Home |
Table of Contents |
Search text |
Search genes |
Search sequences |
Purchase |
FAQ |
Blog |
Help
Search of human proteins with 4885325
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|4885325 G protein-coupled receptor 3 [Homo sapiens]
(330 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|4885325 G protein-coupled receptor 3 [Homo sapiens] 664 0.0
gi|4885341 G protein-coupled receptor 6 [Homo sapiens] 390 e-108
gi|4885295 G protein-coupled receptor 12 [Homo sapiens] 385 e-107
gi|7305013 lysophosphatidic acid receptor 2 [Homo sapiens] 134 1e-31
gi|13540517 endothelial differentiation, sphingolipid G-protein-... 132 4e-31
gi|6912348 lysophosphatidic acid receptor 3 [Homo sapiens] 131 9e-31
gi|134244587 endothelial differentiation, sphingolipid G-protein... 127 2e-29
gi|13027636 sphingosine-1-phosphate receptor 1 [Homo sapiens] 126 2e-29
gi|16950638 lysophosphatidic acid receptor 1 [Homo sapiens] 122 3e-28
gi|16950636 lysophosphatidic acid receptor 1 [Homo sapiens] 122 3e-28
gi|119508433 melanocortin 4 receptor [Homo sapiens] 115 7e-26
gi|5174535 melanocortin 5 receptor [Homo sapiens] 113 2e-25
gi|170671732 melanocortin 3 receptor [Homo sapiens] 112 5e-25
gi|4501951 adenosine A2b receptor [Homo sapiens] 112 6e-25
gi|4503459 sphingosine-1-phosphate receptor 4 precursor [Homo sa... 108 5e-24
gi|237681179 cannabinoid receptor 1 isoform a [Homo sapiens] 108 7e-24
gi|237681175 cannabinoid receptor 1 isoform a [Homo sapiens] 108 7e-24
gi|237681173 cannabinoid receptor 1 isoform a [Homo sapiens] 108 7e-24
gi|237681067 cannabinoid receptor 1 isoform a [Homo sapiens] 108 7e-24
gi|38683844 cannabinoid receptor 1 isoform a [Homo sapiens] 108 7e-24
gi|237681065 cannabinoid receptor 1 isoform b [Homo sapiens] 108 7e-24
gi|38788193 sphingosine-1-phosphate receptor 3 [Homo sapiens] 107 1e-23
gi|4502929 cannabinoid receptor 2 (macrophage) [Homo sapiens] 102 6e-22
gi|4505127 melanocortin 2 receptor [Homo sapiens] 99 7e-21
gi|4501953 adenosine A3 receptor isoform 2 [Homo sapiens] 98 1e-20
gi|193083134 melanocortin 1 receptor [Homo sapiens] 97 2e-20
gi|5921992 adenosine A2a receptor [Homo sapiens] 93 4e-19
gi|115305569 adenosine A1 receptor [Homo sapiens] 88 1e-17
gi|4501947 adenosine A1 receptor [Homo sapiens] 88 1e-17
gi|197085610 histamine receptor H2 isoform 1 [Homo sapiens] 86 5e-17
>gi|4885325 G protein-coupled receptor 3 [Homo sapiens]
Length = 330
Score = 664 bits (1713), Expect = 0.0
Identities = 330/330 (100%), Positives = 330/330 (100%)
Query: 1 MMWGAGSPLAWLSAGSGNVNVSSVGPAEGPTGPAAPLPSPKAWDVVLCISGTLVSCENAL 60
MMWGAGSPLAWLSAGSGNVNVSSVGPAEGPTGPAAPLPSPKAWDVVLCISGTLVSCENAL
Sbjct: 1 MMWGAGSPLAWLSAGSGNVNVSSVGPAEGPTGPAAPLPSPKAWDVVLCISGTLVSCENAL 60
Query: 61 VVAIIVGTPAFRAPMFLLVGSLAVADLLAGLGLVLHFAAVFCIGSAEMSLVLVGVLAMAF 120
VVAIIVGTPAFRAPMFLLVGSLAVADLLAGLGLVLHFAAVFCIGSAEMSLVLVGVLAMAF
Sbjct: 61 VVAIIVGTPAFRAPMFLLVGSLAVADLLAGLGLVLHFAAVFCIGSAEMSLVLVGVLAMAF 120
Query: 121 TASIGSLLAITVDRYLSLYNALTYYSETTVTRTYVMLALVWGGALGLGLLPVLAWNCLDG 180
TASIGSLLAITVDRYLSLYNALTYYSETTVTRTYVMLALVWGGALGLGLLPVLAWNCLDG
Sbjct: 121 TASIGSLLAITVDRYLSLYNALTYYSETTVTRTYVMLALVWGGALGLGLLPVLAWNCLDG 180
Query: 181 LTTCGVVYPLSKNHLVVLAIAFFMVFGIMLQLYAQICRIVCRHAQQIALQRHLLPASHYV 240
LTTCGVVYPLSKNHLVVLAIAFFMVFGIMLQLYAQICRIVCRHAQQIALQRHLLPASHYV
Sbjct: 181 LTTCGVVYPLSKNHLVVLAIAFFMVFGIMLQLYAQICRIVCRHAQQIALQRHLLPASHYV 240
Query: 241 ATRKGIATLAVVLGAFAACWLPFTVYCLLGDAHSPPLYTYLTLLPATYNSMINPIIYAFR 300
ATRKGIATLAVVLGAFAACWLPFTVYCLLGDAHSPPLYTYLTLLPATYNSMINPIIYAFR
Sbjct: 241 ATRKGIATLAVVLGAFAACWLPFTVYCLLGDAHSPPLYTYLTLLPATYNSMINPIIYAFR 300
Query: 301 NQDVQKVLWAVCCCCSSSKIPFRSRSPSDV 330
NQDVQKVLWAVCCCCSSSKIPFRSRSPSDV
Sbjct: 301 NQDVQKVLWAVCCCCSSSKIPFRSRSPSDV 330
>gi|4885341 G protein-coupled receptor 6 [Homo sapiens]
Length = 362
Score = 390 bits (1001), Expect = e-108
Identities = 193/329 (58%), Positives = 239/329 (72%), Gaps = 3/329 (0%)
Query: 3 WGAGSPLAWLSAGSGNVNVS-SVGPAEGPTGPAAPLPSPKAWDVVLCISGTLVSCENALV 61
WG + A + G N ++ S + GP G P +P WDV+LC+SGT+++ ENALV
Sbjct: 36 WGPPAAAALGAGGGANGSLELSSQLSAGPPGLLLPAVNP--WDVLLCVSGTVIAGENALV 93
Query: 62 VAIIVGTPAFRAPMFLLVGSLAVADLLAGLGLVLHFAAVFCIGSAEMSLVLVGVLAMAFT 121
VA+I TPA R PMF+LVGSLA ADLLAG GL+LHF + + S +SL+ VG L +F
Sbjct: 94 VALIASTPALRTPMFVLVGSLATADLLAGCGLILHFVFQYLVPSETVSLLTVGFLVASFA 153
Query: 122 ASIGSLLAITVDRYLSLYNALTYYSETTVTRTYVMLALVWGGALGLGLLPVLAWNCLDGL 181
AS+ SLLAITVDRYLSLYNALTYYS T+ +++LA W +LGLGLLPVL WNCL
Sbjct: 154 ASVSSLLAITVDRYLSLYNALTYYSRRTLLGVHLLLAATWTVSLGLGLLPVLGWNCLAER 213
Query: 182 TTCGVVYPLSKNHLVVLAIAFFMVFGIMLQLYAQICRIVCRHAQQIALQRHLLPASHYVA 241
C VV PL+++H+ +L+ AFFMVFGIML LY +IC++V RHA QIALQ+H L H A
Sbjct: 214 AACSVVRPLARSHVALLSAAFFMVFGIMLHLYVRICQVVWRHAHQIALQQHCLAPPHLAA 273
Query: 242 TRKGIATLAVVLGAFAACWLPFTVYCLLGDAHSPPLYTYLTLLPATYNSMINPIIYAFRN 301
TRKG+ TLAVVLG F A WLPF +YC++G P +YTY TLLPATYNSMINPIIYAFRN
Sbjct: 274 TRKGVGTLAVVLGTFGASWLPFAIYCVVGSHEDPAVYTYATLLPATYNSMINPIIYAFRN 333
Query: 302 QDVQKVLWAVCCCCSSSKIPFRSRSPSDV 330
Q++Q+ LW + C C SK+PFRSRSPS+V
Sbjct: 334 QEIQRALWLLLCGCFQSKVPFRSRSPSEV 362
>gi|4885295 G protein-coupled receptor 12 [Homo sapiens]
Length = 334
Score = 385 bits (988), Expect = e-107
Identities = 186/326 (57%), Positives = 240/326 (73%), Gaps = 1/326 (0%)
Query: 5 AGSPLAWLSAGSGNVNVSSVGPAEGPTGPAAPLPSPKAWDVVLCISGTLVSCENALVVAI 64
+G P +L A + N+S+ + P P WD+VLC SGTL+SCENA+VV I
Sbjct: 10 SGLPRDYLDAAAAE-NISAAVSSRVPAVEPEPELVVNPWDIVLCTSGTLISCENAIVVLI 68
Query: 65 IVGTPAFRAPMFLLVGSLAVADLLAGLGLVLHFAAVFCIGSAEMSLVLVGVLAMAFTASI 124
I P+ RAPMFLL+GSLA+ADLLAG+GL+ +F + + S LV +G++ +F+AS+
Sbjct: 69 IFHNPSLRAPMFLLIGSLALADLLAGIGLITNFVFAYLLQSEATKLVTIGLIVASFSASV 128
Query: 125 GSLLAITVDRYLSLYNALTYYSETTVTRTYVMLALVWGGALGLGLLPVLAWNCLDGLTTC 184
SLLAITVDRYLSLY ALTY+SE TVT TYVML ++WG ++ LGLLPV+ WNCL +TC
Sbjct: 129 CSLLAITVDRYLSLYYALTYHSERTVTFTYVMLVMLWGTSICLGLLPVMGWNCLRDESTC 188
Query: 185 GVVYPLSKNHLVVLAIAFFMVFGIMLQLYAQICRIVCRHAQQIALQRHLLPASHYVATRK 244
VV PL+KN+ +L+++F +F +MLQLY QIC+IV RHA QIALQ H L SHYV TRK
Sbjct: 189 SVVRPLTKNNAAILSVSFLFMFALMLQLYIQICKIVMRHAHQIALQHHFLATSHYVTTRK 248
Query: 245 GIATLAVVLGAFAACWLPFTVYCLLGDAHSPPLYTYLTLLPATYNSMINPIIYAFRNQDV 304
G++TLA++LG FAACW+PFT+Y L+ D P +YTY TLLPATYNS+INP+IYAFRNQ++
Sbjct: 249 GVSTLAIILGTFAACWMPFTLYSLIADYTYPSIYTYATLLPATYNSIINPVIYAFRNQEI 308
Query: 305 QKVLWAVCCCCSSSKIPFRSRSPSDV 330
QK L +CC C S + R+RSPSDV
Sbjct: 309 QKALCLICCGCIPSSLAQRARSPSDV 334
>gi|7305013 lysophosphatidic acid receptor 2 [Homo sapiens]
Length = 351
Score = 134 bits (336), Expect = 1e-31
Identities = 96/285 (33%), Positives = 149/285 (52%), Gaps = 18/285 (6%)
Query: 44 DVVLCISGTLVSC----ENALVVAIIVGTPAFRAPMFLLVGSLAVADLLAGLG---LVLH 96
DVV+ G VS N LV+A I F P++ L+G+LA ADL AG+ L+ H
Sbjct: 32 DVVVVALGLTVSVLVLLTNLLVIAAIASNRRFHQPIYYLLGNLAAADLFAGVAYLFLMFH 91
Query: 97 FAAVFCIGSAEMSLVLVGVLAMAFTASIGSLLAITVDRYLSLYNALTYYSETTVTRTYVM 156
S E + G+L + TAS+ +LLAI V+R+ S+ A+ +S R ++
Sbjct: 92 TGPRTARLSLEGWFLRQGLLDTSLTASVATLLAIAVERHRSVM-AVQLHSRLPRGRVVML 150
Query: 157 LALVWGGALGLGLLPVLAWNCLDGLTTCGVVYP-LSKNHLVVLAIAFFMVFGIMLQLYAQ 215
+ VW ALGLGLLP +W+CL L C + P LS+++L V A++ +VF +M+ +Y +
Sbjct: 151 IVGVWVAALGLGLLPAHSWHCLCALDRCSRMAPLLSRSYLAVWALSSLLVFLLMVAVYTR 210
Query: 216 ICRIVCRHAQQIALQRHLLPASHYVATRKG-IATLAVVLGAFAACWLPFTVYCLLG---- 270
I V R Q++A H+ Y T + T+ ++LGAF CW P V LL
Sbjct: 211 IFFYVRRRVQRMA--EHVSCHPRYRETTLSLVKTVVIILGAFVVCWTPGQVVLLLDGLGC 268
Query: 271 -DAHSPPLYTYLTLLPATYNSMINPIIYAFRNQDVQKVLWAVCCC 314
+ + Y LL A NS++N +Y+ R+ ++++ + CC
Sbjct: 269 ESCNVLAVEKYFLLL-AEANSLVNAAVYSCRDAEMRRTFRRLLCC 312
>gi|13540517 endothelial differentiation, sphingolipid
G-protein-coupled receptor, 8 [Homo sapiens]
Length = 398
Score = 132 bits (332), Expect = 4e-31
Identities = 102/291 (35%), Positives = 148/291 (50%), Gaps = 26/291 (8%)
Query: 44 DVVLCISG-TLVSCENALVVAIIVGTPAFRAPMFLLVGSLAVADLLAGLGLVLHFAAVFC 102
D V+C++ + EN V+ ++ P F APMFLL+GSL ++DLLAG + A +
Sbjct: 39 DAVVCLAVCAFIVLENLAVLLVLGRHPRFHAPMFLLLGSLTLSDLLAGAA---YAANILL 95
Query: 103 IGSAEMSL------VLVGVLAMAFTASIGSLLAITVDRYLSLYNALTYYSETTVTRTYVM 156
G + L G + +A TAS+ SLLAI ++R L++ ++ RT M
Sbjct: 96 SGPLTLKLSPALWFAREGGVFVALTASVLSLLAIALERSLTMARRGPA-PVSSRGRTLAM 154
Query: 157 LALVWGGALGLGLLPVLAWNCLDGLTTCGVVYPL-SKNHLVVLAIAFFMVFGIMLQLYAQ 215
A WG +L LGLLP L WNCL L C V PL +K +++ +AF + + LYA+
Sbjct: 155 AAAAWGVSLLLGLLPALGWNCLGRLDACSTVLPLYAKAYVLFCVLAFVGILAAICALYAR 214
Query: 216 ICRIVCRHAQQIALQRHLLPASHYVATRKG-----IATLAVVLGAFAACWLPFTVYCLLG 270
I V +A+++ + + A RK + TL+VVL AF ACW P + LL
Sbjct: 215 IYCQVRANARRLPARPGTAGTTSTRARRKPRSLALLRTLSVVLLAFVACWGPLFLLLLLD 274
Query: 271 DAHSPPLYTYLTLLP-------ATYNSMINPIIYAFRNQDVQKVLWAVCCC 314
A P T LL A NS++NPIIY N+D++ L + CC
Sbjct: 275 VA--CPARTCPVLLQADPFLGLAMANSLLNPIIYTLTNRDLRHALLRLVCC 323
>gi|6912348 lysophosphatidic acid receptor 3 [Homo sapiens]
Length = 353
Score = 131 bits (329), Expect = 9e-31
Identities = 98/307 (31%), Positives = 154/307 (50%), Gaps = 32/307 (10%)
Query: 45 VVLCISGTL----VSCENALVVAIIVGTPAFRAPMFLLVGSLAVADLLAGLGLVLHFAAV 100
+VLC+ GT + N+LV+A ++ F P + L+ +LA AD AG+ V +
Sbjct: 32 IVLCV-GTFFCLFIFFSNSLVIAAVIKNRKFHFPFYYLLANLAAADFFAGIAYVF---LM 87
Query: 101 FCIGSAEMSLVL------VGVLAMAFTASIGSLLAITVDRYLSLYNALTYYSETTVTRTY 154
F G +L + G+L + TAS+ +LL I V+R++S+ + +S T R
Sbjct: 88 FNTGPVSKTLTVNRWFLRQGLLDSSLTASLTNLLVIAVERHMSIMR-MRVHSNLTKKRVT 146
Query: 155 VMLALVWGGALGLGLLPVLAWNCLDGLTTCGVVYPL-SKNHLVVLAIAFFMVFGIMLQLY 213
+++ LVW A+ +G +P L WNCL ++ C + P+ S+++LV ++ M F IM+ +Y
Sbjct: 147 LLILLVWAIAIFMGAVPTLGWNCLCNISACSSLAPIYSRSYLVFWTVSNLMAFLIMVVVY 206
Query: 214 AQICRIVCRHAQQIALQRHLLPA-SHYVATRKGIATLAVVLGAFAACWLPFTVYCLL--- 269
+I V R L H + S K + T+ VLGAF CW P V LL
Sbjct: 207 LRIYVYVKRKTN--VLSPHTSGSISRRRTPMKLMKTVMTVLGAFVVCWTPGLVVLLLDGL 264
Query: 270 -----GDAHSPPLYTYLTLLPATYNSMINPIIYAFRNQDVQKVLWAVCCCCSSSKIPFR- 323
G H + L LL NS++NPIIY+++++D+ + + CC S R
Sbjct: 265 NCRQCGVQHVKRWFLLLALL----NSVVNPIIYSYKDEDMYGTMKKMICCFSQENPERRP 320
Query: 324 SRSPSDV 330
SR PS V
Sbjct: 321 SRIPSTV 327
>gi|134244587 endothelial differentiation, sphingolipid
G-protein-coupled receptor, 5 [Homo sapiens]
Length = 353
Score = 127 bits (318), Expect = 2e-29
Identities = 91/280 (32%), Positives = 140/280 (50%), Gaps = 35/280 (12%)
Query: 42 AWDVVLCISGTLVSCENALVVAIIVGTPAFRAPMFLLVGSLAVADLLAGLGLVLHFAAVF 101
A+ V+LC + + EN LV+ + F + M+L +G+LA +DLLAG+ V A
Sbjct: 38 AFIVILCCA---IVVENLLVLIAVARNSKFHSAMYLFLGNLAASDLLAGVAFV---ANTL 91
Query: 102 CIGSAEMSLVLV------GVLAMAFTASIGSLLAITVDRYLSLYNALTYYSETTVTRTYV 155
GS + L V G + +AS+ SLLAI ++R++++ Y S+ + R +
Sbjct: 92 LSGSVTLRLTPVQWFAREGSAFITLSASVFSLLAIAIERHVAIAKVKLYGSDKSC-RMLL 150
Query: 156 MLALVWGGALGLGLLPVLAWNCLDGLTTCGVVYPLSKNHLVVLAIAFFMVFGIMLQLYAQ 215
++ W +L LG LP+L WNCL L C V PL H V+ + F + I+L + A
Sbjct: 151 LIGASWLISLVLGGLPILGWNCLGHLEACSTVLPLYAKHYVLCVVTIFSI--ILLAIVAL 208
Query: 216 ICRIVC----RHAQQIALQRHLLPASHYVATRKGIATLAVVLGAFAACWLPFTVYCLLGD 271
RI C HA A Q L + T+ +VLG F CWLP LL
Sbjct: 209 YVRIYCVVRSSHADMAAPQTLAL-----------LKTVTIVLGVFIVCWLPAFSILLLDY 257
Query: 272 A---HSPPLY--TYLTLLPATYNSMINPIIYAFRNQDVQK 306
A HS P+ + +T NS++NP+IY +R++D+++
Sbjct: 258 ACPVHSCPILYKAHYFFAVSTLNSLLNPVIYTWRSRDLRR 297
>gi|13027636 sphingosine-1-phosphate receptor 1 [Homo sapiens]
Length = 382
Score = 126 bits (317), Expect = 2e-29
Identities = 84/290 (28%), Positives = 150/290 (51%), Gaps = 17/290 (5%)
Query: 39 SPKAWDVVLCISGTLVSCENALVVAIIVGTPAFRAPMFLLVGSLAVADLLAGLG----LV 94
S K VV + + EN V+ I T F PM+ +G+LA++DLLAG+ L+
Sbjct: 44 SIKLTSVVFILICCFIILENIFVLLTIWKTKKFHRPMYYFIGNLALSDLLAGVAYTANLL 103
Query: 95 LHFAAVFCIGSAEMSLVLVGVLAMAFTASIGSLLAITVDRYLSLYNALTYYSETTVTRTY 154
L A + + A+ L G + +A +AS+ SLLAI ++RY+++ + ++ + R +
Sbjct: 104 LSGATTYKLTPAQWFL-REGSMFVALSASVFSLLAIAIERYITMLK-MKLHNGSNNFRLF 161
Query: 155 VMLALVWGGALGLGLLPVLAWNCLDGLTTCGVVYPLSKNHLVVLAIAFFMVFGI-MLQLY 213
++++ W +L LG LP++ WNC+ L++C V PL H ++ F + + ++ LY
Sbjct: 162 LLISACWVISLILGGLPIMGWNCISALSSCSTVLPLYHKHYILFCTTVFTLLLLSIVILY 221
Query: 214 AQICRIVCRHAQQIALQRHLLPASHYVATRKGIA---TLAVVLGAFAACWLPFTVYCLLG 270
+I +V ++++ ++++ AS ++ K +A T+ +VL F ACW P + LL
Sbjct: 222 CRIYSLVRTRSRRLTFRKNISKASR--SSEKSLALLKTVIIVLSVFIACWAPLFILLLLD 279
Query: 271 DAHSPPLYTYL-----TLLPATYNSMINPIIYAFRNQDVQKVLWAVCCCC 315
L L+ A NS NPIIY N+++++ + CC
Sbjct: 280 VGCKVKTCDILFRAEYFLVLAVLNSGTNPIIYTLTNKEMRRAFIRIMSCC 329
>gi|16950638 lysophosphatidic acid receptor 1 [Homo sapiens]
Length = 364
Score = 122 bits (307), Expect = 3e-28
Identities = 84/282 (29%), Positives = 144/282 (51%), Gaps = 22/282 (7%)
Query: 45 VVLCISGTLVSCENALVVAIIVGTPAFRAPMFLLVGSLAVADLLAGLGLVLHFAAVFCIG 104
+ +CI + N LV+ I F P++ L+ +LA AD AGL +F +F G
Sbjct: 57 ITVCI---FIMLANLLVMVAIYVNRRFHFPIYYLMANLAAADFFAGLA---YFYLMFNTG 110
Query: 105 ------SAEMSLVLVGVLAMAFTASIGSLLAITVDRYLSLYNALTYYSETTVTRTYVMLA 158
+ L+ G++ + TAS+ +LLAI ++R+++++ + ++ + R V++
Sbjct: 111 PNTRRLTVSTWLLRQGLIDTSLTASVANLLAIAIERHITVFR-MQLHTRMSNRRVVVVIV 169
Query: 159 LVWGGALGLGLLPVLAWNCLDGLTTCGVVYPL-SKNHLVVLAIAFFMVFGIMLQLYAQIC 217
++W A+ +G +P + WNC+ + C + PL S ++LV AI + F +M+ LYA I
Sbjct: 170 VIWTMAIVMGAIPSVGWNCICDIENCSNMAPLYSDSYLVFWAIFNLVTFVVMVVLYAHIF 229
Query: 218 RIVCRHAQQIALQRHLL-PASHYVATRKGIATLAVVLGAFAACWLPFTVYCLLGDAHSPP 276
V + + + RH P + + T+ +VLGAF CW P V LL D P
Sbjct: 230 GYV--RQRTMRMSRHSSGPRRNRDTMMSLLKTVVIVLGAFIICWTPGLVLLLL-DVCCPQ 286
Query: 277 ----LYTYLTLLPATYNSMINPIIYAFRNQDVQKVLWAVCCC 314
Y LL A +NS +NPIIY++R++++ + CC
Sbjct: 287 CDVLAYEKFFLLLAEFNSAMNPIIYSYRDKEMSATFRQILCC 328
>gi|16950636 lysophosphatidic acid receptor 1 [Homo sapiens]
Length = 364
Score = 122 bits (307), Expect = 3e-28
Identities = 84/282 (29%), Positives = 144/282 (51%), Gaps = 22/282 (7%)
Query: 45 VVLCISGTLVSCENALVVAIIVGTPAFRAPMFLLVGSLAVADLLAGLGLVLHFAAVFCIG 104
+ +CI + N LV+ I F P++ L+ +LA AD AGL +F +F G
Sbjct: 57 ITVCI---FIMLANLLVMVAIYVNRRFHFPIYYLMANLAAADFFAGLA---YFYLMFNTG 110
Query: 105 ------SAEMSLVLVGVLAMAFTASIGSLLAITVDRYLSLYNALTYYSETTVTRTYVMLA 158
+ L+ G++ + TAS+ +LLAI ++R+++++ + ++ + R V++
Sbjct: 111 PNTRRLTVSTWLLRQGLIDTSLTASVANLLAIAIERHITVFR-MQLHTRMSNRRVVVVIV 169
Query: 159 LVWGGALGLGLLPVLAWNCLDGLTTCGVVYPL-SKNHLVVLAIAFFMVFGIMLQLYAQIC 217
++W A+ +G +P + WNC+ + C + PL S ++LV AI + F +M+ LYA I
Sbjct: 170 VIWTMAIVMGAIPSVGWNCICDIENCSNMAPLYSDSYLVFWAIFNLVTFVVMVVLYAHIF 229
Query: 218 RIVCRHAQQIALQRHLL-PASHYVATRKGIATLAVVLGAFAACWLPFTVYCLLGDAHSPP 276
V + + + RH P + + T+ +VLGAF CW P V LL D P
Sbjct: 230 GYV--RQRTMRMSRHSSGPRRNRDTMMSLLKTVVIVLGAFIICWTPGLVLLLL-DVCCPQ 286
Query: 277 ----LYTYLTLLPATYNSMINPIIYAFRNQDVQKVLWAVCCC 314
Y LL A +NS +NPIIY++R++++ + CC
Sbjct: 287 CDVLAYEKFFLLLAEFNSAMNPIIYSYRDKEMSATFRQILCC 328
>gi|119508433 melanocortin 4 receptor [Homo sapiens]
Length = 332
Score = 115 bits (287), Expect = 7e-26
Identities = 80/288 (27%), Positives = 133/288 (46%), Gaps = 47/288 (16%)
Query: 51 GTLVSCENALVVAIIVGTPAFRAPMFLLVGSLAVADLLAGLGLVLHFAAVFCIGSAEMSL 110
G + EN LV+ I +PM+ + SLAVAD+L + + + S +
Sbjct: 55 GVISLLENILVIVAIAKNKNLHSPMYFFICSLAVADMLVSVSNGSETIVITLLNSTDTDA 114
Query: 111 ---------VLVGVLAMAFTASIGSLLAITVDRYLSLYNALTYYSETTVTRTYVMLALVW 161
V+ V+ + ASI SLL+I VDRY +++ AL Y++ TV R ++++ +W
Sbjct: 115 QSFTVNIDNVIDSVICSSLLASICSLLSIAVDRYFTIFYALQYHNIMTVKRVGIIISCIW 174
Query: 162 GGALGLGLLPVLAWNCLDGLTTCGVVYPLSKNHLVVLAIAFFMVFGIMLQLYAQICRIVC 221
G+L ++Y S ++ L FF + +M LY + +
Sbjct: 175 AACTVSGIL--------------FIIYSDSSAVIICLITMFFTMLALMASLYVHMFLMAR 220
Query: 222 RHAQQIALQRHLLPASHYV---ATRKGIATLAVVLGAFAACWLPFTV------------Y 266
H ++IA +LP + + A KG TL +++G F CW PF + Y
Sbjct: 221 LHIKRIA----VLPGTGAIRQGANMKGAITLTILIGVFVVCWAPFFLHLIFYISCPQNPY 276
Query: 267 CLLGDAHSPPLYTYLTLLPATYNSMINPIIYAFRNQDVQKVLWAVCCC 314
C+ +H YL L+ NS+I+P+IYA R+Q+++K + CC
Sbjct: 277 CVCFMSH---FNLYLILIMC--NSIIDPLIYALRSQELRKTFKEIICC 319
>gi|5174535 melanocortin 5 receptor [Homo sapiens]
Length = 325
Score = 113 bits (283), Expect = 2e-25
Identities = 79/286 (27%), Positives = 136/286 (47%), Gaps = 42/286 (14%)
Query: 51 GTLVSCENALVVAIIVGTPAFRAPMFLLVGSLAVADLLAGLGLVLHFAAVFCIGSAEMSL 110
G + EN LV+ IV +PM+ V SLAVAD+L + ++ + + + +
Sbjct: 47 GVISLLENILVIGAIVKNKNLHSPMYFFVCSLAVADMLVSMSSAWETITIYLLNNKHLVI 106
Query: 111 ----------VLVGVLAMAFTASIGSLLAITVDRYLSLYNALTYYSETTVTRTYVMLALV 160
V ++ ++ AS+ SLLAI VDRY++++ AL Y+ T R+ ++A +
Sbjct: 107 ADAFVRHIDNVFDSMICISVVASMCSLLAIAVDRYVTIFYALRYHHIMTARRSGAIIAGI 166
Query: 161 WGGALGLGLLPVLAWNCLDGLTTCGVVYPLSKNHLVVLAIAFFMVFGIMLQLYAQICRIV 220
W G G++ +L Y S ++ L FF + +++ LY + +
Sbjct: 167 WAFCTGCGIVFIL--------------YSESTYVILCLISMFFAMLFLLVSLYIHMFLLA 212
Query: 221 CRHAQQIALQRHLLPASHYVATR---KGIATLAVVLGAFAACWLPFTVYCLLGDAHSPPL 277
H ++IA LP + R +G T+ ++LG F CW PF ++ L + L
Sbjct: 213 RTHVKRIA----ALPGASSARQRTSMQGAVTVTMLLGVFTVCWAPFFLHLTLMLSCPQNL 268
Query: 278 Y---------TYLTLLPATYNSMINPIIYAFRNQDVQKVLWAVCCC 314
Y YL L+ NS+++P+IYAFR+Q+++K + CC
Sbjct: 269 YCSRFMSHFNMYLILIMC--NSVMDPLIYAFRSQEMRKTFKEIICC 312
>gi|170671732 melanocortin 3 receptor [Homo sapiens]
Length = 323
Score = 112 bits (280), Expect = 5e-25
Identities = 85/297 (28%), Positives = 134/297 (45%), Gaps = 50/297 (16%)
Query: 51 GTLVSCENALVVAIIVGTPAFRAPMFLLVGSLAVADLLAGLGLVLHFAAVFCIGS----- 105
G + EN LV+ +V +PM+ + SLAVAD+L + L + + S
Sbjct: 49 GIVSLLENILVILAVVRNGNLHSPMYFFLCSLAVADMLVSVSNALETIMIAIVHSDYLTF 108
Query: 106 -----AEMSLVLVGVLAMAFTASIGSLLAITVDRYLSLYNALTYYSETTVTRTYVMLALV 160
M + ++ ++ ASI +LLAI VDRY++++ AL Y+S TV + ++
Sbjct: 109 EDQFIQHMDNIFDSMICISLVASICNLLAIAVDRYVTIFYALRYHSIMTVRKALTLI--- 165
Query: 161 WGGALGLGLLPVLAWNCLDGLTTCGVVYPLSKNHLVVLAIAFFMVFGIMLQLYAQICRIV 220
V W C +VY SK +V L FF + +M LY +
Sbjct: 166 -----------VAIWVCCGVCGVVFIVYSESKMVIVCLITMFFAMMLLMGTLYVHMFLFA 214
Query: 221 CRHAQQIALQRHLLPASHYVATR-----KGIATLAVVLGAFAACWLPFTV---------- 265
H ++IA LP + VA + KG T+ ++LG F CW PF +
Sbjct: 215 RLHVKRIA----ALPPADGVAPQQHSCMKGAVTITILLGVFIFCWAPFFLHLVLIITCPT 270
Query: 266 --YCLLGDAHSPPLYTYLTLLPATYNSMINPIIYAFRNQDVQKVLWAVCCCCSSSKI 320
YC+ AH TYL L+ NS+I+P+IYAFR+ +++ + C C+ +
Sbjct: 271 NPYCICYTAH---FNTYLVLIMC--NSVIDPLIYAFRSLELRNTFREILCGCNGMNL 322
>gi|4501951 adenosine A2b receptor [Homo sapiens]
Length = 332
Score = 112 bits (279), Expect = 6e-25
Identities = 87/277 (31%), Positives = 131/277 (47%), Gaps = 36/277 (12%)
Query: 58 NALVVAIIVGTPAFRAPMFLLVGSLAVADLLAGLGLVLHFAAVFCIGSAEM---SLVLVG 114
N LV A + + P + SLA AD+ GL + FA +G L L
Sbjct: 25 NVLVCAAVGTANTLQTPTNYFLVSLAAADVAVGL-FAIPFAITISLGFCTDFYGCLFLAC 83
Query: 115 VLAMAFTASIGSLLAITVDRYLSLYNALTYYSETTVTRTYVMLALVWGGALGLGLLPVLA 174
+ + +SI SLLA+ VDRYL++ L Y S T TR ++A++W A G+GL P L
Sbjct: 84 FVLVLTQSSIFSLLAVAVDRYLAICVPLRYKSLVTGTRARGVIAVLWVLAFGIGLTPFLG 143
Query: 175 WNCLDGLT-------------TCGVVYPLSKNHLVVLAIAFFMVFG-------IMLQLYA 214
WN D T +C +V L +N + + + +F FG IML +Y
Sbjct: 144 WNSKDSATNNCTEPWDGTTNESCCLVKCLFENVVPMSYMVYFNFFGCVLPPLLIMLVIYI 203
Query: 215 QICRIVCRHAQQIALQRHLLPASHYVATRK--GIATLAVVLGAFAACWLP------FTVY 266
+I + CR Q+ L H S R+ +LA+++G FA CWLP T++
Sbjct: 204 KIFLVACRQLQRTELMDH----SRTTLQREIHAAKSLAMIVGIFALCWLPVHAVNCVTLF 259
Query: 267 CLLGDAHSPPLYTYLTLLPATYNSMINPIIYAFRNQD 303
+ P + +L + NS++NPI+YA+RN+D
Sbjct: 260 QPAQGKNKPKWAMNMAILLSHANSVVNPIVYAYRNRD 296
>gi|4503459 sphingosine-1-phosphate receptor 4 precursor [Homo
sapiens]
Length = 384
Score = 108 bits (271), Expect = 5e-24
Identities = 90/276 (32%), Positives = 136/276 (49%), Gaps = 21/276 (7%)
Query: 53 LVSCENALVVAIIVGTPAFRAPMFLLVGSLAVADLLAGLG----LVLHFAAVFCIGSAEM 108
LV EN LV+A I R ++ + ++ ++DLL G ++L A F + A+
Sbjct: 59 LVVLENLLVLAAITSHMRSRRWVYYCLVNITLSDLLTGAAYLANVLLSGARTFRLAPAQW 118
Query: 109 SLVLVGVLAMAFTASIGSLLAITVDRYLSLYNALTYYSETTVTRTYVMLALVWGGALGLG 168
L G+L A AS SLL +R+ ++ + T +R Y + L W A LG
Sbjct: 119 FL-REGLLFTALAASTFSLLFTAGERFATMVRPVAESGATKTSRVYGFIGLCWLLAALLG 177
Query: 169 LLPVLAWNCLDGLTTCGVVYPL-SKNHLVVLAIAFFMVFGIMLQLYAQICRIVCRHAQQI 227
+LP+L WNCL C + PL SK +++ + F V ++ LY I R+V Q
Sbjct: 178 MLPLLGWNCLCAFDRCSSLLPLYSKRYILFCLVIFAGVLATIMGLYGAIFRLV-----QA 232
Query: 228 ALQRHLLPASHYVATRKGIATLAVVLGAFAACWLPFTVYCLLGDAHSPPLYT--YL---- 281
+ Q+ PA+ A R+ + T+ ++L AF CW P LL D L+ YL
Sbjct: 233 SGQKAPRPAARRKA-RRLLKTVLMILLAFLVCWGPL-FGLLLADVFGSNLWAQEYLRGMD 290
Query: 282 -TLLPATYNSMINPIIYAFRNQDV-QKVLWAVCCCC 315
L A NS +NPIIY+FR+++V + VL +CC C
Sbjct: 291 WILALAVLNSAVNPIIYSFRSREVCRAVLSFLCCGC 326
>gi|237681179 cannabinoid receptor 1 isoform a [Homo sapiens]
Length = 472
Score = 108 bits (270), Expect = 7e-24
Identities = 87/311 (27%), Positives = 148/311 (47%), Gaps = 29/311 (9%)
Query: 38 PSPKAWDVVLCIS-GTLVSCENALVVAIIVGTPAFRA-PMFLLVGSLAVADLLAGLGLVL 95
PS + VL ++ GT EN LV+ +I+ + + R P + +GSLAVADLL + V
Sbjct: 113 PSQQLAIAVLSLTLGTFTVLENLLVLCVILHSRSLRCRPSYHFIGSLAVADLLGSVIFVY 172
Query: 96 HFAAVFCI---GSAEMSLVLVGVLAMAFTASIGSLLAITVDRYLSLYNALTYYSETTVTR 152
F S + L +G + +FTAS+GSL +DRY+S++ L Y T +
Sbjct: 173 SFIDFHVFHRKDSRNVFLFKLGGVTASFTASVGSLFLTAIDRYISIHRPLAYKRIVTRPK 232
Query: 153 TYVMLALVWGGALGLGLLPVLAWNCLDGLTTCGVVYP-LSKNHL-----VVLAIAFFMVF 206
V L+W A+ + +LP+L WNC + C ++P + + +L V + F+V+
Sbjct: 233 AVVAFCLMWTIAIVIAVLPLLGWNCEKLQSVCSDIFPHIDETYLMFWIGVTSVLLLFIVY 292
Query: 207 G---IMLQLYAQICRIVCRHAQQIALQRHLLPASHYVATRKGIA--------TLAVVLGA 255
I+ + ++ R++ R Q+ ++ H TR A TL ++L
Sbjct: 293 AYMYILWKAHSHAVRMIQRGTQK-SIIIHTSEDGKVQVTRPDQARMDIRLAKTLVLILVV 351
Query: 256 FAACW---LPFTVYCLLGDAHS--PPLYTYLTLLPATYNSMINPIIYAFRNQDVQKVLWA 310
CW L VY + G + ++ + ++L NS +NPIIYA R++D++ +
Sbjct: 352 LIICWGPLLAIMVYDVFGKMNKLIKTVFAFCSML-CLLNSTVNPIIYALRSKDLRHAFRS 410
Query: 311 VCCCCSSSKIP 321
+ C + P
Sbjct: 411 MFPSCEGTAQP 421
>gi|237681175 cannabinoid receptor 1 isoform a [Homo sapiens]
Length = 472
Score = 108 bits (270), Expect = 7e-24
Identities = 87/311 (27%), Positives = 148/311 (47%), Gaps = 29/311 (9%)
Query: 38 PSPKAWDVVLCIS-GTLVSCENALVVAIIVGTPAFRA-PMFLLVGSLAVADLLAGLGLVL 95
PS + VL ++ GT EN LV+ +I+ + + R P + +GSLAVADLL + V
Sbjct: 113 PSQQLAIAVLSLTLGTFTVLENLLVLCVILHSRSLRCRPSYHFIGSLAVADLLGSVIFVY 172
Query: 96 HFAAVFCI---GSAEMSLVLVGVLAMAFTASIGSLLAITVDRYLSLYNALTYYSETTVTR 152
F S + L +G + +FTAS+GSL +DRY+S++ L Y T +
Sbjct: 173 SFIDFHVFHRKDSRNVFLFKLGGVTASFTASVGSLFLTAIDRYISIHRPLAYKRIVTRPK 232
Query: 153 TYVMLALVWGGALGLGLLPVLAWNCLDGLTTCGVVYP-LSKNHL-----VVLAIAFFMVF 206
V L+W A+ + +LP+L WNC + C ++P + + +L V + F+V+
Sbjct: 233 AVVAFCLMWTIAIVIAVLPLLGWNCEKLQSVCSDIFPHIDETYLMFWIGVTSVLLLFIVY 292
Query: 207 G---IMLQLYAQICRIVCRHAQQIALQRHLLPASHYVATRKGIA--------TLAVVLGA 255
I+ + ++ R++ R Q+ ++ H TR A TL ++L
Sbjct: 293 AYMYILWKAHSHAVRMIQRGTQK-SIIIHTSEDGKVQVTRPDQARMDIRLAKTLVLILVV 351
Query: 256 FAACW---LPFTVYCLLGDAHS--PPLYTYLTLLPATYNSMINPIIYAFRNQDVQKVLWA 310
CW L VY + G + ++ + ++L NS +NPIIYA R++D++ +
Sbjct: 352 LIICWGPLLAIMVYDVFGKMNKLIKTVFAFCSML-CLLNSTVNPIIYALRSKDLRHAFRS 410
Query: 311 VCCCCSSSKIP 321
+ C + P
Sbjct: 411 MFPSCEGTAQP 421
>gi|237681173 cannabinoid receptor 1 isoform a [Homo sapiens]
Length = 472
Score = 108 bits (270), Expect = 7e-24
Identities = 87/311 (27%), Positives = 148/311 (47%), Gaps = 29/311 (9%)
Query: 38 PSPKAWDVVLCIS-GTLVSCENALVVAIIVGTPAFRA-PMFLLVGSLAVADLLAGLGLVL 95
PS + VL ++ GT EN LV+ +I+ + + R P + +GSLAVADLL + V
Sbjct: 113 PSQQLAIAVLSLTLGTFTVLENLLVLCVILHSRSLRCRPSYHFIGSLAVADLLGSVIFVY 172
Query: 96 HFAAVFCI---GSAEMSLVLVGVLAMAFTASIGSLLAITVDRYLSLYNALTYYSETTVTR 152
F S + L +G + +FTAS+GSL +DRY+S++ L Y T +
Sbjct: 173 SFIDFHVFHRKDSRNVFLFKLGGVTASFTASVGSLFLTAIDRYISIHRPLAYKRIVTRPK 232
Query: 153 TYVMLALVWGGALGLGLLPVLAWNCLDGLTTCGVVYP-LSKNHL-----VVLAIAFFMVF 206
V L+W A+ + +LP+L WNC + C ++P + + +L V + F+V+
Sbjct: 233 AVVAFCLMWTIAIVIAVLPLLGWNCEKLQSVCSDIFPHIDETYLMFWIGVTSVLLLFIVY 292
Query: 207 G---IMLQLYAQICRIVCRHAQQIALQRHLLPASHYVATRKGIA--------TLAVVLGA 255
I+ + ++ R++ R Q+ ++ H TR A TL ++L
Sbjct: 293 AYMYILWKAHSHAVRMIQRGTQK-SIIIHTSEDGKVQVTRPDQARMDIRLAKTLVLILVV 351
Query: 256 FAACW---LPFTVYCLLGDAHS--PPLYTYLTLLPATYNSMINPIIYAFRNQDVQKVLWA 310
CW L VY + G + ++ + ++L NS +NPIIYA R++D++ +
Sbjct: 352 LIICWGPLLAIMVYDVFGKMNKLIKTVFAFCSML-CLLNSTVNPIIYALRSKDLRHAFRS 410
Query: 311 VCCCCSSSKIP 321
+ C + P
Sbjct: 411 MFPSCEGTAQP 421
>gi|237681067 cannabinoid receptor 1 isoform a [Homo sapiens]
Length = 472
Score = 108 bits (270), Expect = 7e-24
Identities = 87/311 (27%), Positives = 148/311 (47%), Gaps = 29/311 (9%)
Query: 38 PSPKAWDVVLCIS-GTLVSCENALVVAIIVGTPAFRA-PMFLLVGSLAVADLLAGLGLVL 95
PS + VL ++ GT EN LV+ +I+ + + R P + +GSLAVADLL + V
Sbjct: 113 PSQQLAIAVLSLTLGTFTVLENLLVLCVILHSRSLRCRPSYHFIGSLAVADLLGSVIFVY 172
Query: 96 HFAAVFCI---GSAEMSLVLVGVLAMAFTASIGSLLAITVDRYLSLYNALTYYSETTVTR 152
F S + L +G + +FTAS+GSL +DRY+S++ L Y T +
Sbjct: 173 SFIDFHVFHRKDSRNVFLFKLGGVTASFTASVGSLFLTAIDRYISIHRPLAYKRIVTRPK 232
Query: 153 TYVMLALVWGGALGLGLLPVLAWNCLDGLTTCGVVYP-LSKNHL-----VVLAIAFFMVF 206
V L+W A+ + +LP+L WNC + C ++P + + +L V + F+V+
Sbjct: 233 AVVAFCLMWTIAIVIAVLPLLGWNCEKLQSVCSDIFPHIDETYLMFWIGVTSVLLLFIVY 292
Query: 207 G---IMLQLYAQICRIVCRHAQQIALQRHLLPASHYVATRKGIA--------TLAVVLGA 255
I+ + ++ R++ R Q+ ++ H TR A TL ++L
Sbjct: 293 AYMYILWKAHSHAVRMIQRGTQK-SIIIHTSEDGKVQVTRPDQARMDIRLAKTLVLILVV 351
Query: 256 FAACW---LPFTVYCLLGDAHS--PPLYTYLTLLPATYNSMINPIIYAFRNQDVQKVLWA 310
CW L VY + G + ++ + ++L NS +NPIIYA R++D++ +
Sbjct: 352 LIICWGPLLAIMVYDVFGKMNKLIKTVFAFCSML-CLLNSTVNPIIYALRSKDLRHAFRS 410
Query: 311 VCCCCSSSKIP 321
+ C + P
Sbjct: 411 MFPSCEGTAQP 421
>gi|38683844 cannabinoid receptor 1 isoform a [Homo sapiens]
Length = 472
Score = 108 bits (270), Expect = 7e-24
Identities = 87/311 (27%), Positives = 148/311 (47%), Gaps = 29/311 (9%)
Query: 38 PSPKAWDVVLCIS-GTLVSCENALVVAIIVGTPAFRA-PMFLLVGSLAVADLLAGLGLVL 95
PS + VL ++ GT EN LV+ +I+ + + R P + +GSLAVADLL + V
Sbjct: 113 PSQQLAIAVLSLTLGTFTVLENLLVLCVILHSRSLRCRPSYHFIGSLAVADLLGSVIFVY 172
Query: 96 HFAAVFCI---GSAEMSLVLVGVLAMAFTASIGSLLAITVDRYLSLYNALTYYSETTVTR 152
F S + L +G + +FTAS+GSL +DRY+S++ L Y T +
Sbjct: 173 SFIDFHVFHRKDSRNVFLFKLGGVTASFTASVGSLFLTAIDRYISIHRPLAYKRIVTRPK 232
Query: 153 TYVMLALVWGGALGLGLLPVLAWNCLDGLTTCGVVYP-LSKNHL-----VVLAIAFFMVF 206
V L+W A+ + +LP+L WNC + C ++P + + +L V + F+V+
Sbjct: 233 AVVAFCLMWTIAIVIAVLPLLGWNCEKLQSVCSDIFPHIDETYLMFWIGVTSVLLLFIVY 292
Query: 207 G---IMLQLYAQICRIVCRHAQQIALQRHLLPASHYVATRKGIA--------TLAVVLGA 255
I+ + ++ R++ R Q+ ++ H TR A TL ++L
Sbjct: 293 AYMYILWKAHSHAVRMIQRGTQK-SIIIHTSEDGKVQVTRPDQARMDIRLAKTLVLILVV 351
Query: 256 FAACW---LPFTVYCLLGDAHS--PPLYTYLTLLPATYNSMINPIIYAFRNQDVQKVLWA 310
CW L VY + G + ++ + ++L NS +NPIIYA R++D++ +
Sbjct: 352 LIICWGPLLAIMVYDVFGKMNKLIKTVFAFCSML-CLLNSTVNPIIYALRSKDLRHAFRS 410
Query: 311 VCCCCSSSKIP 321
+ C + P
Sbjct: 411 MFPSCEGTAQP 421
>gi|237681065 cannabinoid receptor 1 isoform b [Homo sapiens]
Length = 439
Score = 108 bits (270), Expect = 7e-24
Identities = 87/311 (27%), Positives = 148/311 (47%), Gaps = 29/311 (9%)
Query: 38 PSPKAWDVVLCIS-GTLVSCENALVVAIIVGTPAFRA-PMFLLVGSLAVADLLAGLGLVL 95
PS + VL ++ GT EN LV+ +I+ + + R P + +GSLAVADLL + V
Sbjct: 80 PSQQLAIAVLSLTLGTFTVLENLLVLCVILHSRSLRCRPSYHFIGSLAVADLLGSVIFVY 139
Query: 96 HFAAVFCI---GSAEMSLVLVGVLAMAFTASIGSLLAITVDRYLSLYNALTYYSETTVTR 152
F S + L +G + +FTAS+GSL +DRY+S++ L Y T +
Sbjct: 140 SFIDFHVFHRKDSRNVFLFKLGGVTASFTASVGSLFLTAIDRYISIHRPLAYKRIVTRPK 199
Query: 153 TYVMLALVWGGALGLGLLPVLAWNCLDGLTTCGVVYP-LSKNHL-----VVLAIAFFMVF 206
V L+W A+ + +LP+L WNC + C ++P + + +L V + F+V+
Sbjct: 200 AVVAFCLMWTIAIVIAVLPLLGWNCEKLQSVCSDIFPHIDETYLMFWIGVTSVLLLFIVY 259
Query: 207 G---IMLQLYAQICRIVCRHAQQIALQRHLLPASHYVATRKGIA--------TLAVVLGA 255
I+ + ++ R++ R Q+ ++ H TR A TL ++L
Sbjct: 260 AYMYILWKAHSHAVRMIQRGTQK-SIIIHTSEDGKVQVTRPDQARMDIRLAKTLVLILVV 318
Query: 256 FAACW---LPFTVYCLLGDAHS--PPLYTYLTLLPATYNSMINPIIYAFRNQDVQKVLWA 310
CW L VY + G + ++ + ++L NS +NPIIYA R++D++ +
Sbjct: 319 LIICWGPLLAIMVYDVFGKMNKLIKTVFAFCSML-CLLNSTVNPIIYALRSKDLRHAFRS 377
Query: 311 VCCCCSSSKIP 321
+ C + P
Sbjct: 378 MFPSCEGTAQP 388
>gi|38788193 sphingosine-1-phosphate receptor 3 [Homo sapiens]
Length = 378
Score = 107 bits (267), Expect = 1e-23
Identities = 78/285 (27%), Positives = 140/285 (49%), Gaps = 29/285 (10%)
Query: 45 VVLCISGTLVSCENALVVAIIVGTPAFRAPMFLLVGSLAVADLLAGLGLVLHFAAVFCIG 104
+V+C + + EN +V+ I F M+ +G+LA+ DLLAG+ ++ + G
Sbjct: 47 LVIC---SFIVLENLMVLIAIWKNNKFHNRMYFFIGNLALCDLLAGIAYKVN---ILMSG 100
Query: 105 SAEMSL------VLVGVLAMAFTASIGSLLAITVDRYLSLYNALTYYSETTVTRTYVMLA 158
SL + G + +A AS SLLAI ++R+L++ + Y R ++++
Sbjct: 101 KKTFSLSPTVWFLREGSMFVALGASTCSLLAIAIERHLTMIK-MRPYDANKRHRVFLLIG 159
Query: 159 LVWGGALGLGLLPVLAWNCLDGLTTCGVVYPL-SKNHLVVLAIAFFMVFGIMLQLYAQIC 217
+ W A LG LP+L WNCL L C + PL SK ++ F + ++ LYA+I
Sbjct: 160 MCWLIAFTLGALPILGWNCLHNLPDCSTILPLYSKKYIAFCISIFTAILVTIVILYARIY 219
Query: 218 RIVCRHAQQIALQRHLLPASHYVATRKG--IATLAVVLGAFAACWLPFTVYCLLGDA--- 272
+V ++++ A+H + R + T+ +V+ F ACW P + L+ A
Sbjct: 220 FLVKSSSRKV--------ANHNNSERSMALLRTVVIVVSVFIACWSPLFILFLIDVACRV 271
Query: 273 -HSPPLY-TYLTLLPATYNSMINPIIYAFRNQDVQKVLWAVCCCC 315
P L+ ++ A NS +NP+IY ++++++ + + C C
Sbjct: 272 QACPILFKAQWFIVLAVLNSAMNPVIYTLASKEMRRAFFRLVCNC 316
>gi|4502929 cannabinoid receptor 2 (macrophage) [Homo sapiens]
Length = 360
Score = 102 bits (253), Expect = 6e-22
Identities = 79/282 (28%), Positives = 135/282 (47%), Gaps = 19/282 (6%)
Query: 38 PSPKAWDVVLCISGTLVSCENALVVAIIVGTPAFRA-PMFLLVGSLAVADLLAGLGLV-- 94
P A V+ + G L + EN V+ +I+ + R P +L +GSLA AD LA +
Sbjct: 31 PQKTAVAVLCTLLGLLSALENVAVLYLILSSHQLRRKPSYLFIGSLAGADFLASVVFACS 90
Query: 95 -LHFAAVFCIGSAEMSLVLVGVLAMAFTASIGSLLAITVDRYLSLYNALTYYSETTVTRT 153
++F + S + L+ +G + M FTAS+GSLL +DRYL L +Y + T R
Sbjct: 91 FVNFHVFHGVDSKAVFLLKIGSVTMTFTASVGSLLLTAIDRYLCLRYPPSYKALLTRGRA 150
Query: 154 YVMLALVWGGALGLGLLPVLAWNCLDGLTTCGVVYPLSKNHLVVLAIAFF-MVFGIMLQL 212
V L ++W + + LP++ W C C ++PL N ++ + F +F ++
Sbjct: 151 LVTLGIMWVLSALVSYLPLMGWTCCP--RPCSELFPLIPNDYLLSWLLFIAFLFSGIIYT 208
Query: 213 YAQICRIVCRHAQQIA-LQRHLLPASHYVATRKGIA-TLAVVLGAFAACWLPFTVYCLLG 270
Y + +H ++ Q +P + +A TL +VL CW P V L+
Sbjct: 209 YGHVLWKAHQHVASLSGHQDRQVPGMARMRLDVRLAKTLGLVLAVLLICWFP--VLALMA 266
Query: 271 DAHSPPL-------YTYLTLLPATYNSMINPIIYAFRNQDVQ 305
+ + L + + ++L NSM+NP+IYA R+ +++
Sbjct: 267 HSLATTLSDQVKKAFAFCSML-CLINSMVNPVIYALRSGEIR 307
>gi|4505127 melanocortin 2 receptor [Homo sapiens]
Length = 297
Score = 98.6 bits (244), Expect = 7e-21
Identities = 75/275 (27%), Positives = 131/275 (47%), Gaps = 39/275 (14%)
Query: 57 ENALVVAIIVGTPAFRAPMFLLVGSLAVADLLAGLGLVLHFAAVFCI--------GSAEM 108
EN +V+ + +APM+ + SLA++D+L L +L + GS E
Sbjct: 41 ENLIVLLAVFKNKNLQAPMYFFICSLAISDMLGSLYKILENILIILRNMGYLKPRGSFET 100
Query: 109 SL--VLVGVLAMAFTASIGSLLAITVDRYLSLYNALTYYSETTVTRTYVMLALVWGGALG 166
+ ++ + ++ SI SL I DRY+++++AL Y+S T+ RT V+L ++W G
Sbjct: 101 TADDIIDSLFVLSLLGSIFSLSVIAADRYITIFHALRYHSIVTMRRTVVVLTVIWTFCTG 160
Query: 167 LGLLPVLAWNCLDGLTTCGVVYPLSKNHLVVLAIAFFMVFGIMLQLYAQICRIVCRHAQQ 226
G+ V+ + + + T ++PL +VF +L LY + + H ++
Sbjct: 161 TGITMVIFSHHVPTVITFTSLFPL------------MLVF--ILCLYVHMFLLARSHTRK 206
Query: 227 IALQRHLLPASHYVATRKGIATLAVVLGAFAACWLPFTVYCLLGD--AHSPPLYTYLTLL 284
I+ LP A KG TL ++LG F CW PF ++ LL +P Y++L
Sbjct: 207 IS----TLPR----ANMKGAITLTILLGVFIFCWAPFVLHVLLMTFCPSNPYCACYMSLF 258
Query: 285 PAT-----YNSMINPIIYAFRNQDVQKVLWAVCCC 314
N++I+P IYAFR+ +++ + C
Sbjct: 259 QVNGMLIMCNAVIDPFIYAFRSPELRDAFKKMIFC 293
>gi|4501953 adenosine A3 receptor isoform 2 [Homo sapiens]
Length = 318
Score = 97.8 bits (242), Expect = 1e-20
Identities = 79/273 (28%), Positives = 131/273 (47%), Gaps = 17/273 (6%)
Query: 58 NALVVAIIVGTPAFRAPMFLLVGSLAVADLLAGLGLVLHFAAVFCIGSAE--MSLVLVGV 115
N LV+ ++ P+ + F + SLA+AD+ G+ LV+ A V +G S + +
Sbjct: 30 NVLVICVVKLNPSLQTTTFYFIVSLALADIAVGV-LVMPLAIVVSLGITIHFYSCLFMTC 88
Query: 116 LAMAFT-ASIGSLLAITVDRYLSLYNALTYYSETTVTRTYVMLALVWGGALGLGLLPVLA 174
L + FT ASI SLLAI VDRYL + + Y TT R ++ L L W + +GL P+
Sbjct: 89 LLLIFTHASIMSLLAIAVDRYLRVKLTVRYKRVTTHRRIWLALGLCWLVSFLVGLTPMFG 148
Query: 175 WNCL--------DGLTTCGVVYPLSKNHLVVLAIA--FFMVFGIMLQLYAQICRIVCRHA 224
WN +C V + +++V + F+ +M +Y I I+ R+
Sbjct: 149 WNMKLTSEYHRNVTFLSCQFVSVMRMDYMVYFSFLTWIFIPLVVMCAIYLDIFYII-RNK 207
Query: 225 QQIALQRHLLPASHYVATRKGIATLAVVLGAFAACWLPFTVY-CLL-GDAHSPPLYTYLT 282
+ L + Y K +L +VL FA WLP ++ C++ + P L Y+
Sbjct: 208 LSLNLSNSKETGAFYGREFKTAKSLFLVLFLFALSWLPLSIINCIIYFNGEVPQLVLYMG 267
Query: 283 LLPATYNSMINPIIYAFRNQDVQKVLWAVCCCC 315
+L + NSM+NPI+YA++ + ++ + C
Sbjct: 268 ILLSHANSMMNPIVYAYKIKKFKETYLLILKAC 300
>gi|193083134 melanocortin 1 receptor [Homo sapiens]
Length = 317
Score = 97.1 bits (240), Expect = 2e-20
Identities = 78/281 (27%), Positives = 126/281 (44%), Gaps = 31/281 (11%)
Query: 51 GTLVSCENALVVAIIVGTPAFRAPMFLLVGSLAVADLLAGLGLVLHFAAVFCIGSA---- 106
G + ENALVVA I +PM+ + LA++DLL VL A + + +
Sbjct: 49 GLVSLVENALVVATIAKNRNLHSPMYCFICCLALSDLLVSGSNVLETAVILLLEAGALVA 108
Query: 107 ------EMSLVLVGVLAMAFTASIGSLLAITVDRYLSLYNALTYYSETTVTRTYVMLALV 160
++ V+ + + +S+ L AI VDRY+S++ AL Y+S T+ R +A +
Sbjct: 109 RAAVLQQLDNVIDVITCSSMLSSLCFLGAIAVDRYISIFYALRYHSIVTLPRARRAVAAI 168
Query: 161 WGGALGLGLLPVLAWNCLDGLTTCGVVYPLSKNHLVVLAIAFFMVFGIMLQLYAQICRIV 220
W ++ +T + Y L+ L + F + +M LY +
Sbjct: 169 WVASV--------------VFSTLFIAYYDHVAVLLCLVVFFLAMLVLMAVLYVHMLARA 214
Query: 221 CRHAQQIALQRHLLPASHYVATRKGIATLAVVLGAFAACWLPFTVY---CLLGDAHSPPL 277
C+HAQ IA H KG TL ++LG F CW PF ++ +L H
Sbjct: 215 CQHAQGIARLHKRQRPVHQGFGLKGAVTLTILLGIFFLCWGPFFLHLTLIVLCPEHPTCG 274
Query: 278 YTY----LTLLPATYNSMINPIIYAFRNQDVQKVLWAVCCC 314
+ L L N++I+P+IYAF +Q++++ L V C
Sbjct: 275 CIFKNFNLFLALIICNAIIDPLIYAFHSQELRRTLKEVLTC 315
>gi|5921992 adenosine A2a receptor [Homo sapiens]
Length = 412
Score = 92.8 bits (229), Expect = 4e-19
Identities = 78/294 (26%), Positives = 133/294 (45%), Gaps = 39/294 (13%)
Query: 50 SGTLVSCENALVVAIIVGTPAFRAPMFL----------LVGSLAVADLLAGLGLVLHFAA 99
S ++ E A+ V I+G ++L V SLA AD+ G+ L + FA
Sbjct: 6 SSVYITVELAIAVLAILGNVLVCWAVWLNSNLQNVTNYFVVSLAAADIAVGV-LAIPFAI 64
Query: 100 VFCIG--SAEMSLVLVGVLAMAFT-ASIGSLLAITVDRYLSLYNALTYYSETTVTRTYVM 156
G +A + + + T +SI SLLAI +DRY+++ L Y T TR +
Sbjct: 65 TISTGFCAACHGCLFIACFVLVLTQSSIFSLLAIAIDRYIAIRIPLRYNGLVTGTRAKGI 124
Query: 157 LALVWGGALGLGLLPVLAWN--------------CLDGLTTCGVVYPLSKNHLVVLAIAF 202
+A+ W + +GL P+L WN C +G C + N++V
Sbjct: 125 IAICWVLSFAIGLTPMLGWNNCGQPKEGKNHSQGCGEGQVACLFEDVVPMNYMVYFNFFA 184
Query: 203 FMVFGIMLQLYAQICRIVCRHAQQIALQRHLLPASHYVATRK----GIATLAVVLGAFAA 258
++ ++L L + + Q ++ LP +T + +LA+++G FA
Sbjct: 185 CVLVPLLLMLGVYLRIFLAARRQLKQMESQPLPGERARSTLQKEVHAAKSLAIIVGLFAL 244
Query: 259 CWLP------FTVYCLLGDAHSPPLYTYLTLLPATYNSMINPIIYAFRNQDVQK 306
CWLP FT +C +H+P YL ++ + NS++NP IYA+R ++ ++
Sbjct: 245 CWLPLHIINCFTFFC-PDCSHAPLWLMYLAIVLSHTNSVVNPFIYAYRIREFRQ 297
>gi|115305569 adenosine A1 receptor [Homo sapiens]
Length = 326
Score = 87.8 bits (216), Expect = 1e-17
Identities = 77/270 (28%), Positives = 122/270 (45%), Gaps = 28/270 (10%)
Query: 58 NALVVAIIVGTPAFRAPMFLLVGSLAVADLLAGLGLVLHFAAVFCIGSAEM--SLVLVGV 115
N LV+ + A R F + SLAVAD+ G LV+ A + IG + ++V
Sbjct: 27 NVLVIWAVKVNQALRDATFCFIVSLAVADVAVG-ALVIPLAILINIGPQTYFHTCLMVAC 85
Query: 116 LAMAFT-ASIGSLLAITVDRYLSLYNALTYYSETTVTRTYVMLALVWGGALGLGLLPVLA 174
+ T +SI +LLAI VDRYL + L Y T R V +A W + +GL P+
Sbjct: 86 PVLILTQSSILALLAIAVDRYLRVKIPLRYKMVVTPRRAAVAIAGCWILSFVVGLTPMFG 145
Query: 175 WNCLDGLTTC-----GVVYPLSKNHL-VVLAIAFFMVFG----------IMLQLYAQICR 218
WN L + + P+ K V+++ + + F +M+ +Y ++
Sbjct: 146 WNNLSAVERAWAANGSMGEPVIKCEFEKVISMEYMVYFNFFVWVLPPLLLMVLIYLEVFY 205
Query: 219 IVCRHAQQIALQRHLLPASHYVATRKGIATLAVVLGAFAACWLP------FTVYCLLGDA 272
++ + + P +Y K +LA++L FA WLP T++C
Sbjct: 206 LIRKQLNKKVSASSGDPQKYYGKELKIAKSLALILFLFALSWLPLHILNCITLFC--PSC 263
Query: 273 HSPPLYTYLTLLPATYNSMINPIIYAFRNQ 302
H P + TY+ + NS +NPI+YAFR Q
Sbjct: 264 HKPSILTYIAIFLTHGNSAMNPIVYAFRIQ 293
>gi|4501947 adenosine A1 receptor [Homo sapiens]
Length = 326
Score = 87.8 bits (216), Expect = 1e-17
Identities = 77/270 (28%), Positives = 122/270 (45%), Gaps = 28/270 (10%)
Query: 58 NALVVAIIVGTPAFRAPMFLLVGSLAVADLLAGLGLVLHFAAVFCIGSAEM--SLVLVGV 115
N LV+ + A R F + SLAVAD+ G LV+ A + IG + ++V
Sbjct: 27 NVLVIWAVKVNQALRDATFCFIVSLAVADVAVG-ALVIPLAILINIGPQTYFHTCLMVAC 85
Query: 116 LAMAFT-ASIGSLLAITVDRYLSLYNALTYYSETTVTRTYVMLALVWGGALGLGLLPVLA 174
+ T +SI +LLAI VDRYL + L Y T R V +A W + +GL P+
Sbjct: 86 PVLILTQSSILALLAIAVDRYLRVKIPLRYKMVVTPRRAAVAIAGCWILSFVVGLTPMFG 145
Query: 175 WNCLDGLTTC-----GVVYPLSKNHL-VVLAIAFFMVFG----------IMLQLYAQICR 218
WN L + + P+ K V+++ + + F +M+ +Y ++
Sbjct: 146 WNNLSAVERAWAANGSMGEPVIKCEFEKVISMEYMVYFNFFVWVLPPLLLMVLIYLEVFY 205
Query: 219 IVCRHAQQIALQRHLLPASHYVATRKGIATLAVVLGAFAACWLP------FTVYCLLGDA 272
++ + + P +Y K +LA++L FA WLP T++C
Sbjct: 206 LIRKQLNKKVSASSGDPQKYYGKELKIAKSLALILFLFALSWLPLHILNCITLFC--PSC 263
Query: 273 HSPPLYTYLTLLPATYNSMINPIIYAFRNQ 302
H P + TY+ + NS +NPI+YAFR Q
Sbjct: 264 HKPSILTYIAIFLTHGNSAMNPIVYAFRIQ 293
>gi|197085610 histamine receptor H2 isoform 1 [Homo sapiens]
Length = 397
Score = 85.9 bits (211), Expect = 5e-17
Identities = 86/283 (30%), Positives = 134/283 (47%), Gaps = 28/283 (9%)
Query: 53 LVSCENALVVAIIVG-TPAFRAPMFLLVGSLAVADLLAGLGLVLHFAAVFCIGSAEMSL- 110
L++ +VV + VG R + SLA+ DLL GL LVL F+A++ + S + S
Sbjct: 30 LITVAGNVVVCLAVGLNRRLRNLTNCFIVSLAITDLLLGL-LVLPFSAIYQL-SCKWSFG 87
Query: 111 -----VLVGVLAMAFTASIGSLLAITVDRYLSLYNALTYYSETTVTRTYVMLALVWGGAL 165
+ + M TASI +L I++DRY ++ + L Y T R + L L+W ++
Sbjct: 88 KVFCNIYTSLDVMLCTASILNLFMISLDRYCAVMDPLRYPVLVTPVRVAISLVLIWVISI 147
Query: 166 GLGLLPV-LAWNCLD-----GLTTCGVVYPLSKNH-LVVLAIAFFMVFGIMLQLYAQICR 218
L L + L WN + TT +++ + LV + F++ IM Y +I +
Sbjct: 148 TLSFLSIHLGWNSRNETSKGNHTTSKCKVQVNEVYGLVDGLVTFYLPLLIMCITYYRIFK 207
Query: 219 IVCRHAQQIALQRHLLPASHYVAT---RKGIATLAVVLGAFAACWLP-FTVYC---LLGD 271
+ A++I H+ +S AT K TLA V+GAF CW P FT + L GD
Sbjct: 208 VARDQAKRI---NHI--SSWKAATIREHKATVTLAAVMGAFIICWFPYFTAFVYRGLRGD 262
Query: 272 AHSPPLYTYLTLLPATYNSMINPIIYAFRNQDVQKVLWAVCCC 314
+ + L NS +NPI+YA N+D + + CC
Sbjct: 263 DAINEVLEAIVLWLGYANSALNPILYAALNRDFRTGYQQLFCC 305
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.327 0.139 0.443
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 12,421,524
Number of Sequences: 37866
Number of extensions: 555005
Number of successful extensions: 4324
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 252
Number of HSP's successfully gapped in prelim test: 391
Number of HSP's that attempted gapping in prelim test: 3385
Number of HSP's gapped (non-prelim): 845
length of query: 330
length of database: 18,247,518
effective HSP length: 103
effective length of query: 227
effective length of database: 14,347,320
effective search space: 3256841640
effective search space used: 3256841640
T: 11
A: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.7 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Home |
Table of Contents |
Search text |
Search genes |
Search sequences |
Purchase |
FAQ |
Blog |
Help
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.