BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|49472835 bridging integrator 2 [Homo sapiens] (565 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|49472835 bridging integrator 2 [Homo sapiens] 1105 0.0 gi|21536409 bridging integrator 1 isoform 5 [Homo sapiens] 331 9e-91 gi|21536413 bridging integrator 1 isoform 7 [Homo sapiens] 318 1e-86 gi|21536411 bridging integrator 1 isoform 6 [Homo sapiens] 316 4e-86 gi|21536402 bridging integrator 1 isoform 2 [Homo sapiens] 316 4e-86 gi|21536407 bridging integrator 1 isoform 4 [Homo sapiens] 314 1e-85 gi|21536400 bridging integrator 1 isoform 1 [Homo sapiens] 313 3e-85 gi|21536415 bridging integrator 1 isoform 9 [Homo sapiens] 311 1e-84 gi|21536417 bridging integrator 1 isoform 10 [Homo sapiens] 308 7e-84 gi|4757748 bridging integrator 1 isoform 8 [Homo sapiens] 308 1e-83 gi|4502081 amphiphysin isoform 1 [Homo sapiens] 302 5e-82 gi|21536404 bridging integrator 1 isoform 3 [Homo sapiens] 301 8e-82 gi|21536423 amphiphysin isoform 2 [Homo sapiens] 296 3e-80 gi|42542379 serine/arginine repetitive matrix 1 [Homo sapiens] 71 2e-12 gi|157738649 neurofilament, medium polypeptide 150kDa isoform 1 ... 67 4e-11 gi|8923904 bridging integrator 3 [Homo sapiens] 62 1e-09 gi|55741677 SET domain containing 1A [Homo sapiens] 62 1e-09 gi|189181720 proteoglycan 4 isoform B [Homo sapiens] 62 2e-09 gi|67190163 proteoglycan 4 isoform A [Homo sapiens] 62 2e-09 gi|189181724 proteoglycan 4 isoform D [Homo sapiens] 61 2e-09 gi|189181722 proteoglycan 4 isoform C [Homo sapiens] 61 2e-09 gi|116284392 mucin 2 precursor [Homo sapiens] 60 7e-09 gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens] 60 7e-09 gi|117414137 retinitis pigmentosa 1-like 1 [Homo sapiens] 59 1e-08 gi|21312134 mediator complex subunit 15 isoform b [Homo sapiens] 58 2e-08 gi|163965366 nascent polypeptide-associated complex alpha subuni... 58 2e-08 gi|39930351 dynamin binding protein [Homo sapiens] 57 6e-08 gi|239740773 PREDICTED: similar to diffuse panbronchiolitis crit... 56 8e-08 gi|20143482 melanoma antigen family E, 1 [Homo sapiens] 56 1e-07 gi|239751395 PREDICTED: hypothetical protein, partial [Homo sapi... 55 2e-07 >gi|49472835 bridging integrator 2 [Homo sapiens] Length = 565 Score = 1105 bits (2859), Expect = 0.0 Identities = 565/565 (100%), Positives = 565/565 (100%) Query: 1 MAEGKAGGAAGLFAKQVQKKFSRAQEKVLQKLGKAVETKDERFEQSASNFYQQQAEGHKL 60 MAEGKAGGAAGLFAKQVQKKFSRAQEKVLQKLGKAVETKDERFEQSASNFYQQQAEGHKL Sbjct: 1 MAEGKAGGAAGLFAKQVQKKFSRAQEKVLQKLGKAVETKDERFEQSASNFYQQQAEGHKL 60 Query: 61 YKDLKNFLSAVKVMHESSKRVSETLQEIYSSEWDGHEELKAIVWNNDLLWEDYEEKLADQ 120 YKDLKNFLSAVKVMHESSKRVSETLQEIYSSEWDGHEELKAIVWNNDLLWEDYEEKLADQ Sbjct: 61 YKDLKNFLSAVKVMHESSKRVSETLQEIYSSEWDGHEELKAIVWNNDLLWEDYEEKLADQ 120 Query: 121 AVRTMEIYVAQFSEIKERIAKRGRKLVDYDSARHHLEAVQNAKKKDEAKTAKAEEEFNKA 180 AVRTMEIYVAQFSEIKERIAKRGRKLVDYDSARHHLEAVQNAKKKDEAKTAKAEEEFNKA Sbjct: 121 AVRTMEIYVAQFSEIKERIAKRGRKLVDYDSARHHLEAVQNAKKKDEAKTAKAEEEFNKA 180 Query: 181 QTVFEDLNQELLEELPILYNSRIGCYVTIFQNISNLRDVFYREMSKLNHNLYEVMSKLEK 240 QTVFEDLNQELLEELPILYNSRIGCYVTIFQNISNLRDVFYREMSKLNHNLYEVMSKLEK Sbjct: 181 QTVFEDLNQELLEELPILYNSRIGCYVTIFQNISNLRDVFYREMSKLNHNLYEVMSKLEK 240 Query: 241 QHSNKVFVVKGLSSSSRRSLVISPPVRTATVSSPLTSPTSPSTLSLKSESESVSATEDLA 300 QHSNKVFVVKGLSSSSRRSLVISPPVRTATVSSPLTSPTSPSTLSLKSESESVSATEDLA Sbjct: 241 QHSNKVFVVKGLSSSSRRSLVISPPVRTATVSSPLTSPTSPSTLSLKSESESVSATEDLA 300 Query: 301 PDAAQGEDNSEIKELLEEEEIEKEGSEASSSEEDEPLPACNGPAQAQPSPTTERAKSQEE 360 PDAAQGEDNSEIKELLEEEEIEKEGSEASSSEEDEPLPACNGPAQAQPSPTTERAKSQEE Sbjct: 301 PDAAQGEDNSEIKELLEEEEIEKEGSEASSSEEDEPLPACNGPAQAQPSPTTERAKSQEE 360 Query: 361 VLPSSTTPSPGGALSPSGQPSSSATEVVLRTRTASEGSEQPKKRASIQRTSAPPSRPPPP 420 VLPSSTTPSPGGALSPSGQPSSSATEVVLRTRTASEGSEQPKKRASIQRTSAPPSRPPPP Sbjct: 361 VLPSSTTPSPGGALSPSGQPSSSATEVVLRTRTASEGSEQPKKRASIQRTSAPPSRPPPP 420 Query: 421 RATASPRPSSGNIPSSPTASGGGSPTSPRASLGTGTASPRTSLEVSPNPEPPEKPVRTPE 480 RATASPRPSSGNIPSSPTASGGGSPTSPRASLGTGTASPRTSLEVSPNPEPPEKPVRTPE Sbjct: 421 RATASPRPSSGNIPSSPTASGGGSPTSPRASLGTGTASPRTSLEVSPNPEPPEKPVRTPE 480 Query: 481 AKENENIHNQNPEELCTSPTLMTSQVASEPGEAKKMEDKEKDNKLISANSSEGQDQLQVS 540 AKENENIHNQNPEELCTSPTLMTSQVASEPGEAKKMEDKEKDNKLISANSSEGQDQLQVS Sbjct: 481 AKENENIHNQNPEELCTSPTLMTSQVASEPGEAKKMEDKEKDNKLISANSSEGQDQLQVS 540 Query: 541 MVPENNNLTAPEPQEEVSTSENPQL 565 MVPENNNLTAPEPQEEVSTSENPQL Sbjct: 541 MVPENNNLTAPEPQEEVSTSENPQL 565 >gi|21536409 bridging integrator 1 isoform 5 [Homo sapiens] Length = 518 Score = 331 bits (849), Expect = 9e-91 Identities = 195/453 (43%), Positives = 260/453 (57%), Gaps = 54/453 (11%) Query: 1 MAE-GKAGGAAGLFAKQVQKKFSRAQEKVLQKLGKAVETKDERFEQSASNFYQQQAEGHK 59 MAE G G AG A VQKK +RAQEKVLQKLGKA ETKDE+FEQ NF +Q EG + Sbjct: 1 MAEMGSKGVTAGKIASNVQKKLTRAQEKVLQKLGKADETKDEQFEQCVQNFNKQLTEGTR 60 Query: 60 LYKDLKNFLSAVKVMHESSKRVSETLQEIYSSEWDGHEELKAIVWNNDLLWEDYEEKLAD 119 L KDL+ +L++VK MHE+SK+++E LQE+Y +W G +E I NNDLLW DY +KL D Sbjct: 61 LQKDLRTYLASVKAMHEASKKLNECLQEVYEPDWPGRDEANKIAENNDLLWMDYHQKLVD 120 Query: 120 QAVRTMEIYVAQFSEIKERIAKRGRKLVDYDSARHHLEAVQNAKKKDEAKTAKAEEEFNK 179 QA+ TM+ Y+ QF +IK RIAKRGRKLVDYDSARHH E++Q AKKKDEAK AKAEEE K Sbjct: 121 QALLTMDTYLGQFPDIKSRIAKRGRKLVDYDSARHHYESLQTAKKKDEAKIAKAEEELIK 180 Query: 180 AQTVFEDLNQELLEELPILYNSRIGCYVTIFQNISNLRDVFYREMSKLNHNLYEVMSKLE 239 AQ VFE++N +L EELP L+NSR+G YV FQ+I+ L + F++EMSKLN NL +V+ LE Sbjct: 181 AQKVFEEMNVDLQEELPSLWNSRVGFYVNTFQSIAGLEENFHKEMSKLNQNLNDVLVGLE 240 Query: 240 KQHSNKVFVVKGLSSSSRRSLVISPPVRTATVSSPLTSPTSPSTLSLKSESESVSATEDL 299 KQH + F VK S + +P + S P SP + + + E E Sbjct: 241 KQHGSNTFTVKAQPSDN------APAKGNKSPSPPDGSPAATPEIRVNHEPEPAGGA--- 291 Query: 300 APDAAQGEDNSEIKELLEEEEIEKEGSEASSSEEDEPLPACNGPAQAQPSPTTERAKSQE 359 P A + S++++ P P T + QE Sbjct: 292 TPGATLPKSPSQLRK--------------------------GPPVPPPPKHTPSKEVKQE 325 Query: 360 EVL---------------PSSTTPSPGGALSPSGQPSSS--ATEVVLRTRTASEGSEQPK 402 ++L PS T SP G+L PSG+PS++ V ++TA G QP Sbjct: 326 QILSLFEDTFVPEISVTTPSQPTESPAGSL-PSGEPSAAEGTFAVSWPSQTAEPGPAQPA 384 Query: 403 KRASIQRTSAPPSRPPPPRATASPRPSSGNIPS 435 + + + + P + P TA+ +S ++P+ Sbjct: 385 EASEVAGGTQPAAGAQEPGETAASEAASSSLPA 417 Score = 36.2 bits (82), Expect = 0.082 Identities = 48/179 (26%), Positives = 63/179 (35%), Gaps = 37/179 (20%) Query: 318 EEEIEKEGSEASSSEEDEPLPACNGPAQAQPSPTTERAKSQEEVLPSSTTPSPGGALSPS 377 EE KE S+ + + D + + Q T K+Q PS P+ G SPS Sbjct: 218 EENFHKEMSKLNQNLNDVLVGL-----EKQHGSNTFTVKAQ----PSDNAPAKGNK-SPS 267 Query: 378 GQPSSSATEVVLRTRT-------ASEGSEQPKKRASIQRTSAPPSRPPPPRATASPRPSS 430 S A +R A+ G+ PK + +++ P PPPP+ T S Sbjct: 268 PPDGSPAATPEIRVNHEPEPAGGATPGATLPKSPSQLRKG---PPVPPPPKHTPSKEVKQ 324 Query: 431 GNI----------------PSSPTASGGGSPTSPRASLGTGT-ASPRTSLEVSPNPEPP 472 I PS PT S GS S S GT A S P P P Sbjct: 325 EQILSLFEDTFVPEISVTTPSQPTESPAGSLPSGEPSAAEGTFAVSWPSQTAEPGPAQP 383 >gi|21536413 bridging integrator 1 isoform 7 [Homo sapiens] Length = 475 Score = 318 bits (814), Expect = 1e-86 Identities = 191/400 (47%), Positives = 243/400 (60%), Gaps = 22/400 (5%) Query: 1 MAE-GKAGGAAGLFAKQVQKKFSRAQEKVLQKLGKAVETKDERFEQSASNFYQQQAEGHK 59 MAE G G AG A VQKK +RAQEKVLQKLGKA ETKDE+FEQ NF +Q EG + Sbjct: 1 MAEMGSKGVTAGKIASNVQKKLTRAQEKVLQKLGKADETKDEQFEQCVQNFNKQLTEGTR 60 Query: 60 LYKDLKNFLSAVKVMHESSKRVSETLQEIYSSEWDGHEELKAIVWNNDLLWEDYEEKLAD 119 L KDL+ +L++VK MHE+SK+++E LQE+Y +W G +E I NNDLLW DY +KL D Sbjct: 61 LQKDLRTYLASVKAMHEASKKLNECLQEVYEPDWPGRDEANKIAENNDLLWMDYHQKLVD 120 Query: 120 QAVRTMEIYVAQFSEIKERIAKRGRKLVDYDSARHHLEAVQNAKKKDEAKTAKAEEEFNK 179 QA+ TM+ Y+ QF +IK RIAKRGRKLVDYDSARHH E++Q AKKKDEAK AKAEEE K Sbjct: 121 QALLTMDTYLGQFPDIKSRIAKRGRKLVDYDSARHHYESLQTAKKKDEAKIAKAEEELIK 180 Query: 180 AQTVFEDLNQELLEELPILYNSRIGCYVTIFQNISNLRDVFYREMSKLNHNLYEVMSKLE 239 AQ VFE++N +L EELP L+NSR+G YV FQ+I+ L + F++EMSKLN NL +V+ LE Sbjct: 181 AQKVFEEMNVDLQEELPSLWNSRVGFYVNTFQSIAGLEENFHKEMSKLNQNLNDVLVGLE 240 Query: 240 KQHSNKVFVVKGLSSSSRRSLVISPPVRTATVSSPLTSPTSPSTLSLKSESESVSATEDL 299 KQH + F VK S + +P + S P SP + + + E E Sbjct: 241 KQHGSNTFTVKAQPSDN------APAKGNKSPSPPDGSPAATPEIRVNHEPEPAGGATPG 294 Query: 300 A--PDAAQGEDNSEIKELLEEEEIEKEGSEASS--SEEDEPLPACNGPAQAQPSPTTERA 355 A P + S L E EG+ A S S+ EP P AQP+ +E A Sbjct: 295 ATLPKSPSQPTESPAGSLPSGEPSAAEGTFAVSWPSQTAEPGP-------AQPAEASEVA 347 Query: 356 KSQEEVLPSSTTPSPGGALSPSGQPSSSATEVVLRTRTAS 395 + P++ P G + S SSS VV+ T A+ Sbjct: 348 GGTQ---PAAGAQEP-GETAASEAASSSLPAVVVETFPAT 383 Score = 30.0 bits (66), Expect = 5.9 Identities = 30/125 (24%), Positives = 40/125 (32%), Gaps = 18/125 (14%) Query: 400 QPKKRASIQRTSAP------PSRPPPPRATASPRPSSGNIPSSPTASGGGSPT-SPRASL 452 QP A + +P P+ P R P P+ G P + PT SP SL Sbjct: 253 QPSDNAPAKGNKSPSPPDGSPAATPEIRVNHEPEPAGGATPGATLPKSPSQPTESPAGSL 312 Query: 453 GTGTASPRTSLEVSPNPEPPEKPVRTPEAKENENIHNQNPEELCTSPTLMTSQVASEPGE 512 +G S P +P A+ +E P + A EPGE Sbjct: 313 PSGEPSAAEGTFAVSWPSQTAEPGPAQPAEASEVAGGTQP-----------AAGAQEPGE 361 Query: 513 AKKME 517 E Sbjct: 362 TAASE 366 >gi|21536411 bridging integrator 1 isoform 6 [Homo sapiens] Length = 482 Score = 316 bits (809), Expect = 4e-86 Identities = 186/405 (45%), Positives = 248/405 (61%), Gaps = 25/405 (6%) Query: 1 MAE-GKAGGAAGLFAKQVQKKFSRAQEKVLQKLGKAVETKDERFEQSASNFYQQQAEGHK 59 MAE G G AG A VQKK +RAQEKVLQKLGKA ETKDE+FEQ NF +Q EG + Sbjct: 1 MAEMGSKGVTAGKIASNVQKKLTRAQEKVLQKLGKADETKDEQFEQCVQNFNKQLTEGTR 60 Query: 60 LYKDLKNFLSAVKVMHESSKRVSETLQEIYSSEWDGHEELKAIVWNNDLLWEDYEEKLAD 119 L KDL+ +L++VK MHE+SK+++E LQE+Y +W G +E I NNDLLW DY +KL D Sbjct: 61 LQKDLRTYLASVKAMHEASKKLNECLQEVYEPDWPGRDEANKIAENNDLLWMDYHQKLVD 120 Query: 120 QAVRTMEIYVAQFSEIKERIAKRGRKLVDYDSARHHLEAVQNAKKKDEAKTAKAEEEFNK 179 QA+ TM+ Y+ QF +IK RIAKRGRKLVDYDSARHH E++Q AKKKDEAK AKAEEE K Sbjct: 121 QALLTMDTYLGQFPDIKSRIAKRGRKLVDYDSARHHYESLQTAKKKDEAKIAKAEEELIK 180 Query: 180 AQTVFEDLNQELLEELPILYNSRIGCYVTIFQNISNLRDVFYREMSKLNHNLYEVMSKLE 239 AQ VFE++N +L EELP L+NSR+G YV FQ+I+ L + F++EMSKLN NL +V+ LE Sbjct: 181 AQKVFEEMNVDLQEELPSLWNSRVGFYVNTFQSIAGLEENFHKEMSKLNQNLNDVLVGLE 240 Query: 240 KQHSNKVFVVKGLSSSSRRSLVISPPVRTATVSSPLTSPTSPSTLSLKSESESVSATEDL 299 KQH + F VK S + +P + S P SP + + + E E Sbjct: 241 KQHGSNTFTVKAQPSDN------APAKGNKSPSPPDGSPAATPEIRVNHEPEPAGGA--- 291 Query: 300 APDAAQGEDNSEIK---------ELLEEEEIEKEGSEASSSEEDEPLPACNGPAQAQPSP 350 P A + S+++ + +E+++E + S ED +P + +QP+ Sbjct: 292 TPGATLPKSPSQLRKGPPVPPPPKHTPSKEVKQE--QILSLFEDTFVPEISVTTPSQPAE 349 Query: 351 TTERAKSQEEVLPSSTTPSPGGALSPSGQPSSSATEVVLRTRTAS 395 +E A + P++ P G + S SSS VV+ T A+ Sbjct: 350 ASEVAGGTQ---PAAGAQEP-GETAASEAASSSLPAVVVETFPAT 390 >gi|21536402 bridging integrator 1 isoform 2 [Homo sapiens] Length = 550 Score = 316 bits (809), Expect = 4e-86 Identities = 198/470 (42%), Positives = 264/470 (56%), Gaps = 56/470 (11%) Query: 1 MAE-GKAGGAAGLFAKQVQKKFSRAQEKVLQKLGKAVETKDERFEQSASNFYQQQAEGHK 59 MAE G G AG A VQKK +RAQEKVLQKLGKA ETKDE+FEQ NF +Q EG + Sbjct: 1 MAEMGSKGVTAGKIASNVQKKLTRAQEKVLQKLGKADETKDEQFEQCVQNFNKQLTEGTR 60 Query: 60 LYKDLKNFLSAVKVMHESSKRVSETLQEIYSSEWDGHEELKAIVWNNDLLWEDYEEKLAD 119 L KDL+ +L++VK MHE+SK+++E LQE+Y +W G +E I NNDLLW DY +KL D Sbjct: 61 LQKDLRTYLASVKAMHEASKKLNECLQEVYEPDWPGRDEANKIAENNDLLWMDYHQKLVD 120 Query: 120 QAVRTMEIYVAQFSEIKERIAKRGRKLVDYDSARHHLEAVQNAKKKDEAKTAK------- 172 QA+ TM+ Y+ QF +IK RIAKRGRKLVDYDSARHH E++Q AKKKDEAK AK Sbjct: 121 QALLTMDTYLGQFPDIKSRIAKRGRKLVDYDSARHHYESLQTAKKKDEAKIAKPVSLLEK 180 Query: 173 ------------------------AEEEFNKAQTVFEDLNQELLEELPILYNSRIGCYVT 208 AEEE KAQ VFE++N +L EELP L+NSR+G YV Sbjct: 181 AAPQWCQGKLQAHLVAQTNLLRNQAEEELIKAQKVFEEMNVDLQEELPSLWNSRVGFYVN 240 Query: 209 IFQNISNLRDVFYREMSKLNHNLYEVMSKLEKQHSNKVFVVKGLSSSSRRSLVISPPVRT 268 FQ+I+ L + F++EMSKLN NL +V+ LEKQH + F VK S + +P Sbjct: 241 TFQSIAGLEENFHKEMSKLNQNLNDVLVGLEKQHGSNTFTVKAQPSDN------APAKGN 294 Query: 269 ATVSSPLTSPTSPSTLSLKSESESVSATEDLAPDAAQGEDNSEIKELLEEEEIEKEGSEA 328 + S P SP + + + E E P A + S+ E +A Sbjct: 295 KSPSPPDGSPAATPEIRVNHEPEPAGGA---TPGATLPKSPSQF------EAPGPFSEQA 345 Query: 329 SSSEED-EPLPACNGPAQAQPSPTTERAKSQEEVLPSSTTPSPGGALSPSGQPSSS--AT 385 S + D +PLP P +A P+P+ + T SP G+L PSG+PS++ Sbjct: 346 SLLDLDFDPLPPVTSPVKA-PTPSGQSIPWD----LWEPTESPAGSL-PSGEPSAAEGTF 399 Query: 386 EVVLRTRTASEGSEQPKKRASIQRTSAPPSRPPPPRATASPRPSSGNIPS 435 V ++TA G QP + + + + P + P TA+ +S ++P+ Sbjct: 400 AVSWPSQTAEPGPAQPAEASEVAGGTQPAAGAQEPGETAASEAASSSLPA 449 >gi|21536407 bridging integrator 1 isoform 4 [Homo sapiens] Length = 497 Score = 314 bits (805), Expect = 1e-85 Identities = 185/415 (44%), Positives = 248/415 (59%), Gaps = 26/415 (6%) Query: 1 MAE-GKAGGAAGLFAKQVQKKFSRAQEKVLQKLGKAVETKDERFEQSASNFYQQQAEGHK 59 MAE G G AG A VQKK +RAQEKVLQKLGKA ETKDE+FEQ NF +Q EG + Sbjct: 1 MAEMGSKGVTAGKIASNVQKKLTRAQEKVLQKLGKADETKDEQFEQCVQNFNKQLTEGTR 60 Query: 60 LYKDLKNFLSAVKVMHESSKRVSETLQEIYSSEWDGHEELKAIVWNNDLLWEDYEEKLAD 119 L KDL+ +L++VK MHE+SK+++E LQE+Y +W G +E I NNDLLW DY +KL D Sbjct: 61 LQKDLRTYLASVKAMHEASKKLNECLQEVYEPDWPGRDEANKIAENNDLLWMDYHQKLVD 120 Query: 120 QAVRTMEIYVAQFSEIKERIAKRGRKLVDYDSARHHLEAVQNAKKKDEAKTAKAEEEFNK 179 QA+ TM+ Y+ QF +IK RIAKRGRKLVDYDSARHH E++Q AKKKDEAK AKAEEE K Sbjct: 121 QALLTMDTYLGQFPDIKSRIAKRGRKLVDYDSARHHYESLQTAKKKDEAKIAKAEEELIK 180 Query: 180 AQTVFEDLNQELLEELPILYNSRIGCYVTIFQNISNLRDVFYREMSKLNHNLYEVMSKLE 239 AQ VFE++N +L EELP L+NSR+G YV FQ+I+ L + F++EMSKLN NL +V+ LE Sbjct: 181 AQKVFEEMNVDLQEELPSLWNSRVGFYVNTFQSIAGLEENFHKEMSKLNQNLNDVLVGLE 240 Query: 240 KQHSNKVFVVKGLSSSSRRSLVISPPVRTATVSSPLTSPTSPSTLSLKSESESVSATEDL 299 KQH + F VK + P S L K S++ A + Sbjct: 241 KQHGSNTFTVK---------------------AQPRKKSKLFSRLRRKKNSDNAPAKGNK 279 Query: 300 APDAAQGEDNSEIKELLEEEEIEKEGSEASSSEEDEPLPACNG-PAQAQPSPTTERAKSQ 358 +P G + + + E G+ ++ P G P P T + Q Sbjct: 280 SPSPPDGSPAATPEIRVNHEPEPAGGATPGATLPKSPSQLRKGPPVPPPPKHTPSKEVKQ 339 Query: 359 EEVLP-SSTTPSPGGALSPSGQPSSSATEVVLRTRTASEGSEQPKKRASIQRTSA 412 E++L T P +++ QP + A+EV T+ A+ G+++P + A+ + S+ Sbjct: 340 EQILSLFEDTFVPEISVTTPSQP-AEASEVAGGTQPAA-GAQEPGETAASEAASS 392 >gi|21536400 bridging integrator 1 isoform 1 [Homo sapiens] Length = 593 Score = 313 bits (801), Expect = 3e-85 Identities = 199/502 (39%), Positives = 275/502 (54%), Gaps = 77/502 (15%) Query: 1 MAE-GKAGGAAGLFAKQVQKKFSRAQEKVLQKLGKAVETKDERFEQSASNFYQQQAEGHK 59 MAE G G AG A VQKK +RAQEKVLQKLGKA ETKDE+FEQ NF +Q EG + Sbjct: 1 MAEMGSKGVTAGKIASNVQKKLTRAQEKVLQKLGKADETKDEQFEQCVQNFNKQLTEGTR 60 Query: 60 LYKDLKNFLSAVKVMHESSKRVSETLQEIYSSEWDGHEELKAIVWNNDLLWEDYEEKLAD 119 L KDL+ +L++VK MHE+SK+++E LQE+Y +W G +E I NNDLLW DY +KL D Sbjct: 61 LQKDLRTYLASVKAMHEASKKLNECLQEVYEPDWPGRDEANKIAENNDLLWMDYHQKLVD 120 Query: 120 QAVRTMEIYVAQFSEIKERIAKRGRKLVDYDSARHHLEAVQNAKKKDEAKTAK------- 172 QA+ TM+ Y+ QF +IK RIAKRGRKLVDYDSARHH E++Q AKKKDEAK AK Sbjct: 121 QALLTMDTYLGQFPDIKSRIAKRGRKLVDYDSARHHYESLQTAKKKDEAKIAKPVSLLEK 180 Query: 173 ------------------------AEEEFNKAQTVFEDLNQELLEELPILYNSRIGCYVT 208 AEEE KAQ VFE++N +L EELP L+NSR+G YV Sbjct: 181 AAPQWCQGKLQAHLVAQTNLLRNQAEEELIKAQKVFEEMNVDLQEELPSLWNSRVGFYVN 240 Query: 209 IFQNISNLRDVFYREMSKLNHNLYEVMSKLEKQHSNKVFVVKGLSSSSRRSLVISPPVRT 268 FQ+I+ L + F++EMSKLN NL +V+ LEKQH + F VK S + +P Sbjct: 241 TFQSIAGLEENFHKEMSKLNQNLNDVLVGLEKQHGSNTFTVKAQPSDN------APAKGN 294 Query: 269 ATVSSPLTSPTSPSTLSLKSESESVSATEDLAPDAAQGEDNSEIK---------ELLEEE 319 + S P SP + + + E E P A + S+++ + + Sbjct: 295 KSPSPPDGSPAATPEIRVNHEPEPAGGA---TPGATLPKSPSQLRKGPPVPPPPKHTPSK 351 Query: 320 EIEKEGSEASSSEEDEPLPACNGPAQAQ-PSPTTERAKSQE---EVLPSSTTP------- 368 E+++E + + P + P+Q + P P +E+A + + LP T+P Sbjct: 352 EVKQEQILSLFEDTFVPEISVTTPSQFEAPGPFSEQASLLDLDFDPLPPVTSPVKAPTPS 411 Query: 369 -------------SPGGALSPSGQPSSS--ATEVVLRTRTASEGSEQPKKRASIQRTSAP 413 SP G+L PSG+PS++ V ++TA G QP + + + + P Sbjct: 412 GQSIPWDLWEPTESPAGSL-PSGEPSAAEGTFAVSWPSQTAEPGPAQPAEASEVAGGTQP 470 Query: 414 PSRPPPPRATASPRPSSGNIPS 435 + P TA+ +S ++P+ Sbjct: 471 AAGAQEPGETAASEAASSSLPA 492 >gi|21536415 bridging integrator 1 isoform 9 [Homo sapiens] Length = 439 Score = 311 bits (796), Expect = 1e-84 Identities = 173/344 (50%), Positives = 221/344 (64%), Gaps = 11/344 (3%) Query: 1 MAE-GKAGGAAGLFAKQVQKKFSRAQEKVLQKLGKAVETKDERFEQSASNFYQQQAEGHK 59 MAE G G AG A VQKK +RAQEKVLQKLGKA ETKDE+FEQ NF +Q EG + Sbjct: 1 MAEMGSKGVTAGKIASNVQKKLTRAQEKVLQKLGKADETKDEQFEQCVQNFNKQLTEGTR 60 Query: 60 LYKDLKNFLSAVKVMHESSKRVSETLQEIYSSEWDGHEELKAIVWNNDLLWEDYEEKLAD 119 L KDL+ +L++VK MHE+SK+++E LQE+Y +W G +E I NNDLLW DY +KL D Sbjct: 61 LQKDLRTYLASVKAMHEASKKLNECLQEVYEPDWPGRDEANKIAENNDLLWMDYHQKLVD 120 Query: 120 QAVRTMEIYVAQFSEIKERIAKRGRKLVDYDSARHHLEAVQNAKKKDEAKTAKAEEEFNK 179 QA+ TM+ Y+ QF +IK RIAKRGRKLVDYDSARHH E++Q AKKKDEAK AKAEEE K Sbjct: 121 QALLTMDTYLGQFPDIKSRIAKRGRKLVDYDSARHHYESLQTAKKKDEAKIAKAEEELIK 180 Query: 180 AQTVFEDLNQELLEELPILYNSRIGCYVTIFQNISNLRDVFYREMSKLNHNLYEVMSKLE 239 AQ VFE++N +L EELP L+NSR+G YV FQ+I+ L + F++EMSKLN NL +V+ LE Sbjct: 181 AQKVFEEMNVDLQEELPSLWNSRVGFYVNTFQSIAGLEENFHKEMSKLNQNLNDVLVGLE 240 Query: 240 KQHSNKVFVVKGLSSSSRRSLVISPPVRTATVSSPLTSPTSPSTLSLKSESESVSAT--- 296 KQH + F VK S + +P + S P SP + + + E E Sbjct: 241 KQHGSNTFTVKAQPSDN------APAKGNKSPSPPDGSPAATPEIRVNHEPEPAGGATPG 294 Query: 297 EDLAPDAAQGEDNSEIKELLEEEEIEKEGSEASSSE-EDEPLPA 339 L +Q + SE+ + +E E ++SE LPA Sbjct: 295 ATLPKSPSQPAEASEVAGGTQPAAGAQEPGETAASEAASSSLPA 338 >gi|21536417 bridging integrator 1 isoform 10 [Homo sapiens] Length = 409 Score = 308 bits (790), Expect = 7e-84 Identities = 162/292 (55%), Positives = 203/292 (69%), Gaps = 7/292 (2%) Query: 1 MAE-GKAGGAAGLFAKQVQKKFSRAQEKVLQKLGKAVETKDERFEQSASNFYQQQAEGHK 59 MAE G G AG A VQKK +RAQEKVLQKLGKA ETKDE+FEQ NF +Q EG + Sbjct: 1 MAEMGSKGVTAGKIASNVQKKLTRAQEKVLQKLGKADETKDEQFEQCVQNFNKQLTEGTR 60 Query: 60 LYKDLKNFLSAVKVMHESSKRVSETLQEIYSSEWDGHEELKAIVWNNDLLWEDYEEKLAD 119 L KDL+ +L++VK MHE+SK+++E LQE+Y +W G +E I NNDLLW DY +KL D Sbjct: 61 LQKDLRTYLASVKAMHEASKKLNECLQEVYEPDWPGRDEANKIAENNDLLWMDYHQKLVD 120 Query: 120 QAVRTMEIYVAQFSEIKERIAKRGRKLVDYDSARHHLEAVQNAKKKDEAKTAKAEEEFNK 179 QA+ TM+ Y+ QF +IK RIAKRGRKLVDYDSARHH E++Q AKKKDEAK AKAEEE K Sbjct: 121 QALLTMDTYLGQFPDIKSRIAKRGRKLVDYDSARHHYESLQTAKKKDEAKIAKAEEELIK 180 Query: 180 AQTVFEDLNQELLEELPILYNSRIGCYVTIFQNISNLRDVFYREMSKLNHNLYEVMSKLE 239 AQ VFE++N +L EELP L+NSR+G YV FQ+I+ L + F++EMSKLN NL +V+ LE Sbjct: 181 AQKVFEEMNVDLQEELPSLWNSRVGFYVNTFQSIAGLEENFHKEMSKLNQNLNDVLVGLE 240 Query: 240 KQHSNKVFVVKGLSSSSRRSLVISPPVRTATVSSPLTSPTSPSTLSLKSESE 291 KQH + F VK S + +P + S P SP + + + E E Sbjct: 241 KQHGSNTFTVKAQPSDN------APAKGNKSPSPPDGSPAATPEIRVNHEPE 286 >gi|4757748 bridging integrator 1 isoform 8 [Homo sapiens] Length = 454 Score = 308 bits (788), Expect = 1e-83 Identities = 182/396 (45%), Positives = 235/396 (59%), Gaps = 35/396 (8%) Query: 1 MAE-GKAGGAAGLFAKQVQKKFSRAQEKVLQKLGKAVETKDERFEQSASNFYQQQAEGHK 59 MAE G G AG A VQKK +RAQEKVLQKLGKA ETKDE+FEQ NF +Q EG + Sbjct: 1 MAEMGSKGVTAGKIASNVQKKLTRAQEKVLQKLGKADETKDEQFEQCVQNFNKQLTEGTR 60 Query: 60 LYKDLKNFLSAVKVMHESSKRVSETLQEIYSSEWDGHEELKAIVWNNDLLWEDYEEKLAD 119 L KDL+ +L++VK MHE+SK+++E LQE+Y +W G +E I NNDLLW DY +KL D Sbjct: 61 LQKDLRTYLASVKAMHEASKKLNECLQEVYEPDWPGRDEANKIAENNDLLWMDYHQKLVD 120 Query: 120 QAVRTMEIYVAQFSEIKERIAKRGRKLVDYDSARHHLEAVQNAKKKDEAKTAKAEEEFNK 179 QA+ TM+ Y+ QF +IK RIAKRGRKLVDYDSARHH E++Q AKKKDEAK AKAEEE K Sbjct: 121 QALLTMDTYLGQFPDIKSRIAKRGRKLVDYDSARHHYESLQTAKKKDEAKIAKAEEELIK 180 Query: 180 AQTVFEDLNQELLEELPILYNSRIGCYVTIFQNISNLRDVFYREMSKLNHNLYEVMSKLE 239 AQ VFE++N +L EELP L+NSR+G YV FQ+I+ L + F++EMSKLN NL +V+ LE Sbjct: 181 AQKVFEEMNVDLQEELPSLWNSRVGFYVNTFQSIAGLEENFHKEMSKLNQNLNDVLVGLE 240 Query: 240 KQHSNKVFVVKGLSSSSRRSLVISPPVRTATVSSPLTSPTSPSTLSLKSESESVSATEDL 299 KQH + F VK + P S L K S++ A + Sbjct: 241 KQHGSNTFTVK---------------------AQPRKKSKLFSRLRRKKNSDNAPAKGNK 279 Query: 300 APDAAQGEDNSEIKELLEEEEIEKEGSEASSSEEDEPLPACNGPAQAQPSPTTERAKSQE 359 +P G + E + E A + LP + +QP+ +E A + Sbjct: 280 SPSPPDGSPAA-----TPEIRVNHEPEPAGGATPGATLP----KSPSQPAEASEVAGGTQ 330 Query: 360 EVLPSSTTPSPGGALSPSGQPSSSATEVVLRTRTAS 395 P++ P G + S SSS VV+ T A+ Sbjct: 331 ---PAAGAQEP-GETAASEAASSSLPAVVVETFPAT 362 >gi|4502081 amphiphysin isoform 1 [Homo sapiens] Length = 695 Score = 302 bits (774), Expect = 5e-82 Identities = 196/558 (35%), Positives = 297/558 (53%), Gaps = 30/558 (5%) Query: 11 GLFAKQVQKKFSRAQEKVLQKLGKAVETKDERFEQSASNFYQQQAEGHKLYKDLKNFLSA 70 G+FAK VQK+ +RAQEKVLQKLGKA ETKDE+FE+ NF +Q+AEG +L ++L+ +L+A Sbjct: 7 GIFAKNVQKRLNRAQEKVLQKLGKADETKDEQFEEYVQNFKRQEAEGTRLQRELRGYLAA 66 Query: 71 VKVMHESSKRVSETLQEIYSSEWDGHEELKAIVWNNDLLWEDYEEKLADQAVRTMEIYVA 130 +K M E+S +++E+L E+Y +W G E++K + D+LWED+ +KL D ++ T++ Y+ Sbjct: 67 IKGMQEASMKLTESLHEVYEPDWYGREDVKMVGEKCDVLWEDFHQKLVDGSLLTLDTYLG 126 Query: 131 QFSEIKERIAKRGRKLVDYDSARHHLEAVQNAKKKDEAKTAKAEEEFNKAQTVFEDLNQE 190 QF +IK RIAKR RKLVDYDSARHHLEA+Q++K+KDE++ +KAEEEF KAQ VFE+ N + Sbjct: 127 QFPDIKNRIAKRSRKLVDYDSARHHLEALQSSKRKDESRISKAEEEFQKAQKVFEEFNVD 186 Query: 191 LLEELPILYNSRIGCYVTIFQNISNLRDVFYREMSKLNHNLYEVMSKLEKQHSNKVFVVK 250 L EELP L++ R+G YV F+N+S+L F++E++ L H LYEVM+KL QH++K F ++ Sbjct: 187 LQEELPSLWSRRVGFYVNTFKNVSSLEAKFHKEIAVLCHKLYEVMTKLGDQHADKAFTIQ 246 Query: 251 GLSSSS---RRSLVISPPVRTATVSSPLTSPTSPSTLSLKSESESVSATEDLAPDAAQGE 307 G S S R + SPP SPL SPT+ +L S + A +G Sbjct: 247 GAPSDSGPLRIAKTPSPPEE----PSPLPSPTASPNHTLAPASPA-PARPRSPSQTRKGP 301 Query: 308 DNSEIKELLEEEEIEKEGSEASSSEEDEPLPACNGPAQAQ-PSPTTERAKSQEEVLPSST 366 + ++ +E+++E + + P + P+Q + P E + P Sbjct: 302 PVPPLPKVTPTKELQQENIISFFEDNFVPEISVTTPSQNEVPEVKKEETLLDLDFDPFKP 361 Query: 367 TPSPGGALSPSGQPSSSATEVVLRTRTASEGSEQPKKRASIQRTSAPPSRPPPPRATASP 426 +P G+ + P S L T S QP S + P + Sbjct: 362 EVTPAGSAGVTHSPMSQTLPWDL--WTTSTDLVQPASGGSFNGFTQPQD------TSLFT 413 Query: 427 RPSSGNIPSSPTASGGGSPTSPRASLGTGTASPRTSLEVSPN---PEPPEKPVRTPEAKE 483 + ++ + S PT P+A +P L++ + EP E+ V P A Sbjct: 414 MQTDQSMICNLAESEQAPPTEPKAEEPLAAVTPAVGLDLGMDTRAEEPVEEAVIIPGADA 473 Query: 484 NENIHN-QNPEELCTSPTLMTSQVASEPGEAKKMEDKEKDNKLISANSSEGQDQLQVSMV 542 + + + E + GE +E+ + I ++EG + Q Sbjct: 474 DAAVGTLVSAAEGAPGEEAEAEKATVPAGEGVSLEEAK-----IGTETTEGAESAQ---- 524 Query: 543 PENNNLTAPEPQEEVSTS 560 PE L A PQE+V S Sbjct: 525 PEAEELEATVPQEKVIPS 542 Score = 32.7 bits (73), Expect = 0.91 Identities = 54/251 (21%), Positives = 88/251 (35%), Gaps = 24/251 (9%) Query: 270 TVSSPLTSPTSPSTLSLKSESESVSATEDLAPDAAQGEDNSEIKELLEEEEIEKEGSEAS 329 T S+ L P S + + ++ + S D S I L E E+ + + Sbjct: 386 TTSTDLVQPASGGSFNGFTQPQDTSLF-------TMQTDQSMICNLAESEQ-----APPT 433 Query: 330 SSEEDEPLPACNGPAQAQPSPTTERAKSQEE--VLPSSTTPSPGGAL--SPSGQPSSSAT 385 + +EPL A T + EE ++P + + G L + G P A Sbjct: 434 EPKAEEPLAAVTPAVGLDLGMDTRAEEPVEEAVIIPGADADAAVGTLVSAAEGAPGEEA- 492 Query: 386 EVVLRTRTASEGSEQPKKRASIQRTSAPPSRPPPPRATASPRPSSGNIPSSPTASGGGSP 445 E T A EG + + + T S P + P IPS Sbjct: 493 EAEKATVPAGEGVSLEEAKIGTETTEGAESAQPEAEELEATVPQEKVIPSVVIEPASNHE 552 Query: 446 TSPRASLGTGTASPRTSLEVSPNPEPPEKPVRTPE-AKENENIHNQNPEELCTSPTLMTS 504 + G A P+ E + + PP TPE A E + I Q+P+ ++P + + Sbjct: 553 EEGENEITIG-AEPK---ETTEDAAPPGPTSETPELATEQKPI--QDPQPTPSAPAMGAA 606 Query: 505 QVASEPGEAKK 515 + EA + Sbjct: 607 DQLASAREASQ 617 >gi|21536404 bridging integrator 1 isoform 3 [Homo sapiens] Length = 506 Score = 301 bits (772), Expect = 8e-82 Identities = 191/431 (44%), Positives = 243/431 (56%), Gaps = 53/431 (12%) Query: 1 MAE-GKAGGAAGLFAKQVQKKFSRAQEKVLQKLGKAVETKDERFEQSASNFYQQQAEGHK 59 MAE G G AG A VQKK +RAQEKVLQKLGKA ETKDE+FEQ NF +Q EG + Sbjct: 1 MAEMGSKGVTAGKIASNVQKKLTRAQEKVLQKLGKADETKDEQFEQCVQNFNKQLTEGTR 60 Query: 60 LYKDLKNFLSAVKVMHESSKRVSETLQEIYSSEWDGHEELKAIVWNNDLLWEDYEEKLAD 119 L KDL+ +L++VK MHE+SK+++E LQE+Y +W G +E I NNDLLW DY +KL D Sbjct: 61 LQKDLRTYLASVKAMHEASKKLNECLQEVYEPDWPGRDEANKIAENNDLLWMDYHQKLVD 120 Query: 120 QAVRTMEIYVAQFSEIKERIAKRGRKLVDYDSARHHLEAVQNAKKKDEAKTAK------- 172 QA+ TM+ Y+ QF +IK RIAKRGRKLVDYDSARHH E++Q AKKKDEAK AK Sbjct: 121 QALLTMDTYLGQFPDIKSRIAKRGRKLVDYDSARHHYESLQTAKKKDEAKIAKPVSLLEK 180 Query: 173 ------------------------AEEEFNKAQTVFEDLNQELLEELPILYNSRIGCYVT 208 AEEE KAQ VFE++N +L EELP L+NSR+G YV Sbjct: 181 AAPQWCQGKLQAHLVAQTNLLRNQAEEELIKAQKVFEEMNVDLQEELPSLWNSRVGFYVN 240 Query: 209 IFQNISNLRDVFYREMSKLNHNLYEVMSKLEKQHSNKVFVVKGLSSSSRRSLVISPPVRT 268 FQ+I+ L + F++EMSKLN NL +V+ LEKQH + F VK S + +P Sbjct: 241 TFQSIAGLEENFHKEMSKLNQNLNDVLVGLEKQHGSNTFTVKAQPSDN------APAKGN 294 Query: 269 ATVSSPLTSPTSPSTLSLKSESESVSATEDLA--PDAAQGEDNSEIKELLEEEEIEKEGS 326 + S P SP + + + E E A P + S L E EG+ Sbjct: 295 KSPSPPDGSPAATPEIRVNHEPEPAGGATPGATLPKSPSQPTESPAGSLPSGEPSAAEGT 354 Query: 327 EASS--SEEDEPLPACNGPAQAQPSPTTERAKSQEEVLPSSTTPSPGGALSPSGQPSSSA 384 A S S+ EP P AQP+ +E A + P++ P G + S SSS Sbjct: 355 FAVSWPSQTAEPGP-------AQPAEASEVAGGTQ---PAAGAQEP-GETAASEAASSSL 403 Query: 385 TEVVLRTRTAS 395 VV+ T A+ Sbjct: 404 PAVVVETFPAT 414 Score = 30.0 bits (66), Expect = 5.9 Identities = 30/125 (24%), Positives = 40/125 (32%), Gaps = 18/125 (14%) Query: 400 QPKKRASIQRTSAP------PSRPPPPRATASPRPSSGNIPSSPTASGGGSPT-SPRASL 452 QP A + +P P+ P R P P+ G P + PT SP SL Sbjct: 284 QPSDNAPAKGNKSPSPPDGSPAATPEIRVNHEPEPAGGATPGATLPKSPSQPTESPAGSL 343 Query: 453 GTGTASPRTSLEVSPNPEPPEKPVRTPEAKENENIHNQNPEELCTSPTLMTSQVASEPGE 512 +G S P +P A+ +E P + A EPGE Sbjct: 344 PSGEPSAAEGTFAVSWPSQTAEPGPAQPAEASEVAGGTQP-----------AAGAQEPGE 392 Query: 513 AKKME 517 E Sbjct: 393 TAASE 397 >gi|21536423 amphiphysin isoform 2 [Homo sapiens] Length = 653 Score = 296 bits (759), Expect = 3e-80 Identities = 197/567 (34%), Positives = 294/567 (51%), Gaps = 43/567 (7%) Query: 11 GLFAKQVQKKFSRAQEKVLQKLGKAVETKDERFEQSASNFYQQQAEGHKLYKDLKNFLSA 70 G+FAK VQK+ +RAQEKVLQKLGKA ETKDE+FE+ NF +Q+AEG +L ++L+ +L+A Sbjct: 7 GIFAKNVQKRLNRAQEKVLQKLGKADETKDEQFEEYVQNFKRQEAEGTRLQRELRGYLAA 66 Query: 71 VKVMHESSKRVSETLQEIYSSEWDGHEELKAIVWNNDLLWEDYEEKLADQAVRTMEIYVA 130 +K M E+S +++E+L E+Y +W G E++K + D+LWED+ +KL D ++ T++ Y+ Sbjct: 67 IKGMQEASMKLTESLHEVYEPDWYGREDVKMVGEKCDVLWEDFHQKLVDGSLLTLDTYLG 126 Query: 131 QFSEIKERIAKRGRKLVDYDSARHHLEAVQNAKKKDEAKTAKAEEEFNKAQTVFEDLNQE 190 QF +IK RIAKR RKLVDYDSARHHLEA+Q++K+KDE++ +KAEEEF KAQ VFE+ N + Sbjct: 127 QFPDIKNRIAKRSRKLVDYDSARHHLEALQSSKRKDESRISKAEEEFQKAQKVFEEFNVD 186 Query: 191 LLEELPILYNSRIGCYVTIFQNISNLRDVFYREMSKLNHNLYEVMSKLEKQHSNKVFVVK 250 L EELP L++ R+G YV F+N+S+L F++E++ L H LYEVM+KL QH++K F ++ Sbjct: 187 LQEELPSLWSRRVGFYVNTFKNVSSLEAKFHKEIAVLCHKLYEVMTKLGDQHADKAFTIQ 246 Query: 251 GLSSSS---RRSLVISPPVRTATVSSPLTSPTSPSTLSLKSESESVSATEDLAPDAAQGE 307 G S S R + SPP SPL SPT+ +L S + A +G Sbjct: 247 GAPSDSGPLRIAKTPSPPEE----PSPLPSPTASPNHTLAPASPA-PARPRSPSQTRKGP 301 Query: 308 DNSEIKELLEEEEIEKEGSEASSSEEDEPLPACNGPAQAQ-PSPTTERAKSQEEVLPSST 366 + ++ +E+++E + + P + P+Q + P E + P Sbjct: 302 PVPPLPKVTPTKELQQENIISFFEDNFVPEISVTTPSQNEVPEVKKEETLLDLDFDPFKP 361 Query: 367 TPSPGGALSPSGQPSSSATEVVLRTRTASEGSEQPKKRASIQRTSAPPSRPPPPRATASP 426 +P G+ + P S L T S QP S + P T Sbjct: 362 EVTPAGSAGVTHSPMSQTLPWDL--WTTSTDLVQPASGGSFNGFTQPQDTSLFTMQTDQS 419 Query: 427 RPSSGNIPSSPTASGGGSPTSPRASLGTGTASPRTSLEVSPNPEPPEKPVRTPEAKENEN 486 + IP + + G+ S +P E P + V EAK Sbjct: 420 MICNLIIPGADADAAVGTLVS------AAEGAPGEEAEAEKATVPAGEGVSLEEAKIG-- 471 Query: 487 IHNQNPEELCTSPTLMTSQVASEPGEAKKMEDKEKDNKLI--------SANSSEGQDQLQ 538 T T S EA+++E K+I S + EG++++ Sbjct: 472 -------------TETTEGAESAQPEAEELEATVPQEKVIPSVVIEPASNHEEEGENEIT 518 Query: 539 VSMVPENNNLTAPEPQEEVSTSENPQL 565 + P+ A P TSE P+L Sbjct: 519 IGAEPKETTEDAAPPG---PTSETPEL 542 >gi|42542379 serine/arginine repetitive matrix 1 [Homo sapiens] Length = 904 Score = 71.2 bits (173), Expect = 2e-12 Identities = 88/340 (25%), Positives = 136/340 (40%), Gaps = 39/340 (11%) Query: 211 QNISNLRDVFY---REMSKLNHNLYEVMSKLEKQHSNKVFVVKGLSSSSRRSLVISPPVR 267 +NI+ + F +E K E ++ ++KQ +K K SSR S R Sbjct: 114 ENIAGIPSAFLELKKEEIKQRQIEQEKLASMKKQDEDKDKRDKEEKESSREKRERSRSPR 173 Query: 268 TATVSSPLTSPTSPSTLSLKSESESVSA---TEDLAPDAAQGEDNSEIKELLEEEEIEKE 324 SP S + S S S T+ +P A E + EL E KE Sbjct: 174 RRKSRSPSPRRRSSPVRRERKRSHSRSPRHRTKSRSPSPAP-EKKEKTPELPEPSVKVKE 232 Query: 325 GS--EASSSEE------DEPLPACNGPAQAQPSPTTERAKSQEEVLPSSTTPSPGGALSP 376 S EA+S+ + EP+P P + P +++ K +E+ P S + S + + Sbjct: 233 PSVQEATSTSDILKVPKPEPIPE---PKEPSPEKNSKKEKEKEKTRPRSRSRSKSRSRTR 289 Query: 377 SGQPSSSATEVVLRTRTASEGSEQ---PKKRASIQRTSAPPSRPPPPRATASPRPSSGNI 433 S PS + R+R+ S + P++R S +R + P PPPPR S P Sbjct: 290 SRSPSHTRPRRRHRSRSRSYSPRRRPSPRRRPSPRRRTPPRRMPPPPRHRRSRSPVRRRR 349 Query: 434 PSSPTASGGGSPTS-------PRASLGTGTASPRTSLEVSPNPEPPEK-----PVRTPEA 481 SS + SG S +S P+ ++ PR + +SP+ PP + P TP Sbjct: 350 RSSASLSGSSSSSSSSRSRSPPKKPPKRTSSPPRKTRRLSPSASPPRRRHRPSPPATPPP 409 Query: 482 KENENIHNQNPEELCTSPTLMTSQVASEPGEAKKMEDKEK 521 K H+ P++ S S+V+ PG K K Sbjct: 410 KTR---HSPTPQQ---SNRTRKSRVSVSPGRTSGKVTKHK 443 Score = 46.6 bits (109), Expect = 6e-05 Identities = 72/314 (22%), Positives = 107/314 (34%), Gaps = 38/314 (12%) Query: 253 SSSSRRSLVISPPVRTA---TVSSPLTSPTSPSTLSLKSESESVSATEDLAPDAAQGEDN 309 S+ +R+S V P RT+ T SPS + E + ED A + Sbjct: 420 SNRTRKSRVSVSPGRTSGKVTKHKGTEKRESPSPAPKPRKVELSESEEDKGGKMAAADSV 479 Query: 310 SEIKELLEEEEIEKEGSEASSSEEDEPLPACNGPAQAQPSPTTERAKSQEEVLPSSTTPS 369 + ++ + + S +SSS EDE P K+ E + S Sbjct: 480 QQRRQYRRQNQQSSSDSGSSSSSEDE-------------RPKRSHVKNGE--VGRRRRHS 524 Query: 370 PGGALSPSGQPSSSATEVVLRTRTASEGSEQPKKRASIQRTSAPPSRPPPPRATASPRPS 429 P + SPS P E R R S P +R PS PPPR +P P Sbjct: 525 PSRSASPS--PRKRQKETSPRGRRRRSPSPPPTRRRR------SPSPAPPPRRRRTPTP- 575 Query: 430 SGNIPSSPTASGGGSPTSPRASLGTGTASPRTSLEVSPNPEPPEKPVRTPEAKENENIHN 489 P SP R S SP SP+P PP++ +P Sbjct: 576 -------PPRRRTPSPPPRRRSPSPRRYSPPIQRRYSPSP-PPKRRTASPPPPPKRRASP 627 Query: 490 QNPEELCTSPTLMTSQVASEPGEAKKMEDKEKDNKLISANSSEGQDQLQVSMVPENNNLT 549 P + S + Q +S + + K K S + S + + S P + Sbjct: 628 SPPPKRRVSHSPPPKQRSSPVTKRRSPSLSSKHRKGSSPSRSTREAR---SPQPNKRHSP 684 Query: 550 APEPQEEVSTSENP 563 +P P+ ++S P Sbjct: 685 SPRPRAPQTSSSPP 698 Score = 45.4 bits (106), Expect = 1e-04 Identities = 66/307 (21%), Positives = 110/307 (35%), Gaps = 41/307 (13%) Query: 264 PPVRTATVSSPLTSPTSPSTLSLKSESESVSATEDLAPDAAQGEDNSEIKELLEEEEIEK 323 P RTA+ P SPS + S S + +P + + K + Sbjct: 610 PKRRTASPPPPPKRRASPSPPPKRRVSHSPPPKQRSSPVTKRRSPSLSSKH--------R 661 Query: 324 EGSEASSSEEDEPLPACNGPAQAQPSPTTERAKSQEEVLPSSTTPSPGGALSPSGQPSSS 383 +GS S S + P N P P + S + + SP SPS PS+ Sbjct: 662 KGSSPSRSTREARSPQPNKRHSPSPRPRAPQTSSSPPPVRRGASSSPQRRQSPS--PSTR 719 Query: 384 ATEVVLRTRTASEGSEQPKKRASIQRTSAPPSRPPPPRATASPRPSSGNIPSSPTASGGG 443 V RT +PKK I++ ++P P R +S R SG+ P A Sbjct: 720 PIRRVSRT-------PEPKK---IKKAASP--SPQSVRRVSSSRSVSGS--PEPAAKKPP 765 Query: 444 SPTSPRASLGTGTA-SPRTSLEVSPNPEPPEKPVRTPEAKENENIHNQNPEELCTSPTLM 502 +P SP S T SP ++ + +P P P R + + + ++ Sbjct: 766 APPSPVQSQSPSTNWSPAVPVKKAKSPTPSPSPPRNSDQEGGGKKKKKKKDK-------- 817 Query: 503 TSQVASEPGEAKKMEDKEKDNKLISANSSEGQDQLQV----SMVPENNNLTAPEPQEEVS 558 + + K K K K ++A ++ + + + + + APEP++E Sbjct: 818 ----KHKKDKKHKKHKKHKKEKAVAAAAAAAVTPAAIAAATTTLAQEEPVAAPEPKKETE 873 Query: 559 TSENPQL 565 + L Sbjct: 874 SEAEDNL 880 Score = 43.5 bits (101), Expect = 5e-04 Identities = 54/215 (25%), Positives = 82/215 (38%), Gaps = 38/215 (17%) Query: 348 PSPTTERAKSQEEVLP---SSTTPSPGGALSPSGQPSSSATEVVLRT--------RTASE 396 PSP +R + P +S +P P +S S P ++ V R R S Sbjct: 606 PSPPPKRRTASPPPPPKRRASPSPPPKRRVSHSPPPKQRSSPVTKRRSPSLSSKHRKGSS 665 Query: 397 GSEQPKKRASIQ--RTSAPPSRPPPPRATASPRPSSGNIPSSPTASGGGSPTS------- 447 S ++ S Q + +P RP P+ ++SP P SSP SP++ Sbjct: 666 PSRSTREARSPQPNKRHSPSPRPRAPQTSSSPPPVRRGASSSPQRRQSPSPSTRPIRRVS 725 Query: 448 ----PRASLGTGTASPR------TSLEVSPNPEPPEKPVRTPEAKENENIHNQN-----P 492 P+ + SP+ +S VS +PEP K P + + N P Sbjct: 726 RTPEPKKIKKAASPSPQSVRRVSSSRSVSGSPEPAAKKPPAPPSPVQSQSPSTNWSPAVP 785 Query: 493 EELCTSPTLMTSQVAS---EPGEAKKMEDKEKDNK 524 + SPT S + E G KK + K+K +K Sbjct: 786 VKKAKSPTPSPSPPRNSDQEGGGKKKKKKKDKKHK 820 Score = 42.0 bits (97), Expect = 0.001 Identities = 58/265 (21%), Positives = 89/265 (33%), Gaps = 34/265 (12%) Query: 264 PPVRTATVSSPLTSPTSPSTLSLKSESESVSATEDLAPDAAQGEDNSEIKELLEEEEIEK 323 PP R SP+ S+ SL S S S++ +P + S Sbjct: 334 PPPRHRRSRSPVRRRRR-SSASLSGSSSSSSSSRSRSPPKKPPKRTSSPPRKTRR----L 388 Query: 324 EGSEASSSEEDEPLPACNGPAQAQPSPTTERA----KSQEEVLPSST----TPSPGGALS 375 S + P P P + + SPT +++ KS+ V P T T G Sbjct: 389 SPSASPPRRRHRPSPPATPPPKTRHSPTPQQSNRTRKSRVSVSPGRTSGKVTKHKGTEKR 448 Query: 376 PSGQPSSSATEVVLRTRTASEGSEQP------KKRASIQRTSAPPSRPPPPRATASPRPS 429 S P+ +V L +G + ++R ++ S ++ RP Sbjct: 449 ESPSPAPKPRKVELSESEEDKGGKMAAADSVQQRRQYRRQNQQSSSDSGSSSSSEDERPK 508 Query: 430 SGNIPS---------SPTASGGGSP------TSPRASLGTGTASPRTSLEVSPNPEPPEK 474 ++ + SP+ S SP TSPR + P T SP+P PP + Sbjct: 509 RSHVKNGEVGRRRRHSPSRSASPSPRKRQKETSPRGRRRRSPSPPPTRRRRSPSPAPPPR 568 Query: 475 PVRTPEAKENENIHNQNPEELCTSP 499 RTP + P SP Sbjct: 569 RRRTPTPPPRRRTPSPPPRRRSPSP 593 >gi|157738649 neurofilament, medium polypeptide 150kDa isoform 1 [Homo sapiens] Length = 916 Score = 67.0 bits (162), Expect = 4e-11 Identities = 126/577 (21%), Positives = 213/577 (36%), Gaps = 78/577 (13%) Query: 41 ERFEQSASNFYQQQAEGHKLYKDLKNFLSAVKVMHESSKRVSETLQEIYSSEWDGHEELK 100 ERFE+ A +A L KD++ S VKV E K+V ++LQ+ + HEE Sbjct: 187 ERFEEEARLRDDTEAAIRALRKDIEE-ASLVKV--ELDKKV-QSLQDEVAFLRSNHEEEV 242 Query: 101 A-----------IVWNNDLLWEDYEEKLAD--------------QAVRTMEIYVAQFSEI 135 A V D L D L + QA + A+ +E Sbjct: 243 ADLLAQIQASHITVERKDYLKTDISTALKEIRSQLESHSDQNMHQAEEWFKCRYAKLTEA 302 Query: 136 ----KERIAKRGRKLVDY----DSARHHLEAVQNAKKKDEAKTAKAEEEFNKAQTVFEDL 187 KE I ++ +Y S LE+V+ K+ E + + EE N + ++D Sbjct: 303 AEQNKEAIRSAKEEIAEYRRQLQSKSIELESVRGTKESLERQLSDIEERHNHDLSSYQDT 362 Query: 188 NQELLEELPILYNSRIGCYVTIFQNISNLRDVFYREMSKLNHNLYEVMSKLEKQHSNKVF 247 Q+L EL + ++ +Q++ N++ E++ +++ E + S Sbjct: 363 IQQLENELRGT-KWEMARHLREYQDLLNVKMALDIEIAAYR----KLLEGEETRFSTFAG 417 Query: 248 VVKGLSSSSRRSLVISPPVRTATVSSP-----------LTSPTSPSTLSLKSESESVSAT 296 + G + R + IS ++ V +P + T + E + T Sbjct: 418 SITGPLYTHRPPITISSKIQKPKVEAPKLKVQHKFVEEIIEETKVEDEKSEMEEALTAIT 477 Query: 297 EDLAPDAAQGEDNSEIKELLEEEEIEKEGSEASSSEEDEPLPACNGPAQAQPSPTTERAK 356 E+LA + E KE EE+E E E E + + P+ A P + E + Sbjct: 478 EELAVSMKE-----EKKEAAEEKEEEPEAEEEEVAAKKSPVKA-TAPEVKEEEGEKEEEE 531 Query: 357 SQEEVL-----PSSTTPSPGGALSPSGQPSSSATEVVLRTRTASEGSE-QPKKRASIQRT 410 QEE S GG+ + T +EG E + K+ ++ Sbjct: 532 GQEEEEEEDEGAKSDQAEEGGSEKEGSSEKEEGEQEEGETEAEAEGEEAEAKEEKKVEEK 591 Query: 411 SAPPSRPPPPRATA---SPRPSSGNIPSSPTASGGGSPT--SPRASLGTGTASPRTSLEV 465 S + A A P + +P SP G SP SP G P++ +E Sbjct: 592 SEEVATKEELVADAKVEKPEKAKSPVPKSPVEEKGKSPVPKSPVEEKGKSPV-PKSPVEE 650 Query: 466 SPNPEPPEKPVRTPEAKENENIHNQNPEELCTSPT----LMTSQVASEPGEAKKMEDKEK 521 P+ PV E K + EE SP + ++ +E G+ ++ E++EK Sbjct: 651 KGKSPVPKSPV---EEKGKSPVSKSPVEEKAKSPVPKSPVEEAKSKAEVGKGEQKEEEEK 707 Query: 522 DNKLISANSSEGQDQLQVSMVPENNNLTAPEPQEEVS 558 + K + + + VPE +P +E V+ Sbjct: 708 EVKEAPKEEKVEKKEEKPKDVPEKKKAESPVKEEAVA 744 Score = 30.4 bits (67), Expect = 4.5 Identities = 35/145 (24%), Positives = 60/145 (41%), Gaps = 21/145 (14%) Query: 268 TATVSSPLTSPTSPSTLSLKSESESVSA------TEDLAPDAAQGEDNSEIK---ELLEE 318 T +V L T L+ E E A E+ + A+G +I E+ + Sbjct: 750 TKSVKVHLEKETKEEGKPLQQEKEKEKAGGEGGSEEEGSDKGAKGSRKEDIAVNGEVEGK 809 Query: 319 EEIEKEGSEASSSEEDEPLPACNGPAQAQPSPTTERA---KSQEEVLPSSTTPSPGGALS 375 EE+E+E E S E+E NG SP E+ KS+E+V+ + T Sbjct: 810 EEVEQETKEKGSGREEEKGVVTNG---LDLSPADEKKGGDKSEEKVVVTKTVE------K 860 Query: 376 PSGQPSSSATEVVLRTRTASEGSEQ 400 + + AT+ + ++ T ++ E+ Sbjct: 861 ITSEGGDGATKYITKSVTVTQKVEE 885 >gi|8923904 bridging integrator 3 [Homo sapiens] Length = 253 Score = 62.4 bits (150), Expect = 1e-09 Identities = 46/198 (23%), Positives = 88/198 (44%), Gaps = 7/198 (3%) Query: 37 ETKDERFEQSASNFYQQQAEGHKLYKDLKNFLSAVKVMHESSKRVSETLQEIYSSEWDGH 96 +T + FE+ Q + + +L KD+K A M +S+ ++S L E D Sbjct: 18 KTVERDFEREYGKLQQLEEQTRRLQKDMKKSTDADLAMSKSAVKISLDLLSNPLCEQDQD 77 Query: 97 -----EELKAIVWNNDLLWEDYEEKLADQAVRTMEIYVAQFSEIKERIAKRGRKLVDYDS 151 L + D ++ ++ + ++ + + F + + +R + L DY Sbjct: 78 LLNMVTALDTAMKRMDAFNQEKVNQIQKTVIEPLKKFGSVFPSLNMAVKRREQALQDYRR 137 Query: 152 ARHHLEAVQNAKKKDE--AKTAKAEEEFNKAQTVFEDLNQELLEELPILYNSRIGCYVTI 209 + +E + +K AK +A EE + FE N++LLEE+P Y SR+ + Sbjct: 138 LQAKVEKYEEKEKTGPVLAKLHQAREELRPVREDFEAKNRQLLEEMPRFYGSRLDYFQPS 197 Query: 210 FQNISNLRDVFYREMSKL 227 F+++ + V+Y EM K+ Sbjct: 198 FESLIRAQVVYYSEMHKI 215 >gi|55741677 SET domain containing 1A [Homo sapiens] Length = 1707 Score = 62.0 bits (149), Expect = 1e-09 Identities = 54/217 (24%), Positives = 83/217 (38%), Gaps = 20/217 (9%) Query: 283 TLSLKSESESVSATEDLAPDAAQGEDNSEIKELLEEEEIEKEGSEASSSEEDEPLPACNG 342 + +L SE E S D E++ E ++ E + K+ +E S E++E + Sbjct: 958 SFALDSEGEEASQESSSEKDEEDDEEDEEDEDREEAVDTTKKETEVSDGEDEESDSSSKC 1017 Query: 343 PAQAQPSPTTERAKSQEEVLPSSTTPSPGGALSPSGQPSSSATEVVLRTRTASEGSEQPK 402 A + E SS++ S + S S SSS ++SE E+ + Sbjct: 1018 SLYADSDGENDSTSDSESSSSSSSSSSSSSSSSSSSSSSSS--------ESSSEDEEEEE 1069 Query: 403 KRASIQRTSAPPSRPPPPRATASPRPSSGNIPSSPTASGGGSPTSPRASLGTGTASPRTS 462 + A++ S PP P P +P P +P GSP +P A P Sbjct: 1070 RPAALPSASPPPREVPVP----TPAPVEVPVPERV----AGSPVTPLPEQEASPARPAGP 1121 Query: 463 LEVSPNPEPPEKPVRTPEAKENENIHNQNPEELCTSP 499 E S PP P+R PE P+E +SP Sbjct: 1122 TEES----PPSAPLRPPEPPAGPPAPAPRPDERPSSP 1154 Score = 54.7 bits (130), Expect = 2e-07 Identities = 65/229 (28%), Positives = 86/229 (37%), Gaps = 51/229 (22%) Query: 254 SSSRRSLVISPPVRTATVSSPLTSPTSPSTLSLKSESESVSATEDLAPDAAQGEDNSEIK 313 SSS+ SL + S +S +S S+ S S S S S+ ++ E +SE Sbjct: 1013 SSSKCSLYADSDGENDSTSDSESSSSSSSSSSSSSSSSSSSS-------SSSSESSSE-- 1063 Query: 314 ELLEEEEIEKEGSEASSSEEDEPLPACNGPAQAQPSPTTERAKSQEEVLPSSTTPSPGGA 373 +EEE E+ + S+S +P P+P E V S TP P Sbjct: 1064 ---DEEEEERPAALPSASPPPREVPV--------PTPAPVEVPVPERVAGSPVTPLPEQE 1112 Query: 374 LSPSGQPSSSATEVVLRTRTASEGSEQPKKRASIQRTSAPPSRPPPPRATASPRPSSGNI 433 SP+ R A E P SAP P PP +P P Sbjct: 1113 ASPA--------------RPAGPTEESP--------PSAPLRPPEPPAGPPAPAPRPDER 1150 Query: 434 PSSPTASGGGSPTSPRASLGTGTASPRTSLEVSPNPEPPEKPVRTPEAK 482 PSSP P P T S +++EV P PEPP P P+AK Sbjct: 1151 PSSPI------PLLPPPKKRRKTVS-FSAIEVVPAPEPP--PATPPQAK 1190 Score = 37.0 bits (84), Expect = 0.048 Identities = 64/302 (21%), Positives = 105/302 (34%), Gaps = 31/302 (10%) Query: 265 PVRTATVSSPLT-SPTSPSTLSLKSESESVSATEDLAPDAAQGEDNSEIKELLEEEEIEK 323 P T V +P +P S T S ++ S+ P ++QG + ++ Sbjct: 228 PAGTTAVGTPGNGTPCSQDTSFSSSRQDTPSSFGQFTPQSSQGTPYTSRGSTPYSQDSAY 287 Query: 324 EGSEASSSEEDEPLPACNGPA------QAQPSPTTERAKSQEEVLPSSTTPSPGGALSPS 377 S S+S + A A + TT ++++ + +LS S Sbjct: 288 SSSTTSTSFKPRRSENSYQDAFSRRHFSASSASTTASTAIAATTAATASSSASSSSLSSS 347 Query: 378 GQPSSSATEVVLRTRTASEGSEQPKKRASIQRTSAPP---SRPPPPRA-----TASPRPS 429 SSS++ R+ A+ + + TS PP +R PP A TA P Sbjct: 348 SSSSSSSSSSQFRSSDANYPAYYESWNRYQRHTSYPPRRATREEPPGAPFAENTAERFPP 407 Query: 430 SGNI-----PSSPT-------ASGGGSPTSPRASLGTGTASP---RTSLEVSPNPEPPEK 474 S PS PT AS P P G G P R + SP P P + Sbjct: 408 SYTSYLPPEPSRPTDQDYRPPASEAPPPEPPEPGGGGGGGGPSPEREEVRTSPRPASPAR 467 Query: 475 PVRTPEAKENENIHNQNPEELCTS-PTLMTSQVASEPGEAKKMEDKEKDNKLISANSSEG 533 NE++ L + L+ Q + A E++E+++ ++ G Sbjct: 468 SGSPAPETTNESVPFAQHSSLDSRIEMLLKEQRSKFSFLASDTEEEEENSSMVLGARDTG 527 Query: 534 QD 535 + Sbjct: 528 SE 529 Score = 36.2 bits (82), Expect = 0.082 Identities = 54/222 (24%), Positives = 76/222 (34%), Gaps = 32/222 (14%) Query: 265 PVRTATVSSPLTSPTSPSTLSLKSESESVSATEDLAPDAAQGEDNSEIKELLEEEEIEKE 324 P R +SP P SP+ +S S + T + P A +S I+ LL+E+ K Sbjct: 451 PEREEVRTSP--RPASPA----RSGSPAPETTNESVPFAQHSSLDSRIEMLLKEQR-SKF 503 Query: 325 GSEASSSEEDEPLPACNGPAQAQPSPTTERAKSQEEVLPSST-----TPSPGGALSPSGQ 379 AS +EE+E + S A+ +PS + TP P A Sbjct: 504 SFLASDTEEEE-----------ENSSMVLGARDTGSEVPSGSGHGPCTPPPAPANFEDVA 552 Query: 380 PSSSATEVVLRTRTASEGSEQPKKRAS---------IQRTSAPPSRPPPPRATASPRPSS 430 P+ S R + G Q +S + S PP+ PP + P P Sbjct: 553 PTGSGEPGATRESPKANGQNQASPCSSGDDMEISDDDRGGSPPPAPTPPQQPPPPPPPPP 612 Query: 431 GNIPSSPTASGGGSPTSPRASLGTGTASPRTSLEVSPNPEPP 472 P + G P P L P P P PP Sbjct: 613 PPPPYLASLPLGYPPHQPAYLLPPRPDGPPPPEYPPPPPPPP 654 Score = 35.8 bits (81), Expect = 0.11 Identities = 57/251 (22%), Positives = 88/251 (35%), Gaps = 55/251 (21%) Query: 263 SPPVRTATVSSPLTSPTSPSTLSLKSESESVSATEDLAPDAAQGEDNSEIKELLEEEEIE 322 S P R AT P +P + +T +E S T L P+ ++ D ++ Sbjct: 381 SYPPRRATREEPPGAPFAENT----AERFPPSYTSYLPPEPSRPTD----------QDYR 426 Query: 323 KEGSEASSSEEDEPLPACNGPAQAQPSPTTERAKSQEEVLPSSTTPSPGGALS----PSG 378 SEA E EP G PSP E ++ + + SP + P Sbjct: 427 PPASEAPPPEPPEP---GGGGGGGGPSPEREEVRTSPRPASPARSGSPAPETTNESVPFA 483 Query: 379 QPSS--SATEVVLRTRT------ASEGSEQPKKRASI-----------QRTSAPPSRPPP 419 Q SS S E++L+ + AS+ E+ + + + + P PPP Sbjct: 484 QHSSLDSRIEMLLKEQRSKFSFLASDTEEEEENSSMVLGARDTGSEVPSGSGHGPCTPPP 543 Query: 420 ---------------PRATASPRPSSGNIPSSPTASGGGSPTSPRASLGTGTASPRTSLE 464 P AT ++G +SP +SG S G+ +P + Sbjct: 544 APANFEDVAPTGSGEPGATRESPKANGQNQASPCSSGDDMEISDDDRGGSPPPAPTPPQQ 603 Query: 465 VSPNPEPPEKP 475 P P PP P Sbjct: 604 PPPPPPPPPPP 614 Score = 33.9 bits (76), Expect = 0.41 Identities = 34/121 (28%), Positives = 51/121 (42%), Gaps = 17/121 (14%) Query: 353 ERAKSQEEVLPSS----TTPSPGGALSPSGQPSSSATEVV-LRTRTASEGSEQPKKRASI 407 +R K E ++ S T P+ G ALS Q S +ATE R R++S+ + P ++ Sbjct: 175 QRMKYYELIVNGSYTPQTVPTGGKALSEKFQGSGAATETAESRRRSSSDTAAYPAGTTAV 234 Query: 408 ----------QRTSAPPSRPPPPRATASPRPSSGNIPSSPTASGGGSPTSPRASLGTGTA 457 Q TS SR P + P S +P S G +P S ++ + T Sbjct: 235 GTPGNGTPCSQDTSFSSSRQDTPSSFGQFTPQSSQ--GTPYTSRGSTPYSQDSAYSSSTT 292 Query: 458 S 458 S Sbjct: 293 S 293 Score = 33.1 bits (74), Expect = 0.70 Identities = 28/103 (27%), Positives = 39/103 (37%), Gaps = 13/103 (12%) Query: 335 EPLPACNGPAQAQPSPTTERAKSQEEVLPSSTTPSPGGALSP------SGQPSSSATEVV 388 EP+PA PA SP E ++ E V+ + P P G+ E Sbjct: 1319 EPVPA---PAALFSSPADEVLEAPEVVVAEAEEPKPQQLQQQREEGEEEGEEEGEEEEEE 1375 Query: 389 LRTRTASEGSEQPKKRASIQ----RTSAPPSRPPPPRATASPR 427 ++S E +R S++ R PP PPPP PR Sbjct: 1376 SSDSSSSSDGEGALRRRSLRSHARRRRPPPPPPPPPPRAYEPR 1418 Score = 30.0 bits (66), Expect = 5.9 Identities = 23/78 (29%), Positives = 38/78 (48%), Gaps = 5/78 (6%) Query: 263 SPPVRTATVSSPLTSP----TSPSTLSLKSESESVSATEDLAPDAAQGEDNSEIKELLEE 318 +PP P+ +P +SP+ L++ V+ E+ P Q + +E EE Sbjct: 1309 TPPAPALRPPEPVPAPAALFSSPADEVLEAPEVVVAEAEEPKPQQLQQQREEGEEEGEEE 1368 Query: 319 -EEIEKEGSEASSSEEDE 335 EE E+E S++SSS + E Sbjct: 1369 GEEEEEESSDSSSSSDGE 1386 >gi|189181720 proteoglycan 4 isoform B [Homo sapiens] Length = 1363 Score = 61.6 bits (148), Expect = 2e-09 Identities = 92/438 (21%), Positives = 154/438 (35%), Gaps = 53/438 (12%) Query: 162 AKKKDEAKTAKAEEEFNKAQTVFEDLNQELLEELPILYNSRIGCYVTIFQNISNLRDVFY 221 A + ++ T ++ + NK +T ++E+ EE + N + + S +R + Sbjct: 84 ASQTIKSTTKRSPKPPNKKKTKKVIESEEITEEHSVSENQESSSSSSSSSSSSTIRKIKS 143 Query: 222 REMSKLNHNLYEVM-------SKLEKQHSNKVFVV----KGL------------SSSSRR 258 + S N L + + ++ +K+ + K VV GL S++ Sbjct: 144 SKNSAANRELQKKLKVKDNKKNRTKKKPTPKPPVVDEAGSGLDNGDFKVTTPDTSTTQHN 203 Query: 259 SLVISPPVRTATV-----SSPLTSPTSPSTLSLKSESESVSATEDLAPDAAQGEDNSE-I 312 + SP + TA S P S TS T ++ +V E + D E Sbjct: 204 KVSTSPKITTAKPINPRPSLPPNSDTSKETSLTVNKETTVETKETTTTNKQTSTDGKEKT 263 Query: 313 KELLEEEEIEKEGSE---ASSSEEDEPLPACN----GPAQA---QPSPTTERAKSQEEVL 362 E + IEK ++ +S +P P GPA +P+PTT + Sbjct: 264 TSAKETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKE------- 316 Query: 363 PSSTTPSPGGALSPSGQPSSSATEVVLRTRTASEGSEQPKKRASIQRTSAPPSRPPPPRA 422 P+STTP + P++ T++A PK+ A P+ P P Sbjct: 317 PASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPT---TPKEPAPTTTKEPAPTTPKEPAP 373 Query: 423 TASPRPSSGNIPSSPTASGGGSPTSPRASLGTGTASPRTSLEVSPNPEPPEKPVRTPEAK 482 T + P+ S+PT +PT+P+ T P + P P P++P P K Sbjct: 374 TTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEP--APTTK 431 Query: 483 ENENIHNQNPEELCTSPTLMTSQVASEPGEAKKMEDKEKDNKLISANSSEGQDQLQVSMV 542 E + P T+P EP E K S + + Sbjct: 432 EPAPTTPKEPAP--TAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSA 489 Query: 543 PENNNLTAPEPQEEVSTS 560 P AP + T+ Sbjct: 490 PTTTKEPAPTTTKSAPTT 507 Score = 59.3 bits (142), Expect = 9e-09 Identities = 52/226 (23%), Positives = 87/226 (38%), Gaps = 15/226 (6%) Query: 265 PVRTATVSSPLTSPTSPSTLSLKSESESV------SATEDLAPDAAQGEDNS--EIKELL 316 P T T S+P T+P P+ + K + + + T++ AP + + E Sbjct: 340 PAPTTTKSAP-TTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTT 398 Query: 317 EEEEIEKEGSEASSSEEDEPLPACNGPAQAQPSPTTERAKSQEEVLPSSTTPSPGGALSP 376 ++ E + + EP P +P+PTT+ P+ T P +P Sbjct: 399 PKKPAPTTPKEPAPTTPKEPTPT----TPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTP 454 Query: 377 SGQPSSSATEVVLRTRTASEGSEQPKKRASIQRTSAPPSRPPPPRATASPRPSSGNIPSS 436 +P+ + + T T PK+ A SAP + P T P++ PS Sbjct: 455 K-EPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPS- 512 Query: 437 PTASGGGSPTSPRASLGTGTASPRTSLEVSPNPEPPEKPVRTPEAK 482 PT + +PT+P+ T P + P P P++P T K Sbjct: 513 PTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKK 558 Score = 56.6 bits (135), Expect = 6e-08 Identities = 46/217 (21%), Positives = 75/217 (34%), Gaps = 4/217 (1%) Query: 265 PVRTATVSSPLTSPTSPSTLSLKSESESVSATEDLAPDAAQGEDNSEIKELLEEEEIEKE 324 P T T T+P P+ + K + + + + P + +E Sbjct: 355 PAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTT 414 Query: 325 GSEASSSEEDEPLPACNGPAQAQPS-PTTERAKSQEEVLPSSTTPSPGGALSPSGQPSSS 383 E + + EP P PA P P K P P+ +P+ S Sbjct: 415 PKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPS 474 Query: 384 ATEVVLRTRTASEGSEQPKKRASIQRTSAPPSRP--PPPRATASPRPSSGNIPSSPTASG 441 T T ++ + K + T + P+ P P P T P P++ P +PT Sbjct: 475 PTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEP-APTTPK 533 Query: 442 GGSPTSPRASLGTGTASPRTSLEVSPNPEPPEKPVRT 478 +PT+P+ T P + P P P++P T Sbjct: 534 KPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPT 570 Score = 50.8 bits (120), Expect = 3e-06 Identities = 59/289 (20%), Positives = 99/289 (34%), Gaps = 19/289 (6%) Query: 250 KGLSSSSRRSLVISPPVRTATVSSPLTSPTSPSTLSLKSESESVSATEDLAPDAA----- 304 K S + + + T T T +T + +++S ++ +DLAP + Sbjct: 231 KETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAKP 290 Query: 305 --QGEDNSEIKELLEEEE-IEKEGSEASSSEEDEPLPACNGPAQA---QPSPTTERAKSQ 358 + E ++ L +E E +S+ EP P A +P+PTT ++ Sbjct: 291 TPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPT 350 Query: 359 EEVLPSSTTPSPGGALSPSGQPSSSATEVVLRTRTASEGSEQ-------PKKRASIQRTS 411 P+ TT +P +P+ + T+ T T S + PKK A Sbjct: 351 TPKEPAPTTTKEPAPTTPK-EPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKE 409 Query: 412 APPSRPPPPRATASPRPSSGNIPSSPTASGGGSPTSPRASLGTGTASPRTSLEVSPNPEP 471 P+ P P T P+ +PT +PT+P+ T P + P P Sbjct: 410 PAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTT 469 Query: 472 PEKPVRTPEAKENENIHNQNPEELCTSPTLMTSQVASEPGEAKKMEDKE 520 ++P T + P T + P E KE Sbjct: 470 TKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKE 518 Score = 50.1 bits (118), Expect = 6e-06 Identities = 56/222 (25%), Positives = 91/222 (40%), Gaps = 26/222 (11%) Query: 265 PVRTATVSSPLTS----PTSPSTLSLKSESESVSATEDLAPDAAQGEDNSEIKE---LLE 317 P T T S+P T+ PT+ + + S + T++ AP + + K+ Sbjct: 481 PAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTP 540 Query: 318 EEEIEKEGSEASSSEEDEPLPACNGPAQAQPSPTTERAKSQEEVLPSSTTPSPGGALSPS 377 +E E + + +P P +P+PTT K P TP+ L+P+ Sbjct: 541 KEPAPTTPKEPAPTTTKKPAPT----TPKEPAPTTP--KETAPTTPKKLTPTTPEKLAPT 594 Query: 378 G--QPSSSATEVVLRTRTASEGSEQPKKRASIQRTSAPPSRP--PPPRATASPRPSSGNI 433 +P+ + E + T P++ A +A P+ P P P P P++ Sbjct: 595 TPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKE 654 Query: 434 PSSPTASGGGSPTSPRASLGTGTASPRTSLEVSPNPEPPEKP 475 P+ PT +PT+P+ GTA P T E P P P+KP Sbjct: 655 PA-PTTPKETAPTTPK-----GTA-PTTLKE--PAPTTPKKP 687 Score = 50.1 bits (118), Expect = 6e-06 Identities = 68/283 (24%), Positives = 102/283 (36%), Gaps = 43/283 (15%) Query: 264 PPVRTATVSSPLT----SPTSPSTLSLKSESESVSAT-EDLAPDAAQGEDNSEIKELLEE 318 P T ++P T +PT+P + + E T ++ AP +G + +KE Sbjct: 623 PAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPT 682 Query: 319 EEIEKEGSEASSSEEDEPLPA-CNGPAQAQPSPTTERAKSQEEVLPSSTTPSPGGALSPS 377 + E + + EP C+ PA P T + P+ TTP +P Sbjct: 683 TPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKE----PAPTTPKEPAPTTPK 738 Query: 378 GQ------------PSSSATEVVLRTRTASEGSEQPKKRASIQRTSAPPSRP--PPPRAT 423 G P A + + T T S K A P+ P P P Sbjct: 739 GTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTP 798 Query: 424 ASPRPSSGNIPSSPTASGGGSPTSPRASLGTGTASPRTSLEVSPNPEPPEKPVR-TPEAK 482 P P++ P PT S +PT T T++ SP+ PE TP+A Sbjct: 799 KKPAPTTPETPP-PTTSEVSTPT---------TTKEPTTIHKSPDESTPELSAEPTPKAL 848 Query: 483 ENENIHNQNPEELCTSPTLMTSQVASEPGEAKKMEDKEKDNKL 525 EN +P+E PT T A++P +DK + L Sbjct: 849 EN------SPKEPGV-PTTKT-PAATKPEMTTTAKDKTTERDL 883 Score = 47.8 bits (112), Expect = 3e-05 Identities = 49/223 (21%), Positives = 80/223 (35%), Gaps = 38/223 (17%) Query: 265 PVRTATVSSPLTSPTSPSTLSLKSESESVSATEDLAPDAAQGEDNSEIKELLEEEEIEKE 324 P T T T+P P+ + KS + + T++ AP + + Sbjct: 465 PAPTTTKEPSPTTPKEPAPTTTKS---APTTTKEPAPTTTKSAPTTP------------- 508 Query: 325 GSEASSSEEDEPLPACNGPAQAQPSPTTERAKSQEEVLPSSTTPSPGGALSPSGQPSSSA 384 E S + EP P +P+PTT + P+ TTP +P +P+ + Sbjct: 509 -KEPSPTTTKEPAPT----TPKEPAPTTPKK-------PAPTTPKEPAPTTPK-EPAPTT 555 Query: 385 TEVVLRTRTASEGSEQPKKRASIQRTSAPPSRP-------PPPRATASPRPSSGNIPSSP 437 T+ T PK+ A P+ P P A +P + P P Sbjct: 556 TKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEP 615 Query: 438 TASGGG--SPTSPRASLGTGTASPRTSLEVSPNPEPPEKPVRT 478 T + +PT+P+A+ P + P P P++P T Sbjct: 616 TPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPT 658 Score = 43.9 bits (102), Expect = 4e-04 Identities = 69/304 (22%), Positives = 107/304 (35%), Gaps = 21/304 (6%) Query: 265 PVRTATVSSPLTSPTSPSTLSLKSESESVSATEDLAPDAAQGEDNSEIKELLEEEEIEKE 324 P T T S+P T+P PS + K + + ++ AP + + KE E Sbjct: 496 PAPTTTKSAP-TTPKEPSPTTTKEPAPTTP--KEPAPTTPKKPAPTTPKEPAPTTPKEPA 552 Query: 325 GSEASSSEEDEPL-PACNGPAQAQPS------PTT-ERAKSQEEVLPSSTTPSPGGALSP 376 + P PA P + P+ PTT E+ P+ TTP +P Sbjct: 553 PTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTP 612 Query: 377 SGQPSSSATEVVLRTRTASEGSEQPKKRASIQRTSAPPSRPPPPRATASPRPSSGNIP-- 434 +P+ + E T + PK+ A P+ P P A +P+ ++ P Sbjct: 613 E-EPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEP-APTTPKETAPTTPKG 670 Query: 435 SSPTASGGGSPTSPRAS-----LGTGTASPRTSLEVSPNPEPPEKPVRTPEAKENENIHN 489 ++PT +PT+P+ T T P ++ P P P+ T KE Sbjct: 671 TAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPT-TPKEPAPTTP 729 Query: 490 QNPEELCTSPTLMTSQVASEPGEAKKMEDKEKDNKLISANSSEGQDQLQVSMVPENNNLT 549 + P T T+ P KK KE +S D+ + E T Sbjct: 730 KEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTT 789 Query: 550 APEP 553 EP Sbjct: 790 PKEP 793 Score = 43.1 bits (100), Expect = 7e-04 Identities = 56/275 (20%), Positives = 96/275 (34%), Gaps = 23/275 (8%) Query: 263 SPPVRTATVSSPLTSPTSPSTLSLKSESESVSATEDLAPDAAQGEDNSEIKELLEEEEIE 322 +PP T+ VS+P T+ P+T+ + + + + P A + + Sbjct: 808 TPPPTTSEVSTPTTTK-EPTTIHKSPDESTPELSAEPTPKALENSPKEPGVPTTKTPAAT 866 Query: 323 KEGSEASSSEE--DEPLPACNGPAQAQPSPTTERAKSQEEVLPSSTTPSPGGALSPSGQP 380 K ++ ++ + L A P T E A + E+ S T + S + Q Sbjct: 867 KPEMTTTAKDKTTERDLRTTPETTTAAPKMTKETATTTEKTTESKITATTTQVTSTTTQD 926 Query: 381 SSSATEVVLRTRTASEGSEQPKKRASIQRTSAPPSRPPPPRATASPRPSSGNIPSSPTAS 440 ++ L+T T + KK + P P+ A+ ++ P PT Sbjct: 927 TTPFKITTLKTTTLAPKVTTTKKTITTTEIMNKPEETAKPKDRATNSKATTPKPQKPTK- 985 Query: 441 GGGSPTSPRASLGTGTASPRTSLEVSPNPEPPEKPVRTP-EAKENENIHNQNPEELCTSP 499 +P P T T P+T V KP TP K + NP Sbjct: 986 ---APKKP-----TSTKKPKTMPRV-------RKPKTTPTPRKMTSTMPELNPTSRIAEA 1030 Query: 500 TLMTSQVASEPGEAKKMEDKEKDNKLISANSSEGQ 534 L T+ ++ +K +E K A +EG+ Sbjct: 1031 MLQTTTRPNQTPNSKLVEVNPKSE---DAGGAEGE 1062 Score = 38.9 bits (89), Expect = 0.013 Identities = 60/300 (20%), Positives = 107/300 (35%), Gaps = 74/300 (24%) Query: 269 ATVSSPLTSPTSPSTLSLKSESESVSATEDLAPDAAQGEDNSEIKELLEEEEIEKEGSEA 328 A V +P + P+S S+++ +T +P + + + K+++E EEI +E S + Sbjct: 64 AEVHNPTSPPSSKKAPPPSGASQTIKSTTKRSP---KPPNKKKTKKVIESEEITEEHSVS 120 Query: 329 SSSEEDEPLPACNGPAQAQPSPTTERAKSQEEVLPSSTTPSPGGALSPSGQPSSSATEVV 388 + E S S SSS+T Sbjct: 121 ENQESS----------------------------------------SSSSSSSSSSTIRK 140 Query: 389 LRTRTASEGSEQPKKRASIQ-----RTSAPPSRPPPPRATASPRPSSGNI----PSSPTA 439 +++ S + + +K+ ++ RT P+ PP A +G+ P + T Sbjct: 141 IKSSKNSAANRELQKKLKVKDNKKNRTKKKPTPKPPVVDEAGSGLDNGDFKVTTPDTSTT 200 Query: 440 SGGGSPTSPRASLGTGTASPRTSLEVSPNPEPPEKPVRTPEAKENENIHNQNPEELCTSP 499 TSP+ + TA P NP P P + + ++ + E T Sbjct: 201 QHNKVSTSPKIT----TAKP-------INPRPSLPPNSDTSKETSLTVNKETTVE--TKE 247 Query: 500 TLMTSQVASEPGEAKKMEDKEKDNKLISANSSEGQDQLQVSMVPENNNLTAPEPQEEVST 559 T T++ S G+ K KE S + +D + P + L P P+ E +T Sbjct: 248 TTTTNKQTSTDGKEKTTSAKETQ----SIEKTSAKD-----LAPTSKVLAKPTPKAETTT 298 >gi|67190163 proteoglycan 4 isoform A [Homo sapiens] Length = 1404 Score = 61.6 bits (148), Expect = 2e-09 Identities = 92/438 (21%), Positives = 154/438 (35%), Gaps = 53/438 (12%) Query: 162 AKKKDEAKTAKAEEEFNKAQTVFEDLNQELLEELPILYNSRIGCYVTIFQNISNLRDVFY 221 A + ++ T ++ + NK +T ++E+ EE + N + + S +R + Sbjct: 125 ASQTIKSTTKRSPKPPNKKKTKKVIESEEITEEHSVSENQESSSSSSSSSSSSTIRKIKS 184 Query: 222 REMSKLNHNLYEVM-------SKLEKQHSNKVFVV----KGL------------SSSSRR 258 + S N L + + ++ +K+ + K VV GL S++ Sbjct: 185 SKNSAANRELQKKLKVKDNKKNRTKKKPTPKPPVVDEAGSGLDNGDFKVTTPDTSTTQHN 244 Query: 259 SLVISPPVRTATV-----SSPLTSPTSPSTLSLKSESESVSATEDLAPDAAQGEDNSE-I 312 + SP + TA S P S TS T ++ +V E + D E Sbjct: 245 KVSTSPKITTAKPINPRPSLPPNSDTSKETSLTVNKETTVETKETTTTNKQTSTDGKEKT 304 Query: 313 KELLEEEEIEKEGSE---ASSSEEDEPLPACN----GPAQA---QPSPTTERAKSQEEVL 362 E + IEK ++ +S +P P GPA +P+PTT + Sbjct: 305 TSAKETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKE------- 357 Query: 363 PSSTTPSPGGALSPSGQPSSSATEVVLRTRTASEGSEQPKKRASIQRTSAPPSRPPPPRA 422 P+STTP + P++ T++A PK+ A P+ P P Sbjct: 358 PASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPT---TPKEPAPTTTKEPAPTTPKEPAP 414 Query: 423 TASPRPSSGNIPSSPTASGGGSPTSPRASLGTGTASPRTSLEVSPNPEPPEKPVRTPEAK 482 T + P+ S+PT +PT+P+ T P + P P P++P P K Sbjct: 415 TTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEP--APTTK 472 Query: 483 ENENIHNQNPEELCTSPTLMTSQVASEPGEAKKMEDKEKDNKLISANSSEGQDQLQVSMV 542 E + P T+P EP E K S + + Sbjct: 473 EPAPTTPKEPAP--TAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSA 530 Query: 543 PENNNLTAPEPQEEVSTS 560 P AP + T+ Sbjct: 531 PTTTKEPAPTTTKSAPTT 548 Score = 59.3 bits (142), Expect = 9e-09 Identities = 52/226 (23%), Positives = 87/226 (38%), Gaps = 15/226 (6%) Query: 265 PVRTATVSSPLTSPTSPSTLSLKSESESV------SATEDLAPDAAQGEDNS--EIKELL 316 P T T S+P T+P P+ + K + + + T++ AP + + E Sbjct: 381 PAPTTTKSAP-TTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTT 439 Query: 317 EEEEIEKEGSEASSSEEDEPLPACNGPAQAQPSPTTERAKSQEEVLPSSTTPSPGGALSP 376 ++ E + + EP P +P+PTT+ P+ T P +P Sbjct: 440 PKKPAPTTPKEPAPTTPKEPTPT----TPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTP 495 Query: 377 SGQPSSSATEVVLRTRTASEGSEQPKKRASIQRTSAPPSRPPPPRATASPRPSSGNIPSS 436 +P+ + + T T PK+ A SAP + P T P++ PS Sbjct: 496 K-EPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPS- 553 Query: 437 PTASGGGSPTSPRASLGTGTASPRTSLEVSPNPEPPEKPVRTPEAK 482 PT + +PT+P+ T P + P P P++P T K Sbjct: 554 PTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKK 599 Score = 56.6 bits (135), Expect = 6e-08 Identities = 46/217 (21%), Positives = 75/217 (34%), Gaps = 4/217 (1%) Query: 265 PVRTATVSSPLTSPTSPSTLSLKSESESVSATEDLAPDAAQGEDNSEIKELLEEEEIEKE 324 P T T T+P P+ + K + + + + P + +E Sbjct: 396 PAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTT 455 Query: 325 GSEASSSEEDEPLPACNGPAQAQPS-PTTERAKSQEEVLPSSTTPSPGGALSPSGQPSSS 383 E + + EP P PA P P K P P+ +P+ S Sbjct: 456 PKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPS 515 Query: 384 ATEVVLRTRTASEGSEQPKKRASIQRTSAPPSRP--PPPRATASPRPSSGNIPSSPTASG 441 T T ++ + K + T + P+ P P P T P P++ P +PT Sbjct: 516 PTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEP-APTTPK 574 Query: 442 GGSPTSPRASLGTGTASPRTSLEVSPNPEPPEKPVRT 478 +PT+P+ T P + P P P++P T Sbjct: 575 KPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPT 611 Score = 50.8 bits (120), Expect = 3e-06 Identities = 59/289 (20%), Positives = 99/289 (34%), Gaps = 19/289 (6%) Query: 250 KGLSSSSRRSLVISPPVRTATVSSPLTSPTSPSTLSLKSESESVSATEDLAPDAA----- 304 K S + + + T T T +T + +++S ++ +DLAP + Sbjct: 272 KETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAKP 331 Query: 305 --QGEDNSEIKELLEEEE-IEKEGSEASSSEEDEPLPACNGPAQA---QPSPTTERAKSQ 358 + E ++ L +E E +S+ EP P A +P+PTT ++ Sbjct: 332 TPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPT 391 Query: 359 EEVLPSSTTPSPGGALSPSGQPSSSATEVVLRTRTASEGSEQ-------PKKRASIQRTS 411 P+ TT +P +P+ + T+ T T S + PKK A Sbjct: 392 TPKEPAPTTTKEPAPTTPK-EPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKE 450 Query: 412 APPSRPPPPRATASPRPSSGNIPSSPTASGGGSPTSPRASLGTGTASPRTSLEVSPNPEP 471 P+ P P T P+ +PT +PT+P+ T P + P P Sbjct: 451 PAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTT 510 Query: 472 PEKPVRTPEAKENENIHNQNPEELCTSPTLMTSQVASEPGEAKKMEDKE 520 ++P T + P T + P E KE Sbjct: 511 TKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKE 559 Score = 50.1 bits (118), Expect = 6e-06 Identities = 56/222 (25%), Positives = 91/222 (40%), Gaps = 26/222 (11%) Query: 265 PVRTATVSSPLTS----PTSPSTLSLKSESESVSATEDLAPDAAQGEDNSEIKE---LLE 317 P T T S+P T+ PT+ + + S + T++ AP + + K+ Sbjct: 522 PAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTP 581 Query: 318 EEEIEKEGSEASSSEEDEPLPACNGPAQAQPSPTTERAKSQEEVLPSSTTPSPGGALSPS 377 +E E + + +P P +P+PTT K P TP+ L+P+ Sbjct: 582 KEPAPTTPKEPAPTTTKKPAPT----TPKEPAPTTP--KETAPTTPKKLTPTTPEKLAPT 635 Query: 378 G--QPSSSATEVVLRTRTASEGSEQPKKRASIQRTSAPPSRP--PPPRATASPRPSSGNI 433 +P+ + E + T P++ A +A P+ P P P P P++ Sbjct: 636 TPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKE 695 Query: 434 PSSPTASGGGSPTSPRASLGTGTASPRTSLEVSPNPEPPEKP 475 P+ PT +PT+P+ GTA P T E P P P+KP Sbjct: 696 PA-PTTPKETAPTTPK-----GTA-PTTLKE--PAPTTPKKP 728 Score = 50.1 bits (118), Expect = 6e-06 Identities = 68/283 (24%), Positives = 102/283 (36%), Gaps = 43/283 (15%) Query: 264 PPVRTATVSSPLT----SPTSPSTLSLKSESESVSAT-EDLAPDAAQGEDNSEIKELLEE 318 P T ++P T +PT+P + + E T ++ AP +G + +KE Sbjct: 664 PAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPT 723 Query: 319 EEIEKEGSEASSSEEDEPLPA-CNGPAQAQPSPTTERAKSQEEVLPSSTTPSPGGALSPS 377 + E + + EP C+ PA P T + P+ TTP +P Sbjct: 724 TPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKE----PAPTTPKEPAPTTPK 779 Query: 378 GQ------------PSSSATEVVLRTRTASEGSEQPKKRASIQRTSAPPSRP--PPPRAT 423 G P A + + T T S K A P+ P P P Sbjct: 780 GTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTP 839 Query: 424 ASPRPSSGNIPSSPTASGGGSPTSPRASLGTGTASPRTSLEVSPNPEPPEKPVR-TPEAK 482 P P++ P PT S +PT T T++ SP+ PE TP+A Sbjct: 840 KKPAPTTPETPP-PTTSEVSTPT---------TTKEPTTIHKSPDESTPELSAEPTPKAL 889 Query: 483 ENENIHNQNPEELCTSPTLMTSQVASEPGEAKKMEDKEKDNKL 525 EN +P+E PT T A++P +DK + L Sbjct: 890 EN------SPKEPGV-PTTKT-PAATKPEMTTTAKDKTTERDL 924 Score = 47.8 bits (112), Expect = 3e-05 Identities = 49/223 (21%), Positives = 80/223 (35%), Gaps = 38/223 (17%) Query: 265 PVRTATVSSPLTSPTSPSTLSLKSESESVSATEDLAPDAAQGEDNSEIKELLEEEEIEKE 324 P T T T+P P+ + KS + + T++ AP + + Sbjct: 506 PAPTTTKEPSPTTPKEPAPTTTKS---APTTTKEPAPTTTKSAPTTP------------- 549 Query: 325 GSEASSSEEDEPLPACNGPAQAQPSPTTERAKSQEEVLPSSTTPSPGGALSPSGQPSSSA 384 E S + EP P +P+PTT + P+ TTP +P +P+ + Sbjct: 550 -KEPSPTTTKEPAPT----TPKEPAPTTPKK-------PAPTTPKEPAPTTPK-EPAPTT 596 Query: 385 TEVVLRTRTASEGSEQPKKRASIQRTSAPPSRP-------PPPRATASPRPSSGNIPSSP 437 T+ T PK+ A P+ P P A +P + P P Sbjct: 597 TKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEP 656 Query: 438 TASGGG--SPTSPRASLGTGTASPRTSLEVSPNPEPPEKPVRT 478 T + +PT+P+A+ P + P P P++P T Sbjct: 657 TPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPT 699 Score = 43.9 bits (102), Expect = 4e-04 Identities = 69/304 (22%), Positives = 107/304 (35%), Gaps = 21/304 (6%) Query: 265 PVRTATVSSPLTSPTSPSTLSLKSESESVSATEDLAPDAAQGEDNSEIKELLEEEEIEKE 324 P T T S+P T+P PS + K + + ++ AP + + KE E Sbjct: 537 PAPTTTKSAP-TTPKEPSPTTTKEPAPTTP--KEPAPTTPKKPAPTTPKEPAPTTPKEPA 593 Query: 325 GSEASSSEEDEPL-PACNGPAQAQPS------PTT-ERAKSQEEVLPSSTTPSPGGALSP 376 + P PA P + P+ PTT E+ P+ TTP +P Sbjct: 594 PTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTP 653 Query: 377 SGQPSSSATEVVLRTRTASEGSEQPKKRASIQRTSAPPSRPPPPRATASPRPSSGNIP-- 434 +P+ + E T + PK+ A P+ P P A +P+ ++ P Sbjct: 654 E-EPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEP-APTTPKETAPTTPKG 711 Query: 435 SSPTASGGGSPTSPRAS-----LGTGTASPRTSLEVSPNPEPPEKPVRTPEAKENENIHN 489 ++PT +PT+P+ T T P ++ P P P+ T KE Sbjct: 712 TAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPT-TPKEPAPTTP 770 Query: 490 QNPEELCTSPTLMTSQVASEPGEAKKMEDKEKDNKLISANSSEGQDQLQVSMVPENNNLT 549 + P T T+ P KK KE +S D+ + E T Sbjct: 771 KEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTT 830 Query: 550 APEP 553 EP Sbjct: 831 PKEP 834 Score = 43.1 bits (100), Expect = 7e-04 Identities = 56/275 (20%), Positives = 96/275 (34%), Gaps = 23/275 (8%) Query: 263 SPPVRTATVSSPLTSPTSPSTLSLKSESESVSATEDLAPDAAQGEDNSEIKELLEEEEIE 322 +PP T+ VS+P T+ P+T+ + + + + P A + + Sbjct: 849 TPPPTTSEVSTPTTTK-EPTTIHKSPDESTPELSAEPTPKALENSPKEPGVPTTKTPAAT 907 Query: 323 KEGSEASSSEE--DEPLPACNGPAQAQPSPTTERAKSQEEVLPSSTTPSPGGALSPSGQP 380 K ++ ++ + L A P T E A + E+ S T + S + Q Sbjct: 908 KPEMTTTAKDKTTERDLRTTPETTTAAPKMTKETATTTEKTTESKITATTTQVTSTTTQD 967 Query: 381 SSSATEVVLRTRTASEGSEQPKKRASIQRTSAPPSRPPPPRATASPRPSSGNIPSSPTAS 440 ++ L+T T + KK + P P+ A+ ++ P PT Sbjct: 968 TTPFKITTLKTTTLAPKVTTTKKTITTTEIMNKPEETAKPKDRATNSKATTPKPQKPTK- 1026 Query: 441 GGGSPTSPRASLGTGTASPRTSLEVSPNPEPPEKPVRTP-EAKENENIHNQNPEELCTSP 499 +P P T T P+T V KP TP K + NP Sbjct: 1027 ---APKKP-----TSTKKPKTMPRV-------RKPKTTPTPRKMTSTMPELNPTSRIAEA 1071 Query: 500 TLMTSQVASEPGEAKKMEDKEKDNKLISANSSEGQ 534 L T+ ++ +K +E K A +EG+ Sbjct: 1072 MLQTTTRPNQTPNSKLVEVNPKSE---DAGGAEGE 1103 Score = 38.9 bits (89), Expect = 0.013 Identities = 60/300 (20%), Positives = 107/300 (35%), Gaps = 74/300 (24%) Query: 269 ATVSSPLTSPTSPSTLSLKSESESVSATEDLAPDAAQGEDNSEIKELLEEEEIEKEGSEA 328 A V +P + P+S S+++ +T +P + + + K+++E EEI +E S + Sbjct: 105 AEVHNPTSPPSSKKAPPPSGASQTIKSTTKRSP---KPPNKKKTKKVIESEEITEEHSVS 161 Query: 329 SSSEEDEPLPACNGPAQAQPSPTTERAKSQEEVLPSSTTPSPGGALSPSGQPSSSATEVV 388 + E S S SSS+T Sbjct: 162 ENQESS----------------------------------------SSSSSSSSSSTIRK 181 Query: 389 LRTRTASEGSEQPKKRASIQ-----RTSAPPSRPPPPRATASPRPSSGNI----PSSPTA 439 +++ S + + +K+ ++ RT P+ PP A +G+ P + T Sbjct: 182 IKSSKNSAANRELQKKLKVKDNKKNRTKKKPTPKPPVVDEAGSGLDNGDFKVTTPDTSTT 241 Query: 440 SGGGSPTSPRASLGTGTASPRTSLEVSPNPEPPEKPVRTPEAKENENIHNQNPEELCTSP 499 TSP+ + TA P NP P P + + ++ + E T Sbjct: 242 QHNKVSTSPKIT----TAKP-------INPRPSLPPNSDTSKETSLTVNKETTVE--TKE 288 Query: 500 TLMTSQVASEPGEAKKMEDKEKDNKLISANSSEGQDQLQVSMVPENNNLTAPEPQEEVST 559 T T++ S G+ K KE S + +D + P + L P P+ E +T Sbjct: 289 TTTTNKQTSTDGKEKTTSAKETQ----SIEKTSAKD-----LAPTSKVLAKPTPKAETTT 339 >gi|189181724 proteoglycan 4 isoform D [Homo sapiens] Length = 1270 Score = 61.2 bits (147), Expect = 2e-09 Identities = 72/324 (22%), Positives = 111/324 (34%), Gaps = 30/324 (9%) Query: 253 SSSSRRSLVISPPVRTATV-----SSPLTSPTSPSTLSLKSESESVSATEDLAPDAAQGE 307 S++ + SP + TA S P S TS T ++ +V E + Sbjct: 105 STTQHNKVSTSPKITTAKPINPRPSLPPNSDTSKETSLTVNKETTVETKETTTTNKQTST 164 Query: 308 DNSE-IKELLEEEEIEKEGSE---ASSSEEDEPLPACN----GPAQA---QPSPTTERAK 356 D E E + IEK ++ +S +P P GPA +P+PTT + Sbjct: 165 DGKEKTTSAKETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKE- 223 Query: 357 SQEEVLPSSTTPSPGGALSPSGQPSSSATEVVLRTRTASEGSEQPKKRASIQRTSAPPSR 416 P+STTP + P++ T++A PK+ A P+ Sbjct: 224 ------PASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPT---TPKEPAPTTTKEPAPTT 274 Query: 417 PPPPRATASPRPSSGNIPSSPTASGGGSPTSPRASLGTGTASPRTSLEVSPNPEPPEKPV 476 P P T + P+ S+PT +PT+P+ T P + P P P++P Sbjct: 275 PKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEP- 333 Query: 477 RTPEAKENENIHNQNPEELCTSPTLMTSQVASEPGEAKKMEDKEKDNKLISANSSEGQDQ 536 P KE + P T+P EP E K S + + Sbjct: 334 -APTTKEPAPTTPKEPAP--TAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAP 390 Query: 537 LQVSMVPENNNLTAPEPQEEVSTS 560 P AP + T+ Sbjct: 391 TTTKSAPTTTKEPAPTTTKSAPTT 414 Score = 59.3 bits (142), Expect = 9e-09 Identities = 52/226 (23%), Positives = 87/226 (38%), Gaps = 15/226 (6%) Query: 265 PVRTATVSSPLTSPTSPSTLSLKSESESV------SATEDLAPDAAQGEDNS--EIKELL 316 P T T S+P T+P P+ + K + + + T++ AP + + E Sbjct: 247 PAPTTTKSAP-TTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTT 305 Query: 317 EEEEIEKEGSEASSSEEDEPLPACNGPAQAQPSPTTERAKSQEEVLPSSTTPSPGGALSP 376 ++ E + + EP P +P+PTT+ P+ T P +P Sbjct: 306 PKKPAPTTPKEPAPTTPKEPTPT----TPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTP 361 Query: 377 SGQPSSSATEVVLRTRTASEGSEQPKKRASIQRTSAPPSRPPPPRATASPRPSSGNIPSS 436 +P+ + + T T PK+ A SAP + P T P++ PS Sbjct: 362 K-EPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPS- 419 Query: 437 PTASGGGSPTSPRASLGTGTASPRTSLEVSPNPEPPEKPVRTPEAK 482 PT + +PT+P+ T P + P P P++P T K Sbjct: 420 PTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKK 465 Score = 56.6 bits (135), Expect = 6e-08 Identities = 46/217 (21%), Positives = 75/217 (34%), Gaps = 4/217 (1%) Query: 265 PVRTATVSSPLTSPTSPSTLSLKSESESVSATEDLAPDAAQGEDNSEIKELLEEEEIEKE 324 P T T T+P P+ + K + + + + P + +E Sbjct: 262 PAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTT 321 Query: 325 GSEASSSEEDEPLPACNGPAQAQPS-PTTERAKSQEEVLPSSTTPSPGGALSPSGQPSSS 383 E + + EP P PA P P K P P+ +P+ S Sbjct: 322 PKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPS 381 Query: 384 ATEVVLRTRTASEGSEQPKKRASIQRTSAPPSRP--PPPRATASPRPSSGNIPSSPTASG 441 T T ++ + K + T + P+ P P P T P P++ P +PT Sbjct: 382 PTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEP-APTTPK 440 Query: 442 GGSPTSPRASLGTGTASPRTSLEVSPNPEPPEKPVRT 478 +PT+P+ T P + P P P++P T Sbjct: 441 KPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPT 477 Score = 50.8 bits (120), Expect = 3e-06 Identities = 59/289 (20%), Positives = 99/289 (34%), Gaps = 19/289 (6%) Query: 250 KGLSSSSRRSLVISPPVRTATVSSPLTSPTSPSTLSLKSESESVSATEDLAPDAA----- 304 K S + + + T T T +T + +++S ++ +DLAP + Sbjct: 138 KETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAKP 197 Query: 305 --QGEDNSEIKELLEEEE-IEKEGSEASSSEEDEPLPACNGPAQA---QPSPTTERAKSQ 358 + E ++ L +E E +S+ EP P A +P+PTT ++ Sbjct: 198 TPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPT 257 Query: 359 EEVLPSSTTPSPGGALSPSGQPSSSATEVVLRTRTASEGSEQ-------PKKRASIQRTS 411 P+ TT +P +P+ + T+ T T S + PKK A Sbjct: 258 TPKEPAPTTTKEPAPTTPK-EPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKE 316 Query: 412 APPSRPPPPRATASPRPSSGNIPSSPTASGGGSPTSPRASLGTGTASPRTSLEVSPNPEP 471 P+ P P T P+ +PT +PT+P+ T P + P P Sbjct: 317 PAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTT 376 Query: 472 PEKPVRTPEAKENENIHNQNPEELCTSPTLMTSQVASEPGEAKKMEDKE 520 ++P T + P T + P E KE Sbjct: 377 TKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKE 425 Score = 50.1 bits (118), Expect = 6e-06 Identities = 56/222 (25%), Positives = 91/222 (40%), Gaps = 26/222 (11%) Query: 265 PVRTATVSSPLTS----PTSPSTLSLKSESESVSATEDLAPDAAQGEDNSEIKE---LLE 317 P T T S+P T+ PT+ + + S + T++ AP + + K+ Sbjct: 388 PAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTP 447 Query: 318 EEEIEKEGSEASSSEEDEPLPACNGPAQAQPSPTTERAKSQEEVLPSSTTPSPGGALSPS 377 +E E + + +P P +P+PTT K P TP+ L+P+ Sbjct: 448 KEPAPTTPKEPAPTTTKKPAPT----TPKEPAPTTP--KETAPTTPKKLTPTTPEKLAPT 501 Query: 378 G--QPSSSATEVVLRTRTASEGSEQPKKRASIQRTSAPPSRP--PPPRATASPRPSSGNI 433 +P+ + E + T P++ A +A P+ P P P P P++ Sbjct: 502 TPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKE 561 Query: 434 PSSPTASGGGSPTSPRASLGTGTASPRTSLEVSPNPEPPEKP 475 P+ PT +PT+P+ GTA P T E P P P+KP Sbjct: 562 PA-PTTPKETAPTTPK-----GTA-PTTLKE--PAPTTPKKP 594 Score = 50.1 bits (118), Expect = 6e-06 Identities = 68/283 (24%), Positives = 102/283 (36%), Gaps = 43/283 (15%) Query: 264 PPVRTATVSSPLT----SPTSPSTLSLKSESESVSAT-EDLAPDAAQGEDNSEIKELLEE 318 P T ++P T +PT+P + + E T ++ AP +G + +KE Sbjct: 530 PAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPT 589 Query: 319 EEIEKEGSEASSSEEDEPLPA-CNGPAQAQPSPTTERAKSQEEVLPSSTTPSPGGALSPS 377 + E + + EP C+ PA P T + P+ TTP +P Sbjct: 590 TPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKE----PAPTTPKEPAPTTPK 645 Query: 378 GQ------------PSSSATEVVLRTRTASEGSEQPKKRASIQRTSAPPSRP--PPPRAT 423 G P A + + T T S K A P+ P P P Sbjct: 646 GTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTP 705 Query: 424 ASPRPSSGNIPSSPTASGGGSPTSPRASLGTGTASPRTSLEVSPNPEPPEKPVR-TPEAK 482 P P++ P PT S +PT T T++ SP+ PE TP+A Sbjct: 706 KKPAPTTPETPP-PTTSEVSTPT---------TTKEPTTIHKSPDESTPELSAEPTPKAL 755 Query: 483 ENENIHNQNPEELCTSPTLMTSQVASEPGEAKKMEDKEKDNKL 525 EN +P+E PT T A++P +DK + L Sbjct: 756 EN------SPKEPGV-PTTKT-PAATKPEMTTTAKDKTTERDL 790 Score = 47.8 bits (112), Expect = 3e-05 Identities = 49/223 (21%), Positives = 80/223 (35%), Gaps = 38/223 (17%) Query: 265 PVRTATVSSPLTSPTSPSTLSLKSESESVSATEDLAPDAAQGEDNSEIKELLEEEEIEKE 324 P T T T+P P+ + KS + + T++ AP + + Sbjct: 372 PAPTTTKEPSPTTPKEPAPTTTKS---APTTTKEPAPTTTKSAPTTP------------- 415 Query: 325 GSEASSSEEDEPLPACNGPAQAQPSPTTERAKSQEEVLPSSTTPSPGGALSPSGQPSSSA 384 E S + EP P +P+PTT + P+ TTP +P +P+ + Sbjct: 416 -KEPSPTTTKEPAPT----TPKEPAPTTPKK-------PAPTTPKEPAPTTPK-EPAPTT 462 Query: 385 TEVVLRTRTASEGSEQPKKRASIQRTSAPPSRP-------PPPRATASPRPSSGNIPSSP 437 T+ T PK+ A P+ P P A +P + P P Sbjct: 463 TKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEP 522 Query: 438 TASGGG--SPTSPRASLGTGTASPRTSLEVSPNPEPPEKPVRT 478 T + +PT+P+A+ P + P P P++P T Sbjct: 523 TPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPT 565 Score = 43.9 bits (102), Expect = 4e-04 Identities = 69/304 (22%), Positives = 107/304 (35%), Gaps = 21/304 (6%) Query: 265 PVRTATVSSPLTSPTSPSTLSLKSESESVSATEDLAPDAAQGEDNSEIKELLEEEEIEKE 324 P T T S+P T+P PS + K + + ++ AP + + KE E Sbjct: 403 PAPTTTKSAP-TTPKEPSPTTTKEPAPTTP--KEPAPTTPKKPAPTTPKEPAPTTPKEPA 459 Query: 325 GSEASSSEEDEPL-PACNGPAQAQPS------PTT-ERAKSQEEVLPSSTTPSPGGALSP 376 + P PA P + P+ PTT E+ P+ TTP +P Sbjct: 460 PTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTP 519 Query: 377 SGQPSSSATEVVLRTRTASEGSEQPKKRASIQRTSAPPSRPPPPRATASPRPSSGNIP-- 434 +P+ + E T + PK+ A P+ P P A +P+ ++ P Sbjct: 520 E-EPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEP-APTTPKETAPTTPKG 577 Query: 435 SSPTASGGGSPTSPRAS-----LGTGTASPRTSLEVSPNPEPPEKPVRTPEAKENENIHN 489 ++PT +PT+P+ T T P ++ P P P+ T KE Sbjct: 578 TAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPT-TPKEPAPTTP 636 Query: 490 QNPEELCTSPTLMTSQVASEPGEAKKMEDKEKDNKLISANSSEGQDQLQVSMVPENNNLT 549 + P T T+ P KK KE +S D+ + E T Sbjct: 637 KEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTT 696 Query: 550 APEP 553 EP Sbjct: 697 PKEP 700 Score = 43.1 bits (100), Expect = 7e-04 Identities = 56/275 (20%), Positives = 96/275 (34%), Gaps = 23/275 (8%) Query: 263 SPPVRTATVSSPLTSPTSPSTLSLKSESESVSATEDLAPDAAQGEDNSEIKELLEEEEIE 322 +PP T+ VS+P T+ P+T+ + + + + P A + + Sbjct: 715 TPPPTTSEVSTPTTTK-EPTTIHKSPDESTPELSAEPTPKALENSPKEPGVPTTKTPAAT 773 Query: 323 KEGSEASSSEE--DEPLPACNGPAQAQPSPTTERAKSQEEVLPSSTTPSPGGALSPSGQP 380 K ++ ++ + L A P T E A + E+ S T + S + Q Sbjct: 774 KPEMTTTAKDKTTERDLRTTPETTTAAPKMTKETATTTEKTTESKITATTTQVTSTTTQD 833 Query: 381 SSSATEVVLRTRTASEGSEQPKKRASIQRTSAPPSRPPPPRATASPRPSSGNIPSSPTAS 440 ++ L+T T + KK + P P+ A+ ++ P PT Sbjct: 834 TTPFKITTLKTTTLAPKVTTTKKTITTTEIMNKPEETAKPKDRATNSKATTPKPQKPTK- 892 Query: 441 GGGSPTSPRASLGTGTASPRTSLEVSPNPEPPEKPVRTP-EAKENENIHNQNPEELCTSP 499 +P P T T P+T V KP TP K + NP Sbjct: 893 ---APKKP-----TSTKKPKTMPRV-------RKPKTTPTPRKMTSTMPELNPTSRIAEA 937 Query: 500 TLMTSQVASEPGEAKKMEDKEKDNKLISANSSEGQ 534 L T+ ++ +K +E K A +EG+ Sbjct: 938 MLQTTTRPNQTPNSKLVEVNPKSE---DAGGAEGE 969 >gi|189181722 proteoglycan 4 isoform C [Homo sapiens] Length = 1311 Score = 61.2 bits (147), Expect = 2e-09 Identities = 72/324 (22%), Positives = 111/324 (34%), Gaps = 30/324 (9%) Query: 253 SSSSRRSLVISPPVRTATV-----SSPLTSPTSPSTLSLKSESESVSATEDLAPDAAQGE 307 S++ + SP + TA S P S TS T ++ +V E + Sbjct: 146 STTQHNKVSTSPKITTAKPINPRPSLPPNSDTSKETSLTVNKETTVETKETTTTNKQTST 205 Query: 308 DNSE-IKELLEEEEIEKEGSE---ASSSEEDEPLPACN----GPAQA---QPSPTTERAK 356 D E E + IEK ++ +S +P P GPA +P+PTT + Sbjct: 206 DGKEKTTSAKETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKE- 264 Query: 357 SQEEVLPSSTTPSPGGALSPSGQPSSSATEVVLRTRTASEGSEQPKKRASIQRTSAPPSR 416 P+STTP + P++ T++A PK+ A P+ Sbjct: 265 ------PASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPT---TPKEPAPTTTKEPAPTT 315 Query: 417 PPPPRATASPRPSSGNIPSSPTASGGGSPTSPRASLGTGTASPRTSLEVSPNPEPPEKPV 476 P P T + P+ S+PT +PT+P+ T P + P P P++P Sbjct: 316 PKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEP- 374 Query: 477 RTPEAKENENIHNQNPEELCTSPTLMTSQVASEPGEAKKMEDKEKDNKLISANSSEGQDQ 536 P KE + P T+P EP E K S + + Sbjct: 375 -APTTKEPAPTTPKEPAP--TAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAP 431 Query: 537 LQVSMVPENNNLTAPEPQEEVSTS 560 P AP + T+ Sbjct: 432 TTTKSAPTTTKEPAPTTTKSAPTT 455 Score = 59.3 bits (142), Expect = 9e-09 Identities = 52/226 (23%), Positives = 87/226 (38%), Gaps = 15/226 (6%) Query: 265 PVRTATVSSPLTSPTSPSTLSLKSESESV------SATEDLAPDAAQGEDNS--EIKELL 316 P T T S+P T+P P+ + K + + + T++ AP + + E Sbjct: 288 PAPTTTKSAP-TTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTT 346 Query: 317 EEEEIEKEGSEASSSEEDEPLPACNGPAQAQPSPTTERAKSQEEVLPSSTTPSPGGALSP 376 ++ E + + EP P +P+PTT+ P+ T P +P Sbjct: 347 PKKPAPTTPKEPAPTTPKEPTPT----TPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTP 402 Query: 377 SGQPSSSATEVVLRTRTASEGSEQPKKRASIQRTSAPPSRPPPPRATASPRPSSGNIPSS 436 +P+ + + T T PK+ A SAP + P T P++ PS Sbjct: 403 K-EPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPS- 460 Query: 437 PTASGGGSPTSPRASLGTGTASPRTSLEVSPNPEPPEKPVRTPEAK 482 PT + +PT+P+ T P + P P P++P T K Sbjct: 461 PTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKK 506 Score = 56.6 bits (135), Expect = 6e-08 Identities = 46/217 (21%), Positives = 75/217 (34%), Gaps = 4/217 (1%) Query: 265 PVRTATVSSPLTSPTSPSTLSLKSESESVSATEDLAPDAAQGEDNSEIKELLEEEEIEKE 324 P T T T+P P+ + K + + + + P + +E Sbjct: 303 PAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTT 362 Query: 325 GSEASSSEEDEPLPACNGPAQAQPS-PTTERAKSQEEVLPSSTTPSPGGALSPSGQPSSS 383 E + + EP P PA P P K P P+ +P+ S Sbjct: 363 PKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPS 422 Query: 384 ATEVVLRTRTASEGSEQPKKRASIQRTSAPPSRP--PPPRATASPRPSSGNIPSSPTASG 441 T T ++ + K + T + P+ P P P T P P++ P +PT Sbjct: 423 PTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEP-APTTPK 481 Query: 442 GGSPTSPRASLGTGTASPRTSLEVSPNPEPPEKPVRT 478 +PT+P+ T P + P P P++P T Sbjct: 482 KPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPT 518 Score = 50.8 bits (120), Expect = 3e-06 Identities = 59/289 (20%), Positives = 99/289 (34%), Gaps = 19/289 (6%) Query: 250 KGLSSSSRRSLVISPPVRTATVSSPLTSPTSPSTLSLKSESESVSATEDLAPDAA----- 304 K S + + + T T T +T + +++S ++ +DLAP + Sbjct: 179 KETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAKP 238 Query: 305 --QGEDNSEIKELLEEEE-IEKEGSEASSSEEDEPLPACNGPAQA---QPSPTTERAKSQ 358 + E ++ L +E E +S+ EP P A +P+PTT ++ Sbjct: 239 TPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPT 298 Query: 359 EEVLPSSTTPSPGGALSPSGQPSSSATEVVLRTRTASEGSEQ-------PKKRASIQRTS 411 P+ TT +P +P+ + T+ T T S + PKK A Sbjct: 299 TPKEPAPTTTKEPAPTTPK-EPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKE 357 Query: 412 APPSRPPPPRATASPRPSSGNIPSSPTASGGGSPTSPRASLGTGTASPRTSLEVSPNPEP 471 P+ P P T P+ +PT +PT+P+ T P + P P Sbjct: 358 PAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTT 417 Query: 472 PEKPVRTPEAKENENIHNQNPEELCTSPTLMTSQVASEPGEAKKMEDKE 520 ++P T + P T + P E KE Sbjct: 418 TKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKE 466 Score = 50.1 bits (118), Expect = 6e-06 Identities = 56/222 (25%), Positives = 91/222 (40%), Gaps = 26/222 (11%) Query: 265 PVRTATVSSPLTS----PTSPSTLSLKSESESVSATEDLAPDAAQGEDNSEIKE---LLE 317 P T T S+P T+ PT+ + + S + T++ AP + + K+ Sbjct: 429 PAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTP 488 Query: 318 EEEIEKEGSEASSSEEDEPLPACNGPAQAQPSPTTERAKSQEEVLPSSTTPSPGGALSPS 377 +E E + + +P P +P+PTT K P TP+ L+P+ Sbjct: 489 KEPAPTTPKEPAPTTTKKPAPT----TPKEPAPTTP--KETAPTTPKKLTPTTPEKLAPT 542 Query: 378 G--QPSSSATEVVLRTRTASEGSEQPKKRASIQRTSAPPSRP--PPPRATASPRPSSGNI 433 +P+ + E + T P++ A +A P+ P P P P P++ Sbjct: 543 TPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKE 602 Query: 434 PSSPTASGGGSPTSPRASLGTGTASPRTSLEVSPNPEPPEKP 475 P+ PT +PT+P+ GTA P T E P P P+KP Sbjct: 603 PA-PTTPKETAPTTPK-----GTA-PTTLKE--PAPTTPKKP 635 Score = 50.1 bits (118), Expect = 6e-06 Identities = 68/283 (24%), Positives = 102/283 (36%), Gaps = 43/283 (15%) Query: 264 PPVRTATVSSPLT----SPTSPSTLSLKSESESVSAT-EDLAPDAAQGEDNSEIKELLEE 318 P T ++P T +PT+P + + E T ++ AP +G + +KE Sbjct: 571 PAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPT 630 Query: 319 EEIEKEGSEASSSEEDEPLPA-CNGPAQAQPSPTTERAKSQEEVLPSSTTPSPGGALSPS 377 + E + + EP C+ PA P T + P+ TTP +P Sbjct: 631 TPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKE----PAPTTPKEPAPTTPK 686 Query: 378 GQ------------PSSSATEVVLRTRTASEGSEQPKKRASIQRTSAPPSRP--PPPRAT 423 G P A + + T T S K A P+ P P P Sbjct: 687 GTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTP 746 Query: 424 ASPRPSSGNIPSSPTASGGGSPTSPRASLGTGTASPRTSLEVSPNPEPPEKPVR-TPEAK 482 P P++ P PT S +PT T T++ SP+ PE TP+A Sbjct: 747 KKPAPTTPETPP-PTTSEVSTPT---------TTKEPTTIHKSPDESTPELSAEPTPKAL 796 Query: 483 ENENIHNQNPEELCTSPTLMTSQVASEPGEAKKMEDKEKDNKL 525 EN +P+E PT T A++P +DK + L Sbjct: 797 EN------SPKEPGV-PTTKT-PAATKPEMTTTAKDKTTERDL 831 Score = 47.8 bits (112), Expect = 3e-05 Identities = 49/223 (21%), Positives = 80/223 (35%), Gaps = 38/223 (17%) Query: 265 PVRTATVSSPLTSPTSPSTLSLKSESESVSATEDLAPDAAQGEDNSEIKELLEEEEIEKE 324 P T T T+P P+ + KS + + T++ AP + + Sbjct: 413 PAPTTTKEPSPTTPKEPAPTTTKS---APTTTKEPAPTTTKSAPTTP------------- 456 Query: 325 GSEASSSEEDEPLPACNGPAQAQPSPTTERAKSQEEVLPSSTTPSPGGALSPSGQPSSSA 384 E S + EP P +P+PTT + P+ TTP +P +P+ + Sbjct: 457 -KEPSPTTTKEPAPT----TPKEPAPTTPKK-------PAPTTPKEPAPTTPK-EPAPTT 503 Query: 385 TEVVLRTRTASEGSEQPKKRASIQRTSAPPSRP-------PPPRATASPRPSSGNIPSSP 437 T+ T PK+ A P+ P P A +P + P P Sbjct: 504 TKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEP 563 Query: 438 TASGGG--SPTSPRASLGTGTASPRTSLEVSPNPEPPEKPVRT 478 T + +PT+P+A+ P + P P P++P T Sbjct: 564 TPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPT 606 Score = 43.9 bits (102), Expect = 4e-04 Identities = 69/304 (22%), Positives = 107/304 (35%), Gaps = 21/304 (6%) Query: 265 PVRTATVSSPLTSPTSPSTLSLKSESESVSATEDLAPDAAQGEDNSEIKELLEEEEIEKE 324 P T T S+P T+P PS + K + + ++ AP + + KE E Sbjct: 444 PAPTTTKSAP-TTPKEPSPTTTKEPAPTTP--KEPAPTTPKKPAPTTPKEPAPTTPKEPA 500 Query: 325 GSEASSSEEDEPL-PACNGPAQAQPS------PTT-ERAKSQEEVLPSSTTPSPGGALSP 376 + P PA P + P+ PTT E+ P+ TTP +P Sbjct: 501 PTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTP 560 Query: 377 SGQPSSSATEVVLRTRTASEGSEQPKKRASIQRTSAPPSRPPPPRATASPRPSSGNIP-- 434 +P+ + E T + PK+ A P+ P P A +P+ ++ P Sbjct: 561 E-EPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEP-APTTPKETAPTTPKG 618 Query: 435 SSPTASGGGSPTSPRAS-----LGTGTASPRTSLEVSPNPEPPEKPVRTPEAKENENIHN 489 ++PT +PT+P+ T T P ++ P P P+ T KE Sbjct: 619 TAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPT-TPKEPAPTTP 677 Query: 490 QNPEELCTSPTLMTSQVASEPGEAKKMEDKEKDNKLISANSSEGQDQLQVSMVPENNNLT 549 + P T T+ P KK KE +S D+ + E T Sbjct: 678 KEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTT 737 Query: 550 APEP 553 EP Sbjct: 738 PKEP 741 Score = 43.1 bits (100), Expect = 7e-04 Identities = 56/275 (20%), Positives = 96/275 (34%), Gaps = 23/275 (8%) Query: 263 SPPVRTATVSSPLTSPTSPSTLSLKSESESVSATEDLAPDAAQGEDNSEIKELLEEEEIE 322 +PP T+ VS+P T+ P+T+ + + + + P A + + Sbjct: 756 TPPPTTSEVSTPTTTK-EPTTIHKSPDESTPELSAEPTPKALENSPKEPGVPTTKTPAAT 814 Query: 323 KEGSEASSSEE--DEPLPACNGPAQAQPSPTTERAKSQEEVLPSSTTPSPGGALSPSGQP 380 K ++ ++ + L A P T E A + E+ S T + S + Q Sbjct: 815 KPEMTTTAKDKTTERDLRTTPETTTAAPKMTKETATTTEKTTESKITATTTQVTSTTTQD 874 Query: 381 SSSATEVVLRTRTASEGSEQPKKRASIQRTSAPPSRPPPPRATASPRPSSGNIPSSPTAS 440 ++ L+T T + KK + P P+ A+ ++ P PT Sbjct: 875 TTPFKITTLKTTTLAPKVTTTKKTITTTEIMNKPEETAKPKDRATNSKATTPKPQKPTK- 933 Query: 441 GGGSPTSPRASLGTGTASPRTSLEVSPNPEPPEKPVRTP-EAKENENIHNQNPEELCTSP 499 +P P T T P+T V KP TP K + NP Sbjct: 934 ---APKKP-----TSTKKPKTMPRV-------RKPKTTPTPRKMTSTMPELNPTSRIAEA 978 Query: 500 TLMTSQVASEPGEAKKMEDKEKDNKLISANSSEGQ 534 L T+ ++ +K +E K A +EG+ Sbjct: 979 MLQTTTRPNQTPNSKLVEVNPKSE---DAGGAEGE 1010 >gi|116284392 mucin 2 precursor [Homo sapiens] Length = 5179 Score = 59.7 bits (143), Expect = 7e-09 Identities = 55/251 (21%), Positives = 91/251 (36%), Gaps = 24/251 (9%) Query: 263 SPPVRTATVSSPLTSPTSPSTLSLKSESESVSATEDLAPDAAQGEDNSEIKELLEEEEIE 322 SPP T T P T+P+ P+T + + + + P + Sbjct: 1485 SPPTTTTTTPPPTTTPSPPTTTPITPPASTTTLPPTTTPSPPTTTTTTPPPTTTPSPPTT 1544 Query: 323 KEGSEASSSEEDEPLPACNGPAQAQPSPTTERAKSQEEVLPSSTTPSPGGALSPSGQPSS 382 + +S+ P + P P+ TT + P++TTPSP + + P++ Sbjct: 1545 TPITPPTSTTTLPPTTTPSPP----PTTTTTPPPTTTPSPPTTTTPSPPTITTTTPPPTT 1600 Query: 383 SATEVVLRTRTASEGSEQPKKRASIQRTSAPPSRPP------PPRATASPRPSSGNIPSS 436 + + T T P + + P PP PP T SP P++ P Sbjct: 1601 TPSPPTTTTTT-------PPPTTTPSPPTTTPITPPTSTTTLPPTTTPSPPPTTTTTPPP 1653 Query: 437 PTASGGGSPTSPRASLGTGTASPRTSLEVSP---NPEPPEKPVRTPEAKENENIHNQNPE 493 T + T+P + T T P T+ SP P PP + TP + +P Sbjct: 1654 TTTPSPPTTTTPSPPITTTTTPPPTTTPSSPITTTPSPPTTTMTTPSPTTTPS----SPI 1709 Query: 494 ELCTSPTLMTS 504 T+P+ T+ Sbjct: 1710 TTTTTPSSTTT 1720 Score = 58.5 bits (140), Expect = 2e-08 Identities = 54/219 (24%), Positives = 77/219 (35%), Gaps = 14/219 (6%) Query: 263 SPPVRTATVSSPLTSPTSPSTLS---LKSESESVSATEDLAPDAAQGEDNSEIKELLEEE 319 SPP+ T T P T+P+ P+T + S + T P + Sbjct: 1455 SPPISTTTTPPPTTTPSPPTTTPSPPTTTPSPPTTTTTTPPPTTTPSPPTTT-------- 1506 Query: 320 EIEKEGSEASSSEEDEPLPACNGPAQAQPSPTTERAKSQEEVLPSSTTPSPGGALSPSGQ 379 I S + P P P+ T + P+STT P +PS Sbjct: 1507 PITPPASTTTLPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPTSTTTLPP-TTTPSPP 1565 Query: 380 PSSSATEVVLRTRTASEGSEQPKKRASIQRTSAPPSRPPPPRATASPRPSSGNIPSSPTA 439 P+++ T T T S + +I T+ PP+ P P T + P PS PT Sbjct: 1566 PTTTTTPPP--TTTPSPPTTTTPSPPTITTTTPPPTTTPSPPTTTTTTPPPTTTPSPPTT 1623 Query: 440 SGGGSPTSPRASLGTGTASPRTSLEVSPNPEPPEKPVRT 478 + PTS T T SP + +P P P T Sbjct: 1624 TPITPPTSTTTLPPTTTPSPPPTTTTTPPPTTTPSPPTT 1662 Score = 54.7 bits (130), Expect = 2e-07 Identities = 58/228 (25%), Positives = 81/228 (35%), Gaps = 36/228 (15%) Query: 263 SPPVRTATVSSPLTSPTSPSTLS-----LKSESESVSATEDLAPDAAQGEDNSEIKELLE 317 SPP T T P T+P+ P T + + S +S T P + Sbjct: 1423 SPPTTTTTTPPPTTTPSPPITTTTTPPPTTTPSPPISTTTTPPPTTTPSPPTT------- 1475 Query: 318 EEEIEKEGSEASSSEEDEPLPACNGPAQAQPSPTTE---RAKSQEEVLPSSTTPSPGGAL 374 S +++ P PSP T + LP +TTPSP Sbjct: 1476 ------TPSPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPASTTTLPPTTTPSPPTTT 1529 Query: 375 SPSGQPSSSATEVVLRTRTASEGSEQPKKRASIQRTSAPPSRP-PPPRATASPRPSSGNI 433 + + P T T S + P + T P + P PPP T +P P++ Sbjct: 1530 TTTPPP----------TTTPSPPTTTPITPPTSTTTLPPTTTPSPPPTTTTTPPPTT--T 1577 Query: 434 PSSPTASGGGSPT-SPRASLGTGTASPRTSLEVSPNP-EPPEKPVRTP 479 PS PT + PT + T T SP T+ +P P P P TP Sbjct: 1578 PSPPTTTTPSPPTITTTTPPPTTTPSPPTTTTTTPPPTTTPSPPTTTP 1625 Score = 51.6 bits (122), Expect = 2e-06 Identities = 41/155 (26%), Positives = 61/155 (39%), Gaps = 9/155 (5%) Query: 326 SEASSSEEDEPLPACNGPAQAQPSPTTERAKSQEEVLPSSTTPSPGGALSPSGQPSSSAT 385 S +++ P P PSP T + P +TTPSP + + P+++ + Sbjct: 1400 SPPTTTPSPPPTSTTTLPPTTTPSPPTTTTTTP----PPTTTPSPPITTTTTPPPTTTPS 1455 Query: 386 EVVLRTRTASEGSEQPKKRASIQRTSAPPSRPPPPRATASPRPSSGNIPSSPTASGGGSP 445 + T T + P + T +PP+ P P T + P PS PT + P Sbjct: 1456 PPI-STTTTPPPTTTPSPPTT---TPSPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPP 1511 Query: 446 TSPRASLGTGTASPRTSLEVSPNP-EPPEKPVRTP 479 S T T SP T+ +P P P P TP Sbjct: 1512 ASTTTLPPTTTPSPPTTTTTTPPPTTTPSPPTTTP 1546 Score = 51.6 bits (122), Expect = 2e-06 Identities = 53/219 (24%), Positives = 80/219 (36%), Gaps = 22/219 (10%) Query: 263 SPPVRTATVSSPLTSPTSPSTLSLKSESESVSATEDLAPDAAQGEDNSEIKELLEEEEIE 322 SPP T T P T+P+ P+T + S T P + Sbjct: 1563 SPPPTTTTTPPPTTTPSPPTTTT---PSPPTITTTTPPPTTTPSPPTTTTTT-------- 1611 Query: 323 KEGSEASSSEEDEPLPACNGPAQAQPSPTTERAKSQEEVLPSSTTPSPGGALSPSGQPSS 382 + S P+ P+ T + P +TTPSP +PS P + Sbjct: 1612 PPPTTTPSPPTTTPITPPTSTTTLPPTTTPSPPPTTTTTPPPTTTPSPPTTTTPS-PPIT 1670 Query: 383 SATEVVLRTRTASEGSEQPKKRASIQRTSAPPSRPPPPRATASPRPSSGNIPSSP----- 437 + T T +S + P + T +P + P P T + PSS PS P Sbjct: 1671 TTTTPPPTTTPSSPITTTPSPPTTTMTTPSPTTTPSSP-ITTTTTPSSTTTPSPPPTTMT 1729 Query: 438 TASGGGSPTSPRASL----GTGTASPRTSLEVSPNPEPP 472 T S +P+ P ++ T T+SP T+ + P+ PP Sbjct: 1730 TPSPTTTPSPPTTTMTTLPPTTTSSPLTTTPLPPSITPP 1768 Score = 48.9 bits (115), Expect = 1e-05 Identities = 63/279 (22%), Positives = 92/279 (32%), Gaps = 47/279 (16%) Query: 250 KGLSSSSRRSLVISPPVRTATVSSPLTSPTSPSTLSLK-----SESESVSATEDLAPDAA 304 K +++ S + SPP + T P T+P+ P+T + + S ++ T P Sbjct: 1394 KCITTPSPPTTTPSPPPTSTTTLPPTTTPSPPTTTTTTPPPTTTPSPPITTTTTPPPTTT 1453 Query: 305 QGEDNSEIKELLEEEEIEKEGSEASSSEEDEPLPACNGPAQAQPSPTTERAKSQEEVLPS 364 S + + P P PSP T + P Sbjct: 1454 PSPPISTT-------------TTPPPTTTPSPPTTTPSPPTTTPSPPTTTTTTP----PP 1496 Query: 365 STTPSPGGALSPSGQPSSSATEVVLRTRTASEGSEQPKKRASIQRTSAPPSRPPPPRAT- 423 +TTPSP +P P+S+ T T P + T P + P PP T Sbjct: 1497 TTTPSPP-TTTPITPPASTTTLPPTTT---------PSPPTTTTTTPPPTTTPSPPTTTP 1546 Query: 424 ASPRPSSGNIPSSPTASGGGSPTSPRASLGTGTASPRTSLEVSP------------NPEP 471 +P S+ +P PT + PT+ T T SP T+ SP P P Sbjct: 1547 ITPPTSTTTLP--PTTTPSPPPTTTTTPPPTTTPSPPTTTTPSPPTITTTTPPPTTTPSP 1604 Query: 472 PEKPVRTPEAKENENIHNQNPEELCTSPTLMTSQVASEP 510 P TP + P TS T + P Sbjct: 1605 PTTTTTTPPPTTTPSPPTTTPITPPTSTTTLPPTTTPSP 1643 Score = 48.5 bits (114), Expect = 2e-05 Identities = 46/228 (20%), Positives = 74/228 (32%), Gaps = 21/228 (9%) Query: 263 SPPVRTATVSSPLTSPTSPSTLSLKSESESVSATEDLAPDAAQGEDNSEIKELLEEEEIE 322 SPP T T P T+P+ P+T + + + + P + Sbjct: 1524 SPPTTTTTTPPPTTTPSPPTTTPITPPTSTTTLPPTTTPSPPPTTTTTPPPTTTPSPPTT 1583 Query: 323 KEGSEASSSEEDEPLPACNGP---AQAQPSPTTERAK---------SQEEVLPSSTTPSP 370 S + + P P P PTT + + LP +TTPSP Sbjct: 1584 TTPSPPTITTTTPPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPTSTTTLPPTTTPSP 1643 Query: 371 GGALSPSGQPSSSATEVVLRTRTASEGSEQPKKRASIQRTSAPPSRPPPPRATASPRPSS 430 + + P+++ + T P + T P + P P T P++ Sbjct: 1644 PPTTTTTPPPTTTPSPPTTTT---------PSPPITTTTTPPPTTTPSSPITTTPSPPTT 1694 Query: 431 GNIPSSPTASGGGSPTSPRASLGTGTASPRTSLEVSPNPEPPEKPVRT 478 SPT + T+ T T SP + +P+P P T Sbjct: 1695 TMTTPSPTTTPSSPITTTTTPSSTTTPSPPPTTMTTPSPTTTPSPPTT 1742 Score = 46.6 bits (109), Expect = 6e-05 Identities = 54/246 (21%), Positives = 85/246 (34%), Gaps = 31/246 (12%) Query: 265 PVRTATVSSPLTSPTSPSTLSLKSESESVSATEDLAPDAAQGEDNSEIKELLEEEEIEKE 324 P+ T T +P +PT T + + + + T P Q + I Sbjct: 4016 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI------------ 4063 Query: 325 GSEASSSEEDEPLPACNGPAQAQPSPTTERAKSQEEVLPSSTTPSPGGALSPSGQPSSSA 384 +++ P P G +PTT + V P TP+P G +P+ P ++ Sbjct: 4064 ----TTTTTVTPTPTPTGTQ----TPTTTPITTTTTVTP---TPTPTGTQTPTTTPITTT 4112 Query: 385 TEVVLRTRTASEGSEQPKKRASIQRTSAPPSRPPPPRATASPRPSSGNIPSSPTASGGGS 444 T V G++ P T+ P+ P T + P + +PT + G+ Sbjct: 4113 TTVT--PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 4170 Query: 445 PTSPRASLGTGTASPRTSLEVSPNPEPPEKPVRTPEAKENENIHNQNPEELCTSPTLMTS 504 T + T T T PP P A+ + N PE S T TS Sbjct: 4171 QTPTTTPITTTTTVTPTPTPTGTQTGPPTHTSTAPIAELTTS--NPPPE----SSTPQTS 4224 Query: 505 QVASEP 510 + S P Sbjct: 4225 RSTSSP 4230 Score = 46.2 bits (108), Expect = 8e-05 Identities = 43/201 (21%), Positives = 71/201 (35%), Gaps = 31/201 (15%) Query: 263 SPPVRTATVSSPLTSPTSPSTLSLKSESESVSATEDLAPDAAQGEDNSEIKELLEEEEIE 322 SPP T T P T+P+ P+T + + + + P Sbjct: 1603 SPPTTTTTTPPPTTTPSPPTTTPITPPTSTTTLPPTTTPSPPP----------------- 1645 Query: 323 KEGSEASSSEEDEPLPACNGPAQAQPSP----TTERAKSQEEVLPSSTTPSPGGALSPSG 378 +++ P + P PSP TT + P +TTPSP + Sbjct: 1646 ------TTTTTPPPTTTPSPPTTTTPSPPITTTTTPPPTTTPSSPITTTPSPPTTTMTTP 1699 Query: 379 QPSSSATEVVLRTRTASEGSEQPKKRASIQRTSAPPSRPPPPRATAS---PRPSSGNIPS 435 P+++ + + T T S + P + T +P + P PP T + P +S + + Sbjct: 1700 SPTTTPSSPITTTTTPSS-TTTPSPPPTTMTTPSPTTTPSPPTTTMTTLPPTTTSSPLTT 1758 Query: 436 SPTASGGGSPTSPRASLGTGT 456 +P PT S T T Sbjct: 1759 TPLPPSITPPTFSPFSTTTPT 1779 Score = 45.8 bits (107), Expect = 1e-04 Identities = 59/268 (22%), Positives = 95/268 (35%), Gaps = 48/268 (17%) Query: 265 PVRTATVSSPLTSPTSPSTLSLKSESESVSATEDLAPDAAQGEDNSEIKELLEEEEIEKE 324 P+ T T +P +PT T + + + + T P Q + I Sbjct: 1923 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI------------ 1970 Query: 325 GSEASSSEEDEPLPACNGPAQAQPSPTTERAKSQEEVLPSSTTPSPGGALSPSGQPSSSA 384 +++ P P G +PTT + V P TP+P G +P+ P ++ Sbjct: 1971 ----TTTTTVTPTPTPTGTQ----TPTTTPITTTTTVTP---TPTPTGTQTPTTTPITTT 2019 Query: 385 TEVVLRTRTASEGSEQPKKRASIQRTSAPPSRPPPPRA---TASPRPSSGNIPSSPTASG 441 T V T T + Q I T+ P P T +P ++ + +PT +G Sbjct: 2020 TTV---TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG 2076 Query: 442 GGSPTSPRASLGT---------GTASP-----RTSLEVSPNPEP--PEKPVRTPEAKENE 485 +PT+ + T GT +P T+ V+P P P + P TP Sbjct: 2077 TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 2136 Query: 486 NIHNQNP---EELCTSPTLMTSQVASEP 510 P + T+P T+ V P Sbjct: 2137 VTPTPTPTGTQTPTTTPITTTTTVTPTP 2164 Score = 45.8 bits (107), Expect = 1e-04 Identities = 59/268 (22%), Positives = 95/268 (35%), Gaps = 48/268 (17%) Query: 265 PVRTATVSSPLTSPTSPSTLSLKSESESVSATEDLAPDAAQGEDNSEIKELLEEEEIEKE 324 P+ T T +P +PT T + + + + T P Q + I Sbjct: 1992 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI------------ 2039 Query: 325 GSEASSSEEDEPLPACNGPAQAQPSPTTERAKSQEEVLPSSTTPSPGGALSPSGQPSSSA 384 +++ P P G +PTT + V P TP+P G +P+ P ++ Sbjct: 2040 ----TTTTTVTPTPTPTGTQ----TPTTTPITTTTTVTP---TPTPTGTQTPTTTPITTT 2088 Query: 385 TEVVLRTRTASEGSEQPKKRASIQRTSAPPSRPPPPRA---TASPRPSSGNIPSSPTASG 441 T V T T + Q I T+ P P T +P ++ + +PT +G Sbjct: 2089 TTV---TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG 2145 Query: 442 GGSPTSPRASLGT---------GTASP-----RTSLEVSPNPEP--PEKPVRTPEAKENE 485 +PT+ + T GT +P T+ V+P P P + P TP Sbjct: 2146 TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 2205 Query: 486 NIHNQNP---EELCTSPTLMTSQVASEP 510 P + T+P T+ V P Sbjct: 2206 VTPTPTPTGTQTPTTTPITTTTTVTPTP 2233 Score = 45.8 bits (107), Expect = 1e-04 Identities = 59/268 (22%), Positives = 95/268 (35%), Gaps = 48/268 (17%) Query: 265 PVRTATVSSPLTSPTSPSTLSLKSESESVSATEDLAPDAAQGEDNSEIKELLEEEEIEKE 324 P+ T T +P +PT T + + + + T P Q + I Sbjct: 2061 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI------------ 2108 Query: 325 GSEASSSEEDEPLPACNGPAQAQPSPTTERAKSQEEVLPSSTTPSPGGALSPSGQPSSSA 384 +++ P P G +PTT + V P TP+P G +P+ P ++ Sbjct: 2109 ----TTTTTVTPTPTPTGTQ----TPTTTPITTTTTVTP---TPTPTGTQTPTTTPITTT 2157 Query: 385 TEVVLRTRTASEGSEQPKKRASIQRTSAPPSRPPPPRA---TASPRPSSGNIPSSPTASG 441 T V T T + Q I T+ P P T +P ++ + +PT +G Sbjct: 2158 TTV---TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG 2214 Query: 442 GGSPTSPRASLGT---------GTASP-----RTSLEVSPNPEP--PEKPVRTPEAKENE 485 +PT+ + T GT +P T+ V+P P P + P TP Sbjct: 2215 TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 2274 Query: 486 NIHNQNP---EELCTSPTLMTSQVASEP 510 P + T+P T+ V P Sbjct: 2275 VTPTPTPTGTQTPTTTPITTTTTVTPTP 2302 Score = 45.8 bits (107), Expect = 1e-04 Identities = 59/268 (22%), Positives = 95/268 (35%), Gaps = 48/268 (17%) Query: 265 PVRTATVSSPLTSPTSPSTLSLKSESESVSATEDLAPDAAQGEDNSEIKELLEEEEIEKE 324 P+ T T +P +PT T + + + + T P Q + I Sbjct: 2130 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI------------ 2177 Query: 325 GSEASSSEEDEPLPACNGPAQAQPSPTTERAKSQEEVLPSSTTPSPGGALSPSGQPSSSA 384 +++ P P G +PTT + V P TP+P G +P+ P ++ Sbjct: 2178 ----TTTTTVTPTPTPTGTQ----TPTTTPITTTTTVTP---TPTPTGTQTPTTTPITTT 2226 Query: 385 TEVVLRTRTASEGSEQPKKRASIQRTSAPPSRPPPPRA---TASPRPSSGNIPSSPTASG 441 T V T T + Q I T+ P P T +P ++ + +PT +G Sbjct: 2227 TTV---TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG 2283 Query: 442 GGSPTSPRASLGT---------GTASP-----RTSLEVSPNPEP--PEKPVRTPEAKENE 485 +PT+ + T GT +P T+ V+P P P + P TP Sbjct: 2284 TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 2343 Query: 486 NIHNQNP---EELCTSPTLMTSQVASEP 510 P + T+P T+ V P Sbjct: 2344 VTPTPTPTGTQTPTTTPITTTTTVTPTP 2371 Score = 45.8 bits (107), Expect = 1e-04 Identities = 59/268 (22%), Positives = 95/268 (35%), Gaps = 48/268 (17%) Query: 265 PVRTATVSSPLTSPTSPSTLSLKSESESVSATEDLAPDAAQGEDNSEIKELLEEEEIEKE 324 P+ T T +P +PT T + + + + T P Q + I Sbjct: 2199 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI------------ 2246 Query: 325 GSEASSSEEDEPLPACNGPAQAQPSPTTERAKSQEEVLPSSTTPSPGGALSPSGQPSSSA 384 +++ P P G +PTT + V P TP+P G +P+ P ++ Sbjct: 2247 ----TTTTTVTPTPTPTGTQ----TPTTTPITTTTTVTP---TPTPTGTQTPTTTPITTT 2295 Query: 385 TEVVLRTRTASEGSEQPKKRASIQRTSAPPSRPPPPRA---TASPRPSSGNIPSSPTASG 441 T V T T + Q I T+ P P T +P ++ + +PT +G Sbjct: 2296 TTV---TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG 2352 Query: 442 GGSPTSPRASLGT---------GTASP-----RTSLEVSPNPEP--PEKPVRTPEAKENE 485 +PT+ + T GT +P T+ V+P P P + P TP Sbjct: 2353 TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 2412 Query: 486 NIHNQNP---EELCTSPTLMTSQVASEP 510 P + T+P T+ V P Sbjct: 2413 VTPTPTPTGTQTPTTTPITTTTTVTPTP 2440 Score = 45.8 bits (107), Expect = 1e-04 Identities = 59/268 (22%), Positives = 95/268 (35%), Gaps = 48/268 (17%) Query: 265 PVRTATVSSPLTSPTSPSTLSLKSESESVSATEDLAPDAAQGEDNSEIKELLEEEEIEKE 324 P+ T T +P +PT T + + + + T P Q + I Sbjct: 2268 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI------------ 2315 Query: 325 GSEASSSEEDEPLPACNGPAQAQPSPTTERAKSQEEVLPSSTTPSPGGALSPSGQPSSSA 384 +++ P P G +PTT + V P TP+P G +P+ P ++ Sbjct: 2316 ----TTTTTVTPTPTPTGTQ----TPTTTPITTTTTVTP---TPTPTGTQTPTTTPITTT 2364 Query: 385 TEVVLRTRTASEGSEQPKKRASIQRTSAPPSRPPPPRA---TASPRPSSGNIPSSPTASG 441 T V T T + Q I T+ P P T +P ++ + +PT +G Sbjct: 2365 TTV---TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG 2421 Query: 442 GGSPTSPRASLGT---------GTASP-----RTSLEVSPNPEP--PEKPVRTPEAKENE 485 +PT+ + T GT +P T+ V+P P P + P TP Sbjct: 2422 TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 2481 Query: 486 NIHNQNP---EELCTSPTLMTSQVASEP 510 P + T+P T+ V P Sbjct: 2482 VTPTPTPTGTQTPTTTPITTTTTVTPTP 2509 Score = 45.8 bits (107), Expect = 1e-04 Identities = 59/268 (22%), Positives = 95/268 (35%), Gaps = 48/268 (17%) Query: 265 PVRTATVSSPLTSPTSPSTLSLKSESESVSATEDLAPDAAQGEDNSEIKELLEEEEIEKE 324 P+ T T +P +PT T + + + + T P Q + I Sbjct: 2337 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI------------ 2384 Query: 325 GSEASSSEEDEPLPACNGPAQAQPSPTTERAKSQEEVLPSSTTPSPGGALSPSGQPSSSA 384 +++ P P G +PTT + V P TP+P G +P+ P ++ Sbjct: 2385 ----TTTTTVTPTPTPTGTQ----TPTTTPITTTTTVTP---TPTPTGTQTPTTTPITTT 2433 Query: 385 TEVVLRTRTASEGSEQPKKRASIQRTSAPPSRPPPPRA---TASPRPSSGNIPSSPTASG 441 T V T T + Q I T+ P P T +P ++ + +PT +G Sbjct: 2434 TTV---TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG 2490 Query: 442 GGSPTSPRASLGT---------GTASP-----RTSLEVSPNPEP--PEKPVRTPEAKENE 485 +PT+ + T GT +P T+ V+P P P + P TP Sbjct: 2491 TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 2550 Query: 486 NIHNQNP---EELCTSPTLMTSQVASEP 510 P + T+P T+ V P Sbjct: 2551 VTPTPTPTGTQTPTTTPITTTTTVTPTP 2578 Score = 45.8 bits (107), Expect = 1e-04 Identities = 59/268 (22%), Positives = 95/268 (35%), Gaps = 48/268 (17%) Query: 265 PVRTATVSSPLTSPTSPSTLSLKSESESVSATEDLAPDAAQGEDNSEIKELLEEEEIEKE 324 P+ T T +P +PT T + + + + T P Q + I Sbjct: 2406 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI------------ 2453 Query: 325 GSEASSSEEDEPLPACNGPAQAQPSPTTERAKSQEEVLPSSTTPSPGGALSPSGQPSSSA 384 +++ P P G +PTT + V P TP+P G +P+ P ++ Sbjct: 2454 ----TTTTTVTPTPTPTGTQ----TPTTTPITTTTTVTP---TPTPTGTQTPTTTPITTT 2502 Query: 385 TEVVLRTRTASEGSEQPKKRASIQRTSAPPSRPPPPRA---TASPRPSSGNIPSSPTASG 441 T V T T + Q I T+ P P T +P ++ + +PT +G Sbjct: 2503 TTV---TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG 2559 Query: 442 GGSPTSPRASLGT---------GTASP-----RTSLEVSPNPEP--PEKPVRTPEAKENE 485 +PT+ + T GT +P T+ V+P P P + P TP Sbjct: 2560 TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 2619 Query: 486 NIHNQNP---EELCTSPTLMTSQVASEP 510 P + T+P T+ V P Sbjct: 2620 VTPTPTPTGTQTPTTTPITTTTTVTPTP 2647 Score = 45.8 bits (107), Expect = 1e-04 Identities = 59/268 (22%), Positives = 95/268 (35%), Gaps = 48/268 (17%) Query: 265 PVRTATVSSPLTSPTSPSTLSLKSESESVSATEDLAPDAAQGEDNSEIKELLEEEEIEKE 324 P+ T T +P +PT T + + + + T P Q + I Sbjct: 2475 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI------------ 2522 Query: 325 GSEASSSEEDEPLPACNGPAQAQPSPTTERAKSQEEVLPSSTTPSPGGALSPSGQPSSSA 384 +++ P P G +PTT + V P TP+P G +P+ P ++ Sbjct: 2523 ----TTTTTVTPTPTPTGTQ----TPTTTPITTTTTVTP---TPTPTGTQTPTTTPITTT 2571 Query: 385 TEVVLRTRTASEGSEQPKKRASIQRTSAPPSRPPPPRA---TASPRPSSGNIPSSPTASG 441 T V T T + Q I T+ P P T +P ++ + +PT +G Sbjct: 2572 TTV---TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG 2628 Query: 442 GGSPTSPRASLGT---------GTASP-----RTSLEVSPNPEP--PEKPVRTPEAKENE 485 +PT+ + T GT +P T+ V+P P P + P TP Sbjct: 2629 TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 2688 Query: 486 NIHNQNP---EELCTSPTLMTSQVASEP 510 P + T+P T+ V P Sbjct: 2689 VTPTPTPTGTQTPTTTPITTTTTVTPTP 2716 Score = 45.8 bits (107), Expect = 1e-04 Identities = 59/268 (22%), Positives = 95/268 (35%), Gaps = 48/268 (17%) Query: 265 PVRTATVSSPLTSPTSPSTLSLKSESESVSATEDLAPDAAQGEDNSEIKELLEEEEIEKE 324 P+ T T +P +PT T + + + + T P Q + I Sbjct: 2544 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI------------ 2591 Query: 325 GSEASSSEEDEPLPACNGPAQAQPSPTTERAKSQEEVLPSSTTPSPGGALSPSGQPSSSA 384 +++ P P G +PTT + V P TP+P G +P+ P ++ Sbjct: 2592 ----TTTTTVTPTPTPTGTQ----TPTTTPITTTTTVTP---TPTPTGTQTPTTTPITTT 2640 Query: 385 TEVVLRTRTASEGSEQPKKRASIQRTSAPPSRPPPPRA---TASPRPSSGNIPSSPTASG 441 T V T T + Q I T+ P P T +P ++ + +PT +G Sbjct: 2641 TTV---TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG 2697 Query: 442 GGSPTSPRASLGT---------GTASP-----RTSLEVSPNPEP--PEKPVRTPEAKENE 485 +PT+ + T GT +P T+ V+P P P + P TP Sbjct: 2698 TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 2757 Query: 486 NIHNQNP---EELCTSPTLMTSQVASEP 510 P + T+P T+ V P Sbjct: 2758 VTPTPTPTGTQTPTTTPITTTTTVTPTP 2785 Score = 45.8 bits (107), Expect = 1e-04 Identities = 59/268 (22%), Positives = 95/268 (35%), Gaps = 48/268 (17%) Query: 265 PVRTATVSSPLTSPTSPSTLSLKSESESVSATEDLAPDAAQGEDNSEIKELLEEEEIEKE 324 P+ T T +P +PT T + + + + T P Q + I Sbjct: 2613 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI------------ 2660 Query: 325 GSEASSSEEDEPLPACNGPAQAQPSPTTERAKSQEEVLPSSTTPSPGGALSPSGQPSSSA 384 +++ P P G +PTT + V P TP+P G +P+ P ++ Sbjct: 2661 ----TTTTTVTPTPTPTGTQ----TPTTTPITTTTTVTP---TPTPTGTQTPTTTPITTT 2709 Query: 385 TEVVLRTRTASEGSEQPKKRASIQRTSAPPSRPPPPRA---TASPRPSSGNIPSSPTASG 441 T V T T + Q I T+ P P T +P ++ + +PT +G Sbjct: 2710 TTV---TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG 2766 Query: 442 GGSPTSPRASLGT---------GTASP-----RTSLEVSPNPEP--PEKPVRTPEAKENE 485 +PT+ + T GT +P T+ V+P P P + P TP Sbjct: 2767 TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 2826 Query: 486 NIHNQNP---EELCTSPTLMTSQVASEP 510 P + T+P T+ V P Sbjct: 2827 VTPTPTPTGTQTPTTTPITTTTTVTPTP 2854 Score = 45.8 bits (107), Expect = 1e-04 Identities = 59/268 (22%), Positives = 95/268 (35%), Gaps = 48/268 (17%) Query: 265 PVRTATVSSPLTSPTSPSTLSLKSESESVSATEDLAPDAAQGEDNSEIKELLEEEEIEKE 324 P+ T T +P +PT T + + + + T P Q + I Sbjct: 2682 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI------------ 2729 Query: 325 GSEASSSEEDEPLPACNGPAQAQPSPTTERAKSQEEVLPSSTTPSPGGALSPSGQPSSSA 384 +++ P P G +PTT + V P TP+P G +P+ P ++ Sbjct: 2730 ----TTTTTVTPTPTPTGTQ----TPTTTPITTTTTVTP---TPTPTGTQTPTTTPITTT 2778 Query: 385 TEVVLRTRTASEGSEQPKKRASIQRTSAPPSRPPPPRA---TASPRPSSGNIPSSPTASG 441 T V T T + Q I T+ P P T +P ++ + +PT +G Sbjct: 2779 TTV---TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG 2835 Query: 442 GGSPTSPRASLGT---------GTASP-----RTSLEVSPNPEP--PEKPVRTPEAKENE 485 +PT+ + T GT +P T+ V+P P P + P TP Sbjct: 2836 TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 2895 Query: 486 NIHNQNP---EELCTSPTLMTSQVASEP 510 P + T+P T+ V P Sbjct: 2896 VTPTPTPTGTQTPTTTPITTTTTVTPTP 2923 Score = 45.8 bits (107), Expect = 1e-04 Identities = 59/268 (22%), Positives = 95/268 (35%), Gaps = 48/268 (17%) Query: 265 PVRTATVSSPLTSPTSPSTLSLKSESESVSATEDLAPDAAQGEDNSEIKELLEEEEIEKE 324 P+ T T +P +PT T + + + + T P Q + I Sbjct: 2751 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI------------ 2798 Query: 325 GSEASSSEEDEPLPACNGPAQAQPSPTTERAKSQEEVLPSSTTPSPGGALSPSGQPSSSA 384 +++ P P G +PTT + V P TP+P G +P+ P ++ Sbjct: 2799 ----TTTTTVTPTPTPTGTQ----TPTTTPITTTTTVTP---TPTPTGTQTPTTTPITTT 2847 Query: 385 TEVVLRTRTASEGSEQPKKRASIQRTSAPPSRPPPPRA---TASPRPSSGNIPSSPTASG 441 T V T T + Q I T+ P P T +P ++ + +PT +G Sbjct: 2848 TTV---TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG 2904 Query: 442 GGSPTSPRASLGT---------GTASP-----RTSLEVSPNPEP--PEKPVRTPEAKENE 485 +PT+ + T GT +P T+ V+P P P + P TP Sbjct: 2905 TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 2964 Query: 486 NIHNQNP---EELCTSPTLMTSQVASEP 510 P + T+P T+ V P Sbjct: 2965 VTPTPTPTGTQTPTTTPITTTTTVTPTP 2992 Score = 45.8 bits (107), Expect = 1e-04 Identities = 59/268 (22%), Positives = 95/268 (35%), Gaps = 48/268 (17%) Query: 265 PVRTATVSSPLTSPTSPSTLSLKSESESVSATEDLAPDAAQGEDNSEIKELLEEEEIEKE 324 P+ T T +P +PT T + + + + T P Q + I Sbjct: 2820 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI------------ 2867 Query: 325 GSEASSSEEDEPLPACNGPAQAQPSPTTERAKSQEEVLPSSTTPSPGGALSPSGQPSSSA 384 +++ P P G +PTT + V P TP+P G +P+ P ++ Sbjct: 2868 ----TTTTTVTPTPTPTGTQ----TPTTTPITTTTTVTP---TPTPTGTQTPTTTPITTT 2916 Query: 385 TEVVLRTRTASEGSEQPKKRASIQRTSAPPSRPPPPRA---TASPRPSSGNIPSSPTASG 441 T V T T + Q I T+ P P T +P ++ + +PT +G Sbjct: 2917 TTV---TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG 2973 Query: 442 GGSPTSPRASLGT---------GTASP-----RTSLEVSPNPEP--PEKPVRTPEAKENE 485 +PT+ + T GT +P T+ V+P P P + P TP Sbjct: 2974 TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 3033 Query: 486 NIHNQNP---EELCTSPTLMTSQVASEP 510 P + T+P T+ V P Sbjct: 3034 VTPTPTPTGTQTPTTTPITTTTTVTPTP 3061 Score = 45.8 bits (107), Expect = 1e-04 Identities = 59/268 (22%), Positives = 95/268 (35%), Gaps = 48/268 (17%) Query: 265 PVRTATVSSPLTSPTSPSTLSLKSESESVSATEDLAPDAAQGEDNSEIKELLEEEEIEKE 324 P+ T T +P +PT T + + + + T P Q + I Sbjct: 2889 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI------------ 2936 Query: 325 GSEASSSEEDEPLPACNGPAQAQPSPTTERAKSQEEVLPSSTTPSPGGALSPSGQPSSSA 384 +++ P P G +PTT + V P TP+P G +P+ P ++ Sbjct: 2937 ----TTTTTVTPTPTPTGTQ----TPTTTPITTTTTVTP---TPTPTGTQTPTTTPITTT 2985 Query: 385 TEVVLRTRTASEGSEQPKKRASIQRTSAPPSRPPPPRA---TASPRPSSGNIPSSPTASG 441 T V T T + Q I T+ P P T +P ++ + +PT +G Sbjct: 2986 TTV---TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG 3042 Query: 442 GGSPTSPRASLGT---------GTASP-----RTSLEVSPNPEP--PEKPVRTPEAKENE 485 +PT+ + T GT +P T+ V+P P P + P TP Sbjct: 3043 TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 3102 Query: 486 NIHNQNP---EELCTSPTLMTSQVASEP 510 P + T+P T+ V P Sbjct: 3103 VTPTPTPTGTQTPTTTPITTTTTVTPTP 3130 Score = 45.8 bits (107), Expect = 1e-04 Identities = 59/268 (22%), Positives = 95/268 (35%), Gaps = 48/268 (17%) Query: 265 PVRTATVSSPLTSPTSPSTLSLKSESESVSATEDLAPDAAQGEDNSEIKELLEEEEIEKE 324 P+ T T +P +PT T + + + + T P Q + I Sbjct: 2958 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI------------ 3005 Query: 325 GSEASSSEEDEPLPACNGPAQAQPSPTTERAKSQEEVLPSSTTPSPGGALSPSGQPSSSA 384 +++ P P G +PTT + V P TP+P G +P+ P ++ Sbjct: 3006 ----TTTTTVTPTPTPTGTQ----TPTTTPITTTTTVTP---TPTPTGTQTPTTTPITTT 3054 Query: 385 TEVVLRTRTASEGSEQPKKRASIQRTSAPPSRPPPPRA---TASPRPSSGNIPSSPTASG 441 T V T T + Q I T+ P P T +P ++ + +PT +G Sbjct: 3055 TTV---TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG 3111 Query: 442 GGSPTSPRASLGT---------GTASP-----RTSLEVSPNPEP--PEKPVRTPEAKENE 485 +PT+ + T GT +P T+ V+P P P + P TP Sbjct: 3112 TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 3171 Query: 486 NIHNQNP---EELCTSPTLMTSQVASEP 510 P + T+P T+ V P Sbjct: 3172 VTPTPTPTGTQTPTTTPITTTTTVTPTP 3199 Score = 45.8 bits (107), Expect = 1e-04 Identities = 59/268 (22%), Positives = 95/268 (35%), Gaps = 48/268 (17%) Query: 265 PVRTATVSSPLTSPTSPSTLSLKSESESVSATEDLAPDAAQGEDNSEIKELLEEEEIEKE 324 P+ T T +P +PT T + + + + T P Q + I Sbjct: 3027 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI------------ 3074 Query: 325 GSEASSSEEDEPLPACNGPAQAQPSPTTERAKSQEEVLPSSTTPSPGGALSPSGQPSSSA 384 +++ P P G +PTT + V P TP+P G +P+ P ++ Sbjct: 3075 ----TTTTTVTPTPTPTGTQ----TPTTTPITTTTTVTP---TPTPTGTQTPTTTPITTT 3123 Query: 385 TEVVLRTRTASEGSEQPKKRASIQRTSAPPSRPPPPRA---TASPRPSSGNIPSSPTASG 441 T V T T + Q I T+ P P T +P ++ + +PT +G Sbjct: 3124 TTV---TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG 3180 Query: 442 GGSPTSPRASLGT---------GTASP-----RTSLEVSPNPEP--PEKPVRTPEAKENE 485 +PT+ + T GT +P T+ V+P P P + P TP Sbjct: 3181 TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 3240 Query: 486 NIHNQNP---EELCTSPTLMTSQVASEP 510 P + T+P T+ V P Sbjct: 3241 VTPTPTPTGTQTPTTTPITTTTTVTPTP 3268 Score = 45.8 bits (107), Expect = 1e-04 Identities = 59/268 (22%), Positives = 95/268 (35%), Gaps = 48/268 (17%) Query: 265 PVRTATVSSPLTSPTSPSTLSLKSESESVSATEDLAPDAAQGEDNSEIKELLEEEEIEKE 324 P+ T T +P +PT T + + + + T P Q + I Sbjct: 3096 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI------------ 3143 Query: 325 GSEASSSEEDEPLPACNGPAQAQPSPTTERAKSQEEVLPSSTTPSPGGALSPSGQPSSSA 384 +++ P P G +PTT + V P TP+P G +P+ P ++ Sbjct: 3144 ----TTTTTVTPTPTPTGTQ----TPTTTPITTTTTVTP---TPTPTGTQTPTTTPITTT 3192 Query: 385 TEVVLRTRTASEGSEQPKKRASIQRTSAPPSRPPPPRA---TASPRPSSGNIPSSPTASG 441 T V T T + Q I T+ P P T +P ++ + +PT +G Sbjct: 3193 TTV---TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG 3249 Query: 442 GGSPTSPRASLGT---------GTASP-----RTSLEVSPNPEP--PEKPVRTPEAKENE 485 +PT+ + T GT +P T+ V+P P P + P TP Sbjct: 3250 TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 3309 Query: 486 NIHNQNP---EELCTSPTLMTSQVASEP 510 P + T+P T+ V P Sbjct: 3310 VTPTPTPTGTQTPTTTPITTTTTVTPTP 3337 Score = 45.8 bits (107), Expect = 1e-04 Identities = 59/268 (22%), Positives = 95/268 (35%), Gaps = 48/268 (17%) Query: 265 PVRTATVSSPLTSPTSPSTLSLKSESESVSATEDLAPDAAQGEDNSEIKELLEEEEIEKE 324 P+ T T +P +PT T + + + + T P Q + I Sbjct: 3165 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI------------ 3212 Query: 325 GSEASSSEEDEPLPACNGPAQAQPSPTTERAKSQEEVLPSSTTPSPGGALSPSGQPSSSA 384 +++ P P G +PTT + V P TP+P G +P+ P ++ Sbjct: 3213 ----TTTTTVTPTPTPTGTQ----TPTTTPITTTTTVTP---TPTPTGTQTPTTTPITTT 3261 Query: 385 TEVVLRTRTASEGSEQPKKRASIQRTSAPPSRPPPPRA---TASPRPSSGNIPSSPTASG 441 T V T T + Q I T+ P P T +P ++ + +PT +G Sbjct: 3262 TTV---TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG 3318 Query: 442 GGSPTSPRASLGT---------GTASP-----RTSLEVSPNPEP--PEKPVRTPEAKENE 485 +PT+ + T GT +P T+ V+P P P + P TP Sbjct: 3319 TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 3378 Query: 486 NIHNQNP---EELCTSPTLMTSQVASEP 510 P + T+P T+ V P Sbjct: 3379 VTPTPTPTGTQTPTTTPITTTTTVTPTP 3406 Score = 45.8 bits (107), Expect = 1e-04 Identities = 59/268 (22%), Positives = 95/268 (35%), Gaps = 48/268 (17%) Query: 265 PVRTATVSSPLTSPTSPSTLSLKSESESVSATEDLAPDAAQGEDNSEIKELLEEEEIEKE 324 P+ T T +P +PT T + + + + T P Q + I Sbjct: 3234 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI------------ 3281 Query: 325 GSEASSSEEDEPLPACNGPAQAQPSPTTERAKSQEEVLPSSTTPSPGGALSPSGQPSSSA 384 +++ P P G +PTT + V P TP+P G +P+ P ++ Sbjct: 3282 ----TTTTTVTPTPTPTGTQ----TPTTTPITTTTTVTP---TPTPTGTQTPTTTPITTT 3330 Query: 385 TEVVLRTRTASEGSEQPKKRASIQRTSAPPSRPPPPRA---TASPRPSSGNIPSSPTASG 441 T V T T + Q I T+ P P T +P ++ + +PT +G Sbjct: 3331 TTV---TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG 3387 Query: 442 GGSPTSPRASLGT---------GTASP-----RTSLEVSPNPEP--PEKPVRTPEAKENE 485 +PT+ + T GT +P T+ V+P P P + P TP Sbjct: 3388 TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 3447 Query: 486 NIHNQNP---EELCTSPTLMTSQVASEP 510 P + T+P T+ V P Sbjct: 3448 VTPTPTPTGTQTPTTTPITTTTTVTPTP 3475 Score = 45.8 bits (107), Expect = 1e-04 Identities = 59/268 (22%), Positives = 95/268 (35%), Gaps = 48/268 (17%) Query: 265 PVRTATVSSPLTSPTSPSTLSLKSESESVSATEDLAPDAAQGEDNSEIKELLEEEEIEKE 324 P+ T T +P +PT T + + + + T P Q + I Sbjct: 3303 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI------------ 3350 Query: 325 GSEASSSEEDEPLPACNGPAQAQPSPTTERAKSQEEVLPSSTTPSPGGALSPSGQPSSSA 384 +++ P P G +PTT + V P TP+P G +P+ P ++ Sbjct: 3351 ----TTTTTVTPTPTPTGTQ----TPTTTPITTTTTVTP---TPTPTGTQTPTTTPITTT 3399 Query: 385 TEVVLRTRTASEGSEQPKKRASIQRTSAPPSRPPPPRA---TASPRPSSGNIPSSPTASG 441 T V T T + Q I T+ P P T +P ++ + +PT +G Sbjct: 3400 TTV---TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG 3456 Query: 442 GGSPTSPRASLGT---------GTASP-----RTSLEVSPNPEP--PEKPVRTPEAKENE 485 +PT+ + T GT +P T+ V+P P P + P TP Sbjct: 3457 TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 3516 Query: 486 NIHNQNP---EELCTSPTLMTSQVASEP 510 P + T+P T+ V P Sbjct: 3517 VTPTPTPTGTQTPTTTPITTTTTVTPTP 3544 Score = 45.8 bits (107), Expect = 1e-04 Identities = 59/268 (22%), Positives = 95/268 (35%), Gaps = 48/268 (17%) Query: 265 PVRTATVSSPLTSPTSPSTLSLKSESESVSATEDLAPDAAQGEDNSEIKELLEEEEIEKE 324 P+ T T +P +PT T + + + + T P Q + I Sbjct: 3372 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI------------ 3419 Query: 325 GSEASSSEEDEPLPACNGPAQAQPSPTTERAKSQEEVLPSSTTPSPGGALSPSGQPSSSA 384 +++ P P G +PTT + V P TP+P G +P+ P ++ Sbjct: 3420 ----TTTTTVTPTPTPTGTQ----TPTTTPITTTTTVTP---TPTPTGTQTPTTTPITTT 3468 Query: 385 TEVVLRTRTASEGSEQPKKRASIQRTSAPPSRPPPPRA---TASPRPSSGNIPSSPTASG 441 T V T T + Q I T+ P P T +P ++ + +PT +G Sbjct: 3469 TTV---TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG 3525 Query: 442 GGSPTSPRASLGT---------GTASP-----RTSLEVSPNPEP--PEKPVRTPEAKENE 485 +PT+ + T GT +P T+ V+P P P + P TP Sbjct: 3526 TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 3585 Query: 486 NIHNQNP---EELCTSPTLMTSQVASEP 510 P + T+P T+ V P Sbjct: 3586 VTPTPTPTGTQTPTTTPITTTTTVTPTP 3613 Score = 45.8 bits (107), Expect = 1e-04 Identities = 59/268 (22%), Positives = 95/268 (35%), Gaps = 48/268 (17%) Query: 265 PVRTATVSSPLTSPTSPSTLSLKSESESVSATEDLAPDAAQGEDNSEIKELLEEEEIEKE 324 P+ T T +P +PT T + + + + T P Q + I Sbjct: 3441 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI------------ 3488 Query: 325 GSEASSSEEDEPLPACNGPAQAQPSPTTERAKSQEEVLPSSTTPSPGGALSPSGQPSSSA 384 +++ P P G +PTT + V P TP+P G +P+ P ++ Sbjct: 3489 ----TTTTTVTPTPTPTGTQ----TPTTTPITTTTTVTP---TPTPTGTQTPTTTPITTT 3537 Query: 385 TEVVLRTRTASEGSEQPKKRASIQRTSAPPSRPPPPRA---TASPRPSSGNIPSSPTASG 441 T V T T + Q I T+ P P T +P ++ + +PT +G Sbjct: 3538 TTV---TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG 3594 Query: 442 GGSPTSPRASLGT---------GTASP-----RTSLEVSPNPEP--PEKPVRTPEAKENE 485 +PT+ + T GT +P T+ V+P P P + P TP Sbjct: 3595 TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 3654 Query: 486 NIHNQNP---EELCTSPTLMTSQVASEP 510 P + T+P T+ V P Sbjct: 3655 VTPTPTPTGTQTPTTTPITTTTTVTPTP 3682 Score = 45.8 bits (107), Expect = 1e-04 Identities = 59/268 (22%), Positives = 95/268 (35%), Gaps = 48/268 (17%) Query: 265 PVRTATVSSPLTSPTSPSTLSLKSESESVSATEDLAPDAAQGEDNSEIKELLEEEEIEKE 324 P+ T T +P +PT T + + + + T P Q + I Sbjct: 3510 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI------------ 3557 Query: 325 GSEASSSEEDEPLPACNGPAQAQPSPTTERAKSQEEVLPSSTTPSPGGALSPSGQPSSSA 384 +++ P P G +PTT + V P TP+P G +P+ P ++ Sbjct: 3558 ----TTTTTVTPTPTPTGTQ----TPTTTPITTTTTVTP---TPTPTGTQTPTTTPITTT 3606 Query: 385 TEVVLRTRTASEGSEQPKKRASIQRTSAPPSRPPPPRA---TASPRPSSGNIPSSPTASG 441 T V T T + Q I T+ P P T +P ++ + +PT +G Sbjct: 3607 TTV---TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG 3663 Query: 442 GGSPTSPRASLGT---------GTASP-----RTSLEVSPNPEP--PEKPVRTPEAKENE 485 +PT+ + T GT +P T+ V+P P P + P TP Sbjct: 3664 TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 3723 Query: 486 NIHNQNP---EELCTSPTLMTSQVASEP 510 P + T+P T+ V P Sbjct: 3724 VTPTPTPTGTQTPTTTPITTTTTVTPTP 3751 Score = 45.8 bits (107), Expect = 1e-04 Identities = 59/268 (22%), Positives = 95/268 (35%), Gaps = 48/268 (17%) Query: 265 PVRTATVSSPLTSPTSPSTLSLKSESESVSATEDLAPDAAQGEDNSEIKELLEEEEIEKE 324 P+ T T +P +PT T + + + + T P Q + I Sbjct: 3579 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI------------ 3626 Query: 325 GSEASSSEEDEPLPACNGPAQAQPSPTTERAKSQEEVLPSSTTPSPGGALSPSGQPSSSA 384 +++ P P G +PTT + V P TP+P G +P+ P ++ Sbjct: 3627 ----TTTTTVTPTPTPTGTQ----TPTTTPITTTTTVTP---TPTPTGTQTPTTTPITTT 3675 Query: 385 TEVVLRTRTASEGSEQPKKRASIQRTSAPPSRPPPPRA---TASPRPSSGNIPSSPTASG 441 T V T T + Q I T+ P P T +P ++ + +PT +G Sbjct: 3676 TTV---TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG 3732 Query: 442 GGSPTSPRASLGT---------GTASP-----RTSLEVSPNPEP--PEKPVRTPEAKENE 485 +PT+ + T GT +P T+ V+P P P + P TP Sbjct: 3733 TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 3792 Query: 486 NIHNQNP---EELCTSPTLMTSQVASEP 510 P + T+P T+ V P Sbjct: 3793 VTPTPTPTGTQTPTTTPITTTTTVTPTP 3820 Score = 45.8 bits (107), Expect = 1e-04 Identities = 59/268 (22%), Positives = 95/268 (35%), Gaps = 48/268 (17%) Query: 265 PVRTATVSSPLTSPTSPSTLSLKSESESVSATEDLAPDAAQGEDNSEIKELLEEEEIEKE 324 P+ T T +P +PT T + + + + T P Q + I Sbjct: 3648 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI------------ 3695 Query: 325 GSEASSSEEDEPLPACNGPAQAQPSPTTERAKSQEEVLPSSTTPSPGGALSPSGQPSSSA 384 +++ P P G +PTT + V P TP+P G +P+ P ++ Sbjct: 3696 ----TTTTTVTPTPTPTGTQ----TPTTTPITTTTTVTP---TPTPTGTQTPTTTPITTT 3744 Query: 385 TEVVLRTRTASEGSEQPKKRASIQRTSAPPSRPPPPRA---TASPRPSSGNIPSSPTASG 441 T V T T + Q I T+ P P T +P ++ + +PT +G Sbjct: 3745 TTV---TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG 3801 Query: 442 GGSPTSPRASLGT---------GTASP-----RTSLEVSPNPEP--PEKPVRTPEAKENE 485 +PT+ + T GT +P T+ V+P P P + P TP Sbjct: 3802 TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 3861 Query: 486 NIHNQNP---EELCTSPTLMTSQVASEP 510 P + T+P T+ V P Sbjct: 3862 VTPTPTPTGTQTPTTTPITTTTTVTPTP 3889 Score = 45.8 bits (107), Expect = 1e-04 Identities = 59/268 (22%), Positives = 95/268 (35%), Gaps = 48/268 (17%) Query: 265 PVRTATVSSPLTSPTSPSTLSLKSESESVSATEDLAPDAAQGEDNSEIKELLEEEEIEKE 324 P+ T T +P +PT T + + + + T P Q + I Sbjct: 3717 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI------------ 3764 Query: 325 GSEASSSEEDEPLPACNGPAQAQPSPTTERAKSQEEVLPSSTTPSPGGALSPSGQPSSSA 384 +++ P P G +PTT + V P TP+P G +P+ P ++ Sbjct: 3765 ----TTTTTVTPTPTPTGTQ----TPTTTPITTTTTVTP---TPTPTGTQTPTTTPITTT 3813 Query: 385 TEVVLRTRTASEGSEQPKKRASIQRTSAPPSRPPPPRA---TASPRPSSGNIPSSPTASG 441 T V T T + Q I T+ P P T +P ++ + +PT +G Sbjct: 3814 TTV---TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG 3870 Query: 442 GGSPTSPRASLGT---------GTASP-----RTSLEVSPNPEP--PEKPVRTPEAKENE 485 +PT+ + T GT +P T+ V+P P P + P TP Sbjct: 3871 TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 3930 Query: 486 NIHNQNP---EELCTSPTLMTSQVASEP 510 P + T+P T+ V P Sbjct: 3931 VTPTPTPTGTQTPTTTPITTTTTVTPTP 3958 Score = 45.8 bits (107), Expect = 1e-04 Identities = 59/268 (22%), Positives = 95/268 (35%), Gaps = 48/268 (17%) Query: 265 PVRTATVSSPLTSPTSPSTLSLKSESESVSATEDLAPDAAQGEDNSEIKELLEEEEIEKE 324 P+ T T +P +PT T + + + + T P Q + I Sbjct: 3786 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI------------ 3833 Query: 325 GSEASSSEEDEPLPACNGPAQAQPSPTTERAKSQEEVLPSSTTPSPGGALSPSGQPSSSA 384 +++ P P G +PTT + V P TP+P G +P+ P ++ Sbjct: 3834 ----TTTTTVTPTPTPTGTQ----TPTTTPITTTTTVTP---TPTPTGTQTPTTTPITTT 3882 Query: 385 TEVVLRTRTASEGSEQPKKRASIQRTSAPPSRPPPPRA---TASPRPSSGNIPSSPTASG 441 T V T T + Q I T+ P P T +P ++ + +PT +G Sbjct: 3883 TTV---TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG 3939 Query: 442 GGSPTSPRASLGT---------GTASP-----RTSLEVSPNPEP--PEKPVRTPEAKENE 485 +PT+ + T GT +P T+ V+P P P + P TP Sbjct: 3940 TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 3999 Query: 486 NIHNQNP---EELCTSPTLMTSQVASEP 510 P + T+P T+ V P Sbjct: 4000 VTPTPTPTGTQTPTTTPITTTTTVTPTP 4027 Score = 45.8 bits (107), Expect = 1e-04 Identities = 59/268 (22%), Positives = 95/268 (35%), Gaps = 48/268 (17%) Query: 265 PVRTATVSSPLTSPTSPSTLSLKSESESVSATEDLAPDAAQGEDNSEIKELLEEEEIEKE 324 P+ T T +P +PT T + + + + T P Q + I Sbjct: 3855 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI------------ 3902 Query: 325 GSEASSSEEDEPLPACNGPAQAQPSPTTERAKSQEEVLPSSTTPSPGGALSPSGQPSSSA 384 +++ P P G +PTT + V P TP+P G +P+ P ++ Sbjct: 3903 ----TTTTTVTPTPTPTGTQ----TPTTTPITTTTTVTP---TPTPTGTQTPTTTPITTT 3951 Query: 385 TEVVLRTRTASEGSEQPKKRASIQRTSAPPSRPPPPRA---TASPRPSSGNIPSSPTASG 441 T V T T + Q I T+ P P T +P ++ + +PT +G Sbjct: 3952 TTV---TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG 4008 Query: 442 GGSPTSPRASLGT---------GTASP-----RTSLEVSPNPEP--PEKPVRTPEAKENE 485 +PT+ + T GT +P T+ V+P P P + P TP Sbjct: 4009 TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 4068 Query: 486 NIHNQNP---EELCTSPTLMTSQVASEP 510 P + T+P T+ V P Sbjct: 4069 VTPTPTPTGTQTPTTTPITTTTTVTPTP 4096 Score = 44.7 bits (104), Expect = 2e-04 Identities = 50/231 (21%), Positives = 82/231 (35%), Gaps = 41/231 (17%) Query: 265 PVRTATVSSPLTSPTSPSTLSLKSESESVSATEDLAPDAAQGEDNSEIKELLEEEEIEKE 324 P+ T T +P +PT T + + + + T P Q + I Sbjct: 4108 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI------------ 4155 Query: 325 GSEASSSEEDEPLPACNGPAQAQPSPTTERAKSQEEVLPSSTTPSPGGALSPSGQPSSSA 384 +++ P P G +PTT + V P TP+P G + +G P+ ++ Sbjct: 4156 ----TTTTTVTPTPTPTGTQ----TPTTTPITTTTTVTP---TPTPTG--TQTGPPTHTS 4202 Query: 385 TEVVLRTRTA-----------SEGSEQPKKRASIQRTSAPP-----SRPPPPRATASPRP 428 T + T+ S + P ++ ++ PP S PP TA Sbjct: 4203 TAPIAELTTSNPPPESSTPQTSRSTSSPLTESTTLLSTLPPAIEMTSTAPPSTPTAPTTT 4262 Query: 429 SSGNIPSSPTASGGGSPTSPRASLGTGTASPRTSLEVSPNPEPPEKPVRTP 479 S G+ S P ++ P +P TG++S T V P TP Sbjct: 4263 SGGHTLSPPPSTTTSPPGTPTRGTTTGSSSAPTPSTVQTTTTSAWTPTPTP 4313 Score = 41.2 bits (95), Expect = 0.003 Identities = 44/188 (23%), Positives = 73/188 (38%), Gaps = 28/188 (14%) Query: 348 PSPTTERAKSQEEVLPSST---TPSPGGALSPSGQPSSSATEVVLRTRTASEGSEQPKKR 404 P+PT + + + ++T TP+P G +P+ P ++ T V T T + Q Sbjct: 1911 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV---TPTPTPTGTQTPTT 1967 Query: 405 ASIQRTSAPPSRPPPPRA---TASPRPSSGNIPSSPTASGGGSPTSPRASLGT------- 454 I T+ P P T +P ++ + +PT +G +PT+ + T Sbjct: 1968 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2027 Query: 455 --GTASP-----RTSLEVSPNPEP--PEKPVRTPEAKENENIHNQNP---EELCTSPTLM 502 GT +P T+ V+P P P + P TP P + T+P Sbjct: 2028 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 2087 Query: 503 TSQVASEP 510 T+ V P Sbjct: 2088 TTTVTPTP 2095 Score = 31.2 bits (69), Expect = 2.6 Identities = 42/171 (24%), Positives = 62/171 (36%), Gaps = 36/171 (21%) Query: 350 PTTERAKSQEEVLPSSTTPSPGGALSPSGQPSSSATEVVLRTRTASEGSEQPKKRASIQR 409 PTT + E P +TTP + T V T T + G++ P Sbjct: 1882 PTTMTTTTTENPTPPTTTPI-------------TTTTTVTPTPTPT-GTQTPTTTPITTT 1927 Query: 410 TSAPPSRPPPPRATASPRPSSGNIPSSPTASGGGSPTSPRASLGTGTASP-----RTSLE 464 T+ P+ P P T +P + P + T + +PT TGT +P T+ Sbjct: 1928 TTVTPT--PTPTGTQTPTTT----PITTTTTVTPTPTP------TGTQTPTTTPITTTTT 1975 Query: 465 VSPNPEP--PEKPVRTPEAKENENIHNQNP---EELCTSPTLMTSQVASEP 510 V+P P P + P TP P + T+P T+ V P Sbjct: 1976 VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 2026 >gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens] Length = 1020 Score = 59.7 bits (143), Expect = 7e-09 Identities = 93/402 (23%), Positives = 151/402 (37%), Gaps = 49/402 (12%) Query: 147 VDYDSARHHLEAVQNAKKKDEAKTAKAEEEFNKAQTVFEDLNQELLEELPILYNSRIGCY 206 V+ D+ R E + +++ +A+T + E A +D + EL + + I Y Sbjct: 306 VNTDAMRSAQEEITEYRRQLQARTTELE-----ALKSTKDSLERQRSELEDRHQADIASY 360 Query: 207 VTIFQNISNLRDVFYREMSKLNHNLYEVMSKL-EKQHSNKVFVVKGLSSSSRRSLVISPP 265 Q + ++L + +E+ ++L E Q V + + ++ R L+ Sbjct: 361 QEAIQQLD----------AELRNTKWEMAAQLREYQDLLNVKMALDIEIAAYRKLLEGEE 410 Query: 266 VRTATVSSPLTSPTS----PST---LSLKSESESVSATEDLAPDAA----QGEDNSEIKE 314 R P + P PS + +KSE E + E + Q E+ +E Sbjct: 411 CRIGFGPIPFSLPEGLPKIPSVSTHIKVKSE-EKIKVVEKSEKETVIVEEQTEETQVTEE 469 Query: 315 LLEEEEIE---KEGSEASSSEEDEPLPACNGPAQAQPSPTTERAKSQEEVLPS---STTP 368 + EEEE E +EG E EE+E G + SP E A S E+ S Sbjct: 470 VTEEEEKEAKEEEGKEEEGGEEEE----AEGGEEETKSPPAEEAASPEKEAKSPVKEEAK 525 Query: 369 SPGGALSPSGQPSSSATEVVLRTRTASEGSEQ----PKKRASIQRTSAPPSRPPPPRATA 424 SP A SP + + S EV + S E+ P+ ++ + + P+ P Sbjct: 526 SPAEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPPEAKSPEKEEAKSPAEVKSPEKAK 585 Query: 425 SPRPSSGNIPS-SPTASGGGSPTSPRASLGTGTASPRTSLEVSP----NPEPPEKPVRTP 479 SP P+ + + SP A SP SP +PE + P + Sbjct: 586 SPAKEEAKSPAEAKSPEKAKSPVKEEAKSPAEAKSPVKEEAKSPAEVKSPEKAKSPTK-E 644 Query: 480 EAKENENIHNQNPEELCTSPTLMTSQVASEPGEAKKMEDKEK 521 EAK E + EE SP S V +E +K + K Sbjct: 645 EAKSPEKAKSPEKEE-AKSPEKAKSPVKAEAKSPEKAKSPVK 685 Score = 54.3 bits (129), Expect = 3e-07 Identities = 59/264 (22%), Positives = 104/264 (39%), Gaps = 22/264 (8%) Query: 277 SPTSPSTLSLKSESESVSATEDLAPDAAQGEDNSEIKELLEEEEIEKEGSEASSSEEDEP 336 SP + S + E++S E +P A+ + E K E + EK +++ + EE + Sbjct: 503 SPPAEEAASPEKEAKSPVKEEAKSPAEAKSPEKEEAKSPAEVKSPEK--AKSPAKEEAKS 560 Query: 337 LPACNGPAQAQ-------PSPTTERAKSQEEVLPSSTTPSPGGALSP----SGQPSSSAT 385 P P + + SP ++ ++EE + SP A SP + P+ + + Sbjct: 561 PPEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPAEAKSPEKAKSPVKEEAKSPAEAKS 620 Query: 386 EVVLRTRTASEGSEQPKKRASIQRTSAPPSRPPPPRATASPRPSSGNIPSSPTASGGGSP 445 V ++ +E K ++ + + P + P + P SP + SP Sbjct: 621 PVKEEAKSPAEVKSPEKAKSPTKEEAKSPEKAKSPEKEEAKSPEKA---KSPVKAEAKSP 677 Query: 446 TSPRASLGTGTASPRTS----LEVSPNPEPPEKPVRTPEAKENENIHNQNPEELCTSPTL 501 ++ + SP + E + +PE + PV+ EAK E + EE T P Sbjct: 678 EKAKSPVKAEAKSPEKAKSPVKEEAKSPEKAKSPVK-EEAKSPEKAKSPVKEEAKT-PEK 735 Query: 502 MTSQVASEPGEAKKMEDKEKDNKL 525 S V E +K + EK L Sbjct: 736 AKSPVKEEAKSPEKAKSPEKAKTL 759 Score = 53.1 bits (126), Expect = 7e-07 Identities = 69/266 (25%), Positives = 100/266 (37%), Gaps = 31/266 (11%) Query: 283 TLSLKSESESVSATEDLAPDAAQGEDNSEIKELLEEEEIEKEGSE----------ASSSE 332 T+ ++ ++E TE++ + + E KE EE E EG E A+S E Sbjct: 454 TVIVEEQTEETQVTEEVTEEEEKEAKEEEGKEEEGGEEEEAEGGEEETKSPPAEEAASPE 513 Query: 333 EDEPLPA---CNGPAQAQPSPTTERAKSQEEVLPSSTTPSPGG--------ALSPSGQPS 381 ++ P PA+A+ SP E AKS EV SP A SP + + Sbjct: 514 KEAKSPVKEEAKSPAEAK-SPEKEEAKSPAEVKSPEKAKSPAKEEAKSPPEAKSPEKEEA 572 Query: 382 SSATEVVLRTRTASEGSEQPKKRA---SIQRTSAP-PSRPPPPRATASPRPSSGNIPSS- 436 S EV + S E+ K A S ++ +P P SP P+ Sbjct: 573 KSPAEVKSPEKAKSPAKEEAKSPAEAKSPEKAKSPVKEEAKSPAEAKSPVKEEAKSPAEV 632 Query: 437 PTASGGGSPTSPRASLGTGTASPRTSLEVSPNPEPPEKPVRTPEAKENENIHNQNPEELC 496 + SPT A SP E + +PE + PV+ EAK E + E Sbjct: 633 KSPEKAKSPTKEEAKSPEKAKSPEK--EEAKSPEKAKSPVKA-EAKSPEKAKSPVKAE-A 688 Query: 497 TSPTLMTSQVASEPGEAKKMEDKEKD 522 SP S V E +K + K+ Sbjct: 689 KSPEKAKSPVKEEAKSPEKAKSPVKE 714 Score = 44.7 bits (104), Expect = 2e-04 Identities = 60/283 (21%), Positives = 100/283 (35%), Gaps = 19/283 (6%) Query: 250 KGLSSSSRRSLVISPPVRTATVSSPLTSPTSPSTLSLKSESESVSATEDLAPDAAQGEDN 309 K S ++L + P SP KS + + + A + + Sbjct: 749 KAKSPEKAKTLDVKSPEAKTPAKEEARSPADKFPEKAKSPVKEEVKSPEKAKSPLKEDAK 808 Query: 310 SEIKELLEEEEIEKEGSEASSSEE----DEPLPACNGPAQAQPSPTTERAKSQEEVLPSS 365 + KE+ ++EE++ E +E + P A A A P T E+ S++E P Sbjct: 809 APEKEIPKKEEVKSPVKEEEKPQEVKVKEPPKKAEEEKAPATPK-TEEKKDSKKEEAPKK 867 Query: 366 TTPSPGGALSPSGQPSSSATEVVLRTRTASEGSE-QPKKRASIQRTSAPPSRPPPPRATA 424 P P + A E ++ ++ E + KK+ AP + A Sbjct: 868 EAPKP-----KVEEKKEPAVEKPKESKVEAKKEEAEDKKKVPTPEKEAPAK--VEVKEDA 920 Query: 425 SPRPSSGNIPSSPTASGGGSPTSPRASLGTGTASPRTSLEVSPNPEPPEKPVRTPEAKEN 484 P+ + P + P+ P T E + PE EKP +AKE+ Sbjct: 921 KPKEKTEVAKKEPDDAKAKEPSKPAEKKEAAPEKKDTKEEKAKKPE--EKPKTEAKAKED 978 Query: 485 ENIHNQNPEE---LCTSPTLMTSQVASEPGEAKKMEDKEKDNK 524 + ++ P + + T Q S+P E K EDK K Sbjct: 979 DKTLSKEPSKPKAEKAEKSSSTDQKDSKPPE-KATEDKAAKGK 1020 Score = 44.3 bits (103), Expect = 3e-04 Identities = 65/317 (20%), Positives = 116/317 (36%), Gaps = 27/317 (8%) Query: 263 SPPVRTATVSSPLTSPT---SPSTLSLKSESESVSATEDLA--PDAAQGEDNSEIKELLE 317 SP + V + SP SP KS ++ S ++ A P+ A+ E K Sbjct: 662 SPEKAKSPVKAEAKSPEKAKSPVKAEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKS--- 718 Query: 318 EEEIEKEGSEASSSEEDEPLPACNGPAQAQPSPTTERAKSQEEVLPSSTTPSPGGALSPS 377 E+ + E + + E P + + + E+AK+ + P + TP+ A SP+ Sbjct: 719 PEKAKSPVKEEAKTPEKAKSPVKEEAKSPEKAKSPEKAKTLDVKSPEAKTPAKEEARSPA 778 Query: 378 GQPSSSATEVVLRTRTASEGSEQPKKRASIQRTSAPPSRPPPPRATASP-----RPSSGN 432 + A V + E ++ P K + AP P SP +P Sbjct: 779 DKFPEKAKSPVKEEVKSPEKAKSPLK----EDAKAPEKEIPKKEEVKSPVKEEEKPQEVK 834 Query: 433 IPSSP-TASGGGSPTSPRASLGTGTASPRTSLEVSPNPEPPEK---PVRTP-----EAKE 483 + P A +P +P+ + + +P P+ EK V P EAK+ Sbjct: 835 VKEPPKKAEEEKAPATPKTEEKKDSKKEEAPKKEAPKPKVEEKKEPAVEKPKESKVEAKK 894 Query: 484 NENIHNQN-PEELCTSPTLMTSQVASEPGEAKKMEDKEKDNKLISANSSEGQDQLQVSMV 542 E + P +P + + ++P E ++ KE D+ S + + Sbjct: 895 EEAEDKKKVPTPEKEAPAKVEVKEDAKPKEKTEVAKKEPDDAKAKEPSKPAEKKEAAPEK 954 Query: 543 PENNNLTAPEPQEEVST 559 + A +P+E+ T Sbjct: 955 KDTKEEKAKKPEEKPKT 971 >gi|117414137 retinitis pigmentosa 1-like 1 [Homo sapiens] Length = 2400 Score = 58.9 bits (141), Expect = 1e-08 Identities = 74/288 (25%), Positives = 107/288 (37%), Gaps = 33/288 (11%) Query: 289 ESESVSATEDLAPDAAQGEDNSEIKELLEEEEIEKEGSEASSSE-----EDEPLPACNGP 343 ESE V A E A AQ + E E E + E EG EA +E E E + A + Sbjct: 2097 ESEGVEAPE--AEGEAQKAEGIEAPETEGEAQPESEGIEAPEAEGEAQPESEGVEAQDAE 2154 Query: 344 AQAQPSPTTERAKSQEEVLPSSTTPSPGGALSPSGQPSSSATEVVLRTRTASEGSEQPKK 403 +AQP A+ EE QP S E +EG QP+ Sbjct: 2155 GEAQPESEGIEAQEAEEEAQPELEGVEAPEAEGEAQPESEGIEA-----PEAEGEAQPEL 2209 Query: 404 RASIQRTSAPPSRPPPPRATASPRPSSGNIPSSPTASGGGSPTSPRASLGTGTASPRTSL 463 ++ A P P +P P S + G SP+ SLG G + + Sbjct: 2210 EG-VEAPEAEEEAQPEPEGVETPEAEGEAQPESEGETQGEKKGSPQVSLGDGQSEEASE- 2267 Query: 464 EVSPNPEPPEKPVRTPEAKENENIHNQNPEELCTSPTLMTSQVASEPGEAKKMEDKEKDN 523 S +P P ++P TP + +Q P S T +S AS G + +D E D+ Sbjct: 2268 --SSSPVPEDRP--TPPPSPGGDTPHQRP----GSQTGPSSSRASSWGNCWQ-KDSENDH 2318 Query: 524 KLISANSSEGQ-------DQLQVSMVPENNNLTAPEPQEEVSTSENPQ 564 L S + + ++ M PE+ + E +E S P+ Sbjct: 2319 VLGDTRSPDAKSTGTPHAERKATRMYPES---STSEQEEAPLGSRTPE 2363 Score = 47.4 bits (111), Expect = 4e-05 Identities = 54/219 (24%), Positives = 82/219 (37%), Gaps = 32/219 (14%) Query: 289 ESESVSATEDLAPDAAQGEDNSEIKELL-----EEEEIEKEGSEASSSEEDEPLPACNGP 343 ES+ V A E A + AQ E E++E E E+++ + +E + E E + A Sbjct: 2051 ESDGVEAPE--AEEEAQ-EAEGEVQEAEGEAHPESEDVDAQEAEGEAQPESEGVEAPEAE 2107 Query: 344 AQAQPSPTTERAKSQEEVLPSS---TTPSPGGALSPSGQPSSSATEVVLRTRTASEGSEQ 400 +AQ + E +++ E P S P G QP S E +EG Q Sbjct: 2108 GEAQKAEGIEAPETEGEAQPESEGIEAPEAEG----EAQPESEGVEA-----QDAEGEAQ 2158 Query: 401 PKKRASIQRTSAPPSRP-----PPPRATASPRPSSGNIPSSPTASGGGSPTSPRASLGTG 455 P+ + + ++P P A +P S I +P A G P G Sbjct: 2159 PESEGIEAQEAEEEAQPELEGVEAPEAEGEAQPESEGI-EAPEAEGEAQPEL------EG 2211 Query: 456 TASPRTSLEVSPNPEPPEKPVRTPEAKENENIHNQNPEE 494 +P E P PE E P EA+ Q ++ Sbjct: 2212 VEAPEAEEEAQPEPEGVETPEAEGEAQPESEGETQGEKK 2250 Score = 44.7 bits (104), Expect = 2e-04 Identities = 69/314 (21%), Positives = 116/314 (36%), Gaps = 56/314 (17%) Query: 287 KSESESVSATEDL-APDAAQGEDNSEIKELLEEEEIEKEGSEASSSEEDEPLPACNGPAQ 345 ++E E+ +E + AP+A +E + E E++E +E + E E + + Sbjct: 1839 EAEGEAQPESEGVEAPEAEGDAQEAEGEAQPESEDVEAPEAEGEAQPESEDVETPEAEWE 1898 Query: 346 AQP-SPTTERAKSQEEVLPSSTT-----------PSPGGA-------------------- 373 QP S E ++++E P + + P GA Sbjct: 1899 VQPESEGAEAPEAEKEAQPETESVEALETEGEDEPESEGAEAQEAEEAAQEAEGQTQPES 1958 Query: 374 -------LSPSGQPSS---SATEVVLRTRTASEGSEQPKKRASIQRTSAPPSRPPPPRAT 423 QP S A EV + T+ A EG QP+ + AP + A Sbjct: 1959 EVIESQEAEEEAQPESEDVEALEVEVETQEA-EGEAQPES----EDVEAPEAEGEMQEAE 2013 Query: 424 ASPRPSSGNIPSSPTASGGGSPTSPRASLGT-GTASPRTSLEVSPNPEPPEKPVRTPEAK 482 +P S + + P + G + + T G A P + +P E E E + Sbjct: 2014 EEAQPESDGVEAQPKSEGEEAQEVEGETQKTEGDAQPESDGVEAPEAE-EEAQEAEGEVQ 2072 Query: 483 ENENIHNQNPEELCTSPTLMTSQVASEPGEAKKMEDKEKDNKLISANSSEGQDQLQVSMV 542 E E + E++ +Q SE EA + E + + + I A +EG+ Q Sbjct: 2073 EAEGEAHPESEDVDAQEAEGEAQPESEGVEAPEAEGEAQKAEGIEAPETEGEAQ------ 2126 Query: 543 PENNNLTAPEPQEE 556 PE+ + APE + E Sbjct: 2127 PESEGIEAPEAEGE 2140 Score = 42.0 bits (97), Expect = 0.001 Identities = 76/359 (21%), Positives = 124/359 (34%), Gaps = 48/359 (13%) Query: 240 KQHSNKVFVVKGLSSSSRRSLVISPPVRTATVSSPLTSPTSPSTLSLKSESESVSATE-- 297 +Q +++ ++ LS+ S R+L + P T P S S L ++E E E Sbjct: 1604 QQRRHRLRGLRNLSAFSERTLGLGPLSFTLE-DEPALSTALGSQLGEEAEGEEFCPCEAC 1662 Query: 298 ------DLAPDAAQGEDNSEIKELLEEEEI-EKEGSEASSSEEDEPLPACNGPAQAQPSP 350 ++P A G IKE + ++I +++ E + E E P G P+ Sbjct: 1663 VRKKVSPMSPKATMGATRGPIKEAFDLQQILQRKRGEHTDGEAAEVAP---GKTHTDPT- 1718 Query: 351 TTERAKSQEEVLPSSTTPSPGGALSPSGQPSSSATEVVLRTRTASEGSEQPKKRASIQRT 410 +T + E L + PG G+ S +EG ++R Sbjct: 1719 STRTVQGAEGGLGPGLSQGPGVDEGEDGEGSQRLNRDKDPKLGEAEGDAMAQEREGKTHN 1778 Query: 411 SAPPSRPPPPRATA-----SPRPSSGNIPSSPT------ASGGGSPTSPRASLGTGTASP 459 S + A S R +G S A+ GG ++ G +P Sbjct: 1779 SETSAGSELGEAEQEGEGISERGETGGQGSGHEDNLQGEAAAGGDQDPGQSDGAEGIEAP 1838 Query: 460 RTSLEVSPNPEPPEKP----------------VRTPEAKENENIHNQNPEELCTSPTLMT 503 E P E E P EA E E E++ T Sbjct: 1839 EAEGEAQPESEGVEAPEAEGDAQEAEGEAQPESEDVEAPEAEGEAQPESEDVETPEAEWE 1898 Query: 504 SQVASEPGEAKKME-DKEKDNKLISANSSEGQDQLQVSMVPENNNLTAPEPQEEVSTSE 561 Q SE EA + E + + + + + A +EG+D+ PE+ A E +E +E Sbjct: 1899 VQPESEGAEAPEAEKEAQPETESVEALETEGEDE------PESEGAEAQEAEEAAQEAE 1951 Score = 39.3 bits (90), Expect = 0.010 Identities = 67/264 (25%), Positives = 101/264 (38%), Gaps = 35/264 (13%) Query: 259 SLVISPPVRTATVSSPLTSPTSPSTLSLKSESESVSATEDLAPDAAQGEDNSEIKELLEE 318 S ++P V + VS ++ +PS + + P + S L EE Sbjct: 737 SATVTPAVHSDFVSG-VSPHNAPSAGWAGDAGSRTCSPAPIPPHTSDSCSKSGAASLGEE 795 Query: 319 EEIEKEGSEASSSEEDEPLPACNGPAQA--------QPSPTTERAKSQEEV-LPSSTTPS 369 + S + P GP ++ QP+ +R S E L P+ Sbjct: 796 ARDTPQPSSPLVLQVGRPEQGAVGPHRSHCCSQPGTQPAQEAQRGPSPEASWLCGRYCPT 855 Query: 370 PGGALSPSGQPSSSATEVVLRTRTASEGSEQPKKRASIQRTSAPP---SRPPPPRATASP 426 P P G+P + R++S GS +++ + P +R P P T SP Sbjct: 856 P-----PRGRPCP-------QRRSSSCGSTGSSHQSTARGPGGSPQEGTRQPGP--TPSP 901 Query: 427 RPSSGNIPSSPTASGGGS-PTSPRASLGTGTASPRTSLEVSPNPEPPEKPVRTPEAKENE 485 P+SG S + G GS S +L +G P+ E S P P +PEA E Sbjct: 902 GPNSGASRRSSASQGAGSRGLSEEKTLRSG-GGPQGQEEAS-GVSPSSLPRSSPEAVVRE 959 Query: 486 NIHNQNPEELCTSPTLMTSQVASE 509 + N PEE P LMT ++A E Sbjct: 960 WLDN-IPEE----PILMTYELADE 978 Score = 33.9 bits (76), Expect = 0.41 Identities = 40/148 (27%), Positives = 65/148 (43%), Gaps = 25/148 (16%) Query: 286 LKSESESVSATEDLAPDAAQGEDNSEIKELLEEEEIEKEG-------SEASS-----SEE 333 L+ E + ++ QGE ++E L+EE + +EG SEASS S+E Sbjct: 1367 LQEEGVQLEEVKEGPEGGLQGE---ALEEGLKEEGLPEEGSVHGQELSEASSPDGKGSQE 1423 Query: 334 DEPL---PACNGPAQAQPSPT------TERAKSQEEVLPSSTTPSPGGALSPSGQPSSSA 384 D+P+ A A A+P P TE E PS++ G L P + A Sbjct: 1424 DDPVQEEEAGRASASAEPCPAEGTEEPTEPPSHLSETDPSASERQSGSQLEPGLEKPPGA 1483 Query: 385 TEVVLRTRTASEGSEQPKKRASIQRTSA 412 T ++ + T ++ ++ +R+S SA Sbjct: 1484 T-MMGQEHTQAQPTQGAAERSSSVACSA 1510 Score = 30.8 bits (68), Expect = 3.5 Identities = 36/152 (23%), Positives = 51/152 (33%), Gaps = 10/152 (6%) Query: 291 ESVSATEDLAPDAAQGEDNSEIK------ELLEEEEIEKEGSEASSSEEDEPLPACNGPA 344 E E L + Q E+ E + E + EEIE+ G E E + GP Sbjct: 1323 EETKTEEGLQEEGVQLEETKETEGEGQQEEEAQLEEIEETGGEGLQEEGVQLEEVKEGPE 1382 Query: 345 QAQPSPTTERAKSQEEVLPSSTT---PSPGGALSPSGQPSSSATEVVLRTRTASEGSEQP 401 E +EE LP + A SP G+ S V + S +P Sbjct: 1383 GGLQGEALEEGL-KEEGLPEEGSVHGQELSEASSPDGKGSQEDDPVQEEEAGRASASAEP 1441 Query: 402 KKRASIQRTSAPPSRPPPPRATASPRPSSGNI 433 + + PPS +AS R S + Sbjct: 1442 CPAEGTEEPTEPPSHLSETDPSASERQSGSQL 1473 >gi|21312134 mediator complex subunit 15 isoform b [Homo sapiens] Length = 748 Score = 58.2 bits (139), Expect = 2e-08 Identities = 47/199 (23%), Positives = 82/199 (41%), Gaps = 14/199 (7%) Query: 332 EEDEPLPACNGPAQAQPSPTTERAKSQEEVLPSS---TTP------SPGGALSPSGQPSS 382 + +P A N P+Q P T+ SQ + LP T P +P P QP Sbjct: 304 QPQQPPVAQNQPSQLPPQSQTQPLVSQAQALPGQMLYTQPPLKFVRAPMVVQQPPVQPQV 363 Query: 383 SATEVVLRTRTASEGSEQPKKRASIQRTSAPPSRPPPPRATASPRPSSGNIPSSPTASGG 442 + ++T ++ ++ + ++S P P P P S P P+ G Sbjct: 364 QQQQTAVQT---AQAAQMVAPGVQVSQSSLPMLSSPSPGQQVQT-PQSMPPPPQPSPQPG 419 Query: 443 GSPTSPRASLGTGTASPRTSLEVSPNPEPPEKPVRTPEAKENENIHNQNPEELCTSPTLM 502 + P +++ +G A +S SP+P+P + PV T +N ++ + P +P+ + Sbjct: 420 QPSSQPNSNVSSGPAPSPSSFLPSPSPQPSQSPV-TARTPQNFSVPSPGPLNTPVNPSSV 478 Query: 503 TSQVASEPGEAKKMEDKEK 521 S S E ++ DK K Sbjct: 479 MSPAGSSQAEEQQYLDKLK 497 >gi|163965366 nascent polypeptide-associated complex alpha subunit isoform a [Homo sapiens] Length = 2078 Score = 58.2 bits (139), Expect = 2e-08 Identities = 75/335 (22%), Positives = 123/335 (36%), Gaps = 41/335 (12%) Query: 265 PVRTATVSSPLTSPTSPSTLSLKS----------ESESVSATEDLAPDAAQGEDNSEIKE 314 P R + SP PTSP+ + L E + + DL P A + Sbjct: 1389 PKRGPAIPSPKGDPTSPAVIPLSPKKAPATPVTREGAATPSKGDLTPPAVTPVSLKKAPA 1448 Query: 315 LLEEEEIEKEGSEASSSEEDEPLPACNGPAQAQPSPTTERAKSQEEVLPSSTTPSPGGA- 373 K G SS+ D LPA P+ +P P ++ + + TP+P GA Sbjct: 1449 T----SAPKGGPATPSSKGDPTLPAVTPPSPKEP-PAPKQVATSSSPKKAPATPAPMGAP 1503 Query: 374 -------LSPSGQPSSSATEVVLRTRTASEGSEQPKKRASIQRTSAPPSR--PPPPRATA 424 SP P++ ++ TA+ S++ + + PP+ P P + A Sbjct: 1504 TLPAVIPSSPKEVPATPSSRRDPIAPTATLLSKKTPATLAPKEALIPPAMTVPSPKKTPA 1563 Query: 425 SPRPSSGNIPSSPTASGGGSPTSPRASLGTGTASPRTSLEVSPNPEPPEKPVRTPEA--- 481 P P P++P++ SP + S G SP+ L P K TP A Sbjct: 1564 IPTPKEA--PATPSSKEASSPPAVTPSTYKGAPSPKELLIPPAVTSPSPKEAPTPPAVTP 1621 Query: 482 -KENENIHNQNPEELCTSPTLMTSQVASEPGEAKKMEDK------EKDNKLISANSSEGQ 534 + P+ TSP + S + P + K + L + Sbjct: 1622 PSPEKGPATPAPKGTPTSPPVTPSSLKDSPTSPASVTCKMGATVPQASKGLPAKKGPTAL 1681 Query: 535 DQLQVSMVPENNN-LTAPE---PQEEVSTSENPQL 565 ++ V+ PE+ +TAP PQ + S++ +P + Sbjct: 1682 KEVLVAPAPESTPIITAPTRKGPQTKKSSATSPPI 1716 Score = 54.3 bits (129), Expect = 3e-07 Identities = 56/247 (22%), Positives = 86/247 (34%), Gaps = 35/247 (14%) Query: 250 KGLSSSSRRSLVISPPVRTA-------TVSSPLTSPTSPSTLSLKSESESVSATEDLAPD 302 KG+ +S +PP T SP +PT P+ + + + AP Sbjct: 928 KGIPASPSPKGAPTPPAATPPSPKGGPATPSPKWAPTPPAATPPSPKGGPATPSPKGAPT 987 Query: 303 AAQGEDNSEIKELLEEEEIEKEGSEASSSEEDEPLPACNGPAQAQPSPTTERAKSQEEVL 362 S +G A+ S + P P P + SP Sbjct: 988 PPAATPPSP------------KGGPATPSPKGAPTPPAVTPPSPKGSPAATPFPKGASTP 1035 Query: 363 PSSTTPSPGGALSPSGQPSSSATEVVLRTRTASEGSEQPKKRASIQRTSAPPSRPPPPRA 422 P++T PSP G+ + + P + T + G P + + +A P P P Sbjct: 1036 PAATPPSPKGSPAATPLPKGAPTTPAATLPSPKGGPATPSLKGAPTPPAATP--PSPKGG 1093 Query: 423 TASPRPSSGNIP---SSPTASGG-------GSPTSPRASLGTGTASPRTSLEVSPNPEPP 472 A+P P +P + P+ GG G+PT+P A+ SP+ L P P Sbjct: 1094 PATPSPKGAPMPPAATPPSPKGGLATPPHKGAPTTPAAT----PPSPKGGLATPPPKGAP 1149 Query: 473 EKPVRTP 479 P TP Sbjct: 1150 TTPAATP 1156 Score = 51.6 bits (122), Expect = 2e-06 Identities = 47/174 (27%), Positives = 70/174 (40%), Gaps = 16/174 (9%) Query: 324 EGSEASSSEEDEPLPACNGPAQAQPSPTTERAKSQEEVLPSSTTPSP-GGALSPSGQPSS 382 +G A+ S + P P P + P T K P++T PSP GG +PS + + Sbjct: 951 KGGPATPSPKWAPTPPAATPPSPKGGPATPSPKGAPTP-PAATPPSPKGGPATPSPKGAP 1009 Query: 383 SATEVVLRTRTASEGSEQPKKRASIQRTSAPPSRPPPPRATASPR----------PSSGN 432 + V + S + K AS + PPS P AT P+ PS Sbjct: 1010 TPPAVTPPSPKGSPAATPFPKGASTPPAATPPSPKGSPAATPLPKGAPTTPAATLPSPKG 1069 Query: 433 IPSSPTASGGGSP---TSPRASLGTGTASPR-TSLEVSPNPEPPEKPVRTPEAK 482 P++P+ G +P T P G T SP+ + + P P+ + TP K Sbjct: 1070 GPATPSLKGAPTPPAATPPSPKGGPATPSPKGAPMPPAATPPSPKGGLATPPHK 1123 Score = 51.2 bits (121), Expect = 2e-06 Identities = 65/314 (20%), Positives = 116/314 (36%), Gaps = 32/314 (10%) Query: 259 SLVISPPVRTATVSSPLTSPTSPSTLSLKSESESVSATEDLAPDAAQGEDNSEIKELLEE 318 ++ + P +T + +P +P +PS S+ S+ + P +G + KELL Sbjct: 1552 AMTVPSPKKTPAIPTPKEAPATPS-------SKEASSPPAVTPSTYKGAPSP--KELLIP 1602 Query: 319 EEIEKEGSEASSSEEDEPLPACNGPAQAQPSPTTERAKSQEEVLPSSTTPSPGGALSPSG 378 + S S ++ P P PA PSP A + P+S +P Sbjct: 1603 PAV------TSPSPKEAPTP----PAVTPPSPEKGPATPAPKGTPTSPPVTPSSLKDSPT 1652 Query: 379 QPSSSATEVVLRTRTASEGSEQPKKRASIQRTSAPPSRPPPPRATASPRPSSGNIPSSPT 438 P+S ++ AS+G K +++ P+ P TA R P + Sbjct: 1653 SPASVTCKMGATVPQASKGLPAKKGPTALKEVLVAPAPESTPIITAPTRKG----PQTKK 1708 Query: 439 ASGGGSPTSPRASLGTGTASPRTSLEVSPNPEPPEKPVRTPEAKENENIHNQN-----PE 493 +S P P S G+ P ++ V+P P P + + AK + H+ PE Sbjct: 1709 SSATSPPICPDPSAKNGSKGPLST--VAPAPLLPVQKDSSKTAKGKDASHSPKGPLAPPE 1766 Query: 494 ELCTSPTLMTS--QVASEPGEAKKMEDKEKDNKLISANSSEGQDQLQVSMVPENNNLTAP 551 ++P + +V +P A L A S + +P + L Sbjct: 1767 SKASTPLTAAAFEKVLPKPESASVSAAPSPPVSLPLAPSPVPTLPPKQQFLPSSPGLVLE 1826 Query: 552 EPQEEVSTSENPQL 565 P + ++ ++ +L Sbjct: 1827 SPSKPLAPADEDEL 1840 Score = 49.3 bits (116), Expect = 9e-06 Identities = 75/285 (26%), Positives = 108/285 (37%), Gaps = 56/285 (19%) Query: 249 VKGLSSSSRRSLVISPPVR--------TATVSSP-----LTSPTSPSTLSLKSESESVSA 295 V G+S +S + V S P +AT SS L SP +S+ +++ Sbjct: 751 VDGISHTSALAPVASSPKECPTEDSGASATASSKGTLTYLADSPSPLGVSVSPQTKRPPT 810 Query: 296 TEDLA-PDAAQGEDNSEIKEL----LEEEEIEKEGSEASSSEEDEPLPACNGPAQAQPSP 350 + A PD G +S + + L E + +GS+ S + P P + P+P Sbjct: 811 KKGSAGPDTPIGNLSSPVSPVEASFLPENSLSFQGSKDSPATTHSPTPPS---PKGAPTP 867 Query: 351 TTERAKSQEEV-LPSSTTPSPGGALSPSGQPSSSATEVVLRTRTASEGSEQPKKRAS--- 406 + S + V LP TP+P P + AT + S S PKK + Sbjct: 868 SAVTPLSPKGVTLPPKETPTPSVVNLPFPK-EGPATPAPKQAPALSMTSSSPKKARATPA 926 Query: 407 ---IQRTSAPPSRPPPPRATA--------------SPRPSSGNIPS----SPTASGGGSP 445 I + +P P PP AT +P P + PS T S G+P Sbjct: 927 PKGIPASPSPKGAPTPPAATPPSPKGGPATPSPKWAPTPPAATPPSPKGGPATPSPKGAP 986 Query: 446 TSPRASL-----GTGTASPR---TSLEVSPNPEPPEKPVRTPEAK 482 T P A+ G T SP+ T V+P P P P TP K Sbjct: 987 TPPAATPPSPKGGPATPSPKGAPTPPAVTP-PSPKGSPAATPFPK 1030 Score = 45.1 bits (105), Expect = 2e-04 Identities = 84/331 (25%), Positives = 132/331 (39%), Gaps = 65/331 (19%) Query: 250 KGLSSSSRRSLVISPPVRTATVSSPLTSPTSPSTLSLKSESESVSATEDLAPDAAQGEDN 309 KG ++ + + SPPV +++ SPTSP++++ K + A++ L A +G Sbjct: 1626 KGPATPAPKGTPTSPPVTPSSLKD---SPTSPASVTCKMGATVPQASKGL--PAKKGP-- 1678 Query: 310 SEIKELLEEEEIE---------KEGSEASSSEEDEPLPACNGPAQAQPSPTTERAKSQEE 360 + +KE+L E ++G + S P P C P+ S + Sbjct: 1679 TALKEVLVAPAPESTPIITAPTRKGPQTKKSSATSP-PICPDPSAKNGSKGPLSTVAPAP 1737 Query: 361 VLP-----SSTTPSPGGALSPSG---QPSSSATEVVLRTRTASEGSEQPKKRASIQRTSA 412 +LP S T + SP G P S A+ + T A E + AS+ + Sbjct: 1738 LLPVQKDSSKTAKGKDASHSPKGPLAPPESKASTPL--TAAAFEKVLPKPESASVSAAPS 1795 Query: 413 PP-SRP--PPPRATASPR----PSSGNI----PSSPTASGGGS---PTSPRASLGTGTAS 458 PP S P P P T P+ PSS + PS P A P P + G Sbjct: 1796 PPVSLPLAPSPVPTLPPKQQFLPSSPGLVLESPSKPLAPADEDELLPLIPPEPISGGV-- 1853 Query: 459 PRTSLEVS-PNPEPPEKPVRTPEAKENENIHNQN--------------PEELCTSPTLMT 503 P S+ V+ P P+ PV TP AK+ +N+ E+ T T Sbjct: 1854 PFQSVLVNMPTPKSAGIPVPTPSAKQPVTKNNKGSGTESDSDESVPELEEQDSTQATTQQ 1913 Query: 504 SQVAS------EP-GEAKKMEDKEKDNKLIS 527 +Q+A+ EP +AK+ ++K K +S Sbjct: 1914 AQLAAAAEIDEEPVSKAKQSRSEKKARKAMS 1944 Score = 44.7 bits (104), Expect = 2e-04 Identities = 78/341 (22%), Positives = 114/341 (33%), Gaps = 38/341 (11%) Query: 255 SSRRSLVISPPVRTATVSSPLTSPTSPSTLSLKSESESVSATEDLAPDAAQGEDNSEIKE 314 S + L PP T +P +P SP + T P + +G + + Sbjct: 1158 SPKGGLATPPPKGAPT--TPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPK 1215 Query: 315 LLEEEEIEKEGSEASSSEEDEPLPACNGPAQAQPSPTTERAKSQEE---VLPSSTTPSPG 371 S P A PA PSP A + P++T PS Sbjct: 1216 GAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGPATPPPKGAPTPPAATPPSLK 1275 Query: 372 GALSPSGQPSSSATEVVLRTRTASEGSEQPKKRASIQRTSAPPSRP-----PPPRATASP 426 G L+ + VV + P K A + PPS PPP+ +P Sbjct: 1276 GGLATPPHKGAPNPAVVTPPSPKGGPATSPPKGAPTPPAATPPSPKGSPGTPPPKGAPTP 1335 Query: 427 R----PSSGNIPSSP--TASGGGSPTSPRASLGTGTASPRTSLEVSPNPEPPEKPVRTPE 480 PS P+ P T S G PT+P + G + S + P PP P R P Sbjct: 1336 PAVTPPSPKGTPTLPATTPSSKGGPTTPSSKEGPTPPAATPSHKGGPAMTPP-SPKRGP- 1393 Query: 481 AKENENIHNQNPEELCTSP-----TLMTSQVASEPGEA------------KKMEDKEKDN 523 A + +P + SP T +T + A+ P + KK Sbjct: 1394 AIPSPKGDPTSPAVIPLSPKKAPATPVTREGAATPSKGDLTPPAVTPVSLKKAPATSAPK 1453 Query: 524 KLISANSSEGQDQLQVSMVPENNNLTAPEPQEEVSTSENPQ 564 + SS+G L P AP ++V+TS +P+ Sbjct: 1454 GGPATPSSKGDPTLPAVTPPSPKEPPAP---KQVATSSSPK 1491 Score = 42.0 bits (97), Expect = 0.001 Identities = 60/248 (24%), Positives = 93/248 (37%), Gaps = 22/248 (8%) Query: 263 SPPVRTATVSSPLTSPTSPSTLSLKSESESVSATEDLAPDAAQGEDNSEIKELLEEEEIE 322 +P AT SP P +PS + + +P A + Sbjct: 985 APTPPAATPPSPKGGPATPSPKGAPTPPAVTPPSPKGSPAATPFPKGASTPPAATPPS-- 1042 Query: 323 KEGSEASSSEEDEPLP--ACNGPAQAQPSPTTERAKSQEE---VLPSSTTPSP-GGALSP 376 +GS A++ PLP A PA PSP A + P++T PSP GG +P Sbjct: 1043 PKGSPAAT-----PLPKGAPTTPAATLPSPKGGPATPSLKGAPTPPAATPPSPKGGPATP 1097 Query: 377 SGQPSSSATEVVLRTRTASEGSEQPKKRASIQRTSAPPSRPPPPRATASPRPSSGNIPSS 436 S P + + G P + + +A P P AT P+ + ++ Sbjct: 1098 S--PKGAPMPPAATPPSPKGGLATPPHKGAPTTPAATPPSPKGGLATPPPKGAPTTPAAT 1155 Query: 437 PTASGGGSPTSPRASLGTGTA----SPRTSLEVSPNPE-PPEKPVRTPEAKENENIHNQN 491 P + GG T P T A SP+ L +P+P+ P P TP + + + + Sbjct: 1156 PPSPKGGLATPPPKGAPTTPAATPPSPKGGL-ATPSPKGAPTTPAATPPSPKG-GLATPS 1213 Query: 492 PEELCTSP 499 P+ T+P Sbjct: 1214 PKGAPTTP 1221 Score = 33.1 bits (74), Expect = 0.70 Identities = 67/301 (22%), Positives = 108/301 (35%), Gaps = 53/301 (17%) Query: 261 VISPPVRTATVSSPLTSPTSPSTLSLKS------------------ESESVSATEDLAPD 302 + SP V+ T+SS L SP +P +LSLK S +A + PD Sbjct: 241 IASPQVKDTTISSVLISPQNPGSLSLKGPVSPPAALSLSTQSLPVVTSSQKTAGPNTPPD 300 Query: 303 ---------AAQGEDNSEIKELLEE-----------EEIEKEGSEASSSEEDE-----PL 337 A + + +LL + + I + S +S + PL Sbjct: 301 FPISLGSHLAPLHQSSFGSVQLLGQTGPSALSDPTVKTISVDHSSTGASYPSQRSVIPPL 360 Query: 338 PACNG--PAQAQPSPTTERAKSQEEVLPSSTTPSPGGALSPSGQPSSSATEVVLRTRTAS 395 P+ N PA P + + SS T SP G+L+ + S S T ++ + + Sbjct: 361 PSRNEVVPATVAAFPVVAPSVDKGPSTISSITCSPSGSLNVATSFSLSPTTSLILKSSPN 420 Query: 396 EGSEQP----KKRASIQRTSAPPSRPPPPRATASPRPSSGNIPSSPTASGGGS---PTSP 448 P +S+ T + P A + S P +SG S PTSP Sbjct: 421 ATYHYPLVAQMPVSSVGTTPLVVTNPCTIAAAPTTTFEVATCVSPPMSSGPISNIEPTSP 480 Query: 449 RASLGTGTASPRTSLEVSPNPEPPEKPVRTPEAKENENIHNQNPEELCTSPTLMTSQVAS 508 A + A S +V+ P P P+ ++ +N+ + + T L T + Sbjct: 481 AALVMAPVAPKEPSTQVATTLRIPVSP-PLPDPEDLKNLPSSVLVKFPTQKDLQTVPASL 539 Query: 509 E 509 E Sbjct: 540 E 540 Score = 29.6 bits (65), Expect = 7.7 Identities = 17/51 (33%), Positives = 22/51 (43%) Query: 401 PKKRASIQRTSAPPSRPPPPRATASPRPSSGNIPSSPTASGGGSPTSPRAS 451 PK S Q TS+ P P P AT + + +P AS SP +S Sbjct: 567 PKNSPSFQSTSSSPEIPLSPEATLAKKSLGEPLPIGKPASSMTSPLGVNSS 617 >gi|39930351 dynamin binding protein [Homo sapiens] Length = 1577 Score = 56.6 bits (135), Expect = 6e-08 Identities = 95/474 (20%), Positives = 177/474 (37%), Gaps = 68/474 (14%) Query: 19 KKFSRAQEKVLQKLGKAVETKDERFEQSASNFYQQQAEGHKLYKDLKNFLSAVKVMHESS 78 KK +R + G A + KDE FE++ NF Q+ +DL +L + Sbjct: 999 KKSNRVSSHLKHLTGFAPQIKDEVFEETEKNFRMQERLIKSFIRDLSLYLQHI------- 1051 Query: 79 KRVSETLQEIYS-SEWD-----GHEELKAIV----WNNDLLWEDYEEKLADQAVRTMEIY 128 R S ++ + + S WD GH +L+ + +D L+ +++E+ + + Sbjct: 1052 -RESACVKVVAAVSMWDVCMERGHRDLEQFERVHRYISDQLFTNFKERTERLVISPLNQL 1110 Query: 129 VAQFSEIKERIAKRGRKLVDYDSARHHLEAVQNAKKKDEAKTAKAEEEFNKAQTVFEDLN 188 ++ F+ + + KR KL+D+ + ++ ++ K K EE A+ +E LN Sbjct: 1111 LSMFTGPHKLVQKRFDKLLDFYNC---------TERAEKLKDKKTLEELQSARNNYEALN 1161 Query: 189 QELLEELPILYNSRIGCYVTIFQNIS----------------------------NLRDVF 220 +LL+ELP + G + + NL +F Sbjct: 1162 AQLLDELPKFHQYAQGLFTNCVHGYAEAHCDFVHQALEQLKPLLSLLKVAGREGNLIAIF 1221 Query: 221 YREMSKLNHNLYEVMSKLEK-QHSNKVFVVKGLSSSSRRSLVISPP---VRTATVSSPLT 276 + E S++ L E + K F K + S R ++ P +++ + + L Sbjct: 1222 HEEHSRVLQQLQVFTFFPESLPATKKPFERKTIDRQSARKPLLGLPSYMLQSEELRASLL 1281 Query: 277 SPTSPSTLSLKSESESVSATEDLAPDAAQGEDNSEIKELLEEEEIEKEGSEASSSEEDEP 336 + P L + +A +DL +G+ IK+ + GS+ ++ Sbjct: 1282 ARYPPE--KLFQAERNFNAAQDLDVSLLEGDLVGVIKKK------DPMGSQNRWLIDNGV 1333 Query: 337 LPACNGPAQAQPSPTTERAKSQEEVLPSSTTPSPGGALSPSGQPSSSATEVVLRTRTASE 396 + +P R+ S V S+T S G+ SP +S + + + + Sbjct: 1334 TKGFVYSSFLKPY-NPRRSHSDASVGSHSSTESEHGSSSPRFPRQNSGSTLTFNPSSMAV 1392 Query: 397 GSEQPKKRASIQRTSAPPSRPPPPRATASPRPSSGNIPSSPTASGGGSPTSPRA 450 + Q S PP +AS PS+ S S S + PR+ Sbjct: 1393 SFTSGSCQKQPQDASPPPKECDQGTLSASLNPSNSESSPSRCPSDPDSTSQPRS 1446 >gi|239740773 PREDICTED: similar to diffuse panbronchiolitis critical region 1 [Homo sapiens] Length = 1400 Score = 56.2 bits (134), Expect = 8e-08 Identities = 73/310 (23%), Positives = 111/310 (35%), Gaps = 39/310 (12%) Query: 279 TSPSTLSLKSESESVSATEDLAPDAAQGEDNSEIKELLEEEEIEKEGSEASSSEEDEPLP 338 T+PS E +A E+ P A+ ++ E ++ S A S+E E P Sbjct: 435 TTPSPAEPTEHGER-TANENTTPSPAEPTEHGERTPFANDKTTS---SSAESTEHGERTP 490 Query: 339 ACNGPAQAQPSPTTERAKSQEEVLPSSTTPSPGGALSPSGQPSSSATEVVL--------- 389 N P+ TE ++E +TTPSP G P+ ++A E Sbjct: 491 LANENTTPSPAEPTE---NRERTANENTTPSPAG---PTENRETTANEKTTLSPVEPTEN 544 Query: 390 RTRTASE------------GSEQPKKRASIQRTSAPPS----RPPPPRATASPRPSSGNI 433 R TA+E G P +SA P+ R P +P P+ Sbjct: 545 RETTANEKTTPSPAEPTENGQRTPFANEKTTSSSAEPTEHGERTPLANENTTPSPAEPTE 604 Query: 434 PSSPTASGGGSPTSPRASLGTGTASPRTSLEVSPN-PEPPEKPVRTPEAKENENIHNQNP 492 TA+ +P SP G +P + + +P+ EP E RTP A E + P Sbjct: 605 NRERTANEKTTP-SPAEPTENGDRTPLANEKTTPSLAEPTENGQRTPFANEKTTSSSAEP 663 Query: 493 EELCTSPTLMTSQVASEPGEAKKMEDKEKDNKLISANSSEGQDQLQVSMVPENNNLTAPE 552 E L + P A+ E++E+ + S G + + E L E Sbjct: 664 TEHEERTPLANEN--TTPSPAEPTENRERTANENTTPSPAGPTENREMTANEKTTLFPAE 721 Query: 553 PQEEVSTSEN 562 P E + N Sbjct: 722 PTENRERTAN 731 Score = 52.8 bits (125), Expect = 8e-07 Identities = 69/296 (23%), Positives = 115/296 (38%), Gaps = 30/296 (10%) Query: 267 RTATVSSPLTSPTSPSTLSLKSESESVSATEDLAPDAAQGEDNSEIKELLEEEEIEKEGS 326 RTA ++ L SP P+ E+ +A E+ AP A +N E+ E + Sbjct: 372 RTANENTTL-SPAEPT------ENRERTANENTAPFPAGPTENREMTANENTTLFPAEPT 424 Query: 327 EASSSEEDEPLPACNGPAQAQPSPTTERAKSQEEVLPSSTTPSPGGALSP-----SGQPS 381 E +E P+ A+P+ ER + E PS P+ G +P + S Sbjct: 425 EHGERTANENTT----PSPAEPTEHGERT-ANENTTPSPAEPTEHGERTPFANDKTTSSS 479 Query: 382 SSATEVVLRTRTASEGSE-QPKKRASIQRTSAPPSRPPPPRATASPRPSSGNIPSSPTAS 440 + +TE RT A+E + P + + +A + P P R ++ N ++ Sbjct: 480 AESTEHGERTPLANENTTPSPAEPTENRERTANENTTPSPAGPTENRETTANEKTTL--- 536 Query: 441 GGGSPTSPRASLGTGTASPRTSLEVSPNP-EPPEKPVRTPEAKENENIHNQNPEELCTSP 499 SP P + T TA+ +T+ P+P EP E RTP A E + P E Sbjct: 537 ---SPVEPTENRET-TANEKTT----PSPAEPTENGQRTPFANEKTTSSSAEPTEHGERT 588 Query: 500 TLMTSQVASEPGEAKKMEDKEKDNKLISANSSEGQDQLQVSMVPENNNLTAPEPQE 555 L P E + ++ + K + + ++ + + E + EP E Sbjct: 589 PLANENTTPSPAEPTENRERTANEKTTPSPAEPTENGDRTPLANEKTTPSLAEPTE 644 Score = 52.4 bits (124), Expect = 1e-06 Identities = 74/341 (21%), Positives = 111/341 (32%), Gaps = 53/341 (15%) Query: 263 SPPVRTATVSSPLTSPTSPSTLSLKSESESVS-ATEDLAPDAAQGEDNSEIKELLEEEEI 321 SP T T+PS + A E P A+ +N + E+ Sbjct: 598 SPAEPTENRERTANEKTTPSPAEPTENGDRTPLANEKTTPSLAEPTENGQRTPFANEKTT 657 Query: 322 EKEGSEASSSEEDEPLPACNGPAQAQPSPTTERAKSQEEVLPSSTTPSPGGALSPSGQPS 381 S A +E +E P N P+ TE ++E +TTPSP G + Sbjct: 658 S---SSAEPTEHEERTPLANENTTPSPAEPTE---NRERTANENTTPSPAGPTENREMTA 711 Query: 382 SSATEVVL------RTRTASE------------GSEQPKKRASIQRTSAPPS----RPP- 418 + T + R RTA+E G P +SA P+ R P Sbjct: 712 NEKTTLFPAEPTENRERTANEKTTSSPAEPTENGQRTPFANEKTTSSSAEPTEHGERTPL 771 Query: 419 -PPRATASPRPSSGN-----------IPSSPT-----ASGGGSPTSPRASLGTGTASPRT 461 T SP + N P+ PT + + SP G +P Sbjct: 772 ANENTTLSPAGPTENRERTANEKTTPFPAEPTENRERTANENTTPSPAQPTENGDRTPLA 831 Query: 462 SLEVSPN-PEPPEKPVRTPEAKENENIHNQNPEELCTSPTLMTSQVASEPGEAKKMEDKE 520 + + +P+ EP E RTP A E + P E L S P E + ++ Sbjct: 832 NEKTTPSLAEPTENGKRTPFANEKTTSSSAEPTEHAERTPLANENTTSSPAEPTENRERT 891 Query: 521 KDNKLISANSSEGQDQLQVSMVPENNNLTAPEPQEEVSTSE 561 + K + +++ + N T P P E E Sbjct: 892 ANEKTTQFPAEPTENRESTA-----NEKTTPFPAEPTENRE 927 Score = 37.0 bits (84), Expect = 0.048 Identities = 56/275 (20%), Positives = 99/275 (36%), Gaps = 28/275 (10%) Query: 252 LSSSSRRSLVISPPVRTATVSSPLTSPTSPSTLSLKS-------ESESVSATEDLAPDAA 304 ++ SS V S T S+ ++ P + S L+L+S + + S+T P A Sbjct: 1013 ITMSSAAIPVSSTAYETIRFSTAVSEPVTASILALESTLAFTTVSNTTTSSTVTSVPTTA 1072 Query: 305 Q---GEDNSEIKELLEEEEIEK--EGSEASSSEEDEPLPACNGPAQAQPSPTTERAKSQE 359 ++ + + + E I + + S + + A + P A +PT S Sbjct: 1073 STSGSKNTTACEATMSETTIAAITASEDTTVSTQTSVIAAESVPHTATKTPTDTTTASVS 1132 Query: 360 EVLPSSTTPSPGGALSPSGQPSSSATEVVLRTRTASEGSEQPKKRASIQRTSAPPSRPPP 419 +P + T S + +PS P++++ + ++T + TS S P Sbjct: 1133 ATVPKNNTLSVITS-TPSTAPNTASKTMTTASKTTT--------------TSTITSLPTT 1177 Query: 420 PRATASPRPSSGNIPSSPTASGGGSPTSPRASLGTGTASPRTSLEVSPNPEPPEKPVRT- 478 T S + IP++ T + S +AS T ++P T+ P T Sbjct: 1178 VFTTTSKITAGSEIPTASTTDSATTAISTKASGTTVESAPSTAPPTPAETTTASVPTTTS 1237 Query: 479 PEAKENENIHNQNPEELCTSPTLMTSQVASEPGEA 513 EN H + T S SE A Sbjct: 1238 TTGSENTGHHTVSSVPTTVFATASESSTGSETTRA 1272 Score = 32.3 bits (72), Expect = 1.2 Identities = 61/289 (21%), Positives = 104/289 (35%), Gaps = 47/289 (16%) Query: 239 EKQHSNKVFVVKGLSSSSRR-SLVISPPVRTATVSSPLTSPTSPSTLSLKSESESVSATE 297 E + + V + L + R+ S P ATV+S S +S ++ + S + SVSAT Sbjct: 943 EHEEMTPLMVDENLQAPFRQGSCAERPKDICATVASTTGSESSTASEIITSSTMSVSATA 1002 Query: 298 DLAPDAAQGE-------------------DNSEIKELLEEEEIEKEG-------SEASSS 331 + E ++ + E + + E S ++S Sbjct: 1003 SSTASSTASEITMSSAAIPVSSTAYETIRFSTAVSEPVTASILALESTLAFTTVSNTTTS 1062 Query: 332 EEDEPLPACNGPAQAQPSPTTERAKSQEEV----LPSSTTPSPGGALSPSGQPSSSATEV 387 +P + ++ + E S+ + TT S ++ + +AT+ Sbjct: 1063 STVTSVPTTASTSGSKNTTACEATMSETTIAAITASEDTTVSTQTSVIAAESVPHTATKT 1122 Query: 388 VLRTRTASEGSEQPKKRASIQRTSAP---PSRPPPPRATASPRPSSGNIPSSPT------ 438 T TAS + PK TS P P+ TAS ++ I S PT Sbjct: 1123 PTDTTTASVSATVPKNNTLSVITSTPSTAPNTASKTMTTASKTTTTSTITSLPTTVFTTT 1182 Query: 439 ---ASGGGSP---TSPRASLGTGTASPRTSLEVSPNPEPPEKPVRTPEA 481 +G P T+ A+ T + T++E +P+ PP P T A Sbjct: 1183 SKITAGSEIPTASTTDSATTAISTKASGTTVESAPSTAPP-TPAETTTA 1230 >gi|20143482 melanoma antigen family E, 1 [Homo sapiens] Length = 957 Score = 55.8 bits (133), Expect = 1e-07 Identities = 75/292 (25%), Positives = 104/292 (35%), Gaps = 55/292 (18%) Query: 302 DAAQGEDNSEIKELLEEEEIEKEGSEASSSEEDEPLP-ACNGPAQAQPSPTTERAKSQE- 359 D QG +S+I + G AS LP + GP+ P PT A S Sbjct: 44 DVPQGPSDSQILQ----------GLCASEGPSTSVLPTSAEGPSTFVP-PTISEASSASG 92 Query: 360 -----EVLPSSTTPSPGGALSPSGQPSSSATEVVLRTRTASEG--SEQPKKRASIQRTSA 412 E +S P+P LS SG P+ S T ASEG + +P + TS Sbjct: 93 QPTISEGPGTSVLPTPSEGLSTSGPPTISKGLCTSVTLAASEGRNTSRPPTSSEEPSTSV 152 Query: 413 PPSRPPPPRATASPRPSSGNIPSSPTASGGGSPTS--------------PRASLGTGTAS 458 PP+ P + P P G S P + G TS P G GT+ Sbjct: 153 PPTASEVPSTSLPPTPGEGTSTSVPPTAYEGPSTSVVPTPDEGPSTSVLPTPGEGPGTSV 212 Query: 459 PRTS---LEVSPNPEPPEKPVRTPEAKENENIHNQNPEELCTSPTLMTSQVASEPGEAKK 515 P + L S P E P + E + P P ++ V + PGE Sbjct: 213 PLAATEGLSTSVQATPDEGPSTSVPPTATEGLSTPVPPTRDEGP---STSVPATPGEGPS 269 Query: 516 MEDKEKDNKLISANSSEGQDQLQVSMVPE----NNNLTAPEPQEEVSTSENP 563 + +S+GQ +S+VP ++ P E +STS P Sbjct: 270 TS--------VLPAASDGQ---SISLVPTRGKGSSTSVPPTATEGLSTSVQP 310 Score = 47.4 bits (111), Expect = 4e-05 Identities = 74/313 (23%), Positives = 118/313 (37%), Gaps = 31/313 (9%) Query: 259 SLVISPPVRTATVSSPLTSPTSPSTLSLKSESESVSATEDLAPDAAQGEDNSEIKELLEE 318 SL +P T+T S P T+ PST + + E S + + P +G S Sbjct: 163 SLPPTPGEGTST-SVPPTAYEGPSTSVVPTPDEGPSTS--VLPTPGEGPGTSV------- 212 Query: 319 EEIEKEGSEASSSEEDEPLPACNGPAQAQPSPTTERAKSQEEVLPSSTTPSPGGALSPSG 378 EG S + P+ + P A +T +++E +S +PG S S Sbjct: 213 PLAATEGLSTSVQATPDEGPSTSVPPTATEGLSTPVPPTRDEGPSTSVPATPGEGPSTSV 272 Query: 379 QPSSSATEVVLRTRTASEGSEQPKKRASIQRTSAPPSRPPPPRATASPRPSSGNIPSSPT 438 P++S + + T +GS TS PP+ + P G+ S P Sbjct: 273 LPAASDGQSISLVPTRGKGSS----------TSVPPTATEGLSTSVQPTAGEGSSTSVPP 322 Query: 439 ASGGGSPTS--PRASLGTGTASPRT-----SLEVSPNPEPPEKPVRTPEAKENENIHNQN 491 GGG TS P A+ T+ P T S V P P P A + + + Sbjct: 323 TPGGGLSTSVPPTATEELSTSVPPTPGEGPSTSVLPIPGEGLSTSVPPTASDGSDT-SVP 381 Query: 492 PEELCTSPTLMTSQVASEPGEAKKMEDKEKDNKLISANSSEGQDQLQVSMVPENNNLTAP 551 P + TL+ PG + E + L S+++S ++ + S+V + +T Sbjct: 382 PTPGEGASTLVQPTAPDGPGSSVLPNPGEGPSTLFSSSASVDRNPSKCSLVLPSPRVTKA 441 Query: 552 EPQEEVSTSENPQ 564 S SE P+ Sbjct: 442 SVD---SDSEGPK 451 >gi|239751395 PREDICTED: hypothetical protein, partial [Homo sapiens] Length = 306 Score = 55.1 bits (131), Expect = 2e-07 Identities = 62/224 (27%), Positives = 95/224 (42%), Gaps = 20/224 (8%) Query: 263 SPPVRTATVSSPLTSPTSPSTLS-LKSESESVSATEDLAPDAAQGEDNSEIKELLEEEEI 321 S P+ T + S+P +P+SP TL+ + + + S T L P + S L + + Sbjct: 30 SQPILTRS-STPTLTPSSPPTLTPSNTPTLTPSNTPTLTPSSTPTLTPSSTPTLTPQPIL 88 Query: 322 EKEGSEASSSEEDEPLPACNGPAQAQPSPTTERAKSQEEVLPSSTTPSPGGALSPSGQPS 381 + + + L N P PS T S L S+TP+ L+PS P+ Sbjct: 89 TRSSTPTLTPSSPPTLTPSNTPT-LTPSNTPTLTPSNTPTLTPSSTPT----LTPSSTPT 143 Query: 382 SSATEVVLRTRTASEGSEQPKKRASIQRTSAP---PSRPP--PPRATASPRPSSGNIPSS 436 + + + TR +S + P R + R+S P PS P P +T + PS S+ Sbjct: 144 LTPSSRPILTR-SSTPTLTPSSRPILTRSSTPTLTPSSTPTLTPSSTPTLTPS-----ST 197 Query: 437 PTASGGGSPTSPRASLGTGTASPRTSLEVSPNP--EPPEKPVRT 478 PT + P R+S T T S R L S P P +P+ T Sbjct: 198 PTLTPSSRPILTRSSTPTLTPSSRPILTPSSTPTLTPSSRPILT 241 Score = 44.7 bits (104), Expect = 2e-04 Identities = 42/157 (26%), Positives = 65/157 (41%), Gaps = 19/157 (12%) Query: 341 NGPAQAQPSPTTERAKSQEEVLPSSTTPSPGGALSPSGQPSSSATEVVLRTRTASEGSEQ 400 + P PS T S + +L S+TP+ + P+ PS++ T T T + S Sbjct: 13 SSPPTLTPSSTPTLTPSSQPILTRSSTPTLTPSSPPTLTPSNTPTLTPSNTPTLTPSSTP 72 Query: 401 PKKRAS---------IQRTSAP---PSRPPPPRATASPRPSSGNIP-----SSPTASGGG 443 +S + R+S P PS PP + +P + N P ++PT + Sbjct: 73 TLTPSSTPTLTPQPILTRSSTPTLTPSSPPTLTPSNTPTLTPSNTPTLTPSNTPTLTPSS 132 Query: 444 SPTSPRASLGTGTASPRTSLEVSPNP--EPPEKPVRT 478 +PT +S T T S R L S P P +P+ T Sbjct: 133 TPTLTPSSTPTLTPSSRPILTRSSTPTLTPSSRPILT 169 Score = 44.7 bits (104), Expect = 2e-04 Identities = 61/232 (26%), Positives = 93/232 (40%), Gaps = 23/232 (9%) Query: 252 LSSSSRRSLVISPPVRTATVSSPLTSPTSPSTLSLKSESESVSATEDLAPDAAQGEDNSE 311 L+ SS +L P + + S+P +P+SP TL+ S T L P S Sbjct: 74 LTPSSTPTLTPQPILTRS--STPTLTPSSPPTLT-------PSNTPTLTPSNTPTLTPSN 124 Query: 312 IKELLEEEEIEKEGSEASSSEEDEPLPACNGPAQAQPSPTTERAKSQEEVLPSSTTPSPG 371 L S + + P + S T S +L S+TP+ Sbjct: 125 TPTLTPS-------STPTLTPSSTPTLTPSSRPILTRSSTPTLTPSSRPILTRSSTPTLT 177 Query: 372 GALSPSGQPSSSATEVVLRTRTASEGSEQPKKRASIQRTSAPPSRP-PPPRATASPRPSS 430 + +P+ PSS+ T T T + S R+S T P SRP P +T + PSS Sbjct: 178 PSSTPTLTPSSTPTLTPSSTPTLTPSSRPILTRSSTP-TLTPSSRPILTPSSTPTLTPSS 236 Query: 431 GNI---PSSPTASGGGSPTSPRASLGTGTASPRTSLEVSPNPEPPEKPVRTP 479 I S+PT + +PT ++ T T +P + ++P+ P P TP Sbjct: 237 RPILTRSSTPTLTPSSTPTLTPSN--TPTLTPSNTPTLTPSNTPTLTPSSTP 286 Score = 38.9 bits (89), Expect = 0.013 Identities = 39/167 (23%), Positives = 62/167 (37%), Gaps = 11/167 (6%) Query: 326 SEASSSEEDEPLPACNGPAQAQPSPTTERAKSQEEVLPSSTTPSPGGALSPSGQPSSSAT 385 S + + +P+ + PS S L S TP+ + +P+ PSS+ T Sbjct: 22 STPTLTPSSQPILTRSSTPTLTPSSPPTLTPSNTPTLTPSNTPTLTPSSTPTLTPSSTPT 81 Query: 386 ----EVVLRTRTASEGSEQPKKRASIQRTSAPPSRPPPPRATASPRPSSGNIP-----SS 436 ++ R+ T + P + PS P + +P + + P S+ Sbjct: 82 LTPQPILTRSSTPTLTPSSPPTLTPSNTPTLTPSNTPTLTPSNTPTLTPSSTPTLTPSST 141 Query: 437 PTASGGGSPTSPRASLGTGTASPRTSLEVSPNP--EPPEKPVRTPEA 481 PT + P R+S T T S R L S P P P TP + Sbjct: 142 PTLTPSSRPILTRSSTPTLTPSSRPILTRSSTPTLTPSSTPTLTPSS 188 Score = 38.5 bits (88), Expect = 0.017 Identities = 36/141 (25%), Positives = 53/141 (37%), Gaps = 15/141 (10%) Query: 367 TPSPGGALSPSGQPSSSATEVVLRTRTASEGSEQPKKRASIQRTSAP---PSRPPPPRAT 423 TPS L+PS P+ + + T P + + R+S P PS PP + Sbjct: 3 TPSNTPTLTPSSPPTLTPSSTPTLT---------PSSQPILTRSSTPTLTPSSPPTLTPS 53 Query: 424 ASPRPSSGNIPSSPTASGGGSPTSPRASLGTGTASPRTSLEVSPNPEPPEKPVRTPEAKE 483 +P + N +PT + +PT +S T T P + +P P P TP Sbjct: 54 NTPTLTPSN---TPTLTPSSTPTLTPSSTPTLTPQPILTRSSTPTLTPSSPPTLTPSNTP 110 Query: 484 NENIHNQNPEELCTSPTLMTS 504 N +PTL S Sbjct: 111 TLTPSNTPTLTPSNTPTLTPS 131 Score = 31.6 bits (70), Expect = 2.0 Identities = 31/137 (22%), Positives = 52/137 (37%), Gaps = 1/137 (0%) Query: 263 SPPVRTATVSSPLTSPTSPSTLSLKSESESVSATEDLAPDAAQGEDNSEIKELLEEEE-I 321 S P+ T + + LT ++P+ + + + S+T L P + S L I Sbjct: 164 SRPILTRSSTPTLTPSSTPTLTPSSTPTLTPSSTPTLTPSSRPILTRSSTPTLTPSSRPI 223 Query: 322 EKEGSEASSSEEDEPLPACNGPAQAQPSPTTERAKSQEEVLPSSTTPSPGGALSPSGQPS 381 S + + P+ + PS T S L S TP+ + +P+ PS Sbjct: 224 LTPSSTPTLTPSSRPILTRSSTPTLTPSSTPTLTPSNTPTLTPSNTPTLTPSNTPTLTPS 283 Query: 382 SSATEVVLRTRTASEGS 398 S+ T T T + S Sbjct: 284 STPTLTPSSTPTLTPSS 300 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.303 0.120 0.324 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 24,409,867 Number of Sequences: 37866 Number of extensions: 1433625 Number of successful extensions: 23668 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 444 Number of HSP's successfully gapped in prelim test: 2335 Number of HSP's that attempted gapping in prelim test: 12062 Number of HSP's gapped (non-prelim): 9062 length of query: 565 length of database: 18,247,518 effective HSP length: 108 effective length of query: 457 effective length of database: 14,157,990 effective search space: 6470201430 effective search space used: 6470201430 T: 11 A: 40 X1: 17 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 43 (21.8 bits) S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.