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Search of human proteins with 47519616
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|47519616 tropomyosin 2 (beta) isoform 2 [Homo sapiens]
(284 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|47519616 tropomyosin 2 (beta) isoform 2 [Homo sapiens] 531 e-151
gi|42476296 tropomyosin 2 (beta) isoform 1 [Homo sapiens] 461 e-130
gi|63252900 tropomyosin 1 alpha chain isoform 4 [Homo sapiens] 455 e-128
gi|223555975 tropomyosin 4 isoform 1 [Homo sapiens] 449 e-126
gi|63252896 tropomyosin 1 alpha chain isoform 3 [Homo sapiens] 444 e-125
gi|27597085 tropomyosin 1 alpha chain isoform 5 [Homo sapiens] 426 e-120
gi|114155140 tropomyosin 3 isoform 1 [Homo sapiens] 418 e-117
gi|63252906 tropomyosin 1 alpha chain isoform 7 [Homo sapiens] 417 e-117
gi|63252898 tropomyosin 1 alpha chain isoform 1 [Homo sapiens] 416 e-116
gi|63252902 tropomyosin 1 alpha chain isoform 2 [Homo sapiens] 407 e-114
gi|224922812 tropomyosin 2 (beta) isoform 3 [Homo sapiens] 347 9e-96
gi|4507651 tropomyosin 4 isoform 2 [Homo sapiens] 334 5e-92
gi|24119203 tropomyosin 3 isoform 2 [Homo sapiens] 327 7e-90
gi|114155144 tropomyosin 3 isoform 4 [Homo sapiens] 319 2e-87
gi|114155146 tropomyosin 3 isoform 3 [Homo sapiens] 315 4e-86
gi|114155148 tropomyosin 3 isoform 5 [Homo sapiens] 307 8e-84
gi|63252904 tropomyosin 1 alpha chain isoform 6 [Homo sapiens] 298 5e-81
gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo sap... 94 1e-19
gi|239745153 PREDICTED: similar to Putative golgin subfamily A m... 94 2e-19
gi|239745127 PREDICTED: similar to Putative golgin subfamily A m... 94 2e-19
gi|62243484 sarcoma antigen NY-SAR-41 [Homo sapiens] 87 2e-17
gi|12667788 myosin, heavy polypeptide 9, non-muscle [Homo sapiens] 86 5e-17
gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo sa... 85 6e-17
gi|239745299 PREDICTED: hypothetical protein [Homo sapiens] 85 8e-17
gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo sa... 84 1e-16
gi|239745079 PREDICTED: Putative golgin subfamily A member 6-lik... 84 1e-16
gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-li... 82 5e-16
gi|115496169 myosin, heavy chain 7, cardiac muscle, beta [Homo s... 81 9e-16
gi|153945790 myosin, heavy chain 8, skeletal muscle, perinatal [... 81 9e-16
gi|31982906 cingulin-like 1 [Homo sapiens] 80 2e-15
>gi|47519616 tropomyosin 2 (beta) isoform 2 [Homo sapiens]
Length = 284
Score = 531 bits (1369), Expect = e-151
Identities = 284/284 (100%), Positives = 284/284 (100%)
Query: 1 MDAIKKKMQMLKLDKENAIDRAEQAEADKKQAEDRCKQLEEEQQALQKKLKGTEDEVEKY 60
MDAIKKKMQMLKLDKENAIDRAEQAEADKKQAEDRCKQLEEEQQALQKKLKGTEDEVEKY
Sbjct: 1 MDAIKKKMQMLKLDKENAIDRAEQAEADKKQAEDRCKQLEEEQQALQKKLKGTEDEVEKY 60
Query: 61 SESVKEAQEKLEQAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAA 120
SESVKEAQEKLEQAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAA
Sbjct: 61 SESVKEAQEKLEQAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAA 120
Query: 121 DESERGMKVIENRAMKDEEKMELQEMQLKEAKHIAEDSDRKYEEVARKLVILEGELERSE 180
DESERGMKVIENRAMKDEEKMELQEMQLKEAKHIAEDSDRKYEEVARKLVILEGELERSE
Sbjct: 121 DESERGMKVIENRAMKDEEKMELQEMQLKEAKHIAEDSDRKYEEVARKLVILEGELERSE 180
Query: 181 ERAEVAESRARQLEEELRTMDQALKSLMASEEEYSTKEDKYEEEIKLLEEKLKEAETRAE 240
ERAEVAESRARQLEEELRTMDQALKSLMASEEEYSTKEDKYEEEIKLLEEKLKEAETRAE
Sbjct: 181 ERAEVAESRARQLEEELRTMDQALKSLMASEEEYSTKEDKYEEEIKLLEEKLKEAETRAE 240
Query: 241 FAERSVAKLEKTIDDLEETLASAKEENVEIHQTLDQTLLELNNL 284
FAERSVAKLEKTIDDLEETLASAKEENVEIHQTLDQTLLELNNL
Sbjct: 241 FAERSVAKLEKTIDDLEETLASAKEENVEIHQTLDQTLLELNNL 284
>gi|42476296 tropomyosin 2 (beta) isoform 1 [Homo sapiens]
Length = 284
Score = 461 bits (1187), Expect = e-130
Identities = 248/284 (87%), Positives = 261/284 (91%)
Query: 1 MDAIKKKMQMLKLDKENAIDRAEQAEADKKQAEDRCKQLEEEQQALQKKLKGTEDEVEKY 60
MDAIKKKMQMLKLDKENAIDRAEQAEADKKQAEDRCKQLEEEQQALQKKLKGTEDEVEKY
Sbjct: 1 MDAIKKKMQMLKLDKENAIDRAEQAEADKKQAEDRCKQLEEEQQALQKKLKGTEDEVEKY 60
Query: 61 SESVKEAQEKLEQAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAA 120
SESVKEAQEKLEQAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAA
Sbjct: 61 SESVKEAQEKLEQAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAA 120
Query: 121 DESERGMKVIENRAMKDEEKMELQEMQLKEAKHIAEDSDRKYEEVARKLVILEGELERSE 180
DESERGMKVIENRAMKDEEKMELQEMQLKEAKHIAEDSDRKYEEVARKLVILEGELERSE
Sbjct: 121 DESERGMKVIENRAMKDEEKMELQEMQLKEAKHIAEDSDRKYEEVARKLVILEGELERSE 180
Query: 181 ERAEVAESRARQLEEELRTMDQALKSLMASEEEYSTKEDKYEEEIKLLEEKLKEAETRAE 240
ERAEVAES+ LEEEL+ + LKSL A ++YSTKEDKYEEEIKLLEEKLKEAETRAE
Sbjct: 181 ERAEVAESKCGDLEEELKIVTNNLKSLEAQADKYSTKEDKYEEEIKLLEEKLKEAETRAE 240
Query: 241 FAERSVAKLEKTIDDLEETLASAKEENVEIHQTLDQTLLELNNL 284
FAERSVAKLEKTIDDLE+ + + K + I + LD L ++ +L
Sbjct: 241 FAERSVAKLEKTIDDLEDEVYAQKMKYKAISEELDNALNDITSL 284
>gi|63252900 tropomyosin 1 alpha chain isoform 4 [Homo sapiens]
Length = 284
Score = 455 bits (1171), Expect = e-128
Identities = 235/284 (82%), Positives = 266/284 (93%)
Query: 1 MDAIKKKMQMLKLDKENAIDRAEQAEADKKQAEDRCKQLEEEQQALQKKLKGTEDEVEKY 60
MDAIKKKMQMLKLDKENA+DRAEQAEADKK AEDR KQLE+E +LQKKLKGTEDE++KY
Sbjct: 1 MDAIKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTEDELDKY 60
Query: 61 SESVKEAQEKLEQAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAA 120
SE++K+AQEKLE AEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAA
Sbjct: 61 SEALKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAA 120
Query: 121 DESERGMKVIENRAMKDEEKMELQEMQLKEAKHIAEDSDRKYEEVARKLVILEGELERSE 180
DESERGMKVIE+RA KDEEKME+QE+QLKEAKHIAED+DRKYEEVARKLVI+E +LER+E
Sbjct: 121 DESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAE 180
Query: 181 ERAEVAESRARQLEEELRTMDQALKSLMASEEEYSTKEDKYEEEIKLLEEKLKEAETRAE 240
ERAE++E + RQLEE+LR MDQ LK+LMA+E++YS KED+YEEEIK+L +KLKEAETRAE
Sbjct: 181 ERAELSEGQVRQLEEQLRIMDQTLKALMAAEDKYSQKEDRYEEEIKVLSDKLKEAETRAE 240
Query: 241 FAERSVAKLEKTIDDLEETLASAKEENVEIHQTLDQTLLELNNL 284
FAERSV KLEK+IDDLEE +A AKEEN+ +HQ LDQTLLELNN+
Sbjct: 241 FAERSVTKLEKSIDDLEEKVAHAKEENLSMHQMLDQTLLELNNM 284
>gi|223555975 tropomyosin 4 isoform 1 [Homo sapiens]
Length = 284
Score = 449 bits (1154), Expect = e-126
Identities = 236/282 (83%), Positives = 258/282 (91%)
Query: 1 MDAIKKKMQMLKLDKENAIDRAEQAEADKKQAEDRCKQLEEEQQALQKKLKGTEDEVEKY 60
M+AIKKKMQMLKLDKENAIDRAEQAEADKK AED+CKQ+EEE LQKKLKGTEDE++KY
Sbjct: 1 MEAIKKKMQMLKLDKENAIDRAEQAEADKKAAEDKCKQVEEELTHLQKKLKGTEDELDKY 60
Query: 61 SESVKEAQEKLEQAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAA 120
SE +K+AQEKLE EKKA+DAE DVA+LNRRIQLVEEELDRAQERLATALQKLEEAEKAA
Sbjct: 61 SEDLKDAQEKLELTEKKASDAEGDVAALNRRIQLVEEELDRAQERLATALQKLEEAEKAA 120
Query: 121 DESERGMKVIENRAMKDEEKMELQEMQLKEAKHIAEDSDRKYEEVARKLVILEGELERSE 180
DESERGMKVIENRAMKDEEKME+QEMQLKEAKHIAE++DRKYEEVARKLVILEGELER+E
Sbjct: 121 DESERGMKVIENRAMKDEEKMEIQEMQLKEAKHIAEEADRKYEEVARKLVILEGELERAE 180
Query: 181 ERAEVAESRARQLEEELRTMDQALKSLMASEEEYSTKEDKYEEEIKLLEEKLKEAETRAE 240
ERAEV+E + LEEEL+ + LKSL A+ E+YS KEDKYEEEIKLL +KLKEAETRAE
Sbjct: 181 ERAEVSELKCGDLEEELKNVTNNLKSLEAASEKYSEKEDKYEEEIKLLSDKLKEAETRAE 240
Query: 241 FAERSVAKLEKTIDDLEETLASAKEENVEIHQTLDQTLLELN 282
FAER+VAKLEKTIDDLEE LA AKEENV +HQTLDQTL ELN
Sbjct: 241 FAERTVAKLEKTIDDLEEKLAQAKEENVGLHQTLDQTLNELN 282
>gi|63252896 tropomyosin 1 alpha chain isoform 3 [Homo sapiens]
Length = 284
Score = 444 bits (1143), Expect = e-125
Identities = 231/284 (81%), Positives = 261/284 (91%)
Query: 1 MDAIKKKMQMLKLDKENAIDRAEQAEADKKQAEDRCKQLEEEQQALQKKLKGTEDEVEKY 60
MDAIKKKMQMLKLDKENA+DRAEQAEADKK AEDR KQLE+E +LQKKLKGTEDE++KY
Sbjct: 1 MDAIKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTEDELDKY 60
Query: 61 SESVKEAQEKLEQAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAA 120
SE++K+AQEKLE AEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAA
Sbjct: 61 SEALKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAA 120
Query: 121 DESERGMKVIENRAMKDEEKMELQEMQLKEAKHIAEDSDRKYEEVARKLVILEGELERSE 180
DESERGMKVIE+RA KDEEKME+QE+QLKEAKHIAED+DRKYEEVARKLVI+E +LER+E
Sbjct: 121 DESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAE 180
Query: 181 ERAEVAESRARQLEEELRTMDQALKSLMASEEEYSTKEDKYEEEIKLLEEKLKEAETRAE 240
ERAE++E + +LEEEL+T+ LKSL A E+YS KED+YEEEIK+L +KLKEAETRAE
Sbjct: 181 ERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKEDRYEEEIKVLSDKLKEAETRAE 240
Query: 241 FAERSVAKLEKTIDDLEETLASAKEENVEIHQTLDQTLLELNNL 284
FAERSV KLEK+IDDLEE +A AKEEN+ +HQ LDQTLLELNN+
Sbjct: 241 FAERSVTKLEKSIDDLEEKVAHAKEENLSMHQMLDQTLLELNNM 284
>gi|27597085 tropomyosin 1 alpha chain isoform 5 [Homo sapiens]
Length = 284
Score = 426 bits (1096), Expect = e-120
Identities = 222/284 (78%), Positives = 257/284 (90%)
Query: 1 MDAIKKKMQMLKLDKENAIDRAEQAEADKKQAEDRCKQLEEEQQALQKKLKGTEDEVEKY 60
MDAIKKKMQMLKLDKENA+DRAEQAEADKK AEDR KQLE+E +LQKKLKGTEDE++KY
Sbjct: 1 MDAIKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTEDELDKY 60
Query: 61 SESVKEAQEKLEQAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAA 120
SE++K+AQEKLE AEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAA
Sbjct: 61 SEALKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAA 120
Query: 121 DESERGMKVIENRAMKDEEKMELQEMQLKEAKHIAEDSDRKYEEVARKLVILEGELERSE 180
DESERGMKVIE+RA KDEEKME+QE+QLKEAKHIAED+DRKYEEVARKLVI+E +LER+E
Sbjct: 121 DESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAE 180
Query: 181 ERAEVAESRARQLEEELRTMDQALKSLMASEEEYSTKEDKYEEEIKLLEEKLKEAETRAE 240
ERAE++E + RQLEE+LR MDQ LK+LMA+E++YS KED+YEEEIK+L +KLKEAETRAE
Sbjct: 181 ERAELSEGQVRQLEEQLRIMDQTLKALMAAEDKYSQKEDRYEEEIKVLSDKLKEAETRAE 240
Query: 241 FAERSVAKLEKTIDDLEETLASAKEENVEIHQTLDQTLLELNNL 284
FAERSV KLEK+IDDLE+ L + K + I + LD L ++ ++
Sbjct: 241 FAERSVTKLEKSIDDLEDELYAQKLKYKAISEELDHALNDMTSM 284
>gi|114155140 tropomyosin 3 isoform 1 [Homo sapiens]
Length = 285
Score = 418 bits (1075), Expect = e-117
Identities = 219/284 (77%), Positives = 255/284 (89%)
Query: 1 MDAIKKKMQMLKLDKENAIDRAEQAEADKKQAEDRCKQLEEEQQALQKKLKGTEDEVEKY 60
M+AIKKKMQMLKLDKENA+DRAEQAEA++KQAE+R KQLE+E A+QKKLKGTEDE++KY
Sbjct: 2 MEAIKKKMQMLKLDKENALDRAEQAEAEQKQAEERSKQLEDELAAMQKKLKGTEDELDKY 61
Query: 61 SESVKEAQEKLEQAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAA 120
SE++K+AQEKLE AEKKA DAEA+VASLNRRIQLVEEELDRAQERLATALQKLEEAEKAA
Sbjct: 62 SEALKDAQEKLELAEKKAADAEAEVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAA 121
Query: 121 DESERGMKVIENRAMKDEEKMELQEMQLKEAKHIAEDSDRKYEEVARKLVILEGELERSE 180
DESERGMKVIENRA+KDEEKMELQE+QLKEAKHIAE++DRKYEEVARKLVI+EG+LER+E
Sbjct: 122 DESERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKYEEVARKLVIIEGDLERTE 181
Query: 181 ERAEVAESRARQLEEELRTMDQALKSLMASEEEYSTKEDKYEEEIKLLEEKLKEAETRAE 240
ERAE+AES+ +LEEEL+ + LKSL A E+YS KEDKYEEEIK+L +KLKEAETRAE
Sbjct: 182 ERAELAESKCSELEEELKNVTNNLKSLEAQAEKYSQKEDKYEEEIKILTDKLKEAETRAE 241
Query: 241 FAERSVAKLEKTIDDLEETLASAKEENVEIHQTLDQTLLELNNL 284
FAERSVAKLEKTIDDLE+ L + K + I + LD L ++ ++
Sbjct: 242 FAERSVAKLEKTIDDLEDELYAQKLKYKAISEELDHALNDMTSI 285
>gi|63252906 tropomyosin 1 alpha chain isoform 7 [Homo sapiens]
Length = 284
Score = 417 bits (1073), Expect = e-117
Identities = 218/284 (76%), Positives = 253/284 (89%)
Query: 1 MDAIKKKMQMLKLDKENAIDRAEQAEADKKQAEDRCKQLEEEQQALQKKLKGTEDEVEKY 60
MDAIKKKMQMLKLDKENA+DRAEQAEADKK AEDR KQLEE+ A +K L+ +EDE ++
Sbjct: 1 MDAIKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEEDIAAKEKLLRVSEDERDRV 60
Query: 61 SESVKEAQEKLEQAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAA 120
E + +A++ L AE+ A AEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAA
Sbjct: 61 LEELHKAEDSLLAAEEAAAKAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAA 120
Query: 121 DESERGMKVIENRAMKDEEKMELQEMQLKEAKHIAEDSDRKYEEVARKLVILEGELERSE 180
DESERGMKVIE+RA KDEEKME+QE+QLKEAKHIAED+DRKYEEVARKLVI+E +LER+E
Sbjct: 121 DESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAE 180
Query: 181 ERAEVAESRARQLEEELRTMDQALKSLMASEEEYSTKEDKYEEEIKLLEEKLKEAETRAE 240
ERAE++E + RQLEE+LR MDQ LK+LMA+E++YS KED+YEEEIK+L +KLKEAETRAE
Sbjct: 181 ERAELSEGQVRQLEEQLRIMDQTLKALMAAEDKYSQKEDRYEEEIKVLSDKLKEAETRAE 240
Query: 241 FAERSVAKLEKTIDDLEETLASAKEENVEIHQTLDQTLLELNNL 284
FAERSV KLEK+IDDLEE +A AKEEN+ +HQ LDQTLLELNN+
Sbjct: 241 FAERSVTKLEKSIDDLEEKVAHAKEENLSMHQMLDQTLLELNNM 284
>gi|63252898 tropomyosin 1 alpha chain isoform 1 [Homo sapiens]
Length = 284
Score = 416 bits (1068), Expect = e-116
Identities = 218/284 (76%), Positives = 252/284 (88%)
Query: 1 MDAIKKKMQMLKLDKENAIDRAEQAEADKKQAEDRCKQLEEEQQALQKKLKGTEDEVEKY 60
MDAIKKKMQMLKLDKENA+DRAEQAEADKK AEDR KQLE+E +LQKKLKGTEDE++KY
Sbjct: 1 MDAIKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTEDELDKY 60
Query: 61 SESVKEAQEKLEQAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAA 120
SE++K+AQEKLE AEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAA
Sbjct: 61 SEALKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAA 120
Query: 121 DESERGMKVIENRAMKDEEKMELQEMQLKEAKHIAEDSDRKYEEVARKLVILEGELERSE 180
DESERGMKVIE+RA KDEEKME+QE+QLKEAKHIAED+DRKYEEVARKLVI+E +LER+E
Sbjct: 121 DESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAE 180
Query: 181 ERAEVAESRARQLEEELRTMDQALKSLMASEEEYSTKEDKYEEEIKLLEEKLKEAETRAE 240
ERAE++E + +LEEEL+T+ LKSL A E+YS KED+YEEEIK+L +KLKEAETRAE
Sbjct: 181 ERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKEDRYEEEIKVLSDKLKEAETRAE 240
Query: 241 FAERSVAKLEKTIDDLEETLASAKEENVEIHQTLDQTLLELNNL 284
FAERSV KLEK+IDDLE+ L + K + I + LD L ++ ++
Sbjct: 241 FAERSVTKLEKSIDDLEDELYAQKLKYKAISEELDHALNDMTSI 284
>gi|63252902 tropomyosin 1 alpha chain isoform 2 [Homo sapiens]
Length = 284
Score = 407 bits (1045), Expect = e-114
Identities = 214/284 (75%), Positives = 248/284 (87%)
Query: 1 MDAIKKKMQMLKLDKENAIDRAEQAEADKKQAEDRCKQLEEEQQALQKKLKGTEDEVEKY 60
MDAIKKKMQMLKLDKENA+DRAEQAEADKK AEDR KQLEE+ A +K L+ +EDE ++
Sbjct: 1 MDAIKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEEDIAAKEKLLRVSEDERDRV 60
Query: 61 SESVKEAQEKLEQAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAA 120
E + +A++ L AE+ A AEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAA
Sbjct: 61 LEELHKAEDSLLAAEEAAAKAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAA 120
Query: 121 DESERGMKVIENRAMKDEEKMELQEMQLKEAKHIAEDSDRKYEEVARKLVILEGELERSE 180
DESERGMKVIE+RA KDEEKME+QE+QLKEAKHIAED+DRKYEEVARKLVI+E +LER+E
Sbjct: 121 DESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAE 180
Query: 181 ERAEVAESRARQLEEELRTMDQALKSLMASEEEYSTKEDKYEEEIKLLEEKLKEAETRAE 240
ERAE++E + +LEEEL+T+ LKSL A E+YS KED+YEEEIK+L +KLKEAETRAE
Sbjct: 181 ERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKEDRYEEEIKVLSDKLKEAETRAE 240
Query: 241 FAERSVAKLEKTIDDLEETLASAKEENVEIHQTLDQTLLELNNL 284
FAERSV KLEK+IDDLEE +A AKEEN+ +HQ LDQTLLELNN+
Sbjct: 241 FAERSVTKLEKSIDDLEEKVAHAKEENLSMHQMLDQTLLELNNM 284
>gi|224922812 tropomyosin 2 (beta) isoform 3 [Homo sapiens]
Length = 231
Score = 347 bits (889), Expect = 9e-96
Identities = 200/284 (70%), Positives = 215/284 (75%), Gaps = 53/284 (18%)
Query: 1 MDAIKKKMQMLKLDKENAIDRAEQAEADKKQAEDRCKQLEEEQQALQKKLKGTEDEVEKY 60
MDAIKKKMQMLKLDKENAI DR +Q E +++
Sbjct: 1 MDAIKKKMQMLKLDKENAI--------------DRAEQAEADKK---------------- 30
Query: 61 SESVKEAQEKLEQAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAA 120
QAE + E + +L ++++ E+E++ K E+EKAA
Sbjct: 31 ------------QAEDRCKQLEEEQQALQKKLKGTEDEVE-----------KYSESEKAA 67
Query: 121 DESERGMKVIENRAMKDEEKMELQEMQLKEAKHIAEDSDRKYEEVARKLVILEGELERSE 180
DESERGMKVIENRAMKDEEKMELQEMQLKEAKHIAEDSDRKYEEVARKLVILEGELERSE
Sbjct: 68 DESERGMKVIENRAMKDEEKMELQEMQLKEAKHIAEDSDRKYEEVARKLVILEGELERSE 127
Query: 181 ERAEVAESRARQLEEELRTMDQALKSLMASEEEYSTKEDKYEEEIKLLEEKLKEAETRAE 240
ERAEVAESRARQLEEELRTMDQALKSLMASEEEYSTKEDKYEEEIKLLEEKLKEAETRAE
Sbjct: 128 ERAEVAESRARQLEEELRTMDQALKSLMASEEEYSTKEDKYEEEIKLLEEKLKEAETRAE 187
Query: 241 FAERSVAKLEKTIDDLEETLASAKEENVEIHQTLDQTLLELNNL 284
FAERSVAKLEKTIDDLEETLASAKEENVEIHQTLDQTLLELNNL
Sbjct: 188 FAERSVAKLEKTIDDLEETLASAKEENVEIHQTLDQTLLELNNL 231
>gi|4507651 tropomyosin 4 isoform 2 [Homo sapiens]
Length = 248
Score = 334 bits (857), Expect = 5e-92
Identities = 175/239 (73%), Positives = 205/239 (85%)
Query: 44 QALQKKLKGTEDEVEKYSESVKEAQEKLEQAEKKATDAEADVASLNRRIQLVEEELDRAQ 103
+A+++K++ + + ++ + + Q +L+ ++ AE DVA+LNRRIQLVEEELDRAQ
Sbjct: 8 EAVKRKIQALQQQADEAEDRAQGLQRELDGERERREKAEGDVAALNRRIQLVEEELDRAQ 67
Query: 104 ERLATALQKLEEAEKAADESERGMKVIENRAMKDEEKMELQEMQLKEAKHIAEDSDRKYE 163
ERLATALQKLEEAEKAADESERGMKVIENRAMKDEEKME+QEMQLKEAKHIAE++DRKYE
Sbjct: 68 ERLATALQKLEEAEKAADESERGMKVIENRAMKDEEKMEIQEMQLKEAKHIAEEADRKYE 127
Query: 164 EVARKLVILEGELERSEERAEVAESRARQLEEELRTMDQALKSLMASEEEYSTKEDKYEE 223
EVARKLVILEGELER+EERAEV+E + LEEEL+ + LKSL A+ E+YS KEDKYEE
Sbjct: 128 EVARKLVILEGELERAEERAEVSELKCGDLEEELKNVTNNLKSLEAASEKYSEKEDKYEE 187
Query: 224 EIKLLEEKLKEAETRAEFAERSVAKLEKTIDDLEETLASAKEENVEIHQTLDQTLLELN 282
EIKLL +KLKEAETRAEFAER+VAKLEKTIDDLEE LA AKEENV +HQTLDQTL ELN
Sbjct: 188 EIKLLSDKLKEAETRAEFAERTVAKLEKTIDDLEEKLAQAKEENVGLHQTLDQTLNELN 246
Score = 57.0 bits (136), Expect = 2e-08
Identities = 33/114 (28%), Positives = 63/114 (55%)
Query: 2 DAIKKKMQMLKLDKENAIDRAEQAEADKKQAEDRCKQLEEEQQALQKKLKGTEDEVEKYS 61
+ + +K+ +L+ + E A +RAE +E E+ K + ++L+ + ++ +KY
Sbjct: 127 EEVARKLVILEGELERAEERAEVSELKCGDLEEELKNVTNNLKSLEAASEKYSEKEDKYE 186
Query: 62 ESVKEAQEKLEQAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEE 115
E +K +KL++AE +A AE VA L + I +EE+L +A+E Q L++
Sbjct: 187 EEIKLLSDKLKEAETRAEFAERTVAKLEKTIDDLEEKLAQAKEENVGLHQTLDQ 240
Score = 35.0 bits (79), Expect = 0.075
Identities = 20/90 (22%), Positives = 44/90 (48%)
Query: 11 LKLDKENAIDRAEQAEADKKQAEDRCKQLEEEQQALQKKLKGTEDEVEKYSESVKEAQEK 70
L+ + +N + + EA ++ ++ + EEE + L KLK E E +V + ++
Sbjct: 157 LEEELKNVTNNLKSLEAASEKYSEKEDKYEEEIKLLSDKLKEAETRAEFAERTVAKLEKT 216
Query: 71 LEQAEKKATDAEADVASLNRRIQLVEEELD 100
++ E+K A+ + L++ + EL+
Sbjct: 217 IDDLEEKLAQAKEENVGLHQTLDQTLNELN 246
>gi|24119203 tropomyosin 3 isoform 2 [Homo sapiens]
Length = 248
Score = 327 bits (838), Expect = 7e-90
Identities = 169/241 (70%), Positives = 206/241 (85%)
Query: 44 QALQKKLKGTEDEVEKYSESVKEAQEKLEQAEKKATDAEADVASLNRRIQLVEEELDRAQ 103
+A+++K++ + + + E + Q ++E + AEA+VASLNRRIQLVEEELDRAQ
Sbjct: 8 EAVKRKIQVLQQQADDAEERAERLQREVEGERRAREQAEAEVASLNRRIQLVEEELDRAQ 67
Query: 104 ERLATALQKLEEAEKAADESERGMKVIENRAMKDEEKMELQEMQLKEAKHIAEDSDRKYE 163
ERLATALQKLEEAEKAADESERGMKVIENRA+KDEEKMELQE+QLKEAKHIAE++DRKYE
Sbjct: 68 ERLATALQKLEEAEKAADESERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKYE 127
Query: 164 EVARKLVILEGELERSEERAEVAESRARQLEEELRTMDQALKSLMASEEEYSTKEDKYEE 223
EVARKLVI+EG+LER+EERAE+AESR R+++E++R MDQ LK L A+EE+YS KEDKYEE
Sbjct: 128 EVARKLVIIEGDLERTEERAELAESRCREMDEQIRLMDQNLKCLSAAEEKYSQKEDKYEE 187
Query: 224 EIKLLEEKLKEAETRAEFAERSVAKLEKTIDDLEETLASAKEENVEIHQTLDQTLLELNN 283
EIK+L +KLKEAETRAEFAERSVAKLEKTIDDLE+ L KEE++ + LDQTLL+LN
Sbjct: 188 EIKILTDKLKEAETRAEFAERSVAKLEKTIDDLEDKLKCTKEEHLCTQRMLDQTLLDLNE 247
Query: 284 L 284
+
Sbjct: 248 M 248
Score = 64.3 bits (155), Expect = 1e-10
Identities = 44/184 (23%), Positives = 93/184 (50%), Gaps = 16/184 (8%)
Query: 85 VASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIENRAMKDEEKMELQ 144
+ ++ R+IQ+++++ D A+ER +++E +A +++E + + R EE+++
Sbjct: 7 IEAVKRKIQVLQQQADDAEERAERLQREVEGERRAREQAEAEVASLNRRIQLVEEELDRA 66
Query: 145 EMQLKEAKHIAEDSDRKYEEVARKLVILEGELERSEERAEVAESRARQLEEELRTMDQAL 204
+ +L A E++++ +E SE +V E+RA + EE++ + L
Sbjct: 67 QERLATALQKLEEAEKAADE--------------SERGMKVIENRALKDEEKMELQEIQL 112
Query: 205 KSLMASEEEYSTKEDKYEEEIKLLEEKLKEAETRAEFAERSVAKLEKTIDDLEETL--AS 262
K EE K ++ ++ ++E L+ E RAE AE ++++ I +++ L S
Sbjct: 113 KEAKHIAEEADRKYEEVARKLVIIEGDLERTEERAELAESRCREMDEQIRLMDQNLKCLS 172
Query: 263 AKEE 266
A EE
Sbjct: 173 AAEE 176
Score = 40.8 bits (94), Expect = 0.001
Identities = 32/140 (22%), Positives = 67/140 (47%), Gaps = 6/140 (4%)
Query: 141 MELQEMQLKEAKHIAEDSDRKYEEVARKLVILEGELE-RSEERAEVAE--SRARQLEEEL 197
+E + +++ + A+D++ + E + R++ EGE R + AEVA R + +EEEL
Sbjct: 7 IEAVKRKIQVLQQQADDAEERAERLQREV---EGERRAREQAEAEVASLNRRIQLVEEEL 63
Query: 198 RTMDQALKSLMASEEEYSTKEDKYEEEIKLLEEKLKEAETRAEFAERSVAKLEKTIDDLE 257
+ L + + EE D+ E +K++E + + E + E E + + + ++ +
Sbjct: 64 DRAQERLATALQKLEEAEKAADESERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEAD 123
Query: 258 ETLASAKEENVEIHQTLDQT 277
+ V I L++T
Sbjct: 124 RKYEEVARKLVIIEGDLERT 143
>gi|114155144 tropomyosin 3 isoform 4 [Homo sapiens]
Length = 248
Score = 319 bits (818), Expect = 2e-87
Identities = 167/241 (69%), Positives = 202/241 (83%)
Query: 44 QALQKKLKGTEDEVEKYSESVKEAQEKLEQAEKKATDAEADVASLNRRIQLVEEELDRAQ 103
+A+++K++ + + + E + Q ++E + AEA+VASLNRRIQLVEEELDRAQ
Sbjct: 8 EAVKRKIQVLQQQADDAEERAERLQREVEGERRAREQAEAEVASLNRRIQLVEEELDRAQ 67
Query: 104 ERLATALQKLEEAEKAADESERGMKVIENRAMKDEEKMELQEMQLKEAKHIAEDSDRKYE 163
ERLATALQKLEEAEKAADESERGMKVIENRA+KDEEKMELQE+QLKEAKHIAE++DRKYE
Sbjct: 68 ERLATALQKLEEAEKAADESERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKYE 127
Query: 164 EVARKLVILEGELERSEERAEVAESRARQLEEELRTMDQALKSLMASEEEYSTKEDKYEE 223
EVARKLVI+EG+LER+EERAE+AES+ +LEEEL+ + LKSL A E+YS KEDKYEE
Sbjct: 128 EVARKLVIIEGDLERTEERAELAESKCSELEEELKNVTNNLKSLEAQAEKYSQKEDKYEE 187
Query: 224 EIKLLEEKLKEAETRAEFAERSVAKLEKTIDDLEETLASAKEENVEIHQTLDQTLLELNN 283
EIK+L +KLKEAETRAEFAERSVAKLEKTIDDLE+ L KEE++ + LDQTLL+LN
Sbjct: 188 EIKILTDKLKEAETRAEFAERSVAKLEKTIDDLEDKLKCTKEEHLCTQRMLDQTLLDLNE 247
Query: 284 L 284
+
Sbjct: 248 M 248
Score = 68.2 bits (165), Expect = 8e-12
Identities = 44/192 (22%), Positives = 96/192 (50%), Gaps = 14/192 (7%)
Query: 85 VASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIENRAMKDEEKMELQ 144
+ ++ R+IQ+++++ D A+ER +++E +A +++E + + R EE+++
Sbjct: 7 IEAVKRKIQVLQQQADDAEERAERLQREVEGERRAREQAEAEVASLNRRIQLVEEELDRA 66
Query: 145 EMQLKEAKHIAEDSDRKYEEVARKLVILEGELERSEERAEVAESRARQLEEELRTMDQAL 204
+ +L A E++++ +E SE +V E+RA + EE++ + L
Sbjct: 67 QERLATALQKLEEAEKAADE--------------SERGMKVIENRALKDEEKMELQEIQL 112
Query: 205 KSLMASEEEYSTKEDKYEEEIKLLEEKLKEAETRAEFAERSVAKLEKTIDDLEETLASAK 264
K EE K ++ ++ ++E L+ E RAE AE ++LE+ + ++ L S +
Sbjct: 113 KEAKHIAEEADRKYEEVARKLVIIEGDLERTEERAELAESKCSELEEELKNVTNNLKSLE 172
Query: 265 EENVEIHQTLDQ 276
+ + Q D+
Sbjct: 173 AQAEKYSQKEDK 184
Score = 40.8 bits (94), Expect = 0.001
Identities = 32/140 (22%), Positives = 67/140 (47%), Gaps = 6/140 (4%)
Query: 141 MELQEMQLKEAKHIAEDSDRKYEEVARKLVILEGELE-RSEERAEVAE--SRARQLEEEL 197
+E + +++ + A+D++ + E + R++ EGE R + AEVA R + +EEEL
Sbjct: 7 IEAVKRKIQVLQQQADDAEERAERLQREV---EGERRAREQAEAEVASLNRRIQLVEEEL 63
Query: 198 RTMDQALKSLMASEEEYSTKEDKYEEEIKLLEEKLKEAETRAEFAERSVAKLEKTIDDLE 257
+ L + + EE D+ E +K++E + + E + E E + + + ++ +
Sbjct: 64 DRAQERLATALQKLEEAEKAADESERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEAD 123
Query: 258 ETLASAKEENVEIHQTLDQT 277
+ V I L++T
Sbjct: 124 RKYEEVARKLVIIEGDLERT 143
>gi|114155146 tropomyosin 3 isoform 3 [Homo sapiens]
Length = 247
Score = 315 bits (806), Expect = 4e-86
Identities = 166/238 (69%), Positives = 199/238 (83%)
Query: 44 QALQKKLKGTEDEVEKYSESVKEAQEKLEQAEKKATDAEADVASLNRRIQLVEEELDRAQ 103
+A+++K++ + + + E + Q ++E + AEA+VASLNRRIQLVEEELDRAQ
Sbjct: 8 EAVKRKIQVLQQQADDAEERAERLQREVEGERRAREQAEAEVASLNRRIQLVEEELDRAQ 67
Query: 104 ERLATALQKLEEAEKAADESERGMKVIENRAMKDEEKMELQEMQLKEAKHIAEDSDRKYE 163
ERLATALQKLEEAEKAADESERGMKVIENRA+KDEEKMELQE+QLKEAKHIAE++DRKYE
Sbjct: 68 ERLATALQKLEEAEKAADESERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKYE 127
Query: 164 EVARKLVILEGELERSEERAEVAESRARQLEEELRTMDQALKSLMASEEEYSTKEDKYEE 223
EVARKLVI+EG+LER+EERAE+AESR R+++E++R MDQ LK L A+EE+YS KEDKYEE
Sbjct: 128 EVARKLVIIEGDLERTEERAELAESRCREMDEQIRLMDQNLKCLSAAEEKYSQKEDKYEE 187
Query: 224 EIKLLEEKLKEAETRAEFAERSVAKLEKTIDDLEETLASAKEENVEIHQTLDQTLLEL 281
EIK+L +KLKEAETRAEFAERSVAKLEKTIDDLEE L S E N + L TL +L
Sbjct: 188 EIKILTDKLKEAETRAEFAERSVAKLEKTIDDLEERLYSQLERNRLLSNELKLTLHDL 245
Score = 92.8 bits (229), Expect = 3e-19
Identities = 61/223 (27%), Positives = 119/223 (53%), Gaps = 20/223 (8%)
Query: 1 MDAIKKKMQMLKLDKENAIDRAEQAEADKKQAEDRCKQLEEEQQALQKKLKGTEDEVEKY 60
++A+K+K+Q+L+ ++A +RAE+ + + + +Q E E +L ++++ E+E+++
Sbjct: 7 IEAVKRKIQVLQQQADDAEERAERLQREVEGERRAREQAEAEVASLNRRIQLVEEELDRA 66
Query: 61 SESVKEAQEKLEQAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAA 120
E + A +KLE+AEK A ++E + + R EE+++ + +L A EEA++
Sbjct: 67 QERLATALQKLEEAEKAADESERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKY 126
Query: 121 DESERGMKVIENRAMKDEEKMELQEMQLKE-----------------AKHIAEDSDRKYE 163
+E R + +IE + EE+ EL E + +E A+ + KYE
Sbjct: 127 EEVARKLVIIEGDLERTEERAELAESRCREMDEQIRLMDQNLKCLSAAEEKYSQKEDKYE 186
Query: 164 EVARKLVILEGELERSEERAEVAESRARQLEEELRTMDQALKS 206
E ++ IL +L+ +E RAE AE +LE+ + +++ L S
Sbjct: 187 E---EIKILTDKLKEAETRAEFAERSVAKLEKTIDDLEERLYS 226
Score = 64.3 bits (155), Expect = 1e-10
Identities = 44/184 (23%), Positives = 93/184 (50%), Gaps = 16/184 (8%)
Query: 85 VASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIENRAMKDEEKMELQ 144
+ ++ R+IQ+++++ D A+ER +++E +A +++E + + R EE+++
Sbjct: 7 IEAVKRKIQVLQQQADDAEERAERLQREVEGERRAREQAEAEVASLNRRIQLVEEELDRA 66
Query: 145 EMQLKEAKHIAEDSDRKYEEVARKLVILEGELERSEERAEVAESRARQLEEELRTMDQAL 204
+ +L A E++++ +E SE +V E+RA + EE++ + L
Sbjct: 67 QERLATALQKLEEAEKAADE--------------SERGMKVIENRALKDEEKMELQEIQL 112
Query: 205 KSLMASEEEYSTKEDKYEEEIKLLEEKLKEAETRAEFAERSVAKLEKTIDDLEETL--AS 262
K EE K ++ ++ ++E L+ E RAE AE ++++ I +++ L S
Sbjct: 113 KEAKHIAEEADRKYEEVARKLVIIEGDLERTEERAELAESRCREMDEQIRLMDQNLKCLS 172
Query: 263 AKEE 266
A EE
Sbjct: 173 AAEE 176
Score = 41.6 bits (96), Expect = 8e-04
Identities = 39/181 (21%), Positives = 77/181 (42%), Gaps = 28/181 (15%)
Query: 1 MDAIKKKMQMLKLDKENAIDRAEQAEADKKQAEDRCKQLEEEQQALQKKLKGTEDEVEKY 60
+D ++++ E A A+++E K E+R + EE+ + + +LK + E+
Sbjct: 63 LDRAQERLATALQKLEEAEKAADESERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEA 122
Query: 61 SESVKEAQEKL-------EQAEKKATDAEADVASLNRRIQLV------------------ 95
+E KL E+ E++A AE+ ++ +I+L+
Sbjct: 123 DRKYEEVARKLVIIEGDLERTEERAELAESRCREMDEQIRLMDQNLKCLSAAEEKYSQKE 182
Query: 96 ---EEELDRAQERLATALQKLEEAEKAADESERGMKVIENRAMKDEEKMELQEMQLKEAK 152
EEE+ ++L A + E AE++ + E+ + +E R E+ L +LK
Sbjct: 183 DKYEEEIKILTDKLKEAETRAEFAERSVAKLEKTIDDLEERLYSQLERNRLLSNELKLTL 242
Query: 153 H 153
H
Sbjct: 243 H 243
Score = 40.8 bits (94), Expect = 0.001
Identities = 32/140 (22%), Positives = 67/140 (47%), Gaps = 6/140 (4%)
Query: 141 MELQEMQLKEAKHIAEDSDRKYEEVARKLVILEGELE-RSEERAEVAE--SRARQLEEEL 197
+E + +++ + A+D++ + E + R++ EGE R + AEVA R + +EEEL
Sbjct: 7 IEAVKRKIQVLQQQADDAEERAERLQREV---EGERRAREQAEAEVASLNRRIQLVEEEL 63
Query: 198 RTMDQALKSLMASEEEYSTKEDKYEEEIKLLEEKLKEAETRAEFAERSVAKLEKTIDDLE 257
+ L + + EE D+ E +K++E + + E + E E + + + ++ +
Sbjct: 64 DRAQERLATALQKLEEAEKAADESERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEAD 123
Query: 258 ETLASAKEENVEIHQTLDQT 277
+ V I L++T
Sbjct: 124 RKYEEVARKLVIIEGDLERT 143
>gi|114155148 tropomyosin 3 isoform 5 [Homo sapiens]
Length = 247
Score = 307 bits (786), Expect = 8e-84
Identities = 164/238 (68%), Positives = 195/238 (81%)
Query: 44 QALQKKLKGTEDEVEKYSESVKEAQEKLEQAEKKATDAEADVASLNRRIQLVEEELDRAQ 103
+A+++K++ + + + E + Q ++E + AEA+VASLNRRIQLVEEELDRAQ
Sbjct: 8 EAVKRKIQVLQQQADDAEERAERLQREVEGERRAREQAEAEVASLNRRIQLVEEELDRAQ 67
Query: 104 ERLATALQKLEEAEKAADESERGMKVIENRAMKDEEKMELQEMQLKEAKHIAEDSDRKYE 163
ERLATALQKLEEAEKAADESERGMKVIENRA+KDEEKMELQE+QLKEAKHIAE++DRKYE
Sbjct: 68 ERLATALQKLEEAEKAADESERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKYE 127
Query: 164 EVARKLVILEGELERSEERAEVAESRARQLEEELRTMDQALKSLMASEEEYSTKEDKYEE 223
EVARKLVI+EG+LER+EERAE+AES+ +LEEEL+ + LKSL A E+YS KEDKYEE
Sbjct: 128 EVARKLVIIEGDLERTEERAELAESKCSELEEELKNVTNNLKSLEAQAEKYSQKEDKYEE 187
Query: 224 EIKLLEEKLKEAETRAEFAERSVAKLEKTIDDLEETLASAKEENVEIHQTLDQTLLEL 281
EIK+L +KLKEAETRAEFAERSVAKLEKTIDDLEE L S E N + L TL +L
Sbjct: 188 EIKILTDKLKEAETRAEFAERSVAKLEKTIDDLEERLYSQLERNRLLSNELKLTLHDL 245
Score = 68.2 bits (165), Expect = 8e-12
Identities = 44/192 (22%), Positives = 96/192 (50%), Gaps = 14/192 (7%)
Query: 85 VASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIENRAMKDEEKMELQ 144
+ ++ R+IQ+++++ D A+ER +++E +A +++E + + R EE+++
Sbjct: 7 IEAVKRKIQVLQQQADDAEERAERLQREVEGERRAREQAEAEVASLNRRIQLVEEELDRA 66
Query: 145 EMQLKEAKHIAEDSDRKYEEVARKLVILEGELERSEERAEVAESRARQLEEELRTMDQAL 204
+ +L A E++++ +E SE +V E+RA + EE++ + L
Sbjct: 67 QERLATALQKLEEAEKAADE--------------SERGMKVIENRALKDEEKMELQEIQL 112
Query: 205 KSLMASEEEYSTKEDKYEEEIKLLEEKLKEAETRAEFAERSVAKLEKTIDDLEETLASAK 264
K EE K ++ ++ ++E L+ E RAE AE ++LE+ + ++ L S +
Sbjct: 113 KEAKHIAEEADRKYEEVARKLVIIEGDLERTEERAELAESKCSELEEELKNVTNNLKSLE 172
Query: 265 EENVEIHQTLDQ 276
+ + Q D+
Sbjct: 173 AQAEKYSQKEDK 184
Score = 53.9 bits (128), Expect = 2e-07
Identities = 41/164 (25%), Positives = 89/164 (54%), Gaps = 12/164 (7%)
Query: 124 ERGMKVIENRAMKDEEKMELQEMQLKEAKHIAEDSDRKYEEVARKLVILEGELERSEERA 183
+R ++V++ +A EE+ E + +++ + E ++ + + R++ ++E EL+R++ER
Sbjct: 11 KRKIQVLQQQADDAEERAERLQREVEGERRAREQAEAEVASLNRRIQLVEEELDRAQERL 70
Query: 184 EVAESRARQLEEELRTMDQALKSLMASEEEYSTKEDKYEEEIKLLEEKLKEAETRAEFAE 243
A ++LEE + D++ + + E + K EE+++L E +LKEA+ AE A+
Sbjct: 71 ATA---LQKLEEAEKAADESERGMKVIEN----RALKDEEKMELQEIQLKEAKHIAEEAD 123
Query: 244 RSVAKLEKTIDDLEETLASAKEENVEIHQT----LDQTLLELNN 283
R ++ + + +E L EE E+ ++ L++ L + N
Sbjct: 124 RKYEEVARKLVIIEGDL-ERTEERAELAESKCSELEEELKNVTN 166
Score = 40.8 bits (94), Expect = 0.001
Identities = 32/140 (22%), Positives = 67/140 (47%), Gaps = 6/140 (4%)
Query: 141 MELQEMQLKEAKHIAEDSDRKYEEVARKLVILEGELE-RSEERAEVAE--SRARQLEEEL 197
+E + +++ + A+D++ + E + R++ EGE R + AEVA R + +EEEL
Sbjct: 7 IEAVKRKIQVLQQQADDAEERAERLQREV---EGERRAREQAEAEVASLNRRIQLVEEEL 63
Query: 198 RTMDQALKSLMASEEEYSTKEDKYEEEIKLLEEKLKEAETRAEFAERSVAKLEKTIDDLE 257
+ L + + EE D+ E +K++E + + E + E E + + + ++ +
Sbjct: 64 DRAQERLATALQKLEEAEKAADESERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEAD 123
Query: 258 ETLASAKEENVEIHQTLDQT 277
+ V I L++T
Sbjct: 124 RKYEEVARKLVIIEGDLERT 143
>gi|63252904 tropomyosin 1 alpha chain isoform 6 [Homo sapiens]
Length = 245
Score = 298 bits (762), Expect = 5e-81
Identities = 157/237 (66%), Positives = 190/237 (80%)
Query: 44 QALQKKLKGTEDEVEKYSESVKEAQEKLEQAEKKATDAEADVASLNRRIQLVEEELDRAQ 103
+A+++K++ +++ + E Q +L+ K AEADVASLNRRIQLVEEELDRAQ
Sbjct: 8 EAVRRKIRSLQEQADAAEERAGTLQRELDHERKLRETAEADVASLNRRIQLVEEELDRAQ 67
Query: 104 ERLATALQKLEEAEKAADESERGMKVIENRAMKDEEKMELQEMQLKEAKHIAEDSDRKYE 163
ERLATALQKLEEAEKAADESERGMKVIE+RA KDEEKME+QE+QLKEAKHIAED+DRKYE
Sbjct: 68 ERLATALQKLEEAEKAADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYE 127
Query: 164 EVARKLVILEGELERSEERAEVAESRARQLEEELRTMDQALKSLMASEEEYSTKEDKYEE 223
EVARKLVI+E +LER+EERAE++E + +LEEEL+T+ LKSL A E+YS KED+YEE
Sbjct: 128 EVARKLVIIESDLERAEERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKEDRYEE 187
Query: 224 EIKLLEEKLKEAETRAEFAERSVAKLEKTIDDLEETLASAKEENVEIHQTLDQTLLE 280
EIK+L +KLKEAETRAEFAERSV KLEK+IDDLE+ L E+N + L L E
Sbjct: 188 EIKVLSDKLKEAETRAEFAERSVTKLEKSIDDLEDQLYQQLEQNRRLTNELKLALNE 244
Score = 64.3 bits (155), Expect = 1e-10
Identities = 43/196 (21%), Positives = 99/196 (50%), Gaps = 7/196 (3%)
Query: 3 AIKKKMQMLKLDKENAIDRAEQAEADKKQAEDRCKQLEEEQQALQKKLKGTEDEVEKYSE 62
++ +++Q++ E +DRA++ A Q + ++ +E + + +K E +K E
Sbjct: 51 SLNRRIQLV----EEELDRAQERLATALQKLEEAEKAADESE---RGMKVIESRAQKDEE 103
Query: 63 SVKEAQEKLEQAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADE 122
++ + +L++A+ A DA+ + R++ ++E +L+RA+ER + K E E+
Sbjct: 104 KMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAEERAELSEGKCAELEEELKT 163
Query: 123 SERGMKVIENRAMKDEEKMELQEMQLKEAKHIAEDSDRKYEEVARKLVILEGELERSEER 182
+K +E +A K +K + E ++K ++++ + E R + LE ++ E++
Sbjct: 164 VTNNLKSLEAQAEKYSQKEDRYEEEIKVLSDKLKEAETRAEFAERSVTKLEKSIDDLEDQ 223
Query: 183 AEVAESRARQLEEELR 198
+ R+L EL+
Sbjct: 224 LYQQLEQNRRLTNELK 239
Score = 57.0 bits (136), Expect = 2e-08
Identities = 35/111 (31%), Positives = 60/111 (54%), Gaps = 14/111 (12%)
Query: 2 DAIKKKMQMLKLDKENAIDRAEQAEADKKQAEDRCKQLEEEQQALQKKLKGTEDEVEKYS 61
+ + +K+ +++ D E A +RAE +E +C +LEEE + + LK E + EKYS
Sbjct: 127 EEVARKLVIIESDLERAEERAELSEG-------KCAELEEELKTVTNNLKSLEAQAEKYS 179
Query: 62 -------ESVKEAQEKLEQAEKKATDAEADVASLNRRIQLVEEELDRAQER 105
E +K +KL++AE +A AE V L + I +E++L + E+
Sbjct: 180 QKEDRYEEEIKVLSDKLKEAETRAEFAERSVTKLEKSIDDLEDQLYQQLEQ 230
Score = 49.7 bits (117), Expect = 3e-06
Identities = 42/168 (25%), Positives = 78/168 (46%), Gaps = 22/168 (13%)
Query: 1 MDAIKKKMQMLKLDKENAIDRAEQAEADKKQAEDRCKQLEEEQQALQKKLKGT----EDE 56
+D ++++ E A A+++E K E R ++ EE+ + + +LK ED
Sbjct: 63 LDRAQERLATALQKLEEAEKAADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDA 122
Query: 57 VEKYSESVKEA---QEKLEQAEKKATDAEADVASLNRRIQLVEEEL-------------- 99
KY E ++ + LE+AE++A +E A L ++ V L
Sbjct: 123 DRKYEEVARKLVIIESDLERAEERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKE 182
Query: 100 DRAQERLATALQKLEEAEKAADESERGMKVIENRAMKDEEKMELQEMQ 147
DR +E + KL+EAE A+ +ER + +E +++ D E Q+++
Sbjct: 183 DRYEEEIKVLSDKLKEAETRAEFAERSVTKLE-KSIDDLEDQLYQQLE 229
>gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo
sapiens]
Length = 570
Score = 94.4 bits (233), Expect = 1e-19
Identities = 61/289 (21%), Positives = 145/289 (50%), Gaps = 17/289 (5%)
Query: 2 DAIKKKMQMLKLDKENAIDRAEQAEADKKQAEDRCKQLEEEQQALQKKLKGTEDEVEKYS 61
D + K++Q + + ++ E +Q E++ + EE+ Q ++K++ E+++ +
Sbjct: 256 DHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEREEKIQEQEEKIREQE 315
Query: 62 ESVKEAQEKLEQAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAAD 121
E ++ +E + + E+K E + +I+ +EE++ QE++ +K +E EK +
Sbjct: 316 EKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHE-QEKIREQEEKRQEEEKIRE 374
Query: 122 ESERGMKVIENRAMKDEEKMELQEMQLKEAKHIAEDSDRKYEEVARKLVILEGELERSEE 181
+ +R + E + + EEK+ QE +++E + + ++ + K E K+ E E++ EE
Sbjct: 375 QEKRQEQ--EAKMWRQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMWEQEEEMQEQEE 432
Query: 182 RAEVAESRARQLEEELRTMDQALKS---LMASEEE-----------YSTKEDKYEEEIKL 227
+ E + R+ E+++R ++ ++ +M +EE K + EE+++
Sbjct: 433 KMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMGEQEGKMCEQEAKMQEQEEKMRR 492
Query: 228 LEEKLKEAETRAEFAERSVAKLEKTIDDLEETLASAKEENVEIHQTLDQ 276
EEK++E E + E + + E+ + + EE + +E+ E + + +
Sbjct: 493 QEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQE 541
Score = 91.7 bits (226), Expect = 7e-19
Identities = 59/255 (23%), Positives = 131/255 (51%), Gaps = 6/255 (2%)
Query: 6 KKMQMLKLDKENAIDRAEQAEADKKQAEDRCKQLEEEQQALQKKLKGTEDEVEKYSESVK 65
++ + + +KE + R E+ +K E++ ++LEE+ Q+K++ E++ ++ E ++
Sbjct: 319 RRQEEMMWEKEEKMRRQEEMMWEK---EEKIRELEEKMHE-QEKIREQEEKRQE-EEKIR 373
Query: 66 EAQEKLEQAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESER 125
E QEK ++ E K E + +I+ EE + +E++ +K+ E E+ E E
Sbjct: 374 E-QEKRQEQEAKMWRQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMWEQEEEMQEQEE 432
Query: 126 GMKVIENRAMKDEEKMELQEMQLKEAKHIAEDSDRKYEEVARKLVILEGELERSEERAEV 185
M+ E + + E+K+ QE +++E + + ++ + K E K+ E +++ EE+
Sbjct: 433 KMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMGEQEGKMCEQEAKMQEQEEKMRR 492
Query: 186 AESRARQLEEELRTMDQALKSLMASEEEYSTKEDKYEEEIKLLEEKLKEAETRAEFAERS 245
E + R+ E+++R ++ ++ +E K + EE++ EEK++E E + E
Sbjct: 493 QEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEK 552
Query: 246 VAKLEKTIDDLEETL 260
+ + E + EE +
Sbjct: 553 MREQEVRLRQQEEKM 567
Score = 85.9 bits (211), Expect = 4e-17
Identities = 64/288 (22%), Positives = 139/288 (48%), Gaps = 26/288 (9%)
Query: 1 MDAIKKKMQMLKLDKENAIDRAEQAEADKK-QAEDRCKQLEEEQQALQKKLKGTEDEVEK 59
+ ++ K+Q ++++ +R Q + +K + E++ ++ EE+ Q ++K++ E+++ +
Sbjct: 262 LQSVSAKLQA-QVEENELWNRLNQQQEEKMWRQEEKIQEREEKIQEQEEKIREQEEKMRR 320
Query: 60 YSESVKEAQEKLEQAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKA 119
E + E +EK+ + E+ + E + L ++ E+E R QE +K+ E EK
Sbjct: 321 QEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMH--EQEKIREQEEKRQEEEKIREQEKR 378
Query: 120 ADESERGMKVIENRAMKDEEKMELQEMQLKEAKHIAEDSDRKYEEVARKLVILEGELERS 179
E E M E + + EEK+ QE ++E + + + K E ++ E ++ R
Sbjct: 379 -QEQEAKMWRQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMWEQEEEMQEQEEKMRRQ 437
Query: 180 EERAEVAESRARQLEEELRTMDQALKS------------------LMASEEEYSTKEDKY 221
EE+ E + R+ EE++R ++ ++ + EE+ +E+K
Sbjct: 438 EEKIREQEKKIREQEEKIREQEEMMQEQEEKMGEQEGKMCEQEAKMQEQEEKMRRQEEKI 497
Query: 222 EEEIKLL---EEKLKEAETRAEFAERSVAKLEKTIDDLEETLASAKEE 266
E+ K + EEK++E E + E + + E+ + + EE + +E+
Sbjct: 498 REQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEK 545
Score = 85.9 bits (211), Expect = 4e-17
Identities = 58/276 (21%), Positives = 137/276 (49%), Gaps = 9/276 (3%)
Query: 2 DAIKKKMQMLKLDKENAIDRAEQAEADKK---QAEDRCKQLEEEQQALQKKLKGTEDEVE 58
+ I+++ + ++ +E ++ E+ ++ + E++ ++ EE ++K++ E+++
Sbjct: 295 EKIQEREEKIQEQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMH 354
Query: 59 KYSESVKEAQEKLEQAEK-----KATDAEADVASLNRRIQLVEEELDRAQERLATALQKL 113
+ E ++E +EK ++ EK K + EA + +I+ EE++ +E + +K+
Sbjct: 355 E-QEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEEMMQEQEEKM 413
Query: 114 EEAEKAADESERGMKVIENRAMKDEEKMELQEMQLKEAKHIAEDSDRKYEEVARKLVILE 173
E E+ E E M+ E + + EEK+ QE +++E + + + +E K+ E
Sbjct: 414 GEQEEKMWEQEEEMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMGEQE 473
Query: 174 GELERSEERAEVAESRARQLEEELRTMDQALKSLMASEEEYSTKEDKYEEEIKLLEEKLK 233
G++ E + + E + R+ EE++R ++ ++ E + EE++ EEK+
Sbjct: 474 GKMCEQEAKMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMC 533
Query: 234 EAETRAEFAERSVAKLEKTIDDLEETLASAKEENVE 269
E E + + E + + E+ + + E L +E+ E
Sbjct: 534 EQEEKMQEQEEKMRRQEEKMREQEVRLRQQEEKMQE 569
Score = 83.2 bits (204), Expect = 2e-16
Identities = 57/269 (21%), Positives = 133/269 (49%), Gaps = 11/269 (4%)
Query: 1 MDAIKKKMQMLKLDKENAIDRAEQAEADKKQAEDRCKQLEEEQQALQKKLKGTEDEVEKY 60
+++ K ++Q+ + + ++RA+ ++Q + L +E Q++ KL+ +E E +
Sbjct: 221 VESEKSEIQLNVKELKRKLERAKLL-LPQQQLQAEADHLGKELQSVSAKLQAQVEENELW 279
Query: 61 SESVKEAQEKLEQAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAA 120
+ ++ +EK+ + E+K + E + +I+ EE++ R +E + +K+ E+
Sbjct: 280 NRLNQQQEEKMWRQEEKIQEREEKIQEQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMM 339
Query: 121 DESERGMKVIENRAMKDEEKMELQEMQLKEAKHIAEDSDRKYEEVARKLVILEGELERSE 180
E E ++ +E + M ++EK+ QE + +E + I E R+ + E ++ R E
Sbjct: 340 WEKEEKIRELEEK-MHEQEKIREQEEKRQEEEKIREQEKRQEQ---------EAKMWRQE 389
Query: 181 ERAEVAESRARQLEEELRTMDQALKSLMASEEEYSTKEDKYEEEIKLLEEKLKEAETRAE 240
E+ E + R+ EE ++ ++ + E + + EE+++ EEK++E E +
Sbjct: 390 EKIREQEEKIREQEEMMQEQEEKMGEQEEKMWEQEEEMQEQEEKMRRQEEKIREQEKKIR 449
Query: 241 FAERSVAKLEKTIDDLEETLASAKEENVE 269
E + + E+ + + EE + + + E
Sbjct: 450 EQEEKIREQEEMMQEQEEKMGEQEGKMCE 478
Score = 80.1 bits (196), Expect = 2e-15
Identities = 65/264 (24%), Positives = 132/264 (50%), Gaps = 34/264 (12%)
Query: 37 KQLEEEQQALQKKLKGTEDEVEKYSESVKEAQEKLEQAE----KKATDAEAD-----VAS 87
++L+E+ LQ+KL+ E E + +VKE + KLE+A+ ++ AEAD + S
Sbjct: 205 EELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQS 264
Query: 88 LNRRIQLVEEELD-------RAQERLATALQKLEEAEKAADESERGMKVIENRAMKDEEK 140
++ ++Q EE + + +E++ +K++E E+ E E ++ E + + EE
Sbjct: 265 VSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEREEKIQEQEEKIREQEEKMRRQEEM 324
Query: 141 MELQEMQLKEAKHIAEDSDRKYEEVARKLVILEGELERSEERAE---VAESRARQ----- 192
M +E +++ + + + + K E+ K+ E E+ E+R E + E RQ
Sbjct: 325 MWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAK 384
Query: 193 ---LEEELRTMDQALKS----LMASEEEYSTKEDK---YEEEIKLLEEKLKEAETRAEFA 242
EE++R ++ ++ + EE+ +E+K EEE++ EEK++ E +
Sbjct: 385 MWRQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMWEQEEEMQEQEEKMRRQEEKIREQ 444
Query: 243 ERSVAKLEKTIDDLEETLASAKEE 266
E+ + + E+ I + EE + +E+
Sbjct: 445 EKKIREQEEKIREQEEMMQEQEEK 468
Score = 77.8 bits (190), Expect = 1e-14
Identities = 63/265 (23%), Positives = 130/265 (49%), Gaps = 14/265 (5%)
Query: 19 IDRAEQAEADKKQAEDR-CKQLEEEQQALQKKLKGTEDEVEKYSESVKEAQEKLEQAEKK 77
+++A A A +K+ DR ++L +E+ AL +L E+ E + QEKL+ E +
Sbjct: 165 LEQALSAVATQKKKADRYIEELTKERDALSLELYRNTITDEELKEKNAKLQEKLQLVESE 224
Query: 78 ATDAEADVASLNRRIQ-----LVEEELDRAQERLATALQKLE-EAEKAADESE---RGMK 128
++ + +V L R+++ L +++L + L LQ + + + +E+E R +
Sbjct: 225 KSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEENELWNRLNQ 284
Query: 129 VIENRAMKDEEKMELQEMQLKEAKHIAEDSDRKYEEVARKLVILEGELERSEERAEVAES 188
E + + EEK++ +E +++E + + + K + E ++ R EE E
Sbjct: 285 QQEEKMWRQEEKIQEREEKIQEQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEE 344
Query: 189 RARQLEEELRTMD--QALKSLMASEEEYSTKEDKYEEEIKL--LEEKLKEAETRAEFAER 244
+ R+LEE++ + + + EE+ +E + E+E K+ EEK++E E + E
Sbjct: 345 KIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEE 404
Query: 245 SVAKLEKTIDDLEETLASAKEENVE 269
+ + E+ + + EE + +EE E
Sbjct: 405 MMQEQEEKMGEQEEKMWEQEEEMQE 429
Score = 75.1 bits (183), Expect = 7e-14
Identities = 41/195 (21%), Positives = 101/195 (51%)
Query: 20 DRAEQAEADKKQAEDRCKQLEEEQQALQKKLKGTEDEVEKYSESVKEAQEKLEQAEKKAT 79
++ ++ EA + E++ ++ EE+ + ++ ++ E+++ + E + E +E++++ E+K
Sbjct: 376 EKRQEQEAKMWRQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMWEQEEEMQEQEEKMR 435
Query: 80 DAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIENRAMKDEE 139
E + ++I+ EE++ +E + +K+ E E E E M+ E + + EE
Sbjct: 436 RQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMGEQEGKMCEQEAKMQEQEEKMRRQEE 495
Query: 140 KMELQEMQLKEAKHIAEDSDRKYEEVARKLVILEGELERSEERAEVAESRARQLEEELRT 199
K+ QE +++E + + + +E K+ E ++ EE+ + E + R+ EE++R
Sbjct: 496 KIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMRE 555
Query: 200 MDQALKSLMASEEEY 214
+ L+ +E+
Sbjct: 556 QEVRLRQQEEKMQEH 570
Score = 52.4 bits (124), Expect = 5e-07
Identities = 55/248 (22%), Positives = 111/248 (44%), Gaps = 26/248 (10%)
Query: 33 EDRCKQLEEEQQALQKKLKGTEDEVEKYSESVKEAQEKLEQAEKKATDAEADVASLNRRI 92
ED K + Q+AL+++L+ + + E Q L ++ E + L R+
Sbjct: 96 EDEQKASHQHQEALRRELEAQVQTIRILTCQKTELQMALYYSQHAVKQLEGEARDLISRL 155
Query: 93 Q---LVEEELDRAQERLATALQK----LEEAEKAAD--ESERGMKVIENRAMKD-----E 138
EL++A +AT +K +EE K D E I + +K+ +
Sbjct: 156 HDSWKFAGELEQALSAVATQKKKADRYIEELTKERDALSLELYRNTITDEELKEKNAKLQ 215
Query: 139 EKMELQEMQLKEAKHIAEDSDRKYEEVARKLVILEGELERSEERAEVAESRARQLEEELR 198
EK++L E + E + ++ RK E KL++ + +L ++ A L +EL+
Sbjct: 216 EKLQLVESEKSEIQLNVKELKRKLERA--KLLLPQQQL----------QAEADHLGKELQ 263
Query: 199 TMDQALKSLMASEEEYSTKEDKYEEEIKLLEEKLKEAETRAEFAERSVAKLEKTIDDLEE 258
++ L++ + E ++ + EE++ EEK++E E + + E + + E+ + EE
Sbjct: 264 SVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEREEKIQEQEEKIREQEEKMRRQEE 323
Query: 259 TLASAKEE 266
+ +E+
Sbjct: 324 MMWEKEEK 331
>gi|239745153 PREDICTED: similar to Putative golgin subfamily A
member 6-like protein 6 [Homo sapiens]
Length = 655
Score = 93.6 bits (231), Expect = 2e-19
Identities = 60/254 (23%), Positives = 133/254 (52%), Gaps = 10/254 (3%)
Query: 24 QAEADKKQAEDRCKQLEEEQQALQKKLKGTEDEVEKYSESVKEAQEKLEQAEKKATDAEA 83
+ E ++ E++ + EE+ ++K++ ED++ + E ++E +EK+ + E+K E
Sbjct: 315 EQELKIREQEEKMWRQEEKMHEQEEKIREQEDKMWRQEEKIREQEEKIREQEEKMWRQEE 374
Query: 84 DVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIENRAMKDEEKMEL 143
+ + +IQ EEE+ R +E++ ++ E+ ++ E+ M+ + + + EE+M
Sbjct: 375 KIREQDEKIQEQEEEMWRQEEKIR---EQEEKRQEKMWRQEKKMREQDEKIREQEEEMWR 431
Query: 144 QEMQLKEAKHIAEDSDRKYEEVARKLVILEGELERSEERAEVAESRARQLEEELRTMDQA 203
QE +++E + + +D + K EV K+ E +++ EE+ + E + ++ EE+ ++
Sbjct: 432 QEEKIRELEEMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQRQEEKIQEQEEKTWRQEKL 491
Query: 204 LKSLMASEEEYSTKEDKY---EEEIKLLEEKLKEAETRAEFAERSVAKLEKTIDDLEETL 260
LK EE+ +E+K EE++ EEK++E E + + E + + E + EE +
Sbjct: 492 LKQ----EEKIWEQEEKMWRQEEKMWEQEEKMQEQEEKMQRQEEKMREQEVRLWQQEEKM 547
Query: 261 ASAKEENVEIHQTL 274
+ E+ + L
Sbjct: 548 QEQEVRLQELEERL 561
Score = 87.0 bits (214), Expect = 2e-17
Identities = 66/297 (22%), Positives = 141/297 (47%), Gaps = 38/297 (12%)
Query: 2 DAIKKKMQMLKLDKENAIDRAE-------QAEADKKQAEDRCKQLEEEQQALQKKLKGTE 54
D + K++Q + + ++ E Q E + E++ ++ EE+ + K++ E
Sbjct: 265 DRLGKELQSVSAKLQAQVEENELWNLLNQQQEEKMWRQEEKIQEQEEKMCEQELKIREQE 324
Query: 55 DEVEKYSESVKEAQEKLEQAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLE 114
+++ + E + E +EK+ + E K E + +I+ EE++ R +E++ +K++
Sbjct: 325 EKMWRQEEKMHEQEEKIREQEDKMWRQEEKIREQEEKIREQEEKMWRQEEKIREQDEKIQ 384
Query: 115 E--------AEKAADE----------SERGMKVIENRAMKDEEKMELQEMQLKEAKHIAE 156
E EK ++ E+ M+ + + + EE+M QE +++E + + +
Sbjct: 385 EQEEEMWRQEEKIREQEEKRQEKMWRQEKKMREQDEKIREQEEEMWRQEEKIRELEEMMQ 444
Query: 157 DSDRKYEEVARKLVILEGELERSEERAEVAESRARQLEEELRTMDQALK---SLMASEEE 213
D + K EV K+ E +++ EE+ + E + ++ EE+ ++ LK + EE+
Sbjct: 445 DQEEKLREVEEKMQEEEEKMQEQEEKIQRQEEKIQEQEEKTWRQEKLLKQEEKIWEQEEK 504
Query: 214 YSTKEDK----------YEEEIKLLEEKLKEAETRAEFAERSVAKLEKTIDDLEETL 260
+E+K EE+++ EEK++E E R E + + E + +LEE L
Sbjct: 505 MWRQEEKMWEQEEKMQEQEEKMQRQEEKMREQEVRLWQQEEKMQEQEVRLQELEERL 561
Score = 86.3 bits (212), Expect = 3e-17
Identities = 62/256 (24%), Positives = 130/256 (50%), Gaps = 19/256 (7%)
Query: 37 KQLEEEQQALQKKLKGTEDEVEKYSESVKEAQEKLEQAE----KKATDAEAD-----VAS 87
++L+E+ LQ+KL+ E E + +VK+ + KLE+A+ ++ EAD + S
Sbjct: 214 EELKEKNAELQEKLRLVESEKSEIQLNVKDLKRKLERAQLLLPQQQLQVEADRLGKELQS 273
Query: 88 LNRRIQLVEEELD-------RAQERLATALQKLEEAEKAADESERGMKVIENRAMKDEEK 140
++ ++Q EE + + +E++ +K++E E+ E E ++ E + + EEK
Sbjct: 274 VSAKLQAQVEENELWNLLNQQQEEKMWRQEEKIQEQEEKMCEQELKIREQEEKMWRQEEK 333
Query: 141 MELQEMQLKEAKHIAEDSDRKYEEVARKLVILEGELERSEERAEVAESRARQLEEELRTM 200
M QE +++E + + K E K+ E ++ R EE+ + + ++ EEE+
Sbjct: 334 MHEQEEKIREQEDKMWRQEEKIREQEEKIREQEEKMWRQEEKIREQDEKIQEQEEEMWRQ 393
Query: 201 DQALKSLMASEEEYSTKEDKYEEEIKLLEEKLKEAETRAEFAERSVAKLEKTIDDLEETL 260
++ ++ EE+ K + E++++ +EK++E E E + +LE+ + D EE L
Sbjct: 394 EEKIRE---QEEKRQEKMWRQEKKMREQDEKIREQEEEMWRQEEKIRELEEMMQDQEEKL 450
Query: 261 ASAKEENVEIHQTLDQ 276
+E+ E + + +
Sbjct: 451 REVEEKMQEEEEKMQE 466
Score = 85.1 bits (209), Expect = 6e-17
Identities = 58/258 (22%), Positives = 132/258 (51%), Gaps = 4/258 (1%)
Query: 1 MDAIKKKMQMLKLDKENAIDRAEQAEADKKQAEDRCKQLEEEQQALQKKLKGTEDEVEKY 60
+++ K ++Q+ D + ++RA Q ++Q + +L +E Q++ KL+ +E E +
Sbjct: 230 VESEKSEIQLNVKDLKRKLERA-QLLLPQQQLQVEADRLGKELQSVSAKLQAQVEENELW 288
Query: 61 SESVKEAQEKLEQAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAA 120
+ ++ +EK+ + E+K + E + +I+ EE++ R +E++ +K+ E E
Sbjct: 289 NLLNQQQEEKMWRQEEKIQEQEEKMCEQELKIREQEEKMWRQEEKMHEQEEKIREQEDKM 348
Query: 121 DESERGMKVIENRAMKDEEKMELQEMQLKEAKHIAEDSDRKYEEVARKLVILEGELERSE 180
E ++ E + + EEKM QE +++E ++ + EE+ R+ + + E+ +
Sbjct: 349 WRQEEKIREQEEKIREQEEKMWRQEEKIREQDEKIQEQE---EEMWRQEEKIREQEEKRQ 405
Query: 181 ERAEVAESRARQLEEELRTMDQALKSLMASEEEYSTKEDKYEEEIKLLEEKLKEAETRAE 240
E+ E + R+ +E++R ++ + E EE+++ +EEK++E E + +
Sbjct: 406 EKMWRQEKKMREQDEKIREQEEEMWRQEEKIRELEEMMQDQEEKLREVEEKMQEEEEKMQ 465
Query: 241 FAERSVAKLEKTIDDLEE 258
E + + E+ I + EE
Sbjct: 466 EQEEKIQRQEEKIQEQEE 483
Score = 81.3 bits (199), Expect = 9e-16
Identities = 56/250 (22%), Positives = 127/250 (50%), Gaps = 6/250 (2%)
Query: 20 DRAEQAEADKKQAEDRCKQLEEEQQAL----QKKLKGTEDEVEKYSESVKEAQEKLEQAE 75
++ ++ E + + E++ ++ EE++Q +KK++ ++++ + E + +EK+ + E
Sbjct: 381 EKIQEQEEEMWRQEEKIREQEEKRQEKMWRQEKKMREQDEKIREQEEEMWRQEEKIRELE 440
Query: 76 KKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIENRAM 135
+ D E + + ++Q EE++ +E++ +K++E E+ E+ +K E +
Sbjct: 441 EMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQRQEEKIQEQEEKTWRQEKLLKQ-EEKIW 499
Query: 136 KDEEKMELQEMQLKEAKHIAEDSDRKYEEVARKLVILEGELERSEERAEVAESRARQLEE 195
+ EEKM QE ++ E + ++ + K + K+ E L + EE+ + E R ++LEE
Sbjct: 500 EQEEKMWRQEEKMWEQEEKMQEQEEKMQRQEEKMREQEVRLWQQEEKMQEQEVRLQELEE 559
Query: 196 ELRTMDQALKSLMASEEEYSTKEDKYEEEIKLLEEKLKEAETRAEFAERSVAKLEKTIDD 255
L + Q + L + E ++ I +E K +EA++ + + L++ +
Sbjct: 560 RLGKLGQKAELLGGAGRESGSQRLPTLTPILQVELKSQEAQSLQQQQDHYRGHLQQYVAA 619
Query: 256 LEETLASAKE 265
++ LAS KE
Sbjct: 620 YQQ-LASGKE 628
Score = 76.6 bits (187), Expect = 2e-14
Identities = 50/216 (23%), Positives = 111/216 (51%), Gaps = 2/216 (0%)
Query: 6 KKMQMLKLDKENAIDRAEQAEADKKQAEDRCKQLEEEQQALQKKLKGTEDEVEKYSESVK 65
++ + ++ +E ++ + E ++ +++ ++ EEE ++K++ E+ ++ E ++
Sbjct: 392 RQEEKIREQEEKRQEKMWRQEKKMREQDEKIREQEEEMWRQEEKIRELEEMMQDQEEKLR 451
Query: 66 EAQEKLEQAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESER 125
E +EK+++ E+K + E + +IQ EE+ R QE+L +K+ E E+ E
Sbjct: 452 EVEEKMQEEEEKMQEQEEKIQRQEEKIQEQEEKTWR-QEKLLKQEEKIWEQEEKMWRQEE 510
Query: 126 GMKVIENRAMKDEEKMELQEMQLKEAKHIAEDSDRKYEEVARKLVILEGELERSEERAEV 185
M E + + EEKM+ QE +++E + + K +E +L LE L + ++AE+
Sbjct: 511 KMWEQEEKMQEQEEKMQRQEEKMREQEVRLWQQEEKMQEQEVRLQELEERLGKLGQKAEL 570
Query: 186 AESRARQL-EEELRTMDQALKSLMASEEEYSTKEDK 220
R+ + L T+ L+ + S+E S ++ +
Sbjct: 571 LGGAGRESGSQRLPTLTPILQVELKSQEAQSLQQQQ 606
Score = 75.9 bits (185), Expect = 4e-14
Identities = 48/241 (19%), Positives = 124/241 (51%), Gaps = 19/241 (7%)
Query: 2 DAIKKKMQMLKLDKENAIDRAEQAEADKKQAEDRCKQLEEEQQALQKKLKGTEDEVEKYS 61
D + ++ + ++ +E ++ E+ +++ ++ ++++E+++ + ++ + ++ EK
Sbjct: 346 DKMWRQEEKIREQEEKIREQEEKMWRQEEKIREQDEKIQEQEEEMWRQEEKIREQEEKRQ 405
Query: 62 ESVKEAQEKLEQAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAAD 121
E + ++K+ + ++K + E ++ +I+ +EE + +E+L +K++E E+
Sbjct: 406 EKMWRQEKKMREQDEKIREQEEEMWRQEEKIRELEEMMQDQEEKLREVEEKMQEEEEKMQ 465
Query: 122 ESERGMKVIENRAMKDEEKMELQEMQLKEAKHIAEDSDRKYEEVARKLVILEGELERSEE 181
E E ++ E + + EEK QE LK+ + I E ++ + + E ++ EE
Sbjct: 466 EQEEKIQRQEEKIQEQEEKTWRQEKLLKQEEKIWEQEEKMWRQ--------EEKMWEQEE 517
Query: 182 RAEVAESRARQLEEELRTMDQALKSLMASEEEYSTKEDKYEEEIKL--LEEKLKEAETRA 239
+ + E + ++ EE++R + L + +E E+E++L LEE+L + +A
Sbjct: 518 KMQEQEEKMQRQEEKMREQEVRL---------WQQEEKMQEQEVRLQELEERLGKLGQKA 568
Query: 240 E 240
E
Sbjct: 569 E 569
Score = 70.1 bits (170), Expect = 2e-12
Identities = 63/304 (20%), Positives = 137/304 (45%), Gaps = 34/304 (11%)
Query: 7 KMQMLKLDKENAIDRAEQAEADKKQAEDRCKQLEEEQQALQKKLKGTEDEVEKYSESVKE 66
K L+L + A R E + ++ D ++ + L K+ E+ + + + +E
Sbjct: 156 KKPWLRLGEVTAQKRPENSLLEETLHFDHAVRMGTYIEKLTKERDAPSLELYRNTITDEE 215
Query: 67 AQEKLEQAEKKATDAEADVASLNRRIQLVEEELDRAQ------------ERLATALQKLE 114
+EK + ++K E++ + + ++ ++ +L+RAQ +RL LQ +
Sbjct: 216 LKEKNAELQEKLRLVESEKSEIQLNVKDLKRKLERAQLLLPQQQLQVEADRLGKELQSVS 275
Query: 115 EAEKAA-----------DESERGMKVIENRAMKDEEKMELQEMQLKEAKHIAEDSDRKYE 163
+A + E M E + + EEKM QE++++E + + K
Sbjct: 276 AKLQAQVEENELWNLLNQQQEEKMWRQEEKIQEQEEKMCEQELKIREQEEKMWRQEEKMH 335
Query: 164 EVARKLVILEGELERSEERAEVAESRARQ-------LEEELRTMDQAL----KSLMASEE 212
E K+ E ++ R EE+ E + R+ EE++R D+ + + + EE
Sbjct: 336 EQEEKIREQEDKMWRQEEKIREQEEKIREQEEKMWRQEEKIREQDEKIQEQEEEMWRQEE 395
Query: 213 EYSTKEDKYEEEIKLLEEKLKEAETRAEFAERSVAKLEKTIDDLEETLASAKEENVEIHQ 272
+ +E+K +E++ E+K++E + + E + + E+ I +LEE + +E+ E+ +
Sbjct: 396 KIREQEEKRQEKMWRQEKKMREQDEKIREQEEEMWRQEEKIRELEEMMQDQEEKLREVEE 455
Query: 273 TLDQ 276
+ +
Sbjct: 456 KMQE 459
>gi|239745127 PREDICTED: similar to Putative golgin subfamily A
member 6-like protein 6 [Homo sapiens]
Length = 655
Score = 93.6 bits (231), Expect = 2e-19
Identities = 60/254 (23%), Positives = 133/254 (52%), Gaps = 10/254 (3%)
Query: 24 QAEADKKQAEDRCKQLEEEQQALQKKLKGTEDEVEKYSESVKEAQEKLEQAEKKATDAEA 83
+ E ++ E++ + EE+ ++K++ ED++ + E ++E +EK+ + E+K E
Sbjct: 315 EQELKIREQEEKMWRQEEKMHEQEEKIREQEDKMWRQEEKIREQEEKIREQEEKMWRQEE 374
Query: 84 DVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIENRAMKDEEKMEL 143
+ + +IQ EEE+ R +E++ ++ E+ ++ E+ M+ + + + EE+M
Sbjct: 375 KIREQDEKIQEQEEEMWRQEEKIR---EQEEKRQEKMWRQEKKMREQDEKIREQEEEMWR 431
Query: 144 QEMQLKEAKHIAEDSDRKYEEVARKLVILEGELERSEERAEVAESRARQLEEELRTMDQA 203
QE +++E + + +D + K EV K+ E +++ EE+ + E + ++ EE+ ++
Sbjct: 432 QEEKIRELEEMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQRQEEKIQEQEEKTWRQEKL 491
Query: 204 LKSLMASEEEYSTKEDKY---EEEIKLLEEKLKEAETRAEFAERSVAKLEKTIDDLEETL 260
LK EE+ +E+K EE++ EEK++E E + + E + + E + EE +
Sbjct: 492 LKQ----EEKIWEQEEKMWRQEEKMWEQEEKMQEQEEKMQRQEEKMREQEVRLWQQEEKM 547
Query: 261 ASAKEENVEIHQTL 274
+ E+ + L
Sbjct: 548 QEQEVRLQELEERL 561
Score = 87.0 bits (214), Expect = 2e-17
Identities = 66/297 (22%), Positives = 141/297 (47%), Gaps = 38/297 (12%)
Query: 2 DAIKKKMQMLKLDKENAIDRAE-------QAEADKKQAEDRCKQLEEEQQALQKKLKGTE 54
D + K++Q + + ++ E Q E + E++ ++ EE+ + K++ E
Sbjct: 265 DRLGKELQSVSAKLQAQVEENELWNLLNQQQEEKMWRQEEKIQEQEEKMCEQELKIREQE 324
Query: 55 DEVEKYSESVKEAQEKLEQAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLE 114
+++ + E + E +EK+ + E K E + +I+ EE++ R +E++ +K++
Sbjct: 325 EKMWRQEEKMHEQEEKIREQEDKMWRQEEKIREQEEKIREQEEKMWRQEEKIREQDEKIQ 384
Query: 115 E--------AEKAADE----------SERGMKVIENRAMKDEEKMELQEMQLKEAKHIAE 156
E EK ++ E+ M+ + + + EE+M QE +++E + + +
Sbjct: 385 EQEEEMWRQEEKIREQEEKRQEKMWRQEKKMREQDEKIREQEEEMWRQEEKIRELEEMMQ 444
Query: 157 DSDRKYEEVARKLVILEGELERSEERAEVAESRARQLEEELRTMDQALK---SLMASEEE 213
D + K EV K+ E +++ EE+ + E + ++ EE+ ++ LK + EE+
Sbjct: 445 DQEEKLREVEEKMQEEEEKMQEQEEKIQRQEEKIQEQEEKTWRQEKLLKQEEKIWEQEEK 504
Query: 214 YSTKEDK----------YEEEIKLLEEKLKEAETRAEFAERSVAKLEKTIDDLEETL 260
+E+K EE+++ EEK++E E R E + + E + +LEE L
Sbjct: 505 MWRQEEKMWEQEEKMQEQEEKMQRQEEKMREQEVRLWQQEEKMQEQEVRLQELEERL 561
Score = 86.3 bits (212), Expect = 3e-17
Identities = 62/256 (24%), Positives = 130/256 (50%), Gaps = 19/256 (7%)
Query: 37 KQLEEEQQALQKKLKGTEDEVEKYSESVKEAQEKLEQAE----KKATDAEAD-----VAS 87
++L+E+ LQ+KL+ E E + +VK+ + KLE+A+ ++ EAD + S
Sbjct: 214 EELKEKNAELQEKLRLVESEKSEIQLNVKDLKRKLERAQLLLPQQQLQVEADRLGKELQS 273
Query: 88 LNRRIQLVEEELD-------RAQERLATALQKLEEAEKAADESERGMKVIENRAMKDEEK 140
++ ++Q EE + + +E++ +K++E E+ E E ++ E + + EEK
Sbjct: 274 VSAKLQAQVEENELWNLLNQQQEEKMWRQEEKIQEQEEKMCEQELKIREQEEKMWRQEEK 333
Query: 141 MELQEMQLKEAKHIAEDSDRKYEEVARKLVILEGELERSEERAEVAESRARQLEEELRTM 200
M QE +++E + + K E K+ E ++ R EE+ + + ++ EEE+
Sbjct: 334 MHEQEEKIREQEDKMWRQEEKIREQEEKIREQEEKMWRQEEKIREQDEKIQEQEEEMWRQ 393
Query: 201 DQALKSLMASEEEYSTKEDKYEEEIKLLEEKLKEAETRAEFAERSVAKLEKTIDDLEETL 260
++ ++ EE+ K + E++++ +EK++E E E + +LE+ + D EE L
Sbjct: 394 EEKIRE---QEEKRQEKMWRQEKKMREQDEKIREQEEEMWRQEEKIRELEEMMQDQEEKL 450
Query: 261 ASAKEENVEIHQTLDQ 276
+E+ E + + +
Sbjct: 451 REVEEKMQEEEEKMQE 466
Score = 85.1 bits (209), Expect = 6e-17
Identities = 58/258 (22%), Positives = 132/258 (51%), Gaps = 4/258 (1%)
Query: 1 MDAIKKKMQMLKLDKENAIDRAEQAEADKKQAEDRCKQLEEEQQALQKKLKGTEDEVEKY 60
+++ K ++Q+ D + ++RA Q ++Q + +L +E Q++ KL+ +E E +
Sbjct: 230 VESEKSEIQLNVKDLKRKLERA-QLLLPQQQLQVEADRLGKELQSVSAKLQAQVEENELW 288
Query: 61 SESVKEAQEKLEQAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAA 120
+ ++ +EK+ + E+K + E + +I+ EE++ R +E++ +K+ E E
Sbjct: 289 NLLNQQQEEKMWRQEEKIQEQEEKMCEQELKIREQEEKMWRQEEKMHEQEEKIREQEDKM 348
Query: 121 DESERGMKVIENRAMKDEEKMELQEMQLKEAKHIAEDSDRKYEEVARKLVILEGELERSE 180
E ++ E + + EEKM QE +++E ++ + EE+ R+ + + E+ +
Sbjct: 349 WRQEEKIREQEEKIREQEEKMWRQEEKIREQDEKIQEQE---EEMWRQEEKIREQEEKRQ 405
Query: 181 ERAEVAESRARQLEEELRTMDQALKSLMASEEEYSTKEDKYEEEIKLLEEKLKEAETRAE 240
E+ E + R+ +E++R ++ + E EE+++ +EEK++E E + +
Sbjct: 406 EKMWRQEKKMREQDEKIREQEEEMWRQEEKIRELEEMMQDQEEKLREVEEKMQEEEEKMQ 465
Query: 241 FAERSVAKLEKTIDDLEE 258
E + + E+ I + EE
Sbjct: 466 EQEEKIQRQEEKIQEQEE 483
Score = 81.3 bits (199), Expect = 9e-16
Identities = 56/250 (22%), Positives = 127/250 (50%), Gaps = 6/250 (2%)
Query: 20 DRAEQAEADKKQAEDRCKQLEEEQQAL----QKKLKGTEDEVEKYSESVKEAQEKLEQAE 75
++ ++ E + + E++ ++ EE++Q +KK++ ++++ + E + +EK+ + E
Sbjct: 381 EKIQEQEEEMWRQEEKIREQEEKRQEKMWRQEKKMREQDEKIREQEEEMWRQEEKIRELE 440
Query: 76 KKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIENRAM 135
+ D E + + ++Q EE++ +E++ +K++E E+ E+ +K E +
Sbjct: 441 EMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQRQEEKIQEQEEKTWRQEKLLKQ-EEKIW 499
Query: 136 KDEEKMELQEMQLKEAKHIAEDSDRKYEEVARKLVILEGELERSEERAEVAESRARQLEE 195
+ EEKM QE ++ E + ++ + K + K+ E L + EE+ + E R ++LEE
Sbjct: 500 EQEEKMWRQEEKMWEQEEKMQEQEEKMQRQEEKMREQEVRLWQQEEKMQEQEVRLQELEE 559
Query: 196 ELRTMDQALKSLMASEEEYSTKEDKYEEEIKLLEEKLKEAETRAEFAERSVAKLEKTIDD 255
L + Q + L + E ++ I +E K +EA++ + + L++ +
Sbjct: 560 RLGKLGQKAELLGGAGRESGSQRLPTLTPILQVELKSQEAQSLQQQQDHYRGHLQQYVAA 619
Query: 256 LEETLASAKE 265
++ LAS KE
Sbjct: 620 YQQ-LASGKE 628
Score = 76.6 bits (187), Expect = 2e-14
Identities = 50/216 (23%), Positives = 111/216 (51%), Gaps = 2/216 (0%)
Query: 6 KKMQMLKLDKENAIDRAEQAEADKKQAEDRCKQLEEEQQALQKKLKGTEDEVEKYSESVK 65
++ + ++ +E ++ + E ++ +++ ++ EEE ++K++ E+ ++ E ++
Sbjct: 392 RQEEKIREQEEKRQEKMWRQEKKMREQDEKIREQEEEMWRQEEKIRELEEMMQDQEEKLR 451
Query: 66 EAQEKLEQAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESER 125
E +EK+++ E+K + E + +IQ EE+ R QE+L +K+ E E+ E
Sbjct: 452 EVEEKMQEEEEKMQEQEEKIQRQEEKIQEQEEKTWR-QEKLLKQEEKIWEQEEKMWRQEE 510
Query: 126 GMKVIENRAMKDEEKMELQEMQLKEAKHIAEDSDRKYEEVARKLVILEGELERSEERAEV 185
M E + + EEKM+ QE +++E + + K +E +L LE L + ++AE+
Sbjct: 511 KMWEQEEKMQEQEEKMQRQEEKMREQEVRLWQQEEKMQEQEVRLQELEERLGKLGQKAEL 570
Query: 186 AESRARQL-EEELRTMDQALKSLMASEEEYSTKEDK 220
R+ + L T+ L+ + S+E S ++ +
Sbjct: 571 LGGAGRESGSQRLPTLTPILQVELKSQEAQSLQQQQ 606
Score = 75.9 bits (185), Expect = 4e-14
Identities = 48/241 (19%), Positives = 124/241 (51%), Gaps = 19/241 (7%)
Query: 2 DAIKKKMQMLKLDKENAIDRAEQAEADKKQAEDRCKQLEEEQQALQKKLKGTEDEVEKYS 61
D + ++ + ++ +E ++ E+ +++ ++ ++++E+++ + ++ + ++ EK
Sbjct: 346 DKMWRQEEKIREQEEKIREQEEKMWRQEEKIREQDEKIQEQEEEMWRQEEKIREQEEKRQ 405
Query: 62 ESVKEAQEKLEQAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAAD 121
E + ++K+ + ++K + E ++ +I+ +EE + +E+L +K++E E+
Sbjct: 406 EKMWRQEKKMREQDEKIREQEEEMWRQEEKIRELEEMMQDQEEKLREVEEKMQEEEEKMQ 465
Query: 122 ESERGMKVIENRAMKDEEKMELQEMQLKEAKHIAEDSDRKYEEVARKLVILEGELERSEE 181
E E ++ E + + EEK QE LK+ + I E ++ + + E ++ EE
Sbjct: 466 EQEEKIQRQEEKIQEQEEKTWRQEKLLKQEEKIWEQEEKMWRQ--------EEKMWEQEE 517
Query: 182 RAEVAESRARQLEEELRTMDQALKSLMASEEEYSTKEDKYEEEIKL--LEEKLKEAETRA 239
+ + E + ++ EE++R + L + +E E+E++L LEE+L + +A
Sbjct: 518 KMQEQEEKMQRQEEKMREQEVRL---------WQQEEKMQEQEVRLQELEERLGKLGQKA 568
Query: 240 E 240
E
Sbjct: 569 E 569
Score = 72.4 bits (176), Expect = 4e-13
Identities = 64/274 (23%), Positives = 123/274 (44%), Gaps = 41/274 (14%)
Query: 37 KQLEEEQQALQKKLKGTEDEVEKYSESVKEAQEKLEQAEKKATDAEADVASLNRRIQLVE 96
++L +E+ AL +L E+ E E QEKL E + ++ + +V L R+
Sbjct: 193 EKLTKERDALSLELYRNTITDEELKEKNAELQEKLRLVESEKSEIQLNVKDLKRK----- 247
Query: 97 EELDRAQ------------ERLATALQKLEEAEKAA-----------DESERGMKVIENR 133
L+RAQ +RL LQ + +A + E M E +
Sbjct: 248 --LERAQLLLPQQQLQVEADRLGKELQSVSAKLQAQVEENELWNLLNQQQEEKMWRQEEK 305
Query: 134 AMKDEEKMELQEMQLKEAKHIAEDSDRKYEEVARKLVILEGELERSEERAEVAESRARQ- 192
+ EEKM QE++++E + + K E K+ E ++ R EE+ E + R+
Sbjct: 306 IQEQEEKMCEQELKIREQEEKMWRQEEKMHEQEEKIREQEDKMWRQEEKIREQEEKIREQ 365
Query: 193 ------LEEELRTMDQAL----KSLMASEEEYSTKEDKYEEEIKLLEEKLKEAETRAEFA 242
EE++R D+ + + + EE+ +E+K +E++ E+K++E + +
Sbjct: 366 EEKMWRQEEKIREQDEKIQEQEEEMWRQEEKIREQEEKRQEKMWRQEKKMREQDEKIREQ 425
Query: 243 ERSVAKLEKTIDDLEETLASAKEENVEIHQTLDQ 276
E + + E+ I +LEE + +E+ E+ + + +
Sbjct: 426 EEEMWRQEEKIRELEEMMQDQEEKLREVEEKMQE 459
>gi|62243484 sarcoma antigen NY-SAR-41 [Homo sapiens]
Length = 1417
Score = 86.7 bits (213), Expect = 2e-17
Identities = 81/291 (27%), Positives = 140/291 (48%), Gaps = 24/291 (8%)
Query: 11 LKLDKENAIDRAEQAEADKKQAEDRCKQLEEEQQALQKKLKGTEDEVEKYSE-------S 63
L++ KE + Q E +K++ E + K+ EE LQK+LK +++ SE +
Sbjct: 851 LEICKEELVLHLNQLEGNKEKFEKQLKKKSEEVYCLQKELKIKNHSLQETSEQNVILQHT 910
Query: 64 VKEAQEKLEQAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEE-AEKAADE 122
+++ Q+ L+Q + + E L +++ +E+EL + +E A L+K+EE E AA E
Sbjct: 911 LQQQQQMLQQETIRNGELEDTQTKLEKQVSKLEQELQKQRESSAEKLRKMEEKCESAAHE 970
Query: 123 SE-RGMKVIE----NRAMK---DEEKMELQEMQLKEAKHIAEDSDRKYEEVARKLVILEG 174
++ + KVIE R +K D+ K EL +M+ KE H+ D + K A L L+
Sbjct: 971 ADLKRQKVIELTGTARQVKIEMDQYKEELSKME-KEIMHLKRDGENK----AMHLSQLDM 1025
Query: 175 ELERSEERAEVAESRARQLEEELRTMDQALKSLMASEEEYSTKEDKYEEEIKLLEEKLKE 234
L++++ E + ++LE+ + + L + E T+ E+K +L+E
Sbjct: 1026 ILDQTKTELEKKTNAVKELEKLQHSTETELTEALQKREVLETELQNAHGELKSTLRQLQE 1085
Query: 235 AETRAEFAERSVAKLEKTIDDLEETLASAKEENVEIHQTL---DQTLLELN 282
+ A+ S+ + TI DL L K E + Q L DQ L E N
Sbjct: 1086 LRDVLQKAQLSLEEKYTTIKDLTAELRECKMEIEDKKQELLEMDQALKERN 1136
Score = 68.2 bits (165), Expect = 8e-12
Identities = 63/276 (22%), Positives = 130/276 (47%), Gaps = 26/276 (9%)
Query: 23 EQAEADKKQAEDRCKQLEEEQQALQKKLKGTEDEVEKYSES----VKEAQEKLEQAEKKA 78
+Q + +Q R +LE+ Q L+K++ E E++K ES +++ +EK E A +A
Sbjct: 912 QQQQQMLQQETIRNGELEDTQTKLEKQVSKLEQELQKQRESSAEKLRKMEEKCESAAHEA 971
Query: 79 TDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIENRAMKDE 138
V L + V+ E+D+ +E L+ +++ ++ D + M + + + D+
Sbjct: 972 DLKRQKVIELTGTARQVKIEMDQYKEELSKMEKEIMHLKR--DGENKAMHLSQLDMILDQ 1029
Query: 139 EKMELQEM--QLKEAKHIAEDSDRKYEEVARKLVILEGELERS-----------EERAEV 185
K EL++ +KE + + ++ + E +K +LE EL+ + +E +V
Sbjct: 1030 TKTELEKKTNAVKELEKLQHSTETELTEALQKREVLETELQNAHGELKSTLRQLQELRDV 1089
Query: 186 AESRARQLEEELRTMDQALKSLMASEEEYSTKEDKYEEEIKLLEEKLKEAETRAEFAERS 245
+ LEE+ T +K L A E + + ++E+ +++ LKE +
Sbjct: 1090 LQKAQLSLEEKYTT----IKDLTAELRECKMEIEDKKQELLEMDQALKERNWELKQRAAQ 1145
Query: 246 VAKLEKTIDDLEETLASAKEENVEIHQTLDQTLLEL 281
V L+ TI E +++ +++ TL+++ LEL
Sbjct: 1146 VTHLDMTI---REHRGEMEQKIIKLEGTLEKSELEL 1178
Score = 67.4 bits (163), Expect = 1e-11
Identities = 64/283 (22%), Positives = 130/283 (45%), Gaps = 21/283 (7%)
Query: 1 MDAIKKKMQMLKLDKENAIDRAEQAEADKKQAEDRCKQLEEEQQALQKKLKGTEDEVEKY 60
+ ++K++ LK D EN Q + Q + ++ + L+K TE E+
Sbjct: 999 LSKMEKEIMHLKRDGENKAMHLSQLDMILDQTKTELEKKTNAVKELEKLQHSTETELT-- 1056
Query: 61 SESVKEAQEKLEQAEKKATDAEADVASLNRRIQLVEEELDRAQ---ERLATALQKL--EE 115
EA +K E E + +A ++ S R++Q + + L +AQ E T ++ L E
Sbjct: 1057 -----EALQKREVLETELQNAHGELKSTLRQLQELRDVLQKAQLSLEEKYTTIKDLTAEL 1111
Query: 116 AEKAADESERGMKVIENRAMKDEEKMELQEMQLKEAKHIAEDSDRKYEEVARKLVILEGE 175
E + ++ +++E E EL++ + + H+ E+ +K++ LEG
Sbjct: 1112 RECKMEIEDKKQELLEMDQALKERNWELKQ-RAAQVTHLDMTIREHRGEMEQKIIKLEGT 1170
Query: 176 LERSEERAEVAESRARQLEEELRTMDQALKS----LMASEEEYSTKEDKYEEEIKLLEEK 231
LE+SE + + L ++L+ + L+ ++ +E+E S + ++EI+ +++
Sbjct: 1171 LEKSELELKECNKQIESLNDKLQNAKEQLREKEFIMLQNEQEIS----QLKKEIERTQQR 1226
Query: 232 LKEAETRAEFAERSVAKLEKTIDDLEETLASAKEENVEIHQTL 274
+KE E+ + E+ +A K DL + L +E+ H L
Sbjct: 1227 MKEMESVMKEQEQYIATQYKEAIDLGQELRLTREQVQNSHTEL 1269
Score = 63.2 bits (152), Expect = 3e-10
Identities = 67/322 (20%), Positives = 140/322 (43%), Gaps = 59/322 (18%)
Query: 2 DAIKKKMQMLKLDKENAIDRAEQAEADKKQAEDRCKQLEEEQQALQKK---LKGTEDEVE 58
D ++K L+ D + K + ED+ ++L E QAL+++ LK +V
Sbjct: 1088 DVLQKAQLSLEEKYTTIKDLTAELRECKMEIEDKKQELLEMDQALKERNWELKQRAAQVT 1147
Query: 59 KYSESVKEAQEKLEQ-----------AEKKATDAEADVASLNRRIQLVEEELDRAQERLA 107
+++E + ++EQ +E + + + SLN ++Q +E+L + +
Sbjct: 1148 HLDMTIREHRGEMEQKIIKLEGTLEKSELELKECNKQIESLNDKLQNAKEQLREKEFIML 1207
Query: 108 TALQKLEEAEKAADESERGMKVIENRAMKDE----------------------EKMELQE 145
Q++ + +K + +++ MK +E+ MK++ E+++
Sbjct: 1208 QNEQEISQLKKEIERTQQRMKEMES-VMKEQEQYIATQYKEAIDLGQELRLTREQVQNSH 1266
Query: 146 MQLKEAKHIAEDSDRKYEEVARKLV--------------ILEGELERSEERAEVAESR-- 189
+L EA+H + R+ E ++ +L L EL S+ R E+R
Sbjct: 1267 TELAEARHQQVQAQREIERLSSELEDMKQLSKEKDAHGNHLAEELGASKVREAHLEARMQ 1326
Query: 190 --ARQLEEELRTMDQALKSLMASEEEYSTK----EDKYEEEIKLLEEKLKEAETRAEFAE 243
++L E+ ++ +A M S +E K D + ++ L E+L++A+ E A+
Sbjct: 1327 AEIKKLSAEVESLKEAYHMEMISHQENHAKWKISADSQKSSVQQLNEQLEKAKLELEEAQ 1386
Query: 244 RSVAKLEKTIDDLEETLASAKE 265
+V+ L + + D E + +A E
Sbjct: 1387 DTVSNLHQQVQDRNEVIEAANE 1408
Score = 61.2 bits (147), Expect = 1e-09
Identities = 65/292 (22%), Positives = 134/292 (45%), Gaps = 21/292 (7%)
Query: 5 KKKMQMLKLDKENAIDRAEQAEADKKQAEDRCKQLEEEQQALQKK---LKGT----EDEV 57
K + Q+ KL++E R AE +K E++C+ E ++K L GT + E+
Sbjct: 934 KLEKQVSKLEQELQKQRESSAEKLRKM-EEKCESAAHEADLKRQKVIELTGTARQVKIEM 992
Query: 58 EKYSESVKEAQEKLEQAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEA- 116
++Y E + + ++++ ++ + ++ L+ + + EL++ + L+KL+ +
Sbjct: 993 DQYKEELSKMEKEIMHLKRDGENKAMHLSQLDMILDQTKTELEK-KTNAVKELEKLQHST 1051
Query: 117 EKAADESERGMKVIENRAMKDEEKMELQEMQLKEAKHIAEDSDRKYEEVARKLVILEGEL 176
E E+ + +V+E +++ QL+E + + + + EE + L EL
Sbjct: 1052 ETELTEALQKREVLETELQNAHGELKSTLRQLQELRDVLQKAQLSLEEKYTTIKDLTAEL 1111
Query: 177 ERSEERAEVAESRARQLEEELRTMDQALK----SLMASEEEYSTKEDKYEEEIKLLEEKL 232
E + E+ + + +EL MDQALK L + + + E +E+K+
Sbjct: 1112 R--ECKMEIEDKK-----QELLEMDQALKERNWELKQRAAQVTHLDMTIREHRGEMEQKI 1164
Query: 233 KEAETRAEFAERSVAKLEKTIDDLEETLASAKEENVEIHQTLDQTLLELNNL 284
+ E E +E + + K I+ L + L +AKE+ E + Q E++ L
Sbjct: 1165 IKLEGTLEKSELELKECNKQIESLNDKLQNAKEQLREKEFIMLQNEQEISQL 1216
Score = 58.5 bits (140), Expect = 6e-09
Identities = 59/285 (20%), Positives = 121/285 (42%), Gaps = 38/285 (13%)
Query: 1 MDAIKKKMQMLKLDKENAIDRAEQAEADKKQAEDRCKQLEEEQQA------LQKKLKGTE 54
++ ++++ L + + + E + Q+ + LE QQ L++++ E
Sbjct: 238 LNKLRQQNACLVTQNHSLMTKFESIHFELTQSRAKVSMLESAQQQAASVPILEEQIINLE 297
Query: 55 DEVEKYSESVKEAQEKLEQAEKKATDAEADVAS-----LNRRIQLVE------------- 96
EV + ++EA+ KLEQ++K + E + + ++ L+E
Sbjct: 298 AEVSAQDKVLREAENKLEQSQKMVIEKEQSLQESKEECIKLKVDLLEQTKQGKRAERQRN 357
Query: 97 ------EELDRA-QERLATALQKLEEAEKAADESERGMKVIENRAMKDEEKMELQEMQLK 149
EEL +A Q+ +KLE+ + + ER + E + +E+ L + +L+
Sbjct: 358 EALYNAEELSKAFQQYKKKVAEKLEKVQAEEEILERNLTNCEKENKRLQERCGLYKSELE 417
Query: 150 EAKHIAEDSDRKYEEVARKLVILEGELERSEERAEVAESRAR--QLEEELRTMDQALK-- 205
K + KL I+ ++ SE A++ ESR +LE EL D+ L+
Sbjct: 418 ILKEKLRQLKEENNNGKEKLRIM--AVKNSEVMAQLTESRQSILKLESELENKDEILRDK 475
Query: 206 -SLMASEEEYSTKEDKYEEEIKLLEEKLKEAETRAEFAERSVAKL 249
SLM E + E + L +++++ + E+ +++L
Sbjct: 476 FSLMNENRELKVRVAAQNERLDLCQQEIESSRVELRSLEKIISQL 520
Score = 55.8 bits (133), Expect = 4e-08
Identities = 53/245 (21%), Positives = 108/245 (44%), Gaps = 32/245 (13%)
Query: 40 EEEQQALQKKLKGTEDEVEKYSESVKEAQEKLEQAEKKATDAEADVASLNRRIQLVEEEL 99
++ Q + K+ E E ++ ++E + KL Q E + +D + ++A + QL++EEL
Sbjct: 622 DQNQHTMNKQY---EKERQRLVTGIEELRTKLIQIEAENSDLKVNMAHRTSQFQLIQEEL 678
Query: 100 DRAQERLATALQKLEEAEKAADESERGMKVIENRAMKDEEKMELQEMQLKEAKHIAEDSD 159
EKA++ S+ +E+ K ++ E QL+E K +A
Sbjct: 679 ----------------LEKASNSSK-----LESEMTKKCSQLLTLEKQLEE-KIVA---- 712
Query: 160 RKYEEVARKLVILEGELERSEERAEVAESRARQLEEEL-RTMDQALKSLMASEEEYSTKE 218
Y +A K LE EL E+ E+ E++ ++A K + +E +
Sbjct: 713 --YSSIAAKNAELEQELMEKNEKIRSLETNINTEHEKICLAFEKAKKIHLEQHKEMEKQI 770
Query: 219 DKYEEEIKLLEEKLKEAETRAEFAERSVAKLEKTIDDLEETLASAKEENVEIHQTLDQTL 278
++ E +++ +++ KE E ++ + + ++ L+ L +K E + + D+ L
Sbjct: 771 ERLEAQLEKKDQQFKEQEKTMSMLQQDIICKQHHLESLDRLLTESKGEMKKENMKKDEAL 830
Query: 279 LELNN 283
L N
Sbjct: 831 KALQN 835
Score = 55.1 bits (131), Expect = 7e-08
Identities = 57/276 (20%), Positives = 118/276 (42%), Gaps = 21/276 (7%)
Query: 12 KLDKENAIDRAEQAEADKKQAEDRCKQLEEEQQALQKKLKGTEDEVEKYSESVKEAQEKL 71
K ++ + + + K ++ +L ++ L + + E + +++ K+
Sbjct: 214 KKPRDKMFSSSAPVDQEIKSLREKLNKLRQQNACLVTQNHSLMTKFESIHFELTQSRAKV 273
Query: 72 EQAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIE 131
E A A V L +I +E E+ + L A KLE+++K E E+ ++ +
Sbjct: 274 SMLESAQQQA-ASVPILEEQIINLEAEVSAQDKVLREAENKLEQSQKMVIEKEQSLQESK 332
Query: 132 NRAMK-------DEEKMELQEMQLKEAKHIAEDSDRKYEEVARKLVILEGELERSEERAE 184
+K ++ + E Q EA + AE+ + +++ +K+ +LE+ + E
Sbjct: 333 EECIKLKVDLLEQTKQGKRAERQRNEALYNAEELSKAFQQYKKKVA---EKLEKVQAEEE 389
Query: 185 VAESRARQLEEELRTMDQALKSLMASEEEYSTKEDKYEEEIKLLEEKL-----KEAETRA 239
+ E E+E + + + + E K + +EE +EKL K +E A
Sbjct: 390 ILERNLTNCEKENKRLQERCGLYKSELEILKEKLRQLKEENNNGKEKLRIMAVKNSEVMA 449
Query: 240 EFAE--RSVAKLEKTIDDLEETLA---SAKEENVEI 270
+ E +S+ KLE +++ +E L S EN E+
Sbjct: 450 QLTESRQSILKLESELENKDEILRDKFSLMNENREL 485
Score = 53.5 bits (127), Expect = 2e-07
Identities = 59/289 (20%), Positives = 123/289 (42%), Gaps = 25/289 (8%)
Query: 5 KKKMQMLKLDKENAIDRAEQAEADKKQAEDRCKQLEEEQQALQKKLKGTEDEVEKYSESV 64
+K+ Q L E + Q EA+ + + Q +Q++L K +
Sbjct: 633 EKERQRLVTGIEELRTKLIQIEAENSDLKVNMAHRTSQFQLIQEELLEKASNSSKLESEM 692
Query: 65 KEAQEKLEQAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLE-EAEKAADES 123
+ +L EK+ + +S+ + +E+EL E++ + + E EK
Sbjct: 693 TKKCSQLLTLEKQLEEKIVAYSSIAAKNAELEQELMEKNEKIRSLETNINTEHEKICLAF 752
Query: 124 ERGMKVIENRAMKDEEKMELQEMQLKEAKHIAEDSDRKYEEVARKLVILEGELERSEERA 183
E+ K+ + + E+++E E QL E D++++E + + +L+ ++ +
Sbjct: 753 EKAKKIHLEQHKEMEKQIERLEAQL-------EKKDQQFKEQEKTMSMLQQDIICKQHHL 805
Query: 184 E-----VAESRARQLEEELRTMDQALKSLMASEEEYSTKEDKYEEEIKLLEEK----LKE 234
E + ES+ +E ++ D+ALK+L E + K + + +++ +E+ L +
Sbjct: 806 ESLDRLLTESKGEMKKENMK-KDEALKALQNQVSEETIKVRQLDSALEICKEELVLHLNQ 864
Query: 235 AETRAEFAERSVAK-------LEKTIDDLEETLASAKEENVEIHQTLDQ 276
E E E+ + K L+K + +L E+NV + TL Q
Sbjct: 865 LEGNKEKFEKQLKKKSEEVYCLQKELKIKNHSLQETSEQNVILQHTLQQ 913
Score = 52.0 bits (123), Expect = 6e-07
Identities = 51/250 (20%), Positives = 115/250 (46%), Gaps = 25/250 (10%)
Query: 29 KKQAEDRCKQLEEEQQALQKKLKGTEDEVEKYSESVKEAQEKLEQAEKKATDAEADVASL 88
K+ E++ L + L + T+ E+EK + +VKE ++ E + T+A L
Sbjct: 1010 KRDGENKAMHLSQLDMILDQ----TKTELEKKTNAVKELEKLQHSTETELTEA------L 1059
Query: 89 NRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIENRAMKDEEKMELQEM-- 146
+R +++E EL A L + L++L+E +++ + +E+ ++++
Sbjct: 1060 QKR-EVLETELQNAHGELKSTLRQLQELRDVLQKAQLSL---------EEKYTTIKDLTA 1109
Query: 147 QLKEAKHIAEDSDRKYEEVARKLVILEGELERSEERAEVAESRARQLEEELRTMDQALKS 206
+L+E K ED ++ E+ + L EL+ +RA + E M+Q +
Sbjct: 1110 ELRECKMEIEDKKQELLEMDQALKERNWELK---QRAAQVTHLDMTIREHRGEMEQKIIK 1166
Query: 207 LMASEEEYSTKEDKYEEEIKLLEEKLKEAETRAEFAERSVAKLEKTIDDLEETLASAKEE 266
L + E+ + + ++I+ L +KL+ A+ + E + + E+ I L++ + ++
Sbjct: 1167 LEGTLEKSELELKECNKQIESLNDKLQNAKEQLREKEFIMLQNEQEISQLKKEIERTQQR 1226
Query: 267 NVEIHQTLDQ 276
E+ + +
Sbjct: 1227 MKEMESVMKE 1236
Score = 32.0 bits (71), Expect = 0.63
Identities = 27/119 (22%), Positives = 54/119 (45%), Gaps = 2/119 (1%)
Query: 10 MLKLDKENAIDRAEQAEADKKQAEDRCKQLEEEQQALQKKLKGTEDEV-EKYSESVKEAQ 68
M +L KE AE + ++ R LE QA KKL + + E Y + Q
Sbjct: 1293 MKQLSKEKDAHGNHLAE-ELGASKVREAHLEARMQAEIKKLSAEVESLKEAYHMEMISHQ 1351
Query: 69 EKLEQAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGM 127
E + + A ++ V LN +++ + EL+ AQ+ ++ Q++++ + + + +
Sbjct: 1352 ENHAKWKISADSQKSSVQQLNEQLEKAKLELEEAQDTVSNLHQQVQDRNEVIEAANEAL 1410
>gi|12667788 myosin, heavy polypeptide 9, non-muscle [Homo sapiens]
Length = 1960
Score = 85.5 bits (210), Expect = 5e-17
Identities = 71/279 (25%), Positives = 129/279 (46%), Gaps = 14/279 (5%)
Query: 2 DAIK--KKMQMLKLDKENAID--RAEQAE--ADKKQAEDRCKQLEEEQQALQKKLKGTED 55
+AIK +K+Q D +D RA + E A K+ E + K +E E LQ++L E
Sbjct: 1635 EAIKQLRKLQAQMKDCMRELDDTRASREEILAQAKENEKKLKSMEAEMIQLQEELAAAER 1694
Query: 56 EVEKYSESVKEAQEKLEQAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEE 115
+ + E +++ + K A + L RI +EEEL+ Q +L++
Sbjct: 1695 AKRQAQQERDELADEIANSSGKGALALEEKRRLEARIAQLEEELEEEQGNTELINDRLKK 1754
Query: 116 AEKAADESERGMKVIENRAMKDEEKMELQEMQLKEAKHIAEDSD----RKYEE----VAR 167
A D+ + + + A K+E + E Q KE K ++ + KY+ +
Sbjct: 1755 ANLQIDQINTDLNLERSHAQKNENARQQLERQNKELKVKLQEMEGTVKSKYKASITALEA 1814
Query: 168 KLVILEGELERSEERAEVAESRARQLEEELRTMDQALKSLMASEEEYSTKEDKYEEEIKL 227
K+ LE +L+ + + A + R+ E++L+ + + + E+Y + DK +K
Sbjct: 1815 KIAQLEEQLDNETKERQAACKQVRRTEKKLKDVLLQVDDERRNAEQYKDQADKASTRLKQ 1874
Query: 228 LEEKLKEAETRAEFAERSVAKLEKTIDDLEETLASAKEE 266
L+ +L+EAE A+ A S KL++ ++D ET + E
Sbjct: 1875 LKRQLEEAEEEAQRANASRRKLQRELEDATETADAMNRE 1913
Score = 82.4 bits (202), Expect = 4e-16
Identities = 77/303 (25%), Positives = 138/303 (45%), Gaps = 25/303 (8%)
Query: 1 MDAIKKKMQMLKLDKENAIDRAEQA----EADKKQAEDRCKQLEEEQQALQ-------KK 49
+ A KKKMQ + E ++ E A + +K E + K+LEEEQ L+ K+
Sbjct: 934 LQAEKKKMQQNIQELEEQLEEEESARQKLQLEKVTTEAKLKKLEEEQIILEDQNCKLAKE 993
Query: 50 LKGTEDEVEKYSESVKEAQEKLEQAEKKATDAEADVASLNRRIQLVE---EELDRAQERL 106
K ED + +++ ++ E +EK + K EA + L R++ E +EL++ + +L
Sbjct: 994 KKLLEDRIAEFTTNLTEEEEKSKSLAKLKNKHEAMITDLEERLRREEKQRQELEKTRRKL 1053
Query: 107 ATALQKLEE--AEKAADESERGMKVIENRAMKDEEKMELQEMQLKEAKHIAEDSDRKYEE 164
L + AE A +E M++ K EE+++ +++E + +K E
Sbjct: 1054 EGDSTDLSDQIAELQAQIAELKMQL-----AKKEEELQAALARVEEEAAQKNMALKKIRE 1108
Query: 165 VARKLVILEGELERSEERAEVAESRARQLEEELRTMDQALKSLMASEEEYSTKEDKYEEE 224
+ ++ L+ +LE AE + R L EEL + L+ + S K E+E
Sbjct: 1109 LESQISELQEDLESERASRNKAEKQKRDLGEELEALKTELEDTLDSTAAQQELRSKREQE 1168
Query: 225 IKLLEEKL-KEAETRAEFAERSVAKLEKTIDDLEETLASAKEENVEIH---QTLDQTLLE 280
+ +L++ L +EA+T + K + +++L E L K + QTL+ E
Sbjct: 1169 VNILKKTLEEEAKTHEAQIQEMRQKHSQAVEELAEQLEQTKRVKANLEKAKQTLENERGE 1228
Query: 281 LNN 283
L N
Sbjct: 1229 LAN 1231
Score = 73.6 bits (179), Expect = 2e-13
Identities = 67/292 (22%), Positives = 135/292 (46%), Gaps = 21/292 (7%)
Query: 6 KKMQMLKLDKENAIDRAEQAEADKKQAEDRCKQLEEEQQALQKKLKGTEDEVEKYSESVK 65
KK++ L+ + E A + +AE + + L EE +AL+ +L+ T D E
Sbjct: 1104 KKIRELESQISELQEDLESERASRNKAEKQKRDLGEELEALKTELEDTLDSTAAQQELRS 1163
Query: 66 EAQEKL----EQAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAAD 121
+ ++++ + E++A EA + + ++ EEL E+ LE+A++
Sbjct: 1164 KREQEVNILKKTLEEEAKTHEAQIQEMRQKHSQAVEELAEQLEQTKRVKANLEKAKQTL- 1222
Query: 122 ESERG-----MKVIENRAMKDEEKMELQEMQLKEAKHIAEDSDRKYEEVARKLVILEGEL 176
E+ERG +KV+ E K + E QL+E + + +R E+A K+ L+ EL
Sbjct: 1223 ENERGELANEVKVLLQGKGDSEHKRKKVEAQLQELQVKFNEGERVRTELADKVTKLQVEL 1282
Query: 177 ERSEERAEVAESRARQLEEELRTMDQALKSLMASEEE-------YSTKEDKYEEEIKLLE 229
+ ++S++ +L ++ ++ L+ +E STK + E+E
Sbjct: 1283 DNVTGLLSQSDSKSSKLTKDFSALESQLQDTQELLQEENRQKLSLSTKLKQVEDEKNSFR 1342
Query: 230 EKLKEAETRAEFAERSVAKLEKTIDDLEETLASAKEENVEIHQTLDQTLLEL 281
E+L+E E E+ +A L + D+++ + E++V +T ++ +L
Sbjct: 1343 EQLEEEEEAKHNLEKQIATLHAQVADMKKKM----EDSVGCLETAEEVKRKL 1390
Score = 72.8 bits (177), Expect = 3e-13
Identities = 59/302 (19%), Positives = 146/302 (48%), Gaps = 19/302 (6%)
Query: 1 MDAIKKKMQMLKLDKENAIDRAEQAEADKKQAEDRCKQLEEEQQALQKKLKGTEDEVEKY 60
++ K ++Q D +D Q+ + ++ + + QL E++ + K D E
Sbjct: 1411 LEKTKTRLQQELDDLLVDLDHQRQSACNLEKKQKKFDQLLAEEKTISAKYAEERDRAEAE 1470
Query: 61 SESVKEAQEKLEQAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAA 120
+ + L +A ++A + +A++ LN++ + E+L +++ + ++ +LE++++A
Sbjct: 1471 AREKETKALSLARALEEAMEQKAELERLNKQFRTEMEDLMSSKDDVGKSVHELEKSKRAL 1530
Query: 121 DESERGMKV----IENRAMKDEE-----KMELQEMQLKEAKHIA---EDSDRKYEEVARK 168
++ MK +E+ E+ ++ LQ M+ + + + E S+ K +++ R+
Sbjct: 1531 EQQVEEMKTQLEELEDELQATEDAKLRLEVNLQAMKAQFERDLQGRDEQSEEKKKQLVRQ 1590
Query: 169 LVILEGELERSEERAEVAESRARQLEEELRTMDQALKSLMASEEEYSTKEDKYEEEIKLL 228
+ +E ELE ++ +A + ++LE +L+ ++ + S + +E + K + ++K
Sbjct: 1591 VREMEAELEDERKQRSMAVAARKKLEMDLKDLEAHIDSANKNRDEAIKQLRKLQAQMKDC 1650
Query: 229 EEKL-------KEAETRAEFAERSVAKLEKTIDDLEETLASAKEENVEIHQTLDQTLLEL 281
+L +E +A+ E+ + +E + L+E LA+A+ + Q D+ E+
Sbjct: 1651 MRELDDTRASREEILAQAKENEKKLKSMEAEMIQLQEELAAAERAKRQAQQERDELADEI 1710
Query: 282 NN 283
N
Sbjct: 1711 AN 1712
Score = 70.5 bits (171), Expect = 2e-12
Identities = 64/277 (23%), Positives = 132/277 (47%), Gaps = 27/277 (9%)
Query: 7 KMQMLKLDKENAIDRAE----QAEADKKQAEDRCK---QLEEEQQALQKKLKGTEDEVEK 59
K++ +L EN + E Q A+K Q +++ + +L E + L+ +L + E+E
Sbjct: 856 KVREKQLAAENRLTEMETLQSQLMAEKLQLQEQLQAETELCAEAEELRARLTAKKQELE- 914
Query: 60 YSESVKEAQEKLEQAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKA 119
E + + ++E+ E++ +A+ + + IQ +EE+L+ + +A QKL + EK
Sbjct: 915 --EICHDLEARVEEEEERCQHLQAEKKKMQQNIQELEEQLEEEE----SARQKL-QLEKV 967
Query: 120 ADES-----ERGMKVIENRAMKDEEKMELQEMQLKEAKHIAEDSDRKYEEVAR------- 167
E+ E ++E++ K ++ +L E ++ E + + K + +A+
Sbjct: 968 TTEAKLKKLEEEQIILEDQNCKLAKEKKLLEDRIAEFTTNLTEEEEKSKSLAKLKNKHEA 1027
Query: 168 KLVILEGELERSEERAEVAESRARQLEEELRTMDQALKSLMASEEEYSTKEDKYEEEIKL 227
+ LE L R E++ + E R+LE + + + L A E + K EEE++
Sbjct: 1028 MITDLEERLRREEKQRQELEKTRRKLEGDSTDLSDQIAELQAQIAELKMQLAKKEEELQA 1087
Query: 228 LEEKLKEAETRAEFAERSVAKLEKTIDDLEETLASAK 264
+++E + A + + +LE I +L+E L S +
Sbjct: 1088 ALARVEEEAAQKNMALKKIRELESQISELQEDLESER 1124
Score = 67.0 bits (162), Expect = 2e-11
Identities = 63/274 (22%), Positives = 127/274 (46%), Gaps = 31/274 (11%)
Query: 11 LKLDKENAIDRAEQAEADKKQAEDRCKQLEEEQQALQKKLKGTEDEVEKYSESVKEAQ-- 68
L K+ + EA ++ E+RC+ L+ E++ +Q+ ++ E+++E+ + ++ Q
Sbjct: 906 LTAKKQELEEICHDLEARVEEEEERCQHLQAEKKKMQQNIQELEEQLEEEESARQKLQLE 965
Query: 69 -----EKLEQAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADES 123
KL++ E++ E L + +L+E+ + L +K + K ++
Sbjct: 966 KVTTEAKLKKLEEEQIILEDQNCKLAKEKKLLEDRIAEFTTNLTEEEEKSKSLAKLKNKH 1025
Query: 124 ERGMKVIENRAMKDEEKMELQEMQLKEAKHIAEDSDRKYEEVARKLVILEGELERSEERA 183
E + +E R ++E++ + E ++ + + D + E+ ++ L+ +L + EE
Sbjct: 1026 EAMITDLEERLRREEKQRQELEKTRRKLEGDSTDLSDQIAELQAQIAELKMQLAKKEEEL 1085
Query: 184 EVAESRARQLEEELRTMDQALKSLMASEEEYSTKEDKYEEEIKLLEEKLKEAETRAEFAE 243
+ A +R +EEE + ALK + + E +I L+E L+ +E A
Sbjct: 1086 QAALAR---VEEEAAQKNMALKKIR-----------ELESQISELQEDLE-----SERAS 1126
Query: 244 RSVAKLEKTIDDLEETLASAKEENVEIHQTLDQT 277
R+ K EK DL E L + K E+ TLD T
Sbjct: 1127 RN--KAEKQKRDLGEELEALK---TELEDTLDST 1155
Score = 64.7 bits (156), Expect = 9e-11
Identities = 66/266 (24%), Positives = 118/266 (44%), Gaps = 32/266 (12%)
Query: 29 KKQAEDRCKQLEEEQQ---ALQKKLKGTEDEVEKYSESVKEAQEKLEQAEKKATDAEADV 85
+ Q +D + L+EE + +L KLK EDE + E ++E +E EK+ A V
Sbjct: 1307 ESQLQDTQELLQEENRQKLSLSTKLKQVEDEKNSFREQLEEEEEAKHNLEKQIATLHAQV 1366
Query: 86 ASLNRR-------IQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIENR----- 133
A + ++ ++ EE + Q+ L Q+ EE A D+ E+ ++
Sbjct: 1367 ADMKKKMEDSVGCLETAEEVKRKLQKDLEGLSQRHEEKVAAYDKLEKTKTRLQQELDDLL 1426
Query: 134 ---------AMKDEEKMELQEMQLKEAKHI----AEDSDRKYEEVARKLVILEGELERSE 180
A E+K + + L E K I AE+ DR E AR+ L R+
Sbjct: 1427 VDLDHQRQSACNLEKKQKKFDQLLAEEKTISAKYAEERDRA-EAEAREKETKALSLARAL 1485
Query: 181 ERAEVAESRARQLEEELRTMDQALKSLMASEEEYSTKEDKYEEEIKLLEEKLKEAETRAE 240
E A ++ +L ++ RT ++ LM+S+++ + E+ + LE++++E +T+ E
Sbjct: 1486 EEAMEQKAELERLNKQFRT---EMEDLMSSKDDVGKSVHELEKSKRALEQQVEEMKTQLE 1542
Query: 241 FAERSVAKLEKTIDDLEETLASAKEE 266
E + E LE L + K +
Sbjct: 1543 ELEDELQATEDAKLRLEVNLQAMKAQ 1568
Score = 64.3 bits (155), Expect = 1e-10
Identities = 57/249 (22%), Positives = 117/249 (46%), Gaps = 21/249 (8%)
Query: 47 QKKLKGTEDEVEKYSESVKEAQEKLEQAEKKATDAEADVASLNRRIQLVEEELDRAQERL 106
++++ E+E+ K E A+ +L + E + A+ L ++Q E A+E
Sbjct: 844 EEEMMAKEEELVKVREKQLAAENRLTEMETLQSQLMAEKLQLQEQLQAETELCAEAEELR 903
Query: 107 ATALQKLEEAEKAADESERGMKVIENRAMKDEEK-----MELQEMQ--LKEAKHIAEDSD 159
A K +E E+ + +E R ++EE+ E ++MQ ++E + E+ +
Sbjct: 904 ARLTAKKQELEEICHD-------LEARVEEEEERCQHLQAEKKKMQQNIQELEEQLEEEE 956
Query: 160 RKYEEVARKLVILEGELERSEERAEVAESRARQLEEELRTMDQALKSLMA--SEEEYSTK 217
+++ + V E +L++ EE + E + +L +E + ++ + +EEE +K
Sbjct: 957 SARQKLQLEKVTTEAKLKKLEEEQIILEDQNCKLAKEKKLLEDRIAEFTTNLTEEEEKSK 1016
Query: 218 -----EDKYEEEIKLLEEKLKEAETRAEFAERSVAKLEKTIDDLEETLASAKEENVEIHQ 272
++K+E I LEE+L+ E + + E++ KLE DL + +A + + E+
Sbjct: 1017 SLAKLKNKHEAMITDLEERLRREEKQRQELEKTRRKLEGDSTDLSDQIAELQAQIAELKM 1076
Query: 273 TLDQTLLEL 281
L + EL
Sbjct: 1077 QLAKKEEEL 1085
Score = 63.5 bits (153), Expect = 2e-10
Identities = 64/272 (23%), Positives = 120/272 (44%), Gaps = 9/272 (3%)
Query: 4 IKKKMQMLKLDKENAID-RAEQAEADKKQAEDRCKQLEEEQQALQKKLKGTEDEVEKYSE 62
++ +Q +K E + R EQ+E KKQ + +++E E + +K+ +K
Sbjct: 1558 LEVNLQAMKAQFERDLQGRDEQSEEKKKQLVRQVREMEAELEDERKQRSMAVAARKKLEM 1617
Query: 63 SVKEAQEKLEQAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADE 122
+K+ + ++ A K +A + L +++ ELD + L + +E EK
Sbjct: 1618 DLKDLEAHIDSANKNRDEAIKQLRKLQAQMKDCMRELDDTRASREEILAQAKENEKKLKS 1677
Query: 123 SERGM-KVIENRAMKDEEKMELQEMQLKEAKHIAEDSDR---KYEEVAR---KLVILEGE 175
E M ++ E A + K + Q+ + + A IA S + EE R ++ LE E
Sbjct: 1678 MEAEMIQLQEELAAAERAKRQAQQERDELADEIANSSGKGALALEEKRRLEARIAQLEEE 1737
Query: 176 LERSEERAEVAESRARQLEEELRTMDQALKSLMASEEEYSTKEDKYEEEIKLLEEKLKEA 235
LE + E+ R ++ ++ ++ L + ++ + E + K L+ KL+E
Sbjct: 1738 LEEEQGNTELINDRLKKANLQIDQINTDLNLERSHAQKNENARQQLERQNKELKVKLQEM 1797
Query: 236 E-TRAEFAERSVAKLEKTIDDLEETLASAKEE 266
E T + S+ LE I LEE L + +E
Sbjct: 1798 EGTVKSKYKASITALEAKIAQLEEQLDNETKE 1829
Score = 62.8 bits (151), Expect = 3e-10
Identities = 61/287 (21%), Positives = 133/287 (46%), Gaps = 22/287 (7%)
Query: 4 IKKKMQMLKLDKENAIDRAEQAEADKKQAEDRCKQLEEEQQAL----QKKLKGTEDEVEK 59
++K + L+ E + E+ E + + ED +LE QA+ ++ L+G +++ E+
Sbjct: 1523 LEKSKRALEQQVEEMKTQLEELEDELQATEDAKLRLEVNLQAMKAQFERDLQGRDEQSEE 1582
Query: 60 YSES----VKEAQEKLEQAEKKATDA-------EADVASLNRRIQLVEEELDRAQERLAT 108
+ V+E + +LE K+ + A E D+ L I + D A ++L
Sbjct: 1583 KKKQLVRQVREMEAELEDERKQRSMAVAARKKLEMDLKDLEAHIDSANKNRDEAIKQLRK 1642
Query: 109 ALQKLEEAEKAADESERGMKVIENRAMKDEEK---MELQEMQLKEAKHIAEDSDRKYE-- 163
++++ + D++ + I +A ++E+K ME + +QL+E AE + R+ +
Sbjct: 1643 LQAQMKDCMRELDDTRASREEILAQAKENEKKLKSMEAEMIQLQEELAAAERAKRQAQQE 1702
Query: 164 --EVARKLVILEGELERSEERAEVAESRARQLEEELRTMDQALKSLMASEEEYSTKEDKY 221
E+A ++ G+ + E E+R QLEEEL + + ++ + + D+
Sbjct: 1703 RDELADEIANSSGKGALALEEKRRLEARIAQLEEELEEEQGNTELINDRLKKANLQIDQI 1762
Query: 222 EEEIKLLEEKLKEAETRAEFAERSVAKLEKTIDDLEETLASAKEENV 268
++ L ++ E + ER +L+ + ++E T+ S + ++
Sbjct: 1763 NTDLNLERSHAQKNENARQQLERQNKELKVKLQEMEGTVKSKYKASI 1809
Score = 62.0 bits (149), Expect = 6e-10
Identities = 71/288 (24%), Positives = 136/288 (47%), Gaps = 43/288 (14%)
Query: 4 IKKKMQMLKLDKENAIDRAEQAEADKKQAEDRCKQLEEEQQALQKKLKGTEDEVEKYSES 63
+KKKM+ D ++ AE+ + ++ + Q EE+ A KL+ T+ +++ +
Sbjct: 1369 MKKKME----DSVGCLETAEEVKRKLQKDLEGLSQRHEEKVAAYDKLEKTKTRLQQELDD 1424
Query: 64 V-------KEAQEKLEQAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEA 116
+ +++ LE+ +KK A+ +++ + EE DRA+ A A +K +A
Sbjct: 1425 LLVDLDHQRQSACNLEKKQKKFDQLLAEEKTISAKYA---EERDRAE---AEAREKETKA 1478
Query: 117 EKAADESERGMKVIENRAMKDEEKMELQEMQLKEAKHIAEDSDRKYEEVARKLVILEGEL 176
A E M E+K EL+ + K+ + ED ++V + + LE
Sbjct: 1479 LSLARALEEAM----------EQKAELERLN-KQFRTEMEDLMSSKDDVGKSVHELEKSK 1527
Query: 177 ERSEERAEVAESRARQLEEELRTMDQA-------LKSLMAS-EEEYSTKEDKYEEEIKLL 228
E++ E +++ +LE+EL+ + A L+++ A E + ++++ EE+ K L
Sbjct: 1528 RALEQQVEEMKTQLEELEDELQATEDAKLRLEVNLQAMKAQFERDLQGRDEQSEEKKKQL 1587
Query: 229 EEKLK--EAETRAEFAERSVA-----KLEKTIDDLEETLASAKEENVE 269
+++ EAE E +RS+A KLE + DLE + SA + E
Sbjct: 1588 VRQVREMEAELEDERKQRSMAVAARKKLEMDLKDLEAHIDSANKNRDE 1635
Score = 59.7 bits (143), Expect = 3e-09
Identities = 69/317 (21%), Positives = 150/317 (47%), Gaps = 45/317 (14%)
Query: 6 KKMQMLKLDKENAIDR--AEQAEADKKQAEDRC--KQLEEEQQALQKKLKGTEDEVEKYS 61
++++ LK + E+ +D A+Q K++ E K LEEE + + ++ ++ +K+S
Sbjct: 1139 EELEALKTELEDTLDSTAAQQELRSKREQEVNILKKTLEEEAKTHEAQI---QEMRQKHS 1195
Query: 62 ESVKEAQEKLEQAEKKATDAEADVASL-NRRIQLVEE---------ELDRAQERLATALQ 111
++V+E E+LEQ ++ + E +L N R +L E + + ++++ LQ
Sbjct: 1196 QAVEELAEQLEQTKRVKANLEKAKQTLENERGELANEVKVLLQGKGDSEHKRKKVEAQLQ 1255
Query: 112 KLE----EAEKA----ADESERGMKVIEN----------RAMKDEEKMELQEMQLKEAKH 153
+L+ E E+ AD+ + ++N ++ K + E QL++ +
Sbjct: 1256 ELQVKFNEGERVRTELADKVTKLQVELDNVTGLLSQSDSKSSKLTKDFSALESQLQDTQE 1315
Query: 154 IAEDSDRKYEEVARKLVILEGELERSEERAEVAESRARQLEEELRTMDQALKSLMASEEE 213
+ ++ +R+ ++ KL +E E E+ E E LE+++ T+ + + E+
Sbjct: 1316 LLQEENRQKLSLSTKLKQVEDEKNSFREQLEEEEEAKHNLEKQIATLHAQVADMKKKMED 1375
Query: 214 ----YSTKED---KYEEEIKLLEEKLKEAETRAEFAERSVAKLEKTIDDLEETLASAKEE 266
T E+ K +++++ L ++ +E + E++ +L++ +DDL L ++
Sbjct: 1376 SVGCLETAEEVKRKLQKDLEGLSQRHEEKVAAYDKLEKTKTRLQQELDDLLVDLDHQRQS 1435
Query: 267 --NVEIHQ-TLDQTLLE 280
N+E Q DQ L E
Sbjct: 1436 ACNLEKKQKKFDQLLAE 1452
Score = 55.5 bits (132), Expect = 5e-08
Identities = 62/270 (22%), Positives = 113/270 (41%), Gaps = 13/270 (4%)
Query: 25 AEADKKQAEDRCKQLEEEQQALQKKLKGTEDEVEKYSESVKEAQEKLEQAEKKATDAEAD 84
+E +K+ E + ++L+ + ++ D+V K + L Q++ K++ D
Sbjct: 1243 SEHKRKKVEAQLQELQVKFNEGERVRTELADKVTKLQVELDNVTGLLSQSDSKSSKLTKD 1302
Query: 85 VASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIENRAMKDEEKMELQ 144
++L ++Q +E L + + KL++ E + ++ E E+++
Sbjct: 1303 FSALESQLQDTQELLQEENRQKLSLSTKLKQVEDEKNSFREQLEEEEEAKHNLEKQIATL 1362
Query: 145 EMQLKEAKHIAEDSD---RKYEEVARKL-VILEGELERSEERA---EVAESRARQLEEEL 197
Q+ + K EDS EEV RKL LEG +R EE+ + E +L++EL
Sbjct: 1363 HAQVADMKKKMEDSVGCLETAEEVKRKLQKDLEGLSQRHEEKVAAYDKLEKTKTRLQQEL 1422
Query: 198 RTMDQALKSLMASEEEYSTKEDKYEE---EIKLLEEKLKEAETRAEFAERSVAKLEKTID 254
+ L S K+ K+++ E K + K E RAE R + E
Sbjct: 1423 DDLLVDLDHQRQSACNLEKKQKKFDQLLAEEKTISAKYAEERDRAEAEAR---EKETKAL 1479
Query: 255 DLEETLASAKEENVEIHQTLDQTLLELNNL 284
L L A E+ E+ + Q E+ +L
Sbjct: 1480 SLARALEEAMEQKAELERLNKQFRTEMEDL 1509
Score = 55.1 bits (131), Expect = 7e-08
Identities = 46/228 (20%), Positives = 101/228 (44%), Gaps = 22/228 (9%)
Query: 17 NAIDRAEQAEADKKQAEDRCKQLEEE-------QQALQKKLKGTEDEVEKYSESVKEAQE 69
N+ + A +K++ E R QLEEE + + +LK ++++ + + +
Sbjct: 1712 NSSGKGALALEEKRRLEARIAQLEEELEEEQGNTELINDRLKKANLQIDQINTDLNLERS 1771
Query: 70 KLEQAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQ-KLEEAEKAADESERGMK 128
++ E E L ++Q +E + + TAL+ K+ + E+ D + +
Sbjct: 1772 HAQKNENARQQLERQNKELKVKLQEMEGTVKSKYKASITALEAKIAQLEEQLDNETKERQ 1831
Query: 129 VIENRAMKDEEKMELQEMQLKEAKHIAEDSDRKYEEVARKLVILEGELERSEERAEVAES 188
+ + E+K++ +Q+ + + AE + ++ + +L L+ +LE +EE A+ A +
Sbjct: 1832 AACKQVRRTEKKLKDVLLQVDDERRNAEQYKDQADKASTRLKQLKRQLEEAEEEAQRANA 1891
Query: 189 RARQLEEELRTMDQALKSLMASEEEYSTKEDKYEEEIKLLEEKLKEAE 236
R+L+ EL E+ + D E+ L+ KL+ +
Sbjct: 1892 SRRKLQREL--------------EDATETADAMNREVSSLKNKLRRGD 1925
Score = 50.4 bits (119), Expect = 2e-06
Identities = 39/187 (20%), Positives = 91/187 (48%), Gaps = 3/187 (1%)
Query: 7 KMQMLKLDKENAIDRAEQAEADKKQAEDRCKQLEEEQQALQKKLKGTEDEVE-KYSESVK 65
K L++D+ N E++ A K E+ +QLE + + L+ KL+ E V+ KY S+
Sbjct: 1753 KKANLQIDQINTDLNLERSHAQKN--ENARQQLERQNKELKVKLQEMEGTVKSKYKASIT 1810
Query: 66 EAQEKLEQAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESER 125
+ K+ Q E++ + + + ++++ E++L ++ + E+ + AD++
Sbjct: 1811 ALEAKIAQLEEQLDNETKERQAACKQVRRTEKKLKDVLLQVDDERRNAEQYKDQADKAST 1870
Query: 126 GMKVIENRAMKDEEKMELQEMQLKEAKHIAEDSDRKYEEVARKLVILEGELERSEERAEV 185
+K ++ + + EE+ + ++ + ED+ + + R++ L+ +L R + V
Sbjct: 1871 RLKQLKRQLEEAEEEAQRANASRRKLQRELEDATETADAMNREVSSLKNKLRRGDLPFVV 1930
Query: 186 AESRARQ 192
AR+
Sbjct: 1931 PRRMARK 1937
Score = 36.6 bits (83), Expect = 0.026
Identities = 23/89 (25%), Positives = 48/89 (53%), Gaps = 7/89 (7%)
Query: 5 KKKMQMLKLDKENAIDRAEQAEADKKQAEDRCKQLEEEQQALQKKLKGTEDEVEKYSESV 64
+KK++ + L ++ AEQ + +A R KQ L+++L+ E+E ++ + S
Sbjct: 1841 EKKLKDVLLQVDDERRNAEQYKDQADKASTRLKQ-------LKRQLEEAEEEAQRANASR 1893
Query: 65 KEAQEKLEQAEKKATDAEADVASLNRRIQ 93
++ Q +LE A + A +V+SL +++
Sbjct: 1894 RKLQRELEDATETADAMNREVSSLKNKLR 1922
Score = 29.3 bits (64), Expect = 4.1
Identities = 13/75 (17%), Positives = 36/75 (48%)
Query: 1 MDAIKKKMQMLKLDKENAIDRAEQAEADKKQAEDRCKQLEEEQQALQKKLKGTEDEVEKY 60
+D ++ + K + A R +Q + ++AE+ ++ ++ LQ++L+ + +
Sbjct: 1851 VDDERRNAEQYKDQADKASTRLKQLKRQLEEAEEEAQRANASRRKLQRELEDATETADAM 1910
Query: 61 SESVKEAQEKLEQAE 75
+ V + KL + +
Sbjct: 1911 NREVSSLKNKLRRGD 1925
>gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo
sapiens]
Length = 750
Score = 85.1 bits (209), Expect = 6e-17
Identities = 69/293 (23%), Positives = 143/293 (48%), Gaps = 22/293 (7%)
Query: 2 DAIKKKMQMLKLDKENAIDRAEQAEADKKQAEDRCKQLEEEQQALQKKLKGTEDEVEKYS 61
+ ++++ +M+ +E + E+ +K E K+ EEE+ Q+K + E ++ +
Sbjct: 377 EKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQE 436
Query: 62 ESVKEAQEKLEQAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAAD 121
E ++E +EK+ + EKK E ++ + ++ EEE + QE + +K+ E E+
Sbjct: 437 EKIREQEEKIREQEKKMWRQE---EKIHEQEKIREEEKRQEQEEMWRQEEKIHEQEEIWR 493
Query: 122 ESERGMKVIENRAMKDEEKMELQEMQLKEAKHIAEDSDRK---YEEVARKLVILEGELER 178
+ E+ M E + K EEK+ QE +++E + + + K EE R+ + E E+
Sbjct: 494 QKEK-MHEQEEKIRKQEEKVWRQEEKIREQEEKIREQEEKMWRQEEKIREQEEMWREEEK 552
Query: 179 SEERAEVAESRARQ--------LEEELRTMDQAL----KSLMASEEEYSTKED---KYEE 223
E+ ++ E RQ EE++R ++ + + + EE+ +E+ K EE
Sbjct: 553 MHEQEKIWEEEKRQEQEDKMWRQEEKIREQEEKVWRQEEKIREQEEKRQEQEEKMWKQEE 612
Query: 224 EIKLLEEKLKEAETRAEFAERSVAKLEKTIDDLEETLASAKEENVEIHQTLDQ 276
+I+ EEK++E E + E + + E+ + EE + +E+ E + + +
Sbjct: 613 KIREQEEKIQEQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQE 665
Score = 82.8 bits (203), Expect = 3e-16
Identities = 57/249 (22%), Positives = 123/249 (49%), Gaps = 12/249 (4%)
Query: 23 EQAEADKKQAEDRCKQLEEEQQALQKKLKGTEDEVEKYSESVKEAQEKLEQAEK------ 76
EQ E +KQ E +Q EE+ + ++K++ E+++ + E ++E +E + EK
Sbjct: 500 EQEEKIRKQEEKVWRQ-EEKIREQEEKIREQEEKMWRQEEKIREQEEMWREEEKMHEQEK 558
Query: 77 -----KATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIE 131
K + E + +I+ EE++ R +E++ +K +E E+ + E ++ E
Sbjct: 559 IWEEEKRQEQEDKMWRQEEKIREQEEKVWRQEEKIREQEEKRQEQEEKMWKQEEKIREQE 618
Query: 132 NRAMKDEEKMELQEMQLKEAKHIAEDSDRKYEEVARKLVILEGELERSEERAEVAESRAR 191
+ + EEK+ QE +++E + + ++ + K E K+ E +++ EE E + R
Sbjct: 619 EKIQEQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEETMWRQEEKIR 678
Query: 192 QLEEELRTMDQALKSLMASEEEYSTKEDKYEEEIKLLEEKLKEAETRAEFAERSVAKLEK 251
+ E+++R ++ ++ +E K + EE++ EEK++E E + E + + E
Sbjct: 679 EQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEV 738
Query: 252 TIDDLEETL 260
+ EE +
Sbjct: 739 RLRQQEEKM 747
Score = 79.3 bits (194), Expect = 3e-15
Identities = 59/280 (21%), Positives = 135/280 (48%), Gaps = 29/280 (10%)
Query: 14 DKENAIDRAEQAEADKKQAEDRCKQLEEEQQALQKKLKGTEDEVEKYSESVKEAQEKLEQ 73
++E + R E+ ++++ + K+ E+E+ Q++ ++E+ + E + E +EK+ +
Sbjct: 448 EQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIHEQEEIWRQKEKMHEQEEKIRK 507
Query: 74 AEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQ------KLEEAEKAADESERGM 127
E+K E + +I+ EE++ R +E++ + K+ E EK +E +R
Sbjct: 508 QEEKVWRQEEKIREQEEKIREQEEKMWRQEEKIREQEEMWREEEKMHEQEKIWEEEKRQE 567
Query: 128 KVIENRAMKDEEKMELQEMQLKEAKHIAEDSDRKYEEVARKLVILEGELERSEERAEVAE 187
+ E++ + EEK+ QE ++ + + + K +E K+ E ++ EE+ + E
Sbjct: 568 Q--EDKMWRQEEKIREQEEKVWRQEEKIREQEEKRQEQEEKMWKQEEKIREQEEKIQEQE 625
Query: 188 SRARQLEEELRTMDQALKS----LMASEEEYSTKEDKYEEE-----------------IK 226
+ R+ EE++R ++ + + EE+ +E+K +E+ I+
Sbjct: 626 EKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEETMWRQEEKIREQEKKIR 685
Query: 227 LLEEKLKEAETRAEFAERSVAKLEKTIDDLEETLASAKEE 266
EEK++E E + E + + E+ + + EE + +E+
Sbjct: 686 EQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEK 725
Score = 79.0 bits (193), Expect = 5e-15
Identities = 59/282 (20%), Positives = 142/282 (50%), Gaps = 22/282 (7%)
Query: 5 KKKMQMLKLDKENAIDRAEQAEADKKQAEDRCKQLEEEQQALQKKLKGTEDEVEKYSESV 64
+K+ ++ +L+++ + + +K+Q E++ ++ +E++Q + K+ E+++ + E +
Sbjct: 388 EKEEKIRELEEKMHEQEKIREQEEKRQEEEKIRE-QEKRQEQEAKMWRQEEKIREQEEKI 446
Query: 65 KEAQEKLEQAEKKATDAEADVASLNRRIQLV----------EEELDRAQERLATALQKLE 114
+E ++K+ + E+K + E R+ Q +EE+ R +E++ +K+
Sbjct: 447 REQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIHEQEEIWRQKEKMHEQEEKIR 506
Query: 115 EAEKAADESERGMKVIENRAMKDEEKMELQEMQLKEAKHIAEDSDRKYEEVA----RKLV 170
+ E+ E ++ E + + EEKM QE +++E + + + ++ +E+ K
Sbjct: 507 KQEEKVWRQEEKIREQEEKIREQEEKMWRQEEKIREQEEMWREEEKMHEQEKIWEEEKRQ 566
Query: 171 ILEGELERSEERAEVAESRARQLEEELRTMDQALKS----LMASEEEYSTKEDKY---EE 223
E ++ R EE+ E + + EE++R ++ + + EE+ +E+K EE
Sbjct: 567 EQEDKMWRQEEKIREQEEKVWRQEEKIREQEEKRQEQEEKMWKQEEKIREQEEKIQEQEE 626
Query: 224 EIKLLEEKLKEAETRAEFAERSVAKLEKTIDDLEETLASAKE 265
+I+ EEK++E E + E + + E+ + + EE + +E
Sbjct: 627 KIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEE 668
Score = 79.0 bits (193), Expect = 5e-15
Identities = 51/235 (21%), Positives = 114/235 (48%), Gaps = 11/235 (4%)
Query: 2 DAIKKKMQMLKLDKENAIDRAEQAEADKKQAEDRCKQLEEEQQALQKKLKGTEDEVEKYS 61
+ I+++ + + +E ++ E ++K E EE++Q + K+ E+++ +
Sbjct: 524 EKIREQEEKMWRQEEKIREQEEMWREEEKMHEQEKIWEEEKRQEQEDKMWRQEEKIREQE 583
Query: 62 ESVKEAQEKLEQAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAAD 121
E V +EK+ + E+K + E + +I+ EE++ +E++ +K+ E E+
Sbjct: 584 EKVWRQEEKIREQEEKRQEQEEKMWKQEEKIREQEEKIQEQEEKIREQEEKIREQEEMTQ 643
Query: 122 ESERGMKVIENRAMKDEEKMELQEMQLKEAKHIAEDSDRKYEEVARKLVILEGELERSEE 181
E E M E + + EEKM+ QE + + + ++K E K+ E ++ EE
Sbjct: 644 EQEEKMGEQEEKMCEQEEKMQEQEETMWRQEEKIREQEKKIREQEEKIREQEEMMQEQEE 703
Query: 182 RAEVAESRARQLEEELRTMDQALKSLMASEEEYSTKEDKYEEEIKL--LEEKLKE 234
+ E + + EE+++ ++ ++ +E +E+E++L EEK++E
Sbjct: 704 KMWEQEEKMCEQEEKMQEQEEKMRR---------QEEKMWEQEVRLRQQEEKMQE 749
Score = 78.6 bits (192), Expect = 6e-15
Identities = 64/275 (23%), Positives = 133/275 (48%), Gaps = 21/275 (7%)
Query: 6 KKMQMLKLDKENAIDRAEQAEADKKQAEDRCKQLEEEQQALQKKLKGTEDEVEKYSESVK 65
++ + + +KE + R E+ +K E++ ++ EE ++K++ E+ + + E ++
Sbjct: 338 RRQEEMMWEKEEKMRRQEEMMWEK---EEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIR 394
Query: 66 EAQEKLEQAEK-----KATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAA 120
E +EK+ + EK + E + +R Q E ++ R +E++ +K+ E EK
Sbjct: 395 ELEEKMHEQEKIREQEEKRQEEEKIREQEKR-QEQEAKMWRQEEKIREQEEKIREQEKKM 453
Query: 121 DESERGMKVIENRAMKDEEKMELQEMQLKEAKHIAEDSD-----RKYEEVARKLVILEGE 175
E K+ E +++EEK + QE ++ + I E + K E K+ E +
Sbjct: 454 WRQEE--KIHEQEKIREEEKRQEQEEMWRQEEKIHEQEEIWRQKEKMHEQEEKIRKQEEK 511
Query: 176 LERSEERAEVAESRARQLEEELRTMDQALKSLMASEEEYSTKEDKYEEEIKLLEE-KLKE 234
+ R EE+ E + R+ EE++ ++ ++ +EE +E+K E+ K+ EE K +E
Sbjct: 512 VWRQEEKIREQEEKIREQEEKMWRQEEKIRE----QEEMWREEEKMHEQEKIWEEEKRQE 567
Query: 235 AETRAEFAERSVAKLEKTIDDLEETLASAKEENVE 269
E + E + + E+ + EE + +E+ E
Sbjct: 568 QEDKMWRQEEKIREQEEKVWRQEEKIREQEEKRQE 602
Score = 77.8 bits (190), Expect = 1e-14
Identities = 57/272 (20%), Positives = 134/272 (49%), Gaps = 7/272 (2%)
Query: 12 KLDKENAIDRAEQAEADKKQAEDRCKQLEEEQQALQK---KLKGTEDEVEKYSESVKEAQ 68
K ++ + R E+ ++++ + +++ E+++ ++K K+ E+++ + E ++E +
Sbjct: 471 KRQEQEEMWRQEEKIHEQEEIWRQKEKMHEQEEKIRKQEEKVWRQEEKIREQEEKIREQE 530
Query: 69 EKLEQAEKKATDAEA---DVASLNRRIQLVEEELDRAQE-RLATALQKLEEAEKAADESE 124
EK+ + E+K + E + ++ + ++ EEE + QE ++ +K+ E E+ E
Sbjct: 531 EKMWRQEEKIREQEEMWREEEKMHEQEKIWEEEKRQEQEDKMWRQEEKIREQEEKVWRQE 590
Query: 125 RGMKVIENRAMKDEEKMELQEMQLKEAKHIAEDSDRKYEEVARKLVILEGELERSEERAE 184
++ E + + EEKM QE +++E + ++ + K E K+ E + EE+
Sbjct: 591 EKIREQEEKRQEQEEKMWKQEEKIREQEEKIQEQEEKIREQEEKIREQEEMTQEQEEKMG 650
Query: 185 VAESRARQLEEELRTMDQALKSLMASEEEYSTKEDKYEEEIKLLEEKLKEAETRAEFAER 244
E + + EE+++ ++ + E K + EE+I+ EE ++E E + E
Sbjct: 651 EQEEKMCEQEEKMQEQEETMWRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEE 710
Query: 245 SVAKLEKTIDDLEETLASAKEENVEIHQTLDQ 276
+ + E+ + + EE + +E+ E L Q
Sbjct: 711 KMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQ 742
Score = 77.4 bits (189), Expect = 1e-14
Identities = 67/250 (26%), Positives = 128/250 (51%), Gaps = 27/250 (10%)
Query: 37 KQLEEEQQALQKKLKGTEDEVEKYSESVKEAQEKLEQAE----KKATDAEAD-----VAS 87
++L+E+ LQ+KL+ E E + +VKE + KLE+A+ ++ AEAD + S
Sbjct: 217 EELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQS 276
Query: 88 LNRRIQLVEEELD-------RAQERLATALQKLEEAEKAADESERGMKVIENRAMKDEEK 140
++ ++Q EE + + +E++ +K++E E+ E E ++ E + + EEK
Sbjct: 277 VSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEK 336
Query: 141 MELQEMQLKEAKHIAEDSDRKYEEVARKLVILEGELERSEERAEVAESRARQLEEELRTM 200
M QE + E E+ R+ EE+ + E ++ R EE E + R+ EE +
Sbjct: 337 MRRQEEMMWE----KEEKMRRQEEMMWE---KEEKMRRQEEMMWEKEEKMRRQEEMMWEK 389
Query: 201 DQALKSL---MASEEEYSTKEDKYEEEIKLLE-EKLKEAETRAEFAERSVAKLEKTIDDL 256
++ ++ L M +E+ +E+K +EE K+ E EK +E E + E + + E+ I +
Sbjct: 390 EEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQ 449
Query: 257 EETLASAKEE 266
E+ + +E+
Sbjct: 450 EKKMWRQEEK 459
Score = 76.6 bits (187), Expect = 2e-14
Identities = 58/257 (22%), Positives = 130/257 (50%), Gaps = 13/257 (5%)
Query: 20 DRAEQAEADKKQAEDRCKQLEEEQQALQKKLKGTEDEVEKYSESVKEAQEKLEQAE---- 75
++ ++ EA + E++ ++ EE+ + +KK+ E+++ + E ++E +++ EQ E
Sbjct: 423 EKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIHE-QEKIREEEKRQEQEEMWRQ 481
Query: 76 KKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGM-----KVI 130
++ + ++ ++ EE++ + +E++ +K+ E E+ E E M K+
Sbjct: 482 EEKIHEQEEIWRQKEKMHEQEEKIRKQEEKVWRQEEKIREQEEKIREQEEKMWRQEEKIR 541
Query: 131 ENRAM-KDEEKMELQEMQLKEAKHIAEDSDRKYEEVARKLVILEGELERSEERAEVAESR 189
E M ++EEKM QE +E K E D+ + + K+ E ++ R EE+ E +
Sbjct: 542 EQEEMWREEEKMHEQEKIWEEEKR-QEQEDKMWRQ-EEKIREQEEKVWRQEEKIREQEEK 599
Query: 190 ARQLEEELRTMDQALKSLMASEEEYSTKEDKYEEEIKLLEEKLKEAETRAEFAERSVAKL 249
++ EE++ ++ ++ +E K + EE+I+ EE +E E + E + +
Sbjct: 600 RQEQEEKMWKQEEKIREQEEKIQEQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQ 659
Query: 250 EKTIDDLEETLASAKEE 266
E+ + + EET+ +E+
Sbjct: 660 EEKMQEQEETMWRQEEK 676
Score = 76.3 bits (186), Expect = 3e-14
Identities = 59/270 (21%), Positives = 134/270 (49%), Gaps = 15/270 (5%)
Query: 1 MDAIKKKMQMLKLDKENAIDRAEQAEADKK-QAEDRCKQLEEEQQALQKKLKGTEDEVEK 59
+ ++ K+Q ++++ +R Q + +K + E++ ++ EE+ Q ++K++ E
Sbjct: 274 LQSVSAKLQA-QVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQE----- 327
Query: 60 YSESVKEAQEKLEQAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKA 119
E ++E +EK+ + E+ + E + + EE++ R +E + +K+ E+
Sbjct: 328 --EKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEM 385
Query: 120 ADESERGMKVIENRAMKDEEKMELQEMQLKEAKHIAEDSDRKYEEVARKLVILEGELERS 179
E E ++ +E + M ++EK+ QE + +E + I E R+ +E K+ E ++
Sbjct: 386 MWEKEEKIRELEEK-MHEQEKIREQEEKRQEEEKIREQEKRQEQEA--KMWRQEEKIREQ 442
Query: 180 EERAEVAESRARQLEEELRTMDQALKSLMASEEEYSTKEDK---YEEEIKLLEEKLKEAE 236
EE+ E + + EE++ ++ + E+E ++++ +EEI +EK+ E E
Sbjct: 443 EEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIHEQEEIWRQKEKMHEQE 502
Query: 237 TRAEFAERSVAKLEKTIDDLEETLASAKEE 266
+ E V + E+ I + EE + +E+
Sbjct: 503 EKIRKQEEKVWRQEEKIREQEEKIREQEEK 532
Score = 71.6 bits (174), Expect = 7e-13
Identities = 60/251 (23%), Positives = 119/251 (47%), Gaps = 18/251 (7%)
Query: 1 MDAIKKKMQMLKLDKENAIDRAEQAEADKKQAEDRCKQLEEEQQALQKKLKGTEDEVEKY 60
+++ K ++Q+ + + ++RA+ ++Q + L +E Q++ KL+ +E E +
Sbjct: 233 VESEKSEIQLNVKELKRKLERAKLL-LPQQQLQAEADHLGKELQSVSAKLQAQVEENELW 291
Query: 61 SESVKEAQEKLEQAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAA 120
+ ++ +EK+ + E+K + E +IQ EE++ +E++ +K+ E+
Sbjct: 292 NRLNQQQEEKMWRQEEKIQEWE-------EKIQEQEEKIREQEEKIREQEEKMRRQEEMM 344
Query: 121 DESERGMKVIENRAMKDEEKMELQEMQLKEAKHIAEDSDRKYEEVARKLVILEGELERSE 180
E E M+ E + EEKM QE + E + + E K+ LE ++ E
Sbjct: 345 WEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQE 404
Query: 181 ERAEVAESRARQLEEELRTMDQALKSLMASEEEYSTKEDKYEEEIKLLEEKLKEAETRAE 240
+ E E RQ EE++R ++ +E K + EE+I+ EEK++E E +
Sbjct: 405 KIREQEEK--RQEEEKIREQEK--------RQEQEAKMWRQEEKIREQEEKIREQEKKMW 454
Query: 241 FAERSVAKLEK 251
E + + EK
Sbjct: 455 RQEEKIHEQEK 465
Score = 71.6 bits (174), Expect = 7e-13
Identities = 44/213 (20%), Positives = 105/213 (49%)
Query: 2 DAIKKKMQMLKLDKENAIDRAEQAEADKKQAEDRCKQLEEEQQALQKKLKGTEDEVEKYS 61
+ I+++ +M + +++ E +++ ED+ + EE+ + ++K+ E+++ +
Sbjct: 538 EKIREQEEMWREEEKMHEQEKIWEEEKRQEQEDKMWRQEEKIREQEEKVWRQEEKIREQE 597
Query: 62 ESVKEAQEKLEQAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAAD 121
E +E +EK+ + E+K + E + +I+ EE++ +E +K+ E E+
Sbjct: 598 EKRQEQEEKMWKQEEKIREQEEKIQEQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMC 657
Query: 122 ESERGMKVIENRAMKDEEKMELQEMQLKEAKHIAEDSDRKYEEVARKLVILEGELERSEE 181
E E M+ E + EEK+ QE +++E + + + +E K+ E ++ EE
Sbjct: 658 EQEEKMQEQEETMWRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEE 717
Query: 182 RAEVAESRARQLEEELRTMDQALKSLMASEEEY 214
+ + E + R+ EE++ + L+ +E+
Sbjct: 718 KMQEQEEKMRRQEEKMWEQEVRLRQQEEKMQEH 750
Score = 69.3 bits (168), Expect = 4e-12
Identities = 50/252 (19%), Positives = 121/252 (48%), Gaps = 21/252 (8%)
Query: 2 DAIKKKMQMLKLDKENAIDRAEQAEADKKQAEDRCKQLEEEQQALQKKLKGTEDEVEKYS 61
+ + ++ + ++ +E ++ E+ +++ ++ + EE++ +++ E++ ++
Sbjct: 510 EKVWRQEEKIREQEEKIREQEEKMWRQEEKIREQEEMWREEEKMHEQEKIWEEEKRQEQE 569
Query: 62 ESVKEAQEKLEQAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAAD 121
+ + +EK+ + E+K E + + Q EE++ + +E++ +K++E E+
Sbjct: 570 DKMWRQEEKIREQEEKVWRQEEKIREQEEKRQEQEEKMWKQEEKIREQEEKIQEQEEKIR 629
Query: 122 ESERGMKVIENRAMKDEEKMELQEMQLKEAKHIAEDSDRKYEEVARKLVILEGELERSEE 181
E E ++ E + EEKM QE + + E ++ E+ E + R EE
Sbjct: 630 EQEEKIREQEEMTQEQEEKMGEQE------EKMCEQEEKMQEQ--------EETMWRQEE 675
Query: 182 RAEVAESRARQLEEELRTMDQAL----KSLMASEEEYSTKEDK---YEEEIKLLEEKLKE 234
+ E + R+ EE++R ++ + + + EE+ +E+K EE+++ EEK+ E
Sbjct: 676 KIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWE 735
Query: 235 AETRAEFAERSV 246
E R E +
Sbjct: 736 QEVRLRQQEEKM 747
Score = 61.6 bits (148), Expect = 7e-10
Identities = 63/270 (23%), Positives = 124/270 (45%), Gaps = 22/270 (8%)
Query: 5 KKKMQMLKLDKENAIDRAEQAEADK-KQAEDRCKQLEEEQQALQKKLKGTEDEVEKYSES 63
K ++QM ++A+ + E D + D K E +QAL + + + ++Y E
Sbjct: 139 KTELQMALYYSQHAVKQLEGEARDLISRLHDSWKFAGELEQALSA-VATQKKKADRYIEE 197
Query: 64 VKEAQE--KLEQAEKKATDAEADV--ASLNRRIQLVEEELDRAQERLATALQKLEEAEKA 119
+ + ++ LE TD E A L ++QLVE E Q + +KLE A+
Sbjct: 198 LTKERDALSLELYRNTITDEELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLERAKLL 257
Query: 120 ADESERGMKVIENRAMKDEEKMELQEMQLKEAKHIAEDS--DRKYEEVARKLVILEGELE 177
+ + +A D ELQ + K + E+ +R ++ K+ E +++
Sbjct: 258 LPQQQL-------QAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQ 310
Query: 178 RSEERAEVAESRARQLEEELRTMDQALK---SLMASEEEYSTKEDKY----EEEIKLLEE 230
EE+ + E + R+ EE++R ++ ++ +M +EE ++++ EE+++ EE
Sbjct: 311 EWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEE 370
Query: 231 KLKEAETRAEFAERSVAKLEKTIDDLEETL 260
+ E E + E + + E+ I +LEE +
Sbjct: 371 MMWEKEEKMRRQEEMMWEKEEKIRELEEKM 400
Score = 53.9 bits (128), Expect = 2e-07
Identities = 56/247 (22%), Positives = 111/247 (44%), Gaps = 26/247 (10%)
Query: 33 EDRCKQLEEEQQALQKKLKGTEDEVEKYSESVKEAQEKLEQAEKKATDAEADVASLNRRI 92
ED K + Q+AL+++L+ + + E Q L ++ E + L R+
Sbjct: 108 EDEQKASHQHQEALRRELEAQVHTIRILTCQKTELQMALYYSQHAVKQLEGEARDLISRL 167
Query: 93 Q---LVEEELDRAQERLATALQK----LEEAEKAAD--ESERGMKVIENRAMKD-----E 138
EL++A +AT +K +EE K D E I + +K+ +
Sbjct: 168 HDSWKFAGELEQALSAVATQKKKADRYIEELTKERDALSLELYRNTITDEELKEKNAKLQ 227
Query: 139 EKMELQEMQLKEAKHIAEDSDRKYEEVARKLVILEGELERSEERAEVAESRARQLEEELR 198
EK++L E + E + ++ RK E KL++ + +L ++ A L +EL+
Sbjct: 228 EKLQLVESEKSEIQLNVKELKRKLERA--KLLLPQQQL----------QAEADHLGKELQ 275
Query: 199 TMDQALKSLMASEEEYSTKEDKYEEEIKLLEEKLKEAETRAEFAERSVAKLEKTIDDLEE 258
++ L++ + E ++ + EE++ EEK++E E + + E + + E+ I + EE
Sbjct: 276 SVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEE 335
Query: 259 TLASAKE 265
+ +E
Sbjct: 336 KMRRQEE 342
>gi|239745299 PREDICTED: hypothetical protein [Homo sapiens]
Length = 523
Score = 84.7 bits (208), Expect = 8e-17
Identities = 71/266 (26%), Positives = 127/266 (47%), Gaps = 23/266 (8%)
Query: 9 QMLKLDKENAIDRAEQAEADKKQAEDRCKQLEEEQQALQKKLKGTEDEVEKYSESVKEAQ 68
QML L +R + E ++ E+R ++ EE +++L+ E+ + + E + E +
Sbjct: 188 QMLSLLNRRQEERLREQEERLREQEERLREQEERLCEQEERLREQEERLREQEERLCEQE 247
Query: 69 EKLEQAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMK 128
E+L + E++ + E + R++ EE L +ERL ++L E E+ E E ++
Sbjct: 248 ERLREHEERLCEQEERLCEQEERLREQEERLHEQEERLCEQEERLREQEERLCEQEERLR 307
Query: 129 VIENRAMKDEEKMELQEMQLKEAKHIAEDSDRKYEEVARKLVILEGELERSEERAEVAES 188
E R + EE++ QE +L E + + +R EEV + L E ER +E E
Sbjct: 308 EQEERLCEQEERLREQEERLCEQEKL-PGQERLLEEVEKLL-----EQERRQEEQERLLE 361
Query: 189 RARQLEEELRTMDQALKSLMASEEEYSTKEDKYE-EEIKLLEEKL---------KEAETR 238
R R LEE ++Q + L +E +E E E ++ LE L + AE R
Sbjct: 362 RERLLEEVEELLEQ--ERLRQQDERLWQQETLQELERLRELERMLELGWEALYEQRAEPR 419
Query: 239 AEFAE-----RSVAKLEKTIDDLEET 259
+ F E +S +LE+ + +L+++
Sbjct: 420 SGFEELNNENKSTLQLEQQVKELKKS 445
Score = 83.2 bits (204), Expect = 2e-16
Identities = 73/277 (26%), Positives = 128/277 (46%), Gaps = 18/277 (6%)
Query: 10 MLKLDKENAIDRAEQAEADKKQAEDRCKQLEEEQQALQKKLKGTEDEVEKYSESVKEAQE 69
+ KL + A A + A + E QL++E L+K+L+ +++ E+ +
Sbjct: 137 LFKLKNQTAEPLAPEPPAGPSKVE----QLQDETNHLRKELESVGRQLQAEVENNQMLSL 192
Query: 70 KLEQAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKV 129
+ E++ + E + R++ EE L +ERL ++L E E+ E E ++
Sbjct: 193 LNRRQEERLREQEERLREQEERLREQEERLCEQEERLREQEERLREQEERLCEQEERLRE 252
Query: 130 IENRAMKDEEKMELQEMQLKEAKHIAEDSDRKYEEVARKLVILEGELERSEERAEVAESR 189
E R + EE++ QE +L+E + + E +L E L EER E R
Sbjct: 253 HEERLCEQEERLCEQEERLRE-------QEERLHEQEERLCEQEERLREQEERLCEQEER 305
Query: 190 ARQLEEELRTMDQALKSLMASEEEYSTKEDKYEEEIKLLE--EKLKEAETRAEFAERSVA 247
R+ EE L ++ L+ +EE +++K + +LLE EKL E E R E ER +
Sbjct: 306 LREQEERLCEQEERLR----EQEERLCEQEKLPGQERLLEEVEKLLEQERRQEEQERLLE 361
Query: 248 KLEKTIDDLEETLASAKEENVEIHQTLDQTLLELNNL 284
+ E+ ++++EE L + + +TL EL L
Sbjct: 362 R-ERLLEEVEELLEQERLRQQDERLWQQETLQELERL 397
Score = 75.1 bits (183), Expect = 7e-14
Identities = 67/281 (23%), Positives = 134/281 (47%), Gaps = 10/281 (3%)
Query: 4 IKKKMQMLKLDKENAIDRAEQAEADKKQAEDRCKQLEEEQQALQKKLKGTEDEVEKYSES 63
++K+++ + + ++ + ++ E+R ++ EE + +++L+ E+ + + E
Sbjct: 169 LRKELESVGRQLQAEVENNQMLSLLNRRQEERLREQEERLREQEERLREQEERLCEQEER 228
Query: 64 VKEAQEKLEQAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADES 123
++E +E+L + E++ + E + R+ EE L +ERL ++L E E+ E
Sbjct: 229 LREQEERLREQEERLCEQEERLREHEERLCEQEERLCEQEERLREQEERLHEQEERLCEQ 288
Query: 124 ERGMKVIENRAMKDEEKMELQEMQLKEAKHIAEDSDRKYEEVARKLVILEGELERSEERA 183
E ++ E R + EE++ QE +L E E+ R+ EE + L G+ EE
Sbjct: 289 EERLREQEERLCEQEERLREQEERLCE----QEERLREQEERLCEQEKLPGQERLLEEVE 344
Query: 184 EVAESRARQLEEELRTMDQALKSLMASEEEYSTKEDKYEEEIKL-LEEKLKEAETRAEFA 242
++ E RQ EE+ R +++ + L+ EE +E +++ +L +E L+E E E
Sbjct: 345 KLLEQERRQ-EEQERLLER--ERLLEEVEELLEQERLRQQDERLWQQETLQELERLRELE 401
Query: 243 ERSVAKLEKTIDDLEETLASAKEENVEIHQT--LDQTLLEL 281
E + E + +E N E T L+Q + EL
Sbjct: 402 RMLELGWEALYEQRAEPRSGFEELNNENKSTLQLEQQVKEL 442
>gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo
sapiens]
Length = 668
Score = 84.3 bits (207), Expect = 1e-16
Identities = 65/278 (23%), Positives = 136/278 (48%), Gaps = 15/278 (5%)
Query: 2 DAIKKKMQMLKLDKENAIDRAEQAEADKKQAEDRCKQLEEEQQALQKKLKGTEDEVEKYS 61
D + K++Q + + ++ E +Q E++ + EE+ Q ++K++ E+++ +
Sbjct: 268 DHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQE 327
Query: 62 ESVKEAQEKLEQAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAAD 121
E ++E +EK+ + E+ + E + + EE++ R +E + +K+ E E+
Sbjct: 328 EKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRLEEMMWEKEEKIRELEEKMH 387
Query: 122 ESERGMKVIENR----AMKDEEKMELQEMQLKEAKHIAEDSDRKYEEVARKL-----VIL 172
E E+ + E R ++++EK + QE ++ + + + K E +K+ I
Sbjct: 388 EQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIH 447
Query: 173 EGELERSEERAEVAESRARQLEEELRTMDQ--ALKSLMASEEEYSTKEDK---YEEEIKL 227
E E R EE+ + E RQ EE++R ++ K M +E+ +E+K EE++
Sbjct: 448 EQEKIREEEKRQEQEEMWRQ-EEKIREQEEIWRQKEKMHEQEKIRKQEEKVWRQEEKMHD 506
Query: 228 LEEKLKEAETRAEFAERSVAKLEKTIDDLEETLASAKE 265
EEK++E E + E + + E+ I + EE + +E
Sbjct: 507 QEEKIREQEEKMWRQEEKIREQEEKIREQEEKIREQEE 544
Score = 82.8 bits (203), Expect = 3e-16
Identities = 66/289 (22%), Positives = 137/289 (47%), Gaps = 20/289 (6%)
Query: 6 KKMQMLKLDKENAIDRAEQA---------EADKKQAEDRCKQLEEEQQALQKKLKGTEDE 56
++++ + +KE I E+ + +K+Q E++ ++ +E++Q + K+ E++
Sbjct: 366 RRLEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIRE-QEKRQEQEAKMWRQEEK 424
Query: 57 VEKYSESVKEAQEKLEQAEKKATDAEADVASLNRRIQLV---EEELDRAQERLATALQKL 113
+ + E ++E ++K+ + E+K + E R+ Q +EE R QE + +K+
Sbjct: 425 IREQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKM 484
Query: 114 EEAEKAADESER------GMKVIENRAMKDEEKMELQEMQLKEAKHIAEDSDRKYEEVAR 167
E EK + E+ M E + + EEKM QE +++E + + + K E
Sbjct: 485 HEQEKIRKQEEKVWRQEEKMHDQEEKIREQEEKMWRQEEKIREQEEKIREQEEKIREQEE 544
Query: 168 KLVILEGELERSEERAEVAESRARQLEEELRTMDQALKSLMASEEEYSTKEDKYEEEIKL 227
+ E ++ EE+ + E RQ EE++R ++ ++ E K + EE+I+
Sbjct: 545 MMQEQEEKMGEQEEKMQEQEKMRRQ-EEKIREQEEKIREQKEKIREQEEKIWEQEEKIRE 603
Query: 228 LEEKLKEAETRAEFAERSVAKLEKTIDDLEETLASAKEENVEIHQTLDQ 276
EE ++E E + E + + E+ + + EE + +E+ E L Q
Sbjct: 604 QEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQ 652
Score = 80.1 bits (196), Expect = 2e-15
Identities = 59/248 (23%), Positives = 128/248 (51%), Gaps = 10/248 (4%)
Query: 2 DAIKKKMQMLKLDKENAIDRAEQAEADKKQAEDRCKQLEEEQQALQKKLKGTEDEVEKYS 61
+ I+++ + ++ ++ + E+ +K E+ +Q +EE ++K++ ++E+ +
Sbjct: 423 EKIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIR-EQEEIWRQK 481
Query: 62 ESVKEAQEKLEQAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAAD 121
E + E QEK+ + E+K E + +I+ EE++ R +E++ +K+ E E+
Sbjct: 482 EKMHE-QEKIRKQEEKVWRQEEKMHDQEEKIREQEEKMWRQEEKIREQEEKIREQEEKIR 540
Query: 122 ESERGMKVIENRAMKDEEKMELQEMQLKEAKHIAEDSDRKYEEVARKLVILEGELERSEE 181
E E M+ E + + EEKM+ QE ++ + I E + K E K+ E ++ EE
Sbjct: 541 EQEEMMQEQEEKMGEQEEKMQEQEKMRRQEEKIREQEE-KIREQKEKIREQEEKIWEQEE 599
Query: 182 RAEVAESRARQLEEELRTMDQAL----KSLMASEEEYSTKEDK-YEEEIKL--LEEKLKE 234
+ E ++ EE++ ++ + + + EE+ +E+K +E+E++L EEK++E
Sbjct: 600 KIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQEEKMQE 659
Query: 235 AETRAEFA 242
+ E A
Sbjct: 660 HQEHLEAA 667
Score = 79.0 bits (193), Expect = 5e-15
Identities = 67/253 (26%), Positives = 127/253 (50%), Gaps = 27/253 (10%)
Query: 37 KQLEEEQQALQKKLKGTEDEVEKYSESVKEAQEKLEQAE----KKATDAEAD-----VAS 87
++L+E+ LQ+KL+ E E + +VKE + KLE+A+ ++ AEAD + S
Sbjct: 217 EELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQS 276
Query: 88 LNRRIQLVEEELD-------RAQERLATALQKLEEAEKAADESERGMKVIENRAMKDEEK 140
++ ++Q EE + + +E++ +K++E E+ E E ++ E + + EEK
Sbjct: 277 VSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEK 336
Query: 141 MELQEMQLKEAKHIAEDSDRKYEEVARKLVILEGELERSEERAEVAESRARQLEEELRTM 200
M QE + E E+ R+ EE+ + E ++ R EE E + R+LEE++
Sbjct: 337 MRRQEEMMWE----KEEKMRRQEEMMWE---KEEKMRRLEEMMWEKEEKIRELEEKMHEQ 389
Query: 201 D--QALKSLMASEEEYSTKEDKYEEEIKL--LEEKLKEAETRAEFAERSVAKLEKTIDDL 256
+ + + EE+ +E + E+E K+ EEK++E E + E+ + + E+ I +
Sbjct: 390 EKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQ 449
Query: 257 EETLASAKEENVE 269
E+ K + E
Sbjct: 450 EKIREEEKRQEQE 462
Score = 77.4 bits (189), Expect = 1e-14
Identities = 62/268 (23%), Positives = 139/268 (51%), Gaps = 26/268 (9%)
Query: 6 KKMQMLKLDKENAIDRAEQAEADKKQAEDRCKQLEEEQQALQKKLKGTEDEVEKYSESVK 65
++ + + +KE + R E+ +K E++ ++LEE ++K++ E+++ + E ++
Sbjct: 338 RRQEEMMWEKEEKMRRQEEMMWEK---EEKMRRLEEMMWEKEEKIRELEEKMHE-QEKIR 393
Query: 66 EAQEKLEQAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESER 125
E +EK ++ EK + +R Q E ++ R +E++ +K+ E EK E
Sbjct: 394 EQEEKRQEEEK--------IREQEKR-QEQEAKMWRQEEKIREQEEKIREQEKKMWRQEE 444
Query: 126 GM----KVIENRAMKDEEKMELQEMQLKEAKHIAEDSDRKYEEVARKLVILEGELERSEE 181
+ K+ E +++E+M QE +++E + I ++ +E+ K+ E ++ R EE
Sbjct: 445 KIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKMHEQ--EKIRKQEEKVWRQEE 502
Query: 182 RAEVAESRARQLEEELRTMDQALKSLMASEEEYSTKEDKYEEEIKLL---EEKLKEAETR 238
+ E + R+ EE++ ++ ++ EE+ +E+K E+ +++ EEK+ E E +
Sbjct: 503 KMHDQEEKIREQEEKMWRQEEKIRE---QEEKIREQEEKIREQEEMMQEQEEKMGEQEEK 559
Query: 239 AEFAERSVAKLEKTIDDLEETLASAKEE 266
+ E+ + + E+ I + EE + KE+
Sbjct: 560 MQEQEK-MRRQEEKIREQEEKIREQKEK 586
Score = 76.6 bits (187), Expect = 2e-14
Identities = 66/269 (24%), Positives = 131/269 (48%), Gaps = 21/269 (7%)
Query: 19 IDRAEQAEADKKQAEDR-CKQLEEEQQALQKKLKGTEDEVEKYSESVKEAQEKLEQAEKK 77
+++A A A +K+ DR ++L +E+ AL +L E+ E + QEKL+ E +
Sbjct: 177 LEQALSAVATQKKKADRYIEELTKERDALSLELYRNTITDEELKEKNAKLQEKLQLVESE 236
Query: 78 ATDAEADVASLNRRIQ-----LVEEELDRAQERLATALQ--------KLEEAE---KAAD 121
++ + +V L R+++ L +++L + L LQ ++EE E +
Sbjct: 237 KSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEENELWNRLNQ 296
Query: 122 ESERGMKVIENRAMKDEEKMELQEMQLKEAKHIAEDSDRKYEEVARKLVILEGELERSEE 181
+ E M E + + EEK++ QE +++E + + + K + E ++ R EE
Sbjct: 297 QQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEE 356
Query: 182 RAEVAESRARQLEEELRTMDQALKSL---MASEEEYSTKEDKYEEEIKLLE-EKLKEAET 237
E + R+LEE + ++ ++ L M +E+ +E+K +EE K+ E EK +E E
Sbjct: 357 MMWEKEEKMRRLEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEA 416
Query: 238 RAEFAERSVAKLEKTIDDLEETLASAKEE 266
+ E + + E+ I + E+ + +E+
Sbjct: 417 KMWRQEEKIREQEEKIREQEKKMWRQEEK 445
Score = 76.6 bits (187), Expect = 2e-14
Identities = 56/256 (21%), Positives = 131/256 (51%), Gaps = 12/256 (4%)
Query: 20 DRAEQAEADKKQAEDRCKQLEEEQQALQKKLKGTEDEVEKYSESVKEAQEKLEQAE---K 76
++ ++ EA + E++ ++ EE+ + +KK+ E+++ + E ++E +++ EQ E +
Sbjct: 409 EKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIHE-QEKIREEEKRQEQEEMWRQ 467
Query: 77 KATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIENRAMK 136
+ E + + +E++ + +E++ +K+ + E+ E E M E + +
Sbjct: 468 EEKIREQEEIWRQKEKMHEQEKIRKQEEKVWRQEEKMHDQEEKIREQEEKMWRQEEKIRE 527
Query: 137 DEEKMELQEMQLKEAKHIAEDSDRKYEEVARKLVILEGELERSEERAEVAESRARQLEEE 196
EEK+ QE +++E + + ++ + K E K+ E ++ R EE+ E + R+ +E+
Sbjct: 528 QEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMQEQE-KMRRQEEKIREQEEKIREQKEK 586
Query: 197 LRTMDQAL----KSLMASEEEYSTKEDK-YEEEIKLLE--EKLKEAETRAEFAERSVAKL 249
+R ++ + + + EE +E+K +E+E K+ E EK++E E + E + +
Sbjct: 587 IREQEEKIWEQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQ 646
Query: 250 EKTIDDLEETLASAKE 265
E + EE + +E
Sbjct: 647 EVRLRQQEEKMQEHQE 662
Score = 73.9 bits (180), Expect = 1e-13
Identities = 62/293 (21%), Positives = 135/293 (46%), Gaps = 47/293 (16%)
Query: 20 DRAEQAEADKKQAEDRCKQLEEEQQALQKKLKGTEDEVEKYSESVKEAQEKLEQAEKKAT 79
++ ++ E ++ E++ ++ EE+ + ++ + E+++ + E + E +EK+ + E+
Sbjct: 314 EKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRLEEMMW 373
Query: 80 DAEADVASLNRRI-----------QLVEEELDRAQE-------RLATALQKLEEAEKAAD 121
+ E + L ++ + EEE R QE ++ +K+ E E+
Sbjct: 374 EKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIR 433
Query: 122 ESERGM-----KVIENRAMKDEEKMELQEMQLKEAKHIAEDSD--------------RKY 162
E E+ M K+ E +++EEK + QE ++ + I E + RK
Sbjct: 434 EQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKMHEQEKIRKQ 493
Query: 163 EEVA----RKLVILEGELERSEERAEVAESRARQLEEELRTMDQALKS----LMASEEEY 214
EE K+ E ++ EE+ E + R+ EE++R ++ ++ + EE+
Sbjct: 494 EEKVWRQEEKMHDQEEKIREQEEKMWRQEEKIREQEEKIREQEEKIREQEEMMQEQEEKM 553
Query: 215 STKEDKYEEEIKL--LEEKLKEAETRAEFAERSVAKLEKTIDDLEETLASAKE 265
+E+K +E+ K+ EEK++E E + + + + E+ I + EE + +E
Sbjct: 554 GEQEEKMQEQEKMRRQEEKIREQEEKIREQKEKIREQEEKIWEQEEKIREQEE 606
Score = 65.1 bits (157), Expect = 7e-11
Identities = 57/261 (21%), Positives = 126/261 (48%), Gaps = 20/261 (7%)
Query: 1 MDAIKKKMQMLKLDKENAIDRAEQAEADKKQAEDRCKQLEEEQQALQKKLKGTEDEVEKY 60
+++ K ++Q+ + + ++RA+ ++Q + L +E Q++ KL+ +E E +
Sbjct: 233 VESEKSEIQLNVKELKRKLERAKLL-LPQQQLQAEADHLGKELQSVSAKLQAQVEENELW 291
Query: 61 SESVKEAQEKLEQAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAA 120
+ ++ +EK+ + E+K IQ EE++ +E++ +K+ E E+
Sbjct: 292 NRLNQQQEEKMWRQEEK--------------IQEWEEKIQEQEEKIREQEEKIREQEEKM 337
Query: 121 DESERGMKVIENRAMKDEEKMELQEMQLKEAKHIAEDSDRKYEEVARKLVILEGELERSE 180
E M E + + EE M +E +++ + + + + K E+ K+ E E+ E
Sbjct: 338 RRQEEMMWEKEEKMRRQEEMMWEKEEKMRRLEEMMWEKEEKIRELEEKMHEQEKIREQEE 397
Query: 181 ERAEVAESRARQLEEELRTMDQALKSLMASEEEYSTKEDK--YEEEIKLLE-EKLKEAET 237
+R E + R ++ +E + + +EE +++K + +E K+ E EK++E E
Sbjct: 398 KRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIREEEK 457
Query: 238 RAEFAERSVAKLEKTIDDLEE 258
R E + + + E+ I + EE
Sbjct: 458 RQE--QEEMWRQEEKIREQEE 476
Score = 53.9 bits (128), Expect = 2e-07
Identities = 56/247 (22%), Positives = 111/247 (44%), Gaps = 26/247 (10%)
Query: 33 EDRCKQLEEEQQALQKKLKGTEDEVEKYSESVKEAQEKLEQAEKKATDAEADVASLNRRI 92
ED K + Q+AL+++L+ + + E Q L ++ E + L R+
Sbjct: 108 EDEQKASHQHQEALRRELEAQVHTIRILTCQKTELQMALYYSQHAVKQLEGEARDLISRL 167
Query: 93 Q---LVEEELDRAQERLATALQK----LEEAEKAAD--ESERGMKVIENRAMKD-----E 138
EL++A +AT +K +EE K D E I + +K+ +
Sbjct: 168 HDSWKFAGELEQALSAVATQKKKADRYIEELTKERDALSLELYRNTITDEELKEKNAKLQ 227
Query: 139 EKMELQEMQLKEAKHIAEDSDRKYEEVARKLVILEGELERSEERAEVAESRARQLEEELR 198
EK++L E + E + ++ RK E KL++ + +L ++ A L +EL+
Sbjct: 228 EKLQLVESEKSEIQLNVKELKRKLERA--KLLLPQQQL----------QAEADHLGKELQ 275
Query: 199 TMDQALKSLMASEEEYSTKEDKYEEEIKLLEEKLKEAETRAEFAERSVAKLEKTIDDLEE 258
++ L++ + E ++ + EE++ EEK++E E + + E + + E+ I + EE
Sbjct: 276 SVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEE 335
Query: 259 TLASAKE 265
+ +E
Sbjct: 336 KMRRQEE 342
Score = 53.9 bits (128), Expect = 2e-07
Identities = 62/252 (24%), Positives = 124/252 (49%), Gaps = 29/252 (11%)
Query: 37 KQLEEEQQALQKKLKGT---EDEVEKYSESVKEAQEKLEQAEKKATDAEADVASLNR-RI 92
KQLE E + L +L + E+E+ +V ++K ++ ++ T E D SL R
Sbjct: 154 KQLEGEARDLISRLHDSWKFAGELEQALSAVATQKKKADRYIEELTK-ERDALSLELYRN 212
Query: 93 QLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIENRAMKDEEKMELQEMQLK-EA 151
+ +EEL +L LQ +E +++SE + V E + + K+ L + QL+ EA
Sbjct: 213 TITDEELKEKNAKLQEKLQLVE-----SEKSEIQLNVKELKRKLERAKLLLPQQQLQAEA 267
Query: 152 KHIAEDSDRKYEEVARKLV--ILEGEL-----ERSEERAEVAESRARQLEEELRTMDQAL 204
H+ ++ + V+ KL + E EL ++ EE+ E + ++ EE+++ ++ +
Sbjct: 268 DHLGKE----LQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKI 323
Query: 205 KSLMASEEEYSTKEDKYEEEIKLLEEKLKEAETRAEFAERSVAKLEKTIDDLEETLASAK 264
+ E+E +E EE+++ EE + E E + E + + E+ + LEE + +
Sbjct: 324 R-----EQEEKIREQ--EEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRLEEMMWEKE 376
Query: 265 EENVEIHQTLDQ 276
E+ E+ + + +
Sbjct: 377 EKIRELEEKMHE 388
Score = 38.1 bits (87), Expect = 0.009
Identities = 20/108 (18%), Positives = 59/108 (54%), Gaps = 3/108 (2%)
Query: 6 KKMQMLKLDKENAIDRAEQAEADKKQAEDRCKQLEEEQQALQKKLKGTEDEVEKY---SE 62
++ + ++ +E ++ E+ K++ ++ +++ E+++ ++++ + +++ EK E
Sbjct: 561 QEQEKMRRQEEKIREQEEKIREQKEKIREQEEKIWEQEEKIREQEEMMQEQEEKMWEQEE 620
Query: 63 SVKEAQEKLEQAEKKATDAEADVASLNRRIQLVEEELDRAQERLATAL 110
+ E +EK+++ E+K E + R++ EE++ QE L A+
Sbjct: 621 KMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQEEKMQEHQEHLEAAI 668
>gi|239745079 PREDICTED: Putative golgin subfamily A member 6-like
protein 6 [Homo sapiens]
Length = 724
Score = 84.3 bits (207), Expect = 1e-16
Identities = 62/275 (22%), Positives = 131/275 (47%), Gaps = 11/275 (4%)
Query: 2 DAIKKKMQMLKLDKENAIDRAEQAEADKKQAEDRCKQLEEEQQALQKKLKGTEDEVEKYS 61
+ ++++ +M+ +E + E+ +K E K+ EEE+ Q+K + E ++ +
Sbjct: 424 EKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQE 483
Query: 62 ESVKEAQEKLEQAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAAD 121
E ++E +EK+ + E+K E ++ + ++ EEE + QE + +K+ E E+
Sbjct: 484 EKIREQEEKIREQEEKMWRQE---EKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWR 540
Query: 122 ESERGMKVIENRAMKDEEKMELQEMQLKEAKHIAEDSDRKYEEVARKLVILEGELERSEE 181
+ E+ + E + K EEKM QE ++ D + K E K+ E ++ EE
Sbjct: 541 QKEK-IHEQEEKIRKQEEKMWRQEEKM-------HDQEEKIREQEEKVWRQEEKIREQEE 592
Query: 182 RAEVAESRARQLEEELRTMDQALKSLMASEEEYSTKEDKYEEEIKLLEEKLKEAETRAEF 241
+ E + R+ EE + ++ + E K + EE+++ EEK++E E +
Sbjct: 593 KIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEEKMRRQEEKIREQEKKIRE 652
Query: 242 AERSVAKLEKTIDDLEETLASAKEENVEIHQTLDQ 276
E + + E+ + + EE + +E+ E + + +
Sbjct: 653 QEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQE 687
Score = 84.0 bits (206), Expect = 1e-16
Identities = 52/250 (20%), Positives = 128/250 (51%), Gaps = 5/250 (2%)
Query: 20 DRAEQAEADKKQAEDRCKQLEEEQQALQKKLKGTEDEVEKYS----ESVKEAQEKLEQAE 75
++ ++ EA + E++ ++ EE+ + ++K+ E+++ + E ++ QE++ + E
Sbjct: 470 EKRQEQEAKMWRQEEKIREQEEKIREQEEKMWRQEEKIHEQEKIREEEKRQEQEEMWRQE 529
Query: 76 KKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIENRAM 135
+K + E ++ +I EE++ + +E++ +K+ + E+ E E + E +
Sbjct: 530 EKIREQE-EIWRQKEKIHEQEEKIRKQEEKMWRQEEKMHDQEEKIREQEEKVWRQEEKIR 588
Query: 136 KDEEKMELQEMQLKEAKHIAEDSDRKYEEVARKLVILEGELERSEERAEVAESRARQLEE 195
+ EEK+ QE +++E + + ++ + K E K+ E +++ EE+ E + R+ E+
Sbjct: 589 EQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEEKMRRQEEKIREQEK 648
Query: 196 ELRTMDQALKSLMASEEEYSTKEDKYEEEIKLLEEKLKEAETRAEFAERSVAKLEKTIDD 255
++R ++ ++ +E K + EE++ EEK++E E + E + + E +
Sbjct: 649 KIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQ 708
Query: 256 LEETLASAKE 265
EE + +E
Sbjct: 709 QEEKMQEHQE 718
Score = 83.6 bits (205), Expect = 2e-16
Identities = 65/290 (22%), Positives = 139/290 (47%), Gaps = 16/290 (5%)
Query: 2 DAIKKKMQMLKLDKENAIDRAEQAEADKKQAEDRCKQLEEEQQALQKKLKGTEDEVEKYS 61
D + K++Q + + ++ E +Q E++ + EE+ Q ++K++ E+++ +
Sbjct: 329 DHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQE 388
Query: 62 ESVKEAQEKLEQAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAAD 121
E ++E +EK+ + E+ + E + + EE++ R +E + +K+ E E+
Sbjct: 389 EKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMH 448
Query: 122 ESERGMKVIENR----AMKDEEKMELQEMQLKEAKHIAEDSDRKYEEVARKL-----VIL 172
E E+ + E R ++++EK + QE ++ + + + K E K+ I
Sbjct: 449 EQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEEKMWRQEEKIH 508
Query: 173 EGELERSEERAEVAESRARQLEEELRTMDQALK---SLMASEEEYSTKEDK---YEEEIK 226
E E R EE+ + E RQ EE++R ++ + + EE+ +E+K EE++
Sbjct: 509 EQEKIREEEKRQEQEEMWRQ-EEKIREQEEIWRQKEKIHEQEEKIRKQEEKMWRQEEKMH 567
Query: 227 LLEEKLKEAETRAEFAERSVAKLEKTIDDLEETLASAKEENVEIHQTLDQ 276
EEK++E E + E + + E+ I + EE + +E E + + +
Sbjct: 568 DQEEKIREQEEKVWRQEEKIREQEEKIREQEEKIREQEEMTQEQEEKMGE 617
Score = 83.2 bits (204), Expect = 2e-16
Identities = 52/249 (20%), Positives = 123/249 (49%), Gaps = 17/249 (6%)
Query: 2 DAIKKKMQMLKLDKENAIDRAEQAEADKKQAEDRCKQLEEEQQALQKKLKGTED------ 55
+ I+++ + ++ +E + E+ +K E+ +Q +EE ++K++ E+
Sbjct: 484 EKIREQEEKIREQEEKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKE 543
Query: 56 EVEKYSESVKEAQEKLEQAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEE 115
++ + E +++ +EK+ + E+K D E + ++ EE++ +E++ +K+ E
Sbjct: 544 KIHEQEEKIRKQEEKMWRQEEKMHDQEEKIREQEEKVWRQEEKIREQEEKIREQEEKIRE 603
Query: 116 AEKAADESERGMKVIENRAMKDEEKMELQEMQLKEAKHIAEDSDRKYEEVARKLVILEGE 175
E+ E E M E + + EEKM+ QE +++ + + ++K E K+ E
Sbjct: 604 QEEMTQEQEEKMGEQEEKMCEQEEKMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEM 663
Query: 176 LERSEERAEVAESRARQLEEELRTMDQALKSLMASEEEYSTKEDKYEEEIKL--LEEKLK 233
++ EE+ E + + EE+++ ++ ++ +E +E+E++L EEK++
Sbjct: 664 MQEQEEKMWEQEEKMCEQEEKMQEQEEKMR---------RQEEKMWEQEVRLRQQEEKMQ 714
Query: 234 EAETRAEFA 242
E + E A
Sbjct: 715 EHQEHLEAA 723
Score = 79.0 bits (193), Expect = 5e-15
Identities = 67/253 (26%), Positives = 126/253 (49%), Gaps = 27/253 (10%)
Query: 37 KQLEEEQQALQKKLKGTEDEVEKYSESVKEAQEKLEQAE----KKATDAEAD-----VAS 87
++L+E+ LQ+KL+ E E + +VKE + KLE+A+ ++ AEAD + S
Sbjct: 278 EELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQS 337
Query: 88 LNRRIQLVEEELD-------RAQERLATALQKLEEAEKAADESERGMKVIENRAMKDEEK 140
++ ++Q EE + + +E++ +K++E E+ E E ++ E + + EEK
Sbjct: 338 VSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEK 397
Query: 141 MELQEMQLKEAKHIAEDSDRKYEEVARKLVILEGELERSEERAEVAESRARQLEEELRTM 200
M QE + E E+ R+ EE+ + E ++ R EE E + R+LEE++
Sbjct: 398 MRRQEEMMWE----KEEKMRRQEEMMWE---KEEKMRRQEEMMWEKEEKIRELEEKMHEQ 450
Query: 201 D--QALKSLMASEEEYSTKEDKYEEEIKL--LEEKLKEAETRAEFAERSVAKLEKTIDDL 256
+ + + EE+ +E + E+E K+ EEK++E E + E + + E+ I +
Sbjct: 451 EKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEEKMWRQEEKIHEQ 510
Query: 257 EETLASAKEENVE 269
E+ K + E
Sbjct: 511 EKIREEEKRQEQE 523
Score = 77.0 bits (188), Expect = 2e-14
Identities = 61/290 (21%), Positives = 128/290 (44%), Gaps = 46/290 (15%)
Query: 20 DRAEQAEADKKQAEDRCKQLEEEQQALQKKLKGTEDEVEKYSESVKEAQEKLEQAEKKAT 79
++ ++ E ++ E++ ++ EE+ + ++ + E+++ + E + E +EK+ + E+
Sbjct: 375 EKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMW 434
Query: 80 DAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADES------ERGMKVIENR 133
+ E + L ++ E+E R QE +K+ E EK ++ E ++ E +
Sbjct: 435 EKEEKIRELEEKMH--EQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEK 492
Query: 134 AMKDEEKMELQEMQLKEAKHIAEDSDR--------------KYEEVAR------------ 167
+ EEKM QE ++ E + I E+ R + EE+ R
Sbjct: 493 IREQEEKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKIHEQEEKI 552
Query: 168 ------------KLVILEGELERSEERAEVAESRARQLEEELRTMDQALKSLMASEEEYS 215
K+ E ++ EE+ E + R+ EE++R ++ ++ +E
Sbjct: 553 RKQEEKMWRQEEKMHDQEEKIREQEEKVWRQEEKIREQEEKIREQEEKIREQEEMTQEQE 612
Query: 216 TKEDKYEEEIKLLEEKLKEAETRAEFAERSVAKLEKTIDDLEETLASAKE 265
K + EE++ EEK++E E + E + + EK I + EE + +E
Sbjct: 613 EKMGEQEEKMCEQEEKMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEE 662
Score = 75.9 bits (185), Expect = 4e-14
Identities = 66/269 (24%), Positives = 130/269 (48%), Gaps = 21/269 (7%)
Query: 19 IDRAEQAEADKKQAEDR-CKQLEEEQQALQKKLKGTEDEVEKYSESVKEAQEKLEQAEKK 77
+++A A A +K+ DR ++L +E+ AL +L E+ E + QEKL+ E +
Sbjct: 238 LEQALSAVATQKKKADRYIEELTKERDALSLELYRNTITDEELKEKNAKLQEKLQLVESE 297
Query: 78 ATDAEADVASLNRRIQ-----LVEEELDRAQERLATALQ--------KLEEAE---KAAD 121
++ + +V L R+++ L +++L + L LQ ++EE E +
Sbjct: 298 KSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEENELWNRLNQ 357
Query: 122 ESERGMKVIENRAMKDEEKMELQEMQLKEAKHIAEDSDRKYEEVARKLVILEGELERSEE 181
+ E M E + + EEK++ QE +++E + + + K + E ++ R EE
Sbjct: 358 QQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEE 417
Query: 182 RAEVAESRARQLEEELRTMDQALKSL---MASEEEYSTKEDKYEEEIKLLE-EKLKEAET 237
E + R+ EE + ++ ++ L M +E+ +E+K +EE K+ E EK +E E
Sbjct: 418 MMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEA 477
Query: 238 RAEFAERSVAKLEKTIDDLEETLASAKEE 266
+ E + + E+ I + EE + +E+
Sbjct: 478 KMWRQEEKIREQEEKIREQEEKMWRQEEK 506
Score = 65.9 bits (159), Expect = 4e-11
Identities = 61/262 (23%), Positives = 125/262 (47%), Gaps = 22/262 (8%)
Query: 1 MDAIKKKMQMLKLDKENAIDRAEQAEADKKQAEDRCKQLEEEQQALQKKLKGTEDEVEKY 60
+++ K ++Q+ + + ++RA+ ++Q + L +E Q++ KL+ +E E +
Sbjct: 294 VESEKSEIQLNVKELKRKLERAKLL-LPQQQLQAEADHLGKELQSVSAKLQAQVEENELW 352
Query: 61 SESVKEAQEKLEQAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAA 120
+ ++ +EK+ + E+K IQ EE++ +E++ +K+ E E+
Sbjct: 353 NRLNQQQEEKMWRQEEK--------------IQEWEEKIQEQEEKIREQEEKIREQEEKM 398
Query: 121 DESERGMKVIENRAMKDEEKMELQEMQLKEAKHIAEDSDRKYEEVARKLVILEGELERSE 180
E M E + + EE M +E +++ + + + + K E+ K+ E E+ E
Sbjct: 399 RRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEE 458
Query: 181 ERAE---VAESRARQLEEELRTMDQALKSLMASEEEYSTKEDKYEEEIKLLE-EKLKEAE 236
+R E + E RQ E+E + Q K E+ +E + +E K+ E EK++E E
Sbjct: 459 KRQEEEKIREQEKRQ-EQEAKMWRQEEKIREQEEKIREQEEKMWRQEEKIHEQEKIREEE 517
Query: 237 TRAEFAERSVAKLEKTIDDLEE 258
R E + + + E+ I + EE
Sbjct: 518 KRQE--QEEMWRQEEKIREQEE 537
Score = 53.9 bits (128), Expect = 2e-07
Identities = 56/247 (22%), Positives = 111/247 (44%), Gaps = 26/247 (10%)
Query: 33 EDRCKQLEEEQQALQKKLKGTEDEVEKYSESVKEAQEKLEQAEKKATDAEADVASLNRRI 92
ED K + Q+AL+++L+ + + E Q L ++ E + L R+
Sbjct: 169 EDEQKASHQHQEALRRELEAQVHTIRILTCQKTELQMALYYSQHAVKQLEGEARDLISRL 228
Query: 93 Q---LVEEELDRAQERLATALQK----LEEAEKAAD--ESERGMKVIENRAMKD-----E 138
EL++A +AT +K +EE K D E I + +K+ +
Sbjct: 229 HDSWKFAGELEQALSAVATQKKKADRYIEELTKERDALSLELYRNTITDEELKEKNAKLQ 288
Query: 139 EKMELQEMQLKEAKHIAEDSDRKYEEVARKLVILEGELERSEERAEVAESRARQLEEELR 198
EK++L E + E + ++ RK E KL++ + +L ++ A L +EL+
Sbjct: 289 EKLQLVESEKSEIQLNVKELKRKLERA--KLLLPQQQL----------QAEADHLGKELQ 336
Query: 199 TMDQALKSLMASEEEYSTKEDKYEEEIKLLEEKLKEAETRAEFAERSVAKLEKTIDDLEE 258
++ L++ + E ++ + EE++ EEK++E E + + E + + E+ I + EE
Sbjct: 337 SVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEE 396
Query: 259 TLASAKE 265
+ +E
Sbjct: 397 KMRRQEE 403
Score = 51.6 bits (122), Expect = 8e-07
Identities = 61/252 (24%), Positives = 123/252 (48%), Gaps = 29/252 (11%)
Query: 37 KQLEEEQQALQKKLKGT---EDEVEKYSESVKEAQEKLEQAEKKATDAEADVASLNR-RI 92
KQLE E + L +L + E+E+ +V ++K ++ ++ T E D SL R
Sbjct: 215 KQLEGEARDLISRLHDSWKFAGELEQALSAVATQKKKADRYIEELTK-ERDALSLELYRN 273
Query: 93 QLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIENRAMKDEEKMELQEMQLK-EA 151
+ +EEL +L LQ +E +++SE + V E + + K+ L + QL+ EA
Sbjct: 274 TITDEELKEKNAKLQEKLQLVE-----SEKSEIQLNVKELKRKLERAKLLLPQQQLQAEA 328
Query: 152 KHIAEDSDRKYEEVARKLV--ILEGEL-----ERSEERAEVAESRARQLEEELRTMDQAL 204
H+ ++ + V+ KL + E EL ++ EE+ E + ++ EE+++ ++ +
Sbjct: 329 DHLGKE----LQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKI 384
Query: 205 KSLMASEEEYSTKEDKYEEEIKLLEEKLKEAETRAEFAERSVAKLEKTIDDLEETLASAK 264
+ E+E +E EE+++ EE + E E + E + + E+ + EE + +
Sbjct: 385 R-----EQEEKIREQ--EEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKE 437
Query: 265 EENVEIHQTLDQ 276
E+ E+ + + +
Sbjct: 438 EKIRELEEKMHE 449
Score = 38.1 bits (87), Expect = 0.009
Identities = 19/91 (20%), Positives = 49/91 (53%)
Query: 20 DRAEQAEADKKQAEDRCKQLEEEQQALQKKLKGTEDEVEKYSESVKEAQEKLEQAEKKAT 79
++ + E ++ E + ++ EE+ + ++ ++ E+++ + E + E +EK+++ E+K
Sbjct: 634 EKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMR 693
Query: 80 DAEADVASLNRRIQLVEEELDRAQERLATAL 110
E + R++ EE++ QE L A+
Sbjct: 694 RQEEKMWEQEVRLRQQEEKMQEHQEHLEAAI 724
>gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-like
[Homo sapiens]
Length = 828
Score = 82.0 bits (201), Expect = 5e-16
Identities = 58/247 (23%), Positives = 127/247 (51%), Gaps = 18/247 (7%)
Query: 37 KQLEEEQQALQKKLKGTEDEVEKYSESVKEAQEKLEQA------------EKKATDAEAD 84
++L+++ LQ+KL+ E E + +VKE + KLE+A +++ E +
Sbjct: 183 EELKKKNAELQEKLRLAESEKSEIQLNVKELKRKLERAKFLLPQVQTNTLQEEMWRQEEE 242
Query: 85 VASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIENRAMKDEEKMELQ 144
+ ++I+ EE++ R +ERL K+ E E+ E+ ++ + + ++++EK +
Sbjct: 243 LREQEKKIRKQEEKMWRQEERLREQEGKMREQEEKMRRQEKRLRE-QEKELREQEKELRE 301
Query: 145 EMQLKEAKHIAEDSDRKYEEVARKLVILEGELERSEERAEVAESRARQLEEELRTMDQAL 204
+ +L+E + ++ + K E K+ E ++ R EER E + R+ E+++R ++ +
Sbjct: 302 QKKLREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEERM 361
Query: 205 ----KSLMASEEEYSTKEDKYEEEIKLL-EEKLKEAETRAEFAERSVAKLEKTIDDLEET 259
+ L EE +E +E+E K+ EE+++E E + E ++ + E+ + EE
Sbjct: 362 WEQDERLREKEERMREQEKMWEQEEKMQEEERIREREKKMREEEETMREQEEKMQKQEEN 421
Query: 260 LASAKEE 266
+ +E+
Sbjct: 422 MWEQEEK 428
Score = 81.6 bits (200), Expect = 7e-16
Identities = 52/239 (21%), Positives = 120/239 (50%), Gaps = 6/239 (2%)
Query: 2 DAIKKKMQMLKLDKENAIDRAEQAEADKKQAEDRCKQLEEEQQALQKKLKGTEDEVEKYS 61
+ +++K + ++ K+ + E K Q +++ +EE+ +++++ E ++ +
Sbjct: 514 ERLREKEERMREQKKMWQQEEKMREEKKTQEQEKKTWDQEEKMREEERMREREKKMREEE 573
Query: 62 ESVKEAQEKLEQAEKKATDAEADVASLNRRIQLVEEELDRAQERL--ATALQKLEEAEKA 119
E ++E +EK+++ E+K + E + ++Q EE++ +E++ K++E E+
Sbjct: 574 EMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEEDKMQEQEEM 633
Query: 120 ADESERGMKVIENRAMKDEEKMELQEMQLKEAKHIAEDSDRKYEEVARKLVILEGELERS 179
E E M+ E + + EEKM QE +++E + + + K E K+ E ++
Sbjct: 634 MWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKMREQEEKMQGQEEKMREQ 693
Query: 180 EERAEVAESRARQLEEELRTMDQALKSLMASEEEYSTKEDKYEEEIKLLEEKLKEAETR 238
EE+ E + EE++ ++ M +EE KE++ ++ + ++E+L E E R
Sbjct: 694 EEKMRGQEEKMWGQEEKMWGQEEK----MWGQEEMREKEERIRDQKEKMQERLPEHEER 748
Score = 79.7 bits (195), Expect = 3e-15
Identities = 64/282 (22%), Positives = 133/282 (47%), Gaps = 24/282 (8%)
Query: 7 KMQMLKLDKENAIDRAEQAEADKKQAEDRCKQLEEEQQALQKKLKGTEDEVEKYSESVKE 66
+ Q L KE ++ + E ++K E K ++E+ Q+K ++++ + + + E
Sbjct: 431 QQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWE 490
Query: 67 AQEKLEQAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAAD----- 121
+EK+ E+K D E + + R++ EE + R Q+++ +K+ E +K +
Sbjct: 491 QEEKMRDQEQKMWDQEERMWEQDERLREKEERM-REQKKMWQQEEKMREEKKTQEQEKKT 549
Query: 122 --------------ESERGMKVIENRAMKDEEKMELQEMQLKEAKHIAEDSDRKYEEVAR 167
E E+ M+ E + EEKM+ QE +++E + + + K +E
Sbjct: 550 WDQEEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEE 609
Query: 168 KLVILEGELERSEERAEVAESRARQLEEELRTMDQALKSLMASEEEYSTKEDK---YEEE 224
K+ E ++ EE ++ E E+E + +Q K + EE+ +E+K EE+
Sbjct: 610 KMWEQEEKMWEQEEEDKMQEQEEMMWEQEEKMQEQEEK-MWEQEEKMREQEEKMREQEEK 668
Query: 225 IKLLEEKLKEAETRAEFAERSVAKLEKTIDDLEETLASAKEE 266
++ EEK++E E + + E + + E+ + EE + +E+
Sbjct: 669 MQGQEEKMREQEEKMQGQEEKMREQEEKMRGQEEKMWGQEEK 710
Score = 78.2 bits (191), Expect = 8e-15
Identities = 55/245 (22%), Positives = 122/245 (49%), Gaps = 14/245 (5%)
Query: 14 DKENAIDRAEQAEADKKQAEDRCKQLEEEQQALQKKLKGTEDEVEKYSESVK-EAQEKLE 72
D+E + ++ +K++ K++ ++++ ++++ K E E + + + K +E++
Sbjct: 504 DQEERMWEQDERLREKEERMREQKKMWQQEEKMREEKKTQEQEKKTWDQEEKMREEERMR 563
Query: 73 QAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGM----- 127
+ EKK + E + ++Q EE++ +E++ +K++E E+ E E M
Sbjct: 564 EREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEE 623
Query: 128 --KVIENRAM--KDEEKMELQEMQLKEAKHIAEDSDRKYEEVARKLVILEGELERSEERA 183
K+ E M + EEKM+ QE ++ E + + + K E K+ E ++ EE+
Sbjct: 624 EDKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKMREQEEKM 683
Query: 184 EVAESRARQLEEELRTMDQAL----KSLMASEEEYSTKEDKYEEEIKLLEEKLKEAETRA 239
+ E + R+ EE++R ++ + + + EE+ +E+ E+E ++ ++K K E
Sbjct: 684 QGQEEKMREQEEKMRGQEEKMWGQEEKMWGQEEKMWGQEEMREKEERIRDQKEKMQERLP 743
Query: 240 EFAER 244
E ER
Sbjct: 744 EHEER 748
Score = 77.8 bits (190), Expect = 1e-14
Identities = 59/286 (20%), Positives = 144/286 (50%), Gaps = 14/286 (4%)
Query: 2 DAIKKKMQMLKLDKENAIDRAEQAEADKKQAEDRCKQLEEEQQALQKKLKGTEDEVEKYS 61
+ ++++ + + +E ++ +Q +++ D+ +++ E+ + L++K + ++ + +
Sbjct: 324 EKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEERMWEQDERLREKEERMREQEKMWE 383
Query: 62 ESVK-EAQEKLEQAEKKATDAEADVASLNRRIQLVE------EELDRAQERLATALQKLE 114
+ K + +E++ + EKK + E + ++Q E EE + Q+RL +KL
Sbjct: 384 QEEKMQEEERIREREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLW 443
Query: 115 EAEKAADESERGMKVIENRAMKDEEKMELQEMQLKEAKHIAEDSDRKYEEVARKLVILEG 174
E EK ++ E+ + + ++D+E+M QE ++ + + E D+ +E+ K+ E
Sbjct: 444 EQEKMQEQEEKIWE--QEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQ-EEKMRDQEQ 500
Query: 175 ELERSEERAEVAESRARQLEEELRTMDQALKSLMASEEEYSTKEDK---YEEEIKLL-EE 230
++ EER + R R+ EE +R + + EE T+E + +++E K+ EE
Sbjct: 501 KMWDQEERMWEQDERLREKEERMREQKKMWQQEEKMREEKKTQEQEKKTWDQEEKMREEE 560
Query: 231 KLKEAETRAEFAERSVAKLEKTIDDLEETLASAKEENVEIHQTLDQ 276
+++E E + E + + E+ + + EE + +E+ E + + +
Sbjct: 561 RMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQE 606
Score = 77.4 bits (189), Expect = 1e-14
Identities = 65/245 (26%), Positives = 111/245 (45%), Gaps = 20/245 (8%)
Query: 39 LEEEQQALQKKLKGTEDEVEKYSESVKEAQEKLEQAEKKATDAEADVASLNRRIQLVEEE 98
L+EE +++L+ E ++ K E + +E+L + E K + E + +R++ E+E
Sbjct: 232 LQEEMWRQEEELREQEKKIRKQEEKMWRQEERLREQEGKMREQEEKMRRQEKRLREQEKE 291
Query: 99 LDRAQERLATALQKLEEAEKAADESERGMKVIENRAMKDEEKMELQEMQLKEAKHIAEDS 158
L R QE+ +KL E E+ E E M E + + EEKM QE +L E + +
Sbjct: 292 L-REQEKELREQKKLREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQ 350
Query: 159 DRKYEEVARKLVILEGELERSEERAEVAE----------------SRARQLEEELRTMDQ 202
++K + ++ + L EER E R +++ EE TM +
Sbjct: 351 EQKMRDQEERMWEQDERLREKEERMREQEKMWEQEEKMQEEERIREREKKMREEEETMRE 410
Query: 203 ALKSLMASEEEYSTKEDKYEEEIKLLE--EKLKEAETRAEFAERSVAKLEKTIDDLEETL 260
+ + EE +E+K ++ +L E EKL E E E E + + E+ I D EE
Sbjct: 411 QEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQE-QEEKIWEQEEKIRDQEEMW 469
Query: 261 ASAKE 265
K+
Sbjct: 470 GQEKK 474
Score = 73.9 bits (180), Expect = 1e-13
Identities = 59/254 (23%), Positives = 126/254 (49%), Gaps = 17/254 (6%)
Query: 12 KLDKENAI--DRAEQAEADKKQAEDRCKQLEEEQQAL-----QKKLKGTEDEVEKYSESV 64
+L K+NA ++ AE++K + + K+L+ + + Q + ++E+ + E +
Sbjct: 184 ELKKKNAELQEKLRLAESEKSEIQLNVKELKRKLERAKFLLPQVQTNTLQEEMWRQEEEL 243
Query: 65 KEAQEKLEQAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESE 124
+E ++K+ + E+K E + +++ EE++ R ++RL ++L E EK E +
Sbjct: 244 REQEKKIRKQEEKMWRQEERLREQEGKMREQEEKMRRQEKRLREQEKELREQEKELREQK 303
Query: 125 RGMKVIENRAMKDEEKMELQEMQLKEAKHIAEDSDRKYEEVARKLVILEGELERSEERAE 184
+ ++ E + + EEKM QE +++E + + + E +++ E ++ EER
Sbjct: 304 K-LREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEERMW 362
Query: 185 VAESRARQLEEELRTMDQALKSLMASEEEYSTKEDKYEEEIKLLEEKLKEAETRAEFAER 244
+ R R+ EE +R ++ M +EE +E++ E E+K++E E E
Sbjct: 363 EQDERLREKEERMREQEK-----MWEQEEKMQEEERIRER----EKKMREEEETMREQEE 413
Query: 245 SVAKLEKTIDDLEE 258
+ K E+ + + EE
Sbjct: 414 KMQKQEENMWEQEE 427
Score = 73.9 bits (180), Expect = 1e-13
Identities = 61/275 (22%), Positives = 132/275 (48%), Gaps = 15/275 (5%)
Query: 5 KKKMQMLKLDKENAIDRAEQAEADKKQAE---DRCKQLEEEQQALQKKLKGTEDEVEKYS 61
+KKM + +E EQ E + Q + D+ +++ E+ + L++K + ++ + +
Sbjct: 472 EKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMWEQDERLREKEERMREQKKMWQ 531
Query: 62 ESVKEAQEKLEQAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAAD 121
+ K +EK Q ++K T + + R++ E+++ +E + +K++E E+
Sbjct: 532 QEEKMREEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMR 591
Query: 122 ESERGMKVIENRAMKDEEKMELQEMQLKEAKHIAEDSDRKYEEVARKLVILEGELERSEE 181
E E M E + + EEKM QE ++ E ++ + K +E + E +++ EE
Sbjct: 592 EQEEKMWEQEEKMQEQEEKMWEQEEKMWE-----QEEEDKMQEQEEMMWEQEEKMQEQEE 646
Query: 182 RAEVAESRARQLEEELRTMDQALKSLMASEEEYSTKEDKYEEEIKLLEEKLKEAETRAEF 241
+ E + R+ EE++R ++ ++ EE+ +E+K + + EEK++E E +
Sbjct: 647 KMWEQEEKMREQEEKMREQEEKMQG---QEEKMREQEEKMQGQ----EEKMREQEEKMRG 699
Query: 242 AERSVAKLEKTIDDLEETLASAKEENVEIHQTLDQ 276
E + E+ + EE + +E + + DQ
Sbjct: 700 QEEKMWGQEEKMWGQEEKMWGQEEMREKEERIRDQ 734
Score = 69.3 bits (168), Expect = 4e-12
Identities = 55/287 (19%), Positives = 139/287 (48%), Gaps = 34/287 (11%)
Query: 14 DKENAIDRAEQAEADKKQAEDRCKQLEEEQQAL--QKKLKGTEDEVEKYSESVKEAQEKL 71
++E + + E+ ++++ E + ++L E+++ L Q+K++ E+++ + E +++ +E
Sbjct: 410 EQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMW 469
Query: 72 EQAEK-----KATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERG 126
Q +K K + E + +++ E+++ +ER+ ++L E E+ E ++
Sbjct: 470 GQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMWEQDERLREKEERMREQKKM 529
Query: 127 MKVIE------------------NRAMKDEEKMELQEMQLKEAKHIAEDSDRKYEEVARK 168
+ E M++EE+M +E +++E + + + + K +E K
Sbjct: 530 WQQEEKMREEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQEEKMQEQEEK 589
Query: 169 LVILEGELERSEERAEVAESRARQLEEEL------RTMDQALKSLMASEEEYSTKEDK-- 220
+ E ++ EE+ + E + + EE++ M + + + EE+ +E+K
Sbjct: 590 MREQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEEDKMQEQEEMMWEQEEKMQEQEEKMW 649
Query: 221 -YEEEIKLLEEKLKEAETRAEFAERSVAKLEKTIDDLEETLASAKEE 266
EE+++ EEK++E E + + E + + E+ + EE + +E+
Sbjct: 650 EQEEKMREQEEKMREQEEKMQGQEEKMREQEEKMQGQEEKMREQEEK 696
Score = 68.6 bits (166), Expect = 6e-12
Identities = 66/260 (25%), Positives = 118/260 (45%), Gaps = 43/260 (16%)
Query: 30 KQAEDRCKQLEEEQQALQKKLKGTEDEVEKYSESVKEAQEKLEQAEKKATDAEADVASLN 89
K+A+ ++L +E+ AL +L E+ + E QEKL AE + ++ + +V L
Sbjct: 155 KKADRYIEELTKERDALSLELYRNTITNEELKKKNAELQEKLRLAESEKSEIQLNVKELK 214
Query: 90 RRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIENRAMKDEEKMELQEMQLK 149
R+++ + L + Q T +++ E+ E E+ ++ K EEKM QE +L+
Sbjct: 215 RKLERAKFLLPQVQTN--TLQEEMWRQEEELREQEKKIR-------KQEEKMWRQEERLR 265
Query: 150 EAKHIAEDSDRKYEEVARKLVILEGELERSEERAEVAESRARQLEEELRTMDQAL---KS 206
E EG++ EE+ E R R+ E+ELR ++ L K
Sbjct: 266 EQ---------------------EGKMREQEEKMRRQEKRLREQEKELREQEKELREQKK 304
Query: 207 LMASEEEYSTKEDK-YEEEIKL---------LEEKLKEAETRAEFAERSVAKLEKTIDDL 256
L EE+ +E+K +E+E K+ EE+L E E + E+ + E+ + +
Sbjct: 305 LREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEERMWEQ 364
Query: 257 EETLASAKEENVEIHQTLDQ 276
+E L +E E + +Q
Sbjct: 365 DERLREKEERMREQEKMWEQ 384
Score = 65.5 bits (158), Expect = 5e-11
Identities = 52/257 (20%), Positives = 125/257 (48%), Gaps = 21/257 (8%)
Query: 5 KKKMQMLKLDKENAIDRAEQAEADKKQAEDRCKQLEEEQQALQKKLKGTEDEVEKYSESV 64
+++ +M + +K E E +K+ E + + +EEQ Q E+++ + E +
Sbjct: 273 EQEEKMRRQEKRLREQEKELREQEKELREQKKLREQEEQMQEQ------EEKMWEQEEKM 326
Query: 65 KEAQEKLEQAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESE 124
+E +EK+ + E++ + E + ++++ EE + ERL +++ E EK ++ E
Sbjct: 327 REQEEKMWRQEERLWEQEKQMREQEQKMRDQEERMWEQDERLREKEERMREQEKMWEQEE 386
Query: 125 RGMKVIENRAMKDEEKMELQEMQLKEAKHIAEDSDRKYEEVARKLVILEGELERSEERAE 184
+ M++EE++ +E +++E + + + K ++ + E E+ ++
Sbjct: 387 K---------MQEEERIREREKKMREEEETMREQEEKMQKQEENMWEQE---EKEWQQQR 434
Query: 185 VAESRARQLEEELRTMDQALKSLMASEEEYSTKEDKYEEEIKL-LEEKLKEAETRAEFAE 243
+ E + + E+E M + + + EE+ +E+ + +E K+ +EK++E E + E
Sbjct: 435 LPEQKEKLWEQE--KMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQE 492
Query: 244 RSVAKLEKTIDDLEETL 260
+ E+ + D EE +
Sbjct: 493 EKMRDQEQKMWDQEERM 509
Score = 64.3 bits (155), Expect = 1e-10
Identities = 55/271 (20%), Positives = 124/271 (45%), Gaps = 25/271 (9%)
Query: 14 DKENAIDRAEQAEADKKQAEDRCKQLEEEQQAL---QKKLKGTEDEVEKYSESVKEAQEK 70
++E + E+ ++K+ ++ +Q++E+++ + ++K++ E+++ + E + E +++
Sbjct: 287 EQEKELREQEKELREQKKLREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQ 346
Query: 71 LEQAEKKATDAEADVASLNRRIQLVEEELD------------RAQERLATALQKLEEAEK 118
+ + E+K D E + + R++ EE + + +ER+ +K+ E E+
Sbjct: 347 MREQEQKMRDQEERMWEQDERLREKEERMREQEKMWEQEEKMQEEERIREREKKMREEEE 406
Query: 119 AADESERGMKVIENRAMKDEEKMELQEMQLKEAKHIAEDSDR---------KYEEVARKL 169
E E M+ E + EEK E Q+ +L E K + ++ + EE R
Sbjct: 407 TMREQEEKMQKQEENMWEQEEK-EWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQ 465
Query: 170 VILEGELERSEERAEVAESRARQLEEELRTMDQALKSLMASEEEYSTKEDKYEEEIKLLE 229
+ G+ ++ + ++ E + E+E + DQ K E + E E+E ++ E
Sbjct: 466 EEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMWEQDERLREKEERMRE 525
Query: 230 EKLKEAETRAEFAERSVAKLEKTIDDLEETL 260
+K + E+ + EK D EE +
Sbjct: 526 QKKMWQQEEKMREEKKTQEQEKKTWDQEEKM 556
Score = 57.4 bits (137), Expect = 1e-08
Identities = 40/183 (21%), Positives = 93/183 (50%), Gaps = 5/183 (2%)
Query: 4 IKKKMQMLKLDKENAIDRAEQA-EADKKQAEDRCKQLEEEQQALQKKLK----GTEDEVE 58
++++ +M++ +E ++ E+ E ++K E K E+E++ +++ K ED+++
Sbjct: 569 MREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEEDKMQ 628
Query: 59 KYSESVKEAQEKLEQAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEK 118
+ E + E +EK+++ E+K + E + +++ EE++ +E++ +K++ E+
Sbjct: 629 EQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKMREQEEKMQGQEE 688
Query: 119 AADESERGMKVIENRAMKDEEKMELQEMQLKEAKHIAEDSDRKYEEVARKLVILEGELER 178
E E M+ E + EEKM QE ++ + + E +R ++ + L ER
Sbjct: 689 KMREQEEKMRGQEEKMWGQEEKMWGQEEKMWGQEEMREKEERIRDQKEKMQERLPEHEER 748
Query: 179 SEE 181
E
Sbjct: 749 CSE 751
Score = 32.0 bits (71), Expect = 0.63
Identities = 46/230 (20%), Positives = 92/230 (40%), Gaps = 25/230 (10%)
Query: 75 EKKATDAEADVASLNRRIQLVEEE---LDRAQERLATALQKLEEAEKAADESERG-MKVI 130
EKKA+ + +L R I+ + L + L TAL ++A + ++ G K +
Sbjct: 72 EKKASHQHQE--ALRREIEAQDHTIRILTCQKTELETALYYSQDAARKFEDGNLGESKDL 129
Query: 131 ENRAMKDEEKMELQEMQLKEAKHIAEDSDRKYEEVARKLVILEGELERSEERAEVAESRA 190
R + L + +DR EE+ ++ L EL R+ E + +
Sbjct: 130 AGRLHHSWHFAGELQRALSAVSTWHKKADRYIEELTKERDALSLELYRNTITNEELKKKN 189
Query: 191 RQLEEELRTMDQALKSLMASEEEYSTKEDK-------------------YEEEIKLLEEK 231
+L+E+LR + + + +E K ++ EEE++ E+K
Sbjct: 190 AELQEKLRLAESEKSEIQLNVKELKRKLERAKFLLPQVQTNTLQEEMWRQEEELREQEKK 249
Query: 232 LKEAETRAEFAERSVAKLEKTIDDLEETLASAKEENVEIHQTLDQTLLEL 281
+++ E + E + + E + + EE + ++ E + L + EL
Sbjct: 250 IRKQEEKMWRQEERLREQEGKMREQEEKMRRQEKRLREQEKELREQEKEL 299
>gi|115496169 myosin, heavy chain 7, cardiac muscle, beta [Homo
sapiens]
Length = 1935
Score = 81.3 bits (199), Expect = 9e-16
Identities = 73/284 (25%), Positives = 129/284 (45%), Gaps = 30/284 (10%)
Query: 4 IKKKMQMLKLDKENAIDRAEQAEADK-KQAEDRCKQLEEEQQALQKKLKGTEDEVEKYSE 62
+++KM L L ++N + QAE D AE+RC QL + + L+ K+K + +E E
Sbjct: 873 LEEKMVSL-LQEKNDLQLQVQAEQDNLADAEERCDQLIKNKIQLEAKVKEMNERLEDEEE 931
Query: 63 SVKEAQEKLEQAEKKATDAEADVASLNRRIQLVEEE-----------------LDRAQER 105
E K + E + ++ + D+ L + VE+E LD +
Sbjct: 932 MNAELTAKKRKLEDECSELKRDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDEIIAK 991
Query: 106 LATALQKLEEAEKAADESERGMKVIENRAMKDEEKMELQ----EMQLKEAKHIAEDSDRK 161
L + L+EA + A + + + N K + K+E Q E L++ K + D +R
Sbjct: 992 LTKEKKALQEAHQQALDDLQAEEDKVNTLTKAKVKLEQQVDDLEGSLEQEKKVRMDLERA 1051
Query: 162 YEEVARKLVILEGELERSEERAEVAESRARQLEEELRTMDQALKSLMASEEEYSTKEDKY 221
+ LEG+L+ ++E E+ +QL+E L+ D L +L A E+ +
Sbjct: 1052 KRK-------LEGDLKLTQESIMDLENDKQQLDERLKKKDFELNALNARIEDEQALGSQL 1104
Query: 222 EEEIKLLEEKLKEAETRAEFAERSVAKLEKTIDDLEETLASAKE 265
++++K L+ +++E E E + AK+EK DL L E
Sbjct: 1105 QKKLKELQARIEELEEELEAERTARAKVEKLRSDLSRELEEISE 1148
Score = 73.9 bits (180), Expect = 1e-13
Identities = 62/307 (20%), Positives = 141/307 (45%), Gaps = 33/307 (10%)
Query: 5 KKKMQMLKLDKENAIDRAEQAEADKKQAEDRCKQLEEEQQALQKKLKGTEDEVEKYSE-- 62
+K+M +K + + E++EA +K+ E++ L +E+ LQ +++ +D + E
Sbjct: 846 EKEMASMKEEFTRLKEALEKSEARRKELEEKMVSLLQEKNDLQLQVQAEQDNLADAEERC 905
Query: 63 ------------SVKEAQEKLEQAEKKATDAEADVASLNRRIQLVEEELDRAQERLATAL 110
VKE E+LE E + A++ + R+++ EL R + L L
Sbjct: 906 DQLIKNKIQLEAKVKEMNERLEDEE----EMNAELTAKKRKLEDECSELKRDIDDLELTL 961
Query: 111 QKLEEAEKAAD-------ESERGMKVI------ENRAMKDEEKMELQEMQLKEAKHIAED 157
K+E+ + A + E G+ I E +A+++ + L ++Q +E K
Sbjct: 962 AKVEKEKHATENKVKNLTEEMAGLDEIIAKLTKEKKALQEAHQQALDDLQAEEDK--VNT 1019
Query: 158 SDRKYEEVARKLVILEGELERSEERAEVAESRARQLEEELRTMDQALKSLMASEEEYSTK 217
+ ++ +++ LEG LE+ ++ E R+LE +L+ +++ L +++ +
Sbjct: 1020 LTKAKVKLEQQVDDLEGSLEQEKKVRMDLERAKRKLEGDLKLTQESIMDLENDKQQLDER 1079
Query: 218 EDKYEEEIKLLEEKLKEAETRAEFAERSVAKLEKTIDDLEETLASAKEENVEIHQTLDQT 277
K + E+ L ++++ + ++ + +L+ I++LEE L + + ++ +
Sbjct: 1080 LKKKDFELNALNARIEDEQALGSQLQKKLKELQARIEELEEELEAERTARAKVEKLRSDL 1139
Query: 278 LLELNNL 284
EL +
Sbjct: 1140 SRELEEI 1146
Score = 72.4 bits (176), Expect = 4e-13
Identities = 64/291 (21%), Positives = 134/291 (46%), Gaps = 40/291 (13%)
Query: 1 MDAIKKKMQMLKLDKENAIDRAE-------------QAEADKKQAEDRCKQLEEEQQALQ 47
++ ++K+++ K++ ++A++ AE Q E ++ +AE K E++++ Q
Sbjct: 1526 LEKVRKQLEAEKMELQSALEEAEASLEHEEGKILRAQLEFNQIKAEIERKLAEKDEEMEQ 1585
Query: 48 KK------LKGTEDEVEKYSESVKEAQEKLEQAEKKATDAEADVASLNRRIQLVEEELDR 101
K + + ++ + S EA ++ E + E ++ NR ++++
Sbjct: 1586 AKRNHLRVVDSLQTSLDAETRSRNEALRVKKKMEGDLNEMEIQLSHANRMAAEAQKQVKS 1645
Query: 102 AQERLATALQKLEEAEKAADESERGMKVIENRAMKDEEKMELQEMQLKEAKHIAEDSDRK 161
Q L +L++A +A D+ + + ++E R L + +L+E + + E ++R
Sbjct: 1646 LQSLLKDTQIQLDDAVRANDDLKENIAIVERRN-------NLLQAELEELRAVVEQTER- 1697
Query: 162 YEEVARKLVILEGELERSEERAEVAESRARQLEEELRTMDQALKSLMASEEEYSTKEDKY 221
+RKL E EL + ER ++ S+ L + + MD L L EE +
Sbjct: 1698 ----SRKLA--EQELIETSERVQLLHSQNTSLINQKKKMDADLSQLQTEVEEAVQECRNA 1751
Query: 222 EEEIK-------LLEEKLKEAETRAEFAERSVAKLEKTIDDLEETLASAKE 265
EE+ K ++ E+LK+ + + ER +E+TI DL+ L A++
Sbjct: 1752 EEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTIKDLQHRLDEAEQ 1802
Score = 69.3 bits (168), Expect = 4e-12
Identities = 47/199 (23%), Positives = 100/199 (50%), Gaps = 5/199 (2%)
Query: 5 KKKMQ----MLKLDKENAIDRAEQAEADKKQAEDRCKQLEEEQQALQKKLKGTEDEVEKY 60
KKKM L+ + E A+ AE K+A + EE + Q E +
Sbjct: 1727 KKKMDADLSQLQTEVEEAVQECRNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNM 1786
Query: 61 SESVKEAQEKLEQAEKKATDA-EADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKA 119
+++K+ Q +L++AE+ A + + L R++ +E EL+ Q+R A +++ + ++E+
Sbjct: 1787 EQTIKDLQHRLDEAEQIALKGGKKQLQKLEARVRELENELEAEQKRNAESVKGMRKSERR 1846
Query: 120 ADESERGMKVIENRAMKDEEKMELQEMQLKEAKHIAEDSDRKYEEVARKLVILEGELERS 179
E + ++ ++ ++ ++++K K AE+++ + K ++ EL+ +
Sbjct: 1847 IKELTYQTEEDRKNLLRLQDLVDKLQLKVKAYKRQAEEAEEQANTNLSKFRKVQHELDEA 1906
Query: 180 EERAEVAESRARQLEEELR 198
EERA++AES+ +L + R
Sbjct: 1907 EERADIAESQVNKLRAKSR 1925
Score = 68.9 bits (167), Expect = 5e-12
Identities = 60/261 (22%), Positives = 115/261 (44%), Gaps = 24/261 (9%)
Query: 30 KQAEDRCKQLEEE---QQALQKKLKGTEDEVEKYSESVKEAQEKLEQAEKKATDAEADVA 86
+Q ED +QLEEE + AL L+ + + E +E E + ++ + A ++VA
Sbjct: 1310 QQLEDLKRQLEEEVKAKNALAHALQSARHDCDLLREQYEEETEAKAELQRVLSKANSEVA 1369
Query: 87 SLNRRIQLVE----EELDRAQERLATALQKLEEAEKAADESERGMKVIENRAMKDEEKME 142
+ + EEL+ A+++LA Q+L+EAE+A + +E + + ++E
Sbjct: 1370 QWRTKYETDAIQRTEELEEAKKKLA---QRLQEAEEAVEAVNAKCSSLEKTKHRLQNEIE 1426
Query: 143 LQEMQLKEAKHIAEDSDRKYEEVARKLVILEGELERSEERAEVAESRARQLEEELRTMDQ 202
+ ++ + A D+K + L + + E S+ E ++ AR L EL +
Sbjct: 1427 DLMVDVERSNAAAAALDKKQRNFDKILAEWKQKYEESQSELESSQKEARSLSTELFKLKN 1486
Query: 203 ALKSLMASEEEYSTKEDKYEEEIKLLEEKLKEAETRAEFAERSVAKLEKTIDDLEETLAS 262
A + + E + + +EEI L E+L + KTI +LE+
Sbjct: 1487 AYEESLEHLETFKRENKNLQEEISDLTEQLGSS--------------GKTIHELEKVRKQ 1532
Query: 263 AKEENVEIHQTLDQTLLELNN 283
+ E +E+ L++ L +
Sbjct: 1533 LEAEKMELQSALEEAEASLEH 1553
Score = 67.4 bits (163), Expect = 1e-11
Identities = 69/304 (22%), Positives = 130/304 (42%), Gaps = 41/304 (13%)
Query: 2 DAIKKKMQMLKLDKENAIDRAEQAEADKKQAEDRCKQLEEEQQALQKKLKGTEDEVEK-- 59
DAI++ ++ + K+ A R ++AE + +C LE+ + LQ +++ +VE+
Sbjct: 1378 DAIQRTEELEEAKKKLA-QRLQEAEEAVEAVNAKCSSLEKTKHRLQNEIEDLMVDVERSN 1436
Query: 60 -------------------YSESVKEAQEKLEQAEKKATDAEADVASLN-------RRIQ 93
+ + +E+Q +LE ++K+A ++ L ++
Sbjct: 1437 AAAAALDKKQRNFDKILAEWKQKYEESQSELESSQKEARSLSTELFKLKNAYEESLEHLE 1496
Query: 94 LVEEELDRAQERLATALQKLEEAEKAADESERGMKVIENRAMKDEEKMELQEMQLKEAKH 153
+ E QE ++ ++L + K E E+ K +E EKMELQ L+EA+
Sbjct: 1497 TFKRENKNLQEEISDLTEQLGSSGKTIHELEKVRKQLE------AEKMELQS-ALEEAEA 1549
Query: 154 IAEDSDRKYEEVARKLVILEGELERSEERAEVAESRARQLEEELRTMDQALKSLMA---S 210
E + K + ++ E+ER + AE E + LR +D SL A S
Sbjct: 1550 SLEHEEGKILRAQLEFNQIKAEIER--KLAEKDEEMEQAKRNHLRVVDSLQTSLDAETRS 1607
Query: 211 EEEYSTKEDKYEEEIKLLEEKLKEAETRAEFAERSVAKLEKTIDDLEETLASAKEENVEI 270
E + K E ++ +E +L A A A++ V L+ + D + L A N ++
Sbjct: 1608 RNEALRVKKKMEGDLNEMEIQLSHANRMAAEAQKQVKSLQSLLKDTQIQLDDAVRANDDL 1667
Query: 271 HQTL 274
+ +
Sbjct: 1668 KENI 1671
Score = 64.7 bits (156), Expect = 9e-11
Identities = 60/224 (26%), Positives = 108/224 (48%), Gaps = 24/224 (10%)
Query: 56 EVEKYSESVKEAQEKLEQAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEE 115
E EK S+KE +L++A +K+ EA RR +L E+ + QE+ LQ E
Sbjct: 844 EREKEMASMKEEFTRLKEALEKS---EA------RRKELEEKMVSLLQEKNDLQLQVQAE 894
Query: 116 AEKAADESERGMKVIENRAMKDEEKMELQEMQLKEAKHIAEDSDRKYE------EVARKL 169
+ AD ER ++I+N+ + + E+ E E + AE + +K + E+ R +
Sbjct: 895 QDNLADAEERCDQLIKNKIQLEAKVKEMNERLEDEEEMNAELTAKKRKLEDECSELKRDI 954
Query: 170 VILEGELERSEERAEVAESRARQLEEELRTMDQALKSLMASEEEYSTKEDK-YEEEIKLL 228
LE L + E+ E++ + L EE+ +D+ + L TKE K +E +
Sbjct: 955 DDLELTLAKVEKEKHATENKVKNLTEEMAGLDEIIAKL--------TKEKKALQEAHQQA 1006
Query: 229 EEKLKEAETRAEFAERSVAKLEKTIDDLEETLASAKEENVEIHQ 272
+ L+ E + ++ KLE+ +DDLE +L K+ +++ +
Sbjct: 1007 LDDLQAEEDKVNTLTKAKVKLEQQVDDLEGSLEQEKKVRMDLER 1050
Score = 63.2 bits (152), Expect = 3e-10
Identities = 49/254 (19%), Positives = 112/254 (44%), Gaps = 1/254 (0%)
Query: 4 IKKKMQMLKLDKENAIDRAEQAEADKKQAEDRCKQLEEEQQALQKKLKGTEDEVEKYSES 63
++++ +L+ + E EQ E +K AE + E Q L + ++ +K
Sbjct: 1674 VERRNNLLQAELEELRAVVEQTERSRKLAEQELIETSERVQLLHSQNTSLINQKKKMDAD 1733
Query: 64 VKEAQEKLEQAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADES 123
+ + Q ++E+A ++ +AE ++ EEL + Q+ A + + E+ +
Sbjct: 1734 LSQLQTEVEEAVQECRNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTIKDL 1793
Query: 124 ERGMKVIENRAMKDEEK-MELQEMQLKEAKHIAEDSDRKYEEVARKLVILEGELERSEER 182
+ + E A+K +K ++ E +++E ++ E ++ E + + E ++ +
Sbjct: 1794 QHRLDEAEQIALKGGKKQLQKLEARVRELENELEAEQKRNAESVKGMRKSERRIKELTYQ 1853
Query: 183 AEVAESRARQLEEELRTMDQALKSLMASEEEYSTKEDKYEEEIKLLEEKLKEAETRAEFA 242
E +L++ + + +K+ EE + + + + ++ +L EAE RA+ A
Sbjct: 1854 TEEDRKNLLRLQDLVDKLQLKVKAYKRQAEEAEEQANTNLSKFRKVQHELDEAEERADIA 1913
Query: 243 ERSVAKLEKTIDDL 256
E V KL D+
Sbjct: 1914 ESQVNKLRAKSRDI 1927
Score = 62.0 bits (149), Expect = 6e-10
Identities = 59/306 (19%), Positives = 119/306 (38%), Gaps = 30/306 (9%)
Query: 4 IKKKMQMLKLDKENAIDRAEQAEADKKQAEDRCKQLEEEQQALQKKLKGTEDEVEKYSES 63
++K+ KL+ ++ EQ K E C+ LE++ + K + T+ V +
Sbjct: 1217 LEKEKSEFKLELDDVTSNMEQIIKAKANLEKMCRTLEDQMNEHRSKAEETQRSVNDLTSQ 1276
Query: 64 VKEAQEKLEQAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADES 123
+ Q + + ++ + EA ++ L R ++L+ + +L ++ A +
Sbjct: 1277 RAKLQTENGELSRQLDEKEALISQLTRGKLTYTQQLEDLKRQLEEEVKAKNALAHALQSA 1336
Query: 124 ERGMKVI-ENRAMKDEEKMELQEMQLKEAKHIAE-------DSDRKYEEVARKLVILEGE 175
++ E + E K ELQ + K +A+ D+ ++ EE+ L
Sbjct: 1337 RHDCDLLREQYEEETEAKAELQRVLSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQR 1396
Query: 176 LERSEERAEVAESRARQLEEELRTMDQALKSLMASEEEYSTK------------------ 217
L+ +EE E ++ LE+ + ++ LM E +
Sbjct: 1397 LQEAEEAVEAVNAKCSSLEKTKHRLQNEIEDLMVDVERSNAAAAALDKKQRNFDKILAEW 1456
Query: 218 EDKYEEEIKLLEEKLKEAETRAEFAERSVAKLEKTIDDLEETLASAKEENVEIHQTLDQT 277
+ KYEE LE KEA + + KL+ ++ E L + K EN + + +
Sbjct: 1457 KQKYEESQSELESSQKEARS----LSTELFKLKNAYEESLEHLETFKRENKNLQEEISDL 1512
Query: 278 LLELNN 283
+L +
Sbjct: 1513 TEQLGS 1518
Score = 61.2 bits (147), Expect = 1e-09
Identities = 65/314 (20%), Positives = 133/314 (42%), Gaps = 60/314 (19%)
Query: 12 KLDKEN-AIDRAEQAEADKKQAE-DRCKQLEEEQQALQKKLKGTEDEVEKYSESVKEAQE 69
KL KE A+ A Q D QAE D+ L + + L++++ D++E E K+ +
Sbjct: 991 KLTKEKKALQEAHQQALDDLQAEEDKVNTLTKAKVKLEQQV----DDLEGSLEQEKKVRM 1046
Query: 70 KLEQAEKKATD----AEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESER 125
LE+A++K + + L Q ++E L + L ++E+ + + ++
Sbjct: 1047 DLERAKRKLEGDLKLTQESIMDLENDKQQLDERLKKKDFELNALNARIEDEQALGSQLQK 1106
Query: 126 GMKVIENRAMKDEEKMELQEMQLKEAKHIAEDSDRKYEEVARKLVILEG----ELERSEE 181
+K ++ R + EE++E + + + + D R+ EE++ +L G ++E +++
Sbjct: 1107 KLKELQARIEELEEELEAERTARAKVEKLRSDLSRELEEISERLEEAGGATSVQIEMNKK 1166
Query: 182 RAEVAESRARQLE-------------------------EELRTMDQALKSLMASEEEYST 216
R + R LE E++ + + + L + E+
Sbjct: 1167 REAEFQKMRRDLEEATLQHEATAAALRKKHADSVAELGEQIDNLQRVKQKLEKEKSEFKL 1226
Query: 217 KED--------------KYEEEIKLLEEKLKEAETRAEFAERSVAKLEKTIDDLEETLAS 262
+ D E+ + LE+++ E ++AE +RSV +DL A
Sbjct: 1227 ELDDVTSNMEQIIKAKANLEKMCRTLEDQMNEHRSKAEETQRSV-------NDLTSQRAK 1279
Query: 263 AKEENVEIHQTLDQ 276
+ EN E+ + LD+
Sbjct: 1280 LQTENGELSRQLDE 1293
Score = 58.5 bits (140), Expect = 6e-09
Identities = 50/265 (18%), Positives = 121/265 (45%), Gaps = 16/265 (6%)
Query: 29 KKQAEDRCKQLEEEQQALQKKLKGTEDEVEKYSESVKEAQEKLEQAEKKATDAEADVASL 88
KK+ E ++E + + + +V+ +K+ Q +L+ A + D + ++A +
Sbjct: 1615 KKKMEGDLNEMEIQLSHANRMAAEAQKQVKSLQSLLKDTQIQLDDAVRANDDLKENIAIV 1674
Query: 89 NRRIQLVEEELDRAQERLATALQKLEEAEKAAD----ESERGMKVIENR---AMKDEEKM 141
RR L++ EL E L +++ E + K A+ E+ ++++ ++ + ++KM
Sbjct: 1675 ERRNNLLQAEL----EELRAVVEQTERSRKLAEQELIETSERVQLLHSQNTSLINQKKKM 1730
Query: 142 ELQEMQLKEAKHIAEDSDRKYEEVARKLV----ILEGELERSEERAEVAESRARQLEEEL 197
+ QL+ A R EE A+K + ++ EL++ ++ + E + +E+ +
Sbjct: 1731 DADLSQLQTEVEEAVQECRNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTI 1790
Query: 198 RTMDQALKSLMASEEEYSTKE-DKYEEEIKLLEEKLKEAETRAEFAERSVAKLEKTIDDL 256
+ + L + K+ K E ++ LE +L+ + R + + + K E+ I +L
Sbjct: 1791 KDLQHRLDEAEQIALKGGKKQLQKLEARVRELENELEAEQKRNAESVKGMRKSERRIKEL 1850
Query: 257 EETLASAKEENVEIHQTLDQTLLEL 281
++ + + +D+ L++
Sbjct: 1851 TYQTEEDRKNLLRLQDLVDKLQLKV 1875
Score = 44.3 bits (103), Expect = 1e-04
Identities = 35/127 (27%), Positives = 63/127 (49%), Gaps = 21/127 (16%)
Query: 161 KYEEVARKLVILEGELERSEERAEVAESRARQLEEELRTMDQALKSL----MASEEEYST 216
K E +++ ++ E R +E E +E+R ++LEE++ ++ Q L A ++ +
Sbjct: 841 KSAEREKEMASMKEEFTRLKEALEKSEARRKELEEKMVSLLQEKNDLQLQVQAEQDNLAD 900
Query: 217 KEDKYEEEIK---LLEEKLKEAETRAEFAER--------------SVAKLEKTIDDLEET 259
E++ ++ IK LE K+KE R E E ++L++ IDDLE T
Sbjct: 901 AEERCDQLIKNKIQLEAKVKEMNERLEDEEEMNAELTAKKRKLEDECSELKRDIDDLELT 960
Query: 260 LASAKEE 266
LA ++E
Sbjct: 961 LAKVEKE 967
Score = 41.2 bits (95), Expect = 0.001
Identities = 35/131 (26%), Positives = 67/131 (51%), Gaps = 15/131 (11%)
Query: 5 KKKMQMLK-----LDKENAIDRAEQAEADK--KQAEDRCKQLEEEQQALQKKLKGTEDEV 57
KK++Q L+ L+ E ++ AE+ K +++E R K+L + + +K L +D V
Sbjct: 1809 KKQLQKLEARVRELENELEAEQKRNAESVKGMRKSERRIKELTYQTEEDRKNLLRLQDLV 1868
Query: 58 EKYSESVKEAQEKLEQAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAE 117
+K VK + + E+AE++A + + + V+ ELD A+ER A ++ +
Sbjct: 1869 DKLQLKVKAYKRQAEEAEEQANTNLS-------KFRKVQHELDEAEERADIAESQVNKLR 1921
Query: 118 -KAADESERGM 127
K+ D +G+
Sbjct: 1922 AKSRDIGTKGL 1932
Score = 32.0 bits (71), Expect = 0.63
Identities = 22/96 (22%), Positives = 46/96 (47%), Gaps = 14/96 (14%)
Query: 189 RARQLEEELRTMDQALKSLMASEEEYSTKEDKYEEE-IKLLEEK-------------LKE 234
++ + E+E+ +M + L + E+ + + EE+ + LL+EK L +
Sbjct: 841 KSAEREKEMASMKEEFTRLKEALEKSEARRKELEEKMVSLLQEKNDLQLQVQAEQDNLAD 900
Query: 235 AETRAEFAERSVAKLEKTIDDLEETLASAKEENVEI 270
AE R + ++ +LE + ++ E L +E N E+
Sbjct: 901 AEERCDQLIKNKIQLEAKVKEMNERLEDEEEMNAEL 936
>gi|153945790 myosin, heavy chain 8, skeletal muscle, perinatal [Homo
sapiens]
Length = 1937
Score = 81.3 bits (199), Expect = 9e-16
Identities = 69/284 (24%), Positives = 132/284 (46%), Gaps = 30/284 (10%)
Query: 4 IKKKMQMLKLDKENAIDRAEQAEADK-KQAEDRCKQLEEEQQALQKKLKGTEDEVEKYSE 62
+++KM L L ++N + Q+EAD AE+RC+QL + + L+ K+K + E+ E
Sbjct: 876 LEEKMVTL-LKEKNDLQLQVQSEADSLADAEERCEQLIKNKIQLEAKIKEVTERAEEEEE 934
Query: 63 SVKEAQEKLEQAEKKATDAEADVASLNRRIQLVEEELDRAQER----------LATALQK 112
E K + E + ++ + D+ L + VE+E + + L + K
Sbjct: 935 INAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDETIAK 994
Query: 113 LEEAEKAADES-----------ERGMKVIENRAMKDEEKMELQEMQLKEAKHIAEDSDRK 161
L + +KA E+ E + ++ K E++++ E L++ K + D +R
Sbjct: 995 LSKEKKALQETHQQTLDDLQAEEDKVNILTKAKTKLEQQVDDLEGSLEQEKKLRMDLERA 1054
Query: 162 YEEVARKLVILEGELERSEERAEVAESRARQLEEELRTMDQALKSLMASEEEYSTKEDKY 221
+ LEG+L+ ++E E+ +QL+E+L + + +L++ E+ E +
Sbjct: 1055 KRK-------LEGDLKLAQESTMDMENDKQQLDEKLEKKEFEISNLISKIEDEQAVEIQL 1107
Query: 222 EEEIKLLEEKLKEAETRAEFAERSVAKLEKTIDDLEETLASAKE 265
+++IK L+ +++E E S AK EK DL L E
Sbjct: 1108 QKKIKELQARIEELGEEIEAERASRAKAEKQRSDLSRELEEISE 1151
Score = 70.5 bits (171), Expect = 2e-12
Identities = 50/199 (25%), Positives = 99/199 (49%), Gaps = 5/199 (2%)
Query: 5 KKKMQ----MLKLDKENAIDRAEQAEADKKQAEDRCKQLEEEQQALQKKLKGTEDEVEKY 60
KKK++ L+ + E I + AE K+A + EE + Q E +
Sbjct: 1730 KKKLENDVSQLQSEVEEVIQESRNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNL 1789
Query: 61 SESVKEAQEKLEQAEKKATDA-EADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKA 119
++VK+ Q +L++AE+ A + + L R++ +E E++ Q+R A A++ L + E+
Sbjct: 1790 EQTVKDLQHRLDEAEQLALKGGKKQIQKLEARVRELEGEVENEQKRNAEAVKGLRKHERR 1849
Query: 120 ADESERGMKVIENRAMKDEEKMELQEMQLKEAKHIAEDSDRKYEEVARKLVILEGELERS 179
E + ++ ++ ++ + ++K K AE+++ + K L+ ELE +
Sbjct: 1850 VKELTYQTEEDRKNVLRLQDLVDKLQAKVKSYKRQAEEAEEQSNANLSKFRKLQHELEEA 1909
Query: 180 EERAEVAESRARQLEEELR 198
EERA++AES+ +L + R
Sbjct: 1910 EERADIAESQVNKLRVKSR 1928
Score = 68.2 bits (165), Expect = 8e-12
Identities = 57/254 (22%), Positives = 115/254 (45%), Gaps = 15/254 (5%)
Query: 4 IKKKMQMLKLDKENAIDRAEQAEADKKQAE-------DRCKQLEEEQQALQKKLKGTEDE 56
++++ +L+ + E EQ E +K AE +R + L + +L K E++
Sbjct: 1677 VERRANLLQAEIEELWATLEQTERSRKIAEQELLDASERVQLLHTQNTSLINTKKKLEND 1736
Query: 57 VEKYSESVKEAQEKLEQAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEA 116
V + V+E ++ AE+KA A D A ++ EEL + Q+ A + +
Sbjct: 1737 VSQLQSEVEEVIQESRNAEEKAKKAITDAA-------MMAEELKKEQDTSAHLERMKKNL 1789
Query: 117 EKAADESERGMKVIENRAMKDEEK-MELQEMQLKEAKHIAEDSDRKYEEVARKLVILEGE 175
E+ + + + E A+K +K ++ E +++E + E+ ++ E + L E
Sbjct: 1790 EQTVKDLQHRLDEAEQLALKGGKKQIQKLEARVRELEGEVENEQKRNAEAVKGLRKHERR 1849
Query: 176 LERSEERAEVAESRARQLEEELRTMDQALKSLMASEEEYSTKEDKYEEEIKLLEEKLKEA 235
++ + E +L++ + + +KS EE + + + + L+ +L+EA
Sbjct: 1850 VKELTYQTEEDRKNVLRLQDLVDKLQAKVKSYKRQAEEAEEQSNANLSKFRKLQHELEEA 1909
Query: 236 ETRAEFAERSVAKL 249
E RA+ AE V KL
Sbjct: 1910 EERADIAESQVNKL 1923
Score = 62.8 bits (151), Expect = 3e-10
Identities = 59/254 (23%), Positives = 122/254 (48%), Gaps = 14/254 (5%)
Query: 38 QLEEEQQALQKKLKGTEDEVEKYSESVKEAQEKLEQAEKKATDAEADVASLNRRIQLVEE 97
+ E+E ++++ + T+DE+ K KE +EK+ K+ D + V S + EE
Sbjct: 847 ETEKEMATMKEEFQKTKDELAKSEAKRKELEEKMVTLLKEKNDLQLQVQSEADSLADAEE 906
Query: 98 ELDRAQERLATALQKLEEAEKAADESERGMKVIENRAMKDEEKMELQEMQLKEAKHIAED 157
++ + K++E + A+E E E A +K +L++ + E K +D
Sbjct: 907 RCEQLIKNKIQLEAKIKEVTERAEEEE------EINAELTAKKRKLED-ECSELKKDIDD 959
Query: 158 SDRKYEEVARKLVILEGELER-SEERAEVAESRARQLEEE---LRTMDQALKSLMASEEE 213
+ +V ++ E +++ +EE A + E+ A+ +E+ T Q L L A E++
Sbjct: 960 LELTLAKVEKEKHATENKVKNLTEEMAGLDETIAKLSKEKKALQETHQQTLDDLQAEEDK 1019
Query: 214 YS--TK-EDKYEEEIKLLEEKLKEAETRAEFAERSVAKLEKTIDDLEETLASAKEENVEI 270
+ TK + K E+++ LE L++ + ER+ KLE + +E+ + + ++
Sbjct: 1020 VNILTKAKTKLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGDLKLAQESTMDMENDKQQL 1079
Query: 271 HQTLDQTLLELNNL 284
+ L++ E++NL
Sbjct: 1080 DEKLEKKEFEISNL 1093
Score = 62.4 bits (150), Expect = 4e-10
Identities = 57/282 (20%), Positives = 126/282 (44%), Gaps = 12/282 (4%)
Query: 12 KLDKENAI--DRAEQAEADKKQAEDRCKQLEEE---QQALQKKLKGTEDEVEKYSESVKE 66
+LD+++A+ + +A +Q E+ QLEEE + AL L+ + + + E +E
Sbjct: 1293 QLDEKDALVSQLSRSKQASTQQIEELKHQLEEETKAKNALAHALQSSRHDCDLLREQYEE 1352
Query: 67 AQEKLEQAEKKATDAEADVASLNRRIQLVE----EELDRAQERLATALQKLEEAEKAADE 122
QE + ++ + A ++VA + + EEL+ A+++LA Q+L+EAE+ +
Sbjct: 1353 EQEGKAELQRALSKANSEVAQWRTKYETDAIQRTEELEEAKKKLA---QRLQEAEEHVEA 1409
Query: 123 SERGMKVIENRAMKDEEKMELQEMQLKEAKHIAEDSDRKYEEVARKLVILEGELERSEER 182
+E + + ++E + ++ + D+K + L + + E ++
Sbjct: 1410 VNAKCASLEKTKQRLQNEVEDLMLDVERSNAACAALDKKQRNFDKVLSEWKQKYEETQAE 1469
Query: 183 AEVAESRARQLEEELRTMDQALKSLMASEEEYSTKEDKYEEEIKLLEEKLKEAETRAEFA 242
E ++ +R L EL + + + E + ++EI L E++ E +
Sbjct: 1470 LEASQKESRSLSTELFKVKNVYEESLDQLETLRRENKNLQQEISDLTEQIAEGGKQIHEL 1529
Query: 243 ERSVAKLEKTIDDLEETLASAKEENVEIHQTLDQTLLELNNL 284
E+ ++E+ +++ L A+ + + LELN +
Sbjct: 1530 EKIKKQVEQEKCEIQAALEEAEASLEHEEGKILRIQLELNQV 1571
Score = 62.0 bits (149), Expect = 6e-10
Identities = 63/294 (21%), Positives = 125/294 (42%), Gaps = 28/294 (9%)
Query: 11 LKLDKENAIDRAEQAEADKKQAEDRCKQLEEEQQALQKKLKGTEDEVEKYSESVKEAQEK 70
L++D E A + E D K A++ +E ++Q L +KL+ E E+ +++ Q
Sbjct: 1047 LRMDLERA---KRKLEGDLKLAQESTMDMENDKQQLDEKLEKKEFEISNLISKIEDEQAV 1103
Query: 71 LEQAEKKATDAEADVASLNRRIQL----------VEEELDRAQERLATALQKLEEAEKAA 120
Q +KK + +A + L I+ +L R E ++ L++ A A
Sbjct: 1104 EIQLQKKIKELQARIEELGEEIEAERASRAKAEKQRSDLSRELEEISERLEEAGGATSAQ 1163
Query: 121 DESERGMKVIENRAMKDEEKMELQE------MQLKEAKHIAEDSDR--KYEEVARKLVIL 172
E + + + +D E+ LQ ++ K A +AE ++ + V +KL
Sbjct: 1164 VELNKKREAEFQKLRRDLEEATLQHEAMVAALRKKHADSMAELGEQIDNLQRVKQKL--- 1220
Query: 173 EGELERSEERAEVAE--SRARQLEEELRTMDQALKSLMASEEEYSTKEDKYEEEIKLLEE 230
E E+SE + E + S A + + +++ +SL E TKE++ + I L
Sbjct: 1221 --EKEKSELKMETDDLSSNAEAISKAKGNLEKMCRSLEDQVSELKTKEEEQQRLINDLTA 1278
Query: 231 KLKEAETRAEFAERSVAKLEKTIDDLEETLASAKEENVEIHQTLDQTLLELNNL 284
+ +T A R + + + + L + ++ ++ E+ L++ N L
Sbjct: 1279 QRARLQTEAGEYSRQLDEKDALVSQLSRSKQASTQQIEELKHQLEEETKAKNAL 1332
Score = 60.5 bits (145), Expect = 2e-09
Identities = 50/293 (17%), Positives = 124/293 (42%), Gaps = 22/293 (7%)
Query: 4 IKKKMQMLKLDKENAIDRAEQAEADKKQAEDRCKQLEEEQQALQKKLKGTEDEVEKYSES 63
++K+ LK++ ++ AE K E C+ LE++ L+ K + + + +
Sbjct: 1220 LEKEKSELKMETDDLSSNAEAISKAKGNLEKMCRSLEDQVSELKTKEEEQQRLINDLTAQ 1279
Query: 64 VKEAQEKLEQAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADES 123
Q + + ++ + +A V+ L+R Q ++++ + +L + A S
Sbjct: 1280 RARLQTEAGEYSRQLDEKDALVSQLSRSKQASTQQIEELKHQLEEETKAKNALAHALQSS 1339
Query: 124 ERGMKVIENRAMKDEE-KMELQEMQLKEAKHIAE-------DSDRKYEEVARKLVILEGE 175
++ + +++E K ELQ K +A+ D+ ++ EE+ L
Sbjct: 1340 RHDCDLLREQYEEEQEGKAELQRALSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQR 1399
Query: 176 LERSEERAEVAESRARQLEEELRTMDQALKSLMASEEEYST-------KEDKYEEEIKLL 228
L+ +EE E ++ LE+ + + ++ LM E + K+ +++ +
Sbjct: 1400 LQEAEEHVEAVNAKCASLEKTKQRLQNEVEDLMLDVERSNAACAALDKKQRNFDKVLSEW 1459
Query: 229 EEKLKEAETRAEFAER-------SVAKLEKTIDDLEETLASAKEENVEIHQTL 274
++K +E + E +++ + K++ ++ + L + + EN + Q +
Sbjct: 1460 KQKYEETQAELEASQKESRSLSTELFKVKNVYEESLDQLETLRRENKNLQQEI 1512
Score = 59.7 bits (143), Expect = 3e-09
Identities = 73/305 (23%), Positives = 134/305 (43%), Gaps = 44/305 (14%)
Query: 4 IKKKMQMLKLDKENAIDRAEQAEADK-KQAEDRCKQLEEEQQALQKKLKGTEDEVEKYS- 61
+KKKM+ + E ++ A + A+ + + L+E Q L L+G ED E+ +
Sbjct: 1617 VKKKMEGDLNEMEIQLNHANRLAAESLRNYRNTQGILKETQLHLDDALRGQEDLKEQLAI 1676
Query: 62 ---------ESVKEAQEKLEQAEKKATDAEADVASLNRRIQLVEEE---LDRAQERLATA 109
++E LEQ E+ AE ++ + R+QL+ + L +++L
Sbjct: 1677 VERRANLLQAEIEELWATLEQTERSRKIAEQELLDASERVQLLHTQNTSLINTKKKLEND 1736
Query: 110 LQKLE-EAEKAADES----ERGMKVIENRAMKDEEKMELQ------EMQLKEAKHIAEDS 158
+ +L+ E E+ ES E+ K I + AM EE + Q E K + +D
Sbjct: 1737 VSQLQSEVEEVIQESRNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNLEQTVKDL 1796
Query: 159 DRKYEEVARKLVILEGELERSEERAEVAESRARQLEEELRTMDQALKSLMASEEE----- 213
+ +E A +L + G+ + + A V E ++E E + +A+K L E
Sbjct: 1797 QHRLDE-AEQLALKGGKKQIQKLEARVRELEG-EVENEQKRNAEAVKGLRKHERRVKELT 1854
Query: 214 YSTKEDK-----YEEEIKLLEEKLKEAETRAEFAERS-------VAKLEKTIDDLEETLA 261
Y T+ED+ ++ + L+ K+K + +AE AE KL+ +++ EE
Sbjct: 1855 YQTEEDRKNVLRLQDLVDKLQAKVKSYKRQAEEAEEQSNANLSKFRKLQHELEEAEERAD 1914
Query: 262 SAKEE 266
A+ +
Sbjct: 1915 IAESQ 1919
Score = 59.3 bits (142), Expect = 4e-09
Identities = 62/319 (19%), Positives = 134/319 (42%), Gaps = 44/319 (13%)
Query: 2 DAIKKKMQMLKLDKENAIDRAEQAEADKKQAEDRCKQLEEEQQ----------------- 44
DAI++ ++ + K+ A R ++AE + +C LE+ +Q
Sbjct: 1381 DAIQRTEELEEAKKKLA-QRLQEAEEHVEAVNAKCASLEKTKQRLQNEVEDLMLDVERSN 1439
Query: 45 ----ALQKKLKGTEDEVEKYSESVKEAQEKLEQAEKKATDAEADVASLNR-------RIQ 93
AL KK + + + ++ + +E Q +LE ++K++ ++ + +++
Sbjct: 1440 AACAALDKKQRNFDKVLSEWKQKYEETQAELEASQKESRSLSTELFKVKNVYEESLDQLE 1499
Query: 94 LVEEELDRAQERLATALQKLEEAEKAADESERGMKVIENRAMKDEEKMELQEMQLKEAK- 152
+ E Q+ ++ +++ E K E E+ K +E + + +E E L+ +
Sbjct: 1500 TLRRENKNLQQEISDLTEQIAEGGKQIHELEKIKKQVEQEKCEIQAALEEAEASLEHEEG 1559
Query: 153 ---HIAEDSDRKYEEVARKLVILEGELER-SEERAEVAESRARQLEEELRTMDQALKSLM 208
I + ++ EV RK+ + E+++ V E+ L+ E+R+ + AL+
Sbjct: 1560 KILRIQLELNQVKSEVDRKIAEKDEEIDQLKRNHTRVVETMQSTLDAEIRSRNDALRVKK 1619
Query: 209 ASEEEYSTKEDKYEEEIKLLEEKLKEAETRAEFAERSVAKLEKTI---DDLEETLASAKE 265
E + + E + +L E L+ + + L+ + +DL+E LA +
Sbjct: 1620 KMEGDLNEMEIQLNHANRLAAESLRNYRNTQGILKETQLHLDDALRGQEDLKEQLAIVER 1679
Query: 266 -------ENVEIHQTLDQT 277
E E+ TL+QT
Sbjct: 1680 RANLLQAEIEELWATLEQT 1698
Score = 59.3 bits (142), Expect = 4e-09
Identities = 56/276 (20%), Positives = 119/276 (43%), Gaps = 28/276 (10%)
Query: 1 MDAIKKKMQMLKLDKENAIDRAEQAEADKKQAEDRCKQLEEEQQALQKKLKGTEDEVEKY 60
++ ++++ + L+ + + ++ + + E KQ+E+E+ +Q L+ E +E
Sbjct: 1498 LETLRRENKNLQQEISDLTEQIAEGGKQIHELEKIKKQVEQEKCEIQAALEEAEASLEHE 1557
Query: 61 SESVKEAQEKLEQAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAA 120
+ Q +L Q + + ++R+I +EE+D+ + ++ ++ A
Sbjct: 1558 EGKILRIQLELNQVK----------SEVDRKIAEKDEEIDQLKRNHTRVVETMQSTLDAE 1607
Query: 121 DESERGMKVIENRAMKDEEKME----LQEMQLKEAKHIAEDSDRKYEEVARKLVILEGEL 176
S N A++ ++KME E+QL A +A +S R Y +G L
Sbjct: 1608 IRS-------RNDALRVKKKMEGDLNEMEIQLNHANRLAAESLRNYRNT-------QGIL 1653
Query: 177 ERSEERAEVAESRARQLEEELRTMDQALKSLMASEEEYSTKEDKYEEEIKLLEEKLKEAE 236
+ ++ + A L+E+L +++ L A EE ++ E K+ E++L +A
Sbjct: 1654 KETQLHLDDALRGQEDLKEQLAIVERRANLLQAEIEELWATLEQTERSRKIAEQELLDAS 1713
Query: 237 TRAEFAERSVAKLEKTIDDLEETLASAKEENVEIHQ 272
R + L T LE ++ + E E+ Q
Sbjct: 1714 ERVQLLHTQNTSLINTKKKLENDVSQLQSEVEEVIQ 1749
Score = 58.9 bits (141), Expect = 5e-09
Identities = 60/290 (20%), Positives = 120/290 (41%), Gaps = 29/290 (10%)
Query: 1 MDAIKKKMQMLKLDKENAIDRAEQAEADKKQAEDRCKQLEEEQQALQKKLKGTEDEVEKY 60
+D ++ + ++ +K ++ + + ++ +L +E++ALQ+ + T D+++
Sbjct: 957 IDDLELTLAKVEKEKHATENKVKNLTEEMAGLDETIAKLSKEKKALQETHQQTLDDLQAE 1016
Query: 61 SESVKEAQEKLEQAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAA 120
+ V + + E++ D E + E+ + + L A +KLE K A
Sbjct: 1017 EDKVNILTKAKTKLEQQVDDLEGSL-----------EQEKKLRMDLERAKRKLEGDLKLA 1065
Query: 121 DESERGMKVIENRAMKDEEKMELQEMQLKEAKHIAEDSDRKYEEVARKLVILEGELERSE 180
ES M EN + +EK+E +E ++ ED ++ +K+ L+ +E
Sbjct: 1066 QESTMDM---ENDKQQLDEKLEKKEFEISNLISKIEDEQAVEIQLQKKIKELQARIEELG 1122
Query: 181 ERAEV-------AESRARQLEEELRTMDQALKSLMASEEEYSTKEDKYEEEIKLLEEKLK 233
E E AE + L EL + + L+ + K E E + L L+
Sbjct: 1123 EEIEAERASRAKAEKQRSDLSRELEEISERLEEAGGATSAQVELNKKREAEFQKLRRDLE 1182
Query: 234 EAETRAEFA--------ERSVAKLEKTIDDLEETLASAKEENVEIHQTLD 275
EA + E S+A+L + ID+L+ ++E E+ D
Sbjct: 1183 EATLQHEAMVAALRKKHADSMAELGEQIDNLQRVKQKLEKEKSELKMETD 1232
Score = 57.0 bits (136), Expect = 2e-08
Identities = 62/294 (21%), Positives = 134/294 (45%), Gaps = 46/294 (15%)
Query: 1 MDAIKKKMQMLKLDKENAIDRAEQAEADKKQAEDRCKQLEEE----QQALQKKLKGTEDE 56
++ IKK+++ K + + A+ E+AEA + E + +++ E + + +K+ ++E
Sbjct: 1529 LEKIKKQVEQEKCEIQAAL---EEAEASLEHEEGKILRIQLELNQVKSEVDRKIAEKDEE 1585
Query: 57 VEK----YSESVKEAQEKLEQAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQK 112
+++ ++ V+ Q L+ + DA + + +E +L+ A A +L+
Sbjct: 1586 IDQLKRNHTRVVETMQSTLDAEIRSRNDALRVKKKMEGDLNEMEIQLNHANRLAAESLRN 1645
Query: 113 -------LEEAEKAADESERGMK-------VIENRAMKDEEKMELQEMQLKEAKHIAEDS 158
L+E + D++ RG + ++E RA L + +++E E +
Sbjct: 1646 YRNTQGILKETQLHLDDALRGQEDLKEQLAIVERRA-------NLLQAEIEELWATLEQT 1698
Query: 159 DRKYEEVARKLVILEGELERSEERAEVAESRARQLEEELRTMDQALKSLMASEEEYSTKE 218
+R +RK I E EL + ER ++ ++ L + ++ + L + EE +
Sbjct: 1699 ER-----SRK--IAEQELLDASERVQLLHTQNTSLINTKKKLENDVSQLQSEVEEVIQES 1751
Query: 219 DKYEEEIK-------LLEEKLKEAETRAEFAERSVAKLEKTIDDLEETLASAKE 265
EE+ K ++ E+LK+ + + ER LE+T+ DL+ L A++
Sbjct: 1752 RNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNLEQTVKDLQHRLDEAEQ 1805
Score = 55.5 bits (132), Expect = 5e-08
Identities = 65/319 (20%), Positives = 121/319 (37%), Gaps = 63/319 (19%)
Query: 16 ENAIDRAEQAEADKKQAEDRCKQLEEEQQALQKKLKGTEDEVEKYSESVKEAQEKLEQAE 75
E ++D+ E + K + L E+ K++ E ++ + E Q LE+AE
Sbjct: 1492 EESLDQLETLRRENKNLQQEISDLTEQIAEGGKQIHELEKIKKQVEQEKCEIQAALEEAE 1551
Query: 76 KKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERG-MKVIE--- 131
E + + + V+ E+DR K+ E ++ D+ +R +V+E
Sbjct: 1552 ASLEHEEGKILRIQLELNQVKSEVDR----------KIAEKDEEIDQLKRNHTRVVETMQ 1601
Query: 132 ----------NRAMKDEEKME----LQEMQLKEAKHIAEDSDRKYEE------------- 164
N A++ ++KME E+QL A +A +S R Y
Sbjct: 1602 STLDAEIRSRNDALRVKKKMEGDLNEMEIQLNHANRLAAESLRNYRNTQGILKETQLHLD 1661
Query: 165 ---------------VARKLVILEGELERSEERAEVAESRARQLEEELRTMDQALKSLMA 209
V R+ +L+ E+E E E + E+EL + ++ L
Sbjct: 1662 DALRGQEDLKEQLAIVERRANLLQAEIEELWATLEQTERSRKIAEQELLDASERVQLLHT 1721
Query: 210 SEEEYSTKEDKYEEEIKLLEEKLKEAETRAEFAERSVAKLEKTIDDLEETLASAKEENVE 269
+ K E ++ L+ +++E + AE K + E L KE++
Sbjct: 1722 QNTSLINTKKKLENDVSQLQSEVEEVIQESRNAEEKAKKAITDAAMMAEEL--KKEQDTS 1779
Query: 270 IH-----QTLDQTLLELNN 283
H + L+QT+ +L +
Sbjct: 1780 AHLERMKKNLEQTVKDLQH 1798
Score = 54.3 bits (129), Expect = 1e-07
Identities = 60/258 (23%), Positives = 125/258 (48%), Gaps = 22/258 (8%)
Query: 25 AEADKKQAEDRCKQLEEEQQALQKKLKGTEDEVEKYSESVKEAQEKLEQAEKKATDAEAD 84
++A+ + A+ R K E A+Q+ + E+ +K ++ ++EA+E +E K A
Sbjct: 1365 SKANSEVAQWRTKY---ETDAIQRT-EELEEAKKKLAQRLQEAEEHVEAVNAKC----AS 1416
Query: 85 VASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADE--SERGMKVIENRAMKDEEKME 142
+ +R+Q E+L ER A L++ ++ D+ SE K E +A + + E
Sbjct: 1417 LEKTKQRLQNEVEDLMLDVERSNAACAALDKKQRNFDKVLSEWKQKYEETQAELEASQKE 1476
Query: 143 LQEM--QLKEAKHIAEDSDRKYEEVARKLVILEGELERSEERAEVAESRARQLEEELRTM 200
+ + +L + K++ E+S + E + R+ L+ E+ E+ + +LE+ + +
Sbjct: 1477 SRSLSTELFKVKNVYEESLDQLETLRRENKNLQQEISDLTEQIAEGGKQIHELEKIKKQV 1536
Query: 201 DQALKSLMASEEEYSTKEDKYEEEIKLLEEKLKEAETRAEFAERSVAKLEKTIDDLEETL 260
+Q + A+ EE + EE K+L +L+ + ++E +R +A+ ++ ID L
Sbjct: 1537 EQEKCEIQAALEEAEASLE--HEEGKILRIQLELNQVKSE-VDRKIAEKDEEIDQL---- 1589
Query: 261 ASAKEENVEIHQTLDQTL 278
K + + +T+ TL
Sbjct: 1590 ---KRNHTRVVETMQSTL 1604
Score = 47.4 bits (111), Expect = 1e-05
Identities = 38/156 (24%), Positives = 73/156 (46%), Gaps = 12/156 (7%)
Query: 1 MDAIKKKMQMLKLDKENAIDRAEQA--EADKKQA---EDRCKQLEEEQQALQKKLKGTED 55
++ +KK ++ D ++ +D AEQ + KKQ E R ++LE E + QK+
Sbjct: 1782 LERMKKNLEQTVKDLQHRLDEAEQLALKGGKKQIQKLEARVRELEGEVENEQKRNAEAVK 1841
Query: 56 EVEKYSESVKEAQEKLEQAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQK--- 112
+ K+ VKE + E+ K + V L +++ + + + A+E+ L K
Sbjct: 1842 GLRKHERRVKELTYQTEEDRKNVLRLQDLVDKLQAKVKSYKRQAEEAEEQSNANLSKFRK 1901
Query: 113 ----LEEAEKAADESERGMKVIENRAMKDEEKMELQ 144
LEEAE+ AD +E + + ++ + K+ +
Sbjct: 1902 LQHELEEAEERADIAESQVNKLRVKSREVHTKISAE 1937
Score = 47.0 bits (110), Expect = 2e-05
Identities = 47/259 (18%), Positives = 103/259 (39%), Gaps = 31/259 (11%)
Query: 3 AIKKKMQMLKLDKENAIDRAEQAEADKKQAEDRCKQLEEEQQALQKKLKGTEDEVEKYSE 62
A++KK + ID ++ + ++ + K ++ + + + + +EK
Sbjct: 1194 ALRKKHADSMAELGEQIDNLQRVKQKLEKEKSELKMETDDLSSNAEAISKAKGNLEKMCR 1253
Query: 63 SVKEAQEKLEQAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADE 122
S+++ +L+ E++ D+ + R+Q E R + + +L +++A+ +
Sbjct: 1254 SLEDQVSELKTKEEEQQRLINDLTAQRARLQTEAGEYSRQLDEKDALVSQLSRSKQASTQ 1313
Query: 123 SERGMKVIENRAMKDEEKMELQEMQLKEAKHIAEDSDRKYEEVARKLVILEGELERSEER 182
Q++E KH E+ + +A L + + E+
Sbjct: 1314 ------------------------QIEELKHQLEEETKAKNALAHALQSSRHDCDLLREQ 1349
Query: 183 AEVAESRARQLEEELRTMDQALKSLMASEEEYST----KEDKYEEEIKLLEEKLKEAETR 238
E + +L+ R + +A + +Y T + ++ EE K L ++L+EAE
Sbjct: 1350 YEEEQEGKAELQ---RALSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQEAEEH 1406
Query: 239 AEFAERSVAKLEKTIDDLE 257
E A LEKT L+
Sbjct: 1407 VEAVNAKCASLEKTKQRLQ 1425
>gi|31982906 cingulin-like 1 [Homo sapiens]
Length = 1302
Score = 80.5 bits (197), Expect = 2e-15
Identities = 64/313 (20%), Positives = 139/313 (44%), Gaps = 29/313 (9%)
Query: 1 MDAIKKKMQMLKLDKENAIDRAEQAEADKKQAEDRCKQLEEEQQALQKK----------- 49
+ A+++ ++ + E R+ +E D+ E R K L+EE + LQ +
Sbjct: 789 LQALRESVEEATKNVEVLASRSNTSEQDQAGTEMRVKLLQEENEKLQGRSEELERRVAQL 848
Query: 50 ------LKGTE----DEVEKYSESVKEAQEKLEQAEKKATDAEADVASLNRRIQLVEEEL 99
LKG E + ++KY +++ +E L A K+ +A + +L ++ + L
Sbjct: 849 QRQIEDLKGDEAKAKETLKKYEGEIRQLEEALVHARKEEKEAVSARRALENELEAAQGNL 908
Query: 100 DRAQERLATALQKLEEAEKAADESERGMKVIENRAM---KDEEKMELQEMQLKEAK---- 152
+ + +KL+E + ++ R +EN K EK++ + + EA
Sbjct: 909 SQTTQEQKQLSEKLKEESEQKEQLRRLKNEMENERWHLGKTIEKLQKEMADIVEASRTST 968
Query: 153 -HIAEDSDRKYEEVARKLVILEGELERSEERAEVAESRARQLEEELRTMDQALKSLMASE 211
+ D E+ R+L ++ +L+ AE + A ++++E+R M++ L+ ++
Sbjct: 969 LELQNQLDEYKEKNRRELAEMQRQLKEKTLEAEKSRLTAMKMQDEMRLMEEELRDYQRAQ 1028
Query: 212 EEYSTKEDKYEEEIKLLEEKLKEAETRAEFAERSVAKLEKTIDDLEETLASAKEENVEIH 271
+E TK E+ +K LE +L+ + R V ++E + LE L + + +
Sbjct: 1029 DEALTKRQLLEQTLKDLEYELEAKSHLKDDRSRLVKQMEDKVSQLEMELEEERNNSDLLS 1088
Query: 272 QTLDQTLLELNNL 284
+ + ++ ++ L
Sbjct: 1089 ERISRSREQMEQL 1101
Score = 71.2 bits (173), Expect = 9e-13
Identities = 61/268 (22%), Positives = 127/268 (47%), Gaps = 26/268 (9%)
Query: 30 KQAEDRCKQLEEEQQALQKKLKGTEDEVEKYSESVKEAQEKLEQAEKKATDAEADVASLN 89
K++EDR E+ AL ++L + +++ + +E ++ L + E++ T + +L
Sbjct: 718 KRSEDR------EKGALIEELLQAKQDLQDLLIAKEEQEDLLRKRERELTALKG---ALK 768
Query: 90 RRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIENRAMKDEEKMELQEMQLK 149
+ ++E+D+ +E+ LQ L E+ +E+ + ++V+ +R+ E+ EM++K
Sbjct: 769 EEVSSHDQEMDKLKEQYDAELQALRES---VEEATKNVEVLASRSNTSEQDQAGTEMRVK 825
Query: 150 EAKHIAEDSDRKYEEVARKLVILEGELERSEERAEVAESRARQLEEELRTMDQALKSLMA 209
+ E + EE+ R++ L+ ++E + A+ ++ E E+R +++AL
Sbjct: 826 LLQEENEKLQGRSEELERRVAQLQRQIEDLKGDEAKAKETLKKYEGEIRQLEEALVHARK 885
Query: 210 SEEEYSTKEDKYEEEI--------------KLLEEKLKEAETRAEFAERSVAKLEKTIDD 255
E+E + E E+ K L EKLKE + E R ++E
Sbjct: 886 EEKEAVSARRALENELEAAQGNLSQTTQEQKQLSEKLKEESEQKEQLRRLKNEMENERWH 945
Query: 256 LEETLASAKEENVEIHQTLDQTLLELNN 283
L +T+ ++E +I + + LEL N
Sbjct: 946 LGKTIEKLQKEMADIVEASRTSTLELQN 973
Score = 69.7 bits (169), Expect = 3e-12
Identities = 59/261 (22%), Positives = 121/261 (46%), Gaps = 19/261 (7%)
Query: 25 AEADKKQAEDRCKQLEEEQQALQKKLKGTEDEVEKYSESVKEAQEKLEQAEKKATDAEAD 84
A ++K+A + LE E +A Q L T E ++ SE +KE E+ EQ + + E +
Sbjct: 883 ARKEEKEAVSARRALENELEAAQGNLSQTTQEQKQLSEKLKEESEQKEQLRRLKNEMENE 942
Query: 85 VASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIENRAMKDEEKMELQ 144
L + I+ +++E+ E T+ +L + DE K++ + EL
Sbjct: 943 RWHLGKTIEKLQKEMADIVEASRTSTLEL---QNQLDE------------YKEKNRRELA 987
Query: 145 EM--QLKEAKHIAEDSDRKYEEVARKLVILEGELERSEERAEVAESRARQLEEELRTMDQ 202
EM QLKE AE S ++ ++ ++E EL + + A ++ + LE+ L+ ++
Sbjct: 988 EMQRQLKEKTLEAEKSRLTAMKMQDEMRLMEEELRDYQRAQDEALTKRQLLEQTLKDLEY 1047
Query: 203 ALKSLMASEEEYSTKEDKYEEEIKLLEEKLKEAETRAEFAERSVAKLEKTIDDLEETLAS 262
L++ +++ S + E+++ LE +L+E ++ +++ + ++ L L
Sbjct: 1048 ELEAKSHLKDDRSRLVKQMEDKVSQLEMELEEERNNSDLLSERISRSREQMEQLRNELLQ 1107
Query: 263 AKEENVEIHQTLDQTLLELNN 283
+ ++ D+ LE N
Sbjct: 1108 ERAARQDLE--CDKISLERQN 1126
Score = 67.4 bits (163), Expect = 1e-11
Identities = 76/299 (25%), Positives = 138/299 (46%), Gaps = 41/299 (13%)
Query: 2 DAIKKKMQMLKLDKENAIDRAEQAEADKKQAEDRCKQLEEEQQALQKKLKGTEDEVE--- 58
DA K+K+ ++ + RA + QA C E + L++K K T + E
Sbjct: 572 DATKRKVNLVFEKIQTLKSRAAGSAQGNNQA---CNSTSEVKDLLEQKSKLTIEVAELQR 628
Query: 59 ------KYSESVKEAQEK----LEQAEKKATDAEADVASLNRRIQLVEEELDRAQERLAT 108
K +++KE +E+ LE+ + + + ++L +R++ E EL + E L
Sbjct: 629 QLQLEVKNQQNIKEERERMRANLEELRSQHNEKVEENSTLQQRLEESEGELRKNLEELFQ 688
Query: 109 ALQKLEEAEKAADE-----SERGMKVIENRAMKDEEKMELQE--MQLKE-------AKHI 154
+ E+ + + SE ++ + +D EK L E +Q K+ AK
Sbjct: 689 VKMEREQHQTEIRDLQDQLSEMHDELDSAKRSEDREKGALIEELLQAKQDLQDLLIAKEE 748
Query: 155 AEDSDRKYEEVARKLVILEGELE-----RSEERAEVAESRARQLEEELRTMDQALKSLMA 209
ED RK E R+L L+G L+ +E ++ E +L+ ++++A K++
Sbjct: 749 QEDLLRKRE---RELTALKGALKEEVSSHDQEMDKLKEQYDAELQALRESVEEATKNVEV 805
Query: 210 SEEEYSTKEDKY---EEEIKLLEEKLKEAETRAEFAERSVAKLEKTIDDLEETLASAKE 265
+T E E +KLL+E+ ++ + R+E ER VA+L++ I+DL+ A AKE
Sbjct: 806 LASRSNTSEQDQAGTEMRVKLLQEENEKLQGRSEELERRVAQLQRQIEDLKGDEAKAKE 864
Score = 61.6 bits (148), Expect = 7e-10
Identities = 57/259 (22%), Positives = 116/259 (44%), Gaps = 22/259 (8%)
Query: 1 MDAIKKKMQMLKLDKENAIDRAEQAEADKKQAEDRCKQLEEEQQALQKKLKGTEDEVEKY 60
++A K ++ +K+ E + E + + Q E K+ Q L++ LK E E+E
Sbjct: 998 LEAEKSRLTAMKMQDEMRLMEEELRDYQRAQDEALTKR-----QLLEQTLKDLEYELEAK 1052
Query: 61 SESVKEAQEKLEQAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAA 120
S + ++Q E K + E ++ L+ E + R++E++ +L + A
Sbjct: 1053 SHLKDDRSRLVKQMEDKVSQLEMELEEERNNSDLLSERISRSREQMEQLRNELLQERAAR 1112
Query: 121 DESERGMKVIENRAMKDEEKMELQEMQLKEAKHIAEDSDRKYEEVARKLVILEGELERSE 180
+ E D+ +E Q LK E S R +E +V +E + E
Sbjct: 1113 QDLEC-----------DKISLERQNKDLKSRIIHLEGSYRSSKEGL--VVQMEARIAELE 1159
Query: 181 ERAEVAESRARQLEEELRTMDQALKSL-MASEEEYSTKEDKYEE---EIKLLEEKLKEAE 236
+R E E L+ R +++ +K L M ++E+ + D+ ++ +K ++ +++EAE
Sbjct: 1160 DRLESEERDRANLQLSNRRLERKVKELVMQVDDEHLSLTDQKDQLSLRLKAMKRQVEEAE 1219
Query: 237 TRAEFAERSVAKLEKTIDD 255
+ E S KL++ +++
Sbjct: 1220 EEIDRLESSKKKLQRELEE 1238
Score = 61.2 bits (147), Expect = 1e-09
Identities = 64/295 (21%), Positives = 127/295 (43%), Gaps = 36/295 (12%)
Query: 12 KLDKENAIDRAEQAEADKKQAEDRCKQLEEEQQAL-----QKKLKGTEDEVEKYSESVKE 66
+LD+ +R E AE ++ E K LE E+ L Q +++ E+E+ Y + E
Sbjct: 974 QLDEYKEKNRRELAEMQRQLKE---KTLEAEKSRLTAMKMQDEMRLMEEELRDYQRAQDE 1030
Query: 67 AQEKLEQAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQ-KLEEAEKAADESER 125
A K + E+ D E ++ + + L + RL ++ K+ + E +E
Sbjct: 1031 ALTKRQLLEQTLKDLEYELEA--------KSHLKDDRSRLVKQMEDKVSQLEMELEEERN 1082
Query: 126 GMKVIENRAMKDEEKMELQEMQLKEAKHIAEDSD-------RKYEEVARKLVILEGELER 178
++ R + E+ME +L + + +D + R+ +++ +++ LEG
Sbjct: 1083 NSDLLSERISRSREQMEQLRNELLQERAARQDLECDKISLERQNKDLKSRIIHLEGSYRS 1142
Query: 179 SEERAEVA-ESRARQLEEELRTMDQALKSLMASEEEYSTKEDKY-----EEEIKLLEEK- 231
S+E V E+R +LE+ L + ++ +L S K + +E + L ++K
Sbjct: 1143 SKEGLVVQMEARIAELEDRLESEERDRANLQLSNRRLERKVKELVMQVDDEHLSLTDQKD 1202
Query: 232 -----LKEAETRAEFAERSVAKLEKTIDDLEETLASAKEENVEIHQTLDQTLLEL 281
LK + + E AE + +LE + L+ L + N + L+ +L
Sbjct: 1203 QLSLRLKAMKRQVEEAEEEIDRLESSKKKLQRELEEQMDMNEHLQGQLNSMKKDL 1257
Score = 60.8 bits (146), Expect = 1e-09
Identities = 61/289 (21%), Positives = 136/289 (47%), Gaps = 46/289 (15%)
Query: 4 IKKKMQMLKLDKENAIDRAEQAEADKKQAEDRCKQLEEEQQALQKKLKGTEDEVEKYSES 63
+++++Q+ +++N + E+ A+ ++ + + EE LQ++L+ +E E+ K E
Sbjct: 626 LQRQLQLEVKNQQNIKEERERMRANLEELRSQHNEKVEENSTLQQRLEESEGELRKNLEE 685
Query: 64 VKEAQEKLEQAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADES 123
+ + + + EQ + + D + ++ ++ +ELD A K +++
Sbjct: 686 LFQVKMEREQHQTEIRDLQDQLSEMH-------DELDSA---------------KRSEDR 723
Query: 124 ERGMKVIENRAMKDEEKMELQEMQLKEAKHIAEDSDRKYEEVARKLVILEGELERS---- 179
E+G + E + K +LQ++ + AK ED RK E R+L L+G L+
Sbjct: 724 EKGALIEELL----QAKQDLQDLLI--AKEEQEDLLRKRE---RELTALKGALKEEVSSH 774
Query: 180 -EERAEVAESRARQLEEELRTMDQALKSLMASEEEYSTKEDKY---EEEIKLLEEKLKEA 235
+E ++ E +L+ ++++A K++ +T E E +KLL+E+ ++
Sbjct: 775 DQEMDKLKEQYDAELQALRESVEEATKNVEVLASRSNTSEQDQAGTEMRVKLLQEENEKL 834
Query: 236 ETRAEFAERSVAKLEKTIDDLEETLASAKEENVEIHQTLDQTLLELNNL 284
+ R+E +LE+ + L+ + K + + +TL + E+ L
Sbjct: 835 QGRSE-------ELERRVAQLQRQIEDLKGDEAKAKETLKKYEGEIRQL 876
Score = 45.4 bits (106), Expect = 6e-05
Identities = 47/215 (21%), Positives = 93/215 (43%), Gaps = 28/215 (13%)
Query: 30 KQAEDRCKQLEEEQQALQKKLKGTEDEVEKYSESVKEAQEKLEQAEKKATDAEADVASLN 89
KQ ED+ QLE E + + + + + E +++ + +L Q D E D SL
Sbjct: 1064 KQMEDKVSQLEMELEEERNNSDLLSERISRSREQMEQLRNELLQERAARQDLECDKISLE 1123
Query: 90 R-------RIQLVEEELDRAQERLATALQ-KLEEAEKA--ADESERGMKVIENRAMK--- 136
R RI +E ++E L ++ ++ E E ++E +R + NR ++
Sbjct: 1124 RQNKDLKSRIIHLEGSYRSSKEGLVVQMEARIAELEDRLESEERDRANLQLSNRRLERKV 1183
Query: 137 -------DEEKMELQE------MQLKEAKHIAEDSDRKYEEVARKLVILEGELERSEERA 183
D+E + L + ++LK K E+++ + + + L+ ELE +
Sbjct: 1184 KELVMQVDDEHLSLTDQKDQLSLRLKAMKRQVEEAEEEIDRLESSKKKLQRELEEQMDMN 1243
Query: 184 EVAESRARQLEEELRTMDQALKSL--MASEEEYST 216
E + + ++++LR K L M +++ ST
Sbjct: 1244 EHLQGQLNSMKKDLRLKKLPSKVLDDMDDDDDLST 1278
Score = 35.4 bits (80), Expect = 0.057
Identities = 48/245 (19%), Positives = 91/245 (37%), Gaps = 16/245 (6%)
Query: 47 QKKLKGTEDEVEKYSESVKEAQEKLEQAEKKATDAEADVASLNRRIQLVEEELDRAQERL 106
Q + G E E ES L KK + + A+L + + D +++
Sbjct: 463 QPNIDGKVLETEGSQESTVIRAPSLGAQSKKEEEVKTATATLMLQNRATATSPDSGAKKI 522
Query: 107 ATALQKLEEAEKAADESERGMKVIENRAMKDEEKMELQEMQLKEAKHIAEDSD-RKYEEV 165
+ +A + +G + + + ++ K L LKE +D+ RK V
Sbjct: 523 SVKTFPSASNTQATPDLLKGQQELTQQTNEETAKQILYNY-LKEGSTDNDDATKRKVNLV 581
Query: 166 ARKLVILEGELERS-----------EERAEVAESRAR---QLEEELRTMDQALKSLMASE 211
K+ L+ S E ++ E +++ ++ E R + +K+ +
Sbjct: 582 FEKIQTLKSRAAGSAQGNNQACNSTSEVKDLLEQKSKLTIEVAELQRQLQLEVKNQQNIK 641
Query: 212 EEYSTKEDKYEEEIKLLEEKLKEAETRAEFAERSVAKLEKTIDDLEETLASAKEENVEIH 271
EE EE EK++E T + E S +L K +++L + ++ EI
Sbjct: 642 EERERMRANLEELRSQHNEKVEENSTLQQRLEESEGELRKNLEELFQVKMEREQHQTEIR 701
Query: 272 QTLDQ 276
DQ
Sbjct: 702 DLQDQ 706
Score = 33.9 bits (76), Expect = 0.17
Identities = 59/263 (22%), Positives = 106/263 (40%), Gaps = 58/263 (22%)
Query: 44 QALQKKLKGTEDEVEKYSESVKEAQEKLEQAEKKATDAEADVASLNRRIQLVEEELDRAQ 103
QA LKG ++ ++ +E A++ L K+ + D R++ LV E++ +
Sbjct: 534 QATPDLLKGQQELTQQTNEET--AKQILYNYLKEGSTDNDDATK--RKVNLVFEKIQTLK 589
Query: 104 ERLATALQKLEEAEKAADESERGMKVIENRAMKDEEKMELQEMQLKEAKHIAEDSDRKYE 163
R A + Q +A + E K + E +
Sbjct: 590 SRAAGSAQGNNQACNSTSE----------------------------VKDLLEQKSKLTI 621
Query: 164 EVARKLVILEGEL--------ERSEERAEVAESRARQLE--EELRTMDQALKSLMAS--- 210
EVA L+ E+ ER RA + E R++ E EE T+ Q L+
Sbjct: 622 EVAELQRQLQLEVKNQQNIKEERERMRANLEELRSQHNEKVEENSTLQQRLEESEGELRK 681
Query: 211 --EEEYSTK--EDKYEEEIKLLEEKLKEAETRAEFAERS--------VAKLEKTIDDLEE 258
EE + K ++++ EI+ L+++L E + A+RS + +L + DL++
Sbjct: 682 NLEELFQVKMEREQHQTEIRDLQDQLSEMHDELDSAKRSEDREKGALIEELLQAKQDLQD 741
Query: 259 TLASAKEENVEIHQTLDQTLLEL 281
L AKEE ++ + ++ L L
Sbjct: 742 LLI-AKEEQEDLLRKRERELTAL 763
Score = 30.0 bits (66), Expect = 2.4
Identities = 14/71 (19%), Positives = 37/71 (52%)
Query: 24 QAEADKKQAEDRCKQLEEEQQALQKKLKGTEDEVEKYSESVKEAQEKLEQAEKKATDAEA 83
Q + + D+ QL +A++++++ E+E+++ S K+ Q +LE+ +
Sbjct: 1189 QVDDEHLSLTDQKDQLSLRLKAMKRQVEEAEEEIDRLESSKKKLQRELEEQMDMNEHLQG 1248
Query: 84 DVASLNRRIQL 94
+ S+ + ++L
Sbjct: 1249 QLNSMKKDLRL 1259
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.301 0.119 0.285
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 8,541,776
Number of Sequences: 37866
Number of extensions: 420044
Number of successful extensions: 24335
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 1062
Number of HSP's successfully gapped in prelim test: 1153
Number of HSP's that attempted gapping in prelim test: 4322
Number of HSP's gapped (non-prelim): 9360
length of query: 284
length of database: 18,247,518
effective HSP length: 101
effective length of query: 183
effective length of database: 14,423,052
effective search space: 2639418516
effective search space used: 2639418516
T: 11
A: 40
X1: 17 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 43 (21.7 bits)
S2: 61 (28.1 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.