Guide to the Human Genome
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Search of human proteins with 46276863

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|46276863 parathymosin [Homo sapiens]
         (102 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|46276863 parathymosin [Homo sapiens]                               198   7e-52
gi|151101404 prothymosin, alpha isoform 2 [Homo sapiens]               82   7e-17
gi|151101407 prothymosin, alpha isoform 1 [Homo sapiens]               82   9e-17
gi|113420848 PREDICTED: hypothetical protein [Homo sapiens]            82   1e-16
gi|169217548 PREDICTED: hypothetical protein [Homo sapiens]            80   3e-16
gi|239752637 PREDICTED: hypothetical protein [Homo sapiens]            80   3e-16
gi|113420837 PREDICTED: hypothetical protein [Homo sapiens]            80   3e-16
gi|17975763 myelin transcription factor 1 [Homo sapiens]               65   1e-11
gi|78190492 retinitis pigmentosa GTPase regulator isoform C [Hom...    64   2e-11
gi|239508778 PREDICTED: hypothetical protein, partial [Homo sapi...    62   1e-10
gi|94536805 splicing factor YT521-B isoform 2 [Homo sapiens]           60   3e-10
gi|72534750 splicing factor YT521-B isoform 1 [Homo sapiens]           60   3e-10
gi|155030232 proline, glutamic acid and leucine rich protein 1 [...    60   5e-10
gi|239745093 PREDICTED: hypothetical protein XP_002343359 [Homo ...    59   8e-10
gi|169210053 PREDICTED: hypothetical protein [Homo sapiens]            58   2e-09
gi|221219020 NYD-SP11 protein [Homo sapiens]                           57   2e-09
gi|105990539 neurofilament, light polypeptide 68kDa [Homo sapiens]     57   2e-09
gi|157738649 neurofilament, medium polypeptide 150kDa isoform 1 ...    57   3e-09
gi|157738641 neurofilament, medium polypeptide 150kDa isoform 2 ...    57   3e-09
gi|195546902 suppressor of Ty 5 homolog isoform b [Homo sapiens]       57   4e-09
gi|195546900 suppressor of Ty 5 homolog isoform a [Homo sapiens]       57   4e-09
gi|161169023 suppressor of Ty 5 homolog isoform a [Homo sapiens]       57   4e-09
gi|20149524 suppressor of Ty 5 homolog isoform a [Homo sapiens]        57   4e-09
gi|84043963 eukaryotic translation initiation factor 5B [Homo sa...    57   4e-09
gi|28274705 family with sequence similarity 9, member A [Homo sa...    57   4e-09
gi|239050813 lipoxygenase homology domains 1 isoform 1 [Homo sap...    56   5e-09
gi|4504425 high-mobility group box 1 [Homo sapiens]                    56   7e-09
gi|66792814 retrotransposon gag domain containing 4 [Homo sapiens]     56   7e-09
gi|21735415 centromere protein B [Homo sapiens]                        55   9e-09
gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens]     55   9e-09

>gi|46276863 parathymosin [Homo sapiens]
          Length = 102

 Score =  198 bits (504), Expect = 7e-52
 Identities = 102/102 (100%), Positives = 102/102 (100%)

Query: 1   MSEKSVEAAAELSAKDLKEKKEKVEEKASRKERKKEVVEEEENGAEEEEEETAEDGEEED 60
           MSEKSVEAAAELSAKDLKEKKEKVEEKASRKERKKEVVEEEENGAEEEEEETAEDGEEED
Sbjct: 1   MSEKSVEAAAELSAKDLKEKKEKVEEKASRKERKKEVVEEEENGAEEEEEETAEDGEEED 60

Query: 61  EGEEEDEEEEEEDDEGPALKRAAEEEDEADPKRQKTENGASA 102
           EGEEEDEEEEEEDDEGPALKRAAEEEDEADPKRQKTENGASA
Sbjct: 61  EGEEEDEEEEEEDDEGPALKRAAEEEDEADPKRQKTENGASA 102


>gi|151101404 prothymosin, alpha isoform 2 [Homo sapiens]
          Length = 110

 Score = 82.4 bits (202), Expect = 7e-17
 Identities = 47/107 (43%), Positives = 70/107 (65%), Gaps = 10/107 (9%)

Query: 1   MSEKSVEAAAELSAKDLKEKKEKVEEKASRKERKKEVVEEEENG-------AEEEEEETA 53
           MS+ +V+ ++E++ KDLKEKKE VEE  + ++        EENG        +EEEEE  
Sbjct: 1   MSDAAVDTSSEITTKDLKEKKEVVEEAENGRDAPANGNANEENGEQEADNEVDEEEEEGG 60

Query: 54  EDGEEEDEGE-EEDEEEEEEDDEGPALKRAAE--EEDEADPKRQKTE 97
           E+ EEE+EG+ EE++ +E+E+ E    KRAAE  E+D+ D K+QKT+
Sbjct: 61  EEEEEEEEGDGEEEDGDEDEEAESATGKRAAEDDEDDDVDTKKQKTD 107


>gi|151101407 prothymosin, alpha isoform 1 [Homo sapiens]
          Length = 111

 Score = 82.0 bits (201), Expect = 9e-17
 Identities = 46/108 (42%), Positives = 72/108 (66%), Gaps = 11/108 (10%)

Query: 1   MSEKSVEAAAELSAKDLKEKKEKVEEKASRK--------ERKKEVVEEEENGAEEEEEET 52
           MS+ +V+ ++E++ KDLKEKKE VEE  + +        E ++   +E +N  +EEEEE 
Sbjct: 1   MSDAAVDTSSEITTKDLKEKKEVVEEAENGRDAPANGNAENEENGEQEADNEVDEEEEEG 60

Query: 53  AEDGEEEDEGE-EEDEEEEEEDDEGPALKRAAE--EEDEADPKRQKTE 97
            E+ EEE+EG+ EE++ +E+E+ E    KRAAE  E+D+ D K+QKT+
Sbjct: 61  GEEEEEEEEGDGEEEDGDEDEEAESATGKRAAEDDEDDDVDTKKQKTD 108


>gi|113420848 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 109

 Score = 81.6 bits (200), Expect = 1e-16
 Identities = 46/106 (43%), Positives = 68/106 (64%), Gaps = 9/106 (8%)

Query: 1   MSEKSVEAAAELSAKDLKEKKEKVEEKASRKERKKEVVEEEENG-------AEEEEEETA 53
           MS+ +V+ ++E+ AKDLKEKKE V+E  + ++        EENG        +EE EE+ 
Sbjct: 1   MSDAAVDTSSEIIAKDLKEKKEVVKEAENGRDAPANGNANEENGEQEADKEVDEEGEESG 60

Query: 54  EDGEEEDEGEEEDEEEEEEDDEGPALKRAAE--EEDEADPKRQKTE 97
           E+ EEE EG+ E+E+ +EE+ E    KRAAE  E+D+ D K+QKT+
Sbjct: 61  EEEEEEKEGDGEEEDGDEEEAESATGKRAAEDDEDDDVDTKKQKTD 106


>gi|169217548 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 109

 Score = 80.5 bits (197), Expect = 3e-16
 Identities = 45/106 (42%), Positives = 68/106 (64%), Gaps = 9/106 (8%)

Query: 1   MSEKSVEAAAELSAKDLKEKKEKVEEKASRKERKKEVVEEEENG-------AEEEEEETA 53
           MS+ +V+ ++E+ AKDLKEKKE V++  + ++        EENG        +EE EE+ 
Sbjct: 1   MSDAAVDTSSEIIAKDLKEKKEVVKDAENGRDAPANGNANEENGEQEADNEVDEEGEESG 60

Query: 54  EDGEEEDEGEEEDEEEEEEDDEGPALKRAAE--EEDEADPKRQKTE 97
           E+ EEE EG+ E+E+ +EE+ E    KRAAE  E+D+ D K+QKT+
Sbjct: 61  EEEEEEKEGDGEEEDGDEEEAESATGKRAAEDDEDDDVDTKKQKTD 106


>gi|239752637 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 109

 Score = 80.5 bits (197), Expect = 3e-16
 Identities = 45/106 (42%), Positives = 68/106 (64%), Gaps = 9/106 (8%)

Query: 1   MSEKSVEAAAELSAKDLKEKKEKVEEKASRKERKKEVVEEEENG-------AEEEEEETA 53
           MS+ +V+ ++E+ AKDLKEKKE V++  + ++        EENG        +EE EE+ 
Sbjct: 1   MSDAAVDTSSEIIAKDLKEKKEVVKDAENGRDAPANGNANEENGEQEADNEVDEEGEESG 60

Query: 54  EDGEEEDEGEEEDEEEEEEDDEGPALKRAAE--EEDEADPKRQKTE 97
           E+ EEE EG+ E+E+ +EE+ E    KRAAE  E+D+ D K+QKT+
Sbjct: 61  EEEEEEKEGDGEEEDGDEEEAESATGKRAAEDDEDDDVDTKKQKTD 106


>gi|113420837 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 109

 Score = 80.5 bits (197), Expect = 3e-16
 Identities = 45/106 (42%), Positives = 68/106 (64%), Gaps = 9/106 (8%)

Query: 1   MSEKSVEAAAELSAKDLKEKKEKVEEKASRKERKKEVVEEEENG-------AEEEEEETA 53
           MS+ +V+ ++E+ AKDLKEKKE V++  + ++        EENG        +EE EE+ 
Sbjct: 1   MSDAAVDTSSEIIAKDLKEKKEVVKDAENGRDAPANGNANEENGEQEADNEVDEEGEESG 60

Query: 54  EDGEEEDEGEEEDEEEEEEDDEGPALKRAAE--EEDEADPKRQKTE 97
           E+ EEE EG+ E+E+ +EE+ E    KRAAE  E+D+ D K+QKT+
Sbjct: 61  EEEEEEKEGDGEEEDGDEEEAESATGKRAAEDDEDDDVDTKKQKTD 106


>gi|17975763 myelin transcription factor 1 [Homo sapiens]
          Length = 1121

 Score = 64.7 bits (156), Expect = 1e-11
 Identities = 39/90 (43%), Positives = 52/90 (57%), Gaps = 1/90 (1%)

Query: 2   SEKSVEAAAELSAKDLKEKKEKVEEKASRKERKKEVVEEEENGAEEEEEETAEDGEEEDE 61
           +E+ VE   E S     +  E    + S K++     EEE+   EEEEEE  ED EEE+E
Sbjct: 221 AEEVVEVTTERSQDLCPQSLEDAASEESSKQKGILSHEEEDEEEEEEEEEEEEDEEEEEE 280

Query: 62  GEEEDEEEEEEDDEGPALKRAAEEEDEADP 91
            EEE+EEEEEE++E    +   EEE+EA P
Sbjct: 281 EEEEEEEEEEEEEEEEE-EEEEEEEEEAAP 309



 Score = 61.6 bits (148), Expect = 1e-10
 Identities = 39/92 (42%), Positives = 55/92 (59%), Gaps = 5/92 (5%)

Query: 4   KSVEAAAELSAKDLKEKKEKVEEKASRKERKKEVVEEEENGAEEEEEETAEDGEEEDEGE 63
           +S+E AA  S +  K+K     E+   +E ++E  EEE+   EEEEEE  E+ EEE+E E
Sbjct: 238 QSLEDAA--SEESSKQKGILSHEEEDEEEEEEEEEEEED---EEEEEEEEEEEEEEEEEE 292

Query: 64  EEDEEEEEEDDEGPALKRAAEEEDEADPKRQK 95
           EE+EEEEEE++E  A      +ED +    QK
Sbjct: 293 EEEEEEEEEEEEEEAAPDVIFQEDTSHTSAQK 324



 Score = 55.8 bits (133), Expect = 7e-09
 Identities = 38/111 (34%), Positives = 56/111 (50%), Gaps = 11/111 (9%)

Query: 1   MSEKSVEAAAELSAKDLKEKKEKVEEKAS-RKERKKEVVEEEENGAEEEE---------- 49
           + E +  AA+E   K L  + E  EE      ER +++  +    A  EE          
Sbjct: 198 LQEAAEGAASEEGEKGLFIQPEDAEEVVEVTTERSQDLCPQSLEDAASEESSKQKGILSH 257

Query: 50  EETAEDGEEEDEGEEEDEEEEEEDDEGPALKRAAEEEDEADPKRQKTENGA 100
           EE  E+ EEE+E EEEDEEEEEE++E    +   EEE+E + + ++ E  A
Sbjct: 258 EEEDEEEEEEEEEEEEDEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEAA 308



 Score = 53.9 bits (128), Expect = 3e-08
 Identities = 32/90 (35%), Positives = 49/90 (54%)

Query: 2   SEKSVEAAAELSAKDLKEKKEKVEEKASRKERKKEVVEEEENGAEEEEEETAEDGEEEDE 61
           SE+S +    LS ++  E++E+ EE+    E ++E  EEEE   EEEEEE  E+ EEE+E
Sbjct: 245 SEESSKQKGILSHEEEDEEEEEEEEEEEEDEEEEEEEEEEEEEEEEEEEEEEEEEEEEEE 304

Query: 62  GEEEDEEEEEEDDEGPALKRAAEEEDEADP 91
            E   +   +ED    + ++A E      P
Sbjct: 305 EEAAPDVIFQEDTSHTSAQKAPELRGPESP 334



 Score = 39.7 bits (91), Expect = 5e-04
 Identities = 29/108 (26%), Positives = 50/108 (46%), Gaps = 12/108 (11%)

Query: 1   MSEKSVEAAAELSAKDLKEKKEKVEEKASRKERKKEVVEEEENGAEEEEEETAEDG---E 57
           +S +  +   E   ++ +E +E+ EE+   +E ++E  EEEE   EEEEEE A      +
Sbjct: 255 LSHEEEDEEEEEEEEEEEEDEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEAAPDVIFQ 314

Query: 58  EEDEGEEEDEEEEEEDDEGPALK---------RAAEEEDEADPKRQKT 96
           E+       +  E    E P+ K         R+ +++DE    R+ T
Sbjct: 315 EDTSHTSAQKAPELRGPESPSPKPEYSVIVEVRSDDDKDEDTHSRKST 362


>gi|78190492 retinitis pigmentosa GTPase regulator isoform C [Homo
           sapiens]
          Length = 1152

 Score = 64.3 bits (155), Expect = 2e-11
 Identities = 39/110 (35%), Positives = 61/110 (55%), Gaps = 15/110 (13%)

Query: 3   EKSVEAAAELSAKDLKEKKEKVEEKASRKERKKEVVE---------EEENGAEEEEEETA 53
           EK +    E   +D +E+++K  E+  +KER +E+ E         EEE G  EEEEE  
Sbjct: 693 EKELAEKEEWKKRDGEEQEQKEREQGHQKERNQEMEEGGEEEHGEGEEEEGDREEEEEKE 752

Query: 54  EDGEEEDEGEEEDEEEEEEDDEGPALKRAAEEE------DEADPKRQKTE 97
            +G+EE EGEE + E E+E+ E    +RA +EE      D+ + + ++TE
Sbjct: 753 GEGKEEGEGEEVEGEREKEEGERKKEERAGKEEKGEEEGDQGEGEEEETE 802



 Score = 58.5 bits (140), Expect = 1e-09
 Identities = 35/91 (38%), Positives = 47/91 (51%)

Query: 7    EAAAELSAKDLKEKKEKVEEKASRKERKKEVVEEEENGAEEEEEETAEDGEEEDEGEEED 66
            E   E   ++ + + E  EE     E  +   EEEE   E EEEE  E+GEEE EGEEE 
Sbjct: 950  EEEGEWEGEEEEGEGEGEEEGEGEGEEGEGEGEEEEGEGEGEEEEGEEEGEEEGEGEEEG 1009

Query: 67   EEEEEEDDEGPALKRAAEEEDEADPKRQKTE 97
            E E EE++EG        EE E + + ++ E
Sbjct: 1010 EGEGEEEEEGEVEGEVEGEEGEGEGEEEEGE 1040



 Score = 55.1 bits (131), Expect = 1e-08
 Identities = 39/116 (33%), Positives = 58/116 (50%), Gaps = 19/116 (16%)

Query: 3   EKSVEAAAELSAKDLKEKKEKVEEKASRKER--KKEVVEEEENGAEEEEEETAEDGEEED 60
           EK  E   E   ++++ ++EK E +  ++ER  K+E  EEE +  E EEEET   GEE++
Sbjct: 750 EKEGEGKEEGEGEEVEGEREKEEGERKKEERAGKEEKGEEEGDQGEGEEEETEGRGEEKE 809

Query: 61  EG-----------------EEEDEEEEEEDDEGPALKRAAEEEDEADPKRQKTENG 99
           EG                 EEE+ E EEE+ EG   +   EEE+      ++ E G
Sbjct: 810 EGGEVEGGEVEEGKGEREEEEEEGEGEEEEGEGEEEEGEGEEEEGEGKGEEEGEEG 865



 Score = 54.7 bits (130), Expect = 2e-08
 Identities = 33/80 (41%), Positives = 48/80 (60%), Gaps = 1/80 (1%)

Query: 18   KEKKEKVEEKASRKERKKEVVEEEENGAEEEEEETAE-DGEEEDEGEEEDEEEEEEDDEG 76
            +E +E+ EE+   +E  +   EEEE G  E E E  E +GE E+E  EE+ EE E++ EG
Sbjct: 993  EEGEEEGEEEGEGEEEGEGEGEEEEEGEVEGEVEGEEGEGEGEEEEGEEEGEEREKEGEG 1052

Query: 77   PALKRAAEEEDEADPKRQKT 96
               +R  EEE+E + K Q+T
Sbjct: 1053 EENRRNREEEEEEEGKYQET 1072



 Score = 53.9 bits (128), Expect = 3e-08
 Identities = 34/100 (34%), Positives = 51/100 (51%), Gaps = 7/100 (7%)

Query: 7   EAAAELSAKDLKEKKEKVEEKASRKERKKEVVEEEENGAEEEE-------EETAEDGEEE 59
           E   E+   +++E K + EE+    E ++E  E EE   E EE       EE  E+GE E
Sbjct: 809 EEGGEVEGGEVEEGKGEREEEEEEGEGEEEEGEGEEEEGEGEEEEGEGKGEEEGEEGEGE 868

Query: 60  DEGEEEDEEEEEEDDEGPALKRAAEEEDEADPKRQKTENG 99
           +EGEE + E EEE+ EG   +    E +E + + +  E G
Sbjct: 869 EEGEEGEGEGEEEEGEGEGEEEGEGEGEEEEGEGEGEEEG 908



 Score = 52.4 bits (124), Expect = 8e-08
 Identities = 33/88 (37%), Positives = 46/88 (52%), Gaps = 6/88 (6%)

Query: 18  KEKKEKVEEKASRKERKKEVVEEEENGAEEEEEETAEDGEEEDEGEEEDEE------EEE 71
           K ++E+ EE+   +E + E  EEE  G EEE E   E+  EE EGEEE EE      EEE
Sbjct: 823 KGEREEEEEEGEGEEEEGEGEEEEGEGEEEEGEGKGEEEGEEGEGEEEGEEGEGEGEEEE 882

Query: 72  EDDEGPALKRAAEEEDEADPKRQKTENG 99
            + EG        EE+E + + ++   G
Sbjct: 883 GEGEGEEEGEGEGEEEEGEGEGEEEGEG 910



 Score = 51.2 bits (121), Expect = 2e-07
 Identities = 31/86 (36%), Positives = 43/86 (50%)

Query: 3    EKSVEAAAELSAKDLKEKKEKVEEKASRKERKKEVVEEEENGAEEEEEETAEDGEEEDEG 62
            E+  E   E    + + + E  EE+    E + E  E E  G EEE EE  E+ E+E EG
Sbjct: 993  EEGEEEGEEEGEGEEEGEGEGEEEEEGEVEGEVEGEEGEGEGEEEEGEEEGEEREKEGEG 1052

Query: 63   EEEDEEEEEEDDEGPALKRAAEEEDE 88
            EE     EEE++E    +   EEE+E
Sbjct: 1053 EENRRNREEEEEEEGKYQETGEEENE 1078



 Score = 50.4 bits (119), Expect = 3e-07
 Identities = 33/97 (34%), Positives = 51/97 (52%), Gaps = 1/97 (1%)

Query: 3    EKSVEAAAELSAKDLKEKKEKVEEKASRKERKKEVVEEEENGAEEEEEETAEDGEEEDEG 62
            E+  E   E   ++ + + E+ E +   ++ + E  EEEE   E EEEE   +GEEE EG
Sbjct: 914  EEEGEGKGEEEGEEGEGEGEEEEGEGEGEDGEGEG-EEEEGEWEGEEEEGEGEGEEEGEG 972

Query: 63   EEEDEEEEEEDDEGPALKRAAEEEDEADPKRQKTENG 99
            E E+ E E E++EG       E E+E + + +  E G
Sbjct: 973  EGEEGEGEGEEEEGEGEGEEEEGEEEGEEEGEGEEEG 1009



 Score = 50.1 bits (118), Expect = 4e-07
 Identities = 35/103 (33%), Positives = 49/103 (47%), Gaps = 6/103 (5%)

Query: 3   EKSVEAAAELSAKDLKEKKEKVEEKASRKERKKEVVEEEENGAEEEEEETAEDGEEEDEG 62
           E+  E   E   ++ + ++E  E +   +E + E   EEE   E EEEE   +GEEE EG
Sbjct: 851 EEEGEGKGEEEGEEGEGEEEGEEGEGEGEEEEGEGEGEEEGEGEGEEEEGEGEGEEEGEG 910

Query: 63  EEEDE------EEEEEDDEGPALKRAAEEEDEADPKRQKTENG 99
           E E+E      EEE E+ EG   +   E E E      + E G
Sbjct: 911 EGEEEEGEGKGEEEGEEGEGEGEEEEGEGEGEDGEGEGEEEEG 953



 Score = 48.9 bits (115), Expect = 9e-07
 Identities = 34/89 (38%), Positives = 47/89 (52%), Gaps = 9/89 (10%)

Query: 18  KEKKEKVEEKASRKERKKEVVEEEENGAEEEE------EETAEDGE---EEDEGEEEDEE 68
           +E+ E  EE+   +E + E  EEE  G  EEE      EE  E+GE   EE+EGE E EE
Sbjct: 830 EEEGEGEEEEGEGEEEEGEGEEEEGEGKGEEEGEEGEGEEEGEEGEGEGEEEEGEGEGEE 889

Query: 69  EEEEDDEGPALKRAAEEEDEADPKRQKTE 97
           E E + E    +   EEE E + + ++ E
Sbjct: 890 EGEGEGEEEEGEGEGEEEGEGEGEEEEGE 918



 Score = 48.5 bits (114), Expect = 1e-06
 Identities = 38/104 (36%), Positives = 52/104 (50%), Gaps = 9/104 (8%)

Query: 3   EKSVEAAAELSAKDLKEKKEKVEEKASRKERKKEVVEEEENGAEEE-----EEETAEDGE 57
           E+  E   E    + +E + K EE+    E ++E  E E  G EEE     EEE   +GE
Sbjct: 837 EEEGEGEEEEGEGEEEEGEGKGEEEGEEGEGEEEGEEGEGEGEEEEGEGEGEEEGEGEGE 896

Query: 58  EED---EGEEEDE-EEEEEDDEGPALKRAAEEEDEADPKRQKTE 97
           EE+   EGEEE E E EEE+ EG   +   E E E + +  + E
Sbjct: 897 EEEGEGEGEEEGEGEGEEEEGEGKGEEEGEEGEGEGEEEEGEGE 940



 Score = 47.0 bits (110), Expect = 3e-06
 Identities = 28/80 (35%), Positives = 43/80 (53%)

Query: 18  KEKKEKVEEKASRKERKKEVVEEEENGAEEEEEETAEDGEEEDEGEEEDEEEEEEDDEGP 77
           +E + + EE+    + ++E  E E  G EEE E   EDGE E E EE + E EEE+ EG 
Sbjct: 906 EEGEGEGEEEEGEGKGEEEGEEGEGEGEEEEGEGEGEDGEGEGEEEEGEWEGEEEEGEGE 965

Query: 78  ALKRAAEEEDEADPKRQKTE 97
             +    E +E + + ++ E
Sbjct: 966 GEEEGEGEGEEGEGEGEEEE 985



 Score = 46.6 bits (109), Expect = 4e-06
 Identities = 35/102 (34%), Positives = 50/102 (49%), Gaps = 7/102 (6%)

Query: 3   EKSVEAAAELSAKDLKEKKEKVEEKASRKERKKEVVEEEENG----AEEEEEETAEDGEE 58
           E+  E   E    + +E + + EE   + E + E  E EE G     E EEEE   +GEE
Sbjct: 830 EEEGEGEEEEGEGEEEEGEGEEEEGEGKGEEEGEEGEGEEEGEEGEGEGEEEEGEGEGEE 889

Query: 59  EDEGEEEDEE---EEEEDDEGPALKRAAEEEDEADPKRQKTE 97
           E EGE E+EE   E EE+ EG   +   E + E + +  + E
Sbjct: 890 EGEGEGEEEEGEGEGEEEGEGEGEEEEGEGKGEEEGEEGEGE 931



 Score = 46.6 bits (109), Expect = 4e-06
 Identities = 34/97 (35%), Positives = 44/97 (45%), Gaps = 2/97 (2%)

Query: 3   EKSVEAAAELSAKDLKEKKEKVEEKASRKERKKEVVEEEENGAEEEEEETAEDGEEEDEG 62
           E+  E   E   +   E++E   E     E + E  E E  G EE EE   E  EEE EG
Sbjct: 880 EEEGEGEGEEEGEGEGEEEEGEGEGEEEGEGEGEEEEGEGKGEEEGEEGEGEGEEEEGEG 939

Query: 63  EEEDEEEEEEDDEGPALKRAAEEEDEADPKRQKTENG 99
           E ED E E E++EG       EEE E + + +    G
Sbjct: 940 EGEDGEGEGEEEEGE--WEGEEEEGEGEGEEEGEGEG 974



 Score = 45.1 bits (105), Expect = 1e-05
 Identities = 33/103 (32%), Positives = 47/103 (45%), Gaps = 6/103 (5%)

Query: 3   EKSVEAAAELSAKDLKEKKEKVEEKASRKERKKEVVEEEENGAEEEEEETAEDGEEEDEG 62
           E+  E   E   ++ + + E+ E +   +E  +   EEEE   E EEE   E  EEE EG
Sbjct: 860 EEGEEGEGEEEGEEGEGEGEEEEGEGEGEEEGEGEGEEEEGEGEGEEEGEGEGEEEEGEG 919

Query: 63  EEEDE------EEEEEDDEGPALKRAAEEEDEADPKRQKTENG 99
           + E+E      E EEE+ EG       E E+E      + E G
Sbjct: 920 KGEEEGEEGEGEGEEEEGEGEGEDGEGEGEEEEGEWEGEEEEG 962



 Score = 45.1 bits (105), Expect = 1e-05
 Identities = 34/109 (31%), Positives = 50/109 (45%), Gaps = 12/109 (11%)

Query: 3    EKSVEAAAELSAKDLKEKKEKVEEKASRKERKKEVVEEEENGAEEEEEETAEDGEEEDEG 62
            E   E   E   ++ + K E+  E+   +  ++E   E E+G  E EEE  E   EE+EG
Sbjct: 903  EGEEEGEGEGEEEEGEGKGEEEGEEGEGEGEEEEGEGEGEDGEGEGEEEEGEWEGEEEEG 962

Query: 63   EEEDEEE------------EEEDDEGPALKRAAEEEDEADPKRQKTENG 99
            E E EEE            EEE+ EG   +   EEE E + + ++   G
Sbjct: 963  EGEGEEEGEGEGEEGEGEGEEEEGEGEGEEEEGEEEGEEEGEGEEEGEG 1011



 Score = 45.1 bits (105), Expect = 1e-05
 Identities = 34/101 (33%), Positives = 52/101 (51%), Gaps = 8/101 (7%)

Query: 3    EKSVEAAAELSAKDLKEKKEKVEEKASRKERKKEVVEEEENG-AEEEEEETAEDGE---E 58
            E+  E   E   ++ + + E  E +   +E + E  EEE  G  EEE E   E+GE   E
Sbjct: 923  EEGEEGEGEGEEEEGEGEGEDGEGEGEEEEGEWEGEEEEGEGEGEEEGEGEGEEGEGEGE 982

Query: 59   EDEGEEEDEEEEEEDDEGPALKRAAEEEDEADPKRQKTENG 99
            E+EGE E EEEE E++     +   E E+E + + ++ E G
Sbjct: 983  EEEGEGEGEEEEGEEEG----EEEGEGEEEGEGEGEEEEEG 1019



 Score = 43.9 bits (102), Expect = 3e-05
 Identities = 35/109 (32%), Positives = 56/109 (51%), Gaps = 13/109 (11%)

Query: 2   SEKSVEAAAELSAKDLKEKKEKVEEKASRKERKKEVVEEEENGAEEEE------EETA-- 53
           +++  E   E   +  +E+ ++ EE+    E K+E   EE  G  E+E      EE A  
Sbjct: 724 NQEMEEGGEEEHGEGEEEEGDREEEEEKEGEGKEEGEGEEVEGEREKEEGERKKEERAGK 783

Query: 54  -EDGEEE-DEGEEEDEEEE---EEDDEGPALKRAAEEEDEADPKRQKTE 97
            E GEEE D+GE E+EE E   EE +EG  ++    EE + + + ++ E
Sbjct: 784 EEKGEEEGDQGEGEEEETEGRGEEKEEGGEVEGGEVEEGKGEREEEEEE 832



 Score = 43.9 bits (102), Expect = 3e-05
 Identities = 30/95 (31%), Positives = 45/95 (47%)

Query: 3   EKSVEAAAELSAKDLKEKKEKVEEKASRKERKKEVVEEEENGAEEEEEETAEDGEEEDEG 62
           E+  E   E   ++ + + E+  E    +E  +   EEE  G  EEEE   +  EE +EG
Sbjct: 869 EEGEEGEGEGEEEEGEGEGEEEGEGEGEEEEGEGEGEEEGEGEGEEEEGEGKGEEEGEEG 928

Query: 63  EEEDEEEEEEDDEGPALKRAAEEEDEADPKRQKTE 97
           E E EEEE E +         EEE E + + ++ E
Sbjct: 929 EGEGEEEEGEGEGEDGEGEGEEEEGEWEGEEEEGE 963



 Score = 42.7 bits (99), Expect = 6e-05
 Identities = 24/71 (33%), Positives = 42/71 (59%), Gaps = 2/71 (2%)

Query: 3    EKSVEAAAELSAKDLKEKKEKVEEKASRKERKKEVVEEEENGAEEEEEETAEDGEEEDEG 62
            E+  E   E+  ++ + + E+ E +   +ER+KE   EE     EEEEE  E+G+ ++ G
Sbjct: 1016 EEEGEVEGEVEGEEGEGEGEEEEGEEEGEEREKEGEGEENRRNREEEEE--EEGKYQETG 1073

Query: 63   EEEDEEEEEED 73
            EEE+E ++ E+
Sbjct: 1074 EEENERQDGEE 1084



 Score = 42.4 bits (98), Expect = 8e-05
 Identities = 26/79 (32%), Positives = 41/79 (51%), Gaps = 5/79 (6%)

Query: 16  DLKEKKEKVEEKASRKERKKEVVEEEENGAEEEEEETAEDGEEEDEGEEEDEEEEEEDDE 75
           +++   E  +E A ++E KK   EE+E    E+  +   + E E+ GEEE  E EEE+ +
Sbjct: 685 EMERPGEGEKELAEKEEWKKRDGEEQEQKEREQGHQKERNQEMEEGGEEEHGEGEEEEGD 744

Query: 76  GPALKRAAEEEDEADPKRQ 94
                R  EEE E + K +
Sbjct: 745 -----REEEEEKEGEGKEE 758



 Score = 41.6 bits (96), Expect = 1e-04
 Identities = 33/102 (32%), Positives = 50/102 (49%), Gaps = 9/102 (8%)

Query: 1   MSEKSVEAAAELSAKDLKEKKEKVE-------EKASRKERKKEVVEEEENGAEEEEEETA 53
           + E+ VEA  E + K    +KEK E       +KA   E K + V E E+G E   + T 
Sbjct: 601 IEEQEVEANEE-NVKVHGGRKEKTEILSDDLTDKAEVSEGKAKSVGEAEDGPEGRGDGTC 659

Query: 54  EDGEEEDEGEEEDEEEEEEDDEGPA-LKRAAEEEDEADPKRQ 94
           E+G    E  +++E E+ E D+G   ++R  E E E   K +
Sbjct: 660 EEGSSGAEHWQDEEREKGEKDKGRGEMERPGEGEKELAEKEE 701



 Score = 40.8 bits (94), Expect = 2e-04
 Identities = 28/91 (30%), Positives = 44/91 (48%)

Query: 7   EAAAELSAKDLKEKKEKVEEKASRKERKKEVVEEEENGAEEEEEETAEDGEEEDEGEEED 66
           E   E   ++ + + E  EE     E ++   + EE G E E E   E+GE E E  E +
Sbjct: 888 EEEGEGEGEEEEGEGEGEEEGEGEGEEEEGEGKGEEEGEEGEGEGEEEEGEGEGEDGEGE 947

Query: 67  EEEEEEDDEGPALKRAAEEEDEADPKRQKTE 97
            EEEE + EG   +   E E+E + + ++ E
Sbjct: 948 GEEEEGEWEGEEEEGEGEGEEEGEGEGEEGE 978



 Score = 39.7 bits (91), Expect = 5e-04
 Identities = 22/75 (29%), Positives = 37/75 (49%)

Query: 22   EKVEEKASRKERKKEVVEEEENGAEEEEEETAEDGEEEDEGEEEDEEEEEEDDEGPALKR 81
            E+ E +   +E ++E  E E+ G  EE     E+ EEE+   +E  EEE E  +G   K+
Sbjct: 1028 EEGEGEGEEEEGEEEGEEREKEGEGEENRRNREEEEEEEGKYQETGEEENERQDGEEYKK 1087

Query: 82   AAEEEDEADPKRQKT 96
             ++ +      + KT
Sbjct: 1088 VSKIKGSVKYGKHKT 1102



 Score = 35.4 bits (80), Expect = 0.010
 Identities = 30/107 (28%), Positives = 48/107 (44%), Gaps = 18/107 (16%)

Query: 11  ELSAKDLKEKKEKVEEKASR--------KERKKEVVEEEENGAEEEEEETAEDGEEED-- 60
           E+ + DL +K E  E KA          + R     EE  +GAE  ++E  E GE++   
Sbjct: 624 EILSDDLTDKAEVSEGKAKSVGEAEDGPEGRGDGTCEEGSSGAEHWQDEEREKGEKDKGR 683

Query: 61  -------EGEEEDEEEEE-EDDEGPALKRAAEEEDEADPKRQKTENG 99
                  EGE+E  E+EE +  +G   ++   E+     + Q+ E G
Sbjct: 684 GEMERPGEGEKELAEKEEWKKRDGEEQEQKEREQGHQKERNQEMEEG 730



 Score = 34.3 bits (77), Expect = 0.022
 Identities = 27/84 (32%), Positives = 41/84 (48%), Gaps = 2/84 (2%)

Query: 19  EKKEKVEEKASRKERKKEVVEEEENGAEEEEEETAEDGEEEDEGEEEDEEEEEEDDEGPA 78
           E+ E  EEK   ++ K   +EE+E  A EE  +     +E+ E   +D  ++ E  EG A
Sbjct: 582 EEVEIPEEKEGAEDSKGNGIEEQEVEANEENVKVHGGRKEKTEILSDDLTDKAEVSEGKA 641

Query: 79  LKRAAEEEDEADPKRQKT-ENGAS 101
            K   E ED  + +   T E G+S
Sbjct: 642 -KSVGEAEDGPEGRGDGTCEEGSS 664



 Score = 33.9 bits (76), Expect = 0.028
 Identities = 23/84 (27%), Positives = 42/84 (50%), Gaps = 10/84 (11%)

Query: 25  EEKASRKERKKEVVEEEENGAEEEEEETAEDGEEEDEGEEEDEEEEE---------EDDE 75
           +E+  + E+ K   E E  G  E+E    E+ ++ D GEE++++E E         E +E
Sbjct: 671 DEEREKGEKDKGRGEMERPGEGEKELAEKEEWKKRD-GEEQEQKEREQGHQKERNQEMEE 729

Query: 76  GPALKRAAEEEDEADPKRQKTENG 99
           G   +    EE+E D + ++ + G
Sbjct: 730 GGEEEHGEGEEEEGDREEEEEKEG 753



 Score = 28.1 bits (61), Expect = 1.6
 Identities = 22/88 (25%), Positives = 41/88 (46%), Gaps = 7/88 (7%)

Query: 12  LSAKDLKEKKEKVEEKASRKERKKEVVEEEENGAEEEEEETAEDGEEEDEGEEEDEEEEE 71
           L+  D  ++ E++ E    K  K+ V +    G    +  T  +   ++E E  +E+E  
Sbjct: 538 LTENDDSDEYEEMSEMKEGKACKQHVSQ----GIFMTQPATTIEAFSDEEVEIPEEKEGA 593

Query: 72  EDDEGPALKRAAEEEDEADPKRQKTENG 99
           ED +G  ++   E+E EA+ +  K   G
Sbjct: 594 EDSKGNGIE---EQEVEANEENVKVHGG 618


>gi|239508778 PREDICTED: hypothetical protein, partial [Homo
           sapiens]
          Length = 123

 Score = 62.0 bits (149), Expect = 1e-10
 Identities = 37/95 (38%), Positives = 56/95 (58%), Gaps = 8/95 (8%)

Query: 3   EKSVEAAAELSAKDLKEKKEKVEEKASRKERKKEVVEEEENGAEEEEEETAEDGEEEDEG 62
           EK  E   +   K+ +++KEK EE+  RK ++K+  EEEE    EEEEE     EEE+E 
Sbjct: 35  EKRKEKEKKKKTKETEKRKEKEEEEKKRKRKRKKKKEEEER---EEEEE-----EEEEEK 86

Query: 63  EEEDEEEEEEDDEGPALKRAAEEEDEADPKRQKTE 97
           EEE++EE     +    +R  EEE++   +R+KT+
Sbjct: 87  EEEEKEEGRRRKKKKKRRRKEEEEEKKKKRRRKTK 121



 Score = 49.7 bits (117), Expect = 5e-07
 Identities = 27/86 (31%), Positives = 52/86 (60%), Gaps = 5/86 (5%)

Query: 15 KDLKEKKEKVEEKASRKERKKEVVEEEENGAEEEEEETAEDGEEEDEG-----EEEDEEE 69
          ++ +E +E+ E++  RKE++KE  +E+E   + +E E  ++ EEE++      +++ EEE
Sbjct: 14 EETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEKKRKRKRKKKKEEE 73

Query: 70 EEEDDEGPALKRAAEEEDEADPKRQK 95
          E E++E    +   EEE E   +R+K
Sbjct: 74 EREEEEEEEEEEKEEEEKEEGRRRKK 99



 Score = 44.3 bits (103), Expect = 2e-05
 Identities = 23/66 (34%), Positives = 42/66 (63%), Gaps = 2/66 (3%)

Query: 30 RKERKKEVVEEEENGAEEEEEETAEDGEEEDEGEEEDEEEEEEDDEGPALKRAAEEEDEA 89
          +K++KKE  E EE   EE EEE  ++G+ +++ +E+ +E+E++       KR  +EE+E 
Sbjct: 3  KKKKKKETEETEET--EETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEK 60

Query: 90 DPKRQK 95
            KR++
Sbjct: 61 KRKRKR 66



 Score = 42.4 bits (98), Expect = 8e-05
 Identities = 26/71 (36%), Positives = 40/71 (56%), Gaps = 5/71 (7%)

Query: 2   SEKSVEAAAELSAKDLKEKKEKVEEKASRKERKKEVVEEEENGAEEEEEETAEDGEEEDE 61
           +EK  E   E   +  K KK+K EE     ER++E  EEEE   EEE+EE     +++  
Sbjct: 49  TEKRKEKEEEEKKRKRKRKKKKEEE-----EREEEEEEEEEEKEEEEKEEGRRRKKKKKR 103

Query: 62  GEEEDEEEEEE 72
             +E+EEE+++
Sbjct: 104 RRKEEEEEKKK 114



 Score = 41.6 bits (96), Expect = 1e-04
 Identities = 21/83 (25%), Positives = 46/83 (55%)

Query: 15 KDLKEKKEKVEEKASRKERKKEVVEEEENGAEEEEEETAEDGEEEDEGEEEDEEEEEEDD 74
          K  KE +E  E + + +E +KE   +E+   + +E+E  +  +E ++ +E++EEE++   
Sbjct: 5  KKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEKKRKR 64

Query: 75 EGPALKRAAEEEDEADPKRQKTE 97
          +    K   E E+E + + ++ E
Sbjct: 65 KRKKKKEEEEREEEEEEEEEEKE 87


>gi|94536805 splicing factor YT521-B isoform 2 [Homo sapiens]
          Length = 709

 Score = 60.5 bits (145), Expect = 3e-10
 Identities = 32/73 (43%), Positives = 47/73 (64%), Gaps = 4/73 (5%)

Query: 25  EEKASRKERKKEVVEEEENGAEEEEEETAEDGEEEDEGEEEDEEEEEEDDEGPALKRAAE 84
           +E+ +  E ++E VEE+    EE EE+  ED E +++GEEE+EEEEEE++E    +   E
Sbjct: 192 DEQGNNTENEEEGVEEDVEEDEEVEEDAEEDEEVDEDGEEEEEEEEEEEEE----EEEEE 247

Query: 85  EEDEADPKRQKTE 97
           EE E D + QK E
Sbjct: 248 EEYEQDERDQKEE 260



 Score = 55.1 bits (131), Expect = 1e-08
 Identities = 29/90 (32%), Positives = 49/90 (54%)

Query: 6   VEAAAELSAKDLKEKKEKVEEKASRKERKKEVVEEEENGAEEEEEETAEDGEEEDEGEEE 65
           V+  A  S++  KE+    E  +  +       +E+ N  E EEE   ED EE++E EE+
Sbjct: 159 VDRRASRSSQSSKEEVNSEEYGSDHETGSSGSSDEQGNNTENEEEGVEEDVEEDEEVEED 218

Query: 66  DEEEEEEDDEGPALKRAAEEEDEADPKRQK 95
            EE+EE D++G   +   EEE+E + + ++
Sbjct: 219 AEEDEEVDEDGEEEEEEEEEEEEEEEEEEE 248



 Score = 54.7 bits (130), Expect = 2e-08
 Identities = 34/85 (40%), Positives = 55/85 (64%), Gaps = 4/85 (4%)

Query: 22  EKVEEKASRKERKKEVVEEEENGAE--EEEEETAEDGEEEDEGEEEDEE-EEEEDDEGPA 78
           E+     + +E  +E VEE+E   E  EE+EE  EDGEEE+E EEE+EE EEEE++E   
Sbjct: 193 EQGNNTENEEEGVEEDVEEDEEVEEDAEEDEEVDEDGEEEEEEEEEEEEEEEEEEEEYEQ 252

Query: 79  LKRAAEEE-DEADPKRQKTENGASA 102
            +R  +EE ++ D + + +++G+ +
Sbjct: 253 DERDQKEEGNDYDTRSEASDSGSES 277



 Score = 53.1 bits (126), Expect = 5e-08
 Identities = 29/89 (32%), Positives = 48/89 (53%), Gaps = 4/89 (4%)

Query: 3   EKSVEAAAELSAKDLKEKKEKVEEKASRKERKKEVVEEEE----NGAEEEEEETAEDGEE 58
           E     +++    + + ++E VEE     E  +E  EE+E    +G EEEEEE  E+ EE
Sbjct: 184 ETGSSGSSDEQGNNTENEEEGVEEDVEEDEEVEEDAEEDEEVDEDGEEEEEEEEEEEEEE 243

Query: 59  EDEGEEEDEEEEEEDDEGPALKRAAEEED 87
           E+E EE +++E ++ +EG      +E  D
Sbjct: 244 EEEEEEYEQDERDQKEEGNDYDTRSEASD 272



 Score = 52.4 bits (124), Expect = 8e-08
 Identities = 33/100 (33%), Positives = 51/100 (51%), Gaps = 4/100 (4%)

Query: 2   SEKSVEAAAELSAKDLKEKKEKVEEKASRKERKKEVVEEEENGAEE--EEEETAEDGEEE 59
           S  S  +  E+++++     E     +S ++      E EE G EE  EE+E  E+  EE
Sbjct: 164 SRSSQSSKEEVNSEEYGSDHETGSSGSSDEQGNN--TENEEEGVEEDVEEDEEVEEDAEE 221

Query: 60  DEGEEEDEEEEEEDDEGPALKRAAEEEDEADPKRQKTENG 99
           DE  +ED EEEEE++E    +   EEE+    +R + E G
Sbjct: 222 DEEVDEDGEEEEEEEEEEEEEEEEEEEEYEQDERDQKEEG 261



 Score = 50.4 bits (119), Expect = 3e-07
 Identities = 28/71 (39%), Positives = 43/71 (60%), Gaps = 3/71 (4%)

Query: 19  EKKEKVEEKASRKERKKEVVEEEENGAEEEEEETAEDGEEEDEGEEEDEEEEEEDDEGPA 78
           E+ E+VEE A   E   E  EEEE   EEEEEE  E+ EEE+E E+++ +++EE ++   
Sbjct: 210 EEDEEVEEDAEEDEEVDEDGEEEE---EEEEEEEEEEEEEEEEYEQDERDQKEEGNDYDT 266

Query: 79  LKRAAEEEDEA 89
              A++   E+
Sbjct: 267 RSEASDSGSES 277



 Score = 46.2 bits (108), Expect = 6e-06
 Identities = 30/82 (36%), Positives = 45/82 (54%), Gaps = 13/82 (15%)

Query: 23  KVEEKASRKERK-KEVVEEEENGAEEE------EEETAEDGEEEDEGEEEDEEEEEEDDE 75
           +V+ +ASR  +  KE V  EE G++ E       +E   + E E+EG EED EE+EE +E
Sbjct: 158 EVDRRASRSSQSSKEEVNSEEYGSDHETGSSGSSDEQGNNTENEEEGVEEDVEEDEEVEE 217

Query: 76  GPALKRAAEEEDEADPKRQKTE 97
                  AEE++E D   ++ E
Sbjct: 218 D------AEEDEEVDEDGEEEE 233



 Score = 40.8 bits (94), Expect = 2e-04
 Identities = 26/95 (27%), Positives = 46/95 (48%), Gaps = 2/95 (2%)

Query: 3   EKSVEAAAELS--AKDLKEKKEKVEEKASRKERKKEVVEEEENGAEEEEEETAEDGEEED 60
           E+ VE   E+   A++ +E  E  EE+   +E ++E  EEEE   E++E +  E+G + D
Sbjct: 206 EEDVEEDEEVEEDAEEDEEVDEDGEEEEEEEEEEEEEEEEEEEEYEQDERDQKEEGNDYD 265

Query: 61  EGEEEDEEEEEEDDEGPALKRAAEEEDEADPKRQK 95
              E  +   E         R+    D +D K+++
Sbjct: 266 TRSEASDSGSESVSFTDGSVRSGSGTDGSDEKKKE 300


>gi|72534750 splicing factor YT521-B isoform 1 [Homo sapiens]
          Length = 727

 Score = 60.5 bits (145), Expect = 3e-10
 Identities = 32/73 (43%), Positives = 47/73 (64%), Gaps = 4/73 (5%)

Query: 25  EEKASRKERKKEVVEEEENGAEEEEEETAEDGEEEDEGEEEDEEEEEEDDEGPALKRAAE 84
           +E+ +  E ++E VEE+    EE EE+  ED E +++GEEE+EEEEEE++E    +   E
Sbjct: 192 DEQGNNTENEEEGVEEDVEEDEEVEEDAEEDEEVDEDGEEEEEEEEEEEEE----EEEEE 247

Query: 85  EEDEADPKRQKTE 97
           EE E D + QK E
Sbjct: 248 EEYEQDERDQKEE 260



 Score = 55.1 bits (131), Expect = 1e-08
 Identities = 29/90 (32%), Positives = 49/90 (54%)

Query: 6   VEAAAELSAKDLKEKKEKVEEKASRKERKKEVVEEEENGAEEEEEETAEDGEEEDEGEEE 65
           V+  A  S++  KE+    E  +  +       +E+ N  E EEE   ED EE++E EE+
Sbjct: 159 VDRRASRSSQSSKEEVNSEEYGSDHETGSSGSSDEQGNNTENEEEGVEEDVEEDEEVEED 218

Query: 66  DEEEEEEDDEGPALKRAAEEEDEADPKRQK 95
            EE+EE D++G   +   EEE+E + + ++
Sbjct: 219 AEEDEEVDEDGEEEEEEEEEEEEEEEEEEE 248



 Score = 54.7 bits (130), Expect = 2e-08
 Identities = 34/85 (40%), Positives = 55/85 (64%), Gaps = 4/85 (4%)

Query: 22  EKVEEKASRKERKKEVVEEEENGAE--EEEEETAEDGEEEDEGEEEDEE-EEEEDDEGPA 78
           E+     + +E  +E VEE+E   E  EE+EE  EDGEEE+E EEE+EE EEEE++E   
Sbjct: 193 EQGNNTENEEEGVEEDVEEDEEVEEDAEEDEEVDEDGEEEEEEEEEEEEEEEEEEEEYEQ 252

Query: 79  LKRAAEEE-DEADPKRQKTENGASA 102
            +R  +EE ++ D + + +++G+ +
Sbjct: 253 DERDQKEEGNDYDTRSEASDSGSES 277



 Score = 53.1 bits (126), Expect = 5e-08
 Identities = 29/89 (32%), Positives = 48/89 (53%), Gaps = 4/89 (4%)

Query: 3   EKSVEAAAELSAKDLKEKKEKVEEKASRKERKKEVVEEEE----NGAEEEEEETAEDGEE 58
           E     +++    + + ++E VEE     E  +E  EE+E    +G EEEEEE  E+ EE
Sbjct: 184 ETGSSGSSDEQGNNTENEEEGVEEDVEEDEEVEEDAEEDEEVDEDGEEEEEEEEEEEEEE 243

Query: 59  EDEGEEEDEEEEEEDDEGPALKRAAEEED 87
           E+E EE +++E ++ +EG      +E  D
Sbjct: 244 EEEEEEYEQDERDQKEEGNDYDTRSEASD 272



 Score = 52.4 bits (124), Expect = 8e-08
 Identities = 33/100 (33%), Positives = 51/100 (51%), Gaps = 4/100 (4%)

Query: 2   SEKSVEAAAELSAKDLKEKKEKVEEKASRKERKKEVVEEEENGAEE--EEEETAEDGEEE 59
           S  S  +  E+++++     E     +S ++      E EE G EE  EE+E  E+  EE
Sbjct: 164 SRSSQSSKEEVNSEEYGSDHETGSSGSSDEQGNN--TENEEEGVEEDVEEDEEVEEDAEE 221

Query: 60  DEGEEEDEEEEEEDDEGPALKRAAEEEDEADPKRQKTENG 99
           DE  +ED EEEEE++E    +   EEE+    +R + E G
Sbjct: 222 DEEVDEDGEEEEEEEEEEEEEEEEEEEEYEQDERDQKEEG 261



 Score = 50.4 bits (119), Expect = 3e-07
 Identities = 28/71 (39%), Positives = 43/71 (60%), Gaps = 3/71 (4%)

Query: 19  EKKEKVEEKASRKERKKEVVEEEENGAEEEEEETAEDGEEEDEGEEEDEEEEEEDDEGPA 78
           E+ E+VEE A   E   E  EEEE   EEEEEE  E+ EEE+E E+++ +++EE ++   
Sbjct: 210 EEDEEVEEDAEEDEEVDEDGEEEE---EEEEEEEEEEEEEEEEYEQDERDQKEEGNDYDT 266

Query: 79  LKRAAEEEDEA 89
              A++   E+
Sbjct: 267 RSEASDSGSES 277



 Score = 46.2 bits (108), Expect = 6e-06
 Identities = 30/82 (36%), Positives = 45/82 (54%), Gaps = 13/82 (15%)

Query: 23  KVEEKASRKERK-KEVVEEEENGAEEE------EEETAEDGEEEDEGEEEDEEEEEEDDE 75
           +V+ +ASR  +  KE V  EE G++ E       +E   + E E+EG EED EE+EE +E
Sbjct: 158 EVDRRASRSSQSSKEEVNSEEYGSDHETGSSGSSDEQGNNTENEEEGVEEDVEEDEEVEE 217

Query: 76  GPALKRAAEEEDEADPKRQKTE 97
                  AEE++E D   ++ E
Sbjct: 218 D------AEEDEEVDEDGEEEE 233



 Score = 40.8 bits (94), Expect = 2e-04
 Identities = 26/95 (27%), Positives = 46/95 (48%), Gaps = 2/95 (2%)

Query: 3   EKSVEAAAELS--AKDLKEKKEKVEEKASRKERKKEVVEEEENGAEEEEEETAEDGEEED 60
           E+ VE   E+   A++ +E  E  EE+   +E ++E  EEEE   E++E +  E+G + D
Sbjct: 206 EEDVEEDEEVEEDAEEDEEVDEDGEEEEEEEEEEEEEEEEEEEEYEQDERDQKEEGNDYD 265

Query: 61  EGEEEDEEEEEEDDEGPALKRAAEEEDEADPKRQK 95
              E  +   E         R+    D +D K+++
Sbjct: 266 TRSEASDSGSESVSFTDGSVRSGSGTDGSDEKKKE 300


>gi|155030232 proline, glutamic acid and leucine rich protein 1
           [Homo sapiens]
          Length = 1130

 Score = 59.7 bits (143), Expect = 5e-10
 Identities = 32/88 (36%), Positives = 56/88 (63%), Gaps = 2/88 (2%)

Query: 11  ELSAKDLKEKKEKVEEKASRKERKKEVVEEEENGAEEEEEETAEDGEEEDEGEEEDEEEE 70
           +L+  ++    E+ EE+   +E ++E  EEEE+  EEEE+E  E+  EE+E EEE+ EEE
Sbjct: 877 DLTVININSSDEEEEEEEEEEEEEEEEEEEEEDFEEEEEDE--EEYFEEEEEEEEEFEEE 934

Query: 71  EEDDEGPALKRAAEEEDEADPKRQKTEN 98
            E++EG   +   EE++E + + ++ E+
Sbjct: 935 FEEEEGELEEEEEEEDEEEEEELEEVED 962



 Score = 56.2 bits (134), Expect = 5e-09
 Identities = 39/91 (42%), Positives = 52/91 (57%), Gaps = 4/91 (4%)

Query: 3   EKSVEAAAELSAKDLKEKKEKVEEKASRKERKKEVVEEEENGAEEEEEETAEDGEEEDEG 62
           E+  E   E   ++ +E++E  EE+   +E   E  EEEE   EEE EE  E+GE E+E 
Sbjct: 889 EEEEEEEEEEEEEEEEEEEEDFEEEEEDEEEYFEEEEEEEEEFEEEFEE--EEGELEEEE 946

Query: 63  EEEDEEEEEEDDEGPALK--RAAEEEDEADP 91
           EEEDEEEEEE +E   L+   A  E +E  P
Sbjct: 947 EEEDEEEEEELEEVEDLEFGTAGGEVEEGAP 977



 Score = 52.0 bits (123), Expect = 1e-07
 Identities = 33/89 (37%), Positives = 49/89 (55%)

Query: 3   EKSVEAAAELSAKDLKEKKEKVEEKASRKERKKEVVEEEENGAEEEEEETAEDGEEEDEG 62
           E+  E   E   ++ +E+++  EE+   +E  +E  EEEE   EE EEE  E  EEE+E 
Sbjct: 890 EEEEEEEEEEEEEEEEEEEDFEEEEEDEEEYFEEEEEEEEEFEEEFEEEEGELEEEEEEE 949

Query: 63  EEEDEEEEEEDDEGPALKRAAEEEDEADP 91
           +EE+EEE EE ++        E E+ A P
Sbjct: 950 DEEEEEELEEVEDLEFGTAGGEVEEGAPP 978



 Score = 51.2 bits (121), Expect = 2e-07
 Identities = 29/74 (39%), Positives = 44/74 (59%)

Query: 2   SEKSVEAAAELSAKDLKEKKEKVEEKASRKERKKEVVEEEENGAEEEEEETAEDGEEEDE 61
           S    E   E   ++ +E++E+ E+    +E ++E  EEEE   EE EEE  E+  E +E
Sbjct: 885 SSDEEEEEEEEEEEEEEEEEEEEEDFEEEEEDEEEYFEEEEEEEEEFEEEFEEEEGELEE 944

Query: 62  GEEEDEEEEEEDDE 75
            EEE++EEEEE+ E
Sbjct: 945 EEEEEDEEEEEELE 958



 Score = 37.7 bits (86), Expect = 0.002
 Identities = 24/62 (38%), Positives = 33/62 (53%)

Query: 18  KEKKEKVEEKASRKERKKEVVEEEENGAEEEEEETAEDGEEEDEGEEEDEEEEEEDDEGP 77
           +E++E+ EE+   +E + E  EEEE+  EEEE E  ED E    G E +E         P
Sbjct: 925 EEEEEEFEEEFEEEEGELEEEEEEEDEEEEEELEEVEDLEFGTAGGEVEEGAPPPPTLPP 984

Query: 78  AL 79
           AL
Sbjct: 985 AL 986



 Score = 36.2 bits (82), Expect = 0.006
 Identities = 32/101 (31%), Positives = 42/101 (41%), Gaps = 9/101 (8%)

Query: 3   EKSVEAAAELSAKDLKEKKEKVEEKASRKERKKEVVEEE---------ENGAEEEEEETA 53
           E+  E   E   +D +E++E  EE    +E ++E  EEE         E   EE+EEE  
Sbjct: 896 EEEEEEEEEEEEEDFEEEEEDEEEYFEEEEEEEEEFEEEFEEEEGELEEEEEEEDEEEEE 955

Query: 54  EDGEEEDEGEEEDEEEEEEDDEGPALKRAAEEEDEADPKRQ 94
           E  E ED        E EE    P     A    E+ PK Q
Sbjct: 956 ELEEVEDLEFGTAGGEVEEGAPPPPTLPPALPPPESPPKVQ 996



 Score = 34.7 bits (78), Expect = 0.017
 Identities = 18/53 (33%), Positives = 30/53 (56%)

Query: 45  AEEEEEETAEDGEEEDEGEEEDEEEEEEDDEGPALKRAAEEEDEADPKRQKTE 97
           A EE+         ++E EEE+EEEEEE++E    +   EEE++ +   ++ E
Sbjct: 873 ALEEDLTVININSSDEEEEEEEEEEEEEEEEEEEEEDFEEEEEDEEEYFEEEE 925



 Score = 33.5 bits (75), Expect = 0.037
 Identities = 24/88 (27%), Positives = 41/88 (46%), Gaps = 2/88 (2%)

Query: 3    EKSVEAAAELSAKDLKEKKE--KVEEKASRKERKKEVVEEEENGAEEEEEETAEDGEEED 60
            E+  + A  L+ + L  + E  +  E  +     +E+VEEE +      EE  EDG ++ 
Sbjct: 1017 ERGADTAPTLAPEALPSQGEVEREGESPAAGPPPQELVEEEPSAPPTLLEEETEDGSDKV 1076

Query: 61   EGEEEDEEEEEEDDEGPALKRAAEEEDE 88
            +   E   EEE + E  A     +E+D+
Sbjct: 1077 QPPPETPAEEEMETETEAEALQEKEQDD 1104



 Score = 30.4 bits (67), Expect = 0.31
 Identities = 22/61 (36%), Positives = 32/61 (52%), Gaps = 4/61 (6%)

Query: 21   KEKVEEKASRKERKKEVVEEEENGAEEEEEETAEDGEEEDEGEEEDE--EEEEEDDEGPA 78
            +E VEE+ S      E  EE E+G+++ +       EEE E E E E  +E+E+DD    
Sbjct: 1051 QELVEEEPSAPPTLLE--EETEDGSDKVQPPPETPAEEEMETETEAEALQEKEQDDTAAM 1108

Query: 79   L 79
            L
Sbjct: 1109 L 1109



 Score = 27.7 bits (60), Expect = 2.0
 Identities = 22/78 (28%), Positives = 30/78 (38%), Gaps = 1/78 (1%)

Query: 23   KVEEKASRKERKKEVVEEEENGAEEEEEETAEDGEEEDEGEEEDEEEEEEDDEGPALKRA 82
            +VEE  + +ER  +        A   + E   +GE    G    E  EEE    P L   
Sbjct: 1008 EVEEPGTEEERGADTAPTLAPEALPSQGEVEREGESPAAGPPPQELVEEEPSAPPTLLE- 1066

Query: 83   AEEEDEADPKRQKTENGA 100
             E ED +D  +   E  A
Sbjct: 1067 EETEDGSDKVQPPPETPA 1084


>gi|239745093 PREDICTED: hypothetical protein XP_002343359 [Homo
           sapiens]
          Length = 142

 Score = 58.9 bits (141), Expect = 8e-10
 Identities = 34/84 (40%), Positives = 51/84 (60%), Gaps = 3/84 (3%)

Query: 10  AELSAKDLKEKKEKVEEKASRKERKKEVVEEEENGAEEEEEETAEDGEEEDEGEEEDEEE 69
           A  SA+  + ++EK  E+  R+E+++E  E+   G   E+EE  E+ EEE+E EEE+EEE
Sbjct: 58  AGTSARKSQRREEKRREEKRREEKRRE--EKRREGKRREKEEEKEEEEEEEE-EEEEEEE 114

Query: 70  EEEDDEGPALKRAAEEEDEADPKR 93
           EEE++E        E E E + KR
Sbjct: 115 EEEEEEVSFSLATRERETETEEKR 138



 Score = 48.5 bits (114), Expect = 1e-06
 Identities = 27/76 (35%), Positives = 44/76 (57%), Gaps = 8/76 (10%)

Query: 8   AAAELSAKDLKEKKEKVEEKASRKERKKEVVEEEENGAEEEEEETAEDGEEEDEGEEEDE 67
           +A +   ++ K ++EK  E+  R+E+++E    E+   +EEEEE  E+ EEE+E EEE+E
Sbjct: 61  SARKSQRREEKRREEKRREEKRREEKRREGKRREKEEEKEEEEEEEEEEEEEEEEEEEEE 120

Query: 68  --------EEEEEDDE 75
                   E E E +E
Sbjct: 121 VSFSLATRERETETEE 136



 Score = 38.1 bits (87), Expect = 0.002
 Identities = 20/78 (25%), Positives = 36/78 (46%)

Query: 13  SAKDLKEKKEKVEEKASRKERKKEVVEEEENGAEEEEEETAEDGEEEDEGEEEDEEEEEE 72
           S   +KE+   +    +    +K    EE+   E+  EE   + +  +    E EEE+EE
Sbjct: 42  STSSVKEEPPTLRHSMAGTSARKSQRREEKRREEKRREEKRREEKRREGKRREKEEEKEE 101

Query: 73  DDEGPALKRAAEEEDEAD 90
           ++E    +   EEE+E +
Sbjct: 102 EEEEEEEEEEEEEEEEEE 119



 Score = 30.4 bits (67), Expect = 0.31
 Identities = 19/70 (27%), Positives = 35/70 (50%), Gaps = 17/70 (24%)

Query: 28  ASRKERKKEVVEEEENGAEEEEEETAEDGEEEDEGEEEDEEEEEEDDEGPALKRAAEEED 87
           ++RK +++E    EE   EE+  E     E+  EG+  ++EEE+E            EE+
Sbjct: 61  SARKSQRREEKRREEKRREEKRRE-----EKRREGKRREKEEEKE------------EEE 103

Query: 88  EADPKRQKTE 97
           E + + ++ E
Sbjct: 104 EEEEEEEEEE 113


>gi|169210053 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 185

 Score = 57.8 bits (138), Expect = 2e-09
 Identities = 29/64 (45%), Positives = 43/64 (67%)

Query: 34  KKEVVEEEENGAEEEEEETAEDGEEEDEGEEEDEEEEEEDDEGPALKRAAEEEDEADPKR 93
           ++EV EEEE   EEE+EE  E+ EEE+E EEE EE+EEE+++        + E+E D + 
Sbjct: 120 EEEVEEEEEEVEEEEKEEEKEEDEEEEEKEEEKEEDEEEEEKEGKKMEEEKVEEEIDTEI 179

Query: 94  QKTE 97
           Q+T+
Sbjct: 180 QRTQ 183



 Score = 49.7 bits (117), Expect = 5e-07
 Identities = 28/68 (41%), Positives = 45/68 (66%), Gaps = 1/68 (1%)

Query: 9   AAELSAKD-LKEKKEKVEEKASRKERKKEVVEEEENGAEEEEEETAEDGEEEDEGEEEDE 67
           A E SA+  L  ++E+VEE+    E +++  E+EE+  EEE+EE  E+ EEE+E E +  
Sbjct: 107 AEECSAQQGLPVEEEEVEEEEEEVEEEEKEEEKEEDEEEEEKEEEKEEDEEEEEKEGKKM 166

Query: 68  EEEEEDDE 75
           EEE+ ++E
Sbjct: 167 EEEKVEEE 174



 Score = 36.6 bits (83), Expect = 0.004
 Identities = 25/75 (33%), Positives = 41/75 (54%), Gaps = 14/75 (18%)

Query: 1   MSEKSVEAAAELSAKDLKEKKEKVEEKASRKERKKEVVEEEENGAEEEEEETAEDGEEED 60
           + E+ VE   E   ++ KE++++ +E+   KE +KE         E+EEEE     E+E 
Sbjct: 118 VEEEEVEEEEEEVEEEEKEEEKEEDEEEEEKEEEKE---------EDEEEE-----EKEG 163

Query: 61  EGEEEDEEEEEEDDE 75
           +  EE++ EEE D E
Sbjct: 164 KKMEEEKVEEEIDTE 178



 Score = 33.9 bits (76), Expect = 0.028
 Identities = 21/54 (38%), Positives = 33/54 (61%), Gaps = 10/54 (18%)

Query: 49  EEETAEDG-----EEEDEGEEEDEEEEEEDDEGPALKRAAEEEDEADPKRQKTE 97
           EE +A+ G     EE +E EEE EEEE+E++     K   EEE+E + ++++ E
Sbjct: 108 EECSAQQGLPVEEEEVEEEEEEVEEEEKEEE-----KEEDEEEEEKEEEKEEDE 156


>gi|221219020 NYD-SP11 protein [Homo sapiens]
          Length = 2873

 Score = 57.4 bits (137), Expect = 2e-09
 Identities = 37/101 (36%), Positives = 59/101 (58%), Gaps = 6/101 (5%)

Query: 3    EKSVEAAAELSAKDLKEKKEKVEEKASRKERKKEVVEEEENGAEEEEEETAEDGEEEDEG 62
            E+  E   E   ++ + +KE+ E+K  +KE+KKE V+E+E   EE+EE  +E+  E    
Sbjct: 2264 EEEEERKEEEEGEEKQVEKEEEEKKKKKKEKKKEEVQEKEEVFEEKEEIMSEEETESLSD 2323

Query: 63   EEEDEE----EEEEDDEGPALKRAAEEEDEADPKRQKTENG 99
            EEE+EE    EEE D E   LK+  E++ +   +R+K+  G
Sbjct: 2324 EEEEEESCSLEEEVDREKEILKK--EKQFKLQEQRRKSLRG 2362



 Score = 52.0 bits (123), Expect = 1e-07
 Identities = 26/77 (33%), Positives = 46/77 (59%)

Query: 19   EKKEKVEEKASRKERKKEVVEEEENGAEEEEEETAEDGEEEDEGEEEDEEEEEEDDEGPA 78
            ++ E  E  +   E   + +E++E+ + EEEEE  E+ E E+E   E+EEE +E++EG  
Sbjct: 2218 DEVESEEHFSEEMESLLDELEKQESLSSEEEEEREEEEEREEEEVREEEEERKEEEEGEE 2277

Query: 79   LKRAAEEEDEADPKRQK 95
             +   EEE++   K++K
Sbjct: 2278 KQVEKEEEEKKKKKKEK 2294



 Score = 51.2 bits (121), Expect = 2e-07
 Identities = 26/84 (30%), Positives = 50/84 (59%)

Query: 14   AKDLKEKKEKVEEKASRKERKKEVVEEEENGAEEEEEETAEDGEEEDEGEEEDEEEEEED 73
            +++++   +++E++ S    ++E  EEEE   EEE  E  E+ +EE+EGEE+  E+EEE+
Sbjct: 2227 SEEMESLLDELEKQESLSSEEEEEREEEEEREEEEVREEEEERKEEEEGEEKQVEKEEEE 2286

Query: 74   DEGPALKRAAEEEDEADPKRQKTE 97
             +    ++  EE  E +   ++ E
Sbjct: 2287 KKKKKKEKKKEEVQEKEEVFEEKE 2310



 Score = 48.9 bits (115), Expect = 9e-07
 Identities = 28/84 (33%), Positives = 46/84 (54%)

Query: 14   AKDLKEKKEKVEEKASRKERKKEVVEEEENGAEEEEEETAEDGEEEDEGEEEDEEEEEED 73
            AK   + KEK   +    E ++   EE E+  +E E++ +   EEE+E EEE+E EEEE 
Sbjct: 2203 AKRGDKPKEKFSSQVDEVESEEHFSEEMESLLDELEKQESLSSEEEEEREEEEEREEEEV 2262

Query: 74   DEGPALKRAAEEEDEADPKRQKTE 97
             E    ++  EE +E   ++++ E
Sbjct: 2263 REEEEERKEEEEGEEKQVEKEEEE 2286



 Score = 47.8 bits (112), Expect = 2e-06
 Identities = 25/81 (30%), Positives = 46/81 (56%)

Query: 15   KDLKEKKEKVEEKASRKERKKEVVEEEENGAEEEEEETAEDGEEEDEGEEEDEEEEEEDD 74
            + L ++ EK E  +S +E ++E  EE E     EEEE  ++ EE +E + E EEEE++  
Sbjct: 2231 ESLLDELEKQESLSSEEEEEREEEEEREEEEVREEEEERKEEEEGEEKQVEKEEEEKKKK 2290

Query: 75   EGPALKRAAEEEDEADPKRQK 95
            +    K   +E++E   ++++
Sbjct: 2291 KKEKKKEEVQEKEEVFEEKEE 2311



 Score = 46.6 bits (109), Expect = 4e-06
 Identities = 25/83 (30%), Positives = 44/83 (53%)

Query: 13   SAKDLKEKKEKVEEKASRKERKKEVVEEEENGAEEEEEETAEDGEEEDEGEEEDEEEEEE 72
            S +   E+ E + ++  ++E      EEE    EE EEE   + EEE + EEE EE++ E
Sbjct: 2222 SEEHFSEEMESLLDELEKQESLSSEEEEEREEEEEREEEEVREEEEERKEEEEGEEKQVE 2281

Query: 73   DDEGPALKRAAEEEDEADPKRQK 95
             +E    K+  E++ E   ++++
Sbjct: 2282 KEEEEKKKKKKEKKKEEVQEKEE 2304



 Score = 46.2 bits (108), Expect = 6e-06
 Identities = 29/95 (30%), Positives = 50/95 (52%), Gaps = 2/95 (2%)

Query: 4    KSVEAAAELSAKDLKEKKEKVEEKASRKERKKEVVEEEENGAEEEEEETAEDGEEEDEGE 63
            + +E+  +   K      E+ EE+   +ER++E V EEE   E +EEE  E+ + E E E
Sbjct: 2228 EEMESLLDELEKQESLSSEEEEEREEEEEREEEEVREEEE--ERKEEEEGEEKQVEKEEE 2285

Query: 64   EEDEEEEEEDDEGPALKRAAEEEDEADPKRQKTEN 98
            E+ ++++E+  E    K    EE E     ++TE+
Sbjct: 2286 EKKKKKKEKKKEEVQEKEEVFEEKEEIMSEEETES 2320



 Score = 43.9 bits (102), Expect = 3e-05
 Identities = 29/107 (27%), Positives = 58/107 (54%), Gaps = 12/107 (11%)

Query: 1    MSEKSVEAAAELSAKDLKEKKEKVEEKASRKERKKEVVE-EEENGAEEEEEETAEDGEEE 59
            +S +  E   E   ++ +E +E+ EE+   +E +++ VE EEE   ++++E+  E+ +E+
Sbjct: 2243 LSSEEEEEREEEEEREEEEVREEEEERKEEEEGEEKQVEKEEEEKKKKKKEKKKEEVQEK 2302

Query: 60   DEGEEEDEE-----------EEEEDDEGPALKRAAEEEDEADPKRQK 95
            +E  EE EE           +EEE++E  +L+   + E E   K ++
Sbjct: 2303 EEVFEEKEEIMSEEETESLSDEEEEEESCSLEEEVDREKEILKKEKQ 2349



 Score = 43.1 bits (100), Expect = 5e-05
 Identities = 23/96 (23%), Positives = 55/96 (57%)

Query: 6    VEAAAELSAKDLKEKKEKVEEKASRKERKKEVVEEEENGAEEEEEETAEDGEEEDEGEEE 65
            +E    LS+++ +E++E+ E +      ++E  +EEE G E++ E+  E+ +++ + +++
Sbjct: 2237 LEKQESLSSEEEEEREEEEEREEEEVREEEEERKEEEEGEEKQVEKEEEEKKKKKKEKKK 2296

Query: 66   DEEEEEEDDEGPALKRAAEEEDEADPKRQKTENGAS 101
            +E +E+E+      +  +EEE E+    ++ E   S
Sbjct: 2297 EEVQEKEEVFEEKEEIMSEEETESLSDEEEEEESCS 2332



 Score = 43.1 bits (100), Expect = 5e-05
 Identities = 31/91 (34%), Positives = 45/91 (49%), Gaps = 5/91 (5%)

Query: 3    EKSVEAAAELSAKDLKEKKEKVEEKASRKERKKEVVEEEENGAEEEEEETAEDG-----E 57
            EK    ++E   +  +E++ + EE    +E +KE  E EE   E+EEEE  +       E
Sbjct: 2238 EKQESLSSEEEEEREEEEEREEEEVREEEEERKEEEEGEEKQVEKEEEEKKKKKKEKKKE 2297

Query: 58   EEDEGEEEDEEEEEEDDEGPALKRAAEEEDE 88
            E  E EE  EE+EE   E      + EEE+E
Sbjct: 2298 EVQEKEEVFEEKEEIMSEEETESLSDEEEEE 2328



 Score = 40.0 bits (92), Expect = 4e-04
 Identities = 28/83 (33%), Positives = 43/83 (51%), Gaps = 7/83 (8%)

Query: 18   KEKKEKVEEKASRK-ERKKEVVEEEENGAEEEEEETAEDGEEEDEGEEEDEEEEEEDDEG 76
            K K+ K  +K   K   + + VE EE+ +EE E    E  ++E    EE+EE EEE++  
Sbjct: 2199 KRKEAKRGDKPKEKFSSQVDEVESEEHFSEEMESLLDELEKQESLSSEEEEEREEEEE-- 2256

Query: 77   PALKRAAEEEDEADPKRQKTENG 99
                R  EE  E + +R++ E G
Sbjct: 2257 ----REEEEVREEEEERKEEEEG 2275



 Score = 35.8 bits (81), Expect = 0.007
 Identities = 28/91 (30%), Positives = 46/91 (50%), Gaps = 10/91 (10%)

Query: 7    EAAAELSAKDLKEKKEKV---EEKASRKERK-----KEVVEEEENGAEEEEEETAEDGEE 58
            ++  ++   D  EK+ ++   E+K +RK+RK     + ++ +EE   EEE +   +  E 
Sbjct: 2115 QSKLDIKEWDFSEKRSELTKDEKKLARKQRKLANKMRRMINKEEKMTEEESKLARKHSEV 2174

Query: 59   EDEGEEEDEEEEEEDDEGPALKRAAEEEDEA 89
              + EEE   EEEE    P LKR   +  EA
Sbjct: 2175 ILDDEEEGGIEEEE--VIPFLKRRWRKRKEA 2203



 Score = 34.7 bits (78), Expect = 0.017
 Identities = 34/114 (29%), Positives = 56/114 (49%), Gaps = 21/114 (18%)

Query: 3    EKSVEAAAELSAKDLK-----EKKEKVEEKASRK-----------ERKKEVVEEEENGAE 46
            EK  + A +L+ K  K     EK  + EEK ++K            +K E + + E   +
Sbjct: 1649 EKLSQEAEKLAQKRKKLAKKWEKVAREEEKLAKKGGKLAEVKNILAQKVEELPQREQNLD 1708

Query: 47   EEEEETAEDGEEEDEGEEE--DEEEEEEDDEGPAL---KRAAEEEDEADPKRQK 95
             +E+E A++ EE +   EE   +EEE   +EG  +   K+ AEEE+    +R+K
Sbjct: 1709 WQEKELAQELEELEWDMEELSWKEEELNQEEGKLVEEKKKLAEEEEALAWQREK 1762



 Score = 34.3 bits (77), Expect = 0.022
 Identities = 22/79 (27%), Positives = 43/79 (54%), Gaps = 5/79 (6%)

Query: 18   KEKKEKVEEKASRKERKKEVVEEEENGAEEEEEETAEDGEEEDEGEEEDEEEEEEDDEGP 77
            +E K+  E   S K ++++  +EEE      EEE + +GEE+++   E++   +E+ +  
Sbjct: 1519 EEWKQVWENMLSSKSKEQQYKDEEEVTL---EEEVSREGEEKEQQVTEEQRHIQEEHKWA 1575

Query: 78   AL--KRAAEEEDEADPKRQ 94
             +  KRA  E+  A  +R+
Sbjct: 1576 RIHRKRARAEKKRAQEERK 1594



 Score = 34.3 bits (77), Expect = 0.022
 Identities = 23/65 (35%), Positives = 31/65 (47%), Gaps = 2/65 (3%)

Query: 2    SEKSVEAAAELSAKDLKEKKEKVEEKASRKERKKEVVEEEENGAEEEEEETAEDGEEEDE 61
            SEK  E   +   K L  K+ K+  K  R   K+E + EEE+    +  E   D EEE  
Sbjct: 2126 SEKRSELTKD--EKKLARKQRKLANKMRRMINKEEKMTEEESKLARKHSEVILDDEEEGG 2183

Query: 62   GEEED 66
             EEE+
Sbjct: 2184 IEEEE 2188



 Score = 33.5 bits (75), Expect = 0.037
 Identities = 22/82 (26%), Positives = 44/82 (53%), Gaps = 2/82 (2%)

Query: 17   LKEKKEKVEEKASRKERKKEVVEEEENGAEEEEEETAEDGEEEDEGEEEDEEEEEEDDEG 76
            L E+K+K+ E+      ++E + EEE    +EEE   +  E+E   + +++  EEE+  G
Sbjct: 1742 LVEEKKKLAEEEEALAWQREKLSEEETKLAQEEELLIQ--EKEKLAQHKEKMPEEEERLG 1799

Query: 77   PALKRAAEEEDEADPKRQKTEN 98
               ++  E++ +   KR++  N
Sbjct: 1800 RKREQLIEKKMKLAQKRERWIN 1821



 Score = 32.3 bits (72), Expect = 0.082
 Identities = 20/93 (21%), Positives = 48/93 (51%)

Query: 2    SEKSVEAAAELSAKDLKEKKEKVEEKASRKERKKEVVEEEENGAEEEEEETAEDGEEEDE 61
            + KS +A  E   K L +++EK+ +   +   ++E+++E++    EE ++  E+      
Sbjct: 1474 TRKSWKAWKEEWEKRLLQEEEKLHQAGEKLSPEEEMLQEDKKLKWEEWKQVWENMLSSKS 1533

Query: 62   GEEEDEEEEEEDDEGPALKRAAEEEDEADPKRQ 94
             E++ ++EEE   E    +   E+E +   +++
Sbjct: 1534 KEQQYKDEEEVTLEEEVSREGEEKEQQVTEEQR 1566



 Score = 32.3 bits (72), Expect = 0.082
 Identities = 20/85 (23%), Positives = 44/85 (51%), Gaps = 2/85 (2%)

Query: 11   ELSAKDLKEKKEKVEEKASRKERKKEVVEEEENGAEEEEEETAEDGEEEDEGEEEDEEEE 70
            E   ++L  K+E++ ++  +   +K+ + EEE     + E+ +E  EE    +EE+   +
Sbjct: 1722 EWDMEELSWKEEELNQEEGKLVEEKKKLAEEEEALAWQREKLSE--EETKLAQEEELLIQ 1779

Query: 71   EEDDEGPALKRAAEEEDEADPKRQK 95
            E++      ++  EEE+    KR++
Sbjct: 1780 EKEKLAQHKEKMPEEEERLGRKREQ 1804



 Score = 28.9 bits (63), Expect = 0.91
 Identities = 23/95 (24%), Positives = 46/95 (48%), Gaps = 2/95 (2%)

Query: 3    EKSVEAAAELSAKDLKEKKEKVEEKASRKERKK--EVVEEEENGAEEEEEETAEDGEEED 60
            E+ ++   +L  ++ K+  E +    S++++ K  E V  EE  + E EE+  +  EE+ 
Sbjct: 1507 EEMLQEDKKLKWEEWKQVWENMLSSKSKEQQYKDEEEVTLEEEVSREGEEKEQQVTEEQR 1566

Query: 61   EGEEEDEEEEEEDDEGPALKRAAEEEDEADPKRQK 95
              +EE +          A K+ A+EE +   + +K
Sbjct: 1567 HIQEEHKWARIHRKRARAEKKRAQEERKLAQEEEK 1601



 Score = 28.5 bits (62), Expect = 1.2
 Identities = 21/77 (27%), Positives = 32/77 (41%)

Query: 19   EKKEKVEEKASRKERKKEVVEEEENGAEEEEEETAEDGEEEDEGEEEDEEEEEEDDEGPA 78
            EKK   EE+   +E +K   EE +   EE +   A     +D+ E    E +    E   
Sbjct: 1585 EKKRAQEERKLAQEEEKLAQEERQLAQEERKLAQAYVKITQDDREMAQAEGKFAQKEETL 1644

Query: 79   LKRAAEEEDEADPKRQK 95
             +R  +   EA+   QK
Sbjct: 1645 AQRGEKLSQEAEKLAQK 1661



 Score = 28.1 bits (61), Expect = 1.6
 Identities = 22/69 (31%), Positives = 36/69 (52%), Gaps = 6/69 (8%)

Query: 5    SVEAAAELSAKDLK---EKKEKVEEKASRKERKKEVVEEEENGAEEEEEETAEDGEEEDE 61
            +V    E+S K+ K   +K  K   KA +KERK   ++ E     +EE + +E+ EE   
Sbjct: 1380 NVTMGKEISKKEEKKTFQKSPKQGRKAVQKERKVGKIKREMT---KEERDMSEEVEEMAT 1436

Query: 62   GEEEDEEEE 70
             EE+  ++E
Sbjct: 1437 LEEKVVKQE 1445



 Score = 28.1 bits (61), Expect = 1.6
 Identities = 18/57 (31%), Positives = 33/57 (57%), Gaps = 1/57 (1%)

Query: 15   KDLKEKKEKVEEKASRKERKKEVVEEEENGAEEEEEETAEDGEEEDEGEEEDEEEEE 71
            K++ +K+EK   + S K+ +K V +E + G + + E T E+ +  +E EE    EE+
Sbjct: 1385 KEISKKEEKKTFQKSPKQGRKAVQKERKVG-KIKREMTKEERDMSEEVEEMATLEEK 1440



 Score = 28.1 bits (61), Expect = 1.6
 Identities = 22/73 (30%), Positives = 42/73 (57%), Gaps = 6/73 (8%)

Query: 22   EKVEEKASRKE----RKKEVVEE-EENGAEEEEEETAEDGEEEDEGE-EEDEEEEEEDDE 75
            +KVEE   R++    ++KE+ +E EE   + EE    E+   ++EG+  E++++  E++E
Sbjct: 1695 QKVEELPQREQNLDWQEKELAQELEELEWDMEELSWKEEELNQEEGKLVEEKKKLAEEEE 1754

Query: 76   GPALKRAAEEEDE 88
              A +R    E+E
Sbjct: 1755 ALAWQREKLSEEE 1767



 Score = 27.7 bits (60), Expect = 2.0
 Identities = 18/83 (21%), Positives = 41/83 (49%), Gaps = 7/83 (8%)

Query: 10   AELSAKDLKEKKEKVEEKASRKERKKEVVEEEENGAEEEEE------ETAEDGEEEDEGE 63
            A +  K  + +K++ +E+    + ++++ +EE   A+EE +      +  +D  E  + E
Sbjct: 1575 ARIHRKRARAEKKRAQEERKLAQEEEKLAQEERQLAQEERKLAQAYVKITQDDREMAQAE 1634

Query: 64   EEDEEEEEE-DDEGPALKRAAEE 85
             +  ++EE     G  L + AE+
Sbjct: 1635 GKFAQKEETLAQRGEKLSQEAEK 1657


>gi|105990539 neurofilament, light polypeptide 68kDa [Homo sapiens]
          Length = 543

 Score = 57.4 bits (137), Expect = 2e-09
 Identities = 35/89 (39%), Positives = 52/89 (58%), Gaps = 4/89 (4%)

Query: 3   EKSVEAAAELSAKDLKEKKEKVEEKASRKERKKEVVEEEENGAEEEEEETAEDGEEEDEG 62
           E+++EAA    AKD    + + EE+   KE  +E    EE  A +EE E A++ EE  EG
Sbjct: 455 EETIEAAKAEEAKDEPPSEGEAEEEEKDKEEAEEEEAAEEEEAAKEESEEAKEEEEGGEG 514

Query: 63  EEEDE----EEEEEDDEGPALKRAAEEED 87
           EE +E    EEEE+  EG   ++AA+++D
Sbjct: 515 EEGEETKEAEEEEKKVEGAGEEQAAKKKD 543



 Score = 48.1 bits (113), Expect = 1e-06
 Identities = 37/98 (37%), Positives = 50/98 (51%), Gaps = 8/98 (8%)

Query: 1   MSEKSVEAAAELSAKDLKEKKEKVEEKASRKERKKEV-----VEEEENGAEE-EEEETAE 54
           MS +S  +      ++ + + E+  E A  +E K E       EEEE   EE EEEE AE
Sbjct: 434 MSTRSFPSYYTSHVQEEQIEVEETIEAAKAEEAKDEPPSEGEAEEEEKDKEEAEEEEAAE 493

Query: 55  DGEEEDEGEEEDEEEEE--EDDEGPALKRAAEEEDEAD 90
           + E   E  EE +EEEE  E +EG   K A EEE + +
Sbjct: 494 EEEAAKEESEEAKEEEEGGEGEEGEETKEAEEEEKKVE 531



 Score = 46.2 bits (108), Expect = 6e-06
 Identities = 27/85 (31%), Positives = 45/85 (52%), Gaps = 4/85 (4%)

Query: 17  LKEKKEKVEEKASRKERKKEVVEEEENGAEEEEEETAEDGEEEDEGEEE----DEEEEEE 72
           ++E++ +VEE     + ++   E    G  EEEE+  E+ EEE+  EEE    +E EE +
Sbjct: 447 VQEEQIEVEETIEAAKAEEAKDEPPSEGEAEEEEKDKEEAEEEEAAEEEEAAKEESEEAK 506

Query: 73  DDEGPALKRAAEEEDEADPKRQKTE 97
           ++E        EE  EA+ + +K E
Sbjct: 507 EEEEGGEGEEGEETKEAEEEEKKVE 531



 Score = 38.5 bits (88), Expect = 0.001
 Identities = 24/70 (34%), Positives = 39/70 (55%), Gaps = 7/70 (10%)

Query: 34  KKEVVEEEEN----GAEEEEEETAEDGEEEDEGEEEDEEEEEEDDEGPALKRAAEEEDEA 89
           ++E +E EE      AEE ++E   +GE E   EEE ++EE E++E    + AA+EE E 
Sbjct: 448 QEEQIEVEETIEAAKAEEAKDEPPSEGEAE---EEEKDKEEAEEEEAAEEEEAAKEESEE 504

Query: 90  DPKRQKTENG 99
             + ++   G
Sbjct: 505 AKEEEEGGEG 514



 Score = 36.2 bits (82), Expect = 0.006
 Identities = 24/63 (38%), Positives = 30/63 (47%), Gaps = 5/63 (7%)

Query: 40  EEENGAEEEEEETAEDGEEEDEGEEEDEEEEEEDDEGPALKRAAEEEDEADPKRQKTENG 99
           +EE    EE  E A+  E +DE   E E EEEE D     K  AEEE+ A+ +    E  
Sbjct: 448 QEEQIEVEETIEAAKAEEAKDEPPSEGEAEEEEKD-----KEEAEEEEAAEEEEAAKEES 502

Query: 100 ASA 102
             A
Sbjct: 503 EEA 505


>gi|157738649 neurofilament, medium polypeptide 150kDa isoform 1
           [Homo sapiens]
          Length = 916

 Score = 57.0 bits (136), Expect = 3e-09
 Identities = 41/118 (34%), Positives = 59/118 (50%), Gaps = 27/118 (22%)

Query: 7   EAAAELSAKDLKEKKEKV------EEKASRKERKKEVVEEEENGAEEEEEETA------- 53
           E   E   +D K + E+       E   S KE KKE  EE+E   E EEEE A       
Sbjct: 455 EIIEETKVEDEKSEMEEALTAITEELAVSMKEEKKEAAEEKEEEPEAEEEEVAAKKSPVK 514

Query: 54  --------EDGE-EEDEGEEEDEEEEE-----EDDEGPALKRAAEEEDEADPKRQKTE 97
                   E+GE EE+EG+EE+EEE+E     + +EG + K  + E++E + +  +TE
Sbjct: 515 ATAPEVKEEEGEKEEEEGQEEEEEEDEGAKSDQAEEGGSEKEGSSEKEEGEQEEGETE 572



 Score = 47.8 bits (112), Expect = 2e-06
 Identities = 32/103 (31%), Positives = 51/103 (49%), Gaps = 20/103 (19%)

Query: 15  KDLKEKKEKVEEKASRKERKKEVVEEEENGAEEEEEETAEDGEEEDEGEEE--------- 65
           +++ E+ +  +EK+  +E    + EE     +EE++E AE+ EEE E EEE         
Sbjct: 454 EEIIEETKVEDEKSEMEEALTAITEELAVSMKEEKKEAAEEKEEEPEAEEEEVAAKKSPV 513

Query: 66  --------DEEEEEEDDEGPALKRAAEEEDEADPKRQKTENGA 100
                   +EE E+E++EG   +   EEEDE     Q  E G+
Sbjct: 514 KATAPEVKEEEGEKEEEEG---QEEEEEEDEGAKSDQAEEGGS 553



 Score = 46.6 bits (109), Expect = 4e-06
 Identities = 30/84 (35%), Positives = 51/84 (60%), Gaps = 2/84 (2%)

Query: 19  EKKEKVEEKASRKERKKEVVEEEENGAEEEEEETAEDGEEEDEGE-EEDEEEEEEDDEGP 77
           +++E+ E++ ++ ++ +E   E+E  +E+EE E  E+GE E E E EE E +EE+  E  
Sbjct: 533 QEEEEEEDEGAKSDQAEEGGSEKEGSSEKEEGE-QEEGETEAEAEGEEAEAKEEKKVEEK 591

Query: 78  ALKRAAEEEDEADPKRQKTENGAS 101
           + + A +EE  AD K +K E   S
Sbjct: 592 SEEVATKEELVADAKVEKPEKAKS 615



 Score = 38.1 bits (87), Expect = 0.002
 Identities = 24/79 (30%), Positives = 40/79 (50%), Gaps = 1/79 (1%)

Query: 21  KEKVEEKASRKERKKEVVEEEENGAEEEEEETAEDGEEEDEGEEEDEEEEEEDDEGPALK 80
           K  VEEK      K  V E+ ++   +   E A+   E  +GE+++EEE+E  +     K
Sbjct: 658 KSPVEEKGKSPVSKSPVEEKAKSPVPKSPVEEAKSKAEVGKGEQKEEEEKEVKEAPKEEK 717

Query: 81  RAAEEEDEAD-PKRQKTEN 98
              +EE   D P+++K E+
Sbjct: 718 VEKKEEKPKDVPEKKKAES 736



 Score = 37.4 bits (85), Expect = 0.003
 Identities = 29/106 (27%), Positives = 47/106 (44%), Gaps = 14/106 (13%)

Query: 11  ELSAKDLKEKKEKVEEKASRKERKKEVVEEEENGAEEEEEETAEDGEEEDEGEEEDEEEE 70
           ++ A  LK + + VEE     + + E  E EE      EE      EE+ E  EE EEE 
Sbjct: 440 KVEAPKLKVQHKFVEEIIEETKVEDEKSEMEEALTAITEELAVSMKEEKKEAAEEKEEEP 499

Query: 71  EEDDEGPALKRA--------------AEEEDEADPKRQKTENGASA 102
           E ++E  A K++               +EE+E   + ++ + GA +
Sbjct: 500 EAEEEEVAAKKSPVKATAPEVKEEEGEKEEEEGQEEEEEEDEGAKS 545



 Score = 37.4 bits (85), Expect = 0.003
 Identities = 30/101 (29%), Positives = 47/101 (46%), Gaps = 3/101 (2%)

Query: 3   EKSVEAAAELSAKDLKEKKEKVEEKASRKERKKEVVEEEENGAEEEEEETAEDGEEEDEG 62
           E   EA AE    + KE+K KVEEK+     K+E+V + +    E+ +        E++G
Sbjct: 568 EGETEAEAEGEEAEAKEEK-KVEEKSEEVATKEELVADAKVEKPEKAKSPVPKSPVEEKG 626

Query: 63  EEE-DEEEEEEDDEGPALKRAAEEEDEAD-PKRQKTENGAS 101
           +    +   EE  + P  K   EE+ ++  PK    E G S
Sbjct: 627 KSPVPKSPVEEKGKSPVPKSPVEEKGKSPVPKSPVEEKGKS 667



 Score = 37.4 bits (85), Expect = 0.003
 Identities = 28/82 (34%), Positives = 41/82 (50%), Gaps = 12/82 (14%)

Query: 7   EAAAEL-----SAKDLKEKKEKVEEKASRKERKKEVVEEEENGAEEEEEETAEDGEEED- 60
           EA AE+     S K   EK+ K E K  ++E++KE    E    EE  ++ A+   +ED 
Sbjct: 741 EAVAEVVTITKSVKVHLEKETKEEGKPLQQEKEKEKAGGEGGSEEEGSDKGAKGSRKEDI 800

Query: 61  ------EGEEEDEEEEEEDDEG 76
                 EG+EE E+E +E   G
Sbjct: 801 AVNGEVEGKEEVEQETKEKGSG 822



 Score = 36.2 bits (82), Expect = 0.006
 Identities = 27/101 (26%), Positives = 47/101 (46%), Gaps = 5/101 (4%)

Query: 2   SEKSVEAAAELSAKDLKEKKEKVEEKASRKERKKEVVEEEENGAEEEEEETAEDGEEEDE 61
           S+++ E  +E      KE+ E+ E +   +   +E   +EE   EE+ EE A     ++E
Sbjct: 545 SDQAEEGGSEKEGSSEKEEGEQEEGETEAEAEGEEAEAKEEKKVEEKSEEVA----TKEE 600

Query: 62  GEEEDEEEEEEDDEGPALKRAAEEEDEAD-PKRQKTENGAS 101
              + + E+ E  + P  K   EE+ ++  PK    E G S
Sbjct: 601 LVADAKVEKPEKAKSPVPKSPVEEKGKSPVPKSPVEEKGKS 641



 Score = 35.4 bits (80), Expect = 0.010
 Identities = 29/117 (24%), Positives = 59/117 (50%), Gaps = 21/117 (17%)

Query: 4   KSVEAAAELSAKDLKEKKEKV------EEKASRKERK-KEVVEEEENGAEEEEEETAE-- 54
           +  ++ AE+   + KE++EK       EEK  +KE K K+V E+++  +  +EE  AE  
Sbjct: 688 EEAKSKAEVGKGEQKEEEEKEVKEAPKEEKVEKKEEKPKDVPEKKKAESPVKEEAVAEVV 747

Query: 55  ----------DGEEEDEGE--EEDEEEEEEDDEGPALKRAAEEEDEADPKRQKTENG 99
                     + E ++EG+  ++++E+E+   EG + +  +++  +   K     NG
Sbjct: 748 TITKSVKVHLEKETKEEGKPLQQEKEKEKAGGEGGSEEEGSDKGAKGSRKEDIAVNG 804



 Score = 31.6 bits (70), Expect = 0.14
 Identities = 28/120 (23%), Positives = 53/120 (44%), Gaps = 21/120 (17%)

Query: 1   MSEKSVEAAAELSAKDLKEKKEKVEEKASRKERKKEVVEEEENGAEEEEEETAEDGEEED 60
           + EK+     +   ++ K K E V +   ++E +KEV E  +    E++EE  +D  E+ 
Sbjct: 674 VEEKAKSPVPKSPVEEAKSKAE-VGKGEQKEEEEKEVKEAPKEEKVEKKEEKPKDVPEKK 732

Query: 61  EGEEEDEE-----------------EEEEDDEGPALKRAAEEE---DEADPKRQKTENGA 100
           + E   +E                 E+E  +EG  L++  E+E    E   + + ++ GA
Sbjct: 733 KAESPVKEEAVAEVVTITKSVKVHLEKETKEEGKPLQQEKEKEKAGGEGGSEEEGSDKGA 792



 Score = 30.0 bits (66), Expect = 0.41
 Identities = 22/75 (29%), Positives = 38/75 (50%), Gaps = 12/75 (16%)

Query: 1   MSEKSVEAAAELSAKDLKEK-------KEKVEEKASRKERKKEV-VEEEENGAEEEEEET 52
           + +++ E    L  +  KEK       +E+  +K ++  RK+++ V  E  G EE E+ET
Sbjct: 757 LEKETKEEGKPLQQEKEKEKAGGEGGSEEEGSDKGAKGSRKEDIAVNGEVEGKEEVEQET 816

Query: 53  AEDGEEEDEGEEEDE 67
            E G     G EE++
Sbjct: 817 KEKGS----GREEEK 827



 Score = 29.6 bits (65), Expect = 0.53
 Identities = 28/109 (25%), Positives = 50/109 (45%), Gaps = 13/109 (11%)

Query: 3   EKSVEAAAELSAKDLKEKKEK---VEEKA---------SRKERKKEVVEEEENGAEEEEE 50
           E+ VE   E   KD+ EKK+    V+E+A         S K   ++  +EE    ++E+E
Sbjct: 715 EEKVEKKEE-KPKDVPEKKKAESPVKEEAVAEVVTITKSVKVHLEKETKEEGKPLQQEKE 773

Query: 51  ETAEDGEEEDEGEEEDEEEEEEDDEGPALKRAAEEEDEADPKRQKTENG 99
           +    GE   E E  D+  +    E  A+    E ++E + + ++  +G
Sbjct: 774 KEKAGGEGGSEEEGSDKGAKGSRKEDIAVNGEVEGKEEVEQETKEKGSG 822



 Score = 27.7 bits (60), Expect = 2.0
 Identities = 28/82 (34%), Positives = 42/82 (51%), Gaps = 13/82 (15%)

Query: 18  KEKKEKVEEKASRKERK--KEVVEE---EENGAEEEEEETAEDGEEEDEGEEEDEE--EE 70
           K +K KVE    + + K  +E++EE   E+  +E EE  TA   E     +EE +E  EE
Sbjct: 435 KIQKPKVEAPKLKVQHKFVEEIIEETKVEDEKSEMEEALTAITEELAVSMKEEKKEAAEE 494

Query: 71  EEDDEGPALKRAAEEEDEADPK 92
           +E++        AEEE+ A  K
Sbjct: 495 KEEEP------EAEEEEVAAKK 510



 Score = 25.8 bits (55), Expect = 7.7
 Identities = 16/59 (27%), Positives = 31/59 (52%)

Query: 11  ELSAKDLKEKKEKVEEKASRKERKKEVVEEEENGAEEEEEETAEDGEEEDEGEEEDEEE 69
           +LS  D K+  +K EEK    +  +++  E  +GA +   ++    ++ +E EE  EE+
Sbjct: 835 DLSPADEKKGGDKSEEKVVVTKTVEKITSEGGDGATKYITKSVTVTQKVEEHEETFEEK 893


>gi|157738641 neurofilament, medium polypeptide 150kDa isoform 2
           [Homo sapiens]
          Length = 540

 Score = 57.0 bits (136), Expect = 3e-09
 Identities = 41/118 (34%), Positives = 59/118 (50%), Gaps = 27/118 (22%)

Query: 7   EAAAELSAKDLKEKKEKV------EEKASRKERKKEVVEEEENGAEEEEEETA------- 53
           E   E   +D K + E+       E   S KE KKE  EE+E   E EEEE A       
Sbjct: 79  EIIEETKVEDEKSEMEEALTAITEELAVSMKEEKKEAAEEKEEEPEAEEEEVAAKKSPVK 138

Query: 54  --------EDGE-EEDEGEEEDEEEEE-----EDDEGPALKRAAEEEDEADPKRQKTE 97
                   E+GE EE+EG+EE+EEE+E     + +EG + K  + E++E + +  +TE
Sbjct: 139 ATAPEVKEEEGEKEEEEGQEEEEEEDEGAKSDQAEEGGSEKEGSSEKEEGEQEEGETE 196



 Score = 47.8 bits (112), Expect = 2e-06
 Identities = 32/103 (31%), Positives = 51/103 (49%), Gaps = 20/103 (19%)

Query: 15  KDLKEKKEKVEEKASRKERKKEVVEEEENGAEEEEEETAEDGEEEDEGEEE--------- 65
           +++ E+ +  +EK+  +E    + EE     +EE++E AE+ EEE E EEE         
Sbjct: 78  EEIIEETKVEDEKSEMEEALTAITEELAVSMKEEKKEAAEEKEEEPEAEEEEVAAKKSPV 137

Query: 66  --------DEEEEEEDDEGPALKRAAEEEDEADPKRQKTENGA 100
                   +EE E+E++EG   +   EEEDE     Q  E G+
Sbjct: 138 KATAPEVKEEEGEKEEEEG---QEEEEEEDEGAKSDQAEEGGS 177



 Score = 46.6 bits (109), Expect = 4e-06
 Identities = 30/84 (35%), Positives = 51/84 (60%), Gaps = 2/84 (2%)

Query: 19  EKKEKVEEKASRKERKKEVVEEEENGAEEEEEETAEDGEEEDEGE-EEDEEEEEEDDEGP 77
           +++E+ E++ ++ ++ +E   E+E  +E+EE E  E+GE E E E EE E +EE+  E  
Sbjct: 157 QEEEEEEDEGAKSDQAEEGGSEKEGSSEKEEGE-QEEGETEAEAEGEEAEAKEEKKVEEK 215

Query: 78  ALKRAAEEEDEADPKRQKTENGAS 101
           + + A +EE  AD K +K E   S
Sbjct: 216 SEEVATKEELVADAKVEKPEKAKS 239



 Score = 38.1 bits (87), Expect = 0.002
 Identities = 24/79 (30%), Positives = 40/79 (50%), Gaps = 1/79 (1%)

Query: 21  KEKVEEKASRKERKKEVVEEEENGAEEEEEETAEDGEEEDEGEEEDEEEEEEDDEGPALK 80
           K  VEEK      K  V E+ ++   +   E A+   E  +GE+++EEE+E  +     K
Sbjct: 282 KSPVEEKGKSPVSKSPVEEKAKSPVPKSPVEEAKSKAEVGKGEQKEEEEKEVKEAPKEEK 341

Query: 81  RAAEEEDEAD-PKRQKTEN 98
              +EE   D P+++K E+
Sbjct: 342 VEKKEEKPKDVPEKKKAES 360



 Score = 37.4 bits (85), Expect = 0.003
 Identities = 29/106 (27%), Positives = 47/106 (44%), Gaps = 14/106 (13%)

Query: 11  ELSAKDLKEKKEKVEEKASRKERKKEVVEEEENGAEEEEEETAEDGEEEDEGEEEDEEEE 70
           ++ A  LK + + VEE     + + E  E EE      EE      EE+ E  EE EEE 
Sbjct: 64  KVEAPKLKVQHKFVEEIIEETKVEDEKSEMEEALTAITEELAVSMKEEKKEAAEEKEEEP 123

Query: 71  EEDDEGPALKRA--------------AEEEDEADPKRQKTENGASA 102
           E ++E  A K++               +EE+E   + ++ + GA +
Sbjct: 124 EAEEEEVAAKKSPVKATAPEVKEEEGEKEEEEGQEEEEEEDEGAKS 169



 Score = 37.4 bits (85), Expect = 0.003
 Identities = 30/101 (29%), Positives = 47/101 (46%), Gaps = 3/101 (2%)

Query: 3   EKSVEAAAELSAKDLKEKKEKVEEKASRKERKKEVVEEEENGAEEEEEETAEDGEEEDEG 62
           E   EA AE    + KE+K KVEEK+     K+E+V + +    E+ +        E++G
Sbjct: 192 EGETEAEAEGEEAEAKEEK-KVEEKSEEVATKEELVADAKVEKPEKAKSPVPKSPVEEKG 250

Query: 63  EEE-DEEEEEEDDEGPALKRAAEEEDEAD-PKRQKTENGAS 101
           +    +   EE  + P  K   EE+ ++  PK    E G S
Sbjct: 251 KSPVPKSPVEEKGKSPVPKSPVEEKGKSPVPKSPVEEKGKS 291



 Score = 37.4 bits (85), Expect = 0.003
 Identities = 28/82 (34%), Positives = 41/82 (50%), Gaps = 12/82 (14%)

Query: 7   EAAAEL-----SAKDLKEKKEKVEEKASRKERKKEVVEEEENGAEEEEEETAEDGEEED- 60
           EA AE+     S K   EK+ K E K  ++E++KE    E    EE  ++ A+   +ED 
Sbjct: 365 EAVAEVVTITKSVKVHLEKETKEEGKPLQQEKEKEKAGGEGGSEEEGSDKGAKGSRKEDI 424

Query: 61  ------EGEEEDEEEEEEDDEG 76
                 EG+EE E+E +E   G
Sbjct: 425 AVNGEVEGKEEVEQETKEKGSG 446



 Score = 36.2 bits (82), Expect = 0.006
 Identities = 27/101 (26%), Positives = 47/101 (46%), Gaps = 5/101 (4%)

Query: 2   SEKSVEAAAELSAKDLKEKKEKVEEKASRKERKKEVVEEEENGAEEEEEETAEDGEEEDE 61
           S+++ E  +E      KE+ E+ E +   +   +E   +EE   EE+ EE A     ++E
Sbjct: 169 SDQAEEGGSEKEGSSEKEEGEQEEGETEAEAEGEEAEAKEEKKVEEKSEEVA----TKEE 224

Query: 62  GEEEDEEEEEEDDEGPALKRAAEEEDEAD-PKRQKTENGAS 101
              + + E+ E  + P  K   EE+ ++  PK    E G S
Sbjct: 225 LVADAKVEKPEKAKSPVPKSPVEEKGKSPVPKSPVEEKGKS 265



 Score = 35.4 bits (80), Expect = 0.010
 Identities = 29/117 (24%), Positives = 59/117 (50%), Gaps = 21/117 (17%)

Query: 4   KSVEAAAELSAKDLKEKKEKV------EEKASRKERK-KEVVEEEENGAEEEEEETAE-- 54
           +  ++ AE+   + KE++EK       EEK  +KE K K+V E+++  +  +EE  AE  
Sbjct: 312 EEAKSKAEVGKGEQKEEEEKEVKEAPKEEKVEKKEEKPKDVPEKKKAESPVKEEAVAEVV 371

Query: 55  ----------DGEEEDEGE--EEDEEEEEEDDEGPALKRAAEEEDEADPKRQKTENG 99
                     + E ++EG+  ++++E+E+   EG + +  +++  +   K     NG
Sbjct: 372 TITKSVKVHLEKETKEEGKPLQQEKEKEKAGGEGGSEEEGSDKGAKGSRKEDIAVNG 428



 Score = 31.6 bits (70), Expect = 0.14
 Identities = 28/120 (23%), Positives = 53/120 (44%), Gaps = 21/120 (17%)

Query: 1   MSEKSVEAAAELSAKDLKEKKEKVEEKASRKERKKEVVEEEENGAEEEEEETAEDGEEED 60
           + EK+     +   ++ K K E V +   ++E +KEV E  +    E++EE  +D  E+ 
Sbjct: 298 VEEKAKSPVPKSPVEEAKSKAE-VGKGEQKEEEEKEVKEAPKEEKVEKKEEKPKDVPEKK 356

Query: 61  EGEEEDEE-----------------EEEEDDEGPALKRAAEEE---DEADPKRQKTENGA 100
           + E   +E                 E+E  +EG  L++  E+E    E   + + ++ GA
Sbjct: 357 KAESPVKEEAVAEVVTITKSVKVHLEKETKEEGKPLQQEKEKEKAGGEGGSEEEGSDKGA 416



 Score = 30.0 bits (66), Expect = 0.41
 Identities = 22/75 (29%), Positives = 38/75 (50%), Gaps = 12/75 (16%)

Query: 1   MSEKSVEAAAELSAKDLKEK-------KEKVEEKASRKERKKEV-VEEEENGAEEEEEET 52
           + +++ E    L  +  KEK       +E+  +K ++  RK+++ V  E  G EE E+ET
Sbjct: 381 LEKETKEEGKPLQQEKEKEKAGGEGGSEEEGSDKGAKGSRKEDIAVNGEVEGKEEVEQET 440

Query: 53  AEDGEEEDEGEEEDE 67
            E G     G EE++
Sbjct: 441 KEKGS----GREEEK 451



 Score = 29.6 bits (65), Expect = 0.53
 Identities = 28/109 (25%), Positives = 50/109 (45%), Gaps = 13/109 (11%)

Query: 3   EKSVEAAAELSAKDLKEKKEK---VEEKA---------SRKERKKEVVEEEENGAEEEEE 50
           E+ VE   E   KD+ EKK+    V+E+A         S K   ++  +EE    ++E+E
Sbjct: 339 EEKVEKKEE-KPKDVPEKKKAESPVKEEAVAEVVTITKSVKVHLEKETKEEGKPLQQEKE 397

Query: 51  ETAEDGEEEDEGEEEDEEEEEEDDEGPALKRAAEEEDEADPKRQKTENG 99
           +    GE   E E  D+  +    E  A+    E ++E + + ++  +G
Sbjct: 398 KEKAGGEGGSEEEGSDKGAKGSRKEDIAVNGEVEGKEEVEQETKEKGSG 446



 Score = 27.7 bits (60), Expect = 2.0
 Identities = 28/82 (34%), Positives = 42/82 (51%), Gaps = 13/82 (15%)

Query: 18  KEKKEKVEEKASRKERK--KEVVEE---EENGAEEEEEETAEDGEEEDEGEEEDEE--EE 70
           K +K KVE    + + K  +E++EE   E+  +E EE  TA   E     +EE +E  EE
Sbjct: 59  KIQKPKVEAPKLKVQHKFVEEIIEETKVEDEKSEMEEALTAITEELAVSMKEEKKEAAEE 118

Query: 71  EEDDEGPALKRAAEEEDEADPK 92
           +E++        AEEE+ A  K
Sbjct: 119 KEEEP------EAEEEEVAAKK 134



 Score = 25.8 bits (55), Expect = 7.7
 Identities = 16/59 (27%), Positives = 31/59 (52%)

Query: 11  ELSAKDLKEKKEKVEEKASRKERKKEVVEEEENGAEEEEEETAEDGEEEDEGEEEDEEE 69
           +LS  D K+  +K EEK    +  +++  E  +GA +   ++    ++ +E EE  EE+
Sbjct: 459 DLSPADEKKGGDKSEEKVVVTKTVEKITSEGGDGATKYITKSVTVTQKVEEHEETFEEK 517


>gi|195546902 suppressor of Ty 5 homolog isoform b [Homo sapiens]
          Length = 1083

 Score = 56.6 bits (135), Expect = 4e-09
 Identities = 32/67 (47%), Positives = 43/67 (64%), Gaps = 1/67 (1%)

Query: 14 AKDLKEKKEKVEEKASRKERKKEVVEEEENGAEEEEEETAEDGEEEDEGEEEDEEEEEED 73
          ++D    +E+  E++S  E + EV EE  + A  E+EE  ED EEE+E EE DEEEEEED
Sbjct: 4  SEDSNFSEEEDSERSSDGE-EAEVDEERRSAAGSEKEEEPEDEEEEEEEEEYDEEEEEED 62

Query: 74 DEGPALK 80
          D+ P  K
Sbjct: 63 DDRPPKK 69



 Score = 45.1 bits (105), Expect = 1e-05
 Identities = 27/91 (29%), Positives = 48/91 (52%), Gaps = 1/91 (1%)

Query: 10  AELSAKDLKEKKEKVEEKASRKERKKEVVEEEENGAEEEEEETAEDGEEEDEGEEEDEEE 69
           +  S ++  E+    EE    +ER+     E+E   E+EEEE  E+  +E+E EE+D+  
Sbjct: 7   SNFSEEEDSERSSDGEEAEVDEERRSAAGSEKEEEPEDEEEEEEEEEYDEEEEEEDDDRP 66

Query: 70  EEEDDEGPALKRAAEEEDEADPKRQKTENGA 100
            ++   G  +   A+ +DE + + Q  E+GA
Sbjct: 67  PKKPRHGGFILDEADVDDEYEDEDQ-WEDGA 96



 Score = 35.8 bits (81), Expect = 0.007
 Identities = 31/114 (27%), Positives = 52/114 (45%), Gaps = 22/114 (19%)

Query: 2   SEKSVEAAAELSA--KDLKEKKEKVEEKASRKERKKEVVEEEENGAEEEEEETAEDG--- 56
           S  S E  +E S+  ++ +  +E+     S KE + E  EEEE   E +EEE  ED    
Sbjct: 7   SNFSEEEDSERSSDGEEAEVDEERRSAAGSEKEEEPEDEEEEEEEEEYDEEEEEEDDDRP 66

Query: 57  -----------EEEDEGEEEDEEEEEEDDEGPALKRAAE------EEDEADPKR 93
                      +E D  +E ++E++ ED     L++A+       +ED +  +R
Sbjct: 67  PKKPRHGGFILDEADVDDEYEDEDQWEDGAEDILEKASNIDNVVLDEDRSGARR 120


>gi|195546900 suppressor of Ty 5 homolog isoform a [Homo sapiens]
          Length = 1087

 Score = 56.6 bits (135), Expect = 4e-09
 Identities = 32/67 (47%), Positives = 43/67 (64%), Gaps = 1/67 (1%)

Query: 14 AKDLKEKKEKVEEKASRKERKKEVVEEEENGAEEEEEETAEDGEEEDEGEEEDEEEEEED 73
          ++D    +E+  E++S  E + EV EE  + A  E+EE  ED EEE+E EE DEEEEEED
Sbjct: 4  SEDSNFSEEEDSERSSDGE-EAEVDEERRSAAGSEKEEEPEDEEEEEEEEEYDEEEEEED 62

Query: 74 DEGPALK 80
          D+ P  K
Sbjct: 63 DDRPPKK 69



 Score = 45.1 bits (105), Expect = 1e-05
 Identities = 27/91 (29%), Positives = 48/91 (52%), Gaps = 1/91 (1%)

Query: 10  AELSAKDLKEKKEKVEEKASRKERKKEVVEEEENGAEEEEEETAEDGEEEDEGEEEDEEE 69
           +  S ++  E+    EE    +ER+     E+E   E+EEEE  E+  +E+E EE+D+  
Sbjct: 7   SNFSEEEDSERSSDGEEAEVDEERRSAAGSEKEEEPEDEEEEEEEEEYDEEEEEEDDDRP 66

Query: 70  EEEDDEGPALKRAAEEEDEADPKRQKTENGA 100
            ++   G  +   A+ +DE + + Q  E+GA
Sbjct: 67  PKKPRHGGFILDEADVDDEYEDEDQ-WEDGA 96



 Score = 39.3 bits (90), Expect = 7e-04
 Identities = 33/104 (31%), Positives = 50/104 (48%), Gaps = 19/104 (18%)

Query: 2   SEKSVEAAAELSAKDLKEKKEKVEEKASRKERKKEVVEEEENGAEEEEEETAEDGEEED- 60
           S  S E  +E S+   + + ++    A+  E+++E  +EEE   EEEEEE  E+ EEED 
Sbjct: 7   SNFSEEEDSERSSDGEEAEVDEERRSAAGSEKEEEPEDEEE---EEEEEEYDEEEEEEDD 63

Query: 61  ---------------EGEEEDEEEEEEDDEGPALKRAAEEEDEA 89
                          E + +DE E+E+  E  A     +EE EA
Sbjct: 64  DRPPKKPRHGGFILDEADVDDEYEDEDQWEDGAEDILEKEEIEA 107



 Score = 35.4 bits (80), Expect = 0.010
 Identities = 24/100 (24%), Positives = 44/100 (44%), Gaps = 12/100 (12%)

Query: 3   EKSVEAAAELSAKDLKEKKEKVEEKASRKERKKEVVEEEENGAEEEEEETAEDG------ 56
           E+  E +++    ++ E++         +E + E  EEEE   +EEEEE  +D       
Sbjct: 12  EEDSERSSDGEEAEVDEERRSAAGSEKEEEPEDEEEEEEEEEYDEEEEEEDDDRPPKKPR 71

Query: 57  ------EEEDEGEEEDEEEEEEDDEGPALKRAAEEEDEAD 90
                 +E D  +E ++E++ ED     L++   E    D
Sbjct: 72  HGGFILDEADVDDEYEDEDQWEDGAEDILEKEEIEASNID 111



 Score = 29.6 bits (65), Expect = 0.53
 Identities = 24/78 (30%), Positives = 39/78 (50%), Gaps = 6/78 (7%)

Query: 2   SEKSVEAAAELSAKDLKEKKEKVEEKASRKERKKE-----VVEEEENGAEEEEEETAEDG 56
           SEK  E   E   ++ +E  E+ EE+   +  KK      +++E +   E E+E+  EDG
Sbjct: 36  SEKEEEPEDEEEEEEEEEYDEEEEEEDDDRPPKKPRHGGFILDEADVDDEYEDEDQWEDG 95

Query: 57  EEEDEGEEEDEEEEEEDD 74
            E D  E+E+ E    D+
Sbjct: 96  AE-DILEKEEIEASNIDN 112


>gi|161169023 suppressor of Ty 5 homolog isoform a [Homo sapiens]
          Length = 1087

 Score = 56.6 bits (135), Expect = 4e-09
 Identities = 32/67 (47%), Positives = 43/67 (64%), Gaps = 1/67 (1%)

Query: 14 AKDLKEKKEKVEEKASRKERKKEVVEEEENGAEEEEEETAEDGEEEDEGEEEDEEEEEED 73
          ++D    +E+  E++S  E + EV EE  + A  E+EE  ED EEE+E EE DEEEEEED
Sbjct: 4  SEDSNFSEEEDSERSSDGE-EAEVDEERRSAAGSEKEEEPEDEEEEEEEEEYDEEEEEED 62

Query: 74 DEGPALK 80
          D+ P  K
Sbjct: 63 DDRPPKK 69



 Score = 45.1 bits (105), Expect = 1e-05
 Identities = 27/91 (29%), Positives = 48/91 (52%), Gaps = 1/91 (1%)

Query: 10  AELSAKDLKEKKEKVEEKASRKERKKEVVEEEENGAEEEEEETAEDGEEEDEGEEEDEEE 69
           +  S ++  E+    EE    +ER+     E+E   E+EEEE  E+  +E+E EE+D+  
Sbjct: 7   SNFSEEEDSERSSDGEEAEVDEERRSAAGSEKEEEPEDEEEEEEEEEYDEEEEEEDDDRP 66

Query: 70  EEEDDEGPALKRAAEEEDEADPKRQKTENGA 100
            ++   G  +   A+ +DE + + Q  E+GA
Sbjct: 67  PKKPRHGGFILDEADVDDEYEDEDQ-WEDGA 96



 Score = 39.3 bits (90), Expect = 7e-04
 Identities = 33/104 (31%), Positives = 50/104 (48%), Gaps = 19/104 (18%)

Query: 2   SEKSVEAAAELSAKDLKEKKEKVEEKASRKERKKEVVEEEENGAEEEEEETAEDGEEED- 60
           S  S E  +E S+   + + ++    A+  E+++E  +EEE   EEEEEE  E+ EEED 
Sbjct: 7   SNFSEEEDSERSSDGEEAEVDEERRSAAGSEKEEEPEDEEE---EEEEEEYDEEEEEEDD 63

Query: 61  ---------------EGEEEDEEEEEEDDEGPALKRAAEEEDEA 89
                          E + +DE E+E+  E  A     +EE EA
Sbjct: 64  DRPPKKPRHGGFILDEADVDDEYEDEDQWEDGAEDILEKEEIEA 107



 Score = 35.4 bits (80), Expect = 0.010
 Identities = 24/100 (24%), Positives = 44/100 (44%), Gaps = 12/100 (12%)

Query: 3   EKSVEAAAELSAKDLKEKKEKVEEKASRKERKKEVVEEEENGAEEEEEETAEDG------ 56
           E+  E +++    ++ E++         +E + E  EEEE   +EEEEE  +D       
Sbjct: 12  EEDSERSSDGEEAEVDEERRSAAGSEKEEEPEDEEEEEEEEEYDEEEEEEDDDRPPKKPR 71

Query: 57  ------EEEDEGEEEDEEEEEEDDEGPALKRAAEEEDEAD 90
                 +E D  +E ++E++ ED     L++   E    D
Sbjct: 72  HGGFILDEADVDDEYEDEDQWEDGAEDILEKEEIEASNID 111



 Score = 29.6 bits (65), Expect = 0.53
 Identities = 24/78 (30%), Positives = 39/78 (50%), Gaps = 6/78 (7%)

Query: 2   SEKSVEAAAELSAKDLKEKKEKVEEKASRKERKKE-----VVEEEENGAEEEEEETAEDG 56
           SEK  E   E   ++ +E  E+ EE+   +  KK      +++E +   E E+E+  EDG
Sbjct: 36  SEKEEEPEDEEEEEEEEEYDEEEEEEDDDRPPKKPRHGGFILDEADVDDEYEDEDQWEDG 95

Query: 57  EEEDEGEEEDEEEEEEDD 74
            E D  E+E+ E    D+
Sbjct: 96  AE-DILEKEEIEASNIDN 112


>gi|20149524 suppressor of Ty 5 homolog isoform a [Homo sapiens]
          Length = 1087

 Score = 56.6 bits (135), Expect = 4e-09
 Identities = 32/67 (47%), Positives = 43/67 (64%), Gaps = 1/67 (1%)

Query: 14 AKDLKEKKEKVEEKASRKERKKEVVEEEENGAEEEEEETAEDGEEEDEGEEEDEEEEEED 73
          ++D    +E+  E++S  E + EV EE  + A  E+EE  ED EEE+E EE DEEEEEED
Sbjct: 4  SEDSNFSEEEDSERSSDGE-EAEVDEERRSAAGSEKEEEPEDEEEEEEEEEYDEEEEEED 62

Query: 74 DEGPALK 80
          D+ P  K
Sbjct: 63 DDRPPKK 69



 Score = 45.1 bits (105), Expect = 1e-05
 Identities = 27/91 (29%), Positives = 48/91 (52%), Gaps = 1/91 (1%)

Query: 10  AELSAKDLKEKKEKVEEKASRKERKKEVVEEEENGAEEEEEETAEDGEEEDEGEEEDEEE 69
           +  S ++  E+    EE    +ER+     E+E   E+EEEE  E+  +E+E EE+D+  
Sbjct: 7   SNFSEEEDSERSSDGEEAEVDEERRSAAGSEKEEEPEDEEEEEEEEEYDEEEEEEDDDRP 66

Query: 70  EEEDDEGPALKRAAEEEDEADPKRQKTENGA 100
            ++   G  +   A+ +DE + + Q  E+GA
Sbjct: 67  PKKPRHGGFILDEADVDDEYEDEDQ-WEDGA 96



 Score = 39.3 bits (90), Expect = 7e-04
 Identities = 33/104 (31%), Positives = 50/104 (48%), Gaps = 19/104 (18%)

Query: 2   SEKSVEAAAELSAKDLKEKKEKVEEKASRKERKKEVVEEEENGAEEEEEETAEDGEEED- 60
           S  S E  +E S+   + + ++    A+  E+++E  +EEE   EEEEEE  E+ EEED 
Sbjct: 7   SNFSEEEDSERSSDGEEAEVDEERRSAAGSEKEEEPEDEEE---EEEEEEYDEEEEEEDD 63

Query: 61  ---------------EGEEEDEEEEEEDDEGPALKRAAEEEDEA 89
                          E + +DE E+E+  E  A     +EE EA
Sbjct: 64  DRPPKKPRHGGFILDEADVDDEYEDEDQWEDGAEDILEKEEIEA 107



 Score = 35.4 bits (80), Expect = 0.010
 Identities = 24/100 (24%), Positives = 44/100 (44%), Gaps = 12/100 (12%)

Query: 3   EKSVEAAAELSAKDLKEKKEKVEEKASRKERKKEVVEEEENGAEEEEEETAEDG------ 56
           E+  E +++    ++ E++         +E + E  EEEE   +EEEEE  +D       
Sbjct: 12  EEDSERSSDGEEAEVDEERRSAAGSEKEEEPEDEEEEEEEEEYDEEEEEEDDDRPPKKPR 71

Query: 57  ------EEEDEGEEEDEEEEEEDDEGPALKRAAEEEDEAD 90
                 +E D  +E ++E++ ED     L++   E    D
Sbjct: 72  HGGFILDEADVDDEYEDEDQWEDGAEDILEKEEIEASNID 111



 Score = 29.6 bits (65), Expect = 0.53
 Identities = 24/78 (30%), Positives = 39/78 (50%), Gaps = 6/78 (7%)

Query: 2   SEKSVEAAAELSAKDLKEKKEKVEEKASRKERKKE-----VVEEEENGAEEEEEETAEDG 56
           SEK  E   E   ++ +E  E+ EE+   +  KK      +++E +   E E+E+  EDG
Sbjct: 36  SEKEEEPEDEEEEEEEEEYDEEEEEEDDDRPPKKPRHGGFILDEADVDDEYEDEDQWEDG 95

Query: 57  EEEDEGEEEDEEEEEEDD 74
            E D  E+E+ E    D+
Sbjct: 96  AE-DILEKEEIEASNIDN 112


>gi|84043963 eukaryotic translation initiation factor 5B [Homo
           sapiens]
          Length = 1220

 Score = 56.6 bits (135), Expect = 4e-09
 Identities = 35/91 (38%), Positives = 51/91 (56%), Gaps = 12/91 (13%)

Query: 19  EKKEKVEEKASRKERKKEVVEEEENGAEEEEEETAEDGEEED------EGEEEDEEEEEE 72
           E+ EKVE      E K+   EEEE   EEEE+E +E+ EEE+      EG+EEDE+  +E
Sbjct: 513 EETEKVEGNKVHIEVKENPEEEEEEEEEEEEDEESEEEEEEEGESEGSEGDEEDEKVSDE 572

Query: 73  DDEG------PALKRAAEEEDEADPKRQKTE 97
            D G      P+ + +++ E ++D  R K E
Sbjct: 573 KDSGKTLDKKPSKEMSSDSEYDSDDDRTKEE 603



 Score = 48.9 bits (115), Expect = 9e-07
 Identities = 28/68 (41%), Positives = 39/68 (57%), Gaps = 6/68 (8%)

Query: 25  EEKASRKERKKEVVEEEENGAEEEEEETAEDGEEEDEGEEEDEEEEEEDDEGPALKRAAE 84
           +E+  + E  K  +E +EN  EEEEE      EEE+E +EE EEEEEE+ E    +   E
Sbjct: 512 DEETEKVEGNKVHIEVKENPEEEEEE------EEEEEEDEESEEEEEEEGESEGSEGDEE 565

Query: 85  EEDEADPK 92
           +E  +D K
Sbjct: 566 DEKVSDEK 573



 Score = 42.4 bits (98), Expect = 8e-05
 Identities = 28/98 (28%), Positives = 51/98 (52%), Gaps = 2/98 (2%)

Query: 2   SEKSVEA--AAELSAKDLKEKKEKVEEKASRKERKKEVVEEEENGAEEEEEETAEDGEEE 59
           SE+  E   AAE   +  K+KK+K ++K  ++E++KE  +       +  +E     +EE
Sbjct: 295 SEEKAETPTAAEDDNEGDKKKKDKKKKKGEKEEKEKEKKKGPSKATVKAMQEALAKLKEE 354

Query: 60  DEGEEEDEEEEEEDDEGPALKRAAEEEDEADPKRQKTE 97
           +E ++ +EEE  +  E    KR  EE  E + + +K +
Sbjct: 355 EERQKREEEERIKRLEELEAKRKEEERLEQEKRERKKQ 392



 Score = 42.0 bits (97), Expect = 1e-04
 Identities = 32/97 (32%), Positives = 49/97 (50%), Gaps = 16/97 (16%)

Query: 8   AAAELSAKDLKEKKEKVEEKASRKERKKEV--VEEEENGAEEEEEETAE----------- 54
           AA E+  + + EK+E        +E   E   +++ E  A +EE E  E           
Sbjct: 471 AAVEVMEQGVPEKEETPPPVEPEEEEDTEDAGLDDWEAMASDEETEKVEGNKVHIEVKEN 530

Query: 55  -DGEEEDEGEEEDEE--EEEEDDEGPALKRAAEEEDE 88
            + EEE+E EEE++E  EEEE++EG +     +EEDE
Sbjct: 531 PEEEEEEEEEEEEDEESEEEEEEEGESEGSEGDEEDE 567



 Score = 39.3 bits (90), Expect = 7e-04
 Identities = 27/84 (32%), Positives = 45/84 (53%), Gaps = 6/84 (7%)

Query: 2   SEKSVEAAAELSAKDLKEKKEKVEEKASRKERKKEVVEEEENGAEEEEEETAEDGEEEDE 61
           S+ +V+A  E  AK LKE     EE+  ++E ++ +   EE  A+ +EEE  E  + E +
Sbjct: 337 SKATVKAMQEALAK-LKE-----EEERQKREEEERIKRLEELEAKRKEEERLEQEKRERK 390

Query: 62  GEEEDEEEEEEDDEGPALKRAAEE 85
            ++E E +E    EG  L ++  E
Sbjct: 391 KQKEKERKERLKKEGKLLTKSQRE 414



 Score = 37.7 bits (86), Expect = 0.002
 Identities = 30/105 (28%), Positives = 49/105 (46%), Gaps = 18/105 (17%)

Query: 11  ELSAKDLKEKKEKVEEKASRKERKKEVVEEEENGAEEEEEETAEDGEEEDEGEE------ 64
           E   KD  ++KE   +      + K  V+     A EE+ ET    E+++EG++      
Sbjct: 260 ETGKKDQSKQKESQRKFEEETVKSKVTVDTGVIPASEEKAETPTAAEDDNEGDKKKKDKK 319

Query: 65  ----EDEEEEEEDDEGP--ALKRAAEE------EDEADPKRQKTE 97
               E EE+E+E  +GP  A  +A +E      E+E   KR++ E
Sbjct: 320 KKKGEKEEKEKEKKKGPSKATVKAMQEALAKLKEEEERQKREEEE 364



 Score = 37.0 bits (84), Expect = 0.003
 Identities = 22/81 (27%), Positives = 42/81 (51%)

Query: 15  KDLKEKKEKVEEKASRKERKKEVVEEEENGAEEEEEETAEDGEEEDEGEEEDEEEEEEDD 74
           K  K+KK+K  EK  +++ KK+   +    A +E     ++ EE  + EEE+  +  E+ 
Sbjct: 313 KKKKDKKKKKGEKEEKEKEKKKGPSKATVKAMQEALAKLKEEEERQKREEEERIKRLEEL 372

Query: 75  EGPALKRAAEEEDEADPKRQK 95
           E    +    E+++ + K+QK
Sbjct: 373 EAKRKEEERLEQEKRERKKQK 393



 Score = 37.0 bits (84), Expect = 0.003
 Identities = 26/85 (30%), Positives = 43/85 (50%), Gaps = 1/85 (1%)

Query: 15  KDLKEKKEKVEEKASRKERKKEVVEEEENGAEEEEEETAEDGEEEDEGEEEDEEEEEEDD 74
           K  KE+KEK ++K   K   K + E      EEEE +  E+ EE  +  EE E + +E++
Sbjct: 322 KGEKEEKEKEKKKGPSKATVKAMQEALAKLKEEEERQKREE-EERIKRLEELEAKRKEEE 380

Query: 75  EGPALKRAAEEEDEADPKRQKTENG 99
                KR  +++ E + K +  + G
Sbjct: 381 RLEQEKRERKKQKEKERKERLKKEG 405



 Score = 34.7 bits (78), Expect = 0.017
 Identities = 22/91 (24%), Positives = 47/91 (51%), Gaps = 17/91 (18%)

Query: 21  KEKVEEKASRKERKKEVVEEEENGAEE-EEEETAEDGEEEDEGEEEDEEEEEED------ 73
           K   ++KA +KER+++  +EE+    + +E+E  E G+++   ++E + + EE+      
Sbjct: 226 KTVAQKKAEKKERERKKRDEEKAKLRKLKEKEELETGKKDQSKQKESQRKFEEETVKSKV 285

Query: 74  ----------DEGPALKRAAEEEDEADPKRQ 94
                     +E      AAE+++E D K++
Sbjct: 286 TVDTGVIPASEEKAETPTAAEDDNEGDKKKK 316



 Score = 34.7 bits (78), Expect = 0.017
 Identities = 27/85 (31%), Positives = 37/85 (43%), Gaps = 5/85 (5%)

Query: 11  ELSAKDLKEKKEKVEEKASRKE-----RKKEVVEEEENGAEEEEEETAEDGEEEDEGEEE 65
           E+ +KD   KK  + E   RK+       KEV E  E  A  E  E     +EE     E
Sbjct: 432 EVPSKDSLPKKRPIYEDKKRKKIPQQLESKEVSESMELCAAVEVMEQGVPEKEETPPPVE 491

Query: 66  DEEEEEEDDEGPALKRAAEEEDEAD 90
            EEEE+ +D G     A   ++E +
Sbjct: 492 PEEEEDTEDAGLDDWEAMASDEETE 516



 Score = 33.9 bits (76), Expect = 0.028
 Identities = 32/119 (26%), Positives = 59/119 (49%), Gaps = 19/119 (15%)

Query: 2   SEKSVEAAAELSAKDLKEKKEKVEEKAS-RKERKKEVVE-------EEENGAEEEEEETA 53
           S K    A + + K  +E+K++ EEKA  RK ++KE +E       +++    + EEET 
Sbjct: 222 SFKIKTVAQKKAEKKERERKKRDEEKAKLRKLKEKEELETGKKDQSKQKESQRKFEEETV 281

Query: 54  EDGEEEDEGEEEDEEEE-------EEDDEGPALKRAAE----EEDEADPKRQKTENGAS 101
           +     D G     EE+       E+D+EG   K+  +    E++E + +++K  + A+
Sbjct: 282 KSKVTVDTGVIPASEEKAETPTAAEDDNEGDKKKKDKKKKKGEKEEKEKEKKKGPSKAT 340



 Score = 33.1 bits (74), Expect = 0.048
 Identities = 22/102 (21%), Positives = 49/102 (48%), Gaps = 22/102 (21%)

Query: 11  ELSAKDLKEK-------------KEKVEEKASRKERKKEVVEEEENGAEEEEEET----- 52
           E ++KD K+K              E++E+K S+ ++  +   E  +G++++++       
Sbjct: 90  EFTSKDKKKKGQKGKKQSFDDNDSEELEDKDSKSKKTAKPKVEMYSGSDDDDDFNKLPKK 149

Query: 53  ----AEDGEEEDEGEEEDEEEEEEDDEGPALKRAAEEEDEAD 90
               A+   ++ +G EEDE+  ++  E   +  + E  DE+D
Sbjct: 150 AKGKAQKSNKKWDGSEEDEDNSKKIKERSRINSSGESGDESD 191



 Score = 30.8 bits (68), Expect = 0.24
 Identities = 15/75 (20%), Positives = 38/75 (50%)

Query: 27  KASRKERKKEVVEEEENGAEEEEEETAEDGEEEDEGEEEDEEEEEEDDEGPALKRAAEEE 86
           K  +K +K +     E+G E+++         + + E+++ E ++ D+E   L++  E+E
Sbjct: 198 KGQKKNQKNKPGPNIESGNEDDDASFKIKTVAQKKAEKKERERKKRDEEKAKLRKLKEKE 257

Query: 87  DEADPKRQKTENGAS 101
           +    K+ +++   S
Sbjct: 258 ELETGKKDQSKQKES 272



 Score = 30.0 bits (66), Expect = 0.41
 Identities = 26/104 (25%), Positives = 48/104 (46%), Gaps = 16/104 (15%)

Query: 9   AAELSAKDLKEKKEKVEEKASR-KERKKEVVEEEENGAEEEEEETAEDGEEED------- 60
           AAE+      +++E  + K  + KE+KK+  +E++   E EE      G + D       
Sbjct: 23  AAEIEGAGAAKEQEPQKSKGKKKKEKKKQDFDEDDILKELEELSLEAQGIKADRETVAVK 82

Query: 61  --EGEEEDEEEEEEDDEGPALKRA------AEEEDEADPKRQKT 96
             E  EE+   +++  +G   K+       +EE ++ D K +KT
Sbjct: 83  PTENNEEEFTSKDKKKKGQKGKKQSFDDNDSEELEDKDSKSKKT 126



 Score = 28.9 bits (63), Expect = 0.91
 Identities = 24/101 (23%), Positives = 48/101 (47%), Gaps = 18/101 (17%)

Query: 2   SEKSVEAAAEL-SAKDLKEKKEKVEEKASRKERKKEVVEEEENGAEEEEEETAEDGEEE- 59
           S+K+ +   E+ S  D  +   K+ +KA  K +K     ++ +G+EE+E+ + +  E   
Sbjct: 123 SKKTAKPKVEMYSGSDDDDDFNKLPKKAKGKAQKSN---KKWDGSEEDEDNSKKIKERSR 179

Query: 60  --DEGEEEDEEEE-----------EEDDEGPALKRAAEEED 87
               GE  DE +E           +++  GP ++   E++D
Sbjct: 180 INSSGESGDESDEFLQSRKGQKKNQKNKPGPNIESGNEDDD 220


>gi|28274705 family with sequence similarity 9, member A [Homo
           sapiens]
          Length = 332

 Score = 56.6 bits (135), Expect = 4e-09
 Identities = 30/67 (44%), Positives = 43/67 (64%)

Query: 9   AAELSAKDLKEKKEKVEEKASRKERKKEVVEEEENGAEEEEEETAEDGEEEDEGEEEDEE 68
           AA  +A+ +  + E+ EEK   +E+++E  E EE G  EE EE    GE E+  EEE+EE
Sbjct: 209 AAAAAAEVIVVEDEEEEEKEEEEEKEEEEEEGEEEGGGEEGEEGGGGGEGEETEEEEEEE 268

Query: 69  EEEEDDE 75
           EEEE++E
Sbjct: 269 EEEEEEE 275



 Score = 55.8 bits (133), Expect = 7e-09
 Identities = 32/70 (45%), Positives = 46/70 (65%), Gaps = 2/70 (2%)

Query: 4   KSVEAAAELSAKDLKEKKEKVEEKASRKERKKEVVEEEENGAEEEEEETAEDGEEEDEGE 63
           ++  AAAE+   + +E++EK EE+   KE ++E  EEE  G E EE     +GEE +E E
Sbjct: 208 EAAAAAAEVIVVEDEEEEEKEEEE--EKEEEEEEGEEEGGGEEGEEGGGGGEGEETEEEE 265

Query: 64  EEDEEEEEED 73
           EE+EEEEEE+
Sbjct: 266 EEEEEEEEEE 275



 Score = 53.5 bits (127), Expect = 3e-08
 Identities = 37/92 (40%), Positives = 50/92 (54%), Gaps = 7/92 (7%)

Query: 5   SVEAAAELSAKDLKEKKEKVE-EKASRKERKKEVVEEEENGAEEEEEETAEDGEEEDEGE 63
           + EAAA   A     +   VE E+   KE ++E  EEEE G EE   E  E+G    EGE
Sbjct: 200 AAEAAAAAEAAAAAAEVIVVEDEEEEEKEEEEEKEEEEEEGEEEGGGEEGEEGGGGGEGE 259

Query: 64  EEDEEEEEEDDEGPALKRAAEEEDEADPKRQK 95
           E +EEEEEE++E        EE+ +A  ++QK
Sbjct: 260 ETEEEEEEEEEE------EEEEQIKAFQEKQK 285



 Score = 50.1 bits (118), Expect = 4e-07
 Identities = 33/97 (34%), Positives = 50/97 (51%), Gaps = 3/97 (3%)

Query: 1   MSEKSVEAAAELSAKDLKEKKEKVEEKASRKERKKEVVEEEENGAEEEEEETAEDGEEED 60
           ++EK  +  AE +       +     +A+    +  VVE+EE   EEE+EE  E  EEE+
Sbjct: 182 IAEKQKDDEAEEAEAAAAAAEAAAAAEAAAAAAEVIVVEDEE---EEEKEEEEEKEEEEE 238

Query: 61  EGEEEDEEEEEEDDEGPALKRAAEEEDEADPKRQKTE 97
           EGEEE   EE E+  G       EEE+E + + ++ E
Sbjct: 239 EGEEEGGGEEGEEGGGGGEGEETEEEEEEEEEEEEEE 275



 Score = 48.1 bits (113), Expect = 1e-06
 Identities = 33/92 (35%), Positives = 44/92 (47%), Gaps = 8/92 (8%)

Query: 3   EKSVEAAAELSAKDLKEKKEKVEEKASRKERKKEVVEEEENGAEEEEEETAEDGEEEDEG 62
           E    AAA  +A   +      E      E ++E  EEEE   EEEE E    GEE +EG
Sbjct: 193 EAEAAAAAAEAAAAAEAAAAAAEVIVVEDEEEEEKEEEEEKEEEEEEGEEEGGGEEGEEG 252

Query: 63  --------EEEDEEEEEEDDEGPALKRAAEEE 86
                    EE+EEEEEE++E   +K   E++
Sbjct: 253 GGGGEGEETEEEEEEEEEEEEEEQIKAFQEKQ 284



 Score = 45.4 bits (106), Expect = 9e-06
 Identities = 29/88 (32%), Positives = 41/88 (46%)

Query: 7   EAAAELSAKDLKEKKEKVEEKASRKERKKEVVEEEENGAEEEEEETAEDGEEEDEGEEED 66
           + A E  A     +     E A+       V +EEE   EEEEE+  E+ E E+EG  E+
Sbjct: 189 DEAEEAEAAAAAAEAAAAAEAAAAAAEVIVVEDEEEEEKEEEEEKEEEEEEGEEEGGGEE 248

Query: 67  EEEEEEDDEGPALKRAAEEEDEADPKRQ 94
            EE     EG   +   EEE+E + + Q
Sbjct: 249 GEEGGGGGEGEETEEEEEEEEEEEEEEQ 276



 Score = 42.7 bits (99), Expect = 6e-05
 Identities = 31/103 (30%), Positives = 48/103 (46%), Gaps = 7/103 (6%)

Query: 2   SEKSVEAAAELSAKDLKEKKEKVEEKASRKERKKEVVEEEENGAE----EEEEETAEDGE 57
           + K +    E  A+  K+ + +  E A+         E     AE    E+EEE  ++ E
Sbjct: 171 TRKLLNVLKEYIAEKQKDDEAEEAEAAAAAAEAAAAAEAAAAAAEVIVVEDEEEEEKEEE 230

Query: 58  EEDEGEEEDEEEE---EEDDEGPALKRAAEEEDEADPKRQKTE 97
           EE E EEE+ EEE   EE +EG       E E+E + + ++ E
Sbjct: 231 EEKEEEEEEGEEEGGGEEGEEGGGGGEGEETEEEEEEEEEEEE 273



 Score = 34.7 bits (78), Expect = 0.017
 Identities = 30/98 (30%), Positives = 44/98 (44%), Gaps = 16/98 (16%)

Query: 17  LKEKKEKVEEKASRKERK-----KEVVEEEENGAEEEEEETAEDGEEEDEGEEE------ 65
           LK+K+ K +++  R  RK     KE + E++   E EE E A    E     E       
Sbjct: 156 LKKKQLKRQKRDYRHTRKLLNVLKEYIAEKQKDDEAEEAEAAAAAAEAAAAAEAAAAAAE 215

Query: 66  ----DEEEEEEDDEGPALKRAAEEEDEADPKRQKTENG 99
               ++EEEEE +E    K   EEE E +   ++ E G
Sbjct: 216 VIVVEDEEEEEKEEEEE-KEEEEEEGEEEGGGEEGEEG 252


>gi|239050813 lipoxygenase homology domains 1 isoform 1 [Homo
           sapiens]
          Length = 2211

 Score = 56.2 bits (134), Expect = 5e-09
 Identities = 32/90 (35%), Positives = 50/90 (55%), Gaps = 12/90 (13%)

Query: 4   KSVEAAAELSAKDLKEK--------KEKVEEKASRKERKKEVVEEEENGAEEEEEETAED 55
           + V+   E  A+  KEK        KE+++ K  RK++K++  +EE+ G EEE   + E 
Sbjct: 904 REVDLTPEEEARKKKEKDKLRQLLKKERLKAKLQRKKKKRKGSDEEDEGEEEESSSSEES 963

Query: 56  GEEEDEGEEEDEEEEEEDDEGPALKRAAEE 85
             EE+E EEE+EEEE     GP ++   E+
Sbjct: 964 SSEEEEMEEEEEEEE----FGPGMQEVIEQ 989



 Score = 41.2 bits (95), Expect = 2e-04
 Identities = 23/85 (27%), Positives = 43/85 (50%), Gaps = 1/85 (1%)

Query: 12  LSAKDLKEKKEKVEEKASRKERKKEVVEEEENGAEEEEEETAEDG-EEEDEGEEEDEEEE 70
           L  +++    E+   K   K++ ++++++E   A+ + ++    G +EEDEGEEE+    
Sbjct: 901 LVVREVDLTPEEEARKKKEKDKLRQLLKKERLKAKLQRKKKKRKGSDEEDEGEEEESSSS 960

Query: 71  EEDDEGPALKRAAEEEDEADPKRQK 95
           EE           EEE+E  P  Q+
Sbjct: 961 EESSSEEEEMEEEEEEEEFGPGMQE 985


>gi|4504425 high-mobility group box 1 [Homo sapiens]
          Length = 215

 Score = 55.8 bits (133), Expect = 7e-09
 Identities = 31/69 (44%), Positives = 43/69 (62%), Gaps = 4/69 (5%)

Query: 11  ELSAKDLKEKKEK----VEEKASRKERKKEVVEEEENGAEEEEEETAEDGEEEDEGEEED 66
           E  A  LKEK EK       K      KK VV+ E++  ++EEEE  ED E+E+E E+E+
Sbjct: 145 EKKAAKLKEKYEKDIAAYRAKGKPDAAKKGVVKAEKSKKKKEEEEDEEDEEDEEEEEDEE 204

Query: 67  EEEEEEDDE 75
           +E+EEEDD+
Sbjct: 205 DEDEEEDDD 213



 Score = 49.3 bits (116), Expect = 7e-07
 Identities = 28/70 (40%), Positives = 42/70 (60%), Gaps = 5/70 (7%)

Query: 1   MSEKSVEAAAELSAKDLKEKKEKVEEKASRKERKKEVVEEEENGAEEEEEETAEDGEEED 60
           + EK  +  A   AK   +  +K   KA + ++KKE  E+EE+  +EEEEE     +EED
Sbjct: 151 LKEKYEKDIAAYRAKGKPDAAKKGVVKAEKSKKKKEEEEDEEDEEDEEEEE-----DEED 205

Query: 61  EGEEEDEEEE 70
           E EEED+++E
Sbjct: 206 EDEEEDDDDE 215



 Score = 48.5 bits (114), Expect = 1e-06
 Identities = 27/71 (38%), Positives = 41/71 (57%), Gaps = 5/71 (7%)

Query: 3   EKSVEAAAELSAKDLKEKKEKVEEKASRK-----ERKKEVVEEEENGAEEEEEETAEDGE 57
           EK      E   KD+   + K +  A++K     E+ K+  EEEE+  +EE+EE  ED E
Sbjct: 145 EKKAAKLKEKYEKDIAAYRAKGKPDAAKKGVVKAEKSKKKKEEEEDEEDEEDEEEEEDEE 204

Query: 58  EEDEGEEEDEE 68
           +EDE E++D+E
Sbjct: 205 DEDEEEDDDDE 215



 Score = 37.4 bits (85), Expect = 0.003
 Identities = 23/86 (26%), Positives = 41/86 (47%), Gaps = 8/86 (9%)

Query: 13  SAKDLKEKKEKVEEKASRKERKKEVVEEEENGAEEEEEETAEDGEEEDEGEEEDEEEEEE 72
           +A D K+  EK   K   K  K       +   +  ++   +  + + + EEE++EE+EE
Sbjct: 136 TAADDKQPYEKKAAKLKEKYEKDIAAYRAKGKPDAAKKGVVKAEKSKKKKEEEEDEEDEE 195

Query: 73  DDEGPALKRAAEEEDEADPKRQKTEN 98
           D+E        EEEDE D   ++ ++
Sbjct: 196 DEE--------EEEDEEDEDEEEDDD 213



 Score = 30.4 bits (67), Expect = 0.31
 Identities = 19/81 (23%), Positives = 42/81 (51%), Gaps = 6/81 (7%)

Query: 19  EKKEKVEEKASRKERK--KEVVEEEENGAEEEEEETAEDGEEEDEGEEEDEEEEEEDDEG 76
           + K+  E+KA++ + K  K++      G    + + A+ G  + E  ++ +EEEE++++ 
Sbjct: 139 DDKQPYEKKAAKLKEKYEKDIAAYRAKG----KPDAAKKGVVKAEKSKKKKEEEEDEEDE 194

Query: 77  PALKRAAEEEDEADPKRQKTE 97
              +   +EEDE + +    E
Sbjct: 195 EDEEEEEDEEDEDEEEDDDDE 215


>gi|66792814 retrotransposon gag domain containing 4 [Homo sapiens]
          Length = 569

 Score = 55.8 bits (133), Expect = 7e-09
 Identities = 29/82 (35%), Positives = 50/82 (60%), Gaps = 5/82 (6%)

Query: 15  KDLKEKKEKVEEKASRKERKKEVVEEEENGAEEEEEETAEDGEEEDEGEEEDEEEEEEDD 74
           +++KEK+E+  +K    ++K+E  EEEE   +++EEE     + E+EGE +DEE+E+ED 
Sbjct: 371 QEMKEKEEEEMKKEEEMKKKEEKEEEEEEEMKQKEEEEEIRNKNEEEGESKDEEDEDEDG 430

Query: 75  EGPALKRAAEEEDEADPKRQKT 96
                 +  E E + DP  ++T
Sbjct: 431 -----GQKPEGEPQQDPGTEET 447



 Score = 47.8 bits (112), Expect = 2e-06
 Identities = 24/85 (28%), Positives = 49/85 (57%), Gaps = 2/85 (2%)

Query: 15  KDLKEKKEKVEEKASRKERKKEVVEEEENGAEEEEEETAEDGEEEDEGEEEDEEEEEEDD 74
           +D + ++ ++  K  RK  +    ++E    EEEE +  E+ ++++E EEE+EEE ++ +
Sbjct: 348 EDQEARRHRLHSKDQRKRMR--AFQQEMKEKEEEEMKKEEEMKKKEEKEEEEEEEMKQKE 405

Query: 75  EGPALKRAAEEEDEADPKRQKTENG 99
           E   ++   EEE E+  +  + E+G
Sbjct: 406 EEEEIRNKNEEEGESKDEEDEDEDG 430



 Score = 46.2 bits (108), Expect = 6e-06
 Identities = 27/74 (36%), Positives = 43/74 (58%), Gaps = 2/74 (2%)

Query: 1   MSEKSVEAAA-ELSAKDLKEKKEKVEEKASRKERKKEV-VEEEENGAEEEEEETAEDGEE 58
           M EK  E    E   K  +EK+E+ EE+  +KE ++E+  + EE G  ++EE+  EDG +
Sbjct: 373 MKEKEEEEMKKEEEMKKKEEKEEEEEEEMKQKEEEEEIRNKNEEEGESKDEEDEDEDGGQ 432

Query: 59  EDEGEEEDEEEEEE 72
           + EGE + +   EE
Sbjct: 433 KPEGEPQQDPGTEE 446



 Score = 45.8 bits (107), Expect = 7e-06
 Identities = 27/88 (30%), Positives = 44/88 (50%)

Query: 3   EKSVEAAAELSAKDLKEKKEKVEEKASRKERKKEVVEEEENGAEEEEEETAEDGEEEDEG 62
           ++ ++   E   K  +E K+K E++   +E  K+  EEEE   + EEE  ++D E+EDE 
Sbjct: 370 QQEMKEKEEEEMKKEEEMKKKEEKEEEEEEEMKQKEEEEEIRNKNEEEGESKDEEDEDED 429

Query: 63  EEEDEEEEEEDDEGPALKRAAEEEDEAD 90
             +  E E + D G        EE+  D
Sbjct: 430 GGQKPEGEPQQDPGTEETYGEVEEEPLD 457



 Score = 44.3 bits (103), Expect = 2e-05
 Identities = 29/88 (32%), Positives = 49/88 (55%), Gaps = 11/88 (12%)

Query: 12  LSAKDLKEKKEKVEEKASRKERKKEVVEEEENGAEEEEEETAEDGEEEDEGEEEDEEE-- 69
           L +KD +++    +++   KE ++   EEE    EE+EEE     EEE+  ++E+EEE  
Sbjct: 357 LHSKDQRKRMRAFQQEMKEKEEEEMKKEEEMKKKEEKEEE-----EEEEMKQKEEEEEIR 411

Query: 70  EEEDDEGPALKRAAEEEDEADPKRQKTE 97
            + ++EG     + +EEDE +   QK E
Sbjct: 412 NKNEEEG----ESKDEEDEDEDGGQKPE 435



 Score = 42.4 bits (98), Expect = 8e-05
 Identities = 23/76 (30%), Positives = 40/76 (52%), Gaps = 1/76 (1%)

Query: 1   MSEKSVEAAAELSAKDLKEKKEKVEEKASRKERKKEVVEEEENGAEEEEEETAED-GEEE 59
           M +K  +   E      KE++E++  K   +   K+  +E+E+G ++ E E  +D G EE
Sbjct: 387 MKKKEEKEEEEEEEMKQKEEEEEIRNKNEEEGESKDEEDEDEDGGQKPEGEPQQDPGTEE 446

Query: 60  DEGEEEDEEEEEEDDE 75
             GE E+E  +E  D+
Sbjct: 447 TYGEVEEEPLDEAQDD 462



 Score = 30.8 bits (68), Expect = 0.24
 Identities = 21/91 (23%), Positives = 48/91 (52%), Gaps = 8/91 (8%)

Query: 11  ELSAKDLKEKKEKVEEKASRKERKKEVVEEEENGAEEEEEETAEDGEEEDEGEEEDE--- 67
           E  ++D +   E  +++A R     +   +     ++E +E     +EE+E ++E+E   
Sbjct: 335 EEESEDEEYYSEDEDQEARRHRLHSKDQRKRMRAFQQEMKE-----KEEEEMKKEEEMKK 389

Query: 68  EEEEEDDEGPALKRAAEEEDEADPKRQKTEN 98
           +EE+E++E   +K+  EEE+  +   ++ E+
Sbjct: 390 KEEKEEEEEEEMKQKEEEEEIRNKNEEEGES 420


>gi|21735415 centromere protein B [Homo sapiens]
          Length = 599

 Score = 55.5 bits (132), Expect = 9e-09
 Identities = 31/72 (43%), Positives = 44/72 (61%), Gaps = 5/72 (6%)

Query: 19  EKKEKVEEKASRKERKKEVVEEEENGAEEEE-----EETAEDGEEEDEGEEEDEEEEEED 73
           E +E+ EE+   +E + E  EEEE G EEEE     EE  E+ E E+EG+ + +EEEEED
Sbjct: 404 EGEEEEEEEEEEEEEEGEGEEEEEEGEEEEEEGGEGEELGEEEEVEEEGDVDSDEEEEED 463

Query: 74  DEGPALKRAAEE 85
           +E  +    AE+
Sbjct: 464 EESSSEGLEAED 475



 Score = 53.9 bits (128), Expect = 3e-08
 Identities = 31/59 (52%), Positives = 35/59 (59%), Gaps = 9/59 (15%)

Query: 39  EEEENGAEEEEEETAEDGEEEDEGEEEDE---------EEEEEDDEGPALKRAAEEEDE 88
           EEEE   EEEEEE  E  EEE+EGEEE+E         EEEE ++EG       EEEDE
Sbjct: 406 EEEEEEEEEEEEEEGEGEEEEEEGEEEEEEGGEGEELGEEEEVEEEGDVDSDEEEEEDE 464



 Score = 50.8 bits (120), Expect = 2e-07
 Identities = 30/58 (51%), Positives = 33/58 (56%), Gaps = 3/58 (5%)

Query: 40  EEENGAEEEEEETAEDGEEEDEGEEEDEEEEEEDDEGPALKRAAEEEDEADPKRQKTE 97
           EEE   EEEEEE   +GEEE   EEE EEEEEE  EG  L    E E+E D    + E
Sbjct: 406 EEEEEEEEEEEEEEGEGEEE---EEEGEEEEEEGGEGEELGEEEEVEEEGDVDSDEEE 460



 Score = 50.1 bits (118), Expect = 4e-07
 Identities = 33/75 (44%), Positives = 44/75 (58%), Gaps = 15/75 (20%)

Query: 34  KKEVVEEEENGAEEEEEETAEDGEEEDEGEEEDEEEEEEDDEGPALKRAAEEED------ 87
           K E  EEEE   EEEEEE     EEE EGEEE+EE EEE++EG   +   EEE+      
Sbjct: 402 KSEGEEEEE---EEEEEE-----EEEGEGEEEEEEGEEEEEEGGEGEELGEEEEVEEEGD 453

Query: 88  -EADPKRQKTENGAS 101
            ++D + ++ E  +S
Sbjct: 454 VDSDEEEEEDEESSS 468



 Score = 40.0 bits (92), Expect = 4e-04
 Identities = 15/36 (41%), Positives = 25/36 (69%)

Query: 42  ENGAEEEEEETAEDGEEEDEGEEEDEEEEEEDDEGP 77
           E G + + +   ED EEED+ +E+D+++EE+ DE P
Sbjct: 505 EGGEDSDSDSEEEDDEEEDDEDEDDDDDEEDGDEVP 540



 Score = 39.3 bits (90), Expect = 7e-04
 Identities = 26/97 (26%), Positives = 42/97 (43%)

Query: 3   EKSVEAAAELSAKDLKEKKEKVEEKASRKERKKEVVEEEENGAEEEEEETAEDGEEEDEG 62
           E+  E   E   ++ +E+ E+ EE+    E   E  E EE G  + +EE  ED E   EG
Sbjct: 411 EEEEEEEEEGEGEEEEEEGEEEEEEGGEGEELGEEEEVEEEGDVDSDEEEEEDEESSSEG 470

Query: 63  EEEDEEEEEEDDEGPALKRAAEEEDEADPKRQKTENG 99
            E ++  +   + G +      +E+   P     E G
Sbjct: 471 LEAEDWAQGVVEAGGSFGAYGAQEEAQCPTLHFLEGG 507



 Score = 35.4 bits (80), Expect = 0.010
 Identities = 35/129 (27%), Positives = 49/129 (37%), Gaps = 58/129 (44%)

Query: 18  KEKKEKVEEKASRKERKKEVVEEEENGAEEEE----EETAEDG-----EEEDEGEE---- 64
           +E++E+ EE+   +E ++E  EEEE G E EE    EE  E+G     EEE+E EE    
Sbjct: 410 EEEEEEEEEEGEGEEEEEEGEEEEEEGGEGEELGEEEEVEEEGDVDSDEEEEEDEESSSE 469

Query: 65  ---------------------------------------------EDEEEEEEDDEGPAL 79
                                                        E+E++EEEDDE    
Sbjct: 470 GLEAEDWAQGVVEAGGSFGAYGAQEEAQCPTLHFLEGGEDSDSDSEEEDDEEEDDEDEDD 529

Query: 80  KRAAEEEDE 88
               E+ DE
Sbjct: 530 DDDEEDGDE 538



 Score = 35.0 bits (79), Expect = 0.013
 Identities = 14/41 (34%), Positives = 27/41 (65%)

Query: 39  EEEENGAEEEEEETAEDGEEEDEGEEEDEEEEEEDDEGPAL 79
           E+ ++ +EEE++E  +D +E+D+ +EED +E      G A+
Sbjct: 508 EDSDSDSEEEDDEEEDDEDEDDDDDEEDGDEVPVPSFGEAM 548



 Score = 34.3 bits (77), Expect = 0.022
 Identities = 19/37 (51%), Positives = 24/37 (64%), Gaps = 1/37 (2%)

Query: 52  TAEDGEEEDEGEEEDEEEEEEDDEGPALKRAAEEEDE 88
           T+   E E+E EEE+EEEEEE  EG   +   EEE+E
Sbjct: 399 TSLKSEGEEEEEEEEEEEEEE-GEGEEEEEEGEEEEE 434


>gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens]
          Length = 1020

 Score = 55.5 bits (132), Expect = 9e-09
 Identities = 36/89 (40%), Positives = 51/89 (57%), Gaps = 11/89 (12%)

Query: 19  EKKEK----VEEKASRKERKKEVVEEEENGAEEEEEETAEDGEEEDEGEEEDEEEEEEDD 74
           EK EK    VEE+    +  +EV EEEE  A+EEE      G+EE+ GEEE+ E  EE+ 
Sbjct: 448 EKSEKETVIVEEQTEETQVTEEVTEEEEKEAKEEE------GKEEEGGEEEEAEGGEEET 501

Query: 75  EGPALKRAAEEEDEA-DPKRQKTENGASA 102
           + P  + AA  E EA  P +++ ++ A A
Sbjct: 502 KSPPAEEAASPEKEAKSPVKEEAKSPAEA 530



 Score = 43.5 bits (101), Expect = 4e-05
 Identities = 29/117 (24%), Positives = 57/117 (48%), Gaps = 18/117 (15%)

Query: 3   EKSVEAAAELSAKDLKEKKE------------KVEEKASRKERKKEVVEEEENGAEEEEE 50
           EK  E+  E   ++ ++KK+            +V+E A  KE+ +   +E ++   +E  
Sbjct: 883 EKPKESKVEAKKEEAEDKKKVPTPEKEAPAKVEVKEDAKPKEKTEVAKKEPDDAKAKEPS 942

Query: 51  ETAEDGEEEDEGEEEDEEEEEEDDEGPALKRAAEEEDE------ADPKRQKTENGAS 101
           + AE  E   E ++  EE+ ++ +E P  +  A+E+D+      + PK +K E  +S
Sbjct: 943 KPAEKKEAAPEKKDTKEEKAKKPEEKPKTEAKAKEDDKTLSKEPSKPKAEKAEKSSS 999



 Score = 42.7 bits (99), Expect = 6e-05
 Identities = 25/85 (29%), Positives = 43/85 (50%)

Query: 18  KEKKEKVEEKASRKERKKEVVEEEENGAEEEEEETAEDGEEEDEGEEEDEEEEEEDDEGP 77
           +E  E+ E++A  +E K+E   EEE     EEE  +   EE    E+E +   +E+ + P
Sbjct: 468 EEVTEEEEKEAKEEEGKEEEGGEEEEAEGGEEETKSPPAEEAASPEKEAKSPVKEEAKSP 527

Query: 78  ALKRAAEEEDEADPKRQKTENGASA 102
           A  ++ E+E+   P   K+   A +
Sbjct: 528 AEAKSPEKEEAKSPAEVKSPEKAKS 552



 Score = 40.4 bits (93), Expect = 3e-04
 Identities = 30/95 (31%), Positives = 46/95 (48%), Gaps = 8/95 (8%)

Query: 11  ELSAKDLKEKKEKVEEKASRKERKKEVVEEEENGAEEEEEETAEDGEEE-----DEGEEE 65
           E +   LKE  +  E++  +KE  K  V+EEE   E + +E  +  EEE      + EE+
Sbjct: 797 EKAKSPLKEDAKAPEKEIPKKEEVKSPVKEEEKPQEVKVKEPPKKAEEEKAPATPKTEEK 856

Query: 66  DEEEEEEDDEGPALKRAAEEEDE---ADPKRQKTE 97
            + ++EE  +  A K   EE+ E     PK  K E
Sbjct: 857 KDSKKEEAPKKEAPKPKVEEKKEPAVEKPKESKVE 891



 Score = 38.9 bits (89), Expect = 9e-04
 Identities = 27/99 (27%), Positives = 51/99 (51%), Gaps = 8/99 (8%)

Query: 1   MSEKSVEAAAELSAKDLKEKKEKVEEKASRKERKKEVVEEEENGAEEEEEETAEDGEEED 60
           + EK   A  +     ++ KKE+ E+K      KK    E+E  A+ E +E A+  E+ +
Sbjct: 874 VEEKKEPAVEKPKESKVEAKKEEAEDK------KKVPTPEKEAPAKVEVKEDAKPKEKTE 927

Query: 61  EGEEEDEEEEEEDDEGPALKR--AAEEEDEADPKRQKTE 97
             ++E ++ + ++   PA K+  A E++D  + K +K E
Sbjct: 928 VAKKEPDDAKAKEPSKPAEKKEAAPEKKDTKEEKAKKPE 966



 Score = 38.5 bits (88), Expect = 0.001
 Identities = 25/70 (35%), Positives = 39/70 (55%), Gaps = 5/70 (7%)

Query: 30  RKERKKEVVEEEENGA---EEEEEETAEDGEEEDEGEEEDEEEEEEDDEGPALKRA--AE 84
           + E K +VVE+ E      EE+ EET    E  +E E+E +EEE +++EG   + A   E
Sbjct: 439 KSEEKIKVVEKSEKETVIVEEQTEETQVTEEVTEEEEKEAKEEEGKEEEGGEEEEAEGGE 498

Query: 85  EEDEADPKRQ 94
           EE ++ P  +
Sbjct: 499 EETKSPPAEE 508



 Score = 38.5 bits (88), Expect = 0.001
 Identities = 28/98 (28%), Positives = 51/98 (52%), Gaps = 2/98 (2%)

Query: 7   EAAAELSAKDLKEKKEKVEEKA-SRKERKKEVVEEEENGAEEEEEETAEDG-EEEDEGEE 64
           EA +   AK  ++ K  V+E+A S  E K  V EE ++ AE +  E A+   +EE +  E
Sbjct: 591 EAKSPAEAKSPEKAKSPVKEEAKSPAEAKSPVKEEAKSPAEVKSPEKAKSPTKEEAKSPE 650

Query: 65  EDEEEEEEDDEGPALKRAAEEEDEADPKRQKTENGASA 102
           + +  E+E+ + P   ++  + +   P++ K+   A A
Sbjct: 651 KAKSPEKEEAKSPEKAKSPVKAEAKSPEKAKSPVKAEA 688



 Score = 38.5 bits (88), Expect = 0.001
 Identities = 33/96 (34%), Positives = 53/96 (55%), Gaps = 9/96 (9%)

Query: 3   EKSVEAAAELSAKDLKEKKEKVEEKASRKERKKEVVEEE-ENGAEEEEEETAEDGEEEDE 61
           +K+ E  A  + K  +EKK+  +E+A +KE  K  VEE+ E   E+ +E   E  +EE E
Sbjct: 840 KKAEEEKAPATPKT-EEKKDSKKEEAPKKEAPKPKVEEKKEPAVEKPKESKVEAKKEEAE 898

Query: 62  GEEEDEEEEEEDDEGPALKRAAEEEDEADPKRQKTE 97
            +++    E+   E PA     E +++A PK +KTE
Sbjct: 899 DKKKVPTPEK---EAPA---KVEVKEDAKPK-EKTE 927



 Score = 38.1 bits (87), Expect = 0.002
 Identities = 31/104 (29%), Positives = 53/104 (50%), Gaps = 5/104 (4%)

Query: 2   SEKSVEAAAELSAKDLKEKKEKVEEKA--SRKERKKEVVEEEENGAEEEEEETAEDGEEE 59
           S+K      E     ++EKKE   EK   S+ E KKE  E+++     E+E  A+   +E
Sbjct: 859 SKKEEAPKKEAPKPKVEEKKEPAVEKPKESKVEAKKEEAEDKKKVPTPEKEAPAKVEVKE 918

Query: 60  D-EGEEEDEEEEEEDDEGPALK--RAAEEEDEADPKRQKTENGA 100
           D + +E+ E  ++E D+  A +  + AE+++ A  K+   E  A
Sbjct: 919 DAKPKEKTEVAKKEPDDAKAKEPSKPAEKKEAAPEKKDTKEEKA 962



 Score = 37.7 bits (86), Expect = 0.002
 Identities = 22/97 (22%), Positives = 45/97 (46%), Gaps = 2/97 (2%)

Query: 2   SEKSVEAAAELSAKDLKEKKEKVEEKASRKERKKEVVEEEENGAEEEEEETAEDGEEEDE 61
           S +  ++  +  AK  ++ K  V+ +A   E+ K  V+EE    E+ +    E+ +  ++
Sbjct: 662 SPEKAKSPVKAEAKSPEKAKSPVKAEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKSPEK 721

Query: 62  GEEEDEEEEE--EDDEGPALKRAAEEEDEADPKRQKT 96
            +   +EE +  E  + P  + A   E    P++ KT
Sbjct: 722 AKSPVKEEAKTPEKAKSPVKEEAKSPEKAKSPEKAKT 758



 Score = 37.7 bits (86), Expect = 0.002
 Identities = 31/108 (28%), Positives = 57/108 (52%), Gaps = 15/108 (13%)

Query: 4   KSVEAAAELSAKDLKE------KKEKVEEKASRKERKKEV-VEEEENGAEEEEE------ 50
           KS E A     +D K       KKE+V+     +E+ +EV V+E    AEEE+       
Sbjct: 794 KSPEKAKSPLKEDAKAPEKEIPKKEEVKSPVKEEEKPQEVKVKEPPKKAEEEKAPATPKT 853

Query: 51  ETAEDGEEEDEGEEEDEEEEEEDDEGPALKRAAEEEDEADPKRQKTEN 98
           E  +D ++E+  ++E  + + E+ + PA+++  E + EA  K+++ E+
Sbjct: 854 EEKKDSKKEEAPKKEAPKPKVEEKKEPAVEKPKESKVEA--KKEEAED 899



 Score = 37.4 bits (85), Expect = 0.003
 Identities = 30/102 (29%), Positives = 53/102 (51%), Gaps = 4/102 (3%)

Query: 3   EKSVEAAAELSAKDLKEKKEKVEEKA-SRKERKKEVVEEEENGAEEEEEETAED-GEEED 60
           E++    AE +A   KE K  V+E+A S  E K    EE ++ AE +  E A+   +EE 
Sbjct: 499 EETKSPPAEEAASPEKEAKSPVKEEAKSPAEAKSPEKEEAKSPAEVKSPEKAKSPAKEEA 558

Query: 61  EGEEEDEEEEEEDDEGPALKRAAEEEDEADPKRQKTENGASA 102
           +   E +  E+E+ + PA  ++ E+     P +++ ++ A A
Sbjct: 559 KSPPEAKSPEKEEAKSPAEVKSPEK--AKSPAKEEAKSPAEA 598



 Score = 35.4 bits (80), Expect = 0.010
 Identities = 23/97 (23%), Positives = 49/97 (50%), Gaps = 6/97 (6%)

Query: 7   EAAAELSAKDLKEKKEKVEEKASRKERKKEVVEEEENGAEEE---EEETAEDGEEEDEGE 63
           E A   + K  ++ K  V+E+    E+ K  ++E+    E+E   +EE     +EE++ +
Sbjct: 772 EEARSPADKFPEKAKSPVKEEVKSPEKAKSPLKEDAKAPEKEIPKKEEVKSPVKEEEKPQ 831

Query: 64  E---EDEEEEEEDDEGPALKRAAEEEDEADPKRQKTE 97
           E   ++  ++ E+++ PA  +  E++D    +  K E
Sbjct: 832 EVKVKEPPKKAEEEKAPATPKTEEKKDSKKEEAPKKE 868



 Score = 33.1 bits (74), Expect = 0.048
 Identities = 29/103 (28%), Positives = 46/103 (44%), Gaps = 14/103 (13%)

Query: 7   EAAAELSAKDLKEKKEKVEEKASRKERKKEVVEEEENG-----AEEEEEETAEDGEEEDE 61
           E   E   K+ KE++ K EE    +E + E  EEE        A   E+E     +EE +
Sbjct: 468 EEVTEEEEKEAKEEEGKEEEGG--EEEEAEGGEEETKSPPAEEAASPEKEAKSPVKEEAK 525

Query: 62  GEEEDEEEEEEDDEGPA-------LKRAAEEEDEADPKRQKTE 97
              E +  E+E+ + PA        K  A+EE ++ P+ +  E
Sbjct: 526 SPAEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPPEAKSPE 568



 Score = 33.1 bits (74), Expect = 0.048
 Identities = 19/66 (28%), Positives = 34/66 (51%), Gaps = 4/66 (6%)

Query: 19   EKKEKVEEKASRKERK----KEVVEEEENGAEEEEEETAEDGEEEDEGEEEDEEEEEEDD 74
            EKK+  EEKA + E K     +  E+++  ++E  +  AE  E+    +++D +  E+  
Sbjct: 953  EKKDTKEEKAKKPEEKPKTEAKAKEDDKTLSKEPSKPKAEKAEKSSSTDQKDSKPPEKAT 1012

Query: 75   EGPALK 80
            E  A K
Sbjct: 1013 EDKAAK 1018



 Score = 32.3 bits (72), Expect = 0.082
 Identities = 22/98 (22%), Positives = 44/98 (44%), Gaps = 3/98 (3%)

Query: 2   SEKSVEAAAELSAKDLKEKKEKVEEKASRKERKKEVVEEEENG---AEEEEEETAEDGEE 58
           S +  ++  +  AK  ++ K  V+E+A   E+ K  V+EE      A+  E+    D + 
Sbjct: 704 SPEKAKSPVKEEAKSPEKAKSPVKEEAKTPEKAKSPVKEEAKSPEKAKSPEKAKTLDVKS 763

Query: 59  EDEGEEEDEEEEEEDDEGPALKRAAEEEDEADPKRQKT 96
            +      EE     D+ P   ++  +E+   P++ K+
Sbjct: 764 PEAKTPAKEEARSPADKFPEKAKSPVKEEVKSPEKAKS 801



 Score = 31.6 bits (70), Expect = 0.14
 Identities = 24/110 (21%), Positives = 52/110 (47%), Gaps = 16/110 (14%)

Query: 7    EAAAELSAKDLKEKKEKVE---------------EKASRKERKKEVVEEEENGAEEEEEE 51
            EA A++  K+  + KEK E               + A +KE   E  + +E  A++ EE+
Sbjct: 909  EAPAKVEVKEDAKPKEKTEVAKKEPDDAKAKEPSKPAEKKEAAPEKKDTKEEKAKKPEEK 968

Query: 52   TAEDGEEEDEGEEEDEEEEEEDDEGPALKRAAEEEDEADPKRQKTENGAS 101
               + + +++ +   +E  +   E  A K ++ ++ ++ P  + TE+ A+
Sbjct: 969  PKTEAKAKEDDKTLSKEPSKPKAE-KAEKSSSTDQKDSKPPEKATEDKAA 1017



 Score = 29.3 bits (64), Expect = 0.70
 Identities = 23/121 (19%), Positives = 50/121 (41%), Gaps = 20/121 (16%)

Query: 2   SEKSVEAAAELSAKDLKEKKEKVEEKASRK------------------ERKKEVVEEEEN 43
           +++  ++  E  + + +E K   E K+  K                  E+ K  V+EE  
Sbjct: 554 AKEEAKSPPEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPAEAKSPEKAKSPVKEEAK 613

Query: 44  GAEEEEEETAEDGEE--EDEGEEEDEEEEEEDDEGPALKRAAEEEDEADPKRQKTENGAS 101
              E +    E+ +   E +  E+ +   +E+ + P   ++ E+E+   P++ K+   A 
Sbjct: 614 SPAEAKSPVKEEAKSPAEVKSPEKAKSPTKEEAKSPEKAKSPEKEEAKSPEKAKSPVKAE 673

Query: 102 A 102
           A
Sbjct: 674 A 674



 Score = 28.1 bits (61), Expect = 1.6
 Identities = 22/90 (24%), Positives = 44/90 (48%), Gaps = 6/90 (6%)

Query: 3   EKSVEAAAELSAKDLKEKKE---KVEEKASRKERKKEVVE---EEENGAEEEEEETAEDG 56
           EK +    E+ +   +E+K    KV+E   + E +K       EE+  +++EE    E  
Sbjct: 811 EKEIPKKEEVKSPVKEEEKPQEVKVKEPPKKAEEEKAPATPKTEEKKDSKKEEAPKKEAP 870

Query: 57  EEEDEGEEEDEEEEEEDDEGPALKRAAEEE 86
           + + E ++E   E+ ++ +  A K  AE++
Sbjct: 871 KPKVEEKKEPAVEKPKESKVEAKKEEAEDK 900



 Score = 26.9 bits (58), Expect = 3.5
 Identities = 23/100 (23%), Positives = 44/100 (44%), Gaps = 11/100 (11%)

Query: 7   EAAAELSAKDLKEKKEKVEEKASRKERKKEV-----------VEEEENGAEEEEEETAED 55
           EA     AK   +++ K  EKA   E+ K +            EE  + A++  E+    
Sbjct: 729 EAKTPEKAKSPVKEEAKSPEKAKSPEKAKTLDVKSPEAKTPAKEEARSPADKFPEKAKSP 788

Query: 56  GEEEDEGEEEDEEEEEEDDEGPALKRAAEEEDEADPKRQK 95
            +EE +  E+ +   +ED + P  +   +EE ++  K ++
Sbjct: 789 VKEEVKSPEKAKSPLKEDAKAPEKEIPKKEEVKSPVKEEE 828



 Score = 26.6 bits (57), Expect = 4.5
 Identities = 20/99 (20%), Positives = 43/99 (43%), Gaps = 6/99 (6%)

Query: 2   SEKSVEAAAELSAKDLKEKKEKVEEKASRKERKKEVVEEEENGAEEEEEETAEDGEEEDE 61
           S    ++  +  AK   E K   + K+  KE  K    E+    E+EE ++ E  +   +
Sbjct: 614 SPAEAKSPVKEEAKSPAEVKSPEKAKSPTKEEAKS--PEKAKSPEKEEAKSPEKAKSPVK 671

Query: 62  GEEEDEEEEEE----DDEGPALKRAAEEEDEADPKRQKT 96
            E +  E+ +     + + P   ++  +E+   P++ K+
Sbjct: 672 AEAKSPEKAKSPVKAEAKSPEKAKSPVKEEAKSPEKAKS 710


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.281    0.110    0.256 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 5,033,305
Number of Sequences: 37866
Number of extensions: 370758
Number of successful extensions: 45560
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 2205
Number of HSP's successfully gapped in prelim test: 542
Number of HSP's that attempted gapping in prelim test: 2557
Number of HSP's gapped (non-prelim): 17900
length of query: 102
length of database: 18,247,518
effective HSP length: 73
effective length of query: 29
effective length of database: 15,483,300
effective search space: 449015700
effective search space used: 449015700
T: 11
A: 40
X1: 18 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 46 (21.8 bits)
S2: 55 (25.8 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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