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Search of human proteins with 45593138
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|45593138 leucine rich repeat containing 25 [Homo sapiens]
(305 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|45593138 leucine rich repeat containing 25 [Homo sapiens] 633 0.0
gi|76880480 hypothetical protein LOC9865 [Homo sapiens] 36 0.037
gi|165932370 FAT tumor suppressor homolog 4 [Homo sapiens] 35 0.063
gi|225579152 insulin-like growth factor binding protein, acid la... 35 0.083
gi|4826772 insulin-like growth factor binding protein, acid labi... 35 0.083
gi|4759146 slit homolog 2 [Homo sapiens] 35 0.11
gi|153791466 AMIGO protein [Homo sapiens] 34 0.14
gi|4758460 glycoprotein V (platelet) [Homo sapiens] 34 0.18
gi|52353306 leucine rich repeat containing 55 [Homo sapiens] 33 0.31
gi|193083139 leucine rich repeat containing 32 precursor [Homo s... 33 0.41
gi|5031707 leucine rich repeat containing 32 precursor [Homo sap... 33 0.41
gi|7019381 fibronectin leucine rich transmembrane protein 2 [Hom... 32 0.54
gi|16418467 leucine-rich alpha-2-glycoprotein 1 [Homo sapiens] 32 0.70
gi|205277468 leucine rich repeat containing 15 isoform a [Homo s... 32 0.70
gi|18677767 leucine rich repeat containing 15 isoform b [Homo sa... 32 0.70
gi|88702793 slit-like 2 [Homo sapiens] 32 0.70
gi|157504499 ankyrin repeat domain 47 [Homo sapiens] 32 0.91
gi|62912470 leucine-rich repeat-containing G protein-coupled rec... 32 0.91
gi|4503489 ephrin-B3 precursor [Homo sapiens] 31 1.2
gi|4507531 toll-like receptor 3 [Homo sapiens] 31 1.6
gi|13562088 leucine-rich repeat-containing 3 precursor [Homo sap... 31 1.6
gi|90991702 leucine-rich repeat kinase 1 [Homo sapiens] 31 1.6
gi|51317373 netrin-G1 ligand [Homo sapiens] 31 1.6
gi|85986601 relaxin/insulin-like family peptide receptor 1 [Homo... 30 2.0
gi|126032348 hect domain and RLD 2 [Homo sapiens] 30 2.7
gi|140561027 CASK-interacting protein CIP98 isoform 2 [Homo sapi... 30 2.7
gi|140561024 CASK-interacting protein CIP98 isoform 1 [Homo sapi... 30 2.7
gi|22749183 leucine rich repeat and Ig domain containing 2 [Homo... 30 2.7
gi|40254924 leucine rich repeat containing 59 [Homo sapiens] 30 2.7
gi|66912176 leucine rich repeat containing 66 [Homo sapiens] 30 2.7
>gi|45593138 leucine rich repeat containing 25 [Homo sapiens]
Length = 305
Score = 633 bits (1632), Expect = 0.0
Identities = 305/305 (100%), Positives = 305/305 (100%)
Query: 1 MGGTLAWTLLLPLLLRESDSLEPSCTVSSADVDWNAEFSATCLNFSGLSLSLPHNQSLRA 60
MGGTLAWTLLLPLLLRESDSLEPSCTVSSADVDWNAEFSATCLNFSGLSLSLPHNQSLRA
Sbjct: 1 MGGTLAWTLLLPLLLRESDSLEPSCTVSSADVDWNAEFSATCLNFSGLSLSLPHNQSLRA 60
Query: 61 SNVILLDLSGNGLRELPVTFFAHLQKLEVLNVLRNPLSRVDGALAARCDLDLQADCNCAL 120
SNVILLDLSGNGLRELPVTFFAHLQKLEVLNVLRNPLSRVDGALAARCDLDLQADCNCAL
Sbjct: 61 SNVILLDLSGNGLRELPVTFFAHLQKLEVLNVLRNPLSRVDGALAARCDLDLQADCNCAL 120
Query: 121 ESWHDIRRDNCSGQKPLLCWDTTSSQHNLSAFLEVSCAPGLASATIGAVVVSGCLLLGLA 180
ESWHDIRRDNCSGQKPLLCWDTTSSQHNLSAFLEVSCAPGLASATIGAVVVSGCLLLGLA
Sbjct: 121 ESWHDIRRDNCSGQKPLLCWDTTSSQHNLSAFLEVSCAPGLASATIGAVVVSGCLLLGLA 180
Query: 181 IAGPVLAWRLWRCRVARSRELNKPWAAQDGPKPGLGLQPRYGSRSAPKPQVAVPSCPSTP 240
IAGPVLAWRLWRCRVARSRELNKPWAAQDGPKPGLGLQPRYGSRSAPKPQVAVPSCPSTP
Sbjct: 181 IAGPVLAWRLWRCRVARSRELNKPWAAQDGPKPGLGLQPRYGSRSAPKPQVAVPSCPSTP 240
Query: 241 DYENMFVGQPAAEHQWDEQGAHPSEDNDFYINYKDIDLASQPVYCNLQSLGQAPMDEEEY 300
DYENMFVGQPAAEHQWDEQGAHPSEDNDFYINYKDIDLASQPVYCNLQSLGQAPMDEEEY
Sbjct: 241 DYENMFVGQPAAEHQWDEQGAHPSEDNDFYINYKDIDLASQPVYCNLQSLGQAPMDEEEY 300
Query: 301 VIPGH 305
VIPGH
Sbjct: 301 VIPGH 305
>gi|76880480 hypothetical protein LOC9865 [Homo sapiens]
Length = 811
Score = 36.2 bits (82), Expect = 0.037
Identities = 27/73 (36%), Positives = 33/73 (45%), Gaps = 14/73 (19%)
Query: 66 LDLSGNGLRELPVTFFAHLQKLEVLNVLRNPLSRVDGALAA------RCDLDLQA-DCNC 118
LDLSGN L L F HL +L L++ N LS + G + A R DLD C+C
Sbjct: 306 LDLSGNELSALHPATFGHLGRLRELSLRNNALSALSGDIFAASPALYRLDLDGNGWTCDC 365
Query: 119 ALE-------SWH 124
L WH
Sbjct: 366 RLRGLKRWMGDWH 378
>gi|165932370 FAT tumor suppressor homolog 4 [Homo sapiens]
Length = 4981
Score = 35.4 bits (80), Expect = 0.063
Identities = 29/90 (32%), Positives = 43/90 (47%), Gaps = 7/90 (7%)
Query: 3 GTLAWTLLLPLLLRESDSLEPSC----TVSSADVDWNAEFSATCLNFSGLSLSLPHNQSL 58
GT+ ++L R S L+P T+SS D + A +S L L P S+
Sbjct: 616 GTVRFSLQEAETDRRSFRLDPVSGRLSTISSLDREEQAFYSLLVL---ATDLGSPPQSSM 672
Query: 59 RASNVILLDLSGNGLRELPVTFFAHLQKLE 88
NV LLD++ N PV +FAH+++ E
Sbjct: 673 ARINVSLLDINDNSPVFYPVQYFAHIKENE 702
>gi|225579152 insulin-like growth factor binding protein, acid
labile subunit isoform 1 precursor [Homo sapiens]
Length = 643
Score = 35.0 bits (79), Expect = 0.083
Identities = 26/69 (37%), Positives = 36/69 (52%), Gaps = 12/69 (17%)
Query: 44 NFSGLS----LSLPHNQS--------LRASNVILLDLSGNGLRELPVTFFAHLQKLEVLN 91
+F GL L+L HNQ L +NV +++LSGN LR LP F L KL L+
Sbjct: 371 SFEGLGQLEVLTLDHNQLQEVKAGAFLGLTNVAVMNLSGNCLRNLPEQVFRGLGKLHSLH 430
Query: 92 VLRNPLSRV 100
+ + L R+
Sbjct: 431 LEGSCLGRI 439
Score = 31.6 bits (70), Expect = 0.91
Identities = 24/63 (38%), Positives = 29/63 (46%), Gaps = 1/63 (1%)
Query: 43 LNFSGLSL-SLPHNQSLRASNVILLDLSGNGLRELPVTFFAHLQKLEVLNVLRNPLSRVD 101
LN G L SL L N+ L L N LR L + FAH L L + N LSR++
Sbjct: 141 LNLQGGQLGSLEPQALLGLENLCHLHLERNQLRSLALGTFAHTPALASLGLSNNRLSRLE 200
Query: 102 GAL 104
L
Sbjct: 201 DGL 203
Score = 28.9 bits (63), Expect = 5.9
Identities = 16/40 (40%), Positives = 23/40 (57%)
Query: 61 SNVILLDLSGNGLRELPVTFFAHLQKLEVLNVLRNPLSRV 100
+ ++ LDL+ N L LP F L KLE L + RN L+ +
Sbjct: 472 AELLELDLTSNQLTHLPHRLFQGLGKLEYLLLSRNRLAEL 511
>gi|4826772 insulin-like growth factor binding protein, acid labile
subunit isoform 2 precursor [Homo sapiens]
Length = 605
Score = 35.0 bits (79), Expect = 0.083
Identities = 26/69 (37%), Positives = 36/69 (52%), Gaps = 12/69 (17%)
Query: 44 NFSGLS----LSLPHNQS--------LRASNVILLDLSGNGLRELPVTFFAHLQKLEVLN 91
+F GL L+L HNQ L +NV +++LSGN LR LP F L KL L+
Sbjct: 333 SFEGLGQLEVLTLDHNQLQEVKAGAFLGLTNVAVMNLSGNCLRNLPEQVFRGLGKLHSLH 392
Query: 92 VLRNPLSRV 100
+ + L R+
Sbjct: 393 LEGSCLGRI 401
Score = 31.6 bits (70), Expect = 0.91
Identities = 24/63 (38%), Positives = 29/63 (46%), Gaps = 1/63 (1%)
Query: 43 LNFSGLSL-SLPHNQSLRASNVILLDLSGNGLRELPVTFFAHLQKLEVLNVLRNPLSRVD 101
LN G L SL L N+ L L N LR L + FAH L L + N LSR++
Sbjct: 103 LNLQGGQLGSLEPQALLGLENLCHLHLERNQLRSLALGTFAHTPALASLGLSNNRLSRLE 162
Query: 102 GAL 104
L
Sbjct: 163 DGL 165
Score = 28.9 bits (63), Expect = 5.9
Identities = 16/40 (40%), Positives = 23/40 (57%)
Query: 61 SNVILLDLSGNGLRELPVTFFAHLQKLEVLNVLRNPLSRV 100
+ ++ LDL+ N L LP F L KLE L + RN L+ +
Sbjct: 434 AELLELDLTSNQLTHLPHRLFQGLGKLEYLLLSRNRLAEL 473
>gi|4759146 slit homolog 2 [Homo sapiens]
Length = 1529
Score = 34.7 bits (78), Expect = 0.11
Identities = 30/100 (30%), Positives = 51/100 (51%), Gaps = 16/100 (16%)
Query: 4 TLAWTLLLPLLLRESDSLEPS-CTVSSADVDWNAEFSATCLNFSGLSL-SLPHNQSLRAS 61
+L+ L+L +L + + P+ C+ S + VD + GL+L S+P N
Sbjct: 10 SLSLGLVLAILNKVAPQACPAQCSCSGSTVDCH-----------GLALRSVPRNIP---R 55
Query: 62 NVILLDLSGNGLRELPVTFFAHLQKLEVLNVLRNPLSRVD 101
N LDL+GN + + T FA L+ L VL ++ N +S ++
Sbjct: 56 NTERLDLNGNNITRITKTDFAGLRHLRVLQLMENKISTIE 95
>gi|153791466 AMIGO protein [Homo sapiens]
Length = 493
Score = 34.3 bits (77), Expect = 0.14
Identities = 26/67 (38%), Positives = 31/67 (46%), Gaps = 5/67 (7%)
Query: 62 NVILLDLSGNGLRELPVTFFAHLQKLEVLNVLRNPLSRVDGALAARCDLDLQADCNCALE 121
N+ LDLS N LR L F+ LQ LEVL + N + VD RC D A
Sbjct: 111 NLRYLDLSSNQLRTLDEFLFSDLQVLEVLLLYNNHIMAVD-----RCAFDDMAQLQKLYL 165
Query: 122 SWHDIRR 128
S + I R
Sbjct: 166 SQNQISR 172
>gi|4758460 glycoprotein V (platelet) [Homo sapiens]
Length = 560
Score = 33.9 bits (76), Expect = 0.18
Identities = 18/46 (39%), Positives = 23/46 (50%)
Query: 59 RASNVILLDLSGNGLRELPVTFFAHLQKLEVLNVLRNPLSRVDGAL 104
R N+ L LS N L LP F H L +L + NPL+ + G L
Sbjct: 240 RLPNLSSLTLSRNHLAFLPSALFLHSHNLTLLTLFENPLAELPGVL 285
Score = 32.3 bits (72), Expect = 0.54
Identities = 21/53 (39%), Positives = 25/53 (47%)
Query: 52 LPHNQSLRASNVILLDLSGNGLRELPVTFFAHLQKLEVLNVLRNPLSRVDGAL 104
LP + N+ LLDLSGN L LP KLE L + N L +D L
Sbjct: 161 LPASLFTNLENLKLLDLSGNNLTHLPKGLLGAQAKLERLLLHSNRLVSLDSGL 213
>gi|52353306 leucine rich repeat containing 55 [Homo sapiens]
Length = 341
Score = 33.1 bits (74), Expect = 0.31
Identities = 57/209 (27%), Positives = 85/209 (40%), Gaps = 35/209 (16%)
Query: 8 TLLLPLLLRESD---SLEPSCTVSSADVDWNAE--FSATC-LNFSGLSLSLPHNQSLRAS 61
+LLL L SD S CT + VD +++ FS L +LSL HN+
Sbjct: 65 SLLLAAGLMHSDAGTSCPVLCTCRNQVVDCSSQRLFSVPPDLPMDTRNLSLAHNRITAVP 124
Query: 62 --------NVILLDLSGNGLRELPVTFFAHLQKLEVLNVLRNPLSRVDGALAARCDLDLQ 113
+ +LDL N L ELP F H ++L L++ N S V D+ +
Sbjct: 125 PGYLTCYMELQVLDLHNNSLMELPRGLFLHAKRLAHLDLSYNNFSHVP------ADMFQE 178
Query: 114 ADCNCALESWHD--IRRDNCSGQKPLLCWDTTSSQHNLSAFLEVSC---APGLASATIGA 168
A ++ H+ +RR + + L+ + AFL + PGL + IG
Sbjct: 179 AHGLVHIDLSHNPWLRRVHPQAFQGLMQLRDLDLSYGGLAFLSLEALEGLPGLVTLQIGG 238
Query: 169 -VVVSGCLLLGLAIAGPVLAW---RLWRC 193
V GC + P+L W R+ RC
Sbjct: 239 NPWVCGCTM------EPLLKWLRNRIQRC 261
>gi|193083139 leucine rich repeat containing 32 precursor [Homo
sapiens]
Length = 662
Score = 32.7 bits (73), Expect = 0.41
Identities = 32/83 (38%), Positives = 42/83 (50%), Gaps = 6/83 (7%)
Query: 45 FSGLSLSLPH-NQSLRA-SNVILLDLSGNGLRELPVTFFAHLQKLEVLNVLRNPL----S 98
+S L LS P N S R S ++ LDLS N + +P +F HL L LN+ RN L +
Sbjct: 297 WSALPLSAPSGNASGRPLSQLLNLDLSYNEIELIPDSFLEHLTSLCFLNLSRNCLRTFEA 356
Query: 99 RVDGALAARCDLDLQADCNCALE 121
R G+L LDL + LE
Sbjct: 357 RRLGSLPCLMLLDLSHNALETLE 379
Score = 30.4 bits (67), Expect = 2.0
Identities = 16/35 (45%), Positives = 21/35 (60%)
Query: 68 LSGNGLRELPVTFFAHLQKLEVLNVLRNPLSRVDG 102
L GN LR+LP FA+L L+ LN+ N +S G
Sbjct: 393 LQGNALRDLPPYTFANLASLQRLNLQGNRVSPCGG 427
>gi|5031707 leucine rich repeat containing 32 precursor [Homo
sapiens]
Length = 662
Score = 32.7 bits (73), Expect = 0.41
Identities = 32/83 (38%), Positives = 42/83 (50%), Gaps = 6/83 (7%)
Query: 45 FSGLSLSLPH-NQSLRA-SNVILLDLSGNGLRELPVTFFAHLQKLEVLNVLRNPL----S 98
+S L LS P N S R S ++ LDLS N + +P +F HL L LN+ RN L +
Sbjct: 297 WSALPLSAPSGNASGRPLSQLLNLDLSYNEIELIPDSFLEHLTSLCFLNLSRNCLRTFEA 356
Query: 99 RVDGALAARCDLDLQADCNCALE 121
R G+L LDL + LE
Sbjct: 357 RRLGSLPCLMLLDLSHNALETLE 379
Score = 30.4 bits (67), Expect = 2.0
Identities = 16/35 (45%), Positives = 21/35 (60%)
Query: 68 LSGNGLRELPVTFFAHLQKLEVLNVLRNPLSRVDG 102
L GN LR+LP FA+L L+ LN+ N +S G
Sbjct: 393 LQGNALRDLPPYTFANLASLQRLNLQGNRVSPCGG 427
>gi|7019381 fibronectin leucine rich transmembrane protein 2 [Homo
sapiens]
Length = 660
Score = 32.3 bits (72), Expect = 0.54
Identities = 20/54 (37%), Positives = 32/54 (59%), Gaps = 1/54 (1%)
Query: 45 FSGLSLSLPHNQ-SLRASNVILLDLSGNGLRELPVTFFAHLQKLEVLNVLRNPL 97
FS + SL H L +++I L L N + +P+T F++L+KLE L++ N L
Sbjct: 235 FSIVRNSLSHPPPDLPGTHLIRLYLQDNQINHIPLTAFSNLRKLERLDISNNQL 288
>gi|16418467 leucine-rich alpha-2-glycoprotein 1 [Homo sapiens]
Length = 347
Score = 32.0 bits (71), Expect = 0.70
Identities = 23/61 (37%), Positives = 30/61 (49%), Gaps = 1/61 (1%)
Query: 52 LPHNQSLRASNVILLDLSGNGLRELPVTFFAHLQKLEVLNVLRNPLSRV-DGALAARCDL 110
LP N AS + L LS NGL L F + +L VL++ RN L+ + G A L
Sbjct: 83 LPANLLQGASKLQELHLSSNGLESLSPEFLRPVPQLRVLDLTRNALTGLPPGLFQASATL 142
Query: 111 D 111
D
Sbjct: 143 D 143
Score = 28.5 bits (62), Expect = 7.7
Identities = 15/32 (46%), Positives = 19/32 (59%)
Query: 66 LDLSGNGLRELPVTFFAHLQKLEVLNVLRNPL 97
LDLSGN LR+LP A+ L L++ N L
Sbjct: 169 LDLSGNRLRKLPPGLLANFTLLRTLDLGENQL 200
>gi|205277468 leucine rich repeat containing 15 isoform a [Homo
sapiens]
Length = 587
Score = 32.0 bits (71), Expect = 0.70
Identities = 20/61 (32%), Positives = 27/61 (44%), Gaps = 9/61 (14%)
Query: 52 LPHNQSLRASNVILLDLSGNGLRELPVTFFAHLQKLEVLNVLRNPLSRVDGALAARCDLD 111
LP N + ++ + L N L LP+ F HL KL L + NP RCD D
Sbjct: 386 LPGNIFANVNGLMAIQLQNNQLENLPLGIFDHLGKLCELRLYDNPW---------RCDSD 436
Query: 112 L 112
+
Sbjct: 437 I 437
Score = 29.6 bits (65), Expect = 3.5
Identities = 25/68 (36%), Positives = 32/68 (47%), Gaps = 12/68 (17%)
Query: 45 FSGL----SLSLPHNQSLR--------ASNVILLDLSGNGLRELPVTFFAHLQKLEVLNV 92
F GL SL L NQ L+ SN+ L L GN L +P F HL L LN+
Sbjct: 127 FQGLDSLESLLLSSNQLLQIQPAHFSQCSNLKELQLHGNHLEYIPDGAFDHLVGLTKLNL 186
Query: 93 LRNPLSRV 100
+N L+ +
Sbjct: 187 GKNSLTHI 194
>gi|18677767 leucine rich repeat containing 15 isoform b [Homo
sapiens]
Length = 581
Score = 32.0 bits (71), Expect = 0.70
Identities = 20/61 (32%), Positives = 27/61 (44%), Gaps = 9/61 (14%)
Query: 52 LPHNQSLRASNVILLDLSGNGLRELPVTFFAHLQKLEVLNVLRNPLSRVDGALAARCDLD 111
LP N + ++ + L N L LP+ F HL KL L + NP RCD D
Sbjct: 380 LPGNIFANVNGLMAIQLQNNQLENLPLGIFDHLGKLCELRLYDNPW---------RCDSD 430
Query: 112 L 112
+
Sbjct: 431 I 431
Score = 29.6 bits (65), Expect = 3.5
Identities = 25/68 (36%), Positives = 32/68 (47%), Gaps = 12/68 (17%)
Query: 45 FSGL----SLSLPHNQSLR--------ASNVILLDLSGNGLRELPVTFFAHLQKLEVLNV 92
F GL SL L NQ L+ SN+ L L GN L +P F HL L LN+
Sbjct: 121 FQGLDSLESLLLSSNQLLQIQPAHFSQCSNLKELQLHGNHLEYIPDGAFDHLVGLTKLNL 180
Query: 93 LRNPLSRV 100
+N L+ +
Sbjct: 181 GKNSLTHI 188
>gi|88702793 slit-like 2 [Homo sapiens]
Length = 673
Score = 32.0 bits (71), Expect = 0.70
Identities = 23/60 (38%), Positives = 30/60 (50%), Gaps = 7/60 (11%)
Query: 48 LSLSLPHNQSLR-------ASNVILLDLSGNGLRELPVTFFAHLQKLEVLNVLRNPLSRV 100
L L L HN L +NV L L+G GL++L F+ L+ L L+V N L RV
Sbjct: 172 LLLDLSHNSLLALEPGILDTANVEALRLAGLGLQQLDEGLFSRLRNLHDLDVSDNQLERV 231
>gi|157504499 ankyrin repeat domain 47 [Homo sapiens]
Length = 821
Score = 31.6 bits (70), Expect = 0.91
Identities = 29/82 (35%), Positives = 38/82 (46%), Gaps = 7/82 (8%)
Query: 158 APGLASATIGAVVVSGCLLLGLAIAGPVLAWRLWRCRVARSRELNKPWAAQDGPKPGLGL 217
APG+ S GA SG L+ L+ PV R+ SR L + P PG G+
Sbjct: 102 APGILSQ--GAP--SGLLMQPLSPRAPVRNPRVEHTLRETSRRLELAQTHERAPSPGRGV 157
Query: 218 --QPRYGSRSAPKPQVAVPSCP 237
PR RS+P P +A P+ P
Sbjct: 158 PRSPRGSGRSSPAPNLA-PASP 178
>gi|62912470 leucine-rich repeat-containing G protein-coupled
receptor 6 isoform 1 [Homo sapiens]
Length = 967
Score = 31.6 bits (70), Expect = 0.91
Identities = 18/37 (48%), Positives = 21/37 (56%)
Query: 66 LDLSGNGLRELPVTFFAHLQKLEVLNVLRNPLSRVDG 102
LDLS N L EL F HL+ LE L + N LS + G
Sbjct: 71 LDLSMNNLTELQPGLFHHLRFLEELRLSGNHLSHIPG 107
>gi|4503489 ephrin-B3 precursor [Homo sapiens]
Length = 340
Score = 31.2 bits (69), Expect = 1.2
Identities = 33/112 (29%), Positives = 44/112 (39%), Gaps = 10/112 (8%)
Query: 141 DTTSSQHNLSAFLEVSCAPGLASATIGAVVVSGCLLLGLAIAGPVLAWRLWRCRVARSRE 200
D TS+ + A E P A GA LLLG+A AG + WR R + + SR
Sbjct: 206 DPTSNATSRGA--EGPLPPPSMPAVAGAAGGLALLLLGVAGAGGAMCWRRRRAKPSESRH 263
Query: 201 LNKPWAAQDGPKPGLGLQPRYGSRSAPKPQVAV-------PSCPSTPDYENM 245
P + G GLG G R A ++ + P P YE +
Sbjct: 264 PG-PGSFGRGGSLGLGGGGGMGPREAEPGELGIALRGGGAADPPFCPHYEKV 314
>gi|4507531 toll-like receptor 3 [Homo sapiens]
Length = 904
Score = 30.8 bits (68), Expect = 1.6
Identities = 14/39 (35%), Positives = 24/39 (61%)
Query: 62 NVILLDLSGNGLRELPVTFFAHLQKLEVLNVLRNPLSRV 100
N+ +LDLS N + + L+KLE+L++ N L+R+
Sbjct: 507 NLTILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARL 545
Score = 29.6 bits (65), Expect = 3.5
Identities = 19/67 (28%), Positives = 33/67 (49%), Gaps = 8/67 (11%)
Query: 65 LLDLSGNGLRELPVTFFAHLQKLEVLNVLRNPLSRVD-----GALAARCDLDLQ---ADC 116
++DL N L LP + F + L+ LN+ +N ++ V+ A +LD++ DC
Sbjct: 590 IIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLITSVEKKVFGPAFRNLTELDMRFNPFDC 649
Query: 117 NCALESW 123
C +W
Sbjct: 650 TCESIAW 656
Score = 28.5 bits (62), Expect = 7.7
Identities = 19/64 (29%), Positives = 30/64 (46%), Gaps = 6/64 (9%)
Query: 40 ATCLNFSGLSL------SLPHNQSLRASNVILLDLSGNGLRELPVTFFAHLQKLEVLNVL 93
A C N + L L + +N ++ N+I LDLS NGL + L+ L+ L +
Sbjct: 120 AFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQLENLQELLLS 179
Query: 94 RNPL 97
N +
Sbjct: 180 NNKI 183
Score = 28.5 bits (62), Expect = 7.7
Identities = 13/44 (29%), Positives = 28/44 (63%)
Query: 61 SNVILLDLSGNGLRELPVTFFAHLQKLEVLNVLRNPLSRVDGAL 104
S++ +L+L NG E+PV F L +L+++++ N L+ + ++
Sbjct: 562 SHLHILNLESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASV 605
>gi|13562088 leucine-rich repeat-containing 3 precursor [Homo
sapiens]
Length = 257
Score = 30.8 bits (68), Expect = 1.6
Identities = 15/46 (32%), Positives = 23/46 (50%)
Query: 61 SNVILLDLSGNGLRELPVTFFAHLQKLEVLNVLRNPLSRVDGALAA 106
+N +LL L N + LP F HL +L L++ N + + A A
Sbjct: 64 ANTVLLKLDANKISHLPDGAFQHLHRLRELDLSHNAIEAIGSATFA 109
>gi|90991702 leucine-rich repeat kinase 1 [Homo sapiens]
Length = 2015
Score = 30.8 bits (68), Expect = 1.6
Identities = 16/32 (50%), Positives = 18/32 (56%)
Query: 66 LDLSGNGLRELPVTFFAHLQKLEVLNVLRNPL 97
LD+S N L ELP F + L LNV RN L
Sbjct: 385 LDISDNKLTELPALFLHSFKSLNSLNVSRNNL 416
>gi|51317373 netrin-G1 ligand [Homo sapiens]
Length = 640
Score = 30.8 bits (68), Expect = 1.6
Identities = 14/42 (33%), Positives = 26/42 (61%)
Query: 60 ASNVILLDLSGNGLRELPVTFFAHLQKLEVLNVLRNPLSRVD 101
++N LL+L N ++ + V F HL+ LE+L + RN + ++
Sbjct: 75 STNTRLLNLHENQIQIIKVNSFKHLRHLEILQLSRNHIRTIE 116
>gi|85986601 relaxin/insulin-like family peptide receptor 1 [Homo
sapiens]
Length = 757
Score = 30.4 bits (67), Expect = 2.0
Identities = 13/35 (37%), Positives = 20/35 (57%)
Query: 66 LDLSGNGLRELPVTFFAHLQKLEVLNVLRNPLSRV 100
LDL N + LP F L++L LN+ NP+ ++
Sbjct: 300 LDLGSNKIENLPPLIFKDLKELSQLNLSYNPIQKI 334
>gi|126032348 hect domain and RLD 2 [Homo sapiens]
Length = 4834
Score = 30.0 bits (66), Expect = 2.7
Identities = 19/55 (34%), Positives = 27/55 (49%), Gaps = 1/55 (1%)
Query: 162 ASATIGAVVVSGCLLLGLAIAGPVLAWRLWRCRVARSRELNKPWAAQDGPKPGLG 216
ASAT+ + L ++GP LA + + R ++ W QDGP PGLG
Sbjct: 1839 ASATVLEETRKETAPVQLPVSGPELA-AMMKIGTRVMRGVDWKWGDQDGPPPGLG 1892
>gi|140561027 CASK-interacting protein CIP98 isoform 2 [Homo
sapiens]
Length = 524
Score = 30.0 bits (66), Expect = 2.7
Identities = 17/47 (36%), Positives = 22/47 (46%)
Query: 130 NCSGQKPLLCWDTTSSQHNLSAFLEVSCAPGLASATIGAVVVSGCLL 176
N S ++PL +QH + F V P L S + A V GCLL
Sbjct: 275 NPSSKRPLDAHLALVNQHPIGPFPRVQSPPHLKSPSAEATVAGGCLL 321
>gi|140561024 CASK-interacting protein CIP98 isoform 1 [Homo
sapiens]
Length = 907
Score = 30.0 bits (66), Expect = 2.7
Identities = 17/47 (36%), Positives = 22/47 (46%)
Query: 130 NCSGQKPLLCWDTTSSQHNLSAFLEVSCAPGLASATIGAVVVSGCLL 176
N S ++PL +QH + F V P L S + A V GCLL
Sbjct: 658 NPSSKRPLDAHLALVNQHPIGPFPRVQSPPHLKSPSAEATVAGGCLL 704
>gi|22749183 leucine rich repeat and Ig domain containing 2 [Homo
sapiens]
Length = 606
Score = 30.0 bits (66), Expect = 2.7
Identities = 17/53 (32%), Positives = 27/53 (50%), Gaps = 1/53 (1%)
Query: 52 LPHNQSLRASNVILLDLSGNGLRELPVTFFAHLQKLEVLNVLRNPLSRVDGAL 104
+P N SL N+ L ++ L +P F HL L LN+ NP+S ++ +
Sbjct: 241 MPAN-SLYGLNLTSLSVTNTNLSTVPFLAFKHLVYLTHLNLSYNPISTIEAGM 292
>gi|40254924 leucine rich repeat containing 59 [Homo sapiens]
Length = 307
Score = 30.0 bits (66), Expect = 2.7
Identities = 29/102 (28%), Positives = 44/102 (43%), Gaps = 23/102 (22%)
Query: 40 ATCLNFSGLSLSLPHNQSLRASNVILLDLSGNGLRELPVTF------------------- 80
AT L+ S L+ + ++++ LDLS N L++LP F
Sbjct: 41 ATILDLSCNKLTTLPSDFCGLTHLVKLDLSKNKLQQLPADFGRLVNLQHLDLLNNKLVTL 100
Query: 81 ---FAHLQKLEVLNVLRNPLSRVDGALAARCDLDLQADCNCA 119
FA L+ L+ L++ NPL V +A C LD + CA
Sbjct: 101 PVSFAQLKNLKWLDLKDNPLDPVLAKVAGDC-LDEKQCKQCA 141
>gi|66912176 leucine rich repeat containing 66 [Homo sapiens]
Length = 880
Score = 30.0 bits (66), Expect = 2.7
Identities = 22/73 (30%), Positives = 32/73 (43%), Gaps = 12/73 (16%)
Query: 66 LDLSGNGLRELPVTFFAHLQKLEVLNVLRNPLSRVDGALAARCDLDLQADCNCALESWHD 125
LDLS N + ++ ++ FA+L LEVLN+ N + L D SW
Sbjct: 90 LDLSNNLISKITLSPFAYLHALEVLNLSNNAIH------------SLSLDLLSPKSSWVK 137
Query: 126 IRRDNCSGQKPLL 138
R + + PLL
Sbjct: 138 RHRSSFRNRFPLL 150
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.318 0.134 0.428
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 13,076,605
Number of Sequences: 37866
Number of extensions: 628277
Number of successful extensions: 2127
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 41
Number of HSP's successfully gapped in prelim test: 37
Number of HSP's that attempted gapping in prelim test: 2004
Number of HSP's gapped (non-prelim): 168
length of query: 305
length of database: 18,247,518
effective HSP length: 102
effective length of query: 203
effective length of database: 14,385,186
effective search space: 2920192758
effective search space used: 2920192758
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.