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Search of human proteins with 50083287
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|50083287 LIM homeobox 8 [Homo sapiens]
(356 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|50083287 LIM homeobox 8 [Homo sapiens] 742 0.0
gi|134284361 LIM homeobox protein 6 isoform 2 [Homo sapiens] 414 e-116
gi|134284359 LIM homeobox protein 6 isoform 1 [Homo sapiens] 402 e-112
gi|33569216 LIM homeobox 9 isoform 1 [Homo sapiens] 174 8e-44
gi|62241033 LIM homeobox 9 isoform 2 [Homo sapiens] 174 8e-44
gi|4505007 LIM homeobox transcription factor 1, beta [Homo sapiens] 165 5e-41
gi|115387114 islet-1 [Homo sapiens] 160 1e-39
gi|30795196 LIM homeobox protein 2 [Homo sapiens] 159 4e-39
gi|28893581 LIM homeobox transcription factor 1, alpha isoform a... 159 5e-39
gi|21956641 ISL LIM homeobox 2 [Homo sapiens] 159 5e-39
gi|30023847 LIM homeobox protein 3 isoform a [Homo sapiens] 157 1e-38
gi|7657303 LIM homeobox protein 3 isoform b [Homo sapiens] 157 1e-38
gi|11641283 LIM homeobox protein 5 [Homo sapiens] 157 2e-38
gi|15375314 LIM homeobox protein 4 [Homo sapiens] 152 4e-37
gi|30410785 LIM homeobox protein 1 [Homo sapiens] 149 3e-36
gi|5803072 LIM domain only 4 [Homo sapiens] 110 3e-24
gi|4505005 LIM domain only 1 [Homo sapiens] 100 2e-21
gi|21361802 LIM domain only 3 [Homo sapiens] 100 3e-21
gi|47778935 LIM domain only 3 [Homo sapiens] 100 3e-21
gi|214832074 LIM domain only 2 isoform 1 [Homo sapiens] 95 1e-19
gi|214832219 LIM domain only 2 isoform 2 [Homo sapiens] 90 3e-18
gi|214832121 LIM domain only 2 isoform 2 [Homo sapiens] 90 3e-18
gi|51173715 actin-binding LIM protein 1 isoform c [Homo sapiens] 78 1e-14
gi|51173713 actin-binding LIM protein 1 isoform b [Homo sapiens] 78 1e-14
gi|51173711 actin-binding LIM protein 1 isoform a [Homo sapiens] 78 1e-14
gi|4505001 LIM domain kinase 1 [Homo sapiens] 77 2e-14
gi|194272207 actin binding LIM protein family, member 2 isoform ... 74 3e-13
gi|153792514 actin binding LIM protein family, member 2 isoform ... 74 3e-13
gi|194272204 actin binding LIM protein family, member 2 isoform ... 74 3e-13
gi|194272202 actin binding LIM protein family, member 2 isoform ... 74 3e-13
>gi|50083287 LIM homeobox 8 [Homo sapiens]
Length = 356
Score = 742 bits (1916), Expect = 0.0
Identities = 356/356 (100%), Positives = 356/356 (100%)
Query: 1 MQILSRCQGLMSEECGRTTALAAGRTRKGAGEEGLVSPEGAGDEDSCSSSAPLSPSSSPR 60
MQILSRCQGLMSEECGRTTALAAGRTRKGAGEEGLVSPEGAGDEDSCSSSAPLSPSSSPR
Sbjct: 1 MQILSRCQGLMSEECGRTTALAAGRTRKGAGEEGLVSPEGAGDEDSCSSSAPLSPSSSPR 60
Query: 61 SMASGSGCPPGKCVCNSCGLEIVDKYLLKVNDLCWHVRCLSCSVCRTSLGRHTSCYIKDK 120
SMASGSGCPPGKCVCNSCGLEIVDKYLLKVNDLCWHVRCLSCSVCRTSLGRHTSCYIKDK
Sbjct: 61 SMASGSGCPPGKCVCNSCGLEIVDKYLLKVNDLCWHVRCLSCSVCRTSLGRHTSCYIKDK 120
Query: 121 DIFCKLDYFRRYGTRCSRCGRHIHSTDWVRRAKGNVYHLACFACFSCKRQLSTGEEFALV 180
DIFCKLDYFRRYGTRCSRCGRHIHSTDWVRRAKGNVYHLACFACFSCKRQLSTGEEFALV
Sbjct: 121 DIFCKLDYFRRYGTRCSRCGRHIHSTDWVRRAKGNVYHLACFACFSCKRQLSTGEEFALV 180
Query: 181 EEKVLCRVHYDCMLDNLKREVENGNGISVEGALLTEQDVNHPKPAKRARTSFTADQLQVM 240
EEKVLCRVHYDCMLDNLKREVENGNGISVEGALLTEQDVNHPKPAKRARTSFTADQLQVM
Sbjct: 181 EEKVLCRVHYDCMLDNLKREVENGNGISVEGALLTEQDVNHPKPAKRARTSFTADQLQVM 240
Query: 241 QAQFAQDNNPDAQTLQKLAERTGLSRRVIQVWFQNCRARHKKHVSPNHSSSTPVTAVPPS 300
QAQFAQDNNPDAQTLQKLAERTGLSRRVIQVWFQNCRARHKKHVSPNHSSSTPVTAVPPS
Sbjct: 241 QAQFAQDNNPDAQTLQKLAERTGLSRRVIQVWFQNCRARHKKHVSPNHSSSTPVTAVPPS 300
Query: 301 RLSPPMLEEMAYSAYVPQDGTMLTALHSYMDAHSPTTLGLQPLLPHSMTQLPISHT 356
RLSPPMLEEMAYSAYVPQDGTMLTALHSYMDAHSPTTLGLQPLLPHSMTQLPISHT
Sbjct: 301 RLSPPMLEEMAYSAYVPQDGTMLTALHSYMDAHSPTTLGLQPLLPHSMTQLPISHT 356
>gi|134284361 LIM homeobox protein 6 isoform 2 [Homo sapiens]
Length = 377
Score = 414 bits (1064), Expect = e-116
Identities = 206/344 (59%), Positives = 253/344 (73%), Gaps = 8/344 (2%)
Query: 15 CGRTTALAAGRTRKGAGEEGLVSPEGAGDEDSCSSS--APLSPSSSPRSMASGSGCPPGK 72
C TT G + + GA D+D +S P +PS A+ S GK
Sbjct: 37 CKATTRCLEGTAPPAMAQSDAEALAGALDKDEGQASPCTPSTPSVCSPPSAASSVPSAGK 96
Query: 73 CVCNSCGLEIVDKYLLKVNDLCWHVRCLSCSVCRTSLGRHTSCYIKDKDIFCKLDYFRRY 132
+C+SCGLEI+D+YLLKVN+L WHVRCL CSVCRTSL + SCYIK+K+IFCK+DYF R+
Sbjct: 97 NICSSCGLEILDRYLLKVNNLIWHVRCLECSVCRTSLRQQNSCYIKNKEIFCKMDYFSRF 156
Query: 133 GTRCSRCGRHIHSTDWVRRAKGNVYHLACFACFSCKRQLSTGEEFALVEEKVLCRVHYDC 192
GT+C+RCGR I+++DWVRRA+GN YHLACFACFSCKRQLSTGEEF LVEEKVLCR+HYD
Sbjct: 157 GTKCARCGRQIYASDWVRRARGNAYHLACFACFSCKRQLSTGEEFGLVEEKVLCRIHYDT 216
Query: 193 MLDNLKREVENGNGISVEGALLTEQDVNHPKPAKRARTSFTADQLQVMQAQFAQDNNPDA 252
M++NLKR ENGNG+++EGA+ +EQD + PKPAKRARTSFTA+QLQVMQAQFAQDNNPDA
Sbjct: 217 MIENLKRAAENGNGLTLEGAVPSEQD-SQPKPAKRARTSFTAEQLQVMQAQFAQDNNPDA 275
Query: 253 QTLQKLAERTGLSRRVIQVWFQNCRARHKKHVSPNHSSSTPVTAVPPSRLSPPMLEEMAY 312
QTLQKLA+ TGLSRRVIQVWFQNCRARHKKH +P H P + PPSRL + +++ Y
Sbjct: 276 QTLQKLADMTGLSRRVIQVWFQNCRARHKKH-TPQH--PVPPSGAPPSRLPSALSDDIHY 332
Query: 313 SAYVPQDGTMLTALHSYMDAH--SPTTLGLQPLLPHSMTQLPIS 354
+ + + + LH Y+++H S TL P LP QLP+S
Sbjct: 333 TPFSSPERARMVTLHGYIESHPFSVLTLPALPHLPVGAPQLPLS 376
>gi|134284359 LIM homeobox protein 6 isoform 1 [Homo sapiens]
Length = 392
Score = 402 bits (1032), Expect = e-112
Identities = 195/320 (60%), Positives = 241/320 (75%), Gaps = 6/320 (1%)
Query: 15 CGRTTALAAGRTRKGAGEEGLVSPEGAGDEDSCSSS--APLSPSSSPRSMASGSGCPPGK 72
C TT G + + GA D+D +S P +PS A+ S GK
Sbjct: 37 CKATTRCLEGTAPPAMAQSDAEALAGALDKDEGQASPCTPSTPSVCSPPSAASSVPSAGK 96
Query: 73 CVCNSCGLEIVDKYLLKVNDLCWHVRCLSCSVCRTSLGRHTSCYIKDKDIFCKLDYFRRY 132
+C+SCGLEI+D+YLLKVN+L WHVRCL CSVCRTSL + SCYIK+K+IFCK+DYF R+
Sbjct: 97 NICSSCGLEILDRYLLKVNNLIWHVRCLECSVCRTSLRQQNSCYIKNKEIFCKMDYFSRF 156
Query: 133 GTRCSRCGRHIHSTDWVRRAKGNVYHLACFACFSCKRQLSTGEEFALVEEKVLCRVHYDC 192
GT+C+RCGR I+++DWVRRA+GN YHLACFACFSCKRQLSTGEEF LVEEKVLCR+HYD
Sbjct: 157 GTKCARCGRQIYASDWVRRARGNAYHLACFACFSCKRQLSTGEEFGLVEEKVLCRIHYDT 216
Query: 193 MLDNLKREVENGNGISVEGALLTEQDVNHPKPAKRARTSFTADQLQVMQAQFAQDNNPDA 252
M++NLKR ENGNG+++EGA+ +EQD + PKPAKRARTSFTA+QLQVMQAQFAQDNNPDA
Sbjct: 217 MIENLKRAAENGNGLTLEGAVPSEQD-SQPKPAKRARTSFTAEQLQVMQAQFAQDNNPDA 275
Query: 253 QTLQKLAERTGLSRRVIQVWFQNCRARHKKHVSPNHSSSTPVTAVPPSRLSPPMLEEMAY 312
QTLQKLA+ TGLSRRVIQVWFQNCRARHKKH +P H P + PPSRL + +++ Y
Sbjct: 276 QTLQKLADMTGLSRRVIQVWFQNCRARHKKH-TPQH--PVPPSGAPPSRLPSALSDDIHY 332
Query: 313 SAYVPQDGTMLTALHSYMDA 332
+ + + + LH Y+++
Sbjct: 333 TPFSSPERARMVTLHGYIES 352
>gi|33569216 LIM homeobox 9 isoform 1 [Homo sapiens]
Length = 397
Score = 174 bits (442), Expect = 8e-44
Identities = 111/331 (33%), Positives = 169/331 (51%), Gaps = 63/331 (19%)
Query: 69 PPGKCVCNSCGLEIVDKYLLKVNDLCWHVRCLSCSVCRTSLGRHTSCYIKDKDIFCKLDY 128
P +C CG +I D+Y L D WH+RCL C C+ +L +C+ KD I+CK DY
Sbjct: 65 PEKPALCAGCGGKISDRYYLLAVDKQWHLRCLKCCECKLALESELTCFAKDGSIYCKEDY 124
Query: 129 FRRYGT-RCSRCGRHIHSTDWVRRAKGNVYHLACFACFSCKRQLSTGEEFALVEEKVLCR 187
+RR+ RC+RC I +++ V RA+ +VYHL+CF C +C + L+TG+ F + + V CR
Sbjct: 125 YRRFSVQRCARCHLGISASEMVMRARDSVYHLSCFTCSTCNKTLTTGDHFGMKDSLVYCR 184
Query: 188 VHYDCMLD-----------------NLKREVENGNGISVEG------------------A 212
H++ +L L NG G +G +
Sbjct: 185 AHFETLLQGEYPPQLSYTELAAKSGGLALPYFNGTGTVQKGRPRKRKSPALGVDIVNYNS 244
Query: 213 LLTEQDVNH------PKP----AKRARTSFTADQLQVMQAQFAQDNNPDAQTLQKLAERT 262
E + +H P P KR RTSF QL+ M++ FA ++NPDA+ L++LA++T
Sbjct: 245 GCNENEADHLDRDQQPYPPSQKTKRMRTSFKHHQLRTMKSYFAINHNPDAKDLKQLAQKT 304
Query: 263 GLSRRVIQVWFQNCRARHKKHV------SPNHSSSTPVTAVPPS----RLSPPMLEEMAY 312
GL++RV+QVWFQN RA+ ++++ + + T + A PPS L+PP
Sbjct: 305 GLTKRVLQVWFQNARAKFRRNLLRQENGGVDKADGTSLPA-PPSADSGALTPPGTATTLT 363
Query: 313 SAYVPQDGTMLTALHSYMDAH-----SPTTL 338
P T++T++ S MD+H S TTL
Sbjct: 364 DLTNPTI-TVVTSVTSNMDSHESGSPSQTTL 393
>gi|62241033 LIM homeobox 9 isoform 2 [Homo sapiens]
Length = 388
Score = 174 bits (442), Expect = 8e-44
Identities = 111/331 (33%), Positives = 169/331 (51%), Gaps = 63/331 (19%)
Query: 69 PPGKCVCNSCGLEIVDKYLLKVNDLCWHVRCLSCSVCRTSLGRHTSCYIKDKDIFCKLDY 128
P +C CG +I D+Y L D WH+RCL C C+ +L +C+ KD I+CK DY
Sbjct: 56 PEKPALCAGCGGKISDRYYLLAVDKQWHLRCLKCCECKLALESELTCFAKDGSIYCKEDY 115
Query: 129 FRRYGT-RCSRCGRHIHSTDWVRRAKGNVYHLACFACFSCKRQLSTGEEFALVEEKVLCR 187
+RR+ RC+RC I +++ V RA+ +VYHL+CF C +C + L+TG+ F + + V CR
Sbjct: 116 YRRFSVQRCARCHLGISASEMVMRARDSVYHLSCFTCSTCNKTLTTGDHFGMKDSLVYCR 175
Query: 188 VHYDCMLD-----------------NLKREVENGNGISVEG------------------A 212
H++ +L L NG G +G +
Sbjct: 176 AHFETLLQGEYPPQLSYTELAAKSGGLALPYFNGTGTVQKGRPRKRKSPALGVDIVNYNS 235
Query: 213 LLTEQDVNH------PKP----AKRARTSFTADQLQVMQAQFAQDNNPDAQTLQKLAERT 262
E + +H P P KR RTSF QL+ M++ FA ++NPDA+ L++LA++T
Sbjct: 236 GCNENEADHLDRDQQPYPPSQKTKRMRTSFKHHQLRTMKSYFAINHNPDAKDLKQLAQKT 295
Query: 263 GLSRRVIQVWFQNCRARHKKHV------SPNHSSSTPVTAVPPS----RLSPPMLEEMAY 312
GL++RV+QVWFQN RA+ ++++ + + T + A PPS L+PP
Sbjct: 296 GLTKRVLQVWFQNARAKFRRNLLRQENGGVDKADGTSLPA-PPSADSGALTPPGTATTLT 354
Query: 313 SAYVPQDGTMLTALHSYMDAH-----SPTTL 338
P T++T++ S MD+H S TTL
Sbjct: 355 DLTNPTI-TVVTSVTSNMDSHESGSPSQTTL 384
>gi|4505007 LIM homeobox transcription factor 1, beta [Homo sapiens]
Length = 372
Score = 165 bits (418), Expect = 5e-41
Identities = 92/245 (37%), Positives = 132/245 (53%), Gaps = 18/245 (7%)
Query: 53 LSPSSSPRSMASGSGCPPGKCVCNSCGLEIVDKYLLKVNDLCWHVRCLSCSVCRTSLGRH 112
L P + + GS CP VC C I D++L++VN+ WH CL C+ C+ +L
Sbjct: 12 LRPGPATLGVLLGSDCPH-PAVCEGCQRPISDRFLMRVNESSWHEECLQCAACQQALT-- 68
Query: 113 TSCYIKDKDIFCKLDYFRRYGTRCSRCGRHIHSTDWVRRAKGNVYHLACFACFSCKRQLS 172
TSCY +D+ ++CK DY + + +CS C I T++V RA VYHL CF C C+RQL
Sbjct: 69 TSCYFRDRKLYCKQDYQQLFAAKCSGCMEKIAPTEFVMRALECVYHLGCFCCCVCERQLR 128
Query: 173 TGEEFALVEEKVLCRVHYD-----------CMLDNLKREVENGNGISVEG----ALLTEQ 217
G+EF L E ++LC+ Y+ D++K E E+G+ +G + +
Sbjct: 129 KGDEFVLKEGQLLCKGDYEKEKDLLSSVSPDESDSVKSEDEDGDMKPAKGQGSQSKGSGD 188
Query: 218 DVNHPKPAKRARTSFTADQLQVMQAQFAQDNNPDAQTLQKLAERTGLSRRVIQVWFQNCR 277
D P+ KR RT T Q + +A F + P + + LA TGLS RV+QVWFQN R
Sbjct: 189 DGKDPRRPKRPRTILTTQQRRAFKASFEVSSKPCRKVRETLAAETGLSVRVVQVWFQNQR 248
Query: 278 ARHKK 282
A+ KK
Sbjct: 249 AKMKK 253
>gi|115387114 islet-1 [Homo sapiens]
Length = 349
Score = 160 bits (406), Expect = 1e-39
Identities = 93/268 (34%), Positives = 130/268 (48%), Gaps = 33/268 (12%)
Query: 67 GCPPGK----CVCNSCGLEIVDKYLLKVN-DLCWHVRCLSCSVCRTSLGRHTSCYIKDKD 121
G PP K +C CG +I D+Y+L+V+ DL WH CL C+ C L +C+++D
Sbjct: 5 GDPPKKKRLISLCVGCGNQIHDQYILRVSPDLEWHAACLKCAECNQYLDESCTCFVRDGK 64
Query: 122 IFCKLDYFRRYGTRCSRCGRHIHSTDWVRRAKGNVYHLACFACFSCKRQLSTGEEFALVE 181
+CK DY R YG +C++C D+V RA+ VYH+ CF C +C RQL G+EFAL E
Sbjct: 65 TYCKRDYIRLYGIKCAKCSIGFSKNDFVMRARSKVYHIECFRCVACSRQLIPGDEFALRE 124
Query: 182 EKVLCRVHYDCM-------------LDNLKREVENGNGISVEGALLTEQDVNHPKPAKRA 228
+ + CR +D + L + IS L P+ R
Sbjct: 125 DGLFCRADHDVVERASLGAGDPLSPLHPARPLQMAAEPISARQPALRPHVHKQPEKTTRV 184
Query: 229 RTSFTADQLQVMQAQFAQDNNPDAQTLQKLAERTGLSRRVIQVWFQNCRARHKK------ 282
RT QL ++ +A + PDA ++L E TGLS RVI+VWFQN R + KK
Sbjct: 185 RTVLNEKQLHTLRTCYAANPRPDALMKEQLVEMTGLSPRVIRVWFQNKRCKDKKRSIMMK 244
Query: 283 ---HVSPNHSSS------TPVTAVPPSR 301
PN ++ TP+ A P R
Sbjct: 245 QLQQQQPNDKTNIQGMTGTPMVAASPER 272
>gi|30795196 LIM homeobox protein 2 [Homo sapiens]
Length = 406
Score = 159 bits (402), Expect = 4e-39
Identities = 104/344 (30%), Positives = 159/344 (46%), Gaps = 83/344 (24%)
Query: 74 VCNSCGLEIVDKYLLKVNDLCWHVRCLSCSVCRTSLGRHTSCYIKDKDIFCKLDYFRRYG 133
+C CG +I D+Y L D WH+RCL C C+ +L +C+ KD I+CK DY+RR+
Sbjct: 52 LCAGCGGKISDRYYLLAVDKQWHMRCLKCCECKLNLESELTCFSKDGSIYCKEDYYRRFS 111
Query: 134 T-RCSRCGRHIHSTDWVRRAKGNVYHLACFACFSCKRQLSTGEEFALVEEKVLCRV---- 188
RC+RC I +++ V RA+ VYHL CF C +C + L+TG+ F + + V CR+
Sbjct: 112 VQRCARCHLGISASEMVMRARDLVYHLNCFTCTTCNKMLTTGDHFGMKDSLVYCRLHFEA 171
Query: 189 -----------HYDCMLDNLKREVENGNGISVEGA------------------------- 212
H D G+ GA
Sbjct: 172 LLQGEYPAHFNHADVAAAAAAAAAAKSAGLGAAGANPLGLPYYNGVGTVQKGRPRKRKSP 231
Query: 213 -------------LLTEQDVNH-----PKPA----KRARTSFTADQLQVMQAQFAQDNNP 250
E D H P P+ KR RTSF QL+ M++ FA ++NP
Sbjct: 232 GPGADLAAYNAALSCNENDAEHLDRDQPYPSSQKTKRMRTSFKHHQLRTMKSYFAINHNP 291
Query: 251 DAQTLQKLAERTGLSRRVIQVWFQNCRARHKKHV----------SPNHSSSTPVTAVPPS 300
DA+ L++LA++TGL++RV+QVWFQN RA+ ++++ S + + T + P S
Sbjct: 292 DAKDLKQLAQKTGLTKRVLQVWFQNARAKFRRNLLRQENTGVDKSTDAALQTGTPSGPAS 351
Query: 301 RLS---------PPMLEEMAYSAYVPQDGTMLTALHSYMDAHSP 335
LS P L ++ S +P ++LT++ ++ H P
Sbjct: 352 ELSNASLSPSSTPTTLTDLT-SPTLPTVTSVLTSVPGNLEGHEP 394
>gi|28893581 LIM homeobox transcription factor 1, alpha isoform a
[Homo sapiens]
Length = 382
Score = 159 bits (401), Expect = 5e-39
Identities = 85/224 (37%), Positives = 125/224 (55%), Gaps = 16/224 (7%)
Query: 72 KCVCNSCGLEIVDKYLLKVNDLCWHVRCLSCSVCRTSLGRHTSCYIKDKDIFCKLDYFRR 131
K VC C I+D++LL++ND WH +C+ C+ C+ L T+C+ +DK ++CK DY +
Sbjct: 32 KSVCEGCQRVILDRFLLRLNDSFWHEQCVQCASCKEPL--ETTCFYRDKKLYCKYDYEKL 89
Query: 132 YGTRCSRCGRHIHSTDWVRRAKGNVYHLACFACFSCKRQLSTGEEFALVEEKVLCRVHYD 191
+ +C C I ++V RA+ +VYHL+CF C C+RQL G+EF L E ++LC+ Y+
Sbjct: 90 FAVKCGGCFEAIAPNEFVMRAQKSVYHLSCFCCCVCERQLQKGDEFVLKEGQLLCKGDYE 149
Query: 192 -----------CMLDNLKREVENGNGISVEGA--LLTEQDVNHPKPAKRARTSFTADQLQ 238
D+ K + E S GA E+ +H +P KR RT T Q +
Sbjct: 150 KERELLSLVSPAASDSGKSDDEESLCKSAHGAGKGTAEEGKDHKRP-KRPRTILTTQQRR 208
Query: 239 VMQAQFAQDNNPDAQTLQKLAERTGLSRRVIQVWFQNCRARHKK 282
+A F + P + + LA TGLS RV+QVWFQN RA+ KK
Sbjct: 209 AFKASFEVSSKPCRKVRETLAAETGLSVRVVQVWFQNQRAKMKK 252
>gi|21956641 ISL LIM homeobox 2 [Homo sapiens]
Length = 359
Score = 159 bits (401), Expect = 5e-39
Identities = 85/236 (36%), Positives = 125/236 (52%), Gaps = 14/236 (5%)
Query: 61 SMASGSGCPPGKCVCNSCGLEIVDKYLLKVN-DLCWHVRCLSCSVCRTSLGRHTSCYIKD 119
+M S PG +C CG +I D+++L+V+ DL WH CL C+ C L +C+++D
Sbjct: 13 AMGDHSKKKPGTAMCVGCGSQIHDQFILRVSPDLEWHAACLKCAECSQYLDETCTCFVRD 72
Query: 120 KDIFCKLDYFRRYGTRCSRCGRHIHSTDWVRRAKGNVYHLACFACFSCKRQLSTGEEFAL 179
+CK DY R +G +C++C S+D V RA+ +VYH+ CF C C RQL G+EF+L
Sbjct: 73 GKTYCKRDYVRLFGIKCAKCQVGFSSSDLVMRARDSVYHIECFRCSVCSRQLLPGDEFSL 132
Query: 180 VEEKVLCRVHYDCMLDNLKR-------EVENGNGISVEGALLTEQDVNHPKPAK------ 226
E ++LCR + +L+ + G+ + A Q P K
Sbjct: 133 REHELLCRADHGLLLERAAAGSPRSPGPLPGARGLHLPDAGSGRQPALRPHVHKQTEKTT 192
Query: 227 RARTSFTADQLQVMQAQFAQDNNPDAQTLQKLAERTGLSRRVIQVWFQNCRARHKK 282
R RT QL ++ +A + PDA ++L E TGLS RVI+VWFQN R + KK
Sbjct: 193 RVRTVLNEKQLHTLRTCYAANPRPDALMKEQLVEMTGLSPRVIRVWFQNKRCKDKK 248
>gi|30023847 LIM homeobox protein 3 isoform a [Homo sapiens]
Length = 397
Score = 157 bits (398), Expect = 1e-38
Identities = 81/210 (38%), Positives = 120/210 (57%), Gaps = 26/210 (12%)
Query: 74 VCNSCGLEIVDKYLLKVNDLCWHVRCLSCSVCRTSLGRHTSCYIKDKDIFCKLDYFRRYG 133
+C C I+D+++LK D WH +CL CS C T L C+ + + ++CK D+F+R+G
Sbjct: 30 LCAGCDQHILDRFILKALDRHWHSKCLKCSDCHTPLAER--CFSRGESVYCKDDFFKRFG 87
Query: 134 TRCSRCGRHIHSTDWVRRAKGNVYHLACFACFSCKRQLSTGEEFALVEE-KVLCRVHYDC 192
T+C+ C I T VRRA+ VYHL CFAC CKRQL+TG+EF L+E+ +++C+ Y+
Sbjct: 88 TKCAACQLGIPPTQVVRRAQDFVYHLHCFACVVCKRQLATGDEFYLMEDSRLVCKADYET 147
Query: 193 MLDNLKREVENGNGISVEGALLTEQDVNHPKPAKRARTSFTADQLQVMQAQFAQDNNPDA 252
+RE E AKR RT+ TA QL+ +++ + P
Sbjct: 148 A---KQREAE--------------------ATAKRPRTTITAKQLETLKSAYNTSPKPAR 184
Query: 253 QTLQKLAERTGLSRRVIQVWFQNCRARHKK 282
++L+ TGL RV+QVWFQN RA+ K+
Sbjct: 185 HVREQLSSETGLDMRVVQVWFQNRRAKEKR 214
>gi|7657303 LIM homeobox protein 3 isoform b [Homo sapiens]
Length = 402
Score = 157 bits (398), Expect = 1e-38
Identities = 81/210 (38%), Positives = 120/210 (57%), Gaps = 26/210 (12%)
Query: 74 VCNSCGLEIVDKYLLKVNDLCWHVRCLSCSVCRTSLGRHTSCYIKDKDIFCKLDYFRRYG 133
+C C I+D+++LK D WH +CL CS C T L C+ + + ++CK D+F+R+G
Sbjct: 35 LCAGCDQHILDRFILKALDRHWHSKCLKCSDCHTPLAER--CFSRGESVYCKDDFFKRFG 92
Query: 134 TRCSRCGRHIHSTDWVRRAKGNVYHLACFACFSCKRQLSTGEEFALVEE-KVLCRVHYDC 192
T+C+ C I T VRRA+ VYHL CFAC CKRQL+TG+EF L+E+ +++C+ Y+
Sbjct: 93 TKCAACQLGIPPTQVVRRAQDFVYHLHCFACVVCKRQLATGDEFYLMEDSRLVCKADYET 152
Query: 193 MLDNLKREVENGNGISVEGALLTEQDVNHPKPAKRARTSFTADQLQVMQAQFAQDNNPDA 252
+RE E AKR RT+ TA QL+ +++ + P
Sbjct: 153 A---KQREAE--------------------ATAKRPRTTITAKQLETLKSAYNTSPKPAR 189
Query: 253 QTLQKLAERTGLSRRVIQVWFQNCRARHKK 282
++L+ TGL RV+QVWFQN RA+ K+
Sbjct: 190 HVREQLSSETGLDMRVVQVWFQNRRAKEKR 219
>gi|11641283 LIM homeobox protein 5 [Homo sapiens]
Length = 402
Score = 157 bits (396), Expect = 2e-38
Identities = 81/236 (34%), Positives = 127/236 (53%), Gaps = 31/236 (13%)
Query: 75 CNSCGLEIVDKYLLKVNDLCWHVRCLSCSVCRTSLGRHTSCYIKDKDIFCKLDYFRRYGT 134
C C I+D++LL V D WH++C+ C C+T+L C+ ++ ++CK D+FRR+GT
Sbjct: 5 CAGCERPILDRFLLNVLDRAWHIKCVQCCECKTNLSE--KCFSREGKLYCKNDFFRRFGT 62
Query: 135 RCSRCGRHIHSTDWVRRAKGNVYHLACFACFSCKRQLSTGEEFALVEE-KVLCRVHY--- 190
+C+ C + I +D VR+A+ V+HL CF C C +QLSTGEE +++E K +C+ Y
Sbjct: 63 KCAGCAQGISPSDLVRKARSKVFHLNCFTCMVCNKQLSTGEELYVIDENKFVCKDDYLSS 122
Query: 191 ------------------------DCMLDNLKREVENGNGISVEGALLTEQDVNHPKPAK 226
D + D+ K E +N E A ++ N +
Sbjct: 123 SSLKEGSLNSVSSCTDRSLSPDLQDALQDDPK-ETDNSTSSDKETANNENEEQNSGTKRR 181
Query: 227 RARTSFTADQLQVMQAQFAQDNNPDAQTLQKLAERTGLSRRVIQVWFQNCRARHKK 282
RT+ A QL+ ++A FA P ++LA+ TGL+ RVIQVWFQN R++ ++
Sbjct: 182 GPRTTIKAKQLETLKAAFAATPKPTRHIREQLAQETGLNMRVIQVWFQNRRSKERR 237
>gi|15375314 LIM homeobox protein 4 [Homo sapiens]
Length = 390
Score = 152 bits (384), Expect = 4e-37
Identities = 77/209 (36%), Positives = 117/209 (55%), Gaps = 25/209 (11%)
Query: 75 CNSCGLEIVDKYLLKVNDLCWHVRCLSCSVCRTSLGRHTSCYIKDKDIFCKLDYFRRYGT 134
C C I+DK++LKV D WH CL C+ C+ L C+ + ++CK D+F+R+GT
Sbjct: 30 CAGCNQHILDKFILKVLDRHWHSSCLKCADCQMQLADR--CFSRAGSVYCKEDFFKRFGT 87
Query: 135 RCSRCGRHIHSTDWVRRAKGNVYHLACFACFSCKRQLSTGEEFALVEE-KVLCRVHYDCM 193
+C+ C + I T VR+A+ VYHL CFAC C RQL+TG+EF L+E+ +++C+ Y+
Sbjct: 88 KCTACQQGIPPTQVVRKAQDFVYHLHCFACIICNRQLATGDEFYLMEDGRLVCKEDYE-- 145
Query: 194 LDNLKREVENGNGISVEGALLTEQDVNHPKPAKRARTSFTADQLQVMQAQFAQDNNPDAQ 253
+Q+ + AKR RT+ TA QL+ ++ + P
Sbjct: 146 --------------------TAKQNDDSEAGAKRPRTTITAKQLETLKNAYKNSPKPARH 185
Query: 254 TLQKLAERTGLSRRVIQVWFQNCRARHKK 282
++L+ TGL RV+QVWFQN RA+ K+
Sbjct: 186 VREQLSSETGLDMRVVQVWFQNRRAKEKR 214
>gi|30410785 LIM homeobox protein 1 [Homo sapiens]
Length = 406
Score = 149 bits (377), Expect = 3e-36
Identities = 81/237 (34%), Positives = 123/237 (51%), Gaps = 32/237 (13%)
Query: 75 CNSCGLEIVDKYLLKVNDLCWHVRCLSCSVCRTSLGRHTSCYIKDKDIFCKLDYFRRYGT 134
C C I+D++LL V D WHV+C+ C C+ +L C+ ++ ++CK D+FR +GT
Sbjct: 4 CAGCKRPILDRFLLNVLDRAWHVKCVQCCECKCNLTE--KCFSREGKLYCKNDFFRCFGT 61
Query: 135 RCSRCGRHIHSTDWVRRAKGNVYHLACFACFSCKRQLSTGEEFALVEE-KVLCRVHY--- 190
+C+ C + I +D VRRA+ V+HL CF C C +QLSTGEE +++E K +C+ Y
Sbjct: 62 KCAGCAQGISPSDLVRRARSKVFHLNCFTCMMCNKQLSTGEELYIIDENKFVCKEDYLSN 121
Query: 191 -------------------------DCMLDNLKREVENGNGISVEGALLTEQDVNHPKPA 225
D D+ K + E+ N E D N
Sbjct: 122 SSVAKENSLHSATTGSDPSLSPDSQDPSQDDAK-DSESANVSDKEAGSNENDDQNLGAKR 180
Query: 226 KRARTSFTADQLQVMQAQFAQDNNPDAQTLQKLAERTGLSRRVIQVWFQNCRARHKK 282
+ RT+ A QL+ ++A FA P ++LA+ TGL+ RVIQVWFQN R++ ++
Sbjct: 181 RGPRTTIKAKQLETLKAAFAATPKPTRHIREQLAQETGLNMRVIQVWFQNRRSKERR 237
>gi|5803072 LIM domain only 4 [Homo sapiens]
Length = 165
Score = 110 bits (274), Expect = 3e-24
Identities = 51/115 (44%), Positives = 68/115 (59%), Gaps = 3/115 (2%)
Query: 75 CNSCGLEIVDKYLLKVNDLCWHVRCLSCSVCRTSLGR-HTSCYIKDKDIFCKLDYFRRYG 133
C CG +I D++LL D WH RCL CS C+ LG TSCY K I C+ DY R +G
Sbjct: 23 CAGCGGKIADRFLLYAMDSYWHSRCLKCSCCQAQLGDIGTSCYTKSGMILCRNDYIRLFG 82
Query: 134 TR--CSRCGRHIHSTDWVRRAKGNVYHLACFACFSCKRQLSTGEEFALVEEKVLC 186
CS CG+ I +++ V RA+GNVYHL CF C +C+ +L G+ F + + C
Sbjct: 83 NSGACSACGQSIPASELVMRAQGNVYHLKCFTCSTCRNRLVPGDRFHYINGSLFC 137
Score = 33.9 bits (76), Expect = 0.23
Identities = 14/54 (25%), Positives = 28/54 (51%), Gaps = 1/54 (1%)
Query: 75 CNSCGLEI-VDKYLLKVNDLCWHVRCLSCSVCRTSLGRHTSCYIKDKDIFCKLD 127
C++CG I + +++ +H++C +CS CR L + + +FC+ D
Sbjct: 87 CSACGQSIPASELVMRAQGNVYHLKCFTCSTCRNRLVPGDRFHYINGSLFCEHD 140
>gi|4505005 LIM domain only 1 [Homo sapiens]
Length = 156
Score = 100 bits (250), Expect = 2e-21
Identities = 48/120 (40%), Positives = 68/120 (56%), Gaps = 3/120 (2%)
Query: 75 CNSCGLEIVDKYLLKVNDLCWHVRCLSCSVCRTSLGR-HTSCYIKDKDIFCKLDYFRRYG 133
C C +I D+YLLK D WH CL C+ C LG ++ Y K I C+ DY R +G
Sbjct: 24 CAGCNRKIKDRYLLKALDKYWHEDCLKCACCDCRLGEVGSTLYTKANLILCRRDYLRLFG 83
Query: 134 T--RCSRCGRHIHSTDWVRRAKGNVYHLACFACFSCKRQLSTGEEFALVEEKVLCRVHYD 191
T C+ C + I + + V RA+ NVYHL CFAC C ++ G++F L +LC++ Y+
Sbjct: 84 TTGNCAACSKLIPAFEMVMRARDNVYHLDCFACQLCNQRFCVGDKFFLKNNMILCQMDYE 143
>gi|21361802 LIM domain only 3 [Homo sapiens]
Length = 145
Score = 99.8 bits (247), Expect = 3e-21
Identities = 48/120 (40%), Positives = 66/120 (55%), Gaps = 3/120 (2%)
Query: 75 CNSCGLEIVDKYLLKVNDLCWHVRCLSCSVCRTSLGR-HTSCYIKDKDIFCKLDYFRRYG 133
C C +I D+YLLK D WH CL C+ C LG ++ Y K I C+ DY R +G
Sbjct: 13 CAGCNRKIKDRYLLKALDKYWHEDCLKCACCDCRLGEVGSTLYTKANLILCRRDYLRLFG 72
Query: 134 T--RCSRCGRHIHSTDWVRRAKGNVYHLACFACFSCKRQLSTGEEFALVEEKVLCRVHYD 191
C+ C + I + + V RAK NVYHL CFAC C ++ G++F L +LC+ Y+
Sbjct: 73 VTGNCAACSKLIPAFEMVMRAKDNVYHLDCFACQLCNQRFCVGDKFFLKNNMILCQTDYE 132
>gi|47778935 LIM domain only 3 [Homo sapiens]
Length = 145
Score = 99.8 bits (247), Expect = 3e-21
Identities = 48/120 (40%), Positives = 66/120 (55%), Gaps = 3/120 (2%)
Query: 75 CNSCGLEIVDKYLLKVNDLCWHVRCLSCSVCRTSLGR-HTSCYIKDKDIFCKLDYFRRYG 133
C C +I D+YLLK D WH CL C+ C LG ++ Y K I C+ DY R +G
Sbjct: 13 CAGCNRKIKDRYLLKALDKYWHEDCLKCACCDCRLGEVGSTLYTKANLILCRRDYLRLFG 72
Query: 134 T--RCSRCGRHIHSTDWVRRAKGNVYHLACFACFSCKRQLSTGEEFALVEEKVLCRVHYD 191
C+ C + I + + V RAK NVYHL CFAC C ++ G++F L +LC+ Y+
Sbjct: 73 VTGNCAACSKLIPAFEMVMRAKDNVYHLDCFACQLCNQRFCVGDKFFLKNNMILCQTDYE 132
>gi|214832074 LIM domain only 2 isoform 1 [Homo sapiens]
Length = 227
Score = 94.7 bits (234), Expect = 1e-19
Identities = 55/182 (30%), Positives = 76/182 (41%), Gaps = 24/182 (13%)
Query: 29 GAGEEGLVSPEG----AGDEDSCSSSAPLSPSSSPRSMASGS-----------------G 67
G G G +PEG A + + AP P + P S S +
Sbjct: 32 GGGGGGARAPEGVRAPAAGQPRATKGAPPPPGTPPPSPMSSAIERKSLDPSEEPVDEVLQ 91
Query: 68 CPPGKCVCNSCGLEIVDKYLLKVNDLCWHVRCLSCSVCRTSLGR-HTSCYIKDKDIFCKL 126
PP C C I D+Y LK D WH CLSC +C LG Y K C+
Sbjct: 92 IPPSLLTCGGCQQNIGDRYFLKAIDQYWHEDCLSCDLCGCRLGEVGRRLYYKLGRKLCRR 151
Query: 127 DYFRRYGTR--CSRCGRHIHSTDWVRRAKGNVYHLACFACFSCKRQLSTGEEFALVEEKV 184
DY R +G C+ C + I + + R K VYHL CF C +C++ G+ + L+ +
Sbjct: 152 DYLRLFGQDGLCASCDKRIRAYEMTMRVKDKVYHLECFKCAACQKHFCVGDRYLLINSDI 211
Query: 185 LC 186
+C
Sbjct: 212 VC 213
>gi|214832219 LIM domain only 2 isoform 2 [Homo sapiens]
Length = 158
Score = 90.1 bits (222), Expect = 3e-18
Identities = 42/121 (34%), Positives = 58/121 (47%), Gaps = 3/121 (2%)
Query: 69 PPGKCVCNSCGLEIVDKYLLKVNDLCWHVRCLSCSVCRTSLGR-HTSCYIKDKDIFCKLD 127
PP C C I D+Y LK D WH CLSC +C LG Y K C+ D
Sbjct: 24 PPSLLTCGGCQQNIGDRYFLKAIDQYWHEDCLSCDLCGCRLGEVGRRLYYKLGRKLCRRD 83
Query: 128 YFRRYGTR--CSRCGRHIHSTDWVRRAKGNVYHLACFACFSCKRQLSTGEEFALVEEKVL 185
Y R +G C+ C + I + + R K VYHL CF C +C++ G+ + L+ ++
Sbjct: 84 YLRLFGQDGLCASCDKRIRAYEMTMRVKDKVYHLECFKCAACQKHFCVGDRYLLINSDIV 143
Query: 186 C 186
C
Sbjct: 144 C 144
>gi|214832121 LIM domain only 2 isoform 2 [Homo sapiens]
Length = 158
Score = 90.1 bits (222), Expect = 3e-18
Identities = 42/121 (34%), Positives = 58/121 (47%), Gaps = 3/121 (2%)
Query: 69 PPGKCVCNSCGLEIVDKYLLKVNDLCWHVRCLSCSVCRTSLGR-HTSCYIKDKDIFCKLD 127
PP C C I D+Y LK D WH CLSC +C LG Y K C+ D
Sbjct: 24 PPSLLTCGGCQQNIGDRYFLKAIDQYWHEDCLSCDLCGCRLGEVGRRLYYKLGRKLCRRD 83
Query: 128 YFRRYGTR--CSRCGRHIHSTDWVRRAKGNVYHLACFACFSCKRQLSTGEEFALVEEKVL 185
Y R +G C+ C + I + + R K VYHL CF C +C++ G+ + L+ ++
Sbjct: 84 YLRLFGQDGLCASCDKRIRAYEMTMRVKDKVYHLECFKCAACQKHFCVGDRYLLINSDIV 143
Query: 186 C 186
C
Sbjct: 144 C 144
>gi|51173715 actin-binding LIM protein 1 isoform c [Homo sapiens]
Length = 746
Score = 77.8 bits (190), Expect = 1e-14
Identities = 44/131 (33%), Positives = 61/131 (46%), Gaps = 4/131 (3%)
Query: 75 CNSCGLEIVDKYLLKVNDLCWHVRCLSCSVCRTSLGRHTSCYIKDKDIFCKLDYFRRYGT 134
C+ CG E +L+V +H++C +C VC L + +IK+ + C LDY R YGT
Sbjct: 39 CHKCG-EPCKGEVLRVQTKHFHIKCFTCKVCGCDLAQG-GFFIKNGEYLCTLDYQRMYGT 96
Query: 135 RCSRCGRHIHSTDWVRRAKGNVYHLACFACFSCKRQLSTGEEFALVEEKVLCRVHYDCML 194
RC CG + V A G YH CFAC CKR G+ LC++ M
Sbjct: 97 RCHGCGEFVEGE--VVTALGKTYHPNCFACTICKRPFPPGDRVTFNGRDCLCQLCAQPMS 154
Query: 195 DNLKREVENGN 205
+ K + N
Sbjct: 155 SSPKETTFSSN 165
Score = 62.0 bits (149), Expect = 8e-10
Identities = 45/138 (32%), Positives = 56/138 (40%), Gaps = 16/138 (11%)
Query: 56 SSSPRSMASGSGCPPGKCVCNSCGLEIVDKYLLKVNDLCWHVRCLSCSVCRTSLGRHTSC 115
SSSP+ S C CG +I + L D WH+ C C C L T
Sbjct: 154 SSSPKETTFSSNCA-------GCGRDIKNGQALLALDKQWHLGCFKCKSCGKVL---TGE 203
Query: 116 YI-KDKDIFCKLDYFRRYGTRCSRCGRHIHSTDWVRRAKGNVYHLACFACFSCKRQLSTG 174
YI KD +C+ DY +G +C C H T V A YH +C C C + + G
Sbjct: 204 YISKDGAPYCEKDYQGLFGVKCEAC--HQFITGKVLEAGDKHYHPSCARCSRCNQMFTEG 261
Query: 175 EEFALVEEKVLCRVHYDC 192
EE L V H DC
Sbjct: 262 EEMYLQGSTVW---HPDC 276
>gi|51173713 actin-binding LIM protein 1 isoform b [Homo sapiens]
Length = 718
Score = 77.8 bits (190), Expect = 1e-14
Identities = 44/131 (33%), Positives = 61/131 (46%), Gaps = 4/131 (3%)
Query: 75 CNSCGLEIVDKYLLKVNDLCWHVRCLSCSVCRTSLGRHTSCYIKDKDIFCKLDYFRRYGT 134
C+ CG E +L+V +H++C +C VC L + +IK+ + C LDY R YGT
Sbjct: 39 CHKCG-EPCKGEVLRVQTKHFHIKCFTCKVCGCDLAQG-GFFIKNGEYLCTLDYQRMYGT 96
Query: 135 RCSRCGRHIHSTDWVRRAKGNVYHLACFACFSCKRQLSTGEEFALVEEKVLCRVHYDCML 194
RC CG + V A G YH CFAC CKR G+ LC++ M
Sbjct: 97 RCHGCGEFVEGE--VVTALGKTYHPNCFACTICKRPFPPGDRVTFNGRDCLCQLCAQPMS 154
Query: 195 DNLKREVENGN 205
+ K + N
Sbjct: 155 SSPKETTFSSN 165
Score = 62.0 bits (149), Expect = 8e-10
Identities = 45/138 (32%), Positives = 56/138 (40%), Gaps = 16/138 (11%)
Query: 56 SSSPRSMASGSGCPPGKCVCNSCGLEIVDKYLLKVNDLCWHVRCLSCSVCRTSLGRHTSC 115
SSSP+ S C CG +I + L D WH+ C C C L T
Sbjct: 154 SSSPKETTFSSNCA-------GCGRDIKNGQALLALDKQWHLGCFKCKSCGKVL---TGE 203
Query: 116 YI-KDKDIFCKLDYFRRYGTRCSRCGRHIHSTDWVRRAKGNVYHLACFACFSCKRQLSTG 174
YI KD +C+ DY +G +C C H T V A YH +C C C + + G
Sbjct: 204 YISKDGAPYCEKDYQGLFGVKCEAC--HQFITGKVLEAGDKHYHPSCARCSRCNQMFTEG 261
Query: 175 EEFALVEEKVLCRVHYDC 192
EE L V H DC
Sbjct: 262 EEMYLQGSTVW---HPDC 276
>gi|51173711 actin-binding LIM protein 1 isoform a [Homo sapiens]
Length = 778
Score = 77.8 bits (190), Expect = 1e-14
Identities = 44/131 (33%), Positives = 61/131 (46%), Gaps = 4/131 (3%)
Query: 75 CNSCGLEIVDKYLLKVNDLCWHVRCLSCSVCRTSLGRHTSCYIKDKDIFCKLDYFRRYGT 134
C+ CG E +L+V +H++C +C VC L + +IK+ + C LDY R YGT
Sbjct: 99 CHKCG-EPCKGEVLRVQTKHFHIKCFTCKVCGCDLAQG-GFFIKNGEYLCTLDYQRMYGT 156
Query: 135 RCSRCGRHIHSTDWVRRAKGNVYHLACFACFSCKRQLSTGEEFALVEEKVLCRVHYDCML 194
RC CG + V A G YH CFAC CKR G+ LC++ M
Sbjct: 157 RCHGCGEFVEGE--VVTALGKTYHPNCFACTICKRPFPPGDRVTFNGRDCLCQLCAQPMS 214
Query: 195 DNLKREVENGN 205
+ K + N
Sbjct: 215 SSPKETTFSSN 225
Score = 62.0 bits (149), Expect = 8e-10
Identities = 45/138 (32%), Positives = 56/138 (40%), Gaps = 16/138 (11%)
Query: 56 SSSPRSMASGSGCPPGKCVCNSCGLEIVDKYLLKVNDLCWHVRCLSCSVCRTSLGRHTSC 115
SSSP+ S C CG +I + L D WH+ C C C L T
Sbjct: 214 SSSPKETTFSSNCA-------GCGRDIKNGQALLALDKQWHLGCFKCKSCGKVL---TGE 263
Query: 116 YI-KDKDIFCKLDYFRRYGTRCSRCGRHIHSTDWVRRAKGNVYHLACFACFSCKRQLSTG 174
YI KD +C+ DY +G +C C H T V A YH +C C C + + G
Sbjct: 264 YISKDGAPYCEKDYQGLFGVKCEAC--HQFITGKVLEAGDKHYHPSCARCSRCNQMFTEG 321
Query: 175 EEFALVEEKVLCRVHYDC 192
EE L V H DC
Sbjct: 322 EEMYLQGSTVW---HPDC 336
>gi|4505001 LIM domain kinase 1 [Homo sapiens]
Length = 647
Score = 77.0 bits (188), Expect = 2e-14
Identities = 42/112 (37%), Positives = 51/112 (45%), Gaps = 3/112 (2%)
Query: 74 VCNSCGLEIVDKYLLKVNDLCWHVRCLSCSVCRTSLGRHTSCYIKDKDIFCKLDYFRRYG 133
VC SCG I D L+ + WH C C C SL Y KD +FCK DY+ RYG
Sbjct: 24 VCASCGQRIYDGQYLQALNADWHADCFRCCDCSASLSHQY--YEKDGQLFCKKDYWARYG 81
Query: 134 TRCSRCGRHIHSTDWVRRAKGNVYHLACFACFSCKRQLSTGEEFALVEEKVL 185
C C I + V A YH CF C +C + G+ + LVE L
Sbjct: 82 ESCHGCSEQI-TKGLVMVAGELKYHPECFICLTCGTFIGDGDTYTLVEHSKL 132
>gi|194272207 actin binding LIM protein family, member 2 isoform 7
[Homo sapiens]
Length = 470
Score = 73.6 bits (179), Expect = 3e-13
Identities = 40/138 (28%), Positives = 62/138 (44%), Gaps = 7/138 (5%)
Query: 50 SAPLSPSSSPRSMASGSGCPPGKCVCNSCGLEIVDKYLLKVNDLCWHVRCLSCSVCRTSL 109
SA P ++P + P +CN+CG + +L+V D +H++C C C L
Sbjct: 2 SAVSQPQAAPSPLEKS---PSTAILCNTCG-NVCKGEVLRVQDKYFHIKCFVCKACGCDL 57
Query: 110 GRHTSCYIKDKDIFCKLDYFRRYGTRCSRCGRHIHSTDWVRRAKGNVYHLACFACFSCKR 169
+++ + C LDY R YGTRC C + I V A G YH CF C C+
Sbjct: 58 A-EGGFFVRQGEYICTLDYQRLYGTRCFSCDQFIEGE--VVSALGKTYHPDCFVCAVCRL 114
Query: 170 QLSTGEEFALVEEKVLCR 187
G+ ++ +C+
Sbjct: 115 PFPPGDRVTFNGKECMCQ 132
Score = 68.2 bits (165), Expect = 1e-11
Identities = 42/124 (33%), Positives = 55/124 (44%), Gaps = 6/124 (4%)
Query: 57 SSPRSMASGSGCPPGKCVCNSCGLEIVDKYLLKVNDLCWHVRCLSCSVCRTSLGRHTSCY 116
S P S+ S + G C CG EI + L D WH+ C C C L Y
Sbjct: 135 SLPVSVGSSAHLSQGLRSCGGCGTEIKNGQALVALDKHWHLGCFKCKSCGKLLNAE---Y 191
Query: 117 I-KDKDIFCKLDYFRRYGTRCSRCGRHIHSTDWVRRAKGNVYHLACFACFSCKRQLSTGE 175
I KD +C+ DY ++G RC C ++I T V A YH +C C C + + GE
Sbjct: 192 ISKDGLPYCEADYHAKFGIRCDSCEKYI--TGRVLEAGEKHYHPSCALCVRCGQMFAEGE 249
Query: 176 EFAL 179
E L
Sbjct: 250 EMYL 253
>gi|153792514 actin binding LIM protein family, member 2 isoform 6
[Homo sapiens]
Length = 521
Score = 73.6 bits (179), Expect = 3e-13
Identities = 40/138 (28%), Positives = 62/138 (44%), Gaps = 7/138 (5%)
Query: 50 SAPLSPSSSPRSMASGSGCPPGKCVCNSCGLEIVDKYLLKVNDLCWHVRCLSCSVCRTSL 109
SA P ++P + P +CN+CG + +L+V D +H++C C C L
Sbjct: 2 SAVSQPQAAPSPLEKS---PSTAILCNTCG-NVCKGEVLRVQDKYFHIKCFVCKACGCDL 57
Query: 110 GRHTSCYIKDKDIFCKLDYFRRYGTRCSRCGRHIHSTDWVRRAKGNVYHLACFACFSCKR 169
+++ + C LDY R YGTRC C + I V A G YH CF C C+
Sbjct: 58 A-EGGFFVRQGEYICTLDYQRLYGTRCFSCDQFIEGE--VVSALGKTYHPDCFVCAVCRL 114
Query: 170 QLSTGEEFALVEEKVLCR 187
G+ ++ +C+
Sbjct: 115 PFPPGDRVTFNGKECMCQ 132
Score = 68.2 bits (165), Expect = 1e-11
Identities = 42/124 (33%), Positives = 55/124 (44%), Gaps = 6/124 (4%)
Query: 57 SSPRSMASGSGCPPGKCVCNSCGLEIVDKYLLKVNDLCWHVRCLSCSVCRTSLGRHTSCY 116
S P S+ S + G C CG EI + L D WH+ C C C L Y
Sbjct: 135 SLPVSVGSSAHLSQGLRSCGGCGTEIKNGQALVALDKHWHLGCFKCKSCGKLLNAE---Y 191
Query: 117 I-KDKDIFCKLDYFRRYGTRCSRCGRHIHSTDWVRRAKGNVYHLACFACFSCKRQLSTGE 175
I KD +C+ DY ++G RC C ++I T V A YH +C C C + + GE
Sbjct: 192 ISKDGLPYCEADYHAKFGIRCDSCEKYI--TGRVLEAGEKHYHPSCALCVRCGQMFAEGE 249
Query: 176 EFAL 179
E L
Sbjct: 250 EMYL 253
>gi|194272204 actin binding LIM protein family, member 2 isoform 5
[Homo sapiens]
Length = 531
Score = 73.6 bits (179), Expect = 3e-13
Identities = 40/138 (28%), Positives = 62/138 (44%), Gaps = 7/138 (5%)
Query: 50 SAPLSPSSSPRSMASGSGCPPGKCVCNSCGLEIVDKYLLKVNDLCWHVRCLSCSVCRTSL 109
SA P ++P + P +CN+CG + +L+V D +H++C C C L
Sbjct: 2 SAVSQPQAAPSPLEKS---PSTAILCNTCG-NVCKGEVLRVQDKYFHIKCFVCKACGCDL 57
Query: 110 GRHTSCYIKDKDIFCKLDYFRRYGTRCSRCGRHIHSTDWVRRAKGNVYHLACFACFSCKR 169
+++ + C LDY R YGTRC C + I V A G YH CF C C+
Sbjct: 58 A-EGGFFVRQGEYICTLDYQRLYGTRCFSCDQFIEGE--VVSALGKTYHPDCFVCAVCRL 114
Query: 170 QLSTGEEFALVEEKVLCR 187
G+ ++ +C+
Sbjct: 115 PFPPGDRVTFNGKECMCQ 132
Score = 68.2 bits (165), Expect = 1e-11
Identities = 42/124 (33%), Positives = 55/124 (44%), Gaps = 6/124 (4%)
Query: 57 SSPRSMASGSGCPPGKCVCNSCGLEIVDKYLLKVNDLCWHVRCLSCSVCRTSLGRHTSCY 116
S P S+ S + G C CG EI + L D WH+ C C C L Y
Sbjct: 135 SLPVSVGSSAHLSQGLRSCGGCGTEIKNGQALVALDKHWHLGCFKCKSCGKLLNAE---Y 191
Query: 117 I-KDKDIFCKLDYFRRYGTRCSRCGRHIHSTDWVRRAKGNVYHLACFACFSCKRQLSTGE 175
I KD +C+ DY ++G RC C ++I T V A YH +C C C + + GE
Sbjct: 192 ISKDGLPYCEADYHAKFGIRCDSCEKYI--TGRVLEAGEKHYHPSCALCVRCGQMFAEGE 249
Query: 176 EFAL 179
E L
Sbjct: 250 EMYL 253
>gi|194272202 actin binding LIM protein family, member 2 isoform 4
[Homo sapiens]
Length = 559
Score = 73.6 bits (179), Expect = 3e-13
Identities = 40/138 (28%), Positives = 62/138 (44%), Gaps = 7/138 (5%)
Query: 50 SAPLSPSSSPRSMASGSGCPPGKCVCNSCGLEIVDKYLLKVNDLCWHVRCLSCSVCRTSL 109
SA P ++P + P +CN+CG + +L+V D +H++C C C L
Sbjct: 2 SAVSQPQAAPSPLEKS---PSTAILCNTCG-NVCKGEVLRVQDKYFHIKCFVCKACGCDL 57
Query: 110 GRHTSCYIKDKDIFCKLDYFRRYGTRCSRCGRHIHSTDWVRRAKGNVYHLACFACFSCKR 169
+++ + C LDY R YGTRC C + I V A G YH CF C C+
Sbjct: 58 A-EGGFFVRQGEYICTLDYQRLYGTRCFSCDQFIEGE--VVSALGKTYHPDCFVCAVCRL 114
Query: 170 QLSTGEEFALVEEKVLCR 187
G+ ++ +C+
Sbjct: 115 PFPPGDRVTFNGKECMCQ 132
Score = 68.2 bits (165), Expect = 1e-11
Identities = 42/124 (33%), Positives = 55/124 (44%), Gaps = 6/124 (4%)
Query: 57 SSPRSMASGSGCPPGKCVCNSCGLEIVDKYLLKVNDLCWHVRCLSCSVCRTSLGRHTSCY 116
S P S+ S + G C CG EI + L D WH+ C C C L Y
Sbjct: 135 SLPVSVGSSAHLSQGLRSCGGCGTEIKNGQALVALDKHWHLGCFKCKSCGKLLNAE---Y 191
Query: 117 I-KDKDIFCKLDYFRRYGTRCSRCGRHIHSTDWVRRAKGNVYHLACFACFSCKRQLSTGE 175
I KD +C+ DY ++G RC C ++I T V A YH +C C C + + GE
Sbjct: 192 ISKDGLPYCEADYHAKFGIRCDSCEKYI--TGRVLEAGEKHYHPSCALCVRCGQMFAEGE 249
Query: 176 EFAL 179
E L
Sbjct: 250 EMYL 253
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.320 0.132 0.414
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 15,873,437
Number of Sequences: 37866
Number of extensions: 834160
Number of successful extensions: 5068
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 320
Number of HSP's successfully gapped in prelim test: 124
Number of HSP's that attempted gapping in prelim test: 4208
Number of HSP's gapped (non-prelim): 694
length of query: 356
length of database: 18,247,518
effective HSP length: 103
effective length of query: 253
effective length of database: 14,347,320
effective search space: 3629871960
effective search space used: 3629871960
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.