Guide to the Human Genome
Home | Table of Contents | Search text | Search genes | Search sequences | Purchase | FAQ | Blog | Help

Search of human proteins with 4559408

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|4559408 colony stimulating factor 2 receptor, beta precursor
[Homo sapiens]
         (897 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|4559408 colony stimulating factor 2 receptor, beta precursor ...  1868   0.0  
gi|18105032 type X collagen alpha 1 precursor [Homo sapiens]           70   7e-12
gi|163965366 nascent polypeptide-associated complex alpha subuni...    70   7e-12
gi|4557669 interleukin 4 receptor alpha chain isoform a precurso...    70   9e-12
gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo ...    70   9e-12
gi|19924097 synapsin I isoform Ib [Homo sapiens]                       69   2e-11
gi|4502951 collagen type III alpha 1 preproprotein [Homo sapiens]      68   4e-11
gi|110832843 TBP-associated factor 4 [Homo sapiens]                    66   1e-10
gi|19924099 synapsin I isoform Ia [Homo sapiens]                       66   1e-10
gi|89276751 alpha 1 type V collagen preproprotein [Homo sapiens]       65   3e-10
gi|116284398 WAS/WASL interacting protein family, member 1 [Homo...    65   3e-10
gi|38373695 WAS/WASL interacting protein family, member 1 [Homo ...    65   3e-10
gi|209571537 proline-rich protein BstNI subfamily 2 [Homo sapiens]     64   5e-10
gi|98985810 alpha 1 type XI collagen isoform B preproprotein [Ho...    63   1e-09
gi|98985808 alpha 1 type XI collagen isoform C preproprotein [Ho...    63   1e-09
gi|98985806 alpha 1 type XI collagen isoform A preproprotein [Ho...    63   1e-09
gi|15890086 type IV collagen alpha 5 isoform 2 precursor [Homo s...    63   1e-09
gi|4502955 type IV collagen alpha 5 isoform 1 precursor [Homo sa...    63   1e-09
gi|15890088 type IV collagen alpha 5 isoform 3 precursor [Homo s...    63   1e-09
gi|146219843 Snf2-related CBP activator protein [Homo sapiens]         63   1e-09
gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi...    62   2e-09
gi|41349482 proline-rich protein BstNI subfamily 1 isoform 1 pre...    62   2e-09
gi|89363017 alpha 2 type V collagen preproprotein [Homo sapiens]       62   2e-09
gi|239754955 PREDICTED: similar to COL22A1 protein [Homo sapiens]      62   3e-09
gi|111118972 collagen, type XI, alpha 2 isoform 2 preproprotein ...    61   4e-09
gi|111118968 collagen, type XI, alpha 2 isoform 3 preproprotein ...    61   4e-09
gi|111118970 collagen, type XI, alpha 2 isoform 1 preproprotein ...    61   4e-09
gi|32964830 collagen, type VIII, alpha 2 [Homo sapiens]                60   9e-09
gi|46852161 methyl-CpG binding domain protein 6 [Homo sapiens]         60   9e-09
gi|38373671 SEC24-related protein C [Homo sapiens]                     60   1e-08

>gi|4559408 colony stimulating factor 2 receptor, beta precursor
           [Homo sapiens]
          Length = 897

 Score = 1868 bits (4840), Expect = 0.0
 Identities = 897/897 (100%), Positives = 897/897 (100%)

Query: 1   MVLAQGLLSMALLALCWERSLAGAEETIPLQTLRCYNDYTSHITCRWADTQDAQRLVNVT 60
           MVLAQGLLSMALLALCWERSLAGAEETIPLQTLRCYNDYTSHITCRWADTQDAQRLVNVT
Sbjct: 1   MVLAQGLLSMALLALCWERSLAGAEETIPLQTLRCYNDYTSHITCRWADTQDAQRLVNVT 60

Query: 61  LIRRVNEDLLEPVSCDLSDDMPWSACPHPRCVPRRCVIPCQSFVVTDVDYFSFQPDRPLG 120
           LIRRVNEDLLEPVSCDLSDDMPWSACPHPRCVPRRCVIPCQSFVVTDVDYFSFQPDRPLG
Sbjct: 61  LIRRVNEDLLEPVSCDLSDDMPWSACPHPRCVPRRCVIPCQSFVVTDVDYFSFQPDRPLG 120

Query: 121 TRLTVTLTQHVQPPEPRDLQISTDQDHFLLTWSVALGSPQSHWLSPGDLEFEVVYKRLQD 180
           TRLTVTLTQHVQPPEPRDLQISTDQDHFLLTWSVALGSPQSHWLSPGDLEFEVVYKRLQD
Sbjct: 121 TRLTVTLTQHVQPPEPRDLQISTDQDHFLLTWSVALGSPQSHWLSPGDLEFEVVYKRLQD 180

Query: 181 SWEDAAILLSNTSQATLGPEHLMPSSTYVARVRTRLAPGSRLSGRPSKWSPEVCWDSQPG 240
           SWEDAAILLSNTSQATLGPEHLMPSSTYVARVRTRLAPGSRLSGRPSKWSPEVCWDSQPG
Sbjct: 181 SWEDAAILLSNTSQATLGPEHLMPSSTYVARVRTRLAPGSRLSGRPSKWSPEVCWDSQPG 240

Query: 241 DEAQPQNLECFFDGAAVLSCSWEVRKEVASSVSFGLFYKPSPDAGEEECSPVLREGLGSL 300
           DEAQPQNLECFFDGAAVLSCSWEVRKEVASSVSFGLFYKPSPDAGEEECSPVLREGLGSL
Sbjct: 241 DEAQPQNLECFFDGAAVLSCSWEVRKEVASSVSFGLFYKPSPDAGEEECSPVLREGLGSL 300

Query: 301 HTRHHCQIPVPDPATHGQYIVSVQPRRAEKHIKSSVNIQMAPPSLNVTKDGDSYSLRWET 360
           HTRHHCQIPVPDPATHGQYIVSVQPRRAEKHIKSSVNIQMAPPSLNVTKDGDSYSLRWET
Sbjct: 301 HTRHHCQIPVPDPATHGQYIVSVQPRRAEKHIKSSVNIQMAPPSLNVTKDGDSYSLRWET 360

Query: 361 MKMRYEHIDHTFEIQYRKDTATWKDSKTETLQNAHSMALPALEPSTRYWARVRVRTSRTG 420
           MKMRYEHIDHTFEIQYRKDTATWKDSKTETLQNAHSMALPALEPSTRYWARVRVRTSRTG
Sbjct: 361 MKMRYEHIDHTFEIQYRKDTATWKDSKTETLQNAHSMALPALEPSTRYWARVRVRTSRTG 420

Query: 421 YNGIWSEWSEARSWDTESVLPMWVLALIVIFLTIAVLLALRFCGIYGYRLRRKWEEKIPN 480
           YNGIWSEWSEARSWDTESVLPMWVLALIVIFLTIAVLLALRFCGIYGYRLRRKWEEKIPN
Sbjct: 421 YNGIWSEWSEARSWDTESVLPMWVLALIVIFLTIAVLLALRFCGIYGYRLRRKWEEKIPN 480

Query: 481 PSKSHLFQNGSAELWPPGSMSAFTSGSPPHQGPWGSRFPELEGVFPVGFGDSEVSPLTIE 540
           PSKSHLFQNGSAELWPPGSMSAFTSGSPPHQGPWGSRFPELEGVFPVGFGDSEVSPLTIE
Sbjct: 481 PSKSHLFQNGSAELWPPGSMSAFTSGSPPHQGPWGSRFPELEGVFPVGFGDSEVSPLTIE 540

Query: 541 DPKHVCDPPSGPDTTPAASDLPTEQPPSPQPGPPAASHTPEKQASSFDFNGPYLGPPHSR 600
           DPKHVCDPPSGPDTTPAASDLPTEQPPSPQPGPPAASHTPEKQASSFDFNGPYLGPPHSR
Sbjct: 541 DPKHVCDPPSGPDTTPAASDLPTEQPPSPQPGPPAASHTPEKQASSFDFNGPYLGPPHSR 600

Query: 601 SLPDILGQPEPPQEGGSQKSPPPGSLEYLCLPAGGQVQLVPLAQAMGPGQAVEVERRPSQ 660
           SLPDILGQPEPPQEGGSQKSPPPGSLEYLCLPAGGQVQLVPLAQAMGPGQAVEVERRPSQ
Sbjct: 601 SLPDILGQPEPPQEGGSQKSPPPGSLEYLCLPAGGQVQLVPLAQAMGPGQAVEVERRPSQ 660

Query: 661 GAAGSPSLESGGGPAPPALGPRVGGQDQKDSPVAIPMSSGDTEDPGVASGYVSSADLVFT 720
           GAAGSPSLESGGGPAPPALGPRVGGQDQKDSPVAIPMSSGDTEDPGVASGYVSSADLVFT
Sbjct: 661 GAAGSPSLESGGGPAPPALGPRVGGQDQKDSPVAIPMSSGDTEDPGVASGYVSSADLVFT 720

Query: 721 PNSGASSVSLVPSLGLPSDQTPSLCPGLASGPPGAPGPVKSGFEGYVELPPIEGRSPRSP 780
           PNSGASSVSLVPSLGLPSDQTPSLCPGLASGPPGAPGPVKSGFEGYVELPPIEGRSPRSP
Sbjct: 721 PNSGASSVSLVPSLGLPSDQTPSLCPGLASGPPGAPGPVKSGFEGYVELPPIEGRSPRSP 780

Query: 781 RNNPVPPEAKSPVLNPGERPADVSPTSPQPEGLLVLQQVGDYCFLPGLGPGPLSLRSKPS 840
           RNNPVPPEAKSPVLNPGERPADVSPTSPQPEGLLVLQQVGDYCFLPGLGPGPLSLRSKPS
Sbjct: 781 RNNPVPPEAKSPVLNPGERPADVSPTSPQPEGLLVLQQVGDYCFLPGLGPGPLSLRSKPS 840

Query: 841 SPGPGPEIKNLDQAFQVKKPPGQAVPQVPVIQLFKALKQQDYLSLPPWEVNKPGEVC 897
           SPGPGPEIKNLDQAFQVKKPPGQAVPQVPVIQLFKALKQQDYLSLPPWEVNKPGEVC
Sbjct: 841 SPGPGPEIKNLDQAFQVKKPPGQAVPQVPVIQLFKALKQQDYLSLPPWEVNKPGEVC 897


>gi|18105032 type X collagen alpha 1 precursor [Homo sapiens]
          Length = 680

 Score = 70.5 bits (171), Expect = 7e-12
 Identities = 112/401 (27%), Positives = 140/401 (34%), Gaps = 59/401 (14%)

Query: 497 PGSMSAFTSGSPPHQGPWGSRFPELEGVFPVGFGDSEVSPLTIEDPKHVCDPPSGPDTTP 556
           PG       G P  QGP G+  P        GF   + +P          +   G    P
Sbjct: 147 PGPAGISVPGKPGQQGPTGAPGPR-------GFPGEKGAPGVPGMNGQKGEMGYGAPGRP 199

Query: 557 AASDLPTEQPPSPQPGPPAASHTPE---------KQASSFDFNGPYLGPPHSRSLPDILG 607
               LP  Q P+   GPP      E         K    F      +GPP  +  P   G
Sbjct: 200 GERGLPGPQGPTGPSGPPGVGKRGENGVPGQPGIKGDRGFPGEMGPIGPPGPQGPPGERG 259

Query: 608 QPEPPQEGGSQKSPPPGSLEYLCLPAGGQVQLVPLAQAMG-PG-QAVEVERRPSQGAAGS 665
                + G +     PG      LP    +   P     G PG   ++ ER P+ G  G 
Sbjct: 260 PEGIGKPGAAGAPGQPGIPGTKGLPGAPGIAGPPGPPGFGKPGLPGLKGERGPA-GLPGG 318

Query: 666 PSLESGGGPA-----PPALGP--RVGGQDQKDSPVA--IPMSSGDTEDPGVASGYVSSAD 716
           P  +   GPA     P   GP   +G Q  K  P +  +P   G+T   G A GY  +  
Sbjct: 319 PGAKGEQGPAGLPGKPGLTGPPGNMGPQGPKGIPGSHGLPGPKGETGPAGPA-GYPGAKG 377

Query: 717 LVFTPNS-GASSVSLVPSL----GLPSDQTPSLCPGLASGPPGAPGPVKSGFEGYVELPP 771
              +P S G       P L    G P    P   PG+  GPPG PGPV  G  G   +P 
Sbjct: 378 ERGSPGSDGKPGYPGKPGLDGPKGNPGLPGPKGDPGVG-GPPGLPGPV--GPAGAKGMPG 434

Query: 772 IEGRSPRSPRNNPVPPEAKSPVLN------PGERPADVSPTSPQPEGLLVLQQVGDYCFL 825
             G +   PR  P  P  + P+        PG +    SP  P P G+      G     
Sbjct: 435 HNGEA--GPRGAPGIPGTRGPIGPPGIPGFPGSKGDPGSPGPPGPAGIATKGLNGPTG-- 490

Query: 826 PGLGPGPLSLRSKPSSPG-PGPEIKNLDQAFQVKKPPGQAV 865
           P   PGP     +P  PG PGP             PPGQAV
Sbjct: 491 PPGPPGPRGHSGEPGLPGPPGP-----------PGPPGQAV 520



 Score = 47.8 bits (112), Expect = 5e-05
 Identities = 81/325 (24%), Positives = 100/325 (30%), Gaps = 64/325 (19%)

Query: 571 PGPPAASHTPEKQASSFDFNGPYLGPPHSRSLPDILGQPEPPQEGGSQKSPPPGSLEYLC 630
           PGPP  +        S     P  G P  +  P + G P P   G       PG      
Sbjct: 62  PGPPGPAGPRGHPGPSGPPGKPGYGSPGLQGEPGLPGPPGPSAVGKPGVPGLPGK----- 116

Query: 631 LPAGGQVQLVPLAQAMGPGQAVEVERRPSQGAAGSPSLESGGGPAPPAL----GPRVGGQ 686
                            PG+      +   G AG P     G P PP +    G  V G+
Sbjct: 117 -----------------PGERGPYGPKGDVGPAGLPGPR--GPPGPPGIPGPAGISVPGK 157

Query: 687 DQKDSPVAIPMSSG---DTEDPGVASGYVSSADLVFTPNSGASSVSLVPSLGLPSDQTPS 743
             +  P   P   G   +   PGV        ++      G  +       GLP  Q P+
Sbjct: 158 PGQQGPTGAPGPRGFPGEKGAPGVPGMNGQKGEM------GYGAPGRPGERGLPGPQGPT 211

Query: 744 LCPGLASGPPGAPGPVKSGFEGYVELPPIEG-------RSPRSPRNNPVPPEAKSP--VL 794
                  GP G PG  K G  G    P I+G         P  P     PP  + P  + 
Sbjct: 212 -------GPSGPPGVGKRGENGVPGQPGIKGDRGFPGEMGPIGPPGPQGPPGERGPEGIG 264

Query: 795 NPGERPADVSPTSPQPEGLLVLQQVGDYCFLPGLG----PGPLSLRSKPSSPGPGPEIK- 849
            PG   A   P  P  +GL     +      PG G    PG    R     PG GP  K 
Sbjct: 265 KPGAAGAPGQPGIPGTKGLPGAPGIAGPPGPPGFGKPGLPGLKGERGPAGLPG-GPGAKG 323

Query: 850 -----NLDQAFQVKKPPGQAVPQVP 869
                 L     +  PPG   PQ P
Sbjct: 324 EQGPAGLPGKPGLTGPPGNMGPQGP 348



 Score = 47.4 bits (111), Expect = 6e-05
 Identities = 83/330 (25%), Positives = 107/330 (32%), Gaps = 61/330 (18%)

Query: 497 PGSMSAFTSGSPPHQGPWGSRFPELEGVFPVGFGDSEVSP-----LTIEDPKHVCDPPSG 551
           PG M     G P  QGP G R PE  G+   G   +   P       +     +  PP  
Sbjct: 240 PGEMGPI--GPPGPQGPPGERGPE--GIGKPGAAGAPGQPGIPGTKGLPGAPGIAGPPGP 295

Query: 552 PDT-TPAASDLPTEQPPSPQPGPPAAS--HTPEKQASSFDFNGP--YLGPPHSRSLPDIL 606
           P    P    L  E+ P+  PG P A     P          GP   +GP   + +P   
Sbjct: 296 PGFGKPGLPGLKGERGPAGLPGGPGAKGEQGPAGLPGKPGLTGPPGNMGPQGPKGIPGSH 355

Query: 607 GQPEPPQEGG-SQKSPPPGSLEYLCLPAGGQVQLVPLAQAM----------GPGQAVEVE 655
           G P P  E G +  +  PG+      P        P    +          GP     V 
Sbjct: 356 GLPGPKGETGPAGPAGYPGAKGERGSPGSDGKPGYPGKPGLDGPKGNPGLPGPKGDPGVG 415

Query: 656 RRPSQ----GAAGSPSLESGGGPAPPALGPRVGGQDQKDSPVAIPMSSGDTEDPGVASGY 711
             P      G AG+  +    G A P   P + G      P  IP   G   DPG     
Sbjct: 416 GPPGLPGPVGPAGAKGMPGHNGEAGPRGAPGIPGTRGPIGPPGIPGFPGSKGDPG----- 470

Query: 712 VSSADLVFTPNSGASSVSLVPSLGLPSDQTPSLCPGLASGPPGAPGPVKSGFEGYVELPP 771
                     + G    + + + GL             +GPPG PGP   G  G   LP 
Sbjct: 471 ----------SPGPPGPAGIATKGLNG----------PTGPPGPPGP--RGHSGEPGLPG 508

Query: 772 IEGRSPRSPRNNPVPPEAKSPVLNPGERPA 801
             G  P  P    V PE     +  G+RP+
Sbjct: 509 PPG--PPGPPGQAVMPEG---FIKAGQRPS 533


>gi|163965366 nascent polypeptide-associated complex alpha subunit
            isoform a [Homo sapiens]
          Length = 2078

 Score = 70.5 bits (171), Expect = 7e-12
 Identities = 112/426 (26%), Positives = 143/426 (33%), Gaps = 72/426 (16%)

Query: 496  PPGSMSAFTSGSPPHQGPWGSRFPELEGVFPVGFGDSEVSPLTIEDPKHVCDPPSG---- 551
            PP +      G P    P G+  P    V P      + SP     PK    PP+     
Sbjct: 988  PPAATPPSPKGGPATPSPKGAPTPP--AVTPPS---PKGSPAATPFPKGASTPPAATPPS 1042

Query: 552  PDTTPAASDLPTEQP-------PSPQPGPPAAS----HTPEKQASSFDFNGPYLGPPHSR 600
            P  +PAA+ LP   P       PSP+ GP   S     TP          GP    P   
Sbjct: 1043 PKGSPAATPLPKGAPTTPAATLPSPKGGPATPSLKGAPTPPAATPPSPKGGPATPSPKGA 1102

Query: 601  SLPDILGQPEP------PQEGGSQKSP---PPGSLEYLCLPAGGQVQLVPLAQAMGPGQA 651
             +P     P P      P   G+  +P   PP     L  P        P A    P   
Sbjct: 1103 PMPPAATPPSPKGGLATPPHKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGG 1162

Query: 652  VEV---ERRPSQGAAGSPSLESG-------GGPAPPALGP--RVGG------QDQKDSPV 693
            +     +  P+  AA  PS + G       G P  PA  P    GG      +    +P 
Sbjct: 1163 LATPPPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPA 1222

Query: 694  AIPMS-SGDTEDPGVASGYVSSADLVFTPNSGASSVSLVPSLGLPSDQTPSLCPGLASGP 752
            A P S  G    P       + A    +P  G ++     +   P+   PSL  GLA+ P
Sbjct: 1223 ATPPSPKGGLATPSPKGAPTTPAATPPSPKGGPATPPPKGAPTPPAATPPSLKGGLATPP 1282

Query: 753  -PGAPGPVKSGFEGYVELPPIEGRSPRS--PRNNPVPPEA--KSPVLNPGERPADVSP-- 805
              GAP P        V  PP     P +  P+  P PP A   SP  +PG  P   +P  
Sbjct: 1283 HKGAPNPA-------VVTPPSPKGGPATSPPKGAPTPPAATPPSPKGSPGTPPPKGAPTP 1335

Query: 806  ---TSPQPEGLLVLQQVGDYCFLPGLGPGPLSLRSK--PSSPGPGPEIKNLDQAFQVKKP 860
               T P P+G   L         P    GP +  SK  P+ P   P  K           
Sbjct: 1336 PAVTPPSPKGTPTLPAT-----TPSSKGGPTTPSSKEGPTPPAATPSHKGGPAMTPPSPK 1390

Query: 861  PGQAVP 866
             G A+P
Sbjct: 1391 RGPAIP 1396



 Score = 60.8 bits (146), Expect = 5e-09
 Identities = 96/396 (24%), Positives = 128/396 (32%), Gaps = 92/396 (23%)

Query: 526  PVGFGDSEVSPLTIEDPKHVCDPPSGPDTTPAASDLPTEQPPSPQPG------------- 572
            P+G   S VSP+             G   +PA +  PT  PPSP+               
Sbjct: 820  PIGNLSSPVSPVEASFLPENSLSFQGSKDSPATTHSPT--PPSPKGAPTPSAVTPLSPKG 877

Query: 573  ---PPAASHTPEKQASSFDFNGPYL--------------GPPHSRSLPDILGQPEPPQEG 615
               PP  + TP      F   GP                 P  +R+ P   G P  P   
Sbjct: 878  VTLPPKETPTPSVVNLPFPKEGPATPAPKQAPALSMTSSSPKKARATPAPKGIPASPSPK 937

Query: 616  GSQKSP---PPGSLEYLCLPAGGQVQLVPLAQAMGP--GQAVEVER-RPSQGAAGSPSLE 669
            G+   P   PP        P+       P A    P  G A    +  P+  AA  PS +
Sbjct: 938  GAPTPPAATPPSPKGGPATPSPKWAPTPPAATPPSPKGGPATPSPKGAPTPPAATPPSPK 997

Query: 670  SG-------GGPAPPALGPRVGGQDQKDSPVAIPMSSGDTEDPGVASGYVSSADLVFTPN 722
             G       G P PPA+ P       K SP A P   G +  P         +       
Sbjct: 998  GGPATPSPKGAPTPPAVTP----PSPKGSPAATPFPKGASTPPAATPPSPKGSPAATPLP 1053

Query: 723  SGASSVSLVPSLGLPSDQTPSLCPGL--ASGPPGAPGPVKSGFEGYVELPPIEGRSPRSP 780
             GA +    P+  LPS +     P L  A  PP A  P   G           G +  SP
Sbjct: 1054 KGAPT---TPAATLPSPKGGPATPSLKGAPTPPAATPPSPKG-----------GPATPSP 1099

Query: 781  RNNPVPPEAKSP-----VLNPGERPADVSP--TSPQPEGLLVLQQVGDYCFLPGLGPGPL 833
            +  P+PP A  P     +  P  + A  +P  T P P+G L               P P 
Sbjct: 1100 KGAPMPPAATPPSPKGGLATPPHKGAPTTPAATPPSPKGGLAT-------------PPPK 1146

Query: 834  SLRSKPSSPGPGPEIKNLDQAFQVKKPPGQAVPQVP 869
               + P++  P P+         +  PP +  P  P
Sbjct: 1147 GAPTTPAATPPSPK-------GGLATPPPKGAPTTP 1175



 Score = 60.8 bits (146), Expect = 5e-09
 Identities = 80/307 (26%), Positives = 105/307 (34%), Gaps = 49/307 (15%)

Query: 549  PSGPDTTPAASDLPTEQPPSPQPGPPAASHTPEKQASSFDFNGPYLGP-PHSRSLPDILG 607
            P     TPA   +P    P   P PPAA  TP           P   P P + + P   G
Sbjct: 918  PKKARATPAPKGIPASPSPKGAPTPPAA--TPPSPKGGPATPSPKWAPTPPAATPPSPKG 975

Query: 608  QPEPPQEGGSQKSP---PPGSLEYLCLPAGGQVQLVPLAQAMGPGQAVEVERRPSQGAAG 664
             P  P   G+   P   PP        P GG     P   A  P        + S  A  
Sbjct: 976  GPATPSPKGAPTPPAATPPS-------PKGGPATPSPKG-APTPPAVTPPSPKGSPAATP 1027

Query: 665  SPSLESGGGPAPPALGPRVGGQDQKDSPVAIPMSSGDTEDPGVASGYVSSADLVFTPNSG 724
             P     G   PPA  P       K SP A P+  G    P         A  + +P  G
Sbjct: 1028 FPK----GASTPPAATP----PSPKGSPAATPLPKGAPTTP---------AATLPSPKGG 1070

Query: 725  ASSVSLVPSLGLPSDQTPSLCPGLAS-GPPGAPGP---VKSGFEGYVELPPIEGRSPRSP 780
             ++ SL  +   P+   PS   G A+  P GAP P        +G +  PP +G +P +P
Sbjct: 1071 PATPSLKGAPTPPAATPPSPKGGPATPSPKGAPMPPAATPPSPKGGLATPPHKG-APTTP 1129

Query: 781  RNNPVPPEAKSPVLNPGERPADVSPTSPQPEGLLVLQQVGDYCFLPGLGPGPLSLRSKPS 840
               P  P+       P   P   + T P P+G L               P P    + P+
Sbjct: 1130 AATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLAT-------------PPPKGAPTTPA 1176

Query: 841  SPGPGPE 847
            +  P P+
Sbjct: 1177 ATPPSPK 1183



 Score = 52.4 bits (124), Expect = 2e-06
 Identities = 93/396 (23%), Positives = 131/396 (33%), Gaps = 59/396 (14%)

Query: 496  PPGSMSAFTSGSPPHQGPWGSRFPELEGVFPVGFGDSEVSPLTIEDPKHVCDPPSG---- 551
            PP +      GSP    P G+  P    V P     +   P T    K     PS     
Sbjct: 1312 PPAATPPSPKGSPGTPPPKGAPTPP--AVTPPSPKGTPTLPATTPSSKGGPTTPSSKEGP 1369

Query: 552  --PDTTPAASDLPTEQPPSPQPGP-----------PAASHTPEKQASSFDFNGPYLGPPH 598
              P  TP+    P   PPSP+ GP           PA      K+A +          P 
Sbjct: 1370 TPPAATPSHKGGPAMTPPSPKRGPAIPSPKGDPTSPAVIPLSPKKAPATPVTREGAATPS 1429

Query: 599  SRSLPDILGQPEPPQEGGSQKSPPPGSLEYLCLPAGGQVQLVPLAQAMGPGQAVEVERRP 658
               L      P   ++  +  +P  G       PA    +  P   A+ P    E    P
Sbjct: 1430 KGDLTPPAVTPVSLKKAPATSAPKGG-------PATPSSKGDPTLPAVTPPSPKE-PPAP 1481

Query: 659  SQGAAGSPSLESGGGPAP------PALGPRVGGQDQKDSPVAIPMSSGDTEDPGVASGYV 712
             Q A  S   ++   PAP      PA+ P         SP  +P +     DP   +  +
Sbjct: 1482 KQVATSSSPKKAPATPAPMGAPTLPAVIP--------SSPKEVPATPSSRRDPIAPTATL 1533

Query: 713  SSADLVFTPNSGASSVSLV-PSLGLPSDQTPSLCPGLASGPPGAPGPVKSGFEGYVELPP 771
             S     TP + A   +L+ P++ +PS   P   P + +       P          + P
Sbjct: 1534 LSKK---TPATLAPKEALIPPAMTVPS---PKKTPAIPTPKEAPATPSSKEASSPPAVTP 1587

Query: 772  IEGRSPRSPRNNPVPPEAKSPVLNPGERPADVSPTSPQPE-GLLVLQQVGDYCFLPGLGP 830
               +   SP+   +PP   SP  +P E P   + T P PE G       G     P    
Sbjct: 1588 STYKGAPSPKELLIPPAVTSP--SPKEAPTPPAVTPPSPEKGPATPAPKGTPTSPP---V 1642

Query: 831  GPLSLRSKPSSPGP-----GPEIKNLDQAFQVKKPP 861
             P SL+  P+SP       G  +    +    KK P
Sbjct: 1643 TPSSLKDSPTSPASVTCKMGATVPQASKGLPAKKGP 1678


>gi|4557669 interleukin 4 receptor alpha chain isoform a precursor
           [Homo sapiens]
          Length = 825

 Score = 70.1 bits (170), Expect = 9e-12
 Identities = 153/688 (22%), Positives = 238/688 (34%), Gaps = 143/688 (20%)

Query: 246 QNLECFFDGAAVLSCSWEVRKEVASSVSFGLFYKPSPDAGEEE-CSPVLREGLGSLHTRH 304
           Q   C  D  ++ +C W++      S    L Y+      E   C P    G G +    
Sbjct: 30  QEPTCVSDYMSISTCEWKMNGPTNCSTELRLLYQLVFLLSEAHTCIPENNGGAGCV---- 85

Query: 305 HCQIPVPDPATHGQYIVSV---QPRRAEKHIKSSVNIQ-MAPPSLNV-TKDGDSYSLRWE 359
            C + + D  +   Y + +   Q    +   K S +++  AP +L V T   D+  L W 
Sbjct: 86  -CHLLMDDVVSADNYTLDLWAGQQLLWKGSFKPSEHVKPRAPGNLTVHTNVSDTLLLTWS 144

Query: 360 TM----KMRYEHIDHTFEIQYRKDTATWKDSKTETLQNAHSMALPALEPSTRYWARVRVR 415
                    Y H+ +   I    D A ++      L+ +  +A   L+    Y  R RVR
Sbjct: 145 NPYPPDNYLYNHLTYAVNIWSENDPADFRIYNVTYLEPSLRIAASTLKSGISY--RARVR 202

Query: 416 TSRTGYNGIWSEWSEARSWDTESVLPMWVLALIVIFLTIAVLLAL-RFCGIYGYRLRRKW 474
                YN  WSEWS +  W      P     L+ + ++  V+LA+   C +   +++++W
Sbjct: 203 AWAQCYNTTWSEWSPSTKWHNSYREPFEQHLLLGVSVSCIVILAVCLLCYVSITKIKKEW 262

Query: 475 EEKIPNPSKSHL----FQNGSAELWPPGSMSAFTSGSPPHQGP-WGSRFPELEGVFP--- 526
            ++IPNP++S L     Q+     W   S      G  P + P W +   +L   F    
Sbjct: 263 WDQIPNPARSRLVAIIIQDAQGSQWEKRS-----RGQEPAKCPHWKNCLTKLLPCFLEHN 317

Query: 527 ----------------VGFGDSEVSPLTIEDPKHVCDPPS-----GPDTTPAASDLPTEQ 565
                            G G S   P  +E  K V  P S       +   A  +   E+
Sbjct: 318 MKRDEDPHKAAKEMPFQGSGKSAWCP--VEISKTVLWPESISVVRCVELFEAPVECEEEE 375

Query: 566 PPSPQPGPPAASHTPEKQASSFDFNGPYLGPPHSRSL-PDILGQPE----PPQEGGSQKS 620
               + G   AS  PE     F      +    + SL  D+LG+          G S   
Sbjct: 376 EVEEEKGSFCAS--PESSRDDFQEGREGIVARLTESLFLDLLGEENGGFCQQDMGESCLL 433

Query: 621 PPPGS----LEYLCLPAGGQVQLVPLAQAMGPGQAVEVERRPSQG--------------- 661
           PP GS    + +   P+ G  +  P     G  Q + +E  P                  
Sbjct: 434 PPSGSTSAHMPWDEFPSAGPKEAPP----WGKEQPLHLEPSPPASPTQSPDNLTCTETPL 489

Query: 662 -AAGSPSLES-----GGGPAPPALG-------------PRVGGQDQKDSPVAIPMSSGDT 702
             AG+P+  S        P P  LG             P +    Q   P  +P    +T
Sbjct: 490 VIAGNPAYRSFSNSLSQSPCPRELGPDPLLARHLEEVEPEMPCVPQLSEPTTVPQPEPET 549

Query: 703 EDP---------GVASGYVSS-----ADLVFTPNSGASSVSLVPSLGLPSD----QTPSL 744
            +          G A+  VS+      + V     G +  S V  LG P +       SL
Sbjct: 550 WEQILRRNVLQHGAAAAPVSAPTSGYQEFVHAVEQGGTQASAVVGLGPPGEAGYKAFSSL 609

Query: 745 CPGLASGPPGAPGPVKSGFEGY----------------VELP----PIEGRSPRSPRNNP 784
               A  P        SG EGY                V +P     ++   PRSP+++ 
Sbjct: 610 LASSAVSPEKCGFGASSGEEGYKPFQDLIPGCPGDPAPVPVPLFTFGLDREPPRSPQSSH 669

Query: 785 VPPEAKSPV-LNPGERPADVSPTSPQPE 811
           +P  +   + L PGE+  D+ P  P P+
Sbjct: 670 LPSSSPEHLGLEPGEKVEDM-PKPPLPQ 696



 Score = 31.2 bits (69), Expect = 4.5
 Identities = 30/125 (24%), Positives = 50/125 (40%), Gaps = 10/125 (8%)

Query: 30  LQTLRCYNDYTSHITCRWADTQDAQRLVNVTLIRRVNEDLLEPVSCDLSDDMPWSACPHP 89
           LQ   C +DY S  TC W           + L+ ++   L E  +C + ++   + C   
Sbjct: 29  LQEPTCVSDYMSISTCEWKMNGPTNCSTELRLLYQLVFLLSEAHTC-IPENNGGAGCV-- 85

Query: 90  RCVPRRCVIPCQSFVVTDVDYFSFQPDRPLGTRLTVTLTQHVQPPEPRDLQISTD-QDHF 148
                 C +     V  D         + L  + +   ++HV+P  P +L + T+  D  
Sbjct: 86  ------CHLLMDDVVSADNYTLDLWAGQQLLWKGSFKPSEHVKPRAPGNLTVHTNVSDTL 139

Query: 149 LLTWS 153
           LLTWS
Sbjct: 140 LLTWS 144


>gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo
           sapiens]
          Length = 5537

 Score = 70.1 bits (170), Expect = 9e-12
 Identities = 108/434 (24%), Positives = 152/434 (35%), Gaps = 80/434 (18%)

Query: 494 LWPPGSMSAFTSG-----SPPHQGPWGSRF-------PELEGVFPVGFGDSEVSPLTIED 541
           L PP   S F+       SPP + P            PE   + P  F +S +SP     
Sbjct: 503 LSPPPESSPFSPLEESPLSPPEESPPSPALETPLSPPPEASPLSPP-FEESPLSP----P 557

Query: 542 PKHVCDPPSGPDTTPAASDLPTEQPPSPQPGPPAASHTPEKQASSFDFNGPYLGPPHSR- 600
           P+ +  P S P      S  P E P SP P     S  PE       F    L PP    
Sbjct: 558 PEEL--PTSPPPEASRLSPPPEESPMSPPPEESPMSPPPEASRLFPPFEESPLSPPPEES 615

Query: 601 --SLPDILGQPEPPQEGGSQKSPPPGSLEYLCLPAGGQVQLVPLAQAMGPGQAVEVERRP 658
             S P    +  PP E  S  SPPP        P   ++  +P+   + P         P
Sbjct: 616 PLSPPPEASRLSPPPE-DSPMSPPPEESPMSPPPEVSRLSPLPVVSRLSP--------PP 666

Query: 659 SQGAAGSPSLESGGGPAPPA--LGPRVGGQDQKDSPVAIPMSSGDTEDPGVASGYVSSAD 716
            +     P  ES   P P A  L P       +DSP + P        P           
Sbjct: 667 EESPLSPPPEESPTSPPPEASRLSP-----PPEDSPTSPPPEDSPASPP----------- 710

Query: 717 LVFTPNSGASSVSLVPSLGLPSDQTPSLCPGLASGPPGAPGPVKSGFEGYVELPPIEGRS 776
               P     S+ L  S  LP  + P LCP  + GP  +P P +       E P +  ++
Sbjct: 711 ----PEDSLMSLPLEESPLLPLPEEPQLCP-RSEGPHLSPRPEEPHLSPRPEEPHLSPQA 765

Query: 777 PRSPRNNPVP---------------PEAKSPVLNPGERPADVSPTSPQPEGLLVLQQVGD 821
              P  +P P               P+A+ P L+P      +SP + +P    V ++   
Sbjct: 766 -EEPHLSPQPEEPCLCAVPEEPHLSPQAEGPHLSPQPEELHLSPQTEEPHLSPVPEEP-- 822

Query: 822 YCFLPGLGPGPLSLRSKPSSPGPGPEIKNLDQAFQVKKPPGQAVPQVPVIQLFKALKQQD 881
            C  P      LS +S+     P PE  +L    +++KPP    P+ P  +  +    ++
Sbjct: 823 -CLSPQPEESHLSPQSEEPCLSPRPEESHLSP--ELEKPPLSPRPEKPPEEPGQCPAPEE 879

Query: 882 YLSLPPWEVNKPGE 895
               PP     PGE
Sbjct: 880 LPLFPP-----PGE 888



 Score = 60.5 bits (145), Expect = 7e-09
 Identities = 107/406 (26%), Positives = 150/406 (36%), Gaps = 65/406 (16%)

Query: 491 SAELWPPGSMSAFTSGSPPHQGPWGSRFPELEGVFPVGFGDSEVSPLTIEDPKHVCDPPS 550
           ++ L PP   S  +   PP + P  S  PE   +FP  F +S +SP   E P  +  PP 
Sbjct: 569 ASRLSPPPEESPMSP--PPEESPM-SPPPEASRLFPP-FEESPLSPPPEESP--LSPPPE 622

Query: 551 GPDTTPAASDLPTEQPP--SPQPGPPAASHTP-------------EKQASSFDFNGPYLG 595
               +P   D P   PP  SP   PP  S                E   S      P   
Sbjct: 623 ASRLSPPPEDSPMSPPPEESPMSPPPEVSRLSPLPVVSRLSPPPEESPLSPPPEESPTSP 682

Query: 596 PPHSRSL--PDILGQPEPPQEGGSQKSPPPGSLEYL------CLPAGGQVQLVPLAQAMG 647
           PP +  L  P       PP E      PP  SL  L       LP   + QL P ++  G
Sbjct: 683 PPEASRLSPPPEDSPTSPPPEDSPASPPPEDSLMSLPLEESPLLPLPEEPQLCPRSE--G 740

Query: 648 PGQAVEVERRPSQGAAGSPSLESGGGPAPPALGPRVGGQDQKDSPVAIPMSSGDTEDPGV 707
           P  +   E          P L      +P A  P +  Q ++    A+P      E+P +
Sbjct: 741 PHLSPRPEEPHLSPRPEEPHL------SPQAEEPHLSPQPEEPCLCAVP------EEPHL 788

Query: 708 ASGYVSSADLVFTPNSGASSVSLVPS-LGL-PSDQTPSLCPGLASGPPGAPGPVKSGFEG 765
           +            P +    +S  P  L L P  + P L P +   P  +P P +S    
Sbjct: 789 S------------PQAEGPHLSPQPEELHLSPQTEEPHLSP-VPEEPCLSPQPEESHLSP 835

Query: 766 YVELPPIEGRSPRSPRNNPVPPEAKSPVLNP-GERPADVSPTSPQPEGLLVLQQVGDYCF 824
             E P +   SPR   ++ + PE + P L+P  E+P +     P PE L +    G+   
Sbjct: 836 QSEEPCL---SPRPEESH-LSPELEKPPLSPRPEKPPEEPGQCPAPEELPLFPPPGEPSL 891

Query: 825 LPGLGPGPLSLRSKPSSPGPGPEIKNLDQAFQVKKPPGQAVPQVPV 870
            P LG   LS   +P    P PE   L  + +    P Q +P  P+
Sbjct: 892 SPLLGEPALSEPGEPPL-SPLPEELPLSPSGEPSLSP-QLMPPDPL 935



 Score = 55.8 bits (133), Expect = 2e-07
 Identities = 88/366 (24%), Positives = 121/366 (33%), Gaps = 52/366 (14%)

Query: 531 DSEVSPLTIEDPKHVCDPPSGPDTTPAASDLPT--------------EQPPSPQPGPPAA 576
           +S +SP   E P     PP     +P   +LP               E P SP P     
Sbjct: 446 ESPLSPPPEESP--TSPPPEASRLSPPPEELPASPLPEALHLSRPLEESPLSPPPEESPL 503

Query: 577 SHTPEKQASSFDFNGPYLGPPHSRSLPDILGQPEPPQEGG--------SQKSPPPGSLEY 628
           S  PE    S     P   P  S   P +     PP E          S  SPPP  L  
Sbjct: 504 SPPPESSPFSPLEESPLSPPEESPPSPALETPLSPPPEASPLSPPFEESPLSPPPEELPT 563

Query: 629 LCLPAGGQVQLVPLAQAMGPGQAVEVERRPSQGAAGSPSLESGGGPAPP---ALGPRVGG 685
              P   ++   P    M P         P + +   P  E      PP    L P    
Sbjct: 564 SPPPEASRLSPPPEESPMSPPPEESPMSPPPEASRLFPPFEESPLSPPPEESPLSPPPEA 623

Query: 686 QDQKDSPVAIPMSSGDTEDPGVASGYVSSADLVFTPNSGASSVSLVPSLGLPSDQTPSLC 745
                 P   PMS    E P      VS            S + +V  L  P +++P   
Sbjct: 624 SRLSPPPEDSPMSPPPEESPMSPPPEVSR----------LSPLPVVSRLSPPPEESPLSP 673

Query: 746 PGLASGPPGAPGPVKSGFEGYVELPPIEGRSPRSPRNNPVPPEAKSPVLNPGERPADVSP 805
           P   S  P +P P  S     +  PP +  +   P ++P  P  +  +++    P + SP
Sbjct: 674 PPEES--PTSPPPEAS----RLSPPPEDSPTSPPPEDSPASPPPEDSLMS---LPLEESP 724

Query: 806 TSPQPEGLLVLQQVGDYCFLPGLGPGPLS--LRSKPSSPGPGPEIKNLDQAFQVKKPPGQ 863
             P PE      Q+      P L P P    L  +P  P   P+ +    + Q ++P   
Sbjct: 725 LLPLPEE----PQLCPRSEGPHLSPRPEEPHLSPRPEEPHLSPQAEEPHLSPQPEEPCLC 780

Query: 864 AVPQVP 869
           AVP+ P
Sbjct: 781 AVPEEP 786



 Score = 54.3 bits (129), Expect = 5e-07
 Identities = 90/331 (27%), Positives = 126/331 (38%), Gaps = 44/331 (13%)

Query: 507  SPPHQGPWGSRFPELEGVFPVGFGDSEVSPLTIEDPKHVCDPPSGPDTTPAA-----SDL 561
            SPP +    S  PE + +  +   +S + PL  E+P+ +C    GP  +P       S  
Sbjct: 699  SPPPEDSPASPPPE-DSLMSLPLEESPLLPLP-EEPQ-LCPRSEGPHLSPRPEEPHLSPR 755

Query: 562  PTEQPPSPQPGPPAASHTPEKQASSFDFNGPYLGPPHSRSLPDILGQPEP----PQEGGS 617
            P E   SPQ   P  S  PE+         P+L P      P +  QPE     PQ    
Sbjct: 756  PEEPHLSPQAEEPHLSPQPEEPCLCAVPEEPHLSPQAEG--PHLSPQPEELHLSPQTEEP 813

Query: 618  QKSPPPGSLEYLCL-PAGGQVQLVPLAQ--AMGPGQ-----AVEVERRPSQGAAGSPSLE 669
              SP P   E  CL P   +  L P ++   + P       + E+E+ P       P  E
Sbjct: 814  HLSPVP---EEPCLSPQPEESHLSPQSEEPCLSPRPEESHLSPELEKPPLSPRPEKPPEE 870

Query: 670  SGGGPAP-----------PALGPRVGGQDQKDSPVAIPMSSGDTEDPGVASGYVSSADLV 718
             G  PAP           P+L P +G +     P   P+S    E P   SG  S +  +
Sbjct: 871  PGQCPAPEELPLFPPPGEPSLSPLLG-EPALSEPGEPPLSPLPEELPLSPSGEPSLSPQL 929

Query: 719  FTPNSGASSVSLVPSLGLPSDQTPSLCP-GLASGPPGAPGPVKSGFEGYVELPPIEGRSP 777
              P+     +S + +   P    P+L P G    P GA G   S  E  +  P +E    
Sbjct: 930  MPPDPLPPPLSPIITAAAP----PALSPLGELEYPFGAKGD--SDPESPLAAPILETPIS 983

Query: 778  RSPRNNPVPPEAKSPVLNPGERPADVSPTSP 808
              P  N   PE   P++ P    + V P SP
Sbjct: 984  PPPEANCTDPEPVPPMILPPSPGSPVGPASP 1014



 Score = 51.2 bits (121), Expect = 4e-06
 Identities = 87/342 (25%), Positives = 118/342 (34%), Gaps = 75/342 (21%)

Query: 502  AFTSGSPPHQGPWGSRFPELEGVFPVGFGDSEVSPLTIEDPKHVCDPPSGPD-------- 553
            AF +GS  H       FP      P G   ++V   + + P  V  P +G          
Sbjct: 2478 AFKAGSLAHTSLGAGGFPAALPAGPAGELHAKVP--SGQPPNFVRSPGTGAFVGTPSPMR 2535

Query: 554  -TTPAASDLPTEQPPSPQPGPPAASHTPEKQASSFDFNGPYLGPPHSRSLPDILGQPEPP 612
             T P A   P+ +PP PQPG P     P    +S    GP LG P S +     G   P 
Sbjct: 2536 FTFPQAVGEPSLKPPVPQPGLP-----PPHGINSHFGPGPTLGKPQSTNYTVATGNFHP- 2589

Query: 613  QEGGSQKSPPPGSLEYLCLPAGGQVQLVPLAQAMGPGQAVEVERRPSQGAAGSPSLESGG 672
               GS   P  GS        G    L PL              RP       PS+    
Sbjct: 2590 --SGSPLGPSSGS-------TGESYGLSPL--------------RP-------PSVLPP- 2618

Query: 673  GPAPPALGPRVGGQDQKDSPVAIPMSSGDTEDPGVASGY-VSSADLVFTPNSGASSVSL- 730
             PAP    P +     + S +  P+     EDPG   G  +++A+L  T + G S +S  
Sbjct: 2619 -PAPDGSLPYLSHGASQRSGITSPVEK--REDPGTGMGSSLATAELPGTQDPGMSGLSQT 2675

Query: 731  -------------------VPSLGLPSDQTPSLCPGLASGPPGAPG--PVKSGFEGYVE- 768
                               +    L  ++  +     A GPPG+ G  P    FE     
Sbjct: 2676 ELEKQRQRQRLRELLIRQQIQRNTLRQEKETAAAAAGAVGPPGSWGAEPSSPAFEQLSRG 2735

Query: 769  LPPIEGRSPRSPRNNPVPPEAKSPVLNPGERPADVSPTSPQP 810
              P  G   +S      P +   P+L PG  P+D   + P P
Sbjct: 2736 QTPFAGTQDKSSLVGLPPSKLSGPILGPGSFPSDDRLSRPPP 2777



 Score = 47.4 bits (111), Expect = 6e-05
 Identities = 105/401 (26%), Positives = 142/401 (35%), Gaps = 99/401 (24%)

Query: 556  PAASDLPTEQPPSPQPGPPAASHTPEKQASSFDFNGPYLGPPHSRSLPDILGQPEP-PQE 614
            PA S   TE P + Q GP A   TPE  A+        + P  S     +L QP+P PQ 
Sbjct: 4031 PAVSSEATEGPSTHQGGPLAIGTTPESMAT----EPGEVKPSLSGDSQLLLVQPQPQPQP 4086

Query: 615  GGSQKSPP---PGSLEY---LCLPAGG------------QVQLVP--LAQ---AMG--PG 649
               Q  PP   PG  +    L   AGG            +   VP  LAQ   ++G  PG
Sbjct: 4087 SSLQLQPPLRLPGQQQQQVSLLHTAGGGSHGQLGSGSSSEASSVPHLLAQPSVSLGDQPG 4146

Query: 650  QAVEVERRPSQGAAGSPSLESGGGPAPPALGPRV-GGQDQKDSPVAIPMSSGDTEDPGVA 708
               +    P Q     P +++  GP PP  GP +  GQ      +   +     +  GV 
Sbjct: 4147 SMTQNLLGPQQPMLERP-MQNNTGPQPPKPGPVLQSGQGLPGVGIMPTVGQLRAQLQGVL 4205

Query: 709  SGYVS------------SADLVFTPNSGASSVSLVPSLGLPSDQTPSL------------ 744
            +                 A L+      + +V   P    P  QT  L            
Sbjct: 4206 AKNPQLRHLSPQQQQQLQALLMQRQLQQSQAVRQTPPYQEPGTQTSPLQGLLGCQPQLGG 4265

Query: 745  CPGLASGP----------------PGAPGPVKSG---FEGYVELPPIEGRSPRSPRNNP- 784
             PG  +GP                P  PG + +G      +   PP   + P+ P   P 
Sbjct: 4266 FPGPQTGPLQELGAGPRPQGPPRLPAPPGALSTGPVLGPVHPTPPPSSPQEPKRPSQLPS 4325

Query: 785  ----VPPEAKSPVLNPGERPADVSPTSPQPEGLL--VLQQVGDYCFLPGLG----PGPLS 834
                +P EA+ P  +PG  P    PT   P G +     Q+ D  F  GLG    P  L+
Sbjct: 4326 PSSQLPTEAQLPPTHPG-TPKPQGPTLEPPPGRVSPAAAQLADTLFSKGLGPWDPPDNLA 4384

Query: 835  LRSKP--SSPGPGPEIKNLDQAFQVKKPPGQAVPQVPVIQL 873
               KP  SS  PG    +LDQ        GQ VP+   + +
Sbjct: 4385 ETQKPEQSSLVPG----HLDQV------NGQVVPEASQLSI 4415



 Score = 39.7 bits (91), Expect = 0.013
 Identities = 75/291 (25%), Positives = 102/291 (35%), Gaps = 63/291 (21%)

Query: 612 PQEGGSQKSPPPGSLEYLCL--PAGGQVQLVPLAQAMGPGQAVEVERRPSQGAAG---SP 666
           P E G   +  P +L   C   P GG V  +   Q   PG  ++ E +P  G AG    P
Sbjct: 374 PPEPGDTPTDEPDALYVACQGQPKGGHVTSM---QPKEPGP-LQCEAKPL-GKAGVQLEP 428

Query: 667 SLESGGGPAPPALGPRVGGQDQKDSPVAIPMSSGDTEDPGVASGYVSSADLVFTPNSGAS 726
            LE+      P L P       ++SP++ P     T  P  AS                 
Sbjct: 429 QLEAPLNEEMPLLPP------PEESPLSPPPEESPTSPPPEAS----------------- 465

Query: 727 SVSLVPSLGLPSDQTPSLCPGLASGPPGAPGPVKSGFEGYVELPPIEGRSPRSPRNNPVP 786
                  L  P ++ P      AS  P A    +   E  +  PP E      P ++P  
Sbjct: 466 ------RLSPPPEELP------ASPLPEALHLSRPLEESPLSPPPEESPLSPPPESSPFS 513

Query: 787 PEAKSPVLNPGE---RPADVSPTSPQPEGLLVLQQVGDYCFLPGLGPGPLSLRSKPSSPG 843
           P  +SP+  P E    PA  +P SP PE   +          P     PLS   +     
Sbjct: 514 PLEESPLSPPEESPPSPALETPLSPPPEASPL---------SPPFEESPLSPPPEELPTS 564

Query: 844 PGPEIKNLDQAFQVK--KPPGQAVPQVP---VIQLFKALKQQDYLSLPPWE 889
           P PE   L    +     PP +  P  P     +LF   ++   LS PP E
Sbjct: 565 PPPEASRLSPPPEESPMSPPPEESPMSPPPEASRLFPPFEESP-LSPPPEE 614



 Score = 37.0 bits (84), Expect = 0.082
 Identities = 81/297 (27%), Positives = 110/297 (37%), Gaps = 36/297 (12%)

Query: 571  PGPPAASHTPEKQASSFDFNGPYLGPPHSRSLPDILGQPEPPQEGGSQKSPP-PGSLEYL 629
            P  P A  +P   A+   F G    P    +  D  G  +PP   GS   P  PG L +L
Sbjct: 2107 PPQPGALGSPPPAAAPTIFIGSPTTPAGLSTSAD--GFLKPP--AGSVPGPDSPGEL-FL 2161

Query: 630  CLPAGGQVQLVPLAQAMGPGQAVEVERR-PSQGAAGSPSLESGGGPA-PPALG----PRV 683
             LP     Q VP     G   A  +E R P+      P     G PA PP LG    P  
Sbjct: 2162 KLPPQVPAQ-VPSQDPFGLAPAYPLEPRFPTAPPTYPPYPSPTGAPAQPPMLGASSRPGA 2220

Query: 684  GGQDQ-KDSPVAIPMSSGDTEDPGVASGYVSSADLVFTPNSG-----ASSVSLVP----- 732
            G   +   +P   P     T DP +     S  +L    + G     AS   L P     
Sbjct: 2221 GQPGEFHTTPPGTPRHQPSTPDPFLKPRCPSLDNLAVPESPGVGGGKASEPLLSPPPFGE 2280

Query: 733  ---SLGLPSDQTPSLCPGLASGPPG---APGPVKSGFEGYVELP-PIEGRSPRSPRNNPV 785
               +L +  ++  +  P    GPP       P      G +EL  P   ++P +PR + V
Sbjct: 2281 SRKALEVKKEELGASSPSY--GPPNLGFVDSPSSGTHLGGLELKTPDVFKAPLTPRASQV 2338

Query: 786  PPEAKSPVLNPGERPADVSPTSPQPEGLLVLQQVGDYCFLPGLGPGPLSLRSKPSSP 842
             P++    L P E P      +P P     + + G Y   P   P PL+ R +P  P
Sbjct: 2339 EPQSPGLGLRPQE-PPPAQALAPSPPSHPDIFRPGSYTD-PYAQP-PLTPRPQPPPP 2392



 Score = 35.4 bits (80), Expect = 0.24
 Identities = 49/176 (27%), Positives = 64/176 (36%), Gaps = 26/176 (14%)

Query: 508  PPHQGPWGSRFPELEGVFPVGFGDSEVSPL----TIEDPKHVCDPPSGPDTTPAASDLPT 563
            P  QGP   R P   G    G     V P     + ++PK     PS     P  + LP 
Sbjct: 4281 PRPQGP--PRLPAPPGALSTGPVLGPVHPTPPPSSPQEPKRPSQLPSPSSQLPTEAQLPP 4338

Query: 564  EQPPSPQP-----GPPAASHTPEKQASSFDFNGPYLGPPHSRSLPDILGQPEPPQEGGSQ 618
              P +P+P      PP    +P     +       LGP      PD L + + P+    Q
Sbjct: 4339 THPGTPKPQGPTLEPPPGRVSPAAAQLADTLFSKGLGP---WDPPDNLAETQKPE----Q 4391

Query: 619  KSPPPGSLEYLCLPAGGQVQLVPLAQAMGPGQAVEVERRPSQGAAGSPSLESGGGP 674
             S  PG L+ +     GQV  VP A  +   Q  E    P    A S   E+ G P
Sbjct: 4392 SSLVPGHLDQV----NGQV--VPEASQLSIKQ--EPREEPCALGAQSVKREANGEP 4439



 Score = 34.3 bits (77), Expect = 0.53
 Identities = 54/228 (23%), Positives = 84/228 (36%), Gaps = 36/228 (15%)

Query: 686  QDQKDSPVAIPMSSGDTEDPGVASGYVSSADLVFTPNSGASSVSLVPSLGLPSDQTPSLC 745
            Q  KD+  A  ++    +     +      D+    +  A  + + P  G      P+  
Sbjct: 2062 QKAKDNRAAHRINKVQKQAESQINKQTKVGDIARKTDRPALHLRIPPQPGALGSPPPAAA 2121

Query: 746  PGLASGPPGAPGPVKSGFEGYVELPPIEGRSPRSPRN--NPVPPE--AKSPVLNP-GERP 800
            P +  G P  P  + +  +G+++ P      P SP      +PP+  A+ P  +P G  P
Sbjct: 2122 PTIFIGSPTTPAGLSTSADGFLKPPAGSVPGPDSPGELFLKLPPQVPAQVPSQDPFGLAP 2181

Query: 801  A-----------DVSPTSPQPEGLLVLQQVGDYCFLPGLG-PG------PLSLRSKPSSP 842
            A              P  P P G      +      PG G PG      P + R +PS+P
Sbjct: 2182 AYPLEPRFPTAPPTYPPYPSPTGAPAQPPMLGASSRPGAGQPGEFHTTPPGTPRHQPSTP 2241

Query: 843  GP--GPEIKNLDQAFQVKKPPGQAVPQVPVIQLFKALKQQDYLSLPPW 888
             P   P   +LD           AVP+ P +   KA   +  LS PP+
Sbjct: 2242 DPFLKPRCPSLDNL---------AVPESPGVGGGKA--SEPLLSPPPF 2278



 Score = 30.4 bits (67), Expect = 7.7
 Identities = 50/215 (23%), Positives = 73/215 (33%), Gaps = 18/215 (8%)

Query: 501  SAFTSGSPPHQGPWGSR-----FPELEGVFPVGFGDSEVSPLTIEDPKHVCDPPSGPDTT 555
            +A  +G+    G WG+      F +L        G  + S L    P  +  P  GP + 
Sbjct: 2707 AAAAAGAVGPPGSWGAEPSSPAFEQLSRGQTPFAGTQDKSSLVGLPPSKLSGPILGPGSF 2766

Query: 556  PAASDLPTEQPPSPQPGPPAASHTPEKQASSFDFNGPYLGPPHSRSLPDILGQPEPPQEG 615
            P+   L    PP+        S      + +F    PY G    +     L Q +     
Sbjct: 2767 PSDDRLSRPPPPATPSSMDVNSRQLVGGSQAFYQRAPYPGSLPLQQQQQQLWQQQQATAA 2826

Query: 616  GSQKSPPPGSLEYLCLPAGGQVQL-VPLA----QAMGPGQAVEVERRPSQGAAGSPSLES 670
             S +            P  G+  L  PLA    +  GPG+ V     P+Q      +++ 
Sbjct: 2827 TSMRFAMSARFPSTPGPELGRQALGSPLAGISTRLPGPGEPVPGPAGPAQFIELRHNVQK 2886

Query: 671  GGGPAPPALGPRVGGQDQKDSPVAIPMSSGDTEDP 705
            G GP     G    GQ     P   P+S    EDP
Sbjct: 2887 GLGPG----GTPFPGQGPPQRPRFYPVS----EDP 2913



 Score = 30.4 bits (67), Expect = 7.7
 Identities = 28/112 (25%), Positives = 43/112 (38%), Gaps = 31/112 (27%)

Query: 519  PELEGVFPVGFGDSEVSPLTIEDPKHVCDPPSGPDTTPAAS------DLPTE---QPPSP 569
            P  +  +     + +V  L+   P+    PPS    +PA+       +LPTE   +PP P
Sbjct: 4888 PPTQHSYTYNVSNLDVRQLSAPPPEEPSPPPSPLAPSPASPPTEPLVELPTEPLAEPPVP 4947

Query: 570  QPGPPAASHTPEKQASSFDFNGPYLGPPHSRSLPDILGQPEPPQEGGSQKSP 621
             P P A+S                  P  +R  P    +  PP+EG   + P
Sbjct: 4948 SPLPLASS------------------PESARPKP----RARPPEEGEDSRPP 4977


>gi|19924097 synapsin I isoform Ib [Homo sapiens]
          Length = 669

 Score = 68.9 bits (167), Expect = 2e-11
 Identities = 77/276 (27%), Positives = 92/276 (33%), Gaps = 63/276 (22%)

Query: 549 PSGPDTTPAASDLPTEQPPSPQPGPPAASHTPEKQASSFDFNGP--------YLGPPHSR 600
           P G  T+   +  P +Q P PQ GPP     P++Q        P         LGPP   
Sbjct: 443 PLGRQTSQQPAGPPAQQRPPPQGGPPQPGPGPQRQGPPLQQRPPPQGQQHLSGLGPPAGS 502

Query: 601 SLPDILGQP-EPPQEGGSQKSPPPGSLEYLCLPAGGQVQLVPLAQAMGPGQAVEVERRPS 659
            LP  L  P   PQ+  SQ +PP           G   Q  P+A   G   A      PS
Sbjct: 503 PLPQRLPSPTSAPQQPASQAAPP---------TQGQGRQSRPVAGGPGAPPAARPPASPS 553

Query: 660 -QGAAGSPSL---ESGGGPAPP-ALGPRVGGQDQKDSPVAIPMSSGDTEDPGVASGYVSS 714
            Q  AG P      S  GPAPP A G   GGQ ++  P   P  +G              
Sbjct: 554 PQRQAGPPQATRQTSVSGPAPPKASGAPPGGQQRQGPPQKPPGPAG-------------- 599

Query: 715 ADLVFTPNSGASSVSLVPSLGLPSDQTPSLCPGLASGPPGAPGPVKSGFEGYVELPPIEG 774
                 P   AS    VP  G P+ Q P          P  PGP         + P    
Sbjct: 600 ------PTRQASQAGPVPRTGPPTTQQPR---------PSGPGPAGRPKPQLAQKP---- 640

Query: 775 RSPRSPRNNPVPPEAKSPVLNPGERPADVSPTSPQP 810
                  +  VPP A +    P       SP   QP
Sbjct: 641 -------SQDVPPPATAAAGGPPHPQLKASPAQAQP 669



 Score = 33.9 bits (76), Expect = 0.70
 Identities = 48/194 (24%), Positives = 65/194 (33%), Gaps = 29/194 (14%)

Query: 681 PRVGGQDQKDSPVAIPMSSGDTEDPGVASGYVSSADLVFTPNSGASSVSLVPSLGL-PSD 739
           P  G   Q  SP A+P+    ++ P               P  G       P L   P  
Sbjct: 428 PGRGSHGQTPSPGALPLGRQTSQQPAGPPAQQRPPPQGGPPQPGPGPQRQGPPLQQRPPP 487

Query: 740 QTPSLCPGLASGPP-GAPGPVKSGFEGYVELPPIEGRSPRSPRNNPVPP------EAKSP 792
           Q      GL  GPP G+P P +          P    +P+ P +   PP      +++  
Sbjct: 488 QGQQHLSGL--GPPAGSPLPQRL---------PSPTSAPQQPASQAAPPTQGQGRQSRPV 536

Query: 793 VLNPGERPADVSPTSPQPEGLLVLQQVGDYCFLPGLGPGPLSLRSKPSSPGPGPEIKNLD 852
              PG  PA   P SP P+      Q      + G  P       K S   PG +     
Sbjct: 537 AGGPGAPPAARPPASPSPQRQAGPPQATRQTSVSGPAP------PKASGAPPGGQ----Q 586

Query: 853 QAFQVKKPPGQAVP 866
           +    +KPPG A P
Sbjct: 587 RQGPPQKPPGPAGP 600


>gi|4502951 collagen type III alpha 1 preproprotein [Homo sapiens]
          Length = 1466

 Score = 67.8 bits (164), Expect = 4e-11
 Identities = 102/383 (26%), Positives = 129/383 (33%), Gaps = 74/383 (19%)

Query: 505  SGSPPHQGPWGSRFPELEGVFPVGFGDSEVSPLTIEDPKHVCDPPSGPDT--TPAASDLP 562
            +G+P  +GP     P L G   +  G     P   E  K    PP  P    TP    +P
Sbjct: 677  AGAPGERGP-----PGLAGAPGLRGGAGPPGP---EGGKGAAGPPGPPGAAGTPGLQGMP 728

Query: 563  TEQ----PPSP-----QPGPPAASHTPEKQASSFDFNGPYLGPPHSRSLPDILGQPEPPQ 613
             E+     P P     +PG P A   P K       +GP  GP      P   GQP    
Sbjct: 729  GERGGLGSPGPKGDKGEPGGPGADGVPGK-------DGPR-GPTGPIGPPGPAGQPGDKG 780

Query: 614  EGGSQKSP----PPGSLEYLCLPAGGQVQLVPLAQAMGPGQAVEVERRPSQGAAGSPSLE 669
            EGG+   P    P GS        G + +  P   A  PG   +      +G  G+P  +
Sbjct: 781  EGGAPGLPGIAGPRGS-------PGERGETGPPGPAGFPGAPGQNGEPGGKGERGAPGEK 833

Query: 670  SGGGPAPPALGPRVGGQDQKDSPVAIPMSSGDTEDPGVASGYVSSADLVFTPNSGASSVS 729
              GGP   A  P   G      P  +    G    PG A+G+  +  L   P S  +   
Sbjct: 834  GEGGPPGVAGPPGGSGPAGPPGPQGVKGERGSPGGPG-AAGFPGARGLPGPPGSNGNPGP 892

Query: 730  LVPSLGLPSDQTPSLC--------PGL-----------------ASGPPGAPGPVK---- 760
              PS     D  P           PG+                 A GPPGAPGP+     
Sbjct: 893  PGPSGSPGKDGPPGPAGNTGAPGSPGVSGPKGDAGQPGEKGSPGAQGPPGAPGPLGIAGI 952

Query: 761  SGFEGYVELPPIEGRSPRSPRNNPVPPEAKSPVLNPGERPADVSPTSPQPEGLLVLQQVG 820
            +G  G    P + G     PR +P P   K     PG          P P+GL  L    
Sbjct: 953  TGARGLAGPPGMPG-----PRGSPGPQGVKGESGKPGANGLSGERGPPGPQGLPGLAGTA 1007

Query: 821  DYCFLPGLGPGPLSLRSKPSSPG 843
                  G  PG   L  +  SPG
Sbjct: 1008 GEPGRDG-NPGSDGLPGRDGSPG 1029



 Score = 58.9 bits (141), Expect = 2e-08
 Identities = 99/385 (25%), Positives = 126/385 (32%), Gaps = 70/385 (18%)

Query: 496 PPGSMSAFTSGSPPHQGPWGSRFPELEGVFPVGFGDSEVSPLTIEDPKHVCDPPSGPDTT 555
           PPGS     SG P   GP G R       FP   G+        E        P GP   
Sbjct: 553 PPGSQGE--SGRPGPPGPSGPRGQPGVMGFPGPKGNDGAPGKNGERGGPGGPGPQGP--- 607

Query: 556 PAASDLPTEQPPSPQPGPPAASHTPEKQASSFDFNGPYLGPPHSRSLPDILGQPEPPQEG 615
                 P +   +   GPP  +     +  +        GPP  + L  + G   PP E 
Sbjct: 608 ------PGKNGETGPQGPPGPTGPGGDKGDT--------GPPGPQGLQGLPGTGGPPGEN 653

Query: 616 GSQKSPPPGSLEYLCLPAGGQVQLVPLAQAMGPGQAVEVERRPSQGAAGSPSLESGGGPA 675
           G    P P          GG+        A  PG+      R   G AG+P L  G GP 
Sbjct: 654 GKPGEPGPKGDAGAPGAPGGK------GDAGAPGE------RGPPGLAGAPGLRGGAGPP 701

Query: 676 PPALG---------------PRVGGQDQKDSPVAIPMSSGDTEDP-GVASGYVSSADLVF 719
            P  G               P + G   +   +  P   GD  +P G  +  V   D   
Sbjct: 702 GPEGGKGAAGPPGPPGAAGTPGLQGMPGERGGLGSPGPKGDKGEPGGPGADGVPGKD--- 758

Query: 720 TPNSGASSVSLVPSLGLPSDQTPSLCPGL--ASGPPGAPGPVKSGFEGYVELPPIEGRSP 777
            P      +      G P D+     PGL   +GP G+PG  + G  G    PP     P
Sbjct: 759 GPRGPTGPIGPPGPAGQPGDKGEGGAPGLPGIAGPRGSPG--ERGETG----PPGPAGFP 812

Query: 778 RSPRNNPVPPEAKSPVLNPGERPADVSPTSPQPEGLLVLQQVGDYCFLPGLGPGPLSLRS 837
            +P  N   P  K     PGE+     P    P G       G     P   PGP  ++ 
Sbjct: 813 GAPGQNG-EPGGKGERGAPGEKGEGGPPGVAGPPG-------GSG---PAGPPGPQGVKG 861

Query: 838 KPSSPGPGPEIKNLDQAFQVKKPPG 862
           +  SPG GP       A  +  PPG
Sbjct: 862 ERGSPG-GPGAAGFPGARGLPGPPG 885



 Score = 58.2 bits (139), Expect = 3e-08
 Identities = 87/341 (25%), Positives = 106/341 (31%), Gaps = 53/341 (15%)

Query: 549 PSGPDTTPAASDLPTEQPPSPQPGPPAASHTPEKQASSFDFNGP-YLGPPHSRSLPDILG 607
           P G    P     P E     +PGP   +  P       D   P   GPP     P + G
Sbjct: 637 PQGLQGLPGTGGPPGENGKPGEPGPKGDAGAPGAPGGKGDAGAPGERGPPGLAGAPGLRG 696

Query: 608 QPEPP-QEGGSQKSPPPGSLEYLCLPAGGQVQLVPLAQAMGPGQAVEVERRPSQGAAGSP 666
              PP  EGG   + PPG       P G Q           PG   +       GA G P
Sbjct: 697 GAGPPGPEGGKGAAGPPGPPGAAGTP-GLQGMPGERGGLGSPGPKGDKGEPGGPGADGVP 755

Query: 667 SLESGGGPAPPALGPRVGGQ--DQKDS----------PVAIPMSSGDTEDPGVASGYVSS 714
             +   GP  P   P   GQ  D+ +           P   P   G+T  PG A G+  +
Sbjct: 756 GKDGPRGPTGPIGPPGPAGQPGDKGEGGAPGLPGIAGPRGSPGERGETGPPGPA-GFPGA 814

Query: 715 ADLVFTPNSGASSVSLVPSLGLPSDQTPSLCPGLA-----SGPPGAPGPVKSGFEGYVEL 769
                 P             G P ++     PG+A     SGP G PGP   G +G    
Sbjct: 815 PGQNGEPGGKGER-------GAPGEKGEGGPPGVAGPPGGSGPAGPPGP--QGVKGERGS 865

Query: 770 PPIEGRSP-RSPRNNPVPPEAKSPVLNPGERPADVSPTSPQPEGLLVLQQVGDYCFLPGL 828
           P   G +     R  P PP +     NPG      SP    P                  
Sbjct: 866 PGGPGAAGFPGARGLPGPPGSNG---NPGPPGPSGSPGKDGP------------------ 904

Query: 829 GPGPLSLRSKPSSPGPGPEIKNLDQAFQVKKPPGQAVPQVP 869
            PGP      P SPG      +  Q  +   P  Q  P  P
Sbjct: 905 -PGPAGNTGAPGSPGVSGPKGDAGQPGEKGSPGAQGPPGAP 944



 Score = 55.1 bits (131), Expect = 3e-07
 Identities = 100/356 (28%), Positives = 131/356 (36%), Gaps = 56/356 (15%)

Query: 567 PSPQPGPPAASHTPEKQASSFDFNGPYLGPPHSRSLPDILGQPEPPQEGGSQKSP-PPGS 625
           P P PGPP  +  P    +  +  GP  G P S   P   G+P P    G+Q  P PPG 
Sbjct: 332 PGP-PGPPGTAGFPGSPGAKGEV-GP-AGSPGSNGAPGQRGEPGPQGHAGAQGPPGPPG- 387

Query: 626 LEYLCLPAGGQVQLVPLAQAMGPGQAVEVERRPSQGAAGSPSLESGGGP-----APPALG 680
              +    GG+ ++ P      PG           GA G+P L  G G      A    G
Sbjct: 388 ---INGSPGGKGEMGPAGIPGAPGLMGARGPPGPAGANGAPGLRGGAGEPGKNGAKGEPG 444

Query: 681 PRVGGQDQKDSPVAIPMSSGD------TEDPGVASGYVSSADLVFTPN-SGASSVSLVPS 733
           PR  G+  +     +P + G+        +PG A+G   +A     P   G +  + +P 
Sbjct: 445 PR--GERGEAGIPGVPGAKGEDGKDGSPGEPG-ANGLPGAAGERGAPGFRGPAGPNGIPG 501

Query: 734 LGLPSDQTPSLCPGLASGPPGAPG-PVKSGFEGYVELPPIEGRSPRSPRNNPVPPEAKSP 792
              P+ +  +  PG A GP GA G P + G  G        G   R    +P  P +   
Sbjct: 502 EKGPAGERGA--PGPA-GPRGAAGEPGRDGVPG--------GPGMRGMPGSPGGPGSDGK 550

Query: 793 VLNPGERPADVSPTSPQPEGLLVLQQVGDYCFLPGL-----GPGPLSLRSKPSSPGP-GP 846
              PG +     P  P P G     Q G   F PG       PG    R  P  PGP GP
Sbjct: 551 PGPPGSQGESGRPGPPGPSG--PRGQPGVMGF-PGPKGNDGAPGKNGERGGPGGPGPQGP 607

Query: 847 EIKNLDQAFQVKKPP-------GQAVPQVPVIQLFKALKQQDYLSLPPWEVNKPGE 895
             KN +   Q    P       G   P  P     + L+       PP E  KPGE
Sbjct: 608 PGKNGETGPQGPPGPTGPGGDKGDTGPPGP-----QGLQGLPGTGGPPGENGKPGE 658



 Score = 50.8 bits (120), Expect = 6e-06
 Identities = 110/430 (25%), Positives = 142/430 (33%), Gaps = 116/430 (26%)

Query: 488  QNGSAELWPPGSMSAFTS----GSPPHQGPWGSRFPELEGVFPVGFGDSEVSPLTIEDPK 543
            + G     PPG   A  +    G P  +G  GS  P+ +   P G G   V     + P+
Sbjct: 704  EGGKGAAGPPGPPGAAGTPGLQGMPGERGGLGSPGPKGDKGEPGGPGADGVPGK--DGPR 761

Query: 544  HVCDPPSGPDTTPAASDLPTEQPPSPQPGPPAASH---TPEKQASSFDFNGPYLGPPHSR 600
                 P+GP   P  +  P ++     PG P  +    +P ++  +        GPP   
Sbjct: 762  G----PTGPIGPPGPAGQPGDKGEGGAPGLPGIAGPRGSPGERGET--------GPPGPA 809

Query: 601  SLPDILGQPEPPQEGGSQKSP-------PPGSLEYLCLPAGGQVQLVPLAQAMGPG-QAV 652
              P   GQ   P   G + +P       PPG    +  P GG     P      PG Q V
Sbjct: 810  GFPGAPGQNGEPGGKGERGAPGEKGEGGPPG----VAGPPGGSGPAGP------PGPQGV 859

Query: 653  EVERRP--SQGAAGSPSLE-------SGGGPAPPALGPRVGGQDQKDSPVAIPMSSGDTE 703
            + ER      GAAG P          S G P PP  GP   G   KD P     ++G   
Sbjct: 860  KGERGSPGGPGAAGFPGARGLPGPPGSNGNPGPP--GP--SGSPGKDGPPGPAGNTGAPG 915

Query: 704  DPGVASGYVSSADLVFTPNSGASSVSLVPSLGLPSDQTPSLCPGLA-----------SGP 752
             PGV+            P   A         G P  Q P   PG             +GP
Sbjct: 916  SPGVSG-----------PKGDAGQPG---EKGSPGAQGPPGAPGPLGIAGITGARGLAGP 961

Query: 753  PGAPGPVKS----GFEGYVELPPIEG----RSPRSPRNNP-------------------V 785
            PG PGP  S    G +G    P   G    R P  P+  P                   +
Sbjct: 962  PGMPGPRGSPGPQGVKGESGKPGANGLSGERGPPGPQGLPGLAGTAGEPGRDGNPGSDGL 1021

Query: 786  PPEAKSPVLNPGERPADVSPTSPQPEG-------LLVLQQVGDYCFL----PGLGPGPLS 834
            P    SP    G+R  + SP +P   G       +    + GD        P   PGP  
Sbjct: 1022 PGRDGSPG-GKGDRGENGSPGAPGAPGHPGPPGPVGPAGKSGDRGESGPAGPAGAPGPAG 1080

Query: 835  LRSKPSSPGP 844
             R  P   GP
Sbjct: 1081 SRGAPGPQGP 1090



 Score = 43.9 bits (102), Expect = 7e-04
 Identities = 75/265 (28%), Positives = 87/265 (32%), Gaps = 35/265 (13%)

Query: 569 PQPGPPAASHTPEKQASSFDFNGPYLGPPHSRSLPDILGQPEPPQEGGSQKSP-PPGSLE 627
           PQP P A +  P  Q        P  GPP    +P   G P  P + GS  SP PPG  E
Sbjct: 89  PQP-PTAPTRPPNGQGPQGPKGDP--GPP---GIPGRNGDPGIPGQPGSPGSPGPPGICE 142

Query: 628 YLCLPAGGQVQLVPLAQAMGPGQAVEVERRPSQ-GAAGSPSLESGGGPAPPALGPRVG-- 684
               P G Q    P   +      V V       G AG P     G P PP      G  
Sbjct: 143 --SCPTGPQ-NYSPQYDSYDVKSGVAVGGLAGYPGPAGPP-----GPPGPPGTSGHPGSP 194

Query: 685 GQDQKDSPVAIPMSSGDTEDPGVASGYVSSADLVFTPNSGASSVSLVPSL-GLPSDQTPS 743
           G      P   P  +G +  PG       S        SG         L G P  + P+
Sbjct: 195 GSPGYQGPPGEPGQAGPSGPPGPPGAIGPSGPAGKDGESGRPGRPGERGLPGPPGIKGPA 254

Query: 744 LCPGLAS--------------GPPGAPG-PVKSGFEGYVELP-PIEGRSPRSPRNNPVPP 787
             PG                 G  GAPG   ++G  G    P P+  R     R  P  P
Sbjct: 255 GIPGFPGMKGHRGFDGRNGEKGETGAPGLKGENGLPGENGAPGPMGPRGAPGERGRPGLP 314

Query: 788 EAKSPVLNPGERPADVSPTSPQPEG 812
            A     N G R +D  P  P P G
Sbjct: 315 GAAGARGNDGARGSDGQPGPPGPPG 339



 Score = 40.8 bits (94), Expect = 0.006
 Identities = 85/354 (24%), Positives = 108/354 (30%), Gaps = 76/354 (21%)

Query: 549 PSGPDTTPAASDLPTEQPPSPQPGPPAASHTP----------------EKQASSFDF-NG 591
           P GP   P    +P        PG P +  +P                  Q  S+D  +G
Sbjct: 104 PQGPKGDPGPPGIPGRNGDPGIPGQPGSPGSPGPPGICESCPTGPQNYSPQYDSYDVKSG 163

Query: 592 PYLGPPHSRSLPDILGQPEPPQEGGSQKSP-PPGSLEYLCLPAGGQVQLVPLAQAMGPGQ 650
             +G       P   G P PP   G+   P  PGS  Y   P               PGQ
Sbjct: 164 VAVG--GLAGYPGPAGPPGPPGPPGTSGHPGSPGSPGYQGPPG-------------EPGQ 208

Query: 651 AVEVERRPSQGAAGSPSLESGGGPAPPALGPRVGGQDQKDSPVAIPMSSGDTEDPGVASG 710
           A         G +G P      GP+ PA      G+  +     +P   G     G+   
Sbjct: 209 A---------GPSGPPGPPGAIGPSGPAGKDGESGRPGRPGERGLPGPPGIKGPAGIPGF 259

Query: 711 YVSSADLVFTPNSGASSVSLVPSL----GLPSDQTPSLCPGLASGPPGAPG-------PV 759
                   F   +G    +  P L    GLP +      PG   GP GAPG       P 
Sbjct: 260 PGMKGHRGFDGRNGEKGETGAPGLKGENGLPGENG---APG-PMGPRGAPGERGRPGLPG 315

Query: 760 KSGFEGYVELPPIEGR----SPRSPRNNPVPPEAK---SPVLNPGERPADVSPTSPQPEG 812
            +G  G       +G+     P      P  P AK    P  +PG   A      P P+G
Sbjct: 316 AAGARGNDGARGSDGQPGPPGPPGTAGFPGSPGAKGEVGPAGSPGSNGAPGQRGEPGPQG 375

Query: 813 LLVLQQVGDYCFLPGLGPGPLSLRSKPSSPGP-GPE-IKNLDQAFQVKKPPGQA 864
               Q            PGP  +   P   G  GP  I         + PPG A
Sbjct: 376 HAGAQG----------PPGPPGINGSPGGKGEMGPAGIPGAPGLMGARGPPGPA 419



 Score = 39.3 bits (90), Expect = 0.017
 Identities = 69/280 (24%), Positives = 78/280 (27%), Gaps = 77/280 (27%)

Query: 491  SAELWPPGSMS----AFTSGSPPHQG-PWGSRFPELEGVFPVGFGD--SEVSPLTIEDPK 543
            S E  PPG       A T+G P   G P     P  +G  P G GD     SP     P 
Sbjct: 989  SGERGPPGPQGLPGLAGTAGEPGRDGNPGSDGLPGRDGS-PGGKGDRGENGSPGAPGAPG 1047

Query: 544  HVCDP-PSGPDTTPAASDLPTEQPPSPQPGPPAASHTPEKQASSFDFNGPYLGPPHSRSL 602
            H   P P GP              P+  PGP  +   P  Q    D      G    R  
Sbjct: 1048 HPGPPGPVGPAGKSGDRGESGPAGPAGAPGPAGSRGAPGPQGPRGD-----KGETGERGA 1102

Query: 603  PDILGQPEPPQEGGSQKSPPPGSLEYLCLPAGGQVQLVPLAQAMGPGQAVEVERRPSQGA 662
              I G    P   G+  SP P                                    QGA
Sbjct: 1103 AGIKGHRGFPGNPGAPGSPGPAG---------------------------------QQGA 1129

Query: 663  AGSPSLESGGGPAPPALGPRVGGQDQKDSPVAIPMSSGDTEDPGVASGYVSSADLVFTPN 722
             GSP      GP  P+  P   G      P+  P   G+  + G                
Sbjct: 1130 IGSPGPAGPRGPVGPSGPPGKDGTSGHPGPIGPPGPRGNRGERGSEG------------- 1176

Query: 723  SGASSVSLVPSLGLPSDQTPSLCPGLASGPPGAPGPVKSG 762
                      S G P    P        GPPGAPGP   G
Sbjct: 1177 ----------SPGHPGQPGP-------PGPPGAPGPCCGG 1199



 Score = 37.4 bits (85), Expect = 0.063
 Identities = 105/426 (24%), Positives = 134/426 (31%), Gaps = 91/426 (21%)

Query: 496 PPGSMSAFTS-GSPPHQGPWGSRFPELEGVFPVGFGDSEVSPLTIEDPKHVCDPPSGPDT 554
           PPG+     S GSP +QGP G                 +  P     P     P SGP  
Sbjct: 184 PPGTSGHPGSPGSPGYQGPPGE--------------PGQAGPSGPPGPPGAIGP-SGPAG 228

Query: 555 TPAASDLPTEQPPSPQPGPPAASHTPE-------KQASSFDFNGPYLGPPHSRSLPDILG 607
               S  P        PGPP              K    FD      G       P + G
Sbjct: 229 KDGESGRPGRPGERGLPGPPGIKGPAGIPGFPGMKGHRGFDGRN---GEKGETGAPGLKG 285

Query: 608 QPEPPQEGGSQKSPPPGSLEYLCLPAGGQVQLVPLAQAMGPGQAVEVERRPSQGAAGSPS 667
           +   P E G+     PG +     P G         +   PG       R + GA GS  
Sbjct: 286 ENGLPGENGA-----PGPMG----PRGAP------GERGRPGLPGAAGARGNDGARGSDG 330

Query: 668 LESGGGPAPPALGPRVGGQDQKDSPVAIPMSS---GDTEDPGV-----ASGYVSSADLVF 719
                GP   A  P   G   +  P   P S+   G   +PG      A G      +  
Sbjct: 331 QPGPPGPPGTAGFPGSPGAKGEVGPAGSPGSNGAPGQRGEPGPQGHAGAQGPPGPPGING 390

Query: 720 TPNS----GASSVSLVPSL----GLPSDQTPSLCPGL--ASGPPGAPG----PVKSGFEG 765
           +P      G + +   P L    G P     +  PGL   +G PG  G    P   G  G
Sbjct: 391 SPGGKGEMGPAGIPGAPGLMGARGPPGPAGANGAPGLRGGAGEPGKNGAKGEPGPRGERG 450

Query: 766 YVELPPIEGR--------SPRSPRNNPVPPEA-----------KSPVLNPGERPADVSPT 806
              +P + G         SP  P  N +P  A             P   PGE+       
Sbjct: 451 EAGIPGVPGAKGEDGKDGSPGEPGANGLPGAAGERGAPGFRGPAGPNGIPGEKGPAGERG 510

Query: 807 SPQPEGLLVLQQVGDYCFLPGLGPGPLSLRSKPSSP-GPGPEIKNLDQAFQVKK----PP 861
           +P P G            +PG GPG   +R  P SP GPG + K      Q +     PP
Sbjct: 511 APGPAGPRGAAGEPGRDGVPG-GPG---MRGMPGSPGGPGSDGKPGPPGSQGESGRPGPP 566

Query: 862 GQAVPQ 867
           G + P+
Sbjct: 567 GPSGPR 572



 Score = 35.8 bits (81), Expect = 0.18
 Identities = 33/124 (26%), Positives = 48/124 (38%), Gaps = 26/124 (20%)

Query: 732 PSLGLPSDQTPSLCPGLASGPPGAPGPVKSGFEGYVELPPIEGRSPRSPRNNPVPPEAKS 791
           P+  +P  +  ++CP     PP AP              P  G+ P+ P+ +P PP    
Sbjct: 75  PNPEIPFGECCAVCPQ----PPTAP------------TRPPNGQGPQGPKGDPGPPGIPG 118

Query: 792 PVLNPGERPADVSPTSPQPEGLLVLQQVGDYCFLP---------GLGPGPLSLRSKPSSP 842
              +PG      SP SP P G+      G   + P         G+  G L+    P+ P
Sbjct: 119 RNGDPGIPGQPGSPGSPGPPGICESCPTGPQNYSPQYDSYDVKSGVAVGGLAGYPGPAGP 178

Query: 843 GPGP 846
            PGP
Sbjct: 179 -PGP 181


>gi|110832843 TBP-associated factor 4 [Homo sapiens]
          Length = 1085

 Score = 66.2 bits (160), Expect = 1e-10
 Identities = 92/382 (24%), Positives = 130/382 (34%), Gaps = 61/382 (15%)

Query: 498 GSMSAFTSGSPPHQGPWGSRFPELEGVFPVGFGDSEVSPLTIEDPKHVCDPPSGPDTTPA 557
           GS+ +  + S  H      R PE+        G+  VS            P       PA
Sbjct: 27  GSLESQLAASAAHHHHLAPRTPEVRAAAAGALGNHVVSG----------SPAGAAGAGPA 76

Query: 558 ASDLPTEQPPSPQPGPPAASHTPEKQASSFDFNGPYLGPPHSRSLPDILGQPEPPQEGGS 617
           A   P E  P   P PP A              GP    P S   P +   P PP    +
Sbjct: 77  A---PAEGAPGAAPEPPPAGRARPGGG------GPQRPGPPSPRRPLVPAGPAPP---AA 124

Query: 618 QKSPPPGSLEYLCLPAGGQVQLVPLAQAM--GPGQAVEVERRPSQGAAGSPSLESGGGPA 675
           +  PPP      C P       VP A A+  GP  A     +P+  AA +     G GP 
Sbjct: 125 KLRPPPEGSAGSCAP-------VPAAAAVAAGPEPAPAGPAKPAGPAALAARAGPGPGPG 177

Query: 676 P-PALGPRVGGQDQKDSPVAIPMSSGDTEDPGVASGYVSSADLVFTPNSGASSVSLVPSL 734
           P P  GP   G  +   P A    +G      + + + ++A  V   N+G +++  +P  
Sbjct: 178 PGPGPGP---GPGKPAGPGAAQTLNGSA---ALLNSHHAAAPAVSLVNNGPAALLPLPKP 231

Query: 735 GLPSD--QTPSLCPGLASGPPGAPGPVKSGFEGYVELPPIEGRSPRSPRNNPVPPEAKSP 792
             P    QTP      A   P AP P  +         P       +P   P PP A + 
Sbjct: 232 AAPGTVIQTPPFVGAAAPPAPAAPSPPAA---------PAPAAPAAAP---PPPPPAPAT 279

Query: 793 VLNPGERPADVSPTSPQPEGLLVLQQVGDYCFLPGLGP---GPLSLRSKP------SSPG 843
           +  P   PA     +P        Q  G     P   P   GP  +  +P      ++P 
Sbjct: 280 LARPPGHPAGPPTAAPAVPPPAAAQNGGSAGAAPAPAPAAGGPAGVSGQPGPGAAAAAPA 339

Query: 844 PGPEIKNLDQAFQVKKPPGQAV 865
           PG + ++  +  Q   P  Q +
Sbjct: 340 PGVKAESPKRVVQAAPPAAQTL 361



 Score = 48.5 bits (114), Expect = 3e-05
 Identities = 73/282 (25%), Positives = 105/282 (37%), Gaps = 29/282 (10%)

Query: 548 PPSGPDTTPAASDLPTEQPPSPQPGPPAASHTPEKQASSFDFNGPYLGPPHSRSLPDILG 607
           PP+    +P A+  P     +P P PPA +             G   GPP   +    + 
Sbjct: 249 PPAPAAPSPPAAPAPAAPAAAPPPPPPAPATLARPP-------GHPAGPP---TAAPAVP 298

Query: 608 QPEPPQEGGSQKSPPPGSLEYLCLPAGGQVQLVPLAQAMGPGQAVEVE--RRPSQGAAGS 665
            P   Q GGS     P        PAG   Q  P A A  P   V+ E  +R  Q A  +
Sbjct: 299 PPAAAQNGGS-AGAAPAPAPAAGGPAGVSGQPGPGAAAAAPAPGVKAESPKRVVQAAPPA 357

Query: 666 PSLESGGGPAPPA----LGPRVGGQDQKDSPVAIPMSSGDTEDPGVASGYVSSADLVFTP 721
               +  GPA  A    +GP + G     + V  P     T  P  A+G V+ + L  TP
Sbjct: 358 AQTLAASGPASTAASMVIGPTMQGALPSPAAVPPPAPGTPTGLPKGAAGAVTQS-LSRTP 416

Query: 722 NSGASSV--SLVPSLGLPSDQTPSLCPGLASGPPGAPGPVKSGFE-GYVELPPIEGRSPR 778
            +  S +  +L P++  P    P   P         PG V    E G + + P +  +  
Sbjct: 417 TATTSGIRATLTPTVLAPRLPQPPQNPTNIQNFQLPPGMVLVRSENGQLLMIPQQALAQM 476

Query: 779 SPRNNPVPPEAKSPVLNPGERPADVSPTSPQPEGLLVLQQVG 820
             + +  P    +P      RPA  +PTS  P  +  +Q  G
Sbjct: 477 QAQAHAQPQTTMAP------RPA--TPTSAPPVQISTVQAPG 510


>gi|19924099 synapsin I isoform Ia [Homo sapiens]
          Length = 705

 Score = 66.2 bits (160), Expect = 1e-10
 Identities = 78/277 (28%), Positives = 96/277 (34%), Gaps = 47/277 (16%)

Query: 549 PSGPDTTPAASDLPTEQPPSPQPGPPAASHTPEKQASSFDFNGP--------YLGPPHSR 600
           P G  T+   +  P +Q P PQ GPP     P++Q        P         LGPP   
Sbjct: 443 PLGRQTSQQPAGPPAQQRPPPQGGPPQPGPGPQRQGPPLQQRPPPQGQQHLSGLGPPAGS 502

Query: 601 SLPDILGQP-EPPQEGGSQKSPPPGSLEYLCLPAGGQVQLVPLAQAMGPGQAVEVERRPS 659
            LP  L  P   PQ+  SQ +PP           G   Q  P+A   G   A      PS
Sbjct: 503 PLPQRLPSPTSAPQQPASQAAPP---------TQGQGRQSRPVAGGPGAPPAARPPASPS 553

Query: 660 -QGAAGSPSL---ESGGGPAPP-ALGPRVGGQDQKDSPVAIPMSSGDTEDPGVASGYVSS 714
            Q  AG P      S  GPAPP A G   GGQ ++  P   P  +G              
Sbjct: 554 PQRQAGPPQATRQTSVSGPAPPKASGAPPGGQQRQGPPQKPPGPAG-------------- 599

Query: 715 ADLVFTPNSGASSVSLVPSLGLPSDQTPSLCPGLASGPPGAPGPVKSGFEGYVELPPIEG 774
                 P   AS    VP  G P+ Q P        GP G P P  +        PP   
Sbjct: 600 ------PTRQASQAGPVPRTGPPTTQQPR---PSGPGPAGRPKPQLAQKPSQDVPPPATA 650

Query: 775 RSPRSPRNNPVPPEAKSPVLNPGERPADVSPTSPQPE 811
            +   P       ++ +   N  E PA   P+  Q E
Sbjct: 651 AAGGPPHPQLNKSQSLTNAFNLPE-PAPPRPSLSQDE 686


>gi|89276751 alpha 1 type V collagen preproprotein [Homo sapiens]
          Length = 1838

 Score = 65.1 bits (157), Expect = 3e-10
 Identities = 95/367 (25%), Positives = 126/367 (34%), Gaps = 41/367 (11%)

Query: 547  DPPSGP--DTTPAASDLPTEQP-PSPQPGPPAAS----HTPEKQASSFDFNGPYLGPPHS 599
            D P+GP  +  P     PT  P P   PGPP       H  ++  + F       GPP  
Sbjct: 939  DGPAGPPGERGPNGPQGPTGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPPGV 998

Query: 600  RSLPDILGQPEPPQEGGSQKSPPPGSLEYLCLPAGGQVQLVPLAQAMGPGQAVEVERRPS 659
                   G+  P  E G    P P   + L   AG +        A  PG+      R  
Sbjct: 999  VGPQGPTGETGPMGERGHPGPPGPPGEQGLPGLAGKEGTKGDPGPAGLPGKDGPPGLRGF 1058

Query: 660  QGAAGSPSL---------ESGGGPAPPALGPRVGGQDQKDSPVAIPMSSGDTEDPGVASG 710
             G  G P           E   GP  PA  P   G      P+ IP   G    PG A  
Sbjct: 1059 PGDRGLPGPVGALGLKGNEGPPGPPGPAGSPGERGPAGAAGPIGIPGRPGPQGPPGPAGE 1118

Query: 711  YVSSADLVFTPNSGASSVSLVPSLGLPSDQTPSLCPGLASGPPGAPGPVKSGFEGYVELP 770
              +  +    P   A    L   +GLP            +GP G PG  + G +G +  P
Sbjct: 1119 KGAPGEK--GPQGPAGRDGLQGPVGLPG----------PAGPVGPPG--EDGDKGEIGEP 1164

Query: 771  PIEG-RSPRSPRNNPVPPEAKSPVLNPGERPADVSPTSPQPEGLLVLQQVGDYCFLPGLG 829
              +G +  +  +  P P   + P+  PG   AD  P     +GL   +        PG  
Sbjct: 1165 GQKGSKGDKGEQGPPGPTGPQGPIGQPGPSGADGEPGPRGQQGLFGQKGDEGPRGFPG-P 1223

Query: 830  PGPLSLRSKPSSPGPGPEIKNLDQAFQVKKPPGQAVPQVPVIQLFKALKQQDYLSLPPWE 889
            PGP+ L+  P  PG   E  ++ Q      PPG   P+ P           D    PP  
Sbjct: 1224 PGPVGLQGLPGPPGEKGETGDVGQ----MGPPGPPGPRGP-----SGAPGADGPQGPPGG 1274

Query: 890  VNKPGEV 896
            +  PG V
Sbjct: 1275 IGNPGAV 1281



 Score = 61.6 bits (148), Expect = 3e-09
 Identities = 108/402 (26%), Positives = 131/402 (32%), Gaps = 104/402 (25%)

Query: 496  PPGSMSAFTSGSPPHQGPWGSRFPELEGVFPVGFGDSEVSPLTIEDPKHVCDPPSG---- 551
            PPG   A   G+P  +GP G          P G  D    P+ +  P     PP      
Sbjct: 1112 PPGP--AGEKGAPGEKGPQG----------PAG-RDGLQGPVGLPGPAGPVGPPGEDGDK 1158

Query: 552  -----PDTTPAASDLPTEQPPSP--------QPGPPAASHTPEKQASSFDFN-----GP- 592
                 P    +  D   + PP P        QPGP  A   P  +     F      GP 
Sbjct: 1159 GEIGEPGQKGSKGDKGEQGPPGPTGPQGPIGQPGPSGADGEPGPRGQQGLFGQKGDEGPR 1218

Query: 593  -YLGPPHSRSLPDILGQPEPPQEGGS--QKSPP--PGSLEYLCLPAGGQVQLVPLAQAMG 647
             + GPP    L  + G P    E G   Q  PP  PG       P+G      P     G
Sbjct: 1219 GFPGPPGPVGLQGLPGPPGEKGETGDVGQMGPPGPPGPRG----PSGAPGADGPQGPPGG 1274

Query: 648  PGQAVEVERRPSQGAAGSPSLESGGGPAPP--------------ALGPR-----VGGQDQ 688
             G    V  +   G AG P L   GGP  P              A GP       G    
Sbjct: 1275 IGNPGAVGEKGEPGEAGEPGLPGEGGPPGPKGERGEKGESGPSGAAGPPGPKGPPGDDGP 1334

Query: 689  KDSP--VAIPMSSGDTEDPGVASGYVSSADLVFTPNSGASSVSLVPSLGLPSDQTPSLCP 746
            K SP  V  P   G   +PG A       D       G +      S G   +  PS  P
Sbjct: 1335 KGSPGPVGFPGDPGPPGEPGPAGQDGPPGDKGDDGEPGQTG-----SPGPTGEPGPSGPP 1389

Query: 747  GLASGPPGAPGPV-KSGFEGYVELPPIEGRSPRSPRNNPVPPEAKSPVLNPGERPADVSP 805
            G   GPPG  GP  + G +G      +EG           PP    P+   G      +P
Sbjct: 1390 G-KRGPPGPAGPEGRQGEKGAKGEAGLEG-----------PPGKTGPIGPQG------AP 1431

Query: 806  TSPQPEGLLVLQQVGDYCFLPGLGPGPLSLRSKPSSPGP-GP 846
              P P+GL  +             PGP+  +  P SPGP GP
Sbjct: 1432 GKPGPDGLRGI-------------PGPVGEQGLPGSPGPDGP 1460



 Score = 54.7 bits (130), Expect = 4e-07
 Identities = 94/374 (25%), Positives = 123/374 (32%), Gaps = 63/374 (16%)

Query: 540 EDPKHVCDPPSGPDTTPAASDLPTEQPPSPQPGPPA---ASHTPEKQASSFDFN--GPYL 594
           E+P    DP +G +   + +D      P+P PG  A        E+   + D N   PY 
Sbjct: 362 ENPDQPTDPGAGAEIPTSTADTSNSSNPAPPPGEGADDLEGEFTEETIRNLDENYYDPYY 421

Query: 595 GPPHSRS------------LPDILGQP--EPPQEG-------GSQKSPPPGSLEYLCLPA 633
            P  S S            + + +G P  E  Q+G       G     PPG      LP 
Sbjct: 422 DPTSSPSEIGPGMPANQDTIYEGIGGPRGEKGQKGEPAIIEPGMLIEGPPGPEGPAGLP- 480

Query: 634 GGQVQLVPLAQAMGPGQAVEVERRPSQGAAGSPS---------LESGGGPAPPALGPRVG 684
           G    + P  Q   PG+     R    GA G P             GGG    + GP V 
Sbjct: 481 GPPGTMGPTGQVGDPGERGPPGRPGLPGADGLPGPPGTMLMLPFRFGGGGDAGSKGPMVS 540

Query: 685 GQDQKDSPVAIPMSSGDTEDPGVASGYVSSADLVFTPNSGA-----SSVSLVPSLGLPSD 739
            Q+ +   + +  +      P    G       V  P SG        V      G+   
Sbjct: 541 AQESQAQAI-LQQARLALRGPAGPMGLTGRPGPVGPPGSGGLKGEPGDVGPQGPRGVQGP 599

Query: 740 QTPSLCPGL--------ASGPPGAPGPV-KSGFEGYVELPPIEG-RSPRSPRNNPVPPEA 789
             P+  PG         A G PG  GP    GF+G   LP  +G R    P   P PP  
Sbjct: 600 PGPAGKPGRRGRAGSDGARGMPGQTGPKGDRGFDGLAGLPGEKGHRGDPGPSGPPGPPGD 659

Query: 790 KSPVLNPGERPADVSPTSPQPEGLLVLQQVGDYCFLPGLGPGPLSLRSKPSSPGPGPEIK 849
                + GE      P  P P GLL  +        P   PGP  +      PGP   + 
Sbjct: 660 DGERGDDGEVGPRGLPGEPGPRGLLGPKG-------PPGPPGPPGVTGMDGQPGPKGNVG 712

Query: 850 NLDQAFQVKKPPGQ 863
              +      PPGQ
Sbjct: 713 PQGE----PGPPGQ 722



 Score = 49.3 bits (116), Expect = 2e-05
 Identities = 111/388 (28%), Positives = 131/388 (33%), Gaps = 58/388 (14%)

Query: 505  SGSPPHQGPWGSRFPELEGVFPVGFGDSEVSPLTIEDPKHVCDPPSGPDTT-------PA 557
            SG P   G  G R  + E V P G    E  P  +  PK    PP  P  T       P 
Sbjct: 651  SGPPGPPGDDGERGDDGE-VGPRGL-PGEPGPRGLLGPKGPPGPPGPPGVTGMDGQPGPK 708

Query: 558  ASDLPTEQPPSP-QPGPPAASHTPEKQASSFD--FNGPYLGPPHSRSLPDILGQPE---- 610
             +  P  +P  P Q G P A   P  Q +       GP LG P    +P   G P     
Sbjct: 709  GNVGPQGEPGPPGQQGNPGAQGLPGPQGAIGPPGEKGP-LGKPGLPGMPGADGPPGHPGK 767

Query: 611  --PPQEGGSQKSP-PPGSLEYLCLPAG--GQVQLVPLAQAMG-------PGQAVEVERRP 658
              PP E G Q  P P G + Y   P G  G   +  L    G       PG   ++  + 
Sbjct: 768  EGPPGEKGGQGPPGPQGPIGYPG-PRGVKGADGIRGLKGTKGEKGEDGFPGFKGDMGIKG 826

Query: 659  SQGAAGSPSLESGGGPAPPALGPRVGGQDQKDSPVAIPMSSGDTEDPGVASGYV------ 712
             +G  G P      GP  P      GG +    P+  P   G    PG+  GY       
Sbjct: 827  DRGEIGPPGPRGEDGPEGP---KGRGGPNGDPGPLGPPGEKGKLGVPGL-PGYPGRQGPK 882

Query: 713  -SSADLVFTPNSGASSVSLVPSLGLPSDQTPSLCPGLASGP---PGAPGPV-KSGFEGYV 767
             S     F   +G       P    P  Q     P    GP    G PGP   SG +G  
Sbjct: 883  GSIGFPGFPGANGEKGGRGTPGKPGPRGQRGPTGPRGERGPRGITGKPGPKGNSGGDGPA 942

Query: 768  ELPPIEGRSPRSPRNNPVPPEAKSPVLNPGERPADVSPTSPQPEGLLVLQQVGDYCFLPG 827
              PP E R P  P+     P  K P   PG    D  P  P   G    Q        PG
Sbjct: 943  G-PPGE-RGPNGPQGPTGFPGPKGP---PGPPGKDGLPGHPGQRGETGFQGKTGPPGPPG 997

Query: 828  -LGP-------GPLSLRSKPSSPGPGPE 847
             +GP       GP+  R  P  PGP  E
Sbjct: 998  VVGPQGPTGETGPMGERGHPGPPGPPGE 1025



 Score = 44.7 bits (104), Expect = 4e-04
 Identities = 78/311 (25%), Positives = 94/311 (30%), Gaps = 56/311 (18%)

Query: 506  GSPPHQGPWGSRFPELEGVFPVGFGDSEVSPLTIEDPKHVCDPPS--GPDTTPAASDLPT 563
            G PP  GP G R  +            E  P     P     PP   GP  +P     P 
Sbjct: 1299 GGPP--GPKGERGEK-----------GESGPSGAAGPPGPKGPPGDDGPKGSPGPVGFPG 1345

Query: 564  EQPPSPQPGPPAASHTPEKQASSFDFNGPYLGPPHSRSLPDILGQPEPPQEGGSQKSPPP 623
            +  P  +PGP      P  +           G P     P   G+P P    G +  P P
Sbjct: 1346 DPGPPGEPGPAGQDGPPGDKGDD--------GEPGQTGSPGPTGEPGPSGPPGKRGPPGP 1397

Query: 624  GSLEYLCLPAGGQVQLVPLAQAMGPGQAVEVERRPSQGAAGSPS---LESGGGPAPPALG 680
                    P G Q +     +A   G   +      QGA G P    L    GP      
Sbjct: 1398 AG------PEGRQGEKGAKGEAGLEGPPGKTGPIGPQGAPGKPGPDGLRGIPGPVGEQGL 1451

Query: 681  PRVGGQDQKDSPVAIPMSSGDTEDPGVAS--GYVSSADLVFTPNSGASSVSLVPSLGLPS 738
            P   G D    P+  P   G   D G     G+     L+  P             GLP 
Sbjct: 1452 PGSPGPDGPPGPMGPPGLPGLKGDSGPKGEKGHPGLIGLIGPPGEQGEK----GDRGLPG 1507

Query: 739  DQTPSLCPGLAS-----------GPPGAPGPVKSGFEGYVELPPIEGRSPRSPRNNPVPP 787
             Q  S   G              GPPG PGP   G +G        G  P+    +P PP
Sbjct: 1508 PQGSSGPKGEQGITGPSGPIGPPGPPGLPGP--PGPKGAKGSSGPTG--PKGEAGHPGPP 1563

Query: 788  EAKSPVLNPGE 798
                P   PGE
Sbjct: 1564 GPPGP---PGE 1571



 Score = 35.0 bits (79), Expect = 0.31
 Identities = 64/300 (21%), Positives = 102/300 (34%), Gaps = 67/300 (22%)

Query: 552 PDTTPAASDLPTEQPPSPQPGPPAASHTPEKQASSFDFNGPYLGPP-------------- 597
           PD   A  D P  Q P+P           + +  ++ +  PY   P              
Sbjct: 242 PDCDTAVPDTPQSQDPNPDEYYTEG----DGEGETYYYEYPYYEDPEDLGKEPTPSKKPV 297

Query: 598 ----HSRSLPDIL------GQPEPPQEGGSQKSPPPGSLEYLCLPAGGQVQLVPLAQAMG 647
                +  +P+ L        P P    G+ K    G  +Y  +P+       P    + 
Sbjct: 298 EAAKETTEVPEELTPTPTEAAPMPETSEGAGKEEDVGIGDYDYVPSEDYYTPSPY-DDLT 356

Query: 648 PGQAVEVERRPSQGAAG------SPSLESGGGPAPPALGPRVGGQDQKDSPVAIPMSSGD 701
            G+  E   +P+   AG      +    +   PAPP   P  G  D +          G+
Sbjct: 357 YGEGEENPDQPTDPGAGAEIPTSTADTSNSSNPAPP---PGEGADDLE----------GE 403

Query: 702 TEDPGVASGYVSSADLVFTPNSGASSVSLVPSLGLPSDQTPSLCPGLA-----SGPPGAP 756
             +  + +   +  D  + P S  S +      G+P++Q  ++  G+       G  G P
Sbjct: 404 FTEETIRNLDENYYDPYYDPTSSPSEI----GPGMPANQ-DTIYEGIGGPRGEKGQKGEP 458

Query: 757 GPVKSGFEGYVELPPIEGRSPRSPRNNPVPPEAKSP---VLNPGERPADVSPTSPQPEGL 813
             ++ G    +E PP     P  P   P PP    P   V +PGER     P  P  +GL
Sbjct: 459 AIIEPGM--LIEGPP----GPEGPAGLPGPPGTMGPTGQVGDPGERGPPGRPGLPGADGL 512


>gi|116284398 WAS/WASL interacting protein family, member 1 [Homo
           sapiens]
          Length = 503

 Score = 65.1 bits (157), Expect = 3e-10
 Identities = 98/398 (24%), Positives = 129/398 (32%), Gaps = 75/398 (18%)

Query: 481 PSKSHLFQNGSAELWPPGSMSAFTSGSPPHQGPWGSRF--------PELEGVFPVGFGDS 532
           P    LFQ G  +L    +    + GS P   P G R         P   G FPV     
Sbjct: 98  PGLGGLFQAGMPKLRSTANRDNDSGGSRPPLLPPGGRSTSAKPFSPPSGPGRFPVPSPGH 157

Query: 533 EVSPLTIEDPKHVCDPPSGPDTTPAASDLPTEQPPSPQPGPPAASHTPEKQASSFDFNGP 592
              P    +P+    PP  PD       +P   P +P+                     P
Sbjct: 158 RSGP---PEPQRNRMPPPRPDVGSKPDSIPPPVPSTPR---------------------P 193

Query: 593 YLGPPHSRSLPDILGQPEPPQEGGSQKSPPPGSLEYLCLPAGGQVQLVPLAQAMGPGQAV 652
               PH+R  P + G P  P  G    +PPP          GG ++  PL+ +       
Sbjct: 194 IQSSPHNRGSPPVPGGPRQPSPG---PTPPPFPGNRGTALGGGSIRQSPLSSSS------ 244

Query: 653 EVERRPSQGAAGSPSLESGGGPAPPALGPRVGGQDQKDSPVAIPMSSGDTEDPGVASGYV 712
               RP      S +L+    P PP +G R     +     A+P        P V S   
Sbjct: 245 PFSNRPPLPPTPSRALDDKPPPPPPPVGNRPSIHRE-----AVPPPPPQNNKPPVPSTPR 299

Query: 713 SSADLVFTPNSGASSVSLVPSLGLPS---DQTPSLCP---GLASGPPGAPGPVKSGFEGY 766
            SA     P     S    P L   S   D+TP L      L+S  P  P P +SG    
Sbjct: 300 PSASSQAPPPPPPPSRPGPPPLPPSSSGNDETPRLPQRNLSLSSSTPPLPSPGRSG---- 355

Query: 767 VELPPIEGRSPRSP------RNNPVPPEAKSPVLNPGERPADVSPTSPQPEGLLVLQQVG 820
             LPP     P  P      R+ P+PP           R    +P  P   G+       
Sbjct: 356 -PLPPPPSERPPPPVRDPPGRSGPLPPPPPVSRNGSTSRALPATPQLPSRSGV------- 407

Query: 821 DYCFLPGLGPGPLSLRSKPS--SPGPGPEIKNLDQAFQ 856
                P  GP P     +PS  +P P P   ++   FQ
Sbjct: 408 ---DSPRSGPRPPLPPDRPSAGAPPPPPPSTSIRNGFQ 442



 Score = 39.3 bits (90), Expect = 0.017
 Identities = 54/216 (25%), Positives = 70/216 (32%), Gaps = 49/216 (22%)

Query: 496 PPGSMSAFTSGSPPHQGPWGSRFPELEGVFPVGFGDSEVSPLTIEDPKHVCDPPSGPDTT 555
           PP    A     PP   P G+R                +    +  P    + P  P T 
Sbjct: 253 PPTPSRALDDKPPPPPPPVGNR--------------PSIHREAVPPPPPQNNKPPVPSTP 298

Query: 556 --PAASDLPTEQPPSPQPGPP----------AASHTPEKQAS---------SFDFNGPYL 594
              A+S  P   PP  +PGPP               P++  S         S   +GP  
Sbjct: 299 RPSASSQAPPPPPPPSRPGPPPLPPSSSGNDETPRLPQRNLSLSSSTPPLPSPGRSGPLP 358

Query: 595 GPPHSRSLPDILGQPEPPQEGGSQKSPPPGSLE---YLCLPAGGQVQLVPLAQAMGPGQA 651
            PP  R  P +    +PP   G    PPP S        LPA    QL   +    P   
Sbjct: 359 PPPSERPPPPV---RDPPGRSGPLPPPPPVSRNGSTSRALPA--TPQLPSRSGVDSPRSG 413

Query: 652 VEVERRPSQGAAGSPSLESGGGPAPPALGPRVGGQD 687
                 P + +AG+P       P PP+   R G QD
Sbjct: 414 PRPPLPPDRPSAGAPP------PPPPSTSIRNGFQD 443


>gi|38373695 WAS/WASL interacting protein family, member 1 [Homo
           sapiens]
          Length = 503

 Score = 65.1 bits (157), Expect = 3e-10
 Identities = 98/398 (24%), Positives = 129/398 (32%), Gaps = 75/398 (18%)

Query: 481 PSKSHLFQNGSAELWPPGSMSAFTSGSPPHQGPWGSRF--------PELEGVFPVGFGDS 532
           P    LFQ G  +L    +    + GS P   P G R         P   G FPV     
Sbjct: 98  PGLGGLFQAGMPKLRSTANRDNDSGGSRPPLLPPGGRSTSAKPFSPPSGPGRFPVPSPGH 157

Query: 533 EVSPLTIEDPKHVCDPPSGPDTTPAASDLPTEQPPSPQPGPPAASHTPEKQASSFDFNGP 592
              P    +P+    PP  PD       +P   P +P+                     P
Sbjct: 158 RSGP---PEPQRNRMPPPRPDVGSKPDSIPPPVPSTPR---------------------P 193

Query: 593 YLGPPHSRSLPDILGQPEPPQEGGSQKSPPPGSLEYLCLPAGGQVQLVPLAQAMGPGQAV 652
               PH+R  P + G P  P  G    +PPP          GG ++  PL+ +       
Sbjct: 194 IQSSPHNRGSPPVPGGPRQPSPG---PTPPPFPGNRGTALGGGSIRQSPLSSSS------ 244

Query: 653 EVERRPSQGAAGSPSLESGGGPAPPALGPRVGGQDQKDSPVAIPMSSGDTEDPGVASGYV 712
               RP      S +L+    P PP +G R     +     A+P        P V S   
Sbjct: 245 PFSNRPPLPPTPSRALDDKPPPPPPPVGNRPSIHRE-----AVPPPPPQNNKPPVPSTPR 299

Query: 713 SSADLVFTPNSGASSVSLVPSLGLPS---DQTPSLCP---GLASGPPGAPGPVKSGFEGY 766
            SA     P     S    P L   S   D+TP L      L+S  P  P P +SG    
Sbjct: 300 PSASSQAPPPPPPPSRPGPPPLPPSSSGNDETPRLPQRNLSLSSSTPPLPSPGRSG---- 355

Query: 767 VELPPIEGRSPRSP------RNNPVPPEAKSPVLNPGERPADVSPTSPQPEGLLVLQQVG 820
             LPP     P  P      R+ P+PP           R    +P  P   G+       
Sbjct: 356 -PLPPPPSERPPPPVRDPPGRSGPLPPPPPVSRNGSTSRALPATPQLPSRSGV------- 407

Query: 821 DYCFLPGLGPGPLSLRSKPS--SPGPGPEIKNLDQAFQ 856
                P  GP P     +PS  +P P P   ++   FQ
Sbjct: 408 ---DSPRSGPRPPLPPDRPSAGAPPPPPPSTSIRNGFQ 442



 Score = 39.3 bits (90), Expect = 0.017
 Identities = 54/216 (25%), Positives = 70/216 (32%), Gaps = 49/216 (22%)

Query: 496 PPGSMSAFTSGSPPHQGPWGSRFPELEGVFPVGFGDSEVSPLTIEDPKHVCDPPSGPDTT 555
           PP    A     PP   P G+R                +    +  P    + P  P T 
Sbjct: 253 PPTPSRALDDKPPPPPPPVGNR--------------PSIHREAVPPPPPQNNKPPVPSTP 298

Query: 556 --PAASDLPTEQPPSPQPGPP----------AASHTPEKQAS---------SFDFNGPYL 594
              A+S  P   PP  +PGPP               P++  S         S   +GP  
Sbjct: 299 RPSASSQAPPPPPPPSRPGPPPLPPSSSGNDETPRLPQRNLSLSSSTPPLPSPGRSGPLP 358

Query: 595 GPPHSRSLPDILGQPEPPQEGGSQKSPPPGSLE---YLCLPAGGQVQLVPLAQAMGPGQA 651
            PP  R  P +    +PP   G    PPP S        LPA    QL   +    P   
Sbjct: 359 PPPSERPPPPV---RDPPGRSGPLPPPPPVSRNGSTSRALPA--TPQLPSRSGVDSPRSG 413

Query: 652 VEVERRPSQGAAGSPSLESGGGPAPPALGPRVGGQD 687
                 P + +AG+P       P PP+   R G QD
Sbjct: 414 PRPPLPPDRPSAGAPP------PPPPSTSIRNGFQD 443


>gi|209571537 proline-rich protein BstNI subfamily 2 [Homo sapiens]
          Length = 416

 Score = 64.3 bits (155), Expect = 5e-10
 Identities = 96/357 (26%), Positives = 117/357 (32%), Gaps = 41/357 (11%)

Query: 542 PKHVCDPPSGPDTTPAASDLPTEQPP----SPQPGPPAASHTPEKQASSFDFNGPYLGPP 597
           P+    PP  P   P       + PP     PQ  PP   + P+         GP     
Sbjct: 47  PQGPPSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGD 106

Query: 598 HSRSLPDILGQPE-PPQEGGSQKS---PPPGSLEYLCLPAGGQVQ-LVPLAQAMGPGQAV 652
            SRS     G+P+ PP +GG+Q     PPPG  +      G + Q   P  +  GP    
Sbjct: 107 KSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQG 166

Query: 653 EVERRPSQGAAGSPSLESGGGPAPPALGPRVGGQDQKDSPVAIPMSSGDTED----PGVA 708
           + + R S+   G P      GP P       G       P   P   G+       PG  
Sbjct: 167 DNKSRSSRSPPGKPQ-----GPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKP 221

Query: 709 SGYVSSAD-LVFTPNSGASSVSLVPSLGLPSDQTPSLCPGLASGPP--GAPGPVKSGFEG 765
            G     D    +  S        P  G    Q P   PG   GPP  G   P      G
Sbjct: 222 QGPPPQGDNKSQSARSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPG 281

Query: 766 YVELPPIEG----RSPRSPRNNPVPPEAKSPVLNPGERPADVSPTSPQPEGLLVLQQVGD 821
             + PP +G    RS RSP   P  P  +      G  P    P  P P+G    Q    
Sbjct: 282 KPQGPPPQGGSKSRSSRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPP 341

Query: 822 YCFLPGLGPGP--------LSLRSKPSSP-GPGPEIKNLDQAFQVKKPPGQAVPQVP 869
               PG   GP         S RS P  P GP  +  N  Q      PP    PQ P
Sbjct: 342 ----PGKPQGPPPQGGSKSRSARSPPGKPQGPPQQEGNNPQG---PPPPAGGNPQQP 391


>gi|98985810 alpha 1 type XI collagen isoform B preproprotein [Homo
            sapiens]
          Length = 1818

 Score = 63.2 bits (152), Expect = 1e-09
 Identities = 98/376 (26%), Positives = 135/376 (35%), Gaps = 58/376 (15%)

Query: 504  TSGSPPHQGPWGSRFPE-LEGVFPVGFGDSEVSPLTIEDPKHVCDPPSGPDTTPAASDLP 562
            TSG     GP G R P+  +G  PVGF            PK    PP G D  P      
Sbjct: 917  TSGGDGPPGPPGERGPQGPQG--PVGF----------PGPKGPPGPP-GKDGLPGHPGQR 963

Query: 563  TEQPPSPQPGPPAASHTPEKQASSFDFNGPY--------LGPPHSRSLPDILGQPEPPQE 614
             E     + GPP        Q  + +  GP          GPP  + LP   G+      
Sbjct: 964  GETGFQGKTGPPGPGGVVGPQGPTGE-TGPIGERGHPGPPGPPGEQGLPGAAGKE----- 1017

Query: 615  GGSQKSPPPGSLEYLCLPAGGQVQLVPLAQAMGPGQAVEVERRPSQGAAGSPSLESGGGP 674
             G++  P P  +     PAG  ++  P  + + PG         +QGA G    E   GP
Sbjct: 1018 -GAKGDPGPQGISGKDGPAG--LRGFPGERGL-PG---------AQGAPGLKGGEGPQGP 1064

Query: 675  APPALGPRVGGQDQKDSPVAIPMSSGDTEDPGVASGYVSSADLVFTPNSGASSVSLVPSL 734
              P   P   G      P+ +P   G    PG A    +  +    P   A    +   +
Sbjct: 1065 PGPVGSPGERGSAGTAGPIGLPGRPGPQGPPGPAGEKGAPGEK--GPQGPAGRDGVQGPV 1122

Query: 735  GLPSDQTPSLCPGLASGPPGAPGPVKSGFEGYVELPPIEG-RSPRSPRNNPVPPEAKSPV 793
            GLP            +GP G+PG  + G +G +  P  +G +  +     P PP  + PV
Sbjct: 1123 GLPG----------PAGPAGSPG--EDGDKGEIGEPGQKGSKGDKGENGPPGPPGLQGPV 1170

Query: 794  LNPGERPADVSPTSPQPEGLLVLQQVGDYCFLPGLGPGPLSLRSKPSSPGPGPEIKNLDQ 853
              PG    D  P     +G+   +        PG  PGP+ L+  P  PG   E  ++  
Sbjct: 1171 GAPGIAGGDGEPGPRGQQGMFGQKGDEGARGFPG-PPGPIGLQGLPGPPGEKGENGDVG- 1228

Query: 854  AFQVKKPPGQAVPQVP 869
                  PPG   PQ P
Sbjct: 1229 PMGPPGPPGPRGPQGP 1244



 Score = 50.8 bits (120), Expect = 6e-06
 Identities = 88/333 (26%), Positives = 112/333 (33%), Gaps = 43/333 (12%)

Query: 496  PPGSMSAFTS-GSPPHQGPWGSRFPELEGVFPVGFGD----SEVSPLTIEDPKHVCDPPS 550
            PPGS+ +    G     G  G+  P  E       G+     E  P     P     PP 
Sbjct: 1253 PPGSVGSVGGVGEKGEPGEAGNPGPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPG 1312

Query: 551  --GPDTTPAASDLPTEQPPSPQPGPPAASHTPEKQASSFDFNGPYLGPPHSRSLPDILGQ 608
              GP   P     P +  P  +PGP         +    D   P  GPP         G 
Sbjct: 1313 DDGPKGNPGPVGFPGDPGPPGEPGPAGQDGVGGDKGEDGDPGQP--GPPGPSGEA---GP 1367

Query: 609  PEPPQEGGSQKSPPPGSLEYLCLPAGGQVQLVPLAQAMGPGQAVEVERRPSQGAAGSPSL 668
            P PP + G     PPG+        G Q +     +A   G   +      QG AG P  
Sbjct: 1368 PGPPGKRG-----PPGAAG----AEGRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKPGP 1418

Query: 669  ESGGGPAPPALG----PRVGGQDQKDSPVAIPMSSGDTEDPGV--ASGYVSSADLVFTPN 722
            E   G  P  +G    P   GQD    P+  P   G   DPG     G+     L+  P 
Sbjct: 1419 EGLRG-IPGPVGEQGLPGAAGQDGPPGPMGPPGLPGLKGDPGSKGEKGHPGLIGLIGPPG 1477

Query: 723  SGASSVSLVPSLGLPSDQTPSLCPGLASGPPGAPGPVKSGFEGYVELPPIEGRSPRSPRN 782
                        GLP  Q     PG A G  G PGP  +G  G    P + G  P+ P+ 
Sbjct: 1478 EQGEK----GDRGLPGTQG---SPG-AKGDGGIPGP--AGPLGPPGPPGLPG--PQGPKG 1525

Query: 783  NPVPPEAKSPVLNPGERPADVSPTSPQPEGLLV 815
            N     +  P    G+      P SP P G ++
Sbjct: 1526 N---KGSTGPAGQKGDSGLPGPPGSPGPPGEVI 1555



 Score = 47.4 bits (111), Expect = 6e-05
 Identities = 87/347 (25%), Positives = 111/347 (31%), Gaps = 80/347 (23%)

Query: 539 IEDPKHVCDPPSGPDTTPAASDLPTEQPPSPQPGPPAASHTPEKQASSFDFNGPYLGPPH 598
           + +P  + + P GP         P  Q P+  PG P                    GPP 
Sbjct: 445 VVEPGMLVEGPPGPAGPAGIMGPPGLQGPTGPPGDPGDR-----------------GPPG 487

Query: 599 SRSLPDILGQPEPPQEGGSQKSPPPGSLEYLCLPAGGQVQLVPLAQAMGPGQAVEVERRP 658
              LP   G P            PPG++  L    GG             G  +  +   
Sbjct: 488 RPGLPGADGLP-----------GPPGTMLMLPFRYGGD---------GSKGPTISAQEAQ 527

Query: 659 SQGAAGSPSLESGGGPAPPALGPRVGGQDQKDSPVAIPMSS---GDTEDPGVASGYVSSA 715
           +Q       +   G P P  L  R G       PV  P SS   G++ DPG         
Sbjct: 528 AQAILQQARIALRGPPGPMGLTGRPG-------PVGGPGSSGAKGESGDPG--------- 571

Query: 716 DLVFTPNSGASSVSLVPS-LGLPSDQTPSLCPGLASGPPGAPGPV-KSGFEGYVELPPIE 773
                   G   V   P   G P  +      G   G PG PG     GF+G   LP  +
Sbjct: 572 ------PQGPRGVQGPPGPTGKPGKRGRPGADG-GRGMPGEPGAKGDRGFDGLPGLPGDK 624

Query: 774 G-RSPRSPRNNPVPPEAKSPVLNPGERPADVSPTSPQPEGLLVLQQVGDYCFLPGLG--- 829
           G R  R P+  P PP         GE      P    P GLL  +        PG+    
Sbjct: 625 GHRGERGPQGPPGPPGDDGMRGEDGEIGPRGLPGEAGPRGLLGPRGTPGAPGQPGMAGVD 684

Query: 830 --PGP---LSLRSKPSSPG----PGPEIKNLDQAFQVKKPPGQAVPQ 867
             PGP   +  + +P  PG    PGP+   L        PPG+  PQ
Sbjct: 685 GPPGPKGNMGPQGEPGPPGQQGNPGPQ--GLPGPQGPIGPPGEKGPQ 729



 Score = 42.7 bits (99), Expect = 0.001
 Identities = 82/326 (25%), Positives = 106/326 (32%), Gaps = 46/326 (14%)

Query: 547  DPPSGPDTTPAASDLPTEQPP-------SPQPGPPAASHTPEKQASSFDFNGPYLGPPHS 599
            D P+G    P    LP  Q          PQ GPP    +P ++ S+        GP   
Sbjct: 1032 DGPAGLRGFPGERGLPGAQGAPGLKGGEGPQ-GPPGPVGSPGERGSAGT-----AGPIGL 1085

Query: 600  RSLPDILGQPEPPQEGGS--QKSPP-PGSLEYLCLPAGGQVQLVPLAQAMGPGQAVEVER 656
               P   G P P  E G+  +K P  P   + +  P G      P       G   E+  
Sbjct: 1086 PGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGVQGPVGLPGPAGPAGSPGEDGDKGEIGE 1145

Query: 657  RPSQGAAGSPSLESGGGPAPPAL-----GPRVGGQDQKDSPVAIPMSSGDTEDPGVAS-- 709
               +G+ G       G P PP L      P + G D +  P       G   D G     
Sbjct: 1146 PGQKGSKGDKG--ENGPPGPPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQKGDEGARGFP 1203

Query: 710  ---GYVSSADLVFTPNSGASSVSLVPSLGLPSDQTPS--LCPGLASGPPGAPGPVKSGFE 764
               G +    L   P     +  + P +G P    P     P  A GP G PG V S   
Sbjct: 1204 GPPGPIGLQGLPGPPGEKGENGDVGP-MGPPGPPGPRGPQGPNGADGPQGPPGSVGS--- 1259

Query: 765  GYVELPPIEGRSPRSPRNNPVPP---EAKSPVLNPGERPADVSPTSPQPEGLLVLQQVGD 821
                +  +  +       NP PP       P    GE+     P +  P G       GD
Sbjct: 1260 ----VGGVGEKGEPGEAGNPGPPGEAGVGGPKGERGEKGEAGPPGAAGPPG--AKGPPGD 1313

Query: 822  YCFLPGLGPGPLSLRSKPSSPG-PGP 846
                P   PGP+     P  PG PGP
Sbjct: 1314 DG--PKGNPGPVGFPGDPGPPGEPGP 1337



 Score = 41.2 bits (95), Expect = 0.004
 Identities = 81/296 (27%), Positives = 101/296 (34%), Gaps = 42/296 (14%)

Query: 595  GPPHSRSLPDILGQPEPPQEGGSQKSPPPGSLEYLCLP-AGGQVQLVPLAQAMGP-GQAV 652
            GP         LG P  P   G Q   P GS  +   P A G+     +A   GP GQ  
Sbjct: 838  GPSGQAGEKGKLGVPGLPGYPGRQG--PKGSTGFPGFPGANGEKGARGVAGKPGPRGQRG 895

Query: 653  EVERRPSQGA---AGSPSLE-SGGGPAPPALGPRVGGQDQKDSPVAIPMSSGDTEDP--- 705
                R S+GA    G P  + + GG  PP   P   G      PV  P   G    P   
Sbjct: 896  PTGPRGSRGARGPTGKPGPKGTSGGDGPPG-PPGERGPQGPQGPVGFPGPKGPPGPPGKD 954

Query: 706  GVASGYVSSADLVFTPNSGASSVSLVPSLGLPSDQTPSLCPGLASGPPGAPG----PVKS 761
            G+        +  F   +G      V     P+ +T  +      GPPG PG    P  +
Sbjct: 955  GLPGHPGQRGETGFQGKTGPPGPGGVVGPQGPTGETGPIGERGHPGPPGPPGEQGLPGAA 1014

Query: 762  GFEGYVELPPIEGRSPRS--------PRNNPVPPEAKSPVLNPGERPADVSPTSPQPEGL 813
            G EG    P  +G S +         P    +P    +P L  GE P       P P G 
Sbjct: 1015 GKEGAKGDPGPQGISGKDGPAGLRGFPGERGLPGAQGAPGLKGGEGPQG----PPGPVG- 1069

Query: 814  LVLQQVGDYCFLPGLGPGPLSLRSKPSSPGPGPEIKNLDQAFQVKKPPGQAVPQVP 869
                  G+       GP  L  R  P  P PGP  +        K  PG+  PQ P
Sbjct: 1070 ----SPGERGSAGTAGPIGLPGRPGPQGP-PGPAGE--------KGAPGEKGPQGP 1112



 Score = 38.5 bits (88), Expect = 0.028
 Identities = 59/233 (25%), Positives = 82/233 (35%), Gaps = 29/233 (12%)

Query: 548 PPSGPDTTPAASDL--PTEQPPSPQPGPPAASHTPEKQASSFDFNGPYL-GPPHSRS--- 601
           P  GP ++ A  +   P  Q P    GPP  +  P K+       G  + G P ++    
Sbjct: 554 PVGGPGSSGAKGESGDPGPQGPRGVQGPPGPTGKPGKRGRPGADGGRGMPGEPGAKGDRG 613

Query: 602 ---LPDILGQPEPPQEGGSQKSPPPGSLEYLCLPAGGQVQLVPLAQAMGPGQAVEVERRP 658
              LP + G      E G Q  P P   + +    G   ++ P       G    +  R 
Sbjct: 614 FDGLPGLPGDKGHRGERGPQGPPGPPGDDGM---RGEDGEIGPRGLPGEAGPRGLLGPRG 670

Query: 659 SQGAAGSPSLESGGGPAPPA--LGPR----VGGQDQKDSPVAIPMSSGDTEDPGVASGYV 712
           + GA G P +    GP  P   +GP+      GQ     P  +P   G    PG   G  
Sbjct: 671 TPGAPGQPGMAGVDGPPGPKGNMGPQGEPGPPGQQGNPGPQGLPGPQGPIGPPG-EKGPQ 729

Query: 713 SSADLVFTPNSGASSVSLVPSLGLPSDQTPSLCPGLASGPPGAPGPVKSGFEG 765
               L   P +           G P  +  S   G A GPPG  GP+  G+ G
Sbjct: 730 GKPGLAGLPGADGPP-------GHPGKEGQSGEKG-ALGPPGPQGPI--GYPG 772



 Score = 31.6 bits (70), Expect = 3.5
 Identities = 93/390 (23%), Positives = 121/390 (31%), Gaps = 87/390 (22%)

Query: 540 EDPKHVCDPPSGPDTTPAASDLPTEQPPSPQPGPPAASHTPEKQASSFDFNGPYLGPPHS 599
           + P+ V  PP GP   P     P        PG P A     K    FD      G    
Sbjct: 573 QGPRGVQGPP-GPTGKPGKRGRPGADGGRGMPGEPGA-----KGDRGFDGLPGLPGDKGH 626

Query: 600 RSLPDILGQPEPPQEGGSQ-------------KSPPPGSLEYLCLP-AGGQVQLVPLAQA 645
           R      G P PP + G +             ++ P G L     P A GQ  +  +   
Sbjct: 627 RGERGPQGPPGPPGDDGMRGEDGEIGPRGLPGEAGPRGLLGPRGTPGAPGQPGMAGVDGP 686

Query: 646 MGPGQAVEVERRPSQ-GAAGSPSLESGGGPAPPALGPRVGGQDQKDSPVAIPMSSGDTED 704
            GP   +  +  P   G  G+P  +   GP  P   P   G   K     +P + G    
Sbjct: 687 PGPKGNMGPQGEPGPPGQQGNPGPQGLPGPQGPIGPPGEKGPQGKPGLAGLPGADGPPGH 746

Query: 705 PGVAS-----------------GY-----VSSADLV--FTPNSGASSVSLVP----SLGL 736
           PG                    GY     V  AD V     + G       P     +GL
Sbjct: 747 PGKEGQSGEKGALGPPGPQGPIGYPGPRGVKGADGVRGLKGSKGEKGEDGFPGFKGDMGL 806

Query: 737 -----------PSDQTPSLCPGLASGPPGAPGPV-KSGFEGYVELPPIEG----RSPRSP 780
                      P  +     P   +GP G PGP  ++G +G + +P + G    + P+  
Sbjct: 807 KGDRGEVGQIGPRGEDGPEGPKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQGPKGS 866

Query: 781 RNNPVPPEAKSPVLNPGERPADVSPTSPQPEGLLVLQQVGDYCFLPGLGP-GPLSLRSKP 839
              P  P A       GE+ A      P P G     Q G        GP G    R   
Sbjct: 867 TGFPGFPGAN------GEKGARGVAGKPGPRG-----QRGP------TGPRGSRGARGPT 909

Query: 840 SSPGPGPEIKNLDQAFQVKKPPGQAVPQVP 869
             PGP    K          PPG+  PQ P
Sbjct: 910 GKPGP----KGTSGGDGPPGPPGERGPQGP 935


>gi|98985808 alpha 1 type XI collagen isoform C preproprotein [Homo
            sapiens]
          Length = 1767

 Score = 63.2 bits (152), Expect = 1e-09
 Identities = 98/376 (26%), Positives = 135/376 (35%), Gaps = 58/376 (15%)

Query: 504  TSGSPPHQGPWGSRFPE-LEGVFPVGFGDSEVSPLTIEDPKHVCDPPSGPDTTPAASDLP 562
            TSG     GP G R P+  +G  PVGF            PK    PP G D  P      
Sbjct: 866  TSGGDGPPGPPGERGPQGPQG--PVGF----------PGPKGPPGPP-GKDGLPGHPGQR 912

Query: 563  TEQPPSPQPGPPAASHTPEKQASSFDFNGPY--------LGPPHSRSLPDILGQPEPPQE 614
             E     + GPP        Q  + +  GP          GPP  + LP   G+      
Sbjct: 913  GETGFQGKTGPPGPGGVVGPQGPTGE-TGPIGERGHPGPPGPPGEQGLPGAAGKE----- 966

Query: 615  GGSQKSPPPGSLEYLCLPAGGQVQLVPLAQAMGPGQAVEVERRPSQGAAGSPSLESGGGP 674
             G++  P P  +     PAG  ++  P  + + PG         +QGA G    E   GP
Sbjct: 967  -GAKGDPGPQGISGKDGPAG--LRGFPGERGL-PG---------AQGAPGLKGGEGPQGP 1013

Query: 675  APPALGPRVGGQDQKDSPVAIPMSSGDTEDPGVASGYVSSADLVFTPNSGASSVSLVPSL 734
              P   P   G      P+ +P   G    PG A    +  +    P   A    +   +
Sbjct: 1014 PGPVGSPGERGSAGTAGPIGLPGRPGPQGPPGPAGEKGAPGEK--GPQGPAGRDGVQGPV 1071

Query: 735  GLPSDQTPSLCPGLASGPPGAPGPVKSGFEGYVELPPIEG-RSPRSPRNNPVPPEAKSPV 793
            GLP            +GP G+PG  + G +G +  P  +G +  +     P PP  + PV
Sbjct: 1072 GLPG----------PAGPAGSPG--EDGDKGEIGEPGQKGSKGDKGENGPPGPPGLQGPV 1119

Query: 794  LNPGERPADVSPTSPQPEGLLVLQQVGDYCFLPGLGPGPLSLRSKPSSPGPGPEIKNLDQ 853
              PG    D  P     +G+   +        PG  PGP+ L+  P  PG   E  ++  
Sbjct: 1120 GAPGIAGGDGEPGPRGQQGMFGQKGDEGARGFPG-PPGPIGLQGLPGPPGEKGENGDVG- 1177

Query: 854  AFQVKKPPGQAVPQVP 869
                  PPG   PQ P
Sbjct: 1178 PMGPPGPPGPRGPQGP 1193



 Score = 50.8 bits (120), Expect = 6e-06
 Identities = 88/333 (26%), Positives = 112/333 (33%), Gaps = 43/333 (12%)

Query: 496  PPGSMSAFTS-GSPPHQGPWGSRFPELEGVFPVGFGD----SEVSPLTIEDPKHVCDPPS 550
            PPGS+ +    G     G  G+  P  E       G+     E  P     P     PP 
Sbjct: 1202 PPGSVGSVGGVGEKGEPGEAGNPGPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPG 1261

Query: 551  --GPDTTPAASDLPTEQPPSPQPGPPAASHTPEKQASSFDFNGPYLGPPHSRSLPDILGQ 608
              GP   P     P +  P  +PGP         +    D   P  GPP         G 
Sbjct: 1262 DDGPKGNPGPVGFPGDPGPPGEPGPAGQDGVGGDKGEDGDPGQP--GPPGPSGEA---GP 1316

Query: 609  PEPPQEGGSQKSPPPGSLEYLCLPAGGQVQLVPLAQAMGPGQAVEVERRPSQGAAGSPSL 668
            P PP + G     PPG+        G Q +     +A   G   +      QG AG P  
Sbjct: 1317 PGPPGKRG-----PPGAAG----AEGRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKPGP 1367

Query: 669  ESGGGPAPPALG----PRVGGQDQKDSPVAIPMSSGDTEDPGV--ASGYVSSADLVFTPN 722
            E   G  P  +G    P   GQD    P+  P   G   DPG     G+     L+  P 
Sbjct: 1368 EGLRG-IPGPVGEQGLPGAAGQDGPPGPMGPPGLPGLKGDPGSKGEKGHPGLIGLIGPPG 1426

Query: 723  SGASSVSLVPSLGLPSDQTPSLCPGLASGPPGAPGPVKSGFEGYVELPPIEGRSPRSPRN 782
                        GLP  Q     PG A G  G PGP  +G  G    P + G  P+ P+ 
Sbjct: 1427 EQGEK----GDRGLPGTQG---SPG-AKGDGGIPGP--AGPLGPPGPPGLPG--PQGPKG 1474

Query: 783  NPVPPEAKSPVLNPGERPADVSPTSPQPEGLLV 815
            N     +  P    G+      P SP P G ++
Sbjct: 1475 N---KGSTGPAGQKGDSGLPGPPGSPGPPGEVI 1504



 Score = 47.4 bits (111), Expect = 6e-05
 Identities = 87/347 (25%), Positives = 111/347 (31%), Gaps = 80/347 (23%)

Query: 539 IEDPKHVCDPPSGPDTTPAASDLPTEQPPSPQPGPPAASHTPEKQASSFDFNGPYLGPPH 598
           + +P  + + P GP         P  Q P+  PG P                    GPP 
Sbjct: 394 VVEPGMLVEGPPGPAGPAGIMGPPGLQGPTGPPGDPGDR-----------------GPPG 436

Query: 599 SRSLPDILGQPEPPQEGGSQKSPPPGSLEYLCLPAGGQVQLVPLAQAMGPGQAVEVERRP 658
              LP   G P            PPG++  L    GG             G  +  +   
Sbjct: 437 RPGLPGADGLP-----------GPPGTMLMLPFRYGGD---------GSKGPTISAQEAQ 476

Query: 659 SQGAAGSPSLESGGGPAPPALGPRVGGQDQKDSPVAIPMSS---GDTEDPGVASGYVSSA 715
           +Q       +   G P P  L  R G       PV  P SS   G++ DPG         
Sbjct: 477 AQAILQQARIALRGPPGPMGLTGRPG-------PVGGPGSSGAKGESGDPG--------- 520

Query: 716 DLVFTPNSGASSVSLVPS-LGLPSDQTPSLCPGLASGPPGAPGPV-KSGFEGYVELPPIE 773
                   G   V   P   G P  +      G   G PG PG     GF+G   LP  +
Sbjct: 521 ------PQGPRGVQGPPGPTGKPGKRGRPGADG-GRGMPGEPGAKGDRGFDGLPGLPGDK 573

Query: 774 G-RSPRSPRNNPVPPEAKSPVLNPGERPADVSPTSPQPEGLLVLQQVGDYCFLPGLG--- 829
           G R  R P+  P PP         GE      P    P GLL  +        PG+    
Sbjct: 574 GHRGERGPQGPPGPPGDDGMRGEDGEIGPRGLPGEAGPRGLLGPRGTPGAPGQPGMAGVD 633

Query: 830 --PGP---LSLRSKPSSPG----PGPEIKNLDQAFQVKKPPGQAVPQ 867
             PGP   +  + +P  PG    PGP+   L        PPG+  PQ
Sbjct: 634 GPPGPKGNMGPQGEPGPPGQQGNPGPQ--GLPGPQGPIGPPGEKGPQ 678



 Score = 42.7 bits (99), Expect = 0.001
 Identities = 82/326 (25%), Positives = 106/326 (32%), Gaps = 46/326 (14%)

Query: 547  DPPSGPDTTPAASDLPTEQPP-------SPQPGPPAASHTPEKQASSFDFNGPYLGPPHS 599
            D P+G    P    LP  Q          PQ GPP    +P ++ S+        GP   
Sbjct: 981  DGPAGLRGFPGERGLPGAQGAPGLKGGEGPQ-GPPGPVGSPGERGSAGT-----AGPIGL 1034

Query: 600  RSLPDILGQPEPPQEGGS--QKSPP-PGSLEYLCLPAGGQVQLVPLAQAMGPGQAVEVER 656
               P   G P P  E G+  +K P  P   + +  P G      P       G   E+  
Sbjct: 1035 PGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGVQGPVGLPGPAGPAGSPGEDGDKGEIGE 1094

Query: 657  RPSQGAAGSPSLESGGGPAPPAL-----GPRVGGQDQKDSPVAIPMSSGDTEDPGVAS-- 709
               +G+ G       G P PP L      P + G D +  P       G   D G     
Sbjct: 1095 PGQKGSKGDKG--ENGPPGPPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQKGDEGARGFP 1152

Query: 710  ---GYVSSADLVFTPNSGASSVSLVPSLGLPSDQTPS--LCPGLASGPPGAPGPVKSGFE 764
               G +    L   P     +  + P +G P    P     P  A GP G PG V S   
Sbjct: 1153 GPPGPIGLQGLPGPPGEKGENGDVGP-MGPPGPPGPRGPQGPNGADGPQGPPGSVGS--- 1208

Query: 765  GYVELPPIEGRSPRSPRNNPVPP---EAKSPVLNPGERPADVSPTSPQPEGLLVLQQVGD 821
                +  +  +       NP PP       P    GE+     P +  P G       GD
Sbjct: 1209 ----VGGVGEKGEPGEAGNPGPPGEAGVGGPKGERGEKGEAGPPGAAGPPG--AKGPPGD 1262

Query: 822  YCFLPGLGPGPLSLRSKPSSPG-PGP 846
                P   PGP+     P  PG PGP
Sbjct: 1263 DG--PKGNPGPVGFPGDPGPPGEPGP 1286



 Score = 41.2 bits (95), Expect = 0.004
 Identities = 81/296 (27%), Positives = 101/296 (34%), Gaps = 42/296 (14%)

Query: 595  GPPHSRSLPDILGQPEPPQEGGSQKSPPPGSLEYLCLP-AGGQVQLVPLAQAMGP-GQAV 652
            GP         LG P  P   G Q   P GS  +   P A G+     +A   GP GQ  
Sbjct: 787  GPSGQAGEKGKLGVPGLPGYPGRQG--PKGSTGFPGFPGANGEKGARGVAGKPGPRGQRG 844

Query: 653  EVERRPSQGA---AGSPSLE-SGGGPAPPALGPRVGGQDQKDSPVAIPMSSGDTEDP--- 705
                R S+GA    G P  + + GG  PP   P   G      PV  P   G    P   
Sbjct: 845  PTGPRGSRGARGPTGKPGPKGTSGGDGPPG-PPGERGPQGPQGPVGFPGPKGPPGPPGKD 903

Query: 706  GVASGYVSSADLVFTPNSGASSVSLVPSLGLPSDQTPSLCPGLASGPPGAPG----PVKS 761
            G+        +  F   +G      V     P+ +T  +      GPPG PG    P  +
Sbjct: 904  GLPGHPGQRGETGFQGKTGPPGPGGVVGPQGPTGETGPIGERGHPGPPGPPGEQGLPGAA 963

Query: 762  GFEGYVELPPIEGRSPRS--------PRNNPVPPEAKSPVLNPGERPADVSPTSPQPEGL 813
            G EG    P  +G S +         P    +P    +P L  GE P       P P G 
Sbjct: 964  GKEGAKGDPGPQGISGKDGPAGLRGFPGERGLPGAQGAPGLKGGEGPQG----PPGPVG- 1018

Query: 814  LVLQQVGDYCFLPGLGPGPLSLRSKPSSPGPGPEIKNLDQAFQVKKPPGQAVPQVP 869
                  G+       GP  L  R  P  P PGP  +        K  PG+  PQ P
Sbjct: 1019 ----SPGERGSAGTAGPIGLPGRPGPQGP-PGPAGE--------KGAPGEKGPQGP 1061



 Score = 38.5 bits (88), Expect = 0.028
 Identities = 59/233 (25%), Positives = 82/233 (35%), Gaps = 29/233 (12%)

Query: 548 PPSGPDTTPAASDL--PTEQPPSPQPGPPAASHTPEKQASSFDFNGPYL-GPPHSRS--- 601
           P  GP ++ A  +   P  Q P    GPP  +  P K+       G  + G P ++    
Sbjct: 503 PVGGPGSSGAKGESGDPGPQGPRGVQGPPGPTGKPGKRGRPGADGGRGMPGEPGAKGDRG 562

Query: 602 ---LPDILGQPEPPQEGGSQKSPPPGSLEYLCLPAGGQVQLVPLAQAMGPGQAVEVERRP 658
              LP + G      E G Q  P P   + +    G   ++ P       G    +  R 
Sbjct: 563 FDGLPGLPGDKGHRGERGPQGPPGPPGDDGM---RGEDGEIGPRGLPGEAGPRGLLGPRG 619

Query: 659 SQGAAGSPSLESGGGPAPPA--LGPR----VGGQDQKDSPVAIPMSSGDTEDPGVASGYV 712
           + GA G P +    GP  P   +GP+      GQ     P  +P   G    PG   G  
Sbjct: 620 TPGAPGQPGMAGVDGPPGPKGNMGPQGEPGPPGQQGNPGPQGLPGPQGPIGPPG-EKGPQ 678

Query: 713 SSADLVFTPNSGASSVSLVPSLGLPSDQTPSLCPGLASGPPGAPGPVKSGFEG 765
               L   P +           G P  +  S   G A GPPG  GP+  G+ G
Sbjct: 679 GKPGLAGLPGADGPP-------GHPGKEGQSGEKG-ALGPPGPQGPI--GYPG 721



 Score = 31.6 bits (70), Expect = 3.5
 Identities = 93/390 (23%), Positives = 121/390 (31%), Gaps = 87/390 (22%)

Query: 540 EDPKHVCDPPSGPDTTPAASDLPTEQPPSPQPGPPAASHTPEKQASSFDFNGPYLGPPHS 599
           + P+ V  PP GP   P     P        PG P A     K    FD      G    
Sbjct: 522 QGPRGVQGPP-GPTGKPGKRGRPGADGGRGMPGEPGA-----KGDRGFDGLPGLPGDKGH 575

Query: 600 RSLPDILGQPEPPQEGGSQ-------------KSPPPGSLEYLCLP-AGGQVQLVPLAQA 645
           R      G P PP + G +             ++ P G L     P A GQ  +  +   
Sbjct: 576 RGERGPQGPPGPPGDDGMRGEDGEIGPRGLPGEAGPRGLLGPRGTPGAPGQPGMAGVDGP 635

Query: 646 MGPGQAVEVERRPSQ-GAAGSPSLESGGGPAPPALGPRVGGQDQKDSPVAIPMSSGDTED 704
            GP   +  +  P   G  G+P  +   GP  P   P   G   K     +P + G    
Sbjct: 636 PGPKGNMGPQGEPGPPGQQGNPGPQGLPGPQGPIGPPGEKGPQGKPGLAGLPGADGPPGH 695

Query: 705 PGVAS-----------------GY-----VSSADLV--FTPNSGASSVSLVP----SLGL 736
           PG                    GY     V  AD V     + G       P     +GL
Sbjct: 696 PGKEGQSGEKGALGPPGPQGPIGYPGPRGVKGADGVRGLKGSKGEKGEDGFPGFKGDMGL 755

Query: 737 -----------PSDQTPSLCPGLASGPPGAPGPV-KSGFEGYVELPPIEG----RSPRSP 780
                      P  +     P   +GP G PGP  ++G +G + +P + G    + P+  
Sbjct: 756 KGDRGEVGQIGPRGEDGPEGPKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQGPKGS 815

Query: 781 RNNPVPPEAKSPVLNPGERPADVSPTSPQPEGLLVLQQVGDYCFLPGLGP-GPLSLRSKP 839
              P  P A       GE+ A      P P G     Q G        GP G    R   
Sbjct: 816 TGFPGFPGAN------GEKGARGVAGKPGPRG-----QRGP------TGPRGSRGARGPT 858

Query: 840 SSPGPGPEIKNLDQAFQVKKPPGQAVPQVP 869
             PGP    K          PPG+  PQ P
Sbjct: 859 GKPGP----KGTSGGDGPPGPPGERGPQGP 884


>gi|98985806 alpha 1 type XI collagen isoform A preproprotein [Homo
            sapiens]
          Length = 1806

 Score = 63.2 bits (152), Expect = 1e-09
 Identities = 98/376 (26%), Positives = 135/376 (35%), Gaps = 58/376 (15%)

Query: 504  TSGSPPHQGPWGSRFPE-LEGVFPVGFGDSEVSPLTIEDPKHVCDPPSGPDTTPAASDLP 562
            TSG     GP G R P+  +G  PVGF            PK    PP G D  P      
Sbjct: 905  TSGGDGPPGPPGERGPQGPQG--PVGF----------PGPKGPPGPP-GKDGLPGHPGQR 951

Query: 563  TEQPPSPQPGPPAASHTPEKQASSFDFNGPY--------LGPPHSRSLPDILGQPEPPQE 614
             E     + GPP        Q  + +  GP          GPP  + LP   G+      
Sbjct: 952  GETGFQGKTGPPGPGGVVGPQGPTGE-TGPIGERGHPGPPGPPGEQGLPGAAGKE----- 1005

Query: 615  GGSQKSPPPGSLEYLCLPAGGQVQLVPLAQAMGPGQAVEVERRPSQGAAGSPSLESGGGP 674
             G++  P P  +     PAG  ++  P  + + PG         +QGA G    E   GP
Sbjct: 1006 -GAKGDPGPQGISGKDGPAG--LRGFPGERGL-PG---------AQGAPGLKGGEGPQGP 1052

Query: 675  APPALGPRVGGQDQKDSPVAIPMSSGDTEDPGVASGYVSSADLVFTPNSGASSVSLVPSL 734
              P   P   G      P+ +P   G    PG A    +  +    P   A    +   +
Sbjct: 1053 PGPVGSPGERGSAGTAGPIGLPGRPGPQGPPGPAGEKGAPGEK--GPQGPAGRDGVQGPV 1110

Query: 735  GLPSDQTPSLCPGLASGPPGAPGPVKSGFEGYVELPPIEG-RSPRSPRNNPVPPEAKSPV 793
            GLP            +GP G+PG  + G +G +  P  +G +  +     P PP  + PV
Sbjct: 1111 GLPG----------PAGPAGSPG--EDGDKGEIGEPGQKGSKGDKGENGPPGPPGLQGPV 1158

Query: 794  LNPGERPADVSPTSPQPEGLLVLQQVGDYCFLPGLGPGPLSLRSKPSSPGPGPEIKNLDQ 853
              PG    D  P     +G+   +        PG  PGP+ L+  P  PG   E  ++  
Sbjct: 1159 GAPGIAGGDGEPGPRGQQGMFGQKGDEGARGFPG-PPGPIGLQGLPGPPGEKGENGDVG- 1216

Query: 854  AFQVKKPPGQAVPQVP 869
                  PPG   PQ P
Sbjct: 1217 PMGPPGPPGPRGPQGP 1232



 Score = 50.8 bits (120), Expect = 6e-06
 Identities = 88/333 (26%), Positives = 112/333 (33%), Gaps = 43/333 (12%)

Query: 496  PPGSMSAFTS-GSPPHQGPWGSRFPELEGVFPVGFGD----SEVSPLTIEDPKHVCDPPS 550
            PPGS+ +    G     G  G+  P  E       G+     E  P     P     PP 
Sbjct: 1241 PPGSVGSVGGVGEKGEPGEAGNPGPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPG 1300

Query: 551  --GPDTTPAASDLPTEQPPSPQPGPPAASHTPEKQASSFDFNGPYLGPPHSRSLPDILGQ 608
              GP   P     P +  P  +PGP         +    D   P  GPP         G 
Sbjct: 1301 DDGPKGNPGPVGFPGDPGPPGEPGPAGQDGVGGDKGEDGDPGQP--GPPGPSGEA---GP 1355

Query: 609  PEPPQEGGSQKSPPPGSLEYLCLPAGGQVQLVPLAQAMGPGQAVEVERRPSQGAAGSPSL 668
            P PP + G     PPG+        G Q +     +A   G   +      QG AG P  
Sbjct: 1356 PGPPGKRG-----PPGAAG----AEGRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKPGP 1406

Query: 669  ESGGGPAPPALG----PRVGGQDQKDSPVAIPMSSGDTEDPGV--ASGYVSSADLVFTPN 722
            E   G  P  +G    P   GQD    P+  P   G   DPG     G+     L+  P 
Sbjct: 1407 EGLRG-IPGPVGEQGLPGAAGQDGPPGPMGPPGLPGLKGDPGSKGEKGHPGLIGLIGPPG 1465

Query: 723  SGASSVSLVPSLGLPSDQTPSLCPGLASGPPGAPGPVKSGFEGYVELPPIEGRSPRSPRN 782
                        GLP  Q     PG A G  G PGP  +G  G    P + G  P+ P+ 
Sbjct: 1466 EQGEK----GDRGLPGTQG---SPG-AKGDGGIPGP--AGPLGPPGPPGLPG--PQGPKG 1513

Query: 783  NPVPPEAKSPVLNPGERPADVSPTSPQPEGLLV 815
            N     +  P    G+      P SP P G ++
Sbjct: 1514 N---KGSTGPAGQKGDSGLPGPPGSPGPPGEVI 1543



 Score = 47.4 bits (111), Expect = 6e-05
 Identities = 87/347 (25%), Positives = 111/347 (31%), Gaps = 80/347 (23%)

Query: 539 IEDPKHVCDPPSGPDTTPAASDLPTEQPPSPQPGPPAASHTPEKQASSFDFNGPYLGPPH 598
           + +P  + + P GP         P  Q P+  PG P                    GPP 
Sbjct: 433 VVEPGMLVEGPPGPAGPAGIMGPPGLQGPTGPPGDPGDR-----------------GPPG 475

Query: 599 SRSLPDILGQPEPPQEGGSQKSPPPGSLEYLCLPAGGQVQLVPLAQAMGPGQAVEVERRP 658
              LP   G P            PPG++  L    GG             G  +  +   
Sbjct: 476 RPGLPGADGLP-----------GPPGTMLMLPFRYGGD---------GSKGPTISAQEAQ 515

Query: 659 SQGAAGSPSLESGGGPAPPALGPRVGGQDQKDSPVAIPMSS---GDTEDPGVASGYVSSA 715
           +Q       +   G P P  L  R G       PV  P SS   G++ DPG         
Sbjct: 516 AQAILQQARIALRGPPGPMGLTGRPG-------PVGGPGSSGAKGESGDPG--------- 559

Query: 716 DLVFTPNSGASSVSLVPS-LGLPSDQTPSLCPGLASGPPGAPGPV-KSGFEGYVELPPIE 773
                   G   V   P   G P  +      G   G PG PG     GF+G   LP  +
Sbjct: 560 ------PQGPRGVQGPPGPTGKPGKRGRPGADG-GRGMPGEPGAKGDRGFDGLPGLPGDK 612

Query: 774 G-RSPRSPRNNPVPPEAKSPVLNPGERPADVSPTSPQPEGLLVLQQVGDYCFLPGLG--- 829
           G R  R P+  P PP         GE      P    P GLL  +        PG+    
Sbjct: 613 GHRGERGPQGPPGPPGDDGMRGEDGEIGPRGLPGEAGPRGLLGPRGTPGAPGQPGMAGVD 672

Query: 830 --PGP---LSLRSKPSSPG----PGPEIKNLDQAFQVKKPPGQAVPQ 867
             PGP   +  + +P  PG    PGP+   L        PPG+  PQ
Sbjct: 673 GPPGPKGNMGPQGEPGPPGQQGNPGPQ--GLPGPQGPIGPPGEKGPQ 717



 Score = 42.7 bits (99), Expect = 0.001
 Identities = 82/326 (25%), Positives = 106/326 (32%), Gaps = 46/326 (14%)

Query: 547  DPPSGPDTTPAASDLPTEQPP-------SPQPGPPAASHTPEKQASSFDFNGPYLGPPHS 599
            D P+G    P    LP  Q          PQ GPP    +P ++ S+        GP   
Sbjct: 1020 DGPAGLRGFPGERGLPGAQGAPGLKGGEGPQ-GPPGPVGSPGERGSAGT-----AGPIGL 1073

Query: 600  RSLPDILGQPEPPQEGGS--QKSPP-PGSLEYLCLPAGGQVQLVPLAQAMGPGQAVEVER 656
               P   G P P  E G+  +K P  P   + +  P G      P       G   E+  
Sbjct: 1074 PGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGVQGPVGLPGPAGPAGSPGEDGDKGEIGE 1133

Query: 657  RPSQGAAGSPSLESGGGPAPPAL-----GPRVGGQDQKDSPVAIPMSSGDTEDPGVAS-- 709
               +G+ G       G P PP L      P + G D +  P       G   D G     
Sbjct: 1134 PGQKGSKGDKG--ENGPPGPPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQKGDEGARGFP 1191

Query: 710  ---GYVSSADLVFTPNSGASSVSLVPSLGLPSDQTPS--LCPGLASGPPGAPGPVKSGFE 764
               G +    L   P     +  + P +G P    P     P  A GP G PG V S   
Sbjct: 1192 GPPGPIGLQGLPGPPGEKGENGDVGP-MGPPGPPGPRGPQGPNGADGPQGPPGSVGS--- 1247

Query: 765  GYVELPPIEGRSPRSPRNNPVPP---EAKSPVLNPGERPADVSPTSPQPEGLLVLQQVGD 821
                +  +  +       NP PP       P    GE+     P +  P G       GD
Sbjct: 1248 ----VGGVGEKGEPGEAGNPGPPGEAGVGGPKGERGEKGEAGPPGAAGPPG--AKGPPGD 1301

Query: 822  YCFLPGLGPGPLSLRSKPSSPG-PGP 846
                P   PGP+     P  PG PGP
Sbjct: 1302 DG--PKGNPGPVGFPGDPGPPGEPGP 1325



 Score = 41.2 bits (95), Expect = 0.004
 Identities = 81/296 (27%), Positives = 101/296 (34%), Gaps = 42/296 (14%)

Query: 595  GPPHSRSLPDILGQPEPPQEGGSQKSPPPGSLEYLCLP-AGGQVQLVPLAQAMGP-GQAV 652
            GP         LG P  P   G Q   P GS  +   P A G+     +A   GP GQ  
Sbjct: 826  GPSGQAGEKGKLGVPGLPGYPGRQG--PKGSTGFPGFPGANGEKGARGVAGKPGPRGQRG 883

Query: 653  EVERRPSQGA---AGSPSLE-SGGGPAPPALGPRVGGQDQKDSPVAIPMSSGDTEDP--- 705
                R S+GA    G P  + + GG  PP   P   G      PV  P   G    P   
Sbjct: 884  PTGPRGSRGARGPTGKPGPKGTSGGDGPPG-PPGERGPQGPQGPVGFPGPKGPPGPPGKD 942

Query: 706  GVASGYVSSADLVFTPNSGASSVSLVPSLGLPSDQTPSLCPGLASGPPGAPG----PVKS 761
            G+        +  F   +G      V     P+ +T  +      GPPG PG    P  +
Sbjct: 943  GLPGHPGQRGETGFQGKTGPPGPGGVVGPQGPTGETGPIGERGHPGPPGPPGEQGLPGAA 1002

Query: 762  GFEGYVELPPIEGRSPRS--------PRNNPVPPEAKSPVLNPGERPADVSPTSPQPEGL 813
            G EG    P  +G S +         P    +P    +P L  GE P       P P G 
Sbjct: 1003 GKEGAKGDPGPQGISGKDGPAGLRGFPGERGLPGAQGAPGLKGGEGPQG----PPGPVG- 1057

Query: 814  LVLQQVGDYCFLPGLGPGPLSLRSKPSSPGPGPEIKNLDQAFQVKKPPGQAVPQVP 869
                  G+       GP  L  R  P  P PGP  +        K  PG+  PQ P
Sbjct: 1058 ----SPGERGSAGTAGPIGLPGRPGPQGP-PGPAGE--------KGAPGEKGPQGP 1100



 Score = 38.5 bits (88), Expect = 0.028
 Identities = 59/233 (25%), Positives = 82/233 (35%), Gaps = 29/233 (12%)

Query: 548 PPSGPDTTPAASDL--PTEQPPSPQPGPPAASHTPEKQASSFDFNGPYL-GPPHSRS--- 601
           P  GP ++ A  +   P  Q P    GPP  +  P K+       G  + G P ++    
Sbjct: 542 PVGGPGSSGAKGESGDPGPQGPRGVQGPPGPTGKPGKRGRPGADGGRGMPGEPGAKGDRG 601

Query: 602 ---LPDILGQPEPPQEGGSQKSPPPGSLEYLCLPAGGQVQLVPLAQAMGPGQAVEVERRP 658
              LP + G      E G Q  P P   + +    G   ++ P       G    +  R 
Sbjct: 602 FDGLPGLPGDKGHRGERGPQGPPGPPGDDGM---RGEDGEIGPRGLPGEAGPRGLLGPRG 658

Query: 659 SQGAAGSPSLESGGGPAPPA--LGPR----VGGQDQKDSPVAIPMSSGDTEDPGVASGYV 712
           + GA G P +    GP  P   +GP+      GQ     P  +P   G    PG   G  
Sbjct: 659 TPGAPGQPGMAGVDGPPGPKGNMGPQGEPGPPGQQGNPGPQGLPGPQGPIGPPG-EKGPQ 717

Query: 713 SSADLVFTPNSGASSVSLVPSLGLPSDQTPSLCPGLASGPPGAPGPVKSGFEG 765
               L   P +           G P  +  S   G A GPPG  GP+  G+ G
Sbjct: 718 GKPGLAGLPGADGPP-------GHPGKEGQSGEKG-ALGPPGPQGPI--GYPG 760



 Score = 31.6 bits (70), Expect = 3.5
 Identities = 93/390 (23%), Positives = 121/390 (31%), Gaps = 87/390 (22%)

Query: 540 EDPKHVCDPPSGPDTTPAASDLPTEQPPSPQPGPPAASHTPEKQASSFDFNGPYLGPPHS 599
           + P+ V  PP GP   P     P        PG P A     K    FD      G    
Sbjct: 561 QGPRGVQGPP-GPTGKPGKRGRPGADGGRGMPGEPGA-----KGDRGFDGLPGLPGDKGH 614

Query: 600 RSLPDILGQPEPPQEGGSQ-------------KSPPPGSLEYLCLP-AGGQVQLVPLAQA 645
           R      G P PP + G +             ++ P G L     P A GQ  +  +   
Sbjct: 615 RGERGPQGPPGPPGDDGMRGEDGEIGPRGLPGEAGPRGLLGPRGTPGAPGQPGMAGVDGP 674

Query: 646 MGPGQAVEVERRPSQ-GAAGSPSLESGGGPAPPALGPRVGGQDQKDSPVAIPMSSGDTED 704
            GP   +  +  P   G  G+P  +   GP  P   P   G   K     +P + G    
Sbjct: 675 PGPKGNMGPQGEPGPPGQQGNPGPQGLPGPQGPIGPPGEKGPQGKPGLAGLPGADGPPGH 734

Query: 705 PGVAS-----------------GY-----VSSADLV--FTPNSGASSVSLVP----SLGL 736
           PG                    GY     V  AD V     + G       P     +GL
Sbjct: 735 PGKEGQSGEKGALGPPGPQGPIGYPGPRGVKGADGVRGLKGSKGEKGEDGFPGFKGDMGL 794

Query: 737 -----------PSDQTPSLCPGLASGPPGAPGPV-KSGFEGYVELPPIEG----RSPRSP 780
                      P  +     P   +GP G PGP  ++G +G + +P + G    + P+  
Sbjct: 795 KGDRGEVGQIGPRGEDGPEGPKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQGPKGS 854

Query: 781 RNNPVPPEAKSPVLNPGERPADVSPTSPQPEGLLVLQQVGDYCFLPGLGP-GPLSLRSKP 839
              P  P A       GE+ A      P P G     Q G        GP G    R   
Sbjct: 855 TGFPGFPGAN------GEKGARGVAGKPGPRG-----QRGP------TGPRGSRGARGPT 897

Query: 840 SSPGPGPEIKNLDQAFQVKKPPGQAVPQVP 869
             PGP    K          PPG+  PQ P
Sbjct: 898 GKPGP----KGTSGGDGPPGPPGERGPQGP 923


>gi|15890086 type IV collagen alpha 5 isoform 2 precursor [Homo
            sapiens]
          Length = 1691

 Score = 63.2 bits (152), Expect = 1e-09
 Identities = 116/399 (29%), Positives = 143/399 (35%), Gaps = 56/399 (14%)

Query: 478  IPNPSKSHLFQNGS-AELWPPGSMSAFTSGSPPHQG-PWGSRFPELEGVFPVGFGDSEVS 535
            +P P K  +  NG    + PPG       G P   G P     P L G+ P   GD    
Sbjct: 794  LPGP-KGDVGPNGQPGPMGPPGLPGIGVQGPPGPPGIPGPIGQPGLHGI-PGEKGDPGPP 851

Query: 536  PLTIEDPKHVCDPPSGPDTTPAASDLPTEQPPSPQ-PGPPAASHTPEKQASSFDFNGPY- 593
             L +  P      P  P         P   P SP  PG   AS  P  +        P  
Sbjct: 852  GLDVPGPPGERGSPGIPGAPG-----PIGPPGSPGLPGKAGASGFPGTKGEMGMMGPPGP 906

Query: 594  ---LGPPHSRSLPDILGQ---------PEPPQEGGSQKSP----PPGSLEYLCLPAGGQV 637
               LG P    +P + G          P P  E GS+  P    PPG ++   L + G+ 
Sbjct: 907  PGPLGIPGRSGVPGLKGDDGLQGQPGLPGPTGEKGSKGEPGLPGPPGPMDPNLLGSKGEK 966

Query: 638  Q---LVPLAQAMGPGQAVEVERRPSQ-GAAGSPSLESGGGPAPPALGPRVGGQDQKDSPV 693
                L  +    GP     +   P Q G +G P L    GP  P   P + GQ     P 
Sbjct: 967  GEPGLPGIPGVSGPKGYQGLPGDPGQPGLSGQPGLP---GPPGPKGNPGLPGQPGLIGPP 1023

Query: 694  AIPMSSGDTEDPGVASGYVSSADLVFTPNSGASSVSLVP-SLGLPSDQTPSLCPGLAS-G 751
             +  + GD   PG           V  P  G S V   P S GLP  +     PG++S G
Sbjct: 1024 GLKGTIGDMGFPGPQG--------VEGP-PGPSGVPGQPGSPGLPGQKGDKGDPGISSIG 1074

Query: 752  PPGAPGPV-KSGFEGYVELPPIEGR--SPRSPRNNPVPPEAKSPVLNPGERPADVSPTSP 808
             PG PGP  + G  GY   P I+G    P  P   P  P AK     PG       P +P
Sbjct: 1075 LPGLPGPKGEPGLPGYPGNPGIKGSVGDPGLP-GLPGTPGAKGQPGLPG------FPGTP 1127

Query: 809  QPEGLLVLQQVGDYCFLPGLGPGPLSLRSKPSSPGPGPE 847
             P G   +        LPG  PGP+     P  PGP  E
Sbjct: 1128 GPPGPKGISGPPGNPGLPG-EPGPVGGGGHPGQPGPPGE 1165



 Score = 53.5 bits (127), Expect = 8e-07
 Identities = 126/488 (25%), Positives = 148/488 (30%), Gaps = 125/488 (25%)

Query: 490 GSAELWPPGSMS-AFTSGSPPHQGPWGSRFPELEGVF----------PVGFGDSEVSPLT 538
           G+A + PPG        G    +GP G   P   G+           P G     + P  
Sbjct: 389 GAAVMGPPGPPGFPGERGQKGDEGPPGISIPGPPGLDGQPGAPGLPGPPGPAGPHIPP-- 446

Query: 539 IEDPKHVCDP-PSGPDTTPAASDLPTEQP-------------------PSPQPGPPAASH 578
                 +C+P P GP  +P    L  EQ                    P  QPG P    
Sbjct: 447 ---SDEICEPGPPGPPGSPGDKGLQGEQGVKGDKGDTCFNCIGTGISGPPGQPGLPGLPG 503

Query: 579 TPEKQASSFDFNGP-----YLGPPHSRSLPDILGQPEPPQEGGSQKSP------------ 621
            P     S  F G        G    + LP I G P  P   GS+  P            
Sbjct: 504 PP----GSLGFPGQKGEKGQAGATGPKGLPGIPGAPGAPGFPGSKGEPGDILTFPGMKGD 559

Query: 622 -----PPGSLEYLCLPAG-GQVQLVPLAQAMG-PGQAVEVERRPSQGAAGSPSLESGGGP 674
                 PG+     LP   GQ  L  L    G PG       R   G  G P L    GP
Sbjct: 560 KGELGSPGAPGLPGLPGTPGQDGLPGLPGPKGEPGGITFKGERGPPGNPGLPGLPGNIGP 619

Query: 675 -APPALGP-----RVGGQDQKDSPVAIPMSSGDTEDPGVASGYVSSADLVFTPNS----- 723
             PP  GP       G Q    +P   P   G   DPG          L   P       
Sbjct: 620 MGPPGFGPPGPVGEKGIQGVAGNP-GQPGIPGPKGDPGQTITQPGKPGLPGNPGRDGDVG 678

Query: 724 -----------------GASSVSLVPSLGLPSDQTPSLCPGLASGPPGAPG-PVKSGFEG 765
                            G+     +P +GLP    P   PG+  GPPGAPG P + G EG
Sbjct: 679 LPGDPGLPGQPGLPGIPGSKGEPGIPGIGLPGPPGPKGFPGI-PGPPGAPGTPGRIGLEG 737

Query: 766 YVELPPIEGRSPR------SPRNNPVPPEAKSPVLNPGERPADVSPTSPQPEGLLVLQ-Q 818
               P   G           P   P  P  K  +   G+R     P  P   GL  L   
Sbjct: 738 PPGPPGFPGPKGEPGFALPGPPGPPGLPGFKGALGPKGDRGFPGPPGPPGRTGLDGLPGP 797

Query: 819 VGDY-----------CFLPGLG----PGPLSLRSKPSSPGP--GPEIKNLDQAFQVKKPP 861
            GD              LPG+G    PGP      P  PGP   P +  +        PP
Sbjct: 798 KGDVGPNGQPGPMGPPGLPGIGVQGPPGP------PGIPGPIGQPGLHGIPGEKGDPGPP 851

Query: 862 GQAVPQVP 869
           G  VP  P
Sbjct: 852 GLDVPGPP 859



 Score = 53.1 bits (126), Expect = 1e-06
 Identities = 114/445 (25%), Positives = 147/445 (33%), Gaps = 104/445 (23%)

Query: 496 PPGSMSAF-TSGSPPHQGPWGSR-------FPELEGVFPVGFGDSEVSPLTIEDPKHVCD 547
           PPG        G P   GP G R       FP   G+  +   D    P  I      C+
Sbjct: 70  PPGPRGQKGDDGIPGPPGPKGIRGPPGLPGFPGTPGLPGMPGHDGAPGPQGIPG----CN 125

Query: 548 PPSGPDTTPAASDLPTEQPPSPQPGPPAASHTPEKQASSFDFNGP-----YLGPPHSRSL 602
              G    P +   P  Q P   PG P     P     S    GP     Y GPP  + L
Sbjct: 126 GTKGERGFPGSPGFPGLQGPPGPPGIPGMKGEPGSIIMS-SLPGPKGNPGYPGPPGIQGL 184

Query: 603 PDI------LGQPEPPQEGGSQKSP----PPGSLEYLCLPAGGQVQLVPLAQAMGPGQAV 652
           P        +G P PP   G    P    P G++        G+     L    GP   +
Sbjct: 185 PGPTGIPGPIGPPGPPGLMGPPGPPGLPGPKGNMGLNFQGPKGEKGEQGLQGPPGPPGQI 244

Query: 653 EVERRP-----SQGAAGSPSLESGGGPAPPAL----GPRVG-----------------GQ 686
             ++RP      +G  G P     G P PP +    GP  G                 G+
Sbjct: 245 SEQKRPIDVEFQKGDQGLPG--DRGPPGPPGIRGPPGPPGGEKGEKGEQGEPGKRGKPGK 302

Query: 687 DQKDSPVAIPMSSGDTEDPGVA-----------SGYVSSADLVFT-PNSGAS--SVSLVP 732
           D ++    IP   GD   PG             +G      LV   P +G +      + 
Sbjct: 303 DGENGQPGIPGLPGDPGYPGEPGRDGEKGQKGDTGPPGPPGLVIPRPGTGITIGEKGNIG 362

Query: 733 SLGLPSDQTPSLCPGLASGPPGAPGPVKS---------GFEG-------------YVELP 770
             GLP ++     PG+  GPPG PGP  +         GF G              +  P
Sbjct: 363 LPGLPGEKGERGFPGI-QGPPGLPGPPGAAVMGPPGPPGFPGERGQKGDEGPPGISIPGP 421

Query: 771 PIEGRSPRSPRNNPVPPEAKSPVLNPGERPADVSPT----SPQPEGLLVLQQV----GDY 822
           P     P +P   P PP    P + P +   +  P     SP  +GL   Q V    GD 
Sbjct: 422 PGLDGQPGAP-GLPGPPGPAGPHIPPSDEICEPGPPGPPGSPGDKGLQGEQGVKGDKGDT 480

Query: 823 CFLPGLGPGPLSLRSKPSSPG-PGP 846
           CF   +G G      +P  PG PGP
Sbjct: 481 CF-NCIGTGISGPPGQPGLPGLPGP 504



 Score = 51.2 bits (121), Expect = 4e-06
 Identities = 101/379 (26%), Positives = 127/379 (33%), Gaps = 93/379 (24%)

Query: 505  SGSPPHQGPWGSRF-PELEG----VFPVGFGDSEVSPLTIEDPKHVCDPP--SGPDTTPA 557
            SG P   GP G +  P L G    + P G   + +  +    P+ V  PP  SG    P 
Sbjct: 996  SGQPGLPGPPGPKGNPGLPGQPGLIGPPGLKGT-IGDMGFPGPQGVEGPPGPSGVPGQPG 1054

Query: 558  ASDLPTEQP-----------------PSPQPGPPAASHTPEKQASSFDFNGPYL-GPPHS 599
            +  LP ++                  P  +PG P     P  + S  D   P L G P +
Sbjct: 1055 SPGLPGQKGDKGDPGISSIGLPGLPGPKGEPGLPGYPGNPGIKGSVGDPGLPGLPGTPGA 1114

Query: 600  RSLPDILGQPEPPQEGGSQK-SPPPGS--LEYLCLPAGG---QVQLVPLAQAMGPGQAVE 653
            +  P + G P  P   G +  S PPG+  L     P GG     Q  P  +   PGQ   
Sbjct: 1115 KGQPGLPGFPGTPGPPGPKGISGPPGNPGLPGEPGPVGGGGHPGQPGPPGEKGKPGQDGI 1174

Query: 654  VERRPSQGAAGSPSLESGGGPAPPALGPRVGGQDQKDSPVAIPMSSGDTEDPGVASGYVS 713
                  +G  G P     G P PP L P + GQ             GD   PG+      
Sbjct: 1175 PGPAGQKGEPGQPGF---GNPGPPGL-PGLSGQ------------KGDGGLPGIPG---- 1214

Query: 714  SADLVFTPNSGASSVSLVPSL-GLPSDQTPSLCPGLASGPPGAPGPVKSGFEGYVELPPI 772
                    N G       P   G P  Q P        GPPG+PGP   G +G       
Sbjct: 1215 --------NPGLPGPKGEPGFHGFPGVQGPP-------GPPGSPGPALEGPKG------- 1252

Query: 773  EGRSPRSPRNNPVP------PEAKSPVLNPGERPADVSPTSPQPEGLLVLQQVGDYCFLP 826
                P+ P   P P      P  + P   PG         +P   GL           LP
Sbjct: 1253 -NPGPQGPPGRPGPTGFQGLPGPEGPPGLPGNGGIKGEKGNPGQPGL---------PGLP 1302

Query: 827  GL--GPGPLSLRSKPSSPG 843
            GL    GP  L+  P  PG
Sbjct: 1303 GLKGDQGPPGLQGNPGRPG 1321



 Score = 45.1 bits (105), Expect = 3e-04
 Identities = 81/306 (26%), Positives = 97/306 (31%), Gaps = 88/306 (28%)

Query: 551  GPDTTPAASDLPTEQPPSPQPGPPAASHTPEKQASSFDFNGPYLGPPHSRSLPDILGQPE 610
            GP   P     P  Q P   PGPP +              GP L  P     P   G P 
Sbjct: 1220 GPKGEPGFHGFPGVQGP---PGPPGSP-------------GPALEGPKGNPGPQ--GPPG 1261

Query: 611  PPQEGGSQKSP----PPGSLEYLCLPAGGQVQLVPLAQAMGPGQAVEVERRPSQGAAGSP 666
             P   G Q  P    PPG      LP  G ++     +   PGQ         +G  G P
Sbjct: 1262 RPGPTGFQGLPGPEGPPG------LPGNGGIK----GEKGNPGQPGLPGLPGLKGDQGPP 1311

Query: 667  SLESGGGPAPPALG--------PRVGGQDQKDSPVAIPMSSGDTEDPGVASGYVSSADLV 718
             L+  G P  P L         P V G      P  +P S+G   +PG          L+
Sbjct: 1312 GLQ--GNPGRPGLNGMKGDPGLPGVPGFPGMKGPSGVPGSAGPEGEPG----------LI 1359

Query: 719  FTPNSGASSVSLVPSLGLPSDQTPSLCPGLASGPPGAPGPVKSGFEGYVELPPIEGRSPR 778
              P             GLP     S+     +GPPG PG  + G +G   LP      P+
Sbjct: 1360 GPPGPP----------GLPGPSGQSIIIKGDAGPPGIPG--QPGLKG---LP-----GPQ 1399

Query: 779  SPRNNPVPPEAKSPVLNPGERPADVSPTSPQPEGLLVLQQVGDYCFLPGLGPGPLSLRSK 838
             P+  P P                  P  P   GL      G     PGL PG    R  
Sbjct: 1400 GPQGLPGPTG---------------PPGDPGRNGLPGFDGAGGRKGDPGL-PGQPGTRGL 1443

Query: 839  PSSPGP 844
               PGP
Sbjct: 1444 DGPPGP 1449



 Score = 35.0 bits (79), Expect = 0.31
 Identities = 26/79 (32%), Positives = 28/79 (35%), Gaps = 2/79 (2%)

Query: 549  PSGPDTTPAASDLPTEQPPSPQPGPPAASHTPEKQA-SSFDFNGPYLGPPHSRSLPDILG 607
            P G    P    LP  Q P   PGP      P +     FD  G   G P     P   G
Sbjct: 1383 PPGIPGQPGLKGLPGPQGPQGLPGPTGPPGDPGRNGLPGFDGAGGRKGDPGLPGQPGTRG 1442

Query: 608  QPEPPQEGGSQKSP-PPGS 625
               PP   G Q  P PPG+
Sbjct: 1443 LDGPPGPDGLQGPPGPPGT 1461


>gi|4502955 type IV collagen alpha 5 isoform 1 precursor [Homo
            sapiens]
          Length = 1685

 Score = 63.2 bits (152), Expect = 1e-09
 Identities = 116/399 (29%), Positives = 143/399 (35%), Gaps = 56/399 (14%)

Query: 478  IPNPSKSHLFQNGS-AELWPPGSMSAFTSGSPPHQG-PWGSRFPELEGVFPVGFGDSEVS 535
            +P P K  +  NG    + PPG       G P   G P     P L G+ P   GD    
Sbjct: 794  LPGP-KGDVGPNGQPGPMGPPGLPGIGVQGPPGPPGIPGPIGQPGLHGI-PGEKGDPGPP 851

Query: 536  PLTIEDPKHVCDPPSGPDTTPAASDLPTEQPPSPQ-PGPPAASHTPEKQASSFDFNGPY- 593
             L +  P      P  P         P   P SP  PG   AS  P  +        P  
Sbjct: 852  GLDVPGPPGERGSPGIPGAPG-----PIGPPGSPGLPGKAGASGFPGTKGEMGMMGPPGP 906

Query: 594  ---LGPPHSRSLPDILGQ---------PEPPQEGGSQKSP----PPGSLEYLCLPAGGQV 637
               LG P    +P + G          P P  E GS+  P    PPG ++   L + G+ 
Sbjct: 907  PGPLGIPGRSGVPGLKGDDGLQGQPGLPGPTGEKGSKGEPGLPGPPGPMDPNLLGSKGEK 966

Query: 638  Q---LVPLAQAMGPGQAVEVERRPSQ-GAAGSPSLESGGGPAPPALGPRVGGQDQKDSPV 693
                L  +    GP     +   P Q G +G P L    GP  P   P + GQ     P 
Sbjct: 967  GEPGLPGIPGVSGPKGYQGLPGDPGQPGLSGQPGLP---GPPGPKGNPGLPGQPGLIGPP 1023

Query: 694  AIPMSSGDTEDPGVASGYVSSADLVFTPNSGASSVSLVP-SLGLPSDQTPSLCPGLAS-G 751
             +  + GD   PG           V  P  G S V   P S GLP  +     PG++S G
Sbjct: 1024 GLKGTIGDMGFPGPQG--------VEGP-PGPSGVPGQPGSPGLPGQKGDKGDPGISSIG 1074

Query: 752  PPGAPGPV-KSGFEGYVELPPIEGR--SPRSPRNNPVPPEAKSPVLNPGERPADVSPTSP 808
             PG PGP  + G  GY   P I+G    P  P   P  P AK     PG       P +P
Sbjct: 1075 LPGLPGPKGEPGLPGYPGNPGIKGSVGDPGLP-GLPGTPGAKGQPGLPG------FPGTP 1127

Query: 809  QPEGLLVLQQVGDYCFLPGLGPGPLSLRSKPSSPGPGPE 847
             P G   +        LPG  PGP+     P  PGP  E
Sbjct: 1128 GPPGPKGISGPPGNPGLPG-EPGPVGGGGHPGQPGPPGE 1165



 Score = 53.9 bits (128), Expect = 7e-07
 Identities = 100/373 (26%), Positives = 126/373 (33%), Gaps = 87/373 (23%)

Query: 505  SGSPPHQGPWGSRF-PELEG----VFPVGFGDSEVSPLTIEDPKHVCDPP--SGPDTTPA 557
            SG P   GP G +  P L G    + P G   + +  +    P+ V  PP  SG    P 
Sbjct: 996  SGQPGLPGPPGPKGNPGLPGQPGLIGPPGLKGT-IGDMGFPGPQGVEGPPGPSGVPGQPG 1054

Query: 558  ASDLPTEQP-----------------PSPQPGPPAASHTPEKQASSFDFNGPYL-GPPHS 599
            +  LP ++                  P  +PG P     P  + S  D   P L G P +
Sbjct: 1055 SPGLPGQKGDKGDPGISSIGLPGLPGPKGEPGLPGYPGNPGIKGSVGDPGLPGLPGTPGA 1114

Query: 600  RSLPDILGQPEPPQEGGSQK-SPPPGS--LEYLCLPAGG---QVQLVPLAQAMGPGQAVE 653
            +  P + G P  P   G +  S PPG+  L     P GG     Q  P  +   PGQ   
Sbjct: 1115 KGQPGLPGFPGTPGPPGPKGISGPPGNPGLPGEPGPVGGGGHPGQPGPPGEKGKPGQDGI 1174

Query: 654  VERRPSQGAAGSPSLESGGGPAPPALGPRVGGQDQKDSPVAIPMSSGDTEDPGVASGYVS 713
                  +G  G P     G P PP L P + GQ             GD   PG+      
Sbjct: 1175 PGPAGQKGEPGQPGF---GNPGPPGL-PGLSGQ------------KGDGGLPGIPG---- 1214

Query: 714  SADLVFTPNSGASSVSLVPSL-GLPSDQTPSLCPGLASGPPGAPGPVKSGFEGYVELPPI 772
                    N G       P   G P  Q P        GPPG+PGP   G +G       
Sbjct: 1215 --------NPGLPGPKGEPGFHGFPGVQGPP-------GPPGSPGPALEGPKG------- 1252

Query: 773  EGRSPRSPRNNPVPPEAKSPVLNPGERPADVSPTSPQPEGLLVLQQVGDYCFLPGL--GP 830
                P+ P   P  P  + P   PG         +P   GL           LPGL    
Sbjct: 1253 -NPGPQGPPGRPGLPGPEGPPGLPGNGGIKGEKGNPGQPGL---------PGLPGLKGDQ 1302

Query: 831  GPLSLRSKPSSPG 843
            GP  L+  P  PG
Sbjct: 1303 GPPGLQGNPGRPG 1315



 Score = 53.5 bits (127), Expect = 8e-07
 Identities = 126/488 (25%), Positives = 148/488 (30%), Gaps = 125/488 (25%)

Query: 490 GSAELWPPGSMS-AFTSGSPPHQGPWGSRFPELEGVF----------PVGFGDSEVSPLT 538
           G+A + PPG        G    +GP G   P   G+           P G     + P  
Sbjct: 389 GAAVMGPPGPPGFPGERGQKGDEGPPGISIPGPPGLDGQPGAPGLPGPPGPAGPHIPP-- 446

Query: 539 IEDPKHVCDP-PSGPDTTPAASDLPTEQP-------------------PSPQPGPPAASH 578
                 +C+P P GP  +P    L  EQ                    P  QPG P    
Sbjct: 447 ---SDEICEPGPPGPPGSPGDKGLQGEQGVKGDKGDTCFNCIGTGISGPPGQPGLPGLPG 503

Query: 579 TPEKQASSFDFNGP-----YLGPPHSRSLPDILGQPEPPQEGGSQKSP------------ 621
            P     S  F G        G    + LP I G P  P   GS+  P            
Sbjct: 504 PP----GSLGFPGQKGEKGQAGATGPKGLPGIPGAPGAPGFPGSKGEPGDILTFPGMKGD 559

Query: 622 -----PPGSLEYLCLPAG-GQVQLVPLAQAMG-PGQAVEVERRPSQGAAGSPSLESGGGP 674
                 PG+     LP   GQ  L  L    G PG       R   G  G P L    GP
Sbjct: 560 KGELGSPGAPGLPGLPGTPGQDGLPGLPGPKGEPGGITFKGERGPPGNPGLPGLPGNIGP 619

Query: 675 -APPALGP-----RVGGQDQKDSPVAIPMSSGDTEDPGVASGYVSSADLVFTPNS----- 723
             PP  GP       G Q    +P   P   G   DPG          L   P       
Sbjct: 620 MGPPGFGPPGPVGEKGIQGVAGNP-GQPGIPGPKGDPGQTITQPGKPGLPGNPGRDGDVG 678

Query: 724 -----------------GASSVSLVPSLGLPSDQTPSLCPGLASGPPGAPG-PVKSGFEG 765
                            G+     +P +GLP    P   PG+  GPPGAPG P + G EG
Sbjct: 679 LPGDPGLPGQPGLPGIPGSKGEPGIPGIGLPGPPGPKGFPGI-PGPPGAPGTPGRIGLEG 737

Query: 766 YVELPPIEGRSPR------SPRNNPVPPEAKSPVLNPGERPADVSPTSPQPEGLLVLQ-Q 818
               P   G           P   P  P  K  +   G+R     P  P   GL  L   
Sbjct: 738 PPGPPGFPGPKGEPGFALPGPPGPPGLPGFKGALGPKGDRGFPGPPGPPGRTGLDGLPGP 797

Query: 819 VGDY-----------CFLPGLG----PGPLSLRSKPSSPGP--GPEIKNLDQAFQVKKPP 861
            GD              LPG+G    PGP      P  PGP   P +  +        PP
Sbjct: 798 KGDVGPNGQPGPMGPPGLPGIGVQGPPGP------PGIPGPIGQPGLHGIPGEKGDPGPP 851

Query: 862 GQAVPQVP 869
           G  VP  P
Sbjct: 852 GLDVPGPP 859



 Score = 53.1 bits (126), Expect = 1e-06
 Identities = 114/445 (25%), Positives = 147/445 (33%), Gaps = 104/445 (23%)

Query: 496 PPGSMSAF-TSGSPPHQGPWGSR-------FPELEGVFPVGFGDSEVSPLTIEDPKHVCD 547
           PPG        G P   GP G R       FP   G+  +   D    P  I      C+
Sbjct: 70  PPGPRGQKGDDGIPGPPGPKGIRGPPGLPGFPGTPGLPGMPGHDGAPGPQGIPG----CN 125

Query: 548 PPSGPDTTPAASDLPTEQPPSPQPGPPAASHTPEKQASSFDFNGP-----YLGPPHSRSL 602
              G    P +   P  Q P   PG P     P     S    GP     Y GPP  + L
Sbjct: 126 GTKGERGFPGSPGFPGLQGPPGPPGIPGMKGEPGSIIMS-SLPGPKGNPGYPGPPGIQGL 184

Query: 603 PDI------LGQPEPPQEGGSQKSP----PPGSLEYLCLPAGGQVQLVPLAQAMGPGQAV 652
           P        +G P PP   G    P    P G++        G+     L    GP   +
Sbjct: 185 PGPTGIPGPIGPPGPPGLMGPPGPPGLPGPKGNMGLNFQGPKGEKGEQGLQGPPGPPGQI 244

Query: 653 EVERRP-----SQGAAGSPSLESGGGPAPPAL----GPRVG-----------------GQ 686
             ++RP      +G  G P     G P PP +    GP  G                 G+
Sbjct: 245 SEQKRPIDVEFQKGDQGLPG--DRGPPGPPGIRGPPGPPGGEKGEKGEQGEPGKRGKPGK 302

Query: 687 DQKDSPVAIPMSSGDTEDPGVA-----------SGYVSSADLVFT-PNSGAS--SVSLVP 732
           D ++    IP   GD   PG             +G      LV   P +G +      + 
Sbjct: 303 DGENGQPGIPGLPGDPGYPGEPGRDGEKGQKGDTGPPGPPGLVIPRPGTGITIGEKGNIG 362

Query: 733 SLGLPSDQTPSLCPGLASGPPGAPGPVKS---------GFEG-------------YVELP 770
             GLP ++     PG+  GPPG PGP  +         GF G              +  P
Sbjct: 363 LPGLPGEKGERGFPGI-QGPPGLPGPPGAAVMGPPGPPGFPGERGQKGDEGPPGISIPGP 421

Query: 771 PIEGRSPRSPRNNPVPPEAKSPVLNPGERPADVSPT----SPQPEGLLVLQQV----GDY 822
           P     P +P   P PP    P + P +   +  P     SP  +GL   Q V    GD 
Sbjct: 422 PGLDGQPGAP-GLPGPPGPAGPHIPPSDEICEPGPPGPPGSPGDKGLQGEQGVKGDKGDT 480

Query: 823 CFLPGLGPGPLSLRSKPSSPG-PGP 846
           CF   +G G      +P  PG PGP
Sbjct: 481 CF-NCIGTGISGPPGQPGLPGLPGP 504



 Score = 43.9 bits (102), Expect = 7e-04
 Identities = 82/297 (27%), Positives = 95/297 (31%), Gaps = 76/297 (25%)

Query: 551  GPDTTPAASDLPTEQ-PPSPQPGPPAASHTPEKQASSFDFNGPYLGPPHSRSLPDILGQP 609
            GP   P     P  Q PP P   P  A   P+         GP  GPP    LP   G P
Sbjct: 1220 GPKGEPGFHGFPGVQGPPGPPGSPGPALEGPKGNP------GPQ-GPPGRPGLPGPEGPP 1272

Query: 610  EPPQEGG--SQKSPPPGSLEYLCLPAGGQVQLVPLAQAMGPGQAVEVERRPSQGAAGSPS 667
              P  GG   +K  P            GQ  L  L     PG   +      QG  G P 
Sbjct: 1273 GLPGNGGIKGEKGNP------------GQPGLPGL-----PGLKGDQGPPGLQGNPGRPG 1315

Query: 668  LESGGGPAPPALGPRVGGQDQKDSPVAIPMSSGDTEDPGVASGYVSSADLVFTPNSGASS 727
            L   G    P L P V G      P  +P S+G   +PG          L+  P      
Sbjct: 1316 LN--GMKGDPGL-PGVPGFPGMKGPSGVPGSAGPEGEPG----------LIGPPGPP--- 1359

Query: 728  VSLVPSLGLPSDQTPSLCPGLASGPPGAPGPVKSGFEGYVELPPIEGRSPRSPRNNPVPP 787
                   GLP     S+     +GPPG PG  + G +G   LP      P+ P+  P P 
Sbjct: 1360 -------GLPGPSGQSIIIKGDAGPPGIPG--QPGLKG---LP-----GPQGPQGLPGPT 1402

Query: 788  EAKSPVLNPGERPADVSPTSPQPEGLLVLQQVGDYCFLPGLGPGPLSLRSKPSSPGP 844
                             P  P   GL      G     PGL PG    R     PGP
Sbjct: 1403 G---------------PPGDPGRNGLPGFDGAGGRKGDPGL-PGQPGTRGLDGPPGP 1443



 Score = 35.0 bits (79), Expect = 0.31
 Identities = 26/79 (32%), Positives = 28/79 (35%), Gaps = 2/79 (2%)

Query: 549  PSGPDTTPAASDLPTEQPPSPQPGPPAASHTPEKQA-SSFDFNGPYLGPPHSRSLPDILG 607
            P G    P    LP  Q P   PGP      P +     FD  G   G P     P   G
Sbjct: 1377 PPGIPGQPGLKGLPGPQGPQGLPGPTGPPGDPGRNGLPGFDGAGGRKGDPGLPGQPGTRG 1436

Query: 608  QPEPPQEGGSQKSP-PPGS 625
               PP   G Q  P PPG+
Sbjct: 1437 LDGPPGPDGLQGPPGPPGT 1455


>gi|15890088 type IV collagen alpha 5 isoform 3 precursor [Homo
            sapiens]
          Length = 1688

 Score = 63.2 bits (152), Expect = 1e-09
 Identities = 116/399 (29%), Positives = 143/399 (35%), Gaps = 56/399 (14%)

Query: 478  IPNPSKSHLFQNGS-AELWPPGSMSAFTSGSPPHQG-PWGSRFPELEGVFPVGFGDSEVS 535
            +P P K  +  NG    + PPG       G P   G P     P L G+ P   GD    
Sbjct: 794  LPGP-KGDVGPNGQPGPMGPPGLPGIGVQGPPGPPGIPGPIGQPGLHGI-PGEKGDPGPP 851

Query: 536  PLTIEDPKHVCDPPSGPDTTPAASDLPTEQPPSPQ-PGPPAASHTPEKQASSFDFNGPY- 593
             L +  P      P  P         P   P SP  PG   AS  P  +        P  
Sbjct: 852  GLDVPGPPGERGSPGIPGAPG-----PIGPPGSPGLPGKAGASGFPGTKGEMGMMGPPGP 906

Query: 594  ---LGPPHSRSLPDILGQ---------PEPPQEGGSQKSP----PPGSLEYLCLPAGGQV 637
               LG P    +P + G          P P  E GS+  P    PPG ++   L + G+ 
Sbjct: 907  PGPLGIPGRSGVPGLKGDDGLQGQPGLPGPTGEKGSKGEPGLPGPPGPMDPNLLGSKGEK 966

Query: 638  Q---LVPLAQAMGPGQAVEVERRPSQ-GAAGSPSLESGGGPAPPALGPRVGGQDQKDSPV 693
                L  +    GP     +   P Q G +G P L    GP  P   P + GQ     P 
Sbjct: 967  GEPGLPGIPGVSGPKGYQGLPGDPGQPGLSGQPGLP---GPPGPKGNPGLPGQPGLIGPP 1023

Query: 694  AIPMSSGDTEDPGVASGYVSSADLVFTPNSGASSVSLVP-SLGLPSDQTPSLCPGLAS-G 751
             +  + GD   PG           V  P  G S V   P S GLP  +     PG++S G
Sbjct: 1024 GLKGTIGDMGFPGPQG--------VEGP-PGPSGVPGQPGSPGLPGQKGDKGDPGISSIG 1074

Query: 752  PPGAPGPV-KSGFEGYVELPPIEGR--SPRSPRNNPVPPEAKSPVLNPGERPADVSPTSP 808
             PG PGP  + G  GY   P I+G    P  P   P  P AK     PG       P +P
Sbjct: 1075 LPGLPGPKGEPGLPGYPGNPGIKGSVGDPGLP-GLPGTPGAKGQPGLPG------FPGTP 1127

Query: 809  QPEGLLVLQQVGDYCFLPGLGPGPLSLRSKPSSPGPGPE 847
             P G   +        LPG  PGP+     P  PGP  E
Sbjct: 1128 GPPGPKGISGPPGNPGLPG-EPGPVGGGGHPGQPGPPGE 1165



 Score = 53.5 bits (127), Expect = 8e-07
 Identities = 126/488 (25%), Positives = 148/488 (30%), Gaps = 125/488 (25%)

Query: 490 GSAELWPPGSMS-AFTSGSPPHQGPWGSRFPELEGVF----------PVGFGDSEVSPLT 538
           G+A + PPG        G    +GP G   P   G+           P G     + P  
Sbjct: 389 GAAVMGPPGPPGFPGERGQKGDEGPPGISIPGPPGLDGQPGAPGLPGPPGPAGPHIPP-- 446

Query: 539 IEDPKHVCDP-PSGPDTTPAASDLPTEQP-------------------PSPQPGPPAASH 578
                 +C+P P GP  +P    L  EQ                    P  QPG P    
Sbjct: 447 ---SDEICEPGPPGPPGSPGDKGLQGEQGVKGDKGDTCFNCIGTGISGPPGQPGLPGLPG 503

Query: 579 TPEKQASSFDFNGP-----YLGPPHSRSLPDILGQPEPPQEGGSQKSP------------ 621
            P     S  F G        G    + LP I G P  P   GS+  P            
Sbjct: 504 PP----GSLGFPGQKGEKGQAGATGPKGLPGIPGAPGAPGFPGSKGEPGDILTFPGMKGD 559

Query: 622 -----PPGSLEYLCLPAG-GQVQLVPLAQAMG-PGQAVEVERRPSQGAAGSPSLESGGGP 674
                 PG+     LP   GQ  L  L    G PG       R   G  G P L    GP
Sbjct: 560 KGELGSPGAPGLPGLPGTPGQDGLPGLPGPKGEPGGITFKGERGPPGNPGLPGLPGNIGP 619

Query: 675 -APPALGP-----RVGGQDQKDSPVAIPMSSGDTEDPGVASGYVSSADLVFTPNS----- 723
             PP  GP       G Q    +P   P   G   DPG          L   P       
Sbjct: 620 MGPPGFGPPGPVGEKGIQGVAGNP-GQPGIPGPKGDPGQTITQPGKPGLPGNPGRDGDVG 678

Query: 724 -----------------GASSVSLVPSLGLPSDQTPSLCPGLASGPPGAPG-PVKSGFEG 765
                            G+     +P +GLP    P   PG+  GPPGAPG P + G EG
Sbjct: 679 LPGDPGLPGQPGLPGIPGSKGEPGIPGIGLPGPPGPKGFPGI-PGPPGAPGTPGRIGLEG 737

Query: 766 YVELPPIEGRSPR------SPRNNPVPPEAKSPVLNPGERPADVSPTSPQPEGLLVLQ-Q 818
               P   G           P   P  P  K  +   G+R     P  P   GL  L   
Sbjct: 738 PPGPPGFPGPKGEPGFALPGPPGPPGLPGFKGALGPKGDRGFPGPPGPPGRTGLDGLPGP 797

Query: 819 VGDY-----------CFLPGLG----PGPLSLRSKPSSPGP--GPEIKNLDQAFQVKKPP 861
            GD              LPG+G    PGP      P  PGP   P +  +        PP
Sbjct: 798 KGDVGPNGQPGPMGPPGLPGIGVQGPPGP------PGIPGPIGQPGLHGIPGEKGDPGPP 851

Query: 862 GQAVPQVP 869
           G  VP  P
Sbjct: 852 GLDVPGPP 859



 Score = 53.1 bits (126), Expect = 1e-06
 Identities = 114/445 (25%), Positives = 147/445 (33%), Gaps = 104/445 (23%)

Query: 496 PPGSMSAF-TSGSPPHQGPWGSR-------FPELEGVFPVGFGDSEVSPLTIEDPKHVCD 547
           PPG        G P   GP G R       FP   G+  +   D    P  I      C+
Sbjct: 70  PPGPRGQKGDDGIPGPPGPKGIRGPPGLPGFPGTPGLPGMPGHDGAPGPQGIPG----CN 125

Query: 548 PPSGPDTTPAASDLPTEQPPSPQPGPPAASHTPEKQASSFDFNGP-----YLGPPHSRSL 602
              G    P +   P  Q P   PG P     P     S    GP     Y GPP  + L
Sbjct: 126 GTKGERGFPGSPGFPGLQGPPGPPGIPGMKGEPGSIIMS-SLPGPKGNPGYPGPPGIQGL 184

Query: 603 PDI------LGQPEPPQEGGSQKSP----PPGSLEYLCLPAGGQVQLVPLAQAMGPGQAV 652
           P        +G P PP   G    P    P G++        G+     L    GP   +
Sbjct: 185 PGPTGIPGPIGPPGPPGLMGPPGPPGLPGPKGNMGLNFQGPKGEKGEQGLQGPPGPPGQI 244

Query: 653 EVERRP-----SQGAAGSPSLESGGGPAPPAL----GPRVG-----------------GQ 686
             ++RP      +G  G P     G P PP +    GP  G                 G+
Sbjct: 245 SEQKRPIDVEFQKGDQGLPG--DRGPPGPPGIRGPPGPPGGEKGEKGEQGEPGKRGKPGK 302

Query: 687 DQKDSPVAIPMSSGDTEDPGVA-----------SGYVSSADLVFT-PNSGAS--SVSLVP 732
           D ++    IP   GD   PG             +G      LV   P +G +      + 
Sbjct: 303 DGENGQPGIPGLPGDPGYPGEPGRDGEKGQKGDTGPPGPPGLVIPRPGTGITIGEKGNIG 362

Query: 733 SLGLPSDQTPSLCPGLASGPPGAPGPVKS---------GFEG-------------YVELP 770
             GLP ++     PG+  GPPG PGP  +         GF G              +  P
Sbjct: 363 LPGLPGEKGERGFPGI-QGPPGLPGPPGAAVMGPPGPPGFPGERGQKGDEGPPGISIPGP 421

Query: 771 PIEGRSPRSPRNNPVPPEAKSPVLNPGERPADVSPT----SPQPEGLLVLQQV----GDY 822
           P     P +P   P PP    P + P +   +  P     SP  +GL   Q V    GD 
Sbjct: 422 PGLDGQPGAP-GLPGPPGPAGPHIPPSDEICEPGPPGPPGSPGDKGLQGEQGVKGDKGDT 480

Query: 823 CFLPGLGPGPLSLRSKPSSPG-PGP 846
           CF   +G G      +P  PG PGP
Sbjct: 481 CF-NCIGTGISGPPGQPGLPGLPGP 504



 Score = 49.3 bits (116), Expect = 2e-05
 Identities = 102/375 (27%), Positives = 129/375 (34%), Gaps = 88/375 (23%)

Query: 505  SGSPPHQGPWGSRF-PELEG----VFPVGFGDSEVSPLTIEDPKHVCDPP--SGPDTTPA 557
            SG P   GP G +  P L G    + P G   + +  +    P+ V  PP  SG    P 
Sbjct: 996  SGQPGLPGPPGPKGNPGLPGQPGLIGPPGLKGT-IGDMGFPGPQGVEGPPGPSGVPGQPG 1054

Query: 558  ASDLPTEQP-----------------PSPQPGPPAASHTPEKQASSFDFNGPYL-GPPHS 599
            +  LP ++                  P  +PG P     P  + S  D   P L G P +
Sbjct: 1055 SPGLPGQKGDKGDPGISSIGLPGLPGPKGEPGLPGYPGNPGIKGSVGDPGLPGLPGTPGA 1114

Query: 600  RSLPDILGQPEPPQEGGSQK-SPPPGS--LEYLCLPAGG---QVQLVPLAQAMGPGQAVE 653
            +  P + G P  P   G +  S PPG+  L     P GG     Q  P  +   PGQ   
Sbjct: 1115 KGQPGLPGFPGTPGPPGPKGISGPPGNPGLPGEPGPVGGGGHPGQPGPPGEKGKPGQDGI 1174

Query: 654  VERRPSQGAAGSPSLESGGGPAPPALGPRVGGQDQKDSPVAIPMSSGDTEDPGVASGYVS 713
                  +G  G P     G P PP L P + GQ             GD   PG+      
Sbjct: 1175 PGPAGQKGEPGQPGF---GNPGPPGL-PGLSGQ------------KGDGGLPGIPG---- 1214

Query: 714  SADLVFTPNSGASSVSLVPSL-GLPSDQTPSLCPGLASGPPGAPGPVKSGFEGYVELPPI 772
                    N G       P   G P  Q P        GPPG+PGP   G +G    P  
Sbjct: 1215 --------NPGLPGPKGEPGFHGFPGVQGPP-------GPPGSPGPALEGPKGN---PGP 1256

Query: 773  EGRSPRSPRNNPVPPEAKSPVL--NPGERPADVSPTSPQPEGLLVLQQVGDYCFLPGL-- 828
            +G  P  P    +P     P L  N G +    +P  P   G            LPGL  
Sbjct: 1257 QG-PPGRPGFQGLPGPEGPPGLPGNGGIKGEKGNPGQPGLPG------------LPGLKG 1303

Query: 829  GPGPLSLRSKPSSPG 843
              GP  L+  P  PG
Sbjct: 1304 DQGPPGLQGNPGRPG 1318



 Score = 43.5 bits (101), Expect = 9e-04
 Identities = 80/306 (26%), Positives = 96/306 (31%), Gaps = 91/306 (29%)

Query: 551  GPDTTPAASDLPTEQPPSPQPGPPAASHTPEKQASSFDFNGPYLGPPHSRSLPDILGQPE 610
            GP   P     P  Q P   PGPP +              GP L  P         G   
Sbjct: 1220 GPKGEPGFHGFPGVQGP---PGPPGSP-------------GPALEGPKGNP-----GPQG 1258

Query: 611  PPQEGGSQKSP----PPGSLEYLCLPAGGQVQLVPLAQAMGPGQAVEVERRPSQGAAGSP 666
            PP   G Q  P    PPG      LP  G ++     +   PGQ         +G  G P
Sbjct: 1259 PPGRPGFQGLPGPEGPPG------LPGNGGIK----GEKGNPGQPGLPGLPGLKGDQGPP 1308

Query: 667  SLESGGGPAPPALG--------PRVGGQDQKDSPVAIPMSSGDTEDPGVASGYVSSADLV 718
             L+  G P  P L         P V G      P  +P S+G   +PG          L+
Sbjct: 1309 GLQ--GNPGRPGLNGMKGDPGLPGVPGFPGMKGPSGVPGSAGPEGEPG----------LI 1356

Query: 719  FTPNSGASSVSLVPSLGLPSDQTPSLCPGLASGPPGAPGPVKSGFEGYVELPPIEGRSPR 778
              P             GLP     S+     +GPPG PG  + G +G   LP      P+
Sbjct: 1357 GPPGPP----------GLPGPSGQSIIIKGDAGPPGIPG--QPGLKG---LP-----GPQ 1396

Query: 779  SPRNNPVPPEAKSPVLNPGERPADVSPTSPQPEGLLVLQQVGDYCFLPGLGPGPLSLRSK 838
             P+  P P                  P  P   GL      G     PGL PG    R  
Sbjct: 1397 GPQGLPGPTG---------------PPGDPGRNGLPGFDGAGGRKGDPGL-PGQPGTRGL 1440

Query: 839  PSSPGP 844
               PGP
Sbjct: 1441 DGPPGP 1446



 Score = 35.0 bits (79), Expect = 0.31
 Identities = 26/79 (32%), Positives = 28/79 (35%), Gaps = 2/79 (2%)

Query: 549  PSGPDTTPAASDLPTEQPPSPQPGPPAASHTPEKQA-SSFDFNGPYLGPPHSRSLPDILG 607
            P G    P    LP  Q P   PGP      P +     FD  G   G P     P   G
Sbjct: 1380 PPGIPGQPGLKGLPGPQGPQGLPGPTGPPGDPGRNGLPGFDGAGGRKGDPGLPGQPGTRG 1439

Query: 608  QPEPPQEGGSQKSP-PPGS 625
               PP   G Q  P PPG+
Sbjct: 1440 LDGPPGPDGLQGPPGPPGT 1458


>gi|146219843 Snf2-related CBP activator protein [Homo sapiens]
          Length = 3230

 Score = 62.8 bits (151), Expect = 1e-09
 Identities = 87/310 (28%), Positives = 112/310 (36%), Gaps = 41/310 (13%)

Query: 535  SPLTIEDPKHVCDPPSGPDTTPAASDLPTEQPPSPQPGPPAASHTPEKQASSFDFNGPYL 594
            +PLTI  P HV      P + P  +  P   P S     P +S      +SS   + P  
Sbjct: 1393 APLTISSPLHV------PSSLPGPASSPMPIPNSSPLASPVSSTVSVPLSSSLPISVPTT 1446

Query: 595  GP-PHSRSLPDILGQPEPPQEGGSQKSPPPGSLEYLCLPAGGQVQLVPLAQAMGPGQAVE 653
             P P S  L   +  P      G      P  L  +  P    V   P   ++ P  A  
Sbjct: 1447 LPAPASAPLTIPISAPLTVSASG------PALLTSVTPPLAPVVPAAPGPPSLAPSGASP 1500

Query: 654  VERRPSQGAAGSPSLESGGGPAPPAL----GPRVGGQDQ----KDSPVAIPMSSGDTEDP 705
                 + G A +PSL S   P  P L       V G +       SPV +P S+  +  P
Sbjct: 1501 SASALTLGLATAPSLSSSQTPGHPLLLAPTSSHVPGLNSTVAPACSPVLVPASALASPFP 1560

Query: 706  GVASGYVSSADLVFTPNSGASSVSLVPSLGLPSDQTPSLCPGLASGPPGAPGPVKSGFEG 765
               +   + A L+  P S AS     P   + + QT  L P  A  PP AP PV      
Sbjct: 1561 SAPNPAPAQASLL-APASSASQALATPLAPMAAPQTAILAPSPA--PPLAPLPV------ 1611

Query: 766  YVELPPIEGRSP-RSPRNNPVPPEAKSPVLNPGERPADVSPT-SPQPEGLLVLQQVGDYC 823
               L P  G +P  +    PVP    +P   PG   A  SP  +P P    VL       
Sbjct: 1612 ---LAPSPGAAPVLASSQTPVP--VMAPSSTPGTSLASASPVPAPTP----VLAPSSTQT 1662

Query: 824  FLPGLGPGPL 833
             LP   P PL
Sbjct: 1663 MLPAPVPSPL 1672



 Score = 50.4 bits (119), Expect = 7e-06
 Identities = 96/386 (24%), Positives = 134/386 (34%), Gaps = 78/386 (20%)

Query: 497  PGSMSAFTSGSPPHQGPWGSRFPELEGVFPVGFGDSEVSPLTIEDPKHVCDPPSGPDTTP 556
            P   S+ T G P    P  S  P L         +S V+P         C P   P    
Sbjct: 1513 PSLSSSQTPGHPLLLAPTSSHVPGL---------NSTVAP--------ACSPVLVP---- 1551

Query: 557  AASDLPTEQPPSPQPGPPAASHTPEKQASSFDFNGPYLGPPHSRSLPDILGQPEPPQEGG 616
             AS L +  P +P P P  AS      ++S     P L P  +     +   P PP    
Sbjct: 1552 -ASALASPFPSAPNPAPAQASLLAPASSASQALATP-LAPMAAPQTAILAPSPAPPLAPL 1609

Query: 617  SQKSPPPGSLEYLCLPAGGQVQLVPLAQAMGPGQAV-EVERRPSQGAAGSPSLESGGGPA 675
               +P PG+   L   A  Q  +  +A +  PG ++      P+     +PS      PA
Sbjct: 1610 PVLAPSPGAAPVL---ASSQTPVPVMAPSSTPGTSLASASPVPAPTPVLAPSSTQTMLPA 1666

Query: 676  P-----------------PALGPRVGGQDQKDSPVAIPMSSGDTEDPGVAS--GYVSSAD 716
            P                 PAL P +GG     +   + + +G+ + P          ++ 
Sbjct: 1667 PVPSPLPSPASTQTLALAPALAPTLGGSSPSQT---LSLGTGNPQGPFPTQTLSLTPASS 1723

Query: 717  LVFTPNSGASSVSLVPSLGLPSDQTPSLCPG--LASGPPGAPGPVKSGFEGYVELPPIEG 774
            LV TP   A ++SL P   L   QT SL P   LA   P  P P  +     + L P   
Sbjct: 1724 LVPTP---AQTLSLAPGPPLGPTQTLSLAPAPPLAPASPVGPAPAHT-----LTLAPASS 1775

Query: 775  R----SPRSPRNNPVPPEAKSPVLNPGERP----ADVSPTSPQPEGLLVLQQVGDYCFLP 826
                 +P S +   + P A  P L P        A  S  SP  +   ++        LP
Sbjct: 1776 SASLLAPASVQTLTLSP-APVPTLGPAAAQTLALAPASTQSPASQASSLVVSASGAAPLP 1834

Query: 827  GL----------GPGPLSLRSKPSSP 842
                         P  L+LRS P SP
Sbjct: 1835 VTMVSRLPVSKDEPDTLTLRSGPPSP 1860



 Score = 45.4 bits (106), Expect = 2e-04
 Identities = 92/346 (26%), Positives = 120/346 (34%), Gaps = 72/346 (20%)

Query: 530  GDSEVSPLTIEDPKHVCDPPSGPDTTPAASDLPTEQPPSPQP-------GPPAASHTPEK 582
            G S  S   +  P  V  P S     PA    P   P S Q         P     +P +
Sbjct: 1639 GTSLASASPVPAPTPVLAPSSTQTMLPAPVPSPLPSPASTQTLALAPALAPTLGGSSPSQ 1698

Query: 583  QASSFDFN--GPYLGPPHSRSL-PDILGQPEPPQEGGSQKSPPPGSLEYLCLPAGGQVQL 639
              S    N  GP+  P  + SL P     P P Q       PP G  + L L        
Sbjct: 1699 TLSLGTGNPQGPF--PTQTLSLTPASSLVPTPAQTLSLAPGPPLGPTQTLSLAPAP---- 1752

Query: 640  VPLAQA--MGPGQAVEVERRPSQGAAGSPSLESGG----GPAP-PALGPRVGGQDQKDSP 692
             PLA A  +GP  A  +   P+  +A   +  S       PAP P LGP           
Sbjct: 1753 -PLAPASPVGPAPAHTLTLAPASSSASLLAPASVQTLTLSPAPVPTLGPAAAQ------- 1804

Query: 693  VAIPMSSGDTEDPGVASGYVSSADLVFTPNSGASS--VSLVPSLGLPSDQTPSLCPGLAS 750
              + ++   T+ P       S A  +    SGA+   V++V  L +  D+  +L   L S
Sbjct: 1805 -TLALAPASTQSPA------SQASSLVVSASGAAPLPVTMVSRLPVSKDEPDTLT--LRS 1855

Query: 751  GPPGAPGPVKSGFEGYVELPPIEGRSPRSPRNNPVPPEAKSPVLNPGERPADVSPTSPQP 810
            GPP  P    S F G           PR PR  P PP  +SP              S + 
Sbjct: 1856 GPPSPPSTATS-FGG-----------PR-PRRQP-PPPPRSPFYLDSLEEKRKRQRSERL 1901

Query: 811  EGLLVLQ------------QVGDYCFLPGLGPGPLSLRSKPSSPGP 844
            E +  L             +V D+C LP     P+     P SPGP
Sbjct: 1902 ERIFQLSEAHGALAPVYGTEVLDFCTLPQPVASPIG----PRSPGP 1943



 Score = 38.5 bits (88), Expect = 0.028
 Identities = 83/324 (25%), Positives = 116/324 (35%), Gaps = 57/324 (17%)

Query: 532  SEVSPLTIEDPKHVCDPPSGPDTTPAASDLPTEQPPSPQPGPPAASHTPEKQASSFDFNG 591
            S  +P+TI  P H+   P  P   P  S      PP+  P PPA +  P +       + 
Sbjct: 2469 SAPNPITIL-PVHILPSPPPPSQIPPCSSPACTPPPACTP-PPAHTPPPAQTCLVTPSSP 2526

Query: 592  PYLGPPH---SRSLPDILGQPEPPQEGGSQKSPPPGSLEYLCLPAG--------GQVQLV 640
              LGPP    S S+ ++     P  E  +Q    P SLE   + +             L+
Sbjct: 2527 LLLGPPSVPISASVTNLPLGLRPEAELCAQALASPESLELASVASSETSSLSLVPPKDLL 2586

Query: 641  PLAQAMGPGQAVEVERRPSQGAAGSPSLESGGGPAPPALGPRVGGQDQKDSPVAIPMSSG 700
            P+A  + P     +   PS   A S +LE+G  P          GQ+Q+      P S+ 
Sbjct: 2587 PVAVEILPVSEKNLSLTPS---APSLTLEAGSIP---------NGQEQE-----APDSAE 2629

Query: 701  DTEDPGVASG-----YVSSADLVFTPNSGASSVSLVPSLGLPSDQTPSLCPGLASGPPGA 755
             T    +  G      VS ++ +  P S AS   L     L +D+T       A  P  +
Sbjct: 2630 GTTLTVLPEGEELPLCVSESNGLELPPSAASDEPLQEP--LEADRTSEELTE-AKTPTSS 2686

Query: 756  PGPVKSGFEGYVELPPIEGRSPRSPRNNPVPPEAKSPVLNPGERPADVSPTSPQPEGLLV 815
            P       E   EL   E  +P +  +    PE  SP   P  R +       Q  G   
Sbjct: 2687 P-------EKPQELVTAEVAAPSTSSSATSSPEGPSPARPPRRRTSADVEIRGQGTG--- 2736

Query: 816  LQQVGDYCFLPGLGPGPLSLRSKP 839
                      PG  PGP  LR  P
Sbjct: 2737 ---------RPGQPPGPKVLRKLP 2751



 Score = 32.0 bits (71), Expect = 2.6
 Identities = 103/427 (24%), Positives = 141/427 (33%), Gaps = 130/427 (30%)

Query: 548  PPSGPDTT------PAASDLPTEQPPSPQP-GPPA--ASHTPEKQASSFDFNGPYLGPP- 597
            PP GP+ +      P    LP     S  P GPP   AS  P          GP L PP 
Sbjct: 1026 PPPGPELSAQPTPGPVPQVLPASLMVSASPAGPPLIPASRPP----------GPVLLPPL 1075

Query: 598  --HSRSLPDILG-------------------QPEPPQEGGSQKSPPPGS---LEYLCLPA 633
              +S SLP +L                    +P PP       +PPPGS   L+ L +P 
Sbjct: 1076 QPNSGSLPQVLPSPLGVLSGTSRPPTPTLSLKPTPPAPVRLSPAPPPGSSSLLKPLTVPP 1135

Query: 634  G------------------------------GQVQLVPLAQAMGP-------GQAVEVER 656
            G                               ++ L P  QA  P       GQ   + +
Sbjct: 1136 GYTFPPAAATTTSTTTATATTTAVPAPTPAPQRLILSPDMQARLPSGEVVSIGQLASLAQ 1195

Query: 657  RPSQGAAGSPSLE----------SGGGPAPPALG-PR-----------VGGQD---QKDS 691
            RP   A GS  L           +G      A+G PR            GGQ     + +
Sbjct: 1196 RPVANAGGSKPLTFQIQGNKLTLTGAQVRQLAVGQPRPLQRNVVHLVSAGGQHHLISQPA 1255

Query: 692  PVAIPMSSGDTEDPGVASGYVSSADLVFTPNSGASSVSLVPSLGLPSDQTPSLCPGLASG 751
             VA+  +   T  P   S   SS     TP++  +   L  SL L ++Q P   P + + 
Sbjct: 1256 HVALIQAVAPTPGPTPVSVLPSS-----TPSTTPAPTGL--SLPLAANQVP---PTMVNN 1305

Query: 752  PPGAPGPVKSG-FEGYVELPPIEGRSPRSPRNNPVPPEAKSPVLNPGERPADVSPT--SP 808
                   V+    +G   +PP+   +PR P +         P L PG  P     T  +P
Sbjct: 1306 TGVVKIVVRQAPRDGLTPVPPL-APAPRPPSSGLPAVLNPRPTLTPGRLPTPTLGTARAP 1364

Query: 809  QPEGLLV------LQQVGDYCFLPGLGPGPLSLRSK---PSS-PGPGPEIKNLDQAFQVK 858
             P   LV      +            G  PL++ S    PSS PGP      +  +  + 
Sbjct: 1365 MPTPTLVRPLLKLVHSPSPEVSASAPGAAPLTISSPLHVPSSLPGPASSPMPIPNSSPLA 1424

Query: 859  KPPGQAV 865
             P    V
Sbjct: 1425 SPVSSTV 1431



 Score = 31.6 bits (70), Expect = 3.5
 Identities = 42/175 (24%), Positives = 60/175 (34%), Gaps = 26/175 (14%)

Query: 717  LVFTPNSGASSVSLVPSLG--LPSDQTPSLCPGL-------ASGPPGAPGPVKSGFEGYV 767
            +V  P +    V + P  G  L +  TP   P +       ++ P G P    S   G V
Sbjct: 1011 VVNNPRAPLGPVPVRPPPGPELSAQPTPGPVPQVLPASLMVSASPAGPPLIPASRPPGPV 1070

Query: 768  ELPPIEGRSPRSPRNNPVPPEAKSPVLNPGERPADVSPTSPQPEGLLVLQQVGDYCFL-- 825
             LPP++  S   P+  P P    S    P      + PT P P  L      G    L  
Sbjct: 1071 LLPPLQPNSGSLPQVLPSPLGVLSGTSRPPTPTLSLKPTPPAPVRLSPAPPPGSSSLLKP 1130

Query: 826  ----PGLGPGPLSLRSKPS-----------SPGPGPEIKNLDQAFQVKKPPGQAV 865
                PG    P +  +  +           +P P P+   L    Q + P G+ V
Sbjct: 1131 LTVPPGYTFPPAAATTTSTTTATATTTAVPAPTPAPQRLILSPDMQARLPSGEVV 1185


>gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo
           sapiens]
          Length = 1124

 Score = 62.4 bits (150), Expect = 2e-09
 Identities = 113/414 (27%), Positives = 151/414 (36%), Gaps = 60/414 (14%)

Query: 493 ELWPPGSMSAFTSGSPPHQGPWGSRFPELEGVFPVGFGDSEVSPLTIEDPKHVCDPPSGP 552
           ++ PP   +A   G P    P  +  P      PV   D+  +PL          PPS P
Sbjct: 284 QVTPPRKDAAPALG-PLSSSPLATPSPSGTKARPVPPPDNAATPLP------ATLPPSPP 336

Query: 553 DTTPAASDLPT-EQPPSPQ--PGPPAASHTPEKQASSFDFNGPYLGPPHSRSLPDILGQP 609
             TP     P+   PPS Q  P PPA   TP  QA       P   PP  +++P I   P
Sbjct: 337 LATPLPLAPPSPSAPPSLQTLPSPPA---TPPSQAPPSMTTPPMQAPPSLQTIPPI-QVP 392

Query: 610 EPPQEGGSQKSPPP---GSLEYLCLPAGGQVQLVPLAQAMGPGQ---AVEVERRPSQGAA 663
                   Q  P P    SL+         +Q       M P Q   ++    RP+    
Sbjct: 393 HSLTSPSLQAPPSPLALSSLQATTSLGSPTLQATHSFLTMSPRQTQASLTSPSRPASTPP 452

Query: 664 GSPSLESG-GGPAPPALGPRVGGQDQKDSPVAIPMSSGDTEDPGVASGYVSSADLVFTPN 722
            SP L++    PA P L   +       SP   P+SS  T  P  A   ++S     +P 
Sbjct: 453 DSPPLQAPLSLPASPPLQTSL-------SPAVSPLSSPLTIHPLQALSSLAS----HSPQ 501

Query: 723 SGASSVSLVP-----SLGLPSDQTPS---LCPGLASGPPGAPGPVKSG----FEGYVELP 770
           +  SS+ + P     SL  PS QTP      P L + P  AP P+++        ++E P
Sbjct: 502 APLSSLIMPPLETQSSLAPPSLQTPPASLTTPPLENLPSLAPPPLQTASAPLTTPHLETP 561

Query: 771 PIEG----RSPRSPRNNPVPPEAKSPVLNP--------GERPADVSPTSPQPEGLLVLQQ 818
           P       ++P SP   P PPE  S +  P           P    P+ P         Q
Sbjct: 562 PCPAPCPLQAPPSPLTTP-PPETPSSIATPPPQAPPALASPPLQGLPSPPLSPLATPPPQ 620

Query: 819 VGDYCFLPGLGPGPLSLRSKPSSP--GPGPEIKNLDQAFQVKKPPGQAVPQVPV 870
                 LP L   P    S P SP   P P+  N   A  + + P    P  PV
Sbjct: 621 APPXLALPPLQAPPSPPASPPLSPLATPSPQAPNA-LAVHLLQAPFSPPPSPPV 673



 Score = 58.9 bits (141), Expect = 2e-08
 Identities = 96/372 (25%), Positives = 131/372 (35%), Gaps = 59/372 (15%)

Query: 496 PPGSMSAFTSGSPPHQGPWGSRFPELEGVFPVGFGDSEVSPLTIEDPKHVCDPPSGPDTT 555
           PP         SPP   P  +  P+      V    +  SP      +    PP+ P  +
Sbjct: 628 PPLQAPPSPPASPP-LSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVS 686

Query: 556 PAASD----------LPTEQPPSPQPGPP-AASHTPEKQASSFDFNGPYLGPPHSRSLPD 604
           P+A+            P + PPSP   PP + S TP  QA            P   + P 
Sbjct: 687 PSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQA------------PPPLAAPP 734

Query: 605 ILGQPEPPQEGGSQKS--PPPGSLEYLCLPAGGQVQLVPLAQAMGPGQAVEVERRPSQGA 662
           +   P PP       S  PPP     L  P    +Q+ P   A  P   +      +  A
Sbjct: 735 LQVPPSPPASPPMSPSATPPPRVPPLLAAP---PLQVPPSPPASLPMSPLAKPPPQAPPA 791

Query: 663 AGSPSLESGGGPAPPALGPRVGGQDQKDSPVAIPMSSGDTEDPGVASGYVSSADLVFTPN 722
             +P L++   P+PPA  P   GQ       ++PMS   T  P      V +A L+  P 
Sbjct: 792 LATPPLQA--LPSPPASFP---GQAPFSPSASLPMSPLATPPPQAPP--VLAAPLLQVPP 844

Query: 723 SGASSVSLVPSLGLPSDQTPSLCPGLASGPPGAPGPVKSGFEGYVELPPIEGRSPRSPRN 782
           S  +S +L      P+    +   G       APGP           PP   RSP S  +
Sbjct: 845 SPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGP-----------PPPPSRSPSSTLS 893

Query: 783 NP-VPPEAKSPVLNPGE-RPADVSP-----TSPQPEGLLVLQQVGDYCFLPGLGPG-PLS 834
            P +   + S    P E R  D  P      SP P+  L       +      GP  PL+
Sbjct: 894 GPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAW----SRGPAPPLA 949

Query: 835 LRSKPSSPGPGP 846
            R  P +P P P
Sbjct: 950 FRGAPGAPLPWP 961



 Score = 51.2 bits (121), Expect = 4e-06
 Identities = 93/388 (23%), Positives = 132/388 (34%), Gaps = 64/388 (16%)

Query: 555 TPAAS--DLPTEQPP-SPQPGPP-------------AASHTPEKQ------ASSFDFNGP 592
           TPAA    L T +PP SP+P PP             A    P  +       ++   + P
Sbjct: 16  TPAARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAP 75

Query: 593 YLGPPHSRSLPDILGQPEPPQEGGSQKSPP-----------PGSLEYLCLPA--GGQVQL 639
             GP  S           PP  G  +++PP           PG       P   G +   
Sbjct: 76  RAGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLR 135

Query: 640 VPLAQAMGPGQAVEVERRP--SQGAAGSPSLESGGGPAPP------ALGPRVGGQDQKDS 691
           +   + +  G+A E  +R   S GA    S  + G P+P       A G  VG      S
Sbjct: 136 ISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPS 195

Query: 692 PVAIPMSSGDTEDPGVASGYVSS--ADLVFTPNSGASSVSLVPSLGLPSDQTPSLCPG-- 747
               P + G  +    AS + ++  +       S    +    S  L S  TP   P   
Sbjct: 196 ARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARS 255

Query: 748 --LASGPPGAPG-PVKSGFEGYVELPPIEGRSPRSPRNNPVPPEAKSPVLNPGERPADVS 804
              A G P AP  P +   +G   L P +   PR      + P + SP+  P        
Sbjct: 256 GPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSGTKAR 315

Query: 805 PTSPQPEGLLVLQQVGDYCFLPGLGPGPLSLRSKPSSPGPGPEIKNLDQAFQVKKPPGQA 864
           P  P       L        LP   P    L   P SP   P ++ L        PP QA
Sbjct: 316 PVPPPDNAATPLPAT-----LPPSPPLATPLPLAPPSPSAPPSLQTLPS--PPATPPSQA 368

Query: 865 VPQV--PVIQLFKALKQQDYLSLPPWEV 890
            P +  P +Q   +L+     ++PP +V
Sbjct: 369 PPSMTTPPMQAPPSLQ-----TIPPIQV 391


>gi|41349482 proline-rich protein BstNI subfamily 1 isoform 1
           preproprotein [Homo sapiens]
          Length = 331

 Score = 62.4 bits (150), Expect = 2e-09
 Identities = 79/287 (27%), Positives = 101/287 (35%), Gaps = 23/287 (8%)

Query: 540 EDPKHVCDPPSGPDTTPAASDLPTEQPP---SPQPGPPAASHTPEKQASSFDFNGPYLGP 596
           E P  +   P GP  +P   + P   PP    PQ  PP   + P+         GP    
Sbjct: 27  ESPSLIAGNPQGP--SPQGGNKPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQG 84

Query: 597 PHSRSLPDILGQPE-PPQEGGSQKS---PPPGSLEYLCLPAGGQVQ-LVPLAQAMGPGQA 651
             SRS     G+P+ PP +GG+Q     PPPG  +      G + Q   P  +  GP   
Sbjct: 85  DKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNRPQGPPPPGKPQGPPPQ 144

Query: 652 VEVERRPSQ--GAAGSPSLESGGGPAPPALGPRVGGQDQKDSPVAIPMSSGDTEDPGVAS 709
            +  R P    G    P  + G  P  P   P   G+ Q   P       G    PG   
Sbjct: 145 GDKSRSPRSPPGKPQGPPPQGGNQPQGP---PPPPGKPQGPPPQGGKKPQG-PPPPGKPQ 200

Query: 710 GYVSSADLVFTPNSGASSVSLVPSLGLPSDQTPSLCPGLASGPP--GAPGPVKSGFEGYV 767
           G     D   +  S        P  G    Q P   PG   GPP  G   P      G  
Sbjct: 201 GPPPQGDKSRSSQSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKP 260

Query: 768 ELPPIEG----RSPRSPRNNPV-PPEAKSPVLNPGERPADVSPTSPQ 809
           + PP +G    +S RSP   P  PP+ +         PA  +P  PQ
Sbjct: 261 QGPPAQGGSKSQSARSPPGKPQGPPQQEGNNPQGPPPPAGGNPQQPQ 307



 Score = 55.8 bits (133), Expect = 2e-07
 Identities = 72/242 (29%), Positives = 84/242 (34%), Gaps = 15/242 (6%)

Query: 637 VQLVPLAQAMGPGQAVEVERRPSQGAAGSPSLESGGGPAPPALGPRVGGQDQKDSPVAIP 696
           V L+ L+ A    + V  E  PS   AG+P   S  G   P   P   G+ Q   P    
Sbjct: 8   VALLALSSAQNLNEDVSQEESPSL-IAGNPQGPSPQGGNKPQGPPPPPGKPQGPPPQGGN 66

Query: 697 MSSGDTEDPGVASGYVSSADLVFTPNSGASSVSLVPSLGLPSDQTPSLCPGLASGPP--G 754
              G    PG   G     D   +P S        P  G    Q P   PG   GPP  G
Sbjct: 67  KPQGPPP-PGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQG 125

Query: 755 APGPVKSGFEGYVELPPIEG---RSPRSPRNNPVPPEAKSPVLNPGERPADVSPTSPQPE 811
              P      G  + PP +G   RSPRSP   P  P  +      G  P    P  P P+
Sbjct: 126 GNRPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQ 185

Query: 812 GLLVLQ---QVGDYCFLPGLGPGPLSLRSKPSSP-GPGPEIKNLDQAFQVKKPPGQAVPQ 867
           G    Q     G     P  G    S +S P  P GP P+  N  Q      PP    PQ
Sbjct: 186 GGKKPQGPPPPGKPQGPPPQGDKSRSSQSPPGKPQGPPPQGGNQPQG----PPPPPGKPQ 241

Query: 868 VP 869
            P
Sbjct: 242 GP 243


>gi|89363017 alpha 2 type V collagen preproprotein [Homo sapiens]
          Length = 1499

 Score = 62.0 bits (149), Expect = 2e-09
 Identities = 95/370 (25%), Positives = 118/370 (31%), Gaps = 56/370 (15%)

Query: 505  SGSPPHQGPWGSR-FPELEGVFPV--------GFGDSEVSPLTIEDPKHVCDPPSGPDTT 555
            SG+P   GP G +  P   G+           G G+         D       P GP   
Sbjct: 749  SGTPGDTGPPGLQGMPGERGIAGTPGPKGDRGGIGEKGAEGTAGNDGARGLPGPLGPPGP 808

Query: 556  PAASDLPTEQPPSPQPGPPAASHTPEKQASSFDFNGP-----YLGPPHSRSLPDILGQPE 610
               +    E  P    GPP +   P  +      NGP     + GP      P + G+P 
Sbjct: 809  AGPTGEKGEPGPRGLVGPPGSRGNPGSRGE----NGPTGAVGFAGPQGPDGQPGVKGEPG 864

Query: 611  PPQEGGSQKSPPPGSLEYLCLP---------AGGQVQLVPLAQAMGPGQAVEVERRPSQG 661
             P + G   SP P  L     P          GG+    P      PG A  V      G
Sbjct: 865  EPGQKGDAGSPGPQGLAGSPGPHGPNGVPGLKGGRGTQGPPGATGFPGSAGRVGPPGPAG 924

Query: 662  AAG-SPSLESGGGPAPPAL--GPRVGGQDQKDSPVAIPMSSGDTEDPGVASGYVSSADLV 718
            A G +  L   G   PP L   P   G+     P   P   GD  DPG            
Sbjct: 925  APGPAGPLGEPGKEGPPGLRGDPGSHGRVGDRGPAGPPGGPGDKGDPGEDGQPGPDG--- 981

Query: 719  FTPNSGASSVSLVPSLGLPSDQTPSLCPGLASGPPGAPGPVKSGFEGYVELPPIEGRSPR 778
              P   A +      +G+P  +     PGL  GP G PG V           P      +
Sbjct: 982  --PPGPAGTTGQRGIVGMPGQRGERGMPGL-PGPAGTPGKV----------GPTGATGDK 1028

Query: 779  SPRNNPVPPEAKSPVLNPG-ERPADVSPTSPQPEGLLVLQQVGDYCFLPGLGPGPLSLRS 837
             P     PP +  PV  PG E PA    T  +   +      GD        PGP  L  
Sbjct: 1029 GPPGPVGPPGSNGPVGEPGPEGPAGNDGTPGRDGAVGERGDRGD--------PGPAGLPG 1080

Query: 838  KPSSPG-PGP 846
               +PG PGP
Sbjct: 1081 SQGAPGTPGP 1090



 Score = 56.2 bits (134), Expect = 1e-07
 Identities = 102/417 (24%), Positives = 139/417 (33%), Gaps = 60/417 (14%)

Query: 506 GSPPHQGPWGSRFP---------ELEGV-FPVGFGDSEVSPLTIEDPKHV---------C 546
           G P H GP G   P         E  G+   VG     V P+    P+ +          
Sbjct: 177 GHPSHPGPDGLSRPFSAQMAGLDEKSGLGSQVGLMPGSVGPVGPRGPQGLQGQQGGAGPT 236

Query: 547 DPPSGPDTTPAASDLPTEQPPSPQPGPPAASHTPEKQASSFDFNGPYLGPPHSRSLPDIL 606
            PP  P        + +  P  P PG P     P +  +  +    + G P +R  P   
Sbjct: 237 GPPGEPGDPGPMGPIGSRGPEGP-PGKPGEDGEPGRNGNPGEVG--FAGSPGARGFPGAP 293

Query: 607 GQP-------EPPQEGGSQKSPPPGSLEYLCLPAGGQVQLVPLAQAMGPGQAVEVERRPS 659
           G P           EG   +   PGS +    P G    + PL     PG+   +  + +
Sbjct: 294 GLPGLKGHRGHKGLEGPKGEVGAPGS-KGEAGPTGPMGAMGPLGPRGMPGERGRLGPQGA 352

Query: 660 QGAAGSPSLESGGGPAPPALGPRVGGQDQKDSPV--AIPMSSGDTEDPGVASGYVSSADL 717
            G  G+  +    GP  P   P   G          A P  +   E P    G       
Sbjct: 353 PGQRGAHGMPGKPGPMGPLGIPGSSGFPGNPGMKGEAGPTGARGPEGPQGQRGETGPPGP 412

Query: 718 VFTPN-SGASSVSLVPSLGLPSDQTPSLCPGLASGPPGAPGPVKS----GFEGYVELPPI 772
           V +P   GA      P    P+    +  P  ++GPPG+PGP  S    G  G    P +
Sbjct: 413 VGSPGLPGAIGTDGTPGAKGPTGSPGTSGPPGSAGPPGSPGPQGSTGPQGIRGQPGDPGV 472

Query: 773 EG-RSPRSPRNNPVPPEAKSPVLNPGER--------PADVSPTSPQPE-GLLVLQQVGDY 822
            G +    P+  P P   + P+  PGE         P  V P  P  E G    +     
Sbjct: 473 PGFKGEAGPKGEPGPHGIQGPIGPPGEEGKRGPRGDPGTVGPPGPVGERGAPGNRGFPGS 532

Query: 823 CFLPG-------LGP----GPLSLRSKPSSPG-PG-PEIKNLDQAFQVKKPPGQAVP 866
             LPG        GP    GP   +  P  PG PG P  + L     V+ P G+  P
Sbjct: 533 DGLPGPKGAQGERGPVGSSGPKGSQGDPGRPGEPGLPGARGLTGNPGVQGPEGKLGP 589



 Score = 55.1 bits (131), Expect = 3e-07
 Identities = 106/387 (27%), Positives = 126/387 (32%), Gaps = 73/387 (18%)

Query: 497 PGSMSAFTS--GSPPHQGPWGSRFPELEGVFPVGFGDSEVSPLTIEDPKHVCDPPSGPDT 554
           PGS S F    G     GP G+R PE     P G       P  +  P        G D 
Sbjct: 374 PGS-SGFPGNPGMKGEAGPTGARGPE----GPQGQRGETGPPGPVGSPG--LPGAIGTDG 426

Query: 555 TPAASDLPTEQP-PSPQPGPPAASHTPEKQASSFDFNGPYLGPPHSRSLPDILGQPEPPQ 613
           TP A   PT  P  S  PG      +P  Q S+        GP   R  P   G P    
Sbjct: 427 TPGAKG-PTGSPGTSGPPGSAGPPGSPGPQGST--------GPQGIRGQPGDPGVPGFKG 477

Query: 614 EGGSQKSPPPGSLEYLCLPAGGQVQLVPLAQAMGPGQAVEVERRPSQGAAGSPSLESGGG 673
           E G +  P P  ++    P G + +  P       G    V  R + G  G P   S G 
Sbjct: 478 EAGPKGEPGPHGIQGPIGPPGEEGKRGPRGDPGTVGPPGPVGERGAPGNRGFPG--SDGL 535

Query: 674 PAPPALGPRVGGQDQKDSPVAIPMSSGDTEDPGVAS--GYVSSADLVFTPNSGASSVSLV 731
           P P       G Q ++  PV      G   DPG     G   +  L   P        L 
Sbjct: 536 PGPK------GAQGER-GPVGSSGPKGSQGDPGRPGEPGLPGARGLTGNPGVQGPEGKLG 588

Query: 732 PSLGLPSDQTPSLCPGLASGPPGAPGPVK-SGFEGYVELPPIEGRSPRSPRNNPVPPEAK 790
           P LG P +           G PG PG +   G  G + LP      P+    +P  P   
Sbjct: 589 P-LGAPGED----------GRPGPPGSIGIRGQPGSMGLP-----GPKGSSGDPGKPGEA 632

Query: 791 SPVLNPGERPADVSPTSPQPEGLLVLQQVGDYCFLPGLG--------PGPLSLRSKPSSP 842
                PG+R A        P G      VG     PGL         PGP   +  P  P
Sbjct: 633 GNAGVPGQRGAPGKDGEVGPSG-----PVGP----PGLAGERGEQGPPGPTGFQGLPGPP 683

Query: 843 GPGPEIKNLDQAFQVKKPPGQAVPQVP 869
           GP  E           KP  Q VP  P
Sbjct: 684 GPPGE---------GGKPGDQGVPGDP 701



 Score = 54.7 bits (130), Expect = 4e-07
 Identities = 78/294 (26%), Positives = 96/294 (32%), Gaps = 30/294 (10%)

Query: 569 PQPGPPAASHTPEKQASSFDFNGPYLGPPHSRSLPDILGQPEPPQEGGSQKSPPPGSLEY 628
           P P  P  S  P  +       GP  GP      P + GQP  P   G    P P  L  
Sbjct: 131 PGPAGPPGSQGPRGERGPKGRPGPR-GPQGIDGEPGVPGQPGAPGPPGHPSHPGPDGLSR 189

Query: 629 LCLPAGGQVQLVPLAQAMG------PGQAVEVERRPSQGAAGSPSLESGGGPAPPALGPR 682
              P   Q+  +     +G      PG    V  R  QG  G        GP      P 
Sbjct: 190 ---PFSAQMAGLDEKSGLGSQVGLMPGSVGPVGPRGPQGLQGQQGGAGPTGPPGEPGDPG 246

Query: 683 VGGQDQKDSPVAIPMSSGDTEDPGVASGYVSSADLVFTPNSGASSVSLVPSLGLPSDQTP 742
             G      P   P   G+  +PG      +  ++ F  + GA      P  GLP  +  
Sbjct: 247 PMGPIGSRGPEGPPGKPGEDGEPGRNG---NPGEVGFAGSPGARGFPGAP--GLPGLKGH 301

Query: 743 SLCPGLASGPPGAPG-PVKSGFEGYVELPPIEGRSPRSPRNNPVPPEAKSPVLNPGERPA 801
               GL  GP G  G P   G  G     P+    P  PR  P       P   PG+R A
Sbjct: 302 RGHKGL-EGPKGEVGAPGSKGEAG--PTGPMGAMGPLGPRGMPGERGRLGPQGAPGQRGA 358

Query: 802 DVSPTSPQPEGLLVLQQVGDYCFLPGL----GP-------GPLSLRSKPSSPGP 844
              P  P P G L +     +   PG+    GP       GP   R +   PGP
Sbjct: 359 HGMPGKPGPMGPLGIPGSSGFPGNPGMKGEAGPTGARGPEGPQGQRGETGPPGP 412



 Score = 43.9 bits (102), Expect = 7e-04
 Identities = 97/407 (23%), Positives = 132/407 (32%), Gaps = 86/407 (21%)

Query: 496 PPGSMSAFTSGSPPHQGPWGSRFPE----------LEGVFPVGFGDSEVSPLTIEDPKHV 545
           PPGS     +G P   GP GS  P+          + G         E  P  I+ P   
Sbjct: 442 PPGS-----AGPPGSPGPQGSTGPQGIRGQPGDPGVPGFKGEAGPKGEPGPHGIQGP--- 493

Query: 546 CDPPSGPDTTPAASDLPTEQPPSP--------QPGPPAASHTPEKQASSFDFNGPY--LG 595
             PP          D  T  PP P          G P +   P  + +  +  GP    G
Sbjct: 494 IGPPGEEGKRGPRGDPGTVGPPGPVGERGAPGNRGFPGSDGLPGPKGAQGE-RGPVGSSG 552

Query: 596 PPHSRSLPDILGQPEPPQEGGSQKSP----------------------PPGSLEYLCLPA 633
           P  S+  P   G+P  P   G   +P                      PPGS+     P 
Sbjct: 553 PKGSQGDPGRPGEPGLPGARGLTGNPGVQGPEGKLGPLGAPGEDGRPGPPGSIGIRGQP- 611

Query: 634 GGQVQLVPLAQAMGPGQAVEVERRPSQGAAGSPSLESGGGPAPPALGPRVGGQDQKD--- 690
           G      P   +  PG+  E       G  G+P  +   GP+ P   P + G+  +    
Sbjct: 612 GSMGLPGPKGSSGDPGKPGEAGNAGVPGQRGAPGKDGEVGPSGPVGPPGLAGERGEQGPP 671

Query: 691 ---------SPVAIPMSSGDTEDPGVASGYVSSADLVFTPNSGASSVSLVPSL-GLPSDQ 740
                     P   P   G   D GV     +   L      G       P + GLP ++
Sbjct: 672 GPTGFQGLPGPPGPPGEGGKPGDQGVPGDPGAVGPLGPRGERGNPGERGEPGITGLPGEK 731

Query: 741 TPSLCPGLASGPPGAPGPVKSGFEGYVELPPIEGR-SPRSPRNNPVPPEAKSPVLNPGER 799
             +   G   GP G+PGP  SG  G    P ++G    R     P P   +  +   GE+
Sbjct: 732 GMAGGHG-PDGPKGSPGP--SGTPGDTGPPGLQGMPGERGIAGTPGPKGDRGGI---GEK 785

Query: 800 PADVSPTSPQPEGLLVLQQVGDYCFLPG-LG-PGPLSLRSKPSSPGP 844
            A+ +  +    G            LPG LG PGP     +   PGP
Sbjct: 786 GAEGTAGNDGARG------------LPGPLGPPGPAGPTGEKGEPGP 820



 Score = 43.9 bits (102), Expect = 7e-04
 Identities = 96/386 (24%), Positives = 113/386 (29%), Gaps = 98/386 (25%)

Query: 487  FQNGSAELWPPGSMSAFTSGSPPHQGPWGSRFPELEGVFPVGFGDSEVSPLTIEDPKHVC 546
            F   +  + PPG      +G+P   GP G   P  EG  P G      S   + D     
Sbjct: 910  FPGSAGRVGPPGP-----AGAPGPAGPLGE--PGKEG--PPGLRGDPGSHGRVGDRG--- 957

Query: 547  DPPSGPDTTPAASDLPTEQPPSPQPGPPAASHTPEKQASSFDFNGPYLGPPHSRSLPDIL 606
              P+GP   P     P E       GPP                    GP  +     I+
Sbjct: 958  --PAGPPGGPGDKGDPGEDGQPGPDGPP--------------------GPAGTTGQRGIV 995

Query: 607  GQPEPPQEGGSQKSPPPGSLEYLCLPAGGQVQLVPLAQAMGPGQAVEVERRPSQGAAGSP 666
            G P    E G    P P        P G      P      PG    V     +G AG+ 
Sbjct: 996  GMPGQRGERGMPGLPGPAGTPGKVGPTGATGDKGPPGPVGPPGSNGPVGEPGPEGPAGND 1055

Query: 667  SL--------ESG--GGPAPPALGPRVGGQDQKDSPVAIPMSSGDTEDPGVASGYVSSAD 716
                      E G  G P P  L P   G      PV  P  +G   DPG       S  
Sbjct: 1056 GTPGRDGAVGERGDRGDPGPAGL-PGSQGAPGTPGPVGAPGDAGQRGDPG-------SRG 1107

Query: 717  LVFTPNSGASSVSLVPSLGLPSDQTPSLCPG-----------------LASGPPGAPGPV 759
             +  P             GLP  Q P    G                    G PG PGP 
Sbjct: 1108 PIGPPGRAGKR-------GLPGPQGPRGDKGDHGDRGDRGQKGHRGFTGLQGLPGPPGP- 1159

Query: 760  KSGFEGYVELPPIEGRSPRSPRNNPVPPEAKSPVLNPGERPADVSPTSPQPEGLLVLQQV 819
             +G +G   +P      P  PR  P P        NPG     + P  P      V   V
Sbjct: 1160 -NGEQGSAGIP-----GPFGPRGPPGPVGPSGKEGNPG----PLGPIGPPG----VRGSV 1205

Query: 820  GDYCFLPGLGP-GPLSLRSKPSSPGP 844
            G+       GP GP      P  PGP
Sbjct: 1206 GE------AGPEGPPGEPGPPGPPGP 1225



 Score = 35.4 bits (80), Expect = 0.24
 Identities = 59/225 (26%), Positives = 75/225 (33%), Gaps = 30/225 (13%)

Query: 684 GGQDQKDSPVAIPMSSGDTEDPGVASGYVSSADLVFTPNSGASSVSLVPSLGLPSDQTPS 743
           G + QK  P  +P+ +G    PG A            P S        P  G P  + P 
Sbjct: 110 GRKGQKGEPGLVPVVTGIRGRPGPAG----------PPGSQGPRGERGPK-GRPGPRGPQ 158

Query: 744 LCPGLAS--GPPGAPGPVKSGFEGYVELPPIEGRSPRSPRNNPVPPEAKSPVLNPGERPA 801
              G     G PGAPGP      G+   P  +G S           E        G  P 
Sbjct: 159 GIDGEPGVPGQPGAPGP-----PGHPSHPGPDGLSRPFSAQMAGLDEKSGLGSQVGLMPG 213

Query: 802 DVSPTSPQ-PEGLLVLQQVGDYCFLPGL----GP-GPLSLRSKPSSPG-PGPEIK----- 849
            V P  P+ P+GL   Q        PG     GP GP+  R     PG PG + +     
Sbjct: 214 SVGPVGPRGPQGLQGQQGGAGPTGPPGEPGDPGPMGPIGSRGPEGPPGKPGEDGEPGRNG 273

Query: 850 NLDQAFQVKKPPGQAVPQVPVIQLFKALKQQDYLSLPPWEVNKPG 894
           N  +      P  +  P  P +   K  +    L  P  EV  PG
Sbjct: 274 NPGEVGFAGSPGARGFPGAPGLPGLKGHRGHKGLEGPKGEVGAPG 318


>gi|239754955 PREDICTED: similar to COL22A1 protein [Homo sapiens]
          Length = 1073

 Score = 61.6 bits (148), Expect = 3e-09
 Identities = 106/373 (28%), Positives = 131/373 (35%), Gaps = 77/373 (20%)

Query: 496 PPGSMSAFTSGSPPHQGPWGSR----FPELEGVFPVGFGDSEVSPLTIED-PKHVC-DPP 549
           PPG      SG P  +G  GSR    FP  +G        S +SP  I    K VC D P
Sbjct: 511 PPGP-----SGPPGDKGSPGSRGLPGFPGPQGPAGRDGLSSLLSPGDINLLAKDVCNDCP 565

Query: 550 SGPDTTPAASDLPTEQPPSPQPGPPAASHTPEKQASSFDFNGPYLGPPHSRSLPDILGQP 609
            GP   P    LP  +     PG P    T  K+  +        GPP     P I G  
Sbjct: 566 PGP---PGLPGLPGFKGDKGVPGKPGREGTEGKKGEA--------GPPGLPGPPGIAGPQ 614

Query: 610 EPPQEGGS-----QKSPP--PGSLEYLCLPAG-GQVQLVPLAQAMGPGQAVEVERRPSQG 661
               E G+     QK     PG   ++  P   G      +A A GP            G
Sbjct: 615 GSQGERGADGEVGQKGDQGHPGVPGFMGPPGNPGPPGADGIAGAAGP-----------PG 663

Query: 662 AAGSPSLESGGGPAPPALGPRVGGQDQKDSPVAIPMSSGDTEDPGVASGYVSSADLVFTP 721
             GSP  E   GP  P+  P + G++ K+     P   G   +PG A             
Sbjct: 664 IQGSPGKEGPPGPQGPSGLPGIPGEEGKEGRDGKP---GPPGEPGKAG------------ 708

Query: 722 NSGASSVSLVPSLGLPSDQTPSLCPGLA--SGPPGAPGPVKSGFEGYVELPPIEGRSPRS 779
                        GLP  +     PG    +G  GAPGP   G  G + LP  EG   + 
Sbjct: 709 -----------EPGLPGPEGARGPPGFKGHTGDSGAPGP--RGESGAMGLPGQEGLPGKD 755

Query: 780 PRNNPVPPEA-KSPVLNPGERPADVSPTSPQPEGLLVLQQVGDYCFLPGLGPGPLSLRSK 838
               P  P+  + P   PG+  +  SP  P P G    +        PGL PG L  R  
Sbjct: 756 GDTGPTGPQGPQGPRGPPGKNGSPGSPGEPGPSGTPGQKGSKGENGSPGL-PGFLGPRGP 814

Query: 839 PSSPG----PGPE 847
           P  PG    PG E
Sbjct: 815 PGEPGEKGVPGKE 827



 Score = 49.3 bits (116), Expect = 2e-05
 Identities = 78/294 (26%), Positives = 99/294 (33%), Gaps = 48/294 (16%)

Query: 496 PPGSMS-AFTSGSPPHQGPWGSRFPELEGVFPVGFGDSEVSPLTIEDPKHVCDPPSGPDT 554
           PPG+   A  +G P  QG  G   P      P   G S +  +  E+ K   D   GP  
Sbjct: 649 PPGADGIAGAAGPPGIQGSPGKEGP------PGPQGPSGLPGIPGEEGKEGRDGKPGPPG 702

Query: 555 TPAASDLPTEQPPSPQPGPPA-ASHTPEKQASSFDFNGPYLGPPHSRSLPDILGQPEPPQ 613
            P  +  P    P    GPP    HT +  A         +G P    LP   G   P  
Sbjct: 703 EPGKAGEPGLPGPEGARGPPGFKGHTGDSGAPGPRGESGAMGLPGQEGLPGKDGDTGPTG 762

Query: 614 EGGSQ-KSPPPGSLEYLCLPAGGQVQLVPLAQAMGPGQAVEVERRPSQGAAGSPSLESGG 672
             G Q    PPG       P               PG +    ++ S+G  GSP L    
Sbjct: 763 PQGPQGPRGPPGKNGSPGSPGE-------------PGPSGTPGQKGSKGENGSPGLPGFL 809

Query: 673 GPAPPALGP---RVGGQDQKDSPVAIPMSSGDTEDPGV------ASGYVSSADLVFTPNS 723
           GP  P   P    V G++        P   G+  DPG+        G     D     + 
Sbjct: 810 GPRGPPGEPGEKGVPGKEGVPGKPGEPGFKGERGDPGIKGDKGPPGGKGQPGDPGIPGHK 869

Query: 724 GASSVSLVPSLGLPSDQTPSLCPGLASGPPGAPGPVKSGFEGYVELPPIEGRSP 777
           G     L+   GLP +  P        GPPG PG  + GF      P + G SP
Sbjct: 870 G--HTGLMGPQGLPGENGP-------VGPPGPPG--QPGF------PGLRGESP 906



 Score = 40.0 bits (92), Expect = 0.010
 Identities = 56/241 (23%), Positives = 77/241 (31%), Gaps = 33/241 (13%)

Query: 549  PSGPDTTPAASDLPTEQPPSPQPGPPAASHTPEKQASSFDFNGP---------------- 592
            P GP   P    +P ++    +PG P             D   P                
Sbjct: 811  PRGPPGEPGEKGVPGKEGVPGKPGEPGFKGERGDPGIKGDKGPPGGKGQPGDPGIPGHKG 870

Query: 593  ---YLGPPHSRSLPDILGQPEPPQEGGSQ----KSPPPGSLEYLCLPAGG---QVQLVPL 642
                +GP         +G P PP + G      +SP   +L  L     G   + +L  L
Sbjct: 871  HTGLMGPQGLPGENGPVGPPGPPGQPGFPGLRGESPSMETLRRLIQEELGKQLETRLAYL 930

Query: 643  AQAMGPGQAVEVERRPSQ-GAAGSPSLESGGGPAPPALGPRVGGQDQKDSPVAIPMSSGD 701
               M P      + RP   G  G   L    GP      P  GG +    P+      G 
Sbjct: 931  LAQMPPAYMKSSQGRPGPPGPPGKDGLPGRAGPMGEPGRPGQGGLEGPSGPIGPKGERGA 990

Query: 702  TEDPGVAS----GYVSSADLVFTPNSGASSVSLVPSLGLPSDQT-PSLCPGLASGPPGAP 756
              DPG       G +    +   P     +   +P +  P  +T P+  PGL  GPPG P
Sbjct: 991  KGDPGAPGVGLRGEMGPPGIPGQPGEPGYAKDGLPGIPGPQGETGPAGHPGL-PGPPGPP 1049

Query: 757  G 757
            G
Sbjct: 1050 G 1050



 Score = 34.3 bits (77), Expect = 0.53
 Identities = 60/221 (27%), Positives = 74/221 (33%), Gaps = 51/221 (23%)

Query: 648 PGQAVEVERRPSQGAAGSPSLESGGG---PAPPALGPRVGGQD-QKDSPVAI--PMSSGD 701
           PG+      +   G  G P L+   G   P  P   P   GQ+    +P A   P + G 
Sbjct: 346 PGEQGPKGEKGDPGLPGEPGLQGRPGELGPQGPTGPPGAKGQEGAHGAPGAAGNPGAPGH 405

Query: 702 TEDPGVAS--GYVSSADLVFTPNSGAS--SVSLVPSLGLPSDQTPSLCPGLASGPPGAPG 757
              PG +   G V +  L  TP               G P    P   PG     PG PG
Sbjct: 406 VGAPGPSGPPGSVGAPGLRGTPGKDGERGEKGAAGEEGSPGPVGPRGDPGA----PGLPG 461

Query: 758 PVKSGFEGYVELPPIEGRSPRSPRNNPVPPEAKSPVLNPGERPADVSPTSPQPEGLLVLQ 817
           P   G +G    P + G SP  P           P+   G+R A   P SP   G     
Sbjct: 462 PPGKGKDGE---PGLRG-SPGLP----------GPLGTKGDRGAPGIPGSPGSRG----- 502

Query: 818 QVGDYCFLPGLG----PGPLSLRSKPSSPG-------PGPE 847
                   PG+G    PGP        SPG       PGP+
Sbjct: 503 -------DPGIGVAGPPGPSGPPGDKGSPGSRGLPGFPGPQ 536


>gi|111118972 collagen, type XI, alpha 2 isoform 2 preproprotein [Homo
            sapiens]
          Length = 1650

 Score = 61.2 bits (147), Expect = 4e-09
 Identities = 92/340 (27%), Positives = 113/340 (33%), Gaps = 41/340 (12%)

Query: 551  GPDTTPAASDLPTEQPPSPQPGPPAASHTPEK--------QASSFDFNGPY--LGPPHSR 600
            GP   P    LP  Q P+  PGP      P K        Q     F G     GPP   
Sbjct: 782  GPHGPPGERGLPGPQGPNGFPGPKGPPGPPGKDGLPGHPGQRGEVGFQGKTGPPGPPGVV 841

Query: 601  SLPDILGQPEPPQEGGSQKSPPPGSLEYLCLPAGGQVQLVPLAQAMGPGQAVEVERR--P 658
                  G+  P  E G    P P   + L   AG +           PG+      R  P
Sbjct: 842  GPQGAAGETGPMGERGHPGPPGPPGEQGLPGTAGKEGTKGDPGPPGAPGKDGPAGLRGFP 901

Query: 659  SQ----GAAGSPSL---ESGGGPAPPALGPRVGGQDQKDSPVAIPMSSGDTEDPGVASGY 711
             +    G AG P L   E   GP  PA  P   G      P+  P   G    PG A   
Sbjct: 902  GERGLPGTAGGPGLKGNEGPSGPPGPAGSPGERGAAGSGGPIGPPGRPGPQGPPGAAG-- 959

Query: 712  VSSADLVFTPNSGASSVSLVPSLGLPSDQTPSLCPGLASGPPGAPGPVKSGFEGYVELPP 771
                               +   G    Q P   PG A GPPG  G  + G +G V  P 
Sbjct: 960  ---------EKGVPGEKGPIGPTGRDGVQGPVGLPGPA-GPPGVAG--EDGDKGEVGDPG 1007

Query: 772  IEG-RSPRSPRNNPVPPEAKSPVLNPGERPADVSPTSPQPEGLLVLQQVGDYCFLPGLG- 829
             +G +  +     P PP    PV  PG   AD  P +  P+G    +  GD       G 
Sbjct: 1008 QKGTKGNKGEHGPPGPPGPIGPVGQPGAAGADGEPGARGPQGHFGAK--GDEGTRGFNGP 1065

Query: 830  PGPLSLRSKPSSPGPGPEIKNLDQAFQVKKPPGQAVPQVP 869
            PGP+ L+  P   G   E  ++        PPG   P+ P
Sbjct: 1066 PGPIGLQGLPGPSGEKGETGDVGP----MGPPGPPGPRGP 1101



 Score = 45.4 bits (106), Expect = 2e-04
 Identities = 84/319 (26%), Positives = 104/319 (32%), Gaps = 61/319 (19%)

Query: 564 EQPPSPQPGPPAASHTPEKQASSFDFNGP-YLGPPHSRSLPDILGQPEPPQ--------- 613
           E PP P+ GP      P  Q +      P   GPP    LP   G P PP          
Sbjct: 312 EGPPGPE-GPAGLIGPPGIQGNPGPVGDPGERGPPGRAGLPGSDGAPGPPGTSLMLPFRF 370

Query: 614 -EGGSQKSPPPGSLEYLCLPAGGQVQLVPLAQAMGPGQAVEVERRPSQGAAGSPSLESGG 672
             GG  K P   + E     A   +Q   LA    PG      R    G  GSP L+   
Sbjct: 371 GSGGGDKGPVVAAQE---AQAQAILQQARLALRGPPGPMGYTGRPGPLGQPGSPGLKGES 427

Query: 673 GPAPPALGPRVGGQDQKDSP--------VAIPMSSGDTEDPGVAS--GYVSSADLV---- 718
           G   P  GPR G Q     P             + G   DPGV    G+     L     
Sbjct: 428 GDLGPQ-GPR-GPQGLTGPPGKAGRRGRAGADGARGMPGDPGVKGDRGFDGLPGLPGEKG 485

Query: 719 FTPNSGASSVSLVPS-------------LGLPSDQTPSLCPGLASGPPGAPGPVKSGFEG 765
              ++GA  +   P               GLP +  P    G   GPPG PGP       
Sbjct: 486 HRGDTGAQGLPGPPGEDGERGDDGEIGPRGLPGESGPRGLLG-PKGPPGIPGP------- 537

Query: 766 YVELPPIEGR-SPRSPRNNPVPPEAKSPVLNPGERPADVSPTSPQPEGLLVLQQVGDYCF 824
               P + G   P+ P+ +  P     P   PG++    +   P P+G +          
Sbjct: 538 ----PGVRGMDGPQGPKGSLGPQGEPGP---PGQQGTPGTQGLPGPQGAIGPHGEKGPQG 590

Query: 825 LPGLGPGPLSLRSKPSSPG 843
            PGL PG       P  PG
Sbjct: 591 KPGL-PGMPGSDGPPGHPG 608



 Score = 45.4 bits (106), Expect = 2e-04
 Identities = 86/366 (23%), Positives = 123/366 (33%), Gaps = 64/366 (17%)

Query: 564  EQPPSPQPGPPAASHTPEKQASSFDFNGPYLGPPHSRSLPDILGQPEPPQEGGSQ----- 618
            E+  S QPG P     P  +  + D +GP  G P     P   G P PP EGG +     
Sbjct: 1152 EKGESGQPGEPGP---PGPKGPTGD-DGPK-GNPGPVGFP---GDPGPPGEGGPRGQDGA 1203

Query: 619  --------KSPPPGSLEYLCLPAGGQVQLVPLAQAMGPGQAVEVERRPSQGAAGSPSLES 670
                    +   PGS      P G      PL +    G      R+  +GA G P    
Sbjct: 1204 KGDRGEDGEPGQPGSPG----PTGENGPPGPLGKRGPAGSPGSEGRQGGKGAKGDPGAIG 1259

Query: 671  GGGPAPPALGPRVGGQDQKDSPVAIPMSSGDTEDPGVASGYVSSADLVFTP-------NS 723
              G   P       G+   D    +P S G    PG A+G       V  P       ++
Sbjct: 1260 APGKTGPVGPAGPAGKPGPDGLRGLPGSVGQQGRPG-ATGQAGPPGPVGPPGLPGLRGDA 1318

Query: 724  GASS----VSLVPSLGLPSDQTPSLCPGLASGPPGAPGPVKSGFEGYVELPPIEGR-SPR 778
            GA        L+  +G P +Q      GL  GP G+PG      +G + +P   G   P 
Sbjct: 1319 GAKGEKGHPGLIGLIGPPGEQGEKGDRGL-PGPQGSPGQ-----KGEMGIPGASGPIGPG 1372

Query: 779  SPRNNPVP--PEAKSPVLNP----GERPADVSPTSPQPEGLLVLQQVGDYCFLPGLGPGP 832
             P   P P  P+       P    GE+     P  P P G ++              P P
Sbjct: 1373 GPPGLPGPAGPKGAKGATGPGGPKGEKGVQGPPGHPGPPGEVI-------------QPLP 1419

Query: 833  LSLRSKPSSPGPGPEIKNLDQAFQVKKPPGQAVPQVPVIQLFKALKQQ-DYLSLPPWEVN 891
            + +  K      G  +   D+A      PG       +     +L+++ + +  P    +
Sbjct: 1420 IQMPKKTRRSVDGSRLMQEDEAIPTGGAPGSPGGLEEIFGSLDSLREEIEQMRRPTGTQD 1479

Query: 892  KPGEVC 897
             P   C
Sbjct: 1480 SPARTC 1485



 Score = 38.9 bits (89), Expect = 0.022
 Identities = 97/402 (24%), Positives = 123/402 (30%), Gaps = 78/402 (19%)

Query: 496  PPGSMSAFTSGSPPHQGPWGSRFPE-LEGVFPVGF-GDSEVSPLTIED-PKHVCDPPSGP 552
            PPG+  A   G P  +GP G    + ++G  PVG  G +    +  ED  K     P   
Sbjct: 954  PPGA--AGEKGVPGEKGPIGPTGRDGVQG--PVGLPGPAGPPGVAGEDGDKGEVGDPGQK 1009

Query: 553  DTTPAASDLPTEQPPSP-----QPGPPAASHTPEKQA-----------SSFDFNGPYLGP 596
             T     +     PP P     QPG   A   P  +             +  FNGP  GP
Sbjct: 1010 GTKGNKGEHGPPGPPGPIGPVGQPGAAGADGEPGARGPQGHFGAKGDEGTRGFNGPP-GP 1068

Query: 597  PHSRSLPDILGQPEPPQEGGSQKSP-PPGSLEYLCLPAGGQVQLVPLAQAMGPGQAVEVE 655
               + LP   G+     + G    P PPG       PAG      P     G G      
Sbjct: 1069 IGLQGLPGPSGEKGETGDVGPMGPPGPPGPRG----PAGPNGADGPQGPPGGVGNLGPPG 1124

Query: 656  RRPSQGAAGSPSLESGGGPAPPALGPRVGGQDQKDSPVAIPMSSGDTEDPGVASGYVSSA 715
             +   G +GSP ++   G   P       G+  +      P   G T D G         
Sbjct: 1125 EKGEPGESGSPGIQGEPGVKGPRGERGEKGESGQPGEPGPPGPKGPTGDDG--------- 1175

Query: 716  DLVFTPNSGASSVSLVPSLGLPSDQTPSLCPGLAS--------GPPGAPGPV-KSGFEGY 766
                 P      V      G P +  P    G           G PG+PGP  ++G  G 
Sbjct: 1176 -----PKGNPGPVGFPGDPGPPGEGGPRGQDGAKGDRGEDGEPGQPGSPGPTGENGPPG- 1229

Query: 767  VELPPIEGRSPRSPRNNPVPPEAKSPVLNPGE--RPADVSPTSPQPEGLLVLQQVGDYCF 824
                P+  R P     +      K    +PG    P    P  P                
Sbjct: 1230 ----PLGKRGPAGSPGSEGRQGGKGAKGDPGAIGAPGKTGPVGPAG-------------- 1271

Query: 825  LPGLGPGPLSLRSKPSSPGPGPEIKNLDQAFQVKKPPGQAVP 866
             P   PGP  LR  P S G         QA     PPG   P
Sbjct: 1272 -PAGKPGPDGLRGLPGSVGQQGRPGATGQA----GPPGPVGP 1308


>gi|111118968 collagen, type XI, alpha 2 isoform 3 preproprotein [Homo
            sapiens]
          Length = 1629

 Score = 61.2 bits (147), Expect = 4e-09
 Identities = 92/340 (27%), Positives = 113/340 (33%), Gaps = 41/340 (12%)

Query: 551  GPDTTPAASDLPTEQPPSPQPGPPAASHTPEK--------QASSFDFNGPY--LGPPHSR 600
            GP   P    LP  Q P+  PGP      P K        Q     F G     GPP   
Sbjct: 761  GPHGPPGERGLPGPQGPNGFPGPKGPPGPPGKDGLPGHPGQRGEVGFQGKTGPPGPPGVV 820

Query: 601  SLPDILGQPEPPQEGGSQKSPPPGSLEYLCLPAGGQVQLVPLAQAMGPGQAVEVERR--P 658
                  G+  P  E G    P P   + L   AG +           PG+      R  P
Sbjct: 821  GPQGAAGETGPMGERGHPGPPGPPGEQGLPGTAGKEGTKGDPGPPGAPGKDGPAGLRGFP 880

Query: 659  SQ----GAAGSPSL---ESGGGPAPPALGPRVGGQDQKDSPVAIPMSSGDTEDPGVASGY 711
             +    G AG P L   E   GP  PA  P   G      P+  P   G    PG A   
Sbjct: 881  GERGLPGTAGGPGLKGNEGPSGPPGPAGSPGERGAAGSGGPIGPPGRPGPQGPPGAAG-- 938

Query: 712  VSSADLVFTPNSGASSVSLVPSLGLPSDQTPSLCPGLASGPPGAPGPVKSGFEGYVELPP 771
                               +   G    Q P   PG A GPPG  G  + G +G V  P 
Sbjct: 939  ---------EKGVPGEKGPIGPTGRDGVQGPVGLPGPA-GPPGVAG--EDGDKGEVGDPG 986

Query: 772  IEG-RSPRSPRNNPVPPEAKSPVLNPGERPADVSPTSPQPEGLLVLQQVGDYCFLPGLG- 829
             +G +  +     P PP    PV  PG   AD  P +  P+G    +  GD       G 
Sbjct: 987  QKGTKGNKGEHGPPGPPGPIGPVGQPGAAGADGEPGARGPQGHFGAK--GDEGTRGFNGP 1044

Query: 830  PGPLSLRSKPSSPGPGPEIKNLDQAFQVKKPPGQAVPQVP 869
            PGP+ L+  P   G   E  ++        PPG   P+ P
Sbjct: 1045 PGPIGLQGLPGPSGEKGETGDVGP----MGPPGPPGPRGP 1080



 Score = 45.4 bits (106), Expect = 2e-04
 Identities = 84/319 (26%), Positives = 104/319 (32%), Gaps = 61/319 (19%)

Query: 564 EQPPSPQPGPPAASHTPEKQASSFDFNGP-YLGPPHSRSLPDILGQPEPPQ--------- 613
           E PP P+ GP      P  Q +      P   GPP    LP   G P PP          
Sbjct: 291 EGPPGPE-GPAGLIGPPGIQGNPGPVGDPGERGPPGRAGLPGSDGAPGPPGTSLMLPFRF 349

Query: 614 -EGGSQKSPPPGSLEYLCLPAGGQVQLVPLAQAMGPGQAVEVERRPSQGAAGSPSLESGG 672
             GG  K P   + E     A   +Q   LA    PG      R    G  GSP L+   
Sbjct: 350 GSGGGDKGPVVAAQE---AQAQAILQQARLALRGPPGPMGYTGRPGPLGQPGSPGLKGES 406

Query: 673 GPAPPALGPRVGGQDQKDSP--------VAIPMSSGDTEDPGVAS--GYVSSADLV---- 718
           G   P  GPR G Q     P             + G   DPGV    G+     L     
Sbjct: 407 GDLGPQ-GPR-GPQGLTGPPGKAGRRGRAGADGARGMPGDPGVKGDRGFDGLPGLPGEKG 464

Query: 719 FTPNSGASSVSLVPS-------------LGLPSDQTPSLCPGLASGPPGAPGPVKSGFEG 765
              ++GA  +   P               GLP +  P    G   GPPG PGP       
Sbjct: 465 HRGDTGAQGLPGPPGEDGERGDDGEIGPRGLPGESGPRGLLG-PKGPPGIPGP------- 516

Query: 766 YVELPPIEGR-SPRSPRNNPVPPEAKSPVLNPGERPADVSPTSPQPEGLLVLQQVGDYCF 824
               P + G   P+ P+ +  P     P   PG++    +   P P+G +          
Sbjct: 517 ----PGVRGMDGPQGPKGSLGPQGEPGP---PGQQGTPGTQGLPGPQGAIGPHGEKGPQG 569

Query: 825 LPGLGPGPLSLRSKPSSPG 843
            PGL PG       P  PG
Sbjct: 570 KPGL-PGMPGSDGPPGHPG 587



 Score = 45.4 bits (106), Expect = 2e-04
 Identities = 86/366 (23%), Positives = 123/366 (33%), Gaps = 64/366 (17%)

Query: 564  EQPPSPQPGPPAASHTPEKQASSFDFNGPYLGPPHSRSLPDILGQPEPPQEGGSQ----- 618
            E+  S QPG P     P  +  + D +GP  G P     P   G P PP EGG +     
Sbjct: 1131 EKGESGQPGEPGP---PGPKGPTGD-DGPK-GNPGPVGFP---GDPGPPGEGGPRGQDGA 1182

Query: 619  --------KSPPPGSLEYLCLPAGGQVQLVPLAQAMGPGQAVEVERRPSQGAAGSPSLES 670
                    +   PGS      P G      PL +    G      R+  +GA G P    
Sbjct: 1183 KGDRGEDGEPGQPGSPG----PTGENGPPGPLGKRGPAGSPGSEGRQGGKGAKGDPGAIG 1238

Query: 671  GGGPAPPALGPRVGGQDQKDSPVAIPMSSGDTEDPGVASGYVSSADLVFTP-------NS 723
              G   P       G+   D    +P S G    PG A+G       V  P       ++
Sbjct: 1239 APGKTGPVGPAGPAGKPGPDGLRGLPGSVGQQGRPG-ATGQAGPPGPVGPPGLPGLRGDA 1297

Query: 724  GASS----VSLVPSLGLPSDQTPSLCPGLASGPPGAPGPVKSGFEGYVELPPIEGR-SPR 778
            GA        L+  +G P +Q      GL  GP G+PG      +G + +P   G   P 
Sbjct: 1298 GAKGEKGHPGLIGLIGPPGEQGEKGDRGL-PGPQGSPGQ-----KGEMGIPGASGPIGPG 1351

Query: 779  SPRNNPVP--PEAKSPVLNP----GERPADVSPTSPQPEGLLVLQQVGDYCFLPGLGPGP 832
             P   P P  P+       P    GE+     P  P P G ++              P P
Sbjct: 1352 GPPGLPGPAGPKGAKGATGPGGPKGEKGVQGPPGHPGPPGEVI-------------QPLP 1398

Query: 833  LSLRSKPSSPGPGPEIKNLDQAFQVKKPPGQAVPQVPVIQLFKALKQQ-DYLSLPPWEVN 891
            + +  K      G  +   D+A      PG       +     +L+++ + +  P    +
Sbjct: 1399 IQMPKKTRRSVDGSRLMQEDEAIPTGGAPGSPGGLEEIFGSLDSLREEIEQMRRPTGTQD 1458

Query: 892  KPGEVC 897
             P   C
Sbjct: 1459 SPARTC 1464



 Score = 38.9 bits (89), Expect = 0.022
 Identities = 97/402 (24%), Positives = 123/402 (30%), Gaps = 78/402 (19%)

Query: 496  PPGSMSAFTSGSPPHQGPWGSRFPE-LEGVFPVGF-GDSEVSPLTIED-PKHVCDPPSGP 552
            PPG+  A   G P  +GP G    + ++G  PVG  G +    +  ED  K     P   
Sbjct: 933  PPGA--AGEKGVPGEKGPIGPTGRDGVQG--PVGLPGPAGPPGVAGEDGDKGEVGDPGQK 988

Query: 553  DTTPAASDLPTEQPPSP-----QPGPPAASHTPEKQA-----------SSFDFNGPYLGP 596
             T     +     PP P     QPG   A   P  +             +  FNGP  GP
Sbjct: 989  GTKGNKGEHGPPGPPGPIGPVGQPGAAGADGEPGARGPQGHFGAKGDEGTRGFNGPP-GP 1047

Query: 597  PHSRSLPDILGQPEPPQEGGSQKSP-PPGSLEYLCLPAGGQVQLVPLAQAMGPGQAVEVE 655
               + LP   G+     + G    P PPG       PAG      P     G G      
Sbjct: 1048 IGLQGLPGPSGEKGETGDVGPMGPPGPPGPRG----PAGPNGADGPQGPPGGVGNLGPPG 1103

Query: 656  RRPSQGAAGSPSLESGGGPAPPALGPRVGGQDQKDSPVAIPMSSGDTEDPGVASGYVSSA 715
             +   G +GSP ++   G   P       G+  +      P   G T D G         
Sbjct: 1104 EKGEPGESGSPGIQGEPGVKGPRGERGEKGESGQPGEPGPPGPKGPTGDDG--------- 1154

Query: 716  DLVFTPNSGASSVSLVPSLGLPSDQTPSLCPGLAS--------GPPGAPGPV-KSGFEGY 766
                 P      V      G P +  P    G           G PG+PGP  ++G  G 
Sbjct: 1155 -----PKGNPGPVGFPGDPGPPGEGGPRGQDGAKGDRGEDGEPGQPGSPGPTGENGPPG- 1208

Query: 767  VELPPIEGRSPRSPRNNPVPPEAKSPVLNPGE--RPADVSPTSPQPEGLLVLQQVGDYCF 824
                P+  R P     +      K    +PG    P    P  P                
Sbjct: 1209 ----PLGKRGPAGSPGSEGRQGGKGAKGDPGAIGAPGKTGPVGPAG-------------- 1250

Query: 825  LPGLGPGPLSLRSKPSSPGPGPEIKNLDQAFQVKKPPGQAVP 866
             P   PGP  LR  P S G         QA     PPG   P
Sbjct: 1251 -PAGKPGPDGLRGLPGSVGQQGRPGATGQA----GPPGPVGP 1287


>gi|111118970 collagen, type XI, alpha 2 isoform 1 preproprotein [Homo
            sapiens]
          Length = 1736

 Score = 61.2 bits (147), Expect = 4e-09
 Identities = 92/340 (27%), Positives = 113/340 (33%), Gaps = 41/340 (12%)

Query: 551  GPDTTPAASDLPTEQPPSPQPGPPAASHTPEK--------QASSFDFNGPY--LGPPHSR 600
            GP   P    LP  Q P+  PGP      P K        Q     F G     GPP   
Sbjct: 868  GPHGPPGERGLPGPQGPNGFPGPKGPPGPPGKDGLPGHPGQRGEVGFQGKTGPPGPPGVV 927

Query: 601  SLPDILGQPEPPQEGGSQKSPPPGSLEYLCLPAGGQVQLVPLAQAMGPGQAVEVERR--P 658
                  G+  P  E G    P P   + L   AG +           PG+      R  P
Sbjct: 928  GPQGAAGETGPMGERGHPGPPGPPGEQGLPGTAGKEGTKGDPGPPGAPGKDGPAGLRGFP 987

Query: 659  SQ----GAAGSPSL---ESGGGPAPPALGPRVGGQDQKDSPVAIPMSSGDTEDPGVASGY 711
             +    G AG P L   E   GP  PA  P   G      P+  P   G    PG A   
Sbjct: 988  GERGLPGTAGGPGLKGNEGPSGPPGPAGSPGERGAAGSGGPIGPPGRPGPQGPPGAAG-- 1045

Query: 712  VSSADLVFTPNSGASSVSLVPSLGLPSDQTPSLCPGLASGPPGAPGPVKSGFEGYVELPP 771
                               +   G    Q P   PG A GPPG  G  + G +G V  P 
Sbjct: 1046 ---------EKGVPGEKGPIGPTGRDGVQGPVGLPGPA-GPPGVAG--EDGDKGEVGDPG 1093

Query: 772  IEG-RSPRSPRNNPVPPEAKSPVLNPGERPADVSPTSPQPEGLLVLQQVGDYCFLPGLG- 829
             +G +  +     P PP    PV  PG   AD  P +  P+G    +  GD       G 
Sbjct: 1094 QKGTKGNKGEHGPPGPPGPIGPVGQPGAAGADGEPGARGPQGHFGAK--GDEGTRGFNGP 1151

Query: 830  PGPLSLRSKPSSPGPGPEIKNLDQAFQVKKPPGQAVPQVP 869
            PGP+ L+  P   G   E  ++        PPG   P+ P
Sbjct: 1152 PGPIGLQGLPGPSGEKGETGDVGP----MGPPGPPGPRGP 1187



 Score = 49.7 bits (117), Expect = 1e-05
 Identities = 104/427 (24%), Positives = 137/427 (32%), Gaps = 89/427 (20%)

Query: 475 EEKIPNPSKSHLFQNGSAELWPPGSMSAFTS------GSPPHQGPWGSRFPELEGVFPVG 528
           EE+I   S     +    +L  P +   F +      G+ P +GP+          +  G
Sbjct: 299 EEEILESSLLPPLEEEQTDLQVPPTADRFQAEEYGEGGTDPPEGPYD---------YTYG 349

Query: 529 FGD-----SEVSPLTIEDPKHVCDPPSGPDTTPAASDLPT--------EQPPSPQPGPPA 575
           +GD     +E+ P    +  H      GP         P         E PP P+ GP  
Sbjct: 350 YGDDYREETELGPALSAETAHSGAAAHGPRGLKGEKGEPAVLEPGMLVEGPPGPE-GPAG 408

Query: 576 ASHTPEKQASSFDFNGP-YLGPPHSRSLPDILGQPEPPQ----------EGGSQKSPPPG 624
               P  Q +      P   GPP    LP   G P PP            GG  K P   
Sbjct: 409 LIGPPGIQGNPGPVGDPGERGPPGRAGLPGSDGAPGPPGTSLMLPFRFGSGGGDKGPVVA 468

Query: 625 SLEYLCLPAGGQVQLVPLAQAMGPGQAVEVERRPSQGAAGSPSLESGGGPAPPALGPRVG 684
           + E     A   +Q   LA    PG      R    G  GSP L+   G   P  GPR G
Sbjct: 469 AQE---AQAQAILQQARLALRGPPGPMGYTGRPGPLGQPGSPGLKGESGDLGPQ-GPR-G 523

Query: 685 GQDQKDSP--------VAIPMSSGDTEDPGVAS--GYVSSADLV----FTPNSGASSVSL 730
            Q     P             + G   DPGV    G+     L        ++GA  +  
Sbjct: 524 PQGLTGPPGKAGRRGRAGADGARGMPGDPGVKGDRGFDGLPGLPGEKGHRGDTGAQGLPG 583

Query: 731 VPS-------------LGLPSDQTPSLCPGLASGPPGAPGPVKSGFEGYVELPPIEGR-S 776
            P               GLP +  P    G   GPPG PGP           P + G   
Sbjct: 584 PPGEDGERGDDGEIGPRGLPGESGPRGLLG-PKGPPGIPGP-----------PGVRGMDG 631

Query: 777 PRSPRNNPVPPEAKSPVLNPGERPADVSPTSPQPEGLLVLQQVGDYCFLPGLGPGPLSLR 836
           P+ P+ +  P     P   PG++    +   P P+G +           PGL PG     
Sbjct: 632 PQGPKGSLGPQGEPGP---PGQQGTPGTQGLPGPQGAIGPHGEKGPQGKPGL-PGMPGSD 687

Query: 837 SKPSSPG 843
             P  PG
Sbjct: 688 GPPGHPG 694



 Score = 45.4 bits (106), Expect = 2e-04
 Identities = 86/366 (23%), Positives = 123/366 (33%), Gaps = 64/366 (17%)

Query: 564  EQPPSPQPGPPAASHTPEKQASSFDFNGPYLGPPHSRSLPDILGQPEPPQEGGSQ----- 618
            E+  S QPG P     P  +  + D +GP  G P     P   G P PP EGG +     
Sbjct: 1238 EKGESGQPGEPGP---PGPKGPTGD-DGPK-GNPGPVGFP---GDPGPPGEGGPRGQDGA 1289

Query: 619  --------KSPPPGSLEYLCLPAGGQVQLVPLAQAMGPGQAVEVERRPSQGAAGSPSLES 670
                    +   PGS      P G      PL +    G      R+  +GA G P    
Sbjct: 1290 KGDRGEDGEPGQPGSPG----PTGENGPPGPLGKRGPAGSPGSEGRQGGKGAKGDPGAIG 1345

Query: 671  GGGPAPPALGPRVGGQDQKDSPVAIPMSSGDTEDPGVASGYVSSADLVFTP-------NS 723
              G   P       G+   D    +P S G    PG A+G       V  P       ++
Sbjct: 1346 APGKTGPVGPAGPAGKPGPDGLRGLPGSVGQQGRPG-ATGQAGPPGPVGPPGLPGLRGDA 1404

Query: 724  GASS----VSLVPSLGLPSDQTPSLCPGLASGPPGAPGPVKSGFEGYVELPPIEGR-SPR 778
            GA        L+  +G P +Q      GL  GP G+PG      +G + +P   G   P 
Sbjct: 1405 GAKGEKGHPGLIGLIGPPGEQGEKGDRGL-PGPQGSPGQ-----KGEMGIPGASGPIGPG 1458

Query: 779  SPRNNPVP--PEAKSPVLNP----GERPADVSPTSPQPEGLLVLQQVGDYCFLPGLGPGP 832
             P   P P  P+       P    GE+     P  P P G ++              P P
Sbjct: 1459 GPPGLPGPAGPKGAKGATGPGGPKGEKGVQGPPGHPGPPGEVI-------------QPLP 1505

Query: 833  LSLRSKPSSPGPGPEIKNLDQAFQVKKPPGQAVPQVPVIQLFKALKQQ-DYLSLPPWEVN 891
            + +  K      G  +   D+A      PG       +     +L+++ + +  P    +
Sbjct: 1506 IQMPKKTRRSVDGSRLMQEDEAIPTGGAPGSPGGLEEIFGSLDSLREEIEQMRRPTGTQD 1565

Query: 892  KPGEVC 897
             P   C
Sbjct: 1566 SPARTC 1571



 Score = 38.9 bits (89), Expect = 0.022
 Identities = 97/402 (24%), Positives = 123/402 (30%), Gaps = 78/402 (19%)

Query: 496  PPGSMSAFTSGSPPHQGPWGSRFPE-LEGVFPVGF-GDSEVSPLTIED-PKHVCDPPSGP 552
            PPG+  A   G P  +GP G    + ++G  PVG  G +    +  ED  K     P   
Sbjct: 1040 PPGA--AGEKGVPGEKGPIGPTGRDGVQG--PVGLPGPAGPPGVAGEDGDKGEVGDPGQK 1095

Query: 553  DTTPAASDLPTEQPPSP-----QPGPPAASHTPEKQA-----------SSFDFNGPYLGP 596
             T     +     PP P     QPG   A   P  +             +  FNGP  GP
Sbjct: 1096 GTKGNKGEHGPPGPPGPIGPVGQPGAAGADGEPGARGPQGHFGAKGDEGTRGFNGPP-GP 1154

Query: 597  PHSRSLPDILGQPEPPQEGGSQKSP-PPGSLEYLCLPAGGQVQLVPLAQAMGPGQAVEVE 655
               + LP   G+     + G    P PPG       PAG      P     G G      
Sbjct: 1155 IGLQGLPGPSGEKGETGDVGPMGPPGPPGPRG----PAGPNGADGPQGPPGGVGNLGPPG 1210

Query: 656  RRPSQGAAGSPSLESGGGPAPPALGPRVGGQDQKDSPVAIPMSSGDTEDPGVASGYVSSA 715
             +   G +GSP ++   G   P       G+  +      P   G T D G         
Sbjct: 1211 EKGEPGESGSPGIQGEPGVKGPRGERGEKGESGQPGEPGPPGPKGPTGDDG--------- 1261

Query: 716  DLVFTPNSGASSVSLVPSLGLPSDQTPSLCPGLAS--------GPPGAPGPV-KSGFEGY 766
                 P      V      G P +  P    G           G PG+PGP  ++G  G 
Sbjct: 1262 -----PKGNPGPVGFPGDPGPPGEGGPRGQDGAKGDRGEDGEPGQPGSPGPTGENGPPG- 1315

Query: 767  VELPPIEGRSPRSPRNNPVPPEAKSPVLNPGE--RPADVSPTSPQPEGLLVLQQVGDYCF 824
                P+  R P     +      K    +PG    P    P  P                
Sbjct: 1316 ----PLGKRGPAGSPGSEGRQGGKGAKGDPGAIGAPGKTGPVGPAG-------------- 1357

Query: 825  LPGLGPGPLSLRSKPSSPGPGPEIKNLDQAFQVKKPPGQAVP 866
             P   PGP  LR  P S G         QA     PPG   P
Sbjct: 1358 -PAGKPGPDGLRGLPGSVGQQGRPGATGQA----GPPGPVGP 1394


>gi|32964830 collagen, type VIII, alpha 2 [Homo sapiens]
          Length = 703

 Score = 60.1 bits (144), Expect = 9e-09
 Identities = 100/337 (29%), Positives = 124/337 (36%), Gaps = 47/337 (13%)

Query: 489 NGSAELWPPGSMSAFTSGSPPH-QGPWGSRFPELEGVFPVGFGDS-EVSPLTIEDPKHVC 546
           NG  +   PG+     +  PP   GP G   P L+G+ P   GD  E  P  +  P+   
Sbjct: 208 NGVGQPGLPGAPGQGGAPGPPGLPGPAGLGKPGLDGL-PGAPGDKGESGPPGVPGPRG-- 264

Query: 547 DP----PSGPDTT-----PAASDLPTEQPPSPQPGPPAASHTPEKQASSFDFNGPYL-GP 596
           +P    P GP        P A+ LP  Q PS   G P  +  P        +  P L GP
Sbjct: 265 EPGAVGPKGPPGVDGVGVPGAAGLPGPQGPSGAKGEP-GTRGPPGLIGPTGYGMPGLPGP 323

Query: 597 PHSR---SLPDILG-------QPEPPQEGGSQKSPPPGSLEYLCLPAGGQVQLVPLAQAM 646
              R    +P +LG         EP ++G      PPG      LP G +    P  +A 
Sbjct: 324 KGDRGPAGVPGLLGDRGEPGEDGEPGEQGPQGLGGPPGLPGSAGLP-GRRGPPGPKGEA- 381

Query: 647 GPG-----QAVEVERRPSQGAAGSPSLESGGGPAPPALGPRVGGQDQKDSPVAIPMSSGD 701
           GPG       +  ++ PS G AG P +    G  P A GP          P   P  +G 
Sbjct: 382 GPGGPPGVPGIRGDQGPS-GLAGKPGVPGERG-LPGAHGP-----PGPTGPKGEPGFTGR 434

Query: 702 TEDPGVASGYVSSADLVFTPNSGASSVSLVPSLGLPSDQT-PSLCPGLASGPPGAPGPVK 760
              PGVA       DL      G    S +P L  P+    P   PGL  G PG PGP  
Sbjct: 435 PGGPGVAGALGQKGDLGLPGQPGLRGPSGIPGLQGPAGPIGPQGLPGL-KGEPGLPGPPG 493

Query: 761 SGFEGYVELPPIEGRSPRSPRNNPVPPEAKSPVLNPG 797
            G  G    P   G  P  P   P  P    P   PG
Sbjct: 494 EGRAGE---PGTAG--PTGPPGVPGSPGITGPPGPPG 525



 Score = 50.8 bits (120), Expect = 6e-06
 Identities = 86/318 (27%), Positives = 105/318 (33%), Gaps = 52/318 (16%)

Query: 546 CDP--PSGPDTTPAASDLPTEQPPSPQPGPPAASHTPEKQASSFDFNGPYLGPPHSRSLP 603
           C P   SG     AA   P +     Q GP        K        G YL  P      
Sbjct: 22  CGPRASSGGGAGGAAGYAPVKYIQPMQKGPVGPPFREGK--------GQYLEMPLPLLPM 73

Query: 604 DILGQPEPPQEGGSQKSP-PPG----------SLEYLCLPAGGQVQLVPLAQAMGPGQAV 652
           D+ G+P PP + G +  P PPG           L     PAG       + +A  PG   
Sbjct: 74  DLKGEPGPPGKPGPRGPPGPPGFPGKPGMGKPGLHGQPGPAGPP-GFSRMGKAGPPGLPG 132

Query: 653 EVERRPSQGAAGSPSLESGGG----PAPPAL-GPRVGGQDQKDSPVAIPMSSGDTEDPGV 707
           +V      G  G P +    G    P PP L GP       K     +P   G   +PG 
Sbjct: 133 KVGPPGQPGLRGEPGIRGDQGLRGPPGPPGLPGPSGITIPGKPGAQGVPGPPGFQGEPGP 192

Query: 708 ASGYVSSADLVFTPNSGASSVSLVPSLGLPSDQTPSLCPGLASGPPGAPGPVKSGFEGYV 767
                   D     ++G     L  + G           G A GPPG PGP   G  G  
Sbjct: 193 QGEPGPPGDRGLKGDNGVGQPGLPGAPG----------QGGAPGPPGLPGPAGLGKPGLD 242

Query: 768 ELPPIEGRSPRSPRNNPVPPEAKSPVLNPGERPADVSPTSPQ-PEGLLVLQQVGDYCFLP 826
            LP   G    S      PP    P   PG     V P  P   +G+ V    G    LP
Sbjct: 243 GLPGAPGDKGESG-----PPGVPGPRGEPGA----VGPKGPPGVDGVGVPGAAG----LP 289

Query: 827 GLGPGPLSLRSKPSSPGP 844
           G   GP   + +P + GP
Sbjct: 290 G-PQGPSGAKGEPGTRGP 306



 Score = 47.0 bits (110), Expect = 8e-05
 Identities = 82/313 (26%), Positives = 103/313 (32%), Gaps = 55/313 (17%)

Query: 496 PPGSMSAFTSGSPPHQGPWGSRFPELEGVFPVGFGDSEVSPLTIEDPKHVCDPPSGPDTT 555
           PPG +     G P   GP G R P   GV P   GD        E  +       GP   
Sbjct: 306 PPGLIGPTGYGMPGLPGPKGDRGPA--GV-PGLLGDRGEPGEDGEPGEQGPQGLGGPPGL 362

Query: 556 PAASDLPTEQ-PPSPQP-----GPPAASHTPEKQASSFDFNGPYLGPPHSRSLPDILGQP 609
           P ++ LP  + PP P+      GPP        Q  S     P  G P  R LP   G P
Sbjct: 363 PGSAGLPGRRGPPGPKGEAGPGGPPGVPGIRGDQGPSGLAGKP--GVPGERGLPGAHGPP 420

Query: 610 EPP----------QEGGSQKSPPPGSLEYLCLPA-----------GGQVQLVPLAQAMGP 648
            P           + GG   +   G    L LP            G Q    P+     P
Sbjct: 421 GPTGPKGEPGFTGRPGGPGVAGALGQKGDLGLPGQPGLRGPSGIPGLQGPAGPIGPQGLP 480

Query: 649 GQAVE--VERRPSQGAAGSPSLESGGGPAPPALGPRVGGQDQKDSPVAIPMSSGDTEDPG 706
           G   E  +   P +G AG P      GP      P + G      P   P + G  ++ G
Sbjct: 481 GLKGEPGLPGPPGEGRAGEPGTAGPTGPPGVPGSPGITGPPGPPGPPGPPGAPGAFDETG 540

Query: 707 VASGYVSSADLVFTPNSGASSVSL----VPSLG---LPSDQTPSLCPGLASGPPGAPGPV 759
           +A         +  PN G     L     P  G   L +  TP+    L S  P +  PV
Sbjct: 541 IAG--------LHLPNGGVEGAVLGKGGKPQFGLGELSAHATPAFTAVLTSPFPASGMPV 592

Query: 760 K------SGFEGY 766
           K      +G  GY
Sbjct: 593 KFDRTLYNGHSGY 605


>gi|46852161 methyl-CpG binding domain protein 6 [Homo sapiens]
          Length = 1003

 Score = 60.1 bits (144), Expect = 9e-09
 Identities = 97/380 (25%), Positives = 131/380 (34%), Gaps = 72/380 (18%)

Query: 480 NPSKSHLFQNGSAELWPPGSMSAFTSGSPPHQGPWGSRFPELEGV---FPVGFGDSEVSP 536
           +P   H    G     PP  +   T   P + GP GS  PE   V   FP   G   + P
Sbjct: 131 SPQMFHTVSPGPPSARPPCRVPPTT---PLNGGP-GSLPPEPPSVSQAFPTLAGPGGLFP 186

Query: 537 LTIEDPKHVCDPPSGPDTTPAASDLPTEQPPSPQPGPPAASHTPEKQASSFDFNGPYLGP 596
             + DP      PSG  ++P    LP    PSP P PP A       A S+++       
Sbjct: 187 PRLADPV-----PSGGSSSPRF--LPRGNAPSPAPPPPPAI---SLNAPSYNWGAAL--- 233

Query: 597 PHSRSLPDILGQPEPPQEGGSQKSPPPGSLEYLCLPAGGQVQLVPLAQAMGPGQAVEVER 656
             S  +P  LG P  P    S  S PP               L   + A+ P        
Sbjct: 234 -RSSLVPSDLGSPPAPHASSSPPSDPP---------------LFHCSDALTPPPLPPSNN 277

Query: 657 RPSQ-GAAGSPSLESGGGPAPPALGPRVGGQDQKDSPVAIPMSSGDTEDPGVASGYVSSA 715
            P+  G A  P + S     P  LGP +GG    + P A P          +AS  +S+A
Sbjct: 278 LPAHPGPASQPPVSSATMHLPLVLGP-LGGAPTVEGPGAPPF---------LASSLLSAA 327

Query: 716 DLVFTPNSGASSVSLVPSLGLPSDQTPSLCPGLASGPPGAPGPVKSGFEGYVELPP---- 771
                  + A    L P   L   +  +  P  +      P   +         PP    
Sbjct: 328 -------AKAQHPPLPPPSTLQGRRPRAQAPSASHSSSLRPSQRRP------RRPPTVFR 374

Query: 772 -IEGRSPRSPRNNPVPPEAKSPVLNPGERPADVSPTSPQPEGLLVLQQVGDYCFLPGLGP 830
            +EGR P++PR +   P A +PV  P   P    P  P    LL L   G     P    
Sbjct: 375 LLEGRGPQTPRRS--RPRAPAPVPQPFSLPEPSQPILPSVLSLLGLPTPG-----PSHSD 427

Query: 831 GPLSLRSKPSSPGPGPEIKN 850
           G  +L    +   P P + +
Sbjct: 428 GSFNLLGSDAHLPPPPTLSS 447



 Score = 53.9 bits (128), Expect = 7e-07
 Identities = 126/459 (27%), Positives = 155/459 (33%), Gaps = 128/459 (27%)

Query: 478 IPNPSKSHL-----FQNGSAELWPPGSMSAFTSGSPPHQGPWGSRFPELEGVFPVGFGDS 532
           +P P  SH           A L PP ++S   SGSPP   P     P L G      G  
Sbjct: 418 LPTPGPSHSDGSFNLLGSDAHLPPPPTLS---SGSPPQ--PRHPIQPSLPGTTS---GSL 469

Query: 533 EVSPLTIEDPKHVCDPPSGPDTTPAASDLPTEQPP---SPQPG-----PPAASHTPEKQA 584
              P              G    PAAS  P    P   SP  G      PA    P    
Sbjct: 470 SSVP--------------GAPAPPAASKAPVVPSPVLQSPSEGLGMGAGPACPLPPLAGG 515

Query: 585 SSFDFNGPYLGPPHSRS----------LPDILGQPEPPQ-----------EGGSQKSPPP 623
            +F F  P  G   S +          LP  LGQP P              GG Q  PPP
Sbjct: 516 EAFPFPSPEQGLALSGAGFPGMLGALPLPLSLGQPPPSPLLNHSLFGVLTGGGGQ--PPP 573

Query: 624 GSLEYLCLPAGGQVQLVPLAQAMGPGQAVEVERRPSQGAAGSPSLESGGGPAPP------ 677
              E L  P GG    +   +  GP   V     P       P        APP      
Sbjct: 574 ---EPLLPPPGGPGPPLAPGEPEGPSLLVASLLPPPPSDLLPPP------SAPPSNLLAS 624

Query: 678 -----ALGPRVGGQDQKDSPVAIPMSSGDTEDPGVASGYVSSADLVFTPNSGA------S 726
                ALGP  G     D   +   + G + +P   SG    + L+F P S        +
Sbjct: 625 FLPLLALGPTAG-----DGEGSAEGAGGPSGEP--FSGLGDLSPLLFPPLSAPPTLIALN 677

Query: 727 SVSLVPSLGLPSDQTPSLCPGLASGPPGAPGPVKSGFEGYVELPPIEGRSPRSPRNNPVP 786
           S  L  +L  PS   P  C  + S P   PGP  S        P       ++P N+  P
Sbjct: 678 SALLAATLDPPSGTPPQPC--VLSAPQ--PGPPTSSVTTATTDPGASSLG-KAPSNSGRP 732

Query: 787 PEAKSPVL-------------NPGERPADVSPTSPQPEGLLVLQQVGDYCFLPGLG-PGP 832
           P+  SP+L             +PG  P+ + P  P   G L LQ       LPG G P P
Sbjct: 733 PQLLSPLLGASLLGDLSSLTSSPGALPSLLQPPGPLLSGQLGLQ------LLPGGGAPPP 786

Query: 833 LSLRSKPSSPGPGPEIKNLDQAFQVKKPPGQAVPQVPVI 871
           LS  S P        +  L Q+ Q+  PP Q  P+ P +
Sbjct: 787 LSEASSP--------LACLLQSLQI--PPEQ--PEAPCL 813



 Score = 46.6 bits (109), Expect = 1e-04
 Identities = 74/277 (26%), Positives = 93/277 (33%), Gaps = 46/277 (16%)

Query: 512 GPWGSRFPELEGVFPVGFGDSEVSPLTIEDPKHVC----DPPSGPDTTPAASDLPTEQPP 567
           GP G  F  L  + P+ F      P  I     +     DPPSG    P           
Sbjct: 647 GPSGEPFSGLGDLSPLLFPPLSAPPTLIALNSALLAATLDPPSGTPPQPCVLS------- 699

Query: 568 SPQPGPPAASHTPEKQASSFDFNGPYLG--PPHSRSLPDILGQPEPPQEGGSQKSPPPGS 625
           +PQPGPP +S T     ++ D     LG  P +S   P +L     P  G S      G 
Sbjct: 700 APQPGPPTSSVT----TATTDPGASSLGKAPSNSGRPPQLLS----PLLGASLL----GD 747

Query: 626 LEYLCLPAGGQVQLVPLAQAMGPGQAVEVERRPSQGAAGSPSLESGGGPAPPALGPRVGG 685
           L  L    G    L  L Q  GP  + ++  +   G    P L     P    L      
Sbjct: 748 LSSLTSSPGA---LPSLLQPPGPLLSGQLGLQLLPGGGAPPPLSEASSPLACLLQSLQIP 804

Query: 686 QDQKDSPVAIPMSSGDTEDPGVASGYVSSADLVFTPNSGASSVSLVPSLGLPSDQTPSLC 745
            +Q ++P   P S     +P  A   +S               +L P  G P    P L 
Sbjct: 805 PEQPEAPCLPPESPASALEPEPARPPLS---------------ALAPPHGSPDPPVPELL 849

Query: 746 PGLASGPPGAPGPVKSGFEGY-VELPPIEGRSPRSPR 781
            G  SG  G  G    G  G   E  P  GR P S R
Sbjct: 850 TGRGSGKRGRRG--GGGLRGINGEARPARGRKPGSRR 884


>gi|38373671 SEC24-related protein C [Homo sapiens]
          Length = 1094

 Score = 59.7 bits (143), Expect = 1e-08
 Identities = 90/304 (29%), Positives = 113/304 (37%), Gaps = 42/304 (13%)

Query: 496 PPGSMSAF--TSGSPPH---QGPWGSRFPELEGVFPVGFGDSEVSPLTIEDPKHVCDPPS 550
           PP  MS    +SG+PP    Q P G       G F  G GD +  P +    + +  P S
Sbjct: 55  PPQGMSRAPPSSGAPPASTAQAPCGQA---AYGQF--GQGDVQNGPSSTVQMQRL--PGS 107

Query: 551 GPDTTPAASDLPTEQPPSPQP-GPPAASHTPEKQASSFDFNGPYLGPPHSRSLPDILGQP 609
            P  +P A      QPP  QP GPP  S     Q S    +G     P S  L       
Sbjct: 108 QPFGSPLAP--VGNQPPVLQPYGPPPTSAQVATQLSGMQISGAVAPAPPSSGLGF----- 160

Query: 610 EPPQEGGSQKSPPPGSLEYLCLPAGGQVQLVPLAQAMG-PGQAVEVERRPSQGAAGSPSL 668
            PP    S     P S  Y   P G   Q  PL+QA G PG        PSQ ++ +P  
Sbjct: 161 GPPTSLASASGSFPNSGLYGSYPQG---QAPPLSQAQGHPGIQTPQRSAPSQASSFTPP- 216

Query: 669 ESGGGPAPPALGPRVGGQDQKDSPVAIPMSSGDTEDPGVASGYVSSADLVFTPNSGASSV 728
            SGG   P   GP + GQ      V+ P              +VSS      P +  +  
Sbjct: 217 ASGGPRLPSMTGPLLPGQSFGGPSVSQP-------------NHVSSPPQALPPGTQMTG- 262

Query: 729 SLVPSLGLPSDQTPSLCPGLASGPPGAPGPVKSGFEGYVELPPIEGRSPRSPRNNPVPPE 788
            L P   + S Q P   P        A GP +S + G     P  G  P  P+  P+PP+
Sbjct: 263 PLGPLPPMHSPQQPGYQPQQNGSFGPARGP-QSNYGGPYPAAPTFGSQPGPPQ--PLPPK 319

Query: 789 AKSP 792
              P
Sbjct: 320 RLDP 323



 Score = 34.3 bits (77), Expect = 0.53
 Identities = 48/191 (25%), Positives = 65/191 (34%), Gaps = 38/191 (19%)

Query: 684 GGQDQKDSPVAIPMSSGDTEDPGVASGYVSSADLVFTPNSGASSVSLVPSLGLPSDQTPS 743
           GGQ    +P AIP  + +   PG             TP  G S     PS G P   T  
Sbjct: 29  GGQSGSTAP-AIPYGAYNGPVPGYQQ----------TPPQGMSRAP--PSSGAPPASTAQ 75

Query: 744 LCPGLASGPPGAPGPVKSGFEGYVELPPIEGRSPRSPRNNPVPPEAKSPVLNPGERPADV 803
              G A+      G V++G    V++  + G  P             SP+   G +P  +
Sbjct: 76  APCGQAAYGQFGQGDVQNGPSSTVQMQRLPGSQPFG-----------SPLAPVGNQPPVL 124

Query: 804 SPTSPQPEGLLVLQQVGDYCFLPGLGPGPLSLRSKPSSP---GPGPEIKNLDQAF----- 855
            P  P P    V  Q+        + P P      PSS    GP   + +   +F     
Sbjct: 125 QPYGPPPTSAQVATQLSGMQISGAVAPAP------PSSGLGFGPPTSLASASGSFPNSGL 178

Query: 856 QVKKPPGQAVP 866
               P GQA P
Sbjct: 179 YGSYPQGQAPP 189


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.315    0.134    0.423 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 48,462,245
Number of Sequences: 37866
Number of extensions: 3168155
Number of successful extensions: 20666
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 93
Number of HSP's successfully gapped in prelim test: 1321
Number of HSP's that attempted gapping in prelim test: 12830
Number of HSP's gapped (non-prelim): 5556
length of query: 897
length of database: 18,247,518
effective HSP length: 111
effective length of query: 786
effective length of database: 14,044,392
effective search space: 11038892112
effective search space used: 11038892112
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (22.0 bits)
S2: 67 (30.4 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


Home | Table of Contents | Search text | Search genes | Search sequences | Purchase | FAQ | Blog | Help

Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

CSHL Press