTTKEPSPTTPKE 480

Query: 397 PQASAAPLQPVL--QPPPPTAISQPASPFQGNAFLTSQPVPVGVVPALQPAFVPAQSYPV 454
           P  +     P    +P P T  S P +P + +   T +P P            P +  P 
Sbjct: 481 PAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPT----------TPKEPAPT 530

Query: 455 ANGMPYPAPNVPVVGITPSQMVANVFGTAGHPQAAHPHQSPSLVRQQTFPHYEASSATTS 514
               P P         TP +       T   P    P +      ++T P        T+
Sbjct: 531 TPKKPAPTTPKEPAPTTPKEPAPT---TTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTT 587

Query: 515 PFFKPPAQHLNGSAAFNGVDDGRLASADRHTEVPTGTCPVDPF-EAQWAALENKSKQRTN 573
           P      + L  +             A    E PT T P +P      AA  N  K+   
Sbjct: 588 P------EKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKE--- 638

Query: 574 PSPTNP 579
           P+PT P
Sbjct: 639 PAPTTP 644



 Score = 36.2 bits (82), Expect = 0.087
 Identities = 51/247 (20%), Positives = 81/247 (32%), Gaps = 32/247 (12%)

Query: 221 PGNTAPSPSSPTSPTSDATTSLEMNNPHAIPRRHAPIEQLARQGSFRGFPALSQKMSPFK 280
           P  T P   +PT+P   A T+         P+  AP        +    PA +    P  
Sbjct: 639 PAPTTPKEPAPTTPKEPAPTT---------PKETAPTTPKGTAPTTLKEPAPTTPKKPAP 689

Query: 281 RQLSLRINELPSTMQRKTDFPIKNAVPEV-EGEAESISSLCSQITNAFSTPEDPFSSAPM 339
           ++L+      P+T +  T        P   +G A +     +  T     P  P  +AP 
Sbjct: 690 KELA------PTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPT 743

Query: 340 T-KPVTVVAPQSPTFQGTEWGQSSGAASPGLFQAGHRRTPSEADRWLEEVSKSVRAQQPQ 398
           T K      P+ P  +      + G  S        +  P+          K      P+
Sbjct: 744 TLKEPAPTTPKKPAPKELAPTTTKGPTS----TTSDKPAPTTPKETAPTTPKEPAPTTPK 799

Query: 399 ASAAPLQPVLQPPPPTAISQPA----------SPFQGNAFLTSQPVPVGVVPALQPAFVP 448
              AP  P   PP  + +S P           SP +    L+++P P  +  + +   VP
Sbjct: 800 -KPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEPGVP 858

Query: 449 AQSYPVA 455
               P A
Sbjct: 859 TTKTPAA 865


>gi|67190163 proteoglycan 4 isoform A [Homo sapiens]
          Length = 1404

 Score = 47.0 bits (110), Expect = 5e-05
 Identities = 90/426 (21%), Positives = 141/426 (33%), Gaps = 50/426 (11%)

Query: 168 TATFDASRTTFTREG-SFRVTTATEQAEREEIMKQMQDAKKAETDKIVVGSSVAPGNTAP 226
           T+T    +TT  +E  S   T+A + A   +++ +     KAET      ++  P  T P
Sbjct: 296 TSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAK--PTPKAET------TTKGPALTTP 347

Query: 227 SPSSPTSPTSDATTSLEMNNPHAI------PRRHAPIE-QLARQGSFRGFPALSQKMSPF 279
              +PT+P   A+T+ +   P  I      P+  AP   + A        P  +++ +P 
Sbjct: 348 KEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPT 407

Query: 280 --KRQLSLRINE-LPSTMQRKTDFPIKNAVPEVEGEAESISSLCSQITNAFSTPEDPFSS 336
             K        E  P+T +     P + A    +  A +     +  T    TP  P   
Sbjct: 408 TPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEP 467

Query: 337 APMTKPVTVVAPQSPTFQGTEWGQSSGAASPGLFQAGHRRTPSEADRWLEEVSKSVRAQQ 396
           AP TK      P+ P     +    +    P         TP E      +       ++
Sbjct: 468 APTTKEPAPTTPKEPAPTAPKKPAPTTPKEPA------PTTPKEPAPTTTKEPSPTTPKE 521

Query: 397 PQASAAPLQPVL--QPPPPTAISQPASPFQGNAFLTSQPVPVGVVPALQPAFVPAQSYPV 454
           P  +     P    +P P T  S P +P + +   T +P P            P +  P 
Sbjct: 522 PAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPT----------TPKEPAPT 571

Query: 455 ANGMPYPAPNVPVVGITPSQMVANVFGTAGHPQAAHPHQSPSLVRQQTFPHYEASSATTS 514
               P P         TP +       T   P    P +      ++T P        T+
Sbjct: 572 TPKKPAPTTPKEPAPTTPKEPAPT---TTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTT 628

Query: 515 PFFKPPAQHLNGSAAFNGVDDGRLASADRHTEVPTGTCPVDPF-EAQWAALENKSKQRTN 573
           P      + L  +             A    E PT T P +P      AA  N  K+   
Sbjct: 629 P------EKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKE--- 679

Query: 574 PSPTNP 579
           P+PT P
Sbjct: 680 PAPTTP 685



 Score = 36.2 bits (82), Expect = 0.087
 Identities = 51/247 (20%), Positives = 81/247 (32%), Gaps = 32/247 (12%)

Query: 221 PGNTAPSPSSPTSPTSDATTSLEMNNPHAIPRRHAPIEQLARQGSFRGFPALSQKMSPFK 280
           P  T P   +PT+P   A T+         P+  AP        +    PA +    P  
Sbjct: 680 PAPTTPKEPAPTTPKEPAPTT---------PKETAPTTPKGTAPTTLKEPAPTTPKKPAP 730

Query: 281 RQLSLRINELPSTMQRKTDFPIKNAVPEV-EGEAESISSLCSQITNAFSTPEDPFSSAPM 339
           ++L+      P+T +  T        P   +G A +     +  T     P  P  +AP 
Sbjct: 731 KELA------PTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPT 784

Query: 340 T-KPVTVVAPQSPTFQGTEWGQSSGAASPGLFQAGHRRTPSEADRWLEEVSKSVRAQQPQ 398
           T K      P+ P  +      + G  S        +  P+          K      P+
Sbjct: 785 TLKEPAPTTPKKPAPKELAPTTTKGPTS----TTSDKPAPTTPKETAPTTPKEPAPTTPK 840

Query: 399 ASAAPLQPVLQPPPPTAISQPA----------SPFQGNAFLTSQPVPVGVVPALQPAFVP 448
              AP  P   PP  + +S P           SP +    L+++P P  +  + +   VP
Sbjct: 841 -KPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEPGVP 899

Query: 449 AQSYPVA 455
               P A
Sbjct: 900 TTKTPAA 906


>gi|146219843 Snf2-related CBP activator protein [Homo sapiens]
          Length = 3230

 Score = 46.6 bits (109), Expect = 6e-05
 Identities = 93/387 (24%), Positives = 144/387 (37%), Gaps = 74/387 (19%)

Query: 224  TAPSPSS-PTSPTSDATTSLEMNNPHAIPRRHAPIEQLARQGSFRGFPALSQK-MSPFKR 281
            T P+P+S P +    A  ++  + P  +     P+  +       G P+L+    SP   
Sbjct: 1446 TLPAPASAPLTIPISAPLTVSASGPALLTSVTPPLAPVVPAAP--GPPSLAPSGASPSAS 1503

Query: 282  QLSLRINELPSTMQRKTD------FPIKNAVPEVEGEAESISSLCSQITNAFSTPEDPFS 335
             L+L +   PS    +T        P  + VP   G   +++  CS +    S    PF 
Sbjct: 1504 ALTLGLATAPSLSSSQTPGHPLLLAPTSSHVP---GLNSTVAPACSPVLVPASALASPFP 1560

Query: 336  SAPMTKP--VTVVAPQSPTFQGTEWGQSSGAASPGLFQAGHRRTPSEADRWLEEVSKSVR 393
            SAP   P   +++AP S          S   A+P          P  A +       ++ 
Sbjct: 1561 SAPNPAPAQASLLAPAS--------SASQALATP--------LAPMAAPQ------TAIL 1598

Query: 394  AQQPQASAAPLQPVLQPPP-----------PTAISQPASPFQGNAFLTSQPVPVG---VV 439
            A  P    APL PVL P P           P  +  P+S   G +  ++ PVP     + 
Sbjct: 1599 APSPAPPLAPL-PVLAPSPGAAPVLASSQTPVPVMAPSST-PGTSLASASPVPAPTPVLA 1656

Query: 440  PALQPAFVPAQSYPVANGMPYPAPNVPVV----------GITPSQMVANVFGTAGHPQAA 489
            P+     +PA   PV + +P PA    +           G +PSQ ++   GT G+PQ  
Sbjct: 1657 PSSTQTMLPA---PVPSPLPSPASTQTLALAPALAPTLGGSSPSQTLS--LGT-GNPQGP 1710

Query: 490  HPHQSPSLVRQQTFPHYEASSATTSPFFKPPAQHLNGSAAFNGVDDGRLASADRHTEVPT 549
             P Q+ SL    +     A + + +P   PP   L  +   +      LA A      P 
Sbjct: 1711 FPTQTLSLTPASSLVPTPAQTLSLAP--GPP---LGPTQTLSLAPAPPLAPASPVGPAPA 1765

Query: 550  GTCPVDPFEAQWAALENKSKQRTNPSP 576
             T  + P  +  + L   S Q    SP
Sbjct: 1766 HTLTLAPASSSASLLAPASVQTLTLSP 1792


>gi|91208420 bassoon protein [Homo sapiens]
          Length = 3926

 Score = 45.4 bits (106), Expect = 1e-04
 Identities = 45/180 (25%), Positives = 66/180 (36%), Gaps = 11/180 (6%)

Query: 397  PQASAAPLQPVLQPPPPTAISQPASPFQGNAFLTSQPVPVGVVPALQPAFVPAQSYPVAN 456
            P    A  QP  QPP P   +    P Q        P   G      PAF P  SYP   
Sbjct: 3045 PSGPTAFQQPRFQPPAPQYSAGSGGPTQNGFPAHQAPTYPGPSTYPAPAFPPGASYPAEP 3104

Query: 457  GMPYP---APNVPVVGITPSQMV-ANVFGTAGHPQA--AHPHQSPSLVRQQTFP-HYEAS 509
            G+P      P     G TP     + +F      +A    P Q+     +Q  P +YE  
Sbjct: 3105 GLPNQQAFRPTGHYAGQTPMPTTQSTLFPVPADSRAPLQKPRQTSLADLEQKVPTNYEVI 3164

Query: 510  SATTSPFFKPPAQ-HLNGSAAFNGVDDGRLASADR---HTEVPTGTCPVDPFEAQWAALE 565
            ++   P    P++   +G A  +G + G++    R      V     P  P ++ + +LE
Sbjct: 3165 ASPVVPMSSAPSETSYSGPAVSSGYEQGKVPEVPRAGDRGSVSQSPAPTYPSDSHYTSLE 3224



 Score = 30.4 bits (67), Expect = 4.8
 Identities = 80/331 (24%), Positives = 117/331 (35%), Gaps = 59/331 (17%)

Query: 180  REGSFRVTTATEQAEREEIMKQMQDAKKAETDKIVV-GSSVAPGNTAPSPSSPTSPTSDA 238
            R+ S R     E  ++E   KQ  +A+ A  D +   G  + PG    SP+   +P S +
Sbjct: 1271 RQASSRDLAFAEDKKKE---KQFLNAESAYMDPMKQNGGPLTPGT---SPTQLAAPVSFS 1324

Query: 239  T-TSLEMNNPHAIPRRHAPIEQLARQGSFRGFPALSQKMSPFK--RQLSLRINELPSTMQ 295
            T TS + +    IP     + Q   + +       S   SP    +++ +  ++ P T  
Sbjct: 1325 TPTSSDSSGGRVIP--DVRVTQHFAKETQDPLKLHSSPASPSSASKEIGMPFSQGPGTPA 1382

Query: 296  RKTDFPIKNAVPEVEGEAESISSLCSQITNAFSTPEDPFSSAPMTKPV---TVVAPQSPT 352
                 P    +P   G     S   S+ + + S+    +  +P T      T   PQ+P 
Sbjct: 1383 TTAVAPCPAGLPR--GYMTPASPAGSERSPSPSSTAHSYGHSPTTANYGSQTEDLPQAP- 1439

Query: 353  FQGTEWGQSSGAASPGLFQAGHRRTPSEADRWLEEVSKSVRAQQPQASAAP-LQPVLQPP 411
                     SG A+ G      R  P  A        +  RA    AS++P L P     
Sbjct: 1440 ---------SGLAAAG---RAAREKPLSASDGEGGTPQPSRAYSYFASSSPPLSPSSPSE 1487

Query: 412  PPTAISQPASPFQGNAFLTSQPVPVGVVPALQPAFVPAQSYPVANGMPYPAPNVPVVGIT 471
             PT       P     F T  P P            PA   P + G P           T
Sbjct: 1488 SPTFSPGKMGPRATAEFSTQTPSPA-----------PASDMPRSPGAP-----------T 1525

Query: 472  PSQMVANVFGTAGHPQAAHPHQSPSLVRQQT 502
            PS MVA   GT    Q  H   +P LV Q++
Sbjct: 1526 PSPMVAQ--GT----QTPHRPSTPRLVWQES 1550


>gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo
           sapiens]
          Length = 855

 Score = 45.1 bits (105), Expect = 2e-04
 Identities = 75/309 (24%), Positives = 108/309 (34%), Gaps = 43/309 (13%)

Query: 215 VGSSVAPGNTAPSPSSPTSPTSDATTSLEMNNPHAIPRRHAPIEQLARQG-SFRGFPALS 273
           V S+     T PSP++   P++     L+     ++     P+   AR G S RG P   
Sbjct: 209 VSSASEHSTTEPSPAARRRPSAGG--GLQRPASRSLSSSATPLSSPARSGPSARGTPRAP 266

Query: 274 QKMSPFKRQLSLRINELPSTMQRK---------TDFPIKNAVPEVEGEAESISSL----- 319
              S  K +    +     T  RK         +  P+    P    ++++  +L     
Sbjct: 267 AHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAALQSQAPPTLPATPH 326

Query: 320 CSQITNAFSTP---EDPFSSAPMTKPVTVVAPQSPTFQGTEWGQSSGAASPGLFQAGHRR 376
            S +T   +TP     P  SAP +       P +P  Q T     +   SP L QA H  
Sbjct: 327 SSSLTCQLATPLPLAPPSPSAPPSLQTLPSPPATPPSQAT-----TSLGSPTL-QATHSF 380

Query: 377 TPSEADRWLEEVSKSVRAQQPQASAAPLQPVLQPPP---------PTAISQPASPFQGNA 427
            PS            +    PQA  A   P LQ PP         P A   P +P     
Sbjct: 381 LPSPP-------LSPLATPPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNALAV 433

Query: 428 FLTSQPVPVGVVPALQPAFVPAQSYPVANGMPYPAPNVPVVGITPSQMVANVFGTAG-HP 486
            L   P      P +Q  F P  S PV+     P+   P +   P Q+  +   +    P
Sbjct: 434 HLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSP 493

Query: 487 QAAHPHQSP 495
            A  P Q+P
Sbjct: 494 SATPPPQAP 502



 Score = 34.3 bits (77), Expect = 0.33
 Identities = 78/329 (23%), Positives = 114/329 (34%), Gaps = 56/329 (17%)

Query: 217 SSVAPGNTAPSPSSPTSPTSDATTSLEMNNPHAIPRRHAPIEQLARQGSFRGFPALSQKM 276
           S  AP +    PS P +P S ATTSL            +P  Q     SF   P LS   
Sbjct: 344 SPSAPPSLQTLPSPPATPPSQATTSLG-----------SPTLQATH--SFLPSPPLSPLA 390

Query: 277 SPFKRQL-SLRINELPSTMQRKTDFPIKNAVPEVEGEAESISSLCSQITNA-FSTPEDPF 334
           +P  +   +L +  L +        P+    P      ++ ++L   +  A FS P  P 
Sbjct: 391 TPPPQAPPALALPPLQAPPSPPASPPLS---PLATPSPQAPNALAVHLLQAPFSPPPSPP 447

Query: 335 SSAPMTKPVTVVAPQSPTFQGTEWGQSSGAASPGLFQAGHRRTPSEADRWLEEVSKSVRA 394
             AP + P +   P SP+         S AA P                   +V  S  A
Sbjct: 448 VQAPFSPPAS--PPVSPSATPPSQAPPSLAAPP------------------LQVPPSPPA 487

Query: 395 QQPQASAAPLQPVLQPPPPTAISQPASPFQGNAFLTSQPVPVGVVPALQPAFVPAQSYPV 454
             P + +A        PPP A    A+P    A    Q  P    P LQ    P  S+P 
Sbjct: 488 SPPMSPSAT-------PPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFP- 539

Query: 455 ANGMPY-PAPNVPVVGI-TPSQMVANVFGTAGHPQAAHPHQSPSLVRQQTFPHYEASSAT 512
               P+ P+ ++P+  + TP      V           P  SP+L   +  P     ++ 
Sbjct: 540 -GQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSV 598

Query: 513 TSPFF-------KPPAQHLNGSAAFNGVD 534
           + P          PP    + S+  +G D
Sbjct: 599 SGPRLTLALAPGPPPPPSRSPSSTLSGPD 627


>gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo
           sapiens]
          Length = 816

 Score = 45.1 bits (105), Expect = 2e-04
 Identities = 73/292 (25%), Positives = 101/292 (34%), Gaps = 39/292 (13%)

Query: 215 VGSSVAPGNTAPSPSSPTSPTSDATTSLEMNNPHAIPRRHAPIEQLARQG-SFRGFPALS 273
           V S+     T PSP++   P++     L+     ++     P+   AR G S RG P   
Sbjct: 200 VSSASEHSTTEPSPAARRRPSAGG--GLQRPASRSLSSSATPLSSPARSGPSARGTPRAP 257

Query: 274 QKMSPFKRQLSLRINELPSTMQRKTDFPIKNAVPEVEGEAESISSLCSQITNAFSTPEDP 333
              S  K +       L +    +   P K+A P       ++  L S      S    P
Sbjct: 258 AHPSQPKPK------GLQALRPPQVTPPRKDAAP-------ALGPLSSSPLATPSPSAPP 304

Query: 334 FSSAPMTKPVTVVAPQSPTFQGTEWGQSSGAASPGLFQAGHRRTPSEADRWLEEVSKSVR 393
             SAP +       P +P  Q T     +   SP L QA H   PS            + 
Sbjct: 305 SPSAPPSLQTLPSPPATPPSQAT-----TSLGSPTL-QATHSFLPSPP-------LSPLA 351

Query: 394 AQQPQASAAPLQPVLQPPP---------PTAISQPASPFQGNAFLTSQPVPVGVVPALQP 444
              PQA  A   P LQ PP         P A   P +P      L   P      P +Q 
Sbjct: 352 TPPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQA 411

Query: 445 AFVPAQSYPVANGMPYPAPNVPVVGITPSQMVANVFGTAG-HPQAAHPHQSP 495
            F P  S PV+     P+   P +   P Q+  +   +    P A  P Q+P
Sbjct: 412 PFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAP 463



 Score = 34.3 bits (77), Expect = 0.33
 Identities = 78/329 (23%), Positives = 114/329 (34%), Gaps = 56/329 (17%)

Query: 217 SSVAPGNTAPSPSSPTSPTSDATTSLEMNNPHAIPRRHAPIEQLARQGSFRGFPALSQKM 276
           S  AP +    PS P +P S ATTSL            +P  Q     SF   P LS   
Sbjct: 305 SPSAPPSLQTLPSPPATPPSQATTSLG-----------SPTLQATH--SFLPSPPLSPLA 351

Query: 277 SPFKRQL-SLRINELPSTMQRKTDFPIKNAVPEVEGEAESISSLCSQITNA-FSTPEDPF 334
           +P  +   +L +  L +        P+    P      ++ ++L   +  A FS P  P 
Sbjct: 352 TPPPQAPPALALPPLQAPPSPPASPPLS---PLATPSPQAPNALAVHLLQAPFSPPPSPP 408

Query: 335 SSAPMTKPVTVVAPQSPTFQGTEWGQSSGAASPGLFQAGHRRTPSEADRWLEEVSKSVRA 394
             AP + P +   P SP+         S AA P                   +V  S  A
Sbjct: 409 VQAPFSPPAS--PPVSPSATPPSQAPPSLAAPP------------------LQVPPSPPA 448

Query: 395 QQPQASAAPLQPVLQPPPPTAISQPASPFQGNAFLTSQPVPVGVVPALQPAFVPAQSYPV 454
             P + +A        PPP A    A+P    A    Q  P    P LQ    P  S+P 
Sbjct: 449 SPPMSPSAT-------PPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFP- 500

Query: 455 ANGMPY-PAPNVPVVGI-TPSQMVANVFGTAGHPQAAHPHQSPSLVRQQTFPHYEASSAT 512
               P+ P+ ++P+  + TP      V           P  SP+L   +  P     ++ 
Sbjct: 501 -GQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSV 559

Query: 513 TSPFF-------KPPAQHLNGSAAFNGVD 534
           + P          PP    + S+  +G D
Sbjct: 560 SGPRLTLALAPGPPPPPSRSPSSTLSGPD 588


>gi|7662236 TSC22 domain family, member 2 [Homo sapiens]
          Length = 780

 Score = 44.3 bits (103), Expect = 3e-04
 Identities = 56/212 (26%), Positives = 76/212 (35%), Gaps = 53/212 (25%)

Query: 311 GEAESISSLCSQITNAFSTPEDPFSSAPMTKPVT--VVAPQSPTFQGTEWGQSSGAASPG 368
           G  ++ SS+ +Q+  A S P +  + AP T P     VAP  PT  G       G   P 
Sbjct: 414 GTGQNASSVGAQLMGASSQPSE--AMAPRTGPAQGGQVAPCQPT--GVPPATVGGVVQPC 469

Query: 369 LFQAGHRRTPSEADRWLEEVSKSVRAQQPQASAAPLQPVLQPPPPTAISQPASPFQGNAF 428
           L  AG                    A QPQ+          PPP    S P S   G   
Sbjct: 470 LGPAG--------------------AGQPQSV---------PPPQMGGSGPLSAVPGG-- 498

Query: 429 LTSQPVPVGVVPALQ--PAFVPAQSYPVANGMPYPAPNVP--------VVGITPSQMVAN 478
                 P  VVP +   PA VPA S P  +      PNVP        +   TP    ++
Sbjct: 499 ------PHAVVPGVPNVPAAVPAPSVPSVSTTSVTMPNVPAPLAQSQQLSSHTPVSRSSS 552

Query: 479 VFGTAGHPQAAHPHQSPSLVRQQTFPHYEASS 510
           +    G P A   H +P+ + Q     ++  +
Sbjct: 553 IIQHVGLPLAPGTHSAPTSLPQSDLSQFQTQT 584


>gi|222418647 mucin 7, secreted precursor [Homo sapiens]
          Length = 377

 Score = 43.9 bits (102), Expect = 4e-04
 Identities = 69/306 (22%), Positives = 104/306 (33%), Gaps = 49/306 (16%)

Query: 228 PSSPTSPTSDATTSLEMNNPHAIPRRHAPIEQLARQGSFRG-------------FPALSQ 274
           P  P SP          NNP   P  H P +   +  S                FP+ S 
Sbjct: 72  PKLPPSP----------NNPPKFPNPHQPPKHPDKNSSVVNPTLVATTQIPSVTFPSAST 121

Query: 275 KMSPFKRQLSLRINELPSTMQRKTDFPIKNAVPEVEGEAESISSLCSQITNAFSTPEDPF 334
           K++       L  N    + +   +     A            +  +  T + +TP  P 
Sbjct: 122 KITTLPNVTFLPQNATTISSRENVNTSSSVATLAPVNSPAPQDTTAAPPTPSATTPAPPS 181

Query: 335 SSAPMTKPVTVVAPQSPTFQGTEWGQSSGA-----ASPGLFQAGHRRTPSEA---DRWLE 386
           SSAP   P T  AP +P+   T+   SS A     A+P    A     PS +   +    
Sbjct: 182 SSAP---PETTAAPPTPSAT-TQAPPSSSAPPETTAAPPTPPATTPAPPSSSAPPETTAA 237

Query: 387 EVSKSVRAQQPQASAAPLQPVLQPPPPTAIS-QPASPFQGNAFLTSQPVPVGVVPALQPA 445
             + S     P +S+AP +    PP P+A +  P+S         + P P    PA    
Sbjct: 238 PPTPSATTPAPLSSSAPPETTAVPPTPSATTLDPSSASAPPETTAAPPTPSATTPA---- 293

Query: 446 FVPAQSYPVANGMPYPAPNVPVVGITPSQMVANVFGTAGHPQAAHPHQSPSLVRQQTFPH 505
                  P ++  P      P+   TP+     +        AA  HQ+ + V  QT   
Sbjct: 294 -------PPSSPAPQETTAAPIT--TPNSSPTTLAPDTSETSAAPTHQTTTSVTTQTTTT 344

Query: 506 YEASSA 511
            + +SA
Sbjct: 345 KQPTSA 350



 Score = 39.7 bits (91), Expect = 0.008
 Identities = 61/305 (20%), Positives = 103/305 (33%), Gaps = 33/305 (10%)

Query: 269 FPALSQKMSPFKRQLSLRINE-----LPSTMQRKTDFPIKNAVPEVEGEAESISSLCSQI 323
           +P L     PF R+    +++     LP +      FP  +  P+   +  S+ +     
Sbjct: 48  YPGLLAHQKPFIRKSYKCLHKRCRPKLPPSPNNPPKFPNPHQPPKHPDKNSSVVNPTLVA 107

Query: 324 TNAFSTPEDPFSSAPMTK-PVTVVAPQSPTFQGTEWGQSSGAASPGLFQAGHRRTPSEAD 382
           T    +   P +S  +T  P     PQ+ T   +    ++ ++   L       +P+  D
Sbjct: 108 TTQIPSVTFPSASTKITTLPNVTFLPQNATTISSRENVNTSSSVATLAPVN---SPAPQD 164

Query: 383 RWLEEVSKSVRAQQPQASAAPLQPVLQPPPPTAISQ-PASPFQGNAFLTSQPVPVGVVPA 441
                 + S     P +S+AP +    PP P+A +Q P S         + P P    PA
Sbjct: 165 TTAAPPTPSATTPAPPSSSAPPETTAAPPTPSATTQAPPSSSAPPETTAAPPTPPATTPA 224

Query: 442 LQPAFVPAQS------------YPVANGMPYPAPNVPVVGITPSQMVANVFGTAGHPQAA 489
              +  P ++             P+++  P   P    V  TPS    +    +  P+  
Sbjct: 225 PPSSSAPPETTAAPPTPSATTPAPLSSSAP---PETTAVPPTPSATTLDPSSASAPPETT 281

Query: 490 HPHQSPSLVRQQTFPHYEASSATTSPFFKPPAQHLNGSAAFNGVDDGRLASADRH---TE 546
               +PS               T +P   P     N S      D    ++A  H   T 
Sbjct: 282 AAPPTPSATTPAPPSSPAPQETTAAPITTP-----NSSPTTLAPDTSETSAAPTHQTTTS 336

Query: 547 VPTGT 551
           V T T
Sbjct: 337 VTTQT 341



 Score = 30.4 bits (67), Expect = 4.8
 Identities = 32/136 (23%), Positives = 48/136 (35%), Gaps = 12/136 (8%)

Query: 221 PGNTAPSPSSPTSPTSDATTSLEMNNPHAIPRRHAPIEQLARQGSFRGFPALSQKMSPFK 280
           P ++AP  ++   PT  ATT        A P   AP E  A   +    PA +   +P  
Sbjct: 180 PSSSAPPETTAAPPTPSATT-------QAPPSSSAPPETTAAPPT---PPATTP--APPS 227

Query: 281 RQLSLRINELPSTMQRKTDFPIKNAVPEVEGEAESISSLCSQITNAFSTPEDPFSSAPMT 340
                     P T    T  P+ ++ P          S  +   ++ S P +  ++ P  
Sbjct: 228 SSAPPETTAAPPTPSATTPAPLSSSAPPETTAVPPTPSATTLDPSSASAPPETTAAPPTP 287

Query: 341 KPVTVVAPQSPTFQGT 356
              T   P SP  Q T
Sbjct: 288 SATTPAPPSSPAPQET 303


>gi|222418649 mucin 7, secreted precursor [Homo sapiens]
          Length = 377

 Score = 43.9 bits (102), Expect = 4e-04
 Identities = 69/306 (22%), Positives = 104/306 (33%), Gaps = 49/306 (16%)

Query: 228 PSSPTSPTSDATTSLEMNNPHAIPRRHAPIEQLARQGSFRG-------------FPALSQ 274
           P  P SP          NNP   P  H P +   +  S                FP+ S 
Sbjct: 72  PKLPPSP----------NNPPKFPNPHQPPKHPDKNSSVVNPTLVATTQIPSVTFPSAST 121

Query: 275 KMSPFKRQLSLRINELPSTMQRKTDFPIKNAVPEVEGEAESISSLCSQITNAFSTPEDPF 334
           K++       L  N    + +   +     A            +  +  T + +TP  P 
Sbjct: 122 KITTLPNVTFLPQNATTISSRENVNTSSSVATLAPVNSPAPQDTTAAPPTPSATTPAPPS 181

Query: 335 SSAPMTKPVTVVAPQSPTFQGTEWGQSSGA-----ASPGLFQAGHRRTPSEA---DRWLE 386
           SSAP   P T  AP +P+   T+   SS A     A+P    A     PS +   +    
Sbjct: 182 SSAP---PETTAAPPTPSAT-TQAPPSSSAPPETTAAPPTPPATTPAPPSSSAPPETTAA 237

Query: 387 EVSKSVRAQQPQASAAPLQPVLQPPPPTAIS-QPASPFQGNAFLTSQPVPVGVVPALQPA 445
             + S     P +S+AP +    PP P+A +  P+S         + P P    PA    
Sbjct: 238 PPTPSATTPAPLSSSAPPETTAVPPTPSATTLDPSSASAPPETTAAPPTPSATTPA---- 293

Query: 446 FVPAQSYPVANGMPYPAPNVPVVGITPSQMVANVFGTAGHPQAAHPHQSPSLVRQQTFPH 505
                  P ++  P      P+   TP+     +        AA  HQ+ + V  QT   
Sbjct: 294 -------PPSSPAPQETTAAPIT--TPNSSPTTLAPDTSETSAAPTHQTTTSVTTQTTTT 344

Query: 506 YEASSA 511
            + +SA
Sbjct: 345 KQPTSA 350



 Score = 39.7 bits (91), Expect = 0.008
 Identities = 61/305 (20%), Positives = 103/305 (33%), Gaps = 33/305 (10%)

Query: 269 FPALSQKMSPFKRQLSLRINE-----LPSTMQRKTDFPIKNAVPEVEGEAESISSLCSQI 323
           +P L     PF R+    +++     LP +      FP  +  P+   +  S+ +     
Sbjct: 48  YPGLLAHQKPFIRKSYKCLHKRCRPKLPPSPNNPPKFPNPHQPPKHPDKNSSVVNPTLVA 107

Query: 324 TNAFSTPEDPFSSAPMTK-PVTVVAPQSPTFQGTEWGQSSGAASPGLFQAGHRRTPSEAD 382
           T    +   P +S  +T  P     PQ+ T   +    ++ ++   L       +P+  D
Sbjct: 108 TTQIPSVTFPSASTKITTLPNVTFLPQNATTISSRENVNTSSSVATLAPVN---SPAPQD 164

Query: 383 RWLEEVSKSVRAQQPQASAAPLQPVLQPPPPTAISQ-PASPFQGNAFLTSQPVPVGVVPA 441
                 + S     P +S+AP +    PP P+A +Q P S         + P P    PA
Sbjct: 165 TTAAPPTPSATTPAPPSSSAPPETTAAPPTPSATTQAPPSSSAPPETTAAPPTPPATTPA 224

Query: 442 LQPAFVPAQS------------YPVANGMPYPAPNVPVVGITPSQMVANVFGTAGHPQAA 489
              +  P ++             P+++  P   P    V  TPS    +    +  P+  
Sbjct: 225 PPSSSAPPETTAAPPTPSATTPAPLSSSAP---PETTAVPPTPSATTLDPSSASAPPETT 281

Query: 490 HPHQSPSLVRQQTFPHYEASSATTSPFFKPPAQHLNGSAAFNGVDDGRLASADRH---TE 546
               +PS               T +P   P     N S      D    ++A  H   T 
Sbjct: 282 AAPPTPSATTPAPPSSPAPQETTAAPITTP-----NSSPTTLAPDTSETSAAPTHQTTTS 336

Query: 547 VPTGT 551
           V T T
Sbjct: 337 VTTQT 341



 Score = 30.4 bits (67), Expect = 4.8
 Identities = 32/136 (23%), Positives = 48/136 (35%), Gaps = 12/136 (8%)

Query: 221 PGNTAPSPSSPTSPTSDATTSLEMNNPHAIPRRHAPIEQLARQGSFRGFPALSQKMSPFK 280
           P ++AP  ++   PT  ATT        A P   AP E  A   +    PA +   +P  
Sbjct: 180 PSSSAPPETTAAPPTPSATT-------QAPPSSSAPPETTAAPPT---PPATTP--APPS 227

Query: 281 RQLSLRINELPSTMQRKTDFPIKNAVPEVEGEAESISSLCSQITNAFSTPEDPFSSAPMT 340
                     P T    T  P+ ++ P          S  +   ++ S P +  ++ P  
Sbjct: 228 SSAPPETTAAPPTPSATTPAPLSSSAPPETTAVPPTPSATTLDPSSASAPPETTAAPPTP 287

Query: 341 KPVTVVAPQSPTFQGT 356
              T   P SP  Q T
Sbjct: 288 SATTPAPPSSPAPQET 303


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.314    0.128    0.382 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 25,637,940
Number of Sequences: 37866
Number of extensions: 1374893
Number of successful extensions: 10138
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 48
Number of HSP's successfully gapped in prelim test: 587
Number of HSP's that attempted gapping in prelim test: 8156
Number of HSP's gapped (non-prelim): 2029
length of query: 592
length of database: 18,247,518
effective HSP length: 108
effective length of query: 484
effective length of database: 14,157,990
effective search space: 6852467160
effective search space used: 6852467160
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 65 (29.6 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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