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Search of human proteins with 13376611
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|13376611 zinc finger protein 703 [Homo sapiens]
(590 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|13376611 zinc finger protein 703 [Homo sapiens] 1208 0.0
gi|24432032 zinc finger protein 503 [Homo sapiens] 598 e-171
gi|39812496 Sp8 transcription factor isoform 1 [Homo sapiens] 86 7e-17
gi|39812501 Sp8 transcription factor isoform 2 [Homo sapiens] 75 2e-13
gi|55750053 atrophin-1 [Homo sapiens] 64 5e-10
gi|55750041 atrophin-1 [Homo sapiens] 64 5e-10
gi|153792074 proline rich 12 [Homo sapiens] 62 2e-09
gi|153070260 myristoylated alanine-rich protein kinase C substra... 61 3e-09
gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens] 61 3e-09
gi|110832843 TBP-associated factor 4 [Homo sapiens] 59 1e-08
gi|4502961 alpha 1 type VII collagen precursor [Homo sapiens] 59 2e-08
gi|4502951 collagen type III alpha 1 preproprotein [Homo sapiens] 58 2e-08
gi|57864582 hornerin [Homo sapiens] 58 3e-08
gi|32964830 collagen, type VIII, alpha 2 [Homo sapiens] 57 5e-08
gi|89142737 alpha 3 type IV collagen isoform 5 precursor [Homo s... 57 6e-08
gi|89142735 alpha 3 type IV collagen isoform 4 precursor [Homo s... 57 6e-08
gi|89142733 alpha 3 type IV collagen isoform 2 precursor [Homo s... 57 6e-08
gi|89142730 alpha 3 type IV collagen isoform 1 precursor [Homo s... 57 6e-08
gi|110349772 alpha 1 type I collagen preproprotein [Homo sapiens] 56 1e-07
gi|148237270 hypermethylated in cancer 1 isoform 2 [Homo sapiens] 56 1e-07
gi|61676186 hypermethylated in cancer 1 isoform 1 [Homo sapiens] 56 1e-07
gi|163965366 nascent polypeptide-associated complex alpha subuni... 55 1e-07
gi|33946327 nucleoporin 214kDa [Homo sapiens] 55 2e-07
gi|28559039 mediator complex subunit 1 [Homo sapiens] 55 2e-07
gi|186928827 dermokine isoform 5 precursor [Homo sapiens] 54 3e-07
gi|47271406 bin3, bicoid-interacting 3 [Homo sapiens] 54 3e-07
gi|172072684 PR domain containing 1, with ZNF domain isoform 1 [... 54 4e-07
gi|33946274 PR domain containing 1, with ZNF domain isoform 2 [H... 54 4e-07
gi|186928825 dermokine isoform 3 precursor [Homo sapiens] 54 5e-07
gi|170650694 centaurin, gamma 1 isoform PIKE-L [Homo sapiens] 53 7e-07
>gi|13376611 zinc finger protein 703 [Homo sapiens]
Length = 590
Score = 1208 bits (3126), Expect = 0.0
Identities = 590/590 (100%), Positives = 590/590 (100%)
Query: 1 MSDSPAGSNPRTPESSGSGSGGGGKRPAVPAAVSLLPPADPLRQANRLPIRVLKMLSAHT 60
MSDSPAGSNPRTPESSGSGSGGGGKRPAVPAAVSLLPPADPLRQANRLPIRVLKMLSAHT
Sbjct: 1 MSDSPAGSNPRTPESSGSGSGGGGKRPAVPAAVSLLPPADPLRQANRLPIRVLKMLSAHT 60
Query: 61 GHLLHPEYLQPLSSTPVSPIELDAKKSPLALLAQTCSQIGKPDPPPSSKLNSVAAAANGL 120
GHLLHPEYLQPLSSTPVSPIELDAKKSPLALLAQTCSQIGKPDPPPSSKLNSVAAAANGL
Sbjct: 61 GHLLHPEYLQPLSSTPVSPIELDAKKSPLALLAQTCSQIGKPDPPPSSKLNSVAAAANGL 120
Query: 121 GAEKDPGRSAPGAASAAAALKQLGDSPAEDKSSFKPYSKGSGGGDSRKDSGSSSVSSTSS 180
GAEKDPGRSAPGAASAAAALKQLGDSPAEDKSSFKPYSKGSGGGDSRKDSGSSSVSSTSS
Sbjct: 121 GAEKDPGRSAPGAASAAAALKQLGDSPAEDKSSFKPYSKGSGGGDSRKDSGSSSVSSTSS 180
Query: 181 SSSSSPGDKAGFRVPSAACPPFPPHGAPVSASSSSSSPGGSRGGSPHHSDCKNGGGVGGG 240
SSSSSPGDKAGFRVPSAACPPFPPHGAPVSASSSSSSPGGSRGGSPHHSDCKNGGGVGGG
Sbjct: 181 SSSSSPGDKAGFRVPSAACPPFPPHGAPVSASSSSSSPGGSRGGSPHHSDCKNGGGVGGG 240
Query: 241 ELDKKDQEPKPSPEPAAVSRGGGGEPGAHGGAESGASGRKSEPPSALVGAGHVAPVSPYK 300
ELDKKDQEPKPSPEPAAVSRGGGGEPGAHGGAESGASGRKSEPPSALVGAGHVAPVSPYK
Sbjct: 241 ELDKKDQEPKPSPEPAAVSRGGGGEPGAHGGAESGASGRKSEPPSALVGAGHVAPVSPYK 300
Query: 301 PGHSVFPLPPSSIGYHGSIVGAYAGYPSQFVPGLDPSKSGLVGGQLSGGLGLPPGKPPSS 360
PGHSVFPLPPSSIGYHGSIVGAYAGYPSQFVPGLDPSKSGLVGGQLSGGLGLPPGKPPSS
Sbjct: 301 PGHSVFPLPPSSIGYHGSIVGAYAGYPSQFVPGLDPSKSGLVGGQLSGGLGLPPGKPPSS 360
Query: 361 SPLTGASPPSFLQGLCRDPYCLGGYHGASHLGGSSCSTCSAHDPAGPSLKAGGYPLVYPG 420
SPLTGASPPSFLQGLCRDPYCLGGYHGASHLGGSSCSTCSAHDPAGPSLKAGGYPLVYPG
Sbjct: 361 SPLTGASPPSFLQGLCRDPYCLGGYHGASHLGGSSCSTCSAHDPAGPSLKAGGYPLVYPG 420
Query: 421 HPLQPAALSSSAAQAALPGHPLYTYGFMLQNEPLPHSCNWVAASGPCDKRFATSEELLSH 480
HPLQPAALSSSAAQAALPGHPLYTYGFMLQNEPLPHSCNWVAASGPCDKRFATSEELLSH
Sbjct: 421 HPLQPAALSSSAAQAALPGHPLYTYGFMLQNEPLPHSCNWVAASGPCDKRFATSEELLSH 480
Query: 481 LRTHTALPGAEKLLAAYPGASGLGSAAAAAAAAASCHLHLPPPAAPGSPGSLSLRNPHTL 540
LRTHTALPGAEKLLAAYPGASGLGSAAAAAAAAASCHLHLPPPAAPGSPGSLSLRNPHTL
Sbjct: 481 LRTHTALPGAEKLLAAYPGASGLGSAAAAAAAAASCHLHLPPPAAPGSPGSLSLRNPHTL 540
Query: 541 GLSRYHPYGKSHLSTAGGLAVPSLPTAGPYYSPYALYGQRLASASALGYQ 590
GLSRYHPYGKSHLSTAGGLAVPSLPTAGPYYSPYALYGQRLASASALGYQ
Sbjct: 541 GLSRYHPYGKSHLSTAGGLAVPSLPTAGPYYSPYALYGQRLASASALGYQ 590
>gi|24432032 zinc finger protein 503 [Homo sapiens]
Length = 646
Score = 598 bits (1542), Expect = e-171
Identities = 360/666 (54%), Positives = 412/666 (61%), Gaps = 96/666 (14%)
Query: 1 MSDSPAGSNPRTPESSGSGSGGGGKRPAVPAAVSLL------------------------ 36
MS +P+ S R+ + SG G GGGG A PA S L
Sbjct: 1 MSTAPSLSALRSSKHSGGGGGGGGGGGADPAWTSALSGNSSGPGPGSSPAGSTKPFVHAV 60
Query: 37 PPADPLRQANRLPIRVLKMLSAHTGHLLHPEYLQPLSSTPVSPIELDAKKSPLALLAQTC 96
PP+DPLRQANRLPI+VLKML+A TGH+LHPEYLQPL STPVSPIELDAKKSPLALLAQTC
Sbjct: 61 PPSDPLRQANRLPIKVLKMLTARTGHILHPEYLQPLPSTPVSPIELDAKKSPLALLAQTC 120
Query: 97 SQIGKPDPPPSSKLNSVAAAANGLGAEKDPGRSAPGAASAAAALKQLGDSPAEDKSSFKP 156
SQIGKPDP PSSKL+SVA+ G G G A G + +L D EDKSSFKP
Sbjct: 121 SQIGKPDPSPSSKLSSVASNGGGAGG---AGGGAAGDKDTKSGPLKLSDIGVEDKSSFKP 177
Query: 157 YSK---------GSGGGDSRKDSGSSSVSSTSSSSSSSPGDKAGFRVPSAACPPFPPHGA 207
YSK G GGG G VSS +K+GFRVPSA C PF P
Sbjct: 178 YSKPGSDKKEPGGGGGGGGGGGGGGGGVSS----------EKSGFRVPSATCQPFTPRTG 227
Query: 208 PVSASSSSSSPGG---SRGGSPHHSDCKNGGGVGGGELDKKDQEPKPSPEPAA---VSRG 261
S+S+S+ SPGG S GG+P D K VGGG + P A +S G
Sbjct: 228 SPSSSASACSPGGMLSSAGGAPEGKDDKKDTDVGGGGKGTGGASAEGGPTGLAHGRISCG 287
Query: 262 GG----------GEPGAH------GGAESGASGRKSEPP--SALVGAGHVAPVSPYKPGH 303
GG G PG GG+ +SG P S+++G+G VAPVSPYKPG
Sbjct: 288 GGINVDVNQHPDGGPGGKALGSDCGGSSGSSSGSGPSAPTSSSVLGSGLVAPVSPYKPGQ 347
Query: 304 SVFPLPPSSIGYHGSIVGAYAGYPSQFVP---GLDPSKSG-LVGGQL----SGGLGLPPG 355
+VFPLPP+ + Y GS+ GAYAGYP QF+P LDP+K G LVG QL +G LG
Sbjct: 348 TVFPLPPAGMTYPGSLAGAYAGYPPQFLPHGVALDPTKPGSLVGAQLAAAAAGSLGC--S 405
Query: 356 KPPSSSPLTGASPPSFL-QGLCRDPYCLGGYHGASHLGGSSCSTCS-AHDPAGPSLK-AG 412
KP SSPL GASPPS + LCRDPYCL YH ASHL G++ ++ S AHDPA +
Sbjct: 406 KPAGSSPLAGASPPSVMTASLCRDPYCL-SYHCASHLAGAAAASASCAHDPAAAAAALKS 464
Query: 413 GYPLVYPGHPLQPAALSSSAAQAA------LPGHPLYTYGFMLQNEPLPHSCNWVAASGP 466
GYPLVYP HPL S +AA AA L GHPLY YGFML N+PLPH CNWV+A+GP
Sbjct: 465 GYPLVYPTHPLHGVHSSLTAAAAAGATPPSLAGHPLYPYGFMLPNDPLPHICNWVSANGP 524
Query: 467 CDKRFATSEELLSHLRTHTALPGAEKLLAAYPGASGLGSAAAAAAAAASCHLHLPPPAAP 526
CDKRFATSEELLSHLRTHTA PG +KLL+ YP +S L SAAAAA A CH+H+P AP
Sbjct: 525 CDKRFATSEELLSHLRTHTAFPGTDKLLSGYPSSSSLASAAAAAMA---CHMHIPTSGAP 581
Query: 527 GSPGSLSLRNP-HTLGL-SRYHPYGKSHLSTAGGLAVPSLPTAGPYYSPYALYGQRLASA 584
GSPG+L+LR+P H LGL SRYHPY KS L T G VP GPYYSPYALYGQRL +A
Sbjct: 582 GSPGTLALRSPHHALGLSSRYHPYSKSPLPTPGA-PVPVPAATGPYYSPYALYGQRLTTA 640
Query: 585 SALGYQ 590
SALGYQ
Sbjct: 641 SALGYQ 646
>gi|39812496 Sp8 transcription factor isoform 1 [Homo sapiens]
Length = 508
Score = 86.3 bits (212), Expect = 7e-17
Identities = 137/527 (25%), Positives = 186/527 (35%), Gaps = 122/527 (23%)
Query: 87 SPLALLAQTCSQIGKPDPPPSSKLNSVAAAANGLGAEKDPGRSAPGAAS-AAAALKQLGD 145
+PLA+LA TC++IG P P PSS +S ++ G K S+ + + ++L G
Sbjct: 15 TPLAMLAATCNKIGSPSPSPSSLSDSSSSFGKGFHPWKRSSSSSSASCNVVGSSLSSFGV 74
Query: 146 SPAEDKSSFKPYSKGSGGGDSRKDSGSSSVSSTSSSSSSSPGDKAGFRVPSAACPPFPPH 205
S A S + + + ++++ S S S SPG A S+A
Sbjct: 75 SGASRNGG----SSSAAAAAAAAAAAAAALVSDSFSCGGSPGSSAFSLTSSSAAA----- 125
Query: 206 GAPVSASSSSSSP--------------GGSRGGSPHHSDCKNGGGVGGGELDKKDQEPKP 251
A +A+++SSSP GGS GG GGG GG +D +P
Sbjct: 126 AAAAAAAAASSSPFANDYSVFQAPGVSGGSGGG--------GGGGGGGSSAHSQDGSHQP 177
Query: 252 ---SPEPAAVSRGGG-----------------GEPGAHGGAESGASGRKSEPPSALVGAG 291
S +V G PG E G++G S VGAG
Sbjct: 178 VFISKVHTSVDGLQGIYPRVGMAHPYESWFKPSHPGLGAAGEVGSAGASSWWD---VGAG 234
Query: 292 HVAPVSPYKPGHSVFPLPPSSIGYHGSIVGAYAGYPSQFVPGLDPS--KSGLVGGQLS-- 347
+ +P L P++ G S+ GY S + GL S SG LS
Sbjct: 235 WIDVQNPNSAAALPGSLHPAAGGLQTSLHSPLGGYNSDY-SGLSHSAFSSGASSHLLSPA 293
Query: 348 ------GGLGLPPGKPPSS--SPLTGASPPSFLQGLCRDPYCLGG--------YHGASHL 391
G + PG P S SPL GA G LGG Y G +
Sbjct: 294 GQHLMDGFKPVLPGSYPDSAPSPLAGAGGSMLSAGPSAP---LGGSPRSSARRYSGRATC 350
Query: 392 GGSSCSTCSAHDPAGPSLKAGGYPLVYPGHPLQPAALSSSAAQAALPGHPLYTYGFMLQN 451
+C PAG SL+ G + P + L H + G
Sbjct: 351 DCPNCQEAERLGPAGASLRRKGLHSCH-----IPGCGKVYGKTSHLKAHLRWHTG----- 400
Query: 452 EPLPHSCNWVAASGPCDKRFATSEELLSHLRTHT-----ALPGAEKL----------LAA 496
P CNW+ C KRF S+EL HLRTHT A P K +
Sbjct: 401 -ERPFVCNWLF----CGKRFTRSDELQRHLRTHTGEKRFACPVCNKRFMRSDHLSKHVKT 455
Query: 497 YPGASGLGSAAAAA-------------AAAASCHLHLPPPAAPGSPG 530
+ G G G +A + +AA S H P P PG
Sbjct: 456 HSGGGGGGGSAGSGSGGKKGSDTDSEHSAAGSPPCHSPELLQPPEPG 502
>gi|39812501 Sp8 transcription factor isoform 2 [Homo sapiens]
Length = 490
Score = 74.7 bits (182), Expect = 2e-13
Identities = 128/510 (25%), Positives = 179/510 (35%), Gaps = 96/510 (18%)
Query: 91 LLAQTCSQIGKPDPPPSSKLNSVAAAANGLGAEKDPGRSAPGAASAA-AALKQLGDSPAE 149
+LA TC++IG P P PSS +S ++ G K S+ + + ++L G S A
Sbjct: 1 MLAATCNKIGSPSPSPSSLSDSSSSFGKGFHPWKRSSSSSSASCNVVGSSLSSFGVSGAS 60
Query: 150 DKSSFKPYSKGSGGGDSRKDSGSSSVSSTSSSSSSSPGDKAGFRVPSAACPPFPPHGAPV 209
S + + + ++++ S S S SPG A S+A A
Sbjct: 61 RNGG----SSSAAAAAAAAAAAAAALVSDSFSCGGSPGSSAFSLTSSSAAA-----AAAA 111
Query: 210 SASSSSSSP--------------GGSRGGSPHHSDCKNGGGVGGGELDKKDQEPKP---S 252
+A+++SSSP GGS GG GGG GG +D +P S
Sbjct: 112 AAAAASSSPFANDYSVFQAPGVSGGSGGGG--------GGGGGGSSAHSQDGSHQPVFIS 163
Query: 253 PEPAAVSRGGG-----------------GEPGAHGGAESGASGRKSEPPSALVGAGHVAP 295
+V G PG E G++G S VGAG +
Sbjct: 164 KVHTSVDGLQGIYPRVGMAHPYESWFKPSHPGLGAAGEVGSAGASSWWD---VGAGWIDV 220
Query: 296 VSPYKPGHSVFPLPPSSIGYHGSIVGAYAGYPSQFVPGLDPS--KSGLVGGQLS------ 347
+P L P++ G S+ GY S + GL S SG LS
Sbjct: 221 QNPNSAAALPGSLHPAAGGLQTSLHSPLGGYNSDY-SGLSHSAFSSGASSHLLSPAGQHL 279
Query: 348 --GGLGLPPGKPPSS--SPLTGASPPSFLQGLCRDPYCLGG--------YHGASHLGGSS 395
G + PG P S SPL GA G LGG Y G + +
Sbjct: 280 MDGFKPVLPGSYPDSAPSPLAGAGGSMLSAGPSAP---LGGSPRSSARRYSGRATCDCPN 336
Query: 396 CSTCSAHDPAGPSLKAGGYPLVY-PGHPLQPAALSSSAAQAALPGHP------------- 441
C PAG SL+ G + PG +S +A L H
Sbjct: 337 CQEAERLGPAGASLRRKGLHSCHIPG--CGKVYGKTSHLKAHLRWHTGERPFVCNWLFCG 394
Query: 442 -LYTYGFMLQNEPLPHSCNWVAASGPCDKRFATSEELLSHLRTHTALPGAEKLLAAYPGA 500
+T LQ H+ A C+KRF S+ L H++TH+ G + G
Sbjct: 395 KRFTRSDELQRHLRTHTGEKRFACPVCNKRFMRSDHLSKHVKTHSGGGGGGGSAGSGSGG 454
Query: 501 SGLGSAAAAAAAAASCHLHLPPPAAPGSPG 530
+ +AA S H P P PG
Sbjct: 455 KKGSDTDSEHSAAGSPPCHSPELLQPPEPG 484
>gi|55750053 atrophin-1 [Homo sapiens]
Length = 1190
Score = 63.5 bits (153), Expect = 5e-10
Identities = 120/510 (23%), Positives = 166/510 (32%), Gaps = 121/510 (23%)
Query: 5 PAGSNPRTPESSGSGSGGGGKRPAVPAAVSLLPPADPLRQANRLPIRVLKMLSAHTGHLL 64
P + P + SSG+ K P P LP A P + T +L
Sbjct: 254 PPPTTPISVSSSGASGAPPTKPPTTPVGGGNLPSAPPPANFPHV-----------TPNLP 302
Query: 65 HPEYLQPLSSTPVSPIELDAKKSPLALLAQTCSQIGKPDPPPSSKLNSVAAAANGLGAEK 124
P L+PL++ SP L A+ P L + G PP + A +
Sbjct: 303 PPPALRPLNNASASPPGLGAQPLPGHLPSPHAMGQGMGGLPPGPEKGPTLAPS------- 355
Query: 125 DPGRSAPGAASAAAALKQLGDSPAEDKSSFKPYSKGSGGGDSRKDSGSSSVSS------- 177
P P ++SA A + S + S+ S S + S ++ S
Sbjct: 356 -PHSLPPASSSAPAPPMRFPYSSSSSSSAAASSSSSSSSSSASPFPASQALPSYPHSFPP 414
Query: 178 -TSSSSSSSPGDKAGFRVPSAAC-----PPFPPHGAPVSASSSSSSPGGSRGG------- 224
TS S S+ P +PS A PP PP+G ++ S++ P G
Sbjct: 415 PTSLSVSNQPPKYTQPSLPSQAVWSQGPPPPPPYGRLLANSNAHPGPFPPSTGAQSTAHP 474
Query: 225 --SPHHSDCKNGGGVGGGELDKKDQEPKPSPEPAAVSRGGGGEPGAHGGAESGASGRKSE 282
S HH + + ++ Q+ + + G PGA G S +
Sbjct: 475 PVSTHHHHHQQ------QQQQQQQQQQQQQQQQQHHGNSGPPPPGAFPHPLEGGSSHHAH 528
Query: 283 PPSALVGAGHVAPVSPYKPGHSVFPLPPSSIGY-----------------HGSIVGAY-- 323
P + G + PY PG + P P S + Y + G+Y
Sbjct: 529 PYAMSPSLG---SLRPYPPGPAHLPPPHSQVSYSQAGPNGPPVSSSSNSSSSTSQGSYPC 585
Query: 324 -----------AGYPSQFVPGLDPSK---SGLVGGQLSGGLGL----PPGKPP--SSSPL 363
A YP VP + S S ++ S G PPG PP +P
Sbjct: 586 SHPSPSQGPQGAPYPFPPVPTVTTSSATLSTVIATVASSPAGYKTASPPGPPPYGKRAPS 645
Query: 364 TGA------------SPPSFLQGLCRDPYCLGGYHGASHLGGSSCSTCSAHDPAGPSLKA 411
GA SPPSF G GY G S PAGP
Sbjct: 646 PGAYKTATPPGYKPGSPPSFRTG------TPPGYRGTS-------------PPAGPGTFK 686
Query: 412 GGYPLVYPGHPLQPAALSSSAAQAALPGHP 441
G P V PG PL PA S + P P
Sbjct: 687 PGSPTVGPG-PLPPAGPSGLPSLPPPPAAP 715
Score = 52.4 bits (124), Expect = 1e-06
Identities = 83/328 (25%), Positives = 117/328 (35%), Gaps = 55/328 (16%)
Query: 165 DSRKDSGSSSVSSTSSSSSSSPGDKAGFRVPSAACPPFPPHGAPVSASSSSSSP------ 218
D +D+ S+S S S S + D + A P PP P S S+P
Sbjct: 123 DIDQDNRSTSPSIYSPGSVENDSDSSSGLSQGPARPYHPPPLFPPSPQPPDSTPRQPEAS 182
Query: 219 ------------------------GGSRGGSPHHSDCKNGGGVGGGELDKKDQEPKPSPE 254
G P H GG GG L PK
Sbjct: 183 FEPHPSVTPTGYHAPMEPPTSRMFQAPPGAPPPHPQLYPGG--TGGVLSGPPMGPKGGGA 240
Query: 255 PAAVSRGGGGEPGAH-----GGAESGASGR-KSEPPSALVGAGHVAPVSPYKPGHSVFP- 307
++V GG+ + SGASG ++PP+ VG G++ P V P
Sbjct: 241 ASSVGGPNGGKQHPPPTTPISVSSSGASGAPPTKPPTTPVGGGNLPSAPPPANFPHVTPN 300
Query: 308 -LPPSSIGYHGSIVGAYAGYPSQFVPGLDPSKSGLVGGQLSGGLGLPPGKPPSSSPLTGA 366
PP ++ + + G +Q +PG PS + GQ GGL P K P+ +P +
Sbjct: 301 LPPPPALRPLNNASASPPGLGAQPLPGHLPSPHAM--GQGMGGLPPGPEKGPTLAPSPHS 358
Query: 367 SPPSFLQGLC---RDPYCLGGYHGASHLGGSSCSTCSAHDPAGPSLKAGGYPLVYPGHPL 423
PP+ R PY A+ SS S+ SA P S YP +P
Sbjct: 359 LPPASSSAPAPPMRFPYSSSSSSSAAASSSSSSSSSSA-SPFPASQALPSYPHSFP---- 413
Query: 424 QPAALSSS-----AAQAALPGHPLYTYG 446
P +LS S Q +LP +++ G
Sbjct: 414 PPTSLSVSNQPPKYTQPSLPSQAVWSQG 441
>gi|55750041 atrophin-1 [Homo sapiens]
Length = 1190
Score = 63.5 bits (153), Expect = 5e-10
Identities = 120/510 (23%), Positives = 166/510 (32%), Gaps = 121/510 (23%)
Query: 5 PAGSNPRTPESSGSGSGGGGKRPAVPAAVSLLPPADPLRQANRLPIRVLKMLSAHTGHLL 64
P + P + SSG+ K P P LP A P + T +L
Sbjct: 254 PPPTTPISVSSSGASGAPPTKPPTTPVGGGNLPSAPPPANFPHV-----------TPNLP 302
Query: 65 HPEYLQPLSSTPVSPIELDAKKSPLALLAQTCSQIGKPDPPPSSKLNSVAAAANGLGAEK 124
P L+PL++ SP L A+ P L + G PP + A +
Sbjct: 303 PPPALRPLNNASASPPGLGAQPLPGHLPSPHAMGQGMGGLPPGPEKGPTLAPS------- 355
Query: 125 DPGRSAPGAASAAAALKQLGDSPAEDKSSFKPYSKGSGGGDSRKDSGSSSVSS------- 177
P P ++SA A + S + S+ S S + S ++ S
Sbjct: 356 -PHSLPPASSSAPAPPMRFPYSSSSSSSAAASSSSSSSSSSASPFPASQALPSYPHSFPP 414
Query: 178 -TSSSSSSSPGDKAGFRVPSAAC-----PPFPPHGAPVSASSSSSSPGGSRGG------- 224
TS S S+ P +PS A PP PP+G ++ S++ P G
Sbjct: 415 PTSLSVSNQPPKYTQPSLPSQAVWSQGPPPPPPYGRLLANSNAHPGPFPPSTGAQSTAHP 474
Query: 225 --SPHHSDCKNGGGVGGGELDKKDQEPKPSPEPAAVSRGGGGEPGAHGGAESGASGRKSE 282
S HH + + ++ Q+ + + G PGA G S +
Sbjct: 475 PVSTHHHHHQQ------QQQQQQQQQQQQQQQQQHHGNSGPPPPGAFPHPLEGGSSHHAH 528
Query: 283 PPSALVGAGHVAPVSPYKPGHSVFPLPPSSIGY-----------------HGSIVGAY-- 323
P + G + PY PG + P P S + Y + G+Y
Sbjct: 529 PYAMSPSLG---SLRPYPPGPAHLPPPHSQVSYSQAGPNGPPVSSSSNSSSSTSQGSYPC 585
Query: 324 -----------AGYPSQFVPGLDPSK---SGLVGGQLSGGLGL----PPGKPP--SSSPL 363
A YP VP + S S ++ S G PPG PP +P
Sbjct: 586 SHPSPSQGPQGAPYPFPPVPTVTTSSATLSTVIATVASSPAGYKTASPPGPPPYGKRAPS 645
Query: 364 TGA------------SPPSFLQGLCRDPYCLGGYHGASHLGGSSCSTCSAHDPAGPSLKA 411
GA SPPSF G GY G S PAGP
Sbjct: 646 PGAYKTATPPGYKPGSPPSFRTG------TPPGYRGTS-------------PPAGPGTFK 686
Query: 412 GGYPLVYPGHPLQPAALSSSAAQAALPGHP 441
G P V PG PL PA S + P P
Sbjct: 687 PGSPTVGPG-PLPPAGPSGLPSLPPPPAAP 715
Score = 52.4 bits (124), Expect = 1e-06
Identities = 83/328 (25%), Positives = 117/328 (35%), Gaps = 55/328 (16%)
Query: 165 DSRKDSGSSSVSSTSSSSSSSPGDKAGFRVPSAACPPFPPHGAPVSASSSSSSP------ 218
D +D+ S+S S S S + D + A P PP P S S+P
Sbjct: 123 DIDQDNRSTSPSIYSPGSVENDSDSSSGLSQGPARPYHPPPLFPPSPQPPDSTPRQPEAS 182
Query: 219 ------------------------GGSRGGSPHHSDCKNGGGVGGGELDKKDQEPKPSPE 254
G P H GG GG L PK
Sbjct: 183 FEPHPSVTPTGYHAPMEPPTSRMFQAPPGAPPPHPQLYPGG--TGGVLSGPPMGPKGGGA 240
Query: 255 PAAVSRGGGGEPGAH-----GGAESGASGR-KSEPPSALVGAGHVAPVSPYKPGHSVFP- 307
++V GG+ + SGASG ++PP+ VG G++ P V P
Sbjct: 241 ASSVGGPNGGKQHPPPTTPISVSSSGASGAPPTKPPTTPVGGGNLPSAPPPANFPHVTPN 300
Query: 308 -LPPSSIGYHGSIVGAYAGYPSQFVPGLDPSKSGLVGGQLSGGLGLPPGKPPSSSPLTGA 366
PP ++ + + G +Q +PG PS + GQ GGL P K P+ +P +
Sbjct: 301 LPPPPALRPLNNASASPPGLGAQPLPGHLPSPHAM--GQGMGGLPPGPEKGPTLAPSPHS 358
Query: 367 SPPSFLQGLC---RDPYCLGGYHGASHLGGSSCSTCSAHDPAGPSLKAGGYPLVYPGHPL 423
PP+ R PY A+ SS S+ SA P S YP +P
Sbjct: 359 LPPASSSAPAPPMRFPYSSSSSSSAAASSSSSSSSSSA-SPFPASQALPSYPHSFP---- 413
Query: 424 QPAALSSS-----AAQAALPGHPLYTYG 446
P +LS S Q +LP +++ G
Sbjct: 414 PPTSLSVSNQPPKYTQPSLPSQAVWSQG 441
>gi|153792074 proline rich 12 [Homo sapiens]
Length = 2036
Score = 61.6 bits (148), Expect = 2e-09
Identities = 145/588 (24%), Positives = 192/588 (32%), Gaps = 130/588 (22%)
Query: 27 PAVPAAVSLLPPADPLR----QANRLPIRV-LKMLSAHTGHLLHPEYLQPLSSTPVSPIE 81
P P A LL P D L QA +P + + L+ G +L P L P + P P
Sbjct: 174 PFSPPANGLLSPHDVLHLKPSQAPTVPSSLGFERLAG--GGVLGPAGLGPAQTPPYRP-- 229
Query: 82 LDAKKSPLALLAQTCSQIGKPDPPPSSK-------LNSVAAAANGLGAEKDP-----GRS 129
G PDPPP + L + ++AA + P +
Sbjct: 230 ------------------GPPDPPPPPRHLPTQFNLLASSSAAAAAAEQSSPQLYNFSGA 271
Query: 130 APGAASAAAALKQLGDSPAEDKSSFKPYSKGSGGGDSRKDSGSSSVSSTSSSSSSSPGDK 189
APG AL P +D + K Y + + + ++ S S P
Sbjct: 272 APGPPPPERAL------PRQD-TVIKHYQRPASAQPPPPPPPAHALQHYLSCGGSYPS-- 322
Query: 190 AGFRVPSAACP-----PFPPHGAPVSASSSSSSPGGSRGGSPHHSDCKNGGGVGGGELDK 244
G R A P P P G P A S ++ G S G + GGG GGG
Sbjct: 323 MGHRANLACSPLGGGEPSPGAGEPSKAGPSGATAGAS--GRATGPEAAGGGGAGGG---- 376
Query: 245 KDQEPKPSPEPAAVSRGGGGEPGAHGGAESGASGRKSEPPSALVGAGHVAPVSPYKPGHS 304
+P + G GG A GGA R + P G P + Y G
Sbjct: 377 -GGGYRPIIQSPGYKTGKGGYGAAAGGATRPPPPRSTATPKCQSLGG---PAAAYATG-- 430
Query: 305 VFPLPPSSIGYHGSIVGAYAGYPSQFVPGLDPSKSGLVGGQ---------LSGGLGLPPG 355
+ G G+ AY+ Q + G G GGQ SGG PP
Sbjct: 431 ------KASGAGGAGGQAYSPGQPQGLLGPQAYGQGFGGGQAQDLSKAPSYSGGPPQPPS 484
Query: 356 KPPSSSPLTGAS-PPSFLQ----GLCRDPYCLGGYHGAS-HLGGSSCSTCSAHDPA---- 405
PP T S P LQ G+ +PY H S S + H PA
Sbjct: 485 GPPPPGLATCQSYSPDQLQGQLYGVQGEPYPGPAAHSQGLPTASPSLSYSTGHSPALSGH 544
Query: 406 ----GPSLKAGGYPLVYPGH---PLQPAALSSSAAQAALPGHPLYTYGFMLQNEPL---P 455
GPS GG P H PLQ + PG P +L + P P
Sbjct: 545 GGGWGPSSLGGGGE-ASPSHIIRPLQSPPATGRPPGVGSPGAPGKYLSSVLASAPFLAPP 603
Query: 456 HSCNWVAAS-----------------GPCDKRFATSEELLSHLRTHTALPGAEKLLAAYP 498
+ ++ A + GP +R E L+ HL + P
Sbjct: 604 GAGSYAAGAGGYKGKGDGSELLAGPGGPPAERTEDEEFLIQHLLQAPSPPRTS------- 656
Query: 499 GASGLGSAAAAAAAAASCHLHLPPPAAPGSPGSLSLRNPHTLGLSRYH 546
GA GL AA A+ PG+P L+ +P RYH
Sbjct: 657 GADGLVGEDGAADASKGLGGSGGAGGPPGTPYELAKEDP-----QRYH 699
>gi|153070260 myristoylated alanine-rich protein kinase C substrate
[Homo sapiens]
Length = 332
Score = 61.2 bits (147), Expect = 3e-09
Identities = 89/352 (25%), Positives = 128/352 (36%), Gaps = 78/352 (22%)
Query: 105 PPSSKLNSVAAAANGL--GAEKDPGRSAPGAASAAA--ALKQLGDSPAEDKSSFKPYSKG 160
P + + S + ANG G K G ++P AA + A L+ G +PA DK +P + G
Sbjct: 19 PGEAAVASSPSKANGQENGHVKVNGDASPAAAESGAKEELQANGSAPAADKE--EPAAAG 76
Query: 161 SGGGDSRKDSGSSSVSSTSSSSSSSPGDKAGFRVPSAACP--PFPPHGAPVSASSSSSSP 218
SG ++ + + +SP +K AA P P G SA+SS+SSP
Sbjct: 77 SGAASPSAAEKGEPAAAAAPEAGASPVEKEAPAEGEAAEPGSPTAAEGEAASAASSTSSP 136
Query: 219 GGSRGGSPHHSD-----------CKNGGGVGGGELDKKDQEPKPSPEPAAVSRGGGGE-- 265
G +P S+ K + G K +E G GGE
Sbjct: 137 KAEDGATPSPSNETPKKKKKRFSFKKSFKLSGFSFKKNKKE-----------AGEGGEAE 185
Query: 266 -PGAHGGAESGASGRKSEPPSALVGAGHVAPVSPYKPGHSVFPLPPSSIGYHGSIVGAYA 324
P A GG + A G + A +G A PG ++ G GA
Sbjct: 186 APAAEGGKDEAAGGAAAAAAEAGAASGEQAAA----PGEE------AAAGEE----GAAG 231
Query: 325 GYPSQFVPGLDPSKSGLVGGQLSGGLGLPPGKPPSSSPLTGASPPSFLQGLCRDPYCLGG 384
G P + P + P KPP+S A PS ++
Sbjct: 232 GDPQEAKP---------------QEAAVAPEKPPASDETKAAEEPSKVE----------- 265
Query: 385 YHGASHLGGSSCSTCSAHDPAGPSLKAGGYPLVYPGHPLQPAALSSSAAQAA 436
+ G+S + C A AGP G P +PAA ++S+A AA
Sbjct: 266 -EKKAEEAGASAAACEAPSAAGP----GAPPEQEAAPAEEPAAAAASSACAA 312
Score = 37.0 bits (84), Expect = 0.051
Identities = 53/239 (22%), Positives = 81/239 (33%), Gaps = 24/239 (10%)
Query: 67 EYLQPLSSTPVSPIELDAKKSPLALLAQTCSQIGKPDPP--PSSKLNSVAAAANGLGAEK 124
E LQ S P + E A A + + ++ G+P P + + V A G
Sbjct: 56 EELQANGSAPAADKEEPAAAGSGAA-SPSAAEKGEPAAAAAPEAGASPVEKEAPAEGEAA 114
Query: 125 DPGRSAPGAASAAAALKQLGDSPAED----------------KSSFKPYSKGSGGGDSRK 168
+PG AA+A AED + SFK K SG +
Sbjct: 115 EPGSPTAAEGEAASAASSTSSPKAEDGATPSPSNETPKKKKKRFSFKKSFKLSGFSFKKN 174
Query: 169 DSGSSSVSSTSSSSSSSPGDKAGFRVPSAACPPFPPHGAPVSASSSSSSPG--GSRGGSP 226
+ + ++ D+A +AA G +A ++ G G+ GG P
Sbjct: 175 KKEAGEGGEAEAPAAEGGKDEAAGGAAAAAAEAGAASGEQAAAPGEEAAAGEEGAAGGDP 234
Query: 227 HHSDCKNGGGVGGGELDKKDQEPKPSPEPAAVSRGGGGEPGAHGGA-ESGASGRKSEPP 284
+ K E E K + EP+ V E GA A E+ ++ PP
Sbjct: 235 Q--EAKPQEAAVAPEKPPASDETKAAEEPSKVEEKKAEEAGASAAACEAPSAAGPGAPP 291
Score = 35.0 bits (79), Expect = 0.19
Identities = 73/323 (22%), Positives = 98/323 (30%), Gaps = 29/323 (8%)
Query: 215 SSSPGGSRGGSPHHSDCKNGGGVGGGELDKKDQEPKPSPEPAAVSRGGGGEPGAHG-GAE 273
+SSP + G H E K++ PAA EP A G GA
Sbjct: 25 ASSPSKANGQENGHVKVNGDASPAAAESGAKEELQANGSAPAADKE----EPAAAGSGAA 80
Query: 274 SGASGRKSEPPSALVGAGHVAPVSPYKPGHSVFPLPPSSIGYHGSIVGAYAGYPS-QFVP 332
S ++ K EP +A +PV P P S G A + S +
Sbjct: 81 SPSAAEKGEPAAAAAPEAGASPVEKEAPAEGEAAEPGSPTAAEGEAASAASSTSSPKAED 140
Query: 333 GLDPSKSGLVGGQLSGGLGLPPGKPPSSSPLTGASPPSFLQGLCRDPYCLGGYHGASHLG 392
G PS S + S + G P GG A+ G
Sbjct: 141 GATPSPSNETPKKKKKRFSFKKSFKLSGFSFKKNKKEAGEGGEAEAPAAEGGKDEAA--G 198
Query: 393 GSSCSTCSAHDPAGPSLKAGGYPLVYPGHPLQPAALSSSAAQAALPGHPLYTYGFMLQNE 452
G++ + A +G A G + AA A P + +
Sbjct: 199 GAAAAAAEAGAASGEQAAAPG----------EEAAAGEEGAAGGDPQEAKPQEAAVAPEK 248
Query: 453 PLPHSCNWVAASGPCDKRFATSEELLSHLRT----HTALPGAEKLLAAYPGASGLGSAAA 508
P P S AA P +EE + A PGA A P +AA+
Sbjct: 249 P-PASDETKAAEEPSKVEEKKAEEAGASAAACEAPSAAGPGAPPEQEAAPAEEPAAAAAS 307
Query: 509 AAAAAAS------CHLHLPPPAA 525
+A AA S C PP A
Sbjct: 308 SACAAPSQEAQPECSPEAPPAEA 330
>gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens]
Length = 2752
Score = 61.2 bits (147), Expect = 3e-09
Identities = 63/250 (25%), Positives = 95/250 (38%), Gaps = 21/250 (8%)
Query: 55 MLSAHTGHLLHPEYLQPLSSTPVSPIELDAKKSPLALLAQTCSQIGKPDPPPSSKLNSVA 114
MLS + H + +P +ST A P + S SS +S +
Sbjct: 2493 MLSVPAPGVPHSDVGEPPASTGAQQPSALAALQPAKERRSSSSSSSSSSSSSSSSSSSSS 2552
Query: 115 AAANGLGAEKDPGRSAPGAASAAAALKQL-------------GDSPAEDKSSFKPYSKGS 161
++++G + G S P ALK++ G P + K S S
Sbjct: 2553 SSSSGSSSSDSEGSSLP--VQPEVALKRVPSPTPAPKEAVREGRPPEPTPAKRKRRSSSS 2610
Query: 162 GGGDSRKDSGSSSVSSTSSSSSSSPGDKAGFRVPSAACPPFP---PHGAPVSASSSSSSP 218
S S SSS SS+SSSSSSS + S++ P P P AS P
Sbjct: 2611 SSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSPSPAKPGPQALPKPASPKKPPP 2670
Query: 219 GGSRGGSPHH--SDCKNGGGVGGGELDKKDQEPKPSP-EPAAVSRGGGGEPGAHGGAESG 275
G R SP ++ + ++++ P+PSP + + S G G G + S
Sbjct: 2671 GERRSRSPRKPIDSLRDSRSLSYSPVERRRPSPQPSPRDQQSSSSERGSRRGQRGDSRSP 2730
Query: 276 ASGRKSEPPS 285
+ R+ E PS
Sbjct: 2731 SHKRRRETPS 2740
Score = 58.9 bits (141), Expect = 1e-08
Identities = 76/321 (23%), Positives = 116/321 (36%), Gaps = 37/321 (11%)
Query: 1 MSDSPAGSN---PRTPESSGSGSGGGGKRPAVPAAVSLLPPADPLRQANRLPIRVLKMLS 57
M+ + +G+N PR P S+ G P + A S PP+ P + +R+ S
Sbjct: 2371 MAPALSGANLTSPRVPLSAYERVSGRTSPPLLDRARSRTPPSAPSQ--SRMTSERAPSPS 2428
Query: 58 AHTGHLLHPEYLQPLSSTPVSPIELDAKKSPLALLAQTCSQIGKPDPPPSSKLNSVAAAA 117
+ G L P P SP+ L+AQT G + + ++A
Sbjct: 2429 SRMGQAPSQSLLPPAQDQPRSPVPSAFSDQSRCLIAQTTPVAGSQSLSSGAVATTTSSAG 2488
Query: 118 NGLGAEKDPGRSAPGAASAAAALKQLGDSPAEDKSSFKPYSKGSGGGDSRKDSGSSSVSS 177
+ G P APG + +G+ PA + R+ S SSS SS
Sbjct: 2489 DHNGMLSVP---APGVPHS-----DVGEPPASTGAQQPSALAALQPAKERRSSSSSSSSS 2540
Query: 178 TSSSSSSSPGDKAGFRVPSAACPPFPPHGAPVSASSSSSSPGGSRGGSPHHSDCKNGGGV 237
+SSSSSSS + S SSSS S G S P + +
Sbjct: 2541 SSSSSSSSSSSSSSS-----------------SGSSSSDSEGSSLPVQPEVALKRVPSPT 2583
Query: 238 GGG-ELDKKDQEPKPSP------EPAAVSRGGGGEPGAHGGAESGASGRKSEPPSALVGA 290
E ++ + P+P+P ++ S + + S +S S S+ +
Sbjct: 2584 PAPKEAVREGRPPEPTPAKRKRRSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2643
Query: 291 GHVAPVSPYKPGHSVFPLPPS 311
+ SP KPG P P S
Sbjct: 2644 SSSSSPSPAKPGPQALPKPAS 2664
Score = 41.6 bits (96), Expect = 0.002
Identities = 66/265 (24%), Positives = 91/265 (34%), Gaps = 27/265 (10%)
Query: 10 PRTPESSGSGSGGGGKRPA--VPAAVSLLPPADPLRQANRLPIRVLKMLSAHTGHLLHPE 67
PRTP G R P+ SL + ++ R P R + P+
Sbjct: 1432 PRTPSRRSRSGSSPGLRDGSGTPSRHSLSGSSPGMKDIPRTPSRGRSECDSSPEPKALPQ 1491
Query: 68 YLQPLSSTPVSPIELDAKKSPLALLAQTCSQIGKPDPPPSSKLNSVAAAANGLGAEKDPG 127
+P S +P SP EL+ K C + S ++ A LG G
Sbjct: 1492 TPRPRSRSPSSP-ELNNK----------CLTPQRERSGSESSVDQKTVARTPLGQRSRSG 1540
Query: 128 RSAPGAASAAAALKQLGDSPAEDKSSFK---PYSKGSGGGDSRKDSGSSSVSSTSSSSSS 184
S +A+ ++ +S + S K P + S G S + S +S S S S
Sbjct: 1541 SSQELDVKPSASPQERSESDSSPDSKAKTRTPLRQRSRSGSSPEVDSKSRLSPRRSRSGS 1600
Query: 185 SPGDKAGFRVPSAA-----CPPFP----PHGAPVSASSSSSSPGGSRGGSPHHSDCKNGG 235
SP K R A P P P P + S SSS G RG SP S
Sbjct: 1601 SPEVKDKPRAAPRAQSGSDSSPEPKAPAPRALPRRSRSGSSSKG--RGPSPEGSSSTESS 1658
Query: 236 GVGGGELDKKDQEPKPSPEPAAVSR 260
+ + + SPEP SR
Sbjct: 1659 PEHPPKSRTARRGSRSSPEPKTKSR 1683
Score = 36.2 bits (82), Expect = 0.087
Identities = 97/453 (21%), Positives = 145/453 (32%), Gaps = 76/453 (16%)
Query: 8 SNPRTPESSGSGSGGGGKRPAVPAAVSLLPPADPLRQANRLPIRVLKMLSAHTGHLLHPE 67
++ RTP ++ + + + P+AV+L ADP
Sbjct: 2257 ADSRTPAAAAAMNLASPRTAVAPSAVNL---ADP-------------------------- 2287
Query: 68 YLQPLSSTPVSP-IELDAKKSPLALLAQTCSQIGKP----DPPPSSKLNSVAAAANGLG- 121
TP +P + L ++P AL A + + G P + P SS+ A+AN +G
Sbjct: 2288 ------RTPTAPAVNLAGARTPAALAALSLTGSGTPPTAANYPSSSRTPQAPASANLVGP 2341
Query: 122 ------AEKDPGRSAPGAASAAAALKQLGDSPA-------EDKSSFKPYSKGSG------ 162
A + S AA A A+L +PA + Y + SG
Sbjct: 2342 RSAHATAPVNIAGSRTAAALAPASLTSARMAPALSGANLTSPRVPLSAYERVSGRTSPPL 2401
Query: 163 --GGDSRKDSGSSSVSSTSSSSSSSPGDKAGFRVPSAACPPF--PPHGAPVSASSSSSSP 218
SR + S S +S + SP + G + PP P SA S S
Sbjct: 2402 LDRARSRTPPSAPSQSRMTSERAPSPSSRMGQAPSQSLLPPAQDQPRSPVPSAFSDQSRC 2461
Query: 219 GGSRGGSPHHSDCKNGGGVGGGELDKKDQEPKPSPEPAAVSRGGGGEPGAHGGAESGASG 278
++ S + G V D S V GEP A GA+ ++
Sbjct: 2462 LIAQTTPVAGSQSLSSGAVATTTSSAGDHNGMLSVPAPGVPHSDVGEPPASTGAQQPSAL 2521
Query: 279 RKSEPPSALVGAGHVAPVSPYKPGHSVFPLPPSSIG-----YHGSIVGAYAGYPSQFVPG 333
+P + + S S SS G GS + + VP
Sbjct: 2522 AALQPAKERRSSSSSSSSSSSSSSSSSSSSSSSSSGSSSSDSEGSSLPVQPEVALKRVPS 2581
Query: 334 LDPSKSGLVGGQLSGGLGLPPGKPPSSSPLTGASPPSFLQGLCRDPYCLGGYHGASHLGG 393
P+ V G PP P+ +S S +S
Sbjct: 2582 PTPAPKEAVRE------GRPPEPTPAKRKRRSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2635
Query: 394 SSCSTCSAHDPAGPS-LKAGGYPLVYPGHPLQP 425
SS S+ S+ + PS K G L P P +P
Sbjct: 2636 SSSSSSSSSSSSSPSPAKPGPQALPKPASPKKP 2668
Score = 33.5 bits (75), Expect = 0.56
Identities = 108/534 (20%), Positives = 188/534 (35%), Gaps = 92/534 (17%)
Query: 13 PESSGSGSGGGGKRPAVPAAVSL--LPPADPLRQANRLPIR---VLKMLSAHTGHLLHPE 67
P S S +G + VPA V L L A A+R+P + + SA T +
Sbjct: 2195 PPPSMSAAGLAARMSQVPAPVPLMSLRTAPAANLASRIPAASAAAMNLASARTPAIPTAV 2254
Query: 68 YLQPLSSTPVSPIELDAKKSPLALLAQTCSQIGKPDPPPSSKLNSVAAAANGLGAEKDPG 127
L S TP + ++ SP +A + + P P A A N GA
Sbjct: 2255 NLAD-SRTPAAAAAMNLA-SPRTAVAPSAVNLADPRTP-------TAPAVNLAGAR---- 2301
Query: 128 RSAPGAASAAAALKQLGDSPAEDKSSFKPYSKGSGGGDSRKDSGSSSVSSTSSSSSSSPG 187
+A AAL G +++ S+ + + S+++ S+ +++P
Sbjct: 2302 -----TPAALAALSLTGSGTPPTAANYPSSSR------TPQAPASANLVGPRSAHATAPV 2350
Query: 188 DKAGFRVPSAACPPFPPHG--APVSASSSSSSPGGSRGGSPHHSDCKNGGGVGGGELDK- 244
+ AG R +A P AP + ++ +SP P + + G LD+
Sbjct: 2351 NIAGSRTAAALAPASLTSARMAPALSGANLTSPR-----VPLSAYERVSGRTSPPLLDRA 2405
Query: 245 KDQEPKPSPEPAAVSRGGGGEPGAHGGAESGAS-------GRKSEPPSALVGAGH--VAP 295
+ + P +P + ++ P + G S +S PSA +A
Sbjct: 2406 RSRTPPSAPSQSRMTSERAPSPSSRMGQAPSQSLLPPAQDQPRSPVPSAFSDQSRCLIAQ 2465
Query: 296 VSPYKPGHSVFPLPPSSIGYHGSIVGAYAGYPSQFVPGLDPSKSGLVGGQLSGGLGLPPG 355
+P S L ++ S G + G S PG+ S G
Sbjct: 2466 TTPVAGSQS---LSSGAVATTTSSAGDHNGMLSVPAPGVPHSDVG--------------- 2507
Query: 356 KPPSSSPLTGASPPSFLQGL--CRDPYCLGGYHGASHLGGSSCSTCSAHDPAGPSLKAGG 413
+PP+S TGA PS L L ++ +S SS S+ S+ +G S
Sbjct: 2508 EPPAS---TGAQQPSALAALQPAKERRSSSSSSSSSSSSSSSSSSSSSSSSSGSS----- 2559
Query: 414 YPLVYPGHPLQPAALSSSAAQAALPGHPLYTYGFMLQNEPLPHSCNWVAASGPCDKRFAT 473
SS + ++LP P + P P G +
Sbjct: 2560 ---------------SSDSEGSSLPVQPEVALKRVPSPTPAPKEA---VREGRPPEPTPA 2601
Query: 474 SEELLSHLRTHTALPGAEKLLAAYPGASGLGSAAAAAAAAASCHLHLPPPAAPG 527
+ S + ++ + ++ +S S+++++++++S P PA PG
Sbjct: 2602 KRKRRSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSPSPAKPG 2655
Score = 32.0 bits (71), Expect = 1.6
Identities = 33/138 (23%), Positives = 43/138 (31%), Gaps = 21/138 (15%)
Query: 165 DSRKDSGSSSVSSTSSSSSSSPGDKAGFRVP-------SAACPPFPPHGAPVSASSSSSS 217
+S + S +SS S S SSP KA R+ S+ CP P + S SS
Sbjct: 744 NSSPEMKKSRISSRRSRSLSSPRSKAKSRLSLRRSLSGSSPCPKQKSQTPPRRSRSGSSQ 803
Query: 218 PGGSRGGSPHHSDCKNGGGVGGGELDKKDQEPKPSPEPAAVSRGGGGEPGAHGGAESGAS 277
P P S + P P + SR H +SG
Sbjct: 804 PKAKSRTPPRRS--------------RSSSSPPPKQKSKTPSRQSHSSSSPHPKVKSGTP 849
Query: 278 GRKSEPPSALVGAGHVAP 295
R+ S V P
Sbjct: 850 PRQGSITSPQANEQSVTP 867
Score = 30.4 bits (67), Expect = 4.8
Identities = 42/180 (23%), Positives = 57/180 (31%), Gaps = 32/180 (17%)
Query: 144 GDSPAEDKSSFKPYSKGSGGGDSRKDSGSSSVSSTSSSSSSSPGDKAGFRVPS----AAC 199
G SP + S P + G K + + SSSS P K+ + PS ++
Sbjct: 781 GSSPCPKQKSQTPPRRSRSGSSQPKAKSRTPPRRSRSSSSPPPKQKS--KTPSRQSHSSS 838
Query: 200 PPFP--PHGAPVSASSSSSSPGGSRGGSPHHSDCKNGGGVGGGELDKKDQEPKPSPE--- 254
P P G P S +S + +P C E P PE
Sbjct: 839 SPHPKVKSGTPPRQGSITSPQANEQSVTPQRRSC---------------FESSPDPELKS 883
Query: 255 --PAAVSRGGGGEPGAHGGAESGASGRKSEPPSALVGAGHVAPVSPYKPGHSVFPLPPSS 312
P+ S G P S +S P V A +SP + HS P S
Sbjct: 884 RTPSRHSCSGSSPPRVKSSTPPRQSPSRSSSPQPKV----KAIISPRQRSHSGSSSPSPS 939
>gi|110832843 TBP-associated factor 4 [Homo sapiens]
Length = 1085
Score = 59.3 bits (142), Expect = 1e-08
Identities = 80/321 (24%), Positives = 117/321 (36%), Gaps = 78/321 (24%)
Query: 2 SDSPAGSNPRTPESSGSGSGGGG-KRPAVPAAVSLLPPADPLRQANRL------------ 48
++ G+ P P + + GGGG +RP P+ L PA P A +L
Sbjct: 79 AEGAPGAAPEPPPAGRARPGGGGPQRPGPPSPRRPLVPAGPAPPAAKLRPPPEGSAGSCA 138
Query: 49 PIRVLKMLSAHTGHLLHPEYLQPLSSTPVSPIELDAKKSPLALLAQTCSQIGKPDPPPSS 108
P+ ++A PE + P P L A+ P P P P
Sbjct: 139 PVPAAAAVAA------GPEPAPAGPAKPAGPAALAARAGP------------GPGPGP-- 178
Query: 109 KLNSVAAAANGLGAEKDPGRSA-PGAA--------------SAAAALKQLGDSPAEDKSS 153
G G PG+ A PGAA +AA A+ + + PA +
Sbjct: 179 ----------GPGPGPGPGKPAGPGAAQTLNGSAALLNSHHAAAPAVSLVNNGPA----A 224
Query: 154 FKPYSKGSGGGDSRKDSGSSSVSSTSSSSSSSPGDKAGFRVPSAACPPFPPHGAPVSASS 213
P K + G + ++ + ++ SP P+AA PP PP AP + +
Sbjct: 225 LLPLPKPAAPGTVIQTPPFVGAAAPPAPAAPSPPAAPAPAAPAAAPPPPPP--APATLAR 282
Query: 214 SSSSPGG---SRGGSPHHSDCKNGGGVGGGELDKKDQEPKPSPEPAAVSRGG-GGEPGAH 269
P G + P + +NGG G P+P PAA G G+PG
Sbjct: 283 PPGHPAGPPTAAPAVPPPAAAQNGGSAGAA----------PAPAPAAGGPAGVSGQPGPG 332
Query: 270 GGAESGASGRKSEPPSALVGA 290
A + A G K+E P +V A
Sbjct: 333 AAAAAPAPGVKAESPKRVVQA 353
Score = 48.5 bits (114), Expect = 2e-05
Identities = 112/427 (26%), Positives = 145/427 (33%), Gaps = 91/427 (21%)
Query: 114 AAAANGLGAEKDPGRSAPGAASAAAALKQLGDSPAEDKSSFKPYSKGSGGGDSRKDSGSS 173
AAAA LG G A GAA A A G A + ++ GGG R G
Sbjct: 52 AAAAGALGNHVVSGSPA-GAAGAGPAAPAEGAPGAAPEPPPAGRARPGGGGPQRP--GPP 108
Query: 174 SVSSTSSSSSSSPGDKAGFRVP----SAACPPFPPHGAPVSASSSSSSPGGSRGGSPHHS 229
S + +P A R P + +C P P A V+A + G ++ P
Sbjct: 109 SPRRPLVPAGPAP-PAAKLRPPPEGSAGSCAPVPA-AAAVAAGPEPAPAGPAKPAGPAAL 166
Query: 230 DCKNGGGVGGGELDKKDQEPKPSPEPAAVSRGGGGEPGAHGGAESGASGRKSEPPSALVG 289
+ G G G G P P P P + G G +G A S + P +LV
Sbjct: 167 AARAGPGPGPGP------GPGPGPGPGKPA-GPGAAQTLNGSAALLNSHHAAAPAVSLVN 219
Query: 290 AGHVAPV---SPYKPGHSVFPLPPSSIGYHGSIVGAYAGYPSQFVPGLDPSKSGLVGGQL 346
G A + P PG +V PP VGA A P + S
Sbjct: 220 NGPAALLPLPKPAAPG-TVIQTPP--------FVGAAA-------PPAPAAPSPPAAPAP 263
Query: 347 SGGLGLPPGKPPSSSPLTGASPPSFLQGLCRDPYCLGGYHGASHLGGSSCSTCSAHDPAG 406
+ PP PP +P T A PP PAG
Sbjct: 264 AAPAAAPP--PPPPAPATLARPPGH--------------------------------PAG 289
Query: 407 PSLKAGGYPLVYPGHPLQPAALSSSAAQAALPGHPLYTYGFMLQNEPLPHSCNWVAASGP 466
P P P P AA + +A AA P + +P P + AA+ P
Sbjct: 290 P-------PTAAPAVPPPAAAQNGGSAGAAPAPAPAAGGPAGVSGQPGPGA----AAAAP 338
Query: 467 CDKRFATSEELLSHLRTHTALPGAEKLLAAYPGASGLGSAAAAAAAAASCHLHLPPPAA- 525
A S + R A P A + LAA SG S AA+ + LP PAA
Sbjct: 339 APGVKAESPK-----RVVQAAPPAAQTLAA----SGPASTAASMVIGPTMQGALPSPAAV 389
Query: 526 -PGSPGS 531
P +PG+
Sbjct: 390 PPPAPGT 396
Score = 40.4 bits (93), Expect = 0.005
Identities = 76/300 (25%), Positives = 97/300 (32%), Gaps = 41/300 (13%)
Query: 292 HVAPVSPYKPGHSVFPLPPSSI-GYHGSIVGAYAGYPSQFVPGLDPSKSGLVGGQLSGGL 350
H+AP +P + L + G GA P++ PG P + GG
Sbjct: 42 HLAPRTPEVRAAAAGALGNHVVSGSPAGAAGAGPAAPAEGAPGAAPEPPPAGRARPGGGG 101
Query: 351 GLPPGKPPSSSPLTGASPPSFLQGLCRDP-----YCLGGYHGASHLGGSSCSTCSAHDPA 405
PG P PL A P L P C A+ G + PA
Sbjct: 102 PQRPGPPSPRRPLVPAGPAPPAAKLRPPPEGSAGSCAPVPAAAAVAAGPEPAPAGPAKPA 161
Query: 406 GPSLKA-----------GGYPLVYPGHPLQP-AALSSSAAQAALPGHPLYTYGFMLQNEP 453
GP+ A G P PG P P AA + + + A L H L N
Sbjct: 162 GPAALAARAGPGPGPGPGPGPGPGPGKPAGPGAAQTLNGSAALLNSHHAAAPAVSLVN-- 219
Query: 454 LPHSCNWVAASGPCDKRFATSEELLSHLRTHTALPGAEKLLAAYPGASGLGSAAAAAAAA 513
N AA P K A T + + AA P A S AA A A
Sbjct: 220 -----NGPAALLPLPKPAAPG----------TVIQTPPFVGAAAPPAPAAPSPPAAPAPA 264
Query: 514 ASCHLHLPPPAAPGS----PGSLSLRNPHTLGLSRYHPYGKSHLSTAGGLAVPSLPTAGP 569
A PPP AP + PG + P T + P + +AG P+ GP
Sbjct: 265 APAAAPPPPPPAPATLARPPGHPA--GPPTAAPAVPPPAAAQNGGSAGAAPAPAPAAGGP 322
Score = 38.9 bits (89), Expect = 0.013
Identities = 58/249 (23%), Positives = 85/249 (34%), Gaps = 49/249 (19%)
Query: 6 AGSNPRTPESSGSGSGGGGKRPAVPAAVSLLPPADPLRQANRLPIRVLKMLSAHTGHLLH 65
A + P G G G G +PA P A L + L ++ + +++ LL
Sbjct: 168 ARAGPGPGPGPGPGPGPGPGKPAGPGAAQTLNGSAALLNSHHAAAPAVSLVNNGPAALLP 227
Query: 66 -PEYLQPLSSTPVSPI------ELDAKKSPLALLAQTCSQIGKPDPPPSSK--------- 109
P+ P + P A SP A A P PPP+
Sbjct: 228 LPKPAAPGTVIQTPPFVGAAAPPAPAAPSPPAAPAPAAPAAAPPPPPPAPATLARPPGHP 287
Query: 110 ---------LNSVAAAANGLGAEKDP-------------GRSAPGAASAAAALKQLGDSP 147
+ AAA NG A P G+ PGAA+AA A +SP
Sbjct: 288 AGPPTAAPAVPPPAAAQNGGSAGAAPAPAPAAGGPAGVSGQPGPGAAAAAPAPGVKAESP 347
Query: 148 AEDKSSFKPYSKGSGGGDSRKDSGSSSVSSTSSSSSSSPGDKAGFRVPSAACPPFP--PH 205
+ P + + +S +ST++S P + P+A PP P P
Sbjct: 348 KRVVQAAPP---------AAQTLAASGPASTAASMVIGPTMQGALPSPAAVPPPAPGTPT 398
Query: 206 GAPVSASSS 214
G P A+ +
Sbjct: 399 GLPKGAAGA 407
>gi|4502961 alpha 1 type VII collagen precursor [Homo sapiens]
Length = 2944
Score = 58.5 bits (140), Expect = 2e-08
Identities = 75/280 (26%), Positives = 98/280 (35%), Gaps = 27/280 (9%)
Query: 100 GKPDPPPSSKLNSVAAAANGLGAEKDPGRSAPGAASAAAALKQLGDSPAEDKSSFKPYSK 159
G P PP + L A G + +PG + P +G P S +
Sbjct: 2183 GDPGPPGAPGLAGPAGPQGPSGLKGEPGETGPPGRGLTGPTGAVG-LPGPPGPSGLVGPQ 2241
Query: 160 GSGGGDSRKDSGSSSVSSTSSSSSSSPGDKAGFRVPSAACPPFPPHGAPVSASSSSSSPG 219
GS G + + +S GD+ VP + P P P + +PG
Sbjct: 2242 GSPGLPGQVGETGKPGAPGRDGASGKDGDRGSPGVPGS--PGLPGPVGPKGEPGPTGAPG 2299
Query: 220 GSRGGSPHHSDCKNG-GGVGG---GELDKKDQEPKPSPEPAAVSRGGGGEPGAHGGAESG 275
+ G P K GG+ G GE K P P G GEPG + G
Sbjct: 2300 QAVVGLPGAKGEKGAPGGLAGDLVGEPGAKGDRGLPGPRGEKGEAGRAGEPG-----DPG 2354
Query: 276 ASGRKSEP-PSALVG-AGHVAPVSPYKPGHSVFPLPPSSIGYHG--SIVGA--YAGYPSQ 329
G+K P P G G P SP PG PP G G + GA G+P Q
Sbjct: 2355 EDGQKGAPGPKGFKGDPGVGVPGSPGPPG------PPGVKGDLGLPGLPGAPGVVGFPGQ 2408
Query: 330 FVPGLDPSKSGLVGGQLSGGLGLPPGKPPSSSPLTGASPP 369
P + + G G + GL PPG+ PL PP
Sbjct: 2409 TGPRGEMGQPGPSGER---GLAGPPGREGIPGPLGPPGPP 2445
Score = 52.0 bits (123), Expect = 2e-06
Identities = 112/447 (25%), Positives = 142/447 (31%), Gaps = 85/447 (19%)
Query: 24 GKRPAVPAAVSLLPPADPLR----------QANRLPIRVLKMLSAHTGHL--LHP--EYL 69
G+R VP + LL +PLR QA+ L + +L M A L L P + +
Sbjct: 1152 GRRQHVPGVMVLLVD-EPLRGDIFSPIREAQASGLNVVMLGMAGADPEQLRRLAPGMDSV 1210
Query: 70 QPLSSTPVSPIELDAKKSPLALLAQTCSQIGKPDPPPSS----KLNSVAAAANGL----G 121
Q + P LD S LA S +P P P K GL G
Sbjct: 1211 QTFFAVDDGP-SLDQAVSGLATALCQASFTTQPRPEPCPVYCPKGQKGEPGEMGLRGQVG 1269
Query: 122 AEKDPGRSAPGAASAAAALKQLGDSPAEDKSSFKPYSKGSGGGDSRKDSGSSSVSSTSSS 181
DPG PG A G + A+ + F P + G G R + + +
Sbjct: 1270 PPGDPG--LPGRTGAPGPQGPPGSATAKGERGF-PGADGRPGSPGRAGNPGTPGAPGLKG 1326
Query: 182 SSSSPGDKAGFRVPSAACPPFPPHGAPVSASSSSSSPGGSRGGSPHHSDCKNGGGVGGGE 241
S PG + P P +PG GG G G+ G +
Sbjct: 1327 SPGLPGPRGD-----------PGERGPRGPKGEPGAPGQVIGGE--------GPGLPGRK 1367
Query: 242 LDKKDQEPKPSPEPAAVSRGGGGEPGAHGGAESGASGRKSEPPSALVGAGHVAPVSPYKP 301
D P P P G G PG G A G G + E G G +AP P P
Sbjct: 1368 GDPGPSGP-PGPRGPLGDPGPRGPPGLPGTAMKGDKGDRGERGPPGPGEGGIAPGEPGLP 1426
Query: 302 GHSVFPLPPSSIGYHGSIVGAYAGYPSQFVPGLDPSKSGLVGGQLSGGLGLP--PGKPPS 359
G P P +G P K G G G GLP PG P
Sbjct: 1427 GLPGSPGPQGPVG--------------------PPGKKGEKGDSEDGAPGLPGQPGSPGE 1466
Query: 360 SSPL--TGASPPSFLQGLC-----------RDPYCLGGYHGASHLGGSSCSTCSAHDPAG 406
P GA P +G R P G G + G P G
Sbjct: 1467 QGPRGPPGAIGPKGDRGFPGPLGEAGEKGERGPPGPAGSRGLPGVAGRP-GAKGPEGPPG 1525
Query: 407 PSLKAGGYPLVYPGHPLQPAALSSSAA 433
P+ + G PG P PA + + A
Sbjct: 1526 PTGRQG--EKGEPGRPGDPAVVGPAVA 1550
Score = 37.0 bits (84), Expect = 0.051
Identities = 69/285 (24%), Positives = 87/285 (30%), Gaps = 34/285 (11%)
Query: 100 GKPDPPPSSKLNSVAAAANGLGAEKDPGRSAPGAASAAAALKQLGDSPAEDKS---SFKP 156
GKP S N A A G + PG + L P ED + K
Sbjct: 1785 GKPGAAGPSGPNGAAGKAGDPGRDGLPGLRGEQGLPGPSGPPGLPGKPGEDGKPGLNGKN 1844
Query: 157 YSKGSGGGDSRKDSGSSSVSSTSSSSSSSPGDKAGFRVPSAACPPFPPHGAPVSASSSSS 216
G G D RK S +S G++ P P PP G P
Sbjct: 1845 GEPGDPGEDGRKGEKGDSGASGREGRDGPKGERGA---PGILGPQGPP-GLPGPVGPPGQ 1900
Query: 217 SPGGSRGGSPHHSDCKNGGGVGGGELDKKDQEPKPSPEPAAVSRGGGGEPGAHGGAESGA 276
G GG+ D GE K ++ P RG GEPG+ +
Sbjct: 1901 GFPGVPGGTGPKGD--------RGETGSKGEQGLPG------ERGLRGEPGSVPNVD--- 1943
Query: 277 SGRKSEPPSALVGAGHVAPVSPYKPGHSVFPLPPSSIGYHGSIVGAYAGYPSQFVPGLDP 336
R E A + + S P+P G G G P + P P
Sbjct: 1944 --RLLETAGIKASALREIVETWDESSGSFLPVPERRRGPKGD--SGEQGPPGKEGPIGFP 1999
Query: 337 SKSGLVGGQLSGGLGLPPG------KPPSSSPLTGASPPSFLQGL 375
+ GL G + G PPG PP S L G + GL
Sbjct: 2000 GERGLKGDRGDPGPQGPPGLALGERGPPGPSGLAGEPGKPGIPGL 2044
Score = 30.4 bits (67), Expect = 4.8
Identities = 69/264 (26%), Positives = 78/264 (29%), Gaps = 66/264 (25%)
Query: 121 GAEKDPGRSAPGAASAAAALKQLGD-SPAEDKSSFKPYSKGSGGGDSRKDSGSSSVSSTS 179
GA+ D G P GD P D P KGS G
Sbjct: 2533 GAKGDMGERGPRGLD--------GDKGPRGDNGD--PGDKGSKG---------------- 2566
Query: 180 SSSSSSPGDKAGFRVPSAACPPFPPHGAPVSASSSSSSPGGSRGGSPHHSDCKNGGGVGG 239
PGDK +P P G P +A + G P G+ G
Sbjct: 2567 -----EPGDKGSAGLPGLR-GLLGPQGQPGAAGIPGDPGSPGKDGVP---------GIRG 2611
Query: 240 GELDKKDQEPKPSPEPAAVSRGGGGEPGAHGGAE-SGASGRKSE--PPSALVGAGHVAPV 296
+ D P RG GE G G G G K E PP AGH +
Sbjct: 2612 EKGDVGFMGP----------RGLKGERGVKGACGLDGEKGDKGEAGPPGRPGLAGHKGEM 2661
Query: 297 -SPYKPGHSVFPLPPSSIGYHGSIVGAYAGYPSQFVPGLDPSKSGLVGGQLSGGLGLPPG 355
P PG S P IG G G+ Q P D + G G GG P G
Sbjct: 2662 GEPGVPGQSGAPGKEGLIGPKGD-----RGFDGQPGPKGDQGEKGERGTPGIGGFPGPSG 2716
Query: 356 K-----PPSSSPLTGASPPSFLQG 374
PP G P LQG
Sbjct: 2717 NDGSAGPPGPPGSVGPRGPEGLQG 2740
>gi|4502951 collagen type III alpha 1 preproprotein [Homo sapiens]
Length = 1466
Score = 58.2 bits (139), Expect = 2e-08
Identities = 116/465 (24%), Positives = 145/465 (31%), Gaps = 51/465 (10%)
Query: 100 GKPDPPPSSKLNSVAAAANGLGAEKDPGRSAPGAASAAAALKQLGDSPAEDKSSFKPYSK 159
G PP + G D G + P L G P E+ +P K
Sbjct: 603 GPQGPPGKNGETGPQGPPGPTGPGGDKGDTGPPGPQGLQGLPGTGGPPGENGKPGEPGPK 662
Query: 160 GSGGGDSR---KDSGSSSVSSTSSSSSSSPGDKAGFRVP------SAACPPFPPHGAPVS 210
G G K + + +PG + G P AA PP PP A
Sbjct: 663 GDAGAPGAPGGKGDAGAPGERGPPGLAGAPGLRGGAGPPGPEGGKGAAGPPGPPGAAGTP 722
Query: 211 ASSSSSSPGGSRGGSPHHSDCKNGGGVGGGELDKKDQEPKPS-----PEPAAV--SRGGG 263
G G D GG G + KD P+ P PA +G G
Sbjct: 723 GLQGMPGERGGLGSPGPKGDKGEPGGPGADGVPGKDGPRGPTGPIGPPGPAGQPGDKGEG 782
Query: 264 GEPGAHG-GAESGASGRKSE--PPSALVGAGHVAPVSPYKPGHSVFPLPPSSIGYHGSIV 320
G PG G G+ G + E PP G AP +PG P G G
Sbjct: 783 GAPGLPGIAGPRGSPGERGETGPPGPAGFPG--APGQNGEPGGKGERGAPGEKGEGGP-- 838
Query: 321 GAYAGYPSQFVPGLDPSKSGLVGGQLS----GGLGLP-----PGKPPSSSPLTGASPPSF 371
AG P P P G+ G + S G G P PG PP S+ G PS
Sbjct: 839 PGVAGPPGGSGPAGPPGPQGVKGERGSPGGPGAAGFPGARGLPG-PPGSNGNPGPPGPSG 897
Query: 372 LQGLCRDPYCLGGYHGASHLGGSSCSTCSAHDPAGPSLKAGGYPLVYPGHPLQPAALSSS 431
G P G GA G S A P P PG PL A ++ +
Sbjct: 898 SPGKDGPPGPAGN-TGAPGSPGVSGPKGDAGQPGEKGSPGAQGPPGAPG-PLGIAGITGA 955
Query: 432 AAQAALPGHPLYTYGFMLQNEPLPHSCNWVA----ASGPCDKRFATSEELLSHLRTHTAL 487
A PG P + P P + A+G +R + L L
Sbjct: 956 RGLAGPPGMP------GPRGSPGPQGVKGESGKPGANGLSGERGPPGPQGLPGLAGTAGE 1009
Query: 488 PGAEKLLAAYPGASGLGSAAAAAAAAASCHLHLPP--PAAPGSPG 530
PG + PG+ GL + + P P APG PG
Sbjct: 1010 PGRD----GNPGSDGLPGRDGSPGGKGDRGENGSPGAPGAPGHPG 1050
Score = 53.9 bits (128), Expect = 4e-07
Identities = 94/359 (26%), Positives = 114/359 (31%), Gaps = 56/359 (15%)
Query: 100 GKPDPPPSSKLNSVAAAANGLGAEKDPG-RSAPGAASAAAALKQLGDSPAEDKSSFKPYS 158
G PP + + G GA PG R PG + +P S P
Sbjct: 849 GPAGPPGPQGVKGERGSPGGPGAAGFPGARGLPGPPGS-------NGNPGPPGPSGSPGK 901
Query: 159 KGSGGGDSRKDSGSSSVSSTSSSSSSSPGDKAGFRVPSAACPPFPPHG---APVSASSSS 215
G G + S S + PG+K P A PP P A ++ +
Sbjct: 902 DGPPGPAGNTGAPGSPGVSGPKGDAGQPGEKGS---PGAQGPPGAPGPLGIAGITGARGL 958
Query: 216 SSPGGSRG--GSPHHSDCKNGGGVGGGELDKKDQEPKPSPEPAAVSRGGGGEPGAHGGAE 273
+ P G G GSP K G G ++ P P P+ G GEPG G
Sbjct: 959 AGPPGMPGPRGSPGPQGVKGESGKPGANGLSGERGP-PGPQGLPGLAGTAGEPGRDGNPG 1017
Query: 274 S-GASGRKSEP-----------PSALVGAGHVAPVSPYKP-------GHSVFPLPPSSIG 314
S G GR P P A GH P P P G S P + G
Sbjct: 1018 SDGLPGRDGSPGGKGDRGENGSPGAPGAPGHPGPPGPVGPAGKSGDRGESGPAGPAGAPG 1077
Query: 315 YHGSIVGAYAGYPSQFVPGLDPSKSGLVGGQ-LSGGLGLP--PGKPPSSSPLTGASPPSF 371
GS G P P D ++G G + G G P PG P G+ P+
Sbjct: 1078 PAGS-----RGAPGPQGPRGDKGETGERGAAGIKGHRGFPGNPGAP-------GSPGPAG 1125
Query: 372 LQGLCRDPYCLGGYHGASHLGGSSCSTCSAH-DPAGPSLKAGGY----PLVYPGHPLQP 425
QG P G G S H P GP G PGHP QP
Sbjct: 1126 QQGAIGSPGPAGPRGPVGPSGPPGKDGTSGHPGPIGPPGPRGNRGERGSEGSPGHPGQP 1184
Score = 47.4 bits (111), Expect = 4e-05
Identities = 88/331 (26%), Positives = 116/331 (35%), Gaps = 26/331 (7%)
Query: 98 QIGKPDPPPSSKLNSVAAAANGLGAEKDPG-RSAPGAASAAAALKQLG--DSPAEDKSSF 154
+ G P + L A +G PG R PG AA A G S +
Sbjct: 277 ETGAPGLKGENGLPGENGAPGPMGPRGAPGERGRPGLPGAAGARGNDGARGSDGQPGPPG 336
Query: 155 KPYSKGSGGGDSRKDSGSSSVSSTSSSSSSSPGDKAGFRVPSAACPPFPP--HGAP---- 208
P + G G K + S S+ + G+ A PP PP +G+P
Sbjct: 337 PPGTAGFPGSPGAKGEVGPAGSPGSNGAPGQRGEPGPQGHAGAQGPPGPPGINGSPGGKG 396
Query: 209 -VSASSSSSSPG--GSRGG-SPHHSDCKNGGGVGGGELDKKDQEPKPSPEPAAVSRGGGG 264
+ + +PG G+RG P ++ G G GE K + +P P G G
Sbjct: 397 EMGPAGIPGAPGLMGARGPPGPAGANGAPGLRGGAGEPGKNGAKGEPGPRGERGEAGIPG 456
Query: 265 EPGAHGGAESGASGRKSEP-PSALVGAG--HVAPVSPYKPGHSVFPLPPSSIGYHGSIVG 321
PGA G E G G EP + L GA AP G + P G G+
Sbjct: 457 VPGAKG--EDGKDGSPGEPGANGLPGAAGERGAPGFRGPAGPNGIPGEKGPAGERGAPGP 514
Query: 322 A----YAGYPSQ-FVPGLDPSKSGLVGGQLSGGLGLPPGKPPSSSPLTGASPPSFLQGLC 376
A AG P + VPG P G+ G G PG PP S +G P G
Sbjct: 515 AGPRGAAGEPGRDGVPG-GPGMRGMPGSPGGPGSDGKPG-PPGSQGESGRPGPPGPSGPR 572
Query: 377 RDPYCLGGYHGASHLGGSSCSTCSAHDPAGP 407
P + G+ G G+ P GP
Sbjct: 573 GQPGVM-GFPGPKGNDGAPGKNGERGGPGGP 602
Score = 46.2 bits (108), Expect = 8e-05
Identities = 86/366 (23%), Positives = 113/366 (30%), Gaps = 79/366 (21%)
Query: 100 GKPDPP-----PSSKLNSVAAAANG----LGAEKDPGRSAPGAASAAAALKQLGDSPAED 150
G P PP P K A G +GA PG P A+ A L+ P ++
Sbjct: 381 GPPGPPGINGSPGGKGEMGPAGIPGAPGLMGARGPPG---PAGANGAPGLRGGAGEPGKN 437
Query: 151 KSSFKPYSKGSGG-----------GDSRKDSGSSSVSSTSSSSSSSPGDKAGFRVPSAAC 199
+ +P +G G G+ KD + ++ GFR P+
Sbjct: 438 GAKGEPGPRGERGEAGIPGVPGAKGEDGKDGSPGEPGANGLPGAAGERGAPGFRGPAG-- 495
Query: 200 PPFPPHGAP----VSASSSSSSPGGSRG--GSPHHSDCKNGGGV-------GGGELDKKD 246
P+G P + + P G RG G P G G+ GG D K
Sbjct: 496 ----PNGIPGEKGPAGERGAPGPAGPRGAAGEPGRDGVPGGPGMRGMPGSPGGPGSDGKP 551
Query: 247 QEP-------KPSP--------EPAAVS----RGGGGEPGAHGGAESGASGRKSEPPSAL 287
P +P P +P + +G G PG +G PP
Sbjct: 552 GPPGSQGESGRPGPPGPSGPRGQPGVMGFPGPKGNDGAPGKNGERGGPGGPGPQGPPGKN 611
Query: 288 VGAGHVAPVSPYKPGHSVFPL-PPSSIGYHGSIVGAYAGYPSQFVPGLDPSKSGLVGGQL 346
G P P PG PP G G + G P + +P G G
Sbjct: 612 GETGPQGPPGPTGPGGDKGDTGPPGPQGLQG--LPGTGGPPGENGKPGEPGPKGDAGAP- 668
Query: 347 SGGLGLPPGKPPSSSPLTGASPPSFLQGLCRDPYCLGGYHGASHLGGSSCSTCSAHDPAG 406
G P GK + +P P GL P GG GG A P G
Sbjct: 669 ----GAPGGKGDAGAPGERGPP-----GLAGAPGLRGGAGPPGPEGGK-----GAAGPPG 714
Query: 407 PSLKAG 412
P AG
Sbjct: 715 PPGAAG 720
Score = 42.0 bits (97), Expect = 0.002
Identities = 39/128 (30%), Positives = 48/128 (37%), Gaps = 19/128 (14%)
Query: 247 QEPKPSPEPAAVSRGGGGEPGAHGGAESGASGRKSEPPSALVGAGHVAPVSP--YKPGHS 304
Q PK P P + G G+PG G + G+ G P G P P Y P +
Sbjct: 105 QGPKGDPGPPGIP-GRNGDPGIPG--QPGSPGSPGPP-----GICESCPTGPQNYSPQYD 156
Query: 305 VFPLPPSSIGYHGSIVGAYAGYPSQFVPGLDPSK---SGLVGGQLSGGLGLPPGKPPSSS 361
+ + G VG AGYP P P SG G S G PPG+P +
Sbjct: 157 SYDVKS------GVAVGGLAGYPGPAGPPGPPGPPGTSGHPGSPGSPGYQGPPGEPGQAG 210
Query: 362 PLTGASPP 369
P PP
Sbjct: 211 PSGPPGPP 218
>gi|57864582 hornerin [Homo sapiens]
Length = 2850
Score = 57.8 bits (138), Expect = 3e-08
Identities = 82/322 (25%), Positives = 118/322 (36%), Gaps = 30/322 (9%)
Query: 107 SSKLNSVAAAANGLGAEKDPGRSAPGAASAAAALKQLG--DSPAEDKSSFKPYSKGSGGG 164
SS +S + +G G+ + G S G+ S + G +S + SS+ P+ GSG
Sbjct: 509 SSAGSSSSYGQHGSGSRQSLGHSRHGSGSGQSPSPSRGRHESGSRQSSSYGPHGYGSGRS 568
Query: 165 DSR--KDSGSSSVSSTSSSSSSSPGDKAGFRVPSAACPPFPPHGAPVSASSSSSSPGGSR 222
SR +SGS S S S G +G+ ++ HG S S SSS G
Sbjct: 569 SSRGPYESGSGHSSGLGHQESRS-GQSSGYGQHGSSSGHSSTHGQHGSTSGQSSS-CGQH 626
Query: 223 GGSPHHSDCKNGGGVGGGELDKKDQEPKPSPEPAAVSRGGG--GEPGAHGGAESGASGRK 280
G + S G G + + Q+ S + + R G G ++G SG+
Sbjct: 627 GATSGQSSSHGQHGSGSSQSSRYGQQGSGSGQSPSRGRHGSDFGHSSSYGQHGSGSGWSS 686
Query: 281 SEPPSALVGAGHVAPVSPYKPGHSVFPLPPSSIGYHGSIVGAYAGYPSQFVPGLDPSKSG 340
S P V +G + GH S HGS +GY S+S
Sbjct: 687 SNGPHGSV-SGQSSGF-----GHKSGSGQSSGYSQHGSGSSHSSGYRKHGSRSGQSSRSE 740
Query: 341 LVGGQLSGGLGLPPGKPPSSSPL----------TGASPPSFLQGLCRDPYCLGGYHGASH 390
G S GL G+ S S +G SP G G HG+
Sbjct: 741 QHGS--SSGLSSSYGQHGSGSHQSSGHGRQGSGSGHSPSRVRHGSSSGHSSSHGQHGS-- 796
Query: 391 LGGSSCSTCSAHDPAGPSLKAG 412
G+SCS+ H +G +G
Sbjct: 797 --GTSCSSSCGHYESGSGQASG 816
Score = 56.6 bits (135), Expect = 6e-08
Identities = 85/341 (24%), Positives = 114/341 (33%), Gaps = 16/341 (4%)
Query: 107 SSKLNSVAAAANGLGAEKDPGRSAPGAASAAAALKQLG--DSPAEDKSSFKPYSKGSGGG 164
SS +S + +G G+ + G G+ S + G S + SS+ PY GSG
Sbjct: 1915 SSSGSSSSYGQHGSGSRQSLGHGQHGSGSGQSPSPSRGRHGSGSGQSSSYGPYGSGSGWS 1974
Query: 165 DSR--KDSGSSSVSSTSSSSSSSPGDKAGFRVPSAACPPFPPHGAPVSASSSSSSPGGSR 222
SR +SGS S S S G +G+ ++ HG SAS SSS G
Sbjct: 1975 SSRGPYESGSGHSSGLGHRESRS-GQSSGYGQHGSSSGHSSTHGQHGSASGQSSS-CGQH 2032
Query: 223 GGSPHHSDCKNGGGVGGGELDKKDQEPKPSPE-PAAVSRGGGGEPGAHGGAESGASGRKS 281
G S S G G + ++ S + P RG G G SGR S
Sbjct: 2033 GASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQSPGHGQRGSGSRQSPSYGRHGSGSGRSS 2092
Query: 282 EPPSALVGAGHVAPVSPYKPGHSVFPLPPSSIGYHGSIVGAYAGYPSQFVPGLDPSKSGL 341
G G + ++ SS HGS G +GY Q S G
Sbjct: 2093 SSGQHGPGLGESSGFGHHESSSG----QSSSYSQHGSGSGHSSGY-GQHGSRSGQSSRGE 2147
Query: 342 VGGQLSGGLGL--PPGKPPSSSPLTGASPPSFLQGLCRDPYCLGGYHGASHLGGSSCSTC 399
G SG G S G R + G H +SH G S
Sbjct: 2148 RHGSSSGSSSRYGQHGSGSRQSSGHGRQGSGSGHSPSRGRHGSGSGHSSSH--GQHGSGS 2205
Query: 400 SAHDPAGPSLKAGGYPLVYPGHPLQPAALSSSAAQAALPGH 440
GP G+ V+ H S+ + + GH
Sbjct: 2206 GRSSSRGPYESRSGHSSVFGQHESGSGHSSAYSQHGSGSGH 2246
Score = 54.7 bits (130), Expect = 2e-07
Identities = 60/225 (26%), Positives = 82/225 (36%), Gaps = 11/225 (4%)
Query: 107 SSKLNSVAAAANGLGAEKDPGRSAPGAASAAAALKQLG--DSPAEDKSSFKPYSKGSGGG 164
SS +S + +G G+ + G G+ S + G S + SS+ PY GSG
Sbjct: 2385 SSSGSSSSYGQHGSGSRQSLGHGQHGSGSGQSPSPSRGRHGSGSGQSSSYSPYGSGSGWS 2444
Query: 165 DSR--KDSGSSSVSSTSSSSSSSPGDKAGFRVPSAACPPFPPHGAPVSASSSSSSPGGSR 222
SR +SGS S S S G +G+ ++ HG S S SSS G
Sbjct: 2445 SSRGPYESGSGHSSGLGHRESRS-GQSSGYGQHGSSSGHSSTHGQHGSTSGQSSS-CGQH 2502
Query: 223 GGSPHHSDCKNGGGVGGGELDKKDQEPKPSPE-PAAVSRGGGGEPGAHGGAESGASGRKS 281
G S S G G + ++ S + P RG G G SGR S
Sbjct: 2503 GASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQSPGHGQRGSGSRQSPSYGRHGSGSGRSS 2562
Query: 282 EPPSALVGAGHVAPVSPYKPGHSVFPLPPSSIGYHGSIVGAYAGY 326
G G + ++ SS HGS G +GY
Sbjct: 2563 SSGQHGSGLGESSGFGHHESSSG----QSSSYSQHGSGSGHSSGY 2603
Score = 51.2 bits (121), Expect = 3e-06
Identities = 85/331 (25%), Positives = 116/331 (35%), Gaps = 45/331 (13%)
Query: 118 NGLGAEKDPGRSAPGAASAAAALKQLGDSPAEDKSSFKPYSKGSGGGDSRKDSGSSSVSS 177
+G G+ + PG G+ S G SP S+ + GSG S GS S S
Sbjct: 883 HGSGSGQSPGHGQRGSGS--------GQSP-----SYGRHGSGSGRSSSSGRHGSGSGQS 929
Query: 178 TSSSSSSSPGDKAGFR---VPSAACPPFPPHGAPVSASSSSSSPGGSRGGSPHHSDCKNG 234
+ SS G +G+ S + HG+ SS S G S G S + +G
Sbjct: 930 SGFGHKSSSGQSSGYTQHGSGSGHSSSYEQHGSRSGQSSRSEQHGSSSGSSSSYGQHGSG 989
Query: 235 G--GVGGGELDKKDQEPKPSPEPAAVSRG-GGGEPGAHGGAESGASGRKSEPP-----SA 286
+G G+ + SP P+ G G G+ ++G SG+ S P
Sbjct: 990 SRQSLGHGQHGSGSGQ---SPSPSRGRHGSGSGQSSSYGPYRSGSGWSSSRGPYESGSGH 1046
Query: 287 LVGAGHVAPVSPYKPG---HSVFPLPPSSIGYHGSIVGAYAGYPSQFVPGLDPSKSGLVG 343
G GH S G H S+ G HGS G + S G G
Sbjct: 1047 SSGLGHRESRSGQSSGYGQHGSSSGHSSTHGQHGSTSGQSSSCGQHGASSGQSSSHGQHG 1106
Query: 344 GQLSGGLGLPPGKPPSSSPLTGASPPSFLQGLCRDPYCLGGYHGASHLGGSSCSTCSAHD 403
S G G+ S S G SP +G G HG+ GS S+ S
Sbjct: 1107 SGSSQSSGY--GRQGSGS---GQSPGHGQRGSGSRQSPSYGRHGS----GSGRSSSSGQH 1157
Query: 404 PAGPSLKAGGYPLVYPGHPLQPAALSSSAAQ 434
+G +G GH + SSS +Q
Sbjct: 1158 GSGLGESSGF------GHHESSSGQSSSYSQ 1182
Score = 48.1 bits (113), Expect = 2e-05
Identities = 57/232 (24%), Positives = 78/232 (33%), Gaps = 14/232 (6%)
Query: 95 TCSQIGKPDPPPSSKLNSVAAAANGLGAEKDPGRSAPGAASAAAALKQLGDSPAEDKSSF 154
T Q D SS S + G G+ + G GA S + + S + SS+
Sbjct: 1316 TSGQSSTFDQEGSSTGQSSSYGHRGSGSSQSSGYGRHGAGSGQSPSRGRHGSGSGHSSSY 1375
Query: 155 KPYSKGSGGGDSRKDSGSSSVSSTSSSSSSSPGDKAGFRVPSAACPPFPPHGAPVSASSS 214
+ GSG S SS + S SS G S+ C HG+ S SS
Sbjct: 1376 GQHGSGSGW------SSSSGRHGSGSGQSSGFGHHESSSWQSSGC---TQHGSG-SGHSS 1425
Query: 215 SSSPGGSRGGSPHHSDCKNGGGVGGGELDKKDQEPKPSPEPAAVSRGGGGEPGAHGGAES 274
S GSR G + + + S G G P G
Sbjct: 1426 SYEQHGSRSGQSSRGERHGSSSGSSSSYGQHGSGSRQSLGHGQHGSGSGQSPSPSRGRHG 1485
Query: 275 GASGRKSEPPSALVGAGHVAPVSPYKPGHSVFPLPPSSIGYHGSIVGAYAGY 326
SG+ S G+G + PY+ G S S +G+ S G +GY
Sbjct: 1486 SGSGQSSSYSPYGSGSGWSSSRGPYESGSS----HSSGLGHRESRSGQSSGY 1533
Score = 46.2 bits (108), Expect = 8e-05
Identities = 66/253 (26%), Positives = 91/253 (35%), Gaps = 31/253 (12%)
Query: 119 GLGAEKDPGRSAPGAASAAAALKQLGDSPAEDKSSFKPYSKGSG--GGDSRKDSGSSSVS 176
G G+ P R G++S ++ S SS Y GSG G + +SGS
Sbjct: 769 GSGSGHSPSRVRHGSSSGHSSSHGQHGSGTSCSSSCGHYESGSGQASGFGQHESGSGQGY 828
Query: 177 STSSSSSSSPGDKAGFRVPSAACPPFPPHGAPVSASSSSSSPGGSRGGSPHHSDCKNGGG 236
S S+S + S H +SS SS G + HH+ + G
Sbjct: 829 SQHGSASGHFSSQGRHGSTSGQSSSSGQH----DSSSGQSSSYGQHESASHHASGRGRHG 884
Query: 237 VGGGELDKKDQEPKPSPEPAAVSRGGGG-----EPGAHG---GAESG-----ASGRKSEP 283
G G+ Q S + + R G G G HG G SG +SG+ S
Sbjct: 885 SGSGQSPGHGQRGSGSGQSPSYGRHGSGSGRSSSSGRHGSGSGQSSGFGHKSSSGQSSGY 944
Query: 284 PSALVGAGHVAPVSPY--KPGHSVFPLPPSSIGYHGSIVGAYAGYPSQFVPGLDPSKSGL 341
G+GH + + + G S S HGS G+ + Y Q G S+ L
Sbjct: 945 TQHGSGSGHSSSYEQHGSRSGQS------SRSEQHGSSSGSSSSY-GQHGSG---SRQSL 994
Query: 342 VGGQLSGGLGLPP 354
GQ G G P
Sbjct: 995 GHGQHGSGSGQSP 1007
Score = 45.4 bits (106), Expect = 1e-04
Identities = 61/253 (24%), Positives = 93/253 (36%), Gaps = 39/253 (15%)
Query: 112 SVAAAANGLGAEKDPGRSAPGAASAAAALKQLGDSPAEDKSSFKPYSKGSGGGDSRKDSG 171
S ++ +G G+ + G ++ ++ Q G S + SS++ + SG + G
Sbjct: 916 SSSSGRHGSGSGQSSGFGHKSSSGQSSGYTQHG-SGSGHSSSYEQHGSRSGQSSRSEQHG 974
Query: 172 SSSVSSTSSSSSSSPGDKA---GFRVPSAACPPFPPHGAPVSASSSSSSPGGSRGGS--- 225
SSS SS+S S ++ G + P P G S S SSS G R GS
Sbjct: 975 SSSGSSSSYGQHGSGSRQSLGHGQHGSGSGQSPSPSRGRHGSGSGQSSSYGPYRSGSGWS 1034
Query: 226 ----PHHSDCKNGGGVG------------------GGELDKKDQEPKPSPEPAAVSRGG- 262
P+ S + G+G G Q S + ++ + G
Sbjct: 1035 SSRGPYESGSGHSSGLGHRESRSGQSSGYGQHGSSSGHSSTHGQHGSTSGQSSSCGQHGA 1094
Query: 263 -GGEPGAHGGAESGAS-----GRKSEPPSALVGAGHVAPVSPYKPG---HSVFPLPPSSI 313
G+ +HG SG+S GR+ G G S P H SS
Sbjct: 1095 SSGQSSSHGQHGSGSSQSSGYGRQGSGSGQSPGHGQRGSGSRQSPSYGRHGSGSGRSSSS 1154
Query: 314 GYHGSIVGAYAGY 326
G HGS +G +G+
Sbjct: 1155 GQHGSGLGESSGF 1167
Score = 45.4 bits (106), Expect = 1e-04
Identities = 77/315 (24%), Positives = 109/315 (34%), Gaps = 51/315 (16%)
Query: 107 SSKLNSVAAAANGLGAEKDPGRSAPGAASAAAALKQLG--DSPAEDKSSFKPYSKGSGGG 164
SS +S + +G G+ + G G+ S + G S + SS+ PY GSG
Sbjct: 1445 SSSGSSSSYGQHGSGSRQSLGHGQHGSGSGQSPSPSRGRHGSGSGQSSSYSPYGSGSGWS 1504
Query: 165 DSRK--DSGSSSVSS------------------TSSSSSSSPGDKAGFRVPSAAC----- 199
SR +SGSS S +SS SS+ G S++C
Sbjct: 1505 SSRGPYESGSSHSSGLGHRESRSGQSSGYGQHGSSSGHSSTHGQHGSTSGQSSSCGQHGA 1564
Query: 200 -----PPFPPHGAPVSASSSSSSPGGSRGGSPHHSDCKNGGGVGGGELDKKDQEPKPSPE 254
HG+ S SS G G SP H G G + + S
Sbjct: 1565 SSGQSSSHGQHGSGSSQSSGYGRQGSGSGQSPGHGQ----RGSGSRQSPSYGRHGSGSGR 1620
Query: 255 PAAVSRGGGGEPGAHG-GAESGASGRKSEPPSALVGAGHVAPVSPY--KPG-------HS 304
++ + G G + G G +SG+ S G+GH + + + G H
Sbjct: 1621 SSSSGQHGSGLGESSGFGHHESSSGQSSSYSQHGSGSGHSSGYGQHGSRSGQSSRGERHG 1680
Query: 305 VFPLPPSSIGYHGSIVGAYAGYPSQ-FVPGLDPSK----SGLVGGQLSGGLGLPPGKPPS 359
S G HGS +G+ Q G PS+ SGL G G G+ S
Sbjct: 1681 SSSRSSSRYGQHGSGSRQSSGHGRQGSGSGQSPSRGRHGSGLGHSSSHGQHGSGSGRSSS 1740
Query: 360 SSPLTGASPPSFLQG 374
P S S + G
Sbjct: 1741 RGPYESRSGHSSVFG 1755
Score = 44.7 bits (104), Expect = 2e-04
Identities = 68/265 (25%), Positives = 92/265 (34%), Gaps = 28/265 (10%)
Query: 107 SSKLNSVAAAANGLGAEKDPGRSAPGAASAAAALKQLGDSPAEDKSSFKPYSKGSGG--- 163
S S G G+ + P R G+ ++ S + SS PY SG
Sbjct: 1694 SGSRQSSGHGRQGSGSGQSPSRGRHGSGLGHSSSHGQHGSGSGRSSSRGPYESRSGHSSV 1753
Query: 164 -GDSRKDSGSSSVSSTSSSSS----------SSPGDKAGFRVPSAACPPFPPHGAPVSAS 212
G SG SS S S S S+ G + F ++ HG S S
Sbjct: 1754 FGQHESGSGHSSAYSQHGSGSGHFCSQGQHGSTSGQSSTFDQEGSSTGQSSSHGQHGSGS 1813
Query: 213 SSSSSPGGSRGGSPHHSDCKNGGGVGGGELDKKDQEPKPSPEPAAVSRGGGGEPGAHG-G 271
S SSS G +G S + G G G Q S ++ R G G + G G
Sbjct: 1814 SQSSS-YGQQGSGSGQSPSRGRHGSGSGHSSSYGQHGSGSGWSSSSGRHGSGSGQSSGFG 1872
Query: 272 AESGASGRKSEPPSALVGAGHVAPVSPY--KPGHSVFPLPPSSIGYHGSIVGAYAGYPSQ 329
+S + S G+GH + + + G S S HGS G+ + Y Q
Sbjct: 1873 HHESSSWQSSGYTQHGSGSGHSSSYEQHGSRSGQS------SRGEQHGSSSGSSSSY-GQ 1925
Query: 330 FVPGLDPSKSGLVGGQLSGGLGLPP 354
G S+ L GQ G G P
Sbjct: 1926 HGSG---SRQSLGHGQHGSGSGQSP 1947
Score = 43.9 bits (102), Expect = 4e-04
Identities = 72/289 (24%), Positives = 103/289 (35%), Gaps = 35/289 (12%)
Query: 111 NSVAAAANGLGAEKDPGRSAPGAASAAAALKQLGDSPAEDKSSFKPYSKGSGGGDSRKDS 170
+S + +G G+ + R + S +++ +S + S++ + GSG S+
Sbjct: 2194 HSSSHGQHGSGSGRSSSRGPYESRSGHSSVFGQHESGSGHSSAYSQHGSGSGHFCSQGQH 2253
Query: 171 GSSS-VSSTSSSSSSSPGDKAGFRVPSAACPPFPPHGAPVSASSSSSSPGGSRGGSPHHS 229
GS+S SST SS G + HG S SS SSS G +G S
Sbjct: 2254 GSTSGQSSTFDQEGSSTGQSSS-------------HGQHGSGSSQSSS-YGQQGSGSGQS 2299
Query: 230 DCKNGGGVGGGELDKKDQEPKPSPEPAAVSRGGGGEPGAHG-GAESGASGRKSEPPSALV 288
+ G G G Q S ++ R G G + G G +S + S
Sbjct: 2300 PSRGRHGSGSGHSSSYGQHGSGSGWSSSSGRHGSGSGQSSGFGHHESSSWQSSGYTQHGS 2359
Query: 289 GAGHVAPVSPY--KPG-------HSVFPLPPSSIGYHGSIVGAYAGYPSQFVPGLDPSKS 339
G+GH + + + G H SS G HGS G G S S
Sbjct: 2360 GSGHSSSYEQHGSRSGQSSRGERHGSSSGSSSSYGQHGS------GSRQSLGHGQHGSGS 2413
Query: 340 GLVGGQLSGGLGLPPGKPPSSSPLTGASPPSFLQGLCRDPYCLGGYHGA 388
G G G G+ S SP S S +G PY G H +
Sbjct: 2414 GQSPSPSRGRHGSGSGQSSSYSPYGSGSGWSSSRG----PYESGSGHSS 2458
Score = 43.9 bits (102), Expect = 4e-04
Identities = 57/239 (23%), Positives = 80/239 (33%), Gaps = 28/239 (11%)
Query: 95 TCSQIGKPDPPPSSKLNSVAAAANGLGAEKDPGRSAPGAASAAAALKQLGDSPAEDKSSF 154
T Q D SS S + +G G+ + G+ S + + S + SS+
Sbjct: 2256 TSGQSSTFDQEGSSTGQSSSHGQHGSGSSQSSSYGQQGSGSGQSPSRGRHGSGSGHSSSY 2315
Query: 155 KPYSKGSGGGDSRKDSGSSSVSST-----SSSSSSSPGDKAGFRVPSAACPPFPPHGAPV 209
+ GSG S GS S S+ SSS S G + HG+
Sbjct: 2316 GQHGSGSGWSSSSGRHGSGSGQSSGFGHHESSSWQSSG--------------YTQHGSG- 2360
Query: 210 SASSSSSSPGGSRGGSPHHSDCKNGGGVGGGELDKKDQEPKPSPEPAAVSRGGGGEPGAH 269
S SSS GSR G + + + S G G P
Sbjct: 2361 SGHSSSYEQHGSRSGQSSRGERHGSSSGSSSSYGQHGSGSRQSLGHGQHGSGSGQSPSPS 2420
Query: 270 GGAESGASGRKSEPPSALVGAGHVAPVSPYK--PGHSVFPLPPSSIGYHGSIVGAYAGY 326
G SG+ S G+G + PY+ GHS S +G+ S G +GY
Sbjct: 2421 RGRHGSGSGQSSSYSPYGSGSGWSSSRGPYESGSGHS------SGLGHRESRSGQSSGY 2473
Score = 43.1 bits (100), Expect = 7e-04
Identities = 82/345 (23%), Positives = 116/345 (33%), Gaps = 43/345 (12%)
Query: 93 AQTCSQIGKPDPPPSSKLNSVAAAANGLGAEKDPGRSAPGAASAAAALKQLGDSPAEDKS 152
+ +C Q G SS +G G+ + G+ S + + S S
Sbjct: 620 SSSCGQHGATSGQSSSH------GQHGSGSSQSSRYGQQGSGSGQSPSRGRHGSDFGHSS 673
Query: 153 SFKPYSKGSGGGDSRKDSGSSSVSSTSSSSSSSPGDKAGFR---VPSAACPPFPPHGAPV 209
S+ + GSG S GS S S+ S G +G+ S+ + HG+
Sbjct: 674 SYGQHGSGSGWSSSNGPHGSVSGQSSGFGHKSGSGQSSGYSQHGSGSSHSSGYRKHGSRS 733
Query: 210 SASSSS---------SSPGGSRGGSPHHSDCKNGGGVGGGELDKKDQEPKPSPEPAAVSR 260
SS S SS G G H S G G G + + S ++ +
Sbjct: 734 GQSSRSEQHGSSSGLSSSYGQHGSGSHQSSGHGRQGSGSGHSPSRVRHGSSSGHSSSHGQ 793
Query: 261 GGGGE--PGAHGGAESGASGRKSEPPSALVGAGHVAPVSPYKPGHSVFPLPPSSIGYHGS 318
G G + G ESG SG+ S G+G GH SS G HGS
Sbjct: 794 HGSGTSCSSSCGHYESG-SGQASGFGQHESGSGQGYSQHGSASGHF------SSQGRHGS 846
Query: 319 IVG---------AYAGYPSQFVPGLDPSKSGLVGGQLSGGLGLPPGKPPSSSPLTGASPP 369
G + +G S + S G+ G G PG S +G SP
Sbjct: 847 TSGQSSSSGQHDSSSGQSSSYGQHESASHHASGRGRHGSGSGQSPGHGQRGSG-SGQSPS 905
Query: 370 SFLQGLCRDPYCLGGYHGASHLGGSSCSTCSAHDPAGPSLKAGGY 414
G G HG+ GS S+ H + S ++ GY
Sbjct: 906 YGRHGSGSGRSSSSGRHGS----GSGQSSGFGHKSS--SGQSSGY 944
Score = 43.1 bits (100), Expect = 7e-04
Identities = 73/282 (25%), Positives = 97/282 (34%), Gaps = 44/282 (15%)
Query: 107 SSKLNSVAAAANGLGAEKDPGRSAPGAASAAAALKQLGDSPAEDKSSFKPYSKGSGGGDS 166
S +S +G G GR G+ ++ +S + S + + GSG S
Sbjct: 1839 SGHSSSYGQHGSGSGWSSSSGRHGSGSGQSSGFGHH--ESSSWQSSGYTQHGSGSGHSSS 1896
Query: 167 RKDSGSSSVSST-------SSSSSSSPGDKA---------GFRVPSAACPPFPPHGAPVS 210
+ GS S S+ SS SSSS G G + P P G S
Sbjct: 1897 YEQHGSRSGQSSRGEQHGSSSGSSSSYGQHGSGSRQSLGHGQHGSGSGQSPSPSRGRHGS 1956
Query: 211 ASSSSSSPG---------GSRG----GSPH-----HSDCKNGGGVGGGELDKKDQEPKPS 252
S SSS G SRG GS H H + ++G G G+
Sbjct: 1957 GSGQSSSYGPYGSGSGWSSSRGPYESGSGHSSGLGHRESRSGQSSGYGQHGSSSGHSSTH 2016
Query: 253 PEPAAVSRGGGGEPGAHGGA--ESGASGRKSEPPSALVGAGHVAPVSPYKPGH---SVFP 307
+ + S G G HG + +S + G+ S G G S PGH
Sbjct: 2017 GQHGSAS-GQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQSPGHGQRGSGS 2075
Query: 308 LPPSSIGYHGSIVGAYAGYPSQFVPGLDPSKSGLVGGQLSGG 349
S G HGS G + Q PGL S SG + S G
Sbjct: 2076 RQSPSYGRHGSGSGR-SSSSGQHGPGLGES-SGFGHHESSSG 2115
Score = 42.4 bits (98), Expect = 0.001
Identities = 57/234 (24%), Positives = 86/234 (36%), Gaps = 18/234 (7%)
Query: 107 SSKLNSVAAAANGLGAEKDPGRSAPGAASAAAALKQLGDSPAEDKSSFKPYSKGS--GGG 164
SS S + + +G G+ G G+ S ++ + S + S + + GS G
Sbjct: 1172 SSSGQSSSYSQHGSGSGHSSGYGQHGSRSGQSSRGERHGSSSGSSSHYGQHGSGSRQSSG 1231
Query: 165 DSRKDSGSSSVSS-----TSSSSSSSPGDKAGFRVPSAACPPFPPHGAPVSA-----SSS 214
R+ SGS S + SSS G S++ P+ S S S
Sbjct: 1232 HGRQGSGSGHSPSRGRHGSGLGHSSSHGQHGSGSGRSSSRGPYESRSGHSSVFGQHESGS 1291
Query: 215 SSSPGGSRGGSPHHSDCKNGG-GVGGGELDKKDQEPKPSPEPAAVSRGGGGEPGAHGGAE 273
S S+ GS C G G G+ DQE + + ++ G G + G
Sbjct: 1292 GHSSAYSQHGSGSGHFCSQGQHGSTSGQSSTFDQEGSSTGQSSSYGHRGSGSSQSSGYGR 1351
Query: 274 SGA-SGRKSEPPSALVGAGHVAPVSPYKPGHSVFPLPPSSIGYHGSIVGAYAGY 326
GA SG+ G+GH + + G SS G HGS G +G+
Sbjct: 1352 HGAGSGQSPSRGRHGSGSGHSSSYGQHGSGSGW----SSSSGRHGSGSGQSSGF 1401
Score = 42.0 bits (97), Expect = 0.002
Identities = 77/324 (23%), Positives = 111/324 (34%), Gaps = 51/324 (15%)
Query: 98 QIGKPDPPPSSKLNSVAAAANGLGAEKDPGRSAPGAASAAAALKQLG--DSPAEDKSSFK 155
Q + + SS +S + +G G+ + G G+ S + G S + SS+
Sbjct: 966 QSSRSEQHGSSSGSSSSYGQHGSGSRQSLGHGQHGSGSGQSPSPSRGRHGSGSGQSSSYG 1025
Query: 156 PYSKGSGGGDSRK--DSGSSSVSS------------------TSSSSSSSPGDKAGFRVP 195
PY GSG SR +SGS S +SS SS+ G
Sbjct: 1026 PYRSGSGWSSSRGPYESGSGHSSGLGHRESRSGQSSGYGQHGSSSGHSSTHGQHGSTSGQ 1085
Query: 196 SAAC----------PPFPPHGAPVSASSSSSSPGGSRGGSPHHSDCKNGGGVGGGELDKK 245
S++C HG+ S SS G G SP H G G +
Sbjct: 1086 SSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQSPGHGQ----RGSGSRQSPSY 1141
Query: 246 DQEPKPSPEPAAVSRGGGGEPGAHG-GAESGASGRKSEPPSALVGAGHVAPVSPY--KPG 302
+ S ++ + G G + G G +SG+ S G+GH + + + G
Sbjct: 1142 GRHGSGSGRSSSSGQHGSGLGESSGFGHHESSSGQSSSYSQHGSGSGHSSGYGQHGSRSG 1201
Query: 303 -------HSVFPLPPSSIGYHGSIVGAYAGYPSQ-FVPGLDPSK----SGLVGGQLSGGL 350
H S G HGS +G+ Q G PS+ SGL G
Sbjct: 1202 QSSRGERHGSSSGSSSHYGQHGSGSRQSSGHGRQGSGSGHSPSRGRHGSGLGHSSSHGQH 1261
Query: 351 GLPPGKPPSSSPLTGASPPSFLQG 374
G G+ S P S S + G
Sbjct: 1262 GSGSGRSSSRGPYESRSGHSSVFG 1285
Score = 40.8 bits (94), Expect = 0.004
Identities = 52/212 (24%), Positives = 75/212 (35%), Gaps = 31/212 (14%)
Query: 95 TCSQIGKPDPPPSSKLNSVAAAANGLGAEKDPGRSAPGAASAAAALKQLGDSPAEDKSSF 154
T Q D SS S + +G G+ + G+ S G SP+ +
Sbjct: 1786 TSGQSSTFDQEGSSTGQSSSHGQHGSGSSQSSSYGQQGSGS--------GQSPSRGR--- 1834
Query: 155 KPYSKGSGGGDSRKDSGSSSV-SSTSSSSSSSPGDKAGFRVPSAACPPFPPHGAPVSASS 213
+ GSG S GS S SS+S S G +GF H S S
Sbjct: 1835 --HGSGSGHSSSYGQHGSGSGWSSSSGRHGSGSGQSSGFG-----------HHESSSWQS 1881
Query: 214 SSSSPGGSRGGSPHHSDCKNGGGVGGGELDKKDQEPKPSPEPAAVSRGGGGEPGAHGGAE 273
S + GS G HS G G+ + +Q S ++ + G G + G +
Sbjct: 1882 SGYTQHGSGSG---HSSSYEQHGSRSGQSSRGEQHGSSSGSSSSYGQHGSGSRQSLGHGQ 1938
Query: 274 SGASGRKSEPPSA---LVGAGHVAPVSPYKPG 302
G+ +S PS G+G + PY G
Sbjct: 1939 HGSGSGQSPSPSRGRHGSGSGQSSSYGPYGSG 1970
Score = 40.4 bits (93), Expect = 0.005
Identities = 72/292 (24%), Positives = 91/292 (31%), Gaps = 29/292 (9%)
Query: 111 NSVAAAANGLGAEKDPGRSAPGAASAAAALKQLGDSPAEDKS-SFKPYSKGSGGGDSRKD 169
+S +A N + G PG S + L D + S S + S G DS +
Sbjct: 130 SSWSAGENDSYSRNVRGSLKPGTESISRRLSFQRDFSGQHNSYSGQSSSYGEQNSDSHQS 189
Query: 170 SGSSSVSSTSSSSSSSPGDKAGFRVPSAACPPFPPHGAPVSASSSSSSPGGSRGGSPHHS 229
SG S S S P + HG+ SSS+ + G G S S
Sbjct: 190 SGRGQCGSGSGQS-----------------PNYGQHGSGSGQSSSNDTHGSGSGQSSGFS 232
Query: 230 DCKNGGGVGGGELDKKDQEPKPSPEPAAVSRGGGGEPGAHGGAESGAS---GRKSEPPSA 286
K+ G G S SR G G + SG+S G+
Sbjct: 233 QHKSSSGQSSGYSQHGSGSGHSSGYGQHGSRSGQSSRGERHRSSSGSSSSYGQHGSGSRQ 292
Query: 287 LVGAGHVAPVSPYKPG---HSVFPLPPSSIGYHGSIVGAYAGYPSQFVPGLDPSKSGLVG 343
+G G S P H SS G HGS G+ Y SG
Sbjct: 293 SLGHGRQGSGSRQSPSHVRHGSGSGHSSSHGQHGS--GSSYSYSRGHYESGSGQTSGF-- 348
Query: 344 GQLSGGLGLPPGKPPSSSPLTGASPPSFLQGLCRDPYCLGGYHGASHLGGSS 395
GQ G G G S +G S G G HG+S SS
Sbjct: 349 GQHESGSGQSSGYSKHGSG-SGHSSSQGQHGSTSGQASSSGQHGSSSRQSSS 399
Score = 38.9 bits (89), Expect = 0.013
Identities = 79/352 (22%), Positives = 108/352 (30%), Gaps = 33/352 (9%)
Query: 107 SSKLNSVAAAANGLGAEKDPGRSAPGAASAAAALKQLGDSPAEDKSSFKPYSKGSG--GG 164
S S + +G G+ G+ S+ + + +S + S F + GSG G
Sbjct: 301 SGSRQSPSHVRHGSGSGHSSSHGQHGSGSSYSYSRGHYESGSGQTSGFGQHESGSGQSSG 360
Query: 165 DSRKDSGSSSVSSTSSSSSSSPGDKAGFRVPSAACPPFPPHGAPVSASSSSSSPG---GS 221
S+ SGS SS S+S G + ++ +G SAS SS G
Sbjct: 361 YSKHGSGSGHSSSQGQHGSTS-GQASSSGQHGSSSRQSSSYGQHESASRHSSGRGQHSSG 419
Query: 222 RGGSPHHSDCKNGGGVGGGELDKKDQEPKPSPEPAAVSRGGGGEPGAHGGAESGASGRKS 281
G SP H +G G Q P R P G S G
Sbjct: 420 SGQSPGHGQRGSGSG----------QSPSSGQHGTGFGRSSSSGPYVSGSGYSSGFGHHE 469
Query: 282 EPPSALVGAGHVAPVSPYKPGHSVFPLPPSSIGYHGSIVGAYAGYPSQFVPGLDPSKSGL 341
G S + GH G HGS G + Q S G
Sbjct: 470 SSSEHSSGYTQHGSGSGHSSGH----------GQHGSRSGQSSRGERQGSSAGSSSSYGQ 519
Query: 342 VGGQLSGGLGLP---PGKPPSSSPLTGASPPSFLQGLCRDPYCLGGYHGAS---HLGGSS 395
G LG G S SP G Q P+ G +S + GS
Sbjct: 520 HGSGSRQSLGHSRHGSGSGQSPSPSRGRHESGSRQSSSYGPHGYGSGRSSSRGPYESGSG 579
Query: 396 CSTCSAHDPAGPSLKAG-GYPLVYPGHPLQPAALSSSAAQAALPGHPLYTYG 446
S+ H + +G G GH S++ Q++ G T G
Sbjct: 580 HSSGLGHQESRSGQSSGYGQHGSSSGHSSTHGQHGSTSGQSSSCGQHGATSG 631
Score = 34.3 bits (77), Expect = 0.33
Identities = 41/190 (21%), Positives = 62/190 (32%), Gaps = 8/190 (4%)
Query: 107 SSKLNSVAAAANGLGAEKDPGRSAPGAASAAAALKQLGDSPAEDKSSFKPYSKGSGG--- 163
S S G G+ + P R G+ ++ S + SS PY G
Sbjct: 2634 SGSRQSSGHGRQGSGSGQSPSRGRHGSGLGHSSSHGQHGSGSGRSSSRGPYESRLGHSSV 2693
Query: 164 -GDSRKDSGSSSVSSTSSSSSSSPGDKAGFRVPSAACPPFPPHGAPVSASSSSSSPGGSR 222
G SG SS S S S + S F G+ S+ SS G R
Sbjct: 2694 FGQHESGSGHSSAYSQHGSGSGHFCSQGQHGSTSGQSSTFDQEGS----STGQSSSYGHR 2749
Query: 223 GGSPHHSDCKNGGGVGGGELDKKDQEPKPSPEPAAVSRGGGGEPGAHGGAESGASGRKSE 282
G S G G G+ + S + ++ + G G + G ++ G+ +
Sbjct: 2750 GSGSSQSSGYGRHGAGSGQSLSHGRHGSGSGQSSSYGQHGSGSGQSSGYSQHGSGSGQDG 2809
Query: 283 PPSALVGAGH 292
G+ H
Sbjct: 2810 YSYCKGGSNH 2819
Score = 32.0 bits (71), Expect = 1.6
Identities = 43/163 (26%), Positives = 58/163 (35%), Gaps = 40/163 (24%)
Query: 118 NGLGAEKDPGRSAPGAASAAAA---LKQLG--------DSPAEDKSSFKPYSKGSGG--- 163
+GLG G+ G+ +++ +LG +S + S++ + GSG
Sbjct: 2660 SGLGHSSSHGQHGSGSGRSSSRGPYESRLGHSSVFGQHESGSGHSSAYSQHGSGSGHFCS 2719
Query: 164 -GDSRKDSGSSSV-----SSTSSSSS-----SSPGDKAGFRVPSAACPPFPPHGAPVSAS 212
G SG SS SST SSS S +G+ A HG S S
Sbjct: 2720 QGQHGSTSGQSSTFDQEGSSTGQSSSYGHRGSGSSQSSGYGRHGAGSGQSLSHGRHGSGS 2779
Query: 213 SSSSSPG---------------GSRGGSPHHSDCKNGGGVGGG 240
SSS G GS G +S CK G GG
Sbjct: 2780 GQSSSYGQHGSGSGQSSGYSQHGSGSGQDGYSYCKGGSNHDGG 2822
>gi|32964830 collagen, type VIII, alpha 2 [Homo sapiens]
Length = 703
Score = 57.0 bits (136), Expect = 5e-08
Identities = 129/519 (24%), Positives = 156/519 (30%), Gaps = 99/519 (19%)
Query: 67 EYLQPLSSTPVSPIELDAK----KSPLALLAQTCSQIGKPDPP----------PSSKLNS 112
+Y+QP+ PV P + K + PL LL G+P PP P
Sbjct: 42 KYIQPMQKGPVGPPFREGKGQYLEMPLPLLPMDLK--GEPGPPGKPGPRGPPGPPGFPGK 99
Query: 113 VAAAANGL----GAEKDPGRSAPGAASAAAALKQLGDSPAEDKSSFKPYSKGSGG----- 163
GL G PG S G A ++G P + +P +G G
Sbjct: 100 PGMGKPGLHGQPGPAGPPGFSRMGKAGPPGLPGKVGP-PGQPGLRGEPGIRGDQGLRGPP 158
Query: 164 GDSRKDSGSSSVSSTSSSSSSSPGDKAGFRVPSAACPPFPPHGAPVSASSSSSSPG---- 219
G S + PG P P PP + + PG
Sbjct: 159 GPPGLPGPSGITIPGKPGAQGVPGPPGFQGEPGPQGEPGPPGDRGLKGDNGVGQPGLPGA 218
Query: 220 GSRGGSPHHSDCKNGGGVG--------GGELDKKDQEPK----PSPEPAAVSRGGGGEPG 267
+GG+P G+G G DK + P P EP AV G G PG
Sbjct: 219 PGQGGAPGPPGLPGPAGLGKPGLDGLPGAPGDKGESGPPGVPGPRGEPGAV--GPKGPPG 276
Query: 268 AHGGAESGASGRKS-EPPSALVGA-GHVAPVSPYKPGHSVFPLPPSSIGYHGSIVGAYAG 325
G GA+G + PS G G P P P P G G AG
Sbjct: 277 VDGVGVPGAAGLPGPQGPSGAKGEPGTRGPPGLIGPTGYGMPGLPGPKGDRGP-----AG 331
Query: 326 YPSQFVPGLDPSKSGLVGGQLSGGLGLPPG-----------KPPSSSPLTGASPPSFLQG 374
P +P + G G Q GLG PPG PP G P + G
Sbjct: 332 VPGLLGDRGEPGEDGEPGEQGPQGLGGPPGLPGSAGLPGRRGPPGPKGEAGPGGPPGVPG 391
Query: 375 LCRD--PYCLGGYHGASHLGGSSCSTCSAHDPAGPSLKAGGYPLV-YPGHPLQPAALSSS 431
+ D P L G G G AH P GP+ G PG P AL
Sbjct: 392 IRGDQGPSGLAGKPGVPGERGLP----GAHGPPGPTGPKGEPGFTGRPGGPGVAGALGQK 447
Query: 432 AAQAALPGHPLYTYGFMLQNEPLPHSCNWVAASGPCDKRFATSEELLSHLRTHTALPGAE 491
LPG P L GP + L L+ LPG
Sbjct: 448 -GDLGLPGQP-----------GLRGPSGIPGLQGPAG---PIGPQGLPGLKGEPGLPGP- 491
Query: 492 KLLAAYPGASGLGSAAAAAAAAASCHLHLPPPAAPGSPG 530
PG G A PP PGSPG
Sbjct: 492 ------PGEGRAGEPGTAGPTG--------PPGVPGSPG 516
>gi|89142737 alpha 3 type IV collagen isoform 5 precursor [Homo
sapiens]
Length = 1424
Score = 56.6 bits (135), Expect = 6e-08
Identities = 91/343 (26%), Positives = 111/343 (32%), Gaps = 54/343 (15%)
Query: 121 GAEKDPG-RSAPGAASAAAALKQLGDS--PAEDKSSFKPYSKGSGGGDSRKDSGSSSVSS 177
G PG + PG A + GD P + S P G G G +
Sbjct: 569 GIPGTPGVKGLPGPKGELALSGEKGDQGPPGDPGSPGSPGPAGPAGPPGYGPQGEPGLQG 628
Query: 178 TSS-SSSSSPGDKAGFR--------VPSAACPPFPP-HGAPVSASSSSSSPGGSRGGSPH 227
T + P +AG R VP PP PP H P S G + G P
Sbjct: 629 TQGVPGAPGPPGEAGPRGELSVSTPVPGPPGPPGPPGHPGPQGPPGIPGSLG--KCGDPG 686
Query: 228 HSDCKNGGGVGG----GELDKKDQEPKPSPEPAAVSRGGGGEPGAHGGAESGASGRKSEP 283
G+ G G K + P + + G GEPG G + G G K EP
Sbjct: 687 LPGPDGEPGIPGIGFPGPPGPKGDQGFPGTKGSLGCPGKMGEPGLPG--KPGLPGAKGEP 744
Query: 284 PSALVGAGHVAPVSPYKPGHSVFPLPPSSIGYHGSIVGAYAGYPSQFVPGLDPSKSGLVG 343
A+ G PG FP + G HG I +PGL GL G
Sbjct: 745 AVAMPGG----------PGTPGFPGERGNSGEHGEIG----------LPGLP----GLPG 780
Query: 344 GQLSGGLGLPPGKPPSSSPLTGASPPSFLQGLCRDPYCLGGYHGASHLGGSSCSTCSAHD 403
+ GL P G P P PP R L G +G G T D
Sbjct: 781 TPGNEGLDGPRGDPGQPGPPGEQGPPGRCIEGPRGAQGLPGLNGLKGQQGRRGKTGPKGD 840
Query: 404 PAGPSLKAGGYP-----LVYPGHPLQPAALSSSAAQAALPGHP 441
P P L G+P PGH + L Q PG+P
Sbjct: 841 PGIPGLDRSGFPGETGSPGIPGHQGEMGPL----GQRGYPGNP 879
Score = 38.9 bits (89), Expect = 0.013
Identities = 75/291 (25%), Positives = 90/291 (30%), Gaps = 43/291 (14%)
Query: 82 LDAKKSPLALLAQTCSQIGKPDPP--PSSKLNSVAAAANGLGAEKDPG----RSAPGAAS 135
L K LAL + Q G P P P S + A G G + +PG + PGA
Sbjct: 579 LPGPKGELALSGEKGDQ-GPPGDPGSPGSPGPAGPAGPPGYGPQGEPGLQGTQGVPGAPG 637
Query: 136 AAAALKQLGDSPAEDKSSFKPYSKGSGGGDSRKDSGSSSVSSTSSSSSSSPGDKAGFRVP 195
G+ P G G + S PG +P
Sbjct: 638 PPGEAGPRGELSVSTPVPGPPGPPGPPGHPGPQGPPGIPGSLGKCGDPGLPGPDGEPGIP 697
Query: 196 SAACPPFPPHGAPVSASSSSSSPGGSRGGSPHHSDCKNGGGVGGGELDKKDQEPKPSPEP 255
P P P G +G G +G L K P EP
Sbjct: 698 GIGFPGPP-------------GPKGDQGFPGTKGSLGCPGKMGEPGLPGKPGLPGAKGEP 744
Query: 256 AAVSRGGGGEPGAHGGAESGASGRKSEPPSALVGAGHVAPVSPYKPGHSVF--------- 306
A GG G PG G E G SG E L G P P PG+
Sbjct: 745 AVAMPGGPGTPGFPG--ERGNSGEHGE--IGLPG----LPGLPGTPGNEGLDGPRGDPGQ 796
Query: 307 PLPPSSIGYHGSIVGAYAGYPSQFVPGLDPSKSGLVGGQLSGGLGLPPGKP 357
P PP G G + G +Q +PGL +GL G Q G P G P
Sbjct: 797 PGPPGEQGPPGRCIEGPRG--AQGLPGL----NGLKGQQGRRGKTGPKGDP 841
Score = 37.4 bits (85), Expect = 0.039
Identities = 98/384 (25%), Positives = 123/384 (32%), Gaps = 90/384 (23%)
Query: 209 VSASSSSSSPGGSRGGSPHHSDCKNGG--GVGGGELDKKDQEPK-PSPEPAAVSRGGGGE 265
+ P G RG + ++ + G G G + + P+ PS P G
Sbjct: 328 IKGQKGDIGPPGFRGPTEYYDTYQEKGDEGTPGPPGPRGARGPQGPSGPPGVPGSPGSSR 387
Query: 266 PGAHGGAE----SGASGRKSEPPSALVGA--GHVAPVSPYKPGHSVFPLPPSSI------ 313
PG G G+ G + P +G SP PG P PP I
Sbjct: 388 PGLRGAPGWPGLKGSKGERGRPGKDAMGTPGSPGCAGSPGLPGSPGPPGPPGDIVFRKGP 447
Query: 314 -GYHGSIVGAYAGYPSQFVPGLDPSKSGLVGGQLSGGLGLPPGKPPSSSPLTGASPPSFL 372
G HG + Y G P +PG+D K G L PG PP L G L
Sbjct: 448 PGDHG--LPGYLGSPG--IPGVDGPKGE--PGLLCTQCPYIPG-PPGLPGLPG------L 494
Query: 373 QGLCRDPYCLGGYHGASHLGGSSCSTCSAHDPAGPSLK-AGGYPLVY--PGHPLQPAALS 429
G+ P G GA+ L GS S + P P A G P + G LQP
Sbjct: 495 HGVKGIP----GRQGAAGLKGSPGSPGNTGLPGFPGFPGAQGDPGLKGEKGETLQPEG-- 548
Query: 430 SSAAQAALPGHPLYTYGFMLQNEPLPHSCNWVAASGPCDKRFATSEELLSHLRTHTALPG 489
Q +PG P L+ +P + +PG
Sbjct: 549 ----QVGVPGDP------GLRGQPGRKGLD--------------------------GIPG 572
Query: 490 AEKLLAAYPGASGLGSAAAAAAAAASCHLHLPPPAAPGSPGSLSLRNPHTLGLSRYHPYG 549
PG GL A + PP PGSPGS P G Y P G
Sbjct: 573 T-------PGVKGLPGPKGELALSGEKG-DQGPPGDPGSPGSPGPAGP--AGPPGYGPQG 622
Query: 550 KSHLSTAGGLAVPSLP----TAGP 569
+ L G VP P AGP
Sbjct: 623 EPGLQ--GTQGVPGAPGPPGEAGP 644
Score = 32.3 bits (72), Expect = 1.3
Identities = 73/309 (23%), Positives = 90/309 (29%), Gaps = 30/309 (9%)
Query: 100 GKPDPPPSSKLNSVAAAANGLGAEKDPGRSAPGAASAAAALKQLGDSPAEDKSSFKPYSK 159
G P P S + G +PG LK L P
Sbjct: 940 GNPGPSEISHVIGDKGEPGLKGFAGNPGEKGNRGVPGMPGLKGLKGLPGPAGPPGPRGDL 999
Query: 160 GSGGGDSRKDSGSSSVSSTSSSSSSSPGDKAGFRVPSAACPPFPP--HGAPVSASSSSSS 217
GS G S + S G + P A P P HG
Sbjct: 1000 GSTGNPGEPGLRGIPGSMGNMGMPGSKGKRGTLGFPGRAGRPGLPGIHGL----QGDKGE 1055
Query: 218 PGGSRGGSPHHSDCKNGGGVGGGELDKKDQEPKPSPEPAAVSRGGGGEPGAHGGAESGAS 277
PG S G P G+ G ++ KK + +P P G G PG+ G G
Sbjct: 1056 PGYSEGTRPGPPGPTGDPGLPG-DMGKKGEMGQPGPPGHLGPAGPEGAPGSPG--SPGLP 1112
Query: 278 GRKSEPPSALVGAGHVAPVSP----YKPGHSVFPLPPSSIGYHG-----SIVGAYAGYPS 328
G K P L G + P PG FP P +G G I G
Sbjct: 1113 G-KPGPHGDLGFKGIKGLLGPPGIRGPPGLPGFPGSPGPMGIRGDQGRDGIPGPAGEKGE 1171
Query: 329 QFVPGLDPSKSGLVGGQ-LSGGLGLP--PGKPPSSSPLTGASPPSFLQGLCRDPYCLGGY 385
+ P G G Q G G P PG P + A P R P + G+
Sbjct: 1172 TGLLRAPPGPRGNPGAQGAKGDRGAPGFPGLPGRKGAMGDAGP--------RGPTGIEGF 1223
Query: 386 HGASHLGGS 394
G L G+
Sbjct: 1224 PGPPGLPGA 1232
>gi|89142735 alpha 3 type IV collagen isoform 4 precursor [Homo
sapiens]
Length = 1494
Score = 56.6 bits (135), Expect = 6e-08
Identities = 91/343 (26%), Positives = 111/343 (32%), Gaps = 54/343 (15%)
Query: 121 GAEKDPG-RSAPGAASAAAALKQLGDS--PAEDKSSFKPYSKGSGGGDSRKDSGSSSVSS 177
G PG + PG A + GD P + S P G G G +
Sbjct: 569 GIPGTPGVKGLPGPKGELALSGEKGDQGPPGDPGSPGSPGPAGPAGPPGYGPQGEPGLQG 628
Query: 178 TSS-SSSSSPGDKAGFR--------VPSAACPPFPP-HGAPVSASSSSSSPGGSRGGSPH 227
T + P +AG R VP PP PP H P S G + G P
Sbjct: 629 TQGVPGAPGPPGEAGPRGELSVSTPVPGPPGPPGPPGHPGPQGPPGIPGSLG--KCGDPG 686
Query: 228 HSDCKNGGGVGG----GELDKKDQEPKPSPEPAAVSRGGGGEPGAHGGAESGASGRKSEP 283
G+ G G K + P + + G GEPG G + G G K EP
Sbjct: 687 LPGPDGEPGIPGIGFPGPPGPKGDQGFPGTKGSLGCPGKMGEPGLPG--KPGLPGAKGEP 744
Query: 284 PSALVGAGHVAPVSPYKPGHSVFPLPPSSIGYHGSIVGAYAGYPSQFVPGLDPSKSGLVG 343
A+ G PG FP + G HG I +PGL GL G
Sbjct: 745 AVAMPGG----------PGTPGFPGERGNSGEHGEIG----------LPGLP----GLPG 780
Query: 344 GQLSGGLGLPPGKPPSSSPLTGASPPSFLQGLCRDPYCLGGYHGASHLGGSSCSTCSAHD 403
+ GL P G P P PP R L G +G G T D
Sbjct: 781 TPGNEGLDGPRGDPGQPGPPGEQGPPGRCIEGPRGAQGLPGLNGLKGQQGRRGKTGPKGD 840
Query: 404 PAGPSLKAGGYP-----LVYPGHPLQPAALSSSAAQAALPGHP 441
P P L G+P PGH + L Q PG+P
Sbjct: 841 PGIPGLDRSGFPGETGSPGIPGHQGEMGPL----GQRGYPGNP 879
Score = 38.9 bits (89), Expect = 0.013
Identities = 75/291 (25%), Positives = 90/291 (30%), Gaps = 43/291 (14%)
Query: 82 LDAKKSPLALLAQTCSQIGKPDPP--PSSKLNSVAAAANGLGAEKDPG----RSAPGAAS 135
L K LAL + Q G P P P S + A G G + +PG + PGA
Sbjct: 579 LPGPKGELALSGEKGDQ-GPPGDPGSPGSPGPAGPAGPPGYGPQGEPGLQGTQGVPGAPG 637
Query: 136 AAAALKQLGDSPAEDKSSFKPYSKGSGGGDSRKDSGSSSVSSTSSSSSSSPGDKAGFRVP 195
G+ P G G + S PG +P
Sbjct: 638 PPGEAGPRGELSVSTPVPGPPGPPGPPGHPGPQGPPGIPGSLGKCGDPGLPGPDGEPGIP 697
Query: 196 SAACPPFPPHGAPVSASSSSSSPGGSRGGSPHHSDCKNGGGVGGGELDKKDQEPKPSPEP 255
P P P G +G G +G L K P EP
Sbjct: 698 GIGFPGPP-------------GPKGDQGFPGTKGSLGCPGKMGEPGLPGKPGLPGAKGEP 744
Query: 256 AAVSRGGGGEPGAHGGAESGASGRKSEPPSALVGAGHVAPVSPYKPGHSVF--------- 306
A GG G PG G E G SG E L G P P PG+
Sbjct: 745 AVAMPGGPGTPGFPG--ERGNSGEHGE--IGLPG----LPGLPGTPGNEGLDGPRGDPGQ 796
Query: 307 PLPPSSIGYHGSIVGAYAGYPSQFVPGLDPSKSGLVGGQLSGGLGLPPGKP 357
P PP G G + G +Q +PGL +GL G Q G P G P
Sbjct: 797 PGPPGEQGPPGRCIEGPRG--AQGLPGL----NGLKGQQGRRGKTGPKGDP 841
Score = 37.4 bits (85), Expect = 0.039
Identities = 98/384 (25%), Positives = 123/384 (32%), Gaps = 90/384 (23%)
Query: 209 VSASSSSSSPGGSRGGSPHHSDCKNGG--GVGGGELDKKDQEPK-PSPEPAAVSRGGGGE 265
+ P G RG + ++ + G G G + + P+ PS P G
Sbjct: 328 IKGQKGDIGPPGFRGPTEYYDTYQEKGDEGTPGPPGPRGARGPQGPSGPPGVPGSPGSSR 387
Query: 266 PGAHGGAE----SGASGRKSEPPSALVGA--GHVAPVSPYKPGHSVFPLPPSSI------ 313
PG G G+ G + P +G SP PG P PP I
Sbjct: 388 PGLRGAPGWPGLKGSKGERGRPGKDAMGTPGSPGCAGSPGLPGSPGPPGPPGDIVFRKGP 447
Query: 314 -GYHGSIVGAYAGYPSQFVPGLDPSKSGLVGGQLSGGLGLPPGKPPSSSPLTGASPPSFL 372
G HG + Y G P +PG+D K G L PG PP L G L
Sbjct: 448 PGDHG--LPGYLGSPG--IPGVDGPKGE--PGLLCTQCPYIPG-PPGLPGLPG------L 494
Query: 373 QGLCRDPYCLGGYHGASHLGGSSCSTCSAHDPAGPSLK-AGGYPLVY--PGHPLQPAALS 429
G+ P G GA+ L GS S + P P A G P + G LQP
Sbjct: 495 HGVKGIP----GRQGAAGLKGSPGSPGNTGLPGFPGFPGAQGDPGLKGEKGETLQPEG-- 548
Query: 430 SSAAQAALPGHPLYTYGFMLQNEPLPHSCNWVAASGPCDKRFATSEELLSHLRTHTALPG 489
Q +PG P L+ +P + +PG
Sbjct: 549 ----QVGVPGDP------GLRGQPGRKGLD--------------------------GIPG 572
Query: 490 AEKLLAAYPGASGLGSAAAAAAAAASCHLHLPPPAAPGSPGSLSLRNPHTLGLSRYHPYG 549
PG GL A + PP PGSPGS P G Y P G
Sbjct: 573 T-------PGVKGLPGPKGELALSGEKG-DQGPPGDPGSPGSPGPAGP--AGPPGYGPQG 622
Query: 550 KSHLSTAGGLAVPSLP----TAGP 569
+ L G VP P AGP
Sbjct: 623 EPGLQ--GTQGVPGAPGPPGEAGP 644
Score = 32.3 bits (72), Expect = 1.3
Identities = 73/309 (23%), Positives = 90/309 (29%), Gaps = 30/309 (9%)
Query: 100 GKPDPPPSSKLNSVAAAANGLGAEKDPGRSAPGAASAAAALKQLGDSPAEDKSSFKPYSK 159
G P P S + G +PG LK L P
Sbjct: 940 GNPGPSEISHVIGDKGEPGLKGFAGNPGEKGNRGVPGMPGLKGLKGLPGPAGPPGPRGDL 999
Query: 160 GSGGGDSRKDSGSSSVSSTSSSSSSSPGDKAGFRVPSAACPPFPP--HGAPVSASSSSSS 217
GS G S + S G + P A P P HG
Sbjct: 1000 GSTGNPGEPGLRGIPGSMGNMGMPGSKGKRGTLGFPGRAGRPGLPGIHGL----QGDKGE 1055
Query: 218 PGGSRGGSPHHSDCKNGGGVGGGELDKKDQEPKPSPEPAAVSRGGGGEPGAHGGAESGAS 277
PG S G P G+ G ++ KK + +P P G G PG+ G G
Sbjct: 1056 PGYSEGTRPGPPGPTGDPGLPG-DMGKKGEMGQPGPPGHLGPAGPEGAPGSPG--SPGLP 1112
Query: 278 GRKSEPPSALVGAGHVAPVSP----YKPGHSVFPLPPSSIGYHG-----SIVGAYAGYPS 328
G K P L G + P PG FP P +G G I G
Sbjct: 1113 G-KPGPHGDLGFKGIKGLLGPPGIRGPPGLPGFPGSPGPMGIRGDQGRDGIPGPAGEKGE 1171
Query: 329 QFVPGLDPSKSGLVGGQ-LSGGLGLP--PGKPPSSSPLTGASPPSFLQGLCRDPYCLGGY 385
+ P G G Q G G P PG P + A P R P + G+
Sbjct: 1172 TGLLRAPPGPRGNPGAQGAKGDRGAPGFPGLPGRKGAMGDAGP--------RGPTGIEGF 1223
Query: 386 HGASHLGGS 394
G L G+
Sbjct: 1224 PGPPGLPGA 1232
>gi|89142733 alpha 3 type IV collagen isoform 2 precursor [Homo
sapiens]
Length = 1637
Score = 56.6 bits (135), Expect = 6e-08
Identities = 91/343 (26%), Positives = 111/343 (32%), Gaps = 54/343 (15%)
Query: 121 GAEKDPG-RSAPGAASAAAALKQLGDS--PAEDKSSFKPYSKGSGGGDSRKDSGSSSVSS 177
G PG + PG A + GD P + S P G G G +
Sbjct: 569 GIPGTPGVKGLPGPKGELALSGEKGDQGPPGDPGSPGSPGPAGPAGPPGYGPQGEPGLQG 628
Query: 178 TSS-SSSSSPGDKAGFR--------VPSAACPPFPP-HGAPVSASSSSSSPGGSRGGSPH 227
T + P +AG R VP PP PP H P S G + G P
Sbjct: 629 TQGVPGAPGPPGEAGPRGELSVSTPVPGPPGPPGPPGHPGPQGPPGIPGSLG--KCGDPG 686
Query: 228 HSDCKNGGGVGG----GELDKKDQEPKPSPEPAAVSRGGGGEPGAHGGAESGASGRKSEP 283
G+ G G K + P + + G GEPG G + G G K EP
Sbjct: 687 LPGPDGEPGIPGIGFPGPPGPKGDQGFPGTKGSLGCPGKMGEPGLPG--KPGLPGAKGEP 744
Query: 284 PSALVGAGHVAPVSPYKPGHSVFPLPPSSIGYHGSIVGAYAGYPSQFVPGLDPSKSGLVG 343
A+ G PG FP + G HG I +PGL GL G
Sbjct: 745 AVAMPGG----------PGTPGFPGERGNSGEHGEIG----------LPGLP----GLPG 780
Query: 344 GQLSGGLGLPPGKPPSSSPLTGASPPSFLQGLCRDPYCLGGYHGASHLGGSSCSTCSAHD 403
+ GL P G P P PP R L G +G G T D
Sbjct: 781 TPGNEGLDGPRGDPGQPGPPGEQGPPGRCIEGPRGAQGLPGLNGLKGQQGRRGKTGPKGD 840
Query: 404 PAGPSLKAGGYP-----LVYPGHPLQPAALSSSAAQAALPGHP 441
P P L G+P PGH + L Q PG+P
Sbjct: 841 PGIPGLDRSGFPGETGSPGIPGHQGEMGPL----GQRGYPGNP 879
Score = 38.9 bits (89), Expect = 0.013
Identities = 75/291 (25%), Positives = 90/291 (30%), Gaps = 43/291 (14%)
Query: 82 LDAKKSPLALLAQTCSQIGKPDPP--PSSKLNSVAAAANGLGAEKDPG----RSAPGAAS 135
L K LAL + Q G P P P S + A G G + +PG + PGA
Sbjct: 579 LPGPKGELALSGEKGDQ-GPPGDPGSPGSPGPAGPAGPPGYGPQGEPGLQGTQGVPGAPG 637
Query: 136 AAAALKQLGDSPAEDKSSFKPYSKGSGGGDSRKDSGSSSVSSTSSSSSSSPGDKAGFRVP 195
G+ P G G + S PG +P
Sbjct: 638 PPGEAGPRGELSVSTPVPGPPGPPGPPGHPGPQGPPGIPGSLGKCGDPGLPGPDGEPGIP 697
Query: 196 SAACPPFPPHGAPVSASSSSSSPGGSRGGSPHHSDCKNGGGVGGGELDKKDQEPKPSPEP 255
P P P G +G G +G L K P EP
Sbjct: 698 GIGFPGPP-------------GPKGDQGFPGTKGSLGCPGKMGEPGLPGKPGLPGAKGEP 744
Query: 256 AAVSRGGGGEPGAHGGAESGASGRKSEPPSALVGAGHVAPVSPYKPGHSVF--------- 306
A GG G PG G E G SG E L G P P PG+
Sbjct: 745 AVAMPGGPGTPGFPG--ERGNSGEHGE--IGLPG----LPGLPGTPGNEGLDGPRGDPGQ 796
Query: 307 PLPPSSIGYHGSIVGAYAGYPSQFVPGLDPSKSGLVGGQLSGGLGLPPGKP 357
P PP G G + G +Q +PGL +GL G Q G P G P
Sbjct: 797 PGPPGEQGPPGRCIEGPRG--AQGLPGL----NGLKGQQGRRGKTGPKGDP 841
Score = 37.4 bits (85), Expect = 0.039
Identities = 98/384 (25%), Positives = 123/384 (32%), Gaps = 90/384 (23%)
Query: 209 VSASSSSSSPGGSRGGSPHHSDCKNGG--GVGGGELDKKDQEPK-PSPEPAAVSRGGGGE 265
+ P G RG + ++ + G G G + + P+ PS P G
Sbjct: 328 IKGQKGDIGPPGFRGPTEYYDTYQEKGDEGTPGPPGPRGARGPQGPSGPPGVPGSPGSSR 387
Query: 266 PGAHGGAE----SGASGRKSEPPSALVGA--GHVAPVSPYKPGHSVFPLPPSSI------ 313
PG G G+ G + P +G SP PG P PP I
Sbjct: 388 PGLRGAPGWPGLKGSKGERGRPGKDAMGTPGSPGCAGSPGLPGSPGPPGPPGDIVFRKGP 447
Query: 314 -GYHGSIVGAYAGYPSQFVPGLDPSKSGLVGGQLSGGLGLPPGKPPSSSPLTGASPPSFL 372
G HG + Y G P +PG+D K G L PG PP L G L
Sbjct: 448 PGDHG--LPGYLGSPG--IPGVDGPKGE--PGLLCTQCPYIPG-PPGLPGLPG------L 494
Query: 373 QGLCRDPYCLGGYHGASHLGGSSCSTCSAHDPAGPSLK-AGGYPLVY--PGHPLQPAALS 429
G+ P G GA+ L GS S + P P A G P + G LQP
Sbjct: 495 HGVKGIP----GRQGAAGLKGSPGSPGNTGLPGFPGFPGAQGDPGLKGEKGETLQPEG-- 548
Query: 430 SSAAQAALPGHPLYTYGFMLQNEPLPHSCNWVAASGPCDKRFATSEELLSHLRTHTALPG 489
Q +PG P L+ +P + +PG
Sbjct: 549 ----QVGVPGDP------GLRGQPGRKGLD--------------------------GIPG 572
Query: 490 AEKLLAAYPGASGLGSAAAAAAAAASCHLHLPPPAAPGSPGSLSLRNPHTLGLSRYHPYG 549
PG GL A + PP PGSPGS P G Y P G
Sbjct: 573 T-------PGVKGLPGPKGELALSGEKG-DQGPPGDPGSPGSPGPAGP--AGPPGYGPQG 622
Query: 550 KSHLSTAGGLAVPSLP----TAGP 569
+ L G VP P AGP
Sbjct: 623 EPGLQ--GTQGVPGAPGPPGEAGP 644
Score = 32.3 bits (72), Expect = 1.3
Identities = 73/309 (23%), Positives = 90/309 (29%), Gaps = 30/309 (9%)
Query: 100 GKPDPPPSSKLNSVAAAANGLGAEKDPGRSAPGAASAAAALKQLGDSPAEDKSSFKPYSK 159
G P P S + G +PG LK L P
Sbjct: 940 GNPGPSEISHVIGDKGEPGLKGFAGNPGEKGNRGVPGMPGLKGLKGLPGPAGPPGPRGDL 999
Query: 160 GSGGGDSRKDSGSSSVSSTSSSSSSSPGDKAGFRVPSAACPPFPP--HGAPVSASSSSSS 217
GS G S + S G + P A P P HG
Sbjct: 1000 GSTGNPGEPGLRGIPGSMGNMGMPGSKGKRGTLGFPGRAGRPGLPGIHGL----QGDKGE 1055
Query: 218 PGGSRGGSPHHSDCKNGGGVGGGELDKKDQEPKPSPEPAAVSRGGGGEPGAHGGAESGAS 277
PG S G P G+ G ++ KK + +P P G G PG+ G G
Sbjct: 1056 PGYSEGTRPGPPGPTGDPGLPG-DMGKKGEMGQPGPPGHLGPAGPEGAPGSPG--SPGLP 1112
Query: 278 GRKSEPPSALVGAGHVAPVSP----YKPGHSVFPLPPSSIGYHG-----SIVGAYAGYPS 328
G K P L G + P PG FP P +G G I G
Sbjct: 1113 G-KPGPHGDLGFKGIKGLLGPPGIRGPPGLPGFPGSPGPMGIRGDQGRDGIPGPAGEKGE 1171
Query: 329 QFVPGLDPSKSGLVGGQ-LSGGLGLP--PGKPPSSSPLTGASPPSFLQGLCRDPYCLGGY 385
+ P G G Q G G P PG P + A P R P + G+
Sbjct: 1172 TGLLRAPPGPRGNPGAQGAKGDRGAPGFPGLPGRKGAMGDAGP--------RGPTGIEGF 1223
Query: 386 HGASHLGGS 394
G L G+
Sbjct: 1224 PGPPGLPGA 1232
>gi|89142730 alpha 3 type IV collagen isoform 1 precursor [Homo
sapiens]
Length = 1670
Score = 56.6 bits (135), Expect = 6e-08
Identities = 91/343 (26%), Positives = 111/343 (32%), Gaps = 54/343 (15%)
Query: 121 GAEKDPG-RSAPGAASAAAALKQLGDS--PAEDKSSFKPYSKGSGGGDSRKDSGSSSVSS 177
G PG + PG A + GD P + S P G G G +
Sbjct: 569 GIPGTPGVKGLPGPKGELALSGEKGDQGPPGDPGSPGSPGPAGPAGPPGYGPQGEPGLQG 628
Query: 178 TSS-SSSSSPGDKAGFR--------VPSAACPPFPP-HGAPVSASSSSSSPGGSRGGSPH 227
T + P +AG R VP PP PP H P S G + G P
Sbjct: 629 TQGVPGAPGPPGEAGPRGELSVSTPVPGPPGPPGPPGHPGPQGPPGIPGSLG--KCGDPG 686
Query: 228 HSDCKNGGGVGG----GELDKKDQEPKPSPEPAAVSRGGGGEPGAHGGAESGASGRKSEP 283
G+ G G K + P + + G GEPG G + G G K EP
Sbjct: 687 LPGPDGEPGIPGIGFPGPPGPKGDQGFPGTKGSLGCPGKMGEPGLPG--KPGLPGAKGEP 744
Query: 284 PSALVGAGHVAPVSPYKPGHSVFPLPPSSIGYHGSIVGAYAGYPSQFVPGLDPSKSGLVG 343
A+ G PG FP + G HG I +PGL GL G
Sbjct: 745 AVAMPGG----------PGTPGFPGERGNSGEHGEIG----------LPGLP----GLPG 780
Query: 344 GQLSGGLGLPPGKPPSSSPLTGASPPSFLQGLCRDPYCLGGYHGASHLGGSSCSTCSAHD 403
+ GL P G P P PP R L G +G G T D
Sbjct: 781 TPGNEGLDGPRGDPGQPGPPGEQGPPGRCIEGPRGAQGLPGLNGLKGQQGRRGKTGPKGD 840
Query: 404 PAGPSLKAGGYP-----LVYPGHPLQPAALSSSAAQAALPGHP 441
P P L G+P PGH + L Q PG+P
Sbjct: 841 PGIPGLDRSGFPGETGSPGIPGHQGEMGPL----GQRGYPGNP 879
Score = 38.9 bits (89), Expect = 0.013
Identities = 75/291 (25%), Positives = 90/291 (30%), Gaps = 43/291 (14%)
Query: 82 LDAKKSPLALLAQTCSQIGKPDPP--PSSKLNSVAAAANGLGAEKDPG----RSAPGAAS 135
L K LAL + Q G P P P S + A G G + +PG + PGA
Sbjct: 579 LPGPKGELALSGEKGDQ-GPPGDPGSPGSPGPAGPAGPPGYGPQGEPGLQGTQGVPGAPG 637
Query: 136 AAAALKQLGDSPAEDKSSFKPYSKGSGGGDSRKDSGSSSVSSTSSSSSSSPGDKAGFRVP 195
G+ P G G + S PG +P
Sbjct: 638 PPGEAGPRGELSVSTPVPGPPGPPGPPGHPGPQGPPGIPGSLGKCGDPGLPGPDGEPGIP 697
Query: 196 SAACPPFPPHGAPVSASSSSSSPGGSRGGSPHHSDCKNGGGVGGGELDKKDQEPKPSPEP 255
P P P G +G G +G L K P EP
Sbjct: 698 GIGFPGPP-------------GPKGDQGFPGTKGSLGCPGKMGEPGLPGKPGLPGAKGEP 744
Query: 256 AAVSRGGGGEPGAHGGAESGASGRKSEPPSALVGAGHVAPVSPYKPGHSVF--------- 306
A GG G PG G E G SG E L G P P PG+
Sbjct: 745 AVAMPGGPGTPGFPG--ERGNSGEHGE--IGLPG----LPGLPGTPGNEGLDGPRGDPGQ 796
Query: 307 PLPPSSIGYHGSIVGAYAGYPSQFVPGLDPSKSGLVGGQLSGGLGLPPGKP 357
P PP G G + G +Q +PGL +GL G Q G P G P
Sbjct: 797 PGPPGEQGPPGRCIEGPRG--AQGLPGL----NGLKGQQGRRGKTGPKGDP 841
Score = 37.4 bits (85), Expect = 0.039
Identities = 98/384 (25%), Positives = 123/384 (32%), Gaps = 90/384 (23%)
Query: 209 VSASSSSSSPGGSRGGSPHHSDCKNGG--GVGGGELDKKDQEPK-PSPEPAAVSRGGGGE 265
+ P G RG + ++ + G G G + + P+ PS P G
Sbjct: 328 IKGQKGDIGPPGFRGPTEYYDTYQEKGDEGTPGPPGPRGARGPQGPSGPPGVPGSPGSSR 387
Query: 266 PGAHGGAE----SGASGRKSEPPSALVGA--GHVAPVSPYKPGHSVFPLPPSSI------ 313
PG G G+ G + P +G SP PG P PP I
Sbjct: 388 PGLRGAPGWPGLKGSKGERGRPGKDAMGTPGSPGCAGSPGLPGSPGPPGPPGDIVFRKGP 447
Query: 314 -GYHGSIVGAYAGYPSQFVPGLDPSKSGLVGGQLSGGLGLPPGKPPSSSPLTGASPPSFL 372
G HG + Y G P +PG+D K G L PG PP L G L
Sbjct: 448 PGDHG--LPGYLGSPG--IPGVDGPKGE--PGLLCTQCPYIPG-PPGLPGLPG------L 494
Query: 373 QGLCRDPYCLGGYHGASHLGGSSCSTCSAHDPAGPSLK-AGGYPLVY--PGHPLQPAALS 429
G+ P G GA+ L GS S + P P A G P + G LQP
Sbjct: 495 HGVKGIP----GRQGAAGLKGSPGSPGNTGLPGFPGFPGAQGDPGLKGEKGETLQPEG-- 548
Query: 430 SSAAQAALPGHPLYTYGFMLQNEPLPHSCNWVAASGPCDKRFATSEELLSHLRTHTALPG 489
Q +PG P L+ +P + +PG
Sbjct: 549 ----QVGVPGDP------GLRGQPGRKGLD--------------------------GIPG 572
Query: 490 AEKLLAAYPGASGLGSAAAAAAAAASCHLHLPPPAAPGSPGSLSLRNPHTLGLSRYHPYG 549
PG GL A + PP PGSPGS P G Y P G
Sbjct: 573 T-------PGVKGLPGPKGELALSGEKG-DQGPPGDPGSPGSPGPAGP--AGPPGYGPQG 622
Query: 550 KSHLSTAGGLAVPSLP----TAGP 569
+ L G VP P AGP
Sbjct: 623 EPGLQ--GTQGVPGAPGPPGEAGP 644
Score = 32.3 bits (72), Expect = 1.3
Identities = 73/309 (23%), Positives = 90/309 (29%), Gaps = 30/309 (9%)
Query: 100 GKPDPPPSSKLNSVAAAANGLGAEKDPGRSAPGAASAAAALKQLGDSPAEDKSSFKPYSK 159
G P P S + G +PG LK L P
Sbjct: 940 GNPGPSEISHVIGDKGEPGLKGFAGNPGEKGNRGVPGMPGLKGLKGLPGPAGPPGPRGDL 999
Query: 160 GSGGGDSRKDSGSSSVSSTSSSSSSSPGDKAGFRVPSAACPPFPP--HGAPVSASSSSSS 217
GS G S + S G + P A P P HG
Sbjct: 1000 GSTGNPGEPGLRGIPGSMGNMGMPGSKGKRGTLGFPGRAGRPGLPGIHGL----QGDKGE 1055
Query: 218 PGGSRGGSPHHSDCKNGGGVGGGELDKKDQEPKPSPEPAAVSRGGGGEPGAHGGAESGAS 277
PG S G P G+ G ++ KK + +P P G G PG+ G G
Sbjct: 1056 PGYSEGTRPGPPGPTGDPGLPG-DMGKKGEMGQPGPPGHLGPAGPEGAPGSPG--SPGLP 1112
Query: 278 GRKSEPPSALVGAGHVAPVSP----YKPGHSVFPLPPSSIGYHG-----SIVGAYAGYPS 328
G K P L G + P PG FP P +G G I G
Sbjct: 1113 G-KPGPHGDLGFKGIKGLLGPPGIRGPPGLPGFPGSPGPMGIRGDQGRDGIPGPAGEKGE 1171
Query: 329 QFVPGLDPSKSGLVGGQ-LSGGLGLP--PGKPPSSSPLTGASPPSFLQGLCRDPYCLGGY 385
+ P G G Q G G P PG P + A P R P + G+
Sbjct: 1172 TGLLRAPPGPRGNPGAQGAKGDRGAPGFPGLPGRKGAMGDAGP--------RGPTGIEGF 1223
Query: 386 HGASHLGGS 394
G L G+
Sbjct: 1224 PGPPGLPGA 1232
>gi|110349772 alpha 1 type I collagen preproprotein [Homo sapiens]
Length = 1464
Score = 55.8 bits (133), Expect = 1e-07
Identities = 78/271 (28%), Positives = 101/271 (37%), Gaps = 40/271 (14%)
Query: 100 GKPDPPPSSKLNSVAAAANGLGAEKDPGRSAPGAASAAAALKQLGDSPAEDKSSFKPYSK 159
G PP + A GA+ D G APGA + A L P E ++ P K
Sbjct: 686 GVQGPPGPAGPRGANGAPGNDGAKGDAG--APGAPGSQGA-PGLQGMPGERGAAGLPGPK 742
Query: 160 GSGGGDSRKDSGSSSVSSTSSSSSSSPGDKAGFRVPSAACPPFPPHGAPVSASSSSSSPG 219
G G D+G + SPG K G R + P P GAP S P
Sbjct: 743 GDRG-----DAGPKG-------ADGSPG-KDGVRGLTGPIGPPGPAGAP--GDKGESGPS 787
Query: 220 GSRGGSPHHSDCKNGGGVGGGELDKKDQEPKPSPEPAAVSRGGGGEPGAHGGAESGASGR 279
G G + G G D+ + P P P A G G+PGA G E G +G
Sbjct: 788 GPAGPT----------GARGAPGDRGEPGP-PGPAGFAGPPGADGQPGAKG--EPGDAGA 834
Query: 280 KSE--PPSALVGAGHVAPV----SPYKPGHSVFPLPPSSIGYHGSI--VGAYAGYPSQFV 331
K + PP AG P+ +P G PP + G+ G+ VG +
Sbjct: 835 KGDAGPPGPAGPAGPPGPIGNVGAPGAKGARGSAGPPGATGFPGAAGRVGPPGPSGNAGP 894
Query: 332 PGLDPSKSGLVGGQLSGGLGLPPGKPPSSSP 362
PG P +G GG+ G P G+P P
Sbjct: 895 PG-PPGPAGKEGGKGPRGETGPAGRPGEVGP 924
Score = 53.5 bits (127), Expect = 5e-07
Identities = 110/408 (26%), Positives = 137/408 (33%), Gaps = 66/408 (16%)
Query: 156 PYSKGSGGGDSRKDSGSSSVSSTSSSSSSSPGDKAGFR-VPSAACPPFP-----PHGAPV 209
P G GG + + S ST S P +G R +P P P P G P
Sbjct: 150 PGPPGLGGNFAPQLSYGYDEKSTGGISVPGPMGPSGPRGLPGPPGAPGPQGFQGPPGEP- 208
Query: 210 SASSSSSSPGGSRGGSPHHSDCKNGGGVGGGELDKKDQEPKPSPEPAAVSRGGGGEPGAH 269
+S P G RG P KNG G+ + + P P+ A G G PG
Sbjct: 209 -GEPGASGPMGPRG--PPGPPGKNGDDGEAGKPGRPGERGPPGPQGARGLPGTAGLPGMK 265
Query: 270 G--------GA--ESGASGRKSEP--PSALVGAGHVAPVS-PYKPGHSVFPLPPSSIGYH 316
G GA ++G +G K EP P G + P P + G P P + G
Sbjct: 266 GHRGFSGLDGAKGDAGPAGPKGEPGSPGENGAPGQMGPRGLPGERGRPGAPGPAGARGND 325
Query: 317 GSIVGAYAGYPSQFVPGLDPSKSGLVGGQLSGGLGLPPGK--------PPSSSPLTGASP 368
G+ GA AG P P P G VG + G P G P GA+
Sbjct: 326 GA-TGA-AGPPGPTGPAGPPGFPGAVGAKGEAGPQGPRGSEGPQGVRGEPGPPGPAGAAG 383
Query: 369 PSFLQGLCRDPYCLGGYHGASHLGGSSCSTCSAHDPAGPSLKAGGYPLVYPGHPLQPAAL 428
P+ G P G +GA + G+ A P+GP PG P P
Sbjct: 384 PAGNPGADGQPGAKGA-NGAPGIAGAP-GFPGARGPSGPQ---------GPGGPPGPKGN 432
Query: 429 SSSAAQAALPGHPLYTYGFMLQNEPLPHSCNWVAASGPCDKRFATSEELLSHLRTHTALP 488
S PG P + EP P V GP + T LP
Sbjct: 433 SGE------PGAPGSKGDTGAKGEPGP-----VGVQGPPGPAGEEGKRGARGEPGPTGLP 481
Query: 489 GAEKLLA-----AYPGASGLGSAAAAAAAAASCHLHLPPPAAP-GSPG 530
G +PGA G+ A S P PA P GSPG
Sbjct: 482 GPPGERGGPGSRGFPGADGVAGPKGPAGERGS-----PGPAGPKGSPG 524
Score = 47.4 bits (111), Expect = 4e-05
Identities = 92/344 (26%), Positives = 112/344 (32%), Gaps = 29/344 (8%)
Query: 105 PPSSKLNSVAAAANGLGAEKDPGRSAPGAASAAAALKQLGDSPAEDKSSFKPYSKGSGGG 164
P ++ N A A G P PG A A + G P + S P +G G
Sbjct: 318 PAGARGNDGATGAAGPPGPTGPA-GPPGFPGAVGAKGEAG--PQGPRGSEGP--QGVRGE 372
Query: 165 DSRKDSGSSSVSSTSSSSSSSPGDKAGFRVPSAACPPFPPHGAPVSASSSSSSPGGSRGG 224
++ + + + PG K P A P P S P G +G
Sbjct: 373 PGPPGPAGAAGPAGNPGADGQPGAKGANGAPGIAGAPGFPGARGPSGPQGPGGPPGPKGN 432
Query: 225 SPHHSDCKNGGGVGG-GELDKKDQEPKPSPEPAAVSRGGGGEPGAHGGAESGASGRKSEP 283
S + G G GE + P P RG GEPG G G G + P
Sbjct: 433 SGEPGAPGSKGDTGAKGEPGPVGVQGPPGPAGEEGKRGARGEPGPTG--LPGPPGERGGP 490
Query: 284 PS-ALVGAGHVA-PVSPYKPGHSVFPLPPSSIGYHGSIVGAYAGYPSQFVPGLDPSKSGL 341
S GA VA P P G P P G G AG P + GL P GL
Sbjct: 491 GSRGFPGADGVAGPKGP--AGERGSPGPAGPKGSPGE-----AGRPGE--AGL-PGAKGL 540
Query: 342 VGGQLSGGLGLPPGK--PPSSSPLTGASPPSFLQGLCRDPYCLG--GYHGASHLGGSSCS 397
G S G P GK PP + G P G +G G GA+ G +
Sbjct: 541 TGSPGSPG---PDGKTGPPGPAGQDGRPGPPGPPGARGQAGVMGFPGPKGAAGEPGKAGE 597
Query: 398 TCSAHDP--AGPSLKAGGYPLVYPGHPLQPAALSSSAAQAALPG 439
P GP+ K G P P PA A PG
Sbjct: 598 RGVPGPPGAVGPAGKDGEAGAQGPPGPAGPAGERGEQGPAGSPG 641
Score = 43.1 bits (100), Expect = 7e-04
Identities = 101/427 (23%), Positives = 133/427 (31%), Gaps = 98/427 (22%)
Query: 100 GKPDPPPSSKLNSVAAAANGLGAEKDPGRSA-------PGAASAAAALKQLGDSPAEDKS 152
G+P PP + A GA+ +PG + PG A A +G+ A
Sbjct: 803 GEPGPPGPAGFAGPPGADGQPGAKGEPGDAGAKGDAGPPGPAGPAGPPGPIGNVGAPGAK 862
Query: 153 SFKPYSKGSGG--GDSRKDSGSSSVSSTSSSSSSSP----------------GDKAGFRV 194
++GS G G + + V S ++ P G+
Sbjct: 863 G----ARGSAGPPGATGFPGAAGRVGPPGPSGNAGPPGPPGPAGKEGGKGPRGETGPAGR 918
Query: 195 PSAACPPFPPHGAPVSASSSSSSPGGSRGGSPHHSDCKNGGGVGGGELDKKDQE----PK 250
P PP PP A S + P G+ G+P GV G + ++ P
Sbjct: 919 PGEVGPPGPPGPAGEKGSPGADGPAGA-PGTPGPQGIAGQRGVVGLPGQRGERGFPGLPG 977
Query: 251 PSPEPAAVSRGGG----GEPGAHG----GAESGASGRKSEP-----------PSALVGAG 291
PS EP G G PG G G SGR+ P P A G
Sbjct: 978 PSGEPGKQGPSGASGERGPPGPMGPPGLAGPPGESGREGAPGAEGSPGRDGSPGAKGDRG 1037
Query: 292 HVAPVSPYKPGHSVFPLPPSSIGYHGSI-----------------VGAYAGYPSQFVPG- 333
P P PG P P +G G VGA Q G
Sbjct: 1038 ETGPAGP--PGAPGAPGAPGPVGPAGKSGDRGETGPAGPAGPVGPVGARGPAGPQGPRGD 1095
Query: 334 ----LDPSKSGLVGGQLSGGLGLPPGKP--PSSSPLTGASPPSFLQGLCRDPYCLGGYHG 387
+ G+ G + GL PPG P P +GAS P+ +G P G G
Sbjct: 1096 KGETGEQGDRGIKGHRGFSGLQGPPGPPGSPGEQGPSGASGPAGPRG----PPGSAGAPG 1151
Query: 388 ASHLGGSSCSTCSAHDPAGPSLKAG-GYPLVYPGHPLQPAALSSSAAQAALPGHPLYTYG 446
L G P GP + G P+ PG P P PG P +
Sbjct: 1152 KDGLNGLP----GPIGPPGPRGRTGDAGPVGPPGPPGPPGP----------PGPPSAGFD 1197
Query: 447 FMLQNEP 453
F +P
Sbjct: 1198 FSFLPQP 1204
Score = 40.8 bits (94), Expect = 0.004
Identities = 92/377 (24%), Positives = 112/377 (29%), Gaps = 72/377 (19%)
Query: 191 GFRVPSAACPPFPPHGAP---------VSASSSSSSPGGSRG--GSPHHSDCKNGGGVGG 239
G VP C P P G+ V + P G RG G P G+ G
Sbjct: 83 GAEVPEGECCPVCPDGSESPTDQETTGVEGPKGDTGPRGPRGPAGPPGRDGIPGQPGLPG 142
Query: 240 GELDKKDQEPKPSPEPAAVSRGGGGEPGAHGGAESGASGRKSEPPSALVGAGHVAPVSPY 299
P P P GG P G + ++G S P P P
Sbjct: 143 --------PPGPPGPPGPPGLGGNFAPQLSYGYDEKSTGGISVPGPMGPSGPRGLPGPPG 194
Query: 300 KPGHSVFPLPPSSIGYHGSIVGAYAGYPSQFVPGLDPSKSGLVGGQLSGGLGLPPGKPPS 359
PG F PP G G+ +G P P K+G G PG+P
Sbjct: 195 APGPQGFQGPPGEPGEPGA-----SGPMGPRGPPGPPGKNG------DDGEAGKPGRPGE 243
Query: 360 SSPLTGASPPSFLQGLCRDPYCLGGYHGASHLGGSSCSTCSAHDPAGPSLKAGG------ 413
P G L G P + G+ G S L G+ PAGP + G
Sbjct: 244 RGP-PGPQGARGLPGTAGLP-GMKGHRGFSGLDGAKGDA----GPAGPKGEPGSPGENGA 297
Query: 414 ----YPLVYPGHPLQPAALSSSAAQ-------AALPGHPLYTYGFMLQNEPLPHSCNWVA 462
P PG +P A + A+ AA P P G P V
Sbjct: 298 PGQMGPRGLPGERGRPGAPGPAGARGNDGATGAAGPPGPTGPAG-------PPGFPGAVG 350
Query: 463 ASGPCDKRFATSEELLSHLRTHTALPGAEKLL--AAYPGASGLGSAAAAAAAAASCHLHL 520
A G + E +R PG A PGA G A A A
Sbjct: 351 AKGEAGPQGPRGSEGPQGVRGEPGPPGPAGAAGPAGNPGADGQPGAKGANGA-------- 402
Query: 521 PPPAAPGSPGSLSLRNP 537
P G+PG R P
Sbjct: 403 --PGIAGAPGFPGARGP 417
>gi|148237270 hypermethylated in cancer 1 isoform 2 [Homo sapiens]
Length = 733
Score = 55.8 bits (133), Expect = 1e-07
Identities = 111/436 (25%), Positives = 144/436 (33%), Gaps = 107/436 (24%)
Query: 112 SVAAAANGLGAEKDPGRSAPGAASAAAALKQLGDSPAEDKSSFKPYSK-------GSGGG 164
+ AAAA GAE + GA AAA+ Q+ D A K K + K G GGG
Sbjct: 112 AAAAAAVAPGAEP-----SLGAVLAAASYLQIPDLVALCKKRLKRHGKYCHLRGGGGGGG 166
Query: 165 D----SRKDSGSSSVSSTSSSSSSSPGDKAGFRVPSAACPPFPPHGAPVS--ASSSSSSP 218
R G + + + SP G P AA PP P A + A +S P
Sbjct: 167 GYAPYGRPGRGLRAATPVIQACYPSP---VGPPPPPAAEPPSGPEAAVNTHCAELYASGP 223
Query: 219 GGSRGGSPHHSDCKNGGGVGGGELDKKDQEPKPSPEPAAVSRGGGGEPGAHGGAESGASG 278
G + C G+ +L KK +PE R P + A A
Sbjct: 224 GPAAALCASERRCSPLCGL---DLSKKSPPGSAAPERPLAERELPPRPDSPPSAGPAAY- 279
Query: 279 RKSEPPSALVGAGHVA---------PVSPYKPGH-SVFPLPPS----------------S 312
EPP AL + P P++ G S P PP
Sbjct: 280 --KEPPLALPSLPPLPFQKLEEAAPPSDPFRGGSGSPGPEPPGRPDGPSLLYRWMKHEPG 337
Query: 313 IGYHGSIVGAYAGYPSQFVPGLDPSKSGLVGGQLSGGLGLPPGKPPSSSPLTGASPPSFL 372
+G +G +G G PS+ + G + PG PP G +PP
Sbjct: 338 LGSYGDELGRERGSPSERCE------------ERGGDAAVSPGGPP-----LGLAPPPRY 380
Query: 373 QGLCRDPYCLGGYHGASHLGGSSCSTCSAHDPAGPSLKAGGYPLVYPGHPLQPAALSSSA 432
G P G SS T S+ DP+ P GYP
Sbjct: 381 PGSLDGP---GAGGDGDDYKSSSEETGSSEDPSPPGGHLEGYPC---------------- 421
Query: 433 AQAALPGHPLYTYGFMLQNEPLPHSCNWVAASGPCDKRFATSEELLSHLRTHT----ALP 488
P YG EP N PC K F +SE+L +H+ H AL
Sbjct: 422 --------PHLAYG-----EPESFGDNLYVCI-PCGKGFPSSEQLNAHVEAHVEEEEALY 467
Query: 489 GAEKLLAAYPGASGLG 504
G + GA+GLG
Sbjct: 468 GRAEAAEVAAGAAGLG 483
>gi|61676186 hypermethylated in cancer 1 isoform 1 [Homo sapiens]
Length = 714
Score = 55.8 bits (133), Expect = 1e-07
Identities = 111/436 (25%), Positives = 144/436 (33%), Gaps = 107/436 (24%)
Query: 112 SVAAAANGLGAEKDPGRSAPGAASAAAALKQLGDSPAEDKSSFKPYSK-------GSGGG 164
+ AAAA GAE + GA AAA+ Q+ D A K K + K G GGG
Sbjct: 93 AAAAAAVAPGAEP-----SLGAVLAAASYLQIPDLVALCKKRLKRHGKYCHLRGGGGGGG 147
Query: 165 D----SRKDSGSSSVSSTSSSSSSSPGDKAGFRVPSAACPPFPPHGAPVS--ASSSSSSP 218
R G + + + SP G P AA PP P A + A +S P
Sbjct: 148 GYAPYGRPGRGLRAATPVIQACYPSP---VGPPPPPAAEPPSGPEAAVNTHCAELYASGP 204
Query: 219 GGSRGGSPHHSDCKNGGGVGGGELDKKDQEPKPSPEPAAVSRGGGGEPGAHGGAESGASG 278
G + C G+ +L KK +PE R P + A A
Sbjct: 205 GPAAALCASERRCSPLCGL---DLSKKSPPGSAAPERPLAERELPPRPDSPPSAGPAAY- 260
Query: 279 RKSEPPSALVGAGHVA---------PVSPYKPGH-SVFPLPPS----------------S 312
EPP AL + P P++ G S P PP
Sbjct: 261 --KEPPLALPSLPPLPFQKLEEAAPPSDPFRGGSGSPGPEPPGRPDGPSLLYRWMKHEPG 318
Query: 313 IGYHGSIVGAYAGYPSQFVPGLDPSKSGLVGGQLSGGLGLPPGKPPSSSPLTGASPPSFL 372
+G +G +G G PS+ + G + PG PP G +PP
Sbjct: 319 LGSYGDELGRERGSPSERCE------------ERGGDAAVSPGGPP-----LGLAPPPRY 361
Query: 373 QGLCRDPYCLGGYHGASHLGGSSCSTCSAHDPAGPSLKAGGYPLVYPGHPLQPAALSSSA 432
G P G SS T S+ DP+ P GYP
Sbjct: 362 PGSLDGP---GAGGDGDDYKSSSEETGSSEDPSPPGGHLEGYPC---------------- 402
Query: 433 AQAALPGHPLYTYGFMLQNEPLPHSCNWVAASGPCDKRFATSEELLSHLRTHT----ALP 488
P YG EP N PC K F +SE+L +H+ H AL
Sbjct: 403 --------PHLAYG-----EPESFGDNLYVCI-PCGKGFPSSEQLNAHVEAHVEEEEALY 448
Query: 489 GAEKLLAAYPGASGLG 504
G + GA+GLG
Sbjct: 449 GRAEAAEVAAGAAGLG 464
>gi|163965366 nascent polypeptide-associated complex alpha subunit
isoform a [Homo sapiens]
Length = 2078
Score = 55.5 bits (132), Expect = 1e-07
Identities = 147/590 (24%), Positives = 193/590 (32%), Gaps = 95/590 (16%)
Query: 2 SDSPAGSNPRTPESSGSGSGGGGKRPAVPAAVSLLPPADPLRQANRLPIRVLKML----S 57
S SP G + +P++ + G P P +L P P+ +A+ LP L S
Sbjct: 793 SPSPLGVSV-SPQTKRPPTKKGSAGPDTPIG-NLSSPVSPV-EASFLPENSLSFQGSKDS 849
Query: 58 AHTGHLLHPEYLQPLSSTPVSPIELDAKKSPLALLAQTCSQIGKPDPPPSSKLNSVAAAA 117
T H S TP SP K +P S G PP + SV
Sbjct: 850 PATTH----------SPTPPSP-----KGAPTPSAVTPLSPKGVTLPPKETPTPSVV--- 891
Query: 118 NGLGAEKDPGRSAPGAASAAAALKQLGDSPAEDKSSFKPYSKGSGGGDSRKDSGSSSVSS 177
N ++ P AP A AL SP + +++ P KG S K +
Sbjct: 892 NLPFPKEGPATPAP---KQAPALSMTSSSPKKARAT--PAPKGIPASPSPK-------GA 939
Query: 178 TSSSSSSSPGDKAGFRVPSAACPPFPPHGAPVSASSSSSSPGGSRGGSPHHSDCKNGGGV 237
+ +++ P K G PS P PP P S ++P S G+P
Sbjct: 940 PTPPAATPPSPKGGPATPSPKWAPTPPAATPPSPKGGPATP--SPKGAPTPPAATPPSPK 997
Query: 238 GGGELDKKDQEPKPSPEPAAVSRGGGGEPGAHGGAESGASGRKSEPPSALVGAGHVAPVS 297
GG PK +P P AV+ A GAS + P + G+ P+
Sbjct: 998 GG----PATPSPKGAPTPPAVTPPSPKGSPAATPFPKGASTPPAATPPSPKGSPAATPLP 1053
Query: 298 PYKPGHSVFPLP-----PSSIGYHGSIVGAYAGYPSQFVPGLDPSKSG------LVGGQL 346
P LP P++ G+ A PS PS G
Sbjct: 1054 KGAPTTPAATLPSPKGGPATPSLKGAPTPPAATPPSPKGGPATPSPKGAPMPPAATPPSP 1113
Query: 347 SGGLGLPPGKPPSSSPLTGASPPSFLQGLCRDPYCLGGYHGASHLGGSSCSTCSAHDPAG 406
GGL PP K ++P A+PPS GL P T A P
Sbjct: 1114 KGGLATPPHKGAPTTP--AATPPSPKGGLATPP-------------PKGAPTTPAATPPS 1158
Query: 407 PSLKAGGYPLVYP-GHPLQPAALSSSAAQAALPGHPLYTYGFMLQNEPLPHSC-NWVAAS 464
P GG P G P PAA S P L T P P AA+
Sbjct: 1159 PK---GGLATPPPKGAPTTPAATPPS------PKGGLAT--------PSPKGAPTTPAAT 1201
Query: 465 GPCDKRFATSEELLSHLRTHTALPGAEKLLAAYPGASGLGSAAAAAAAAASCHLHLPPP- 523
P K + T A P + K A P G + AA + PPP
Sbjct: 1202 PPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGPATPPPK 1261
Query: 524 AAPGSPGSLSLRNPHTLGLSRYHPYGKSHLSTAGGLAVPSLPTAGPYYSP 573
AP P + P +L P K + A + P P GP SP
Sbjct: 1262 GAPTPPAA----TPPSLKGGLATPPHKGAPNPA--VVTPPSPKGGPATSP 1305
Score = 38.1 bits (87), Expect = 0.023
Identities = 140/594 (23%), Positives = 198/594 (33%), Gaps = 117/594 (19%)
Query: 1 MSDSPAGSNPRTPESSGSGSGGGGKRPAVPAAVSLLPPADPLRQANRLPIRVLKMLSAHT 60
++ P P TP ++ GG P P P A P +
Sbjct: 1117 LATPPHKGAPTTPAATPPSPKGGLATPP-PKGAPTTPAATP---------------PSPK 1160
Query: 61 GHLLHPEYLQPLSSTPVSPIELDAKKSPLALLAQTCSQIGKPDPP----PSSKLNSVAAA 116
G L P P P +P SP LA T S G P P PS K A
Sbjct: 1161 GGLATP----PPKGAPTTPAA--TPPSPKGGLA-TPSPKGAPTTPAATPPSPK--GGLAT 1211
Query: 117 ANGLGAEKDPGRSAPGAASAAAALKQLGDSPAEDKSSFKPYSKGSGGGDSRKDSGSSSVS 176
+ GA P + P A G +P ++ P KG K + + +
Sbjct: 1212 PSPKGAPTTPAATPPSPKGGLATPSPKG-APTTPAAT-PPSPKGGPATPPPKGAPTPPAA 1269
Query: 177 STSSSSS--SSPGDKAGFRVPSAACPPFP--------PHGAPVSASSSSSSPGGSRGGSP 226
+ S ++P K G P+ PP P P GAP +++ SP GS G P
Sbjct: 1270 TPPSLKGGLATPPHK-GAPNPAVVTPPSPKGGPATSPPKGAPTPPAATPPSPKGSPGTPP 1328
Query: 227 HHSDCKNGGGVGGGELDKKDQEPKPSPEPAAVS-RGGGGEPGAHGGAESGASGRKSEPPS 285
PK +P P AV+ G P S G + PS
Sbjct: 1329 ----------------------PKGAPTPPAVTPPSPKGTPTLPATTPSSKGGPTT--PS 1364
Query: 286 ALVGAGHVAPVSPYKPGHSVFPLPPSSIGYHGSIVGAYAGYPSQFVPGLDPSKSGLVGGQ 345
+ G A +K G ++ P P G + + G P+ P + P
Sbjct: 1365 SKEGPTPPAATPSHKGGPAMTPPSPK----RGPAIPSPKGDPTS--PAVIP--------- 1409
Query: 346 LSGGLGLPPGKPPSSSPLT--GASPPS--FLQGLCRDPYCLGGYHGASHLGGSSCSTCSA 401
L P K P ++P+T GA+ PS L P L S G + S
Sbjct: 1410 ------LSPKKAP-ATPVTREGAATPSKGDLTPPAVTPVSLKKAPATSAPKGGPATPSSK 1462
Query: 402 HDPAGPSLKAGGYPLVYPGHPLQPAALSSSAAQAALPGHPLYTYGFMLQNEPLPHSCNWV 461
DP P++ P P P +++S++ P P G +P S V
Sbjct: 1463 GDPTLPAVTPPS-----PKEPPAPKQVATSSSPKKAPATPA-PMGAPTLPAVIPSSPKEV 1516
Query: 462 AASGPCDKR--FATSEELLSHLRTHTALPGAEKLLAAYPGASGLGSAAAAAAAAASCHLH 519
A+ P +R A + LLS +T L E L+ P A + S A
Sbjct: 1517 PAT-PSSRRDPIAPTATLLSK-KTPATLAPKEALI---PPAMTVPSPKKTPAIPT----- 1566
Query: 520 LPPPAAPGSPGSLSLRNPHTLGLSRYHPYGKSHLSTAGGLAVPSLPTAGPYYSP 573
P AP +P S +P + S Y K S L P++ + P +P
Sbjct: 1567 --PKEAPATPSSKEASSPPAVTPSTY----KGAPSPKELLIPPAVTSPSPKEAP 1614
>gi|33946327 nucleoporin 214kDa [Homo sapiens]
Length = 2090
Score = 54.7 bits (130), Expect = 2e-07
Identities = 123/559 (22%), Positives = 189/559 (33%), Gaps = 92/559 (16%)
Query: 75 TPVSPIELDAKKSPLALLAQTCSQIGKPDPPPSSKLNSVAAAANGLGAEKDP-------G 127
+P PI + AL Q SQ + S L +V N + +P G
Sbjct: 1081 SPSHPISAPQAAAAAALRRQMASQAPAVNTLTESTLKNVPQVVNVQELKNNPATPSTAMG 1140
Query: 128 RSAP--GAASAAAALKQLGDSPAEDKS---SFKPYSKGSGGGDSRKDSGSSSVSSTSSSS 182
S P A + L + + A+ S S KP G +S + ++
Sbjct: 1141 SSVPYSTAKTPHPVLTPVAANQAKQGSLINSLKPSGPTPASGQLSSGDKASGTAKIETAV 1200
Query: 183 SSSPGDKAGFRVPSAACPPFPPHGAPVSASSSSSSPGGSRGGSP--HHSDCKNGGGVGGG 240
+S+P F P + P + + SS+ ++G +P S + GGG
Sbjct: 1201 TSTPSASGQFSKPFSFSPSGTGFNFGIITPTPSSNFTAAQGATPSTKESSQPDAFSSGGG 1260
Query: 241 ELDKKDQEPKPSPEPAAVSRGGGGEPGAHGGAESGASGRKSEPPS--ALVGAGHVAPVSP 298
+ P+ SP P+ ++ PG E AS + PS AL P
Sbjct: 1261 SKPSYEAIPESSP-PSGITSASNTTPG-----EPAASSSRPVAPSGTALSTTSSKLETPP 1314
Query: 299 YKPGHSVFPLPPSSIGYHGSIVGAYAGY-----PSQFVPGLDPSKSGLVGGQLSGGLGLP 353
K G +F PSS+ G +G+++G P S + L Q + G+P
Sbjct: 1315 SKLGELLF---PSSLA--GETLGSFSGLRVGQADDSTKPTNKASSTSLTSTQPTKTSGVP 1369
Query: 354 PG-------------KPP--SSSPLTGASPPSFLQGLCRD-----PYCLGGYHGASHLGG 393
G +PP SS+ T +PP+ P G G GG
Sbjct: 1370 SGFNFTAPPVLGKHTEPPVTSSATTTSVAPPAATSTSSTAVFGSLPVTSAGSSGVISFGG 1429
Query: 394 SSCS------------TCSAHDPAGPSLKAGGYPLVYPGHPLQPAALSSSAAQAALPGHP 441
+S S T S P+ P PL L +L SSA +LP
Sbjct: 1430 TSLSAGKTSFSFGSQQTNSTVPPSAPPPTTAATPLPTSFPTLSFGSLLSSATTPSLP--- 1486
Query: 442 LYTYGFMLQNEPLPHSCNWVAASGPCDKRFATSEELLSHLRTHTALPGA---------EK 492
M + + P D + S L + LP A ++
Sbjct: 1487 ------MSAGRSTEEATSSALPEKPGDSEVSASAASLLEEQQSAQLPQAPPQTSDSVKKE 1540
Query: 493 LLAAYPGASGLGSAAAAAAAAASCHLHLPPPAAPGSPGSLSLRNPHTLGLSRYHPYGK-- 550
+ A P S G+AA++ + A L A P + G R S + G+
Sbjct: 1541 PVLAQPAVSNSGTAASSTSLVA-----LSAEATPATTGVPDARTEAVPPASSFSVPGQTA 1595
Query: 551 ---SHLSTAGGLAVPSLPT 566
+ +S+AG +AV + T
Sbjct: 1596 VTAAAISSAGPVAVETSST 1614
Score = 42.4 bits (98), Expect = 0.001
Identities = 103/436 (23%), Positives = 146/436 (33%), Gaps = 56/436 (12%)
Query: 5 PAGSNPRTPESSGS----GSGGGGKRPAVP-AAVSLLPPADPLRQANRLPIRVLKMLSAH 59
PA SN T SS S + VP A +PPA + + + SA
Sbjct: 1546 PAVSNSGTAASSTSLVALSAEATPATTGVPDARTEAVPPASSFSVPGQTAVTAAAISSA- 1604
Query: 60 TGHLLHPEYLQPLSSTPVSPIELDAKKSPLALLAQTCSQIGKPDPPPSSK-------LNS 112
G + P++S+ S + A T PP +S N+
Sbjct: 1605 -GPVAVETSSTPIASSTTSIVAPGPSAEAAAFGTVTSGSSVFAQPPAASSSSAFNQLTNN 1663
Query: 113 VAAAANG------LGAEKDP---GRSAPGAASAAAALKQLGDS----PAEDKSSFKPYSK 159
A A + + A P G+ AS AAA Q+ S PA ++ + +
Sbjct: 1664 TATAPSATPVFGQVAASTAPSLFGQQTGSTASTAAATPQVSSSGFSSPAFGTTAPGVFGQ 1723
Query: 160 GSGGGDSRKDSGSSSVSSTSSSSSSSPGDKAGFRVPSAACPPFPPHGAPVSASSSSSSPG 219
+ G S +SS +S S S F P+++ P +ASS+SSS
Sbjct: 1724 TTFGQASVFGQSASSAASVFSFSQPGFSSVPAFGQPASSTPTSTSGSVFGAASSTSSSSS 1783
Query: 220 GSRGGSPHHSDCKNGGGVGGGELDKKDQEPKPSPEPAAVSRGGGGEPGAHGGAESGASGR 279
S G S GGG+ G S PA G G+ G+ G S A+
Sbjct: 1784 FSFG----QSSPNTGGGLFG-----------QSNAPAFGQSPGFGQGGSVFGGTSAAT-- 1826
Query: 280 KSEPPSALVGAGHVAPVSPYKPGHSVFPLPPSSIGYHGSIVGAYAGYPSQFVPG--LDPS 337
+A S + ++ S G S G G S G
Sbjct: 1827 ----TTAATSGFSFCQASGFGSSNT-----GSVFGQAASTGGIVFGQQSSSSSGSVFGSG 1877
Query: 338 KSGLVGGQLSGGLGLPPGKPPSSSPLTGASPPSFLQGLCRDPYCLGGYHGASHLGGSSCS 397
+G GG SG G P + +P + AS F + L G GA GG + S
Sbjct: 1878 NTGRGGGFFSGLGGKPSQDAANKNPFSSAS-GGFGSTATSNTSNLFGNSGAKTFGGFASS 1936
Query: 398 TCSAHDPAGPSLKAGG 413
+ P G GG
Sbjct: 1937 SFGEQKPTGTFSSGGG 1952
Score = 37.7 bits (86), Expect = 0.030
Identities = 70/297 (23%), Positives = 103/297 (34%), Gaps = 45/297 (15%)
Query: 7 GSNPRTPESSGSGSGGGGKRPAVPAAVSLLPPADPLRQANRLPI-----------RVLKM 55
GS P TP SS + A PA++ PA P+ + LP LK
Sbjct: 432 GSTPTTPTSSQAPQKLDASAAAAPASLPPSSPAAPIATFSLLPAGGAPTVFSFGSSSLKS 491
Query: 56 LSAHTGHLLHPEYLQPLSSTPVSPIELDAKKSPLALLAQTCSQIGKPDPPPSSKLNSVAA 115
+ TG P Y S+ +P S + + + + + P P S S A+
Sbjct: 492 SATVTGE--PPSYSSGSDSSKAAP---GPGPSTFSFVPPSKASLA-PTPAASPVAPSAAS 545
Query: 116 AANGLGAEKDPGRSAPGAASAAAALKQLGDSPAEDKSSFKPYSKGSGGGDSRKDSGSSSV 175
+ G K S P + +A + K SF P + S K + +++
Sbjct: 546 FSFGSSGFKPTLESTPVPSVSAPNIAM--------KPSFPPSTSAVKVNLSEKFTAAATS 597
Query: 176 SSTSSSSSSSPGDKAGFRVPSAACPPFPPHGAPVSASSSSSSPGGSRGGSPHHSDCKNGG 235
+ SSS S+ P AA P H P+SA SS S SP
Sbjct: 598 TPVSSSQSAPPMSPFSSASKPAASGPL-SHPTPLSAPPSSVPLKSSVLPSP--------- 647
Query: 236 GVGGGELDKKDQEPKPSPEPAAVSRGGGGEPGAHGGAESGASGRKSEPPSALVGAGH 292
+ + SP P+ V + P A A+ G+ KS P+ GH
Sbjct: 648 -------SGRSAQGSSSPVPSMVQKSPRITPPA---AKPGSPQAKSLQPAVAEKQGH 694
Score = 35.4 bits (80), Expect = 0.15
Identities = 70/271 (25%), Positives = 100/271 (36%), Gaps = 44/271 (16%)
Query: 274 SGASGRKSEPPSALVGAGHVAPVSPYKPGHSVFPLPPSSIGYHGSIVGAYAGYPSQFVPG 333
S A+ S PPS+ + P +VF SS+ ++ G Y S G
Sbjct: 450 SAAAAPASLPPSSPAAPIATFSLLPAGGAPTVFSFGSSSLKSSATVTGEPPSYSS----G 505
Query: 334 LDPSKSGLVGGQLSGGLGLPPGKPPSSSPLTGASP--PSFLQGLCRDPYCLGGYHGASHL 391
D SK+ G + +PP K S +P ASP PS AS
Sbjct: 506 SDSSKAAPGPGPSTFSF-VPPSKA-SLAPTPAASPVAPS----------------AASFS 547
Query: 392 GGSSCSTCSAHDPAGPSLKAGGYPLVYPGHPLQPAALSSSAAQ---AALPGHPLYTYGFM 448
GSS + PS+ A + P P +A+ + ++ AA P+ +
Sbjct: 548 FGSSGFKPTLESTPVPSVSAPNIAMK-PSFPPSTSAVKVNLSEKFTAAATSTPVSSSQSA 606
Query: 449 LQNEPLPHSCNWVAASGPCDKRFATSEELLSHLRTHTALPGAEKL----LAAYPGASGLG 504
P S + AASGP LSH +A P + L L + G S G
Sbjct: 607 PPMSPFS-SASKPAASGP-----------LSHPTPLSAPPSSVPLKSSVLPSPSGRSAQG 654
Query: 505 SAAAAAAAAASCHLHLPPPAAPGSPGSLSLR 535
S++ + PP A PGSP + SL+
Sbjct: 655 SSSPVPSMVQKSPRITPPAAKPGSPQAKSLQ 685
Score = 34.3 bits (77), Expect = 0.33
Identities = 83/337 (24%), Positives = 109/337 (32%), Gaps = 54/337 (16%)
Query: 73 SSTPVSPIELDAKKSPLALLAQTCSQIGKPDPPPSSKLNSVAAAANGLGAEKDPGRSAPG 132
S+TPV ++ A +P QT S P + ++ A G A G++ G
Sbjct: 1669 SATPVFG-QVAASTAPSLFGQQTGSTASTAAATPQVSSSGFSSPAFGTTAPGVFGQTTFG 1727
Query: 133 AASAAAALKQLGDSPAEDKSSFKPYSKGSGG-------GDSRKDSGSSSVSSTSSSSSSS 185
AS G S + S F G S S S SV +SS+SSS
Sbjct: 1728 QASV------FGQSASSAASVFSFSQPGFSSVPAFGQPASSTPTSTSGSVFGAASSTSSS 1781
Query: 186 PGDKAGFRVPSAACPPFPPHGAPVSASSSSSSPGGSRGG----------SPHHSDCK--- 232
G P+ F AP S GGS G + S C+
Sbjct: 1782 SSFSFGQSSPNTGGGLFGQSNAPAFGQSPGFGQGGSVFGGTSAATTTAATSGFSFCQASG 1841
Query: 233 ----NGGGVGGGELDKKDQEPKPSPEPAAVSRGGGGEPGAHGGAESGASGRKSEPPSALV 288
N G V G ++ S G G G GG SG G+ S+
Sbjct: 1842 FGSSNTGSVFGQAASTGGIVFGQQSSSSSGSVFGSGNTGRGGGFFSGLGGKPSQ------ 1895
Query: 289 GAGHVAPVSPYKPGHSVFPLPPSSIGYHGSIVGAYAGYPS-----QFVPGLDPSKSGLVG 343
A + P S G +S + S + G+ S Q G S G V
Sbjct: 1896 DAANKNPFSSASGGFGSTATSNTSNLFGNSGAKTFGGFASSSFGEQKPTGTFSSGGGSVA 1955
Query: 344 GQ--------LSGGLGLPP--GKPPS--SSPLTGASP 368
Q +GG G P G PP+ SP G P
Sbjct: 1956 SQGFGFSSPNKTGGFGAAPVFGSPPTFGGSPGFGGVP 1992
Score = 32.7 bits (73), Expect = 0.96
Identities = 38/144 (26%), Positives = 56/144 (38%), Gaps = 17/144 (11%)
Query: 143 LGDSPAEDKSSFKPYSKGSGGGDSRKDSGSSSVSSTSSSSS--SSPGDKAGFRVPSAACP 200
LG P++D ++ P+S SGG S S +S++ S + + G + P+
Sbjct: 1889 LGGKPSQDAANKNPFSSASGGFGSTATSNTSNLFGNSGAKTFGGFASSSFGEQKPTGT-- 1946
Query: 201 PFPPHGAPVSAS----SSSSSPGGSRGGSPHHSDCKNGGGVGGGELDKKDQEPKPSPEPA 256
F G V++ SS + GG S GG G G + P PA
Sbjct: 1947 -FSSGGGSVASQGFGFSSPNKTGGFGAAPVFGSPPTFGGSPGFGGV------PAFGSAPA 1999
Query: 257 AVSRGG--GGEPGAHGGAESGASG 278
S G GG+ G A + A G
Sbjct: 2000 FTSPLGSTGGKVFGEGTAAASAGG 2023
>gi|28559039 mediator complex subunit 1 [Homo sapiens]
Length = 1581
Score = 54.7 bits (130), Expect = 2e-07
Identities = 65/258 (25%), Positives = 98/258 (37%), Gaps = 31/258 (12%)
Query: 144 GDSPAEDKSSFKPYSKGSGGGDSRKDSGSSSVSSTSSSSSSSPGDKAGFRVPSAACPPFP 203
G SP+ S+ +P++ + G S K GS+ S T ++ P K ++P
Sbjct: 1019 GKSPSHSSSN-RPFTPPTSTGGS-KSPGSAGRSQTPPGVATPPIPKITIQIPKGTVMVGK 1076
Query: 204 PHGAPVSASSSSSSPGGSRGGSPHHSDCKNGGGVGGGELDKKDQEPKPSPEPAAV--SRG 261
P SS S S GS+ H S + G K + S +++ S+G
Sbjct: 1077 PSSHSQYTSSGSVSSSGSKSHHSHSSSSSSSASTSGKMKSSKSEGSSSSKLSSSMYSSQG 1136
Query: 262 GGGEPGAHGGAESGASGRKSEPPSALVGAGHVAPVSPYKPGHSVFPLPPSSIGYHGSIVG 321
G + ++SG G+ P G + + KP PSS+
Sbjct: 1137 SSGSSQSKNSSQSG--GKPGSSPITKHGLSSGSSSTKMKPQGK-----PSSL-------- 1181
Query: 322 AYAGYPSQFVPGLDPSKSGLVGG--QLSGGLGLPPGKPPSS---SPLTGASPPSFLQGLC 376
PS P + PS S GG +L+ + PG PPSS SP++ S S + G
Sbjct: 1182 ---MNPSLSKPNISPSHSRPPGGSDKLASPMKPVPGTPPSSKAKSPISSGSGGSHMSGTS 1238
Query: 377 RDPYCLGGYHGASHLGGS 394
G +S LG S
Sbjct: 1239 SS----SGMKSSSGLGSS 1252
Score = 48.1 bits (113), Expect = 2e-05
Identities = 53/191 (27%), Positives = 75/191 (39%), Gaps = 31/191 (16%)
Query: 101 KPDPPPSSKLNSVAAAANGLGAEKDPGRSAP--GAASAAAALKQLGDSPAEDKSSFKPYS 158
KP PSS +N + N P S P G+ A+ +K + +P K+ P S
Sbjct: 1173 KPQGKPSSLMNPSLSKPN-----ISPSHSRPPGGSDKLASPMKPVPGTPPSSKAK-SPIS 1226
Query: 159 KGSGGGDSRKDSGSSSVSSTSSSSSSSPGDKAGFRVPSAACPPFPPHGAPVSASSSSSSP 218
GSGG S SS + S+S SS + PP +ASSSS S
Sbjct: 1227 SGSGGSHMSGTSSSSGMKSSSGLGSSG-----------SLSQKTPPSSNSCTASSSSFSS 1275
Query: 219 GGSRGGSPHHSDCKNGGGVGGGELDKKDQEPKPSP-----EPAAVSRGGGGEPGAHGGAE 273
GS S +N G G+ ++++P + + V+ G GGE G +
Sbjct: 1276 SGS-----SMSSSQNQHGSSKGKSPSRNKKPSLTAVIDKLKHGVVTSGPGGEDPLDG--Q 1328
Query: 274 SGASGRKSEPP 284
G S S P
Sbjct: 1329 MGVSTNSSSHP 1339
Score = 42.7 bits (99), Expect = 0.001
Identities = 55/233 (23%), Positives = 85/233 (36%), Gaps = 41/233 (17%)
Query: 99 IGKPDPPPSSKLNSVAAAANGLGAEKDPGRSAPGAASAAAALKQLGDSPAEDKSSFKPYS 158
+GKP S +S + +++G + S+ +AS + +K S
Sbjct: 1074 VGKPSSH-SQYTSSGSVSSSGSKSHHSHSSSSSSSASTSGKMKS---------------S 1117
Query: 159 KGSGGGDSRKDSGSSSVSSTSSSSSSSPGDKAGFRVPSAACPPFPPHGAPVSASSSSSSP 218
K G S+ SSS+ S+ SS SS + P HG +SS+ P
Sbjct: 1118 KSEGSSSSKL---SSSMYSSQGSSGSSQSKNSSQSGGKPGSSPITKHGLSSGSSSTKMKP 1174
Query: 219 GGSRGG-----------SPHHSDCKNGGGVGGGELDKKDQEPKPSPEPAAVSRG--GGGE 265
G SP HS GG + +P P P++ ++ G
Sbjct: 1175 QGKPSSLMNPSLSKPNISPSHS-----RPPGGSDKLASPMKPVPGTPPSSKAKSPISSGS 1229
Query: 266 PGAHGGAESGASGRKSEPPSALVGAGHVAPVSPYKPGHSVFPLPPSSIGYHGS 318
G+H S +SG KS S L +G ++ +P P + SS GS
Sbjct: 1230 GGSHMSGTSSSSGMKSS--SGLGSSGSLSQKTP--PSSNSCTASSSSFSSSGS 1278
>gi|186928827 dermokine isoform 5 precursor [Homo sapiens]
Length = 398
Score = 54.3 bits (129), Expect = 3e-07
Identities = 48/156 (30%), Positives = 62/156 (39%), Gaps = 25/156 (16%)
Query: 149 EDKSSFKPYSKGSGGGDSRKDSGSSSVSSTSSSSSSSPGDKAGFRVPSAACPPFPPHGAP 208
+++ P GSGGG S +SG S S + SS S S GD +G+
Sbjct: 225 QNEGCTNPPPSGSGGGSS--NSGGGSGSQSGSSGSGSNGDN--------------NNGSS 268
Query: 209 VSASSSSSSPGGSRGGSPHHSDCKNGG--GVGGGELDKKDQEPKPSPEPAAVSRGGGGEP 266
SSS SS GGS GGS S +GG G G E S G G +P
Sbjct: 269 SGGSSSGSSSGGSSGGSSGGSSGNSGGSRGDSGSESSWGSSTGSSSGNHGGSGGGNGHKP 328
Query: 267 G-------AHGGAESGASGRKSEPPSALVGAGHVAP 295
G A G ESG G + + S+ + +P
Sbjct: 329 GCEKPGNEARGSGESGIQGFRGQGVSSNMRNSETSP 364
Score = 43.1 bits (100), Expect = 7e-04
Identities = 38/141 (26%), Positives = 52/141 (36%), Gaps = 29/141 (20%)
Query: 100 GKPDPPPSSKLNSVAAAANGLGAEKDPGRSAPGAASAAAALKQLGDSPAEDKSSFKPYSK 159
G +PPPS + + G G++ +S + + + + SS S
Sbjct: 228 GCTNPPPSGSGGGSSNSGGGSGSQS--------GSSGSGSNGDNNNGSSSGGSSSGSSSG 279
Query: 160 GSGGGDSRKDSGSSSVSSTSSSSSSSPGDKAGFRVPSAACPPFPPHGAPVSASSSSSSPG 219
GS GG S SG+S S S S SS G G SSS + G
Sbjct: 280 GSSGGSSGGSSGNSGGSRGDSGSESSWGSSTG---------------------SSSGNHG 318
Query: 220 GSRGGSPHHSDCKNGGGVGGG 240
GS GG+ H C+ G G
Sbjct: 319 GSGGGNGHKPGCEKPGNEARG 339
Score = 33.1 bits (74), Expect = 0.73
Identities = 67/284 (23%), Positives = 96/284 (33%), Gaps = 31/284 (10%)
Query: 107 SSKLNSVAAAANGLGAEKDPGRSAPGA-----ASAAAALKQLGDS---PAED-------- 150
S L A G G + PG A A AA AL G AED
Sbjct: 68 SEALGQGTREAVGTGVRQVPGFGAADALGNRVGEAAHALGNTGHEIGRQAEDVIRHGADA 127
Query: 151 -KSSFKPYSKGSGGGDSRKDSGSSSVSSTSSSSSSSPGDKAGFRVPSAACPPFPPHGAPV 209
+ S++ +G ++ G S G+ G P +P + A
Sbjct: 128 VRGSWQGVPGHNGAWET--SGGHGIFGSQGGLGGQGQGNPGGLGTPWVH--GYPGNSAGS 183
Query: 210 SASSSSSSPGGSRG-GSPHHSDCKNGGGV---GGGELDKKDQEPKPSPEPAAVSRGGGGE 265
+ +P G G G P + G V G G + +Q + P + S GG
Sbjct: 184 FGMNPQGAPWGQGGNGGPPNFGTNTQGAVAQPGYGSVRASNQNEGCTNPPPSGSGGGSSN 243
Query: 266 PGAHGGAESGASGRKSEPPSALVGAGHVAPVSPYKPGHSVFPLPPSSIGYHGSIVGAYAG 325
G G++SG+SG S + + + G S SS G G+ G+
Sbjct: 244 SGGGSGSQSGSSGSGSNGDNNNGSSSGGSSSGSSSGGSS----GGSSGGSSGNSGGSRGD 299
Query: 326 YPSQFVPGLDPSKSGLVGGQLSGGLGLPPG--KPPSSSPLTGAS 367
S+ G S G GG G PG KP + + +G S
Sbjct: 300 SGSESSWGSSTGSSSGNHGGSGGGNGHKPGCEKPGNEARGSGES 343
>gi|47271406 bin3, bicoid-interacting 3 [Homo sapiens]
Length = 689
Score = 54.3 bits (129), Expect = 3e-07
Identities = 50/169 (29%), Positives = 69/169 (40%), Gaps = 18/169 (10%)
Query: 80 IELDAKKSPLAL------LAQTCSQIGKPDPPPSSKLNSVAAAANGL--GAEKDPGRSAP 131
IE+ A+K P + L G P PP + AA+ L G E+ PGR AP
Sbjct: 2 IEMAAEKEPFLVPAPPPPLKDESGGGGGPTVPPHQE-----AASGELRGGTERGPGRCAP 56
Query: 132 GAASAAAALKQLGDSPAEDKSSFKPYSKGSGGGDSRKDSGSSSVSS-TSSSSSSSPGDKA 190
A S AAA+ + A SS + GGG + G + +S ++ G++
Sbjct: 57 SAGSPAAAVGRESPGAAATSSSGPQAQQHRGGGPQAQSHGEARLSDPPGRAAPPDVGEER 116
Query: 191 GFRVPSAACPPFPPHGAPVSASSSSSSPGGSRGGSPHHSDCKNGGGVGG 239
+ PP PP P + PGG GG + C GGG GG
Sbjct: 117 RGGGGTELGPPAPPR--PRNGYQPHRPPGG--GGGKRRNSCNVGGGGGG 161
Score = 33.5 bits (75), Expect = 0.56
Identities = 60/258 (23%), Positives = 93/258 (36%), Gaps = 35/258 (13%)
Query: 5 PAGSNPRTPESSGSGSGGGG-KRPAVPAAVSLLPPADPLRQANRL-------PIRVLKML 56
P G + S G GGGG K PA + D + +N L P+ + +L
Sbjct: 142 PGGGGGKRRNSCNVGGGGGGFKHPAFKRRRRVNSDCDSVLPSNFLLGGNIFDPLNLNSLL 201
Query: 57 SAHTGHLLHPEYLQ--PLSSTPVSPIELDAKKS---PLALLAQTCSQIGKPDPPPSSKLN 111
L+ E + PL + P+E+ K PL+L TC+ G +
Sbjct: 202 DEEVSRTLNAETPKSSPLPAKGRDPVEILIPKDITDPLSL--NTCTDEG----------H 249
Query: 112 SVAAAANGLGAEKDPGRSAPGAASAAAALKQLGDSPAEDKSSFKPYSKGSGGGDSRKDSG 171
V A+ G ++ R AA + P + P G G + G
Sbjct: 250 VVLASPLKTGRKRHRHRGQHHQQQQAAGGSE--SHPVPPTAPLTPLLHGEGASQQPRHRG 307
Query: 172 SS--SVSSTSSSSSSSPGDKAGFRVPSAACPPF-----PPHGAPVSASSSSSSPGGSRGG 224
+ + +++ + D+ +PSA P PP + +SA SSSS R
Sbjct: 308 QNRDAPQPYELNTAINCRDEVVSPLPSALQGPSGSLSAPPAASVISAPPSSSSRHRKRRR 367
Query: 225 SPHHSDC-KNGGGVGGGE 241
+ S+ GGG G E
Sbjct: 368 TSSKSEAGARGGGQGSKE 385
>gi|172072684 PR domain containing 1, with ZNF domain isoform 1
[Homo sapiens]
Length = 825
Score = 53.9 bits (128), Expect = 4e-07
Identities = 78/305 (25%), Positives = 107/305 (35%), Gaps = 54/305 (17%)
Query: 201 PFPPHGAPVSASSSSSSPGGSRGGSPHHSDCKNGGGVGGGELDKKDQEPKPSPEPAAVSR 260
P P P S S+ SS + SPH S VG G + +D
Sbjct: 328 PIPSSTTP-SPSARSSPDQSLKSSSPHSSPGNTVSPVGPGSQEHRDSY------------ 374
Query: 261 GGGGEPGAHGGAESGASGRKSEPPSALVGAGHVAPVSPYKPGHSVFPLPPSSIGYHG-SI 319
A+ A G G S P A + A + Y + F LPP + +G S
Sbjct: 375 -------AYLNASYGTEGLGSYPGYAPLPHLPPAFIPSYNAHYPKFLLPPYGMNCNGLSA 427
Query: 320 VGAYAGYPS-QFVPGLDPSKSGLVGGQLSGGLGLPPGKPPSSSPLTGA----SPPSFLQG 374
V + G + P L P S L+GG L P PSS P GA P +
Sbjct: 428 VSSMNGINNFGLFPRLCPVYSNLLGGGSLPHPMLNPTSLPSSLPSDGARRLLQPEHPREV 487
Query: 375 LCRDPYCLGGYHG-ASHLGGSSCSTCSAHDPAGPSLKAGGYPLVYPGHPLQPAALSSSAA 433
L P+ + G A+ + +CS S AG + A H +QP A S++ A
Sbjct: 488 LVPAPHSAFSFTGAAASMKDKACSPTSGSPTAGTAATA--------EHVVQPKATSAAMA 539
Query: 434 QAA-------------LPGHPLYTYGFMLQNEPLPHSCNWVAASGPCDKRFATSEELLSH 480
+ + G+ Y QN + + CN C K F L H
Sbjct: 540 APSSDEAMNLIKNKRNMTGYKTLPYPLKKQNGKIKYECN------VCAKTFGQLSNLKVH 593
Query: 481 LRTHT 485
LR H+
Sbjct: 594 LRVHS 598
>gi|33946274 PR domain containing 1, with ZNF domain isoform 2 [Homo
sapiens]
Length = 691
Score = 53.9 bits (128), Expect = 4e-07
Identities = 78/305 (25%), Positives = 107/305 (35%), Gaps = 54/305 (17%)
Query: 201 PFPPHGAPVSASSSSSSPGGSRGGSPHHSDCKNGGGVGGGELDKKDQEPKPSPEPAAVSR 260
P P P S S+ SS + SPH S VG G + +D
Sbjct: 194 PIPSSTTP-SPSARSSPDQSLKSSSPHSSPGNTVSPVGPGSQEHRDSY------------ 240
Query: 261 GGGGEPGAHGGAESGASGRKSEPPSALVGAGHVAPVSPYKPGHSVFPLPPSSIGYHG-SI 319
A+ A G G S P A + A + Y + F LPP + +G S
Sbjct: 241 -------AYLNASYGTEGLGSYPGYAPLPHLPPAFIPSYNAHYPKFLLPPYGMNCNGLSA 293
Query: 320 VGAYAGYPS-QFVPGLDPSKSGLVGGQLSGGLGLPPGKPPSSSPLTGA----SPPSFLQG 374
V + G + P L P S L+GG L P PSS P GA P +
Sbjct: 294 VSSMNGINNFGLFPRLCPVYSNLLGGGSLPHPMLNPTSLPSSLPSDGARRLLQPEHPREV 353
Query: 375 LCRDPYCLGGYHG-ASHLGGSSCSTCSAHDPAGPSLKAGGYPLVYPGHPLQPAALSSSAA 433
L P+ + G A+ + +CS S AG + A H +QP A S++ A
Sbjct: 354 LVPAPHSAFSFTGAAASMKDKACSPTSGSPTAGTAATA--------EHVVQPKATSAAMA 405
Query: 434 QAA-------------LPGHPLYTYGFMLQNEPLPHSCNWVAASGPCDKRFATSEELLSH 480
+ + G+ Y QN + + CN C K F L H
Sbjct: 406 APSSDEAMNLIKNKRNMTGYKTLPYPLKKQNGKIKYECN------VCAKTFGQLSNLKVH 459
Query: 481 LRTHT 485
LR H+
Sbjct: 460 LRVHS 464
>gi|186928825 dermokine isoform 3 precursor [Homo sapiens]
Length = 416
Score = 53.5 bits (127), Expect = 5e-07
Identities = 47/147 (31%), Positives = 59/147 (40%), Gaps = 25/147 (17%)
Query: 149 EDKSSFKPYSKGSGGGDSRKDSGSSSVSSTSSSSSSSPGDKAGFRVPSAACPPFPPHGAP 208
+++ P GSGGG S +SG S S + SS S S GD +G+
Sbjct: 225 QNEGCTNPPPSGSGGGSS--NSGGGSGSQSGSSGSGSNGDN--------------NNGSS 268
Query: 209 VSASSSSSSPGGSRGGSPHHSDCKNGG--GVGGGELDKKDQEPKPSPEPAAVSRGGGGEP 266
SSS SS GGS GGS S +GG G G E S G G +P
Sbjct: 269 SGGSSSGSSSGGSSGGSSGGSSGNSGGSRGDSGSESSWGSSTGSSSGNHGGSGGGNGHKP 328
Query: 267 G-------AHGGAESGASGRKSEPPSA 286
G A G ESG G + + S+
Sbjct: 329 GCEKPGNEARGSGESGIQGFRGQGVSS 355
Score = 43.1 bits (100), Expect = 7e-04
Identities = 38/141 (26%), Positives = 52/141 (36%), Gaps = 29/141 (20%)
Query: 100 GKPDPPPSSKLNSVAAAANGLGAEKDPGRSAPGAASAAAALKQLGDSPAEDKSSFKPYSK 159
G +PPPS + + G G++ +S + + + + SS S
Sbjct: 228 GCTNPPPSGSGGGSSNSGGGSGSQS--------GSSGSGSNGDNNNGSSSGGSSSGSSSG 279
Query: 160 GSGGGDSRKDSGSSSVSSTSSSSSSSPGDKAGFRVPSAACPPFPPHGAPVSASSSSSSPG 219
GS GG S SG+S S S S SS G G SSS + G
Sbjct: 280 GSSGGSSGGSSGNSGGSRGDSGSESSWGSSTG---------------------SSSGNHG 318
Query: 220 GSRGGSPHHSDCKNGGGVGGG 240
GS GG+ H C+ G G
Sbjct: 319 GSGGGNGHKPGCEKPGNEARG 339
Score = 36.6 bits (83), Expect = 0.066
Identities = 43/199 (21%), Positives = 64/199 (32%), Gaps = 39/199 (19%)
Query: 156 PYSKGSGGGDSRKDSGSSSVSSTSSSSSSSPGDKAGFRVPSAACPPFPPHGAPVSASSSS 215
P+ +G GG + + + S ++ + C PP G+ +S+S
Sbjct: 192 PWGQGGNGGPPNFGTNTQGAVAQPGYGSVRASNQ------NEGCTNPPPSGSGGGSSNSG 245
Query: 216 SSPGGSRG--GSPHHSDCKNGGGVGGGELDKKDQEPKPSPEPAAVSRGGGGEPGAHGGAE 273
G G GS + D NG GG ++ S GG G+ GG+
Sbjct: 246 GGSGSQSGSSGSGSNGDNNNGSSSGGS---------------SSGSSSGGSSGGSSGGSS 290
Query: 274 SGASGRKSEPPSALVGAGHVAPVSPYKPGHSVFPLPPSSIGYHGSIVGAYAGYPSQFVPG 333
+ G + + S SS G HG G P PG
Sbjct: 291 GNSGGSRGDSGSESSWGSSTG----------------SSSGNHGGSGGGNGHKPGCEKPG 334
Query: 334 LDPSKSGLVGGQLSGGLGL 352
+ SG G Q G G+
Sbjct: 335 NEARGSGESGIQGFRGQGV 353
>gi|170650694 centaurin, gamma 1 isoform PIKE-L [Homo sapiens]
Length = 1192
Score = 53.1 bits (126), Expect = 7e-07
Identities = 95/375 (25%), Positives = 127/375 (33%), Gaps = 95/375 (25%)
Query: 85 KKSPLALLAQTCSQIGKPDPPPSSKLNSVAAAANGLGAEK-DPGRSAPGAASAAAALKQL 143
+++ L++ T ++ PPP S + A AA G+E DPG +P A +
Sbjct: 10 RRTTTYLISLTLVKLESVPPPPPSPSAAAAGAAGARGSETGDPG--SPRGAEEPGKKRHE 67
Query: 144 GDSPAEDKSSFKPYSKGSGGGDSRKDSGSSSVSSTSSSSSSSPGDKAGFRVPSAACPPFP 203
+D S G+GG + ++S +S + G R+ A PP P
Sbjct: 68 RLFHRQDALWISTSSAGTGGAEP------PALSPAPASPARPVSPAPGRRLSLWAVPPGP 121
Query: 204 P-----------HGAPVSA--------SSSSSSPGGSRGG------SPHH---------- 228
P GAP S+ S P G GG SPH
Sbjct: 122 PLSGGLSPDPKPGGAPTSSRRPLLSSPSWGGPEPEGRAGGGIPGSSSPHPGTGSRRLKVA 181
Query: 229 --------------SDCKNGGGVGGGE-LDKKDQEPKPSPEPAAVSRGGGGEPGAHGGAE 273
S K GGG G G L + E KP + + S G G A A
Sbjct: 182 PPPPAPKPCKTVTTSGAKAGGGKGAGSRLSWPESEGKPRVKGSKSSAGTGASVSAAATAA 241
Query: 274 SGASGRKSEPPSALVGAGHVA--PVSPYK------------PGHSVFPLPPSSIGYHGS- 318
+ G + S VGAG A +SP K PG PP ++ S
Sbjct: 242 AAGGGGSTASTSGGVGAGAGARGKLSPRKGKSKTLDNSDLHPGPPAGSPPPLTLPPTPSP 301
Query: 319 ---IVGAYAGYPSQFVP-GLDPSKSGLVGGQ---------------LSGGLGLPPGKPPS 359
+ A A P P L+P GL G+ +SG G PP
Sbjct: 302 ATAVTAASAQPPGPAPPITLEPPAPGLKRGREGGRASTRDRKMLKFISGIFTKSTGGPPG 361
Query: 360 SSPLTGASPPSFLQG 374
S PL G PPS G
Sbjct: 362 SGPLPG--PPSLSSG 374
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.309 0.130 0.394
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 33,109,938
Number of Sequences: 37866
Number of extensions: 2197286
Number of successful extensions: 28468
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 249
Number of HSP's successfully gapped in prelim test: 1548
Number of HSP's that attempted gapping in prelim test: 18380
Number of HSP's gapped (non-prelim): 7985
length of query: 590
length of database: 18,247,518
effective HSP length: 108
effective length of query: 482
effective length of database: 14,157,990
effective search space: 6824151180
effective search space used: 6824151180
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.6 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.