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Search of human proteins with 4826671
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|4826671 cadherin 18, type 2 preproprotein [Homo sapiens]
(790 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|4826671 cadherin 18, type 2 preproprotein [Homo sapiens] 1588 0.0
gi|16306487 cadherin 7, type 2 preproprotein [Homo sapiens] 956 0.0
gi|16306489 cadherin 7, type 2 preproprotein [Homo sapiens] 956 0.0
gi|16306530 cadherin 10, type 2 preproprotein [Homo sapiens] 943 0.0
gi|16445393 cadherin 12, type 2 preproprotein [Homo sapiens] 937 0.0
gi|16306532 cadherin 11, type 2 preproprotein [Homo sapiens] 926 0.0
gi|90193626 cadherin 9, type 2 preproprotein [Homo sapiens] 921 0.0
gi|4826673 cadherin 6, type 2 preproprotein [Homo sapiens] 915 0.0
gi|16306537 cadherin 20, type 2 preproprotein [Homo sapiens] 909 0.0
gi|16306539 cadherin 8, type 2 preproprotein [Homo sapiens] 906 0.0
gi|16753221 cadherin 22 precursor [Homo sapiens] 798 0.0
gi|32880203 cadherin-like 24 isoform 2 [Homo sapiens] 774 0.0
gi|32880206 cadherin-like 24 isoform 1 [Homo sapiens] 755 0.0
gi|12656655 cadherin 19, type 2 preproprotein [Homo sapiens] 679 0.0
gi|166362713 cadherin 5, type 2 preproprotein [Homo sapiens] 536 e-152
gi|14589893 cadherin 4, type 1 preproprotein [Homo sapiens] 397 e-110
gi|14589889 cadherin 2, type 1 preproprotein [Homo sapiens] 397 e-110
gi|4757960 cadherin 1, type 1 preproprotein [Homo sapiens] 373 e-103
gi|4826669 cadherin 15 preproprotein [Homo sapiens] 364 e-100
gi|14589891 cadherin 3, type 1 preproprotein [Homo sapiens] 357 2e-98
gi|13435361 desmocollin 1 isoform Dsc1a preproprotein [Homo sapi... 274 3e-73
gi|4826702 desmocollin 1 isoform Dsc1b preproprotein [Homo sapiens] 270 3e-72
gi|148539846 desmocollin 3 isoform Dsc3a preproprotein [Homo sap... 269 9e-72
gi|148539848 desmocollin 3 isoform Dsc3b preproprotein [Homo sap... 262 8e-70
gi|13435364 desmocollin 2 isoform Dsc2a preproprotein [Homo sapi... 247 3e-65
gi|4502719 cadherin 13 preproprotein [Homo sapiens] 245 1e-64
gi|13435366 desmocollin 2 isoform Dsc2b preproprotein [Homo sapi... 244 3e-64
gi|66346693 FAT tumor suppressor 1 precursor [Homo sapiens] 232 1e-60
gi|29570800 cadherin-like 26 isoform a [Homo sapiens] 219 6e-57
gi|221316595 cadherin 17 precursor [Homo sapiens] 218 1e-56
>gi|4826671 cadherin 18, type 2 preproprotein [Homo sapiens]
Length = 790
Score = 1588 bits (4112), Expect = 0.0
Identities = 790/790 (100%), Positives = 790/790 (100%)
Query: 1 MKITSTSCICPVLVCLCFVQRCYGTAHHSSIKVMRNQTKHIEGETEVHHRPKRGWVWNQF 60
MKITSTSCICPVLVCLCFVQRCYGTAHHSSIKVMRNQTKHIEGETEVHHRPKRGWVWNQF
Sbjct: 1 MKITSTSCICPVLVCLCFVQRCYGTAHHSSIKVMRNQTKHIEGETEVHHRPKRGWVWNQF 60
Query: 61 FVLEEHMGPDPQYVGKLHSNSDKGDGSVKYILTGEGAGTIFIIDDTTGDIHSTKSLDREQ 120
FVLEEHMGPDPQYVGKLHSNSDKGDGSVKYILTGEGAGTIFIIDDTTGDIHSTKSLDREQ
Sbjct: 61 FVLEEHMGPDPQYVGKLHSNSDKGDGSVKYILTGEGAGTIFIIDDTTGDIHSTKSLDREQ 120
Query: 121 KTHYVLHAQAIDRRTNKPLEPESEFIIKVQDINDNAPKFTDGPYIVTVPEMSDMGTSVLQ 180
KTHYVLHAQAIDRRTNKPLEPESEFIIKVQDINDNAPKFTDGPYIVTVPEMSDMGTSVLQ
Sbjct: 121 KTHYVLHAQAIDRRTNKPLEPESEFIIKVQDINDNAPKFTDGPYIVTVPEMSDMGTSVLQ 180
Query: 181 VTATDADDPTYGNSARVVYSILQGQPYFSVDPKTGVIRTALHNMDREAREHYSVVIQAKD 240
VTATDADDPTYGNSARVVYSILQGQPYFSVDPKTGVIRTALHNMDREAREHYSVVIQAKD
Sbjct: 181 VTATDADDPTYGNSARVVYSILQGQPYFSVDPKTGVIRTALHNMDREAREHYSVVIQAKD 240
Query: 241 MAGQVGGLSGSTTVNITLTDVNDNPPRFPQKHYQLYVPESAQVGSAVGKIKANDADTGSN 300
MAGQVGGLSGSTTVNITLTDVNDNPPRFPQKHYQLYVPESAQVGSAVGKIKANDADTGSN
Sbjct: 241 MAGQVGGLSGSTTVNITLTDVNDNPPRFPQKHYQLYVPESAQVGSAVGKIKANDADTGSN 300
Query: 301 ADMTYSIINGDGMGIFSISTDKETREGILSLKKPLNYEKKKSYTLNIEGANTHLDFRFSH 360
ADMTYSIINGDGMGIFSISTDKETREGILSLKKPLNYEKKKSYTLNIEGANTHLDFRFSH
Sbjct: 301 ADMTYSIINGDGMGIFSISTDKETREGILSLKKPLNYEKKKSYTLNIEGANTHLDFRFSH 360
Query: 361 LGPFKDATMLKIIVGDVDEPPLFSMPSYLMEVYENAKIGTVVGTVLAQDPDSTNSLVRYF 420
LGPFKDATMLKIIVGDVDEPPLFSMPSYLMEVYENAKIGTVVGTVLAQDPDSTNSLVRYF
Sbjct: 361 LGPFKDATMLKIIVGDVDEPPLFSMPSYLMEVYENAKIGTVVGTVLAQDPDSTNSLVRYF 420
Query: 421 INYNVEDDRFFNIDANTGTIRTTKVLDREETPWYNITVTASEIDNPDLLSHVTVGIRVLD 480
INYNVEDDRFFNIDANTGTIRTTKVLDREETPWYNITVTASEIDNPDLLSHVTVGIRVLD
Sbjct: 421 INYNVEDDRFFNIDANTGTIRTTKVLDREETPWYNITVTASEIDNPDLLSHVTVGIRVLD 480
Query: 481 VNDNPPELAREYDIIVCENSKPGQVIHTISATDKDDFANGPRFNFFLDERLPVNPNFTLK 540
VNDNPPELAREYDIIVCENSKPGQVIHTISATDKDDFANGPRFNFFLDERLPVNPNFTLK
Sbjct: 481 VNDNPPELAREYDIIVCENSKPGQVIHTISATDKDDFANGPRFNFFLDERLPVNPNFTLK 540
Query: 541 DNEDNTASILTRRRRFSRTVQDVYYLPIMISDGGIPSLSSSSTLTIRVCACERDGRVRTC 600
DNEDNTASILTRRRRFSRTVQDVYYLPIMISDGGIPSLSSSSTLTIRVCACERDGRVRTC
Sbjct: 541 DNEDNTASILTRRRRFSRTVQDVYYLPIMISDGGIPSLSSSSTLTIRVCACERDGRVRTC 600
Query: 601 HAEAFLSSAGLSTGALIAILLCVLILLAIVVLFITLRRSKKEPLIISEEDVRENVVTYDD 660
HAEAFLSSAGLSTGALIAILLCVLILLAIVVLFITLRRSKKEPLIISEEDVRENVVTYDD
Sbjct: 601 HAEAFLSSAGLSTGALIAILLCVLILLAIVVLFITLRRSKKEPLIISEEDVRENVVTYDD 660
Query: 661 EGGGEEDTEAFDITALRNPSAAEELKYRRDIRPEVKLTPRHQTSSTLESIDVQEFIKQRL 720
EGGGEEDTEAFDITALRNPSAAEELKYRRDIRPEVKLTPRHQTSSTLESIDVQEFIKQRL
Sbjct: 661 EGGGEEDTEAFDITALRNPSAAEELKYRRDIRPEVKLTPRHQTSSTLESIDVQEFIKQRL 720
Query: 721 AEADLDPSVPPYDSLQTYAYEGQRSEAGSISSLDSATTQSDQDYHYLGDWGPEFKKLAEL 780
AEADLDPSVPPYDSLQTYAYEGQRSEAGSISSLDSATTQSDQDYHYLGDWGPEFKKLAEL
Sbjct: 721 AEADLDPSVPPYDSLQTYAYEGQRSEAGSISSLDSATTQSDQDYHYLGDWGPEFKKLAEL 780
Query: 781 YGEIESERTT 790
YGEIESERTT
Sbjct: 781 YGEIESERTT 790
>gi|16306487 cadherin 7, type 2 preproprotein [Homo sapiens]
Length = 785
Score = 956 bits (2471), Expect = 0.0
Identities = 473/734 (64%), Positives = 571/734 (77%), Gaps = 1/734 (0%)
Query: 50 RPKRGWVWNQFFVLEEHMGPDPQYVGKLHSNSDKGDGSVKYILTGEGAGTIFIIDDTTGD 109
R KR WVWNQFFVLEE+MG DP YVGKLHS+ DKGDGS+KYIL+GEGA +IFIID+ TGD
Sbjct: 44 RTKRSWVWNQFFVLEEYMGSDPLYVGKLHSDVDKGDGSIKYILSGEGASSIFIIDENTGD 103
Query: 110 IHSTKSLDREQKTHYVLHAQAIDRRTNKPLEPESEFIIKVQDINDNAPKFTDGPYIVTVP 169
IH+TK LDRE++ +Y L AQA+DR TNKP+EPESEF+IK+QDINDN PKF DGPY VP
Sbjct: 104 IHATKRLDREEQAYYTLRAQALDRLTNKPVEPESEFVIKIQDINDNEPKFLDGPYTAGVP 163
Query: 170 EMSDMGTSVLQVTATDADDPTYGNSARVVYSILQGQPYFSVDPKTGVIRTALHNMDREAR 229
EMS +GTSV+QVTATDADDPTYGNSARVVYSILQGQPYFSV+PKTGVI+TAL NMDREA+
Sbjct: 164 EMSPVGTSVVQVTATDADDPTYGNSARVVYSILQGQPYFSVEPKTGVIKTALPNMDREAK 223
Query: 230 EHYSVVIQAKDMAGQVGGLSGSTTVNITLTDVNDNPPRFPQKHYQLYVPESAQVGSAVGK 289
+ Y +VIQAKDM GQ GGLSG+T+V +TLTDVNDNPPRFP++ YQ VPES V S V +
Sbjct: 224 DQYLLVIQAKDMVGQNGGLSGTTSVTVTLTDVNDNPPRFPRRSYQYNVPESLPVASVVAR 283
Query: 290 IKANDADTGSNADMTYSIINGDGMGIFSISTDKETREGILSLKKPLNYEKKKSYTLNIEG 349
IKA DAD G+NA+M Y I++GDG+GIF IS DKET+EGI++++K L++E K SYTL IE
Sbjct: 284 IKAADADIGANAEMEYKIVDGDGLGIFKISVDKETQEGIITIQKELDFEAKTSYTLRIEA 343
Query: 350 ANTHLDFRFSHLGPFKDATMLKIIVGDVDEPPLFSMPSYLMEVYENAKIGTVVGTVLAQD 409
AN D RF LGPF D T +KIIV DVDEPP+FS P Y MEV E ++G ++GTV A D
Sbjct: 344 ANKDADPRFLSLGPFSDTTTVKIIVEDVDEPPVFSSPLYPMEVSEATQVGNIIGTVAAHD 403
Query: 410 PDSTNSLVRYFINYNVEDDRFFNIDANTGTIRTTKVLDREETPWYNITVTASEIDNPDLL 469
PDS+NS VRY I+ N + +R+FNIDAN+G I T K LDRE +NITV A E NP +
Sbjct: 404 PDSSNSPVRYSIDRNTDLERYFNIDANSGVITTAKSLDRETNAIHNITVLAMESQNPSQV 463
Query: 470 SHVTVGIRVLDVNDNPPELAREYDIIVCENSKPGQVIHTISATDKDDFANGPRFNFFLDE 529
V I +LD+NDN PE A +Y+ VCEN++PGQVI ISA DKD+ +NG +F F L
Sbjct: 464 GRGYVAITILDINDNAPEFAMDYETTVCENAQPGQVIQKISAVDKDEPSNGHQFYFSLTT 523
Query: 530 RLPVNPNFTLKDNEDNTASILTRRRRFSRTVQDVYYLPIMISDGGIPSLSSSSTLTIRVC 589
N NF+LKDN+DNTASILTRR F R Q VYYLPI I D G PSLSS++TLTIRVC
Sbjct: 524 DATNNHNFSLKDNKDNTASILTRRNGFRRQEQSVYYLPIFIVDSGSPSLSSTNTLTIRVC 583
Query: 590 ACERDGRVRTCHAEAFLSSAGLSTGALIAILLCVLILLAIVVLFITLRRSKKEPLIISEE 649
C+ DG +TC+AEA++ AGLSTGALIAIL CVL LL +++L +T+RR KKEPLI EE
Sbjct: 584 DCDADGVAQTCNAEAYVLPAGLSTGALIAILACVLTLLVLILLIVTMRRRKKEPLIFDEE 643
Query: 650 -DVRENVVTYDDEGGGEEDTEAFDITALRNPSAAEELKYRRDIRPEVKLTPRHQTSSTLE 708
D+REN+V YDDEGGGEEDTEAFD+ ALRN + + K RRD+ PE++ R S +
Sbjct: 644 RDIRENIVRYDDEGGGEEDTEAFDMAALRNLNVIRDTKTRRDVTPEIQFLSRPAFKSIPD 703
Query: 709 SIDVQEFIKQRLAEADLDPSVPPYDSLQTYAYEGQRSEAGSISSLDSATTQSDQDYHYLG 768
++ +EFI +RL EAD+DP PPYDSLQTYA+EG S A S+SSLDS ++ SDQ+Y YL
Sbjct: 704 NVIFREFIWERLKEADVDPGAPPYDSLQTYAFEGNGSVAESLSSLDSISSNSDQNYDYLS 763
Query: 769 DWGPEFKKLAELYG 782
DWGP FK+LA++YG
Sbjct: 764 DWGPRFKRLADMYG 777
>gi|16306489 cadherin 7, type 2 preproprotein [Homo sapiens]
Length = 785
Score = 956 bits (2471), Expect = 0.0
Identities = 473/734 (64%), Positives = 571/734 (77%), Gaps = 1/734 (0%)
Query: 50 RPKRGWVWNQFFVLEEHMGPDPQYVGKLHSNSDKGDGSVKYILTGEGAGTIFIIDDTTGD 109
R KR WVWNQFFVLEE+MG DP YVGKLHS+ DKGDGS+KYIL+GEGA +IFIID+ TGD
Sbjct: 44 RTKRSWVWNQFFVLEEYMGSDPLYVGKLHSDVDKGDGSIKYILSGEGASSIFIIDENTGD 103
Query: 110 IHSTKSLDREQKTHYVLHAQAIDRRTNKPLEPESEFIIKVQDINDNAPKFTDGPYIVTVP 169
IH+TK LDRE++ +Y L AQA+DR TNKP+EPESEF+IK+QDINDN PKF DGPY VP
Sbjct: 104 IHATKRLDREEQAYYTLRAQALDRLTNKPVEPESEFVIKIQDINDNEPKFLDGPYTAGVP 163
Query: 170 EMSDMGTSVLQVTATDADDPTYGNSARVVYSILQGQPYFSVDPKTGVIRTALHNMDREAR 229
EMS +GTSV+QVTATDADDPTYGNSARVVYSILQGQPYFSV+PKTGVI+TAL NMDREA+
Sbjct: 164 EMSPVGTSVVQVTATDADDPTYGNSARVVYSILQGQPYFSVEPKTGVIKTALPNMDREAK 223
Query: 230 EHYSVVIQAKDMAGQVGGLSGSTTVNITLTDVNDNPPRFPQKHYQLYVPESAQVGSAVGK 289
+ Y +VIQAKDM GQ GGLSG+T+V +TLTDVNDNPPRFP++ YQ VPES V S V +
Sbjct: 224 DQYLLVIQAKDMVGQNGGLSGTTSVTVTLTDVNDNPPRFPRRSYQYNVPESLPVASVVAR 283
Query: 290 IKANDADTGSNADMTYSIINGDGMGIFSISTDKETREGILSLKKPLNYEKKKSYTLNIEG 349
IKA DAD G+NA+M Y I++GDG+GIF IS DKET+EGI++++K L++E K SYTL IE
Sbjct: 284 IKAADADIGANAEMEYKIVDGDGLGIFKISVDKETQEGIITIQKELDFEAKTSYTLRIEA 343
Query: 350 ANTHLDFRFSHLGPFKDATMLKIIVGDVDEPPLFSMPSYLMEVYENAKIGTVVGTVLAQD 409
AN D RF LGPF D T +KIIV DVDEPP+FS P Y MEV E ++G ++GTV A D
Sbjct: 344 ANKDADPRFLSLGPFSDTTTVKIIVEDVDEPPVFSSPLYPMEVSEATQVGNIIGTVAAHD 403
Query: 410 PDSTNSLVRYFINYNVEDDRFFNIDANTGTIRTTKVLDREETPWYNITVTASEIDNPDLL 469
PDS+NS VRY I+ N + +R+FNIDAN+G I T K LDRE +NITV A E NP +
Sbjct: 404 PDSSNSPVRYSIDRNTDLERYFNIDANSGVITTAKSLDRETNAIHNITVLAMESQNPSQV 463
Query: 470 SHVTVGIRVLDVNDNPPELAREYDIIVCENSKPGQVIHTISATDKDDFANGPRFNFFLDE 529
V I +LD+NDN PE A +Y+ VCEN++PGQVI ISA DKD+ +NG +F F L
Sbjct: 464 GRGYVAITILDINDNAPEFAMDYETTVCENAQPGQVIQKISAVDKDEPSNGHQFYFSLTT 523
Query: 530 RLPVNPNFTLKDNEDNTASILTRRRRFSRTVQDVYYLPIMISDGGIPSLSSSSTLTIRVC 589
N NF+LKDN+DNTASILTRR F R Q VYYLPI I D G PSLSS++TLTIRVC
Sbjct: 524 DATNNHNFSLKDNKDNTASILTRRNGFRRQEQSVYYLPIFIVDSGSPSLSSTNTLTIRVC 583
Query: 590 ACERDGRVRTCHAEAFLSSAGLSTGALIAILLCVLILLAIVVLFITLRRSKKEPLIISEE 649
C+ DG +TC+AEA++ AGLSTGALIAIL CVL LL +++L +T+RR KKEPLI EE
Sbjct: 584 DCDADGVAQTCNAEAYVLPAGLSTGALIAILACVLTLLVLILLIVTMRRRKKEPLIFDEE 643
Query: 650 -DVRENVVTYDDEGGGEEDTEAFDITALRNPSAAEELKYRRDIRPEVKLTPRHQTSSTLE 708
D+REN+V YDDEGGGEEDTEAFD+ ALRN + + K RRD+ PE++ R S +
Sbjct: 644 RDIRENIVRYDDEGGGEEDTEAFDMAALRNLNVIRDTKTRRDVTPEIQFLSRPAFKSIPD 703
Query: 709 SIDVQEFIKQRLAEADLDPSVPPYDSLQTYAYEGQRSEAGSISSLDSATTQSDQDYHYLG 768
++ +EFI +RL EAD+DP PPYDSLQTYA+EG S A S+SSLDS ++ SDQ+Y YL
Sbjct: 704 NVIFREFIWERLKEADVDPGAPPYDSLQTYAFEGNGSVAESLSSLDSISSNSDQNYDYLS 763
Query: 769 DWGPEFKKLAELYG 782
DWGP FK+LA++YG
Sbjct: 764 DWGPRFKRLADMYG 777
>gi|16306530 cadherin 10, type 2 preproprotein [Homo sapiens]
Length = 788
Score = 943 bits (2437), Expect = 0.0
Identities = 461/744 (61%), Positives = 588/744 (79%), Gaps = 5/744 (0%)
Query: 46 EVHHRPKRGWVWNQFFVLEEHMGPDPQYVGKLHSNSDKGDGSVKYILTGEGAGTIFIIDD 105
++ HR KRGW+WNQFF+LEE+ G D QYVGKLHS+ DKGDGS+KYIL+G+GAGT+FIID+
Sbjct: 47 KILHRQKRGWMWNQFFLLEEYTGSDYQYVGKLHSDQDKGDGSLKYILSGDGAGTLFIIDE 106
Query: 106 TTGDIHSTKSLDREQKTHYVLHAQAIDRRTNKPLEPESEFIIKVQDINDNAPKFTDGPYI 165
TGDIH+T+ +DRE+K Y L AQAI+RRT +P+EPESEF+IK+ DINDN P F + Y
Sbjct: 107 KTGDIHATRRIDREEKAFYTLRAQAINRRTLRPVEPESEFVIKIHDINDNEPTFPEEIYT 166
Query: 166 VTVPEMSDMGTSVLQVTATDADDPTYGNSARVVYSILQGQPYFSVDPKTGVIRTALHNMD 225
+VPEMS +GTSV+QVTATDADDP+YGNSARV+YSILQGQPYFSV+P+TG+IRTAL NM+
Sbjct: 167 ASVPEMSVVGTSVVQVTATDADDPSYGNSARVIYSILQGQPYFSVEPETGIIRTALPNMN 226
Query: 226 REAREHYSVVIQAKDMAGQVGGLSGSTTVNITLTDVNDNPPRFPQKHYQLYVPESAQVGS 285
RE RE Y VVIQAKDM GQ+GGLSG+TTVNITLTDVNDNPPRFPQ L V ES+ VG+
Sbjct: 227 RENREQYQVVIQAKDMGGQMGGLSGTTTVNITLTDVNDNPPRFPQNTIHLRVLESSPVGT 286
Query: 286 AVGKIKANDADTGSNADMTYSIINGDGMGIFSISTDKETREGILSLKKPLNYEKKKSYTL 345
A+G +KA DADTG NA++ Y II+GDG +F I T+K+T+EGI+++KKPL+YE ++ YTL
Sbjct: 287 AIGSVKATDADTGKNAEVEYRIIDGDGTDMFDIVTEKDTQEGIITVKKPLDYESRRLYTL 346
Query: 346 NIEGANTHLDFRFSHLGPFKDATMLKIIVGDVDEPPLFSMPSYLMEVYENAKIGTVVGTV 405
+E NTH+D RF +LGPFKD T++KI + DVDEPP+FS SYL EV+E+ ++GT++GTV
Sbjct: 347 KVEAENTHVDPRFYYLGPFKDTTIVKISIEDVDEPPVFSRSSYLFEVHEDIEVGTIIGTV 406
Query: 406 LAQDPDSTNSLVRYFINYNVEDDRFFNIDANTGTIRTTKVLDREETPWYNITVTASEIDN 465
+A+DPDS +S +R+ ++ + + DR FNI + G++ T+K LDRE + W+N+TV A+EI+N
Sbjct: 407 MARDPDSISSPIRFSLDRHTDLDRIFNIHSGNGSLYTSKPLDRELSQWHNLTVIAAEINN 466
Query: 466 PDLLSHVTVGIRVLDVNDNPPELAREYDIIVCENSKPGQVIHTISATDKDDFANGPRFNF 525
P + V V +R+LDVNDN P+ A YD VCEN++PGQ+I TISA DKDD G +F F
Sbjct: 467 PKETTRVAVFVRILDVNDNAPQFAVFYDTFVCENARPGQLIQTISAVDKDDPLGGQKFFF 526
Query: 526 FLDERLPVNPNFTLKDNEDNTASILTRRRRFSRTVQDVYYLPIMISDGGIPSLSSSSTLT 585
L VNPNFT++DNEDNTA ILTR+ F+R Y LP++ISD P SS+ TLT
Sbjct: 527 SL---AAVNPNFTVQDNEDNTARILTRKNGFNRHEISTYLLPVVISDNDYPIQSSTGTLT 583
Query: 586 IRVCACERDGRVRTCHAEAFLSSAGLSTGALIAILLCVLILLAIVVLFITLRRS-KKEPL 644
IRVCAC+ G +++C AEA L AGLSTGALIAILLC++ILL IVVLF L+R KKEPL
Sbjct: 584 IRVCACDSQGNMQSCSAEALLLPAGLSTGALIAILLCIIILLVIVVLFAALKRQRKKEPL 643
Query: 645 IISEEDVRENVVTYDDEGGGEEDTEAFDITALRNPSAAEELKYRRDIRPEVKLTPRHQTS 704
I+S+ED+R+N+V+Y+DEGGGEEDT+AFDI LRNP+A EE K RRDI PE PR +T
Sbjct: 644 ILSKEDIRDNIVSYNDEGGGEEDTQAFDIGTLRNPAAIEEKKLRRDIIPETLFIPR-RTP 702
Query: 705 STLESIDVQEFIKQRLAEADLDPSVPPYDSLQTYAYEGQRSEAGSISSLDSATTQSDQDY 764
+ ++ DV++FI +RL E DLDP+ PPYDSL TYAYEG S A S+SSL+S TT+ DQ+Y
Sbjct: 703 TAPDNTDVRDFINERLKEHDLDPTAPPYDSLATYAYEGNDSIAESLSSLESGTTEGDQNY 762
Query: 765 HYLGDWGPEFKKLAELYGEIESER 788
YL +WGP F KLAE+YG ES++
Sbjct: 763 DYLREWGPRFNKLAEMYGGGESDK 786
>gi|16445393 cadherin 12, type 2 preproprotein [Homo sapiens]
Length = 794
Score = 937 bits (2423), Expect = 0.0
Identities = 455/753 (60%), Positives = 573/753 (76%), Gaps = 2/753 (0%)
Query: 35 RNQTKHIEGETEVHHRPKRGWVWNQFFVLEEHMGPDPQYVGKLHSNSDKGDGSVKYILTG 94
R H+ G+ R KRGWVWNQFFVLEE++G +PQYVGKLHS+ DKG+G+VKY L+G
Sbjct: 36 RENVIHLPGQRSHFQRVKRGWVWNQFFVLEEYVGSEPQYVGKLHSDLDKGEGTVKYTLSG 95
Query: 95 EGAGTIFIIDDTTGDIHSTKSLDREQKTHYVLHAQAIDRRTNKPLEPESEFIIKVQDIND 154
+GAGT+F ID+TTGDIH+ +SLDRE+K Y L AQA+D T KPLEPESEFIIKVQDIND
Sbjct: 96 DGAGTVFTIDETTGDIHAIRSLDREEKPFYTLRAQAVDIETRKPLEPESEFIIKVQDIND 155
Query: 155 NAPKFTDGPYIVTVPEMSDMGTSVLQVTATDADDPTYGNSARVVYSILQGQPYFSVDPKT 214
N PKF DGPY+ TVPEMS +G VLQV ATDADDPTYGNSARVVYSILQGQPYFS+DPKT
Sbjct: 156 NEPKFLDGPYVATVPEMSPVGAYVLQVKATDADDPTYGNSARVVYSILQGQPYFSIDPKT 215
Query: 215 GVIRTALHNMDREAREHYSVVIQAKDMAGQVGGLSGSTTVNITLTDVNDNPPRFPQKHYQ 274
GVIRTAL NMDRE +E Y V+IQAKDM GQ+GGL+G+T VNITLTDVNDNPPRFP+ +
Sbjct: 216 GVIRTALPNMDREVKEQYQVLIQAKDMGGQLGGLAGTTIVNITLTDVNDNPPRFPKSIFH 275
Query: 275 LYVPESAQVGSAVGKIKANDADTGSNADMTYSIINGDGMGIFSISTDKETREGILSLKKP 334
L VPES+ +GSA+G+I+A D D G NA++ Y+I+ GDG +F I TD++T+EG++ LKKP
Sbjct: 276 LKVPESSPIGSAIGRIRAVDPDFGQNAEIEYNIVPGDGGNLFDIVTDEDTQEGVIKLKKP 335
Query: 335 LNYEKKKSYTLNIEGANTHLDFRFSHLGPFKDATMLKIIVGDVDEPPLFSMPSYLMEVYE 394
L++E KK+YT +E +N HLD RF GPFKD +KI V DVDEPP+FS P Y MEVYE
Sbjct: 336 LDFETKKAYTFKVEASNLHLDHRFHSAGPFKDTATVKISVLDVDEPPVFSKPLYTMEVYE 395
Query: 395 NAKIGTVVGTVLAQDPDSTNSLVRYFINYNVEDDRFFNIDANTGTIRTTKVLDREETPWY 454
+ +GT++G V AQD D +S VRYFI++ + D +F ID N GTI T ++LDRE T Y
Sbjct: 396 DTPVGTIIGAVTAQDLDVGSSAVRYFIDWKSDGDSYFTIDGNEGTIATNELLDRESTAQY 455
Query: 455 NITVTASEIDNPDLLSHVTVGIRVLDVNDNPPELAREYDIIVCENSKPGQVIHTISATDK 514
N ++ AS++ NP L S V + I VLDVN+ PPE++ Y+ VCEN+KPGQ+I +SA D+
Sbjct: 456 NFSIIASKVSNPLLTSKVNILINVLDVNEFPPEISVPYETAVCENAKPGQIIQIVSAADR 515
Query: 515 DDFANGPRFNFFLDERLPVNPNFTLKDNEDNTASILTRRRRFSRTVQDVYYLPIMISDGG 574
D G +F+F L + PNFT++D +NTA I TRR +SR Q++Y+LP++I D
Sbjct: 516 DLSPAGQQFSFRLSPEAAIKPNFTVRDFRNNTAGIETRRNGYSRRQQELYFLPVVIEDSS 575
Query: 575 IPSLSSSSTLTIRVCACERDGRVRTCHAEAFLSSAGLSTGALIAILLCVLILLAIVVLFI 634
P SS++T+TIRVC C+ DG + +C+ EA GLSTGALIAILLC++ILLAIVVL++
Sbjct: 576 YPVQSSTNTMTIRVCRCDSDGTILSCNVEAIFLPVGLSTGALIAILLCIVILLAIVVLYV 635
Query: 635 TLRR-SKKEPLIISEEDVRENVVTYDDEGGGEEDTEAFDITALRNPSAAEELKYRRDIRP 693
LRR KK+ L+ S+ED+R+NV+ YDDEGGGEEDT+AFDI ALRNP EE K RRDI+P
Sbjct: 636 ALRRQKKKDTLMTSKEDIRDNVIHYDDEGGGEEDTQAFDIGALRNPKVIEENKIRRDIKP 695
Query: 694 EVKLTPRHQTSSTLESIDVQEFIKQRLAEADLDPSVPPYDSLQTYAYEGQRSEAGSISSL 753
+ PR Q ++ D+++FI QRL E D+DP+ PPYDSL TYAYEG S A S+SS+
Sbjct: 696 DSLCLPR-QRPPMEDNTDIRDFIHQRLQENDVDPTAPPYDSLATYAYEGSGSVAESLSSI 754
Query: 754 DSATTQSDQDYHYLGDWGPEFKKLAELYGEIES 786
DS TT++DQDY YL DWGP FK LA+++GE ES
Sbjct: 755 DSLTTEADQDYDYLTDWGPRFKVLADMFGEEES 787
>gi|16306532 cadherin 11, type 2 preproprotein [Homo sapiens]
Length = 796
Score = 926 bits (2393), Expect = 0.0
Identities = 467/782 (59%), Positives = 582/782 (74%), Gaps = 7/782 (0%)
Query: 8 CICPVLVCLCFVQRCYGTAHHSSIKVMRNQTKHIEG--ETEVHHRPKRGWVWNQFFVLEE 65
C+ LVCL + + A + + H E E +V R KRGWVWNQFFV+EE
Sbjct: 6 CLQAALVCLGMLCHSHAFAPERRGHLRPSFHGHHEKGKEGQVLQRSKRGWVWNQFFVIEE 65
Query: 66 HMGPDPQYVGKLHSNSDKGDGSVKYILTGEGAGTIFIIDDTTGDIHSTKSLDREQKTHYV 125
+ GPDP VG+LHS+ D GDG++KYIL+GEGAGTIF+IDD +G+IH+TK+LDRE++ Y
Sbjct: 66 YTGPDPVLVGRLHSDIDSGDGNIKYILSGEGAGTIFVIDDKSGNIHATKTLDREERAQYT 125
Query: 126 LHAQAIDRRTNKPLEPESEFIIKVQDINDNAPKFTDGPYIVTVPEMSDMGTSVLQVTATD 185
L AQA+DR TN+PLEP SEFI+KVQDINDN P+F Y VPE S++GTSV+QVTA+D
Sbjct: 126 LMAQAVDRDTNRPLEPPSEFIVKVQDINDNPPEFLHETYHANVPERSNVGTSVIQVTASD 185
Query: 186 ADDPTYGNSARVVYSILQGQPYFSVDPKTGVIRTALHNMDREAREHYSVVIQAKDMAGQV 245
ADDPTYGNSA++VYSIL+GQPYFSV+ +TG+IRTAL NMDREA+E Y VVIQAKDM G +
Sbjct: 186 ADDPTYGNSAKLVYSILEGQPYFSVEAQTGIIRTALPNMDREAKEEYHVVIQAKDMGGHM 245
Query: 246 GGLSGSTTVNITLTDVNDNPPRFPQKHYQLYVPESAQVGSAVGKIKANDADTGSNADMTY 305
GGLSG+T V ITLTDVNDNPP+FPQ YQ+ V E+A G VG++KA D D G N +TY
Sbjct: 246 GGLSGTTKVTITLTDVNDNPPKFPQSVYQMSVSEAAVPGEEVGRVKAKDPDIGENGLVTY 305
Query: 306 SIINGDGMGIFSISTDKETREGILSLKKPLNYEKKKSYTLNIEGANTHLDFRFSHLGPFK 365
+I++GDGM F I+TD ET+EG++ LKKP+++E K++Y+L +E AN H+D +F GPFK
Sbjct: 306 NIVDGDGMESFEITTDYETQEGVIKLKKPVDFETKRAYSLKVEAANVHIDPKFISNGPFK 365
Query: 366 DATMLKIIVGDVDEPPLFSMPSYLMEVYENAKIGTVVGTVLAQDPDSTNSLVRYFINYNV 425
D +KI V D DEPP+F PSY+ EV ENA GTVVG V A+DPD+ NS +RY I+ +
Sbjct: 366 DTVTVKISVEDADEPPMFLAPSYIHEVQENAAAGTVVGRVHAKDPDAANSPIRYSIDRHT 425
Query: 426 EDDRFFNIDANTGTIRTTKVLDREETPWYNITVTASEIDNPDLLSHVTVGIRVLDVNDNP 485
+ DRFF I+ G I+TTK LDREET W NITV A+EI N + V V IRVLDVNDN
Sbjct: 426 DLDRFFTINPEDGFIKTTKPLDREETAWLNITVFAAEIHNRHQEAKVPVAIRVLDVNDNA 485
Query: 486 PELAREYDIIVCEN--SKP--GQVIHTISATDKDDFANGPRFNFFLDERLPVNPNFTLKD 541
P+ A Y+ +CE+ +KP Q I TISA DKDD ANGPRF F L + NPNFT++D
Sbjct: 486 PKFAAPYEGFICESDQTKPLSNQPIVTISADDKDDTANGPRFIFSLPPEIIHNPNFTVRD 545
Query: 542 NEDNTASILTRRRRFSRTVQDVYYLPIMISDGGIPSLSSSSTLTIRVCACERDGRVRTCH 601
N DNTA + RR FSR QD+Y LPI+ISDGGIP +SS++TLTI+VC C+ +G + +C+
Sbjct: 546 NRDNTAGVYARRGGFSRQKQDLYLLPIVISDGGIPPMSSTNTLTIKVCGCDVNGALLSCN 605
Query: 602 AEAFLSSAGLSTGALIAILLCVLILLAIVVLFITLRRSKKEPLII-SEEDVRENVVTYDD 660
AEA++ +AGLSTGALIAIL C++ILL IVVLF+TLRR KKEPLI+ EEDVREN++TYDD
Sbjct: 606 AEAYILNAGLSTGALIAILACIVILLVIVVLFVTLRRQKKEPLIVFEEEDVRENIITYDD 665
Query: 661 EGGGEEDTEAFDITALRNPSAAEELKYRRDIRPEVKLTPRHQTSSTLESIDVQEFIKQRL 720
EGGGEEDTEAFDI L+NP R+DI+PE + PR S+DV +FI R+
Sbjct: 666 EGGGEEDTEAFDIATLQNPDGINGFIPRKDIKPEYQYMPRPGLRPAPNSVDVDDFINTRI 725
Query: 721 AEADLDPSVPPYDSLQTYAYEGQRSEAGSISSLDSATTQSDQDYHYLGDWGPEFKKLAEL 780
EAD DP+ PPYDS+Q Y YEG+ S AGS+SSL+SATT SD DY YL +WGP FKKLA+L
Sbjct: 726 QEADNDPTAPPYDSIQIYGYEGRGSVAGSLSSLESATTDSDLDYDYLQNWGPRFKKLADL 785
Query: 781 YG 782
YG
Sbjct: 786 YG 787
>gi|90193626 cadherin 9, type 2 preproprotein [Homo sapiens]
Length = 789
Score = 921 bits (2381), Expect = 0.0
Identities = 449/740 (60%), Positives = 569/740 (76%), Gaps = 2/740 (0%)
Query: 50 RPKRGWVWNQFFVLEEHMGPDPQYVGKLHSNSDKGDGSVKYILTGEGAGTIFIIDDTTGD 109
R KRGW+WNQFF+LEE+ G D QYVGKLH++ DKGDG++KYILTG+GAG++F+ID+ TGD
Sbjct: 50 RTKRGWMWNQFFLLEEYTGTDTQYVGKLHTDQDKGDGNLKYILTGDGAGSLFVIDENTGD 109
Query: 110 IHSTKSLDREQKTHYVLHAQAIDRRTNKPLEPESEFIIKVQDINDNAPKFTDGPYIVTVP 169
IH+ K LDRE+K+ Y+L A+AIDR+T + +EPESEFIIK+ DINDN PKFT Y +VP
Sbjct: 110 IHAAKKLDREEKSLYILRAKAIDRKTGRQVEPESEFIIKIHDINDNEPKFTKDLYTASVP 169
Query: 170 EMSDMGTSVLQVTATDADDPTYGNSARVVYSILQGQPYFSVDPKTGVIRTALHNMDREAR 229
EMS +GTSV+QVTATDADD YGNSA+VVYSILQGQPYFSVDP++G+I+TAL +M RE R
Sbjct: 170 EMSGVGTSVIQVTATDADDANYGNSAKVVYSILQGQPYFSVDPESGIIKTALPDMSRENR 229
Query: 230 EHYSVVIQAKDMAGQVGGLSGSTTVNITLTDVNDNPPRFPQKHYQLYVPESAQVGSAVGK 289
E Y VVIQAKDM GQ+GGLSG+TTVNITLTDVN+NPPRFPQ YQ PES +G+ +G+
Sbjct: 230 EQYQVVIQAKDMGGQMGGLSGTTTVNITLTDVNNNPPRFPQSTYQFNSPESVPLGTHLGR 289
Query: 290 IKANDADTGSNADMTYSIINGDGMGIFSISTDKETREGILSLKKPLNYEKKKSYTLNIEG 349
IKAND D G NA+M YSI GDG +F + TDK+T+EGI+++K+ L++E + YTL ++
Sbjct: 290 IKANDPDVGENAEMEYSIAEGDGADMFDVITDKDTQEGIITVKQNLDFENQMLYTLRVDA 349
Query: 350 ANTHLDFRFSHLGPFKDATMLKIIVGDVDEPPLFSMPSYLMEVYENAKIGTVVGTVLAQD 409
+NTH D RF HLGPFKD ++KI V D+DEPP+F+ SYL+EV E+ K G+++G V A D
Sbjct: 350 SNTHPDPRFLHLGPFKDTAVVKISVEDIDEPPVFTKVSYLIEVDEDVKEGSIIGQVTAYD 409
Query: 410 PDSTNSLVRYFINYNVEDDRFFNIDANTGTIRTTKVLDREETPWYNITVTASEIDNPDLL 469
PD+ N+L++Y ++ + + DR F I + G+I T K LDRE +PW+NITVTA+EI+NP
Sbjct: 410 PDARNNLIKYSVDRHTDMDRIFGIHSENGSIFTLKALDRESSPWHNITVTATEINNPKQS 469
Query: 470 SHVTVGIRVLDVNDNPPELAREYDIIVCENSKPGQVIHTISATDKDDFANGPRFNFFLDE 529
SH+ V IR+LD+ND+ PE A Y+ VCEN+KPGQ+I T+S DKDD G +F F
Sbjct: 470 SHIPVFIRILDINDHAPEFAMYYETFVCENAKPGQLIQTVSVMDKDDPPRGHKFFFEPVP 529
Query: 530 RLPVNPNFTLKDNEDNTASILTRRRRFSRTVQDVYYLPIMISDGGIPSLSSSSTLTIRVC 589
+NPNFT+ DN+DNTA I+TR+ +SR Y LPI+I D P SS+ TLTIRVC
Sbjct: 530 EFTLNPNFTIVDNKDNTAGIMTRKDGYSRNKMSTYLLPILIFDNDYPIQSSTGTLTIRVC 589
Query: 590 ACERDGRVRTCHAEAFLSSAGLSTGALIAILLCVLILLAIVVLFITLRRS-KKEPLIISE 648
AC+ G +++C AEA + SAGLSTGAL+AILLCVLILL +VVLF L+R KKEPLIIS+
Sbjct: 590 ACDNQGNMQSCTAEALILSAGLSTGALVAILLCVLILLILVVLFAALKRQRKKEPLIISK 649
Query: 649 EDVRENVVTYDDEGGGEEDTEAFDITALRNPSAAEELKYRRDIRPEVKLTPRHQTSSTLE 708
+DVR+N+VTY+DEGGGEEDT+AFDI LRNP A E+ K RRD+ PE R +T E
Sbjct: 650 DDVRDNIVTYNDEGGGEEDTQAFDIGTLRNPEAREDSKLRRDVMPETIFQIR-RTVPLWE 708
Query: 709 SIDVQEFIKQRLAEADLDPSVPPYDSLQTYAYEGQRSEAGSISSLDSATTQSDQDYHYLG 768
+IDVQ+FI +RL E D DPS PPYDSL TYAYEG S A S+SSL+S T +QDY YL
Sbjct: 709 NIDVQDFIHRRLKENDADPSAPPYDSLATYAYEGNDSIADSLSSLESLTADCNQDYDYLS 768
Query: 769 DWGPEFKKLAELYGEIESER 788
DWGP FKKLA++YG +S+R
Sbjct: 769 DWGPRFKKLADMYGGDDSDR 788
>gi|4826673 cadherin 6, type 2 preproprotein [Homo sapiens]
Length = 790
Score = 915 bits (2364), Expect = 0.0
Identities = 443/741 (59%), Positives = 576/741 (77%), Gaps = 2/741 (0%)
Query: 49 HRPKRGWVWNQFFVLEEHMGPDPQYVGKLHSNSDKGDGSVKYILTGEGAGTIFIIDDTTG 108
+R KR W+WNQFF+LEE+ G D QYVGKLHS+ D+GDGS+KYIL+G+GAG +FII++ TG
Sbjct: 49 NRSKRSWMWNQFFLLEEYTGSDYQYVGKLHSDQDRGDGSLKYILSGDGAGDLFIINENTG 108
Query: 109 DIHSTKSLDREQKTHYVLHAQAIDRRTNKPLEPESEFIIKVQDINDNAPKFTDGPYIVTV 168
DI +TK LDRE+K Y+L AQAI+RRT +P+EPESEFIIK+ DINDN P FT Y TV
Sbjct: 109 DIQATKRLDREEKPVYILRAQAINRRTGRPVEPESEFIIKIHDINDNEPIFTKEVYTATV 168
Query: 169 PEMSDMGTSVLQVTATDADDPTYGNSARVVYSILQGQPYFSVDPKTGVIRTALHNMDREA 228
PEMSD+GT V+QVTATDADDPTYGNSA+VVYSILQGQPYFSV+ +TG+I+TAL NMDRE
Sbjct: 169 PEMSDVGTFVVQVTATDADDPTYGNSAKVVYSILQGQPYFSVESETGIIKTALLNMDREN 228
Query: 229 REHYSVVIQAKDMAGQVGGLSGSTTVNITLTDVNDNPPRFPQKHYQLYVPESAQVGSAVG 288
RE Y VVIQAKDM GQ+GGLSG+TTVNITLTDVNDNPPRFPQ YQ PES+ G+ +G
Sbjct: 229 REQYQVVIQAKDMGGQMGGLSGTTTVNITLTDVNDNPPRFPQSTYQFKTPESSPPGTPIG 288
Query: 289 KIKANDADTGSNADMTYSIINGDGMGIFSISTDKETREGILSLKKPLNYEKKKSYTLNIE 348
+IKA+DAD G NA++ YSI +G+G+ +F + TD+ET+EGI+++KK L++EKKK YTL +E
Sbjct: 289 RIKASDADVGENAEIEYSITDGEGLDMFDVITDQETQEGIITVKKLLDFEKKKVYTLKVE 348
Query: 349 GANTHLDFRFSHLGPFKDATMLKIIVGDVDEPPLFSMPSYLMEVYENAKIGTVVGTVLAQ 408
+N +++ RF +LGPFKD+ ++I+V DVDEPP+FS +Y++++ E+A+I T +G+V AQ
Sbjct: 349 ASNPYVEPRFLYLGPFKDSATVRIVVEDVDEPPVFSKLAYILQIREDAQINTTIGSVTAQ 408
Query: 409 DPDSTNSLVRYFINYNVEDDRFFNIDANTGTIRTTKVLDREETPWYNITVTASEIDNPDL 468
DPD+ + V+Y ++ + + DR FNID+ G+I T+K+LDRE W+NITV A+EI+NP
Sbjct: 409 DPDAARNPVKYSVDRHTDMDRIFNIDSGNGSIFTSKLLDRETLLWHNITVIATEINNPKQ 468
Query: 469 LSHVTVGIRVLDVNDNPPELAREYDIIVCENSKPGQVIHTISATDKDDFANGPRFNFFLD 528
S V + I+VLDVNDN PE A Y+ VCE +K Q+I T+ A DKDD +G +F+F L
Sbjct: 469 SSRVPLYIKVLDVNDNAPEFAEFYETFVCEKAKADQLIQTLHAVDKDDPYSGHQFSFSLA 528
Query: 529 ERLPVNPNFTLKDNEDNTASILTRRRRFSRTVQDVYYLPIMISDGGIPSLSSSSTLTIRV 588
NFT++DN+DNTA ILTR+ ++R Y LP++ISD P SS+ T+T+RV
Sbjct: 529 PEAASGSNFTIQDNKDNTAGILTRKNGYNRHEMSTYLLPVVISDNDYPVQSSTGTVTVRV 588
Query: 589 CACERDGRVRTCHAEAFLSSAGLSTGALIAILLCVLILLAIVVLFITLRRS-KKEPLIIS 647
CAC+ G +++CHAEA + GLSTGAL+AILLC++ILL VVLF LRR KKEPLIIS
Sbjct: 589 CACDHHGNMQSCHAEALIHPTGLSTGALVAILLCIVILLVTVVLFAALRRQRKKEPLIIS 648
Query: 648 EEDVRENVVTYDDEGGGEEDTEAFDITALRNPSAAEELKYRRDIRPEVKLTPRHQTSSTL 707
+ED+R+N+V+Y+DEGGGEEDT+AFDI LRNP A E+ K RRDI PE PR +T +
Sbjct: 649 KEDIRDNIVSYNDEGGGEEDTQAFDIGTLRNPEAIEDNKLRRDIVPEALFLPR-RTPTAR 707
Query: 708 ESIDVQEFIKQRLAEADLDPSVPPYDSLQTYAYEGQRSEAGSISSLDSATTQSDQDYHYL 767
++ DV++FI QRL E D DP+ PPYDSL TYAYEG S A S+SSL+S TT +DQDY YL
Sbjct: 708 DNTDVRDFINQRLKENDTDPTAPPYDSLATYAYEGTGSVADSLSSLESVTTDADQDYDYL 767
Query: 768 GDWGPEFKKLAELYGEIESER 788
DWGP FKKLA++YG ++S++
Sbjct: 768 SDWGPRFKKLADMYGGVDSDK 788
>gi|16306537 cadherin 20, type 2 preproprotein [Homo sapiens]
Length = 801
Score = 909 bits (2348), Expect = 0.0
Identities = 443/749 (59%), Positives = 562/749 (75%), Gaps = 4/749 (0%)
Query: 41 IEGETEVHHRPKRGWVWNQFFVLEEHMGPDPQYVGKLHSNSDKGDGSVKYILTGEGAGTI 100
+ + + H R KR WVWNQFFVLEE+ G DP YVGKLHS+ D+GDGS+KYIL+GEGAG +
Sbjct: 47 LSDKPQSHQRTKRSWVWNQFFVLEEYTGTDPLYVGKLHSDMDRGDGSIKYILSGEGAGIV 106
Query: 101 FIIDDTTGDIHSTKSLDREQKTHYVLHAQAIDRRTNKPLEPESEFIIKVQDINDNAPKFT 160
F IDDTTGDIH+ + LDRE++ Y L AQA+DRRT +P+EPESEFIIK+QDINDN PKF
Sbjct: 107 FTIDDTTGDIHAIQRLDREERAQYTLRAQALDRRTGRPMEPESEFIIKIQDINDNEPKFL 166
Query: 161 DGPYIVTVPEMSDMGTSVLQVTATDADDPTYGNSARVVYSILQGQPYFSVDPKTGVIRTA 220
DGPY+ TVPEMS +GTSV+QVTATDADDPTYGNSARVVYSILQGQPYFSVD KTGVIRTA
Sbjct: 167 DGPYVATVPEMSPVGTSVIQVTATDADDPTYGNSARVVYSILQGQPYFSVDSKTGVIRTA 226
Query: 221 LHNMDREAREHYSVVIQAKDMAGQVGGLSGSTTVNITLTDVNDNPPRFPQKHYQLYVPES 280
L NMDREA+E+Y V+IQAKDM GQ+GGL+G+TTVNITL+DVNDNPPRFPQKHYQ+ V ES
Sbjct: 227 LMNMDREAKEYYEVIIQAKDMGGQLGGLAGTTTVNITLSDVNDNPPRFPQKHYQMSVLES 286
Query: 281 AQVGSAVGKIKANDADTGSNADMTYSIINGDGMGIFSISTDKETREGILSLKKPLNYEKK 340
A + S VG++ A D D G NA+M Y+I++GDG F ISTD + GI+++KKPL++E K
Sbjct: 287 APISSTVGRVFAKDLDEGINAEMKYTIVDGDGADAFDISTDPNFQVGIITVKKPLSFESK 346
Query: 341 KSYTLNIEGANTHLDFRFSHLGPFKDATMLKIIVGDVDEPPLFSMPSYLMEVYENAKIGT 400
KSYTL +EGAN HL+ RF +LGPF+D T + I V DVDEPP+F Y +EV E+ IGT
Sbjct: 347 KSYTLKVEGANPHLEMRFLNLGPFQDTTTVHISVEDVDEPPVFEPGFYFVEVPEDVAIGT 406
Query: 401 VVGTVLAQDPDSTNSLVRYFINYNVEDDRFFNIDANTGTIRTTKVLDREETPWYNITVTA 460
+ + A+DPD TN+ +RY I+ + + RFF +D TG + T + LDREE W+NITV A
Sbjct: 407 TIQIISAKDPDVTNNSIRYSIDRSSDPGRFFYVDITTGALMTARPLDREEFSWHNITVLA 466
Query: 461 SEIDNPDLLSHVTVGIRVLDVNDNPPELAREYDIIVCENSKPGQVIHTISATDKDDFANG 520
E++NP + V V I+VLDVNDN PE R Y+ VCEN+K GQ+I T+SA D+DD NG
Sbjct: 467 MEMNNPSQVGSVPVTIKVLDVNDNAPEFPRFYEAFVCENAKAGQLIQTVSAVDQDDPRNG 526
Query: 521 PRFNFFLDERLPVNPNFTLKDNEDNTASILTRRRRFSRTVQDVYYLPIMISDGGIPSLSS 580
F + L NPNFT++DN+DNTA ILTRR F + Q V++LPI+I+D G P LSS
Sbjct: 527 QHFYYSLAPEAANNPNFTIRDNQDNTARILTRRSGFRQQEQSVFHLPILIADSGQPVLSS 586
Query: 581 SSTLTIRVCACERDGRVRTCHAEAFLSSAGLSTGALIAILLCVLILLAIVVLFITLRRSK 640
+ TLTI+VC+C+ DG V +C EA++ LS GALIAIL C+ +LL +V+L +++RR +
Sbjct: 587 TGTLTIQVCSCDDDGHVMSCSPEAYMLPVSLSRGALIAILACIFVLLVLVLLILSMRRHR 646
Query: 641 KEPLII-SEEDVRENVVTYDDEGGGEEDTEAFDITALRNPSAAE---ELKYRRDIRPEVK 696
K+P II EE++ EN+V YDDEGGGEEDTEAFDI A+ NP A+ K R+D+ PE++
Sbjct: 647 KQPYIIDDEENIHENIVRYDDEGGGEEDTEAFDIAAMWNPREAQAGAAPKTRQDMLPEIE 706
Query: 697 LTPRHQTSSTLESIDVQEFIKQRLAEADLDPSVPPYDSLQTYAYEGQRSEAGSISSLDSA 756
R+ + + V ++ +L EAD+D PP+DSLQTY +EG S AGS+SSL SA
Sbjct: 707 SLSRYVPQTCAVNSTVHSYVLAKLYEADMDLWAPPFDSLQTYMFEGDGSVAGSLSSLQSA 766
Query: 757 TTQSDQDYHYLGDWGPEFKKLAELYGEIE 785
T+ S+Q + +L DWGP F+KLAELYG E
Sbjct: 767 TSDSEQSFDFLTDWGPRFRKLAELYGASE 795
>gi|16306539 cadherin 8, type 2 preproprotein [Homo sapiens]
Length = 799
Score = 906 bits (2341), Expect = 0.0
Identities = 442/748 (59%), Positives = 559/748 (74%), Gaps = 1/748 (0%)
Query: 44 ETEVHHRPKRGWVWNQFFVLEEHMGPDPQYVGKLHSNSDKGDGSVKYILTGEGAGTIFII 103
E + +R KRGWVWNQ FVLEE GP+P VG+LH++ D G +KYIL+G+GAGTIF I
Sbjct: 52 EQRILNRSKRGWVWNQMFVLEEFSGPEPILVGRLHTDLDPGSKKIKYILSGDGAGTIFQI 111
Query: 104 DDTTGDIHSTKSLDREQKTHYVLHAQAIDRRTNKPLEPESEFIIKVQDINDNAPKFTDGP 163
+D TGDIH+ K LDRE+K Y L AQA+D T+KPLEP SEFIIKVQDINDNAP+F +GP
Sbjct: 112 NDVTGDIHAIKRLDREEKAEYTLTAQAVDWETSKPLEPPSEFIIKVQDINDNAPEFLNGP 171
Query: 164 YIVTVPEMSDMGTSVLQVTATDADDPTYGNSARVVYSILQGQPYFSVDPKTGVIRTALHN 223
Y TVPEMS +GTSV VTATDADDP YGNSA++VYSIL+GQPYFS++P+T +I+TAL N
Sbjct: 172 YHATVPEMSILGTSVTNVTATDADDPVYGNSAKLVYSILEGQPYFSIEPETAIIKTALPN 231
Query: 224 MDREAREHYSVVIQAKDMAGQVGGLSGSTTVNITLTDVNDNPPRFPQKHYQLYVPESAQV 283
MDREA+E Y VVIQAKDM G GGLSG+TT+ +TLTDVNDNPP+F Q Y VPE +
Sbjct: 232 MDREAKEEYLVVIQAKDMGGHSGGLSGTTTLTVTLTDVNDNPPKFAQSLYHFSVPEDVVL 291
Query: 284 GSAVGKIKANDADTGSNADMTYSIINGDGMGIFSISTDKETREGILSLKKPLNYEKKKSY 343
G+A+G++KAND D G NA +Y II+GDG +F I++D + ++GI+ L+KPL++E KKSY
Sbjct: 292 GTAIGRVKANDQDIGENAQSSYDIIDGDGTALFEITSDAQAQDGIIRLRKPLDFETKKSY 351
Query: 344 TLNIEGANTHLDFRFSHLGPFKDATMLKIIVGDVDEPPLFSMPSYLMEVYENAKIGTVVG 403
TL +E AN H+D RFS GPFKD +KI+V D DEPP+FS P+YL+EV+ENA + +V+G
Sbjct: 352 TLKVEAANVHIDPRFSGRGPFKDTATVKIVVEDADEPPVFSSPTYLLEVHENAALNSVIG 411
Query: 404 TVLAQDPDSTNSLVRYFINYNVEDDRFFNIDANTGTIRTTKVLDREETPWYNITVTASEI 463
V A+DPD T+S +R+ I+ + + +R FNI+A+ G I LDRE + W+NIT+ A+EI
Sbjct: 412 QVTARDPDITSSPIRFSIDRHTDLERQFNINADDGKITLATPLDRELSVWHNITIIATEI 471
Query: 464 DNPDLLSHVTVGIRVLDVNDNPPELAREYDIIVCENSKPGQVIHTISATDKDDFANGPRF 523
N +S V V I+VLDVNDN PE A EY+ +CEN KPGQVI T+SA DKDD NG F
Sbjct: 472 RNHSQISRVPVAIKVLDVNDNAPEFASEYEAFLCENGKPGQVIQTVSAMDKDDPKNGHYF 531
Query: 524 NFFLDERLPVNPNFTLKDNEDNTASILTRRRRFSRTVQDVYYLPIMISDGGIPSLSSSST 583
+ L + NPNFT+K NEDN+ SIL + F+R Q+VY LPI+ISD G P LSS+ST
Sbjct: 532 LYSLLPEMVNNPNFTIKKNEDNSLSILAKHNGFNRQKQEVYLLPIIISDSGNPPLSSTST 591
Query: 584 LTIRVCACERDGRVRTCHAEAFLSSAGLSTGALIAILLCVLILLAIVVLFITLRRSKKEP 643
LTIRVC C DG V++C+ EA++ GLS GALIAIL C+++LL IVVLF+TLRR K EP
Sbjct: 592 LTIRVCGCSNDGVVQSCNVEAYVLPIGLSMGALIAILACIILLLVIVVLFVTLRRHKNEP 651
Query: 644 LII-SEEDVRENVVTYDDEGGGEEDTEAFDITALRNPSAAEELKYRRDIRPEVKLTPRHQ 702
LII +EDVREN++ YDDEGGGEEDTEAFDI L+NP R+DI+P+++ PR
Sbjct: 652 LIIKDDEDVRENIIRYDDEGGGEEDTEAFDIATLQNPDGINGFLPRKDIKPDLQFMPRQG 711
Query: 703 TSSTLESIDVQEFIKQRLAEADLDPSVPPYDSLQTYAYEGQRSEAGSISSLDSATTQSDQ 762
+ +DV EFI RL EAD DP+ PPYDS+Q Y YEG+ S AGS+SSL+S T+ SDQ
Sbjct: 712 LAPVPNGVDVDEFINVRLHEADNDPTAPPYDSIQIYGYEGRGSVAGSLSSLESTTSDSDQ 771
Query: 763 DYHYLGDWGPEFKKLAELYGEIESERTT 790
++ YL DWGP FK+L ELY ES++ T
Sbjct: 772 NFDYLSDWGPRFKRLGELYSVGESDKET 799
>gi|16753221 cadherin 22 precursor [Homo sapiens]
Length = 828
Score = 798 bits (2061), Expect = 0.0
Identities = 405/758 (53%), Positives = 544/758 (71%), Gaps = 26/758 (3%)
Query: 50 RPKRGWVWNQFFVLEEHMGPDPQYVGKLHSNSDKGDGSVKYILTGEGAGTIFIIDDTTGD 109
R KRGWVWNQFFV+EE+ G +P YVGK+HS+SD+GDG++KY ++GEGAGTIF+ID+ TGD
Sbjct: 59 RVKRGWVWNQFFVVEEYTGTEPLYVGKIHSDSDEGDGAIKYTISGEGAGTIFLIDELTGD 118
Query: 110 IHSTKSLDREQKTHYVLHAQAIDRRTNKPLEPESEFIIKVQDINDNAPKFTDGPYIVTVP 169
IH+ + LDREQKT Y L AQA DR TN+ LEPESEFIIKVQDIND+ P+F GPYI +V
Sbjct: 119 IHAMERLDREQKTFYTLRAQARDRATNRLLEPESEFIIKVQDINDSEPRFLHGPYIGSVA 178
Query: 170 EMSDMGTSVLQVTATDADDPTYGNSARVVYSILQGQPYFSVDPKTGVIRTALHNMDREAR 229
E+S GTSV+QV A+DADDPTYG+SAR+VYS+L G+ +F+VDPKTGVIRTA+ ++DRE++
Sbjct: 179 ELSPTGTSVMQVMASDADDPTYGSSARLVYSVLDGEHHFTVDPKTGVIRTAVPDLDRESQ 238
Query: 230 EHYSVVIQAKDMAGQVGGLSGSTTVNITLTDVNDNPPRFPQKHYQLYVPESAQVGSAVGK 289
E Y VVIQA DMAGQ+GGLSGSTTV I +TDVNDNPPRFPQK YQ + ESA +G+AVG+
Sbjct: 239 ERYEVVIQATDMAGQLGGLSGSTTVTIVVTDVNDNPPRFPQKMYQFSIQESAPIGTAVGR 298
Query: 290 IKANDADTGSNADMTYSIINGDGMG--IFSISTDKETREGILSLKKPLNYEKKKSYTLNI 347
+KA D+D G N DMTY + + G +F ++TD +T+E I+ ++K L++E + +T+ +
Sbjct: 299 VKAEDSDVGENTDMTYHLKDESSSGGDVFKVTTDSDTQEAIIVVQKRLDFESQPVHTVIL 358
Query: 348 EGANTHLDFRFSHLGPFKDATMLKIIVGDVDEPPLFSMPSYLMEVYENAKIGTVVGTVLA 407
E N +D RF+ LG F+D ++++ V DVDEPP F PS L+EV E+A++G++VG V A
Sbjct: 359 EALNKFVDPRFADLGTFRDQAIVRVAVTDVDEPPEFRPPSGLLEVQEDAQVGSLVGVVTA 418
Query: 408 QDPDSTNSLVRYFINYNVEDDRFFNIDANTGTIRTTKVLDREETPWYNITVTASEIDNPD 467
+DPD+ N VRY I+ + D+ F+IDA+TG I T K LDRE W+NITV A E DN
Sbjct: 419 RDPDAANRPVRYAIDRESDLDQIFDIDADTGAIVTGKGLDRETAGWHNITVLAMEADNHA 478
Query: 468 LLSHVTVGIRVLDVNDNPPELAREYDIIVCENSKPGQVIHTISATDKDDFANGPRFNFFL 527
LS ++ IR+LDVNDNPPELA Y+ VCE++KPGQ+I TIS D+D+ G RF F L
Sbjct: 479 QLSRASLRIRILDVNDNPPELATPYEAAVCEDAKPGQLIQTISVVDRDEPQGGHRFYFRL 538
Query: 528 DERLPVNPNFTLKDNEDNTASILTRRRRFSRTVQDVYYLPIMISDGGIPSLSSSSTLTIR 587
P NP+F+L D +DNTA++ T+ F+R QDV++LPI++ D G P+LSS+ TLTIR
Sbjct: 539 VPEAPSNPHFSLLDIQDNTAAVHTQHVGFNRQEQDVFFLPILVVDSGPPTLSSTGTLTIR 598
Query: 588 VCACERDGRVRTCHAEAFLSSAGLSTGALIAILLCVLILLAIVVLFITLRRSKKEPLIIS 647
+C C+ G +++C+ AF+ +A LS GALIA+L+CVLIL+ +V+L +TLRR K L
Sbjct: 599 ICGCDSSGTIQSCNTTAFVMAASLSPGALIALLVCVLILVVLVLLILTLRRHHKSHLSSD 658
Query: 648 E-EDVRENVVTYDDEGGGEEDTEAFDITALRNPSAAEELK-------------------- 686
E ED+R+NV+ Y+DEGGGE+DTEA+D++ALR+ ELK
Sbjct: 659 EDEDMRDNVIKYNDEGGGEQDTEAYDMSALRSLYDFGELKGGDGGGSAGGGAGGGSGGGA 718
Query: 687 ---YRRDIRPEVKLTPRHQTSSTLESIDVQEFIKQRLAEADLDPSVPPYDSLQTYAYEGQ 743
+ + E P+ S + ++FI +++A AD D SVPPYD+ QTYA+EG
Sbjct: 719 GSPPQAHLPSERHSLPQGPPSPEPDFSVFRDFISRKVALADGDLSVPPYDAFQTYAFEGA 778
Query: 744 RSEAGSISSLDSATTQSDQDYHYLGDWGPEFKKLAELY 781
S A S+SSL S ++ S+QD+ YL WGP F+ LA LY
Sbjct: 779 DSPAASLSSLHSGSSGSEQDFAYLSSWGPRFRPLAALY 816
>gi|32880203 cadherin-like 24 isoform 2 [Homo sapiens]
Length = 781
Score = 774 bits (1999), Expect = 0.0
Identities = 398/745 (53%), Positives = 523/745 (70%), Gaps = 17/745 (2%)
Query: 50 RPKRGWVWNQFFVLEEHMGPDPQYVGKLHSNSDKGDGSVKYILTGEGAGTIFIIDDTTGD 109
R +R WVWNQFFV+EE+ GP+P +GKLHS+ D+G+G KY+LTGEGAGT+F+ID+ TG+
Sbjct: 41 RTRRSWVWNQFFVIEEYAGPEPVLIGKLHSDVDRGEGRTKYLLTGEGAGTVFVIDEATGN 100
Query: 110 IHSTKSLDREQKTHYVLHAQAIDRRTNKPLEPESEFIIKVQDINDNAPKFTDGPYIVTVP 169
IH TKSLDRE+K YVL AQA+DR +N+PLEP SEFIIKVQDINDN P F GPY TVP
Sbjct: 101 IHVTKSLDREEKAQYVLLAQAVDRASNRPLEPPSEFIIKVQDINDNPPIFPLGPYHATVP 160
Query: 170 EMSDMGTSVLQVTATDADDPTYGNSARVVYSILQGQPYFSVDPKTGVIRTALHNMDREAR 229
EMS++GTSV+QVTA DADDP+YGNSA++VY++L G P+FSVDP+TGV+RTA+ NMDRE +
Sbjct: 161 EMSNVGTSVIQVTAHDADDPSYGNSAKLVYTVLDGLPFFSVDPQTGVVRTAIPNMDRETQ 220
Query: 230 EHYSVVIQAKDMAGQVGGLSGSTTVNITLTDVNDNPPRFPQKHYQLYVPESAQVGSAVGK 289
E + VVIQAKDM G +GGLSGSTTV +TL+DVNDNPP+FPQ YQ V E+A G+ VG+
Sbjct: 221 EEFLVVIQAKDMGGHMGGLSGSTTVTVTLSDVNDNPPKFPQSLYQFSVVETAGPGTLVGR 280
Query: 290 IKANDADTGSNADMTYSIINGDGMGIFSISTDKETREGILSLKKPLNYEKKKSYTLNIEG 349
++A D D G NA M YSI++G+G FSISTD + R+G+L+++KPL++E ++SY+ +E
Sbjct: 281 LRAQDPDLGDNALMAYSILDGEGSEAFSISTDLQGRDGLLTVRKPLDFESQRSYSFRVEA 340
Query: 350 ANTHLDFRFSHLGPFKDATMLKIIVGDVDEPPLFSMPSYLMEVYENAKIGTVVGTVLAQD 409
NT +D + GPFKD +++ V D EPP F+ +Y + V EN GT+VG + A D
Sbjct: 341 TNTLIDPAYLRRGPFKDVASVRVAVQDAPEPPAFTQAAYHLTVPENKAPGTLVGQISAAD 400
Query: 410 PDSTNSLVRYFINYNVEDDRFFNIDANTGTIRTTKVLDREETPWYNITVTASEIDNPDLL 469
DS S +RY I + + +R F+I GTI T LDRE W+N+TV A+E+D+
Sbjct: 401 LDSPASPIRYSILPHSDPERCFSIQPEEGTIHTAAPLDREARAWHNLTVLATELDSSAQA 460
Query: 470 SHVTVGIRVLDVNDNPPELAREYDIIVCENSKPGQVIHTISATDKDDFANGPRFNFFLDE 529
S V V I+ LD NDN P+LA YD VC+++ PGQ+I I A D+D+ N +F
Sbjct: 461 SRVQVAIQTLDENDNAPQLAEPYDTFVCDSAAPGQLIQVIRALDRDEVGNSSHVSF---- 516
Query: 530 RLPVNP--NFTLKDNEDNTASILTRRRRFSRTVQDVYYLPIMISDGGIPSLSSSSTLTIR 587
+ P+ P NFT++DN D +AS+L R + Y +PI + D G P+LSS++T+T+
Sbjct: 517 QGPLGPDANFTVQDNRDGSASLLLPSRP-APPRHAPYLVPIELWDWGQPALSSTATVTVS 575
Query: 588 VCACERDGRVRTCHAEAFLSSAGLSTGALIAILLCVLILLAIVVLFITLRRSKKEPL-II 646
VC C+ DG V +C EA LS+AGLSTGAL+AI+ CV LLA+VVLF+ LRR K+E L ++
Sbjct: 576 VCRCQPDGSVASCWPEAHLSAAGLSTGALLAIITCVGALLALVVLFVALRRQKQEALMVL 635
Query: 647 SEEDVRENVVTYDDEGGGEEDTEAFDITALRNPSAAEE----LKYRRDIRPEVKLTPRHQ 702
EEDVREN++TYDDEGGGEEDTEAFDITAL+NP A RRD+ P +++ + +
Sbjct: 636 EEEDVRENIITYDDEGGGEEDTEAFDITALQNPDGAAPPAPGPPARRDVLPRARVSRQPR 695
Query: 703 TSSTLESIDVQEFIKQRLAEADLDPSVPPYDSLQTYAYEGQRSEAGSISSLDSATTQ--S 760
DV + + RL EAD DP VPPYDS+Q Y YEG+ S GS+SSL S + +
Sbjct: 696 PPG---PADVAQLLALRLREADEDPGVPPYDSVQVYGYEGRGSSCGSLSSLGSGSEAGGA 752
Query: 761 DQDYHYLGDWGPEFKKLAELYGEIE 785
L DWGP F+ LAELYG E
Sbjct: 753 PGPAEPLDDWGPLFRTLAELYGAKE 777
>gi|32880206 cadherin-like 24 isoform 1 [Homo sapiens]
Length = 819
Score = 755 bits (1950), Expect = 0.0
Identities = 398/783 (50%), Positives = 523/783 (66%), Gaps = 55/783 (7%)
Query: 50 RPKRGWVWNQFFVLEEHMGPDPQYVGKLHSNSDKGDGSVKYILTGEGAGTIFIIDDTTGD 109
R +R WVWNQFFV+EE+ GP+P +GKLHS+ D+G+G KY+LTGEGAGT+F+ID+ TG+
Sbjct: 41 RTRRSWVWNQFFVIEEYAGPEPVLIGKLHSDVDRGEGRTKYLLTGEGAGTVFVIDEATGN 100
Query: 110 IHSTKSLDREQKTHYVLHAQAIDRRTNKPLEPESEFIIKVQDINDNAPKFTDGPYIVTVP 169
IH TKSLDRE+K YVL AQA+DR +N+PLEP SEFIIKVQDINDN P F GPY TVP
Sbjct: 101 IHVTKSLDREEKAQYVLLAQAVDRASNRPLEPPSEFIIKVQDINDNPPIFPLGPYHATVP 160
Query: 170 EMSDMGTSVLQVTATDADDPTYGNSARVVYSILQGQPYFSVDPKTGVIRTALHNMDREAR 229
EMS++GTSV+QVTA DADDP+YGNSA++VY++L G P+FSVDP+TGV+RTA+ NMDRE +
Sbjct: 161 EMSNVGTSVIQVTAHDADDPSYGNSAKLVYTVLDGLPFFSVDPQTGVVRTAIPNMDRETQ 220
Query: 230 EHYSVVIQAKDMAGQVGGLSGSTTVNITLTDVNDNPPRFPQKHYQLYVPESAQVGSAVGK 289
E + VVIQAKDM G +GGLSGSTTV +TL+DVNDNPP+FPQ YQ V E+A G+ VG+
Sbjct: 221 EEFLVVIQAKDMGGHMGGLSGSTTVTVTLSDVNDNPPKFPQSLYQFSVVETAGPGTLVGR 280
Query: 290 IKANDADTGSNADMTYSIINGDGMGIFSISTDKETREGILSLKKPLNYEKKKSYTLNIEG 349
++A D D G NA M YSI++G+G FSISTD + R+G+L+++KPL++E ++SY+ +E
Sbjct: 281 LRAQDPDLGDNALMAYSILDGEGSEAFSISTDLQGRDGLLTVRKPLDFESQRSYSFRVEA 340
Query: 350 ANTHLDFRFSHLGPFKDATMLKIIVGDVDEPPLFSMPSYLMEVYENAKIGTVVGTVLAQD 409
NT +D + GPFKD +++ V D EPP F+ +Y + V EN GT+VG + A D
Sbjct: 341 TNTLIDPAYLRRGPFKDVASVRVAVQDAPEPPAFTQAAYHLTVPENKAPGTLVGQISAAD 400
Query: 410 PDSTNSLVRYFINYNVEDDRFFNIDANTGTIRTTKVLDREETPWYNITVTASEI------ 463
DS S +RY I + + +R F+I GTI T LDRE W+N+TV A+E+
Sbjct: 401 LDSPASPIRYSILPHSDPERCFSIQPEEGTIHTAAPLDREARAWHNLTVLATELGWSWGP 460
Query: 464 --------------------------------DNPDLLSHVTVGIRVLDVNDNPPELARE 491
D+ S V V I+ LD NDN P+LA
Sbjct: 461 ERGWVPLLVAEWSAPAAPPQRSPVGSAVGIPQDSSAQASRVQVAIQTLDENDNAPQLAEP 520
Query: 492 YDIIVCENSKPGQVIHTISATDKDDFANGPRFNFFLDERLPVNP--NFTLKDNEDNTASI 549
YD VC+++ PGQ+I I A D+D+ N +F + P+ P NFT++DN D +AS+
Sbjct: 521 YDTFVCDSAAPGQLIQVIRALDRDEVGNSSHVSF----QGPLGPDANFTVQDNRDGSASL 576
Query: 550 LTRRRRFSRTVQDVYYLPIMISDGGIPSLSSSSTLTIRVCACERDGRVRTCHAEAFLSSA 609
L R + Y +PI + D G P+LSS++T+T+ VC C+ DG V +C EA LS+A
Sbjct: 577 LLPSRP-APPRHAPYLVPIELWDWGQPALSSTATVTVSVCRCQPDGSVASCWPEAHLSAA 635
Query: 610 GLSTGALIAILLCVLILLAIVVLFITLRRSKKEPL-IISEEDVRENVVTYDDEGGGEEDT 668
GLSTGAL+AI+ CV LLA+VVLF+ LRR K+E L ++ EEDVREN++TYDDEGGGEEDT
Sbjct: 636 GLSTGALLAIITCVGALLALVVLFVALRRQKQEALMVLEEEDVRENIITYDDEGGGEEDT 695
Query: 669 EAFDITALRNPSAAEE----LKYRRDIRPEVKLTPRHQTSSTLESIDVQEFIKQRLAEAD 724
EAFDITAL+NP A RRD+ P +++ + + DV + + RL EAD
Sbjct: 696 EAFDITALQNPDGAAPPAPGPPARRDVLPRARVSRQPRPPG---PADVAQLLALRLREAD 752
Query: 725 LDPSVPPYDSLQTYAYEGQRSEAGSISSLDSATTQ--SDQDYHYLGDWGPEFKKLAELYG 782
DP VPPYDS+Q Y YEG+ S GS+SSL S + + L DWGP F+ LAELYG
Sbjct: 753 EDPGVPPYDSVQVYGYEGRGSSCGSLSSLGSGSEAGGAPGPAEPLDDWGPLFRTLAELYG 812
Query: 783 EIE 785
E
Sbjct: 813 AKE 815
>gi|12656655 cadherin 19, type 2 preproprotein [Homo sapiens]
Length = 772
Score = 679 bits (1751), Expect = 0.0
Identities = 359/748 (47%), Positives = 493/748 (65%), Gaps = 9/748 (1%)
Query: 36 NQTKHIEGETEVHHRPKRGWVWNQFFVLEEHMGPDPQYVGKLHSNSDKGDGSVKYILTGE 95
+QTK ++ H R KRGWVWNQFFV EE M ++G+L S+ D G+ S +Y L G
Sbjct: 26 SQTKKVKQPVRSHLRVKRGWVWNQFFVPEE-MNTTSHHIGQLRSDLDNGNNSFQYKLLGA 84
Query: 96 GAGTIFIIDDTTGDIHSTKSLDREQKTHYVLHAQAIDRRTNKPLEPESEFIIKVQDINDN 155
GAG+ FIID+ TGDI++ + LDRE+++ Y+L AQ ID T + +EPESEF+IKV DINDN
Sbjct: 85 GAGSTFIIDERTGDIYAIQKLDREERSLYILRAQVIDIATGRAVEPESEFVIKVSDINDN 144
Query: 156 APKFTDGPYIVTVPEMSDMGTSVLQVTATDADDPTYGNSARVVYSILQGQPYFSVDPKTG 215
PKF D PY VPEMS GT V+QVTA+DADDP+ GN+AR++YS+LQGQPYFSV+P TG
Sbjct: 145 EPKFLDEPYEAIVPEMSPEGTLVIQVTASDADDPSSGNNARLLYSLLQGQPYFSVEPTTG 204
Query: 216 VIRTALHNMDREAREHYSVVIQAKDMAGQVGGLSGSTTVNITLTDVNDNPPRFPQKHYQL 275
VIR + MDRE ++ Y V+IQAKDM GQ G LSG+T+V I L+DVNDN P F + Y+L
Sbjct: 205 VIRIS-SKMDRELQDEYWVIIQAKDMIGQPGALSGTTSVLIKLSDVNDNKPIFKESLYRL 263
Query: 276 YVPESAQVGSAVGKIKANDADTGSNADMTYSIINGDGMGIFSISTDKETREGILSLKKPL 335
V ESA G+++G I A D D G NA+M YSI D F I T+ ET+EGI+ LKK +
Sbjct: 264 TVSESAPTGTSIGTIMAYDNDIGENAEMDYSIEEDDSQ-TFDIITNHETQEGIVILKKKV 322
Query: 336 NYEKKKSYTLNIEGANTHLDFRFSHLGPFKDATMLKIIVGDVDEPPLFSMPSYLMEVYEN 395
++E + Y + + N H+ + T +KI V DVDEPPLF +P Y+ EV+E
Sbjct: 323 DFEHQNHYGIRAKVKNHHVPEQLMKYHTEASTTFIKIQVEDVDEPPLFLLPYYVFEVFEE 382
Query: 396 AKIGTVVGTVLAQDPDSTNSLVRYFINYNVEDDRFFNIDANTGTIRTTKVLDREETPWYN 455
G+ VG V A DPD+ S +R Y++ + FNI+ N GTI T+ LDRE + WYN
Sbjct: 383 TPQGSFVGVVSATDPDNRKSPIR----YSITRSKVFNINDN-GTITTSNSLDREISAWYN 437
Query: 456 ITVTASEIDNPDLLSHVTVGIRVLDVNDNPPELAREYDIIVCENSKPGQVIHTISATDKD 515
+++TA+E N + +S + + ++VL++ND+ PE ++ Y+ VCEN+ GQVI TISA D+D
Sbjct: 438 LSITATEKYNIEQISSIPLYVQVLNINDHAPEFSQYYETYVCENAGSGQVIQTISAVDRD 497
Query: 516 DFANGPRFNFFLDERLPVNPNFTLKDNEDNTASILTRRRRFSRTVQDVYYLPIMISDGGI 575
+ F F L N +FT+ DN+DNTA ILT R F+ + V+Y+ I+I+D GI
Sbjct: 498 ESIEEHHFYFNLSVEDTNNSSFTIIDNQDNTAVILTNRTGFNLQEEPVFYISILIADNGI 557
Query: 576 PSLSSSSTLTIRVCACERDGRVRTCHAEAFLSSAGLSTGALIAILLCVLILLAIVVLFIT 635
PSL+S++TLTI VC C G +TC + + S G T +IAIL+C++I+ + L +
Sbjct: 558 PSLTSTNTLTIHVCDCGDSGSTQTCQYQELVLSMGFKTEVIIAILICIMIIFGFIFLTLG 617
Query: 636 LRRSKKEPLIISE-EDVRENVVTYDDEGGGEEDTEAFDITALRNPSAAEELKYRRDIRPE 694
L++ +K+ L + ED REN+ YDDEGGGEEDTEAFDI LR+ + E K R+ E
Sbjct: 618 LKQRRKQILFPEKSEDFRENIFQYDDEGGGEEDTEAFDIAELRSSTIMRERKTRKTTSAE 677
Query: 695 VKLTPRHQTSSTLESIDVQEFIKQRLAEADLDPSVPPYDSLQTYAYEGQRSEAGSISSLD 754
++ R +S ++FI ++L EA+ DP PP+DSLQTYA+EG S AGS+SSL+
Sbjct: 678 IRSLYRQSLQVGPDSAIFRKFILEKLEEANTDPCAPPFDSLQTYAFEGTGSLAGSLSSLE 737
Query: 755 SATTQSDQDYHYLGDWGPEFKKLAELYG 782
SA + D+ Y YL + GP FK+LA ++G
Sbjct: 738 SAVSDQDESYDYLNELGPRFKRLACMFG 765
>gi|166362713 cadherin 5, type 2 preproprotein [Homo sapiens]
Length = 784
Score = 536 bits (1382), Expect = e-152
Identities = 309/747 (41%), Positives = 430/747 (57%), Gaps = 25/747 (3%)
Query: 48 HHRPKRGWVWNQFFVLEEHMGPDPQYVGKLHSNSDKGDGSVKYILTGEGAGTIFIIDDTT 107
H R KR W+WNQ + EE P +VGK+ S+ + + KY+L GE G +F +D T
Sbjct: 42 HRRQKRDWIWNQMHIDEEKNTSLPHHVGKIKSSVSRKNA--KYLLKGEYVGKVFRVDAET 99
Query: 108 GDIHSTKSLDREQKTHYVLHAQAIDRRTNKPLEPESEFIIKVQDINDNAPKFTDGPYIVT 167
GD+ + + LDRE + Y L A +D+ T + LE S F IKV D+NDN P FT + +
Sbjct: 100 GDVFAIERLDRENISEYHLTAVIVDKDTGENLETPSSFTIKVHDVNDNWPVFTHRLFNAS 159
Query: 168 VPEMSDMGTSVLQVTATDADDPTYGNSARVVYSILQGQPYFSVDPKTGVIRTALHNMDRE 227
VPE S +GTSV+ VTA DADDPT G+ A V+Y IL+G+ YF++D +G I T ++DRE
Sbjct: 160 VPESSAVGTSVISVTAVDADDPTVGDHASVMYQILKGKEYFAID-NSGRIITITKSLDRE 218
Query: 228 AREHYSVVIQAKDMAGQVGGLSGSTTVNITLTDVNDNPPRFPQKHYQLYVPESAQVGSAV 287
+ Y +V++A+D G + G SG+ TV +TL D+NDN P F Q Y VPE +VG++V
Sbjct: 219 KQARYEIVVEARDAQG-LRGDSGTATVLVTLQDINDNFPFFTQTKYTFVVPEDTRVGTSV 277
Query: 288 GKIKANDADTGSNADMTYSIINGDGMGIFSISTDKETREGILSLKKPLNYEKKKSYTLNI 347
G + D D N YSI+ GD F+I T+ EGI+ KPL+YE + Y+ +
Sbjct: 278 GSLFVEDPDEPQNRMTKYSILRGDYQDAFTIETNPAHNEGIIKPMKPLDYEYIQQYSFIV 337
Query: 348 EGANTHLDFRFSHLGPFKDATMLKIIVGDVDEPPLFSMPSYLMEVYENAKIGTVVGTVLA 407
E + +D R+ P + + I + DVDEPP+F P Y ++ EN K ++GTVLA
Sbjct: 338 EATDPTIDLRYMS-PPAGNRAQVIINITDVDEPPIFQQPFYHFQLKENQK-KPLIGTVLA 395
Query: 408 QDPDSTNSLVRYFINYNVEDDRFFNIDANTGTIRTTKVLDREETPWYNITVTASEIDNPD 467
DPD+ + Y I + +FF + G I K LDRE PWYN+TV A E+D+
Sbjct: 396 MDPDAARHSIGYSIRRTSDKGQFFRV-TKKGDIYNEKELDREVYPWYNLTVEAKELDSTG 454
Query: 468 L----LSHVTVGIRVLDVNDNPPELAREYDIIVCENSKPGQVIHTISATDKDDFANGPRF 523
S V V I VLD NDN PE A+ Y VCEN+ GQ++ ISA DKD +F
Sbjct: 455 TPTGKESIVQVHIEVLDENDNAPEFAKPYQPKVCENAVHGQLVLQISAIDKDITPRNVKF 514
Query: 524 NFFLDERLPVNPNFTLKDNEDNTASILTRRRRFSRTVQDVYYLPIMISDGGIPSLSSSST 583
F L+ NFTL DN DNTA+I + +F R V++LP++ISD G+PS + +ST
Sbjct: 515 KFILN----TENNFTLTDNHDNTANITVKYGQFDREHTKVHFLPVVISDNGMPSRTGTST 570
Query: 584 LTIRVCACERDGRVRTCHAEAFLSSAGLSTGALIAILLCVLILLAIVVLFITLRRSKKEP 643
LT+ VC C G C E + G+S A++AILLC+L + I +L RR +K+
Sbjct: 571 LTVAVCKCNEQGEFTFC--EDMAAQVGVSIQAVVAILLCILTITVITLLIFLRRRLRKQA 628
Query: 644 LI--ISEEDVRENVVTYDDEGGGEEDTEAFDITALRN--PSAAEELKYRRDIRP----EV 695
S ++ E +VTYD+EGGGE DT ++D++ L + A+ + D RP +V
Sbjct: 629 RAHGKSVPEIHEQLVTYDEEGGGEMDTTSYDVSVLNSVRRGGAKPPRPALDARPSLYAQV 688
Query: 696 KLTPRHQTSSTLESIDVQEFIKQRLAEADLDPSVPPYDSLQTYAYEGQRSEAGSISSLDS 755
+ PRH + ++ I+ + EAD D PPYD+L Y YEG S A S+SSL +
Sbjct: 689 QKPPRHAPGAHGGPGEMAAMIEVKKDEADHDGDGPPYDTLHIYGYEGSESIAESLSSLGT 748
Query: 756 ATTQSDQDYHYLGDWGPEFKKLAELYG 782
++ SD DY +L DWGP FK LAELYG
Sbjct: 749 DSSDSDVDYDFLNDWGPRFKMLAELYG 775
>gi|14589893 cadherin 4, type 1 preproprotein [Homo sapiens]
Length = 916
Score = 397 bits (1021), Expect = e-110
Identities = 283/770 (36%), Positives = 415/770 (53%), Gaps = 51/770 (6%)
Query: 50 RPKRGWVWNQFFVLEEHMGPDPQYVGKLHSNSDKGDGSVKYILTGEGAGT----IFIIDD 105
R KR WV V E GP PQ + ++ S+ D D ++Y +TG GA +F ID
Sbjct: 166 RRKRDWVIPPINVPENSRGPFPQQLVRIRSDKDN-DIPIRYSITGVGADQPPMEVFSIDS 224
Query: 106 TTGDIHSTKSLDREQKTHYVLHAQAIDRRTNKPLEPESEFIIKVQDINDNAPKFTDGPYI 165
+G ++ T+ +DRE+ Y L A A+D NK +E + I V D+NDN P+F + Y
Sbjct: 225 MSGRMYVTRPMDREEHASYHLRAHAVDMNGNK-VENPIDLYIYVIDMNDNRPEFINQVYN 283
Query: 166 VTVPEMSDMGTSVLQVTATDADDPTYGNSA---RVVYSILQG--QPYFSVDPKTGVIRTA 220
+V E S GT V+ VTA DADD T N R+V Q Q F+++ +TG I T
Sbjct: 284 GSVDEGSKPGTYVMTVTANDADDSTTANGMVRYRIVTQTPQSPSQNMFTINSETGDIVTV 343
Query: 221 LHNMDREAREHYSVVIQAKDMAGQVG-GLSGSTTVNITLTDVNDNPPRFPQKHYQLYVPE 279
+DRE + Y+V++QA DM G + GLS + T IT+TDVNDNPP F + VPE
Sbjct: 344 AAGLDREKVQQYTVIVQATDMEGNLNYGLSNTATAIITVTDVNDNPPEFTASTFAGEVPE 403
Query: 280 SAQVGSAVGKIKANDADT--GSNADMTYSIINGDGMGIFSISTDKETREGILSLKKPLNY 337
+ +V + V + D D N + Y II+GD G FS+ TD T EG++++ K ++Y
Sbjct: 404 N-RVETVVANLTVMDRDQPHSPNWNAVYRIISGDPSGHFSVRTDPVTNEGMVTVVKAVDY 462
Query: 338 EKKKSYTLNIEGANTHLDFRFSHLGPFKDATMLKIIVGDVDEPPLFSMPSYLMEVYENAK 397
E +++ L + +N F+ + I + D++E P F L+ + E
Sbjct: 463 ELNRAFMLTVMVSN-QAPLASGIQMSFQSTAGVTISIMDINEAPYFPSNHKLIRLEEGVP 521
Query: 398 IGTVVGTVLAQDPDSTNSLVRYFINYNVEDD--RFFNIDANTGTIRTTKVLDRE----ET 451
GTV+ T A DPD ++ + Y+ D + +I+A G I T VLDRE +
Sbjct: 522 PGTVLTTFSAVDPDR---FMQQAVRYSKLSDPASWLHINATNGQITTAAVLDRESLYTKN 578
Query: 452 PWYNITVTASEIDNPDLLSHVTVGIRVLDVNDNPPELAREYDIIVCENSKPGQVIHTISA 511
Y T A++ P T+ I ++D+NDN PEL + + +CE KP I+A
Sbjct: 579 NVYEATFLAADNGIPPASGTGTLQIYLIDINDNAPELLPK-EAQICE--KPNLNAINITA 635
Query: 512 TDKDDFANGPRFNFFLD-ERLPVNPNFTLKDNEDNTASILTRRRRFSRTVQDVYYLPIMI 570
D D N + F L V N+T+ + A + R + DV PI++
Sbjct: 636 ADADVDPNIGPYVFELPFVPAAVRKNWTITRLNGDYAQLSLRILYLEAGMYDV---PIIV 692
Query: 571 SDGGIPSLSSSSTLTIRVCACERDGRVRTCHAEAFLSSAGLSTGALIAILLCVLILLAIV 630
+D G P LS++S + ++VC C+ +G T A A +AGL TGA++AIL+C+LILL +V
Sbjct: 693 TDSGNPPLSNTSIIKVKVCPCDDNGDCTTIGAVA---AAGLGTGAIVAILICILILLTMV 749
Query: 631 VLFITL--RRSK----KEPLIISEEDVRENVVTYDDEGGGEEDTEAFDITALRNPSAAEE 684
+LF+ RR K K+ LI E+DVR+N++ YD+EGGGEED + +D++ L+ P A
Sbjct: 750 LLFVMWMKRREKERHTKQLLIDPEDDVRDNILKYDEEGGGEEDQD-YDLSQLQQPEAMGH 808
Query: 685 LKY------RRDIRPEVKLTPRHQTSSTLESI-DVQEFIKQRLAEADLDPSVPPYDSLQT 737
+ R D RP V P++ + D+ +FI + L AD DP+ PPYDSL
Sbjct: 809 VPSKAPGVRRVDERP-VGAEPQYPIRPMVPHPGDIGDFINEGLRAADNDPTAPPYDSLLV 867
Query: 738 YAYEGQRSEAGSISSLDSATTQSDQDYHYLGDWGPEFKKLAELYGEIESE 787
+ YEG S AGS+SSL+S+++ DQDY YL DWGP FKKLA++YG E +
Sbjct: 868 FDYEGSGSTAGSVSSLNSSSS-GDQDYDYLNDWGPRFKKLADMYGGGEED 916
>gi|14589889 cadherin 2, type 1 preproprotein [Homo sapiens]
Length = 906
Score = 397 bits (1020), Expect = e-110
Identities = 279/767 (36%), Positives = 407/767 (53%), Gaps = 54/767 (7%)
Query: 50 RPKRGWVWNQFFVLEEHMGPDPQYVGKLHSNSDKGDGSVKYILTGEGAGT----IFIIDD 105
R KR WV + E GP PQ + ++ S+ DK + S++Y +TG GA IFII+
Sbjct: 156 RQKRDWVIPPINLPENSRGPFPQELVRIRSDRDK-NLSLRYSVTGPGADQPPTGIFIINP 214
Query: 106 TTGDIHSTKSLDREQKTHYVLHAQAIDRRTNKPLEPESEFIIKVQDINDNAPKFTDGPYI 165
+G + TK LDREQ + L A A+D N+ +E + +I V D+NDN P+F +
Sbjct: 215 ISGQLSVTKPLDREQIARFHLRAHAVDINGNQ-VENPIDIVINVIDMNDNRPEFLHQVWN 273
Query: 166 VTVPEMSDMGTSVLQVTATDADDPTYGNSARVVYSILQGQP------YFSVDPKTGVIRT 219
TVPE S GT V+ VTA DADDP N + Y I+ P F+++ +TG I T
Sbjct: 274 GTVPEGSKPGTYVMTVTAIDADDPNALNGM-LRYRIVSQAPSTPSPNMFTINNETGDIIT 332
Query: 220 ALHNMDREAREHYSVVIQAKDMAGQ-VGGLSGSTTVNITLTDVNDNPPRFPQKHYQLYVP 278
+DRE + Y+++IQA DM G GLS + T IT+TDVNDNPP F + VP
Sbjct: 333 VAAGLDREKVQQYTLIIQATDMEGNPTYGLSNTATAVITVTDVNDNPPEFTAMTFYGEVP 392
Query: 279 ESAQVGSAVGKIKANDADTGSNA--DMTYSIINGDGMGIFSISTDKETREGILSLKKPLN 336
E+ +V V + D D + Y I GD G F+I TD + +G++++ KP++
Sbjct: 393 EN-RVDIIVANLTVTDKDQPHTPAWNAVYRISGGDPTGRFAIQTDPNSNDGLVTVVKPID 451
Query: 337 YEKKKSYTLNIEGAN-THLDFRFSHLGPFKDATMLKIIVGDVDEPPLFSMPSYLMEVYEN 395
+E + + L + N L H P + + + V DV+E P F+ ++ E
Sbjct: 452 FETNRMFVLTVAAENQVPLAKGIQH--PPQSTATVSVTVIDVNENPYFAPNPKIIRQEEG 509
Query: 396 AKIGTVVGTVLAQDPDSTNSLVRYFINYNVEDD--RFFNIDANTGTIRTTKVLDRE---- 449
GT++ T AQDPD ++ I Y D + ID G I T VLDRE
Sbjct: 510 LHAGTMLTTFTAQDPDR---YMQQNIRYTKLSDPANWLKIDPVNGQITTIAVLDRESPNV 566
Query: 450 ETPWYNITVTASEIDNPDLLSHVTVGIRVLDVNDNPPELAREYDIIVCENSKPGQVIHTI 509
+ YN T AS+ P + T+ I +LD+NDN P++ + + CE P + I
Sbjct: 567 KNNIYNATFLASDNGIPPMSGTGTLQIYLLDINDNAPQVLPQ-EAETCETPDPNSI--NI 623
Query: 510 SATDKDDFANGPRFNFFLD-ERLPVNPNFTLKDNEDNTASILTRRRRFSRTVQDVYYLPI 568
+A D D N F F L + + N+T+ + A L + +F +Y +PI
Sbjct: 624 TALDYDIDPNAGPFAFDLPLSPVTIKRNWTITRLNGDFAQ-LNLKIKFLEA--GIYEVPI 680
Query: 569 MISDGGIPSLSSSSTLTIRVCACERDGRVRTCHAEAFLSSAGLSTGALIAILLCVLILLA 628
+I+D G P S+ S L ++VC C+ +G C + AGL TGA+IAILLC++ILL
Sbjct: 681 IITDSGNPPKSNISILRVKVCQCDSNG---DCTDVDRIVGAGLGTGAIIAILLCIIILLI 737
Query: 629 IVVLFITL------RRSKKEPLIISEEDVRENVVTYDDEGGGEEDTEAFDITALRNPSAA 682
+V++F+ R K+ LI E+DVR+N++ YD+EGGGEED + +D++ L+ P
Sbjct: 738 LVLMFVVWMKRRDKERQAKQLLIDPEDDVRDNILKYDEEGGGEEDQD-YDLSQLQQPDTV 796
Query: 683 EELKY------RRDIRPEVKLTPRHQTSSTLESI-DVQEFIKQRLAEADLDPSVPPYDSL 735
E R D RP + P++ S D+ +FI + L AD DP+ PPYDSL
Sbjct: 797 EPDAIKPVGIRRMDERP-IHAEPQYPVRSAAPHPGDIGDFINEGLKAADNDPTAPPYDSL 855
Query: 736 QTYAYEGQRSEAGSISSLDSATTQSDQDYHYLGDWGPEFKKLAELYG 782
+ YEG S AGS+SSL+S+++ +QDY YL DWGP FKKLA++YG
Sbjct: 856 LVFDYEGSGSTAGSLSSLNSSSSGGEQDYDYLNDWGPRFKKLADMYG 902
>gi|4757960 cadherin 1, type 1 preproprotein [Homo sapiens]
Length = 882
Score = 373 bits (958), Expect = e-103
Identities = 271/783 (34%), Positives = 406/783 (51%), Gaps = 50/783 (6%)
Query: 27 HHSSIKVMRNQTKHIEGETEVHHRPKRGWVWNQFFVLEEHMGPDPQYVGKLHSNSDKGDG 86
H +S+ ++ + + R KR WV E GP P+ + ++ SN DK +G
Sbjct: 128 HQASVSGIQAELLTFPNSSPGLRRQKRDWVIPPISCPENEKGPFPKNLVQIKSNKDK-EG 186
Query: 87 SVKYILTGEGAGT----IFIIDDTTGDIHSTKSLDREQKTHYVLHAQAIDRRTNKPLEPE 142
V Y +TG+GA T +FII+ TG + T+ LDRE+ Y L + A+ N +P
Sbjct: 187 KVFYSITGQGADTPPVGVFIIERETGWLKVTEPLDRERIATYTLFSHAVSSNGNAVEDP- 245
Query: 143 SEFIIKVQDINDNAPKFTDGPYIVTVPEMSDMGTSVLQVTATDADDPTYGNSARVVYSIL 202
E +I V D NDN P+FT + +V E + GTSV++VTATDADD +A + Y+IL
Sbjct: 246 MEILITVTDQNDNKPEFTQEVFKGSVMEGALPGTSVMEVTATDADDDVNTYNAAIAYTIL 305
Query: 203 QGQP------YFSVDPKTGVIRTALHNMDREAREHYSVVIQAKDMAGQVGGLSGSTTVNI 256
P F+++ TGVI +DRE+ Y++V+QA D+ G+ GLS + T I
Sbjct: 306 SQDPELPDKNMFTINRNTGVISVVTTGLDRESFPTYTLVVQAADLQGE--GLSTTATAVI 363
Query: 257 TLTDVNDNPPRFPQKHYQLYVPESAQVGSAVGKIKANDADTGSNA--DMTYSIINGDGMG 314
T+TD NDNPP F Y+ VPE+ + + +K DAD + + Y+I+N DG G
Sbjct: 364 TVTDTNDNPPIFNPTTYKGQVPEN-EANVVITTLKVTDADAPNTPAWEAVYTILNDDG-G 421
Query: 315 IFSISTDKETREGILSLKKPLNYEKKKSYTLNIEGANTHLDFRFSHLGPFKDATMLKIIV 374
F ++T+ +GIL K L++E K+ Y L++ N + F S T + V
Sbjct: 422 QFVVTTNPVNNDGILKTAKGLDFEAKQQYILHVAVTNV-VPFEVSLTTSTATVT---VDV 477
Query: 375 GDVDEPPLFSMPSYLMEVYENAKIGTVVGTVLAQDPDSTNSLVRYFINYNVEDD--RFFN 432
DV+E P+F P +EV E+ +G + + AQ+PD+ + I Y + D +
Sbjct: 478 LDVNEAPIFVPPEKRVEVSEDFGVGQEITSYTAQEPDT---FMEQKITYRIWRDTANWLE 534
Query: 433 IDANTGTIRTTKVLDREE-----TPWYNITVTASEIDNPDLLSHVTVGIRVLDVNDNPPE 487
I+ +TG I T LDRE+ Y + A++ +P T+ + + DVNDN P
Sbjct: 535 INPDTGAISTRAELDREDFEHVKNSTYTALIIATDNGSPVATGTGTLLLILSDVNDNAP- 593
Query: 488 LAREYDIIVCENSKPGQVIHTISATDKDDFANGPRFNFFLDERLPVNPNFTLKDNEDNTA 547
+ I CE + QVI+ I D D N F L + N+T++ N+
Sbjct: 594 IPEPRTIFFCERNPKPQVINII---DADLPPNTSPFTAELTHG--ASANWTIQYNDPTQE 648
Query: 548 SILTRRRRFSRTVQDVYYLPIMISDGGIPSLSSSSTLTIRVCACERDGRVRTCHAEAFLS 607
SI+ + + + V D Y + + + D + +TL + VC CE G C +A
Sbjct: 649 SIILKPK-MALEVGD-YKINLKLMDN--QNKDQVTTLEVSVCDCE--GAAGVCR-KAQPV 701
Query: 608 SAGLSTGALIAIL---LCVLILLAIVVLFITLRRSKKEPLIISEEDVRENVVTYDDEGGG 664
AGL A++ IL L +LIL+ +++LF+ R KEPL+ E+D R+NV YD+EGGG
Sbjct: 702 EAGLQIPAILGILGGILALLILILLLLLFLRRRAVVKEPLLPPEDDTRDNVYYYDEEGGG 761
Query: 665 EEDTEAFDITALRNPSAAEELKYRRDIRPEVKLTPRHQTSSTLESIDVQEFIKQRLAEAD 724
EED + FD++ L A R D+ P + PR+ ++ FI + L AD
Sbjct: 762 EEDQD-FDLSQLHRGLDARPEVTRNDVAPTLMSVPRYLPRPANPD-EIGNFIDENLKAAD 819
Query: 725 LDPSVPPYDSLQTYAYEGQRSEAGSISSLDSATTQSDQDYHYLGDWGPEFKKLAELYGEI 784
DP+ PPYDSL + YEG SEA S+SSL+S+ + DQDY YL +WG FKKLA++YG
Sbjct: 820 TDPTAPPYDSLLVFDYEGSGSEAASLSSLNSSESDKDQDYDYLNEWGNRFKKLADMYGGG 879
Query: 785 ESE 787
E +
Sbjct: 880 EDD 882
>gi|4826669 cadherin 15 preproprotein [Homo sapiens]
Length = 814
Score = 364 bits (934), Expect = e-100
Identities = 259/756 (34%), Positives = 380/756 (50%), Gaps = 39/756 (5%)
Query: 50 RPKRGWVWNQFFVLEEHMG-PDPQYVGKLHSNSDKGD-GSVKYILTGEGAGT----IFII 103
R +R WV V E H P P + SDK GSV Y + G G +F I
Sbjct: 42 RVRRAWVIPPISVSENHKRLPYPL----VQIKSDKQQLGSVIYSIQGPGVDEEPRGVFSI 97
Query: 104 DDTTGDIHSTKSLDREQKTHYVLHAQAIDRRTNKPLEPESEFIIKVQDINDNAPKFTDGP 163
D TG + LDRE+ + L A A+D LE ++ I V D NDN P F
Sbjct: 98 DKFTGKVFLNAMLDREKTDRFRLRAFALDLG-GSTLEDPTDLEIVVVDQNDNRPAFLQEA 156
Query: 164 YIVTVPEMSDMGTSVLQVTATDADDPTYGNSARVVYSILQGQP-YFSVDPKTGVIRTALH 222
+ V E + GT V + ATDADDP N+A + QG P FS+D TG IRT
Sbjct: 157 FTGRVLEGAVPGTYVTRAEATDADDPETDNAALRFSILQQGSPELFSIDELTGEIRTVQV 216
Query: 223 NMDREAREHYSVVIQAKDMAGQVGGLSGSTTVNITLTDVNDNPPRFPQKHYQLYVPESAQ 282
+DRE Y++ +Q DM+G GL+ + + ITL D+NDN P F + + + E+
Sbjct: 217 GLDREVVAVYNLTLQVADMSGD--GLTATASAIITLDDINDNAPEFTRDEFFMEAIEAVS 274
Query: 283 VGSAVGKIKANDADTGSNADMT--YSIINGDGMGIFSISTDKETREGILSLKKPLNYEKK 340
G VG+++ D D + + ++I+ GD G F+I TD +T EG+LS+ K L+YE
Sbjct: 275 -GVDVGRLEVEDRDLPGSPNWVARFTILEGDPDGQFTIRTDPKTNEGVLSIVKALDYESC 333
Query: 341 KSYTLNIEGANTHLDFRFSHLGPFKDATMLKIIVGDVDEPPLFSMPSYLMEVYENAKIGT 400
+ Y L + N + + L + +++ V D +EPP+F + E A GT
Sbjct: 334 EHYELKVSVQN-EAPLQAAALRAERGQAKVRVHVQDTNEPPVFQENPLRTSLAEGAPPGT 392
Query: 401 VVGTVLAQDPDSTNSLVRYFINYNVEDDRFFNIDANTGTIRTTKVLDREET----PWYNI 456
+V T A+DPD T L R + + + + + +DA TG I+T VL WY
Sbjct: 393 LVATFSARDPD-TEQLQRLSYSKDYDPEDWLQVDAATGRIQTQHVLSPASPFLKGGWYRA 451
Query: 457 TVTASEIDNPDLLSHVTVGIRVLDVNDNPPELAREYDIIVCENSKPGQVIHTISATDKDD 516
V A + + + T+ I +L+VND+ P LA +C G + + ATD+D
Sbjct: 452 IVLAQDDASQPRTATGTLSIEILEVNDHAPVLAPPPPGSLCSEPHQGPGL-LLGATDEDL 510
Query: 517 FANGPRFNFFLDERLP-VNPNFTLKDNEDNTASILTRRRRFSRTVQDVYYLPIMISDGGI 575
+G F+F L RLP + N++L + A + R + + ++ L +++ D G
Sbjct: 511 PPHGAPFHFQLSPRLPELGRNWSLSQVNVSHARLRPRHQ----VPEGLHRLSLLLRDSGQ 566
Query: 576 PSLSSSSTLTIRVCACERDGRVRTCHAEAFLSSAGLSTGALIAILLCVLILLAIVVLFIT 635
P L + VC C +DG A GLS GAL+ +L L+LL +V+L
Sbjct: 567 PPQQREQPLNVTVCRCGKDGVCLPGAAALLAGGTGLSLGALVIVLASALLLLVLVLLVAL 626
Query: 636 LRRSKKEP-----LIISEEDVRENVVTYDDEGGGEEDTEAFDITALRNPSAAE----ELK 686
R K+ L ++D+R+NV+ YD++GGGEED +A+DI+ LR+P+A
Sbjct: 627 RARFWKQSRGKGLLHGPQDDLRDNVLNYDEQGGGEEDQDAYDISQLRHPTALSLPLGPPP 686
Query: 687 YRRDIRPEVKLTPRHQTSSTLESIDVQEFIKQRLAEADLDPSVPPYDSLQTYAYEGQRSE 746
RRD P+ +L P+ +D+ +FI L AD DPSVPPYD+ Y YEG S
Sbjct: 687 LRRDA-PQGRLHPQPPRVLPTSPLDIADFINDGLEAADSDPSVPPYDTALIYDYEGDGSV 745
Query: 747 AGSISSLDSATTQSDQDYHYLGDWGPEFKKLAELYG 782
AG++SS+ S+ DQDY YL DWGP F +LA++YG
Sbjct: 746 AGTLSSILSSQGDEDQDYDYLRDWGPRFARLADMYG 781
>gi|14589891 cadherin 3, type 1 preproprotein [Homo sapiens]
Length = 829
Score = 357 bits (917), Expect = 2e-98
Identities = 260/759 (34%), Positives = 385/759 (50%), Gaps = 54/759 (7%)
Query: 50 RPKRGWVWNQFFVLEEHMGPDPQYVGKLHSNSDKGDGSVKYILTGEGAGT----IFIIDD 105
R KR WV V E GP PQ + +L SN D+ D + Y +TG GA + +F ++
Sbjct: 104 RHKRDWVVAPISVPENGKGPFPQRLNQLKSNKDR-DTKIFYSITGPGADSPPEGVFAVEK 162
Query: 106 TTGDIHSTKSLDREQKTHYVLHAQAIDRRTNKPLEPESEFIIKVQDINDNAPKFTDGPYI 165
TG + K LDRE+ Y L A+ +P + II V D ND+ PKFT +
Sbjct: 163 ETGWLLLNKPLDREEIAKYELFGHAVSENGASVEDPMNISII-VTDQNDHKPKFTQDTFR 221
Query: 166 VTVPEMSDMGTSVLQVTATDADDPTYGNSARVVYSILQGQP------YFSVDPKTGVIRT 219
+V E GTSV+QVTATD DD Y + V YSI +P F++ TG I
Sbjct: 222 GSVLEGVLPGTSVMQVTATDEDDAIYTYNGVVAYSIHSQEPKDPHDLMFTIHRSTGTISV 281
Query: 220 ALHNMDREAREHYSVVIQAKDMAGQVGGLSGSTTVNITLT---DVNDNPPRFPQKHYQLY 276
+DRE Y++ IQA DM G GSTT + + D NDN P F + Y+ +
Sbjct: 282 ISSGLDREKVPEYTLTIQATDMDGD-----GSTTTAVAVVEILDANDNAPMFDPQKYEAH 336
Query: 277 VPESAQVGSAVGKIKANDADTGSNADM--TYSIINGDGMGIFSISTDKETREGILSLKKP 334
VPE+A VG V ++ D D ++ TY I+ GD F+I+T E+ +GIL+ +K
Sbjct: 337 VPENA-VGHEVQRLTVTDLDAPNSPAWRATYLIMGGDDGDHFTITTHPESNQGILTTRKG 395
Query: 335 LNYEKKKSYTLNIEGANTHLDFRFSHLGPFKDATMLKIIVGDVDEPPLFSMPSYLMEVYE 394
L++E K +TL +E N + F P AT++ + V DV+E P+F PS ++EV E
Sbjct: 396 LDFEAKNQHTLYVEVTN---EAPFVLKLPTSTATIV-VHVEDVNEAPVFVPPSKVVEVQE 451
Query: 395 NAKIGTVVGTVLAQDPDSTNSLVRYFINYNVEDDRFFNIDANTGTIRTTKVLDREETPW- 453
G V A+DPD N + Y I + + +D ++G + LDRE+ +
Sbjct: 452 GIPTGEPVCVYTAEDPDKENQKISYRILRDPAG--WLAMDPDSGQVTAVGTLDREDEQFV 509
Query: 454 ----YNITVTASEIDNPDLLSHVTVGIRVLDVNDNPPELAREYDIIVCENSKPGQVIHTI 509
Y + V A + +P T+ + ++DVND+ P + I +C S QV++
Sbjct: 510 RNNIYEVMVLAMDNGSPPTTGTGTLLLTLIDVNDHGP-VPEPRQITICNQSPVRQVLNI- 567
Query: 510 SATDKDDFANGPRFNFFLDERLPVNPNFTLKDNEDNTASILTRRRRFSRTVQDVYYLPIM 569
TDKD + F L + + +T + NE+ +L+ ++ QD Y + +
Sbjct: 568 --TDKDLSPHTSPFQAQLTDDSDIY--WTAEVNEEGDTVVLSLKKFLK---QDTYDVHLS 620
Query: 570 ISDGGIPSLSSSSTLTIRVCACERDGRVRTCHAEAFLSSAGLSTGALIAILLCVLILLAI 629
+SD G + IR C+ G V TC GA++A+L +L+LL
Sbjct: 621 LSDHG----NKEQLTVIRATVCDCHGHVETCPGPWKGGFILPVLGAVLALLFLLLVLL-- 674
Query: 630 VVLFITLRRSKKEPLIISEEDVRENVVTYDDEGGGEEDTEAFDITAL-RNPSAAEELKYR 688
L + +R KEPL++ E+D R+NV Y +EGGGEED + +DIT L R A E+ R
Sbjct: 675 --LLVRKKRKIKEPLLLPEDDTRDNVFYYGEEGGGEEDQD-YDITQLHRGLEARPEVVLR 731
Query: 689 RDIRPEVKLTPRHQTSSTLESIDVQEFIKQRLAEADLDPSVPPYDSLQTYAYEGQRSEAG 748
D+ P + TP ++ ++ FI + L A+ DP+ PPYD+L + YEG S+A
Sbjct: 732 NDVAPTIIPTPMYRPRPANPD-EIGNFIIENLKAANTDPTAPPYDTLLVFDYEGSGSDAA 790
Query: 749 SISSLDSATTQSDQDYHYLGDWGPEFKKLAELYGEIESE 787
S+SSL S+ + DQDY YL +WG FKKLA++YG E +
Sbjct: 791 SLSSLTSSASDQDQDYDYLNEWGSRFKKLADMYGGGEDD 829
>gi|13435361 desmocollin 1 isoform Dsc1a preproprotein [Homo
sapiens]
Length = 894
Score = 274 bits (700), Expect = 3e-73
Identities = 231/782 (29%), Positives = 373/782 (47%), Gaps = 75/782 (9%)
Query: 50 RPKRGWVWNQFFVLEEHMGPDPQYVGKLHSNSDKGDGSVKYILTGEGAG----TIFIIDD 105
R KR W ++E +GP PQ+V ++ S++ + + ++ Y ++G G +F I+
Sbjct: 131 RSKRRWAPIPASLMENSLGPFPQHVQQIQSDAAQ-NYTIFYSISGPGVDKEPFNLFYIEK 189
Query: 106 TTGDIHSTKSLDREQKTHYVLHAQAIDRRTNKPLEPESEFIIKVQDINDNAPKFTDGPYI 165
TGDI T+S+DRE+ + L+ A P P IIK++D NDNAP F I
Sbjct: 190 DTGDIFCTRSIDREKYEQFALYGYATTADGYAPEYP-LPLIIKIEDDNDNAPYFEHRVTI 248
Query: 166 VTVPEMSDMGTSVLQVTATDADDPTYGNSARVVYSILQGQP----YFSVDPKTGVIRTAL 221
TVPE GTSV +VTATD D+P ++ R+ Y ILQ P +FS+ P TGVI T
Sbjct: 249 FTVPENCRSGTSVGKVTATDLDEPDTLHT-RLKYKILQQIPDHPKHFSIHPDTGVITTTT 307
Query: 222 HNMDREAREHYSVVIQAKDMAGQVGGLSGSTTVNITLTDVNDNPPRFPQKHYQLYVPESA 281
+DRE + Y ++++ +DM GQ GL + T+ I+L D NDNPP F + Y V E+
Sbjct: 308 PFLDREKCDTYQLIMEVRDMGGQPFGLFNTGTITISLEDENDNPPSFTETSYVTEVEEN- 366
Query: 282 QVGSAVGKIKANDADTGS--NADMTYSIINGDGMGIFSISTDKETREGILSLKKPLNYEK 339
++ + ++K D D + ++ Y I+ G+ G F ISTD T EG+L + KPLNYE
Sbjct: 367 RIDVEILRMKVQDQDLPNTPHSKAVYKILQGNENGNFIISTDPNTNEGVLCVVKPLNYEV 426
Query: 340 KKSYTLNIEGAN-THLDFRFSHLGPFKDATMLKIIVGDVDEPPLFSMPSYLMEVYENAKI 398
+ L + N S P T + + + D DE P P +++ +
Sbjct: 427 NRQVILQVGVINEAQFSKAASSQTPTMCTTTVTVKIIDSDEGPECHPPVKVIQSQDGFPA 486
Query: 399 GTVVGTVLAQDPD-STNSLVRYFINYNVEDDRFFNIDANTGTIRTTKVLDRE----ETPW 453
G + A DP+ S+ +RY ++D +F I+ +TG +RT KVLDRE +
Sbjct: 487 GQELLGYKALDPEISSGEGLRY--QKLGDEDNWFEINQHTGDLRTLKVLDRESKFVKNNQ 544
Query: 454 YNITVTASEIDNPDLLSHVTVGIRVLDVNDNPPELAREYDIIVCENSKPGQVIHTISATD 513
YNI+V A +D T+ + + D ND+ P++ +E + +C+N++ V+ + D
Sbjct: 545 YNISVVA--VDAVGRSCTGTLVVHLDDYNDHAPQIDKE--VTICQNNEDFAVLKPV---D 597
Query: 514 KDDFANGPRFNFFLDERLPVNPNFTLKDNEDNTASILTRRRRFSRTVQDVYYLPIMISDG 573
D NGP F FFLD N N + +D +IL +R+ + Y +PI I D
Sbjct: 598 PDGPENGPPFQFFLDNSASKNWNI---EEKDGKTAILRQRQNLD---YNYYSVPIQIKDR 651
Query: 574 GIPSLSSSSTLTIRVCACE--RDGRVRTCHAEAFLSSAGLSTGALIAILLCVLILLAIVV 631
L ++ LT+RVC C + R++ + L A++A++L ++LL I+
Sbjct: 652 --HGLVATHMLTVRVCDCSTPSECRMKDKSTRDVRPNVILGRWAILAMVLGSVLLLCILF 709
Query: 632 LFITLRRSKKEPLIISEEDVRENVVTYDDEGGGEEDTEA-----------FDITALRNPS 680
+ + E+ ++N++ + EG GEE TEA D +
Sbjct: 710 TCFCVTAKRTVKKCFPEDIAQQNLIVSNTEGPGEEVTEANIRLPMQTSNICDTSMSVGTV 769
Query: 681 AAEELKYRRDIRP-------EVKLTPRHQTSSTLESI-----------DVQEFIKQRLAE 722
+ +K ++ + HQT +++ + D Q F + RL E
Sbjct: 770 GGQGIKTQQSFEMVKGGYTLDSNKGGGHQTLESVKGVGQGDTGRYAYTDWQSFTQPRLGE 829
Query: 723 -----ADLDPSVPPYDSLQTYAYEGQRSEAGSISSLDSATTQSDQDYHYLGDWGPEFKKL 777
+ D + +Y YEG+ S AGS+ + Q ++ +L P+F+ L
Sbjct: 830 KVYLCGQDEEHKHCEDYVCSYNYEGKGSLAGSVGC--CSDRQEEEGLEFLDHLEPKFRTL 887
Query: 778 AE 779
A+
Sbjct: 888 AK 889
>gi|4826702 desmocollin 1 isoform Dsc1b preproprotein [Homo sapiens]
Length = 840
Score = 270 bits (691), Expect = 3e-72
Identities = 205/639 (32%), Positives = 324/639 (50%), Gaps = 39/639 (6%)
Query: 50 RPKRGWVWNQFFVLEEHMGPDPQYVGKLHSNSDKGDGSVKYILTGEGAG----TIFIIDD 105
R KR W ++E +GP PQ+V ++ S++ + + ++ Y ++G G +F I+
Sbjct: 131 RSKRRWAPIPASLMENSLGPFPQHVQQIQSDAAQ-NYTIFYSISGPGVDKEPFNLFYIEK 189
Query: 106 TTGDIHSTKSLDREQKTHYVLHAQAIDRRTNKPLEPESEFIIKVQDINDNAPKFTDGPYI 165
TGDI T+S+DRE+ + L+ A P P IIK++D NDNAP F I
Sbjct: 190 DTGDIFCTRSIDREKYEQFALYGYATTADGYAPEYP-LPLIIKIEDDNDNAPYFEHRVTI 248
Query: 166 VTVPEMSDMGTSVLQVTATDADDPTYGNSARVVYSILQGQP----YFSVDPKTGVIRTAL 221
TVPE GTSV +VTATD D+P ++ R+ Y ILQ P +FS+ P TGVI T
Sbjct: 249 FTVPENCRSGTSVGKVTATDLDEPDTLHT-RLKYKILQQIPDHPKHFSIHPDTGVITTTT 307
Query: 222 HNMDREAREHYSVVIQAKDMAGQVGGLSGSTTVNITLTDVNDNPPRFPQKHYQLYVPESA 281
+DRE + Y ++++ +DM GQ GL + T+ I+L D NDNPP F + Y V E+
Sbjct: 308 PFLDREKCDTYQLIMEVRDMGGQPFGLFNTGTITISLEDENDNPPSFTETSYVTEVEEN- 366
Query: 282 QVGSAVGKIKANDADTGS--NADMTYSIINGDGMGIFSISTDKETREGILSLKKPLNYEK 339
++ + ++K D D + ++ Y I+ G+ G F ISTD T EG+L + KPLNYE
Sbjct: 367 RIDVEILRMKVQDQDLPNTPHSKAVYKILQGNENGNFIISTDPNTNEGVLCVVKPLNYEV 426
Query: 340 KKSYTLNIEGAN-THLDFRFSHLGPFKDATMLKIIVGDVDEPPLFSMPSYLMEVYENAKI 398
+ L + N S P T + + + D DE P P +++ +
Sbjct: 427 NRQVILQVGVINEAQFSKAASSQTPTMCTTTVTVKIIDSDEGPECHPPVKVIQSQDGFPA 486
Query: 399 GTVVGTVLAQDPD-STNSLVRYFINYNVEDDRFFNIDANTGTIRTTKVLDRE----ETPW 453
G + A DP+ S+ +RY ++D +F I+ +TG +RT KVLDRE +
Sbjct: 487 GQELLGYKALDPEISSGEGLRY--QKLGDEDNWFEINQHTGDLRTLKVLDRESKFVKNNQ 544
Query: 454 YNITVTASEIDNPDLLSHVTVGIRVLDVNDNPPELAREYDIIVCENSKPGQVIHTISATD 513
YNI+V A +D T+ + + D ND+ P++ +E + +C+N++ V+ + D
Sbjct: 545 YNISVVA--VDAVGRSCTGTLVVHLDDYNDHAPQIDKE--VTICQNNEDFAVLKPV---D 597
Query: 514 KDDFANGPRFNFFLDERLPVNPNFTLKDNEDNTASILTRRRRFSRTVQDVYYLPIMISDG 573
D NGP F FFLD N N + +D +IL +R+ + Y +PI I D
Sbjct: 598 PDGPENGPPFQFFLDNSASKNWNI---EEKDGKTAILRQRQNLD---YNYYSVPIQIKDR 651
Query: 574 GIPSLSSSSTLTIRVCACE--RDGRVRTCHAEAFLSSAGLSTGALIAILLCVLILLAIVV 631
L ++ LT+RVC C + R++ + L A++A++L ++LL I+
Sbjct: 652 --HGLVATHMLTVRVCDCSTPSECRMKDKSTRDVRPNVILGRWAILAMVLGSVLLLCILF 709
Query: 632 LFITLRRSKKEPLIISEEDVRENVVTYDDEGGGEEDTEA 670
+ + E+ ++N++ + EG GEE TEA
Sbjct: 710 TCFCVTAKRTVKKCFPEDIAQQNLIVSNTEGPGEEVTEA 748
>gi|148539846 desmocollin 3 isoform Dsc3a preproprotein [Homo
sapiens]
Length = 896
Score = 269 bits (687), Expect = 9e-72
Identities = 238/798 (29%), Positives = 379/798 (47%), Gaps = 80/798 (10%)
Query: 36 NQTKHIEGETEVHHRPKRGWVWNQFFVLEEHMGPDPQYVGKLHSNSDKGDGSVKYILTGE 95
++T+H ET V R KR W + E +GP P ++ ++ S++ + + +V Y ++G
Sbjct: 120 SKTRHTR-ET-VLRRAKRRWAPIPCSMQENSLGPFPLFLQQVESDAAQ-NYTVFYSISGR 176
Query: 96 GAG----TIFIIDDTTGDIHSTKSLDREQKTHYVLHAQAIDRRTNKPLEPESEFIIKVQD 151
G +F I+ TG++ T+ +DRE+ + L A A + I+V+D
Sbjct: 177 GVDKEPLNLFYIERDTGNLFCTRPVDREEYDVFDLIAYA-STADGYSADLPLPLPIRVED 235
Query: 152 INDNAPKFTDGPYIVTVPEMSDMGTSVLQVTATDADDPTYGNSARVVYSILQGQP----Y 207
NDN P FT+ Y V E S GT+V V ATD D+P ++ R+ YSILQ P
Sbjct: 236 ENDNHPVFTEAIYNFEVLESSRPGTTVGVVCATDRDEPDTMHT-RLKYSILQQTPRSPGL 294
Query: 208 FSVDPKTGVIRTALHNMDREAREHYSVVIQAKDMAGQVGGLSGSTTVNITLTDVNDNPPR 267
FSV P TGVI T H +DRE + YS++++ +DM GQ GL G++T IT+TD NDN P
Sbjct: 295 FSVHPSTGVITTVSHYLDREVVDKYSLIMKVQDMDGQFFGLIGTSTCIITVTDSNDNAPT 354
Query: 268 FPQKHYQLYVPESAQVGSAVGKIKANDADTGSNAD--MTYSIINGDGMGIFSISTDKETR 325
F Q Y+ +V E+A + +I D D + A+ + ++I+ G+ G F ISTDKET
Sbjct: 355 FRQNAYEAFVEENA-FNVEILRIPIEDKDLINTANWRVNFTILKGNENGHFKISTDKETN 413
Query: 326 EGILSLKKPLNYEKKKSYTLNIEGANTHLDF-RFSHLGPFKDATMLKIIVGDVDEPPLFS 384
EG+LS+ KPLNYE+ + L I G N F R + ++ + V D+DE P +
Sbjct: 414 EGVLSVVKPLNYEENRQVNLEI-GVNNEAPFARDIPRVTALNRALVTVHVRDLDEGPECT 472
Query: 385 MPSYLMEVYENAKIGTVVGTVLAQDPDSTN-SLVRYFINYNVEDDR-FFNIDANTGTIRT 442
+ + + EN +G+ + A DP++ N + +RY + D + + ID +G+I T
Sbjct: 473 PAAQYVRIKENLAVGSKINGYKAYDPENRNGNGLRY---KKLHDPKGWITIDEISGSIIT 529
Query: 443 TKVLDRE-ETP---WYNITVTASEIDNPDLLSHVTVGIRVLDVNDNPPELAREYDIIVCE 498
+K+LDRE ETP YNITV A ID D T+ + + DVNDNPPE+ +EY +++C
Sbjct: 530 SKILDREVETPKNELYNITVLA--IDKDDRSCTGTLAVNIEDVNDNPPEILQEY-VVIC- 585
Query: 499 NSKPGQVIHTISATDKDDFANGPRFNFFLDERLPVNPNFTLKDNEDNTASILTRRRRFSR 558
KP I A D D+ +G F F L P ++TA+ L+ ++
Sbjct: 586 --KPKMGYTDILAVDPDEPVHGAPFYFSLPNTSPEISRLWSLTKVNDTAARLSYQKNAG- 642
Query: 559 TVQDVYYLPIMISDGGIPSLSSSSTLTIRVCACERDGRVRTCHAEAFLSSAGLSTGALIA 618
Y +PI + D +++ L + +C C + C A + + L A++A
Sbjct: 643 --FQEYTIPITVKDRA--GQAATKLLRVNLCECTHPTQ---CRATSRSTGVILGKWAILA 695
Query: 619 ILLCVLILLAIVVLFITLRRSKKEPLIISEEDVRENVVTYDDEGGGEE---DTEAFDITA 675
ILL + +L ++++ + + E+ ++N++ + E G++ F
Sbjct: 696 ILLGIALLFSVLLTLVCGVFGATKGKRFPEDLAQQNLIISNTEAPGDDRVCSANGFMTQT 755
Query: 676 LRNPS-----------------AAEELKYRRDIRPEVKLTPRHQTSSTLES--------- 709
N S E +K + H T +
Sbjct: 756 TNNSSQGFCGTMGSGMKNGGQETIEMMKGGNQTLESCRGAGHHHTLDSCRGGHTEVDNCR 815
Query: 710 ---IDVQEFIKQRLAEA-----DLDPSVPPYDSLQTYAYEGQRSEAGSISSLDSATTQSD 761
+ F + RL E + +P D + TY YEG+ S AGS+ + Q +
Sbjct: 816 YTYSEWHSFTQPRLGEKLHRCNQNEDRMPSQDYVLTYNYEGRGSPAGSVGC--CSEKQEE 873
Query: 762 QDYHYLGDWGPEFKKLAE 779
+L + P+F LAE
Sbjct: 874 DGLDFLNNLEPKFITLAE 891
>gi|148539848 desmocollin 3 isoform Dsc3b preproprotein [Homo
sapiens]
Length = 839
Score = 262 bits (670), Expect = 8e-70
Identities = 209/648 (32%), Positives = 335/648 (51%), Gaps = 41/648 (6%)
Query: 36 NQTKHIEGETEVHHRPKRGWVWNQFFVLEEHMGPDPQYVGKLHSNSDKGDGSVKYILTGE 95
++T+H ET V R KR W + E +GP P ++ ++ S++ + + +V Y ++G
Sbjct: 120 SKTRHTR-ET-VLRRAKRRWAPIPCSMQENSLGPFPLFLQQVESDAAQ-NYTVFYSISGR 176
Query: 96 GAG----TIFIIDDTTGDIHSTKSLDREQKTHYVLHAQAIDRRTNKPLEPESEFIIKVQD 151
G +F I+ TG++ T+ +DRE+ + L A A + I+V+D
Sbjct: 177 GVDKEPLNLFYIERDTGNLFCTRPVDREEYDVFDLIAYA-STADGYSADLPLPLPIRVED 235
Query: 152 INDNAPKFTDGPYIVTVPEMSDMGTSVLQVTATDADDPTYGNSARVVYSILQGQP----Y 207
NDN P FT+ Y V E S GT+V V ATD D+P ++ R+ YSILQ P
Sbjct: 236 ENDNHPVFTEAIYNFEVLESSRPGTTVGVVCATDRDEPDTMHT-RLKYSILQQTPRSPGL 294
Query: 208 FSVDPKTGVIRTALHNMDREAREHYSVVIQAKDMAGQVGGLSGSTTVNITLTDVNDNPPR 267
FSV P TGVI T H +DRE + YS++++ +DM GQ GL G++T IT+TD NDN P
Sbjct: 295 FSVHPSTGVITTVSHYLDREVVDKYSLIMKVQDMDGQFFGLIGTSTCIITVTDSNDNAPT 354
Query: 268 FPQKHYQLYVPESAQVGSAVGKIKANDADTGSNAD--MTYSIINGDGMGIFSISTDKETR 325
F Q Y+ +V E+A + +I D D + A+ + ++I+ G+ G F ISTDKET
Sbjct: 355 FRQNAYEAFVEENA-FNVEILRIPIEDKDLINTANWRVNFTILKGNENGHFKISTDKETN 413
Query: 326 EGILSLKKPLNYEKKKSYTLNIEGANTHLDF-RFSHLGPFKDATMLKIIVGDVDEPPLFS 384
EG+LS+ KPLNYE+ + L I G N F R + ++ + V D+DE P +
Sbjct: 414 EGVLSVVKPLNYEENRQVNLEI-GVNNEAPFARDIPRVTALNRALVTVHVRDLDEGPECT 472
Query: 385 MPSYLMEVYENAKIGTVVGTVLAQDPDSTN-SLVRYFINYNVEDDR-FFNIDANTGTIRT 442
+ + + EN +G+ + A DP++ N + +RY + D + + ID +G+I T
Sbjct: 473 PAAQYVRIKENLAVGSKINGYKAYDPENRNGNGLRY---KKLHDPKGWITIDEISGSIIT 529
Query: 443 TKVLDRE-ETP---WYNITVTASEIDNPDLLSHVTVGIRVLDVNDNPPELAREYDIIVCE 498
+K+LDRE ETP YNITV A ID D T+ + + DVNDNPPE+ +EY +++C
Sbjct: 530 SKILDREVETPKNELYNITVLA--IDKDDRSCTGTLAVNIEDVNDNPPEILQEY-VVIC- 585
Query: 499 NSKPGQVIHTISATDKDDFANGPRFNFFLDERLPVNPNFTLKDNEDNTASILTRRRRFSR 558
KP I A D D+ +G F F L P ++TA+ L+ ++
Sbjct: 586 --KPKMGYTDILAVDPDEPVHGAPFYFSLPNTSPEISRLWSLTKVNDTAARLSYQKNAG- 642
Query: 559 TVQDVYYLPIMISDGGIPSLSSSSTLTIRVCACERDGRVRTCHAEAFLSSAGLSTGALIA 618
Y +PI + D +++ L + +C C + C A + + L A++A
Sbjct: 643 --FQEYTIPITVKDRA--GQAATKLLRVNLCECTHPTQ---CRATSRSTGVILGKWAILA 695
Query: 619 ILLCVLILLAIVVLFITLRRSKKEPLIISEEDVRENVVTYDDEGGGEE 666
ILL + +L ++++ + + E+ ++N++ + E G++
Sbjct: 696 ILLGIALLFSVLLTLVCGVFGATKGKRFPEDLAQQNLIISNTEAPGDD 743
>gi|13435364 desmocollin 2 isoform Dsc2a preproprotein [Homo
sapiens]
Length = 901
Score = 247 bits (630), Expect = 3e-65
Identities = 233/806 (28%), Positives = 381/806 (47%), Gaps = 82/806 (10%)
Query: 34 MRNQTKHIEG---ETEVHHRPKRGWVWNQFFVLEEHMGPDPQYVGKLHSNSDKGDGSVKY 90
+ +QTK ++ + +V R KR W +LE +GP P ++ ++ S++ + + ++ Y
Sbjct: 113 LEHQTKVLKKRHTKEKVLRRAKRRWAPIPCSMLENSLGPFPLFLQQVQSDTAQ-NYTIYY 171
Query: 91 ILTGEGAG----TIFIIDDTTGDIHSTKSLDREQKTHYVLHAQAIDRRTNKPLEPESEFI 146
+ G G +F ++ TG+++ T+ +DREQ + + A A P P I
Sbjct: 172 SIRGPGVDQEPRNLFYVERDTGNLYCTRPVDREQYESFEIIAFATTPDGYTPELP-LPLI 230
Query: 147 IKVQDINDNAPKFTDGPYIVTVPEMSDMGTSVLQVTATDADDPTYGNSARVVYSILQGQP 206
IK++D NDN P FT+ Y T+ E +GT+V QV ATD D+P ++ R+ YSI+ P
Sbjct: 231 IKIEDENDNYPIFTEETYTFTIFENCRVGTTVGQVCATDKDEPDTMHT-RLKYSIIGQVP 289
Query: 207 ----YFSVDPKTGVIRTALHNMDREAREHYSVVIQAKDMAGQVGGLSGSTTVNITLTDVN 262
FS+ P TGVI T +DRE + Y + I+ +DM GQ GL ++T I + DVN
Sbjct: 290 PSPTLFSMHPTTGVITTTSSQLDRELIDKYQLKIKVQDMDGQYFGLQTTSTCIINIDDVN 349
Query: 263 DNPPRFPQKHYQLYVPESAQVGSAVGKIKANDADTGSNAD--MTYSIINGDGMGIFSIST 320
D+ P F + Y V E+ V + ++ D D + A+ Y+I+ G+ G F I T
Sbjct: 350 DHLPTFTRTSYVTSVEENT-VDVEILRVTVEDKDLVNTANWRANYTILKGNENGNFKIVT 408
Query: 321 DKETREGILSLKKPLNYEKKKSYTLNIEGANTHLDFRFSHLGPFKDATMLKIIVGDVDEP 380
D +T EG+L + KPLNYE+K+ L I N R + + + V D DE
Sbjct: 409 DAKTNEGVLCVVKPLNYEEKQQMILQIGVVNEAPFSREASPRSAMSTATVTVNVEDQDEG 468
Query: 381 PLFSMPSYLMEVYENAKIGTVVGTVLAQDPDS-TNSLVRYFINYNVEDDRFFNIDANTGT 439
P + P + + ENA++GT A DP++ ++S +RY + + ID NTG+
Sbjct: 469 PECNPPIQTVRMKENAEVGTTSNGYKAYDPETRSSSGIRY--KKLTDPTGWVTIDENTGS 526
Query: 440 IRTTKVLDRE----ETPWYNITVTASEIDNPDLLSHVTVGIRVLDVNDNPPELAREYDII 495
I+ + LDRE + YNITV AS D T+GI + DVNDN P + ++ +I
Sbjct: 527 IKVFRSLDREAETIKNGIYNITVLAS--DQGGRTCTGTLGIILQDVNDNSPFIPKK-TVI 583
Query: 496 VCENSKPGQVIHTISATDKDDFANGPRFNFFLDERL-PVNPNFTLKDNEDNTASILTRRR 554
+C KP I A D D+ +GP F+F L+ V + LK D A + +
Sbjct: 584 IC---KPTMSSAEIVAVDPDEPIHGPPFDFSLESSTSEVQRMWRLKAINDTAARLSYQ-- 638
Query: 555 RFSRTVQDVYYLPIMISDGGIPSLSSSSTLTIRVCACERDGRVRTCHAEAFLSSAGLSTG 614
+ Y +PI + D +SS ++L + +C C + T + + G+ G
Sbjct: 639 --NDPPFGSYVVPITVRDR--LGMSSVTSLDVTLCDCITENDC-THRVDPRIGGGGVQLG 693
Query: 615 --ALIAILLCVLILLAIV-VLFITLRRSKKEPLIISEEDVRENVVTYDDEGGGEEDTEAF 671
A++AILL + +L I+ L + K+P +I ++ ++N++ + E G++ +
Sbjct: 694 KWAILAILLGIALLFCILFTLVCGASGTSKQPKVIPDDLAQQNLIVSNTEAPGDDKVYSA 753
Query: 672 DITALRNPSAAEE---------LKYRRDIRPEVKLTPRHQTSS---------TLESI--- 710
+ + A+ + +K E+ + HQTS TL+S
Sbjct: 754 NGFTTQTVGASAQGVCGTVGSGIKNGGQETIEM-VKGGHQTSESCRGAGHHHTLDSCRGG 812
Query: 711 ------------DVQEFIKQRLAEA-----DLDPSVPPYDSLQTYAYEGQRSEAGSISSL 753
+ F + RL E + D + TY YEG+ S AGS+
Sbjct: 813 HTEVDNCRYTYSEWHSFTQPRLGEKVYLCNQDENHKHAQDYVLTYNYEGRGSVAGSVGC- 871
Query: 754 DSATTQSDQDYHYLGDWGPEFKKLAE 779
+ Q + +L + P+F+ LAE
Sbjct: 872 -CSERQEEDGLEFLDNLEPKFRTLAE 896
>gi|4502719 cadherin 13 preproprotein [Homo sapiens]
Length = 713
Score = 245 bits (625), Expect = 1e-64
Identities = 210/602 (34%), Positives = 314/602 (52%), Gaps = 48/602 (7%)
Query: 50 RPKRGWVWNQFFVLEEHMGPDPQYVGKLHSNSDKGDGSVKYILTGEGAGT----IFIIDD 105
R KR V + + E P P+ VGK+ +SD+ + S K+ LTG+G IF I++
Sbjct: 135 RQKRSIVVSPILIPENQRQPFPRDVGKV-VDSDRPERS-KFRLTGKGVDQEPKGIFRINE 192
Query: 106 TTGDIHSTKSLDREQKTHYVLHAQAIDRRTNKPLEPESEFIIKVQDINDNAPKFTDGPYI 165
TG + T++LDRE Y L + D K LE + V D NDN P F +GPYI
Sbjct: 193 NTGSVSVTRTLDREVIAVYQLFVETTDVN-GKTLEGPVPLEVIVIDQNDNRPIFREGPYI 251
Query: 166 VTVPEMSDMGTSVLQVTATDADDPTYGNSARVVYSILQGQP------YFSVDPKTGVIRT 219
V E S GT+V+++TA DADDP N A + Y+I Q P F +DP+ G I T
Sbjct: 252 GHVMEGSPTGTTVMRMTAFDADDPATDN-ALLRYNIRQQTPDKPSPNMFYIDPEKGDIVT 310
Query: 220 ALHN--MDREAREH--YSVVIQAKDMAGQVGGLSGSTTVNITLTDVNDNPPRFPQKHYQL 275
+ +DRE E+ Y ++I+A+DMAG GL+G+ T I + D ND+ P+F +K +Q
Sbjct: 311 VVSPALLDRETLENPKYELIIEAQDMAGLDVGLTGTATATIMIDDKNDHSPKFTKKEFQA 370
Query: 276 YVPESAQVGSAVG-KIKANDADTGSNADMTYSIINGDGMGIFSISTDKETREGILSLKKP 334
V E A VG V ++ D T Y+IING+ F I T+ +T EG+LS+ KP
Sbjct: 371 TVEEGA-VGVIVNLTVEDKDDPTTGAWRAAYTIINGNPGQSFEIHTNPQTNEGMLSVVKP 429
Query: 335 LNYEKKKSYTLNIEGANTHLDFRFSHLGPFKDATMLKIIVGDVDEPPLFSMPSYLMEVYE 394
L+YE +TL I+ N GP AT + I V DV+E P+F ++ E
Sbjct: 430 LDYEISAFHTLLIKVENEDPLVPDVSYGPSSTAT-VHITVLDVNEGPVFYPDPMMVTRQE 488
Query: 395 NAKIGTVVGTVLAQDPDSTNSLVRYFINYNVEDD--RFFNIDANTGTIRTTKVLDRE--- 449
+ +G+V+ TV A DPD SL I Y+V D + NI+ GT+ TT VLDRE
Sbjct: 489 DLSVGSVLLTVNATDPD---SLQHQTIRYSVYKDPAGWLNINPINGTVDTTAVLDRESPF 545
Query: 450 -ETPWYNITVTASEIDNPDLLSHVTVGIRVLDVNDNPPELAREYDII--VCENSKPGQVI 506
+ Y A + NP T+ I + DVNDN P + Y + VC+++K V+
Sbjct: 546 VDNSVYTALFLAIDSGNPPATGTGTLLITLEDVNDNAPFI---YPTVAEVCDDAKNLSVV 602
Query: 507 HTISATDKDDFANGPRFNFFLDERLPVNPNFTLKDNEDNTASILTRRRRFSRTVQDVYYL 566
+ A+DKD N F F + ++ + + + +NT ++++ + ++ Y L
Sbjct: 603 -ILGASDKDLHPNTDPFKFEIHKQAVPDKVWKI-SKINNTHALVSLLQNLNKA---NYNL 657
Query: 567 PIMISDGGIPSLSSSSTLTIRVCACERDGRVRTCHAEAFLSSAGLSTGALIAILLCVLIL 626
PIM++D G P +++ + L ++VC+C R+ +V C+A AG +L ++LL L
Sbjct: 658 PIMVTDSGKPPMTNITDLRVQVCSC-RNSKV-DCNA------AGALRFSLPSVLLLSLFS 709
Query: 627 LA 628
LA
Sbjct: 710 LA 711
>gi|13435366 desmocollin 2 isoform Dsc2b preproprotein [Homo
sapiens]
Length = 847
Score = 244 bits (622), Expect = 3e-64
Identities = 202/655 (30%), Positives = 329/655 (50%), Gaps = 41/655 (6%)
Query: 34 MRNQTKHIEG---ETEVHHRPKRGWVWNQFFVLEEHMGPDPQYVGKLHSNSDKGDGSVKY 90
+ +QTK ++ + +V R KR W +LE +GP P ++ ++ S++ + + ++ Y
Sbjct: 113 LEHQTKVLKKRHTKEKVLRRAKRRWAPIPCSMLENSLGPFPLFLQQVQSDTAQ-NYTIYY 171
Query: 91 ILTGEGAG----TIFIIDDTTGDIHSTKSLDREQKTHYVLHAQAIDRRTNKPLEPESEFI 146
+ G G +F ++ TG+++ T+ +DREQ + + A A P P I
Sbjct: 172 SIRGPGVDQEPRNLFYVERDTGNLYCTRPVDREQYESFEIIAFATTPDGYTPELP-LPLI 230
Query: 147 IKVQDINDNAPKFTDGPYIVTVPEMSDMGTSVLQVTATDADDPTYGNSARVVYSILQGQP 206
IK++D NDN P FT+ Y T+ E +GT+V QV ATD D+P ++ R+ YSI+ P
Sbjct: 231 IKIEDENDNYPIFTEETYTFTIFENCRVGTTVGQVCATDKDEPDTMHT-RLKYSIIGQVP 289
Query: 207 ----YFSVDPKTGVIRTALHNMDREAREHYSVVIQAKDMAGQVGGLSGSTTVNITLTDVN 262
FS+ P TGVI T +DRE + Y + I+ +DM GQ GL ++T I + DVN
Sbjct: 290 PSPTLFSMHPTTGVITTTSSQLDRELIDKYQLKIKVQDMDGQYFGLQTTSTCIINIDDVN 349
Query: 263 DNPPRFPQKHYQLYVPESAQVGSAVGKIKANDADTGSNAD--MTYSIINGDGMGIFSIST 320
D+ P F + Y V E+ V + ++ D D + A+ Y+I+ G+ G F I T
Sbjct: 350 DHLPTFTRTSYVTSVEENT-VDVEILRVTVEDKDLVNTANWRANYTILKGNENGNFKIVT 408
Query: 321 DKETREGILSLKKPLNYEKKKSYTLNIEGANTHLDFRFSHLGPFKDATMLKIIVGDVDEP 380
D +T EG+L + KPLNYE+K+ L I N R + + + V D DE
Sbjct: 409 DAKTNEGVLCVVKPLNYEEKQQMILQIGVVNEAPFSREASPRSAMSTATVTVNVEDQDEG 468
Query: 381 PLFSMPSYLMEVYENAKIGTVVGTVLAQDPDS-TNSLVRYFINYNVEDDRFFNIDANTGT 439
P + P + + ENA++GT A DP++ ++S +RY + + ID NTG+
Sbjct: 469 PECNPPIQTVRMKENAEVGTTSNGYKAYDPETRSSSGIRY--KKLTDPTGWVTIDENTGS 526
Query: 440 IRTTKVLDRE----ETPWYNITVTASEIDNPDLLSHVTVGIRVLDVNDNPPELAREYDII 495
I+ + LDRE + YNITV AS D T+GI + DVNDN P + ++ +I
Sbjct: 527 IKVFRSLDREAETIKNGIYNITVLAS--DQGGRTCTGTLGIILQDVNDNSPFIPKK-TVI 583
Query: 496 VCENSKPGQVIHTISATDKDDFANGPRFNFFLDERL-PVNPNFTLKDNEDNTASILTRRR 554
+C KP I A D D+ +GP F+F L+ V + LK D A + +
Sbjct: 584 IC---KPTMSSAEIVAVDPDEPIHGPPFDFSLESSTSEVQRMWRLKAINDTAARLSYQ-- 638
Query: 555 RFSRTVQDVYYLPIMISDGGIPSLSSSSTLTIRVCACERDGRVRTCHAEAFLSSAGLSTG 614
+ Y +PI + D +SS ++L + +C C + T + + G+ G
Sbjct: 639 --NDPPFGSYVVPITVRDR--LGMSSVTSLDVTLCDCITENDC-THRVDPRIGGGGVQLG 693
Query: 615 --ALIAILLCVLILLAIV-VLFITLRRSKKEPLIISEEDVRENVVTYDDEGGGEE 666
A++AILL + +L I+ L + K+P +I ++ ++N++ + E G++
Sbjct: 694 KWAILAILLGIALLFCILFTLVCGASGTSKQPKVIPDDLAQQNLIVSNTEAPGDD 748
>gi|66346693 FAT tumor suppressor 1 precursor [Homo sapiens]
Length = 4588
Score = 232 bits (591), Expect = 1e-60
Identities = 166/510 (32%), Positives = 267/510 (52%), Gaps = 31/510 (6%)
Query: 83 KGDGSVKYILTGEGAGTIFIIDDTTGDIHSTKSLDREQKTHYVLHAQAIDRRTNKPLEPE 142
+ + + Y L G GA F ++ TG++ ++ LDRE++ Y L +A D +
Sbjct: 3053 RSNAEITYTLLGSGAEK-FKLNPDTGELKTSTPLDREEQAVYHLLVRATDGGGRFC---Q 3108
Query: 143 SEFIIKVQDINDNAPKFTDGPYIVTVPEMSDMGTSVLQVTATDADDPTYGNSARVVYSIL 202
+ ++ ++D+NDNAP+F+ PY +TV E ++ GT + +V ATDAD G + +++YS++
Sbjct: 3109 ASIVLTLEDVNDNAPEFSADPYAITVFENTEPGTLLTRVQATDADA---GLNRKILYSLI 3165
Query: 203 QGQP-YFSVDPKTGVIRTALHNMDREAREHYSVVIQAKDMAGQVGGLSGSTTVNITLTDV 261
FS++ +G+I+ +DRE + Y++ ++A D G L+ + TV +++ D+
Sbjct: 3166 DSADGQFSINELSGIIQLE-KPLDRELQAVYTLSLKAVDQ-GLPRRLTATGTVIVSVLDI 3223
Query: 262 NDNPPRFPQKHYQLYVPESAQVGSAVGKIKANDADTGSNADMTYSIINGDGMGIFSISTD 321
NDNPP F + Y V E VG+ V ++ A D +NA++TYSII+G+ G FSI
Sbjct: 3224 NDNPPVFEYREYGATVSEDILVGTEVLQVYAASRDIEANAEITYSIISGNEHGKFSI--- 3280
Query: 322 KETREGILSLKKPLNYEKKKSYTLNIEGANTHLDFRFSHLGPFKDATMLKIIVGDV-DEP 380
+++ G + + + L+YE Y L +E + D + + V D+ D
Sbjct: 3281 -DSKTGAVFIIENLDYESSHEYYLTVEATD-------GGTPSLSDVATVNVNVTDINDNT 3332
Query: 381 PLFSMPSYLMEVYENAKIGTVVGTVLAQDPDS-TNSLVRYFINYNVEDDRFFNIDANTGT 439
P+FS +Y + E+A + V TV+A D D +NS + Y I + F ID G
Sbjct: 3333 PVFSQDTYTTVISEDAVLEQSVITVMADDADGPSNSHIHYSI-IDGNQGSSFTIDPVRGE 3391
Query: 440 IRTTKVLDREETPWYNITVTASEIDNPDLLSHVTVGIRVLDVNDNPPELAR-EYDIIVCE 498
++ TK+LDRE Y +TV AS+ +P ++ TV I V DVNDN P +R Y +I+ E
Sbjct: 3392 VKVTKLLDRETISGYTLTVQASDNGSPPRVNTTTVNIDVSDVNDNAPVFSRGNYSVIIQE 3451
Query: 499 NSKPGQVIHTISATDKDDFANGPRFNFFLDERLPVNPNFTLKDNEDNTASILTRRRRFSR 558
N G + + TD+D NGP F F + V N K E N +L R
Sbjct: 3452 NKPVGFSVLQLVVTDEDSSHNGPPFFFTI-----VTGN-DEKAFEVNPQGVLLTSSAIKR 3505
Query: 559 TVQDVYYLPIMISDGGIPSLSSSSTLTIRV 588
+D Y L + ++D G P LSS + + IRV
Sbjct: 3506 KEKDHYLLQVKVADNGKPQLSSLTYIDIRV 3535
Score = 198 bits (503), Expect = 2e-50
Identities = 155/513 (30%), Positives = 247/513 (48%), Gaps = 35/513 (6%)
Query: 85 DGSVKYILTGEGAGTIFIIDDTTGDIHSTKSLDREQKTHYVLHAQAIDRRTNKPLEPESE 144
+G + Y ++G + F+ID TG + LDRE Y L+ D +
Sbjct: 749 NGKLVYAVSGGNEDSCFMIDMETGMLKILSPLDRETTDKYTLNITVYDLGIPQKAAWRLL 808
Query: 145 FIIKVQDINDNAPKFTDGPYIVTVPEMSDMGTSVLQVTATDADDPTYGNSARVVYSILQG 204
++ V D NDN P+F Y V V E ++ + ++QV ATD D G + V YSI+
Sbjct: 809 HVVVV-DANDNPPEFLQESYFVEVSEDKEVHSEIIQVEATDKD---LGPNGHVTYSIVTD 864
Query: 205 QPYFSVDPKTGVIRTALHNMDREAREHYSVVIQAKDMAGQVGGLSGSTTVNITLTDVNDN 264
FS+D TGV+ A +DRE + +S+ I+A+D A + L + V ++L DVNDN
Sbjct: 865 TDTFSIDSVTGVVNIA-RPLDRELQHEHSLKIEARDQAREEPQLFSTVVVKVSLEDVNDN 923
Query: 265 PPRFPQKHYQLYVPESAQVGSAVGKIKANDADTGSNADMTYSIINGDGMGIFSISTDKET 324
PP F +Y++ V E G+ + ++A+D D G + + YS+++ G G F D +
Sbjct: 924 PPTFIPPNYRVKVREDLPEGTVIMWLEAHDPDLGQSGQVRYSLLD-HGEGNF----DVDK 978
Query: 325 REGILSLKKPLNYEKKKSYTLNIEGANTHLDFRFSHLGPFKDATMLKIIVGDVDE---PP 381
G + + + L++EKK+ Y L + + S +++ V DV+E PP
Sbjct: 979 LSGAVRIVQQLDFEKKQVYNLTVRAKDKGKPVSLS------STCYVEVEVVDVNENLHPP 1032
Query: 382 LFSMPSYLMEVYENAKIGTVVGTVLAQDPDSTNSLVRYFINYNVEDDR---FFNIDANTG 438
+FS V E+A +G++V TV A D D+ I Y++ D F I TG
Sbjct: 1033 VFSSFVEKGTVKEDAPVGSLVMTVSAHDEDARRD---GEIRYSIRDGSGVGVFKIGEETG 1089
Query: 439 TIRTTKVLDREETPWYNITVTASEIDNPDLLSHVTVGIRVLDVNDNPPELARE-YDIIVC 497
I T+ LDRE T Y +TV A++ L S + + I V DVNDN P+ + Y +
Sbjct: 1090 VIETSDRLDRESTSHYWLTVFATDQGVVPLSSFIEIYIEVEDVNDNAPQTSEPVYYPEIM 1149
Query: 498 ENSKPGQVIHTISATDKDDFANGPRFNFFLDERLPVNPN--FTLKDNEDNTASILTRRRR 555
ENS + I A D D +N + + + NP F++ T I T R+
Sbjct: 1150 ENSPKDVSVVQIEAFDPDSSSN----DKLMYKITSGNPQGFFSI---HPKTGLITTTSRK 1202
Query: 556 FSRTVQDVYYLPIMISDGGIPSLSSSSTLTIRV 588
R QD + L + ++D G P S+ + + +++
Sbjct: 1203 LDREQQDEHILEVTVTDNGSPPKSTIARVIVKI 1235
Score = 180 bits (456), Expect = 5e-45
Identities = 136/420 (32%), Positives = 208/420 (49%), Gaps = 23/420 (5%)
Query: 101 FIIDDTTGDIHSTKSLDREQKTHYVLHAQAIDRRTNKPLEPESEFIIKVQDINDNAPKFT 160
F I++ +G I K LDRE + Y L +A+D+ + L I+ V DINDN P F
Sbjct: 3172 FSINELSGIIQLEKPLDRELQAVYTLSLKAVDQGLPRRLTATGTVIVSVLDINDNPPVFE 3231
Query: 161 DGPYIVTVPEMSDMGTSVLQVTATDADDPTYGNSARVVYSILQGQPY--FSVDPKTGVIR 218
Y TV E +GT VLQV A D +A + YSI+ G + FS+D KTG +
Sbjct: 3232 YREYGATVSEDILVGTEVLQVYAASRDIEA---NAEITYSIISGNEHGKFSIDSKTGAV- 3287
Query: 219 TALHNMDREAREHYSVVIQAKDMAGQVGGLSGSTTVNITLTDVNDNPPRFPQKHYQLYVP 278
+ N+D E+ Y + ++A D G LS TVN+ +TD+NDN P F Q Y +
Sbjct: 3288 FIIENLDYESSHEYYLTVEATD--GGTPSLSDVATVNVNVTDINDNTPVFSQDTYTTVIS 3345
Query: 279 ESAQVGSAVGKIKANDADTGSNADMTYSIINGDGMGIFSISTDKETREGILSLKKPLNYE 338
E A + +V + A+DAD SN+ + YSII+G+ F+I + G + + K L+ E
Sbjct: 3346 EDAVLEQSVITVMADDADGPSNSHIHYSIIDGNQGSSFTIDPVR----GEVKVTKLLDRE 3401
Query: 339 KKKSYTLNIEGANTHLDFRFSHLGPFKDATMLKIIVGDV-DEPPLFSMPSYLMEVYENAK 397
YTL ++ ++ P + T + I V DV D P+FS +Y + + EN
Sbjct: 3402 TISGYTLTVQASDNGSP-------PRVNTTTVNIDVSDVNDNAPVFSRGNYSVIIQENKP 3454
Query: 398 IGTVVGTVLAQDPDSTNSLVRYFINYNV-EDDRFFNIDANTGTIRTTKVLDREETPWYNI 456
+G V ++ D DS+++ +F D++ F ++ G + T+ + R+E Y +
Sbjct: 3455 VGFSVLQLVVTDEDSSHNGPPFFFTIVTGNDEKAFEVNPQ-GVLLTSSAIKRKEKDHYLL 3513
Query: 457 TVTASEIDNPDLLSHVTVGIRVLDVNDNPPE-LAREYDIIVCENSKPGQVIHTISATDKD 515
V ++ P L S + IRV++ + PP L E I G VI I ATD+D
Sbjct: 3514 QVKVADNGKPQLSSLTYIDIRVIEESIYPPAILPLEIFITSSGEEYSGGVIGKIHATDQD 3573
Score = 172 bits (437), Expect = 8e-43
Identities = 148/517 (28%), Positives = 243/517 (47%), Gaps = 30/517 (5%)
Query: 77 LHSNSDKGDG-SVKYILTGEGAGTIFIIDDTTGDIHSTKSLDREQKTHYVLHAQAIDRRT 135
+H ++ +G V Y +T + F I+ TG I+ LD E Y L +A D T
Sbjct: 2202 VHVQANSPEGLKVFYSITDGDPFSQFTINFNTGVINVIAPLDFEAHPAYKLSIRATDSLT 2261
Query: 136 NKPLEPESEFIIKVQDINDNAPKFTDGPYIVTVPEMSDMGTSVLQVTATDAD-DPTYGNS 194
E + I V DINDN P F Y VT+ E S +GTSV+QV ATD+D +P G S
Sbjct: 2262 GAHAEVFVDII--VDDINDNPPVFAQQSYAVTLSEASVIGTSVVQVRATDSDSEPNRGIS 2319
Query: 195 ARVVYSILQGQPYFSVDPKTGVIRTALHNMDREAREHYSVVIQAKDMAGQVGGLSGSTTV 254
++ + + +F VD TG+I + L +D E +++ ++A D G + LS V
Sbjct: 2320 YQMFGNHSKSHDHFHVDSSTGLI-SLLRTLDYEQSRQHTIFVRAVD--GGMPTLSSDVIV 2376
Query: 255 NITLTDVNDNPPRFPQKHYQLYVPESAQVGSAVGKIKANDADTGSNADMTYSIINGDGMG 314
+ +TD+NDNPP F Q+ Y+ + E A G V +KA DAD+ + YSI++G+
Sbjct: 2377 TVDVTDLNDNPPLFEQQIYEARISEHAPHGHFVTCVKAYDADSSDIDKLQYSILSGNDHK 2436
Query: 315 IFSISTDKETREGILSLKKPLNYEKKKSYTLNIEGANTHLDFRFSHLGPFKDATMLKI-I 373
F I ++ GI++L + K Y+LN+ ++ G F+ +T + + +
Sbjct: 2437 HFVI----DSATGIITLSNLHRHALKPFYSLNLSVSD----------GVFRSSTQVHVTV 2482
Query: 374 VGDVDEPPLFSMPSYLMEVYENAKIGTVVGTVLAQDPDS-TNSLVRYFINYNVEDDRFFN 432
+G P F Y +E+ ENA + T+V V D DS V Y I + DRF+
Sbjct: 2483 IGGNLHSPAFLQNEYEVELAENAPLHTLVMEVKTTDGDSGIYGHVTYHIVNDFAKDRFYI 2542
Query: 433 IDANTGTIRTTKVLDREETPWYNITVTASEIDNPDLLSHVTVGIRVLDVNDNPPEL-ARE 491
+ G I T + LDRE I+V D ++ TV + + D NDN P+ A +
Sbjct: 2543 NE--RGQIFTLEKLDRETPAEKVISVRLMAKDAGGKVAFCTVNVILTDDNDNAPQFRATK 2600
Query: 492 YDIIVCENSKPGQVIHTISATDKDDFANGPRFNFFLDERLPVNPNFTLKDNEDNTASILT 551
Y++ + ++ G + + A+D D+ +N + V N + + + ++T
Sbjct: 2601 YEVNIGSSAAKGTSVVKVLASDADEGSNADITYAIEADSESVKENLEI----NKLSGVIT 2656
Query: 552 RRRRFSRTVQDVYYLPIMISDGGIPSLSSSSTLTIRV 588
+ + + + D G PS S + +++
Sbjct: 2657 TKESLIGLENEFFTFFVRAVDNGSPSKESVVLVYVKI 2693
Score = 171 bits (432), Expect = 3e-42
Identities = 132/456 (28%), Positives = 221/456 (48%), Gaps = 46/456 (10%)
Query: 78 HSNSDKGDGSVKY-ILTGEGAGTIFIIDDTTGDIHSTKSLDREQKTHYVLHAQAIDRRTN 136
H + DG ++Y I G G G +F I + TG I ++ LDRE +HY L A D+
Sbjct: 1059 HDEDARRDGEIRYSIRDGSGVG-VFKIGEETGVIETSDRLDRESTSHYWLTVFATDQGV- 1116
Query: 137 KPLEPESEFIIKVQDINDNAPKFTDGPYIVTVPEMSDMGTSVLQVTATDADDPTYGNSAR 196
PL E I+V+D+NDNAP+ ++ Y + E S SV+Q+ +A DP ++ +
Sbjct: 1117 VPLSSFIEIYIEVEDVNDNAPQTSEPVYYPEIMENSPKDVSVVQI---EAFDPDSSSNDK 1173
Query: 197 VVYSILQGQP--YFSVDPKTGVIRTALHNMDREAREHYSVVIQAKDMAGQVGGLSGSTTV 254
++Y I G P +FS+ PKTG+I T +DRE ++ + + + D S V
Sbjct: 1174 LMYKITSGNPQGFFSIHPKTGLITTTSRKLDREQQDEHILEVTVTDNGSP--PKSTIARV 1231
Query: 255 NITLTDVNDNPPRFPQKHYQLYVPESAQVG-------SAVGKIKANDADTGSNADMTYSI 307
+ + D NDN P+F QK Y++ +PE + + + A D D G NA+++YSI
Sbjct: 1232 IVKILDENDNKPQFLQKFYKIRLPEREKPDRERNARREPLYHVIATDKDEGPNAEISYSI 1291
Query: 308 INGDGMGIFSISTDKETREGILSLKKPLNYEKKKSYTLNIEGANTHLDFRFSHLGPFKDA 367
+G+ G F I E + G++S K+ + G L + G + +
Sbjct: 1292 EDGNEHGKFFI----EPKTGVVSSKR-----------FSAAGEYDILSIKAVDNGRPQKS 1336
Query: 368 TMLKIIVGDVD------EPPLFSMPSYLMEVYENAKIGTVVGTVLAQDPDSTNSLVRYFI 421
+ ++ + + EP F + V E+ + ++G + + P + +F
Sbjct: 1337 STTRLHIEWISKPKPSLEPISFEESFFTFTVMESDPVAHMIGVISVEPP----GIPLWFD 1392
Query: 422 NYNVEDDRFFNIDANTGTIRTTKVLDREETPWYNITVTASEIDNPDLLSHVTVGIRVLDV 481
D F++D TGTI K LD E+ YN+TV A++ L V I+V+D
Sbjct: 1393 ITGGNYDSHFDVDKGTGTIIVAKPLDAEQKSNYNLTVEATDGTTTIL---TQVFIKVIDT 1449
Query: 482 NDNPPELA-REYDIIVCENSKPGQVIHTISATDKDD 516
ND+ P+ + +Y++++ E++ P I ISA D+D+
Sbjct: 1450 NDHRPQFSTSKYEVVIPEDTAPETEILQISAVDQDE 1485
Score = 168 bits (425), Expect = 2e-41
Identities = 152/520 (29%), Positives = 239/520 (45%), Gaps = 38/520 (7%)
Query: 79 SNSDKG-DGSVKYILTGEGAGTI---FIIDDTTGDIHSTKSLDREQKTHYVLHAQAIDRR 134
S++D G +G V Y L + + F I+ TG I + K LD E++ +Y + A D
Sbjct: 2834 SDADSGTNGQVMYSLDQSQSVEVIESFAINMETGWITTLKELDHEKRDNYQIKVVASDHG 2893
Query: 135 TNKPLEPESEFIIKVQDINDNAPKFTDGPYIVTVPEMSDMGTSVLQVTATDADDPTYGNS 194
L + + V D+ND+ P+FT Y TV E G + ++ TDAD +
Sbjct: 2894 EKIQLSSTAIVDVTVTDVNDSPPRFTAEIYKGTVSEDDPQGGVIAILSTTDADSEEI--N 2951
Query: 195 ARVVYSILQGQP--YFSVDPKTGVIRTALHN-MDREAREHYSVVIQAKDMAGQVGGLSGS 251
+V Y I G P F+V+ + + +DRE R++Y + I A D G S
Sbjct: 2952 RQVTYFITGGDPLGQFAVETIQNEWKVYVKKPLDREKRDNYLLTITATD-----GTFSSK 3006
Query: 252 TTVNITLTDVNDNPPRFPQKHYQLYVPESAQVGSAVGKIKANDADTGSNADMTYSIINGD 311
V + + D NDN P + Y +PE G + +I A DAD SNA++TY+++ G
Sbjct: 3007 AIVEVKVLDANDNSPVCEKTLYSDTIPEDVLPGKLIMQISATDADIRSNAEITYTLL-GS 3065
Query: 312 GMGIFSISTDKETREGILSLKKPLNYEKKKSYTLNIEGANTHLDFRFSHLGPFKDATMLK 371
G F ++ D G L PL+ E++ Y L + + G F A+++
Sbjct: 3066 GAEKFKLNPD----TGELKTSTPLDREEQAVYHLLVRATDGG--------GRFCQASIVL 3113
Query: 372 IIVGDVDEPPLFSMPSYLMEVYENAKIGTVVGTVLAQDPDS-TNSLVRYFINYNVEDDRF 430
+ D P FS Y + V+EN + GT++ V A D D+ N + Y + + D
Sbjct: 3114 TLEDVNDNAPEFSADPYAITVFENTEPGTLLTRVQATDADAGLNRKILYSLIDSA--DGQ 3171
Query: 431 FNIDANTGTIRTTKVLDREETPWYNITVTASEIDNPDLLSHV-TVGIRVLDVNDNPPELA 489
F+I+ +G I+ K LDRE Y +++ A + P L+ TV + VLD+NDNPP
Sbjct: 3172 FSINELSGIIQLEKPLDRELQAVYTLSLKAVDQGLPRRLTATGTVIVSVLDINDNPPVFE 3231
Query: 490 -REYDIIVCENSKPGQVIHTISATDKDDFANGPRFNFFLDERLPVNPNFTLKDNEDNTAS 548
REY V E+ G + + A +D AN + + ++ N K + D+
Sbjct: 3232 YREYGATVSEDILVGTEVLQVYAASRDIEANA-EITYSI-----ISGNEHGKFSIDSKTG 3285
Query: 549 ILTRRRRFSRTVQDVYYLPIMISDGGIPSLSSSSTLTIRV 588
+ YYL + +DGG PSLS +T+ + V
Sbjct: 3286 AVFIIENLDYESSHEYYLTVEATDGGTPSLSDVATVNVNV 3325
Score = 164 bits (416), Expect = 2e-40
Identities = 131/433 (30%), Positives = 210/433 (48%), Gaps = 42/433 (9%)
Query: 101 FIIDDTTGDIHSTKSLDREQKTHYVLHAQAIDRRTNKPLEPE-SEFIIKVQDINDNAPKF 159
F +D TG +++++ LD E + L D+ + P++ + ++ V D ND+AP F
Sbjct: 1505 FRLDPATGSLYTSEKLDHEAVHQHTLTVMVRDQ--DVPVKRNFARIVVNVSDTNDHAPWF 1562
Query: 160 TDGPYIVTVPEMSDMGTSVLQVTATDADDPTYGNSARVVYSILQGQ--PYFSVDPKTGVI 217
T Y V E + +G+ VLQVTA D D G +A V+YSI G F +DP G I
Sbjct: 1563 TASSYKGRVYESAAVGSVVLQVTALDKDK---GKNAEVLYSIESGNIGNSFMIDPVLGSI 1619
Query: 218 RTALHNMDREAREHYSVVIQAKDMAGQVGGLSGSTTVNITLTDVNDNPPRFPQKHYQLYV 277
+TA +DR + Y ++++A D +S T+V I +T ++ P+F K Y + +
Sbjct: 1620 KTA-KELDRSNQAEYDLMVKATDKGSPP--MSEITSVRIFVTIADNASPKFTSKEYSVEL 1676
Query: 278 PESAQVGSAVGKIKANDADTGSNADMTYSIINGDGMGIFSISTDKETREGILSLKKPLNY 337
E+ +GS VG + A+ S + + Y I +G+ F I+ G + +K L++
Sbjct: 1677 SETVSIGSFVGMVTAH-----SQSSVVYEIKDGNTGDAFDINP----HSGTIITQKALDF 1727
Query: 338 EKKKSYTLNIEGANTHLDFRFSHLGPFKDATMLKIIVGDVDEPPLFSMPSYLMEVYENAK 397
E YTL I+G N G + T+L + + D P+F Y + E+A
Sbjct: 1728 ETLPIYTLIIQGTNM--------AGLSTNTTVLVHLQDENDNAPVFMQAEYTGLISESAS 1779
Query: 398 IGTVVGT---------VLAQDPDSTNSLVRYFINYNVEDDRFFNIDANTGTIRTTKVLDR 448
I +VV T D DS LV + + +V +F ID++TG I T LD
Sbjct: 1780 INSVVLTDRNVPLVIRAADADKDSNALLVYHIVEPSVHT--YFAIDSSTGAIHTVLSLDY 1837
Query: 449 EETPWYNITVTASEIDNPDLLSH--VTVGIRVLDVNDNPPELARE-YDIIVCENSKPGQV 505
EET ++ TV ++ P L + V + V+D+ND PP A+ Y+ + + G
Sbjct: 1838 EETSIFHFTVQVHDMGTPRLFAEYAANVTVHVIDINDCPPVFAKPLYEASLLLPTYKGVK 1897
Query: 506 IHTISATDKDDFA 518
+ T++ATD D A
Sbjct: 1898 VITVNATDADSSA 1910
Score = 157 bits (396), Expect = 5e-38
Identities = 140/511 (27%), Positives = 233/511 (45%), Gaps = 50/511 (9%)
Query: 92 LTGEGAGTIFIIDDTTGDIHSTKSLDREQKTHYVLHAQAIDRRTNKPLEPESEFIIKVQD 151
+TG + F +D TG I K LD EQK++Y L +A D T ++ IKV D
Sbjct: 1393 ITGGNYDSHFDVDKGTGTIIVAKPLDAEQKSNYNLTVEATDGTTTIL----TQVFIKVID 1448
Query: 152 INDNAPKFTDGPYIVTVPEMSDMGTSVLQVTATDADDPTYGNSARVVYSILQGQP----- 206
ND+ P+F+ Y V +PE + T +LQ++A D D+ +++Y++ +
Sbjct: 1449 TNDHRPQFSTSKYEVVIPEDTAPETEILQISAVDQDEKN-----KLIYTLQSSRDPLSLK 1503
Query: 207 YFSVDPKTGVIRTALHNMDREAREHYSVVIQAKDMAGQVGGLSGSTTVNITLTDVNDNPP 266
F +DP TG + T+ +D EA +++ + +D V VN++ D ND+ P
Sbjct: 1504 KFRLDPATGSLYTS-EKLDHEAVHQHTLTVMVRDQDVPVKRNFARIVVNVS--DTNDHAP 1560
Query: 267 RFPQKHYQLYVPESAQVGSAVGKIKANDADTGSNADMTYSIINGDGMGIFSISTDKETRE 326
F Y+ V ESA VGS V ++ A D D G NA++ YSI +G+ F I +
Sbjct: 1561 WFTASSYKGRVYESAAVGSVVLQVTALDKDKGKNAEVLYSIESGNIGNSFMI----DPVL 1616
Query: 327 GILSLKKPLNYEKKKSYTLNIEGANTHLDFRFSHLGPFKDATMLKIIVGDVDE-PPLFSM 385
G + K L+ + Y L ++ + P + T ++I V D P F+
Sbjct: 1617 GSIKTAKELDRSNQAEYDLMVKATD-------KGSPPMSEITSVRIFVTIADNASPKFTS 1669
Query: 386 PSYLMEVYENAKIGTVVGTVLAQDPDSTNSLVRYFINYNVEDDRFFNIDANTGTIRTTKV 445
Y +E+ E IG+ VG V A S +S+V + N D F+I+ ++GTI T K
Sbjct: 1670 KEYSVELSETVSIGSFVGMVTAH---SQSSVVYEIKDGNTGD--AFDINPHSGTIITQKA 1724
Query: 446 LDREETPWYNITVTASEIDNPDLLSHVTVGIRVLDVNDNPPE-LAREYDIIVCENSKPGQ 504
LD E P Y + + + + L ++ TV + + D NDN P + EY ++ E++
Sbjct: 1725 LDFETLPIYTLIIQGTNM--AGLSTNTTVLVHLQDENDNAPVFMQAEYTGLISESASINS 1782
Query: 505 VIHT-------ISATDKDDFANGPRFNFFLDERLPVNPNFTLKDNEDNTASILTRRRRFS 557
V+ T I A D D +N ++ V+ F + + ++L+
Sbjct: 1783 VVLTDRNVPLVIRAADADKDSNALLVYHIVEP--SVHTYFAIDSSTGAIHTVLS----LD 1836
Query: 558 RTVQDVYYLPIMISDGGIPSLSSSSTLTIRV 588
+++ + + D G P L + + V
Sbjct: 1837 YEETSIFHFTVQVHDMGTPRLFAEYAANVTV 1867
Score = 154 bits (388), Expect = 4e-37
Identities = 146/534 (27%), Positives = 244/534 (45%), Gaps = 45/534 (8%)
Query: 101 FIIDDTTGDIHSTKSLDREQKTHYVLHAQAIDRRTNKPLEPESEFIIKVQDINDNAPKFT 160
F+ID TG I + K Y L+ D ++ + V N ++P F
Sbjct: 2438 FVIDSATGIITLSNLHRHALKPFYSLNLSVSDG----VFRSSTQVHVTVIGGNLHSPAFL 2493
Query: 161 DGPYIVTVPEMSDMGTSVLQVTATDADDPTYGNSARVVYSILQ--GQPYFSVDPKTGVIR 218
Y V + E + + T V++V TD D YG+ V Y I+ + F ++ + +
Sbjct: 2494 QNEYEVELAENAPLHTLVMEVKTTDGDSGIYGH---VTYHIVNDFAKDRFYINERGQIF- 2549
Query: 219 TALHNMDRE--AREHYSVVIQAKDMAGQVGGLSGSTTVNITLTDVNDNPPRFPQKHYQLY 276
L +DRE A + SV + AKD G+V TVN+ LTD NDN P+F Y++
Sbjct: 2550 -TLEKLDRETPAEKVISVRLMAKDAGGKVA----FCTVNVILTDDNDNAPQFRATKYEVN 2604
Query: 277 VPESAQVGSAVGKIKANDADTGSNADMTYSIINGDGMGIFSISTDKETREGILSLKKPLN 336
+ SA G++V K+ A+DAD GSNAD+TY+ I D + + + G+++ K+ L
Sbjct: 2605 IGSSAAKGTSVVKVLASDADEGSNADITYA-IEADSESV-KENLEINKLSGVITTKESLI 2662
Query: 337 YEKKKSYTLNIEGANTHLDFRFSHLGPFKDATML---KIIVGDVDEPPLFSMPSYLMEVY 393
+ + +T + + P K++ +L KI+ ++ + P FS P Y V
Sbjct: 2663 GLENEFFTFFVRAVDNG--------SPSKESVVLVYVKILPPEM-QLPKFSEPFYTFTVS 2713
Query: 394 ENAKIGTVVGTVLAQDPDSTNSLVRYFINYNVED---DRFFNIDANTGTIRTTKVLDREE 450
E+ IGT + + A + + +++ + N + D F ID +G ++ K LD E
Sbjct: 2714 EDVPIGTEIDLIRA---EHSGTVLYSLVKGNTPESNRDESFVIDRQSGRLKLEKSLDHET 2770
Query: 451 TPWYNITVTA-SEIDNPDLLSHVTVGIRVLDVNDNPPEL-AREYDIIVCENSKPGQVIHT 508
T WY ++ A D+ ++++ V V I+V D NDN P + Y+ + EN G +
Sbjct: 2771 TKWYQFSILARCTQDDHEMVASVDVSIQVKDANDNSPVFESSPYEAFIVENLPGGSRVIQ 2830
Query: 509 ISATDKDDFANGPRFNFFLDERLPVNPNFTLKDNEDNTASILTRRRRFSRTVQDVYYLPI 568
I A+D D NG + + LD+ V + N + +T + +D Y + +
Sbjct: 2831 IRASDADSGTNG-QVMYSLDQSQSVEVIESFAINME--TGWITTLKELDHEKRDNYQIKV 2887
Query: 569 MISDGGIPSLSSSSTLTIRVCACERDGRVRTCHAEAFLSSAGLS--TGALIAIL 620
+ SD G + SST + V + + AE + + G +IAIL
Sbjct: 2888 VASDHG-EKIQLSSTAIVDVTVTDVNDSPPRFTAEIYKGTVSEDDPQGGVIAIL 2940
Score = 152 bits (383), Expect = 2e-36
Identities = 139/506 (27%), Positives = 245/506 (48%), Gaps = 37/506 (7%)
Query: 94 GEGAGTIFIIDDTTGDIHSTKSLDREQKTHYVLHAQAIDRRTNKPLEPESEFII-KVQDI 152
GE T I+ T H +L E+ + A+ + + + E E I +
Sbjct: 650 GENFATPLYINITVAASHKLVNLQCEETGVAKMLAEKLLQANKLHNQGEVEDIFFDSHSV 709
Query: 153 NDNAPKFTDG-PYIVTVPEMSDMGTSVLQVTATDADDPTYGNSARVVYSILQG--QPYFS 209
N + P+F P + V E +G+SV+ + +TD D G + ++VY++ G F
Sbjct: 710 NAHIPQFRSTLPTGIQVKENQPVGSSVIFMNSTDLDT---GFNGKLVYAVSGGNEDSCFM 766
Query: 210 VDPKTGVIRTALHNMDREAREHYSVVIQAKDMAGQVGGLSGSTTVNITLTDVNDNPPRFP 269
+D +TG+++ L +DRE + Y++ I D+ + + +++ + D NDNPP F
Sbjct: 767 IDMETGMLK-ILSPLDRETTDKYTLNITVYDLG--IPQKAAWRLLHVVVVDANDNPPEFL 823
Query: 270 QKHYQLYVPESAQVGSAVGKIKANDADTGSNADMTYSII-NGDGMGIFSISTDKETREGI 328
Q+ Y + V E +V S + +++A D D G N +TYSI+ + D I S++ G+
Sbjct: 824 QESYFVEVSEDKEVHSEIIQVEATDKDLGPNGHVTYSIVTDTDTFSIDSVT-------GV 876
Query: 329 LSLKKPLNYEKKKSYTLNIEGANTHLDFRFSHLGPFKDATMLKIIVGDV-DEPPLFSMPS 387
+++ +PL+ E + ++L IE + + ++K+ + DV D PP F P+
Sbjct: 877 VNIARPLDRELQHEHSLKIEARD-----QAREEPQLFSTVVVKVSLEDVNDNPPTFIPPN 931
Query: 388 YLMEVYENAKIGTVVGTVLAQDPD-STNSLVRYFINYNVEDDRFFNIDANTGTIRTTKVL 446
Y ++V E+ GTV+ + A DPD + VRY + + E + F++D +G +R + L
Sbjct: 932 YRVKVREDLPEGTVIMWLEAHDPDLGQSGQVRYSLLDHGEGN--FDVDKLSGAVRIVQQL 989
Query: 447 DREETPWYNITVTASEIDNP-DLLSHVTVGIRVLDVNDN--PPELAREYDI-IVCENSKP 502
D E+ YN+TV A + P L S V + V+DVN+N PP + + V E++
Sbjct: 990 DFEKKQVYNLTVRAKDKGKPVSLSSTCYVEVEVVDVNENLHPPVFSSFVEKGTVKEDAPV 1049
Query: 503 GQVIHTISATDKDDFANGPRFNFFLDERLPVNPNFTLKDNEDNTASILTRRRRFSRTVQD 562
G ++ T+SA D+D +G + + + V K E+ ++ R R
Sbjct: 1050 GSLVMTVSAHDEDARRDG-EIRYSIRDGSGVG---VFKIGEE--TGVIETSDRLDRESTS 1103
Query: 563 VYYLPIMISDGGIPSLSSSSTLTIRV 588
Y+L + +D G+ LSS + I V
Sbjct: 1104 HYWLTVFATDQGVVPLSSFIEIYIEV 1129
Score = 141 bits (356), Expect = 2e-33
Identities = 137/528 (25%), Positives = 232/528 (43%), Gaps = 50/528 (9%)
Query: 73 YVGKLHSNSDKGDGSVKYILTGEGAGTIFIIDDTTGDIHSTKSLDREQKTHYVLHAQAID 132
+VG + ++S SV Y + G F I+ +G I + K+LD E Y L Q +
Sbjct: 1685 FVGMVTAHSQS---SVVYEIKDGNTGDAFDINPHSGTIITQKALDFETLPIYTLIIQGTN 1741
Query: 133 RRTNKPLEPESEFIIKVQDINDNAPKFTDGPYIVTVPEMSDMGTSVLQ-------VTATD 185
L + ++ +QD NDNAP F Y + E + + + VL + A D
Sbjct: 1742 MAG---LSTNTTVLVHLQDENDNAPVFMQAEYTGLISESASINSVVLTDRNVPLVIRAAD 1798
Query: 186 ADDPTYGNSARVVYSILQGQ--PYFSVDPKTGVIRTALHNMDREAREHYSVVIQAKDMAG 243
AD + +A +VY I++ YF++D TG I T L ++D E + +Q DM
Sbjct: 1799 ADKDS---NALLVYHIVEPSVHTYFAIDSSTGAIHTVL-SLDYEETSIFHFTVQVHDMGT 1854
Query: 244 QVGGLSGSTTVNITLTDVNDNPPRFPQKHYQLYVPESAQVGSAVGKIKANDADTGSNADM 303
+ V + + D+ND PP F + Y+ + G V + A DAD+ + + +
Sbjct: 1855 PRLFAEYAANVTVHVIDINDCPPVFAKPLYEASLLLPTYKGVKVITVNATDADSSAFSQL 1914
Query: 304 TYSIINGDGMGIFSISTDKETREGILSLKKPLNYEKKKSYTLNIEGANTHLDFRFSHLGP 363
YSI G+ FS+ + + G L+++ + + Y L + ++ G
Sbjct: 1915 IYSITEGNIGEKFSM----DYKTGALTVQN--TTQLRSRYELTVRASD----------GR 1958
Query: 364 FKDATMLKIIVGDVDEPPL-FSMPSYLMEVYENAKIGTVVGTVLAQDPDSTNSLVRYFIN 422
F T +KI V + E L F+ Y V EN+ + + A L + +N
Sbjct: 1959 FAGLTSVKINVKESKESHLKFTQDVYSAVVKENSTEAETLAVITAIGNPINEPLFYHILN 2018
Query: 423 YNVEDDRFFNIDANTGTIRTTKV-LDREETPWYNITVTASEIDNPDLLSHVTVGIRVLDV 481
DR F I +G + TT DRE+ +++ V +E P ++HV V + V D
Sbjct: 2019 ----PDRRFKISRTSGVLSTTGTPFDREQQEAFDVVVEVTEEHKPSAVAHVVVKVIVEDQ 2074
Query: 482 NDNPPELAR-EYDIIVCENSKPGQVIHTISATDKDDFANGPRFNFFLDERLPVNPNFTLK 540
NDN P Y +V +++ G VI ++A D+D NG +++L E + +F +
Sbjct: 2075 NDNAPVFVNLPYYAVVKVDTEVGHVIRYVTAVDRDSGRNG-EVHYYLKEH---HEHFQI- 2129
Query: 541 DNEDNTASILTRRRRFSRTVQDVYYLPIMISDGGIPSLSSSSTLTIRV 588
I +++ T+ Y + ++ DGG P+ S+ + I V
Sbjct: 2130 ---GPLGEISLKKQFELDTLNKEYLVTVVAKDGGNPAFSAEVIVPITV 2174
Score = 130 bits (326), Expect = 6e-30
Identities = 146/516 (28%), Positives = 231/516 (44%), Gaps = 61/516 (11%)
Query: 80 NSDKG-DGSVKYILTGEGAGTIFIIDDTTGDIHSTKSLDREQKTHYVLHAQAIDRRTNKP 138
+ DKG + V Y + G F+ID G I + K LDR + Y L +A D + + P
Sbjct: 1588 DKDKGKNAEVLYSIESGNIGNSFMIDPVLGSIKTAKELDRSNQAEYDLMVKATD-KGSPP 1646
Query: 139 LEPESEFIIKVQDINDNAPKFTDGPYIVTVPEMSDMGTSVLQVTATDADDPTYGNSARVV 198
+ + I V ++ +PKFT Y V + E +G+ V VTA + + VV
Sbjct: 1647 MSEITSVRIFVTIADNASPKFTSKEYSVELSETVSIGSFVGMVTA--------HSQSSVV 1698
Query: 199 YSILQGQ--PYFSVDPKTGVIRTALHNMDREAREHYSVVIQAKDMAGQVGGLSGSTTVNI 256
Y I G F ++P +G I T +D E Y+++IQ +MA GLS +TTV +
Sbjct: 1699 YEIKDGNTGDAFDINPHSGTIITQ-KALDFETLPIYTLIIQGTNMA----GLSTNTTVLV 1753
Query: 257 TLTDVNDNPPRFPQKHYQLYVPESAQVGSAVGK-------IKANDADTGSNADMTYSIIN 309
L D NDN P F Q Y + ESA + S V I+A DAD SNA + Y I+
Sbjct: 1754 HLQDENDNAPVFMQAEYTGLISESASINSVVLTDRNVPLVIRAADADKDSNALLVYHIVE 1813
Query: 310 GDGMGIFSISTDKETREGILSLKKPLNYEKKKSYTLNIEGANTHLDFRFSHLGPFKDATM 369
F+I + +LS L+YE+ + ++ + F+ A
Sbjct: 1814 PSVHTYFAIDSSTGAIHTVLS----LDYEETSIFHFTVQVHDMGTPRLFAEY-----AAN 1864
Query: 370 LKIIVGDVDE-PPLFSMPSYLMEVYENAKIGTVVGTVLAQDPDST--NSLVRYFINYNVE 426
+ + V D+++ PP+F+ P Y + G V TV A D DS+ + L+ N+
Sbjct: 1865 VTVHVIDINDCPPVFAKPLYEASLLLPTYKGVKVITVNATDADSSAFSQLIYSITEGNIG 1924
Query: 427 DDRFFNIDANTGTI---RTTKVLDREETPWYNITVTASEIDNPDLLSHVTVGIRVLDVND 483
+ F++D TG + TT++ R Y +TV AS+ L S V I V + +
Sbjct: 1925 EK--FSMDYKTGALTVQNTTQLRSR-----YELTVRASDGRFAGLTS---VKINVKESKE 1974
Query: 484 NPPELARE-YDIIVCENSKPGQVIHTISATDKDDFANGPRFNFFLDERLPVNPNFTLKDN 542
+ + ++ Y +V ENS + + I+A N P F L NP+ K +
Sbjct: 1975 SHLKFTQDVYSAVVKENSTEAETLAVITAIGNP--INEPLFYHIL------NPDRRFKIS 2026
Query: 543 EDNTASIL-TRRRRFSRTVQDVYYLPIMISDGGIPS 577
T+ +L T F R Q+ + + + +++ PS
Sbjct: 2027 --RTSGVLSTTGTPFDREQQEAFDVVVEVTEEHKPS 2060
Score = 123 bits (309), Expect = 6e-28
Identities = 133/545 (24%), Positives = 229/545 (42%), Gaps = 71/545 (13%)
Query: 88 VKYILTGEGAGTIFIIDDTTGDIHSTKSLDREQKTHYVLHAQAIDRRTNKPLEPESEFII 147
++Y+ F ++ TG I + + R+Q H+ L DR+ + ++ ++
Sbjct: 398 LRYVFKSTPGKAKFSLNYNTGLISILEPVKRQQAAHFELEVTTSDRKAS------TKVLV 451
Query: 148 KVQDINDNAPKFTDGPYIVTVPEMSDMGTSVLQVTATDADDPTYGNSARVVYSILQ-GQP 206
KV N N P+FT Y E +GT+V+ ++A D D+ G + V YSI
Sbjct: 452 KVLGANSNPPEFTQTAYKAAFDENVPIGTTVMSLSAVDPDE---GENGYVTYSIANLNHV 508
Query: 207 YFSVDPKTGVIRTALHNMDREAREH-YSVVIQAKDMAGQVGGLSGSTTVNITLTDVNDNP 265
F++D TG + T+ N+D E Y++ I+A D G ITL ++NDN
Sbjct: 509 PFAIDHFTGAVSTS-ENLDYELMPRVYTLRIRASDW-GLPYRREVEVLATITLNNLNDNT 566
Query: 266 PRFPQKHYQLYVPESAQVGSAVGKIKANDADTGSNADMTYSIINGDGMGIFSISTDKETR 325
P F + + + +P VG + + A DAD + Y I G+ + FS++ +
Sbjct: 567 PLFEKINCEGTIPRDLGVGEQITTVSAIDAD--ELQLVQYQIEAGNELDFFSLNPN---- 620
Query: 326 EGILSLKKPL---------------------NYEKKKSYTLNIEGANTHLDFRFSHLGPF 364
G+LSLK+ L N+ + + ++ ++ + G
Sbjct: 621 SGVLSLKRSLMDGLGAKVSFHSLRITATDGENFATPLYINITVAASHKLVNLQCEETGVA 680
Query: 365 KDATMLKIIV------GDVDE------------PPLFSMPSYLMEVYENAKIGTVVGTVL 406
K + G+V++ P S ++V EN +G+ V +
Sbjct: 681 KMLAEKLLQANKLHNQGEVEDIFFDSHSVNAHIPQFRSTLPTGIQVKENQPVGSSVIFMN 740
Query: 407 AQDPDS-TNSLVRYFINYNVEDDRFFNIDANTGTIRTTKVLDREETPWYNITVTASEIDN 465
+ D D+ N + Y ++ ED F ID TG ++ LDRE T Y + +T ++
Sbjct: 741 STDLDTGFNGKLVYAVSGGNEDSCFM-IDMETGMLKILSPLDRETTDKYTLNITVYDLGI 799
Query: 466 PDLLSHVTVGIRVLDVNDNPPELARE-YDIIVCENSKPGQVIHTISATDKDDFANG-PRF 523
P + + + V+D NDNPPE +E Y + V E+ + I + ATDKD NG +
Sbjct: 800 PQKAAWRLLHVVVVDANDNPPEFLQESYFVEVSEDKEVHSEIIQVEATDKDLGPNGHVTY 859
Query: 524 NFFLDERLPVNPNFTLKDNEDNTASILTRRRRFSRTVQDVYYLPIMISDGGIPSLSSSST 583
+ D F++ D+ ++ R R +Q + L I D ST
Sbjct: 860 SIVTD-----TDTFSI----DSVTGVVNIARPLDRELQHEHSLKIEARDQAREEPQLFST 910
Query: 584 LTIRV 588
+ ++V
Sbjct: 911 VVVKV 915
Score = 112 bits (279), Expect = 2e-24
Identities = 130/517 (25%), Positives = 212/517 (41%), Gaps = 70/517 (13%)
Query: 90 YILTGEGAGTIFIIDDTTGDIHSTKSLDREQKTHYVLHAQAIDRRTNKPLEPESEFIIKV 149
Y +T G F +D TG + T + ++ Y L +A D R + I V
Sbjct: 1916 YSITEGNIGEKFSMDYKTGAL--TVQNTTQLRSRYELTVRASDGR----FAGLTSVKINV 1969
Query: 150 QDINDNAPKFTDGPYIVTVPEMSDMGTSVLQVTA--TDADDPTYGNSARVVYSILQGQPY 207
++ ++ KFT Y V E S ++ +TA ++P + Y IL
Sbjct: 1970 KESKESHLKFTQDVYSAVVKENSTEAETLAVITAIGNPINEPLF-------YHILNPDRR 2022
Query: 208 FSVDPKTGVIRTALHNMDREAREHYSVVIQAKDMAGQVGGLSGSTTVNITLTDVNDNPPR 267
F + +GV+ T DRE +E + VV++ + V + + D NDN P
Sbjct: 2023 FKISRTSGVLSTTGTPFDREQQEAFDVVVEVTEE--HKPSAVAHVVVKVIVEDQNDNAPV 2080
Query: 268 FPQKHYQLYVPESAQVGSAVGKIKANDADTGSNADMTYSIINGDGMGIFSISTDKETRE- 326
F Y V +VG + + A D D+G N ++ Y + KE E
Sbjct: 2081 FVNLPYYAVVKVDTEVGHVIRYVTAVDRDSGRNGEVHYYL--------------KEHHEH 2126
Query: 327 ------GILSLKKPLNYEK-KKSYTLNI---EGANTHLDFRFSHLGPFKDATMLKIIVGD 376
G +SLKK + K Y + + +G N P A ++ I
Sbjct: 2127 FQIGPLGEISLKKQFELDTLNKEYLVTVVAKDGGN-----------PAFSAEVIVPITVM 2175
Query: 377 VDEPPLFSMPSYLMEVYENAKIGTVVGTVLAQDPDSTNSLVRYFINYNVED-DRF--FNI 433
P+F P Y E+ E+ ++ + V V A P+ + Y++ D D F F I
Sbjct: 2176 NKAMPVFEKPFYSAEIAESIQVHSPVVHVQANSPEGLK------VFYSITDGDPFSQFTI 2229
Query: 434 DANTGTIRTTKVLDREETPWYNITVTASEIDNPDLLSHVTVGIRVLDVNDNPPELARE-Y 492
+ NTG I LD E P Y +++ A++ + V V I V D+NDNPP A++ Y
Sbjct: 2230 NFNTGVINVIAPLDFEAHPAYKLSIRATD-SLTGAHAEVFVDIIVDDINDNPPVFAQQSY 2288
Query: 493 DIIVCENSKPGQVIHTISATDKDDFAN-GPRFNFFLDERLPVNPNFTLKDNEDNTASILT 551
+ + E S G + + ATD D N G + F + +F + D++ +++
Sbjct: 2289 AVTLSEASVIGTSVVQVRATDSDSEPNRGISYQMF-GNHSKSHDHF----HVDSSTGLIS 2343
Query: 552 RRRRFSRTVQDVYYLPIMISDGGIPSLSSSSTLTIRV 588
R + + + DGG+P+LSS +T+ V
Sbjct: 2344 LLRTLDYEQSRQHTIFVRAVDGGMPTLSSDVIVTVDV 2380
Score = 107 bits (267), Expect = 4e-23
Identities = 119/469 (25%), Positives = 202/469 (43%), Gaps = 30/469 (6%)
Query: 112 STKSLDREQKTHYVLHAQAIDRRTNKPLEPESEFIIKVQDINDNAPKFTDGPYIVTVPEM 171
+T L+RE K HY L +A+++ TN +E ++ ++V D ND P F+ Y V++PE
Sbjct: 104 NTAILNREVKDHYTLIVKALEKNTN--VEARTKVRVQVLDTNDLRPLFSPTSYSVSLPEN 161
Query: 172 SDMGTSVLQVTATDADDPTYGNSARVVYSILQGQPYFSVDPKTGVIRTALHNMDREAREH 231
+ + TS+ +V+ATDAD G + YS F++ P +GVI +D +
Sbjct: 162 TAIRTSIARVSATDAD---IGTNGEFYYSFKDRTDMFAIHPTSGVI-VLTGRLDYLETKL 217
Query: 232 YSVVIQAKDMAGQVGGLSGSTTVNITLTDVNDNPPRFPQKHYQLYVPESAQVGSAVGKIK 291
Y + I A D ++ G SG +++ + P P A +
Sbjct: 218 YEMEILAADRGMKLYGSSGISSMAKLTVHIEQANECAPVITAVTLSPSELDRDPAYAIVT 277
Query: 292 ANDADTGSNADM-TYSIINGDGMGIF-SISTDKETREGILSLKKPLNYEKKK-SYTLNIE 348
+D D G+N D+ + SI+ GD + F ++ + ++E + ++++ Y L ++
Sbjct: 278 VDDCDQGANGDIASLSIVAGDLLQQFRTVRSFPGSKEYKVKAIGGIDWDSHPFGYNLTLQ 337
Query: 349 GANTHLDFRFSHLGPFKDATMLKIIVGDVDEPPLFSMPSYLMEVYENAKIGTVVGTVLAQ 408
+ +FS + T + G P F Y E+ E A T V V A
Sbjct: 338 AKDKGTPPQFSSVKVI-HVTSPQFKAG----PVKFEKDVYRAEISEFAPPNTPVVMVKA- 391
Query: 409 DPDSTNSLVRYFINYNVEDDRFFNIDANTGTIRTTKVLDREETPWYNITVTASEIDNPDL 468
S +RY + F+++ NTG I + + R++ + + VT S D
Sbjct: 392 --IPAYSHLRYVFK-STPGKAKFSLNYNTGLISILEPVKRQQAAHFELEVTTS-----DR 443
Query: 469 LSHVTVGIRVLDVNDNPPELAR-EYDIIVCENSKPGQVIHTISATDKDDFANGPRFNFFL 527
+ V ++VL N NPPE + Y EN G + ++SA D D+ NG ++
Sbjct: 444 KASTKVLVKVLGANSNPPEFTQTAYKAAFDENVPIGTTVMSLSAVDPDEGENG-----YV 498
Query: 528 DERLPVNPNFTLKDNEDNTASILTRRRRFSRTVQDVYYLPIMISDGGIP 576
+ N N + T ++ T + VY L I SD G+P
Sbjct: 499 TYSI-ANLNHVPFAIDHFTGAVSTSENLDYELMPRVYTLRIRASDWGLP 546
Score = 87.4 bits (215), Expect = 5e-17
Identities = 96/355 (27%), Positives = 158/355 (44%), Gaps = 47/355 (13%)
Query: 124 YVLHAQAIDRRTNKPLEPESEFIIKVQDINDNAPKFTDGP-------YIVTVPEMSDMGT 176
Y L QA D+ T P +KV I+ +P+F GP Y + E + T
Sbjct: 332 YNLTLQAKDKGT-----PPQFSSVKV--IHVTSPQFKAGPVKFEKDVYRAEISEFAPPNT 384
Query: 177 SVLQVTATDADDPTYGNSARVVYSILQGQPYFSVDPKTGVIRTALHNMDREAREHYSVVI 236
V+ V A P Y + R V+ G+ FS++ TG+I + L + R+ H+ + +
Sbjct: 385 PVVMVKAI----PAYSH-LRYVFKSTPGKAKFSLNYNTGLI-SILEPVKRQQAAHFELEV 438
Query: 237 QAKDMAGQVGGLSGSTTVNITLTDVNDNPPRFPQKHYQLYVPESAQVGSAVGKIKANDAD 296
D ST V + + N NPP F Q Y+ E+ +G+ V + A D D
Sbjct: 439 TTSDR-------KASTKVLVKVLGANSNPPEFTQTAYKAAFDENVPIGTTVMSLSAVDPD 491
Query: 297 TGSNADMTYSIINGDGMGIFSISTDKETREGILSLKKPLNYE-KKKSYTLNIEGANTHLD 355
G N +TYSI N + + D T G +S + L+YE + YTL I ++ L
Sbjct: 492 EGENGYVTYSIAN---LNHVPFAIDHFT--GAVSTSENLDYELMPRVYTLRIRASDWGLP 546
Query: 356 FRFSHLGPFKDATMLKIIVGD--VDEPPLFSMPSYLMEVYENAKIGTVVGTVLAQDPDST 413
+R ++ +L I + D PLF + + + +G + TV A D D
Sbjct: 547 YR-------REVEVLATITLNNLNDNTPLFEKINCEGTIPRDLGVGEQITTVSAIDADEL 599
Query: 414 NSLVRYFINYNVEDDRFFNIDANTGTIRTTKVLD---REETPWYNITVTASEIDN 465
LV+Y I E D FF+++ N+G + + L + ++++ +TA++ +N
Sbjct: 600 -QLVQYQIEAGNELD-FFSLNPNSGVLSLKRSLMDGLGAKVSFHSLRITATDGEN 652
>gi|29570800 cadherin-like 26 isoform a [Homo sapiens]
Length = 832
Score = 219 bits (559), Expect = 6e-57
Identities = 215/806 (26%), Positives = 364/806 (45%), Gaps = 101/806 (12%)
Query: 50 RPKRGWVWNQFFVLEEHMGPDPQYVGKLHSNSDKGDGSVKYILTGEGA------GTIFII 103
R KR WV + EE GP P+ +G+L +N + S+ Y+++G G G +
Sbjct: 51 RSKRRWVITTLELEEEDPGPFPKLIGELFNNMSY-NMSLMYLISGPGVDEYPEIGLFSLE 109
Query: 104 DDTTGDIHSTKSLDREQKTHYVLHAQAIDRRTNKPLEPESEFIIKVQDINDNAPKFTDGP 163
D G I+ + +DRE + ++ ++R T K ++ F I++ D+ND+AP+F +
Sbjct: 110 DHENGRIYVHRPVDREMTPSFTVYFDVVERSTGKIVDTSLIFNIRISDVNDHAPQFPEKE 169
Query: 164 YIVTVPEMSDMGTSVLQVTATDADDPTYGNSARVVYSILQGQPY-----FSVDPKTGVIR 218
+ +TV E G + Q+ A D D+ NS +V+Y ++ P F VD +G IR
Sbjct: 170 FNITVQENQSAGQPIFQMLAVDLDEENTPNS-QVLYFLISQTPLLKESGFRVDRLSGEIR 228
Query: 219 TALHNMDREAREHYSVVIQAKDMAGQVGGLSGSTTVNITLTDVNDNPPRFPQKHYQLYVP 278
+ +D E ++++I+A+D LS +TTV++ + + N++ P F Q++Y++ +P
Sbjct: 229 LS-GCLDYETAPQFTLLIRARDCGEP--SLSSTTTVHVDVQEGNNHRPAFTQENYKVQIP 285
Query: 279 ES-AQVGSAVGKIKANDADTGSNADMTYSIINGDGMGIFSISTDKETREGILSLKKPLNY 337
E A G ++ D+ S ++I++G+ G F ISTD ET EGIL++ KPL+Y
Sbjct: 286 EGRASQGVLRLLVQDRDSPFTSAWRAKFNILHGNEEGHFDISTDPETNEGILNVIKPLDY 345
Query: 338 EKK--KSYTLNIEGANTHLDFRFSHLGPFKDA---TMLKIIVGDVDEPPLFSMPSYLMEV 392
E + +S + +E + L P + A + + V D ++PP F S+++
Sbjct: 346 ETRPAQSLIIVVENEERLVFCERGKLQPPRKAAASATVSVQVTDANDPPAFHPQSFIVNK 405
Query: 393 YENAKIGTVVGTVLAQDPDSTNSLVRYFINYNVEDDRFFNIDANTGTIRTTKVLDRE--- 449
E A+ GT++GT A DPDS +RY + + + + ++D N+G + T + +DRE
Sbjct: 406 EEGARPGTLLGTFNAMDPDSQ---IRYELVH--DPANWVSVDKNSGVVITVEPIDRESPH 460
Query: 450 -ETPWYNITVTASEIDNPDLLSHVTVGIRVLDVNDNPPEL-AREYDIIVCENSKPGQVIH 507
+Y I + A + P + T+ + + D+NDN P L R + VCE S + +H
Sbjct: 461 VNNSFYVIIIHAVDDGFPPQTATGTLMLFLSDINDNVPTLRPRSRYMEVCE-SAVHEPLH 519
Query: 508 TISATDKDDFANGPRFNFFLDERL-PVNPNFTLKDNEDNTASILTRRRRFSRTVQDVYYL 566
I A D D F F LD + L N + +LT R + Y +
Sbjct: 520 -IEAEDPDLEPFSDPFTFELDNTWGNAEDTWKLGRNWGQSVELLTLR----SLPRGNYLV 574
Query: 567 PIMISDGGIPSLSSSSTLTIRVCACERDGRVRTCHAEAFLSSAGLSTGALIAILLCVLIL 626
P+ I D LS T+ +R+C C TC E + GL GAL + +
Sbjct: 575 PLFIGDK--QGLSQKQTVHVRICPCASG---LTC-VELADAEVGLHVGALFPV-CAAFVA 627
Query: 627 LAIVVLFIT----LRRSKKEPLIISEEDVRENVVTYDDEGGGEEDTEAFDITALR----- 677
LA+ +LF+ + K+ +S ++ + +V Y+ E G D+ R
Sbjct: 628 LAVALLFLLRCYFVLEPKRHGCSVSNDEGHQTLVMYNAESKGTSAQTWSDVEGQRPALLI 687
Query: 678 -----------------NPSAAEELK----------YRRDIRP----EVKLTPRHQTSST 706
PSAA + Y + P + TP + ++
Sbjct: 688 CTAAAGPTQGVKDLEEVPPSAASQSAQARCALGSWGYGKPFEPRSVKNIHSTPAYPDATM 747
Query: 707 LESI------DVQEFIKQRLAEADL---DPSVPPYDSLQTYAYEGQRSEAGSISSLDSAT 757
+ + E + Q+L A++ DP P+ Y+ EG+ A S+SSL S
Sbjct: 748 HRQLLAPVEGRMAETLNQKLHVANVLEDDPGYLPH----VYSEEGECGGAPSLSSLASLE 803
Query: 758 TQSDQDYHYLGDWGPEFKKLAELYGE 783
+ D L G + E+Y E
Sbjct: 804 QELQPD--LLDSLGSKATPFEEIYSE 827
>gi|221316595 cadherin 17 precursor [Homo sapiens]
Length = 832
Score = 218 bits (556), Expect = 1e-56
Identities = 176/556 (31%), Positives = 262/556 (47%), Gaps = 48/556 (8%)
Query: 105 DTTGDIHSTKSLDREQKTHYVLHAQAIDRRTNKPLEPESEFIIKVQDINDNAPKFTDGPY 164
D GDI+ T+ LDRE+K YV +A A D KPL E +KV+DINDN P
Sbjct: 287 DQEGDIYVTQPLDREEKDAYVFYAVAKDEY-GKPLSYPLEIHVKVKDINDNPPTCPSPVT 345
Query: 165 IVTVPEMSDMGTSVLQVTATDADDPTYGNSARVVYSILQGQP------YFSVDPKTGVIR 218
+ V E +G S+ +TA D D+ NS + Y I++ P F + G+++
Sbjct: 346 VFEVQENERLGNSIGTLTAHDRDEENTANSF-LNYRIVEQTPKLPMDGLFLIQTYAGMLQ 404
Query: 219 TALHNMDREAREHYSVVIQAKDMAGQVGGLSGSTTVNITLTDVNDNPPRFPQKHY-QLYV 277
A ++ ++ Y++ I+ D V I + D+ND P F + Y L +
Sbjct: 405 LAKQSLKKQDTPQYNLTIEVSDK-----DFKTLCFVQINVIDINDQIPIFEKSDYGNLTL 459
Query: 278 PESAQVGSAVGKIKANDAD---TGSNADMTYSIINGDGMGIFSISTDKETREGILSLKKP 334
E +GS + I+A DAD TGS+ + Y II GD G + TD T G + +KKP
Sbjct: 460 AEDTNIGSTILTIQATDADEPFTGSSK-ILYHIIKGDSEGRLGVDTDPHTNTGYVIIKKP 518
Query: 335 LNYEKKKSYTLNIEGANTH-----LDFRFSHLGPFKDATMLKIIVGDVDEPPLFSMPSYL 389
L++E + + N + + S F +IV DV+E P FS +
Sbjct: 519 LDFETAAVSNIVFKAENPEPLVFGVKYNASSFAKFT------LIVTDVNEAPQFSQHVFQ 572
Query: 390 MEVYENAKIGTVVGTVLAQDPDSTNSLVRYFINYNVEDDR--FFNIDANTGTIRTTKVLD 447
+V E+ IGT VG V A+DP+ + I+Y++ D + ID TG I + LD
Sbjct: 573 AKVSEDVAIGTKVGNVTAKDPEGLD------ISYSLRGDTRGWLKIDHVTGEIFSVAPLD 626
Query: 448 REETPWYNITVTASEIDNPDLLSHVTVGIRVLDVNDNPPELAREYD-IIVCEN-SKPGQV 505
RE Y + V A+E+ L S + ++DVNDNPP LA++Y + C S PG +
Sbjct: 627 REAGSPYRVQVVATEVGGSSLSSVSEFHLILMDVNDNPPRLAKDYTGLFFCHPLSAPGSL 686
Query: 506 IHTISATDKDDFA-NGPRFNFFLDERLPVNPNFTLKDNEDNTASILTRRRRFSRTVQDVY 564
I ATD D GP F F L N K N + A + TR F + Y
Sbjct: 687 I--FEATDDDQHLFRGPHFTFSLGSGSLQNDWEVSKINGTH-ARLSTRHTEFE---EREY 740
Query: 565 YLPIMISDGGIPSLSSSSTLTIRVCACERDGRVRTCHAEAFLSSAGLSTGALIAILLCVL 624
+ I I+DGG P L +L + C+C R + + + G++ G L+ LL +
Sbjct: 741 VVLIRINDGGRPPLEGIVSLPVTFCSCVEGSCFRPAGHQTGIPTVGMAVGILLTTLLVIG 800
Query: 625 ILLAIVVLFITLRRSK 640
I+LA+V FI +++ K
Sbjct: 801 IILAVV--FIRIKKDK 814
Score = 145 bits (367), Expect = 1e-34
Identities = 130/451 (28%), Positives = 213/451 (47%), Gaps = 49/451 (10%)
Query: 87 SVKYILTGEGAGTIFIIDDTTGDIHSTKSLDREQKTHYVLHAQAIDRRTNKPLEPESEFI 146
+V + LTGE IF+I+ G ++ ++LDRE ++ + L A+D +E
Sbjct: 57 AVTFELTGE-TDNIFVIE-REGLLYYNRALDRETRSTHNLQVAALDAN-GIIVEGPVPIT 113
Query: 147 IKVQDINDNAPKFTDGPYIVTVPEMSDMGTSVLQVTATDADDPTYGNSARVVYSILQGQP 206
IKV+DINDN P F Y +V + S G L V ATD DDP N ++ Y I+ P
Sbjct: 114 IKVKDINDNRPTFLQSKYEGSVRQNSRPGKPFLYVNATDLDDPATPN-GQLYYQIVIQLP 172
Query: 207 ------YFSVDPKTGVI---RTALHNMDREAREHYSVVIQAKDMAGQ-VGGLSGSTTVNI 256
YF ++ KTG I R ++ Y++VI KDM GQ S +T+V+I
Sbjct: 173 MINNVMYFQINNKTGAISLTREGSQELNPAKNPSYNLVISVKDMGGQSENSFSDTTSVDI 232
Query: 257 TLTDVNDNPPRFPQKHYQLYVPESAQVGSAVGKIKANDADTGSNADMTYSIINGDGMGIF 316
+T+ P K ++ + + +++ ND YS+++ + + F
Sbjct: 233 IVTENIWKAP----KPVEMVENSTDPHPIKITQVRWNDPGA------QYSLVDKEKLPRF 282
Query: 317 SISTDKETREGILSLKKPLNYEKKKSYTLNIEGANTHLDFRFSHLGPFKDATMLKIIVGD 376
S D +EG + + +PL+ E+K +Y + + + P + + V D
Sbjct: 283 PFSID---QEGDIYVTQPLDREEKDAYVF-------YAVAKDEYGKPLSYPLEIHVKVKD 332
Query: 377 V-DEPPLFSMPSYLMEVYENAKIGTVVGTVLAQDPDSTNSLVRYFINYNVED-------D 428
+ D PP P + EV EN ++G +GT+ A D D N+ F+NY + + D
Sbjct: 333 INDNPPTCPSPVTVFEVQENERLGNSIGTLTAHDRDEENT-ANSFLNYRIVEQTPKLPMD 391
Query: 429 RFFNIDANTGTIRTTK-VLDREETPWYNITVTASEIDNPDLLSHVTVGIRVLDVNDNPP- 486
F I G ++ K L +++TP YN+T+ E+ + D + V I V+D+ND P
Sbjct: 392 GLFLIQTYAGMLQLAKQSLKKQDTPQYNLTI---EVSDKDFKTLCFVQINVIDINDQIPI 448
Query: 487 -ELAREYDIIVCENSKPGQVIHTISATDKDD 516
E + ++ + E++ G I TI ATD D+
Sbjct: 449 FEKSDYGNLTLAEDTNIGSTILTIQATDADE 479
Score = 42.4 bits (98), Expect = 0.002
Identities = 59/205 (28%), Positives = 88/205 (42%), Gaps = 16/205 (7%)
Query: 88 VKYILTGEGAGTIFIIDDTTGDIHSTKSLDREQKTHYVLHAQAIDRRTNKPLEPESEFII 147
+ Y L G+ G + I D TG+I S LDRE + Y + A + L SEF +
Sbjct: 598 ISYSLRGDTRGWLKI-DHVTGEIFSVAPLDREAGSPYRVQVVATE-VGGSSLSSVSEFHL 655
Query: 148 KVQDINDNAPKFT-DGPYIVTVPEMSDMGTSVLQVTATDADDPTYGNSARVVYSILQG-- 204
+ D+NDN P+ D + +S G+ + + ATD DD +S+ G
Sbjct: 656 ILMDVNDNPPRLAKDYTGLFFCHPLSAPGSLIFE--ATD-DDQHLFRGPHFTFSLGSGSL 712
Query: 205 QPYFSVDPKTGV-IRTALHNMDREAREHYSVVIQAKDMAGQVGGLSGSTTVNITLTDVND 263
Q + V G R + + + E RE Y V+I+ D G L G ++ +T +
Sbjct: 713 QNDWEVSKINGTHARLSTRHTEFEERE-YVVLIRIND--GGRPPLEGIVSLPVTFCSCVE 769
Query: 264 NPPRFPQKHYQLYVPESAQVGSAVG 288
P H Q +P VG AVG
Sbjct: 770 GSCFRPAGH-QTGIP---TVGMAVG 790
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.316 0.134 0.388
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 29,997,707
Number of Sequences: 37866
Number of extensions: 1371639
Number of successful extensions: 8898
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 196
Number of HSP's successfully gapped in prelim test: 18
Number of HSP's that attempted gapping in prelim test: 3226
Number of HSP's gapped (non-prelim): 849
length of query: 790
length of database: 18,247,518
effective HSP length: 110
effective length of query: 680
effective length of database: 14,082,258
effective search space: 9575935440
effective search space used: 9575935440
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.