Search of human proteins with 54144627

Search of human proteins with 54144627

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|54144627 numb homolog isoform 2 [Homo sapiens]
         (603 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|54144627 numb homolog isoform 2 [Homo sapiens]                    1225   0.0  
gi|54144625 numb homolog isoform 1 [Homo sapiens]                    1202   0.0  
gi|54144629 numb homolog isoform 4 [Homo sapiens]                    1193   0.0  
gi|20070356 numb homolog isoform 3 [Homo sapiens]                    1170   0.0  
gi|10863899 numb homolog (Drosophila)-like [Homo sapiens]             588   e-168
gi|7705318 GULP, engulfment adaptor PTB domain containing 1 [Hom...    84   5e-16
gi|132626790 low density lipoprotein receptor adaptor protein 1 ...    74   3e-13
gi|33350928 disabled homolog 1 [Homo sapiens]                          63   7e-10
gi|50511947 cajalin 2 isoform b [Homo sapiens]                         57   6e-08
gi|50511945 cajalin 2 isoform a [Homo sapiens]                         57   6e-08
gi|10047134 cajalin 2 isoform c [Homo sapiens]                         57   6e-08
gi|140161500 ankyrin repeat and sterile alpha motif domain conta...    54   3e-07
gi|19718731 bromodomain-containing protein 4 isoform long [Homo ...    53   7e-07
gi|31317301 nitric oxide synthase 1 (neuronal) adaptor protein i...    50   6e-06
gi|21327715 transcription elongation regulator 1 isoform 1 [Homo...    50   6e-06
gi|149773456 hypothetical protein LOC643314 [Homo sapiens]             49   1e-05
gi|148491082 disabled homolog 2 [Homo sapiens]                         48   3e-05
gi|91208418 transcription elongation regulator 1 isoform 2 [Homo...    48   3e-05
gi|153792074 proline rich 12 [Homo sapiens]                            48   3e-05
gi|189181724 proteoglycan 4 isoform D [Homo sapiens]                   47   5e-05
gi|189181722 proteoglycan 4 isoform C [Homo sapiens]                   47   5e-05
gi|189181720 proteoglycan 4 isoform B [Homo sapiens]                   47   5e-05
gi|67190163 proteoglycan 4 isoform A [Homo sapiens]                    47   5e-05
gi|146219843 Snf2-related CBP activator protein [Homo sapiens]         47   7e-05
gi|91208420 bassoon protein [Homo sapiens]                             45   1e-04
gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapi...    45   2e-04
gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapi...    45   2e-04
gi|7662236 TSC22 domain family, member 2 [Homo sapiens]                44   3e-04
gi|222418647 mucin 7, secreted precursor [Homo sapiens]                44   4e-04
gi|222418649 mucin 7, secreted precursor [Homo sapiens]                44   4e-04

>gi|54144627 numb homolog isoform 2 [Homo sapiens]
          Length = 603

 Score = 1225 bits (3170), Expect = 0.0
 Identities = 603/603 (100%), Positives = 603/603 (100%)

Query: 1   MNKLRQSFRRKKDVYVPEASRPHQWQTDEEGVRTGKCSFPVKYLGHVEVDESRGMHICED 60
           MNKLRQSFRRKKDVYVPEASRPHQWQTDEEGVRTGKCSFPVKYLGHVEVDESRGMHICED
Sbjct: 1   MNKLRQSFRRKKDVYVPEASRPHQWQTDEEGVRTGKCSFPVKYLGHVEVDESRGMHICED 60

Query: 61  AVKRLKAERKFFKGFFGKTGKKAVKAVLWVSADGLRVVDEKTKDLIVDQTIEKVSFCAPD 120
           AVKRLKAERKFFKGFFGKTGKKAVKAVLWVSADGLRVVDEKTKDLIVDQTIEKVSFCAPD
Sbjct: 61  AVKRLKAERKFFKGFFGKTGKKAVKAVLWVSADGLRVVDEKTKDLIVDQTIEKVSFCAPD 120

Query: 121 RNFDRAFSYICRDGTTRRWICHCFMAVKDTGERLSHAVGCAFAACLERKQKREKECGVTA 180
           RNFDRAFSYICRDGTTRRWICHCFMAVKDTGERLSHAVGCAFAACLERKQKREKECGVTA
Sbjct: 121 RNFDRAFSYICRDGTTRRWICHCFMAVKDTGERLSHAVGCAFAACLERKQKREKECGVTA 180

Query: 181 TFDASRTTFTREGSFRVTTATEQAEREEIMKQMQDAKKAETDKIVVGSSVAPGNTAPSPS 240
           TFDASRTTFTREGSFRVTTATEQAEREEIMKQMQDAKKAETDKIVVGSSVAPGNTAPSPS
Sbjct: 181 TFDASRTTFTREGSFRVTTATEQAEREEIMKQMQDAKKAETDKIVVGSSVAPGNTAPSPS 240

Query: 241 SPTSPTSDATTSLEMNNPHAIPRRHAPIEQLARQGSFRGFPALSQKMSPFKRQLSLRINE 300
           SPTSPTSDATTSLEMNNPHAIPRRHAPIEQLARQGSFRGFPALSQKMSPFKRQLSLRINE
Sbjct: 241 SPTSPTSDATTSLEMNNPHAIPRRHAPIEQLARQGSFRGFPALSQKMSPFKRQLSLRINE 300

Query: 301 LPSTMQRKTDFPIKNAVPEVEGEAESISSLCSQITNAFSTPEDPFSSAPMTKPVTVVAPQ 360
           LPSTMQRKTDFPIKNAVPEVEGEAESISSLCSQITNAFSTPEDPFSSAPMTKPVTVVAPQ
Sbjct: 301 LPSTMQRKTDFPIKNAVPEVEGEAESISSLCSQITNAFSTPEDPFSSAPMTKPVTVVAPQ 360

Query: 361 SPTFQGTEWGQSSGAASPGLFQAGHRRTPSEADRWLEEVSKSVRAQQPQASAAPLQPVLQ 420
           SPTFQGTEWGQSSGAASPGLFQAGHRRTPSEADRWLEEVSKSVRAQQPQASAAPLQPVLQ
Sbjct: 361 SPTFQGTEWGQSSGAASPGLFQAGHRRTPSEADRWLEEVSKSVRAQQPQASAAPLQPVLQ 420

Query: 421 PPPPTAISQPASPFQGNAFLTSQPVPVGVVPALQPAFVPAQSYPVANGMPYPAPNVPVVG 480
           PPPPTAISQPASPFQGNAFLTSQPVPVGVVPALQPAFVPAQSYPVANGMPYPAPNVPVVG
Sbjct: 421 PPPPTAISQPASPFQGNAFLTSQPVPVGVVPALQPAFVPAQSYPVANGMPYPAPNVPVVG 480

Query: 481 ITPSQMVANVFGTAGHPQAAHPHQSPSLVRQQTFPHYEASSATTSPFFKPPAQHLNGSAA 540
           ITPSQMVANVFGTAGHPQAAHPHQSPSLVRQQTFPHYEASSATTSPFFKPPAQHLNGSAA
Sbjct: 481 ITPSQMVANVFGTAGHPQAAHPHQSPSLVRQQTFPHYEASSATTSPFFKPPAQHLNGSAA 540

Query: 541 FNGVDDGRLASADRHTEVPTGTCPVDPFEAQWAALENKSKQRTNPSPTNPFSSDLQKTFE 600
           FNGVDDGRLASADRHTEVPTGTCPVDPFEAQWAALENKSKQRTNPSPTNPFSSDLQKTFE
Sbjct: 541 FNGVDDGRLASADRHTEVPTGTCPVDPFEAQWAALENKSKQRTNPSPTNPFSSDLQKTFE 600

Query: 601 IEL 603
           IEL
Sbjct: 601 IEL 603


>gi|54144625 numb homolog isoform 1 [Homo sapiens]
          Length = 651

 Score = 1202 bits (3111), Expect = 0.0
 Identities = 603/651 (92%), Positives = 603/651 (92%), Gaps = 48/651 (7%)

Query: 1   MNKLRQSFRRKKDVYVPEASRPHQWQTDEEGVRTGKCSFPVKYLGHVEVDESRGMHICED 60
           MNKLRQSFRRKKDVYVPEASRPHQWQTDEEGVRTGKCSFPVKYLGHVEVDESRGMHICED
Sbjct: 1   MNKLRQSFRRKKDVYVPEASRPHQWQTDEEGVRTGKCSFPVKYLGHVEVDESRGMHICED 60

Query: 61  AVKRLKAERKFFKGFFGKTGKKAVKAVLWVSADGLRVVDEKTKDLIVDQTIEKVSFCAPD 120
           AVKRLKAERKFFKGFFGKTGKKAVKAVLWVSADGLRVVDEKTKDLIVDQTIEKVSFCAPD
Sbjct: 61  AVKRLKAERKFFKGFFGKTGKKAVKAVLWVSADGLRVVDEKTKDLIVDQTIEKVSFCAPD 120

Query: 121 RNFDRAFSYICRDGTTRRWICHCFMAVKDTGERLSHAVGCAFAACLERKQKREKECGVTA 180
           RNFDRAFSYICRDGTTRRWICHCFMAVKDTGERLSHAVGCAFAACLERKQKREKECGVTA
Sbjct: 121 RNFDRAFSYICRDGTTRRWICHCFMAVKDTGERLSHAVGCAFAACLERKQKREKECGVTA 180

Query: 181 TFDASRTTFTREGSFRVTTATEQAEREEIMKQMQDAKKAETDKIVVGSSVAPGNTAPSPS 240
           TFDASRTTFTREGSFRVTTATEQAEREEIMKQMQDAKKAETDKIVVGSSVAPGNTAPSPS
Sbjct: 181 TFDASRTTFTREGSFRVTTATEQAEREEIMKQMQDAKKAETDKIVVGSSVAPGNTAPSPS 240

Query: 241 SPTSPTSDATTSLEMNNPHAIPRRHAPIEQLARQGSFRGFPALSQKMSPFKRQLSLRINE 300
           SPTSPTSDATTSLEMNNPHAIPRRHAPIEQLARQGSFRGFPALSQKMSPFKRQLSLRINE
Sbjct: 241 SPTSPTSDATTSLEMNNPHAIPRRHAPIEQLARQGSFRGFPALSQKMSPFKRQLSLRINE 300

Query: 301 LPSTMQRKTDFPIKNAVPEVEGEAESISSLCSQITNAFSTPEDPFSSAPMTKPVTVVAPQ 360
           LPSTMQRKTDFPIKNAVPEVEGEAESISSLCSQITNAFSTPEDPFSSAPMTKPVTVVAPQ
Sbjct: 301 LPSTMQRKTDFPIKNAVPEVEGEAESISSLCSQITNAFSTPEDPFSSAPMTKPVTVVAPQ 360

Query: 361 SPTFQ------------------------------------------------GTEWGQS 372
           SPTFQ                                                GTEWGQS
Sbjct: 361 SPTFQANGTDSAFHVLAKPAHTALAPVAMPVRETNPWAHAPDAANKEIAATCSGTEWGQS 420

Query: 373 SGAASPGLFQAGHRRTPSEADRWLEEVSKSVRAQQPQASAAPLQPVLQPPPPTAISQPAS 432
           SGAASPGLFQAGHRRTPSEADRWLEEVSKSVRAQQPQASAAPLQPVLQPPPPTAISQPAS
Sbjct: 421 SGAASPGLFQAGHRRTPSEADRWLEEVSKSVRAQQPQASAAPLQPVLQPPPPTAISQPAS 480

Query: 433 PFQGNAFLTSQPVPVGVVPALQPAFVPAQSYPVANGMPYPAPNVPVVGITPSQMVANVFG 492
           PFQGNAFLTSQPVPVGVVPALQPAFVPAQSYPVANGMPYPAPNVPVVGITPSQMVANVFG
Sbjct: 481 PFQGNAFLTSQPVPVGVVPALQPAFVPAQSYPVANGMPYPAPNVPVVGITPSQMVANVFG 540

Query: 493 TAGHPQAAHPHQSPSLVRQQTFPHYEASSATTSPFFKPPAQHLNGSAAFNGVDDGRLASA 552
           TAGHPQAAHPHQSPSLVRQQTFPHYEASSATTSPFFKPPAQHLNGSAAFNGVDDGRLASA
Sbjct: 541 TAGHPQAAHPHQSPSLVRQQTFPHYEASSATTSPFFKPPAQHLNGSAAFNGVDDGRLASA 600

Query: 553 DRHTEVPTGTCPVDPFEAQWAALENKSKQRTNPSPTNPFSSDLQKTFEIEL 603
           DRHTEVPTGTCPVDPFEAQWAALENKSKQRTNPSPTNPFSSDLQKTFEIEL
Sbjct: 601 DRHTEVPTGTCPVDPFEAQWAALENKSKQRTNPSPTNPFSSDLQKTFEIEL 651


>gi|54144629 numb homolog isoform 4 [Homo sapiens]
          Length = 592

 Score = 1193 bits (3087), Expect = 0.0
 Identities = 592/603 (98%), Positives = 592/603 (98%), Gaps = 11/603 (1%)

Query: 1   MNKLRQSFRRKKDVYVPEASRPHQWQTDEEGVRTGKCSFPVKYLGHVEVDESRGMHICED 60
           MNKLRQSFRRKKDVYVPEASRPHQWQTDEEGVRTGKCSFPVKYLGHVEVDESRGMHICED
Sbjct: 1   MNKLRQSFRRKKDVYVPEASRPHQWQTDEEGVRTGKCSFPVKYLGHVEVDESRGMHICED 60

Query: 61  AVKRLKAERKFFKGFFGKTGKKAVKAVLWVSADGLRVVDEKTKDLIVDQTIEKVSFCAPD 120
           AVKRLKA           TGKKAVKAVLWVSADGLRVVDEKTKDLIVDQTIEKVSFCAPD
Sbjct: 61  AVKRLKA-----------TGKKAVKAVLWVSADGLRVVDEKTKDLIVDQTIEKVSFCAPD 109

Query: 121 RNFDRAFSYICRDGTTRRWICHCFMAVKDTGERLSHAVGCAFAACLERKQKREKECGVTA 180
           RNFDRAFSYICRDGTTRRWICHCFMAVKDTGERLSHAVGCAFAACLERKQKREKECGVTA
Sbjct: 110 RNFDRAFSYICRDGTTRRWICHCFMAVKDTGERLSHAVGCAFAACLERKQKREKECGVTA 169

Query: 181 TFDASRTTFTREGSFRVTTATEQAEREEIMKQMQDAKKAETDKIVVGSSVAPGNTAPSPS 240
           TFDASRTTFTREGSFRVTTATEQAEREEIMKQMQDAKKAETDKIVVGSSVAPGNTAPSPS
Sbjct: 170 TFDASRTTFTREGSFRVTTATEQAEREEIMKQMQDAKKAETDKIVVGSSVAPGNTAPSPS 229

Query: 241 SPTSPTSDATTSLEMNNPHAIPRRHAPIEQLARQGSFRGFPALSQKMSPFKRQLSLRINE 300
           SPTSPTSDATTSLEMNNPHAIPRRHAPIEQLARQGSFRGFPALSQKMSPFKRQLSLRINE
Sbjct: 230 SPTSPTSDATTSLEMNNPHAIPRRHAPIEQLARQGSFRGFPALSQKMSPFKRQLSLRINE 289

Query: 301 LPSTMQRKTDFPIKNAVPEVEGEAESISSLCSQITNAFSTPEDPFSSAPMTKPVTVVAPQ 360
           LPSTMQRKTDFPIKNAVPEVEGEAESISSLCSQITNAFSTPEDPFSSAPMTKPVTVVAPQ
Sbjct: 290 LPSTMQRKTDFPIKNAVPEVEGEAESISSLCSQITNAFSTPEDPFSSAPMTKPVTVVAPQ 349

Query: 361 SPTFQGTEWGQSSGAASPGLFQAGHRRTPSEADRWLEEVSKSVRAQQPQASAAPLQPVLQ 420
           SPTFQGTEWGQSSGAASPGLFQAGHRRTPSEADRWLEEVSKSVRAQQPQASAAPLQPVLQ
Sbjct: 350 SPTFQGTEWGQSSGAASPGLFQAGHRRTPSEADRWLEEVSKSVRAQQPQASAAPLQPVLQ 409

Query: 421 PPPPTAISQPASPFQGNAFLTSQPVPVGVVPALQPAFVPAQSYPVANGMPYPAPNVPVVG 480
           PPPPTAISQPASPFQGNAFLTSQPVPVGVVPALQPAFVPAQSYPVANGMPYPAPNVPVVG
Sbjct: 410 PPPPTAISQPASPFQGNAFLTSQPVPVGVVPALQPAFVPAQSYPVANGMPYPAPNVPVVG 469

Query: 481 ITPSQMVANVFGTAGHPQAAHPHQSPSLVRQQTFPHYEASSATTSPFFKPPAQHLNGSAA 540
           ITPSQMVANVFGTAGHPQAAHPHQSPSLVRQQTFPHYEASSATTSPFFKPPAQHLNGSAA
Sbjct: 470 ITPSQMVANVFGTAGHPQAAHPHQSPSLVRQQTFPHYEASSATTSPFFKPPAQHLNGSAA 529

Query: 541 FNGVDDGRLASADRHTEVPTGTCPVDPFEAQWAALENKSKQRTNPSPTNPFSSDLQKTFE 600
           FNGVDDGRLASADRHTEVPTGTCPVDPFEAQWAALENKSKQRTNPSPTNPFSSDLQKTFE
Sbjct: 530 FNGVDDGRLASADRHTEVPTGTCPVDPFEAQWAALENKSKQRTNPSPTNPFSSDLQKTFE 589

Query: 601 IEL 603
           IEL
Sbjct: 590 IEL 592


>gi|20070356 numb homolog isoform 3 [Homo sapiens]
          Length = 640

 Score = 1170 bits (3028), Expect = 0.0
 Identities = 592/651 (90%), Positives = 592/651 (90%), Gaps = 59/651 (9%)

Query: 1   MNKLRQSFRRKKDVYVPEASRPHQWQTDEEGVRTGKCSFPVKYLGHVEVDESRGMHICED 60
           MNKLRQSFRRKKDVYVPEASRPHQWQTDEEGVRTGKCSFPVKYLGHVEVDESRGMHICED
Sbjct: 1   MNKLRQSFRRKKDVYVPEASRPHQWQTDEEGVRTGKCSFPVKYLGHVEVDESRGMHICED 60

Query: 61  AVKRLKAERKFFKGFFGKTGKKAVKAVLWVSADGLRVVDEKTKDLIVDQTIEKVSFCAPD 120
           AVKRLKA           TGKKAVKAVLWVSADGLRVVDEKTKDLIVDQTIEKVSFCAPD
Sbjct: 61  AVKRLKA-----------TGKKAVKAVLWVSADGLRVVDEKTKDLIVDQTIEKVSFCAPD 109

Query: 121 RNFDRAFSYICRDGTTRRWICHCFMAVKDTGERLSHAVGCAFAACLERKQKREKECGVTA 180
           RNFDRAFSYICRDGTTRRWICHCFMAVKDTGERLSHAVGCAFAACLERKQKREKECGVTA
Sbjct: 110 RNFDRAFSYICRDGTTRRWICHCFMAVKDTGERLSHAVGCAFAACLERKQKREKECGVTA 169

Query: 181 TFDASRTTFTREGSFRVTTATEQAEREEIMKQMQDAKKAETDKIVVGSSVAPGNTAPSPS 240
           TFDASRTTFTREGSFRVTTATEQAEREEIMKQMQDAKKAETDKIVVGSSVAPGNTAPSPS
Sbjct: 170 TFDASRTTFTREGSFRVTTATEQAEREEIMKQMQDAKKAETDKIVVGSSVAPGNTAPSPS 229

Query: 241 SPTSPTSDATTSLEMNNPHAIPRRHAPIEQLARQGSFRGFPALSQKMSPFKRQLSLRINE 300
           SPTSPTSDATTSLEMNNPHAIPRRHAPIEQLARQGSFRGFPALSQKMSPFKRQLSLRINE
Sbjct: 230 SPTSPTSDATTSLEMNNPHAIPRRHAPIEQLARQGSFRGFPALSQKMSPFKRQLSLRINE 289

Query: 301 LPSTMQRKTDFPIKNAVPEVEGEAESISSLCSQITNAFSTPEDPFSSAPMTKPVTVVAPQ 360
           LPSTMQRKTDFPIKNAVPEVEGEAESISSLCSQITNAFSTPEDPFSSAPMTKPVTVVAPQ
Sbjct: 290 LPSTMQRKTDFPIKNAVPEVEGEAESISSLCSQITNAFSTPEDPFSSAPMTKPVTVVAPQ 349

Query: 361 SPTFQ------------------------------------------------GTEWGQS 372
           SPTFQ                                                GTEWGQS
Sbjct: 350 SPTFQANGTDSAFHVLAKPAHTALAPVAMPVRETNPWAHAPDAANKEIAATCSGTEWGQS 409

Query: 373 SGAASPGLFQAGHRRTPSEADRWLEEVSKSVRAQQPQASAAPLQPVLQPPPPTAISQPAS 432
           SGAASPGLFQAGHRRTPSEADRWLEEVSKSVRAQQPQASAAPLQPVLQPPPPTAISQPAS
Sbjct: 410 SGAASPGLFQAGHRRTPSEADRWLEEVSKSVRAQQPQASAAPLQPVLQPPPPTAISQPAS 469

Query: 433 PFQGNAFLTSQPVPVGVVPALQPAFVPAQSYPVANGMPYPAPNVPVVGITPSQMVANVFG 492
           PFQGNAFLTSQPVPVGVVPALQPAFVPAQSYPVANGMPYPAPNVPVVGITPSQMVANVFG
Sbjct: 470 PFQGNAFLTSQPVPVGVVPALQPAFVPAQSYPVANGMPYPAPNVPVVGITPSQMVANVFG 529

Query: 493 TAGHPQAAHPHQSPSLVRQQTFPHYEASSATTSPFFKPPAQHLNGSAAFNGVDDGRLASA 552
           TAGHPQAAHPHQSPSLVRQQTFPHYEASSATTSPFFKPPAQHLNGSAAFNGVDDGRLASA
Sbjct: 530 TAGHPQAAHPHQSPSLVRQQTFPHYEASSATTSPFFKPPAQHLNGSAAFNGVDDGRLASA 589

Query: 553 DRHTEVPTGTCPVDPFEAQWAALENKSKQRTNPSPTNPFSSDLQKTFEIEL 603
           DRHTEVPTGTCPVDPFEAQWAALENKSKQRTNPSPTNPFSSDLQKTFEIEL
Sbjct: 590 DRHTEVPTGTCPVDPFEAQWAALENKSKQRTNPSPTNPFSSDLQKTFEIEL 640


>gi|10863899 numb homolog (Drosophila)-like [Homo sapiens]
          Length = 609

 Score =  588 bits (1517), Expect = e-168
 Identities = 348/636 (54%), Positives = 402/636 (63%), Gaps = 101/636 (15%)

Query: 1   MNKLRQSFRRKKDVYVPEASRPHQWQTDEEGVRTGKCSFPVKYLGHVEVDESRGMHICED 60
           MNKLRQS RR+K  YVPEASRPHQWQ DE+ VR G CSFPV+YLGHVEV+ESRGMH+CED
Sbjct: 42  MNKLRQSLRRRKPAYVPEASRPHQWQADEDAVRKGTCSFPVRYLGHVEVEESRGMHVCED 101

Query: 61  AVKRLKAERKFFKGFFGKTGKKAVKAVLWVSADGLRVVDEKTKDLIVDQTIEKVSFCAPD 120
           AVK+LKA            G+K+VK+VLWVSADGLRVVD+KTKDL+VDQTIEKVSFCAPD
Sbjct: 102 AVKKLKA-----------MGRKSVKSVLWVSADGLRVVDDKTKDLLVDQTIEKVSFCAPD 150

Query: 121 RNFDRAFSYICRDGTTRRWICHCFMAVKDTGERLSHAVGCAFAACLERKQKREKECGVTA 180
           RN D+AFSYICRDGTTRRWICHCF+A+KD+GERLSHAVGCAFAACLERKQ+REKECGVTA
Sbjct: 151 RNLDKAFSYICRDGTTRRWICHCFLALKDSGERLSHAVGCAFAACLERKQRREKECGVTA 210

Query: 181 TFDASRTTFTREGSFRVTTATEQAEREEIMKQMQDAKKAETDKIVVGSSVAPGNTAPSPS 240
            FDASRT+F REGSFR++     AERE       D KKAE        +VAPG   P   
Sbjct: 211 AFDASRTSFAREGSFRLSGGGRPAERE-----APDKKKAEA---AAAPTVAPGPAQPGHV 262

Query: 241 SPTSPTSDATTSLEMNNP-------HAIPRRHAPIEQLARQGSFRGFPALSQKMSPFKRQ 293
           SPT  T+      E   P        AIPRRHAP+EQL RQGSFRGFPALSQK SPFKRQ
Sbjct: 263 SPTPATTSPGEKGEAGTPVAAGTTAAAIPRRHAPLEQLVRQGSFRGFPALSQKNSPFKRQ 322

Query: 294 LSLRINELPSTMQRKTDFPIKNAVPEVE----GEAESISSLCSQITNAFSTPEDPFSSAP 349
           LSLR+NELPST+QR+TDF +K  VPE+E    G+++SI++LC+QI+++F++   P    P
Sbjct: 323 LSLRLNELPSTLQRRTDFQVKGTVPEMEPPGAGDSDSINALCTQISSSFASAGAPAPGPP 382

Query: 350 MTKPVTVVAPQSPTFQGTE-WGQSSGAASPGLFQAGHRRTPSEADRWLEEVSKSVRAQQP 408
                       P   GT  WG+ S       FQ GH+RTPSEA+RWLEEVS+  +AQQ 
Sbjct: 383 ------------PATTGTSAWGEPS-VPPAAAFQPGHKRTPSEAERWLEEVSQVAKAQQQ 429

Query: 409 Q-----------------ASAAP---LQPVLQPPPPTAISQPASPFQGNAFLTSQPVPVG 448
           Q                 AS AP   + P LQP P       A+P Q   FL        
Sbjct: 430 QQQQQQQQQQQQQQQQQAASVAPVPTMPPALQPFPAPVGPFDAAPAQVAVFLPP------ 483

Query: 449 VVPALQPAFVPAQSYPVANGMPY-PAPNVPVVGITPSQMVANVFGTAGHPQAAHPHQSPS 507
             P +QP FVPA  YP   G+ Y P P VPVVGITPSQMVAN F +A   Q   P  +  
Sbjct: 484 --PHMQPPFVPA--YP---GLGYPPMPRVPVVGITPSQMVANAFCSAAQLQ---PQPATL 533

Query: 508 LVRQQTFPHYEASSATTSPFFKPPAQHLNGSAAFNGVDDGRLASADRHTEVPTGTCPVDP 567
           L +   FP     SA  S     P    NG+                    P     +DP
Sbjct: 534 LGKAGAFPPPAIPSAPGSQARPRP----NGAPW-------------PPEPAPAPAPELDP 576

Query: 568 FEAQWAALENKSKQRTNPSPTNPFSSDLQKTFEIEL 603
           FEAQWAALE K+   T   P+NPFS DLQKTFEIEL
Sbjct: 577 FEAQWAALEGKA---TVEKPSNPFSGDLQKTFEIEL 609


>gi|7705318 GULP, engulfment adaptor PTB domain containing 1 [Homo
           sapiens]
          Length = 304

 Score = 83.6 bits (205), Expect = 5e-16
 Identities = 63/264 (23%), Positives = 125/264 (47%), Gaps = 31/264 (11%)

Query: 4   LRQSFRRKKDVYVPEASRPHQWQTDEEGVRTGKCSFPVKYLGHVEVDESRGMHICEDAVK 63
           + ++F RKKD           W    E +      +  K+LG  EV++ +G  +  DAV+
Sbjct: 1   MNRAFSRKKD---------KTWMHTPEALSKHFIPYNAKFLGSTEVEQPKGTEVVRDAVR 51

Query: 64  RLKAERKFFKGFFGKTGKKAVKAVLWVSADGLRVVDEKTKDLIVDQTIEKVSFCAPDRNF 123
           +LK  R   K      G+K  K  L +S  G+++++ KTK++  +  + ++SFCA D+  
Sbjct: 52  KLKFARHIKKS----EGQKIPKVELQISIYGVKILEPKTKEVQHNCQLHRISFCADDKTD 107

Query: 124 DRAFSYICRDGTTRRWICHCFMAVKDTGERLSHAVGCAFAACLERKQKREKECGVTATFD 183
            R F++IC+D  + + +C+ F + K   E ++  +G AF    +   ++  E G      
Sbjct: 108 KRIFTFICKDSESNKHLCYVFDSEK-CAEEITLTIGQAF----DLAYRKFLESG------ 156

Query: 184 ASRTTFTREGSFRVTTATEQAERE--EIMKQMQDAKKAETDKIVVGSSVAPGNTAPSPSS 241
             +   TR+    +    +  E E  E+  ++QD +    +++ +    AP   + +P S
Sbjct: 157 -GKDVETRKQIAGLQKRIQDLETENMELKNKVQDLE----NQLRITQVSAPPAGSMTPKS 211

Query: 242 PTSPTSDATTSLEMNNPHAIPRRH 265
           P++   D      +++  ++P R+
Sbjct: 212 PSTDIFDMIPFSPISHQSSMPTRN 235


>gi|132626790 low density lipoprotein receptor adaptor protein 1
           [Homo sapiens]
          Length = 308

 Score = 74.3 bits (181), Expect = 3e-13
 Identities = 63/243 (25%), Positives = 103/243 (42%), Gaps = 35/243 (14%)

Query: 22  PHQWQTDEEGVRTGKCSFPVKYLGHVEVDESRGMHICEDAVKRLKAERKFFKGFFGKTGK 81
           P  W    E +  G   F +KYLG   V++ +G  +   A+KR+ A  K        +GK
Sbjct: 32  PENWTDTRETLLEGML-FSLKYLGMTLVEQPKGEELSAAAIKRIVATAK-------ASGK 83

Query: 82  KAVKAVLWVSADGLRVVDEKTKDLIVDQTIEKVSFCAPDRNFDRAFSYICRDGTTRRWIC 141
           K  K  L VS  G+ + D  T  LI + +I ++S+C  D+  D+ F+YI +    +   C
Sbjct: 84  KLQKVTLKVSPRGIILTDNLTNQLIENVSIYRISYCTADKMHDKVFAYIAQSQHNQSLEC 143

Query: 142 HCFMAVK-DTGERLSHAVGCAFAACLE--RKQKREKECGVTATFDASRTTFTREGSFRVT 198
           H F+  K    + ++  V  AF    E  +  K EKE          R   ++EG     
Sbjct: 144 HAFLCTKRKMAQAVTLTVAQAFKVAFEFWQVSKEEKE---------KRDKASQEGG---- 190

Query: 199 TATEQAEREEIMKQMQDAKKAETDKIVVGSSVAPGNTAPSPSSPTSPTSDATTSLEMNNP 258
                    +++   QD   +    +  G+ +    TA +P S  S  ++ T   E+  P
Sbjct: 191 ---------DVLGARQDCTPSLKSLVATGNLLDLEETAKAPLSTVS--ANTTNMDEVPRP 239

Query: 259 HAI 261
            A+
Sbjct: 240 QAL 242


>gi|33350928 disabled homolog 1 [Homo sapiens]
          Length = 555

 Score = 63.2 bits (152), Expect = 7e-10
 Identities = 117/546 (21%), Positives = 200/546 (36%), Gaps = 82/546 (15%)

Query: 30  EGVRTGKCSFPVKYLGHVEVDESRGMHICEDAVKRLKAERKFFKGFFGKTGKKAVKAVLW 89
           EGVR     +  K +G  EV  +RG  +C+D++ +LK       G   K G+   K  L 
Sbjct: 38  EGVR-----YKAKLIGIDEVSAARGDKLCQDSMMKLKG---VVAGARSK-GEHKQKIFLT 88

Query: 90  VSADGLRVVDEKTKDLIVDQTIEKVSFCAPDRNFDRAFSYIC-RDGTTRRWICHCFMAVK 148
           +S  G+++ DEKT  L     + ++S+ A D    RAF Y+C ++G       H F+A+K
Sbjct: 89  ISFGGIKIFDEKTGALQHHHAVHEISYIAKDITDHRAFGYVCGKEGN------HRFVAIK 142

Query: 149 ----------DTGERLSHAVGCAFAACLERKQKREKECGVTA-----------------T 181
                     D  +             LE+K +++K+C                      
Sbjct: 143 TAQAAEPVILDLRDLFQLIYELKQREELEKKAQKDKQCEQAVYQTILEEDVEDPVYQYIV 202

Query: 182 FDAS----RTTFTREGSFRVTTATEQAEREEIMKQMQDAKKAETDKIVVGSSVAPGNTAP 237
           F+A     R   T E  ++V T+ ++    ++ K    +   + +     S+     + P
Sbjct: 203 FEAGHEPIRDPETEENIYQVPTSQKKEGVYDVPKSQPVSAVTQLELFGDMSTPPDITSPP 262

Query: 238 SPSSPTS---PTSDATTSLEMNNPHAIPRRHAPIEQLARQGSFRGFPALSQKMSPFKRQL 294
           +P++P     P+S  T     +   ++P   A +          G+ A+   +  F  Q 
Sbjct: 263 TPATPGDAFIPSSSQTLPASADVFSSVPFGTAAVPS--------GYVAMGAVLPSFWGQQ 314

Query: 295 SLRINELPSTMQRKTDFPIKNAVPEVEGEAESISSLCSQITNAFSTPEDPFSSAPMTKPV 354
            L   ++    Q     P+   +P  +  A     L       + T    F  A      
Sbjct: 315 PLVQQQMVMGAQP----PVAQVMPGAQPIAWGQPGLFPATQQPWPTVAGQFPPAAFMPTQ 370

Query: 355 TVVAPQSPTFQGTEWGQSSGAASPGLFQAGHRRTPSEADRWLEEVSKSVRAQQPQASAAP 414
           TV+   +  FQG     +  A  PG   +   R+  + D+  +++ K        A   P
Sbjct: 371 TVMPLPAAMFQGP---LTPLATVPGTSDS--TRSSPQTDKPRQKMGKETFKDFQMAQPPP 425

Query: 415 LQPVLQPPPP--TAISQPASPFQGNAFLTSQPVPVGVVPALQPAFVPAQSY-PVANGMPY 471
           + P  +P  P  T  S+  S +     +             Q    P  S  P  N  P 
Sbjct: 426 V-PSRKPDQPSLTCTSEAFSSYFNKVGVAQDTDDCDDFDISQLNLTPVTSTTPSTNSPPT 484

Query: 472 PAPNVPVVGITPSQMVANVFGTAGHPQA----AHPHQSPSLVRQQTFPHYEASSATTSPF 527
           PAP       +PS+  A+    A  P          +SPS   +Q  P    +S+ + PF
Sbjct: 485 PAPRQS----SPSKSSAS---HASDPTTDDIFEEGFESPSKSEEQEAPDGSQASSNSDPF 537

Query: 528 FKPPAQ 533
            +P  +
Sbjct: 538 GEPSGE 543


>gi|50511947 cajalin 2 isoform b [Homo sapiens]
          Length = 510

 Score = 56.6 bits (135), Expect = 6e-08
 Identities = 38/129 (29%), Positives = 59/129 (45%), Gaps = 5/129 (3%)

Query: 19  ASRPHQ-WQTDEEGVRTGKCSFPVKYLGHVEVDESRGMHICEDAVKRLKAERKFFKGFFG 77
           AS P Q WQ   E +    C +   YLG + + E RG    +DA  +++A  +       
Sbjct: 291 ASTPVQYWQHHPEKLIFQSCDYKAFYLGSMLIKELRGTESTQDACAKMRANCQKST---- 346

Query: 78  KTGKKAVKAVLWVSADGLRVVDEKTKDLIVDQTIEKVSFCAPDRNFDRAFSYICRDGTTR 137
           +  KK    +L VS  G++ +D   K++I +  I  +S  A D      F+YI +D  + 
Sbjct: 347 EQMKKVPTIILSVSYKGVKFIDATNKNIIAEHEIRNISCAAQDPEDLSTFAYITKDLKSN 406

Query: 138 RWICHCFMA 146
              CH F A
Sbjct: 407 HHYCHVFTA 415


>gi|50511945 cajalin 2 isoform a [Homo sapiens]
          Length = 1248

 Score = 56.6 bits (135), Expect = 6e-08
 Identities = 38/129 (29%), Positives = 59/129 (45%), Gaps = 5/129 (3%)

Query: 19   ASRPHQ-WQTDEEGVRTGKCSFPVKYLGHVEVDESRGMHICEDAVKRLKAERKFFKGFFG 77
            AS P Q WQ   E +    C +   YLG + + E RG    +DA  +++A  +       
Sbjct: 1041 ASTPVQYWQHHPEKLIFQSCDYKAFYLGSMLIKELRGTESTQDACAKMRANCQKST---- 1096

Query: 78   KTGKKAVKAVLWVSADGLRVVDEKTKDLIVDQTIEKVSFCAPDRNFDRAFSYICRDGTTR 137
            +  KK    +L VS  G++ +D   K++I +  I  +S  A D      F+YI +D  + 
Sbjct: 1097 EQMKKVPTIILSVSYKGVKFIDATNKNIIAEHEIRNISCAAQDPEDLSTFAYITKDLKSN 1156

Query: 138  RWICHCFMA 146
               CH F A
Sbjct: 1157 HHYCHVFTA 1165


>gi|10047134 cajalin 2 isoform c [Homo sapiens]
          Length = 414

 Score = 56.6 bits (135), Expect = 6e-08
 Identities = 38/129 (29%), Positives = 59/129 (45%), Gaps = 5/129 (3%)

Query: 19  ASRPHQ-WQTDEEGVRTGKCSFPVKYLGHVEVDESRGMHICEDAVKRLKAERKFFKGFFG 77
           AS P Q WQ   E +    C +   YLG + + E RG    +DA  +++A  +       
Sbjct: 207 ASTPVQYWQHHPEKLIFQSCDYKAFYLGSMLIKELRGTESTQDACAKMRANCQKST---- 262

Query: 78  KTGKKAVKAVLWVSADGLRVVDEKTKDLIVDQTIEKVSFCAPDRNFDRAFSYICRDGTTR 137
           +  KK    +L VS  G++ +D   K++I +  I  +S  A D      F+YI +D  + 
Sbjct: 263 EQMKKVPTIILSVSYKGVKFIDATNKNIIAEHEIRNISCAAQDPEDLSTFAYITKDLKSN 322

Query: 138 RWICHCFMA 146
              CH F A
Sbjct: 323 HHYCHVFTA 331


>gi|140161500 ankyrin repeat and sterile alpha motif domain containing
            1 [Homo sapiens]
          Length = 1134

 Score = 54.3 bits (129), Expect = 3e-07
 Identities = 31/123 (25%), Positives = 53/123 (43%), Gaps = 8/123 (6%)

Query: 25   WQTDEEGVRTGKCSFPVKYLGHVEVDESRGMHICEDAVKRLKAERKFFKGFFGKTGKKAV 84
            WQ   E +    C +   YLG + + + RG    +DA  +++   +  K        K  
Sbjct: 928  WQHQPEKLIFESCGYEANYLGSMLIKDLRGTESTQDACAKMRKSTEHMK--------KIP 979

Query: 85   KAVLWVSADGLRVVDEKTKDLIVDQTIEKVSFCAPDRNFDRAFSYICRDGTTRRWICHCF 144
              +L ++  G++ +D   K++I +  I  +S  A D      F+YI +D  T    CH F
Sbjct: 980  TIILSITYKGVKFIDASNKNVIAEHEIRNISCAAQDPEDLCTFAYITKDLQTSHHYCHVF 1039

Query: 145  MAV 147
              V
Sbjct: 1040 STV 1042


>gi|19718731 bromodomain-containing protein 4 isoform long [Homo
           sapiens]
          Length = 1362

 Score = 53.1 bits (126), Expect = 7e-07
 Identities = 81/356 (22%), Positives = 128/356 (35%), Gaps = 40/356 (11%)

Query: 200 ATEQAEREEIMKQMQDAKKAETDKIVVGSSVAPGNTAPSPSSPTSPTSDATTS-LEMNNP 258
           A  Q ++ +  K+ +D K+ + +K      V     + +   P   T    +S   ++  
Sbjct: 527 ALSQPQQNKPKKKEKDKKEKKKEKHKRKEEVEENKKSKAKEPPPKKTKKNNSSNSNVSKK 586

Query: 259 HAIPRRHAPIEQLARQGSFRGFPALSQKMSPFKRQLSLRINELPST-------MQRKTDF 311
              P +  P      +   +  P   ++    KRQLSL IN+LP         + +  + 
Sbjct: 587 EPAPMKSKPPPTYESEEEDKCKPMSYEE----KRQLSLDINKLPGEKLGRVVHIIQSREP 642

Query: 312 PIKNAVP-EVEGEAESISSLCSQITNAFSTPEDPFSSAPMTKPVTVVAPQSPT--FQGTE 368
            +KN+ P E+E + E++     +    + T        P  + V V+A  S    F  +E
Sbjct: 643 SLKNSNPDEIEIDFETLKPSTLRELERYVTSCLRKKRKPQAEKVDVIAGSSKMKGFSSSE 702

Query: 369 WGQSSGAASPGLFQAGHRRTPSEADRWL--EEVSKSVRAQQPQASAAPLQPVLQPPPPTA 426
              SS ++S     +     P    +     E  K       Q   AP     QPPPP  
Sbjct: 703 SESSSESSSSDSEDSETEMAPKSKKKGHPGREQKKHHHHHHQQMQQAPAPVPQQPPPPPQ 762

Query: 427 ISQPASPFQGNAFLTSQPVPVGVVPALQPAFVPAQSYPVANGMPYPAPNVPVVGITPSQM 486
              P  P Q       QP P    P++     PA     ++  P+ A  VPV+     Q+
Sbjct: 763 QPPPPPPPQQQ----QQPPPPPPPPSMPQQAAPAMK---SSPPPFIATQVPVL---EPQL 812

Query: 487 VANVFGTAGH--------PQAAHPHQSPSLVRQQTFPHYEASSATTSPFFKPPAQH 534
             +VF   GH        PQ   P   P      T PH    +  +     PPA H
Sbjct: 813 PGSVFDPIGHFTQPILHLPQPELPPHLPQPPEHSTPPHLNQHAVVS-----PPALH 863



 Score = 31.6 bits (70), Expect = 2.2
 Identities = 39/155 (25%), Positives = 50/155 (32%), Gaps = 39/155 (25%)

Query: 370 GQSSGAASPGLFQAGHRRTPSEADRWLEEVSKSVRAQQPQASAAPLQPVLQPPP------ 423
           G+  G    G  + G    P+       + S   + Q PQ +  P+Q    P P      
Sbjct: 178 GRGRGRKETGTAKPGVSTVPNTT-----QASTPPQTQTPQPNPPPVQATPHPFPAVTPDL 232

Query: 424 ----PTAISQPASPFQGNAFLTSQPVPVGVVPALQPAFVPAQSYPVANGMPYPAPNVPVV 479
               P     P  P Q     T  PVP    P   PA  P QS+P            P++
Sbjct: 233 IVQTPVMTVVPPQPLQ-----TPPPVPPQPQPPPAPAPQPVQSHP------------PII 275

Query: 480 GITPSQMVANVFGTAGHPQAAHP------HQSPSL 508
             TP Q V    G         P      H+ PSL
Sbjct: 276 AATP-QPVKTKKGVKRKADTTTPTTIDPIHEPPSL 309



 Score = 30.8 bits (68), Expect = 3.7
 Identities = 54/236 (22%), Positives = 78/236 (33%), Gaps = 27/236 (11%)

Query: 237  PSPSSPTSPTSDATTSLEMNNPHAIPRRHAPIEQLARQGSFRGFPALSQKMSPFKRQLSL 296
            P P  P  P       L+   P   P +  P  Q   Q   R  P   Q M     Q S 
Sbjct: 954  PPPPLPPPPHPSVQQQLQQQPPPPPPPQPQPPPQQQHQPPPR--PVHLQPM-----QFST 1006

Query: 297  RINELPSTMQRKTDFPIKNAVPEVEGEAESISSLCSQITNAFSTPE----DPFSSAPMTK 352
             I + P    ++   P     P     A+       Q+     +P     DP+S+  + +
Sbjct: 1007 HIQQPPPPQGQQPPHPPPGQQPPPPQPAKP-----QQVIQHHHSPRHHKSDPYSTGHLRE 1061

Query: 353  ---PVTVVAPQSPTFQG-TEWGQSSGAASPGLFQAGHRRTPSEADRWLEEVSKSVRAQQP 408
               P+ + +PQ   FQ  T          P   +    R  S        V K  +   P
Sbjct: 1062 APSPLMIHSPQMSQFQSLTHQSPPQQNVQP---KKQELRAASVVQPQPLVVVKEEKIHSP 1118

Query: 409  QASAAPLQPVLQPPPPTAISQPASPFQGNAFLTSQPVPVGVVPALQPAFVPAQSYP 464
               + P  P L+P PP       +P         +PV VG  P ++P   P Q+ P
Sbjct: 1119 IIRSEPFSPSLRPEPPKHPESIKAPVHLPQRPEMKPVDVG-RPVIRP---PEQNAP 1170


>gi|31317301 nitric oxide synthase 1 (neuronal) adaptor protein
           isoform 1 [Homo sapiens]
          Length = 506

 Score = 50.1 bits (118), Expect = 6e-06
 Identities = 65/269 (24%), Positives = 112/269 (41%), Gaps = 46/269 (17%)

Query: 28  DEEGVRTGKCSFPVKYLGHVEVDESRGMHICEDAVKRLKAERKFFKGFFGKTGKKAVKAV 87
           +E+  + G C F  KY+G ++V           A++R++ E      F  K  KK  K  
Sbjct: 22  NEDAFQHGIC-FEAKYVGSLDVPRPNSRVEIVAAMRRIRYE------FKAKNIKKK-KVS 73

Query: 88  LWVSADGLRVVDEKTKDLIVDQTIE----------------KVSFCAPDRNFDRAFSYIC 131
           + VS DG++V+ +K K L++ Q  E                ++ + + D    + FSYI 
Sbjct: 74  IMVSVDGVKVILKKKKKLLLLQKKEWTWDESKMLVMQDPIYRIFYVSHDSQDLKIFSYIA 133

Query: 132 RDGTTRRWICHCFMAVKDT-GERLSHAVGCAFAAC----LERKQKR-------EKECGVT 179
           RDG +  + C+ F + K +   R+   VG AF  C    L+  Q+        E E    
Sbjct: 134 RDGASNIFRCNVFKSKKKSQAMRIVRTVGQAFEVCHKLSLQHTQQNADGQEDGESERNSN 193

Query: 180 ATFDASRTTFTREGSFRVTTAT-EQAEREEIM-----KQMQDAKKAETDKIVVGSSVAPG 233
           ++ D  R      G+ R +TAT E+ + + +        + +  +  TD   VG      
Sbjct: 194 SSGDPGRQL---TGAERASTATAEETDIDAVEVPLPGNDVLEFSRGVTDLDAVGKE-GGS 249

Query: 234 NTAPSPSSPTSPTSDATTSLEMNNPHAIP 262
           +T    S P  P   A+  + + +  + P
Sbjct: 250 HTGSKVSHPQEPMLTASPRMLLPSSSSKP 278


>gi|21327715 transcription elongation regulator 1 isoform 1 [Homo
           sapiens]
          Length = 1098

 Score = 50.1 bits (118), Expect = 6e-06
 Identities = 45/178 (25%), Positives = 71/178 (39%), Gaps = 13/178 (7%)

Query: 316 AVPEVEGEAESISSLCSQITNAFSTPEDPFSSAPMTKPVTVVAPQSPTFQGTEWGQSSGA 375
           A  + + +A+  + + +Q+         P +S+P     T  +  +P+   +    ++  
Sbjct: 233 AQAQAQAQAQVQAQVQAQVQAQAVGASTPTTSSPAPAVSTSTSSSTPSSTTSTTTTATSV 292

Query: 376 ASPGLFQAGHRRTPSEADRWLEEVSKSVRAQQPQASAAPLQPVLQPPPPTAISQPASPFQ 435
           A          +TPS A   +   + +V    P  +A P+Q V QP P T    PA P  
Sbjct: 293 AQTVSTPTTQDQTPSSA---VSVATPTVSVSTPAPTATPVQTVPQPHPQTL--PPAVPH- 346

Query: 436 GNAFLTSQPVPVGVVPALQPAFVPAQSYPVANGMPYPAPNVPVVGITPSQMVANVFGT 493
                 S P P   +PA  P  VP    P+  GMP P P V ++ I     V  V  T
Sbjct: 347 ------SVPQPTTAIPAFPPVMVPPFRVPLP-GMPIPLPGVAMMQIVSCPYVKTVATT 397



 Score = 32.3 bits (72), Expect = 1.3
 Identities = 26/91 (28%), Positives = 37/91 (40%), Gaps = 17/91 (18%)

Query: 405 AQQPQASAAPLQPVLQPPPPTAISQ-----PASPFQGNAF---LTSQPVPVGVVPALQPA 456
           A  P A      P+++PPPP  + +     P  PF    F   +   P P G+ P + P 
Sbjct: 33  APPPNAVMRGPPPLMRPPPPFGMMRGPPPPPRPPFGRPPFDPNMPPMPPPGGIPPPMGPP 92

Query: 457 FV--------PAQSYPVANGMPYPAPNVPVV 479
            +        P  S P   GM +P P +P V
Sbjct: 93  HLQRPPFMPPPMSSMPPPPGMMFP-PGMPPV 122


>gi|149773456 hypothetical protein LOC643314 [Homo sapiens]
          Length = 1427

 Score = 48.9 bits (115), Expect = 1e-05
 Identities = 67/299 (22%), Positives = 110/299 (36%), Gaps = 32/299 (10%)

Query: 231  APGNTAPSPSSPTSPTSDATTSLEMNNPHA-IPRRHAPIEQLARQGSFRGFPALSQKMSP 289
            +P    P+P  PTSP +   T  E  +P A +P    P    A   +    PA      P
Sbjct: 1093 SPAAAVPTPEEPTSPAAAVPTPEEPASPAAAVPTPEEPASPAAAVPTPEE-PAFPAPAVP 1151

Query: 290  FKRQLSLRINELPSTMQRKTDFPIKNAVPEVEGEAESISSLCSQITNAFSTPEDPFSSAP 349
               + +     +P+        P ++A P       + S+  + +      P  P +S P
Sbjct: 1152 TPEESASAAVAVPT--------PEESASPAAAVPTPAESASFAAVVATLEEPTSPAASVP 1203

Query: 350  MTKPVTVVAP----QSPTFQGTEWGQSSGAASPGLFQAGHRRTPSEADRWLEEVSKSVRA 405
               P  +VA      SP        +   + +  +       +P+ A   LEE + S  A
Sbjct: 1204 T--PAAMVATLEEFTSPA-ASVPTSEEPASLAAAVSNPEEPTSPAAAVPTLEEPTSSAAA 1260

Query: 406  Q-QPQASAAPLQPVLQPPPPTAISQPASPFQGNAFLTSQPVPVGVVPALQPAFVPAQSYP 464
               P+  ++P   V  P       +PASP    + L     P   VP  + A +PA S P
Sbjct: 1261 VLTPEELSSPAASVPTP------EEPASPAAAVSNLEEPASPAAAVPTPEVAAIPAASVP 1314

Query: 465  VANGMPYPAPNVPVVGITPSQMVANVFGTAGHPQAAHPHQSPSLVRQQTFPHYEASSAT 523
                     P +P   + P + V+ + G      +AH    P  + ++  P  E +S+T
Sbjct: 1315 TPE-----VPAIPAAAVPPMEEVSPI-GVPFLGVSAHTDSVP--ISEEGTPVLEEASST 1365



 Score = 46.6 bits (109), Expect = 7e-05
 Identities = 62/267 (23%), Positives = 89/267 (33%), Gaps = 24/267 (8%)

Query: 340  TPEDPFSSAPMTKPVTVVAPQSPTFQGTEWGQSSGAASPGLFQAGHRRTPSEADRWLEEV 399
            T ED     P+T   TV AP+ P             ASP    A    TP E        
Sbjct: 965  TEEDGTPEGPVTPATTVHAPEEPDTAAVRVSTPEEPASP----AAAVPTPEEP---TSPA 1017

Query: 400  SKSVRAQQPQASAAPLQPVLQPPPPTAI----SQPASPFQGNAFLTSQPVPVGVVPALQP 455
            +     ++P + AA + P  +P  P A      +P SP            P   VP  + 
Sbjct: 1018 AAVPTPEEPTSPAAAVPPPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEE 1077

Query: 456  AFVPAQSYPVANGMPYPAPNVPVVGITPSQMVANVFGTAGHPQAAHPHQSPSLVRQQTFP 515
               PA + P       PA  VP    TP +  +     A  P    P    + V     P
Sbjct: 1078 PTSPAAAVPTPEEPTSPAAAVP----TPEEPTS---PAAAVPTPEEPASPAAAVPTPEEP 1130

Query: 516  HYEASSATT--SPFFKPPAQHLNGSAAFNGVDDGRLASADRHTEVPTGTCPVDPFEAQWA 573
               A++  T   P F  PA      +A   V           +  P    P     A +A
Sbjct: 1131 ASPAAAVPTPEEPAFPAPAVPTPEESASAAV----AVPTPEESASPAAAVPTPAESASFA 1186

Query: 574  ALENKSKQRTNPSPTNPFSSDLQKTFE 600
            A+    ++ T+P+ + P  + +  T E
Sbjct: 1187 AVVATLEEPTSPAASVPTPAAMVATLE 1213



 Score = 41.6 bits (96), Expect = 0.002
 Identities = 86/360 (23%), Positives = 118/360 (32%), Gaps = 61/360 (16%)

Query: 231  APGNTAPSPSSPTSPTSDATTSLEMNNP-HAIPRRHAPIEQLARQGSFRGFPALSQKMSP 289
            +P    P+P  PTSP +   T  E  +P  A+P    P    A         A+     P
Sbjct: 1002 SPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPPPEEPTSPAA---------AVPTPEEP 1052

Query: 290  FKRQLSLRINELPSTMQRKTDFPIKNAVPEVEGEAESISSLCSQITNAFSTPEDPFSSAP 349
                 ++   E P++       P +   P                  A  TPE+P S A 
Sbjct: 1053 TSPAAAVPTPEEPTSPAAAVPTPEEPTSPAA----------------AVPTPEEPTSPA- 1095

Query: 350  MTKPVTVVAPQSPTFQGTEWGQSSGAASPGLFQAGHRRTPSEADRWLEEVSKSVRAQQPQ 409
                  V  P+ PT            ASP    A    TP       E  S +     P+
Sbjct: 1096 ----AAVPTPEEPTSPAAAVPTPEEPASP----AAAVPTPE------EPASPAAAVPTPE 1141

Query: 410  ASAAPLQPVLQPPPPTAISQPASPFQGNAFLTSQPVPVGVVPALQPAFVPAQSYPVANGM 469
              A P  P +  P  +A +  A P    +   +  VP     A   A V     P +   
Sbjct: 1142 EPAFP-APAVPTPEESASAAVAVPTPEESASPAAAVPTPAESASFAAVVATLEEPTS--- 1197

Query: 470  PYPAPNVPVVGITPSQMVANVFGTAGHPQAAHP--HQSPSLVRQQTFPHYEASSATTSPF 527
              PA +VP    TP+ MVA +      P A+ P   +  SL    + P    S A   P 
Sbjct: 1198 --PAASVP----TPAAMVATLEEFTS-PAASVPTSEEPASLAAAVSNPEEPTSPAAAVPT 1250

Query: 528  FKPPAQHLNGSAAFNGVDDGRLASADRHTEVPTGTCPVDPFEAQWAALENKSKQRTNPSP 587
             + P      S+A   +    L+S      VPT   P  P  A     E  S     P+P
Sbjct: 1251 LEEPT-----SSAAAVLTPEELSSP--AASVPTPEEPASPAAAVSNLEEPASPAAAVPTP 1303


>gi|148491082 disabled homolog 2 [Homo sapiens]
          Length = 770

 Score = 47.8 bits (112), Expect = 3e-05
 Identities = 110/517 (21%), Positives = 191/517 (36%), Gaps = 104/517 (20%)

Query: 39  FPVKYLGHVEVDESRGMHICEDAVKRLKAERKFFKGFFGKTGKKAVKAVLWVSADGLRVV 98
           +  K +G  +V ++RG  + +D++ +LK      +      G+   +  + +S  G++++
Sbjct: 50  YKAKLIGIDDVPDARGDKMSQDSMMKLKGMAAAGRS----QGQHKQRIWVNISLSGIKII 105

Query: 99  DEKTKDLIVDQTIEKVSFCAPDRNFDRAFSYIC-RDGTTRRWICHCFMAVKDTGERLSHA 157
           DEKT  +  +  + K+SF A D   +RAF Y+C  +G       H F A+K TG++    
Sbjct: 106 DEKTGVIEHEHPVNKISFIARDVTDNRAFGYVCGGEGQ------HQFFAIK-TGQQAEPL 158

Query: 158 V---GCAFAACLERKQKREKECGVTATFDASRTTFTREGSFRVTTATEQAEREEIMKQMQ 214
           V      F      K+K E++  +             E S  V   +E      I+    
Sbjct: 159 VVDLKDLFQVIYNVKKKEEEKKKI------------EEASKAVENGSEAL---MILDDQT 203

Query: 215 DAKKAETDKIVVGSSVAPGNTAPSPSSPTSPTSDATTSLEMNNPHAIPRRHAPIEQLARQ 274
           +  K+  D++ +   +   +T P  +SPT   S     +++N+           E    Q
Sbjct: 204 NKLKSGVDQMDLFGDM---STPPDLNSPTE--SKDILLVDLNS-----------EIDTNQ 247

Query: 275 GSFRGFPALSQKMSPFKRQLSLRINELPSTMQRKTDFPIKNAVPEVEGEAESISSLCSQI 334
            S R  P L+  ++               ++ R T  P  + +PE         +  S  
Sbjct: 248 NSLRENPFLTNGIT-------------SCSLPRPT--PQASFLPE---------NAFSAN 283

Query: 335 TNAFSTPE-DPFSSAPMTKPVTVVAPQSPTFQGTEWGQSSGAASPGLFQAGHRRTPSEAD 393
            N F TP  DPF   P T+P         + +  +  + + ++S      G    P   D
Sbjct: 284 LNFFPTPNPDPFRDDPFTQPDQSTPSSFDSLKSPDQKKENSSSSSTPLSNG----PLNGD 339

Query: 394 -----RWLEEVSKSVRAQQPQASAAPLQPVLQPPPPTAISQPASPFQGNAF-LTSQPVP- 446
                +  +++S     Q+ QA   P     Q  P        S  + N F + S P P 
Sbjct: 340 VDYFGQQFDQISNRTGKQEAQAGPWPFSS-SQTQPAVRTQNGVSEREQNGFSVKSSPNPF 398

Query: 447 VGVVPALQPAFVPAQSYPVANGMPYPAPNVPVVGITPSQMVANVFGTAGHPQAAHPHQSP 506
           VG          P +   + NG+     +   V  +P   +A +           P QS 
Sbjct: 399 VG---------SPPKGLSIQNGVKQDLES--SVQSSPHDSIAII----------PPPQST 437

Query: 507 SLVRQQTFPHYEASSATTSPFFKPPAQHLNGSAAFNG 543
              R +      A+    S  F PP    +G A+  G
Sbjct: 438 KPGRGRRTAKSSANDLLASDIFAPPVSEPSGQASPTG 474


>gi|91208418 transcription elongation regulator 1 isoform 2 [Homo
           sapiens]
          Length = 1077

 Score = 47.8 bits (112), Expect = 3e-05
 Identities = 43/168 (25%), Positives = 69/168 (41%), Gaps = 14/168 (8%)

Query: 316 AVPEVEGEAESISSLCSQITNAFSTPEDPFSSAPMTKPVTVVAPQSPTFQGTEWGQSSGA 375
           A  + + +A+  + + +Q+         P +S+P     T  +  +P+   +    ++  
Sbjct: 233 AQAQAQAQAQVQAQVQAQVQAQAVGASTPTTSSPAPAVSTSTSSSTPSSTTSTTTTATSV 292

Query: 376 ASPGLFQAGHRRTPSEADRWLEEVSKSVRAQQPQASAAPLQPVLQPPPPTAISQPASPFQ 435
           A          +TPS A   +   + +V    P  +A P+Q V QP P T    PA P  
Sbjct: 293 AQTVSTPTTQDQTPSSA---VSVATPTVSVSTPAPTATPVQTVPQPHPQTL--PPAVPH- 346

Query: 436 GNAFLTSQPVPVGVVPALQPAFVPAQSYPVANGMPYPAPNVPVVGITP 483
                 S P P   +PA  P  VP    P+  GMP P P V + G+ P
Sbjct: 347 ------SVPQPTTAIPAFPPVMVPPFRVPLP-GMPIPLPGV-LPGMAP 386



 Score = 32.3 bits (72), Expect = 1.3
 Identities = 26/91 (28%), Positives = 37/91 (40%), Gaps = 17/91 (18%)

Query: 405 AQQPQASAAPLQPVLQPPPPTAISQ-----PASPFQGNAF---LTSQPVPVGVVPALQPA 456
           A  P A      P+++PPPP  + +     P  PF    F   +   P P G+ P + P 
Sbjct: 33  APPPNAVMRGPPPLMRPPPPFGMMRGPPPPPRPPFGRPPFDPNMPPMPPPGGIPPPMGPP 92

Query: 457 FV--------PAQSYPVANGMPYPAPNVPVV 479
            +        P  S P   GM +P P +P V
Sbjct: 93  HLQRPPFMPPPMSSMPPPPGMMFP-PGMPPV 122


>gi|153792074 proline rich 12 [Homo sapiens]
          Length = 2036

 Score = 47.8 bits (112), Expect = 3e-05
 Identities = 63/251 (25%), Positives = 88/251 (35%), Gaps = 24/251 (9%)

Query: 232  PGNTAPS-PSSPTSPTSDATTSLEMNNPHAIPRRHAPIEQLARQGSFRGFPALSQKMSPF 290
            P +  PS P+    P   AT ++    P         +E    +G   G P+  +++   
Sbjct: 1310 PKSVPPSVPARGLQPQPPATPAVPHPPPSGAFGLGGALEAAESEGLGLGCPSPCKRLD-- 1367

Query: 291  KRQLSLRINELPSTMQRKTDFPIKNAVPEVEGEAESISSLCSQITNA-FSTPEDPFSSAP 349
              +L   +  LPS    + D   KN   +     ESISS  S + +   + P+D  +S P
Sbjct: 1368 -EELKRNLETLPSFSSDEEDSVAKNRDLQ-----ESISSAISALDDPPLAGPKD--TSTP 1419

Query: 350  MTKPVTVVA--PQSPTFQGTEWGQSSGAASPGLFQAGHRRTPSEADRWLEEVSKSVRAQQ 407
               P+   A  P  P   G     S+G   P L +     TP  A              Q
Sbjct: 1420 DGPPLAPAAAVPGPPPLPGLPSANSNGTPEPPLLEEKPPPTPPPAP---------TPQPQ 1470

Query: 408  PQASAAPLQPVLQPPPPTAISQPASPFQGNAFLTSQPVPVGVVPALQPAFVPAQSYPVAN 467
            P     P QP L  PPP     P+SP          P      P   PA  P  + P   
Sbjct: 1471 PPPPPPPPQPALPSPPPLVAPTPSSPPPPPLPPPPPPAMPSPPPPPPPAAAPLAAPPEEP 1530

Query: 468  GMPYPA-PNVP 477
              P P  P +P
Sbjct: 1531 AAPSPEDPELP 1541



 Score = 33.5 bits (75), Expect = 0.58
 Identities = 46/158 (29%), Positives = 61/158 (38%), Gaps = 21/158 (13%)

Query: 405 AQQPQASAAPLQPVLQPPPP-TAISQPASP--FQGNAF-LTSQPVPVGVVPALQ--PAFV 458
           ++ P  S  P QP   PPPP  A  Q  SP   QG  + +  +P P G     Q  P   
Sbjct: 470 SKAPSYSGGPPQPPSGPPPPGLATCQSYSPDQLQGQLYGVQGEPYP-GPAAHSQGLPTAS 528

Query: 459 PAQSYPVANGMPYPAPNVPVVGITPSQMVANVFGTAGHPQAAHPHQSPSL------VRQQ 512
           P+ SY   +    PA +    G  PS +     G A       P QSP        V   
Sbjct: 529 PSLSYSTGHS---PALSGHGGGWGPSSLGGG--GEASPSHIIRPLQSPPATGRPPGVGSP 583

Query: 513 TFP-HYEASSATTSPFFKPP--AQHLNGSAAFNGVDDG 547
             P  Y +S   ++PF  PP    +  G+  + G  DG
Sbjct: 584 GAPGKYLSSVLASAPFLAPPGAGSYAAGAGGYKGKGDG 621


>gi|189181724 proteoglycan 4 isoform D [Homo sapiens]
          Length = 1270

 Score = 47.0 bits (110), Expect = 5e-05
 Identities = 90/426 (21%), Positives = 141/426 (33%), Gaps = 50/426 (11%)

Query: 179 TATFDASRTTFTREG-SFRVTTATEQAEREEIMKQMQDAKKAETDKIVVGSSVAPGNTAP 237
           T+T    +TT  +E  S   T+A + A   +++ +     KAET      ++  P  T P
Sbjct: 162 TSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAK--PTPKAET------TTKGPALTTP 213

Query: 238 SPSSPTSPTSDATTSLEMNNPHAI------PRRHAPIE-QLARQGSFRGFPALSQKMSPF 290
              +PT+P   A+T+ +   P  I      P+  AP   + A        P  +++ +P 
Sbjct: 214 KEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPT 273

Query: 291 --KRQLSLRINE-LPSTMQRKTDFPIKNAVPEVEGEAESISSLCSQITNAFSTPEDPFSS 347
             K        E  P+T +     P + A    +  A +     +  T    TP  P   
Sbjct: 274 TPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEP 333

Query: 348 APMTKPVTVVAPQSPTFQGTEWGQSSGAASPGLFQAGHRRTPSEADRWLEEVSKSVRAQQ 407
           AP TK      P+ P     +    +    P         TP E      +       ++
Sbjct: 334 APTTKEPAPTTPKEPAPTAPKKPAPTTPKEPA------PTTPKEPAPTTTKEPSPTTPKE 387

Query: 408 PQASAAPLQPVL--QPPPPTAISQPASPFQGNAFLTSQPVPVGVVPALQPAFVPAQSYPV 465
           P  +     P    +P P T  S P +P + +   T +P P            P +  P 
Sbjct: 388 PAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPT----------TPKEPAPT 437

Query: 466 ANGMPYPAPNVPVVGITPSQMVANVFGTAGHPQAAHPHQSPSLVRQQTFPHYEASSATTS 525
               P P         TP +       T   P    P +      ++T P        T+
Sbjct: 438 TPKKPAPTTPKEPAPTTPKEPAPT---TTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTT 494

Query: 526 PFFKPPAQHLNGSAAFNGVDDGRLASADRHTEVPTGTCPVDPF-EAQWAALENKSKQRTN 584
           P      + L  +             A    E PT T P +P      AA  N  K+   
Sbjct: 495 P------EKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKE--- 545

Query: 585 PSPTNP 590
           P+PT P
Sbjct: 546 PAPTTP 551



 Score = 36.2 bits (82), Expect = 0.089
 Identities = 51/247 (20%), Positives = 81/247 (32%), Gaps = 32/247 (12%)

Query: 232 PGNTAPSPSSPTSPTSDATTSLEMNNPHAIPRRHAPIEQLARQGSFRGFPALSQKMSPFK 291
           P  T P   +PT+P   A T+         P+  AP        +    PA +    P  
Sbjct: 546 PAPTTPKEPAPTTPKEPAPTT---------PKETAPTTPKGTAPTTLKEPAPTTPKKPAP 596

Query: 292 RQLSLRINELPSTMQRKTDFPIKNAVPEV-EGEAESISSLCSQITNAFSTPEDPFSSAPM 350
           ++L+      P+T +  T        P   +G A +     +  T     P  P  +AP 
Sbjct: 597 KELA------PTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPT 650

Query: 351 T-KPVTVVAPQSPTFQGTEWGQSSGAASPGLFQAGHRRTPSEADRWLEEVSKSVRAQQPQ 409
           T K      P+ P  +      + G  S        +  P+          K      P+
Sbjct: 651 TLKEPAPTTPKKPAPKELAPTTTKGPTS----TTSDKPAPTTPKETAPTTPKEPAPTTPK 706

Query: 410 ASAAPLQPVLQPPPPTAISQPA----------SPFQGNAFLTSQPVPVGVVPALQPAFVP 459
              AP  P   PP  + +S P           SP +    L+++P P  +  + +   VP
Sbjct: 707 -KPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEPGVP 765

Query: 460 AQSYPVA 466
               P A
Sbjct: 766 TTKTPAA 772


>gi|189181722 proteoglycan 4 isoform C [Homo sapiens]
          Length = 1311

 Score = 47.0 bits (110), Expect = 5e-05
 Identities = 90/426 (21%), Positives = 141/426 (33%), Gaps = 50/426 (11%)

Query: 179 TATFDASRTTFTREG-SFRVTTATEQAEREEIMKQMQDAKKAETDKIVVGSSVAPGNTAP 237
           T+T    +TT  +E  S   T+A + A   +++ +     KAET      ++  P  T P
Sbjct: 203 TSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAK--PTPKAET------TTKGPALTTP 254

Query: 238 SPSSPTSPTSDATTSLEMNNPHAI------PRRHAPIE-QLARQGSFRGFPALSQKMSPF 290
              +PT+P   A+T+ +   P  I      P+  AP   + A        P  +++ +P 
Sbjct: 255 KEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPT 314

Query: 291 --KRQLSLRINE-LPSTMQRKTDFPIKNAVPEVEGEAESISSLCSQITNAFSTPEDPFSS 347
             K        E  P+T +     P + A    +  A +     +  T    TP  P   
Sbjct: 315 TPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEP 374

Query: 348 APMTKPVTVVAPQSPTFQGTEWGQSSGAASPGLFQAGHRRTPSEADRWLEEVSKSVRAQQ 407
           AP TK      P+ P     +    +    P         TP E      +       ++
Sbjct: 375 APTTKEPAPTTPKEPAPTAPKKPAPTTPKEPA------PTTPKEPAPTTTKEPSPTTPKE 428

Query: 408 PQASAAPLQPVL--QPPPPTAISQPASPFQGNAFLTSQPVPVGVVPALQPAFVPAQSYPV 465
           P  +     P    +P P T  S P +P + +   T +P P            P +  P 
Sbjct: 429 PAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPT----------TPKEPAPT 478

Query: 466 ANGMPYPAPNVPVVGITPSQMVANVFGTAGHPQAAHPHQSPSLVRQQTFPHYEASSATTS 525
               P P         TP +       T   P    P +      ++T P        T+
Sbjct: 479 TPKKPAPTTPKEPAPTTPKEPAPT---TTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTT 535

Query: 526 PFFKPPAQHLNGSAAFNGVDDGRLASADRHTEVPTGTCPVDPF-EAQWAALENKSKQRTN 584
           P      + L  +             A    E PT T P +P      AA  N  K+   
Sbjct: 536 P------EKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKE--- 586

Query: 585 PSPTNP 590
           P+PT P
Sbjct: 587 PAPTTP 592



 Score = 36.2 bits (82), Expect = 0.089
 Identities = 51/247 (20%), Positives = 81/247 (32%), Gaps = 32/247 (12%)

Query: 232 PGNTAPSPSSPTSPTSDATTSLEMNNPHAIPRRHAPIEQLARQGSFRGFPALSQKMSPFK 291
           P  T P   +PT+P   A T+         P+  AP        +    PA +    P  
Sbjct: 587 PAPTTPKEPAPTTPKEPAPTT---------PKETAPTTPKGTAPTTLKEPAPTTPKKPAP 637

Query: 292 RQLSLRINELPSTMQRKTDFPIKNAVPEV-EGEAESISSLCSQITNAFSTPEDPFSSAPM 350
           ++L+      P+T +  T        P   +G A +     +  T     P  P  +AP 
Sbjct: 638 KELA------PTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPT 691

Query: 351 T-KPVTVVAPQSPTFQGTEWGQSSGAASPGLFQAGHRRTPSEADRWLEEVSKSVRAQQPQ 409
           T K      P+ P  +      + G  S        +  P+          K      P+
Sbjct: 692 TLKEPAPTTPKKPAPKELAPTTTKGPTS----TTSDKPAPTTPKETAPTTPKEPAPTTPK 747

Query: 410 ASAAPLQPVLQPPPPTAISQPA----------SPFQGNAFLTSQPVPVGVVPALQPAFVP 459
              AP  P   PP  + +S P           SP +    L+++P P  +  + +   VP
Sbjct: 748 -KPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEPGVP 806

Query: 460 AQSYPVA 466
               P A
Sbjct: 807 TTKTPAA 813


>gi|189181720 proteoglycan 4 isoform B [Homo sapiens]
          Length = 1363

 Score = 47.0 bits (110), Expect = 5e-05
 Identities = 90/426 (21%), Positives = 141/426 (33%), Gaps = 50/426 (11%)

Query: 179 TATFDASRTTFTREG-SFRVTTATEQAEREEIMKQMQDAKKAETDKIVVGSSVAPGNTAP 237
           T+T    +TT  +E  S   T+A + A   +++ +     KAET      ++  P  T P
Sbjct: 255 TSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAK--PTPKAET------TTKGPALTTP 306

Query: 238 SPSSPTSPTSDATTSLEMNNPHAI------PRRHAPIE-QLARQGSFRGFPALSQKMSPF 290
              +PT+P   A+T+ +   P  I      P+  AP   + A        P  +++ +P 
Sbjct: 307 KEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPT 366

Query: 291 --KRQLSLRINE-LPSTMQRKTDFPIKNAVPEVEGEAESISSLCSQITNAFSTPEDPFSS 347
             K        E  P+T +     P + A    +  A +     +  T    TP  P   
Sbjct: 367 TPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEP 426

Query: 348 APMTKPVTVVAPQSPTFQGTEWGQSSGAASPGLFQAGHRRTPSEADRWLEEVSKSVRAQQ 407
           AP TK      P+ P     +    +    P         TP E      +       ++
Sbjct: 427 APTTKEPAPTTPKEPAPTAPKKPAPTTPKEPA------PTTPKEPAPTTTKEPSPTTPKE 480

Query: 408 PQASAAPLQPVL--QPPPPTAISQPASPFQGNAFLTSQPVPVGVVPALQPAFVPAQSYPV 465
           P  +     P    +P P T  S P +P + +   T +P P            P +  P 
Sbjct: 481 PAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPT----------TPKEPAPT 530

Query: 466 ANGMPYPAPNVPVVGITPSQMVANVFGTAGHPQAAHPHQSPSLVRQQTFPHYEASSATTS 525
               P P         TP +       T   P    P +      ++T P        T+
Sbjct: 531 TPKKPAPTTPKEPAPTTPKEPAPT---TTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTT 587

Query: 526 PFFKPPAQHLNGSAAFNGVDDGRLASADRHTEVPTGTCPVDPF-EAQWAALENKSKQRTN 584
           P      + L  +             A    E PT T P +P      AA  N  K+   
Sbjct: 588 P------EKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKE--- 638

Query: 585 PSPTNP 590
           P+PT P
Sbjct: 639 PAPTTP 644



 Score = 36.2 bits (82), Expect = 0.089
 Identities = 51/247 (20%), Positives = 81/247 (32%), Gaps = 32/247 (12%)

Query: 232 PGNTAPSPSSPTSPTSDATTSLEMNNPHAIPRRHAPIEQLARQGSFRGFPALSQKMSPFK 291
           P  T P   +PT+P   A T+         P+  AP        +    PA +    P  
Sbjct: 639 PAPTTPKEPAPTTPKEPAPTT---------PKETAPTTPKGTAPTTLKEPAPTTPKKPAP 689

Query: 292 RQLSLRINELPSTMQRKTDFPIKNAVPEV-EGEAESISSLCSQITNAFSTPEDPFSSAPM 350
           ++L+      P+T +  T        P   +G A +     +  T     P  P  +AP 
Sbjct: 690 KELA------PTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPT 743

Query: 351 T-KPVTVVAPQSPTFQGTEWGQSSGAASPGLFQAGHRRTPSEADRWLEEVSKSVRAQQPQ 409
           T K      P+ P  +      + G  S        +  P+          K      P+
Sbjct: 744 TLKEPAPTTPKKPAPKELAPTTTKGPTS----TTSDKPAPTTPKETAPTTPKEPAPTTPK 799

Query: 410 ASAAPLQPVLQPPPPTAISQPA----------SPFQGNAFLTSQPVPVGVVPALQPAFVP 459
              AP  P   PP  + +S P           SP +    L+++P P  +  + +   VP
Sbjct: 800 -KPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEPGVP 858

Query: 460 AQSYPVA 466
               P A
Sbjct: 859 TTKTPAA 865


>gi|67190163 proteoglycan 4 isoform A [Homo sapiens]
          Length = 1404

 Score = 47.0 bits (110), Expect = 5e-05
 Identities = 90/426 (21%), Positives = 141/426 (33%), Gaps = 50/426 (11%)

Query: 179 TATFDASRTTFTREG-SFRVTTATEQAEREEIMKQMQDAKKAETDKIVVGSSVAPGNTAP 237
           T+T    +TT  +E  S   T+A + A   +++ +     KAET      ++  P  T P
Sbjct: 296 TSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAK--PTPKAET------TTKGPALTTP 347

Query: 238 SPSSPTSPTSDATTSLEMNNPHAI------PRRHAPIE-QLARQGSFRGFPALSQKMSPF 290
              +PT+P   A+T+ +   P  I      P+  AP   + A        P  +++ +P 
Sbjct: 348 KEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPT 407

Query: 291 --KRQLSLRINE-LPSTMQRKTDFPIKNAVPEVEGEAESISSLCSQITNAFSTPEDPFSS 347
             K        E  P+T +     P + A    +  A +     +  T    TP  P   
Sbjct: 408 TPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEP 467

Query: 348 APMTKPVTVVAPQSPTFQGTEWGQSSGAASPGLFQAGHRRTPSEADRWLEEVSKSVRAQQ 407
           AP TK      P+ P     +    +    P         TP E      +       ++
Sbjct: 468 APTTKEPAPTTPKEPAPTAPKKPAPTTPKEPA------PTTPKEPAPTTTKEPSPTTPKE 521

Query: 408 PQASAAPLQPVL--QPPPPTAISQPASPFQGNAFLTSQPVPVGVVPALQPAFVPAQSYPV 465
           P  +     P    +P P T  S P +P + +   T +P P            P +  P 
Sbjct: 522 PAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPT----------TPKEPAPT 571

Query: 466 ANGMPYPAPNVPVVGITPSQMVANVFGTAGHPQAAHPHQSPSLVRQQTFPHYEASSATTS 525
               P P         TP +       T   P    P +      ++T P        T+
Sbjct: 572 TPKKPAPTTPKEPAPTTPKEPAPT---TTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTT 628

Query: 526 PFFKPPAQHLNGSAAFNGVDDGRLASADRHTEVPTGTCPVDPF-EAQWAALENKSKQRTN 584
           P      + L  +             A    E PT T P +P      AA  N  K+   
Sbjct: 629 P------EKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKE--- 679

Query: 585 PSPTNP 590
           P+PT P
Sbjct: 680 PAPTTP 685



 Score = 36.2 bits (82), Expect = 0.089
 Identities = 51/247 (20%), Positives = 81/247 (32%), Gaps = 32/247 (12%)

Query: 232 PGNTAPSPSSPTSPTSDATTSLEMNNPHAIPRRHAPIEQLARQGSFRGFPALSQKMSPFK 291
           P  T P   +PT+P   A T+         P+  AP        +    PA +    P  
Sbjct: 680 PAPTTPKEPAPTTPKEPAPTT---------PKETAPTTPKGTAPTTLKEPAPTTPKKPAP 730

Query: 292 RQLSLRINELPSTMQRKTDFPIKNAVPEV-EGEAESISSLCSQITNAFSTPEDPFSSAPM 350
           ++L+      P+T +  T        P   +G A +     +  T     P  P  +AP 
Sbjct: 731 KELA------PTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPT 784

Query: 351 T-KPVTVVAPQSPTFQGTEWGQSSGAASPGLFQAGHRRTPSEADRWLEEVSKSVRAQQPQ 409
           T K      P+ P  +      + G  S        +  P+          K      P+
Sbjct: 785 TLKEPAPTTPKKPAPKELAPTTTKGPTS----TTSDKPAPTTPKETAPTTPKEPAPTTPK 840

Query: 410 ASAAPLQPVLQPPPPTAISQPA----------SPFQGNAFLTSQPVPVGVVPALQPAFVP 459
              AP  P   PP  + +S P           SP +    L+++P P  +  + +   VP
Sbjct: 841 -KPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEPGVP 899

Query: 460 AQSYPVA 466
               P A
Sbjct: 900 TTKTPAA 906


>gi|146219843 Snf2-related CBP activator protein [Homo sapiens]
          Length = 3230

 Score = 46.6 bits (109), Expect = 7e-05
 Identities = 93/387 (24%), Positives = 144/387 (37%), Gaps = 74/387 (19%)

Query: 235  TAPSPSS-PTSPTSDATTSLEMNNPHAIPRRHAPIEQLARQGSFRGFPALSQK-MSPFKR 292
            T P+P+S P +    A  ++  + P  +     P+  +       G P+L+    SP   
Sbjct: 1446 TLPAPASAPLTIPISAPLTVSASGPALLTSVTPPLAPVVPAAP--GPPSLAPSGASPSAS 1503

Query: 293  QLSLRINELPSTMQRKTD------FPIKNAVPEVEGEAESISSLCSQITNAFSTPEDPFS 346
             L+L +   PS    +T        P  + VP   G   +++  CS +    S    PF 
Sbjct: 1504 ALTLGLATAPSLSSSQTPGHPLLLAPTSSHVP---GLNSTVAPACSPVLVPASALASPFP 1560

Query: 347  SAPMTKP--VTVVAPQSPTFQGTEWGQSSGAASPGLFQAGHRRTPSEADRWLEEVSKSVR 404
            SAP   P   +++AP S          S   A+P          P  A +       ++ 
Sbjct: 1561 SAPNPAPAQASLLAPAS--------SASQALATP--------LAPMAAPQ------TAIL 1598

Query: 405  AQQPQASAAPLQPVLQPPP-----------PTAISQPASPFQGNAFLTSQPVPVG---VV 450
            A  P    APL PVL P P           P  +  P+S   G +  ++ PVP     + 
Sbjct: 1599 APSPAPPLAPL-PVLAPSPGAAPVLASSQTPVPVMAPSST-PGTSLASASPVPAPTPVLA 1656

Query: 451  PALQPAFVPAQSYPVANGMPYPAPNVPVV----------GITPSQMVANVFGTAGHPQAA 500
            P+     +PA   PV + +P PA    +           G +PSQ ++   GT G+PQ  
Sbjct: 1657 PSSTQTMLPA---PVPSPLPSPASTQTLALAPALAPTLGGSSPSQTLS--LGT-GNPQGP 1710

Query: 501  HPHQSPSLVRQQTFPHYEASSATTSPFFKPPAQHLNGSAAFNGVDDGRLASADRHTEVPT 560
             P Q+ SL    +     A + + +P   PP   L  +   +      LA A      P 
Sbjct: 1711 FPTQTLSLTPASSLVPTPAQTLSLAP--GPP---LGPTQTLSLAPAPPLAPASPVGPAPA 1765

Query: 561  GTCPVDPFEAQWAALENKSKQRTNPSP 587
             T  + P  +  + L   S Q    SP
Sbjct: 1766 HTLTLAPASSSASLLAPASVQTLTLSP 1792


>gi|91208420 bassoon protein [Homo sapiens]
          Length = 3926

 Score = 45.4 bits (106), Expect = 1e-04
 Identities = 45/180 (25%), Positives = 66/180 (36%), Gaps = 11/180 (6%)

Query: 408  PQASAAPLQPVLQPPPPTAISQPASPFQGNAFLTSQPVPVGVVPALQPAFVPAQSYPVAN 467
            P    A  QP  QPP P   +    P Q        P   G      PAF P  SYP   
Sbjct: 3045 PSGPTAFQQPRFQPPAPQYSAGSGGPTQNGFPAHQAPTYPGPSTYPAPAFPPGASYPAEP 3104

Query: 468  GMPYP---APNVPVVGITPSQMV-ANVFGTAGHPQA--AHPHQSPSLVRQQTFP-HYEAS 520
            G+P      P     G TP     + +F      +A    P Q+     +Q  P +YE  
Sbjct: 3105 GLPNQQAFRPTGHYAGQTPMPTTQSTLFPVPADSRAPLQKPRQTSLADLEQKVPTNYEVI 3164

Query: 521  SATTSPFFKPPAQ-HLNGSAAFNGVDDGRLASADR---HTEVPTGTCPVDPFEAQWAALE 576
            ++   P    P++   +G A  +G + G++    R      V     P  P ++ + +LE
Sbjct: 3165 ASPVVPMSSAPSETSYSGPAVSSGYEQGKVPEVPRAGDRGSVSQSPAPTYPSDSHYTSLE 3224



 Score = 30.4 bits (67), Expect = 4.9
 Identities = 80/331 (24%), Positives = 117/331 (35%), Gaps = 59/331 (17%)

Query: 191  REGSFRVTTATEQAEREEIMKQMQDAKKAETDKIVV-GSSVAPGNTAPSPSSPTSPTSDA 249
            R+ S R     E  ++E   KQ  +A+ A  D +   G  + PG    SP+   +P S +
Sbjct: 1271 RQASSRDLAFAEDKKKE---KQFLNAESAYMDPMKQNGGPLTPGT---SPTQLAAPVSFS 1324

Query: 250  T-TSLEMNNPHAIPRRHAPIEQLARQGSFRGFPALSQKMSPFK--RQLSLRINELPSTMQ 306
            T TS + +    IP     + Q   + +       S   SP    +++ +  ++ P T  
Sbjct: 1325 TPTSSDSSGGRVIP--DVRVTQHFAKETQDPLKLHSSPASPSSASKEIGMPFSQGPGTPA 1382

Query: 307  RKTDFPIKNAVPEVEGEAESISSLCSQITNAFSTPEDPFSSAPMTKPV---TVVAPQSPT 363
                 P    +P   G     S   S+ + + S+    +  +P T      T   PQ+P 
Sbjct: 1383 TTAVAPCPAGLPR--GYMTPASPAGSERSPSPSSTAHSYGHSPTTANYGSQTEDLPQAP- 1439

Query: 364  FQGTEWGQSSGAASPGLFQAGHRRTPSEADRWLEEVSKSVRAQQPQASAAP-LQPVLQPP 422
                     SG A+ G      R  P  A        +  RA    AS++P L P     
Sbjct: 1440 ---------SGLAAAG---RAAREKPLSASDGEGGTPQPSRAYSYFASSSPPLSPSSPSE 1487

Query: 423  PPTAISQPASPFQGNAFLTSQPVPVGVVPALQPAFVPAQSYPVANGMPYPAPNVPVVGIT 482
             PT       P     F T  P P            PA   P + G P           T
Sbjct: 1488 SPTFSPGKMGPRATAEFSTQTPSPA-----------PASDMPRSPGAP-----------T 1525

Query: 483  PSQMVANVFGTAGHPQAAHPHQSPSLVRQQT 513
            PS MVA   GT    Q  H   +P LV Q++
Sbjct: 1526 PSPMVAQ--GT----QTPHRPSTPRLVWQES 1550


>gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo
           sapiens]
          Length = 855

 Score = 45.1 bits (105), Expect = 2e-04
 Identities = 75/309 (24%), Positives = 108/309 (34%), Gaps = 43/309 (13%)

Query: 226 VGSSVAPGNTAPSPSSPTSPTSDATTSLEMNNPHAIPRRHAPIEQLARQG-SFRGFPALS 284
           V S+     T PSP++   P++     L+     ++     P+   AR G S RG P   
Sbjct: 209 VSSASEHSTTEPSPAARRRPSAGG--GLQRPASRSLSSSATPLSSPARSGPSARGTPRAP 266

Query: 285 QKMSPFKRQLSLRINELPSTMQRK---------TDFPIKNAVPEVEGEAESISSL----- 330
              S  K +    +     T  RK         +  P+    P    ++++  +L     
Sbjct: 267 AHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAALQSQAPPTLPATPH 326

Query: 331 CSQITNAFSTP---EDPFSSAPMTKPVTVVAPQSPTFQGTEWGQSSGAASPGLFQAGHRR 387
            S +T   +TP     P  SAP +       P +P  Q T     +   SP L QA H  
Sbjct: 327 SSSLTCQLATPLPLAPPSPSAPPSLQTLPSPPATPPSQAT-----TSLGSPTL-QATHSF 380

Query: 388 TPSEADRWLEEVSKSVRAQQPQASAAPLQPVLQPPP---------PTAISQPASPFQGNA 438
            PS            +    PQA  A   P LQ PP         P A   P +P     
Sbjct: 381 LPSPP-------LSPLATPPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNALAV 433

Query: 439 FLTSQPVPVGVVPALQPAFVPAQSYPVANGMPYPAPNVPVVGITPSQMVANVFGTAG-HP 497
            L   P      P +Q  F P  S PV+     P+   P +   P Q+  +   +    P
Sbjct: 434 HLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSP 493

Query: 498 QAAHPHQSP 506
            A  P Q+P
Sbjct: 494 SATPPPQAP 502



 Score = 34.3 bits (77), Expect = 0.34
 Identities = 78/329 (23%), Positives = 114/329 (34%), Gaps = 56/329 (17%)

Query: 228 SSVAPGNTAPSPSSPTSPTSDATTSLEMNNPHAIPRRHAPIEQLARQGSFRGFPALSQKM 287
           S  AP +    PS P +P S ATTSL            +P  Q     SF   P LS   
Sbjct: 344 SPSAPPSLQTLPSPPATPPSQATTSLG-----------SPTLQATH--SFLPSPPLSPLA 390

Query: 288 SPFKRQL-SLRINELPSTMQRKTDFPIKNAVPEVEGEAESISSLCSQITNA-FSTPEDPF 345
           +P  +   +L +  L +        P+    P      ++ ++L   +  A FS P  P 
Sbjct: 391 TPPPQAPPALALPPLQAPPSPPASPPLS---PLATPSPQAPNALAVHLLQAPFSPPPSPP 447

Query: 346 SSAPMTKPVTVVAPQSPTFQGTEWGQSSGAASPGLFQAGHRRTPSEADRWLEEVSKSVRA 405
             AP + P +   P SP+         S AA P                   +V  S  A
Sbjct: 448 VQAPFSPPAS--PPVSPSATPPSQAPPSLAAPP------------------LQVPPSPPA 487

Query: 406 QQPQASAAPLQPVLQPPPPTAISQPASPFQGNAFLTSQPVPVGVVPALQPAFVPAQSYPV 465
             P + +A        PPP A    A+P    A    Q  P    P LQ    P  S+P 
Sbjct: 488 SPPMSPSAT-------PPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFP- 539

Query: 466 ANGMPY-PAPNVPVVGI-TPSQMVANVFGTAGHPQAAHPHQSPSLVRQQTFPHYEASSAT 523
               P+ P+ ++P+  + TP      V           P  SP+L   +  P     ++ 
Sbjct: 540 -GQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSV 598

Query: 524 TSPFF-------KPPAQHLNGSAAFNGVD 545
           + P          PP    + S+  +G D
Sbjct: 599 SGPRLTLALAPGPPPPPSRSPSSTLSGPD 627


>gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo
           sapiens]
          Length = 816

 Score = 45.1 bits (105), Expect = 2e-04
 Identities = 73/292 (25%), Positives = 101/292 (34%), Gaps = 39/292 (13%)

Query: 226 VGSSVAPGNTAPSPSSPTSPTSDATTSLEMNNPHAIPRRHAPIEQLARQG-SFRGFPALS 284
           V S+     T PSP++   P++     L+     ++     P+   AR G S RG P   
Sbjct: 200 VSSASEHSTTEPSPAARRRPSAGG--GLQRPASRSLSSSATPLSSPARSGPSARGTPRAP 257

Query: 285 QKMSPFKRQLSLRINELPSTMQRKTDFPIKNAVPEVEGEAESISSLCSQITNAFSTPEDP 344
              S  K +       L +    +   P K+A P       ++  L S      S    P
Sbjct: 258 AHPSQPKPK------GLQALRPPQVTPPRKDAAP-------ALGPLSSSPLATPSPSAPP 304

Query: 345 FSSAPMTKPVTVVAPQSPTFQGTEWGQSSGAASPGLFQAGHRRTPSEADRWLEEVSKSVR 404
             SAP +       P +P  Q T     +   SP L QA H   PS            + 
Sbjct: 305 SPSAPPSLQTLPSPPATPPSQAT-----TSLGSPTL-QATHSFLPSPP-------LSPLA 351

Query: 405 AQQPQASAAPLQPVLQPPP---------PTAISQPASPFQGNAFLTSQPVPVGVVPALQP 455
              PQA  A   P LQ PP         P A   P +P      L   P      P +Q 
Sbjct: 352 TPPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQA 411

Query: 456 AFVPAQSYPVANGMPYPAPNVPVVGITPSQMVANVFGTAG-HPQAAHPHQSP 506
            F P  S PV+     P+   P +   P Q+  +   +    P A  P Q+P
Sbjct: 412 PFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAP 463



 Score = 34.3 bits (77), Expect = 0.34
 Identities = 78/329 (23%), Positives = 114/329 (34%), Gaps = 56/329 (17%)

Query: 228 SSVAPGNTAPSPSSPTSPTSDATTSLEMNNPHAIPRRHAPIEQLARQGSFRGFPALSQKM 287
           S  AP +    PS P +P S ATTSL            +P  Q     SF   P LS   
Sbjct: 305 SPSAPPSLQTLPSPPATPPSQATTSLG-----------SPTLQATH--SFLPSPPLSPLA 351

Query: 288 SPFKRQL-SLRINELPSTMQRKTDFPIKNAVPEVEGEAESISSLCSQITNA-FSTPEDPF 345
           +P  +   +L +  L +        P+    P      ++ ++L   +  A FS P  P 
Sbjct: 352 TPPPQAPPALALPPLQAPPSPPASPPLS---PLATPSPQAPNALAVHLLQAPFSPPPSPP 408

Query: 346 SSAPMTKPVTVVAPQSPTFQGTEWGQSSGAASPGLFQAGHRRTPSEADRWLEEVSKSVRA 405
             AP + P +   P SP+         S AA P                   +V  S  A
Sbjct: 409 VQAPFSPPAS--PPVSPSATPPSQAPPSLAAPP------------------LQVPPSPPA 448

Query: 406 QQPQASAAPLQPVLQPPPPTAISQPASPFQGNAFLTSQPVPVGVVPALQPAFVPAQSYPV 465
             P + +A        PPP A    A+P    A    Q  P    P LQ    P  S+P 
Sbjct: 449 SPPMSPSAT-------PPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFP- 500

Query: 466 ANGMPY-PAPNVPVVGI-TPSQMVANVFGTAGHPQAAHPHQSPSLVRQQTFPHYEASSAT 523
               P+ P+ ++P+  + TP      V           P  SP+L   +  P     ++ 
Sbjct: 501 -GQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSV 559

Query: 524 TSPFF-------KPPAQHLNGSAAFNGVD 545
           + P          PP    + S+  +G D
Sbjct: 560 SGPRLTLALAPGPPPPPSRSPSSTLSGPD 588


>gi|7662236 TSC22 domain family, member 2 [Homo sapiens]
          Length = 780

 Score = 44.3 bits (103), Expect = 3e-04
 Identities = 56/212 (26%), Positives = 76/212 (35%), Gaps = 53/212 (25%)

Query: 322 GEAESISSLCSQITNAFSTPEDPFSSAPMTKPVT--VVAPQSPTFQGTEWGQSSGAASPG 379
           G  ++ SS+ +Q+  A S P +  + AP T P     VAP  PT  G       G   P 
Sbjct: 414 GTGQNASSVGAQLMGASSQPSE--AMAPRTGPAQGGQVAPCQPT--GVPPATVGGVVQPC 469

Query: 380 LFQAGHRRTPSEADRWLEEVSKSVRAQQPQASAAPLQPVLQPPPPTAISQPASPFQGNAF 439
           L  AG                    A QPQ+          PPP    S P S   G   
Sbjct: 470 LGPAG--------------------AGQPQSV---------PPPQMGGSGPLSAVPGG-- 498

Query: 440 LTSQPVPVGVVPALQ--PAFVPAQSYPVANGMPYPAPNVP--------VVGITPSQMVAN 489
                 P  VVP +   PA VPA S P  +      PNVP        +   TP    ++
Sbjct: 499 ------PHAVVPGVPNVPAAVPAPSVPSVSTTSVTMPNVPAPLAQSQQLSSHTPVSRSSS 552

Query: 490 VFGTAGHPQAAHPHQSPSLVRQQTFPHYEASS 521
           +    G P A   H +P+ + Q     ++  +
Sbjct: 553 IIQHVGLPLAPGTHSAPTSLPQSDLSQFQTQT 584


>gi|222418647 mucin 7, secreted precursor [Homo sapiens]
          Length = 377

 Score = 43.9 bits (102), Expect = 4e-04
 Identities = 69/306 (22%), Positives = 104/306 (33%), Gaps = 49/306 (16%)

Query: 239 PSSPTSPTSDATTSLEMNNPHAIPRRHAPIEQLARQGSFRG-------------FPALSQ 285
           P  P SP          NNP   P  H P +   +  S                FP+ S 
Sbjct: 72  PKLPPSP----------NNPPKFPNPHQPPKHPDKNSSVVNPTLVATTQIPSVTFPSAST 121

Query: 286 KMSPFKRQLSLRINELPSTMQRKTDFPIKNAVPEVEGEAESISSLCSQITNAFSTPEDPF 345
           K++       L  N    + +   +     A            +  +  T + +TP  P 
Sbjct: 122 KITTLPNVTFLPQNATTISSRENVNTSSSVATLAPVNSPAPQDTTAAPPTPSATTPAPPS 181

Query: 346 SSAPMTKPVTVVAPQSPTFQGTEWGQSSGA-----ASPGLFQAGHRRTPSEA---DRWLE 397
           SSAP   P T  AP +P+   T+   SS A     A+P    A     PS +   +    
Sbjct: 182 SSAP---PETTAAPPTPSAT-TQAPPSSSAPPETTAAPPTPPATTPAPPSSSAPPETTAA 237

Query: 398 EVSKSVRAQQPQASAAPLQPVLQPPPPTAIS-QPASPFQGNAFLTSQPVPVGVVPALQPA 456
             + S     P +S+AP +    PP P+A +  P+S         + P P    PA    
Sbjct: 238 PPTPSATTPAPLSSSAPPETTAVPPTPSATTLDPSSASAPPETTAAPPTPSATTPA---- 293

Query: 457 FVPAQSYPVANGMPYPAPNVPVVGITPSQMVANVFGTAGHPQAAHPHQSPSLVRQQTFPH 516
                  P ++  P      P+   TP+     +        AA  HQ+ + V  QT   
Sbjct: 294 -------PPSSPAPQETTAAPIT--TPNSSPTTLAPDTSETSAAPTHQTTTSVTTQTTTT 344

Query: 517 YEASSA 522
            + +SA
Sbjct: 345 KQPTSA 350



 Score = 39.7 bits (91), Expect = 0.008
 Identities = 61/305 (20%), Positives = 103/305 (33%), Gaps = 33/305 (10%)

Query: 280 FPALSQKMSPFKRQLSLRINE-----LPSTMQRKTDFPIKNAVPEVEGEAESISSLCSQI 334
           +P L     PF R+    +++     LP +      FP  +  P+   +  S+ +     
Sbjct: 48  YPGLLAHQKPFIRKSYKCLHKRCRPKLPPSPNNPPKFPNPHQPPKHPDKNSSVVNPTLVA 107

Query: 335 TNAFSTPEDPFSSAPMTK-PVTVVAPQSPTFQGTEWGQSSGAASPGLFQAGHRRTPSEAD 393
           T    +   P +S  +T  P     PQ+ T   +    ++ ++   L       +P+  D
Sbjct: 108 TTQIPSVTFPSASTKITTLPNVTFLPQNATTISSRENVNTSSSVATLAPVN---SPAPQD 164

Query: 394 RWLEEVSKSVRAQQPQASAAPLQPVLQPPPPTAISQ-PASPFQGNAFLTSQPVPVGVVPA 452
                 + S     P +S+AP +    PP P+A +Q P S         + P P    PA
Sbjct: 165 TTAAPPTPSATTPAPPSSSAPPETTAAPPTPSATTQAPPSSSAPPETTAAPPTPPATTPA 224

Query: 453 LQPAFVPAQS------------YPVANGMPYPAPNVPVVGITPSQMVANVFGTAGHPQAA 500
              +  P ++             P+++  P   P    V  TPS    +    +  P+  
Sbjct: 225 PPSSSAPPETTAAPPTPSATTPAPLSSSAP---PETTAVPPTPSATTLDPSSASAPPETT 281

Query: 501 HPHQSPSLVRQQTFPHYEASSATTSPFFKPPAQHLNGSAAFNGVDDGRLASADRH---TE 557
               +PS               T +P   P     N S      D    ++A  H   T 
Sbjct: 282 AAPPTPSATTPAPPSSPAPQETTAAPITTP-----NSSPTTLAPDTSETSAAPTHQTTTS 336

Query: 558 VPTGT 562
           V T T
Sbjct: 337 VTTQT 341



 Score = 30.4 bits (67), Expect = 4.9
 Identities = 32/136 (23%), Positives = 48/136 (35%), Gaps = 12/136 (8%)

Query: 232 PGNTAPSPSSPTSPTSDATTSLEMNNPHAIPRRHAPIEQLARQGSFRGFPALSQKMSPFK 291
           P ++AP  ++   PT  ATT        A P   AP E  A   +    PA +   +P  
Sbjct: 180 PSSSAPPETTAAPPTPSATT-------QAPPSSSAPPETTAAPPT---PPATTP--APPS 227

Query: 292 RQLSLRINELPSTMQRKTDFPIKNAVPEVEGEAESISSLCSQITNAFSTPEDPFSSAPMT 351
                     P T    T  P+ ++ P          S  +   ++ S P +  ++ P  
Sbjct: 228 SSAPPETTAAPPTPSATTPAPLSSSAPPETTAVPPTPSATTLDPSSASAPPETTAAPPTP 287

Query: 352 KPVTVVAPQSPTFQGT 367
              T   P SP  Q T
Sbjct: 288 SATTPAPPSSPAPQET 303


>gi|222418649 mucin 7, secreted precursor [Homo sapiens]
          Length = 377

 Score = 43.9 bits (102), Expect = 4e-04
 Identities = 69/306 (22%), Positives = 104/306 (33%), Gaps = 49/306 (16%)

Query: 239 PSSPTSPTSDATTSLEMNNPHAIPRRHAPIEQLARQGSFRG-------------FPALSQ 285
           P  P SP          NNP   P  H P +   +  S                FP+ S 
Sbjct: 72  PKLPPSP----------NNPPKFPNPHQPPKHPDKNSSVVNPTLVATTQIPSVTFPSAST 121

Query: 286 KMSPFKRQLSLRINELPSTMQRKTDFPIKNAVPEVEGEAESISSLCSQITNAFSTPEDPF 345
           K++       L  N    + +   +     A            +  +  T + +TP  P 
Sbjct: 122 KITTLPNVTFLPQNATTISSRENVNTSSSVATLAPVNSPAPQDTTAAPPTPSATTPAPPS 181

Query: 346 SSAPMTKPVTVVAPQSPTFQGTEWGQSSGA-----ASPGLFQAGHRRTPSEA---DRWLE 397
           SSAP   P T  AP +P+   T+   SS A     A+P    A     PS +   +    
Sbjct: 182 SSAP---PETTAAPPTPSAT-TQAPPSSSAPPETTAAPPTPPATTPAPPSSSAPPETTAA 237

Query: 398 EVSKSVRAQQPQASAAPLQPVLQPPPPTAIS-QPASPFQGNAFLTSQPVPVGVVPALQPA 456
             + S     P +S+AP +    PP P+A +  P+S         + P P    PA    
Sbjct: 238 PPTPSATTPAPLSSSAPPETTAVPPTPSATTLDPSSASAPPETTAAPPTPSATTPA---- 293

Query: 457 FVPAQSYPVANGMPYPAPNVPVVGITPSQMVANVFGTAGHPQAAHPHQSPSLVRQQTFPH 516
                  P ++  P      P+   TP+     +        AA  HQ+ + V  QT   
Sbjct: 294 -------PPSSPAPQETTAAPIT--TPNSSPTTLAPDTSETSAAPTHQTTTSVTTQTTTT 344

Query: 517 YEASSA 522
            + +SA
Sbjct: 345 KQPTSA 350



 Score = 39.7 bits (91), Expect = 0.008
 Identities = 61/305 (20%), Positives = 103/305 (33%), Gaps = 33/305 (10%)

Query: 280 FPALSQKMSPFKRQLSLRINE-----LPSTMQRKTDFPIKNAVPEVEGEAESISSLCSQI 334
           +P L     PF R+    +++     LP +      FP  +  P+   +  S+ +     
Sbjct: 48  YPGLLAHQKPFIRKSYKCLHKRCRPKLPPSPNNPPKFPNPHQPPKHPDKNSSVVNPTLVA 107

Query: 335 TNAFSTPEDPFSSAPMTK-PVTVVAPQSPTFQGTEWGQSSGAASPGLFQAGHRRTPSEAD 393
           T    +   P +S  +T  P     PQ+ T   +    ++ ++   L       +P+  D
Sbjct: 108 TTQIPSVTFPSASTKITTLPNVTFLPQNATTISSRENVNTSSSVATLAPVN---SPAPQD 164

Query: 394 RWLEEVSKSVRAQQPQASAAPLQPVLQPPPPTAISQ-PASPFQGNAFLTSQPVPVGVVPA 452
                 + S     P +S+AP +    PP P+A +Q P S         + P P    PA
Sbjct: 165 TTAAPPTPSATTPAPPSSSAPPETTAAPPTPSATTQAPPSSSAPPETTAAPPTPPATTPA 224

Query: 453 LQPAFVPAQS------------YPVANGMPYPAPNVPVVGITPSQMVANVFGTAGHPQAA 500
              +  P ++             P+++  P   P    V  TPS    +    +  P+  
Sbjct: 225 PPSSSAPPETTAAPPTPSATTPAPLSSSAP---PETTAVPPTPSATTLDPSSASAPPETT 281

Query: 501 HPHQSPSLVRQQTFPHYEASSATTSPFFKPPAQHLNGSAAFNGVDDGRLASADRH---TE 557
               +PS               T +P   P     N S      D    ++A  H   T 
Sbjct: 282 AAPPTPSATTPAPPSSPAPQETTAAPITTP-----NSSPTTLAPDTSETSAAPTHQTTTS 336

Query: 558 VPTGT 562
           V T T
Sbjct: 337 VTTQT 341



 Score = 30.4 bits (67), Expect = 4.9
 Identities = 32/136 (23%), Positives = 48/136 (35%), Gaps = 12/136 (8%)

Query: 232 PGNTAPSPSSPTSPTSDATTSLEMNNPHAIPRRHAPIEQLARQGSFRGFPALSQKMSPFK 291
           P ++AP  ++   PT  ATT        A P   AP E  A   +    PA +   +P  
Sbjct: 180 PSSSAPPETTAAPPTPSATT-------QAPPSSSAPPETTAAPPT---PPATTP--APPS 227

Query: 292 RQLSLRINELPSTMQRKTDFPIKNAVPEVEGEAESISSLCSQITNAFSTPEDPFSSAPMT 351
                     P T    T  P+ ++ P          S  +   ++ S P +  ++ P  
Sbjct: 228 SSAPPETTAAPPTPSATTPAPLSSSAPPETTAVPPTPSATTLDPSSASAPPETTAAPPTP 287

Query: 352 KPVTVVAPQSPTFQGT 367
              T   P SP  Q T
Sbjct: 288 SATTPAPPSSPAPQET 303


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.315    0.128    0.385 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 26,059,458
Number of Sequences: 37866
Number of extensions: 1400174
Number of successful extensions: 10180
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 48
Number of HSP's successfully gapped in prelim test: 587
Number of HSP's that attempted gapping in prelim test: 8197
Number of HSP's gapped (non-prelim): 2029
length of query: 603
length of database: 18,247,518
effective HSP length: 108
effective length of query: 495
effective length of database: 14,157,990
effective search space: 7008205050
effective search space used: 7008205050
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.