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Search of human proteins with 46367787
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|46367787 poly(A) binding protein, cytoplasmic 1 [Homo
sapiens]
(636 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|46367787 poly(A) binding protein, cytoplasmic 1 [Homo sapiens] 1267 0.0
gi|45238849 poly(A) binding protein, cytoplasmic 3 [Homo sapiens] 1151 0.0
gi|208431836 poly A binding protein, cytoplasmic 4 isoform 3 [Ho... 965 0.0
gi|4504715 poly A binding protein, cytoplasmic 4 isoform 2 [Homo... 960 0.0
gi|208431833 poly A binding protein, cytoplasmic 4 isoform 1 [Ho... 955 0.0
gi|185135971 poly(A)-binding protein, cytoplasmic 1-like [Homo s... 847 0.0
gi|168229150 poly(A) binding protein, cytoplasmic 4-like [Homo s... 546 e-155
gi|18201888 poly(A) binding protein, cytoplasmic 5 [Homo sapiens] 480 e-135
gi|109948285 poly(A) binding protein, cytoplasmic 1-like 2B [Hom... 327 3e-89
gi|61175237 poly(A) binding protein, cytoplasmic 1-like 2A [Homo... 327 3e-89
gi|239753150 PREDICTED: similar to poly(A) binding protein, cyto... 147 2e-35
gi|5032069 splicing factor 3b, subunit 4 [Homo sapiens] 121 2e-27
gi|38201714 ELAV-like 1 [Homo sapiens] 119 8e-27
gi|188219591 TIA1 protein isoform 2 [Homo sapiens] 119 1e-26
gi|188219593 TIA1 protein isoform 1 [Homo sapiens] 116 6e-26
gi|4507499 TIA-1 related protein isoform 1 [Homo sapiens] 115 2e-25
gi|115511032 ELAV (embryonic lethal, abnormal vision, Drosophila... 111 2e-24
gi|49355761 ELAV-like protein 3 isoform 1 [Homo sapiens] 110 5e-24
gi|77695912 TIA-1 related protein isoform 2 [Homo sapiens] 108 2e-23
gi|221316773 ELAV-like 4 isoform 5 [Homo sapiens] 107 4e-23
gi|221316771 ELAV-like 4 isoform 4 [Homo sapiens] 107 4e-23
gi|221316769 ELAV-like 4 isoform 3 [Homo sapiens] 107 4e-23
gi|221316767 ELAV-like 4 isoform 2 [Homo sapiens] 107 4e-23
gi|49355765 ELAV-like protein 3 isoform 2 [Homo sapiens] 106 6e-23
gi|55956788 nucleolin [Homo sapiens] 104 3e-22
gi|221316765 ELAV-like 4 isoform 1 [Homo sapiens] 102 1e-21
gi|209862867 poly-U binding splicing factor 60KDa isoform c [Hom... 98 2e-20
gi|17978512 poly-U binding splicing factor 60KDa isoform a [Homo... 98 2e-20
gi|17298690 poly-U binding splicing factor 60KDa isoform b [Homo... 94 3e-19
gi|8400718 RNA binding motif, single stranded interacting protei... 91 4e-18
>gi|46367787 poly(A) binding protein, cytoplasmic 1 [Homo sapiens]
Length = 636
Score = 1267 bits (3278), Expect = 0.0
Identities = 636/636 (100%), Positives = 636/636 (100%)
Query: 1 MNPSAPSYPMASLYVGDLHPDVTEAMLYEKFSPAGPILSIRVCRDMITRRSLGYAYVNFQ 60
MNPSAPSYPMASLYVGDLHPDVTEAMLYEKFSPAGPILSIRVCRDMITRRSLGYAYVNFQ
Sbjct: 1 MNPSAPSYPMASLYVGDLHPDVTEAMLYEKFSPAGPILSIRVCRDMITRRSLGYAYVNFQ 60
Query: 61 QPADAERALDTMNFDVIKGKPVRIMWSQRDPSLRKSGVGNIFIKNLDKSIDNKALYDTFS 120
QPADAERALDTMNFDVIKGKPVRIMWSQRDPSLRKSGVGNIFIKNLDKSIDNKALYDTFS
Sbjct: 61 QPADAERALDTMNFDVIKGKPVRIMWSQRDPSLRKSGVGNIFIKNLDKSIDNKALYDTFS 120
Query: 121 AFGNILSCKVVCDENGSKGYGFVHFETQEAAERAIEKMNGMLLNDRKVFVGRFKSRKERE 180
AFGNILSCKVVCDENGSKGYGFVHFETQEAAERAIEKMNGMLLNDRKVFVGRFKSRKERE
Sbjct: 121 AFGNILSCKVVCDENGSKGYGFVHFETQEAAERAIEKMNGMLLNDRKVFVGRFKSRKERE 180
Query: 181 AELGARAKEFTNVYIKNFGEDMDDERLKDLFGKFGPALSVKVMTDESGKSKGFGFVSFER 240
AELGARAKEFTNVYIKNFGEDMDDERLKDLFGKFGPALSVKVMTDESGKSKGFGFVSFER
Sbjct: 181 AELGARAKEFTNVYIKNFGEDMDDERLKDLFGKFGPALSVKVMTDESGKSKGFGFVSFER 240
Query: 241 HEDAQKAVDEMNGKELNGKQIYVGRAQKKVERQTELKRKFEQMKQDRITRYQGVNLYVKN 300
HEDAQKAVDEMNGKELNGKQIYVGRAQKKVERQTELKRKFEQMKQDRITRYQGVNLYVKN
Sbjct: 241 HEDAQKAVDEMNGKELNGKQIYVGRAQKKVERQTELKRKFEQMKQDRITRYQGVNLYVKN 300
Query: 301 LDDGIDDERLRKEFSPFGTITSAKVMMEGGRSKGFGFVCFSSPEEATKAVTEMNGRIVAT 360
LDDGIDDERLRKEFSPFGTITSAKVMMEGGRSKGFGFVCFSSPEEATKAVTEMNGRIVAT
Sbjct: 301 LDDGIDDERLRKEFSPFGTITSAKVMMEGGRSKGFGFVCFSSPEEATKAVTEMNGRIVAT 360
Query: 361 KPLYVALAQRKEERQAHLTNQYMQRMASVRAVPNPVINPYQPAPPSGYFMAAIPQTQNRA 420
KPLYVALAQRKEERQAHLTNQYMQRMASVRAVPNPVINPYQPAPPSGYFMAAIPQTQNRA
Sbjct: 361 KPLYVALAQRKEERQAHLTNQYMQRMASVRAVPNPVINPYQPAPPSGYFMAAIPQTQNRA 420
Query: 421 AYYPPSQIAQLRPSPRWTAQGARPHPFQNMPGAIRPAAPRPPFSTMRPASSQVPRVMSTQ 480
AYYPPSQIAQLRPSPRWTAQGARPHPFQNMPGAIRPAAPRPPFSTMRPASSQVPRVMSTQ
Sbjct: 421 AYYPPSQIAQLRPSPRWTAQGARPHPFQNMPGAIRPAAPRPPFSTMRPASSQVPRVMSTQ 480
Query: 481 RVANTSTQTMGPRPAAAAAAATPAVRTVPQYKYAAGVRNPQQHLNAQPQVTMQQPAVHVQ 540
RVANTSTQTMGPRPAAAAAAATPAVRTVPQYKYAAGVRNPQQHLNAQPQVTMQQPAVHVQ
Sbjct: 481 RVANTSTQTMGPRPAAAAAAATPAVRTVPQYKYAAGVRNPQQHLNAQPQVTMQQPAVHVQ 540
Query: 541 GQEPLTASMLASAPPQEQKQMLGERLFPLIQAMHPTLAGKITGMLLEIDNSELLHMLESP 600
GQEPLTASMLASAPPQEQKQMLGERLFPLIQAMHPTLAGKITGMLLEIDNSELLHMLESP
Sbjct: 541 GQEPLTASMLASAPPQEQKQMLGERLFPLIQAMHPTLAGKITGMLLEIDNSELLHMLESP 600
Query: 601 ESLRSKVDEAVAVLQAHQAKEAAQKAVNSATGVPTV 636
ESLRSKVDEAVAVLQAHQAKEAAQKAVNSATGVPTV
Sbjct: 601 ESLRSKVDEAVAVLQAHQAKEAAQKAVNSATGVPTV 636
>gi|45238849 poly(A) binding protein, cytoplasmic 3 [Homo sapiens]
Length = 631
Score = 1151 bits (2978), Expect = 0.0
Identities = 586/637 (91%), Positives = 600/637 (94%), Gaps = 7/637 (1%)
Query: 1 MNPSAPSYPMASLYVGDLHPDVTEAMLYEKFSPAGPILSIRVCRDMITRRSLGYAYVNFQ 60
MNPS PSYP ASLYVGDLHPDVTEAMLYEKFSPAGPILSIR+CRD+IT S YAYVNFQ
Sbjct: 1 MNPSTPSYPTASLYVGDLHPDVTEAMLYEKFSPAGPILSIRICRDLITSGSSNYAYVNFQ 60
Query: 61 QPADAERALDTMNFDVIKGKPVRIMWSQRDPSLRKSGVGNIFIKNLDKSIDNKALYDTFS 120
DAE ALDTMNFDVIKGKPVRIMWSQRDPSLRKSGVGNIF+KNLDKSI+NKALYDT S
Sbjct: 61 HTKDAEHALDTMNFDVIKGKPVRIMWSQRDPSLRKSGVGNIFVKNLDKSINNKALYDTVS 120
Query: 121 AFGNILSCKVVCDENGSKGYGFVHFETQEAAERAIEKMNGMLLNDRKVFVGRFKSRKERE 180
AFGNILSC VVCDENGSKGYGFVHFET EAAERAI+KMNGMLLN RKVFVG+FKSRKERE
Sbjct: 121 AFGNILSCNVVCDENGSKGYGFVHFETHEAAERAIKKMNGMLLNGRKVFVGQFKSRKERE 180
Query: 181 AELGARAKEFTNVYIKNFGEDMDDERLKDLFGKFGPALSVKVMTDESGKSKGFGFVSFER 240
AELGARAKEF NVYIKNFGEDMDDERLKDLFGKFGPALSVKVMTDESGKSKGFGFVSFER
Sbjct: 181 AELGARAKEFPNVYIKNFGEDMDDERLKDLFGKFGPALSVKVMTDESGKSKGFGFVSFER 240
Query: 241 HEDAQKAVDEMNGKELNGKQIYVGRAQKKVERQTELKRKFEQMKQDRITRYQGVNLYVKN 300
HEDAQKAVDEMNGKELNGKQIYVGRAQKKVERQTELKR FEQMKQDRITRYQ VNLYVKN
Sbjct: 241 HEDAQKAVDEMNGKELNGKQIYVGRAQKKVERQTELKRTFEQMKQDRITRYQVVNLYVKN 300
Query: 301 LDDGIDDERLRKEFSPFGTITSAKVMMEGGRSKGFGFVCFSSPEEATKAVTEMNGRIVAT 360
LDDGIDDERLRK FSPFGTITSAKVMMEGGRSKGFGFVCFSSPEEATKAVTEMNGRIVAT
Sbjct: 301 LDDGIDDERLRKAFSPFGTITSAKVMMEGGRSKGFGFVCFSSPEEATKAVTEMNGRIVAT 360
Query: 361 KPLYVALAQRKEERQAHLTNQYMQRMASVRAVPNPVINPYQPAPPSGYFMAAIPQTQNRA 420
KPLYVALAQRKEERQA+LTN+YMQRMASVRAVPN Q APPSGYFM A+PQTQN A
Sbjct: 361 KPLYVALAQRKEERQAYLTNEYMQRMASVRAVPN------QRAPPSGYFMTAVPQTQNHA 414
Query: 421 AYYPPSQIAQLRPSPRWTAQGARPHPFQNMPGAIRPAAPRPPFSTMRPASSQVPRVMSTQ 480
AYYPPSQIA+LRPSPRWTAQGARPHPFQN P AIRP APR PFSTMRPASSQVPRVMSTQ
Sbjct: 415 AYYPPSQIARLRPSPRWTAQGARPHPFQNKPSAIRPGAPRVPFSTMRPASSQVPRVMSTQ 474
Query: 481 RVANTSTQTMGPRP-AAAAAAATPAVRTVPQYKYAAGVRNPQQHLNAQPQVTMQQPAVHV 539
RVANTSTQT+GPRP AAAAAAATPAVRTVP+YKYAAGVRNPQQH NAQPQVTMQQ AVHV
Sbjct: 475 RVANTSTQTVGPRPAAAAAAAATPAVRTVPRYKYAAGVRNPQQHRNAQPQVTMQQLAVHV 534
Query: 540 QGQEPLTASMLASAPPQEQKQMLGERLFPLIQAMHPTLAGKITGMLLEIDNSELLHMLES 599
QGQE LTAS LASAPPQ+QKQMLGERLFPLIQAMHPTLAGKITGMLLEIDNSELL+MLES
Sbjct: 535 QGQETLTASRLASAPPQKQKQMLGERLFPLIQAMHPTLAGKITGMLLEIDNSELLYMLES 594
Query: 600 PESLRSKVDEAVAVLQAHQAKEAAQKAVNSATGVPTV 636
PESLRSKVDEAVAVLQAHQAKEA QKAVNSATGVPTV
Sbjct: 595 PESLRSKVDEAVAVLQAHQAKEATQKAVNSATGVPTV 631
>gi|208431836 poly A binding protein, cytoplasmic 4 isoform 3 [Homo
sapiens]
Length = 631
Score = 965 bits (2495), Expect = 0.0
Identities = 504/641 (78%), Positives = 554/641 (86%), Gaps = 21/641 (3%)
Query: 1 MNPSAPSYPMASLYVGDLHPDVTEAMLYEKFSPAGPILSIRVCRDMITRRSLGYAYVNFQ 60
MN +A SYPMASLYVGDLH DVTEAMLYEKFSPAGP+LSIRVCRDMITRRSLGYAYVNFQ
Sbjct: 1 MNAAASSYPMASLYVGDLHSDVTEAMLYEKFSPAGPVLSIRVCRDMITRRSLGYAYVNFQ 60
Query: 61 QPADAERALDTMNFDVIKGKPVRIMWSQRDPSLRKSGVGNIFIKNLDKSIDNKALYDTFS 120
QPADAERALDTMNFDVIKGKP+RIMWSQRDPSLRKSGVGN+FIKNLDKSIDNKALYDTFS
Sbjct: 61 QPADAERALDTMNFDVIKGKPIRIMWSQRDPSLRKSGVGNVFIKNLDKSIDNKALYDTFS 120
Query: 121 AFGNILSCKVVCDENGSKGYGFVHFETQEAAERAIEKMNGMLLNDRKVFVGRFKSRKERE 180
AFGNILSCKVVCDENGSKGY FVHFETQEAA++AIEKMNGMLLNDRKVFVGRFKSRKERE
Sbjct: 121 AFGNILSCKVVCDENGSKGYAFVHFETQEAADKAIEKMNGMLLNDRKVFVGRFKSRKERE 180
Query: 181 AELGARAKEFTNVYIKNFGEDMDDERLKDLFGKFGPALSVKVMTDESGKSKGFGFVSFER 240
AELGA+AKEFTNVYIKNFGE++DDE LK+LF +FG LSVKVM D +GKSKGFGFVS+E+
Sbjct: 181 AELGAKAKEFTNVYIKNFGEEVDDESLKELFSQFGKTLSVKVMRDPNGKSKGFGFVSYEK 240
Query: 241 HEDAQKAVDEMNGKELNGKQIYVGRAQKKVERQTELKRKFEQMKQDRITRYQGVNLYVKN 300
HEDA KAV+EMNGKE++GK I+VGRAQKKVERQ ELKRKFEQ+KQ+RI+RYQGVNLY+KN
Sbjct: 241 HEDANKAVEEMNGKEISGKIIFVGRAQKKVERQAELKRKFEQLKQERISRYQGVNLYIKN 300
Query: 301 LDDGIDDERLRKEFSPFGTITSAKVMMEGGRSKGFGFVCFSSPEEATKAVTEMNGRIVAT 360
LDD IDDE+LRKEFSPFG+ITSAKVM+E GRSKGFGFVCFSSPEEATKAVTEMNGRIV +
Sbjct: 301 LDDTIDDEKLRKEFSPFGSITSAKVMLEDGRSKGFGFVCFSSPEEATKAVTEMNGRIVGS 360
Query: 361 KPLYVALAQRKEERQAHLTNQYMQRMASVRAVP-NPVINPYQPAPPSGYFMAAIPQTQNR 419
KPLYVALAQRKEER+AHLTNQYMQR+A +RA+P N ++N +QPA GYF+ A+PQ Q R
Sbjct: 361 KPLYVALAQRKEERKAHLTNQYMQRVAGMRALPANAILNQFQPA-AGGYFVPAVPQAQGR 419
Query: 420 AAYYPPSQIAQLRPSPRWTAQGARPHPFQNMPGAIRPAAPRPPFSTM-----RPASSQVP 474
YY P+Q+AQ+RP+PRW QG RP FQ MP AIR + PRP + PAS +P
Sbjct: 420 PPYYTPNQLAQMRPNPRW-QQGGRPQGFQGMPSAIRQSGPRPTLRHLAPTGNAPASRGLP 478
Query: 475 RVMSTQRV-ANTSTQTMGPRPAAAAAAATPAVRTVPQYKYAAGVRNPQQHLNAQPQVTMQ 533
+TQRV T+ Q + PR A AAAA R V YKYA+ VR+P H QP +
Sbjct: 479 --TTTQRVGVPTAVQNLAPRAAVAAAAP----RAVAPYKYASSVRSP--HPAIQP-LQAP 529
Query: 534 QPAVHVQGQEPLTASMLASAPPQEQKQMLGERLFPLIQAMHPTLAGKITGMLLEIDNSEL 593
QPAVHVQGQEPLTASMLA+APPQEQKQMLGERLFPLIQ MH LAGKITGMLLEIDNSEL
Sbjct: 530 QPAVHVQGQEPLTASMLAAAPPQEQKQMLGERLFPLIQTMHSNLAGKITGMLLEIDNSEL 589
Query: 594 LHMLESPESLRSKVDEAVAVLQAHQA-KEAAQK--AVNSAT 631
LHMLESPESLRSKVDEAVAVLQAH A KEAAQK AV +AT
Sbjct: 590 LHMLESPESLRSKVDEAVAVLQAHHAKKEAAQKVGAVAAAT 630
>gi|4504715 poly A binding protein, cytoplasmic 4 isoform 2 [Homo
sapiens]
Length = 644
Score = 960 bits (2481), Expect = 0.0
Identities = 500/652 (76%), Positives = 553/652 (84%), Gaps = 30/652 (4%)
Query: 1 MNPSAPSYPMASLYVGDLHPDVTEAMLYEKFSPAGPILSIRVCRDMITRRSLGYAYVNFQ 60
MN +A SYPMASLYVGDLH DVTEAMLYEKFSPAGP+LSIRVCRDMITRRSLGYAYVNFQ
Sbjct: 1 MNAAASSYPMASLYVGDLHSDVTEAMLYEKFSPAGPVLSIRVCRDMITRRSLGYAYVNFQ 60
Query: 61 QPADAERALDTMNFDVIKGKPVRIMWSQRDPSLRKSGVGNIFIKNLDKSIDNKALYDTFS 120
QPADAERALDTMNFDVIKGKP+RIMWSQRDPSLRKSGVGN+FIKNLDKSIDNKALYDTFS
Sbjct: 61 QPADAERALDTMNFDVIKGKPIRIMWSQRDPSLRKSGVGNVFIKNLDKSIDNKALYDTFS 120
Query: 121 AFGNILSCKVVCDENGSKGYGFVHFETQEAAERAIEKMNGMLLNDRKVFVGRFKSRKERE 180
AFGNILSCKVVCDENGSKGY FVHFETQEAA++AIEKMNGMLLNDRKVFVGRFKSRKERE
Sbjct: 121 AFGNILSCKVVCDENGSKGYAFVHFETQEAADKAIEKMNGMLLNDRKVFVGRFKSRKERE 180
Query: 181 AELGARAKEFTNVYIKNFGEDMDDERLKDLFGKFGPALSVKVMTDESGKSKGFGFVSFER 240
AELGA+AKEFTNVYIKNFGE++DDE LK+LF +FG LSVKVM D +GKSKGFGFVS+E+
Sbjct: 181 AELGAKAKEFTNVYIKNFGEEVDDESLKELFSQFGKTLSVKVMRDPNGKSKGFGFVSYEK 240
Query: 241 HEDAQKAVDEMNGKELNGKQIYVGRAQKKVERQTELKRKFEQMKQDRITRYQGVNLYVKN 300
HEDA KAV+EMNGKE++GK I+VGRAQKKVERQ ELKRKFEQ+KQ+RI+RYQGVNLY+KN
Sbjct: 241 HEDANKAVEEMNGKEISGKIIFVGRAQKKVERQAELKRKFEQLKQERISRYQGVNLYIKN 300
Query: 301 LDDGIDDERLRKEFSPFGTITSAKVMMEGGRSKGFGFVCFSSPEEATKAVTEMNGRIVAT 360
LDD IDDE+LRKEFSPFG+ITSAKVM+E GRSKGFGFVCFSSPEEATKAVTEMNGRIV +
Sbjct: 301 LDDTIDDEKLRKEFSPFGSITSAKVMLEDGRSKGFGFVCFSSPEEATKAVTEMNGRIVGS 360
Query: 361 KPLYVALAQRKEERQAHLTNQYMQRMASVRAVP-NPVINPYQPAPPSGYFMAAIPQTQNR 419
KPLYVALAQRKEER+AHLTNQYMQR+A +RA+P N ++N +QPA GYF+ A+PQ Q R
Sbjct: 361 KPLYVALAQRKEERKAHLTNQYMQRVAGMRALPANAILNQFQPA-AGGYFVPAVPQAQGR 419
Query: 420 AAYYPPSQIAQLRPSPRWTAQGARPHPFQNMPGAIRPAAPRPPFSTMRPASSQVPRVM-- 477
YY P+Q+AQ+RP+PRW QG RP FQ MP AIR + PRP + P S+ P +
Sbjct: 420 PPYYTPNQLAQMRPNPRW-QQGGRPQGFQGMPSAIRQSGPRPTLRHLAPTGSECPDRLAM 478
Query: 478 -------STQRVAN--------TSTQTMGPRPAAAAAAATPAVRTVPQYKYAAGVRNPQQ 522
+ Q + + T+ Q + PR A AAAA R V YKYA+ VR+P
Sbjct: 479 DFGGAGAAQQGLTDSCQSGGVPTAVQNLAPRAAVAAAAP----RAVAPYKYASSVRSP-- 532
Query: 523 HLNAQPQVTMQQPAVHVQGQEPLTASMLASAPPQEQKQMLGERLFPLIQAMHPTLAGKIT 582
H QP + QPAVHVQGQEPLTASMLA+APPQEQKQMLGERLFPLIQ MH LAGKIT
Sbjct: 533 HPAIQP-LQAPQPAVHVQGQEPLTASMLAAAPPQEQKQMLGERLFPLIQTMHSNLAGKIT 591
Query: 583 GMLLEIDNSELLHMLESPESLRSKVDEAVAVLQAHQA-KEAAQK--AVNSAT 631
GMLLEIDNSELLHMLESPESLRSKVDEAVAVLQAH A KEAAQK AV +AT
Sbjct: 592 GMLLEIDNSELLHMLESPESLRSKVDEAVAVLQAHHAKKEAAQKVGAVAAAT 643
>gi|208431833 poly A binding protein, cytoplasmic 4 isoform 1 [Homo
sapiens]
Length = 660
Score = 955 bits (2469), Expect = 0.0
Identities = 504/670 (75%), Positives = 555/670 (82%), Gaps = 50/670 (7%)
Query: 1 MNPSAPSYPMASLYVGDLHPDVTEAMLYEKFSPAGPILSIRVCRDMITRRSLGYAYVNFQ 60
MN +A SYPMASLYVGDLH DVTEAMLYEKFSPAGP+LSIRVCRDMITRRSLGYAYVNFQ
Sbjct: 1 MNAAASSYPMASLYVGDLHSDVTEAMLYEKFSPAGPVLSIRVCRDMITRRSLGYAYVNFQ 60
Query: 61 QPADAERALDTMNFDVIKGKPVRIMWSQRDPSLRKSGVGNIFIKNLDKSIDNKALYDTFS 120
QPADAERALDTMNFDVIKGKP+RIMWSQRDPSLRKSGVGN+FIKNLDKSIDNKALYDTFS
Sbjct: 61 QPADAERALDTMNFDVIKGKPIRIMWSQRDPSLRKSGVGNVFIKNLDKSIDNKALYDTFS 120
Query: 121 AFGNILSCKVVCDENGSKGYGFVHFETQEAAERAIEKMNGMLLNDRKVFVGRFKSRKERE 180
AFGNILSCKVVCDENGSKGY FVHFETQEAA++AIEKMNGMLLNDRKVFVGRFKSRKERE
Sbjct: 121 AFGNILSCKVVCDENGSKGYAFVHFETQEAADKAIEKMNGMLLNDRKVFVGRFKSRKERE 180
Query: 181 AELGARAKEFTNVYIKNFGEDMDDERLKDLFGKFGPALSVKVMTDESGKSKGFGFVSFER 240
AELGA+AKEFTNVYIKNFGE++DDE LK+LF +FG LSVKVM D +GKSKGFGFVS+E+
Sbjct: 181 AELGAKAKEFTNVYIKNFGEEVDDESLKELFSQFGKTLSVKVMRDPNGKSKGFGFVSYEK 240
Query: 241 HEDAQKAVDEMNGKELNGKQIYVGRAQKKVERQTELKRKFEQMKQDRITRYQGVNLYVKN 300
HEDA KAV+EMNGKE++GK I+VGRAQKKVERQ ELKRKFEQ+KQ+RI+RYQGVNLY+KN
Sbjct: 241 HEDANKAVEEMNGKEISGKIIFVGRAQKKVERQAELKRKFEQLKQERISRYQGVNLYIKN 300
Query: 301 LDDGIDDERLRKEFSPFGTITSAKVMMEGGRSKGFGFVCFSSPEEATKAVTEMNGRIVAT 360
LDD IDDE+LRKEFSPFG+ITSAKVM+E GRSKGFGFVCFSSPEEATKAVTEMNGRIV +
Sbjct: 301 LDDTIDDEKLRKEFSPFGSITSAKVMLEDGRSKGFGFVCFSSPEEATKAVTEMNGRIVGS 360
Query: 361 KPLYVALAQRKEERQAHLTNQYMQRMASVRAVP-NPVINPYQPAPPSGYFMAAIPQTQNR 419
KPLYVALAQRKEER+AHLTNQYMQR+A +RA+P N ++N +QPA GYF+ A+PQ Q R
Sbjct: 361 KPLYVALAQRKEERKAHLTNQYMQRVAGMRALPANAILNQFQPA-AGGYFVPAVPQAQGR 419
Query: 420 AAYYPPSQIAQLRPSPRWTAQGARPHPFQNMPGAIRPAAPRPPFSTM-----RPASSQVP 474
YY P+Q+AQ+RP+PRW QG RP FQ MP AIR + PRP + PAS +P
Sbjct: 420 PPYYTPNQLAQMRPNPRW-QQGGRPQGFQGMPSAIRQSGPRPTLRHLAPTGNAPASRGLP 478
Query: 475 RVMSTQRVAN------------------------------TSTQTMGPRPAAAAAAATPA 504
+TQRV + T+ Q + PR A AAAA
Sbjct: 479 --TTTQRVGSECPDRLAMDFGGAGAAQQGLTDSCQSGGVPTAVQNLAPRAAVAAAAP--- 533
Query: 505 VRTVPQYKYAAGVRNPQQHLNAQPQVTMQQPAVHVQGQEPLTASMLASAPPQEQKQMLGE 564
R V YKYA+ VR+P H QP + QPAVHVQGQEPLTASMLA+APPQEQKQMLGE
Sbjct: 534 -RAVAPYKYASSVRSP--HPAIQP-LQAPQPAVHVQGQEPLTASMLAAAPPQEQKQMLGE 589
Query: 565 RLFPLIQAMHPTLAGKITGMLLEIDNSELLHMLESPESLRSKVDEAVAVLQAHQA-KEAA 623
RLFPLIQ MH LAGKITGMLLEIDNSELLHMLESPESLRSKVDEAVAVLQAH A KEAA
Sbjct: 590 RLFPLIQTMHSNLAGKITGMLLEIDNSELLHMLESPESLRSKVDEAVAVLQAHHAKKEAA 649
Query: 624 QK--AVNSAT 631
QK AV +AT
Sbjct: 650 QKVGAVAAAT 659
>gi|185135971 poly(A)-binding protein, cytoplasmic 1-like [Homo
sapiens]
Length = 614
Score = 847 bits (2189), Expect = 0.0
Identities = 432/622 (69%), Positives = 501/622 (80%), Gaps = 16/622 (2%)
Query: 1 MNPSAPSYPMASLYVGDLHPDVTEAMLYEKFSPAGPILSIRVCRDMITRRSLGYAYVNFQ 60
MN S YP+ASLYVGDLHPDVTEAMLYEKFSPAGPILSIRVCRD+ TRRSLGYAY+NFQ
Sbjct: 1 MNASGSGYPLASLYVGDLHPDVTEAMLYEKFSPAGPILSIRVCRDVATRRSLGYAYINFQ 60
Query: 61 QPADAERALDTMNFDVIKGKPVRIMWSQRDPSLRKSGVGNIFIKNLDKSIDNKALYDTFS 120
QPADAERALDTMNF+++KG+P+RIMWSQRDP LRKSGVGNIFIKNL+ SIDNKALYDTFS
Sbjct: 61 QPADAERALDTMNFEMLKGQPIRIMWSQRDPGLRKSGVGNIFIKNLEDSIDNKALYDTFS 120
Query: 121 AFGNILSCKVVCDENGSKGYGFVHFETQEAAERAIEKMNGMLLNDRKVFVGRFKSRKERE 180
FGNILSCKV CDE+GS+G+GFVHFET EAA++AI MNGMLLNDRKVFVG FKSR+ERE
Sbjct: 121 TFGNILSCKVACDEHGSRGFGFVHFETHEAAQQAINTMNGMLLNDRKVFVGHFKSRRERE 180
Query: 181 AELGARAKEFTNVYIKNFGEDMDDERLKDLFGKFGPALSVKVMTDESGKSKGFGFVSFER 240
AELGARA EFTN+Y+KN D+D++ L+DLF +FG LSVKVM D SG S+ FGFV+FE+
Sbjct: 181 AELGARALEFTNIYVKNLPVDVDEQGLQDLFSQFGKMLSVKVMRDNSGHSRCFGFVNFEK 240
Query: 241 HEDAQKAVDEMNGKELNGKQIYVGRAQKKVERQTELKRKFEQMKQDRITRYQGVNLYVKN 300
HE+AQKAV MNGKE++G+ +Y GRAQK+VERQ ELKR+FEQMKQDR+ RYQGVNLYVKN
Sbjct: 241 HEEAQKAVVHMNGKEVSGRLLYAGRAQKRVERQNELKRRFEQMKQDRLRRYQGVNLYVKN 300
Query: 301 LDDGIDDERLRKEFSPFGTITSAKVMMEGGRSKGFGFVCFSSPEEATKAVTEMNGRIVAT 360
LDD IDD++LRKEFSP+G ITSAKVM EGG SKGFGFVCFSSPEEATKAVTEMNGRIV T
Sbjct: 301 LDDSIDDDKLRKEFSPYGVITSAKVMTEGGHSKGFGFVCFSSPEEATKAVTEMNGRIVGT 360
Query: 361 KPLYVALAQRKEERQAHLTNQYMQRMASVRAVPNPVINPYQPAPPSGYFMAAIPQTQNRA 420
KPLYVALAQRKEER+A LTNQYMQR++++R + NP++ +Q PS YF+ A+PQ +A
Sbjct: 361 KPLYVALAQRKEERKAILTNQYMQRLSTMRTLSNPLLGSFQ--QPSSYFLPAMPQPPAQA 418
Query: 421 AYYPPSQIAQLRPSPRWTAQGARPHPFQNMPGAIRPAAPRPPFSTMRPASSQVPR-VMST 479
AYY + +P+PRWT+Q RP + + P P S++R AS+QVPR V T
Sbjct: 419 AYYGCGPVTPTQPAPRWTSQPPRPSCASMVRPPVVPRRPPAHISSVRQASTQVPRTVPHT 478
Query: 480 QRVANTSTQTMGPRPAAAAAAATPAVRTVPQYKYAAGVRNPQQHLNAQPQVTMQQPAVHV 539
QRVAN TQT GP + TP +P +A A +Q+PAVH+
Sbjct: 479 QRVANIGTQTTGP---SGVGCCTPGRPLLPCKCSSA----------AHSTYRVQEPAVHI 525
Query: 540 QGQEPLTASMLASAPPQEQKQMLGERLFPLIQAMHPTLAGKITGMLLEIDNSELLHMLES 599
GQEPLTASMLA+AP EQKQM+GERL+PLI +H LAGKITGMLLEIDNSELL MLES
Sbjct: 526 PGQEPLTASMLAAAPLHEQKQMIGERLYPLIHDVHTQLAGKITGMLLEIDNSELLLMLES 585
Query: 600 PESLRSKVDEAVAVLQAHQAKE 621
PESL +K+DEAVAVLQAHQA E
Sbjct: 586 PESLHAKIDEAVAVLQAHQAME 607
>gi|168229150 poly(A) binding protein, cytoplasmic 4-like [Homo
sapiens]
Length = 370
Score = 546 bits (1406), Expect = e-155
Identities = 265/366 (72%), Positives = 313/366 (85%)
Query: 5 APSYPMASLYVGDLHPDVTEAMLYEKFSPAGPILSIRVCRDMITRRSLGYAYVNFQQPAD 64
A Y MASLYVGDLH DVTE +L+ KFS GP+LSIR+CRD +TRRSLGYAYVNF Q AD
Sbjct: 4 AAKYRMASLYVGDLHADVTEDLLFRKFSTVGPVLSIRICRDQVTRRSLGYAYVNFLQLAD 63
Query: 65 AERALDTMNFDVIKGKPVRIMWSQRDPSLRKSGVGNIFIKNLDKSIDNKALYDTFSAFGN 124
A++ALDTMNFD+IKGK +R+MWSQRD LR+SG+GN+FIKNLDKSIDNK LY+ FSAFG
Sbjct: 64 AQKALDTMNFDIIKGKSIRLMWSQRDAYLRRSGIGNVFIKNLDKSIDNKTLYEHFSAFGK 123
Query: 125 ILSCKVVCDENGSKGYGFVHFETQEAAERAIEKMNGMLLNDRKVFVGRFKSRKEREAELG 184
ILS KV+ D+ GSKGY FVHF+ Q AA+RAIE+MNG LL KVFVGRFK+RK+REAEL
Sbjct: 124 ILSSKVMSDDQGSKGYAFVHFQNQSAADRAIEEMNGKLLKGCKVFVGRFKNRKDREAELR 183
Query: 185 ARAKEFTNVYIKNFGEDMDDERLKDLFGKFGPALSVKVMTDESGKSKGFGFVSFERHEDA 244
++A EFTNVYIKNFG DMDDERLKD+F K+G LSVKVMTD SGKSKGFGFVSF+ HE A
Sbjct: 184 SKASEFTNVYIKNFGGDMDDERLKDVFSKYGKTLSVKVMTDSSGKSKGFGFVSFDSHEAA 243
Query: 245 QKAVDEMNGKELNGKQIYVGRAQKKVERQTELKRKFEQMKQDRITRYQGVNLYVKNLDDG 304
+KAV+EMNG+++NG+ I+VGRAQKKVERQ ELK+ FEQ+K++RI QGV LY+KNLDD
Sbjct: 244 KKAVEEMNGRDINGQLIFVGRAQKKVERQAELKQMFEQLKRERIRGCQGVKLYIKNLDDT 303
Query: 305 IDDERLRKEFSPFGTITSAKVMMEGGRSKGFGFVCFSSPEEATKAVTEMNGRIVATKPLY 364
IDDE+LR EFS FG+I+ KVM E G+SKGFG +CFSSPE+ATKA+TEMNGRI+ +KPL
Sbjct: 304 IDDEKLRNEFSSFGSISRVKVMQEEGQSKGFGLICFSSPEDATKAMTEMNGRILGSKPLS 363
Query: 365 VALAQR 370
+ALAQR
Sbjct: 364 IALAQR 369
Score = 179 bits (454), Expect = 7e-45
Identities = 107/293 (36%), Positives = 167/293 (56%), Gaps = 20/293 (6%)
Query: 95 KSGVGNIFIKNLDKSIDNKALYDTFSAFGNILSCKVVCDE--NGSKGYGFVHFETQEAAE 152
K + ++++ +L + L+ FS G +LS ++ D+ S GY +V+F A+
Sbjct: 6 KYRMASLYVGDLHADVTEDLLFRKFSTVGPVLSIRICRDQVTRRSLGYAYVNFLQLADAQ 65
Query: 153 RAIEKMNGMLLNDRKVFVGRFKSRKEREAELGARAKEFTNVYIKNFGEDMDDERLKDLFG 212
+A++ MN ++ + + + +R+A L R NV+IKN + +D++ L + F
Sbjct: 66 KALDTMNFDIIKGKSIRL----MWSQRDAYL--RRSGIGNVFIKNLDKSIDNKTLYEHFS 119
Query: 213 KFGPALSVKVMTDESGKSKGFGFVSFERHEDAQKAVDEMNGKELNGKQIYVGRAQKKVER 272
FG LS KVM+D+ G SKG+ FV F+ A +A++EMNGK L G +++VGR + + +R
Sbjct: 120 AFGKILSSKVMSDDQG-SKGYAFVHFQNQSAADRAIEEMNGKLLKGCKVFVGRFKNRKDR 178
Query: 273 QTELKRKFEQMKQDRITRYQGVNLYVKNLDDGIDDERLRKEFSPFGTITSAKVMMEG-GR 331
+ EL+ K + N+Y+KN +DDERL+ FS +G S KVM + G+
Sbjct: 179 EAELRSKASEF----------TNVYIKNFGGDMDDERLKDVFSKYGKTLSVKVMTDSSGK 228
Query: 332 SKGFGFVCFSSPEEATKAVTEMNGRIVATKPLYVALAQRKEERQAHLTNQYMQ 384
SKGFGFV F S E A KAV EMNGR + + ++V AQ+K ERQA L + Q
Sbjct: 229 SKGFGFVSFDSHEAAKKAVEEMNGRDINGQLIFVGRAQKKVERQAELKQMFEQ 281
>gi|18201888 poly(A) binding protein, cytoplasmic 5 [Homo sapiens]
Length = 382
Score = 480 bits (1236), Expect = e-135
Identities = 238/365 (65%), Positives = 296/365 (81%), Gaps = 1/365 (0%)
Query: 8 YPMASLYVGDLHPDVTEAMLYEKFSPAGPILSIRVCRDMITRRSLGYAYVNFQQPADAER 67
Y A+LYVGDL PDVTE MLY+KF PAGP+ R+CRD +TR LGY YVNF+ PADAE
Sbjct: 15 YLKAALYVGDLDPDVTEDMLYKKFRPAGPLRFTRICRDPVTRSPLGYGYVNFRFPADAEW 74
Query: 68 ALDTMNFDVIKGKPVRIMWSQRDPSLRKSGVGNIFIKNLDKSIDNKALYDTFSAFGNILS 127
AL+TMNFD+I GKP R+MWSQ D LRKSGVGNIFIKNLDKSIDN+AL+ FSAFGNILS
Sbjct: 75 ALNTMNFDLINGKPFRLMWSQPDDRLRKSGVGNIFIKNLDKSIDNRALFYLFSAFGNILS 134
Query: 128 CKVVCDENGSKGYGFVHFETQEAAERAIEKMNGMLLNDRKVFVGRFKSRKEREAELGARA 187
CKVVCD+NGSKGY +VHF++ AA RAI MNG+ LN+R+V+VGRFK +ER AE+ R
Sbjct: 135 CKVVCDDNGSKGYAYVHFDSLAAANRAIWHMNGVRLNNRQVYVGRFKFPEERAAEVRTRD 194
Query: 188 K-EFTNVYIKNFGEDMDDERLKDLFGKFGPALSVKVMTDESGKSKGFGFVSFERHEDAQK 246
+ FTNV++KN G+D+DDE+LK+LF ++GP SVKV+ D SGKSKGFGFV +E HE AQK
Sbjct: 195 RATFTNVFVKNIGDDIDDEKLKELFCEYGPTESVKVIRDASGKSKGFGFVRYETHEAAQK 254
Query: 247 AVDEMNGKELNGKQIYVGRAQKKVERQTELKRKFEQMKQDRITRYQGVNLYVKNLDDGID 306
AV +++GK ++GK +YVGRAQKK+ER EL+R+FE+++ +R GV +Y+KNLD+ I+
Sbjct: 255 AVLDLHGKSIDGKVLYVGRAQKKIERLAELRRRFERLRLKEKSRPPGVPIYIKNLDETIN 314
Query: 307 DERLRKEFSPFGTITSAKVMMEGGRSKGFGFVCFSSPEEATKAVTEMNGRIVATKPLYVA 366
DE+L++EFS FG+I+ AKVMME G+ KGFG VCFSS EEATKAV EMNGRIV +KPL+V
Sbjct: 315 DEKLKEEFSSFGSISRAKVMMEVGQGKGFGVVCFSSFEEATKAVDEMNGRIVGSKPLHVT 374
Query: 367 LAQRK 371
L Q +
Sbjct: 375 LGQAR 379
Score = 155 bits (393), Expect = 8e-38
Identities = 102/285 (35%), Positives = 156/285 (54%), Gaps = 19/285 (6%)
Query: 101 IFIKNLDKSIDNKALYDTFSAFGNILSCKVVCDE--NGSKGYGFVHFETQEAAERAIEKM 158
+++ +LD + LY F G + ++ D GYG+V+F AE A+ M
Sbjct: 20 LYVGDLDPDVTEDMLYKKFRPAGPLRFTRICRDPVTRSPLGYGYVNFRFPADAEWALNTM 79
Query: 159 NGMLLNDRKVFVGRFKSRKEREAELGARAKEFTNVYIKNFGEDMDDERLKDLFGKFGPAL 218
N L+N K F + +R + G N++IKN + +D+ L LF FG L
Sbjct: 80 NFDLING-KPFRLMWSQPDDRLRKSGVG-----NIFIKNLDKSIDNRALFYLFSAFGNIL 133
Query: 219 SVKVMTDESGKSKGFGFVSFERHEDAQKAVDEMNGKELNGKQIYVGRAQKKVERQTELKR 278
S KV+ D++G SKG+ +V F+ A +A+ MNG LN +Q+YVGR + ER E++
Sbjct: 134 SCKVVCDDNG-SKGYAYVHFDSLAAANRAIWHMNGVRLNNRQVYVGRFKFPEERAAEVRT 192
Query: 279 KFEQMKQDRITRYQGVNLYVKNLDDGIDDERLRKEFSPFGTITSAKVMMEG-GRSKGFGF 337
+ DR T N++VKN+ D IDDE+L++ F +G S KV+ + G+SKGFGF
Sbjct: 193 R------DRATF---TNVFVKNIGDDIDDEKLKELFCEYGPTESVKVIRDASGKSKGFGF 243
Query: 338 VCFSSPEEATKAVTEMNGRIVATKPLYVALAQRKEERQAHLTNQY 382
V + + E A KAV +++G+ + K LYV AQ+K ER A L ++
Sbjct: 244 VRYETHEAAQKAVLDLHGKSIDGKVLYVGRAQKKIERLAELRRRF 288
Score = 78.2 bits (191), Expect = 2e-14
Identities = 51/183 (27%), Positives = 99/183 (54%), Gaps = 19/183 (10%)
Query: 12 SLYVGDLHPDVTEAMLYEKFSPAGPILSIRVCRDMITRRSLGYAYVNFQQPADAERALDT 71
+++V ++ D+ + L E F GP S++V RD + +S G+ +V ++ A++A+
Sbjct: 200 NVFVKNIGDDIDDEKLKELFCEYGPTESVKVIRDA-SGKSKGFGFVRYETHEAAQKAVLD 258
Query: 72 MNFDVIKGKPVRIMWSQRD-----------------PSLRKSGVGNIFIKNLDKSIDNKA 114
++ I GK + + +Q+ R GV I+IKNLD++I+++
Sbjct: 259 LHGKSIDGKVLYVGRAQKKIERLAELRRRFERLRLKEKSRPPGVP-IYIKNLDETINDEK 317
Query: 115 LYDTFSAFGNILSCKVVCDENGSKGYGFVHFETQEAAERAIEKMNGMLLNDRKVFVGRFK 174
L + FS+FG+I KV+ + KG+G V F + E A +A+++MNG ++ + + V +
Sbjct: 318 LKEEFSSFGSISRAKVMMEVGQGKGFGVVCFSSFEEATKAVDEMNGRIVGSKPLHVTLGQ 377
Query: 175 SRK 177
+R+
Sbjct: 378 ARR 380
Score = 40.4 bits (93), Expect = 0.005
Identities = 25/100 (25%), Positives = 51/100 (51%), Gaps = 3/100 (3%)
Query: 290 RYQGVNLYVKNLDDGIDDERLRKEFSPFGTITSAKVMMEGGRSK--GFGFVCFSSPEEAT 347
+Y LYV +LD + ++ L K+F P G + ++ + G+G+V F P +A
Sbjct: 14 KYLKAALYVGDLDPDVTEDMLYKKFRPAGPLRFTRICRDPVTRSPLGYGYVNFRFPADAE 73
Query: 348 KAVTEMNGRIVATKPLYVALAQRKEE-RQAHLTNQYMQRM 386
A+ MN ++ KP + +Q + R++ + N +++ +
Sbjct: 74 WALNTMNFDLINGKPFRLMWSQPDDRLRKSGVGNIFIKNL 113
>gi|109948285 poly(A) binding protein, cytoplasmic 1-like 2B [Homo
sapiens]
Length = 200
Score = 327 bits (837), Expect = 3e-89
Identities = 157/196 (80%), Positives = 177/196 (90%)
Query: 10 MASLYVGDLHPDVTEAMLYEKFSPAGPILSIRVCRDMITRRSLGYAYVNFQQPADAERAL 69
MASLYVGDLHP+VTEAMLYEKFSPAGPILSIR+CRD ITRRSLGYAYVN+QQP DA+RAL
Sbjct: 1 MASLYVGDLHPEVTEAMLYEKFSPAGPILSIRICRDKITRRSLGYAYVNYQQPVDAKRAL 60
Query: 70 DTMNFDVIKGKPVRIMWSQRDPSLRKSGVGNIFIKNLDKSIDNKALYDTFSAFGNILSCK 129
+T+NFDVIKG+PVRIMWSQRDPSLRKSGVGN+FIKNL K+IDNKALY+ FSAFGNILSCK
Sbjct: 61 ETLNFDVIKGRPVRIMWSQRDPSLRKSGVGNVFIKNLGKTIDNKALYNIFSAFGNILSCK 120
Query: 130 VVCDENGSKGYGFVHFETQEAAERAIEKMNGMLLNDRKVFVGRFKSRKEREAELGARAKE 189
V CDE G KGYGFVHF+ QE+AERAI+ MNGM LN RK+FVGRFKS KEREAE GA A++
Sbjct: 121 VACDEKGPKGYGFVHFQKQESAERAIDVMNGMFLNYRKIFVGRFKSHKEREAERGAWARQ 180
Query: 190 FTNVYIKNFGEDMDDE 205
T+ +K+F ED D+E
Sbjct: 181 STSADVKDFEEDTDEE 196
Score = 108 bits (271), Expect = 1e-23
Identities = 64/180 (35%), Positives = 105/180 (58%), Gaps = 9/180 (5%)
Query: 98 VGNIFIKNLDKSIDNKALYDTFSAFGNILSCKVVCDE--NGSKGYGFVHFETQEAAERAI 155
+ ++++ +L + LY+ FS G ILS ++ D+ S GY +V+++ A+RA+
Sbjct: 1 MASLYVGDLHPEVTEAMLYEKFSPAGPILSIRICRDKITRRSLGYAYVNYQQPVDAKRAL 60
Query: 156 EKMNGMLLNDRKVFVGRFKSRKEREAELGARAKEFTNVYIKNFGEDMDDERLKDLFGKFG 215
E +N ++ R V + +R+ L R NV+IKN G+ +D++ L ++F FG
Sbjct: 61 ETLNFDVIKGRPVRI----MWSQRDPSL--RKSGVGNVFIKNLGKTIDNKALYNIFSAFG 114
Query: 216 PALSVKVMTDESGKSKGFGFVSFERHEDAQKAVDEMNGKELNGKQIYVGRAQKKVERQTE 275
LS KV DE G KG+GFV F++ E A++A+D MNG LN ++I+VGR + ER+ E
Sbjct: 115 NILSCKVACDEKGP-KGYGFVHFQKQESAERAIDVMNGMFLNYRKIFVGRFKSHKEREAE 173
Score = 86.7 bits (213), Expect = 6e-17
Identities = 52/187 (27%), Positives = 99/187 (52%), Gaps = 19/187 (10%)
Query: 192 NVYIKNFGEDMDDERLKDLFGKFGPALSVKVMTDE-SGKSKGFGFVSFERHEDAQKAVDE 250
++Y+ + ++ + L + F GP LS+++ D+ + +S G+ +V++++ DA++A++
Sbjct: 3 SLYVGDLHPEVTEAMLYEKFSPAGPILSIRICRDKITRRSLGYAYVNYQQPVDAKRALET 62
Query: 251 MNGKELNGKQIYVGRAQKKVERQTELKRKFEQMKQDRITRYQGV-NLYVKNLDDGIDDER 309
+N + G+ + + +Q+ D R GV N+++KNL ID++
Sbjct: 63 LNFDVIKGRPVRIMWSQR-----------------DPSLRKSGVGNVFIKNLGKTIDNKA 105
Query: 310 LRKEFSPFGTITSAKVMMEGGRSKGFGFVCFSSPEEATKAVTEMNGRIVATKPLYVALAQ 369
L FS FG I S KV + KG+GFV F E A +A+ MNG + + ++V +
Sbjct: 106 LYNIFSAFGNILSCKVACDEKGPKGYGFVHFQKQESAERAIDVMNGMFLNYRKIFVGRFK 165
Query: 370 RKEERQA 376
+ER+A
Sbjct: 166 SHKEREA 172
Score = 44.3 bits (103), Expect = 3e-04
Identities = 25/72 (34%), Positives = 39/72 (54%), Gaps = 2/72 (2%)
Query: 2 NPSAPSYPMASLYVGDLHPDVTEAMLYEKFSPAGPILSIRVCRDMITRRSLGYAYVNFQQ 61
+PS + ++++ +L + LY FS G ILS +V D + GY +V+FQ+
Sbjct: 81 DPSLRKSGVGNVFIKNLGKTIDNKALYNIFSAFGNILSCKVACD--EKGPKGYGFVHFQK 138
Query: 62 PADAERALDTMN 73
AERA+D MN
Sbjct: 139 QESAERAIDVMN 150
>gi|61175237 poly(A) binding protein, cytoplasmic 1-like 2A [Homo
sapiens]
Length = 200
Score = 327 bits (837), Expect = 3e-89
Identities = 157/196 (80%), Positives = 177/196 (90%)
Query: 10 MASLYVGDLHPDVTEAMLYEKFSPAGPILSIRVCRDMITRRSLGYAYVNFQQPADAERAL 69
MASLYVGDLHP+VTEAMLYEKFSPAGPILSIR+CRD ITRRSLGYAYVN+QQP DA+RAL
Sbjct: 1 MASLYVGDLHPEVTEAMLYEKFSPAGPILSIRICRDKITRRSLGYAYVNYQQPVDAKRAL 60
Query: 70 DTMNFDVIKGKPVRIMWSQRDPSLRKSGVGNIFIKNLDKSIDNKALYDTFSAFGNILSCK 129
+T+NFDVIKG+PVRIMWSQRDPSLRKSGVGN+FIKNL K+IDNKALY+ FSAFGNILSCK
Sbjct: 61 ETLNFDVIKGRPVRIMWSQRDPSLRKSGVGNVFIKNLGKTIDNKALYNIFSAFGNILSCK 120
Query: 130 VVCDENGSKGYGFVHFETQEAAERAIEKMNGMLLNDRKVFVGRFKSRKEREAELGARAKE 189
V CDE G KGYGFVHF+ QE+AERAI+ MNGM LN RK+FVGRFKS KEREAE GA A++
Sbjct: 121 VACDEKGPKGYGFVHFQKQESAERAIDVMNGMFLNYRKIFVGRFKSHKEREAERGAWARQ 180
Query: 190 FTNVYIKNFGEDMDDE 205
T+ +K+F ED D+E
Sbjct: 181 STSADVKDFEEDTDEE 196
Score = 108 bits (271), Expect = 1e-23
Identities = 64/180 (35%), Positives = 105/180 (58%), Gaps = 9/180 (5%)
Query: 98 VGNIFIKNLDKSIDNKALYDTFSAFGNILSCKVVCDE--NGSKGYGFVHFETQEAAERAI 155
+ ++++ +L + LY+ FS G ILS ++ D+ S GY +V+++ A+RA+
Sbjct: 1 MASLYVGDLHPEVTEAMLYEKFSPAGPILSIRICRDKITRRSLGYAYVNYQQPVDAKRAL 60
Query: 156 EKMNGMLLNDRKVFVGRFKSRKEREAELGARAKEFTNVYIKNFGEDMDDERLKDLFGKFG 215
E +N ++ R V + +R+ L R NV+IKN G+ +D++ L ++F FG
Sbjct: 61 ETLNFDVIKGRPVRI----MWSQRDPSL--RKSGVGNVFIKNLGKTIDNKALYNIFSAFG 114
Query: 216 PALSVKVMTDESGKSKGFGFVSFERHEDAQKAVDEMNGKELNGKQIYVGRAQKKVERQTE 275
LS KV DE G KG+GFV F++ E A++A+D MNG LN ++I+VGR + ER+ E
Sbjct: 115 NILSCKVACDEKGP-KGYGFVHFQKQESAERAIDVMNGMFLNYRKIFVGRFKSHKEREAE 173
Score = 86.7 bits (213), Expect = 6e-17
Identities = 52/187 (27%), Positives = 99/187 (52%), Gaps = 19/187 (10%)
Query: 192 NVYIKNFGEDMDDERLKDLFGKFGPALSVKVMTDE-SGKSKGFGFVSFERHEDAQKAVDE 250
++Y+ + ++ + L + F GP LS+++ D+ + +S G+ +V++++ DA++A++
Sbjct: 3 SLYVGDLHPEVTEAMLYEKFSPAGPILSIRICRDKITRRSLGYAYVNYQQPVDAKRALET 62
Query: 251 MNGKELNGKQIYVGRAQKKVERQTELKRKFEQMKQDRITRYQGV-NLYVKNLDDGIDDER 309
+N + G+ + + +Q+ D R GV N+++KNL ID++
Sbjct: 63 LNFDVIKGRPVRIMWSQR-----------------DPSLRKSGVGNVFIKNLGKTIDNKA 105
Query: 310 LRKEFSPFGTITSAKVMMEGGRSKGFGFVCFSSPEEATKAVTEMNGRIVATKPLYVALAQ 369
L FS FG I S KV + KG+GFV F E A +A+ MNG + + ++V +
Sbjct: 106 LYNIFSAFGNILSCKVACDEKGPKGYGFVHFQKQESAERAIDVMNGMFLNYRKIFVGRFK 165
Query: 370 RKEERQA 376
+ER+A
Sbjct: 166 SHKEREA 172
Score = 44.3 bits (103), Expect = 3e-04
Identities = 25/72 (34%), Positives = 39/72 (54%), Gaps = 2/72 (2%)
Query: 2 NPSAPSYPMASLYVGDLHPDVTEAMLYEKFSPAGPILSIRVCRDMITRRSLGYAYVNFQQ 61
+PS + ++++ +L + LY FS G ILS +V D + GY +V+FQ+
Sbjct: 81 DPSLRKSGVGNVFIKNLGKTIDNKALYNIFSAFGNILSCKVACD--EKGPKGYGFVHFQK 138
Query: 62 PADAERALDTMN 73
AERA+D MN
Sbjct: 139 QESAERAIDVMN 150
>gi|239753150 PREDICTED: similar to poly(A) binding protein,
cytoplasmic 1 [Homo sapiens]
Length = 94
Score = 147 bits (372), Expect = 2e-35
Identities = 77/85 (90%), Positives = 80/85 (94%)
Query: 549 MLASAPPQEQKQMLGERLFPLIQAMHPTLAGKITGMLLEIDNSELLHMLESPESLRSKVD 608
MLASAPPQEQK++LGERLFPLIQAMHPTLAGKITGM LE DNSELLHMLESPESL SKV
Sbjct: 1 MLASAPPQEQKRILGERLFPLIQAMHPTLAGKITGMWLETDNSELLHMLESPESLHSKVV 60
Query: 609 EAVAVLQAHQAKEAAQKAVNSATGV 633
EAVAVLQAH+AKEAAQKAVNSAT V
Sbjct: 61 EAVAVLQAHRAKEAAQKAVNSATAV 85
>gi|5032069 splicing factor 3b, subunit 4 [Homo sapiens]
Length = 424
Score = 121 bits (303), Expect = 2e-27
Identities = 72/183 (39%), Positives = 106/183 (57%), Gaps = 7/183 (3%)
Query: 11 ASLYVGDLHPDVTEAMLYEKFSPAGPILSIRVCRDMITRRSLGYAYVNFQQPADAERALD 70
A++YVG L V+E +L+E F AGP+++ + +D +T + GY +V F DA+ A+
Sbjct: 13 ATVYVGGLDEKVSEPLLWELFLQAGPVVNTHMPKDRVTGQHQGYGFVEFLSEEDADYAIK 72
Query: 71 TMNFDVIKGKPVRIMWSQRDPSLRKSGVG-NIFIKNLDKSIDNKALYDTFSAFGNILSCK 129
MN + GKP+R+ ++ + VG NIFI NLD ID K LYDTFSAFG IL
Sbjct: 73 IMNMIKLYGKPIRV--NKASAHNKNLDVGANIFIGNLDPEIDEKLLYDTFSAFGVILQTP 130
Query: 130 VVC---DENGSKGYGFVHFETQEAAERAIEKMNGMLLNDRKVFVGRFKSRKEREAELGAR 186
+ D SKGY F++F + +A++ AIE MNG L +R + V + +K+ + E
Sbjct: 131 KIMRDPDTGNSKGYAFINFASFDASDAAIEAMNGQYLCNRPITVS-YAFKKDSKGERHGS 189
Query: 187 AKE 189
A E
Sbjct: 190 AAE 192
Score = 98.6 bits (244), Expect = 2e-20
Identities = 84/316 (26%), Positives = 128/316 (40%), Gaps = 56/316 (17%)
Query: 193 VYIKNFGEDMDDERLKDLFGKFGPALSVKVMTDE-SGKSKGFGFVSFERHEDAQKAVDEM 251
VY+ E + + L +LF + GP ++ + D +G+ +G+GFV F EDA A+ M
Sbjct: 15 VYVGGLDEKVSEPLLWELFLQAGPVVNTHMPKDRVTGQHQGYGFVEFLSEEDADYAIKIM 74
Query: 252 NGKELNGKQIYVGRAQKKVERQTELKRKFEQMKQDRITRYQGVNLYVKNLDDGIDDERLR 311
N +L GK I V +A + G N+++ NLD ID++ L
Sbjct: 75 NMIKLYGKPIRVNKASAHNKNLDV-----------------GANIFIGNLDPEIDEKLLY 117
Query: 312 KEFSPFGTITSAKVMM---EGGRSKGFGFVCFSSPEEATKAVTEMNGRIVATKPLYVALA 368
FS FG I +M + G SKG+ F+ F+S + + A+ MNG+ + +P+ V+ A
Sbjct: 118 DTFSAFGVILQTPKIMRDPDTGNSKGYAFINFASFDASDAAIEAMNGQYLCNRPITVSYA 177
Query: 369 QRKEER-------------------QAHLTNQYMQRMASVRAVPNPVIN------PYQPA 403
+K+ + QA +Q + PNPV++ P
Sbjct: 178 FKKDSKGERHGSAAERLLAAQNPLSQADRPHQLFADAPPPPSAPNPVVSSLGSGLPPPGM 237
Query: 404 PPSGYFMAAIPQTQNRAAYYPPSQIAQLRPSPRWTAQGARPHPFQNMPGAIRPA------ 457
PP G F +P PP + P P P PGA P
Sbjct: 238 PPPGSFPPPVPP----PGALPPGIPPAMPPPPMPPGAAGHGPPSAGTPGAGHPGHGHSHP 293
Query: 458 APRPPFSTMRPASSQV 473
P PP P SQ+
Sbjct: 294 HPFPPGGMPHPGMSQM 309
Score = 81.3 bits (199), Expect = 3e-15
Identities = 53/183 (28%), Positives = 96/183 (52%), Gaps = 11/183 (6%)
Query: 91 PSLRKSGVGNIFIKNLDKSIDNKALYDTFSAFGNILSCKVVCDE--NGSKGYGFVHFETQ 148
P ++ +++ LD+ + L++ F G +++ + D +GYGFV F ++
Sbjct: 5 PISERNQDATVYVGGLDEKVSEPLLWELFLQAGPVVNTHMPKDRVTGQHQGYGFVEFLSE 64
Query: 149 EAAERAIEKMNGMLLNDRKVFVGRFKSRKEREAELGARAKEFTNVYIKNFGEDMDDERLK 208
E A+ AI+ MN + L + + V + S + ++GA N++I N ++D++ L
Sbjct: 65 EDADYAIKIMNMIKLYGKPIRVNK-ASAHNKNLDVGA------NIFIGNLDPEIDEKLLY 117
Query: 209 DLFGKFGPALSV-KVMTD-ESGKSKGFGFVSFERHEDAQKAVDEMNGKELNGKQIYVGRA 266
D F FG L K+M D ++G SKG+ F++F + + A++ MNG+ L + I V A
Sbjct: 118 DTFSAFGVILQTPKIMRDPDTGNSKGYAFINFASFDASDAAIEAMNGQYLCNRPITVSYA 177
Query: 267 QKK 269
KK
Sbjct: 178 FKK 180
>gi|38201714 ELAV-like 1 [Homo sapiens]
Length = 326
Score = 119 bits (298), Expect = 8e-27
Identities = 85/318 (26%), Positives = 150/318 (47%), Gaps = 49/318 (15%)
Query: 97 GVGNIFIKNLDKSIDNKALYDTFSAFGNILSCKVVCDE--NGSKGYGFVHFETQEAAERA 154
G N+ + L +++ L FS+ G + S K++ D+ S GYGFV++ T + AERA
Sbjct: 18 GRTNLIVNYLPQNMTQDELRSLFSSIGEVESAKLIRDKVAGHSLGYGFVNYVTAKDAERA 77
Query: 155 IEKMNGMLLNDRKVFVGRFKSRKEREAELGARAKEFTNVYIKNFGEDMDDERLKDLFGKF 214
I +NG+ L + + K A + + N+YI M + ++D+F +F
Sbjct: 78 INTLNGLRLQSKTI--------KVSYARPSSEVIKDANLYISGLPRTMTQKDVEDMFSRF 129
Query: 215 GPALSVKVMTDE-SGKSKGFGFVSFERHEDAQKAVDEMNGKELNG--------------- 258
G ++ +V+ D+ +G S+G F+ F++ +A++A+ NG + G
Sbjct: 130 GRIINSRVLVDQTTGLSRGVAFIRFDKRSEAEEAITSFNGHKPPGSSEPITVKFAANPNQ 189
Query: 259 -------KQIYVGRAQK---KVERQTELKRKFEQMKQDRITRYQGVN----------LYV 298
Q+Y A++ V Q + + +F M D ++ GVN +++
Sbjct: 190 NKNVALLSQLYHSPARRFGGPVHHQAQ-RFRFSPMGVDHMSGLSGVNVPGNASSGWCIFI 248
Query: 299 KNLDDGIDDERLRKEFSPFGTITSAKVMME--GGRSKGFGFVCFSSPEEATKAVTEMNGR 356
NL D+ L + F PFG +T+ KV+ + + KGFGFV ++ EEA A+ +NG
Sbjct: 249 YNLGQDADEGILWQMFGPFGAVTNVKVIRDFNTNKCKGFGFVTMTNYEEAAMAIASLNGY 308
Query: 357 IVATKPLYVALAQRKEER 374
+ K L V+ K +
Sbjct: 309 RLGDKILQVSFKTNKSHK 326
Score = 87.8 bits (216), Expect = 3e-17
Identities = 49/151 (32%), Positives = 85/151 (56%), Gaps = 4/151 (2%)
Query: 12 SLYVGDLHPDVTEAMLYEKFSPAGPILSIRVCRDMITRRSLGYAYVNFQQPADAERALDT 71
+L V L ++T+ L FS G + S ++ RD + SLGY +VN+ DAERA++T
Sbjct: 21 NLIVNYLPQNMTQDELRSLFSSIGEVESAKLIRDKVAGHSLGYGFVNYVTAKDAERAINT 80
Query: 72 MNFDVIKGKPVRIMWSQRDPSLRKSGVGNIFIKNLDKSIDNKALYDTFSAFGNILSCKVV 131
+N ++ K +++ +++ PS N++I L +++ K + D FS FG I++ +V+
Sbjct: 81 LNGLRLQSKTIKVSYAR--PSSEVIKDANLYISGLPRTMTQKDVEDMFSRFGRIINSRVL 138
Query: 132 CDENG--SKGYGFVHFETQEAAERAIEKMNG 160
D+ S+G F+ F+ + AE AI NG
Sbjct: 139 VDQTTGLSRGVAFIRFDKRSEAEEAITSFNG 169
Score = 64.3 bits (155), Expect = 3e-10
Identities = 63/231 (27%), Positives = 96/231 (41%), Gaps = 55/231 (23%)
Query: 3 PSAPSYPMASLYVGDLHPDVTEAMLYEKFSPAGPILSIRVCRDMITRRSLGYAYVNFQQP 62
PS+ A+LY+ L +T+ + + FS G I++ RV D T S G A++ F +
Sbjct: 98 PSSEVIKDANLYISGLPRTMTQKDVEDMFSRFGRIINSRVLVDQTTGLSRGVAFIRFDKR 157
Query: 63 ADAERALDTMNFDVIKG--KPVRIMWSQRDPSLRK------------------------- 95
++AE A+ + N G +P+ + ++ +P+ K
Sbjct: 158 SEAEEAITSFNGHKPPGSSEPITVKFA-ANPNQNKNVALLSQLYHSPARRFGGPVHHQAQ 216
Query: 96 ---------------SGV---GN------IFIKNLDKSIDNKALYDTFSAFGNILSCKVV 131
SGV GN IFI NL + D L+ F FG + + KV+
Sbjct: 217 RFRFSPMGVDHMSGLSGVNVPGNASSGWCIFIYNLGQDADEGILWQMFGPFGAVTNVKVI 276
Query: 132 CD--ENGSKGYGFVHFETQEAAERAIEKMNGMLLNDRKVFVGRFKSRKERE 180
D N KG+GFV E A AI +NG L D K+ FK+ K +
Sbjct: 277 RDFNTNKCKGFGFVTMTNYEEAAMAIASLNGYRLGD-KILQVSFKTNKSHK 326
>gi|188219591 TIA1 protein isoform 2 [Homo sapiens]
Length = 386
Score = 119 bits (297), Expect = 1e-26
Identities = 73/270 (27%), Positives = 132/270 (48%), Gaps = 16/270 (5%)
Query: 101 IFIKNLDKSIDNKALYDTFSAFGNILSCKVVCDENGSKGYGFVHFETQEAAERAIEKMNG 160
+++ NL + + + FS G +CK++ D G+ Y FV F A A+ MNG
Sbjct: 9 LYVGNLSRDVTEALILQLFSQIGPCKNCKMIMDTAGNDPYCFVEFHEHRHAAAALAAMNG 68
Query: 161 MLLNDRKVFVGRFKSRKEREAELGA-------RAKEFTNVYIKNFGEDMDDERLKDLFGK 213
+ ++V V + ++ + + R+++ +V++ + ++ E +K F
Sbjct: 69 RKIMGKEVKVNWATTPSSQKKDTSSSTVVSTQRSQDHFHVFVGDLSPEITTEDIKAAFAP 128
Query: 214 FGPALSVKVMTD-ESGKSKGFGFVSFERHEDAQKAVDEMNGKELNGKQIYVGRAQKKVER 272
FG +V+ D +GKSKG+GFVSF DA+ A+ +M G+ L G+QI A +K
Sbjct: 129 FGRISDARVVKDMATGKSKGYGFVSFFNKWDAENAIQQMGGQWLGGRQIRTNWATRKPPA 188
Query: 273 -QTELKRKFEQMKQDRITRY---QGVNLYVKNLDDGIDDERLRKEFSPFGTITSAKVMME 328
++ + +Q+ D + +Y + G+ ++ +R+ FSPFG I +V +
Sbjct: 189 PKSTYESNTKQLSYDEVVNQSSPSNCTVYCGGVTSGLTEQLMRQTFSPFGQIMEIRVFPD 248
Query: 329 GGRSKGFGFVCFSSPEEATKAVTEMNGRIV 358
KG+ FV F+S E A A+ +NG +
Sbjct: 249 ----KGYSFVRFNSHESAAHAIVSVNGTTI 274
Score = 105 bits (262), Expect = 1e-22
Identities = 77/276 (27%), Positives = 124/276 (44%), Gaps = 36/276 (13%)
Query: 12 SLYVGDLHPDVTEAMLYEKFSPAGPILSIRVCRDMITRRSLGYAYVNFQQPADAERALDT 71
+LYVG+L DVTEA++ + FS GP + ++ D T + Y +V F + A AL
Sbjct: 8 TLYVGNLSRDVTEALILQLFSQIGPCKNCKMIMD--TAGNDPYCFVEFHEHRHAAAALAA 65
Query: 72 MNFDVIKGKPVRIMWSQRDPSLRKSGVG-------------NIFIKNLDKSIDNKALYDT 118
MN I GK V++ W+ S +K ++F+ +L I + +
Sbjct: 66 MNGRKIMGKEVKVNWATTPSSQKKDTSSSTVVSTQRSQDHFHVFVGDLSPEITTEDIKAA 125
Query: 119 FSAFGNILSCKVVCD--ENGSKGYGFVHFETQEAAERAIEKMNGMLLNDRKVFV------ 170
F+ FG I +VV D SKGYGFV F + AE AI++M G L R++
Sbjct: 126 FAPFGRISDARVVKDMATGKSKGYGFVSFFNKWDAENAIQQMGGQWLGGRQIRTNWATRK 185
Query: 171 -----GRFKSRKER---EAELGARAKEFTNVYIKNFGEDMDDERLKDLFGKFGPALSVKV 222
++S ++ + + + VY + ++ ++ F FG + ++V
Sbjct: 186 PPAPKSTYESNTKQLSYDEVVNQSSPSNCTVYCGGVTSGLTEQLMRQTFSPFGQIMEIRV 245
Query: 223 MTDESGKSKGFGFVSFERHEDAQKAVDEMNGKELNG 258
D KG+ FV F HE A A+ +NG + G
Sbjct: 246 FPD-----KGYSFVRFNSHESAAHAIVSVNGTTIEG 276
Score = 86.7 bits (213), Expect = 6e-17
Identities = 63/251 (25%), Positives = 117/251 (46%), Gaps = 20/251 (7%)
Query: 193 VYIKNFGEDMDDERLKDLFGKFGPALSVKVMTDESGKSKGFGFVSFERHEDAQKAVDEMN 252
+Y+ N D+ + + LF + GP + K++ D +G + FV F H A A+ MN
Sbjct: 9 LYVGNLSRDVTEALILQLFSQIGPCKNCKMIMDTAGNDP-YCFVEFHEHRHAAAALAAMN 67
Query: 253 GKELNGKQIYVGRAQKKVERQTELKRKF---EQMKQDRITRYQGVNLYVKNLDDGIDDER 309
G+++ GK++ V A ++ + Q QD +++V +L I E
Sbjct: 68 GRKIMGKEVKVNWATTPSSQKKDTSSSTVVSTQRSQDHF------HVFVGDLSPEITTED 121
Query: 310 LRKEFSPFGTITSAKVM--MEGGRSKGFGFVCFSSPEEATKAVTEMNGRIVATKPLYVAL 367
++ F+PFG I+ A+V+ M G+SKG+GFV F + +A A+ +M G+ + + +
Sbjct: 122 IKAAFAPFGRISDARVVKDMATGKSKGYGFVSFFNKWDAENAIQQMGGQWLGGRQIRTNW 181
Query: 368 AQRKEERQAHLTNQYMQRMASVRAVPNPVINPYQPAPPSGY---FMAAIPQTQNRAAYYP 424
A RK ++++ + V+N P+ + Y + + + R + P
Sbjct: 182 ATRKPPAPKSTYESNTKQLSY-----DEVVNQSSPSNCTVYCGGVTSGLTEQLMRQTFSP 236
Query: 425 PSQIAQLRPSP 435
QI ++R P
Sbjct: 237 FGQIMEIRVFP 247
Score = 86.3 bits (212), Expect = 8e-17
Identities = 53/176 (30%), Positives = 81/176 (46%), Gaps = 24/176 (13%)
Query: 13 LYVGDLHPDVTEAMLYEKFSPAGPILSIRVCRDMITRRSLGYAYVNFQQPADAERALDTM 72
++VGDL P++T + F+P G I RV +DM T +S GY +V+F DAE A+ M
Sbjct: 108 VFVGDLSPEITTEDIKAAFAPFGRISDARVVKDMATGKSKGYGFVSFFNKWDAENAIQQM 167
Query: 73 NFDVIKGKPVRIMWSQRDPSLRKSGVGN--------------------IFIKNLDKSIDN 112
+ G+ +R W+ R P KS + ++ + +
Sbjct: 168 GGQWLGGRQIRTNWATRKPPAPKSTYESNTKQLSYDEVVNQSSPSNCTVYCGGVTSGLTE 227
Query: 113 KALYDTFSAFGNILSCKVVCDENGSKGYGFVHFETQEAAERAIEKMNGMLLNDRKV 168
+ + TFS FG I+ +V D KGY FV F + E+A AI +NG + V
Sbjct: 228 QLMRQTFSPFGQIMEIRVFPD----KGYSFVRFNSHESAAHAIVSVNGTTIEGHVV 279
Score = 47.4 bits (111), Expect = 4e-05
Identities = 28/88 (31%), Positives = 46/88 (52%), Gaps = 8/88 (9%)
Query: 1 MNPSAPSYPMASLYVGDLHPDVTEAMLYEKFSPAGPILSIRVCRDMITRRSLGYAYVNFQ 60
+N S+PS ++Y G + +TE ++ + FSP G I+ IRV D GY++V F
Sbjct: 206 VNQSSPSN--CTVYCGGVTSGLTEQLMRQTFSPFGQIMEIRVFPDK------GYSFVRFN 257
Query: 61 QPADAERALDTMNFDVIKGKPVRIMWSQ 88
A A+ ++N I+G V+ W +
Sbjct: 258 SHESAAHAIVSVNGTTIEGHVVKCYWGK 285
>gi|188219593 TIA1 protein isoform 1 [Homo sapiens]
Length = 375
Score = 116 bits (291), Expect = 6e-26
Identities = 72/263 (27%), Positives = 127/263 (48%), Gaps = 13/263 (4%)
Query: 101 IFIKNLDKSIDNKALYDTFSAFGNILSCKVVCDENGSKGYGFVHFETQEAAERAIEKMNG 160
+++ NL + + + FS G +CK++ D G+ Y FV F A A+ MNG
Sbjct: 9 LYVGNLSRDVTEALILQLFSQIGPCKNCKMIMDTAGNDPYCFVEFHEHRHAAAALAAMNG 68
Query: 161 MLLNDRKVFVGRFKSRKEREAELGARAKEFTNVYIKNFGEDMDDERLKDLFGKFGPALSV 220
+ ++V V + ++ + +V++ + ++ E +K F FG
Sbjct: 69 RKIMGKEVKVNWATTPSSQKKD----TSNHFHVFVGDLSPEITTEDIKAAFAPFGRISDA 124
Query: 221 KVMTD-ESGKSKGFGFVSFERHEDAQKAVDEMNGKELNGKQIYVGRAQKKVER-QTELKR 278
+V+ D +GKSKG+GFVSF DA+ A+ +M G+ L G+QI A +K ++ +
Sbjct: 125 RVVKDMATGKSKGYGFVSFFNKWDAENAIQQMGGQWLGGRQIRTNWATRKPPAPKSTYES 184
Query: 279 KFEQMKQDRITRY---QGVNLYVKNLDDGIDDERLRKEFSPFGTITSAKVMMEGGRSKGF 335
+Q+ D + +Y + G+ ++ +R+ FSPFG I +V + KG+
Sbjct: 185 NTKQLSYDEVVNQSSPSNCTVYCGGVTSGLTEQLMRQTFSPFGQIMEIRVFPD----KGY 240
Query: 336 GFVCFSSPEEATKAVTEMNGRIV 358
FV F+S E A A+ +NG +
Sbjct: 241 SFVRFNSHESAAHAIVSVNGTTI 263
Score = 110 bits (276), Expect = 3e-24
Identities = 79/266 (29%), Positives = 125/266 (46%), Gaps = 27/266 (10%)
Query: 12 SLYVGDLHPDVTEAMLYEKFSPAGPILSIRVCRDMITRRSLGYAYVNFQQPADAERALDT 71
+LYVG+L DVTEA++ + FS GP + ++ D T + Y +V F + A AL
Sbjct: 8 TLYVGNLSRDVTEALILQLFSQIGPCKNCKMIMD--TAGNDPYCFVEFHEHRHAAAALAA 65
Query: 72 MNFDVIKGKPVRIMWSQRDPSLRKSGVGN---IFIKNLDKSIDNKALYDTFSAFGNILSC 128
MN I GK V++ W+ PS +K N +F+ +L I + + F+ FG I
Sbjct: 66 MNGRKIMGKEVKVNWA-TTPSSQKKDTSNHFHVFVGDLSPEITTEDIKAAFAPFGRISDA 124
Query: 129 KVVCD--ENGSKGYGFVHFETQEAAERAIEKMNGMLLNDRKVFV-----------GRFKS 175
+VV D SKGYGFV F + AE AI++M G L R++ ++S
Sbjct: 125 RVVKDMATGKSKGYGFVSFFNKWDAENAIQQMGGQWLGGRQIRTNWATRKPPAPKSTYES 184
Query: 176 RKER---EAELGARAKEFTNVYIKNFGEDMDDERLKDLFGKFGPALSVKVMTDESGKSKG 232
++ + + + VY + ++ ++ F FG + ++V D KG
Sbjct: 185 NTKQLSYDEVVNQSSPSNCTVYCGGVTSGLTEQLMRQTFSPFGQIMEIRVFPD-----KG 239
Query: 233 FGFVSFERHEDAQKAVDEMNGKELNG 258
+ FV F HE A A+ +NG + G
Sbjct: 240 YSFVRFNSHESAAHAIVSVNGTTIEG 265
Score = 86.7 bits (213), Expect = 6e-17
Identities = 61/248 (24%), Positives = 115/248 (46%), Gaps = 25/248 (10%)
Query: 193 VYIKNFGEDMDDERLKDLFGKFGPALSVKVMTDESGKSKGFGFVSFERHEDAQKAVDEMN 252
+Y+ N D+ + + LF + GP + K++ D +G + FV F H A A+ MN
Sbjct: 9 LYVGNLSRDVTEALILQLFSQIGPCKNCKMIMDTAGNDP-YCFVEFHEHRHAAAALAAMN 67
Query: 253 GKELNGKQIYVGRAQKKVERQTELKRKFEQMKQDRITRYQGVNLYVKNLDDGIDDERLRK 312
G+++ GK++ V A ++ + F +++V +L I E ++
Sbjct: 68 GRKIMGKEVKVNWATTPSSQKKDTSNHF--------------HVFVGDLSPEITTEDIKA 113
Query: 313 EFSPFGTITSAKVM--MEGGRSKGFGFVCFSSPEEATKAVTEMNGRIVATKPLYVALAQR 370
F+PFG I+ A+V+ M G+SKG+GFV F + +A A+ +M G+ + + + A R
Sbjct: 114 AFAPFGRISDARVVKDMATGKSKGYGFVSFFNKWDAENAIQQMGGQWLGGRQIRTNWATR 173
Query: 371 KEERQAHLTNQYMQRMASVRAVPNPVINPYQPAPPSGY---FMAAIPQTQNRAAYYPPSQ 427
K ++++ + V+N P+ + Y + + + R + P Q
Sbjct: 174 KPPAPKSTYESNTKQLSY-----DEVVNQSSPSNCTVYCGGVTSGLTEQLMRQTFSPFGQ 228
Query: 428 IAQLRPSP 435
I ++R P
Sbjct: 229 IMEIRVFP 236
Score = 86.3 bits (212), Expect = 8e-17
Identities = 53/176 (30%), Positives = 81/176 (46%), Gaps = 24/176 (13%)
Query: 13 LYVGDLHPDVTEAMLYEKFSPAGPILSIRVCRDMITRRSLGYAYVNFQQPADAERALDTM 72
++VGDL P++T + F+P G I RV +DM T +S GY +V+F DAE A+ M
Sbjct: 97 VFVGDLSPEITTEDIKAAFAPFGRISDARVVKDMATGKSKGYGFVSFFNKWDAENAIQQM 156
Query: 73 NFDVIKGKPVRIMWSQRDPSLRKSGVGN--------------------IFIKNLDKSIDN 112
+ G+ +R W+ R P KS + ++ + +
Sbjct: 157 GGQWLGGRQIRTNWATRKPPAPKSTYESNTKQLSYDEVVNQSSPSNCTVYCGGVTSGLTE 216
Query: 113 KALYDTFSAFGNILSCKVVCDENGSKGYGFVHFETQEAAERAIEKMNGMLLNDRKV 168
+ + TFS FG I+ +V D KGY FV F + E+A AI +NG + V
Sbjct: 217 QLMRQTFSPFGQIMEIRVFPD----KGYSFVRFNSHESAAHAIVSVNGTTIEGHVV 268
Score = 47.4 bits (111), Expect = 4e-05
Identities = 28/88 (31%), Positives = 46/88 (52%), Gaps = 8/88 (9%)
Query: 1 MNPSAPSYPMASLYVGDLHPDVTEAMLYEKFSPAGPILSIRVCRDMITRRSLGYAYVNFQ 60
+N S+PS ++Y G + +TE ++ + FSP G I+ IRV D GY++V F
Sbjct: 195 VNQSSPSN--CTVYCGGVTSGLTEQLMRQTFSPFGQIMEIRVFPDK------GYSFVRFN 246
Query: 61 QPADAERALDTMNFDVIKGKPVRIMWSQ 88
A A+ ++N I+G V+ W +
Sbjct: 247 SHESAAHAIVSVNGTTIEGHVVKCYWGK 274
>gi|4507499 TIA-1 related protein isoform 1 [Homo sapiens]
Length = 375
Score = 115 bits (287), Expect = 2e-25
Identities = 74/263 (28%), Positives = 126/263 (47%), Gaps = 13/263 (4%)
Query: 101 IFIKNLDKSIDNKALYDTFSAFGNILSCKVVCDENGSKGYGFVHFETQEAAERAIEKMNG 160
+++ NL + + + FS G SCK++ + + Y FV F A A+ MNG
Sbjct: 11 LYVGNLSRDVTEVLILQLFSQIGPCKSCKMITEHTSNDPYCFVEFYEHRDAAAALAAMNG 70
Query: 161 MLLNDRKVFVGRFKSRKEREAELGARAKEFTNVYIKNFGEDMDDERLKDLFGKFGPALSV 220
+ ++V V + ++ + +V++ + ++ E +K F FG
Sbjct: 71 RKILGKEVKVNWATTPSSQKKD----TSNHFHVFVGDLSPEITTEDIKSAFAPFGKISDA 126
Query: 221 KVMTD-ESGKSKGFGFVSFERHEDAQKAVDEMNGKELNGKQIYVGRAQKK--VERQTELK 277
+V+ D +GKSKG+GFVSF DA+ A+ M G+ L G+QI A +K + T+
Sbjct: 127 RVVKDMATGKSKGYGFVSFYNKLDAENAIVHMGGQWLGGRQIRTNWATRKPPAPKSTQEN 186
Query: 278 RKFEQMKQDRITRYQGVN--LYVKNLDDGIDDERLRKEFSPFGTITSAKVMMEGGRSKGF 335
+ +D + + N +Y + G+ D+ +R+ FSPFG I +V E KG+
Sbjct: 187 NTKQLRFEDVVNQSSPKNCTVYCGGIASGLTDQLMRQTFSPFGQIMEIRVFPE----KGY 242
Query: 336 GFVCFSSPEEATKAVTEMNGRIV 358
FV FS+ E A A+ +NG +
Sbjct: 243 SFVRFSTHESAAHAIVSVNGTTI 265
Score = 112 bits (280), Expect = 1e-24
Identities = 84/268 (31%), Positives = 123/268 (45%), Gaps = 31/268 (11%)
Query: 12 SLYVGDLHPDVTEAMLYEKFSPAGPILSIRVCRDMITRRSLG--YAYVNFQQPADAERAL 69
+LYVG+L DVTE ++ + FS GP S + MIT + Y +V F + DA AL
Sbjct: 10 TLYVGNLSRDVTEVLILQLFSQIGPCKSCK----MITEHTSNDPYCFVEFYEHRDAAAAL 65
Query: 70 DTMNFDVIKGKPVRIMWSQRDPSLRKSGVGN---IFIKNLDKSIDNKALYDTFSAFGNIL 126
MN I GK V++ W+ PS +K N +F+ +L I + + F+ FG I
Sbjct: 66 AAMNGRKILGKEVKVNWA-TTPSSQKKDTSNHFHVFVGDLSPEITTEDIKSAFAPFGKIS 124
Query: 127 SCKVVCD--ENGSKGYGFVHFETQEAAERAIEKMNGMLLNDRKVFVG-------RFKSRK 177
+VV D SKGYGFV F + AE AI M G L R++ KS +
Sbjct: 125 DARVVKDMATGKSKGYGFVSFYNKLDAENAIVHMGGQWLGGRQIRTNWATRKPPAPKSTQ 184
Query: 178 ER-------EAELGARAKEFTNVYIKNFGEDMDDERLKDLFGKFGPALSVKVMTDESGKS 230
E E + + + VY + D+ ++ F FG + ++V +
Sbjct: 185 ENNTKQLRFEDVVNQSSPKNCTVYCGGIASGLTDQLMRQTFSPFGQIMEIRVFPE----- 239
Query: 231 KGFGFVSFERHEDAQKAVDEMNGKELNG 258
KG+ FV F HE A A+ +NG + G
Sbjct: 240 KGYSFVRFSTHESAAHAIVSVNGTTIEG 267
Score = 89.0 bits (219), Expect = 1e-17
Identities = 54/176 (30%), Positives = 82/176 (46%), Gaps = 24/176 (13%)
Query: 13 LYVGDLHPDVTEAMLYEKFSPAGPILSIRVCRDMITRRSLGYAYVNFQQPADAERALDTM 72
++VGDL P++T + F+P G I RV +DM T +S GY +V+F DAE A+ M
Sbjct: 99 VFVGDLSPEITTEDIKSAFAPFGKISDARVVKDMATGKSKGYGFVSFYNKLDAENAIVHM 158
Query: 73 NFDVIKGKPVRIMWSQRDPSLRKSGVGN--------------------IFIKNLDKSIDN 112
+ G+ +R W+ R P KS N ++ + + +
Sbjct: 159 GGQWLGGRQIRTNWATRKPPAPKSTQENNTKQLRFEDVVNQSSPKNCTVYCGGIASGLTD 218
Query: 113 KALYDTFSAFGNILSCKVVCDENGSKGYGFVHFETQEAAERAIEKMNGMLLNDRKV 168
+ + TFS FG I+ +V + KGY FV F T E+A AI +NG + V
Sbjct: 219 QLMRQTFSPFGQIMEIRVFPE----KGYSFVRFSTHESAAHAIVSVNGTTIEGHVV 270
Score = 86.3 bits (212), Expect = 8e-17
Identities = 52/181 (28%), Positives = 91/181 (50%), Gaps = 17/181 (9%)
Query: 193 VYIKNFGEDMDDERLKDLFGKFGPALSVKVMTDESGKSKGFGFVSFERHEDAQKAVDEMN 252
+Y+ N D+ + + LF + GP S K++T+ + + FV F H DA A+ MN
Sbjct: 11 LYVGNLSRDVTEVLILQLFSQIGPCKSCKMITEHTSNDP-YCFVEFYEHRDAAAALAAMN 69
Query: 253 GKELNGKQIYVGRAQKKVERQTELKRKFEQMKQDRITRYQGVNLYVKNLDDGIDDERLRK 312
G+++ GK++ V A ++ + F +++V +L I E ++
Sbjct: 70 GRKILGKEVKVNWATTPSSQKKDTSNHF--------------HVFVGDLSPEITTEDIKS 115
Query: 313 EFSPFGTITSAKVM--MEGGRSKGFGFVCFSSPEEATKAVTEMNGRIVATKPLYVALAQR 370
F+PFG I+ A+V+ M G+SKG+GFV F + +A A+ M G+ + + + A R
Sbjct: 116 AFAPFGKISDARVVKDMATGKSKGYGFVSFYNKLDAENAIVHMGGQWLGGRQIRTNWATR 175
Query: 371 K 371
K
Sbjct: 176 K 176
Score = 48.5 bits (114), Expect = 2e-05
Identities = 27/96 (28%), Positives = 49/96 (51%), Gaps = 8/96 (8%)
Query: 1 MNPSAPSYPMASLYVGDLHPDVTEAMLYEKFSPAGPILSIRVCRDMITRRSLGYAYVNFQ 60
+N S+P ++Y G + +T+ ++ + FSP G I+ IRV + GY++V F
Sbjct: 197 VNQSSPKN--CTVYCGGIASGLTDQLMRQTFSPFGQIMEIRVFPEK------GYSFVRFS 248
Query: 61 QPADAERALDTMNFDVIKGKPVRIMWSQRDPSLRKS 96
A A+ ++N I+G V+ W + P + K+
Sbjct: 249 THESAAHAIVSVNGTTIEGHVVKCYWGKESPDMTKN 284
>gi|115511032 ELAV (embryonic lethal, abnormal vision,
Drosophila)-like 2 (Hu antigen B) [Homo sapiens]
Length = 359
Score = 111 bits (278), Expect = 2e-24
Identities = 84/329 (25%), Positives = 152/329 (46%), Gaps = 64/329 (19%)
Query: 100 NIFIKNLDKSIDNKALYDTFSAFGNILSCKVVCDE--NGSKGYGFVHFETQEAAERAIEK 157
N+ + L +++ + L F + G I SCK+V D+ S GYGFV++ + AE+AI
Sbjct: 40 NLIVNYLPQNMTQEELKSLFGSIGEIESCKLVRDKITGQSLGYGFVNYIDPKDAEKAINT 99
Query: 158 MNGMLLNDR--KVFVGRFKSRKEREAELGARAKEFTNVYIKNFGEDMDDERLKDLFGKFG 215
+NG+ L + KV R S R+A N+Y+ + M + L+ LF ++G
Sbjct: 100 LNGLRLQTKTIKVSYARPSSASIRDA----------NLYVSGLPKTMTQKELEQLFSQYG 149
Query: 216 PALSVKVMTDE-SGKSKGFGFVSFERHEDAQKAVDEMNGKELNG---------------- 258
++ +++ D+ +G S+G GF+ F++ +A++A+ +NG++ G
Sbjct: 150 RIITSRILVDQVTGISRGVGFIRFDKRIEAEEAIKGLNGQKPPGATEPITVKFANNPSQK 209
Query: 259 -------------KQIYVGRAQKKVER--------QTELKRKFEQMKQDRITRYQGVN-- 295
+ Y G ++ +R ++F M D +T G+N
Sbjct: 210 TNQAILSQLYQSPNRRYPGPLAQQAQRFRLDNLLNMAYGVKRFSPMTIDGMTSLAGINIP 269
Query: 296 --------LYVKNLDDGIDDERLRKEFSPFGTITSAKVMME--GGRSKGFGFVCFSSPEE 345
++V NL D+ L + F PFG +T+ KV+ + + KGFGFV ++ +E
Sbjct: 270 GHPGTGWCIFVYNLAPDADESILWQMFGPFGAVTNVKVIRDFNTNKCKGFGFVTMTNYDE 329
Query: 346 ATKAVTEMNGRIVATKPLYVALAQRKEER 374
A A+ +NG + + L V+ K +
Sbjct: 330 AAMAIASLNGYRLGDRVLQVSFKTNKTHK 358
Score = 90.9 bits (224), Expect = 3e-18
Identities = 50/151 (33%), Positives = 89/151 (58%), Gaps = 4/151 (2%)
Query: 12 SLYVGDLHPDVTEAMLYEKFSPAGPILSIRVCRDMITRRSLGYAYVNFQQPADAERALDT 71
+L V L ++T+ L F G I S ++ RD IT +SLGY +VN+ P DAE+A++T
Sbjct: 40 NLIVNYLPQNMTQEELKSLFGSIGEIESCKLVRDKITGQSLGYGFVNYIDPKDAEKAINT 99
Query: 72 MNFDVIKGKPVRIMWSQRDPSLRKSGVGNIFIKNLDKSIDNKALYDTFSAFGNILSCKVV 131
+N ++ K +++ +++ PS N+++ L K++ K L FS +G I++ +++
Sbjct: 100 LNGLRLQTKTIKVSYAR--PSSASIRDANLYVSGLPKTMTQKELEQLFSQYGRIITSRIL 157
Query: 132 CDE--NGSKGYGFVHFETQEAAERAIEKMNG 160
D+ S+G GF+ F+ + AE AI+ +NG
Sbjct: 158 VDQVTGISRGVGFIRFDKRIEAEEAIKGLNG 188
Score = 86.3 bits (212), Expect = 8e-17
Identities = 64/218 (29%), Positives = 107/218 (49%), Gaps = 28/218 (12%)
Query: 191 TNVYIKNFGEDMDDERLKDLFGKFGPALSVKVMTDE-SGKSKGFGFVSFERHEDAQKAVD 249
TN+ + ++M E LK LFG G S K++ D+ +G+S G+GFV++ +DA+KA++
Sbjct: 39 TNLIVNYLPQNMTQEELKSLFGSIGEIESCKLVRDKITGQSLGYGFVNYIDPKDAEKAIN 98
Query: 250 EMNGKELNGKQIYVGRAQKKVERQTELKRKFEQMKQDRITRYQGVNLYVKNLDDGIDDER 309
+NG L K I V A+ + NLYV L + +
Sbjct: 99 TLNGLRLQTKTIKVSYARPS------------------SASIRDANLYVSGLPKTMTQKE 140
Query: 310 LRKEFSPFGTITSAKVMME--GGRSKGFGFVCFSSPEEATKAVTEMNGRIV--ATKPLYV 365
L + FS +G I +++++++ G S+G GF+ F EA +A+ +NG+ AT+P+ V
Sbjct: 141 LEQLFSQYGRIITSRILVDQVTGISRGVGFIRFDKRIEAEEAIKGLNGQKPPGATEPITV 200
Query: 366 ALAQRKEER--QAHLTNQYMQRMASVRAVPNPVINPYQ 401
A ++ QA L+ Y + R P P+ Q
Sbjct: 201 KFANNPSQKTNQAILSQLY---QSPNRRYPGPLAQQAQ 235
Score = 50.4 bits (119), Expect = 5e-06
Identities = 31/83 (37%), Positives = 42/83 (50%), Gaps = 3/83 (3%)
Query: 101 IFIKNLDKSIDNKALYDTFSAFGNILSCKVVCD--ENGSKGYGFVHFETQEAAERAIEKM 158
IF+ NL D L+ F FG + + KV+ D N KG+GFV + A AI +
Sbjct: 278 IFVYNLAPDADESILWQMFGPFGAVTNVKVIRDFNTNKCKGFGFVTMTNYDEAAMAIASL 337
Query: 159 NGMLLNDRKVFVGRFKSRKEREA 181
NG L DR + V FK+ K +A
Sbjct: 338 NGYRLGDRVLQVS-FKTNKTHKA 359
Score = 44.3 bits (103), Expect = 3e-04
Identities = 24/71 (33%), Positives = 39/71 (54%)
Query: 3 PSAPSYPMASLYVGDLHPDVTEAMLYEKFSPAGPILSIRVCRDMITRRSLGYAYVNFQQP 62
PS+ S A+LYV L +T+ L + FS G I++ R+ D +T S G ++ F +
Sbjct: 117 PSSASIRDANLYVSGLPKTMTQKELEQLFSQYGRIITSRILVDQVTGISRGVGFIRFDKR 176
Query: 63 ADAERALDTMN 73
+AE A+ +N
Sbjct: 177 IEAEEAIKGLN 187
Score = 43.5 bits (101), Expect = 6e-04
Identities = 18/61 (29%), Positives = 36/61 (59%)
Query: 13 LYVGDLHPDVTEAMLYEKFSPAGPILSIRVCRDMITRRSLGYAYVNFQQPADAERALDTM 72
++V +L PD E++L++ F P G + +++V RD T + G+ +V +A A+ ++
Sbjct: 278 IFVYNLAPDADESILWQMFGPFGAVTNVKVIRDFNTNKCKGFGFVTMTNYDEAAMAIASL 337
Query: 73 N 73
N
Sbjct: 338 N 338
>gi|49355761 ELAV-like protein 3 isoform 1 [Homo sapiens]
Length = 367
Score = 110 bits (274), Expect = 5e-24
Identities = 91/378 (24%), Positives = 166/378 (43%), Gaps = 66/378 (17%)
Query: 12 SLYVGDLHPDVTEAMLYEKFSPAGPILSIRVCRDMITRRSLGYAYVNFQQPADAERALDT 71
+L V L ++T+ F G I S ++ RD IT +SLGY +VN+ P DA++A++T
Sbjct: 40 NLIVNYLPQNMTQDEFKSLFGSIGDIESCKLVRDKITGQSLGYGFVNYSDPNDADKAINT 99
Query: 72 MNFDVIKGKPVRIMWSQRDPSLRKSGVGNIFIKNLDKSIDNKALYDTFSAFGNILSCKVV 131
+N ++ K +++ +++ PS N+++ L K++ K + FS +G I++ +++
Sbjct: 100 LNGLKLQTKTIKVSYAR--PSSASIRDANLYVSGLPKTMSQKEMEQLFSQYGRIITSRIL 157
Query: 132 CDE--NGSKGYGFVHFETQEAAERAIEKMNGMLLNDRKVFVGRFKSRKEREAELGARAKE 189
D+ S+G GF+ F+ + AE AI+ +NG + LGA A+
Sbjct: 158 VDQVTGVSRGVGFIRFDKRIEAEEAIKGLNG-------------------QKPLGA-AEP 197
Query: 190 FTNVYIKNFGEDMDDERLKDLFGKFGPALSVKVMTDESGKSKGFGFVSFERHEDAQKAVD 249
T + N + L L+ +S + H+ + +D
Sbjct: 198 ITVKFANNPSQKTGQALLTHLY-----------------QSSARRYAGPLHHQTQRFRLD 240
Query: 250 EMNGKELNGKQIYVGRAQKKVERQTELKRKFEQMKQDRITRYQGVNL-----------YV 298
+ V+ L +F + D ++ GV L +V
Sbjct: 241 NLLNMAYG------------VKSPLSLIARFSPIAIDGMSGLAGVGLSGGAAGAGWCIFV 288
Query: 299 KNLDDGIDDERLRKEFSPFGTITSAKVMME--GGRSKGFGFVCFSSPEEATKAVTEMNGR 356
NL D+ L + F PFG +T+ KV+ + + KGFGFV ++ +EA A+ +NG
Sbjct: 289 YNLSPEADESVLWQLFGPFGAVTNVKVIRDFTTNKCKGFGFVTMTNYDEAAMAIASLNGY 348
Query: 357 IVATKPLYVALAQRKEER 374
+ + L V+ K+ +
Sbjct: 349 RLGERVLQVSFKTSKQHK 366
Score = 85.9 bits (211), Expect = 1e-16
Identities = 62/220 (28%), Positives = 107/220 (48%), Gaps = 28/220 (12%)
Query: 184 GARAKEFTNVYIKNFGEDMDDERLKDLFGKFGPALSVKVMTDE-SGKSKGFGFVSFERHE 242
GA TN+ + ++M + K LFG G S K++ D+ +G+S G+GFV++
Sbjct: 32 GATDDSKTNLIVNYLPQNMTQDEFKSLFGSIGDIESCKLVRDKITGQSLGYGFVNYSDPN 91
Query: 243 DAQKAVDEMNGKELNGKQIYVGRAQKKVERQTELKRKFEQMKQDRITRYQGVNLYVKNLD 302
DA KA++ +NG +L K I V A+ + NLYV L
Sbjct: 92 DADKAINTLNGLKLQTKTIKVSYARPS------------------SASIRDANLYVSGLP 133
Query: 303 DGIDDERLRKEFSPFGTITSAKVMME--GGRSKGFGFVCFSSPEEATKAVTEMNGR--IV 358
+ + + + FS +G I +++++++ G S+G GF+ F EA +A+ +NG+ +
Sbjct: 134 KTMSQKEMEQLFSQYGRIITSRILVDQVTGVSRGVGFIRFDKRIEAEEAIKGLNGQKPLG 193
Query: 359 ATKPLYVALAQRKEER--QAHLTNQYMQRMASVRAVPNPV 396
A +P+ V A ++ QA LT+ Y +S R P+
Sbjct: 194 AAEPITVKFANNPSQKTGQALLTHLY---QSSARRYAGPL 230
Score = 64.7 bits (156), Expect = 2e-10
Identities = 62/264 (23%), Positives = 119/264 (45%), Gaps = 26/264 (9%)
Query: 3 PSAPSYPMASLYVGDLHPDVTEAMLYEKFSPAGPILSIRVCRDMITRRSLGYAYVNFQQP 62
PS+ S A+LYV L +++ + + FS G I++ R+ D +T S G ++ F +
Sbjct: 117 PSSASIRDANLYVSGLPKTMSQKEMEQLFSQYGRIITSRILVDQVTGVSRGVGFIRFDKR 176
Query: 63 ADAERALDTMNFDVIKG--KPVRIMWSQRDPSLRKSGVGNIFIKNLDKSIDNKALYDTFS 120
+AE A+ +N G +P+ + ++ +PS + G + +L +S + ++
Sbjct: 177 IEAEEAIKGLNGQKPLGAAEPITVKFA-NNPSQK---TGQALLTHLYQSSARR-----YA 227
Query: 121 AFGNILSCKVVCDENGSKGYGFVHFETQEAAERAIEKMNGMLLNDRKVFVGRFKSRKERE 180
+ + + D + YG ++ I + + + ++ G S
Sbjct: 228 GPLHHQTQRFRLDNLLNMAYGV------KSPLSLIARFSPIAIDGMSGLAGVGLS----- 276
Query: 181 AELGARAKEFTNVYIKNFGEDMDDERLKDLFGKFGPALSVKVMTD-ESGKSKGFGFVSFE 239
G A +++ N + D+ L LFG FG +VKV+ D + K KGFGFV+
Sbjct: 277 ---GGAAGAGWCIFVYNLSPEADESVLWQLFGPFGAVTNVKVIRDFTTNKCKGFGFVTMT 333
Query: 240 RHEDAQKAVDEMNGKELNGKQIYV 263
+++A A+ +NG L + + V
Sbjct: 334 NYDEAAMAIASLNGYRLGERVLQV 357
Score = 50.8 bits (120), Expect = 4e-06
Identities = 30/83 (36%), Positives = 43/83 (51%), Gaps = 3/83 (3%)
Query: 101 IFIKNLDKSIDNKALYDTFSAFGNILSCKVVCD--ENGSKGYGFVHFETQEAAERAIEKM 158
IF+ NL D L+ F FG + + KV+ D N KG+GFV + A AI +
Sbjct: 286 IFVYNLSPEADESVLWQLFGPFGAVTNVKVIRDFTTNKCKGFGFVTMTNYDEAAMAIASL 345
Query: 159 NGMLLNDRKVFVGRFKSRKEREA 181
NG L +R + V FK+ K+ +A
Sbjct: 346 NGYRLGERVLQVS-FKTSKQHKA 367
>gi|77695912 TIA-1 related protein isoform 2 [Homo sapiens]
Length = 392
Score = 108 bits (270), Expect = 2e-23
Identities = 82/281 (29%), Positives = 123/281 (43%), Gaps = 40/281 (14%)
Query: 12 SLYVGDLHPDVTEAMLYEKFSPAGPILSIRVCRDMITRRSLG---------------YAY 56
+LYVG+L DVTE ++ + FS GP S ++ + R + Y +
Sbjct: 10 TLYVGNLSRDVTEVLILQLFSQIGPCKSCKMITEQPDSRRVNSSVGFSVLQHTSNDPYCF 69
Query: 57 VNFQQPADAERALDTMNFDVIKGKPVRIMWSQRDPSLRKSGVGN---IFIKNLDKSIDNK 113
V F + DA AL MN I GK V++ W+ PS +K N +F+ +L I +
Sbjct: 70 VEFYEHRDAAAALAAMNGRKILGKEVKVNWA-TTPSSQKKDTSNHFHVFVGDLSPEITTE 128
Query: 114 ALYDTFSAFGNILSCKVVCD--ENGSKGYGFVHFETQEAAERAIEKMNGMLLNDRKVFVG 171
+ F+ FG I +VV D SKGYGFV F + AE AI M G L R++
Sbjct: 129 DIKSAFAPFGKISDARVVKDMATGKSKGYGFVSFYNKLDAENAIVHMGGQWLGGRQIRTN 188
Query: 172 -------RFKSRKER-------EAELGARAKEFTNVYIKNFGEDMDDERLKDLFGKFGPA 217
KS +E E + + + VY + D+ ++ F FG
Sbjct: 189 WATRKPPAPKSTQENNTKQLRFEDVVNQSSPKNCTVYCGGIASGLTDQLMRQTFSPFGQI 248
Query: 218 LSVKVMTDESGKSKGFGFVSFERHEDAQKAVDEMNGKELNG 258
+ ++V + KG+ FV F HE A A+ +NG + G
Sbjct: 249 MEIRVFPE-----KGYSFVRFSTHESAAHAIVSVNGTTIEG 284
Score = 107 bits (266), Expect = 4e-23
Identities = 77/280 (27%), Positives = 129/280 (46%), Gaps = 30/280 (10%)
Query: 101 IFIKNLDKSIDNKALYDTFSAFGNILSCKVVCDE------NGSKG-----------YGFV 143
+++ NL + + + FS G SCK++ ++ N S G Y FV
Sbjct: 11 LYVGNLSRDVTEVLILQLFSQIGPCKSCKMITEQPDSRRVNSSVGFSVLQHTSNDPYCFV 70
Query: 144 HFETQEAAERAIEKMNGMLLNDRKVFVGRFKSRKEREAELGARAKEFTNVYIKNFGEDMD 203
F A A+ MNG + ++V V + ++ + +V++ + ++
Sbjct: 71 EFYEHRDAAAALAAMNGRKILGKEVKVNWATTPSSQKKD----TSNHFHVFVGDLSPEIT 126
Query: 204 DERLKDLFGKFGPALSVKVMTD-ESGKSKGFGFVSFERHEDAQKAVDEMNGKELNGKQIY 262
E +K F FG +V+ D +GKSKG+GFVSF DA+ A+ M G+ L G+QI
Sbjct: 127 TEDIKSAFAPFGKISDARVVKDMATGKSKGYGFVSFYNKLDAENAIVHMGGQWLGGRQIR 186
Query: 263 VGRAQKK--VERQTELKRKFEQMKQDRITRYQGVN--LYVKNLDDGIDDERLRKEFSPFG 318
A +K + T+ + +D + + N +Y + G+ D+ +R+ FSPFG
Sbjct: 187 TNWATRKPPAPKSTQENNTKQLRFEDVVNQSSPKNCTVYCGGIASGLTDQLMRQTFSPFG 246
Query: 319 TITSAKVMMEGGRSKGFGFVCFSSPEEATKAVTEMNGRIV 358
I +V E KG+ FV FS+ E A A+ +NG +
Sbjct: 247 QIMEIRVFPE----KGYSFVRFSTHESAAHAIVSVNGTTI 282
Score = 89.0 bits (219), Expect = 1e-17
Identities = 54/176 (30%), Positives = 82/176 (46%), Gaps = 24/176 (13%)
Query: 13 LYVGDLHPDVTEAMLYEKFSPAGPILSIRVCRDMITRRSLGYAYVNFQQPADAERALDTM 72
++VGDL P++T + F+P G I RV +DM T +S GY +V+F DAE A+ M
Sbjct: 116 VFVGDLSPEITTEDIKSAFAPFGKISDARVVKDMATGKSKGYGFVSFYNKLDAENAIVHM 175
Query: 73 NFDVIKGKPVRIMWSQRDPSLRKSGVGN--------------------IFIKNLDKSIDN 112
+ G+ +R W+ R P KS N ++ + + +
Sbjct: 176 GGQWLGGRQIRTNWATRKPPAPKSTQENNTKQLRFEDVVNQSSPKNCTVYCGGIASGLTD 235
Query: 113 KALYDTFSAFGNILSCKVVCDENGSKGYGFVHFETQEAAERAIEKMNGMLLNDRKV 168
+ + TFS FG I+ +V + KGY FV F T E+A AI +NG + V
Sbjct: 236 QLMRQTFSPFGQIMEIRVFPE----KGYSFVRFSTHESAAHAIVSVNGTTIEGHVV 287
Score = 82.0 bits (201), Expect = 2e-15
Identities = 55/197 (27%), Positives = 93/197 (47%), Gaps = 32/197 (16%)
Query: 193 VYIKNFGEDMDDERLKDLFGKFGPALSVKVMTDES-----GKSKGFG-----------FV 236
+Y+ N D+ + + LF + GP S K++T++ S GF FV
Sbjct: 11 LYVGNLSRDVTEVLILQLFSQIGPCKSCKMITEQPDSRRVNSSVGFSVLQHTSNDPYCFV 70
Query: 237 SFERHEDAQKAVDEMNGKELNGKQIYVGRAQKKVERQTELKRKFEQMKQDRITRYQGVNL 296
F H DA A+ MNG+++ GK++ V A ++ + F ++
Sbjct: 71 EFYEHRDAAAALAAMNGRKILGKEVKVNWATTPSSQKKDTSNHF--------------HV 116
Query: 297 YVKNLDDGIDDERLRKEFSPFGTITSAKVM--MEGGRSKGFGFVCFSSPEEATKAVTEMN 354
+V +L I E ++ F+PFG I+ A+V+ M G+SKG+GFV F + +A A+ M
Sbjct: 117 FVGDLSPEITTEDIKSAFAPFGKISDARVVKDMATGKSKGYGFVSFYNKLDAENAIVHMG 176
Query: 355 GRIVATKPLYVALAQRK 371
G+ + + + A RK
Sbjct: 177 GQWLGGRQIRTNWATRK 193
Score = 48.5 bits (114), Expect = 2e-05
Identities = 27/96 (28%), Positives = 49/96 (51%), Gaps = 8/96 (8%)
Query: 1 MNPSAPSYPMASLYVGDLHPDVTEAMLYEKFSPAGPILSIRVCRDMITRRSLGYAYVNFQ 60
+N S+P ++Y G + +T+ ++ + FSP G I+ IRV + GY++V F
Sbjct: 214 VNQSSPKN--CTVYCGGIASGLTDQLMRQTFSPFGQIMEIRVFPEK------GYSFVRFS 265
Query: 61 QPADAERALDTMNFDVIKGKPVRIMWSQRDPSLRKS 96
A A+ ++N I+G V+ W + P + K+
Sbjct: 266 THESAAHAIVSVNGTTIEGHVVKCYWGKESPDMTKN 301
>gi|221316773 ELAV-like 4 isoform 5 [Homo sapiens]
Length = 369
Score = 107 bits (266), Expect = 4e-23
Identities = 81/329 (24%), Positives = 152/329 (46%), Gaps = 64/329 (19%)
Query: 100 NIFIKNLDKSIDNKALYDTFSAFGNILSCKVVCDE--NGSKGYGFVHFETQEAAERAIEK 157
N+ + L +++ + F + G I SCK+V D+ S GYGFV++ + AE+AI
Sbjct: 50 NLIVNYLPQNMTQEEFRSLFGSIGEIESCKLVRDKITGQSLGYGFVNYIDPKDAEKAINT 109
Query: 158 MNGMLLNDR--KVFVGRFKSRKEREAELGARAKEFTNVYIKNFGEDMDDERLKDLFGKFG 215
+NG+ L + KV R S R+A N+Y+ + M + L+ LF ++G
Sbjct: 110 LNGLRLQTKTIKVSYARPSSASIRDA----------NLYVSGLPKTMTQKELEQLFSQYG 159
Query: 216 PALSVKVMTDE-SGKSKGFGFVSFERHEDAQKAVDEMNGKELNG--KQIYVGRAQKKVER 272
++ +++ D+ +G S+G GF+ F++ +A++A+ +NG++ +G + I V A ++
Sbjct: 160 RIITSRILVDQVTGVSRGVGFIRFDKRIEAEEAIKGLNGQKPSGATEPITVKFANNPSQK 219
Query: 273 QTEL-----------------------------------KRKFEQMKQDRITRYQGVN-- 295
++ ++F + D +T G+N
Sbjct: 220 SSQALLSQLYQSPNRRYPGPLHHQAQRFRLDNLLNMAYGVKRFSPITIDGMTSLVGMNIP 279
Query: 296 --------LYVKNLDDGIDDERLRKEFSPFGTITSAKVMME--GGRSKGFGFVCFSSPEE 345
++V NL D+ L + F PFG + + KV+ + + KGFGFV ++ +E
Sbjct: 280 GHTGTGWCIFVYNLSPDSDESVLWQLFGPFGAVNNVKVIRDFNTNKCKGFGFVTMTNYDE 339
Query: 346 ATKAVTEMNGRIVATKPLYVALAQRKEER 374
A A+ +NG + + L V+ K +
Sbjct: 340 AAMAIASLNGYRLGDRVLQVSFKTNKAHK 368
Score = 89.7 bits (221), Expect = 7e-18
Identities = 49/151 (32%), Positives = 88/151 (58%), Gaps = 4/151 (2%)
Query: 12 SLYVGDLHPDVTEAMLYEKFSPAGPILSIRVCRDMITRRSLGYAYVNFQQPADAERALDT 71
+L V L ++T+ F G I S ++ RD IT +SLGY +VN+ P DAE+A++T
Sbjct: 50 NLIVNYLPQNMTQEEFRSLFGSIGEIESCKLVRDKITGQSLGYGFVNYIDPKDAEKAINT 109
Query: 72 MNFDVIKGKPVRIMWSQRDPSLRKSGVGNIFIKNLDKSIDNKALYDTFSAFGNILSCKVV 131
+N ++ K +++ +++ PS N+++ L K++ K L FS +G I++ +++
Sbjct: 110 LNGLRLQTKTIKVSYAR--PSSASIRDANLYVSGLPKTMTQKELEQLFSQYGRIITSRIL 167
Query: 132 CDE--NGSKGYGFVHFETQEAAERAIEKMNG 160
D+ S+G GF+ F+ + AE AI+ +NG
Sbjct: 168 VDQVTGVSRGVGFIRFDKRIEAEEAIKGLNG 198
Score = 83.2 bits (204), Expect = 7e-16
Identities = 61/213 (28%), Positives = 105/213 (49%), Gaps = 28/213 (13%)
Query: 191 TNVYIKNFGEDMDDERLKDLFGKFGPALSVKVMTDE-SGKSKGFGFVSFERHEDAQKAVD 249
TN+ + ++M E + LFG G S K++ D+ +G+S G+GFV++ +DA+KA++
Sbjct: 49 TNLIVNYLPQNMTQEEFRSLFGSIGEIESCKLVRDKITGQSLGYGFVNYIDPKDAEKAIN 108
Query: 250 EMNGKELNGKQIYVGRAQKKVERQTELKRKFEQMKQDRITRYQGVNLYVKNLDDGIDDER 309
+NG L K I V A+ + NLYV L + +
Sbjct: 109 TLNGLRLQTKTIKVSYARPS------------------SASIRDANLYVSGLPKTMTQKE 150
Query: 310 LRKEFSPFGTITSAKVMME--GGRSKGFGFVCFSSPEEATKAVTEMNGR--IVATKPLYV 365
L + FS +G I +++++++ G S+G GF+ F EA +A+ +NG+ AT+P+ V
Sbjct: 151 LEQLFSQYGRIITSRILVDQVTGVSRGVGFIRFDKRIEAEEAIKGLNGQKPSGATEPITV 210
Query: 366 ALAQRKEER--QAHLTNQYMQRMASVRAVPNPV 396
A ++ QA L+ Y + R P P+
Sbjct: 211 KFANNPSQKSSQALLSQLY---QSPNRRYPGPL 240
Score = 49.3 bits (116), Expect = 1e-05
Identities = 30/83 (36%), Positives = 42/83 (50%), Gaps = 3/83 (3%)
Query: 101 IFIKNLDKSIDNKALYDTFSAFGNILSCKVVCD--ENGSKGYGFVHFETQEAAERAIEKM 158
IF+ NL D L+ F FG + + KV+ D N KG+GFV + A AI +
Sbjct: 288 IFVYNLSPDSDESVLWQLFGPFGAVNNVKVIRDFNTNKCKGFGFVTMTNYDEAAMAIASL 347
Query: 159 NGMLLNDRKVFVGRFKSRKEREA 181
NG L DR + V FK+ K ++
Sbjct: 348 NGYRLGDRVLQVS-FKTNKAHKS 369
Score = 45.4 bits (106), Expect = 2e-04
Identities = 29/96 (30%), Positives = 51/96 (53%), Gaps = 3/96 (3%)
Query: 3 PSAPSYPMASLYVGDLHPDVTEAMLYEKFSPAGPILSIRVCRDMITRRSLGYAYVNFQQP 62
PS+ S A+LYV L +T+ L + FS G I++ R+ D +T S G ++ F +
Sbjct: 127 PSSASIRDANLYVSGLPKTMTQKELEQLFSQYGRIITSRILVDQVTGVSRGVGFIRFDKR 186
Query: 63 ADAERALDTMNFDVIKG--KPVRIMWSQRDPSLRKS 96
+AE A+ +N G +P+ + ++ +PS + S
Sbjct: 187 IEAEEAIKGLNGQKPSGATEPITVKFA-NNPSQKSS 221
Score = 42.0 bits (97), Expect = 0.002
Identities = 18/61 (29%), Positives = 36/61 (59%)
Query: 13 LYVGDLHPDVTEAMLYEKFSPAGPILSIRVCRDMITRRSLGYAYVNFQQPADAERALDTM 72
++V +L PD E++L++ F P G + +++V RD T + G+ +V +A A+ ++
Sbjct: 288 IFVYNLSPDSDESVLWQLFGPFGAVNNVKVIRDFNTNKCKGFGFVTMTNYDEAAMAIASL 347
Query: 73 N 73
N
Sbjct: 348 N 348
>gi|221316771 ELAV-like 4 isoform 4 [Homo sapiens]
Length = 366
Score = 107 bits (266), Expect = 4e-23
Identities = 81/329 (24%), Positives = 152/329 (46%), Gaps = 64/329 (19%)
Query: 100 NIFIKNLDKSIDNKALYDTFSAFGNILSCKVVCDE--NGSKGYGFVHFETQEAAERAIEK 157
N+ + L +++ + F + G I SCK+V D+ S GYGFV++ + AE+AI
Sbjct: 47 NLIVNYLPQNMTQEEFRSLFGSIGEIESCKLVRDKITGQSLGYGFVNYIDPKDAEKAINT 106
Query: 158 MNGMLLNDR--KVFVGRFKSRKEREAELGARAKEFTNVYIKNFGEDMDDERLKDLFGKFG 215
+NG+ L + KV R S R+A N+Y+ + M + L+ LF ++G
Sbjct: 107 LNGLRLQTKTIKVSYARPSSASIRDA----------NLYVSGLPKTMTQKELEQLFSQYG 156
Query: 216 PALSVKVMTDE-SGKSKGFGFVSFERHEDAQKAVDEMNGKELNG--KQIYVGRAQKKVER 272
++ +++ D+ +G S+G GF+ F++ +A++A+ +NG++ +G + I V A ++
Sbjct: 157 RIITSRILVDQVTGVSRGVGFIRFDKRIEAEEAIKGLNGQKPSGATEPITVKFANNPSQK 216
Query: 273 QTEL-----------------------------------KRKFEQMKQDRITRYQGVN-- 295
++ ++F + D +T G+N
Sbjct: 217 SSQALLSQLYQSPNRRYPGPLHHQAQRFRLDNLLNMAYGVKRFSPITIDGMTSLVGMNIP 276
Query: 296 --------LYVKNLDDGIDDERLRKEFSPFGTITSAKVMME--GGRSKGFGFVCFSSPEE 345
++V NL D+ L + F PFG + + KV+ + + KGFGFV ++ +E
Sbjct: 277 GHTGTGWCIFVYNLSPDSDESVLWQLFGPFGAVNNVKVIRDFNTNKCKGFGFVTMTNYDE 336
Query: 346 ATKAVTEMNGRIVATKPLYVALAQRKEER 374
A A+ +NG + + L V+ K +
Sbjct: 337 AAMAIASLNGYRLGDRVLQVSFKTNKAHK 365
Score = 89.7 bits (221), Expect = 7e-18
Identities = 49/151 (32%), Positives = 88/151 (58%), Gaps = 4/151 (2%)
Query: 12 SLYVGDLHPDVTEAMLYEKFSPAGPILSIRVCRDMITRRSLGYAYVNFQQPADAERALDT 71
+L V L ++T+ F G I S ++ RD IT +SLGY +VN+ P DAE+A++T
Sbjct: 47 NLIVNYLPQNMTQEEFRSLFGSIGEIESCKLVRDKITGQSLGYGFVNYIDPKDAEKAINT 106
Query: 72 MNFDVIKGKPVRIMWSQRDPSLRKSGVGNIFIKNLDKSIDNKALYDTFSAFGNILSCKVV 131
+N ++ K +++ +++ PS N+++ L K++ K L FS +G I++ +++
Sbjct: 107 LNGLRLQTKTIKVSYAR--PSSASIRDANLYVSGLPKTMTQKELEQLFSQYGRIITSRIL 164
Query: 132 CDE--NGSKGYGFVHFETQEAAERAIEKMNG 160
D+ S+G GF+ F+ + AE AI+ +NG
Sbjct: 165 VDQVTGVSRGVGFIRFDKRIEAEEAIKGLNG 195
Score = 83.2 bits (204), Expect = 7e-16
Identities = 61/213 (28%), Positives = 105/213 (49%), Gaps = 28/213 (13%)
Query: 191 TNVYIKNFGEDMDDERLKDLFGKFGPALSVKVMTDE-SGKSKGFGFVSFERHEDAQKAVD 249
TN+ + ++M E + LFG G S K++ D+ +G+S G+GFV++ +DA+KA++
Sbjct: 46 TNLIVNYLPQNMTQEEFRSLFGSIGEIESCKLVRDKITGQSLGYGFVNYIDPKDAEKAIN 105
Query: 250 EMNGKELNGKQIYVGRAQKKVERQTELKRKFEQMKQDRITRYQGVNLYVKNLDDGIDDER 309
+NG L K I V A+ + NLYV L + +
Sbjct: 106 TLNGLRLQTKTIKVSYARPS------------------SASIRDANLYVSGLPKTMTQKE 147
Query: 310 LRKEFSPFGTITSAKVMME--GGRSKGFGFVCFSSPEEATKAVTEMNGR--IVATKPLYV 365
L + FS +G I +++++++ G S+G GF+ F EA +A+ +NG+ AT+P+ V
Sbjct: 148 LEQLFSQYGRIITSRILVDQVTGVSRGVGFIRFDKRIEAEEAIKGLNGQKPSGATEPITV 207
Query: 366 ALAQRKEER--QAHLTNQYMQRMASVRAVPNPV 396
A ++ QA L+ Y + R P P+
Sbjct: 208 KFANNPSQKSSQALLSQLY---QSPNRRYPGPL 237
Score = 49.3 bits (116), Expect = 1e-05
Identities = 30/83 (36%), Positives = 42/83 (50%), Gaps = 3/83 (3%)
Query: 101 IFIKNLDKSIDNKALYDTFSAFGNILSCKVVCD--ENGSKGYGFVHFETQEAAERAIEKM 158
IF+ NL D L+ F FG + + KV+ D N KG+GFV + A AI +
Sbjct: 285 IFVYNLSPDSDESVLWQLFGPFGAVNNVKVIRDFNTNKCKGFGFVTMTNYDEAAMAIASL 344
Query: 159 NGMLLNDRKVFVGRFKSRKEREA 181
NG L DR + V FK+ K ++
Sbjct: 345 NGYRLGDRVLQVS-FKTNKAHKS 366
Score = 45.4 bits (106), Expect = 2e-04
Identities = 29/96 (30%), Positives = 51/96 (53%), Gaps = 3/96 (3%)
Query: 3 PSAPSYPMASLYVGDLHPDVTEAMLYEKFSPAGPILSIRVCRDMITRRSLGYAYVNFQQP 62
PS+ S A+LYV L +T+ L + FS G I++ R+ D +T S G ++ F +
Sbjct: 124 PSSASIRDANLYVSGLPKTMTQKELEQLFSQYGRIITSRILVDQVTGVSRGVGFIRFDKR 183
Query: 63 ADAERALDTMNFDVIKG--KPVRIMWSQRDPSLRKS 96
+AE A+ +N G +P+ + ++ +PS + S
Sbjct: 184 IEAEEAIKGLNGQKPSGATEPITVKFA-NNPSQKSS 218
Score = 42.0 bits (97), Expect = 0.002
Identities = 18/61 (29%), Positives = 36/61 (59%)
Query: 13 LYVGDLHPDVTEAMLYEKFSPAGPILSIRVCRDMITRRSLGYAYVNFQQPADAERALDTM 72
++V +L PD E++L++ F P G + +++V RD T + G+ +V +A A+ ++
Sbjct: 285 IFVYNLSPDSDESVLWQLFGPFGAVNNVKVIRDFNTNKCKGFGFVTMTNYDEAAMAIASL 344
Query: 73 N 73
N
Sbjct: 345 N 345
>gi|221316769 ELAV-like 4 isoform 3 [Homo sapiens]
Length = 383
Score = 107 bits (266), Expect = 4e-23
Identities = 81/329 (24%), Positives = 152/329 (46%), Gaps = 64/329 (19%)
Query: 100 NIFIKNLDKSIDNKALYDTFSAFGNILSCKVVCDE--NGSKGYGFVHFETQEAAERAIEK 157
N+ + L +++ + F + G I SCK+V D+ S GYGFV++ + AE+AI
Sbjct: 64 NLIVNYLPQNMTQEEFRSLFGSIGEIESCKLVRDKITGQSLGYGFVNYIDPKDAEKAINT 123
Query: 158 MNGMLLNDR--KVFVGRFKSRKEREAELGARAKEFTNVYIKNFGEDMDDERLKDLFGKFG 215
+NG+ L + KV R S R+A N+Y+ + M + L+ LF ++G
Sbjct: 124 LNGLRLQTKTIKVSYARPSSASIRDA----------NLYVSGLPKTMTQKELEQLFSQYG 173
Query: 216 PALSVKVMTDE-SGKSKGFGFVSFERHEDAQKAVDEMNGKELNG--KQIYVGRAQKKVER 272
++ +++ D+ +G S+G GF+ F++ +A++A+ +NG++ +G + I V A ++
Sbjct: 174 RIITSRILVDQVTGVSRGVGFIRFDKRIEAEEAIKGLNGQKPSGATEPITVKFANNPSQK 233
Query: 273 QTEL-----------------------------------KRKFEQMKQDRITRYQGVN-- 295
++ ++F + D +T G+N
Sbjct: 234 SSQALLSQLYQSPNRRYPGPLHHQAQRFRLDNLLNMAYGVKRFSPITIDGMTSLVGMNIP 293
Query: 296 --------LYVKNLDDGIDDERLRKEFSPFGTITSAKVMME--GGRSKGFGFVCFSSPEE 345
++V NL D+ L + F PFG + + KV+ + + KGFGFV ++ +E
Sbjct: 294 GHTGTGWCIFVYNLSPDSDESVLWQLFGPFGAVNNVKVIRDFNTNKCKGFGFVTMTNYDE 353
Query: 346 ATKAVTEMNGRIVATKPLYVALAQRKEER 374
A A+ +NG + + L V+ K +
Sbjct: 354 AAMAIASLNGYRLGDRVLQVSFKTNKAHK 382
Score = 89.7 bits (221), Expect = 7e-18
Identities = 49/151 (32%), Positives = 88/151 (58%), Gaps = 4/151 (2%)
Query: 12 SLYVGDLHPDVTEAMLYEKFSPAGPILSIRVCRDMITRRSLGYAYVNFQQPADAERALDT 71
+L V L ++T+ F G I S ++ RD IT +SLGY +VN+ P DAE+A++T
Sbjct: 64 NLIVNYLPQNMTQEEFRSLFGSIGEIESCKLVRDKITGQSLGYGFVNYIDPKDAEKAINT 123
Query: 72 MNFDVIKGKPVRIMWSQRDPSLRKSGVGNIFIKNLDKSIDNKALYDTFSAFGNILSCKVV 131
+N ++ K +++ +++ PS N+++ L K++ K L FS +G I++ +++
Sbjct: 124 LNGLRLQTKTIKVSYAR--PSSASIRDANLYVSGLPKTMTQKELEQLFSQYGRIITSRIL 181
Query: 132 CDE--NGSKGYGFVHFETQEAAERAIEKMNG 160
D+ S+G GF+ F+ + AE AI+ +NG
Sbjct: 182 VDQVTGVSRGVGFIRFDKRIEAEEAIKGLNG 212
Score = 83.2 bits (204), Expect = 7e-16
Identities = 61/213 (28%), Positives = 105/213 (49%), Gaps = 28/213 (13%)
Query: 191 TNVYIKNFGEDMDDERLKDLFGKFGPALSVKVMTDE-SGKSKGFGFVSFERHEDAQKAVD 249
TN+ + ++M E + LFG G S K++ D+ +G+S G+GFV++ +DA+KA++
Sbjct: 63 TNLIVNYLPQNMTQEEFRSLFGSIGEIESCKLVRDKITGQSLGYGFVNYIDPKDAEKAIN 122
Query: 250 EMNGKELNGKQIYVGRAQKKVERQTELKRKFEQMKQDRITRYQGVNLYVKNLDDGIDDER 309
+NG L K I V A+ + NLYV L + +
Sbjct: 123 TLNGLRLQTKTIKVSYARPS------------------SASIRDANLYVSGLPKTMTQKE 164
Query: 310 LRKEFSPFGTITSAKVMME--GGRSKGFGFVCFSSPEEATKAVTEMNGR--IVATKPLYV 365
L + FS +G I +++++++ G S+G GF+ F EA +A+ +NG+ AT+P+ V
Sbjct: 165 LEQLFSQYGRIITSRILVDQVTGVSRGVGFIRFDKRIEAEEAIKGLNGQKPSGATEPITV 224
Query: 366 ALAQRKEER--QAHLTNQYMQRMASVRAVPNPV 396
A ++ QA L+ Y + R P P+
Sbjct: 225 KFANNPSQKSSQALLSQLY---QSPNRRYPGPL 254
Score = 49.3 bits (116), Expect = 1e-05
Identities = 30/83 (36%), Positives = 42/83 (50%), Gaps = 3/83 (3%)
Query: 101 IFIKNLDKSIDNKALYDTFSAFGNILSCKVVCD--ENGSKGYGFVHFETQEAAERAIEKM 158
IF+ NL D L+ F FG + + KV+ D N KG+GFV + A AI +
Sbjct: 302 IFVYNLSPDSDESVLWQLFGPFGAVNNVKVIRDFNTNKCKGFGFVTMTNYDEAAMAIASL 361
Query: 159 NGMLLNDRKVFVGRFKSRKEREA 181
NG L DR + V FK+ K ++
Sbjct: 362 NGYRLGDRVLQVS-FKTNKAHKS 383
Score = 45.4 bits (106), Expect = 2e-04
Identities = 29/96 (30%), Positives = 51/96 (53%), Gaps = 3/96 (3%)
Query: 3 PSAPSYPMASLYVGDLHPDVTEAMLYEKFSPAGPILSIRVCRDMITRRSLGYAYVNFQQP 62
PS+ S A+LYV L +T+ L + FS G I++ R+ D +T S G ++ F +
Sbjct: 141 PSSASIRDANLYVSGLPKTMTQKELEQLFSQYGRIITSRILVDQVTGVSRGVGFIRFDKR 200
Query: 63 ADAERALDTMNFDVIKG--KPVRIMWSQRDPSLRKS 96
+AE A+ +N G +P+ + ++ +PS + S
Sbjct: 201 IEAEEAIKGLNGQKPSGATEPITVKFA-NNPSQKSS 235
Score = 42.0 bits (97), Expect = 0.002
Identities = 18/61 (29%), Positives = 36/61 (59%)
Query: 13 LYVGDLHPDVTEAMLYEKFSPAGPILSIRVCRDMITRRSLGYAYVNFQQPADAERALDTM 72
++V +L PD E++L++ F P G + +++V RD T + G+ +V +A A+ ++
Sbjct: 302 IFVYNLSPDSDESVLWQLFGPFGAVNNVKVIRDFNTNKCKGFGFVTMTNYDEAAMAIASL 361
Query: 73 N 73
N
Sbjct: 362 N 362
>gi|221316767 ELAV-like 4 isoform 2 [Homo sapiens]
Length = 366
Score = 107 bits (266), Expect = 4e-23
Identities = 81/329 (24%), Positives = 152/329 (46%), Gaps = 64/329 (19%)
Query: 100 NIFIKNLDKSIDNKALYDTFSAFGNILSCKVVCDE--NGSKGYGFVHFETQEAAERAIEK 157
N+ + L +++ + F + G I SCK+V D+ S GYGFV++ + AE+AI
Sbjct: 47 NLIVNYLPQNMTQEEFRSLFGSIGEIESCKLVRDKITGQSLGYGFVNYIDPKDAEKAINT 106
Query: 158 MNGMLLNDR--KVFVGRFKSRKEREAELGARAKEFTNVYIKNFGEDMDDERLKDLFGKFG 215
+NG+ L + KV R S R+A N+Y+ + M + L+ LF ++G
Sbjct: 107 LNGLRLQTKTIKVSYARPSSASIRDA----------NLYVSGLPKTMTQKELEQLFSQYG 156
Query: 216 PALSVKVMTDE-SGKSKGFGFVSFERHEDAQKAVDEMNGKELNG--KQIYVGRAQKKVER 272
++ +++ D+ +G S+G GF+ F++ +A++A+ +NG++ +G + I V A ++
Sbjct: 157 RIITSRILVDQVTGVSRGVGFIRFDKRIEAEEAIKGLNGQKPSGATEPITVKFANNPSQK 216
Query: 273 QTEL-----------------------------------KRKFEQMKQDRITRYQGVN-- 295
++ ++F + D +T G+N
Sbjct: 217 SSQALLSQLYQSPNRRYPGPLHHQAQRFRLDNLLNMAYGVKRFSPITIDGMTSLVGMNIP 276
Query: 296 --------LYVKNLDDGIDDERLRKEFSPFGTITSAKVMME--GGRSKGFGFVCFSSPEE 345
++V NL D+ L + F PFG + + KV+ + + KGFGFV ++ +E
Sbjct: 277 GHTGTGWCIFVYNLSPDSDESVLWQLFGPFGAVNNVKVIRDFNTNKCKGFGFVTMTNYDE 336
Query: 346 ATKAVTEMNGRIVATKPLYVALAQRKEER 374
A A+ +NG + + L V+ K +
Sbjct: 337 AAMAIASLNGYRLGDRVLQVSFKTNKAHK 365
Score = 89.7 bits (221), Expect = 7e-18
Identities = 49/151 (32%), Positives = 88/151 (58%), Gaps = 4/151 (2%)
Query: 12 SLYVGDLHPDVTEAMLYEKFSPAGPILSIRVCRDMITRRSLGYAYVNFQQPADAERALDT 71
+L V L ++T+ F G I S ++ RD IT +SLGY +VN+ P DAE+A++T
Sbjct: 47 NLIVNYLPQNMTQEEFRSLFGSIGEIESCKLVRDKITGQSLGYGFVNYIDPKDAEKAINT 106
Query: 72 MNFDVIKGKPVRIMWSQRDPSLRKSGVGNIFIKNLDKSIDNKALYDTFSAFGNILSCKVV 131
+N ++ K +++ +++ PS N+++ L K++ K L FS +G I++ +++
Sbjct: 107 LNGLRLQTKTIKVSYAR--PSSASIRDANLYVSGLPKTMTQKELEQLFSQYGRIITSRIL 164
Query: 132 CDE--NGSKGYGFVHFETQEAAERAIEKMNG 160
D+ S+G GF+ F+ + AE AI+ +NG
Sbjct: 165 VDQVTGVSRGVGFIRFDKRIEAEEAIKGLNG 195
Score = 83.2 bits (204), Expect = 7e-16
Identities = 61/213 (28%), Positives = 105/213 (49%), Gaps = 28/213 (13%)
Query: 191 TNVYIKNFGEDMDDERLKDLFGKFGPALSVKVMTDE-SGKSKGFGFVSFERHEDAQKAVD 249
TN+ + ++M E + LFG G S K++ D+ +G+S G+GFV++ +DA+KA++
Sbjct: 46 TNLIVNYLPQNMTQEEFRSLFGSIGEIESCKLVRDKITGQSLGYGFVNYIDPKDAEKAIN 105
Query: 250 EMNGKELNGKQIYVGRAQKKVERQTELKRKFEQMKQDRITRYQGVNLYVKNLDDGIDDER 309
+NG L K I V A+ + NLYV L + +
Sbjct: 106 TLNGLRLQTKTIKVSYARPS------------------SASIRDANLYVSGLPKTMTQKE 147
Query: 310 LRKEFSPFGTITSAKVMME--GGRSKGFGFVCFSSPEEATKAVTEMNGR--IVATKPLYV 365
L + FS +G I +++++++ G S+G GF+ F EA +A+ +NG+ AT+P+ V
Sbjct: 148 LEQLFSQYGRIITSRILVDQVTGVSRGVGFIRFDKRIEAEEAIKGLNGQKPSGATEPITV 207
Query: 366 ALAQRKEER--QAHLTNQYMQRMASVRAVPNPV 396
A ++ QA L+ Y + R P P+
Sbjct: 208 KFANNPSQKSSQALLSQLY---QSPNRRYPGPL 237
Score = 49.3 bits (116), Expect = 1e-05
Identities = 30/83 (36%), Positives = 42/83 (50%), Gaps = 3/83 (3%)
Query: 101 IFIKNLDKSIDNKALYDTFSAFGNILSCKVVCD--ENGSKGYGFVHFETQEAAERAIEKM 158
IF+ NL D L+ F FG + + KV+ D N KG+GFV + A AI +
Sbjct: 285 IFVYNLSPDSDESVLWQLFGPFGAVNNVKVIRDFNTNKCKGFGFVTMTNYDEAAMAIASL 344
Query: 159 NGMLLNDRKVFVGRFKSRKEREA 181
NG L DR + V FK+ K ++
Sbjct: 345 NGYRLGDRVLQVS-FKTNKAHKS 366
Score = 45.4 bits (106), Expect = 2e-04
Identities = 29/96 (30%), Positives = 51/96 (53%), Gaps = 3/96 (3%)
Query: 3 PSAPSYPMASLYVGDLHPDVTEAMLYEKFSPAGPILSIRVCRDMITRRSLGYAYVNFQQP 62
PS+ S A+LYV L +T+ L + FS G I++ R+ D +T S G ++ F +
Sbjct: 124 PSSASIRDANLYVSGLPKTMTQKELEQLFSQYGRIITSRILVDQVTGVSRGVGFIRFDKR 183
Query: 63 ADAERALDTMNFDVIKG--KPVRIMWSQRDPSLRKS 96
+AE A+ +N G +P+ + ++ +PS + S
Sbjct: 184 IEAEEAIKGLNGQKPSGATEPITVKFA-NNPSQKSS 218
Score = 42.0 bits (97), Expect = 0.002
Identities = 18/61 (29%), Positives = 36/61 (59%)
Query: 13 LYVGDLHPDVTEAMLYEKFSPAGPILSIRVCRDMITRRSLGYAYVNFQQPADAERALDTM 72
++V +L PD E++L++ F P G + +++V RD T + G+ +V +A A+ ++
Sbjct: 285 IFVYNLSPDSDESVLWQLFGPFGAVNNVKVIRDFNTNKCKGFGFVTMTNYDEAAMAIASL 344
Query: 73 N 73
N
Sbjct: 345 N 345
>gi|49355765 ELAV-like protein 3 isoform 2 [Homo sapiens]
Length = 360
Score = 106 bits (265), Expect = 6e-23
Identities = 82/330 (24%), Positives = 152/330 (46%), Gaps = 65/330 (19%)
Query: 100 NIFIKNLDKSIDNKALYDTFSAFGNILSCKVVCDE--NGSKGYGFVHFETQEAAERAIEK 157
N+ + L +++ F + G+I SCK+V D+ S GYGFV++ A++AI
Sbjct: 40 NLIVNYLPQNMTQDEFKSLFGSIGDIESCKLVRDKITGQSLGYGFVNYSDPNDADKAINT 99
Query: 158 MNGMLLNDR--KVFVGRFKSRKEREAELGARAKEFTNVYIKNFGEDMDDERLKDLFGKFG 215
+NG+ L + KV R S R+A N+Y+ + M + ++ LF ++G
Sbjct: 100 LNGLKLQTKTIKVSYARPSSASIRDA----------NLYVSGLPKTMSQKEMEQLFSQYG 149
Query: 216 PALSVKVMTDE-SGKSKGFGFVSFERHEDAQKAVDEMNGKELNG---------------- 258
++ +++ D+ +G S+G GF+ F++ +A++A+ +NG++ G
Sbjct: 150 RIITSRILVDQVTGVSRGVGFIRFDKRIEAEEAIKGLNGQKPLGAAEPITVKFANNPSQK 209
Query: 259 ------KQIYVGRAQK---KVERQTELKR------------KFEQMKQDRITRYQGVNL- 296
+Y A++ + QT+ R +F + D ++ GV L
Sbjct: 210 TGQALLTHLYQSSARRYAGPLHHQTQRFRLDNLLNMAYGVKRFSPIAIDGMSGLAGVGLS 269
Query: 297 ----------YVKNLDDGIDDERLRKEFSPFGTITSAKVMME--GGRSKGFGFVCFSSPE 344
+V NL D+ L + F PFG +T+ KV+ + + KGFGFV ++ +
Sbjct: 270 GGAAGAGWCIFVYNLSPEADESVLWQLFGPFGAVTNVKVIRDFTTNKCKGFGFVTMTNYD 329
Query: 345 EATKAVTEMNGRIVATKPLYVALAQRKEER 374
EA A+ +NG + + L V+ K+ +
Sbjct: 330 EAAMAIASLNGYRLGERVLQVSFKTSKQHK 359
Score = 89.0 bits (219), Expect = 1e-17
Identities = 47/151 (31%), Positives = 88/151 (58%), Gaps = 4/151 (2%)
Query: 12 SLYVGDLHPDVTEAMLYEKFSPAGPILSIRVCRDMITRRSLGYAYVNFQQPADAERALDT 71
+L V L ++T+ F G I S ++ RD IT +SLGY +VN+ P DA++A++T
Sbjct: 40 NLIVNYLPQNMTQDEFKSLFGSIGDIESCKLVRDKITGQSLGYGFVNYSDPNDADKAINT 99
Query: 72 MNFDVIKGKPVRIMWSQRDPSLRKSGVGNIFIKNLDKSIDNKALYDTFSAFGNILSCKVV 131
+N ++ K +++ +++ PS N+++ L K++ K + FS +G I++ +++
Sbjct: 100 LNGLKLQTKTIKVSYAR--PSSASIRDANLYVSGLPKTMSQKEMEQLFSQYGRIITSRIL 157
Query: 132 CDE--NGSKGYGFVHFETQEAAERAIEKMNG 160
D+ S+G GF+ F+ + AE AI+ +NG
Sbjct: 158 VDQVTGVSRGVGFIRFDKRIEAEEAIKGLNG 188
Score = 85.9 bits (211), Expect = 1e-16
Identities = 62/220 (28%), Positives = 107/220 (48%), Gaps = 28/220 (12%)
Query: 184 GARAKEFTNVYIKNFGEDMDDERLKDLFGKFGPALSVKVMTDE-SGKSKGFGFVSFERHE 242
GA TN+ + ++M + K LFG G S K++ D+ +G+S G+GFV++
Sbjct: 32 GATDDSKTNLIVNYLPQNMTQDEFKSLFGSIGDIESCKLVRDKITGQSLGYGFVNYSDPN 91
Query: 243 DAQKAVDEMNGKELNGKQIYVGRAQKKVERQTELKRKFEQMKQDRITRYQGVNLYVKNLD 302
DA KA++ +NG +L K I V A+ + NLYV L
Sbjct: 92 DADKAINTLNGLKLQTKTIKVSYARPS------------------SASIRDANLYVSGLP 133
Query: 303 DGIDDERLRKEFSPFGTITSAKVMME--GGRSKGFGFVCFSSPEEATKAVTEMNGR--IV 358
+ + + + FS +G I +++++++ G S+G GF+ F EA +A+ +NG+ +
Sbjct: 134 KTMSQKEMEQLFSQYGRIITSRILVDQVTGVSRGVGFIRFDKRIEAEEAIKGLNGQKPLG 193
Query: 359 ATKPLYVALAQRKEER--QAHLTNQYMQRMASVRAVPNPV 396
A +P+ V A ++ QA LT+ Y +S R P+
Sbjct: 194 AAEPITVKFANNPSQKTGQALLTHLY---QSSARRYAGPL 230
Score = 67.8 bits (164), Expect = 3e-11
Identities = 66/264 (25%), Positives = 120/264 (45%), Gaps = 33/264 (12%)
Query: 3 PSAPSYPMASLYVGDLHPDVTEAMLYEKFSPAGPILSIRVCRDMITRRSLGYAYVNFQQP 62
PS+ S A+LYV L +++ + + FS G I++ R+ D +T S G ++ F +
Sbjct: 117 PSSASIRDANLYVSGLPKTMSQKEMEQLFSQYGRIITSRILVDQVTGVSRGVGFIRFDKR 176
Query: 63 ADAERALDTMNFDVIKG--KPVRIMWSQRDPSLRKSGVGNIFIKNLDKSIDNKALYDTFS 120
+AE A+ +N G +P+ + ++ +PS + G + +L +S + ++
Sbjct: 177 IEAEEAIKGLNGQKPLGAAEPITVKFA-NNPSQK---TGQALLTHLYQSSARR-----YA 227
Query: 121 AFGNILSCKVVCDENGSKGYGFVHFETQEAAERAIEKMNGMLLNDRKVFVGRFKSRKERE 180
+ + + D + YG F + AI+ M+G+ VG
Sbjct: 228 GPLHHQTQRFRLDNLLNMAYGVKRF-----SPIAIDGMSGL------AGVGL-------- 268
Query: 181 AELGARAKEFTNVYIKNFGEDMDDERLKDLFGKFGPALSVKVMTD-ESGKSKGFGFVSFE 239
G A +++ N + D+ L LFG FG +VKV+ D + K KGFGFV+
Sbjct: 269 --SGGAAGAGWCIFVYNLSPEADESVLWQLFGPFGAVTNVKVIRDFTTNKCKGFGFVTMT 326
Query: 240 RHEDAQKAVDEMNGKELNGKQIYV 263
+++A A+ +NG L + + V
Sbjct: 327 NYDEAAMAIASLNGYRLGERVLQV 350
Score = 50.8 bits (120), Expect = 4e-06
Identities = 30/83 (36%), Positives = 43/83 (51%), Gaps = 3/83 (3%)
Query: 101 IFIKNLDKSIDNKALYDTFSAFGNILSCKVVCD--ENGSKGYGFVHFETQEAAERAIEKM 158
IF+ NL D L+ F FG + + KV+ D N KG+GFV + A AI +
Sbjct: 279 IFVYNLSPEADESVLWQLFGPFGAVTNVKVIRDFTTNKCKGFGFVTMTNYDEAAMAIASL 338
Query: 159 NGMLLNDRKVFVGRFKSRKEREA 181
NG L +R + V FK+ K+ +A
Sbjct: 339 NGYRLGERVLQVS-FKTSKQHKA 360
>gi|55956788 nucleolin [Homo sapiens]
Length = 710
Score = 104 bits (259), Expect = 3e-22
Identities = 93/358 (25%), Positives = 168/358 (46%), Gaps = 34/358 (9%)
Query: 12 SLYVGDLHPDVTEAMLYEKFSP--AGPILSIRVCRDMITRRSLGYAYVNFQQPADAERAL 69
+L+VG+L+ + + L S A L++ R +TR+ + YV+F+ D E+AL
Sbjct: 308 NLFVGNLNFNKSAPELKTGISDVFAKNDLAVVDVRIGMTRK---FGYVDFESAEDLEKAL 364
Query: 70 DTMNFDVIKGKPVRIMWSQRDPSLRKSGVGNIFIKNLDKSIDNKALYDTFSAFGNILSCK 129
+ V G +++ + S ++ + KNL + L + F I +
Sbjct: 365 ELTGLKVF-GNEIKLEKPKGKDSKKERDARTLLAKNLPYKVTQDELKEVFEDAAEI---R 420
Query: 130 VVCDENGSKGYGFVHFETQEAAERAIEKMNGMLLNDRKVFVGRFKSRKEREAELGAR--- 186
+V + SKG ++ F+T+ AE+ E+ G ++ R + + + + + G +
Sbjct: 421 LVSKDGKSKGIAYIEFKTEADAEKTFEEKQGTEIDGRSISLYYTGEKGQNQDYRGGKNST 480
Query: 187 -AKEFTNVYIKNFGEDMDDERLKDLFGKFGPALSVKVMTDESGKSKGFGFVSFERHEDAQ 245
+ E + + N +E L+++F K A +KV +++GKSKG+ F+ F EDA+
Sbjct: 481 WSGESKTLVLSNLSYSATEETLQEVFEK---ATFIKVPQNQNGKSKGYAFIEFASFEDAK 537
Query: 246 KAVDEMNGKELNGKQIYVGRAQKKVERQTELKRKFEQMKQDRITRYQGVNLYVKNLDDGI 305
+A++ N +E+ G+ I R + + R + R L+VK L +
Sbjct: 538 EALNSCNKREIEGRAI---RLELQGPRGSPNARS-----------QPSKTLFVKGLSEDT 583
Query: 306 DDERLRKEFSPFGTITSAKVM-MEGGRSKGFGFVCFSSPEEATKAVTEM-NGRIVATK 361
+E L++ F G++ + V E G SKGFGFV F+S E+A A M +G I K
Sbjct: 584 TEETLKESFD--GSVRARIVTDRETGSSKGFGFVDFNSEEDAKAAKEAMEDGEIDGNK 639
Score = 89.0 bits (219), Expect = 1e-17
Identities = 79/275 (28%), Positives = 130/275 (47%), Gaps = 33/275 (12%)
Query: 12 SLYVGDLHPDVTEAMLYEKFSPAGPILSIRVCRDMITRRSLGYAYVNFQQPADAERALDT 71
+L +L VT+ L E F A I V +D +S G AY+ F+ ADAE+ +
Sbjct: 394 TLLAKNLPYKVTQDELKEVFEDAAEIRL--VSKD---GKSKGIAYIEFKTEADAEKTFEE 448
Query: 72 MNFDVIKGKPVRIMWS-QRDPSLRKSGVGN---------IFIKNLDKSIDNKALYDTFSA 121
I G+ + + ++ ++ + G N + + NL S + L + F
Sbjct: 449 KQGTEIDGRSISLYYTGEKGQNQDYRGGKNSTWSGESKTLVLSNLSYSATEETLQEVFEK 508
Query: 122 FGNILSCKVVCDENG-SKGYGFVHFETQEAAERAIEKMNGMLLNDRKVFVGRFKSRKERE 180
I KV ++NG SKGY F+ F + E A+ A+ N + R + R E +
Sbjct: 509 ATFI---KVPQNQNGKSKGYAFIEFASFEDAKEALNSCNKREIEGRAI-------RLELQ 558
Query: 181 AELG---ARAKEFTNVYIKNFGEDMDDERLKDLFGKFGPALSVKVMTD-ESGKSKGFGFV 236
G AR++ +++K ED +E LK+ F ++ +++TD E+G SKGFGFV
Sbjct: 559 GPRGSPNARSQPSKTLFVKGLSEDTTEETLKE---SFDGSVRARIVTDRETGSSKGFGFV 615
Query: 237 SFERHEDAQKAVDEMNGKELNGKQIYVGRAQKKVE 271
F EDA+ A + M E++G ++ + A+ K E
Sbjct: 616 DFNSEEDAKAAKEAMEDGEIDGNKVTLDWAKPKGE 650
Score = 74.3 bits (181), Expect = 3e-13
Identities = 60/232 (25%), Positives = 111/232 (47%), Gaps = 21/232 (9%)
Query: 137 SKGYGFVHFETQEAAERAIEKMNGMLLNDRKVFVGRFKSRKEREAELGARAKEFTNVYIK 196
++ +G+V FE+ E E+A+E L KVF K K + + + ++ + K
Sbjct: 346 TRKFGYVDFESAEDLEKALE------LTGLKVFGNEIKLEKPKGKD-SKKERDARTLLAK 398
Query: 197 NFGEDMDDERLKDLFGKFGPALSVKVMTDESGKSKGFGFVSFERHEDAQKAVDEMNGKEL 256
N + + LK++F A +++++ + GKSKG ++ F+ DA+K +E G E+
Sbjct: 399 NLPYKVTQDELKEVFED---AAEIRLVSKD-GKSKGIAYIEFKTEADAEKTFEEKQGTEI 454
Query: 257 NGKQIYVGRAQKKVERQTELKRKFEQMKQDRITRYQGVNLYVKNLDDGIDDERLRKEFSP 316
+G+ I + +K + Q K + T L + NL +E L++ F
Sbjct: 455 DGRSISLYYTGEKGQNQDYRGGKNSTWSGESKT------LVLSNLSYSATEETLQEVFEK 508
Query: 317 FGTITSAKVMM-EGGRSKGFGFVCFSSPEEATKAVTEMNGRIVATKPLYVAL 367
T KV + G+SKG+ F+ F+S E+A +A+ N R + + + + L
Sbjct: 509 ---ATFIKVPQNQNGKSKGYAFIEFASFEDAKEALNSCNKREIEGRAIRLEL 557
Score = 51.2 bits (121), Expect = 3e-06
Identities = 53/232 (22%), Positives = 99/232 (42%), Gaps = 26/232 (11%)
Query: 146 ETQEAAERAIEKMNGMLLNDRKVFVGRFKSRKEREAEL--GARAKEFTNVYIKNFGEDMD 203
E +E E +++ G RK + + K+ E + + G N+++ N +
Sbjct: 264 EEEEEEEEPVKEAPGK----RKKEMAKQKAAPEAKKQKVEGTEPTTAFNLFVGNLNFNKS 319
Query: 204 DERLKDLFGKFGPALSVKVMTDESGKSKGFGFVSFERHEDAQKAVDEMNGKELNGKQIYV 263
LK + V+ G ++ FG+V FE ED +KA+ E+ G ++ G +I
Sbjct: 320 APELKTGISDVFAKNDLAVVDVRIGMTRKFGYVDFESAEDLEKAL-ELTGLKVFGNEI-- 376
Query: 264 GRAQKKVERQTELKRKFEQMKQDRITRYQGVNLYVKNLDDGIDDERLRKEFSPFGTITSA 323
K+E K K + K++R R L KNL + + L++ F I
Sbjct: 377 -----KLE-----KPKGKDSKKERDAR----TLLAKNLPYKVTQDELKEVFEDAAEI--- 419
Query: 324 KVMMEGGRSKGFGFVCFSSPEEATKAVTEMNGRIVATKPLYVALAQRKEERQ 375
+++ + G+SKG ++ F + +A K E G + + + + K + Q
Sbjct: 420 RLVSKDGKSKGIAYIEFKTEADAEKTFEEKQGTEIDGRSISLYYTGEKGQNQ 471
Score = 47.0 bits (110), Expect = 5e-05
Identities = 28/87 (32%), Positives = 43/87 (49%), Gaps = 3/87 (3%)
Query: 2 NPSAPSYPMASLYVGDLHPDVTEAMLYEKFSPAGPILSIRVCRDMITRRSLGYAYVNFQQ 61
+P+A S P +L+V L D TE L E F + + R+ D T S G+ +V+F
Sbjct: 563 SPNARSQPSKTLFVKGLSEDTTEETLKESFDGS---VRARIVTDRETGSSKGFGFVDFNS 619
Query: 62 PADAERALDTMNFDVIKGKPVRIMWSQ 88
DA+ A + M I G V + W++
Sbjct: 620 EEDAKAAKEAMEDGEIDGNKVTLDWAK 646
Score = 30.4 bits (67), Expect = 5.2
Identities = 45/175 (25%), Positives = 65/175 (37%), Gaps = 27/175 (15%)
Query: 184 GARAKEFTNVYIKNFGEDMDDERLKDLFGKFGPALSVKVMTDESGKSKGFGFVSFERHED 243
G +A + V KN ED D+E + DE + E E+
Sbjct: 218 GKKAAKVVPVKAKNVAEDEDEEEDDE---------DEDDDDDEDDEDDDDEDDEEEEEEE 268
Query: 244 AQKAVDEMNGKELN--GKQIYVGRAQKKVERQTELKRKFEQMKQDRITRYQGVNLYVKNL 301
++ V E GK KQ A+K+ TE F NL+V NL
Sbjct: 269 EEEPVKEAPGKRKKEMAKQKAAPEAKKQKVEGTEPTTAF--------------NLFVGNL 314
Query: 302 DDGIDDERLRKEFSP-FGTITSAKVMMEGGRSKGFGFVCFSSPEEATKAVTEMNG 355
+ L+ S F A V + G ++ FG+V F S E+ KA+ E+ G
Sbjct: 315 NFNKSAPELKTGISDVFAKNDLAVVDVRIGMTRKFGYVDFESAEDLEKAL-ELTG 368
>gi|221316765 ELAV-like 4 isoform 1 [Homo sapiens]
Length = 380
Score = 102 bits (253), Expect = 1e-21
Identities = 83/343 (24%), Positives = 151/343 (44%), Gaps = 78/343 (22%)
Query: 100 NIFIKNLDKSIDNKALYDTFSAFGNILSCKVVCDE--NGSKGYGFVHFETQEAAERAIEK 157
N+ + L +++ + F + G I SCK+V D+ S GYGFV++ + AE+AI
Sbjct: 47 NLIVNYLPQNMTQEEFRSLFGSIGEIESCKLVRDKITGQSLGYGFVNYIDPKDAEKAINT 106
Query: 158 MNGMLLNDR--KVFVGRFKSRKEREAELGARAKEFTNVYIKNFGEDMDDERLKDLFGKFG 215
+NG+ L + KV R S R+A N+Y+ + M + L+ LF ++G
Sbjct: 107 LNGLRLQTKTIKVSYARPSSASIRDA----------NLYVSGLPKTMTQKELEQLFSQYG 156
Query: 216 PALSVKVMTDE-SGKSKGFGFVSFERHEDAQKAVDEMNGKELNG---------------- 258
++ +++ D+ +G S+G GF+ F++ +A++A+ +NG++ +G
Sbjct: 157 RIITSRILVDQVTGVSRGVGFIRFDKRIEAEEAIKGLNGQKPSGATEPITVKFANNPSQK 216
Query: 259 ------KQIYVG----------------RAQKKVERQTELKR-------------KFEQM 283
Q+Y R + +KR +F +
Sbjct: 217 SSQALLSQLYQSPNRRYPGPLHHQAQRFRLDNLLNMAYGVKRLMSGPVPPSACPPRFSPI 276
Query: 284 KQDRITRYQGVN----------LYVKNLDDGIDDERLRKEFSPFGTITSAKVMME--GGR 331
D +T G+N ++V NL D+ L + F PFG + + KV+ + +
Sbjct: 277 TIDGMTSLVGMNIPGHTGTGWCIFVYNLSPDSDESVLWQLFGPFGAVNNVKVIRDFNTNK 336
Query: 332 SKGFGFVCFSSPEEATKAVTEMNGRIVATKPLYVALAQRKEER 374
KGFGFV ++ +EA A+ +NG + + L V+ K +
Sbjct: 337 CKGFGFVTMTNYDEAAMAIASLNGYRLGDRVLQVSFKTNKAHK 379
Score = 89.7 bits (221), Expect = 7e-18
Identities = 49/151 (32%), Positives = 88/151 (58%), Gaps = 4/151 (2%)
Query: 12 SLYVGDLHPDVTEAMLYEKFSPAGPILSIRVCRDMITRRSLGYAYVNFQQPADAERALDT 71
+L V L ++T+ F G I S ++ RD IT +SLGY +VN+ P DAE+A++T
Sbjct: 47 NLIVNYLPQNMTQEEFRSLFGSIGEIESCKLVRDKITGQSLGYGFVNYIDPKDAEKAINT 106
Query: 72 MNFDVIKGKPVRIMWSQRDPSLRKSGVGNIFIKNLDKSIDNKALYDTFSAFGNILSCKVV 131
+N ++ K +++ +++ PS N+++ L K++ K L FS +G I++ +++
Sbjct: 107 LNGLRLQTKTIKVSYAR--PSSASIRDANLYVSGLPKTMTQKELEQLFSQYGRIITSRIL 164
Query: 132 CDE--NGSKGYGFVHFETQEAAERAIEKMNG 160
D+ S+G GF+ F+ + AE AI+ +NG
Sbjct: 165 VDQVTGVSRGVGFIRFDKRIEAEEAIKGLNG 195
Score = 83.2 bits (204), Expect = 7e-16
Identities = 61/213 (28%), Positives = 105/213 (49%), Gaps = 28/213 (13%)
Query: 191 TNVYIKNFGEDMDDERLKDLFGKFGPALSVKVMTDE-SGKSKGFGFVSFERHEDAQKAVD 249
TN+ + ++M E + LFG G S K++ D+ +G+S G+GFV++ +DA+KA++
Sbjct: 46 TNLIVNYLPQNMTQEEFRSLFGSIGEIESCKLVRDKITGQSLGYGFVNYIDPKDAEKAIN 105
Query: 250 EMNGKELNGKQIYVGRAQKKVERQTELKRKFEQMKQDRITRYQGVNLYVKNLDDGIDDER 309
+NG L K I V A+ + NLYV L + +
Sbjct: 106 TLNGLRLQTKTIKVSYARPS------------------SASIRDANLYVSGLPKTMTQKE 147
Query: 310 LRKEFSPFGTITSAKVMME--GGRSKGFGFVCFSSPEEATKAVTEMNGR--IVATKPLYV 365
L + FS +G I +++++++ G S+G GF+ F EA +A+ +NG+ AT+P+ V
Sbjct: 148 LEQLFSQYGRIITSRILVDQVTGVSRGVGFIRFDKRIEAEEAIKGLNGQKPSGATEPITV 207
Query: 366 ALAQRKEER--QAHLTNQYMQRMASVRAVPNPV 396
A ++ QA L+ Y + R P P+
Sbjct: 208 KFANNPSQKSSQALLSQLY---QSPNRRYPGPL 237
Score = 49.3 bits (116), Expect = 1e-05
Identities = 30/83 (36%), Positives = 42/83 (50%), Gaps = 3/83 (3%)
Query: 101 IFIKNLDKSIDNKALYDTFSAFGNILSCKVVCD--ENGSKGYGFVHFETQEAAERAIEKM 158
IF+ NL D L+ F FG + + KV+ D N KG+GFV + A AI +
Sbjct: 299 IFVYNLSPDSDESVLWQLFGPFGAVNNVKVIRDFNTNKCKGFGFVTMTNYDEAAMAIASL 358
Query: 159 NGMLLNDRKVFVGRFKSRKEREA 181
NG L DR + V FK+ K ++
Sbjct: 359 NGYRLGDRVLQVS-FKTNKAHKS 380
Score = 45.4 bits (106), Expect = 2e-04
Identities = 29/96 (30%), Positives = 51/96 (53%), Gaps = 3/96 (3%)
Query: 3 PSAPSYPMASLYVGDLHPDVTEAMLYEKFSPAGPILSIRVCRDMITRRSLGYAYVNFQQP 62
PS+ S A+LYV L +T+ L + FS G I++ R+ D +T S G ++ F +
Sbjct: 124 PSSASIRDANLYVSGLPKTMTQKELEQLFSQYGRIITSRILVDQVTGVSRGVGFIRFDKR 183
Query: 63 ADAERALDTMNFDVIKG--KPVRIMWSQRDPSLRKS 96
+AE A+ +N G +P+ + ++ +PS + S
Sbjct: 184 IEAEEAIKGLNGQKPSGATEPITVKFA-NNPSQKSS 218
Score = 42.0 bits (97), Expect = 0.002
Identities = 18/61 (29%), Positives = 36/61 (59%)
Query: 13 LYVGDLHPDVTEAMLYEKFSPAGPILSIRVCRDMITRRSLGYAYVNFQQPADAERALDTM 72
++V +L PD E++L++ F P G + +++V RD T + G+ +V +A A+ ++
Sbjct: 299 IFVYNLSPDSDESVLWQLFGPFGAVNNVKVIRDFNTNKCKGFGFVTMTNYDEAAMAIASL 358
Query: 73 N 73
N
Sbjct: 359 N 359
>gi|209862867 poly-U binding splicing factor 60KDa isoform c [Homo
sapiens]
Length = 516
Score = 98.2 bits (243), Expect = 2e-20
Identities = 64/214 (29%), Positives = 115/214 (53%), Gaps = 11/214 (5%)
Query: 60 QQPADAERALDTMNF-DVIKGKPVRIMWSQRDPSLRKSGVGNIFIKNLDKSIDNKALYDT 118
QQ + + A TM F D + P++ M +QR +L + + +++ ++ + +
Sbjct: 50 QQLTNLQMAAVTMGFGDPLS--PLQSMAAQRQRAL--AIMCRVYVGSIYYELGEDTIRQA 105
Query: 119 FSAFGNILSCKVVCDE--NGSKGYGFVHFETQEAAERAIEKMNGMLLNDRKVFVGRFKSR 176
F+ FG I S + D KG+ FV +E EAA+ A+E+MN ++L R + VGR +
Sbjct: 106 FAPFGPIKSIDMSWDSVTMKHKGFAFVEYEVPEAAQLALEQMNSVMLGGRNIKVGRPSNI 165
Query: 177 KEREA---ELGARAKEFTNVYIKNFGEDMDDERLKDLFGKFGPALSVKVMTDES-GKSKG 232
+ + +L A+ F +Y+ + +D+ D+ +K +F FG S + D + GK KG
Sbjct: 166 GQAQPIIDQLAEEARAFNRIYVASVHQDLSDDDIKSVFEAFGKIKSCTLARDPTTGKHKG 225
Query: 233 FGFVSFERHEDAQKAVDEMNGKELNGKQIYVGRA 266
+GF+ +E+ + +Q AV MN +L G+ + VG+A
Sbjct: 226 YGFIEYEKAQSSQDAVSSMNLFDLGGQYLRVGKA 259
Score = 82.0 bits (201), Expect = 2e-15
Identities = 47/174 (27%), Positives = 90/174 (51%), Gaps = 11/174 (6%)
Query: 10 MASLYVGDLHPDVTEAMLYEKFSPAGPILSIRVCRDMITRRSLGYAYVNFQQPADAERAL 69
M +YVG ++ ++ E + + F+P GPI SI + D +T + G+A+V ++ P A+ AL
Sbjct: 85 MCRVYVGSIYYELGEDTIRQAFAPFGPIKSIDMSWDSVTMKHKGFAFVEYEVPEAAQLAL 144
Query: 70 DTMNFDVIKGKPVRI----MWSQRDPSL-----RKSGVGNIFIKNLDKSIDNKALYDTFS 120
+ MN ++ G+ +++ Q P + I++ ++ + + + + F
Sbjct: 145 EQMNSVMLGGRNIKVGRPSNIGQAQPIIDQLAEEARAFNRIYVASVHQDLSDDDIKSVFE 204
Query: 121 AFGNILSCKVVCDENGS--KGYGFVHFETQEAAERAIEKMNGMLLNDRKVFVGR 172
AFG I SC + D KGYGF+ +E ++++ A+ MN L + + VG+
Sbjct: 205 AFGKIKSCTLARDPTTGKHKGYGFIEYEKAQSSQDAVSSMNLFDLGGQYLRVGK 258
Score = 81.6 bits (200), Expect = 2e-15
Identities = 107/436 (24%), Positives = 170/436 (38%), Gaps = 112/436 (25%)
Query: 193 VYIKNFGEDMDDERLKDLFGKFGPALSVKVMTDE-SGKSKGFGFVSFERHEDAQKAVDEM 251
VY+ + ++ ++ ++ F FGP S+ + D + K KGF FV +E E AQ A+++M
Sbjct: 88 VYVGSIYYELGEDTIRQAFAPFGPIKSIDMSWDSVTMKHKGFAFVEYEVPEAAQLALEQM 147
Query: 252 NGKELNGKQIYVGR------AQKKVERQTELKRKFEQMKQDRITRYQGVNLYVKNLDDGI 305
N L G+ I VGR AQ +++ E R F + +YV ++ +
Sbjct: 148 NSVMLGGRNIKVGRPSNIGQAQPIIDQLAEEARAFNR-------------IYVASVHQDL 194
Query: 306 DDERLRKEFSPFGTITSAKVMME--GGRSKGFGFVCFSSPEEATKAVTEMNGRIVATKPL 363
D+ ++ F FG I S + + G+ KG+GF+ + + + AV+ MN
Sbjct: 195 SDDDIKSVFEAFGKIKSCTLARDPTTGKHKGYGFIEYEKAQSSQDAVSSMN--------- 245
Query: 364 YVALAQRKEERQAHLTNQYMQRMASVRAVPNPVINPYQPAPPSGYFMAAIPQTQNRAAYY 423
L QY+ R+ P P++ PA P G +P
Sbjct: 246 -----------LFDLGGQYL-RVGKAVTPPMPLLT---PATPGG-----LP--------- 276
Query: 424 PPSQIAQLRPSPRWTAQ----GARPHPFQNMPGAIRPAAPRPPFSTMRPASSQVPRVMST 479
P + +A + + TAQ GA PG + PA
Sbjct: 277 PAAAVAAAAATAKITAQEAVAGAAVLGTLGTPGLVSPAL--------------------- 315
Query: 480 QRVANTSTQTMGPRPAAAAAAATPAVRTVPQYKYAAGVRNPQQHLNAQPQVTMQQPAVHV 539
T Q +G P A AA P V T GV A+P + + P+V V
Sbjct: 316 -----TLAQPLGTLPQAVMAAQAPGVIT--------GV------TPARPPIPVTIPSVGV 356
Query: 540 QGQEPLTASMLASAPPQEQKQMLGERLFPLIQAMHPTLAGKITGMLLEIDNSELLHMLES 599
P+ AS + +K+ E LFP ++ P + + M I S HM+
Sbjct: 357 --VNPILASPPTLGLLEPKKEKEEEELFP--ESERPEMLSEQEHM--SISGSSARHMV-- 408
Query: 600 PESLRSKVDEAVAVLQ 615
+ L K + V VL+
Sbjct: 409 MQKLLRKQESTVMVLR 424
Score = 30.4 bits (67), Expect = 5.2
Identities = 21/86 (24%), Positives = 42/86 (48%), Gaps = 10/86 (11%)
Query: 186 RAKEFTNVYIKNFGE--DMDDE---RLKDLFGKFGPALSVKVMTDESGKSKGFG-----F 235
R +E T + ++N + D+DD+ + + GKFG V + ++ G+ + F
Sbjct: 414 RKQESTVMVLRNMVDPKDIDDDLEGEVTEECGKFGAVNRVIIYQEKQGEEEDAEIIVKIF 473
Query: 236 VSFERHEDAQKAVDEMNGKELNGKQI 261
V F + KA+ +NG+ G+++
Sbjct: 474 VEFSIASETHKAIQALNGRWFAGRKV 499
>gi|17978512 poly-U binding splicing factor 60KDa isoform a [Homo
sapiens]
Length = 559
Score = 98.2 bits (243), Expect = 2e-20
Identities = 64/214 (29%), Positives = 115/214 (53%), Gaps = 11/214 (5%)
Query: 60 QQPADAERALDTMNF-DVIKGKPVRIMWSQRDPSLRKSGVGNIFIKNLDKSIDNKALYDT 118
QQ + + A TM F D + P++ M +QR +L + + +++ ++ + +
Sbjct: 93 QQLTNLQMAAVTMGFGDPLS--PLQSMAAQRQRAL--AIMCRVYVGSIYYELGEDTIRQA 148
Query: 119 FSAFGNILSCKVVCDE--NGSKGYGFVHFETQEAAERAIEKMNGMLLNDRKVFVGRFKSR 176
F+ FG I S + D KG+ FV +E EAA+ A+E+MN ++L R + VGR +
Sbjct: 149 FAPFGPIKSIDMSWDSVTMKHKGFAFVEYEVPEAAQLALEQMNSVMLGGRNIKVGRPSNI 208
Query: 177 KEREA---ELGARAKEFTNVYIKNFGEDMDDERLKDLFGKFGPALSVKVMTDES-GKSKG 232
+ + +L A+ F +Y+ + +D+ D+ +K +F FG S + D + GK KG
Sbjct: 209 GQAQPIIDQLAEEARAFNRIYVASVHQDLSDDDIKSVFEAFGKIKSCTLARDPTTGKHKG 268
Query: 233 FGFVSFERHEDAQKAVDEMNGKELNGKQIYVGRA 266
+GF+ +E+ + +Q AV MN +L G+ + VG+A
Sbjct: 269 YGFIEYEKAQSSQDAVSSMNLFDLGGQYLRVGKA 302
Score = 82.0 bits (201), Expect = 2e-15
Identities = 47/174 (27%), Positives = 90/174 (51%), Gaps = 11/174 (6%)
Query: 10 MASLYVGDLHPDVTEAMLYEKFSPAGPILSIRVCRDMITRRSLGYAYVNFQQPADAERAL 69
M +YVG ++ ++ E + + F+P GPI SI + D +T + G+A+V ++ P A+ AL
Sbjct: 128 MCRVYVGSIYYELGEDTIRQAFAPFGPIKSIDMSWDSVTMKHKGFAFVEYEVPEAAQLAL 187
Query: 70 DTMNFDVIKGKPVRI----MWSQRDPSL-----RKSGVGNIFIKNLDKSIDNKALYDTFS 120
+ MN ++ G+ +++ Q P + I++ ++ + + + + F
Sbjct: 188 EQMNSVMLGGRNIKVGRPSNIGQAQPIIDQLAEEARAFNRIYVASVHQDLSDDDIKSVFE 247
Query: 121 AFGNILSCKVVCDENGS--KGYGFVHFETQEAAERAIEKMNGMLLNDRKVFVGR 172
AFG I SC + D KGYGF+ +E ++++ A+ MN L + + VG+
Sbjct: 248 AFGKIKSCTLARDPTTGKHKGYGFIEYEKAQSSQDAVSSMNLFDLGGQYLRVGK 301
Score = 81.6 bits (200), Expect = 2e-15
Identities = 107/436 (24%), Positives = 170/436 (38%), Gaps = 112/436 (25%)
Query: 193 VYIKNFGEDMDDERLKDLFGKFGPALSVKVMTDE-SGKSKGFGFVSFERHEDAQKAVDEM 251
VY+ + ++ ++ ++ F FGP S+ + D + K KGF FV +E E AQ A+++M
Sbjct: 131 VYVGSIYYELGEDTIRQAFAPFGPIKSIDMSWDSVTMKHKGFAFVEYEVPEAAQLALEQM 190
Query: 252 NGKELNGKQIYVGR------AQKKVERQTELKRKFEQMKQDRITRYQGVNLYVKNLDDGI 305
N L G+ I VGR AQ +++ E R F + +YV ++ +
Sbjct: 191 NSVMLGGRNIKVGRPSNIGQAQPIIDQLAEEARAFNR-------------IYVASVHQDL 237
Query: 306 DDERLRKEFSPFGTITSAKVMME--GGRSKGFGFVCFSSPEEATKAVTEMNGRIVATKPL 363
D+ ++ F FG I S + + G+ KG+GF+ + + + AV+ MN
Sbjct: 238 SDDDIKSVFEAFGKIKSCTLARDPTTGKHKGYGFIEYEKAQSSQDAVSSMN--------- 288
Query: 364 YVALAQRKEERQAHLTNQYMQRMASVRAVPNPVINPYQPAPPSGYFMAAIPQTQNRAAYY 423
L QY+ R+ P P++ PA P G +P
Sbjct: 289 -----------LFDLGGQYL-RVGKAVTPPMPLLT---PATPGG-----LP--------- 319
Query: 424 PPSQIAQLRPSPRWTAQ----GARPHPFQNMPGAIRPAAPRPPFSTMRPASSQVPRVMST 479
P + +A + + TAQ GA PG + PA
Sbjct: 320 PAAAVAAAAATAKITAQEAVAGAAVLGTLGTPGLVSPAL--------------------- 358
Query: 480 QRVANTSTQTMGPRPAAAAAAATPAVRTVPQYKYAAGVRNPQQHLNAQPQVTMQQPAVHV 539
T Q +G P A AA P V T GV A+P + + P+V V
Sbjct: 359 -----TLAQPLGTLPQAVMAAQAPGVIT--------GV------TPARPPIPVTIPSVGV 399
Query: 540 QGQEPLTASMLASAPPQEQKQMLGERLFPLIQAMHPTLAGKITGMLLEIDNSELLHMLES 599
P+ AS + +K+ E LFP ++ P + + M I S HM+
Sbjct: 400 --VNPILASPPTLGLLEPKKEKEEEELFP--ESERPEMLSEQEHM--SISGSSARHMV-- 451
Query: 600 PESLRSKVDEAVAVLQ 615
+ L K + V VL+
Sbjct: 452 MQKLLRKQESTVMVLR 467
Score = 30.4 bits (67), Expect = 5.2
Identities = 21/86 (24%), Positives = 42/86 (48%), Gaps = 10/86 (11%)
Query: 186 RAKEFTNVYIKNFGE--DMDDE---RLKDLFGKFGPALSVKVMTDESGKSKGFG-----F 235
R +E T + ++N + D+DD+ + + GKFG V + ++ G+ + F
Sbjct: 457 RKQESTVMVLRNMVDPKDIDDDLEGEVTEECGKFGAVNRVIIYQEKQGEEEDAEIIVKIF 516
Query: 236 VSFERHEDAQKAVDEMNGKELNGKQI 261
V F + KA+ +NG+ G+++
Sbjct: 517 VEFSIASETHKAIQALNGRWFAGRKV 542
>gi|17298690 poly-U binding splicing factor 60KDa isoform b [Homo
sapiens]
Length = 542
Score = 94.4 bits (233), Expect = 3e-19
Identities = 52/172 (30%), Positives = 94/172 (54%), Gaps = 6/172 (3%)
Query: 101 IFIKNLDKSIDNKALYDTFSAFGNILSCKVVCDE--NGSKGYGFVHFETQEAAERAIEKM 158
+++ ++ + + F+ FG I S + D KG+ FV +E EAA+ A+E+M
Sbjct: 114 VYVGSIYYELGEDTIRQAFAPFGPIKSIDMSWDSVTMKHKGFAFVEYEVPEAAQLALEQM 173
Query: 159 NGMLLNDRKVFVGRFKSRKEREA---ELGARAKEFTNVYIKNFGEDMDDERLKDLFGKFG 215
N ++L R + VGR + + + +L A+ F +Y+ + +D+ D+ +K +F FG
Sbjct: 174 NSVMLGGRNIKVGRPSNIGQAQPIIDQLAEEARAFNRIYVASVHQDLSDDDIKSVFEAFG 233
Query: 216 PALSVKVMTDES-GKSKGFGFVSFERHEDAQKAVDEMNGKELNGKQIYVGRA 266
S + D + GK KG+GF+ +E+ + +Q AV MN +L G+ + VG+A
Sbjct: 234 KIKSCTLARDPTTGKHKGYGFIEYEKAQSSQDAVSSMNLFDLGGQYLRVGKA 285
Score = 82.0 bits (201), Expect = 2e-15
Identities = 117/490 (23%), Positives = 194/490 (39%), Gaps = 121/490 (24%)
Query: 146 ETQEAAERAIEKMNGMLLNDRKVFVGRFKSRKEREA---ELGARAKE----FTNVYIKNF 198
E QEA ++A K M + + V V + + ++++ ++ A+ + VY+ +
Sbjct: 62 EQQEALQKA--KKYAMEQSIKSVLVKQTIAHQQQQLTNLQMAAQRQRALAIMCRVYVGSI 119
Query: 199 GEDMDDERLKDLFGKFGPALSVKVMTDE-SGKSKGFGFVSFERHEDAQKAVDEMNGKELN 257
++ ++ ++ F FGP S+ + D + K KGF FV +E E AQ A+++MN L
Sbjct: 120 YYELGEDTIRQAFAPFGPIKSIDMSWDSVTMKHKGFAFVEYEVPEAAQLALEQMNSVMLG 179
Query: 258 GKQIYVGR------AQKKVERQTELKRKFEQMKQDRITRYQGVNLYVKNLDDGIDDERLR 311
G+ I VGR AQ +++ E R F + +YV ++ + D+ ++
Sbjct: 180 GRNIKVGRPSNIGQAQPIIDQLAEEARAFNR-------------IYVASVHQDLSDDDIK 226
Query: 312 KEFSPFGTITSAKVMME--GGRSKGFGFVCFSSPEEATKAVTEMNGRIVATKPLYVALAQ 369
F FG I S + + G+ KG+GF+ + + + AV+ MN
Sbjct: 227 SVFEAFGKIKSCTLARDPTTGKHKGYGFIEYEKAQSSQDAVSSMN--------------- 271
Query: 370 RKEERQAHLTNQYMQRMASVRAVPNPVINPYQPAPPSGYFMAAIPQTQNRAAYYPPSQIA 429
L QY+ R+ P P++ PA P G +P P + +A
Sbjct: 272 -----LFDLGGQYL-RVGKAVTPPMPLLT---PATPGG-----LP---------PAAAVA 308
Query: 430 QLRPSPRWTAQ----GARPHPFQNMPGAIRPAAPRPPFSTMRPASSQVPRVMSTQRVANT 485
+ + TAQ GA PG + PA T
Sbjct: 309 AAAATAKITAQEAVAGAAVLGTLGTPGLVSPAL--------------------------T 342
Query: 486 STQTMGPRPAAAAAAATPAVRTVPQYKYAAGVRNPQQHLNAQPQVTMQQPAVHVQGQEPL 545
Q +G P A AA P V T GV A+P + + P+V V P+
Sbjct: 343 LAQPLGTLPQAVMAAQAPGVIT--------GV------TPARPPIPVTIPSVGV--VNPI 386
Query: 546 TASMLASAPPQEQKQMLGERLFPLIQAMHPTLAGKITGMLLEIDNSELLHMLESPESLRS 605
AS + +K+ E LFP ++ P + + M I S HM+ + L
Sbjct: 387 LASPPTLGLLEPKKEKEEEELFP--ESERPEMLSEQEHM--SISGSSARHMV--MQKLLR 440
Query: 606 KVDEAVAVLQ 615
K + V VL+
Sbjct: 441 KQESTVMVLR 450
Score = 82.0 bits (201), Expect = 2e-15
Identities = 47/174 (27%), Positives = 90/174 (51%), Gaps = 11/174 (6%)
Query: 10 MASLYVGDLHPDVTEAMLYEKFSPAGPILSIRVCRDMITRRSLGYAYVNFQQPADAERAL 69
M +YVG ++ ++ E + + F+P GPI SI + D +T + G+A+V ++ P A+ AL
Sbjct: 111 MCRVYVGSIYYELGEDTIRQAFAPFGPIKSIDMSWDSVTMKHKGFAFVEYEVPEAAQLAL 170
Query: 70 DTMNFDVIKGKPVRI----MWSQRDPSL-----RKSGVGNIFIKNLDKSIDNKALYDTFS 120
+ MN ++ G+ +++ Q P + I++ ++ + + + + F
Sbjct: 171 EQMNSVMLGGRNIKVGRPSNIGQAQPIIDQLAEEARAFNRIYVASVHQDLSDDDIKSVFE 230
Query: 121 AFGNILSCKVVCDENGS--KGYGFVHFETQEAAERAIEKMNGMLLNDRKVFVGR 172
AFG I SC + D KGYGF+ +E ++++ A+ MN L + + VG+
Sbjct: 231 AFGKIKSCTLARDPTTGKHKGYGFIEYEKAQSSQDAVSSMNLFDLGGQYLRVGK 284
Score = 30.4 bits (67), Expect = 5.2
Identities = 21/86 (24%), Positives = 42/86 (48%), Gaps = 10/86 (11%)
Query: 186 RAKEFTNVYIKNFGE--DMDDE---RLKDLFGKFGPALSVKVMTDESGKSKGFG-----F 235
R +E T + ++N + D+DD+ + + GKFG V + ++ G+ + F
Sbjct: 440 RKQESTVMVLRNMVDPKDIDDDLEGEVTEECGKFGAVNRVIIYQEKQGEEEDAEIIVKIF 499
Query: 236 VSFERHEDAQKAVDEMNGKELNGKQI 261
V F + KA+ +NG+ G+++
Sbjct: 500 VEFSIASETHKAIQALNGRWFAGRKV 525
>gi|8400718 RNA binding motif, single stranded interacting protein 1
isoform a [Homo sapiens]
Length = 406
Score = 90.5 bits (223), Expect = 4e-18
Identities = 91/374 (24%), Positives = 151/374 (40%), Gaps = 64/374 (17%)
Query: 191 TNVYIKNFGEDMDDERLKDLFGKFGPALSVKVMTDES-GKSKGFGFVSFERHEDAQKAVD 249
TN+YI+ D+ L L +G +S K + D++ K KG+GFV F+ AQKAV
Sbjct: 62 TNLYIRGLPPHTTDQDLVKLCQPYGKIVSTKAILDKTTNKCKGYGFVDFDSPAAAQKAVS 121
Query: 250 EMNGKELNGKQIYVGRAQKKVERQTELKRKFEQMKQDRITRYQGVNLYVKNLDDGIDDER 309
+ + + +Q +QD NLY+ NL +D++
Sbjct: 122 ALKASGVQAQMA-------------------KQQEQDP------TNLYISNLPLSMDEQE 156
Query: 310 LRKEFSPFGTITSAKVMME-GGRSKGFGFVCFSSPEEATKAVTEMNGRIV--------AT 360
L PFG + S +++ + G S+G GF S E+ + NG+ + T
Sbjct: 157 LENMLKPFGQVISTRILRDSSGTSRGVGFARMESTEKCEAVIGHFNGKFIKTPPGVSAPT 216
Query: 361 KPLYVALAQRKEERQAHLTNQYMQ-----------RMASVRAVPNP----VINPYQPAPP 405
+PL A ++++ + N+Y+ R+A + +P + N + P+P
Sbjct: 217 EPLLCKFADGGQKKRQN-PNKYIPNGRPWHREGEVRLAGMTLTYDPTTAAIQNGFYPSPY 275
Query: 406 SGYFMAAIPQTQNRAAYYPPSQIAQLRPSPRWTAQGARPHPF-QNMPGAIRPAAPRPPFS 464
S I QT P Q++ SP W +P P+ PGA+ + S
Sbjct: 276 SIATNRMITQTSITPYIASPVSAYQVQ-SPSW----MQPQPYILQHPGAVLTPSMEHTMS 330
Query: 465 TMRPASSQVPRVMSTQRVANTSTQTMGPRPAAAAAAATPAVRTVPQYKYAAGVRNPQQHL 524
++PAS P ++ ST T P +A A +PQY + P +
Sbjct: 331 -LQPASMISPLAQQMSHLSLGSTGTYMPATSAMQGA------YLPQYAHMQTTAVPVEEA 383
Query: 525 NAQPQVTMQQPAVH 538
+ Q QV ++ H
Sbjct: 384 SGQQQVAVETSNDH 397
Score = 80.1 bits (196), Expect = 6e-15
Identities = 50/187 (26%), Positives = 90/187 (48%), Gaps = 10/187 (5%)
Query: 12 SLYVGDLHPDVTEAMLYEKFSPAGPILSIRVCRDMITRRSLGYAYVNFQQPADAERALDT 71
+LY+ L P T+ L + P G I+S + D T + GY +V+F PA A++A+
Sbjct: 63 NLYIRGLPPHTTDQDLVKLCQPYGKIVSTKAILDKTTNKCKGYGFVDFDSPAAAQKAVSA 122
Query: 72 MNFDVIKGKPVRIMWSQRDPSLRKSGVGNIFIKNLDKSIDNKALYDTFSAFGNILSCKVV 131
+ ++ + + ++DP+ N++I NL S+D + L + FG ++S +++
Sbjct: 123 LKASGVQAQMAK--QQEQDPT-------NLYISNLPLSMDEQELENMLKPFGQVISTRIL 173
Query: 132 CDENG-SKGYGFVHFETQEAAERAIEKMNGMLLNDRKVFVGRFKSRKEREAELGARAKEF 190
D +G S+G GF E+ E E I NG + + + A+ G + ++
Sbjct: 174 RDSSGTSRGVGFARMESTEKCEAVIGHFNGKFIKTPPGVSAPTEPLLCKFADGGQKKRQN 233
Query: 191 TNVYIKN 197
N YI N
Sbjct: 234 PNKYIPN 240
Score = 79.7 bits (195), Expect = 7e-15
Identities = 46/157 (29%), Positives = 80/157 (50%), Gaps = 17/157 (10%)
Query: 100 NIFIKNLDKSIDNKALYDTFSAFGNILSCKVVCDE--NGSKGYGFVHFETQEAAERAIEK 157
N++I+ L ++ L +G I+S K + D+ N KGYGFV F++ AA++A+
Sbjct: 63 NLYIRGLPPHTTDQDLVKLCQPYGKIVSTKAILDKTTNKCKGYGFVDFDSPAAAQKAVSA 122
Query: 158 MNGMLLNDRKVFVGRFKSRKEREAELGARAKEFTNVYIKNFGEDMDDERLKDLFGKFGPA 217
+ K + + K++E ++ TN+YI N MD++ L+++ FG
Sbjct: 123 L--------KASGVQAQMAKQQE-------QDPTNLYISNLPLSMDEQELENMLKPFGQV 167
Query: 218 LSVKVMTDESGKSKGFGFVSFERHEDAQKAVDEMNGK 254
+S +++ D SG S+G GF E E + + NGK
Sbjct: 168 ISTRILRDSSGTSRGVGFARMESTEKCEAVIGHFNGK 204
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.316 0.131 0.376
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 24,547,208
Number of Sequences: 37866
Number of extensions: 1214163
Number of successful extensions: 8267
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 263
Number of HSP's successfully gapped in prelim test: 430
Number of HSP's that attempted gapping in prelim test: 5639
Number of HSP's gapped (non-prelim): 2003
length of query: 636
length of database: 18,247,518
effective HSP length: 109
effective length of query: 527
effective length of database: 14,120,124
effective search space: 7441305348
effective search space used: 7441305348
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.