Guide to the Human Genome
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Search of human proteins with 53759122

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|53759122 adenomatous polyposis coli [Homo sapiens]
         (2843 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|189011568 adenomatous polyposis coli [Homo sapiens]               5614   0.0  
gi|189011566 adenomatous polyposis coli [Homo sapiens]               5614   0.0  
gi|53759122 adenomatous polyposis coli [Homo sapiens]                5614   0.0  
gi|5031587 adenomatosis polyposis coli 2 [Homo sapiens]               873   0.0  
gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens]    95   1e-18
gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens]        94   1e-18
gi|91982772 mucin 17 [Homo sapiens]                                    90   3e-17
gi|42542379 serine/arginine repetitive matrix 1 [Homo sapiens]         73   4e-12
gi|224548936 hypothetical protein LOC100170229 [Homo sapiens]          71   1e-11
gi|161016767 mucin 21 [Homo sapiens]                                   71   2e-11
gi|207113162 Treacher Collins-Franceschetti syndrome 1 isoform e...    70   4e-11
gi|28559039 mediator complex subunit 1 [Homo sapiens]                  69   9e-11
gi|5174573 myeloid/lymphoid or mixed-lineage leukemia trithorax ...    67   2e-10
gi|57164977 Treacher Collins-Franceschetti syndrome 1 isoform a ...    67   3e-10
gi|239743293 PREDICTED: mucin 12 [Homo sapiens]                        66   6e-10
gi|239508976 PREDICTED: mucin 12, cell surface associated [Homo ...    66   6e-10
gi|151301154 mucin 6, gastric [Homo sapiens]                           65   7e-10
gi|50083281 KIAA1853 protein [Homo sapiens]                            65   1e-09
gi|115298682 HBxAg transactivated protein 2 [Homo sapiens]             62   6e-09
gi|89026265 PREDICTED: mucin 12 [Homo sapiens]                         62   8e-09
gi|238624188 diffuse panbronchiolitis critical region 1 protein ...    62   1e-08
gi|239754668 PREDICTED: mucin 12 [Homo sapiens]                        61   2e-08
gi|149944526 additional sex combs like 3 [Homo sapiens]                61   2e-08
gi|207113164 Treacher Collins-Franceschetti syndrome 1 isoform f...    59   5e-08
gi|112821681 G protein-regulated inducer of neurite outgrowth 1 ...    58   2e-07
gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens]     57   3e-07
gi|207113160 Treacher Collins-Franceschetti syndrome 1 isoform d...    56   6e-07
gi|120953251 neuron navigator 3 [Homo sapiens]                         56   6e-07
gi|83367077 mucin 16 [Homo sapiens]                                    55   8e-07
gi|7656879 ALL1 fused gene from 5q31 [Homo sapiens]                    55   8e-07

>gi|189011568 adenomatous polyposis coli [Homo sapiens]
          Length = 2843

 Score = 5614 bits (14564), Expect = 0.0
 Identities = 2843/2843 (100%), Positives = 2843/2843 (100%)

Query: 1    MAAASYDQLLKQVEALKMENSNLRQELEDNSNHLTKLETEASNMKEVLKQLQGSIEDEAM 60
            MAAASYDQLLKQVEALKMENSNLRQELEDNSNHLTKLETEASNMKEVLKQLQGSIEDEAM
Sbjct: 1    MAAASYDQLLKQVEALKMENSNLRQELEDNSNHLTKLETEASNMKEVLKQLQGSIEDEAM 60

Query: 61   ASSGQIDLLERLKELNLDSSNFPGVKLRSKMSLRSYGSREGSVSSRSGECSPVPMGSFPR 120
            ASSGQIDLLERLKELNLDSSNFPGVKLRSKMSLRSYGSREGSVSSRSGECSPVPMGSFPR
Sbjct: 61   ASSGQIDLLERLKELNLDSSNFPGVKLRSKMSLRSYGSREGSVSSRSGECSPVPMGSFPR 120

Query: 121  RGFVNGSRESTGYLEELEKERSLLLADLDKEEKEKDWYYAQLQNLTKRIDSLPLTENFSL 180
            RGFVNGSRESTGYLEELEKERSLLLADLDKEEKEKDWYYAQLQNLTKRIDSLPLTENFSL
Sbjct: 121  RGFVNGSRESTGYLEELEKERSLLLADLDKEEKEKDWYYAQLQNLTKRIDSLPLTENFSL 180

Query: 181  QTDMTRRQLEYEARQIRVAMEEQLGTCQDMEKRAQRRIARIQQIEKDILRIRQLLQSQAT 240
            QTDMTRRQLEYEARQIRVAMEEQLGTCQDMEKRAQRRIARIQQIEKDILRIRQLLQSQAT
Sbjct: 181  QTDMTRRQLEYEARQIRVAMEEQLGTCQDMEKRAQRRIARIQQIEKDILRIRQLLQSQAT 240

Query: 241  EAERSSQNKHETGSHDAERQNEGQGVGEINMATSGNGQGSTTRMDHETASVLSSSSTHSA 300
            EAERSSQNKHETGSHDAERQNEGQGVGEINMATSGNGQGSTTRMDHETASVLSSSSTHSA
Sbjct: 241  EAERSSQNKHETGSHDAERQNEGQGVGEINMATSGNGQGSTTRMDHETASVLSSSSTHSA 300

Query: 301  PRRLTSHLGTKVEMVYSLLSMLGTHDKDDMSRTLLAMSSSQDSCISMRQSGCLPLLIQLL 360
            PRRLTSHLGTKVEMVYSLLSMLGTHDKDDMSRTLLAMSSSQDSCISMRQSGCLPLLIQLL
Sbjct: 301  PRRLTSHLGTKVEMVYSLLSMLGTHDKDDMSRTLLAMSSSQDSCISMRQSGCLPLLIQLL 360

Query: 361  HGNDKDSVLLGNSRGSKEARARASAALHNIIHSQPDDKRGRREIRVLHLLEQIRAYCETC 420
            HGNDKDSVLLGNSRGSKEARARASAALHNIIHSQPDDKRGRREIRVLHLLEQIRAYCETC
Sbjct: 361  HGNDKDSVLLGNSRGSKEARARASAALHNIIHSQPDDKRGRREIRVLHLLEQIRAYCETC 420

Query: 421  WEWQEAHEPGMDQDKNPMPAPVEHQICPAVCVLMKLSFDEEHRHAMNELGGLQAIAELLQ 480
            WEWQEAHEPGMDQDKNPMPAPVEHQICPAVCVLMKLSFDEEHRHAMNELGGLQAIAELLQ
Sbjct: 421  WEWQEAHEPGMDQDKNPMPAPVEHQICPAVCVLMKLSFDEEHRHAMNELGGLQAIAELLQ 480

Query: 481  VDCEMYGLTNDHYSITLRRYAGMALTNLTFGDVANKATLCSMKGCMRALVAQLKSESEDL 540
            VDCEMYGLTNDHYSITLRRYAGMALTNLTFGDVANKATLCSMKGCMRALVAQLKSESEDL
Sbjct: 481  VDCEMYGLTNDHYSITLRRYAGMALTNLTFGDVANKATLCSMKGCMRALVAQLKSESEDL 540

Query: 541  QQVIASVLRNLSWRADVNSKKTLREVGSVKALMECALEVKKESTLKSVLSALWNLSAHCT 600
            QQVIASVLRNLSWRADVNSKKTLREVGSVKALMECALEVKKESTLKSVLSALWNLSAHCT
Sbjct: 541  QQVIASVLRNLSWRADVNSKKTLREVGSVKALMECALEVKKESTLKSVLSALWNLSAHCT 600

Query: 601  ENKADICAVDGALAFLVGTLTYRSQTNTLAIIESGGGILRNVSSLIATNEDHRQILRENN 660
            ENKADICAVDGALAFLVGTLTYRSQTNTLAIIESGGGILRNVSSLIATNEDHRQILRENN
Sbjct: 601  ENKADICAVDGALAFLVGTLTYRSQTNTLAIIESGGGILRNVSSLIATNEDHRQILRENN 660

Query: 661  CLQTLLQHLKSHSLTIVSNACGTLWNLSARNPKDQEALWDMGAVSMLKNLIHSKHKMIAM 720
            CLQTLLQHLKSHSLTIVSNACGTLWNLSARNPKDQEALWDMGAVSMLKNLIHSKHKMIAM
Sbjct: 661  CLQTLLQHLKSHSLTIVSNACGTLWNLSARNPKDQEALWDMGAVSMLKNLIHSKHKMIAM 720

Query: 721  GSAAALRNLMANRPAKYKDANIMSPGSSLPSLHVRKQKALEAELDAQHLSETFDNIDNLS 780
            GSAAALRNLMANRPAKYKDANIMSPGSSLPSLHVRKQKALEAELDAQHLSETFDNIDNLS
Sbjct: 721  GSAAALRNLMANRPAKYKDANIMSPGSSLPSLHVRKQKALEAELDAQHLSETFDNIDNLS 780

Query: 781  PKASHRSKQRHKQSLYGDYVFDTNRHDDNRSDNFNTGNMTVLSPYLNTTVLPSSSSSRGS 840
            PKASHRSKQRHKQSLYGDYVFDTNRHDDNRSDNFNTGNMTVLSPYLNTTVLPSSSSSRGS
Sbjct: 781  PKASHRSKQRHKQSLYGDYVFDTNRHDDNRSDNFNTGNMTVLSPYLNTTVLPSSSSSRGS 840

Query: 841  LDSSRSEKDRSLERERGIGLGNYHPATENPGTSSKRGLQISTTAAQIAKVMEEVSAIHTS 900
            LDSSRSEKDRSLERERGIGLGNYHPATENPGTSSKRGLQISTTAAQIAKVMEEVSAIHTS
Sbjct: 841  LDSSRSEKDRSLERERGIGLGNYHPATENPGTSSKRGLQISTTAAQIAKVMEEVSAIHTS 900

Query: 901  QEDRSSGSTTELHCVTDERNALRRSSAAHTHSNTYNFTKSENSNRTCSMPYAKLEYKRSS 960
            QEDRSSGSTTELHCVTDERNALRRSSAAHTHSNTYNFTKSENSNRTCSMPYAKLEYKRSS
Sbjct: 901  QEDRSSGSTTELHCVTDERNALRRSSAAHTHSNTYNFTKSENSNRTCSMPYAKLEYKRSS 960

Query: 961  NDSLNSVSSSDGYGKRGQMKPSIESYSEDDESKFCSYGQYPADLAHKIHSANHMDDNDGE 1020
            NDSLNSVSSSDGYGKRGQMKPSIESYSEDDESKFCSYGQYPADLAHKIHSANHMDDNDGE
Sbjct: 961  NDSLNSVSSSDGYGKRGQMKPSIESYSEDDESKFCSYGQYPADLAHKIHSANHMDDNDGE 1020

Query: 1021 LDTPINYSLKYSDEQLNSGRQSPSQNERWARPKHIIEDEIKQSEQRQSRNQSTTYPVYTE 1080
            LDTPINYSLKYSDEQLNSGRQSPSQNERWARPKHIIEDEIKQSEQRQSRNQSTTYPVYTE
Sbjct: 1021 LDTPINYSLKYSDEQLNSGRQSPSQNERWARPKHIIEDEIKQSEQRQSRNQSTTYPVYTE 1080

Query: 1081 STDDKHLKFQPHFGQQECVSPYRSRGANGSETNRVGSNHGINQNVSQSLCQEDDYEDDKP 1140
            STDDKHLKFQPHFGQQECVSPYRSRGANGSETNRVGSNHGINQNVSQSLCQEDDYEDDKP
Sbjct: 1081 STDDKHLKFQPHFGQQECVSPYRSRGANGSETNRVGSNHGINQNVSQSLCQEDDYEDDKP 1140

Query: 1141 TNYSERYSEEEQHEEEERPTNYSIKYNEEKRHVDQPIDYSLKYATDIPSSQKQSFSFSKS 1200
            TNYSERYSEEEQHEEEERPTNYSIKYNEEKRHVDQPIDYSLKYATDIPSSQKQSFSFSKS
Sbjct: 1141 TNYSERYSEEEQHEEEERPTNYSIKYNEEKRHVDQPIDYSLKYATDIPSSQKQSFSFSKS 1200

Query: 1201 SSGQSSKTEHMSSSSENTSTPSSNAKRQNQLHPSSAQSRSGQPQKAATCKVSSINQETIQ 1260
            SSGQSSKTEHMSSSSENTSTPSSNAKRQNQLHPSSAQSRSGQPQKAATCKVSSINQETIQ
Sbjct: 1201 SSGQSSKTEHMSSSSENTSTPSSNAKRQNQLHPSSAQSRSGQPQKAATCKVSSINQETIQ 1260

Query: 1261 TYCVEDTPICFSRCSSLSSLSSAEDEIGCNQTTQEADSANTLQIAEIKEKIGTRSAEDPV 1320
            TYCVEDTPICFSRCSSLSSLSSAEDEIGCNQTTQEADSANTLQIAEIKEKIGTRSAEDPV
Sbjct: 1261 TYCVEDTPICFSRCSSLSSLSSAEDEIGCNQTTQEADSANTLQIAEIKEKIGTRSAEDPV 1320

Query: 1321 SEVPAVSQHPRTKSSRLQGSSLSSESARHKAVEFSSGAKSPSKSGAQTPKSPPEHYVQET 1380
            SEVPAVSQHPRTKSSRLQGSSLSSESARHKAVEFSSGAKSPSKSGAQTPKSPPEHYVQET
Sbjct: 1321 SEVPAVSQHPRTKSSRLQGSSLSSESARHKAVEFSSGAKSPSKSGAQTPKSPPEHYVQET 1380

Query: 1381 PLMFSRCTSVSSLDSFESRSIASSVQSEPCSGMVSGIISPSDLPDSPGQTMPPSRSKTPP 1440
            PLMFSRCTSVSSLDSFESRSIASSVQSEPCSGMVSGIISPSDLPDSPGQTMPPSRSKTPP
Sbjct: 1381 PLMFSRCTSVSSLDSFESRSIASSVQSEPCSGMVSGIISPSDLPDSPGQTMPPSRSKTPP 1440

Query: 1441 PPPQTAQTKREVPKNKAPTAEKRESGPKQAAVNAAVQRVQVLPDADTLLHFATESTPDGF 1500
            PPPQTAQTKREVPKNKAPTAEKRESGPKQAAVNAAVQRVQVLPDADTLLHFATESTPDGF
Sbjct: 1441 PPPQTAQTKREVPKNKAPTAEKRESGPKQAAVNAAVQRVQVLPDADTLLHFATESTPDGF 1500

Query: 1501 SCSSSLSALSLDEPFIQKDVELRIMPPVQENDNGNETESEQPKESNENQEKEAEKTIDSE 1560
            SCSSSLSALSLDEPFIQKDVELRIMPPVQENDNGNETESEQPKESNENQEKEAEKTIDSE
Sbjct: 1501 SCSSSLSALSLDEPFIQKDVELRIMPPVQENDNGNETESEQPKESNENQEKEAEKTIDSE 1560

Query: 1561 KDLLDDSDDDDIEILEECIISAMPTKSSRKAKKPAQTASKLPPPVARKPSQLPVYKLLPS 1620
            KDLLDDSDDDDIEILEECIISAMPTKSSRKAKKPAQTASKLPPPVARKPSQLPVYKLLPS
Sbjct: 1561 KDLLDDSDDDDIEILEECIISAMPTKSSRKAKKPAQTASKLPPPVARKPSQLPVYKLLPS 1620

Query: 1621 QNRLQPQKHVSFTPGDDMPRVYCVEGTPINFSTATSLSDLTIESPPNELAAGEGVRGGAQ 1680
            QNRLQPQKHVSFTPGDDMPRVYCVEGTPINFSTATSLSDLTIESPPNELAAGEGVRGGAQ
Sbjct: 1621 QNRLQPQKHVSFTPGDDMPRVYCVEGTPINFSTATSLSDLTIESPPNELAAGEGVRGGAQ 1680

Query: 1681 SGEFEKRDTIPTEGRSTDEAQGGKTSSVTIPELDDNKAEEGDILAECINSAMPKGKSHKP 1740
            SGEFEKRDTIPTEGRSTDEAQGGKTSSVTIPELDDNKAEEGDILAECINSAMPKGKSHKP
Sbjct: 1681 SGEFEKRDTIPTEGRSTDEAQGGKTSSVTIPELDDNKAEEGDILAECINSAMPKGKSHKP 1740

Query: 1741 FRVKKIMDQVQQASASSSAPNKNQLDGKKKKPTSPVKPIPQNTEYRTRVRKNADSKNNLN 1800
            FRVKKIMDQVQQASASSSAPNKNQLDGKKKKPTSPVKPIPQNTEYRTRVRKNADSKNNLN
Sbjct: 1741 FRVKKIMDQVQQASASSSAPNKNQLDGKKKKPTSPVKPIPQNTEYRTRVRKNADSKNNLN 1800

Query: 1801 AERVFSDNKDSKKQNLKNNSKVFNDKLPNNEDRVRGSFAFDSPHHYTPIEGTPYCFSRND 1860
            AERVFSDNKDSKKQNLKNNSKVFNDKLPNNEDRVRGSFAFDSPHHYTPIEGTPYCFSRND
Sbjct: 1801 AERVFSDNKDSKKQNLKNNSKVFNDKLPNNEDRVRGSFAFDSPHHYTPIEGTPYCFSRND 1860

Query: 1861 SLSSLDFDDDDVDLSREKAELRKAKENKESEAKVTSHTELTSNQQSANKTQAIAKQPINR 1920
            SLSSLDFDDDDVDLSREKAELRKAKENKESEAKVTSHTELTSNQQSANKTQAIAKQPINR
Sbjct: 1861 SLSSLDFDDDDVDLSREKAELRKAKENKESEAKVTSHTELTSNQQSANKTQAIAKQPINR 1920

Query: 1921 GQPKPILQKQSTFPQSSKDIPDRGAATDEKLQNFAIENTPVCFSHNSSLSSLSDIDQENN 1980
            GQPKPILQKQSTFPQSSKDIPDRGAATDEKLQNFAIENTPVCFSHNSSLSSLSDIDQENN
Sbjct: 1921 GQPKPILQKQSTFPQSSKDIPDRGAATDEKLQNFAIENTPVCFSHNSSLSSLSDIDQENN 1980

Query: 1981 NKENEPIKETEPPDSQGEPSKPQASGYAPKSFHVEDTPVCFSRNSSLSSLSIDSEDDLLQ 2040
            NKENEPIKETEPPDSQGEPSKPQASGYAPKSFHVEDTPVCFSRNSSLSSLSIDSEDDLLQ
Sbjct: 1981 NKENEPIKETEPPDSQGEPSKPQASGYAPKSFHVEDTPVCFSRNSSLSSLSIDSEDDLLQ 2040

Query: 2041 ECISSAMPKKKKPSRLKGDNEKHSPRNMGGILGEDLTLDLKDIQRPDSEHGLSPDSENFD 2100
            ECISSAMPKKKKPSRLKGDNEKHSPRNMGGILGEDLTLDLKDIQRPDSEHGLSPDSENFD
Sbjct: 2041 ECISSAMPKKKKPSRLKGDNEKHSPRNMGGILGEDLTLDLKDIQRPDSEHGLSPDSENFD 2100

Query: 2101 WKAIQEGANSIVSSLHQAAAAACLSRQASSDSDSILSLKSGISLGSPFHLTPDQEEKPFT 2160
            WKAIQEGANSIVSSLHQAAAAACLSRQASSDSDSILSLKSGISLGSPFHLTPDQEEKPFT
Sbjct: 2101 WKAIQEGANSIVSSLHQAAAAACLSRQASSDSDSILSLKSGISLGSPFHLTPDQEEKPFT 2160

Query: 2161 SNKGPRILKPGEKSTLETKKIESESKGIKGGKKVYKSLITGKVRSNSEISGQMKQPLQAN 2220
            SNKGPRILKPGEKSTLETKKIESESKGIKGGKKVYKSLITGKVRSNSEISGQMKQPLQAN
Sbjct: 2161 SNKGPRILKPGEKSTLETKKIESESKGIKGGKKVYKSLITGKVRSNSEISGQMKQPLQAN 2220

Query: 2221 MPSISRGRTMIHIPGVRNSSSSTSPVSKKGPPLKTPASKSPSEGQTATTSPRGAKPSVKS 2280
            MPSISRGRTMIHIPGVRNSSSSTSPVSKKGPPLKTPASKSPSEGQTATTSPRGAKPSVKS
Sbjct: 2221 MPSISRGRTMIHIPGVRNSSSSTSPVSKKGPPLKTPASKSPSEGQTATTSPRGAKPSVKS 2280

Query: 2281 ELSPVARQTSQIGGSSKAPSRSGSRDSTPSRPAQQPLSRPIQSPGRNSISPGRNGISPPN 2340
            ELSPVARQTSQIGGSSKAPSRSGSRDSTPSRPAQQPLSRPIQSPGRNSISPGRNGISPPN
Sbjct: 2281 ELSPVARQTSQIGGSSKAPSRSGSRDSTPSRPAQQPLSRPIQSPGRNSISPGRNGISPPN 2340

Query: 2341 KLSQLPRTSSPSTASTKSSGSGKMSYTSPGRQMSQQNLTKQTGLSKNASSIPRSESASKG 2400
            KLSQLPRTSSPSTASTKSSGSGKMSYTSPGRQMSQQNLTKQTGLSKNASSIPRSESASKG
Sbjct: 2341 KLSQLPRTSSPSTASTKSSGSGKMSYTSPGRQMSQQNLTKQTGLSKNASSIPRSESASKG 2400

Query: 2401 LNQMNNGNGANKKVELSRMSSTKSSGSESDRSERPVLVRQSTFIKEAPSPTLRRKLEESA 2460
            LNQMNNGNGANKKVELSRMSSTKSSGSESDRSERPVLVRQSTFIKEAPSPTLRRKLEESA
Sbjct: 2401 LNQMNNGNGANKKVELSRMSSTKSSGSESDRSERPVLVRQSTFIKEAPSPTLRRKLEESA 2460

Query: 2461 SFESLSPSSRPASPTRSQAQTPVLSPSLPDMSLSTHSSVQAGGWRKLPPNLSPTIEYNDG 2520
            SFESLSPSSRPASPTRSQAQTPVLSPSLPDMSLSTHSSVQAGGWRKLPPNLSPTIEYNDG
Sbjct: 2461 SFESLSPSSRPASPTRSQAQTPVLSPSLPDMSLSTHSSVQAGGWRKLPPNLSPTIEYNDG 2520

Query: 2521 RPAKRHDIARSHSESPSRLPINRSGTWKREHSKHSSSLPRVSTWRRTGSSSSILSASSES 2580
            RPAKRHDIARSHSESPSRLPINRSGTWKREHSKHSSSLPRVSTWRRTGSSSSILSASSES
Sbjct: 2521 RPAKRHDIARSHSESPSRLPINRSGTWKREHSKHSSSLPRVSTWRRTGSSSSILSASSES 2580

Query: 2581 SEKAKSEDEKHVNSISGTKQSKENQVSAKGTWRKIKENEFSPTNSTSQTVSSGATNGAES 2640
            SEKAKSEDEKHVNSISGTKQSKENQVSAKGTWRKIKENEFSPTNSTSQTVSSGATNGAES
Sbjct: 2581 SEKAKSEDEKHVNSISGTKQSKENQVSAKGTWRKIKENEFSPTNSTSQTVSSGATNGAES 2640

Query: 2641 KTLIYQMAPAVSKTEDVWVRIEDCPINNPRSGRSPTGNTPPVIDSVSEKANPNIKDSKDN 2700
            KTLIYQMAPAVSKTEDVWVRIEDCPINNPRSGRSPTGNTPPVIDSVSEKANPNIKDSKDN
Sbjct: 2641 KTLIYQMAPAVSKTEDVWVRIEDCPINNPRSGRSPTGNTPPVIDSVSEKANPNIKDSKDN 2700

Query: 2701 QAKQNVGNGSVPMRTVGLENRLNSFIQVDAPDQKGTEIKPGQNNPVPVSETNESSIVERT 2760
            QAKQNVGNGSVPMRTVGLENRLNSFIQVDAPDQKGTEIKPGQNNPVPVSETNESSIVERT
Sbjct: 2701 QAKQNVGNGSVPMRTVGLENRLNSFIQVDAPDQKGTEIKPGQNNPVPVSETNESSIVERT 2760

Query: 2761 PFSSSSSSKHSSPSGTVAARVTPFNYNPSPRKSSADSTSARPSQIPTPVNNNTKKRDSKT 2820
            PFSSSSSSKHSSPSGTVAARVTPFNYNPSPRKSSADSTSARPSQIPTPVNNNTKKRDSKT
Sbjct: 2761 PFSSSSSSKHSSPSGTVAARVTPFNYNPSPRKSSADSTSARPSQIPTPVNNNTKKRDSKT 2820

Query: 2821 DSTESSGTQSPKRHSGSYLVTSV 2843
            DSTESSGTQSPKRHSGSYLVTSV
Sbjct: 2821 DSTESSGTQSPKRHSGSYLVTSV 2843


>gi|189011566 adenomatous polyposis coli [Homo sapiens]
          Length = 2843

 Score = 5614 bits (14564), Expect = 0.0
 Identities = 2843/2843 (100%), Positives = 2843/2843 (100%)

Query: 1    MAAASYDQLLKQVEALKMENSNLRQELEDNSNHLTKLETEASNMKEVLKQLQGSIEDEAM 60
            MAAASYDQLLKQVEALKMENSNLRQELEDNSNHLTKLETEASNMKEVLKQLQGSIEDEAM
Sbjct: 1    MAAASYDQLLKQVEALKMENSNLRQELEDNSNHLTKLETEASNMKEVLKQLQGSIEDEAM 60

Query: 61   ASSGQIDLLERLKELNLDSSNFPGVKLRSKMSLRSYGSREGSVSSRSGECSPVPMGSFPR 120
            ASSGQIDLLERLKELNLDSSNFPGVKLRSKMSLRSYGSREGSVSSRSGECSPVPMGSFPR
Sbjct: 61   ASSGQIDLLERLKELNLDSSNFPGVKLRSKMSLRSYGSREGSVSSRSGECSPVPMGSFPR 120

Query: 121  RGFVNGSRESTGYLEELEKERSLLLADLDKEEKEKDWYYAQLQNLTKRIDSLPLTENFSL 180
            RGFVNGSRESTGYLEELEKERSLLLADLDKEEKEKDWYYAQLQNLTKRIDSLPLTENFSL
Sbjct: 121  RGFVNGSRESTGYLEELEKERSLLLADLDKEEKEKDWYYAQLQNLTKRIDSLPLTENFSL 180

Query: 181  QTDMTRRQLEYEARQIRVAMEEQLGTCQDMEKRAQRRIARIQQIEKDILRIRQLLQSQAT 240
            QTDMTRRQLEYEARQIRVAMEEQLGTCQDMEKRAQRRIARIQQIEKDILRIRQLLQSQAT
Sbjct: 181  QTDMTRRQLEYEARQIRVAMEEQLGTCQDMEKRAQRRIARIQQIEKDILRIRQLLQSQAT 240

Query: 241  EAERSSQNKHETGSHDAERQNEGQGVGEINMATSGNGQGSTTRMDHETASVLSSSSTHSA 300
            EAERSSQNKHETGSHDAERQNEGQGVGEINMATSGNGQGSTTRMDHETASVLSSSSTHSA
Sbjct: 241  EAERSSQNKHETGSHDAERQNEGQGVGEINMATSGNGQGSTTRMDHETASVLSSSSTHSA 300

Query: 301  PRRLTSHLGTKVEMVYSLLSMLGTHDKDDMSRTLLAMSSSQDSCISMRQSGCLPLLIQLL 360
            PRRLTSHLGTKVEMVYSLLSMLGTHDKDDMSRTLLAMSSSQDSCISMRQSGCLPLLIQLL
Sbjct: 301  PRRLTSHLGTKVEMVYSLLSMLGTHDKDDMSRTLLAMSSSQDSCISMRQSGCLPLLIQLL 360

Query: 361  HGNDKDSVLLGNSRGSKEARARASAALHNIIHSQPDDKRGRREIRVLHLLEQIRAYCETC 420
            HGNDKDSVLLGNSRGSKEARARASAALHNIIHSQPDDKRGRREIRVLHLLEQIRAYCETC
Sbjct: 361  HGNDKDSVLLGNSRGSKEARARASAALHNIIHSQPDDKRGRREIRVLHLLEQIRAYCETC 420

Query: 421  WEWQEAHEPGMDQDKNPMPAPVEHQICPAVCVLMKLSFDEEHRHAMNELGGLQAIAELLQ 480
            WEWQEAHEPGMDQDKNPMPAPVEHQICPAVCVLMKLSFDEEHRHAMNELGGLQAIAELLQ
Sbjct: 421  WEWQEAHEPGMDQDKNPMPAPVEHQICPAVCVLMKLSFDEEHRHAMNELGGLQAIAELLQ 480

Query: 481  VDCEMYGLTNDHYSITLRRYAGMALTNLTFGDVANKATLCSMKGCMRALVAQLKSESEDL 540
            VDCEMYGLTNDHYSITLRRYAGMALTNLTFGDVANKATLCSMKGCMRALVAQLKSESEDL
Sbjct: 481  VDCEMYGLTNDHYSITLRRYAGMALTNLTFGDVANKATLCSMKGCMRALVAQLKSESEDL 540

Query: 541  QQVIASVLRNLSWRADVNSKKTLREVGSVKALMECALEVKKESTLKSVLSALWNLSAHCT 600
            QQVIASVLRNLSWRADVNSKKTLREVGSVKALMECALEVKKESTLKSVLSALWNLSAHCT
Sbjct: 541  QQVIASVLRNLSWRADVNSKKTLREVGSVKALMECALEVKKESTLKSVLSALWNLSAHCT 600

Query: 601  ENKADICAVDGALAFLVGTLTYRSQTNTLAIIESGGGILRNVSSLIATNEDHRQILRENN 660
            ENKADICAVDGALAFLVGTLTYRSQTNTLAIIESGGGILRNVSSLIATNEDHRQILRENN
Sbjct: 601  ENKADICAVDGALAFLVGTLTYRSQTNTLAIIESGGGILRNVSSLIATNEDHRQILRENN 660

Query: 661  CLQTLLQHLKSHSLTIVSNACGTLWNLSARNPKDQEALWDMGAVSMLKNLIHSKHKMIAM 720
            CLQTLLQHLKSHSLTIVSNACGTLWNLSARNPKDQEALWDMGAVSMLKNLIHSKHKMIAM
Sbjct: 661  CLQTLLQHLKSHSLTIVSNACGTLWNLSARNPKDQEALWDMGAVSMLKNLIHSKHKMIAM 720

Query: 721  GSAAALRNLMANRPAKYKDANIMSPGSSLPSLHVRKQKALEAELDAQHLSETFDNIDNLS 780
            GSAAALRNLMANRPAKYKDANIMSPGSSLPSLHVRKQKALEAELDAQHLSETFDNIDNLS
Sbjct: 721  GSAAALRNLMANRPAKYKDANIMSPGSSLPSLHVRKQKALEAELDAQHLSETFDNIDNLS 780

Query: 781  PKASHRSKQRHKQSLYGDYVFDTNRHDDNRSDNFNTGNMTVLSPYLNTTVLPSSSSSRGS 840
            PKASHRSKQRHKQSLYGDYVFDTNRHDDNRSDNFNTGNMTVLSPYLNTTVLPSSSSSRGS
Sbjct: 781  PKASHRSKQRHKQSLYGDYVFDTNRHDDNRSDNFNTGNMTVLSPYLNTTVLPSSSSSRGS 840

Query: 841  LDSSRSEKDRSLERERGIGLGNYHPATENPGTSSKRGLQISTTAAQIAKVMEEVSAIHTS 900
            LDSSRSEKDRSLERERGIGLGNYHPATENPGTSSKRGLQISTTAAQIAKVMEEVSAIHTS
Sbjct: 841  LDSSRSEKDRSLERERGIGLGNYHPATENPGTSSKRGLQISTTAAQIAKVMEEVSAIHTS 900

Query: 901  QEDRSSGSTTELHCVTDERNALRRSSAAHTHSNTYNFTKSENSNRTCSMPYAKLEYKRSS 960
            QEDRSSGSTTELHCVTDERNALRRSSAAHTHSNTYNFTKSENSNRTCSMPYAKLEYKRSS
Sbjct: 901  QEDRSSGSTTELHCVTDERNALRRSSAAHTHSNTYNFTKSENSNRTCSMPYAKLEYKRSS 960

Query: 961  NDSLNSVSSSDGYGKRGQMKPSIESYSEDDESKFCSYGQYPADLAHKIHSANHMDDNDGE 1020
            NDSLNSVSSSDGYGKRGQMKPSIESYSEDDESKFCSYGQYPADLAHKIHSANHMDDNDGE
Sbjct: 961  NDSLNSVSSSDGYGKRGQMKPSIESYSEDDESKFCSYGQYPADLAHKIHSANHMDDNDGE 1020

Query: 1021 LDTPINYSLKYSDEQLNSGRQSPSQNERWARPKHIIEDEIKQSEQRQSRNQSTTYPVYTE 1080
            LDTPINYSLKYSDEQLNSGRQSPSQNERWARPKHIIEDEIKQSEQRQSRNQSTTYPVYTE
Sbjct: 1021 LDTPINYSLKYSDEQLNSGRQSPSQNERWARPKHIIEDEIKQSEQRQSRNQSTTYPVYTE 1080

Query: 1081 STDDKHLKFQPHFGQQECVSPYRSRGANGSETNRVGSNHGINQNVSQSLCQEDDYEDDKP 1140
            STDDKHLKFQPHFGQQECVSPYRSRGANGSETNRVGSNHGINQNVSQSLCQEDDYEDDKP
Sbjct: 1081 STDDKHLKFQPHFGQQECVSPYRSRGANGSETNRVGSNHGINQNVSQSLCQEDDYEDDKP 1140

Query: 1141 TNYSERYSEEEQHEEEERPTNYSIKYNEEKRHVDQPIDYSLKYATDIPSSQKQSFSFSKS 1200
            TNYSERYSEEEQHEEEERPTNYSIKYNEEKRHVDQPIDYSLKYATDIPSSQKQSFSFSKS
Sbjct: 1141 TNYSERYSEEEQHEEEERPTNYSIKYNEEKRHVDQPIDYSLKYATDIPSSQKQSFSFSKS 1200

Query: 1201 SSGQSSKTEHMSSSSENTSTPSSNAKRQNQLHPSSAQSRSGQPQKAATCKVSSINQETIQ 1260
            SSGQSSKTEHMSSSSENTSTPSSNAKRQNQLHPSSAQSRSGQPQKAATCKVSSINQETIQ
Sbjct: 1201 SSGQSSKTEHMSSSSENTSTPSSNAKRQNQLHPSSAQSRSGQPQKAATCKVSSINQETIQ 1260

Query: 1261 TYCVEDTPICFSRCSSLSSLSSAEDEIGCNQTTQEADSANTLQIAEIKEKIGTRSAEDPV 1320
            TYCVEDTPICFSRCSSLSSLSSAEDEIGCNQTTQEADSANTLQIAEIKEKIGTRSAEDPV
Sbjct: 1261 TYCVEDTPICFSRCSSLSSLSSAEDEIGCNQTTQEADSANTLQIAEIKEKIGTRSAEDPV 1320

Query: 1321 SEVPAVSQHPRTKSSRLQGSSLSSESARHKAVEFSSGAKSPSKSGAQTPKSPPEHYVQET 1380
            SEVPAVSQHPRTKSSRLQGSSLSSESARHKAVEFSSGAKSPSKSGAQTPKSPPEHYVQET
Sbjct: 1321 SEVPAVSQHPRTKSSRLQGSSLSSESARHKAVEFSSGAKSPSKSGAQTPKSPPEHYVQET 1380

Query: 1381 PLMFSRCTSVSSLDSFESRSIASSVQSEPCSGMVSGIISPSDLPDSPGQTMPPSRSKTPP 1440
            PLMFSRCTSVSSLDSFESRSIASSVQSEPCSGMVSGIISPSDLPDSPGQTMPPSRSKTPP
Sbjct: 1381 PLMFSRCTSVSSLDSFESRSIASSVQSEPCSGMVSGIISPSDLPDSPGQTMPPSRSKTPP 1440

Query: 1441 PPPQTAQTKREVPKNKAPTAEKRESGPKQAAVNAAVQRVQVLPDADTLLHFATESTPDGF 1500
            PPPQTAQTKREVPKNKAPTAEKRESGPKQAAVNAAVQRVQVLPDADTLLHFATESTPDGF
Sbjct: 1441 PPPQTAQTKREVPKNKAPTAEKRESGPKQAAVNAAVQRVQVLPDADTLLHFATESTPDGF 1500

Query: 1501 SCSSSLSALSLDEPFIQKDVELRIMPPVQENDNGNETESEQPKESNENQEKEAEKTIDSE 1560
            SCSSSLSALSLDEPFIQKDVELRIMPPVQENDNGNETESEQPKESNENQEKEAEKTIDSE
Sbjct: 1501 SCSSSLSALSLDEPFIQKDVELRIMPPVQENDNGNETESEQPKESNENQEKEAEKTIDSE 1560

Query: 1561 KDLLDDSDDDDIEILEECIISAMPTKSSRKAKKPAQTASKLPPPVARKPSQLPVYKLLPS 1620
            KDLLDDSDDDDIEILEECIISAMPTKSSRKAKKPAQTASKLPPPVARKPSQLPVYKLLPS
Sbjct: 1561 KDLLDDSDDDDIEILEECIISAMPTKSSRKAKKPAQTASKLPPPVARKPSQLPVYKLLPS 1620

Query: 1621 QNRLQPQKHVSFTPGDDMPRVYCVEGTPINFSTATSLSDLTIESPPNELAAGEGVRGGAQ 1680
            QNRLQPQKHVSFTPGDDMPRVYCVEGTPINFSTATSLSDLTIESPPNELAAGEGVRGGAQ
Sbjct: 1621 QNRLQPQKHVSFTPGDDMPRVYCVEGTPINFSTATSLSDLTIESPPNELAAGEGVRGGAQ 1680

Query: 1681 SGEFEKRDTIPTEGRSTDEAQGGKTSSVTIPELDDNKAEEGDILAECINSAMPKGKSHKP 1740
            SGEFEKRDTIPTEGRSTDEAQGGKTSSVTIPELDDNKAEEGDILAECINSAMPKGKSHKP
Sbjct: 1681 SGEFEKRDTIPTEGRSTDEAQGGKTSSVTIPELDDNKAEEGDILAECINSAMPKGKSHKP 1740

Query: 1741 FRVKKIMDQVQQASASSSAPNKNQLDGKKKKPTSPVKPIPQNTEYRTRVRKNADSKNNLN 1800
            FRVKKIMDQVQQASASSSAPNKNQLDGKKKKPTSPVKPIPQNTEYRTRVRKNADSKNNLN
Sbjct: 1741 FRVKKIMDQVQQASASSSAPNKNQLDGKKKKPTSPVKPIPQNTEYRTRVRKNADSKNNLN 1800

Query: 1801 AERVFSDNKDSKKQNLKNNSKVFNDKLPNNEDRVRGSFAFDSPHHYTPIEGTPYCFSRND 1860
            AERVFSDNKDSKKQNLKNNSKVFNDKLPNNEDRVRGSFAFDSPHHYTPIEGTPYCFSRND
Sbjct: 1801 AERVFSDNKDSKKQNLKNNSKVFNDKLPNNEDRVRGSFAFDSPHHYTPIEGTPYCFSRND 1860

Query: 1861 SLSSLDFDDDDVDLSREKAELRKAKENKESEAKVTSHTELTSNQQSANKTQAIAKQPINR 1920
            SLSSLDFDDDDVDLSREKAELRKAKENKESEAKVTSHTELTSNQQSANKTQAIAKQPINR
Sbjct: 1861 SLSSLDFDDDDVDLSREKAELRKAKENKESEAKVTSHTELTSNQQSANKTQAIAKQPINR 1920

Query: 1921 GQPKPILQKQSTFPQSSKDIPDRGAATDEKLQNFAIENTPVCFSHNSSLSSLSDIDQENN 1980
            GQPKPILQKQSTFPQSSKDIPDRGAATDEKLQNFAIENTPVCFSHNSSLSSLSDIDQENN
Sbjct: 1921 GQPKPILQKQSTFPQSSKDIPDRGAATDEKLQNFAIENTPVCFSHNSSLSSLSDIDQENN 1980

Query: 1981 NKENEPIKETEPPDSQGEPSKPQASGYAPKSFHVEDTPVCFSRNSSLSSLSIDSEDDLLQ 2040
            NKENEPIKETEPPDSQGEPSKPQASGYAPKSFHVEDTPVCFSRNSSLSSLSIDSEDDLLQ
Sbjct: 1981 NKENEPIKETEPPDSQGEPSKPQASGYAPKSFHVEDTPVCFSRNSSLSSLSIDSEDDLLQ 2040

Query: 2041 ECISSAMPKKKKPSRLKGDNEKHSPRNMGGILGEDLTLDLKDIQRPDSEHGLSPDSENFD 2100
            ECISSAMPKKKKPSRLKGDNEKHSPRNMGGILGEDLTLDLKDIQRPDSEHGLSPDSENFD
Sbjct: 2041 ECISSAMPKKKKPSRLKGDNEKHSPRNMGGILGEDLTLDLKDIQRPDSEHGLSPDSENFD 2100

Query: 2101 WKAIQEGANSIVSSLHQAAAAACLSRQASSDSDSILSLKSGISLGSPFHLTPDQEEKPFT 2160
            WKAIQEGANSIVSSLHQAAAAACLSRQASSDSDSILSLKSGISLGSPFHLTPDQEEKPFT
Sbjct: 2101 WKAIQEGANSIVSSLHQAAAAACLSRQASSDSDSILSLKSGISLGSPFHLTPDQEEKPFT 2160

Query: 2161 SNKGPRILKPGEKSTLETKKIESESKGIKGGKKVYKSLITGKVRSNSEISGQMKQPLQAN 2220
            SNKGPRILKPGEKSTLETKKIESESKGIKGGKKVYKSLITGKVRSNSEISGQMKQPLQAN
Sbjct: 2161 SNKGPRILKPGEKSTLETKKIESESKGIKGGKKVYKSLITGKVRSNSEISGQMKQPLQAN 2220

Query: 2221 MPSISRGRTMIHIPGVRNSSSSTSPVSKKGPPLKTPASKSPSEGQTATTSPRGAKPSVKS 2280
            MPSISRGRTMIHIPGVRNSSSSTSPVSKKGPPLKTPASKSPSEGQTATTSPRGAKPSVKS
Sbjct: 2221 MPSISRGRTMIHIPGVRNSSSSTSPVSKKGPPLKTPASKSPSEGQTATTSPRGAKPSVKS 2280

Query: 2281 ELSPVARQTSQIGGSSKAPSRSGSRDSTPSRPAQQPLSRPIQSPGRNSISPGRNGISPPN 2340
            ELSPVARQTSQIGGSSKAPSRSGSRDSTPSRPAQQPLSRPIQSPGRNSISPGRNGISPPN
Sbjct: 2281 ELSPVARQTSQIGGSSKAPSRSGSRDSTPSRPAQQPLSRPIQSPGRNSISPGRNGISPPN 2340

Query: 2341 KLSQLPRTSSPSTASTKSSGSGKMSYTSPGRQMSQQNLTKQTGLSKNASSIPRSESASKG 2400
            KLSQLPRTSSPSTASTKSSGSGKMSYTSPGRQMSQQNLTKQTGLSKNASSIPRSESASKG
Sbjct: 2341 KLSQLPRTSSPSTASTKSSGSGKMSYTSPGRQMSQQNLTKQTGLSKNASSIPRSESASKG 2400

Query: 2401 LNQMNNGNGANKKVELSRMSSTKSSGSESDRSERPVLVRQSTFIKEAPSPTLRRKLEESA 2460
            LNQMNNGNGANKKVELSRMSSTKSSGSESDRSERPVLVRQSTFIKEAPSPTLRRKLEESA
Sbjct: 2401 LNQMNNGNGANKKVELSRMSSTKSSGSESDRSERPVLVRQSTFIKEAPSPTLRRKLEESA 2460

Query: 2461 SFESLSPSSRPASPTRSQAQTPVLSPSLPDMSLSTHSSVQAGGWRKLPPNLSPTIEYNDG 2520
            SFESLSPSSRPASPTRSQAQTPVLSPSLPDMSLSTHSSVQAGGWRKLPPNLSPTIEYNDG
Sbjct: 2461 SFESLSPSSRPASPTRSQAQTPVLSPSLPDMSLSTHSSVQAGGWRKLPPNLSPTIEYNDG 2520

Query: 2521 RPAKRHDIARSHSESPSRLPINRSGTWKREHSKHSSSLPRVSTWRRTGSSSSILSASSES 2580
            RPAKRHDIARSHSESPSRLPINRSGTWKREHSKHSSSLPRVSTWRRTGSSSSILSASSES
Sbjct: 2521 RPAKRHDIARSHSESPSRLPINRSGTWKREHSKHSSSLPRVSTWRRTGSSSSILSASSES 2580

Query: 2581 SEKAKSEDEKHVNSISGTKQSKENQVSAKGTWRKIKENEFSPTNSTSQTVSSGATNGAES 2640
            SEKAKSEDEKHVNSISGTKQSKENQVSAKGTWRKIKENEFSPTNSTSQTVSSGATNGAES
Sbjct: 2581 SEKAKSEDEKHVNSISGTKQSKENQVSAKGTWRKIKENEFSPTNSTSQTVSSGATNGAES 2640

Query: 2641 KTLIYQMAPAVSKTEDVWVRIEDCPINNPRSGRSPTGNTPPVIDSVSEKANPNIKDSKDN 2700
            KTLIYQMAPAVSKTEDVWVRIEDCPINNPRSGRSPTGNTPPVIDSVSEKANPNIKDSKDN
Sbjct: 2641 KTLIYQMAPAVSKTEDVWVRIEDCPINNPRSGRSPTGNTPPVIDSVSEKANPNIKDSKDN 2700

Query: 2701 QAKQNVGNGSVPMRTVGLENRLNSFIQVDAPDQKGTEIKPGQNNPVPVSETNESSIVERT 2760
            QAKQNVGNGSVPMRTVGLENRLNSFIQVDAPDQKGTEIKPGQNNPVPVSETNESSIVERT
Sbjct: 2701 QAKQNVGNGSVPMRTVGLENRLNSFIQVDAPDQKGTEIKPGQNNPVPVSETNESSIVERT 2760

Query: 2761 PFSSSSSSKHSSPSGTVAARVTPFNYNPSPRKSSADSTSARPSQIPTPVNNNTKKRDSKT 2820
            PFSSSSSSKHSSPSGTVAARVTPFNYNPSPRKSSADSTSARPSQIPTPVNNNTKKRDSKT
Sbjct: 2761 PFSSSSSSKHSSPSGTVAARVTPFNYNPSPRKSSADSTSARPSQIPTPVNNNTKKRDSKT 2820

Query: 2821 DSTESSGTQSPKRHSGSYLVTSV 2843
            DSTESSGTQSPKRHSGSYLVTSV
Sbjct: 2821 DSTESSGTQSPKRHSGSYLVTSV 2843


>gi|53759122 adenomatous polyposis coli [Homo sapiens]
          Length = 2843

 Score = 5614 bits (14564), Expect = 0.0
 Identities = 2843/2843 (100%), Positives = 2843/2843 (100%)

Query: 1    MAAASYDQLLKQVEALKMENSNLRQELEDNSNHLTKLETEASNMKEVLKQLQGSIEDEAM 60
            MAAASYDQLLKQVEALKMENSNLRQELEDNSNHLTKLETEASNMKEVLKQLQGSIEDEAM
Sbjct: 1    MAAASYDQLLKQVEALKMENSNLRQELEDNSNHLTKLETEASNMKEVLKQLQGSIEDEAM 60

Query: 61   ASSGQIDLLERLKELNLDSSNFPGVKLRSKMSLRSYGSREGSVSSRSGECSPVPMGSFPR 120
            ASSGQIDLLERLKELNLDSSNFPGVKLRSKMSLRSYGSREGSVSSRSGECSPVPMGSFPR
Sbjct: 61   ASSGQIDLLERLKELNLDSSNFPGVKLRSKMSLRSYGSREGSVSSRSGECSPVPMGSFPR 120

Query: 121  RGFVNGSRESTGYLEELEKERSLLLADLDKEEKEKDWYYAQLQNLTKRIDSLPLTENFSL 180
            RGFVNGSRESTGYLEELEKERSLLLADLDKEEKEKDWYYAQLQNLTKRIDSLPLTENFSL
Sbjct: 121  RGFVNGSRESTGYLEELEKERSLLLADLDKEEKEKDWYYAQLQNLTKRIDSLPLTENFSL 180

Query: 181  QTDMTRRQLEYEARQIRVAMEEQLGTCQDMEKRAQRRIARIQQIEKDILRIRQLLQSQAT 240
            QTDMTRRQLEYEARQIRVAMEEQLGTCQDMEKRAQRRIARIQQIEKDILRIRQLLQSQAT
Sbjct: 181  QTDMTRRQLEYEARQIRVAMEEQLGTCQDMEKRAQRRIARIQQIEKDILRIRQLLQSQAT 240

Query: 241  EAERSSQNKHETGSHDAERQNEGQGVGEINMATSGNGQGSTTRMDHETASVLSSSSTHSA 300
            EAERSSQNKHETGSHDAERQNEGQGVGEINMATSGNGQGSTTRMDHETASVLSSSSTHSA
Sbjct: 241  EAERSSQNKHETGSHDAERQNEGQGVGEINMATSGNGQGSTTRMDHETASVLSSSSTHSA 300

Query: 301  PRRLTSHLGTKVEMVYSLLSMLGTHDKDDMSRTLLAMSSSQDSCISMRQSGCLPLLIQLL 360
            PRRLTSHLGTKVEMVYSLLSMLGTHDKDDMSRTLLAMSSSQDSCISMRQSGCLPLLIQLL
Sbjct: 301  PRRLTSHLGTKVEMVYSLLSMLGTHDKDDMSRTLLAMSSSQDSCISMRQSGCLPLLIQLL 360

Query: 361  HGNDKDSVLLGNSRGSKEARARASAALHNIIHSQPDDKRGRREIRVLHLLEQIRAYCETC 420
            HGNDKDSVLLGNSRGSKEARARASAALHNIIHSQPDDKRGRREIRVLHLLEQIRAYCETC
Sbjct: 361  HGNDKDSVLLGNSRGSKEARARASAALHNIIHSQPDDKRGRREIRVLHLLEQIRAYCETC 420

Query: 421  WEWQEAHEPGMDQDKNPMPAPVEHQICPAVCVLMKLSFDEEHRHAMNELGGLQAIAELLQ 480
            WEWQEAHEPGMDQDKNPMPAPVEHQICPAVCVLMKLSFDEEHRHAMNELGGLQAIAELLQ
Sbjct: 421  WEWQEAHEPGMDQDKNPMPAPVEHQICPAVCVLMKLSFDEEHRHAMNELGGLQAIAELLQ 480

Query: 481  VDCEMYGLTNDHYSITLRRYAGMALTNLTFGDVANKATLCSMKGCMRALVAQLKSESEDL 540
            VDCEMYGLTNDHYSITLRRYAGMALTNLTFGDVANKATLCSMKGCMRALVAQLKSESEDL
Sbjct: 481  VDCEMYGLTNDHYSITLRRYAGMALTNLTFGDVANKATLCSMKGCMRALVAQLKSESEDL 540

Query: 541  QQVIASVLRNLSWRADVNSKKTLREVGSVKALMECALEVKKESTLKSVLSALWNLSAHCT 600
            QQVIASVLRNLSWRADVNSKKTLREVGSVKALMECALEVKKESTLKSVLSALWNLSAHCT
Sbjct: 541  QQVIASVLRNLSWRADVNSKKTLREVGSVKALMECALEVKKESTLKSVLSALWNLSAHCT 600

Query: 601  ENKADICAVDGALAFLVGTLTYRSQTNTLAIIESGGGILRNVSSLIATNEDHRQILRENN 660
            ENKADICAVDGALAFLVGTLTYRSQTNTLAIIESGGGILRNVSSLIATNEDHRQILRENN
Sbjct: 601  ENKADICAVDGALAFLVGTLTYRSQTNTLAIIESGGGILRNVSSLIATNEDHRQILRENN 660

Query: 661  CLQTLLQHLKSHSLTIVSNACGTLWNLSARNPKDQEALWDMGAVSMLKNLIHSKHKMIAM 720
            CLQTLLQHLKSHSLTIVSNACGTLWNLSARNPKDQEALWDMGAVSMLKNLIHSKHKMIAM
Sbjct: 661  CLQTLLQHLKSHSLTIVSNACGTLWNLSARNPKDQEALWDMGAVSMLKNLIHSKHKMIAM 720

Query: 721  GSAAALRNLMANRPAKYKDANIMSPGSSLPSLHVRKQKALEAELDAQHLSETFDNIDNLS 780
            GSAAALRNLMANRPAKYKDANIMSPGSSLPSLHVRKQKALEAELDAQHLSETFDNIDNLS
Sbjct: 721  GSAAALRNLMANRPAKYKDANIMSPGSSLPSLHVRKQKALEAELDAQHLSETFDNIDNLS 780

Query: 781  PKASHRSKQRHKQSLYGDYVFDTNRHDDNRSDNFNTGNMTVLSPYLNTTVLPSSSSSRGS 840
            PKASHRSKQRHKQSLYGDYVFDTNRHDDNRSDNFNTGNMTVLSPYLNTTVLPSSSSSRGS
Sbjct: 781  PKASHRSKQRHKQSLYGDYVFDTNRHDDNRSDNFNTGNMTVLSPYLNTTVLPSSSSSRGS 840

Query: 841  LDSSRSEKDRSLERERGIGLGNYHPATENPGTSSKRGLQISTTAAQIAKVMEEVSAIHTS 900
            LDSSRSEKDRSLERERGIGLGNYHPATENPGTSSKRGLQISTTAAQIAKVMEEVSAIHTS
Sbjct: 841  LDSSRSEKDRSLERERGIGLGNYHPATENPGTSSKRGLQISTTAAQIAKVMEEVSAIHTS 900

Query: 901  QEDRSSGSTTELHCVTDERNALRRSSAAHTHSNTYNFTKSENSNRTCSMPYAKLEYKRSS 960
            QEDRSSGSTTELHCVTDERNALRRSSAAHTHSNTYNFTKSENSNRTCSMPYAKLEYKRSS
Sbjct: 901  QEDRSSGSTTELHCVTDERNALRRSSAAHTHSNTYNFTKSENSNRTCSMPYAKLEYKRSS 960

Query: 961  NDSLNSVSSSDGYGKRGQMKPSIESYSEDDESKFCSYGQYPADLAHKIHSANHMDDNDGE 1020
            NDSLNSVSSSDGYGKRGQMKPSIESYSEDDESKFCSYGQYPADLAHKIHSANHMDDNDGE
Sbjct: 961  NDSLNSVSSSDGYGKRGQMKPSIESYSEDDESKFCSYGQYPADLAHKIHSANHMDDNDGE 1020

Query: 1021 LDTPINYSLKYSDEQLNSGRQSPSQNERWARPKHIIEDEIKQSEQRQSRNQSTTYPVYTE 1080
            LDTPINYSLKYSDEQLNSGRQSPSQNERWARPKHIIEDEIKQSEQRQSRNQSTTYPVYTE
Sbjct: 1021 LDTPINYSLKYSDEQLNSGRQSPSQNERWARPKHIIEDEIKQSEQRQSRNQSTTYPVYTE 1080

Query: 1081 STDDKHLKFQPHFGQQECVSPYRSRGANGSETNRVGSNHGINQNVSQSLCQEDDYEDDKP 1140
            STDDKHLKFQPHFGQQECVSPYRSRGANGSETNRVGSNHGINQNVSQSLCQEDDYEDDKP
Sbjct: 1081 STDDKHLKFQPHFGQQECVSPYRSRGANGSETNRVGSNHGINQNVSQSLCQEDDYEDDKP 1140

Query: 1141 TNYSERYSEEEQHEEEERPTNYSIKYNEEKRHVDQPIDYSLKYATDIPSSQKQSFSFSKS 1200
            TNYSERYSEEEQHEEEERPTNYSIKYNEEKRHVDQPIDYSLKYATDIPSSQKQSFSFSKS
Sbjct: 1141 TNYSERYSEEEQHEEEERPTNYSIKYNEEKRHVDQPIDYSLKYATDIPSSQKQSFSFSKS 1200

Query: 1201 SSGQSSKTEHMSSSSENTSTPSSNAKRQNQLHPSSAQSRSGQPQKAATCKVSSINQETIQ 1260
            SSGQSSKTEHMSSSSENTSTPSSNAKRQNQLHPSSAQSRSGQPQKAATCKVSSINQETIQ
Sbjct: 1201 SSGQSSKTEHMSSSSENTSTPSSNAKRQNQLHPSSAQSRSGQPQKAATCKVSSINQETIQ 1260

Query: 1261 TYCVEDTPICFSRCSSLSSLSSAEDEIGCNQTTQEADSANTLQIAEIKEKIGTRSAEDPV 1320
            TYCVEDTPICFSRCSSLSSLSSAEDEIGCNQTTQEADSANTLQIAEIKEKIGTRSAEDPV
Sbjct: 1261 TYCVEDTPICFSRCSSLSSLSSAEDEIGCNQTTQEADSANTLQIAEIKEKIGTRSAEDPV 1320

Query: 1321 SEVPAVSQHPRTKSSRLQGSSLSSESARHKAVEFSSGAKSPSKSGAQTPKSPPEHYVQET 1380
            SEVPAVSQHPRTKSSRLQGSSLSSESARHKAVEFSSGAKSPSKSGAQTPKSPPEHYVQET
Sbjct: 1321 SEVPAVSQHPRTKSSRLQGSSLSSESARHKAVEFSSGAKSPSKSGAQTPKSPPEHYVQET 1380

Query: 1381 PLMFSRCTSVSSLDSFESRSIASSVQSEPCSGMVSGIISPSDLPDSPGQTMPPSRSKTPP 1440
            PLMFSRCTSVSSLDSFESRSIASSVQSEPCSGMVSGIISPSDLPDSPGQTMPPSRSKTPP
Sbjct: 1381 PLMFSRCTSVSSLDSFESRSIASSVQSEPCSGMVSGIISPSDLPDSPGQTMPPSRSKTPP 1440

Query: 1441 PPPQTAQTKREVPKNKAPTAEKRESGPKQAAVNAAVQRVQVLPDADTLLHFATESTPDGF 1500
            PPPQTAQTKREVPKNKAPTAEKRESGPKQAAVNAAVQRVQVLPDADTLLHFATESTPDGF
Sbjct: 1441 PPPQTAQTKREVPKNKAPTAEKRESGPKQAAVNAAVQRVQVLPDADTLLHFATESTPDGF 1500

Query: 1501 SCSSSLSALSLDEPFIQKDVELRIMPPVQENDNGNETESEQPKESNENQEKEAEKTIDSE 1560
            SCSSSLSALSLDEPFIQKDVELRIMPPVQENDNGNETESEQPKESNENQEKEAEKTIDSE
Sbjct: 1501 SCSSSLSALSLDEPFIQKDVELRIMPPVQENDNGNETESEQPKESNENQEKEAEKTIDSE 1560

Query: 1561 KDLLDDSDDDDIEILEECIISAMPTKSSRKAKKPAQTASKLPPPVARKPSQLPVYKLLPS 1620
            KDLLDDSDDDDIEILEECIISAMPTKSSRKAKKPAQTASKLPPPVARKPSQLPVYKLLPS
Sbjct: 1561 KDLLDDSDDDDIEILEECIISAMPTKSSRKAKKPAQTASKLPPPVARKPSQLPVYKLLPS 1620

Query: 1621 QNRLQPQKHVSFTPGDDMPRVYCVEGTPINFSTATSLSDLTIESPPNELAAGEGVRGGAQ 1680
            QNRLQPQKHVSFTPGDDMPRVYCVEGTPINFSTATSLSDLTIESPPNELAAGEGVRGGAQ
Sbjct: 1621 QNRLQPQKHVSFTPGDDMPRVYCVEGTPINFSTATSLSDLTIESPPNELAAGEGVRGGAQ 1680

Query: 1681 SGEFEKRDTIPTEGRSTDEAQGGKTSSVTIPELDDNKAEEGDILAECINSAMPKGKSHKP 1740
            SGEFEKRDTIPTEGRSTDEAQGGKTSSVTIPELDDNKAEEGDILAECINSAMPKGKSHKP
Sbjct: 1681 SGEFEKRDTIPTEGRSTDEAQGGKTSSVTIPELDDNKAEEGDILAECINSAMPKGKSHKP 1740

Query: 1741 FRVKKIMDQVQQASASSSAPNKNQLDGKKKKPTSPVKPIPQNTEYRTRVRKNADSKNNLN 1800
            FRVKKIMDQVQQASASSSAPNKNQLDGKKKKPTSPVKPIPQNTEYRTRVRKNADSKNNLN
Sbjct: 1741 FRVKKIMDQVQQASASSSAPNKNQLDGKKKKPTSPVKPIPQNTEYRTRVRKNADSKNNLN 1800

Query: 1801 AERVFSDNKDSKKQNLKNNSKVFNDKLPNNEDRVRGSFAFDSPHHYTPIEGTPYCFSRND 1860
            AERVFSDNKDSKKQNLKNNSKVFNDKLPNNEDRVRGSFAFDSPHHYTPIEGTPYCFSRND
Sbjct: 1801 AERVFSDNKDSKKQNLKNNSKVFNDKLPNNEDRVRGSFAFDSPHHYTPIEGTPYCFSRND 1860

Query: 1861 SLSSLDFDDDDVDLSREKAELRKAKENKESEAKVTSHTELTSNQQSANKTQAIAKQPINR 1920
            SLSSLDFDDDDVDLSREKAELRKAKENKESEAKVTSHTELTSNQQSANKTQAIAKQPINR
Sbjct: 1861 SLSSLDFDDDDVDLSREKAELRKAKENKESEAKVTSHTELTSNQQSANKTQAIAKQPINR 1920

Query: 1921 GQPKPILQKQSTFPQSSKDIPDRGAATDEKLQNFAIENTPVCFSHNSSLSSLSDIDQENN 1980
            GQPKPILQKQSTFPQSSKDIPDRGAATDEKLQNFAIENTPVCFSHNSSLSSLSDIDQENN
Sbjct: 1921 GQPKPILQKQSTFPQSSKDIPDRGAATDEKLQNFAIENTPVCFSHNSSLSSLSDIDQENN 1980

Query: 1981 NKENEPIKETEPPDSQGEPSKPQASGYAPKSFHVEDTPVCFSRNSSLSSLSIDSEDDLLQ 2040
            NKENEPIKETEPPDSQGEPSKPQASGYAPKSFHVEDTPVCFSRNSSLSSLSIDSEDDLLQ
Sbjct: 1981 NKENEPIKETEPPDSQGEPSKPQASGYAPKSFHVEDTPVCFSRNSSLSSLSIDSEDDLLQ 2040

Query: 2041 ECISSAMPKKKKPSRLKGDNEKHSPRNMGGILGEDLTLDLKDIQRPDSEHGLSPDSENFD 2100
            ECISSAMPKKKKPSRLKGDNEKHSPRNMGGILGEDLTLDLKDIQRPDSEHGLSPDSENFD
Sbjct: 2041 ECISSAMPKKKKPSRLKGDNEKHSPRNMGGILGEDLTLDLKDIQRPDSEHGLSPDSENFD 2100

Query: 2101 WKAIQEGANSIVSSLHQAAAAACLSRQASSDSDSILSLKSGISLGSPFHLTPDQEEKPFT 2160
            WKAIQEGANSIVSSLHQAAAAACLSRQASSDSDSILSLKSGISLGSPFHLTPDQEEKPFT
Sbjct: 2101 WKAIQEGANSIVSSLHQAAAAACLSRQASSDSDSILSLKSGISLGSPFHLTPDQEEKPFT 2160

Query: 2161 SNKGPRILKPGEKSTLETKKIESESKGIKGGKKVYKSLITGKVRSNSEISGQMKQPLQAN 2220
            SNKGPRILKPGEKSTLETKKIESESKGIKGGKKVYKSLITGKVRSNSEISGQMKQPLQAN
Sbjct: 2161 SNKGPRILKPGEKSTLETKKIESESKGIKGGKKVYKSLITGKVRSNSEISGQMKQPLQAN 2220

Query: 2221 MPSISRGRTMIHIPGVRNSSSSTSPVSKKGPPLKTPASKSPSEGQTATTSPRGAKPSVKS 2280
            MPSISRGRTMIHIPGVRNSSSSTSPVSKKGPPLKTPASKSPSEGQTATTSPRGAKPSVKS
Sbjct: 2221 MPSISRGRTMIHIPGVRNSSSSTSPVSKKGPPLKTPASKSPSEGQTATTSPRGAKPSVKS 2280

Query: 2281 ELSPVARQTSQIGGSSKAPSRSGSRDSTPSRPAQQPLSRPIQSPGRNSISPGRNGISPPN 2340
            ELSPVARQTSQIGGSSKAPSRSGSRDSTPSRPAQQPLSRPIQSPGRNSISPGRNGISPPN
Sbjct: 2281 ELSPVARQTSQIGGSSKAPSRSGSRDSTPSRPAQQPLSRPIQSPGRNSISPGRNGISPPN 2340

Query: 2341 KLSQLPRTSSPSTASTKSSGSGKMSYTSPGRQMSQQNLTKQTGLSKNASSIPRSESASKG 2400
            KLSQLPRTSSPSTASTKSSGSGKMSYTSPGRQMSQQNLTKQTGLSKNASSIPRSESASKG
Sbjct: 2341 KLSQLPRTSSPSTASTKSSGSGKMSYTSPGRQMSQQNLTKQTGLSKNASSIPRSESASKG 2400

Query: 2401 LNQMNNGNGANKKVELSRMSSTKSSGSESDRSERPVLVRQSTFIKEAPSPTLRRKLEESA 2460
            LNQMNNGNGANKKVELSRMSSTKSSGSESDRSERPVLVRQSTFIKEAPSPTLRRKLEESA
Sbjct: 2401 LNQMNNGNGANKKVELSRMSSTKSSGSESDRSERPVLVRQSTFIKEAPSPTLRRKLEESA 2460

Query: 2461 SFESLSPSSRPASPTRSQAQTPVLSPSLPDMSLSTHSSVQAGGWRKLPPNLSPTIEYNDG 2520
            SFESLSPSSRPASPTRSQAQTPVLSPSLPDMSLSTHSSVQAGGWRKLPPNLSPTIEYNDG
Sbjct: 2461 SFESLSPSSRPASPTRSQAQTPVLSPSLPDMSLSTHSSVQAGGWRKLPPNLSPTIEYNDG 2520

Query: 2521 RPAKRHDIARSHSESPSRLPINRSGTWKREHSKHSSSLPRVSTWRRTGSSSSILSASSES 2580
            RPAKRHDIARSHSESPSRLPINRSGTWKREHSKHSSSLPRVSTWRRTGSSSSILSASSES
Sbjct: 2521 RPAKRHDIARSHSESPSRLPINRSGTWKREHSKHSSSLPRVSTWRRTGSSSSILSASSES 2580

Query: 2581 SEKAKSEDEKHVNSISGTKQSKENQVSAKGTWRKIKENEFSPTNSTSQTVSSGATNGAES 2640
            SEKAKSEDEKHVNSISGTKQSKENQVSAKGTWRKIKENEFSPTNSTSQTVSSGATNGAES
Sbjct: 2581 SEKAKSEDEKHVNSISGTKQSKENQVSAKGTWRKIKENEFSPTNSTSQTVSSGATNGAES 2640

Query: 2641 KTLIYQMAPAVSKTEDVWVRIEDCPINNPRSGRSPTGNTPPVIDSVSEKANPNIKDSKDN 2700
            KTLIYQMAPAVSKTEDVWVRIEDCPINNPRSGRSPTGNTPPVIDSVSEKANPNIKDSKDN
Sbjct: 2641 KTLIYQMAPAVSKTEDVWVRIEDCPINNPRSGRSPTGNTPPVIDSVSEKANPNIKDSKDN 2700

Query: 2701 QAKQNVGNGSVPMRTVGLENRLNSFIQVDAPDQKGTEIKPGQNNPVPVSETNESSIVERT 2760
            QAKQNVGNGSVPMRTVGLENRLNSFIQVDAPDQKGTEIKPGQNNPVPVSETNESSIVERT
Sbjct: 2701 QAKQNVGNGSVPMRTVGLENRLNSFIQVDAPDQKGTEIKPGQNNPVPVSETNESSIVERT 2760

Query: 2761 PFSSSSSSKHSSPSGTVAARVTPFNYNPSPRKSSADSTSARPSQIPTPVNNNTKKRDSKT 2820
            PFSSSSSSKHSSPSGTVAARVTPFNYNPSPRKSSADSTSARPSQIPTPVNNNTKKRDSKT
Sbjct: 2761 PFSSSSSSKHSSPSGTVAARVTPFNYNPSPRKSSADSTSARPSQIPTPVNNNTKKRDSKT 2820

Query: 2821 DSTESSGTQSPKRHSGSYLVTSV 2843
            DSTESSGTQSPKRHSGSYLVTSV
Sbjct: 2821 DSTESSGTQSPKRHSGSYLVTSV 2843


>gi|5031587 adenomatosis polyposis coli 2 [Homo sapiens]
          Length = 2303

 Score =  873 bits (2255), Expect = 0.0
 Identities = 498/1007 (49%), Positives = 661/1007 (65%), Gaps = 93/1007 (9%)

Query: 2   AAASYDQLLKQVEALKMENSNLRQELEDNSNHLTKLETEASNMKEVLKQLQGSIEDEA-- 59
           + A Y+QL++QVEALK ENS+LRQEL DNS+HL+KLETE S MKEVLK LQG +E EA  
Sbjct: 4   SVAPYEQLVRQVEALKAENSHLRQELRDNSSHLSKLETETSGMKEVLKHLQGKLEQEARV 63

Query: 60  MASSGQIDLLERLKELNLDSSNFPGVKLRSKMSLRSYGSREGSVSSRSGECSPVPMGSFP 119
           + SSGQ ++LE+LK L +D ++   +K +         +     ++R+ E SPV      
Sbjct: 64  LVSSGQTEVLEQLKALQMDITSLYNLKFQPP-------TLGPEPAARTPEGSPVHGSGPS 116

Query: 120 RRGFVNGSRESTGYLEELEKERSLLLADLDKEEKEKDWYYAQLQNLTKRIDSLPLTEN-F 178
           +  F   SR +   LEEL++ER  LL +++KEEKEK WYY+QLQ L+KR+D LP  E  F
Sbjct: 117 KDSFGELSRATIRLLEELDRERCFLLNEIEKEEKEKLWYYSQLQGLSKRLDELPHVETQF 176

Query: 179 SLQTDMTRRQLEYEARQIRVAMEEQLGTCQDMEKRAQRRIARIQQIEKDILRIRQLLQSQ 238
           S+Q D+ R+QLE+EA+ IR  MEE+ GT  +M +RAQ R +R++QI+K++L         
Sbjct: 177 SMQMDLIRQQLEFEAQHIRSLMEERFGTSDEMVQRAQIRASRLEQIDKELLE-------- 228

Query: 239 ATEAERSSQNKHETGSHDAERQNEGQGVGEINMATSGNGQGSTTRMDHETASVLSSSSTH 298
                          + D  +Q E Q +  +           +  +D +  + + +    
Sbjct: 229 ---------------AQDRVQQTEPQALLAVK----------SVPVDEDPETEVPTHPED 263

Query: 299 SAPRRLTSHLGTKVEMVYSLLSMLGTHDKDDMSRTLLAMSSSQDSCISMRQSGCLPLLIQ 358
             P+   S    KVE+V+ LLSML T D++D +RTLLAMSSS +SC++MR+SGCLPLL+Q
Sbjct: 264 GTPQPGNS----KVEVVFWLLSMLATRDQEDTARTLLAMSSSPESCVAMRRSGCLPLLLQ 319

Query: 359 LLHGNDKDS---VLLGNSRGSKEARARASAALHNIIHSQPDDKRGRREIRVLHLLEQIRA 415
           +LHG +  +        + G+K+AR RA+AALHNI+ SQPD    R+E+RVLH+LEQIRA
Sbjct: 320 ILHGTEAAAGGRAGAPGAPGAKDARMRANAALHNIVFSQPDQGLARKEMRVLHVLEQIRA 379

Query: 416 YCETCWEWQEAHEPGMDQD-KNPMPAPVEHQICPAVCVLMKLSFDEEHRHAMNELGGLQA 474
           YCETCW+W +A + G +       P P+E QIC A C +MKLSFDEE+R AMNELGGLQA
Sbjct: 380 YCETCWDWLQARDGGPEGGGAGSAPIPIEPQICQATCAVMKLSFDEEYRRAMNELGGLQA 439

Query: 475 IAELLQVDCEMYGLTNDHYSITLRRYAGMALTNLTFGDVANKATLCSMKGCMRALVAQLK 534
           +AELLQVD EM+ +T D  ++ LRRYAGM LTNLTFGDVANKATLC+ +GCM A+VAQL 
Sbjct: 440 VAELLQVDYEMHKMTRDPLNLALRRYAGMTLTNLTFGDVANKATLCARRGCMEAIVAQLA 499

Query: 535 SESEDLQQVIASVLRNLSWRADVNSKKTLREVGSVKALMECALEVKKESTLKSVLSALWN 594
           S+SE+L QV++S+LRNLSWRAD+NSKK LRE GSV AL++C L   KESTLKSVLSALWN
Sbjct: 500 SDSEELHQVVSSILRNLSWRADINSKKVLREAGSVTALVQCVLRATKESTLKSVLSALWN 559

Query: 595 LSAHCTENKADICAVDGALAFLVGTLTYRSQTNTLAIIESGGGILRNVSSLIATNEDHRQ 654
           LSAH TENKA IC VDGAL FLV TLTY+ Q+N+LAIIESGGGILRNVSSL+AT ED+RQ
Sbjct: 560 LSAHSTENKAAICQVDGALGFLVSTLTYKCQSNSLAIIESGGGILRNVSSLVATREDYRQ 619

Query: 655 ILRENNCLQTLLQHLKSHSLTIVSNACGTLWNLSARNPKDQEALWDMGAVSMLKNLIHSK 714
           +LR++NCLQTLLQHL SHSLTIVSNACGTLWNLSAR+ +DQE LWD+GAV ML+NL+HSK
Sbjct: 620 VLRDHNCLQTLLQHLTSHSLTIVSNACGTLWNLSARSARDQELLWDLGAVGMLRNLVHSK 679

Query: 715 HKMIAMGSAAALRNLMANRPAKYK-DANIMSPGSSLPSLHVRKQKALEAELDAQHLSETF 773
           HKMIAMGSAAALRNL+A+RPAK++  A  +SPGS +PSL+VRKQ+ALEAELDA+HL++  
Sbjct: 680 HKMIAMGSAAALRNLLAHRPAKHQAAATAVSPGSCVPSLYVRKQRALEAELDARHLAQAL 739

Query: 774 DNIDNLSPKASHRSKQ------RHKQSLYGDYVFDTNRHDDNRSDN-----FNTG----- 817
           ++++   P A+  + +      RH   L  DY  D+   DD+ + +       TG     
Sbjct: 740 EHLEKQGPPAAEAATKKPLPPLRHLDGLAQDYASDSGCFDDDDAPSSLAAAAATGEPASP 799

Query: 818 ---NMTVLSPYLNTTVLPSSSSSRGSLDSSRSEKDRSLERERGIGLGNYHPATENPGTSS 874
              ++ + SP+L    L  +  +R       +EKD S E                   ++
Sbjct: 800 AALSLFLGSPFLQGQALARTPPTRRG--GKEAEKDTSGE----------------AAVAA 841

Query: 875 KRGLQISTTAAQIAKVMEEVSAIHTSQEDRSSGSTTELHCVTDERNALRRSSAAHTHSNT 934
           K   +++   A+I +++E++SA+HTS +D  S S+ +           +  S        
Sbjct: 842 KAKAKLALAVARIDQLVEDISALHTSSDDSFSLSSGDPGQEAPREGRAQSCSPCRGPEG- 900

Query: 935 YNFTKSENSNRTCSMPYAKLEYKRSSNDSLNSVSSSDGYGKRGQMKP 981
               + E  +R   +   K  +   SNDSLNS S+SDGY  R  M P
Sbjct: 901 ---GRREAGSRAHPLLRLKAAHASLSNDSLNSGSASDGYCPREHMLP 944



 Score =  210 bits (534), Expect = 2e-53
 Identities = 168/463 (36%), Positives = 229/463 (49%), Gaps = 67/463 (14%)

Query: 1222 SSNAKRQNQLHPSSAQSRSGQPQKAATCKVSSINQETIQTYCVEDTPICFSRCSSLSSLS 1281
            S  A++Q  L    A   S  P+K A   +S +  + +Q    ++ P+  SRCSSLSSLS
Sbjct: 1022 SPGARKQAWL---PADHLSKVPEKLAAAPLS-VASKALQKLAAQEGPLSLSRCSSLSSLS 1077

Query: 1282 SAEDEIGCNQTTQEADSANTLQIAEIKEKIGTRSAE-DPVSEVPAVSQHPRTKSS--RLQ 1338
            SA    G    ++  D  ++    E  E+ G   AE D     P  +  P    +  R +
Sbjct: 1078 SA----GRPGPSEGGDLDDSDSSLEGLEEAGPSEAELDSTWRAPGATSLPVAIPAPRRNR 1133

Query: 1339 GSSLSSESARHKAVEFSSGAKSPSKSGAQTPKSPPEHYVQETPLMFSRCTSVSSLDSFES 1398
            G  L  E A                    TP S  E+YVQETPL+ SRC+SVSSL SFES
Sbjct: 1134 GRGLGVEDA--------------------TPSSSSENYVQETPLVLSRCSSVSSLGSFES 1173

Query: 1399 RSIASSVQSEPCSGMVSGIISPSDLPDSPGQTMPPSRSKTPP--PPPQTAQTKREVPKNK 1456
             SIASS+ SEPCSG  SG ISPS+LPDSPGQTMPPSRSKTPP  P PQ        P   
Sbjct: 1174 PSIASSIPSEPCSGQGSGTISPSELPDSPGQTMPPSRSKTPPLAPAPQG-------PPEA 1226

Query: 1457 APTAEKRESGPKQAAVNAAVQRVQVLP---DADTLLHFATESTPDGFSCSSSLSALSLDE 1513
               + + ES  K+    A  +    LP   DA + + F  E   + FSC+SSLSAL+L E
Sbjct: 1227 TQFSLQWESYVKRFLDIADCRERCRLPSELDAGS-VRFTVEKPDENFSCASSLSALALHE 1285

Query: 1514 PFIQKDVELRIMPPVQENDNGNETESEQPKESNENQEKEAEKTIDSEKDLLDDSDDDDIE 1573
             ++Q+DVELR++P       G    +      +  +E+    T    +     + D ++E
Sbjct: 1286 HYVQQDVELRLLPSACPERGGGAGGAGLHFAGHRRREEGPAPTGSRPR----GAADQELE 1341

Query: 1574 ILEECIISAMPTKSSRKAKKPAQTASKLPPPVARKPSQLPVYKLLPSQNRLQPQKHVSFT 1633
            +L EC+ +A+P +  +        AS L P   R+   +PVY L+P+    Q        
Sbjct: 1342 LLRECLGAAVPARLRK-------VASALVP--GRRALPVPVYMLVPAPAPAQ-------- 1384

Query: 1634 PGDDMPRVYCVEGTPINFSTATSLSDLTIESPPNELAAGEGVR 1676
              +D       EGTP+NFS+A SLSD T++ PP +   G   R
Sbjct: 1385 --EDDSCTDSAEGTPVNFSSAASLSDETLQGPPRDQPGGPAGR 1425



 Score =  188 bits (477), Expect = 7e-47
 Identities = 273/998 (27%), Positives = 410/998 (41%), Gaps = 208/998 (20%)

Query: 1825 DKLPNNEDRVRGSFAFDSPHHYTPIEGTPYCFSRNDSLSSLDFDDDDVDLSREKAELRKA 1884
            DK  +   R RG  A  S    TP E   YCF  NDS                       
Sbjct: 1478 DKDGSKPGRTRGDGALQSLCLTTPTEEAVYCFYGNDS----------------------- 1514

Query: 1885 KENKESEAKVTSHTELTSNQQSANKTQAIAKQPINRGQPKPILQKQSTFPQSSKDIPDRG 1944
             E   + A   +H           +T AI +    R +P+   +K++  P  +       
Sbjct: 1515 DEEPPAAAPTPTH----------RRTSAIPRA-FTRERPQG--RKEAPAPSKAAPAAPPP 1561

Query: 1945 AATDEKLQNFAIENTPVCFSHNSSLSSLSDIDQENNNKENEPIKETEPPDSQGEPSKPQA 2004
            A T   L     + TP C+S +SS SSLS         E EP   +EPP       +P  
Sbjct: 1562 ARTQPSL---IADETPPCYSLSSSASSLS---------EPEP---SEPPAVHPRGREPAV 1606

Query: 2005 SGYAPKSFHVEDTPVCFSRNSSLSSLSIDSEDDLLQECISSAMPKKKKP-SRLKGDNEKH 2063
            +         +D      R+SS S  + +   +LLQ CISSA+P+++ P S L+    + 
Sbjct: 1607 T---------KDPGPGGGRDSSPSPRAAE---ELLQRCISSALPRRRPPVSGLR----RR 1650

Query: 2064 SPRNMGGILGEDLTLDLKDIQRPDSEHGLSPDSENFDWKAIQEGANSIVSSLHQAAAAAC 2123
             PR     L E      ++     +    + D ++ +W+AIQEGANSIV+ LHQAAAA  
Sbjct: 1651 KPRATR--LDERPAEGSRERGEEAAGSDRASDLDSVEWRAIQEGANSIVTWLHQAAAA-- 1706

Query: 2124 LSRQASSDSDSILSLKSGISLGS----PFHLTPDQEEKPFTSNKGPRILKPGEKSTLETK 2179
             +R+ASS+SDSILS  SG+S+GS    P H    Q E    S + P      EK    + 
Sbjct: 1707 -TREASSESDSILSFVSGLSVGSTLQPPKHRKGRQAEGEMGSARRP------EKRGAASV 1759

Query: 2180 KIESESKGIKGGKKVYKSLITGKVRSNSEISGQMKQPLQANMPSISRGRTMIHIPG---- 2235
            K     +   G +K                  +  Q     +P++ RGRT+I++P     
Sbjct: 1760 KTSGSPRSPAGPEK-----------------PRGTQKTTPGVPAVLRGRTVIYVPSPAPR 1802

Query: 2236 --VRNSSSSTSPVSKKGPP-LKTPA--SKSPSEGQTATTS-PRGAKPSVKSELSPVARQT 2289
               + +    +   K  PP L  PA  +K PS GQ  + S  R AK S  + LS   R  
Sbjct: 1803 AQPKGTPGPRATPRKVAPPCLAQPAAPAKVPSPGQQRSRSLHRPAKTSELATLSQPPRSA 1862

Query: 2290 SQIGGSSKAPSRSGSRDSTPSRPAQQPLSRPIQSPGRNSISPGRNGISPPNKLSQLPRTS 2349
            +     +K PS S S+ S    PA QPL R      R  ++     +  P   S +P+T 
Sbjct: 1863 TPPARLAKTPSSSSSQTS----PASQPLPRK-----RPPVTQAAGALPGPG-ASPVPKTP 1912

Query: 2350 SPSTASTKSSGSGKMSYTSPGRQMSQQNLTKQTGLSKNASSIPRSESASKGLNQMNNGNG 2409
            + +  + +       +  SP R    Q   ++ G    A ++P  E   +G      G G
Sbjct: 1913 ARTLLAKQHK-----TQRSPVRIPFMQRPARR-GPPPLARAVP--EPGPRGRAGTEAGPG 1964

Query: 2410 A-NKKVELSRMSSTKSSGSESDRSERPVLVRQSTFIKEAPSPTLRRKLEESASFESLSPS 2468
            A   ++ L R++S  SSGSES  S+R    RQ TFIKE  SP LRR+  E +S ES + +
Sbjct: 1965 ARGGRLGLVRVASALSSGSES--SDRSGFRRQLTFIKE--SPGLRRRRSELSSAESAASA 2020

Query: 2469 SRPASPTRSQAQTPVL---SPSLPDMSLSTHSSVQAGGWRKLPPNLSPTIEYNDGRPAKR 2525
             + ASP R +   P +   S    ++  +          R+ PP   P+      RPA+ 
Sbjct: 2021 PQGASPRRGRPALPAVFLCSSRCEELRAAPRQGPAPA--RQRPPAARPS---PGERPAR- 2074

Query: 2526 HDIARSHSESPSRLPINRSGTWKREHSKHSSSLPRVSTWRRTGSSSSILSASSESSEKAK 2585
                R+ SESPSRLP+ R+   + E  K  +SLP +S  RR   +     AS++++ ++ 
Sbjct: 2075 ----RTTSESPSRLPV-RAPAARPETVKRYASLPHISVARRPDGAVPAAPASADAARRSS 2129

Query: 2586 SEDEKHVNSISGTKQSKENQVSAKG-TWRKIKENEFSPTNSTSQTVSSGATNGAESKTLI 2644
              + + +            +V+A G TWR+I++ +      ++   ++    G+  +   
Sbjct: 2130 DGEPRPL-----------PRVAAPGTTWRRIRDEDVPHILRSTLPATALPLRGSTPEDA- 2177

Query: 2645 YQMAPAVSKTEDVWVRIEDCPINNPRSGRSPTGNT--PPVIDSVSEKANPNIKDSKDNQA 2702
                P   KT D  V+ E+       S  SP+  T  PP   +  + +         + A
Sbjct: 2178 -PAGPPPRKTSDAVVQTEEVAAPKTNSSTSPSLETREPPGAPAGGQLSLLGSDVDGPSLA 2236

Query: 2703 KQNVGNGSVPMRTVGLENRLNSFIQVDAPDQKGTEIKPGQNNPVPVSETNESSIVERTPF 2762
            K  +   S P    GL   +  F                                     
Sbjct: 2237 KAPI---SAPFVHEGLGVAVGGF------------------------------------- 2256

Query: 2763 SSSSSSKHSSPSGTVAARVTPFNYNPSPRKSSADSTSA 2800
                +S+H SPS   +ARV PFNY PSP   +A + SA
Sbjct: 2257 ---PASRHGSPSR--SARVPPFNYVPSPMVVAATTDSA 2289



 Score = 36.2 bits (82), Expect = 0.47
 Identities = 44/176 (25%), Positives = 62/176 (35%), Gaps = 48/176 (27%)

Query: 1432 PPSRSKTPPPPPQTAQTKREVPK---NKAPTAEKRESGPKQAAVNAAVQRVQVLPDADTL 1488
            PP+ + TP     T +    +P+    + P   K    P +AA  A        P A T 
Sbjct: 1518 PPAAAPTP-----THRRTSAIPRAFTRERPQGRKEAPAPSKAAPAAP-------PPARTQ 1565

Query: 1489 LHFATESTPDGFSCSSSLSALSLDEPFIQKDVELRIMPPVQEND---NGNETESEQPKES 1545
                 + TP  +S SSS S+LS  EP     V  R   P    D    G    S  P+ +
Sbjct: 1566 PSLIADETPPCYSLSSSASSLSEPEPSEPPAVHPRGREPAVTKDPGPGGGRDSSPSPRAA 1625

Query: 1546 NENQEKEAEKTIDSEKDLLDDSDDDDIEILEECIISAMPTK----SSRKAKKPAQT 1597
                                       E+L+ CI SA+P +    S  + +KP  T
Sbjct: 1626 E--------------------------ELLQRCISSALPRRRPPVSGLRRRKPRAT 1655



 Score = 35.4 bits (80), Expect = 0.81
 Identities = 55/244 (22%), Positives = 90/244 (36%), Gaps = 44/244 (18%)

Query: 1177 IDYSLKYATDIPSSQKQSFSFSKSSSGQSSKTEHMSSSSENTSTPSSNAKRQ-NQLHPSS 1235
            ID  ++  + + +S   SFS S    GQ +  E  + S      P    +   ++ HP  
Sbjct: 854  IDQLVEDISALHTSSDDSFSLSSGDPGQEAPREGRAQSCSPCRGPEGGRREAGSRAHPLL 913

Query: 1236 AQSRSGQPQKAATCKVS--SINQETIQT-YCVEDTPICFSRCSSLSSLSSAEDEIGCNQ- 1291
                     KAA   +S  S+N  +    YC  +  +       L++L+S  ++  C Q 
Sbjct: 914  R-------LKAAHASLSNDSLNSGSASDGYCPREHML----PCPLAALASRREDPRCGQP 962

Query: 1292 ----------------TTQEADSANTLQIAEIKEKIGTRSAEDPVSEVPAVSQHPRTKSS 1335
                              +EA SA+         ++ T         VP +    R  + 
Sbjct: 963  RPSRLDLDLPGCQAEPPAREATSADA--------RVRTIKLSPTYQHVPLLEGASRAGAE 1014

Query: 1336 RLQGSSLSSESARHKAVEFSSGAKSPSKSGAQ----TPKSPPEHYVQETPLMFSRCTSVS 1391
             L G  +S  + +   +     +K P K  A       K+  +   QE PL  SRC+S+S
Sbjct: 1015 PLAGPGISPGARKQAWLPADHLSKVPEKLAAAPLSVASKALQKLAAQEGPLSLSRCSSLS 1074

Query: 1392 SLDS 1395
            SL S
Sbjct: 1075 SLSS 1078



 Score = 34.7 bits (78), Expect = 1.4
 Identities = 49/203 (24%), Positives = 87/203 (42%), Gaps = 45/203 (22%)

Query: 1871 DVDLSREKAELRKAKENKESEAKVTSHTELTSNQQSANKTQAIAK---QPINRGQPKPIL 1927
            D+DL   +AE   A+E   ++A+V +  +L+   Q     +  ++   +P+      P  
Sbjct: 968  DLDLPGCQAE-PPAREATSADARVRT-IKLSPTYQHVPLLEGASRAGAEPLAGPGISPGA 1025

Query: 1928 QKQSTFPQSS-KDIPDRGAAT-----DEKLQNFAIENTPVCFSHNSSLSSLSDI------ 1975
            +KQ+  P      +P++ AA       + LQ  A +  P+  S  SSLSSLS        
Sbjct: 1026 RKQAWLPADHLSKVPEKLAAAPLSVASKALQKLAAQEGPLSLSRCSSLSSLSSAGRPGPS 1085

Query: 1976 ---DQENNNKENEPIKETEPPDSQ--------GEPSKP-----------------QASGY 2007
               D ++++   E ++E  P +++        G  S P                  A+  
Sbjct: 1086 EGGDLDDSDSSLEGLEEAGPSEAELDSTWRAPGATSLPVAIPAPRRNRGRGLGVEDATPS 1145

Query: 2008 APKSFHVEDTPVCFSRNSSLSSL 2030
            +    +V++TP+  SR SS+SSL
Sbjct: 1146 SSSENYVQETPLVLSRCSSVSSL 1168


>gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens]
          Length = 1301

 Score = 94.7 bits (234), Expect = 1e-18
 Identities = 162/778 (20%), Positives = 287/778 (36%), Gaps = 37/778 (4%)

Query: 2063 HSPRNMGGILGEDLTLDLKDIQRPDSEHGLSPDSENFDWKAIQEGANSIVSSLHQAAAAA 2122
            +S  N  G  G D      D  + DS  G S DS + D       ++S  SS   ++ + 
Sbjct: 523  NSDSNGNGNNGND------DNDKSDSGKGKS-DSSDSDSSDSSNSSDSSDSSDSDSSDSN 575

Query: 2123 CLSRQASSDSDSILSLKSGISLGSPFHLTPDQEEKPFTSNKGPRILKPGEKSTLETKKIE 2182
              S   SSDSDS  S  S  S  S    + D  +   +S+         + S  E+   +
Sbjct: 576  SSSDSDSSDSDSSDSSDSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSKSDSSKSESDSSD 635

Query: 2183 SESKGIKGGKKVYKSLITGKVRSNSEISGQMKQPLQANMPSISRGRTMIHIPGVRNSS-S 2241
            S+SK          S        +S  S        ++    S      +     +SS S
Sbjct: 636  SDSKSDSSDSNSSDSSDNSDSSDSSNSSNSSDSSDSSDSSDSSSSSDSSNSSDSSDSSDS 695

Query: 2242 STSPVSKKGPPLKTPASKSPSEGQTATTSPRGAKPSVKSELSPVARQTSQIGGSSKAPSR 2301
            S S  S          S   S+   + +S   +  S  S  S  +  +S    SS +   
Sbjct: 696  SNSSESSDSSDSSDSDSSDSSDSSNSNSSDSDSSNSSDSSDSSNSSDSSDSSDSSNSSDS 755

Query: 2302 SGSRDSTPSRPAQQPLSRPIQSPGRNSISPGRNGISPPNKLSQLPRTSSPSTASTKSSGS 2361
            S S DS+ S  +         S   NS     +  S  +  S     SS S+ S+ SS S
Sbjct: 756  SDSSDSSNSSDSSDSSDSSDSSDSSNSSDSNDSSNSSDSSDSS---NSSDSSNSSDSSDS 812

Query: 2362 GKMSYTSPGRQMSQQNLTKQTGLSKNASSIPRSESASKGLNQMNNGNGANKKVELSRMSS 2421
               S +         N +  +  S ++ S   S+S+    +  +N + ++   + S  S 
Sbjct: 813  SDSSDSDSSNSSDSSNSSDSSDSSNSSDSSDSSDSSDGSDSDSSNRSDSSNSSDSSDSSD 872

Query: 2422 TKSSGSESDRSERPVLVRQSTFIKEAPSPTLRRKLEESASFESLSPSSRPASPTRSQAQT 2481
            + +S   SD S+      +S+   ++   +     + S S  S   S    S   S++  
Sbjct: 873  SSNSSDSSDSSDS----NESSNSSDSSDSSNSSDSDSSDSSNSSDSSDSSNSSDSSESSN 928

Query: 2482 PVLSPSLPDMSLSTHSSVQAGGWRKLPP-NLSPTIEYNDGRPAKRHDIARSHSESPSRLP 2540
               + +  D S S+ SS  +         N S +   +D   +   D + S + S S   
Sbjct: 929  SSDNSNSSDSSNSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSNSSDSSDSSNSSDSSDS 988

Query: 2541 INRSGTWKREHSKHSSSLPRVSTWRRTGSSSSILSASSESSEKAKSEDEKHVNSISGTKQ 2600
             + S +     S +SS            S SS  S SS SS+ + S D  + +  S +  
Sbjct: 989  SDSSDSSDSSDSSNSSD----------SSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSSD 1038

Query: 2601 SKENQVSAKGTWRKIKENEFSPTNSTSQTVSSGATNGAESKTLIYQMAPAVSKTEDVWVR 2660
            S ++  S+  +      N    ++S+  + SS +++ ++S         + S        
Sbjct: 1039 SSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSESSDSSDSSNSS---D 1095

Query: 2661 IEDCPINNPRSGRSPTGNTPPVIDSVSEKANPNIKDSKDNQAKQNVGNGSVPMRTVGLEN 2720
              D   ++  S  S + ++    DS +   + +  DS D+    N  + S    +    +
Sbjct: 1096 SSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSSDSSESSDSSD 1155

Query: 2721 RLNSFIQVDAPDQKGTEIKPGQNNPVPVSETNESS-------IVERTPFSSSSSSKHSSP 2773
              +S    D+ D   +      +N    S++++SS         + +  S SS S  SS 
Sbjct: 1156 SSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSD 1215

Query: 2774 SGTVAARVTPFNYNPSPRKS-SADSTSARPSQIPTPVNNNTKKRDSKTDSTESSGTQS 2830
            S   +      + + S   S S+DS+ +  S   +  ++++   DS +DS + S +QS
Sbjct: 1216 SSDSSDSSDSSDSSDSNESSDSSDSSDSSDSSNSSDSSDSSDSSDSTSDSNDESDSQS 1273



 Score = 89.7 bits (221), Expect = 4e-17
 Identities = 139/664 (20%), Positives = 247/664 (37%), Gaps = 49/664 (7%)

Query: 765  DAQHLSETFDNIDNLSPKASHRSKQRHKQSLYGDYVFDTNRHDDNR--SDNFNTGNMTVL 822
            D+   S++ D+ D+ S  +   S      S       +++   DN   SD+ N+ N +  
Sbjct: 609  DSSDSSDSSDSSDSKSDSSKSESDSSDSDSKSDSSDSNSSDSSDNSDSSDSSNSSNSSDS 668

Query: 823  SPYLNTTVLPSSSSSRGSLDSSRSEKDRSLERERGIGLGNYHPATENPGTSSKRGLQIST 882
            S   +++   SSS S  S DSS S               N   ++++  +S       S 
Sbjct: 669  SDSSDSSDSSSSSDSSNSSDSSDSSDS-----------SNSSESSDSSDSSDSDSSDSSD 717

Query: 883  TAAQIAKVMEEVSAIHTSQEDRSSGSTTELHCVTDERNALRRSSAAHTHSNTYNFTKSEN 942
            ++   +   +  ++  +S    SS S+      +D  N+   S ++ + +++ +   S++
Sbjct: 718  SSNSNSSDSDSSNSSDSSDSSNSSDSSDS----SDSSNSSDSSDSSDSSNSSDSSDSSDS 773

Query: 943  SNRTCSMPYAKLEYKRSSNDSLNSVSSSDGYGKRGQMKPSIESYSEDDESKFCSYGQYPA 1002
            S+ + S   +      +S+DS +S +SSD          S  S S+   S   S     +
Sbjct: 774  SDSSDSSNSSDSNDSSNSSDSSDSSNSSDSSNSSDSSDSSDSSDSDSSNSSDSSNSSDSS 833

Query: 1003 DLAHKIHSANHMDDNDGELDTPINYSLKYSDEQLNSGRQSPSQNERWARPKHIIEDEIKQ 1062
            D ++   S++  D +DG      N S   S    +S   S S N           D    
Sbjct: 834  DSSNSSDSSDSSDSSDGSDSDSSNRS--DSSNSSDSSDSSDSSNS---------SDSSDS 882

Query: 1063 SEQRQSRNQSTTYPVYTESTDDKHLKFQPHFGQQECVSPYRSRGANGSETNRVGSNHGIN 1122
            S+  +S N S +      S  D               S   S  +N S+++   SN   N
Sbjct: 883  SDSNESSNSSDSSDSSNSSDSD---------SSDSSNSSDSSDSSNSSDSSE-SSNSSDN 932

Query: 1123 QNVSQSLCQEDDYEDDKPTNYSERYSEEEQHEEEERPTNYSIKYNEEKRHVDQPIDYSLK 1182
             N S S    D  +    +N S+  +  +     +   + S   ++     D     S  
Sbjct: 933  SNSSDSSNSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSNSSDSSDSSNSSD-----SSD 987

Query: 1183 YATDIPSSQKQSFSFSKSSSGQSSKTEHMSSSSENTSTPSSNAKRQNQLHPSSAQSRSGQ 1242
             +    SS     S S  SS  S  ++  +SS  + S+ SSN+   +    SS  S S  
Sbjct: 988  SSDSSDSSDSSDSSNSSDSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSSDSSDSSDSSD 1047

Query: 1243 PQKAATCKVSSINQETIQTYCVEDTPICFSRCSSLSSLSSAEDEIGCNQTTQEADSANTL 1302
               ++    SS + ++  +    D+    S  S  S  S + D    + ++  +DS+++ 
Sbjct: 1048 SSDSSDSSNSSDSSDSSDSSDSSDS----SDSSDSSDSSESSDSSDSSNSSDSSDSSDSS 1103

Query: 1303 QIAEIKEKIGTRSAEDPVSEVPAVSQHPRTKSSRLQGSSLSSESARHKAVEFSSGAKSPS 1362
              ++  +   +  + D  +   +      + SS    SS SS+S+       SS +   S
Sbjct: 1104 DSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSSDSSESSDSSDSSDSSDSS 1163

Query: 1363 KSGAQTPKSPPEHYVQETPLMFSRCTSVSSLDSFESRSIASSVQSEPCSGMVSGIISPSD 1422
             S   +  S        +    S  +S SS  S  S S  SS  S+  S   S     SD
Sbjct: 1164 DSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSD--SSDSSDSSDSSD 1221

Query: 1423 LPDS 1426
              DS
Sbjct: 1222 SSDS 1225



 Score = 89.4 bits (220), Expect = 5e-17
 Identities = 220/1170 (18%), Positives = 405/1170 (34%), Gaps = 90/1170 (7%)

Query: 1662 IESPPNELAAGEGVRGGAQSGEFEKRDTIPT-EGRSTDEAQGGKTSSVTIPELDDNKAEE 1720
            I S  N     E   G  +    +  D  P+  G   DE +G           DD   E 
Sbjct: 217  INSKRNGTKEAEVTPGTGEDAGLDNSDGSPSGNGADEDEDEGSG---------DDEDEEA 267

Query: 1721 GDILAECINSAMPKGKSHKPFRVKKIMDQVQQASASSSAPNKNQLDGKKKKPTSPVKPIP 1780
            G+      NS   +G+ H         +    +S   ++ +K   D + K+        P
Sbjct: 268  GNGKDSSNNSKGQEGQDHGK-------EDDHDSSIGQNSDSKEYYDPEGKED-------P 313

Query: 1781 QNTEYRTRVRKNADSKNNLNAERVFSDNKDSKKQNLKNNSKVFNDKLPNNEDRVRGSFAF 1840
             N     +  K+ ++   +  +      +D++K N + + +V N     +E    G    
Sbjct: 314  HNEVDGDKTSKSEENSAGIPEDNGSQRIEDTQKLNHRESKRVENRITKESETHAVGK--- 370

Query: 1841 DSPHHYTPIEGTPYCFSRNDSLSSLDFDDDDVDLSREKAELRKAKENKESEAKVTSHTEL 1900
             S      I+G P   +RN              +++E  +  + KE+K     +     +
Sbjct: 371  -SQDKGIEIKG-PSSGNRN--------------ITKEVGKGNEGKEDKGQHGMILGKGNV 414

Query: 1901 TSNQQSANKTQAIAKQPINRGQPKPILQKQSTFPQSSKDIPDRGAATDEKLQNFAIENTP 1960
             +  +  N      + P  + +P   +   +T   S+ D  D     D+ +Q     + P
Sbjct: 415  KTQGEVVN-----IEGPGQKSEPGNKVGHSNTGSDSNSDGYDSYDFDDKSMQG----DDP 465

Query: 1961 VCFSHNSSLSSLSDIDQENNNKENEPIKETEPPDSQGEPSKPQASGYAPKSFHVEDTPVC 2020
                 NSS  S  + D  + +  N   +     +S  + SK   +G   K    +D+   
Sbjct: 466  -----NSSDESNGNDDANSESDNNSSSRGDASYNS--DESKDNGNGSDSKGAEDDDSDST 518

Query: 2021 FSRNSSLSSLSIDSEDDLLQECISSAMPKKKKPSRLKGDNEKHSPRNMGGILGEDLTLDL 2080
               N+S S+ + ++ +D   +   S   K         D+   S  +         +   
Sbjct: 519  SDTNNSDSNGNGNNGNDDNDKS-DSGKGKSDSSDSDSSDSSNSSDSSDSSDSDSSDSNSS 577

Query: 2081 KDIQRPDSEHGLSPDSENFDWKAIQEGANSIVSSLHQAAAAACLSRQASSDSDSILSLKS 2140
             D    DS+   S DS++ D     + ++S  SS    ++ +  S+  SS S+S  S   
Sbjct: 578  SDSDSSDSDSSDSSDSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSKSDSSKSESDSS--- 634

Query: 2141 GISLGSPFHLTPDQEEKPFTSNKGPRILKPGEKSTLETKKIESESKGIKGGKKVYKSLIT 2200
                        D + K  +S+           S+  +    S             S   
Sbjct: 635  ------------DSDSKSDSSDSNSSDSSDNSDSSDSSNSSNSSDSSDSSDSSDSSSSSD 682

Query: 2201 GKVRSNSEISGQMKQPLQANMPSISRGRTMIHIPGVRNSSSSTSPVSKKGPPLKTPASKS 2260
                S+S  S       +++  S S            NS+SS S  S       +  S  
Sbjct: 683  SSNSSDSSDSSDSSNSSESSDSSDSSDSDSSDSSDSSNSNSSDSDSSNSSDSSDSSNSSD 742

Query: 2261 PSEGQTATTSPRGAKPSVKSELSPVARQTSQIGGSSKAPSRSGSRDSTPSRPAQQPLSRP 2320
             S+   ++ S   +  S  S  S     +S    SS +   S S DS  S  +       
Sbjct: 743  SSDSSDSSNSSDSSDSSDSSNSS----DSSDSSDSSDSSDSSNSSDSNDSSNSSDSSDSS 798

Query: 2321 IQSPGRNSISPGRNGISPPNKLSQLPRTSSPSTASTKSSGSGKMSYTSPGRQMSQQNLTK 2380
              S   NS     +  S  +  S     SS S+ S+ SS S   S +S     S  + + 
Sbjct: 799  NSSDSSNSSDSSDSSDSSDSDSSN----SSDSSNSSDSSDSSNSSDSSDSSDSSDGSDSD 854

Query: 2381 QTGLSKNASSIPRSESASKGLNQMNNGNGANKKVELSRMSSTKSSGSESDRSERPVLVRQ 2440
             +  S +++S   S+S+    +  ++ +  + +   S  SS  S+ S+SD S+       
Sbjct: 855  SSNRSDSSNSSDSSDSSDSSNSSDSSDSSDSNESSNSSDSSDSSNSSDSDSSDSSNSSDS 914

Query: 2441 STFIKEAPSPTLRRKLEESASFESLSPSSRPASPTRSQAQTPVLSPSLPDMSLSTHSSVQ 2500
            S     + S       + S S +S + S    S   S +     S    + S S+ S+  
Sbjct: 915  SDSSNSSDSSESSNSSDNSNSSDSSNSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSNSS 974

Query: 2501 AGGWRKLPPNLSPTIEYNDGRPAKRHDIARSHSESPSRLPINRSGTWKREHSKHSSSLPR 2560
                     + S + + +D   +     +   S+S      + S          +SS   
Sbjct: 975  DSSDSSNSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSNSSDSSNSSDSSNSSDSS 1034

Query: 2561 VSTWRRTGSSSSILSASSESSEKAKSEDEKHVNSISGTKQSKENQVSAKGTWRKIKENEF 2620
             S+     S SS  S SS+SS  + S D    +  S +  S ++  S++ +      N  
Sbjct: 1035 DSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSESSDSSDSSNSS 1094

Query: 2621 SPTNSTSQTVSSGATNGAESKTLIYQMAPAVSKTEDVWVRIEDCPINNPRSGRSPTGNTP 2680
              ++S+  + SS +++ ++S         + S          D   ++  S  S + ++ 
Sbjct: 1095 DSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSSDSSESSDSS 1154

Query: 2681 PVIDSVSEKANPNIKDSKDNQAKQNVGNGSVPMRTVGLENRLNSFIQVDAPDQKGTEIKP 2740
               DS     + +  DS D+    N  + S    +    +  +S    D+ D   +    
Sbjct: 1155 DSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSS 1214

Query: 2741 GQNNPVPVSETNESSIVERTPFSSSSSSKHSSPSGTVAARVTPFNYNPSPRKSSADSTSA 2800
              ++    S++++SS    +  SS SS    S + + ++       +     S++DS   
Sbjct: 1215 DSSDSSDSSDSSDSSDSNESSDSSDSSDSSDSSNSSDSSD------SSDSSDSTSDSNDE 1268

Query: 2801 RPSQIPTPVNNNTKKRDSKTDSTESSGTQS 2830
              SQ  +  N N    DS +DS  S    S
Sbjct: 1269 SDSQSKSG-NGNNNGSDSDSDSEGSDSNHS 1297



 Score = 88.6 bits (218), Expect = 8e-17
 Identities = 160/747 (21%), Positives = 283/747 (37%), Gaps = 39/747 (5%)

Query: 2095 DSENFDWKAIQ-EGANSIVSSLHQAAAAACLSRQASSDSDSILSLKSGISLGSPFHLTPD 2153
            DS +FD K++Q +  NS   S          +  A+S+SD+  S +   S  S      D
Sbjct: 451  DSYDFDDKSMQGDDPNSSDESNG--------NDDANSESDNNSSSRGDASYNS------D 496

Query: 2154 QEEKPFTSNKGPRILKPGEKSTLETKKIESESKGIKGGKKVYKSLITGKVRSNSEISGQM 2213
            + +     +           ST +T   +S   G  G     KS  +GK +S+S  S   
Sbjct: 497  ESKDNGNGSDSKGAEDDDSDSTSDTNNSDSNGNGNNGNDDNDKS-DSGKGKSDSSDSDSS 555

Query: 2214 KQPLQANMPSISRGRTMIHIPGVRNSSSSTSPVSKKGPPLKTPASKSPSEGQTATTSPRG 2273
                 ++    S   +        +SS S S  S       + +S S +   ++ +S   
Sbjct: 556  DSSNSSDSSDSSDSDSS----DSNSSSDSDSSDSDSSDSSDSDSSDSSNSSDSSDSSDSS 611

Query: 2274 AKPSVKSELSPVARQTSQIGGSSKAPSRSGSRDSTPSRPAQQPLSRPIQSPGRNSISPGR 2333
                        +  +     SS + S+S S DS  S  +    S    S   NS +   
Sbjct: 612  DSSDSSDSSDSKSDSSKSESDSSDSDSKSDSSDSNSSDSSDNSDS----SDSSNSSNSSD 667

Query: 2334 NGISPPNKLSQLPRTSSPSTASTKSSGSGKMSYTSPGRQMSQQNLTKQTGLSKNASSIPR 2393
            +  S  +  S     SS S+ S+ SS S   S +S     S  + +  +  S + SS   
Sbjct: 668  SSDSSDSSDSSSSSDSSNSSDSSDSSDSSNSSESSDSSDSSDSDSSDSSDSSNSNSSDSD 727

Query: 2394 SESASKGLNQMNNGNGANKKVELSRMSSTKSSGSE--SDRSERPVLVRQSTFIKEAPSPT 2451
            S ++S   +  N+ + ++     +   S+ SS S   SD S+       S     + S  
Sbjct: 728  SSNSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSND 787

Query: 2452 LRRKLEESASFESLSPSSRPASPTRSQAQTPVLSPSLPDMSLSTHSSVQAGGWRKLPPNL 2511
                 + S S  S S SS  +  + S   +   S +  D S S+ SS  +        + 
Sbjct: 788  SSNSSDSSDSSNS-SDSSNSSDSSDSSDSSDSDSSNSSDSSNSSDSSDSSNSSDS--SDS 844

Query: 2512 SPTIEYNDGRPAKRHDIARSHSESPSRLPINRSGTWKREHSKHSSSLPRVSTWRRTGSSS 2571
            S + + +D   + R D + S   S S    N S +     S  SS+    S      SS+
Sbjct: 845  SDSSDGSDSDSSNRSDSSNSSDSSDSSDSSNSSDSSDSSDSNESSNSSDSSD-----SSN 899

Query: 2572 SILSASSESSEKAKSEDEKHVNSISGTKQSKENQVSAKGTWRKIKENEFSPTNSTSQTVS 2631
            S  S SS+SS  + S D  + +  S +  S +N  S+  +      +    +NS+  + S
Sbjct: 900  SSDSDSSDSSNSSDSSDSSNSSDSSESSNSSDNSNSSDSSNSSDSSDSSDSSNSSDSSNS 959

Query: 2632 SGATNGAESKTLIYQMAPAVSKTEDVWVRIEDCPINNPRSGRSPTGNTPPVIDSVSEKAN 2691
            S ++N ++S       +   S + D      D   ++  S  S + N+    DS     +
Sbjct: 960  SDSSNSSDSSDSNSSDSSDSSNSSDS----SDSSDSSDSSDSSDSSNSSDSSDSSDSSDS 1015

Query: 2692 PNIKDSKDNQAKQNVGNGSVPMRTVGLENRLNSFIQVDAPDQKGTEIKPGQNNPVPVSET 2751
             N  DS ++    N  + S    +    +  +S    D+ +   +      ++    S++
Sbjct: 1016 SNSSDSSNSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDS 1075

Query: 2752 NESS-IVERTPFSSSSSSKHSSPSGTVAARVTPFNYNPSPRKSSADSTSARPSQIPTPVN 2810
            ++SS   E +  S SS+S  SS S   +      + + S   S + ++S       +  +
Sbjct: 1076 SDSSDSSESSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDS 1135

Query: 2811 NNTKKRDSKTDSTESSGTQSPKRHSGS 2837
            +++      +DS+ESS +      S S
Sbjct: 1136 SDSSNSSDSSDSSESSDSSDSSDSSDS 1162



 Score = 81.6 bits (200), Expect = 1e-14
 Identities = 141/775 (18%), Positives = 286/775 (36%), Gaps = 27/775 (3%)

Query: 805  RHDDNRSDNFNTGNMTVLSPYLNTTVLPSSSSSRGSLDSSRSEKDRSLERERGIGLGNYH 864
            + D + SD+ ++ N +  S   ++    S+SSS    DSS S+   S + +      +  
Sbjct: 546  KSDSSDSDSSDSSNSSDSSDSSDSDSSDSNSSSDS--DSSDSDSSDSSDSDSSDSSNSSD 603

Query: 865  PATENPGTSSKRGLQISTTAAQIAKVMEEVSAIHTSQE--DRSSGSTTELHCVTDERNAL 922
             +  +  + S      S + +  +K   + S   +  +  D +S  +++    +D  N+ 
Sbjct: 604  SSDSSDSSDSSDSSDSSDSKSDSSKSESDSSDSDSKSDSSDSNSSDSSDNSDSSDSSNSS 663

Query: 923  RRSSAAHTHSNTYNFTKSENSNRTCSMPYA---KLEYKRSSNDSLNSVSSSDGYGKRGQM 979
              S ++ +  ++ + + S++SN + S   +          S+DS +S SS          
Sbjct: 664  NSSDSSDSSDSSDSSSSSDSSNSSDSSDSSDSSNSSESSDSSDSSDSDSSDSSDSSNSNS 723

Query: 980  KPSIESYSEDDESKFCSYGQYPADLAHKIHSANHMDDNDGELDTPINYSLKYSD--EQLN 1037
              S  S S D  S   S     +D +   +S++  D +D    +  + S   SD  +  N
Sbjct: 724  SDSDSSNSSD--SSDSSNSSDSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSSDSSN 781

Query: 1038 SGRQSPSQNERWARPKHIIEDEIKQSEQRQSRNQSTTYPVYTESTDDKHLKFQPHFGQQE 1097
            S   + S N   +       D    S+   S + S +    +  + +             
Sbjct: 782  SSDSNDSSNSSDSSDSSNSSDSSNSSDSSDSSDSSDSDSSNSSDSSNSSDSSDSSNSSDS 841

Query: 1098 CVSPYRSRGANGSETNRVGSNHGINQNVSQSLCQEDDYEDDKPTNYSERYSEEEQHEEEE 1157
              S   S G++   +NR  S++  + + S       D  D   +N S   S+        
Sbjct: 842  SDSSDSSDGSDSDSSNRSDSSNSSDSSDSSDSSNSSDSSDSSDSNESSNSSDSSD----- 896

Query: 1158 RPTNYSIKYNEEKRHVDQPIDYSLKYATDIPSSQKQSFSFSKSSSGQSSKTEHMSSSSEN 1217
              +N S   + +  +     D     +++   S + S S   S+S  SS +   S SS++
Sbjct: 897  -SSNSSDSDSSDSSNSSDSSD-----SSNSSDSSESSNSSDNSNSSDSSNSSDSSDSSDS 950

Query: 1218 TSTPSSNAKRQNQLHPSSAQSRSGQPQKAATCKVSSINQETIQTYCVEDTPICFSRCSSL 1277
            +++  S+    +     S+ S S     ++    SS + ++  +    D+    S  S  
Sbjct: 951  SNSSDSSNSSDSSNSSDSSDSNSSDSSDSSNSSDSSDSSDSSDSSDSSDS----SNSSDS 1006

Query: 1278 SSLSSAEDEIGCNQTTQEADSANTLQIAEIKEKIGTRSAEDPVSEVPAVSQHPRTKSSRL 1337
            S  S + D    + ++  +DS+N+   ++  +   +  + D      + +    + SS  
Sbjct: 1007 SDSSDSSDSSNSSDSSNSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDS 1066

Query: 1338 QGSSLSSESARHKAVEFSSGAKSPSKSGAQTPKSPPEHYVQETPLMFSRCTSVSSLDSFE 1397
              SS SS+S+       SS +   S S   +  S        +    S  +S SS  S  
Sbjct: 1067 SDSSDSSDSSDSSDSSESSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDS 1126

Query: 1398 SRSIASSVQSEPCSGMVSGIIS-PSDLPDSPGQTMPPSRSKTPPPPPQTAQTKREVPKNK 1456
            S S  SS  S+  +   S   S  SD  DS   +     S +      +  +      + 
Sbjct: 1127 SDSSDSSDSSDSSNSSDSSDSSESSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDS 1186

Query: 1457 APTAEKRESGPKQAAVNAAVQRVQVLPDADTLLHFATESTPDGFSCSSSLSALSLDEPFI 1516
            + +++  +S     + +++           +    +++S+    S  SS S+ S D    
Sbjct: 1187 SDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSNESSDSSDSSDSSDS 1246

Query: 1517 QKDVELRIMPPVQENDNGNETESEQPKESNENQEKEAEKTIDSEKDLLDDSDDDD 1571
                +        ++ + +  ES+   +S       ++   DSE    + S  DD
Sbjct: 1247 SNSSDSSDSSDSSDSTSDSNDESDSQSKSGNGNNNGSDSDSDSEGSDSNHSTSDD 1301



 Score = 74.7 bits (182), Expect = 1e-12
 Identities = 149/751 (19%), Positives = 271/751 (36%), Gaps = 85/751 (11%)

Query: 827  NTTVLPSSSSSRGSLDSSRSEKDRSLERERGIGLGNYHPATENPGTSSKRGLQISTTAAQ 886
            N+  +P  + S+   D+ +     S   E  I        T   G S  +G++I   ++ 
Sbjct: 328  NSAGIPEDNGSQRIEDTQKLNHRESKRVENRI---TKESETHAVGKSQDKGIEIKGPSSG 384

Query: 887  IAKVMEEVSAIHTSQEDRSSGSTTELHCVTDERNALRRSSAAHTHSNTYNFT----KSEN 942
               + +EV   +  +ED+             +   +       T     N      KSE 
Sbjct: 385  NRNITKEVGKGNEGKEDKG------------QHGMILGKGNVKTQGEVVNIEGPGQKSEP 432

Query: 943  SNRTCSMPYAKLEYKRSSNDSLNSVSSSDGYGKRGQMKPSIESYSEDDESKFCSYGQYP- 1001
             N+               + +  S S+SDGY          +SY  DD+S     G  P 
Sbjct: 433  GNKV-------------GHSNTGSDSNSDGY----------DSYDFDDKSM---QGDDPN 466

Query: 1002 -ADLAHKIHSANHMDDNDGELDTPINYSLKYSDEQLNSGRQSPSQNERWARPKHIIEDEI 1060
             +D ++    AN   DN+       +Y+   SDE  ++G  S S+           ED+ 
Sbjct: 467  SSDESNGNDDANSESDNNSSSRGDASYN---SDESKDNGNGSDSKGA---------EDD- 513

Query: 1061 KQSEQRQSRNQSTTYPVYTESTDDKHLKFQPHFGQQECVSPYRSRGANGSETNRVGSNHG 1120
              S+     N S +        DD   K     G+ +      S  +N S+++    +  
Sbjct: 514  -DSDSTSDTNNSDSNGNGNNGNDDND-KSDSGKGKSDSSDSDSSDSSNSSDSSDSSDSDS 571

Query: 1121 INQNVSQSLCQEDDYEDDKPTNYSERYSEEEQHEEEERPTNYSIKYNEEKRHVDQPIDYS 1180
             + N S     + D  D   ++ S+  S +  +  +   ++ S   ++     D   D S
Sbjct: 572  SDSNSSS----DSDSSDSDSSDSSDSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSKSDSS 627

Query: 1181 LKYATDIPSSQKQSFSFSKSSSGQSSKTEHMSSSSENTSTPSSNAKRQNQLHPSSAQSRS 1240
                    S    S S SKS S  S+ ++   +S  + S+ SSN+   +    SS  S S
Sbjct: 628  -------KSESDSSDSDSKSDSSDSNSSDSSDNSDSSDSSNSSNSSDSSDSSDSSDSSSS 680

Query: 1241 GQPQKAATCKVSSINQETIQTYCVEDTPICFSRCSSLSSLSSAEDEIGCNQTTQEADSAN 1300
                 ++    SS +  + ++    D+    S  SS SS S++ D    N ++  +DS+N
Sbjct: 681  SDSSNSSDSSDSSDSSNSSESSDSSDSSDSDSSDSSDSSNSNSSDSDSSN-SSDSSDSSN 739

Query: 1301 TLQIAEIKEKIGTRSAEDPVSEVPAVSQHPRTKSSRLQGSSLSSESARHKAVEFSSGAKS 1360
            +   ++  +   +  + D      +      + SS    SS SS+S        SS + +
Sbjct: 740  SSDSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSNDSSNSSDSSDSSN 799

Query: 1361 PSKSGAQTPKSPPEHYVQETPLMFSRCTSVSSLDSFESRSIASSVQSEPCSGMVSGIISP 1420
             S S   +  S       ++    S  +S SS  S  S S  SS  S+   G  S   + 
Sbjct: 800  SSDSSNSSDSSDSSD-SSDSDSSNSSDSSNSSDSSDSSNSSDSSDSSDSSDGSDSDSSNR 858

Query: 1421 SDLPDSPGQTMPPSRSKTPPPPPQTAQTKREVPKNKAPTAEKRESGPKQAAVNAAVQRVQ 1480
            SD  +S   +     S +      +   +     + + ++   +S    ++ ++      
Sbjct: 859  SDSSNSSDSSDSSDSSNSSDSSDSSDSNESSNSSDSSDSSNSSDSDSSDSSNSSDSSDSS 918

Query: 1481 VLPDADTLLHFATESTPDGFSCSSSLSALSLDEPFIQKDVELRIMPPVQENDNGNETESE 1540
               D+      ++ S+ +  S  SS S+ S D        +         +D+ N ++S 
Sbjct: 919  NSSDSSE----SSNSSDNSNSSDSSNSSDSSDSSDSSNSSD-----SSNSSDSSNSSDSS 969

Query: 1541 QPKESNENQEKEAEKTIDSEKDLLDDSDDDD 1571
                S+ +    +  + DS  D  D SD  D
Sbjct: 970  DSNSSDSSDSSNSSDSSDS-SDSSDSSDSSD 999



 Score = 71.6 bits (174), Expect = 1e-11
 Identities = 133/659 (20%), Positives = 244/659 (37%), Gaps = 65/659 (9%)

Query: 765  DAQHLSETFDNIDNLSPKASHRSKQRHKQSLYGDYVFDTNRHDDNRSDNFNTGNMTVLSP 824
            D+ + SE+ D+ D+    +S  S   +  S   D     + +  + SD+ N+ + +  S 
Sbjct: 694  DSSNSSESSDSSDSSDSDSSDSSDSSNSNSSDSD-----SSNSSDSSDSSNSSDSSDSSD 748

Query: 825  YLNTTVLPSSSSSRGSLDSSRSEKDRSLERERGIGLGNYHPATENPGTSSKRGLQISTTA 884
              N++    SS S  S DSS S               N    + +   SS      +++ 
Sbjct: 749  SSNSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSNDSSNSSDSSDSSNSSDSSNSSD 808

Query: 885  AQIAKVMEEVSAIHTSQEDRSSGSTTELHCVTDERNALRRSSAAHTHSNTYNFTKSENSN 944
            +  +    +  + ++S    SS S+       D  N    SS +   S++ + + S++SN
Sbjct: 809  SSDSSDSSDSDSSNSSDSSNSSDSS-------DSSN----SSDSSDSSDSSDGSDSDSSN 857

Query: 945  RTCSMPYAKLEYKRSSNDSLNSVSSSDGYGKRGQMKPSIESYSEDDESKFCSYGQYPADL 1004
            R+ S          +S+DS +S  SS+          +  S S D      S     +D 
Sbjct: 858  RSDSS---------NSSDSSDSSDSSNSSDSSDSSDSNESSNSSDSSDSSNSSDSDSSDS 908

Query: 1005 AHKIHSANHMDDNDGELDTPINYSLKYSDEQLNSGRQSPSQNERWARPKHIIEDEIKQSE 1064
            ++   S++  + +D             S E  NS   S S +   +       D    S+
Sbjct: 909  SNSSDSSDSSNSSD-------------SSESSNSSDNSNSSDSSNSSDSSDSSDSSNSSD 955

Query: 1065 QRQSRNQSTTYPVYTESTDDKHLKFQPHFGQQECVSPYRSRGANGSETNRVGSNHGINQN 1124
               S + S +    ++S+D                S   S  +N S+++   S+   + +
Sbjct: 956  SSNSSDSSNS----SDSSDSN--------------SSDSSDSSNSSDSS--DSSDSSDSS 995

Query: 1125 VSQSLCQEDDYEDDKPTNYSERYSEEEQHEEEERPTNYSIKYNEEKRHVDQPIDYSLKYA 1184
             S       D  D   ++ S   S+     +    ++ S    +     D         +
Sbjct: 996  DSSDSSNSSDSSDSSDSSDSSNSSDSSNSSDSSNSSDSS----DSSDSSDSSDSSDSSDS 1051

Query: 1185 TDIPSSQKQSFSFSKSSSGQSSKTEHMSSSSENT-STPSSNAKRQNQLHPSSAQSRSGQP 1243
            +D  +S   S S   S S  SS +   S SSE++ S+ SSN+   +    SS  S S   
Sbjct: 1052 SDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSESSDSSDSSNSSDSSDSSDSSDSSDSSDS 1111

Query: 1244 QKAATCKVSSINQETIQTYCVEDTPICFSRCSSLSSLSSAEDEIGCNQTTQEADSANTLQ 1303
              ++    SS + ++  +    D+    S  S  S  S + D    + ++  +DS+++  
Sbjct: 1112 SDSSDSSDSSNSSDSSDSSDSSDSSDS-SNSSDSSDSSESSDSSDSSDSSDSSDSSDSSD 1170

Query: 1304 IAEIKEKIGTRSAEDPVSEVPAVSQHPRTKSSRLQGSSLSSESARHKAVEFSSGAKSPSK 1363
             ++  +   +  + D      +      + SS    SS SS+S+       SS +   S 
Sbjct: 1171 SSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSD 1230

Query: 1364 SGAQTPKSPPEHYVQETPLMFSRCTSVSSLDSFESRSIASSVQSEPCSGMVSGIISPSD 1422
            S   +  S        +    S  +S SS DS    +  S  QS+  +G  +G  S SD
Sbjct: 1231 SNESSDSSDSSDSSDSSNSSDSSDSSDSS-DSTSDSNDESDSQSKSGNGNNNGSDSDSD 1288



 Score = 60.5 bits (145), Expect = 2e-08
 Identities = 88/511 (17%), Positives = 190/511 (37%), Gaps = 19/511 (3%)

Query: 731  ANRPAKYKDANIMSPGSSLPSLHVRKQKALEAELDAQHLSETFDNIDNLSPKASHRSKQR 790
            +N  +   D++  S  S   +       +  ++ D+ + S++ ++ D+     S  S   
Sbjct: 785  SNDSSNSSDSSDSSNSSDSSNSSDSSDSSDSSDSDSSNSSDSSNSSDSSDSSNSSDSSDS 844

Query: 791  HKQSLYGDYVFDTNRHDDNRSDNFNTGNMTVLSPYLNTTVLPSSSSSRGSLDSSRSEKDR 850
               S   D          N SD+ ++ + +  S   +++    SS+S  S DSS S    
Sbjct: 845  SDSSDGSDSDSSNRSDSSNSSDSSDSSDSSNSSDSSDSSDSNESSNSSDSSDSSNSSDSD 904

Query: 851  SLERERGIGLGNYHPATENPGTSSKRGLQISTTAAQIAKVMEEVSAIHTSQEDRSSGSTT 910
            S +        +   ++++  +S+      S+ ++  +   +   + ++S    SS S+ 
Sbjct: 905  SSDSSNSSDSSDSSNSSDSSESSNSSDNSNSSDSSNSSDSSDSSDSSNSSDSSNSSDSSN 964

Query: 911  ELHCVTDERNALRRSSAAHTHSNTYNFTKSENSNRTCSMPYAKLEYKRSSNDSLNSVSSS 970
                 + + N+   S ++++  ++ +   S++S+ + S   +       S+DS NS  SS
Sbjct: 965  SSD--SSDSNSSDSSDSSNSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSNSSDSS 1022

Query: 971  DGYGKRGQMKPSIESYSEDDESKFCSYGQYPADLAHKIHSANHMDDNDGELDTPINYSLK 1030
            +          S  S S D      S     +  +     ++   D+    D+  +    
Sbjct: 1023 NSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSS 1082

Query: 1031 YSDEQLNSGRQSPSQNERWARPKHIIEDEIKQSEQRQSRNQSTTYPVYTESTDDKHLKFQ 1090
             S +  +S   S S +   +       D    S+   S N S +    ++S+D       
Sbjct: 1083 ESSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDS----SDSSD------- 1131

Query: 1091 PHFGQQECVSPYRSRGANGSETNRVGSNHGINQNVSQSLCQEDDYEDDKPTNYSERYSEE 1150
                  +      S  ++ S  +   S+   + + S S    D  +    +N S+  S +
Sbjct: 1132 ----SSDSSDSSNSSDSSDSSESSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSD--SSD 1185

Query: 1151 EQHEEEERPTNYSIKYNEEKRHVDQPIDYSLKYATDIPSSQKQSFSFSKSSSGQSSKTEH 1210
                 +   ++ S   ++     D         ++D   S   S S   S S  SS +  
Sbjct: 1186 SSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSNESSDSSDSSDSSD 1245

Query: 1211 MSSSSENTSTPSSNAKRQNQLHPSSAQSRSG 1241
             S+SS+++ +  S+    +    S +QS+SG
Sbjct: 1246 SSNSSDSSDSSDSSDSTSDSNDESDSQSKSG 1276


>gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens]
          Length = 2752

 Score = 94.4 bits (233), Expect = 1e-18
 Identities = 311/1595 (19%), Positives = 564/1595 (35%), Gaps = 198/1595 (12%)

Query: 1331 RTKSSRLQGSSLSSESARHKAVEFSSGAKSPSKSGAQTPKSPPEHYVQETPLMFSRCTSV 1390
            R++S   +G S S    R      SS  K+ S++  +  +S     ++++ +   R  S+
Sbjct: 703  RSRSLVRRGRSHSRTPQRRGRSGSSSERKNKSRTSQRRSRSNSSPEMKKSRISSRRSRSL 762

Query: 1391 SSLDSFESRSIA---SSVQSEPCSGMVSGIISPSDLPDSPGQTMPPSRSKTPPPPPQTAQ 1447
            SS  S     ++   S   S PC    S   +P     S G + P ++S+TPP   +++ 
Sbjct: 763  SSPRSKAKSRLSLRRSLSGSSPCPKQKSQ--TPPRRSRS-GSSQPKAKSRTPPRRSRSSS 819

Query: 1448 TKREVPKNKAPTAEKRESG---PKQAAVNAAVQRVQVLPDADTLLHFATESTPDGFSCSS 1504
            +     K+K P+ +   S    PK  +     Q     P A+         TP   SC  
Sbjct: 820  SPPPKQKSKTPSRQSHSSSSPHPKVKSGTPPRQGSITSPQAN-----EQSVTPQRRSCFE 874

Query: 1505 SLSALSLDEPFIQKDVELRIMPPVQENDNGN---ETESEQPKESNENQEKEAEKTIDSEK 1561
            S             D EL+   P + + +G+     +S  P   + ++    +  + +  
Sbjct: 875  S-----------SPDPELKSRTPSRHSCSGSSPPRVKSSTPPRQSPSRSSSPQPKVKAII 923

Query: 1562 DLLDDSDDDDIEILEECIISAMPTKSSRKAKKPAQTASKLPPPVARKPSQLPVYKLLPSQ 1621
                 S           + S    + SR     +   S+L P  +   S  P  K+ P  
Sbjct: 924  SPRQRSHSGSSSPSPSRVTSRTTPRRSRSVSPCSNVESRLLPRYSHSGSSSPDTKVKPET 983

Query: 1622 NRLQPQKHVSFTPGDDMPRVYCVEGTPINFSTATSLS--------DLTIESPPNELAAGE 1673
               Q         G   P       TP   S + S S        D  ++S P  L+   
Sbjct: 984  PPRQSHS------GSISPYPKVKAQTPPGPSLSGSKSPCPQEKSKDSLVQSCPGSLSLCA 1037

Query: 1674 GVRGGAQSGE-FEKRDTIPTEGRSTDEAQGGKTSSVTIPELDDNKAEEGDILAECINSAM 1732
            GV+     GE +    ++  +G+S  +      S  + PE+  + +E   + ++  +   
Sbjct: 1038 GVKSSTPPGESYFGVSSLQLKGQS--QTSPDHRSDTSSPEVRQSHSESPSLQSK--SQTS 1093

Query: 1733 PKG---KSHKPFRVKKIMDQVQQASASSSA-----PNKNQLDGKKKKPTSPVKPIPQNTE 1784
            PKG   +S  P         ++Q     SA        +    + +  +S    +  N+ 
Sbjct: 1094 PKGGRSRSSSPVTELASRSPIRQDRGEFSASPMLKSGMSPEQSRFQSDSSSYPTVDSNSL 1153

Query: 1785 YRTRVRKNADSKNNLNAERVFSDNKDSKKQNLKNNSKVFNDKLPNNEDRVRGSFAFDSPH 1844
                  + A+SK  +         +D+     +   K     +   +DR   S  F    
Sbjct: 1154 LGQSRLETAESKEKM----ALPPQEDATASPPRQKDKFSPFPV---QDRPESSLVFKDTL 1206

Query: 1845 HYTPIE-----GTPYCFSRNDSLSSLDFDDDDVDLSREKAELRKAKENKESEAKVTSHTE 1899
               P E      +P    +N +L +   D++ +++          ++++E   ++ SH  
Sbjct: 1207 RTPPRERSGAGSSPETKEQNSALPTSSQDEELMEV---------VEKSEEPAGQILSHLS 1257

Query: 1900 LTSNQQSANKTQAIAKQPINRGQPKPILQKQSTFPQSSKDIPDRGAA--------TDEKL 1951
                + S +  ++  +          + Q QS     + ++P   ++          ++L
Sbjct: 1258 SELKEMSTSNFESSPEVEERPAVSLTLDQSQSQASLEAVEVPSMASSWGGPHFSPEHKEL 1317

Query: 1952 QNFAIE----NTPVCFSHNSSLSSLSDIDQENNNKE--NEPI---KETEPPDSQGEPSKP 2002
             N  +      +P+ F ++  L +  +    +  KE  N P     ET+P     E S  
Sbjct: 1318 SNSPLRENSFGSPLEFRNSGPLGTEMNTGFSSEVKEDLNGPFLNQLETDPSLDMKEQS-T 1376

Query: 2003 QASGYAPKSFHVEDTPVC-FSRNSSLSSLSIDS--EDDLLQECISSAMPKKK-----KPS 2054
            ++SG++      +       S N S+SS  +D+       +   S++ P+ K      PS
Sbjct: 1377 RSSGHSSSELSPDAVEKAGMSSNQSISSPVLDAVPRTPSRERSSSASSPEMKDGLPRTPS 1436

Query: 2055 RLKGDNEKHSPRNMGGILG----EDLTLDLKDIQR-----------------------PD 2087
            R          R+  G          +  +KDI R                       P 
Sbjct: 1437 RRSRSGSSPGLRDGSGTPSRHSLSGSSPGMKDIPRTPSRGRSECDSSPEPKALPQTPRPR 1496

Query: 2088 SEHGLSPDSENFDWKAIQEGANSIVSSLHQAAAAACLSRQASSDSDSILSLKSGISLGSP 2147
            S    SP+  N      +E + S  S   +  A   L +++ S S   L +K   S    
Sbjct: 1497 SRSPSSPELNNKCLTPQRERSGSESSVDQKTVARTPLGQRSRSGSSQELDVKPSASPQER 1556

Query: 2148 FHLTPDQEEKPFTSNKGPRILKPGEKSTLETKKIESESKGIKGGKKVYKS--LITGKVRS 2205
                   + K  T     +  + G    +++K   S  +   G     K       + +S
Sbjct: 1557 SESDSSPDSKAKTRTPLRQRSRSGSSPEVDSKSRLSPRRSRSGSSPEVKDKPRAAPRAQS 1616

Query: 2206 NSEISGQMKQPLQANMPSISRGRTMIHIPGVRNSSSSTSPVSKKGPPLKTPASK----SP 2261
             S+ S + K P    +P  SR  +     G     SS++  S + PP    A +    SP
Sbjct: 1617 GSDSSPEPKAPAPRALPRRSRSGSSSKGRGPSPEGSSSTESSPEHPPKSRTARRGSRSSP 1676

Query: 2262 SEGQTATTSPRGAKPSVKSELSPVARQTSQIGGSSKAPSRSGSRDSTPSRPAQQP-LSRP 2320
                 + T PR        EL+  AR + +   +S +P    +R  TP R  + P +S P
Sbjct: 1677 EPKTKSRTPPRRRSSRSSPELTRKARLSRRSRSASSSPE---TRSRTPPRHRRSPSVSSP 1733

Query: 2321 IQSPGRNSISPGRNGISPPNK-LSQLPRTSSPSTASTKSSGS-GKMSYTSPGRQMSQQNL 2378
              +    S    R+  SP  K  S+  R+ SP     + S S  +   T   R+  +   
Sbjct: 1734 EPAEKSRSSRRRRSASSPRTKTTSRRGRSPSPKPRGLQRSRSRSRREKTRTTRRRDRSGS 1793

Query: 2379 TKQTGLSKNASSIPRSESASKGLNQMNNGNGANKKVELSRMSSTKSSGSESDRSERPVLV 2438
            ++ T   +      RS S S+   +   G+G + +    + SS  SS     RS  P   
Sbjct: 1794 SQSTSRRRQ-----RSRSRSRVTRRRRGGSGYHSRSPARQESSRTSSRRRRGRSRTPPTS 1848

Query: 2439 RQSTFIKEAPSPTLRRKLEESASFESLSPSSRPASPTRSQAQTPVLSPSLPDMSLSTHSS 2498
            R+ +  + +P+P  R +   S           PA+  RS+++TP++S      S S  S 
Sbjct: 1849 RKRSRSRTSPAPWKRSRSRAS-----------PATHRRSRSRTPLISRR---RSRSRTSP 1894

Query: 2499 VQAGGWRKLPPNLSPTIEYNDGR--PAKRHDIARSHSESPSRLPINRSGTWKREHSKHSS 2556
            V     R+     S T   +  R  P  R    RS S +P   P+ R  +  R  +    
Sbjct: 1895 VSR---RRSRSRTSVTRRRSRSRASPVSRR---RSRSRTP---PVTRRRSRSRTPTTRRR 1945

Query: 2557 SLPRVS--TWRRTGSSSSILSASSESSEKAKSEDEKHVNSISGTKQSKENQVSAKGTWRK 2614
            S  R    T RR+ S +  ++     S  +     +  +  S   + +    ++  T R+
Sbjct: 1946 SRSRTPPVTRRRSRSRTPPVTRRRSRSRTSPITRRRSRSRTSPVTRRRSRSRTSPVTRRR 2005

Query: 2615 IKENEFSPTNSTSQTVSSGA-TNGAESKTLIYQMAPAVSKTEDVWVRIEDCPINNPRSGR 2673
             +      T   S++ +  A    + S+T +     + S++     R           G+
Sbjct: 2006 SRSRTSPVTRRRSRSRTPPAIRRRSRSRTPLLPRKRSRSRSPLAIRRRSRSRTPRTARGK 2065

Query: 2674 SPTGNTPPVI--DSVSEKANPNIKDSKDNQAKQNVGNGSVPMRTVGLENRLNSFIQVDAP 2731
                 +PP I   S S  ++   + +     + + G+ + P+      +R++ F     P
Sbjct: 2066 RSLTRSPPAIRRRSASGSSSDRSRSATPPATRNHSGSRTPPVAL--NSSRMSCF---SRP 2120

Query: 2732 DQKGTEI----KPGQNNPVPVSETNESSIVE-----------RTPFSSSSSSKHSSPSGT 2776
                T +     PG   P+  S T  S + +           R P    +S   +     
Sbjct: 2121 SMSPTPLDRCRSPGMLEPLGSSRTPMSVLQQAGGSMMDGPGPRIPDHQRTSVPENHAQSR 2180

Query: 2777 VAARVTPFNYNPS--PRKSSADSTSARPSQIPTPV 2809
            +A  +T  +   +  P   SA   +AR SQ+P PV
Sbjct: 2181 IALALTAISLGTARPPPSMSAAGLAARMSQVPAPV 2215



 Score = 85.1 bits (209), Expect = 9e-16
 Identities = 209/977 (21%), Positives = 350/977 (35%), Gaps = 113/977 (11%)

Query: 1878 KAELRKAKENKESEAKVTSHTELTSNQQSANKTQAIAKQPINRGQPKPILQKQSTFPQSS 1937
            K   +K K   ESE+K   H   T   +  +K +   +       PK     +ST   S+
Sbjct: 210  KKSSKKKKHRSESESKKRKHRSPTPKSKRKSKDKKRKRSRSTTPAPKSRRAHRSTSADSA 269

Query: 1938 KDIPDRGAATDEKLQNFAIENTPVCFSHNSSLSSLSDIDQENNNKENE-PIKETEPPDSQ 1996
                   + T       A   T     H ++L+  S         E + P  E     +Q
Sbjct: 270  SS-----SDTSRSRSRSAAAKT-----HTTALAGRSPSPASGRRGEGDAPFSEPGTTSTQ 319

Query: 1997 GEPSKPQASGYAPKSFHVEDTPVCFSRNSSLSSLSIDSEDDLLQECISSAMPKKKKPSRL 2056
              PS P+ +   P S + +       ++++  S S +          SS  P+   P+ L
Sbjct: 320  -RPSSPETATKQPSSPYEDKDKDKKEKSATRPSPSPER---------SSTGPEPPAPTPL 369

Query: 2057 KGDNEKHSPRNMGGILGEDLTLDLKDIQRPDSEHGLSPDSENFDWKAIQEGANSIVS-SL 2115
              +    SP+ +        T   ++   P SE   SP  +    K+ ++   S  S S 
Sbjct: 370  LAERHGGSPQPLA------TTPLSQEPVNPPSE--ASPTRDRSPPKSPEKLPQSSSSESS 421

Query: 2116 HQAAAAACLSRQASSDSDSILSLKSGISLGSPFHLTPDQEEKPFTSNKGPRILKPGEKST 2175
              +     +SR ASS  +S    K   + GS   ++     K  +  +  R        +
Sbjct: 422  PPSPQPTKVSRHASSSPESP---KPAPAPGSHREISSSPTSKNRSHGRAKRDKSHSHTPS 478

Query: 2176 LETKKIESESKGIKGGKKVYKSLITGKVRSNS---------EISGQMKQPLQANM----- 2221
                +  S +   +G  +       G  RS S         +  G+ + P +        
Sbjct: 479  RRMGRSRSPATAKRGRSRSRTPTKRGHSRSRSPQWRRSRSAQRWGRSRSPQRRGRSRSPQ 538

Query: 2222 -PSISRGRTMIHIPGVRNS----SSSTSPVSKKGPPLKTPASKSPSEGQT-ATTSPRGAK 2275
             P  SR R        R++    S S SP ++     +TPA +  S  +T A    R   
Sbjct: 539  RPGWSRSRNTQRRGRSRSARRGRSHSRSPATRGRSRSRTPARRGRSRSRTPARRRSRSRT 598

Query: 2276 PSVKSELS--PVARQTSQIGGSSKAPSRSGSRDSTPSRPAQQPLSRPIQSPGRNSISPGR 2333
            P+ +   S  P  R  S+    S+ P+R  SR  +P R   +  S   +S    S +P R
Sbjct: 599  PTRRRSRSRTPARRGRSR----SRTPARRRSRTRSPVRRRSRSRSPARRSGRSRSRTPAR 654

Query: 2334 NGISPPNKLSQLPRTSSPSTASTKSSGSGKMSYTSPGRQMSQQNLTKQTGLSKNASSIPR 2393
             G S     S+ P     S + T +  SG+    +P R+   ++ T + G S++ S + R
Sbjct: 655  RGRSR----SRTPARRGRSRSRTPARRSGRSRSRTPARRGRSRSRTPRRGRSRSRSLVRR 710

Query: 2394 SESASKGLNQMNNGNGANKKVELSRMSSTKSSGSESDRSERPVLVRQSTFIKEAPSPTLR 2453
              S S+   +      ++++   SR S  +S  + S   ++  +  + +    +P    +
Sbjct: 711  GRSHSRTPQRRGRSGSSSERKNKSRTSQRRSRSNSSPEMKKSRISSRRSRSLSSPRSKAK 770

Query: 2454 RKLEESASFESLSP-----SSRPASPTRSQAQTPVLSPSLPDMSLSTHSSVQAGGWRKLP 2508
             +L    S    SP     S  P   +RS +  P      P     + SS       K P
Sbjct: 771  SRLSLRRSLSGSSPCPKQKSQTPPRRSRSGSSQPKAKSRTPPRRSRSSSSPPPKQKSKTP 830

Query: 2509 -----PNLSPTIEYNDGRPAKRHDIARSHSESPSRLPINRS-----------GTWKREHS 2552
                  + SP  +   G P ++  I    +   S  P  RS                 HS
Sbjct: 831  SRQSHSSSSPHPKVKSGTPPRQGSITSPQANEQSVTPQRRSCFESSPDPELKSRTPSRHS 890

Query: 2553 KHSSSLPRVSTWRRTGSSSSILSASSESSEKAKSEDEKHVNSISGTKQSKENQVSAKGTW 2612
               SS PRV +      S    S SS    K K+       S SG+     ++V+++ T 
Sbjct: 891  CSGSSPPRVKSSTPPRQSP---SRSSSPQPKVKAIISPRQRSHSGSSSPSPSRVTSRTTP 947

Query: 2613 RKIKENEFSPTNSTSQTVSSGATNGAESKTLIYQMAPAVSKTEDVWVRIEDCPINNPRSG 2672
            R+            S++VS    +  ES+ L+ + + + S + D  V+ E  P  +    
Sbjct: 948  RR------------SRSVS--PCSNVESR-LLPRYSHSGSSSPDTKVKPETPPRQSHSGS 992

Query: 2673 RSP----TGNTPPVIDSVSEKANPNIKDSKDNQAKQNVGNGSVPMRTVGLENRLNSFIQV 2728
             SP       TPP       K+    + SKD+  +   G+ S+            S+  V
Sbjct: 993  ISPYPKVKAQTPPGPSLSGSKSPCPQEKSKDSLVQSCPGSLSLCAGVKSSTPPGESYFGV 1052

Query: 2729 DAPDQKGTEIKPGQNNPVPVSETNESSIVERTPFSSSSSSK-HSSPSGTVAARVTPFN-- 2785
             +   KG      Q +P   S+T+   + +    S S  SK  +SP G  +   +P    
Sbjct: 1053 SSLQLKG----QSQTSPDHRSDTSSPEVRQSHSESPSLQSKSQTSPKGGRSRSSSPVTEL 1108

Query: 2786 YNPSPRKSSADSTSARP 2802
             + SP +      SA P
Sbjct: 1109 ASRSPIRQDRGEFSASP 1125



 Score = 83.2 bits (204), Expect = 3e-15
 Identities = 377/1715 (21%), Positives = 612/1715 (35%), Gaps = 288/1715 (16%)

Query: 1189 SSQKQSFSFSKSSSGQSSKTEHMSSSSENTSTPSSNA-----------------KRQNQL 1231
            +SQ++S S   +SS +  K+   S  S + S+P S A                 K+++Q 
Sbjct: 736  TSQRRSRS---NSSPEMKKSRISSRRSRSLSSPRSKAKSRLSLRRSLSGSSPCPKQKSQT 792

Query: 1232 HPSSAQSRSGQPQ-KAATCKVSSINQETIQTYCVEDTPICFSRCSSLSSLSSAEDEIGC- 1289
             P  ++S S QP+ K+ T    S +  +        TP   SR S  SS    + + G  
Sbjct: 793  PPRRSRSGSSQPKAKSRTPPRRSRSSSSPPPKQKSKTP---SRQSHSSSSPHPKVKSGTP 849

Query: 1290 -NQTTQEADSANTLQIAEIKEKIGTRSAEDPVSEVPAVSQH-------PRTKSSRLQGSS 1341
              Q +  +  AN   +   + +    S+ DP  +    S+H       PR KSS     S
Sbjct: 850  PRQGSITSPQANEQSVTP-QRRSCFESSPDPELKSRTPSRHSCSGSSPPRVKSSTPPRQS 908

Query: 1342 LSSESARHKAVEFSSGAKSPSKSGAQTPKSPPEHYVQETPLMFSRCTSVSSLDSFESRSI 1401
             S  S+    V+     +  S SG+ +P SP     + TP    R  SVS   + ESR +
Sbjct: 909  PSRSSSPQPKVKAIISPRQRSHSGSSSP-SPSRVTSRTTP---RRSRSVSPCSNVESRLL 964

Query: 1402 ---ASSVQSEPCSGMV---------SGIISPSDLPDSPGQTMP-PSRSKTPPPPPQTAQT 1448
               + S  S P + +          SG ISP   P    QT P PS S +  P PQ    
Sbjct: 965  PRYSHSGSSSPDTKVKPETPPRQSHSGSISP--YPKVKAQTPPGPSLSGSKSPCPQEKSK 1022

Query: 1449 K---REVPKNKAPTAEKRESGPKQAAVNAAVQRVQVLPDADTLL-HFATESTPDGFSCSS 1504
                +  P + +  A  + S P   +    V  +Q+   + T   H +  S+P+     S
Sbjct: 1023 DSLVQSCPGSLSLCAGVKSSTPPGESY-FGVSSLQLKGQSQTSPDHRSDTSSPEVRQSHS 1081

Query: 1505 SLSALSLDEPFIQKDVELRIMPPVQE--------NDNGNETESE------QPKESNENQE 1550
               +L        K    R   PV E         D G  + S        P++S    +
Sbjct: 1082 ESPSLQSKSQTSPKGGRSRSSSPVTELASRSPIRQDRGEFSASPMLKSGMSPEQSRFQSD 1141

Query: 1551 KEAEKTIDSEKDLLDDSDDDDIEILEECIISAMPTKSSRKAKKPAQTASKLPPPVARKPS 1610
              +  T+DS   LL  S  +  E  E+    A+P +    A  P Q     P PV  +P 
Sbjct: 1142 SSSYPTVDS-NSLLGQSRLETAESKEK---MALPPQEDATASPPRQKDKFSPFPVQDRPE 1197

Query: 1611 QLPVYKLLPSQNRLQPQKHVSFTPGDDMPRVYCVEGTPINFSTATSLSDLTIESPPNELA 1670
               V+K      R  P++    +     P     E    N +  TS  D  +     +  
Sbjct: 1198 SSLVFK---DTLRTPPRER---SGAGSSP-----ETKEQNSALPTSSQDEELMEVVEKSE 1246

Query: 1671 AGEGVRGGAQSGEFEKRDTIPTEGRSTDEAQGGKTSSVTIPELDDNKAEEGDILAECINS 1730
               G      S E ++  T   E  S+ E +     S+T   LD ++++      E  + 
Sbjct: 1247 EPAGQILSHLSSELKEMSTSNFE--SSPEVEERPAVSLT---LDQSQSQASLEAVEVPSM 1301

Query: 1731 AMPKGKSHKPFRVKKIMDQVQQASASSSAPNKNQLDGKKKKPTSPVKPIPQNTEYRTRVR 1790
            A   G  H     K++         S+S   +N      +   S       NT + + V+
Sbjct: 1302 ASSWGGPHFSPEHKEL---------SNSPLRENSFGSPLEFRNSGPLGTEMNTGFSSEVK 1352

Query: 1791 K--NADSKNNLNAERVFSDNKDSKKQNLKNNSKVFNDKLPNNEDRVRGSFAFDSPHHYTP 1848
            +  N    N L  +     + D K+Q+ +++    ++  P+  ++               
Sbjct: 1353 EDLNGPFLNQLETD----PSLDMKEQSTRSSGHSSSELSPDAVEKAG------------- 1395

Query: 1849 IEGTPYCFSRNDSLSSLDFDDDDVDLSREKAELRKAKENKESEAKVTSHTELTSNQQSAN 1908
                    S N S+SS   D      SRE++    + E K+   +  S            
Sbjct: 1396 -------MSSNQSISSPVLDAVPRTPSRERSSSASSPEMKDGLPRTPS-----------R 1437

Query: 1909 KTQAIAKQPINRGQPKPILQKQSTFPQSSKDI---PDRG-AATDEKLQNFAIENTPVCFS 1964
            ++++ +   +  G   P     S      KDI   P RG +  D   +  A+  TP   S
Sbjct: 1438 RSRSGSSPGLRDGSGTPSRHSLSGSSPGMKDIPRTPSRGRSECDSSPEPKALPQTPRPRS 1497

Query: 1965 HNSSLSSLSDIDQENNNKENEPIKETEPPDSQGEPSKPQASGYAPKSFHVEDTPVCFSRN 2024
             + S         E NNK   P +E     S  E S  Q +        V  TP+   R+
Sbjct: 1498 RSPS-------SPELNNKCLTPQRER----SGSESSVDQKT--------VARTPL-GQRS 1537

Query: 2025 SSLSSLSIDSEDDLLQECISSAMPKKKKPSRLKGDN--EKHSPRNMGGILGEDLTLDLKD 2082
             S SS  +D +         SA P+++  S    D+  +  +P       G    +D K 
Sbjct: 1538 RSGSSQELDVK--------PSASPQERSESDSSPDSKAKTRTPLRQRSRSGSSPEVDSKS 1589

Query: 2083 IQRP-DSEHGLSPDSENFDWKAIQEGANSIVSSLHQAAAAACLSRQASSDSDSILSLKSG 2141
               P  S  G SP+ ++    A +  + S  S   +A A   L R++ S S S       
Sbjct: 1590 RLSPRRSRSGSSPEVKDKPRAAPRAQSGSDSSPEPKAPAPRALPRRSRSGSSS-KGRGPS 1648

Query: 2142 ISLGSPFHLTPDQEEKPFTSNKGPRIL-KPGEKSTLETKKIESESKGIKGGKKVYKSLIT 2200
                S    +P+   K  T+ +G R   +P  KS    ++  S S             +T
Sbjct: 1649 PEGSSSTESSPEHPPKSRTARRGSRSSPEPKTKSRTPPRRRSSRS----------SPELT 1698

Query: 2201 GKVRSNSEISGQMKQPLQANMPSISRGRTMIHIPGVRNSSSSTSPVSKKGPPLKTPAS-- 2258
             K R +       ++   A+    +R RT    P  R S S +SP     P  K+ +S  
Sbjct: 1699 RKARLS-------RRSRSASSSPETRSRTP---PRHRRSPSVSSP----EPAEKSRSSRR 1744

Query: 2259 -KSPSEGQTATTSPRGAKPSVKSELSPVARQTS--QIGGSSKAPSRSGSRDSTP-----S 2310
             +S S  +T TTS RG  PS K      +R  S  +   +++   RSGS  ST      S
Sbjct: 1745 RRSASSPRTKTTSRRGRSPSPKPRGLQRSRSRSRREKTRTTRRRDRSGSSQSTSRRRQRS 1804

Query: 2311 RPAQQPLSRPIQSPGRNSISPGRNGISPPNKLSQLPRTSSPSTASTKSSGSGKMSYTSPG 2370
            R   +   R     G +S SP R   S  +   +  R+ +P T+  +S      S TSP 
Sbjct: 1805 RSRSRVTRRRRGGSGYHSRSPARQESSRTSSRRRRGRSRTPPTSRKRS-----RSRTSPA 1859

Query: 2371 RQMSQQNLTKQTGLSKNASSIP-----RSESASKGLNQMNNGNGANKKVELSRMSSTKSS 2425
                 ++        ++ S  P     RS S +  +++  + +  +     SR  ++  S
Sbjct: 1860 PWKRSRSRASPATHRRSRSRTPLISRRRSRSRTSPVSRRRSRSRTSVTRRRSRSRASPVS 1919

Query: 2426 GSESDRSERPVLVRQSTFIKEAPSPTLRRKLEESASFESLSPSSRPASPTRSQAQTPVL- 2484
               S     PV  R+S     + +PT RR+        S +P   P +  RS+++TP + 
Sbjct: 1920 RRRSRSRTPPVTRRRS----RSRTPTTRRR------SRSRTP---PVTRRRSRSRTPPVT 1966

Query: 2485 -----SPSLPDMSLSTHSSVQAGGWRKLPPNLSPTIEYNDGRPAKRHDIARSHSESP--- 2536
                 S + P     + S       R+     SP                RS S +P   
Sbjct: 1967 RRRSRSRTSPITRRRSRSRTSPVTRRRSRSRTSPVTRRRSRSRTSPVTRRRSRSRTPPAI 2026

Query: 2537 SRLPINRSGTWKREHSKHSSSLPRVSTWRRTGSSSSILSASSESSEKAKSEDEKHVNSIS 2596
             R   +R+    R+ S+  S L      RR   S +  +A  + S   +S       S S
Sbjct: 2027 RRRSRSRTPLLPRKRSRSRSPL----AIRRRSRSRTPRTARGKRS-LTRSPPAIRRRSAS 2081

Query: 2597 GTKQSKENQVSAKGTWRKIKENEFSPTNSTSQTVSSGATNGAESKTLIYQMAPAVSKTED 2656
            G+   +    +   T R    +   P    S  +S  +        L    +P + +   
Sbjct: 2082 GSSSDRSRSATPPAT-RNHSGSRTPPVALNSSRMSCFSRPSMSPTPLDRCRSPGMLE--- 2137

Query: 2657 VWVRIEDCPINNPRSGRSPTGNTPPVIDSVSEKANPNIKDSKDNQAKQNVGNGSVPMRTV 2716
                    P+    S R+P         S+ +   P I D +     +N     + +   
Sbjct: 2138 --------PLG---SSRTPMSVLQQAGGSMMDGPGPRIPDHQRTSVPENHAQSRIALAL- 2185

Query: 2717 GLENRLNSFIQVDAPDQKGTEIKPGQNNPVP-VSETNESSIVERTPFSSSSSSKHSSPSG 2775
                               T I  G   P P +S    ++ + + P      S  ++P+ 
Sbjct: 2186 -------------------TAISLGTARPPPSMSAAGLAARMSQVPAPVPLMSLRTAPAA 2226

Query: 2776 TVAARVTPFNYNPSPRKSSADSTSARPSQIPTPVN 2810
             +A+R+      P+   ++ +  SAR   IPT VN
Sbjct: 2227 NLASRI------PAASAAAMNLASARTPAIPTAVN 2255



 Score = 66.2 bits (160), Expect = 4e-10
 Identities = 106/436 (24%), Positives = 174/436 (39%), Gaps = 50/436 (11%)

Query: 2209 ISGQMKQPLQANMPSISR---GRTMIHIPGVRNSSSSTSPVSKKGPPLKTPASKSPSEGQ 2265
            ++G    P  AN PS SR        ++ G R S+ +T+PV+  G   +T A+ +P+   
Sbjct: 2311 LTGSGTPPTAANYPSSSRTPQAPASANLVGPR-SAHATAPVNIAGS--RTAAALAPASLT 2367

Query: 2266 TATTSPRGAKPSVKSELSPVARQTSQIGGSSKAPSRSGSRDSTP----------SRPAQQ 2315
            +A  +P  +  ++ S   P++    ++ G +  P    +R  TP          S  A  
Sbjct: 2368 SARMAPALSGANLTSPRVPLSAY-ERVSGRTSPPLLDRARSRTPPSAPSQSRMTSERAPS 2426

Query: 2316 PLSRPIQSPGRNSISPGRNGI-SP-PNKLSQLPRT--------------SSPSTASTKSS 2359
            P SR  Q+P ++ + P ++   SP P+  S   R               SS + A+T SS
Sbjct: 2427 PSSRMGQAPSQSLLPPAQDQPRSPVPSAFSDQSRCLIAQTTPVAGSQSLSSGAVATTTSS 2486

Query: 2360 G---SGKMSYTSPGRQMSQQNLTKQTGLSKNASSI----PRSESASKGLNQMNNGNGANK 2412
                +G +S  +PG   S       +  ++  S++    P  E  S   +  ++ + ++ 
Sbjct: 2487 AGDHNGMLSVPAPGVPHSDVGEPPASTGAQQPSALAALQPAKERRSSSSSSSSSSSSSSS 2546

Query: 2413 KVELSRMSSTKSSGSESDRSERPVLVRQSTFIKEAPSPTLRRKLEESASFESLSPSSRPA 2472
                S  SS+ SS S+S+ S  PV  +    +K  PSPT   K    A  E   P   PA
Sbjct: 2547 SSSSSSSSSSGSSSSDSEGSSLPV--QPEVALKRVPSPTPAPK---EAVREGRPPEPTPA 2601

Query: 2473 SPTRSQAQTPVLSPSLPDMSLSTHSSVQAGGWRKLPPNLSPTIEYNDGRPAKRHDIARSH 2532
               R  + +   S S    S S+ SS  +        + S +   +   PAK    A   
Sbjct: 2602 KRKRRSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSPSPAKPGPQALPK 2661

Query: 2533 SESPSRLP----INRSGTWKREHSKHSSSLPRVSTWRRTGS-SSSILSASSESSEKAKSE 2587
              SP + P     +RS     +  + S SL      RR  S   S     S SSE+    
Sbjct: 2662 PASPKKPPPGERRSRSPRKPIDSLRDSRSLSYSPVERRRPSPQPSPRDQQSSSSERGSRR 2721

Query: 2588 DEKHVNSISGTKQSKE 2603
             ++  +     K+ +E
Sbjct: 2722 GQRGDSRSPSHKRRRE 2737



 Score = 65.9 bits (159), Expect = 6e-10
 Identities = 154/749 (20%), Positives = 262/749 (34%), Gaps = 102/749 (13%)

Query: 2151 TPDQEEKPFTSNKGPRILKPGEKSTLETKKIESESKGIKGGKKVYKSLITGKVRSNSEIS 2210
            TP Q++K    ++G R      +S+   ++ +  SK     KK ++S    K R +   +
Sbjct: 184  TPKQKKKKKKKDRGRR-----SESSSPRRERKKSSK-----KKKHRSESESKKRKHRSPT 233

Query: 2211 GQMKQPLQANMPSISRGRTMIHIPGVRNSSSSTSPVSKKGPPLKTPASKSPSEGQTATTS 2270
             + K+  ++      R R+    P  R +  STS  S          S+S +  +T TT+
Sbjct: 234  PKSKR--KSKDKKRKRSRSTTPAPKSRRAHRSTSADSASSSDTSRSRSRSAA-AKTHTTA 290

Query: 2271 PRGAKPSVKSELSPVARQTSQIGGSSKAPSRSGSRDSTPSRPAQQPLS------------ 2318
              G  PS  S      R+       S+  + S  R S+P    +QP S            
Sbjct: 291  LAGRSPSPAS-----GRRGEGDAPFSEPGTTSTQRPSSPETATKQPSSPYEDKDKDKKEK 345

Query: 2319 ---RPIQSPGRNSISPGRNGISP---------PNKLSQLPRTSSPSTASTKSSGSGKMSY 2366
               RP  SP R+S  P     +P         P  L+  P +  P    +++S +   S 
Sbjct: 346  SATRPSPSPERSSTGPEPPAPTPLLAERHGGSPQPLATTPLSQEPVNPPSEASPTRDRSP 405

Query: 2367 TSPGRQMSQQNLTKQTGLSKNASSIPRSESASKGLNQMNNGNGANKKVELSRMSSTKSSG 2426
                 ++ Q + ++ +  S   + + R  S+S    +     G+++++  S  S  +S G
Sbjct: 406  PKSPEKLPQSSSSESSPPSPQPTKVSRHASSSPESPKPAPAPGSHREISSSPTSKNRSHG 465

Query: 2427 -SESDRSERPVLVRQSTFIKEAPSPTLRRKLEESASFESLSPSSRPASPTRSQAQTPVLS 2485
             ++ D+S               PS  + R    + +    S S  P     S++++P   
Sbjct: 466  RAKRDKSH-----------SHTPSRRMGRSRSPATAKRGRSRSRTPTKRGHSRSRSPQWR 514

Query: 2486 PSLPDMSLSTHSSVQAGGWRKLPPNLSPTIEYNDGRPAKRHDI--ARSHSESP------- 2536
             S          S Q  G  + P     +   N  R  +       RSHS SP       
Sbjct: 515  RSRSAQRWGRSRSPQRRGRSRSPQRPGWSRSRNTQRRGRSRSARRGRSHSRSPATRGRSR 574

Query: 2537 SRLPINRSGTWKREHSKHSSSLPRVSTWRRTGSSSSILSASSESSEKAKSEDEKHVNSIS 2596
            SR P  R  +  R  ++  S   R  T RR+ S +      S S   A+          S
Sbjct: 575  SRTPARRGRSRSRTPARRRSR-SRTPTRRRSRSRTPARRGRSRSRTPARRRSRTR----S 629

Query: 2597 GTKQSKENQVSAKGTWRKIKENEFSPTNSTSQTVSSGATNGAESKTLIYQMAPAVSKTED 2656
              ++   ++  A+ + R           S S+T +    +   S+T   +   + S+T  
Sbjct: 630  PVRRRSRSRSPARRSGRSRSRTPARRGRSRSRTPARRGRS--RSRTPARRSGRSRSRTP- 686

Query: 2657 VWVRIEDCPINNPRSGRSPTGNT---------PPVIDSVSEKANPNIKDSKDNQAKQNVG 2707
               R        PR GRS + +           P     S  ++     S+ +Q +    
Sbjct: 687  --ARRGRSRSRTPRRGRSRSRSLVRRGRSHSRTPQRRGRSGSSSERKNKSRTSQRRSR-S 743

Query: 2708 NGSVPMRTVGLENRLNSFIQVDAPDQK----------GTEIKPGQNNPVPV----SETNE 2753
            N S  M+   + +R +  +       K          G+   P Q +  P     S +++
Sbjct: 744  NSSPEMKKSRISSRRSRSLSSPRSKAKSRLSLRRSLSGSSPCPKQKSQTPPRRSRSGSSQ 803

Query: 2754 SSIVERTPFSSSSSSKHSSPSGTVAARVTPFNYNPSPRKSSADSTSARPSQIPTPVNNNT 2813
                 RTP   S SS    P           + + SP       T  R   I +P  N  
Sbjct: 804  PKAKSRTPPRRSRSSSSPPPKQKSKTPSRQSHSSSSPHPKVKSGTPPRQGSITSPQANEQ 863

Query: 2814 KKRDSKTDSTESS-----GTQSPKRHSGS 2837
                 +    ESS      +++P RHS S
Sbjct: 864  SVTPQRRSCFESSPDPELKSRTPSRHSCS 892



 Score = 60.8 bits (146), Expect = 2e-08
 Identities = 365/1994 (18%), Positives = 672/1994 (33%), Gaps = 337/1994 (16%)

Query: 1023 TPINYSLKYSDEQLNSGRQSPSQNERWARPKHIIEDEIKQSEQRQSRNQSTTYPVYTEST 1082
            TP   S   S +     R  P ++   + P      +  ++  RQS + S+ +P     T
Sbjct: 792  TPPRRSRSGSSQPKAKSRTPPRRSRSSSSPP---PKQKSKTPSRQSHSSSSPHPKVKSGT 848

Query: 1083 DDKHLKFQPHFGQQECVSPYRS------------------RGANGSETNRVGSNHGINQN 1124
              +          ++ V+P R                      +GS   RV S+    Q+
Sbjct: 849  PPRQGSITSPQANEQSVTPQRRSCFESSPDPELKSRTPSRHSCSGSSPPRVKSSTPPRQS 908

Query: 1125 VSQSLCQEDDYEDDKPTNYSERYSEEEQHEEEERPTNYSIKYNEEKRHVDQPIDYSLKYA 1184
             S+S          +P   +     +  H     P+   +      R        S+   
Sbjct: 909  PSRS-------SSPQPKVKAIISPRQRSHSGSSSPSPSRVTSRTTPRR-----SRSVSPC 956

Query: 1185 TDIPSSQKQSFSFSKSSSGQSS-KTEHMSSSSENTS-TPSSNAKRQNQLHPSSAQSRSGQ 1242
            +++ S     +S S SSS  +  K E     S + S +P    K Q    PS + S+S  
Sbjct: 957  SNVESRLLPRYSHSGSSSPDTKVKPETPPRQSHSGSISPYPKVKAQTPPGPSLSGSKSPC 1016

Query: 1243 PQKAATCKVSSINQETIQTYCVEDTPICFSRCSSL-SSLSSAEDEIGCNQTTQEADSANT 1301
            PQ            E  +   V+  P   S C+ + SS    E   G +    +  S  +
Sbjct: 1017 PQ------------EKSKDSLVQSCPGSLSLCAGVKSSTPPGESYFGVSSLQLKGQSQTS 1064

Query: 1302 LQIAEIKEKIGTRSAEDPVSEVPAVSQHPRT--KSSRLQGSSLSSESARHKAVEFSSGAK 1359
                + +    +       SE P++    +T  K  R + SS  +E A    +    G  
Sbjct: 1065 ---PDHRSDTSSPEVRQSHSESPSLQSKSQTSPKGGRSRSSSPVTELASRSPIRQDRGEF 1121

Query: 1360 SPS---KSGAQTPKSPPEHYVQETPLMFSRCTSVSSLDSFESRSIASSVQSEPCSGMVSG 1416
            S S   KSG     SP +   Q         +  SS  + +S S+    + E        
Sbjct: 1122 SASPMLKSGM----SPEQSRFQ---------SDSSSYPTVDSNSLLGQSRLETAESKEKM 1168

Query: 1417 IISPS-DLPDSPGQTMPPSRSKTPPPPPQTA--------QTKREVPKNKAPTAEKRESGP 1467
             + P  D   SP    P  + K  P P Q           T R  P+ ++      E+  
Sbjct: 1169 ALPPQEDATASP----PRQKDKFSPFPVQDRPESSLVFKDTLRTPPRERSGAGSSPETKE 1224

Query: 1468 KQAAVNAAVQRVQVL--------PDADTLLHFATE---STPDGFSCSSSLS-----ALSL 1511
            + +A+  + Q  +++        P    L H ++E    +   F  S  +      +L+L
Sbjct: 1225 QNSALPTSSQDEELMEVVEKSEEPAGQILSHLSSELKEMSTSNFESSPEVEERPAVSLTL 1284

Query: 1512 DEPFIQKDVELRIMPPVQENDNGNETESEQPKESNENQEKEA---------------EKT 1556
            D+   Q  +E   +P +  +  G     E  + SN    + +               E  
Sbjct: 1285 DQSQSQASLEAVEVPSMASSWGGPHFSPEHKELSNSPLRENSFGSPLEFRNSGPLGTEMN 1344

Query: 1557 IDSEKDLLDDSDDDDIEILEECIISAMPTKSSRKAKKPAQTASKLPPPVARKPSQL---- 1612
                 ++ +D +   +  LE      M  +S+R +     ++S+L P    K        
Sbjct: 1345 TGFSSEVKEDLNGPFLNQLETDPSLDMKEQSTRSS---GHSSSELSPDAVEKAGMSSNQS 1401

Query: 1613 ---PVYKLLP-SQNRLQPQKHVSFTPGDDMPRVYCVEGTPINFSTATSLSDLTIESPPNE 1668
               PV   +P + +R +     S    D +PR      TP   S + S       SP   
Sbjct: 1402 ISSPVLDAVPRTPSRERSSSASSPEMKDGLPR------TPSRRSRSGS-------SPGLR 1448

Query: 1669 LAAGEGVRGGAQSGEFEKRDT--IPTEGRSTDEAQGGKTSSVTIPELDDNKAEEGDILAE 1726
              +G   R          +D    P+ GRS  ++     +    P          ++  +
Sbjct: 1449 DGSGTPSRHSLSGSSPGMKDIPRTPSRGRSECDSSPEPKALPQTPRPRSRSPSSPELNNK 1508

Query: 1727 CINSAMPKGKSHKPFRVKKIM-DQVQQASASSSAPNKNQLDGKKKKPTSPVKPIPQNTEY 1785
            C+     +  S      K +    + Q S S S+   +       +  S     P +++ 
Sbjct: 1509 CLTPQRERSGSESSVDQKTVARTPLGQRSRSGSSQELDVKPSASPQERSESDSSP-DSKA 1567

Query: 1786 RTRVRKNADSKNNLNAERVFSDNKDSKKQNLKNNSKVFNDKLPNNEDRVRGSFAFDSPHH 1845
            +TR      S++  + E V S ++ S +++   +S    DK P    R + S +  SP  
Sbjct: 1568 KTRTPLRQRSRSGSSPE-VDSKSRLSPRRSRSGSSPEVKDK-PRAAPRAQ-SGSDSSPEP 1624

Query: 1846 YTPIEGTPYCFSRNDSLSSLDFDDDDVDLSREKAELRKAKENKESEAKVTSHTELTSNQQ 1905
              P    P    R                SR  +  +    + E  +   S  E     +
Sbjct: 1625 KAP---APRALPRR---------------SRSGSSSKGRGPSPEGSSSTESSPEHPPKSR 1666

Query: 1906 SANKTQAIAKQPINRGQPKPILQKQSTFPQSSKDIP----DRGAATDEKLQNFAIENTPV 1961
            +A +    + +P  + +  P  +   + P+ ++        R A++  + ++     TP 
Sbjct: 1667 TARRGSRSSPEPKTKSRTPPRRRSSRSSPELTRKARLSRRSRSASSSPETRS----RTPP 1722

Query: 1962 CFSHNSSLSSLSDIDQENNNKE----NEPIKETEPPDSQGEPSKPQASGYAPKSFHVEDT 2017
                + S+SS    ++  +++     + P  +T     +    KP+    +      E T
Sbjct: 1723 RHRRSPSVSSPEPAEKSRSSRRRRSASSPRTKTTSRRGRSPSPKPRGLQRSRSRSRREKT 1782

Query: 2018 PVCFSRNSSLSSLSIDSEDDLLQECISSAMPKKKKPSRLKGDNEKHSPRNMGGILGEDLT 2077
                 R+ S SS S                 ++++ SR +    + + R  GG       
Sbjct: 1783 RTTRRRDRSGSSQSTS---------------RRRQRSRSRS---RVTRRRRGG------- 1817

Query: 2078 LDLKDIQRPDSEHGLSPDSENFDWKAIQEGANSIVSSLHQAAAAACLSRQASSDSDSILS 2137
                        H  SP        A QE + +        +     SR+ S    S   
Sbjct: 1818 ---------SGYHSRSP--------ARQESSRTSSRRRRGRSRTPPTSRKRSRSRTSPAP 1860

Query: 2138 LKSGISLGSPFHLTPDQEEKPFTSNKGPR-----ILKPGEKSTLETKKIESESKGIKGGK 2192
             K   S  SP      +   P  S +  R     + +   +S     +  S S+     +
Sbjct: 1861 WKRSRSRASPATHRRSRSRTPLISRRRSRSRTSPVSRRRSRSRTSVTRRRSRSRASPVSR 1920

Query: 2193 KVYKSLITGKVRSNSEI-SGQMKQPLQANMPSISRGRTMIHIPGV--RNSSSSTSPVSKK 2249
            +  +S      R  S   +   ++  ++  P ++R R+    P V  R S S TSP++++
Sbjct: 1921 RRSRSRTPPVTRRRSRSRTPTTRRRSRSRTPPVTRRRSRSRTPPVTRRRSRSRTSPITRR 1980

Query: 2250 GPPLKT-PASKSPSEGQTATTSPRGAKPSVKSELSPVARQTSQIGGSSKAPS--RSGSRD 2306
                +T P ++  S  +T+  + R ++    S  SPV R+ S+    S+ P   R  SR 
Sbjct: 1981 RSRSRTSPVTRRRSRSRTSPVTRRRSR----SRTSPVTRRRSR----SRTPPAIRRRSRS 2032

Query: 2307 STPSRPAQQPLSR-------------PIQSPGRNSIS---PGRNGISPPNKLSQLPRTSS 2350
             TP  P ++  SR             P  + G+ S++   P     S     S   R+++
Sbjct: 2033 RTPLLPRKRSRSRSPLAIRRRSRSRTPRTARGKRSLTRSPPAIRRRSASGSSSDRSRSAT 2092

Query: 2351 PSTASTKSSG--------SGKMS-YTSPGRQMSQQNLTKQTGLSK--NASSIPRSESASK 2399
            P      S          S +MS ++ P    +  +  +  G+ +   +S  P S     
Sbjct: 2093 PPATRNHSGSRTPPVALNSSRMSCFSRPSMSPTPLDRCRSPGMLEPLGSSRTPMSVLQQA 2152

Query: 2400 GLNQMNNG--------------NGANKKVELSRMSSTKSSGSESDRSERPVLVRQSTFIK 2445
            G + M+                N A  ++ L+  + +  +           L  + + + 
Sbjct: 2153 GGSMMDGPGPRIPDHQRTSVPENHAQSRIALALTAISLGTARPPPSMSAAGLAARMSQVP 2212

Query: 2446 EAPSPTLRRKLEESASFESLSPSSRPASPTRSQAQTPVLSPSLPDMSLSTHSSVQAGGWR 2505
             AP P +  +   +A+  S  P++  A+   + A+TP +  ++      T ++  A    
Sbjct: 2213 -APVPLMSLRTAPAANLASRIPAASAAAMNLASARTPAIPTAVNLADSRTPAAAAAMNLA 2271

Query: 2506 KLPPNLSPT-IEYNDGRPAKRHDIARSHSESPSRLP---INRSGTWKREHSKHSSSLPRV 2561
                 ++P+ +   D R      +  + + +P+ L    +  SGT     +  SSS    
Sbjct: 2272 SPRTAVAPSAVNLADPRTPTAPAVNLAGARTPAALAALSLTGSGTPPTAANYPSSS---- 2327

Query: 2562 STWRRTGSSSSILSASSESSEKAKSEDEKHVNSISGTKQSKENQVSAKGTWRKIKENEFS 2621
             T +   S++ +   S+ ++        +   +++    +      A            S
Sbjct: 2328 RTPQAPASANLVGPRSAHATAPVNIAGSRTAAALAPASLTSARMAPA-----------LS 2376

Query: 2622 PTNSTSQTVSSGATNGAESKTLIYQMAPAVSKT-----EDVWVRIEDCPINNPRSGRSPT 2676
              N TS  V   A      +T    +  A S+T         +  E  P  + R G++P+
Sbjct: 2377 GANLTSPRVPLSAYERVSGRTSPPLLDRARSRTPPSAPSQSRMTSERAPSPSSRMGQAPS 2436

Query: 2677 GNT---------PPVIDSVSEKANPNIKDSKDNQAKQNVGNGSVPMRTVGLENRLNSFIQ 2727
             +           PV  + S+++   I  +      Q++ +G+V   T    +  N  + 
Sbjct: 2437 QSLLPPAQDQPRSPVPSAFSDQSRCLIAQTTPVAGSQSLSSGAVATTTSSAGDH-NGMLS 2495

Query: 2728 VDAPD------------------------QKGTEIKPGQNNPVPVSETNESSIVERTPFS 2763
            V AP                         Q   E +   ++    S ++ SS    +  S
Sbjct: 2496 VPAPGVPHSDVGEPPASTGAQQPSALAALQPAKERRSSSSSSSSSSSSSSSSSSSSSSSS 2555

Query: 2764 SSSSSKHSSPSGTVAARVTPFNYNPSPRKSSADSTSARPSQIPTPVNNNTKKRDSKTDST 2823
            S SSS  S  S             PSP  + A   + R  + P P     K+R S + S+
Sbjct: 2556 SGSSSSDSEGSSLPVQPEVALKRVPSP--TPAPKEAVREGRPPEPTPAKRKRRSSSSSSS 2613

Query: 2824 ESSGTQSPKRHSGS 2837
             SS + S    S S
Sbjct: 2614 SSSSSSSSSSSSSS 2627



 Score = 58.5 bits (140), Expect = 9e-08
 Identities = 144/715 (20%), Positives = 244/715 (34%), Gaps = 92/715 (12%)

Query: 2169 KPGEKSTLETKKIESESKGIKGGKKVYKSLITGKVRSNSEISGQMKQPLQANMPSISRGR 2228
            +P +  +L  +   S S   K  KK  K     +  S+S    + K   +    S S  +
Sbjct: 166  EPPKPYSLVRESSSSRSPTPKQKKKKKKKDRGRRSESSSPRRERKKSSKKKKHRSESESK 225

Query: 2229 TMIHIPGVRNSSSSTSPVSKKGPPLKTPASKSPSEGQTATTSPRGAKPSVKSELSPVARQ 2288
               H      S   +    +K     TPA KS    ++ +     +  + +S     A +
Sbjct: 226  KRKHRSPTPKSKRKSKDKKRKRSRSTTPAPKSRRAHRSTSADSASSSDTSRSRSRSAAAK 285

Query: 2289 --TSQIGGSSKAP----------------SRSGSRDSTPSRPAQQPLS------------ 2318
              T+ + G S +P                + S  R S+P    +QP S            
Sbjct: 286  THTTALAGRSPSPASGRRGEGDAPFSEPGTTSTQRPSSPETATKQPSSPYEDKDKDKKEK 345

Query: 2319 ---RPIQSPGRNSISPGRNGISP---------PNKLSQLPRTSSPSTASTKSSGSGKMSY 2366
               RP  SP R+S  P     +P         P  L+  P +  P    +++S +   S 
Sbjct: 346  SATRPSPSPERSSTGPEPPAPTPLLAERHGGSPQPLATTPLSQEPVNPPSEASPTRDRSP 405

Query: 2367 TSPGRQMSQQNLTKQTGLSKNASSIPRSESASKGLNQMNNGNGANKKVELSRMSSTKSSG 2426
                 ++ Q + ++ +  S   + + R  S+S    +     G+++++  S  S  +S G
Sbjct: 406  PKSPEKLPQSSSSESSPPSPQPTKVSRHASSSPESPKPAPAPGSHREISSSPTSKNRSHG 465

Query: 2427 -SESDRSERPVLVRQSTFIKEAPSPTLRRKLEESASFESLSPSSRPASPTRSQAQTPVLS 2485
             ++ D+S               PS  + R    + +    S S  P     S++++P   
Sbjct: 466  RAKRDKSH-----------SHTPSRRMGRSRSPATAKRGRSRSRTPTKRGHSRSRSPQWR 514

Query: 2486 PSLPDMSLSTHSSVQAGGWRKLPPNLSPTIEYNDGRPAKRHDI--ARSHSESP------- 2536
             S          S Q  G  + P     +   N  R  +       RSHS SP       
Sbjct: 515  RSRSAQRWGRSRSPQRRGRSRSPQRPGWSRSRNTQRRGRSRSARRGRSHSRSPATRGRSR 574

Query: 2537 SRLPINRSGTWKREHSKHSSSLPRVSTWRRTGSSSSILSASSESSEKAKSEDEKHVNSIS 2596
            SR P  R  +  R  ++  S   R  T RR+ S +      S S   A+    +   + S
Sbjct: 575  SRTPARRGRSRSRTPARRRSR-SRTPTRRRSRSRTPARRGRSRSRTPAR----RRSRTRS 629

Query: 2597 GTKQSKENQVSAKGTWRKIKENEFSPTNSTSQTVSSGATNGAESKTLIYQMAPAVSKTED 2656
              ++   ++  A+ + R           S S+T        + S+T   +   + S+T  
Sbjct: 630  PVRRRSRSRSPARRSGRSRSRTPARRGRSRSRT--PARRGRSRSRTPARRSGRSRSRTP- 686

Query: 2657 VWVRIEDCPINNPRSGRSPTGNTPPVIDSVSEKANPNIKDSKDNQAKQNVGNGSVPMRTV 2716
               R        PR GRS + +      S S       +    ++ K          RT 
Sbjct: 687  --ARRGRSRSRTPRRGRSRSRSLVRRGRSHSRTPQRRGRSGSSSERKNK-------SRTS 737

Query: 2717 GLENRLNSFIQVDAPDQKGTEIKPGQNNPVPVSETNESSIVERTPFSSSSSSKHSSPSGT 2776
               +R NS     +P+ K + I   ++  +    +   S +      S SS      S T
Sbjct: 738  QRRSRSNS-----SPEMKKSRISSRRSRSLSSPRSKAKSRLSLRRSLSGSSPCPKQKSQT 792

Query: 2777 VAARVTPFNYNPSPRKSSADSTSARPSQIPTPVNNNTKKRDSKTDSTESSGTQSP 2831
               R    +  P   KS      +R S  P P      K+ SKT S +S  + SP
Sbjct: 793  PPRRSRSGSSQPK-AKSRTPPRRSRSSSSPPP------KQKSKTPSRQSHSSSSP 840



 Score = 58.5 bits (140), Expect = 9e-08
 Identities = 329/1633 (20%), Positives = 558/1633 (34%), Gaps = 230/1633 (14%)

Query: 1331 RTKSSRLQGSSLSSESAR--HKAVEFSSGAKSP------SKSGAQTPKSPPEHYVQETPL 1382
            R KSS+ +     SES +  H++    S  KS       S+S    PKS   H       
Sbjct: 209  RKKSSKKKKHRSESESKKRKHRSPTPKSKRKSKDKKRKRSRSTTPAPKSRRAHRSTSADS 268

Query: 1383 MFSRCTSVSSLDSFESRSIASSVQSEPCSGM----VSGIISPSDLPDS-PG--QTMPPSR 1435
              S  TS S      SRS A+   +   +G      SG     D P S PG   T  PS 
Sbjct: 269  ASSSDTSRS-----RSRSAAAKTHTTALAGRSPSPASGRRGEGDAPFSEPGTTSTQRPSS 323

Query: 1436 SKTPPPPPQTAQTKREVPKNK------APTAEKRESGPKQAAVNAAVQRVQVLPDADTLL 1489
             +T    P +    ++  K +      +P+ E+  +GP+              P    LL
Sbjct: 324  PETATKQPSSPYEDKDKDKKEKSATRPSPSPERSSTGPEP-------------PAPTPLL 370

Query: 1490 HFATESTPDGFSCSSSLSALSLDEPFIQKDVELRIMPPVQENDNGNETESEQPKESNENQ 1549
                  +P   + +          P  Q+ V     PP + +   + +  + P++  ++ 
Sbjct: 371  AERHGGSPQPLATT----------PLSQEPVN----PPSEASPTRDRSPPKSPEKLPQSS 416

Query: 1550 EKEAEKTIDSEKDLLDDSDDDDIEILEECIISAMPTKSSRKAKKPAQTASKLPPPVA-RK 1608
              E+                           S  PTK SR A    ++    P P + R+
Sbjct: 417  SSESSPP------------------------SPQPTKVSRHASSSPESPKPAPAPGSHRE 452

Query: 1609 PSQLPVYKLLPSQNRLQPQKHVSFTPGDDMPRVYCVEGTPINFS---TATSLSDLTIESP 1665
             S  P  K   S  R +  K  S TP   M R           S   T T        SP
Sbjct: 453  ISSSPTSKNR-SHGRAKRDKSHSHTPSRRMGRSRSPATAKRGRSRSRTPTKRGHSRSRSP 511

Query: 1666 PNELAAGEGVRGGAQSGEFEKRDTIPTE---GRSTDEAQGGKTSSVTIPELDDNKAEEGD 1722
                +      G ++S +   R   P      RS +  + G++ S               
Sbjct: 512  QWRRSRSAQRWGRSRSPQRRGRSRSPQRPGWSRSRNTQRRGRSRSARRGRSHSRSPATRG 571

Query: 1723 ILAECINSAMPKGKSHKPFRVKKIMDQVQQASASSSAP-----NKNQLDGKKKKPTSPVK 1777
                   +   + +S  P R +       +  + S  P     ++++   +++  T    
Sbjct: 572  RSRSRTPARRGRSRSRTPARRRSRSRTPTRRRSRSRTPARRGRSRSRTPARRRSRTR--S 629

Query: 1778 PIPQNTEYRTRVRKNADSKNNLNAERVFSDNKDSKKQNLKNNSKVFNDKLPNNEDRVRGS 1837
            P+ + +  R+  R++  S++   A R  S ++   +   +  S+       +   R R  
Sbjct: 630  PVRRRSRSRSPARRSGRSRSRTPARRGRSRSRTPAR---RGRSRSRTPARRSGRSRSRTP 686

Query: 1838 FAFDSPHHYTPIEG----------------TPYCFSRNDSLSSLDFDDDDVDLSREKAEL 1881
                     TP  G                TP    R+ S S           ++ +   
Sbjct: 687  ARRGRSRSRTPRRGRSRSRSLVRRGRSHSRTPQRRGRSGSSSERK--------NKSRTSQ 738

Query: 1882 RKAKENKESEAKVTSHTELTSNQQSANKTQAIAKQPINRGQPKPILQKQSTFPQSSKDIP 1941
            R+++ N   E K +  +   S   S+ +++A ++  + R      L   S  P+     P
Sbjct: 739  RRSRSNSSPEMKKSRISSRRSRSLSSPRSKAKSRLSLRRS-----LSGSSPCPKQKSQTP 793

Query: 1942 DRGAATDEKLQNFAIENTPVCFSHNSSL-----SSLSDIDQENNNKENEPIKETEPPDSQ 1996
             R + +    Q  A   TP   S +SS       S +   Q +++    P  ++  P  Q
Sbjct: 794  PRRSRSGSS-QPKAKSRTPPRRSRSSSSPPPKQKSKTPSRQSHSSSSPHPKVKSGTPPRQ 852

Query: 1997 GEPSKPQASGYAP-----KSFHVEDTPVCFSRNSSLSSLSIDSEDDLLQECISSAMPKKK 2051
            G  + PQA+  +        F     P   SR  S  S S  S        + S+ P ++
Sbjct: 853  GSITSPQANEQSVTPQRRSCFESSPDPELKSRTPSRHSCSGSSPPR-----VKSSTPPRQ 907

Query: 2052 KPSRLKGDNEKH----SPRNMGGILGEDLTLDLKDIQR--PDSEHGLSPDSENFDWKAIQ 2105
             PSR      K     SPR      G       +   R  P     +SP S N + + + 
Sbjct: 908  SPSRSSSPQPKVKAIISPRQRSHS-GSSSPSPSRVTSRTTPRRSRSVSPCS-NVESRLLP 965

Query: 2106 EGANSIVSSLHQAAAAACLSRQASSDSDSIL-----SLKSGISLGSPFHLTPDQEEKP-- 2158
              ++S  SS           RQ+ S S S           G SL       P ++ K   
Sbjct: 966  RYSHSGSSSPDTKVKPETPPRQSHSGSISPYPKVKAQTPPGPSLSGSKSPCPQEKSKDSL 1025

Query: 2159 FTSNKGPRILKPGEKSTLETKKIESESKGIKGGKKVYKSLITGKVRSNSEISGQMKQPLQ 2218
              S  G   L  G KS+  T   ES   G+   +   +S  +   RS++  S +++Q   
Sbjct: 1026 VQSCPGSLSLCAGVKSS--TPPGESYF-GVSSLQLKGQSQTSPDHRSDTS-SPEVRQS-H 1080

Query: 2219 ANMPSISRGRTMIHIPGVRNSSSSTSPVSKKGPPLKTPASKSPSEGQTATTSPRGAKPSV 2278
            +  PS+          G   SSS  + ++ + P  +     S S    +  SP  ++   
Sbjct: 1081 SESPSLQSKSQTSPKGGRSRSSSPVTELASRSPIRQDRGEFSASPMLKSGMSPEQSRFQS 1140

Query: 2279 KSELSPVARQTSQIGGSSKAPSRSGSR-------DSTPSRPAQQPLSRP--IQSPGRNSI 2329
             S   P     S +G S    + S  +       D+T S P Q+    P  +Q    +S+
Sbjct: 1141 DSSSYPTVDSNSLLGQSRLETAESKEKMALPPQEDATASPPRQKDKFSPFPVQDRPESSL 1200

Query: 2330 SPGRNGISPPNKLS---QLPRTSSPSTASTKSSGSGKM------SYTSPGRQMSQQNLTK 2380
                   +PP + S     P T   ++A   SS   ++      S    G+ +S  +   
Sbjct: 1201 VFKDTLRTPPRERSGAGSSPETKEQNSALPTSSQDEELMEVVEKSEEPAGQILSHLSSEL 1260

Query: 2381 QTGLSKNASSIPRSE---SASKGLNQMNNGNGANKKVELSRMSSTKS----SGSESDRSE 2433
            +   + N  S P  E   + S  L+Q +    + + VE+  M+S+      S    + S 
Sbjct: 1261 KEMSTSNFESSPEVEERPAVSLTLDQ-SQSQASLEAVEVPSMASSWGGPHFSPEHKELSN 1319

Query: 2434 RPVLVRQSTF---IKEAPSPTLRRKLEESASFESLSPSSRPASPTRSQAQTPVLSPSLPD 2490
             P+  R+++F   ++   S  L  ++    S E     +    P  +Q +T    PSL  
Sbjct: 1320 SPL--RENSFGSPLEFRNSGPLGTEMNTGFSSEVKEDLN---GPFLNQLET---DPSLDM 1371

Query: 2491 MSLSTHSS-----------VQAGGWRKLPPNLSPTIEYNDGRPAKRHDIARSHSESPSRL 2539
               ST SS           V+  G        SP ++     P++    + S  E    L
Sbjct: 1372 KEQSTRSSGHSSSELSPDAVEKAGMSSNQSISSPVLDAVPRTPSRERSSSASSPEMKDGL 1431

Query: 2540 PINRSGTWKREHSKHSSSLPRVSTWRRTGSSSSILSASSESSEKAKSEDEKHVNSISGTK 2599
            P   S          S S P +     T S  S LS SS   +       +  +    + 
Sbjct: 1432 PRTPS------RRSRSGSSPGLRDGSGTPSRHS-LSGSSPGMKDIPRTPSRGRSECDSSP 1484

Query: 2600 QSKENQVSAKGTWRKIKENEFSPTNSTSQTVSSGATNGAESKTLIYQMAPAVSKT---ED 2656
            + K    + +   R     E +    T Q   SG+ +  + KT+        S++   ++
Sbjct: 1485 EPKALPQTPRPRSRSPSSPELNNKCLTPQRERSGSESSVDQKTVARTPLGQRSRSGSSQE 1544

Query: 2657 VWVRIEDCPINNPRSGRSPTGNTP---PVIDSVSEKANPNIKDSKDNQAKQNVGNGSVPM 2713
            + V+    P     S  SP        P+       ++P + DSK   + +   +GS P 
Sbjct: 1545 LDVKPSASPQERSESDSSPDSKAKTRTPLRQRSRSGSSPEV-DSKSRLSPRRSRSGSSPE 1603

Query: 2714 RTVGLENRLNSFIQVDAPDQKGTEIKPGQNNPVPVSETNESSIVERTPFSSSSSSKHSSP 2773
                ++++  +  +  +      E K      +P    + SS   R P    SSS  SSP
Sbjct: 1604 ----VKDKPRAAPRAQSGSDSSPEPKAPAPRALPRRSRSGSSSKGRGPSPEGSSSTESSP 1659

Query: 2774 SGTVAARVT--PFNYNPSPRKSSADSTSARPSQIPTPVNNNTK--KRDSKTDSTESSGTQ 2829
                 +R        +P P+  S      R S+    +    +  +R     S+  + ++
Sbjct: 1660 EHPPKSRTARRGSRSSPEPKTKSRTPPRRRSSRSSPELTRKARLSRRSRSASSSPETRSR 1719

Query: 2830 SPKRHSGSYLVTS 2842
            +P RH  S  V+S
Sbjct: 1720 TPPRHRRSPSVSS 1732



 Score = 54.7 bits (130), Expect = 1e-06
 Identities = 73/280 (26%), Positives = 111/280 (39%), Gaps = 43/280 (15%)

Query: 1214 SSENTSTPSSN---AKRQNQLHPSSAQSRSGQPQKAATCKVSSINQETIQTYCVEDTPIC 1270
            +SE   +PSS    A  Q+ L P+  Q RS  P         S   +  +    + TP+ 
Sbjct: 2420 TSERAPSPSSRMGQAPSQSLLPPAQDQPRSPVP---------SAFSDQSRCLIAQTTPVA 2470

Query: 1271 FSRCSSLSSLSSAEDEIGCNQTTQEADSANTLQIAEIKEKIGTRSAEDPVSEVPAV--SQ 1328
             S+  S  ++++     G +     +  A  +  +++ E   +  A+ P S + A+  ++
Sbjct: 2471 GSQSLSSGAVATTTSSAG-DHNGMLSVPAPGVPHSDVGEPPASTGAQQP-SALAALQPAK 2528

Query: 1329 HPRTKSSRLQGSSLSSESARHKAVEFSSGAKSPSKSGAQTPKSP-------------PEH 1375
              R+ SS    SS SS S+   +   SSG+ S    G+  P  P             P+ 
Sbjct: 2529 ERRSSSSSSSSSSSSSSSSSSSSSSSSSGSSSSDSEGSSLPVQPEVALKRVPSPTPAPKE 2588

Query: 1376 YVQE------TPLMFSRCTSVSSLDSFESRSIASSVQSEPCSGMVSGIISPSDLPDSPGQ 1429
             V+E      TP    R +S SS  S  S S +SS  S   S   S   S S    S   
Sbjct: 2589 AVREGRPPEPTPAKRKRRSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS--- 2645

Query: 1430 TMPPSRSKTPPPPPQTAQTKREVPKNKAPTAEKRESGPKQ 1469
                S S +P  P   A  K   PK K P  E+R   P++
Sbjct: 2646 ----SSSPSPAKPGPQALPKPASPK-KPPPGERRSRSPRK 2680



 Score = 53.5 bits (127), Expect = 3e-06
 Identities = 113/557 (20%), Positives = 187/557 (33%), Gaps = 81/557 (14%)

Query: 2290 SQIGGSSKAPSRSGSRDSTPSRPAQQPLSRPIQSPGRNSISPGRNGISPPNKLSQLPRTS 2349
            S + GSS  P R       P+    +P S   +S    S +P +          +   +S
Sbjct: 144  SYVDGSSFDPQRRAREAKQPAPEPPKPYSLVRESSSSRSPTPKQKKKKKKKDRGRRSESS 203

Query: 2350 SPSTASTKS---------SGSGKMSYTSPGRQMSQQNLTKQTGLSKNASSIPRSESASKG 2400
            SP     KS         S S K  + SP  +  +++  K+   S++ +  P+S  A + 
Sbjct: 204  SPRRERKKSSKKKKHRSESESKKRKHRSPTPKSKRKSKDKKRKRSRSTTPAPKSRRAHRS 263

Query: 2401 LNQMNNGNGANKKVELSRMSSTKSSGSESDRSERPVLVRQSTFIK-EAPSPTLRRKLEES 2459
                            +   S  SS +   RS        +T +   +PSP   R+ E  
Sbjct: 264  ----------------TSADSASSSDTSRSRSRSAAAKTHTTALAGRSPSPASGRRGEGD 307

Query: 2460 ASFESLSPSS--RPASPTRSQAQTPVLSPSLPDMSLSTHSSVQAGGWRKLPPNLSPTIEY 2517
            A F     +S  RP+SP     +T    PS P          ++       P  S T   
Sbjct: 308  APFSEPGTTSTQRPSSP-----ETATKQPSSPYEDKDKDKKEKSATRPSPSPERSST--- 359

Query: 2518 NDGRPAKRHDIARSHSESPSRLPINRSGTWKREHSKHSSSLPRVSTWRRTGSSSSILSAS 2577
                PA    +A  H  SP   P+  +   +   +  S + P  +  R    S   L  S
Sbjct: 360  GPEPPAPTPLLAERHGGSPQ--PLATTPLSQEPVNPPSEASP--TRDRSPPKSPEKLPQS 415

Query: 2578 SESSEKAKSEDEKHVNSISGTKQSKENQVSAKGTWRKIKENEFSPTNSTSQTVSSGATNG 2637
            S S     S     V+  + +         A G+ R+I  +  S   S  +     + + 
Sbjct: 416  SSSESSPPSPQPTKVSRHASSSPESPKPAPAPGSHREISSSPTSKNRSHGRAKRDKSHSH 475

Query: 2638 AESKTLIYQMAPAVSKTEDVWVRIEDCPINNPRSGRSPTGNTPPVIDSVSEKANPNIKDS 2697
              S+ +    +PA +K                   R  + +  P     S   +P  + S
Sbjct: 476  TPSRRMGRSRSPATAK-------------------RGRSRSRTPTKRGHSRSRSPQWRRS 516

Query: 2698 KDNQAKQNVGNGSVPMRTVGLENRLNSFIQVDAPDQKGTEIKPGQNNPVPVSETNESSIV 2757
            +   + Q  G    P R                  +  +  +PG +          S   
Sbjct: 517  R---SAQRWGRSRSPQRR----------------GRSRSPQRPGWSRSRNTQRRGRSRSA 557

Query: 2758 ER-TPFSSSSSSKHSSPSGTVAARVTPFNYNPSPRKSSADSTSARPSQIPTPVNNNTKKR 2816
             R    S S +++  S S T A R    +  P+ R+S + + + R S+  TP      + 
Sbjct: 558  RRGRSHSRSPATRGRSRSRTPARRGRSRSRTPARRRSRSRTPTRRRSRSRTPARRGRSR- 616

Query: 2817 DSKTDSTESSGTQSPKR 2833
             S+T +   S T+SP R
Sbjct: 617  -SRTPARRRSRTRSPVR 632



 Score = 48.5 bits (114), Expect = 9e-05
 Identities = 78/379 (20%), Positives = 136/379 (35%), Gaps = 42/379 (11%)

Query: 2025 SSLSSLSIDSEDDLLQECISSAMPKKKKPSRLKGDNEKHSPRNMGGILGEDLTLDLKDIQ 2084
            S+   +S  +   LL    S   P     SR+  +        MG    + L    +D  
Sbjct: 2388 SAYERVSGRTSPPLLDRARSRTPPSAPSQSRMTSERAPSPSSRMGQAPSQSLLPPAQDQP 2447

Query: 2085 RPDSEHGLSPDSENFDWKAIQEGANSIVSSLHQAAAAACLSRQASSDSDSILSLKS-GI- 2142
            R       S  S     + +      +  S   ++ A   +  ++ D + +LS+ + G+ 
Sbjct: 2448 RSPVPSAFSDQS-----RCLIAQTTPVAGSQSLSSGAVATTTSSAGDHNGMLSVPAPGVP 2502

Query: 2143 --SLGSPFHLTPDQEEKPFTSNKGPRILKPGEKSTLETKKIESESKGIKGGKKVYKSLIT 2200
               +G P   T  Q+     +      L+P ++    +    S S           S  +
Sbjct: 2503 HSDVGEPPASTGAQQPSALAA------LQPAKERRSSSSSSSSSSSSSSSSSSSSSSSSS 2556

Query: 2201 GKVRSNSEISGQMKQPLQANMPSISRGRTMIHIPGVRNSSSSTSPVSKKGPPLKTPASKS 2260
            G   S+SE S     P+Q   P ++  R     P  + +      V +  PP  TPA + 
Sbjct: 2557 GSSSSDSEGSSL---PVQ---PEVALKRVPSPTPAPKEA------VREGRPPEPTPAKRK 2604

Query: 2261 PSEGQTATTSPRGAKPSVKSELSPVARQTSQIGGSSKAPSRSGSRDSTPSRPAQQPLSRP 2320
                 ++++S   +  S  S  S  +  +S    SS + S S S   +P++P  Q L +P
Sbjct: 2605 RRSSSSSSSSSSSSSSSSSSSSS--SSSSSSSSSSSSSSSSSSSSSPSPAKPGPQALPKP 2662

Query: 2321 IQSPGRNSISPGRNGISPPNKLSQLPRTSSPSTASTKSSGSGKMSYTSPGRQMS---QQN 2377
              SP +           P  + S+ PR    S   ++S     +    P  Q S   QQ+
Sbjct: 2663 -ASPKKP---------PPGERRSRSPRKPIDSLRDSRSLSYSPVERRRPSPQPSPRDQQS 2712

Query: 2378 LTKQTGLSKNASSIPRSES 2396
             + + G  +      RS S
Sbjct: 2713 SSSERGSRRGQRGDSRSPS 2731



 Score = 43.9 bits (102), Expect = 0.002
 Identities = 48/197 (24%), Positives = 79/197 (40%), Gaps = 20/197 (10%)

Query: 1188 PSSQKQSFSFSKSSSGQSSKTEHMSSSSENTSTPSSNAKRQN-QLHPSSAQSRSGQPQKA 1246
            P+ +++S S S SSS  SS +   SSSS ++ + SS+++  +  + P  A  R   P  A
Sbjct: 2526 PAKERRSSSSSSSSSSSSSSSSSSSSSSSSSGSSSSDSEGSSLPVQPEVALKRVPSPTPA 2585

Query: 1247 ATCKVSSINQETIQTYCVEDTPICFSRCSSLSSLSSAEDEIGCNQTTQEADSANTLQIAE 1306
                     +   +    E TP    R SS SS SS+      + ++  + S+++   + 
Sbjct: 2586 P-------KEAVREGRPPEPTPAKRKRRSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2638

Query: 1307 IKEKIGTRSAEDPVSEVPAVSQHP-----------RTKSSRLQGSSL-SSESARHKAVEF 1354
                  + S+  P    P     P           R++S R    SL  S S  +  VE 
Sbjct: 2639 SSSSSSSSSSPSPAKPGPQALPKPASPKKPPPGERRSRSPRKPIDSLRDSRSLSYSPVER 2698

Query: 1355 SSGAKSPSKSGAQTPKS 1371
               +  PS    Q+  S
Sbjct: 2699 RRPSPQPSPRDQQSSSS 2715



 Score = 43.5 bits (101), Expect = 0.003
 Identities = 57/244 (23%), Positives = 88/244 (36%), Gaps = 24/244 (9%)

Query: 1319 PVSEVPAVSQHPRTKSSRLQGSSLSSESARHKAVEFSSGAKSPSKSGAQTPKSPPEHYVQ 1378
            PV+   ++S      ++   G      S     V  S   + P+ +GAQ P +       
Sbjct: 2468 PVAGSQSLSSGAVATTTSSAGDHNGMLSVPAPGVPHSDVGEPPASTGAQQPSA----LAA 2523

Query: 1379 ETPLMFSRCTSVSSLDSFESRSIASSVQSEPCSGMVSGIISPSDLPDSPGQTMPPSRSKT 1438
              P    R +S SS  S  S S +SS  S   SG  S     S LP  P   +   R  +
Sbjct: 2524 LQPAKERRSSSSSSSSSSSSSSSSSSSSSSSSSGSSSSDSEGSSLPVQPEVAL--KRVPS 2581

Query: 1439 PPPPPQTAQTKREVPKNKAPTAEKRESGPKQAAVNAAVQRVQVLPDADTLLHFATESTPD 1498
            P P P+ A  +   P    P   KR S    ++ +++         + +    ++ S+  
Sbjct: 2582 PTPAPKEA-VREGRPPEPTPAKRKRRSSSSSSSSSSS-------SSSSSSSSSSSSSSSS 2633

Query: 1499 GFSCSSSLSALSLDEPFIQKDVELRIMPPVQENDNGNETESEQPKESNENQEKEAEKTID 1558
              S SSS S+ S   P   K     +  P           S +     E + +   K ID
Sbjct: 2634 SSSSSSSSSSSSSSSPSPAKPGPQALPKPA----------SPKKPPPGERRSRSPRKPID 2683

Query: 1559 SEKD 1562
            S +D
Sbjct: 2684 SLRD 2687



 Score = 43.1 bits (100), Expect = 0.004
 Identities = 72/340 (21%), Positives = 119/340 (35%), Gaps = 54/340 (15%)

Query: 2522 PAKRHDIARSHSESPSRLPINRSGTWKREHSKHSSSLPRVSTWRRTGSSSSILSASSESS 2581
            P K + + R  S S S  P  +    K++  + S S                   SS   
Sbjct: 167  PPKPYSLVRESSSSRSPTPKQKKKKKKKDRGRRSES-------------------SSPRR 207

Query: 2582 EKAKSEDEKHVNSISGTKQSKENQVSAKGTWRKIKENEFSPTNSTSQTV-------SSGA 2634
            E+ KS  +K   S S +K+ K    + K   RK K+ +   + ST+          S+ A
Sbjct: 208  ERKKSSKKKKHRSESESKKRKHRSPTPKSK-RKSKDKKRKRSRSTTPAPKSRRAHRSTSA 266

Query: 2635 TNGAESKTLIYQMAPAVSKTEDVWVRIEDCPINNPRSGRSPTGNTP---PVIDSVSEKAN 2691
             + + S T   +   A +KT    +        +P SGR   G+ P   P   S    ++
Sbjct: 267  DSASSSDTSRSRSRSAAAKTHTTALAGRS---PSPASGRRGEGDAPFSEPGTTSTQRPSS 323

Query: 2692 PNIK--------DSKDNQAKQNVGNGSVPMRTVGLENRLNSFIQVDAP-----DQKGTEI 2738
            P           + KD   K+       P        R ++  +  AP     ++ G   
Sbjct: 324  PETATKQPSSPYEDKDKDKKEKSATRPSPS-----PERSSTGPEPPAPTPLLAERHGGSP 378

Query: 2739 KPGQNNPVPVSETNESSIVERTPFSSSSSSKHSSPSGTVAARVTPFNYNPSPRKSSADST 2798
            +P    P+     N  S    T   S   S    P  + +    P   +P P K S  ++
Sbjct: 379  QPLATTPLSQEPVNPPSEASPTRDRSPPKSPEKLPQSSSSESSPP---SPQPTKVSRHAS 435

Query: 2799 SARPSQIPTPVNNNTKKRDSKTDSTESSGTQSPKRHSGSY 2838
            S+  S  P P   + ++  S   S   S  ++ +  S S+
Sbjct: 436  SSPESPKPAPAPGSHREISSSPTSKNRSHGRAKRDKSHSH 475



 Score = 40.4 bits (93), Expect = 0.025
 Identities = 61/261 (23%), Positives = 92/261 (35%), Gaps = 24/261 (9%)

Query: 2082 DIQRPDSEHGLSPDSENFDWKAIQEGANSIVSSLHQAAAAACLSRQASSDSDSILSLKSG 2141
            D+  P +  G    S      A+Q       SS   +++++  S  +SS S S     S 
Sbjct: 2505 DVGEPPASTGAQQPSA---LAALQPAKERRSSSSSSSSSSSSSSSSSSSSSSSSSGSSSS 2561

Query: 2142 ISLGSPFHLTPDQEEKPFTS-----NKGPRILKPGEKSTLETKKIESESKGIKGGKKVYK 2196
             S GS   + P+   K   S      +  R  +P E +  + K+  S S           
Sbjct: 2562 DSEGSSLPVQPEVALKRVPSPTPAPKEAVREGRPPEPTPAKRKRRSSSSSSSSSSSSSSS 2621

Query: 2197 SLITGKVRSNSEISGQMKQPLQANMPSISRGRTMIHIPGVRNSSSSTSPVSKKGPPLKTP 2256
            S  +    S+S  S        ++  S S        P      +   P S K PP    
Sbjct: 2622 SSSSSSSSSSSSSSSSSSSSSSSSSSSPS--------PAKPGPQALPKPASPKKPPPGER 2673

Query: 2257 ASKSPSEGQTATTSPRGA--KPSVKSELSPVARQTSQIGGSSKAPSRSG----SRDSTPS 2310
             S+SP +   +    R     P  +   SP      Q   SS+  SR G    SR  +  
Sbjct: 2674 RSRSPRKPIDSLRDSRSLSYSPVERRRPSPQPSPRDQQSSSSERGSRRGQRGDSRSPSHK 2733

Query: 2311 RPAQQPLSRPIQSPGRNSISP 2331
            R  + P  RP++   R+S SP
Sbjct: 2734 RRRETPSPRPMRH--RSSRSP 2752



 Score = 32.7 bits (73), Expect = 5.2
 Identities = 22/71 (30%), Positives = 32/71 (45%)

Query: 1175 QPIDYSLKYATDIPSSQKQSFSFSKSSSGQSSKTEHMSSSSENTSTPSSNAKRQNQLHPS 1234
            +P     K  +   SS   S S S SSS  SS +   SSSS ++S+ SS++         
Sbjct: 2597 EPTPAKRKRRSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSPSPAKPGP 2656

Query: 1235 SAQSRSGQPQK 1245
             A  +   P+K
Sbjct: 2657 QALPKPASPKK 2667


>gi|91982772 mucin 17 [Homo sapiens]
          Length = 4493

 Score = 90.1 bits (222), Expect = 3e-17
 Identities = 337/1722 (19%), Positives = 610/1722 (35%), Gaps = 214/1722 (12%)

Query: 1185 TDIPSSQKQSFSFSKSSSGQSSKTEHMSSSSENTSTP--SSNAKRQNQLHPSSAQSRSGQ 1242
            T I S    +   + S +   S T   S++   TST   SS+   +    P+S  +    
Sbjct: 629  TTITSMSVSTTLVASSEASTLSTTPVDSNTPVTTSTEATSSSTTAEGTSMPTSTYTEGST 688

Query: 1243 PQKAA---TCKVSSINQETIQTYCVE-DTPICFSRCSSLSSLSSAEDEIGCNQTTQEADS 1298
            P  +    T  V+S    T+ T  V+  TP+  S  +S SS ++A+       T+  ++ 
Sbjct: 689  PLTSMPVNTTLVASSEASTLSTTPVDTSTPVTTSTEAS-SSPTTADG--ASMPTSTPSEG 745

Query: 1299 ANTLQIAEIKEKIGTRSAEDPVSEVPAVSQHPRTKSSRLQGSSLSSESARHKAVEFSSGA 1358
            +  L    + + + T S    +S  P  +    T S+    S  ++E         S G+
Sbjct: 746  STPLTSMPVSKTLLTSSEASTLSTTPLDTSTHITTSTEASCSPTTTEGTSMPISTPSEGS 805

Query: 1359 KSPSKSGAQ-TPKSPPEHYVQETPLMFSRC-----TSVSSLDS-FESRSIASSVQSEPCS 1411
               +      TP + PE     T  + S       T VSS  +  E  S+ +S  SE  +
Sbjct: 806  PLLTSIPVSITPVTSPEASTLSTTPVDSNSPVTTSTEVSSSPTPAEGTSMPTSTYSEGRT 865

Query: 1412 GMVSGIISPSDLPDSPGQTMPPSRSKTPPPPPQTAQTKREVPKNKAPTAEKRESGPKQAA 1471
             + S  +S + +  S   T+  +   T  P   + + +       +PT  +  S P    
Sbjct: 866  PLTSMPVSTTLVATSAISTLSTTPVDTSTPVTNSTEAR------SSPTTSEGTSMPTSTP 919

Query: 1472 VNAAVQRVQVLPDADTLLHFATESTPDGFSCSSSLSALSLDEPF-IQKDVELRIMPPVQE 1530
               +      +PD+         +TP   S + +LSA  +D    +    E    P   E
Sbjct: 920  GEGSTPLTS-MPDS---------TTPVVSSEARTLSATPVDTSTPVTTSTEATSSPTTAE 969

Query: 1531 NDNGNETESEQPKESNE---NQEKEAEKTIDSEKDLLDDSDDDDIEILEECIISAMPTKS 1587
               G    +  P E      +         +SE   L  +  D    L     ++ P  +
Sbjct: 970  ---GTSIPTSTPSEGTTPLTSTPVSHTLVANSEASTLSTTPVDSNTPLTTSTEASSPPPT 1026

Query: 1588 SRKAKKPAQTASKLPPPVARKP--------------SQLPVYKLLPSQNRLQPQKHVSFT 1633
            +     P  T S+   P+ R P              S  P     P     Q     +  
Sbjct: 1027 AEGTSMPTSTPSEGSTPLTRMPVSTTMVASSETSTLSTTPADTSTPVTTYSQASSSSTTA 1086

Query: 1634 PGDDMPRVYCVEGT------PINFSTATSLSDLTIESPPNELAAGEGVRGGAQSGEFEKR 1687
             G  MP     EG+      P++     S    T+ + P + +                 
Sbjct: 1087 DGTSMPTSTYSEGSTPLTSVPVSTRLVVSSEASTLSTTPVDTSIPV-------------- 1132

Query: 1688 DTIPTEGRSTDEAQGGKTSSVTIPELDDNKAEEGDILAECINSAMPKGKSHKPFRVKKIM 1747
             T  TE  S+     G +   + P           +    + S+     S  P   K   
Sbjct: 1133 -TTSTEASSSPTTAEGTSIPTSPPSEGTTPLASMPVSTTLVVSSEANTLSTTPVDSKT-- 1189

Query: 1748 DQVQQASASSSAPNKNQLD-------GKKKKPTS--PVKPIP-QNTEYRTRVRKNADSKN 1797
             QV  ++ +SS P   ++        G++  P +  PV+  P  ++E  T      D+  
Sbjct: 1190 -QVATSTEASSPPPTAEVTSMPTSTPGERSTPLTSMPVRHTPVASSEASTLSTSPVDTST 1248

Query: 1798 NLNAERVFSDNKDSKKQNLKNNSKVFNDKLPNNEDRVRGSFAFDSPHHYTPIEGTPYCFS 1857
             +      S +  + +             LP +     GS    S     P+  T     
Sbjct: 1249 PVTTSAETSSSPTTAE----------GTSLPTSTTS-EGSTLLTS----IPVSTTLVTSP 1293

Query: 1858 RNDSLSSLDFD-------DDDVDLSREKAELRKAKENKESEAKVTSHTELTSNQQ--SAN 1908
               +L +   D        ++V  S   AE      +  SE + T  T +  N    +++
Sbjct: 1294 EASTLLTTPVDTKGPVVTSNEVSSSPTPAEGTSMPTSTYSEGR-TPLTSIPVNTTLVASS 1352

Query: 1909 KTQAIAKQPINRGQPKPILQKQSTFPQSSKDIPDRGAATDE---KLQNFAIENTPVCFSH 1965
                ++  P++   P     +  + P +S+      +   E    L +  +  TPV  S 
Sbjct: 1353 AISILSTTPVDNSTPVTTSTEACSSPTTSEGTSMPNSNPSEGTTPLTSIPVSTTPVVSSE 1412

Query: 1966 NSSLSSLSDIDQENNNKENEPIKETEPPDSQGEPSKPQASGYAP-KSFHVEDTPVCFSRN 2024
             S+LS+             E        +    P+   + G  P KS  V +TPV  S  
Sbjct: 1413 ASTLSATPVDTSTPGTTSAEATSSPTTAEGISIPTSTPSEGKTPLKSIPVSNTPVANSEA 1472

Query: 2025 SSLSSLSIDSEDDLLQECISSAMPKKKKPSRLKGDNEKHSPRNMGGILGEDLTLDLKDIQ 2084
            S+LS+  +DS   ++     S+ P   + + +           +  I     T+      
Sbjct: 1473 STLSTTPVDSNSPVVTSTAVSSSPTPAEGTSIAISTPSEGSTALTSIPVSTTTV------ 1526

Query: 2085 RPDSEHGLSPDSENFDWKAIQEGANSIVSSLHQAAAAACLSRQASSDSDSILSLKSGISL 2144
                                   A+S ++SL    A         S + S  +   G S+
Sbjct: 1527 -----------------------ASSEINSLSTTPAVTSTPVTTYSQASSSPTTADGTSM 1563

Query: 2145 GSPFHLTPDQEEKPFTSNK-GPRILKPGEKSTLETKKIESESKGIKGGKKVYKSLITGKV 2203
             +    T  +   P TS      ++   E +TL T  I+S+++     +    S  T + 
Sbjct: 1564 QTS---TYSEGSTPLTSLPVSTMLVVSSEANTLSTTPIDSKTQVTASTEA--SSSTTAEG 1618

Query: 2204 RSNSEISGQMKQPLQANMPSISRGRTMIHIPGVRNSSSSTSPVSKKGPPL-KTPASKSPS 2262
             S +  +     PL  ++P  +   T +  P    S+ ST+PV    P +  T  S SP+
Sbjct: 1619 SSMTISTPSEGSPLLTSIPVST---TPVASPEA--STLSTTPVDSNSPVITSTEVSSSPT 1673

Query: 2263 EGQTATTSPRGAKPSVKSELSPVARQTSQIGGSSKAP-SRSGSRDSTPSRPAQQPLSRPI 2321
              +  T+ P       ++ L+ +  +T+ +  S+ +  S +   +STP   + +  S P 
Sbjct: 1674 PAE-GTSMPTSTYTEGRTPLTSITVRTTPVASSAISTLSTTPVDNSTPVTTSTEARSSPT 1732

Query: 2322 QSPGRNSISPGRNGISPPNKLSQLPRTSSPSTASTKSSGSGKMSYTSPGRQMSQQNLTKQ 2381
             S G +   P          L+ +P +++P  +S  S+ S     TS     S +  +  
Sbjct: 1733 TSEGTSM--PNSTPSEGTTPLTSIPVSTTPVLSSEASTLSATPIDTSTPVTTSTEATSSP 1790

Query: 2382 TGLSKNASSIPRSESASKGLNQMNNGNGANKKVELSRMSSTKSSGSESDRSERPVLVRQS 2441
            T  +   +SIP S + S+G+  + +   ++  V  S  S+  ++  +S+    PV+   S
Sbjct: 1791 T--TAEGTSIPTS-TLSEGMTPLTSTPVSHTLVANSEASTLSTTPVDSNS---PVVT--S 1842

Query: 2442 TFIKEAPSPTLRRKLEESASFE-SLSPSSRPASPTR---SQAQTPVLSPSLPDMSLSTHS 2497
            T +  +P+P     +  S   E S + +S P S T    S+  T   +P++    ++T++
Sbjct: 1843 TAVSSSPTPAEGTSIATSTPSEGSTALTSIPVSTTTVASSETNTLSTTPAVTSTPVTTYA 1902

Query: 2498 SVQAGGWRKLPPNLSPTIEYNDGRPAKRHDIARSHSESPSRLPINRSGTWKREHSKHSSS 2557
             V +        ++ PT    +GRP              + +P++ +     E +  S++
Sbjct: 1903 QVSSSPTTADGSSM-PTSTPREGRPPL------------TSIPVSTTTVASSEINTLSTT 1949

Query: 2558 LPRVSTWRRTGSSSSILSASSESSEKAKSEDEKHVNSISGTKQSKENQVSAKGTWRKIKE 2617
            L    T   T S +S    +++ +        +    ++    S    VS++ +      
Sbjct: 1950 LADTRTPVTTYSQASSSPTTADGTSMPTPAYSEGSTPLTSMPLSTTLVVSSEAS------ 2003

Query: 2618 NEFSPTNSTSQTVSSGATNGAESKTLIYQMAPAVSKTEDVWVRIEDCPINNPR--SGRSP 2675
               S T   + T ++ +T G+ S T     +   S   +    +   P++     S    
Sbjct: 2004 -TLSTTPVDTSTPATTSTEGSSSPTTAGGTSIQTSTPSERTTPLAGMPVSTTLVVSSEGN 2062

Query: 2676 TGNTPPVIDSVSEKANPNIKDSKDNQAKQNV-----GNGSVPMRTVGLENRLNSFIQVDA 2730
            T +T PV DS ++  N     S       ++       GS  + ++ L     S   V +
Sbjct: 2063 TLSTTPV-DSKTQVTNSTEASSSATAEGSSMTISAPSEGSPLLTSIPL-----STTPVAS 2116

Query: 2731 PDQKGTEIKPGQNNPVPVSETNESSIVERTPFSSSSSSKHSSPSGTVAARVTPFNYNPSP 2790
            P+       P  +N   ++ T  SS    +P  +  +S  +S        +T    + + 
Sbjct: 2117 PEASTLSTTPVDSNSPVITSTEVSS----SPIPTEGTSMQTSTYSDRRTPLTSMPVSTTV 2172

Query: 2791 RKSSADST-SARPSQIPTPVNNNTKKRDSKTDSTESSGTQSP 2831
              SSA ST S  P    TPV N+T+ R S    T S GT  P
Sbjct: 2173 VASSAISTLSTTPVDTSTPVTNSTEARSS---PTTSEGTSMP 2211



 Score = 85.5 bits (210), Expect = 7e-16
 Identities = 365/1792 (20%), Positives = 609/1792 (33%), Gaps = 282/1792 (15%)

Query: 1177 IDYSLKYATDIPSSQKQSFSFSKSSSGQSS-KTEHMSSSSENTSTPSSNAKRQNQLHPSS 1235
            I+ S+   T   SS + + + S+++S  +S  T    SS+E+TS+P++       +   S
Sbjct: 94   IESSVTSDTPGVSSTRMTPTESRTTSESTSDSTTLFPSSTEDTSSPTTPEGTDVPMSTPS 153

Query: 1236 AQSRSGQPQKAATCKVSSINQETIQTYCVE-DTPICFSRCSSLSSLSSAEDEIGCNQTTQ 1294
             +S S      +T  + S    T  TY V+  TP+  S  +S SS ++ E       T  
Sbjct: 154  EESISSTMAFVSTAPLPSFEAYTSLTYKVDMSTPLTTSTQAS-SSPTTPESTTIPKSTNS 212

Query: 1295 EADS------ANTLQIAEIKEKIGTRSAEDPVSEVPAVSQHPRTKSSRLQGSSLSSESAR 1348
            E  +      A+T+++A   E I   +    +S    +S    +  +  +G SLS+ +  
Sbjct: 213  EGSTPLTSMPASTMKVAS-SEAITLLTTPVEISTPVTISAQASSSPTTAEGPSLSNSAPS 271

Query: 1349 HKAVEFSSGAKSPS---KSGAQTPKSPPEHYVQETPLMFSRCTSVSSLDSFESRSIASSV 1405
              +   +    S      S A T  + P       P++ S   S SS  + E  SI +S 
Sbjct: 272  GGSTPLTRMPLSVMLVVSSEASTLSTTPA--ATNIPVITSTEAS-SSPTTAEGTSIPTST 328

Query: 1406 QSEPCSGMVSGIISPSDLPDSPGQTMPPSRSK-----TPPPPPQTAQTKREVPKNKAPTA 1460
             +E            + L  +P  TMP + S+       P    T  T    P +   TA
Sbjct: 329  YTE----------GSTPLTSTPASTMPVATSEMSTLSITPVDTSTLVTTSTEPSSLPTTA 378

Query: 1461 EKRESGPKQAAVNAAVQRVQVLPDADTLLHFATESTPDGFSCSSSLSALSLDE----PFI 1516
            E   +    + ++     +  +P +  L+  +  ST       S     +  E    P  
Sbjct: 379  E--ATSMLTSTLSEGSTPLTNMPVSTILVASSEASTTSTIPVDSKTFVTTASEASSSPTT 436

Query: 1517 QKDVELRIMPPVQENDNGNETESEQPKESNENQEKEAEK----TIDSEKDLLDDSDDDDI 1572
             +D  +    P      G+   +  P  +      EA       +DS+  +   ++    
Sbjct: 437  AEDTSIATSTP----SEGSTPLTSMPVSTTPVASSEASNLSTTPVDSKTQVTTSTEASSS 492

Query: 1573 EILEECIISAMPTKSSRKAKKPAQTASKLPPPVARKPSQLPVYKLLPSQNRLQPQKHVSF 1632
                E  +++MPT +  +   P  + S    PVA   +                   +S 
Sbjct: 493  PPTAE--VNSMPTSTPSEGSTPLTSMSVSTMPVASSEAST-----------------LST 533

Query: 1633 TPGDDMPRVYCVEGTPINFSTATSLSDLTIESPPNELAAGEGVRGGAQSGEFEKRDTIPT 1692
            TP D          TP+  S+  S S  T E      +          +     R  + +
Sbjct: 534  TPVD--------TSTPVTTSSEASSSSTTPEGTSIPTSTPSEGSTPLTNMPVSTRLVVSS 585

Query: 1693 EGRSTDEAQGGKTSSVTIPELDDNKAEEGDILAECINSAMPKGKSHKPFRVKKIMDQVQQ 1752
            E  +T        + VT      ++A      AE   ++MP                 ++
Sbjct: 586  EASTTSTTPADSNTFVT----TSSEASSSSTTAE--GTSMPTS------------TYSER 627

Query: 1753 ASASSSAPNKNQLDGKKKKPTSPVKPIPQNTEYRTRVRKNADSKNNLNAERVFSDNKDSK 1812
             +  +S      L    +  T    P+  NT   T     + S          +    S 
Sbjct: 628  GTTITSMSVSTTLVASSEASTLSTTPVDSNTPVTTSTEATSSST---------TAEGTSM 678

Query: 1813 KQNLKNNSKVFNDKLPNNEDRVRGSFAFDSPHHYTPIE-GTPYCFSRNDSLSSLDFDDDD 1871
              +           +P N   V  S A  S    TP++  TP   S   S S    D   
Sbjct: 679  PTSTYTEGSTPLTSMPVNTTLVASSEA--STLSTTPVDTSTPVTTSTEASSSPTTADGAS 736

Query: 1872 VDL---SREKAELRKAKENK----ESEAKVTSHTELTSNQQSANKTQAIAKQPINRGQPK 1924
            +     S     L     +K     SEA   S T L ++      T+A        G   
Sbjct: 737  MPTSTPSEGSTPLTSMPVSKTLLTSSEASTLSTTPLDTSTHITTSTEASCSPTTTEGTSM 796

Query: 1925 PILQKQSTFPQSSKDIPDRGAATDEKLQNFAIENTPVCFSHNSSLSSLSDIDQENNNKEN 1984
            PI              P  G+     L +  +  TPV     S+LS+             
Sbjct: 797  PI------------STPSEGSPL---LTSIPVSITPVTSPEASTLSTTPVDSNSPVTTST 841

Query: 1985 EPIKETEPPDSQGEPSKPQASGYAP-KSFHVEDTPVCFSRNSSLSSLSIDSEDDLLQECI 2043
            E      P +    P+   + G  P  S  V  T V  S  S+LS+  +D+   +     
Sbjct: 842  EVSSSPTPAEGTSMPTSTYSEGRTPLTSMPVSTTLVATSAISTLSTTPVDTSTPVTNSTE 901

Query: 2044 SSAMPKKKK----PSRLKGDNE---KHSPRNMGGILGED---LTLDLKDIQRP---DSEH 2090
            + + P   +    P+   G+        P +   ++  +   L+    D   P    +E 
Sbjct: 902  ARSSPTTSEGTSMPTSTPGEGSTPLTSMPDSTTPVVSSEARTLSATPVDTSTPVTTSTEA 961

Query: 2091 GLSP---DSENFDWKAIQEGANSIVSS--LHQAAAAACLSRQASSDSDSILSLKSGISLG 2145
              SP   +  +       EG   + S+   H   A +  S  +++  DS   L +     
Sbjct: 962  TSSPTTAEGTSIPTSTPSEGTTPLTSTPVSHTLVANSEASTLSTTPVDSNTPLTTSTEAS 1021

Query: 2146 SPFHL---------TPDQEEKPFTSNK-GPRILKPGEKSTLETKKIE-----------SE 2184
            SP            TP +   P T       ++   E STL T   +           S 
Sbjct: 1022 SPPPTAEGTSMPTSTPSEGSTPLTRMPVSTTMVASSETSTLSTTPADTSTPVTTYSQASS 1081

Query: 2185 SKGIKGGKKVYKSLITGKVRSNSEISGQMKQPLQANMPSISRGRTMIHIPGVRNSSSSTS 2244
            S     G  +  S  +      + +    +  + +   ++S       IP   ++ +S+S
Sbjct: 1082 SSTTADGTSMPTSTYSEGSTPLTSVPVSTRLVVSSEASTLSTTPVDTSIPVTTSTEASSS 1141

Query: 2245 PVSKKGPPLKTPASKSPSEGQTATTS-PRGAKPSVKSE-----LSPVARQTSQIGGSSKA 2298
            P + +G  + T     PSEG T   S P      V SE      +PV  +T Q+  S++A
Sbjct: 1142 PTTAEGTSIPT---SPPSEGTTPLASMPVSTTLVVSSEANTLSTTPVDSKT-QVATSTEA 1197

Query: 2299 PSRSGSRDSTPSRPAQQPLSR------------PIQSPGRNSISPGRNGISPPNKLSQLP 2346
             S   + + T S P   P  R            P+ S   +++S      S P   S   
Sbjct: 1198 SSPPPTAEVT-SMPTSTPGERSTPLTSMPVRHTPVASSEASTLSTSPVDTSTPVTTS-AE 1255

Query: 2347 RTSSPSTA-------STKSSGSGKMS--------YTSPGRQMSQQNLTKQTGLSKNASSI 2391
             +SSP+TA       ST S GS  ++         TSP             G    ++ +
Sbjct: 1256 TSSSPTTAEGTSLPTSTTSEGSTLLTSIPVSTTLVTSPEASTLLTTPVDTKGPVVTSNEV 1315

Query: 2392 PRSESASKGLNQMNN--GNGANKKVELSRMSSTKSSGSESDRSERPV----LVRQSTFIK 2445
              S + ++G +   +    G      +   ++  +S + S  S  PV     V  ST   
Sbjct: 1316 SSSPTPAEGTSMPTSTYSEGRTPLTSIPVNTTLVASSAISILSTTPVDNSTPVTTSTEAC 1375

Query: 2446 EAPSPTLRRKLEESASFESLSP-SSRPASPT---RSQAQTPVLSPSLPDMSLSTHSSVQA 2501
             +P+ +    +  S   E  +P +S P S T    S+A T  LS +  D S    +S +A
Sbjct: 1376 SSPTTSEGTSMPNSNPSEGTTPLTSIPVSTTPVVSSEAST--LSATPVDTSTPGTTSAEA 1433

Query: 2502 GGWRKLPPNLS-PTIEYNDGR------PAKRHDIARSHSESPSRLPINRSGTWKREHSKH 2554
                     +S PT   ++G+      P     +A S + + S  P++ +       +  
Sbjct: 1434 TSSPTTAEGISIPTSTPSEGKTPLKSIPVSNTPVANSEASTLSTTPVDSNSPVVTSTAVS 1493

Query: 2555 SSSLPRVSTWRRTGSSSSILSASSESSEKAKSEDEKHVNSISGT-----------KQSKE 2603
            SS  P   T     + S   +A +       +     +NS+S T            Q+  
Sbjct: 1494 SSPTPAEGTSIAISTPSEGSTALTSIPVSTTTVASSEINSLSTTPAVTSTPVTTYSQASS 1553

Query: 2604 NQVSAKGTWRKIKENEFSPTNSTSQTVSSGATNGAESKTLIYQMAPAVSKTEDVWVRIED 2663
            +  +A GT  +        T  TS  VS+     +E+ TL     P  SKT+       +
Sbjct: 1554 SPTTADGTSMQTSTYSEGSTPLTSLPVSTMLVVSSEANTL--STTPIDSKTQ--VTASTE 1609

Query: 2664 CPINNPRSGRSPTGNTPPVIDSVSEKANPNIKDSKDNQAKQNVGNGSVPMRTVGLENRLN 2723
               +    G S T +TP        + +P +               S+P+ T        
Sbjct: 1610 ASSSTTAEGSSMTISTP-------SEGSPLLT--------------SIPVSTT------- 1641

Query: 2724 SFIQVDAPDQKGTEIKPGQNNPVPVSETNESSI---VERTPFSSSSSSKHSSPSGTVAAR 2780
                V +P+       P  +N   ++ T  SS     E T   +S+ ++  +P  ++  R
Sbjct: 1642 ---PVASPEASTLSTTPVDSNSPVITSTEVSSSPTPAEGTSMPTSTYTEGRTPLTSITVR 1698

Query: 2781 VTPFNYNPSPRKSSADST-SARPSQIPTPVNNNTKKRDSKTDSTESSGTQSP 2831
             TP         SSA ST S  P    TPV  +T+ R S    T S GT  P
Sbjct: 1699 TTPV-------ASSAISTLSTTPVDNSTPVTTSTEARSS---PTTSEGTSMP 1740



 Score = 81.6 bits (200), Expect = 1e-14
 Identities = 339/1720 (19%), Positives = 594/1720 (34%), Gaps = 207/1720 (12%)

Query: 1200 SSSGQSSKTEHMSSSSENTSTPSSNAKRQNQLHPSSAQSRSGQPQKAATCKVSSINQETI 1259
            S+ G SS T     +S  TSTPS        +  S+    S +    +T  V S  Q T 
Sbjct: 2019 STEGSSSPTT-AGGTSIQTSTPSERTTPLAGMPVSTTLVVSSEGNTLSTTPVDSKTQVTN 2077

Query: 1260 QTYC-----VEDTPICFSRCSSLSSLSSAEDEIGCNQTTQEADSANTLQIAEIKEKIGTR 1314
             T        E + +  S  S  S L ++   I  + T   +  A+TL    +       
Sbjct: 2078 STEASSSATAEGSSMTISAPSEGSPLLTS---IPLSTTPVASPEASTLSTTPV------- 2127

Query: 1315 SAEDPVSEVPAVSQHP-RTKSSRLQGSSLSSESARHKAVEFSSG--AKSPSKSGAQTPKS 1371
             +  PV     VS  P  T+ + +Q S+ S       ++  S+   A S   + + TP  
Sbjct: 2128 DSNSPVITSTEVSSSPIPTEGTSMQTSTYSDRRTPLTSMPVSTTVVASSAISTLSTTPVD 2187

Query: 1372 PPEHYVQETPLMFSRCTSVSSLDSFESRSIASSVQSEPCSGMVSGIISPSDLPDSPGQTM 1431
                    T    S  TS       E  S+ +S  SE  +   S  +S   +  S   T+
Sbjct: 2188 TSTPVTNSTEARSSPTTS-------EGTSMPTSTPSEGSTPFTSMPVSTMPVVTSEASTL 2240

Query: 1432 PPSRSKTPPPPPQTAQTKREVPKNKAPTAEKRESGPKQAAVNAAVQRVQVLPDADTLLHF 1491
                S TP        T  E     +PT  +  S P  + ++     +  +P + TL+  
Sbjct: 2241 ----SATPVDTSTPVTTSTEA--TSSPTTAEGTSIPT-STLSEGTTPLTSIPVSHTLVAN 2293

Query: 1492 ATESTPDGFSCSSSLSALSLDEPFIQKDVELRIMPPVQENDNGNETESEQPKESNENQEK 1551
            +  ST        S + +  + PF     E    PP  E  +   + S +          
Sbjct: 2294 SEVST-------LSTTPVDSNTPFTTS-TEASSPPPTAEGTSMPTSTSSEGNTPLTRMPV 2345

Query: 1552 EAEKTIDSEKDLLDDSDDDDIEILEECIISAMPTKSSRKAKKPAQTASKLPPPVARKP-S 1610
                    E   L  +  D    +     +     ++     P  T S+   P+   P S
Sbjct: 2346 STTMVASFETSTLSTTPADTSTPVTTYSQAGSSPTTADDTSMPTSTYSEGSTPLTSVPVS 2405

Query: 1611 QLPVYKLLPSQNRLQPQKHVSFTPGDDMPRVYCVEGTPINFSTATSLSDLTIE------S 1664
             +PV     S +        S TP D          TP+  ST  S S  T E      S
Sbjct: 2406 TMPVVSSEASTH--------STTPVDT--------STPVTTSTEASSSPTTAEGTSIPTS 2449

Query: 1665 PPNE----LAAGEGVRGGAQSGEFEKRDTIPTEGRSTDEAQGGKTSSVTIPE---LDDNK 1717
            PP+E    LA+         S E     T P +  +        +SS T  E   +  + 
Sbjct: 2450 PPSEGTTPLASMPVSTTPVVSSEAGTLSTTPVDTSTPMTTSTEASSSPTTAEDIVVPIST 2509

Query: 1718 AEEGDILAECINS-----AMPKGKSHKPFRVKK---IMDQVQQASASSSAPNKNQLDGKK 1769
            A EG  L   I       A P+  +     V     ++   + +S+++SA   +      
Sbjct: 2510 ASEGSTLLTSIPVSTTPVASPEASTLSTTPVDSNSPVVTSTEISSSATSAEGTSMPTSTY 2569

Query: 1770 KKPTSPVKPIPQNTEYRTRVRKNADSKNNLNAERVFSDNKDSKKQNLKNNSKVFNDKLPN 1829
             + ++P++ +P +T+       +  S   ++     + + ++                P+
Sbjct: 2570 SEGSTPLRSMPVSTKPLASSEASTLSTTPVDTSIPVTTSTETSSSPTTAKDTSMPISTPS 2629

Query: 1830 NEDRVRGSFAFDSPHHYTPIEGTPYCFSRNDSLSSLDFD-------DDDVDLSREKAELR 1882
                   S           +   P   S   +LS+   D             S   AE  
Sbjct: 2630 EVSTSLTSIL---------VSTMPVASSEASTLSTTPVDTRTLVTTSTGTSSSPTTAEGS 2680

Query: 1883 KAKENKESEAKVTSHTELTSNQQSAN-KTQAIAKQPINRGQPKPILQKQSTFPQSSKDIP 1941
                +   E        L S    AN +   ++  P++   P     + S+ P +++   
Sbjct: 2681 SMPTSTPGERSTPLTNILVSTTLLANSEASTLSTTPVDTSTPVTTSAEASSSPTTAEGTS 2740

Query: 1942 DRGAATDE---KLQNFAIENTPVCFSHNSSLSSLS-DIDQENNNKENEPIKETEPPDSQG 1997
             R +   +    L +  +   PV  S  S++S+ + D               T    +  
Sbjct: 2741 MRISTPSDGSTPLTSILVSTLPVASSEASTVSTTAVDTSIPVTTSTEASSSPTTAEVTSM 2800

Query: 1998 EPSKPQASGYAPKSFHVEDTPVCFSRNSSLSSLSIDSEDDLLQECISSAMPKKKKPSRLK 2057
              S P  +     S  V  TPV  S   +LS+  +D+        ++++      P+  +
Sbjct: 2801 PTSTPSETSTPLTSMPVNHTPVASSEAGTLSTTPVDTSTP-----VTTSTKASSSPTTAE 2855

Query: 2058 GDNEKHSPRNMGGILGEDLTLDLKDIQRP----------DSEHGLSPDSENFDWKAIQEG 2107
            G     S  + G  L   + +    +             D+   ++  +E        EG
Sbjct: 2856 GIVVPISTASEGSTLLTSIPVSTTPVASSEASTLSTTPVDTSIPVTTSTEGSSSPTTAEG 2915

Query: 2108 ANSIVSSLHQAAA---AACLSRQASSDSDSILSLKSGISLGSPFHLTPDQEEKPFTSN-K 2163
             +  +S+  + +    +  +S    + S++     + +   +P   + +    P T+   
Sbjct: 2916 TSMPISTPSEVSTPLTSILVSTVPVAGSEASTLSTTPVDTRTPVTTSAEASSSPTTAEGT 2975

Query: 2164 GPRILKPGEKSTLETKK-------IESESKGIKGGKKVYKSLITGKVRSNS-----EISG 2211
               I  PGE+ T  T           SE+  +        + +T    ++S     E +G
Sbjct: 2976 SMPISTPGERRTPLTSMSVSTMPVASSEASTLSRTPADTSTPVTTSTEASSSPTTAEGTG 3035

Query: 2212 -QMKQPLQANMP--SISRGRTMIHIPGVRNSSSSTSPVSKKGPPL---KTPASKSPSEGQ 2265
              +  P + + P  SI    T + IP    S+ ST+PV    P +   +  +S +P+EG 
Sbjct: 3036 IPISTPSEGSTPLTSIPVSTTPVAIPEA--STLSTTPVDSNSPVVTSTEVSSSPTPAEGT 3093

Query: 2266 TA--TTSPRGAKPSVKSELSPVARQTSQIGGSSKAPSRSGSRDSTPSRPAQQPLSRPIQS 2323
            +   +T   G+ P     +S     +S I   S  P  +    STP   + +  S P  S
Sbjct: 3094 SMPISTYSEGSTPLTGVPVSTTPVTSSAISTLSTTPVDT----STPVTTSTEAHSSPTTS 3149

Query: 2324 PGRNSISPGRNGISPPNKLSQLPRTSSPSTASTKSSGSGKMSYTSPGRQMSQQNLTKQTG 2383
             G +  +   +  S P  L+ +P ++    +S  S+ S     TS     S +  +  T 
Sbjct: 3150 EGTSMPTSTPSEGSTP--LTYMPVSTMLVVSSEDSTLSATPVDTSTPVTTSTEATSSTTA 3207

Query: 2384 LSKNASSIPRSESASKGLNQMNNGNGANKKVELSRMSSTKSSGSESDRSERPVLVRQSTF 2443
                 +SIP S + S+G+  + +   +N  V  S  S   ++  +S+       +  ST 
Sbjct: 3208 ---EGTSIPTS-TPSEGMTPLTSVPVSNTPVASSEASILSTTPVDSNTP-----LTTSTE 3258

Query: 2444 IKEAPSPTLRRKLEESASFESLSP-SSRPASPTR-SQAQTPVLSPSLPDMSLSTHSSVQA 2501
               +P       +  S   E  +P +S P S T  + ++T  LS +  D S    +  QA
Sbjct: 3259 ASSSPPTAEGTSMPTSTPSEGSTPLTSMPVSTTTVASSETSTLSTTPADTSTPVTTYSQA 3318

Query: 2502 GGWRKLPPNLS-PTIEYNDGRPAKRHDIARSHSESPSRLPINRSGTWKREHSKHSSSLPR 2560
                 +    S PT  Y++G            S   + +  + +     E S  S++   
Sbjct: 3319 SSSPPIADGTSMPTSTYSEG------------STPLTNMSFSTTPVVSSEASTLSTTPVD 3366

Query: 2561 VSTWRRTGSSSSILSASSESSEKAKSEDEKHVNSISGTKQSKENQVSAKGTWRKIKENEF 2620
             ST   T + +S+   ++E +    S   +    ++    S    VS++        N  
Sbjct: 3367 TSTPVTTSTEASLSPTTAEGTSIPTSSPSEGTTPLASMPVSTTPVVSSE-------VNTL 3419

Query: 2621 SPTNSTSQTVSSGATNGAESKTLIYQMAPAVSKTEDVWVRIEDCPINNP--RSGRSPTGN 2678
            S T   S T+ + +T  + S T+    +   S T +    +   P++     S  + T +
Sbjct: 3420 STTPVDSNTLVTTSTEASSSPTIAEGTSLPTSTTSEGSTPLSIMPLSTTPVASSEASTLS 3479

Query: 2679 TPPVIDSVSEKANPNIKDSKDNQAKQNVGNGSVPMRTVGLENRLNSFIQVDAPDQKGTEI 2738
            T PV     + + P    S  N +       S+P  T G               +  T +
Sbjct: 3480 TTPV-----DTSTPVTTSSPTNSSPTTAEVTSMPTSTAG---------------EGSTPL 3519

Query: 2739 K--PGQNNPVPVSETNESSI--VERTPFSSSSSSKHSSPSG---TVAARVTPFNYNPSPR 2791
               P    PV  SE +  S   V+   F +SSS   SSP+    T     TP   + S  
Sbjct: 3520 TNMPVSTTPVASSEASTLSTTPVDSNTFVTSSSQASSSPATLQVTTMRMSTPSEGSSSLT 3579

Query: 2792 KSSADSTSARPSQIPTPVNNNTKKRDSKTDSTESSGTQSP 2831
                 ST    S+  TP   +  +    T ST+S+ T +P
Sbjct: 3580 TMLLSSTYVTSSEASTPSTPSVDRSTPVTTSTQSNSTPTP 3619



 Score = 79.7 bits (195), Expect = 4e-14
 Identities = 335/1756 (19%), Positives = 608/1756 (34%), Gaps = 218/1756 (12%)

Query: 1176 PIDYSLKYATDIPSSQKQSFSFSKSSSGQSSKTEHMSSSSENTSTPSSN-----AKRQNQ 1230
            P+  S + ++   +++  S   S +S G +  T    S++  TS  +S         +  
Sbjct: 1249 PVTTSAETSSSPTTAEGTSLPTSTTSEGSTLLTSIPVSTTLVTSPEASTLLTTPVDTKGP 1308

Query: 1231 LHPSSAQSRSGQPQKAATCKVSSINQ-ETIQTYCVEDTPICFSRCSSLSSLSSAEDEIGC 1289
            +  S+  S S  P +  +   S+ ++  T  T    +T +  S   S+ S +  ++    
Sbjct: 1309 VVTSNEVSSSPTPAEGTSMPTSTYSEGRTPLTSIPVNTTLVASSAISILSTTPVDNSTPV 1368

Query: 1290 NQTTQEADSANTLQIAEIKEKIGTRSAED----PVSEVPAVSQHPRTKSSRLQGSSL--- 1342
              +T+   S  T +   +     +         PVS  P VS    T S+    +S    
Sbjct: 1369 TTSTEACSSPTTSEGTSMPNSNPSEGTTPLTSIPVSTTPVVSSEASTLSATPVDTSTPGT 1428

Query: 1343 -SSESARHKAVEFSSGAKSPSKSGAQTP-KSPPEHYVQETPLMFSRCTSVSS--LDSFES 1398
             S+E+             + + S  +TP KS P   V  TP+  S  +++S+  +DS   
Sbjct: 1429 TSAEATSSPTTAEGISIPTSTPSEGKTPLKSIP---VSNTPVANSEASTLSTTPVDSNSP 1485

Query: 1399 RSIASSVQSEP--CSGMVSGIISPSDLPDSPGQTMPPSRSKTPPPPPQTAQTKREVPKNK 1456
               +++V S P    G    I +PS+   +   ++P S +        +  T   V    
Sbjct: 1486 VVTSTAVSSSPTPAEGTSIAISTPSE-GSTALTSIPVSTTTVASSEINSLSTTPAVTSTP 1544

Query: 1457 APTAEKRESGPKQA--------AVNAAVQRVQVLPDADTLLHFATESTPDGFSCSSSLSA 1508
              T  +  S P  A          +     +  LP +  L+  +  +T       S    
Sbjct: 1545 VTTYSQASSSPTTADGTSMQTSTYSEGSTPLTSLPVSTMLVVSSEANTLSTTPIDSKTQV 1604

Query: 1509 LSLDEPFIQKDVELRIMPPVQENDNGNETESEQPKESNENQEKEAEKT----IDSEKDLL 1564
             +  E       E   M  +     G+   +  P  +      EA       +DS   ++
Sbjct: 1605 TASTEASSSTTAEGSSMT-ISTPSEGSPLLTSIPVSTTPVASPEASTLSTTPVDSNSPVI 1663

Query: 1565 DDSDDDDIEILEECIISAMPTKSSRKAKKPAQTASKLPPPVARKP----SQLPVYKLLPS 1620
              ++        E   ++MPT +  + + P  + +    PVA       S  PV    P 
Sbjct: 1664 TSTEVSSSPTPAEG--TSMPTSTYTEGRTPLTSITVRTTPVASSAISTLSTTPVDNSTPV 1721

Query: 1621 QNRLQPQKHVSFTPGDDMPRVYCVEGT------PINFSTATSLSDLTIESPPNELAAGEG 1674
                + +   + + G  MP     EGT      P++ +   S    T+ + P + +    
Sbjct: 1722 TTSTEARSSPTTSEGTSMPNSTPSEGTTPLTSIPVSTTPVLSSEASTLSATPIDTSTPVT 1781

Query: 1675 VRGGAQSGEFEKRDT-IPTEGRSTDEAQGGKTSSVTIPELDDNKAEEGDILAECINSAMP 1733
                A S       T IPT   S  E     TS+     L  N +E   +    ++S  P
Sbjct: 1782 TSTEATSSPTTAEGTSIPTSTLS--EGMTPLTSTPVSHTLVAN-SEASTLSTTPVDSNSP 1838

Query: 1734 KGKSHKPFRVKKIMDQVQQASASSSAPNKNQLDGKKKKPTSPVKPIPQNTEYRTRVRKNA 1793
                            V  ++A SS+P     +G     ++P +     T         A
Sbjct: 1839 ----------------VVTSTAVSSSPTP--AEGTSIATSTPSEGSTALTSIPVSTTTVA 1880

Query: 1794 DSKNNL--NAERVFSDNKDSKKQNLKNNSKVFNDKLPNNEDRVRGSFAFDSPHHYTPIEG 1851
             S+ N       V S    +  Q   + +      +P +  R         P    P+  
Sbjct: 1881 SSETNTLSTTPAVTSTPVTTYAQVSSSPTTADGSSMPTSTPREGRP-----PLTSIPVST 1935

Query: 1852 TPYCFSRNDSLSSLDFDDDDVDLSREKAELRKAKENKES---EAKVTSHTELTSNQQS-- 1906
            T    S  ++LS+   D      +  +A       +  S    A     T LTS   S  
Sbjct: 1936 TTVASSEINTLSTTLADTRTPVTTYSQASSSPTTADGTSMPTPAYSEGSTPLTSMPLSTT 1995

Query: 1907 ---ANKTQAIAKQPINRGQPKPILQKQSTFPQSSKDIPDRGAATDEK---LQNFAIENTP 1960
               +++   ++  P++   P     + S+ P ++     + +   E+   L    +  T 
Sbjct: 1996 LVVSSEASTLSTTPVDTSTPATTSTEGSSSPTTAGGTSIQTSTPSERTTPLAGMPVSTTL 2055

Query: 1961 VCFSHNSSLSSLSDIDQENNNKENEPIKETEPPDSQGEPSKPQASGYAPKSFHVEDTPVC 2020
            V  S  ++LS+     +       E         S    S P        S  +  TPV 
Sbjct: 2056 VVSSEGNTLSTTPVDSKTQVTNSTEASSSATAEGSSMTISAPSEGSPLLTSIPLSTTPVA 2115

Query: 2021 FSRNSSLSSLSIDSEDDLLQ--ECISSAMPKKKKPSRLKGDNEKHSPRN---MGGILGED 2075
                S+LS+  +DS   ++   E  SS +P +    +    +++ +P     +   +   
Sbjct: 2116 SPEASTLSTTPVDSNSPVITSTEVSSSPIPTEGTSMQTSTYSDRRTPLTSMPVSTTVVAS 2175

Query: 2076 LTLDLKDIQRPDSEHGLSPDSENFDWKAIQEGANSIVSSLHQAAAAACLSRQASSDSDSI 2135
              +        D+   ++  +E        EG +   S+  + +            S  +
Sbjct: 2176 SAISTLSTTPVDTSTPVTNSTEARSSPTTSEGTSMPTSTPSEGSTPFT--------SMPV 2227

Query: 2136 LSLKSGISLGSPFHLTPDQEEKPFTSNKGPRILKPGEKSTLETKKIESESKGIKGGKKVY 2195
             ++    S  S    TP     P T++           +T E   I + +   +G   + 
Sbjct: 2228 STMPVVTSEASTLSATPVDTSTPVTTSTEAT----SSPTTAEGTSIPTSTLS-EGTTPLT 2282

Query: 2196 KSLITGKVRSNSEISGQMKQPLQANMPSISRGRTMIHIPGVRNSSSSTSPVSKKGPPL-K 2254
               ++  + +NSE+S     P+ +N P  +        P    +S  TS  S+   PL +
Sbjct: 2283 SIPVSHTLVANSEVSTLSTTPVDSNTPFTTSTEASSPPPTAEGTSMPTSTSSEGNTPLTR 2342

Query: 2255 TPASK---SPSEGQTATTSPRGAKPSVKSELSPVARQTSQIGGSSKAPSRSGSRDSTPSR 2311
             P S    +  E  T +T+P        ++ S      SQ G S      +    ST S 
Sbjct: 2343 MPVSTTMVASFETSTLSTTP--------ADTSTPVTTYSQAGSSPTTADDTSMPTSTYSE 2394

Query: 2312 PAQQPLSRPIQSPGRNSISPGRNGISPPNKLSQLPRTSSPSTASTKSSGSGKMSYTSPGR 2371
             +    S P+ +    S     +  +P +  +  P T+S   +S+ ++  G    TSP  
Sbjct: 2395 GSTPLTSVPVSTMPVVSSEASTHSTTPVD--TSTPVTTSTEASSSPTTAEGTSIPTSP-- 2450

Query: 2372 QMSQQNLTKQTGLSKNASSIPRSESASKGLNQMNNGNGANKKVELSRMSSTKSSGSESDR 2431
                +  T    +  + + +  SE+          G  +   V+ S   +T +  S S  
Sbjct: 2451 --PSEGTTPLASMPVSTTPVVSSEA----------GTLSTTPVDTSTPMTTSTEASSSPT 2498

Query: 2432 SERPVLVRQSTFIKEAPSPTLRRKLEESASFESLSPSSRPASPTRSQAQTPVLSPSLPDM 2491
            +   ++V  ST    +   TL   +  S      +P + P + T S       SP +   
Sbjct: 2499 TAEDIVVPIST---ASEGSTLLTSIPVST-----TPVASPEASTLSTTPVDSNSPVVTST 2550

Query: 2492 SLSTHSSVQAGGWRKLPPNLSPTIEYNDG------RPAKRHDIARSHSESPSRLPI---- 2541
             +S+ ++   G          PT  Y++G       P     +A S + + S  P+    
Sbjct: 2551 EISSSATSAEG-------TSMPTSTYSEGSTPLRSMPVSTKPLASSEASTLSTTPVDTSI 2603

Query: 2542 --------NRSGTWKREHSKHSSSLPRVSTWRRTGSSSSILSASSESSEKAKS--EDEKH 2591
                    + S T  ++ S   S+   VST   +   S++  ASSE+S  + +  +    
Sbjct: 2604 PVTTSTETSSSPTTAKDTSMPISTPSEVSTSLTSILVSTMPVASSEASTLSTTPVDTRTL 2663

Query: 2592 VNSISGTKQSKENQVSAKGTWRKIKENEFSPTNSTSQTVSSGATNGAESKTLIYQMAPAV 2651
            V + +GT  S     +A+G+         S   ST    S+  TN   S TL+     + 
Sbjct: 2664 VTTSTGTSSS---PTTAEGS---------SMPTSTPGERSTPLTNILVSTTLLANSEAST 2711

Query: 2652 SKTEDVWVRIEDCPINNPRSGRSPTGNTPPVIDSVSEKANPNIKDSKDNQAKQNVGNGSV 2711
              T                   +P   + PV  S    ++P   +    +      +GS 
Sbjct: 2712 LST-------------------TPVDTSTPVTTSAEASSSPTTAEGTSMRI-STPSDGST 2751

Query: 2712 PMRTVGLENRLNSFIQVDAPDQKGTEIKPGQNNPVPVSETNESS----IVERTPFSSSSS 2767
            P+ ++     L S + V A  +  T      +  +PV+ + E+S      E T   +S+ 
Sbjct: 2752 PLTSI-----LVSTLPV-ASSEASTVSTTAVDTSIPVTTSTEASSSPTTAEVTSMPTSTP 2805

Query: 2768 SKHSSPSGTVAARVTPFNYNPSPRKSSADSTSARPSQIPTPVNNNTKKRDSKTDSTESSG 2827
            S+ S+P  ++     P N+ P    S A + S  P    TPV  +TK   S T + E   
Sbjct: 2806 SETSTPLTSM-----PVNHTP-VASSEAGTLSTTPVDTSTPVTTSTKASSSPT-TAEGIV 2858

Query: 2828 TQSPKRHSGSYLVTSV 2843
                    GS L+TS+
Sbjct: 2859 VPISTASEGSTLLTSI 2874



 Score = 75.9 bits (185), Expect = 5e-13
 Identities = 167/765 (21%), Positives = 282/765 (36%), Gaps = 88/765 (11%)

Query: 2125 SRQASSDS---DSILSLKSGISLGS-PFHLTPDQEEKPFTSNKGPRILKPGEKSTLETKK 2180
            S QASS     +S    KS  S GS P    P    K  +S     +  P E ST  T  
Sbjct: 191  STQASSSPTTPESTTIPKSTNSEGSTPLTSMPASTMKVASSEAITLLTTPVEISTPVTIS 250

Query: 2181 IESESKGIKG-GKKVYKSLITGKVRSNSEISGQMKQPLQANMPSISRGRTMIHIPGVRNS 2239
             ++ S      G  +  S  +G     + +   +   + +   ++S      +IP + ++
Sbjct: 251  AQASSSPTTAEGPSLSNSAPSGGSTPLTRMPLSVMLVVSSEASTLSTTPAATNIPVITST 310

Query: 2240 SSSTSPVSKKGPPLKTPASKSPSEGQTATTS-PRGAKPSVKSELSPVARQTSQIGGSSKA 2298
             +S+SP + +G  + T    + +EG T  TS P    P   SE+S +          S  
Sbjct: 311  EASSSPTTAEGTSIPT---STYTEGSTPLTSTPASTMPVATSEMSTL----------SIT 357

Query: 2299 PSRSGSRDSTPSRPAQQPLSRPIQSPGRNSISPGRNGISPPNKLSQLPRTSSPSTASTKS 2358
            P  + +  +T + P+  P +    S   +++S G   ++     + L  +S  ST ST  
Sbjct: 358  PVDTSTLVTTSTEPSSLPTTAEATSMLTSTLSEGSTPLTNMPVSTILVASSEASTTSTIP 417

Query: 2359 SGSGKMSYTSPGRQMSQQNLTKQTGLSKNASSIPRSESASKGLNQMNNGNGANKKVELSR 2418
              S K   T+     S     + T ++ +  S   +   S  ++     +     +  + 
Sbjct: 418  VDS-KTFVTTASEASSSPTTAEDTSIATSTPSEGSTPLTSMPVSTTPVASSEASNLSTTP 476

Query: 2419 MSSTKSSGSESDRSERPVLVRQSTFIKEAPSPTLRRKLEESASFESLSPSSRPASPTRSQ 2478
            + S     + ++ S  P     ++     PS       E S    S+S S+ P +   S+
Sbjct: 477  VDSKTQVTTSTEASSSPPTAEVNSMPTSTPS-------EGSTPLTSMSVSTMPVA--SSE 527

Query: 2479 AQTPVLSPSLPDMSLSTHSSVQAGGWRKLPPNLS-PTIEYNDG------RPAKRHDIARS 2531
            A T  LS +  D S    +S +A      P   S PT   ++G       P     +  S
Sbjct: 528  AST--LSTTPVDTSTPVTTSSEASSSSTTPEGTSIPTSTPSEGSTPLTNMPVSTRLVVSS 585

Query: 2532 HSESPSRLPINRSGTWKREHSKHSS--------SLPRVSTWRRTG------SSSSILSAS 2577
             + + S  P + S T+    S+ SS        S+P  ST+   G      S S+ L AS
Sbjct: 586  EASTTSTTPAD-SNTFVTTSSEASSSSTTAEGTSMP-TSTYSERGTTITSMSVSTTLVAS 643

Query: 2578 SESSEKAKSEDEKHVNSISGTKQSKENQVSAKGTWRKIKENEFSPTNSTSQTVSSGATNG 2637
            SE+S  + +  + +   ++ + ++  +  +A+GT           T  TS  V++     
Sbjct: 644  SEASTLSTTPVDSN-TPVTTSTEATSSSTTAEGTSMPTSTYTEGSTPLTSMPVNTTLVAS 702

Query: 2638 AESKTL----IYQMAPAVSKTE----DVWVRIEDCPINNPRSGRSP-----------TGN 2678
            +E+ TL    +    P  + TE             P + P  G +P           T +
Sbjct: 703  SEASTLSTTPVDTSTPVTTSTEASSSPTTADGASMPTSTPSEGSTPLTSMPVSKTLLTSS 762

Query: 2679 TPPVIDSVSEKANPNIKDSKDNQAKQNVGNG-SVPMRTVGLENRLNSFIQVDAPDQKGTE 2737
                + +     + +I  S +         G S+P+ T    + L + I V        E
Sbjct: 763  EASTLSTTPLDTSTHITTSTEASCSPTTTEGTSMPISTPSEGSPLLTSIPVSITPVTSPE 822

Query: 2738 IKPGQNNPVPVSETNESSIVERTPFSSSSSSKH--SSPSGTVAARVTPFNYNPSP----R 2791
                   PV     + S +   T  SSS +     S P+ T +   TP    P       
Sbjct: 823  ASTLSTTPV----DSNSPVTTSTEVSSSPTPAEGTSMPTSTYSEGRTPLTSMPVSTTLVA 878

Query: 2792 KSSADSTSARPSQIPTPVNNNTKKRDSKTDSTESSGTQSPKRHSG 2836
             S+  + S  P    TPV N+T+ R S    T S GT  P    G
Sbjct: 879  TSAISTLSTTPVDTSTPVTNSTEARSS---PTTSEGTSMPTSTPG 920



 Score = 72.0 bits (175), Expect = 8e-12
 Identities = 315/1667 (18%), Positives = 557/1667 (33%), Gaps = 203/1667 (12%)

Query: 1211 MSSSSENTSTPSSNAKRQNQLHPSSAQSRSGQPQKAATCKVSSINQETIQTYCVEDTPIC 1270
            +++S+E +S+P++       +   S  S S      +T  V+S    T+ T  V+   + 
Sbjct: 2605 VTTSTETSSSPTTAKDTSMPISTPSEVSTSLTSILVSTMPVASSEASTLSTTPVDTRTLV 2664

Query: 1271 FSRCSSLSSLSSAEDEIGCNQTTQEADSANTLQIAEIKEKIGTRSAEDPVSEVPAVSQHP 1330
             +   + SS ++AE       T+   + +  L    +   +   S    +S  P  +  P
Sbjct: 2665 TTSTGTSSSPTTAEGS--SMPTSTPGERSTPLTNILVSTTLLANSEASTLSTTPVDTSTP 2722

Query: 1331 RTKSSRLQGSSLSSESARHKAVEFSSGAKSPSKSGAQTPKSPPEHYVQETPLMFSRCTSV 1390
             T S+    S  ++E    +    S G+         TP +     V   P+  S  ++V
Sbjct: 2723 VTTSAEASSSPTTAEGTSMRISTPSDGS---------TPLT--SILVSTLPVASSEASTV 2771

Query: 1391 SSLDSFESRSIASSVQ--SEPCSGMVSGIISPSDLPD---SPGQTMPPSRSKTPPPPPQT 1445
            S+     S  + +S +  S P +  V+ +  P+  P    +P  +MP + +        T
Sbjct: 2772 STTAVDTSIPVTTSTEASSSPTTAEVTSM--PTSTPSETSTPLTSMPVNHTPVASSEAGT 2829

Query: 1446 AQTKREVPKNKAPTAEKRESGPKQAAVNAAVQRVQVLPDADTLL-HFATESTPDGFSCSS 1504
              T          T+ K  S P  A     V  +    +  TLL      +TP   S +S
Sbjct: 2830 LSTTPVDTSTPVTTSTKASSSPTTA--EGIVVPISTASEGSTLLTSIPVSTTPVASSEAS 2887

Query: 1505 SLSALSLDEPF-IQKDVELRIMPPVQENDNGNETESEQPKESNENQEKEAEKTID---SE 1560
            +LS   +D    +    E    P   E   G       P E +         T+    SE
Sbjct: 2888 TLSTTPVDTSIPVTTSTEGSSSPTTAE---GTSMPISTPSEVSTPLTSILVSTVPVAGSE 2944

Query: 1561 KDLLDDSDDDDIEILEECIISAMPTKSSRKAKKPAQTASKLPPPVARKPSQLPVYKLLPS 1620
               L  +  D          +  P  +S +A     TA     P++      P  +  P 
Sbjct: 2945 ASTLSTTPVD----------TRTPVTTSAEASSSPTTAEGTSMPIST-----PGERRTPL 2989

Query: 1621 QNRLQPQKHVSFTPGDDMPRVYCVEGTPINFSTATSLSDLTIESPPNELAAGEGVRGGAQ 1680
             +       V+ +    + R      TP+  ST  S S  T E        G G+     
Sbjct: 2990 TSMSVSTMPVASSEASTLSRTPADTSTPVTTSTEASSSPTTAE--------GTGIP---- 3037

Query: 1681 SGEFEKRDTIPTEGRSTDEAQGGKTSSVTIPELDDNKAEEGDILAECINSAMPKGKSHKP 1740
                    + P+EG +   +    T+ V IPE         D              S+ P
Sbjct: 3038 -------ISTPSEGSTPLTSIPVSTTPVAIPEASTLSTTPVD--------------SNSP 3076

Query: 1741 FRVKKIMDQVQQASASSSAPNKNQLDGKKKKPTSPVKPIP-QNTEYRTRVRKNADSKNNL 1799
                  +      +  +S P     +G       PV   P  ++   T      D+   +
Sbjct: 3077 VVTSTEVSSSPTPAEGTSMPISTYSEGSTPLTGVPVSTTPVTSSAISTLSTTPVDTSTPV 3136

Query: 1800 NAERVFSDNKDSKKQNLKNNSKVFNDKLPNNEDRVRGSFAF---DSPHHYTPIEGTPYCF 1856
                    +  + +      S       P     V         DS    TP++ +    
Sbjct: 3137 TTSTEAHSSPTTSEGTSMPTSTPSEGSTPLTYMPVSTMLVVSSEDSTLSATPVDTSTPVT 3196

Query: 1857 SRNDSLSSLDFDDDDVDLSREKAELRKAKENK-------ESEAKVTSHTELTSNQQSANK 1909
            +  ++ SS   +   +  S     +               SEA + S T + SN      
Sbjct: 3197 TSTEATSSTTAEGTSIPTSTPSEGMTPLTSVPVSNTPVASSEASILSTTPVDSNTPLTTS 3256

Query: 1910 TQAIAKQPINRGQPKPILQKQSTFPQSSKDIPDRGAATDEKLQNFAIENTPVCFSHNSSL 1969
            T+A +  P   G   P               P  G+     L +  +  T V  S  S+L
Sbjct: 3257 TEASSSPPTAEGTSMP------------TSTPSEGST---PLTSMPVSTTTVASSETSTL 3301

Query: 1970 SSLSDIDQENNNKENEPIKETEPPDSQGEPSKPQASGYAP-KSFHVEDTPVCFSRNSSLS 2028
            S+            ++        D    P+   + G  P  +     TPV  S  S+LS
Sbjct: 3302 STTPADTSTPVTTYSQASSSPPIADGTSMPTSTYSEGSTPLTNMSFSTTPVVSSEASTLS 3361

Query: 2029 SLSIDSEDDLLQECISSAMPKKKKPSRLKGDNEKHSPRNMGGILGEDLTLDLKDIQRPDS 2088
            +  +D+        ++++      P+  +G +   S  + G      + +    +     
Sbjct: 3362 TTPVDTSTP-----VTTSTEASLSPTTAEGTSIPTSSPSEGTTPLASMPVSTTPV----- 3411

Query: 2089 EHGLSPDSENFDWKAIQEGANSIVSSLHQAAAAACLSRQASSDSDSILSLKSGISLGSPF 2148
                   SE          +N++V++  +A+++  ++   S  + +     + +S+  P 
Sbjct: 3412 -----VSSEVNTLSTTPVDSNTLVTTSTEASSSPTIAEGTSLPTSTTSEGSTPLSI-MPL 3465

Query: 2149 HLTPDQEEKPFTSNKGPRILKPGEKSTLETKKIESESKGIKGGKKVYKSLITGKVRS-NS 2207
              TP               +   E STL T  +++ S  +        S  T +V S  +
Sbjct: 3466 STTP---------------VASSEASTLSTTPVDT-STPVTTSSPTNSSPTTAEVTSMPT 3509

Query: 2208 EISGQMKQPLQANMPSISRGRTMIHIPGVRNSSSSTSPV-SKKGPPLKTPASKSPSEGQT 2266
              +G+   PL  NMP      +   +     S+ ST+PV S       + AS SP+  Q 
Sbjct: 3510 STAGEGSTPL-TNMPV-----STTPVASSEASTLSTTPVDSNTFVTSSSQASSSPATLQ- 3562

Query: 2267 ATTSPRGAKPSVKSELSPVARQTSQIGGSSKAPSRSGSRDSTPSRPAQQPLSRPIQSPGR 2326
              T+ R + PS  S     +  T+ +  S+   S   S  STPS     P++   QS   
Sbjct: 3563 -VTTMRMSTPSEGS-----SSLTTMLLSSTYVTSSEASTPSTPSVDRSTPVTTSTQS--- 3613

Query: 2327 NSISPGRNGISPPNKLSQLPRTSSPSTASTKSSGSGKMSYTSPGRQMSQQNLTKQTGLSK 2386
            NS       I+ P  +S     S+P T    S+ S  +S       +     T     ++
Sbjct: 3614 NSTPTPPEVITLP--MSTPSEVSTPLTIMPVSTTSVTISEAGTASTLPVDTSTPVITSTQ 3671

Query: 2387 NASSIPRSESASKGLNQMNNGNGANKKVELSRMSSTKSSGSESDRSERPVLVRQSTFIKE 2446
             +SS    E  +  +   + G   +  +    +S+T+ + SE      P +V  +     
Sbjct: 3672 VSSSPVTPEGTTMPIWTPSEG---STPLTTMPVSTTRVTSSEGSTLSTPSVVTSTPVTTS 3728

Query: 2447 APSPTLRRKLEESASFESLSPSSRPASPTRSQAQTPVL------SPSLPDMSLSTHSSVQ 2500
              + +    L+ +    S+         T   + TPV       +PS+P +  S   +  
Sbjct: 3729 TEAISSSATLDSTTMSVSMPMEISTLGTTILVSTTPVTRFPESSTPSIPSVYTSMSMTTA 3788

Query: 2501 AGGWRKLPPNLSPTIEYNDGRPAKRHDIARSHSESP-SRLPINRSGTWKREHSKHSSSLP 2559
            + G    P  L  T        ++R  +  +   SP S +  + + T        S+ L 
Sbjct: 3789 SEG-SSSPTTLEGTTTMPMSTTSERSTLLTTVLISPISVMSPSEASTLSTPPGDTSTPL- 3846

Query: 2560 RVSTWRRTGSSSSILSAS----SESSEKAKSEDEKHVN-----SISGTKQSKENQVSAKG 2610
               T  + GS S     +    S +SE++       V+     S  G   +    +    
Sbjct: 3847 --LTSTKAGSFSIPAEVTTIRISITSERSTPLTTLLVSTTLPTSFPGASIASTPPLDTST 3904

Query: 2611 TWRKIKENEFSPTNSTSQTVS-SGATNGAESKTLIY-QMAPAVSKTEDVWVRIEDCPINN 2668
            T+    +   +PT   + T+S S  T G+   T I+    P  S T DV+          
Sbjct: 3905 TFTPSTDTASTPTIPVATTISVSVITEGSTPGTTIFIPSTPVTSSTADVF---------- 3954

Query: 2669 PRSGRSPTGNTPPVIDSVSEKANPNIKDSKDNQAKQNVGNGSVPMRTVGLENRLNSFIQV 2728
                 + TG     + + +E   P+   S    +       + P  T      L      
Sbjct: 3955 ----PATTGAVSTPVITSTELNTPSTSSSSTTTSFSTTKEFTTPAMTTAAP--LTYVTMS 4008

Query: 2729 DAPDQKGTEIKPGQNNPVPVSETN----ESSIVERTPFSSSSSSKHSSPSGTVAARVTPF 2784
             AP    T  +    +   +S T+     +S+  R    SS SS+ S+ +        P 
Sbjct: 4009 TAPSTPRTTSRGCTTSASTLSATSTPHTSTSVTTRPVTPSSESSRPSTITSHTIPPTFPP 4068

Query: 2785 NYNPSPRKSSADSTSARPSQIPTPVNNNTKKRDSKTDSTESSGTQSP 2831
             ++ +P  +SA ST+  P  + T +   TK     T     + T  P
Sbjct: 4069 AHSSTPPTTSASSTTVNPEAV-TTMTTRTKPSTRTTSFPTVTTTAVP 4114



 Score = 65.1 bits (157), Expect = 1e-09
 Identities = 205/1025 (20%), Positives = 347/1025 (33%), Gaps = 154/1025 (15%)

Query: 1898 TELTSNQQSANKTQAIAKQPINRGQPKPI----LQKQSTFPQSSKDIPDRGAATDEKLQN 1953
            T LTS   S   T  +A   ++     P+    L   ST P S   +P    AT      
Sbjct: 334  TPLTSTPAS---TMPVATSEMSTLSITPVDTSTLVTTSTEPSS---LPTTAEATSMLTST 387

Query: 1954 FAIENTPVC---------FSHNSSLSSLSDIDQEN--NNKENEPIKETEPPDSQGEPSKP 2002
             +  +TP+           S  +S +S   +D +             T   D+    S P
Sbjct: 388  LSEGSTPLTNMPVSTILVASSEASTTSTIPVDSKTFVTTASEASSSPTTAEDTSIATSTP 447

Query: 2003 QASGYAPKSFHVEDTPVCFSRNSSLSSLSIDSEDDLLQECISSAMPKKKK--------PS 2054
                    S  V  TPV  S  S+LS+  +DS+  +     +S+ P   +        PS
Sbjct: 448  SEGSTPLTSMPVSTTPVASSEASNLSTTPVDSKTQVTTSTEASSSPPTAEVNSMPTSTPS 507

Query: 2055 RLKGDNEKHSPRNMGGILGEDLTLDLKDIQRPD--------SEHGLSPDSENFDWKAIQE 2106
                     S   M     E  TL    +            S    +P+  +       E
Sbjct: 508  EGSTPLTSMSVSTMPVASSEASTLSTTPVDTSTPVTTSSEASSSSTTPEGTSIPTSTPSE 567

Query: 2107 GA----NSIVSSLHQAAAAACLSRQASSDSDSILSLKSGISLGS--------PFHLTPDQ 2154
            G+    N  VS+    ++ A  +    +DS++ ++  S  S  S        P     ++
Sbjct: 568  GSTPLTNMPVSTRLVVSSEASTTSTTPADSNTFVTTSSEASSSSTTAEGTSMPTSTYSER 627

Query: 2155 EEKPFTSNKGPRILKPGEKSTLETKKIESESKGIKGGKKVYKSLITGK---VRSNSEISG 2211
                 + +    ++   E STL T  ++S +  +    +   S  T +   + +++   G
Sbjct: 628  GTTITSMSVSTTLVASSEASTLSTTPVDSNTP-VTTSTEATSSSTTAEGTSMPTSTYTEG 686

Query: 2212 Q---MKQPLQANMPSISRGRTM------IHIPGVRNSSSSTSPVSKKGPPLKTPASKSPS 2262
                   P+   + + S   T+         P   ++ +S+SP +  G  + T    +PS
Sbjct: 687  STPLTSMPVNTTLVASSEASTLSTTPVDTSTPVTTSTEASSSPTTADGASMPT---STPS 743

Query: 2263 EGQTATTSPRGAKPSVKSELSPVARQTSQIGGSSKAPSRSGSRDSTPSRPAQQPLSRPIQ 2322
            EG T  TS   +K  + S  +     T     +    S   S   T +     P+S P +
Sbjct: 744  EGSTPLTSMPVSKTLLTSSEASTLSTTPLDTSTHITTSTEASCSPTTTEGTSMPISTPSE 803

Query: 2323 -SPGRNSISPGRNGISPP--NKLSQLP-RTSSPSTASTK-SSGSGKMSYTSPGRQMSQQN 2377
             SP   SI      ++ P  + LS  P  ++SP T ST+ SS       TS       + 
Sbjct: 804  GSPLLTSIPVSITPVTSPEASTLSTTPVDSNSPVTTSTEVSSSPTPAEGTSMPTSTYSEG 863

Query: 2378 LTKQTGLSKNASSIPRSESASKGLNQMNNGNGANKKVELSRMSSTKSSGSESDRSERPVL 2437
             T  T +  + + +  S  ++     ++         E +R S T S G+    S     
Sbjct: 864  RTPLTSMPVSTTLVATSAISTLSTTPVDTSTPVTNSTE-ARSSPTTSEGTSMPTSTPGEG 922

Query: 2438 VRQSTFIKEAPSPTLRRKLEESASFESLSPSSRPASPTRSQAQTPVLSPSLPDMSLSTHS 2497
                T + ++ +P              +S  +R  S T     TPV +      + +T S
Sbjct: 923  STPLTSMPDSTTPV-------------VSSEARTLSATPVDTSTPVTT-----STEATSS 964

Query: 2498 SVQAGGWRKLPPNLSPTIEYNDGRPAKRHDIARSHSESPSRLPI--NRSGTWKREHSKHS 2555
               A G        S         P     +A S + + S  P+  N   T   E S   
Sbjct: 965  PTTAEGTSIPTSTPSEGTTPLTSTPVSHTLVANSEASTLSTTPVDSNTPLTTSTEASSPP 1024

Query: 2556 SSLPRVSTWRRTGSS----------SSILSASSESSEKAKSEDEKHVNSISGTKQSKENQ 2605
             +    S    T S           S+ + ASSE+S  + +  +     ++   Q+  + 
Sbjct: 1025 PTAEGTSMPTSTPSEGSTPLTRMPVSTTMVASSETSTLSTTPADTS-TPVTTYSQASSSS 1083

Query: 2606 VSAKGTWRKIKENEFSPTNSTSQTVSSGATNGAESKTLIYQMAPAVSKTEDVWVRIEDCP 2665
             +A GT           T  TS  VS+     +E+ TL                      
Sbjct: 1084 TTADGTSMPTSTYSEGSTPLTSVPVSTRLVVSSEASTL---------------------- 1121

Query: 2666 INNPRSGRSPTGNTPPVIDSVSEKANPNIKDS----KDNQAKQNVGNGSVPMRT---VGL 2718
                    +P   + PV  S    ++P   +         ++      S+P+ T   V  
Sbjct: 1122 ------STTPVDTSIPVTTSTEASSSPTTAEGTSIPTSPPSEGTTPLASMPVSTTLVVSS 1175

Query: 2719 ENRLNSFIQVDAPDQKGTEIKPGQNNPVPVSETNESSIVERTPFSSSSSSKHSSPSGTVA 2778
            E    S   VD+  Q  T  +   ++P P +E         T   +S+  + S+P  ++ 
Sbjct: 1176 EANTLSTTPVDSKTQVATSTE--ASSPPPTAEV--------TSMPTSTPGERSTPLTSMP 1225

Query: 2779 ARVTPFNYNPSPRKSSADSTSARPSQIPTPVNNNTKKRDSKTDSTESSGTQSPKRHSGSY 2838
             R TP         S A + S  P    TPV  + +   S T + E +   +     GS 
Sbjct: 1226 VRHTPV------ASSEASTLSTSPVDTSTPVTTSAETSSSPT-TAEGTSLPTSTTSEGST 1278

Query: 2839 LVTSV 2843
            L+TS+
Sbjct: 1279 LLTSI 1283



 Score = 61.2 bits (147), Expect = 1e-08
 Identities = 286/1599 (17%), Positives = 542/1599 (33%), Gaps = 171/1599 (10%)

Query: 1171 RHVDQPIDYSLKYATDIPSSQKQSFSFSKSSSGQSSKT--EHMSSSSENTSTPSSNAKRQ 1228
            +    PI    + +T + S    +   + S +   S T  +  +  + +T T SS    +
Sbjct: 2619 KDTSMPISTPSEVSTSLTSILVSTMPVASSEASTLSTTPVDTRTLVTTSTGTSSSPTTAE 2678

Query: 1229 NQLHPSSAQSRSGQPQK---AATCKVSSINQETIQTYCVEDTPICFSRCSSLSSLSSAED 1285
                P+S       P      +T  +++    T+ T  V+ +    +   + SS ++AE 
Sbjct: 2679 GSSMPTSTPGERSTPLTNILVSTTLLANSEASTLSTTPVDTSTPVTTSAEASSSPTTAE- 2737

Query: 1286 EIGCNQTTQEADSANTLQIAEIKEKIGTRSAEDPVSEVPAVSQH-PRTKSSRLQGSSLSS 1344
              G +         +T   + +   +   S+E       AV    P T S+    S  ++
Sbjct: 2738 --GTSMRISTPSDGSTPLTSILVSTLPVASSEASTVSTTAVDTSIPVTTSTEASSSPTTA 2795

Query: 1345 ESARHKAVEFSSGAKSPSKSGAQTPKSPPEHYVQETPLMFSRCTSVSSLDSFESRSIASS 1404
            E         S    +PS++       P  H    TP+  S   ++S+     S  + +S
Sbjct: 2796 EVT-------SMPTSTPSETSTPLTSMPVNH----TPVASSEAGTLSTTPVDTSTPVTTS 2844

Query: 1405 VQSEPCSGMVSGIISPSDLPDSPGQTMPPSRSKTPPPPPQTAQTKREVPKNKA-PTAEKR 1463
             ++        GI+ P          +      T P     A T    P + + P     
Sbjct: 2845 TKASSSPTTAEGIVVPISTASEGSTLLTSIPVSTTPVASSEASTLSTTPVDTSIPVTTST 2904

Query: 1464 ESGPKQAAVNAAVQRVQVLPDADT-LLHFATESTPDGFSCSSSLSALSLD-EPFIQKDVE 1521
            E              +    +  T L      + P   S +S+LS   +D    +    E
Sbjct: 2905 EGSSSPTTAEGTSMPISTPSEVSTPLTSILVSTVPVAGSEASTLSTTPVDTRTPVTTSAE 2964

Query: 1522 LRIMPPVQENDNGNETESEQPKESNENQEKEAEKTIDSEKDLLDDSD-DDDIEILEECII 1580
                P   E  +   +   + +    +          SE   L  +  D    +      
Sbjct: 2965 ASSSPTTAEGTSMPISTPGERRTPLTSMSVSTMPVASSEASTLSRTPADTSTPVTTSTEA 3024

Query: 1581 SAMPTKSSRKA---KKPAQTASKLPP-PVARKPSQLPVYKLL-----PSQNRLQPQKHVS 1631
            S+ PT +         P++ ++ L   PV+  P  +P    L      S + +     VS
Sbjct: 3025 SSSPTTAEGTGIPISTPSEGSTPLTSIPVSTTPVAIPEASTLSTTPVDSNSPVVTSTEVS 3084

Query: 1632 FTP----GDDMPRVYCVEGT------PINFSTATSLSDLTIESPPNELAAGEGVRGGAQS 1681
             +P    G  MP     EG+      P++ +  TS +  T+ + P + +           
Sbjct: 3085 SSPTPAEGTSMPISTYSEGSTPLTGVPVSTTPVTSSAISTLSTTPVDTSTPV-------- 3136

Query: 1682 GEFEKRDTIPTEGRSTDEAQGGKTSSVTIPELDDNKAEEGDILAECINSAMPKGKSHKPF 1741
                   T  TE  S+     G +   + P           +    + S+     S  P 
Sbjct: 3137 -------TTSTEAHSSPTTSEGTSMPTSTPSEGSTPLTYMPVSTMLVVSSEDSTLSATPV 3189

Query: 1742 RVKKIMDQVQQASASSSAPNKNQLDGKKKKPTSPVKPIPQNTEYRTRVRKNADSKNNLNA 1801
                 +    +A++S++A   +       +  +P+  +P +         +  S   +++
Sbjct: 3190 DTSTPVTTSTEATSSTTAEGTSIPTSTPSEGMTPLTSVPVSNTPVASSEASILSTTPVDS 3249

Query: 1802 ERVFSDNKDSKKQNLKNNSKVFNDKLPNNEDRVRGSFAFDSPHHYTPIEGTPYCFSRNDS 1861
                + + ++                P+      GS    +P    P+  T    S   +
Sbjct: 3250 NTPLTTSTEASSSPPTAEGTSMPTSTPS-----EGS----TPLTSMPVSTTTVASSETST 3300

Query: 1862 LSSLDFDDDDVDLSREKAELRKAKENKESEAKVT---SHTELTSNQQS-----ANKTQAI 1913
            LS+   D      +  +A       +  S    T     T LT+   S     +++   +
Sbjct: 3301 LSTTPADTSTPVTTYSQASSSPPIADGTSMPTSTYSEGSTPLTNMSFSTTPVVSSEASTL 3360

Query: 1914 AKQPINRGQPKPILQKQSTFPQSSKDIPDRGAATDE---KLQNFAIENTPVCFSHNSSLS 1970
            +  P++   P     + S  P +++      ++  E    L +  +  TPV    +S ++
Sbjct: 3361 STTPVDTSTPVTTSTEASLSPTTAEGTSIPTSSPSEGTTPLASMPVSTTPVV---SSEVN 3417

Query: 1971 SLSDIDQENNNKENEPIKETEPP---DSQGEPSKPQASGYAPKS-FHVEDTPVCFSRNSS 2026
            +LS    ++N       + +  P   +    P+   + G  P S   +  TPV  S  S+
Sbjct: 3418 TLSTTPVDSNTLVTTSTEASSSPTIAEGTSLPTSTTSEGSTPLSIMPLSTTPVASSEAST 3477

Query: 2027 LSSLSIDSEDDLLQECISSAMPKKKKPSRLKGDNEKHSPRNMGGILGEDLTLDLKDIQRP 2086
            LS+  +D+        ++++ P    P+  +  +   S    G     ++ +    +   
Sbjct: 3478 LSTTPVDTSTP-----VTTSSPTNSSPTTAEVTSMPTSTAGEGSTPLTNMPVSTTPV--- 3529

Query: 2087 DSEHGLSPDSENFDWKAIQEGANSIVSSLHQAAAAAC----LSRQASSDSDSILSLKSGI 2142
                     SE          +N+ V+S  QA+++       + + S+ S+   SL +  
Sbjct: 3530 -------ASSEASTLSTTPVDSNTFVTSSSQASSSPATLQVTTMRMSTPSEGSSSLTT-- 3580

Query: 2143 SLGSPFHLTPDQEEKPFTSNKGPRILKPGEKSTLETKKIESESKGIKGGKKVYKSLITGK 2202
             L S  ++T  +   P T +         ++ST  T   +S S            +IT  
Sbjct: 3581 MLLSSTYVTSSEASTPSTPSV--------DRSTPVTTSTQSNS------TPTPPEVITLP 3626

Query: 2203 VRSNSEISGQMK-QPLQANMPSISRGRTMIHI------PGVRNSSSSTSPVSKKGPPLKT 2255
            + + SE+S  +   P+     +IS   T   +      P + ++  S+SPV+ +G    T
Sbjct: 3627 MSTPSEVSTPLTIMPVSTTSVTISEAGTASTLPVDTSTPVITSTQVSSSPVTPEG---TT 3683

Query: 2256 PASKSPSEGQT-ATTSPRGAKPSVKSELS----PVARQTSQIGGSSKAPSRSGSRDSTPS 2310
                +PSEG T  TT P        SE S    P    ++ +  S++A S S + DST  
Sbjct: 3684 MPIWTPSEGSTPLTTMPVSTTRVTSSEGSTLSTPSVVTSTPVTTSTEAISSSATLDST-- 3741

Query: 2311 RPAQQPLSRPIQSPGRNSISPGRNGISPPNKLSQLPRTSSPSTAS--------TKSSGSG 2362
                  +S P++       + G   +     +++ P +S+PS  S        T S GS 
Sbjct: 3742 ---TMSVSMPMEIS-----TLGTTILVSTTPVTRFPESSTPSIPSVYTSMSMTTASEGSS 3793

Query: 2363 KMSYTSPGRQMSQQNLTKQTGLSKNASSIPRSESASKGLNQMNNGNGANKKVELSRMSST 2422
              +       M     ++++ L       P S  +    + ++   G         ++ST
Sbjct: 3794 SPTTLEGTTTMPMSTTSERSTLLTTVLISPISVMSPSEASTLSTPPG---DTSTPLLTST 3850

Query: 2423 KSSGSESDRSERPVLVRQSTFIKEAPSPTLRRKLEESASFESLSPSSRPA-------SPT 2475
            K +GS S  +E   +    T  +  P  TL        SF   S +S P        +P+
Sbjct: 3851 K-AGSFSIPAEVTTIRISITSERSTPLTTLLVSTTLPTSFPGASIASTPPLDTSTTFTPS 3909

Query: 2476 RSQAQTPVLSPSLPDMSLSTHSSVQAGGWRKLPPNLSPTIEYNDGRPAKRHDIARSHSES 2535
               A TP + P    +S+S  +     G     P+   T    D  PA    ++     S
Sbjct: 3910 TDTASTPTI-PVATTISVSVITEGSTPGTTIFIPSTPVTSSTADVFPATTGAVSTPVITS 3968

Query: 2536 PSRLPINRSGTWKREHSKHSSSLPRVSTWRRTGSSSSILSASSESSEKAKSEDEKHVNSI 2595
                 +N   T     +   S+    +T   T ++       S +    ++       S 
Sbjct: 3969 TE---LNTPSTSSSSTTTSFSTTKEFTTPAMTTAAPLTYVTMSTAPSTPRTTSRGCTTSA 4025

Query: 2596 SGTKQSKENQVSAKGTWRKIKENEFS--PTNSTSQTVSSGATNGAESKTLIYQMAPAVSK 2653
            S    +     S   T R +  +  S  P+  TS T+       A S T     A + + 
Sbjct: 4026 STLSATSTPHTSTSVTTRPVTPSSESSRPSTITSHTIPP-TFPPAHSSTPPTTSASSTTV 4084

Query: 2654 TEDVWVRIEDCPINNPRSGRSPTGNTPPVIDSVSEKANP 2692
              +    +      + R+   PT  T  V  + + K+NP
Sbjct: 4085 NPEAVTTMTTRTKPSTRTTSFPTVTTTAVPTNTTIKSNP 4123


>gi|42542379 serine/arginine repetitive matrix 1 [Homo sapiens]
          Length = 904

 Score = 73.2 bits (178), Expect = 4e-12
 Identities = 108/511 (21%), Positives = 184/511 (36%), Gaps = 51/511 (9%)

Query: 2218 QANMPSISRGRTMIHIPGVRNSSSSTSPVSKKGPPLKTPASKSPSEGQTATTSPRGAKPS 2277
            ++  P   R R+   + G   SSSS+S    + PP K P   S    +T   SP  + P 
Sbjct: 340  RSRSPVRRRRRSSASLSG---SSSSSSSSRSRSPPKKPPKRTSSPPRKTRRLSPSASPPR 396

Query: 2278 VKSELSPVARQTSQIGGSSKAPSRSGSRDSTPSRPAQQPLSRPIQSPGRNSISPGRN-GI 2336
             +   SP A            P        TP +  +   SR   SPGR S    ++ G 
Sbjct: 397  RRHRPSPPA-----------TPPPKTRHSPTPQQSNRTRKSRVSVSPGRTSGKVTKHKGT 445

Query: 2337 SPPNKLSQLPRTSSPSTASTKSSGSGKMSYTSPGRQMSQQNLTKQTGLSKNASSIPRSES 2396
                  S  P+      + ++    GKM+     +Q  Q     Q   S + SS    + 
Sbjct: 446  EKRESPSPAPKPRKVELSESEEDKGGKMAAADSVQQRRQYRRQNQQSSSDSGSSSSSEDE 505

Query: 2397 ASKGLNQMNNGNGANKKVELSRMSSTKSSGSESD--------RSERPVLVRQSTFIKEAP 2448
              K  +  N   G  ++   SR +S      + +        RS  P   R+      AP
Sbjct: 506  RPKRSHVKNGEVGRRRRHSPSRSASPSPRKRQKETSPRGRRRRSPSPPPTRRRRSPSPAP 565

Query: 2449 SPTLRRKLEESASFESLSPSSRPASPTRSQAQTPV---LSPSLPDMSLSTHSSVQAGGWR 2505
             P  RR         + SP  R  SP+  +   P+    SPS P    +  +S      R
Sbjct: 566  PPRRRRTPTPPPRRRTPSPPPRRRSPSPRRYSPPIQRRYSPSPPPKRRT--ASPPPPPKR 623

Query: 2506 KLPPNLSPTIEYNDGRPAKRHDIARSHSESPSRLPINRSGT---------WKREHSKHSS 2556
            +  P+  P    +   P K+     +   SPS    +R G+            + +K  S
Sbjct: 624  RASPSPPPKRRVSHSPPPKQRSSPVTKRRSPSLSSKHRKGSSPSRSTREARSPQPNKRHS 683

Query: 2557 SLPRVSTWRRTGSSSSILSASSESSEK--AKSEDEKHVNSISGTKQSKENQVSAKGTWRK 2614
              PR    + + S   +   +S S ++  + S   + +  +S T + K+ + +A  + + 
Sbjct: 684  PSPRPRAPQTSSSPPPVRRGASSSPQRRQSPSPSTRPIRRVSRTPEPKKIKKAASPSPQS 743

Query: 2615 IKENEFSPTNSTSQTVSSGATNGAESKTLIYQMAPAVSKTEDVWVRIEDCPINNPRSGRS 2674
            ++    S + S S +    A       + +   +P+ + +  V V          +  +S
Sbjct: 744  VR--RVSSSRSVSGSPEPAAKKPPAPPSPVQSQSPSTNWSPAVPV----------KKAKS 791

Query: 2675 PTGNTPPVIDSVSEKANPNIKDSKDNQAKQN 2705
            PT +  P  +S  E      K  KD + K++
Sbjct: 792  PTPSPSPPRNSDQEGGGKKKKKKKDKKHKKD 822



 Score = 62.0 bits (149), Expect = 8e-09
 Identities = 148/705 (20%), Positives = 239/705 (33%), Gaps = 57/705 (8%)

Query: 2153 DQEEKPFTSNKGPRILKPGEKSTLETKKIESESKGIKGGKKVYKSLITGKVRSNSEISGQ 2212
            D+EEK  +  K  R   P  + +         S   +  K+ +      + +S S     
Sbjct: 155  DKEEKESSREKRERSRSPRRRKSRSPSPRRRSSPVRRERKRSHSRSPRHRTKSRSPSPAP 214

Query: 2213 MKQPLQANMPSISRGRTMIHIPGVRNSSSSTSPVSKKGPPLKTPASKSPSEGQTATTSPR 2272
             K+     +P  S     +  P V+ ++S TS + K   P   P  K PS  + +     
Sbjct: 215  EKKEKTPELPEPS---VKVKEPSVQEATS-TSDILKVPKPEPIPEPKEPSPEKNSKKEKE 270

Query: 2273 GAKPSVKSELSPVARQTSQIGGSSKAPSRSGSRDSTPSR-----PAQQPLSRPIQSPGRN 2327
              K   +S     +R  S+    S++PS +  R    SR     P ++P  R   SP R 
Sbjct: 271  KEKTRPRSR----SRSKSRSRTRSRSPSHTRPRRRHRSRSRSYSPRRRPSPRRRPSPRRR 326

Query: 2328 SISPGRNGISPPNKLSQLP----RTSSPSTASTKSSGSGKMSYTSPGR--QMSQQNLTKQ 2381
            +  P R    P ++ S+ P    R SS S + + SS S   S + P +  + +     K 
Sbjct: 327  T-PPRRMPPPPRHRRSRSPVRRRRRSSASLSGSSSSSSSSRSRSPPKKPPKRTSSPPRKT 385

Query: 2382 TGLSKNASSIPRSESASKGLNQMNNGNGANKKVELSRMSSTKSSGSESDRSERPVLVRQS 2441
              LS +AS   R    S           +    + +R   ++ S S   R+   V   + 
Sbjct: 386  RRLSPSASPPRRRHRPSPPATPPPKTRHSPTPQQSNRTRKSRVSVSPG-RTSGKVTKHKG 444

Query: 2442 TFIKEAPSPTLR-RKLEESASFESLSPSSRPASPTRSQAQTPVLSPSLPDMSLSTHSSVQ 2500
            T  +E+PSP  + RK+E S S E        A   + + Q    +      S S+ SS  
Sbjct: 445  TEKRESPSPAPKPRKVELSESEEDKGGKMAAADSVQQRRQYRRQNQQSSSDSGSSSSSED 504

Query: 2501 AGGWRKLPPNLSPTIEYNDGRPAKRHDIARSHSESPSRLPINRSGTWKREHS-------- 2552
                    P  S       GR  +RH  +RS S SP +     S   +R  S        
Sbjct: 505  E------RPKRSHVKNGEVGR-RRRHSPSRSASPSPRKRQKETSPRGRRRRSPSPPPTRR 557

Query: 2553 KHSSSLPRVSTWRRTGSSSSILSASSESSEKAKSEDEKHVNSISGTKQSKENQVSAKGTW 2612
            + S S       RRT +        S    +      ++   I               + 
Sbjct: 558  RRSPSPAPPPRRRRTPTPPPRRRTPSPPPRRRSPSPRRYSPPIQRRYSPSPPPKRRTASP 617

Query: 2613 RKIKENEFSPTNSTSQTVSSGATNGAESKTLIYQMAPAVSKTEDVWVRIEDCPINNPRSG 2672
                +   SP+    + VS        S  +  + +P++S       R    P  + R  
Sbjct: 618  PPPPKRRASPSPPPKRRVSHSPPPKQRSSPVTKRRSPSLSSKH----RKGSSPSRSTREA 673

Query: 2673 RSPTGNTPPVIDSVSEKANPNIKDSKDNQAKQNVGNGSVPMRTVGLENRLNSFIQVDAPD 2732
            RSP  N        S    P    +  +      G  S P R            +V    
Sbjct: 674  RSPQPN-----KRHSPSPRPRAPQTSSSPPPVRRGASSSPQRRQSPSPSTRPIRRVSRTP 728

Query: 2733 QKGTEIKPGQNNPVPVSETNESSIVERTPFSSSSSSKHSSPSGTVAARVTPFNYNPSPRK 2792
            +     K    +P  V   + S  V  +P    ++ K  +P   V ++    N++P+   
Sbjct: 729  EPKKIKKAASPSPQSVRRVSSSRSVSGSP--EPAAKKPPAPPSPVQSQSPSTNWSPAVPV 786

Query: 2793 SSADSTSARPSQIPTPVNNNT-----KKRDSKTDSTESSGTQSPK 2832
              A S    P+  P+P  N+      KK+  K D       +  K
Sbjct: 787  KKAKS----PTPSPSPPRNSDQEGGGKKKKKKKDKKHKKDKKHKK 827



 Score = 46.6 bits (109), Expect = 4e-04
 Identities = 60/251 (23%), Positives = 91/251 (36%), Gaps = 24/251 (9%)

Query: 2234 PGVRNSSSSTSPVSKKG--PPLKTPASKSPSEGQTATTSPRGAKPSVKSELSPVARQTSQ 2291
            P  +  S S S   +KG  P   T  ++SP   +  + SPR   P   S   PV R    
Sbjct: 647  PVTKRRSPSLSSKHRKGSSPSRSTREARSPQPNKRHSPSPRPRAPQTSSSPPPVRR---- 702

Query: 2292 IGGSSKAPSRSGSRDSTPSRPAQQPLSRPIQSPGRNSISPGRNGISPPNKLSQLPRTSSP 2351
              G+S +P R  S    PS P+ +P+ R  ++P    I   +   SP  +   + R SS 
Sbjct: 703  --GASSSPQRRQS----PS-PSTRPIRRVSRTPEPKKI---KKAASPSPQ--SVRRVSSS 750

Query: 2352 STASTKSSGSGKMSYTSPGRQMSQQNLTKQTGL--SKNASSIPRSESASKGLNQMNNGNG 2409
             + S     + K     P    SQ   T  +     K A S   S S  +  +Q   G  
Sbjct: 751  RSVSGSPEPAAKKPPAPPSPVQSQSPSTNWSPAVPVKKAKSPTPSPSPPRNSDQEGGGKK 810

Query: 2410 ANKKVELSRMSSTKSSGSESDRSERPVLVRQSTFIKEAPSPTLRRKLEESASFESLSPSS 2469
              KK +       K    +  + E+ V    +  +  A        L +    E    + 
Sbjct: 811  KKKKKDKKHKKDKKHKKHKKHKKEKAVAAAAAAAVTPAAIAAATTTLAQ----EEPVAAP 866

Query: 2470 RPASPTRSQAQ 2480
             P   T S+A+
Sbjct: 867  EPKKETESEAE 877



 Score = 38.5 bits (88), Expect = 0.096
 Identities = 99/477 (20%), Positives = 157/477 (32%), Gaps = 65/477 (13%)

Query: 1207 KTEHMSSSSENTSTPSSNAKRQNQLHPSSAQSRSGQPQKAATCKVSSINQETIQTYCVED 1266
            K +      +     SS  KR+    P   +SRS  P++    + S + +E  +++    
Sbjct: 146  KQDEDKDKRDKEEKESSREKRERSRSPRRRKSRSPSPRR----RSSPVRRERKRSHSRSP 201

Query: 1267 TPICFSRCSS-----------LSSLSSAEDEIGCNQTTQEADSANTLQIAEIKEKIGTRS 1315
                 SR  S           L   S    E    + T  +D     +   I E      
Sbjct: 202  RHRTKSRSPSPAPEKKEKTPELPEPSVKVKEPSVQEATSTSDILKVPKPEPIPEPKEPSP 261

Query: 1316 AEDPVSEVPAVSQHPRTKSSRLQGSSLSSESARHKAVEFSSGAKSPSKSGAQTPK----- 1370
             ++   E       PR++S     S   S S  H        ++S S S  + P      
Sbjct: 262  EKNSKKEKEKEKTRPRSRSRSKSRSRTRSRSPSHTRPRRRHRSRSRSYSPRRRPSPRRRP 321

Query: 1371 ------------SPPEHYVQETPLMFSRCTSVSSLDSFESRSIASSVQSEP--------C 1410
                         PP H    +P+   R +S +SL    S S +S  +S P         
Sbjct: 322  SPRRRTPPRRMPPPPRHRRSRSPVRRRRRSS-ASLSGSSSSSSSSRSRSPPKKPPKRTSS 380

Query: 1411 SGMVSGIISPSDLPDSPGQTMPPSRSKTPPPPPQ---TAQTKREVPKNKAPTAEKRESGP 1467
                +  +SPS  P  P +   PS   TPPP  +   T Q      K++   +  R SG 
Sbjct: 381  PPRKTRRLSPSASP--PRRRHRPSPPATPPPKTRHSPTPQQSNRTRKSRVSVSPGRTSG- 437

Query: 1468 KQAAVNAAVQRVQVLPDADTLLHFATESTPDGFSCSSSLSALSLDEPFIQKDVELRIMPP 1527
            K        +R    P         +ES  D     ++  +       +Q+  + R    
Sbjct: 438  KVTKHKGTEKRESPSPAPKPRKVELSESEEDKGGKMAAADS-------VQQRRQYRRQNQ 490

Query: 1528 VQENDNG--NETESEQPKESNENQEKEAEKTIDSEKDLLDDS-----DDDDIEILEECII 1580
               +D+G  + +E E+PK S+    +   +   S       S      +           
Sbjct: 491  QSSSDSGSSSSSEDERPKRSHVKNGEVGRRRRHSPSRSASPSPRKRQKETSPRGRRRRSP 550

Query: 1581 SAMPTKSSRK---AKKPAQTASKLPPPVARKPSQLPVYKLLPSQNRLQPQKHVSFTP 1634
            S  PT+  R    A  P +  +  PPP  R PS  P  +  PS  R  P     ++P
Sbjct: 551  SPPPTRRRRSPSPAPPPRRRRTPTPPPRRRTPSP-PPRRRSPSPRRYSPPIQRRYSP 606



 Score = 32.3 bits (72), Expect = 6.9
 Identities = 42/202 (20%), Positives = 73/202 (36%), Gaps = 17/202 (8%)

Query: 1319 PVSEVPAVSQHPRTKSSRLQGSSLSSESARHKAVEFSSGAKSPSKSGAQTPKSPPEHYVQ 1378
            P    P+     R+ S R     +    +     +  + +  P      +P  PP+  V 
Sbjct: 577  PRRRTPSPPPRRRSPSPRRYSPPIQRRYSPSPPPKRRTASPPPPPKRRASPSPPPKRRVS 636

Query: 1379 ETPLMFSRCTSVSSLDSFESRSIASSVQSEPCSGMVSGIISPSDLPDSPGQTMPPSRSKT 1438
             +P    R + V+   S        S+ S+   G      SPS       ++  P++  +
Sbjct: 637  HSPPPKQRSSPVTKRRS-------PSLSSKHRKGS-----SPSR-STREARSPQPNKRHS 683

Query: 1439 PPPPPQTAQTKREVP--KNKAPTAEKRESGPKQAAVNAAVQRVQVLPDADTLLHFATEST 1496
            P P P+  QT    P  +  A ++ +R   P  +     ++RV   P+   +   A+ S 
Sbjct: 684  PSPRPRAPQTSSSPPPVRRGASSSPQRRQSPSPS--TRPIRRVSRTPEPKKIKKAASPSP 741

Query: 1497 PDGFSCSSSLSALSLDEPFIQK 1518
                  SSS S     EP  +K
Sbjct: 742  QSVRRVSSSRSVSGSPEPAAKK 763


>gi|224548936 hypothetical protein LOC100170229 [Homo sapiens]
          Length = 715

 Score = 71.2 bits (173), Expect = 1e-11
 Identities = 164/762 (21%), Positives = 273/762 (35%), Gaps = 95/762 (12%)

Query: 2113 SSLHQAAAAACLSRQASSDSDSILSLKSGISLGSPFHLTPDQEEKPFTSNKGPRILKPGE 2172
            SS    + A   S   ++D     SLKS  S      L P    KP TS     ++ P  
Sbjct: 7    SSKPSMSLAPSGSSMPTADPKPPASLKSTKSATPNRSLVPT---KPATSRNS--VMSPSS 61

Query: 2173 -KSTLETKKIESESKGIKGGKKVYKSLITGKVRSNSEISGQMKQPLQANMPSI------- 2224
             KST  T      +K     +   +S +  K R+ S +S   +    +    +       
Sbjct: 62   SKSTKSTS-----TKRAPSNRPSSRSRVRSKARTPSRVSTDTRTSKASKASDVRCHQRRG 116

Query: 2225 --SRGRTMIHIPGVRNSSSSTSPVSKKGPPLKTPASKSPSEGQTATTSPRGAKPSVKSEL 2282
              SRGRT    PG R S SS     K+ P      S++ + G+  T    GA+P + S +
Sbjct: 117  THSRGRT----PGRRGSRSS-----KRSP------SRASTPGRIRT---HGARPGMASRV 158

Query: 2283 SPVARQTSQIGGSSKAPSRSGSRDSTPSRPAQQPLSRPIQSP------GRNS---ISPGR 2333
                 Q     G S    R+ +R+ + S+P    LS+    P      GR+S   ++P  
Sbjct: 159  RTPTSQQKGSRGKSYGRPRTSNRERSDSQPRN--LSKKSYRPPGGSGIGRSSELAVTPST 216

Query: 2334 NGISPPNKLSQLPRTSSPSTASTKSSGS-GKMSYTSPGRQMSQQNLTKQTGLSKNASSIP 2392
                 P  +    ++ +PS +S++   S G+M   S  +  S   ++ +      AS+  
Sbjct: 217  AKCQTPTGIPSKEKSDNPSPSSSRKVKSYGQMIIPSREKSYSPTEMSSRVKSYNQASTRS 276

Query: 2393 RSESASKGLNQMNNGNGANKKVELS-RMSSTKSSGSESDRSERPVLVRQSTFIKEAPSPT 2451
            R +S S+  +   + +G+ K+     R  S K + S +    R  ++ Q           
Sbjct: 277  RPQSHSQSRSPRRSRSGSQKRTHSRVRSHSWKRNHSRARSRTRKGILSQMG--------- 327

Query: 2452 LRRKLEESASFESLSPSSRPASPTRSQAQTPVLSPSLPDMSLSTHSSVQAGGWRKLPPNL 2511
               +  +S S       ++  +P R ++     +PS       + SS +    R      
Sbjct: 328  ---RHSQSRSHSKGKSQNQSRTPRRGRSHNWSRNPSKERSHSHSRSSSKERDHRGSSSPR 384

Query: 2512 SPTIEYNDGRPAKRHDIARSHSESPSRLPINRSGTWKREHSKHSSSLPRVSTWRRTGSSS 2571
              +     G P K+ D +RS S + +R        +K      S S  +    R    S 
Sbjct: 385  KESGRSQSGSPNKQRDHSRSRSPNKARDRSRSRSPYKARDRSRSRSPNKA---RDCSRSR 441

Query: 2572 SILSASSESSEKAKSEDEKHVNSISGTKQSKENQVSAKGTWRKIKENEFSPTNSTSQTVS 2631
            S   A   S  ++ ++   H  S S  K    ++  +       KE + S   S S+   
Sbjct: 442  SPYKARDRSRSRSPNKARDHSRSRSPNKARDRSRSRSPS-----KERDHSQLGSPSKERD 496

Query: 2632 SGATNGAESKTLIYQMAPAVSKTEDVWVRIEDCPINNPRSGRSPTGNTPPVIDSVSEKAN 2691
               +  + SK    + + + SK  D             R  RSP         S S    
Sbjct: 497  HRRSR-SPSKERQCRQSRSSSKERDHRRSRSPSKERQRRQSRSPNKERDRS-QSRSPSEE 554

Query: 2692 PNIKDSKDNQAKQNVGNGSVPMRTVGLENRLNSFIQVDAPDQKGTEIKPGQNNPVPVSET 2751
               + S+    +++      P +        +S  + D    +    + G + P   S+ 
Sbjct: 555  REHRQSRSPSKERDRRRWRSPSKERERRQSRSSSEERDHSRSRSPNKQSGYSRPRASSKE 614

Query: 2752 NESSIVERTPFS------SSSSSKHSSPSGTVA----------ARVTPFNYNPSPRKSSA 2795
               S   RTP        S +SSK S PS +             R +  + N +P K+S+
Sbjct: 615  KAHSR-SRTPSKEGNHSQSRTSSKESDPSQSTVPRSPDWKRSPTRTSSLSQNRTPSKTSS 673

Query: 2796 DSTSARPSQIPTPVNNNTKKRDSKTDSTESSGTQSPKRHSGS 2837
             S S  PS           + DS+ D+T S  T   +R S S
Sbjct: 674  HSPSTFPSG-----GQTLSQDDSQADATTSKATLPGERSSSS 710



 Score = 58.2 bits (139), Expect = 1e-07
 Identities = 107/427 (25%), Positives = 164/427 (38%), Gaps = 58/427 (13%)

Query: 2213 MKQPLQANMPSISRGRTMIHIPGVRNSSSSTSPVSKKGPPLKT-----PA---------S 2258
            M  P +++ PS+S   +   +P       ++   +K   P ++     PA         S
Sbjct: 1    MSSPKRSSKPSMSLAPSGSSMPTADPKPPASLKSTKSATPNRSLVPTKPATSRNSVMSPS 60

Query: 2259 KSPSEGQTATTSPRGAKPSVKSELSPVARQTSQIGGSSKAPSRSGSRDSTPSRPAQQPLS 2318
             S S   T+T      +PS +S +   AR  S++   ++    S + D       +    
Sbjct: 61   SSKSTKSTSTKRAPSNRPSSRSRVRSKARTPSRVSTDTRTSKASKASD------VRCHQR 114

Query: 2319 RPIQSPGRNSISPGRNGISPPNKLSQLPRTSSPSTASTKSSGSGKMSYTSPGRQMSQQNL 2378
            R   S GR   +PGR G S  +K S   R S+P    T  +  G  S         + + 
Sbjct: 115  RGTHSRGR---TPGRRG-SRSSKRSP-SRASTPGRIRTHGARPGMASRVRTPTSQQKGSR 169

Query: 2379 TKQTGLSKNASSIPRSESASKGLNQMN----NGNGANKKVELSRMSST------------ 2422
             K  G  +  S+  RS+S  + L++ +     G+G  +  EL+   ST            
Sbjct: 170  GKSYGRPR-TSNRERSDSQPRNLSKKSYRPPGGSGIGRSSELAVTPSTAKCQTPTGIPSK 228

Query: 2423 KSSGSESDRSERPVLVRQSTFI---KEAPSPTLRRKLEESASFESLSPSSRPASPTRSQA 2479
            + S + S  S R V       I   +++ SPT         S+   S  SRP S   SQ+
Sbjct: 229  EKSDNPSPSSSRKVKSYGQMIIPSREKSYSPT--EMSSRVKSYNQASTRSRPQS--HSQS 284

Query: 2480 QTPVLSPSLPDMSLSTHSSVQAGGWRKLPPNLSPTIEYNDGRPAKRHDIARSH----SES 2535
            ++P  S S       THS V++  W++                  RH  +RSH    S++
Sbjct: 285  RSPRRSRS--GSQKRTHSRVRSHSWKRNHSRARSRTRKGILSQMGRHSQSRSHSKGKSQN 342

Query: 2536 PSRLP-INRSGTWKREHSK-HSSSLPRVSTWRRT-GSSSSILSASSESSEKAKSEDEKHV 2592
             SR P   RS  W R  SK  S S  R S+  R    SSS    S  S   + ++   H 
Sbjct: 343  QSRTPRRGRSHNWSRNPSKERSHSHSRSSSKERDHRGSSSPRKESGRSQSGSPNKQRDHS 402

Query: 2593 NSISGTK 2599
             S S  K
Sbjct: 403  RSRSPNK 409



 Score = 53.9 bits (128), Expect = 2e-06
 Identities = 82/333 (24%), Positives = 131/333 (39%), Gaps = 47/333 (14%)

Query: 2204 RSNSEISGQMKQPLQANMPSISRGRTMIHIP-GVRNSSSSTSP-----VSKKGPPLKT-- 2255
            RS S    + +   ++  P+ +R R+    P   R+ S S SP      S+   P K   
Sbjct: 389  RSQSGSPNKQRDHSRSRSPNKARDRSRSRSPYKARDRSRSRSPNKARDCSRSRSPYKARD 448

Query: 2256 -PASKSPSEGQ--TATTSPRGAKPSVKSELSPVARQTSQIGGSSKAPSRSGSRDSTPSRP 2312
               S+SP++ +  + + SP  A+   +S      R  SQ+G  SK      SR  +  R 
Sbjct: 449  RSRSRSPNKARDHSRSRSPNKARDRSRSRSPSKERDHSQLGSPSKERDHRRSRSPSKERQ 508

Query: 2313 AQQPLSRPIQSPGRNSISPG----RNGISPPNKLSQLPRTSSPS------TASTKSSGSG 2362
             +Q  S   +   R S SP     R     PNK     ++ SPS       + + S    
Sbjct: 509  CRQSRSSSKERDHRRSRSPSKERQRRQSRSPNKERDRSQSRSPSEEREHRQSRSPSKERD 568

Query: 2363 KMSYTSPGRQMSQQNLTKQTGLSKNASSIPRSESASKGLNQMN-----NGNGANKKVELS 2417
            +  + SP ++  ++           +SS  R  S S+  N+ +       +   K    S
Sbjct: 569  RRRWRSPSKERERR--------QSRSSSEERDHSRSRSPNKQSGYSRPRASSKEKAHSRS 620

Query: 2418 RMSSTKSSGSESDRSERPVLVRQSTFIKEAP----SPTLRRKLEES---ASFESLSPSSR 2470
            R  S + + S+S  S +     QST +  +P    SPT    L ++   +   S SPS+ 
Sbjct: 621  RTPSKEGNHSQSRTSSKESDPSQST-VPRSPDWKRSPTRTSSLSQNRTPSKTSSHSPSTF 679

Query: 2471 PA-----SPTRSQAQTPVLSPSLPDMSLSTHSS 2498
            P+     S   SQA       +LP    S+ SS
Sbjct: 680  PSGGQTLSQDDSQADATTSKATLPGERSSSSSS 712



 Score = 41.2 bits (95), Expect = 0.015
 Identities = 118/684 (17%), Positives = 257/684 (37%), Gaps = 66/684 (9%)

Query: 722  SAAALRNLMANRPAKYKDANIMSPGSSLPSLHVRKQKA------LEAELDAQHLSETFDN 775
            SA   R+L+  +PA  +++ +MSP SS  +     ++A        + + ++  + +  +
Sbjct: 37   SATPNRSLVPTKPATSRNS-VMSPSSSKSTKSTSTKRAPSNRPSSRSRVRSKARTPSRVS 95

Query: 776  IDNLSPKASHRSKQRHKQSLYGDYVFDTNRHDDNRSDNFNTGNMTV--------LSPYLN 827
             D  + KAS  S  R  Q         T     +RS   +    +           P + 
Sbjct: 96   TDTRTSKASKASDVRCHQRRGTHSRGRTPGRRGSRSSKRSPSRASTPGRIRTHGARPGMA 155

Query: 828  TTVLPSSSSSRGSLDSS-----RSEKDRSLERERGIGLGNYHP-ATENPGTSSKRGLQIS 881
            + V   +S  +GS   S      S ++RS  + R +   +Y P      G SS+  +  S
Sbjct: 156  SRVRTPTSQQKGSRGKSYGRPRTSNRERSDSQPRNLSKKSYRPPGGSGIGRSSELAVTPS 215

Query: 882  TTAAQI-----AKVMEEVSAIHTSQEDRSSG-----STTELHCVTDERNALRRSSAAHTH 931
            T   Q      +K   +  +  +S++ +S G     S  + +  T+  + ++  + A T 
Sbjct: 216  TAKCQTPTGIPSKEKSDNPSPSSSRKVKSYGQMIIPSREKSYSPTEMSSRVKSYNQASTR 275

Query: 932  SNTYNFTKSENSNRTCSMPYAKLEYKRSSNDSLNSVSSSDGYGKRGQMKPSIESYSEDDE 991
            S   + ++S +  R+ S    +   +  S+    + S +    ++G     +       +
Sbjct: 276  SRPQSHSQSRSPRRSRSGSQKRTHSRVRSHSWKRNHSRARSRTRKG----ILSQMGRHSQ 331

Query: 992  SKFCSYGQYPADLAHKIHSANHMDDNDGELDTPINYSLKYSDEQLNSGRQSPSQNERWAR 1051
            S+  S G+            +H    +   +   ++S   S E+ + G  SP +    ++
Sbjct: 332  SRSHSKGKSQNQSRTPRRGRSHNWSRNPSKERSHSHSRSSSKERDHRGSSSPRKESGRSQ 391

Query: 1052 P--KHIIEDEIKQSEQRQSRNQSTTYPVYTESTDDKHLKFQPHFGQQ--ECVSPYRSRGA 1107
                +   D  +     ++R++S +   Y     D+     P+  +      SPY++R  
Sbjct: 392  SGSPNKQRDHSRSRSPNKARDRSRSRSPY--KARDRSRSRSPNKARDCSRSRSPYKARDR 449

Query: 1108 NGSETNRVGSNHGINQNVSQSLCQEDDYEDDKPTNYSERYSEEEQHEEEERPTNYSIKYN 1167
            + S +     +H  +++ +++  +       K  ++S+  S  ++ +     +    +  
Sbjct: 450  SRSRSPNKARDHSRSRSPNKARDRSRSRSPSKERDHSQLGSPSKERDHRRSRSPSKERQC 509

Query: 1168 EEKRHVDQPIDYSLKYATDIPSSQKQSFSFSKSSSGQSSKTEHMSSSSENTSTPSSNAKR 1227
             + R   +  D+    +      ++QS S +K      S++         + +PS    R
Sbjct: 510  RQSRSSSKERDHRRSRSPSKERQRRQSRSPNKERDRSQSRSPSEEREHRQSRSPSKERDR 569

Query: 1228 QNQLHPSS----AQSRSGQPQKAATCKVSSINQETIQTYCVEDTPICFSRCSSLSSLSSA 1283
            +    PS      QSRS   ++  +   S   Q              +SR       +S+
Sbjct: 570  RRWRSPSKERERRQSRSSSEERDHSRSRSPNKQSG------------YSR-----PRASS 612

Query: 1284 EDEIGCNQTTQEADSANTLQIAEIKEKIGTRSAEDPVSEVPAVSQHPRTKSSRLQGSSLS 1343
            +++      T   +  ++      KE   ++S    V   P   + P T++S L  +   
Sbjct: 613  KEKAHSRSRTPSKEGNHSQSRTSSKESDPSQST---VPRSPDWKRSP-TRTSSLSQNRTP 668

Query: 1344 SESARHKAVEFSSGAKSPSKSGAQ 1367
            S+++ H    F SG ++ S+  +Q
Sbjct: 669  SKTSSHSPSTFPSGGQTLSQDDSQ 692


>gi|161016767 mucin 21 [Homo sapiens]
          Length = 566

 Score = 70.9 bits (172), Expect = 2e-11
 Identities = 97/421 (23%), Positives = 165/421 (39%), Gaps = 35/421 (8%)

Query: 2224 ISRGRTMIHIPGVRNSSSSTSPVSKKGPPLKTPASKSPSEGQTATTSPRGAKPSVKSELS 2283
            IS G +     G   +SS  S  +  G  + +      +  +  TTS  G   +  SE S
Sbjct: 38   ISSGASTATNSGSSVTSSGVSTATISGSSVTSNGVSIVTNSEFHTTSS-GISTATNSEFS 96

Query: 2284 PVARQTSQIGGSSKAPSRSGSRDSTPSRPAQQPLSRPIQSPGRNSISPGRNGISPPNKLS 2343
             V+   S    S  + + SG+  +T S  +  P S    +   +S +      +  N  S
Sbjct: 97   TVSSGISIATNSESSTTSSGASTATNSE-SSTPSSGASTATNSDSSTTSSGASTATN--S 153

Query: 2344 QLPRTSSPSTASTKSSGSGKMSYTSPGRQMSQQNLTKQTGLSKNASSIPRSESASKGLNQ 2403
                TSS ++ +T S  S   S  S         ++ +   + N+ S   S  AS   N 
Sbjct: 154  DSSTTSSEASTATNSESSTTSSGASTATNSESSTVSSRASTATNSESSTTSSGASTATNS 213

Query: 2404 MNN--GNGANKKVELSRMSSTKSSGSESDRSERPVLVRQSTFIKEAPSPTLRRKLEESAS 2461
             +    NGA      S  S+T S  S +  SE       +     + S T       + +
Sbjct: 214  ESRTTSNGAGTATN-SESSTTSSGASTATNSESSTPSSGAGTATNSESSTTSSGAGTATN 272

Query: 2462 FESLSPSSRPASPTRSQAQTPVLSPSLPDMSLSTHSSVQAGGWRKLPPNLSPTIEYNDGR 2521
             ES + SS  ++ T S++ TP    S  + + ++ SS  + G        + T   +D  
Sbjct: 273  SESSTVSSGISTVTNSESSTP---SSGANTATNSESSTTSSG--------ANTATNSDSS 321

Query: 2522 PAKRHDIARSHSESPSRLPINRSGTWKREHSKHSSSLPRVSTWRRTGSSSSILSASSESS 2581
                     ++SES +      SG     +S+ S++    ST   +GSS++     S  +
Sbjct: 322  TTSSGASTATNSESST----TSSGASTATNSESSTTSSGASTATNSGSSTT-----SSGT 372

Query: 2582 EKAKSEDEKHVNSISGTKQSKENQVSAKGTWRKIKENEFSPTNSTSQTVSSGATNGAESK 2641
              A + +   V+S + T  + E+  ++ G          + TNS S TVSSGA+    S+
Sbjct: 373  STATNSESSTVSSGASTATTSESSTTSSGA--------STATNSESSTVSSGASTATNSE 424

Query: 2642 T 2642
            +
Sbjct: 425  S 425



 Score = 64.3 bits (155), Expect = 2e-09
 Identities = 90/414 (21%), Positives = 153/414 (36%), Gaps = 34/414 (8%)

Query: 2230 MIHIPGVRNSSSSTSPVSKKGPPLKTPASKSPSEGQTATTSPRGAKPSVKSELSPVARQT 2289
            ++H+    NS+ +++  +     + + AS + + G + T+S  G   +  S  S  +   
Sbjct: 15   LLHLEAATNSNETSTSANTGSSVISSGASTATNSGSSVTSS--GVSTATISGSSVTSNGV 72

Query: 2290 SQIGGSSKAPSRSGSRDSTPSRPAQQPLSRPIQSPGRNSISPGRNGISPPNKLSQLPRTS 2349
            S +  S    + SG   +T S                   S   +GIS     S+   TS
Sbjct: 73   SIVTNSEFHTTSSGISTATNSE-----------------FSTVSSGISIATN-SESSTTS 114

Query: 2350 SPSTASTKSSGSGKMSYTSPGRQMSQQNLTKQTGLSKNASSIPRSESASKGLNQMNNGNG 2409
            S ++ +T S  S   S  S          +     + N+ S   S  AS   N  ++   
Sbjct: 115  SGASTATNSESSTPSSGASTATNSDSSTTSSGASTATNSDSSTTSSEASTATNSESSTTS 174

Query: 2410 ANKKVELSRMSSTKSS-GSESDRSERPVLVRQSTFIKEAPSPTLRRKLEESASFESLSPS 2468
            +      +  SST SS  S +  SE       ++    + S T       + + ES + S
Sbjct: 175  SGASTATNSESSTVSSRASTATNSESSTTSSGASTATNSESRTTSNGAGTATNSESSTTS 234

Query: 2469 SRPASPTRSQAQTPVLSPSLPDMSLSTHSSVQAGGWRKLPPNLSPTIEYNDGRPAKRHDI 2528
            S  ++ T S++ TP         S S+ +S  AG         + T   +    +    +
Sbjct: 235  SGASTATNSESSTPSSGAGTATNSESSTTSSGAG---------TATNSESSTVSSGISTV 285

Query: 2529 ARSHSESPSRLPINRSGTWKREHSKHSSSLPRVSTWRRTGSSSSILSASSESSEKAKSED 2588
              S S +PS      +     E S  SS     +    + +SS   +A++  S    S  
Sbjct: 286  TNSESSTPSS---GANTATNSESSTTSSGANTATNSDSSTTSSGASTATNSESSTTSSGA 342

Query: 2589 EKHVNSISGTKQSKENQVSAKGTWRKIKENEFSPTNSTSQTVSSGATNGAESKT 2642
                NS S T  S  +  +  G+         + TNS S TVSSGA+    S++
Sbjct: 343  STATNSESSTTSSGASTATNSGS-STTSSGTSTATNSESSTVSSGASTATTSES 395



 Score = 60.5 bits (145), Expect = 2e-08
 Identities = 98/503 (19%), Positives = 181/503 (35%), Gaps = 76/503 (15%)

Query: 2348 TSSPSTASTKSSGSGKMSYTSPGRQMSQQNLTKQTGLSKNASSIPRSESASKGLNQMNNG 2407
            T+S  T+++ ++GS   S  S G   +  + +  T    + ++I  S   S G++ + N 
Sbjct: 22   TNSNETSTSANTGS---SVISSGASTATNSGSSVTSSGVSTATISGSSVTSNGVSIVTN- 77

Query: 2408 NGANKKVELSRMSSTKSSGSESDRSERPVLVRQSTFIKEAPSPTLRRKLEESASFESLSP 2467
                     S   +T S  S +  SE   +    +    + S T       + + ES +P
Sbjct: 78   ---------SEFHTTSSGISTATNSEFSTVSSGISIATNSESSTTSSGASTATNSESSTP 128

Query: 2468 SSRPASPTRSQAQTPVLSPSLPDMSLSTHSSVQAGGWRKLPPNLSPTIEYNDGRPAKRHD 2527
            SS  ++ T S + T     S    S S+ +S +A                          
Sbjct: 129  SSGASTATNSDSSTTSSGASTATNSDSSTTSSEAS------------------------- 163

Query: 2528 IARSHSESPSRLPINRSGTWKREHSKHSSSLPRVSTWRRTGSSSSILSASSESSEKAKSE 2587
               ++SES +      SG     +S+ S+   R ST     +++S  S +S  +  A + 
Sbjct: 164  -TATNSESST----TSSGASTATNSESSTVSSRAST-----ATNSESSTTSSGASTATNS 213

Query: 2588 DEKHVNSISGTKQSKENQVSAKGTWRKIKENEFSP-------TNSTSQTVSSGATNGAES 2640
            + +  ++ +GT  + E+  ++ G          +P       TNS S T SSGA     S
Sbjct: 214  ESRTTSNGAGTATNSESSTTSSGASTATNSESSTPSSGAGTATNSESSTTSSGAGTATNS 273

Query: 2641 KTLIYQMAPAVSKTEDVWVRIEDCPINNPRSGRSPTGNTPPVIDSVSEKANPNIKDSKDN 2700
            ++         S        + +   + P SG +   N+     S       N   S  +
Sbjct: 274  ES---------STVSSGISTVTNSESSTPSSGANTATNSESSTTSSGANTATNSDSSTTS 324

Query: 2701 QAKQNVGNGSVPMRTVGLENRLNSFIQVDAPDQKGTEIKPGQNNPVPVSETNESSIVERT 2760
                   N      + G     NS     +    G        +    S T+ ++  E +
Sbjct: 325  SGASTATNSESSTTSSGASTATNS---ESSTTSSGASTATNSGSSTTSSGTSTATNSESS 381

Query: 2761 PFSSSSSSKHSSPSGTVAARVTPFNYNPSPRKSSADSTSARPSQIPTPVNNNTKKRDSKT 2820
              SS +S+  +S S T ++  +    + S   SS  ST+          N+ +    S  
Sbjct: 382  TVSSGASTATTSESSTTSSGASTATNSESSTVSSGASTAT---------NSESSTTSSGA 432

Query: 2821 DSTESSGTQSPKRHSGSYLVTSV 2843
            ++  +SG+      SG+  +T +
Sbjct: 433  NTATNSGSSVTSAGSGTAALTGM 455



 Score = 49.3 bits (116), Expect = 5e-05
 Identities = 76/348 (21%), Positives = 127/348 (36%), Gaps = 11/348 (3%)

Query: 1167 NEEKRHVDQPIDYSLKYATDIPSSQKQSFSFSKSSSGQSSKTEHMSSSSENTSTPSSNAK 1226
            N E   V   I  +    +   SS   + + S+SS+  S  +   +S S  TS+ +S A 
Sbjct: 92   NSEFSTVSSGISIATNSESSTTSSGASTATNSESSTPSSGASTATNSDSSTTSSGASTAT 151

Query: 1227 RQNQLHPSSAQSRSGQPQKAATCK-VSSINQETIQTYCVEDTPICFSRCSSLSSLSSAED 1285
              +    SS  S +   + + T    S+       T     +    S  S+ SS +S   
Sbjct: 152  NSDSSTTSSEASTATNSESSTTSSGASTATNSESSTVSSRASTATNSESSTTSSGASTAT 211

Query: 1286 EIGCNQTTQEADSANTLQIAEIKEKIGTRSAEDPVSEVPAVSQHPRTKSSRLQGSSLSSE 1345
                  T+  A +A   + +      G  +A +  S  P+      T S     SS +  
Sbjct: 212  NSESRTTSNGAGTATNSESSTTSS--GASTATNSESSTPSSGAGTATNSESSTTSSGAGT 269

Query: 1346 SARHKAVEFSSGAKSPSKSGAQTPKSPPEHYV-QETPLMFSRCTSVSSLDSFESRSIAS- 1403
            +   ++   SSG  + + S + TP S        E+    S   + ++ DS  + S AS 
Sbjct: 270  ATNSESSTVSSGISTVTNSESSTPSSGANTATNSESSTTSSGANTATNSDSSTTSSGAST 329

Query: 1404 ---SVQSEPCSGMVSGIISPSDLPDSPGQTMPPSRSKTPPPPPQTA-QTKREVPKNKAPT 1459
               S  S   SG  +   S S    S   T   S S T      TA  ++     + A T
Sbjct: 330  ATNSESSTTSSGASTATNSESSTTSSGASTATNSGSSTTSSGTSTATNSESSTVSSGAST 389

Query: 1460 AEKRESGPKQAAVNAAV--QRVQVLPDADTLLHFATESTPDGFSCSSS 1505
            A   ES    +  + A   +   V   A T  +  + +T  G + +++
Sbjct: 390  ATTSESSTTSSGASTATNSESSTVSSGASTATNSESSTTSSGANTATN 437



 Score = 41.6 bits (96), Expect = 0.011
 Identities = 82/382 (21%), Positives = 131/382 (34%), Gaps = 52/382 (13%)

Query: 2104 IQEGANSIVSSLHQAAAAACLSRQASSDSDSILSLKSGISLGSPFHLTPDQEEKPFTSNK 2163
            I    NS  S+    A+ A  S  ++  S +  +  S  S  S    T    +   TS+ 
Sbjct: 102  ISIATNSESSTTSSGASTATNSESSTPSSGASTATNSDSSTTSSGASTATNSDSSTTSS- 160

Query: 2164 GPRILKPGEKSTLETKKIESESKGIKGGKKVYKSLITGKVRS--NSEISGQMKQPLQANM 2221
                    E ST    +  + S G         S ++ +  +  NSE S        A+ 
Sbjct: 161  --------EASTATNSESSTTSSGASTATNSESSTVSSRASTATNSESSTTSSG---AST 209

Query: 2222 PSISRGRTMIHIPGVRNSSSSTSPVSKKGPPLKTPASKSPSEGQTAT-----TSPRGAKP 2276
             + S  RT  +  G   +S S++  S       + +S   S   TAT     T+  GA  
Sbjct: 210  ATNSESRTTSNGAGTATNSESSTTSSGASTATNSESSTPSSGAGTATNSESSTTSSGAGT 269

Query: 2277 SVKSELSPVARQTSQIGGSSKAPSRSGSRDSTPSRPAQQPLSRPIQSPGRNSISPGRNGI 2336
            +  SE S V+   S +  S  +   SG+  +T S  +    S    +   +  S   +G 
Sbjct: 270  ATNSESSTVSSGISTVTNSESSTPSSGANTATNSESSTT--SSGANTATNSDSSTTSSGA 327

Query: 2337 SPPNKLSQLPRTSSPSTASTKSSG---SGKMSYTSPGRQMSQQNLTKQTG-----LSKNA 2388
            S          +S  STA+   S    SG  + T+ G   +    +  T      +S  A
Sbjct: 328  STATNSESSTTSSGASTATNSESSTTSSGASTATNSGSSTTSSGTSTATNSESSTVSSGA 387

Query: 2389 SSIPRSESA-----------------SKGLNQMNNG------NGANKKVELSRMSSTKSS 2425
            S+   SES+                 S G +   N       +GAN         ++  S
Sbjct: 388  STATTSESSTTSSGASTATNSESSTVSSGASTATNSESSTTSSGANTATNSGSSVTSAGS 447

Query: 2426 GSESDRSERPVLVRQSTFIKEA 2447
            G+ +           ST + EA
Sbjct: 448  GTAALTGMHTTSHSASTAVSEA 469



 Score = 40.4 bits (93), Expect = 0.025
 Identities = 71/339 (20%), Positives = 121/339 (35%), Gaps = 16/339 (4%)

Query: 2109 NSIVSSLHQAAAAACLSRQASSDSDSILSLKSGISLGSPFHLTPDQEEKPFTSNKGPRIL 2168
            NS  S+    A+ A  S  +++ S++  +  S  S  S    T    E    S++     
Sbjct: 137  NSDSSTTSSGASTATNSDSSTTSSEASTATNSESSTTSSGASTATNSESSTVSSRASTAT 196

Query: 2169 KPGEKSTLE--TKKIESESKGIKGGKKVY---KSLITGKVRSNSEISGQMKQPLQANMPS 2223
                 +T    +    SES+    G       +S  T    S +  S        A   +
Sbjct: 197  NSESSTTSSGASTATNSESRTTSNGAGTATNSESSTTSSGASTATNSESSTPSSGAGTAT 256

Query: 2224 ISRGRTMIHIPGVRNSSSSTSPVSKKGPPLKTPASKSPSEGQTATTSPRGAKPSVKSELS 2283
             S   T     G   +S S S VS     +    S +PS G    T+   ++ S  S  +
Sbjct: 257  NSESSTTSSGAGTATNSES-STVSSGISTVTNSESSTPSSGANTATN---SESSTTSSGA 312

Query: 2284 PVARQTSQIGGSSKAPSRSGSRDSTPSRPAQQPLSRPIQSPGRNSISPGRNGISPPNKLS 2343
              A  +     SS A + + S  ST S  A    +    +    + +   +G S  +  +
Sbjct: 313  NTATNSDSSTTSSGASTATNSESSTTSSGASTATNSESSTTSSGASTATNSGSSTTSSGT 372

Query: 2344 QLPRTSSPSTASTKSSGSGKMSYTSPGRQMSQQNLTKQTGLSKNASSIPRSESA--SKGL 2401
                 S  ST S+ +S +     ++     S    ++ + +S  AS+   SES+  S G 
Sbjct: 373  STATNSESSTVSSGASTATTSESSTTSSGASTATNSESSTVSSGASTATNSESSTTSSGA 432

Query: 2402 NQMNNG-----NGANKKVELSRMSSTKSSGSESDRSERP 2435
            N   N      +  +    L+ M +T  S S +    +P
Sbjct: 433  NTATNSGSSVTSAGSGTAALTGMHTTSHSASTAVSEAKP 471



 Score = 36.2 bits (82), Expect = 0.47
 Identities = 56/274 (20%), Positives = 97/274 (35%), Gaps = 20/274 (7%)

Query: 1110 SETNRVGSNHGINQNVSQSLCQEDDYEDDKPTNYSERYSEEEQHEEEERPTNYSIKYNEE 1169
            S T   G++   N   S    +     + + +  S   S     E            N E
Sbjct: 170  SSTTSSGASTATNSESSTVSSRASTATNSESSTTSSGASTATNSESRTTSNGAGTATNSE 229

Query: 1170 KRHVDQPIDYSLKYATDIPSSQKQSFSFSKSS---SGQSSKTEHMSS---------SSEN 1217
                      +    +  PSS   + + S+SS   SG  + T   SS         ++  
Sbjct: 230  SSTTSSGASTATNSESSTPSSGAGTATNSESSTTSSGAGTATNSESSTVSSGISTVTNSE 289

Query: 1218 TSTPSSNAKRQNQLHPSSAQSRSGQPQKAATCKVSS-----INQETIQTYCVEDTPICFS 1272
            +STPSS A        S+  S +     + +   SS      N E+  T     T    S
Sbjct: 290  SSTPSSGANTATNSESSTTSSGANTATNSDSSTTSSGASTATNSESSTTSSGAST-ATNS 348

Query: 1273 RCSSLSSLSSAEDEIGCNQTTQEADSANTLQIAEIKEKIGTRSAEDPVSEVPAVSQHPRT 1332
              S+ SS +S     G + T+    +A   + + +     T +  +  +     S    +
Sbjct: 349  ESSTTSSGASTATNSGSSTTSSGTSTATNSESSTVSSGASTATTSESSTTSSGASTATNS 408

Query: 1333 KSSRLQGSSLSSESARHKAVEFSSGAKSPSKSGA 1366
            +SS +  SS +S +   ++   SSGA + + SG+
Sbjct: 409  ESSTV--SSGASTATNSESSTTSSGANTATNSGS 440


>gi|207113162 Treacher Collins-Franceschetti syndrome 1 isoform e
            [Homo sapiens]
          Length = 1451

 Score = 69.7 bits (169), Expect = 4e-11
 Identities = 292/1468 (19%), Positives = 485/1468 (33%), Gaps = 224/1468 (15%)

Query: 1131 QEDDYEDDKPTNYSERYSEEEQHEEEERPTNYSIKY-------NEEKRHVDQPIDYSLKY 1183
            +ED     K T  S+  S  E  EEEE     + K        N      D P     K 
Sbjct: 66   EEDAALQAKKTRVSDPISTSESSEEEEEAEAETAKATPRLASTNSSVLGADLPSSMKEKA 125

Query: 1184 ATDIPSSQKQSFSFSKSSSGQSSKTEHMSSSSENTSTPSSNAKRQNQLHPSSAQSRSGQP 1243
              +   + K   S    ++G++        S   ++ PS+N    ++     +    G  
Sbjct: 126  KAETEKAGKTGNSMPHPATGKTVANLLSGKSPRKSAEPSANTTLVSETEEEGSVPAFGAA 185

Query: 1244 QKAATCKVSSINQETIQTYCVEDTPICFSRCSSLSSLSSAEDEIGCNQTTQEADSANTLQ 1303
             K         +  +      EDT       SS S  +  E +        +A S +T +
Sbjct: 186  AKPGMVSAGQADSSS------EDT-------SSSSDETDVEGKPSVKPAQVKASSVSTKE 232

Query: 1304 IAEIKEKIGTRSAEDPVSEVPAVSQHPRTKSSRLQGSSLSSESARHKAVEFSSGAKS--- 1360
                K         D   +V   +  P  ++ + +  S SSE       E  +G +S   
Sbjct: 233  SPARKAAPAPGKVGDVTPQVKGGALPPAKRAKKPEEESESSEEGSESEEEAPAGTRSQVK 292

Query: 1361 ------------------PSKSGAQTPKSPPEHYVQET----PLMFSRCTSVSSLDSFES 1398
                              P K     P         +T    P   S  +S  S DS E 
Sbjct: 293  ASEKILQVRAASAPAKGTPGKGATPAPPGKAGAVASQTKAGKPEEDSESSSEESSDSEEE 352

Query: 1399 RSIASSVQSEPCSGMVSGIISPS----------DLPDSPGQTMP---------------- 1432
               A ++     SG  S + + S            P  PG+T P                
Sbjct: 353  TPAAKALLQAKASGKTSQVGAASAPAKESPRKGAAPAPPGKTGPAVAKAQAGKREEDSQS 412

Query: 1433 -PSRSKTPPPPPQTAQTKREVPKNKAPTAEKRESGPKQAA------VNAAVQRVQVLPDA 1485
                S +    P  A+   + P+ +A +A  +ES  K AA         A  +VQV    
Sbjct: 413  SSEESDSEEEAPAQAKPSGKAPQVRAASAPAKESPRKGAAPAPPRKTGPAAAQVQVGKQE 472

Query: 1486 DTLLHFATESTPDGFSCSSSLSALSLDE-------PFIQKDVELRIMP------PVQEND 1532
            +     + ES  D      +L+A++  +       P ++    + + P      PV    
Sbjct: 473  EDSRSSSEESDSD----REALAAMNAAQVKPLGKSPQVKPASTMGMGPLGKGAGPVPPGK 528

Query: 1533 NGNETESEQPKESNENQEKEAEKTIDSEKDLLDDSDDDDIEILEECIISAMPTKSSRKAK 1592
             G  T S Q  +  E+ E  +E++ DS    +  +     E     I+ A PT S   AK
Sbjct: 529  VGPATPSAQVGKWEEDSESSSEESSDSSDGEVPTAVAPAQEKSLGNILQAKPTSS--PAK 586

Query: 1593 KPAQTASKLPPPV-ARKPSQLPVYKLLPSQNRLQPQKHVSFTPGDDMPRVYCVEGTPINF 1651
             P Q A  +   V A KP          S +    +   + T     P +   +      
Sbjct: 587  GPPQKAGPVAVQVKAEKPMDNSESSEESSDSADSEEAPAAMTAAQAKPALKIPQTKACPK 646

Query: 1652 STATSLSDLTIESPPNELAAGEGVRGGAQSGEFEKRDTIPTEGRSTDEAQGGKTSSVTIP 1711
             T T+ S           A    VR G Q+    K  T  +   S+    GG       P
Sbjct: 647  KTNTTAS-----------AKVAPVRVGTQAP--RKAGTATSPAGSSPAVAGGTQR----P 689

Query: 1712 ELDDNKAEEGDILAECINSAMPKGKSHKPFRVKKIMDQVQQASASSSAPNKNQLDGKKKK 1771
              D + +EE D   E    A+  G++      K +   +Q  +A  S P K  L G+   
Sbjct: 690  AEDSSSSEESDSEEEKTGLAVTVGQA------KSVGKGLQVKAA--SVPVKGSL-GQGTA 740

Query: 1772 PTSPVKPIPQNTEYRTRVRKNADSKNNLNAERVFSDNKDSKKQNLKNNSKVFNDKLPNNE 1831
            P  P K  P  T+ +   +++++S          SD++++     +  + V   +   N 
Sbjct: 741  PVLPGKTGPTVTQVKAEKQEDSESSEE------ESDSEEAAASPAQVKTSVKKTQAKANP 794

Query: 1832 DRVRGSFA---FDSPHHYTPIEGTPYCFSRNDSLSSLDFDDDDVDLSREKAELRKAKENK 1888
               R   A     +P             S +     +    +   L+R  A +    +  
Sbjct: 795  AAARAPSAKGTISAPGKVVTAAAQAKQRSPSKVKPPVRNPQNSTVLARGPASVPSVGKAV 854

Query: 1889 ESEAKVTSHTELTSNQQSANKTQAIAKQPINRGQPKPILQKQSTFPQSSKDIPDRGAATD 1948
             + A+  +  E  S             + + + +P     +       +K+ P +GAA  
Sbjct: 855  ATAAQAQTGPEEDSGSSEEESDSEEEAETLAQVKPSGKTHQIRAALAPAKESPRKGAAPT 914

Query: 1949 E--KLQNFAIENTPVCFSHNSSLSSLSDIDQENNNKENEPIKETEPPDSQGEPSK-PQAS 2005
               K    A +      S +SS  S SD +        + IK   PP    +P++ P   
Sbjct: 915  PPGKTGPSAAQAGKQDDSGSSSEESDSDGEAPAAVTSAQVIK---PPLIFVDPNRSPAGP 971

Query: 2006 GYAPKSFHVEDTP--VCFSRNSSLSSLSIDSEDDLL--QECIS-----------SAMPK- 2049
               P       TP     S +++ SS S   ++D++   +C++           +A P+ 
Sbjct: 972  AATPAQAQAASTPRKARASESTARSSSSESEDEDVIPATQCLTPGIRTNVVTMPTAHPRI 1031

Query: 2050 KKKPSRLKGDNEKHSPRNMGGILGEDLTLDLKDIQRPDSEHGLSPDSENFDWKAIQEGAN 2109
              K S     + K S R   G   E     +      DS  G  P +         +G N
Sbjct: 1032 APKASMAGASSSKESSRISDGKKQEGPATQV------DSAVGTLPATSPQSTSVQAKGTN 1085

Query: 2110 SIVSSLHQAAAAACLSRQASSDSDSILSLKSGISLGSPFHLTPDQEEKPFTSNKGPRILK 2169
             +          A  + ++S DS+      S  S GS       Q  K   +  GP    
Sbjct: 1086 KLRKPKLPEVQQATKAPESSDDSED----SSDSSSGSEEDGEGPQGAKSAHTLVGP---T 1138

Query: 2170 PGEKSTL--ETKKIESESKGIKGGKKVYKSLIT-GKVRSNSEISGQMKQPLQANMPSISR 2226
            P    TL  ET    SE   +   + +    +T G   +NS+ S     P   + PS+S 
Sbjct: 1139 PSRTETLVEETAAESSEDDVVAPSQSLLSGYMTPGLTPANSQAS--KATPKLDSSPSVSS 1196

Query: 2227 GRTMIHIP-------------------GVRNSSSSTSPVS----KKG---PPLKTPASKS 2260
                   P                   G + ++S T+P      KKG   P   T A +S
Sbjct: 1197 TLAAKDDPDGKQEAKPQQAAGMLSPKTGGKEAASGTTPQKSRKPKKGAGNPQASTLALQS 1256

Query: 2261 PSE----GQTATTSPRGAKPSVKSELSPVARQ-TSQIGGSSKAPSRSGSRDSTPSRPAQQ 2315
                   GQ    +    + SV   L+ +  Q   ++  ++K  SR G           Q
Sbjct: 1257 NITQCLLGQPWPLNEAQVQASVVKVLTELLEQERKKVVDTTKESSRKGWESRKRKLSGDQ 1316

Query: 2316 PLSRPIQSPGRNSISPGRNGISPPNKLSQLPRTSSPSTASTKSSGSGKMSYTSPGRQMSQ 2375
            P +R  +S  +  +  G  G            + SP   ST S G  K       R  + 
Sbjct: 1317 PAARTPRSKKKKKLGAGEGG----------EASVSPEKTSTTSKGKAK-------RDKAS 1359

Query: 2376 QNLTKQTG---LSKNASSIPRSESASKGLNQMNNGNGANKKVELSRMSSTKSSGSESDRS 2432
             ++ ++ G   L    +     E   KG+  +  G+ +N K +  +  S K    +  + 
Sbjct: 1360 GDVKEKKGKGSLGSQGAKDEPEEELQKGMGTVEGGDQSNPKSKKEKKKSDKRKKDKEKKE 1419

Query: 2433 ERPVLVRQSTFIKEAPSPTLRRKLEESA 2460
            ++    + ST   E+PS   ++K +++A
Sbjct: 1420 KKKKAKKASTKDSESPSQKKKKKKKKTA 1447



 Score = 55.8 bits (133), Expect = 6e-07
 Identities = 191/1024 (18%), Positives = 346/1024 (33%), Gaps = 155/1024 (15%)

Query: 1877 EKAELRKAKENKESEAKVTSHTELTSNQQSANKTQAIAKQPINRGQPKPILQKQSTFPQS 1936
            E    RKA+E+   +AK T  ++  S  +S+ + +  A+    +  P+      S     
Sbjct: 58   ELGRKRKAEEDAALQAKKTRVSDPISTSESSEEEEE-AEAETAKATPRLASTNSSVL--- 113

Query: 1937 SKDIPDRGAATDEKLQNFAIENTPVCFSHNSSLSSLSDIDQENNNKENEPIKETEPPDSQ 1996
              D+P   ++  EK +    E      + NS     +     N      P K  EP  + 
Sbjct: 114  GADLP---SSMKEKAK---AETEKAGKTGNSMPHPATGKTVANLLSGKSPRKSAEPSANT 167

Query: 1997 GEPSKPQASGYAPKSFHVEDTP--VCFSRNSSLSSLSIDSEDDLLQECISSAMPKKKKPS 2054
               S+ +  G  P +F     P  V   +  S S  +  S D+   E   S  P + K S
Sbjct: 168  TLVSETEEEGSVP-AFGAAAKPGMVSAGQADSSSEDTSSSSDETDVEGKPSVKPAQVKAS 226

Query: 2055 RLKGDNEKHSPRNMG----GILGEDLTLDLKDIQRPDSEHGLSPDSENFDWKAIQEGANS 2110
             +   + K SP        G +G D+T  +K    P ++    P+ E+   ++ +EG+ S
Sbjct: 227  SV---STKESPARKAAPAPGKVG-DVTPQVKGGALPPAKRAKKPEEES---ESSEEGSES 279

Query: 2111 IVSSLHQAAAAACLSRQASSDSDSILSLKSGISLGSPFHLTPDQEEKPFTSNKGPRILKP 2170
                  + A A   S+  +S+    +   S  + G+P               KG     P
Sbjct: 280  -----EEEAPAGTRSQVKASEKILQVRAASAPAKGTP--------------GKGATPAPP 320

Query: 2171 GEKSTLETKKIESESKGIKGGKKVYKSLITGKVRSNSEISGQMKQPLQANMPSISRGRTM 2230
            G+        + S++K              GK   +SE S +     +   P+    + +
Sbjct: 321  GKAGA-----VASQTKA-------------GKPEEDSESSSEESSDSEEETPA---AKAL 359

Query: 2231 IHIPGVRNSSSSTSPVSKKGPPLKTPASKSPSEGQTATTSPRGAKPSVKSELSPVARQTS 2290
            +       +S  TS V     P K    K  +      T P  AK             + 
Sbjct: 360  LQA----KASGKTSQVGAASAPAKESPRKGAAPAPPGKTGPAVAKAQAGKREEDSQSSSE 415

Query: 2291 QIGGSSKAPSRSGSRDSTPS-RPAQQPLSRPIQSPGRNSISPGRNGISPPNKLSQLPRTS 2349
            +     +AP+++      P  R A  P     +SP + +         P     Q+ +  
Sbjct: 416  ESDSEEEAPAQAKPSGKAPQVRAASAPAK---ESPRKGAAPAPPRKTGPAAAQVQVGKQE 472

Query: 2350 SPSTASTKSSGS----------------GKMSYTSPGRQMSQQNLTKQTGLSKNASSIPR 2393
              S +S++ S S                GK     P   M    L K  G        P 
Sbjct: 473  EDSRSSSEESDSDREALAAMNAAQVKPLGKSPQVKPASTMGMGPLGKGAGPVPPGKVGPA 532

Query: 2394 SESASKGLNQMNNGNGANKKVELSRMSSTKSSGSESDRSERPVLVRQSTFIKEAPSP--- 2450
            + SA  G  + ++ + + +  + S      +     ++S   +L  + T       P   
Sbjct: 533  TPSAQVGKWEEDSESSSEESSDSSDGEVPTAVAPAQEKSLGNILQAKPTSSPAKGPPQKA 592

Query: 2451 -------TLRRKLEESASFESLSPSS----RPASPTRSQAQTPVLSPSLPDMSLSTHSSV 2499
                      + ++ S S E  S S+     PA+ T +QA+  +  P        T+++ 
Sbjct: 593  GPVAVQVKAEKPMDNSESSEESSDSADSEEAPAAMTAAQAKPALKIPQTKACPKKTNTTA 652

Query: 2500 QA--------------GGWRKLPPNLSPTIEYNDGRPAKRHDIARSHSESPSR------- 2538
             A               G    P   SP +     RPA   + + S  ES S        
Sbjct: 653  SAKVAPVRVGTQAPRKAGTATSPAGSSPAVAGGTQRPA---EDSSSSEESDSEEEKTGLA 709

Query: 2539 LPINRSGTWKREHSKHSSSLPRVSTWRRTGSSSSILSASSESSEKAKSEDEKHVNSISGT 2598
            + + ++ +  +     ++S+P V      G++  +   +  +  + K+E ++   S    
Sbjct: 710  VTVGQAKSVGKGLQVKAASVP-VKGSLGQGTAPVLPGKTGPTVTQVKAEKQEDSESSEEE 768

Query: 2599 KQSKENQVSAKGTWRKIKENEFSPTNSTSQTVSSGATNGAESKTL-----IYQMAPAVSK 2653
              S+E   S       +K+ +     + ++  S+  T  A  K +       Q +P+  K
Sbjct: 769  SDSEEAAASPAQVKTSVKKTQAKANPAAARAPSAKGTISAPGKVVTAAAQAKQRSPSKVK 828

Query: 2654 TEDVWVRIEDCPINNPRS----GRSPTGNTPPVIDSVSEKANPNIKDSKDNQAKQNVGNG 2709
                       P+ NP++     R P  + P V  +V+  A       +D+ + +   + 
Sbjct: 829  P----------PVRNPQNSTVLARGP-ASVPSVGKAVATAAQAQTGPEEDSGSSEEESDS 877

Query: 2710 SVPMRTVGLENRLNSFIQVDAPDQKGTEIKPGQNNPVPVSETNESSIVERTPFSSSSSSK 2769
                 T+          Q+ A      E       P P  +T  S+        S SSS+
Sbjct: 878  EEEAETLAQVKPSGKTHQIRAALAPAKESPRKGAAPTPPGKTGPSAAQAGKQDDSGSSSE 937

Query: 2770 HSSPSGTVAARVTPFN--------YNPSPRKSSADSTSARPSQIPTPVNNNTKKRDSKTD 2821
             S   G   A VT            +P+   +   +T A+     TP      +  +++ 
Sbjct: 938  ESDSDGEAPAAVTSAQVIKPPLIFVDPNRSPAGPAATPAQAQAASTPRKARASESTARSS 997

Query: 2822 STES 2825
            S+ES
Sbjct: 998  SSES 1001



 Score = 37.4 bits (85), Expect = 0.21
 Identities = 74/346 (21%), Positives = 118/346 (34%), Gaps = 61/346 (17%)

Query: 2540 PINRSGTWKREHSKHSSSLPRVSTWRRTGSSSSILSASSESS--EKAKSEDEKH------ 2591
            PI+ S + + E    + +    +T R   ++SS+L A   SS  EKAK+E EK       
Sbjct: 81   PISTSESSEEEEEAEAETAK--ATPRLASTNSSVLGADLPSSMKEKAKAETEKAGKTGNS 138

Query: 2592 ----------VNSISGTKQSKENQVSAKGTWRKIKENEFSPTN----------STSQTVS 2631
                       N +SG    K  + SA  T     E E S             S  Q  S
Sbjct: 139  MPHPATGKTVANLLSGKSPRKSAEPSANTTLVSETEEEGSVPAFGAAAKPGMVSAGQADS 198

Query: 2632 SGATNGAESKTLIYQMAPAV--SKTEDVWVRIEDCPINNPRSGRSPTGNTPPVIDSVSEK 2689
            S     + S     +  P+V  ++ +   V  ++ P           G+  P +   +  
Sbjct: 199  SSEDTSSSSDETDVEGKPSVKPAQVKASSVSTKESPARKAAPAPGKVGDVTPQVKGGALP 258

Query: 2690 ANPNIKDSKDNQAKQNVGNGSVPMRTVGLENRLNS---FIQVDA--------PDQKGTEI 2738
                 K  ++       G+ S      G  +++ +    +QV A        P +  T  
Sbjct: 259  PAKRAKKPEEESESSEEGSESEEEAPAGTRSQVKASEKILQVRAASAPAKGTPGKGATPA 318

Query: 2739 KPGQNNPVPVSETNESSIVERTPFSSSSSS---------------KHSSPSGTVAARVTP 2783
             PG+   V  S+T      E +  SS  SS               K S  +  V A   P
Sbjct: 319  PPGKAGAV-ASQTKAGKPEEDSESSSEESSDSEEETPAAKALLQAKASGKTSQVGAASAP 377

Query: 2784 FNYNPSPRKSSADSTSARPSQIPTPVNNNTKKRDSKTDSTESSGTQ 2829
                 SPRK +A +   +            ++ DS++ S ES   +
Sbjct: 378  AK--ESPRKGAAPAPPGKTGPAVAKAQAGKREEDSQSSSEESDSEE 421


>gi|28559039 mediator complex subunit 1 [Homo sapiens]
          Length = 1581

 Score = 68.6 bits (166), Expect = 9e-11
 Identities = 128/620 (20%), Positives = 218/620 (35%), Gaps = 112/620 (18%)

Query: 2227 GRTMIHIPGVRNSSSSTSPVSKKGPPLKTPASKSPSEGQTATTSPRGAKPSVKSELSPVA 2286
            G+ +     + + S S  P+   G   K    K   EG   + S     P + S+    +
Sbjct: 938  GKALAPADLMEHHSGSQGPLLTTGDLGKEKTQKRVKEGNGTSNSTLSG-PGLDSKPGKRS 996

Query: 2287 RQTSQIGGSSKAPSRSGSRDSTPSRPAQQPLSRPIQSPGRN--SISPGRNGIS--PPNKL 2342
            R  S  G S   P +    D+    P+    +RP   P     S SPG  G S  PP   
Sbjct: 997  RTPSNDGKSKDKPPKRKKADTEGKSPSHSSSNRPFTPPTSTGGSKSPGSAGRSQTPPGVA 1056

Query: 2343 SQ-LPRTSSPSTASTKSSG--SGKMSYTSPGRQMSQQNLTKQTGLSKNASSIPRSESASK 2399
            +  +P+ +      T   G  S    YTS G   S  + +  +  S ++SS     S S 
Sbjct: 1057 TPPIPKITIQIPKGTVMVGKPSSHSQYTSSGSVSSSGSKSHHSHSSSSSSSA----STSG 1112

Query: 2400 GLNQMNNGNGANKKVELSRMSSTKSSGSESDRSERPVLVRQSTFIKEAPSPTLRRKLEES 2459
             +    +   ++ K+  S  SS  SSGS   ++         +  K   SP  +  L   
Sbjct: 1113 KMKSSKSEGSSSSKLSSSMYSSQGSSGSSQSKNS------SQSGGKPGSSPITKHGLSSG 1166

Query: 2460 ASFESLSPSSRPASPTRSQAQTPVLSPSLPDMSLSTHSSVQAGGWRKLPPNLSPTIEYND 2519
            +S   + P  +P+S         +++PSL   ++S   S   GG  KL   + P      
Sbjct: 1167 SSSTKMKPQGKPSS---------LMNPSLSKPNISPSHSRPPGGSDKLASPMKPV----P 1213

Query: 2520 GRPAKRHDIARSHSESPSRLPINRSGTWKREHSKHSSSLPRVSTWRRTGSSSSILSASSE 2579
            G P            S ++ PI+                        +GS  S +S +S 
Sbjct: 1214 GTPPS----------SKAKSPIS------------------------SGSGGSHMSGTSS 1239

Query: 2580 SSEKAKSEDEKHVNSISGTKQSKENQVSAKGTWRKIKENEFSPTNSTSQTVSSGATNGAE 2639
            SS    S       S+S                      + +P +S S T SS + + + 
Sbjct: 1240 SSGMKSSSGLGSSGSLS----------------------QKTPPSSNSCTASSSSFSSSG 1277

Query: 2640 SKTLIYQMAPAVSKTEDVWVRIEDCPINNPRSGRSPTGNTPPVIDSVSEK-------ANP 2692
            S     Q     SK                  G+SP+ N  P + +V +K       + P
Sbjct: 1278 SSMSSSQNQHGSSK------------------GKSPSRNKKPSLTAVIDKLKHGVVTSGP 1319

Query: 2693 NIKDSKDNQAKQNVGNGSVPMRTVGLENRLNSFIQVDAPDQKGTEIKPGQNNPVPVSETN 2752
              +D  D Q   +  + S PM +    +      + +  D+  +++    ++     +T+
Sbjct: 1320 GGEDPLDGQMGVSTNSSSHPMSSKHNMSGGEFQGKREKSDKDKSKVSTSGSSVDSSKKTS 1379

Query: 2753 ESSIVERTPFSSSSSSKHSSPSGTVAARVTPFNYNPSPRKSSADSTSARPSQIPTPVNNN 2812
            ES  V  T  +    SKH   S ++ A+VT      S  +      ++  +     ++ +
Sbjct: 1380 ESKNVGSTGVAKIIISKHDGGSPSIKAKVTLQKPGESSGEGLRPQMASSKNYGSPLISGS 1439

Query: 2813 TKKRDSKTDSTESSGTQSPK 2832
            T K +  + S   S   +P+
Sbjct: 1440 TPKHERGSPSHSKSPAYTPQ 1459



 Score = 56.6 bits (135), Expect = 3e-07
 Identities = 141/651 (21%), Positives = 228/651 (35%), Gaps = 116/651 (17%)

Query: 2187 GIKGGKKVYKSLITGKVRSNSEISG---QMKQPLQANMPSISRGRTMIHIPGVRNS---- 2239
            G  G +K  K +  G   SNS +SG     K   ++  PS + G++    P  + +    
Sbjct: 961  GDLGKEKTQKRVKEGNGTSNSTLSGPGLDSKPGKRSRTPS-NDGKSKDKPPKRKKADTEG 1019

Query: 2240 -----SSSTSPVSKKGPPLKTPASKSPSEGQTATTSPRGAKPSVKSELSPVARQTSQIG- 2293
                 SSS  P +   PP  T  SKSP     + T P  A P +      + + T  +G 
Sbjct: 1020 KSPSHSSSNRPFT---PPTSTGGSKSPGSAGRSQTPPGVATPPIPKITIQIPKGTVMVGK 1076

Query: 2294 -------GSSKAPSRSGSR------DSTPSRPAQQPLSRPIQSPGRNS--------ISPG 2332
                    SS + S SGS+       S+ S  +     +  +S G +S         S G
Sbjct: 1077 PSSHSQYTSSGSVSSSGSKSHHSHSSSSSSSASTSGKMKSSKSEGSSSSKLSSSMYSSQG 1136

Query: 2333 RNGISPPNKLSQL--PRTSSPSTASTKSSGSGKMSYTSPGRQMSQQN--LTKQT------ 2382
             +G S     SQ      SSP T    SSGS        G+  S  N  L+K        
Sbjct: 1137 SSGSSQSKNSSQSGGKPGSSPITKHGLSSGSSSTKMKPQGKPSSLMNPSLSKPNISPSHS 1196

Query: 2383 ----GLSKNAS---SIPRSESASKGLNQMNNGNGANKKVELSRMSSTKSSGSESDRSERP 2435
                G  K AS    +P +  +SK  + +++G+G +     S  S  KSS          
Sbjct: 1197 RPPGGSDKLASPMKPVPGTPPSSKAKSPISSGSGGSHMSGTSSSSGMKSSSGLGSSGSLS 1256

Query: 2436 VLVRQSTFIKEAPSPTLRRKLEESASFESLSPSSRPASPTRSQAQTPVLSPSLPDMSLST 2495
                 S+    A S +        +S ++   SS+  SP+R+  + P L+  +  +    
Sbjct: 1257 QKTPPSSNSCTASSSSFSSSGSSMSSSQNQHGSSKGKSPSRN--KKPSLTAVIDKLK--- 1311

Query: 2496 HSSVQAGGWRKLPPNLSPTIEYNDGRPAKRHDIARSHSESPSRLPINRSGTWKREHSKHS 2555
            H  V +G   + P +    +  N    +  H ++  H+ S         G ++ +  K  
Sbjct: 1312 HGVVTSGPGGEDPLDGQMGVSTN----SSSHPMSSKHNMS--------GGEFQGKREKSD 1359

Query: 2556 SSLPRVSTWRRTGSSSSILSASSESSEKAKSEDEKHVNSISGTKQSKENQVSAKGTWRKI 2615
                +VST      S S + +S ++SE            I          + AK T +K 
Sbjct: 1360 KDKSKVST------SGSSVDSSKKTSESKNVGSTGVAKIIISKHDGGSPSIKAKVTLQKP 1413

Query: 2616 KENE---FSPTNSTSQTVSSGATNGAESKTLIYQMAPAVSKTEDVWVRIEDCPINNPRSG 2672
             E+      P  ++S+   S   +G+  K                          +P   
Sbjct: 1414 GESSGEGLRPQMASSKNYGSPLISGSTPKH----------------------ERGSPSHS 1451

Query: 2673 RSPTGNTPPVIDSVSEKANPNIKDSKDNQAKQNVGNGSVPMRTVGLENR----------- 2721
            +SP   TP  +DS SE  +   + S  N    + G   +P  +     +           
Sbjct: 1452 KSP-AYTPQNLDSESESGSSIAEKSYQNSPSSDDGIRPLPEYSTEKHKKHKKEKKKVKDK 1510

Query: 2722 -LNSFIQVDAPDQKGTEIKPGQNNPVPVSETNESSIVERTPFSSSSSSKHS 2771
              +     D   +K   IKP   +  P+S     S+   T  S+   S+ S
Sbjct: 1511 DRDRDRDKDRDKKKSHSIKPESWSKSPISSDQSLSMTSNTILSADRPSRLS 1561



 Score = 47.0 bits (110), Expect = 3e-04
 Identities = 61/219 (27%), Positives = 90/219 (41%), Gaps = 14/219 (6%)

Query: 1188 PSSQKQ-SFSFSKSSSGQSSKTEHMSSSSENTSTPSSNAKRQNQLHPSSAQSRSGQPQKA 1246
            PSS  Q + S S SSSG  S   H SSSS + ST  S   + ++   SS+   S     +
Sbjct: 1077 PSSHSQYTSSGSVSSSGSKSHHSHSSSSSSSAST--SGKMKSSKSEGSSSSKLSSSMYSS 1134

Query: 1247 ATCKVSSINQETIQTYCVE-DTPICFSRCSSLSSLSSAEDEIGCNQTTQEADSANTLQIA 1305
                 SS ++ + Q+      +PI     SS SS +  + +   +     + S   +  +
Sbjct: 1135 QGSSGSSQSKNSSQSGGKPGSSPITKHGLSSGSSSTKMKPQGKPSSLMNPSLSKPNISPS 1194

Query: 1306 EIKEKIGTRSAEDPVSEVPAVSQHPRTKSSRLQGSSLSSESARHKAVEFSSGAKSPSKSG 1365
              +   G+     P+  VP      + KS    GS  S  S        SSG KS S  G
Sbjct: 1195 HSRPPGGSDKLASPMKPVPGTPPSSKAKSPISSGSGGSHMS----GTSSSSGMKSSSGLG 1250

Query: 1366 AQTPKSPPEHYVQETPLMFSRCTSVSSLDSFESRSIASS 1404
            +    S      Q+TP   + CT+ SS  S    S++SS
Sbjct: 1251 SSGSLS------QKTPPSSNSCTASSSSFSSSGSSMSSS 1283



 Score = 39.3 bits (90), Expect = 0.056
 Identities = 117/590 (19%), Positives = 200/590 (33%), Gaps = 90/590 (15%)

Query: 2298 APSRSGSRDSTPSRPAQQP---LSRPIQSPGRNSISPGRNGISPP--NKLSQLPRTSSP- 2351
            APS+  +  +T  +P   P   + R ++    +SI P    I      + S+LP TS   
Sbjct: 741  APSQCSTPPTTYPQPVPHPQPSIQRMVRLSSSDSIGPDVTDILSDIAEEASKLPSTSDDC 800

Query: 2352 ---STASTKSSGSGKMSYTSPGRQMSQQN-----LTKQTGLSKNASSIPRSESASKGLNQ 2403
                T    SS SG    T     + Q N      T    L  +A+  P S+S +     
Sbjct: 801  PAIGTPLRDSSSSGHSQSTLFDSDVFQTNNNENPYTDPADLIADAAGSPSSDSPTNHFFH 860

Query: 2404 MNNGNGANKKVELSRMSSTKSSGSE--------SDRSERPVLVRQSTFIKEAP------- 2448
                +G +   +L    S    G E         D  +      Q+      P       
Sbjct: 861  ----DGVDFNPDLLNSQSQSGFGEEYFDESSQSGDNDDFKGFASQALNTLGVPMLGGDNG 916

Query: 2449 -SPTLRRKLEESASFESLSPSSRPASPT-----RSQAQTPVLSPSLPDMSLS-THSSVQA 2501
             +        ++  F  +S + +  +P       S +Q P+L+    D+    T   V+ 
Sbjct: 917  ETKFKGNNQADTVDFSIISVAGKALAPADLMEHHSGSQGPLLTTG--DLGKEKTQKRVKE 974

Query: 2502 GGWRKLPPNLSPTIEYNDGRPAKRHDIARSHSESPSRLPINRSGTWKREHSKHSSSLPRV 2561
            G          P +   D +P KR     +  +S  + P  +    + +   HSSS    
Sbjct: 975  GNGTSNSTLSGPGL---DSKPGKRSRTPSNDGKSKDKPPKRKKADTEGKSPSHSSSNRPF 1031

Query: 2562 STWRRTGSSSSILSASSESSEKA-------KSEDEKHVNSISGTKQSKENQVSAKGTWRK 2614
            +    TG S S  SA    +          K   +    ++   K S  +Q ++ G+   
Sbjct: 1032 TPPTSTGGSKSPGSAGRSQTPPGVATPPIPKITIQIPKGTVMVGKPSSHSQYTSSGSVSS 1091

Query: 2615 I-------KENEFSPTNSTSQTVSSGATNGAESKTLIYQMAPAVSKTEDVWVRIEDCPIN 2667
                      +  S + STS  + S  + G+ S  L   M  +   +     +      N
Sbjct: 1092 SGSKSHHSHSSSSSSSASTSGKMKSSKSEGSSSSKLSSSMYSSQGSSGSSQSK------N 1145

Query: 2668 NPRSGRSPTGNTPPVIDSVSEKANPNIKDSKDNQAKQNVGNGSVPMRTVGLENRLNSFIQ 2727
            + +SG  P G++P     +S                   G+ S  M+  G  + L +   
Sbjct: 1146 SSQSGGKP-GSSPITKHGLSS------------------GSSSTKMKPQGKPSSLMN--- 1183

Query: 2728 VDAPDQKGTEIKPGQNNPVPVSETNESSIVERTPFSSSSSSKHSSPSGTVAARVTPFNYN 2787
               P      I P  + P   S+   S +        SS +K    SG+  + ++  + +
Sbjct: 1184 ---PSLSKPNISPSHSRPPGGSDKLASPMKPVPGTPPSSKAKSPISSGSGGSHMSGTSSS 1240

Query: 2788 PSPRKSSADSTSARPSQIPTPVNNNTKKRDSKTDSTESSGTQSPKRHSGS 2837
               + SS   +S   SQ   P +N+     S   S+ SS + S  +H  S
Sbjct: 1241 SGMKSSSGLGSSGSLSQKTPPSSNSCTASSSSFSSSGSSMSSSQNQHGSS 1290



 Score = 33.1 bits (74), Expect = 4.0
 Identities = 92/398 (23%), Positives = 138/398 (34%), Gaps = 75/398 (18%)

Query: 1188 PSSQKQSFSFSKSSSGQSSKTEHMSSSSENTSTPSSNAKR-----QNQLHPSSAQSRSGQ 1242
            PS  K + S S S     S            + PSS AK          H S   S SG 
Sbjct: 1184 PSLSKPNISPSHSRPPGGSDKLASPMKPVPGTPPSSKAKSPISSGSGGSHMSGTSSSSGM 1243

Query: 1243 PQKAATCKVSSINQETIQTYCVEDTPICFSRCSSLSSLSSAEDEIGCNQ---TTQEADSA 1299
               +      S++Q+T  +     T    S  SS SS+SS++++ G ++    ++    +
Sbjct: 1244 KSSSGLGSSGSLSQKTPPS-SNSCTASSSSFSSSGSSMSSSQNQHGSSKGKSPSRNKKPS 1302

Query: 1300 NTLQIAEIKEKIGTRS--AEDPVSEVPAVSQHPRTKSSRLQGSSLSSESARHKAVEFSSG 1357
             T  I ++K  + T     EDP+     VS +          SS    S++H     S G
Sbjct: 1303 LTAVIDKLKHGVVTSGPGGEDPLDGQMGVSTN----------SSSHPMSSKHN---MSGG 1349

Query: 1358 AKSPSKSGAQTPKSPPEHYVQETPLMFSRCTSVSSLDSFESRSIASSVQSEPCSGMVSGI 1417
                 +  +   KS                TS SS+DS +  S + +V S   +G+   I
Sbjct: 1350 EFQGKREKSDKDKSKVS-------------TSGSSVDSSKKTSESKNVGS---TGVAKII 1393

Query: 1418 ISPSDLPDSPG-----QTMPPSRSKTPPPPPQTAQTKREVPKNKAPTAEKRESGPKQAAV 1472
            IS  D   SP          P  S      PQ A +K       + +  K E G    + 
Sbjct: 1394 ISKHD-GGSPSIKAKVTLQKPGESSGEGLRPQMASSKNYGSPLISGSTPKHERGSPSHSK 1452

Query: 1473 NAAVQRVQVLPDADTLLHFATESTPDGFSCSSSLSALSLDEPFIQKDVELRIMPPVQEND 1532
            + A                    TP     S S S  S+ E   Q             +D
Sbjct: 1453 SPAY-------------------TPQNLD-SESESGSSIAEKSYQNS---------PSSD 1483

Query: 1533 NGNETESEQPKESNENQEKEAEKTIDSEKDLLDDSDDD 1570
            +G     E   E ++  +KE +K  D ++D   D D D
Sbjct: 1484 DGIRPLPEYSTEKHKKHKKEKKKVKDKDRDRDRDKDRD 1521


>gi|5174573 myeloid/lymphoid or mixed-lineage leukemia trithorax
            homolog 2 [Homo sapiens]
          Length = 1210

 Score = 67.4 bits (163), Expect = 2e-10
 Identities = 178/848 (20%), Positives = 300/848 (35%), Gaps = 135/848 (15%)

Query: 1753 ASASSSAPNKNQLDG-KKKKPTSPVKPIPQNTEYRTRVRKNADSKNNLNAERVFSDNKDS 1811
            AS + SAP +          P  P+ PI  N +   R + ++    + N  + +   K  
Sbjct: 187  ASVTDSAPERELSPLISLPSPVPPLSPIHSNQQTLPRTQGSSKVHGSSNNSKGYCPAKSP 246

Query: 1812 KKQNLKNNSKVF-NDKLPNNEDRVRGSFAFDS-----------PHHYT-PIEGTPYCFSR 1858
            K   +K + K    D L         +F   S           P  Y  P++G     S 
Sbjct: 247  KDLAVKVHDKETPQDSLVAPAQPPSQTFPPPSLPSKSVAMQQKPTAYVRPMDGQDQAPSE 306

Query: 1859 NDSLSSLDFDDDDVDLSREKAELRKAKENKESEAKVTSHTELTSNQQSANKTQAIAKQPI 1918
            +  L  L   +D    + EK +L+   + K ++ K+ S +   +     +  + I K+  
Sbjct: 307  SPELKPLP--EDYRQQTFEKTDLKVPAKAKLTKLKMPSQSVEQTYSNEVHCVEEILKEMT 364

Query: 1919 NRGQPK------PILQKQSTFPQSSKDIPDRGAATDEKLQNFAIENTPVCFSHNSSLSSL 1972
            +   P       P   + S FP  +KD     + T  + Q      T     H++S    
Sbjct: 365  HSWPPPLTAIHTPSTAEPSKFPFPTKDSQHVSSVTQNQKQYDTSSKT-----HSNSQQGT 419

Query: 1973 SDIDQENNNKENEPIKETEPPDSQGEPSKPQASGYAPKSFHVEDTPVCFSRNSSLSSLSI 2032
            S + +++       + ++E  DS+  P KP +S   P +      PV  + +SS  S S 
Sbjct: 420  SSMLEDDLQ-----LSDSEDSDSEQTPEKPPSSSAPPSAPQSLPEPVASAHSSSAESEST 474

Query: 2033 -DSEDDLLQECISSAMPKKKKPSRLKGDNEKHSPRNMGGILGEDLTLDLKDIQRPDSEHG 2091
             DS+     E  SS+   ++         E   P      L   LT   +    P+    
Sbjct: 475  SDSDSSSDSESESSSSDSEENEPLETPAPEPEPPTTNKWQLDNWLTKVSQPAAPPEGPRS 534

Query: 2092 LSPDSENFDWKAIQEGANSIVSSLHQAAAAACLSRQASSDSDSILSLKSGISLGSPFHLT 2151
              P   + + K   + A S                Q  S+S                   
Sbjct: 535  TEPPRRHPESKGSSDSATS----------------QEHSES------------------- 559

Query: 2152 PDQEEKPFTSNKGPR----ILKPG----EKSTLETKKIESESKGIKGGKKVYKSLITGKV 2203
              ++  P +S+K PR       PG    +KS  + +  + ++ G K  KK  K+  + + 
Sbjct: 560  --KDPPPKSSSKAPRAPPEAPHPGKRSCQKSPAQQEPPQRQTVGTKQPKKPVKA--SARA 615

Query: 2204 RSNSEISGQMKQPLQANMPSISRGRTMIHIPGVRNSSSSTSPVSKKGPPLKTPASKSPSE 2263
             S + + G+ +  L   +P  SR +T    P V+      +  S +  P   P+S+    
Sbjct: 616  GSRTSLQGEREPGL---LPYGSRDQTSKDKPKVKTKGRPRAAASNEPKPAVPPSSEKKKH 672

Query: 2264 GQT------ATTSPRGAKPSVK----SELSPVARQTSQIGGSSKAPSR-SGSRDSTPSRP 2312
              +      A + P  AK +V+       + V    SQ    S + SR SG R +   + 
Sbjct: 673  KSSLPAPSKALSGPEPAKDNVEDRTPEHFALVPLTESQGPPHSGSGSRTSGCRQAVVVQE 732

Query: 2313 AQQPLSRPIQSPGRNSISPGRNGISPPNKLSQLPRTSSPSTASTKSSGSGKMSYTSPGRQ 2372
              +    P+       +SP R+  +PP +   +  T    +   +  G G        RQ
Sbjct: 733  DSRKDRLPLPLRDTKLLSPLRD--TPPPQSLMVKITLDLLSRIPQPPGKG-------SRQ 783

Query: 2373 MSQQNLTKQTGLSKNASSIPRSESASKGLNQMNNGNGA----NKKVELSRMSSTKSSGSE 2428
               ++  KQ    K  SS  RS  +S  L +   G       NKK+ L +   ++SS S 
Sbjct: 784  RKAED--KQPPAGKKHSSEKRSSDSSSKLAKKRKGEAERDCDNKKIRLEKEIKSQSSSSS 841

Query: 2429 SDRSERPVLVRQSTFIKEAPSPTLRRKLEESASFESLSP------SSRPASPT--RSQAQ 2480
            S   E           K  PS    R   +S+  E L P      S +PA P   RS+ +
Sbjct: 842  SSHKESS---------KTKPS----RPSSQSSKKEMLPPPPVSSSSQKPAKPALKRSRRE 888

Query: 2481 TPVLSPSLPDMSLSTHSSVQAGGWRKLPPNLSPTIEYNDGRPAKRHDIARSHSESPSRLP 2540
                    P  + ST S+ +     K        +E    R +  H  +   + +P  +P
Sbjct: 889  ADTCGQDPPKSASSTKSNHKDSSIPK-----QRRVEGKGSRSSSEHKGSSGDTANPFPVP 943

Query: 2541 INRSGTWK 2548
               +G  K
Sbjct: 944  SLPNGNSK 951



 Score = 51.6 bits (122), Expect = 1e-05
 Identities = 112/524 (21%), Positives = 194/524 (37%), Gaps = 80/524 (15%)

Query: 1188 PSSQKQSFSFSKSSSGQSSKTEHMSSSSENTSTPSSNAKRQNQLHPSSAQSRSGQPQKAA 1247
            P S  +  + + SSS +S  T    SSS++ S  SS+   +N+  P    +   +P    
Sbjct: 454  PQSLPEPVASAHSSSAESESTSDSDSSSDSESESSSSDSEENE--PLETPAPEPEPPTTN 511

Query: 1248 TCKVSSINQETIQTYCVEDTPICFSRCSSLSSLSSAEDEIGCNQTTQEADSANTLQIAEI 1307
              ++ +   +  Q     + P             S E      ++   +DSA + + +E 
Sbjct: 512  KWQLDNWLTKVSQPAAPPEGP------------RSTEPPRRHPESKGSSDSATSQEHSES 559

Query: 1308 KEKIGTRSAEDPVSEVPAVSQHPRTKSSRLQGSSLSSESARHKAVEFSSGAKSPSKSGAQ 1367
            K+     S++ P    P  + HP  +S   Q S    E  + + V  +   K P K+ A+
Sbjct: 560  KDPPPKSSSKAP--RAPPEAPHPGKRS--CQKSPAQQEPPQRQTVG-TKQPKKPVKASAR 614

Query: 1368 TPKSPPEHYVQETPLMFSRCTSVSSLDSFESRS-----IASSVQSEPCSGMVSGIISPSD 1422
                      +E  L+       +S D  + ++      A+S + +P        + PS 
Sbjct: 615  AGSRTSLQGEREPGLLPYGSRDQTSKDKPKVKTKGRPRAAASNEPKPA-------VPPSS 667

Query: 1423 LPDSPGQTMPPSRSKTPPPPPQTAQTKREVPKNKA--PTAE----------KRESGPKQA 1470
                   ++P        P P     +   P++ A  P  E           R SG +QA
Sbjct: 668  EKKKHKSSLPAPSKALSGPEPAKDNVEDRTPEHFALVPLTESQGPPHSGSGSRTSGCRQA 727

Query: 1471 AVNAAVQRVQVLP----DADTLLHFATESTPDGFSCSSSLSALS-LDEP----FIQKDVE 1521
             V     R   LP    D   L        P       +L  LS + +P      Q+  E
Sbjct: 728  VVVQEDSRKDRLPLPLRDTKLLSPLRDTPPPQSLMVKITLDLLSRIPQPPGKGSRQRKAE 787

Query: 1522 LRIMPPVQENDNGNETESEQPKESNENQEKEAEKTIDSEKDLLDDSDDDDIEILEECIIS 1581
             +  PP  +  +  +  S+   +  + ++ EAE+  D++K  L+       EI  +   S
Sbjct: 788  DK-QPPAGKKHSSEKRSSDSSSKLAKKRKGEAERDCDNKKIRLEK------EIKSQSSSS 840

Query: 1582 AMPTKSSRKAK--KPAQTASK---LPPPVARKPSQLPVYKLLPSQNRLQPQKHVSFTPGD 1636
            +   K S K K  +P+  +SK   LPPP     SQ       P++  L+  +  + T G 
Sbjct: 841  SSSHKESSKTKPSRPSSQSSKKEMLPPPPVSSSSQ------KPAKPALKRSRREADTCGQ 894

Query: 1637 DMPRVYCVEGTPINFSTATSLSDLTIESPPNELAAGEGVRGGAQ 1680
            D P+           ST ++  D +I  P      G+G R  ++
Sbjct: 895  DPPKSAS--------STKSNHKDSSI--PKQRRVEGKGSRSSSE 928



 Score = 51.2 bits (121), Expect = 1e-05
 Identities = 143/731 (19%), Positives = 253/731 (34%), Gaps = 143/731 (19%)

Query: 1922 QPKPILQKQSTFPQSSKDIPDRGAATDEKLQNFAIENTPVCFSHNSSLSSLSDIDQENNN 1981
            +P P   +Q TF ++   +P +   T  K+ + ++E T     +++ +  + +I +E  +
Sbjct: 311  KPLPEDYRQQTFEKTDLKVPAKAKLTKLKMPSQSVEQT-----YSNEVHCVEEILKEMTH 365

Query: 1982 KENEPIKETEPPDSQGEPSKPQASGYAPKSFHVEDTPVCFSRNSSLSSLSIDSEDDLLQE 2041
                P+     P S  EPSK         S HV                           
Sbjct: 366  SWPPPLTAIHTP-STAEPSKFPFP--TKDSQHV--------------------------- 395

Query: 2042 CISSAMPKKKKPSRLKGDNEKHSPRNMGGILGEDLTLDLKDIQRPDSEHGLSPDSENFDW 2101
               S++ + +K          +S +    +L +DL   L D +  DSE        +   
Sbjct: 396  ---SSVTQNQKQYDTSSKTHSNSQQGTSSMLEDDL--QLSDSEDSDSEQTPEKPPSSSAP 450

Query: 2102 KAIQEGANSIVSSLHQAAAAACLSRQASSDSDSILSLKSGISLGSPFHLTPDQEEKPFTS 2161
             +  +     V+S H ++A +  +  + S SDS     S  S  +    TP  E +P T+
Sbjct: 451  PSAPQSLPEPVASAHSSSAESESTSDSDSSSDSESESSSSDSEENEPLETPAPEPEPPTT 510

Query: 2162 NKG-----------PRILKPGEKSTLETKKIESESKGIKGGKKVYKSLITGKVRSNSEIS 2210
            NK            P     G +ST E  +   ESKG                 + S+  
Sbjct: 511  NKWQLDNWLTKVSQPAAPPEGPRST-EPPRRHPESKGSSDS-------------ATSQEH 556

Query: 2211 GQMKQPLQANMPSISRGRTMIHIPGVRNSSSSTSPVSKKGPPLKTPASKSPSEGQTATTS 2270
             + K P   +     R       PG R  S   SP  ++ P  +T  +K P +   A+  
Sbjct: 557  SESKDPPPKSSSKAPRAPPEAPHPGKR--SCQKSPAQQEPPQRQTVGTKQPKKPVKASAR 614

Query: 2271 PRGAKPSVKSELSPVARQTSQIGGSSKAPSRSGSRDSTPS-RPAQQPLSRPIQSPGRNSI 2329
              G++ S++ E  P                  GSRD T   +P  +   RP ++   N  
Sbjct: 615  A-GSRTSLQGEREPGLLPY-------------GSRDQTSKDKPKVKTKGRP-RAAASNEP 659

Query: 2330 SPGRNGISPPNKLSQLPRTSSPSTASTKSSGSGKMSYTSPGRQMSQQNLTKQTGLSKNAS 2389
             P      PP+   +  ++S P+ +   S           G + ++ N+  +T   ++ +
Sbjct: 660  KPA----VPPSSEKKKHKSSLPAPSKALS-----------GPEPAKDNVEDRT--PEHFA 702

Query: 2390 SIPRSESASKGLNQMNNGNGANKKVELSRMSSTKSSGSESDRSERPVLVRQSTFIKEAPS 2449
             +P +ES                            SGS +    + V+V++ +     P 
Sbjct: 703  LVPLTESQGP---------------------PHSGSGSRTSGCRQAVVVQEDSRKDRLPL 741

Query: 2450 PTLRRKLEESASFESLSPSSRPASPTRSQAQTPVLSPSLPDMSLSTHSSVQAGGWRKLPP 2509
            P    KL        LSP      P     Q+ ++  +L  +S       +    RK   
Sbjct: 742  PLRDTKL--------LSPLRDTPPP-----QSLMVKITLDLLSRIPQPPGKGSRQRKAED 788

Query: 2510 NLSPTIEYNDGRPAKRHDIARSHSESPSRLPINRSGTWKREHSKHSSSLPRVSTWRRTGS 2569
               P          K+H   +  S+S S+L   R G  +R+       L +    + + S
Sbjct: 789  KQPPA--------GKKHSSEKRSSDSSSKLAKKRKGEAERDCDNKKIRLEKEIKSQSSSS 840

Query: 2570 SSSILSASSESSEKAKSEDEKHVNSISGTKQSKENQVSAKGTWRKIKENEFSPTNSTSQT 2629
            SSS   +S     +  S+  K    +     S  +Q  AK   ++ +    +      ++
Sbjct: 841  SSSHKESSKTKPSRPSSQSSKK-EMLPPPPVSSSSQKPAKPALKRSRREADTCGQDPPKS 899

Query: 2630 VSSGATNGAES 2640
             SS  +N  +S
Sbjct: 900  ASSTKSNHKDS 910



 Score = 42.0 bits (97), Expect = 0.009
 Identities = 63/282 (22%), Positives = 98/282 (34%), Gaps = 25/282 (8%)

Query: 1152 QHEEEERPTNYSIKYNEEKRHVDQPIDYSLKYATDIP---SSQKQSFSFSKSSSGQSSKT 1208
            Q + E++      K++ EKR  D     + K   +      ++K        S   SS +
Sbjct: 783  QRKAEDKQPPAGKKHSSEKRSSDSSSKLAKKRKGEAERDCDNKKIRLEKEIKSQSSSSSS 842

Query: 1209 EHMSSSSENTSTPSSNAKRQNQLHPSSAQSRSGQPQKAATCKVSSINQETIQTYCVEDTP 1268
             H  SS    S PSS + ++  L P    S S +P K A  K S    +T    C +D P
Sbjct: 843  SHKESSKTKPSRPSSQSSKKEMLPPPPVSSSSQKPAKPA-LKRSRREADT----CGQDPP 897

Query: 1269 ICFSRCSSLSSLSSAEDEIGCNQTTQEADSANTLQIAEIKEKIGTRSAEDPVSEVPAVSQ 1328
               S   S    SS   +       +  +   +   +E K   G  +   PV  +P  + 
Sbjct: 898  KSASSTKSNHKDSSIPKQ-------RRVEGKGSRSSSEHKGSSGDTANPFPVPSLPNGNS 950

Query: 1329 HPRTKSSRLQGSSLSSESARHKAVEFSSGAKSPSKSGAQTPKSPPEHYVQETPLMFSRCT 1388
             P        G        +   +      K   K+   T +        E  L F  C 
Sbjct: 951  KP--------GKPQVKFDKQQADLHMREAKKMKQKAELMTDRVGKAFKYLEAVLSFIECG 1002

Query: 1389 SVSSLDSFESRSIASSVQSEPCSGMVSGIISPSDLPDSPGQT 1430
              +  +S  S+S A SV SE    ++  I+S     D+   T
Sbjct: 1003 IATESESQSSKS-AYSVYSETVD-LIKFIMSLKSFSDATAPT 1042



 Score = 32.3 bits (72), Expect = 6.9
 Identities = 87/391 (22%), Positives = 132/391 (33%), Gaps = 52/391 (13%)

Query: 1320 VSEVPAVSQHPRTKSSRLQGSSLSSESARHKAVEFSSGAKSPSKSGAQTPKSPPEHYVQE 1379
            VS V    +   T S     S   + S     ++ S    S S+   QTP+ PP      
Sbjct: 395  VSSVTQNQKQYDTSSKTHSNSQQGTSSMLEDDLQLSDSEDSDSE---QTPEKPPSSSAPP 451

Query: 1380 TPLMFSRCTSVSSLDSFESRSIASSVQSEPCSGMVSGIISPSDLPDSPGQTMPPSRSKTP 1439
            +        +  SL    + + +SS +SE  S   S   S S+   S  +   P  +  P
Sbjct: 452  S--------APQSLPEPVASAHSSSAESESTSDSDSSSDSESESSSSDSEENEPLETPAP 503

Query: 1440 PPPPQTA---QTKREVPKNKAPTAEKRESGPKQAAVNAAVQRVQVLPDADTLLHFATEST 1496
             P P T    Q    + K   P A     GP+           +   D+ T    +    
Sbjct: 504  EPEPPTTNKWQLDNWLTKVSQPAAP--PEGPRSTEPPRRHPESKGSSDSATSQEHSESKD 561

Query: 1497 PDGFSCSSSLSALSLDEPFIQKDVELRIMPPVQENDNGNETESEQPKESNENQEKEAEKT 1556
            P   S SS       + P   K    +  P  QE        ++QPK+  +   +   +T
Sbjct: 562  PPPKS-SSKAPRAPPEAPHPGKR-SCQKSPAQQEPPQRQTVGTKQPKKPVKASARAGSRT 619

Query: 1557 I---DSEKDLLDDSDDDDIEILEECIISAMPTKSSRKAK---KPAQTASKLPPPVARKPS 1610
                + E  LL     D              +K   K K   +P   AS  P P     S
Sbjct: 620  SLQGEREPGLLPYGSRD------------QTSKDKPKVKTKGRPRAAASNEPKPAVPPSS 667

Query: 1611 QLPVYK-LLPSQNRLQPQKHVSFTPGDDMPRVYCVEGTPINFSTATSLSDLTIESPPNEL 1669
            +   +K  LP+     P K +S   G +  +    + TP +F    +L  LT    P   
Sbjct: 668  EKKKHKSSLPA-----PSKALS---GPEPAKDNVEDRTPEHF----ALVPLTESQGPPHS 715

Query: 1670 AAGEGVRGGAQS---GEFEKRDTIPTEGRST 1697
             +G    G  Q+    E  ++D +P   R T
Sbjct: 716  GSGSRTSGCRQAVVVQEDSRKDRLPLPLRDT 746


>gi|57164977 Treacher Collins-Franceschetti syndrome 1 isoform a [Homo
            sapiens]
          Length = 1450

 Score = 67.0 bits (162), Expect = 3e-10
 Identities = 292/1468 (19%), Positives = 484/1468 (32%), Gaps = 225/1468 (15%)

Query: 1131 QEDDYEDDKPTNYSERYSEEEQHEEEERPTNYSIKY-------NEEKRHVDQPIDYSLKY 1183
            +ED     K T  S+  S  E  EEEE     + K        N      D P     K 
Sbjct: 66   EEDAALQAKKTRVSDPISTSESSEEEEEAEAETAKATPRLASTNSSVLGADLPSSMKEKA 125

Query: 1184 ATDIPSSQKQSFSFSKSSSGQSSKTEHMSSSSENTSTPSSNAKRQNQLHPSSAQSRSGQP 1243
              +   + K   S    ++G++        S   ++ PS+N    ++     +    G  
Sbjct: 126  KAETEKAGKTGNSMPHPATGKTVANLLSGKSPRKSAEPSANTTLVSETEEEGSVPAFGAA 185

Query: 1244 QKAATCKVSSINQETIQTYCVEDTPICFSRCSSLSSLSSAEDEIGCNQTTQEADSANTLQ 1303
             K         +  +      EDT       SS S  +  E +        +A S +T +
Sbjct: 186  AKPGMVSAGQADSSS------EDT-------SSSSDETDVEGKPSVKPAQVKASSVSTKE 232

Query: 1304 IAEIKEKIGTRSAEDPVSEVPAVSQHPRTKSSRLQGSSLSSESARHKAVEFSSGAKS--- 1360
                K         D   +V   +  P  ++ + +  S SSE       E  +G +S   
Sbjct: 233  SPARKAAPAPGKVGDVTPQVKGGALPPAKRAKKPEEESESSEEGSESEEEAPAGTRSQVK 292

Query: 1361 ------------------PSKSGAQTPKSPPEHYVQET----PLMFSRCTSVSSLDSFES 1398
                              P K     P         +T    P   S  +S  S DS E 
Sbjct: 293  ASEKILQVRAASAPAKGTPGKGATPAPPGKAGAVASQTKAGKPEEDSESSSEESSDSEEE 352

Query: 1399 RSIASSVQSEPCSGMVSGIISPS----------DLPDSPGQTMP---------------- 1432
               A ++     SG  S + + S            P  PG+T P                
Sbjct: 353  TPAAKALLQAKASGKTSQVGAASAPAKESPRKGAAPAPPGKTGPAVAKAQAGKREEDSQS 412

Query: 1433 -PSRSKTPPPPPQTAQTKREVPKNKAPTAEKRESGPKQAA------VNAAVQRVQVLPDA 1485
                S +    P  A+   + P+ +A +A  +ES  K AA         A  +VQV    
Sbjct: 413  SSEESDSEEEAPAQAKPSGKAPQVRAASAPAKESPRKGAAPAPPRKTGPAAAQVQVGKQE 472

Query: 1486 DTLLHFATESTPDGFSCSSSLSALSLDE-------PFIQKDVELRIMP------PVQEND 1532
            +     + ES  D      +L+A++  +       P ++    + + P      PV    
Sbjct: 473  EDSRSSSEESDSD----REALAAMNAAQVKPLGKSPQVKPASTMGMGPLGKGAGPVPPGK 528

Query: 1533 NGNETESEQPKESNENQEKEAEKTIDSEKDLLDDSDDDDIEILEECIISAMPTKSSRKAK 1592
             G  T S Q  +  E+ E  +E++ DS    +  +     E     I+ A PT S   AK
Sbjct: 529  VGPATPSAQVGKWEEDSESSSEESSDSSDGEVPTAVAPAQEKSLGNILQAKPTSS--PAK 586

Query: 1593 KPAQTASKLPPPV-ARKPSQLPVYKLLPSQNRLQPQKHVSFTPGDDMPRVYCVEGTPINF 1651
             P Q A  +   V A KP          S +    +   + T     P +   +      
Sbjct: 587  GPPQKAGPVAVQVKAEKPMDNSESSEESSDSADSEEAPAAMTAAQAKPALKIPQTKACPK 646

Query: 1652 STATSLSDLTIESPPNELAAGEGVRGGAQSGEFEKRDTIPTEGRSTDEAQGGKTSSVTIP 1711
             T T+ S           A    VR G Q+    K  T  +   S+    GG       P
Sbjct: 647  KTNTTAS-----------AKVAPVRVGTQAP--RKAGTATSPAGSSPAVAGGTQR----P 689

Query: 1712 ELDDNKAEEGDILAECINSAMPKGKSHKPFRVKKIMDQVQQASASSSAPNKNQLDGKKKK 1771
              D + +EE D   E    A+  G++      K +   +Q  +A  S P K  L G+   
Sbjct: 690  AEDSSSSEESDSEEEKTGLAVTVGQA------KSVGKGLQVKAA--SVPVKGSL-GQGTA 740

Query: 1772 PTSPVKPIPQNTEYRTRVRKNADSKNNLNAERVFSDNKDSKKQNLKNNSKVFNDKLPNNE 1831
            P  P K  P  T+ +   +++++S          SD++++     +  + V   +   N 
Sbjct: 741  PVLPGKTGPTVTQVKAEKQEDSESSEE------ESDSEEAAASPAQVKTSVKKTQAKANP 794

Query: 1832 DRVRGSFA---FDSPHHYTPIEGTPYCFSRNDSLSSLDFDDDDVDLSREKAELRKAKENK 1888
               R   A     +P             S +     +    +   L+R  A +    +  
Sbjct: 795  AAARAPSAKGTISAPGKVVTAAAQAKQRSPSKVKPPVRNPQNSTVLARGPASVPSVGKAV 854

Query: 1889 ESEAKVTSHTELTSNQQSANKTQAIAKQPINRGQPKPILQKQSTFPQSSKDIPDRGAATD 1948
             + A+  +  E  S             + + + +P     +       +K+ P +GAA  
Sbjct: 855  ATAAQAQTGPEEDSGSSEEESDSEEEAETLAQVKPSGKTHQIRAALAPAKESPRKGAAPT 914

Query: 1949 E--KLQNFAIENTPVCFSHNSSLSSLSDIDQENNNKENEPIKETEPPDSQGEPSK-PQAS 2005
               K    A +      S +SS  S SD +        + IK   PP    +P++ P   
Sbjct: 915  PPGKTGPSAAQAGKQDDSGSSSEESDSDGEAPAAVTSAQVIK---PPLIFVDPNRSPAGP 971

Query: 2006 GYAPKSFHVEDTP--VCFSRNSSLSSLSIDSEDDLL--QECIS-----------SAMPK- 2049
               P       TP     S +++ SS S   ++D++   +C++           +A P+ 
Sbjct: 972  AATPAQAQAASTPRKARASESTARSSSSESEDEDVIPATQCLTPGIRTNVVTMPTAHPRI 1031

Query: 2050 KKKPSRLKGDNEKHSPRNMGGILGEDLTLDLKDIQRPDSEHGLSPDSENFDWKAIQEGAN 2109
              K S     + K S R   G   E     +      DS  G  P +         +G N
Sbjct: 1032 APKASMAGASSSKESSRISDGKKQEGPATQV------DSAVGTLPATSPQSTSVQAKGTN 1085

Query: 2110 SIVSSLHQAAAAACLSRQASSDSDSILSLKSGISLGSPFHLTPDQEEKPFTSNKGPRILK 2169
             +          A  + ++S DS+      S  S GS       Q  K      GP    
Sbjct: 1086 KLRKPKLPEVQQATKAPESSDDSED----SSDSSSGSEEDGEGPQGAKS-AHTLGP---T 1137

Query: 2170 PGEKSTL--ETKKIESESKGIKGGKKVYKSLIT-GKVRSNSEISGQMKQPLQANMPSISR 2226
            P    TL  ET    SE   +   + +    +T G   +NS+ S     P   + PS+S 
Sbjct: 1138 PSRTETLVEETAAESSEDDVVAPSQSLLSGYMTPGLTPANSQAS--KATPKLDSSPSVSS 1195

Query: 2227 GRTMIHIP-------------------GVRNSSSSTSPVS----KKG---PPLKTPASKS 2260
                   P                   G + ++S T+P      KKG   P   T A +S
Sbjct: 1196 TLAAKDDPDGKQEAKPQQAAGMLSPKTGGKEAASGTTPQKSRKPKKGAGNPQASTLALQS 1255

Query: 2261 PSE----GQTATTSPRGAKPSVKSELSPVARQ-TSQIGGSSKAPSRSGSRDSTPSRPAQQ 2315
                   GQ    +    + SV   L+ +  Q   ++  ++K  SR G           Q
Sbjct: 1256 NITQCLLGQPWPLNEAQVQASVVKVLTELLEQERKKVVDTTKESSRKGWESRKRKLSGDQ 1315

Query: 2316 PLSRPIQSPGRNSISPGRNGISPPNKLSQLPRTSSPSTASTKSSGSGKMSYTSPGRQMSQ 2375
            P +R  +S  +  +  G  G            + SP   ST S G  K       R  + 
Sbjct: 1316 PAARTPRSKKKKKLGAGEGG----------EASVSPEKTSTTSKGKAK-------RDKAS 1358

Query: 2376 QNLTKQTG---LSKNASSIPRSESASKGLNQMNNGNGANKKVELSRMSSTKSSGSESDRS 2432
             ++ ++ G   L    +     E   KG+  +  G+ +N K +  +  S K    +  + 
Sbjct: 1359 GDVKEKKGKGSLGSQGAKDEPEEELQKGMGTVEGGDQSNPKSKKEKKKSDKRKKDKEKKE 1418

Query: 2433 ERPVLVRQSTFIKEAPSPTLRRKLEESA 2460
            ++    + ST   E+PS   ++K +++A
Sbjct: 1419 KKKKAKKASTKDSESPSQKKKKKKKKTA 1446



 Score = 55.8 bits (133), Expect = 6e-07
 Identities = 191/1024 (18%), Positives = 346/1024 (33%), Gaps = 155/1024 (15%)

Query: 1877 EKAELRKAKENKESEAKVTSHTELTSNQQSANKTQAIAKQPINRGQPKPILQKQSTFPQS 1936
            E    RKA+E+   +AK T  ++  S  +S+ + +  A+    +  P+      S     
Sbjct: 58   ELGRKRKAEEDAALQAKKTRVSDPISTSESSEEEEE-AEAETAKATPRLASTNSSVL--- 113

Query: 1937 SKDIPDRGAATDEKLQNFAIENTPVCFSHNSSLSSLSDIDQENNNKENEPIKETEPPDSQ 1996
              D+P   ++  EK +    E      + NS     +     N      P K  EP  + 
Sbjct: 114  GADLP---SSMKEKAK---AETEKAGKTGNSMPHPATGKTVANLLSGKSPRKSAEPSANT 167

Query: 1997 GEPSKPQASGYAPKSFHVEDTP--VCFSRNSSLSSLSIDSEDDLLQECISSAMPKKKKPS 2054
               S+ +  G  P +F     P  V   +  S S  +  S D+   E   S  P + K S
Sbjct: 168  TLVSETEEEGSVP-AFGAAAKPGMVSAGQADSSSEDTSSSSDETDVEGKPSVKPAQVKAS 226

Query: 2055 RLKGDNEKHSPRNMG----GILGEDLTLDLKDIQRPDSEHGLSPDSENFDWKAIQEGANS 2110
             +   + K SP        G +G D+T  +K    P ++    P+ E+   ++ +EG+ S
Sbjct: 227  SV---STKESPARKAAPAPGKVG-DVTPQVKGGALPPAKRAKKPEEES---ESSEEGSES 279

Query: 2111 IVSSLHQAAAAACLSRQASSDSDSILSLKSGISLGSPFHLTPDQEEKPFTSNKGPRILKP 2170
                  + A A   S+  +S+    +   S  + G+P               KG     P
Sbjct: 280  -----EEEAPAGTRSQVKASEKILQVRAASAPAKGTP--------------GKGATPAPP 320

Query: 2171 GEKSTLETKKIESESKGIKGGKKVYKSLITGKVRSNSEISGQMKQPLQANMPSISRGRTM 2230
            G+        + S++K              GK   +SE S +     +   P+    + +
Sbjct: 321  GKAGA-----VASQTKA-------------GKPEEDSESSSEESSDSEEETPA---AKAL 359

Query: 2231 IHIPGVRNSSSSTSPVSKKGPPLKTPASKSPSEGQTATTSPRGAKPSVKSELSPVARQTS 2290
            +       +S  TS V     P K    K  +      T P  AK             + 
Sbjct: 360  LQA----KASGKTSQVGAASAPAKESPRKGAAPAPPGKTGPAVAKAQAGKREEDSQSSSE 415

Query: 2291 QIGGSSKAPSRSGSRDSTPS-RPAQQPLSRPIQSPGRNSISPGRNGISPPNKLSQLPRTS 2349
            +     +AP+++      P  R A  P     +SP + +         P     Q+ +  
Sbjct: 416  ESDSEEEAPAQAKPSGKAPQVRAASAPAK---ESPRKGAAPAPPRKTGPAAAQVQVGKQE 472

Query: 2350 SPSTASTKSSGS----------------GKMSYTSPGRQMSQQNLTKQTGLSKNASSIPR 2393
              S +S++ S S                GK     P   M    L K  G        P 
Sbjct: 473  EDSRSSSEESDSDREALAAMNAAQVKPLGKSPQVKPASTMGMGPLGKGAGPVPPGKVGPA 532

Query: 2394 SESASKGLNQMNNGNGANKKVELSRMSSTKSSGSESDRSERPVLVRQSTFIKEAPSP--- 2450
            + SA  G  + ++ + + +  + S      +     ++S   +L  + T       P   
Sbjct: 533  TPSAQVGKWEEDSESSSEESSDSSDGEVPTAVAPAQEKSLGNILQAKPTSSPAKGPPQKA 592

Query: 2451 -------TLRRKLEESASFESLSPSS----RPASPTRSQAQTPVLSPSLPDMSLSTHSSV 2499
                      + ++ S S E  S S+     PA+ T +QA+  +  P        T+++ 
Sbjct: 593  GPVAVQVKAEKPMDNSESSEESSDSADSEEAPAAMTAAQAKPALKIPQTKACPKKTNTTA 652

Query: 2500 QA--------------GGWRKLPPNLSPTIEYNDGRPAKRHDIARSHSESPSR------- 2538
             A               G    P   SP +     RPA   + + S  ES S        
Sbjct: 653  SAKVAPVRVGTQAPRKAGTATSPAGSSPAVAGGTQRPA---EDSSSSEESDSEEEKTGLA 709

Query: 2539 LPINRSGTWKREHSKHSSSLPRVSTWRRTGSSSSILSASSESSEKAKSEDEKHVNSISGT 2598
            + + ++ +  +     ++S+P V      G++  +   +  +  + K+E ++   S    
Sbjct: 710  VTVGQAKSVGKGLQVKAASVP-VKGSLGQGTAPVLPGKTGPTVTQVKAEKQEDSESSEEE 768

Query: 2599 KQSKENQVSAKGTWRKIKENEFSPTNSTSQTVSSGATNGAESKTL-----IYQMAPAVSK 2653
              S+E   S       +K+ +     + ++  S+  T  A  K +       Q +P+  K
Sbjct: 769  SDSEEAAASPAQVKTSVKKTQAKANPAAARAPSAKGTISAPGKVVTAAAQAKQRSPSKVK 828

Query: 2654 TEDVWVRIEDCPINNPRS----GRSPTGNTPPVIDSVSEKANPNIKDSKDNQAKQNVGNG 2709
                       P+ NP++     R P  + P V  +V+  A       +D+ + +   + 
Sbjct: 829  P----------PVRNPQNSTVLARGP-ASVPSVGKAVATAAQAQTGPEEDSGSSEEESDS 877

Query: 2710 SVPMRTVGLENRLNSFIQVDAPDQKGTEIKPGQNNPVPVSETNESSIVERTPFSSSSSSK 2769
                 T+          Q+ A      E       P P  +T  S+        S SSS+
Sbjct: 878  EEEAETLAQVKPSGKTHQIRAALAPAKESPRKGAAPTPPGKTGPSAAQAGKQDDSGSSSE 937

Query: 2770 HSSPSGTVAARVTPFN--------YNPSPRKSSADSTSARPSQIPTPVNNNTKKRDSKTD 2821
             S   G   A VT            +P+   +   +T A+     TP      +  +++ 
Sbjct: 938  ESDSDGEAPAAVTSAQVIKPPLIFVDPNRSPAGPAATPAQAQAASTPRKARASESTARSS 997

Query: 2822 STES 2825
            S+ES
Sbjct: 998  SSES 1001



 Score = 37.4 bits (85), Expect = 0.21
 Identities = 74/346 (21%), Positives = 118/346 (34%), Gaps = 61/346 (17%)

Query: 2540 PINRSGTWKREHSKHSSSLPRVSTWRRTGSSSSILSASSESS--EKAKSEDEKH------ 2591
            PI+ S + + E    + +    +T R   ++SS+L A   SS  EKAK+E EK       
Sbjct: 81   PISTSESSEEEEEAEAETAK--ATPRLASTNSSVLGADLPSSMKEKAKAETEKAGKTGNS 138

Query: 2592 ----------VNSISGTKQSKENQVSAKGTWRKIKENEFSPTN----------STSQTVS 2631
                       N +SG    K  + SA  T     E E S             S  Q  S
Sbjct: 139  MPHPATGKTVANLLSGKSPRKSAEPSANTTLVSETEEEGSVPAFGAAAKPGMVSAGQADS 198

Query: 2632 SGATNGAESKTLIYQMAPAV--SKTEDVWVRIEDCPINNPRSGRSPTGNTPPVIDSVSEK 2689
            S     + S     +  P+V  ++ +   V  ++ P           G+  P +   +  
Sbjct: 199  SSEDTSSSSDETDVEGKPSVKPAQVKASSVSTKESPARKAAPAPGKVGDVTPQVKGGALP 258

Query: 2690 ANPNIKDSKDNQAKQNVGNGSVPMRTVGLENRLNS---FIQVDA--------PDQKGTEI 2738
                 K  ++       G+ S      G  +++ +    +QV A        P +  T  
Sbjct: 259  PAKRAKKPEEESESSEEGSESEEEAPAGTRSQVKASEKILQVRAASAPAKGTPGKGATPA 318

Query: 2739 KPGQNNPVPVSETNESSIVERTPFSSSSSS---------------KHSSPSGTVAARVTP 2783
             PG+   V  S+T      E +  SS  SS               K S  +  V A   P
Sbjct: 319  PPGKAGAV-ASQTKAGKPEEDSESSSEESSDSEEETPAAKALLQAKASGKTSQVGAASAP 377

Query: 2784 FNYNPSPRKSSADSTSARPSQIPTPVNNNTKKRDSKTDSTESSGTQ 2829
                 SPRK +A +   +            ++ DS++ S ES   +
Sbjct: 378  AK--ESPRKGAAPAPPGKTGPAVAKAQAGKREEDSQSSSEESDSEE 421


>gi|239743293 PREDICTED: mucin 12 [Homo sapiens]
          Length = 5478

 Score = 65.9 bits (159), Expect = 6e-10
 Identities = 161/764 (21%), Positives = 274/764 (35%), Gaps = 88/764 (11%)

Query: 2125 SRQASSDSDSILSLKSGISLGSPFHLTPDQEEKPFTSNKGPRILKPGEKSTLETKKIE-- 2182
            S+++++   S  S  + +S GS   L+  QE   F SN G         ST  +  +E  
Sbjct: 1047 SQESTTSHSSSGSTDTALSPGSTTALSFGQESTTFHSNPGSTHTTLFPDSTTSSGIVEAS 1106

Query: 2183 ------------------SESKGIKGGKKVYKSLITGKVRSNSEISGQMKQPLQANMPSI 2224
                              S S G++G    +++       + S  S       ++     
Sbjct: 1107 TRVHSSTGSPRTTLSPASSTSPGLQGESTAFQTHPASTHTTPSPPSTATAPVEESTTYHR 1166

Query: 2225 SRGRT-MIHIPGVRNSSSSTSPVSKKGPPLKTPASKSPSEGQTATTSPRGAKPSVKSELS 2283
            S G T   H P    +SS+TS  S+K     +    S +   +A ++  G   S  S +S
Sbjct: 1167 SPGSTPTTHFP----ASSTTSGHSEKSTIFHSSPDASGTTPSSAHSTTSGRGESTTSRIS 1222

Query: 2284 PVARQTSQIGGSSKAPSRSGSRDSTPSRPAQ-----QPLSRPIQSPGRNSIS----PGRN 2334
            P + + + + GS+  P  S +  +  S P        P S      G  S +    PG  
Sbjct: 1223 PGSTEITTLPGSTTTPGLSEASTTFYSSPRSPTTTLSPASMTSLGVGEESTTSRSQPGST 1282

Query: 2335 GISPPNKLSQLPRTSSPSTASTKSS-GSGKMSYTSPGRQMSQQNLTKQTGLSKNAS---S 2390
              +     +  P  S  ST    SS GS + +        S       T  S+ AS   +
Sbjct: 1283 HSTVSPASTTTPGLSEESTTVYSSSRGSTETTVFPHSTTTSVHGEEPTTFHSRPASTHTT 1342

Query: 2391 IPRSESASKGLNQMNN---GNGANKKVELSRMSSTKSSGSESDRSERPVLVRQSTFIKEA 2447
            +   +S + GL + +    G+ A+ +  L    +T   G ES           ST  K +
Sbjct: 1343 LFTEDSTTSGLTEESTAFPGSPASTQTGLPATLTTADLGEESTTFPSS---SGSTGTKLS 1399

Query: 2448 PSPTLRRKLEESASFESLSPSSR-----PASPT----RSQAQTPVLSPSLPDMSLSTHSS 2498
            P+ +    L   ++   LSPSS      P SPT      ++ T   SP  PD +LS  ++
Sbjct: 1400 PARSTTSGLVGESTPSRLSPSSTETTTLPGSPTTPSLSEKSTTFYTSPRSPDATLSPATT 1459

Query: 2499 VQAGGWRKLPPNLSPTIEYNDGRPAKRHDIARSHSESPSRLPINRSGTWKREHSKHSSSL 2558
              +G        +S     +  +P   H  A   S + S L    + +   + S  ++  
Sbjct: 1460 TSSG--------VSEESSTSHSQPGSTHTTAFPDSTTTSDLSQEPTTSHSSQGSTEATLS 1511

Query: 2559 PRVSTWRRTGSSSSILSASSESSEKAKSEDEKHVNSISGTKQSKENQVSAKGTWRKIKEN 2618
            P  +T    G  S+   +S   +E     D+      SG  ++     S+ G+       
Sbjct: 1512 PGSTTASSLGQQSTTFHSSPGDTETTLLPDD---TITSGLVEASTPTHSSTGSLH----- 1563

Query: 2619 EFSPTNSTSQTVSSGATNGAESKTLIYQMAPAVSKTEDVWVRIEDCPINNPRSGRSPTGN 2678
                   T+ T +S  + G + ++  +Q  P+ S T          P+    +  S   +
Sbjct: 1564 -------TTLTPASSTSAGLQEESTTFQSWPSSSDTTPSPPGTTAAPVEVSTTYHSRPSS 1616

Query: 2679 TPPVIDSVSEKANPNIKDSKD-NQAKQNVGNGSVPMRTVGLENRLNSFIQVDAPDQKGTE 2737
            TP    S S       ++S   + +    G    P R+        + + V  P      
Sbjct: 1617 TPTTHFSASSTTLGRSEESTTVHSSPGATGTALFPTRSA-------TSVLVGEPTTSPIS 1669

Query: 2738 IKPGQNNPVPVSETNESSIVERTPFSSSSSSKHS--SPSGTVAARVTPFNYNPSPRKSSA 2795
                +   +P S T      + T F SS  S  +  SP+ T ++ V+  +     R  S 
Sbjct: 1670 SGSTETTALPGSTTTAGLSEKSTTFYSSPRSPDTTLSPASTTSSGVSEESTTSHSRPGST 1729

Query: 2796 DSTSARPSQIPTPVNNNTKKRDSKTDSTESSGTQSPKRHSGSYL 2839
             +T+   S     V+  +    S   ST++  T SP   + S L
Sbjct: 1730 HTTAFPGSTTMPGVSQESTASHSSPGSTDT--TLSPGSTTASSL 1771



 Score = 65.5 bits (158), Expect = 7e-10
 Identities = 153/766 (19%), Positives = 278/766 (36%), Gaps = 92/766 (12%)

Query: 2125 SRQASSDSDSILSLKSGISLGSPFHLTPDQEEKPFTSNKGPRILKPGEKSTLETKKIE-- 2182
            S+++++   S  S  + +S GS   L+  QE   F S+ G         ST  +  +E  
Sbjct: 3687 SQESTTSHSSSGSTDTALSPGSTTALSFGQESTTFHSSPGSTHTTLFPDSTTSSGIVEAS 3746

Query: 2183 ------------------SESKGIKGGKKVYKSLITGKVRSNSEISGQMKQPLQANMPSI 2224
                              S S G++G    +++       + S  S       ++     
Sbjct: 3747 TRVHSSTGSPRTTLSPASSTSPGLQGESTAFQTHPASTHTTPSPPSTATAPVEESTTYHR 3806

Query: 2225 SRGRT-MIHIPGVRNSSSSTSPVSKKGPPLKTPASKSPSEGQTATTSPRGAKPSVKSELS 2283
            S G T   H P    +SS+TS  S+K     +    S +   +A ++  G   S  S +S
Sbjct: 3807 SPGSTPTTHFP----ASSTTSGHSEKSTIFHSSPDASGTTPSSAHSTTSGRGESTTSRIS 3862

Query: 2284 PVARQTSQIGGSSKAPSRSGSRDSTPSRPAQQPLSRPIQSPGRNSISPGRNGISPPNKLS 2343
            P + + + + GS+  P  S +  +  S P     +  +      S+  G    +  ++  
Sbjct: 3863 PGSTEITTLPGSTTTPGLSEASTTFYSSPRSP--TTTLSPASMTSLGVGEESTTSRSQPG 3920

Query: 2344 QLPRTSSPSTASTK--SSGSGKMSYTSPGRQMS-------------QQNLTKQTGLSKNA 2388
                T SP++ +T   S  S  +  +SPG   +             ++  T  +  +   
Sbjct: 3921 STHSTVSPASTTTPGLSEESTTVYSSSPGSTETTVFPRSTTTSVRREEPTTFHSRPASTH 3980

Query: 2389 SSIPRSESASKGLNQMNN---GNGANKKVELSRMSSTKSSGSESDRSERPVLVRQSTFIK 2445
            +++   +S + GL + +    G+ A+ +  L    +T   G ES           ST  K
Sbjct: 3981 TTLFTEDSTTSGLTEESTAFPGSPASTQTGLPATLTTADLGEESTTFPSS---SGSTGTK 4037

Query: 2446 EAPSPTLRRKLEESASFESLSPSSR-----PASPT----RSQAQTPVLSPSLPDMSLSTH 2496
             +P+ +    L   ++   LSPSS      P SPT      ++ T   SP  PD +LS  
Sbjct: 4038 LSPARSTTSGLVGESTPSRLSPSSTETTTLPGSPTTPSLSEKSTTFYTSPRSPDATLSPA 4097

Query: 2497 SSVQAGGWRKLPPNLSPTIEYNDGRPAKRHDIARSHSESPSRLPINRSGTWKREHSKHSS 2556
            ++  +G        +S     +  +P   H  A   S + S L    + +   + S  ++
Sbjct: 4098 TTTSSG--------VSEESSTSHSQPGSTHTTAFPDSTTTSGLSQEPTTSHSSQGSTEAT 4149

Query: 2557 SLPRVSTWRRTGSSSSILSASSESSEKAKSEDEKHVNSISGTKQSKENQVSAKGTWRKIK 2616
              P  +T    G  S+   +S   +E     D+      SG  ++     S+ G+     
Sbjct: 4150 LSPGSTTASSLGQQSTTFHSSPGDTETTLLPDD---TITSGLVEASTPTHSSTGSLH--- 4203

Query: 2617 ENEFSPTNSTSQTVSSGATNGAESKTLIYQMAPAVSKTEDVWVRIEDCPINNPRSGRSPT 2676
                     T+ T +S  + G + ++  +Q  P+ S T          P+    +  S  
Sbjct: 4204 ---------TTLTPASSTSTGLQEESTTFQSWPSSSDTTPSPPSTTAVPVEVSTTYHSRP 4254

Query: 2677 GNTPPVIDSVSEKANPNIKDSKD-NQAKQNVGNGSVPMRTVGLENRLNSFIQVDAPDQKG 2735
             +TP    S S       ++S   + +    G    P R+        + + V  P    
Sbjct: 4255 SSTPTTHFSASSTTLGRSEESTTVHSSPGATGTALFPTRSA-------TSVLVGEPTTSP 4307

Query: 2736 TEIKPGQNNPVPVSETNESSIVERTPFSSSSSSKHS--SPSGTVAARVTPFNYNPSPRKS 2793
                  +   +P S T      + T F SS  S  +  SP+ T ++ V+  +     R  
Sbjct: 4308 ISSGSTETTALPGSTTTAGLSEKSTTFYSSPRSPDTTLSPASTTSSGVSEESTTSHSRPG 4367

Query: 2794 SADSTSARPSQIPTPVNNNTKKRDSKTDSTESSGTQSPKRHSGSYL 2839
            S  +T+   S     V+  +    S   ST++  T SP   + S L
Sbjct: 4368 SMHTTAFPSSTTMPGVSQESTASHSSPGSTDT--TLSPGSTTASSL 4411



 Score = 64.3 bits (155), Expect = 2e-09
 Identities = 138/656 (21%), Positives = 249/656 (37%), Gaps = 75/656 (11%)

Query: 2216 PLQANMPSISRGRTMIH-IPGVRNSSSS--TSPVSKKGPPLKTPASKSPSEGQTATTS-P 2271
            P    MP +S+  T  H IPG  +++ S  T+  S  GP   T  S   S G T TT  P
Sbjct: 324  PDSTTMPGVSQESTASHSIPGSTDTTLSPGTTTPSSLGPESTTFHS---SPGYTKTTRLP 380

Query: 2272 RGAKPSVKSELSPVARQTSQIGGSSKAPSRSGSRDSTPSRPAQQPLSRPIQSPGRNSISP 2331
                 S   E S     ++    ++ +PS S + +  P+     P S+          SP
Sbjct: 381  DNTTTSGLLEASTPVHSSTGSPHTTLSPSSSTTHEGEPTTFQSWPSSK--------DTSP 432

Query: 2332 GRNGISPPN-KLSQLPRTSSPSTASTKSSGSGKMSYTSPGRQMSQQNLTKQTGLSKNASS 2390
              +G +    KLS    +S  ST +T  S S     T+ G   S+++    +     A++
Sbjct: 433  APSGTTSAFVKLSTTYHSSPSSTPTTHFSASS----TTLGH--SEESTPVHSSPVATATT 486

Query: 2391 IPRSESASKGLNQMNNGNGANKKVELSRMSSTKSSGSESDRSERPVLVRQSTFIKEAPSP 2450
             P + SA+ G   +      ++    ++      S + S  SE       ST   ++ +P
Sbjct: 487  PPPARSATSG--HVEESTAYHRSPGSTQTMHFPESSTTSGHSEESATFHGSTTHTKSSTP 544

Query: 2451 TLRRKLEESASFESLSPSSRPASPTRSQAQTPVLSPSLPDMSLSTHSSVQAGGWRKLPPN 2510
            +    L  ++   SL  +      T  +  + +   S  + S ++HSS  A     LP  
Sbjct: 545  STTAALAHTSYHSSLGSTET----THFRDSSTISGRS--EESKASHSSPDAMATTVLPAG 598

Query: 2511 LSPTIEYNDGRPAKRHDIARSHSESPSRLPINRSGTWKREHSKHSSSLPRVSTWRRTGSS 2570
             +P++   D  P+       S S   + LP + +     E S    S PR        +S
Sbjct: 599  STPSVLVGDSTPSP----ISSGSMETTALPGSTTKPGLSEKSTTFYSSPRSPDTTHLPAS 654

Query: 2571 SSILSASSESSEKAKSEDEKHVNSISG--TKQSKENQVSAKGTWRKIKENEFSPTNSTSQ 2628
             +    S ES+         H  +  G  T      + +A  +     +   SP ++T+ 
Sbjct: 655  MTSSGVSEESTTSHSRPGSTHTTAFPGSTTMPGLSQESTASHSSPGPTDTTLSPGSTTAS 714

Query: 2629 TVSSGATN-----GAESKTLIYQMAPAVSKTEDVWVRIEDCPIN----NPRSGRSPTGNT 2679
            ++    T      G+   TL+     A    E         P++    +P +  SP G+T
Sbjct: 715  SLGPEYTTFHSRPGSTETTLLPDNTTASGLLE------ASMPVHSSTRSPHTTLSPAGST 768

Query: 2680 PPVIDSVSEKANPNIKDSK-----------DNQAKQNVGNGSVPMRTVGLENRLNSFIQV 2728
                +S +  + P+ KD++           +     +    S+P   +   +  +  ++ 
Sbjct: 769  TRQGESTTFHSWPSSKDTRPAPPTTTSAFVEPSTTSHGSPSSIPTTHISARSTTSGLVE- 827

Query: 2729 DAPDQKGTEIKPGQNNPVPVSETNESSIVERTPFSSSSSSKH---SSPSGTVAARVTPFN 2785
               +       PG    +   E++ +S       +S SS+ H   S+PS T A    P +
Sbjct: 828  ---ESTTYHSSPGSTQTMHFPESDTTSGRGEESTTSHSSTTHTISSAPSTTSALVEEPTS 884

Query: 2786 YNPSPRKSSADSTSARPSQIPTPVNNNTKKRDSKTDSTESSGT-QSPKRHSGSYLV 2840
            Y+ SP    + +T+  P    T  +  +++  +   S +++GT   P R + S L+
Sbjct: 885  YHSSP---GSTATTHFPDSSTT--SGRSEESTASHSSQDATGTIVLPARSTTSVLL 935



 Score = 61.2 bits (147), Expect = 1e-08
 Identities = 146/654 (22%), Positives = 246/654 (37%), Gaps = 93/654 (14%)

Query: 2234 PGVRNSSSSTSPVSKKGPPLKTPASKSPSE-GQTATT-SPRGAKPS------VKSELSPV 2285
            PG   S+ +  P +     L   ++  PS  G T TT SP  +  S        S LSP 
Sbjct: 2918 PGSPASTQTGLPATLTTADLGEESTTFPSSSGSTGTTLSPARSTTSGLVGESTPSRLSPS 2977

Query: 2286 ARQTSQIGGSSKAPSRS----------GSRDSTPSRPAQQPLSRPIQSPGRNSISPGRNG 2335
            + +T+ + GS   PS S           S D+T S PA    S   +    +   PG   
Sbjct: 2978 STETTTLPGSPTTPSLSEKSTTFYTSPRSPDATLS-PATTTSSGVSEESSTSHSQPGSTH 3036

Query: 2336 ISPPNKLSQLPRTSSPSTASTKSSGSGKMSYTSPG----RQMSQQNLTKQTGLSKNASSI 2391
             +     +     S   TAS  S GS + +  SPG      + QQ+ T  +      +++
Sbjct: 3037 TTAFPDSTTTSGLSQEPTASHSSQGSTEAT-LSPGSTTASSLGQQSTTFHSSPGDTETTL 3095

Query: 2392 PRSESASKGLNQMNNGNGANKKVELSRMSSTKSSGSESDRSERPVLVRQSTFIKEAPSP- 2450
               ++ + GL + +    ++    L    +  SS S   + E        +     PSP 
Sbjct: 3096 LPDDTITSGLVEASTPTHSSTG-SLHTTLTPASSTSAGLQEESTTFQSWPSSSDTTPSPP 3154

Query: 2451 -TLRRKLEESASFESLSPSSRPASPTRSQAQTPVLSPSLPDMSLSTHSSVQAGGWRKLPP 2509
             T    +E S ++ S  PSS P   T   A +  L  S  + S + HSS  A G    P 
Sbjct: 3155 GTTAAPVEVSTTYHS-RPSSTPT--THFSASSTTLGRS--EESTTVHSSPGATGTALFPT 3209

Query: 2510 NLSPTIEYNDGRPAKRHDIARSHSESPSRLPINRSGTWKREHSKHSSSLPRVSTWRRTGS 2569
              + ++    G P        S S   + LP + +     E S    S PR      + +
Sbjct: 3210 RSATSVLV--GEPTT--SPISSGSTETTALPGSTTTAGLSEKSTTFYSSPRSPDTTLSPA 3265

Query: 2570 SSSILSASSESSEKAKSEDEKHVNSISGTKQSKENQVSAKGTWRKIKENEFSPTNSTSQT 2629
            S++    S ES+         H  +  G+        +  G  ++   +  SP  ST  T
Sbjct: 3266 STTSSGVSEESTTSHSRPGSTHTTAFPGS-------TTMPGVSQESTASHSSP-GSTDTT 3317

Query: 2630 VSSGATN----GAESKTLIYQMAPAVSKTEDV-------WVRIEDCPIN----NPRSGRS 2674
            +S G+T     G ES T  +   P  ++T  +        +     P++    +P +  S
Sbjct: 3318 LSPGSTTASSLGPESTT--FHSGPGSTETTLLPDNTTASGLLEASTPVHSSTGSPHTTLS 3375

Query: 2675 PTGNTPPVIDSVSEKANPNIKDSKDNQAKQNVGNGSVPMRTVGLENRLNSFIQVDAPDQK 2734
            P G+T    +S + ++ PN KD+                 T       ++F+++      
Sbjct: 3376 PAGSTTRQGESTTFQSWPNSKDT-----------------TPAPPTTTSAFVELSTTSHG 3418

Query: 2735 GTEIKPGQN---NPVPVSETNESSIVERTPFSSSS--SSKHSSPSGTVAARVTPFNYNPS 2789
                 P  +   +   +  + ES+ V  +P ++++  S   S+ SG V    T   Y+ S
Sbjct: 3419 SPSSTPTTHFSASSTTLGRSEESTTVHSSPVATATTPSPARSTTSGLVEESTT---YHSS 3475

Query: 2790 PRKS------SADSTSARPSQIPTPVNNNTKKRDSKTDSTESSGTQSPKRHSGS 2837
            P  +       +D+TS R  +  T  +++T    S   ST S+  + P  +  S
Sbjct: 3476 PGSTQTMHFPESDTTSGRGEE-STTSHSSTTHTISSAPSTTSALVEEPTSYHSS 3528



 Score = 59.3 bits (142), Expect = 5e-08
 Identities = 163/829 (19%), Positives = 283/829 (34%), Gaps = 154/829 (18%)

Query: 2125 SRQASSDSDSILSLKSGISLGSPFHLTPDQEEKPFTSNKGPRILKPGEKSTLETKKIE-- 2182
            S+++++   S  S  + +S GS   L+  QE   F S+ G         ST  +  +E  
Sbjct: 2130 SQESTTSHSSPGSTDTALSPGSTTALSFGQESTTFHSSPGSTHTTLFPDSTTSSGIVEAS 2189

Query: 2183 ------------------SESKGIKGGKKVYKSLITGKVRSNSEISGQMKQPLQANMPSI 2224
                              S S G++G    +++       + S  S       ++     
Sbjct: 2190 TRVHSSTGSPRTTLSPASSTSPGLQGESTAFQTHPASTHTTPSPPSTATAPVEESTTYHR 2249

Query: 2225 SRGRT-MIHIPGVRNSSSSTSPVSKKGPPLKTPASKSPSEGQTATTSPRGAKPSVKSELS 2283
            S G T   H P    +SS+TS  S+K     +    S +   +A ++  G   S  S +S
Sbjct: 2250 SPGSTPTTHFP----ASSTTSGHSEKSTIFHSSPDASGTTPSSAHSTTSGRGESTTSRIS 2305

Query: 2284 PVARQTSQIGGSSKAPSRSGSRDSTPSRPAQQPLSRPIQSPGRNSISPGRNGISPPNKLS 2343
            P + + + + GS+  P  S +  +  S P     +  +      S+  G    +  ++  
Sbjct: 2306 PGSTEITTLPGSTTTPGLSEASTTFYSSPRSP--TTTLSPASMTSLGVGEESTTSRSQPG 2363

Query: 2344 QLPRTSSPSTASTK--SSGSGKMSYTSPGRQ-------------MSQQNLTKQTGLSKNA 2388
                T SP++ +T   S  S  +  +SPG                 ++  T  +  +   
Sbjct: 2364 STHSTVSPASTTTPGLSEESTTVYSSSPGSTETTVFPRTPTTSVRGEEPTTFHSRPASTH 2423

Query: 2389 SSIPRSESASKGLNQMNN---GNGANKKVELSRMSSTKSSGSESD--------------- 2430
            +++   +S + GL + +    G+ A+ +  L    +T   G ES                
Sbjct: 2424 TTLFTEDSTTSGLTEESTAFPGSPASTQTGLPATLTTADLGEESTTFPSSSGSTGTTLSP 2483

Query: 2431 -RSERPVLVRQSTFIKEAPSPTLRRKLEESASFESLSPSS-----RPASPTRSQAQTPVL 2484
             RS    LV +ST  + +PS T    L  S +  SLS  S      P SP  + +     
Sbjct: 2484 ARSTTSGLVGESTPSRLSPSSTETTTLPGSPTTPSLSEKSTTFYTSPRSPDATLSPATTT 2543

Query: 2485 SPSLPDMSLSTHSSVQAGGWRKLPPNLSPTIEYNDG--RPAKRHDIARSHSESPSR---- 2538
            S  + + S ++HS           P  + T  + D    P        SHS   S     
Sbjct: 2544 SSGVSEESSTSHSQ----------PGSTHTTAFPDSTTTPGLSRHSTTSHSSPGSTDTTL 2593

Query: 2539 LPINRSGTWKREHSKHSSSLPRVSTWRRTGSSSSILSASSESSEKAKSEDEKHV------ 2592
            LP + + +   + S  S S P  +    +  S++ LS   ES+    S    H       
Sbjct: 2594 LPASTTTSGPSQESTTSHSSPGSTDTALSPGSTTALSFGQESTTFHSSPGSTHTTLFPDS 2653

Query: 2593 NSISGTKQSKENQVSAKGTWRKIKENEFSPTNSTSQTVSSGATNGAESKTLIYQMAPAVS 2652
             + SG  ++     S+ G+ R       SP +STS         G + ++  +Q  PA +
Sbjct: 2654 TTSSGIVEASTRVHSSTGSPR----TTLSPASSTSP--------GLQGESTTFQTHPAST 2701

Query: 2653 KTEDVWVRIEDCPINNPRSGRSPTGNTP-----------------------PVIDSVSEK 2689
             T          P+    +     G+TP                       P     +  
Sbjct: 2702 HTTPSPPSTATAPVEESTTYHRSPGSTPTTHFPASSTTSGHSEKSTIFHSSPDASGTTPS 2761

Query: 2690 ANPNIKDSKDNQAKQNVGNGSVPMRTV-------GLENRLNSFIQVDAPDQKGTEIKPGQ 2742
            +  +    +       +  GS  + T+       GL     +F    +P    T + P  
Sbjct: 2762 SAHSTTSGRGESTTSRISPGSTEITTLPGSTTTPGLSEASTTF--YSSPRSPTTTLSPAS 2819

Query: 2743 NNPVPVSETNESSIVE-------------RTP-FSSSSSSKHSSPSGTVAARVTPFNYNP 2788
               + V E + +S  +              TP  S  S++ +SS  G+    V P +   
Sbjct: 2820 MTSLGVGEESTTSRSQPGSTHSTVSPASTTTPGLSEESTTVYSSSPGSTETTVFPRSTTT 2879

Query: 2789 SPRKSSADSTSARPSQIPTPVNNNTKKRDSKTDSTESSGTQSPKRHSGS 2837
            S R     +  +RP+   T +           DST S  T+      GS
Sbjct: 2880 SVRGEEPTTFHSRPASTHTTLFTE--------DSTTSGLTEESTAFPGS 2920



 Score = 57.4 bits (137), Expect = 2e-07
 Identities = 135/647 (20%), Positives = 228/647 (35%), Gaps = 80/647 (12%)

Query: 2224 ISRGRT-MIHIPGVRNSSSSTSPVSKKGPPL-KTPASKSPSEGQTATTSPRGAKPSVKSE 2281
            IS G T    +PG    S++T+ +S+K      +P S   +    +TTS   ++ S  S 
Sbjct: 1668 ISSGSTETTALPG----STTTAGLSEKSTTFYSSPRSPDTTLSPASTTSSGVSEESTTSH 1723

Query: 2282 LSPVARQTSQIGGSSKAPSRSGSRDSTPSRPAQQPLSRPIQSPGRNSISPGRNGI--SPP 2339
              P +  T+   GS+  P  S    ++ S P     +    S   +S+ P       SP 
Sbjct: 1724 SRPGSTHTTAFPGSTTMPGVSQESTASHSSPGSTDTTLSPGSTTASSLGPESTTFHSSPG 1783

Query: 2340 NKLSQLPRTSSPSTASTKSSGSGKMSYTSPGRQMSQQNLTKQTGLSKNASSIPRSE---- 2395
            +  + L   ++ ++   ++S     S  SP   +S    T + G S    S P S+    
Sbjct: 1784 STETTLLPDNTTASGLLEASTPVHSSTGSPHTTLSPAGSTTRQGESTTFQSWPSSKDTMP 1843

Query: 2396 ------SASKGLNQMNNGNGANKKVELSRMSSTKSSGSESD-----------------RS 2432
                  SA   L+  ++G+ ++        SST    SE                   RS
Sbjct: 1844 APPTTTSAFVELSTTSHGSPSSTPTTHFSASSTTLGRSEESTTVHSSPVATATTPSPARS 1903

Query: 2433 ERPVLVRQSTFIKEAPSPTLRRKLEESASFESLSPSSRP--ASPTRSQAQTPVLSPSLPD 2490
                LV +ST    +P  T      ES++    S  SR   +S T + +  P  + +L +
Sbjct: 1904 TTSGLVEESTAYHSSPGSTQTMHFPESSTASGRSEESRTSHSSTTHTISSPPSTTSALVE 1963

Query: 2491 MSLSTHSSVQAGGWRKLPPNLSPTIEYNDGRPAKRHDIARSHSESPSRLPINRSGTWKRE 2550
               S HSS          P  + T  + D          RS   + S    + +GT    
Sbjct: 1964 EPTSYHSS----------PGSTATTHFPDSSTTS----GRSEESTASHSSQDATGTIVLP 2009

Query: 2551 HSKHSSSLPRVSTWRRTGSSSSILSASSESSEKAKSEDEKHVNSISGTKQSKENQVSAKG 2610
                +S L   ST      +S I S S E++    S     ++  S T  S     +   
Sbjct: 2010 ARSTTSVLLGEST------TSPISSGSMETTALPGSTTTPGLSEKSTTFHSSPRSPA--- 2060

Query: 2611 TWRKIKENEFSPTNSTSQTVSSGATNGAESKTLIYQMAPAVSKTEDVWVRIEDCPINNPR 2670
                      SP ++TS  VS  +T         +  A   S T     R      ++  
Sbjct: 2061 -------TTLSPASTTSSGVSEESTTSHSRPGSTHTTAFPDSTTTPGLSR------HSTT 2107

Query: 2671 SGRSPTGNTPPVIDSVSEKANPNIKDSKDNQAKQNVGNGSVPMRTVGLENRLNSFIQVDA 2730
            S  SP      ++ + +  + P+ + +  + +  +      P  T  L     S     +
Sbjct: 2108 SHSSPGSTDTTLLPASTTTSGPSQESTTSHSSPGSTDTALSPGSTTALSFGQESTTFHSS 2167

Query: 2731 PDQKGTEIKPGQNNPVPVSETNESSIVERTPFSSSSSSKHSSPSGTVAARVTPFNYNPSP 2790
            P    T + P       + E + + +   T    ++ S  SS S  +    T F  +P  
Sbjct: 2168 PGSTHTTLFPDSTTSSGIVEAS-TRVHSSTGSPRTTLSPASSTSPGLQGESTAFQTHP-- 2224

Query: 2791 RKSSADSTSARPSQIPTPVNNNT--KKRDSKTDSTESSGTQSPKRHS 2835
              +S  +T + PS    PV  +T   +    T +T    + +   HS
Sbjct: 2225 --ASTHTTPSPPSTATAPVEESTTYHRSPGSTPTTHFPASSTTSGHS 2269



 Score = 57.0 bits (136), Expect = 3e-07
 Identities = 129/621 (20%), Positives = 226/621 (36%), Gaps = 63/621 (10%)

Query: 2241 SSTSPVSKKGPPLKTPASKSPSEGQTATTSPRGAKPSVKSELSPVARQTSQIGGSSKAPS 2300
            S+T P S      K   ++S + G    ++P        S LSP + +T+ + GS   PS
Sbjct: 4024 STTFPSSSGSTGTKLSPARSTTSGLVGESTP--------SRLSPSSTETTTLPGSPTTPS 4075

Query: 2301 RSG----------SRDSTPSRPAQQPLSRPIQSPGRNSISPGRNGISP------PNKLSQ 2344
             S           S D+T S PA    S   +    +   PG    +        + LSQ
Sbjct: 4076 LSEKSTTFYTSPRSPDATLS-PATTTSSGVSEESSTSHSQPGSTHTTAFPDSTTTSGLSQ 4134

Query: 2345 LPRTSSPSTASTKSSGSGKMSYTSPGRQMSQQNLTKQTGLSKNASSIPRSESASKGLNQM 2404
             P TS  S  ST+++ S   +  S    + QQ+ T  +      +++   ++ + GL + 
Sbjct: 4135 EPTTSHSSQGSTEATLSPGSTTAS---SLGQQSTTFHSSPGDTETTLLPDDTITSGLVEA 4191

Query: 2405 NNGNGANKKVELSRMSSTKSSGSESDRSERPVLVRQSTFIKEAPSP--TLRRKLEESASF 2462
            +    ++    L    +  SS S   + E        +     PSP  T    +E S ++
Sbjct: 4192 STPTHSSTG-SLHTTLTPASSTSTGLQEESTTFQSWPSSSDTTPSPPSTTAVPVEVSTTY 4250

Query: 2463 ESLSPSSRPASPTRSQAQTPVLSPSLPDMSLSTHSSVQAGGWRKLPPNLSPTIEYNDGRP 2522
             S  PSS P   T   A +  L  S  + S + HSS  A G    P   + ++   +   
Sbjct: 4251 HS-RPSSTPT--THFSASSTTLGRS--EESTTVHSSPGATGTALFPTRSATSVLVGEPTT 4305

Query: 2523 AKRHDIARSHSESPSRLPINRSGTWKREHSKHSSSLPRVSTWRRTGSSSSILSASSESSE 2582
            +       S S   + LP + +     E S    S PR      + +S++    S ES+ 
Sbjct: 4306 SP----ISSGSTETTALPGSTTTAGLSEKSTTFYSSPRSPDTTLSPASTTSSGVSEESTT 4361

Query: 2583 KAKSEDEKHVNSI--SGTKQSKENQVSAKGTWRKIKENEFSPTNSTSQTVSSGATN---- 2636
                    H  +   S T      + +A  +     +   SP ++T+ ++   +T     
Sbjct: 4362 SHSRPGSMHTTAFPSSTTMPGVSQESTASHSSPGSTDTTLSPGSTTASSLGPESTTFHSS 4421

Query: 2637 -GAESKTLIYQMAPAVSKTEDVWVRIEDCPINN----PRSGRSPTGNTPPVIDSVSEKAN 2691
             G+   TL+     A    E         P+++    P +  SP G+T    +S + ++ 
Sbjct: 4422 PGSTETTLLPDNTTASGLLE------ASTPVHSSTGSPHTTLSPAGSTTRQGESTTFQSW 4475

Query: 2692 PNIKDSKDNQAKQNVGNGSVPMRTVGLENRLNS----FIQVDAPDQKGTEIKPGQNNPVP 2747
            PN KD+    A     +  V + T    +  ++    F        +  E     ++PV 
Sbjct: 4476 PNSKDT--TPAPPTTTSAFVELSTTSHGSPSSTPTTHFSASSTTLGRSEESTTVHSSPVA 4533

Query: 2748 VSETNESSIVERTPFSSSSSSKHSSPSGTVAARVTPFNYNPSPRKSSADSTSARPSQIPT 2807
             + T   +    +     S++ HSSP  T        N      + S  S S+    I +
Sbjct: 4534 TATTPSPARSTTSGLVEESTTYHSSPGSTQTMHFPESNTTSGRGEESTTSHSSTTHTISS 4593

Query: 2808 PVNNNTKKRDSKTDSTESSGT 2828
              +  +   +  T    S G+
Sbjct: 4594 APSTTSALVEEPTSYHSSPGS 4614



 Score = 53.9 bits (128), Expect = 2e-06
 Identities = 132/646 (20%), Positives = 224/646 (34%), Gaps = 56/646 (8%)

Query: 2224 ISRGRT-MIHIPGVRNSSSSTSPVSKKGPPL-KTPASKSPSEGQTATTSPRGAKPSVKSE 2281
            IS G T    +PG    S++T+ +S+K      +P S   +    +TTS   ++ S  S 
Sbjct: 3225 ISSGSTETTALPG----STTTAGLSEKSTTFYSSPRSPDTTLSPASTTSSGVSEESTTSH 3280

Query: 2282 LSPVARQTSQIGGSSKAPSRSGSRDSTPSRPAQQPLSRPIQSPGRNSISPGRNGI--SPP 2339
              P +  T+   GS+  P  S    ++ S P     +    S   +S+ P        P 
Sbjct: 3281 SRPGSTHTTAFPGSTTMPGVSQESTASHSSPGSTDTTLSPGSTTASSLGPESTTFHSGPG 3340

Query: 2340 NKLSQLPRTSSPSTASTKSSGSGKMSYTSPGRQMSQQNLTKQTGLSKNASSIPRSE---- 2395
            +  + L   ++ ++   ++S     S  SP   +S    T + G S    S P S+    
Sbjct: 3341 STETTLLPDNTTASGLLEASTPVHSSTGSPHTTLSPAGSTTRQGESTTFQSWPNSKDTTP 3400

Query: 2396 ------SASKGLNQMNNGNGANKKVELSRMSSTKSSGSESDRSERPVLVRQSTFIKEAPS 2449
                  SA   L+  ++G+ ++        SST    SE   +     V  +T     PS
Sbjct: 3401 APPTTTSAFVELSTTSHGSPSSTPTTHFSASSTTLGRSEESTTVHSSPVATAT----TPS 3456

Query: 2450 P---TLRRKLEESASFESLSPSSRPASPTRSQAQTPVLSPSLPDMSLSTHSSVQAGGWRK 2506
            P   T    +EES ++ S   S++      S   +     S    S +TH+   A     
Sbjct: 3457 PARSTTSGLVEESTTYHSSPGSTQTMHFPESDTTSGRGEESTTSHSSTTHTISSA----- 3511

Query: 2507 LPPNLSPTIEYNDGRPAKRHDIARSHSESPSRLPINRSGTWKREHSKHSSSLPRVSTWRR 2566
             P   S  +E      +     A +H    S      SG  +   + HSS     +    
Sbjct: 3512 -PSTTSALVEEPTSYHSSPGSTATTHFPDSS----TTSGRSEESTASHSSQDATGTIVLP 3566

Query: 2567 TGSSSSILSASSESSEKAKSEDEKHVNSISGTKQSKENQVSAKGTWRKIKENEFSPTNST 2626
              S++S+L   S +S  +    E      S T      + +   +  +      SP ++T
Sbjct: 3567 ARSTTSVLLGESTTSPISSGSMETTALPGSTTTPGLSEKSTTFHSSPRSPATTLSPASTT 3626

Query: 2627 SQTVSSGATNGAESKTLIYQMAPAVSKTEDVWVRIEDCPINNPRSGRSPTGNTPPVIDSV 2686
            S  VS  +T         +  A   S T     R      ++P  G + T   P    + 
Sbjct: 3627 SSGVSEESTTSHSRPGSTHTTAFPDSTTTPGLSRHSTTSHSSP--GSTDTTLLPASTTTS 3684

Query: 2687 SEKANPNIKDSKDNQAKQNVGNGSVPMRTVGLEN--------RLNSFIQVDAPDQKG--- 2735
                      S        +  GS    + G E+          ++ +  D+    G   
Sbjct: 3685 GSSQESTTSHSSSGSTDTALSPGSTTALSFGQESTTFHSSPGSTHTTLFPDSTTSSGIVE 3744

Query: 2736 --TEIKPGQNNP----VPVSETNESSIVERTPFSSSSSSKHSSPSGTVAARVTPFNYNPS 2789
              T +     +P     P S T+     E T F +  +S H++PS    A          
Sbjct: 3745 ASTRVHSSTGSPRTTLSPASSTSPGLQGESTAFQTHPASTHTTPSPPSTATAPVEESTTY 3804

Query: 2790 PRKSSADSTSARPSQIPTPVNNNTKKRDSKTDSTESSGTQSPKRHS 2835
             R   +  T+  P+   T  + +++K      S ++SGT     HS
Sbjct: 3805 HRSPGSTPTTHFPASSTT--SGHSEKSTIFHSSPDASGTTPSSAHS 3848



 Score = 48.5 bits (114), Expect = 9e-05
 Identities = 132/631 (20%), Positives = 221/631 (35%), Gaps = 81/631 (12%)

Query: 2223 SISRGRTMIHIPGVRNSSS-STSPVSKKGPPLKTPASKSPSEGQTATTSPRGAKPSVKSE 2281
            S  R     H+P    SS  S    +    P  T  +  P     +TT P  ++ S  S 
Sbjct: 641  SSPRSPDTTHLPASMTSSGVSEESTTSHSRPGSTHTTAFPG----STTMPGLSQESTASH 696

Query: 2282 LSPVARQTSQIGGSSKAPSRSGSRDSTPSRPAQQPLSRPIQSPGRNSISPGRNGISPPNK 2341
             SP    T+   GS+ A S      +  SRP     +     P   + S       P + 
Sbjct: 697  SSPGPTDTTLSPGSTTASSLGPEYTTFHSRPGS---TETTLLPDNTTASGLLEASMPVHS 753

Query: 2342 LSQLPRTSSPSTASTKSSGSGKMSYTSPGRQ--------MSQQNLTKQTGLSKNASSIP- 2392
             ++ P T+     ST   G     ++ P  +         +   +   T    + SSIP 
Sbjct: 754  STRSPHTTLSPAGSTTRQGESTTFHSWPSSKDTRPAPPTTTSAFVEPSTTSHGSPSSIPT 813

Query: 2393 ---RSESASKGL----NQMNNGNGANKKVELSRMSSTKSSGSESDRSERPVLVRQSTFIK 2445
                + S + GL       ++  G+ + +      +T   G ES  S        +  I 
Sbjct: 814  THISARSTTSGLVEESTTYHSSPGSTQTMHFPESDTTSGRGEESTTSHSST----THTIS 869

Query: 2446 EAPSPTLRRKLEESASFESLSPSSRPASPTRSQAQTPVLSPSLPDMSLSTHSSVQAGGWR 2505
             APS T    +EE  S+ S SP S   +     + T   S    + S ++HSS  A G  
Sbjct: 870  SAPS-TTSALVEEPTSYHS-SPGSTATTHFPDSSTTSGRS----EESTASHSSQDATGTI 923

Query: 2506 KLPPNLSPTIEYNDGRPAKRHDIARSHSESPSRLPINRSGTWKREHSKHSSSLPRVSTWR 2565
             LP   + ++   +   +       S S   + LP + +     E S    S PR     
Sbjct: 924  VLPARSTTSVLLGESTTSP----ISSGSMETTALPGSTTTPGLSERSTTFHSSPR----- 974

Query: 2566 RTGSSSSILSASSESSEKAKSEDEKHVNSISGTKQSKENQVSAKGTWRKIKENEFSPTNS 2625
               S ++ LS +S +S              SG  +      S  G+       + + T  
Sbjct: 975  ---SPATTLSPASTTS--------------SGVSEESTTSRSRPGSTHTTAFPDSTTTPG 1017

Query: 2626 TSQ-TVSSGATNGAESKTLIYQMAPAVSKTEDVWVRIEDCPINNPRSGRSPTGNTPPVID 2684
             S+ + +S ++ G+   TL+    PA + T          P     +  S +G+T   + 
Sbjct: 1018 LSRHSTTSHSSPGSTDTTLL----PASTTTSG--------PSQESTTSHSSSGSTDTALS 1065

Query: 2685 SVSEKANPNIKDSKDNQAKQNVGNGSVPMRTVGLENRLNSFIQVDAPDQKGTEIKPGQNN 2744
              S  A      S   ++     N      T+  ++  +S I V+A  +  +     +  
Sbjct: 1066 PGSTTAL-----SFGQESTTFHSNPGSTHTTLFPDSTTSSGI-VEASTRVHSSTGSPRTT 1119

Query: 2745 PVPVSETNESSIVERTPFSSSSSSKHSSPSGTVAARVTPFNYNPSPRKSSADSTSARPSQ 2804
              P S T+     E T F +  +S H++PS    A           R   +  T+  P+ 
Sbjct: 1120 LSPASSTSPGLQGESTAFQTHPASTHTTPSPPSTATAPVEESTTYHRSPGSTPTTHFPAS 1179

Query: 2805 IPTPVNNNTKKRDSKTDSTESSGTQSPKRHS 2835
              T  + +++K      S ++SGT     HS
Sbjct: 1180 STT--SGHSEKSTIFHSSPDASGTTPSSAHS 1208



 Score = 48.5 bits (114), Expect = 9e-05
 Identities = 137/654 (20%), Positives = 234/654 (35%), Gaps = 117/654 (17%)

Query: 2239 SSSSTSPVSKKGPPLKT-PASKSPSEGQTATTSPRGAKPSVKSELSPVARQTSQIGGSSK 2297
            +S+++S VS++     + P S   +   ++TT P  ++ S  S  SP +  T+   GS+ 
Sbjct: 4348 ASTTSSGVSEESTTSHSRPGSMHTTAFPSSTTMPGVSQESTASHSSPGSTDTTLSPGSTT 4407

Query: 2298 APSRSGSRDSTPSRP-------------------AQQPLSRPIQSPGRNSISPG----RN 2334
            A S      +  S P                   A  P+     SP   ++SP     R 
Sbjct: 4408 ASSLGPESTTFHSSPGSTETTLLPDNTTASGLLEASTPVHSSTGSP-HTTLSPAGSTTRQ 4466

Query: 2335 GIS---------------PPNKLSQLPRTSSPSTASTKSSGSGKMSYTSPGRQMSQQNLT 2379
            G S               PP   S     S+ S  S  S+ +   S +S     S+++ T
Sbjct: 4467 GESTTFQSWPNSKDTTPAPPTTTSAFVELSTTSHGSPSSTPTTHFSASSTTLGRSEESTT 4526

Query: 2380 KQTGLSKNASSIPRSESASKGL----NQMNNGNGANKKVELSRMSSTKSSGSESDRSERP 2435
              +     A++   + S + GL       ++  G+ + +     ++T   G ES  S   
Sbjct: 4527 VHSSPVATATTPSPARSTTSGLVEESTTYHSSPGSTQTMHFPESNTTSGRGEESTTSHSS 4586

Query: 2436 VLVRQSTFIKEAPSPTLRRKLEESASFESLSPSSRPASPTRSQAQTPVLSPSLPDMSLST 2495
                 +  I  APS T    +EE  S+ S SP S   +     + T   S    + S ++
Sbjct: 4587 T----THTISSAPS-TTSALVEEPTSYHS-SPGSTATTHFPDSSTTSGRS----EESTAS 4636

Query: 2496 HSSVQAGGWRKLPPNLSPTIEYNDGRPAKRHDIARSHSESPSRLPINRSGTWKREHSKHS 2555
            HSS  A G   LP   + ++   +   +       S S   + LP + +     E S   
Sbjct: 4637 HSSQDATGTIVLPARSTTSVLLGESTTSP----ISSGSMETTALPGSTTTPGLSEKSTTF 4692

Query: 2556 SSLPRVSTWRRTGSSSSILSASSESSEKAKS-------------------EDEKHVNSIS 2596
             S P  +      +SS+ L  S ES+    S                   E+    +S  
Sbjct: 4693 HSSPSSTPTTHFSASSTTLGRSEESTTVHSSPVATATTPSPARSTTSGLVEESTAYHSSP 4752

Query: 2597 GTKQSKENQVSAKGTWRKIKENEFSPTNSTSQTVSS--GATNGAESKTLIYQMAPAVSKT 2654
            G+ Q+     S+  + R   E   +  +ST+ T+SS    T+    +   Y  +P    T
Sbjct: 4753 GSTQTMHFPESSTASGR--SEESRTSHSSTTHTISSPPSTTSALVEEPTSYHSSPGSIAT 4810

Query: 2655 EDVWVRIEDCPINNPRSGRSPTGNTPPVIDSVSEKANPNIKDSKDNQAKQNVGNGSVPMR 2714
                      P ++  SGRS         +S +  ++P+        A     +G +   
Sbjct: 4811 THF-------PESSTTSGRSE--------ESTASHSSPDTNGITPLPAHFTT-SGRIAES 4854

Query: 2715 TV------GLENRLNSFIQVDAPDQKGTEIKPGQNNP----VPVSETNESSIVERTPFSS 2764
            T        +E  L S         K T +     +P     P S T+ S   E T   S
Sbjct: 4855 TTFYISPGSMETTLASTATTPGLSAKSTILYSSSRSPDQTLSPASMTSSSISGEPTSLYS 4914

Query: 2765 SSSSKHSS--PSGTVAARV----TPFNYNPSPRKSSAD----STSARPSQIPTP 2808
             + S H++  P+ T  + +    T F+  P   +++      +TS+   +  TP
Sbjct: 4915 QAESTHTTAFPASTTTSGLSQESTTFHSKPGSTETTLSPGSITTSSFAQEFTTP 4968



 Score = 47.4 bits (111), Expect = 2e-04
 Identities = 156/729 (21%), Positives = 256/729 (35%), Gaps = 128/729 (17%)

Query: 2197 SLITGKVRSNSEISGQMKQ---PLQANMPSISRGRTMIHIPGVRNSSSSTSPVSKKGPPL 2253
            S++ G+  ++   SG M+    P     P +S   T  H       SS  SP +      
Sbjct: 932  SVLLGESTTSPISSGSMETTALPGSTTTPGLSERSTTFH-------SSPRSPATTL---- 980

Query: 2254 KTPASKSPSEGQTATTSPRGAKPSVKSELSPVARQTSQIGGSSKAPSRSGSRDSTPSRPA 2313
             +PAS + S     +T+ R    S  +   P +  T  +   S     S     T   PA
Sbjct: 981  -SPASTTSSGVSEESTTSRSRPGSTHTTAFPDSTTTPGLSRHSTTSHSSPGSTDTTLLPA 1039

Query: 2314 QQPLSRPIQ-------SPGR--NSISPG---------------RNGISPPNKLSQLPRTS 2349
                S P Q       S G    ++SPG                N  S    L     TS
Sbjct: 1040 STTTSGPSQESTTSHSSSGSTDTALSPGSTTALSFGQESTTFHSNPGSTHTTLFPDSTTS 1099

Query: 2350 S----PSTASTKSSGSGK-----MSYTSPGRQ------MSQQNLTKQTGLSKNASSIPRS 2394
            S     ST    S+GS +      S TSPG Q       +    T  T    + ++ P  
Sbjct: 1100 SGIVEASTRVHSSTGSPRTTLSPASSTSPGLQGESTAFQTHPASTHTTPSPPSTATAPVE 1159

Query: 2395 ESA----------SKGLNQMNNGNGANKKVELSRMSSTKSSGSESDRSERPVLVRQSTFI 2444
            ES           +      +  +G ++K  +   S   S  + S          +ST  
Sbjct: 1160 ESTTYHRSPGSTPTTHFPASSTTSGHSEKSTIFHSSPDASGTTPSSAHSTTSGRGESTTS 1219

Query: 2445 KEAPSPTLRRKLEESASFESLSPS-----SRPASPTRSQAQTPVLSPSLPDMSL------ 2493
            + +P  T    L  S +   LS +     S P SPT + +   + S  + + S       
Sbjct: 1220 RISPGSTEITTLPGSTTTPGLSEASTTFYSSPRSPTTTLSPASMTSLGVGEESTTSRSQP 1279

Query: 2494 -STHSSVQAGGWRKLPPNLSPTIEYNDGRPAKR-----HDIARS-HSESPSRL---PINR 2543
             STHS+V          +   T  Y+  R +       H    S H E P+     P + 
Sbjct: 1280 GSTHSTVSPASTTTPGLSEESTTVYSSSRGSTETTVFPHSTTTSVHGEEPTTFHSRPAST 1339

Query: 2544 SGTWKREHS------KHSSSLPRVSTWRRTGSSSSILSAS-SESSEKAKSEDEKHVNSIS 2596
              T   E S      + S++ P      +TG  +++ +A   E S    S      +  +
Sbjct: 1340 HTTLFTEDSTTSGLTEESTAFPGSPASTQTGLPATLTTADLGEESTTFPSS-----SGST 1394

Query: 2597 GTKQSKENQVSAKGTWRKIKENEFSPTNSTSQTVSSGATNG--AESKTLIY--------Q 2646
            GTK S     ++ G   +   +  SP+++ + T+    T    +E  T  Y         
Sbjct: 1395 GTKLSPARSTTS-GLVGESTPSRLSPSSTETTTLPGSPTTPSLSEKSTTFYTSPRSPDAT 1453

Query: 2647 MAPAVSKTEDVWVRIEDCPINNPRSGRSPTGNTPPVIDSVSEKANPNIKDSKDNQAKQNV 2706
            ++PA + +  V    E+   ++ + G + T   P    +      P    S     +  +
Sbjct: 1454 LSPATTTSSGV---SEESSTSHSQPGSTHTTAFPDSTTTSDLSQEPTTSHSSQGSTEATL 1510

Query: 2707 GNGSVPMRTVGLENRLNSFIQVDAPDQKGTEIKPGQNNPVPVSETNESSIVE-RTPFSSS 2765
              GS    ++G +    S     +P    T + P         +T  S +VE  TP  SS
Sbjct: 1511 SPGSTTASSLGQQ----STTFHSSPGDTETTLLP--------DDTITSGLVEASTPTHSS 1558

Query: 2766 SSSKHS--SPSGTVAARVTPFNYNPSPRKSSADSTSARPSQIPTPVNNNT--KKRDSKTD 2821
            + S H+  +P+ + +A +   +       SS+D+T + P     PV  +T    R S T 
Sbjct: 1559 TGSLHTTLTPASSTSAGLQEESTTFQSWPSSSDTTPSPPGTTAAPVEVSTTYHSRPSSTP 1618

Query: 2822 STESSGTQS 2830
            +T  S + +
Sbjct: 1619 TTHFSASST 1627



 Score = 43.1 bits (100), Expect = 0.004
 Identities = 137/660 (20%), Positives = 232/660 (35%), Gaps = 117/660 (17%)

Query: 2197 SLITGKVRSNSEISGQMKQ---PLQANMPSISRGRTMIHIPGVRNSSSSTSPVSKKGPPL 2253
            S++ G+  ++   SG M+    P     P +S   T  H       SS  SP +   P  
Sbjct: 2015 SVLLGESTTSPISSGSMETTALPGSTTTPGLSEKSTTFH-------SSPRSPATTLSPAS 2067

Query: 2254 KTPASKSPSEGQTATTSPRGAKPSVKSELSPVARQTSQIGGSSKAPSRSGSRDSTPSRPA 2313
             T  S   SE  T + S  G   S  +   P +  T  +   S     S     T   PA
Sbjct: 2068 TT--SSGVSEESTTSHSRPG---STHTTAFPDSTTTPGLSRHSTTSHSSPGSTDTTLLPA 2122

Query: 2314 QQPLSRPIQSPGRNSISPGRNGISPPNKLSQLPRTSSPSTASTKSSGSGKMSY-TSPGRQ 2372
                S P Q    +  SPG    +            SP + +  S G    ++ +SPG  
Sbjct: 2123 STTTSGPSQESTTSHSSPGSTDTA-----------LSPGSTTALSFGQESTTFHSSPG-- 2169

Query: 2373 MSQQNLTKQTGLSKNASSIPRSESAS---KGLNQMNNGNGANKKVELSRMSSTKS--SGS 2427
                        S + +  P S ++S   +   ++++  G + +  LS  SST     G 
Sbjct: 2170 ------------STHTTLFPDSTTSSGIVEASTRVHSSTG-SPRTTLSPASSTSPGLQGE 2216

Query: 2428 ESDRSERPVLVRQSTFIKEAPSPTLRRKLEESASFESLSPSSRP------ASPTRSQAQT 2481
             +     P     ST    +P  T    +EES ++   SP S P      +S T   ++ 
Sbjct: 2217 STAFQTHPA----STHTTPSPPSTATAPVEESTTYHR-SPGSTPTTHFPASSTTSGHSEK 2271

Query: 2482 PVLSPSLPDMSLSTHSSVQ---AGGWRKLPPNLSP------TIEYNDGRP----AKRHDI 2528
              +  S PD S +T SS     +G        +SP      T+  +   P    A     
Sbjct: 2272 STIFHSSPDASGTTPSSAHSTTSGRGESTTSRISPGSTEITTLPGSTTTPGLSEASTTFY 2331

Query: 2529 ARSHSESPSRLPINRSGTWKREHSKHSSSLPRVSTWRRTGSSSSILSASSESSEKAKSED 2588
            +   S + +  P + +     E S  S S P        GS+ S +S +S ++     E 
Sbjct: 2332 SSPRSPTTTLSPASMTSLGVGEESTTSRSQP--------GSTHSTVSPASTTTPGLSEES 2383

Query: 2589 EKHVNSISGTKQS----KENQVSAKGTWRKIKENEFSPTNSTSQTVSSGATNGAESKTLI 2644
                +S  G+ ++    +    S +G       +  + T++T  T  S  T+G   ++  
Sbjct: 2384 TTVYSSSPGSTETTVFPRTPTTSVRGEEPTTFHSRPASTHTTLFTEDS-TTSGLTEESTA 2442

Query: 2645 YQMAPAVSK--------TEDVWVRIEDCPINNPRSGR--SPTGNTPPVIDSVSEKANPNI 2694
            +  +PA ++        T D+       P ++  +G   SP  +T      +  ++ P+ 
Sbjct: 2443 FPGSPASTQTGLPATLTTADLGEESTTFPSSSGSTGTTLSPARST---TSGLVGESTPSR 2499

Query: 2695 KDSKDNQAKQNVGNGSVPMRTVGLENRLNSFIQVDAPDQKGTEIKPGQNNPVPVSETNES 2754
                  +     G+ + P     L  +  +F    +P      + P       VSE + +
Sbjct: 2500 LSPSSTETTTLPGSPTTP----SLSEKSTTF--YTSPRSPDATLSPATTTSSGVSEESST 2553

Query: 2755 SIVE-------------RTP-FSSSSSSKHSSPSGTVAARVTPFNYNPSPRKSSADSTSA 2800
            S  +              TP  S  S++ HSSP  T    +        P + S  S S+
Sbjct: 2554 SHSQPGSTHTTAFPDSTTTPGLSRHSTTSHSSPGSTDTTLLPASTTTSGPSQESTTSHSS 2613



 Score = 41.6 bits (96), Expect = 0.011
 Identities = 74/358 (20%), Positives = 126/358 (35%), Gaps = 26/358 (7%)

Query: 1176 PIDYSLKYATDIPSSQKQSFSFSKSSSGQSSKTEHMSSSSENTSTPSSNAKRQNQLHPSS 1235
            P++ S  Y     S+    F  S ++SG S K+    SS + + T  S+A         S
Sbjct: 3797 PVEESTTYHRSPGSTPTTHFPASSTTSGHSEKSTIFHSSPDASGTTPSSAHSTTSGRGES 3856

Query: 1236 AQSRSGQPQKAATCKVSS-----INQETIQTYCVEDTPICFSRCSSLSSLSSAED----- 1285
              SR        T    S     +++ +   Y    +P      +S++SL   E+     
Sbjct: 3857 TTSRISPGSTEITTLPGSTTTPGLSEASTTFYSSPRSPTTTLSPASMTSLGVGEESTTSR 3916

Query: 1286 -EIGCNQTTQEADSANTLQIAEIKEKIGTRSAEDPVSEVPAVSQHPRTKSSRLQGSSLSS 1344
             + G   +T    S  T  ++E  E     S+    +E     +   T   R + ++  S
Sbjct: 3917 SQPGSTHSTVSPASTTTPGLSE--ESTTVYSSSPGSTETTVFPRSTTTSVRREEPTTFHS 3974

Query: 1345 ESARHKAVEFSSGAKSPSKSGAQT--PKSPPEHYVQETPLMFSRCTSVSSLDSFESRSIA 1402
              A      F+  + +   +   T  P SP        P   +         +F S S +
Sbjct: 3975 RPASTHTTLFTEDSTTSGLTEESTAFPGSPASTQT-GLPATLTTADLGEESTTFPSSSGS 4033

Query: 1403 SSVQSEPCSGMVSGII---SPSDLPDSPGQTMPPSRSKTPPPPPQTAQTKREVPKNKAPT 1459
            +  +  P     SG++   +PS L  S  +T     S T P   + + T    P++   T
Sbjct: 4034 TGTKLSPARSTTSGLVGESTPSRLSPSSTETTTLPGSPTTPSLSEKSTTFYTSPRSPDAT 4093

Query: 1460 ---AEKRESGPKQAAVNAAVQ----RVQVLPDADTLLHFATESTPDGFSCSSSLSALS 1510
               A    SG  + +  +  Q         PD+ T    + E T    S  S+ + LS
Sbjct: 4094 LSPATTTSSGVSEESSTSHSQPGSTHTTAFPDSTTTSGLSQEPTTSHSSQGSTEATLS 4151



 Score = 40.8 bits (94), Expect = 0.019
 Identities = 74/360 (20%), Positives = 134/360 (37%), Gaps = 30/360 (8%)

Query: 1176 PIDYSLKYATDIPSSQKQSFSFSKSSSGQSSKTEHMSSSSENTSTPSSNAKRQNQLHPSS 1235
            P++ S  Y     S+    F  S ++SG S K+    SS + + T  S+A         S
Sbjct: 2714 PVEESTTYHRSPGSTPTTHFPASSTTSGHSEKSTIFHSSPDASGTTPSSAHSTTSGRGES 2773

Query: 1236 AQSRSGQPQKAATCKVSS-----INQETIQTYCVEDTPICFSRCSSLSSLSSAED----- 1285
              SR        T    S     +++ +   Y    +P      +S++SL   E+     
Sbjct: 2774 TTSRISPGSTEITTLPGSTTTPGLSEASTTFYSSPRSPTTTLSPASMTSLGVGEESTTSR 2833

Query: 1286 -EIGCNQTTQEADSANTLQIAEIKEKIGTRSAEDPVSEVPAVSQHPRTKSSRLQGSSLSS 1344
             + G   +T    S  T  ++E    + + S     + V      PR+ ++ ++G   ++
Sbjct: 2834 SQPGSTHSTVSPASTTTPGLSEESTTVYSSSPGSTETTV-----FPRSTTTSVRGEEPTT 2888

Query: 1345 ESARHKAVEFSSGAKSPSKSG--AQTPKSPPEHYVQETPLMFSRCTSVSSLDS--FESRS 1400
              +R  +   +   +  + SG   ++   P      +T L  +  T+    +S  F S S
Sbjct: 2889 FHSRPASTHTTLFTEDSTTSGLTEESTAFPGSPASTQTGLPATLTTADLGEESTTFPSSS 2948

Query: 1401 IASSVQSEPCSGMVSGII---SPSDLPDSPGQTMPPSRSKTPPPPPQTAQTKREVPKNKA 1457
             ++     P     SG++   +PS L  S  +T     S T P   + + T    P++  
Sbjct: 2949 GSTGTTLSPARSTTSGLVGESTPSRLSPSSTETTTLPGSPTTPSLSEKSTTFYTSPRSPD 3008

Query: 1458 PT---AEKRESGPKQAAVNAAVQ----RVQVLPDADTLLHFATESTPDGFSCSSSLSALS 1510
             T   A    SG  + +  +  Q         PD+ T    + E T    S  S+ + LS
Sbjct: 3009 ATLSPATTTSSGVSEESSTSHSQPGSTHTTAFPDSTTTSGLSQEPTASHSSQGSTEATLS 3068



 Score = 40.4 bits (93), Expect = 0.025
 Identities = 71/350 (20%), Positives = 129/350 (36%), Gaps = 25/350 (7%)

Query: 1176 PIDYSLKYATDIPSSQKQSFSFSKSSSGQSSKTEHMSSSSENTSTPSSNAKRQNQLHPSS 1235
            P++ S  Y     S+    F  S ++SG S K+    SS + + T  S+A         S
Sbjct: 2240 PVEESTTYHRSPGSTPTTHFPASSTTSGHSEKSTIFHSSPDASGTTPSSAHSTTSGRGES 2299

Query: 1236 AQSRSGQPQKAATCKVSS-----INQETIQTYCVEDTPICFSRCSSLSSLSSAED----- 1285
              SR        T    S     +++ +   Y    +P      +S++SL   E+     
Sbjct: 2300 TTSRISPGSTEITTLPGSTTTPGLSEASTTFYSSPRSPTTTLSPASMTSLGVGEESTTSR 2359

Query: 1286 -EIGCNQTTQEADSANTLQIAEIKEKIGTRSAEDPVSEVPAVSQHPRTKSSRLQGSSLSS 1344
             + G   +T    S  T  ++E    + + S     + V      PRT ++ ++G   ++
Sbjct: 2360 SQPGSTHSTVSPASTTTPGLSEESTTVYSSSPGSTETTV-----FPRTPTTSVRGEEPTT 2414

Query: 1345 ESARHKAVEFSSGAKSPSKSG--AQTPKSPPEHYVQETPLMFSRCTSVSSLDS--FESRS 1400
              +R  +   +   +  + SG   ++   P      +T L  +  T+    +S  F S S
Sbjct: 2415 FHSRPASTHTTLFTEDSTTSGLTEESTAFPGSPASTQTGLPATLTTADLGEESTTFPSSS 2474

Query: 1401 IASSVQSEPCSGMVSGII---SPSDLPDSPGQTMPPSRSKTPPPPPQTAQTKREVPKNKA 1457
             ++     P     SG++   +PS L  S  +T     S T P   + + T    P  ++
Sbjct: 2475 GSTGTTLSPARSTTSGLVGESTPSRLSPSSTETTTLPGSPTTPSLSEKSTTFYTSP--RS 2532

Query: 1458 PTAEKRESGPKQAAVNAAVQRVQVLPDADTLLHFATESTPDGFSCSSSLS 1507
            P A    +    + V+         P +     F   +T  G S  S+ S
Sbjct: 2533 PDATLSPATTTSSGVSEESSTSHSQPGSTHTTAFPDSTTTPGLSRHSTTS 2582



 Score = 39.7 bits (91), Expect = 0.043
 Identities = 73/360 (20%), Positives = 133/360 (36%), Gaps = 30/360 (8%)

Query: 1176 PIDYSLKYATDIPSSQKQSFSFSKSSSGQSSKTEHMSSSSENTSTPSSNAKRQNQLHPSS 1235
            P++ S  Y     S+    F  S ++SG S K+    SS + + T  S+A         S
Sbjct: 1157 PVEESTTYHRSPGSTPTTHFPASSTTSGHSEKSTIFHSSPDASGTTPSSAHSTTSGRGES 1216

Query: 1236 AQSRSGQPQKAATCKVSS-----INQETIQTYCVEDTPICFSRCSSLSSLSSAED----- 1285
              SR        T    S     +++ +   Y    +P      +S++SL   E+     
Sbjct: 1217 TTSRISPGSTEITTLPGSTTTPGLSEASTTFYSSPRSPTTTLSPASMTSLGVGEESTTSR 1276

Query: 1286 -EIGCNQTTQEADSANTLQIAEIKEKIGTRSAEDPVSEVPAVSQHPRTKSSRLQGSSLSS 1344
             + G   +T    S  T  ++E    + + S     + V      P + ++ + G   ++
Sbjct: 1277 SQPGSTHSTVSPASTTTPGLSEESTTVYSSSRGSTETTV-----FPHSTTTSVHGEEPTT 1331

Query: 1345 ESARHKAVEFSSGAKSPSKSG--AQTPKSPPEHYVQETPLMFSRCTSVSSLDS--FESRS 1400
              +R  +   +   +  + SG   ++   P      +T L  +  T+    +S  F S S
Sbjct: 1332 FHSRPASTHTTLFTEDSTTSGLTEESTAFPGSPASTQTGLPATLTTADLGEESTTFPSSS 1391

Query: 1401 IASSVQSEPCSGMVSGII---SPSDLPDSPGQTMPPSRSKTPPPPPQTAQTKREVPKNKA 1457
             ++  +  P     SG++   +PS L  S  +T     S T P   + + T    P++  
Sbjct: 1392 GSTGTKLSPARSTTSGLVGESTPSRLSPSSTETTTLPGSPTTPSLSEKSTTFYTSPRSPD 1451

Query: 1458 PT---AEKRESGPKQAAVNAAVQ----RVQVLPDADTLLHFATESTPDGFSCSSSLSALS 1510
             T   A    SG  + +  +  Q         PD+ T    + E T    S  S+ + LS
Sbjct: 1452 ATLSPATTTSSGVSEESSTSHSQPGSTHTTAFPDSTTTSDLSQEPTTSHSSQGSTEATLS 1511



 Score = 39.7 bits (91), Expect = 0.043
 Identities = 78/355 (21%), Positives = 131/355 (36%), Gaps = 56/355 (15%)

Query: 1189 SSQKQSFSFSKSSSGQSSKTEHMSSSSENTSTPSSNAKRQNQ------------------ 1230
            S+    FS S ++ G+S ++  + SS   T+T  S A+                      
Sbjct: 4505 STPTTHFSASSTTLGRSEESTTVHSSPVATATTPSPARSTTSGLVEESTTYHSSPGSTQT 4564

Query: 1231 LHPSSAQSRSGQPQKAATCKVSSINQETIQTYCVEDTPICFSRCSSLSSLSSAEDEIGCN 1290
            +H   + + SG+ +++ T   S+       T+ +   P   S  + +   +S     G  
Sbjct: 4565 MHFPESNTTSGRGEESTTSHSST-------THTISSAPSTTS--ALVEEPTSYHSSPGST 4615

Query: 1291 QTTQEADSANTLQIAEIKEKIGTRSAEDPVSEV--PAVSQHPRTKSSRLQGSS----LSS 1344
             TT   DS+ T   +E  E   + S++D    +  PA     R+ +S L G S    +SS
Sbjct: 4616 ATTHFPDSSTTSGRSE--ESTASHSSQDATGTIVLPA-----RSTTSVLLGESTTSPISS 4668

Query: 1345 ESARHKAVEFSS---GAKSPSKSGAQTPKSPPEHYVQETPLMFSRCTSVSSLDSFESRSI 1401
             S    A+  S+   G    S +   +P S P  +   +     R    +++    S  +
Sbjct: 4669 GSMETTALPGSTTTPGLSEKSTTFHSSPSSTPTTHFSASSTTLGRSEESTTV---HSSPV 4725

Query: 1402 ASSVQSEPCSGMVSGIISPSD-LPDSPGQTMPPSRSKTPPPPPQTAQTKREVPKNKAPTA 1460
            A++    P     SG++  S     SPG T          P   TA  + E  +    + 
Sbjct: 4726 ATATTPSPARSTTSGLVEESTAYHSSPGSTQTMHF-----PESSTASGRSEESRTSHSST 4780

Query: 1461 EKRESGPKQAAVNAAVQR---VQVLPDADTLLHFATESTPDGFSCSSSLSALSLD 1512
                S P  +  +A V+        P +    HF   ST  G S  S+ S  S D
Sbjct: 4781 THTISSP-PSTTSALVEEPTSYHSSPGSIATTHFPESSTTSGRSEESTASHSSPD 4834



 Score = 36.6 bits (83), Expect = 0.36
 Identities = 78/382 (20%), Positives = 134/382 (35%), Gaps = 56/382 (14%)

Query: 1177 IDYSLKYATDIPSSQKQSFSFSKSSSGQS--SKTEHMSSSSENTSTPSSNAKRQNQLHPS 1234
            ++ S  Y +   S+Q   F  S ++SG+S  S+T H S++   +S PS+ +    +  P+
Sbjct: 1909 VEESTAYHSSPGSTQTMHFPESSTASGRSEESRTSHSSTTHTISSPPSTTSALVEE--PT 1966

Query: 1235 SAQSRSGQ------PQKAATCKVSSINQETIQTYCVEDT------PICFSRCSSLSSLSS 1282
            S  S  G       P  + T   S  ++E+  ++  +D       P   +    L   ++
Sbjct: 1967 SYHSSPGSTATTHFPDSSTT---SGRSEESTASHSSQDATGTIVLPARSTTSVLLGESTT 2023

Query: 1283 AEDEIGCNQTTQEADSANTLQIAEIKEKIGTRSAEDPVSEVPA------VSQHPRTKSSR 1336
            +    G  +TT    S  T  ++E      +       +  PA      VS+   T  SR
Sbjct: 2024 SPISSGSMETTALPGSTTTPGLSEKSTTFHSSPRSPATTLSPASTTSSGVSEESTTSHSR 2083

Query: 1337 --------LQGSSLSSESARHKAVEFSSGAKS-------------PSKSGAQTPKSPPEH 1375
                       S+ +   +RH     SS   +             PS+    +  SP   
Sbjct: 2084 PGSTHTTAFPDSTTTPGLSRHSTTSHSSPGSTDTTLLPASTTTSGPSQESTTSHSSPGST 2143

Query: 1376 YVQETPLMFSRCTSVSSLDSFESRSIASSVQSEPCSGMVSGIISPS----DLPDSPGQTM 1431
                +P   +  +      +F S   ++     P S   SGI+  S        SP  T+
Sbjct: 2144 DTALSPGSTTALSFGQESTTFHSSPGSTHTTLFPDSTTSSGIVEASTRVHSSTGSPRTTL 2203

Query: 1432 PPSRSKTPP-PPPQTAQTKREVPKNKAPTAEKRESGPKQAAVNAAVQRVQVLPDADTLLH 1490
             P+ S +P      TA        +  P+     + P + +           P +    H
Sbjct: 2204 SPASSTSPGLQGESTAFQTHPASTHTTPSPPSTATAPVEESTT-----YHRSPGSTPTTH 2258

Query: 1491 FATESTPDGFSCSSSLSALSLD 1512
            F   ST  G S  S++   S D
Sbjct: 2259 FPASSTTSGHSEKSTIFHSSPD 2280



 Score = 35.4 bits (80), Expect = 0.81
 Identities = 61/272 (22%), Positives = 99/272 (36%), Gaps = 27/272 (9%)

Query: 1177 IDYSLKYATDIPSSQKQSFSFSKSSS--GQSSKTEHMSSSSENTSTPSSNAKRQNQLHPS 1234
            ++ S  Y +   S+Q   F  S ++S  G+ S T H S++   +S PS+ +    +  P+
Sbjct: 3466 VEESTTYHSSPGSTQTMHFPESDTTSGRGEESTTSHSSTTHTISSAPSTTSALVEE--PT 3523

Query: 1235 SAQSRSGQ------PQKAATCKVSSINQETIQTYCVEDT------PICFSRCSSLSSLSS 1282
            S  S  G       P  + T   S  ++E+  ++  +D       P   +    L   ++
Sbjct: 3524 SYHSSPGSTATTHFPDSSTT---SGRSEESTASHSSQDATGTIVLPARSTTSVLLGESTT 3580

Query: 1283 AEDEIGCNQTTQEADSANTLQIAEIKEKIGTRSAEDPVSEVPAVSQHPRTKSSRLQGSSL 1342
            +    G  +TT    S  T  ++E      T     P S    +S    T S   + S+ 
Sbjct: 3581 SPISSGSMETTALPGSTTTPGLSE----KSTTFHSSPRSPATTLSPASTTSSGVSEESTT 3636

Query: 1343 S-SESARHKAVEFSSGAKSPSKSGAQTPKSPPEHYVQETPLMFSRCTSVSSLDSFESRSI 1401
            S S         F     +P  S   T           T L  S  TS SS +S  S S 
Sbjct: 3637 SHSRPGSTHTTAFPDSTTTPGLSRHSTTSHSSPGSTDTTLLPASTTTSGSSQESTTSHSS 3696

Query: 1402 ASSVQSEPCSGMVSGII---SPSDLPDSPGQT 1430
            + S  +    G  + +      +    SPG T
Sbjct: 3697 SGSTDTALSPGSTTALSFGQESTTFHSSPGST 3728



 Score = 35.0 bits (79), Expect = 1.1
 Identities = 57/268 (21%), Positives = 104/268 (38%), Gaps = 26/268 (9%)

Query: 1177 IDYSLKYATDIPSSQKQSFSFSKSSS--GQSSKTEHMSSSSENTSTPSSNAKRQNQLHPS 1234
            ++ S  Y +   S+Q   F  S ++S  G+ S T H S++   +S PS+ +    +  P+
Sbjct: 4549 VEESTTYHSSPGSTQTMHFPESNTTSGRGEESTTSHSSTTHTISSAPSTTSALVEE--PT 4606

Query: 1235 SAQSRSGQ------PQKAATCKVSSINQETIQTYCVEDT------PICFSRCSSLSSLSS 1282
            S  S  G       P  + T   S  ++E+  ++  +D       P   +    L   ++
Sbjct: 4607 SYHSSPGSTATTHFPDSSTT---SGRSEESTASHSSQDATGTIVLPARSTTSVLLGESTT 4663

Query: 1283 AEDEIGCNQTTQEADSANTLQIAEIKEKIGTRSAEDPVSEVPAVSQ--HPRTKSSRLQGS 1340
            +    G  +TT    S  T  ++E      +  +  P +   A S       +S+ +  S
Sbjct: 4664 SPISSGSMETTALPGSTTTPGLSEKSTTFHSSPSSTPTTHFSASSTTLGRSEESTTVHSS 4723

Query: 1341 SLSSESARHKAVEFSSGAKSPSKSGAQTPKSPPEHYVQETPLMFSRCTSVSSLDSFESRS 1400
             +++ +    A   +SG    S +   +P S    +  E     S   S  S +S  S S
Sbjct: 4724 PVATATTPSPARSTTSGLVEESTAYHSSPGSTQTMHFPE-----SSTASGRSEESRTSHS 4778

Query: 1401 IASSVQSEPCSGMVSGIISPSDLPDSPG 1428
              +   S P S   + +  P+    SPG
Sbjct: 4779 STTHTISSPPSTTSALVEEPTSYHSSPG 4806



 Score = 34.3 bits (77), Expect = 1.8
 Identities = 59/282 (20%), Positives = 108/282 (38%), Gaps = 45/282 (15%)

Query: 1176 PIDYSLKYATDIPSSQKQSFSFSKSSSGQSSKTEHMSSSSENTST---PSSNAKRQNQLH 1232
            P++ S  Y +   S+    FS S ++ G+S ++  + SS   T T   P+ +A       
Sbjct: 3160 PVEVSTTYHSRPSSTPTTHFSASSTTLGRSEESTTVHSSPGATGTALFPTRSATSVLVGE 3219

Query: 1233 PSSAQSRSGQPQKAA---TCKVSSINQETIQTYCVEDTPICFSRCSSLSSLSSAEDEIGC 1289
            P+++   SG  +  A   +   + +++++   Y    +P      ++LS  S+    +  
Sbjct: 3220 PTTSPISSGSTETTALPGSTTTAGLSEKSTTFYSSPRSP-----DTTLSPASTTSSGVSE 3274

Query: 1290 NQTTQEADSANTLQIAEIKEKIGTRSAEDPVSEVPAVSQHPRTKSSRLQGSSLSSESARH 1349
              TT  +   +T   A      G+ +      E  A    P +  + L   S ++ S   
Sbjct: 3275 ESTTSHSRPGSTHTTA----FPGSTTMPGVSQESTASHSSPGSTDTTLSPGSTTASSLGP 3330

Query: 1350 KAVEFSSGAKSPSKSGAQTPKSPPEHYVQETPLMFSRCTSVSSLDSFESRSIASSVQSEP 1409
            ++  F SG  S                  ET L+    T+   L++  S  + SS     
Sbjct: 3331 ESTTFHSGPGS-----------------TETTLLPDNTTASGLLEA--STPVHSS----- 3366

Query: 1410 CSGMVSGIISPSDLPDSPG-----QTMPPSRSKTPPPPPQTA 1446
             +G     +SP+      G     Q+ P S+  TP PP  T+
Sbjct: 3367 -TGSPHTTLSPAGSTTRQGESTTFQSWPNSKDTTPAPPTTTS 3407



 Score = 33.9 bits (76), Expect = 2.4
 Identities = 81/382 (21%), Positives = 135/382 (35%), Gaps = 56/382 (14%)

Query: 1177 IDYSLKYATDIPSSQKQSFSFSKSSS--GQSSKTEHMSSSSENTSTPSSNAKRQNQLHPS 1234
            ++ S  Y +   S+Q   F  S ++S  G+ S T H S++   +S PS+ +    +  P+
Sbjct: 826  VEESTTYHSSPGSTQTMHFPESDTTSGRGEESTTSHSSTTHTISSAPSTTSALVEE--PT 883

Query: 1235 SAQSRSGQ------PQKAATCKVSSINQETIQTYCVEDT------PICFSRCSSLSSLSS 1282
            S  S  G       P  + T   S  ++E+  ++  +D       P   +    L   ++
Sbjct: 884  SYHSSPGSTATTHFPDSSTT---SGRSEESTASHSSQDATGTIVLPARSTTSVLLGESTT 940

Query: 1283 AEDEIGCNQTTQEADSANTLQIAEIKEKIGTRSAEDPVSEVPA------VSQHPRTKSSR 1336
            +    G  +TT    S  T  ++E      +       +  PA      VS+   T  SR
Sbjct: 941  SPISSGSMETTALPGSTTTPGLSERSTTFHSSPRSPATTLSPASTTSSGVSEESTTSRSR 1000

Query: 1337 --------LQGSSLSSESARHKAVEFSS-GAKSPSKSGAQTPKSPPEHY---------VQ 1378
                       S+ +   +RH     SS G+   +   A T  S P              
Sbjct: 1001 PGSTHTTAFPDSTTTPGLSRHSTTSHSSPGSTDTTLLPASTTTSGPSQESTTSHSSSGST 1060

Query: 1379 ETPLMFSRCTSVS---SLDSFESRSIASSVQSEPCSGMVSGIISPS----DLPDSPGQTM 1431
            +T L     T++S      +F S   ++     P S   SGI+  S        SP  T+
Sbjct: 1061 DTALSPGSTTALSFGQESTTFHSNPGSTHTTLFPDSTTSSGIVEASTRVHSSTGSPRTTL 1120

Query: 1432 PPSRSKTPP-PPPQTAQTKREVPKNKAPTAEKRESGPKQAAVNAAVQRVQVLPDADTLLH 1490
             P+ S +P      TA        +  P+     + P + +           P +    H
Sbjct: 1121 SPASSTSPGLQGESTAFQTHPASTHTTPSPPSTATAPVEESTT-----YHRSPGSTPTTH 1175

Query: 1491 FATESTPDGFSCSSSLSALSLD 1512
            F   ST  G S  S++   S D
Sbjct: 1176 FPASSTTSGHSEKSTIFHSSPD 1197



 Score = 33.5 bits (75), Expect = 3.1
 Identities = 79/347 (22%), Positives = 126/347 (36%), Gaps = 56/347 (16%)

Query: 1189 SSQKQSFSFSKSSSGQSSKTEHMSSSSENTSTPSSNAK--------RQNQLHPSSAQSRS 1240
            S+    FS S ++ G+S ++  + SS   T+T  S A+             H S   +++
Sbjct: 1865 STPTTHFSASSTTLGRSEESTTVHSSPVATATTPSPARSTTSGLVEESTAYHSSPGSTQT 1924

Query: 1241 GQPQKAATCKVSSINQETIQ---TYCVEDTPICFSRCSSLSSLSSAEDEIGCNQTTQEAD 1297
                +++T    S    T     T+ +   P   S  + +   +S     G   TT   D
Sbjct: 1925 MHFPESSTASGRSEESRTSHSSTTHTISSPPSTTS--ALVEEPTSYHSSPGSTATTHFPD 1982

Query: 1298 SANTLQIAEIKEKIGTRSAEDPVSEV--PAVSQHPRTKSSRLQGSSLSSESARHKAVEFS 1355
            S+ T   +E  E   + S++D    +  PA     R+ +S L G S +            
Sbjct: 1983 SSTTSGRSE--ESTASHSSQDATGTIVLPA-----RSTTSVLLGESTT------------ 2023

Query: 1356 SGAKSPSKSGAQTPKSPPEHYVQETPLMFSRCTSVSSLDSFESRSIASSVQSEPCSGMVS 1415
                SP  SG+    + P      TP +  + T      +F S   + +    P S   S
Sbjct: 2024 ----SPISSGSMETTALPGS--TTTPGLSEKST------TFHSSPRSPATTLSPASTTSS 2071

Query: 1416 GIISPSDLPDS-PGQTMPPS--RSKTPPPPPQTAQTKREVPKNKAPT---AEKRESGPKQ 1469
            G+   S    S PG T   +   S T P   + + T    P +   T   A    SGP Q
Sbjct: 2072 GVSEESTTSHSRPGSTHTTAFPDSTTTPGLSRHSTTSHSSPGSTDTTLLPASTTTSGPSQ 2131

Query: 1470 AAVNA----AVQRVQVLPDADTLLHFATESTPDGFSCSSSLSALSLD 1512
             +  +          + P + T L F  EST    S  S+ + L  D
Sbjct: 2132 ESTTSHSSPGSTDTALSPGSTTALSFGQESTTFHSSPGSTHTTLFPD 2178



 Score = 33.5 bits (75), Expect = 3.1
 Identities = 64/340 (18%), Positives = 122/340 (35%), Gaps = 23/340 (6%)

Query: 1177 IDYSLKYATDIPSSQKQSFSFSKSSSGQSSKTEHMSSSSENTSTPSSNAKRQNQL---HP 1233
            ++    Y +   S+    F  S ++SG+S ++    SS + T T    A+    +     
Sbjct: 3519 VEEPTSYHSSPGSTATTHFPDSSTTSGRSEESTASHSSQDATGTIVLPARSTTSVLLGES 3578

Query: 1234 SSAQSRSGQPQKAA---TCKVSSINQETIQTYCVEDTPICFSRCSSLSSLSSAEDEI--- 1287
            +++   SG  +  A   +     +++++   +    +P      +S +S   +E+     
Sbjct: 3579 TTSPISSGSMETTALPGSTTTPGLSEKSTTFHSSPRSPATTLSPASTTSSGVSEESTTSH 3638

Query: 1288 ---GCNQTTQEADSANTLQIAEIKEKIGTRSAEDPVSEVPAVSQHPRTKSSRLQGSSLSS 1344
               G   TT   DS  T  ++    +  T S   P S    +     T S   Q S+ S 
Sbjct: 3639 SRPGSTHTTAFPDSTTTPGLS----RHSTTSHSSPGSTDTTLLPASTTTSGSSQESTTSH 3694

Query: 1345 ESARHKAVEFSSGAKSPSKSGAQTPKSPPEHYVQETPLMFSRCTSVSSLDSFESRSIASS 1404
             S+       S G+ +    G ++           T L     TS   +++  S  + SS
Sbjct: 3695 SSSGSTDTALSPGSTTALSFGQESTTFHSSPGSTHTTLFPDSTTSSGIVEA--STRVHSS 3752

Query: 1405 VQSEPCSGMVSGIISPSDLPDSPGQTMPPSRSKTPPPPPQ--TAQTKREVPKNKAPTAEK 1462
              S   +   +   SP    +S      P+ + T P PP   TA  +     +++P +  
Sbjct: 3753 TGSPRTTLSPASSTSPGLQGESTAFQTHPASTHTTPSPPSTATAPVEESTTYHRSPGSTP 3812

Query: 1463 RESGPKQAAVNAAVQRVQVL---PDADTLLHFATESTPDG 1499
                P  +  +   ++  +    PDA      +  ST  G
Sbjct: 3813 TTHFPASSTTSGHSEKSTIFHSSPDASGTTPSSAHSTTSG 3852



 Score = 33.5 bits (75), Expect = 3.1
 Identities = 60/276 (21%), Positives = 105/276 (38%), Gaps = 36/276 (13%)

Query: 1177 IDYSLKYATDIPSSQKQSFSFSKSSSGQS--SKTEHMSSSSENTSTPSSNAKRQNQLHPS 1234
            ++ S  Y +   S+Q   F  S ++SG+S  S+T H S++   +S PS+ +    +  P+
Sbjct: 4742 VEESTAYHSSPGSTQTMHFPESSTASGRSEESRTSHSSTTHTISSPPSTTSALVEE--PT 4799

Query: 1235 SAQSRSGQ------PQKAAT---CKVSSINQETIQTYCVEDTPICFSRCSSLS------- 1278
            S  S  G       P+ + T    + S+ +  +  T  +   P  F+    ++       
Sbjct: 4800 SYHSSPGSIATTHFPESSTTSGRSEESTASHSSPDTNGITPLPAHFTTSGRIAESTTFYI 4859

Query: 1279 SLSSAEDEIGCNQTTQEADSANTLQIAEIKEKIGTRSAEDPVSEVPAVSQHPRTKSSRLQ 1338
            S  S E  +    TT    + +T+  +       +RS +  +S     S     + + L 
Sbjct: 4860 SPGSMETTLASTATTPGLSAKSTILYS------SSRSPDQTLSPASMTSSSISGEPTSLY 4913

Query: 1339 GSSLSSESARHKAVEFSSGAKSPSKSGAQTPKSPPEHYVQETPLMFSRCTSVSSLDSF-- 1396
              + S+ +    A   +SG    S +    P S       ET L     T+ S    F  
Sbjct: 4914 SQAESTHTTAFPASTTTSGLSQESTTFHSKPGS------TETTLSPGSITTSSFAQEFTT 4967

Query: 1397 -ESRSIASSVQSEPCSGMVSGIISPS-DLPDSPGQT 1430
              S+  ++     P S  V G+   S     SPG T
Sbjct: 4968 PHSQPGSALSTVSPASTTVPGLSEESTTFYSSPGST 5003



 Score = 33.1 bits (74), Expect = 4.0
 Identities = 68/340 (20%), Positives = 115/340 (33%), Gaps = 23/340 (6%)

Query: 1177 IDYSLKYATDIPSSQKQSFSFSKSSSGQSSKTEHMSSSSENTSTPSSNAKR-------QN 1229
            ++    Y +   S+    F  S ++SG+S ++    SS + T T    A+        ++
Sbjct: 879  VEEPTSYHSSPGSTATTHFPDSSTTSGRSEESTASHSSQDATGTIVLPARSTTSVLLGES 938

Query: 1230 QLHPSSAQSRSGQPQKAATCKVSSINQETIQTYCVEDTPICFSRCSSLSSLSSAEDEI-- 1287
               P S+ S        +T       + T             S  S+ SS  S E     
Sbjct: 939  TTSPISSGSMETTALPGSTTTPGLSERSTTFHSSPRSPATTLSPASTTSSGVSEESTTSR 998

Query: 1288 ---GCNQTTQEADSANTLQIAEIKEKIGTRSAEDPVSEVPAVSQHPRTKSSRLQGSSLSS 1344
               G   TT   DS  T  ++    +  T S   P S    +     T S   Q S+ S 
Sbjct: 999  SRPGSTHTTAFPDSTTTPGLS----RHSTTSHSSPGSTDTTLLPASTTTSGPSQESTTSH 1054

Query: 1345 ESARHKAVEFSSGAKSPSKSGAQTPKSPPEHYVQETPLMFSRCTSVSSLDSFESRSIASS 1404
             S+       S G+ +    G ++           T L     TS   +++  S  + SS
Sbjct: 1055 SSSGSTDTALSPGSTTALSFGQESTTFHSNPGSTHTTLFPDSTTSSGIVEA--STRVHSS 1112

Query: 1405 VQSEPCSGMVSGIISPSDLPDSPGQTMPPSRSKTPPPPPQ--TAQTKREVPKNKAPTAEK 1462
              S   +   +   SP    +S      P+ + T P PP   TA  +     +++P +  
Sbjct: 1113 TGSPRTTLSPASSTSPGLQGESTAFQTHPASTHTTPSPPSTATAPVEESTTYHRSPGSTP 1172

Query: 1463 RESGPKQAAVNAAVQRVQVL---PDADTLLHFATESTPDG 1499
                P  +  +   ++  +    PDA      +  ST  G
Sbjct: 1173 TTHFPASSTTSGHSEKSTIFHSSPDASGTTPSSAHSTTSG 1212



 Score = 32.7 bits (73), Expect = 5.2
 Identities = 60/305 (19%), Positives = 114/305 (37%), Gaps = 30/305 (9%)

Query: 1216 ENTSTPSSNAKRQNQLHPSSAQSRSGQPQKAATCKVSSINQETIQTYCVEDTPICFSRCS 1275
            E+T+ PSS+     +L P+ + + SG   ++   ++S  + ET        TP    + +
Sbjct: 4023 ESTTFPSSSGSTGTKLSPARSTT-SGLVGESTPSRLSPSSTETTTLPGSPTTPSLSEKST 4081

Query: 1276 SLSSLSSAEDEIGCNQTTQEADSANTLQIAEIKEKIGTRSAEDPVSEVPAVSQHPRTKSS 1335
            +  +   + D      TT  +  +     +  +      +A    +    +SQ P T  S
Sbjct: 4082 TFYTSPRSPDATLSPATTTSSGVSEESSTSHSQPGSTHTTAFPDSTTTSGLSQEPTTSHS 4141

Query: 1336 RLQGSSLSSESARHKAVEFSSGAKSPSKSGAQTPKSPPEHYVQETPLMFSRCTSVSSLDS 1395
              QGS+ ++          S G+ + S  G Q+          ET L+          D+
Sbjct: 4142 S-QGSTEAT---------LSPGSTTASSLGQQSTTFHSSPGDTETTLLPD--------DT 4183

Query: 1396 FESRSIASSVQSEPCSGMVSGIISPSDLPDSPGQTMP------PSRSKTPPPPPQTAQTK 1449
              S  + +S  +   +G +   ++P+    +  Q         PS S T P PP T    
Sbjct: 4184 ITSGLVEASTPTHSSTGSLHTTLTPASSTSTGLQEESTTFQSWPSSSDTTPSPPSTT--- 4240

Query: 1450 REVPKNKAPTAEKRESGPKQAAVNAAVQRVQVLPDADTLLHFATESTPDGFSCSSSLSAL 1509
              VP   + T   R S       +A+   +    +  T +H +  +T      + S +++
Sbjct: 4241 -AVPVEVSTTYHSRPSSTPTTHFSASSTTLG-RSEESTTVHSSPGATGTALFPTRSATSV 4298

Query: 1510 SLDEP 1514
             + EP
Sbjct: 4299 LVGEP 4303



 Score = 32.3 bits (72), Expect = 6.9
 Identities = 58/282 (20%), Positives = 107/282 (37%), Gaps = 45/282 (15%)

Query: 1176 PIDYSLKYATDIPSSQKQSFSFSKSSSGQSSKTEHMSSSSENTST---PSSNAKRQNQLH 1232
            P++ S  Y +   S+    FS S ++ G+S ++  + SS   T T   P+ +A       
Sbjct: 1603 PVEVSTTYHSRPSSTPTTHFSASSTTLGRSEESTTVHSSPGATGTALFPTRSATSVLVGE 1662

Query: 1233 PSSAQSRSGQPQKAA---TCKVSSINQETIQTYCVEDTPICFSRCSSLSSLSSAEDEIGC 1289
            P+++   SG  +  A   +   + +++++   Y    +P      ++LS  S+    +  
Sbjct: 1663 PTTSPISSGSTETTALPGSTTTAGLSEKSTTFYSSPRSP-----DTTLSPASTTSSGVSE 1717

Query: 1290 NQTTQEADSANTLQIAEIKEKIGTRSAEDPVSEVPAVSQHPRTKSSRLQGSSLSSESARH 1349
              TT  +   +T             +A    + +P VSQ           S+ S  S   
Sbjct: 1718 ESTTSHSRPGST-----------HTTAFPGSTTMPGVSQE----------STASHSSPGS 1756

Query: 1350 KAVEFSSGAKSPSKSGAQTPKSPPEHYVQETPLMFSRCTSVSSLDSFESRSIASSVQSEP 1409
                 S G+ + S  G ++          ET L+    T+   L++  S  + SS     
Sbjct: 1757 TDTTLSPGSTTASSLGPESTTFHSSPGSTETTLLPDNTTASGLLEA--STPVHSS----- 1809

Query: 1410 CSGMVSGIISPSDLPDSPG-----QTMPPSRSKTPPPPPQTA 1446
             +G     +SP+      G     Q+ P S+   P PP  T+
Sbjct: 1810 -TGSPHTTLSPAGSTTRQGESTTFQSWPSSKDTMPAPPTTTS 1850



 Score = 32.3 bits (72), Expect = 6.9
 Identities = 58/282 (20%), Positives = 107/282 (37%), Gaps = 45/282 (15%)

Query: 1176 PIDYSLKYATDIPSSQKQSFSFSKSSSGQSSKTEHMSSSSENTST---PSSNAKRQNQLH 1232
            P++ S  Y +   S+    FS S ++ G+S ++  + SS   T T   P+ +A       
Sbjct: 4243 PVEVSTTYHSRPSSTPTTHFSASSTTLGRSEESTTVHSSPGATGTALFPTRSATSVLVGE 4302

Query: 1233 PSSAQSRSGQPQKAA---TCKVSSINQETIQTYCVEDTPICFSRCSSLSSLSSAEDEIGC 1289
            P+++   SG  +  A   +   + +++++   Y    +P      ++LS  S+    +  
Sbjct: 4303 PTTSPISSGSTETTALPGSTTTAGLSEKSTTFYSSPRSP-----DTTLSPASTTSSGVSE 4357

Query: 1290 NQTTQEADSANTLQIAEIKEKIGTRSAEDPVSEVPAVSQHPRTKSSRLQGSSLSSESARH 1349
              TT  +   +              +A    + +P VSQ           S+ S  S   
Sbjct: 4358 ESTTSHSRPGSM-----------HTTAFPSSTTMPGVSQE----------STASHSSPGS 4396

Query: 1350 KAVEFSSGAKSPSKSGAQTPKSPPEHYVQETPLMFSRCTSVSSLDSFESRSIASSVQSEP 1409
                 S G+ + S  G ++          ET L+    T+   L++  S  + SS     
Sbjct: 4397 TDTTLSPGSTTASSLGPESTTFHSSPGSTETTLLPDNTTASGLLEA--STPVHSS----- 4449

Query: 1410 CSGMVSGIISPSDLPDSPG-----QTMPPSRSKTPPPPPQTA 1446
             +G     +SP+      G     Q+ P S+  TP PP  T+
Sbjct: 4450 -TGSPHTTLSPAGSTTRQGESTTFQSWPNSKDTTPAPPTTTS 4490


>gi|239508976 PREDICTED: mucin 12, cell surface associated [Homo
            sapiens]
          Length = 2036

 Score = 65.9 bits (159), Expect = 6e-10
 Identities = 161/764 (21%), Positives = 274/764 (35%), Gaps = 88/764 (11%)

Query: 2125 SRQASSDSDSILSLKSGISLGSPFHLTPDQEEKPFTSNKGPRILKPGEKSTLETKKIE-- 2182
            S+++++   S  S  + +S GS   L+  QE   F SN G         ST  +  +E  
Sbjct: 534  SQESTTSHSSSGSTDTALSPGSTTALSFGQESTTFHSNPGSTHTTLFPDSTTSSGIVEAS 593

Query: 2183 ------------------SESKGIKGGKKVYKSLITGKVRSNSEISGQMKQPLQANMPSI 2224
                              S S G++G    +++       + S  S       ++     
Sbjct: 594  TRVHSSTGSPRTTLSPASSTSPGLQGESTAFQTHPASTHTTPSPPSTATAPVEESTTYHR 653

Query: 2225 SRGRT-MIHIPGVRNSSSSTSPVSKKGPPLKTPASKSPSEGQTATTSPRGAKPSVKSELS 2283
            S G T   H P    +SS+TS  S+K     +    S +   +A ++  G   S  S +S
Sbjct: 654  SPGSTPTTHFP----ASSTTSGHSEKSTIFHSSPDASGTTPSSAHSTTSGRGESTTSRIS 709

Query: 2284 PVARQTSQIGGSSKAPSRSGSRDSTPSRPAQ-----QPLSRPIQSPGRNSIS----PGRN 2334
            P + + + + GS+  P  S +  +  S P        P S      G  S +    PG  
Sbjct: 710  PGSTEITTLPGSTTTPGLSEASTTFYSSPRSPTTTLSPASMTSLGVGEESTTSRSQPGST 769

Query: 2335 GISPPNKLSQLPRTSSPSTASTKSS-GSGKMSYTSPGRQMSQQNLTKQTGLSKNAS---S 2390
              +     +  P  S  ST    SS GS + +        S       T  S+ AS   +
Sbjct: 770  HSTVSPASTTTPGLSEESTTVYSSSRGSTETTVFPHSTTTSVHGEEPTTFHSRPASTHTT 829

Query: 2391 IPRSESASKGLNQMNN---GNGANKKVELSRMSSTKSSGSESDRSERPVLVRQSTFIKEA 2447
            +   +S + GL + +    G+ A+ +  L    +T   G ES           ST  K +
Sbjct: 830  LFTEDSTTSGLTEESTAFPGSPASTQTGLPATLTTADLGEESTTFPSS---SGSTGTKLS 886

Query: 2448 PSPTLRRKLEESASFESLSPSSR-----PASPT----RSQAQTPVLSPSLPDMSLSTHSS 2498
            P+ +    L   ++   LSPSS      P SPT      ++ T   SP  PD +LS  ++
Sbjct: 887  PARSTTSGLVGESTPSRLSPSSTETTTLPGSPTTPSLSEKSTTFYTSPRSPDATLSPATT 946

Query: 2499 VQAGGWRKLPPNLSPTIEYNDGRPAKRHDIARSHSESPSRLPINRSGTWKREHSKHSSSL 2558
              +G        +S     +  +P   H  A   S + S L    + +   + S  ++  
Sbjct: 947  TSSG--------VSEESSTSHSQPGSTHTTAFPDSTTTSDLSQEPTTSHSSQGSTEATLS 998

Query: 2559 PRVSTWRRTGSSSSILSASSESSEKAKSEDEKHVNSISGTKQSKENQVSAKGTWRKIKEN 2618
            P  +T    G  S+   +S   +E     D+      SG  ++     S+ G+       
Sbjct: 999  PGSTTASSLGQQSTTFHSSPGDTETTLLPDD---TITSGLVEASTPTHSSTGSLH----- 1050

Query: 2619 EFSPTNSTSQTVSSGATNGAESKTLIYQMAPAVSKTEDVWVRIEDCPINNPRSGRSPTGN 2678
                   T+ T +S  + G + ++  +Q  P+ S T          P+    +  S   +
Sbjct: 1051 -------TTLTPASSTSAGLQEESTTFQSWPSSSDTTPSPPGTTAAPVEVSTTYHSRPSS 1103

Query: 2679 TPPVIDSVSEKANPNIKDSKD-NQAKQNVGNGSVPMRTVGLENRLNSFIQVDAPDQKGTE 2737
            TP    S S       ++S   + +    G    P R+        + + V  P      
Sbjct: 1104 TPTTHFSASSTTLGRSEESTTVHSSPGATGTALFPTRSA-------TSVLVGEPTTSPIS 1156

Query: 2738 IKPGQNNPVPVSETNESSIVERTPFSSSSSSKHS--SPSGTVAARVTPFNYNPSPRKSSA 2795
                +   +P S T      + T F SS  S  +  SP+ T ++ V+  +     R  S 
Sbjct: 1157 SGSTETTALPGSTTTAGLSEKSTTFYSSPRSPDTTLSPASTTSSGVSEESTTSHSRPGST 1216

Query: 2796 DSTSARPSQIPTPVNNNTKKRDSKTDSTESSGTQSPKRHSGSYL 2839
             +T+   S     V+  +    S   ST++  T SP   + S L
Sbjct: 1217 HTTAFPGSTTMPGVSQESTASHSSPGSTDT--TLSPGSTTASSL 1258



 Score = 57.8 bits (138), Expect = 2e-07
 Identities = 132/625 (21%), Positives = 232/625 (37%), Gaps = 71/625 (11%)

Query: 2241 SSTSPVSKKGPPLKTPASKSPSEGQTATTSPRGAKPSVKSELSPVARQTSQIGGSSKAPS 2300
            S+T P S      K   ++S + G    ++P        S LSP + +T+ + GS   PS
Sbjct: 871  STTFPSSSGSTGTKLSPARSTTSGLVGESTP--------SRLSPSSTETTTLPGSPTTPS 922

Query: 2301 RSG----------SRDSTPSRPAQQPLSRPIQSPGRNSISPGRNGISP------PNKLSQ 2344
             S           S D+T S PA    S   +    +   PG    +        + LSQ
Sbjct: 923  LSEKSTTFYTSPRSPDATLS-PATTTSSGVSEESSTSHSQPGSTHTTAFPDSTTTSDLSQ 981

Query: 2345 LPRTSSPSTASTKSSGSGKMSYTSPGRQMSQQNLTKQTGLSKNASSIPRSESASKGLNQM 2404
             P TS  S  ST+++ S   +  S    + QQ+ T  +      +++   ++ + GL + 
Sbjct: 982  EPTTSHSSQGSTEATLSPGSTTAS---SLGQQSTTFHSSPGDTETTLLPDDTITSGLVEA 1038

Query: 2405 NNGNGANKKVELSRMSSTKSSGSESDRSERPVLVRQSTFIKEAPSP--TLRRKLEESASF 2462
            +    ++    L    +  SS S   + E        +     PSP  T    +E S ++
Sbjct: 1039 STPTHSSTG-SLHTTLTPASSTSAGLQEESTTFQSWPSSSDTTPSPPGTTAAPVEVSTTY 1097

Query: 2463 ESLSPSSRPASPTRSQAQTPVLSPSLPDMSLSTHSSVQAGGWRKLPPNLSPTIEYNDGRP 2522
             S  PSS P   T   A +  L  S  + S + HSS  A G    P   + ++   +   
Sbjct: 1098 HS-RPSSTPT--THFSASSTTLGRS--EESTTVHSSPGATGTALFPTRSATSVLVGEPTT 1152

Query: 2523 AKRHDIARSHSESPSRLPINRSGTWKREHSKHSSSLPRVSTWRRTGSSSSILSASSESSE 2582
            +       S S   + LP + +     E S    S PR      + +S++    S ES+ 
Sbjct: 1153 SP----ISSGSTETTALPGSTTTAGLSEKSTTFYSSPRSPDTTLSPASTTSSGVSEESTT 1208

Query: 2583 KAKSEDEKHVNSISGTKQSKENQVSAKGTWRKIKENEFSPTNSTSQTVSSGATN----GA 2638
                    H  +  G+        +  G  ++   +  SP  ST  T+S G+T     G 
Sbjct: 1209 SHSRPGSTHTTAFPGS-------TTMPGVSQESTASHSSP-GSTDTTLSPGSTTASSLGP 1260

Query: 2639 ESKTLIYQMAPAVSKTEDV-------WVRIEDCPINN----PRSGRSPTGNTPPVIDSVS 2687
            ES T  +  +P  ++T  +        +     P+++    P +  SP G+T    +S +
Sbjct: 1261 ESTT--FHSSPGSTETTLLPDNTTASGLLEASTPVHSSTGSPHTTLSPAGSTTRQGESTT 1318

Query: 2688 EKANPNIKDSKDNQAKQNVGNGSVPMRTVGLENRLNS----FIQVDAPDQKGTEIKPGQN 2743
             ++ P+ KD+    A     +  V + T    +  ++    F        +  E     +
Sbjct: 1319 FQSWPSSKDTMP--APPTTTSAFVELSTTSHGSPSSTPTTHFSASSTTLGRSEESTTVHS 1376

Query: 2744 NPVPVSETNESSIVERTPFSSSSSSKHSSPSGTVAARVTPFNYNPSPRKSSADSTSARPS 2803
            +PV  + T   +    +     S++ HSSP  T        +      + S  S S+   
Sbjct: 1377 SPVATATTPSPARSTTSGLVEESTAYHSSPGSTQTMHFPESSTASGRSEESRTSHSSTTH 1436

Query: 2804 QIPTPVNNNTKKRDSKTDSTESSGT 2828
             I +P +  +   +  T    S G+
Sbjct: 1437 TISSPPSTTSALVEEPTSYHSSPGS 1461



 Score = 52.4 bits (124), Expect = 6e-06
 Identities = 134/632 (21%), Positives = 224/632 (35%), Gaps = 93/632 (14%)

Query: 2254 KTPASKSPSEGQTATTSPRGAKPSV------KSELSPVARQTSQIGGSSKAP---SRSGS 2304
            ++ AS S  +    T  P G+ PSV       S +S  + +T+ + GS+  P    +S +
Sbjct: 66   ESKASHSSPDAMATTVLPAGSTPSVLVGDSTPSPISSGSMETTALPGSTTKPGLSEKSTT 125

Query: 2305 RDSTPSRPAQQPLSRPIQSPGRNSIS------PGRNGISPPNKLSQLPRTSSPSTASTKS 2358
              S+P  P    L   + S G +  S      PG    +     + +P  S  STAS  S
Sbjct: 126  FYSSPRSPDTTHLPASMTSSGVSEESTTSHSRPGSTHTTAFPGSTTMPGLSQESTASHSS 185

Query: 2359 SGSGKMSYTSPGRQMSQQNLTKQTGL-----SKNASSIPRSESASKGLNQMN---NGNGA 2410
             G    +  SPG   +     + T       S   + +P + +AS GL + +   + +  
Sbjct: 186  PGPTDTT-LSPGSTTASSLGPEYTTFHSRPGSTETTLLPDNTTAS-GLLEASMPVHSSTR 243

Query: 2411 NKKVELSRMSSTKSSGSESDRSERPVLVRQSTFIKEAPSPTLRRKLEESASFESLSPSSR 2470
            +    LS   ST   G  +     P     S   + AP PT      E ++    SPSS 
Sbjct: 244  SPHTTLSPAGSTTRQGESTTFHSWP----SSKDTRPAP-PTTTSAFVEPSTTSHGSPSSI 298

Query: 2471 PASPTRSQAQTPVLSPSLPDMSLSTHSSVQAGGWRKLPPNLSPTIEY--NDGRPAKRHDI 2528
            P +   +++ T      L + S + HSS          P  + T+ +  +D    +  + 
Sbjct: 299  PTTHISARSTT----SGLVEESTTYHSS----------PGSTQTMHFPESDTTSGRGEES 344

Query: 2529 ARSHSESP---SRLPINRSGTWKREHSKHSSSLPRVSTWRRTGSSSSILSASSESSEKAK 2585
              SHS +    S  P   S   +   S HSS  P  +       SS+    S ES+    
Sbjct: 345  TTSHSSTTHTISSAPSTTSALVEEPTSYHSS--PGSTATTHFPDSSTTSGRSEESTASHS 402

Query: 2586 SEDEKHVNSISGTKQSKENQVSAKGTWRKIKENEFSPTNSTSQTVSSG-----ATNGAES 2640
            S+D     +I    +S  + +  + T   I       T     T + G      T  +  
Sbjct: 403  SQDA--TGTIVLPARSTTSVLLGESTTSPISSGSMETTALPGSTTTPGLSERSTTFHSSP 460

Query: 2641 KTLIYQMAPAVSKTEDVWVRIEDCPINNPRSGRS-----PTGNTPPVID--SVSEKANPN 2693
            ++    ++PA + +  V    E+   +  R G +     P   T P +   S +  ++P 
Sbjct: 461  RSPATTLSPASTTSSGV---SEESTTSRSRPGSTHTTAFPDSTTTPGLSRHSTTSHSSPG 517

Query: 2694 IKDSKDNQAKQNVGNGSVPMRTVGLENRLNSFIQVDAPDQKGTEIKPGQNNPVPVSETNE 2753
              D+             +P  T        S     +     T + PG    +   +   
Sbjct: 518  STDTT-----------LLPASTTTSGPSQESTTSHSSSGSTDTALSPGSTTALSFGQ--- 563

Query: 2754 SSIVERTPFSSSSSSKH-------SSPSGTVAARVTPFNYNPSPRKSSADSTSARPSQIP 2806
                E T F S+  S H       ++ SG V A     +   SPR + + ++S  P    
Sbjct: 564  ----ESTTFHSNPGSTHTTLFPDSTTSSGIVEASTRVHSSTGSPRTTLSPASSTSPGLQG 619

Query: 2807 TPVNNNTKKRDSKTDSTESSGTQSPKRHSGSY 2838
                  T    + T  +  S   +P   S +Y
Sbjct: 620  ESTAFQTHPASTHTTPSPPSTATAPVEESTTY 651



 Score = 48.5 bits (114), Expect = 9e-05
 Identities = 132/631 (20%), Positives = 221/631 (35%), Gaps = 81/631 (12%)

Query: 2223 SISRGRTMIHIPGVRNSSS-STSPVSKKGPPLKTPASKSPSEGQTATTSPRGAKPSVKSE 2281
            S  R     H+P    SS  S    +    P  T  +  P     +TT P  ++ S  S 
Sbjct: 128  SSPRSPDTTHLPASMTSSGVSEESTTSHSRPGSTHTTAFPG----STTMPGLSQESTASH 183

Query: 2282 LSPVARQTSQIGGSSKAPSRSGSRDSTPSRPAQQPLSRPIQSPGRNSISPGRNGISPPNK 2341
             SP    T+   GS+ A S      +  SRP     +     P   + S       P + 
Sbjct: 184  SSPGPTDTTLSPGSTTASSLGPEYTTFHSRPGS---TETTLLPDNTTASGLLEASMPVHS 240

Query: 2342 LSQLPRTSSPSTASTKSSGSGKMSYTSPGRQ--------MSQQNLTKQTGLSKNASSIP- 2392
             ++ P T+     ST   G     ++ P  +         +   +   T    + SSIP 
Sbjct: 241  STRSPHTTLSPAGSTTRQGESTTFHSWPSSKDTRPAPPTTTSAFVEPSTTSHGSPSSIPT 300

Query: 2393 ---RSESASKGL----NQMNNGNGANKKVELSRMSSTKSSGSESDRSERPVLVRQSTFIK 2445
                + S + GL       ++  G+ + +      +T   G ES  S        +  I 
Sbjct: 301  THISARSTTSGLVEESTTYHSSPGSTQTMHFPESDTTSGRGEESTTSHSST----THTIS 356

Query: 2446 EAPSPTLRRKLEESASFESLSPSSRPASPTRSQAQTPVLSPSLPDMSLSTHSSVQAGGWR 2505
             APS T    +EE  S+ S SP S   +     + T   S    + S ++HSS  A G  
Sbjct: 357  SAPS-TTSALVEEPTSYHS-SPGSTATTHFPDSSTTSGRS----EESTASHSSQDATGTI 410

Query: 2506 KLPPNLSPTIEYNDGRPAKRHDIARSHSESPSRLPINRSGTWKREHSKHSSSLPRVSTWR 2565
             LP   + ++   +   +       S S   + LP + +     E S    S PR     
Sbjct: 411  VLPARSTTSVLLGESTTSP----ISSGSMETTALPGSTTTPGLSERSTTFHSSPR----- 461

Query: 2566 RTGSSSSILSASSESSEKAKSEDEKHVNSISGTKQSKENQVSAKGTWRKIKENEFSPTNS 2625
               S ++ LS +S +S              SG  +      S  G+       + + T  
Sbjct: 462  ---SPATTLSPASTTS--------------SGVSEESTTSRSRPGSTHTTAFPDSTTTPG 504

Query: 2626 TSQ-TVSSGATNGAESKTLIYQMAPAVSKTEDVWVRIEDCPINNPRSGRSPTGNTPPVID 2684
             S+ + +S ++ G+   TL+    PA + T          P     +  S +G+T   + 
Sbjct: 505  LSRHSTTSHSSPGSTDTTLL----PASTTTSG--------PSQESTTSHSSSGSTDTALS 552

Query: 2685 SVSEKANPNIKDSKDNQAKQNVGNGSVPMRTVGLENRLNSFIQVDAPDQKGTEIKPGQNN 2744
              S  A      S   ++     N      T+  ++  +S I V+A  +  +     +  
Sbjct: 553  PGSTTAL-----SFGQESTTFHSNPGSTHTTLFPDSTTSSGI-VEASTRVHSSTGSPRTT 606

Query: 2745 PVPVSETNESSIVERTPFSSSSSSKHSSPSGTVAARVTPFNYNPSPRKSSADSTSARPSQ 2804
              P S T+     E T F +  +S H++PS    A           R   +  T+  P+ 
Sbjct: 607  LSPASSTSPGLQGESTAFQTHPASTHTTPSPPSTATAPVEESTTYHRSPGSTPTTHFPAS 666

Query: 2805 IPTPVNNNTKKRDSKTDSTESSGTQSPKRHS 2835
              T  + +++K      S ++SGT     HS
Sbjct: 667  STT--SGHSEKSTIFHSSPDASGTTPSSAHS 695



 Score = 47.4 bits (111), Expect = 2e-04
 Identities = 156/729 (21%), Positives = 256/729 (35%), Gaps = 128/729 (17%)

Query: 2197 SLITGKVRSNSEISGQMKQ---PLQANMPSISRGRTMIHIPGVRNSSSSTSPVSKKGPPL 2253
            S++ G+  ++   SG M+    P     P +S   T  H       SS  SP +      
Sbjct: 419  SVLLGESTTSPISSGSMETTALPGSTTTPGLSERSTTFH-------SSPRSPATTL---- 467

Query: 2254 KTPASKSPSEGQTATTSPRGAKPSVKSELSPVARQTSQIGGSSKAPSRSGSRDSTPSRPA 2313
             +PAS + S     +T+ R    S  +   P +  T  +   S     S     T   PA
Sbjct: 468  -SPASTTSSGVSEESTTSRSRPGSTHTTAFPDSTTTPGLSRHSTTSHSSPGSTDTTLLPA 526

Query: 2314 QQPLSRPIQ-------SPGR--NSISPG---------------RNGISPPNKLSQLPRTS 2349
                S P Q       S G    ++SPG                N  S    L     TS
Sbjct: 527  STTTSGPSQESTTSHSSSGSTDTALSPGSTTALSFGQESTTFHSNPGSTHTTLFPDSTTS 586

Query: 2350 S----PSTASTKSSGSGK-----MSYTSPGRQ------MSQQNLTKQTGLSKNASSIPRS 2394
            S     ST    S+GS +      S TSPG Q       +    T  T    + ++ P  
Sbjct: 587  SGIVEASTRVHSSTGSPRTTLSPASSTSPGLQGESTAFQTHPASTHTTPSPPSTATAPVE 646

Query: 2395 ESA----------SKGLNQMNNGNGANKKVELSRMSSTKSSGSESDRSERPVLVRQSTFI 2444
            ES           +      +  +G ++K  +   S   S  + S          +ST  
Sbjct: 647  ESTTYHRSPGSTPTTHFPASSTTSGHSEKSTIFHSSPDASGTTPSSAHSTTSGRGESTTS 706

Query: 2445 KEAPSPTLRRKLEESASFESLSPS-----SRPASPTRSQAQTPVLSPSLPDMSL------ 2493
            + +P  T    L  S +   LS +     S P SPT + +   + S  + + S       
Sbjct: 707  RISPGSTEITTLPGSTTTPGLSEASTTFYSSPRSPTTTLSPASMTSLGVGEESTTSRSQP 766

Query: 2494 -STHSSVQAGGWRKLPPNLSPTIEYNDGRPAKR-----HDIARS-HSESPSRL---PINR 2543
             STHS+V          +   T  Y+  R +       H    S H E P+     P + 
Sbjct: 767  GSTHSTVSPASTTTPGLSEESTTVYSSSRGSTETTVFPHSTTTSVHGEEPTTFHSRPAST 826

Query: 2544 SGTWKREHS------KHSSSLPRVSTWRRTGSSSSILSAS-SESSEKAKSEDEKHVNSIS 2596
              T   E S      + S++ P      +TG  +++ +A   E S    S      +  +
Sbjct: 827  HTTLFTEDSTTSGLTEESTAFPGSPASTQTGLPATLTTADLGEESTTFPSS-----SGST 881

Query: 2597 GTKQSKENQVSAKGTWRKIKENEFSPTNSTSQTVSSGATNG--AESKTLIY--------Q 2646
            GTK S     ++ G   +   +  SP+++ + T+    T    +E  T  Y         
Sbjct: 882  GTKLSPARSTTS-GLVGESTPSRLSPSSTETTTLPGSPTTPSLSEKSTTFYTSPRSPDAT 940

Query: 2647 MAPAVSKTEDVWVRIEDCPINNPRSGRSPTGNTPPVIDSVSEKANPNIKDSKDNQAKQNV 2706
            ++PA + +  V    E+   ++ + G + T   P    +      P    S     +  +
Sbjct: 941  LSPATTTSSGV---SEESSTSHSQPGSTHTTAFPDSTTTSDLSQEPTTSHSSQGSTEATL 997

Query: 2707 GNGSVPMRTVGLENRLNSFIQVDAPDQKGTEIKPGQNNPVPVSETNESSIVE-RTPFSSS 2765
              GS    ++G +    S     +P    T + P         +T  S +VE  TP  SS
Sbjct: 998  SPGSTTASSLGQQ----STTFHSSPGDTETTLLP--------DDTITSGLVEASTPTHSS 1045

Query: 2766 SSSKHS--SPSGTVAARVTPFNYNPSPRKSSADSTSARPSQIPTPVNNNT--KKRDSKTD 2821
            + S H+  +P+ + +A +   +       SS+D+T + P     PV  +T    R S T 
Sbjct: 1046 TGSLHTTLTPASSTSAGLQEESTTFQSWPSSSDTTPSPPGTTAAPVEVSTTYHSRPSSTP 1105

Query: 2822 STESSGTQS 2830
            +T  S + +
Sbjct: 1106 TTHFSASST 1114



 Score = 45.4 bits (106), Expect = 8e-04
 Identities = 72/308 (23%), Positives = 118/308 (38%), Gaps = 37/308 (12%)

Query: 2224 ISRGRT-MIHIPGVRNSSSSTSPVSKKGPPL-KTPASKSPSEGQTATTSPRGAKPSVKSE 2281
            IS G T    +PG    S++T+ +S+K      +P S   +    +TTS   ++ S  S 
Sbjct: 1155 ISSGSTETTALPG----STTTAGLSEKSTTFYSSPRSPDTTLSPASTTSSGVSEESTTSH 1210

Query: 2282 LSPVARQTSQIGGSSKAPSRSGSRDSTPSRPAQQPLSRPIQSPGRNSISPGRNGI--SPP 2339
              P +  T+   GS+  P  S    ++ S P     +    S   +S+ P       SP 
Sbjct: 1211 SRPGSTHTTAFPGSTTMPGVSQESTASHSSPGSTDTTLSPGSTTASSLGPESTTFHSSPG 1270

Query: 2340 NKLSQLPRTSSPSTASTKSSGSGKMSYTSPGRQMSQQNLTKQTGLSKNASSIPRSE---- 2395
            +  + L   ++ ++   ++S     S  SP   +S    T + G S    S P S+    
Sbjct: 1271 STETTLLPDNTTASGLLEASTPVHSSTGSPHTTLSPAGSTTRQGESTTFQSWPSSKDTMP 1330

Query: 2396 ------SASKGLNQMNNGNGANKKVELSRMSSTKSSGSESD-----------------RS 2432
                  SA   L+  ++G+ ++        SST    SE                   RS
Sbjct: 1331 APPTTTSAFVELSTTSHGSPSSTPTTHFSASSTTLGRSEESTTVHSSPVATATTPSPARS 1390

Query: 2433 ERPVLVRQSTFIKEAPSPTLRRKLEESASFESLSPSSRP--ASPTRSQAQTPVLSPSLPD 2490
                LV +ST    +P  T      ES++    S  SR   +S T + +  P  + +L +
Sbjct: 1391 TTSGLVEESTAYHSSPGSTQTMHFPESSTASGRSEESRTSHSSTTHTISSPPSTTSALVE 1450

Query: 2491 MSLSTHSS 2498
               S HSS
Sbjct: 1451 EPTSYHSS 1458



 Score = 43.5 bits (101), Expect = 0.003
 Identities = 87/442 (19%), Positives = 165/442 (37%), Gaps = 51/442 (11%)

Query: 2425 SGSESDRSERPVLVRQSTFIKEAPSPTLRRKLEESASFESLSPSSRPASPTRSQAQTPVL 2484
            S + S  SE       ST   ++ +P+    L  ++   SL  +      T  +  + + 
Sbjct: 6    SSTTSGHSEESATFHGSTTHTKSSTPSTTAALAHTSYHSSLGSTET----THFRDSSTIS 61

Query: 2485 SPSLPDMSLSTHSSVQAGGWRKLPPNLSPTIEYNDGRPAKRHDIARSHSESPSRLPINRS 2544
              S  + S ++HSS  A     LP   +P++   D  P+       S S   + LP + +
Sbjct: 62   GRS--EESKASHSSPDAMATTVLPAGSTPSVLVGDSTPSP----ISSGSMETTALPGSTT 115

Query: 2545 GTWKREHSKHSSSLPRVSTWRRTGSSSSILSASSESSEKAKSEDEKHVNSISG--TKQSK 2602
                 E S    S PR        +S +    S ES+         H  +  G  T    
Sbjct: 116  KPGLSEKSTTFYSSPRSPDTTHLPASMTSSGVSEESTTSHSRPGSTHTTAFPGSTTMPGL 175

Query: 2603 ENQVSAKGTWRKIKENEFSPTNSTSQTVSSGATN-----GAESKTLIYQMAPAVSKTEDV 2657
              + +A  +     +   SP ++T+ ++    T      G+   TL+     A    E  
Sbjct: 176  SQESTASHSSPGPTDTTLSPGSTTASSLGPEYTTFHSRPGSTETTLLPDNTTASGLLE-- 233

Query: 2658 WVRIEDCPIN----NPRSGRSPTGNTPPVIDSVSEKANPNIKDSK-----------DNQA 2702
                   P++    +P +  SP G+T    +S +  + P+ KD++           +   
Sbjct: 234  ----ASMPVHSSTRSPHTTLSPAGSTTRQGESTTFHSWPSSKDTRPAPPTTTSAFVEPST 289

Query: 2703 KQNVGNGSVPMRTVGLENRLNSFIQVDAPDQKGTEIKPGQNNPVPVSETNESSIVERTPF 2762
              +    S+P   +   +  +  ++    +       PG    +   E++ +S       
Sbjct: 290  TSHGSPSSIPTTHISARSTTSGLVE----ESTTYHSSPGSTQTMHFPESDTTSGRGEEST 345

Query: 2763 SSSSSSKH---SSPSGTVAARVTPFNYNPSPRKSSADSTSARPSQIPTPVNNNTKKRDSK 2819
            +S SS+ H   S+PS T A    P +Y+ SP    + +T+  P    T  +  +++  + 
Sbjct: 346  TSHSSTTHTISSAPSTTSALVEEPTSYHSSP---GSTATTHFPDSSTT--SGRSEESTAS 400

Query: 2820 TDSTESSGT-QSPKRHSGSYLV 2840
              S +++GT   P R + S L+
Sbjct: 401  HSSQDATGTIVLPARSTTSVLL 422



 Score = 39.7 bits (91), Expect = 0.043
 Identities = 73/360 (20%), Positives = 133/360 (36%), Gaps = 30/360 (8%)

Query: 1176 PIDYSLKYATDIPSSQKQSFSFSKSSSGQSSKTEHMSSSSENTSTPSSNAKRQNQLHPSS 1235
            P++ S  Y     S+    F  S ++SG S K+    SS + + T  S+A         S
Sbjct: 644  PVEESTTYHRSPGSTPTTHFPASSTTSGHSEKSTIFHSSPDASGTTPSSAHSTTSGRGES 703

Query: 1236 AQSRSGQPQKAATCKVSS-----INQETIQTYCVEDTPICFSRCSSLSSLSSAED----- 1285
              SR        T    S     +++ +   Y    +P      +S++SL   E+     
Sbjct: 704  TTSRISPGSTEITTLPGSTTTPGLSEASTTFYSSPRSPTTTLSPASMTSLGVGEESTTSR 763

Query: 1286 -EIGCNQTTQEADSANTLQIAEIKEKIGTRSAEDPVSEVPAVSQHPRTKSSRLQGSSLSS 1344
             + G   +T    S  T  ++E    + + S     + V      P + ++ + G   ++
Sbjct: 764  SQPGSTHSTVSPASTTTPGLSEESTTVYSSSRGSTETTV-----FPHSTTTSVHGEEPTT 818

Query: 1345 ESARHKAVEFSSGAKSPSKSG--AQTPKSPPEHYVQETPLMFSRCTSVSSLDS--FESRS 1400
              +R  +   +   +  + SG   ++   P      +T L  +  T+    +S  F S S
Sbjct: 819  FHSRPASTHTTLFTEDSTTSGLTEESTAFPGSPASTQTGLPATLTTADLGEESTTFPSSS 878

Query: 1401 IASSVQSEPCSGMVSGII---SPSDLPDSPGQTMPPSRSKTPPPPPQTAQTKREVPKNKA 1457
             ++  +  P     SG++   +PS L  S  +T     S T P   + + T    P++  
Sbjct: 879  GSTGTKLSPARSTTSGLVGESTPSRLSPSSTETTTLPGSPTTPSLSEKSTTFYTSPRSPD 938

Query: 1458 PT---AEKRESGPKQAAVNAAVQ----RVQVLPDADTLLHFATESTPDGFSCSSSLSALS 1510
             T   A    SG  + +  +  Q         PD+ T    + E T    S  S+ + LS
Sbjct: 939  ATLSPATTTSSGVSEESSTSHSQPGSTHTTAFPDSTTTSDLSQEPTTSHSSQGSTEATLS 998



 Score = 33.9 bits (76), Expect = 2.4
 Identities = 81/382 (21%), Positives = 135/382 (35%), Gaps = 56/382 (14%)

Query: 1177 IDYSLKYATDIPSSQKQSFSFSKSSS--GQSSKTEHMSSSSENTSTPSSNAKRQNQLHPS 1234
            ++ S  Y +   S+Q   F  S ++S  G+ S T H S++   +S PS+ +    +  P+
Sbjct: 313  VEESTTYHSSPGSTQTMHFPESDTTSGRGEESTTSHSSTTHTISSAPSTTSALVEE--PT 370

Query: 1235 SAQSRSGQ------PQKAATCKVSSINQETIQTYCVEDT------PICFSRCSSLSSLSS 1282
            S  S  G       P  + T   S  ++E+  ++  +D       P   +    L   ++
Sbjct: 371  SYHSSPGSTATTHFPDSSTT---SGRSEESTASHSSQDATGTIVLPARSTTSVLLGESTT 427

Query: 1283 AEDEIGCNQTTQEADSANTLQIAEIKEKIGTRSAEDPVSEVPA------VSQHPRTKSSR 1336
            +    G  +TT    S  T  ++E      +       +  PA      VS+   T  SR
Sbjct: 428  SPISSGSMETTALPGSTTTPGLSERSTTFHSSPRSPATTLSPASTTSSGVSEESTTSRSR 487

Query: 1337 --------LQGSSLSSESARHKAVEFSS-GAKSPSKSGAQTPKSPPEHY---------VQ 1378
                       S+ +   +RH     SS G+   +   A T  S P              
Sbjct: 488  PGSTHTTAFPDSTTTPGLSRHSTTSHSSPGSTDTTLLPASTTTSGPSQESTTSHSSSGST 547

Query: 1379 ETPLMFSRCTSVS---SLDSFESRSIASSVQSEPCSGMVSGIISPS----DLPDSPGQTM 1431
            +T L     T++S      +F S   ++     P S   SGI+  S        SP  T+
Sbjct: 548  DTALSPGSTTALSFGQESTTFHSNPGSTHTTLFPDSTTSSGIVEASTRVHSSTGSPRTTL 607

Query: 1432 PPSRSKTPP-PPPQTAQTKREVPKNKAPTAEKRESGPKQAAVNAAVQRVQVLPDADTLLH 1490
             P+ S +P      TA        +  P+     + P + +           P +    H
Sbjct: 608  SPASSTSPGLQGESTAFQTHPASTHTTPSPPSTATAPVEESTT-----YHRSPGSTPTTH 662

Query: 1491 FATESTPDGFSCSSSLSALSLD 1512
            F   ST  G S  S++   S D
Sbjct: 663  FPASSTTSGHSEKSTIFHSSPD 684



 Score = 33.9 bits (76), Expect = 2.4
 Identities = 123/643 (19%), Positives = 218/643 (33%), Gaps = 45/643 (6%)

Query: 1895 TSHTELTSNQQSANKTQAIAKQPINRGQPKPI-LQKQSTFPQSSKDIPDRGAATDEKLQN 1953
            T+ ++L+    +++ +Q   +  ++ G      L +QST   SS    +     D+ + +
Sbjct: 974  TTTSDLSQEPTTSHSSQGSTEATLSPGSTTASSLGQQSTTFHSSPGDTETTLLPDDTITS 1033

Query: 1954 FAIE-NTPVCFSHNSSLSSLSDIDQENNNKENEPIKETEPPDSQGEPSKPQASGYAPKSF 2012
              +E +TP   S  S  ++L+     +   + E       P S      P  +  AP   
Sbjct: 1034 GLVEASTPTHSSTGSLHTTLTPASSTSAGLQEESTTFQSWPSSSDTTPSPPGTTAAP--- 1090

Query: 2013 HVEDTPVCFSRNSSLSSLSIDSEDDLLQECISSA-------------MPKKKKPSRLKGD 2059
             VE +    SR SS  +    +    L     S               P +   S L G+
Sbjct: 1091 -VEVSTTYHSRPSSTPTTHFSASSTTLGRSEESTTVHSSPGATGTALFPTRSATSVLVGE 1149

Query: 2060 NEKHSPRNMGG-----ILGEDLTLDLKDIQRPDSEHGLSPDSENFDWKAIQEGANSIVSS 2114
                SP + G      + G   T  L +          SPD+          G +   ++
Sbjct: 1150 PTT-SPISSGSTETTALPGSTTTAGLSEKSTTFYSSPRSPDTTLSPASTTSSGVSEESTT 1208

Query: 2115 LHQAAAAACLSRQASSDSDSILSLKSGISLGSPFHLTPDQEEKPFT-SNKGPRIL----K 2169
             H    +   +    S +   +S +S  S  SP            T S+ GP        
Sbjct: 1209 SHSRPGSTHTTAFPGSTTMPGVSQESTASHSSPGSTDTTLSPGSTTASSLGPESTTFHSS 1268

Query: 2170 PGEKSTLETKKIESESKGIKGGKKVYKSLITGKVRSNSEISGQM-KQPLQANMPSISRGR 2228
            PG   T       + S  ++    V+ S  TG   +    +G   +Q       S    +
Sbjct: 1269 PGSTETTLLPDNTTASGLLEASTPVHSS--TGSPHTTLSPAGSTTRQGESTTFQSWPSSK 1326

Query: 2229 TMIHIPGVRNSSSSTSPVSKKGPPLKTPASKSPSEGQTA-----TTSPRGAKPSVKSELS 2283
              +  P    S+      +  G P  TP +   +   T      +T+   +  +  +  S
Sbjct: 1327 DTMPAPPTTTSAFVELSTTSHGSPSSTPTTHFSASSTTLGRSEESTTVHSSPVATATTPS 1386

Query: 2284 PVARQTSQIGGSSKAPSRSGSRDSTPSRPAQQPLSRPIQSPGRNSISPGRNGISPPNKLS 2343
            P    TS +   S A   S     T   P     S   +    +  S      SPP+  S
Sbjct: 1387 PARSTTSGLVEESTAYHSSPGSTQTMHFPESSTASGRSEESRTSHSSTTHTISSPPSTTS 1446

Query: 2344 QLPR--TSSPSTASTKSSGSGKMSYTSPGRQMSQQNLTKQTGLSKNA-SSIPRSESASKG 2400
             L    TS  S+  + ++     S T+ GR  S+++    +    N  + +P   + S  
Sbjct: 1447 ALVEEPTSYHSSPGSIATTHFPESSTTSGR--SEESTASHSSPDTNGITPLPAHFTTSGR 1504

Query: 2401 LNQMNNG--NGANKKVELSRMSSTKSSGSESDRSERPVLVRQSTFIKEAPSPTLRRKLEE 2458
            + +      +  + +  L+  ++T    ++S       LV + T    +PSPT       
Sbjct: 1505 IAESTTFYISPGSMETTLASTATTPGLSAKSTILYTSDLVGEPTTFYISPSPTYTTLFPA 1564

Query: 2459 SASFESLSPSSRPASPTRSQAQTPVLSPSLPDMSLSTHSSVQA 2501
            S+S   L+  S     + S   T V + SL  ++  T   + A
Sbjct: 1565 SSSTSGLTEESTTFHTSPSFTSTIVSTESLETLAPETPEKLNA 1607



 Score = 33.1 bits (74), Expect = 4.0
 Identities = 68/340 (20%), Positives = 115/340 (33%), Gaps = 23/340 (6%)

Query: 1177 IDYSLKYATDIPSSQKQSFSFSKSSSGQSSKTEHMSSSSENTSTPSSNAKR-------QN 1229
            ++    Y +   S+    F  S ++SG+S ++    SS + T T    A+        ++
Sbjct: 366  VEEPTSYHSSPGSTATTHFPDSSTTSGRSEESTASHSSQDATGTIVLPARSTTSVLLGES 425

Query: 1230 QLHPSSAQSRSGQPQKAATCKVSSINQETIQTYCVEDTPICFSRCSSLSSLSSAEDEI-- 1287
               P S+ S        +T       + T             S  S+ SS  S E     
Sbjct: 426  TTSPISSGSMETTALPGSTTTPGLSERSTTFHSSPRSPATTLSPASTTSSGVSEESTTSR 485

Query: 1288 ---GCNQTTQEADSANTLQIAEIKEKIGTRSAEDPVSEVPAVSQHPRTKSSRLQGSSLSS 1344
               G   TT   DS  T  ++    +  T S   P S    +     T S   Q S+ S 
Sbjct: 486  SRPGSTHTTAFPDSTTTPGLS----RHSTTSHSSPGSTDTTLLPASTTTSGPSQESTTSH 541

Query: 1345 ESARHKAVEFSSGAKSPSKSGAQTPKSPPEHYVQETPLMFSRCTSVSSLDSFESRSIASS 1404
             S+       S G+ +    G ++           T L     TS   +++  S  + SS
Sbjct: 542  SSSGSTDTALSPGSTTALSFGQESTTFHSNPGSTHTTLFPDSTTSSGIVEA--STRVHSS 599

Query: 1405 VQSEPCSGMVSGIISPSDLPDSPGQTMPPSRSKTPPPPPQ--TAQTKREVPKNKAPTAEK 1462
              S   +   +   SP    +S      P+ + T P PP   TA  +     +++P +  
Sbjct: 600  TGSPRTTLSPASSTSPGLQGESTAFQTHPASTHTTPSPPSTATAPVEESTTYHRSPGSTP 659

Query: 1463 RESGPKQAAVNAAVQRVQVL---PDADTLLHFATESTPDG 1499
                P  +  +   ++  +    PDA      +  ST  G
Sbjct: 660  TTHFPASSTTSGHSEKSTIFHSSPDASGTTPSSAHSTTSG 699



 Score = 32.3 bits (72), Expect = 6.9
 Identities = 58/282 (20%), Positives = 107/282 (37%), Gaps = 45/282 (15%)

Query: 1176 PIDYSLKYATDIPSSQKQSFSFSKSSSGQSSKTEHMSSSSENTST---PSSNAKRQNQLH 1232
            P++ S  Y +   S+    FS S ++ G+S ++  + SS   T T   P+ +A       
Sbjct: 1090 PVEVSTTYHSRPSSTPTTHFSASSTTLGRSEESTTVHSSPGATGTALFPTRSATSVLVGE 1149

Query: 1233 PSSAQSRSGQPQKAA---TCKVSSINQETIQTYCVEDTPICFSRCSSLSSLSSAEDEIGC 1289
            P+++   SG  +  A   +   + +++++   Y    +P      ++LS  S+    +  
Sbjct: 1150 PTTSPISSGSTETTALPGSTTTAGLSEKSTTFYSSPRSP-----DTTLSPASTTSSGVSE 1204

Query: 1290 NQTTQEADSANTLQIAEIKEKIGTRSAEDPVSEVPAVSQHPRTKSSRLQGSSLSSESARH 1349
              TT  +   +T             +A    + +P VSQ           S+ S  S   
Sbjct: 1205 ESTTSHSRPGST-----------HTTAFPGSTTMPGVSQE----------STASHSSPGS 1243

Query: 1350 KAVEFSSGAKSPSKSGAQTPKSPPEHYVQETPLMFSRCTSVSSLDSFESRSIASSVQSEP 1409
                 S G+ + S  G ++          ET L+    T+   L++  S  + SS     
Sbjct: 1244 TDTTLSPGSTTASSLGPESTTFHSSPGSTETTLLPDNTTASGLLEA--STPVHSS----- 1296

Query: 1410 CSGMVSGIISPSDLPDSPG-----QTMPPSRSKTPPPPPQTA 1446
             +G     +SP+      G     Q+ P S+   P PP  T+
Sbjct: 1297 -TGSPHTTLSPAGSTTRQGESTTFQSWPSSKDTMPAPPTTTS 1337


>gi|151301154 mucin 6, gastric [Homo sapiens]
          Length = 2439

 Score = 65.5 bits (158), Expect = 7e-10
 Identities = 130/636 (20%), Positives = 209/636 (32%), Gaps = 106/636 (16%)

Query: 2252 PLKTPASKSPSEGQTATTSPRGAKPSVKSELSPVARQTSQIGGSSKAPSRSGSRDSTPSR 2311
            P  TP  + P+  Q  TT  R  +    +  S      S  G S  +     S   TP  
Sbjct: 1198 PPTTP--QPPTTPQLPTTGSRPTQVWPMTGTSTTIGLLSSTGPSPSSNHTPASPTQTPLL 1255

Query: 2312 PAQQPLSRPIQSPGRNSISPGRNGISPPNKLSQLPRTSSPSTASTK-----SSGSGKMSY 2366
            PA    S+P  S G     P       P   S LP T++  + +TK     ++     S 
Sbjct: 1256 PATLTSSKPTASSGE---PPRPTTAVTPQATSGLPPTATLRSTATKPTVTQATTRATAST 1312

Query: 2367 TSPGRQMSQQNLTKQTGLSKNASSIPRSESASKGLNQMNNGNGANKKV--ELSRMSSTKS 2424
             SP    + Q+ T+ T      ++   S +  K  NQ   G  A +      +  S+T  
Sbjct: 1313 ASPATTSTAQSTTRTTMTLPTPATSGTSPTLPKSTNQELPGTTATQTTGPRPTPASTTGP 1372

Query: 2425 SGSESDRSERPVLVR--QSTFIKEAPSPTLRRKLEESASFESLSPSSRPASPTRSQAQTP 2482
            +  +  +  RP      Q+    E  +P          +  S  PS+ P + T   A T 
Sbjct: 1373 TTPQPGQPTRPTATETTQTRTTTEYTTPQTPHTTHSPPTAGSPVPSTGPVTATSFHATTT 1432

Query: 2483 VLSPSLPDMSLSTHSSVQAGGWRKLPPNLSPTIEYNDGRPAKRHDIARSHSESPSRLPIN 2542
              +PS P+ +L TH          +PP  +  +      P+    I  +H++        
Sbjct: 1433 YPTPSHPETTLPTH----------VPPFSTSLV-----TPSTHTVITPTHAQ-------- 1469

Query: 2543 RSGTWKREHSKHSSSLPRVSTWRRTGS-----------SSSILSASSESSEKAKSEDEKH 2591
               T    HS  + ++P  +T + TGS           S +  + SS S+ K  +    H
Sbjct: 1470 -MATSASNHSAPTGTIPPPTTLKATGSTHTAPPITPTTSGTSQAHSSFSTNKTPTSLHSH 1528

Query: 2592 VNSI-------SGTKQSKENQVSAKGTWRKIKENE------------FSPTNSTSQTVSS 2632
             +S        + T     N  S +        N              SP   +S   S+
Sbjct: 1529 TSSTHHPEVTPTSTTTITPNPTSTRTRTPVAHTNSATSSRPPPPFTTHSPPTGSSPFSST 1588

Query: 2633 GATNGAESKTLIYQMAPA------------------VSKTEDVWVRIEDCPINNPRSGRS 2674
            G       KT      P+                     T  V          +      
Sbjct: 1589 GPMTATSFKTTTTYPTPSHPQTTLPTHVPPFSTSLVTPSTHTVITPTHAQMATSASIHSM 1648

Query: 2675 PTGNTPP-----VIDSVSEKANPNIKDSKDNQAKQNVGNGSVPMRTVGLENRLNSFIQVD 2729
            PTG  PP        S        +  S  +QA  ++        +  L +  +S    +
Sbjct: 1649 PTGTIPPPTTLKATGSTHTAPTMTLTTSGTSQALSSLNTAKT---STSLHSHTSSTHHAE 1705

Query: 2730 APDQKGTEIKPG--QNNPVPVSETNESSIVERTPFSS----------SSSSKHSSPSGTV 2777
            A     T I P        P++ T   +   R+ FS+          +SS+ H   + T 
Sbjct: 1706 ATSTSTTNITPNPTSTGTPPMTVTTSGTSQSRSSFSTAKTSTSLHSHTSSTHHPEVTSTS 1765

Query: 2778 AARVTPFNYNPSPRKSSADSTSARPSQIPTPVNNNT 2813
               +TP + +   R   A +TSA  S++PTP   ++
Sbjct: 1766 TTSITPNHTSTGTRTPVAHTTSATSSRLPTPFTTHS 1801



 Score = 53.1 bits (126), Expect = 4e-06
 Identities = 135/690 (19%), Positives = 243/690 (35%), Gaps = 133/690 (19%)

Query: 2225 SRGRTMIHIPGVRNSSSSTSPVSKKGPPLKTPASKSPSEGQTATTSPRGAKPSVKSELSP 2284
            S  RT + +P    ++S TSP   K    + P + +     T TT PR    S     +P
Sbjct: 1323 STTRTTMTLP--TPATSGTSPTLPKSTNQELPGTTA-----TQTTGPRPTPASTTGPTTP 1375

Query: 2285 VARQTSQIGGSSKAPSRSGSRDSTPSRP----------AQQPLSRPIQSPGRNSISPGRN 2334
               Q ++   +    +R+ +  +TP  P          +  P + P+ +   ++ +    
Sbjct: 1376 QPGQPTRPTATETTQTRTTTEYTTPQTPHTTHSPPTAGSPVPSTGPVTATSFHATTTYPT 1435

Query: 2335 GISPPNKLSQ----------LPRTSSPSTASTKSSGSGKMSYTSPGRQMSQQNLTKQTGL 2384
               P   L             P T +  T +     +   ++++P   +      K TG 
Sbjct: 1436 PSHPETTLPTHVPPFSTSLVTPSTHTVITPTHAQMATSASNHSAPTGTIPPPTTLKATGS 1495

Query: 2385 SKNA----------SSIPRSESASKGLNQMNNGNGANKKVELSRMSSTK-SSGSESDRSE 2433
            +  A          S    S S +K    +++   +    E++  S+T  +    S R+ 
Sbjct: 1496 THTAPPITPTTSGTSQAHSSFSTNKTPTSLHSHTSSTHHPEVTPTSTTTITPNPTSTRTR 1555

Query: 2434 RPVLVRQSTFIKEAPSP-TLRRKLEESASFESLSPSSRPASPTRSQAQTPVLSPSLPDMS 2492
             PV    S      P P T       S+ F     S+ P + T  +  T   +PS P  +
Sbjct: 1556 TPVAHTNSATSSRPPPPFTTHSPPTGSSPFS----STGPMTATSFKTTTTYPTPSHPQTT 1611

Query: 2493 LSTHSSVQAGGWRKLPPNLSPTIEYNDGRPAKRHDIARSHSESPSRLPINRSGTWKREHS 2552
            L TH          +PP  +  +      P+    I  +H++  +   I         HS
Sbjct: 1612 LPTH----------VPPFSTSLV-----TPSTHTVITPTHAQMATSASI---------HS 1647

Query: 2553 KHSSSLPRVSTWRRTGSS----SSILSASSESSEKAKSEDEKHVNSISGTKQSKENQVSA 2608
              + ++P  +T + TGS+    +  L+ S  S   +     K   S+     S  +  + 
Sbjct: 1648 MPTGTIPPPTTLKATGSTHTAPTMTLTTSGTSQALSSLNTAKTSTSLHSHTSSTHHAEAT 1707

Query: 2609 KGTWRKIKENEFS--------PTNSTSQTVSSGATNGAESKTLIYQMAPAVSKTEDVWVR 2660
              +   I  N  S         T+ TSQ+ SS +T  A++ T ++    +    E     
Sbjct: 1708 STSTTNITPNPTSTGTPPMTVTTSGTSQSRSSFST--AKTSTSLHSHTSSTHHPEVTSTS 1765

Query: 2661 IEDCPINNPRSG-RSPTGNTPPVIDSVSEKANPNIKDSKDNQAKQNVGNGSVPMRTVGLE 2719
                  N+  +G R+P  +T     + S    P    S           G+ P+ + G  
Sbjct: 1766 TTSITPNHTSTGTRTPVAHTTSA--TSSRLPTPFTTHSPP--------TGTTPISSTG-- 1813

Query: 2720 NRLNSFIQVDAPDQKGTEIKPGQNNP-------VP------VSETNESSIVERTPFSSSS 2766
                    V A   + T   P  ++P       VP      V+ +  + I+      ++S
Sbjct: 1814 -------PVTATSFQTTTTYPTPSHPHTTLPTHVPSFSTSLVTPSTHTVIIPTHTQMATS 1866

Query: 2767 SSKHSSPSGTV----AARVTPFNYNPSPRKSSADSTSARPSQIPT-------PVNNNTKK 2815
            +S HS P+GT+      + T   +   P   +   TS  PS   T       P + ++  
Sbjct: 1867 ASIHSMPTGTIPPPTTIKATGSTHTAPPMTPTTSGTSQSPSSFSTAKTSTSLPYHTSSTH 1926

Query: 2816 RDSKTDST--------ESSGTQSPKRHSGS 2837
                T ++         S+GT++P  H+ S
Sbjct: 1927 HPEVTPTSTTNITPKHTSTGTRTPVAHTTS 1956



 Score = 52.8 bits (125), Expect = 5e-06
 Identities = 126/608 (20%), Positives = 216/608 (35%), Gaps = 104/608 (17%)

Query: 2232 HIPGVRNSSSSTSPVSKKGPPLKTPASKSPSEGQTATTSPRGAKPSVKSELSPVARQTSQ 2291
            H P V  +S+ST+ ++   P   +  +++P    T+ TS R   P             S 
Sbjct: 1757 HHPEV--TSTSTTSIT---PNHTSTGTRTPVAHTTSATSSRLPTPFTTHSPPTGTTPISS 1811

Query: 2292 IGGSSKAPSRSGSRDSTPSRPAQQPLSRPIQSPGRNSISPGRNGISPPN--------KLS 2343
             G  +    ++ +   TPS P    L   + S   + ++P  + +  P          + 
Sbjct: 1812 TGPVTATSFQTTTTYPTPSHP-HTTLPTHVPSFSTSLVTPSTHTVIIPTHTQMATSASIH 1870

Query: 2344 QLPRTSSPSTASTKSSGSGKMSYTSPGRQMSQQNLTKQTGLSKNASSIPRSESASKGLNQ 2403
             +P  + P   + K++GS   ++T+P            T  +   S  P S S +K    
Sbjct: 1871 SMPTGTIPPPTTIKATGS---THTAP----------PMTPTTSGTSQSPSSFSTAKTSTS 1917

Query: 2404 MNNGNGANKKVELSRMSSTKSSGSESDRSER-PVLVRQSTFIKEAPSPTLRRKLEESASF 2462
            +     +    E++  S+T  +   +    R PV    S      P+P         +S 
Sbjct: 1918 LPYHTSSTHHPEVTPTSTTNITPKHTSTGTRTPVAHTTSASSSRLPTPFTTHSPPTGSSP 1977

Query: 2463 ESLSPSSRPASPTRSQAQTPVLSPSLPDMSLSTHSSVQAGGWRKLPPNLSPTIEYNDGRP 2522
             S   S+ P + T  Q  T   +PS P  +L TH          +PP  +  +      P
Sbjct: 1978 FS---STGPMTATSFQTTTTYPTPSHPQTTLPTH----------VPPFSTSLV-----TP 2019

Query: 2523 AKRHDIARSHSESPSRLPINRSGTWKREHSKHSSSLPRVSTWRRTGSSSSILSASSESSE 2582
            +    I  +H++  +   I         HS  + ++P  +T + TGS+ +    +     
Sbjct: 2020 STHTVIITTHTQMATSASI---------HSTPTGTVPPPTTLKATGSTHTAPPMTV---- 2066

Query: 2583 KAKSEDEKHVNSISGTKQSKENQVSAKGTWRKIKENEFSPTNSTSQTVSSGATNGAESKT 2642
                       + SGT Q+  +  +A  +   I  + + P NS+S+  SS  T       
Sbjct: 2067 -----------TTSGTSQTHSSFSTATASSSFISSSSWLPQNSSSRPPSSPITT------ 2109

Query: 2643 LIYQMAPAVSKTEDVWVRIEDCPINNPRSGRSPTGNTPPVIDSV--SEKANPNIKDSKDN 2700
               Q+    S T  V         N   S  SP+ + P  + S   S  ++P        
Sbjct: 2110 ---QLPHLSSATTPV------STTNQLSSSFSPSPSAPSTVSSYVPSSHSSPQTSSPSVG 2160

Query: 2701 QAKQNVGNGSVPMRTVGLENRLNSFIQVDAPDQKGTEIKPGQNNPVPVSETNESSIVERT 2760
             +   V   S P+ +  L +  +S +    P        P      P S    ++I    
Sbjct: 2161 TSSSFV---SAPVHSTTLSSGSHSSLSTH-PTTASVSASP----LFPSSPAASTTIRATL 2212

Query: 2761 PFSSSSSSKHSS--PSGTVAARVTPFNYNPSPRKSSADSTSARPSQIPTPVNNNTKKRDS 2818
            P + SS    S+  P  TV         +P+P    A ST A PS   T  + +T    S
Sbjct: 2213 PHTISSPFTLSALLPISTVTV-------SPTPSSHLASSTIAFPSTPRTTASTHTAPAFS 2265

Query: 2819 KTDSTESS 2826
               +T  S
Sbjct: 2266 SQSTTSRS 2273



 Score = 48.1 bits (113), Expect = 1e-04
 Identities = 148/779 (18%), Positives = 270/779 (34%), Gaps = 105/779 (13%)

Query: 2099 FDWKAIQEGANSIVSSLHQAAAAACLSRQASSDS-DSILSLKSGISLGSPFHLTP----- 2152
            F    +    +++++  H   A +  +  A + +     +LK+  S  +   +TP     
Sbjct: 1450 FSTSLVTPSTHTVITPTHAQMATSASNHSAPTGTIPPPTTLKATGSTHTAPPITPTTSGT 1509

Query: 2153 DQEEKPFTSNKGPRILKPGEKSTLETKKIESESKGIKGGKKVYKSLITGKVRSNSEISGQ 2212
             Q    F++NK P  L     ST   +   + +  I       ++  T    +NS  S +
Sbjct: 1510 SQAHSSFSTNKTPTSLHSHTSSTHHPEVTPTSTTTITPNPTSTRTR-TPVAHTNSATSSR 1568

Query: 2213 MKQPLQANMPSISRGRTMIHIPGVRNSSSSTSPVSKKGPPLKT-PASKSPSEGQTATTSP 2271
               P   + P           P    S  +T+       P  T P    P      T S 
Sbjct: 1569 PPPPFTTHSPPTGSSPFSSTGPMTATSFKTTTTYPTPSHPQTTLPTHVPPFSTSLVTPST 1628

Query: 2272 RGAKPSVKSELSPVARQTSQIGGSSKAPSRSGSRDSTPSRPAQQPLSRPIQSPGRNSISP 2331
                    ++++  A   S   G+   P+   +  ST + P    L+    S   +S++ 
Sbjct: 1629 HTVITPTHAQMATSASIHSMPTGTIPPPTTLKATGSTHTAPTMT-LTTSGTSQALSSLNT 1687

Query: 2332 GRNGISPPNKLSQLPRTSSPSTASTK------SSGSGKMSYTSPGRQMSQQNLTK---QT 2382
             +   S  +  S      + ST++T       S+G+  M+ T+ G   S+ + +     T
Sbjct: 1688 AKTSTSLHSHTSSTHHAEATSTSTTNITPNPTSTGTPPMTVTTSGTSQSRSSFSTAKTST 1747

Query: 2383 GLSKNASSIPRSESASKGLNQMN-NGNGANKKVELSRMSSTKSS-------------GSE 2428
             L  + SS    E  S     +  N      +  ++  +S  SS             G+ 
Sbjct: 1748 SLHSHTSSTHHPEVTSTSTTSITPNHTSTGTRTPVAHTTSATSSRLPTPFTTHSPPTGTT 1807

Query: 2429 SDRSERPVLVRQSTFIKEAPSP----TLRRKLEESASFESLSPSSRPAS-PTRSQAQTPV 2483
               S  PV           P+P    T       S S   ++PS+     PT +Q  T  
Sbjct: 1808 PISSTGPVTATSFQTTTTYPTPSHPHTTLPTHVPSFSTSLVTPSTHTVIIPTHTQMATSA 1867

Query: 2484 LSPSLPDMSLSTHSSVQAGGWRKLPPNLSPTIEYNDGRPAKRHDIARSHSESPSRLPINR 2543
               S+P  ++   ++++A G     P ++PT       P+     + S +++ + LP + 
Sbjct: 1868 SIHSMPTGTIPPPTTIKATGSTHTAPPMTPTTSGTSQSPS-----SFSTAKTSTSLPYHT 1922

Query: 2544 SGTWKREHSKHSSS--LPRVSTWRRTGSSSSILSASSESSEKAKSEDEKHVNSISGTKQS 2601
            S T   E +  S++   P+ ++   TG+ + +   +S SS +  +    H          
Sbjct: 1923 SSTHHPEVTPTSTTNITPKHTS---TGTRTPVAHTTSASSSRLPTPFTTH---------- 1969

Query: 2602 KENQVSAKGTWRKIKENEFSPTNSTSQTVSSGATNGAESKTLIYQMAPAVSKTEDVWVRI 2661
                               SP   +S   S+G       +T      P+  +T       
Sbjct: 1970 -------------------SPPTGSSPFSSTGPMTATSFQTTTTYPTPSHPQTT------ 2004

Query: 2662 EDCPINNPRSGRSPTGNTPPVIDSVSEKANPNIKDSKDNQAKQNVGNGSVPMRTVGLENR 2721
                         PT + PP   S+   +   +  +   Q   +    S P  TV     
Sbjct: 2005 ------------LPT-HVPPFSTSLVTPSTHTVIITTHTQMATSASIHSTPTGTVPPPTT 2051

Query: 2722 LNSFIQVD-APDQKGTEIKPGQNNPVPVSETNESSIVERTPF--SSSSSSKHSSPSGT-- 2776
            L +      AP    T     Q +    + T  SS +  + +   +SSS   SSP  T  
Sbjct: 2052 LKATGSTHTAPPMTVTTSGTSQTHSSFSTATASSSFISSSSWLPQNSSSRPPSSPITTQL 2111

Query: 2777 --VAARVTPFNYNPSPRKSSADSTSARPSQIPT--PVNNNTKKRDSKTDSTESSGTQSP 2831
              +++  TP +       S + S SA PS + +  P ++++ +  S +  T SS   +P
Sbjct: 2112 PHLSSATTPVSTTNQLSSSFSPSPSA-PSTVSSYVPSSHSSPQTSSPSVGTSSSFVSAP 2169



 Score = 33.9 bits (76), Expect = 2.4
 Identities = 75/344 (21%), Positives = 118/344 (34%), Gaps = 37/344 (10%)

Query: 2135 ILSLKSGISLGSPFHLTPDQEEKPFTSNKGPRILKPGEKSTLETKKIESESKGIKGGKKV 2194
            I++  + ++  +  H TP     P T+ K           T+ T                
Sbjct: 2025 IITTHTQMATSASIHSTPTGTVPPPTTLKATGSTHTAPPMTVTTSGTSQTHSSFSTATAS 2084

Query: 2195 YKSLITGKVRSNSEISGQMKQPLQANMPSISRGRTMIHIPGVRNSSSSTSPVSKKGPPLK 2254
               + +      +  S     P+   +P +S   T +      +SS S SP +       
Sbjct: 2085 SSFISSSSWLPQNSSSRPPSSPITTQLPHLSSATTPVSTTNQLSSSFSPSPSAPSTVSSY 2144

Query: 2255 TPASKSPSEGQTATTSPRGAKPSVKSELSPVARQTSQIGGSSKAPSRSGSRDSTPSRPAQ 2314
             P+S S         SP+ + PSV +  S V+        SS + S   +  +T S  A 
Sbjct: 2145 VPSSHS---------SPQTSSPSVGTSSSFVSAPVHSTTLSSGSHSSLSTHPTTASVSA- 2194

Query: 2315 QPL--SRPIQSPGRNSISPGRNGISPPNKLSQLPRTSSPSTASTKSSGSGKMSYTSPGRQ 2372
             PL  S P  S    +  P  + IS P  LS L   S+ + + T SS     +   P   
Sbjct: 2195 SPLFPSSPAASTTIRATLP--HTISSPFTLSALLPISTVTVSPTPSSHLASSTIAFPS-- 2250

Query: 2373 MSQQNLTKQTGLSKNASSIPRSESASKGLNQMNNGNGANKKVELSRMSSTKSSGSESDRS 2432
                  T +T  S + +    S+S +      +       +V  S   S  S  +    S
Sbjct: 2251 ------TPRTTASTHTAPAFSSQSTT------SRSTSLTTRVPTSGFVSLTSGVTGIPTS 2298

Query: 2433 ERPVLVRQSTFIKEAPSPTL---RRKLEESASFESLSPSSRPAS 2473
              PV    +      P PTL    R L  S +    +P+S P S
Sbjct: 2299 --PV----TNLTTRHPGPTLSPTTRFLTSSLTAHGSTPASAPVS 2336


>gi|50083281 KIAA1853 protein [Homo sapiens]
          Length = 611

 Score = 65.1 bits (157), Expect = 1e-09
 Identities = 122/516 (23%), Positives = 195/516 (37%), Gaps = 78/516 (15%)

Query: 2189 KGGKKVYKSLITGKVRSNSEISGQMKQPLQANMPSISRGRTMIHIPGVRNSSSSTSPVSK 2248
            +G KK  KS    + RS+S     +K+  + +     R R+       +   SS+SP SK
Sbjct: 107  RGKKKKKKSTRKKRRRSSSYSPSPVKKKKKKSSKKHKRRRSF----SKKRRHSSSSPKSK 162

Query: 2249 KGPPLK-TPASKSPSEGQTATTSPRGAKPSVKSELSPVARQTSQIGGSSKAPSRSGSRDS 2307
            +    +    S+S           R    S  SE  P + ++   G S +   +S  R S
Sbjct: 163  RRDEKRHKKQSRSRPRKSHRHRHHRCPSRSQSSESRPSSCESRHRGRSPEEGQKSRRRHS 222

Query: 2308 ----------TPSRPAQQPLSRPIQSPGRNSISPGRNGISPPNKLSQL-PRTSSPSTAST 2356
                      +P   + +P S+P+Q  G  S    R  I+     + L  +T+SP T S 
Sbjct: 223  RRCSKTLCKDSPEAQSSRPPSQPLQMLGYLS---ARGVITGSGSAADLFTKTASPLTTSR 279

Query: 2357 KSS---------GSGKMSYTSPGRQMSQQNLTKQTGLSKNASSIPRSESASKGLNQMNNG 2407
              S          S   + TS  R   Q+  +   GLSK+      S + S   N     
Sbjct: 280  GRSQEYDSGNDTSSPPSTQTSSARSRGQEKGSPSGGLSKSREL--NSGNTSDSGNSFTTS 337

Query: 2408 NGANKKVELSRMSSTKSSGSESDRSERPVL----VRQSTFIKEAPSPTLRRKLEESASFE 2463
            +  NK   L  +S T S G ES   + P L    V++S+ +      +  +    S+S+ 
Sbjct: 338  SPQNKGAMLENLSPT-SRGRESRGFQSPCLECAEVKKSSLVPSTARSSPMKGCSRSSSYA 396

Query: 2464 SL---SPSSRPASPTRSQAQTPVLSPSLPDMSLSTHSSVQAGGWRKLPPNLSP----TIE 2516
            S    S SSR  +P  S   T   S S    S S   S  +   ++ PP+ S     +  
Sbjct: 397  STRSSSHSSRSPNPRASPRYTQSRSTSSEKRSYSRSPSYSSKSGKRSPPSRSSRSRRSPS 456

Query: 2517 YNDGRPAKRHDIA------------------RSHS-------ESPSRLPINRSGT----- 2546
            Y+   P++  D                    RS+S       +SPS L   R  +     
Sbjct: 457  YSRYSPSRERDPKYSEKDSQQRERERARRRRRSYSPMRKRRRDSPSHLEARRITSARKRP 516

Query: 2547 --WKREHSKHSSSLPRVSTWRRTGSSSSILSASSESSEKAKSEDEKHVNSISGTKQSKEN 2604
              + R     S SL   S+W    SSSS   ++S S  +++S       S + T  S  +
Sbjct: 517  IPYYRPSPSSSGSLSSTSSWY--SSSSS--RSASRSYSRSRSRSRSRRRSRTRTSSSSSS 572

Query: 2605 QVSAKGTWRKIKENEFSPTNSTSQTVSSGATNGAES 2640
            +  + G+  + +    S + S SQ+ S  + +   S
Sbjct: 573  RSPSPGSRSRSRSRSRSRSRSRSQSRSYSSADSYSS 608



 Score = 48.1 bits (113), Expect = 1e-04
 Identities = 72/323 (22%), Positives = 121/323 (37%), Gaps = 28/323 (8%)

Query: 2183 SESKGIKGGKKVYKSLITGKVRSNSEISGQMKQPLQANMPSISRGRTMIHIPGVRNSSSS 2242
            S S G+   +++     +    S +  S Q K  +  N+   SRGR      G ++    
Sbjct: 311  SPSGGLSKSRELNSGNTSDSGNSFTTSSPQNKGAMLENLSPTSRGRES---RGFQSPCLE 367

Query: 2243 TSPVSKKGPPLKTPASKSPSEGQTATTSPRGAKPSVKSELSPVARQTSQIGGSSKAPSRS 2302
             + V KK   + + A  SP +G + ++S    + S  S  SP  R + +   S    S  
Sbjct: 368  CAEV-KKSSLVPSTARSSPMKGCSRSSSYASTRSSSHSSRSPNPRASPRYTQSRSTSSEK 426

Query: 2303 GSRDSTPSRPAQQPLSRPIQSPGRNSISPGRNGISPPNKLSQLPRTSSPSTASTKSSGSG 2362
             S   +PS  ++     P     R+  SP  +  SP  +               + +   
Sbjct: 427  RSYSRSPSYSSKSGKRSPPSRSSRSRRSPSYSRYSPSRERDPKYSEKDSQQRERERARRR 486

Query: 2363 KMSYT--SPGRQMSQQNLTKQTGLSKNASSIP---RSESASKGLNQMNNGNGANKKVELS 2417
            + SY+     R+ S  +L  +   S     IP    S S+S  L+  ++   ++     S
Sbjct: 487  RRSYSPMRKRRRDSPSHLEARRITSARKRPIPYYRPSPSSSGSLSSTSSWYSSSSSRSAS 546

Query: 2418 RMSSTKSSGSESDRSERPVLVRQSTFIKEAPSPTLRRKLEESASFESLSPSSRPASPTRS 2477
            R  S   S S S R                     R +   S+S  S SP SR  S +RS
Sbjct: 547  RSYSRSRSRSRSRRRS-------------------RTRTSSSSSSRSPSPGSRSRSRSRS 587

Query: 2478 QAQTPVLSPSLPDMSLSTHSSVQ 2500
            ++++   S S    S  ++SS +
Sbjct: 588  RSRSRSRSQSRSYSSADSYSSTR 610



 Score = 40.4 bits (93), Expect = 0.025
 Identities = 120/600 (20%), Positives = 224/600 (37%), Gaps = 79/600 (13%)

Query: 2256 PASKSPSE--GQTATTSPRGAKPSVKSELSPVARQTSQIGGSSKAPSRSGSRDSTP--SR 2311
            PA   PSE  GQ   T P G     + +       T +  G+++  S S  +D TP  S 
Sbjct: 54   PAQDGPSEKLGQHLATEPLGTNSWERDK-------TCRELGATRGHSASHDKDLTPPPSS 106

Query: 2312 PAQQPLSRPIQSPGRNSISPGRNGISPPNKLSQLPR-------------TSSPSTASTKS 2358
              ++   +  +   R S S   + +    K S                 +SSP +     
Sbjct: 107  RGKKKKKKSTRKKRRRSSSYSPSPVKKKKKKSSKKHKRRRSFSKKRRHSSSSPKSKRRDE 166

Query: 2359 SGSGKMSYTSPGRQMSQQNLTKQTGLSKNASSIPRS-ESASKGLNQMNNGNGANKKVELS 2417
                K S + P R+  +    +    S+++ S P S ES  +G +        +++    
Sbjct: 167  KRHKKQSRSRP-RKSHRHRHHRCPSRSQSSESRPSSCESRHRGRSPEEGQK--SRRRHSR 223

Query: 2418 RMSSTKSSGSESDRSERPVLVRQSTFIKEAPSPTLRRKLEESASFESL-SPSSRPASPTR 2476
            R S T    S   +S RP     S  ++     + R  +  S S   L + ++ P + +R
Sbjct: 224  RCSKTLCKDSPEAQSSRP----PSQPLQMLGYLSARGVITGSGSAADLFTKTASPLTTSR 279

Query: 2477 SQAQTPVLSPSLPDMSLSTHSSVQAGGWRKLPPN--LSPTIEYNDGRPAKR-HDIARSHS 2533
             ++Q             +  SS ++ G  K  P+  LS + E N G  +   +    S  
Sbjct: 280  GRSQEYDSGNDTSSPPSTQTSSARSRGQEKGSPSGGLSKSRELNSGNTSDSGNSFTTSSP 339

Query: 2534 ESPSRLPINRSGTWKREHSKHSSSLPRVSTWRRTGSSSSILSASSESSEKAKSEDEKHVN 2593
            ++   +  N S T +   S+   S P +        SS + S +  S  K  S    + +
Sbjct: 340  QNKGAMLENLSPTSRGRESRGFQS-PCLEC-AEVKKSSLVPSTARSSPMKGCSRSSSYAS 397

Query: 2594 SISGTKQSKENQVSAKGTWRKIKENEFSPTNSTSQTVSSGATNGAESKTLIYQMAPAVSK 2653
            + S +  S+                  SP    S   +   +  +E ++  Y  +P+ S 
Sbjct: 398  TRSSSHSSR------------------SPNPRASPRYTQSRSTSSEKRS--YSRSPSYSS 437

Query: 2654 TEDVWVRIEDCPINNPRSGRSPTGNTPPVIDSVSEKANPNIKDSKDNQAKQNVGNGSVPM 2713
                       P  + RS RSP+ +          K +      ++ +  +       PM
Sbjct: 438  KSGK----RSPPSRSSRSRRSPSYSRYSPSRERDPKYSEKDSQQRERERARRRRRSYSPM 493

Query: 2714 RTVGLENRLNSFIQVDAPDQKGTEIKPGQNNPVPV---SETNESSIVERTPFSSSSSSKH 2770
            R    + R +S   ++A       I   +  P+P    S ++  S+   + + SSSSS+ 
Sbjct: 494  R----KRRRDSPSHLEA-----RRITSARKRPIPYYRPSPSSSGSLSSTSSWYSSSSSRS 544

Query: 2771 SSPSGTVAARVTPFNYNPSPRKSSADSTSARPSQIPTPVNNNTKKRDSKTDSTESSGTQS 2830
            +S S + +      + + S R+S   ++S+  S+ P+P + +  +  S++ S   S ++S
Sbjct: 545  ASRSYSRSR-----SRSRSRRRSRTRTSSSSSSRSPSPGSRSRSRSRSRSRSRSRSQSRS 599



 Score = 35.8 bits (81), Expect = 0.62
 Identities = 137/618 (22%), Positives = 208/618 (33%), Gaps = 127/618 (20%)

Query: 1767 GKKKKPTSPVKPIPQNTEYRTRVRKNADSKNNLNAERVFSDNKDSKKQNLKNNSKVFNDK 1826
            GKKKK  S  K   +++ Y     K    K++   +R  S +K  +  +    SK  ++K
Sbjct: 108  GKKKKKKSTRKKRRRSSSYSPSPVKKKKKKSSKKHKRRRSFSKKRRHSSSSPKSKRRDEK 167

Query: 1827 LPNNEDRVRGSFAFDSPHHYTPIEGTPYCFSRNDSLSSLDFDDDDVDLSREKAELRKAKE 1886
                + R R   +    HH  P        SR+ S  S     +     R   E +K++ 
Sbjct: 168  RHKKQSRSRPRKSHRHRHHRCP--------SRSQSSESRPSSCESRHRGRSPEEGQKSRR 219

Query: 1887 NKESEAKVTSHTELTSNQQSANKTQAIAKQPINRGQPKPILQKQSTFPQSSKDIPDRGAA 1946
                      H+   S     +  +A + +P +  QP  +L   S    +   I   G+A
Sbjct: 220  R---------HSRRCSKTLCKDSPEAQSSRPPS--QPLQMLGYLS----ARGVITGSGSA 264

Query: 1947 TDEKLQNFAIENTPVCFSHNSSLSSLSDIDQENNNKENEPIKETEPPDSQGEPSKPQASG 2006
             D     F    +P+  S   S    S      N+  + P  +T    S+G+  K   SG
Sbjct: 265  ADL----FTKTASPLTTSRGRSQEYDS-----GNDTSSPPSTQTSSARSRGQ-EKGSPSG 314

Query: 2007 YAPKSFHVEDTPVCFSRNSSLSSLSIDSEDDLLQECISSAMPKKKKPSRLKGDNEKHSPR 2066
               KS  +       S NS  +S                                  SP+
Sbjct: 315  GLSKSRELNSGNTSDSGNSFTTS----------------------------------SPQ 340

Query: 2067 NMGGILGEDLTLDLKDIQRPDSEHGLSPDSENFDWKAIQ----EGANSIVSSLHQAAAAA 2122
            N G +L                   LSP S   + +  Q    E A    SSL  + A +
Sbjct: 341  NKGAML-----------------ENLSPTSRGRESRGFQSPCLECAEVKKSSLVPSTARS 383

Query: 2123 CLSRQASSDSDSILSLKSGISLGSPFHLTPDQEEKPFTSNKGPRILKPGEKSTLETKKIE 2182
               +  S  S    +  S  S  SP                 PR  +    S+ +     
Sbjct: 384  SPMKGCSRSSSYASTRSSSHSSRSP------------NPRASPRYTQSRSTSSEKRSYSR 431

Query: 2183 SESKGIKGGKKVYKSLITGKVRSNSEIS---GQMKQPLQANMPSISRGRTMIHIPGVRNS 2239
            S S   K GK+   S  +   RS S       + + P  +   S  R R        R  
Sbjct: 432  SPSYSSKSGKRSPPSRSSRSRRSPSYSRYSPSRERDPKYSEKDSQQRERER-----ARRR 486

Query: 2240 SSSTSPVSKKGPPLKTPASKSPS--EGQTATTSPRGA----KPSVKSELSPVARQTSQIG 2293
              S SP+ K+          SPS  E +  T++ +      +PS  S  S  +  +    
Sbjct: 487  RRSYSPMRKR-------RRDSPSHLEARRITSARKRPIPYYRPSPSSSGSLSSTSSWYSS 539

Query: 2294 GSSKAPSRSGSRDSTPSRPAQQPLSRPIQSPGRNSISPGRNGISPPNKLSQLPRTSSPST 2353
             SS++ SRS SR  + SR  ++  +R   S    S SPG    S     S   R+ S S 
Sbjct: 540  SSSRSASRSYSRSRSRSRSRRRSRTRTSSSSSSRSPSPGSRSRSRSRSRS---RSRSRSQ 596

Query: 2354 ASTKSSGSGKMSYTSPGR 2371
            + + SS     SY+S  R
Sbjct: 597  SRSYSSAD---SYSSTRR 611



 Score = 35.0 bits (79), Expect = 1.1
 Identities = 42/193 (21%), Positives = 74/193 (38%), Gaps = 32/193 (16%)

Query: 1189 SSQKQSFSFSKSSSGQSSKTEHMSSSSENTSTPS------------------------SN 1224
            SS+K+S+S S S S +S K    S SS +  +PS                          
Sbjct: 423  SSEKRSYSRSPSYSSKSGKRSPPSRSSRSRRSPSYSRYSPSRERDPKYSEKDSQQRERER 482

Query: 1225 AKRQNQLHPSSAQSRSGQPQKAATCKVSSINQETIQTYCVEDTPICFSRCSSLSSLSSAE 1284
            A+R+ + +    + R   P      +++S  +  I  Y    +P      SS SS  S+ 
Sbjct: 483  ARRRRRSYSPMRKRRRDSPSHLEARRITSARKRPIPYY--RPSPSSSGSLSSTSSWYSSS 540

Query: 1285 DEIGCNQTTQEADSANTLQIAEIKEKIGTRSAEDPVSEVPAVSQHPRTKS-SRLQGSSLS 1343
                 +++   + S      +  + +  TR++    S  P+     R++S SR +  S S
Sbjct: 541  SSRSASRSYSRSRSR-----SRSRRRSRTRTSSSSSSRSPSPGSRSRSRSRSRSRSRSRS 595

Query: 1344 SESARHKAVEFSS 1356
               +   A  +SS
Sbjct: 596  QSRSYSSADSYSS 608



 Score = 34.7 bits (78), Expect = 1.4
 Identities = 54/216 (25%), Positives = 82/216 (37%), Gaps = 51/216 (23%)

Query: 810 RSDNFNTGNMTVLSPYLNTTVLPSSSSSRGSLDSSRSEKDRSLERERGIGLGNYHPATE- 868
           RS  +++GN T   P   T    SS+ SRG              +E+G   G    + E 
Sbjct: 281 RSQEYDSGNDTSSPPSTQT----SSARSRG--------------QEKGSPSGGLSKSREL 322

Query: 869 NPGTSSKRGLQISTTAAQIAKVM-EEVSAIHTSQEDRSSGSTTELHCVTDERNALRRSSA 927
           N G +S  G   +T++ Q    M E +S     +E R   S   L C   ++++L  S+A
Sbjct: 323 NSGNTSDSGNSFTTSSPQNKGAMLENLSPTSRGRESRGFQSPC-LECAEVKKSSLVPSTA 381

Query: 928 AHT------HSNTYNFTKSENSNRTCSMPYAKLEY--KRSSNDSLNSVSSSDGYG-KRGQ 978
             +       S++Y  T+S + +     P A   Y   RS++    S S S  Y  K G+
Sbjct: 382 RSSPMKGCSRSSSYASTRSSSHSSRSPNPRASPRYTQSRSTSSEKRSYSRSPSYSSKSGK 441

Query: 979 MKPSIES---------------------YSEDDESK 993
             P   S                     YSE D  +
Sbjct: 442 RSPPSRSSRSRRSPSYSRYSPSRERDPKYSEKDSQQ 477



 Score = 32.7 bits (73), Expect = 5.2
 Identities = 32/110 (29%), Positives = 45/110 (40%), Gaps = 9/110 (8%)

Query: 1146 RYSEEE-QHEEEERPTNYSIKYNE-EKRHVDQPIDYSLKYATDIPSSQKQSFSFSKSSSG 1203
            +YSE++ Q  E ER       Y+   KR  D P     +  T         +  S SSSG
Sbjct: 469  KYSEKDSQQRERERARRRRRSYSPMRKRRRDSPSHLEARRITSARKRPIPYYRPSPSSSG 528

Query: 1204 QSSKTEHMSSSSENTSTPSSNAKRQNQLHPSSAQSRSGQPQKAATCKVSS 1253
              S T    SSS + S   S ++       S ++SRS +  +  T   SS
Sbjct: 529  SLSSTSSWYSSSSSRSASRSYSR-------SRSRSRSRRRSRTRTSSSSS 571



 Score = 32.3 bits (72), Expect = 6.9
 Identities = 116/588 (19%), Positives = 198/588 (33%), Gaps = 107/588 (18%)

Query: 2313 AQQPLSRPIQSPGRNSISPGRNGISPPNKLSQLPRTSSPSTASTKSSGSGKMSYTSPGRQ 2372
            A++PL R    P  N + P ++G  P  KL Q   T    T S +               
Sbjct: 38   ARKPLPRT--EPQNNPVVPAQDG--PSEKLGQHLATEPLGTNSWE--------------- 78

Query: 2373 MSQQNLTKQTGLSKNASSIPRSESASKGLNQMNNGNGANKKVELSRMSSTKSSGSESDRS 2432
              +    ++ G ++  S+     S  K L    +  G  KK + +R    +SS      S
Sbjct: 79   --RDKTCRELGATRGHSA-----SHDKDLTPPPSSRGKKKKKKSTRKKRRRSSSY----S 127

Query: 2433 ERPVLVRQSTFIKEAPSPTLRRKLEESASFESLSPSSRPASPTRSQAQT---PVLS---- 2485
              PV  ++    K +     RR   +     S SP S+     R + Q+   P  S    
Sbjct: 128  PSPVKKKKK---KSSKKHKRRRSFSKKRRHSSSSPKSKRRDEKRHKKQSRSRPRKSHRHR 184

Query: 2486 ----PSLPDMSLSTHSSVQAGGWRKLPPNLSPTIEYNDGRPAKR--HDIARSHSESPSRL 2539
                PS    S S  SS ++    + P     +   +  R +K    D   + S  P   
Sbjct: 185  HHRCPSRSQSSESRPSSCESRHRGRSPEEGQKSRRRHSRRCSKTLCKDSPEAQSSRPPSQ 244

Query: 2540 PINRSGTWKREHSKHSSSLPRVSTWRRTGSSSSILSASSESSEKAKSEDEKHVNSISGTK 2599
            P+   G +       + S      + +T S  +     S+  +             S  +
Sbjct: 245  PLQMLG-YLSARGVITGSGSAADLFTKTASPLTTSRGRSQEYDSGNDTSSPPSTQTSSAR 303

Query: 2600 QSKENQVSAKGTWRKIKENEFSPTNSTSQTVSSGATNGAESK-TLIYQMAPA-------- 2650
               + + S  G   K +E     + +TS + +S  T+  ++K  ++  ++P         
Sbjct: 304  SRGQEKGSPSGGLSKSRELN---SGNTSDSGNSFTTSSPQNKGAMLENLSPTSRGRESRG 360

Query: 2651 ----------VSKTEDVWVRIEDCPI-------------NNPRSGRSPTGNTPPVIDSVS 2687
                      V K+  V       P+             ++  S RSP     P      
Sbjct: 361  FQSPCLECAEVKKSSLVPSTARSSPMKGCSRSSSYASTRSSSHSSRSPNPRASPRYTQSR 420

Query: 2688 EKANPNIKDSKDNQAKQNVGNGSVPMRTVGLENRLNSFIQVDAPDQKGTEIKPGQNNPVP 2747
              ++     S+        G  S P R+    +R +      +P +   E  P  +    
Sbjct: 421  STSSEKRSYSRSPSYSSKSGKRSPPSRSS--RSRRSPSYSRYSPSR---ERDPKYSEKDS 475

Query: 2748 VSETNESSIVERTPFSSSSSSKHSSPSGTVAARVT-------PFNYNPSPRK-------- 2792
                 E +   R  +S     +  SPS   A R+T       P+ Y PSP          
Sbjct: 476  QQRERERARRRRRSYSPMRKRRRDSPSHLEARRITSARKRPIPY-YRPSPSSSGSLSSTS 534

Query: 2793 ---SSADSTSARPSQIPTPVNNNTKKRDSKTDSTESSGTQSPKRHSGS 2837
               SS+ S SA  S   +   + +++R S+T ++ SS ++SP   S S
Sbjct: 535  SWYSSSSSRSASRSYSRSRSRSRSRRR-SRTRTSSSSSSRSPSPGSRS 581


>gi|115298682 HBxAg transactivated protein 2 [Homo sapiens]
          Length = 2817

 Score = 62.4 bits (150), Expect = 6e-09
 Identities = 131/615 (21%), Positives = 219/615 (35%), Gaps = 86/615 (13%)

Query: 2253 LKTPASKSPSEGQTATTSPRGAKPSVKSELSPVARQTSQIGGSSKAPSRSGSRDST-PSR 2311
            ++ P S    +G T   S +  K     E      Q  Q+     A  +  S+ S  P R
Sbjct: 1669 IEDPQSNLNDDGFTEVVSKKQQKRLQDEERRKKEEQVIQVWNKKNANEKGRSQTSKLPPR 1728

Query: 2312 PAQQPLSRPIQSPGRNSISPGRNGISPPNKLSQLPRTSSPSTASTKSSGSGKMSYTSPGR 2371
             A++  +   Q+    S+ P  +   PP+  + +P ++S    +T +      S   P  
Sbjct: 1729 FAKKQATGIQQAQSSASVPPLASAPLPPSTSASVPASTSAPLPATLTPVPASTSAPVPAS 1788

Query: 2372 QMSQQNLTKQTGLSKNASSIPRSESASKGLNQMNNGNGANKKVELSRMSSTKSSGSESDR 2431
             ++         L+  ++ +P S  A    +   +   A+     S  + T SS   S  
Sbjct: 1789 TLAPV-------LASTSAPVPASPLAPVSASASVS---ASVPASTSAAAITSSSAPASAP 1838

Query: 2432 SERPVLVRQST-----FIKEAPSPTLRRKLEESASFESLSPSSRPASPTRSQAQTPVLSP 2486
            +  P+L   ST      +  A  P L   L  +++      +S PA+P  +    P  +P
Sbjct: 1839 APTPILASVSTPASVTILASASIPILASALASTSAPTPAPAASSPAAPVITAPTIPASAP 1898

Query: 2487 SLPDMSLSTHSSVQAGGWRKLPPNLSPTIEYNDGRPAKRHDIARSHSESPSRLPINRSGT 2546
            +         +S  A       P  +P    N   PA     A++H   P + P+  +  
Sbjct: 1899 TASVPLAPASASAPA-------PAPTPVSAPNPAPPAPAQTQAQTHK--PVQNPLQTTSQ 1949

Query: 2547 WKREHSKHSSSLPRVSTWRRT---GSSSSILSASSESSEKAKSEDEKHVNSISGTKQSKE 2603
              ++    S  LP   T   T    S  SI +  S  +  A+  D K          SK+
Sbjct: 1950 SSKQPPP-SIRLPSAQTPNGTDYVASGKSIQTPQSHGTLTAELWDNKVAPPAVLNDISKK 2008

Query: 2604 ------NQVSAKGTWRKIKENEFSPTNSTSQTVSSGATNGAESKTLIYQMAPAVSKTEDV 2657
                   Q  +   W K        T+  S   S GA NG ES                +
Sbjct: 2009 LGPISPPQPPSVSAWNK------PLTSFGSAPSSEGAKNGQES---------------GL 2047

Query: 2658 WVRIEDCPINNPRSGRSPTGNTPPVIDSVSEKANPNIKDSKDNQAKQ------------- 2704
             +  +      P S     GN   V+  +SEK+   I + K+ + KQ             
Sbjct: 2048 EIGTDTIQFGAPASN----GNENEVVPVLSEKSADKIPEPKEQRQKQPRAGPIKAQKLPD 2103

Query: 2705 --NVGNGSVPMRTVGLENRLNSFIQVDAPDQKGTEIKP-GQNNPVPVSETNESSIVERTP 2761
               V N       +G E  L +    DA      +++P GQ  P P +  +   +   T 
Sbjct: 2104 LSPVENKEHKPGPIGKERSLKNRKVKDA-----QQVEPEGQEKPSPATVRSTDPV---TT 2155

Query: 2762 FSSSSSSKHSSPSGTVAARVTPFNYNPSPRKSSADSTSARPSQIPTPVNNNTKKRDSKTD 2821
              + + S+ S+  GT+ + V+   Y  + ++S  D T+   S   T   NNTK  D+  +
Sbjct: 2156 KETKAVSEMSTEIGTMIS-VSSAEYGTNAKESVTDYTTPSSSLPNTVATNNTKMEDTLVN 2214

Query: 2822 STESSGT-QSPKRHS 2835
            +     T   PKR +
Sbjct: 2215 NVPLPNTLPLPKRET 2229



 Score = 46.6 bits (109), Expect = 4e-04
 Identities = 198/993 (19%), Positives = 344/993 (34%), Gaps = 171/993 (17%)

Query: 1103 RSRGANGSETNRVGSNHGINQNVSQSLCQEDDYEDDKPTNYSERYSEEEQHEEEERPTNY 1162
            R   +  +E   V +N  +N    + +    D   +K  + S + S ++ +EE E  +  
Sbjct: 1443 REAASKSNEVVAVPTNGTVNNVAQEPVNTLGDISGNKTPDLSNQNSSDQANEEWETASES 1502

Query: 1163 SIKYNE-----EKRHVDQPIDYSLKYATDI--PSSQ--KQSFSFSKSSSGQSSKTEHMSS 1213
            S  +NE     EK++ D      +K   ++  P  +  K+SFS  +    Q+ +  +   
Sbjct: 1503 S-DFNERRERDEKKNADLNAQTVVKVGENVLPPKREIAKRSFSSQRPVDRQNRRGNNGPP 1561

Query: 1214 SSENTSTPSSNAKRQNQLHPSSAQSRSG--QPQKAATCKVSSINQETIQTYCVEDTPICF 1271
             S    +   N +R     P S   + G    Q A T  V  IN  +   +  E  P   
Sbjct: 1562 KSGRNFSGPRNERRSG---PPSKSGKRGPFDDQPAGTTGVDLINGSS--AHHQEGVPNGT 1616

Query: 1272 SRCSSLSSLSSAEDEI--GCNQTTQEADSA------NTLQIAEIKEKIGTRSAEDPVSEV 1323
             + +S  S     ++   G  +  ++ D+       N   +  I +       EDP S +
Sbjct: 1617 GQKNSKDSTGKKREDPKPGPKKPKEKVDALSQFDLNNYASVVIIDDHPEVTVIEDPQSNL 1676

Query: 1324 PAVSQHPRTKSSRLQGSSLSSESARHK---AVEFSSGAKSPSKSGAQTPKSPPEHYVQET 1380
                       S+ Q   L  E  R K    ++  +   +  K  +QT K PP  + ++ 
Sbjct: 1677 N--DDGFTEVVSKKQQKRLQDEERRKKEEQVIQVWNKKNANEKGRSQTSKLPPR-FAKKQ 1733

Query: 1381 PLMFSRCTSVSSLDSFESRSIASSVQ-------SEPCSGMVSGIISPSDLPDSPGQTMPP 1433
                 +  S +S+    S  +  S         S P    ++ + + +  P  P  T+ P
Sbjct: 1734 ATGIQQAQSSASVPPLASAPLPPSTSASVPASTSAPLPATLTPVPASTSAP-VPASTLAP 1792

Query: 1434 SRSKTPPPPPQT--------AQTKREVPKNKAPTAEKRESGPKQAAVNAAVQRVQVLPDA 1485
              + T  P P +        A     VP + +  A    S P  A     +      P +
Sbjct: 1793 VLASTSAPVPASPLAPVSASASVSASVPASTSAAAITSSSAPASAPAPTPILASVSTPAS 1852

Query: 1486 DTLL----------HFATESTPDGFSCSSSLSALSLDEPFIQKDVELRIMPPVQENDNGN 1535
             T+L            A+ S P     +SS +A  +  P I        +P    + +  
Sbjct: 1853 VTILASASIPILASALASTSAPTPAPAASSPAAPVITAPTIPASAPTASVPLAPASASAP 1912

Query: 1536 ETESEQPKESNENQEKEAEKTIDSEKDLLDDSDDDDIEILEECIISAMPTKSSRKAKKPA 1595
                      N      A+    + K +                            + P 
Sbjct: 1913 APAPTPVSAPNPAPPAPAQTQAQTHKPV----------------------------QNPL 1944

Query: 1596 QT---ASKLPPPVARKPS-QLP--VYKLLPSQNRLQPQKHVSFTP--GDDMPRVYCVEGT 1647
            QT   +SK PPP  R PS Q P     +   ++   PQ H + T    D+      V   
Sbjct: 1945 QTTSQSSKQPPPSIRLPSAQTPNGTDYVASGKSIQTPQSHGTLTAELWDNK-----VAPP 1999

Query: 1648 PINFSTATSLSDLTIESPPNELA------------AGEGVRGGAQSGEFEKRDTI----P 1691
             +    +  L  ++   PP+  A            + EG + G +SG     DTI    P
Sbjct: 2000 AVLNDISKKLGPISPPQPPSVSAWNKPLTSFGSAPSSEGAKNGQESGLEIGTDTIQFGAP 2059

Query: 1692 TEGRSTDEAQG--GKTSSVTIPELDDNKAEE---GDILAECINSAMP-KGKSHKPFRVKK 1745
                + +E      + S+  IPE  + + ++   G I A+ +    P + K HKP  + K
Sbjct: 2060 ASNGNENEVVPVLSEKSADKIPEPKEQRQKQPRAGPIKAQKLPDLSPVENKEHKPGPIGK 2119

Query: 1746 IMDQVQQASASSSAPNKNQLDGKKKKPTSPVKPIP---QNTEYRTRVRKNADSKNNLNAE 1802
                        S  N+   D ++ +P    KP P   ++T+  T     A S+ +    
Sbjct: 2120 ----------ERSLKNRKVKDAQQVEPEGQEKPSPATVRSTDPVTTKETKAVSEMSTEIG 2169

Query: 1803 RVFSDNKDSKKQNLKNNSKVF---NDKLPN----NEDRVRGSFAFDSPHHYTPIEGTPYC 1855
             + S +      N K +   +   +  LPN    N  ++  +   + P   T        
Sbjct: 2170 TMISVSSAEYGTNAKESVTDYTTPSSSLPNTVATNNTKMEDTLVNNVPLPNTLPLPKRET 2229

Query: 1856 FSRNDSLSSLDFDDDDVDLSREKAELRKAKEN----KESEAKVTSH--------TELTSN 1903
              ++ SL+S+      +    E A  RKA EN    +E  + VTS         +   S 
Sbjct: 2230 IQQSSSLTSVPPTTFSLTFKMESA--RKAWENSPNVREKGSPVTSTAPPIATGVSSSASG 2287

Query: 1904 QQSAN----KTQAIAKQPINRGQPKPILQKQSTFPQSS--------KDIPDRGAATDEKL 1951
              +AN     + ++ + P+    P   L    T+  SS         D P+      ++L
Sbjct: 2288 PSTANYNSFSSASMPQIPVASVTPTASLSGAGTYTTSSLSTKSTTTSDPPNICKVKPQQL 2347

Query: 1952 QNFAIENTPVCFSHNSSLSSL-SDIDQENNNKE 1983
            Q  ++ +     SH S LS + S I Q+  N +
Sbjct: 2348 QTSSLPSA----SHFSQLSCMPSLIAQQQQNPQ 2376



 Score = 42.0 bits (97), Expect = 0.009
 Identities = 55/275 (20%), Positives = 104/275 (37%), Gaps = 39/275 (14%)

Query: 1397 ESRSIASSVQSEPCSGMVSGIISPSDLPDSPGQTMPPSR---SKTPPPPPQTAQT----- 1448
            E++     V +   S  +    S + +P   G +    R   S  PPPP   AQ      
Sbjct: 362  ENKKETDEVSNTKSSSQIPAQPSVAKVPYGKGPSFNQERGTSSHLPPPPKLLAQQHPPPD 421

Query: 1449 KREVPKNKAPTAEKRESGPK----------QAAVNAAVQRVQVLPDADTLLHFATESTPD 1498
            ++ VP    P   K++   +          Q+ ++AAV+R +   + +            
Sbjct: 422  RQAVPGRPGPFPSKQQVADEDEIWKQRRRQQSEISAAVERARKRREEEERRMEEQRKA-- 479

Query: 1499 GFSCSSSLSALSLDEPFIQKDV---ELRIMPPVQENDNGNETESEQPKESNENQEKEAEK 1555
              +C+  L  L      ++K     E+R     +E +   E E EQ +E  + +EK+ E+
Sbjct: 480  --ACAEKLKRLDEKLGILEKQPSPEEIREREREKEREREKELEKEQEQEREKEREKDRER 537

Query: 1556 TIDSEKDLLDDSD-------------DDDIEILEECIISAMPTKSSRKAKKPAQTASKLP 1602
              + EK+L  + +             + ++E  +E        K   K  +  +   KL 
Sbjct: 538  QQEKEKELEKEQEKQREMEKERKQEKEKELERQKEKEKELQKMKEQEKECELEKEREKLE 597

Query: 1603 PPV-ARKPSQLPVYKLLPSQNRLQPQKHVSFTPGD 1636
              +  R+P+  P+ +   S+N    ++   FT  D
Sbjct: 598  EKIEPREPNLEPMVEKQESENSCNKEEEPVFTRQD 632



 Score = 35.0 bits (79), Expect = 1.1
 Identities = 90/448 (20%), Positives = 170/448 (37%), Gaps = 81/448 (18%)

Query: 2244 SPVSKKGPPLKTPASKSPSEGQ-TATTSPRGAKPSVKSELSPVARQTSQIGGSSKAPSRS 2302
            S ++    P   PA+ SP+    TA T P  A P+    L+P +         + AP+  
Sbjct: 1866 SALASTSAPTPAPAASSPAAPVITAPTIPASA-PTASVPLAPASASAP-----APAPTPV 1919

Query: 2303 GSRDSTPSRPAQ------QPLSRPIQSPGRNSISPGRNGISPPNKLSQLPRTSSPSTAST 2356
             + +  P  PAQ      +P+  P+Q+  ++S  P      PP+   +LP   +P+    
Sbjct: 1920 SAPNPAPPAPAQTQAQTHKPVQNPLQTTSQSSKQP------PPS--IRLPSAQTPNGTDY 1971

Query: 2357 KSSGSGKMSYTSPGRQMSQ------------QNLTKQTGLSK---------------NAS 2389
             +SG    +  S G   ++             +++K+ G                  +  
Sbjct: 1972 VASGKSIQTPQSHGTLTAELWDNKVAPPAVLNDISKKLGPISPPQPPSVSAWNKPLTSFG 2031

Query: 2390 SIPRSESASKGLNQMNNGNGANKKVELSRMSSTKSSGSESDRSERPVLVRQSTFIKEAPS 2449
            S P SE A  G       +G     +  +  +  S+G+E++    PVL  +S    + P 
Sbjct: 2032 SAPSSEGAKNG-----QESGLEIGTDTIQFGAPASNGNENE--VVPVLSEKSA--DKIPE 2082

Query: 2450 PTLRRKLEESASFESLSPSSRP-ASPTRSQAQTP---VLSPSLPDMSLSTHSSVQAGGWR 2505
            P  +R+ +  A    +     P  SP  ++   P       SL +  +     V+  G  
Sbjct: 2083 PKEQRQKQPRAG--PIKAQKLPDLSPVENKEHKPGPIGKERSLKNRKVKDAQQVEPEGQE 2140

Query: 2506 KLPPNLSPTIEYNDGRPAKR-HDIARSHSESPSRLPINRS--GTWKRE----HSKHSSSL 2558
            K  P    T+   D    K    ++   +E  + + ++ +  GT  +E    ++  SSSL
Sbjct: 2141 KPSP---ATVRSTDPVTTKETKAVSEMSTEIGTMISVSSAEYGTNAKESVTDYTTPSSSL 2197

Query: 2559 PRVSTWRRTGSSSSILS--ASSESSEKAKSEDEKHVNSISGTKQSKENQVSAKGTWRKIK 2616
            P       T    ++++      +    K E  +  +S++    +  +      + RK  
Sbjct: 2198 PNTVATNNTKMEDTLVNNVPLPNTLPLPKRETIQQSSSLTSVPPTTFSLTFKMESARKAW 2257

Query: 2617 EN------EFSPTNSTSQTVSSGATNGA 2638
            EN      + SP  ST+  +++G ++ A
Sbjct: 2258 ENSPNVREKGSPVTSTAPPIATGVSSSA 2285



 Score = 32.0 bits (71), Expect = 8.9
 Identities = 61/339 (17%), Positives = 118/339 (34%), Gaps = 22/339 (6%)

Query: 1681 SGEFEKRDTIPTEGRSTDEAQGGKTSSVTIPELDDNKAEEGDILAECINSAMPKGKSHKP 1740
            S + E+    P E  S D  QG K S     E ++NK E  ++     +S +P   S   
Sbjct: 335  SDDDEQGSNSPKENNSED--QGSKAS-----ENNENKKETDEVSNTKSSSQIPAQPSVAK 387

Query: 1741 FRVKKIMDQVQQASASSSAPNKNQLDGKKKKPTS----PVKPIPQNTEYRT-------RV 1789
                K     Q+   SS  P   +L  ++  P      P +P P  ++ +        + 
Sbjct: 388  VPYGKGPSFNQERGTSSHLPPPPKLLAQQHPPPDRQAVPGRPGPFPSKQQVADEDEIWKQ 447

Query: 1790 RKNADSKNNLNAERVFSDNKDSKKQNLKNNSKVFNDKLPNNEDRVRGSFAFDSPHHYTPI 1849
            R+   S+ +   ER     ++ +++  +       +KL   ++++       SP      
Sbjct: 448  RRRQQSEISAAVERARKRREEEERRMEEQRKAACAEKLKRLDEKLGILEKQPSPEEIRER 507

Query: 1850 EGTPYCFSRNDSLSSLDFDDDDVDLSREKAELRKAKENKESEAKVTSHTELTSNQ-QSAN 1908
            E       R          + + +  REK   R+ ++ KE E +     E+   + Q   
Sbjct: 508  EREK---EREREKELEKEQEQEREKEREKDRERQQEKEKELEKEQEKQREMEKERKQEKE 564

Query: 1909 KTQAIAKQPINRGQPKPILQKQSTFPQSSKDIPDRGAATDEKLQNFAIENTPVCFSHNSS 1968
            K     K+     Q     +K+    +  + + ++    +  L+    +       +   
Sbjct: 565  KELERQKEKEKELQKMKEQEKECELEKEREKLEEKIEPREPNLEPMVEKQESENSCNKEE 624

Query: 1969 LSSLSDIDQENNNKENEPIKETEPPDSQGEPSKPQASGY 2007
                +  D   + KE  P+     P+S  +P     SGY
Sbjct: 625  EPVFTRQDSNRSEKEATPVVHETEPESGSQPRPAVLSGY 663


>gi|89026265 PREDICTED: mucin 12 [Homo sapiens]
          Length = 978

 Score = 62.0 bits (149), Expect = 8e-09
 Identities = 140/659 (21%), Positives = 234/659 (35%), Gaps = 76/659 (11%)

Query: 2221 MPSISRGRT-MIHIPGVRNSSSSTSPVSKKGPPL-KTPASKSPSEGQTATTSPRGAKPSV 2278
            M  IS G T    +PG    S++T+ +S+K      +P S   +    +TTS   ++ S 
Sbjct: 1    MSPISSGSTETTALPG----STTTAGLSEKSTTFYSSPRSPDTTLSPASTTSSGVSEEST 56

Query: 2279 KSELSPVARQTSQIGGSSKAPSRSGSRDSTPSRPAQQPLSRPIQSPGRNSISPGRNGI-- 2336
             S   P +  T+   GS+  P  S    ++ S P     +    S   +S+ P       
Sbjct: 57   TSHSRPGSTHTTAFPGSTTMPGVSQESTASHSSPGSTDTTLSPGSTTASSLGPESTTFHS 116

Query: 2337 SPPNKLSQLPRTSSPSTASTKSSGSGKMSYTSPGRQMSQQNLTKQTGLSKNASSIPRSE- 2395
             P +  + L   ++ ++   ++S     S  SP   +S    T + G S    S P S+ 
Sbjct: 117  GPGSTETTLLPDNTTASGLLEASTPVHSSTGSPHTTLSPAGSTTRQGESTTFQSWPNSKD 176

Query: 2396 ---------SASKGLNQMNNGNGANKKVELSRMSSTKSSGSESD---------------- 2430
                     SA   L+  ++G+ ++        SST    SE                  
Sbjct: 177  TTPAPPTTTSAFVELSTTSHGSPSSTPTTHFSASSTTLGRSEESTTVHSSPVATATTPSP 236

Query: 2431 -RSERPVLVRQSTFIKEAPSPTLRRKLEESASFESLSPSSRP--ASPTRSQAQTPVLSPS 2487
             RS    LV +ST    +P  T      ES++    S  SR   +S T + +  P  + +
Sbjct: 237  ARSTTSGLVEESTAYHSSPGSTQTMHFPESSTASGRSEESRTSHSSTTHTISSPPSTTSA 296

Query: 2488 LPDMSLSTHSSVQAGGWRKLPPNLSPTIEYNDGRPAKRHDIARSHSESPSRLPINRSG-- 2545
            L +   S HSS  +      P   S T           H    ++  +P       SG  
Sbjct: 297  LVEEPTSYHSSPGSIATTHFPE--SSTTSGRSEESTASHSSPDTNGITPLPAHFTTSGRI 354

Query: 2546 ----TWKREHSKHSSSLPRVSTWRRTGSSSSILSASSESSEKAKSEDEKHVNSISGTKQS 2601
                T+        ++L   +T     + S+IL +SS S ++  S      +SISG   S
Sbjct: 355  AESTTFYISPGSMETTLASTTTTPGLSAKSTILYSSSRSPDQTLSPASMTSSSISGEPTS 414

Query: 2602 KENQVSAKGTWRKIKENEFSPTNSTSQTVSSGATNGAESKTLIYQMAPAVSKTEDVWVRI 2661
              +Q  +  T        F  + +TS       T  ++  +    ++P  S T   + + 
Sbjct: 415  LYSQAESTHT------TAFPASTTTSGLSQESTTFHSKPGSTETTLSPG-SITTSSFAQE 467

Query: 2662 EDCPINNPRSGRSPTGNTPPVIDSVSEKANPNIKDSKDNQAKQNVGNGSVPMRTVGLENR 2721
               P + P S  S        +  +SE++                  GS         N 
Sbjct: 468  FTTPHSQPGSALSTVSPASTTVPGLSEESTTFYSSP-----------GSTETTAFSHSNT 516

Query: 2722 LNSFIQVDAPDQKGTEIKPGQNNPV-PVSETNESSIVERTPFSSSSSSKHSSP------S 2774
            ++   Q   P        PG  + V P + T      E T F SSS +  ++P      +
Sbjct: 517  MSIHSQQSTPFPD----SPGFTHTVLPATLTTTDIGQESTAFHSSSDATGTTPLPARSTA 572

Query: 2775 GTVAARVTPFNYNPSPRKSSADSTSARPSQI--PTPVNNNTKKRDSKTDSTESSGTQSP 2831
              +    T F  +PSP  ++    S+  S +   +   + +    S   STES  T +P
Sbjct: 573  SDLVGEPTTFYISPSPTYTTLFPASSSTSGLTEESTTFHTSPSFTSTIVSTESLETLAP 631



 Score = 33.5 bits (75), Expect = 3.1
 Identities = 60/276 (21%), Positives = 105/276 (38%), Gaps = 36/276 (13%)

Query: 1177 IDYSLKYATDIPSSQKQSFSFSKSSSGQS--SKTEHMSSSSENTSTPSSNAKRQNQLHPS 1234
            ++ S  Y +   S+Q   F  S ++SG+S  S+T H S++   +S PS+ +    +  P+
Sbjct: 245  VEESTAYHSSPGSTQTMHFPESSTASGRSEESRTSHSSTTHTISSPPSTTSALVEE--PT 302

Query: 1235 SAQSRSGQ------PQKAAT---CKVSSINQETIQTYCVEDTPICFSRCSSLS------- 1278
            S  S  G       P+ + T    + S+ +  +  T  +   P  F+    ++       
Sbjct: 303  SYHSSPGSIATTHFPESSTTSGRSEESTASHSSPDTNGITPLPAHFTTSGRIAESTTFYI 362

Query: 1279 SLSSAEDEIGCNQTTQEADSANTLQIAEIKEKIGTRSAEDPVSEVPAVSQHPRTKSSRLQ 1338
            S  S E  +    TT    + +T+  +       +RS +  +S     S     + + L 
Sbjct: 363  SPGSMETTLASTTTTPGLSAKSTILYS------SSRSPDQTLSPASMTSSSISGEPTSLY 416

Query: 1339 GSSLSSESARHKAVEFSSGAKSPSKSGAQTPKSPPEHYVQETPLMFSRCTSVSSLDSF-- 1396
              + S+ +    A   +SG    S +    P S       ET L     T+ S    F  
Sbjct: 417  SQAESTHTTAFPASTTTSGLSQESTTFHSKPGS------TETTLSPGSITTSSFAQEFTT 470

Query: 1397 -ESRSIASSVQSEPCSGMVSGIISPS-DLPDSPGQT 1430
              S+  ++     P S  V G+   S     SPG T
Sbjct: 471  PHSQPGSALSTVSPASTTVPGLSEESTTFYSSPGST 506


>gi|238624188 diffuse panbronchiolitis critical region 1 protein [Homo
            sapiens]
          Length = 1393

 Score = 61.6 bits (148), Expect = 1e-08
 Identities = 248/1342 (18%), Positives = 463/1342 (34%), Gaps = 227/1342 (16%)

Query: 1202 SGQSSKTEHMSSSSENTSTPSSNAKRQNQ-LHPSSAQSRSGQPQKAATCKVSSINQETIQ 1260
            +G S   +H SS+  + + P+S     NQ   P     RS  P  + T    S  ++ I 
Sbjct: 100  TGNSKTIDHKSSTDNHEAPPTSEENSSNQGKDPMIRNQRSVDPADSTTTHKESAGKKHI- 158

Query: 1261 TYCVEDTPICFSRCSSLSSLSSAEDEIGCNQTTQEADSANTLQIAEIKEKIGTRSAEDPV 1320
                  TP             + + +I C ++T    +     +    +K G R  E  +
Sbjct: 159  ------TP-------------APKSKINCRKSTTGKST-----VTRKSDKTG-RPLEKSM 193

Query: 1321 S--EVPAVSQHPRTKSSRLQGSSLSSESARHKAVEFSSGAKSPSKSGAQTPKSPPEHYVQ 1378
            S  +  + S H  T S    G+S      + K+  F     + SK+  +T  +P E    
Sbjct: 194  STLDKTSTSSHKTTTSFHNSGNS----QTKQKSTSFPEKITAASKTTYKTTGTPEESEKT 249

Query: 1379 ETPLMFSRCTSVSSLDSFESRSIASSVQSEPCSGMVSGIISPSDLPDSPGQTMPPSRSKT 1438
            E     SR T  S  D   +++  +  ++   + +   +  P+   +  G+T   + + T
Sbjct: 250  ED----SRTTVAS--DKLLTKTTKNIQETISANELTQSLAEPT---EHGGRT--ANENNT 298

Query: 1439 PPPPPQTAQTKREVPKNKA-PTAEKRESGPKQAAVNAA------VQRVQVLPDADTLLHF 1491
            P P   T   +R   +N     AE  E+  + A  N A       +  ++  + +T L F
Sbjct: 299  PSPAEPTENRERTANENTTLSPAEPIENRERTANENTAPFPAGPTENREMTANENTTL-F 357

Query: 1492 ATESTPDGFSCSSSLSALSLDEPFIQKDVELRIMPPVQENDNGNETES-EQPKESNENQE 1550
              E T  G   ++  +  S  EP              +   N N T S  +P E  E   
Sbjct: 358  PAEPTEHGERTANENTTPSPAEP----------TEHGERTANENTTPSPAEPTEHGERTP 407

Query: 1551 KEAEKTIDSEKDLLDDSDDDDIEILEECIISAMPTKSSRKAKKPAQTASKLPPPVARKPS 1610
               +KT  S  +  +  +   +         A PT++  +      T S   P   R+ +
Sbjct: 408  FANDKTTSSSAESTEHGERTPLANENTTPSPAEPTENRERTANENTTPSPAGPTENRETT 467

Query: 1611 ---QLPVYKLLPSQNRLQPQKHVSFTPGDDMPRVYCVEGTPINFSTATSLSDLTIESPPN 1667
               +  +  + P++NR +   +   TP    P          N  T +S ++ T      
Sbjct: 468  ANEKTTLSPVEPTENR-ETTANEKTTPSPAEPTENGQRTPFANEKTTSSSAEPTEHGERT 526

Query: 1668 ELAAGEGVRGGAQSGEFEKRDTIPTEGRSTDEAQGGKTSSVTIPELDDNKAEEGDILAEC 1727
             LA        A+          PTE R     +    S     E  D      +     
Sbjct: 527  PLANENTTPSPAE----------PTENRERTANEKTTPSPAEPTENGDRTPLANEKTTPS 576

Query: 1728 INSAMPKGKSHKPFRVKKIMDQVQQASASSSAPNKNQLDGKKKKPTSPVKPIPQNTEYRT 1787
            +      G+   PF  +K        ++SS+ P +++    ++ P +     P   E   
Sbjct: 577  LAEPTENGQ-RTPFANEK-------TTSSSAEPTEHE----ERTPLANENTTPSPAE--- 621

Query: 1788 RVRKNADSKNNLNAERVFSDNKDSKKQNLKNNSKVFNDKLPNNEDRVRGSFAFDSPHHYT 1847
               +N +   N N     +   ++++      + +F  +   N +R        SP   T
Sbjct: 622  -PTENRERTANENTTPSPAGPTENREMTANEKTTLFPAEPTENRERTANEKTTSSPAEPT 680

Query: 1848 PI-EGTPYCFSRNDSLSSLDFDDDD-VDLSREKAELRKAKENKESEAKVTSHTELTSNQQ 1905
               + TP+   +  S S+   +  +   L+ E   L        S A+ T + E T+N+ 
Sbjct: 681  ENGQRTPFANEKTTSSSAEPTEHGERTPLANENTTL--------SPAEPTENRERTANE- 731

Query: 1906 SANKTQAIAKQPINRGQPKPILQKQSTFPQSSKDIPDRGAATDEKLQNFAIENTPVCFSH 1965
               KT     +P    + +   +  +  P    +  DR    +EK        TP     
Sbjct: 732  ---KTTPFPAEP-TENRERTANENTTPSPAQPTENGDRTPLANEK-------TTP----- 775

Query: 1966 NSSLSSLSDIDQENNNKENEPIKETEPPDSQGEPSKPQASGYAPKSFHVEDTPVCFSRNS 2025
                     + +   N +  P    +   S  EP++           H E TP+     +
Sbjct: 776  --------SLAEPTENGKRTPFANEKTTSSSAEPTE-----------HAERTPLANENTT 816

Query: 2026 SLSSLSIDSEDDLLQECISSAMPKKKKPSRLKGDNEKHSPRNMGGILGEDLTLDLKDIQR 2085
            S  +   ++ +    E  ++  P +   +R    NEK +P                    
Sbjct: 817  SSPAEPTENRERTANE-KTTQFPAEPTENRESTANEKTTPFP------------------ 857

Query: 2086 PDSEHGLSPDSENFDWKAIQEGANSIVSSLHQAAAAACLSRQASSDSDSILSLKSGISLG 2145
                   +  +EN +W A +                  LS    ++ + +  L +  +  
Sbjct: 858  -------AEPTENREWTANEN---------------TTLSPAEPTEHEEMTPLANEKTTL 895

Query: 2146 SPFHLTPDQEEKPFTSNK-GPRILKP---GEKSTLETK-KIESESKGIKGGKKVYKSLIT 2200
            SP   T + E  PFT+ K  P   +P   GE++ L  +    S ++  + G+++     T
Sbjct: 896  SPAEPTENGERTPFTNEKTTPSSAEPTEHGERTPLANEITTPSRAEPTEHGERIANEKAT 955

Query: 2201 ---GKVRSNSEISGQMKQPLQANMPSISRGRTMIHIPGVRNSSSSTSPV------SKKGP 2251
                K   + E +        +  P+ +  RT +      N +++TSP        +   
Sbjct: 956  PSPAKPTEHGETTVNEDTTPSSAEPTENGERTPL-----ANENTTTSPTESTEHGERTAN 1010

Query: 2252 PLKTPASKSPSEGQTAT------TSPRGAKPSVKSELSPVARQTSQIGGSSKAPSRSGSR 2305
               TP+   P+E    T      T P  AKP+   E++P A + +    S   P+  G +
Sbjct: 1011 EKTTPSPAEPTEHGERTPSANEKTIPSPAKPTEHEEMTPSANENTT--PSPVKPTEHGEK 1068

Query: 2306 DSTPSRPAQQPLSRPIQSPGRNSISPGRNGISPPNKLSQLPRTSSPSTASTKSSGSGKMS 2365
             +  +         P +   + + +  +   S         RT+SP+   T S+     S
Sbjct: 1069 TTLANEKITLSPEGPTEHGAKTTSANEKITPSLAKPTEHGERTTSPNDKITSSAAE---S 1125

Query: 2366 YTSPGRQMSQQNLTKQTGLSKNASSIPRSESASKGLNQMNNGNGANKKVELSRMSSTKSS 2425
                 R  S   +T     ++      R+  A + + Q+   +  + +       +T ++
Sbjct: 1126 TEHRDRATSANVITPAP--AEPIKHAKRTTLAHEKMTQVTEKSTEHPE------KTTSTT 1177

Query: 2426 GSESDRSERPVLVRQSTFIKEAPSPTLRRKLEESASFESL------SPSSRPASPTRSQA 2479
               +   E+P L  + T   +  +  +  K  E+    +L      +P     +P ++ A
Sbjct: 1178 EKTTRTPEKPTLYSEKTICTKGKNTPVPEKPTENLGNTTLTTETIKAPVKSTENPEKTAA 1237

Query: 2480 QTPVLSPSLP---DMSLSTHSS 2498
             T  + PS+    D SL+T SS
Sbjct: 1238 VTKTIKPSVKVTGDKSLTTTSS 1259



 Score = 51.6 bits (122), Expect = 1e-05
 Identities = 111/598 (18%), Positives = 201/598 (33%), Gaps = 84/598 (14%)

Query: 2255 TPASKSPSEGQTATTSPRGAKPSVKSELSPVARQTSQIGGSSKAPSRSGSRDSTPSRPAQ 2314
            TP+   P+E +  T + +     V+   +       +   S   P+ +G R    +    
Sbjct: 454  TPSPAGPTENRETTANEKTTLSPVEPTENRETTANEKTTPSPAEPTENGQRTPFANEKTT 513

Query: 2315 QPLSRPIQSPGRNSISPGRNGISPPNKLSQLPRTSSPSTASTKSSGSGKMSYTSPGRQMS 2374
               + P +   R  ++      SP        RT++  T  + +  +     T    + +
Sbjct: 514  SSSAEPTEHGERTPLANENTTPSPAEPTENRERTANEKTTPSPAEPTENGDRTPLANEKT 573

Query: 2375 QQNLTKQTGLSKNASSIPRSESASKGLNQMNNGNGANKKVELSRMSSTKSSGSESDRSER 2434
              +L + T   +N    P                 AN+K       +T SS   ++  ER
Sbjct: 574  TPSLAEPT---ENGQRTP----------------FANEK-------TTSSSAEPTEHEER 607

Query: 2435 PVLVRQSTFIKEAPSPTLRRKLEESASFESLSPSSRPASPTRSQAQT----PVLSPSLPD 2490
              L  ++T     PSP    +  E  + E+ +PS  PA PT ++  T      L P+ P 
Sbjct: 608  TPLANENT----TPSPAEPTENRERTANENTTPS--PAGPTENREMTANEKTTLFPAEP- 660

Query: 2491 MSLSTHSSVQAGGWRKLPPNLSPTIEYNDGRPAKRHDIARSHSESPSRLPINRSGTWKRE 2550
                T +  +    +       PT         +R   A   + S S  P          
Sbjct: 661  ----TENRERTANEKTTSSPAEPT------ENGQRTPFANEKTTSSSAEP---------- 700

Query: 2551 HSKHSSSLPRVSTWRRTGSSSSILSASSESSEKAKSEDEKHVNSISGTKQSKENQVSAKG 2610
             ++H    P         + ++ LS +  +  + ++ +EK     +   +++E   +   
Sbjct: 701  -TEHGERTP-------LANENTTLSPAEPTENRERTANEKTTPFPAEPTENRERTANENT 752

Query: 2611 TWRKIK--ENEFSPTNSTSQTVSSGATNGAESKTLIYQMAPAVSKTEDVWVRIEDCPINN 2668
            T    +  EN      +  +T  S A      K   +      S + +     E  P+ N
Sbjct: 753  TPSPAQPTENGDRTPLANEKTTPSLAEPTENGKRTPFANEKTTSSSAEPTEHAERTPLAN 812

Query: 2669 PRSGRSPTGNTPPVIDSVSEKANPNIKDSKDNQAKQNVGNGSVPMRTVGLENR-----LN 2723
              +  SP   T     + +EK      +  +N+ +      + P      ENR      N
Sbjct: 813  ENTTSSPAEPTENRERTANEKTTQFPAEPTENR-ESTANEKTTPFPAEPTENREWTANEN 871

Query: 2724 SFIQVDAPDQKGTEIKPGQNNPVPVSETNESSIVERTPF-------SSSSSSKHSSPSGT 2776
            + +    P +   E+ P  N    +S    +   ERTPF       SS+  ++H   +  
Sbjct: 872  TTLSPAEPTEH-EEMTPLANEKTTLSPAEPTENGERTPFTNEKTTPSSAEPTEHGERTPL 930

Query: 2777 VAARVTPFNYNPSPRKSSADSTSARPSQI-PTPVNNNTKKRDSKTDSTE--SSGTQSP 2831
                 TP    P+       +  A PS   PT     T   D+   S E   +G ++P
Sbjct: 931  ANEITTPSRAEPTEHGERIANEKATPSPAKPTEHGETTVNEDTTPSSAEPTENGERTP 988



 Score = 43.1 bits (100), Expect = 0.004
 Identities = 192/1081 (17%), Positives = 371/1081 (34%), Gaps = 133/1081 (12%)

Query: 977  GQMKPSIESYSEDDESK-FCSYGQY------PADLAHKIHSANHMDDNDGELDTPINYSL 1029
            GQ  P +   +E  E K  C+  ++      P   +  I   +  D+++    +  N S 
Sbjct: 68   GQRPPELPKSTEIHEQKRHCNTTRHSKPTDKPTGNSKTIDHKSSTDNHEAPPTSEENSSN 127

Query: 1030 KYSDEQLNSGRQ-----SPSQNERWARPKHIIEDEIKQSEQRQSRNQSTTYPVYTESTDD 1084
            +  D  + + R      S + ++  A  KHI      +   R+S    +T    ++ T  
Sbjct: 128  QGKDPMIRNQRSVDPADSTTTHKESAGKKHITPAPKSKINCRKSTTGKSTVTRKSDKTGR 187

Query: 1085 KHLKFQPHFGQQECVSPYRSRGANGSETNRVGSNHGINQNVSQSLCQEDDYEDDKPTNYS 1144
                       ++ +S       +  +T     N G +Q   +S    +       T Y 
Sbjct: 188  P---------LEKSMSTLDKTSTSSHKTTTSFHNSGNSQTKQKSTSFPEKITAASKTTYK 238

Query: 1145 ERYSEEEQHEEEERPTNYSIKYNEEKRHVDQPIDYSLKYATDIPSSQKQSFSFSKSSSGQ 1204
               + EE  + E+  T  +                S K  T    + +++ S ++ +   
Sbjct: 239  TTGTPEESEKTEDSRTTVA----------------SDKLLTKTTKNIQETISANELTQSL 282

Query: 1205 SSKTEHMSSSSENTSTPSSNAKRQNQLHPSSAQSRSGQPQKAATCKVSSINQETIQTYCV 1264
            +  TEH   ++   +TPS     +N+   ++ ++ +  P +    +  + N+ T   +  
Sbjct: 283  AEPTEHGGRTANENNTPSPAEPTENR-ERTANENTTLSPAEPIENRERTANENT-APFPA 340

Query: 1265 EDTPICFSRCSSLSSLSSAEDEIGCNQTTQEADSANTLQIAEIKEKIGTRSAEDPVSEVP 1324
              T       +  ++L  AE      +T  E    NT        + G R+A +  +  P
Sbjct: 341  GPTENREMTANENTTLFPAEPTEHGERTANE----NTTPSPAEPTEHGERTANENTTPSP 396

Query: 1325 A--VSQHPRTKSSRLQGSSLSSESARH--------------KAVEFSSGAKSPSKSGAQT 1368
            A       RT  +  + +S S+ES  H               A    +  ++ +++   +
Sbjct: 397  AEPTEHGERTPFANDKTTSSSAESTEHGERTPLANENTTPSPAEPTENRERTANENTTPS 456

Query: 1369 PKSPPEHYVQETPLMFSRCTSVSSLDSFESRSIASSVQSEPCSGMVSGIISPSDLPDSPG 1428
            P  P E+  +ET    +  T++S ++  E+R   ++ ++ P         SP++ P   G
Sbjct: 457  PAGPTEN--RETTA--NEKTTLSPVEPTENRETTANEKTTP---------SPAE-PTENG 502

Query: 1429 QTMPPSRSKTPPPPPQTAQTKREVP---KNKAPT-AEKRESGPKQAAVNAAVQRVQVLPD 1484
            Q  P +  KT     +  +     P   +N  P+ AE  E+  + A         +   +
Sbjct: 503  QRTPFANEKTTSSSAEPTEHGERTPLANENTTPSPAEPTENRERTANEKTTPSPAEPTEN 562

Query: 1485 ADTLLHFATESTPDGFSCSSSLSALSLDEPFIQKDVELRIMPPVQENDN---GNETESEQ 1541
             D       ++TP      +  +      PF  +        P +  +     NE  +  
Sbjct: 563  GDRTPLANEKTTPS----LAEPTENGQRTPFANEKTTSSSAEPTEHEERTPLANENTTPS 618

Query: 1542 PKESNENQEKEA-EKTIDSEKDLLDDSDDDDIEILEECIISAMPTKSSRKAKKPAQTASK 1600
            P E  EN+E+ A E T  S     ++ +    E  +  +  A PT++  +      T+S 
Sbjct: 619  PAEPTENRERTANENTTPSPAGPTENREMTANE--KTTLFPAEPTENRERTANEKTTSSP 676

Query: 1601 LPPPVARKPSQLPVYKLLPSQNRLQPQKHVSFTPGDDMPRVYCVEGTPINFSTATSLSDL 1660
              P       + P      + +  +P +H   TP          E T ++ +  T   + 
Sbjct: 677  AEP--TENGQRTPFANEKTTSSSAEPTEHGERTP-------LANENTTLSPAEPTENRER 727

Query: 1661 TIESPPNELAAGEGVRGGAQSGEFEKRDTIPTEGRSTDEAQGGKT---SSVTIPELDDNK 1717
            T         A         + E    +T P+  + T+   G +T   +  T P L +  
Sbjct: 728  TANEKTTPFPAEPTENRERTANE----NTTPSPAQPTE--NGDRTPLANEKTTPSLAE-- 779

Query: 1718 AEEGDILAECINSAMPKGKSHKPFRVKKIMDQVQQASASSSAPNKNQLDGKKKKPTS-PV 1776
              E        N       +      ++     +  ++S + P +N+     +K T  P 
Sbjct: 780  PTENGKRTPFANEKTTSSSAEPTEHAERTPLANENTTSSPAEPTENRERTANEKTTQFPA 839

Query: 1777 KPI--------PQNTEYRTRVRKNADSKNNLNAERVFSDNKDSKKQNLKNNSKVFNDKLP 1828
            +P          + T +     +N +   N N     ++  + ++     N K       
Sbjct: 840  EPTENRESTANEKTTPFPAEPTENREWTANENTTLSPAEPTEHEEMTPLANEKTTLSPAE 899

Query: 1829 NNEDRVRGSFAFDSPHHYTPIEGTPYCFSRNDSLSSLDFDDDDVDLSREKAELRKAKENK 1888
              E+  R  F  +     TP    P        L++ +          E  E    ++  
Sbjct: 900  PTENGERTPFTNEKT---TPSSAEPTEHGERTPLAN-EITTPSRAEPTEHGERIANEKAT 955

Query: 1889 ESEAKVTSHTELTSNQQSANKTQAIAKQPINRGQPKPIL-QKQSTFPQSSKDIPDRGAAT 1947
             S AK T H E T N+     T   + +P   G+  P+  +  +T P  S +  +R A  
Sbjct: 956  PSPAKPTEHGETTVNED----TTPSSAEPTENGERTPLANENTTTSPTESTEHGERTA-- 1009

Query: 1948 DEKLQNFAIENTPVCFSHNSSLSSLSD--IDQENNNKENEPIKETEPPDSQGEPSKPQAS 2005
            +EK      E T     H     S ++  I       E+E +  +   ++   P KP   
Sbjct: 1010 NEKTTPSPAEPT----EHGERTPSANEKTIPSPAKPTEHEEMTPSANENTTPSPVKPTEH 1065

Query: 2006 G 2006
            G
Sbjct: 1066 G 1066



 Score = 37.7 bits (86), Expect = 0.16
 Identities = 65/329 (19%), Positives = 122/329 (37%), Gaps = 37/329 (11%)

Query: 2522 PAKRHDIARSHSESPSRLPINRSGTWKREHSKHSSSLPRVSTWRRTGSSSSILSASSESS 2581
            PA +  I    S +       +S    R   K  S+L + ST     ++S   S +S++ 
Sbjct: 160  PAPKSKINCRKSTTGKSTVTRKSDKTGRPLEKSMSTLDKTSTSSHKTTTSFHNSGNSQTK 219

Query: 2582 EKAKSEDEKHVNSISGTKQSKENQVSAKGTWRKIKENEFSPTNSTSQTVSSGATNGAESK 2641
            +K+ S  EK   +   T ++        GT  + ++ E S T   S  + +  T   +  
Sbjct: 220  QKSTSFPEKITAASKTTYKTT-------GTPEESEKTEDSRTTVASDKLLTKTTKNIQET 272

Query: 2642 TLIYQMAPAVSKTEDVWVRIEDCPINNPRSGRSPTGNTPPVIDSVSEKANPNIKDSKDNQ 2701
                ++  ++++  +   R  +   NN  S   PT N     +  +  +     ++++  
Sbjct: 273  ISANELTQSLAEPTEHGGRTAN--ENNTPSPAEPTENRERTANENTTLSPAEPIENRERT 330

Query: 2702 AKQNVGNGSVPMRTVGLENRL-----NSFIQVDAPDQKGTEIKPGQNNPVPVSET----- 2751
            A +N    + P      ENR      N+ +    P + G         P P   T     
Sbjct: 331  ANEN----TAPFPAGPTENREMTANENTTLFPAEPTEHGERTANENTTPSPAEPTEHGER 386

Query: 2752 --NESSIV---------ERTPFSSSSSSKHSSPSGTVAARVTPFNYN--PSPRKSSAD-S 2797
              NE++           ERTPF++  ++  S+ S     R    N N  PSP + + +  
Sbjct: 387  TANENTTPSPAEPTEHGERTPFANDKTTSSSAESTEHGERTPLANENTTPSPAEPTENRE 446

Query: 2798 TSARPSQIPTPVNNNTKKRDSKTDSTESS 2826
             +A  +  P+P      +  +  + T  S
Sbjct: 447  RTANENTTPSPAGPTENRETTANEKTTLS 475


>gi|239754668 PREDICTED: mucin 12 [Homo sapiens]
          Length = 1952

 Score = 60.8 bits (146), Expect = 2e-08
 Identities = 139/656 (21%), Positives = 234/656 (35%), Gaps = 76/656 (11%)

Query: 2224 ISRGRT-MIHIPGVRNSSSSTSPVSKKGPPL-KTPASKSPSEGQTATTSPRGAKPSVKSE 2281
            IS G T    +PG    S++T+ +S+K      +P S   +    +TTS   ++ S  S 
Sbjct: 975  ISSGSTETTALPG----STTTAGLSEKSTTFYSSPRSPDTTLSPASTTSSGVSEESTTSH 1030

Query: 2282 LSPVARQTSQIGGSSKAPSRSGSRDSTPSRPAQQPLSRPIQSPGRNSISPGRNGI--SPP 2339
              P +  T+   GS+  P  S    ++ S P     +   +S   +S+ P        P 
Sbjct: 1031 SRPGSTHTTAFPGSTTMPGVSQESTASHSSPGSTDTTLSPRSTTASSLGPESTTFHSGPG 1090

Query: 2340 NKLSQLPRTSSPSTASTKSSGSGKMSYTSPGRQMSQQNLTKQTGLSKNASSIPRSE---- 2395
            +  + L   ++ ++   ++S     S  SP   +S    T + G S    S P S+    
Sbjct: 1091 STETTLLPDNTTASGLLEASTPVHSSTGSPRTTLSPAGSTTRQGESTTFQSWPSSKDTMP 1150

Query: 2396 ------SASKGLNQMNNGNGANKKVELSRMSSTKSSGSESD-----------------RS 2432
                  SA   L+  ++G+ ++        SST    SE                   RS
Sbjct: 1151 APPTTTSAFVELSTTSHGSPSSIPTTHFSASSTTFGRSEESTTVHSSPVAPATTPSPARS 1210

Query: 2433 ERPVLVRQSTFIKEAPSPTLRRKLEESASFESLSPSSRP--ASPTRSQAQTPVLSPSLPD 2490
                LV +ST    +P  T      ES++    S  SR   +S T + +  P  + +L +
Sbjct: 1211 TTSGLVEESTAYHSSPGSTQTMHFPESSTASGRSEESRTSHSSTTHTISSPPSTTSALVE 1270

Query: 2491 MSLSTHSSVQAGGWRKLPPNLSPTIEYNDGRPAKRHDIARSHSESPSRLPINRSG----- 2545
               S HSS  +      P   S T           H    ++  +P       SG     
Sbjct: 1271 EPTSYHSSPGSIATTHFPE--SSTTSGRSEESTASHSSPDTNGITPLPAHFTTSGRIAES 1328

Query: 2546 -TWKREHSKHSSSLPRVSTWRRTGSSSSILSASSESSEKAKSEDEKHVNSISGTKQSKEN 2604
             T+        ++L   +T     + S+IL +SS S ++  S      +SISG   S  +
Sbjct: 1329 TTFYISPGSMETTLASTATTPGLSAKSTILYSSSRSPDQTLSPASMTSSSISGEPTSLYS 1388

Query: 2605 QVSAKGTWRKIKENEFSPTNSTSQTVSSGATNGAESKTLIYQMAPAVSKTEDVWVRIEDC 2664
            Q  +  T        F  + +TS       T  ++  +    ++P  S T   + +    
Sbjct: 1389 QAESTHT------TAFPASTTTSGLSQESTTFHSKPGSTETTLSPG-SITTSSFAQEFTT 1441

Query: 2665 PINNPRSGRSPTGNTPPVIDSVSEKANPNIKDSKDNQAKQNVGNGSVPMRTVGLENRLNS 2724
            P + P S  S        +  +SE++                  GS         N ++ 
Sbjct: 1442 PHSQPGSALSTVSPASTTVPGLSEESTTFYSSP-----------GSTETTAFSHSNTMSI 1490

Query: 2725 FIQVDAPDQKGTEIKPGQNNPV-PVSETNESSIVERTPFSSSSSSKHSSP------SGTV 2777
              Q   P        PG  + V P + T      E T F SSS +  ++P      +  +
Sbjct: 1491 HSQQSTPFPD----SPGFTHTVLPATLTTTDIGQESTAFHSSSDATGTTPLPARSTASDL 1546

Query: 2778 AARVTPFNYNPSPRKSSADSTSARPSQI--PTPVNNNTKKRDSKTDSTESSGTQSP 2831
                T F  +PSP  ++    S+  S +   +   + +    S   STES  T +P
Sbjct: 1547 VGEPTTFYISPSPTYTTLFPASSSTSGLTEESTTFHTSPSFTSTIVSTESLETLAP 1602



 Score = 50.1 bits (118), Expect = 3e-05
 Identities = 126/620 (20%), Positives = 211/620 (34%), Gaps = 65/620 (10%)

Query: 2223 SISRGRTMIHIPGVRNSSS-STSPVSKKGPPLKTPASKSPSEGQTATTSPRGAKPSVKSE 2281
            S  R     H+P    SS  S    +    P  T  +  P     +TT P  ++ S  S 
Sbjct: 562  SSPRSPDTTHLPASMTSSGVSEESTTSHSRPGSTHTTAFPG----STTMPGLSQESTASH 617

Query: 2282 LSPVARQTSQIGGSSKAPSRSGSRDSTPSRPAQQPLSRPIQSPGRNSISPGRNGISPPNK 2341
             SP    T+   GS+ A S      +  SRP     +     P   + S       P + 
Sbjct: 618  SSPGPTDTTLSPGSTTASSLGPEYTTFHSRPGS---TETTLLPDNTTASGLLEASMPVHS 674

Query: 2342 LSQLPRTSSPSTASTKSSGSGKMSYTSPGRQ--------MSQQNLTKQTGLSKNASSIP- 2392
             ++ P T+     ST   G     ++ P            +   +   T    + SSIP 
Sbjct: 675  STRSPHTTLSPAGSTTRQGESTTFHSWPSSNDTRPAPPTTTSAFVEPSTTSHGSPSSIPT 734

Query: 2393 ---RSESASKGL----NQMNNGNGANKKVELSRMSSTKSSGSESDRSERPVLVRQSTFIK 2445
                + S + GL       ++  G+ + +      +T   G ES  S        +  I 
Sbjct: 735  THISARSTTSGLVEESTTYHSSPGSTQTMHFPESDTTSGRGEESTTSHSST----THTIS 790

Query: 2446 EAPSPTLRRKLEESASFESLSPSSRPASPTRSQAQTPVLSPSLPDMSLSTHSSVQAGGWR 2505
             APS T    +EE  S+ S SP S   +     + T   S    + S+++HSS  A G  
Sbjct: 791  SAPS-TTSALVEEPTSYHS-SPGSTATTHFPDSSTTSGRS----EESIASHSSQDATGTI 844

Query: 2506 KLPPNLSPTIEYNDGRPAKRHDIARSHSESPSRLP--INRSGTWKREHSKHSSSLPRVST 2563
             LP   + ++   +   +       S S   + LP      G  +R  + HSS     +T
Sbjct: 845  VLPARSTNSVLLGESTTSP----ISSGSMETTALPGSTTTPGLSERSTTFHSSPRSPATT 900

Query: 2564 WRRTGSSSSILSASSESSEKAKSEDEKHVNSISGTKQSKENQVSAKGTWRKIKENEFSPT 2623
                 ++SS +S  S +S              S T        +   +     +    P 
Sbjct: 901  LSPASTTSSGVSEESTTSHSRPGSTHTTAFPDSTTTPGLSRHSTTSHSSPGSTDTTLLPA 960

Query: 2624 NSTSQTVSSGATNGAESKTLIYQMAPAVSKTEDVWVRIEDCPINNPRSGRSPTGNTPPVI 2683
            ++T+  V    T+   S +      P  + T  +  +      ++PRS  +         
Sbjct: 961  STTTXLVGEPTTSPISSGSTETTALPGSTTTAGLSEK-STTFYSSPRSPDTTLSPASTTS 1019

Query: 2684 DSVSEKANPNIKDSKDNQAKQNVGNGSVPMRTVGLENRLNSFIQVDAPDQKGTEIKPGQN 2743
              VSE++  +   S+          GS  M  V  E+  +      +P    T + P   
Sbjct: 1020 SGVSEESTTS--HSRPGSTHTTAFPGSTTMPGVSQESTASH----SSPGSTDTTLSP--- 1070

Query: 2744 NPVPVSETNESSIVERTPFSSSSSSKHSSPSGTVAARVTPFNYNPS---PRKSSADSTSA 2800
                   T  SS+         S++ HS P G+    + P N   S      +   S++ 
Sbjct: 1071 -----RSTTASSL------GPESTTFHSGP-GSTETTLLPDNTTASGLLEASTPVHSSTG 1118

Query: 2801 RPSQIPTPVNNNTKKRDSKT 2820
             P    +P  + T++ +S T
Sbjct: 1119 SPRTTLSPAGSTTRQGESTT 1138



 Score = 49.7 bits (117), Expect = 4e-05
 Identities = 132/603 (21%), Positives = 216/603 (35%), Gaps = 93/603 (15%)

Query: 2254 KTPASKSPSEGQTATTSPRGAKPSV------KSELSPVARQTSQIGGSSKAPS---RSGS 2304
            ++ AS S  +    T  P G+ PSV       S +S  + +T+ + GS+  P    +S +
Sbjct: 500  ESKASHSSPDAMATTVLPAGSTPSVLVGDSTPSPISSGSMETTALPGSTTKPGLSEKSTT 559

Query: 2305 RDSTPSRPAQQPLSRPIQSPGRNSIS------PGRNGISPPNKLSQLPRTSSPSTASTKS 2358
              S+P  P    L   + S G +  S      PG    +     + +P  S  STAS  S
Sbjct: 560  FYSSPRSPDTTHLPASMTSSGVSEESTTSHSRPGSTHTTAFPGSTTMPGLSQESTASHSS 619

Query: 2359 SGSGKMSYTSPGRQMSQQNLTKQTGLSKNASS-----IPRSESASKGLNQMN---NGNGA 2410
             G    +  SPG   +     + T       S     +P + +AS GL + +   + +  
Sbjct: 620  PGPTDTTL-SPGSTTASSLGPEYTTFHSRPGSTETTLLPDNTTAS-GLLEASMPVHSSTR 677

Query: 2411 NKKVELSRMSSTKSSGSESDRSERPVLVRQSTFIKEAPSPTLRRKLEESASFESLSPSSR 2470
            +    LS   ST   G  +     P     S   + AP  T    +E S +    SPSS 
Sbjct: 678  SPHTTLSPAGSTTRQGESTTFHSWP----SSNDTRPAPPTTTSAFVEPSTTSHG-SPSSI 732

Query: 2471 PASPTRSQAQTPVLSPSLPDMSLSTHSSVQAGGWRKLPPNLSPTIEY--NDGRPAKRHDI 2528
            P +   +++ T      L + S + HSS          P  + T+ +  +D    +  + 
Sbjct: 733  PTTHISARSTTS----GLVEESTTYHSS----------PGSTQTMHFPESDTTSGRGEES 778

Query: 2529 ARSHSESP---SRLPINRSGTWKREHSKHSSSLPRVSTWRRTGSSSSILSASSESSEKAK 2585
              SHS +    S  P   S   +   S HSS  P  +       SS+    S ES     
Sbjct: 779  TTSHSSTTHTISSAPSTTSALVEEPTSYHSS--PGSTATTHFPDSSTTSGRSEESIASHS 836

Query: 2586 SEDEKHVNSISGTKQSKENQVSAKGTWRKIKENEFSPTNSTSQTVSSGATNGAESKTLIY 2645
            S+D     +I    +S  + +  + T   I     S +  T+    S  T G   ++  +
Sbjct: 837  SQDA--TGTIVLPARSTNSVLLGESTTSPIS----SGSMETTALPGSTTTPGLSERSTTF 890

Query: 2646 QMAPAVSKTEDVWVRIEDCPINNPRSGRSPTGNTPPVIDSVSEKANPNIKDSKDNQAKQN 2705
              +P                  +P +  SP   T      VSE++  +            
Sbjct: 891  HSSP-----------------RSPATTLSPASTTS---SGVSEESTTSHSRPGSTHTTAF 930

Query: 2706 VGNGSVPMRTVGLENRLNSFIQVDAPDQKGTEIKPGQNNPVPVSETNESSIVERTPFSSS 2765
              + + P    GL    +S     +P    T + P       V E   S      P SS 
Sbjct: 931  PDSTTTP----GLSR--HSTTSHSSPGSTDTTLLPASTTTXLVGEPTTS------PISSG 978

Query: 2766 SSSKHSSPSGTVAARVT--PFNYNPSPRKSSADSTSARPSQIPTPVNNNTKKRDSKTDST 2823
            S+   + P  T  A ++     +  SPR  S D+T +  S   + V+  +    S+  ST
Sbjct: 979  STETTALPGSTTTAGLSEKSTTFYSSPR--SPDTTLSPASTTSSGVSEESTTSHSRPGST 1036

Query: 2824 ESS 2826
             ++
Sbjct: 1037 HTT 1039



 Score = 34.7 bits (78), Expect = 1.4
 Identities = 85/384 (22%), Positives = 136/384 (35%), Gaps = 55/384 (14%)

Query: 1177 IDYSLKYATDIPSSQKQSFSFSKSSS--GQSSKTEHMSSSSENTSTPSSNAKRQNQLHPS 1234
            ++ S  Y +   S+Q   F  S ++S  G+ S T H S++   +S PS+ +    +  P+
Sbjct: 747  VEESTTYHSSPGSTQTMHFPESDTTSGRGEESTTSHSSTTHTISSAPSTTSALVEE--PT 804

Query: 1235 SAQSRSGQ------PQKAATCKVSSINQETIQTYCVEDT------PICFSRCSSLSSLSS 1282
            S  S  G       P  + T   S  ++E+I ++  +D       P   +    L   ++
Sbjct: 805  SYHSSPGSTATTHFPDSSTT---SGRSEESIASHSSQDATGTIVLPARSTNSVLLGESTT 861

Query: 1283 AEDEIGCNQTTQEADSANTLQIAEIKEKIGTRSAEDPVSEVPA------VSQHPRTKSSR 1336
            +    G  +TT    S  T  ++E      +       +  PA      VS+   T  SR
Sbjct: 862  SPISSGSMETTALPGSTTTPGLSERSTTFHSSPRSPATTLSPASTTSSGVSEESTTSHSR 921

Query: 1337 --------LQGSSLSSESARHKAVEFSSGAKS-----PSKS-----GAQTPKSPPEHYVQ 1378
                       S+ +   +RH     SS   +     P+ +     G  T         +
Sbjct: 922  PGSTHTTAFPDSTTTPGLSRHSTTSHSSPGSTDTTLLPASTTTXLVGEPTTSPISSGSTE 981

Query: 1379 ETPLMFSRCTSVSSLDS--FESRSIASSVQSEPCSGMVSGIISPSDLPDS-PGQTMPPS- 1434
             T L  S  T+  S  S  F S   +      P S   SG+   S    S PG T   + 
Sbjct: 982  TTALPGSTTTAGLSEKSTTFYSSPRSPDTTLSPASTTSSGVSEESTTSHSRPGSTHTTAF 1041

Query: 1435 -RSKTPPPPPQTAQTKREVPKNKAPTAEKRES-----GPKQAAVNAAVQRVQ--VLPDAD 1486
              S T P   Q +      P +   T   R +     GP+    ++     +  +LPD  
Sbjct: 1042 PGSTTMPGVSQESTASHSSPGSTDTTLSPRSTTASSLGPESTTFHSGPGSTETTLLPDNT 1101

Query: 1487 TLLHFATESTPDGFSCSSSLSALS 1510
            T       STP   S  S  + LS
Sbjct: 1102 TASGLLEASTPVHSSTGSPRTTLS 1125



 Score = 33.5 bits (75), Expect = 3.1
 Identities = 60/276 (21%), Positives = 105/276 (38%), Gaps = 36/276 (13%)

Query: 1177 IDYSLKYATDIPSSQKQSFSFSKSSSGQS--SKTEHMSSSSENTSTPSSNAKRQNQLHPS 1234
            ++ S  Y +   S+Q   F  S ++SG+S  S+T H S++   +S PS+ +    +  P+
Sbjct: 1216 VEESTAYHSSPGSTQTMHFPESSTASGRSEESRTSHSSTTHTISSPPSTTSALVEE--PT 1273

Query: 1235 SAQSRSGQ------PQKAAT---CKVSSINQETIQTYCVEDTPICFSRCSSLS------- 1278
            S  S  G       P+ + T    + S+ +  +  T  +   P  F+    ++       
Sbjct: 1274 SYHSSPGSIATTHFPESSTTSGRSEESTASHSSPDTNGITPLPAHFTTSGRIAESTTFYI 1333

Query: 1279 SLSSAEDEIGCNQTTQEADSANTLQIAEIKEKIGTRSAEDPVSEVPAVSQHPRTKSSRLQ 1338
            S  S E  +    TT    + +T+  +       +RS +  +S     S     + + L 
Sbjct: 1334 SPGSMETTLASTATTPGLSAKSTILYS------SSRSPDQTLSPASMTSSSISGEPTSLY 1387

Query: 1339 GSSLSSESARHKAVEFSSGAKSPSKSGAQTPKSPPEHYVQETPLMFSRCTSVSSLDSF-- 1396
              + S+ +    A   +SG    S +    P S       ET L     T+ S    F  
Sbjct: 1388 SQAESTHTTAFPASTTTSGLSQESTTFHSKPGS------TETTLSPGSITTSSFAQEFTT 1441

Query: 1397 -ESRSIASSVQSEPCSGMVSGIISPS-DLPDSPGQT 1430
              S+  ++     P S  V G+   S     SPG T
Sbjct: 1442 PHSQPGSALSTVSPASTTVPGLSEESTTFYSSPGST 1477


>gi|149944526 additional sex combs like 3 [Homo sapiens]
          Length = 2248

 Score = 60.8 bits (146), Expect = 2e-08
 Identities = 236/1082 (21%), Positives = 369/1082 (34%), Gaps = 177/1082 (16%)

Query: 1777 KPIPQNTEYRTRVRKNADSKNNLNAERVFSDNKDSKKQNLKNNSKVFNDKLPNNEDRVRG 1836
            K IP+ +E        A+S  N + E   +  +D+ +  +  N  +  + LP+ E ++ G
Sbjct: 471  KTIPEFSE-------EAESLTNSHEEPQIAPPEDNLESCVMMNDVL--ETLPHIEVKIEG 521

Query: 1837 SFAFDSPHHYTPIEGTPYCFSRNDSLSSLDFDDDDVDLSREKAELRKAKENKESEAKVTS 1896
                        I+    C S   S SS+    D               E+KESE  V +
Sbjct: 522  KSESPQEEMTVVIDQLEVCDSLIPSTSSMTHVSDT--------------EHKESETAVET 567

Query: 1897 HTELTSNQQSANKTQ----AIAKQPINRGQPKPILQKQSTFPQSS----------KDIPD 1942
             T       S+ + Q     IA     +  P+  L + +   ++S            +P 
Sbjct: 568  STPKIKTGSSSLEGQFPNEGIAIDMELQSDPEEQLSENACISETSFSSESPEGACTSLPS 627

Query: 1943 RGA---ATDEKLQNFAIENTPVCFSHNSSLSSLSDIDQENNNKEN---------EPIKET 1990
             G    +T E+    A   T  C S  SS  +    +Q N+  EN          PI  T
Sbjct: 628  PGGETQSTSEESCTPASLETTFC-SEVSSTENTDKYNQRNSTDENFHASLMSEISPIS-T 685

Query: 1991 EPPDSQGE-----PSKPQASGYAPKSFHVEDTPVC----FSRNSSLSSLSIDSEDDLLQE 2041
             P  S+       P   +AS  +      E +P+      S  SS+SS+ + SE   +  
Sbjct: 686  SPEISEASLMSNLPLTSEASPVSNLPLTSETSPMSDLPLTSETSSVSSMLLTSETTFVS- 744

Query: 2042 CISSAMPKKKKPSRLKGDNEK--HSPRNMGGILGEDLTLDLKDIQRPDSEHGLSPDSENF 2099
              S  +P +  P      NE+  H  R    +  E L+      Q+ +S     P  EN 
Sbjct: 745  --SLPLPSETSPISNSSINERMAHQQRKSPSVSEEPLSP-----QKDESSATAKPLGENL 797

Query: 2100 --DWKAIQEGANSIVSSLHQAAAAACLSRQASSDSDSILSLKSGISLGSPFHLT-PDQEE 2156
                K +      I+ S    A  A  S    + + S  + KS +    P+  + P+   
Sbjct: 798  TSQQKNLSNTPEPIIMSSSSIAPEAFPSEDLHNKTLSQQTCKSHVDTEKPYPASIPELAS 857

Query: 2157 KPFTSNKGPRILKPGEKSTLETK---KIESESKGIKGGKKVYKSLITGKVRSNSEISGQM 2213
                  K   +L+  EK  L +     + SE    KG +     L + K++    IS   
Sbjct: 858  TEMIKVKNHSVLQRTEKKVLPSPLELSVFSEGTDNKGNE-----LPSAKLQDKQYISSVD 912

Query: 2214 KQPLQANMPSISRGRTMIHIPGVRNSSSSTSPVSKKGPPLKTPASKSPSEGQTATTSPRG 2273
            K P        SR +T  H  G   S   TS  SK   P K+P     +E + +  S R 
Sbjct: 913  KAPFSEG----SRNKT--HKQGSTQSRLETSHTSKSSEPSKSPDGIR-NESRDSEISKR- 964

Query: 2274 AKPSVKSELSPVARQTSQIGGSSKAPSRSGSRDSTPSRPAQQPLSRPIQSPGRNSISPGR 2333
             K + +        + ++I       + S S   +P    Q P   P   P +  +S   
Sbjct: 965  -KTAEQHSFGICKEKRARIEDDQSTRNISSS---SPPEKEQPPREEPRVPPLKIQLSK-- 1018

Query: 2334 NGISPPNKLSQLPRTSSPSTASTKSSGSGKMSYTSPGRQMSQQNLTKQTGLSKNASSIPR 2393
              I PP  +   P +   S AST +S SG       GR    + L      ++ A +   
Sbjct: 1019 --IGPPFIIKSQPVSKPESRASTSTSVSG-------GRNTGARTLADIKARAQQARA--- 1066

Query: 2394 SESASKGLNQMNNGNGANKKVELSRMSSTKSSGSESDRSERPVLVRQSTFIKEAPSPTLR 2453
                     Q      A      S +S    S  E  ++      R    IKE     L 
Sbjct: 1067 ---------QREAAAAAAVAAAASIVSGAMGSPGEGGKT------RTLAHIKEQTKAKLF 1111

Query: 2454 RKLEESASFESLSPSSRPASPTRSQAQTPVLS-PSLPDMSLSTHSSVQAGGWRKLPPNLS 2512
             K +  A     S  +R   P  S+   P L   S P+  +   + V       + PN  
Sbjct: 1112 AKHQARAHLFQTSKETRLPPPLSSKEGPPNLEVSSTPETKMEGSTGVII-----VNPN-- 1164

Query: 2513 PTIEYNDGRPAKRHDIARSHSESPSRLPINRSGTWKREHSKHSSSLPRVSTWRRTGSSSS 2572
                             RS S   + L   R  T   + S + S LP  +T     SS  
Sbjct: 1165 ----------------CRSPSNKSAHL---RETTTVLQQSLNPSKLPETATDLSVHSSDE 1205

Query: 2573 ILSASSESSEKAKSEDEKHVNSIS--GTKQSKENQVSAKGTWRKIKENEF-SPTNSTSQT 2629
             +   S  SEK  S      +S+     K S    V +      IKE+ F S  + +S  
Sbjct: 1206 NIPV-SHLSEKIVSSTSSENSSVPMLFNKNSVPVSVCSTAISGAIKEHPFVSSVDKSSVL 1264

Query: 2630 VSSGATNGAESKTLIYQMAPAVSKTEDVWVR-----IEDCPINNPRSGRSPTGNTPPVID 2684
            +S  + N   S   I  M   +  T+   +      IE  PI+    G S + +      
Sbjct: 1265 MSVDSANTTISACNI-SMLKTIQGTDTPCIAIIPKCIESTPISATTEGSSISSSMDDKQL 1323

Query: 2685 SVSEKANPNIKDSKDNQAKQNVGNGSVPMRTVGLENRLNSFIQVDAPDQKGTEIKPGQNN 2744
             +S  +  N+  ++           SVP  ++G      S   V  P        P +  
Sbjct: 1324 LISSSSASNLVSTQYT---------SVPTPSIGNNLPNLSTSSVLIPPMGINNRFPSEKI 1374

Query: 2745 PVPVSETNESSIVERTPFSSSSSSKHSSPSGTVAARVT---------PFNYNPSPRKSSA 2795
             +P SE   +  +  T  ++ S S   + + ++ A  T           N   SP K SA
Sbjct: 1375 AIPGSEEQATVSMGTTVRAALSCSDSVAVTDSLVAHPTVAMFTGNMLTINSYDSPPKLSA 1434

Query: 2796 DS 2797
            +S
Sbjct: 1435 ES 1436



 Score = 33.1 bits (74), Expect = 4.0
 Identities = 52/268 (19%), Positives = 104/268 (38%), Gaps = 47/268 (17%)

Query: 2569 SSSSILSASSESSEKAKSEDEKHVNSISGTKQSKENQVSAKGTWRKIKENEFSPTNSTSQ 2628
            S+SSI    +    K+ S  E+ ++      Q  E+  +AK     +   + + +N+   
Sbjct: 756  SNSSINERMAHQQRKSPSVSEEPLSP-----QKDESSATAKPLGENLTSQQKNLSNTPEP 810

Query: 2629 TVSSGATNGAESKTLIYQMAPAVSKTEDVWVRIEDCPINNPRSGRSPTGNTPPVIDSVSE 2688
             + S ++           +AP    +ED+  +       + ++ +S      P   S+ E
Sbjct: 811  IIMSSSS-----------IAPEAFPSEDLHNKTL-----SQQTCKSHVDTEKPYPASIPE 854

Query: 2689 KANPNIKDSKDNQAKQNVGNGSVPMRTVGLENRLNSFIQVDAPDQKGTEIKPGQNNPVPV 2748
             A+  +   K++   Q      +P       + L   +  +  D KG E+   +     +
Sbjct: 855  LASTEMIKVKNHSVLQRTEKKVLP-------SPLELSVFSEGTDNKGNELPSAK-----L 902

Query: 2749 SETNESSIVERTPFSSSSSSKHSSPSGTVAARVTPFNYNPSPRKSSADSTSARPSQIPTP 2808
             +    S V++ PFS  S +K +   G+  +R+          ++S  S S+ PS+ P  
Sbjct: 903  QDKQYISSVDKAPFSEGSRNK-THKQGSTQSRL----------ETSHTSKSSEPSKSPDG 951

Query: 2809 VNNNTKKRD---SKTDSTESSGTQSPKR 2833
            + N ++  +    KT    S G    KR
Sbjct: 952  IRNESRDSEISKRKTAEQHSFGICKEKR 979


>gi|207113164 Treacher Collins-Franceschetti syndrome 1 isoform f
            [Homo sapiens]
          Length = 1412

 Score = 59.3 bits (142), Expect = 5e-08
 Identities = 275/1438 (19%), Positives = 488/1438 (33%), Gaps = 203/1438 (14%)

Query: 1131 QEDDYEDDKPTNYSERYSEEEQHEEEERPTNYSIKY-------NEEKRHVDQPIDYSLKY 1183
            +ED     K T  S+  S  E  EEEE     + K        N      D P     K 
Sbjct: 66   EEDAALQAKKTRVSDPISTSESSEEEEEAEAETAKATPRLASTNSSVLGADLPSSMKEKA 125

Query: 1184 ATDIPSSQKQSFSFSKSSSGQSSKTEHMSSSSENTSTPSSNAKRQNQLHPSSAQSRSGQP 1243
              +   + K   S    ++G++        S   ++ PS+N    ++     +    G  
Sbjct: 126  KAETEKAGKTGNSMPHPATGKTVANLLSGKSPRKSAEPSANTTLVSETEEEGSVPAFGAA 185

Query: 1244 QKAATCKVSSINQETIQTYCVEDTPICFSRCSSLSSLSSAEDEIGCNQTTQEADSANTLQ 1303
             K         +  +      EDT             SS+ DE        E        
Sbjct: 186  AKPGMVSAGQADSSS------EDT-------------SSSSDETDVEVKASEKILQVRAA 226

Query: 1304 IAEIKEKIGTRSAEDPVSEVPAVSQHPR-------TKSSRLQGSSLSSESARHKAVEFSS 1356
             A  K   G  +   P  +  AV+   +       ++SS  + S    E+   KA+  + 
Sbjct: 227  SAPAKGTPGKGATPAPPGKAGAVASQTKAGKPEEDSESSSEESSDSEEETPAAKALLQAK 286

Query: 1357 GAKSPSKSGAQT---PKSPPEHYVQETPLMFSRCTSVSSLDSFESRSIASSVQSE----- 1408
             +   S+ GA +    +SP +      P       + +     E  S +SS +S+     
Sbjct: 287  ASGKTSQVGAASAPAKESPRKGAAPAPPGKTGPAVAKAQAGKREEDSQSSSEESDSEEEA 346

Query: 1409 PCSGMVSGIISPSDLPDSPGQTMPPSRSKTPPPPPQT--AQTKREVPKNKAPTAEKRESG 1466
            P     SG         +P +   P +   P PP +T  A  + +V K +  +    E  
Sbjct: 347  PAQAKPSGKAPQVRAASAPAKE-SPRKGAAPAPPRKTGPAAAQVQVGKQEEDSRSSSEES 405

Query: 1467 PKQAAVNAAVQRVQVLP--------DADTL----LHFATESTPDGFSCSSSLSA------ 1508
                   AA+   QV P         A T+    L       P G    ++ SA      
Sbjct: 406  DSDREALAAMNAAQVKPLGKSPQVKPASTMGMGPLGKGAGPVPPGKVGPATPSAQVGKWE 465

Query: 1509 ----LSLDEPFIQKDVEL-RIMPPVQENDNGNETESEQPKESNENQ---------EKEAE 1554
                 S +E     D E+   + P QE   GN  +++      +           + +AE
Sbjct: 466  EDSESSSEESSDSSDGEVPTAVAPAQEKSLGNILQAKPTSSPAKGPPQKAGPVAVQVKAE 525

Query: 1555 KTIDSEKDLLDDSDDDDIEILEECIISAMPTKSSRKAKKPAQTASKLPPPVARKPSQLPV 1614
            K +D+ +   + SD  D E       +AM    ++ A K  QT +       +K +    
Sbjct: 526  KPMDNSESSEESSDSADSEEAP----AAMTAAQAKPALKIPQTKA-----CPKKTNTTAS 576

Query: 1615 YKLLPSQNRLQ-PQKHVSFT-PGDDMPRVYCVEGTPINFSTATSLSDLTIESPPNELAAG 1672
             K+ P +   Q P+K  + T P    P V      P   S+++  SD   E     LA  
Sbjct: 577  AKVAPVRVGTQAPRKAGTATSPAGSSPAVAGGTQRPAEDSSSSEESD--SEEEKTGLAVT 634

Query: 1673 EGVRGGAQSGEFEKRDTIPTE---GRSTDEAQGGKTSSVTIPELDDNKAEEGDILAECIN 1729
             G       G   K  ++P +   G+ T     GKT   T+ ++   K E+ +   E  +
Sbjct: 635  VGQAKSVGKGLQVKAASVPVKGSLGQGTAPVLPGKTGP-TVTQVKAEKQEDSESSEEESD 693

Query: 1730 SAMPKGKSHKPFRVKKIMDQVQ-----------QASASSSAPNKNQLDGKKKKPTSP--V 1776
            S   +  +  P +VK  + + Q            A  + SAP K      + K  SP  V
Sbjct: 694  S---EEAAASPAQVKTSVKKTQAKANPAAARAPSAKGTISAPGKVVTAAAQAKQRSPSKV 750

Query: 1777 KPIPQNTEYRTRVRKNADSKNNLN------AERVFSDNKDSKKQNLKNNSK-----VFND 1825
            KP  +N +  T + +   S  ++       A+      +DS     +++S+     +   
Sbjct: 751  KPPVRNPQNSTVLARGPASVPSVGKAVATAAQAQTGPEEDSGSSEEESDSEEEAETLAQV 810

Query: 1826 KLPNNEDRVRGSFAFDSPHHYTPIEG-TPYCFSRNDSLSSLDFDDDDVDLSREKAELRKA 1884
            K      ++R + A   P   +P +G  P    +    ++     DD   S E+++    
Sbjct: 811  KPSGKTHQIRAALA---PAKESPRKGAAPTPPGKTGPSAAQAGKQDDSGSSSEESD---- 863

Query: 1885 KENKESEAKVTSHTEL------TSNQQSANKTQAIAKQPINRGQPKPILQKQSTFPQSSK 1938
              + E+ A VTS   +          +S     A   Q      P+     +ST   SS 
Sbjct: 864  -SDGEAPAAVTSAQVIKPPLIFVDPNRSPAGPAATPAQAQAASTPRKARASESTARSSSS 922

Query: 1939 DIPDRGAATDEKLQNFAIENTPVCF-SHNSSLSSLSDIDQENNNKENEPI---KETEPPD 1994
            +  D       +     I    V   + +  ++  + +   +++KE+  I   K+ E P 
Sbjct: 923  ESEDEDVIPATQCLTPGIRTNVVTMPTAHPRIAPKASMAGASSSKESSRISDGKKQEGPA 982

Query: 1995 SQGEPSKPQASGYAPKSFHV-------EDTPVCFSRNSSLSSLSIDSEDDLLQECISSAM 2047
            +Q     P +      +  V          PV  ++ SS     +DS    L      A 
Sbjct: 983  TQVSKKNPASLPLTQAALKVLAQKASEAQPPVARTQPSS----GVDSAVGTL-----PAT 1033

Query: 2048 PKKKKPSRLKGDNEKHSPRNMGGILGEDLTLDLKDIQRPDSEHGLSPDSENFDWKAIQEG 2107
              +    + KG N+   P+ +  +       +  D    DS    S   E+ +     + 
Sbjct: 1034 SPQSTSVQAKGTNKLRKPK-LPEVQQATKAPESSD-DSEDSSDSSSGSEEDGEGPQGAKS 1091

Query: 2108 ANSIVSSLHQAAAAACLSRQASSDSDSILSLKSGISLGSPFHLTPDQEEKPFTSNKG-PR 2166
            A+++V               A S  D +++    +  G   ++TP        ++K  P+
Sbjct: 1092 AHTLVGPTPSRTETLVEETAAESSEDDVVAPSQSLLSG---YMTPGLTPANSQASKATPK 1148

Query: 2167 I-LKPGEKSTLETKKIESESKGIKGGKKVYKSLITGKVRSNSEISGQMKQPLQANMPSIS 2225
            +   P   STL  K      +  K  +     +++ K       SG    P ++  P   
Sbjct: 1149 LDSSPSVSSTLAAKDDPDGKQEAKPQQAA--GMLSPKTGGKEAASG--TTPQKSRKPK-- 1202

Query: 2226 RGRTMIHIPGVRNSSSSTSPVSKKGPPLKTPASKSPSEGQTATTSPRGAKPSVKSELSPV 2285
                     G  N  +ST  +               +E Q      + +   V +EL  +
Sbjct: 1203 --------KGAGNPQASTLALQSNITQCLLGQPWPLNEAQV-----QASVVKVLTEL--L 1247

Query: 2286 ARQTSQIGGSSKAPSRSGSRDSTPSRPAQQPLSRPIQSPGRNSISPGRNGISPPNKLSQL 2345
             ++  ++  ++K  SR G           QP +R  +S  +  +  G  G          
Sbjct: 1248 EQERKKVVDTTKESSRKGWESRKRKLSGDQPAARTPRSKKKKKLGAGEGG---------- 1297

Query: 2346 PRTSSPSTASTKSSGSGKMSYTSPGRQMSQQNLTKQTG---LSKNASSIPRSESASKGLN 2402
              + SP   ST S G  K       R  +  ++ ++ G   L    +     E   KG+ 
Sbjct: 1298 EASVSPEKTSTTSKGKAK-------RDKASGDVKEKKGKGSLGSQGAKDEPEEELQKGMG 1350

Query: 2403 QMNNGNGANKKVELSRMSSTKSSGSESDRSERPVLVRQSTFIKEAPSPTLRRKLEESA 2460
             +  G+ +N K +  +  S K    +  + ++    + ST   E+PS   ++K +++A
Sbjct: 1351 TVEGGDQSNPKSKKEKKKSDKRKKDKEKKEKKKKAKKASTKDSESPSQKKKKKKKKTA 1408



 Score = 50.8 bits (120), Expect = 2e-05
 Identities = 153/868 (17%), Positives = 292/868 (33%), Gaps = 113/868 (13%)

Query: 2045 SAMPKKKKPSRLKGDNEKHSPR---NMGGILGEDLTLDLKDIQRPDSEHGLSPDSENFDW 2101
            S     ++    + +  K +PR       +LG DL   +K+  + ++E      +     
Sbjct: 83   STSESSEEEEEAEAETAKATPRLASTNSSVLGADLPSSMKEKAKAETEKAGKTGNSMPHP 142

Query: 2102 KAIQEGANSIVSSLHQAAAAACLSRQASSDSDSILSLKSGISLGSPFHLTPDQ-----EE 2156
               +  AN +     + +A    +    S+++   S+ +  +   P  ++  Q     E+
Sbjct: 143  ATGKTVANLLSGKSPRKSAEPSANTTLVSETEEEGSVPAFGAAAKPGMVSAGQADSSSED 202

Query: 2157 KPFTSNKGPRILKPGEKSTLETKKIESESKGIKG--------GKK--VYKSLITGKVRSN 2206
               +S++    +K  EK  L+ +   + +KG  G        GK   V      GK   +
Sbjct: 203  TSSSSDETDVEVKASEK-ILQVRAASAPAKGTPGKGATPAPPGKAGAVASQTKAGKPEED 261

Query: 2207 SEISGQMKQPLQANMPSISRGRTMIHIPGVRNSSSSTSPVSKKGPPLKTPASKSPSEGQT 2266
            SE S +     +   P+    + ++       +S  TS V     P K    K  +    
Sbjct: 262  SESSSEESSDSEEETPA---AKALLQA----KASGKTSQVGAASAPAKESPRKGAAPAPP 314

Query: 2267 ATTSPRGAKPSVKSELSPVARQTSQIGGSSKAPSRSGSRDSTPS-RPAQQPLSRPIQSPG 2325
              T P  AK             + +     +AP+++      P  R A  P     +SP 
Sbjct: 315  GKTGPAVAKAQAGKREEDSQSSSEESDSEEEAPAQAKPSGKAPQVRAASAPAK---ESPR 371

Query: 2326 RNSISPGRNGISPPNKLSQLPRTSSPSTASTKSSGS----------------GKMSYTSP 2369
            + +         P     Q+ +    S +S++ S S                GK     P
Sbjct: 372  KGAAPAPPRKTGPAAAQVQVGKQEEDSRSSSEESDSDREALAAMNAAQVKPLGKSPQVKP 431

Query: 2370 GRQMSQQNLTKQTGLSKNASSIPRSESASKGLNQMNNGNGANKKVELSRMSSTKSSGSES 2429
               M    L K  G        P + SA  G  + ++ + + +  + S      +     
Sbjct: 432  ASTMGMGPLGKGAGPVPPGKVGPATPSAQVGKWEEDSESSSEESSDSSDGEVPTAVAPAQ 491

Query: 2430 DRSERPVLVRQSTFIKEAPSP----------TLRRKLEESASFESLSPSS----RPASPT 2475
            ++S   +L  + T       P             + ++ S S E  S S+     PA+ T
Sbjct: 492  EKSLGNILQAKPTSSPAKGPPQKAGPVAVQVKAEKPMDNSESSEESSDSADSEEAPAAMT 551

Query: 2476 RSQAQTPVLSPSLPDMSLSTHSSVQA--------------GGWRKLPPNLSPTIEYNDGR 2521
             +QA+  +  P        T+++  A               G    P   SP +     R
Sbjct: 552  AAQAKPALKIPQTKACPKKTNTTASAKVAPVRVGTQAPRKAGTATSPAGSSPAVAGGTQR 611

Query: 2522 PAKRHDIARSHSESPSR-------LPINRSGTWKREHSKHSSSLPRVSTWRRTGSSSSIL 2574
            PA   + + S  ES S        + + ++ +  +     ++S+P V      G++  + 
Sbjct: 612  PA---EDSSSSEESDSEEEKTGLAVTVGQAKSVGKGLQVKAASVP-VKGSLGQGTAPVLP 667

Query: 2575 SASSESSEKAKSEDEKHVNSISGTKQSKENQVSAKGTWRKIKENEFSPTNSTSQTVSSGA 2634
              +  +  + K+E ++   S      S+E   S       +K+ +     + ++  S+  
Sbjct: 668  GKTGPTVTQVKAEKQEDSESSEEESDSEEAAASPAQVKTSVKKTQAKANPAAARAPSAKG 727

Query: 2635 TNGAESKTL-----IYQMAPAVSKTEDVWVRIEDCPINNPRS----GRSPTGNTPPVIDS 2685
            T  A  K +       Q +P+  K           P+ NP++     R P  + P V  +
Sbjct: 728  TISAPGKVVTAAAQAKQRSPSKVKP----------PVRNPQNSTVLARGP-ASVPSVGKA 776

Query: 2686 VSEKANPNIKDSKDNQAKQNVGNGSVPMRTVGLENRLNSFIQVDAPDQKGTEIKPGQNNP 2745
            V+  A       +D+ + +   +      T+          Q+ A      E       P
Sbjct: 777  VATAAQAQTGPEEDSGSSEEESDSEEEAETLAQVKPSGKTHQIRAALAPAKESPRKGAAP 836

Query: 2746 VPVSETNESSIVERTPFSSSSSSKHSSPSGTVAARVTPFN--------YNPSPRKSSADS 2797
             P  +T  S+        S SSS+ S   G   A VT            +P+   +   +
Sbjct: 837  TPPGKTGPSAAQAGKQDDSGSSSEESDSDGEAPAAVTSAQVIKPPLIFVDPNRSPAGPAA 896

Query: 2798 TSARPSQIPTPVNNNTKKRDSKTDSTES 2825
            T A+     TP      +  +++ S+ES
Sbjct: 897  TPAQAQAASTPRKARASESTARSSSSES 924



 Score = 38.9 bits (89), Expect = 0.073
 Identities = 71/329 (21%), Positives = 123/329 (37%), Gaps = 47/329 (14%)

Query: 2540 PINRSGTWKREHSKHSSSLPRVSTWRRTGSSSSILSASSESS--EKAKSEDE---KHVNS 2594
            PI+ S + + E    + +    +T R   ++SS+L A   SS  EKAK+E E   K  NS
Sbjct: 81   PISTSESSEEEEEAEAETAK--ATPRLASTNSSVLGADLPSSMKEKAKAETEKAGKTGNS 138

Query: 2595 I--SGTKQSKENQVSAKGTWRKIKENEFSPTNSTSQTVSSGATNGAESKTLIYQMAPAVS 2652
            +    T ++  N +S K   +  + +  +   S ++   S    GA +K  +     A S
Sbjct: 139  MPHPATGKTVANLLSGKSPRKSAEPSANTTLVSETEEEGSVPAFGAAAKPGMVSAGQADS 198

Query: 2653 KTED------------------VWVRIEDCPI-NNPRSGRSPT--GNTPPVIDSV----- 2686
             +ED                  + VR    P    P  G +P   G    V         
Sbjct: 199  SSEDTSSSSDETDVEVKASEKILQVRAASAPAKGTPGKGATPAPPGKAGAVASQTKAGKP 258

Query: 2687 SEKANPNIKDSKDNQAKQNVGNGSVPMRTVGLENRLN--SFIQVDAPDQKGTEIKPGQNN 2744
             E +  + ++S D++ +       +  +  G  +++   S    ++P +      PG+  
Sbjct: 259  EEDSESSSEESSDSEEETPAAKALLQAKASGKTSQVGAASAPAKESPRKGAAPAPPGKTG 318

Query: 2745 PVPV-------SETNESSIVERTPFSSSSSSKHSSPSGTV-AARVTPFNYNPSPRKSSAD 2796
            P           E ++SS  E    S   +   + PSG     R        SPRK +A 
Sbjct: 319  PAVAKAQAGKREEDSQSSSEESD--SEEEAPAQAKPSGKAPQVRAASAPAKESPRKGAAP 376

Query: 2797 STSARPSQIPTPVNNNTKKRDSKTDSTES 2825
            +   +       V    ++ DS++ S ES
Sbjct: 377  APPRKTGPAAAQVQVGKQEEDSRSSSEES 405


>gi|112821681 G protein-regulated inducer of neurite outgrowth 1 [Homo
            sapiens]
          Length = 1008

 Score = 57.8 bits (138), Expect = 2e-07
 Identities = 129/593 (21%), Positives = 226/593 (38%), Gaps = 78/593 (13%)

Query: 1960 PVCFSHNSSLS-------SLSDIDQENNNKENEPIKETEPPDSQGEPSKPQASGYAPKSF 2012
            P+C S   ++S       SL  +D  +++K +      E P   G+     +   AP S 
Sbjct: 219  PLCSSKTYTVSPRKEDPGSLRKVDPVSSDKVDPVFPRKEEPRYSGKEHPVSSEKVAPTSA 278

Query: 2013 HVEDTPVCFSRNSSLSSLSIDSEDDLLQECISSAMPKKKKPSRL----KGDNEKHSPRNM 2068
               D  +   R+   S  +    D +  E + SA   K +P  L     G + K+ P + 
Sbjct: 279  EKVDLVLSGKRDPGPSGKA----DPMPLESMDSASTGKTEPGLLGKLIPGSSGKNGPVSS 334

Query: 2069 G----GILG--EDLTLDLKDIQRPDSEHGLSPDSENFDWKAIQEGANS----IVSSLHQA 2118
            G    G LG  +   L + D     +   +    E+  +    + A+S     VS     
Sbjct: 335  GTGAPGSLGRLDPTCLGMADPASVGNVETVPATKEDSRFLGKMDPASSGEGRPVSGHTDT 394

Query: 2119 AAAACLSRQASSDSDSILSLK-SGISLGS--------PFHLTPDQEEKPFTSNKGPRILK 2169
             A+A     +  + D + S K   +SLG         P  L+P Q E+      G   + 
Sbjct: 395  TASAKTDLTSLKNVDPMSSGKVDPVSLGKMDPMCSGKPELLSPGQAERVSVGKAGT--VS 452

Query: 2170 PGEKSTLETKKIESESKGIKGGKKVYKSLITGKVRSNSEISGQMKQPLQANMPSISRGRT 2229
            PG++  + +++ +  S G         S  T   + N E SG+   P+ +  P   R   
Sbjct: 453  PGKEDPVSSRREDPISAG---------SRKTSSEKVNPESSGKTN-PVSSG-PGDPRSLG 501

Query: 2230 MIHIPGVRNSSSSTSPVSKKGPPLKTPASKSPSEGQTATTSPRGAKPSVKSELSPVARQT 2289
                P    +  +T     KG PL +  +   + G+ A T+   A+P    +  PV++  
Sbjct: 502  TAGPPSAVKAEPATGG---KGDPLSSEKAGLVASGKAAPTASGKAEPLAVGKEDPVSKGK 558

Query: 2290 SQIGGSSKAPSRS-GSRDSTPSRPAQQPLSRPIQSPGRNSISPGRNGISPPNKLSQLPRT 2348
            +  G S +  S S G   STP +        P+ S   + +S G+    P  K+  LP  
Sbjct: 559  ADAGPSGQGDSVSIGKVVSTPGKTV------PVPSGKVDPVSLGKAEAIPEGKVGSLPLE 612

Query: 2349 SSPSTASTKSS--GSGKMSYTSPGRQMSQQNLTKQTGLSK--NASSIPRSESASKGLNQM 2404
                  +TK+    SGK    S G+  ++  L  Q G +    A ++   +   +   ++
Sbjct: 613  KGSPVTTTKADPRASGKAQPQSGGK--AETKLPGQEGAAAPGEAGAVCLKKETPQASEKV 670

Query: 2405 NNG---------NGANKKVELSRMSSTKSSGSESDRSERPVLVRQSTFIKEAPSPTLRRK 2455
            + G         +G  + V L +  S  S  +ES    + V +   +  K  PS +  R+
Sbjct: 671  DPGSCRKAEPLASGKGEPVSLGKADSAPSRKTESPSLGKVVPL---SLEKTKPSSS-SRQ 726

Query: 2456 LEESASFESLSPSSRPASPTRSQAQTPVLSPSLPDMSLSTHSSVQAGGWRKLP 2508
            L+  A   + SP     S  R + +   +S +  + S      ++A G  + P
Sbjct: 727  LDRKALGSARSPEGARGSEGRVEPKAEPVSST--EASSLGQKDLEAAGAERSP 777



 Score = 39.3 bits (90), Expect = 0.056
 Identities = 65/321 (20%), Positives = 118/321 (36%), Gaps = 32/321 (9%)

Query: 1188 PSSQKQSFSFSKSSSGQSSKTEHMSSSSENTSTPSSNAK-----RQNQLHPSSAQSR-SG 1241
            PS+ K   +        SS+   + +S +   T S  A+     +++ +    A +  SG
Sbjct: 506  PSAVKAEPATGGKGDPLSSEKAGLVASGKAAPTASGKAEPLAVGKEDPVSKGKADAGPSG 565

Query: 1242 QPQKAATCKVSSINQETIQTYCVEDTPICFSRCSSL--SSLSSAEDEIGCNQTTQEADS- 1298
            Q    +  KV S   +T+     +  P+   +  ++    + S   E G   TT +AD  
Sbjct: 566  QGDSVSIGKVVSTPGKTVPVPSGKVDPVSLGKAEAIPEGKVGSLPLEKGSPVTTTKADPR 625

Query: 1299 ANTLQIAEIKEKIGTRSAEDPVSEVPAVSQHPRTKSSRLQGSSLSSESARHKAVEFSSGA 1358
            A+     +   K  T+      +  P  +     K    Q S      +  KA   +SG 
Sbjct: 626  ASGKAQPQSGGKAETKLPGQEGAAAPGEAGAVCLKKETPQASEKVDPGSCRKAEPLASGK 685

Query: 1359 KSPSKSG----AQTPKSPPEHYVQETPLMFSRCTSVSSLDSFESRSIASS---------- 1404
              P   G    A + K+      +  PL   +    SS    + +++ S+          
Sbjct: 686  GEPVSLGKADSAPSRKTESPSLGKVVPLSLEKTKPSSSSRQLDRKALGSARSPEGARGSE 745

Query: 1405 ----VQSEPCSGMVSGIISPSDLPDSPGQTMPPSRSKTPPPPPQTAQTKREVP--KNKAP 1458
                 ++EP S   +  +   DL  +  +  P   +  PPP P+T     + P  +  AP
Sbjct: 746  GRVEPKAEPVSSTEASSLGQKDLEAAGAERSPCPEAAAPPPGPRTRDNFTKAPSWEASAP 805

Query: 1459 TAEKRESGPK---QAAVNAAV 1476
               + ++G +   QA V+ AV
Sbjct: 806  PPPREDAGTQAGAQACVSVAV 826


>gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens]
          Length = 1020

 Score = 56.6 bits (135), Expect = 3e-07
 Identities = 112/580 (19%), Positives = 210/580 (36%), Gaps = 88/580 (15%)

Query: 2155 EEKPFTSNKGPRILKPGEKSTLETKKIESES---KGIKGGKKVYKS-----LITGKVRSN 2206
            EE+   +     + +  EK   E +  E E    +  +GG++  KS       + +  + 
Sbjct: 458  EEQTEETQVTEEVTEEEEKEAKEEEGKEEEGGEEEEAEGGEEETKSPPAEEAASPEKEAK 517

Query: 2207 SEISGQMKQPLQANMPSISRGRTMIHIPGVRNSSSSTSPVSKKGPPLKTPA---SKSPSE 2263
            S +  + K P +A  P     ++   +     + S     +K  P  K+P    +KSP+E
Sbjct: 518  SPVKEEAKSPAEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPPEAKSPEKEEAKSPAE 577

Query: 2264 GQTA----------------TTSPRGAKPSVKSELSPVARQTSQIGGSSKAPSRSGSRDS 2307
             ++                   SP  AK  VK E    A   S +   +K+P+   S + 
Sbjct: 578  VKSPEKAKSPAKEEAKSPAEAKSPEKAKSPVKEEAKSPAEAKSPVKEEAKSPAEVKSPEK 637

Query: 2308 TPSRPAQQPLSRPIQSPGRNSISPGRNGISPPNKLSQLPRTSSPSTASTKSSGSGKMSYT 2367
                 A+ P     +SP   + SP +     P K        SP  A  KS    K    
Sbjct: 638  -----AKSPTKEEAKSP-EKAKSPEKEEAKSPEK------AKSPVKAEAKSPEKAK---- 681

Query: 2368 SPGRQMSQQNLTKQTGLSKNASSIPRSESASKGLNQMNNGNGANKKVELSRMSSTKSSGS 2427
            SP +  ++     ++ + + A S  +++S  K             K      S  K    
Sbjct: 682  SPVKAEAKSPEKAKSPVKEEAKSPEKAKSPVK----------EEAKSPEKAKSPVKEEAK 731

Query: 2428 ESDRSERPVLVRQSTFIKEAPSPTLRRKLEESASFESLSPSSRPASPTRSQAQTPVLSPS 2487
              ++++ PV        +EA SP   +  E++ + +  SP ++  +P + +A++P  +  
Sbjct: 732  TPEKAKSPVK-------EEAKSPEKAKSPEKAKTLDVKSPEAK--TPAKEEARSP--ADK 780

Query: 2488 LPDMSLS-THSSVQAGGWRKLPPNLSPTIEYNDGRPAKRHDIARSHSESPSRLPINRSGT 2546
             P+ + S     V++    K P  L    +  +    K+ ++     E      +     
Sbjct: 781  FPEKAKSPVKEEVKSPEKAKSP--LKEDAKAPEKEIPKKEEVKSPVKEEEKPQEVKVKEP 838

Query: 2547 WKREHSKHSSSLPRVSTWRRTGSSSSILSASSESSEKAKSEDEKHVNSISGTKQSKENQV 2606
             K+   + + + P+    +     S    A  + + K K E++K        ++ KE++V
Sbjct: 839  PKKAEEEKAPATPKTEEKK----DSKKEEAPKKEAPKPKVEEKKE----PAVEKPKESKV 890

Query: 2607 SAKGTWRKIKENEFSPTNSTSQTVSSGATNGAESKTLIYQMAPAVSKTEDVWVRIEDCPI 2666
             AK    + K+   +P               A +K  + + A    KTE      +D   
Sbjct: 891  EAKKEEAEDKKKVPTPEKE------------APAKVEVKEDAKPKEKTEVAKKEPDDAKA 938

Query: 2667 NNPRSGRSPTGNTPPVIDSVSEKA-NPNIKDSKDNQAKQN 2705
              P          P   D+  EKA  P  K   + +AK++
Sbjct: 939  KEPSKPAEKKEAAPEKKDTKEEKAKKPEEKPKTEAKAKED 978



 Score = 55.1 bits (131), Expect = 1e-06
 Identities = 107/563 (19%), Positives = 204/563 (36%), Gaps = 76/563 (13%)

Query: 1529 QENDNGNETESEQPKESNENQEKEAEKTIDSEKDLLDDSDDDDIEILEECIISAMPTKSS 1588
            +E + G E     P E   + EKEA+  +  E     ++   + E  +    S    KS 
Sbjct: 492  EEAEGGEEETKSPPAEEAASPEKEAKSPVKEEAKSPAEAKSPEKEEAK----SPAEVKSP 547

Query: 1589 RKAKKPAQTASKLPPPV-------ARKPSQL--PVYKLLPSQNRLQ-------------P 1626
             KAK PA+  +K PP         A+ P+++  P     P++   +             P
Sbjct: 548  EKAKSPAKEEAKSPPEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPAEAKSPEKAKSP 607

Query: 1627 QKHVSFTPGDDMPRVYCVEGTPINFSTATSLSDLTIESPPNELAAGEGVRGGAQSGEFEK 1686
             K  + +P +    V     +P    +       T E   +   A    +  A+S E + 
Sbjct: 608  VKEEAKSPAEAKSPVKEEAKSPAEVKSPEKAKSPTKEEAKSPEKAKSPEKEEAKSPE-KA 666

Query: 1687 RDTIPTEGRSTDEAQGGKTSSVTIPELDDNKAEEGDILAECINSAMPKGKSHKPFRVKKI 1746
            +  +  E +S ++A+    +    PE   +  +E     E   S + K ++  P + K  
Sbjct: 667  KSPVKAEAKSPEKAKSPVKAEAKSPEKAKSPVKEEAKSPEKAKSPV-KEEAKSPEKAKSP 725

Query: 1747 MDQVQQASASSSAPNKNQLDG--KKKKPTSPVKPIPQNTEYRTRVRKNADSKNNLNAERV 1804
            + +  +    + +P K +     K K P        ++ E +T  ++ A S  +   E+ 
Sbjct: 726  VKEEAKTPEKAKSPVKEEAKSPEKAKSPEKAKTLDVKSPEAKTPAKEEARSPADKFPEKA 785

Query: 1805 FSDNKDSKKQNLKNNSKVFND-KLPNNEDRVRGSFAFDSPHHYTPIEGTPYCFSRNDSLS 1863
             S  K+  K   K  S +  D K P  E                          + + + 
Sbjct: 786  KSPVKEEVKSPEKAKSPLKEDAKAPEKE------------------------IPKKEEVK 821

Query: 1864 SLDFDDDDVDLSREKAELRKAKENKESEAKVTSHTELTSNQQSANKTQAIAKQPINRGQP 1923
            S   +++     + K   +KA+E K   A  T  TE   + +     +  A +P    + 
Sbjct: 822  SPVKEEEKPQEVKVKEPPKKAEEEK---APATPKTEEKKDSKKEEAPKKEAPKPKVEEKK 878

Query: 1924 KPILQKQSTFPQSSKDIPDRGAATDEKLQNFAIENTPVCFSHNSSLSSLSDIDQENNNKE 1983
            +P ++K    P+ SK    +  A D+K      +  P          +  ++ ++   KE
Sbjct: 879  EPAVEK----PKESKVEAKKEEAEDKKKVPTPEKEAP----------AKVEVKEDAKPKE 924

Query: 1984 NEPIKETEPPDSQG-EPSKP-QASGYAPKSFHVEDTPVCFSRNSSLSSLSIDSEDDLLQE 2041
               + + EP D++  EPSKP +    AP+    ++           +      +D  L +
Sbjct: 925  KTEVAKKEPDDAKAKEPSKPAEKKEAAPEKKDTKEEKAKKPEEKPKTEAKAKEDDKTLSK 984

Query: 2042 CISSAMPKKKKPSRLKGDNEKHS 2064
                + PK +K  +    ++K S
Sbjct: 985  --EPSKPKAEKAEKSSSTDQKDS 1005



 Score = 54.3 bits (129), Expect = 2e-06
 Identities = 123/629 (19%), Positives = 222/629 (35%), Gaps = 110/629 (17%)

Query: 1121 INQNVSQSLCQEDDYEDDKPTNYSERYSEEEQHEEEER----------PTNYSIKYNEEK 1170
            + +   ++   E+  E+++     E   EEE  EEEE           P   +    +E 
Sbjct: 457  VEEQTEETQVTEEVTEEEEKEAKEEEGKEEEGGEEEEAEGGEEETKSPPAEEAASPEKEA 516

Query: 1171 RHVDQPIDYSLKYATDIPSSQKQ---------SFSFSKSSSGQSSKT--EHMSSSSENTS 1219
            +    P+    K   +  S +K+         S   +KS + + +K+  E  S   E   
Sbjct: 517  K---SPVKEEAKSPAEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPPEAKSPEKEEAK 573

Query: 1220 TPSSNAKRQNQLHPSSAQSRSGQPQKAATCKVSSINQETIQTYCVEDTPICFSRCSSLSS 1279
            +P+     +    P+  +++S    K+   K  S  +E  ++     +P+   +  + S 
Sbjct: 574  SPAEVKSPEKAKSPAKEEAKSPAEAKSPE-KAKSPVKEEAKSPAEAKSPV---KEEAKSP 629

Query: 1280 LSSAEDEIGCNQTTQEADSANTLQIAEIKEKIGTRSAEDPV-----------SEVPAVSQ 1328
                  E   + T +EA S    +  E +E      A+ PV           S V A ++
Sbjct: 630  AEVKSPEKAKSPTKEEAKSPEKAKSPEKEEAKSPEKAKSPVKAEAKSPEKAKSPVKAEAK 689

Query: 1329 HPRTKSSRLQGSSLSSESARHKAVEFSSG---AKSPSKSGAQTP---KSPPEHYVQETPL 1382
             P    S ++  + S E A+    E +     AKSP K  A+TP   KSP +    ++P 
Sbjct: 690  SPEKAKSPVKEEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKTPEKAKSPVKEEA-KSPE 748

Query: 1383 MFSRCTSVSSLD--SFESRSIASSVQSEPCSGMVSGIISP-SDLPDSPGQTMPPSRSKTP 1439
                     +LD  S E+++ A      P         SP  +   SP +   P +    
Sbjct: 749  KAKSPEKAKTLDVKSPEAKTPAKEEARSPADKFPEKAKSPVKEEVKSPEKAKSPLKEDAK 808

Query: 1440 PPP---PQTAQTKREVPKNKAPTAEKRESGPKQAAVNAAVQRVQVLPDADTLLHFATEST 1496
             P    P+  + K  V + + P   K +  PK+    A  ++    P  +       E  
Sbjct: 809  APEKEIPKKEEVKSPVKEEEKPQEVKVKEPPKK----AEEEKAPATPKTEEKKDSKKEEA 864

Query: 1497 PDGFSCSSSLSALSLDEPFIQKDVELRIMPPVQENDNGNETESEQPKESNENQEKEAEKT 1556
            P               +P +++  E  +  P +      + E+E  K+     EKEA   
Sbjct: 865  P----------KKEAPKPKVEEKKEPAVEKPKESKVEAKKEEAED-KKKVPTPEKEAPAK 913

Query: 1557 IDSEKDLLDDSDDDDIEILEECIISAMPTKSSRKAKK-PAQTASKLPPPVARKPSQLPVY 1615
            ++ ++D                   A P + +  AKK P    +K P   A K    P  
Sbjct: 914  VEVKED-------------------AKPKEKTEVAKKEPDDAKAKEPSKPAEKKEAAPEK 954

Query: 1616 KLLPSQNRLQPQKHVSFTPGDDMPRVYCVEGTPINFSTATSLSDLTIESPPNELAAGEGV 1675
            K    +   +P         ++ P+                  D T+   P++  A +  
Sbjct: 955  KDTKEEKAKKP---------EEKPKT----------EAKAKEDDKTLSKEPSKPKAEK-- 993

Query: 1676 RGGAQSGEFEKRDTIPTEGRSTDEAQGGK 1704
                +S   +++D+ P E  + D+A  GK
Sbjct: 994  --AEKSSSTDQKDSKPPEKATEDKAAKGK 1020


>gi|207113160 Treacher Collins-Franceschetti syndrome 1 isoform d
            [Homo sapiens]
          Length = 1488

 Score = 55.8 bits (133), Expect = 6e-07
 Identities = 191/1024 (18%), Positives = 346/1024 (33%), Gaps = 155/1024 (15%)

Query: 1877 EKAELRKAKENKESEAKVTSHTELTSNQQSANKTQAIAKQPINRGQPKPILQKQSTFPQS 1936
            E    RKA+E+   +AK T  ++  S  +S+ + +  A+    +  P+      S     
Sbjct: 58   ELGRKRKAEEDAALQAKKTRVSDPISTSESSEEEEE-AEAETAKATPRLASTNSSVL--- 113

Query: 1937 SKDIPDRGAATDEKLQNFAIENTPVCFSHNSSLSSLSDIDQENNNKENEPIKETEPPDSQ 1996
              D+P   ++  EK +    E      + NS     +     N      P K  EP  + 
Sbjct: 114  GADLP---SSMKEKAK---AETEKAGKTGNSMPHPATGKTVANLLSGKSPRKSAEPSANT 167

Query: 1997 GEPSKPQASGYAPKSFHVEDTP--VCFSRNSSLSSLSIDSEDDLLQECISSAMPKKKKPS 2054
               S+ +  G  P +F     P  V   +  S S  +  S D+   E   S  P + K S
Sbjct: 168  TLVSETEEEGSVP-AFGAAAKPGMVSAGQADSSSEDTSSSSDETDVEGKPSVKPAQVKAS 226

Query: 2055 RLKGDNEKHSPRNMG----GILGEDLTLDLKDIQRPDSEHGLSPDSENFDWKAIQEGANS 2110
             +   + K SP        G +G D+T  +K    P ++    P+ E+   ++ +EG+ S
Sbjct: 227  SV---STKESPARKAAPAPGKVG-DVTPQVKGGALPPAKRAKKPEEES---ESSEEGSES 279

Query: 2111 IVSSLHQAAAAACLSRQASSDSDSILSLKSGISLGSPFHLTPDQEEKPFTSNKGPRILKP 2170
                  + A A   S+  +S+    +   S  + G+P               KG     P
Sbjct: 280  -----EEEAPAGTRSQVKASEKILQVRAASAPAKGTP--------------GKGATPAPP 320

Query: 2171 GEKSTLETKKIESESKGIKGGKKVYKSLITGKVRSNSEISGQMKQPLQANMPSISRGRTM 2230
            G+        + S++K              GK   +SE S +     +   P+    + +
Sbjct: 321  GKAGA-----VASQTKA-------------GKPEEDSESSSEESSDSEEETPA---AKAL 359

Query: 2231 IHIPGVRNSSSSTSPVSKKGPPLKTPASKSPSEGQTATTSPRGAKPSVKSELSPVARQTS 2290
            +       +S  TS V     P K    K  +      T P  AK             + 
Sbjct: 360  LQA----KASGKTSQVGAASAPAKESPRKGAAPAPPGKTGPAVAKAQAGKREEDSQSSSE 415

Query: 2291 QIGGSSKAPSRSGSRDSTPS-RPAQQPLSRPIQSPGRNSISPGRNGISPPNKLSQLPRTS 2349
            +     +AP+++      P  R A  P     +SP + +         P     Q+ +  
Sbjct: 416  ESDSEEEAPAQAKPSGKAPQVRAASAPAK---ESPRKGAAPAPPRKTGPAAAQVQVGKQE 472

Query: 2350 SPSTASTKSSGS----------------GKMSYTSPGRQMSQQNLTKQTGLSKNASSIPR 2393
              S +S++ S S                GK     P   M    L K  G        P 
Sbjct: 473  EDSRSSSEESDSDREALAAMNAAQVKPLGKSPQVKPASTMGMGPLGKGAGPVPPGKVGPA 532

Query: 2394 SESASKGLNQMNNGNGANKKVELSRMSSTKSSGSESDRSERPVLVRQSTFIKEAPSP--- 2450
            + SA  G  + ++ + + +  + S      +     ++S   +L  + T       P   
Sbjct: 533  TPSAQVGKWEEDSESSSEESSDSSDGEVPTAVAPAQEKSLGNILQAKPTSSPAKGPPQKA 592

Query: 2451 -------TLRRKLEESASFESLSPSS----RPASPTRSQAQTPVLSPSLPDMSLSTHSSV 2499
                      + ++ S S E  S S+     PA+ T +QA+  +  P        T+++ 
Sbjct: 593  GPVAVQVKAEKPMDNSESSEESSDSADSEEAPAAMTAAQAKPALKIPQTKACPKKTNTTA 652

Query: 2500 QA--------------GGWRKLPPNLSPTIEYNDGRPAKRHDIARSHSESPSR------- 2538
             A               G    P   SP +     RPA   + + S  ES S        
Sbjct: 653  SAKVAPVRVGTQAPRKAGTATSPAGSSPAVAGGTQRPA---EDSSSSEESDSEEEKTGLA 709

Query: 2539 LPINRSGTWKREHSKHSSSLPRVSTWRRTGSSSSILSASSESSEKAKSEDEKHVNSISGT 2598
            + + ++ +  +     ++S+P V      G++  +   +  +  + K+E ++   S    
Sbjct: 710  VTVGQAKSVGKGLQVKAASVP-VKGSLGQGTAPVLPGKTGPTVTQVKAEKQEDSESSEEE 768

Query: 2599 KQSKENQVSAKGTWRKIKENEFSPTNSTSQTVSSGATNGAESKTL-----IYQMAPAVSK 2653
              S+E   S       +K+ +     + ++  S+  T  A  K +       Q +P+  K
Sbjct: 769  SDSEEAAASPAQVKTSVKKTQAKANPAAARAPSAKGTISAPGKVVTAAAQAKQRSPSKVK 828

Query: 2654 TEDVWVRIEDCPINNPRS----GRSPTGNTPPVIDSVSEKANPNIKDSKDNQAKQNVGNG 2709
                       P+ NP++     R P  + P V  +V+  A       +D+ + +   + 
Sbjct: 829  P----------PVRNPQNSTVLARGP-ASVPSVGKAVATAAQAQTGPEEDSGSSEEESDS 877

Query: 2710 SVPMRTVGLENRLNSFIQVDAPDQKGTEIKPGQNNPVPVSETNESSIVERTPFSSSSSSK 2769
                 T+          Q+ A      E       P P  +T  S+        S SSS+
Sbjct: 878  EEEAETLAQVKPSGKTHQIRAALAPAKESPRKGAAPTPPGKTGPSAAQAGKQDDSGSSSE 937

Query: 2770 HSSPSGTVAARVTPFN--------YNPSPRKSSADSTSARPSQIPTPVNNNTKKRDSKTD 2821
             S   G   A VT            +P+   +   +T A+     TP      +  +++ 
Sbjct: 938  ESDSDGEAPAAVTSAQVIKPPLIFVDPNRSPAGPAATPAQAQAASTPRKARASESTARSS 997

Query: 2822 STES 2825
            S+ES
Sbjct: 998  SSES 1001



 Score = 51.2 bits (121), Expect = 1e-05
 Identities = 153/744 (20%), Positives = 243/744 (32%), Gaps = 124/744 (16%)

Query: 1131 QEDDYEDDKPTNYSERYSEEEQHEEEERPTNYSIKY-------NEEKRHVDQPIDYSLKY 1183
            +ED     K T  S+  S  E  EEEE     + K        N      D P     K 
Sbjct: 66   EEDAALQAKKTRVSDPISTSESSEEEEEAEAETAKATPRLASTNSSVLGADLPSSMKEKA 125

Query: 1184 ATDIPSSQKQSFSFSKSSSGQSSKTEHMSSSSENTSTPSSNAKRQNQLHPSSAQSRSGQP 1243
              +   + K   S    ++G++        S   ++ PS+N    ++     +    G  
Sbjct: 126  KAETEKAGKTGNSMPHPATGKTVANLLSGKSPRKSAEPSANTTLVSETEEEGSVPAFGAA 185

Query: 1244 QKAATCKVSSINQETIQTYCVEDTPICFSRCSSLSSLSSAEDEIGCNQTTQEADSANTLQ 1303
             K         +  +      EDT       SS S  +  E +        +A S +T +
Sbjct: 186  AKPGMVSAGQADSSS------EDT-------SSSSDETDVEGKPSVKPAQVKASSVSTKE 232

Query: 1304 IAEIKEKIGTRSAEDPVSEVPAVSQHPRTKSSRLQGSSLSSESARHKAVEFSSGAKS--- 1360
                K         D   +V   +  P  ++ + +  S SSE       E  +G +S   
Sbjct: 233  SPARKAAPAPGKVGDVTPQVKGGALPPAKRAKKPEEESESSEEGSESEEEAPAGTRSQVK 292

Query: 1361 ------------------PSKSGAQTPKSPPEHYVQET----PLMFSRCTSVSSLDSFES 1398
                              P K     P         +T    P   S  +S  S DS E 
Sbjct: 293  ASEKILQVRAASAPAKGTPGKGATPAPPGKAGAVASQTKAGKPEEDSESSSEESSDSEEE 352

Query: 1399 RSIASSVQSEPCSGMVSGIISPS----------DLPDSPGQTMP---------------- 1432
               A ++     SG  S + + S            P  PG+T P                
Sbjct: 353  TPAAKALLQAKASGKTSQVGAASAPAKESPRKGAAPAPPGKTGPAVAKAQAGKREEDSQS 412

Query: 1433 -PSRSKTPPPPPQTAQTKREVPKNKAPTAEKRESGPKQAA------VNAAVQRVQVLPDA 1485
                S +    P  A+   + P+ +A +A  +ES  K AA         A  +VQV    
Sbjct: 413  SSEESDSEEEAPAQAKPSGKAPQVRAASAPAKESPRKGAAPAPPRKTGPAAAQVQVGKQE 472

Query: 1486 DTLLHFATESTPDGFSCSSSLSALSLDE-------PFIQKDVELRIMP------PVQEND 1532
            +     + ES  D      +L+A++  +       P ++    + + P      PV    
Sbjct: 473  EDSRSSSEESDSD----REALAAMNAAQVKPLGKSPQVKPASTMGMGPLGKGAGPVPPGK 528

Query: 1533 NGNETESEQPKESNENQEKEAEKTIDSEKDLLDDSDDDDIEILEECIISAMPTKSSRKAK 1592
             G  T S Q  +  E+ E  +E++ DS    +  +     E     I+ A PT S   AK
Sbjct: 529  VGPATPSAQVGKWEEDSESSSEESSDSSDGEVPTAVAPAQEKSLGNILQAKPTSS--PAK 586

Query: 1593 KPAQTASKLPPPV-ARKPSQLPVYKLLPSQNRLQPQKHVSFTPGDDMPRVYCVEGTPINF 1651
             P Q A  +   V A KP          S +    +   + T     P +   +      
Sbjct: 587  GPPQKAGPVAVQVKAEKPMDNSESSEESSDSADSEEAPAAMTAAQAKPALKIPQTKACPK 646

Query: 1652 STATSLSDLTIESPPNELAAGEGVRGGAQSGEFEKRDTIPTEGRSTDEAQGGKTSSVTIP 1711
             T T+ S           A    VR G Q+    K  T  +   S+    GG       P
Sbjct: 647  KTNTTAS-----------AKVAPVRVGTQAP--RKAGTATSPAGSSPAVAGGTQR----P 689

Query: 1712 ELDDNKAEEGDILAECINSAMPKGKSHKPFRVKKIMDQVQQASASSSAPNKNQLDGKKKK 1771
              D + +EE D   E    A+  G++      K +   +Q  +A  S P K  L G+   
Sbjct: 690  AEDSSSSEESDSEEEKTGLAVTVGQA------KSVGKGLQVKAA--SVPVKGSL-GQGTA 740

Query: 1772 PTSPVKPIPQNTEYRTRVRKNADS 1795
            P  P K  P  T+ +   +++++S
Sbjct: 741  PVLPGKTGPTVTQVKAEKQEDSES 764



 Score = 50.8 bits (120), Expect = 2e-05
 Identities = 154/804 (19%), Positives = 274/804 (34%), Gaps = 109/804 (13%)

Query: 1202 SGQSSKTEHMSSSSENTSTPSSNAKRQNQLHPSSAQSRSGQPQKAATCKVSSINQETIQT 1261
            S Q  K E  S SS   S+ SS+ +    + P+  +S     Q   T   +    +    
Sbjct: 535  SAQVGKWEEDSESSSEESSDSSDGEVPTAVAPAQEKSLGNILQAKPTSSPAKGPPQKAGP 594

Query: 1262 YCVE---DTPICFSRCSSLSSLSSAEDEIGCNQTTQEADSANTLQIAEIKEKIGTRSAED 1318
              V+   + P+  S  S  SS S+  +E     T  +A  A  +   +   K    +A  
Sbjct: 595  VAVQVKAEKPMDNSESSEESSDSADSEEAPAAMTAAQAKPALKIPQTKACPKKTNTTASA 654

Query: 1319 PVSEVPAVSQHPRTKSSRLQGSSLSSESARHKAVEFSSGAKSPSKSGAQTPKSPPEHYVQ 1378
             V+ V   +Q PR      +  + +S +    AV  + G + P++  + + +S  E   +
Sbjct: 655  KVAPVRVGTQAPR------KAGTATSPAGSSPAV--AGGTQRPAEDSSSSEESDSEE--E 704

Query: 1379 ETPLMFSRCTSVSSLDSFESRSIASSVQSEPCSGMVSGIISPSDLPDSPGQTMPPSRSKT 1438
            +T L         ++   +++S+   +Q +  S  V G +     P  P         KT
Sbjct: 705  KTGL---------AVTVGQAKSVGKGLQVKAASVPVKGSLGQGTAPVLP--------GKT 747

Query: 1439 PPPPPQTAQTKREVPKNKAPTAEKRESGPKQAAVNAAVQRVQVLPDADTLLHFATESTPD 1498
             P   Q    K+E  ++    ++  E+    A V  +V++ Q   +       A    P 
Sbjct: 748  GPTVTQVKAEKQEDSESSEEESDSEEAAASPAQVKTSVKKTQAKANP------AAARAPS 801

Query: 1499 GFSCSSSLSALSLDEPFIQKDVELRIMPPVQENDNGNETESEQPKESNENQ--EKEAEKT 1556
                 S+   +       ++    ++ PPV+   N            +  +     A+  
Sbjct: 802  AKGTISAPGKVVTAAAQAKQRSPSKVKPPVRNPQNSTVLARGPASVPSVGKAVATAAQAQ 861

Query: 1557 IDSEKDLLDDSDDDDIEILEECIISAMPTKSSRKAKKPAQTASKLP-------PPVARKP 1609
               E+D     ++ D E   E +    P+  + + +     A + P       PP    P
Sbjct: 862  TGPEEDSGSSEEESDSEEEAETLAQVKPSGKTHQIRAALAPAKESPRKGAAPTPPGKTGP 921

Query: 1610 SQLPVYKLLPSQNRLQPQKHVSFTPGD------DMPRVYCVEGTPINFSTATSLSDLTIE 1663
            S     K   S +  +        P          P +  V+        A + +     
Sbjct: 922  SAAQAGKQDDSGSSSEESDSDGEAPAAVTSAQVIKPPLIFVDPNRSPAGPAATPAQAQAA 981

Query: 1664 SPPNELAAGEGVRGGAQSGEFEKRDTIP-----TEGRSTD--------------EAQGGK 1704
            S P +  A E     + S E E  D IP     T G  T+               +  G 
Sbjct: 982  STPRKARASEST-ARSSSSESEDEDVIPATQCLTPGIRTNVVTMPTAHPRIAPKASMAGA 1040

Query: 1705 TSSVTIPELDDNKAEEGDILAECINSAMPKGKSHKPFRVKKIMDQVQQASASSSAPNKNQ 1764
            +SS     + D K +EG            K  +  P     +    Q+AS +     + Q
Sbjct: 1041 SSSKESSRISDGKKQEGP-----ATQVSKKNPASLPLTQAALKVLAQKASEAQPPVARTQ 1095

Query: 1765 LDGKKKKPTSPVKPIPQNTEYRTRVRKNADSKNNLNAERVFSDNKDSKKQNLKNNSKVFN 1824
                     S V  +P  +   T V+  A   N L   ++    + +K     ++S+  +
Sbjct: 1096 ---PSSGVDSAVGTLPATSPQSTSVQ--AKGTNKLRKPKLPEVQQATKAPESSDDSEDSS 1150

Query: 1825 DKLPNNEDRVRGSFAFDSPHHYTPIEGTPYCFSRNDSL---SSLDFDDDDV--------- 1872
            D    +E+   G     S H   P   TP   SR ++L   ++ +  +DDV         
Sbjct: 1151 DSSSGSEEDGEGPQGAKSAHTLGP---TP---SRTETLVEETAAESSEDDVVAPSQSLLS 1204

Query: 1873 -----DLSREKAELRKAKENKESEAKVTSHTELTSNQQSANKTQAIAKQPINRGQPKPIL 1927
                  L+   ++  KA    +S   V+S   L +      K +A  +Q      PK   
Sbjct: 1205 GYMTPGLTPANSQASKATPKLDSSPSVSS--TLAAKDDPDGKQEAKPQQAAGMLSPKTGG 1262

Query: 1928 QK--QSTFPQSSKDIPDRGAATDE 1949
            ++    T PQ S+  P +GA   +
Sbjct: 1263 KEAASGTTPQKSRK-PKKGAGNPQ 1285



 Score = 37.4 bits (85), Expect = 0.21
 Identities = 74/346 (21%), Positives = 118/346 (34%), Gaps = 61/346 (17%)

Query: 2540 PINRSGTWKREHSKHSSSLPRVSTWRRTGSSSSILSASSESS--EKAKSEDEKH------ 2591
            PI+ S + + E    + +    +T R   ++SS+L A   SS  EKAK+E EK       
Sbjct: 81   PISTSESSEEEEEAEAETAK--ATPRLASTNSSVLGADLPSSMKEKAKAETEKAGKTGNS 138

Query: 2592 ----------VNSISGTKQSKENQVSAKGTWRKIKENEFSPTN----------STSQTVS 2631
                       N +SG    K  + SA  T     E E S             S  Q  S
Sbjct: 139  MPHPATGKTVANLLSGKSPRKSAEPSANTTLVSETEEEGSVPAFGAAAKPGMVSAGQADS 198

Query: 2632 SGATNGAESKTLIYQMAPAV--SKTEDVWVRIEDCPINNPRSGRSPTGNTPPVIDSVSEK 2689
            S     + S     +  P+V  ++ +   V  ++ P           G+  P +   +  
Sbjct: 199  SSEDTSSSSDETDVEGKPSVKPAQVKASSVSTKESPARKAAPAPGKVGDVTPQVKGGALP 258

Query: 2690 ANPNIKDSKDNQAKQNVGNGSVPMRTVGLENRLNS---FIQVDA--------PDQKGTEI 2738
                 K  ++       G+ S      G  +++ +    +QV A        P +  T  
Sbjct: 259  PAKRAKKPEEESESSEEGSESEEEAPAGTRSQVKASEKILQVRAASAPAKGTPGKGATPA 318

Query: 2739 KPGQNNPVPVSETNESSIVERTPFSSSSSS---------------KHSSPSGTVAARVTP 2783
             PG+   V  S+T      E +  SS  SS               K S  +  V A   P
Sbjct: 319  PPGKAGAV-ASQTKAGKPEEDSESSSEESSDSEEETPAAKALLQAKASGKTSQVGAASAP 377

Query: 2784 FNYNPSPRKSSADSTSARPSQIPTPVNNNTKKRDSKTDSTESSGTQ 2829
                 SPRK +A +   +            ++ DS++ S ES   +
Sbjct: 378  AK--ESPRKGAAPAPPGKTGPAVAKAQAGKREEDSQSSSEESDSEE 421



 Score = 37.4 bits (85), Expect = 0.21
 Identities = 54/221 (24%), Positives = 89/221 (40%), Gaps = 24/221 (10%)

Query: 2235 GVRNSSSSTSPVS----KKG---PPLKTPASKSPSE----GQTATTSPRGAKPSVKSELS 2283
            G + ++S T+P      KKG   P   T A +S       GQ    +    + SV   L+
Sbjct: 1261 GGKEAASGTTPQKSRKPKKGAGNPQASTLALQSNITQCLLGQPWPLNEAQVQASVVKVLT 1320

Query: 2284 PVARQT-SQIGGSSKAPSRSGSRDSTPSRPAQQPLSRPIQSPGRNSISPGRNGISP--PN 2340
             +  Q   ++  ++K  SR G           QP +R  +S  +  +  G  G +   P 
Sbjct: 1321 ELLEQERKKVVDTTKESSRKGWESRKRKLSGDQPAARTPRSKKKKKLGAGEGGEASVSPE 1380

Query: 2341 KLSQLPRTSSPSTASTKSSGS-----GKMSYTSPG-RQMSQQNLTKQTGLSKNAS-SIPR 2393
            K S    TS       K+SG      GK S  S G +   ++ L K  G  +    S P+
Sbjct: 1381 KTST---TSKGKAKRDKASGDVKEKKGKGSLGSQGAKDEPEEELQKGMGTVEGGDQSNPK 1437

Query: 2394 SESASKGLNQMNNGNGANKKVELSRMSSTKSSGSESDRSER 2434
            S+   K  ++        +K + ++ +STK S S S + ++
Sbjct: 1438 SKKEKKKSDKRKKDKEKKEKKKKAKKASTKDSESPSQKKKK 1478


>gi|120953251 neuron navigator 3 [Homo sapiens]
          Length = 2363

 Score = 55.8 bits (133), Expect = 6e-07
 Identities = 144/604 (23%), Positives = 237/604 (39%), Gaps = 115/604 (19%)

Query: 2046 AMPKKKKPSRLKGDNEKHSPRNMGGILGEDLTLDLKDIQRPDSEHGLSPDSENFDWKAIQ 2105
            A   +K  + LKG + + SP + G   G++        ++P S  G S  + +F +K   
Sbjct: 1019 AKASEKGKAPLKGSSLQRSPSDAGKSSGDEG-------KKPPSGIGRSTATSSFGFKK-- 1069

Query: 2106 EGANSIVSSLHQAAAAACLSRQASSDSDSILSLKSGISLGSPFHLTPDQEEKPFTSNKGP 2165
                   S +  +A         +S S ++  +    ++G   +    +     + N+  
Sbjct: 1070 ------PSGVGSSAMITSSGATITSGSATLGKIPKSAAIGGKSN-AGRKTSLDGSQNQDD 1122

Query: 2166 RILKPGEKSTLETKKIESESK----GI--KGGKKVYKSLI------------TGKVRSNS 2207
             +L    K+TL+ + +   SK    GI  +GG +   S I            T K+R  +
Sbjct: 1123 VVLHVSSKTTLQYRSLPRPSKSSTSGIPGRGGHRSSTSSIDSNVSSKSAGATTSKLREPT 1182

Query: 2208 EISGQMKQPLQANMP-------SISRGRTMIHIPGVRNSSSSTSPVSKKGPPLKTPASKS 2260
            +I      P+  N         ++S   ++      ++S +S S    +G  L+ P SK 
Sbjct: 1183 KIGSGRSSPVTVNQTDKEKEKVAVSDSESVSLSGSPKSSPTSASACGAQG--LRQPGSKY 1240

Query: 2261 PSEGQTATTSPRGAKPSVKSELSPVARQTSQIGGSSKAPSRSGSRDSTPSRPAQQPLSRP 2320
            P           GAK   KS  +P    T  +  SS  PS S    +T +R  Q  L  P
Sbjct: 1241 PDIASPTFRRLFGAKAGGKSASAP---NTEGVKSSSVMPSPS----TTLAR--QGSLESP 1291

Query: 2321 IQSPGRNSISPGRNGISPP--NKLSQLPR---------TSSPSTASTKSSG----SGKMS 2365
                G    + G +G S P  NK S L            SSP++  + +SG    +  MS
Sbjct: 1292 SSGTGSMGSAGGLSGSSSPLFNKPSDLTTDVISLSHSLASSPASVHSFTSGGLVWAANMS 1351

Query: 2366 YTSPGRQMSQQNLTKQTGLSKNASSIPRSESASKGLNQMNNGNGANKKVELSRMSSTKSS 2425
             +S G +    +    T L  ++ SI    S    L+ +  G    + + L R  S +S+
Sbjct: 1352 SSSAGSK-DTPSYQSMTSLHTSSESIDLPLSHHGSLSGLTTGTHEVQSL-LMRTGSVRST 1409

Query: 2426 GSESDRSERPVLVRQSTFIKEAPSPTLRRKLEESASFESLSPSSRPASPTRSQAQTPVLS 2485
             SES + +R  L ++        +P+ R+  +E       S S+     T +  Q+P++S
Sbjct: 1410 LSESMQLDRNTLPKKGL----RYTPSSRQANQEEGKEWLRSHSTGGLQDTGN--QSPLVS 1463

Query: 2486 PSLPDMSLSTHSSVQAGGWR----KLPPNLS------PTIEYNDGRPAKRHDI------- 2528
            P       S  SS  AG +       P NLS      P++  ++  PA+           
Sbjct: 1464 P-------SAMSSSAAGKYHFSNLVSPTNLSQFNLPGPSMMRSNSIPAQDSSFDLYDDSQ 1516

Query: 2529 ----ARSHSESPSRLPINRSGTWKREHSK-HSSSLPRVSTWRRTGSSSSILSASSESSEK 2583
                A S  E P    I+ SG+++    + H SSL  VS      S+SS+ S    + EK
Sbjct: 1517 LCGSATSLEERPR--AISHSGSFRDSMEEVHGSSLSLVS------STSSLYST---AEEK 1565

Query: 2584 AKSE 2587
            A SE
Sbjct: 1566 AHSE 1569



 Score = 40.4 bits (93), Expect = 0.025
 Identities = 134/641 (20%), Positives = 238/641 (37%), Gaps = 113/641 (17%)

Query: 2250 GPPLKTPASKSPSE----GQTATTSPRGAKPSVKSELSPVARQTSQIGGSSKAPSRSGSR 2305
            G   KT +S  P +    GQ A+ S        +   +     + Q  G+S   +   + 
Sbjct: 958  GGKWKTVSSGLPEDPEKAGQKASLSVSQTGSWRRGMSAQGGAPSRQKAGTSALKTPGKTD 1017

Query: 2306 DSTPSRPAQQPL--SRPIQSPGRNSISPGRNGISPPNKLSQLPRTSS------------- 2350
            D+  S   + PL  S   +SP     S G  G  PP+ + +   TSS             
Sbjct: 1018 DAKASEKGKAPLKGSSLQRSPSDAGKSSGDEGKKPPSGIGRSTATSSFGFKKPSGVGSSA 1077

Query: 2351 --PSTASTKSSGSGKM----------SYTSPGRQMSQQNLTKQTGLSKNAS--------S 2390
               S+ +T +SGS  +            ++ GR+ S      Q  +  + S        S
Sbjct: 1078 MITSSGATITSGSATLGKIPKSAAIGGKSNAGRKTSLDGSQNQDDVVLHVSSKTTLQYRS 1137

Query: 2391 IPR-SESASKGLNQMNNGNGANKKVELSRMSSTKSSGSESDRSERPVLVRQSTFIKEAPS 2449
            +PR S+S++ G+     G   +    +    S+KS+G+ + +   P  +          +
Sbjct: 1138 LPRPSKSSTSGI--PGRGGHRSSTSSIDSNVSSKSAGATTSKLREPTKIGSGRSSPVTVN 1195

Query: 2450 PTLRRKLEESAS-FESLSPSSRP-ASPTRSQA-------QTPVLSPSLPDMSLSTHSSVQ 2500
             T + K + + S  ES+S S  P +SPT + A       Q     P +   +       +
Sbjct: 1196 QTDKEKEKVAVSDSESVSLSGSPKSSPTSASACGAQGLRQPGSKYPDIASPTFRRLFGAK 1255

Query: 2501 AGGWRKLPPNLSPTIEYNDGRPAKRHDIARSHS-ESPSRLPINRSGTWKREHSKHSSSLP 2559
            AGG     PN +  ++ +   P+    +AR  S ESPS      SGT             
Sbjct: 1256 AGGKSASAPN-TEGVKSSSVMPSPSTTLARQGSLESPS------SGTGSMG--------- 1299

Query: 2560 RVSTWRRTGSSSSILSASSESSEKAKSEDEKHVNSISGTKQSKENQVSAKGTWRKIKENE 2619
              S    +GSSS + +  S+ +    S      +S++ +  S  +  S    W       
Sbjct: 1300 --SAGGLSGSSSPLFNKPSDLTTDVISLS----HSLASSPASVHSFTSGGLVW------- 1346

Query: 2620 FSPTNSTSQTVSSGATNGAESKTLIYQMAPAVSKTEDVWVRIEDCPINNPRSGRSPTGNT 2679
                N +S +  S  T   +S T ++  + ++           D P+++  S    T  T
Sbjct: 1347 --AANMSSSSAGSKDTPSYQSMTSLHTSSESI-----------DLPLSHHGSLSGLTTGT 1393

Query: 2680 PPVIDSVSEKANPNIKDSKDNQAKQNVGNGSVPMRTVGLENRLNSFIQVDAPDQKGTEIK 2739
              V   +    +     S+  Q  +N    ++P +  GL    +S     A  ++G E  
Sbjct: 1394 HEVQSLLMRTGSVRSTLSESMQLDRN----TLPKK--GLRYTPSS---RQANQEEGKEWL 1444

Query: 2740 PGQNNPVPVSETNESSIVERTPFSSSSSSKHSSPSGTVAARVTPFNYNPSPRKSSADSTS 2799
               +        N+S +V  +  SSS++ K+   +      ++ FN  P P       + 
Sbjct: 1445 RSHSTGGLQDTGNQSPLVSPSAMSSSAAGKYHFSNLVSPTNLSQFNL-PGP-------SM 1496

Query: 2800 ARPSQIPTPVNNNTKKRDSKTDSTESSGTQSPK--RHSGSY 2838
             R + IP   ++     DS+   + +S  + P+   HSGS+
Sbjct: 1497 MRSNSIPAQDSSFDLYDDSQLCGSATSLEERPRAISHSGSF 1537



 Score = 39.3 bits (90), Expect = 0.056
 Identities = 193/1032 (18%), Positives = 360/1032 (34%), Gaps = 139/1032 (13%)

Query: 1879 AELRKAKENKESEAKVTSHTELTSNQQSANKTQAIAKQPINRGQPKPILQKQSTFPQSSK 1938
            +E  +AK  ++ ++ + +     SN      +Q   K+P     P       S  P +  
Sbjct: 210  SEASQAKTQQDMQSSLAARYATQSNHSGIATSQ---KKPTRLPGP-------SRVPAAGS 259

Query: 1939 DIPDRGAAT-DEKLQNFAI--ENTPVCFSH-NSSLSSLSDIDQENNNKENEPIKETEPPD 1994
                +GA+  + + Q+F    +N P  +++ N   SS         N   +P      P 
Sbjct: 260  SSKVQGASNLNRRSQSFNSIDKNKPPNYANGNEKDSSKGPQSSSGVNGNVQPPSTAGQPP 319

Query: 1995 SQGEPSKPQASGYAPKSFHVED--TPVCFSRNSSLSSLSIDSEDDLLQECISSAMPKKKK 2052
            +   PS   +  +  KS +V+   T    +   S ++ S     D L+  +S  +     
Sbjct: 320  ASAIPSPSASKPWRSKSMNVKHSATSTMLTVKQSSTATSPTPSSDRLKPPVSEGV----- 374

Query: 2053 PSRLKGDNEKHSPRNMGGILGEDLTLDLKDIQRPDSEHGLSP-----DSENFDWKAIQEG 2107
                     K +P     +L +   ++ +   RP       P     D + F      EG
Sbjct: 375  ---------KTAPSGQKSMLEKFKLVNARTALRPPQPPSSGPSDGGKDDDAFSESGEMEG 425

Query: 2108 ANSIVSSLHQAAAAACLSRQASSDSDSILSLKSGISLGSPFHLTPDQEEKPFTSNKGPRI 2167
             NS ++S     ++  +S + +       +L +  SL  P        +K     + P  
Sbjct: 426  FNSGLNSGGSTNSSPKVSPKLAPPKAGSKNLSNKKSLLQPKEKEEKNRDKNKVCTEKPVK 485

Query: 2168 LKPGEKSTLETKKIESESKGIKGGKKVYKSLITGKVRSNSEISGQMKQPLQANMPSISRG 2227
             +  + + +  KK    +  I  G K   +     + S+S I         + +P++ + 
Sbjct: 486  EEKDQVTEMAPKKTSKIASLIPKGSKTTAAKKESLIPSSSGIPKP-----GSKVPTVKQT 540

Query: 2228 RTMIHIPGVRNSSSSTSPVSKKGPPLKTPASKSPSEGQTATTSPRGAKPSVKSELSPVAR 2287
             +    PG   S  S    + KG P ++ +     E  +A++ P   +     + SP   
Sbjct: 541  IS----PGSTASKESEKFRTTKGSPSQSLSKPITMEKASASSCPAPLEGREAGQASP--- 593

Query: 2288 QTSQIGGSSKAPSRSGSRDSTPSRPAQQPLSRPIQSPGRNSISPGRNGISPPNKLSQLPR 2347
                  GS        S  ST +   Q P  +    P   +++P        N+ + LP 
Sbjct: 594  -----SGSCTMTVAQSSGQSTGNGAVQLPQQQQHSHPNTATVAPFIYRAHSENEGTALPS 648

Query: 2348 TSSPSTASTKSSGSGKMSYTSPGRQ-----MSQQNLTKQTGLSKNASSIPRS-ESASKGL 2401
              S  T+ TK      +SY+   +Q       +   T++    KN + + ++ E     L
Sbjct: 649  ADS-CTSPTKMD----LSYSKTAKQCLEEISGEDPETRRMRTVKNIADLRQNLEETMSSL 703

Query: 2402 NQMNNGNGANKKVELSRMSSTKSSGSESDRSERPV-----LVRQSTFIKEAPSPTLRRKL 2456
                  +   +    S +++  +  +  + + RP      L +    ++   +P+L    
Sbjct: 704  RGTQISHSTLETTFDSTVTTEVNGRTIPNLTSRPTPMTWRLGQACPRLQAGDAPSLGAGY 763

Query: 2457 EESAS--FESLSPSS-RPASPTRSQAQTPVLSPSLPDMS------LSTHSSVQAGGWRKL 2507
              S +  F    PS     +P R  A + + + S  DMS      L   S V  GG+   
Sbjct: 764  PRSGTSRFIHTDPSRFMYTTPLRRAAVSRLGNMSQIDMSEKASSDLDMSSEVDVGGYMSD 823

Query: 2508 PPNLSPTIEYNDGRPAKRHDIARS-HSESPSRLPINRSGTWKREHSKHSSSLPRVSTWRR 2566
               L  ++  +D       D   + ++ S +R+P   +     +   H  ++    +W  
Sbjct: 824  GDILGKSLRTDDINSGYMTDGGLNLYTRSLNRIPDTATSRDIIQRGVHDVTVD-ADSW-- 880

Query: 2567 TGSSSSILSASSESSEKAKSEDEKHVNSISG-------------TKQSKENQVSAKGTW- 2612
               SSS+ S  S++ +   ++D    +S+S               +   E + +   TW 
Sbjct: 881  -DDSSSVSSGLSDTLDNISTDDLNTTSSVSSYSNITVPSRKNTQLRTDSEKRSTTDETWD 939

Query: 2613 ----RKIKENEFSPTNSTS---QTVSSGATNGAESKTLIYQMAPAVSKTEDVWVRIEDCP 2665
                 K  E +F          +TVSSG     E      + + +VS+T   W R     
Sbjct: 940  SPEELKKPEEDFDSHGDAGGKWKTVSSGLPEDPEKAG--QKASLSVSQTGS-WRRGMSAQ 996

Query: 2666 INNPRSGRSPTG--NTPPVID--SVSEKANPNIKDSKDNQAKQNVG-----NGSVPMRTV 2716
               P   ++ T    TP   D    SEK    +K S   ++  + G      G  P   +
Sbjct: 997  GGAPSRQKAGTSALKTPGKTDDAKASEKGKAPLKGSSLQRSPSDAGKSSGDEGKKPPSGI 1056

Query: 2717 GLENRLNSFIQVDAPDQKGTEIKPGQNNPVPVSETNESSIVERTPFSSSSSSKHSSPSGT 2776
            G     +SF     P   G+      +     + T+ S+ + + P S++   K ++   T
Sbjct: 1057 GRSTATSSF-GFKKPSGVGSSAMITSSG---ATITSGSATLGKIPKSAAIGGKSNAGRKT 1112

Query: 2777 --------------VAARVT-PFNYNPSPRKSSADSTSARPSQIPTPVNNNTKKRDSKTD 2821
                          V+++ T  +   P P KSS      R         ++T   DS   
Sbjct: 1113 SLDGSQNQDDVVLHVSSKTTLQYRSLPRPSKSSTSGIPGRGGH-----RSSTSSIDSNVS 1167

Query: 2822 STESSGTQSPKR 2833
            S  +  T S  R
Sbjct: 1168 SKSAGATTSKLR 1179



 Score = 32.0 bits (71), Expect = 8.9
 Identities = 54/243 (22%), Positives = 94/243 (38%), Gaps = 24/243 (9%)

Query: 55   IEDEAMASS--GQIDLLERLKELNLDSSNFPGVKLRSKMSLRSYGSREGSVSSRSGECSP 112
            +   AM+SS  G+      +   NL   N PG  +    S+ +  S            S 
Sbjct: 1462 VSPSAMSSSAAGKYHFSNLVSPTNLSQFNLPGPSMMRSNSIPAQDSSFDLYDDSQLCGSA 1521

Query: 113  VPMGSFPRRGFVNGSRESTGYLEELEKERSLLLADLDK--EEKEKDWYYAQLQNLTKRID 170
              +   PR    +GS   +  +EE+      L++         E+  +  Q+  L + + 
Sbjct: 1522 TSLEERPRAISHSGSFRDS--MEEVHGSSLSLVSSTSSLYSTAEEKAHSEQIHKLRREL- 1578

Query: 171  SLPLTENFSLQTDMTRRQLEYEARQIRVAMEEQLGTCQDMEKRAQRRIARIQQIEKDILR 230
             +   E  +  T     QL   A  +  A E+ LG   +M  R Q      +Q E +++ 
Sbjct: 1579 -VASQEKVATLTS----QLSANAHLV-AAFEKSLG---NMTGRLQSLTMTAEQKESELIE 1629

Query: 231  IRQ---LLQSQATEAERSSQNKHETGSHDAE-----RQNEGQGVGEINMATSGNGQGSTT 282
            +R+   +L++Q + A+ + Q       H  +     RQ+  + V  IN ATS +  GS  
Sbjct: 1630 LRETIEMLKAQNSAAQAAIQGALNGPDHPPKDLRIRRQHSSESVSSINSATSHSSIGSGN 1689

Query: 283  RMD 285
              D
Sbjct: 1690 DAD 1692


>gi|83367077 mucin 16 [Homo sapiens]
          Length = 14507

 Score = 55.5 bits (132), Expect = 8e-07
 Identities = 352/1860 (18%), Positives = 641/1860 (34%), Gaps = 318/1860 (17%)

Query: 1205 SSKTEHMSSSSENTSTPSSNAKRQNQLHPSS-------------AQSRSGQPQKAATCKV 1251
            +S   ++ S+S    T S + K   +++PS+              +S S  P  +   KV
Sbjct: 6560 ASLPPNLGSTSHKIPTTSEDIKDTEKMYPSTNIAVTNVGTTTSEKESYSSVPAYSEPPKV 6619

Query: 1252 SSINQETIQTYCVEDTPICFSRCSSLSSLSSAEDEI------GCNQTTQEADSANTLQIA 1305
            +S     + ++ + DT +  S   S S ++  E E       G   T+   D   + + +
Sbjct: 6620 TS---PMVTSFNIRDTIVSTSMPGS-SEITRIEMESTFSLAHGLKGTSTSQDPIVSTEKS 6675

Query: 1306 EIKEKIGTRSAEDPVSEVPAVSQHPRTKSSRLQGSSLSSESARHK-----AVEFSSGAKS 1360
             +  K+ T + E   +EV +      ++ + + G   S+ES         ++  S G   
Sbjct: 6676 AVLHKLTTGATETSRTEVAS------SRRTSIPGPDHSTESPDISTEVIPSLPISLGITE 6729

Query: 1361 PSKSGAQTPKSPP------EHYVQETPLMFSRC-TSVSSLDSFESRSIASSVQSEPCSGM 1413
             S     T   PP        +  +TP   SR  T   +   F    + + +  +P   +
Sbjct: 6730 SSNMTIITRTGPPLGSTSQGTFTLDTPTTSSRAGTHSMATQEFPHSEMTTVMNKDP--EI 6787

Query: 1414 VSGIISPS--------DLPDSPGQTMPPSRSKTP------PPP------PQTAQTKREVP 1453
            +S  I PS         L  SP  T PP  S  P      P P      P    T   + 
Sbjct: 6788 LSWTIPPSIEKTSFSSSLMPSPAMTSPPVSSTLPKTIHTTPSPMTSLLTPSLVMTTDTLG 6847

Query: 1454 KNKAPTAEKRESGPKQAAVNAAVQRVQVLPDADTLLHFATESTPDGFSCSSSLSALSLDE 1513
             +  PT     S P  ++ +  +        A   +H +T +       +SS    S   
Sbjct: 6848 TSPEPTTS---SPPNLSSTSHEILTTDEDTTAIEAMHPSTSTAATNVETTSSGHG-SQSS 6903

Query: 1514 PFIQKDVELRIMPPVQENDNGNETESEQPKESNENQEKEAEKTIDSEKDLLDDSDDDDIE 1573
                 +      P    +  G+ T S     S+E  + + E T      L + S   +  
Sbjct: 6904 VLADSEKTKATAPMDTTSTMGHTTVSTSMSVSSETTKIKRESTYSLTPGLRETSISQNAS 6963

Query: 1574 ILEEC--IISAMPTKSSRKAKKPAQTAS---KLPPPVARKPSQLPVYKLLPSQNRLQPQK 1628
               +   ++S +PT ++ +  +   T+S    +P P     SQ  V   + ++   +   
Sbjct: 6964 FSTDTSIVLSEVPTGTTAEVSRTEVTSSGRTSIPGP-----SQSTVLPEISTRTMTRLFA 7018

Query: 1629 HVSFTPGDDMPRVYCVEGTPINFSTATSLSDLTIESPPNELAAGEGVRGGAQSGEFEKRD 1688
              + T   +M        T    S +TS   LT+++   +  A                 
Sbjct: 7019 SPTMTESAEM-----TIPTQTGPSGSTSQDTLTLDTSTTKSQA---------KTHSTLTQ 7064

Query: 1689 TIPTEGRSTDEAQG-GKTSSVTIPELDDNKAEEGDILAECINSAMPKGKSHKPFRVKKIM 1747
              P    +T  ++G G  S  + P L+ N +    +L+    ++ P   S  P  +    
Sbjct: 7065 RFPHSEMTTLMSRGPGDMSWQSSPSLE-NPSSLPSLLSLPATTSPPPISSTLPVTISSSP 7123

Query: 1748 DQVQQASASSSAPNKNQLDGKKKKPTSPVKPIPQNTEYRTRVRKNADSKNNLN-AERVFS 1806
              V     SS     + L    +  TS    +   ++ R    K+  +   ++ +    +
Sbjct: 7124 LPVTSLLTSSPVTTTDMLHTSPELVTSSPPKLSHTSDERLTTGKDTTNTEAVHPSTNTAA 7183

Query: 1807 DNKDSKKQNLKNNSKVFNDKLPNNEDRVRGSFAFDSPHHYTPIEGTPYCFS----RNDSL 1862
             N +      ++ S    D            F   +    T    TP+       + +S+
Sbjct: 7184 SNVEIPSSGHESPSSALADS--ETSKATSPMFITSTQEDTTVAISTPHFLETSRIQKESI 7241

Query: 1863 SSLDFDDDDVDLSRE------------KAELRKAKENKESEAKVTSHTELTSNQQSANKT 1910
            SSL     +   S E            +  +    E   +E   +S T ++ + +S    
Sbjct: 7242 SSLSPKLRETGSSVETSSAIETSAVLSEVSIGATTEISRTEVTSSSRTSISGSAESTMLP 7301

Query: 1911 QAIAKQPINRGQPKPILQKQSTFPQSSKDIPDRGAATDEKLQNFAIENTP-VCFSHNSSL 1969
            +    + I +    PIL + S     ++  P    +T E         TP +  +H++  
Sbjct: 7302 EISTTRKIIKFPTSPILAESSEMTIKTQTSPP--GSTSESTFTLDTSTTPSLVITHSTMT 7359

Query: 1970 SSL--SDIDQENNNKENE-------PIKETEPPDSQ----GEPSKPQASGYAPKSFHVED 2016
              L  S+I    +    +       P++ET PP SQ       S    S   P S H   
Sbjct: 7360 QRLPHSEITTLVSRGAGDVPRPSSLPVEETSPPSSQLSLSAMISPSPVSSTLPASSHSSS 7419

Query: 2017 TPVC---------------------FSRNSSLSSLSID--------SEDDLLQECISSAM 2047
              V                       S   SLSS S++        ++ + +    ++A+
Sbjct: 7420 ASVTSLLTPGQVKTTEVLDASAEPETSSPPSLSSTSVEILATSEVTTDTEKIHPFSNTAV 7479

Query: 2048 PK-------KKKPSRLKGDNEKHSPRNMGG---ILGE----DLTLDLKDIQRPDSEHGLS 2093
             K        + PS +  D+E     +  G   I+G+     LT  L + ++  SE   S
Sbjct: 7480 TKVGTSSSGHESPSSVLPDSETTKATSAMGTISIMGDTSVSTLTPALSNTRKIQSEPASS 7539

Query: 2094 -----PDSENFDWKAIQEGANSIVSSLHQAAAAACLSRQASSDSDSILS------LKSGI 2142
                  ++   +  ++   AN+++S +   A       +A S S + +S      +   I
Sbjct: 7540 LTTRLRETSTSEETSLATEANTVLSKVSTGATTEVSRTEAISFSRTSMSGPEQSTMSQDI 7599

Query: 2143 SLG-----SPFHLTPDQEEKPFTSNKGPRILKPGEKSTLETKKIESESKGIKGGKKVYKS 2197
            S+G     S   +  +  +   T+  GP       +STLE+  +   +       + +  
Sbjct: 7600 SIGTIPRISASSVLTESAKMTITTQTGP------SESTLES-TLNLNTATTPSWVETHSI 7652

Query: 2198 LITG-----KVRSNSEISGQMKQPLQANMPSISRGRTMIHIPGVRNSSSSTSPVSKKGPP 2252
            +I G        S     G +  P    +   S   + + +P V +    ++      PP
Sbjct: 7653 VIQGFPHPEMTTSMGRGPGGVSWPSPPFVKETSPPSSPLSLPAVTSPHPVSTTFLAHIPP 7712

Query: 2253 LKTPASKSPSEGQTATTSPRGAK----PSVKSELSPVARQ----------------TSQI 2292
               P +   + G   TT   G       S  S LS  + +                ++  
Sbjct: 7713 SPLPVTSLLTSGPATTTDILGTSTEPGTSSSSSLSTTSHERLTTYKDTAHTEAVHPSTNT 7772

Query: 2293 GGSSKAPSRSGSR-------DSTP--------------SRPAQQPLSRPIQSPGRNSISP 2331
            GG++ A + SG +       DS+P              S PA    +R IQ+   +S++P
Sbjct: 7773 GGTNVATTSSGYKSQSSVLADSSPMCTTSTMGDTSVLTSTPAFLE-TRRIQTELASSLTP 7831

Query: 2332 ------GRNGISPPNKLSQLPRTSSPSTASTKSSGSGKMSYTSPGRQMSQQNLTKQTGLS 2385
                  G  G S   K+S +  +  P+ A+T+ S     S   P +     +++ +T +S
Sbjct: 7832 GLRESSGSEGTSSGTKMSTV-LSKVPTGATTEISKEDVTSIPGPAQSTISPDISTRT-VS 7889

Query: 2386 KNASSIPRSESASKGLNQMNNGNGANKK--VELSRMSSTKSSGSESDRSERPVLVRQSTF 2443
              ++S   +ESA   +N   +  GA  +    L   S+T  + + S  S+     + ST 
Sbjct: 7890 WFSTSPVMTESAEITMNTHTSPLGATTQGTSTLDTSSTTSLTMTHSTISQGFSHSQMSTL 7949

Query: 2444 IKEAP------SPTLRRKLEESASFESLSPSSRPASPTRSQAQTPVLSPSLPDMSLSTHS 2497
            ++  P      SP L  K   S S  S SP++   SP  S     + S  LP  SL T  
Sbjct: 7950 MRRGPEDVSWMSPPLLEKTRPSFSLMS-SPATTSPSPVSSTLPESISSSPLPVTSLLTSG 8008

Query: 2498 SVQAGGWRKLPPNLSPTIEYNDGRPAKRHDIARSHSESPSRLPINRSGT----------- 2546
                                     AK  D+    SE  +  P N S T           
Sbjct: 8009 L------------------------AKTTDMLHKSSEPVTNSPANLSSTSVEILATSEVT 8044

Query: 2547 --WKREHSKHSSSLPRVSTWRRTGSSSSILSASSESSE-------KAKSEDEKHVNSISG 2597
               ++ H   + ++  V T      S+S + A S++S+        +  ED     S  G
Sbjct: 8045 TDTEKTHPSSNRTVTDVGTSSSGHESTSFVLADSQTSKVTSPMVITSTMEDTSVSTSTPG 8104

Query: 2598 TKQSKENQVSAKGT----WRKIKENEFSPTNSTSQTVSSGATNGAESKTLIYQMAPAVSK 2653
              ++   Q     +     RK   +E +   +   TV SG   GA ++    ++  +   
Sbjct: 8105 FFETSRIQTEPTSSLTLGLRKTSSSEGTSLATEMSTVLSGVPTGATAEVSRTEVTSSSRT 8164

Query: 2654 TEDVWVRIEDCPINNPRSGRSPTGNTPPVIDSVSEKANPNIKDSKDNQAKQNVGNGSVPM 2713
            +   + ++   P  +     + T    P    ++E A   IK   D          +V +
Sbjct: 8165 SISGFAQLTVSPETS-----TETITRLPTSSIMTESAEMMIKTQTDPPGSTPESTHTVDI 8219

Query: 2714 RTVGLENRLNSFIQVDAPDQKGTEIKPGQNNPVPVSETNESSIVERTPFSSSSSSKHSSP 2773
             T       +S +       + T +     +P  +   ++SS+ E    +SS+SS  S P
Sbjct: 8220 STTPNWVETHSTVTQRFSHSEMTTLV--SRSPGDMLWPSQSSVEE----TSSASSLLSLP 8273

Query: 2774 SGTVAARVTPFNYNPSPRKSSADSTSARPSQIPTPVNNNTKKRDSKTDSTESSGTQSPKR 2833
            + T  + V+       P  S   ++   P  + T  +     R+  T ST +  + S +R
Sbjct: 8274 ATTSPSPVSSTLVEDFPSASLPVTSLLNPGLVIT-TDRMGISREPGTSSTSNLSSTSHER 8332



 Score = 52.4 bits (124), Expect = 6e-06
 Identities = 146/688 (21%), Positives = 250/688 (36%), Gaps = 124/688 (18%)

Query: 2205 SNSEISGQM-KQPLQANMPSISRGRTMIHIPGVRNSSSSTSPVSKKGPP-LKTPASK--- 2259
            S S +S +M K P   ++P  S   T         ++ ++ PV+  GPP L T AS    
Sbjct: 2188 SESLVSFRMNKDPWTVSIPLGSHPTT---------NTETSIPVNSAGPPGLSTVASDVID 2238

Query: 2260 SPSEGQTATTSPRGAKPSVKSELSPVARQTSQIGGSSKAPSRSGSRDSTPSRPAQQPLSR 2319
            +PS+G  +        P+V    SP    T+     S  P ++     T S    +  SR
Sbjct: 2239 TPSDGAESI-------PTVSFSPSPDTEVTT----ISHFPEKTTHSFRTISSLTHELTSR 2287

Query: 2320 PIQSPG---RNSISPGRNGISPPNKLSQLPRTSSPSTASTKSSGSGKMSYTSPGRQMSQQ 2376
                PG    +++S    G SP   L +  R +  S A T S      S+T         
Sbjct: 2288 VTPIPGDWMSSAMSTKPTGASPSITLGE--RRTITSAAPTTSPIVLTASFTETSTVSLDN 2345

Query: 2377 NLTKQTGL---SKNASSIPRSESASKGLNQMNNGNGANKKVELSRMSSTKSSGSESDRSE 2433
              T +T     ++  + +P   S+S  L         N  +  S M  TK++        
Sbjct: 2346 ETTVKTSDILDARKTNELPSDSSSSSDL--------INTSIASSTMDVTKTASI------ 2391

Query: 2434 RPVLVRQSTFIKEAPSPTLRRKLEESASFESLSPSSRPASPTRSQAQTPVLSPSLPDMSL 2493
                           SPT    +  S+S  SL  S RP  PT +       SPS+   + 
Sbjct: 2392 ---------------SPTSISGMTASSS-PSLFSSDRPQVPTSTTETNTATSPSVSSNTY 2435

Query: 2494 STHSSVQAGGW-RKLPP-NLSPTIEYND-----GRPAKRHDIARSHSESPSRLPINRSGT 2546
            S       GG    LPP  ++  +E +       RP +      S   +    P + +  
Sbjct: 2436 SLDGGSNVGGTPSTLPPFTITHPVETSSALLAWSRPVRTFSTMVSTDTASGENPTSSNSV 2495

Query: 2547 WKREHSKHSSSLPRVSTWRRTGSSSSI-------LSASSESSEKAKSEDE------KHVN 2593
                     +S+P   TW   GS++ +        S + E+     S  E       H++
Sbjct: 2496 --------VTSVPAPGTWTSVGSTTDLPAMGFLKTSPAGEAHSLLASTIEPATAFTPHLS 2547

Query: 2594 S--ISGTKQSKENQVSAKGTWRKIKENEFSPTNSTSQTVSSGATNGAESKTLIYQMAPAV 2651
            +  ++G+  + E  +      + I  +  +PT  TS   ++  T+      L+       
Sbjct: 2548 AAVVTGSSATSEASLLTTSESKAIHSSPQTPTTPTSG--ANWETSATPESLLVVTETSDT 2605

Query: 2652 SKTEDVWV-------RIEDCPINNPRSGRSPTGNTP------PVIDSVSEKANPNIKDSK 2698
            + T  + V        +   P   P +G     + P      P I   + +   ++  S 
Sbjct: 2606 TLTSKILVTDTILFSTVSTPPSKFPSTGTLSGASFPTLLPDTPAIPLTATEPTSSLATSF 2665

Query: 2699 DNQAKQNVGN---GSVPMRTVGLENRLNS----FIQVDAPDQK--GTEIKPGQNNPVPVS 2749
            D+     + +   G+VP  T+ +    N        V  PD+   G  I+    +P+  S
Sbjct: 2666 DSTPLVTIASDSLGTVPETTLTMSETSNGDALVLKTVSNPDRSIPGITIQGVTESPLHPS 2725

Query: 2750 ETNESSIV--ERTPFSSSSSSKHSS-PSGTVAARVTPFNYNPSPRKSSADSTSARPSQIP 2806
             T+ S IV    T +  S +   S+ P+GT  + V   +   S   +  DS++       
Sbjct: 2726 STSPSKIVAPRNTTYEGSITVALSTLPAGTTGSLVFSQSSENSETTALVDSSAGLERASV 2785

Query: 2807 TPVNNNTKKRDS----KTDSTESSGTQS 2830
             P+   ++   S    ++ ST S+GT++
Sbjct: 2786 MPLTTGSQGMASSGGIRSGSTHSTGTKT 2813



 Score = 50.1 bits (118), Expect = 3e-05
 Identities = 148/686 (21%), Positives = 260/686 (37%), Gaps = 108/686 (15%)

Query: 2125 SRQASSDSDSILSLKSGISLGSPFHLTPDQEEKP----FTSNKGPRILKPGEK--STLET 2178
            S + +S   S++SL S ++  SP + TP +         TS   P ++K  +   ++LE 
Sbjct: 8846 SVEKTSPPSSLVSL-SAVTSPSPLYSTPSESSHSSPLRVTSLFTPVMMKTTDMLDTSLEP 8904

Query: 2179 KKIESESKGIKGGKKVYKSLITGKVRSNSEISGQMKQPLQANMPSIS-RGRTMIHIPGVR 2237
                  S  I   +    SL T K    +E     +      M +IS R       PG+ 
Sbjct: 8905 VTTSPPSMNITSDE----SLATSKATMETEAIQLSENTAVTQMGTISARQEFYSSYPGLP 8960

Query: 2238 NSSSSTSPVSKKGPPLKTPASKSPSEGQTATTSPRGAKPSVKSELSPVARQTSQIGGSSK 2297
              S  TSPV           + S  +   +TT P        SE++ +  +++    S+ 
Sbjct: 8961 EPSKVTSPV----------VTSSTIKDIVSTTIP------ASSEITRIEMEST----STL 9000

Query: 2298 APSRSGSRDSTPSRPAQQPLSRPIQSPGRNSISPGRNGISPPNKLSQLPRTSSPSTASTK 2357
             P+           P +   S+ I S  + S  P +   S          T   S     
Sbjct: 9001 TPT-----------PRETSTSQEIHSATKPSTVPYKALTSA---------TIEDSMTQVM 9040

Query: 2358 SSGSGKMSYTSPGRQMSQQNLTKQTGLSKNASSIPRSESASKGLNQMNNGNGANKKVELS 2417
            SS  G     SP +    Q+++ +  +++ ++S  ++ES    +       GA  +  L+
Sbjct: 9041 SSSRGP----SPDQSTMSQDISTEV-ITRLSTSPIKTESTEMTITTQTGSPGATSRGTLT 9095

Query: 2418 RMSSTK-SSGSESDRSERPVLVRQSTFIKEAPS--PTLRRKLEE---SASFESLSPSSRP 2471
              +ST   SG+ S  S+     + +  +   P   P L     E   SASF   SP    
Sbjct: 9096 LDTSTTFMSGTHSTASQGFSHSQMTALMSRTPGDVPWLSHPSVEEASSASFSLSSPVMTS 9155

Query: 2472 ASPTRSQAQTPVLSPSLPDMSLSTHSSVQ--------AGGWRKLPPNLSPTIEYNDGRPA 2523
            +SP  S     + S SLP  SL T   V+        +      PPNLS T        A
Sbjct: 9156 SSPVSSTLPDSIHSSSLPVTSLLTSGLVKTTELLGTSSEPETSSPPNLSST-------SA 9208

Query: 2524 KRHDIARSHSESPSRLPINRSGTWKREHSKHSSSLPRVSTWRRTGS--------SSSILS 2575
            +   I    +++  +L +    T    H   SS L    T + T S         +++L+
Sbjct: 9209 EILAITEVTTDT-EKLEMTNVVTSGYTHESPSSVLADSVTTKATSSMGITYPTGDTNVLT 9267

Query: 2576 ASSESSEKAKSEDEKHVNSISGTKQSKENQVSAKGTWRKIKENEFSPTNSTSQTVSSGAT 2635
            ++   S+ ++ + +  ++   G  ++  ++ ++  T  K       PT +T++   + A 
Sbjct: 9268 STPAFSDTSRIQTKSKLSLTPGLMETSISEETSSAT-EKSTVLSSVPTGATTEVSRTEAI 9326

Query: 2636 NGAESKTLIYQMAPAVSKTEDVWVRIEDCPINNPRSGRSPTGNTPPVIDSVSEKANPNIK 2695
              + S+T I   A +   ++     I    I+ P + +  T        +++ K  P+  
Sbjct: 9327 --SSSRTSIPGPAQSTMSSDTSMETI--TRISTPLTRKESTDM------AITPKTGPSGA 9376

Query: 2696 DSKDNQAKQNVGNGSVPMRTVGLENRLNSFIQVDAPDQKGTE-------IKPGQNNPVPV 2748
             S+      +    S P        R    + V  P  +G E       +   +N+P P 
Sbjct: 9377 TSQGTFTLDSSSTASWPGTHSATTQRFPQSV-VTTPMSRGPEDVSWPSPLSVEKNSP-PS 9434

Query: 2749 SETNESSIVERTP-FSSSSSSKHSSP 2773
            S  + SS+   +P +S+ S S HSSP
Sbjct: 9435 SLVSSSSVTSPSPLYSTPSGSSHSSP 9460



 Score = 49.3 bits (116), Expect = 5e-05
 Identities = 141/642 (21%), Positives = 235/642 (36%), Gaps = 91/642 (14%)

Query: 2221  MPSISRGRTMIHIPGV-RNSSSSTSPVSK--KGP---PLKTPASKSPSEGQTATTSPRGA 2274
             MPS+S   T     GV R  S S SP S+   GP    L T A   PS    +T  P  +
Sbjct: 10279 MPSLSEAMTSFATTGVPRAISGSGSPFSRTESGPGDATLSTIAESLPS----STPVPFSS 10334

Query: 2275  KPSVKSELSPVARQTSQIGGSSKAPSRSGSRDSTPSRPAQQPLSRPIQSPGRNSISPGRN 2334
                  ++ S +     +I  SS  P R  +   T S   +  L                 
Sbjct: 10335 STFTTTDSSTIPA-LHEITSSSATPYRVDTSLGTESSTTEGRLVM--------------- 10378

Query: 2335  GISPPNKLSQLPRTSSPSTASTKSSGSGKMSYTSPGRQMSQQN--LTKQTGLSKNASSIP 2392
              +S  +  SQ  RTSS     T+ + S ++   +   Q+   +  LT+  G+ ++ + IP
Sbjct: 10379 -VSTLDTSSQPGRTSSSPILDTRMTESVELGTVTSAYQVPSLSTRLTRTDGIMEHITKIP 10437

Query: 2393  RSESASKGLNQMNNGNGANKKVELSRMSSTKSSGSESDRSERPVLVRQSTFIKEAPSPTL 2452
              +E+A +G   +    G       +      + G++   +    L   +T +K     TL
Sbjct: 10438 -NEAAHRGT--IRPVKGPQTSTSPASPKGLHTGGTKRMETTTTALKTTTTALKTTSRATL 10494

Query: 2453  RRKLEESA--SFESLSPSSRPAS--PTRSQAQTPVLSPSLPDMSLSTHSSVQAGGWRKLP 2508
                +      +   L+ S + AS  PT     TP + P +P+ + S  +S+ A       
Sbjct: 10495 TTSVYTPTLGTLTPLNASMQMASTIPTEMMITTPYVFPDVPETTSSLATSLGA------- 10547

Query: 2509  PNLSPTIEYNDGRPAKRHDIARSHSESPSRLPINRSGTWKREHSKHSSSLPRVSTWRRTG 2568
                    E +   P     +    SE+ + L ++RSG    E S    +L   S+   T 
Sbjct: 10548 -------ETSTALPRTTPSVFNRESETTASL-VSRSGA---ERSPVIQTLDVSSSEPDTT 10596

Query: 2569  SSSSILSASSESSEKAKSEDEKH--VNSISGTKQSKENQVSAKGTWRKIKENEFSPTNST 2626
             +S  I  A +  +    + +  H  ++++S T  S    VS+      I  +E      T
Sbjct: 10597 ASWVIHPAETIPTVSKTTPNFFHSELDTVSSTATSHGADVSS-AIPTNISPSELDAL--T 10653

Query: 2627  SQTVSSGATNGAESKTLIYQMAPAVSKTEDVWVRIEDCPINNPRSGRSPTGNTPPVIDSV 2686
                  SG        TL    +P  ++T   W       + +P    S    T P     
Sbjct: 10654 PLVTISGTDTSTTFPTL--TKSPHETETRTTW-------LTHPAETSSTIPRTIPNFSHH 10704

Query: 2687  SEKANPNIKDSKDNQAKQNVGNGSVPMRTV--GLENRLNSFIQVDAPDQKGT----EIKP 2740
                A P+I  S   +      + ++P+ TV  G E+ + S +     D+  T     + P
Sbjct: 10705 ESDATPSIATSPGAET-----SSAIPIMTVSPGAEDLVTSQVTSSGTDRNMTIPTLTLSP 10759

Query: 2741  GQNNP----VPVSETNESSIVERTPFSSSSSSKHSSPSGTVAARVTPFN---YNPSPRKS 2793
             G+       V   E   SS +  +  S + S   +S   ++AA+ +  N    N     +
Sbjct: 10760 GEPKTIASLVTHPEAQTSSAIPTSTISPAVSRLVTSMVTSLAAKTSTTNRALTNSPGEPA 10819

Query: 2794  SADSTSARPSQIPTPVNNNT-----KKRDSKTDSTESSGTQS 2830
             +  S    P+Q    V   T      K D+    T S G +S
Sbjct: 10820 TTVSLVTHPAQTSPTVPWTTSIFFHSKSDTTPSMTTSHGAES 10861



 Score = 48.1 bits (113), Expect = 1e-04
 Identities = 128/633 (20%), Positives = 226/633 (35%), Gaps = 102/633 (16%)

Query: 2231 IHIPGVRNSSSSTSPVSKKGPPL---KTPASKSPSEGQTATT---SPRGAKPSVKSELSP 2284
            IH  G   S SS SP +   P +   KT  S S       T+   +   + PSV    + 
Sbjct: 821  IHPTGTLTSESSESPSTLSLPSVSGVKTTFSSSTPSTHLFTSGEETEETSNPSVSQPETS 880

Query: 2285 VARQTSQIGGSSKAPSRSGSRDSTPSRPAQQPLSRPIQSPGRNSISPGRNGISPPNKLSQ 2344
            V+R  + +  +S       + D+ P+R AQ                      S  + +S+
Sbjct: 881  VSRVRTTLASTSVPTPVFPTMDTWPTRSAQ---------------------FSSSHLVSE 919

Query: 2345 LPRTSSPSTASTKSSGSGKMSYTSPGRQMSQQNLTKQTGLSKNASSIPRSESASKGLNQM 2404
            L  TSS S  ++  S   K+S+ +    MSQ N       + N S+ P+S +  +   + 
Sbjct: 920  LRATSSTSVTNSTGSALPKISHLTGTATMSQTNRD-----TFNDSAAPQSTTWPETSPRF 974

Query: 2405 NNGNGANKKVELSRMSSTKSSGSESDRSERPVLVRQSTFIKEAPSPTLRRKLEE-SASFE 2463
              G        L   ++T S+ + S        V  S F   A S      + E S +  
Sbjct: 975  KTG--------LPSATTTVSTSATS----LSATVMVSKFTSPATSSMEATSIREPSTTIL 1022

Query: 2464 SLSPSSRPASPTRSQAQTPVLSPSLPDMSLSTHSSVQAGGWRKLPPNLSPTIEYNDGRPA 2523
            +   ++ P S   +    P+    + +  L T           LP   + + E +     
Sbjct: 1023 TTETTNGPGSMAVASTNIPIGKGYITEGRLDT---------SHLPIGTTASSETSMDFTM 1073

Query: 2524 KRHDIARSHSESPSRLPINRSGTWKREHSKHSSSLPRVSTWRRTGSSSSILSASSESSEK 2583
             +  ++ S S S S   ++ +G         SS+  R S +  T S       S E +  
Sbjct: 1074 AKESVSMSVSPSQS---MDAAG---------SSTPGRTSQFVDTFSDDVYHLTSREITIP 1121

Query: 2584 AKSEDEKHVNSISGTKQSKENQVSAKGTWRKIKENEFSPTNSTSQTVSSG--ATNGAESK 2641
                       ++ T     +  SA+ TW  I  +  SP++ T +   S   +T    + 
Sbjct: 1122 RDGTSSALTPQMTATHPPSPDPGSARSTWLGILSS--SPSSPTPKVTMSSTFSTQRVTTS 1179

Query: 2642 TLIYQMAPAVSKTEDVWVRIEDCPINNPRSGRSPTGNTPPVIDSVSEKANPNIKDSKDNQ 2701
             ++  +  +     ++       P N P SG        P+             D+    
Sbjct: 1180 MIMDTVETSRWNMPNLPSTTSLTPSNIPTSGAIGKSTLVPL-------------DTPSPA 1226

Query: 2702 AKQNVGNGSVPMRTVGLEN------RLNSFIQVDAPD----QKGTEIKPGQNNPV--PVS 2749
                   G +P  +   E+       L +    ++P        + +KPG   P+  P  
Sbjct: 1227 TSLEASEGGLPTLSTYPESTNTPSIHLGAHASSESPSTIKLTMASVVKPGSYTPLTFPSI 1286

Query: 2750 ETNESSIVERTPFSSSSSSKHSSPSGTVAARVTPFNYNPSPRKSSADSTSARPSQIPTPV 2809
            ET+      R  +SS SS + ++P  T     T   ++P+   ++ D      +Q+ TP 
Sbjct: 1287 ETHIHVSTARMAYSSGSSPEMTAPGET----NTGSTWDPTTYITTTDPKDTSSAQVSTPH 1342

Query: 2810 NNNTKKRDSKTDSTESSGTQSPKRHSGSYLVTS 2842
            +  T +       TES+   +P  +SGS  ++S
Sbjct: 1343 SVRTLRTTENHPKTESA---TPAAYSGSPKISS 1372



 Score = 47.8 bits (112), Expect = 2e-04
 Identities = 331/1770 (18%), Positives = 603/1770 (34%), Gaps = 257/1770 (14%)

Query: 1177 IDYSLKYATDIPSSQKQSFSFSKSSSGQSSKTEHMSSSSENTSTPSSNAKRQNQLHPSSA 1236
            +D SL+  T  P S   +      +S  ++  E        T+ PS N    N     SA
Sbjct: 4790 VDTSLETVTSSPQSMSNTLDDISVTSAATTDIE--------TTHPSINTVVTNVGTTGSA 4841

Query: 1237 -QSRSGQPQKAATCKVSSINQETIQTYCVEDTPICFSRCSSLSSLSSAEDEIGCNQTTQE 1295
             +S S         KV+S N   + T  +EDT I  S   S S  +  E E   + T + 
Sbjct: 4842 FESHSTVSAYPEPSKVTSPN---VTTSTMEDTTISRSIPKS-SKTTRTETETTSSLTPKL 4897

Query: 1296 ADSANTLQIAEIKEKIGTRSAEDPVSEVP-AVSQHPRTKSSRLQGSSLSSESARHKAVEF 1354
             +++ + +I        T ++  P  E+  A ++  RT  +    +S         +++ 
Sbjct: 4898 RETSISQEITS-----STETSTVPYKELTGATTEVSRTDVTSSSSTSFPGPDQSTVSLDI 4952

Query: 1355 SSGAKSP-SKSGAQTPKSPPEHYVQETPLMFSRCTSVSSLDSFESRSIASSVQSEPCSGM 1413
            S+   +  S S   T  +      Q  P         +S D+F      ++ Q+   S M
Sbjct: 4953 STETNTRLSTSPIMTESAEITITTQTGP------HGATSQDTFTMDPSNTTPQAGIHSAM 5006

Query: 1414 VSGIIS------PSDLPDSPGQTMPPSRSKTPPPPPQTAQTKREVPKNKAPTA-EKRESG 1466
              G          S +P     T PPS  KT  P    +      P   + T  E + S 
Sbjct: 5007 THGFSQLDVTTLMSRIPQDVSWTSPPSVDKTSSPSSFLSSPAMTTPSLISSTLPEDKLSS 5066

Query: 1467 PKQAAVNAAVQRVQVLPDADTLLHFATESTPDGFSCSSSLSALSLDEPFIQKDVELRIMP 1526
            P  + + + +  V++     T L   T S P+  S S  + A S D     KD +  I P
Sbjct: 5067 PMTSLLTSGL--VKITDILRTRLEPVTSSLPNFSSTSDKILATSKDS----KDTK-EIFP 5119

Query: 1527 P-------VQENDNGNET------ESEQPKESNENQEKEAEKTIDSEKDLLDDSDDDDIE 1573
                    V+ N++G+E+      +SE PK + +               +      +   
Sbjct: 5120 SINTEETNVKANNSGHESHSPALADSETPKATTQMVITTTVGDPAPSTSMPVHGSSETTN 5179

Query: 1574 ILEECIISAMP----TKSSRKAKKPAQTA---SKLPPPVARKPSQLPVYKLLPSQNRLQP 1626
            I  E      P    T +S+++  P  T+   SK+P     + S   V     S     P
Sbjct: 5180 IKREPTYFLTPRLRETSTSQESSFPTDTSFLLSKVPTGTITEVSSTGVNS---SSKISTP 5236

Query: 1627 QKHVSFTPGD----DMPRVYCVEGTPINFSTATSLSDLTIESPPNELAAGEGVRGGAQSG 1682
                S  P D    ++PRV+       +  T ++   +T ++ P E A+   +       
Sbjct: 5237 DHDKSTVPPDTFTGEIPRVFTS-----SIKTKSAEMTITTQASPPESASHSTL------- 5284

Query: 1683 EFEKRDTIPTEGRSTDEAQG--------------GKTSSVTIPELDDNKAEEGDILAEC- 1727
              +   T+   G  +   QG              G  S +T P +++  +    + +   
Sbjct: 5285 PLDTSTTLSQGGTHSTVTQGFPYSEVTTLMGMGPGNVSWMTTPPVEETSSVSSLMSSPAM 5344

Query: 1728 -----INSAMPKGKSHKPFRVKKIMDQV-----------QQASASSSAPNKNQLDGKKK- 1770
                 ++S  P+     P  V  +   V              S +SS PN + +  ++  
Sbjct: 5345 TSPSPVSSTSPQSIPSSPLPVTALPTSVLVTTTDVLGTTSPESVTSSPPNLSSITHERPA 5404

Query: 1771 --KPTSPVKPIPQNTEYRTRVRKNADSKNNLNAERVFSDNKDSKKQNLKNNSKVFNDKLP 1828
              K T+  +    ++              + +   V +D++ SK   L + +    D   
Sbjct: 5405 TYKDTAHTEAAMHHSTNTAVTNVGTSGSGHKSQSSVLADSETSKATPLMSTTSTLGDT-- 5462

Query: 1829 NNEDRVRGSFAFDSPHHYTPIEGTPYCFSRNDSLSSLDFDDDDVDLSREKAELRKAKENK 1888
                 V  S    S  +    E T     R    S+ +      + +   + +      +
Sbjct: 5463 ----SVSTSTPNISQTNQIQTEPTASLSPRLRESSTSEKTSSTTETNTAFSYVPTGAITQ 5518

Query: 1889 ESEAKVTSHTELTSNQQSANKTQAIAKQPINRGQPKPILQK--------QSTFPQSSKDI 1940
             S  +++S     S+         I+   I R    PI+ K        Q+T P ++   
Sbjct: 5519 ASRTEISSSRTSISDLDRPTIAPDISTGMITRLFTSPIMTKSAEMTVTTQTTTPGATSQG 5578

Query: 1941 PDRGAATDEKLQNFAIENTPVCFSHNSSLSSLSDIDQENNNKENEPIKETEPPDSQGEPS 2000
                  +    Q          F H+   +  S    + +     P++ET    S   PS
Sbjct: 5579 ILPWDTSTTLFQGGTHSTVSQGFPHSEITTLRSRTPGDVSWMTTPPVEETSSGFSLMSPS 5638

Query: 2001 KPQ---ASGYAPKSFHVEDTPVCFSRNSSLSSLSIDSEDDL---LQECISSAMPKKKKPS 2054
                   S  +P+S      PV     + L+S+ + + + L     E ++S+ P    P+
Sbjct: 5639 MTSPSPVSSTSPESIPSSPLPV----TALLTSVLVTTTNVLGTTSPEPVTSSPPNLSSPT 5694

Query: 2055 RLKGDNEKHSPRNMGGILGEDLTLDLKDIQRPDSEHGLSPDSENFDWKAIQEGANSIVSS 2114
            + +    K +               + ++    S H               E  +S+ + 
Sbjct: 5695 QERLTTYKDTAHTEAMHASMHTNTAVANVGTSISGH---------------ESQSSVPAD 5739

Query: 2115 LHQAAAAACLSRQASSDSDSILSLKSGISLGSP-FHLTPDQEEKPFTSNKGPRILKPGEK 2173
             H + A + +    +    S+       S  +P F  T  Q E   +   G R  +  E+
Sbjct: 5740 SHTSKATSPMGITFAMGDTSV-------STSTPAFFETRIQTESTSSLIPGLRDTRTSEE 5792

Query: 2174 --STLETKKIESESKGIKGGKKVYKSLITGKVRSNSEISG--QMKQPLQANMPSISRGRT 2229
              +  ET  + SE       +     +IT    S + ISG    K     +  +I+R  T
Sbjct: 5793 INTVTETSTVLSEVPTTTTTEVSRTEVITS---SRTTISGPDHSKMSPYISTETITRLST 5849

Query: 2230 MIHIPGVRNSSSSTSPVSKKGPPLKTPASKSPSEGQTATTSPRGAKPSVKSELSPVARQT 2289
               + G     S+   ++ +  P+ T +  + +   ++T S  G    V     P + +T
Sbjct: 5850 FPFVTG-----STEMAITNQTGPIGTISQATLTLDTSSTASWEGTHSPVTQRF-PHSEET 5903

Query: 2290 SQIGGSSKAPSRSGSRDSTPSRPAQQPLSRPIQSPGRNSISPGRNGISPPNKLSQLPRTS 2349
            + +  S+K  S      S PS       S P+  P   S S   + +S  +  S LP TS
Sbjct: 5904 TTMSRSTKGVSWQ----SPPSVEETSSPSSPVPLPAITSHSSLYSAVSGSSPTSALPVTS 5959

Query: 2350 SPSTASTKSSGSGKMSYTSPGRQMSQQNLTKQTGLSKNASSIPRSESASKGLNQMNNGNG 2409
                              + GR+ +   L   + L    SS+P + S S G    +  + 
Sbjct: 5960 ----------------LLTSGRRKTIDMLDTHSELV--TSSLPSASSFS-GEILTSEAST 6000

Query: 2410 ANKKVELSRMSSTKSSGSESDRSERPVLVRQSTFIKEAPSPTLRRKLEESASFESLSPSS 2469
              + +  S  ++  + G+ +   +    +  S  I   PS     K+  S   +++  +S
Sbjct: 6001 NTETIHFSENTAETNMGTTNSMHK----LHSSVSIHSQPSGHTPPKVTGSMMEDAIVSTS 6056

Query: 2470 RPASPTRSQAQTPVLSPSLPDM----------------------SLSTHSSVQAGGWRKL 2507
             P SP          SP  P++                      SL   + V        
Sbjct: 6057 TPGSPETKNVDRDSTSPLTPELKEDSTALVMNSTTESNTVFSSVSLDAATEVSRAEVTYY 6116

Query: 2508 PPNLSPTIEYNDGRPAKRHDIARSHSESPSRLPINRSGTWKREHSKHSSSLPRVSTWRRT 2567
             P   P    +   P    + + SHS SP  L I+   T   +      +    S  + T
Sbjct: 6117 DPTFMPASAQSTKSPDISPEASSSHSNSPP-LTISTHKTIATQTGPSGVT----SLGQLT 6171

Query: 2568 GSSSSILSASSESSEKAKSEDEKHVNSISGTKQS---KENQVSAKGTWRKIKENEFSPTN 2624
              +S+I +++   S + +   +    S+     +   K +  SA+       +     T 
Sbjct: 6172 LDTSTIATSAGTPSARTQDFVDSETTSVMNNDLNDVLKTSPFSAEEANSLSSQAPLLVTT 6231

Query: 2625 STSQTVSSGATNGAESKTLIYQM-APAVSKTEDVWVRIEDCPINNPRSGRSPTGNTPPVI 2683
            S S   S+   +   S   +  +  P ++K  D+   +E     +P++ R+    +    
Sbjct: 6232 SPSPVTSTLQEHSTSSLVSVTSVPTPTLAKITDMDTNLEPV-TRSPQNLRNTLATSEATT 6290

Query: 2684 DSVSEKANPNIKDSKDNQAKQNVGNGSVPMRTVGLENRLNSFIQVDAPDQKGTEIKPGQN 2743
            D  +   +P+I     N A  NVG  S P       N     +  D+   K T       
Sbjct: 6291 D--THTMHPSI-----NTAVANVGTTSSP-------NEFYFTVSPDSDPYKAT------- 6329

Query: 2744 NPVPVSETNESSIVERTPFSSSSSSKHSSPSGTVAARVTPFNYNPSPRK--SSADSTSAR 2801
            + V ++ T+  SIV  +   SS+  K  S   T  + +       + +K  SS+D+++  
Sbjct: 6330 SAVVITSTSGDSIVSTSMPRSSAMKKIESE--TTFSLIFRLRETSTSQKIGSSSDTSTVF 6387

Query: 2802 PSQIPTPVNNNTKKRDSKTDSTESSGTQSP 2831
                       ++   + +  T   GT+ P
Sbjct: 6388 DKAFTAATTEVSRTELTSSSRTSIQGTEKP 6417



 Score = 47.4 bits (111), Expect = 2e-04
 Identities = 329/1706 (19%), Positives = 580/1706 (33%), Gaps = 175/1706 (10%)

Query: 1200  SSSGQSSKTEHMSSSSENTSTPSSNAKRQNQLHPSSAQSRSGQPQKAATCKVSSINQETI 1259
             SS  ++S   ++SS+S      S   K + ++HPSS    +       T     ++  ++
Sbjct: 8608  SSEPETSSPPNLSSTSAEILATSEVTKDREKIHPSS----NTPVVNVGTVIYKHLSPSSV 8663

Query: 1260  QTYCVEDTPIC-FSRCSSLSSLSSAEDEIGCNQTTQ-EADSANTLQIAEIKEKIGTRSAE 1317
                 V   P    +  S+L + S +       +T   +  S+ T  + EI     T SA 
Sbjct: 8664  LADLVTTKPTSPMATTSTLGNTSVSTSTPAFPETMMTQPTSSLTSGLREISTSQETSSAT 8723

Query: 1318  DPVSEVPAVSQHPRTKSSRLQGSSLSSESARHKA-----VEFSSGAKSPSKSGAQTPKSP 1372
             +  + +  +     TK SR +  SL   S    A      E S+   +   +   T  S 
Sbjct: 8724  ERSASLSGMPTGATTKVSRTEALSLGRTSTPGPAQSTISPEISTETITRISTPLTTTGSA 8783

Query: 1373  PEHYVQETPLMFSRCTSVSSLDSFESRSIASSVQSEPCSGMVSGIISP-SDLPDSPGQTM 1431
                   +T    +      +LD+    S   +  +       SG+ +P S  P+      
Sbjct: 8784  EMTITPKTGHSGASSQGTFTLDTSSRASWPGTHSAATHRSPHSGMTTPMSRGPEDVSWPS 8843

Query: 1432  PPSRSKTPPPPPQTAQTKREVPKNKAPT-AEKRESGPKQAAVNAAVQRVQVLPDADTLLH 1490
              PS  KT PP    + +    P     T +E   S P +         ++     DT L 
Sbjct: 8844  RPSVEKTSPPSSLVSLSAVTSPSPLYSTPSESSHSSPLRVTSLFTPVMMKTTDMLDTSLE 8903

Query: 1491  FATESTP-----DGFSCSSSLSALSLDEPFIQKDVELRIMPPVQENDNGNETESEQPKES 1545
               T S P        S ++S + +  +   + ++  +  M  +        +    P+ S
Sbjct: 8904  PVTTSPPSMNITSDESLATSKATMETEAIQLSENTAVTQMGTISARQEFYSSYPGLPEPS 8963

Query: 1546  NENQEKEAEKTIDSEKDLLDDSDDDDIEILEECIISAMPTKSSRKAKKPAQTASKLPPPV 1605
                       TI   KD++  +     EI    + S     +S     P +T++      
Sbjct: 8964  KVTSPVVTSSTI---KDIVSTTIPASSEITRIEMES-----TSTLTPTPRETSTSQEIHS 9015

Query: 1606  ARKPSQLPVYKLLPSQNRLQPQKHV-SFTPGDDMPRVYCVEGTPINFSTATSLSDLTIES 1664
             A KPS +P YK L S         V S + G    +    +       T  S S +  ES
Sbjct: 9016  ATKPSTVP-YKALTSATIEDSMTQVMSSSRGPSPDQSTMSQDISTEVITRLSTSPIKTES 9074

Query: 1665  PPNELAAGEGVRGGAQSGEFEKRDTIPT--EGRSTDEAQGGKTSSVT---------IPEL 1713
                 +    G  G    G     DT  T   G  +  +QG   S +T         +P L
Sbjct: 9075  TEMTITTQTGSPGATSRGTL-TLDTSTTFMSGTHSTASQGFSHSQMTALMSRTPGDVPWL 9133

Query: 1714  DDNKAEEGDILAECINSAMPKGKSHKPFRVKKIMDQVQQASASSSAPNKNQLDGKKKKPT 1773
                  EE    +  ++S +    S        +   +  +  SSS P  + L     K T
Sbjct: 9134  SHPSVEEASSASFSLSSPVMTSSS-------PVSSTLPDSIHSSSLPVTSLLTSGLVKTT 9186

Query: 1774  -------SPVKPIPQNTEYRTRVRKNADSKNNLNAERVFSDNKDSKKQNLKNNSKVFNDK 1826
                     P    P N    T     A ++   + E++   N  +     ++ S V  D 
Sbjct: 9187  ELLGTSSEPETSSPPNLS-STSAEILAITEVTTDTEKLEMTNVVTSGYTHESPSSVLADS 9245

Query: 1827  LPNNEDRVRGSFAFDSPHHYTPIEGTPYCFSRNDSLSSLDFDDDDVDLSREKAELRKAKE 1886
             +     +   S     P   T +  +   FS    + +       + L+    E   ++E
Sbjct: 9246  VTT---KATSSMGITYPTGDTNVLTSTPAFSDTSRIQT----KSKLSLTPGLMETSISEE 9298

Query: 1887  NKESEAKVTSHTEL-TSNQQSANKTQAIAKQPINRGQPKPILQKQSTFPQSSKDIPDRGA 1945
                +  K T  + + T      ++T+AI+    +   P        T  ++   I     
Sbjct: 9299  TSSATEKSTVLSSVPTGATTEVSRTEAISSSRTSIPGPAQSTMSSDTSMETITRIST--P 9356

Query: 1946  ATDEKLQNFAIENTPVCFSHNSSLSSLSDIDQENNNKENEPIKETEPPDSQGEPSKPQAS 2005
              T ++  + AI  TP      ++      +D  +          T     Q   + P + 
Sbjct: 9357  LTRKESTDMAI--TPKTGPSGATSQGTFTLDSSSTASWPGTHSATTQRFPQSVVTTPMSR 9414

Query: 2006  GYAPKSFHVEDTPVCFSRNSSLSSLSIDSEDDLLQECISSAMPKKKKPSRLKGDNEKHSP 2065
             G    S+    +P+   +NS  SSL   S        ++S  P    PS        HS 
Sbjct: 9415  GPEDVSW---PSPLSVEKNSPPSSLVSSSS-------VTSPSPLYSTPS-----GSSHSS 9459

Query: 2066  RNMGGILGEDLTLDLKDIQRPDSEHGLSPDSENFDWKAIQEGANSIVSSLHQAAAAACLS 2125
                   L   + +   D+     +  L P++ +     I    +   S       A  + 
Sbjct: 9460  PVPVTSLFTSIMMKATDM----LDASLEPETTSAPNMNITSDESLAASKATTETEAIHVF 9515

Query: 2126  RQASSDSDSILSLKSGISLGSPFHLTPDQEEKPFTSNKGPR-----ILKPGEK--STLET 2178
                ++      S    +   SP    P +   P  ++   R        PG    + +E 
Sbjct: 9516  ENTAASHVETTSATEELYSSSPGFSEPTKVISPVVTSSSIRDNMVSTTMPGSSGITRIEI 9575

Query: 2179  KKIESESKGIKGGKKVYKSLITGKVRSNSEISGQMKQPLQANMPSISRGRTM----IHIP 2234
             + + S + G++      ++  +  + S++E S  + +      P +SR   M      IP
Sbjct: 9576  ESMSSLTPGLR------ETRTSQDITSSTETSTVLYKMPSGATPEVSRTEVMPSSRTSIP 9629

Query: 2235  GVRNSSSSTSPVSKKGPPLKTPASKSPSEGQTATTSPRGAKPSVKSELSPVARQTSQIGG 2294
             G   S+ S     +    L T    + S   T TT   G   +      P+    + + G
Sbjct: 9630  GPAQSTMSLDISDEVVTRLSTSPIMTESAEITITTQ-TGYSLATSQVTLPLGTSMTFLSG 9688

Query: 2295  SSKAPSRSGSRDSTPSRPAQQPLSRPIQSPGRNSISPGRNGISPPNKLSQLPRTSSPSTA 2354
             +    S+  S     +  ++ P S    SP    +   R+  S    L+ LP T+S S  
Sbjct: 9689  THSTMSQGLSHSEMTNLMSRGPESLSWTSP--RFVETTRSSSS----LTSLPLTTSLSPV 9742

Query: 2355  ST---KSSGSGKMSYTS---PGRQMSQQNLTKQTGLSKNASSIPRSESASKGLNQMNNGN 2408
             S+    SS S  +  TS   PG   + + L   T      SS P   S S  +   +   
Sbjct: 9743  SSTLLDSSPSSPLPVTSLILPGLVKTTEVL--DTSSEPKTSSSPNLSSTSVEIPATSEIM 9800

Query: 2409  GANKKVELSRMSSTKS--SGSESDRSERPVLVRQSTFIKEAPSPTLRRKLEESASFESLS 2466
                +K+  S  ++     + S    S   VL    T I   PS  +   ++++  F S  
Sbjct: 9801  TDTEKIHPSSNTAVAKVRTSSSVHESHSSVLADSETTI-TIPSMGITSAVDDTTVFTSNP 9859

Query: 2467  PSSR----PASPTRSQAQTP---VLSPSLPDMSLSTHSSVQAGGWRKLPPNLSPTIEYND 2519
               S     P  PT S   TP     S S    S++  S+V  G    +P + +  +   +
Sbjct: 9860  AFSETRRIPTEPTFS--LTPGFRETSTSEETTSITETSAVLYG----VPTSATTEVSMTE 9913

Query: 2520  GRPAKRHDIARSHSESPSRLPINRSGTWKREHSKHSSSLPRVSTWRRT---GSSSSILSA 2576
                + R  I  S   + S   I    T     S  S S     T +++    ++ S L+ 
Sbjct: 9914  IMSSNRIHIPDSDQSTMSPDIITEVITRLSSSSMMSESTQMTITTQKSSPGATAQSTLTL 9973

Query: 2577  SSESSEKAKSEDEKHVNSISGTKQSKENQVSAKGTWRKIKENEFSPTNS--------TSQ 2628
             ++ ++  A++        +     +  ++     +W+     E + ++S        TS 
Sbjct: 9974  ATTTAPLARTHSTVPPRFLHSEMTTLMSRSPENPSWKSSLFVEKTSSSSSLLSLPVTTSP 10033

Query: 2629  TVSSGATNG--AESKTLIYQMAPAVSKTEDVWVRIEDCPINNPRSGRSPTGNTPPVIDSV 2686
             +VSS       + S ++   + P + KT D         ++   SG S        + + 
Sbjct: 10034 SVSSTLPQSIPSSSFSVTSLLTPGMVKTTDTSTE-PGTSLSPNLSGTSVEILAASEVTTD 10092

Query: 2687  SEKANPNIKDSKDNQAKQNVGNGSVPMRTVGLENRLNSFIQVDAPDQKGTEIKPGQNNPV 2746
             +EK +P+      + A  NVG       T    + L S + + +   K T        PV
Sbjct: 10093 TEKIHPS-----SSMAVTNVG-------TTSSGHELYSSVSIHSEPSKAT-------YPV 10133

Query: 2747  PV-SETNESSIVERTPFSSSSSSKHSSPSGTVAARVTPFNYNPSPRKSSADSTSARPSQI 2805
                S   E+SI    P +  ++   + P   + +     N        S D++S  P+  
Sbjct: 10134 GTPSSMAETSISTSMPANFETTGFEAEPFSHLTSGFRKTN-------MSLDTSSVTPTNT 10186

Query: 2806  PTPVNNNTKKRDSKTDSTESSGTQSP 2831
             P+   +    + SKTD T S+ T SP
Sbjct: 10187 PSSPGSTHLLQSSKTDFTSSAKTSSP 10212



 Score = 44.3 bits (103), Expect = 0.002
 Identities = 136/638 (21%), Positives = 245/638 (38%), Gaps = 113/638 (17%)

Query: 2233 IPGVRNSSSSTSPVSKKGPPLKTPASKSPSEGQTATTSPRGA--KPSVKSELSPVARQTS 2290
            IPG+     + SP+         P+S SPS+      +PR    + S+   LS +   T+
Sbjct: 2709 IPGITIQGVTESPLH--------PSSTSPSK----IVAPRNTTYEGSITVALSTLPAGTT 2756

Query: 2291 QIGGSSKAPSRSGSRDSTPSRPAQQPLSRPIQSPGRNSISPGRNGISPPNKLSQLPRTSS 2350
               GS      S + ++T    +   L R    P    ++ G  G++    +    R+ S
Sbjct: 2757 ---GSLVFSQSSENSETTALVDSSAGLERASVMP----LTTGSQGMASSGGI----RSGS 2805

Query: 2351 PSTASTKSSGSGKMSYTSPGRQMSQQNLTKQTGLSKNASSIPRS-----ESASKGLNQMN 2405
              +  TK+  S  ++  +PG   +   +T    L+   S+ P+       SA  GL    
Sbjct: 2806 THSTGTKTFSSLPLTM-NPGEVTAMSEITTNR-LTATQSTAPKGIPVKPTSAESGLLTPV 2863

Query: 2406 NGNGANKKVELSRMSSTKSSGSESDR-----SERPVLVRQSTFIKEAPSPTLRRKLEESA 2460
            + + +  K   S  ++  + G          SE P L  +S  +   P  +L    +  A
Sbjct: 2864 SASSSPSKAFASLTTAPPTWGIPQSTLTFEFSEVPSLDTKSASLP-TPGQSLNTIPDSDA 2922

Query: 2461 SFESLSPSSRPASPTRSQAQTPVLSPSLPDMSLSTHSSVQAGGWRKLPP-NLSPTIEYND 2519
            S  S S S  P    R++  T   + S         SS Q+ G+ + P  + SP++  ++
Sbjct: 2923 STASSSLSKSPEKNPRARMMTSTKAISA--------SSFQSTGFTETPEGSASPSMAGHE 2974

Query: 2520 GR-PAKRHDIARSHSESPSRLPINRSGTWKREHSKHSSSLPRVSTWR--RTGSSSSILSA 2576
             R P       R  SES S    +++ +     S  S      ST +  R+GSSSS +S 
Sbjct: 2975 PRVPTSGTGDPRYASESMSYPDPSKASSAMTSTSLASKLTTLFSTGQAARSGSSSSPISL 3034

Query: 2577 SSESSEKAKS---EDEKHVNSISGTKQSKENQV---------SAKGTWRKIKENEFSPTN 2624
            S+E      S      +  +   G   +++  +         +   T       E  P  
Sbjct: 3035 STEKETSFLSPTASTSRKTSLFLGPSMARQPNILVHLQTSALTLSPTSTLNMSQEEPPEL 3094

Query: 2625 STSQTVSSGATNGAESKTLIYQMAPAVSKTEDVWVRIEDCPINNPRSGRSPTGNTPPV-I 2683
            ++SQT++      AE++TL +   P+ + T  +       P+++P    +   ++P    
Sbjct: 3095 TSSQTIAEEEGTTAETQTLTF--TPSETPTSLL-------PVSSPTEPTARRKSSPETWA 3145

Query: 2684 DSVSEKANPNIKDSKD----------NQAKQNVGN--------GSVPMRTVGLENRLNSF 2725
             S+S  A  ++ ++ D          +QA Q            GS P  T      +++ 
Sbjct: 3146 SSISVPAKTSLVETTDGTLVTTIKMSSQAAQGNSTWPAPAEETGSSPAGTSPGSPEMSTT 3205

Query: 2726 IQVDAPDQKGTEIKPG-----QNNP-------VPVSETNESSIVERTPFSSSSSSKHSSP 2773
            +++ +   K   I P      +N+P       VP+  T E   ++ T   S S+S    P
Sbjct: 3206 LKIMS--SKEPSISPEIRSTVRNSPWKTPETTVPMETTVEPVTLQSTALGSGSTSISHLP 3263

Query: 2774 SGTVAARVTP---------FNYNPSPRKSSADSTSARP 2802
            +GT +   +P          + +PSP ++  +  S  P
Sbjct: 3264 TGTTSPTKSPTENMLATERVSLSPSPPEAWTNLYSGTP 3301



 Score = 43.5 bits (101), Expect = 0.003
 Identities = 143/657 (21%), Positives = 239/657 (36%), Gaps = 104/657 (15%)

Query: 2236 VRNSSSSTSP------VSKKGPPLKTPAS----KSPSEGQTATTSPRG-AKPSVKSE--L 2282
            V N  +++SP      VS    P K  ++     +  +   +T+ PR  A   ++SE   
Sbjct: 6303 VANVGTTSSPNEFYFTVSPDSDPYKATSAVVITSTSGDSIVSTSMPRSSAMKKIESETTF 6362

Query: 2283 SPVAR----QTSQIGGSSKAPSRSGSRDSTPSRPAQQPLSRP-IQSPGRNSISPGRNGIS 2337
            S + R     TSQ  GSS   S    +  T    A   +SR  + S  R SI        
Sbjct: 6363 SLIFRLRETSTSQKIGSSSDTSTVFDKAFTA---ATTEVSRTELTSSSRTSIQGTEKPTM 6419

Query: 2338 PPNKLSQLPRTSSPSTASTKSSGSGKMSYTSPGRQMSQQNLTKQTGLSKNASSIPRSESA 2397
             P+  ++     S     TKS      + T P R  SQ  LT  T ++   S      + 
Sbjct: 6420 SPDTSTRSVTMLSTFAGLTKSEERTIATQTGPHRATSQGTLTWDTSIT--TSQAGTHSAM 6477

Query: 2398 SKGLNQMNNGNGANKKVELSRMSSTKSSGSESDRSERPVLVRQSTFIKEAPSPTLRRKLE 2457
            + G +Q+          +LS ++S                 R   +I     P++  K  
Sbjct: 6478 THGFSQL----------DLSTLTS-----------------RVPEYISGTSPPSV-EKTS 6509

Query: 2458 ESASFESL----SPSSRPASPTRSQAQTPVLSPSLPDMSLSTHSSVQAGGWRKLPPNLSP 2513
             S+S  SL    SPS  P +   S+  +PV   SLP   L   + + A     LPPNL  
Sbjct: 6510 SSSSLLSLPAITSPSPVPTTLPESRPSSPVHLTSLPTSGLVKTTDMLA-SVASLPPNLGS 6568

Query: 2514 TIEYNDGRPAKRHDIARSHSESPS-RLPINRSGTWKREHSKHSS----------SLPRVS 2562
            T   +   P    DI  +    PS  + +   GT   E   +SS          + P V+
Sbjct: 6569 T---SHKIPTTSEDIKDTEKMYPSTNIAVTNVGTTTSEKESYSSVPAYSEPPKVTSPMVT 6625

Query: 2563 TWR-RTGSSSSILSASSESSEKAKSEDEKHVNSISGTKQSKENQVSAKGTWRKIKENEFS 2621
            ++  R    S+ +  SSE +           + + GT  S++  VS + +    K    +
Sbjct: 6626 SFNIRDTIVSTSMPGSSEITRIEMESTFSLAHGLKGTSTSQDPIVSTEKSAVLHKLTTGA 6685

Query: 2622 PTNSTSQTVSS------GATNGAESKTLIYQMAPAVSKTEDVWVRIEDCPINNPRSGRSP 2675
               S ++  SS      G  +  ES  +  ++ P++  +  +             S  + 
Sbjct: 6686 TETSRTEVASSRRTSIPGPDHSTESPDISTEVIPSLPISLGI----------TESSNMTI 6735

Query: 2676 TGNTPPVIDSVSEKANPNIKDSKDNQAKQNVGNGSVPMRTVGLENRLNSFIQVDAPDQKG 2735
               T P + S S+        +  ++A      G+  M T    +   + +    P+   
Sbjct: 6736 ITRTGPPLGSTSQGTFTLDTPTTSSRA------GTHSMATQEFPHSEMTTVMNKDPEILS 6789

Query: 2736 TEIKPGQNNPVPVSETNESSIVERTPFSSS-SSSKHSSPSGTVAARVTP--------FNY 2786
              I P        S    S  +   P SS+   + H++PS  + + +TP           
Sbjct: 6790 WTIPPSIEKTSFSSSLMPSPAMTSPPVSSTLPKTIHTTPS-PMTSLLTPSLVMTTDTLGT 6848

Query: 2787 NPSPRKSSADSTSARPSQIPTPVNNNTKKRDSKTDSTESSGTQSPKRHSGSYLVTSV 2843
            +P P  SS  + S+   +I T  + +T   ++   ST ++ T      SG    +SV
Sbjct: 6849 SPEPTTSSPPNLSSTSHEILT-TDEDTTAIEAMHPSTSTAATNVETTSSGHGSQSSV 6904



 Score = 43.1 bits (100), Expect = 0.004
 Identities = 173/845 (20%), Positives = 303/845 (35%), Gaps = 133/845 (15%)

Query: 2074 EDLTLDLKDIQRPDSEHGLSPDSENFDWKAIQEGANSIVSSLHQAAAAACL-------SR 2126
            E +T   +++  P +E  L+  +   D + I    N  V+++  A++A  L       S 
Sbjct: 4502 EPVTNSPQNLNNPSNEI-LATLAATTDIETIHPSINKAVTNMGTASSAHVLHSTLPVSSE 4560

Query: 2127 QASSDSDSILSLKSGISLGS---PFHLTPDQEEKPFTSNKGPRILKPGEKSTLETKKIES 2183
             +++ S  + +   G +L S   P   T D E +P +S    R     E STL+     +
Sbjct: 4561 PSTATSPMVPASSMGDALASISIPGSETTDIEGEPTSSLTAGR----KENSTLQEMNSTT 4616

Query: 2184 ESKGIKGGKKVYKSLITGKVRSNSEISGQMKQPLQA----NMPSISRGRTMIHIPGVRNS 2239
            ES  I     V       K+   S  +  +  P Q+    ++ S++  R     P   ++
Sbjct: 4617 ESNIILSNVSVGAITEATKMEVPSFDATFIPTPAQSTKFPDIFSVASSRLSNSPPMTIST 4676

Query: 2240 SSSTSPVSKKGPPLKTPASKSPSEGQTATTSPRGAKPSVKSELSPVARQTSQIGGSSKAP 2299
              +T+     G       SK P    T+T       PSV +E    ++ T+ +    K  
Sbjct: 4677 HMTTTQTGSSGA-----TSKIPLALDTSTLETSAGTPSVVTEGFAHSKITTAMNNDVKDV 4731

Query: 2300 SRSGS--RDSTPSRPAQQPLSRPIQSPGRNSISPGRNGISPPNKLSQLPRTSSPSTASTK 2357
            S++    +D   S  +Q P+      P   + +P  +  S P  +S +  +S   TA   
Sbjct: 4732 SQTNPPFQDEASSPSSQAPVL-VTTLPSSVAFTPQWHSTSSPVSMSSVLTSSLVKTA--- 4787

Query: 2358 SSGSGKMSYTSPGRQMSQQNLTKQTGLSKNASSIPRSESASKGLNQMNNGNGANKKVELS 2417
                GK+                 T L    SS    +S S  L+ ++  + A   +E +
Sbjct: 4788 ----GKVD----------------TSLETVTSS---PQSMSNTLDDISVTSAATTDIETT 4824

Query: 2418 RMSSTK---SSGSESDRSERPVLVRQSTFIKEAPSPTLRRKLEESASFESLSPSSRPASP 2474
              S      + G+     E    V       +  SP +     E  +     P S   + 
Sbjct: 4825 HPSINTVVTNVGTTGSAFESHSTVSAYPEPSKVTSPNVTTSTMEDTTISRSIPKSSKTTR 4884

Query: 2475 TRSQAQTPVLSPSLPDMSLSTHSSVQAGGWRKLPPNLSPTIEYNDGRPA----KRHDIAR 2530
            T ++  T  L+P L + S+S   +             + T+ Y +   A     R D+  
Sbjct: 4885 TETET-TSSLTPKLRETSISQEITSSTE---------TSTVPYKELTGATTEVSRTDVTS 4934

Query: 2531 SHSESPSRLPINRSGTWKREHSKHSSSLPRVSTWRRTGSSSSILSASSESSEKAKSEDEK 2590
            S S S    P     T   + S  +++  R+ST      S+ I   +      A S+D  
Sbjct: 4935 SSSTS---FPGPDQSTVSLDISTETNT--RLSTSPIMTESAEITITTQTGPHGATSQDTF 4989

Query: 2591 HVNSISGTKQSKENQVSAKG--------TWRKIKEN-------EFSPTNSTSQTVSSGA- 2634
             ++  + T Q+  +     G           +I ++           T+S S  +SS A 
Sbjct: 4990 TMDPSNTTPQAGIHSAMTHGFSQLDVTTLMSRIPQDVSWTSPPSVDKTSSPSSFLSSPAM 5049

Query: 2635 -TNGAESKTLIYQM--APAVSKTEDVWVRIEDCPINNPRSGRSPTGNTPPVIDSVSEKAN 2691
             T    S TL      +P  S      V+I D      R+   P  ++ P   S S+K  
Sbjct: 5050 TTPSLISSTLPEDKLSSPMTSLLTSGLVKITDIL----RTRLEPVTSSLPNFSSTSDKIL 5105

Query: 2692 PNIKDSKDNQ---AKQNVGNGSVPMRTVGLENRLNSFIQVDAPDQKGTEI------KPGQ 2742
               KDSKD +      N    +V     G E+   +    + P      +       P  
Sbjct: 5106 ATSKDSKDTKEIFPSINTEETNVKANNSGHESHSPALADSETPKATTQMVITTTVGDPAP 5165

Query: 2743 NNPVPVSETNESSIVERTP-------FSSSSSSKHSS------------PSGTVAARVTP 2783
            +  +PV  ++E++ ++R P          +S+S+ SS            P+GT+   V+ 
Sbjct: 5166 STSMPVHGSSETTNIKREPTYFLTPRLRETSTSQESSFPTDTSFLLSKVPTGTI-TEVSS 5224

Query: 2784 FNYNPSPRKSSADSTSAR------PSQIPTPVNNNTKKRDSKTDSTESSGTQSPKRHSGS 2837
               N S + S+ D   +         +IP    ++ K + ++   T  +       HS  
Sbjct: 5225 TGVNSSSKISTPDHDKSTVPPDTFTGEIPRVFTSSIKTKSAEMTITTQASPPESASHSTL 5284

Query: 2838 YLVTS 2842
             L TS
Sbjct: 5285 PLDTS 5289



 Score = 42.4 bits (98), Expect = 0.007
 Identities = 140/690 (20%), Positives = 258/690 (37%), Gaps = 127/690 (18%)

Query: 2216 PLQANMPSISRGRTMIHIPGVRNSSSSTSPVSKKGPPLKTPASKSPSEGQTATTSPRGAK 2275
            P+   +P  SR  + +H+     +S  TS + K    L + AS  P+ G T+   P  ++
Sbjct: 6525 PVPTTLPE-SRPSSPVHL-----TSLPTSGLVKTTDMLASVASLPPNLGSTSHKIPTTSE 6578

Query: 2276 ---------PSVKSELSPVARQTSQIGGSSKAPSRS-------------GSRDS--TPSR 2311
                     PS    ++ V   TS+    S  P+ S               RD+  + S 
Sbjct: 6579 DIKDTEKMYPSTNIAVTNVGTTTSEKESYSSVPAYSEPPKVTSPMVTSFNIRDTIVSTSM 6638

Query: 2312 PAQQPLSRPIQSPGRNSISPGRNGISPPN-------KLSQLPR--TSSPSTASTKSSGSG 2362
            P    ++R I+     S++ G  G S          K + L +  T +  T+ T+ + S 
Sbjct: 6639 PGSSEITR-IEMESTFSLAHGLKGTSTSQDPIVSTEKSAVLHKLTTGATETSRTEVASSR 6697

Query: 2363 KMSYTSPGRQMSQQNLTKQTGLSKNASSIPRSESASKGLNQMNN---GNGANKKVELSRM 2419
            + S   P       +++ +  +     S+  +ES++  +        G+ +     L   
Sbjct: 6698 RTSIPGPDHSTESPDISTEV-IPSLPISLGITESSNMTIITRTGPPLGSTSQGTFTLDTP 6756

Query: 2420 SSTKSSGSESDRSERPVLVRQSTFIKEAP---SPTLRRKLEESASFESLSPSSRPASP-- 2474
            +++  +G+ S  ++       +T + + P   S T+   +E+++   SL PS    SP  
Sbjct: 6757 TTSSRAGTHSMATQEFPHSEMTTVMNKDPEILSWTIPPSIEKTSFSSSLMPSPAMTSPPV 6816

Query: 2475 ---------TRSQAQTPVLSPSLPDMSLSTHSSVQAGGWRKLPPNLSPTIEYNDGRPAKR 2525
                     T     T +L+PSL   + +  +S +       PPNLS T           
Sbjct: 6817 SSTLPKTIHTTPSPMTSLLTPSLVMTTDTLGTSPEPT--TSSPPNLSST----------S 6864

Query: 2526 HDIARSHSESPSRLPINRSGTWKREHSKHSSSLPRVSTWRRTGSSSSILSASSESSEKAK 2585
            H+I  +  ++ +   ++ S +    + + +SS          GS SS+L+     SEK K
Sbjct: 6865 HEILTTDEDTTAIEAMHPSTSTAATNVETTSS--------GHGSQSSVLA----DSEKTK 6912

Query: 2586 SEDEKHVNSISG-TKQSKENQVSAKGTWRKIKENEFSPTNSTSQTVSSGATNGAESKTLI 2644
            +       S  G T  S    VS++ T  K +E+ +S T    +T  S   + +   +++
Sbjct: 6913 ATAPMDTTSTMGHTTVSTSMSVSSETTKIK-RESTYSLTPGLRETSISQNASFSTDTSIV 6971

Query: 2645 YQMAPAVSKTEDVWVRIEDCPINNPRSGRS--PTGNTPPVIDSVSEK------ANPNIKD 2696
                P  +  E     +         SGR+  P  +   V+  +S +      A+P + +
Sbjct: 6972 LSEVPTGTTAEVSRTEVTS-------SGRTSIPGPSQSTVLPEISTRTMTRLFASPTMTE 7024

Query: 2697 SKDNQAKQNVG-NGSVPMRTVGLENRLNSFIQVDAPDQKGTEIKPGQNNPVPVSETNESS 2755
            S +       G +GS    T+ L+                        +         S+
Sbjct: 7025 SAEMTIPTQTGPSGSTSQDTLTLD-----------------------TSTTKSQAKTHST 7061

Query: 2756 IVERTPFSSSSSSKHSSPSGTVAARVTPFNYNPSPRKSSAD---STSARPSQIPTPVNNN 2812
            + +R P S  ++     P G ++ + +P   NPS   S      +TS  P     PV  +
Sbjct: 7062 LTQRFPHSEMTTLMSRGP-GDMSWQSSPSLENPSSLPSLLSLPATTSPPPISSTLPVTIS 7120

Query: 2813 TKKRDSKTDSTESSGTQSPKRHSGSYLVTS 2842
            +      +  T S  T +   H+   LVTS
Sbjct: 7121 SSPLPVTSLLTSSPVTTTDMLHTSPELVTS 7150



 Score = 41.2 bits (95), Expect = 0.015
 Identities = 142/690 (20%), Positives = 256/690 (37%), Gaps = 94/690 (13%)

Query: 2197 SLITGKVRSNSEISGQ-MKQPLQANMPSISRGRTMIH--IP---GVRNSSSSTSPVSKKG 2250
            S++  K+   S  SGQ +  PL   +P  +R  TM +  IP    + N+ +S   V    
Sbjct: 289  SVLDNKISETSIFSGQSLTSPLSPGVPE-ARASTMPNSAIPFSMTLSNAETSAERVRSTI 347

Query: 2251 PPLKTPASKSPSEGQTATTSPRGAK----PSV---KSELSPVARQTSQIGGSSKAPSRSG 2303
              L TP+  +    +T  T    A+    PS    K+  S        +GG+S +   + 
Sbjct: 348  SSLGTPSISTKQTAETILTFHAFAETMDIPSTHIAKTLASEWLGSPGTLGGTSTSALTTT 407

Query: 2304 SRDST----PSRPAQQPLSRPIQSPGRNSISPGRNGISPPNKLSQLPRTSSPS----TAS 2355
            S  +T     +        +  +     S++P     S P + S++  T  P+    T  
Sbjct: 408  SPSTTLVSEETNTHHSTSGKETEGTLNTSMTPLET--SAPGEESEMTATLVPTLGFTTLD 465

Query: 2356 TKSSGSGKMSYTSPGRQMSQQNLTKQTGLSKNA----SSIPRSESASKGLNQMNNGNGAN 2411
            +K     ++S + P R++     T     S  A    S I R+ ++S   ++ ++    +
Sbjct: 466  SKIRSPSQVSSSHPTRELRTTGSTSGRQSSSTAAHGSSDILRATTSST--SKASSWTSES 523

Query: 2412 KKVELSRMSSTK-SSGSESDRSERPVLVRQ-------------STFIKEAPSPTLRRKLE 2457
               + S    T+    S S ++ERP                  S F     S T    LE
Sbjct: 524  TAQQFSEPQHTQWVETSPSMKTERPPASTSVAAPITTSVPSVVSGFTTLKTSSTKGIWLE 583

Query: 2458 ESASFESLSPSSRPASPTRSQAQTPVLSPSLPDMSLSTHSSVQAG-GWRKLPPNLSPTIE 2516
            E+++   +  S+  A PT  Q   P        +S++  SS +   G   L    + + E
Sbjct: 584  ETSADTLIGEST--AGPTTHQFAVPT------GISMTGGSSTRGSQGTTHLLTRATASSE 635

Query: 2517 YNDGRPAKRHDIARSHSESPSRLPINRS--GTWKREHSKHSSSLPRVSTWR----RTGSS 2570
             +       + +  S S + S+     S  G  K  ++  SS +P  S+ +    R G+S
Sbjct: 636  TSADLTLATNGVPVSVSPAVSKTAAGSSPPGGTKPSYTMVSSVIPETSSLQSSAFREGTS 695

Query: 2571 SSILSASSESSEKAKSEDEKHVNSIS------GTKQSKENQVSAKGTWRKIKENEFSPTN 2624
              +   ++     +   D      IS       +    E++VSA  T+   K      T+
Sbjct: 696  LGLTPLNTRHPFSSPEPDSAGHTKISTSIPLLSSASVLEDKVSATSTFSHHKA-----TS 750

Query: 2625 STSQTVSSGATNGAESKTLIYQMAPAVSKTEDVWVRIEDCPINNPR-SGRSPTGNTPPVI 2683
            S +      +T    S  ++  M  + + T    VR    P+ +P  SG    G+   + 
Sbjct: 751  SITTGTPEISTKTKPSSAVLSSMTLSNAATSPERVRNATSPLTHPSPSGEETAGSVLTLS 810

Query: 2684 DSVSEKANPNIKDSKDNQAKQNVGNGSVPMRTV-GLENRLNSFIQVDAPDQKGTEIKPGQ 2742
             S     +PNI  +    ++ +    ++ + +V G++   +S          G E +   
Sbjct: 811  TSAETTDSPNIHPTGTLTSESSESPSTLSLPSVSGVKTTFSSSTPSTHLFTSGEETEETS 870

Query: 2743 NNPVPVSETNESSIVERTPFSSSSSSKHSSPSGTVAARVTPFNYNPSPRKSSADSTSARP 2802
            N  V   ET+ S +  RT  +S+S                     P+P   + D+   R 
Sbjct: 871  NPSVSQPETSVSRV--RTTLASTSV--------------------PTPVFPTMDTWPTRS 908

Query: 2803 SQIPTPVNNNTKKRDSKTDSTESSGTQSPK 2832
            +Q  +    +  +  S T  T S+G+  PK
Sbjct: 909  AQFSSSHLVSELRATSSTSVTNSTGSALPK 938



 Score = 40.0 bits (92), Expect = 0.033
 Identities = 143/698 (20%), Positives = 249/698 (35%), Gaps = 106/698 (15%)

Query: 2167 ILKPGEKSTLETKKIESESKGIKGGKKVYKSLITGKVRSNSEISGQMKQPLQANMPSISR 2226
            ++KPG  + L    IE+           +  + T ++  +S  S +M  P + N  S   
Sbjct: 1272 VVKPGSYTPLTFPSIET-----------HIHVSTARMAYSSGSSPEMTAPGETNTGSTWD 1320

Query: 2227 GRTMIHIPGVRNSSSSTSPVSKKGPPLKTPASKSPSEGQTA---------TTSPRGAKPS 2277
              T I     +++SS+          L+T  +   +E  T          ++SP    P+
Sbjct: 1321 PTTYITTTDPKDTSSAQVSTPHSVRTLRTTENHPKTESATPAAYSGSPKISSSPNLTSPA 1380

Query: 2278 VKS-ELSPVARQTSQIGGSSKAPSRSGSRDSTPSRPAQQ--PLSRPIQSPGRNSIS--PG 2332
             K+  ++     ++Q+  +  A   SG    +   P     P S  I S      S  PG
Sbjct: 1381 TKAWTITDTTEHSTQLHYTKLAEKSSGFETQSAPGPVSVVIPTSPTIGSSTLELTSDVPG 1440

Query: 2333 RNGISPPNKLSQ--LPRTSSPSTASTKSSGSGKMSYTSPGRQMSQQNL-----TKQTGLS 2385
               +  P++ +   LP  +  ST+ T+   S  +  +SP   MS   +     T    LS
Sbjct: 1441 EPLVLAPSEQTTITLPMATWLSTSLTEEMASTDLDISSPSSPMSTFAIFPPMSTPSHELS 1500

Query: 2386 KN---ASSIPRSESASK----GLNQMNNGNGANKKVELSRMSSTKSSGSESDRSERPVL- 2437
            K+    S+I  ++S +     G+  +    G    V ++ +++T +S  E     +  L 
Sbjct: 1501 KSEADTSAIRNTDSTTLDQHLGIRSLGR-TGDLTTVPITPLTTTWTSVIEHSTQAQDTLS 1559

Query: 2438 -----------VRQSTFIKEAPSPTLRRKLEESASFESLSPSS-----RPASPTRSQA-- 2479
                       ++  T I  + SP+   ++      +  S S      +P++ T S+   
Sbjct: 1560 ATMSPTHVTQSLKDQTSIPASASPSHLTEVYPELGTQGRSSSEATTFWKPSTDTLSREIE 1619

Query: 2480 QTPVLSPSLPDMSLSTHSSVQAG---GWRKLPPNLSPTIEYNDGRPAKRHDIA------- 2529
              P    S P M  +T  S  +G   G   LP   S   E +     +R           
Sbjct: 1620 TGPTNIQSTPPMDNTTTGSSSSGVTLGIAHLPIGTSSPAETSTNMALERRSSTATVSMAG 1679

Query: 2530 -----------RSHSESPSRLP--INRSGTWKREHSKHSSSLPRVSTWRRTGSSSSILSA 2576
                       RS S+S  R+   ++ S T     S   SS PR++T   T  SSS+  +
Sbjct: 1680 TMGLLVTSAPGRSISQSLGRVSSVLSESTTEGVTDSSKGSS-PRLNTQGNTALSSSLEPS 1738

Query: 2577 SSESSEKAKSEDEKHVNSISGTKQSKENQVSAKGTWRKIKENEFSPTNSTSQTVSSGATN 2636
             +E S+ + S     +   S         +     W K        T  TS    S A  
Sbjct: 1739 YAEGSQMSTS-----IPLTSSPTTPDVEFIGGSTFWTK-----EVTTVMTSDISKSSART 1788

Query: 2637 GAESKTLIYQMAPAVSKTEDVWVRIEDCPINNPRSGRSPTGNTPPVIDSVSEKANPNIKD 2696
             + S TL+     +   T    +R     + +P    +P+    P I      A PN  D
Sbjct: 1789 ESSSATLMSTALGSTENTGKEKLRTASMDLPSP----TPSMEVTPWISLTLSNA-PNTTD 1843

Query: 2697 SKDNQAKQNVGNGSVPMRTVGLENRLNSFIQVDAPDQKGTEIKPGQNNPVPVSETNESSI 2756
            S D     +  +      T+  +  LN+ +   +  + G++     +  + +  +  +S+
Sbjct: 1844 SLDLSHGVHTSSAG----TLATDRSLNTGVTRASRLENGSDT---SSKSLSMGNSTHTSM 1896

Query: 2757 VERTPFSSSSSSKHSSPSGTVAARVTPFNYNPSPRKSS 2794
               T  S  SSS H  P  +     T     P  R  S
Sbjct: 1897 T-YTEKSEVSSSIHPRPETSAPGAETTLTSTPGNRAIS 1933



 Score = 40.0 bits (92), Expect = 0.033
 Identities = 72/347 (20%), Positives = 132/347 (38%), Gaps = 51/347 (14%)

Query: 1194 SFSFSKSSSGQSSKTEHMSSSSENTSTPSSNAKRQNQLHPSSAQ---------------- 1237
            + + S++S+G +   + +S+   +    +     ++ LHPSS                  
Sbjct: 2685 TLTMSETSNGDALVLKTVSNPDRSIPGITIQGVTESPLHPSSTSPSKIVAPRNTTYEGSI 2744

Query: 1238 --SRSGQPQKAATCKVSSINQETIQTYCVEDTPICFSRCSSLSSLSSAEDEI---GCNQT 1292
              + S  P       V S + E  +T  + D+     R S +   + ++      G    
Sbjct: 2745 TVALSTLPAGTTGSLVFSQSSENSETTALVDSSAGLERASVMPLTTGSQGMASSGGIRSG 2804

Query: 1293 TQEADSANTLQIAEIKEKIGTRSAEDPVSEVPAVSQHPRTKSSRLQGSSLSSESARHKAV 1352
            +  +    T     +    G  +A   +SE+   ++   T+S+  +G  +   SA    +
Sbjct: 2805 STHSTGTKTFSSLPLTMNPGEVTA---MSEI-TTNRLTATQSTAPKGIPVKPTSAESGLL 2860

Query: 1353 EFSSGAKSPSKSGAQTPKSPPEHYVQETPLMFSRCTSVSSLDSFESRSIASSVQSEPCSG 1412
               S + SPSK+ A    +PP   + ++ L F   + V SLD+ +S S+ +  Q      
Sbjct: 2861 TPVSASSSPSKAFASLTTAPPTWGIPQSTLTF-EFSEVPSLDT-KSASLPTPGQ------ 2912

Query: 1413 MVSGIISPSDLPDSPGQTMPPSRSKTPPPPPQTAQTKREVPKNKAPTAEKRES------- 1465
                  S + +PDS   T   S SK+P   P+     R +   KA +A   +S       
Sbjct: 2913 ------SLNTIPDSDASTASSSLSKSPEKNPRA----RMMTSTKAISASSFQSTGFTETP 2962

Query: 1466 -GPKQAAVNAAVQRVQVLPDADTLLHFATESTPDGFSCSSSLSALSL 1511
             G    ++     RV      D      + S PD    SS++++ SL
Sbjct: 2963 EGSASPSMAGHEPRVPTSGTGDPRYASESMSYPDPSKASSAMTSTSL 3009



 Score = 39.7 bits (91), Expect = 0.043
 Identities = 132/657 (20%), Positives = 251/657 (38%), Gaps = 91/657 (13%)

Query: 2236 VRNSSSSTSPVSKKGPPLKTPASKSPSEGQTAT----TSP-------RGAKPSVKSELSP 2284
            + +++ +TS VS         +  +PS G+T++    TSP       R    +VKS+++P
Sbjct: 3452 ITSTAQTTSLVSLPSGDQGITSLTNPSGGKTSSASSVTSPSIGLETLRANVSAVKSDIAP 3511

Query: 2285 VARQTSQIGGSSKAPSRSGSRDSTPSRPAQQPLSRPIQSPGRNSISPGRNGISPPNKLSQ 2344
             A   SQ    ++      +   TP       +S  I + G NSIS      +P   +S 
Sbjct: 3512 TAGHLSQTSSPAEVSILDVTTAPTPG------ISTTITTMGTNSIS--TTTPNPEVGMST 3563

Query: 2345 LPRTSSPSTASTKSSGSGKMSYTSPGRQMSQQNLTKQTGLSKNASSIPRSE-----SASK 2399
            +  T +    +T +      S T+     +  ++T    ++++  +I         ++S 
Sbjct: 3564 MDSTPATERRTTSTEHPSTWSSTAASDSWTVTDMTSNLKVARSPGTISTMHTTSFLASST 3623

Query: 2400 GLNQMNNGNGANKKVELSRMSSTKSSG---SESDRSERPVLVRQSTFIKEAPSPTLRRKL 2456
             L+ M+  +G    +  S ++ +  +    +E+  SER +    +T     P  T  R  
Sbjct: 3624 ELDSMSTPHGRITVIGTSLVTPSSDASAVKTETSTSERTLSPSDTT--ASTPISTFSRVQ 3681

Query: 2457 EESASFESLSPSSRPASPTRSQAQTPVLSPSLPDMSLSTHSSVQAGGWRKLPPNLSPTIE 2516
              S S   +  +S   S T ++   PV   S    S  T  +     +  L  +LS T++
Sbjct: 3682 RMSISVPDILSTSWTPSSTEAE-DVPVSMVSTDHASTKTDPNTPLSTF--LFDSLS-TLD 3737

Query: 2517 YNDGRPAKRHDIARSHSESPSRLPINRSGTWKREHSKHSSSLP--------RVSTWRRTG 2568
            ++ GR       A + + +P      +  T +   S  +S LP         V+      
Sbjct: 3738 WDTGRSLSS---ATATTSAPQGATTPQELTLETMISPATSQLPFSIGHITSAVTPAAMAR 3794

Query: 2569 SSSSILSASSESSEKAKSEDEKHVNSISG----TKQSKENQVSAKGTWRKIKENEFSPTN 2624
            SS    S    +S+KA+    +   + S       +S    +       K  +  F    
Sbjct: 3795 SSGVTFSRPDPTSKKAEQTSTQLPTTTSAHPGQVPRSAATTLDVIPHTAKTPDATFQRQG 3854

Query: 2625 STSQTVSSGATNGAESKTLIYQMAPAVSKTEDVWVRIEDCPINNPRSGRS--PTGNTPPV 2682
             T+ T  + AT+ + ++    +  P+     ++   + +  I    S  S   T NT  +
Sbjct: 3855 QTALTTEARATSDSWNEK--EKSTPSAPWITEMMNSVSEDTIKEVTSSSSVLRTLNTLDI 3912

Query: 2683 ------IDSVSEKANP--NIKDSKDNQAKQNVGNGSVPMRTVG----LENRLNSFIQVDA 2730
                    S S K++P   I  S+    K+ +   +  + T G     E+  +S I   +
Sbjct: 3913 NLESGTTSSPSWKSSPYERIAPSESTTDKEAIHPSTNTVETTGWVTSSEHASHSTIPAHS 3972

Query: 2731 PDQKGTEIKPGQNNPVPVSETNESSIVERTPFSSSSSSK-HSSPSG--TVAAR-VTPFNY 2786
               K T       +PV  + T E +IV  +  +   S++  + P+   T+  R V+P+  
Sbjct: 3973 ASSKLT-------SPVVTTSTREQAIVSMSTTTWPESTRARTEPNSFLTIELRDVSPY-- 4023

Query: 2787 NPSPRKSSADSTSARPSQIPTPVNNNTKKRDSKTDSTESSGTQSPKRHSGSYLVTSV 2843
                     D++S   + I +   +    +  +T+ T S      KR S S+L  S+
Sbjct: 4024 --------MDTSSTTQTSIISSPGSTAITKGPRTEITSS------KRISSSFLAQSM 4066



 Score = 39.3 bits (90), Expect = 0.056
 Identities = 142/708 (20%), Positives = 253/708 (35%), Gaps = 104/708 (14%)

Query: 2151 TPDQEEKPFTSNKGPRILKPGEKSTLETKKIESESKGIKGGKKVYK----------SLIT 2200
            T + +   FT ++ P  L P    T  T + +S  +       V            +L+T
Sbjct: 3107 TAETQTLTFTPSETPTSLLPVSSPTEPTARRKSSPETWASSISVPAKTSLVETTDGTLVT 3166

Query: 2201 GKVRSNSEISGQMKQPLQANMPSISRGRTMIHIPGVRNSSSSTSPVSKKGPPLKTPASKS 2260
                S+    G    P  A     S   T    PG    S++   +S K P +      S
Sbjct: 3167 TIKMSSQAAQGNSTWPAPAEETGSSPAGTS---PGSPEMSTTLKIMSSKEPSI------S 3217

Query: 2261 PSEGQTATTSPRGAKPS---VKSELSPVARQTSQIGGSSKAPSRSGSRDSTPSRPAQQPL 2317
            P    T   SP     +   +++ + PV  Q++ +G  S + S   +  ++P++      
Sbjct: 3218 PEIRSTVRNSPWKTPETTVPMETTVEPVTLQSTALGSGSTSISHLPTGTTSPTK------ 3271

Query: 2318 SRPIQSPGRNSISPGRNGISPP------NKLSQLP---RTSSPSTASTKSSGSGKMSYTS 2368
                 SP  N ++  R  +SP       N  S  P   R S  + +S         S T 
Sbjct: 3272 -----SPTENMLATERVSLSPSPPEAWTNLYSGTPGGTRQSLATMSSVSLESPTARSITG 3326

Query: 2369 PGRQMSQQNLTKQTGL-----------SKNASSIPRSESASKGLNQMNNGNGANKKVELS 2417
             G+Q S + ++K TG+           +   + +  S S++   + + + N  +   + S
Sbjct: 3327 TGQQSSPELVSKTTGMEFSMWHGSTGGTTGDTHVSLSTSSNILEDPVTSPNSVSSLTDKS 3386

Query: 2418 R------MSSTKSSGSESDRSERPVLVRQSTFIKEAPSPTLRRKLEESASFESL--SPSS 2469
            +      +S+T    +  +        + S  + EA S T     + S S  +L  SP  
Sbjct: 3387 KHKTETWVSTTAIPSTVLNNKIMAAEQQTSRSVDEAYSSTSSWSDQTSGSDITLGASPDV 3446

Query: 2470 RPASPTRSQAQTPVLSPSLP--DMSLSTHSSVQAGGWRKLPPNLSPTIEYNDGRPAKRHD 2527
                   S AQT  L  SLP  D  +++ ++   G         SP+I    G    R +
Sbjct: 3447 TNTLYITSTAQTTSL-VSLPSGDQGITSLTNPSGGKTSSASSVTSPSI----GLETLRAN 3501

Query: 2528 IARSHSE-SPSRLPINRSGTWKREHSKHSSSLPRVSTWRRTGSSSSILSASSESSEKAKS 2586
            ++   S+ +P+      +G   +  S    S+  V+T    G S++I +  + S      
Sbjct: 3502 VSAVKSDIAPT------AGHLSQTSSPAEVSILDVTTAPTPGISTTITTMGTNSISTTTP 3555

Query: 2587 EDEKHVNSISGTKQSKENQVSAK--GTWRKIKENEFSPTNSTSQTVSSGATN--GAESKT 2642
              E  ++++  T  ++    S +   TW        S   S S TV+   +N   A S  
Sbjct: 3556 NPEVGMSTMDSTPATERRTTSTEHPSTWS-------STAASDSWTVTDMTSNLKVARSPG 3608

Query: 2643 LIYQMAPAVSKTEDVWVRIEDCPINNPRSGRSPTGNTPPVIDSVSEKANPNIKDSKDNQA 2702
             I  M      T        +    +   GR     T  V  S    A      + +   
Sbjct: 3609 TISTM-----HTTSFLASSTELDSMSTPHGRITVIGTSLVTPSSDASAVKTETSTSERTL 3663

Query: 2703 KQNVGNGSVPMRTVGLENRLNSFIQVDAPDQKGTEIKPG--QNNPVPVSETNESSIVERT 2760
              +    S P+ T     R++    +  PD   T   P   +   VPVS  +       T
Sbjct: 3664 SPSDTTASTPISTFSRVQRMS----ISVPDILSTSWTPSSTEAEDVPVSMVS-------T 3712

Query: 2761 PFSSSSSSKHSSPSGTVAARVTPFNYNPSPRKSSADSTSARPSQIPTP 2808
              +S+ +  ++  S  +   ++  +++     SSA +T++ P    TP
Sbjct: 3713 DHASTKTDPNTPLSTFLFDSLSTLDWDTGRSLSSATATTSAPQGATTP 3760



 Score = 38.9 bits (89), Expect = 0.073
 Identities = 141/714 (19%), Positives = 257/714 (35%), Gaps = 105/714 (14%)

Query: 2124 LSRQASSDSDSILSLKSGISLGSPFHLTPDQEEKPFTSNK---GPRILKPGEKSTLETKK 2180
            ++R +  ++ S  S KS +S+G+  H +    EK   S+     P    PG ++TL +  
Sbjct: 1869 VTRASRLENGSDTSSKS-LSMGNSTHTSMTYTEKSEVSSSIHPRPETSAPGAETTLTSTP 1927

Query: 2181 IESESKGIKGGKKVYKSLITGKVRSNSEISGQMKQPLQANMPSISRGRTMIHIPGVRNSS 2240
                     G + +  +L    +     IS  +      N         M H P    + 
Sbjct: 1928 ---------GNRAISLTLPFSSIPVEEVISTGITSGPDIN------SAPMTHSPITPPTI 1972

Query: 2241 --SSTSPVSKKGPPLKTPASKSPSEGQTATTSPRGAKPSVKSELSPVARQTSQIGGSSKA 2298
              +ST  + +   PL   +S+  S    +T        SV    SP    +   G S+ +
Sbjct: 1973 VWTSTGTIEQSTQPLHAVSSEKVSVQTQSTPYVN----SVAVSASPTHENSVSSGSSTSS 2028

Query: 2299 PSRSGSRDSTPSRPAQQPLSRPIQSPGRNSISPGRNGISPPNKLSQLPRTSSPSTASTKS 2358
            P  S S +S  S      +SR      RN+I+     ++     + LP T+ PST+ +++
Sbjct: 2029 PYSSASLESLDST-----ISR------RNAITSWLWDLT-----TSLPTTTWPSTSLSEA 2072

Query: 2359 SGSGKMSYTSPGRQMSQQNLTKQTGLSKNASSIPRSESASKGLNQMNNGNGANKKVELSR 2418
              SG    ++P       + T +  L   AS+     SA+K  N     +G       + 
Sbjct: 2073 LSSGHSGVSNP------SSTTTEFPLFSAAST-----SAAKQRNPETETHGPQ---NTAA 2118

Query: 2419 MSSTKSSGSESDRSERPVLVRQSTFIKEAPSPTLRRKLEESASFESLSPSSRPASPTRSQ 2478
             +    + S +  SE PV    ++   E P P       + +   S S ++ P+  T S 
Sbjct: 2119 STLNTDASSVTGLSETPV---GASISSEVPLPMAITSRSDVSGLTSES-TANPSLGTASS 2174

Query: 2479 AQTPVL-SPSLPDMSLSTHSSVQAGGWRKLPP-------NLSPTIEYNDGRPAKRHDIAR 2530
            A T +  + SLP         +    W    P       N   +I  N   P     +A 
Sbjct: 2175 AGTKLTRTISLPTSESLVSFRMNKDPWTVSIPLGSHPTTNTETSIPVNSAGPPGLSTVAS 2234

Query: 2531 SHSESPSRLPINRSGTWKREHSKHSSSLPRVSTWRRTGSSSSILSASSESSEKAKSEDEK 2590
               ++P               S  + S+P VS    + S  + ++  S   EK  +   +
Sbjct: 2235 DVIDTP---------------SDGAESIPTVSF---SPSPDTEVTTISHFPEKT-THSFR 2275

Query: 2591 HVNSISGTKQSKENQVSAKGTWRKIKENEFSPTNSTSQTVSSGATNGAESKTLIYQMAPA 2650
             ++S++    S+   +   G W        S   ST  T +S +    E +T+      A
Sbjct: 2276 TISSLTHELTSRVTPI--PGDW-------MSSAMSTKPTGASPSITLGERRTI----TSA 2322

Query: 2651 VSKTEDVWVRIEDCPINNPRSGRSPTGNTPPVIDSVSEKANPNIKDSKDNQAKQNVGNGS 2710
               T  + +       +        T  T  ++D+      P+   S  +    ++ + +
Sbjct: 2323 APTTSPIVLTASFTETSTVSLDNETTVKTSDILDARKTNELPSDSSSSSDLINTSIASST 2382

Query: 2711 VPM-RTVGLENRLNSFIQVDAPDQKGTEIKPGQNNPVPVSETNESSIVERTPFSSSSSSK 2769
            + + +T  +     S +   +     +  +P     VP S T  ++    +  S++ S  
Sbjct: 2383 MDVTKTASISPTSISGMTASSSPSLFSSDRP----QVPTSTTETNTATSPSVSSNTYSLD 2438

Query: 2770 HSSPSGTVAARVTPFNYNPSPRKSSADSTSARPSQ-IPTPVNNNTKKRDSKTDS 2822
              S  G   + + PF        SSA    +RP +   T V+ +T   ++ T S
Sbjct: 2439 GGSNVGGTPSTLPPFTITHPVETSSALLAWSRPVRTFSTMVSTDTASGENPTSS 2492



 Score = 38.1 bits (87), Expect = 0.12
 Identities = 113/567 (19%), Positives = 198/567 (34%), Gaps = 88/567 (15%)

Query: 2222 PSISRGRTMIHIPGVRNSSSSTSPVSKKGPPLKTPASKSPSEGQTATTSPRGAKPSVKSE 2281
            P+  R  T    P   +S++++   +          ++SP    T  T+   A  +    
Sbjct: 3568 PATERRTTSTEHPSTWSSTAASDSWTVTDMTSNLKVARSPGTISTMHTTSFLASSTELDS 3627

Query: 2282 LSPVARQTSQIGGSSKAPSRSGSRDSTPSRPAQQPLSRPIQSPGRNSISP----GRNGIS 2337
            +S    + + IG S   PS   S   T +  +++ LS P  +     IS      R  IS
Sbjct: 3628 MSTPHGRITVIGTSLVTPSSDASAVKTETSTSERTLS-PSDTTASTPISTFSRVQRMSIS 3686

Query: 2338 PPNKLSQLPRTSSPSTASTKSSGSGKMSYTSPGRQMSQQNLTKQTGLSKNASSIP----R 2393
             P+ LS    TS   +++        M  T      +  N    T L  + S++     R
Sbjct: 3687 VPDILS----TSWTPSSTEAEDVPVSMVSTDHASTKTDPNTPLSTFLFDSLSTLDWDTGR 3742

Query: 2394 SESASKGLNQMNNGNGANKKVELSRMSSTKSS------GSESDRSERPVLVRQSTFIKEA 2447
            S S++        G    +++ L  M S  +S      G  +       + R S      
Sbjct: 3743 SLSSATATTSAPQGATTPQELTLETMISPATSQLPFSIGHITSAVTPAAMARSSGVTFSR 3802

Query: 2448 PSPTLRRKLEESASFESLSPSSRPASPTRSQAQTPVLSPSLPDMSLSTHSSVQAGGWRKL 2507
            P PT  +K E++++    + S+ P    RS A T      +P  + +  ++ Q  G   L
Sbjct: 3803 PDPT-SKKAEQTSTQLPTTTSAHPGQVPRSAATT---LDVIPHTAKTPDATFQRQGQTAL 3858

Query: 2508 PPNLSPTIEYNDGRPAKRHDIARSHSESPSRLPINRSGTWKREHSKHSSSLPRVSTWRRT 2567
                                 AR+ S+S           W  E  K + S P ++    +
Sbjct: 3859 TTE------------------ARATSDS-----------W-NEKEKSTPSAPWITEMMNS 3888

Query: 2568 GSSSSILSASSESSEKAKSEDEKHVNSISGTKQSKENQVSAKGTWRKIKENEFSPTNSTS 2627
             S  +I   +S SS   ++ +   +N  SGT  S         +W+       +P+ ST+
Sbjct: 3889 VSEDTIKEVTS-SSSVLRTLNTLDINLESGTTSSP--------SWKSSPYERIAPSESTT 3939

Query: 2628 QTVSSGATNGAESKTLIYQMAPAVSKTEDVWVRIEDCPINNPRSGRSPTGNTPPVIDSVS 2687
                         K  I+     V  T   WV           S    + +T P   + S
Sbjct: 3940 ------------DKEAIHPSTNTVETTG--WV----------TSSEHASHSTIPAHSASS 3975

Query: 2688 EKANPNIKDSKDNQAKQNVGNGSVPMRTVGLENRLNSFIQVDAPDQKGTEIKPGQNNPVP 2747
            +  +P +  S   QA  ++   + P  T       NSF+ ++  D     +         
Sbjct: 3976 KLTSPVVTTSTREQAIVSMSTTTWPEST-RARTEPNSFLTIELRD-VSPYMDTSSTTQTS 4033

Query: 2748 VSETNESSIVERTPFSSSSSSKHSSPS 2774
            +  +  S+ + + P +  +SSK  S S
Sbjct: 4034 IISSPGSTAITKGPRTEITSSKRISSS 4060



 Score = 37.0 bits (84), Expect = 0.28
 Identities = 107/483 (22%), Positives = 174/483 (36%), Gaps = 72/483 (14%)

Query: 2239  SSSSTSPVSKKGPPLKTPASKSPSEGQTATTSPRGAKPSVKSELSP---VARQTSQIGGS 2295
             SS      S     L  P + SPS   T   S   +  SV S L+P       TS   G+
Sbjct: 10011 SSLFVEKTSSSSSLLSLPVTTSPSVSSTLPQSIPSSSFSVTSLLTPGMVKTTDTSTEPGT 10070

Query: 2296  SKAPSRSG--------SRDSTPSRPAQQPLSRPIQSPGRNS----ISPGRNGISPPNKLS 2343
             S +P+ SG        S  +T +       S  + + G  S    +    +  S P+K +
Sbjct: 10071 SLSPNLSGTSVEILAASEVTTDTEKIHPSSSMAVTNVGTTSSGHELYSSVSIHSEPSKAT 10130

Query: 2344  QLPRTSSPSTASTKSSGSGKMSYTSPGRQMSQ-QNLT---KQTGLSKNASSI-PRSESAS 2398
                 T S S A T  S S   ++ + G +     +LT   ++T +S + SS+ P +  +S
Sbjct: 10131 YPVGTPS-SMAETSISTSMPANFETTGFEAEPFSHLTSGFRKTNMSLDTSSVTPTNTPSS 10189

Query: 2399  KGLNQMNNGNGANKKVELSRMSSTKSSG--SESDRSERPV----------LVRQSTFIKE 2446
              G   +   +    K + +  + T S      S  +E PV           + +ST I  
Sbjct: 10190 PGSTHLLQSS----KTDFTSSAKTSSPDWPPASQYTEIPVDIITPFNASPSITESTGITS 10245

Query: 2447  APSPTLRRKLEESASFES--LSPSSRPAS-----PTRSQAQTPVLSPSLPDM---SLSTH 2496
              P       + ES    S  L PS+   S     P+ S+A T   +  +P     S S  
Sbjct: 10246 FPESRFTMSVTESTHHLSTDLLPSAETISTGTVMPSLSEAMTSFATTGVPRAISGSGSPF 10305

Query: 2497  SSVQAGGWRKLPPNLSPTIEYNDGRPAKRHDIARSHSE---------SPSRLPINRSGTW 2547
             S  ++G        ++ ++  +   P        + S          S S  P     + 
Sbjct: 10306 SRTESGPGDATLSTIAESLPSSTPVPFSSSTFTTTDSSTIPALHEITSSSATPYRVDTSL 10365

Query: 2548  KREHSKHSSSLPRVSTWR------RTGSSSSILSASSESSEKAKSEDEKHVNSISGTKQS 2601
               E S     L  VST        RT SS  + +  +ES E         V S+S     
Sbjct: 10366 GTESSTTEGRLVMVSTLDTSSQPGRTSSSPILDTRMTESVELGTVTSAYQVPSLSTRLTR 10425

Query: 2602  KE----------NQVSAKGTWRKIKENEFSPTNSTSQTVSSGATNGAESKTLIYQMAPAV 2651
              +          N+ + +GT R +K  + S + ++ + + +G T   E+ T   +     
Sbjct: 10426 TDGIMEHITKIPNEAAHRGTIRPVKGPQTSTSPASPKGLHTGGTKRMETTTTALKTTTTA 10485

Query: 2652  SKT 2654
              KT
Sbjct: 10486 LKT 10488



 Score = 36.6 bits (83), Expect = 0.36
 Identities = 90/438 (20%), Positives = 153/438 (34%), Gaps = 63/438 (14%)

Query: 1205 SSKTEHMSSSSENTSTPSSNAKRQNQLHPSS-------AQSRSGQPQKAATCKVSSINQE 1257
            +S T ++SS+S    T   +      + PS+         S SG   +++    S   + 
Sbjct: 8319 TSSTSNLSSTSHERLTTLEDTVDTEDMQPSTHTAVTNVRTSISGHESQSSVLSDSETPKA 8378

Query: 1258 TIQ---TYCVEDTPICFS----------RCSSLSSLSSAEDEIGCNQTTQEADSANTLQI 1304
            T     TY + +T +  S          +    SSL+S   E   ++    A   +T+ +
Sbjct: 8379 TSPMGTTYTMGETSVSISTSDFFETSRIQIEPTSSLTSGLRETSSSERISSATEGSTV-L 8437

Query: 1305 AEIK----------EKIGTR----SAEDPVSEVPAVSQHPRTKSSRLQGSSLSSESARHK 1350
            +E+           E I +R    S  D  +  P +S    T   RL  S + +ESA   
Sbjct: 8438 SEVPSGATTEVSRTEVISSRGTSMSGPDQFTISPDISTEAIT---RLSTSPIMTESAE-S 8493

Query: 1351 AVEFSSGAKSPSKSGAQTPKSPPEHYVQETPLMFSRCTSVSSLDSFESRSIA-----SSV 1405
            A+   +G+   +  G  T  +    +   T    S   S S + +  SR+       S  
Sbjct: 8494 AITIETGSPGATSEGTLTLDTSTTTFWSGTHSTASPGFSHSEMTTLMSRTPGDVPWPSLP 8553

Query: 1406 QSEPCSGMVSGIISPSDLPDSPGQTMPPSRSKTPPP--------PPQTAQTKR--EVPKN 1455
              E  S + S + SP+    S   T+P S S +P P        P +T    R    P+ 
Sbjct: 8554 SVEEASSVSSSLSSPAMTSTSFFSTLPESISSSPHPVTALLTLGPVKTTDMLRTSSEPET 8613

Query: 1456 KAPTAEKRESGPKQAAVNAAVQRVQVLPDADTLLHFATESTPDGFSCSSSLSALSLDEPF 1515
             +P      S    A       R ++ P ++T +           S SS L+ L   +P 
Sbjct: 8614 SSPPNLSSTSAEILATSEVTKDREKIHPSSNTPVVNVGTVIYKHLSPSSVLADLVTTKP- 8672

Query: 1516 IQKDVELRIMPPVQENDNGNETESEQPKESNENQEKEAEKTIDSEKDLLDDSDDDDIEIL 1575
                      P    +  GN + S       E    +   ++ S    +  S +      
Sbjct: 8673 --------TSPMATTSTLGNTSVSTSTPAFPETMMTQPTSSLTSGLREISTSQETSSATE 8724

Query: 1576 EECIISAMPTKSSRKAKK 1593
                +S MPT ++ K  +
Sbjct: 8725 RSASLSGMPTGATTKVSR 8742



 Score = 35.8 bits (81), Expect = 0.62
 Identities = 69/318 (21%), Positives = 120/318 (37%), Gaps = 66/318 (20%)

Query: 1187  IPSSQKQSFSFSKSSSGQSSKTEHMSSSSENTSTPSSNAKRQNQLHPSS----AQSRSGQ 1242
             +P   K +     SS  ++S + ++SS+S      S       ++HPSS    A+ R+  
Sbjct: 9762  LPGLVKTTEVLDTSSEPKTSSSPNLSSTSVEIPATSEIMTDTEKIHPSSNTAVAKVRTSS 9821

Query: 1243  PQKAATCKVSSINQETIQ------TYCVEDTPI-----------------CFSRCSSLSS 1279
                 +   V + ++ TI       T  V+DT +                  FS       
Sbjct: 9822  SVHESHSSVLADSETTITIPSMGITSAVDDTTVFTSNPAFSETRRIPTEPTFSLTPGFRE 9881

Query: 1280  LSSAEDEIGCNQTTQEADSANTLQIAEIK--EKIGTRSAEDPVSEVPAVSQHPRTK-SSR 1336
              S++E+     +T+       T    E+   E + +     P S+   +S    T+  +R
Sbjct: 9882  TSTSEETTSITETSAVLYGVPTSATTEVSMTEIMSSNRIHIPDSDQSTMSPDIITEVITR 9941

Query: 1337  LQGSSLSSESARHKAV--EFSSGAKSPSKSGAQTPKSP---------------------- 1372
             L  SS+ SES +      + S GA + S     T  +P                      
Sbjct: 9942  LSSSSMMSESTQMTITTQKSSPGATAQSTLTLATTTAPLARTHSTVPPRFLHSEMTTLMS 10001

Query: 1373  --PEHYVQETPLMFSRCTSVSSLDSF---ESRSIASSV-QSEPCSG------MVSGIISP 1420
               PE+   ++ L   + +S SSL S     S S++S++ QS P S       +  G++  
Sbjct: 10002 RSPENPSWKSSLFVEKTSSSSSLLSLPVTTSPSVSSTLPQSIPSSSFSVTSLLTPGMVKT 10061

Query: 1421  SDLPDSPGQTMPPSRSKT 1438
             +D    PG ++ P+ S T
Sbjct: 10062 TDTSTEPGTSLSPNLSGT 10079



 Score = 34.3 bits (77), Expect = 1.8
 Identities = 30/111 (27%), Positives = 51/111 (45%), Gaps = 7/111 (6%)

Query: 1324 PAVSQHPRTKSSRLQGSSLSSESA-----RHKAVEFSSGAKSPSKSGAQTPKSP-PEHYV 1377
            PA +  P   ++ + GSS +SE++       KA+  S    +   SGA    S  PE  +
Sbjct: 2538 PATAFTPHLSAAVVTGSSATSEASLLTTSESKAIHSSPQTPTTPTSGANWETSATPESLL 2597

Query: 1378 QETPLMFSRCTS-VSSLDSFESRSIASSVQSEPCSGMVSGIISPSDLPDSP 1427
              T    +  TS +   D+    ++++     P +G +SG   P+ LPD+P
Sbjct: 2598 VVTETSDTTLTSKILVTDTILFSTVSTPPSKFPSTGTLSGASFPTLLPDTP 2648


>gi|7656879 ALL1 fused gene from 5q31 [Homo sapiens]
          Length = 1163

 Score = 55.5 bits (132), Expect = 8e-07
 Identities = 171/898 (19%), Positives = 324/898 (36%), Gaps = 162/898 (18%)

Query: 1180 SLKYATDIPSSQKQSFSFSKSSSGQSSKTEHMSSSSENTSTPSSNAKRQN-QLHPSSAQS 1238
            S K ++ + S      + + SSSG +S  +     S N S  SS  K Q+   H  S  S
Sbjct: 120  SQKRSSGLQSGHSSQRTSAGSSSGTNSSGQRHDRESYNNSGSSSRKKGQHGSEHSKSRSS 179

Query: 1239 RSGQPQKAATCKVSSINQETIQTYCVEDTPICFSRCSSLSSLSSAEDEIGCNQTTQEADS 1298
              G+PQ      VSS+N                    S  S S   D             
Sbjct: 180  SPGKPQA-----VSSLN--------------------SSHSRSHGNDH------------ 202

Query: 1299 ANTLQIAEIKEKIGTRSAEDPVSEVPAVSQHPRTKSSRLQGSSLSSESARHKAVEFSSGA 1358
                     KE   ++S  DP +   + S+ P +       S   S  ++  ++     A
Sbjct: 203  -------HSKEHQRSKSPRDPDANWDSPSRVPFSSGQHSTQSFPPSLMSKSNSMLQKPTA 255

Query: 1359 KSPSKSGAQT--PKSPPEHYVQETPLMFSRCTSVSSLD-SFESRSIASSVQSEPCSGMVS 1415
                  G ++  PK   EHY  +     S   S++ L  S ++      + S+P     S
Sbjct: 256  YVRPMDGQESMEPKLSSEHYSSQ-----SHGNSMTELKPSSKAHLTKLKIPSQPLDASAS 310

Query: 1416 GIISPSDLPDSPGQTMPPSRSKTPPPPPQTAQT--KREVPKNKAPTAEKRESGPKQAAVN 1473
            G +S  D        +    + + PPP     T  K E  K   PT E ++S        
Sbjct: 311  GDVSCVD-------EILKEMTHSWPPPLTAIHTPCKTEPSKFPFPTKESQQSN------F 357

Query: 1474 AAVQRVQVLPDADTLLHFATESTPDGFSCSSSLSALSLDEPFIQKDVELRIMPPVQENDN 1533
               ++ +  P   +  H +     D    SSS      ++   ++D + + MP  +    
Sbjct: 358  GTGEQKRYNPSKTSNGHQSKSMLKDDLKLSSS------EDSDGEQDCD-KTMP--RSTPG 408

Query: 1534 GNETESEQPKESNENQEKEAEKTIDSEKDLLDDSDDDDIEILEECIISAMPTKSSRKAKK 1593
             N   S    E  +N   ++     SE     DS+ +              + S  +A +
Sbjct: 409  SNSEPSHHNSEGADNSRDDSSSHSGSESSSGSDSESES-------------SSSDSEANE 455

Query: 1594 PAQTASKLPPPVARKPSQLPVYKLLPSQNRLQPQKHV--SFTPGDDMPRVYCVEGTPINF 1651
            P+Q+AS  P P      QL  +    + +++ P   V  +        +    +GT  ++
Sbjct: 456  PSQSASPEPEPPPTNKWQLDNWLNKVNPHKVSPASSVDSNIPSSQGYKKEGREQGTGNSY 515

Query: 1652 STATSLSDLTIESPPNELAAGEGVRGGAQSGEFEKRDTIPTEGRSTDEAQGGKTSSV-TI 1710
            +  +   + +  +P  +    + ++ G++SG           GR    AQ   T+   T+
Sbjct: 516  TDTSGPKETSSATPGRD---SKTIQKGSESGR----------GRQKSPAQSDSTTQRRTV 562

Query: 1711 PELDDNKAEEGDILAECINSAMPKGKSHKPFRVKKIMDQVQQASASSSAPNKNQLDGKKK 1770
             +    KAE+    AE     + K +S  P  +   M   +  +A+  +   N    KK+
Sbjct: 563  GKKQPKKAEKA--AAEEPRGGL-KIESETPVDLASSMPSSRHKAATKGSRKPNI---KKE 616

Query: 1771 KPTSPVKPIPQNTEYRTRVRKNADSKNNLNAERVFSDNKDSKKQNLKNNSKVF--NDKLP 1828
              +SP +P  +  +Y++  + +  S+  +  +   SD+ +S+     + +  +  +++ P
Sbjct: 617  SKSSP-RPTAEKKKYKSTSKSSQKSREIIETDTSSSDSDESESLPPSSQTPKYPESNRTP 675

Query: 1829 NNEDRVRGSFAFDSPHHYTPIEGTPYCFSRNDSLSSLDFDDD------DVDLS------- 1875
                 V    +F     ++P+E         + LS L   DD       +DL+       
Sbjct: 676  VKPSSVEEEDSFFRQRMFSPME-------EKELLSPLSEPDDRYPLIVKIDLNLLTRIPG 728

Query: 1876 -------REKAELRKAKENKESEAKVTSHTELTSNQQSANKTQ-----AIAKQP----IN 1919
                     K E +   E    EA+  +  ++++  +  +K +     + +K+P     N
Sbjct: 729  KPYKETEPPKGEKKNVPEKHTREAQKQASEKVSNKGKRKHKNEDDNRASESKKPKTEDKN 788

Query: 1920 RGQPKPILQKQSTFPQSSKD---IPDRGAATDEKLQNFAIENTPVCFSHNSSLSSLSDID 1976
                KP   ++S+   ++K+   +P        K       +     S +SSL S S+ +
Sbjct: 789  SAGHKPSSNRESSKQSAAKEKDLLPSPAGPVPSKDPKTEHGSRKRTISQSSSLKSSSNSN 848

Query: 1977 QENNNKENEPIKETEPPDSQGEPSKPQASGYAPKSFHVEDTPVCFSRNSSLSSLSIDS 2034
            +E +         ++   ++G+ S          S  V++     S N   S+ ++DS
Sbjct: 849  KETSGSSKNSSSTSKQKKTEGKTSS--------SSKEVKEKAPSSSSNCPPSAPTLDS 898



 Score = 47.4 bits (111), Expect = 2e-04
 Identities = 145/692 (20%), Positives = 245/692 (35%), Gaps = 115/692 (16%)

Query: 2241 SSTSPVSKKGPPLKTPASKSPSEGQTATTSPRGAKPSVKSELSPVARQTSQIGGSSKAPS 2300
            SS    ++  PP     S S  +  TA   P   + S++ +LS     +SQ  G+S    
Sbjct: 229  SSGQHSTQSFPPSLMSKSNSMLQKPTAYVRPMDGQESMEPKLSS-EHYSSQSHGNSMTEL 287

Query: 2301 RSGSRD-----STPSRPAQQPLSRPIQSPGR------NSISPGRNGISPPNKL--SQLPR 2347
            +  S+        PS+P     S  +           +S  P    I  P K   S+ P 
Sbjct: 288  KPSSKAHLTKLKIPSQPLDASASGDVSCVDEILKEMTHSWPPPLTAIHTPCKTEPSKFPF 347

Query: 2348 TSSPSTASTKSSGSGKM---SYTSPGRQMSQQNLTKQTGLSKNASS---------IPRSE 2395
             +  S  S   +G  K    S TS G Q S+  L     LS +  S         +PRS 
Sbjct: 348  PTKESQQSNFGTGEQKRYNPSKTSNGHQ-SKSMLKDDLKLSSSEDSDGEQDCDKTMPRST 406

Query: 2396 SASKGLNQMNNGNGANKKVE--LSRMSSTKSSGSESD--------RSERPVLVRQSTFIK 2445
              S      +N  GA+   +   S   S  SSGS+S+         +  P    QS   +
Sbjct: 407  PGSNSEPSHHNSEGADNSRDDSSSHSGSESSSGSDSESESSSSDSEANEP---SQSASPE 463

Query: 2446 EAPSPTLR------------RKLEESASFESLSPSSR-------------PASPTRSQAQ 2480
              P PT +             K+  ++S +S  PSS+               + T    +
Sbjct: 464  PEPPPTNKWQLDNWLNKVNPHKVSPASSVDSNIPSSQGYKKEGREQGTGNSYTDTSGPKE 523

Query: 2481 TPVLSPSLPDMSLSTHSSVQAGGWRKLPPNLSPTIEYNDGR--PAKRHDIA--------R 2530
            T   +P     ++   S    G  +    + S T     G+  P K    A        +
Sbjct: 524  TSSATPGRDSKTIQKGSESGRGRQKSPAQSDSTTQRRTVGKKQPKKAEKAAAEEPRGGLK 583

Query: 2531 SHSESP----SRLPINR-----SGTWKREHSKHSSSLPRVSTWRRTGSSSSILSASSESS 2581
              SE+P    S +P +R      G+ K    K S S PR +  ++   S+S      +SS
Sbjct: 584  IESETPVDLASSMPSSRHKAATKGSRKPNIKKESKSSPRPTAEKKKYKSTS------KSS 637

Query: 2582 EKAKSEDEKHVNSISGTKQSKENQVSAKGTWRKIKENEFSPTNSTSQTVSSG-----ATN 2636
            +K++   E   +S S + +S+    S++    K  E+  +P   +S             +
Sbjct: 638  QKSREIIETDTSS-SDSDESESLPPSSQTP--KYPESNRTPVKPSSVEEEDSFFRQRMFS 694

Query: 2637 GAESKTLIYQMA------PAVSKTE-DVWVRIEDCPINNPRSGRSPTGNTPP-------- 2681
              E K L+  ++      P + K + ++  RI   P       +    N P         
Sbjct: 695  PMEEKELLSPLSEPDDRYPLIVKIDLNLLTRIPGKPYKETEPPKGEKKNVPEKHTREAQK 754

Query: 2682 -VIDSVSEKANPNIKDSKDNQAKQNVGNGSVPMRTVGLENRLNSFIQVDAPDQKGTEIKP 2740
               + VS K     K+  DN+A ++    +    + G +   N      +   K  ++ P
Sbjct: 755  QASEKVSNKGKRKHKNEDDNRASESKKPKTEDKNSAGHKPSSNRESSKQSA-AKEKDLLP 813

Query: 2741 GQNNPVPVSETNESSIVERTPFSSSSSSKHSSPSGTVAARVTPFNYNPSPRKSSADSTSA 2800
                PVP  +        +   S SSS K SS S    +  +  + + S +K +   TS+
Sbjct: 814  SPAGPVPSKDPKTEHGSRKRTISQSSSLKSSSNSNKETSGSSKNSSSTSKQKKTEGKTSS 873

Query: 2801 RPSQIPTPVNNNTKKRDSKTDSTESSGTQSPK 2832
               ++     +++        + +SS  +  K
Sbjct: 874  SSKEVKEKAPSSSSNCPPSAPTLDSSKPRRTK 905



 Score = 40.8 bits (94), Expect = 0.019
 Identities = 99/503 (19%), Positives = 174/503 (34%), Gaps = 58/503 (11%)

Query: 766  AQHLSETFDNI--DNLSPKASHRSKQRHKQSLYGDYVFDTNRHDDNRSDNFNTG--NMTV 821
            + H SE  DN   D+ S   S  S     +S       + N    + S        N   
Sbjct: 414  SHHNSEGADNSRDDSSSHSGSESSSGSDSESESSSSDSEANEPSQSASPEPEPPPTNKWQ 473

Query: 822  LSPYLNTTVLPSSSSSRGSLDSSRSEKDRSLERERGIGLGNYHPATENPGTSSKRGLQIS 881
            L  +LN  V P   S   S+DS+        +  R  G GN +  T  P  +S      S
Sbjct: 474  LDNWLNK-VNPHKVSPASSVDSNIPSSQGYKKEGREQGTGNSYTDTSGPKETS------S 526

Query: 882  TTAAQIAKVMEEVSAIHTSQEDR--SSGSTTELHCVTDERNALRRSSAAHTHSNTYNFTK 939
             T  + +K +++ S     ++     S STT+   V  ++      +AA           
Sbjct: 527  ATPGRDSKTIQKGSESGRGRQKSPAQSDSTTQRRTVGKKQPKKAEKAAAEEPRGGLKIES 586

Query: 940  SENSNRTCSMPYAKLEYKRSSNDSLNSVSSSDGYGKRGQMKPSIESYSEDDESKFCSYGQ 999
                +   SMP                 SS      +G  KP+I+  S+          +
Sbjct: 587  ETPVDLASSMP-----------------SSRHKAATKGSRKPNIKKESKSSPRPTAEKKK 629

Query: 1000 YPADLAHKIHSANHMDDNDGELDTPINYSLKYSDEQLNSGRQSPSQNERWARPKHIIEDE 1059
            Y +       S   ++ +    D+  + SL  S +      + P  N    +P  + E++
Sbjct: 630  YKSTSKSSQKSREIIETDTSSSDSDESESLPPSSQT----PKYPESNRTPVKPSSVEEED 685

Query: 1060 IKQSEQRQSRNQSTTYPVYTESTDDKH---LKFQPHFGQQECVSPYRSRGANGSETNRVG 1116
                ++  S  +           DD++   +K   +   +    PY+       E   V 
Sbjct: 686  SFFRQRMFSPMEEKELLSPLSEPDDRYPLIVKIDLNLLTRIPGKPYKETEPPKGEKKNVP 745

Query: 1117 SNHG------INQNVSQSLCQEDDYEDDKPTNYSERYSEEEQHEEEERPTNY--SIKYN- 1167
              H        ++ VS    ++   EDD   + S++   E+++    +P++   S K + 
Sbjct: 746  EKHTREAQKQASEKVSNKGKRKHKNEDDNRASESKKPKTEDKNSAGHKPSSNRESSKQSA 805

Query: 1168 -EEKRHVDQPIDY-----------SLKYATDIPSSQKQSFSFSKSSSGQSSKTEHMSSSS 1215
             +EK  +  P              S K      SS K S + +K +SG S  +   S   
Sbjct: 806  AKEKDLLPSPAGPVPSKDPKTEHGSRKRTISQSSSLKSSSNSNKETSGSSKNSSSTSKQK 865

Query: 1216 ENTSTPSSNAKRQNQLHPSSAQS 1238
            +     SS++K   +  PSS+ +
Sbjct: 866  KTEGKTSSSSKEVKEKAPSSSSN 888



 Score = 37.0 bits (84), Expect = 0.28
 Identities = 46/193 (23%), Positives = 69/193 (35%), Gaps = 21/193 (10%)

Query: 2157 KPFTSNKGPRILKPG--EKSTLETKKIESESKGIKGGKKVYKSLITGKVRSNSEISGQMK 2214
            KP+   + P+  K    EK T E +K  SE    KG +K            +   + + K
Sbjct: 729  KPYKETEPPKGEKKNVPEKHTREAQKQASEKVSNKGKRK--------HKNEDDNRASESK 780

Query: 2215 QPLQANMPSISRGRTMIHIPGVRNSSSSTSPVSKKGPPLKTPASKSPSEGQTATTSPRGA 2274
            +P   +  S        H P   N  SS    +K+   L +PA   PS+        R  
Sbjct: 781  KPKTEDKNSAG------HKPS-SNRESSKQSAAKEKDLLPSPAGPVPSKDPKTEHGSRKR 833

Query: 2275 KPSVKSELSPVARQTSQIGGSSKAPSRSGSRDSTPSRPAQQPLSRPIQSPGRNSISPGRN 2334
              S  S L   +    +  GSSK  S +  +  T  + +        ++P  +S  P   
Sbjct: 834  TISQSSSLKSSSNSNKETSGSSKNSSSTSKQKKTEGKTSSSSKEVKEKAPSSSSNCPP-- 891

Query: 2335 GISPPNKLSQLPR 2347
              S P   S  PR
Sbjct: 892  --SAPTLDSSKPR 902


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.306    0.122    0.337 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 112,480,473
Number of Sequences: 37866
Number of extensions: 5634385
Number of successful extensions: 44545
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 151
Number of HSP's successfully gapped in prelim test: 1474
Number of HSP's that attempted gapping in prelim test: 30322
Number of HSP's gapped (non-prelim): 13502
length of query: 2843
length of database: 18,247,518
effective HSP length: 120
effective length of query: 2723
effective length of database: 13,703,598
effective search space: 37314897354
effective search space used: 37314897354
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.6 bits)
S2: 71 (32.0 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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