Home |
Table of Contents |
Search text |
Search genes |
Search sequences |
Purchase |
FAQ |
Blog |
Help
Search of human proteins with 47132620
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|47132620 keratin 2 [Homo sapiens]
(639 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|47132620 keratin 2 [Homo sapiens] 1270 0.0
gi|119395750 keratin 1 [Homo sapiens] 763 0.0
gi|109148552 keratin 3 [Homo sapiens] 704 0.0
gi|153791670 keratin 76 [Homo sapiens] 702 0.0
gi|119395754 keratin 5 [Homo sapiens] 647 0.0
gi|194018511 keratin 77 [Homo sapiens] 633 0.0
gi|119703753 keratin 6B [Homo sapiens] 630 0.0
gi|5031839 keratin 6A [Homo sapiens] 629 e-180
gi|155969697 keratin 6C [Homo sapiens] 628 e-180
gi|109255249 keratin 4 [Homo sapiens] 579 e-165
gi|153791158 keratin 75 [Homo sapiens] 575 e-164
gi|32567786 keratin 6L [Homo sapiens] 555 e-158
gi|28173564 keratin 73 [Homo sapiens] 546 e-155
gi|15618995 keratin 71 [Homo sapiens] 536 e-152
gi|148612803 keratin 6 irs4 [Homo sapiens] 529 e-150
gi|28372503 keratin 72 isoform 1 [Homo sapiens] 525 e-149
gi|226246663 keratin 72 isoform 1 [Homo sapiens] 525 e-149
gi|4504919 keratin 8 [Homo sapiens] 454 e-127
gi|15431316 keratin, hair, basic, 4 [Homo sapiens] 444 e-124
gi|89357932 keratin 5b [Homo sapiens] 433 e-121
gi|67782365 keratin 7 [Homo sapiens] 430 e-120
gi|226246665 keratin 72 isoform 2 [Homo sapiens] 410 e-114
gi|4504935 keratin 85 [Homo sapiens] 393 e-109
gi|27477127 keratin 82 [Homo sapiens] 389 e-108
gi|169790853 keratin, hair, basic, 1 [Homo sapiens] 388 e-108
gi|239755818 PREDICTED: hypothetical protein isoform 2 [Homo sap... 381 e-106
gi|239755816 PREDICTED: hypothetical protein isoform 1 [Homo sap... 381 e-106
gi|239755814 PREDICTED: hypothetical protein isoform 3 [Homo sap... 381 e-106
gi|14318422 keratin 86 [Homo sapiens] 381 e-106
gi|169790841 keratin 83 [Homo sapiens] 377 e-104
>gi|47132620 keratin 2 [Homo sapiens]
Length = 639
Score = 1270 bits (3286), Expect = 0.0
Identities = 639/639 (100%), Positives = 639/639 (100%)
Query: 1 MSCQISCKSRGRGGGGGGFRGFSSGSAVVSGGSRRSTSSFSCLSRHGGGGGGFGGGGFGS 60
MSCQISCKSRGRGGGGGGFRGFSSGSAVVSGGSRRSTSSFSCLSRHGGGGGGFGGGGFGS
Sbjct: 1 MSCQISCKSRGRGGGGGGFRGFSSGSAVVSGGSRRSTSSFSCLSRHGGGGGGFGGGGFGS 60
Query: 61 RSLVGLGGTKSISISVAGGGGGFGAAGGFGGRGGGFGGGSSFGGGSGFSGGGFGGGGFGG 120
RSLVGLGGTKSISISVAGGGGGFGAAGGFGGRGGGFGGGSSFGGGSGFSGGGFGGGGFGG
Sbjct: 61 RSLVGLGGTKSISISVAGGGGGFGAAGGFGGRGGGFGGGSSFGGGSGFSGGGFGGGGFGG 120
Query: 121 GRFGGFGGPGGVGGLGGPGGFGPGGYPGGIHEVSVNQSLLQPLNVKVDPEIQNVKAQERE 180
GRFGGFGGPGGVGGLGGPGGFGPGGYPGGIHEVSVNQSLLQPLNVKVDPEIQNVKAQERE
Sbjct: 121 GRFGGFGGPGGVGGLGGPGGFGPGGYPGGIHEVSVNQSLLQPLNVKVDPEIQNVKAQERE 180
Query: 181 QIKTLNNKFASFIDKVRFLEQQNQVLQTKWELLQQMNVGTRPINLEPIFQGYIDSLKRYL 240
QIKTLNNKFASFIDKVRFLEQQNQVLQTKWELLQQMNVGTRPINLEPIFQGYIDSLKRYL
Sbjct: 181 QIKTLNNKFASFIDKVRFLEQQNQVLQTKWELLQQMNVGTRPINLEPIFQGYIDSLKRYL 240
Query: 241 DGLTAERTSQNSELNNMQDLVEDYKKKYEDEINKRTAAENDFVTLKKDVDNAYMIKVELQ 300
DGLTAERTSQNSELNNMQDLVEDYKKKYEDEINKRTAAENDFVTLKKDVDNAYMIKVELQ
Sbjct: 241 DGLTAERTSQNSELNNMQDLVEDYKKKYEDEINKRTAAENDFVTLKKDVDNAYMIKVELQ 300
Query: 301 SKVDLLNQEIEFLKVLYDAEISQIHQSVTDTNVILSMDNSRNLDLDSIIAEVKAQYEEIA 360
SKVDLLNQEIEFLKVLYDAEISQIHQSVTDTNVILSMDNSRNLDLDSIIAEVKAQYEEIA
Sbjct: 301 SKVDLLNQEIEFLKVLYDAEISQIHQSVTDTNVILSMDNSRNLDLDSIIAEVKAQYEEIA 360
Query: 361 QRSKEEAEALYHSKYEELQVTVGRHGDSLKEIKIEISELNRVIQRLQGEIAHVKKQCKNV 420
QRSKEEAEALYHSKYEELQVTVGRHGDSLKEIKIEISELNRVIQRLQGEIAHVKKQCKNV
Sbjct: 361 QRSKEEAEALYHSKYEELQVTVGRHGDSLKEIKIEISELNRVIQRLQGEIAHVKKQCKNV 420
Query: 421 QDAIADAEQRGEHALKDARNKLNDLEEALQQAKEDLARLLRDYQELMNVKLALDVEIATY 480
QDAIADAEQRGEHALKDARNKLNDLEEALQQAKEDLARLLRDYQELMNVKLALDVEIATY
Sbjct: 421 QDAIADAEQRGEHALKDARNKLNDLEEALQQAKEDLARLLRDYQELMNVKLALDVEIATY 480
Query: 481 RKLLEGEECRMSGDLSSNVTVSVTSSTISSNVASKAAFGGSGGRGSSSGGGYSSGSSSYG 540
RKLLEGEECRMSGDLSSNVTVSVTSSTISSNVASKAAFGGSGGRGSSSGGGYSSGSSSYG
Sbjct: 481 RKLLEGEECRMSGDLSSNVTVSVTSSTISSNVASKAAFGGSGGRGSSSGGGYSSGSSSYG 540
Query: 541 SGGRQSGSRGGSGGGGSISGGGYGSGGGSGGRYGSGGGSKGGSISGGGYGSGGGKHSSGG 600
SGGRQSGSRGGSGGGGSISGGGYGSGGGSGGRYGSGGGSKGGSISGGGYGSGGGKHSSGG
Sbjct: 541 SGGRQSGSRGGSGGGGSISGGGYGSGGGSGGRYGSGGGSKGGSISGGGYGSGGGKHSSGG 600
Query: 601 GSRGGSSSGGGYGSGGGGSSSVKGSSGEAFGSSVTFSFR 639
GSRGGSSSGGGYGSGGGGSSSVKGSSGEAFGSSVTFSFR
Sbjct: 601 GSRGGSSSGGGYGSGGGGSSSVKGSSGEAFGSSVTFSFR 639
>gi|119395750 keratin 1 [Homo sapiens]
Length = 644
Score = 763 bits (1970), Expect = 0.0
Identities = 424/651 (65%), Positives = 491/651 (75%), Gaps = 46/651 (7%)
Query: 1 MSCQISCKSRGRGGGGGGFRGFSSGSAVVSGGSRRSTSSFSC--------LSRHGGGGGG 52
MS Q S +S R GGG FSSGSA + RR+TSS + S GGGGG
Sbjct: 1 MSRQFSSRSGYRSGGG-----FSSGSAGIINYQRRTTSSSTRRSGGGGGRFSSCGGGGGS 55
Query: 53 FG-GGGFGSRSLVGLGGTKSISISVAGGGG-GFGAAGGFGGRGGGFGGGSSFGGGSGFSG 110
FG GGGFGSRSLV LGG+KSISISVA GGG G G GG+GG GGFGGG GF G
Sbjct: 56 FGAGGGFGSRSLVNLGGSKSISISVARGGGRGSGFGGGYGG--GGFGGG-------GFGG 106
Query: 111 GGFGGGGFGGGRFGGFG------GPGGVGGLGGPGGFGPGGYPGGIHEVSVNQSLLQPLN 164
GGFGGGG GGG FGGFG G GG GG G GG+GP PGGI EV++NQSLLQPLN
Sbjct: 107 GGFGGGGIGGGGFGGFGSGGGGFGGGGFGGGGYGGGYGPVCPPGGIQEVTINQSLLQPLN 166
Query: 165 VKVDPEIQNVKAQEREQIKTLNNKFASFIDKVRFLEQQNQVLQTKWELLQQMNVGTRPIN 224
V++DPEIQ VK++EREQIK+LNN+FASFIDKVRFLEQQNQVLQTKWELLQQ++ TR N
Sbjct: 167 VEIDPEIQKVKSREREQIKSLNNQFASFIDKVRFLEQQNQVLQTKWELLQQVDTSTRTHN 226
Query: 225 LEPIFQGYIDSLKRYLDGLTAERTSQNSELNNMQDLVEDYKKKYEDEINKRTAAENDFVT 284
LEP F+ +I++L+R +D L ++++ +SEL NMQD+VEDY+ KYEDEINKRT AEN+FVT
Sbjct: 227 LEPYFESFINNLRRRVDQLKSDQSRLDSELKNMQDMVEDYRNKYEDEINKRTNAENEFVT 286
Query: 285 LKKDVDNAYMIKVELQSKVDLLNQEIEFLKVLYDAEISQIHQSVTDTNVILSMDNSRNLD 344
+KKDVD AYM KV+LQ+K+D L QEI+FL LY AE+SQ+ +++TNVILSMDN+R+LD
Sbjct: 287 IKKDVDGAYMTKVDLQAKLDNLQQEIDFLTALYQAELSQMQTQISETNVILSMDNNRSLD 346
Query: 345 LDSIIAEVKAQYEEIAQRSKEEAEALYHSKYEELQVTVGRHGDSLKEIKIEISELNRVIQ 404
LDSIIAEVKAQYE+IAQ+SK EAE+LY SKYEELQ+T GRHGDS++ KIEISELNRVIQ
Sbjct: 347 LDSIIAEVKAQYEDIAQKSKAEAESLYQSKYEELQITAGRHGDSVRNSKIEISELNRVIQ 406
Query: 405 RLQGEIAHVKKQCKNVQDAIADAEQRGEHALKDARNKLNDLEEALQQAKEDLARLLRDYQ 464
RL+ EI +VKKQ N+Q +I+DAEQRGE+ALKDA+NKLNDLE+ALQQAKEDLARLLRDYQ
Sbjct: 407 RLRSEIDNVKKQISNLQQSISDAEQRGENALKDAKNKLNDLEDALQQAKEDLARLLRDYQ 466
Query: 465 ELMNVKLALDVEIATYRKLLEGEECRMSGDLSSNVTVSVTSSTISSNVASKAAFGGSGGR 524
ELMN KLALD+EIATYR LLEGEE RMSG+ + NV+VSV ST + ++ + GG GG
Sbjct: 467 ELMNTKLALDLEIATYRTLLEGEESRMSGECAPNVSVSV--STSHTTISGGGSRGGGGGG 524
Query: 525 GSSSGGGYSSGSSSYGSGGRQSGSRGGSGGGGSI---SGGGYGSGGGSGGR--YGSG--- 576
S G Y SG SYGSGG G RG G GGS GG YGSGGG GG YGSG
Sbjct: 525 YGSGGSSYGSGGGSYGSGGGGGGGRGSYGSGGSSYGSGGGSYGSGGGGGGHGSYGSGSSS 584
Query: 577 GGSKGGSISGGGYGSGGGKHSSGGGSRGGSSSGGGYGSGG----GGSSSVK 623
GG +GGS GGG GS GG+ SGGGS GGS G G SGG GGSSSVK
Sbjct: 585 GGYRGGS-GGGGGGSSGGR-GSGGGSSGGSIGGRGSSSGGVKSSGGSSSVK 633
Score = 89.7 bits (221), Expect = 7e-18
Identities = 65/152 (42%), Positives = 71/152 (46%), Gaps = 30/152 (19%)
Query: 9 SRGRGGGGGGFRGFSSGSAVVSGGSRRSTSSFSCLSRHGGGGGGFGGGGFGSRSLVGLGG 68
SRG GGGG G G S GS GGG G GGGG G R G GG
Sbjct: 517 SRGGGGGGYGSGGSSYGS--------------------GGGSYGSGGGGGGGRGSYGSGG 556
Query: 69 TKSISISVAGGGGGFGAAGGFGGRGGGFGGGSSFGGGSGFSGGGFGGGGFGGGRFGGFGG 128
+ S GGG +G+ GG GG G +G GSS GG G SGG GGGG GGR G G
Sbjct: 557 S-----SYGSGGGSYGSGGGGGGHGS-YGSGSSSGGYRGGSGG--GGGGSSGGRGSGGGS 608
Query: 129 PGG-VGGLG-GPGGFGPGGYPGGIHEVSVNQS 158
GG +GG G GG G + VS S
Sbjct: 609 SGGSIGGRGSSSGGVKSSGGSSSVKFVSTTYS 640
Score = 63.2 bits (152), Expect = 7e-10
Identities = 44/123 (35%), Positives = 51/123 (41%), Gaps = 38/123 (30%)
Query: 548 SRGGSGGGGSISGGGYGSG-------------------GGSGGRYGSGGGSKGGSISGGG 588
SR S G SGGG+ SG GG GGR+ S GG G +GGG
Sbjct: 2 SRQFSSRSGYRSGGGFSSGSAGIINYQRRTTSSSTRRSGGGGGRFSSCGGGGGSFGAGGG 61
Query: 589 YGS------------------GGGKHSS-GGGSRGGSSSGGGYGSGGGGSSSVKGSSGEA 629
+GS GGG+ S GGG GG GGG+G GG G + G
Sbjct: 62 FGSRSLVNLGGSKSISISVARGGGRGSGFGGGYGGGGFGGGGFGGGGFGGGGIGGGGFGG 121
Query: 630 FGS 632
FGS
Sbjct: 122 FGS 124
Score = 37.7 bits (86), Expect = 0.033
Identities = 25/70 (35%), Positives = 30/70 (42%), Gaps = 5/70 (7%)
Query: 9 SRGRGGGGGGFRGFSSGSAVVSGGSRRSTSSFSCLSRHGGGGGGFGGGGFGSRSLVGLGG 68
S G G GG+RG S G S G R S S GG GG G G +S G
Sbjct: 577 SYGSGSSSGGYRGGSGGGGGGSSGGRGSGGGSS-----GGSIGGRGSSSGGVKSSGGSSS 631
Query: 69 TKSISISVAG 78
K +S + +G
Sbjct: 632 VKFVSTTYSG 641
Score = 34.7 bits (78), Expect = 0.28
Identities = 23/59 (38%), Positives = 26/59 (44%), Gaps = 4/59 (6%)
Query: 585 SGGGYGSGGGKHSSGGG----SRGGSSSGGGYGSGGGGSSSVKGSSGEAFGSSVTFSFR 639
S GY SGGG S G R +SS GGGG S G G +FG+ F R
Sbjct: 7 SRSGYRSGGGFSSGSAGIINYQRRTTSSSTRRSGGGGGRFSSCGGGGGSFGAGGGFGSR 65
>gi|109148552 keratin 3 [Homo sapiens]
Length = 628
Score = 704 bits (1816), Expect = 0.0
Identities = 402/626 (64%), Positives = 457/626 (73%), Gaps = 57/626 (9%)
Query: 16 GGGFRGFSSGSAVVSGGSRRSTSSFSCLSRHGGGGGGF-----GGGGFGSRSLVGLGGTK 70
GGG +GFS SAVVSG SR SC++ GG GGG G GGFGSRSL LGG K
Sbjct: 10 GGGSQGFSGRSAVVSGSSR-----MSCVAHSGGAGGGAYGFRSGAGGFGSRSLYNLGGNK 64
Query: 71 SISISVAGGG---GGFGA-------AGGFGGR---------GGGFGGGSSFGGGSGFSGG 111
SISISVA GG GGFG AGG+GG GGGFGGG GGG G +GG
Sbjct: 65 SISISVAAGGSRAGGFGGGRSSCAFAGGYGGGFGSGYGGGFGGGFGGGRGMGGGFGGAGG 124
Query: 112 -----GFGG-GGFGG-GRFGGFGGPGGVGGLGGPGGFGPGGYPGGIHEVSVNQSLLQPLN 164
GFGG GGFGG G FGG GG GG G LG PGGFGPGG+PGGI EV++NQSLLQPLN
Sbjct: 125 FGGAGGFGGAGGFGGPGGFGGSGGFGGPGSLGSPGGFGPGGFPGGIQEVTINQSLLQPLN 184
Query: 165 VKVDPEIQNVKAQEREQIKTLNNKFASFIDKVRFLEQQNQVLQTKWELLQQMNVGTRPI- 223
V++DP+I VKAQEREQIKTLNNKFASFIDKVRFLEQQN+VL+TKW LLQQ GT I
Sbjct: 185 VEIDPQIGQVKAQEREQIKTLNNKFASFIDKVRFLEQQNKVLETKWNLLQQQ--GTSSIS 242
Query: 224 ---NLEPIFQGYIDSLKRYLDGLTAERTSQNSELNNMQDLVEDYKKKYEDEINKRTAAEN 280
NLEP+F+ +I+ L+ YLD + ER +SEL NM+DLVED+KKKYEDEINKRTAAEN
Sbjct: 243 GTNNLEPLFENHINYLRSYLDNILGERGRLDSELKNMEDLVEDFKKKYEDEINKRTAAEN 302
Query: 281 DFVTLKKDVDNAYMIKVELQSKVDLLNQEIEFLKVLYDAEISQIHQSVTDTNVILSMDNS 340
+FVTLKKDVD+AYM KVELQ+KVD L EI+FL+ LYDAE+SQ+ ++DT+V+LSMDN+
Sbjct: 303 EFVTLKKDVDSAYMNKVELQAKVDALIDEIDFLRTLYDAELSQMQSHISDTSVVLSMDNN 362
Query: 341 RNLDLDSIIAEVKAQYEEIAQRSKEEAEALYHSKYEELQVTVGRHGDSLKEIKIEISELN 400
R+LDLDSIIAEV+AQYE+IAQRSK EAEALY +K ELQ T GRHGD L+ K EI ELN
Sbjct: 363 RSLDLDSIIAEVRAQYEDIAQRSKAEAEALYQTKLGELQTTAGRHGDDLRNTKSEIIELN 422
Query: 401 RVIQRLQGEIAHVKKQCKNVQDAIADAEQRGEHALKDARNKLNDLEEALQQAKEDLARLL 460
R+IQRL+ EI VKKQ N+Q AIA+AEQ GE ALKDA KL +L+ ALQQAK+DLARLL
Sbjct: 423 RMIQRLRAEIEGVKKQNANLQTAIAEAEQHGEMALKDANAKLQELQAALQQAKDDLARLL 482
Query: 461 RDYQELMNVKLALDVEIATYRKLLEGEECRMSGDLSSNVTVSVTSSTISSNVASKAAFGG 520
RDYQELMNVKLALDVEIATYRKLLEGEE RMSG+ S V++SV SS+ +S A G
Sbjct: 483 RDYQELMNVKLALDVEIATYRKLLEGEEYRMSGECPSAVSISVVSSSTTSASAGGYGGGY 542
Query: 521 SGGRGSSSGGGYSSGSSSYGSGGRQSGSRGGSGGGGSISGGGYGSGGGSGGRYGSGGGSK 580
GG G GGG+S+G GG SGS G GGGG I GGG+G GG G GGS
Sbjct: 543 GGGMGGGLGGGFSAG------GG--SGSGFGRGGGGGI-GGGFG-----GGSSGFSGGSG 588
Query: 581 GGSISGGGYGSGGGKHSSGGGSRGGS 606
GSISG YG GG SS +RGGS
Sbjct: 589 FGSISGARYGVSGGGFSS-ASNRGGS 613
Score = 83.2 bits (204), Expect = 7e-16
Identities = 59/134 (44%), Positives = 66/134 (49%), Gaps = 15/134 (11%)
Query: 509 SSNVASKAAFGGSGGR--GSSSGGGYSSGSSSYGSGGRQS--------GSRGGSGGGGSI 558
SS ++ A GG+GG G SG G S Y GG +S GSR G GGG
Sbjct: 26 SSRMSCVAHSGGAGGGAYGFRSGAGGFGSRSLYNLGGNKSISISVAAGGSRAGGFGGGRS 85
Query: 559 S---GGGYGSGGGSGGRYGSGGGSKGGSISGGGYGSGGGKHSSGG-GSRGGSSSGGGY-G 613
S GGYG G GSG G GGG GG GGG+G GG +GG G GG GG+ G
Sbjct: 86 SCAFAGGYGGGFGSGYGGGFGGGFGGGRGMGGGFGGAGGFGGAGGFGGAGGFGGPGGFGG 145
Query: 614 SGGGGSSSVKGSSG 627
SGG G GS G
Sbjct: 146 SGGFGGPGSLGSPG 159
Score = 70.1 bits (170), Expect = 6e-12
Identities = 45/118 (38%), Positives = 53/118 (44%), Gaps = 7/118 (5%)
Query: 508 ISSNVASKAAFGGSGGRGSSSGGGYSSGSSSYGSGGRQSGSRGGSGGGGSISGGGYGSGG 567
+ N + + G R GGG SS + + G GG GG GGG G G G G
Sbjct: 60 LGGNKSISISVAAGGSRAGGFGGGRSSCAFAGGYGGGFGSGYGGGFGGGFGGGRGMGGGF 119
Query: 568 GSGGRYGSGGGSKGGSISGGGYGSGGGKHSSGG-GSRGGSSSGGGYGSGG--GGSSSV 622
G G +G GG G GG+G GG SGG G G S GG+G GG GG V
Sbjct: 120 GGAGGFGGAGGFGG----AGGFGGPGGFGGSGGFGGPGSLGSPGGFGPGGFPGGIQEV 173
Score = 38.9 bits (89), Expect = 0.015
Identities = 25/52 (48%), Positives = 27/52 (51%), Gaps = 8/52 (15%)
Query: 11 GRGGGGGGFRGFSSGSAVVSGGSRRSTSSFSCLSRHGGGGGGFGGGGFGSRS 62
GRGGGGG GF GS+ SGGS F +S G G GGGF S S
Sbjct: 565 GRGGGGGIGGGFGGGSSGFSGGS-----GFGSIS---GARYGVSGGGFSSAS 608
>gi|153791670 keratin 76 [Homo sapiens]
Length = 638
Score = 702 bits (1811), Expect = 0.0
Identities = 393/629 (62%), Positives = 447/629 (71%), Gaps = 34/629 (5%)
Query: 17 GGFRGFSSGSAVVSGGSRRSTSSFSCLSRHGGGGGGF-----GGGGFGSRSLVGLGGTKS 71
G +GFS SAVVSG SR SC++R GG GGG G G FGSRSL LG KS
Sbjct: 12 GRSQGFSGRSAVVSGSSR-----MSCVARSGGAGGGACGFRSGAGSFGSRSLYNLGSNKS 66
Query: 72 ISISVAGG-------GGGFGAAGGFGGRGGGFGG--GSSFGGGSGFSGGGFGGGGFGGGR 122
ISISVA G GGG + G GG GGGFGG G FGGG G G G GGFGG
Sbjct: 67 ISISVAAGSSRAGGFGGGRSSCGFAGGYGGGFGGSYGGGFGGGRGVGSGFGGAGGFGGA- 125
Query: 123 FGGFGGPG---GVGGLGGPGGFGPGGYPGGIHEVSVNQSLLQPLNVKVDPEIQNVKAQER 179
GGFGGPG G G GGPGGFGPGG+PGGI EV VNQSLLQPLNV++DP+I VKAQER
Sbjct: 126 -GGFGGPGVFGGPGSFGGPGGFGPGGFPGGIQEVIVNQSLLQPLNVEIDPQIGQVKAQER 184
Query: 180 EQIKTLNNKFASFIDKVRFLEQQNQVLQTKWELLQQMNVGTRPINLEPIFQGYIDSLKRY 239
EQIKTLNNKFASFIDKVRFLEQQN+VL+TKWELLQQ G+ P +LEP F+ YI L +
Sbjct: 185 EQIKTLNNKFASFIDKVRFLEQQNKVLETKWELLQQQTTGSGPSSLEPCFESYISFLCKQ 244
Query: 240 LDGLTAERTSQNSELNNMQDLVEDYKKKYEDEINKRTAAENDFVTLKKDVDNAYMIKVEL 299
LD L ER + EL +MQDLVED+KKKYEDEINKRTAAEN+FV LKKDVD A+M KVEL
Sbjct: 245 LDSLLGERGNLEGELKSMQDLVEDFKKKYEDEINKRTAAENEFVGLKKDVDAAFMNKVEL 304
Query: 300 QSKVDLLNQEIEFLKVLYDAEISQIHQSVTDTNVILSMDNSRNLDLDSIIAEVKAQYEEI 359
Q+KVD L E+ FL+ LY+ E+SQ+ +DT+V+LSMDN+R LDL SIIAEV+AQYEEI
Sbjct: 305 QAKVDSLTDEVSFLRTLYEMELSQMQSHASDTSVVLSMDNNRCLDLGSIIAEVRAQYEEI 364
Query: 360 AQRSKEEAEALYHSKYEELQVTVGRHGDSLKEIKIEISELNRVIQRLQGEIAHVKKQCKN 419
AQRSK EAEALY +K ELQ T GRHGD L+ K EI ELNR+IQRL+ EI +VKKQ N
Sbjct: 365 AQRSKSEAEALYQTKLGELQTTAGRHGDDLRNTKSEIMELNRMIQRLRAEIENVKKQNAN 424
Query: 420 VQDAIADAEQRGEHALKDARNKLNDLEEALQQAKEDLARLLRDYQELMNVKLALDVEIAT 479
+Q AIA+AEQRGE ALKDA KL DL+ ALQ+AK+DLARLLRDYQELMNVKLALDVEIAT
Sbjct: 425 LQTAIAEAEQRGEMALKDANAKLQDLQTALQKAKDDLARLLRDYQELMNVKLALDVEIAT 484
Query: 480 YRKLLEGEECRMSGDLSSNVTVSVTSSTISSNVASKAAFGGSGGRGSSSGGGYSSGSSSY 539
YRKLLEGEECRMSG+ S V +SV S+ S++ +S ++ G GG S GGY GSSS
Sbjct: 485 YRKLLEGEECRMSGECQSAVCISVVSNVTSTSGSSGSSRGVFGGVSGSGSGGYKGGSSSS 544
Query: 540 GSGGRQSGSRGGSGGG-GSISGGGYGSGGGSGGRYGSGGGSKGGSISGGGYGSGGGKHSS 598
S G G GGSG G G +S G G G SG S GS+ GG GS HS
Sbjct: 545 SSSG--YGVSGGSGSGYGGVSSGSTGGRGSSGSYQSSSSGSR-----LGGAGSISVSHSG 597
Query: 599 GGGSRGG--SSSGGGYGSGGGGSSSVKGS 625
G S G +S G GY SGGGGS+S++ S
Sbjct: 598 MGSSSGSIQTSGGSGYKSGGGGSTSIRFS 626
Score = 67.8 bits (164), Expect = 3e-11
Identities = 51/123 (41%), Positives = 58/123 (47%), Gaps = 8/123 (6%)
Query: 509 SSNVASKAAFGGSGGR--GSSSGGGYSSGSSSYGSGGRQSGSRGGSGGGGSISGGGYGSG 566
SS ++ A GG+GG G SG G S Y G +S S S GS GG+G G
Sbjct: 27 SSRMSCVARSGGAGGGACGFRSGAGSFGSRSLYNLGSNKSISI--SVAAGSSRAGGFGGG 84
Query: 567 GGSGGRYGSGGGSKGGSISGGGYGSGGGKHSSGGGSRGGSSSGGGYGSGG--GGSSSVKG 624
S G G GG GGS GGG+G G G SG G GG GG+G G GG S G
Sbjct: 85 RSSCGFAGGYGGGFGGSY-GGGFGGGRGV-GSGFGGAGGFGGAGGFGGPGVFGGPGSFGG 142
Query: 625 SSG 627
G
Sbjct: 143 PGG 145
Score = 55.5 bits (132), Expect = 2e-07
Identities = 49/137 (35%), Positives = 57/137 (41%), Gaps = 18/137 (13%)
Query: 515 KAAFGGSGGRGSSSGGGYSSGSS-------SYGSGGRQSGSRGGSGGGGSISGGGYGSG- 566
K +F G +G S SGSS S G+GG G R G+G GS S GS
Sbjct: 7 KKSFSGRS-QGFSGRSAVVSGSSRMSCVARSGGAGGGACGFRSGAGSFGSRSLYNLGSNK 65
Query: 567 ------GGSGGRYGSGGGSKGGSISGGGYGSGGGKHSSGGGSRGGSSSGGGYGSGGG-GS 619
R G GG + GGYG G G S GGG GG G G+G GG G
Sbjct: 66 SISISVAAGSSRAGGFGGGRSSCGFAGGYGGGFGG-SYGGGFGGGRGVGSGFGGAGGFGG 124
Query: 620 SSVKGSSGEAFGSSVTF 636
+ G G FG +F
Sbjct: 125 AGGFGGPG-VFGGPGSF 140
Score = 48.5 bits (114), Expect = 2e-05
Identities = 45/146 (30%), Positives = 55/146 (37%), Gaps = 8/146 (5%)
Query: 19 FRGFSSGSAVVSGGSRRSTSSFSCLSR--HGGGGGGFGGGGFGSRSLVGLGGTK--SISI 74
+R G G +S S +S G G G FG S G GG K S S
Sbjct: 485 YRKLLEGEECRMSGECQSAVCISVVSNVTSTSGSSGSSRGVFGGVSGSGSGGYKGGSSSS 544
Query: 75 SVAGGGGGFGAAGGFGGRGGGFGGGSSFGGG--SGFSGGGFGGGGFGGGRFGGFGGPGGV 132
S +G G G+ G+GG G GG G S SG GG G G G G
Sbjct: 545 SSSGYGVSGGSGSGYGGVSSGSTGGRGSSGSYQSSSSGSRLGGAGSISVSHSGMGSSSGS 604
Query: 133 GGLGGPGGFGPGGYPGGIHEVSVNQS 158
G G+ GG GG + +Q+
Sbjct: 605 IQTSGGSGYKSGG--GGSTSIRFSQT 628
>gi|119395754 keratin 5 [Homo sapiens]
Length = 590
Score = 647 bits (1669), Expect = 0.0
Identities = 359/580 (61%), Positives = 421/580 (72%), Gaps = 29/580 (5%)
Query: 17 GGFRGFSSGSAVVSGGSRRSTSSFSCLSRHGGGGGG----------FGGGGFGSRSLVGL 66
GG R FS+ SA+ SR +SF+ +SR GGGGGG G GG+GSRSL L
Sbjct: 12 GGSRSFSTASAITPSVSR---TSFTSVSRSGGGGGGGFGRVSLAGACGVGGYGSRSLYNL 68
Query: 67 GGTKSISISVAGGGGGFGAAGGFGGR-GGGFGGGSSFGGGSGFSGGGFGGGGFGGGRFGG 125
GG+K ISIS +GG F R G G GGG FGGG+G SG GFGGG GG FG
Sbjct: 69 GGSKRISISTSGGS--------FRNRFGAGAGGGYGFGGGAG-SGFGFGGGA--GGGFGL 117
Query: 126 FGGPGGVGGLGGPGGFGPGGYPGGIHEVSVNQSLLQPLNVKVDPEIQNVKAQEREQIKTL 185
GG G GG GGPG P PGGI EV+VNQSLL PLN+++DP IQ V+ +EREQIKTL
Sbjct: 118 GGGAGFGGGFGGPGF--PVCPPGGIQEVTVNQSLLTPLNLQIDPSIQRVRTEEREQIKTL 175
Query: 186 NNKFASFIDKVRFLEQQNQVLQTKWELLQQMNVGTRPINLEPIFQGYIDSLKRYLDGLTA 245
NNKFASFIDKVRFLEQQN+VL TKW LLQ+ T NLEP+F+ YI++L+R LD +
Sbjct: 176 NNKFASFIDKVRFLEQQNKVLDTKWTLLQEQGTKTVRQNLEPLFEQYINNLRRQLDSIVG 235
Query: 246 ERTSQNSELNNMQDLVEDYKKKYEDEINKRTAAENDFVTLKKDVDNAYMIKVELQSKVDL 305
ER +SEL NMQDLVED+K KYEDEINKRT AEN+FV LKKDVD AYM KVEL++KVD
Sbjct: 236 ERGRLDSELRNMQDLVEDFKNKYEDEINKRTTAENEFVMLKKDVDAAYMNKVELEAKVDA 295
Query: 306 LNQEIEFLKVLYDAEISQIHQSVTDTNVILSMDNSRNLDLDSIIAEVKAQYEEIAQRSKE 365
L EI F+K+ +DAE+SQ+ V+DT+V+LSMDN+RNLDLDSIIAEVKAQYEEIA RS+
Sbjct: 296 LMDEINFMKMFFDAELSQMQTHVSDTSVVLSMDNNRNLDLDSIIAEVKAQYEEIANRSRT 355
Query: 366 EAEALYHSKYEELQVTVGRHGDSLKEIKIEISELNRVIQRLQGEIAHVKKQCKNVQDAIA 425
EAE+ Y +KYEELQ T GRHGD L+ K EISE+NR+IQRL+ EI +VKKQC N+Q+AIA
Sbjct: 356 EAESWYQTKYEELQQTAGRHGDDLRNTKHEISEMNRMIQRLRAEIDNVKKQCANLQNAIA 415
Query: 426 DAEQRGEHALKDARNKLNDLEEALQQAKEDLARLLRDYQELMNVKLALDVEIATYRKLLE 485
DAEQRGE ALKDARNKL +LEEALQ+AK+D+ARLLR+YQELMN KLALDVEIATYRKLLE
Sbjct: 416 DAEQRGELALKDARNKLAELEEALQKAKQDMARLLREYQELMNTKLALDVEIATYRKLLE 475
Query: 486 GEECRMSGDLSSNVTVSVTSSTISSNVASKAAFGGSGGRGSSSGGGYSSGSSSYGSGGRQ 545
GEECR+SG+ V +SV +S++SS S + +G GG G GGG G + SG
Sbjct: 476 GEECRLSGEGVGPVNISVVTSSVSSGYGSGSGYG--GGLGGGLGGGLGGGLAGGSSGSYY 533
Query: 546 SGSRGGSGGGGSISGGGYGSGGGSGGRYGSGGGSKGGSIS 585
S S GG G GG +S GG G SG G G GS GGS S
Sbjct: 534 SSSSGGVGLGGGLSVGGSGFSASSGRGLGVGFGSGGGSSS 573
Score = 64.7 bits (156), Expect = 2e-10
Identities = 50/130 (38%), Positives = 66/130 (50%), Gaps = 27/130 (20%)
Query: 496 SSNVTVSVTSSTISSNVASKAAFGGSGGRGSSSG----GGYSSGSSSYGSGGRQSGSRGG 551
+S +T SV+ ++ +S S GG GR S +G GGY S S Y GG + S
Sbjct: 20 ASAITPSVSRTSFTSVSRSGGGGGGGFGRVSLAGACGVGGYGS-RSLYNLGGSKRISIST 78
Query: 552 SGGG-----GSISGGGYGSGGGSGGRYGSGGGSKGGSISGGGYGSGGGKHSSGGGSRGGS 606
SGG G+ +GGGYG GGG+G +G GGG+ GGG+G G GG+
Sbjct: 79 SGGSFRNRFGAGAGGGYGFGGGAGSGFGFGGGA------GGGFG-------LG----GGA 121
Query: 607 SSGGGYGSGG 616
GGG+G G
Sbjct: 122 GFGGGFGGPG 131
Score = 53.9 bits (128), Expect = 4e-07
Identities = 42/123 (34%), Positives = 53/123 (43%), Gaps = 8/123 (6%)
Query: 514 SKAAFGGSGGRGSSSGGGYSSGSS--SYGSGGRQSGSRGGSGGGGSISGGGYGSGGGSGG 571
S +F G R S+ + S S+ S R G GG GG G +S G GG G
Sbjct: 5 SSVSFRSGGSRSFSTASAITPSVSRTSFTSVSRSGG--GGGGGFGRVSLAGACGVGGYGS 62
Query: 572 R--YGSGGGSKGG-SISGGGYGSGGGKHSSGGGSRGGSSSGGGYGSGGGGSSSVKGSSGE 628
R Y GG + S SGG + + G +GGG G +G G+G GGG G
Sbjct: 63 RSLYNLGGSKRISISTSGGSFRNRFGA-GAGGGYGFGGGAGSGFGFGGGAGGGFGLGGGA 121
Query: 629 AFG 631
FG
Sbjct: 122 GFG 124
Score = 42.4 bits (98), Expect = 0.001
Identities = 39/107 (36%), Positives = 42/107 (39%), Gaps = 31/107 (28%)
Query: 1 MSCQISCKSRGRGGGGGGFRGFSSGSAVVSGGSRRSTSSFSCLSRHGGGGGGFGGGGFG- 59
+S S S G G G G G G GG GGG GG G
Sbjct: 491 ISVVTSSVSSGYGSGSGYGGGLGGGLG-------------------GGLGGGLAGGSSGS 531
Query: 60 ----SRSLVGLGGTKSISISVAGGGGGFGAAGGFG-GRGGGFGGGSS 101
S VGLGG S+ GG GF A+ G G G G G GGGSS
Sbjct: 532 YYSSSSGGVGLGGGLSV------GGSGFSASSGRGLGVGFGSGGGSS 572
Score = 34.7 bits (78), Expect = 0.28
Identities = 26/61 (42%), Positives = 28/61 (45%), Gaps = 2/61 (3%)
Query: 13 GGGGGGFRGFSSGSAVVSGGSRRSTSSFSCLSRHGGGGGGFGGGGFGSRSLVGLGGTKSI 72
GG G + SSG + GG S FS S G G G FG GG GS S V T S
Sbjct: 526 GGSSGSYYSSSSGGVGLGGGLSVGGSGFSASSGRGLGVG-FGSGG-GSSSSVKFVSTTSS 583
Query: 73 S 73
S
Sbjct: 584 S 584
Score = 31.2 bits (69), Expect = 3.1
Identities = 19/38 (50%), Positives = 20/38 (52%), Gaps = 1/38 (2%)
Query: 597 SSGGGSRGGSSSGGGYGSGGG-GSSSVKGSSGEAFGSS 633
SSG GS G G G G GGG G GSSG + SS
Sbjct: 499 SSGYGSGSGYGGGLGGGLGGGLGGGLAGGSSGSYYSSS 536
>gi|194018511 keratin 77 [Homo sapiens]
Length = 578
Score = 633 bits (1632), Expect = 0.0
Identities = 343/569 (60%), Positives = 412/569 (72%), Gaps = 31/569 (5%)
Query: 20 RGFSSGSAVVSGGSRRSTSSFSCLSRHGGGGGGFG--GGGFGSRSLVGLGGTKSISISVA 77
R +S+ S+ SGG + S C +R GGGG+G G GFGSRSL LGG++SISI++
Sbjct: 17 RVYSTSSSAGSGGGSPAVGSV-CYARGRCGGGGYGIHGRGFGSRSLYNLGGSRSISINLM 75
Query: 78 GGG-GGFGAAGGFGGRGGGFGGGSSFGGGSGFSGGGFGGGGFGGGRFGGFGGPGGVGGLG 136
G GF GG GG GGG G G G GF GGGFGG GFG FG
Sbjct: 76 GRSTSGFCQGGGVGGFGGGRGFGVGSTGAGGFGGGGFGGAGFGTSNFG------------ 123
Query: 137 GPGGFGPGGYPGGIHEVSVNQSLLQPLNVKVDPEIQNVKAQEREQIKTLNNKFASFIDKV 196
GGFGP PGGI EV++NQSLL+PL+++VDPEIQ +K QEREQI LNNKFASFIDKV
Sbjct: 124 -LGGFGPYCPPGGIQEVTINQSLLEPLHLEVDPEIQRIKTQEREQIMVLNNKFASFIDKV 182
Query: 197 RFLEQQNQVLQTKWELLQQMNVGTRPINLEPIFQGYIDSLKRYLDGLTAERTSQNSELNN 256
RFLEQQNQVLQTKWELLQQ+N T NLEP+ + YI L+R +D L+AE+ QN+E+ +
Sbjct: 183 RFLEQQNQVLQTKWELLQQVNTSTGTNNLEPLLENYIGDLRRQVDLLSAEQMRQNAEVRS 242
Query: 257 MQDLVEDYKKKYEDEINKRTAAENDFVTLKKDVDNAYMIKVELQSKVDLLNQEIEFLKVL 316
MQD+VEDYK KYEDEINKRT +ENDFV LKKDVD AY+ KV+L+S+VD L E+ FLK L
Sbjct: 243 MQDVVEDYKSKYEDEINKRTGSENDFVVLKKDVDAAYVSKVDLESRVDTLTGEVNFLKYL 302
Query: 317 YDAEISQIHQSVTDTNVILSMDNSRNLDLDSIIAEVKAQYEEIAQRSKEEAEALYHSKYE 376
+ E+SQ+ ++DTNVILSMDN+R+LDLDSII V+ QYE IAQRSK+EAEALY +KY+
Sbjct: 303 FLTELSQVQTHISDTNVILSMDNNRSLDLDSIIDAVRTQYELIAQRSKDEAEALYQTKYQ 362
Query: 377 ELQVTVGRHGDSLKEIKIEISELNRVIQRLQGEIAHVKKQCKNVQDAIADAEQRGEHALK 436
ELQ+T GRHGD LK K+EI+ELNR +QRLQ EI++VKKQ + +Q I+DAE+RGE AL+
Sbjct: 363 ELQITAGRHGDDLKNSKMEIAELNRTVQRLQAEISNVKKQIEQMQSLISDAEERGEQALQ 422
Query: 437 DARNKLNDLEEALQQAKEDLARLLRDYQELMNVKLALDVEIATYRKLLEGEECRMSGDLS 496
DA KL DLEEALQQ+KE+LARLLRDYQ ++ VKL+LDVEIATYR+LLEGEE RMSG+L
Sbjct: 423 DAWQKLQDLEEALQQSKEELARLLRDYQAMLGVKLSLDVEIATYRQLLEGEESRMSGELQ 482
Query: 497 SNVTVSVTSSTISSNVASKAAFGGSGGRGSSSGGGYSSGSSSYGSGGRQSGSRGGSGGGG 556
S+V++SV +S +S N GG+GG GS GGY GSGG G R GGG
Sbjct: 483 SHVSISVQNSQVSVN-------GGAGGGGSYGSGGYGG-----GSGGGYGGGRSYRGGGA 530
Query: 557 -SISGGGYGSG-GGSGGRYGSGGGSKGGS 583
SGGGYGSG GG GG YG G S GS
Sbjct: 531 RGRSGGGYGSGCGGGGGSYGGSGRSGRGS 559
Score = 59.3 bits (142), Expect = 1e-08
Identities = 50/133 (37%), Positives = 58/133 (43%), Gaps = 15/133 (11%)
Query: 491 MSGDLSSNVTVSVTSSTISSNVASKAAFGGSGGRGSSSGGGYSSGSSSYGSGGRQSGSRG 550
MS SS S S + S +S + GGS GS G YG GR GSR
Sbjct: 1 MSHQFSSQSAFSSMSRRVYSTSSSAGSGGGSPAVGSVCYARGRCGGGGYGIHGRGFGSRS 60
Query: 551 --GSGGGGSI-------SGGGYGSGGGSGGRYGSGGGSKGGSISGGGYGSGGGKHSSGGG 601
GG SI S G+ GGG GG +G G G GS GG+G GG GG
Sbjct: 61 LYNLGGSRSISINLMGRSTSGFCQGGGVGG-FGGGRGFGVGSTGAGGFGGGG----FGGA 115
Query: 602 SRGGSSSG-GGYG 613
G S+ G GG+G
Sbjct: 116 GFGTSNFGLGGFG 128
Score = 58.9 bits (141), Expect = 1e-08
Identities = 46/124 (37%), Positives = 57/124 (45%), Gaps = 13/124 (10%)
Query: 508 ISSNVASKAAFGGSGGR--GSSSGGGYSSGSSSYGSGGRQSGSRGGSGGGG-SISGGGYG 564
+S +S++AF R +SS G GS + GS +RG GGGG I G G+G
Sbjct: 1 MSHQFSSQSAFSSMSRRVYSTSSSAGSGGGSPAVGS---VCYARGRCGGGGYGIHGRGFG 57
Query: 565 S------GGGSGGRYGSGGGSKGGSISGGGYGSGGGKHSSGGGSRG-GSSSGGGYGSGGG 617
S GG G S G GGG G GG G GS G G GGG+G G
Sbjct: 58 SRSLYNLGGSRSISINLMGRSTSGFCQGGGVGGFGGGRGFGVGSTGAGGFGGGGFGGAGF 117
Query: 618 GSSS 621
G+S+
Sbjct: 118 GTSN 121
Score = 52.4 bits (124), Expect = 1e-06
Identities = 35/76 (46%), Positives = 38/76 (50%), Gaps = 2/76 (2%)
Query: 84 GAAGGFGGRG-GGFGGGSSFGGGSGFSGGGFGGGGFGGGRFGGFGGPGGVGGLGGPGGFG 142
G AGG G G GG+GGGS G G G S G G G GG +G G GG G GG G G
Sbjct: 498 GGAGGGGSYGSGGYGGGSGGGYGGGRSYRGGGARGRSGGGYGS-GCGGGGGSYGGSGRSG 556
Query: 143 PGGYPGGIHEVSVNQS 158
G I + S N S
Sbjct: 557 RGSSRVQIIQTSTNTS 572
Score = 45.8 bits (107), Expect = 1e-04
Identities = 39/106 (36%), Positives = 44/106 (41%), Gaps = 33/106 (31%)
Query: 1 MSCQISCKSRGRGGGGGGFRGFSSGSAVVSGGSRRSTSSFSCLSRHGGGGGGFGGGGFGS 60
+S Q S S G GGGG G GG GGG GGG G
Sbjct: 487 ISVQNSQVSVNGGAGGGGSYG------------------------SGGYGGGSGGGYGGG 522
Query: 61 RSLVGLGGTKSISISVAGGGGGFGAAGGFGGRGGGFGGGSSFGGGS 106
RS G GG + S GGG+G+ G GG GG +GG G GS
Sbjct: 523 RSYRG-GGARGRS------GGGYGS--GCGGGGGSYGGSGRSGRGS 559
Score = 41.6 bits (96), Expect = 0.002
Identities = 43/124 (34%), Positives = 52/124 (41%), Gaps = 31/124 (25%)
Query: 527 SSGGGYSSGSSSYGSGGRQSGSRGGSGGGGSISGGGYGSGGGSGGRYGSGGGSKGGSISG 586
SS +SS S S +GS GGS GS+ Y G GG YG I G
Sbjct: 6 SSQSAFSSMSRRVYSTSSSAGSGGGSPAVGSVC---YARGRCGGGGYG---------IHG 53
Query: 587 GGYGSGGGKHSSGGGSR-------GGSSSG-------GGYGSGGG---GSSSVKGSSGEA 629
G+GS + GGSR G S+SG GG+G G G GS+ G G
Sbjct: 54 RGFGSRSLYNL--GGSRSISINLMGRSTSGFCQGGGVGGFGGGRGFGVGSTGAGGFGGGG 111
Query: 630 FGSS 633
FG +
Sbjct: 112 FGGA 115
Score = 37.7 bits (86), Expect = 0.033
Identities = 26/73 (35%), Positives = 30/73 (41%), Gaps = 1/73 (1%)
Query: 4 QISCKSRGRGGGGGGFRGFSSGSAVVSGGSRRSTSSFSCLSRHGGGGGGFGGGGFGSRSL 63
Q+S GGG G G+ GS GG R S R GGG G GGG GS
Sbjct: 493 QVSVNGGAGGGGSYGSGGYGGGSGGGYGGGR-SYRGGGARGRSGGGYGSGCGGGGGSYGG 551
Query: 64 VGLGGTKSISISV 76
G G S + +
Sbjct: 552 SGRSGRGSSRVQI 564
>gi|119703753 keratin 6B [Homo sapiens]
Length = 564
Score = 630 bits (1626), Expect = 0.0
Identities = 354/554 (63%), Positives = 408/554 (73%), Gaps = 27/554 (4%)
Query: 20 RGFSSGSAVVSGGSRRSTSSFSCLSRHGGGG--GGFGGGGFGSRSLVGLGGTKSISISVA 77
RGFS+ SA + G SR SS S G GG G GG GFGSRSL GLGG+K ISI
Sbjct: 16 RGFSANSARLPGVSRSGFSSISVSRSRGSGGLGGACGGAGFGSRSLYGLGGSKRISI--- 72
Query: 78 GGGGGFGAAGGFGGRGGGFGGGSSFGG-GSGFSGGGFGGGGFGGGRFGGFGGPGGVGGLG 136
GGG +GG+G R GG G FGG GSGF GG G GFG G GG G GG G
Sbjct: 73 -GGGSCAISGGYGSRAGGSYG---FGGAGSGFGFGGGAGIGFGLG-----GGAGLAGGFG 123
Query: 137 GPGGFGPGGYPGGIHEVSVNQSLLQPLNVKVDPEIQNVKAQEREQIKTLNNKFASFIDKV 196
GPG P PGGI EV+VNQSLL PLN+++DP IQ V+A+EREQIKTLNNKFASFIDKV
Sbjct: 124 GPGF--PVCPPGGIQEVTVNQSLLTPLNLQIDPAIQRVRAEEREQIKTLNNKFASFIDKV 181
Query: 197 RFLEQQNQVLQTKWELLQQMNVGTRPINLEPIFQGYIDSLKRYLDGLTAERTSQNSELNN 256
RFLEQQN+VL TKW LLQ+ T NLEP+F+ YI++L+R LD + ER +SEL N
Sbjct: 182 RFLEQQNKVLDTKWTLLQEQGTKTVRQNLEPLFEQYINNLRRQLDNIVGERGRLDSELRN 241
Query: 257 MQDLVEDYKKKYEDEINKRTAAENDFVTLKKDVDNAYMIKVELQSKVDLLNQEIEFLKVL 316
MQDLVED K KYEDEINKRTAAEN+FVTLKKDVD AYM KVELQ+K D L EI FL+ L
Sbjct: 242 MQDLVEDLKNKYEDEINKRTAAENEFVTLKKDVDAAYMNKVELQAKADTLTDEINFLRAL 301
Query: 317 YDAEISQIHQSVTDTNVILSMDNSRNLDLDSIIAEVKAQYEEIAQRSKEEAEALYHSKYE 376
YDAE+SQ+ ++DT+V+LSMDN+RNLDLDSIIAEVKAQYEEIAQRS+ EAE+ Y +KYE
Sbjct: 302 YDAELSQMQTHISDTSVVLSMDNNRNLDLDSIIAEVKAQYEEIAQRSRAEAESWYQTKYE 361
Query: 377 ELQVTVGRHGDSLKEIKIEISELNRVIQRLQGEIAHVKKQCKNVQDAIADAEQRGEHALK 436
ELQ+T GRHGD L+ K EI+E+NR+IQRL+ EI HVKKQC N+Q AIADAEQRGE ALK
Sbjct: 362 ELQITAGRHGDDLRNTKQEIAEINRMIQRLRSEIDHVKKQCANLQAAIADAEQRGEMALK 421
Query: 437 DARNKLNDLEEALQQAKEDLARLLRDYQELMNVKLALDVEIATYRKLLEGEECRMSGDLS 496
DA+NKL LE+ALQ+AK+DLARLL++YQELMNVKLALDVEIATYRKLLEGEECR++G+
Sbjct: 422 DAKNKLEGLEDALQKAKQDLARLLKEYQELMNVKLALDVEIATYRKLLEGEECRLNGEGV 481
Query: 497 SNVTVSVTSSTISSNVASKAAFGGSGGRGSSSGGGYSSGSSSYGSGGRQSGSRGGSGGGG 556
V +SV ST+SS +GG+ G GS G G S S SYGSG G G S G
Sbjct: 482 GQVNISVVQSTVSS------GYGGASGVGSGLGLGGGS-SYSYGSGLGVGG--GFSSSSG 532
Query: 557 SISGGGYGS-GGGS 569
+GGG S GGGS
Sbjct: 533 RATGGGLSSVGGGS 546
Score = 64.3 bits (155), Expect = 3e-10
Identities = 51/131 (38%), Positives = 63/131 (48%), Gaps = 16/131 (12%)
Query: 504 TSSTISSNVASKAAFGGSGGR-GSSSGGGYSSGSSSYGSGGRQSGSRGGSGGGGSISGGG 562
TS+TI S+ +S+ F + R S G+SS S S SRG G GG+ G G
Sbjct: 4 TSTTIRSHSSSRRGFSANSARLPGVSRSGFSSISVSR--------SRGSGGLGGACGGAG 55
Query: 563 YGSGGGSGGRYGSGGGSKGGSISGGGYGSGGGKHSSGGGSRGGSSSGGGYGSGGGG--SS 620
+GS YG GG SK SI GG GG S GGS G +G G+G GGG
Sbjct: 56 FGSRS----LYGLGG-SKRISIGGGSCAISGGYGSRAGGSYGFGGAGSGFGFGGGAGIGF 110
Query: 621 SVKGSSGEAFG 631
+ G +G A G
Sbjct: 111 GLGGGAGLAGG 121
Score = 63.5 bits (153), Expect = 6e-10
Identities = 46/114 (40%), Positives = 56/114 (49%), Gaps = 15/114 (13%)
Query: 503 VTSSTISSNVASKAAFGGSGGRGSSSGGGYSSGSSSYGSGGRQSGSRGGSGGGGSISGGG 562
V+ S SS S++ GSGG G + GG S YG GG + R GGG GG
Sbjct: 28 VSRSGFSSISVSRSR--GSGGLGGACGGAGFGSRSLYGLGGSK---RISIGGGSCAISGG 82
Query: 563 YGSGGGSGGRYGSGGGSKGGSISGGGYGSGGGKHSSGGGSRGGSSSGGGYGSGG 616
YGS +GG YG GG +G G+G GGG G G GG+ GG+G G
Sbjct: 83 YGSR--AGGSYGFGG-------AGSGFGFGGGA-GIGFGLGGGAGLAGGFGGPG 126
Score = 43.5 bits (101), Expect = 6e-04
Identities = 39/103 (37%), Positives = 43/103 (41%), Gaps = 4/103 (3%)
Query: 538 SYGSGGRQSGSRGGSGGGGSISGGGYGSGGGSGGRYGSGGGSKG-GSISGGGYGSGGGKH 596
S+ S R + G S SG S S G G GG G G S YG GG K
Sbjct: 10 SHSSSRRGFSANSARLPGVSRSGFSSISVSRSRGSGGLGGACGGAGFGSRSLYGLGGSKR 69
Query: 597 SSGGGSRGGSSSGGGYGSGGGGSSSVKGS-SGEAFGSSVTFSF 638
S GG G + GGYGS GGS G+ SG FG F
Sbjct: 70 ISIGG--GSCAISGGYGSRAGGSYGFGGAGSGFGFGGGAGIGF 110
>gi|5031839 keratin 6A [Homo sapiens]
Length = 564
Score = 629 bits (1623), Expect = e-180
Identities = 354/554 (63%), Positives = 408/554 (73%), Gaps = 27/554 (4%)
Query: 20 RGFSSGSAVVSGGSRRSTSSFSCLSRHGGGG--GGFGGGGFGSRSLVGLGGTKSISISVA 77
RGFS+ SA + G SR SS S G GG G GG GFGSRSL GLGG+K ISI
Sbjct: 16 RGFSANSARLPGVSRSGFSSVSVSRSRGSGGLGGACGGAGFGSRSLYGLGGSKRISI--- 72
Query: 78 GGGGGFGAAGGFGGRGGGFGGGSSFGG-GSGFSGGGFGGGGFGGGRFGGFGGPGGVGGLG 136
GGG +GG+G R GG G FGG GSGF GG G GFG G GG G GG G
Sbjct: 73 -GGGSCAISGGYGSRAGGSYG---FGGAGSGFGFGGGAGIGFGLG-----GGAGLAGGFG 123
Query: 137 GPGGFGPGGYPGGIHEVSVNQSLLQPLNVKVDPEIQNVKAQEREQIKTLNNKFASFIDKV 196
GPG P PGGI EV+VNQSLL PLN+++DP IQ V+A+EREQIKTLNNKFASFIDKV
Sbjct: 124 GPGF--PVCPPGGIQEVTVNQSLLTPLNLQIDPTIQRVRAEEREQIKTLNNKFASFIDKV 181
Query: 197 RFLEQQNQVLQTKWELLQQMNVGTRPINLEPIFQGYIDSLKRYLDGLTAERTSQNSELNN 256
RFLEQQN+VL+TKW LLQ+ T NLEP+F+ YI++L+R LD + ER +SEL
Sbjct: 182 RFLEQQNKVLETKWTLLQEQGTKTVRQNLEPLFEQYINNLRRQLDSIVGERGRLDSELRG 241
Query: 257 MQDLVEDYKKKYEDEINKRTAAENDFVTLKKDVDNAYMIKVELQSKVDLLNQEIEFLKVL 316
MQDLVED+K KYEDEINKRTAAEN+FVTLKKDVD AYM KVELQ+K D L EI FL+ L
Sbjct: 242 MQDLVEDFKNKYEDEINKRTAAENEFVTLKKDVDAAYMNKVELQAKADTLTDEINFLRAL 301
Query: 317 YDAEISQIHQSVTDTNVILSMDNSRNLDLDSIIAEVKAQYEEIAQRSKEEAEALYHSKYE 376
YDAE+SQ+ ++DT+V+LSMDN+RNLDLDSIIAEVKAQYEEIAQRS+ EAE+ Y +KYE
Sbjct: 302 YDAELSQMQTHISDTSVVLSMDNNRNLDLDSIIAEVKAQYEEIAQRSRAEAESWYQTKYE 361
Query: 377 ELQVTVGRHGDSLKEIKIEISELNRVIQRLQGEIAHVKKQCKNVQDAIADAEQRGEHALK 436
ELQVT GRHGD L+ K EI+E+NR+IQRL+ EI HVKKQC N+Q AIADAEQRGE ALK
Sbjct: 362 ELQVTAGRHGDDLRNTKQEIAEINRMIQRLRSEIDHVKKQCANLQAAIADAEQRGEMALK 421
Query: 437 DARNKLNDLEEALQQAKEDLARLLRDYQELMNVKLALDVEIATYRKLLEGEECRMSGDLS 496
DA+NKL LE+ALQ+AK+DLARLL++YQELMNVKLALDVEIATYRKLLEGEECR++G+
Sbjct: 422 DAKNKLEGLEDALQKAKQDLARLLKEYQELMNVKLALDVEIATYRKLLEGEECRLNGEGV 481
Query: 497 SNVTVSVTSSTISSNVASKAAFGGSGGRGSSSGGGYSSGSSSYGSGGRQSGSRGGSGGGG 556
V +SV ST+SS +GG+ G GS G G S S SYGSG G G S G
Sbjct: 482 GQVNISVVQSTVSS------GYGGASGVGSGLGLGGGS-SYSYGSGLGVGG--GFSSSSG 532
Query: 557 SISGGGYGS-GGGS 569
GGG S GGGS
Sbjct: 533 RAIGGGLSSVGGGS 546
Score = 64.7 bits (156), Expect = 2e-10
Identities = 52/135 (38%), Positives = 62/135 (45%), Gaps = 19/135 (14%)
Query: 504 TSSTISSNVASKAAFGGSGGR-GSSSGGGYSSGSSSYGSGGRQSGSRGGSGGGGSISGGG 562
TS+TI S+ +S+ F + R S G+SS S S SRG G GG+ G G
Sbjct: 4 TSTTIRSHSSSRRGFSANSARLPGVSRSGFSSVSVSR--------SRGSGGLGGACGGAG 55
Query: 563 YGS----GGGSGGRYGSGGGSKGGSISGGGYGSGGGKHSSGGGSRGGSSSGGGYGSG--- 615
+GS G G R GGGS S GGYGS G GG+ G GGG G G
Sbjct: 56 FGSRSLYGLGGSKRISIGGGSCAIS---GGYGSRAGGSYGFGGAGSGFGFGGGAGIGFGL 112
Query: 616 GGGSSSVKGSSGEAF 630
GGG+ G G F
Sbjct: 113 GGGAGLAGGFGGPGF 127
Score = 63.5 bits (153), Expect = 6e-10
Identities = 46/114 (40%), Positives = 56/114 (49%), Gaps = 15/114 (13%)
Query: 503 VTSSTISSNVASKAAFGGSGGRGSSSGGGYSSGSSSYGSGGRQSGSRGGSGGGGSISGGG 562
V+ S SS S++ GSGG G + GG S YG GG + R GGG GG
Sbjct: 28 VSRSGFSSVSVSRSR--GSGGLGGACGGAGFGSRSLYGLGGSK---RISIGGGSCAISGG 82
Query: 563 YGSGGGSGGRYGSGGGSKGGSISGGGYGSGGGKHSSGGGSRGGSSSGGGYGSGG 616
YGS +GG YG GG +G G+G GGG G G GG+ GG+G G
Sbjct: 83 YGSR--AGGSYGFGG-------AGSGFGFGGGA-GIGFGLGGGAGLAGGFGGPG 126
Score = 43.9 bits (102), Expect = 5e-04
Identities = 39/103 (37%), Positives = 43/103 (41%), Gaps = 4/103 (3%)
Query: 538 SYGSGGRQSGSRGGSGGGGSISGGGYGSGGGSGGRYGSGGGSKG-GSISGGGYGSGGGKH 596
S+ S R + G S SG S S G G GG G G S YG GG K
Sbjct: 10 SHSSSRRGFSANSARLPGVSRSGFSSVSVSRSRGSGGLGGACGGAGFGSRSLYGLGGSKR 69
Query: 597 SSGGGSRGGSSSGGGYGSGGGGSSSVKGS-SGEAFGSSVTFSF 638
S GG G + GGYGS GGS G+ SG FG F
Sbjct: 70 ISIGG--GSCAISGGYGSRAGGSYGFGGAGSGFGFGGGAGIGF 110
>gi|155969697 keratin 6C [Homo sapiens]
Length = 564
Score = 628 bits (1620), Expect = e-180
Identities = 350/549 (63%), Positives = 401/549 (73%), Gaps = 20/549 (3%)
Query: 20 RGFSSGSAVVSGGSRRSTSSFSCLSRHGGGG--GGFGGGGFGSRSLVGLGGTKSISISVA 77
RGFS+ SA + G SR SS S G GG G GG GFGSRSL GLGG+K ISI
Sbjct: 16 RGFSANSARLPGVSRSGFSSISVSRSRGSGGLGGACGGAGFGSRSLYGLGGSKRISI--- 72
Query: 78 GGGGGFGAAGGFGGRGGGFGGGSSFGG-GSGFSGGGFGGGGFGGGRFGGFGGPGGVGGLG 136
GGG +GG+G R GG G FGG GSGF GG G GFG G GG G GG G
Sbjct: 73 -GGGSCAISGGYGSRAGGSYG---FGGAGSGFGFGGGAGIGFGLG-----GGAGLAGGFG 123
Query: 137 GPGGFGPGGYPGGIHEVSVNQSLLQPLNVKVDPEIQNVKAQEREQIKTLNNKFASFIDKV 196
GPG P PGGI EV+VNQSLL PLN+++DP IQ V+A+EREQIKTLNNKFASFIDKV
Sbjct: 124 GPGF--PVCPPGGIQEVTVNQSLLTPLNLQIDPAIQRVRAEEREQIKTLNNKFASFIDKV 181
Query: 197 RFLEQQNQVLQTKWELLQQMNVGTRPINLEPIFQGYIDSLKRYLDGLTAERTSQNSELNN 256
RFLEQQN+VL TKW LLQ+ T NLEP+F+ YI++L+R LD + ER +SEL N
Sbjct: 182 RFLEQQNKVLDTKWTLLQEQGTKTVRQNLEPLFEQYINNLRRQLDSIVGERGRLDSELRN 241
Query: 257 MQDLVEDYKKKYEDEINKRTAAENDFVTLKKDVDNAYMIKVELQSKVDLLNQEIEFLKVL 316
MQDLVED K KYEDEINKRTAAEN+FVTLKKDVD AYM KVELQ+K D L EI FL+ L
Sbjct: 242 MQDLVEDLKNKYEDEINKRTAAENEFVTLKKDVDAAYMNKVELQAKADTLTDEINFLRAL 301
Query: 317 YDAEISQIHQSVTDTNVILSMDNSRNLDLDSIIAEVKAQYEEIAQRSKEEAEALYHSKYE 376
YDAE+SQ+ ++DT+V+LSMDN+RNLDLDSIIAEVKAQYEEIAQRS+ EAE+ Y +KYE
Sbjct: 302 YDAELSQMQTHISDTSVVLSMDNNRNLDLDSIIAEVKAQYEEIAQRSRAEAESWYQTKYE 361
Query: 377 ELQVTVGRHGDSLKEIKIEISELNRVIQRLQGEIAHVKKQCKNVQDAIADAEQRGEHALK 436
ELQVT GRHGD L+ K EI+E+NR+IQRL+ EI HVKKQC ++Q AIADAEQRGE ALK
Sbjct: 362 ELQVTAGRHGDDLRNTKQEIAEINRMIQRLRSEIDHVKKQCASLQAAIADAEQRGEMALK 421
Query: 437 DARNKLNDLEEALQQAKEDLARLLRDYQELMNVKLALDVEIATYRKLLEGEECRMSGDLS 496
DA+NKL LE+ALQ+AK+DLARLL++YQELMNVKLALDVEIATYRKLLEGEECR++G+
Sbjct: 422 DAKNKLEGLEDALQKAKQDLARLLKEYQELMNVKLALDVEIATYRKLLEGEECRLNGEGV 481
Query: 497 SNVTVSVTSSTISSNVASKAAFGGSGGRGSSSGGGYSSGSSSYGSGGRQSGSRGGSGGGG 556
V VSV STISS + G G G S Y SG G GG S S G + GGG
Sbjct: 482 GQVNVSVVQSTISSGYGGASGVGSGLGLGGGSSYSYGSG---LGIGGGFSSSSGRAIGGG 538
Query: 557 SISGGGYGS 565
S GG S
Sbjct: 539 LSSVGGGSS 547
Score = 64.3 bits (155), Expect = 3e-10
Identities = 52/135 (38%), Positives = 62/135 (45%), Gaps = 19/135 (14%)
Query: 504 TSSTISSNVASKAAFGGSGGR-GSSSGGGYSSGSSSYGSGGRQSGSRGGSGGGGSISGGG 562
TS+TI S+ +S+ F + R S G+SS S S SRG G GG+ G G
Sbjct: 4 TSTTIRSHSSSRRGFSANSARLPGVSRSGFSSISVSR--------SRGSGGLGGACGGAG 55
Query: 563 YGS----GGGSGGRYGSGGGSKGGSISGGGYGSGGGKHSSGGGSRGGSSSGGGYGSG--- 615
+GS G G R GGGS S GGYGS G GG+ G GGG G G
Sbjct: 56 FGSRSLYGLGGSKRISIGGGSCAIS---GGYGSRAGGSYGFGGAGSGFGFGGGAGIGFGL 112
Query: 616 GGGSSSVKGSSGEAF 630
GGG+ G G F
Sbjct: 113 GGGAGLAGGFGGPGF 127
Score = 63.5 bits (153), Expect = 6e-10
Identities = 46/114 (40%), Positives = 56/114 (49%), Gaps = 15/114 (13%)
Query: 503 VTSSTISSNVASKAAFGGSGGRGSSSGGGYSSGSSSYGSGGRQSGSRGGSGGGGSISGGG 562
V+ S SS S++ GSGG G + GG S YG GG + R GGG GG
Sbjct: 28 VSRSGFSSISVSRSR--GSGGLGGACGGAGFGSRSLYGLGGSK---RISIGGGSCAISGG 82
Query: 563 YGSGGGSGGRYGSGGGSKGGSISGGGYGSGGGKHSSGGGSRGGSSSGGGYGSGG 616
YGS +GG YG GG +G G+G GGG G G GG+ GG+G G
Sbjct: 83 YGSR--AGGSYGFGG-------AGSGFGFGGGA-GIGFGLGGGAGLAGGFGGPG 126
Score = 43.5 bits (101), Expect = 6e-04
Identities = 39/103 (37%), Positives = 43/103 (41%), Gaps = 4/103 (3%)
Query: 538 SYGSGGRQSGSRGGSGGGGSISGGGYGSGGGSGGRYGSGGGSKG-GSISGGGYGSGGGKH 596
S+ S R + G S SG S S G G GG G G S YG GG K
Sbjct: 10 SHSSSRRGFSANSARLPGVSRSGFSSISVSRSRGSGGLGGACGGAGFGSRSLYGLGGSKR 69
Query: 597 SSGGGSRGGSSSGGGYGSGGGGSSSVKGS-SGEAFGSSVTFSF 638
S GG G + GGYGS GGS G+ SG FG F
Sbjct: 70 ISIGG--GSCAISGGYGSRAGGSYGFGGAGSGFGFGGGAGIGF 110
>gi|109255249 keratin 4 [Homo sapiens]
Length = 594
Score = 579 bits (1493), Expect = e-165
Identities = 329/544 (60%), Positives = 393/544 (72%), Gaps = 49/544 (9%)
Query: 17 GGFRGFSSGSAVVSGGSRRSTSSFSCLSRHGGGGGGFGGGGFGSRSLVGLGGTKSISISV 76
GG RGFS GSA+V GG R + SS S GG G GGFGSRSL L G KSIS+SV
Sbjct: 84 GGPRGFSCGSAIVGGGKRGAFSSVSM----SGGAGRCSSGGFGSRSLYNLRGNKSISMSV 139
Query: 77 AGGGGGFGAAGGFGGRGGGFGGGSSFGGGSGFSGGGFGGGGFGGGRFGGFGGPGGVGGLG 136
AG +G FGG FG GGFGGG GG F G GGPG
Sbjct: 140 AGSR-----------QGACFGGAGGFG------TGGFGGG--FGGSFSGKGGPG------ 174
Query: 137 GPGGFGPGGYPGGIHEVSVNQSLLQPLNVKVDPEIQNVKAQEREQIKTLNNKFASFIDKV 196
P GGI EV++NQSLL PL+V++DPEIQ V+ +EREQIK LNNKFASFIDKV
Sbjct: 175 -----FPVCPAGGIQEVTINQSLLTPLHVEIDPEIQKVRTEEREQIKLLNNKFASFIDKV 229
Query: 197 RFLEQQNQVLQTKWELLQQMNVGTRPINLEPIFQGYIDSLKRYLDGLTAERTSQNSELNN 256
+FLEQQN+VL+TKW LLQQ T NLEP+F+ Y+ L++ LD L ++ SEL
Sbjct: 230 QFLEQQNKVLETKWNLLQQQTTTTSSKNLEPLFETYLSVLRKQLDTLGNDKGRLQSELKT 289
Query: 257 MQDLVEDYKKKYEDEINKRTAAENDFVTLKKDVDNAYMIKVELQSKVDLLNQEIEFLKVL 316
MQD VED+K KYE+EINKRTAAENDFV LKKDVD AY+ KVEL++KVD LN EI FLKVL
Sbjct: 290 MQDSVEDFKTKYEEEINKRTAAENDFVVLKKDVDAAYLNKVELEAKVDSLNDEINFLKVL 349
Query: 317 YDAEISQIHQSVTDTNVILSMDNSRNLDLDSIIAEVKAQYEEIAQRSKEEAEALYHSKYE 376
YDAE+SQ+ V+DT+V+LSMDN+RNLDLDSIIAEV+AQYEEIAQRSK EAEALY +K +
Sbjct: 350 YDAELSQMQTHVSDTSVVLSMDNNRNLDLDSIIAEVRAQYEEIAQRSKAEAEALYQTKVQ 409
Query: 377 ELQVTVGRHGDSLKEIKIEISELNRVIQRLQGEIAHVKKQCKNVQDAIADAEQRGEHALK 436
+LQ++V +HGD+LK K EI+ELNR+IQRL+ EI ++KKQC+ +Q ++ADAEQRGE+ALK
Sbjct: 410 QLQISVDQHGDNLKNTKSEIAELNRMIQRLRAEIENIKKQCQTLQVSVADAEQRGENALK 469
Query: 437 DARNKLNDLEEALQQAKEDLARLLRDYQELMNVKLALDVEIATYRKLLEGEECRMSGDLS 496
DA +K +LE ALQQAKE+LAR+LR+YQELM+VKLALD+EIATYRKLLEGEE RMSG+
Sbjct: 470 DAHSKRVELEAALQQAKEELARMLREYQELMSVKLALDIEIATYRKLLEGEEYRMSGECQ 529
Query: 497 SNVTVSVTSSTISSNVASKAAFGGSGGRGSSSGGGYSSGSSSYGSGGRQSGSRGGSGGGG 556
S V++SV S + S+ G SGG GS SG G SSG +GSG SGS G G GG
Sbjct: 530 SAVSISVVSGSTSTG-------GISGGLGSGSGFGLSSG---FGSG---SGS--GFGFGG 574
Query: 557 SISG 560
S+SG
Sbjct: 575 SVSG 578
Score = 47.4 bits (111), Expect = 4e-05
Identities = 42/121 (34%), Positives = 58/121 (47%), Gaps = 19/121 (15%)
Query: 499 VTVSVTSSTISSNVASKAAFGGSGGRGSSSGGGYSSGSSSYGSGGRQS-GSRGGSGGGGS 557
VT + S++S+ + ++ G RG +S GS+ G G R + S SGG G
Sbjct: 62 VTSLIAPSSLSAAMIARQQCVRGGPRG------FSCGSAIVGGGKRGAFSSVSMSGGAGR 115
Query: 558 ISGGGYGSGG-----GSGGRYGSGGGSKGGSISGG--GYGSGGGKHSSGGGSRGGSSSGG 610
S GG+GS G+ S GS+ G+ GG G+G+GG GG GGS SG
Sbjct: 116 CSSGGFGSRSLYNLRGNKSISMSVAGSRQGACFGGAGGFGTGG-----FGGGFGGSFSGK 170
Query: 611 G 611
G
Sbjct: 171 G 171
Score = 43.5 bits (101), Expect = 6e-04
Identities = 34/92 (36%), Positives = 40/92 (43%), Gaps = 9/92 (9%)
Query: 545 QSGSRGGSGGGGSISGGGYGSGGGSGGRYGSGGGSKGGSISGGGYGSGGGK--HSSGGGS 602
+ G RG S G + GG G+ G+G S GG S Y G K S GS
Sbjct: 83 RGGPRGFSCGSAIVGGGKRGAFSSVSMSGGAGRCSSGGFGSRSLYNLRGNKSISMSVAGS 142
Query: 603 RGGSSSG-------GGYGSGGGGSSSVKGSSG 627
R G+ G GG+G G GGS S KG G
Sbjct: 143 RQGACFGGAGGFGTGGFGGGFGGSFSGKGGPG 174
Score = 32.7 bits (73), Expect = 1.1
Identities = 18/34 (52%), Positives = 18/34 (52%)
Query: 598 SGGGSRGGSSSGGGYGSGGGGSSSVKGSSGEAFG 631
SG S GG S G G GSG G SS SG FG
Sbjct: 538 SGSTSTGGISGGLGSGSGFGLSSGFGSGSGSGFG 571
>gi|153791158 keratin 75 [Homo sapiens]
Length = 551
Score = 575 bits (1483), Expect = e-164
Identities = 324/558 (58%), Positives = 387/558 (69%), Gaps = 39/558 (6%)
Query: 17 GGFRGFSSGSAVVSGGSRRSTSSFSCLSRHGGGGGGFG-----GGGFGSRSLVGLGGTKS 71
G RGFS+ SA+ R SS S ++R G GG G G FGSRSL LGG K
Sbjct: 12 GSRRGFSTTSAITPAAGRSRFSSVS-VARSAAGSGGLGRISSAGASFGSRSLYNLGGAKR 70
Query: 72 ISISVAGGGGGFGAAGGFGGRGGGFGGGSSFGGGSGFSGGGFGGGGFGGGRFGGFGGPGG 131
+SI+ G G GFGGR + FG SGF G+GGG GGF GP
Sbjct: 71 VSIN----GCGSSCRSGFGGRAS-----NRFGVNSGF--------GYGGGVGGGFSGPSF 113
Query: 132 VGGLGGPGGFGPGGYPGGIHEVSVNQSLLQPLNVKVDPEIQNVKAQEREQIKTLNNKFAS 191
P PGGI EV+VNQSLL PL++++DP IQ V+A+EREQIKTLNNKFAS
Sbjct: 114 -----------PVCPPGGIQEVTVNQSLLTPLHLQIDPTIQRVRAEEREQIKTLNNKFAS 162
Query: 192 FIDKVRFLEQQNQVLQTKWELLQQMNVGTRPINLEPIFQGYIDSLKRYLDGLTAERTSQN 251
FIDKVRFLEQQN+VL+TKW LLQ+ T NLEP+F Y L+R L+ +T ER
Sbjct: 163 FIDKVRFLEQQNKVLETKWALLQEQGSRTVRQNLEPLFDSYTSELRRQLESITTERGRLE 222
Query: 252 SELNNMQDLVEDYKKKYEDEINKRTAAENDFVTLKKDVDNAYMIKVELQSKVDLLNQEIE 311
+EL NMQD+VED+K +YEDEINKRTAAEN+FV LKKDVD AYM KVEL++KV L +EI
Sbjct: 223 AELRNMQDVVEDFKVRYEDEINKRTAAENEFVALKKDVDAAYMNKVELEAKVKSLPEEIN 282
Query: 312 FLKVLYDAEISQIHQSVTDTNVILSMDNSRNLDLDSIIAEVKAQYEEIAQRSKEEAEALY 371
F+ ++DAE+SQ+ V DT+V+LSMDN+RNLDLDSIIAEVKAQYE+IA RS+ EAE+ Y
Sbjct: 283 FIHSVFDAELSQLQTQVGDTSVVLSMDNNRNLDLDSIIAEVKAQYEDIANRSRAEAESWY 342
Query: 372 HSKYEELQVTVGRHGDSLKEIKIEISELNRVIQRLQGEIAHVKKQCKNVQDAIADAEQRG 431
+KYEELQVT GRHGD L+ K EISE+NR+IQRL+ EI VKKQC ++Q AIADAEQRG
Sbjct: 343 QTKYEELQVTAGRHGDDLRNTKQEISEMNRMIQRLRAEIDSVKKQCSSLQTAIADAEQRG 402
Query: 432 EHALKDARNKLNDLEEALQQAKEDLARLLRDYQELMNVKLALDVEIATYRKLLEGEECRM 491
E ALKDAR KL DLEEALQ+AK+D+ARLLR+YQELMN+KLALDVEIATYRKLLEGEECR+
Sbjct: 403 ELALKDARAKLVDLEEALQKAKQDMARLLREYQELMNIKLALDVEIATYRKLLEGEECRL 462
Query: 492 SGDLSSNVTVSVTSSTISSNVASKAAFGGSGGRGSSSGGGYSSGSSSYGSGGRQSGSRGG 551
SG+ S V +SV +ST+SS S ++ GG G G G GYS +S GG G+ G
Sbjct: 463 SGEGVSPVNISVVTSTLSSGYGSGSSIGG-GNLGLGGGSGYSFTTS----GGHSLGAGLG 517
Query: 552 SGGGGSISGGGYGSGGGS 569
G + S G G G S
Sbjct: 518 GSGFSATSNRGLGGSGSS 535
Score = 44.3 bits (103), Expect = 3e-04
Identities = 44/114 (38%), Positives = 56/114 (49%), Gaps = 20/114 (17%)
Query: 526 SSSGGGYSSGSSSYGSGGRQ-------SGSRGGSGGGGSISGGGYGSGGGSGGRYGSGGG 578
S S G+S+ S+ + GR + S GSGG G IS G + GS Y GG
Sbjct: 11 SGSRRGFSTTSAITPAAGRSRFSSVSVARSAAGSGGLGRISSAG--ASFGSRSLYNLGG- 67
Query: 579 SKGGSISGGGYG--SGGGKHSSGGGSRGGSSSGGGYGSGGGGSSSVKGSSGEAF 630
+K SI+G G SG G +S +R G +SG GYG G GG G SG +F
Sbjct: 68 AKRVSINGCGSSCRSGFGGRAS---NRFGVNSGFGYGGGVGG-----GFSGPSF 113
>gi|32567786 keratin 6L [Homo sapiens]
Length = 535
Score = 555 bits (1429), Expect = e-158
Identities = 319/553 (57%), Positives = 376/553 (67%), Gaps = 56/553 (10%)
Query: 21 GFSSGSAVVSGGSRRSTSSFSC-LSRHGGGGGGF----GGGGFGSRSLVGLGGTKSISIS 75
GFSS SA GS+ TS S +SR G GGG G GGFGSRSL LGG KSIS+S
Sbjct: 15 GFSSNSASGGSGSQARTSFSSVTVSRSSGSGGGAHCGPGTGGFGSRSLYNLGGHKSISVS 74
Query: 76 VAGGGGGFGAAGGFGGRGGGFGGGSSFGGGSGFSGGGFGGGGFGGGRFGGFGGPGGVGGL 135
VAGG G GG GFG F G G
Sbjct: 75 VAGG---------------------------ALLGRALGGFGFGSRAFMGQG-------- 99
Query: 136 GGPGGFGPGGYPGGIHEVSVNQSLLQPLNVKVDPEIQNVKAQEREQIKTLNNKFASFIDK 195
G FGP PGGI EV+VNQSLL PL+V++DPEIQ V+ QEREQIKTLNNKFASFIDK
Sbjct: 100 AGRQTFGPACPPGGIQEVTVNQSLLTPLHVEIDPEIQRVRTQEREQIKTLNNKFASFIDK 159
Query: 196 VRFLEQQNQVLQTKWELLQQ--MNVGTRPINLEPIFQGYIDSLKRYLDGLTAERTSQNSE 253
VRFLEQQN+VL+TKW LLQ+ N+G NLEP+F+ Y+ S++ LD L +ER +SE
Sbjct: 160 VRFLEQQNKVLETKWALLQEQGQNLGVTRNNLEPLFEAYLGSMRSTLDRLQSERGRLDSE 219
Query: 254 LNNMQDLVEDYKKKYEDEINKRTAAENDFVTLKKDVDNAYMIKVELQSKVDLLNQEIEFL 313
L N+QDLVED+K KYEDEINK TAAEN+FV LKKDVD AYM +++L KV L QEI+FL
Sbjct: 220 LRNVQDLVEDFKNKYEDEINKHTAAENEFVVLKKDVDAAYMGRMDLHGKVGTLTQEIDFL 279
Query: 314 KVLYDAEISQIHQSVTDTNVILSMDNSRNLDLDSIIAEVKAQYEEIAQRSKEEAEALYHS 373
+ LY+ E+SQ+ V++TNV+LSMDN+RNLDLDSIIAEVKAQYE IAQRS+ EAEA Y +
Sbjct: 280 QQLYEMELSQVQTHVSNTNVVLSMDNNRNLDLDSIIAEVKAQYELIAQRSRAEAEAWYQT 339
Query: 374 KYEELQVTVGRHGDSLKEIKIEISELNRVIQRLQGEIAHVKKQCKNVQDAIADAEQRGEH 433
KYEELQVT G+HGD+L++ K EI+EL R IQRLQGE KKQC+ +Q AIA+AEQRGE
Sbjct: 340 KYEELQVTAGKHGDNLRDTKNEIAELTRTIQRLQGEADAAKKQCQQLQTAIAEAEQRGEL 399
Query: 434 ALKDARNKLNDLEEALQQAKEDLARLLRDYQELMNVKLALDVEIATYRKLLEGEECRMSG 493
ALKDA+ KL DL+ AL QAKEDL RLLRDYQELMNVKLALDVEIATYRKLLE EE RMSG
Sbjct: 400 ALKDAQKKLGDLDVALHQAKEDLTRLLRDYQELMNVKLALDVEIATYRKLLESEESRMSG 459
Query: 494 DLSSNVTVSVTSSTISSNVASKAAFGGSGGRGSSSGGGYSSGSSSYGSGGRQSGSRGGSG 553
+ S V++SVT ++ + GG +S GGG S G GSGG G +
Sbjct: 460 ECPSAVSISVTGNSTTV----------CGGGAASFGGGISLG----GSGGATKGGFSTNV 505
Query: 554 GGGSISGGGYGSG 566
G ++ GG +G
Sbjct: 506 GYSTVKGGPVSAG 518
Score = 41.6 bits (96), Expect = 0.002
Identities = 33/92 (35%), Positives = 39/92 (42%), Gaps = 8/92 (8%)
Query: 527 SSGGGYSSGSSSYGSGGRQ-------SGSRGGSGGGGSISGGGYGSGGGSGGRYGSGGGS 579
S+ GG+SS S+S GSG + + SR GGG+ G G G G GS Y GG
Sbjct: 11 STKGGFSSNSASGGSGSQARTSFSSVTVSRSSGSGGGAHCGPGTG-GFGSRSLYNLGGHK 69
Query: 580 KGGSISGGGYGSGGGKHSSGGGSRGGSSSGGG 611
GG G G GSR G G
Sbjct: 70 SISVSVAGGALLGRALGGFGFGSRAFMGQGAG 101
Score = 36.6 bits (83), Expect = 0.073
Identities = 25/74 (33%), Positives = 29/74 (39%), Gaps = 2/74 (2%)
Query: 561 GGYGSGGGSGGRYGSGGGSKGGSISGGGYGSGGGKHSSGGGSRGGSSSGGGYGSGGGGSS 620
GG+ S SGG S GSGGG H G GG S Y GG S
Sbjct: 14 GGFSSNSASGGSGSQARTSFSSVTVSRSSGSGGGAHCGPG--TGGFGSRSLYNLGGHKSI 71
Query: 621 SVKGSSGEAFGSSV 634
SV + G G ++
Sbjct: 72 SVSVAGGALLGRAL 85
Score = 35.4 bits (80), Expect = 0.16
Identities = 29/79 (36%), Positives = 38/79 (48%), Gaps = 11/79 (13%)
Query: 8 KSRGRGGG---GGGFRGFSSGSAVVSGGSRRSTSSFSCLSRHGGG--GGGFGGGGFGSRS 62
+S G GGG G G GF S S GG + + S + GG G GG GFGSR+
Sbjct: 40 RSSGSGGGAHCGPGTGGFGSRSLYNLGGHKSISVSVA-----GGALLGRALGGFGFGSRA 94
Query: 63 LVGLG-GTKSISISVAGGG 80
+G G G ++ + GG
Sbjct: 95 FMGQGAGRQTFGPACPPGG 113
Score = 32.7 bits (73), Expect = 1.1
Identities = 22/58 (37%), Positives = 25/58 (43%), Gaps = 3/58 (5%)
Query: 573 YGSGGGSKGGSISGGGYGSGGGKHSSGGGSRGGSSSGG---GYGSGGGGSSSVKGSSG 627
Y + GG S SGG SS SR S GG G G+GG GS S+ G
Sbjct: 10 YSTKGGFSSNSASGGSGSQARTSFSSVTVSRSSGSGGGAHCGPGTGGFGSRSLYNLGG 67
>gi|28173564 keratin 73 [Homo sapiens]
Length = 540
Score = 546 bits (1408), Expect = e-155
Identities = 313/549 (57%), Positives = 390/549 (71%), Gaps = 53/549 (9%)
Query: 1 MSCQISCKSRGRGGGGGGFRGFSSGSAVVSGGSRRSTSSFSCLSRHGGGGGGFGGGGFGS 60
MS Q + KS GG FS SAV+SGGS S + GG G GG F S
Sbjct: 1 MSRQFTYKSGAAAKGG-----FSGCSAVLSGGSSSS---------YRAGGKGLSGG-FSS 45
Query: 61 RSLVGLGGTKSISISVAGGGGGFGAAGGFGGRGGGFGGGSSFGGGSGFSGGGFGGGGFGG 120
RSL LGG +SIS +VA G G AGG+ GFG G + SGF+G FG
Sbjct: 46 RSLYSLGGARSISFNVASGSGW---AGGY-----GFGRGRA----SGFAGSMFGSVAL-- 91
Query: 121 GRFGGFGGPGGVGGLGGPGGFGPGGYPGGIHEVSVNQSLLQPLNVKVDPEIQNVKAQERE 180
G V P PGGIH+V++N+SLL PLNV++DPEIQ V+AQERE
Sbjct: 92 ---------GSVCPSLCP--------PGGIHQVTINKSLLAPLNVELDPEIQKVRAQERE 134
Query: 181 QIKTLNNKFASFIDKVRFLEQQNQVLQTKWELLQQMNVGTRPINLEPIFQGYIDSLKRYL 240
QIK LNNKFASFIDKVRFLEQQNQVL+TKWELLQQ+++ NLEPI +GYI +L++ L
Sbjct: 135 QIKVLNNKFASFIDKVRFLEQQNQVLETKWELLQQLDLNNCKNNLEPILEGYISNLRKQL 194
Query: 241 DGLTAERTSQNSELNNMQDLVEDYKKKYEDEINKRTAAENDFVTLKKDVDNAYMIKVELQ 300
+ L+ +R +SEL +++++VEDYKK+YE+EINKRT AEN+FV LKKDVD AY KVELQ
Sbjct: 195 ETLSGDRVRLDSELRSVREVVEDYKKRYEEEINKRTTAENEFVVLKKDVDAAYTSKVELQ 254
Query: 301 SKVDLLNQEIEFLKVLYDAEISQIHQSVTDTNVILSMDNSRNLDLDSIIAEVKAQYEEIA 360
+KVD L+ EI+F K LY+ E +QI ++DT++ILSMDN+RNLDLDSIIAEV+AQYEEIA
Sbjct: 255 AKVDALDGEIKFFKCLYEGETAQIQSHISDTSIILSMDNNRNLDLDSIIAEVRAQYEEIA 314
Query: 361 QRSKEEAEALYHSKYEELQVTVGRHGDSLKEIKIEISELNRVIQRLQGEIAHVKKQCKNV 420
++SK EAEALY +K++ELQ+ GRHGD LK K EISEL R+IQRL+ EI VKKQC N+
Sbjct: 315 RKSKAEAEALYQTKFQELQLAAGRHGDDLKHTKNEISELTRLIQRLRSEIESVKKQCANL 374
Query: 421 QDAIADAEQRGEHALKDARNKLNDLEEALQQAKEDLARLLRDYQELMNVKLALDVEIATY 480
+ AIADAEQRG+ ALKDAR KL++LE ALQQAKE+LAR+LR+YQEL++VKL+LD+EIATY
Sbjct: 375 ETAIADAEQRGDCALKDARAKLDELEGALQQAKEELARMLREYQELLSVKLSLDIEIATY 434
Query: 481 RKLLEGEECRMSGDLSSNVTVSVTSSTISSNVASKAAFGGS-----GGRGSSSGGGYS-- 533
RKLLEGEECRMSG+ +++V++SV +S+++ + A FG S G SS GGYS
Sbjct: 435 RKLLEGEECRMSGEYTNSVSISVINSSMAGMAGTGAGFGFSNAGTYGYWPSSVSGGYSML 494
Query: 534 SGSSSYGSG 542
G GSG
Sbjct: 495 PGGCVTGSG 503
Score = 47.8 bits (112), Expect = 3e-05
Identities = 32/89 (35%), Positives = 37/89 (41%), Gaps = 3/89 (3%)
Query: 544 RQSGSRGGSGGGGSISGGGYGSGGGSGGRYGSGGGSKGGSISGGGYGSGGGKHSSGGGSR 603
RQ + G+ G SG GGS Y +GG G S S GG S
Sbjct: 3 RQFTYKSGAAAKGGFSGCSAVLSGGSSSSYRAGGKGLSGGFSSRSLYSLGGARSISFNVA 62
Query: 604 GGSSSGGGYGSGGGGSSSVKGSSGEAFGS 632
GS GGYG G G +S G +G FGS
Sbjct: 63 SGSGWAGGYGFGRGRAS---GFAGSMFGS 88
Score = 40.0 bits (92), Expect = 0.007
Identities = 35/92 (38%), Positives = 41/92 (44%), Gaps = 16/92 (17%)
Query: 507 TISSNVASKAAFGG-----SGGRGSS---SGGGYSSGSSS---YGSGGRQSGSRGGSGGG 555
T S A+K F G SGG SS G G S G SS Y GG +S S + G
Sbjct: 6 TYKSGAAAKGGFSGCSAVLSGGSSSSYRAGGKGLSGGFSSRSLYSLGGARSISFNVASGS 65
Query: 556 GSISGGGYGSGGGSGGRYGSGGGSKGGSISGG 587
G G G+G G SG GS GS++ G
Sbjct: 66 GWAGGYGFGRGRASG-----FAGSMFGSVALG 92
Score = 38.5 bits (88), Expect = 0.019
Identities = 33/90 (36%), Positives = 41/90 (45%), Gaps = 11/90 (12%)
Query: 525 GSSSGGGYSSGSSSYGSGGRQS----GSRGGSGGGGSISGGGYGSGGGSGGRYGSGGGSK 580
G+++ GG+S G S+ SGG S G +G SGG S S G SG G
Sbjct: 10 GAAAKGGFS-GCSAVLSGGSSSSYRAGGKGLSGGFSSRSLYSLGGARSISFNVASGSG-- 66
Query: 581 GGSISGGGYGSGGGKHSSGGGSRGGSSSGG 610
GGYG G G+ S GS GS + G
Sbjct: 67 ----WAGGYGFGRGRASGFAGSMFGSVALG 92
Score = 34.3 bits (77), Expect = 0.36
Identities = 24/67 (35%), Positives = 27/67 (40%), Gaps = 3/67 (4%)
Query: 573 YGSGGGSKGGSISGGGYGSGGGKHS---SGGGSRGGSSSGGGYGSGGGGSSSVKGSSGEA 629
Y SG +KGG SGG S G G GG SS Y GG S S +SG
Sbjct: 7 YKSGAAAKGGFSGCSAVLSGGSSSSYRAGGKGLSGGFSSRSLYSLGGARSISFNVASGSG 66
Query: 630 FGSSVTF 636
+ F
Sbjct: 67 WAGGYGF 73
>gi|15618995 keratin 71 [Homo sapiens]
Length = 523
Score = 536 bits (1382), Expect = e-152
Identities = 314/563 (55%), Positives = 392/563 (69%), Gaps = 52/563 (9%)
Query: 1 MSCQISCKSRGRGGGGGGFRGFSSGSAVVSGGSRRSTSSFSCLSRHGGGGGGFGGGGFGS 60
MS Q +CKS GG FS SAV+SGGS +SSF G G GG FGS
Sbjct: 1 MSRQFTCKSGAAAKGG-----FSGCSAVLSGGS---SSSFRA------GSKGLSGG-FGS 45
Query: 61 RSLVGLGGTKSISISVAGGGGGFGAAGGFGGRGGGFGGGSSFGGGSGFSGGGFGGGGFGG 120
RSL LGG + S++VA G G +GG+ GFG G + SGF+G FG G
Sbjct: 46 RSLYSLGGVR--SLNVAS---GSGKSGGY-----GFGRGRA----SGFAGSMFGSVALGP 91
Query: 121 GRFGGFGGPGGVGGLGGPGGFGPGGYPGGIHEVSVNQSLLQPLNVKVDPEIQNVKAQERE 180
V P PGGIH+V+VN+SLL PLNV++DPEIQ V+AQERE
Sbjct: 92 -----------VCPTVCP--------PGGIHQVTVNESLLAPLNVELDPEIQKVRAQERE 132
Query: 181 QIKTLNNKFASFIDKVRFLEQQNQVLQTKWELLQQMNVGTRPINLEPIFQGYIDSLKRYL 240
QIK LNNKFASFIDKVRFLEQQNQVL+TKWELLQQ+++ NLEPI +GYI +L++ L
Sbjct: 133 QIKALNNKFASFIDKVRFLEQQNQVLETKWELLQQLDLNNCKNNLEPILEGYISNLRKQL 192
Query: 241 DGLTAERTSQNSELNNMQDLVEDYKKKYEDEINKRTAAENDFVTLKKDVDNAYMIKVELQ 300
+ L+ +R +SEL N++D+VEDYKK+YE+EINKRTAAEN+FV LKKDVD AY KVELQ
Sbjct: 193 ETLSGDRVRLDSELRNVRDVVEDYKKRYEEEINKRTAAENEFVLLKKDVDAAYANKVELQ 252
Query: 301 SKVDLLNQEIEFLKVLYDAEISQIHQSVTDTNVILSMDNSRNLDLDSIIAEVKAQYEEIA 360
+KV+ ++QEI+F + L++AEI+QI ++D +VILSMDN+RNLDLDSII EV+ QYEEIA
Sbjct: 253 AKVESMDQEIKFFRCLFEAEITQIQSHISDMSVILSMDNNRNLDLDSIIDEVRTQYEEIA 312
Query: 361 QRSKEEAEALYHSKYEELQVTVGRHGDSLKEIKIEISELNRVIQRLQGEIAHVKKQCKNV 420
+SK EAEALY +K++ELQ+ GRHGD LK K EISEL R+IQR++ EI +VKKQ N+
Sbjct: 313 LKSKAEAEALYQTKFQELQLAAGRHGDDLKNTKNEISELTRLIQRIRSEIENVKKQASNL 372
Query: 421 QDAIADAEQRGEHALKDARNKLNDLEEALQQAKEDLARLLRDYQELMNVKLALDVEIATY 480
+ AIADAEQRG++ALKDAR KL++LE AL QAKE+LAR+LR+YQELM++KLALD+EIATY
Sbjct: 373 ETAIADAEQRGDNALKDARAKLDELEGALHQAKEELARMLREYQELMSLKLALDMEIATY 432
Query: 481 RKLLEGEECRMSGDLSSNVTVSVTSSTISSNVASKAAFGGSGGRGSSSGGGYSSGSSSYG 540
RKLLE EECRMSG+ S V++S+ SST +V SGG ++S S S G
Sbjct: 433 RKLLESEECRMSGEFPSPVSISIISSTSGGSVYGFRPSMVSGGYVANSSNCISGVCSVRG 492
Query: 541 SGGRQSGS----RGGSGGGGSIS 559
GR GS + G G S+S
Sbjct: 493 GEGRSRGSANDYKDTLGKGSSLS 515
Score = 43.9 bits (102), Expect = 5e-04
Identities = 37/90 (41%), Positives = 45/90 (50%), Gaps = 13/90 (14%)
Query: 525 GSSSGGGYSSGSSSYGSGGRQS----GSRGGSGGGGSISGGGYGSGGGSGGRYGSGGGSK 580
G+++ GG+S G S+ SGG S GS+G SGG GS S Y GG SG G
Sbjct: 10 GAAAKGGFS-GCSAVLSGGSSSSFRAGSKGLSGGFGSRS--LYSLGGVRSLNVASGSG-- 64
Query: 581 GGSISGGGYGSGGGKHSSGGGSRGGSSSGG 610
GGYG G G+ S GS GS + G
Sbjct: 65 ----KSGGYGFGRGRASGFAGSMFGSVALG 90
Score = 41.2 bits (95), Expect = 0.003
Identities = 30/89 (33%), Positives = 36/89 (40%), Gaps = 5/89 (5%)
Query: 544 RQSGSRGGSGGGGSISGGGYGSGGGSGGRYGSGGGSKGGSISGGGYGSGGGKHSSGGGSR 603
RQ + G+ G SG GGS + +G G S GG S S
Sbjct: 3 RQFTCKSGAAAKGGFSGCSAVLSGGSSSSFRAGSKGLSGGFGSRSLYSLGGVRSLNVAS- 61
Query: 604 GGSSSGGGYGSGGGGSSSVKGSSGEAFGS 632
GS GGYG G G +S G +G FGS
Sbjct: 62 -GSGKSGGYGFGRGRAS---GFAGSMFGS 86
>gi|148612803 keratin 6 irs4 [Homo sapiens]
Length = 529
Score = 529 bits (1362), Expect = e-150
Identities = 305/556 (54%), Positives = 386/556 (69%), Gaps = 43/556 (7%)
Query: 1 MSCQISCKSRGRGGGGGGFRGFSSGSAVVSGGSRRSTSSFSCLSRHGGGGGGFGGGGFGS 60
MS Q++ KS G G FS SAVV R++ S + G G G GFGS
Sbjct: 1 MSRQLNIKSSGDKGN------FSVHSAVVP---RKAVGSLASYCAAGRGAGA----GFGS 47
Query: 61 RSLVGLGGTKSISISVAGGGGGFGAAGGFGGR-GGGFGGGSSFGGGSGFSGGGFGGGGFG 119
RSL LGG + IS +VAGGG AGG+G R G G+GGG + SGF+G FG G
Sbjct: 48 RSLYSLGGNRRISFNVAGGG---VRAGGYGFRPGSGYGGGRA----SGFAGSMFGSVALG 100
Query: 120 GGRFGGFGGPGGVGGLGGPGGFGPGGYPGGIHEVSVNQSLLQPLNVKVDPEIQNVKAQER 179
PGGIH+V+VN+SLL PLNV++DPEIQ V+AQER
Sbjct: 101 PACLSVCP-------------------PGGIHQVTVNKSLLAPLNVELDPEIQKVRAQER 141
Query: 180 EQIKTLNNKFASFIDKVRFLEQQNQVLQTKWELLQQMNVGTRPINLEPIFQGYIDSLKRY 239
EQIK LN+KFASFIDKVRFLEQQNQVL+TKWELLQQ+++ NLEPI +GYI +L++
Sbjct: 142 EQIKVLNDKFASFIDKVRFLEQQNQVLETKWELLQQLDLNNCKKNLEPILEGYISNLRKQ 201
Query: 240 LDGLTAERTSQNSELNNMQDLVEDYKKKYEDEINKRTAAENDFVTLKKDVDNAYMIKVEL 299
L+ L+ +R +SEL +M+DLVEDYKK+YE EIN+RT AEN+FV LKKD D AY +KVEL
Sbjct: 202 LETLSGDRVRLDSELRSMRDLVEDYKKRYEVEINRRTTAENEFVVLKKDADAAYAVKVEL 261
Query: 300 QSKVDLLNQEIEFLKVLYDAEISQIHQSVTDTNVILSMDNSRNLDLDSIIAEVKAQYEEI 359
Q+KVD L++EI+FLK LYDAEI+QI ++T+VILSMDN+R+LDLDSIIAEV+ YEEI
Sbjct: 262 QAKVDSLDKEIKFLKCLYDAEIAQIQTHASETSVILSMDNNRDLDLDSIIAEVRMHYEEI 321
Query: 360 AQRSKEEAEALYHSKYEELQVTVGRHGDSLKEIKIEISELNRVIQRLQGEIAHVKKQCKN 419
A +SK EAEALY +K +ELQ+ RHGD LK + E+ ELNR+IQR++ EI +VKKQ +
Sbjct: 322 ALKSKAEAEALYQTKIQELQLAASRHGDDLKHTRSEMVELNRLIQRIRCEIGNVKKQRAS 381
Query: 420 VQDAIADAEQRGEHALKDARNKLNDLEEALQQAKEDLARLLRDYQELMNVKLALDVEIAT 479
++ AIADAEQRG++ALKDA+ KL++LE AL QAKE+LAR+LR+YQELM++KLALD+EIAT
Sbjct: 382 LETAIADAEQRGDNALKDAQAKLDELEGALHQAKEELARMLREYQELMSLKLALDMEIAT 441
Query: 480 YRKLLEGEECRMSGDLSSNVTVSVTSSTISSNVASKAA---FGGSGGRGSSSGGGYSSGS 536
YRKLLEGEECRMSG+ S+V++SV SS+ S +A G S GSS
Sbjct: 442 YRKLLEGEECRMSGENPSSVSISVISSSSYSYHHPSSAGVDLGASAVAGSSGSTQSGQTK 501
Query: 537 SSYGSGGRQSGSRGGS 552
++ GG ++G S
Sbjct: 502 TTEARGGDLKDTQGKS 517
Score = 39.3 bits (90), Expect = 0.011
Identities = 27/70 (38%), Positives = 34/70 (48%), Gaps = 7/70 (10%)
Query: 551 GSGGGGSISGGGYGSGGGSGGRYGSGGGSK-GGSISGGGYGSGGGKHSSGGGSRGGSSSG 609
GS +G G G+G GS Y GG + +++GGG +GG G R GS G
Sbjct: 29 GSLASYCAAGRGAGAGFGSRSLYSLGGNRRISFNVAGGGVRAGGY------GFRPGSGYG 82
Query: 610 GGYGSGGGGS 619
GG SG GS
Sbjct: 83 GGRASGFAGS 92
Score = 37.7 bits (86), Expect = 0.033
Identities = 33/103 (32%), Positives = 46/103 (44%), Gaps = 15/103 (14%)
Query: 490 RMSGDLSSNVTVSVTSSTISSNVASKAAFGGSGGRGSSSGGGYSSGSSSYGSGGRQSGSR 549
+ SGD + SV S+ + A + GRG+ +G G S Y GG + S
Sbjct: 8 KSSGDKGN---FSVHSAVVPRKAVGSLASYCAAGRGAGAGFG---SRSLYSLGGNRRISF 61
Query: 550 GGSGGGGSISGGGYGSGGGSGGRYGSG-GGSKGGSISGGGYGS 591
+GGG + GGYG R GSG GG + +G +GS
Sbjct: 62 NVAGGG--VRAGGYGF------RPGSGYGGGRASGFAGSMFGS 96
Score = 32.7 bits (73), Expect = 1.1
Identities = 30/92 (32%), Positives = 37/92 (40%), Gaps = 11/92 (11%)
Query: 496 SSNVTVSVTSSTISSNVASKAAFGGSGGRGSSSGGGYSSGSSSYGSGGRQSGSRGGSGGG 555
S+ V S S A + A G G R S GG S + GG + +GG
Sbjct: 20 SAVVPRKAVGSLASYCAAGRGAGAGFGSRSLYSLGGNRRISFNVAGGGVR------AGGY 73
Query: 556 GSISGGGYGSGGGSGGRYGSGGGSKGGSISGG 587
G G GYG GGR GS GS++ G
Sbjct: 74 GFRPGSGYG-----GGRASGFAGSMFGSVALG 100
Score = 31.6 bits (70), Expect = 2.3
Identities = 23/60 (38%), Positives = 27/60 (45%), Gaps = 12/60 (20%)
Query: 585 SGGGYGSGGGKHS--SGGGSR-------GGSSSGGGYG---SGGGGSSSVKGSSGEAFGS 632
+G G G+G G S S GG+R GG GGYG G G G +G FGS
Sbjct: 37 AGRGAGAGFGSRSLYSLGGNRRISFNVAGGGVRAGGYGFRPGSGYGGGRASGFAGSMFGS 96
>gi|28372503 keratin 72 isoform 1 [Homo sapiens]
Length = 511
Score = 525 bits (1353), Expect = e-149
Identities = 298/537 (55%), Positives = 373/537 (69%), Gaps = 66/537 (12%)
Query: 21 GFSSGSAVVSGGSRRSTSSFSCLSRHGGGGGGFGGGGFGSRSLVGLGGTKSISISVAGGG 80
GFS SAV+SGG S++SF + G FGS+SL LGG++S+++S A
Sbjct: 15 GFSGCSAVLSGGIGSSSASFRARVK--------GSASFGSKSLSCLGGSRSLALSAAARR 66
Query: 81 GGFGAAGGFGGRGGGFGGGSSFGGGSGFSGGGFGGGGFGGGRFGGFGGPGGVGGLGGPGG 140
G GGR GGF VG G G
Sbjct: 67 G--------------------------------------GGRLGGF-----VGTAFGSAG 83
Query: 141 FGPGGY----PGGIHEVSVNQSLLQPLNVKVDPEIQNVKAQEREQIKTLNNKFASFIDKV 196
GP PGGI +V+VN+SLL PLNV++DPEIQ V+AQEREQIK LNNKFASFIDKV
Sbjct: 84 LGPKCPSVCPPGGIPQVTVNKSLLAPLNVEMDPEIQRVRAQEREQIKALNNKFASFIDKV 143
Query: 197 RFLEQQNQVLQTKWELLQQMNVGTRPINLEPIFQGYIDSLKRYLDGLTAERTSQNSELNN 256
RFLEQQNQVL+TKW LLQQ+++ NLEPI++GYI +L++ L+ L+ + +SEL N
Sbjct: 144 RFLEQQNQVLETKWNLLQQLDLNNCRKNLEPIYEGYISNLQKQLEMLSGDGVRLDSELRN 203
Query: 257 MQDLVEDYKKKYEDEINKRTAAENDFVTLKKDVDNAYMIKVELQSKVDLLNQEIEFLKVL 316
MQDLVEDYKK+YE EIN+RTAAEN+FV LKKDVD AYM KVELQ+KVD L EI+F K L
Sbjct: 204 MQDLVEDYKKRYEVEINRRTAAENEFVVLKKDVDAAYMNKVELQAKVDSLTDEIKFFKCL 263
Query: 317 YDAEISQIHQSVTDTNVILSMDNSRNLDLDSIIAEVKAQYEEIAQRSKEEAEALYHSKYE 376
Y+ EI+QI ++DT+++LSMDN+R+LDLDSIIAEV+AQYEEIA +SK EAE LY +K +
Sbjct: 264 YEGEITQIQSHISDTSIVLSMDNNRDLDLDSIIAEVRAQYEEIALKSKAEAETLYQTKIQ 323
Query: 377 ELQVTVGRHGDSLKEIKIEISELNRVIQRLQGEIAHVKKQCKNVQDAIADAEQRGEHALK 436
ELQVT G+HGD LK K EISELNR+IQR++ EI +VKKQC +++ AIADAEQRG+ ALK
Sbjct: 324 ELQVTAGQHGDDLKLTKAEISELNRLIQRIRSEIGNVKKQCADLETAIADAEQRGDCALK 383
Query: 437 DARNKLNDLEEALQQAKEDLARLLRDYQELMNVKLALDVEIATYRKLLEGEECRMSGDLS 496
DAR KL++LE AL QAKE+LAR+LR+YQEL+++KLALD+EIATYRKLLE EECRMSG+
Sbjct: 384 DARAKLDELEGALHQAKEELARMLREYQELVSLKLALDMEIATYRKLLESEECRMSGEYP 443
Query: 497 SNVTVSVTSSTISSNVASKAAFGGSGGRGSSSGGGYSSGSSSYGSGGRQSGSRGGSG 553
++V++SV SST + G+GG G S G G SS S SY + ++G G
Sbjct: 444 NSVSISVISSTNA----------GAGGAGFSMGFGASS-SYSYKTAAADVKTKGSCG 489
Score = 32.7 bits (73), Expect = 1.1
Identities = 25/75 (33%), Positives = 29/75 (38%), Gaps = 3/75 (4%)
Query: 547 GSRGGSGGGGSISGGGYGSGGGSGGRYGSGG---GSKGGSISGGGYGSGGGKHSSGGGSR 603
G R G G ++ GG GS S G GSK S GG + GG R
Sbjct: 11 GERLGFSGCSAVLSGGIGSSSASFRARVKGSASFGSKSLSCLGGSRSLALSAAARRGGGR 70
Query: 604 GGSSSGGGYGSGGGG 618
G G +GS G G
Sbjct: 71 LGGFVGTAFGSAGLG 85
>gi|226246663 keratin 72 isoform 1 [Homo sapiens]
Length = 511
Score = 525 bits (1353), Expect = e-149
Identities = 298/537 (55%), Positives = 373/537 (69%), Gaps = 66/537 (12%)
Query: 21 GFSSGSAVVSGGSRRSTSSFSCLSRHGGGGGGFGGGGFGSRSLVGLGGTKSISISVAGGG 80
GFS SAV+SGG S++SF + G FGS+SL LGG++S+++S A
Sbjct: 15 GFSGCSAVLSGGIGSSSASFRARVK--------GSASFGSKSLSCLGGSRSLALSAAARR 66
Query: 81 GGFGAAGGFGGRGGGFGGGSSFGGGSGFSGGGFGGGGFGGGRFGGFGGPGGVGGLGGPGG 140
G GGR GGF VG G G
Sbjct: 67 G--------------------------------------GGRLGGF-----VGTAFGSAG 83
Query: 141 FGPGGY----PGGIHEVSVNQSLLQPLNVKVDPEIQNVKAQEREQIKTLNNKFASFIDKV 196
GP PGGI +V+VN+SLL PLNV++DPEIQ V+AQEREQIK LNNKFASFIDKV
Sbjct: 84 LGPKCPSVCPPGGIPQVTVNKSLLAPLNVEMDPEIQRVRAQEREQIKALNNKFASFIDKV 143
Query: 197 RFLEQQNQVLQTKWELLQQMNVGTRPINLEPIFQGYIDSLKRYLDGLTAERTSQNSELNN 256
RFLEQQNQVL+TKW LLQQ+++ NLEPI++GYI +L++ L+ L+ + +SEL N
Sbjct: 144 RFLEQQNQVLETKWNLLQQLDLNNCRKNLEPIYEGYISNLQKQLEMLSGDGVRLDSELRN 203
Query: 257 MQDLVEDYKKKYEDEINKRTAAENDFVTLKKDVDNAYMIKVELQSKVDLLNQEIEFLKVL 316
MQDLVEDYKK+YE EIN+RTAAEN+FV LKKDVD AYM KVELQ+KVD L EI+F K L
Sbjct: 204 MQDLVEDYKKRYEVEINRRTAAENEFVVLKKDVDAAYMNKVELQAKVDSLTDEIKFFKCL 263
Query: 317 YDAEISQIHQSVTDTNVILSMDNSRNLDLDSIIAEVKAQYEEIAQRSKEEAEALYHSKYE 376
Y+ EI+QI ++DT+++LSMDN+R+LDLDSIIAEV+AQYEEIA +SK EAE LY +K +
Sbjct: 264 YEGEITQIQSHISDTSIVLSMDNNRDLDLDSIIAEVRAQYEEIALKSKAEAETLYQTKIQ 323
Query: 377 ELQVTVGRHGDSLKEIKIEISELNRVIQRLQGEIAHVKKQCKNVQDAIADAEQRGEHALK 436
ELQVT G+HGD LK K EISELNR+IQR++ EI +VKKQC +++ AIADAEQRG+ ALK
Sbjct: 324 ELQVTAGQHGDDLKLTKAEISELNRLIQRIRSEIGNVKKQCADLETAIADAEQRGDCALK 383
Query: 437 DARNKLNDLEEALQQAKEDLARLLRDYQELMNVKLALDVEIATYRKLLEGEECRMSGDLS 496
DAR KL++LE AL QAKE+LAR+LR+YQEL+++KLALD+EIATYRKLLE EECRMSG+
Sbjct: 384 DARAKLDELEGALHQAKEELARMLREYQELVSLKLALDMEIATYRKLLESEECRMSGEYP 443
Query: 497 SNVTVSVTSSTISSNVASKAAFGGSGGRGSSSGGGYSSGSSSYGSGGRQSGSRGGSG 553
++V++SV SST + G+GG G S G G SS S SY + ++G G
Sbjct: 444 NSVSISVISSTNA----------GAGGAGFSMGFGASS-SYSYKTAAADVKTKGSCG 489
Score = 32.7 bits (73), Expect = 1.1
Identities = 25/75 (33%), Positives = 29/75 (38%), Gaps = 3/75 (4%)
Query: 547 GSRGGSGGGGSISGGGYGSGGGSGGRYGSGG---GSKGGSISGGGYGSGGGKHSSGGGSR 603
G R G G ++ GG GS S G GSK S GG + GG R
Sbjct: 11 GERLGFSGCSAVLSGGIGSSSASFRARVKGSASFGSKSLSCLGGSRSLALSAAARRGGGR 70
Query: 604 GGSSSGGGYGSGGGG 618
G G +GS G G
Sbjct: 71 LGGFVGTAFGSAGLG 85
>gi|4504919 keratin 8 [Homo sapiens]
Length = 483
Score = 454 bits (1167), Expect = e-127
Identities = 252/453 (55%), Positives = 318/453 (70%), Gaps = 26/453 (5%)
Query: 103 GGGSGFSGGGF---GGGGFGGGRFGGFGGPGGVGGLGGPGGFGPGGYPGGIHEVSVNQSL 159
G GS S F G F GG GG+GG G+GG I V+VNQSL
Sbjct: 28 GPGSRISSSSFSRVGSSNFRGGLGGGYGGASGMGG---------------ITAVTVNQSL 72
Query: 160 LQPLNVKVDPEIQNVKAQEREQIKTLNNKFASFIDKVRFLEQQNQVLQTKWELLQQMNVG 219
L PL ++VDP IQ V+ QE+EQIKTLNNKFASFIDKVRFLEQQN++L+TKW LLQQ
Sbjct: 73 LSPLVLEVDPNIQAVRTQEKEQIKTLNNKFASFIDKVRFLEQQNKMLETKWSLLQQQK-- 130
Query: 220 TRPINLEPIFQGYIDSLKRYLDGLTAERTSQNSELNNMQDLVEDYKKKYEDEINKRTAAE 279
T N++ +F+ YI++L+R L+ L E+ +EL NMQ LVED+K KYEDEINKRT E
Sbjct: 131 TARSNMDNMFESYINNLRRQLETLGQEKLKLEAELGNMQGLVEDFKNKYEDEINKRTEME 190
Query: 280 NDFVTLKKDVDNAYMIKVELQSKVDLLNQEIEFLKVLYDAEISQIHQSVTDTNVILSMDN 339
N+FV +KKDVD AYM KVEL+S+++ L EI FL+ LY+ EI ++ ++DT+V+LSMDN
Sbjct: 191 NEFVLIKKDVDEAYMNKVELESRLEGLTDEINFLRQLYEEEIRELQSQISDTSVVLSMDN 250
Query: 340 SRNLDLDSIIAEVKAQYEEIAQRSKEEAEALYHSKYEELQVTVGRHGDSLKEIKIEISEL 399
SR+LD+DSIIAEVKAQYE+IA RS+ EAE++Y KYEELQ G+HGD L+ K EISE+
Sbjct: 251 SRSLDMDSIIAEVKAQYEDIANRSRAEAESMYQIKYEELQSLAGKHGDDLRRTKTEISEM 310
Query: 400 NRVIQRLQGEIAHVKKQCKNVQDAIADAEQRGEHALKDARNKLNDLEEALQQAKEDLARL 459
NR I RLQ EI +K Q +++ AIADAEQRGE A+KDA KL++LE ALQ+AK+D+AR
Sbjct: 311 NRNISRLQAEIEGLKGQRASLEAAIADAEQRGELAIKDANAKLSELEAALQRAKQDMARQ 370
Query: 460 LRDYQELMNVKLALDVEIATYRKLLEGEECRMSGDLSSNVTVSVTSSTISSNVASKAAFG 519
LR+YQELMNVKLALD+EIATYRKLLEGEE R+ + + + T+S + ++S A+G
Sbjct: 371 LREYQELMNVKLALDIEIATYRKLLEGEESRLESGMQNMSIHTKTTSGYAGGLSS--AYG 428
Query: 520 GSGGRGSSSGGGYSSGSSSYGSGGRQSGSRGGS 552
G +S G YS GSS G S SR S
Sbjct: 429 GL----TSPGLSYSLGSSFGSGAGSSSFSRTSS 457
Score = 37.4 bits (85), Expect = 0.043
Identities = 24/61 (39%), Positives = 33/61 (54%), Gaps = 10/61 (16%)
Query: 18 GFRGFSSGSAVVSGGSRRSTSSFSCLSR---HGGGGGGFGGGGFGSRSLVGLGGTKSISI 74
G R FSS S GSR S+SSFS + GG GGG+GG G+GG ++++
Sbjct: 16 GPRAFSSRSYTSGPGSRISSSSFSRVGSSNFRGGLGGGYGGAS-------GMGGITAVTV 68
Query: 75 S 75
+
Sbjct: 69 N 69
Score = 32.0 bits (71), Expect = 1.8
Identities = 24/69 (34%), Positives = 32/69 (46%), Gaps = 7/69 (10%)
Query: 499 VTVSVTSSTISSNVASKAAFGGSGGRGSSSGGGYSSGSSSYGSGGRQSGSRGGSGGGGSI 558
+++ VT + + + AF R +SG G SSS+ G S RGG GGG
Sbjct: 1 MSIRVTQKSYKVSTSGPRAFSS---RSYTSGPGSRISSSSFSRVG-SSNFRGGLGGG--- 53
Query: 559 SGGGYGSGG 567
GG G GG
Sbjct: 54 YGGASGMGG 62
Score = 31.6 bits (70), Expect = 2.3
Identities = 21/48 (43%), Positives = 23/48 (47%), Gaps = 1/48 (2%)
Query: 541 SGGRQSGSRGGSGGGGS-ISGGGYGSGGGSGGRYGSGGGSKGGSISGG 587
SG R SR + G GS IS + G S R G GGG G S GG
Sbjct: 15 SGPRAFSSRSYTSGPGSRISSSSFSRVGSSNFRGGLGGGYGGASGMGG 62
Score = 30.0 bits (66), Expect = 6.8
Identities = 21/54 (38%), Positives = 28/54 (51%), Gaps = 2/54 (3%)
Query: 583 SISGGGYGSG-GGKHSSGGGSRGGSSS-GGGYGSGGGGSSSVKGSSGEAFGSSV 634
+ S Y SG G + SS SR GSS+ GG G G GG+S + G + S+
Sbjct: 19 AFSSRSYTSGPGSRISSSSFSRVGSSNFRGGLGGGYGGASGMGGITAVTVNQSL 72
>gi|15431316 keratin, hair, basic, 4 [Homo sapiens]
Length = 600
Score = 444 bits (1141), Expect = e-124
Identities = 276/565 (48%), Positives = 358/565 (63%), Gaps = 35/565 (6%)
Query: 5 ISCKSRGRGGGGGGFRGFSSGSAVVSGGSRR-STSSFSCLSRHGGGGGGFGG-GGFGSRS 62
+SC+S R G FSS SA+ R +S SC S G GF G G FGSRS
Sbjct: 1 MSCRSY-RVSSGHRVGNFSSCSAMTPQNLNRFRANSVSCWS-----GPGFRGLGSFGSRS 54
Query: 63 LVGLGGTKSISISVAGG-----GGGFGAAGGFG---GRGGGFGGGSSFGGGSGFSGGGFG 114
++ G + S I+ G G FGA G G GRG G G + G GF G
Sbjct: 55 VITFG-SYSPRIAAVGSRPIHCGVRFGAGCGMGFGDGRGVGLGPRADSCVGLGFGAGSGI 113
Query: 115 GGGFGGGRFGGFGGPGGVGGLGGPGGFGPGGYPGGIHEVSVNQSLLQPLNVKVDPEIQNV 174
G GFGG FG VGG+G P I V+VN+SLL PLN+++DP Q V
Sbjct: 114 GYGFGGPGFGY-----RVGGVGVPAA-------PSITAVTVNKSLLTPLNLEIDPNAQRV 161
Query: 175 KAQEREQIKTLNNKFASFIDKVRFLEQQNQVLQTKWELLQQMNVGTRPINLEPIFQGYID 234
K E+EQIKTLNNKFASFIDKVRFLEQQN++L+TKW LQ+ NLEP+F+ YI
Sbjct: 162 KKDEKEQIKTLNNKFASFIDKVRFLEQQNKLLETKWSFLQEQKCIRS--NLEPLFESYIT 219
Query: 235 SLKRYLDGLTAERTSQNSELNNMQDLVEDYKKKYEDEINKRTAAENDFVTLKKDVDNAYM 294
+L+R L+ L +++ +E N++QD++E +KKKYE+E+ R AEN+FV LKKDVD A+M
Sbjct: 220 NLRRQLEVLVSDQARLQAERNHLQDVLEGFKKKYEEEVVCRANAENEFVALKKDVDAAFM 279
Query: 295 IKVELQSKVDLLNQEIEFLKVLYDAEISQIHQSVTDTNVILSMDNSRNLDLDSIIAEVKA 354
K +L++ VD L QEI+FLK LY EI + +++T+VI+ MDNSR+L+LD IIAEVKA
Sbjct: 280 NKSDLEANVDTLTQEIDFLKTLYMEEIQLLQSHISETSVIVKMDNSRDLNLDGIIAEVKA 339
Query: 355 QYEEIAQRSKEEAEALYHSKYEELQVTVGRHGDSLKEIKIEISELNRVIQRLQGEIAHVK 414
QYEE+A+RS+ +AEA Y +KYEE+QVT G+H D+L+ I+ EI+EL R+IQRL+ EI H K
Sbjct: 340 QYEEVARRSRADAEAWYQTKYEEMQVTAGQHCDNLRNIRNEINELTRLIQRLKAEIEHAK 399
Query: 415 KQCKNVQDAIADAEQRGEHALKDARNKLNDLEEALQQAKEDLARLLRDYQELMNVKLALD 474
Q ++ A+A+AEQ+GE L DA+ KL DLE ALQQAK+D+AR L +YQELMN KL LD
Sbjct: 400 AQRAKLEAAVAEAEQQGEATLSDAKCKLADLECALQQAKQDMARQLCEYQELMNAKLGLD 459
Query: 475 VEIATYRKLLEGEECRMSGDLSSNVTVSVTSSTISSNVASKAAFGGSGGRGSSSGGGYSS 534
+EIATYR+LLEGEE R+ + V +SV+SS + GS S GG S
Sbjct: 460 IEIATYRRLLEGEESRLCEGVGP-VNISVSSSRGGLVCGPEPLVAGS---TLSRGGVTFS 515
Query: 535 GSSSYGSGGRQSGSRGGSGGGGSIS 559
GSSS + S G S GG ++
Sbjct: 516 GSSSVCATSGVLASCGPSLGGARVA 540
Score = 39.7 bits (91), Expect = 0.009
Identities = 36/100 (36%), Positives = 41/100 (41%), Gaps = 17/100 (17%)
Query: 519 GGSGGRGSSSGGGYSSGSSSYGSGGRQSGSRGGSGGGGSISGGGYGSGGGSGGRYGSGGG 578
G G R + G YS ++ GS G R G+G G G G G G G G R S G
Sbjct: 48 GSFGSRSVITFGSYSPRIAAVGSRPIHCGVRFGAGCG---MGFGDGRGVGLGPRADSCVG 104
Query: 579 SKGGSISGGGYGSGGGKHSSGGGSRGGSSSGGGYGSGGGG 618
G+ SG GYG GG G GY GG G
Sbjct: 105 LGFGAGSGIGYGFGG--------------PGFGYRVGGVG 130
>gi|89357932 keratin 5b [Homo sapiens]
Length = 520
Score = 433 bits (1114), Expect = e-121
Identities = 246/501 (49%), Positives = 329/501 (65%), Gaps = 30/501 (5%)
Query: 81 GGFGAAGGFGGRGGGFGGGSSFGGG-SGFSGGGFGGGGFGGGRFGGFGGPGGVGGLGGPG 139
GGF + GGF R +SFGG G G +G GG G RFG + G GPG
Sbjct: 28 GGFSSRGGFSSRSL-----NSFGGCLEGSRGSTWGSGGRLGVRFGEWSG--------GPG 74
Query: 140 -GFGPGGYPGGIHEVSVNQSLLQPLNVKVDPEIQNVKAQEREQIKTLNNKFASFIDKVRF 198
P PGGI EV++NQ+LL PL +++DP+ Q V+ QE ++I+TLNN+FASFIDKVRF
Sbjct: 75 LSLCP---PGGIQEVTINQNLLTPLKIEIDPQFQVVRTQETQEIRTLNNQFASFIDKVRF 131
Query: 199 LEQQNQVLQTKWELLQQMNVGTRPINLEPIFQGYIDSLKRYLDGLTAERTSQNSELNNMQ 258
LEQQN+VL+TKW LLQQ + LEP+F+ +D L++ L+ L ER + ++EL +
Sbjct: 132 LEQQNKVLETKWHLLQQQGLSGSQQGLEPVFEACLDQLRKQLEQLQGERGALDAELKACR 191
Query: 259 DLVEDYKKKYEDEINKRTAAENDFVTLKKDVDNAYMIKVELQSKVDLLNQEIEFLKVLYD 318
D E+YK KYE+E ++R ENDFV LKKDVD ++ K+EL+ K++ L + + FLK L +
Sbjct: 192 DQEEEYKSKYEEEAHRRATLENDFVVLKKDVDGVFLSKMELEGKLEALREYLYFLKHLNE 251
Query: 319 AEISQIHQSVTDTNVILSMDNSRNLDLDSIIAEVKAQYEEIAQRSKEEAEALYHSKYEEL 378
E+ Q+ +DT+V+LSMDN+R LD SII EV+A+YEEIA+ SK EAEALY +KY+EL
Sbjct: 252 EELGQLQTQASDTSVVLSMDNNRYLDFSSIITEVRARYEEIARSSKAEAEALYQTKYQEL 311
Query: 379 QVTVGRHGDSLKEIKIEISELNRVIQRLQGEIAHVKKQCKNVQDAIADAEQRGEHALKDA 438
QV+ HGD ++E K++IS+L++ IQRLQ + ++KKQ ++Q AI DAEQRGE ALKDA
Sbjct: 312 QVSAQLHGDRMQETKVQISQLHQEIQRLQSQTENLKKQNASLQAAITDAEQRGELALKDA 371
Query: 439 RNKLNDLEEALQQAKEDLARLLRDYQELMNVKLALDVEIATYRKLLEGEECRMSGDLSSN 498
+ K+++LE AL+ AK++LARLL +YQEL + KL+LDVEIATYR+LLEGEECRMSG+ +S
Sbjct: 372 QAKVDELEAALRMAKQNLARLLCEYQELTSTKLSLDVEIATYRRLLEGEECRMSGECTSQ 431
Query: 499 VTVSVTSSTISSNVASKAAFGGSGGRGSSSGGGYSSGSSSYGSGGRQSGSRGGSGGGGSI 558
VT+ S+V A G G G S G SG S GS + +GG I
Sbjct: 432 VTI--------SSVGGSAVMSGGVGGGLGSTCGLGSGKGSPGS----CCTSIVTGGSNII 479
Query: 559 SGGGYGSGGGSGGRYGSGGGS 579
G G S GS GS
Sbjct: 480 LGSGKDPVLDSCSVSGSSAGS 500
Score = 36.6 bits (83), Expect = 0.073
Identities = 29/80 (36%), Positives = 36/80 (45%), Gaps = 11/80 (13%)
Query: 509 SSNVASKAAFGGSGGRGSSSGGGYSSGSSSYGSGGRQSGSRGGSGGGGSISGGGYGSGGG 568
S+ A A G G SS GG+SS S + GG GSRG + +GSGG
Sbjct: 13 SARSACSARSRGRSRGGFSSRGGFSSRSLN-SFGGCLEGSRGST----------WGSGGR 61
Query: 569 SGGRYGSGGGSKGGSISGGG 588
G R+G G G S+ G
Sbjct: 62 LGVRFGEWSGGPGLSLCPPG 81
>gi|67782365 keratin 7 [Homo sapiens]
Length = 469
Score = 430 bits (1106), Expect = e-120
Identities = 240/457 (52%), Positives = 306/457 (66%), Gaps = 26/457 (5%)
Query: 86 AGGFGGRGGGFGGGSSFGGGSGFSG-GGFGGGGFGGGRFGGFGGPGGVGGLGGPGGFGPG 144
+ F GRG S+ GG G S G G +GGP G G
Sbjct: 14 SAAFSGRGAQVRLSSARPGGLGSSSLYGLGASRPRVAVRSAYGGPVGAG----------- 62
Query: 145 GYPGGIHEVSVNQSLLQPLNVKVDPEIQNVKAQEREQIKTLNNKFASFIDKVRFLEQQNQ 204
I EV++NQSLL PL + DP +Q V+ +E EQIKTLNNKFASFIDKVRFLEQQN+
Sbjct: 63 -----IREVTINQSLLAPLRLDADPSLQRVRQEESEQIKTLNNKFASFIDKVRFLEQQNK 117
Query: 205 VLQTKWELLQQMNVGTRPINLEPIFQGYIDSLKRYLDGLTAERTSQNSELNNMQDLVEDY 264
+L+TKW LLQ+ + L IF+ I L+ L+ L + +EL +MQD+VED+
Sbjct: 118 LLETKWTLLQEQK-SAKSSRLPDIFEAQIAGLRGQLEALQVDGGRLEAELRSMQDVVEDF 176
Query: 265 KKKYEDEINKRTAAENDFVTLKKDVDNAYMIKVELQSKVDLLNQEIEFLKVLYDAEISQI 324
K KYEDEIN RTAAEN+FV LKKDVD AYM KVEL++KVD LN EI FL+ L + E++++
Sbjct: 177 KNKYEDEINHRTAAENEFVVLKKDVDAAYMSKVELEAKVDALNDEINFLRTLNETELTEL 236
Query: 325 HQSVTDTNVILSMDNSRNLDLDSIIAEVKAQYEEIAQRSKEEAEALYHSKYEELQVTVGR 384
++DT+V+LSMDNSR+LDLD IIAEVKAQYEE+A+ S+ EAEA Y +K+E LQ G+
Sbjct: 237 QSQISDTSVVLSMDNSRSLDLDGIIAEVKAQYEEMAKCSRAEAEAWYQTKFETLQAQAGK 296
Query: 385 HGDSLKEIKIEISELNRVIQRLQGEIAHVKKQCKNVQDAIADAEQRGEHALKDARNKLND 444
HGD L+ + EISE+NR IQRLQ EI ++K Q ++ AIA+AE+RGE ALKDAR K +
Sbjct: 297 HGDDLRNTRNEISEMNRAIQRLQAEIDNIKNQRAKLEAAIAEAEERGELALKDARAKQEE 356
Query: 445 LEEALQQAKEDLARLLRDYQELMNVKLALDVEIATYRKLLEGEECRMSGDLSSNVTVSVT 504
LE ALQ+ K+D+AR LR+YQELM+VKLALD+EIATYRKLLEGEE R++GD V +SV
Sbjct: 357 LEAALQRGKQDMARQLREYQELMSVKLALDIEIATYRKLLEGEESRLAGDGVGAVNISVM 416
Query: 505 SSTISSNVASKAAFGGSGGRGSSSGGGYSSGSSSYGS 541
+ST S+ GG G + GG S + S+ S
Sbjct: 417 NSTGGSS--------SGGGIGLTLGGTMGSNALSFSS 445
>gi|226246665 keratin 72 isoform 2 [Homo sapiens]
Length = 469
Score = 410 bits (1054), Expect = e-114
Identities = 255/541 (47%), Positives = 328/541 (60%), Gaps = 116/541 (21%)
Query: 21 GFSSGSAVVSGGSRRSTSSFSCLSRHGGGGGGFGGGGFGSRSLVGLGGTKSISISVAGGG 80
GFS SAV+SGG S++SF + G FGS+SL LGG++S+++S A
Sbjct: 15 GFSGCSAVLSGGIGSSSASFRARVK--------GSASFGSKSLSCLGGSRSLALSAAARR 66
Query: 81 GGFGAAGGFGGRGGGFGGGSSFGGGSGFSGGGFGGGGFGGGRFGGFGGPGGVGGLGGPGG 140
G GGR GGF VG G G
Sbjct: 67 G--------------------------------------GGRLGGF-----VGTAFGSAG 83
Query: 141 FGPGGY----PGGIHEVSVNQSLLQPLNVKVDPEIQNVKAQEREQIKTLNNKFASFIDKV 196
GP PGGI +V+VN+SLL PLNV++DPEIQ V+AQEREQIK LNNKFASFIDKV
Sbjct: 84 LGPKCPSVCPPGGIPQVTVNKSLLAPLNVEMDPEIQRVRAQEREQIKALNNKFASFIDKV 143
Query: 197 RFLEQQNQVLQTKWELLQQMNVGTRPINLEPIFQGYIDSLKRYLDGLTAERTSQNSELNN 256
RFLEQQNQVL+TKW LLQQ+++ NLEPI++GYI +L++ L+ L+ + +SEL N
Sbjct: 144 RFLEQQNQVLETKWNLLQQLDLNNCRKNLEPIYEGYISNLQKQLEMLSGDGVRLDSELRN 203
Query: 257 MQDLVEDYKKKYEDEINKRTAAENDFVTLKKDVDNAYMIKVELQSKVDLLNQEIEFLKVL 316
MQDLVEDYKK+YE EIN+RTAAEN+FV LKKDVD AYM KVELQ+KVD L EI+F K L
Sbjct: 204 MQDLVEDYKKRYEVEINRRTAAENEFVVLKKDVDAAYMNKVELQAKVDSLTDEIKFFKCL 263
Query: 317 YDAEISQIHQSVTDTNVILSMDNSRNLDLDSIIAEVKAQYEEIAQRSKEEAEALYHSKYE 376
Y+ EI+QI ++DT+++LSMDN+R+LDLDSIIAEV+AQYEEIA +SK EAE LY +K
Sbjct: 264 YEGEITQIQSHISDTSIVLSMDNNRDLDLDSIIAEVRAQYEEIALKSKAEAETLYQTKCA 323
Query: 377 ELQVTVG---RHGD-SLKEIKIEISELNRVIQRLQGEIAHVKKQCKNVQDAIADAEQRGE 432
+L+ + + GD +LK+ + ++ EL E
Sbjct: 324 DLETAIADAEQRGDCALKDARAKLDEL--------------------------------E 351
Query: 433 HALKDARNKLNDLEEALQQAKEDLARLLRDYQELMNVKLALDVEIATYRKLLEGEECRMS 492
AL A+ + LAR+LR+YQEL+++KLALD+EIATYRKLLE EECRMS
Sbjct: 352 GALHQAKEE--------------LARMLREYQELVSLKLALDMEIATYRKLLESEECRMS 397
Query: 493 GDLSSNVTVSVTSSTISSNVASKAAFGGSGGRGSSSGGGYSSGSSSYGSGGRQSGSRGGS 552
G+ ++V++SV SST + G+GG G S G G SS S SY + ++G
Sbjct: 398 GEYPNSVSISVISSTNA----------GAGGAGFSMGFGASS-SYSYKTAAADVKTKGSC 446
Query: 553 G 553
G
Sbjct: 447 G 447
Score = 32.7 bits (73), Expect = 1.1
Identities = 25/75 (33%), Positives = 29/75 (38%), Gaps = 3/75 (4%)
Query: 547 GSRGGSGGGGSISGGGYGSGGGSGGRYGSGG---GSKGGSISGGGYGSGGGKHSSGGGSR 603
G R G G ++ GG GS S G GSK S GG + GG R
Sbjct: 11 GERLGFSGCSAVLSGGIGSSSASFRARVKGSASFGSKSLSCLGGSRSLALSAAARRGGGR 70
Query: 604 GGSSSGGGYGSGGGG 618
G G +GS G G
Sbjct: 71 LGGFVGTAFGSAGLG 85
>gi|4504935 keratin 85 [Homo sapiens]
Length = 507
Score = 393 bits (1010), Expect = e-109
Identities = 253/558 (45%), Positives = 337/558 (60%), Gaps = 82/558 (14%)
Query: 5 ISCKSRGRGGGGGGFRGFSSGSAVVSGGSRRSTSSFSCLSR--HGGGGGGFGGGGFGSRS 62
+SC+S G G R FSS SAV T + C+S + G G GFGSRS
Sbjct: 1 MSCRSYRISSGCGVTRNFSSCSAVAP-----KTGNRCCISAAPYRGVSCYRGLTGFGSRS 55
Query: 63 LVGLGGTKSISISVAGGGGGFGAAGGFGGRGGGFGGGSSFGGGSGFSGGGFGGGGFGGGR 122
L LG G A GGF R G G SFG SG
Sbjct: 56 LCNLGSC-----------GPRIAVGGF--RAGSCG--RSFGYRSG--------------- 85
Query: 123 FGGFGGPGGVGGLGGPGGFGPGGYPGGIHEVSVNQSLLQPLNVKVDPEIQNVKAQEREQI 182
G+ GP P I VSVN+SLL PLN+++DP Q VK +E+EQI
Sbjct: 86 -----------GVCGPS-------PPCITTVSVNESLLTPLNLEIDPNAQCVKQEEKEQI 127
Query: 183 KTLNNKFASFIDKVRFLEQQNQVLQTKWELLQQMNVGTRPINLEPIFQGYIDSLKRYLDG 242
K+LN++FA+FIDKVRFLEQQN++L+TKW+ Q N NLEP+F GYI++L+R +
Sbjct: 128 KSLNSRFAAFIDKVRFLEQQNKLLETKWQFYQ--NQRCCESNLEPLFSGYIETLRREAEC 185
Query: 243 LTAERTSQNSELNNMQDLVEDYKKKYEDEINKRTAAENDFVTLKKDVDNAYMIKVELQSK 302
+ A+ SELN++Q+++E YKKKYE+E+ R AEN+FV LKKDVD AY+ K +L++
Sbjct: 186 VEADSGRLASELNHVQEVLEGYKKKYEEEVALRATAENEFVVLKKDVDCAYLRKSDLEAN 245
Query: 303 VDLLNQEIEFLKVLYDAEISQIHQSVTDTNVILSMDNSRNLDLDSIIAEVKAQYEEIAQR 362
V+ L +E FL+ LY+ EI + ++DT+VI+ MDNSR+L++D IIAE+KAQY+++A R
Sbjct: 246 VEALVEESSFLRRLYEEEIRVLQAHISDTSVIVKMDNSRDLNMDCIIAEIKAQYDDVASR 305
Query: 363 SKEEAEALYHSKYEELQVTVGRHGDSLKEIKIEISELNRVIQRLQGEIAHVKKQCKNVQD 422
S+ EAE+ Y SK EE++ TV RHG++L+ K EI+ELNR+IQRL EI + K Q ++
Sbjct: 306 SRAEAESWYRSKCEEMKATVIRHGETLRRTKEEINELNRMIQRLTAEIENAKCQRAKLEA 365
Query: 423 AIADAEQRGEHALKDARNKLNDLEEALQQAKEDLARLLRDYQELMNVKLALDVEIATYRK 482
A+A+AEQ+GE AL DAR KL +LE ALQ+AK+D+A LL++YQE+MN KL LD+EIATYR+
Sbjct: 366 AVAEAEQQGEAALSDARCKLAELEGALQKAKQDMACLLKEYQEVMNSKLGLDIEIATYRR 425
Query: 483 LLEGEECRM-SGDLSSNVTVSVTSSTISSNVASKAAFGGSGGRGSSSGGGYSSGSSSYGS 541
LLEGEE R+ G S NV V SSS GG S G SY +
Sbjct: 426 LLEGEEHRLCEGVGSVNVCV------------------------SSSRGGVSCGGLSYST 461
Query: 542 GGRQSGSRGGSGGGGSIS 559
+ + G S GGSI+
Sbjct: 462 TPGRQITSGPSAIGGSIT 479
>gi|27477127 keratin 82 [Homo sapiens]
Length = 513
Score = 389 bits (999), Expect = e-108
Identities = 222/453 (49%), Positives = 301/453 (66%), Gaps = 23/453 (5%)
Query: 125 GFGGPGGVGGLGG--PG-GFGPGGYPGG---IHEVSVNQSLLQPLNVKVDPEIQNVKAQE 178
GFG P GG PG G+ G G I V++N+SLL PL +++DP +Q VK E
Sbjct: 61 GFGRPRVASRCGGTLPGFGYRLGATCGPSACITPVTINESLLVPLALEIDPTVQRVKRDE 120
Query: 179 REQIKTLNNKFASFIDKVRFLEQQNQVLQTKWELLQQMNVGTRPINLEPIFQGYIDSLKR 238
+EQIK LNN+FASFI+KVRFLEQ+N++L+TKW +QQ N+EPIF+GYI +L+R
Sbjct: 121 KEQIKCLNNRFASFINKVRFLEQKNKLLETKWNFMQQQRCCQT--NIEPIFEGYISALRR 178
Query: 239 YLDGLTAERTSQNSELNNMQDLVEDYKKKYEDEINKRTAAENDFVTLKKDVDNAYMIKVE 298
LD ++ +R SEL ++Q +E YKKKYE+E++ R EN+FV LKKDVD A+++K +
Sbjct: 179 QLDCVSGDRVRLESELCSLQAALEGYKKKYEEELSLRPCVENEFVALKKDVDTAFLMKAD 238
Query: 299 LQSKVDLLNQEIEFLKVLYDAEISQIHQSVTDTNVILSMDNSRNLDLDSIIAEVKAQYEE 358
L++ + L QEI+FLK LY+ EI + +++T+VI+ MDNSR LD+D IIAE+KAQY++
Sbjct: 239 LETNAEALVQEIDFLKSLYEEEICLLQSQISETSVIVKMDNSRELDVDGIIAEIKAQYDD 298
Query: 359 IAQRSKEEAEALYHSKYEELQVTVGRHGDSLKEIKIEISELNRVIQRLQGEIAHVKKQCK 418
IA RSK EAEA Y +YEEL+VT G H D+L+ K EI E+N++IQRLQ E +VK Q
Sbjct: 299 IASRSKAEAEAWYQCRYEELRVTAGNHCDNLRNRKNEILEMNKLIQRLQQETENVKAQRC 358
Query: 419 NVQDAIADAEQRGEHALKDARNKLNDLEEALQQAKEDLARLLRDYQELMNVKLALDVEIA 478
++ AIA+AEQ+GE AL DA+ KL LEEALQ+AK+D+A LL++YQE+MN KL LD+EIA
Sbjct: 359 KLEGAIAEAEQQGEAALNDAKCKLAGLEEALQKAKQDMACLLKEYQEVMNSKLGLDIEIA 418
Query: 479 TYRKLLEGEECRMSGDLSSNVTVSVTSST---------ISSNVASKAAFGGSGGRGSSSG 529
TYR+LLEGEE R+ + V +SV+SS +S+ V S +GG
Sbjct: 419 TYRRLLEGEEHRLCEGIGP-VNISVSSSKGAFLYEPCGVSTPVLSTGVLRSNGGCSIVGT 477
Query: 530 GGY-----SSGSSSYGSGGRQSGSRGGSGGGGS 557
G G S GSG + S + G G S
Sbjct: 478 GELYVPCEPQGLLSCGSGRKSSMTLGAGGSSPS 510
>gi|169790853 keratin, hair, basic, 1 [Homo sapiens]
Length = 505
Score = 388 bits (997), Expect = e-108
Identities = 240/530 (45%), Positives = 327/530 (61%), Gaps = 59/530 (11%)
Query: 50 GGGFGGGGFGSRSLVG-LGGTKSISISVAGGGGGF-GAAGGFGGRG--GGFGGGSSFGGG 105
G GFGG F S G G I+ + G + G GGFG GGF GS G
Sbjct: 4 GSGFGGRAFSCISACGPRPGRCCITAAPYRGISCYRGLTGGFGSHSVCGGFRAGSC---G 60
Query: 106 SGFSGGGFGGGGFGGGRFGGFGGPGGVGGLGGPGGFGPGGYPGGIHEVSVNQSLLQPLNV 165
F G R GG GP P I VSVN+SLL PLN+
Sbjct: 61 RSF-----------GYRSGGVCGPS----------------PPCITTVSVNESLLTPLNL 93
Query: 166 KVDPEIQNVKAQEREQIKTLNNKFASFIDKVRFLEQQNQVLQTKWELLQQMNVGTRPINL 225
++DP Q VK +E+EQIK+LN++FA+FIDKVRFLEQQN++L+TK + Q N NL
Sbjct: 94 EIDPNAQCVKQEEKEQIKSLNSRFAAFIDKVRFLEQQNKLLETKLQFYQ--NRECCQSNL 151
Query: 226 EPIFQGYIDSLKRYLDGLTAERTSQNSELNNMQDLVEDYKKKYEDEINKRTAAENDFVTL 285
EP+F+GYI++L+R + + A+ SELN++Q+++E YKKKYE+E++ R AEN+FV L
Sbjct: 152 EPLFEGYIETLRREAECVEADSGRLASELNHVQEVLEGYKKKYEEEVSLRATAENEFVAL 211
Query: 286 KKDVDNAYMIKVELQSKVDLLNQEIEFLKVLYDAEISQIHQSVTDTNVILSMDNSRNLDL 345
KKDVD AY+ K +L++ V+ L QEI+FL+ LY+ EI + ++DT+V++ +DNSR+L++
Sbjct: 212 KKDVDCAYLRKSDLEANVEALIQEIDFLRRLYEEEILILQSHISDTSVVVKLDNSRDLNM 271
Query: 346 DSIIAEVKAQYEEIAQRSKEEAEALYHSKYEELQVTVGRHGDSLKEIKIEISELNRVIQR 405
D IIAE+KAQY++I RS+ EAE+ Y SK EE++ TV RHG++L+ K EI+ELNR+IQR
Sbjct: 272 DCIIAEIKAQYDDIVTRSRAEAESWYRSKCEEMKATVIRHGETLRRTKEEINELNRMIQR 331
Query: 406 LQGEIAHVKKQCKNVQDAIADAEQRGEHALKDARNKLNDLEEALQQAKEDLARLLRDYQE 465
L E+ + K Q ++ A+A +EQ+GE AL DAR KL +LE ALQ+AK+D+A L+R+YQE
Sbjct: 332 LTAEVENAKCQNSKLEAAVAQSEQQGEAALSDARCKLAELEGALQKAKQDMACLIREYQE 391
Query: 466 LMNVKLALDVEIATYRKLLEGEECRM-------------------SGDL----SSNVTVS 502
+MN KL LD+EIATYR+LLEGEE R+ GDL S VT S
Sbjct: 392 VMNSKLGLDIEIATYRRLLEGEEQRLCEGIGAVNVCVSSSRGGVVCGDLCVSGSRPVTGS 451
Query: 503 VTSSTISSNVASKAAFGGSGGRGSSSGGGYSSGSSSYGSGGRQSGSRGGS 552
V S+ + NVA G+ +++ GG S G S G GS G S
Sbjct: 452 VCSAPCNGNVAVSTGLCAPCGQLNTTCGGGSCGVGSCGISSLGVGSCGSS 501
>gi|239755818 PREDICTED: hypothetical protein isoform 2 [Homo
sapiens]
Length = 486
Score = 381 bits (979), Expect = e-106
Identities = 225/484 (46%), Positives = 314/484 (64%), Gaps = 35/484 (7%)
Query: 79 GGGGFGAAGGFGGRGGGFG-GGSSFGGGSGFSG--GGFGGGGFGGG-RFGGFGGPGGV-- 132
GG F G R G + + G S + G GGFG GG R G G G
Sbjct: 8 GGRAFSCISACGPRPGRCCITAAPYRGISCYRGLTGGFGSHSVCGGFRAGSCGRSFGYRS 67
Query: 133 GGLGGPGGFGPGGYPGGIHEVSVNQSLLQPLNVKVDPEIQNVKAQEREQIKTLNNKFASF 192
GG+ GP P I VSVN+SLL PLN+++DP Q VK +E+EQIK+LN++FA+F
Sbjct: 68 GGVCGPS-------PPCITTVSVNESLLTPLNLEIDPNAQCVKQEEKEQIKSLNSRFAAF 120
Query: 193 IDKVRFLEQQNQVLQTKWELLQQMNVGTRPINLEPIFQGYIDSLKRYLDGLTAERTSQNS 252
IDKVRFLEQQN++L+TK + Q N NLEP+F+GYI++L+R + + A+ S
Sbjct: 121 IDKVRFLEQQNKLLETKLQFYQ--NRECCQSNLEPLFEGYIETLRREAECVEADSGRLAS 178
Query: 253 ELNNMQDLVEDYKKKYEDEINKRTAAENDFVTLKKDVDNAYMIKVELQSKVDLLNQEIEF 312
ELN++Q+++E YKKKYE+E++ R AEN+FV LKKDVD AY+ K +L++ V+ L QEI+F
Sbjct: 179 ELNHVQEVLEGYKKKYEEEVSLRATAENEFVALKKDVDCAYLRKSDLEANVEALIQEIDF 238
Query: 313 LKVLYDAEISQIHQSVTDTNVILSMDNSRNLDLDSIIAEVKAQYEEIAQRSKEEAEALYH 372
L+ LY+ EI + ++DT+V++ +DNSR+L++D IIAE+KAQY++I RS+ EAE+ Y
Sbjct: 239 LRRLYEEEIRVLQSHISDTSVVVKLDNSRDLNMDCIIAEIKAQYDDIVTRSRAEAESWYR 298
Query: 373 SKYEELQVTVGRHGDSLKEIKIEISELNRVIQRLQGEIAHVKKQCKNVQDAIADAEQRGE 432
SK EE++ TV RHG++L+ K EI+ELNR+IQRL E+ + K Q ++ A+A +EQ+GE
Sbjct: 299 SKCEEMKATVIRHGETLRRTKEEINELNRMIQRLTAEVENAKCQNSKLEAAVAQSEQQGE 358
Query: 433 HALKDARNKLNDLEEALQQAKEDLARLLRDYQELMNVKLALDVEIATYRKLLEGEECRM- 491
AL DAR KL +LE ALQ+AK+D+A L+R+YQE+MN KL LD+EIATYR+LLEGEE R+
Sbjct: 359 AALSDARCKLAELEGALQKAKQDMACLIREYQEVMNSKLGLDIEIATYRRLLEGEEQRLC 418
Query: 492 ------------------SGDLSSNVTVSVTSSTISSNVA-SKAAFGGSGGRGSSSGGGY 532
GDL ++ T V S+ +SS + S G + S+ G
Sbjct: 419 EGVGSVNVCVSSSRGGVVCGDLCASTTAPVVSTRVSSVPSNSNVVVGTTNACAPSARVGV 478
Query: 533 SSGS 536
GS
Sbjct: 479 CGGS 482
>gi|239755816 PREDICTED: hypothetical protein isoform 1 [Homo
sapiens]
Length = 486
Score = 381 bits (979), Expect = e-106
Identities = 225/484 (46%), Positives = 314/484 (64%), Gaps = 35/484 (7%)
Query: 79 GGGGFGAAGGFGGRGGGFG-GGSSFGGGSGFSG--GGFGGGGFGGG-RFGGFGGPGGV-- 132
GG F G R G + + G S + G GGFG GG R G G G
Sbjct: 8 GGRAFSCISACGPRPGRCCITAAPYRGISCYRGLTGGFGSHSVCGGFRAGSCGRSFGYRS 67
Query: 133 GGLGGPGGFGPGGYPGGIHEVSVNQSLLQPLNVKVDPEIQNVKAQEREQIKTLNNKFASF 192
GG+ GP P I VSVN+SLL PLN+++DP Q VK +E+EQIK+LN++FA+F
Sbjct: 68 GGVCGPS-------PPCITTVSVNESLLTPLNLEIDPNAQCVKQEEKEQIKSLNSRFAAF 120
Query: 193 IDKVRFLEQQNQVLQTKWELLQQMNVGTRPINLEPIFQGYIDSLKRYLDGLTAERTSQNS 252
IDKVRFLEQQN++L+TK + Q N NLEP+F+GYI++L+R + + A+ S
Sbjct: 121 IDKVRFLEQQNKLLETKLQFYQ--NRECCQSNLEPLFEGYIETLRREAECVEADSGRLAS 178
Query: 253 ELNNMQDLVEDYKKKYEDEINKRTAAENDFVTLKKDVDNAYMIKVELQSKVDLLNQEIEF 312
ELN++Q+++E YKKKYE+E++ R AEN+FV LKKDVD AY+ K +L++ V+ L QEI+F
Sbjct: 179 ELNHVQEVLEGYKKKYEEEVSLRATAENEFVALKKDVDCAYLRKSDLEANVEALIQEIDF 238
Query: 313 LKVLYDAEISQIHQSVTDTNVILSMDNSRNLDLDSIIAEVKAQYEEIAQRSKEEAEALYH 372
L+ LY+ EI + ++DT+V++ +DNSR+L++D IIAE+KAQY++I RS+ EAE+ Y
Sbjct: 239 LRRLYEEEIRVLQSHISDTSVVVKLDNSRDLNMDCIIAEIKAQYDDIVTRSRAEAESWYR 298
Query: 373 SKYEELQVTVGRHGDSLKEIKIEISELNRVIQRLQGEIAHVKKQCKNVQDAIADAEQRGE 432
SK EE++ TV RHG++L+ K EI+ELNR+IQRL E+ + K Q ++ A+A +EQ+GE
Sbjct: 299 SKCEEMKATVIRHGETLRRTKEEINELNRMIQRLTAEVENAKCQNSKLEAAVAQSEQQGE 358
Query: 433 HALKDARNKLNDLEEALQQAKEDLARLLRDYQELMNVKLALDVEIATYRKLLEGEECRM- 491
AL DAR KL +LE ALQ+AK+D+A L+R+YQE+MN KL LD+EIATYR+LLEGEE R+
Sbjct: 359 AALSDARCKLAELEGALQKAKQDMACLIREYQEVMNSKLGLDIEIATYRRLLEGEEQRLC 418
Query: 492 ------------------SGDLSSNVTVSVTSSTISSNVA-SKAAFGGSGGRGSSSGGGY 532
GDL ++ T V S+ +SS + S G + S+ G
Sbjct: 419 EGVGSVNVCVSSSRGGVVCGDLCASTTAPVVSTRVSSVPSNSNVVVGTTNACAPSARVGV 478
Query: 533 SSGS 536
GS
Sbjct: 479 CGGS 482
>gi|239755814 PREDICTED: hypothetical protein isoform 3 [Homo
sapiens]
Length = 486
Score = 381 bits (979), Expect = e-106
Identities = 225/484 (46%), Positives = 314/484 (64%), Gaps = 35/484 (7%)
Query: 79 GGGGFGAAGGFGGRGGGFG-GGSSFGGGSGFSG--GGFGGGGFGGG-RFGGFGGPGGV-- 132
GG F G R G + + G S + G GGFG GG R G G G
Sbjct: 8 GGRAFSCISACGPRPGRCCITAAPYRGISCYRGLTGGFGSHSVCGGFRAGSCGRSFGYRS 67
Query: 133 GGLGGPGGFGPGGYPGGIHEVSVNQSLLQPLNVKVDPEIQNVKAQEREQIKTLNNKFASF 192
GG+ GP P I VSVN+SLL PLN+++DP Q VK +E+EQIK+LN++FA+F
Sbjct: 68 GGVCGPS-------PPCITTVSVNESLLTPLNLEIDPNAQCVKQEEKEQIKSLNSRFAAF 120
Query: 193 IDKVRFLEQQNQVLQTKWELLQQMNVGTRPINLEPIFQGYIDSLKRYLDGLTAERTSQNS 252
IDKVRFLEQQN++L+TK + Q N NLEP+F+GYI++L+R + + A+ S
Sbjct: 121 IDKVRFLEQQNKLLETKLQFYQ--NRECCQSNLEPLFEGYIETLRREAECVEADSGRLAS 178
Query: 253 ELNNMQDLVEDYKKKYEDEINKRTAAENDFVTLKKDVDNAYMIKVELQSKVDLLNQEIEF 312
ELN++Q+++E YKKKYE+E++ R AEN+FV LKKDVD AY+ K +L++ V+ L QEI+F
Sbjct: 179 ELNHVQEVLEGYKKKYEEEVSLRATAENEFVALKKDVDCAYLRKSDLEANVEALIQEIDF 238
Query: 313 LKVLYDAEISQIHQSVTDTNVILSMDNSRNLDLDSIIAEVKAQYEEIAQRSKEEAEALYH 372
L+ LY+ EI + ++DT+V++ +DNSR+L++D IIAE+KAQY++I RS+ EAE+ Y
Sbjct: 239 LRRLYEEEIRVLQSHISDTSVVVKLDNSRDLNMDCIIAEIKAQYDDIVTRSRAEAESWYR 298
Query: 373 SKYEELQVTVGRHGDSLKEIKIEISELNRVIQRLQGEIAHVKKQCKNVQDAIADAEQRGE 432
SK EE++ TV RHG++L+ K EI+ELNR+IQRL E+ + K Q ++ A+A +EQ+GE
Sbjct: 299 SKCEEMKATVIRHGETLRRTKEEINELNRMIQRLTAEVENAKCQNSKLEAAVAQSEQQGE 358
Query: 433 HALKDARNKLNDLEEALQQAKEDLARLLRDYQELMNVKLALDVEIATYRKLLEGEECRM- 491
AL DAR KL +LE ALQ+AK+D+A L+R+YQE+MN KL LD+EIATYR+LLEGEE R+
Sbjct: 359 AALSDARCKLAELEGALQKAKQDMACLIREYQEVMNSKLGLDIEIATYRRLLEGEEQRLC 418
Query: 492 ------------------SGDLSSNVTVSVTSSTISSNVA-SKAAFGGSGGRGSSSGGGY 532
GDL ++ T V S+ +SS + S G + S+ G
Sbjct: 419 EGVGSVNVCVSSSRGGVVCGDLCASTTAPVVSTRVSSVPSNSNVVVGTTNACAPSARVGV 478
Query: 533 SSGS 536
GS
Sbjct: 479 CGGS 482
>gi|14318422 keratin 86 [Homo sapiens]
Length = 486
Score = 381 bits (979), Expect = e-106
Identities = 225/484 (46%), Positives = 314/484 (64%), Gaps = 35/484 (7%)
Query: 79 GGGGFGAAGGFGGRGGGFG-GGSSFGGGSGFSG--GGFGGGGFGGG-RFGGFGGPGGV-- 132
GG F G R G + + G S + G GGFG GG R G G G
Sbjct: 8 GGRAFSCISACGPRPGRCCITAAPYRGISCYRGLTGGFGSHSVCGGFRAGSCGRSFGYRS 67
Query: 133 GGLGGPGGFGPGGYPGGIHEVSVNQSLLQPLNVKVDPEIQNVKAQEREQIKTLNNKFASF 192
GG+ GP P I VSVN+SLL PLN+++DP Q VK +E+EQIK+LN++FA+F
Sbjct: 68 GGVCGPS-------PPCITTVSVNESLLTPLNLEIDPNAQCVKQEEKEQIKSLNSRFAAF 120
Query: 193 IDKVRFLEQQNQVLQTKWELLQQMNVGTRPINLEPIFQGYIDSLKRYLDGLTAERTSQNS 252
IDKVRFLEQQN++L+TK + Q N NLEP+F+GYI++L+R + + A+ S
Sbjct: 121 IDKVRFLEQQNKLLETKLQFYQ--NRECCQSNLEPLFEGYIETLRREAECVEADSGRLAS 178
Query: 253 ELNNMQDLVEDYKKKYEDEINKRTAAENDFVTLKKDVDNAYMIKVELQSKVDLLNQEIEF 312
ELN++Q+++E YKKKYE+E++ R AEN+FV LKKDVD AY+ K +L++ V+ L QEI+F
Sbjct: 179 ELNHVQEVLEGYKKKYEEEVSLRATAENEFVALKKDVDCAYLRKSDLEANVEALIQEIDF 238
Query: 313 LKVLYDAEISQIHQSVTDTNVILSMDNSRNLDLDSIIAEVKAQYEEIAQRSKEEAEALYH 372
L+ LY+ EI + ++DT+V++ +DNSR+L++D IIAE+KAQY++I RS+ EAE+ Y
Sbjct: 239 LRRLYEEEIRVLQSHISDTSVVVKLDNSRDLNMDCIIAEIKAQYDDIVTRSRAEAESWYR 298
Query: 373 SKYEELQVTVGRHGDSLKEIKIEISELNRVIQRLQGEIAHVKKQCKNVQDAIADAEQRGE 432
SK EE++ TV RHG++L+ K EI+ELNR+IQRL E+ + K Q ++ A+A +EQ+GE
Sbjct: 299 SKCEEMKATVIRHGETLRRTKEEINELNRMIQRLTAEVENAKCQNSKLEAAVAQSEQQGE 358
Query: 433 HALKDARNKLNDLEEALQQAKEDLARLLRDYQELMNVKLALDVEIATYRKLLEGEECRM- 491
AL DAR KL +LE ALQ+AK+D+A L+R+YQE+MN KL LD+EIATYR+LLEGEE R+
Sbjct: 359 AALSDARCKLAELEGALQKAKQDMACLIREYQEVMNSKLGLDIEIATYRRLLEGEEQRLC 418
Query: 492 ------------------SGDLSSNVTVSVTSSTISSNVA-SKAAFGGSGGRGSSSGGGY 532
GDL ++ T V S+ +SS + S G + S+ G
Sbjct: 419 EGVGSVNVCVSSSRGGVVCGDLCASTTAPVVSTRVSSVPSNSNVVVGTTNACAPSARVGV 478
Query: 533 SSGS 536
GS
Sbjct: 479 CGGS 482
>gi|169790841 keratin 83 [Homo sapiens]
Length = 493
Score = 377 bits (967), Expect = e-104
Identities = 219/455 (48%), Positives = 305/455 (67%), Gaps = 15/455 (3%)
Query: 111 GGFGGGGFGGG-RFGGFGGPGGV--GGLGGPGGFGPGGYPGGIHEVSVNQSLLQPLNVKV 167
GGFG GG R G G G GG+ GP P I VSVN+SLL PLN+++
Sbjct: 48 GGFGSHSVCGGFRAGSCGRSFGYRSGGVCGPS-------PPCITTVSVNESLLTPLNLEI 100
Query: 168 DPEIQNVKAQEREQIKTLNNKFASFIDKVRFLEQQNQVLQTKWELLQQMNVGTRPINLEP 227
DP Q VK +E+EQIK+LN++FA+FIDKVRFLEQQN++L+TK + Q N NLEP
Sbjct: 101 DPNAQCVKQEEKEQIKSLNSRFAAFIDKVRFLEQQNKLLETKLQFYQ--NRECCQSNLEP 158
Query: 228 IFQGYIDSLKRYLDGLTAERTSQNSELNNMQDLVEDYKKKYEDEINKRTAAENDFVTLKK 287
+F GYI++L+R + + A+ SELN++Q+++E YKKKYE+E+ R AEN+FV LKK
Sbjct: 159 LFAGYIETLRREAECVEADSGRLASELNHVQEVLEGYKKKYEEEVALRATAENEFVALKK 218
Query: 288 DVDNAYMIKVELQSKVDLLNQEIEFLKVLYDAEISQIHQSVTDTNVILSMDNSRNLDLDS 347
DVD AY+ K +L++ V+ L QEI+FL+ LY+ EI + ++DT+V++ +DNSR+L++D
Sbjct: 219 DVDCAYLRKSDLEANVEALIQEIDFLRRLYEEEIRILQSHISDTSVVVKLDNSRDLNMDC 278
Query: 348 IIAEVKAQYEEIAQRSKEEAEALYHSKYEELQVTVGRHGDSLKEIKIEISELNRVIQRLQ 407
I+AE+KAQY++IA RS+ EAE+ Y SK EE++ TV RHG++L+ K EI+ELNR+IQRL
Sbjct: 279 IVAEIKAQYDDIATRSRAEAESWYRSKCEEMKATVIRHGETLRRTKEEINELNRMIQRLT 338
Query: 408 GEIAHVKKQCKNVQDAIADAEQRGEHALKDARNKLNDLEEALQQAKEDLARLLRDYQELM 467
E+ + K Q ++ A+A +EQ+GE AL DAR KL +LE ALQ+AK+D+A L+R+YQE+M
Sbjct: 339 AEVENAKCQNSKLEAAVAQSEQQGEAALSDARCKLAELEGALQKAKQDMACLIREYQEVM 398
Query: 468 NVKLALDVEIATYRKLLEGEECRMSGDLSSNVTVSVTSSTISSNVASKAAFGGSGGRGSS 527
N KL LD+EIATYR+LLEGEE R+ + + V V V+SS V GS S
Sbjct: 399 NSKLGLDIEIATYRRLLEGEEQRLCEGVEA-VNVCVSSSR-GGVVCGDLCVSGSRPVTGS 456
Query: 528 SGGGYSSGSSSYGSG-GRQSGSRGGSGGGGSISGG 561
+G+ +G + G + GGGS G
Sbjct: 457 VCSAPCNGNLVVSTGLCKPCGQLNTTCGGGSCGQG 491
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.310 0.135 0.382
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 26,740,294
Number of Sequences: 37866
Number of extensions: 1776872
Number of successful extensions: 95031
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 903
Number of HSP's successfully gapped in prelim test: 855
Number of HSP's that attempted gapping in prelim test: 15971
Number of HSP's gapped (non-prelim): 30509
length of query: 639
length of database: 18,247,518
effective HSP length: 109
effective length of query: 530
effective length of database: 14,120,124
effective search space: 7483665720
effective search space used: 7483665720
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.7 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Home |
Table of Contents |
Search text |
Search genes |
Search sequences |
Purchase |
FAQ |
Blog |
Help
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.