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Search of human proteins with 46409558
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|46409558 beta-defensin 32 precursor [Homo sapiens]
(95 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|46409558 beta-defensin 32 precursor [Homo sapiens] 204 9e-54
gi|16905373 beta-defensin 118 [Homo sapiens] 49 7e-07
gi|58865339 defensin, beta 121 [Homo sapiens] 44 4e-05
gi|76563936 defensin, beta 125 preproprotein [Homo sapiens] 43 5e-05
gi|23503331 defensin, beta 123 precursor [Homo sapiens] 40 4e-04
gi|82734223 beta-defensin 124 [Homo sapiens] 38 0.002
gi|169166494 PREDICTED: hypothetical protein [Homo sapiens] 37 0.003
gi|239753808 PREDICTED: hypothetical protein [Homo sapiens] 35 0.010
gi|239748372 PREDICTED: hypothetical protein [Homo sapiens] 35 0.010
gi|50344744 beta-defensin 108B [Homo sapiens] 35 0.010
gi|83582802 beta-defensin 128 [Homo sapiens] 35 0.017
gi|23503329 defensin, beta 119 isoform c precursor [Homo sapiens] 32 0.14
gi|116517226 beta-defensin 135 [Homo sapiens] 31 0.24
gi|37704382 defensin, beta 119 isoform a precursor [Homo sapiens] 31 0.24
gi|239756124 PREDICTED: hypothetical protein [Homo sapiens] 30 0.42
gi|22748611 defensin, beta 106A precursor [Homo sapiens] 30 0.42
gi|21040279 defensin, beta 127 preproprotein [Homo sapiens] 30 0.42
gi|103485143 defensin, beta 106B precursor [Homo sapiens] 30 0.42
gi|239744548 PREDICTED: hypothetical protein XP_002343194 [Homo ... 29 0.93
gi|83582800 beta-defensin 116 [Homo sapiens] 28 1.6
gi|239753810 PREDICTED: similar to beta-defensin 130 [Homo sapiens] 27 2.7
gi|239748374 PREDICTED: hypothetical protein XP_002346650 [Homo ... 27 2.7
gi|239742299 PREDICTED: hypothetical protein XP_002342487 [Homo ... 27 2.7
gi|169172908 PREDICTED: similar to beta-defensin 130 [Homo sapiens] 27 3.5
gi|83699414 beta-defensin 130 [Homo sapiens] 27 3.5
gi|4507725 transthyretin precursor [Homo sapiens] 27 4.6
gi|74136827 beta-defensin 134 [Homo sapiens] 26 6.0
gi|66346695 fibrillin 2 precursor [Homo sapiens] 26 7.8
gi|23200025 tumor necrosis factor receptor superfamily, member 2... 26 7.8
gi|23200023 tumor necrosis factor receptor superfamily, member 2... 26 7.8
>gi|46409558 beta-defensin 32 precursor [Homo sapiens]
Length = 95
Score = 204 bits (520), Expect = 9e-54
Identities = 95/95 (100%), Positives = 95/95 (100%)
Query: 1 MKFLLLVLAALGFLTQVIPASAGGSKCVSNTPGYCRTCCHWGETALFMCNASRKCCISYS 60
MKFLLLVLAALGFLTQVIPASAGGSKCVSNTPGYCRTCCHWGETALFMCNASRKCCISYS
Sbjct: 1 MKFLLLVLAALGFLTQVIPASAGGSKCVSNTPGYCRTCCHWGETALFMCNASRKCCISYS 60
Query: 61 FLPKPDLPQLIGNHWQSRRRNTQRKDKKQQTTVTS 95
FLPKPDLPQLIGNHWQSRRRNTQRKDKKQQTTVTS
Sbjct: 61 FLPKPDLPQLIGNHWQSRRRNTQRKDKKQQTTVTS 95
>gi|16905373 beta-defensin 118 [Homo sapiens]
Length = 123
Score = 49.3 bits (116), Expect = 7e-07
Identities = 28/57 (49%), Positives = 30/57 (52%), Gaps = 1/57 (1%)
Query: 1 MKFLLLVLAALGFLTQVIPASAGGSKCVSNTPGYCRTCCHWGETALFMCNASRKCCI 57
MK LLL L L L QVIPA +G KC N G+CR C GE C R CCI
Sbjct: 1 MKLLLLALPMLVLLPQVIPAYSGEKKCW-NRSGHCRKQCKDGEAVKDTCKNLRACCI 56
>gi|58865339 defensin, beta 121 [Homo sapiens]
Length = 76
Score = 43.5 bits (101), Expect = 4e-05
Identities = 26/68 (38%), Positives = 32/68 (47%), Gaps = 6/68 (8%)
Query: 1 MKFLLLVLAALGFLTQVIPASAGGSKCVSNTPGYCRTCCHWGETALFMCNASRKCCISYS 60
MK LLL+L L QV P KC + G CRT C E +C KCC+
Sbjct: 1 MKLLLLLLTVTLLLAQVTPVM----KCWGKS-GRCRTTCKESEVYYILCKTEAKCCVDPK 55
Query: 61 FLP-KPDL 67
++P KP L
Sbjct: 56 YVPVKPKL 63
>gi|76563936 defensin, beta 125 preproprotein [Homo sapiens]
Length = 156
Score = 43.1 bits (100), Expect = 5e-05
Identities = 23/71 (32%), Positives = 31/71 (43%), Gaps = 3/71 (4%)
Query: 1 MKFLLLVLAALGFLTQVIPASAGGSKCVSNTPGYCRTCCHWGETALFMCNASRKCC---I 57
M L+L G LT+V S KC N G+CR C E + +C CC I
Sbjct: 1 MNILMLTFIICGLLTRVTKGSFEPQKCWKNNVGHCRRRCLDTERYILLCRNKLSCCISII 60
Query: 58 SYSFLPKPDLP 68
S+ + +P P
Sbjct: 61 SHEYTRRPAFP 71
>gi|23503331 defensin, beta 123 precursor [Homo sapiens]
Length = 67
Score = 40.0 bits (92), Expect = 4e-04
Identities = 23/64 (35%), Positives = 31/64 (48%), Gaps = 3/64 (4%)
Query: 1 MKFLLLVLAALGFLTQVIPASAGGSKCVSNTPGYCRTCCHWGETALFMCNASRKCCISYS 60
MK LLL L L L+Q+ P GG++ N G CR C E C ++ CC+
Sbjct: 1 MKLLLLTLTVLLLLSQLTP---GGTQRCWNLYGKCRYRCSKKERVYVYCINNKMCCVKPK 57
Query: 61 FLPK 64
+ PK
Sbjct: 58 YQPK 61
>gi|82734223 beta-defensin 124 [Homo sapiens]
Length = 71
Score = 38.1 bits (87), Expect = 0.002
Identities = 23/65 (35%), Positives = 31/65 (47%), Gaps = 1/65 (1%)
Query: 1 MKFLLLVLAALGFLTQVIPASAGGSKCVSNTPGYCRTCCHWGETALFMCNASRKCCISYS 60
M LLL L AL L V + +C G C+T C ET + +C + CC+SY+
Sbjct: 1 MTQLLLFLVALLVLGHVPSGRSEFKRCWKGQ-GACQTYCTRQETYMHLCPDASLCCLSYA 59
Query: 61 FLPKP 65
P P
Sbjct: 60 LKPPP 64
>gi|169166494 PREDICTED: hypothetical protein [Homo sapiens]
Length = 73
Score = 37.0 bits (84), Expect = 0.003
Identities = 19/64 (29%), Positives = 29/64 (45%)
Query: 1 MKFLLLVLAALGFLTQVIPASAGGSKCVSNTPGYCRTCCHWGETALFMCNASRKCCISYS 60
M+ +L+ A F++QV+PA + G CR C E + C SR CC+
Sbjct: 1 MRIAVLLFAIFFFMSQVLPARGKFKEICERPNGSCRDFCLETEIHVGRCLNSRPCCLPLG 60
Query: 61 FLPK 64
P+
Sbjct: 61 HQPR 64
>gi|239753808 PREDICTED: hypothetical protein [Homo sapiens]
Length = 83
Score = 35.4 bits (80), Expect = 0.010
Identities = 18/64 (28%), Positives = 29/64 (45%)
Query: 1 MKFLLLVLAALGFLTQVIPASAGGSKCVSNTPGYCRTCCHWGETALFMCNASRKCCISYS 60
++ +L+ A F++QV+PA + G CR C E + C SR CC+
Sbjct: 11 VRIAVLLFAIFFFMSQVLPARGKFKEICERPNGSCRDFCLETEIHVGRCLNSRPCCLPLG 70
Query: 61 FLPK 64
P+
Sbjct: 71 HQPR 74
>gi|239748372 PREDICTED: hypothetical protein [Homo sapiens]
Length = 83
Score = 35.4 bits (80), Expect = 0.010
Identities = 18/64 (28%), Positives = 29/64 (45%)
Query: 1 MKFLLLVLAALGFLTQVIPASAGGSKCVSNTPGYCRTCCHWGETALFMCNASRKCCISYS 60
++ +L+ A F++QV+PA + G CR C E + C SR CC+
Sbjct: 11 VRIAVLLFAIFFFMSQVLPARGKFKEICERPNGSCRDFCLETEIHVGRCLNSRPCCLPLG 70
Query: 61 FLPK 64
P+
Sbjct: 71 HQPR 74
>gi|50344744 beta-defensin 108B [Homo sapiens]
Length = 73
Score = 35.4 bits (80), Expect = 0.010
Identities = 18/64 (28%), Positives = 29/64 (45%)
Query: 1 MKFLLLVLAALGFLTQVIPASAGGSKCVSNTPGYCRTCCHWGETALFMCNASRKCCISYS 60
M+ +L+ A F++QV+PA + G CR C E + C S+ CC+
Sbjct: 1 MRIAVLLFAIFFFMSQVLPARGKFKEICERPNGSCRDFCLETEIHVGRCLNSQPCCLPLG 60
Query: 61 FLPK 64
P+
Sbjct: 61 HQPR 64
>gi|83582802 beta-defensin 128 [Homo sapiens]
Length = 93
Score = 34.7 bits (78), Expect = 0.017
Identities = 20/53 (37%), Positives = 25/53 (47%), Gaps = 2/53 (3%)
Query: 4 LLLVLAALGFLTQVIPASAGGSKCVSNTPGYCRTCCHWGETALFMCNASRKCC 56
L LVL L F +V+ A KC + GYCR C GE C + + CC
Sbjct: 3 LFLVLIILLF--EVLTDGARLKKCFNKVTGYCRKKCKVGERYEIGCLSGKLCC 53
>gi|23503329 defensin, beta 119 isoform c precursor [Homo sapiens]
Length = 88
Score = 31.6 bits (70), Expect = 0.14
Identities = 10/30 (33%), Positives = 17/30 (56%)
Query: 33 GYCRTCCHWGETALFMCNASRKCCISYSFL 62
G+CR C GE ++ C ++CC+ +L
Sbjct: 27 GHCRLLCKDGEDSIIRCRNRKRCCVPSRYL 56
>gi|116517226 beta-defensin 135 [Homo sapiens]
Length = 77
Score = 30.8 bits (68), Expect = 0.24
Identities = 18/67 (26%), Positives = 27/67 (40%), Gaps = 7/67 (10%)
Query: 4 LLLVLAALGFLTQVIPASAGGSKCVSNT-------PGYCRTCCHWGETALFMCNASRKCC 56
+LL L L L V P +G + + G CR C E +C+ CC
Sbjct: 6 VLLALVVLNLLFYVPPGRSGPNVYIQKIFASCWRLQGTCRPKCLKNEQYRILCDTIHLCC 65
Query: 57 ISYSFLP 63
++ +LP
Sbjct: 66 VNPKYLP 72
>gi|37704382 defensin, beta 119 isoform a precursor [Homo sapiens]
Length = 84
Score = 30.8 bits (68), Expect = 0.24
Identities = 19/58 (32%), Positives = 26/58 (44%), Gaps = 2/58 (3%)
Query: 1 MKFLLLVLAALGFLTQ-VIPASAGGSKCVSNTPGYCRTCCHWGETALFMCNASRKCCI 57
MK L L LA L + + VI +C+ N+ G CR C E C + CC+
Sbjct: 1 MKLLYLFLAILLAIEEPVISGKRHILRCMGNS-GICRASCKKNEQPYLYCRNCQSCCL 57
>gi|239756124 PREDICTED: hypothetical protein [Homo sapiens]
Length = 348
Score = 30.0 bits (66), Expect = 0.42
Identities = 21/61 (34%), Positives = 26/61 (42%), Gaps = 7/61 (11%)
Query: 15 TQVIPASAG---GSKCVSNTPGYCRTCCHWGETALFMCNASRKCCISYSFLPKPDLPQLI 71
T + P + G G C N G +CC W F C A R C++ S P P LP
Sbjct: 177 TAIFPGTRGSGRGGGC--NCGGGSCSCCRWSMAGPFPC-ARRATCLA-SLSPPPKLPTAP 232
Query: 72 G 72
G
Sbjct: 233 G 233
>gi|22748611 defensin, beta 106A precursor [Homo sapiens]
Length = 65
Score = 30.0 bits (66), Expect = 0.42
Identities = 19/56 (33%), Positives = 25/56 (44%), Gaps = 2/56 (3%)
Query: 1 MKFLLLVLAALGFLTQVIPASAGGSKCVSNTPGYCRTCCHWGETALFMCNASRKCC 56
M+ L + A L FLT A KC + G C+ C E + +C S KCC
Sbjct: 1 MRTFLFLFAVLFFLTPAKNAFFD-EKC-NKLKGTCKNNCGKNEELIALCQKSLKCC 54
>gi|21040279 defensin, beta 127 preproprotein [Homo sapiens]
Length = 99
Score = 30.0 bits (66), Expect = 0.42
Identities = 16/56 (28%), Positives = 25/56 (44%), Gaps = 3/56 (5%)
Query: 4 LLLVLAALGFLTQVIPASAGGSKCVSN-TPGYCRTCCHWGETALFMCNASRKCCIS 58
L +++A L F + KC +N G+CR C E +C R CC++
Sbjct: 3 LFMIIAILLFQKPTVTEQL--KKCWNNYVQGHCRKICRVNEVPEALCENGRYCCLN 56
>gi|103485143 defensin, beta 106B precursor [Homo sapiens]
Length = 65
Score = 30.0 bits (66), Expect = 0.42
Identities = 19/56 (33%), Positives = 25/56 (44%), Gaps = 2/56 (3%)
Query: 1 MKFLLLVLAALGFLTQVIPASAGGSKCVSNTPGYCRTCCHWGETALFMCNASRKCC 56
M+ L + A L FLT A KC + G C+ C E + +C S KCC
Sbjct: 1 MRTFLFLFAVLFFLTPAKNAFFD-EKC-NKLKGTCKNNCGKNEELIALCQKSLKCC 54
>gi|239744548 PREDICTED: hypothetical protein XP_002343194 [Homo
sapiens]
Length = 192
Score = 28.9 bits (63), Expect = 0.93
Identities = 20/86 (23%), Positives = 37/86 (43%), Gaps = 2/86 (2%)
Query: 4 LLLVLAALGFLTQVIPASAGGSK--CVSNTPGYCRTCCHWGETALFMCNASRKCCISYSF 61
LLL+L L + + G ++ C+S + R C E + C KCC ++
Sbjct: 69 LLLILLLFSILLSPVRGALGPAEVHCLSLSGVCRRDVCKVVEDQIGACRRRMKCCRAWWI 128
Query: 62 LPKPDLPQLIGNHWQSRRRNTQRKDK 87
L P ++ ++ + +R +K K
Sbjct: 129 LMPIPTPLIMSDYQEPLKRCRSKKAK 154
>gi|83582800 beta-defensin 116 [Homo sapiens]
Length = 102
Score = 28.1 bits (61), Expect = 1.6
Identities = 21/69 (30%), Positives = 25/69 (36%), Gaps = 9/69 (13%)
Query: 1 MKFLLLVLAALGFLTQVIPA----SAGGSKCVSNTP-----GYCRTCCHWGETALFMCNA 51
MK L+ +A L L Q P S G P G CR C E C
Sbjct: 4 MKPCLMTIAILMILAQKTPGGLFRSHNGKSREPWNPCELYQGMCRNACREYEIQYLTCPN 63
Query: 52 SRKCCISYS 60
+KCC+ S
Sbjct: 64 DQKCCLKLS 72
>gi|239753810 PREDICTED: similar to beta-defensin 130 [Homo sapiens]
Length = 128
Score = 27.3 bits (59), Expect = 2.7
Identities = 17/54 (31%), Positives = 26/54 (48%), Gaps = 5/54 (9%)
Query: 4 LLLVLAALGFLTQVIPASAGGSKCVSNTPGYCRT-CCHWGETALFMCNASRKCC 56
L + L +T VIP G +C++ G CR C + + +CN +KCC
Sbjct: 60 LFVTLIPKAKMTGVIP---GQKQCIA-LKGVCRDKLCSTLDDTIGICNEGKKCC 109
>gi|239748374 PREDICTED: hypothetical protein XP_002346650 [Homo
sapiens]
Length = 128
Score = 27.3 bits (59), Expect = 2.7
Identities = 17/54 (31%), Positives = 26/54 (48%), Gaps = 5/54 (9%)
Query: 4 LLLVLAALGFLTQVIPASAGGSKCVSNTPGYCRT-CCHWGETALFMCNASRKCC 56
L + L +T VIP G +C++ G CR C + + +CN +KCC
Sbjct: 60 LFVTLIPKAKMTGVIP---GQKQCIA-LKGVCRDKLCSTLDDTIGICNEGKKCC 109
>gi|239742299 PREDICTED: hypothetical protein XP_002342487 [Homo
sapiens]
Length = 128
Score = 27.3 bits (59), Expect = 2.7
Identities = 17/54 (31%), Positives = 26/54 (48%), Gaps = 5/54 (9%)
Query: 4 LLLVLAALGFLTQVIPASAGGSKCVSNTPGYCRT-CCHWGETALFMCNASRKCC 56
L + L +T VIP G +C++ G CR C + + +CN +KCC
Sbjct: 60 LFVTLIPKAKMTGVIP---GQKQCIA-LKGVCRDKLCSTLDDTIGICNEGKKCC 109
>gi|169172908 PREDICTED: similar to beta-defensin 130 [Homo
sapiens]
Length = 79
Score = 26.9 bits (58), Expect = 3.5
Identities = 18/60 (30%), Positives = 25/60 (41%), Gaps = 4/60 (6%)
Query: 1 MKFLLLVLAALGFLTQVIPASAG---GSKCVSNTPGYCRT-CCHWGETALFMCNASRKCC 56
MK L+ L F+T + G G K G CR C + + +CN +KCC
Sbjct: 1 MKLHSLISVLLLFVTLIPKGKTGVIPGQKQCIALKGVCRDKLCSTLDDTIGICNEGKKCC 60
>gi|83699414 beta-defensin 130 [Homo sapiens]
Length = 79
Score = 26.9 bits (58), Expect = 3.5
Identities = 18/60 (30%), Positives = 25/60 (41%), Gaps = 4/60 (6%)
Query: 1 MKFLLLVLAALGFLTQVIPASAG---GSKCVSNTPGYCRT-CCHWGETALFMCNASRKCC 56
MK L+ L F+T + G G K G CR C + + +CN +KCC
Sbjct: 1 MKLHSLISVLLLFVTLIPKGKTGVIPGQKQCIALKGVCRDKLCSTLDDTIGICNEGKKCC 60
>gi|4507725 transthyretin precursor [Homo sapiens]
Length = 147
Score = 26.6 bits (57), Expect = 4.6
Identities = 12/26 (46%), Positives = 16/26 (61%)
Query: 2 KFLLLVLAALGFLTQVIPASAGGSKC 27
+ LLL LA L F+++ P G SKC
Sbjct: 5 RLLLLCLAGLVFVSEAGPTGTGESKC 30
>gi|74136827 beta-defensin 134 [Homo sapiens]
Length = 66
Score = 26.2 bits (56), Expect = 6.0
Identities = 19/62 (30%), Positives = 26/62 (41%), Gaps = 7/62 (11%)
Query: 1 MKFLLLVLAALGFLTQVIP-----ASAGGSKCVSNTPGYCRTCCHWGETALFMCNASRKC 55
MK LL+V L V+ +S KC N G CR C+ E + C +C
Sbjct: 1 MKPLLVVFVFLFLWDPVLAGINSLSSEMHKKCYKN--GICRLECYESEMLVAYCMFQLEC 58
Query: 56 CI 57
C+
Sbjct: 59 CV 60
>gi|66346695 fibrillin 2 precursor [Homo sapiens]
Length = 2912
Score = 25.8 bits (55), Expect = 7.8
Identities = 11/42 (26%), Positives = 20/42 (47%), Gaps = 5/42 (11%)
Query: 20 ASAGGSKCVSNTPGYC-----RTCCHWGETALFMCNASRKCC 56
+S+ G++C+ N G C +T C ++ + S CC
Sbjct: 2371 SSSSGTECLDNRQGLCFAEVLQTICQMASSSRNLVTKSECCC 2412
>gi|23200025 tumor necrosis factor receptor superfamily, member 25
isoform 4 precursor [Homo sapiens]
Length = 372
Score = 25.8 bits (55), Expect = 7.8
Identities = 9/18 (50%), Positives = 13/18 (72%)
Query: 25 SKCVSNTPGYCRTCCHWG 42
S+CVS++P YC+ C G
Sbjct: 83 SQCVSSSPFYCQPCLDCG 100
>gi|23200023 tumor necrosis factor receptor superfamily, member 25
isoform 3 precursor [Homo sapiens]
Length = 380
Score = 25.8 bits (55), Expect = 7.8
Identities = 9/18 (50%), Positives = 13/18 (72%)
Query: 25 SKCVSNTPGYCRTCCHWG 42
S+CVS++P YC+ C G
Sbjct: 128 SQCVSSSPFYCQPCLDCG 145
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.324 0.134 0.446
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 3,950,120
Number of Sequences: 37866
Number of extensions: 167692
Number of successful extensions: 527
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 22
Number of HSP's successfully gapped in prelim test: 12
Number of HSP's that attempted gapping in prelim test: 504
Number of HSP's gapped (non-prelim): 34
length of query: 95
length of database: 18,247,518
effective HSP length: 66
effective length of query: 29
effective length of database: 15,748,362
effective search space: 456702498
effective search space used: 456702498
T: 11
A: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.6 bits)
S2: 55 (25.8 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Search text |
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.