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Search of human proteins with 5174517
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|5174517 SMAD family member 7 [Homo sapiens]
(426 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|5174517 SMAD family member 7 [Homo sapiens] 902 0.0
gi|92859871 SMAD family member 6 isoform 1 [Homo sapiens] 374 e-104
gi|218749837 SMAD family member 6 isoform 2 [Homo sapiens] 247 2e-65
gi|209693426 Sma- and Mad-related protein 2 isoform 2 [Homo sapi... 132 6e-31
gi|5174513 mothers against decapentaplegic homolog 3 isoform 1 [... 127 3e-29
gi|51173730 Sma- and Mad-related protein 2 isoform 1 [Homo sapiens] 124 2e-28
gi|5174511 Sma- and Mad-related protein 2 isoform 1 [Homo sapiens] 124 2e-28
gi|5174519 SMAD family member 9 isoform b [Homo sapiens] 119 4e-27
gi|223029442 mothers against decapentaplegic homolog 3 isoform 3... 115 8e-26
gi|187828357 SMAD family member 9 isoform a [Homo sapiens] 100 3e-21
gi|223029440 mothers against decapentaplegic homolog 3 isoform 2... 97 4e-20
gi|51173727 Sma- and Mad-related protein 1 [Homo sapiens] 92 7e-19
gi|5174509 Sma- and Mad-related protein 1 [Homo sapiens] 92 7e-19
gi|47778931 SMAD, mothers against DPP homolog 5 [Homo sapiens] 92 1e-18
gi|47778929 SMAD, mothers against DPP homolog 5 [Homo sapiens] 92 1e-18
gi|47778925 SMAD, mothers against DPP homolog 5 [Homo sapiens] 92 1e-18
gi|223029444 mothers against decapentaplegic homolog 3 isoform 4... 89 1e-17
gi|4885457 mothers against decapentaplegic homolog 4 [Homo sapiens] 88 2e-17
gi|110347449 POU domain, class 4, transcription factor 1 [Homo s... 50 3e-06
gi|52632383 heterogeneous nuclear ribonucleoprotein L isoform a ... 44 4e-04
gi|4503119 cancer/testis antigen 1B [Homo sapiens] 42 0.001
gi|21281685 cancer/testis antigen 1A [Homo sapiens] 42 0.001
gi|24586686 voltage-dependent calcium channel gamma-8 subunit [H... 42 0.001
gi|4507163 SRY (sex determining region Y)-box 4 [Homo sapiens] 42 0.001
gi|109452587 family with sequence similarity 98, member B isofor... 42 0.001
gi|23510368 homeobox D11 [Homo sapiens] 41 0.002
gi|25777671 protein phosphatase 1, regulatory subunit 10 [Homo s... 41 0.002
gi|18375613 dachshund homolog 1 isoform b [Homo sapiens] 41 0.002
gi|18375611 dachshund homolog 1 isoform a [Homo sapiens] 41 0.002
gi|18375609 dachshund homolog 1 isoform c [Homo sapiens] 41 0.002
>gi|5174517 SMAD family member 7 [Homo sapiens]
Length = 426
Score = 902 bits (2332), Expect = 0.0
Identities = 426/426 (100%), Positives = 426/426 (100%)
Query: 1 MFRTKRSALVRRLWRSRAPGGEDEEEGAGGGGGGGELRGEGATDSRAHGAGGGGPGRAGC 60
MFRTKRSALVRRLWRSRAPGGEDEEEGAGGGGGGGELRGEGATDSRAHGAGGGGPGRAGC
Sbjct: 1 MFRTKRSALVRRLWRSRAPGGEDEEEGAGGGGGGGELRGEGATDSRAHGAGGGGPGRAGC 60
Query: 61 CLGKAVRGAKGHHHPHPPAAGAGAAGGAEADLKALTHSVLKKLKERQLELLLQAVESRGG 120
CLGKAVRGAKGHHHPHPPAAGAGAAGGAEADLKALTHSVLKKLKERQLELLLQAVESRGG
Sbjct: 61 CLGKAVRGAKGHHHPHPPAAGAGAAGGAEADLKALTHSVLKKLKERQLELLLQAVESRGG 120
Query: 121 TRTACLLLPGRLDCRLGPGAPAGAQPAQPPSSYSLPLLLCKVFRWPDLRHSSEVKRLCCC 180
TRTACLLLPGRLDCRLGPGAPAGAQPAQPPSSYSLPLLLCKVFRWPDLRHSSEVKRLCCC
Sbjct: 121 TRTACLLLPGRLDCRLGPGAPAGAQPAQPPSSYSLPLLLCKVFRWPDLRHSSEVKRLCCC 180
Query: 181 ESYGKINPELVCCNPHHLSRLCELESPPPPYSRYPMDFLKPTADCPDAVPSSAETGGTNY 240
ESYGKINPELVCCNPHHLSRLCELESPPPPYSRYPMDFLKPTADCPDAVPSSAETGGTNY
Sbjct: 181 ESYGKINPELVCCNPHHLSRLCELESPPPPYSRYPMDFLKPTADCPDAVPSSAETGGTNY 240
Query: 241 LAPGGLSDSQLLLEPGDRSHWCVVAYWEEKTRVGRLYCVQEPSLDIFYDLPQGNGFCLGQ 300
LAPGGLSDSQLLLEPGDRSHWCVVAYWEEKTRVGRLYCVQEPSLDIFYDLPQGNGFCLGQ
Sbjct: 241 LAPGGLSDSQLLLEPGDRSHWCVVAYWEEKTRVGRLYCVQEPSLDIFYDLPQGNGFCLGQ 300
Query: 301 LNSDNKSQLVQKVRSKIGCGIQLTREVDGVWVYNRSSYPIFIKSATLDNPDSRTLLVHKV 360
LNSDNKSQLVQKVRSKIGCGIQLTREVDGVWVYNRSSYPIFIKSATLDNPDSRTLLVHKV
Sbjct: 301 LNSDNKSQLVQKVRSKIGCGIQLTREVDGVWVYNRSSYPIFIKSATLDNPDSRTLLVHKV 360
Query: 361 FPGFSIKAFDYEKAYSLQRPNDHEFMQQPWTGFTVQISFVKGWGQCYTRQFISSCPCWLE 420
FPGFSIKAFDYEKAYSLQRPNDHEFMQQPWTGFTVQISFVKGWGQCYTRQFISSCPCWLE
Sbjct: 361 FPGFSIKAFDYEKAYSLQRPNDHEFMQQPWTGFTVQISFVKGWGQCYTRQFISSCPCWLE 420
Query: 421 VIFNSR 426
VIFNSR
Sbjct: 421 VIFNSR 426
>gi|92859871 SMAD family member 6 isoform 1 [Homo sapiens]
Length = 496
Score = 374 bits (960), Expect = e-104
Identities = 229/509 (44%), Positives = 282/509 (55%), Gaps = 99/509 (19%)
Query: 1 MFRTKRSALVRRLWRSRA-PGGEDEEEGAGGGG------------------GGG----EL 37
MFR+KRS LVRRLWRSR P E+ G GGGG GGG E+
Sbjct: 1 MFRSKRSGLVRRLWRSRVVPDREEGGSGGGGGGDEDGSLGSRAEPAPRAREGGGCGRSEV 60
Query: 38 R-----------------------------------GEGATDSRAHGAGGGGPG------ 56
R G GA S A GGPG
Sbjct: 61 RPVAPRRPRDAVGQRGAQGAGRRRRAGGPPRPMSEPGAGAGSSLLDVAEPGGPGWLPESD 120
Query: 57 --RAGCCLGKAVRGAKGHHHPHPPAAGAGA--AGGA------------EADLKALTHSVL 100
CCL A P AGA AGG E +LK +T+S+L
Sbjct: 121 CETVTCCLFSERDAAGAPRDASDPLAGAALEPAGGGRSREARSRLLLLEQELKTVTYSLL 180
Query: 101 KKLKERQLELLLQAVESRGGTRTACLLLPGRLDCRLGPGAPAGAQPAQPPSSYSLPLLLC 160
K+LKER L+ LL+AVESRGG C+L+P R D RLG QPA P LLL
Sbjct: 181 KRLKERSLDTLLEAVESRGGVPGGCVLVP-RADLRLG------GQPAPPQ------LLLG 227
Query: 161 KVFRWPDLRHSSEVKRLCCCESYGKI-NPELVCCNPHHLSRLCELESPPPPYSRY-PMDF 218
++FRWPDL+H+ E+K LC C S+ + VCCNP+H SRLC ESPPPPYSR P D
Sbjct: 228 RLFRWPDLQHAVELKPLCGCHSFAAAADGPTVCCNPYHFSRLCGPESPPPPYSRLSPRDE 287
Query: 219 LKPTADCPDAVPSSAETGGTNYL--APGGLSDSQLLLEPGDRSHWCVVAYWEEKTRVGRL 276
KP D D+ S ET TN L APG SD+ + + SHWC VAYWE +TRVGRL
Sbjct: 288 YKPL-DLSDSTLSYTETEATNSLITAPGEFSDASMSPDATKPSHWCSVAYWEHRTRVGRL 346
Query: 277 YCVQEPSLDIFYDLPQGNGFCLGQLNSDNKSQLVQKVRSKIGCGIQLTREVDGVWVYNRS 336
Y V + ++ IFYDLPQG+GFCLGQLN + +S+ V++ RSKIG GI L++E DGVW YNR
Sbjct: 347 YAVYDQAVSIFYDLPQGSGFCLGQLNLEQRSESVRRTRSKIGFGILLSKEPDGVWAYNRG 406
Query: 337 SYPIFIKSATLDNPDSRTLLVHKVFPGFSIKAFDYEKAYSLQRPNDHEFMQQPWTGFTVQ 396
+PIF+ S TLD P R L+V KV PG+SIK FD+E++ LQ + + P+ +V+
Sbjct: 407 EHPIFVNSPTLDAPGGRALVVRKVPPGYSIKVFDFERS-GLQHAPEPDAADGPYDPNSVR 465
Query: 397 ISFVKGWGQCYTRQFISSCPCWLEVIFNS 425
ISF KGWG CY+RQFI+SCPCWLE++ N+
Sbjct: 466 ISFAKGWGPCYSRQFITSCPCWLEILLNN 494
>gi|218749837 SMAD family member 6 isoform 2 [Homo sapiens]
Length = 235
Score = 247 bits (630), Expect = 2e-65
Identities = 122/224 (54%), Positives = 156/224 (69%), Gaps = 5/224 (2%)
Query: 205 ESPPPPYSRY-PMDFLKPTADCPDAVPSSAETGGTNYL--APGGLSDSQLLLEPGDRSHW 261
+SPPPPYSR P D KP D D+ S ET TN L APG SD+ + + SHW
Sbjct: 12 KSPPPPYSRLSPRDEYKPL-DLSDSTLSYTETEATNSLITAPGEFSDASMSPDATKPSHW 70
Query: 262 CVVAYWEEKTRVGRLYCVQEPSLDIFYDLPQGNGFCLGQLNSDNKSQLVQKVRSKIGCGI 321
C VAYWE +TRVGRLY V + ++ IFYDLPQG+GFCLGQLN + +S+ V++ RSKIG GI
Sbjct: 71 CSVAYWEHRTRVGRLYAVYDQAVSIFYDLPQGSGFCLGQLNLEQRSESVRRTRSKIGFGI 130
Query: 322 QLTREVDGVWVYNRSSYPIFIKSATLDNPDSRTLLVHKVFPGFSIKAFDYEKAYSLQRPN 381
L++E DGVW YNR +PIF+ S TLD P R L+V KV PG+SIK FD+E++ LQ
Sbjct: 131 LLSKEPDGVWAYNRGEHPIFVNSPTLDAPGGRALVVRKVPPGYSIKVFDFERS-GLQHAP 189
Query: 382 DHEFMQQPWTGFTVQISFVKGWGQCYTRQFISSCPCWLEVIFNS 425
+ + P+ +V+ISF KGWG CY+RQFI+SCPCWLE++ N+
Sbjct: 190 EPDAADGPYDPNSVRISFAKGWGPCYSRQFITSCPCWLEILLNN 233
>gi|209693426 Sma- and Mad-related protein 2 isoform 2 [Homo
sapiens]
Length = 437
Score = 132 bits (332), Expect = 6e-31
Identities = 117/404 (28%), Positives = 182/404 (45%), Gaps = 70/404 (17%)
Query: 79 AAGAGAAGGAEAD------LKALTHSVLKKLKER-QLELLLQAVESRGGTRTACLLLPGR 131
A G+G AGG E + + S++KKLK+ +L+ L +A+ ++ T C+ +P
Sbjct: 22 AGGSGGAGGGEQNGQEEKWCEKAVKSLVKKLKKTGRLDELEKAITTQN-CNTKCVTIPRS 80
Query: 132 LDCRLGPGAPAGAQPAQPPSSYSLP-LLLCKVFRWPDLRHSSEVKRLCCCESYGKINPEL 190
LD RL Q LP ++ C+++RWPDL E+K + CE + +
Sbjct: 81 LDGRL-----------QVSHRKGLPHVIYCRLWRWPDLHSHHELKAIENCEYAFNLKKDE 129
Query: 191 VCCNPHHLSRLCELESPP-------------PPYSRY----------------------- 214
VC NP+H R+ PP PP Y
Sbjct: 130 VCVNPYHYQRVETPVLPPVLVPRHTEILTELPPLDDYTHSIPENTNFPAGIEPQSNYIPE 189
Query: 215 --PMDFLKPTADCPD-AVPSSAETGGTNYLAPGGLS--DSQLLLEP---GDRSHWCVVAY 266
P ++ + D + S +TG L+P LS + L L+P + + WC +AY
Sbjct: 190 TPPPGYISEDGETSDQQLNQSMDTGSPAELSPTTLSPVNHSLDLQPVTYSEPAFWCSIAY 249
Query: 267 WEEKTRVGRLYCVQEPSL--DIFYDLPQGNGFCLGQLNSDNKSQLVQKVRSKIGCGIQLT 324
+E RVG + +PSL D F D FCLG L++ N++ V+ R IG G++L
Sbjct: 250 YELNQRVGETFHASQPSLTVDGFTDPSNSERFCLGLLSNVNRNATVEMTRRHIGRGVRLY 309
Query: 325 REVDGVWVYNRSSYPIFIKSATLDNPDS-RTLLVHKVFPGFSIKAFDYEKAYSL--QRPN 381
V+ S IF++S + V K+ PG ++K F+ ++ +L Q N
Sbjct: 310 YIGGEVFAECLSDSAIFVQSPNCNQRYGWHPATVCKIPPGCNLKIFNNQEFAALLAQSVN 369
Query: 382 D-HEFMQQPWTGFTVQISFVKGWGQCYTRQFISSCPCWLEVIFN 424
E + Q T+++SFVKGWG Y RQ ++S PCW+E+ N
Sbjct: 370 QGFEAVYQLTRMCTIRMSFVKGWGAEYRRQTVTSTPCWIELHLN 413
>gi|5174513 mothers against decapentaplegic homolog 3 isoform 1
[Homo sapiens]
Length = 425
Score = 127 bits (318), Expect = 3e-29
Identities = 107/377 (28%), Positives = 178/377 (47%), Gaps = 62/377 (16%)
Query: 98 SVLKKLKER-QLELLLQAVESRGGTRTACLLLPGRLDCRLGPGAPAGAQPAQPPSSYSLP 156
S++KKLK+ QL+ L +A+ ++ T C+ +P LD RL Q LP
Sbjct: 37 SLVKKLKKTGQLDELEKAITTQN-VNTKCITIPRSLDGRL-----------QVSHRKGLP 84
Query: 157 -LLLCKVFRWPDLRHSSEVKRLCCCESYGKINPELVCCNPHHLSRLCELESPP---PPYS 212
++ C+++RWPDL E++ + CE + + VC NP+H R+ PP P ++
Sbjct: 85 HVIYCRLWRWPDLHSHHELRAMELCEFAFNMKKDEVCVNPYHYQRVETPVLPPVLVPRHT 144
Query: 213 RYPMDF-------------------LKPTADCPDAVPSS--AETG-------------GT 238
P +F ++P ++ P+ P +E G G+
Sbjct: 145 EIPAEFPPLDDYSHSIPENTNFPAGIEPQSNIPETPPPGYLSEDGETSDHQMNHSMDAGS 204
Query: 239 NYLAPGGLSDSQ--LLLEPG---DRSHWCVVAYWEEKTRVGRLYCVQEPSLDI--FYDLP 291
L+P +S + L L+P + + WC ++Y+E RVG + +PS+ + F D
Sbjct: 205 PNLSPNPMSPAHNNLDLQPVTYCEPAFWCSISYYELNQRVGETFHASQPSMTVDGFTDPS 264
Query: 292 QGNGFCLGQLNSDNKSQLVQKVRSKIGCGIQLTREVDGVWVYNRSSYPIFIKSATLDNPD 351
FCLG L++ N++ V+ R IG G++L V+ S IF++S +
Sbjct: 265 NSERFCLGLLSNVNRNAAVELTRRHIGRGVRLYYIGGEVFAECLSDSAIFVQSPNCNQRY 324
Query: 352 S-RTLLVHKVFPGFSIKAFDYEKAYSL--QRPND-HEFMQQPWTGFTVQISFVKGWGQCY 407
V K+ PG ++K F+ ++ +L Q N E + Q T+++SFVKGWG Y
Sbjct: 325 GWHPATVCKIPPGCNLKIFNNQEFAALLAQSVNQGFEAVYQLTRMCTIRMSFVKGWGAEY 384
Query: 408 TRQFISSCPCWLEVIFN 424
RQ ++S PCW+E+ N
Sbjct: 385 RRQTVTSTPCWIELHLN 401
>gi|51173730 Sma- and Mad-related protein 2 isoform 1 [Homo sapiens]
Length = 467
Score = 124 bits (310), Expect = 2e-28
Identities = 116/423 (27%), Positives = 181/423 (42%), Gaps = 78/423 (18%)
Query: 79 AAGAGAAGGAEAD------LKALTHSVLKKLKER-QLELLLQAVESRGGTRTACLLLPGR 131
A G+G AGG E + + S++KKLK+ +L+ L +A+ ++ T C+ +P
Sbjct: 22 AGGSGGAGGGEQNGQEEKWCEKAVKSLVKKLKKTGRLDELEKAITTQN-CNTKCVTIPST 80
Query: 132 LDCRLGPGAPAGAQPAQPPSSYS-------------------LP-LLLCKVFRWPDLRHS 171
G P YS LP ++ C+++RWPDL
Sbjct: 81 CSEIWGLSTPNTIDQWDTTGLYSFSEQTRSLDGRLQVSHRKGLPHVIYCRLWRWPDLHSH 140
Query: 172 SEVKRLCCCESYGKINPELVCCNPHHLSRLCELESPP-------------PPYSRY---- 214
E+K + CE + + VC NP+H R+ PP PP Y
Sbjct: 141 HELKAIENCEYAFNLKKDEVCVNPYHYQRVETPVLPPVLVPRHTEILTELPPLDDYTHSI 200
Query: 215 ---------------------PMDFLKPTADCPD-AVPSSAETGGTNYLAPGGLS--DSQ 250
P ++ + D + S +TG L+P LS +
Sbjct: 201 PENTNFPAGIEPQSNYIPETPPPGYISEDGETSDQQLNQSMDTGSPAELSPTTLSPVNHS 260
Query: 251 LLLEP---GDRSHWCVVAYWEEKTRVGRLYCVQEPSL--DIFYDLPQGNGFCLGQLNSDN 305
L L+P + + WC +AY+E RVG + +PSL D F D FCLG L++ N
Sbjct: 261 LDLQPVTYSEPAFWCSIAYYELNQRVGETFHASQPSLTVDGFTDPSNSERFCLGLLSNVN 320
Query: 306 KSQLVQKVRSKIGCGIQLTREVDGVWVYNRSSYPIFIKSATLDNPDS-RTLLVHKVFPGF 364
++ V+ R IG G++L V+ S IF++S + V K+ PG
Sbjct: 321 RNATVEMTRRHIGRGVRLYYIGGEVFAECLSDSAIFVQSPNCNQRYGWHPATVCKIPPGC 380
Query: 365 SIKAFDYEKAYSL--QRPND-HEFMQQPWTGFTVQISFVKGWGQCYTRQFISSCPCWLEV 421
++K F+ ++ +L Q N E + Q T+++SFVKGWG Y RQ ++S PCW+E+
Sbjct: 381 NLKIFNNQEFAALLAQSVNQGFEAVYQLTRMCTIRMSFVKGWGAEYRRQTVTSTPCWIEL 440
Query: 422 IFN 424
N
Sbjct: 441 HLN 443
>gi|5174511 Sma- and Mad-related protein 2 isoform 1 [Homo sapiens]
Length = 467
Score = 124 bits (310), Expect = 2e-28
Identities = 116/423 (27%), Positives = 181/423 (42%), Gaps = 78/423 (18%)
Query: 79 AAGAGAAGGAEAD------LKALTHSVLKKLKER-QLELLLQAVESRGGTRTACLLLPGR 131
A G+G AGG E + + S++KKLK+ +L+ L +A+ ++ T C+ +P
Sbjct: 22 AGGSGGAGGGEQNGQEEKWCEKAVKSLVKKLKKTGRLDELEKAITTQN-CNTKCVTIPST 80
Query: 132 LDCRLGPGAPAGAQPAQPPSSYS-------------------LP-LLLCKVFRWPDLRHS 171
G P YS LP ++ C+++RWPDL
Sbjct: 81 CSEIWGLSTPNTIDQWDTTGLYSFSEQTRSLDGRLQVSHRKGLPHVIYCRLWRWPDLHSH 140
Query: 172 SEVKRLCCCESYGKINPELVCCNPHHLSRLCELESPP-------------PPYSRY---- 214
E+K + CE + + VC NP+H R+ PP PP Y
Sbjct: 141 HELKAIENCEYAFNLKKDEVCVNPYHYQRVETPVLPPVLVPRHTEILTELPPLDDYTHSI 200
Query: 215 ---------------------PMDFLKPTADCPD-AVPSSAETGGTNYLAPGGLS--DSQ 250
P ++ + D + S +TG L+P LS +
Sbjct: 201 PENTNFPAGIEPQSNYIPETPPPGYISEDGETSDQQLNQSMDTGSPAELSPTTLSPVNHS 260
Query: 251 LLLEP---GDRSHWCVVAYWEEKTRVGRLYCVQEPSL--DIFYDLPQGNGFCLGQLNSDN 305
L L+P + + WC +AY+E RVG + +PSL D F D FCLG L++ N
Sbjct: 261 LDLQPVTYSEPAFWCSIAYYELNQRVGETFHASQPSLTVDGFTDPSNSERFCLGLLSNVN 320
Query: 306 KSQLVQKVRSKIGCGIQLTREVDGVWVYNRSSYPIFIKSATLDNPDS-RTLLVHKVFPGF 364
++ V+ R IG G++L V+ S IF++S + V K+ PG
Sbjct: 321 RNATVEMTRRHIGRGVRLYYIGGEVFAECLSDSAIFVQSPNCNQRYGWHPATVCKIPPGC 380
Query: 365 SIKAFDYEKAYSL--QRPND-HEFMQQPWTGFTVQISFVKGWGQCYTRQFISSCPCWLEV 421
++K F+ ++ +L Q N E + Q T+++SFVKGWG Y RQ ++S PCW+E+
Sbjct: 381 NLKIFNNQEFAALLAQSVNQGFEAVYQLTRMCTIRMSFVKGWGAEYRRQTVTSTPCWIEL 440
Query: 422 IFN 424
N
Sbjct: 441 HLN 443
>gi|5174519 SMAD family member 9 isoform b [Homo sapiens]
Length = 430
Score = 119 bits (299), Expect = 4e-27
Identities = 108/375 (28%), Positives = 163/375 (43%), Gaps = 62/375 (16%)
Query: 98 SVLKKLKERQLEL-LLQAVESRGGTRTACLLLPGRLDCRLGPGAPAGAQPAQPPSSYSLP 156
S++KKLK+++ + L+ S G + C+ +P LD RL Q LP
Sbjct: 40 SLVKKLKKKKGAMDELERALSCPGQPSKCVTIPRSLDGRL-----------QVSHRKGLP 88
Query: 157 -LLLCKVFRWPDLRHSSEVKRLCCCESYGKINPELVCCNPHHLSRL-------------- 201
++ C+V+RWPDL+ E+K L CCE + VC NP+H R+
Sbjct: 89 HVIYCRVWRWPDLQSHHELKPLECCEFPFGSKQKEVCINPYHYRRVETPVLPPVLVPRHS 148
Query: 202 --------------CELESPP--PPYSRYPMDFLKPTADCPDAVPSSAETGG---TNYL- 241
L S P P + YP F +P PS A + +Y
Sbjct: 149 EYNPQLSLLAKFRSASLHSEPLMPHNATYPDSFQQPPCSALPPSPSHAFSQSPCTASYPH 208
Query: 242 APGGLSDSQLLLEPGD--------RSHWCVVAYWEEKTRVGRLYCVQEPS--LDIFYDLP 291
+PG S+ + + D HWC VAY+E RVG + S +D F D
Sbjct: 209 SPGSPSEPESPYQHSDFRPVCYEEPQHWCSVAYYELNNRVGETFQASSRSVLIDGFTDPS 268
Query: 292 QG-NGFCLGQLNSDNKSQLVQKVRSKIGCGIQLTREVDGVWVYNRSSYPIFIKSATLDNP 350
N FCLG L++ N++ ++ R IG G+ L V+ S IF++S +
Sbjct: 269 NNRNRFCLGLLSNVNRNSTIENTRRHIGKGVHLYYVGGEVYAECVSDSSIFVQSRNCNYQ 328
Query: 351 DS-RTLLVHKVFPGFSIKAFDYEKAYSLQRPNDH---EFMQQPWTGFTVQISFVKGWGQC 406
V K+ G S+K F+ + L + H E + + T+++SFVKGWG
Sbjct: 329 HGFHPATVCKIPSGCSLKVFNNQLFAQLLAQSVHHGFEVVYELTKMCTIRMSFVKGWGAE 388
Query: 407 YTRQFISSCPCWLEV 421
Y RQ ++S PCW+E+
Sbjct: 389 YHRQDVTSTPCWIEI 403
>gi|223029442 mothers against decapentaplegic homolog 3 isoform 3
[Homo sapiens]
Length = 381
Score = 115 bits (288), Expect = 8e-26
Identities = 88/316 (27%), Positives = 149/316 (47%), Gaps = 48/316 (15%)
Query: 157 LLLCKVFRWPDLRHSSEVKRLCCCESYGKINPELVCCNPHHLSRLCELESPP---PPYSR 213
++ C+++RWPDL E++ + CE + + VC NP+H R+ PP P ++
Sbjct: 42 VIYCRLWRWPDLHSHHELRAMELCEFAFNMKKDEVCVNPYHYQRVETPVLPPVLVPRHTE 101
Query: 214 YPMDF-------------------LKPTADCPDAVPSS--AETG-------------GTN 239
P +F ++P ++ P+ P +E G G+
Sbjct: 102 IPAEFPPLDDYSHSIPENTNFPAGIEPQSNIPETPPPGYLSEDGETSDHQMNHSMDAGSP 161
Query: 240 YLAPGGLSDSQ--LLLEPG---DRSHWCVVAYWEEKTRVGRLYCVQEPSLDI--FYDLPQ 292
L+P +S + L L+P + + WC ++Y+E RVG + +PS+ + F D
Sbjct: 162 NLSPNPMSPAHNNLDLQPVTYCEPAFWCSISYYELNQRVGETFHASQPSMTVDGFTDPSN 221
Query: 293 GNGFCLGQLNSDNKSQLVQKVRSKIGCGIQLTREVDGVWVYNRSSYPIFIKSATLDNPDS 352
FCLG L++ N++ V+ R IG G++L V+ S IF++S +
Sbjct: 222 SERFCLGLLSNVNRNAAVELTRRHIGRGVRLYYIGGEVFAECLSDSAIFVQSPNCNQRYG 281
Query: 353 -RTLLVHKVFPGFSIKAFDYEKAYSL--QRPND-HEFMQQPWTGFTVQISFVKGWGQCYT 408
V K+ PG ++K F+ ++ +L Q N E + Q T+++SFVKGWG Y
Sbjct: 282 WHPATVCKIPPGCNLKIFNNQEFAALLAQSVNQGFEAVYQLTRMCTIRMSFVKGWGAEYR 341
Query: 409 RQFISSCPCWLEVIFN 424
RQ ++S PCW+E+ N
Sbjct: 342 RQTVTSTPCWIELHLN 357
>gi|187828357 SMAD family member 9 isoform a [Homo sapiens]
Length = 467
Score = 100 bits (248), Expect = 3e-21
Identities = 110/412 (26%), Positives = 163/412 (39%), Gaps = 99/412 (24%)
Query: 98 SVLKKLKERQLEL-LLQAVESRGGTRTACLLLPGRLDCRLGPGAPAGAQPAQPPSSYSLP 156
S++KKLK+++ + L+ S G + C+ +P LD RL Q LP
Sbjct: 40 SLVKKLKKKKGAMDELERALSCPGQPSKCVTIPRSLDGRL-----------QVSHRKGLP 88
Query: 157 -LLLCKVFRWPDLRHSSEVKRLCCCESYGKINPELVCCN-----------------PHHL 198
++ C+V+RWPDL+ E+K L CCE + VC N P H
Sbjct: 89 HVIYCRVWRWPDLQSHHELKPLECCEFPFGSKQKEVCINPYHYRRVETPVLPPVLVPRHS 148
Query: 199 S-----------RLCELESPP--PPYSRYPMDFLKPTADCPDAVPSSAETGG---TNYL- 241
R L S P P + YP F +P PS A + +Y
Sbjct: 149 EYNPQLSLLAKFRSASLHSEPLMPHNATYPDSFQQPPCSALPPSPSHAFSQSPCTASYPH 208
Query: 242 APGGLSDSQ-------------------------------------LLLEPGD------- 257
+PG S+ + L + GD
Sbjct: 209 SPGSPSEPESPYQHSVDTPPLPYHATEASETQSGQPVDATADRHVVLSIPNGDFRPVCYE 268
Query: 258 -RSHWCVVAYWEEKTRVGRLYCVQEPS--LDIFYDLPQG-NGFCLGQLNSDNKSQLVQKV 313
HWC VAY+E RVG + S +D F D N FCLG L++ N++ ++
Sbjct: 269 EPQHWCSVAYYELNNRVGETFQASSRSVLIDGFTDPSNNRNRFCLGLLSNVNRNSTIENT 328
Query: 314 RSKIGCGIQLTREVDGVWVYNRSSYPIFIKSATLDNPDS-RTLLVHKVFPGFSIKAFDYE 372
R IG G+ L V+ S IF++S + V K+ G S+K F+ +
Sbjct: 329 RRHIGKGVHLYYVGGEVYAECVSDSSIFVQSRNCNYQHGFHPATVCKIPSGCSLKVFNNQ 388
Query: 373 KAYSLQRPNDH---EFMQQPWTGFTVQISFVKGWGQCYTRQFISSCPCWLEV 421
L + H E + + T+++SFVKGWG Y RQ ++S PCW+E+
Sbjct: 389 LFAQLLAQSVHHGFEVVYELTKMCTIRMSFVKGWGAEYHRQDVTSTPCWIEI 440
>gi|223029440 mothers against decapentaplegic homolog 3 isoform 2
[Homo sapiens]
Length = 320
Score = 96.7 bits (239), Expect = 4e-20
Identities = 81/293 (27%), Positives = 134/293 (45%), Gaps = 48/293 (16%)
Query: 180 CESYGKINPELVCCNPHHLSRLCELESPP---PPYSRYPMDF------------------ 218
CE + + VC NP+H R+ PP P ++ P +F
Sbjct: 4 CEFAFNMKKDEVCVNPYHYQRVETPVLPPVLVPRHTEIPAEFPPLDDYSHSIPENTNFPA 63
Query: 219 -LKPTADCPDAVPSS--AETG-------------GTNYLAPGGLSDSQ--LLLEPG---D 257
++P ++ P+ P +E G G+ L+P +S + L L+P +
Sbjct: 64 GIEPQSNIPETPPPGYLSEDGETSDHQMNHSMDAGSPNLSPNPMSPAHNNLDLQPVTYCE 123
Query: 258 RSHWCVVAYWEEKTRVGRLYCVQEPSLDI--FYDLPQGNGFCLGQLNSDNKSQLVQKVRS 315
+ WC ++Y+E RVG + +PS+ + F D FCLG L++ N++ V+ R
Sbjct: 124 PAFWCSISYYELNQRVGETFHASQPSMTVDGFTDPSNSERFCLGLLSNVNRNAAVELTRR 183
Query: 316 KIGCGIQLTREVDGVWVYNRSSYPIFIKSATLDNPDS-RTLLVHKVFPGFSIKAFDYEKA 374
IG G++L V+ S IF++S + V K+ PG ++K F+ ++
Sbjct: 184 HIGRGVRLYYIGGEVFAECLSDSAIFVQSPNCNQRYGWHPATVCKIPPGCNLKIFNNQEF 243
Query: 375 YSL--QRPND-HEFMQQPWTGFTVQISFVKGWGQCYTRQFISSCPCWLEVIFN 424
+L Q N E + Q T+++SFVKGWG Y RQ ++S PCW+E+ N
Sbjct: 244 AALLAQSVNQGFEAVYQLTRMCTIRMSFVKGWGAEYRRQTVTSTPCWIELHLN 296
>gi|51173727 Sma- and Mad-related protein 1 [Homo sapiens]
Length = 465
Score = 92.4 bits (228), Expect = 7e-19
Identities = 111/417 (26%), Positives = 171/417 (41%), Gaps = 107/417 (25%)
Query: 98 SVLKKLKERQ--LELLLQAVESRGGTRTACLLLPGRLDCRLGPGAPAGAQPAQPPSSYSL 155
+++KKLK+++ +E L +A+ S G + C+ +P LD RL Q L
Sbjct: 36 ALVKKLKKKKGAMEELEKAL-SCPGQPSNCVTIPRSLDGRL-----------QVSHRKGL 83
Query: 156 P-LLLCKVFRWPDLRHSSEVKRL-CCCESYGKINPELVCC-------------------- 193
P ++ C+V+RWPDL+ E+K L CC +G E VC
Sbjct: 84 PHVIYCRVWRWPDLQSHHELKPLECCEFPFGSKQKE-VCINPYHYKRVESPVLPPVLVPR 142
Query: 194 ----NPHHLSRLCELES--------------------------PPPPYSRYPMDFLKPTA 223
NP H S L + + P P S YP ++
Sbjct: 143 HSEYNPQH-SLLAQFRNLGQNEPHMPLNATFPDSFQQPNSHPFPHSPNSSYPNSPGSSSS 201
Query: 224 DCPDAVPSS---------AETGGTNYLAP--------GGLSDSQLLLEP-------GD-- 257
P + SS A+T YL P D+ ++ P GD
Sbjct: 202 TYPHSPTSSDPGSPFQMPADTPPPAYLPPEDPMTQDGSQPMDTNMMAPPLPSEINRGDVQ 261
Query: 258 ------RSHWCVVAYWEEKTRVGRLYCVQEPSL--DIFYDLPQG-NGFCLGQLNSDNKSQ 308
HWC + Y+E RVG + S+ D F D N FCLG L++ N++
Sbjct: 262 AVAYEEPKHWCSIVYYELNNRVGEAFHASSTSVLVDGFTDPSNNKNRFCLGLLSNVNRNS 321
Query: 309 LVQKVRSKIGCGIQLTREVDGVWVYNRSSYPIFIKSATLD-NPDSRTLLVHKVFPGFSIK 367
++ R IG G+ L V+ S IF++S + + V K+ G S+K
Sbjct: 322 TIENTRRHIGKGVHLYYVGGEVYAECLSDSSIFVQSRNCNYHHGFHPTTVCKIPSGCSLK 381
Query: 368 AFDYEK-AYSLQRPNDHEF--MQQPWTGFTVQISFVKGWGQCYTRQFISSCPCWLEV 421
F+ ++ A L + +H F + + T+++SFVKGWG Y RQ ++S PCW+E+
Sbjct: 382 IFNNQEFAQLLAQSVNHGFETVYELTKMCTIRMSFVKGWGAEYHRQDVTSTPCWIEI 438
>gi|5174509 Sma- and Mad-related protein 1 [Homo sapiens]
Length = 465
Score = 92.4 bits (228), Expect = 7e-19
Identities = 111/417 (26%), Positives = 171/417 (41%), Gaps = 107/417 (25%)
Query: 98 SVLKKLKERQ--LELLLQAVESRGGTRTACLLLPGRLDCRLGPGAPAGAQPAQPPSSYSL 155
+++KKLK+++ +E L +A+ S G + C+ +P LD RL Q L
Sbjct: 36 ALVKKLKKKKGAMEELEKAL-SCPGQPSNCVTIPRSLDGRL-----------QVSHRKGL 83
Query: 156 P-LLLCKVFRWPDLRHSSEVKRL-CCCESYGKINPELVCC-------------------- 193
P ++ C+V+RWPDL+ E+K L CC +G E VC
Sbjct: 84 PHVIYCRVWRWPDLQSHHELKPLECCEFPFGSKQKE-VCINPYHYKRVESPVLPPVLVPR 142
Query: 194 ----NPHHLSRLCELES--------------------------PPPPYSRYPMDFLKPTA 223
NP H S L + + P P S YP ++
Sbjct: 143 HSEYNPQH-SLLAQFRNLGQNEPHMPLNATFPDSFQQPNSHPFPHSPNSSYPNSPGSSSS 201
Query: 224 DCPDAVPSS---------AETGGTNYLAP--------GGLSDSQLLLEP-------GD-- 257
P + SS A+T YL P D+ ++ P GD
Sbjct: 202 TYPHSPTSSDPGSPFQMPADTPPPAYLPPEDPMTQDGSQPMDTNMMAPPLPSEINRGDVQ 261
Query: 258 ------RSHWCVVAYWEEKTRVGRLYCVQEPSL--DIFYDLPQG-NGFCLGQLNSDNKSQ 308
HWC + Y+E RVG + S+ D F D N FCLG L++ N++
Sbjct: 262 AVAYEEPKHWCSIVYYELNNRVGEAFHASSTSVLVDGFTDPSNNKNRFCLGLLSNVNRNS 321
Query: 309 LVQKVRSKIGCGIQLTREVDGVWVYNRSSYPIFIKSATLD-NPDSRTLLVHKVFPGFSIK 367
++ R IG G+ L V+ S IF++S + + V K+ G S+K
Sbjct: 322 TIENTRRHIGKGVHLYYVGGEVYAECLSDSSIFVQSRNCNYHHGFHPTTVCKIPSGCSLK 381
Query: 368 AFDYEK-AYSLQRPNDHEF--MQQPWTGFTVQISFVKGWGQCYTRQFISSCPCWLEV 421
F+ ++ A L + +H F + + T+++SFVKGWG Y RQ ++S PCW+E+
Sbjct: 382 IFNNQEFAQLLAQSVNHGFETVYELTKMCTIRMSFVKGWGAEYHRQDVTSTPCWIEI 438
>gi|47778931 SMAD, mothers against DPP homolog 5 [Homo sapiens]
Length = 465
Score = 91.7 bits (226), Expect = 1e-18
Identities = 108/415 (26%), Positives = 170/415 (40%), Gaps = 104/415 (25%)
Query: 98 SVLKKLKERQ--LELLLQAVESRGGTRTACLLLPGRLDCRLGPGAPAGAQPAQPPSSYSL 155
+++KKLK+++ +E L +A+ S G + C+ +P LD RL Q L
Sbjct: 37 ALVKKLKKKKGAMEELEKALSSPGQP-SKCVTIPRSLDGRL-----------QVSHRKGL 84
Query: 156 P-LLLCKVFRWPDLRHSSEVKRLCCCESYGKINPELVCC--------------------- 193
P ++ C+V+RWPDL+ E+K L CE + VC
Sbjct: 85 PHVIYCRVWRWPDLQSHHELKPLDICEFPFGSKQKEVCINPYHYKRVESPVLPPVLVPRH 144
Query: 194 ---NPHH-----LSRLCELESPPPPYSRYPMDF---------LKPTADCPDAVPSS---- 232
NP H L E P + +P F L P + P + SS
Sbjct: 145 NEFNPQHSLLVQFRNLSHNEPHMPQNATFPDSFHQPNNTPFPLSPNSPYPPSPASSTYPN 204
Query: 233 --------------AETGGTNYLAPG---GLSDSQLL------------------LEP-- 255
A+T Y+ P G +SQ + ++P
Sbjct: 205 SPASSGPGSPFQLPADTPPPAYMPPDDQMGQDNSQPMDTSNNMIPQIMPSISSRDVQPVA 264
Query: 256 -GDRSHWCVVAYWEEKTRVGRLYCVQEPSL--DIFYDLPQGNG--FCLGQLNSDNKSQLV 310
+ HWC + Y+E RVG + S+ D F D P N FCLG L++ N++ +
Sbjct: 265 YEEPKHWCSIVYYELNNRVGEAFHASSTSVLVDGFTD-PSNNKSRFCLGLLSNVNRNSTI 323
Query: 311 QKVRSKIGCGIQLTREVDGVWVYNRSSYPIFIKSATLD-NPDSRTLLVHKVFPGFSIKAF 369
+ R IG G+ L V+ S IF++S + + V K+ S+K F
Sbjct: 324 ENTRRHIGKGVHLYYVGGEVYAECLSDSSIFVQSRNCNFHHGFHPTTVCKIPSSCSLKIF 383
Query: 370 DYEK-AYSLQRPNDHEF--MQQPWTGFTVQISFVKGWGQCYTRQFISSCPCWLEV 421
+ ++ A L + +H F + + T+++SFVKGWG Y RQ ++S PCW+E+
Sbjct: 384 NNQEFAQLLAQSVNHGFEAVYELTKMCTIRMSFVKGWGAEYHRQDVTSTPCWIEI 438
>gi|47778929 SMAD, mothers against DPP homolog 5 [Homo sapiens]
Length = 465
Score = 91.7 bits (226), Expect = 1e-18
Identities = 108/415 (26%), Positives = 170/415 (40%), Gaps = 104/415 (25%)
Query: 98 SVLKKLKERQ--LELLLQAVESRGGTRTACLLLPGRLDCRLGPGAPAGAQPAQPPSSYSL 155
+++KKLK+++ +E L +A+ S G + C+ +P LD RL Q L
Sbjct: 37 ALVKKLKKKKGAMEELEKALSSPGQP-SKCVTIPRSLDGRL-----------QVSHRKGL 84
Query: 156 P-LLLCKVFRWPDLRHSSEVKRLCCCESYGKINPELVCC--------------------- 193
P ++ C+V+RWPDL+ E+K L CE + VC
Sbjct: 85 PHVIYCRVWRWPDLQSHHELKPLDICEFPFGSKQKEVCINPYHYKRVESPVLPPVLVPRH 144
Query: 194 ---NPHH-----LSRLCELESPPPPYSRYPMDF---------LKPTADCPDAVPSS---- 232
NP H L E P + +P F L P + P + SS
Sbjct: 145 NEFNPQHSLLVQFRNLSHNEPHMPQNATFPDSFHQPNNTPFPLSPNSPYPPSPASSTYPN 204
Query: 233 --------------AETGGTNYLAPG---GLSDSQLL------------------LEP-- 255
A+T Y+ P G +SQ + ++P
Sbjct: 205 SPASSGPGSPFQLPADTPPPAYMPPDDQMGQDNSQPMDTSNNMIPQIMPSISSRDVQPVA 264
Query: 256 -GDRSHWCVVAYWEEKTRVGRLYCVQEPSL--DIFYDLPQGNG--FCLGQLNSDNKSQLV 310
+ HWC + Y+E RVG + S+ D F D P N FCLG L++ N++ +
Sbjct: 265 YEEPKHWCSIVYYELNNRVGEAFHASSTSVLVDGFTD-PSNNKSRFCLGLLSNVNRNSTI 323
Query: 311 QKVRSKIGCGIQLTREVDGVWVYNRSSYPIFIKSATLD-NPDSRTLLVHKVFPGFSIKAF 369
+ R IG G+ L V+ S IF++S + + V K+ S+K F
Sbjct: 324 ENTRRHIGKGVHLYYVGGEVYAECLSDSSIFVQSRNCNFHHGFHPTTVCKIPSSCSLKIF 383
Query: 370 DYEK-AYSLQRPNDHEF--MQQPWTGFTVQISFVKGWGQCYTRQFISSCPCWLEV 421
+ ++ A L + +H F + + T+++SFVKGWG Y RQ ++S PCW+E+
Sbjct: 384 NNQEFAQLLAQSVNHGFEAVYELTKMCTIRMSFVKGWGAEYHRQDVTSTPCWIEI 438
>gi|47778925 SMAD, mothers against DPP homolog 5 [Homo sapiens]
Length = 465
Score = 91.7 bits (226), Expect = 1e-18
Identities = 108/415 (26%), Positives = 170/415 (40%), Gaps = 104/415 (25%)
Query: 98 SVLKKLKERQ--LELLLQAVESRGGTRTACLLLPGRLDCRLGPGAPAGAQPAQPPSSYSL 155
+++KKLK+++ +E L +A+ S G + C+ +P LD RL Q L
Sbjct: 37 ALVKKLKKKKGAMEELEKALSSPGQP-SKCVTIPRSLDGRL-----------QVSHRKGL 84
Query: 156 P-LLLCKVFRWPDLRHSSEVKRLCCCESYGKINPELVCC--------------------- 193
P ++ C+V+RWPDL+ E+K L CE + VC
Sbjct: 85 PHVIYCRVWRWPDLQSHHELKPLDICEFPFGSKQKEVCINPYHYKRVESPVLPPVLVPRH 144
Query: 194 ---NPHH-----LSRLCELESPPPPYSRYPMDF---------LKPTADCPDAVPSS---- 232
NP H L E P + +P F L P + P + SS
Sbjct: 145 NEFNPQHSLLVQFRNLSHNEPHMPQNATFPDSFHQPNNTPFPLSPNSPYPPSPASSTYPN 204
Query: 233 --------------AETGGTNYLAPG---GLSDSQLL------------------LEP-- 255
A+T Y+ P G +SQ + ++P
Sbjct: 205 SPASSGPGSPFQLPADTPPPAYMPPDDQMGQDNSQPMDTSNNMIPQIMPSISSRDVQPVA 264
Query: 256 -GDRSHWCVVAYWEEKTRVGRLYCVQEPSL--DIFYDLPQGNG--FCLGQLNSDNKSQLV 310
+ HWC + Y+E RVG + S+ D F D P N FCLG L++ N++ +
Sbjct: 265 YEEPKHWCSIVYYELNNRVGEAFHASSTSVLVDGFTD-PSNNKSRFCLGLLSNVNRNSTI 323
Query: 311 QKVRSKIGCGIQLTREVDGVWVYNRSSYPIFIKSATLD-NPDSRTLLVHKVFPGFSIKAF 369
+ R IG G+ L V+ S IF++S + + V K+ S+K F
Sbjct: 324 ENTRRHIGKGVHLYYVGGEVYAECLSDSSIFVQSRNCNFHHGFHPTTVCKIPSSCSLKIF 383
Query: 370 DYEK-AYSLQRPNDHEF--MQQPWTGFTVQISFVKGWGQCYTRQFISSCPCWLEV 421
+ ++ A L + +H F + + T+++SFVKGWG Y RQ ++S PCW+E+
Sbjct: 384 NNQEFAQLLAQSVNHGFEAVYELTKMCTIRMSFVKGWGAEYHRQDVTSTPCWIEI 438
>gi|223029444 mothers against decapentaplegic homolog 3 isoform 4
[Homo sapiens]
Length = 230
Score = 88.6 bits (218), Expect = 1e-17
Identities = 65/204 (31%), Positives = 105/204 (51%), Gaps = 12/204 (5%)
Query: 232 SAETGGTNYLAPGGLSDSQ--LLLEPG---DRSHWCVVAYWEEKTRVGRLYCVQEPSLDI 286
S + G N L+P +S + L L+P + + WC ++Y+E RVG + +PS+ +
Sbjct: 4 SMDAGSPN-LSPNPMSPAHNNLDLQPVTYCEPAFWCSISYYELNQRVGETFHASQPSMTV 62
Query: 287 --FYDLPQGNGFCLGQLNSDNKSQLVQKVRSKIGCGIQLTREVDGVWVYNRSSYPIFIKS 344
F D FCLG L++ N++ V+ R IG G++L V+ S IF++S
Sbjct: 63 DGFTDPSNSERFCLGLLSNVNRNAAVELTRRHIGRGVRLYYIGGEVFAECLSDSAIFVQS 122
Query: 345 ATLDNPDS-RTLLVHKVFPGFSIKAFDYEKAYSL--QRPND-HEFMQQPWTGFTVQISFV 400
+ V K+ PG ++K F+ ++ +L Q N E + Q T+++SFV
Sbjct: 123 PNCNQRYGWHPATVCKIPPGCNLKIFNNQEFAALLAQSVNQGFEAVYQLTRMCTIRMSFV 182
Query: 401 KGWGQCYTRQFISSCPCWLEVIFN 424
KGWG Y RQ ++S PCW+E+ N
Sbjct: 183 KGWGAEYRRQTVTSTPCWIELHLN 206
>gi|4885457 mothers against decapentaplegic homolog 4 [Homo sapiens]
Length = 552
Score = 87.8 bits (216), Expect = 2e-17
Identities = 62/214 (28%), Positives = 95/214 (44%), Gaps = 60/214 (28%)
Query: 260 HWCVVAYWEEKTRVGRLYCVQEP----SLDIFYDLPQGNGFCLGQLNSDNKSQLVQKVRS 315
+WC +AY+E +VG + V ++D + D G+ FCLGQL++ ++++ +++ R
Sbjct: 322 YWCSIAYFEMDVQVGETFKVPSSCPIVTVDGYVDPSGGDRFCLGQLSNVHRTEAIERARL 381
Query: 316 KIGCGIQLTREVDG-VWVYNRSSYPIFIKSATLDNPDSRTL--LVHKVFPGFSIKAFDYE 372
IG G+QL + +G VWV S + +F++S LD R VHK++P IK FD
Sbjct: 382 HIGKGVQLECKGEGDVWVRCLSDHAVFVQSYYLDREAGRAPGDAVHKIYPSAYIKVFDLR 441
Query: 373 KAYSLQRPNDHEFMQQ--------------------PWTGFT------------------ 394
+ H MQQ P G
Sbjct: 442 QC--------HRQMQQQAATAQAAAAAQAAAVAGNIPGPGSVGGIAPAISLSAAAGIGVD 493
Query: 395 -------VQISFVKGWGQCYTRQFISSCPCWLEV 421
+++SFVKGWG Y RQ I PCW+E+
Sbjct: 494 DLRRLCILRMSFVKGWGPDYPRQSIKETPCWIEI 527
Score = 53.9 bits (128), Expect = 3e-07
Identities = 35/118 (29%), Positives = 59/118 (50%), Gaps = 13/118 (11%)
Query: 86 GGAEADLKALTHSVLKKLKERQLEL--LLQAVESRGGTRTACLLLPGRLDCRLGPGAPAG 143
G +E K S++KKLKE++ EL L+ A+ + G + C+ + LD RL G
Sbjct: 30 GESETFAKRAIESLVKKLKEKKDELDSLITAITTNGAHPSKCVTIQRTLDGRLQVAGRKG 89
Query: 144 AQPAQPPSSYSLPLLLCKVFRWPDLRHSSEVKRLCCCESYGKINPELVCCNPHHLSRL 201
++ +++RWPDL H +E+K + C+ + + VC NP+H R+
Sbjct: 90 FPH----------VIYARLWRWPDL-HKNELKHVKYCQYAFDLKCDSVCVNPYHYERV 136
>gi|110347449 POU domain, class 4, transcription factor 1 [Homo
sapiens]
Length = 419
Score = 50.4 bits (119), Expect = 3e-06
Identities = 27/64 (42%), Positives = 30/64 (46%), Gaps = 3/64 (4%)
Query: 18 APGGEDEEEGAGGGGGGGELRGEGATDSRAHGAGGGGPGRAGCCLGKAVRGAKGHHHPHP 77
A GG +G GGGGG G G G G GGGGPG G G + G H HPH
Sbjct: 137 AAGGGGAHDGPGGGGGPG---GGGGPGGGPGGGGGGGPGGGGGGPGGGLLGGSAHPHPHM 193
Query: 78 PAAG 81
+ G
Sbjct: 194 HSLG 197
>gi|52632383 heterogeneous nuclear ribonucleoprotein L isoform a
[Homo sapiens]
Length = 589
Score = 43.5 bits (101), Expect = 4e-04
Identities = 31/89 (34%), Positives = 37/89 (41%), Gaps = 21/89 (23%)
Query: 11 RRLWRSRAPGGEDEEEGA-------GGGGGGGELRGEGATDSRA------------HGAG 51
RRL + + P + GA GGGGGGG G G+ RA HG G
Sbjct: 14 RRLEQRQQPDEQRRRSGAMVKMAAAGGGGGGGRYYGGGSEGGRAPKRLKTDNAGDQHGGG 73
Query: 52 GGGPGRAGCCLGKAVRGAKGHHHPHPPAA 80
GGG G AG G G + + PH A
Sbjct: 74 GGGGGGAGAAGGGG--GGENYDDPHKTPA 100
>gi|4503119 cancer/testis antigen 1B [Homo sapiens]
Length = 180
Score = 42.0 bits (97), Expect = 0.001
Identities = 32/92 (34%), Positives = 38/92 (41%), Gaps = 4/92 (4%)
Query: 24 EEEGAGGGGGGGELRGEGATD-SRAHGAGGGGPGRAGCCLGKAVRGAKGHHHPHPPAAGA 82
+ EG G GG G+ G G G GGPG AG G+ RGA G P GA
Sbjct: 2 QAEGRGTGGSTGDADGPGGPGIPDGPGGNAGGPGEAGATGGRGPRGA-GAARASGPGGGA 60
Query: 83 --GAAGGAEADLKALTHSVLKKLKERQLELLL 112
G GGA + L + + R LE L
Sbjct: 61 PRGPHGGAASGLNGCCRCGARGPESRLLEFYL 92
Score = 34.7 bits (78), Expect = 0.17
Identities = 22/52 (42%), Positives = 23/52 (44%), Gaps = 11/52 (21%)
Query: 19 PGGEDEEEGAGGGGGGGELRGEGATDSRAHGAGGGGP---------GRAGCC 61
PGG G G GG RG GA +RA G GGG P G GCC
Sbjct: 27 PGGNAGGPGEAGATGGRGPRGAGA--ARASGPGGGAPRGPHGGAASGLNGCC 76
>gi|21281685 cancer/testis antigen 1A [Homo sapiens]
Length = 180
Score = 42.0 bits (97), Expect = 0.001
Identities = 32/92 (34%), Positives = 38/92 (41%), Gaps = 4/92 (4%)
Query: 24 EEEGAGGGGGGGELRGEGATD-SRAHGAGGGGPGRAGCCLGKAVRGAKGHHHPHPPAAGA 82
+ EG G GG G+ G G G GGPG AG G+ RGA G P GA
Sbjct: 2 QAEGRGTGGSTGDADGPGGPGIPDGPGGNAGGPGEAGATGGRGPRGA-GAARASGPGGGA 60
Query: 83 --GAAGGAEADLKALTHSVLKKLKERQLELLL 112
G GGA + L + + R LE L
Sbjct: 61 PRGPHGGAASGLNGCCRCGARGPESRLLEFYL 92
Score = 34.7 bits (78), Expect = 0.17
Identities = 22/52 (42%), Positives = 23/52 (44%), Gaps = 11/52 (21%)
Query: 19 PGGEDEEEGAGGGGGGGELRGEGATDSRAHGAGGGGP---------GRAGCC 61
PGG G G GG RG GA +RA G GGG P G GCC
Sbjct: 27 PGGNAGGPGEAGATGGRGPRGAGA--ARASGPGGGAPRGPHGGAASGLNGCC 76
>gi|24586686 voltage-dependent calcium channel gamma-8 subunit [Homo
sapiens]
Length = 425
Score = 42.0 bits (97), Expect = 0.001
Identities = 27/60 (45%), Positives = 29/60 (48%), Gaps = 7/60 (11%)
Query: 27 GAGGGGGGGELRGEGATDSRAHGAGGGGPGRAGCCLGKAVRGAKGH---HHPHPPAAGAG 83
GAGGGGGG GA A GAGGGG G G + GA G H+ P AG G
Sbjct: 324 GAGGGGGG----AVGAFGGAAGGAGGGGGGGGGAGAERDRGGASGFLTLHNAFPKEAGGG 379
Score = 33.9 bits (76), Expect = 0.29
Identities = 28/88 (31%), Positives = 33/88 (37%), Gaps = 9/88 (10%)
Query: 20 GGEDEEEGAGGGGGGGELRGEGATDSRAHGAG-----GGGPGRAGCCLGKAVRGAKGHHH 74
GG G GGGGGG G GA R +G P AG + V G
Sbjct: 337 GGAAGGAGGGGGGGG----GAGAERDRGGASGFLTLHNAFPKEAGGGVTVTVTGPPAPPA 392
Query: 75 PHPPAAGAGAAGGAEADLKALTHSVLKK 102
P PPA A A G + A + L +
Sbjct: 393 PAPPAPSAPAPGTLAKEAAASNTNTLNR 420
Score = 31.6 bits (70), Expect = 1.4
Identities = 31/101 (30%), Positives = 37/101 (36%), Gaps = 21/101 (20%)
Query: 2 FRTKRSALVRRLWRSRAPGGEDEEEGAGGGGGG-----------GELRGEGATDSRAHGA 50
FR +R + R RS P + G GG G +G+ + GA
Sbjct: 268 FRYRRRS--RSSSRSSEPSPSRDASPGGPGGPGFASTDISMYTLSRDPSKGSVAAGLAGA 325
Query: 51 GGGGPGRAGCCLGKAVRGAKGHHHPHPPAAGAGAAGGAEAD 91
GGGG G G G A GA G G G GAE D
Sbjct: 326 GGGGGGAVG-AFGGAAGGAGG-------GGGGGGGAGAERD 358
>gi|4507163 SRY (sex determining region Y)-box 4 [Homo sapiens]
Length = 474
Score = 41.6 bits (96), Expect = 0.001
Identities = 30/84 (35%), Positives = 35/84 (41%), Gaps = 11/84 (13%)
Query: 16 SRAPGGEDEEEGAGGGGGGGELRGEGATDSRAHGAGGGG--------PGRAGCCLGKAVR 67
S PG + ++ GG GGGG G G S A G GGG P + C K
Sbjct: 148 SSKPGEKGDK--VGGSGGGGHGGGGGGGSSNAGGGGGGASGGGANSKPAQKKSCGSKVAG 205
Query: 68 GAKGH-HHPHPPAAGAGAAGGAEA 90
GA G PH AG GG +A
Sbjct: 206 GAGGGVSKPHAKLILAGGGGGGKA 229
Score = 32.7 bits (73), Expect = 0.64
Identities = 43/158 (27%), Positives = 52/158 (32%), Gaps = 28/158 (17%)
Query: 20 GGEDEEEGAGGGGGGGELRGEGATD----SRAHGAGGGGPGRAGCCLGKAVRGAKGHHHP 75
GG G GGG GG + A S+ G GGG + L A G G
Sbjct: 172 GGSSNAGGGGGGASGGGANSKPAQKKSCGSKVAGGAGGGVSKPHAKLILAGGGGGGKAAA 231
Query: 76 HPPAAGAGAAGGAEADL---KALTHSVLKKLKERQLELLLQAVESRGGTRTACLLLPGR- 131
A+ A GA A L A H L K + A S + +A L PG+
Sbjct: 232 AAAASFAAEQAGAAALLPLGAAADHHSLYKARTPS----ASASASSAASASAALAAPGKH 287
Query: 132 --------------LDCRLGP--GAPAGAQPAQPPSSY 153
L P G AGA P+ P Y
Sbjct: 288 LAEKKVKRVYLFGGLGTSSSPVGGVGAGADPSDPLGLY 325
>gi|109452587 family with sequence similarity 98, member B isoform 1
[Homo sapiens]
Length = 433
Score = 41.6 bits (96), Expect = 0.001
Identities = 27/77 (35%), Positives = 29/77 (37%), Gaps = 3/77 (3%)
Query: 14 WRSRAPGGEDEEEGAGGGGGGGELRGEGATDSRAHGAGG---GGPGRAGCCLGKAVRGAK 70
W+ R GG GGGGGGG G G G GG GG G G G G +
Sbjct: 325 WQKRQEGGGGRGGWGGGGGGGGRGGGGGGGGRGGWGGGGGGWGGGGGGGGGWGGGGGGGR 384
Query: 71 GHHHPHPPAAGAGAAGG 87
G G G GG
Sbjct: 385 GGFQGRGDYGGRGGYGG 401
Score = 40.4 bits (93), Expect = 0.003
Identities = 23/61 (37%), Positives = 27/61 (44%)
Query: 27 GAGGGGGGGELRGEGATDSRAHGAGGGGPGRAGCCLGKAVRGAKGHHHPHPPAAGAGAAG 86
G GGGGGGG G G R G G G G G+ G +G+ P+ G G G
Sbjct: 365 GWGGGGGGGGGWGGGGGGGRGGFQGRGDYGGRGGYGGRGGYGGRGYGDPYGGGGGGGGGG 424
Query: 87 G 87
G
Sbjct: 425 G 425
Score = 35.4 bits (80), Expect = 0.099
Identities = 25/69 (36%), Positives = 27/69 (39%), Gaps = 5/69 (7%)
Query: 19 PGGEDEEEGAGGGGGGGELRGEGATDSRAHGAGGGGPGRAGCCLGKAVRGAKGHHHPHPP 78
P + +EG GG GG G G G G GGGG GR G G G G
Sbjct: 323 PPWQKRQEGGGGRGGWGGGGGGG-----GRGGGGGGGGRGGWGGGGGGWGGGGGGGGGWG 377
Query: 79 AAGAGAAGG 87
G G GG
Sbjct: 378 GGGGGGRGG 386
Score = 33.5 bits (75), Expect = 0.38
Identities = 17/39 (43%), Positives = 18/39 (46%)
Query: 21 GEDEEEGAGGGGGGGELRGEGATDSRAHGAGGGGPGRAG 59
G + G GG GG G G G D G GGGG G G
Sbjct: 389 GRGDYGGRGGYGGRGGYGGRGYGDPYGGGGGGGGGGGGG 427
Score = 32.0 bits (71), Expect = 1.1
Identities = 18/49 (36%), Positives = 20/49 (40%), Gaps = 3/49 (6%)
Query: 14 WRSRAPGGEDEEEGAGGGGGGGELRGEGATDSRAHG---AGGGGPGRAG 59
W GG +G G GG G G G R +G GGGG G G
Sbjct: 376 WGGGGGGGRGGFQGRGDYGGRGGYGGRGGYGGRGYGDPYGGGGGGGGGG 424
>gi|23510368 homeobox D11 [Homo sapiens]
Length = 338
Score = 41.2 bits (95), Expect = 0.002
Identities = 44/142 (30%), Positives = 55/142 (38%), Gaps = 38/142 (26%)
Query: 30 GGGGGGELRGEGATDSRAHGAGGGGPGRAGCCLGKAVRGAKGHHHPHPPAAGAGAAGGAE 89
GGGGGG G G+ GGGPG G G G + P+ AA A AA A
Sbjct: 77 GGGGGGSAGG---------GSSGGGPGGGG--------GGAGGYAPYYAAAAAAAAAAAA 119
Query: 90 ADLKALTHSVLKKLKERQLELLLQAVE--------SRGGTRTACL---------LLPGRL 132
A+ A+ +L R ++L +A E G A +LP
Sbjct: 120 AEEAAMQRELLPPAGRRP-DVLFKAPEPVCAAPGPPHGPAGAASNFYSAVGRNGILPQGF 178
Query: 133 D--CRLGPGAP-AGAQPAQPPS 151
D PG P AG QP PP+
Sbjct: 179 DQFYEAAPGPPFAGPQPPPPPA 200
Score = 29.3 bits (64), Expect = 7.1
Identities = 17/42 (40%), Positives = 22/42 (52%), Gaps = 5/42 (11%)
Query: 23 DEEEGAGGGGGGGELRGEGATDSR--AHGAGGGG---PGRAG 59
D GAGGGGG + ++ + A G+GG G PG AG
Sbjct: 212 DPRTGAGGGGGSPCTKATPGSEPKGAAEGSGGDGEGPPGEAG 253
>gi|25777671 protein phosphatase 1, regulatory subunit 10 [Homo
sapiens]
Length = 940
Score = 41.2 bits (95), Expect = 0.002
Identities = 26/67 (38%), Positives = 27/67 (40%), Gaps = 4/67 (5%)
Query: 21 GEDEEEGAGGGGGGGELRGEGATDSRAHGAGGGGPGRAGCCLGKAVRGAKGHHHPHPPAA 80
G EG GGG G G EG S GGGG R G + G GH P
Sbjct: 766 GHRPHEGPGGGMGSGHRPHEGPGGSM----GGGGGHRPHEGPGGGISGGSGHRPHEGPGG 821
Query: 81 GAGAAGG 87
G GA GG
Sbjct: 822 GMGAGGG 828
Score = 32.3 bits (72), Expect = 0.84
Identities = 24/73 (32%), Positives = 29/73 (39%), Gaps = 3/73 (4%)
Query: 20 GGEDEEEGAGGGGGGGELRGEGATDSRAHGAGGGGPGRAGCCLGKAVRGAKGHHHPHPPA 79
GG EG GGG GG G + G G GG R G ++ G+ G H PH
Sbjct: 795 GGHRPHEGPGGGISGGS--GHRPHEGPGGGMGAGGGHRPHEGPGGSMGGS-GGHRPHEGP 851
Query: 80 AGAGAAGGAEADL 92
G G D+
Sbjct: 852 GHGGPHGHRPHDV 864
Score = 30.4 bits (67), Expect = 3.2
Identities = 23/68 (33%), Positives = 28/68 (41%), Gaps = 14/68 (20%)
Query: 20 GGEDEEEGAGGGGGGGELRGEGATDSRAHGAGGGGPGRAGCCLGKAVRGAKGHHHPHPPA 79
GG+ +G G GG +RG G GPG G+ RG G+ P PP
Sbjct: 675 GGDPFWDGPGDPMRGGPMRG------------GPGPGPGPYHRGRGGRG--GNEPPPPPP 720
Query: 80 AGAGAAGG 87
GA GG
Sbjct: 721 PFRGARGG 728
Score = 30.0 bits (66), Expect = 4.2
Identities = 23/71 (32%), Positives = 25/71 (35%), Gaps = 4/71 (5%)
Query: 19 PGGEDEEEGAGGGGGGGELRGEGATDSRAHGAGGGGP--GRAGCCLGKAVRGAKGHHHPH 76
PG G GG GG G GGGP GR G G + G GH
Sbjct: 698 PGPGPYHRGRGGRGGNEPPPPPPPFRGARGGRSGGGPPNGRGG--PGGGMVGGGGHRPHE 755
Query: 77 PPAAGAGAAGG 87
P G G + G
Sbjct: 756 GPGGGMGNSSG 766
Score = 29.6 bits (65), Expect = 5.5
Identities = 20/60 (33%), Positives = 23/60 (38%), Gaps = 7/60 (11%)
Query: 29 GGGGGGGELRGEGATDSRAHGAGGGGPGRAGCCLGKAVRGAKGHHHPHPPAAGAGAAGGA 88
GG GGG G G G GGG G G + G G+ H P G G G+
Sbjct: 727 GGRSGGGPPNGRG-------GPGGGMVGGGGHRPHEGPGGGMGNSSGHRPHEGPGGGMGS 779
Score = 29.6 bits (65), Expect = 5.5
Identities = 27/84 (32%), Positives = 30/84 (35%), Gaps = 12/84 (14%)
Query: 16 SRAPGGEDEEEGAGGGGGGGELRGEGATDSRAHGAGG----GGPGRAGCCLGKA--VRGA 69
S G E GG G GG R G+GG GPG G + V G
Sbjct: 808 SGGSGHRPHEGPGGGMGAGGGHRPHEGPGGSMGGSGGHRPHEGPGHGGPHGHRPHDVPGH 867
Query: 70 KGHHHPHPPA------AGAGAAGG 87
+GH H PP G G GG
Sbjct: 868 RGHDHRGPPPHEHRGHDGPGHGGG 891
Score = 28.9 bits (63), Expect = 9.3
Identities = 22/60 (36%), Positives = 26/60 (43%), Gaps = 5/60 (8%)
Query: 30 GGGGGGELRGEGATDSRAH-GAGGGGPGRAGCCLGKAVRGAKGH-HHPHPPAAGAGAAGG 87
GG GGG + G G R H G GGG +G + G G H PH G+ GG
Sbjct: 739 GGPGGGMVGGGG---HRPHEGPGGGMGNSSGHRPHEGPGGGMGSGHRPHEGPGGSMGGGG 795
>gi|18375613 dachshund homolog 1 isoform b [Homo sapiens]
Length = 558
Score = 41.2 bits (95), Expect = 0.002
Identities = 29/103 (28%), Positives = 40/103 (38%), Gaps = 7/103 (6%)
Query: 29 GGGGGGGELRGEGATDSRAHGAGGGGPGRAGCCLGKAVRGAKGHHHPHPPAAGAGAAGGA 88
GGGGGGG G G++ + G GGGG L A G+ G G +AGG
Sbjct: 75 GGGGGGGSGGGGGSSGNGGGGGGGGGGSNCNPNLAAASNGSGG-------GGGGISAGGG 127
Query: 89 EADLKALTHSVLKKLKERQLELLLQAVESRGGTRTACLLLPGR 131
A + S + S + ++C LPG+
Sbjct: 128 VASSTPINASTGSSSSSSSSSSSSSSSSSSSSSSSSCGPLPGK 170
Score = 35.0 bits (79), Expect = 0.13
Identities = 16/37 (43%), Positives = 20/37 (54%)
Query: 20 GGEDEEEGAGGGGGGGELRGEGATDSRAHGAGGGGPG 56
GG G GGGGGGG + ++G+GGGG G
Sbjct: 85 GGGSSGNGGGGGGGGGGSNCNPNLAAASNGSGGGGGG 121
Score = 33.1 bits (74), Expect = 0.49
Identities = 18/41 (43%), Positives = 18/41 (43%), Gaps = 1/41 (2%)
Query: 20 GGEDEEEGAGGGGGGG-ELRGEGATDSRAHGAGGGGPGRAG 59
GG G GGGGGGG A S G GGGG G
Sbjct: 86 GGSSGNGGGGGGGGGGSNCNPNLAAASNGSGGGGGGISAGG 126
>gi|18375611 dachshund homolog 1 isoform a [Homo sapiens]
Length = 706
Score = 41.2 bits (95), Expect = 0.002
Identities = 29/103 (28%), Positives = 40/103 (38%), Gaps = 7/103 (6%)
Query: 29 GGGGGGGELRGEGATDSRAHGAGGGGPGRAGCCLGKAVRGAKGHHHPHPPAAGAGAAGGA 88
GGGGGGG G G++ + G GGGG L A G+ G G +AGG
Sbjct: 75 GGGGGGGSGGGGGSSGNGGGGGGGGGGSNCNPNLAAASNGSGG-------GGGGISAGGG 127
Query: 89 EADLKALTHSVLKKLKERQLELLLQAVESRGGTRTACLLLPGR 131
A + S + S + ++C LPG+
Sbjct: 128 VASSTPINASTGSSSSSSSSSSSSSSSSSSSSSSSSCGPLPGK 170
Score = 35.0 bits (79), Expect = 0.13
Identities = 16/37 (43%), Positives = 20/37 (54%)
Query: 20 GGEDEEEGAGGGGGGGELRGEGATDSRAHGAGGGGPG 56
GG G GGGGGGG + ++G+GGGG G
Sbjct: 85 GGGSSGNGGGGGGGGGGSNCNPNLAAASNGSGGGGGG 121
Score = 33.1 bits (74), Expect = 0.49
Identities = 18/41 (43%), Positives = 18/41 (43%), Gaps = 1/41 (2%)
Query: 20 GGEDEEEGAGGGGGGG-ELRGEGATDSRAHGAGGGGPGRAG 59
GG G GGGGGGG A S G GGGG G
Sbjct: 86 GGSSGNGGGGGGGGGGSNCNPNLAAASNGSGGGGGGISAGG 126
>gi|18375609 dachshund homolog 1 isoform c [Homo sapiens]
Length = 504
Score = 41.2 bits (95), Expect = 0.002
Identities = 29/103 (28%), Positives = 40/103 (38%), Gaps = 7/103 (6%)
Query: 29 GGGGGGGELRGEGATDSRAHGAGGGGPGRAGCCLGKAVRGAKGHHHPHPPAAGAGAAGGA 88
GGGGGGG G G++ + G GGGG L A G+ G G +AGG
Sbjct: 75 GGGGGGGSGGGGGSSGNGGGGGGGGGGSNCNPNLAAASNGSGG-------GGGGISAGGG 127
Query: 89 EADLKALTHSVLKKLKERQLELLLQAVESRGGTRTACLLLPGR 131
A + S + S + ++C LPG+
Sbjct: 128 VASSTPINASTGSSSSSSSSSSSSSSSSSSSSSSSSCGPLPGK 170
Score = 35.0 bits (79), Expect = 0.13
Identities = 16/37 (43%), Positives = 20/37 (54%)
Query: 20 GGEDEEEGAGGGGGGGELRGEGATDSRAHGAGGGGPG 56
GG G GGGGGGG + ++G+GGGG G
Sbjct: 85 GGGSSGNGGGGGGGGGGSNCNPNLAAASNGSGGGGGG 121
Score = 33.1 bits (74), Expect = 0.49
Identities = 18/41 (43%), Positives = 18/41 (43%), Gaps = 1/41 (2%)
Query: 20 GGEDEEEGAGGGGGGG-ELRGEGATDSRAHGAGGGGPGRAG 59
GG G GGGGGGG A S G GGGG G
Sbjct: 86 GGSSGNGGGGGGGGGGSNCNPNLAAASNGSGGGGGGISAGG 126
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.319 0.138 0.450
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 20,942,882
Number of Sequences: 37866
Number of extensions: 1207913
Number of successful extensions: 13067
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 228
Number of HSP's successfully gapped in prelim test: 310
Number of HSP's that attempted gapping in prelim test: 7717
Number of HSP's gapped (non-prelim): 3239
length of query: 426
length of database: 18,247,518
effective HSP length: 105
effective length of query: 321
effective length of database: 14,271,588
effective search space: 4581179748
effective search space used: 4581179748
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.