Guide to the Human Genome
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Search of human proteins with 4885381

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|4885381 histone cluster 1, H1b [Homo sapiens]
         (226 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|4885381 histone cluster 1, H1b [Homo sapiens]                      427   e-120
gi|4885379 histone cluster 1, H1e [Homo sapiens]                      337   5e-93
gi|4885377 histone cluster 1, H1d [Homo sapiens]                      311   2e-85
gi|4885375 histone cluster 1, H1c [Homo sapiens]                      299   1e-81
gi|4885373 histone cluster 1, H1a [Homo sapiens]                      253   1e-67
gi|20544168 histone cluster 1, H1t [Homo sapiens]                     173   9e-44
gi|4885371 H1 histone family, member 0 [Homo sapiens]                 114   5e-26
gi|5174449 H1 histone family, member X [Homo sapiens]                  96   3e-20
gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens]     77   1e-14
gi|24475863 H1 histone family, member O, oocyte-specific [Homo s...    71   9e-13
gi|32401437 H1 histone family, member N, testis-specific [Homo s...    64   1e-10
gi|111548666 SNF2 histone linker PHD RING helicase isoform a [Ho...    59   3e-09
gi|27436873 SNF2 histone linker PHD RING helicase isoform b [Hom...    59   3e-09
gi|55743106 alpha 3 type VI collagen isoform 5 precursor [Homo s...    54   1e-07
gi|55743098 alpha 3 type VI collagen isoform 1 precursor [Homo s...    54   1e-07
gi|240255535 alpha 3 type VI collagen isoform 4 precursor [Homo ...    54   1e-07
gi|239758013 PREDICTED: hypothetical protein [Homo sapiens]            54   1e-07
gi|153070260 myristoylated alanine-rich protein kinase C substra...    54   1e-07
gi|78000183 ribosomal protein L14 [Homo sapiens]                       51   7e-07
gi|78000181 ribosomal protein L14 [Homo sapiens]                       51   7e-07
gi|53692189 adipocyte enhancer binding protein 1 precursor [Homo...    51   9e-07
gi|153945728 microtubule-associated protein 1B [Homo sapiens]          50   2e-06
gi|239758117 PREDICTED: hypothetical protein [Homo sapiens]            49   3e-06
gi|104526627 triadin [Homo sapiens]                                    49   3e-06
gi|56676330 HP1-BP74 [Homo sapiens]                                    49   3e-06
gi|239753329 PREDICTED: hypothetical protein XP_002345623 [Homo ...    49   5e-06
gi|150170670 piccolo isoform 2 [Homo sapiens]                          48   6e-06
gi|150378539 piccolo isoform 1 [Homo sapiens]                          48   6e-06
gi|29244924 chromodomain helicase DNA binding protein 6 [Homo sa...    48   6e-06
gi|153791662 coiled-coil domain containing 71 [Homo sapiens]           48   8e-06

>gi|4885381 histone cluster 1, H1b [Homo sapiens]
          Length = 226

 Score =  427 bits (1097), Expect = e-120
 Identities = 226/226 (100%), Positives = 226/226 (100%)

Query: 1   MSETAPAETATPAPVEKSPAKKKATKKAAGAGAAKRKATGPPVSELITKAVAASKERNGL 60
           MSETAPAETATPAPVEKSPAKKKATKKAAGAGAAKRKATGPPVSELITKAVAASKERNGL
Sbjct: 1   MSETAPAETATPAPVEKSPAKKKATKKAAGAGAAKRKATGPPVSELITKAVAASKERNGL 60

Query: 61  SLAALKKALAAGGYDVEKNNSRIKLGLKSLVSKGTLVQTKGTGASGSFKLNKKAASGEAK 120
           SLAALKKALAAGGYDVEKNNSRIKLGLKSLVSKGTLVQTKGTGASGSFKLNKKAASGEAK
Sbjct: 61  SLAALKKALAAGGYDVEKNNSRIKLGLKSLVSKGTLVQTKGTGASGSFKLNKKAASGEAK 120

Query: 121 PKAKKAGAAKAKKPAGATPKKAKKAAGAKKAVKKTPKKAKKPAAAGVKKVAKSPKKAKAA 180
           PKAKKAGAAKAKKPAGATPKKAKKAAGAKKAVKKTPKKAKKPAAAGVKKVAKSPKKAKAA
Sbjct: 121 PKAKKAGAAKAKKPAGATPKKAKKAAGAKKAVKKTPKKAKKPAAAGVKKVAKSPKKAKAA 180

Query: 181 AKPKKATKSPAKPKAVKPKAAKPKAAKPKAAKPKAAKAKKAAAKKK 226
           AKPKKATKSPAKPKAVKPKAAKPKAAKPKAAKPKAAKAKKAAAKKK
Sbjct: 181 AKPKKATKSPAKPKAVKPKAAKPKAAKPKAAKPKAAKAKKAAAKKK 226


>gi|4885379 histone cluster 1, H1e [Homo sapiens]
          Length = 219

 Score =  337 bits (864), Expect = 5e-93
 Identities = 188/222 (84%), Positives = 193/222 (86%), Gaps = 6/222 (2%)

Query: 1   MSETAPAETATPAPVEKSPAKKKATKKAAGAGAAKRKATGPPVSELITKAVAASKERNGL 60
           MSETAPA  A PAP EK+P KKKA K A   GAAKRKA+GPPVSELITKAVAASKER+G+
Sbjct: 1   MSETAPAAPAAPAPAEKTPVKKKARKSA---GAAKRKASGPPVSELITKAVAASKERSGV 57

Query: 61  SLAALKKALAAGGYDVEKNNSRIKLGLKSLVSKGTLVQTKGTGASGSFKLNKKAASGEAK 120
           SLAALKKALAA GYDVEKNNSRIKLGLKSLVSKGTLVQTKGTGASGSFKLNKKAASGEAK
Sbjct: 58  SLAALKKALAAAGYDVEKNNSRIKLGLKSLVSKGTLVQTKGTGASGSFKLNKKAASGEAK 117

Query: 121 PKAKKAGAAKAKKPAGAT--PKKAKKAAGAKKAVKKTPKKAKKPAAAGVKKVAKSPKKAK 178
           PKAKKAGAAKAKKPAGA   PKKA  AA  KK+ KKTPKKAKKPAAA   K AKSPKKAK
Sbjct: 118 PKAKKAGAAKAKKPAGAAKKPKKATGAATPKKSAKKTPKKAKKPAAAAGAKKAKSPKKAK 177

Query: 179 AAAKPKKATKSPAKPKAVKPKAAKPKAAKPKAAKPKAAKAKK 220
            AAKPKKA KSPAK KAVKPKAAKPK AKPKAAKPK A AKK
Sbjct: 178 -AAKPKKAPKSPAKAKAVKPKAAKPKTAKPKAAKPKKAAAKK 218


>gi|4885377 histone cluster 1, H1d [Homo sapiens]
          Length = 221

 Score =  311 bits (798), Expect = 2e-85
 Identities = 179/230 (77%), Positives = 188/230 (81%), Gaps = 13/230 (5%)

Query: 1   MSETAPAETATPAPVEKSPAKKKATKKAAGAGAAKRKATGPPVSELITKAVAASKERNGL 60
           MSETAP     PAP EK+P KKKA K  AGA A KRKA+GPPVSELITKAVAASKER+G+
Sbjct: 1   MSETAPLAPTIPAPAEKTPVKKKAKK--AGATAGKRKASGPPVSELITKAVAASKERSGV 58

Query: 61  SLAALKKALAAGGYDVEKNNSRIKLGLKSLVSKGTLVQTKGTGASGSFKLNKKAASGEAK 120
           SLAALKKALAA GYDVEKNNSRIKLGLKSLVSKGTLVQTKGTGASGSFKLNKKAASGE K
Sbjct: 59  SLAALKKALAAAGYDVEKNNSRIKLGLKSLVSKGTLVQTKGTGASGSFKLNKKAASGEGK 118

Query: 121 PKAKKAGAAKAKKPAGATPKKAKKAAGA---KKAVKKTPKKAKKPA-AAGVKKVAKSPKK 176
           PKAKKAGAAK +KPAGA  KK KK AGA   KK++KKTPKK KKPA AAG KKVAKS KK
Sbjct: 119 PKAKKAGAAKPRKPAGAA-KKPKKVAGAATPKKSIKKTPKKVKKPATAAGTKKVAKSAKK 177

Query: 177 AKAAAKPKKATKSPAKPKAVKPKAAKPKAAKPKAAKPKAAKAKKAAAKKK 226
            K   +PKKA KSPA     K KA KPKAAKPK+ KPK  KAKKAA KKK
Sbjct: 178 VK-TPQPKKAAKSPA-----KAKAPKPKAAKPKSGKPKVTKAKKAAPKKK 221


>gi|4885375 histone cluster 1, H1c [Homo sapiens]
          Length = 213

 Score =  299 bits (765), Expect = 1e-81
 Identities = 171/217 (78%), Positives = 176/217 (81%), Gaps = 9/217 (4%)

Query: 1   MSETAPAETATPAPVEKSPAKKKATKKAAGAGAAKRKATGPPVSELITKAVAASKERNGL 60
           MSETAPA  A   P EK+P KKKA KKA G     RKA+GPPVSELITKAVAASKER+G+
Sbjct: 1   MSETAPAAPAAAPPAEKAPVKKKAAKKAGGT---PRKASGPPVSELITKAVAASKERSGV 57

Query: 61  SLAALKKALAAGGYDVEKNNSRIKLGLKSLVSKGTLVQTKGTGASGSFKLNKKAASGEAK 120
           SLAALKKALAA GYDVEKNNSRIKLGLKSLVSKGTLVQTKGTGASGSFKLNKKAASGEAK
Sbjct: 58  SLAALKKALAAAGYDVEKNNSRIKLGLKSLVSKGTLVQTKGTGASGSFKLNKKAASGEAK 117

Query: 121 PKAKKAGAAKAKKPAGATPKKAKKAAGA--KKAVKKTPKKAKKPAAAGV-KKVAKSPKKA 177
           PK KKAG  K KKP GA  K  K A GA  KK+ KKTPKKAKKPAAA V KKVAKSPKKA
Sbjct: 118 PKVKKAGGTKPKKPVGAAKKPKKAAGGATPKKSAKKTPKKAKKPAAATVTKKVAKSPKKA 177

Query: 178 KAAAKPKKATKSPAKPKAVKPKAAKPKAAKPKAAKPK 214
           K  AKPKKA KS A  KAVKPKAAKPK  KPK A PK
Sbjct: 178 K-VAKPKKAAKSAA--KAVKPKAAKPKVVKPKKAAPK 211


>gi|4885373 histone cluster 1, H1a [Homo sapiens]
          Length = 215

 Score =  253 bits (645), Expect = 1e-67
 Identities = 147/220 (66%), Positives = 160/220 (72%), Gaps = 6/220 (2%)

Query: 1   MSETAPAETATPAPVEKSPAKKKATKKAAGAGAAKRKATGPPVSELITKAVAASKERNGL 60
           MSET P   A  A  EK  A KKA K A  A A+K+K  GP VSELI +A ++SKER G+
Sbjct: 1   MSETVPPAPAASAAPEKPLAGKKAKKPAKAAAASKKKPAGPSVSELIVQAASSSKERGGV 60

Query: 61  SLAALKKALAAGGYDVEKNNSRIKLGLKSLVSKGTLVQTKGTGASGSFKLNKKAASGEAK 120
           SLAALKKALAA GYDVEKNNSRIKLG+KSLVSKGTLVQTKGTGASGSFKLNKKA+S E K
Sbjct: 61  SLAALKKALAAAGYDVEKNNSRIKLGIKSLVSKGTLVQTKGTGASGSFKLNKKASSVETK 120

Query: 121 PKAKKAGAAKAKKPAGATPKKAKKAAGAKKAVKKTPKKAKKPAAAGVKKVAKSPKKAKAA 180
           P A K   A   K  GA+ KK KKA GA K   KTPKKAKKPAA   +K +K+PKK K  
Sbjct: 121 PGASK--VATKTKATGAS-KKLKKATGASKKSVKTPKKAKKPAA--TRKSSKNPKKPK-T 174

Query: 181 AKPKKATKSPAKPKAVKPKAAKPKAAKPKAAKPKAAKAKK 220
            KPKK  KSPAK KAVKPKAAK +  KPK AKPK A  KK
Sbjct: 175 VKPKKVAKSPAKAKAVKPKAAKARVTKPKTAKPKKAAPKK 214


>gi|20544168 histone cluster 1, H1t [Homo sapiens]
          Length = 207

 Score =  173 bits (439), Expect = 9e-44
 Identities = 111/216 (51%), Positives = 138/216 (63%), Gaps = 12/216 (5%)

Query: 1   MSETAPAETATP--APVEKSPAKKKATKKAAGAGAAKRKATGPPVSELITKAVAASKERN 58
           MSET PA +A+   A +EK P KK+  +K AG  +A RK     VS+LIT+A++ S+ER 
Sbjct: 1   MSETVPAASASAGVAAMEKLPTKKRG-RKPAGLISASRKVPNLSVSKLITEALSVSQERV 59

Query: 59  GLSLAALKKALAAGGYDVEKNNSRIKLGLKSLVSKGTLVQTKGTGASGSFKLNKKAASGE 118
           G+SL ALKKALAA GYDVEKNNSRIKL LKSLV+KG LVQT+GTGASGSFKL+KK     
Sbjct: 60  GMSLVALKKALAAAGYDVEKNNSRIKLSLKSLVNKGILVQTRGTGASGSFKLSKKVIPKS 119

Query: 119 AKPKAKKAGAAKAKKPAGATPKKAKKAAGAKKAVKKTPKKAKKPAAAGVKKVAKSPKKAK 178
            + KAKK+ +AK KK   +   K+ K A       KT K+AKKP A    K  +S +KAK
Sbjct: 120 TRSKAKKSVSAKTKKLVLSRDSKSPKTA-------KTNKRAKKPRAT-TPKTVRSGRKAK 171

Query: 179 AAAKPKKATKSPAKPKAVKPKAAKPKAAKPKAAKPK 214
             AK K+  KSP K +A K K  +      + A  K
Sbjct: 172 -GAKGKQQQKSPVKARASKSKLTQHHEVNVRKATSK 206


>gi|4885371 H1 histone family, member 0 [Homo sapiens]
          Length = 194

 Score =  114 bits (286), Expect = 5e-26
 Identities = 90/228 (39%), Positives = 111/228 (48%), Gaps = 45/228 (19%)

Query: 8   ETATPAPVEKSPAKKKATKKAAGAGAAKRKATGPPVSELITKAVAASKERNGLSLAALKK 67
           E +T AP  K P + KA+KK+            P  S++I  A+ A K R G S  +++K
Sbjct: 3   ENSTSAPAAK-PKRAKASKKSTDH---------PKYSDMIVAAIQAEKNRAGSSRQSIQK 52

Query: 68  ALAAGGYDVEKNNSRIKLGLKSLVSKGTLVQTKGTGASGSFKLNKKAASGEAKPKAKKAG 127
            + +     E  +S+IKL +K LV+ G L QTKG GASGSF+L K               
Sbjct: 53  YIKSHYKVGENADSQIKLSIKRLVTTGVLKQTKGVGASGSFRLAKSDE------------ 100

Query: 128 AAKAKKPAGATPKKAKKAAGAKKAVKK--TPKKAKKPAAAGVKKVAKSPK-------KAK 178
                      PKK+      KK +KK  TPKKA KP  A  K   K PK       K K
Sbjct: 101 -----------PKKSVAFKKTKKEIKKVATPKKASKPKKAASKAPTKKPKATPVKKAKKK 149

Query: 179 AAAKPKKATKSPAKPKAVKPKAAKPKAAKPKAAKPKAAKAKKAAAKKK 226
            AA PKKA K P   KA   KA+KPK AKP   KPKA  + K A KKK
Sbjct: 150 LAATPKKA-KKPKTVKAKPVKASKPKKAKP--VKPKAKSSAKRAGKKK 194


>gi|5174449 H1 histone family, member X [Homo sapiens]
          Length = 213

 Score = 95.5 bits (236), Expect = 3e-20
 Identities = 72/211 (34%), Positives = 99/211 (46%), Gaps = 14/211 (6%)

Query: 8   ETATPAPVEKSPAKKKATKKAAGAGA---------AKRKATGPPVSELITKAVAASKERN 58
           E A P    +  AKK    KA G+ A         +K+K      S+L+ + +    ERN
Sbjct: 6   EEALPVTTAEGMAKK--VTKAGGSAALSPSKKRKNSKKKNQPGKYSQLVVETIRRLGERN 63

Query: 59  GLSLAAL-KKALAAGGYDVEKNNSRIKLGLKSLVSKGTLVQTKGTGASGSFKLNKKAASG 117
           G SLA +  +A     +D +   + +K  +K+LV   TL+Q KGTGA+GSFKLN+K   G
Sbjct: 64  GSSLAKIYTEAKKVPWFDQQNGRTYLKYSIKALVQNDTLLQVKGTGANGSFKLNRKKLEG 123

Query: 118 EAKPKAKKAGAAKAKKPAGATPKKAKKAAGAKKAVKKTPKKAKKPAAAGVKKVAKSPKKA 177
             + +   A A      A    K A  AAG+++A KK P + +KP     KK A + K  
Sbjct: 124 GGERRGAPAAATAPAPTAHKAKKAAPGAAGSRRADKK-PARGQKPEQRSHKKGAGAKKDK 182

Query: 178 KAAAKPKKATKSPAKPKAVKPKAAK-PKAAK 207
              AK   A       KA KP   K PK  K
Sbjct: 183 GGKAKKTAAAGGKKVKKAAKPSVPKVPKGRK 213



 Score = 33.9 bits (76), Expect = 0.12
 Identities = 29/76 (38%), Positives = 35/76 (46%), Gaps = 8/76 (10%)

Query: 5   APAETATPAPVEKSPAKKKATKKAAGAGAA-KRKATG-PPVSELITKAVAASKERNGLSL 62
           APA    PAP       KKA   AAG+  A K+ A G  P      K   A K++ G + 
Sbjct: 130 APAAATAPAPTAHKA--KKAAPGAAGSRRADKKPARGQKPEQRSHKKGAGAKKDKGGKA- 186

Query: 63  AALKKALAAGGYDVEK 78
              KK  AAGG  V+K
Sbjct: 187 ---KKTAAAGGKKVKK 199


>gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens]
          Length = 1020

 Score = 77.0 bits (188), Expect = 1e-14
 Identities = 70/224 (31%), Positives = 101/224 (45%), Gaps = 13/224 (5%)

Query: 5   APAETATPAPVEKSPAKKKATKKAAGAGAAKRKATGPPVSELITKAVAASKERNGLSLAA 64
           +PAE  +P    KSPAK++A          K +A  P   +   KA + +KE       A
Sbjct: 540 SPAEVKSPEKA-KSPAKEEAKSPPEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPAEA 598

Query: 65  LKKALAAGGYDVE-KNNSRIKLGLKSLVSKGTLVQTKGTGASGSFKLNKKAASGEAKPKA 123
                A      E K+ +  K  +K        V++     S + +  K     ++  K 
Sbjct: 599 KSPEKAKSPVKEEAKSPAEAKSPVKEEAKSPAEVKSPEKAKSPTKEEAKSPEKAKSPEKE 658

Query: 124 KKAGAAKAKKPAGATPKKAKKAAGAKKAVKKTPKKAKKPAAAGVKKVAKSPKKAKAAAK- 182
           +     KAK P  A  K  +KA    KA  K+P+KAK P    VK+ AKSP+KAK+  K 
Sbjct: 659 EAKSPEKAKSPVKAEAKSPEKAKSPVKAEAKSPEKAKSP----VKEEAKSPEKAKSPVKE 714

Query: 183 ----PKKATKSPAKPKAVKPKAAKPKAAKPKAAKPKAAKAKKAA 222
               P+KA KSP K +A  P+ AK    K +A  P+ AK+ + A
Sbjct: 715 EAKSPEKA-KSPVKEEAKTPEKAK-SPVKEEAKSPEKAKSPEKA 756



 Score = 71.2 bits (173), Expect = 7e-13
 Identities = 67/234 (28%), Positives = 99/234 (42%), Gaps = 20/234 (8%)

Query: 2   SETAPAE-TATPAPVEKSPAKKKATKKAAGAGAAKRKATGPPVSELITKAVAASKERNGL 60
           +++ PAE  A+P    KSP K++A   A      K +A  P   +   KA + +KE    
Sbjct: 501 TKSPPAEEAASPEKEAKSPVKEEAKSPAEAKSPEKEEAKSPAEVKSPEKAKSPAKEE--- 557

Query: 61  SLAALKKALAAGGYDVEKNNSRIKLGLKSLVSKGTLVQTKGTGASGSFKLNKKAASGEAK 120
                K    A   + E+  S  ++            + K    + S +  K     EAK
Sbjct: 558 ----AKSPPEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPAEAKSPEKAKSPVKEEAK 613

Query: 121 PKAKKAGAAKAKKPAGATPKKAKKAAGAKKAVKKTPKKAKKPAAAGVKKVAKSPKKA--- 177
             A+     K +  + A  K  +KA    K   K+P+KAK P     K+ AKSP+KA   
Sbjct: 614 SPAEAKSPVKEEAKSPAEVKSPEKAKSPTKEEAKSPEKAKSPE----KEEAKSPEKAKSP 669

Query: 178 -KAAAKPKKATKSPAKPKAVKPKAA----KPKAAKPKAAKPKAAKAKKAAAKKK 226
            KA AK  +  KSP K +A  P+ A    K +A  P+ AK    +  K+  K K
Sbjct: 670 VKAEAKSPEKAKSPVKAEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKSPEKAK 723



 Score = 63.2 bits (152), Expect = 2e-10
 Identities = 67/228 (29%), Positives = 95/228 (41%), Gaps = 37/228 (16%)

Query: 5   APAETATPAPVEKSPAKKKATKKAAGAGAAKRKATGPPVSELITKAVAASKERNGLSLAA 64
           +PAE  +P    KSP K++A   A      K +A  P   +   KA + +KE        
Sbjct: 594 SPAEAKSPEKA-KSPVKEEAKSPAEAKSPVKEEAKSPAEVKSPEKAKSPTKEE------- 645

Query: 65  LKKALAAGGYDVEKNNSRIKLGLKSLVSKGTLVQTKGTGASGSFKLNKKAASGEAKPKAK 124
                       EK  S  K   KS     + V+ +           K     ++  KA+
Sbjct: 646 --------AKSPEKAKSPEKEEAKSPEKAKSPVKAEA----------KSPEKAKSPVKAE 687

Query: 125 KAGAAKAKKPAGATPKKAKKAAGAKKAVKKTPKKAKKPAAAGVKKVAKSPKKAKAAAK-- 182
                KAK P     K  +KA    K   K+P+KAK P    VK+ AK+P+KAK+  K  
Sbjct: 688 AKSPEKAKSPVKEEAKSPEKAKSPVKEEAKSPEKAKSP----VKEEAKTPEKAKSPVKEE 743

Query: 183 ---PKKATKSPAKPKAVKPKAAKPKA-AKPKAAKPKAAKAKKAAAKKK 226
              P+KA KSP K K +  K+ + K  AK +A  P     +KA +  K
Sbjct: 744 AKSPEKA-KSPEKAKTLDVKSPEAKTPAKEEARSPADKFPEKAKSPVK 790



 Score = 62.0 bits (149), Expect = 4e-10
 Identities = 65/235 (27%), Positives = 93/235 (39%), Gaps = 14/235 (5%)

Query: 5   APAETATPAPVE-KSPAKKKATKKAAGAGAAKRKATGPPVSELITKAVAASKERNGLSLA 63
           +P +  +P   E KSP K K+  KA      K K+     ++   KA +  KE    S  
Sbjct: 662 SPEKAKSPVKAEAKSPEKAKSPVKAEAKSPEKAKSPVKEEAKSPEKAKSPVKEE-AKSPE 720

Query: 64  ALKKALAAGGYDVEKNNSRIKLGLKS-----LVSKGTLVQTKGTGASGSFKLNKKAASGE 118
             K  +       EK  S +K   KS        K   +  K   A    K   ++ + +
Sbjct: 721 KAKSPVKEEAKTPEKAKSPVKEEAKSPEKAKSPEKAKTLDVKSPEAKTPAKEEARSPADK 780

Query: 119 AKPKAKKA------GAAKAKKPAGATPKKAKKAAGAKKAVKKTPKKAKKPAAAGVKKVAK 172
              KAK           KAK P     K  +K    K+ VK   K+ +KP    VK+  K
Sbjct: 781 FPEKAKSPVKEEVKSPEKAKSPLKEDAKAPEKEIPKKEEVKSPVKEEEKPQEVKVKEPPK 840

Query: 173 SPKKAKAAAKPK-KATKSPAKPKAVKPKAAKPKAAKPKAAKPKAAKAKKAAAKKK 226
             ++ KA A PK +  K   K +A K +A KPK  + K    +  K  K  AKK+
Sbjct: 841 KAEEEKAPATPKTEEKKDSKKEEAPKKEAPKPKVEEKKEPAVEKPKESKVEAKKE 895



 Score = 52.4 bits (124), Expect = 3e-07
 Identities = 70/243 (28%), Positives = 98/243 (40%), Gaps = 27/243 (11%)

Query: 6   PAETATPAPVE-KSPAKKKATKKAAGAGAAKRKATGP-------PVSELITKAVAASKER 57
           P +  +P   E KSP K K+ +KA        +A  P       P  +   KA +  KE 
Sbjct: 733 PEKAKSPVKEEAKSPEKAKSPEKAKTLDVKSPEAKTPAKEEARSPADKFPEKAKSPVKEE 792

Query: 58  ---NGLSLAALKKALAAGGYDVEKNNSRIKLGLKSLVSKGTLVQTKGTGASGSFKLNKKA 114
                 + + LK+   A   ++ K    +K  +K    K   V+ K        +     
Sbjct: 793 VKSPEKAKSPLKEDAKAPEKEIPKKEE-VKSPVKE-EEKPQEVKVKEPPKKAEEEKAPAT 850

Query: 115 ASGEAKPKAKKAGAAKAKKPAGATPKKAKKAAGAKKAVKKTPKKAKKPAAAGVKKVAKSP 174
              E K  +KK  A K + P    PK  +K   A +  K++  +AKK  A   KKV    
Sbjct: 851 PKTEEKKDSKKEEAPKKEAPK---PKVEEKKEPAVEKPKESKVEAKKEEAEDKKKVPTPE 907

Query: 175 KKA------KAAAKPKKAT----KSPAKPKAVKP-KAAKPKAAKPKAAKPKAAKAKKAAA 223
           K+A      K  AKPK+ T    K P   KA +P K A+ K A P+    K  KAKK   
Sbjct: 908 KEAPAKVEVKEDAKPKEKTEVAKKEPDDAKAKEPSKPAEKKEAAPEKKDTKEEKAKKPEE 967

Query: 224 KKK 226
           K K
Sbjct: 968 KPK 970



 Score = 50.8 bits (120), Expect = 9e-07
 Identities = 69/243 (28%), Positives = 96/243 (39%), Gaps = 26/243 (10%)

Query: 6    PAETATPAPVE-KSPAKKKAT----KKAAGAGAAKRKATGPPVSELITKAVAASKERNGL 60
            P +  +P   E KSP K K+      KA      K++    PV E   +     K +   
Sbjct: 782  PEKAKSPVKEEVKSPEKAKSPLKEDAKAPEKEIPKKEEVKSPVKE--EEKPQEVKVKEPP 839

Query: 61   SLAALKKALAAGGYDVEKNNSRIKLGLKSLVSKGTLVQTKGTGASGSFKLNKKAASGEAK 120
              A  +KA A    + EK +S+ +   K    K  + + K        +   +A   EA+
Sbjct: 840  KKAEEEKAPATPKTE-EKKDSKKEEAPKKEAPKPKVEEKKEPAVEKPKESKVEAKKEEAE 898

Query: 121  PKAK-----KAGAAKAKKPAGATPKK----AKKAAGAKKAVKKTPKKAKKPAAAGVKKVA 171
             K K     K   AK +    A PK+    AKK     KA K+  K A+K  AA  KK  
Sbjct: 899  DKKKVPTPEKEAPAKVEVKEDAKPKEKTEVAKKEPDDAKA-KEPSKPAEKKEAAPEKKDT 957

Query: 172  KSPKKAKAAAKPKKATKSPAKPKAVKPKAAKPKAAK--------PKAAKPKAAKAKKAAA 223
            K  K  K   KPK   K+    K +  + +KPKA K         K +KP     +  AA
Sbjct: 958  KEEKAKKPEEKPKTEAKAKEDDKTLSKEPSKPKAEKAEKSSSTDQKDSKPPEKATEDKAA 1017

Query: 224  KKK 226
            K K
Sbjct: 1018 KGK 1020



 Score = 45.8 bits (107), Expect = 3e-05
 Identities = 40/119 (33%), Positives = 62/119 (52%), Gaps = 15/119 (12%)

Query: 112 KKAASGEAKPKAKKAGAAKAKKPAGATPKKAKKAAGAKKAVKKTPKKAKKPAAAGVKKVA 171
           ++A  GE + K+  A  A       A+P+K  K+   ++A  K+P +AK P     K  A
Sbjct: 492 EEAEGGEEETKSPPAEEA-------ASPEKEAKSPVKEEA--KSPAEAKSPEKEEAKSPA 542

Query: 172 --KSPKKAKAAAKPKKATKSPAKPKAVKPKAAKPKA--AKPKAAKPKAAKAKKAAAKKK 226
             KSP+KAK+ A  K+  KSP + K+ + + AK  A    P+ AK  A +  K+ A+ K
Sbjct: 543 EVKSPEKAKSPA--KEEAKSPPEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPAEAK 599



 Score = 44.7 bits (104), Expect = 7e-05
 Identities = 48/159 (30%), Positives = 83/159 (52%), Gaps = 16/159 (10%)

Query: 78  KNNSRIKLGLKSLVSKGTLV---QTKGTGASGSFKLNKKAASGEAKPKAKKAGA---AKA 131
           K+  +IK+  KS   K T++   QT+ T  +      ++  + E + K ++ G    A+ 
Sbjct: 439 KSEEKIKVVEKS--EKETVIVEEQTEETQVTEEVTEEEEKEAKEEEGKEEEGGEEEEAEG 496

Query: 132 KKPAGATPKKAKKAAGAKKAVKKTPKKAKKPAAAGV--KKVAKSPKKAKAAAKPKKATKS 189
            +    +P   + A+  K+A     ++AK PA A    K+ AKSP + K+   P+KA KS
Sbjct: 497 GEEETKSPPAEEAASPEKEAKSPVKEEAKSPAEAKSPEKEEAKSPAEVKS---PEKA-KS 552

Query: 190 PAKPKAVKPKAAK-PKAAKPKA-AKPKAAKAKKAAAKKK 226
           PAK +A  P  AK P+  + K+ A+ K+ +  K+ AK++
Sbjct: 553 PAKEEAKSPPEAKSPEKEEAKSPAEVKSPEKAKSPAKEE 591


>gi|24475863 H1 histone family, member O, oocyte-specific [Homo
           sapiens]
          Length = 346

 Score = 70.9 bits (172), Expect = 9e-13
 Identities = 77/275 (28%), Positives = 119/275 (43%), Gaps = 51/275 (18%)

Query: 2   SETAPAETATPAPVEKSPAKKKATKKAAGAGAAKRKATG-------PPVSELITKAVAAS 54
           S+ +P+ T+T A   +SP  +K      G        +        PPV  ++ +A+ A 
Sbjct: 8   SDISPSSTST-AGSSRSPESEKPGPSHGGVPPGGPSHSSLPVGRRHPPVLRMVLEALQAG 66

Query: 55  KERNGLSLAALKKALAAG--GYDVEKNNSRIKLGLKSLVSKGTLVQ---TKGTGASGSFK 109
           ++R G S+AA+K  +       DV +    +K  L + + +G L +   +K  GA+GSFK
Sbjct: 67  EQRRGTSVAAIKLYILHKYPTVDVLRFKYLLKQALATGMRRGLLARPLNSKARGATGSFK 126

Query: 110 L---------NKKAASGEAKPKAKKAGAAKAKKPAGATPK-----KAKKAAGAKKAVKKT 155
           L          +K A   A  +A +A     KKP+ A        K KKAA     V+K 
Sbjct: 127 LVPKHKKKIQPRKMAPATAPRRAGEAKGKGPKKPSEAKEDPPNVGKVKKAAKRPAKVQKP 186

Query: 156 P-------KKAKKPAAAGVKKVAKSPKKAKAAAKPKKATKSPAKPKAVKPKAA------- 201
           P       +KA+K   A     A+S +  K   KP KA ++P+    +  KA        
Sbjct: 187 PPKPGAATEKARKQGGAAKDTRAQSGEARKVPPKPDKAMRAPSSAGGLSRKAKAKGSRSS 246

Query: 202 -------KPKAAKPKAAKPKAAKAKKAAA---KKK 226
                  +   A+ K++KP A+K K  AA   KKK
Sbjct: 247 QGDAEAYRKTKAESKSSKPTASKVKNGAASPTKKK 281



 Score = 47.0 bits (110), Expect = 1e-05
 Identities = 46/153 (30%), Positives = 66/153 (43%), Gaps = 29/153 (18%)

Query: 99  TKGTGASGSFKLNKKAASGEAK---PKAKKAGAAKAKKPAGATPKKAK-----KAAGAKK 150
           T+     G    + +A SGEA+   PK  KA   +A   AG   +KAK      + G  +
Sbjct: 194 TEKARKQGGAAKDTRAQSGEARKVPPKPDKA--MRAPSSAGGLSRKAKAKGSRSSQGDAE 251

Query: 151 AVKKTPKKAK--KPAAAGVKKVAKSPKKAKAAAK----------------PKKATKSPAK 192
           A +KT  ++K  KP A+ VK  A SP K K  AK                P K + S   
Sbjct: 252 AYRKTKAESKSSKPTASKVKNGAASPTKKKVVAKAKAPKAGQGPNTKAAAPAKGSGSKVV 311

Query: 193 PKAVKPKAAKPKAAKPKAAKPKAAKAKKAAAKK 225
           P  +  K   PK  + KA  P  A + K ++++
Sbjct: 312 PAHLSRKTEAPKGPR-KAGLPIKASSSKVSSQR 343



 Score = 41.2 bits (95), Expect = 7e-04
 Identities = 52/180 (28%), Positives = 70/180 (38%), Gaps = 23/180 (12%)

Query: 12  PAPVEKSPAKKKAT----KKAAGAGAAKRKATG-----PPVSELITKAVAASKERNGLSL 62
           PA V+K P K  A     +K  GA    R  +G     PP  +   KA+ A     GLS 
Sbjct: 180 PAKVQKPPPKPGAATEKARKQGGAAKDTRAQSGEARKVPPKPD---KAMRAPSSAGGLSR 236

Query: 63  AALKKALAAGGYDVEKNNSRIKLGLKSLVSKGTLVQTKGTGASGSFKLNKKAASGEAKPK 122
            A  K   +   D E      K   +S  SK T  + K   AS +    KK  +    PK
Sbjct: 237 KAKAKGSRSSQGDAEAYR---KTKAESKSSKPTASKVKNGAASPT---KKKVVAKAKAPK 290

Query: 123 AKKAGAAKAKKPAGATPKKAKKAAGAKKAVKKTPKKAKKPAAAGVKKVAKSPKKAKAAAK 182
           A +    KA  PA  +  K   A  ++K      +  K P  AG+   A S K +   A+
Sbjct: 291 AGQGPNTKAAAPAKGSGSKVVPAHLSRKT-----EAPKGPRKAGLPIKASSSKVSSQRAE 345



 Score = 33.9 bits (76), Expect = 0.12
 Identities = 54/203 (26%), Positives = 77/203 (37%), Gaps = 13/203 (6%)

Query: 13  APVEKSPAKKKATKKAAGA-------GAAKRKATGPPVSELITKAVAASKERNGLSLAAL 65
           AP     AK K  KK + A       G  K+ A  P   +       A+ E+      A 
Sbjct: 145 APRRAGEAKGKGPKKPSEAKEDPPNVGKVKKAAKRPAKVQKPPPKPGAATEKARKQGGAA 204

Query: 66  KKALAAGGYDVEKNNSRIKLGLKSLVSKGTLVQ-TKGTGASGSFKLNKKAASGEAKPKAK 124
           K   A  G +  K   +    +++  S G L +  K  G+  S    +     +A+ K+ 
Sbjct: 205 KDTRAQSG-EARKVPPKPDKAMRAPSSAGGLSRKAKAKGSRSSQGDAEAYRKTKAESKSS 263

Query: 125 KAGAAKAKKPAGATPKK--AKKAAGAKKAVKKTPKKAKKPAAAGVKKVAKSPKKAKAAAK 182
           K  A+K K  A +  KK    KA  A KA +    KA  PA     KV  +    K  A 
Sbjct: 264 KPTASKVKNGAASPTKKKVVAKAK-APKAGQGPNTKAAAPAKGSGSKVVPAHLSRKTEA- 321

Query: 183 PKKATKSPAKPKAVKPKAAKPKA 205
           PK   K+    KA   K +  +A
Sbjct: 322 PKGPRKAGLPIKASSSKVSSQRA 344


>gi|32401437 H1 histone family, member N, testis-specific [Homo
           sapiens]
          Length = 255

 Score = 63.5 bits (153), Expect = 1e-10
 Identities = 52/204 (25%), Positives = 98/204 (48%), Gaps = 31/204 (15%)

Query: 19  PAKKKATKKAAGAGAAKRKATGPPVSELITKAVAASKERNGLSLAALKKALAAGGYDVEK 78
           PA+K     + G  ++  +     VS+L+ +A++  K   GL+LAALKK L   GY+V +
Sbjct: 41  PAEKTVGGPSRGCSSSVLR-----VSQLVLQAISTHK---GLTLAALKKELRNAGYEVRR 92

Query: 79  NNSRIKLGLKSLVSKGTLVQTKGTGASGSFKLNKKAASGEAKPKAKKAGAAKAKKPAGAT 138
            + R +       +K TL++  G+ A+G F++ K       KP+         +KP  A 
Sbjct: 93  KSGRHEAPRGQ--AKATLLRVSGSDAAGYFRVWK-----VPKPR---------RKPGRAR 136

Query: 139 PKKAKKAAGAKKAVKKTPKKAKKPAAAGVKKVAKSPKKAKAAAKPKKATKSPAKPKAVKP 198
            ++  +A     A  ++ ++ ++P       + K+ +KA+   +     K+ A  +A + 
Sbjct: 137 QEEGTRAPWRTPAAPRSSRRRRQP-------LRKAARKAREVWRRNARAKAKANARARRT 189

Query: 199 KAAKPKAAKPKAAKPKAAKAKKAA 222
           + A+P+A +P  A+ K      AA
Sbjct: 190 RRARPRAKEPPCARAKEEAGATAA 213



 Score = 32.3 bits (72), Expect = 0.34
 Identities = 26/91 (28%), Positives = 42/91 (46%), Gaps = 18/91 (19%)

Query: 104 ASGSFKLNKKAA-SGEAKPKAKKAGAAKAKKPAGATPKKAKKAAGAKKAVKKTPKKAKKP 162
           A    K N +A  +  A+P+AK+   A+AK+ AGAT        G  +AVK+        
Sbjct: 176 ARAKAKANARARRTRRARPRAKEPPCARAKEEAGATAAD----EGRGQAVKE-------- 223

Query: 163 AAAGVKKVAKSPKKAKAAAKPKKATKSPAKP 193
                    +S K  + ++KP++  + P KP
Sbjct: 224 -----DTTPRSGKDKRRSSKPREEKQEPKKP 249


>gi|111548666 SNF2 histone linker PHD RING helicase isoform a [Homo
           sapiens]
          Length = 1687

 Score = 58.9 bits (141), Expect = 3e-09
 Identities = 44/156 (28%), Positives = 70/156 (44%), Gaps = 11/156 (7%)

Query: 35  KRKATGPPVSELITKAVAASKERNGLSLAALKKALAA-GGYDVEKNNSRIKLGLKSLVSK 93
           K K   PP   +I  AV     + G+S+ ++ K +++   YDV++N S +K  LK L+ +
Sbjct: 434 KEKVQCPPTRVMILTAVKEMNGKKGVSILSIYKYVSSIYRYDVQRNRSLLKRMLKCLIFE 493

Query: 94  GTLVQTKGTGASGSFKLNKKAASGEAKPKAKKAGAAKAKKPAGATPKKAKKAAGAKKAVK 153
           G + Q KG G SG+F L K     +   K KK      +K    T K   K   ++    
Sbjct: 494 GLVKQIKGHGFSGTFTLGKNYKEEDICDKTKKQAVGSPRKIQKETRKSGNKDTDSEYLPS 553

Query: 154 KTPK----------KAKKPAAAGVKKVAKSPKKAKA 179
            T            K+++  +   KK+  S KK K+
Sbjct: 554 DTSDDDDDPYYYYYKSRRNRSKLRKKLVPSTKKGKS 589


>gi|27436873 SNF2 histone linker PHD RING helicase isoform b [Homo
           sapiens]
          Length = 1659

 Score = 58.9 bits (141), Expect = 3e-09
 Identities = 44/156 (28%), Positives = 70/156 (44%), Gaps = 11/156 (7%)

Query: 35  KRKATGPPVSELITKAVAASKERNGLSLAALKKALAA-GGYDVEKNNSRIKLGLKSLVSK 93
           K K   PP   +I  AV     + G+S+ ++ K +++   YDV++N S +K  LK L+ +
Sbjct: 434 KEKVQCPPTRVMILTAVKEMNGKKGVSILSIYKYVSSIYRYDVQRNRSLLKRMLKCLIFE 493

Query: 94  GTLVQTKGTGASGSFKLNKKAASGEAKPKAKKAGAAKAKKPAGATPKKAKKAAGAKKAVK 153
           G + Q KG G SG+F L K     +   K KK      +K    T K   K   ++    
Sbjct: 494 GLVKQIKGHGFSGTFTLGKNYKEEDICDKTKKQAVGSPRKIQKETRKSGNKDTDSEYLPS 553

Query: 154 KTPK----------KAKKPAAAGVKKVAKSPKKAKA 179
            T            K+++  +   KK+  S KK K+
Sbjct: 554 DTSDDDDDPYYYYYKSRRNRSKLRKKLVPSTKKGKS 589


>gi|55743106 alpha 3 type VI collagen isoform 5 precursor [Homo
            sapiens]
          Length = 2971

 Score = 53.9 bits (128), Expect = 1e-07
 Identities = 42/98 (42%), Positives = 49/98 (50%), Gaps = 13/98 (13%)

Query: 120  KPKAKKAGAAKAKKPAGATPKKAKKAAGAKKAVKKTPKKAKKPAAAGVKKVAKSPKKAKA 179
            +P  K A A    KPA A P  AK  A     V+  P  A KPA A  K VA  P    A
Sbjct: 2696 QPSVKPAAA----KPAPAKPVAAKPVATKMATVR--PPVAVKPATA-AKPVAAKP----A 2744

Query: 180  AAKPKKATKSPAKPKAVKPKAAKPKAAKPKAAKPKAAK 217
            A +P  A  + AKP A KP+  +P+AAKP A KP   K
Sbjct: 2745 AVRPPAA--AAAKPVATKPEVPRPQAAKPAATKPATTK 2780



 Score = 49.3 bits (116), Expect = 3e-06
 Identities = 37/104 (35%), Positives = 44/104 (42%), Gaps = 21/104 (20%)

Query: 119  AKPKAKKAGAAK--AKKPAGATPKKAKKAAGAKKAVKKTPKKAKKPAAAGVKKVAKSPKK 176
            AKP   K  AAK  A K A   P  A K A A K V   P   + PAAA  K VA     
Sbjct: 2704 AKPAPAKPVAAKPVATKMATVRPPVAVKPATAAKPVAAKPAAVRPPAAAAAKPVA----- 2758

Query: 177  AKAAAKPKKATKSPAKPKAVKPKAAKPKAAKPKAAKPKAAKAKK 220
                           KP+  +P+AAKP A KP   KP    +++
Sbjct: 2759 --------------TKPEVPRPQAAKPAATKPATTKPMVKMSRE 2788



 Score = 44.3 bits (103), Expect = 9e-05
 Identities = 33/108 (30%), Positives = 40/108 (37%), Gaps = 21/108 (19%)

Query: 139  PKKAKKAAGAKKAVKKTPKKAKKPAAAGVKKVAKSPKKA----KAAAKPKKATKSPAKPK 194
            P     +  +       P    KP     K V  + K      + + KP  A  +PAKP 
Sbjct: 2653 PNNVTSSPTSNPVTTTKPVTTTKPVTTTTKPVTTTTKPVTIINQPSVKPAAAKPAPAKPV 2712

Query: 195  AVKP-----------------KAAKPKAAKPKAAKPKAAKAKKAAAKK 225
            A KP                  AAKP AAKP A +P AA A K  A K
Sbjct: 2713 AAKPVATKMATVRPPVAVKPATAAKPVAAKPAAVRPPAAAAAKPVATK 2760



 Score = 43.1 bits (100), Expect = 2e-04
 Identities = 39/99 (39%), Positives = 47/99 (47%), Gaps = 13/99 (13%)

Query: 133  KPAGATPKKAKKAAGAKKAVKKTPKKAKKPAAAGVKKVAKSPKKAKAAAKPKKATKS-PA 191
            KP     + + K A AK A  K    A KP A  +  V     +   A KP  A K   A
Sbjct: 2689 KPVTIINQPSVKPAAAKPAPAKPV--AAKPVATKMATV-----RPPVAVKPATAAKPVAA 2741

Query: 192  KPKAVKP---KAAKPKAAKPKAAKPKAAK--AKKAAAKK 225
            KP AV+P    AAKP A KP+  +P+AAK  A K A  K
Sbjct: 2742 KPAAVRPPAAAAAKPVATKPEVPRPQAAKPAATKPATTK 2780


>gi|55743098 alpha 3 type VI collagen isoform 1 precursor [Homo
            sapiens]
          Length = 3177

 Score = 53.9 bits (128), Expect = 1e-07
 Identities = 42/98 (42%), Positives = 49/98 (50%), Gaps = 13/98 (13%)

Query: 120  KPKAKKAGAAKAKKPAGATPKKAKKAAGAKKAVKKTPKKAKKPAAAGVKKVAKSPKKAKA 179
            +P  K A A    KPA A P  AK  A     V+  P  A KPA A  K VA  P    A
Sbjct: 2902 QPSVKPAAA----KPAPAKPVAAKPVATKMATVR--PPVAVKPATA-AKPVAAKP----A 2950

Query: 180  AAKPKKATKSPAKPKAVKPKAAKPKAAKPKAAKPKAAK 217
            A +P  A  + AKP A KP+  +P+AAKP A KP   K
Sbjct: 2951 AVRPPAA--AAAKPVATKPEVPRPQAAKPAATKPATTK 2986



 Score = 49.3 bits (116), Expect = 3e-06
 Identities = 37/104 (35%), Positives = 44/104 (42%), Gaps = 21/104 (20%)

Query: 119  AKPKAKKAGAAK--AKKPAGATPKKAKKAAGAKKAVKKTPKKAKKPAAAGVKKVAKSPKK 176
            AKP   K  AAK  A K A   P  A K A A K V   P   + PAAA  K VA     
Sbjct: 2910 AKPAPAKPVAAKPVATKMATVRPPVAVKPATAAKPVAAKPAAVRPPAAAAAKPVA----- 2964

Query: 177  AKAAAKPKKATKSPAKPKAVKPKAAKPKAAKPKAAKPKAAKAKK 220
                           KP+  +P+AAKP A KP   KP    +++
Sbjct: 2965 --------------TKPEVPRPQAAKPAATKPATTKPMVKMSRE 2994



 Score = 44.3 bits (103), Expect = 9e-05
 Identities = 33/108 (30%), Positives = 40/108 (37%), Gaps = 21/108 (19%)

Query: 139  PKKAKKAAGAKKAVKKTPKKAKKPAAAGVKKVAKSPKKA----KAAAKPKKATKSPAKPK 194
            P     +  +       P    KP     K V  + K      + + KP  A  +PAKP 
Sbjct: 2859 PNNVTSSPTSNPVTTTKPVTTTKPVTTTTKPVTTTTKPVTIINQPSVKPAAAKPAPAKPV 2918

Query: 195  AVKP-----------------KAAKPKAAKPKAAKPKAAKAKKAAAKK 225
            A KP                  AAKP AAKP A +P AA A K  A K
Sbjct: 2919 AAKPVATKMATVRPPVAVKPATAAKPVAAKPAAVRPPAAAAAKPVATK 2966



 Score = 43.1 bits (100), Expect = 2e-04
 Identities = 39/99 (39%), Positives = 47/99 (47%), Gaps = 13/99 (13%)

Query: 133  KPAGATPKKAKKAAGAKKAVKKTPKKAKKPAAAGVKKVAKSPKKAKAAAKPKKATKS-PA 191
            KP     + + K A AK A  K    A KP A  +  V     +   A KP  A K   A
Sbjct: 2895 KPVTIINQPSVKPAAAKPAPAKPV--AAKPVATKMATV-----RPPVAVKPATAAKPVAA 2947

Query: 192  KPKAVKP---KAAKPKAAKPKAAKPKAAK--AKKAAAKK 225
            KP AV+P    AAKP A KP+  +P+AAK  A K A  K
Sbjct: 2948 KPAAVRPPAAAAAKPVATKPEVPRPQAAKPAATKPATTK 2986


>gi|240255535 alpha 3 type VI collagen isoform 4 precursor [Homo
            sapiens]
          Length = 2570

 Score = 53.9 bits (128), Expect = 1e-07
 Identities = 42/98 (42%), Positives = 49/98 (50%), Gaps = 13/98 (13%)

Query: 120  KPKAKKAGAAKAKKPAGATPKKAKKAAGAKKAVKKTPKKAKKPAAAGVKKVAKSPKKAKA 179
            +P  K A A    KPA A P  AK  A     V+  P  A KPA A  K VA  P    A
Sbjct: 2295 QPSVKPAAA----KPAPAKPVAAKPVATKMATVR--PPVAVKPATA-AKPVAAKP----A 2343

Query: 180  AAKPKKATKSPAKPKAVKPKAAKPKAAKPKAAKPKAAK 217
            A +P  A  + AKP A KP+  +P+AAKP A KP   K
Sbjct: 2344 AVRPPAA--AAAKPVATKPEVPRPQAAKPAATKPATTK 2379



 Score = 49.3 bits (116), Expect = 3e-06
 Identities = 37/104 (35%), Positives = 44/104 (42%), Gaps = 21/104 (20%)

Query: 119  AKPKAKKAGAAK--AKKPAGATPKKAKKAAGAKKAVKKTPKKAKKPAAAGVKKVAKSPKK 176
            AKP   K  AAK  A K A   P  A K A A K V   P   + PAAA  K VA     
Sbjct: 2303 AKPAPAKPVAAKPVATKMATVRPPVAVKPATAAKPVAAKPAAVRPPAAAAAKPVA----- 2357

Query: 177  AKAAAKPKKATKSPAKPKAVKPKAAKPKAAKPKAAKPKAAKAKK 220
                           KP+  +P+AAKP A KP   KP    +++
Sbjct: 2358 --------------TKPEVPRPQAAKPAATKPATTKPMVKMSRE 2387



 Score = 44.3 bits (103), Expect = 9e-05
 Identities = 33/108 (30%), Positives = 40/108 (37%), Gaps = 21/108 (19%)

Query: 139  PKKAKKAAGAKKAVKKTPKKAKKPAAAGVKKVAKSPKKA----KAAAKPKKATKSPAKPK 194
            P     +  +       P    KP     K V  + K      + + KP  A  +PAKP 
Sbjct: 2252 PNNVTSSPTSNPVTTTKPVTTTKPVTTTTKPVTTTTKPVTIINQPSVKPAAAKPAPAKPV 2311

Query: 195  AVKP-----------------KAAKPKAAKPKAAKPKAAKAKKAAAKK 225
            A KP                  AAKP AAKP A +P AA A K  A K
Sbjct: 2312 AAKPVATKMATVRPPVAVKPATAAKPVAAKPAAVRPPAAAAAKPVATK 2359



 Score = 43.1 bits (100), Expect = 2e-04
 Identities = 39/99 (39%), Positives = 47/99 (47%), Gaps = 13/99 (13%)

Query: 133  KPAGATPKKAKKAAGAKKAVKKTPKKAKKPAAAGVKKVAKSPKKAKAAAKPKKATKS-PA 191
            KP     + + K A AK A  K    A KP A  +  V     +   A KP  A K   A
Sbjct: 2288 KPVTIINQPSVKPAAAKPAPAKPV--AAKPVATKMATV-----RPPVAVKPATAAKPVAA 2340

Query: 192  KPKAVKP---KAAKPKAAKPKAAKPKAAK--AKKAAAKK 225
            KP AV+P    AAKP A KP+  +P+AAK  A K A  K
Sbjct: 2341 KPAAVRPPAAAAAKPVATKPEVPRPQAAKPAATKPATTK 2379


>gi|239758013 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 819

 Score = 53.9 bits (128), Expect = 1e-07
 Identities = 65/226 (28%), Positives = 95/226 (42%), Gaps = 50/226 (22%)

Query: 5   APAETATPAPVE-KSPAKKKATKKAAGAGAAKRKATGPPVSELITKAVAASKERNGLSLA 63
           APA +A  A V+      KK  ++ A AG  K +  G        K   A KE       
Sbjct: 39  APALSAAAAGVKILGSGDKKLRRQKAAAGGKKARLRGQ-------KGAVAGKEAR----Q 87

Query: 64  ALKKALAAGGYDVEKNNSR--IKLGLKSLVSKGTLVQTKGTGASGSFKLNKKAASGEAKP 121
             +KA  AGG +      +     G KSL  +G   + +G          K AA+G  KP
Sbjct: 88  HWQKAAGAGGAENRGGGEQKAAAAGTKSLGGRGRKPRRRG---------QKAAATGSKKP 138

Query: 122 K--AKKAGAAKAKKPAGATPKKAKKAAGAKKAVKKTPKKAKKPAAAGVK-KVAKSPKKAK 178
           +  A+K+ AA +K           + AGA+KA           AAAGVK +  + P+KA 
Sbjct: 139 RWRAQKSAAAGSKN----------RGAGAQKAA----------AAAGVKSQGGEKPQKAA 178

Query: 179 AAAKPKKATKSP----AKPKAVKPKAAKPKAAKPKAAKPKAAKAKK 220
           AA    ++ K P    AK +  + K  + + AK +  K +  + KK
Sbjct: 179 AAGAKSRSGKKPRRRGAKSRGDEDKKGRQREAKSRFGKTRGGRRKK 224



 Score = 53.9 bits (128), Expect = 1e-07
 Identities = 64/242 (26%), Positives = 90/242 (37%), Gaps = 40/242 (16%)

Query: 21  KKKATKKAAGAGAAKRKATGPPVSELIT---KAVAASKERNGLSLAALKKALAAGGYDVE 77
           KK    K A  GA  R+  G    +      KA    K R G S     K L   G +  
Sbjct: 223 KKHRRPKPAAGGAKSRRGGGKKPQKQRRRGQKAATGGKSRVGKSRGGGDKKLRRQGQNAA 282

Query: 78  KNNSRIKLGLKSLVSKGTLVQTKGTGASGSFKL---NKKAASGEAKP-----KAKKAGAA 129
              ++     +   + G     KG G  G   L   N +   G  KP     KA KA AA
Sbjct: 283 LAGAK----RRGAATAGEKPAAKGRGGRGPKSLGGQNPRWGRGGKKPRRRGQKATKAAAA 338

Query: 130 KAKKPAGATPKKAKKAAGAKKAVKKTPKKAK--KPAAAGVKKVAKSPKKAKAAAKPK--- 184
             K+  G   K A     ++K  ++  KK +  K +AAG K      KK    AK +   
Sbjct: 339 GTKRGGGGQQKAAVVGVKSRKKQRRRGKKPRRQKASAAGAKSRGGGDKKGLREAKRRGDG 398

Query: 185 -----------KATKSPA---------KPKAVKPKAAKPKAAKPKAAKPKAAKAKKAAAK 224
                      +A K+PA         KP+   PKAAK +  K ++   K  + +   A+
Sbjct: 399 RKKPRWQNPRRRAQKAPAAKPRGGGSKKPRRRGPKAAKSRGGKSRSGGGKKPRRRGQKAR 458

Query: 225 KK 226
           +K
Sbjct: 459 QK 460



 Score = 49.7 bits (117), Expect = 2e-06
 Identities = 59/215 (27%), Positives = 88/215 (40%), Gaps = 27/215 (12%)

Query: 30  GAGAAKRKATGPPVSELITKAVAASKERNGLSLAALKKALAAGGYDVEKNNSRIKLGLKS 89
           G G  K +  G    +  TKA AA  +R G      +KA   G    +K   R K   + 
Sbjct: 319 GRGGKKPRRRG----QKATKAAAAGTKRGG---GGQQKAAVVGVKSRKKQRRRGKKPRRQ 371

Query: 90  LVSKGTLVQTKGTGASGSFKLNKKAASGEAKPK-------AKKAGAAK-----AKKPAGA 137
             S     +++G G     +  K+   G  KP+       A+KA AAK     +KKP   
Sbjct: 372 KASAAG-AKSRGGGDKKGLREAKRRGDGRKKPRWQNPRRRAQKAPAAKPRGGGSKKPRRR 430

Query: 138 TPKKAK------KAAGAKKAVKKTPKKAKKPAAAGVK-KVAKSPKKAKAAAKPKKATKSP 190
            PK AK      ++ G KK  ++  K  +K A AG + +  K   + KA+A   K+    
Sbjct: 431 GPKAAKSRGGKSRSGGGKKPRRRGQKARQKAAEAGAESRGDKKQGRQKASAAGTKSRGGG 490

Query: 191 AKPKAVKPKAAKPKAAKPKAAKPKAAKAKKAAAKK 225
            K  + K    + + A+    K  AA AK    K+
Sbjct: 491 LKSHSGKNLWRRGQKAEAAGEKATAAGAKSRGRKQ 525



 Score = 43.9 bits (102), Expect = 1e-04
 Identities = 57/210 (27%), Positives = 86/210 (40%), Gaps = 24/210 (11%)

Query: 21  KKKATKKAAGAGAAKRKAT---GPPVSELITKAVA--ASKERNGLSLAALKKALAAGGYD 75
           KK   +KAAG GA  RK     G   +    KA A  A+   +G      +K  AAG   
Sbjct: 614 KKAWRQKAAGTGAKSRKKPWRRGQKDAAAAEKAWATGATSRGSGGKQPRWQKPAAAGSES 673

Query: 76  V------EKNNSRIKLGLKSLVSKGTLVQTKGTGASGSFKLNKKAASGEAK----PKAKK 125
                  ++  +R K   +   S+G   Q    G +   +  KK   G+++     K++ 
Sbjct: 674 SAAAAVGQEAEARKKPRRRRAKSRGDGGQNAAVGINPWQRRGKKPRLGKSRGGGGAKSRG 733

Query: 126 AGAAKAKKPAGATPKKAKKAAGAKKAVKKT--PKKAKKPAAAGVKKVAKSPKKAKAAAKP 183
           +G AK++   GA     K  +G K A  K+     AK+    G K  ++S +KA  A   
Sbjct: 734 SGGAKSRGSGGA-----KSRSGKKAAASKSHGGGGAKRRRGGGAK--SRSGEKAVTAGGQ 786

Query: 184 KKATKSPAKPKAVKPKAAKPKAAKPKAAKP 213
           K A     KP  VK +  + + A     KP
Sbjct: 787 KAAAAGGKKPPRVKSRGGRGQKAAAGGKKP 816



 Score = 39.7 bits (91), Expect = 0.002
 Identities = 65/240 (27%), Positives = 89/240 (37%), Gaps = 32/240 (13%)

Query: 6   PAETATPAPVEKSP--AKKKATKKAAGAGAAKRKATGPPVSELITKAVAASKERNGLSLA 63
           P    +  P  + P  AK +  K  +G G   R+       +   KA  A  E  G    
Sbjct: 419 PRGGGSKKPRRRGPKAAKSRGGKSRSGGGKKPRRRG----QKARQKAAEAGAESRGDKKQ 474

Query: 64  ALKKALAAGGYDVEKNNSRIKLGLKSLVSKGTLVQTKGTGASGSFKLNKKAAS-GEAKPK 122
             +KA AAG        SR   GLKS   K    + +   A+G       A S G  +P+
Sbjct: 475 GRQKASAAG------TKSRGG-GLKSHSGKNLWRRGQKAEAAGEKATAAGAKSRGRKQPR 527

Query: 123 AKKAGAAKAKKPAGATPKKAKKAAGAKKAVK--------------KTPKKAKKPAAAGVK 168
            +K   A AK   G +  + ++ A A  A                  P++  + AAA   
Sbjct: 528 RQKPAVAGAKSRVGGSKSRQRQKAVAAGATSHGGGGNKQSRGGGGNKPRQWGQTAAAAKT 587

Query: 169 KVA--KSPKKAKAAAKPKKATKSPAKPKAVKPKAAKPKAAKPKAAKPKAAKAKKAAAKKK 226
           +    K P   KAAA   K+       KA + KAA   A   K  KP     K AAA +K
Sbjct: 588 RGGGDKQPGWQKAAAGVTKSRSGDGGKKAWRQKAAGTGAKSRK--KPWRRGQKDAAAAEK 645



 Score = 39.7 bits (91), Expect = 0.002
 Identities = 55/200 (27%), Positives = 83/200 (41%), Gaps = 17/200 (8%)

Query: 24  ATKKAAGAGAAKRKATGPPVSELITKAVAASKERNGLSLAALK-KALAAGGYDVEKNNSR 82
           A +KA  AGA  R    P   +    AVA +K R G S +  + KA+AAG        ++
Sbjct: 509 AGEKATAAGAKSRGRKQPRRQK---PAVAGAKSRVGGSKSRQRQKAVAAGATSHGGGGNK 565

Query: 83  IKLGLKSLVSKGTLVQTKGTGASGSFKLNKKAASGEAKPKAKKA--GAAKAKKPAGATPK 140
              G       G   +  G  A+ +    K    G+ +P  +KA  G  K++   G    
Sbjct: 566 QSRG-----GGGNKPRQWGQTAAAA----KTRGGGDKQPGWQKAAAGVTKSRSGDGGKKA 616

Query: 141 KAKKAAG-AKKAVKKTPKKAKKPAAAGVKKVAKSPKKAKAAAKPKKATKSPAKPKAVKPK 199
             +KAAG   K+ KK  ++ +K AAA  K  A       +  K  +  K  A        
Sbjct: 617 WRQKAAGTGAKSRKKPWRRGQKDAAAAEKAWATGATSRGSGGKQPRWQKPAAAGSESSAA 676

Query: 200 AAKPKAAKPKAAKPKAAKAK 219
           AA  + A+ +  KP+  +AK
Sbjct: 677 AAVGQEAEAR-KKPRRRRAK 695



 Score = 34.7 bits (78), Expect = 0.068
 Identities = 41/141 (29%), Positives = 53/141 (37%), Gaps = 30/141 (21%)

Query: 115 ASGEAKPKAKKAGAAKAKKPA-----GATPKKAKKAAGAKKAVKKTPKKAKKPAAAGVKK 169
           A+G A P A   GAA A+ P       A P  +  AAG K       K  ++ AAAG KK
Sbjct: 12  AAGRAGPGAP-LGAALARTPVELAAESAAPALSAAAAGVKILGSGDKKLRRQKAAAGGKK 70

Query: 170 VAKSPKKAKAAAK---------------------PKKATKSPAKP---KAVKPKAAKPKA 205
                +K   A K                      +KA  +  K    +  KP+    KA
Sbjct: 71  ARLRGQKGAVAGKEARQHWQKAAGAGGAENRGGGEQKAAAAGTKSLGGRGRKPRRRGQKA 130

Query: 206 AKPKAAKPKAAKAKKAAAKKK 226
           A   + KP+    K AAA  K
Sbjct: 131 AATGSKKPRWRAQKSAAAGSK 151



 Score = 32.3 bits (72), Expect = 0.34
 Identities = 29/124 (23%), Positives = 47/124 (37%), Gaps = 20/124 (16%)

Query: 21  KKKATKKAAGAGAAKRKATGPPVSELITKAVAASKERNGLSLAALKKALAAGGYDVEKNN 80
           KK    K+ G G AK + +G   S    +    +K R+G   AA K     G        
Sbjct: 716 KKPRLGKSRGGGGAKSRGSGGAKS----RGSGGAKSRSGKKAAASKSHGGGGAKRRRGGG 771

Query: 81  SRIKLGLKSLVSKGTLVQTKGTGASGSFKLNKKAASGEAKPKAKKAGAAKAKKPAGATPK 140
           ++ + G K++ + G                 K AA+G  KP   K+   + +K A    K
Sbjct: 772 AKSRSGEKAVTAGG----------------QKAAAAGGKKPPRVKSRGGRGQKAAAGGKK 815

Query: 141 KAKK 144
             ++
Sbjct: 816 PLRR 819


>gi|153070260 myristoylated alanine-rich protein kinase C substrate
           [Homo sapiens]
          Length = 332

 Score = 53.9 bits (128), Expect = 1e-07
 Identities = 60/224 (26%), Positives = 92/224 (41%), Gaps = 12/224 (5%)

Query: 5   APAETATP----APVEKSPAKKKATKKAAGAGAAKRKATGPPVSEL-ITKAVAASKERNG 59
           AP   A+P    AP E   A+  +   A G  A+   +T  P +E   T + +    +  
Sbjct: 95  APEAGASPVEKEAPAEGEAAEPGSPTAAEGEAASAASSTSSPKAEDGATPSPSNETPKKK 154

Query: 60  LSLAALKKALAAGGYDVEKNNSRIKLGLKSLVSKGTLVQTKGTGASGSFKLNKKAASGEA 119
               + KK+    G+  +KN      G ++        + +  G + +      AASGE 
Sbjct: 155 KKRFSFKKSFKLSGFSFKKNKKEAGEGGEAEAPAAEGGKDEAAGGAAAAAAEAGAASGEQ 214

Query: 120 KPKAKKAGAAKAKKPAGATPKKAKKAAGAKKAVKKTPKKAKKPAAAGVKKVAKSPKKAKA 179
                +  AA  +  AG  P++AK    A  A +K P   +  AA    KV +  KKA+ 
Sbjct: 215 AAAPGEEAAAGEEGAAGGDPQEAKPQEAA-VAPEKPPASDETKAAEEPSKVEE--KKAEE 271

Query: 180 AAKPKKATKSPAKPKAVKPKAAKPKAAKPKAAKPKAAKAKKAAA 223
           A     A ++P+   A  P A   + A P A +P AA A  A A
Sbjct: 272 AGASAAACEAPS---AAGPGAPPEQEAAP-AEEPAAAAASSACA 311



 Score = 50.1 bits (118), Expect = 2e-06
 Identities = 70/250 (28%), Positives = 96/250 (38%), Gaps = 38/250 (15%)

Query: 3   ETAPAETATPAPVE-----KSPAKKKATKKAAGAGAAKRKAT--GPPVSELITKAVAASK 55
           + +PA   + A  E      +PA  K    AAG+GAA   A   G P +    +A A+  
Sbjct: 44  DASPAAAESGAKEELQANGSAPAADKEEPAAAGSGAASPSAAEKGEPAAAAAPEAGASPV 103

Query: 56  ERN----------GLSLAALKKALAAG----------GYDVEKNNSRIKLGLKSLVSKGT 95
           E+           G   AA  +A +A           G     +N   K   K    K  
Sbjct: 104 EKEAPAEGEAAEPGSPTAAEGEAASAASSTSSPKAEDGATPSPSNETPKKKKKRFSFK-- 161

Query: 96  LVQTKGTGASG-SFKLNKKAA--SGEAKPKAKKAGAAKAKKPAGATPKKAKKAAGAKKAV 152
               K    SG SFK NKK A   GEA+  A + G  +A   A A   +A  A+G + A 
Sbjct: 162 ----KSFKLSGFSFKKNKKEAGEGGEAEAPAAEGGKDEAAGGAAAAAAEAGAASGEQAAA 217

Query: 153 KKTPKKAKKPAAAGVKKVAKSPKKAKAAAKPKKATKSPAKPKAVKPKAAKPKAAKPKAAK 212
                 A +  AAG       P+  +AA  P+K   S     A +P   + K A+   A 
Sbjct: 218 PGEEAAAGEEGAAGGDPQEAKPQ--EAAVAPEKPPASDETKAAEEPSKVEEKKAEEAGAS 275

Query: 213 PKAAKAKKAA 222
             A +A  AA
Sbjct: 276 AAACEAPSAA 285



 Score = 44.3 bits (103), Expect = 9e-05
 Identities = 33/115 (28%), Positives = 52/115 (45%), Gaps = 6/115 (5%)

Query: 116 SGEAKPKAKKAGAAKAKKPAGATPKKAKKAAGAKKAVKKTPKKAKK--PAAAGVKKVAKS 173
           +G+A P A ++GA +  +  G+ P   K+   A  +   +P  A+K  PAAA   +   S
Sbjct: 42  NGDASPAAAESGAKEELQANGSAPAADKEEPAAAGSGAASPSAAEKGEPAAAAAPEAGAS 101

Query: 174 PKKAKAAAKPKKATKSPAKPKAVKPKAAK--PKAAKPKAAKPKAAKAKKAAAKKK 226
           P + +A A+ + A   P  P A + +AA      + PKA             KKK
Sbjct: 102 PVEKEAPAEGEAA--EPGSPTAAEGEAASAASSTSSPKAEDGATPSPSNETPKKK 154



 Score = 42.0 bits (97), Expect = 4e-04
 Identities = 55/205 (26%), Positives = 78/205 (38%), Gaps = 21/205 (10%)

Query: 10  ATPAPVEKSPAKKKA------TKKAAGAGAAKRKATGPPVSELITKAVAASK-ERNGLSL 62
           ATP+P  ++P KKK       + K +G    K K       E    A    K E  G + 
Sbjct: 142 ATPSPSNETPKKKKKRFSFKKSFKLSGFSFKKNKKEAGEGGEAEAPAAEGGKDEAAGGAA 201

Query: 63  AALKKALAAGGYDVEKNNSRIKLGLKSLVSKGTLVQTKGTGASGSFKLNKKAASGEAKPK 122
           AA  +A AA G            G           +    G        ++AA    KP 
Sbjct: 202 AAAAEAGAASGEQAAAPGEEAAAG-----------EEGAAGGDPQEAKPQEAAVAPEKPP 250

Query: 123 AKKAGAAKAKKPAGATPKKAKKAAGAKKAVKKTPKKAKKPAAAGVKKVAKSPKKAKAAAK 182
           A     A A++P+    KKA++A GA  A  + P  A  P A   ++ A + + A AAA 
Sbjct: 251 ASDETKA-AEEPSKVEEKKAEEA-GASAAACEAPSAAG-PGAPPEQEAAPAEEPAAAAAS 307

Query: 183 PKKATKSPAKPKAVKPKAAKPKAAK 207
              A  S        P+A   +AA+
Sbjct: 308 SACAAPSQEAQPECSPEAPPAEAAE 332



 Score = 33.1 bits (74), Expect = 0.20
 Identities = 40/165 (24%), Positives = 69/165 (41%), Gaps = 21/165 (12%)

Query: 40  GPPVSELITKAVAASKERNGLSLAALKKALAAGGYDVEKNNSRIKLG---LKSLVSKGTL 96
           G   S+   K  AA+ ER G +  A   + A G     + N  +K+      +    G  
Sbjct: 2   GAQFSKTAAKGEAAA-ERPGEAAVASSPSKANG-----QENGHVKVNGDASPAAAESGAK 55

Query: 97  VQTKGTGASGSFKLNKKAASGEAKPKAKKAGAAKAKKP-------AGATPKKAKKAAGAK 149
            + +  G++ +    + AA+G     A    AA+  +P       AGA+P + +  A  +
Sbjct: 56  EELQANGSAPAADKEEPAAAGSG---AASPSAAEKGEPAAAAAPEAGASPVEKEAPAEGE 112

Query: 150 KAVKKTPKKAKKPAAAGVKKVAKSPKKAKAAAKPKKATKSPAKPK 194
            A   +P  A+  AA+     + S  KA+  A P  + ++P K K
Sbjct: 113 AAEPGSPTAAEGEAASAAS--STSSPKAEDGATPSPSNETPKKKK 155



 Score = 33.1 bits (74), Expect = 0.20
 Identities = 35/136 (25%), Positives = 51/136 (37%), Gaps = 9/136 (6%)

Query: 98  QTKGTGASGSFKLNK--KAASGEAKPKAKKAGAAKAKKPAGATPKKAKKAAGAKKAVKKT 155
           Q   T A G     +  +AA   +  KA        K    A+P  A+  A  +     +
Sbjct: 4   QFSKTAAKGEAAAERPGEAAVASSPSKANGQENGHVKVNGDASPAAAESGAKEELQANGS 63

Query: 156 PKKAKKPAAAGVKKVAKSPKKAK-----AAAKPKKATKSPAKPKAVKPKAAKPKAAKPKA 210
              A K   A     A SP  A+     AAA P+       K    + +AA+P    P A
Sbjct: 64  APAADKEEPAAAGSGAASPSAAEKGEPAAAAAPEAGASPVEKEAPAEGEAAEP--GSPTA 121

Query: 211 AKPKAAKAKKAAAKKK 226
           A+ +AA A  + +  K
Sbjct: 122 AEGEAASAASSTSSPK 137


>gi|78000183 ribosomal protein L14 [Homo sapiens]
          Length = 215

 Score = 51.2 bits (121), Expect = 7e-07
 Identities = 36/87 (41%), Positives = 44/87 (50%), Gaps = 1/87 (1%)

Query: 140 KKAKKAAGAKKAVKKTPKKAKKPAAAGVKKVAKSP-KKAKAAAKPKKATKSPAKPKAVKP 198
           KK +KAA  K + KK P      AAA     AK P KK  AA+K   A K PA+    + 
Sbjct: 128 KKLQKAALLKASPKKAPGTKGTAAAAAAAAAAKVPAKKITAASKKAPAQKVPAQKATGQK 187

Query: 199 KAAKPKAAKPKAAKPKAAKAKKAAAKK 225
            A  PKA K + A  + A A KA+ KK
Sbjct: 188 AAPAPKAQKGQKAPAQKAPAPKASGKK 214



 Score = 43.1 bits (100), Expect = 2e-04
 Identities = 38/101 (37%), Positives = 48/101 (47%), Gaps = 6/101 (5%)

Query: 109 KLNKKAASGEAKPKAKKAGAAKA--KKPAGA--TPKKAKKAAGAKKAVKKTPKKAKKPAA 164
           K+  +    E K K +KA   KA  KK  G   T   A  AA AK   KK    +KK  A
Sbjct: 117 KMRNRIIKNEVK-KLQKAALLKASPKKAPGTKGTAAAAAAAAAAKVPAKKITAASKKAPA 175

Query: 165 AGVKKVAKSPKKAKAAAKPKKATKSPAKPKAVKPKAAKPKA 205
             V     + +KA  A K +K  K+PA+ KA  PKA+  KA
Sbjct: 176 QKVPAQKATGQKAAPAPKAQKGQKAPAQ-KAPAPKASGKKA 215



 Score = 38.9 bits (89), Expect = 0.004
 Identities = 41/118 (34%), Positives = 48/118 (40%), Gaps = 10/118 (8%)

Query: 112 KKAASGEAKPKAK---KAGAAKAKKPAGATPKKAKKAAGAKKAVKKTPKKAKKPAAAGVK 168
           KK  + E K K     +    KAKK      K   K       +K +PKKA  P   G  
Sbjct: 93  KKIEARERKAKMTDFDRFKVMKAKKMRNRIIKNEVKKLQKAALLKASPKKA--PGTKGTA 150

Query: 169 KVAKSPKKAKAAAKPKKATKSPAKPKAVKPKAAKPKAAKPKAA-KPKAAKAKKAAAKK 225
             A     A AAAK      + A  KA   K    KA   KAA  PKA K +KA A+K
Sbjct: 151 AAAA----AAAAAKVPAKKITAASKKAPAQKVPAQKATGQKAAPAPKAQKGQKAPAQK 204



 Score = 37.4 bits (85), Expect = 0.011
 Identities = 40/115 (34%), Positives = 46/115 (40%), Gaps = 13/115 (11%)

Query: 125 KAGAAKAKKPAGATPKKAKKAAGAKKAVKKTPKKAKKPAAAGVKKVAK------SPKKAK 178
           K  A +  K   A  +KAK     +  V K  K   +     VKK+ K      SPKKA 
Sbjct: 85  KWAATRWAKKIEARERKAKMTDFDRFKVMKAKKMRNRIIKNEVKKLQKAALLKASPKKAP 144

Query: 179 ------AAAKPKKATKSPAKP-KAVKPKAAKPKAAKPKAAKPKAAKAKKAAAKKK 226
                 AAA    A K PAK   A   KA   K    KA   KAA A KA   +K
Sbjct: 145 GTKGTAAAAAAAAAAKVPAKKITAASKKAPAQKVPAQKATGQKAAPAPKAQKGQK 199


>gi|78000181 ribosomal protein L14 [Homo sapiens]
          Length = 215

 Score = 51.2 bits (121), Expect = 7e-07
 Identities = 36/87 (41%), Positives = 44/87 (50%), Gaps = 1/87 (1%)

Query: 140 KKAKKAAGAKKAVKKTPKKAKKPAAAGVKKVAKSP-KKAKAAAKPKKATKSPAKPKAVKP 198
           KK +KAA  K + KK P      AAA     AK P KK  AA+K   A K PA+    + 
Sbjct: 128 KKLQKAALLKASPKKAPGTKGTAAAAAAAAAAKVPAKKITAASKKAPAQKVPAQKATGQK 187

Query: 199 KAAKPKAAKPKAAKPKAAKAKKAAAKK 225
            A  PKA K + A  + A A KA+ KK
Sbjct: 188 AAPAPKAQKGQKAPAQKAPAPKASGKK 214



 Score = 43.1 bits (100), Expect = 2e-04
 Identities = 38/101 (37%), Positives = 48/101 (47%), Gaps = 6/101 (5%)

Query: 109 KLNKKAASGEAKPKAKKAGAAKA--KKPAGA--TPKKAKKAAGAKKAVKKTPKKAKKPAA 164
           K+  +    E K K +KA   KA  KK  G   T   A  AA AK   KK    +KK  A
Sbjct: 117 KMRNRIIKNEVK-KLQKAALLKASPKKAPGTKGTAAAAAAAAAAKVPAKKITAASKKAPA 175

Query: 165 AGVKKVAKSPKKAKAAAKPKKATKSPAKPKAVKPKAAKPKA 205
             V     + +KA  A K +K  K+PA+ KA  PKA+  KA
Sbjct: 176 QKVPAQKATGQKAAPAPKAQKGQKAPAQ-KAPAPKASGKKA 215



 Score = 38.9 bits (89), Expect = 0.004
 Identities = 41/118 (34%), Positives = 48/118 (40%), Gaps = 10/118 (8%)

Query: 112 KKAASGEAKPKAK---KAGAAKAKKPAGATPKKAKKAAGAKKAVKKTPKKAKKPAAAGVK 168
           KK  + E K K     +    KAKK      K   K       +K +PKKA  P   G  
Sbjct: 93  KKIEARERKAKMTDFDRFKVMKAKKMRNRIIKNEVKKLQKAALLKASPKKA--PGTKGTA 150

Query: 169 KVAKSPKKAKAAAKPKKATKSPAKPKAVKPKAAKPKAAKPKAA-KPKAAKAKKAAAKK 225
             A     A AAAK      + A  KA   K    KA   KAA  PKA K +KA A+K
Sbjct: 151 AAAA----AAAAAKVPAKKITAASKKAPAQKVPAQKATGQKAAPAPKAQKGQKAPAQK 204



 Score = 37.4 bits (85), Expect = 0.011
 Identities = 40/115 (34%), Positives = 46/115 (40%), Gaps = 13/115 (11%)

Query: 125 KAGAAKAKKPAGATPKKAKKAAGAKKAVKKTPKKAKKPAAAGVKKVAK------SPKKAK 178
           K  A +  K   A  +KAK     +  V K  K   +     VKK+ K      SPKKA 
Sbjct: 85  KWAATRWAKKIEARERKAKMTDFDRFKVMKAKKMRNRIIKNEVKKLQKAALLKASPKKAP 144

Query: 179 ------AAAKPKKATKSPAKP-KAVKPKAAKPKAAKPKAAKPKAAKAKKAAAKKK 226
                 AAA    A K PAK   A   KA   K    KA   KAA A KA   +K
Sbjct: 145 GTKGTAAAAAAAAAAKVPAKKITAASKKAPAQKVPAQKATGQKAAPAPKAQKGQK 199


>gi|53692189 adipocyte enhancer binding protein 1 precursor [Homo
           sapiens]
          Length = 1158

 Score = 50.8 bits (120), Expect = 9e-07
 Identities = 42/115 (36%), Positives = 53/115 (46%), Gaps = 13/115 (11%)

Query: 118 EAKPKAKKA--GAAKAKKP--AGATPKKAKKAAGAKKAVKKTPKKAKKPAAAGVKKVAKS 173
           E  P+ +KA  G    K+P  A   P +  K  G K    K PK  K+     ++   + 
Sbjct: 61  EPTPRVRKAQAGGKPGKRPGTAAEVPPEKTKDKGKKGKKDKGPKVPKE----SLEGSPRP 116

Query: 174 PKKAKAAAKPKKATKSPAK--PKAVK-PKAAKPKAAKPKAAKPKAAKAKKAAAKK 225
           PKK K   KP KATK P +  PKA K PK   PKA K    KP  A  K  + K+
Sbjct: 117 PKKGKE--KPPKATKKPKEKPPKATKKPKEKPPKATKKPKEKPPKATKKPPSGKR 169



 Score = 45.1 bits (105), Expect = 5e-05
 Identities = 38/102 (37%), Positives = 44/102 (43%), Gaps = 7/102 (6%)

Query: 130 KAKKPAGATPKKAKKAAGAKKAVKKTPKKAKKPAAAGVKKVAKSPKKAKAAAKPKKATK- 188
           +A  P   TP+  K  AG K    K P  A +      K   K  KK K    PK++ + 
Sbjct: 55  EAPPPPEPTPRVRKAQAGGKPG--KRPGTAAEVPPEKTKDKGKKGKKDKGPKVPKESLEG 112

Query: 189 SPAKPKAVK---PKAAK-PKAAKPKAAKPKAAKAKKAAAKKK 226
           SP  PK  K   PKA K PK   PKA K    K  KA  K K
Sbjct: 113 SPRPPKKGKEKPPKATKKPKEKPPKATKKPKEKPPKATKKPK 154



 Score = 42.7 bits (99), Expect = 3e-04
 Identities = 38/106 (35%), Positives = 46/106 (43%), Gaps = 12/106 (11%)

Query: 112 KKAASGEAKPKAKKAGAAKAKKPAGATPKKAKKAAGAKKAVKKTPKKAK-KPAAAGVKKV 170
           +   + E  P+  K    K KK  G  PK  K++    +   + PKK K KP  A  K  
Sbjct: 78  RPGTAAEVPPEKTKDKGKKGKKDKG--PKVPKESL---EGSPRPPKKGKEKPPKATKKPK 132

Query: 171 AKSPKKA-KAAAKPKKATKSPAKPKAVKPKAAK--PKAAKPKAAKP 213
            K PK   K   KP KATK   KPK   PKA K  P   +P    P
Sbjct: 133 EKPPKATKKPKEKPPKATK---KPKEKPPKATKKPPSGKRPPILAP 175



 Score = 36.2 bits (82), Expect = 0.023
 Identities = 29/101 (28%), Positives = 37/101 (36%), Gaps = 9/101 (8%)

Query: 98  QTKGTGASGSF----KLNKKAASGEAKPKAKKAGAAKAKKPAGATPKKAKKAAGAKKAVK 153
           +TK  G  G      K+ K++  G  +P  K     K K P      K K     KK  +
Sbjct: 89  KTKDKGKKGKKDKGPKVPKESLEGSPRPPKK----GKEKPPKATKKPKEKPPKATKKPKE 144

Query: 154 KTPKKAKKPAAAGVKKVAKSPK-KAKAAAKPKKATKSPAKP 193
           K PK  KKP     K   K P  K      P +  + P  P
Sbjct: 145 KPPKATKKPKEKPPKATKKPPSGKRPPILAPSETLEWPLPP 185



 Score = 29.6 bits (65), Expect = 2.2
 Identities = 27/117 (23%), Positives = 38/117 (32%), Gaps = 3/117 (2%)

Query: 77  EKNNSRIKLGLKSLVSKGTLVQTKGTGASGSFKLNKKAASGEAKPKAKKAGAAKAKKPAG 136
           EK   + K G K    KG  V  +    S       K    +A  K K+      KKP  
Sbjct: 88  EKTKDKGKKGKKD---KGPKVPKESLEGSPRPPKKGKEKPPKATKKPKEKPPKATKKPKE 144

Query: 137 ATPKKAKKAAGAKKAVKKTPKKAKKPAAAGVKKVAKSPKKAKAAAKPKKATKSPAKP 193
             PK  KK         K P   K+P      +  + P     +  P++  +    P
Sbjct: 145 KPPKATKKPKEKPPKATKKPPSGKRPPILAPSETLEWPLPPPPSPGPEELPQEGGAP 201


>gi|153945728 microtubule-associated protein 1B [Homo sapiens]
          Length = 2468

 Score = 50.1 bits (118), Expect = 2e-06
 Identities = 39/115 (33%), Positives = 49/115 (42%), Gaps = 6/115 (5%)

Query: 118 EAKPKAKKAGAAKAKKPAGATPKKAKKAAGAKKAVKK---TP-KKAKKPAAAGVKKVAKS 173
           + KPKA K    K +       KK +K    K+  KK   TP KK +KP    VKK  K 
Sbjct: 627 DVKPKAAKEKTVKKETKVKPEDKKEEKEKPKKEVAKKEDKTPIKKEEKPKKEEVKKEVKK 686

Query: 174 PKKAKAAAKPKKATKSPAKPKAVKPKAAK--PKAAKPKAAKPKAAKAKKAAAKKK 226
             K +   +PKK  K    PK VK +  K   K  K +  +PK    K     KK
Sbjct: 687 EIKKEEKKEPKKEVKKETPPKEVKKEVKKEEKKEVKKEEKEPKKEIKKLPKDAKK 741



 Score = 50.1 bits (118), Expect = 2e-06
 Identities = 43/123 (34%), Positives = 54/123 (43%), Gaps = 9/123 (7%)

Query: 109 KLNKKAASGEAKPKAKKAGAAKAKKPAGATPKKAKKAAGAKKAVKKTPKK-AKKPAAAGV 167
           K  +K    E K + KK    + KK      KK       KK VKK  KK  KK      
Sbjct: 670 KKEEKPKKEEVKKEVKKEIKKEEKKEPKKEVKKETPPKEVKKEVKKEEKKEVKKEEKEPK 729

Query: 168 KKVAKSPKKAKAAAKPKKATKSPAKPKAVKPKAAKPKAAKPK----AAKPKAAKAKKAAA 223
           K++ K PK AK ++ P    K   KP A+KPK  K + +  K    A KPK  K K    
Sbjct: 730 KEIKKLPKDAKKSSTPLSEAK---KPAALKPKVPKKEESVKKDSVAAGKPK-EKGKIKVI 785

Query: 224 KKK 226
           KK+
Sbjct: 786 KKE 788



 Score = 49.7 bits (117), Expect = 2e-06
 Identities = 43/121 (35%), Positives = 51/121 (42%), Gaps = 11/121 (9%)

Query: 109 KLNKKAASGEAKPK---AKKAGAAKAKKPAGATPKKAKKAAGAKKAVKKTPKKAKKPAAA 165
           K +K     E KPK    KK    + KK     PKK  K     K VKK  KK +K    
Sbjct: 663 KEDKTPIKKEEKPKKEEVKKEVKKEIKKEEKKEPKKEVKKETPPKEVKKEVKKEEKKE-- 720

Query: 166 GVKKVAKSPKKAKAAAKPKKATKSPAKPKAVKPKAAKPKAAKPKAAKPKAAKAKKAAAKK 225
            VKK  K PKK     + KK  K   K      +A KP A KPK  K + +  K + A  
Sbjct: 721 -VKKEEKEPKK-----EIKKLPKDAKKSSTPLSEAKKPAALKPKVPKKEESVKKDSVAAG 774

Query: 226 K 226
           K
Sbjct: 775 K 775



 Score = 46.6 bits (109), Expect = 2e-05
 Identities = 42/119 (35%), Positives = 49/119 (41%), Gaps = 13/119 (10%)

Query: 118 EAKPKAKKAGAAKAKKPAGATPKKAKKAAGAKKAVKKTPKKAKKPAAAGVKKVAKSPKKA 177
           E K K KK  A K  K      +K KK    KK VKK  KK +K       K    PK+ 
Sbjct: 651 EEKEKPKKEVAKKEDKTPIKKEEKPKKEE-VKKEVKKEIKKEEKKEPKKEVKKETPPKEV 709

Query: 178 KAAAKP------KKATKSPAKPKAVKPKAAK------PKAAKPKAAKPKAAKAKKAAAK 224
           K   K       KK  K P K     PK AK       +A KP A KPK  K +++  K
Sbjct: 710 KKEVKKEEKKEVKKEEKEPKKEIKKLPKDAKKSSTPLSEAKKPAALKPKVPKKEESVKK 768



 Score = 42.4 bits (98), Expect = 3e-04
 Identities = 40/131 (30%), Positives = 55/131 (41%), Gaps = 13/131 (9%)

Query: 109 KLNKKAASGEA-KPKAKKAGAAKAKKPAGATPKKAKKAAGAKKAVKKTPK-----KAKKP 162
           KL ++A S E+ KP AK   +   +K +     +  K    +K  K   K     K  KP
Sbjct: 534 KLKQRADSRESLKPAAKPLPSKSVRKESKEETPEVTKVNHVEKPPKVESKEKVMVKKDKP 593

Query: 163 AAAGVK-KVAKSPKKAKAAAKPKKATKSPAKPKAVKPKAAKPKA------AKPKAAKPKA 215
                K  V +    +K    P KA  +  +   VKPKAAK K        KP+  K + 
Sbjct: 594 IKTETKPSVTEKEVPSKEEPSPVKAEVAEKQATDVKPKAAKEKTVKKETKVKPEDKKEEK 653

Query: 216 AKAKKAAAKKK 226
            K KK  AKK+
Sbjct: 654 EKPKKEVAKKE 664



 Score = 40.0 bits (92), Expect = 0.002
 Identities = 62/223 (27%), Positives = 86/223 (38%), Gaps = 30/223 (13%)

Query: 2   SETAPAETAT-------PAPVEKSPAKKKATK---KAAGAGAAKRKATGPPVSELITKAV 51
           +ET P+ T         P+PV+   A+K+AT    KAA     K++    P  +   K  
Sbjct: 596 TETKPSVTEKEVPSKEEPSPVKAEVAEKQATDVKPKAAKEKTVKKETKVKPEDKKEEKEK 655

Query: 52  AASKERNGLSLAALKKALAAGGYDVEKN-NSRIKLGLKSLVSKGTLVQTKGTGASGSFKL 110
              +         +KK       +V+K     IK   K    K    +T         K 
Sbjct: 656 PKKEVAKKEDKTPIKKEEKPKKEEVKKEVKKEIKKEEKKEPKKEVKKETPPKEVKKEVKK 715

Query: 111 NKK--AASGEAKPK---------AKKAGA--AKAKKPAGATPKKAKKAAGAKKAVKKTPK 157
            +K      E +PK         AKK+    ++AKKPA   PK  KK    +++VKK   
Sbjct: 716 EEKKEVKKEEKEPKKEIKKLPKDAKKSSTPLSEAKKPAALKPKVPKK----EESVKKDSV 771

Query: 158 KAKKPAAAGVKKVAKSPKKAKAAAKPKKATKSPAKPKAVKPKA 200
            A KP   G  KV K  K+ KAA     A  + A   AV   A
Sbjct: 772 AAGKPKEKGKIKVIK--KEGKAAEAVAAAVGTGATTAAVMAAA 812



 Score = 40.0 bits (92), Expect = 0.002
 Identities = 35/126 (27%), Positives = 50/126 (39%), Gaps = 17/126 (13%)

Query: 87   LKSLVSKGTLVQTKGTGASGSFKLNKKAASGEAKPKAKKAGAAKAKKPAGATPKKAKKAA 146
            LK  + + T  +  GT    S  + K  + G++KP       A + KPAG      K + 
Sbjct: 2235 LKKDLKEKTKTKKPGTKTKSSSPVKK--SDGKSKP------LAASPKPAGLKESSDKVSR 2286

Query: 147  GAKKAVKKTPKKAKKPAAAGVKKVAKSPKK---------AKAAAKPKKATKSPAKPKAVK 197
             A    K++ +KA KP      K A+  +K         A A+   K AT  P   K  K
Sbjct: 2287 VASPKKKESVEKAAKPTTTPEVKAARGEEKDKETKNAANASASKSAKTATAGPGTTKTTK 2346

Query: 198  PKAAKP 203
              A  P
Sbjct: 2347 SSAVPP 2352



 Score = 39.7 bits (91), Expect = 0.002
 Identities = 38/107 (35%), Positives = 52/107 (48%), Gaps = 14/107 (13%)

Query: 130  KAKKPAGATPKKA--KKAAGAKKAVKKTPKKAK-KPAAAGVKKVAKSPKKAKA---AAKP 183
            K KKP   T   +  KK+ G  K +  +PK A  K ++  V +VA SPKK ++   AAKP
Sbjct: 2244 KTKKPGTKTKSSSPVKKSDGKSKPLAASPKPAGLKESSDKVSRVA-SPKKKESVEKAAKP 2302

Query: 184  K-----KATKSPAKPKAVK--PKAAKPKAAKPKAAKPKAAKAKKAAA 223
                  KA +   K K  K    A+  K+AK   A P   K  K++A
Sbjct: 2303 TTTPEVKAARGEEKDKETKNAANASASKSAKTATAGPGTTKTTKSSA 2349



 Score = 38.5 bits (88), Expect = 0.005
 Identities = 25/69 (36%), Positives = 35/69 (50%), Gaps = 1/69 (1%)

Query: 150  KAVKKTPKKAKKPAAAGVKKVAKSP-KKAKAAAKPKKATKSPAKPKAVKPKAAKPKAAKP 208
            KA+KK  K+  K    G K  + SP KK+   +KP  A+  PA  K    K ++  + K 
Sbjct: 2233 KALKKDLKEKTKTKKPGTKTKSSSPVKKSDGKSKPLAASPKPAGLKESSDKVSRVASPKK 2292

Query: 209  KAAKPKAAK 217
            K +  KAAK
Sbjct: 2293 KESVEKAAK 2301


>gi|239758117 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 465

 Score = 49.3 bits (116), Expect = 3e-06
 Identities = 60/197 (30%), Positives = 80/197 (40%), Gaps = 18/197 (9%)

Query: 21  KKKATKKAAGAGAAKRKATGPPVSELITKAVAASKERNGLSLAAL--KKAL-----AAGG 73
           K+   +KAA AGA  R   G        KA  A  +  G  + +L  KK       AAG 
Sbjct: 150 KQPRRQKAAVAGAKSRGGEGKKPQRRGQKAATAGAKSRGGGVRSLGGKKMRRGQKGAAGA 209

Query: 74  YDVEKNNSRIKLGLKSLVSKGTLVQTKGTGASGSFKLNKKAASGEAKPKAKKAGAAKAKK 133
                     + G K+  S G   QT    A+   K  KK      K  A    AA  K 
Sbjct: 210 KRCGGGKQPRRRGQKASKSGGVRCQTPQKAAAQGVKSRKKLRQRGQKAAAAGQEAAAGKT 269

Query: 134 PAGATPKKAKKAAGAKKAVKKTPK-KAKKPAAAGVKKVAKSPKKAKAAAKPKKATKSPAK 192
             G   K   +  G KK ++K  + + +K AAAG KK    P+KA AA   ++  K   +
Sbjct: 270 CGGGGEKH--RGGGDKKPLRKNSRWRGQKAAAAGGKK----PQKAAAAGGERR--KKLRR 321

Query: 193 PKAVKPKAAKPKAAKPK 209
            KA   +A  PK  KP+
Sbjct: 322 QKAAVARAKSPK--KPR 336



 Score = 45.4 bits (106), Expect = 4e-05
 Identities = 55/233 (23%), Positives = 94/233 (40%), Gaps = 29/233 (12%)

Query: 23  KATKKAAGAGAAKRKATG-------PPVSELITKA-----VAASKERNGLSLAALKKALA 70
           +A +++  A AA+ ++TG       PP  E  T++     ++    R+G  +   +    
Sbjct: 86  RAQRRSIQAAAAQEQSTGRGCLGKEPPSQESWTRSDPRRCLSQDAVRSGSRVCRSRPQTR 145

Query: 71  AGGYDVEKNNSRIKLGLKSLVSKGTLVQTKGTGASGSFKLNKKA---ASGEAKPKAKKAG 127
            GG    +       G KS   +G   Q +G  A+ +   ++     + G  K +  + G
Sbjct: 146 GGGGKQPRRQKAAVAGAKSRGGEGKKPQRRGQKAATAGAKSRGGGVRSLGGKKMRRGQKG 205

Query: 128 AAKAKKPAGAT-PKKAKKAAGAKKAVK-KTPKKAKKPAAAGVKKVAKSPKKAKAAAKPKK 185
           AA AK+  G   P++  + A     V+ +TP+KA        KK+ +  +KA AA +   
Sbjct: 206 AAGAKRCGGGKQPRRRGQKASKSGGVRCQTPQKAAAQGVKSRKKLRQRGQKAAAAGQEAA 265

Query: 186 ATKS------------PAKPKAVKPKAAKPKAAKPKAAKPKAAKAKKAAAKKK 226
           A K+              KP     +    KAA     KP+ A A     +KK
Sbjct: 266 AGKTCGGGGEKHRGGGDKKPLRKNSRWRGQKAAAAGGKKPQKAAAAGGERRKK 318


>gi|104526627 triadin [Homo sapiens]
          Length = 729

 Score = 49.3 bits (116), Expect = 3e-06
 Identities = 38/121 (31%), Positives = 55/121 (45%), Gaps = 5/121 (4%)

Query: 109 KLNKKAASGEAKPKAKKAGAAKAKKPAGATPKKAKKAAGAKKAVKKTPKKAKKPAAAGVK 168
           +++K     + KP+ K       K+      K  +K    KKA  K  +K +K      K
Sbjct: 142 EIHKDKTEKQEKPERKIQTKVTHKEKEKGKEKVREKEKPEKKATHK--EKIEKKEKPETK 199

Query: 169 KVAKSPKKAKAAAKPKKATKSPAK---PKAVKPKAAKPKAAKPKAAKPKAAKAKKAAAKK 225
            +AK  KKAK A K ++ TK   K    + VK  AAK K  +   +KPK  + K+ AA  
Sbjct: 200 TLAKEQKKAKTAEKSEEKTKKEVKGGKQEKVKQTAAKVKEVQKTPSKPKEKEDKEKAAVS 259

Query: 226 K 226
           K
Sbjct: 260 K 260



 Score = 45.4 bits (106), Expect = 4e-05
 Identities = 62/241 (25%), Positives = 88/241 (36%), Gaps = 22/241 (9%)

Query: 2   SETAPAETATPAPVEKSPAKKKATKKAAGAGAAKRKATGPPVSELITKAVAASKERNGLS 61
           ++T   E       EKS  K K  K+  G    K K T   V E + K  +  KE+    
Sbjct: 198 TKTLAKEQKKAKTAEKSEEKTK--KEVKGGKQEKVKQTAAKVKE-VQKTPSKPKEKEDKE 254

Query: 62  LAALKKALAAGGYDVEKN------NSRIKLGLKSLVSKGTLVQTKGTGASGSFKLNKKAA 115
            AA+ K      Y   +       +  +K G    +      +        S  L +K  
Sbjct: 255 KAAVSKHEQKDQYAFCRYMIDIFVHGDLKPGQSPAIPPPLPTEQASRPTPASPALEEK-- 312

Query: 116 SGEAKPKAKKAGAAKAKKPAGATPKKAKKAAGAKKAVKKTPKKAKKPAAAGVKKVAKSPK 175
            GE K   KK  +   KK      KK++K   A    KK P KA +     VK  A++  
Sbjct: 313 EGEKKKAEKKVTSETKKKEKEDIKKKSEKET-AIDVEKKEPGKASETKQGTVKIAAQAAA 371

Query: 176 KAKAAAKPKKATKSPAKPKAVKPKAAKPKAAKPKAAK----------PKAAKAKKAAAKK 225
           K     +  K TK PA+ +  K K  + K    + AK           K  KAK   AK+
Sbjct: 372 KKDEKKEDSKKTKKPAEVEQPKGKKQEKKEKHVEPAKSPKKEHSVPSDKQVKAKTERAKE 431

Query: 226 K 226
           +
Sbjct: 432 E 432



 Score = 44.3 bits (103), Expect = 9e-05
 Identities = 63/238 (26%), Positives = 91/238 (38%), Gaps = 24/238 (10%)

Query: 8   ETATPAPVEKSPAKK--KATKKAAGAGAAKRKATGPPVSELITKAVAASKERNGLSLAAL 65
           +T  PA VE+   KK  K  K    A + K++ + P   ++  K   A +E   +S+   
Sbjct: 382 KTKKPAEVEQPKGKKQEKKEKHVEPAKSPKKEHSVPSDKQVKAKTERAKEEIGAVSI--- 438

Query: 66  KKALAAGGYD-----VEKNNSRIKLGLKSLVSKGTL-VQTKGTGASGSFKLNK------- 112
           KKA+     +     VE+   + K G  S + K    ++ K      S K  +       
Sbjct: 439 KKAVPGKKEEKTTKTVEQEIRKEKSGKTSSILKDKEPIKGKEEKVPASLKEKEPETKKDE 498

Query: 113 --KAASGEAKPKAKKAGAAKAKKPAGATPKKAKKAAGAKKAVKKTPKKAKKPAAAGVKKV 170
               A  E KPK  +    K +KP     K+AK A   K  + K      +   +  K  
Sbjct: 499 KMSKAGKEVKPKPPQLQGKKEEKPEPQIKKEAKPAISEKVQIHKQDIVKPEKTVSHGKPE 558

Query: 171 AKSPKKAKAAAKPKKATKSPAKPKAVKPKAAKP--KAAKPKAAKPKAAKAKKAAAKKK 226
            K  K+ KA    K A   P K KA   +   P  K  KPK   PK       + KKK
Sbjct: 559 EKVLKQVKAVTIEKTAKPKPTK-KAEHREREPPSIKTDKPKPT-PKGTSEVTESGKKK 614



 Score = 41.2 bits (95), Expect = 7e-04
 Identities = 41/113 (36%), Positives = 48/113 (42%), Gaps = 6/113 (5%)

Query: 112 KKAASGEAKPKAKKAGAAKAKKPAGATPKKAKKAAGAKKAVKK-TPKKAKKPAAAGVKKV 170
           KK +  E     +K    KA +    T K A +AA AKK  KK   KK KKPA     K 
Sbjct: 336 KKKSEKETAIDVEKKEPGKASETKQGTVKIAAQAA-AKKDEKKEDSKKTKKPAEVEQPKG 394

Query: 171 AKSPKKAK---AAAKPKKATKSPAKPKAVKPKAAKPKAAKPKAAKPKAAKAKK 220
            K  KK K    A  PKK    P+  K VK K  + K      +  KA   KK
Sbjct: 395 KKQEKKEKHVEPAKSPKKEHSVPS-DKQVKAKTERAKEEIGAVSIKKAVPGKK 446



 Score = 30.4 bits (67), Expect = 1.3
 Identities = 42/164 (25%), Positives = 66/164 (40%), Gaps = 23/164 (14%)

Query: 73  GYDVEKNNSRIKLGLKSLVSKGTLVQTKGTGASGSFKLNKKAASGEAKPKA-KKAGAAKA 131
           G   EK   +IK   K  +S+   +  +        K  K  + G+ + K  K+  A   
Sbjct: 516 GKKEEKPEPQIKKEAKPAISEKVQIHKQDI-----VKPEKTVSHGKPEEKVLKQVKAVTI 570

Query: 132 KKPAGATPKKAKKAAGAKK--------AVKKTPKKAKKPAAAGVKKVAKSPKKAKAAA-- 181
           +K A   PK  KKA   ++          K TPK   +   +G KK   S K++K  A  
Sbjct: 571 EKTA--KPKPTKKAEHREREPPSIKTDKPKPTPKGTSEVTESGKKKTEISEKESKEKADM 628

Query: 182 ----KPKKATKSPAKPKAVKPKAAKP-KAAKPKAAKPKAAKAKK 220
               + K +T+  +       KA KP + +K     P + KAK+
Sbjct: 629 KHLREEKVSTRKESLQLHNVTKAEKPARVSKDVEDVPASKKAKE 672


>gi|56676330 HP1-BP74 [Homo sapiens]
          Length = 553

 Score = 48.9 bits (115), Expect = 3e-06
 Identities = 59/233 (25%), Positives = 91/233 (39%), Gaps = 16/233 (6%)

Query: 8   ETATPAPVEKSPAKKKATKKAAGAGAAKRKATGPPVSE-----LITKAVAASKERNGLSL 62
           + A    VE+   ++   K A+G    K+    P +        I  A+AA  E    S 
Sbjct: 302 KNALQRAVERGQLEQITGKGASGTFQLKKSGEKPLLGGSLMEYAILSAIAAMNEPKTCST 361

Query: 63  AALKKALAAGGYDVEKNNSR--IKLGLKSLVSKGTLVQTKGTGASGSFKL--NKKAASGE 118
            ALKK +         N     +K  L+     G + Q  G G SG+F+L      + G 
Sbjct: 362 TALKKYVLENHPGTNSNYQMHLLKKTLQKCEKNGWMEQISGKGFSGTFQLCFPYYPSPGV 421

Query: 119 AKPKAKKAGAA---KAKKPAGATPKKAKKAAGAKKAVKKTPKKAKKPA-AAGVKKVAKSP 174
             PK +   +    + +  +     + ++    ++  KKTP  AK P  AA VK+    P
Sbjct: 422 LFPKKEPDDSRDEDEDEDESSEEDSEDEEPPPKRRLQKKTP--AKSPGKAASVKQRGSKP 479

Query: 175 KKAKAAAKPKKATKSPAK-PKAVKPKAAKPKAAKPKAAKPKAAKAKKAAAKKK 226
               +AA+  KA   P K P   K  A K + +     KP    +KK A   +
Sbjct: 480 APKVSAAQRGKARPLPKKAPPKAKTPAKKTRPSSTVIKKPSGGSSKKPATSAR 532



 Score = 47.4 bits (111), Expect = 1e-05
 Identities = 25/87 (28%), Positives = 50/87 (57%), Gaps = 2/87 (2%)

Query: 41  PPVSELITKAVAASKERNGLSLAALKKALAAG--GYDVEKNNSRIKLGLKSLVSKGTLVQ 98
           P +  ++T+A+ A  +++G S+ A++K +       ++E+    +K  LK  +++G + Q
Sbjct: 159 PKMDAILTEAIKACFQKSGASVVAIRKYIIHKYPSLELERRGYLLKQALKRELNRGVIKQ 218

Query: 99  TKGTGASGSFKLNKKAASGEAKPKAKK 125
            KG GASGSF + +K+     K + +K
Sbjct: 219 VKGKGASGSFVVVQKSRKTPQKSRNRK 245



 Score = 37.4 bits (85), Expect = 0.011
 Identities = 32/95 (33%), Positives = 45/95 (47%), Gaps = 13/95 (13%)

Query: 113 KAASGE---AKPKAKKAGAAKAKKPAGATPKKAKKAAGAKKAVKKTPKKAKKPAAAGVKK 169
           KAAS +   +KP  K + A + K  A   PKKA   A       KTP K  +P++  +KK
Sbjct: 468 KAASVKQRGSKPAPKVSAAQRGK--ARPLPKKAPPKA-------KTPAKKTRPSSTVIKK 518

Query: 170 VAKSPKKAKAAAKPKKATKSPAKPKAVKPKAAKPK 204
            +    K K A   +K  K P K K+   K+ + K
Sbjct: 519 PSGGSSK-KPATSARKEVKLPGKGKSTMKKSFRVK 552



 Score = 30.0 bits (66), Expect = 1.7
 Identities = 17/36 (47%), Positives = 22/36 (61%), Gaps = 3/36 (8%)

Query: 83  IKLGLKSLVSKGTLVQTKGTGASGSFKLNKKAASGE 118
           +K  L+  V +G L Q  G GASG+F+L K   SGE
Sbjct: 301 LKNALQRAVERGQLEQITGKGASGTFQLKK---SGE 333


>gi|239753329 PREDICTED: hypothetical protein XP_002345623 [Homo
           sapiens]
          Length = 351

 Score = 48.5 bits (114), Expect = 5e-06
 Identities = 47/200 (23%), Positives = 83/200 (41%), Gaps = 8/200 (4%)

Query: 26  KKAAGAGAAKRKATGP--PVSELITKAVAASKERNGLSLAALKKALAAGGYDVEKNNSRI 83
           ++ AG G      + P  P   L+  + +   +R  +  A + KA + G   + K   R 
Sbjct: 49  QRPAGRGPCATLRSHPITPAPALLLLSHSLPAQRRSMQ-ATVAKAGSPGRGRLGKEPRRR 107

Query: 84  KLGLKSLVSKGTLVQTKGTGASGSFKLNKKAASGEAKPKAKKAGAAKAKKPAGATPKKAK 143
           +   +S   +         G+       +    G+ KP+ +   AAK++   G  P+  K
Sbjct: 108 ESWTRSAPRRCPYQDASRAGSRVCRSRPQNRGGGDKKPRRRGQKAAKSRGGGGKKPRGQK 167

Query: 144 KAAGAKKAVKKTPKKAKKPAAAGVKKVAK-SPKKAKAAAKPKKATKSPAKPKAVKPKAAK 202
            A    K  +K  ++ ++ AAAG KK+ K +  K++     K A     KP+    +   
Sbjct: 168 AAGAGAKKHRKPRRRGERAAAAGGKKLQKAAAAKSRGGGGKKTAAAGGKKPR----RRRG 223

Query: 203 PKAAKPKAAKPKAAKAKKAA 222
            KAAK +    K  + +KAA
Sbjct: 224 QKAAKSRGGGDKKLERQKAA 243



 Score = 38.9 bits (89), Expect = 0.004
 Identities = 43/150 (28%), Positives = 58/150 (38%), Gaps = 22/150 (14%)

Query: 21  KKKATKKAAGAGAAKRK--------ATGPPVSELITKAVAASKERNGLSLAAL------- 65
           KK   +KAAGAGA K +        A      +L   A A S+   G   AA        
Sbjct: 161 KKPRGQKAAGAGAKKHRKPRRRGERAAAAGGKKLQKAAAAKSRGGGGKKTAAAGGKKPRR 220

Query: 66  ----KKALAAGGYDVEKNNSRIKLGLKSLVSKGTLVQTKGTGASGSFKLNKKAASGEA-K 120
               K A + GG D  K   R K  L  + S+G     +G         N K+  G   K
Sbjct: 221 RRGQKAAKSRGGGD--KKLERQKAALTGVKSRGDKKPLRGGKKQRERGQNTKSRGGGGEK 278

Query: 121 PKAKKAGAAKAKKPAGATPKKAKKAAGAKK 150
           P+   A  AK++   G  P+KA+   G  +
Sbjct: 279 PQKAAAAGAKSRGGRGEKPQKAEAGQGQNR 308



 Score = 32.3 bits (72), Expect = 0.34
 Identities = 24/80 (30%), Positives = 31/80 (38%), Gaps = 5/80 (6%)

Query: 144 KAAGAKKAVKKTPKKAKKPAAAGVKKVAKSPKKAKAAAKPKKATKSPAKPKAVKPKAAKP 203
           +  G KK  ++  K AK     G     K P+  KAA    K  + P +       A   
Sbjct: 138 RGGGDKKPRRRGQKAAKSRGGGG-----KKPRGQKAAGAGAKKHRKPRRRGERAAAAGGK 192

Query: 204 KAAKPKAAKPKAAKAKKAAA 223
           K  K  AAK +    KK AA
Sbjct: 193 KLQKAAAAKSRGGGGKKTAA 212


>gi|150170670 piccolo isoform 2 [Homo sapiens]
          Length = 4935

 Score = 48.1 bits (113), Expect = 6e-06
 Identities = 31/105 (29%), Positives = 43/105 (40%), Gaps = 2/105 (1%)

Query: 117 GEAKPKAKKAGAAKAKKPAGATPKKAKKAAGAKKAVKKTPKKAKKPAAAGVKKVAKSPKK 176
           G  K  A++AG  K         K   +  G  K   + P  AK P        AK P +
Sbjct: 445 GPGKIPAQQAGPGKTSAQQTGPTKPPSQLPGPAKPPPQQPGPAKPPPQQPGS--AKPPSQ 502

Query: 177 AKAAAKPKKATKSPAKPKAVKPKAAKPKAAKPKAAKPKAAKAKKA 221
              + KP      PAKP   +P + KP + +P +AKP A +   A
Sbjct: 503 QPGSTKPPPQQPGPAKPSPQQPGSTKPPSQQPGSAKPSAQQPSPA 547



 Score = 48.1 bits (113), Expect = 6e-06
 Identities = 30/109 (27%), Positives = 45/109 (41%), Gaps = 2/109 (1%)

Query: 116 SGEAKPKAKKAGAAKAKKPAGATPKKAKKAAGAKKAVKKTPKKAKKPAAAGVKKVAKSPK 175
           +G  K  A++ G  K         K   +  G  K   + P  AK P+        K P 
Sbjct: 454 AGPGKTSAQQTGPTKPPSQLPGPAKPPPQQPGPAKPPPQQPGSAKPPSQQPGS--TKPPP 511

Query: 176 KAKAAAKPKKATKSPAKPKAVKPKAAKPKAAKPKAAKPKAAKAKKAAAK 224
           +    AKP        KP + +P +AKP A +P  AKP A ++ K  ++
Sbjct: 512 QQPGPAKPSPQQPGSTKPPSQQPGSAKPSAQQPSPAKPSAQQSTKPVSQ 560



 Score = 44.3 bits (103), Expect = 9e-05
 Identities = 35/118 (29%), Positives = 49/118 (41%), Gaps = 2/118 (1%)

Query: 111 NKKAASGEAKPKAKKAGAAKAKKPAGATPKKAKKAAGAKKAVKKTPKKAKKPAA-AGVKK 169
           ++K+  G AKP A+ +G  K       T K   +  G  K   +    AK PA   G +K
Sbjct: 321 HEKSQPGPAKPPAQPSGLTKPLAQQPGTVKPPVQPPGTTKPPAQPLGPAKPPAQQTGSEK 380

Query: 170 VAKSPKKAKAAAKPKKATKSPAK-PKAVKPKAAKPKAAKPKAAKPKAAKAKKAAAKKK 226
            +      KA A+P    K+PA+ P   KP   +    KP A +P      KA    K
Sbjct: 381 PSSEQPGPKALAQPPGVGKTPAQQPGPAKPPTQQVGTPKPLAQQPGLQSPAKAPGPTK 438



 Score = 39.3 bits (90), Expect = 0.003
 Identities = 36/134 (26%), Positives = 49/134 (36%), Gaps = 36/134 (26%)

Query: 116 SGEAKPKAKKAGAAKAKKPAG-------------------ATPK---------KAKKAAG 147
           +G  KP +++ G     +P G                    TPK            KA G
Sbjct: 376 TGSEKPSSEQPGPKALAQPPGVGKTPAQQPGPAKPPTQQVGTPKPLAQQPGLQSPAKAPG 435

Query: 148 AKKAVKKTPKKAKKPA-AAGVKKVA-------KSPKKAKAAAKPKKATKSPAKPKAVKPK 199
             K   + P   K PA  AG  K +       K P +    AKP      PAKP   +P 
Sbjct: 436 PTKTPVQQPGPGKIPAQQAGPGKTSAQQTGPTKPPSQLPGPAKPPPQQPGPAKPPPQQPG 495

Query: 200 AAKPKAAKPKAAKP 213
           +AKP + +P + KP
Sbjct: 496 SAKPPSQQPGSTKP 509



 Score = 38.9 bits (89), Expect = 0.004
 Identities = 32/106 (30%), Positives = 44/106 (41%), Gaps = 9/106 (8%)

Query: 117 GEAKPKAKKAGAAKAKKPAGATPKKAKKAAGAKKAVKKTPKKAKKPA--AAGVKKVAKSP 174
           G AKP  ++ G+AK       + K   +  G  K   + P   K P+      K  A+ P
Sbjct: 485 GPAKPPPQQPGSAKPPSQQPGSTKPPPQQPGPAKPSPQQPGSTKPPSQQPGSAKPSAQQP 544

Query: 175 KKAKAAA----KPKKATKS--PAKPKAVKPKAAKPKA-AKPKAAKP 213
             AK +A    KP   T S  P +P  V P A +P +   PK   P
Sbjct: 545 SPAKPSAQQSTKPVSQTGSGKPLQPPTVSPSAKQPPSQGLPKTICP 590



 Score = 38.5 bits (88), Expect = 0.005
 Identities = 28/92 (30%), Positives = 36/92 (39%), Gaps = 3/92 (3%)

Query: 125 KAGAAKAKKPAGATPKKAKKAAGAKKAVKKTPKKAKKPAAAG--VKKVAKSPKKAKAAAK 182
           K       KP    P   K  A      K  P  AK PA      K +A+ P   K   +
Sbjct: 295 KPSLPSPSKPPIQQPTPGKPPAQQPGHEKSQPGPAKPPAQPSGLTKPLAQQPGTVKPPVQ 354

Query: 183 PKKATKSPAKPKA-VKPKAAKPKAAKPKAAKP 213
           P   TK PA+P    KP A +  + KP + +P
Sbjct: 355 PPGTTKPPAQPLGPAKPPAQQTGSEKPSSEQP 386



 Score = 36.2 bits (82), Expect = 0.023
 Identities = 29/105 (27%), Positives = 40/105 (38%), Gaps = 7/105 (6%)

Query: 116 SGEAKPKAKKAGAAKAK-KPAGATPKKAKKAAGAKKAVKKTPKKAKKPAAAGVKKVA--- 171
           SG  KP A++ G  K   +P G T   A+    AK   ++T  +       G K +A   
Sbjct: 336 SGLTKPLAQQPGTVKPPVQPPGTTKPPAQPLGPAKPPAQQTGSEKPSSEQPGPKALAQPP 395

Query: 172 ---KSPKKAKAAAKPKKATKSPAKPKAVKPKAAKPKAAKPKAAKP 213
              K+P +    AKP        KP A +P    P  A      P
Sbjct: 396 GVGKTPAQQPGPAKPPTQQVGTPKPLAQQPGLQSPAKAPGPTKTP 440



 Score = 35.8 bits (81), Expect = 0.031
 Identities = 38/138 (27%), Positives = 51/138 (36%), Gaps = 46/138 (33%)

Query: 117 GEAKPKAKKAGAAKAKKPAGATPKKAKKAAGAKKAVKKTPKKAKKPAAAGVKKVA----- 171
           G AKP A++ G+   +KP+   P    KA      V KTP +   PA    ++V      
Sbjct: 367 GPAKPPAQQTGS---EKPSSEQP--GPKALAQPPGVGKTPAQQPGPAKPPTQQVGTPKPL 421

Query: 172 ------KSPKKA------------------------KAAA------KPKKATKSPAKPKA 195
                 +SP KA                        K +A      KP      PAKP  
Sbjct: 422 AQQPGLQSPAKAPGPTKTPVQQPGPGKIPAQQAGPGKTSAQQTGPTKPPSQLPGPAKPPP 481

Query: 196 VKPKAAKPKAAKPKAAKP 213
            +P  AKP   +P +AKP
Sbjct: 482 QQPGPAKPPPQQPGSAKP 499



 Score = 35.4 bits (80), Expect = 0.040
 Identities = 28/84 (33%), Positives = 39/84 (46%), Gaps = 5/84 (5%)

Query: 115  ASGEAKPKAKKAGAAKAKKPAGATPKKAKKAAGAKKAVKKTPKKAKKPAAAGVKKVAKSP 174
            ++G+A P   K+   K +  A A  K   KA  A   VK+T  + K P     K +   P
Sbjct: 982  STGQAPPAPAKSIPVKKETKAPAAEKLEPKAEQAP-TVKRTETEKKPPPIKDSKSLTAEP 1040

Query: 175  KKAKAAAKPKKATKSPAKPKAVKP 198
            +K   A  P K  KSP KP++  P
Sbjct: 1041 QK---AVLPTKLEKSP-KPESTCP 1060



 Score = 34.7 bits (78), Expect = 0.068
 Identities = 27/105 (25%), Positives = 41/105 (39%), Gaps = 4/105 (3%)

Query: 126 AGAAKAKKPAGATPKK---AKKAAGAKKAVKKTPKKAKKPAAAGVKKV-AKSPKKAKAAA 181
           A +  + +P   +PKK    K+        KK P   K+P   G     AK P +A + +
Sbjct: 671 AVSKSSPQPQQTSPKKDAAPKQDLSKAPEPKKPPPLVKQPTLHGSPSAKAKQPPEADSLS 730

Query: 182 KPKKATKSPAKPKAVKPKAAKPKAAKPKAAKPKAAKAKKAAAKKK 226
           KP    +     +  K   A  K  +PK  KP       ++A  K
Sbjct: 731 KPAPPKEPSVPSEQDKAPVADDKPKQPKMVKPTTDLVSSSSATTK 775



 Score = 31.6 bits (70), Expect = 0.58
 Identities = 30/119 (25%), Positives = 43/119 (36%), Gaps = 18/119 (15%)

Query: 120 KPKAKKAGAAKAKKPAGATPKKAKKAAGAKKAVKKTPKKAKKP------------AAAGV 167
           KP  K+ G  +       TPK        K  +K  P    KP            A   +
Sbjct: 217 KPIPKQQGPGRDPLQQDGTPKSISSQQPEK--IKSQPPGTGKPIQGPTQTPQTDHAKLPL 274

Query: 168 KKVAKSPKKAKA----AAKPKKATKSPAKPKAVKPKAAKPKAAKPKAAKPKAAKAKKAA 222
           ++ A  P+  +A        K +  SP+KP   +P   KP A +P   K +   AK  A
Sbjct: 275 QRDASRPQTKQADIVRGESVKPSLPSPSKPPIQQPTPGKPPAQQPGHEKSQPGPAKPPA 333



 Score = 30.4 bits (67), Expect = 1.3
 Identities = 27/98 (27%), Positives = 39/98 (39%), Gaps = 14/98 (14%)

Query: 119 AKPKAKKAGAAKAKKPAGATPKKAKKAAGAKKAVKKTPKKAKKPAAA-GVKKVAKSPKKA 177
           ++P+ K+A   + +    + P  +K          + P   K PA   G +K    P  A
Sbjct: 279 SRPQTKQADIVRGESVKPSLPSPSKPPI-------QQPTPGKPPAQQPGHEK--SQPGPA 329

Query: 178 KAAAKPKKATKSPAKPKAVKPKAAKPKAAKPKAAKPKA 215
           K  A+P   TK    P A +P   KP    P   KP A
Sbjct: 330 KPPAQPSGLTK----PLAQQPGTVKPPVQPPGTTKPPA 363



 Score = 28.1 bits (61), Expect = 6.4
 Identities = 23/80 (28%), Positives = 34/80 (42%), Gaps = 2/80 (2%)

Query: 143 KKAAGAKKA-VKKTPK-KAKKPAAAGVKKVAKSPKKAKAAAKPKKATKSPAKPKAVKPKA 200
           K+A G   A V  +P+ K K         V+KS  + +  +  K A       KA +PK 
Sbjct: 643 KRALGGDLAPVPSSPQPKLKTAPVTTTSAVSKSSPQPQQTSPKKDAAPKQDLSKAPEPKK 702

Query: 201 AKPKAAKPKAAKPKAAKAKK 220
             P   +P      +AKAK+
Sbjct: 703 PPPLVKQPTLHGSPSAKAKQ 722



 Score = 28.1 bits (61), Expect = 6.4
 Identities = 21/81 (25%), Positives = 34/81 (41%), Gaps = 12/81 (14%)

Query: 146  AGAKKAVKKTPKKAKKPAAAGVKKVAKSPKKAKAAAKPKKATKSPAKPKAVKPKAAKPKA 205
            +G    +K+ P  ++ P + G       P K+   A P     +PAK   VK +   P A
Sbjct: 958  SGPGAPMKQAPAPSQPPTSQG-------PPKSTGQAPP-----APAKSIPVKKETKAPAA 1005

Query: 206  AKPKAAKPKAAKAKKAAAKKK 226
             K +    +A   K+   +KK
Sbjct: 1006 EKLEPKAEQAPTVKRTETEKK 1026


>gi|150378539 piccolo isoform 1 [Homo sapiens]
          Length = 5142

 Score = 48.1 bits (113), Expect = 6e-06
 Identities = 31/105 (29%), Positives = 43/105 (40%), Gaps = 2/105 (1%)

Query: 117 GEAKPKAKKAGAAKAKKPAGATPKKAKKAAGAKKAVKKTPKKAKKPAAAGVKKVAKSPKK 176
           G  K  A++AG  K         K   +  G  K   + P  AK P        AK P +
Sbjct: 445 GPGKIPAQQAGPGKTSAQQTGPTKPPSQLPGPAKPPPQQPGPAKPPPQQPGS--AKPPSQ 502

Query: 177 AKAAAKPKKATKSPAKPKAVKPKAAKPKAAKPKAAKPKAAKAKKA 221
              + KP      PAKP   +P + KP + +P +AKP A +   A
Sbjct: 503 QPGSTKPPPQQPGPAKPSPQQPGSTKPPSQQPGSAKPSAQQPSPA 547



 Score = 48.1 bits (113), Expect = 6e-06
 Identities = 30/109 (27%), Positives = 45/109 (41%), Gaps = 2/109 (1%)

Query: 116 SGEAKPKAKKAGAAKAKKPAGATPKKAKKAAGAKKAVKKTPKKAKKPAAAGVKKVAKSPK 175
           +G  K  A++ G  K         K   +  G  K   + P  AK P+        K P 
Sbjct: 454 AGPGKTSAQQTGPTKPPSQLPGPAKPPPQQPGPAKPPPQQPGSAKPPSQQPGS--TKPPP 511

Query: 176 KAKAAAKPKKATKSPAKPKAVKPKAAKPKAAKPKAAKPKAAKAKKAAAK 224
           +    AKP        KP + +P +AKP A +P  AKP A ++ K  ++
Sbjct: 512 QQPGPAKPSPQQPGSTKPPSQQPGSAKPSAQQPSPAKPSAQQSTKPVSQ 560



 Score = 44.3 bits (103), Expect = 9e-05
 Identities = 35/118 (29%), Positives = 49/118 (41%), Gaps = 2/118 (1%)

Query: 111 NKKAASGEAKPKAKKAGAAKAKKPAGATPKKAKKAAGAKKAVKKTPKKAKKPAA-AGVKK 169
           ++K+  G AKP A+ +G  K       T K   +  G  K   +    AK PA   G +K
Sbjct: 321 HEKSQPGPAKPPAQPSGLTKPLAQQPGTVKPPVQPPGTTKPPAQPLGPAKPPAQQTGSEK 380

Query: 170 VAKSPKKAKAAAKPKKATKSPAK-PKAVKPKAAKPKAAKPKAAKPKAAKAKKAAAKKK 226
            +      KA A+P    K+PA+ P   KP   +    KP A +P      KA    K
Sbjct: 381 PSSEQPGPKALAQPPGVGKTPAQQPGPAKPPTQQVGTPKPLAQQPGLQSPAKAPGPTK 438



 Score = 39.3 bits (90), Expect = 0.003
 Identities = 36/134 (26%), Positives = 49/134 (36%), Gaps = 36/134 (26%)

Query: 116 SGEAKPKAKKAGAAKAKKPAG-------------------ATPK---------KAKKAAG 147
           +G  KP +++ G     +P G                    TPK            KA G
Sbjct: 376 TGSEKPSSEQPGPKALAQPPGVGKTPAQQPGPAKPPTQQVGTPKPLAQQPGLQSPAKAPG 435

Query: 148 AKKAVKKTPKKAKKPA-AAGVKKVA-------KSPKKAKAAAKPKKATKSPAKPKAVKPK 199
             K   + P   K PA  AG  K +       K P +    AKP      PAKP   +P 
Sbjct: 436 PTKTPVQQPGPGKIPAQQAGPGKTSAQQTGPTKPPSQLPGPAKPPPQQPGPAKPPPQQPG 495

Query: 200 AAKPKAAKPKAAKP 213
           +AKP + +P + KP
Sbjct: 496 SAKPPSQQPGSTKP 509



 Score = 38.9 bits (89), Expect = 0.004
 Identities = 32/106 (30%), Positives = 44/106 (41%), Gaps = 9/106 (8%)

Query: 117 GEAKPKAKKAGAAKAKKPAGATPKKAKKAAGAKKAVKKTPKKAKKPA--AAGVKKVAKSP 174
           G AKP  ++ G+AK       + K   +  G  K   + P   K P+      K  A+ P
Sbjct: 485 GPAKPPPQQPGSAKPPSQQPGSTKPPPQQPGPAKPSPQQPGSTKPPSQQPGSAKPSAQQP 544

Query: 175 KKAKAAA----KPKKATKS--PAKPKAVKPKAAKPKA-AKPKAAKP 213
             AK +A    KP   T S  P +P  V P A +P +   PK   P
Sbjct: 545 SPAKPSAQQSTKPVSQTGSGKPLQPPTVSPSAKQPPSQGLPKTICP 590



 Score = 38.5 bits (88), Expect = 0.005
 Identities = 28/92 (30%), Positives = 36/92 (39%), Gaps = 3/92 (3%)

Query: 125 KAGAAKAKKPAGATPKKAKKAAGAKKAVKKTPKKAKKPAAAG--VKKVAKSPKKAKAAAK 182
           K       KP    P   K  A      K  P  AK PA      K +A+ P   K   +
Sbjct: 295 KPSLPSPSKPPIQQPTPGKPPAQQPGHEKSQPGPAKPPAQPSGLTKPLAQQPGTVKPPVQ 354

Query: 183 PKKATKSPAKPKA-VKPKAAKPKAAKPKAAKP 213
           P   TK PA+P    KP A +  + KP + +P
Sbjct: 355 PPGTTKPPAQPLGPAKPPAQQTGSEKPSSEQP 386



 Score = 36.2 bits (82), Expect = 0.023
 Identities = 29/105 (27%), Positives = 40/105 (38%), Gaps = 7/105 (6%)

Query: 116 SGEAKPKAKKAGAAKAK-KPAGATPKKAKKAAGAKKAVKKTPKKAKKPAAAGVKKVA--- 171
           SG  KP A++ G  K   +P G T   A+    AK   ++T  +       G K +A   
Sbjct: 336 SGLTKPLAQQPGTVKPPVQPPGTTKPPAQPLGPAKPPAQQTGSEKPSSEQPGPKALAQPP 395

Query: 172 ---KSPKKAKAAAKPKKATKSPAKPKAVKPKAAKPKAAKPKAAKP 213
              K+P +    AKP        KP A +P    P  A      P
Sbjct: 396 GVGKTPAQQPGPAKPPTQQVGTPKPLAQQPGLQSPAKAPGPTKTP 440



 Score = 35.8 bits (81), Expect = 0.031
 Identities = 38/138 (27%), Positives = 51/138 (36%), Gaps = 46/138 (33%)

Query: 117 GEAKPKAKKAGAAKAKKPAGATPKKAKKAAGAKKAVKKTPKKAKKPAAAGVKKVA----- 171
           G AKP A++ G+   +KP+   P    KA      V KTP +   PA    ++V      
Sbjct: 367 GPAKPPAQQTGS---EKPSSEQP--GPKALAQPPGVGKTPAQQPGPAKPPTQQVGTPKPL 421

Query: 172 ------KSPKKA------------------------KAAA------KPKKATKSPAKPKA 195
                 +SP KA                        K +A      KP      PAKP  
Sbjct: 422 AQQPGLQSPAKAPGPTKTPVQQPGPGKIPAQQAGPGKTSAQQTGPTKPPSQLPGPAKPPP 481

Query: 196 VKPKAAKPKAAKPKAAKP 213
            +P  AKP   +P +AKP
Sbjct: 482 QQPGPAKPPPQQPGSAKP 499



 Score = 35.4 bits (80), Expect = 0.040
 Identities = 28/84 (33%), Positives = 39/84 (46%), Gaps = 5/84 (5%)

Query: 115  ASGEAKPKAKKAGAAKAKKPAGATPKKAKKAAGAKKAVKKTPKKAKKPAAAGVKKVAKSP 174
            ++G+A P   K+   K +  A A  K   KA  A   VK+T  + K P     K +   P
Sbjct: 982  STGQAPPAPAKSIPVKKETKAPAAEKLEPKAEQAP-TVKRTETEKKPPPIKDSKSLTAEP 1040

Query: 175  KKAKAAAKPKKATKSPAKPKAVKP 198
            +K   A  P K  KSP KP++  P
Sbjct: 1041 QK---AVLPTKLEKSP-KPESTCP 1060



 Score = 34.7 bits (78), Expect = 0.068
 Identities = 27/105 (25%), Positives = 41/105 (39%), Gaps = 4/105 (3%)

Query: 126 AGAAKAKKPAGATPKK---AKKAAGAKKAVKKTPKKAKKPAAAGVKKV-AKSPKKAKAAA 181
           A +  + +P   +PKK    K+        KK P   K+P   G     AK P +A + +
Sbjct: 671 AVSKSSPQPQQTSPKKDAAPKQDLSKAPEPKKPPPLVKQPTLHGSPSAKAKQPPEADSLS 730

Query: 182 KPKKATKSPAKPKAVKPKAAKPKAAKPKAAKPKAAKAKKAAAKKK 226
           KP    +     +  K   A  K  +PK  KP       ++A  K
Sbjct: 731 KPAPPKEPSVPSEQDKAPVADDKPKQPKMVKPTTDLVSSSSATTK 775



 Score = 31.6 bits (70), Expect = 0.58
 Identities = 30/119 (25%), Positives = 43/119 (36%), Gaps = 18/119 (15%)

Query: 120 KPKAKKAGAAKAKKPAGATPKKAKKAAGAKKAVKKTPKKAKKP------------AAAGV 167
           KP  K+ G  +       TPK        K  +K  P    KP            A   +
Sbjct: 217 KPIPKQQGPGRDPLQQDGTPKSISSQQPEK--IKSQPPGTGKPIQGPTQTPQTDHAKLPL 274

Query: 168 KKVAKSPKKAKA----AAKPKKATKSPAKPKAVKPKAAKPKAAKPKAAKPKAAKAKKAA 222
           ++ A  P+  +A        K +  SP+KP   +P   KP A +P   K +   AK  A
Sbjct: 275 QRDASRPQTKQADIVRGESVKPSLPSPSKPPIQQPTPGKPPAQQPGHEKSQPGPAKPPA 333



 Score = 30.4 bits (67), Expect = 1.3
 Identities = 27/98 (27%), Positives = 39/98 (39%), Gaps = 14/98 (14%)

Query: 119 AKPKAKKAGAAKAKKPAGATPKKAKKAAGAKKAVKKTPKKAKKPAAA-GVKKVAKSPKKA 177
           ++P+ K+A   + +    + P  +K          + P   K PA   G +K    P  A
Sbjct: 279 SRPQTKQADIVRGESVKPSLPSPSKPPI-------QQPTPGKPPAQQPGHEK--SQPGPA 329

Query: 178 KAAAKPKKATKSPAKPKAVKPKAAKPKAAKPKAAKPKA 215
           K  A+P   TK    P A +P   KP    P   KP A
Sbjct: 330 KPPAQPSGLTK----PLAQQPGTVKPPVQPPGTTKPPA 363



 Score = 28.1 bits (61), Expect = 6.4
 Identities = 23/80 (28%), Positives = 34/80 (42%), Gaps = 2/80 (2%)

Query: 143 KKAAGAKKA-VKKTPK-KAKKPAAAGVKKVAKSPKKAKAAAKPKKATKSPAKPKAVKPKA 200
           K+A G   A V  +P+ K K         V+KS  + +  +  K A       KA +PK 
Sbjct: 643 KRALGGDLAPVPSSPQPKLKTAPVTTTSAVSKSSPQPQQTSPKKDAAPKQDLSKAPEPKK 702

Query: 201 AKPKAAKPKAAKPKAAKAKK 220
             P   +P      +AKAK+
Sbjct: 703 PPPLVKQPTLHGSPSAKAKQ 722



 Score = 28.1 bits (61), Expect = 6.4
 Identities = 21/81 (25%), Positives = 34/81 (41%), Gaps = 12/81 (14%)

Query: 146  AGAKKAVKKTPKKAKKPAAAGVKKVAKSPKKAKAAAKPKKATKSPAKPKAVKPKAAKPKA 205
            +G    +K+ P  ++ P + G       P K+   A P     +PAK   VK +   P A
Sbjct: 958  SGPGAPMKQAPAPSQPPTSQG-------PPKSTGQAPP-----APAKSIPVKKETKAPAA 1005

Query: 206  AKPKAAKPKAAKAKKAAAKKK 226
             K +    +A   K+   +KK
Sbjct: 1006 EKLEPKAEQAPTVKRTETEKK 1026


>gi|29244924 chromodomain helicase DNA binding protein 6 [Homo
           sapiens]
          Length = 2715

 Score = 48.1 bits (113), Expect = 6e-06
 Identities = 36/130 (27%), Positives = 58/130 (44%), Gaps = 14/130 (10%)

Query: 97  VQTKGTGASGSFKLNKKAASGEAKPKAKKAGAAKAKKPAGATPKKAKKAAGAKKAVKKTP 156
           ++  G G +G  K  KK   G+ +      GAAK  K     PK+ ++    K+     P
Sbjct: 82  MEDSGGGGTGVKKKRKKKEPGDQE------GAAKGSKDREPKPKRKREPKEPKE-----P 130

Query: 157 KKAKKPAAAGVKKVAKSPKKAKAAAKPKKATKSPAKPKAVKPKAAKPKAAKPKAAKPKAA 216
           +KAK+P  A   K  K PK+   A K +K  ++    +A + ++    AA+ K+ K    
Sbjct: 131 RKAKEPKKA---KEHKEPKQKDGAKKARKPREASGTKEAKEKRSCTDSAARTKSRKASKE 187

Query: 217 KAKKAAAKKK 226
           +      KKK
Sbjct: 188 QGPTPVEKKK 197


>gi|153791662 coiled-coil domain containing 71 [Homo sapiens]
          Length = 467

 Score = 47.8 bits (112), Expect = 8e-06
 Identities = 51/152 (33%), Positives = 67/152 (44%), Gaps = 13/152 (8%)

Query: 88  KSLVSKGTLVQT-KGTGAS---GSFKLNK-KAASGEAKPKAKKAGAAKAKKPAGA-TPKK 141
           +   SKG    T KG GA    GS   +K   A+G    +  K G+A   K A A   + 
Sbjct: 229 RKTTSKGPKCLTRKGPGAGPRRGSGHQSKTNRATGSPSVRRMKGGSALGTKTAQAKVART 288

Query: 142 AKKAAGAKKAVKKTPKKAKKPAAAGVKKVAKSPKKAKAAAKPKKA------TKSPAKPKA 195
             KAA A+  V +T  KA K  A       K+  KAKAA    KA       K+ AK KA
Sbjct: 289 LAKAARAQAKVARTQAKAAKARAKAKAAQVKAKAKAKAAQVKAKAKVMAAWAKAKAKAKA 348

Query: 196 VKPKAAKPKAAKPKAAKPK-AAKAKKAAAKKK 226
           V+ KA   +       +PK +AKA+     +K
Sbjct: 349 VRAKAKVARTQPRGRGRPKGSAKARTTRKGQK 380



 Score = 45.4 bits (106), Expect = 4e-05
 Identities = 57/206 (27%), Positives = 77/206 (37%), Gaps = 13/206 (6%)

Query: 18  SPAK-KKATKKAAGAGAAK--RKATGPPVSELITKAVAASKERNGLSLAALKKALAAGGY 74
           SP K +K++ K  G    K  RK T      L  K   A   R   S    K   A G  
Sbjct: 208 SPLKLRKSSGKGPGNPRPKAPRKTTSKGPKCLTRKGPGAGPRRG--SGHQSKTNRATGSP 265

Query: 75  DVEKNNSRIKLGLKSLVSKGTLVQTKGTGASGSF-KLNKKAASGEAKPKAKKAGAAKAKK 133
            V +      LG K+  +K      K   A     +   KAA   AK KA +   AKAK 
Sbjct: 266 SVRRMKGGSALGTKTAQAKVARTLAKAARAQAKVARTQAKAAKARAKAKAAQV-KAKAKA 324

Query: 134 PAGATPKKAKKAAGAKKAVKKTPKKAKKPAAAGVKKVAKSPKKAKAAAKPKKATKSPAKP 193
            A     KAK  A   KA      KAK  A     KVA++  + +   K     ++  K 
Sbjct: 325 KAAQVKAKAKVMAAWAKA------KAKAKAVRAKAKVARTQPRGRGRPKGSAKARTTRKG 378

Query: 194 KAVKPKAAKPKAAKPKAAKPKAAKAK 219
           +  +P+    K  + + AK    K +
Sbjct: 379 QKNRPETVGQKRKRAEEAKDLPPKKR 404


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.298    0.113    0.291 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 8,112,175
Number of Sequences: 37866
Number of extensions: 373058
Number of successful extensions: 7504
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 323
Number of HSP's successfully gapped in prelim test: 488
Number of HSP's that attempted gapping in prelim test: 3278
Number of HSP's gapped (non-prelim): 2745
length of query: 226
length of database: 18,247,518
effective HSP length: 99
effective length of query: 127
effective length of database: 14,498,784
effective search space: 1841345568
effective search space used: 1841345568
T: 11
A: 40
X1: 17 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 43 (21.7 bits)
S2: 60 (27.7 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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