Search of human proteins with 5031839

Search of human proteins with 5031839

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|5031839 keratin 6A [Homo sapiens]
         (564 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|5031839 keratin 6A [Homo sapiens]                                 1103   0.0  
gi|155969697 keratin 6C [Homo sapiens]                               1092   0.0  
gi|119703753 keratin 6B [Homo sapiens]                               1091   0.0  
gi|119395754 keratin 5 [Homo sapiens]                                 863   0.0  
gi|153791158 keratin 75 [Homo sapiens]                                778   0.0  
gi|109148552 keratin 3 [Homo sapiens]                                 679   0.0  
gi|153791670 keratin 76 [Homo sapiens]                                663   0.0  
gi|119395750 keratin 1 [Homo sapiens]                                 657   0.0  
gi|109255249 keratin 4 [Homo sapiens]                                 642   0.0  
gi|47132620 keratin 2 [Homo sapiens]                                  632   0.0  
gi|32567786 keratin 6L [Homo sapiens]                                 628   e-180
gi|194018511 keratin 77 [Homo sapiens]                                589   e-168
gi|28173564 keratin 73 [Homo sapiens]                                 579   e-165
gi|15618995 keratin 71 [Homo sapiens]                                 568   e-162
gi|28372503 keratin 72 isoform 1 [Homo sapiens]                       567   e-162
gi|226246663 keratin 72 isoform 1 [Homo sapiens]                      567   e-162
gi|148612803 keratin 6 irs4 [Homo sapiens]                            560   e-159
gi|15431316 keratin, hair, basic, 4 [Homo sapiens]                    525   e-149
gi|4504919 keratin 8 [Homo sapiens]                                   523   e-148
gi|67782365 keratin 7 [Homo sapiens]                                  519   e-147
gi|89357932 keratin 5b [Homo sapiens]                                 492   e-139
gi|226246665 keratin 72 isoform 2 [Homo sapiens]                      487   e-137
gi|27477127 keratin 82 [Homo sapiens]                                 452   e-127
gi|4504935 keratin 85 [Homo sapiens]                                  449   e-126
gi|169790853 keratin, hair, basic, 1 [Homo sapiens]                   433   e-121
gi|239755818 PREDICTED: hypothetical protein isoform 2 [Homo sap...   427   e-119
gi|239755816 PREDICTED: hypothetical protein isoform 1 [Homo sap...   427   e-119
gi|239755814 PREDICTED: hypothetical protein isoform 3 [Homo sap...   427   e-119
gi|14318422 keratin 86 [Homo sapiens]                                 427   e-119
gi|169790841 keratin 83 [Homo sapiens]                                422   e-118

>gi|5031839 keratin 6A [Homo sapiens]
          Length = 564

 Score = 1103 bits (2852), Expect = 0.0
 Identities = 564/564 (100%), Positives = 564/564 (100%)

Query: 1   MASTSTTIRSHSSSRRGFSANSARLPGVSRSGFSSVSVSRSRGSGGLGGACGGAGFGSRS 60
           MASTSTTIRSHSSSRRGFSANSARLPGVSRSGFSSVSVSRSRGSGGLGGACGGAGFGSRS
Sbjct: 1   MASTSTTIRSHSSSRRGFSANSARLPGVSRSGFSSVSVSRSRGSGGLGGACGGAGFGSRS 60

Query: 61  LYGLGGSKRISIGGGSCAISGGYGSRAGGSYGFGGAGSGFGFGGGAGIGFGLGGGAGLAG 120
           LYGLGGSKRISIGGGSCAISGGYGSRAGGSYGFGGAGSGFGFGGGAGIGFGLGGGAGLAG
Sbjct: 61  LYGLGGSKRISIGGGSCAISGGYGSRAGGSYGFGGAGSGFGFGGGAGIGFGLGGGAGLAG 120

Query: 121 GFGGPGFPVCPPGGIQEVTVNQSLLTPLNLQIDPTIQRVRAEEREQIKTLNNKFASFIDK 180
           GFGGPGFPVCPPGGIQEVTVNQSLLTPLNLQIDPTIQRVRAEEREQIKTLNNKFASFIDK
Sbjct: 121 GFGGPGFPVCPPGGIQEVTVNQSLLTPLNLQIDPTIQRVRAEEREQIKTLNNKFASFIDK 180

Query: 181 VRFLEQQNKVLETKWTLLQEQGTKTVRQNLEPLFEQYINNLRRQLDSIVGERGRLDSELR 240
           VRFLEQQNKVLETKWTLLQEQGTKTVRQNLEPLFEQYINNLRRQLDSIVGERGRLDSELR
Sbjct: 181 VRFLEQQNKVLETKWTLLQEQGTKTVRQNLEPLFEQYINNLRRQLDSIVGERGRLDSELR 240

Query: 241 GMQDLVEDFKNKYEDEINKRTAAENEFVTLKKDVDAAYMNKVELQAKADTLTDEINFLRA 300
           GMQDLVEDFKNKYEDEINKRTAAENEFVTLKKDVDAAYMNKVELQAKADTLTDEINFLRA
Sbjct: 241 GMQDLVEDFKNKYEDEINKRTAAENEFVTLKKDVDAAYMNKVELQAKADTLTDEINFLRA 300

Query: 301 LYDAELSQMQTHISDTSVVLSMDNNRNLDLDSIIAEVKAQYEEIAQRSRAEAESWYQTKY 360
           LYDAELSQMQTHISDTSVVLSMDNNRNLDLDSIIAEVKAQYEEIAQRSRAEAESWYQTKY
Sbjct: 301 LYDAELSQMQTHISDTSVVLSMDNNRNLDLDSIIAEVKAQYEEIAQRSRAEAESWYQTKY 360

Query: 361 EELQVTAGRHGDDLRNTKQEIAEINRMIQRLRSEIDHVKKQCANLQAAIADAEQRGEMAL 420
           EELQVTAGRHGDDLRNTKQEIAEINRMIQRLRSEIDHVKKQCANLQAAIADAEQRGEMAL
Sbjct: 361 EELQVTAGRHGDDLRNTKQEIAEINRMIQRLRSEIDHVKKQCANLQAAIADAEQRGEMAL 420

Query: 421 KDAKNKLEGLEDALQKAKQDLARLLKEYQELMNVKLALDVEIATYRKLLEGEECRLNGEG 480
           KDAKNKLEGLEDALQKAKQDLARLLKEYQELMNVKLALDVEIATYRKLLEGEECRLNGEG
Sbjct: 421 KDAKNKLEGLEDALQKAKQDLARLLKEYQELMNVKLALDVEIATYRKLLEGEECRLNGEG 480

Query: 481 VGQVNISVVQSTVSSGYGGASGVGSGLGLGGGSSYSYGSGLGVGGGFSSSSGRAIGGGLS 540
           VGQVNISVVQSTVSSGYGGASGVGSGLGLGGGSSYSYGSGLGVGGGFSSSSGRAIGGGLS
Sbjct: 481 VGQVNISVVQSTVSSGYGGASGVGSGLGLGGGSSYSYGSGLGVGGGFSSSSGRAIGGGLS 540

Query: 541 SVGGGSSTIKYTTTSSSSRKSYKH 564
           SVGGGSSTIKYTTTSSSSRKSYKH
Sbjct: 541 SVGGGSSTIKYTTTSSSSRKSYKH 564


>gi|155969697 keratin 6C [Homo sapiens]
          Length = 564

 Score = 1092 bits (2823), Expect = 0.0
 Identities = 555/564 (98%), Positives = 561/564 (99%)

Query: 1   MASTSTTIRSHSSSRRGFSANSARLPGVSRSGFSSVSVSRSRGSGGLGGACGGAGFGSRS 60
           MASTSTTIRSHSSSRRGFSANSARLPGVSRSGFSS+SVSRSRGSGGLGGACGGAGFGSRS
Sbjct: 1   MASTSTTIRSHSSSRRGFSANSARLPGVSRSGFSSISVSRSRGSGGLGGACGGAGFGSRS 60

Query: 61  LYGLGGSKRISIGGGSCAISGGYGSRAGGSYGFGGAGSGFGFGGGAGIGFGLGGGAGLAG 120
           LYGLGGSKRISIGGGSCAISGGYGSRAGGSYGFGGAGSGFGFGGGAGIGFGLGGGAGLAG
Sbjct: 61  LYGLGGSKRISIGGGSCAISGGYGSRAGGSYGFGGAGSGFGFGGGAGIGFGLGGGAGLAG 120

Query: 121 GFGGPGFPVCPPGGIQEVTVNQSLLTPLNLQIDPTIQRVRAEEREQIKTLNNKFASFIDK 180
           GFGGPGFPVCPPGGIQEVTVNQSLLTPLNLQIDP IQRVRAEEREQIKTLNNKFASFIDK
Sbjct: 121 GFGGPGFPVCPPGGIQEVTVNQSLLTPLNLQIDPAIQRVRAEEREQIKTLNNKFASFIDK 180

Query: 181 VRFLEQQNKVLETKWTLLQEQGTKTVRQNLEPLFEQYINNLRRQLDSIVGERGRLDSELR 240
           VRFLEQQNKVL+TKWTLLQEQGTKTVRQNLEPLFEQYINNLRRQLDSIVGERGRLDSELR
Sbjct: 181 VRFLEQQNKVLDTKWTLLQEQGTKTVRQNLEPLFEQYINNLRRQLDSIVGERGRLDSELR 240

Query: 241 GMQDLVEDFKNKYEDEINKRTAAENEFVTLKKDVDAAYMNKVELQAKADTLTDEINFLRA 300
            MQDLVED KNKYEDEINKRTAAENEFVTLKKDVDAAYMNKVELQAKADTLTDEINFLRA
Sbjct: 241 NMQDLVEDLKNKYEDEINKRTAAENEFVTLKKDVDAAYMNKVELQAKADTLTDEINFLRA 300

Query: 301 LYDAELSQMQTHISDTSVVLSMDNNRNLDLDSIIAEVKAQYEEIAQRSRAEAESWYQTKY 360
           LYDAELSQMQTHISDTSVVLSMDNNRNLDLDSIIAEVKAQYEEIAQRSRAEAESWYQTKY
Sbjct: 301 LYDAELSQMQTHISDTSVVLSMDNNRNLDLDSIIAEVKAQYEEIAQRSRAEAESWYQTKY 360

Query: 361 EELQVTAGRHGDDLRNTKQEIAEINRMIQRLRSEIDHVKKQCANLQAAIADAEQRGEMAL 420
           EELQVTAGRHGDDLRNTKQEIAEINRMIQRLRSEIDHVKKQCA+LQAAIADAEQRGEMAL
Sbjct: 361 EELQVTAGRHGDDLRNTKQEIAEINRMIQRLRSEIDHVKKQCASLQAAIADAEQRGEMAL 420

Query: 421 KDAKNKLEGLEDALQKAKQDLARLLKEYQELMNVKLALDVEIATYRKLLEGEECRLNGEG 480
           KDAKNKLEGLEDALQKAKQDLARLLKEYQELMNVKLALDVEIATYRKLLEGEECRLNGEG
Sbjct: 421 KDAKNKLEGLEDALQKAKQDLARLLKEYQELMNVKLALDVEIATYRKLLEGEECRLNGEG 480

Query: 481 VGQVNISVVQSTVSSGYGGASGVGSGLGLGGGSSYSYGSGLGVGGGFSSSSGRAIGGGLS 540
           VGQVN+SVVQST+SSGYGGASGVGSGLGLGGGSSYSYGSGLG+GGGFSSSSGRAIGGGLS
Sbjct: 481 VGQVNVSVVQSTISSGYGGASGVGSGLGLGGGSSYSYGSGLGIGGGFSSSSGRAIGGGLS 540

Query: 541 SVGGGSSTIKYTTTSSSSRKSYKH 564
           SVGGGSSTIKYTTTSSSSRKSYKH
Sbjct: 541 SVGGGSSTIKYTTTSSSSRKSYKH 564


>gi|119703753 keratin 6B [Homo sapiens]
          Length = 564

 Score = 1091 bits (2822), Expect = 0.0
 Identities = 556/564 (98%), Positives = 560/564 (99%)

Query: 1   MASTSTTIRSHSSSRRGFSANSARLPGVSRSGFSSVSVSRSRGSGGLGGACGGAGFGSRS 60
           MASTSTTIRSHSSSRRGFSANSARLPGVSRSGFSS+SVSRSRGSGGLGGACGGAGFGSRS
Sbjct: 1   MASTSTTIRSHSSSRRGFSANSARLPGVSRSGFSSISVSRSRGSGGLGGACGGAGFGSRS 60

Query: 61  LYGLGGSKRISIGGGSCAISGGYGSRAGGSYGFGGAGSGFGFGGGAGIGFGLGGGAGLAG 120
           LYGLGGSKRISIGGGSCAISGGYGSRAGGSYGFGGAGSGFGFGGGAGIGFGLGGGAGLAG
Sbjct: 61  LYGLGGSKRISIGGGSCAISGGYGSRAGGSYGFGGAGSGFGFGGGAGIGFGLGGGAGLAG 120

Query: 121 GFGGPGFPVCPPGGIQEVTVNQSLLTPLNLQIDPTIQRVRAEEREQIKTLNNKFASFIDK 180
           GFGGPGFPVCPPGGIQEVTVNQSLLTPLNLQIDP IQRVRAEEREQIKTLNNKFASFIDK
Sbjct: 121 GFGGPGFPVCPPGGIQEVTVNQSLLTPLNLQIDPAIQRVRAEEREQIKTLNNKFASFIDK 180

Query: 181 VRFLEQQNKVLETKWTLLQEQGTKTVRQNLEPLFEQYINNLRRQLDSIVGERGRLDSELR 240
           VRFLEQQNKVL+TKWTLLQEQGTKTVRQNLEPLFEQYINNLRRQLD+IVGERGRLDSELR
Sbjct: 181 VRFLEQQNKVLDTKWTLLQEQGTKTVRQNLEPLFEQYINNLRRQLDNIVGERGRLDSELR 240

Query: 241 GMQDLVEDFKNKYEDEINKRTAAENEFVTLKKDVDAAYMNKVELQAKADTLTDEINFLRA 300
            MQDLVED KNKYEDEINKRTAAENEFVTLKKDVDAAYMNKVELQAKADTLTDEINFLRA
Sbjct: 241 NMQDLVEDLKNKYEDEINKRTAAENEFVTLKKDVDAAYMNKVELQAKADTLTDEINFLRA 300

Query: 301 LYDAELSQMQTHISDTSVVLSMDNNRNLDLDSIIAEVKAQYEEIAQRSRAEAESWYQTKY 360
           LYDAELSQMQTHISDTSVVLSMDNNRNLDLDSIIAEVKAQYEEIAQRSRAEAESWYQTKY
Sbjct: 301 LYDAELSQMQTHISDTSVVLSMDNNRNLDLDSIIAEVKAQYEEIAQRSRAEAESWYQTKY 360

Query: 361 EELQVTAGRHGDDLRNTKQEIAEINRMIQRLRSEIDHVKKQCANLQAAIADAEQRGEMAL 420
           EELQ+TAGRHGDDLRNTKQEIAEINRMIQRLRSEIDHVKKQCANLQAAIADAEQRGEMAL
Sbjct: 361 EELQITAGRHGDDLRNTKQEIAEINRMIQRLRSEIDHVKKQCANLQAAIADAEQRGEMAL 420

Query: 421 KDAKNKLEGLEDALQKAKQDLARLLKEYQELMNVKLALDVEIATYRKLLEGEECRLNGEG 480
           KDAKNKLEGLEDALQKAKQDLARLLKEYQELMNVKLALDVEIATYRKLLEGEECRLNGEG
Sbjct: 421 KDAKNKLEGLEDALQKAKQDLARLLKEYQELMNVKLALDVEIATYRKLLEGEECRLNGEG 480

Query: 481 VGQVNISVVQSTVSSGYGGASGVGSGLGLGGGSSYSYGSGLGVGGGFSSSSGRAIGGGLS 540
           VGQVNISVVQSTVSSGYGGASGVGSGLGLGGGSSYSYGSGLGVGGGFSSSSGRA GGGLS
Sbjct: 481 VGQVNISVVQSTVSSGYGGASGVGSGLGLGGGSSYSYGSGLGVGGGFSSSSGRATGGGLS 540

Query: 541 SVGGGSSTIKYTTTSSSSRKSYKH 564
           SVGGGSSTIKYTTTSSSSRKSYKH
Sbjct: 541 SVGGGSSTIKYTTTSSSSRKSYKH 564


>gi|119395754 keratin 5 [Homo sapiens]
          Length = 590

 Score =  863 bits (2231), Expect = 0.0
 Identities = 454/588 (77%), Positives = 489/588 (83%), Gaps = 27/588 (4%)

Query: 3   STSTTIRSHSSSRRGFSANSARLPGVSRSGFSSVSVSRSRGSGGLG-----GACGGAGFG 57
           S  +++   S   R FS  SA  P VSR+ F+SVS S   G GG G     GACG  G+G
Sbjct: 2   SRQSSVSFRSGGSRSFSTASAITPSVSRTSFTSVSRSGGGGGGGFGRVSLAGACGVGGYG 61

Query: 58  SRSLYGLGGSKRISIGGGSCAISGGYGSRAGGSYGFGG-AGSGFGFGGGAGIGFGLGGGA 116
           SRSLY LGGSKRISI     +    +G+ AGG YGFGG AGSGFGFGGGAG GFGLGGGA
Sbjct: 62  SRSLYNLGGSKRISISTSGGSFRNRFGAGAGGGYGFGGGAGSGFGFGGGAGGGFGLGGGA 121

Query: 117 GLAGGFGGPGFPVCPPGGIQEVTVNQSLLTPLNLQIDPTIQRVRAEEREQIKTLNNKFAS 176
           G  GGFGGPGFPVCPPGGIQEVTVNQSLLTPLNLQIDP+IQRVR EEREQIKTLNNKFAS
Sbjct: 122 GFGGGFGGPGFPVCPPGGIQEVTVNQSLLTPLNLQIDPSIQRVRTEEREQIKTLNNKFAS 181

Query: 177 FIDKVRFLEQQNKVLETKWTLLQEQGTKTVRQNLEPLFEQYINNLRRQLDSIVGERGRLD 236
           FIDKVRFLEQQNKVL+TKWTLLQEQGTKTVRQNLEPLFEQYINNLRRQLDSIVGERGRLD
Sbjct: 182 FIDKVRFLEQQNKVLDTKWTLLQEQGTKTVRQNLEPLFEQYINNLRRQLDSIVGERGRLD 241

Query: 237 SELRGMQDLVEDFKNKYEDEINKRTAAENEFVTLKKDVDAAYMNKVELQAKADTLTDEIN 296
           SELR MQDLVEDFKNKYEDEINKRT AENEFV LKKDVDAAYMNKVEL+AK D L DEIN
Sbjct: 242 SELRNMQDLVEDFKNKYEDEINKRTTAENEFVMLKKDVDAAYMNKVELEAKVDALMDEIN 301

Query: 297 FLRALYDAELSQMQTHISDTSVVLSMDNNRNLDLDSIIAEVKAQYEEIAQRSRAEAESWY 356
           F++  +DAELSQMQTH+SDTSVVLSMDNNRNLDLDSIIAEVKAQYEEIA RSR EAESWY
Sbjct: 302 FMKMFFDAELSQMQTHVSDTSVVLSMDNNRNLDLDSIIAEVKAQYEEIANRSRTEAESWY 361

Query: 357 QTKYEELQVTAGRHGDDLRNTKQEIAEINRMIQRLRSEIDHVKKQCANLQAAIADAEQRG 416
           QTKYEELQ TAGRHGDDLRNTK EI+E+NRMIQRLR+EID+VKKQCANLQ AIADAEQRG
Sbjct: 362 QTKYEELQQTAGRHGDDLRNTKHEISEMNRMIQRLRAEIDNVKKQCANLQNAIADAEQRG 421

Query: 417 EMALKDAKNKLEGLEDALQKAKQDLARLLKEYQELMNVKLALDVEIATYRKLLEGEECRL 476
           E+ALKDA+NKL  LE+ALQKAKQD+ARLL+EYQELMN KLALDVEIATYRKLLEGEECRL
Sbjct: 422 ELALKDARNKLAELEEALQKAKQDMARLLREYQELMNTKLALDVEIATYRKLLEGEECRL 481

Query: 477 NGEGVGQVNISVVQSTVSSGYGGASGVGSGL----------GLGGGSSYSY--------- 517
           +GEGVG VNISVV S+VSSGYG  SG G GL          GL GGSS SY         
Sbjct: 482 SGEGVGPVNISVVTSSVSSGYGSGSGYGGGLGGGLGGGLGGGLAGGSSGSYYSSSSGGVG 541

Query: 518 -GSGLGVGG-GFSSSSGRAIGGGLSSVGGGSSTIKYTTTSSSSRKSYK 563
            G GL VGG GFS+SSGR +G G  S GG SS++K+ +T+SSSRKS+K
Sbjct: 542 LGGGLSVGGSGFSASSGRGLGVGFGSGGGSSSSVKFVSTTSSSRKSFK 589


>gi|153791158 keratin 75 [Homo sapiens]
          Length = 551

 Score =  778 bits (2008), Expect = 0.0
 Identities = 412/573 (71%), Positives = 467/573 (81%), Gaps = 34/573 (5%)

Query: 3   STSTTIRSHSSSRRGFSANSARLPGVSRSGFSSVSVSRSR-GSGGLGG-ACGGAGFGSRS 60
           S  ++I   S SRRGFS  SA  P   RS FSSVSV+RS  GSGGLG  +  GA FGSRS
Sbjct: 2   SRQSSITFQSGSRRGFSTTSAITPAAGRSRFSSVSVARSAAGSGGLGRISSAGASFGSRS 61

Query: 61  LYGLGGSKRISIGGGSCAISGGYGSRAGGSYGFGGAGSGFGFGGGAGIGFGLGGGAGLAG 120
           LY LGG+KR+SI G   +   G+G RA   +G     SGFG+GGG G            G
Sbjct: 62  LYNLGGAKRVSINGCGSSCRSGFGGRASNRFG---VNSGFGYGGGVG------------G 106

Query: 121 GFGGPGFPVCPPGGIQEVTVNQSLLTPLNLQIDPTIQRVRAEEREQIKTLNNKFASFIDK 180
           GF GP FPVCPPGGIQEVTVNQSLLTPL+LQIDPTIQRVRAEEREQIKTLNNKFASFIDK
Sbjct: 107 GFSGPSFPVCPPGGIQEVTVNQSLLTPLHLQIDPTIQRVRAEEREQIKTLNNKFASFIDK 166

Query: 181 VRFLEQQNKVLETKWTLLQEQGTKTVRQNLEPLFEQYINNLRRQLDSIVGERGRLDSELR 240
           VRFLEQQNKVLETKW LLQEQG++TVRQNLEPLF+ Y + LRRQL+SI  ERGRL++ELR
Sbjct: 167 VRFLEQQNKVLETKWALLQEQGSRTVRQNLEPLFDSYTSELRRQLESITTERGRLEAELR 226

Query: 241 GMQDLVEDFKNKYEDEINKRTAAENEFVTLKKDVDAAYMNKVELQAKADTLTDEINFLRA 300
            MQD+VEDFK +YEDEINKRTAAENEFV LKKDVDAAYMNKVEL+AK  +L +EINF+ +
Sbjct: 227 NMQDVVEDFKVRYEDEINKRTAAENEFVALKKDVDAAYMNKVELEAKVKSLPEEINFIHS 286

Query: 301 LYDAELSQMQTHISDTSVVLSMDNNRNLDLDSIIAEVKAQYEEIAQRSRAEAESWYQTKY 360
           ++DAELSQ+QT + DTSVVLSMDNNRNLDLDSIIAEVKAQYE+IA RSRAEAESWYQTKY
Sbjct: 287 VFDAELSQLQTQVGDTSVVLSMDNNRNLDLDSIIAEVKAQYEDIANRSRAEAESWYQTKY 346

Query: 361 EELQVTAGRHGDDLRNTKQEIAEINRMIQRLRSEIDHVKKQCANLQAAIADAEQRGEMAL 420
           EELQVTAGRHGDDLRNTKQEI+E+NRMIQRLR+EID VKKQC++LQ AIADAEQRGE+AL
Sbjct: 347 EELQVTAGRHGDDLRNTKQEISEMNRMIQRLRAEIDSVKKQCSSLQTAIADAEQRGELAL 406

Query: 421 KDAKNKLEGLEDALQKAKQDLARLLKEYQELMNVKLALDVEIATYRKLLEGEECRLNGEG 480
           KDA+ KL  LE+ALQKAKQD+ARLL+EYQELMN+KLALDVEIATYRKLLEGEECRL+GEG
Sbjct: 407 KDARAKLVDLEEALQKAKQDMARLLREYQELMNIKLALDVEIATYRKLLEGEECRLSGEG 466

Query: 481 VGQVNISVVQSTVSSGYGGASGVGSG-LGLGGGSSYSY--------GSGLGVGGGFSSSS 531
           V  VNISVV ST+SSGYG  S +G G LGLGGGS YS+        G+GLG G GFS++S
Sbjct: 467 VSPVNISVVTSTLSSGYGSGSSIGGGNLGLGGGSGYSFTTSGGHSLGAGLG-GSGFSATS 525

Query: 532 GRAIGGGLSSVGGGSSTIKYTTTSSSSRKSYKH 564
            R +       GG  S++K+ +T+SSS+KSY H
Sbjct: 526 NRGL-------GGSGSSVKFVSTTSSSQKSYTH 551


>gi|109148552 keratin 3 [Homo sapiens]
          Length = 628

 Score =  679 bits (1753), Expect = 0.0
 Identities = 382/583 (65%), Positives = 426/583 (73%), Gaps = 47/583 (8%)

Query: 9   RSHSSSRRGFSANSARLPGVSRSGFSSVSVSRSRGSGGLGGACGGAGFGSRSLYGLGGSK 68
           ++     +GFS  SA + G SR   S V+ S   G G  G   G  GFGSRSLY LGG+K
Sbjct: 7   KTSGGGSQGFSGRSAVVSGSSR--MSCVAHSGGAGGGAYGFRSGAGGFGSRSLYNLGGNK 64

Query: 69  RISI------------GGG--SCAISGGYGSRAGGSYGFG-------GAGSGFGFGGGAG 107
            ISI            GGG  SCA +GGYG   G  YG G       G G G GFGG  G
Sbjct: 65  SISISVAAGGSRAGGFGGGRSSCAFAGGYGGGFGSGYGGGFGGGFGGGRGMGGGFGGAGG 124

Query: 108 IG----------FGLGGGAGLAGGFGGPGFPVCP--------PGGIQEVTVNQSLLTPLN 149
            G          FG  GG G +GGFGGPG    P        PGGIQEVT+NQSLL PLN
Sbjct: 125 FGGAGGFGGAGGFGGPGGFGGSGGFGGPGSLGSPGGFGPGGFPGGIQEVTINQSLLQPLN 184

Query: 150 LQIDPTIQRVRAEEREQIKTLNNKFASFIDKVRFLEQQNKVLETKWTLLQEQGTKTVR-- 207
           ++IDP I +V+A+EREQIKTLNNKFASFIDKVRFLEQQNKVLETKW LLQ+QGT ++   
Sbjct: 185 VEIDPQIGQVKAQEREQIKTLNNKFASFIDKVRFLEQQNKVLETKWNLLQQQGTSSISGT 244

Query: 208 QNLEPLFEQYINNLRRQLDSIVGERGRLDSELRGMQDLVEDFKNKYEDEINKRTAAENEF 267
            NLEPLFE +IN LR  LD+I+GERGRLDSEL+ M+DLVEDFK KYEDEINKRTAAENEF
Sbjct: 245 NNLEPLFENHINYLRSYLDNILGERGRLDSELKNMEDLVEDFKKKYEDEINKRTAAENEF 304

Query: 268 VTLKKDVDAAYMNKVELQAKADTLTDEINFLRALYDAELSQMQTHISDTSVVLSMDNNRN 327
           VTLKKDVD+AYMNKVELQAK D L DEI+FLR LYDAELSQMQ+HISDTSVVLSMDNNR+
Sbjct: 305 VTLKKDVDSAYMNKVELQAKVDALIDEIDFLRTLYDAELSQMQSHISDTSVVLSMDNNRS 364

Query: 328 LDLDSIIAEVKAQYEEIAQRSRAEAESWYQTKYEELQVTAGRHGDDLRNTKQEIAEINRM 387
           LDLDSIIAEV+AQYE+IAQRS+AEAE+ YQTK  ELQ TAGRHGDDLRNTK EI E+NRM
Sbjct: 365 LDLDSIIAEVRAQYEDIAQRSKAEAEALYQTKLGELQTTAGRHGDDLRNTKSEIIELNRM 424

Query: 388 IQRLRSEIDHVKKQCANLQAAIADAEQRGEMALKDAKNKLEGLEDALQKAKQDLARLLKE 447
           IQRLR+EI+ VKKQ ANLQ AIA+AEQ GEMALKDA  KL+ L+ ALQ+AK DLARLL++
Sbjct: 425 IQRLRAEIEGVKKQNANLQTAIAEAEQHGEMALKDANAKLQELQAALQQAKDDLARLLRD 484

Query: 448 YQELMNVKLALDVEIATYRKLLEGEECRLNGEGVGQVNISVVQSTVSS----GYGGASGV 503
           YQELMNVKLALDVEIATYRKLLEGEE R++GE    V+ISVV S+ +S    GYGG  G 
Sbjct: 485 YQELMNVKLALDVEIATYRKLLEGEEYRMSGECPSAVSISVVSSSTTSASAGGYGGGYGG 544

Query: 504 GSGLGLGGGSSYSYGSGLGVGGGFSSSSGRAIGGGLSSVGGGS 546
           G G GLGGG S   GSG G G G     G   GGG S   GGS
Sbjct: 545 GMGGGLGGGFSAGGGSGSGFGRGGGGGIGGGFGGGSSGFSGGS 587



 Score = 54.7 bits (130), Expect = 2e-07
 Identities = 42/113 (37%), Positives = 51/113 (45%), Gaps = 26/113 (23%)

Query: 15  RRGFSANSARLPGVSRSGFSSVSVSRSRGSGGLGGACGGAGFGSRSLYGLGGSKRISIGG 74
           R+       R+ G   S  S   VS S  S   GG  GG G G              +GG
Sbjct: 503 RKLLEGEEYRMSGECPSAVSISVVSSSTTSASAGGYGGGYGGG--------------MGG 548

Query: 75  GSCAISGGYGSRAGGSYGFGGAGSGFGFGGGAGIGFGLGGGAGLAGGFGGPGF 127
           G   + GG+ +        GG+GSGFG GGG GIG G GGG+  +G  GG GF
Sbjct: 549 G---LGGGFSAG-------GGSGSGFGRGGGGGIGGGFGGGS--SGFSGGSGF 589


>gi|153791670 keratin 76 [Homo sapiens]
          Length = 638

 Score =  663 bits (1711), Expect = 0.0
 Identities = 383/592 (64%), Positives = 431/592 (72%), Gaps = 56/592 (9%)

Query: 9   RSHSSSRRGFSANSARLPGVSRSGFSSVSVSRSRGSGGLGGACG---GAG-FGSRSLYGL 64
           +S S   +GFS  SA + G SR       V+RS G+GG  GACG   GAG FGSRSLY L
Sbjct: 8   KSFSGRSQGFSGRSAVVSGSSRMS----CVARSGGAGG--GACGFRSGAGSFGSRSLYNL 61

Query: 65  GGSKRISI------------GGG--SCAISGGYGSRAGGSYGFGGAGSGFGFGGGAGIGF 110
           G +K ISI            GGG  SC  +GGYG   GGSYG      GFG G G G GF
Sbjct: 62  GSNKSISISVAAGSSRAGGFGGGRSSCGFAGGYGGGFGGSYG-----GGFGGGRGVGSGF 116

Query: 111 GLGGGAGLAGGFGGPGFPVCP--------------PGGIQEVTVNQSLLTPLNLQIDPTI 156
           G  GG G AGGFGGPG    P              PGGIQEV VNQSLL PLN++IDP I
Sbjct: 117 GGAGGFGGAGGFGGPGVFGGPGSFGGPGGFGPGGFPGGIQEVIVNQSLLQPLNVEIDPQI 176

Query: 157 QRVRAEEREQIKTLNNKFASFIDKVRFLEQQNKVLETKWTLLQEQGTKTVRQNLEPLFEQ 216
            +V+A+EREQIKTLNNKFASFIDKVRFLEQQNKVLETKW LLQ+Q T +   +LEP FE 
Sbjct: 177 GQVKAQEREQIKTLNNKFASFIDKVRFLEQQNKVLETKWELLQQQTTGSGPSSLEPCFES 236

Query: 217 YINNLRRQLDSIVGERGRLDSELRGMQDLVEDFKNKYEDEINKRTAAENEFVTLKKDVDA 276
           YI+ L +QLDS++GERG L+ EL+ MQDLVEDFK KYEDEINKRTAAENEFV LKKDVDA
Sbjct: 237 YISFLCKQLDSLLGERGNLEGELKSMQDLVEDFKKKYEDEINKRTAAENEFVGLKKDVDA 296

Query: 277 AYMNKVELQAKADTLTDEINFLRALYDAELSQMQTHISDTSVVLSMDNNRNLDLDSIIAE 336
           A+MNKVELQAK D+LTDE++FLR LY+ ELSQMQ+H SDTSVVLSMDNNR LDL SIIAE
Sbjct: 297 AFMNKVELQAKVDSLTDEVSFLRTLYEMELSQMQSHASDTSVVLSMDNNRCLDLGSIIAE 356

Query: 337 VKAQYEEIAQRSRAEAESWYQTKYEELQVTAGRHGDDLRNTKQEIAEINRMIQRLRSEID 396
           V+AQYEEIAQRS++EAE+ YQTK  ELQ TAGRHGDDLRNTK EI E+NRMIQRLR+EI+
Sbjct: 357 VRAQYEEIAQRSKSEAEALYQTKLGELQTTAGRHGDDLRNTKSEIMELNRMIQRLRAEIE 416

Query: 397 HVKKQCANLQAAIADAEQRGEMALKDAKNKLEGLEDALQKAKQDLARLLKEYQELMNVKL 456
           +VKKQ ANLQ AIA+AEQRGEMALKDA  KL+ L+ ALQKAK DLARLL++YQELMNVKL
Sbjct: 417 NVKKQNANLQTAIAEAEQRGEMALKDANAKLQDLQTALQKAKDDLARLLRDYQELMNVKL 476

Query: 457 ALDVEIATYRKLLEGEECRLNGEGVGQVNISVVQSTVSSG---------YGGASGVGSGL 507
           ALDVEIATYRKLLEGEECR++GE    V ISVV +  S+          +GG SG GSG 
Sbjct: 477 ALDVEIATYRKLLEGEECRMSGECQSAVCISVVSNVTSTSGSSGSSRGVFGGVSGSGSG- 535

Query: 508 GLGGGSSYSYGSGLGVGGGFSSSSGRAIGGGLSSVGGGSSTIKYTTTSSSSR 559
           G  GGSS S  SG GV GG  S  G    G   S GG  S+  Y ++SS SR
Sbjct: 536 GYKGGSSSSSSSGYGVSGGSGSGYGGVSSG---STGGRGSSGSYQSSSSGSR 584



 Score = 49.3 bits (116), Expect = 9e-06
 Identities = 41/117 (35%), Positives = 52/117 (44%), Gaps = 7/117 (5%)

Query: 1   MASTSTTIRSHSSSRRGFSANSARLPGVSRSGFSSVSVSRSRGSGGLGGACGGAGFGSRS 60
           +++ ++T  S  SSR  F   S    G  + G SS S S    SGG G   GG   GS  
Sbjct: 509 VSNVTSTSGSSGSSRGVFGGVSGSGSGGYKGGSSSSSSSGYGVSGGSGSGYGGVSSGSTG 568

Query: 61  LYGLGGSKRISI------GGGSCAIS-GGYGSRAGGSYGFGGAGSGFGFGGGAGIGF 110
             G  GS + S       G GS ++S  G GS +G     GG+G   G GG   I F
Sbjct: 569 GRGSSGSYQSSSSGSRLGGAGSISVSHSGMGSSSGSIQTSGGSGYKSGGGGSTSIRF 625



 Score = 46.6 bits (109), Expect = 6e-05
 Identities = 34/109 (31%), Positives = 43/109 (39%), Gaps = 5/109 (4%)

Query: 15  RRGFSANSARLPGVSRSGFSSVSVSRSRGSGGLGGACGGAGFGSRSLYGLGGSKRISIGG 74
           R+       R+ G  +S      VS    + G  G+  G  FG  S  G GG K    GG
Sbjct: 486 RKLLEGEECRMSGECQSAVCISVVSNVTSTSGSSGSSRGV-FGGVSGSGSGGYK----GG 540

Query: 75  GSCAISGGYGSRAGGSYGFGGAGSGFGFGGGAGIGFGLGGGAGLAGGFG 123
            S + S GYG   G   G+GG  SG   G G+   +         GG G
Sbjct: 541 SSSSSSSGYGVSGGSGSGYGGVSSGSTGGRGSSGSYQSSSSGSRLGGAG 589


>gi|119395750 keratin 1 [Homo sapiens]
          Length = 644

 Score =  657 bits (1695), Expect = 0.0
 Identities = 368/579 (63%), Positives = 425/579 (73%), Gaps = 32/579 (5%)

Query: 9   RSHSSSRRGFSANSARLPGVSRSGFSSVSVSRSRGSGGLGGACGGAG--------FGSRS 60
           RS   S  GFS+ SA +    R   SS S  RS G GG   +CGG G        FGSRS
Sbjct: 8   RSGYRSGGGFSSGSAGIINYQRRTTSS-STRRSGGGGGRFSSCGGGGGSFGAGGGFGSRS 66

Query: 61  LYGLGGSKRISI-----GGGSCAISGGYGSRAGGSYGFGGAG-SGFGFGGGAGIGFGLGG 114
           L  LGGSK ISI     GG      GGYG    G  GFGG G  G G GGG   GFG GG
Sbjct: 67  LVNLGGSKSISISVARGGGRGSGFGGGYGGGGFGGGGFGGGGFGGGGIGGGGFGGFGSGG 126

Query: 115 GAGLAGGFGGPGF-----PVCPPGGIQEVTVNQSLLTPLNLQIDPTIQRVRAEEREQIKT 169
           G    GGFGG G+     PVCPPGGIQEVT+NQSLL PLN++IDP IQ+V++ EREQIK+
Sbjct: 127 GGFGGGGFGGGGYGGGYGPVCPPGGIQEVTINQSLLQPLNVEIDPEIQKVKSREREQIKS 186

Query: 170 LNNKFASFIDKVRFLEQQNKVLETKWTLLQEQGTKTVRQNLEPLFEQYINNLRRQLDSIV 229
           LNN+FASFIDKVRFLEQQN+VL+TKW LLQ+  T T   NLEP FE +INNLRR++D + 
Sbjct: 187 LNNQFASFIDKVRFLEQQNQVLQTKWELLQQVDTSTRTHNLEPYFESFINNLRRRVDQLK 246

Query: 230 GERGRLDSELRGMQDLVEDFKNKYEDEINKRTAAENEFVTLKKDVDAAYMNKVELQAKAD 289
            ++ RLDSEL+ MQD+VED++NKYEDEINKRT AENEFVT+KKDVD AYM KV+LQAK D
Sbjct: 247 SDQSRLDSELKNMQDMVEDYRNKYEDEINKRTNAENEFVTIKKDVDGAYMTKVDLQAKLD 306

Query: 290 TLTDEINFLRALYDAELSQMQTHISDTSVVLSMDNNRNLDLDSIIAEVKAQYEEIAQRSR 349
            L  EI+FL ALY AELSQMQT IS+T+V+LSMDNNR+LDLDSIIAEVKAQYE+IAQ+S+
Sbjct: 307 NLQQEIDFLTALYQAELSQMQTQISETNVILSMDNNRSLDLDSIIAEVKAQYEDIAQKSK 366

Query: 350 AEAESWYQTKYEELQVTAGRHGDDLRNTKQEIAEINRMIQRLRSEIDHVKKQCANLQAAI 409
           AEAES YQ+KYEELQ+TAGRHGD +RN+K EI+E+NR+IQRLRSEID+VKKQ +NLQ +I
Sbjct: 367 AEAESLYQSKYEELQITAGRHGDSVRNSKIEISELNRVIQRLRSEIDNVKKQISNLQQSI 426

Query: 410 ADAEQRGEMALKDAKNKLEGLEDALQKAKQDLARLLKEYQELMNVKLALDVEIATYRKLL 469
           +DAEQRGE ALKDAKNKL  LEDALQ+AK+DLARLL++YQELMN KLALD+EIATYR LL
Sbjct: 427 SDAEQRGENALKDAKNKLNDLEDALQQAKEDLARLLRDYQELMNTKLALDLEIATYRTLL 486

Query: 470 EGEECRLNGEGVGQVNISVVQS-TVSSGYGGASGVGSGLGLGGGSSY-----SYGSGLGV 523
           EGEE R++GE    V++SV  S T  SG G   G G G G  GGSSY     SYGSG G 
Sbjct: 487 EGEESRMSGECAPNVSVSVSTSHTTISGGGSRGGGGGGYG-SGGSSYGSGGGSYGSGGGG 545

Query: 524 GGGFSS-----SSGRAIGGGLSSVGGGSSTIKYTTTSSS 557
           GGG  S     SS  + GG   S GGG     Y + SSS
Sbjct: 546 GGGRGSYGSGGSSYGSGGGSYGSGGGGGGHGSYGSGSSS 584



 Score = 63.5 bits (153), Expect = 5e-10
 Identities = 52/133 (39%), Positives = 58/133 (43%), Gaps = 8/133 (6%)

Query: 10  SHSSSRRGFSANSARLPGVSRSGFSSVSVSRSRGSGGLGGACGGAGFGSRSLYGLGGSKR 69
           S S+S    S   +R  G    G+ S   S   G G  G   GG G G R  YG GGS  
Sbjct: 504 SVSTSHTTISGGGSR--GGGGGGYGSGGSSYGSGGGSYGS--GGGGGGGRGSYGSGGSSY 559

Query: 70  ISIGG--GSCAISGGYGSRAGGSYGFGGAGSGFGFGGGAGIGFGLGGGA--GLAGGFGGP 125
            S GG  GS    GG+GS   GS   G  G   G GGG+  G G GGG+  G  GG G  
Sbjct: 560 GSGGGSYGSGGGGGGHGSYGSGSSSGGYRGGSGGGGGGSSGGRGSGGGSSGGSIGGRGSS 619

Query: 126 GFPVCPPGGIQEV 138
              V   GG   V
Sbjct: 620 SGGVKSSGGSSSV 632



 Score = 33.1 bits (74), Expect = 0.69
 Identities = 18/35 (51%), Positives = 21/35 (60%)

Query: 527 FSSSSGRAIGGGLSSVGGGSSTIKYTTTSSSSRKS 561
           FSS SG   GGG SS   G    +  TTSSS+R+S
Sbjct: 5   FSSRSGYRSGGGFSSGSAGIINYQRRTTSSSTRRS 39


>gi|109255249 keratin 4 [Homo sapiens]
          Length = 594

 Score =  642 bits (1655), Expect = 0.0
 Identities = 352/544 (64%), Positives = 412/544 (75%), Gaps = 36/544 (6%)

Query: 16  RGFSANSARLPGVSRSGFSSVSVSRSRGSGGLGGACGGAGFGSRSLYGLGGSKRISIGGG 75
           RGFS  SA + G  R  FSSVS+S      G  G C   GFGSRSLY L G+K IS+   
Sbjct: 87  RGFSCGSAIVGGGKRGAFSSVSMS------GGAGRCSSGGFGSRSLYNLRGNKSISMSVA 140

Query: 76  SCAISGGYGSRAGGSYGFGGAGSGFGFGGGAGIGFGLGGGAGLAGGFGGPGFPVCPPGGI 135
                   GSR G    FGGAG   GFG G   GFG GG  G   G GGPGFPVCP GGI
Sbjct: 141 --------GSRQGAC--FGGAG---GFGTG---GFG-GGFGGSFSGKGGPGFPVCPAGGI 183

Query: 136 QEVTVNQSLLTPLNLQIDPTIQRVRAEEREQIKTLNNKFASFIDKVRFLEQQNKVLETKW 195
           QEVT+NQSLLTPL+++IDP IQ+VR EEREQIK LNNKFASFIDKV+FLEQQNKVLETKW
Sbjct: 184 QEVTINQSLLTPLHVEIDPEIQKVRTEEREQIKLLNNKFASFIDKVQFLEQQNKVLETKW 243

Query: 196 TLLQEQGTKTVRQNLEPLFEQYINNLRRQLDSIVGERGRLDSELRGMQDLVEDFKNKYED 255
            LLQ+Q T T  +NLEPLFE Y++ LR+QLD++  ++GRL SEL+ MQD VEDFK KYE+
Sbjct: 244 NLLQQQTTTTSSKNLEPLFETYLSVLRKQLDTLGNDKGRLQSELKTMQDSVEDFKTKYEE 303

Query: 256 EINKRTAAENEFVTLKKDVDAAYMNKVELQAKADTLTDEINFLRALYDAELSQMQTHISD 315
           EINKRTAAEN+FV LKKDVDAAY+NKVEL+AK D+L DEINFL+ LYDAELSQMQTH+SD
Sbjct: 304 EINKRTAAENDFVVLKKDVDAAYLNKVELEAKVDSLNDEINFLKVLYDAELSQMQTHVSD 363

Query: 316 TSVVLSMDNNRNLDLDSIIAEVKAQYEEIAQRSRAEAESWYQTKYEELQVTAGRHGDDLR 375
           TSVVLSMDNNRNLDLDSIIAEV+AQYEEIAQRS+AEAE+ YQTK ++LQ++  +HGD+L+
Sbjct: 364 TSVVLSMDNNRNLDLDSIIAEVRAQYEEIAQRSKAEAEALYQTKVQQLQISVDQHGDNLK 423

Query: 376 NTKQEIAEINRMIQRLRSEIDHVKKQCANLQAAIADAEQRGEMALKDAKNKLEGLEDALQ 435
           NTK EIAE+NRMIQRLR+EI+++KKQC  LQ ++ADAEQRGE ALKDA +K   LE ALQ
Sbjct: 424 NTKSEIAELNRMIQRLRAEIENIKKQCQTLQVSVADAEQRGENALKDAHSKRVELEAALQ 483

Query: 436 KAKQDLARLLKEYQELMNVKLALDVEIATYRKLLEGEECRLNGEGVGQVNISVVQSTVSS 495
           +AK++LAR+L+EYQELM+VKLALD+EIATYRKLLEGEE R++GE    V+ISVV  + S+
Sbjct: 484 QAKEELARMLREYQELMSVKLALDIEIATYRKLLEGEEYRMSGECQSAVSISVVSGSTST 543

Query: 496 GYGGASGVGSGLGLGGGSSYSYGSGLGVGGGFSSSSGRAIGGGLSSVGGGSSTIKYTTTS 555
           G     G+  GLG G        SG G+  GF S SG   G G S  G  SS I  TTT 
Sbjct: 544 G-----GISGGLGSG--------SGFGLSSGFGSGSGSGFGFGGSVSGSSSSKIISTTTL 590

Query: 556 SSSR 559
           +  R
Sbjct: 591 NKRR 594


>gi|47132620 keratin 2 [Homo sapiens]
          Length = 639

 Score =  632 bits (1629), Expect = 0.0
 Identities = 357/586 (60%), Positives = 409/586 (69%), Gaps = 58/586 (9%)

Query: 16  RGFSANSARLPGVSRSGFSSVSVSRSRGSGGLGGACGGAGFGSRSLYGLGGSKRISI--- 72
           RGFS+ SA + G SR   SS S     G GG  G  GG GFGSRSL GLGG+K ISI   
Sbjct: 20  RGFSSGSAVVSGGSRRSTSSFSCLSRHGGGG--GGFGGGGFGSRSLVGLGGTKSISISVA 77

Query: 73  -GGGSCAISGGYGSRAGGSYG---FGGAGSGFGFGGGAGIGFGLG-----GGAGLAGGFG 123
            GGG    +GG+G R GG  G   FGG GSGF  GG  G GFG G     GG G  GG G
Sbjct: 78  GGGGGFGAAGGFGGRGGGFGGGSSFGG-GSGFSGGGFGGGGFGGGRFGGFGGPGGVGGLG 136

Query: 124 GPGF--PVCPPGGIQEVTVNQSLLTPLNLQIDPTIQRVRAEEREQIKTLNNKFASFIDKV 181
           GPG   P   PGGI EV+VNQSLL PLN+++DP IQ V+A+EREQIKTLNNKFASFIDKV
Sbjct: 137 GPGGFGPGGYPGGIHEVSVNQSLLQPLNVKVDPEIQNVKAQEREQIKTLNNKFASFIDKV 196

Query: 182 RFLEQQNKVLETKWTLLQEQGTKTVRQNLEPLFEQYINNLRRQLDSIVGERGRLDSELRG 241
           RFLEQQN+VL+TKW LLQ+    T   NLEP+F+ YI++L+R LD +  ER   +SEL  
Sbjct: 197 RFLEQQNQVLQTKWELLQQMNVGTRPINLEPIFQGYIDSLKRYLDGLTAERTSQNSELNN 256

Query: 242 MQDLVEDFKNKYEDEINKRTAAENEFVTLKKDVDAAYMNKVELQAKADTLTDEINFLRAL 301
           MQDLVED+K KYEDEINKRTAAEN+FVTLKKDVD AYM KVELQ+K D L  EI FL+ L
Sbjct: 257 MQDLVEDYKKKYEDEINKRTAAENDFVTLKKDVDNAYMIKVELQSKVDLLNQEIEFLKVL 316

Query: 302 YDAELSQMQTHISDTSVVLSMDNNRNLDLDSIIAEVKAQYEEIAQRSRAEAESWYQTKYE 361
           YDAE+SQ+   ++DT+V+LSMDN+RNLDLDSIIAEVKAQYEEIAQRS+ EAE+ Y +KYE
Sbjct: 317 YDAEISQIHQSVTDTNVILSMDNSRNLDLDSIIAEVKAQYEEIAQRSKEEAEALYHSKYE 376

Query: 362 ELQVTAGRHGDDLRNTKQEIAEINRMIQRLRSEIDHVKKQCANLQAAIADAEQRGEMALK 421
           ELQVT GRHGD L+  K EI+E+NR+IQRL+ EI HVKKQC N+Q AIADAEQRGE ALK
Sbjct: 377 ELQVTVGRHGDSLKEIKIEISELNRVIQRLQGEIAHVKKQCKNVQDAIADAEQRGEHALK 436

Query: 422 DAKNKLEGLEDALQKAKQDLARLLKEYQELMNVKLALDVEIATYRKLLEGEECRLNGEGV 481
           DA+NKL  LE+ALQ+AK+DLARLL++YQELMNVKLALDVEIATYRKLLEGEECR++G+  
Sbjct: 437 DARNKLNDLEEALQQAKEDLARLLRDYQELMNVKLALDVEIATYRKLLEGEECRMSGDLS 496

Query: 482 GQVNISVVQSTVSS--------------------GY---------------------GGA 500
             V +SV  ST+SS                    GY                     GG 
Sbjct: 497 SNVTVSVTSSTISSNVASKAAFGGSGGRGSSSGGGYSSGSSSYGSGGRQSGSRGGSGGGG 556

Query: 501 SGVGSGLGLGGGSSYSYGSGLGVGGGFSSSSGRAIGGGLSSVGGGS 546
           S  G G G GGGS   YGSG G  GG  S  G   GGG  S GGGS
Sbjct: 557 SISGGGYGSGGGSGGRYGSGGGSKGGSISGGGYGSGGGKHSSGGGS 602



 Score = 64.7 bits (156), Expect = 2e-10
 Identities = 52/135 (38%), Positives = 62/135 (45%), Gaps = 19/135 (14%)

Query: 4   TSTTIRSHSSSRRGFSANSARLPGVSRSGFSSVSVSR--------SRGSGGLGGACGGAG 55
           TS+TI S+ +S+  F  +  R    S  G+SS S S         SRG  G GG+  G G
Sbjct: 504 TSSTISSNVASKAAFGGSGGR-GSSSGGGYSSGSSSYGSGGRQSGSRGGSGGGGSISGGG 562

Query: 56  FGSRSLYGLGGSKRISIGGGSCAIS---GGYGSRAGGSYGFGGAGSGFGFGGGAGIGFGL 112
           +GS    G G   R   GGGS   S   GGYGS  G     GG+  G   GGG G G   
Sbjct: 563 YGS----GGGSGGRYGSGGGSKGGSISGGGYGSGGGKHSSGGGSRGGSSSGGGYGSG--- 615

Query: 113 GGGAGLAGGFGGPGF 127
           GGG+    G  G  F
Sbjct: 616 GGGSSSVKGSSGEAF 630



 Score = 63.5 bits (153), Expect = 5e-10
 Identities = 46/114 (40%), Positives = 56/114 (49%), Gaps = 15/114 (13%)

Query: 28  VSRSGFSSVSVSRSR--GSGGLGGACGGAGFGSRSLYGLGGSK---RISIGGGSCAISGG 82
           V+ S  SS   S++   GSGG G + GG      S YG GG +   R   GGG     GG
Sbjct: 503 VTSSTISSNVASKAAFGGSGGRGSSSGGGYSSGSSSYGSGGRQSGSRGGSGGGGSISGGG 562

Query: 83  YGSR--AGGSYGFGG-------AGSGFGFGGGA-GIGFGLGGGAGLAGGFGGPG 126
           YGS   +GG YG GG       +G G+G GGG    G G  GG+   GG+G  G
Sbjct: 563 YGSGGGSGGRYGSGGGSKGGSISGGGYGSGGGKHSSGGGSRGGSSSGGGYGSGG 616



 Score = 43.9 bits (102), Expect = 4e-04
 Identities = 39/103 (37%), Positives = 43/103 (41%), Gaps = 4/103 (3%)

Query: 10  SHSSSRRGFSANSARLPGVSRSGFSSVSVSRSRGSGGLGGACGGAGFGSRSLYGLGGSKR 69
           S+ S  R   +      G S SG    S   S G  G GG   G G  S   YG GG K 
Sbjct: 538 SYGSGGRQSGSRGGSGGGGSISGGGYGSGGGSGGRYGSGGGSKG-GSISGGGYGSGGGKH 596

Query: 70  ISIGG--GSCAISGGYGSRAGGSYGFGGAGSGFGFGGGAGIGF 110
            S GG  G  +  GGYGS  GGS    G+ SG  FG      F
Sbjct: 597 SSGGGSRGGSSSGGGYGSGGGGSSSVKGS-SGEAFGSSVTFSF 638


>gi|32567786 keratin 6L [Homo sapiens]
          Length = 535

 Score =  628 bits (1619), Expect = e-180
 Identities = 356/564 (63%), Positives = 414/564 (73%), Gaps = 37/564 (6%)

Query: 5   STTIRSHSSSRRGFSANSARLPGVS--RSGFSSVSVSRSRGSGGLGGACGGA--GFGSRS 60
           S+  R   S++ GFS+NSA     S  R+ FSSV+VSRS GSGG G  CG    GFGSRS
Sbjct: 3   SSVSRQTYSTKGGFSSNSASGGSGSQARTSFSSVTVSRSSGSGG-GAHCGPGTGGFGSRS 61

Query: 61  LYGLGGSKRISIGGGSCAISGGYGSRAGGSYGFGGAGSGFGFGGGAGIGFGLGGGAGLAG 120
           LY LGG K IS+            S AGG+   G A  GFGFG  A +G G G       
Sbjct: 62  LYNLGGHKSISV------------SVAGGAL-LGRALGGFGFGSRAFMGQGAGRQT---- 104

Query: 121 GFGGPGFPVCPPGGIQEVTVNQSLLTPLNLQIDPTIQRVRAEEREQIKTLNNKFASFIDK 180
            FG    P CPPGGIQEVTVNQSLLTPL+++IDP IQRVR +EREQIKTLNNKFASFIDK
Sbjct: 105 -FG----PACPPGGIQEVTVNQSLLTPLHVEIDPEIQRVRTQEREQIKTLNNKFASFIDK 159

Query: 181 VRFLEQQNKVLETKWTLLQEQGTK--TVRQNLEPLFEQYINNLRRQLDSIVGERGRLDSE 238
           VRFLEQQNKVLETKW LLQEQG      R NLEPLFE Y+ ++R  LD +  ERGRLDSE
Sbjct: 160 VRFLEQQNKVLETKWALLQEQGQNLGVTRNNLEPLFEAYLGSMRSTLDRLQSERGRLDSE 219

Query: 239 LRGMQDLVEDFKNKYEDEINKRTAAENEFVTLKKDVDAAYMNKVELQAKADTLTDEINFL 298
           LR +QDLVEDFKNKYEDEINK TAAENEFV LKKDVDAAYM +++L  K  TLT EI+FL
Sbjct: 220 LRNVQDLVEDFKNKYEDEINKHTAAENEFVVLKKDVDAAYMGRMDLHGKVGTLTQEIDFL 279

Query: 299 RALYDAELSQMQTHISDTSVVLSMDNNRNLDLDSIIAEVKAQYEEIAQRSRAEAESWYQT 358
           + LY+ ELSQ+QTH+S+T+VVLSMDNNRNLDLDSIIAEVKAQYE IAQRSRAEAE+WYQT
Sbjct: 280 QQLYEMELSQVQTHVSNTNVVLSMDNNRNLDLDSIIAEVKAQYELIAQRSRAEAEAWYQT 339

Query: 359 KYEELQVTAGRHGDDLRNTKQEIAEINRMIQRLRSEIDHVKKQCANLQAAIADAEQRGEM 418
           KYEELQVTAG+HGD+LR+TK EIAE+ R IQRL+ E D  KKQC  LQ AIA+AEQRGE+
Sbjct: 340 KYEELQVTAGKHGDNLRDTKNEIAELTRTIQRLQGEADAAKKQCQQLQTAIAEAEQRGEL 399

Query: 419 ALKDAKNKLEGLEDALQKAKQDLARLLKEYQELMNVKLALDVEIATYRKLLEGEECRLNG 478
           ALKDA+ KL  L+ AL +AK+DL RLL++YQELMNVKLALDVEIATYRKLLE EE R++G
Sbjct: 400 ALKDAQKKLGDLDVALHQAKEDLTRLLRDYQELMNVKLALDVEIATYRKLLESEESRMSG 459

Query: 479 EGVGQVNISVVQSTVSSGYGGASGVGSGLGLGGGSSYSYGSGLGVGGGFSSSSGRAIGGG 538
           E    V+ISV  ++ +   GGA+  G G+ LG       GSG    GGFS++ G +   G
Sbjct: 460 ECPSAVSISVTGNSTTVCGGGAASFGGGISLG-------GSGGATKGGFSTNVGYSTVKG 512

Query: 539 LSSVGGGSSTIKYTTTSSSSRKSY 562
              V  G+S ++ TTT  +S + Y
Sbjct: 513 -GPVSAGTSILRKTTTVKTSSQRY 535


>gi|194018511 keratin 77 [Homo sapiens]
          Length = 578

 Score =  589 bits (1519), Expect = e-168
 Identities = 329/565 (58%), Positives = 409/565 (72%), Gaps = 24/565 (4%)

Query: 12  SSSRRGFSANSARLPGVSRSGFSSVSVSRSRGSGGLGGACGGAGFGSRSLYGLGGSKRIS 71
           S SRR +S +S+   G       SV  +R R  GG G    G GFGSRSLY LGGS+ IS
Sbjct: 13  SMSRRVYSTSSSAGSGGGSPAVGSVCYARGRCGGG-GYGIHGRGFGSRSLYNLGGSRSIS 71

Query: 72  IGGGSCAISGGYGSRAGGSYGFGGAGSGFGFGGGAGIGFGLGGGAGLAG------GFGGP 125
           I     + SG    + GG  GFGG G GFG G     GFG GGG G AG      G GG 
Sbjct: 72  INLMGRSTSGF--CQGGGVGGFGG-GRGFGVGSTGAGGFG-GGGFGGAGFGTSNFGLGGF 127

Query: 126 GFPVCPPGGIQEVTVNQSLLTPLNLQIDPTIQRVRAEEREQIKTLNNKFASFIDKVRFLE 185
           G P CPPGGIQEVT+NQSLL PL+L++DP IQR++ +EREQI  LNNKFASFIDKVRFLE
Sbjct: 128 G-PYCPPGGIQEVTINQSLLEPLHLEVDPEIQRIKTQEREQIMVLNNKFASFIDKVRFLE 186

Query: 186 QQNKVLETKWTLLQEQGTKTVRQNLEPLFEQYINNLRRQLDSIVGERGRLDSELRGMQDL 245
           QQN+VL+TKW LLQ+  T T   NLEPL E YI +LRRQ+D +  E+ R ++E+R MQD+
Sbjct: 187 QQNQVLQTKWELLQQVNTSTGTNNLEPLLENYIGDLRRQVDLLSAEQMRQNAEVRSMQDV 246

Query: 246 VEDFKNKYEDEINKRTAAENEFVTLKKDVDAAYMNKVELQAKADTLTDEINFLRALYDAE 305
           VED+K+KYEDEINKRT +EN+FV LKKDVDAAY++KV+L+++ DTLT E+NFL+ L+  E
Sbjct: 247 VEDYKSKYEDEINKRTGSENDFVVLKKDVDAAYVSKVDLESRVDTLTGEVNFLKYLFLTE 306

Query: 306 LSQMQTHISDTSVVLSMDNNRNLDLDSIIAEVKAQYEEIAQRSRAEAESWYQTKYEELQV 365
           LSQ+QTHISDT+V+LSMDNNR+LDLDSII  V+ QYE IAQRS+ EAE+ YQTKY+ELQ+
Sbjct: 307 LSQVQTHISDTNVILSMDNNRSLDLDSIIDAVRTQYELIAQRSKDEAEALYQTKYQELQI 366

Query: 366 TAGRHGDDLRNTKQEIAEINRMIQRLRSEIDHVKKQCANLQAAIADAEQRGEMALKDAKN 425
           TAGRHGDDL+N+K EIAE+NR +QRL++EI +VKKQ   +Q+ I+DAE+RGE AL+DA  
Sbjct: 367 TAGRHGDDLKNSKMEIAELNRTVQRLQAEISNVKKQIEQMQSLISDAEERGEQALQDAWQ 426

Query: 426 KLEGLEDALQKAKQDLARLLKEYQELMNVKLALDVEIATYRKLLEGEECRLNGEGVGQVN 485
           KL+ LE+ALQ++K++LARLL++YQ ++ VKL+LDVEIATYR+LLEGEE R++GE    V+
Sbjct: 427 KLQDLEEALQQSKEELARLLRDYQAMLGVKLSLDVEIATYRQLLEGEESRMSGELQSHVS 486

Query: 486 ISVVQSTVS--------SGYG-GASGVGSGLGLGGGSSYSYGSGLG-VGGGFSSSSGRAI 535
           ISV  S VS          YG G  G GSG G GGG SY  G   G  GGG+ S  G   
Sbjct: 487 ISVQNSQVSVNGGAGGGGSYGSGGYGGGSGGGYGGGRSYRGGGARGRSGGGYGSGCGGGG 546

Query: 536 G--GGLSSVGGGSSTIKYTTTSSSS 558
           G  GG    G GSS ++   TS+++
Sbjct: 547 GSYGGSGRSGRGSSRVQIIQTSTNT 571


>gi|28173564 keratin 73 [Homo sapiens]
          Length = 540

 Score =  579 bits (1493), Expect = e-165
 Identities = 317/548 (57%), Positives = 401/548 (73%), Gaps = 38/548 (6%)

Query: 3   STSTTIRSHSSSRRGFSANSARLPGVSRSGFSSVSVSRSRGSGGLGGACGGAGFGSRSLY 62
           S   T +S ++++ GFS  SA L G S S + +       G  GL G     GF SRSLY
Sbjct: 2   SRQFTYKSGAAAKGGFSGCSAVLSGGSSSSYRA-------GGKGLSG-----GFSSRSLY 49

Query: 63  GLGGSKRISIGGGSCAISGGYGSRAGGSYGFG-GAGSGFGFGGGAGIGFGLGGGAGLAGG 121
            LGG++ IS    S       GS   G YGFG G  SGF     AG  FG      +A G
Sbjct: 50  SLGGARSISFNVAS-------GSGWAGGYGFGRGRASGF-----AGSMFG-----SVALG 92

Query: 122 FGGPGFPVCPPGGIQEVTVNQSLLTPLNLQIDPTIQRVRAEEREQIKTLNNKFASFIDKV 181
              P   +CPPGGI +VT+N+SLL PLN+++DP IQ+VRA+EREQIK LNNKFASFIDKV
Sbjct: 93  SVCPS--LCPPGGIHQVTINKSLLAPLNVELDPEIQKVRAQEREQIKVLNNKFASFIDKV 150

Query: 182 RFLEQQNKVLETKWTLLQEQGTKTVRQNLEPLFEQYINNLRRQLDSIVGERGRLDSELRG 241
           RFLEQQN+VLETKW LLQ+      + NLEP+ E YI+NLR+QL+++ G+R RLDSELR 
Sbjct: 151 RFLEQQNQVLETKWELLQQLDLNNCKNNLEPILEGYISNLRKQLETLSGDRVRLDSELRS 210

Query: 242 MQDLVEDFKNKYEDEINKRTAAENEFVTLKKDVDAAYMNKVELQAKADTLTDEINFLRAL 301
           ++++VED+K +YE+EINKRT AENEFV LKKDVDAAY +KVELQAK D L  EI F + L
Sbjct: 211 VREVVEDYKKRYEEEINKRTTAENEFVVLKKDVDAAYTSKVELQAKVDALDGEIKFFKCL 270

Query: 302 YDAELSQMQTHISDTSVVLSMDNNRNLDLDSIIAEVKAQYEEIAQRSRAEAESWYQTKYE 361
           Y+ E +Q+Q+HISDTS++LSMDNNRNLDLDSIIAEV+AQYEEIA++S+AEAE+ YQTK++
Sbjct: 271 YEGETAQIQSHISDTSIILSMDNNRNLDLDSIIAEVRAQYEEIARKSKAEAEALYQTKFQ 330

Query: 362 ELQVTAGRHGDDLRNTKQEIAEINRMIQRLRSEIDHVKKQCANLQAAIADAEQRGEMALK 421
           ELQ+ AGRHGDDL++TK EI+E+ R+IQRLRSEI+ VKKQCANL+ AIADAEQRG+ ALK
Sbjct: 331 ELQLAAGRHGDDLKHTKNEISELTRLIQRLRSEIESVKKQCANLETAIADAEQRGDCALK 390

Query: 422 DAKNKLEGLEDALQKAKQDLARLLKEYQELMNVKLALDVEIATYRKLLEGEECRLNGEGV 481
           DA+ KL+ LE ALQ+AK++LAR+L+EYQEL++VKL+LD+EIATYRKLLEGEECR++GE  
Sbjct: 391 DARAKLDELEGALQQAKEELARMLREYQELLSVKLSLDIEIATYRKLLEGEECRMSGEYT 450

Query: 482 GQVNISVVQSTVSSGYGGASGVGSGLGLGGGSSYSYGSGLGVGGGFSSSSGRAI-GGGLS 540
             V+ISV+ S+++    G +G G+G G     +Y Y     V GG+S   G  + G G  
Sbjct: 451 NSVSISVINSSMA----GMAGTGAGFGFSNAGTYGYWPS-SVSGGYSMLPGGCVTGSGNC 505

Query: 541 SVGGGSST 548
           S  G + T
Sbjct: 506 SPRGEART 513


>gi|15618995 keratin 71 [Homo sapiens]
          Length = 523

 Score =  568 bits (1465), Expect = e-162
 Identities = 313/550 (56%), Positives = 392/550 (71%), Gaps = 54/550 (9%)

Query: 3   STSTTIRSHSSSRRGFSANSARLPGVSRSGFSSVSVSRSRGSGGLGGACGGAGFGSRSLY 62
           S   T +S ++++ GFS  SA L G S S F +       GS GL G     GFGSRSLY
Sbjct: 2   SRQFTCKSGAAAKGGFSGCSAVLSGGSSSSFRA-------GSKGLSG-----GFGSRSLY 49

Query: 63  GLGGSKRISIGGGSCAISGGYGSRAGGSYGFGGAGSGFGFGGGAGIGFGLGGGAGLAGGF 122
            LGG + +++  GS   SGGY               GFG G  +G    + G   L    
Sbjct: 50  SLGGVRSLNVASGS-GKSGGY---------------GFGRGRASGFAGSMFGSVAL---- 89

Query: 123 GGPGFP-VCPPGGIQEVTVNQSLLTPLNLQIDPTIQRVRAEEREQIKTLNNKFASFIDKV 181
            GP  P VCPPGGI +VTVN+SLL PLN+++DP IQ+VRA+EREQIK LNNKFASFIDKV
Sbjct: 90  -GPVCPTVCPPGGIHQVTVNESLLAPLNVELDPEIQKVRAQEREQIKALNNKFASFIDKV 148

Query: 182 RFLEQQNKVLETKWTLLQEQGTKTVRQNLEPLFEQYINNLRRQLDSIVGERGRLDSELRG 241
           RFLEQQN+VLETKW LLQ+      + NLEP+ E YI+NLR+QL+++ G+R RLDSELR 
Sbjct: 149 RFLEQQNQVLETKWELLQQLDLNNCKNNLEPILEGYISNLRKQLETLSGDRVRLDSELRN 208

Query: 242 MQDLVEDFKNKYEDEINKRTAAENEFVTLKKDVDAAYMNKVELQAKADTLTDEINFLRAL 301
           ++D+VED+K +YE+EINKRTAAENEFV LKKDVDAAY NKVELQAK +++  EI F R L
Sbjct: 209 VRDVVEDYKKRYEEEINKRTAAENEFVLLKKDVDAAYANKVELQAKVESMDQEIKFFRCL 268

Query: 302 YDAELSQMQTHISDTSVVLSMDNNRNLDLDSIIAEVKAQYEEIAQRSRAEAESWYQTKYE 361
           ++AE++Q+Q+HISD SV+LSMDNNRNLDLDSII EV+ QYEEIA +S+AEAE+ YQTK++
Sbjct: 269 FEAEITQIQSHISDMSVILSMDNNRNLDLDSIIDEVRTQYEEIALKSKAEAEALYQTKFQ 328

Query: 362 ELQVTAGRHGDDLRNTKQEIAEINRMIQRLRSEIDHVKKQCANLQAAIADAEQRGEMALK 421
           ELQ+ AGRHGDDL+NTK EI+E+ R+IQR+RSEI++VKKQ +NL+ AIADAEQRG+ ALK
Sbjct: 329 ELQLAAGRHGDDLKNTKNEISELTRLIQRIRSEIENVKKQASNLETAIADAEQRGDNALK 388

Query: 422 DAKNKLEGLEDALQKAKQDLARLLKEYQELMNVKLALDVEIATYRKLLEGEECRLNGEGV 481
           DA+ KL+ LE AL +AK++LAR+L+EYQELM++KLALD+EIATYRKLLE EECR++GE  
Sbjct: 389 DARAKLDELEGALHQAKEELARMLREYQELMSLKLALDMEIATYRKLLESEECRMSGEFP 448

Query: 482 GQVNISVVQST------------VSSGY--------GGASGVGSGLGLGGGSSYSYGSGL 521
             V+IS++ ST            VS GY         G   V  G G   GS+  Y   L
Sbjct: 449 SPVSISIISSTSGGSVYGFRPSMVSGGYVANSSNCISGVCSVRGGEGRSRGSANDYKDTL 508

Query: 522 GVGGGFSSSS 531
           G G   S+ S
Sbjct: 509 GKGSSLSAPS 518



 Score = 32.7 bits (73), Expect = 0.91
 Identities = 20/50 (40%), Positives = 22/50 (44%)

Query: 494 SSGYGGASGVGSGLGLGGGSSYSYGSGLGVGGGFSSSSGRAIGGGLSSVG 543
           S G  G  G  S   LGG  S +  SG G  GG+    GRA G   S  G
Sbjct: 36  SKGLSGGFGSRSLYSLGGVRSLNVASGSGKSGGYGFGRGRASGFAGSMFG 85



 Score = 32.0 bits (71), Expect = 1.5
 Identities = 23/58 (39%), Positives = 31/58 (53%), Gaps = 7/58 (12%)

Query: 491 STVSSGYGGASGVGSGLGLGGGSSYSYGSGL-GVGGGFSSSSGRAIGGGLS-SVGGGS 546
           +    G+ G S V     L GGSS S+ +G  G+ GGF S S  ++GG  S +V  GS
Sbjct: 11  AAAKGGFSGCSAV-----LSGGSSSSFRAGSKGLSGGFGSRSLYSLGGVRSLNVASGS 63


>gi|28372503 keratin 72 isoform 1 [Homo sapiens]
          Length = 511

 Score =  567 bits (1462), Expect = e-162
 Identities = 314/538 (58%), Positives = 385/538 (71%), Gaps = 38/538 (7%)

Query: 19  SANSARLPGVSRSGFSSVSVSRSRGSGGLGGAC-----GGAGFGSRSLYGLGGSKRISIG 73
           S      P   R GFS  S   S G G    +      G A FGS+SL  LGGS+ +++ 
Sbjct: 2   SRQLTHFPRGERLGFSGCSAVLSGGIGSSSASFRARVKGSASFGSKSLSCLGGSRSLALS 61

Query: 74  GGSCAISGGYGSRAGGSYGFGGAGSGFGFGGGAGIGFGLGGGAGLAGGFGGPGFP-VCPP 132
             +         R GG  G G  G+ FG              AGL     GP  P VCPP
Sbjct: 62  AAA--------RRGGGRLG-GFVGTAFG-------------SAGL-----GPKCPSVCPP 94

Query: 133 GGIQEVTVNQSLLTPLNLQIDPTIQRVRAEEREQIKTLNNKFASFIDKVRFLEQQNKVLE 192
           GGI +VTVN+SLL PLN+++DP IQRVRA+EREQIK LNNKFASFIDKVRFLEQQN+VLE
Sbjct: 95  GGIPQVTVNKSLLAPLNVEMDPEIQRVRAQEREQIKALNNKFASFIDKVRFLEQQNQVLE 154

Query: 193 TKWTLLQEQGTKTVRQNLEPLFEQYINNLRRQLDSIVGERGRLDSELRGMQDLVEDFKNK 252
           TKW LLQ+      R+NLEP++E YI+NL++QL+ + G+  RLDSELR MQDLVED+K +
Sbjct: 155 TKWNLLQQLDLNNCRKNLEPIYEGYISNLQKQLEMLSGDGVRLDSELRNMQDLVEDYKKR 214

Query: 253 YEDEINKRTAAENEFVTLKKDVDAAYMNKVELQAKADTLTDEINFLRALYDAELSQMQTH 312
           YE EIN+RTAAENEFV LKKDVDAAYMNKVELQAK D+LTDEI F + LY+ E++Q+Q+H
Sbjct: 215 YEVEINRRTAAENEFVVLKKDVDAAYMNKVELQAKVDSLTDEIKFFKCLYEGEITQIQSH 274

Query: 313 ISDTSVVLSMDNNRNLDLDSIIAEVKAQYEEIAQRSRAEAESWYQTKYEELQVTAGRHGD 372
           ISDTS+VLSMDNNR+LDLDSIIAEV+AQYEEIA +S+AEAE+ YQTK +ELQVTAG+HGD
Sbjct: 275 ISDTSIVLSMDNNRDLDLDSIIAEVRAQYEEIALKSKAEAETLYQTKIQELQVTAGQHGD 334

Query: 373 DLRNTKQEIAEINRMIQRLRSEIDHVKKQCANLQAAIADAEQRGEMALKDAKNKLEGLED 432
           DL+ TK EI+E+NR+IQR+RSEI +VKKQCA+L+ AIADAEQRG+ ALKDA+ KL+ LE 
Sbjct: 335 DLKLTKAEISELNRLIQRIRSEIGNVKKQCADLETAIADAEQRGDCALKDARAKLDELEG 394

Query: 433 ALQKAKQDLARLLKEYQELMNVKLALDVEIATYRKLLEGEECRLNGEGVGQVNISVVQST 492
           AL +AK++LAR+L+EYQEL+++KLALD+EIATYRKLLE EECR++GE    V+ISV+ ST
Sbjct: 395 ALHQAKEELARMLREYQELVSLKLALDMEIATYRKLLESEECRMSGEYPNSVSISVISST 454

Query: 493 VSSGYGGASGVGSGLGLGGGSSYSYGSGLGVGGGFSSSSGRAIGGGLSSVGGGSSTIK 550
                 GA G G  +G G  SSYSY +          S G  +   L+   G S   K
Sbjct: 455 ----NAGAGGAGFSMGFGASSSYSYKTA-AADVKTKGSCGSELKDPLAKTSGSSCATK 507


>gi|226246663 keratin 72 isoform 1 [Homo sapiens]
          Length = 511

 Score =  567 bits (1462), Expect = e-162
 Identities = 314/538 (58%), Positives = 385/538 (71%), Gaps = 38/538 (7%)

Query: 19  SANSARLPGVSRSGFSSVSVSRSRGSGGLGGAC-----GGAGFGSRSLYGLGGSKRISIG 73
           S      P   R GFS  S   S G G    +      G A FGS+SL  LGGS+ +++ 
Sbjct: 2   SRQLTHFPRGERLGFSGCSAVLSGGIGSSSASFRARVKGSASFGSKSLSCLGGSRSLALS 61

Query: 74  GGSCAISGGYGSRAGGSYGFGGAGSGFGFGGGAGIGFGLGGGAGLAGGFGGPGFP-VCPP 132
             +         R GG  G G  G+ FG              AGL     GP  P VCPP
Sbjct: 62  AAA--------RRGGGRLG-GFVGTAFG-------------SAGL-----GPKCPSVCPP 94

Query: 133 GGIQEVTVNQSLLTPLNLQIDPTIQRVRAEEREQIKTLNNKFASFIDKVRFLEQQNKVLE 192
           GGI +VTVN+SLL PLN+++DP IQRVRA+EREQIK LNNKFASFIDKVRFLEQQN+VLE
Sbjct: 95  GGIPQVTVNKSLLAPLNVEMDPEIQRVRAQEREQIKALNNKFASFIDKVRFLEQQNQVLE 154

Query: 193 TKWTLLQEQGTKTVRQNLEPLFEQYINNLRRQLDSIVGERGRLDSELRGMQDLVEDFKNK 252
           TKW LLQ+      R+NLEP++E YI+NL++QL+ + G+  RLDSELR MQDLVED+K +
Sbjct: 155 TKWNLLQQLDLNNCRKNLEPIYEGYISNLQKQLEMLSGDGVRLDSELRNMQDLVEDYKKR 214

Query: 253 YEDEINKRTAAENEFVTLKKDVDAAYMNKVELQAKADTLTDEINFLRALYDAELSQMQTH 312
           YE EIN+RTAAENEFV LKKDVDAAYMNKVELQAK D+LTDEI F + LY+ E++Q+Q+H
Sbjct: 215 YEVEINRRTAAENEFVVLKKDVDAAYMNKVELQAKVDSLTDEIKFFKCLYEGEITQIQSH 274

Query: 313 ISDTSVVLSMDNNRNLDLDSIIAEVKAQYEEIAQRSRAEAESWYQTKYEELQVTAGRHGD 372
           ISDTS+VLSMDNNR+LDLDSIIAEV+AQYEEIA +S+AEAE+ YQTK +ELQVTAG+HGD
Sbjct: 275 ISDTSIVLSMDNNRDLDLDSIIAEVRAQYEEIALKSKAEAETLYQTKIQELQVTAGQHGD 334

Query: 373 DLRNTKQEIAEINRMIQRLRSEIDHVKKQCANLQAAIADAEQRGEMALKDAKNKLEGLED 432
           DL+ TK EI+E+NR+IQR+RSEI +VKKQCA+L+ AIADAEQRG+ ALKDA+ KL+ LE 
Sbjct: 335 DLKLTKAEISELNRLIQRIRSEIGNVKKQCADLETAIADAEQRGDCALKDARAKLDELEG 394

Query: 433 ALQKAKQDLARLLKEYQELMNVKLALDVEIATYRKLLEGEECRLNGEGVGQVNISVVQST 492
           AL +AK++LAR+L+EYQEL+++KLALD+EIATYRKLLE EECR++GE    V+ISV+ ST
Sbjct: 395 ALHQAKEELARMLREYQELVSLKLALDMEIATYRKLLESEECRMSGEYPNSVSISVISST 454

Query: 493 VSSGYGGASGVGSGLGLGGGSSYSYGSGLGVGGGFSSSSGRAIGGGLSSVGGGSSTIK 550
                 GA G G  +G G  SSYSY +          S G  +   L+   G S   K
Sbjct: 455 ----NAGAGGAGFSMGFGASSSYSYKTA-AADVKTKGSCGSELKDPLAKTSGSSCATK 507


>gi|148612803 keratin 6 irs4 [Homo sapiens]
          Length = 529

 Score =  560 bits (1442), Expect = e-159
 Identities = 317/554 (57%), Positives = 396/554 (71%), Gaps = 40/554 (7%)

Query: 12  SSSRRGFSANSARLPGVSRSGFSSVSVSRSRGSGGLGGACGGAGFGSRSLYGLGGSKRIS 71
           S  +  FS +SA +P   R    S++   + G G       GAGFGSRSLY LGG++RIS
Sbjct: 10  SGDKGNFSVHSAVVP---RKAVGSLASYCAAGRGA------GAGFGSRSLYSLGGNRRIS 60

Query: 72  I---GGGSCAISGGYGSRAGGSYGFGGAGSGFGFGGGAGIGFGLGGGAGLAGGFGGPGFP 128
               GGG  A  GGYG R G  YG GG  SGF     AG  FG       +   G     
Sbjct: 61  FNVAGGGVRA--GGYGFRPGSGYG-GGRASGF-----AGSMFG-------SVALGPACLS 105

Query: 129 VCPPGGIQEVTVNQSLLTPLNLQIDPTIQRVRAEEREQIKTLNNKFASFIDKVRFLEQQN 188
           VCPPGGI +VTVN+SLL PLN+++DP IQ+VRA+EREQIK LN+KFASFIDKVRFLEQQN
Sbjct: 106 VCPPGGIHQVTVNKSLLAPLNVELDPEIQKVRAQEREQIKVLNDKFASFIDKVRFLEQQN 165

Query: 189 KVLETKWTLLQEQGTKTVRQNLEPLFEQYINNLRRQLDSIVGERGRLDSELRGMQDLVED 248
           +VLETKW LLQ+      ++NLEP+ E YI+NLR+QL+++ G+R RLDSELR M+DLVED
Sbjct: 166 QVLETKWELLQQLDLNNCKKNLEPILEGYISNLRKQLETLSGDRVRLDSELRSMRDLVED 225

Query: 249 FKNKYEDEINKRTAAENEFVTLKKDVDAAYMNKVELQAKADTLTDEINFLRALYDAELSQ 308
           +K +YE EIN+RT AENEFV LKKD DAAY  KVELQAK D+L  EI FL+ LYDAE++Q
Sbjct: 226 YKKRYEVEINRRTTAENEFVVLKKDADAAYAVKVELQAKVDSLDKEIKFLKCLYDAEIAQ 285

Query: 309 MQTHISDTSVVLSMDNNRNLDLDSIIAEVKAQYEEIAQRSRAEAESWYQTKYEELQVTAG 368
           +QTH S+TSV+LSMDNNR+LDLDSIIAEV+  YEEIA +S+AEAE+ YQTK +ELQ+ A 
Sbjct: 286 IQTHASETSVILSMDNNRDLDLDSIIAEVRMHYEEIALKSKAEAEALYQTKIQELQLAAS 345

Query: 369 RHGDDLRNTKQEIAEINRMIQRLRSEIDHVKKQCANLQAAIADAEQRGEMALKDAKNKLE 428
           RHGDDL++T+ E+ E+NR+IQR+R EI +VKKQ A+L+ AIADAEQRG+ ALKDA+ KL+
Sbjct: 346 RHGDDLKHTRSEMVELNRLIQRIRCEIGNVKKQRASLETAIADAEQRGDNALKDAQAKLD 405

Query: 429 GLEDALQKAKQDLARLLKEYQELMNVKLALDVEIATYRKLLEGEECRLNGEGVGQVNISV 488
            LE AL +AK++LAR+L+EYQELM++KLALD+EIATYRKLLEGEECR++GE    V+ISV
Sbjct: 406 ELEGALHQAKEELARMLREYQELMSLKLALDMEIATYRKLLEGEECRMSGENPSSVSISV 465

Query: 489 V-QSTVSSGYGGASGVGSGLGLGGGSSYSYGSGLGVGGGFSSSSGRAIGGGLSSVGGGSS 547
           +  S+ S  +  ++GV  G     GSS S  SG        + +  A GG L    G   
Sbjct: 466 ISSSSYSYHHPSSAGVDLGASAVAGSSGSTQSG-------QTKTTEARGGDLKDTQG--- 515

Query: 548 TIKYTTTSSSSRKS 561
             K T  S  +RK+
Sbjct: 516 --KSTPASIPARKA 527


>gi|15431316 keratin, hair, basic, 4 [Homo sapiens]
          Length = 600

 Score =  525 bits (1351), Expect = e-149
 Identities = 313/605 (51%), Positives = 388/605 (64%), Gaps = 62/605 (10%)

Query: 9   RSHSSSRRG-FSANSARLP-GVSRSGFSSVSVSRSRGSGGLGGACGGAGFGSRSLYGLGG 66
           R  S  R G FS+ SA  P  ++R   +SVS     G  GLG       FGSRS+   G 
Sbjct: 7   RVSSGHRVGNFSSCSAMTPQNLNRFRANSVSCWSGPGFRGLGS------FGSRSVITFGS 60

Query: 67  SKRISIGGGSCAISGGYGSRAGGSYGFG-GAGSGFGFGGGAGIGFGLGGGAGLAGGFGGP 125
                   GS  I  G    AG   GFG G G G G    + +G G G G+G+  GFGGP
Sbjct: 61  YSPRIAAVGSRPIHCGVRFGAGCGMGFGDGRGVGLGPRADSCVGLGFGAGSGIGYGFGGP 120

Query: 126 GF---------PVCPPGGIQEVTVNQSLLTPLNLQIDPTIQRVRAEEREQIKTLNNKFAS 176
           GF         P  P   I  VTVN+SLLTPLNL+IDP  QRV+ +E+EQIKTLNNKFAS
Sbjct: 121 GFGYRVGGVGVPAAP--SITAVTVNKSLLTPLNLEIDPNAQRVKKDEKEQIKTLNNKFAS 178

Query: 177 FIDKVRFLEQQNKVLETKWTLLQEQGTKTVRQNLEPLFEQYINNLRRQLDSIVGERGRLD 236
           FIDKVRFLEQQNK+LETKW+ LQEQ  K +R NLEPLFE YI NLRRQL+ +V ++ RL 
Sbjct: 179 FIDKVRFLEQQNKLLETKWSFLQEQ--KCIRSNLEPLFESYITNLRRQLEVLVSDQARLQ 236

Query: 237 SELRGMQDLVEDFKNKYEDEINKRTAAENEFVTLKKDVDAAYMNKVELQAKADTLTDEIN 296
           +E   +QD++E FK KYE+E+  R  AENEFV LKKDVDAA+MNK +L+A  DTLT EI+
Sbjct: 237 AERNHLQDVLEGFKKKYEEEVVCRANAENEFVALKKDVDAAFMNKSDLEANVDTLTQEID 296

Query: 297 FLRALYDAELSQMQTHISDTSVVLSMDNNRNLDLDSIIAEVKAQYEEIAQRSRAEAESWY 356
           FL+ LY  E+  +Q+HIS+TSV++ MDN+R+L+LD IIAEVKAQYEE+A+RSRA+AE+WY
Sbjct: 297 FLKTLYMEEIQLLQSHISETSVIVKMDNSRDLNLDGIIAEVKAQYEEVARRSRADAEAWY 356

Query: 357 QTKYEELQVTAGRHGDDLRNTKQEIAEINRMIQRLRSEIDHVKKQCANLQAAIADAEQRG 416
           QTKYEE+QVTAG+H D+LRN + EI E+ R+IQRL++EI+H K Q A L+AA+A+AEQ+G
Sbjct: 357 QTKYEEMQVTAGQHCDNLRNIRNEINELTRLIQRLKAEIEHAKAQRAKLEAAVAEAEQQG 416

Query: 417 EMALKDAKNKLEGLEDALQKAKQDLARLLKEYQELMNVKLALDVEIATYRKLLEGEECRL 476
           E  L DAK KL  LE ALQ+AKQD+AR L EYQELMN KL LD+EIATYR+LLEGEE RL
Sbjct: 417 EATLSDAKCKLADLECALQQAKQDMARQLCEYQELMNAKLGLDIEIATYRRLLEGEESRL 476

Query: 477 NGEGVGQVNISVVQSTVSSGYGGASGVGSGLGLGGGSSYSYGSGLGVGGGFSSSSGRAIG 536
             EGVG VNISV  S      G    V       GG ++S  S +    G  +S G ++G
Sbjct: 477 -CEGVGPVNISVSSSRGGLVCGPEPLVAGSTLSRGGVTFSGSSSVCATSGVLASCGPSLG 535

Query: 537 --------------------------------------GGLSSVGGG-SSTIKYTTTSSS 557
                                                 GG SS  GG SS++++ +T++S
Sbjct: 536 GARVAPATGDLLSTGTRSGSMLISEACVPSVPCPLPTQGGFSSCSGGRSSSVRFVSTTTS 595

Query: 558 SRKSY 562
            R  Y
Sbjct: 596 CRTKY 600


>gi|4504919 keratin 8 [Homo sapiens]
          Length = 483

 Score =  523 bits (1346), Expect = e-148
 Identities = 293/473 (61%), Positives = 347/473 (73%), Gaps = 24/473 (5%)

Query: 67  SKRISIGGGSCAISGGYGSRAGGSYGFGGAGSGFGFGGGAGIGFGLGGGAGLAGGFGGPG 126
           S ++S  G     S  Y S  G       + S F   G +    GLGGG G A G GG  
Sbjct: 9   SYKVSTSGPRAFSSRSYTSGPGSRI----SSSSFSRVGSSNFRGGLGGGYGGASGMGG-- 62

Query: 127 FPVCPPGGIQEVTVNQSLLTPLNLQIDPTIQRVRAEEREQIKTLNNKFASFIDKVRFLEQ 186
                   I  VTVNQSLL+PL L++DP IQ VR +E+EQIKTLNNKFASFIDKVRFLEQ
Sbjct: 63  --------ITAVTVNQSLLSPLVLEVDPNIQAVRTQEKEQIKTLNNKFASFIDKVRFLEQ 114

Query: 187 QNKVLETKWTLLQEQGTKTVRQNLEPLFEQYINNLRRQLDSIVGERGRLDSELRGMQDLV 246
           QNK+LETKW+LLQ+Q  KT R N++ +FE YINNLRRQL+++  E+ +L++EL  MQ LV
Sbjct: 115 QNKMLETKWSLLQQQ--KTARSNMDNMFESYINNLRRQLETLGQEKLKLEAELGNMQGLV 172

Query: 247 EDFKNKYEDEINKRTAAENEFVTLKKDVDAAYMNKVELQAKADTLTDEINFLRALYDAEL 306
           EDFKNKYEDEINKRT  ENEFV +KKDVD AYMNKVEL+++ + LTDEINFLR LY+ E+
Sbjct: 173 EDFKNKYEDEINKRTEMENEFVLIKKDVDEAYMNKVELESRLEGLTDEINFLRQLYEEEI 232

Query: 307 SQMQTHISDTSVVLSMDNNRNLDLDSIIAEVKAQYEEIAQRSRAEAESWYQTKYEELQVT 366
            ++Q+ ISDTSVVLSMDN+R+LD+DSIIAEVKAQYE+IA RSRAEAES YQ KYEELQ  
Sbjct: 233 RELQSQISDTSVVLSMDNSRSLDMDSIIAEVKAQYEDIANRSRAEAESMYQIKYEELQSL 292

Query: 367 AGRHGDDLRNTKQEIAEINRMIQRLRSEIDHVKKQCANLQAAIADAEQRGEMALKDAKNK 426
           AG+HGDDLR TK EI+E+NR I RL++EI+ +K Q A+L+AAIADAEQRGE+A+KDA  K
Sbjct: 293 AGKHGDDLRRTKTEISEMNRNISRLQAEIEGLKGQRASLEAAIADAEQRGELAIKDANAK 352

Query: 427 LEGLEDALQKAKQDLARLLKEYQELMNVKLALDVEIATYRKLLEGEECRLNGEGVGQVNI 486
           L  LE ALQ+AKQD+AR L+EYQELMNVKLALD+EIATYRKLLEGEE RL     G  N+
Sbjct: 353 LSELEAALQRAKQDMARQLREYQELMNVKLALDIEIATYRKLLEGEESRLES---GMQNM 409

Query: 487 SVVQSTVSSGYGGASGVGSGLGLGGGSSYSYGSGLGVGGGFSS----SSGRAI 535
           S+   T S   GG S    GL    G SYS GS  G G G SS    SS RA+
Sbjct: 410 SIHTKTTSGYAGGLSSAYGGL-TSPGLSYSLGSSFGSGAGSSSFSRTSSSRAV 461



 Score = 32.0 bits (71), Expect = 1.5
 Identities = 26/72 (36%), Positives = 35/72 (48%), Gaps = 12/72 (16%)

Query: 4  TSTTIRSHSSSRRGFSANSARL-PG--VSRSGFSSVSVSRSRGSGGLGGACGGAGFGSRS 60
          T  + +  +S  R FS+ S    PG  +S S FS V  S  RG  GLGG  GGA      
Sbjct: 6  TQKSYKVSTSGPRAFSSRSYTSGPGSRISSSSFSRVGSSNFRG--GLGGGYGGAS----- 58

Query: 61 LYGLGGSKRISI 72
            G+GG   +++
Sbjct: 59 --GMGGITAVTV 68


>gi|67782365 keratin 7 [Homo sapiens]
          Length = 469

 Score =  519 bits (1337), Expect = e-147
 Identities = 285/449 (63%), Positives = 339/449 (75%), Gaps = 12/449 (2%)

Query: 76  SCAISGGYGSRAGGSYGFGGAGSGFGFGGGAGIGFGLGGGAGLAGGFGGPGFPVCPPGGI 135
           S A SG        S   GG GS   +G GA           +   +GGP        GI
Sbjct: 14  SAAFSGRGAQVRLSSARPGGLGSSSLYGLGAS-----RPRVAVRSAYGGP-----VGAGI 63

Query: 136 QEVTVNQSLLTPLNLQIDPTIQRVRAEEREQIKTLNNKFASFIDKVRFLEQQNKVLETKW 195
           +EVT+NQSLL PL L  DP++QRVR EE EQIKTLNNKFASFIDKVRFLEQQNK+LETKW
Sbjct: 64  REVTINQSLLAPLRLDADPSLQRVRQEESEQIKTLNNKFASFIDKVRFLEQQNKLLETKW 123

Query: 196 TLLQEQGTKTVRQNLEPLFEQYINNLRRQLDSIVGERGRLDSELRGMQDLVEDFKNKYED 255
           TLLQEQ +      L  +FE  I  LR QL+++  + GRL++ELR MQD+VEDFKNKYED
Sbjct: 124 TLLQEQKSAK-SSRLPDIFEAQIAGLRGQLEALQVDGGRLEAELRSMQDVVEDFKNKYED 182

Query: 256 EINKRTAAENEFVTLKKDVDAAYMNKVELQAKADTLTDEINFLRALYDAELSQMQTHISD 315
           EIN RTAAENEFV LKKDVDAAYM+KVEL+AK D L DEINFLR L + EL+++Q+ ISD
Sbjct: 183 EINHRTAAENEFVVLKKDVDAAYMSKVELEAKVDALNDEINFLRTLNETELTELQSQISD 242

Query: 316 TSVVLSMDNNRNLDLDSIIAEVKAQYEEIAQRSRAEAESWYQTKYEELQVTAGRHGDDLR 375
           TSVVLSMDN+R+LDLD IIAEVKAQYEE+A+ SRAEAE+WYQTK+E LQ  AG+HGDDLR
Sbjct: 243 TSVVLSMDNSRSLDLDGIIAEVKAQYEEMAKCSRAEAEAWYQTKFETLQAQAGKHGDDLR 302

Query: 376 NTKQEIAEINRMIQRLRSEIDHVKKQCANLQAAIADAEQRGEMALKDAKNKLEGLEDALQ 435
           NT+ EI+E+NR IQRL++EID++K Q A L+AAIA+AE+RGE+ALKDA+ K E LE ALQ
Sbjct: 303 NTRNEISEMNRAIQRLQAEIDNIKNQRAKLEAAIAEAEERGELALKDARAKQEELEAALQ 362

Query: 436 KAKQDLARLLKEYQELMNVKLALDVEIATYRKLLEGEECRLNGEGVGQVNISVVQSTVSS 495
           + KQD+AR L+EYQELM+VKLALD+EIATYRKLLEGEE RL G+GVG VNISV+ ST  S
Sbjct: 363 RGKQDMARQLREYQELMSVKLALDIEIATYRKLLEGEESRLAGDGVGAVNISVMNSTGGS 422

Query: 496 GYGGASGVGSGLGLGGGSSYSYGSGLGVG 524
             GG  G+  G G  G ++ S+ S  G G
Sbjct: 423 SSGGGIGLTLG-GTMGSNALSFSSSAGPG 450


>gi|89357932 keratin 5b [Homo sapiens]
          Length = 520

 Score =  492 bits (1266), Expect = e-139
 Identities = 286/561 (50%), Positives = 369/561 (65%), Gaps = 64/561 (11%)

Query: 14  SRRGFSANSA---RLPGVSRSGFSSVSVSRSRGSGGLGGACGGAGFGSRSLYGLGGSKRI 70
           ++RGFSA SA   R  G SR GFSS      RG           GF SRSL   GG    
Sbjct: 8   AQRGFSARSACSARSRGRSRGGFSS------RG-----------GFSSRSLNSFGGCLE- 49

Query: 71  SIGGGSCAISGGYGSRAGGSYGFGGAGSGFGFGGGAGIGFGLGGGAGLAGGFGGPGFPVC 130
                                  G  GS +G GG  G+ FG   G        GPG  +C
Sbjct: 50  -----------------------GSRGSTWGSGGRLGVRFGEWSG--------GPGLSLC 78

Query: 131 PPGGIQEVTVNQSLLTPLNLQIDPTIQRVRAEEREQIKTLNNKFASFIDKVRFLEQQNKV 190
           PPGGIQEVT+NQ+LLTPL ++IDP  Q VR +E ++I+TLNN+FASFIDKVRFLEQQNKV
Sbjct: 79  PPGGIQEVTINQNLLTPLKIEIDPQFQVVRTQETQEIRTLNNQFASFIDKVRFLEQQNKV 138

Query: 191 LETKWTLLQEQGTKTVRQNLEPLFEQYINNLRRQLDSIVGERGRLDSELRGMQDLVEDFK 250
           LETKW LLQ+QG    +Q LEP+FE  ++ LR+QL+ + GERG LD+EL+  +D  E++K
Sbjct: 139 LETKWHLLQQQGLSGSQQGLEPVFEACLDQLRKQLEQLQGERGALDAELKACRDQEEEYK 198

Query: 251 NKYEDEINKRTAAENEFVTLKKDVDAAYMNKVELQAKADTLTDEINFLRALYDAELSQMQ 310
           +KYE+E ++R   EN+FV LKKDVD  +++K+EL+ K + L + + FL+ L + EL Q+Q
Sbjct: 199 SKYEEEAHRRATLENDFVVLKKDVDGVFLSKMELEGKLEALREYLYFLKHLNEEELGQLQ 258

Query: 311 THISDTSVVLSMDNNRNLDLDSIIAEVKAQYEEIAQRSRAEAESWYQTKYEELQVTAGRH 370
           T  SDTSVVLSMDNNR LD  SII EV+A+YEEIA+ S+AEAE+ YQTKY+ELQV+A  H
Sbjct: 259 TQASDTSVVLSMDNNRYLDFSSIITEVRARYEEIARSSKAEAEALYQTKYQELQVSAQLH 318

Query: 371 GDDLRNTKQEIAEINRMIQRLRSEIDHVKKQCANLQAAIADAEQRGEMALKDAKNKLEGL 430
           GD ++ TK +I+++++ IQRL+S+ +++KKQ A+LQAAI DAEQRGE+ALKDA+ K++ L
Sbjct: 319 GDRMQETKVQISQLHQEIQRLQSQTENLKKQNASLQAAITDAEQRGELALKDAQAKVDEL 378

Query: 431 EDALQKAKQDLARLLKEYQELMNVKLALDVEIATYRKLLEGEECRLNGEGVGQVNISVV- 489
           E AL+ AKQ+LARLL EYQEL + KL+LDVEIATYR+LLEGEECR++GE   QV IS V 
Sbjct: 379 EAALRMAKQNLARLLCEYQELTSTKLSLDVEIATYRRLLEGEECRMSGECTSQVTISSVG 438

Query: 490 -QSTVSSGYGGASGVGSGLGLGGGSSYSYGSGLGVGG-GFSSSSGR-------AIGGGLS 540
             + +S G GG  G   GLG G GS  S  + +  GG      SG+       ++ G  S
Sbjct: 439 GSAVMSGGVGGGLGSTCGLGSGKGSPGSCCTSIVTGGSNIILGSGKDPVLDSCSVSG--S 496

Query: 541 SVGGGSSTIKYTTTSSSSRKS 561
           S G    TI   T  SS + S
Sbjct: 497 SAGSSCHTILKKTVESSLKTS 517


>gi|226246665 keratin 72 isoform 2 [Homo sapiens]
          Length = 469

 Score =  487 bits (1253), Expect = e-137
 Identities = 284/538 (52%), Positives = 347/538 (64%), Gaps = 80/538 (14%)

Query: 19  SANSARLPGVSRSGFSSVSVSRSRGSGGLGGAC-----GGAGFGSRSLYGLGGSKRISIG 73
           S      P   R GFS  S   S G G    +      G A FGS+SL  LGGS+ +++ 
Sbjct: 2   SRQLTHFPRGERLGFSGCSAVLSGGIGSSSASFRARVKGSASFGSKSLSCLGGSRSLALS 61

Query: 74  GGSCAISGGYGSRAGGSYGFGGAGSGFGFGGGAGIGFGLGGGAGLAGGFGGPGFP-VCPP 132
             +         R GG  G G  G+ FG              AGL     GP  P VCPP
Sbjct: 62  AAA--------RRGGGRLG-GFVGTAFG-------------SAGL-----GPKCPSVCPP 94

Query: 133 GGIQEVTVNQSLLTPLNLQIDPTIQRVRAEEREQIKTLNNKFASFIDKVRFLEQQNKVLE 192
           GGI +VTVN+SLL PLN+++DP IQRVRA+EREQIK LNNKFASFIDKVRFLEQQN+VLE
Sbjct: 95  GGIPQVTVNKSLLAPLNVEMDPEIQRVRAQEREQIKALNNKFASFIDKVRFLEQQNQVLE 154

Query: 193 TKWTLLQEQGTKTVRQNLEPLFEQYINNLRRQLDSIVGERGRLDSELRGMQDLVEDFKNK 252
           TKW LLQ+      R+NLEP++E YI+NL++QL+ + G+  RLDSELR MQDLVED+K +
Sbjct: 155 TKWNLLQQLDLNNCRKNLEPIYEGYISNLQKQLEMLSGDGVRLDSELRNMQDLVEDYKKR 214

Query: 253 YEDEINKRTAAENEFVTLKKDVDAAYMNKVELQAKADTLTDEINFLRALYDAELSQMQTH 312
           YE EIN+RTAAENEFV LKKDVDAAYMNKVELQAK D+LTDEI F + LY+ E++Q+Q+H
Sbjct: 215 YEVEINRRTAAENEFVVLKKDVDAAYMNKVELQAKVDSLTDEIKFFKCLYEGEITQIQSH 274

Query: 313 ISDTSVVLSMDNNRNLDLDSIIAEVKAQYEEIAQRSRAEAESWYQTKYEELQVTAGRHGD 372
           ISDTS+VLSMDNNR+LDLDSIIAEV+AQYEEIA +S+AEAE+ YQTK             
Sbjct: 275 ISDTSIVLSMDNNRDLDLDSIIAEVRAQYEEIALKSKAEAETLYQTK------------- 321

Query: 373 DLRNTKQEIAEINRMIQRLRSEIDHVKKQCANLQAAIADAEQRGEMALKDAKNKLEGLED 432
                                        CA+L+ AIADAEQRG+ ALKDA+ KL+ LE 
Sbjct: 322 -----------------------------CADLETAIADAEQRGDCALKDARAKLDELEG 352

Query: 433 ALQKAKQDLARLLKEYQELMNVKLALDVEIATYRKLLEGEECRLNGEGVGQVNISVVQST 492
           AL +AK++LAR+L+EYQEL+++KLALD+EIATYRKLLE EECR++GE    V+ISV+ ST
Sbjct: 353 ALHQAKEELARMLREYQELVSLKLALDMEIATYRKLLESEECRMSGEYPNSVSISVISST 412

Query: 493 VSSGYGGASGVGSGLGLGGGSSYSYGSGLGVGGGFSSSSGRAIGGGLSSVGGGSSTIK 550
                 GA G G  +G G  SSYSY +          S G  +   L+   G S   K
Sbjct: 413 ----NAGAGGAGFSMGFGASSSYSYKTA-AADVKTKGSCGSELKDPLAKTSGSSCATK 465


>gi|27477127 keratin 82 [Homo sapiens]
          Length = 513

 Score =  452 bits (1162), Expect = e-127
 Identities = 262/523 (50%), Positives = 339/523 (64%), Gaps = 24/523 (4%)

Query: 48  GGACGGAGFGSRSLYGLGGSKRISIGGGSCAISGGYGSRAGGSYGFGGAGSGFGFGGGAG 107
           G  CG   F S S          ++  G C   GG G RA G  G               
Sbjct: 9   GSRCGSQSFSSYSAVMPRMVTHYAVSKGPCRPGGGRGLRALGCLGSRSL---------CN 59

Query: 108 IGFGLGGGAGLAGGFGGPGF-----PVCPPGG-IQEVTVNQSLLTPLNLQIDPTIQRVRA 161
           +GFG    A   GG   PGF       C P   I  VT+N+SLL PL L+IDPT+QRV+ 
Sbjct: 60  VGFGRPRVASRCGGTL-PGFGYRLGATCGPSACITPVTINESLLVPLALEIDPTVQRVKR 118

Query: 162 EEREQIKTLNNKFASFIDKVRFLEQQNKVLETKWTLLQEQGTKTVRQNLEPLFEQYINNL 221
           +E+EQIK LNN+FASFI+KVRFLEQ+NK+LETKW  +Q+Q  +  + N+EP+FE YI+ L
Sbjct: 119 DEKEQIKCLNNRFASFINKVRFLEQKNKLLETKWNFMQQQ--RCCQTNIEPIFEGYISAL 176

Query: 222 RRQLDSIVGERGRLDSELRGMQDLVEDFKNKYEDEINKRTAAENEFVTLKKDVDAAYMNK 281
           RRQLD + G+R RL+SEL  +Q  +E +K KYE+E++ R   ENEFV LKKDVD A++ K
Sbjct: 177 RRQLDCVSGDRVRLESELCSLQAALEGYKKKYEEELSLRPCVENEFVALKKDVDTAFLMK 236

Query: 282 VELQAKADTLTDEINFLRALYDAELSQMQTHISDTSVVLSMDNNRNLDLDSIIAEVKAQY 341
            +L+  A+ L  EI+FL++LY+ E+  +Q+ IS+TSV++ MDN+R LD+D IIAE+KAQY
Sbjct: 237 ADLETNAEALVQEIDFLKSLYEEEICLLQSQISETSVIVKMDNSRELDVDGIIAEIKAQY 296

Query: 342 EEIAQRSRAEAESWYQTKYEELQVTAGRHGDDLRNTKQEIAEINRMIQRLRSEIDHVKKQ 401
           ++IA RS+AEAE+WYQ +YEEL+VTAG H D+LRN K EI E+N++IQRL+ E ++VK Q
Sbjct: 297 DDIASRSKAEAEAWYQCRYEELRVTAGNHCDNLRNRKNEILEMNKLIQRLQQETENVKAQ 356

Query: 402 CANLQAAIADAEQRGEMALKDAKNKLEGLEDALQKAKQDLARLLKEYQELMNVKLALDVE 461
              L+ AIA+AEQ+GE AL DAK KL GLE+ALQKAKQD+A LLKEYQE+MN KL LD+E
Sbjct: 357 RCKLEGAIAEAEQQGEAALNDAKCKLAGLEEALQKAKQDMACLLKEYQEVMNSKLGLDIE 416

Query: 462 IATYRKLLEGEECRLNGEGVGQVNISVVQSTVSSGYGGASGVGSGLGLGGGSSYSYGSGL 521
           IATYR+LLEGEE RL  EG+G VNISV  S  +  Y         L  G   S    S +
Sbjct: 417 IATYRRLLEGEEHRL-CEGIGPVNISVSSSKGAFLYEPCGVSTPVLSTGVLRSNGGCSIV 475

Query: 522 GVGGGFSSSSGRAIGGGLSSVGGGSSTIKYTTTSSSSRKSYKH 564
           G G  +     +    GL S G G  +   T  +  S  S+KH
Sbjct: 476 GTGELYVPCEPQ----GLLSCGSGRKS-SMTLGAGGSSPSHKH 513


>gi|4504935 keratin 85 [Homo sapiens]
          Length = 507

 Score =  449 bits (1156), Expect = e-126
 Identities = 273/553 (49%), Positives = 346/553 (62%), Gaps = 76/553 (13%)

Query: 1   MASTSTTIRSHSSSRRGFSANSARLPGVSRSGFSSVSVSRSRGSGGLGGACGGAGFGSRS 60
           M+  S  I S     R FS+ SA  P        S +  R     G+    G  GFGSRS
Sbjct: 1   MSCRSYRISSGCGVTRNFSSCSAVAPKTGNRCCISAAPYR-----GVSCYRGLTGFGSRS 55

Query: 61  LYGLGG-SKRISIGG---GSCAISGGYGSRAGGSYGFGGAGSGFGFGGGAGIGFGLGGGA 116
           L  LG    RI++GG   GSC  S GY S                               
Sbjct: 56  LCNLGSCGPRIAVGGFRAGSCGRSFGYRS------------------------------- 84

Query: 117 GLAGGFGGPGFPVCPPGGIQEVTVNQSLLTPLNLQIDPTIQRVRAEEREQIKTLNNKFAS 176
              GG  GP  P C    I  V+VN+SLLTPLNL+IDP  Q V+ EE+EQIK+LN++FA+
Sbjct: 85  ---GGVCGPS-PPC----ITTVSVNESLLTPLNLEIDPNAQCVKQEEKEQIKSLNSRFAA 136

Query: 177 FIDKVRFLEQQNKVLETKWTLLQEQGTKTVRQNLEPLFEQYINNLRRQLDSIVGERGRLD 236
           FIDKVRFLEQQNK+LETKW   Q Q  +    NLEPLF  YI  LRR+ + +  + GRL 
Sbjct: 137 FIDKVRFLEQQNKLLETKWQFYQNQ--RCCESNLEPLFSGYIETLRREAECVEADSGRLA 194

Query: 237 SELRGMQDLVEDFKNKYEDEINKRTAAENEFVTLKKDVDAAYMNKVELQAKADTLTDEIN 296
           SEL  +Q+++E +K KYE+E+  R  AENEFV LKKDVD AY+ K +L+A  + L +E +
Sbjct: 195 SELNHVQEVLEGYKKKYEEEVALRATAENEFVVLKKDVDCAYLRKSDLEANVEALVEESS 254

Query: 297 FLRALYDAELSQMQTHISDTSVVLSMDNNRNLDLDSIIAEVKAQYEEIAQRSRAEAESWY 356
           FLR LY+ E+  +Q HISDTSV++ MDN+R+L++D IIAE+KAQY+++A RSRAEAESWY
Sbjct: 255 FLRRLYEEEIRVLQAHISDTSVIVKMDNSRDLNMDCIIAEIKAQYDDVASRSRAEAESWY 314

Query: 357 QTKYEELQVTAGRHGDDLRNTKQEIAEINRMIQRLRSEIDHVKKQCANLQAAIADAEQRG 416
           ++K EE++ T  RHG+ LR TK+EI E+NRMIQRL +EI++ K Q A L+AA+A+AEQ+G
Sbjct: 315 RSKCEEMKATVIRHGETLRRTKEEINELNRMIQRLTAEIENAKCQRAKLEAAVAEAEQQG 374

Query: 417 EMALKDAKNKLEGLEDALQKAKQDLARLLKEYQELMNVKLALDVEIATYRKLLEGEECRL 476
           E AL DA+ KL  LE ALQKAKQD+A LLKEYQE+MN KL LD+EIATYR+LLEGEE RL
Sbjct: 375 EAALSDARCKLAELEGALQKAKQDMACLLKEYQEVMNSKLGLDIEIATYRRLLEGEEHRL 434

Query: 477 NGEGVGQVNISVVQSTVSSGYGGASGVGSGLGLGGGSSYSYGSGLGVGGGFSSSSGRAIG 536
             EGVG VN+      VSS  GG S         GG SY            S++ GR I 
Sbjct: 435 -CEGVGSVNV-----CVSSSRGGVS--------CGGLSY------------STTPGRQIT 468

Query: 537 GGLSSVGGGSSTI 549
            G S++GG  + +
Sbjct: 469 SGPSAIGGSITVV 481


>gi|169790853 keratin, hair, basic, 1 [Homo sapiens]
          Length = 505

 Score =  433 bits (1113), Expect = e-121
 Identities = 258/520 (49%), Positives = 337/520 (64%), Gaps = 31/520 (5%)

Query: 53  GAGFGSRSLYGLGGSKRISIGG---GSCAISG----GYGSRAGGSYGFGGAGSGFGF-GG 104
           G+GFG R+         IS  G   G C I+     G     G + GFG      GF  G
Sbjct: 4   GSGFGGRAF------SCISACGPRPGRCCITAAPYRGISCYRGLTGGFGSHSVCGGFRAG 57

Query: 105 GAGIGFGLGGGAGLAGGFGGPGFPVCPPGGIQEVTVNQSLLTPLNLQIDPTIQRVRAEER 164
             G  FG       +GG  GP  P C    I  V+VN+SLLTPLNL+IDP  Q V+ EE+
Sbjct: 58  SCGRSFGYR-----SGGVCGPS-PPC----ITTVSVNESLLTPLNLEIDPNAQCVKQEEK 107

Query: 165 EQIKTLNNKFASFIDKVRFLEQQNKVLETKWTLLQEQGTKTVRQNLEPLFEQYINNLRRQ 224
           EQIK+LN++FA+FIDKVRFLEQQNK+LETK    Q +  +  + NLEPLFE YI  LRR+
Sbjct: 108 EQIKSLNSRFAAFIDKVRFLEQQNKLLETKLQFYQNR--ECCQSNLEPLFEGYIETLRRE 165

Query: 225 LDSIVGERGRLDSELRGMQDLVEDFKNKYEDEINKRTAAENEFVTLKKDVDAAYMNKVEL 284
            + +  + GRL SEL  +Q+++E +K KYE+E++ R  AENEFV LKKDVD AY+ K +L
Sbjct: 166 AECVEADSGRLASELNHVQEVLEGYKKKYEEEVSLRATAENEFVALKKDVDCAYLRKSDL 225

Query: 285 QAKADTLTDEINFLRALYDAELSQMQTHISDTSVVLSMDNNRNLDLDSIIAEVKAQYEEI 344
           +A  + L  EI+FLR LY+ E+  +Q+HISDTSVV+ +DN+R+L++D IIAE+KAQY++I
Sbjct: 226 EANVEALIQEIDFLRRLYEEEILILQSHISDTSVVVKLDNSRDLNMDCIIAEIKAQYDDI 285

Query: 345 AQRSRAEAESWYQTKYEELQVTAGRHGDDLRNTKQEIAEINRMIQRLRSEIDHVKKQCAN 404
             RSRAEAESWY++K EE++ T  RHG+ LR TK+EI E+NRMIQRL +E+++ K Q + 
Sbjct: 286 VTRSRAEAESWYRSKCEEMKATVIRHGETLRRTKEEINELNRMIQRLTAEVENAKCQNSK 345

Query: 405 LQAAIADAEQRGEMALKDAKNKLEGLEDALQKAKQDLARLLKEYQELMNVKLALDVEIAT 464
           L+AA+A +EQ+GE AL DA+ KL  LE ALQKAKQD+A L++EYQE+MN KL LD+EIAT
Sbjct: 346 LEAAVAQSEQQGEAALSDARCKLAELEGALQKAKQDMACLIREYQEVMNSKLGLDIEIAT 405

Query: 465 YRKLLEGEECRLNGEGVGQVNISVVQSTVSSGYGGASGVGSGLGLGGGSSYSYGSGLGVG 524
           YR+LLEGEE RL  EG+G VN+ V  S      G     GS    G   S      + V 
Sbjct: 406 YRRLLEGEEQRL-CEGIGAVNVCVSSSRGGVVCGDLCVSGSRPVTGSVCSAPCNGNVAVS 464

Query: 525 GGFSSSSGR---AIGGGLSSVGG-GSSTIKYTTTSSSSRK 560
            G  +  G+     GGG   VG  G S++   +  SS RK
Sbjct: 465 TGLCAPCGQLNTTCGGGSCGVGSCGISSLGVGSCGSSCRK 504


>gi|239755818 PREDICTED: hypothetical protein isoform 2 [Homo
           sapiens]
          Length = 486

 Score =  427 bits (1097), Expect = e-119
 Identities = 237/451 (52%), Positives = 312/451 (69%), Gaps = 30/451 (6%)

Query: 48  GGACGGAGFGSRSLYGLGGSK----RISIGGGSC--AISGGYGSRAG-GSYGFGGAGSGF 100
           G  CGG  F   S  G    +         G SC   ++GG+GS +  G +  G  G  F
Sbjct: 4   GSYCGGRAFSCISACGPRPGRCCITAAPYRGISCYRGLTGGFGSHSVCGGFRAGSCGRSF 63

Query: 101 GFGGGAGIGFGLGGGAGLAGGFGGPGFPVCPPGGIQEVTVNQSLLTPLNLQIDPTIQRVR 160
           G+                +GG  GP  P C    I  V+VN+SLLTPLNL+IDP  Q V+
Sbjct: 64  GYR---------------SGGVCGPS-PPC----ITTVSVNESLLTPLNLEIDPNAQCVK 103

Query: 161 AEEREQIKTLNNKFASFIDKVRFLEQQNKVLETKWTLLQEQGTKTVRQNLEPLFEQYINN 220
            EE+EQIK+LN++FA+FIDKVRFLEQQNK+LETK    Q +  +  + NLEPLFE YI  
Sbjct: 104 QEEKEQIKSLNSRFAAFIDKVRFLEQQNKLLETKLQFYQNR--ECCQSNLEPLFEGYIET 161

Query: 221 LRRQLDSIVGERGRLDSELRGMQDLVEDFKNKYEDEINKRTAAENEFVTLKKDVDAAYMN 280
           LRR+ + +  + GRL SEL  +Q+++E +K KYE+E++ R  AENEFV LKKDVD AY+ 
Sbjct: 162 LRREAECVEADSGRLASELNHVQEVLEGYKKKYEEEVSLRATAENEFVALKKDVDCAYLR 221

Query: 281 KVELQAKADTLTDEINFLRALYDAELSQMQTHISDTSVVLSMDNNRNLDLDSIIAEVKAQ 340
           K +L+A  + L  EI+FLR LY+ E+  +Q+HISDTSVV+ +DN+R+L++D IIAE+KAQ
Sbjct: 222 KSDLEANVEALIQEIDFLRRLYEEEIRVLQSHISDTSVVVKLDNSRDLNMDCIIAEIKAQ 281

Query: 341 YEEIAQRSRAEAESWYQTKYEELQVTAGRHGDDLRNTKQEIAEINRMIQRLRSEIDHVKK 400
           Y++I  RSRAEAESWY++K EE++ T  RHG+ LR TK+EI E+NRMIQRL +E+++ K 
Sbjct: 282 YDDIVTRSRAEAESWYRSKCEEMKATVIRHGETLRRTKEEINELNRMIQRLTAEVENAKC 341

Query: 401 QCANLQAAIADAEQRGEMALKDAKNKLEGLEDALQKAKQDLARLLKEYQELMNVKLALDV 460
           Q + L+AA+A +EQ+GE AL DA+ KL  LE ALQKAKQD+A L++EYQE+MN KL LD+
Sbjct: 342 QNSKLEAAVAQSEQQGEAALSDARCKLAELEGALQKAKQDMACLIREYQEVMNSKLGLDI 401

Query: 461 EIATYRKLLEGEECRLNGEGVGQVNISVVQS 491
           EIATYR+LLEGEE RL  EGVG VN+ V  S
Sbjct: 402 EIATYRRLLEGEEQRL-CEGVGSVNVCVSSS 431


>gi|239755816 PREDICTED: hypothetical protein isoform 1 [Homo
           sapiens]
          Length = 486

 Score =  427 bits (1097), Expect = e-119
 Identities = 237/451 (52%), Positives = 312/451 (69%), Gaps = 30/451 (6%)

Query: 48  GGACGGAGFGSRSLYGLGGSK----RISIGGGSC--AISGGYGSRAG-GSYGFGGAGSGF 100
           G  CGG  F   S  G    +         G SC   ++GG+GS +  G +  G  G  F
Sbjct: 4   GSYCGGRAFSCISACGPRPGRCCITAAPYRGISCYRGLTGGFGSHSVCGGFRAGSCGRSF 63

Query: 101 GFGGGAGIGFGLGGGAGLAGGFGGPGFPVCPPGGIQEVTVNQSLLTPLNLQIDPTIQRVR 160
           G+                +GG  GP  P C    I  V+VN+SLLTPLNL+IDP  Q V+
Sbjct: 64  GYR---------------SGGVCGPS-PPC----ITTVSVNESLLTPLNLEIDPNAQCVK 103

Query: 161 AEEREQIKTLNNKFASFIDKVRFLEQQNKVLETKWTLLQEQGTKTVRQNLEPLFEQYINN 220
            EE+EQIK+LN++FA+FIDKVRFLEQQNK+LETK    Q +  +  + NLEPLFE YI  
Sbjct: 104 QEEKEQIKSLNSRFAAFIDKVRFLEQQNKLLETKLQFYQNR--ECCQSNLEPLFEGYIET 161

Query: 221 LRRQLDSIVGERGRLDSELRGMQDLVEDFKNKYEDEINKRTAAENEFVTLKKDVDAAYMN 280
           LRR+ + +  + GRL SEL  +Q+++E +K KYE+E++ R  AENEFV LKKDVD AY+ 
Sbjct: 162 LRREAECVEADSGRLASELNHVQEVLEGYKKKYEEEVSLRATAENEFVALKKDVDCAYLR 221

Query: 281 KVELQAKADTLTDEINFLRALYDAELSQMQTHISDTSVVLSMDNNRNLDLDSIIAEVKAQ 340
           K +L+A  + L  EI+FLR LY+ E+  +Q+HISDTSVV+ +DN+R+L++D IIAE+KAQ
Sbjct: 222 KSDLEANVEALIQEIDFLRRLYEEEIRVLQSHISDTSVVVKLDNSRDLNMDCIIAEIKAQ 281

Query: 341 YEEIAQRSRAEAESWYQTKYEELQVTAGRHGDDLRNTKQEIAEINRMIQRLRSEIDHVKK 400
           Y++I  RSRAEAESWY++K EE++ T  RHG+ LR TK+EI E+NRMIQRL +E+++ K 
Sbjct: 282 YDDIVTRSRAEAESWYRSKCEEMKATVIRHGETLRRTKEEINELNRMIQRLTAEVENAKC 341

Query: 401 QCANLQAAIADAEQRGEMALKDAKNKLEGLEDALQKAKQDLARLLKEYQELMNVKLALDV 460
           Q + L+AA+A +EQ+GE AL DA+ KL  LE ALQKAKQD+A L++EYQE+MN KL LD+
Sbjct: 342 QNSKLEAAVAQSEQQGEAALSDARCKLAELEGALQKAKQDMACLIREYQEVMNSKLGLDI 401

Query: 461 EIATYRKLLEGEECRLNGEGVGQVNISVVQS 491
           EIATYR+LLEGEE RL  EGVG VN+ V  S
Sbjct: 402 EIATYRRLLEGEEQRL-CEGVGSVNVCVSSS 431


>gi|239755814 PREDICTED: hypothetical protein isoform 3 [Homo
           sapiens]
          Length = 486

 Score =  427 bits (1097), Expect = e-119
 Identities = 237/451 (52%), Positives = 312/451 (69%), Gaps = 30/451 (6%)

Query: 48  GGACGGAGFGSRSLYGLGGSK----RISIGGGSC--AISGGYGSRAG-GSYGFGGAGSGF 100
           G  CGG  F   S  G    +         G SC   ++GG+GS +  G +  G  G  F
Sbjct: 4   GSYCGGRAFSCISACGPRPGRCCITAAPYRGISCYRGLTGGFGSHSVCGGFRAGSCGRSF 63

Query: 101 GFGGGAGIGFGLGGGAGLAGGFGGPGFPVCPPGGIQEVTVNQSLLTPLNLQIDPTIQRVR 160
           G+                +GG  GP  P C    I  V+VN+SLLTPLNL+IDP  Q V+
Sbjct: 64  GYR---------------SGGVCGPS-PPC----ITTVSVNESLLTPLNLEIDPNAQCVK 103

Query: 161 AEEREQIKTLNNKFASFIDKVRFLEQQNKVLETKWTLLQEQGTKTVRQNLEPLFEQYINN 220
            EE+EQIK+LN++FA+FIDKVRFLEQQNK+LETK    Q +  +  + NLEPLFE YI  
Sbjct: 104 QEEKEQIKSLNSRFAAFIDKVRFLEQQNKLLETKLQFYQNR--ECCQSNLEPLFEGYIET 161

Query: 221 LRRQLDSIVGERGRLDSELRGMQDLVEDFKNKYEDEINKRTAAENEFVTLKKDVDAAYMN 280
           LRR+ + +  + GRL SEL  +Q+++E +K KYE+E++ R  AENEFV LKKDVD AY+ 
Sbjct: 162 LRREAECVEADSGRLASELNHVQEVLEGYKKKYEEEVSLRATAENEFVALKKDVDCAYLR 221

Query: 281 KVELQAKADTLTDEINFLRALYDAELSQMQTHISDTSVVLSMDNNRNLDLDSIIAEVKAQ 340
           K +L+A  + L  EI+FLR LY+ E+  +Q+HISDTSVV+ +DN+R+L++D IIAE+KAQ
Sbjct: 222 KSDLEANVEALIQEIDFLRRLYEEEIRVLQSHISDTSVVVKLDNSRDLNMDCIIAEIKAQ 281

Query: 341 YEEIAQRSRAEAESWYQTKYEELQVTAGRHGDDLRNTKQEIAEINRMIQRLRSEIDHVKK 400
           Y++I  RSRAEAESWY++K EE++ T  RHG+ LR TK+EI E+NRMIQRL +E+++ K 
Sbjct: 282 YDDIVTRSRAEAESWYRSKCEEMKATVIRHGETLRRTKEEINELNRMIQRLTAEVENAKC 341

Query: 401 QCANLQAAIADAEQRGEMALKDAKNKLEGLEDALQKAKQDLARLLKEYQELMNVKLALDV 460
           Q + L+AA+A +EQ+GE AL DA+ KL  LE ALQKAKQD+A L++EYQE+MN KL LD+
Sbjct: 342 QNSKLEAAVAQSEQQGEAALSDARCKLAELEGALQKAKQDMACLIREYQEVMNSKLGLDI 401

Query: 461 EIATYRKLLEGEECRLNGEGVGQVNISVVQS 491
           EIATYR+LLEGEE RL  EGVG VN+ V  S
Sbjct: 402 EIATYRRLLEGEEQRL-CEGVGSVNVCVSSS 431


>gi|14318422 keratin 86 [Homo sapiens]
          Length = 486

 Score =  427 bits (1097), Expect = e-119
 Identities = 237/451 (52%), Positives = 312/451 (69%), Gaps = 30/451 (6%)

Query: 48  GGACGGAGFGSRSLYGLGGSK----RISIGGGSC--AISGGYGSRAG-GSYGFGGAGSGF 100
           G  CGG  F   S  G    +         G SC   ++GG+GS +  G +  G  G  F
Sbjct: 4   GSYCGGRAFSCISACGPRPGRCCITAAPYRGISCYRGLTGGFGSHSVCGGFRAGSCGRSF 63

Query: 101 GFGGGAGIGFGLGGGAGLAGGFGGPGFPVCPPGGIQEVTVNQSLLTPLNLQIDPTIQRVR 160
           G+                +GG  GP  P C    I  V+VN+SLLTPLNL+IDP  Q V+
Sbjct: 64  GYR---------------SGGVCGPS-PPC----ITTVSVNESLLTPLNLEIDPNAQCVK 103

Query: 161 AEEREQIKTLNNKFASFIDKVRFLEQQNKVLETKWTLLQEQGTKTVRQNLEPLFEQYINN 220
            EE+EQIK+LN++FA+FIDKVRFLEQQNK+LETK    Q +  +  + NLEPLFE YI  
Sbjct: 104 QEEKEQIKSLNSRFAAFIDKVRFLEQQNKLLETKLQFYQNR--ECCQSNLEPLFEGYIET 161

Query: 221 LRRQLDSIVGERGRLDSELRGMQDLVEDFKNKYEDEINKRTAAENEFVTLKKDVDAAYMN 280
           LRR+ + +  + GRL SEL  +Q+++E +K KYE+E++ R  AENEFV LKKDVD AY+ 
Sbjct: 162 LRREAECVEADSGRLASELNHVQEVLEGYKKKYEEEVSLRATAENEFVALKKDVDCAYLR 221

Query: 281 KVELQAKADTLTDEINFLRALYDAELSQMQTHISDTSVVLSMDNNRNLDLDSIIAEVKAQ 340
           K +L+A  + L  EI+FLR LY+ E+  +Q+HISDTSVV+ +DN+R+L++D IIAE+KAQ
Sbjct: 222 KSDLEANVEALIQEIDFLRRLYEEEIRVLQSHISDTSVVVKLDNSRDLNMDCIIAEIKAQ 281

Query: 341 YEEIAQRSRAEAESWYQTKYEELQVTAGRHGDDLRNTKQEIAEINRMIQRLRSEIDHVKK 400
           Y++I  RSRAEAESWY++K EE++ T  RHG+ LR TK+EI E+NRMIQRL +E+++ K 
Sbjct: 282 YDDIVTRSRAEAESWYRSKCEEMKATVIRHGETLRRTKEEINELNRMIQRLTAEVENAKC 341

Query: 401 QCANLQAAIADAEQRGEMALKDAKNKLEGLEDALQKAKQDLARLLKEYQELMNVKLALDV 460
           Q + L+AA+A +EQ+GE AL DA+ KL  LE ALQKAKQD+A L++EYQE+MN KL LD+
Sbjct: 342 QNSKLEAAVAQSEQQGEAALSDARCKLAELEGALQKAKQDMACLIREYQEVMNSKLGLDI 401

Query: 461 EIATYRKLLEGEECRLNGEGVGQVNISVVQS 491
           EIATYR+LLEGEE RL  EGVG VN+ V  S
Sbjct: 402 EIATYRRLLEGEEQRL-CEGVGSVNVCVSSS 431


>gi|169790841 keratin 83 [Homo sapiens]
          Length = 493

 Score =  422 bits (1085), Expect = e-118
 Identities = 250/516 (48%), Positives = 329/516 (63%), Gaps = 32/516 (6%)

Query: 32  GFSSVSVSRSRGSGGLGGACGGAGFGSRSLYGLGGSKRISIGGGSCAISGGYGSRAG-GS 90
           GF+S+      G+     ACG     SR        + IS   G   ++GG+GS +  G 
Sbjct: 4   GFNSIGCGFRPGNFSCVSACGPRP--SRCCITAAPYRGISCYRG---LTGGFGSHSVCGG 58

Query: 91  YGFGGAGSGFGFGGGAGIGFGLGGGAGLAGGFGGPGFPVCPPGGIQEVTVNQSLLTPLNL 150
           +  G  G  FG+                +GG  GP  P C    I  V+VN+SLLTPLNL
Sbjct: 59  FRAGSCGRSFGYR---------------SGGVCGPS-PPC----ITTVSVNESLLTPLNL 98

Query: 151 QIDPTIQRVRAEEREQIKTLNNKFASFIDKVRFLEQQNKVLETKWTLLQEQGTKTVRQNL 210
           +IDP  Q V+ EE+EQIK+LN++FA+FIDKVRFLEQQNK+LETK    Q +  +  + NL
Sbjct: 99  EIDPNAQCVKQEEKEQIKSLNSRFAAFIDKVRFLEQQNKLLETKLQFYQNR--ECCQSNL 156

Query: 211 EPLFEQYINNLRRQLDSIVGERGRLDSELRGMQDLVEDFKNKYEDEINKRTAAENEFVTL 270
           EPLF  YI  LRR+ + +  + GRL SEL  +Q+++E +K KYE+E+  R  AENEFV L
Sbjct: 157 EPLFAGYIETLRREAECVEADSGRLASELNHVQEVLEGYKKKYEEEVALRATAENEFVAL 216

Query: 271 KKDVDAAYMNKVELQAKADTLTDEINFLRALYDAELSQMQTHISDTSVVLSMDNNRNLDL 330
           KKDVD AY+ K +L+A  + L  EI+FLR LY+ E+  +Q+HISDTSVV+ +DN+R+L++
Sbjct: 217 KKDVDCAYLRKSDLEANVEALIQEIDFLRRLYEEEIRILQSHISDTSVVVKLDNSRDLNM 276

Query: 331 DSIIAEVKAQYEEIAQRSRAEAESWYQTKYEELQVTAGRHGDDLRNTKQEIAEINRMIQR 390
           D I+AE+KAQY++IA RSRAEAESWY++K EE++ T  RHG+ LR TK+EI E+NRMIQR
Sbjct: 277 DCIVAEIKAQYDDIATRSRAEAESWYRSKCEEMKATVIRHGETLRRTKEEINELNRMIQR 336

Query: 391 LRSEIDHVKKQCANLQAAIADAEQRGEMALKDAKNKLEGLEDALQKAKQDLARLLKEYQE 450
           L +E+++ K Q + L+AA+A +EQ+GE AL DA+ KL  LE ALQKAKQD+A L++EYQE
Sbjct: 337 LTAEVENAKCQNSKLEAAVAQSEQQGEAALSDARCKLAELEGALQKAKQDMACLIREYQE 396

Query: 451 LMNVKLALDVEIATYRKLLEGEECRLNGEGVGQVNISVVQSTVSSGYGGASGVGSGLGLG 510
           +MN KL LD+EIATYR+LLEGEE RL  EGV  VN+ V  S      G     GS    G
Sbjct: 397 VMNSKLGLDIEIATYRRLLEGEEQRL-CEGVEAVNVCVSSSRGGVVCGDLCVSGSRPVTG 455

Query: 511 GGSSYSYGSGLGVGGGFSSSSGR---AIGGGLSSVG 543
              S      L V  G     G+     GGG    G
Sbjct: 456 SVCSAPCNGNLVVSTGLCKPCGQLNTTCGGGSCGQG 491


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.312    0.132    0.366 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 20,012,800
Number of Sequences: 37866
Number of extensions: 1091912
Number of successful extensions: 26365
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 426
Number of HSP's successfully gapped in prelim test: 753
Number of HSP's that attempted gapping in prelim test: 7849
Number of HSP's gapped (non-prelim): 8351
length of query: 564
length of database: 18,247,518
effective HSP length: 108
effective length of query: 456
effective length of database: 14,157,990
effective search space: 6456043440
effective search space used: 6456043440
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.