BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|13128972 collectin sub-family member 11 isoform a [Homo sapiens] (271 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|13128972 collectin sub-family member 11 isoform a [Homo sapiens] 559 e-160 gi|40548420 collectin sub-family member 11 isoform b [Homo sapiens] 427 e-120 gi|5453619 collectin sub-family member 10 [Homo sapiens] 278 5e-75 gi|61699226 pulmonary surfactant-associated protein D precursor ... 134 6e-32 gi|4557739 soluble mannose-binding lectin precursor [Homo sapiens] 111 6e-25 gi|148886696 surfactant protein A2 [Homo sapiens] 107 1e-23 gi|146149162 surfactant, pulmonary-associated protein A2 [Homo s... 107 1e-23 gi|38888175 surfactant, pulmonary-associated protein A1B [Homo s... 105 4e-23 gi|147903070 surfactant protein A1 [Homo sapiens] 100 1e-21 gi|18641360 collectin sub-family member 12 [Homo sapiens] 100 1e-21 gi|89276751 alpha 1 type V collagen preproprotein [Homo sapiens] 89 5e-18 gi|111118976 collagen, type II, alpha 1 isoform 1 precursor [Hom... 86 4e-17 gi|111118974 collagen, type II, alpha 1 isoform 2 precursor [Hom... 86 4e-17 gi|111118972 collagen, type XI, alpha 2 isoform 2 preproprotein ... 84 2e-16 gi|111118968 collagen, type XI, alpha 2 isoform 3 preproprotein ... 84 2e-16 gi|111118970 collagen, type XI, alpha 2 isoform 1 preproprotein ... 84 2e-16 gi|119829187 alpha 1 type XVII collagen [Homo sapiens] 81 8e-16 gi|98986321 gliomedin [Homo sapiens] 81 1e-15 gi|18780273 collagen, type XXI, alpha 1 precursor [Homo sapiens] 80 2e-15 gi|73486666 alpha 1 type IX collagen isoform 1 precursor [Homo s... 80 2e-15 gi|89142737 alpha 3 type IV collagen isoform 5 precursor [Homo s... 80 2e-15 gi|89142735 alpha 3 type IV collagen isoform 4 precursor [Homo s... 80 2e-15 gi|89142733 alpha 3 type IV collagen isoform 2 precursor [Homo s... 80 2e-15 gi|89142730 alpha 3 type IV collagen isoform 1 precursor [Homo s... 80 2e-15 gi|73486664 alpha 1 type IX collagen isoform 2 precursor [Homo s... 80 2e-15 gi|29725624 collagen, type XXIII, alpha 1 [Homo sapiens] 80 2e-15 gi|148536825 alpha 1 type IV collagen preproprotein [Homo sapiens] 80 2e-15 gi|13994280 C1q and tumor necrosis factor related protein 7 isof... 80 2e-15 gi|206597454 C1q and tumor necrosis factor related protein 7 iso... 80 2e-15 gi|206597452 C1q and tumor necrosis factor related protein 7 iso... 80 2e-15 >gi|13128972 collectin sub-family member 11 isoform a [Homo sapiens] Length = 271 Score = 559 bits (1441), Expect = e-160 Identities = 271/271 (100%), Positives = 271/271 (100%) Query: 1 MRGNLALVGVLISLAFLSLLPSGHPQPAGDDACSVQILVPGLKGDAGEKGDKGAPGRPGR 60 MRGNLALVGVLISLAFLSLLPSGHPQPAGDDACSVQILVPGLKGDAGEKGDKGAPGRPGR Sbjct: 1 MRGNLALVGVLISLAFLSLLPSGHPQPAGDDACSVQILVPGLKGDAGEKGDKGAPGRPGR 60 Query: 61 VGPTGEKGDMGDKGQKGSVGRHGKIGPIGSKGEKGDSGDIGPPGPNGEPGLPCECSQLRK 120 VGPTGEKGDMGDKGQKGSVGRHGKIGPIGSKGEKGDSGDIGPPGPNGEPGLPCECSQLRK Sbjct: 61 VGPTGEKGDMGDKGQKGSVGRHGKIGPIGSKGEKGDSGDIGPPGPNGEPGLPCECSQLRK 120 Query: 121 AIGEMDNQVSQLTSELKFIKNAVAGVRETESKIYLLVKEEKRYADAQLSCQGRGGTLSMP 180 AIGEMDNQVSQLTSELKFIKNAVAGVRETESKIYLLVKEEKRYADAQLSCQGRGGTLSMP Sbjct: 121 AIGEMDNQVSQLTSELKFIKNAVAGVRETESKIYLLVKEEKRYADAQLSCQGRGGTLSMP 180 Query: 181 KDEAANGLMAAYLAQAGLARVFIGINDLEKEGAFVYSDHSPMRTFNKWRSGEPNNAYDEE 240 KDEAANGLMAAYLAQAGLARVFIGINDLEKEGAFVYSDHSPMRTFNKWRSGEPNNAYDEE Sbjct: 181 KDEAANGLMAAYLAQAGLARVFIGINDLEKEGAFVYSDHSPMRTFNKWRSGEPNNAYDEE 240 Query: 241 DCVEMVASGGWNDVACHTTMYFMCEFDKENM 271 DCVEMVASGGWNDVACHTTMYFMCEFDKENM Sbjct: 241 DCVEMVASGGWNDVACHTTMYFMCEFDKENM 271 >gi|40548420 collectin sub-family member 11 isoform b [Homo sapiens] Length = 268 Score = 427 bits (1099), Expect = e-120 Identities = 205/207 (99%), Positives = 206/207 (99%) Query: 65 GEKGDMGDKGQKGSVGRHGKIGPIGSKGEKGDSGDIGPPGPNGEPGLPCECSQLRKAIGE 124 G +GDMGDKGQKGSVGRHGKIGPIGSKGEKGDSGDIGPPGPNGEPGLPCECSQLRKAIGE Sbjct: 62 GSQGDMGDKGQKGSVGRHGKIGPIGSKGEKGDSGDIGPPGPNGEPGLPCECSQLRKAIGE 121 Query: 125 MDNQVSQLTSELKFIKNAVAGVRETESKIYLLVKEEKRYADAQLSCQGRGGTLSMPKDEA 184 MDNQVSQLTSELKFIKNAVAGVRETESKIYLLVKEEKRYADAQLSCQGRGGTLSMPKDEA Sbjct: 122 MDNQVSQLTSELKFIKNAVAGVRETESKIYLLVKEEKRYADAQLSCQGRGGTLSMPKDEA 181 Query: 185 ANGLMAAYLAQAGLARVFIGINDLEKEGAFVYSDHSPMRTFNKWRSGEPNNAYDEEDCVE 244 ANGLMAAYLAQAGLARVFIGINDLEKEGAFVYSDHSPMRTFNKWRSGEPNNAYDEEDCVE Sbjct: 182 ANGLMAAYLAQAGLARVFIGINDLEKEGAFVYSDHSPMRTFNKWRSGEPNNAYDEEDCVE 241 Query: 245 MVASGGWNDVACHTTMYFMCEFDKENM 271 MVASGGWNDVACHTTMYFMCEFDKENM Sbjct: 242 MVASGGWNDVACHTTMYFMCEFDKENM 268 >gi|5453619 collectin sub-family member 10 [Homo sapiens] Length = 277 Score = 278 bits (710), Expect = 5e-75 Identities = 128/269 (47%), Positives = 183/269 (68%), Gaps = 1/269 (0%) Query: 1 MRGNLALVGVLISLAFLSLLPSGHPQPAGDDACSVQILVPGLKGDAGEKGDKGAPGRPGR 60 +R N ++ VL L SL +P + C+ + PG KGD GEKGD G G+ G+ Sbjct: 8 LRRNQFILLVLFLLQIQSLGLDIDSRPTAE-VCATHTISPGPKGDDGEKGDPGEEGKHGK 66 Query: 61 VGPTGEKGDMGDKGQKGSVGRHGKIGPIGSKGEKGDSGDIGPPGPNGEPGLPCECSQLRK 120 VG G KG G+ G G G GK GPIG KG+KG+ G +G PG G+ G C+C + RK Sbjct: 67 VGRMGPKGIKGELGDMGDRGNIGKTGPIGKKGDKGEKGLLGIPGEKGKAGTVCDCGRYRK 126 Query: 121 AIGEMDNQVSQLTSELKFIKNAVAGVRETESKIYLLVKEEKRYADAQLSCQGRGGTLSMP 180 +G++D +++L + +KF+KN +AG+RETE K Y +V+EEK Y ++ C+ RGG L+MP Sbjct: 127 FVGQLDISIARLKTSMKFVKNVIAGIRETEEKFYYIVQEEKNYRESLTHCRIRGGMLAMP 186 Query: 181 KDEAANGLMAAYLAQAGLARVFIGINDLEKEGAFVYSDHSPMRTFNKWRSGEPNNAYDEE 240 KDEAAN L+A Y+A++G RVFIG+NDLE+EG ++++D++P++ ++ W GEP++ Y E Sbjct: 187 KDEAANTLIADYVAKSGFFRVFIGVNDLEREGQYMFTDNTPLQNYSNWNEGEPSDPYGHE 246 Query: 241 DCVEMVASGGWNDVACHTTMYFMCEFDKE 269 DCVEM++SG WND CH TMYF+CEF K+ Sbjct: 247 DCVEMLSSGRWNDTECHLTMYFVCEFIKK 275 >gi|61699226 pulmonary surfactant-associated protein D precursor [Homo sapiens] Length = 375 Score = 134 bits (338), Expect = 6e-32 Identities = 82/248 (33%), Positives = 114/248 (45%), Gaps = 5/248 (2%) Query: 21 PSGHPQPAGDDACSVQILVPGLKGDAGEKGDKGAPGRPGRVGPTGEKGDMGDKGQKGSVG 80 P G P P G+ ++ PG++G AG +G G G G G G G+ G G G++G Sbjct: 131 PQGKPGPKGEAGPKGEVGAPGMQGSAGARGLAGPKGERGVPGERGVPGNTGAAGSAGAMG 190 Query: 81 RHGKIGPIGSKGEKGDSGDIGPPGPNGEPGLPCECSQLRKAIGEMDNQVSQLTSELKFIK 140 G G G G KGD G G G GE GLP + + LR+ + + QV L + K Sbjct: 191 PQGSPGARGPPGLKGDKGIPGDKGAKGESGLP-DVASLRQQVEALQGQVQHLQAAFSQYK 249 Query: 141 NA--VAGVRETESKIYLLVKEEKRYADAQLSCQGRGGTLSMPKDEAANGLMAAYLAQAGL 198 + KI+ K + +AQL C GG L+ P+ A N + L A Sbjct: 250 KVELFPNGQSVGEKIFKTAGFVKPFTEAQLLCTQAGGQLASPRSAAENAAL-QQLVVAKN 308 Query: 199 ARVFIGINDLEKEGAFVYSDHSPMRTFNKWRSGEPNNAYDEEDCVEMVASGGWNDVACHT 258 F+ + D + EG F Y + ++ W GEPN+ EDCVE+ +G WND AC Sbjct: 309 EAAFLSMTDSKTEGKFTYPTGESL-VYSNWAPGEPNDDGGSEDCVEIFTNGKWNDRACGE 367 Query: 259 TMYFMCEF 266 +CEF Sbjct: 368 KRLVVCEF 375 Score = 70.5 bits (171), Expect = 1e-12 Identities = 36/71 (50%), Positives = 39/71 (54%), Gaps = 6/71 (8%) Query: 48 EKGDKGAPGRPGRVGPTGEKGDMGDKGQKGSVGRHGKIGPIGSK------GEKGDSGDIG 101 E G G GR GR GP GEKGD G G G G G+ GP+G K GE G GD G Sbjct: 44 ESGLPGRDGRDGREGPRGEKGDPGLPGAAGQAGMPGQAGPVGPKGDNGSVGEPGPKGDTG 103 Query: 102 PPGPNGEPGLP 112 P GP G PG+P Sbjct: 104 PSGPPGPPGVP 114 Score = 69.3 bits (168), Expect = 3e-12 Identities = 41/98 (41%), Positives = 48/98 (48%), Gaps = 18/98 (18%) Query: 13 SLAFLSLLPSGHPQPAGDDACSVQILVPGLKGDAGEKGDKGAPGRPGRVGPTGEKGDMGD 72 +L S + SG P G D G +G GEKGD G PG G+ G G+ G +G Sbjct: 36 TLVMCSSVESGLPGRDGRD---------GREGPRGEKGDPGLPGAAGQAGMPGQAGPVGP 86 Query: 73 KGQKGSVGRHGKIGPIGSKGEKGDSGDIGPPGPNGEPG 110 KG GSV G G KGD+G GPPGP G PG Sbjct: 87 KGDNGSV---------GEPGPKGDTGPSGPPGPPGVPG 115 Score = 69.3 bits (168), Expect = 3e-12 Identities = 37/92 (40%), Positives = 43/92 (46%) Query: 21 PSGHPQPAGDDACSVQILVPGLKGDAGEKGDKGAPGRPGRVGPTGEKGDMGDKGQKGSVG 80 P G G + Q +PG G G KGD G+ G PG G TG G G G G G Sbjct: 59 PRGEKGDPGLPGAAGQAGMPGQAGPVGPKGDNGSVGEPGPKGDTGPSGPPGPPGVPGPAG 118 Query: 81 RHGKIGPIGSKGEKGDSGDIGPPGPNGEPGLP 112 R G +G G+ G +G G G GP GE G P Sbjct: 119 REGPLGKQGNIGPQGKPGPKGEAGPKGEVGAP 150 Score = 28.5 bits (62), Expect = 6.5 Identities = 13/29 (44%), Positives = 14/29 (48%) Query: 89 GSKGEKGDSGDIGPPGPNGEPGLPCECSQ 117 G G G G GP G G+PGLP Q Sbjct: 46 GLPGRDGRDGREGPRGEKGDPGLPGAAGQ 74 >gi|4557739 soluble mannose-binding lectin precursor [Homo sapiens] Length = 248 Score = 111 bits (278), Expect = 6e-25 Identities = 73/226 (32%), Positives = 108/226 (47%), Gaps = 30/226 (13%) Query: 50 GDKGAPGRPGRVGPTGEKGDMGDKGQKGSVGRHGKIGPIGSKGEKGDSGDIGPPGPNGEP 109 G G PG+ GR G GEKG+ G +G +G G GK+GP G G SG GP G G+P Sbjct: 42 GINGFPGKDGRDGTKGEKGEPG-QGLRGLQGPPGKLGP---PGNPGPSGSPGPKGQKGDP 97 Query: 110 GLPCECSQLRKAIGEMDNQVSQLTSELKFIKNAVAGVR---------ETESKIYLLVKEE 160 G D S SE K ++ +A ++ + +K +L E Sbjct: 98 GK------------SPDGDSSLAASERKALQTEMARIKKWLTFSLGKQVGNKFFLTNGEI 145 Query: 161 KRYADAQLSCQGRGGTLSMPKDEAANGLMAAYLAQAGLARVFIGINDLEKEGAFVYSDHS 220 + + C +++ P++ A NG + + + F+GI D + EG FV + Sbjct: 146 MTFEKVKALCVKFQASVATPRNAAENGAIQNLIKE----EAFLGITDEKTEGQFVDLTGN 201 Query: 221 PMRTFNKWRSGEPNNAYDEEDCVEMVASGGWNDVACHTTMYFMCEF 266 + T+ W GEPNNA +EDCV ++ +G WNDV C T+ +CEF Sbjct: 202 RL-TYTNWNEGEPNNAGSDEDCVLLLKNGQWNDVPCSTSHLAVCEF 246 >gi|148886696 surfactant protein A2 [Homo sapiens] Length = 248 Score = 107 bits (267), Expect = 1e-23 Identities = 73/244 (29%), Positives = 115/244 (47%), Gaps = 15/244 (6%) Query: 28 AGDDACSVQILVPGLKGDAGEKGDKGAPGRPGRVGPTGEKGDMGDKGQKGSV----GRHG 83 A AC V+ + G G G G G PGR GR G G+ G G G G G +G Sbjct: 15 ASGAACEVKDVCVGSPGIPGTPGSHGLPGRDGRDGVKGDPGPPGPMGPPGETPCPPGNNG 74 Query: 84 KIGPIGSKGEKGDSGDIGPPGPNGEPGLPCEC-SQLRKAIGEMDNQVSQLTSELKFIKNA 142 G G GE+G+ G+ G GP PGLP +L+ + + +Q+ Q L ++ + Sbjct: 75 LPGAPGVPGERGEKGEAGERGP---PGLPAHLDEELQATLHDFRHQILQTRGALS-LQGS 130 Query: 143 VAGVRETESKIYLLVKEEKRYADAQLSCQGRGGTLSMPKDEAANGLMAAYLAQAGLARVF 202 + V E K++ + + Q +C GG +++P++ N +A+++ + + Sbjct: 131 IMTVGE---KVFSSNGQSITFDAIQEACARAGGRIAVPRNPEENEAIASFVKKYN-TYAY 186 Query: 203 IGINDLEKEGAFVYSDHSPMRTFNKWRSGEPNNAYDEEDCVEMVASGGWNDVACHTTMYF 262 +G+ + G F YSD +P+ + W GEP +E CVEM G WND C + Sbjct: 187 VGLTEGPSPGDFRYSDGTPV-NYTNWYRGEPAGR-GKEQCVEMYTDGQWNDRNCLYSRLT 244 Query: 263 MCEF 266 +CEF Sbjct: 245 ICEF 248 Score = 33.5 bits (75), Expect = 0.20 Identities = 15/41 (36%), Positives = 22/41 (53%) Query: 21 PSGHPQPAGDDACSVQILVPGLKGDAGEKGDKGAPGRPGRV 61 P P P G++ VPG +G+ GE G++G PG P + Sbjct: 63 PGETPCPPGNNGLPGAPGVPGERGEKGEAGERGPPGLPAHL 103 >gi|146149162 surfactant, pulmonary-associated protein A2 [Homo sapiens] Length = 248 Score = 107 bits (267), Expect = 1e-23 Identities = 73/244 (29%), Positives = 115/244 (47%), Gaps = 15/244 (6%) Query: 28 AGDDACSVQILVPGLKGDAGEKGDKGAPGRPGRVGPTGEKGDMGDKGQKGSV----GRHG 83 A AC V+ + G G G G G PGR GR G G+ G G G G G +G Sbjct: 15 ASGAACEVKDVCVGSPGIPGTPGSHGLPGRDGRDGVKGDPGPPGPMGPPGETPCPPGNNG 74 Query: 84 KIGPIGSKGEKGDSGDIGPPGPNGEPGLPCEC-SQLRKAIGEMDNQVSQLTSELKFIKNA 142 G G GE+G+ G+ G GP PGLP +L+ + + +Q+ Q L ++ + Sbjct: 75 LPGAPGVPGERGEKGEAGERGP---PGLPAHLDEELQATLHDFRHQILQTRGALS-LQGS 130 Query: 143 VAGVRETESKIYLLVKEEKRYADAQLSCQGRGGTLSMPKDEAANGLMAAYLAQAGLARVF 202 + V E K++ + + Q +C GG +++P++ N +A+++ + + Sbjct: 131 IMTVGE---KVFSSNGQSITFDAIQEACARAGGRIAVPRNPEENEAIASFVKKYN-TYAY 186 Query: 203 IGINDLEKEGAFVYSDHSPMRTFNKWRSGEPNNAYDEEDCVEMVASGGWNDVACHTTMYF 262 +G+ + G F YSD +P+ + W GEP +E CVEM G WND C + Sbjct: 187 VGLTEGPSPGDFRYSDGTPV-NYTNWYRGEPAGR-GKEQCVEMYTDGQWNDRNCLYSRLT 244 Query: 263 MCEF 266 +CEF Sbjct: 245 ICEF 248 Score = 33.5 bits (75), Expect = 0.20 Identities = 15/41 (36%), Positives = 22/41 (53%) Query: 21 PSGHPQPAGDDACSVQILVPGLKGDAGEKGDKGAPGRPGRV 61 P P P G++ VPG +G+ GE G++G PG P + Sbjct: 63 PGETPCPPGNNGLPGAPGVPGERGEKGEAGERGPPGLPAHL 103 >gi|38888175 surfactant, pulmonary-associated protein A1B [Homo sapiens] Length = 248 Score = 105 bits (262), Expect = 4e-23 Identities = 71/241 (29%), Positives = 113/241 (46%), Gaps = 9/241 (3%) Query: 28 AGDDACSVQILVPGLKGDAGEKGDKGAPGRPGRVGPTGEKGDMGDKGQKGSVG-RHGKIG 86 A C V+ + G G G G G PGR GR G G+ G G G G + G G Sbjct: 15 ASGAVCEVKDVCVGSPGIPGTPGSHGLPGRDGRDGLKGDPGPPGPMGPPGEMPCPPGNDG 74 Query: 87 PIGSKGEKGDSGDIGPPGPNGEPGLPCEC-SQLRKAIGEMDNQVSQLTSELKFIKNAVAG 145 G+ G G+ G+ G PG G PGLP +L+ + + +Q+ Q L ++ ++ Sbjct: 75 LPGAPGIPGECGEKGEPGERGPPGLPAHLDEELQATLHDFRHQILQTRGALS-LQGSIMT 133 Query: 146 VRETESKIYLLVKEEKRYADAQLSCQGRGGTLSMPKDEAANGLMAAYLAQAGLARVFIGI 205 V E K++ + + Q +C GG +++P++ N +A+++ + ++G+ Sbjct: 134 VGE---KVFSSNGQSITFDAIQEACARAGGRIAVPRNPEENEAIASFVKKYN-TYAYVGL 189 Query: 206 NDLEKEGAFVYSDHSPMRTFNKWRSGEPNNAYDEEDCVEMVASGGWNDVACHTTMYFMCE 265 + G F YSD +P+ + W GEP +E CVEM G WND C + +CE Sbjct: 190 TEGPSPGDFRYSDGTPV-NYTNWYRGEPAGR-GKEQCVEMYTDGQWNDRNCLYSRLTICE 247 Query: 266 F 266 F Sbjct: 248 F 248 Score = 33.1 bits (74), Expect = 0.26 Identities = 15/41 (36%), Positives = 21/41 (51%) Query: 21 PSGHPQPAGDDACSVQILVPGLKGDAGEKGDKGAPGRPGRV 61 P P P G+D +PG G+ GE G++G PG P + Sbjct: 63 PGEMPCPPGNDGLPGAPGIPGECGEKGEPGERGPPGLPAHL 103 >gi|147903070 surfactant protein A1 [Homo sapiens] Length = 245 Score = 100 bits (249), Expect = 1e-21 Identities = 68/231 (29%), Positives = 108/231 (46%), Gaps = 9/231 (3%) Query: 28 AGDDACSVQILVPGLKGDAGEKGDKGAPGRPGRVGPTGEKGDMGDKGQKGSVG-RHGKIG 86 A C V+ + G G G G G PGR GR G G+ G G G G + G G Sbjct: 15 ASGAVCEVKDVCVGSPGIPGTPGSHGLPGRDGRDGLKGDPGPPGPMGPPGEMPCPPGNDG 74 Query: 87 PIGSKGEKGDSGDIGPPGPNGEPGLPCEC-SQLRKAIGEMDNQVSQLTSELKFIKNAVAG 145 G+ G G+ G+ G PG G PGLP +L+ + + +Q+ Q L ++ ++ Sbjct: 75 LPGAPGIPGECGEKGEPGERGPPGLPAHLDEELQATLHDFRHQILQTRGALS-LQGSIMT 133 Query: 146 VRETESKIYLLVKEEKRYADAQLSCQGRGGTLSMPKDEAANGLMAAYLAQAGLARVFIGI 205 V E K++ + + Q +C GG +++P++ N +A+++ + ++G+ Sbjct: 134 VGE---KVFSSNGQSITFDAIQEACARAGGRIAVPRNPEENEAIASFVKKYN-TYAYVGL 189 Query: 206 NDLEKEGAFVYSDHSPMRTFNKWRSGEPNNAYDEEDCVEMVASGGWNDVAC 256 + G F YSD +P+ + W GEP +E CVEM G WND C Sbjct: 190 TEGPSPGDFRYSDGTPV-NYTNWYRGEPAGR-GKEQCVEMYTDGQWNDRNC 238 Score = 33.1 bits (74), Expect = 0.26 Identities = 15/41 (36%), Positives = 21/41 (51%) Query: 21 PSGHPQPAGDDACSVQILVPGLKGDAGEKGDKGAPGRPGRV 61 P P P G+D +PG G+ GE G++G PG P + Sbjct: 63 PGEMPCPPGNDGLPGAPGIPGECGEKGEPGERGPPGLPAHL 103 >gi|18641360 collectin sub-family member 12 [Homo sapiens] Length = 742 Score = 100 bits (249), Expect = 1e-21 Identities = 75/265 (28%), Positives = 107/265 (40%), Gaps = 19/265 (7%) Query: 23 GHPQPAGDDACSVQILVPGLKGDAGEKGD---KGAPGRPGRVGPTGEKGDMGDKGQKGSV 79 G P PAG+ PG +G G KG KG+ G PG+ GP G GD G G G Sbjct: 476 GPPGPAGERGPIGPAGPPGERGGKGSKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKE 535 Query: 80 GRHGKIGPIGSKGEKGDSGDIGPPGPNGEPGLPCECSQLRKAIGEMDNQVSQLTSELKFI 139 G G GP G +G +G G+ G PGP G PGLP S L Sbjct: 536 GLPGPQGPPGFQGLQGTVGEPGVPGPRGLPGLPGVPGMPGPKGPPGPPGPSGAVVPLALQ 595 Query: 140 KNAVAGVRET---------ESKIYLLVKEEKRYADAQLSCQGRGGTLSMPKDEAANGLMA 190 + K Y E++ + DA+L C+ + L + Sbjct: 596 NEPTPAPEDNGCPPHWKNFTDKCYYFSVEKEIFEDAKLFCEDKSSHLVFINTREEQQWIK 655 Query: 191 AYLAQAGLARVFIGINDLEKEGAFVYSDHSPMRTFNKWRSGEPNN----AYDEEDCVEMV 246 + G +IG+ D E+E + + D + W++G+P+N EDC ++ Sbjct: 656 KQM--VGRESHWIGLTDSERENEWKWLD-GTSPDYKNWKAGQPDNWGHGHGPGEDCAGLI 712 Query: 247 ASGGWNDVACHTTMYFMCEFDKENM 271 +G WND C F+CE D+E + Sbjct: 713 YAGQWNDFQCEDVNNFICEKDRETV 737 Score = 82.0 bits (201), Expect = 5e-16 Identities = 45/98 (45%), Positives = 52/98 (53%), Gaps = 9/98 (9%) Query: 21 PSGHPQPAGDDACSVQILVPGLKGDAGEKGDKGAPGRPGR------VGPTGEKGDMGDKG 74 P G P GD PG G+ G+KG+KG PG PG +GP G G+ G KG Sbjct: 444 PPGPRGPRGDRGSQGP---PGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERGGKG 500 Query: 75 QKGSVGRHGKIGPIGSKGEKGDSGDIGPPGPNGEPGLP 112 KGS G G G G G +G SGD GPPGP G+ GLP Sbjct: 501 SKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLP 538 Score = 74.3 bits (181), Expect = 1e-13 Identities = 39/88 (44%), Positives = 44/88 (50%) Query: 23 GHPQPAGDDACSVQILVPGLKGDAGEKGDKGAPGRPGRVGPTGEKGDMGDKGQKGSVGRH 82 G P P G+ + PG G AGE+G G G PG G G KG G KG +GS G+ Sbjct: 458 GPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERGGKGSKGSQGPKGSRGSPGKP 517 Query: 83 GKIGPIGSKGEKGDSGDIGPPGPNGEPG 110 G GP G G G G G PGP G PG Sbjct: 518 GPQGPSGDPGPPGPPGKEGLPGPQGPPG 545 Score = 71.2 bits (173), Expect = 9e-13 Identities = 32/75 (42%), Positives = 41/75 (54%) Query: 38 LVPGLKGDAGEKGDKGAPGRPGRVGPTGEKGDMGDKGQKGSVGRHGKIGPIGSKGEKGDS 97 ++ G G G +GD+G+ G PG G G+KG+ G+ G G G G IGP G GE+G Sbjct: 440 ILQGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERGGK 499 Query: 98 GDIGPPGPNGEPGLP 112 G G GP G G P Sbjct: 500 GSKGSQGPKGSRGSP 514 >gi|89276751 alpha 1 type V collagen preproprotein [Homo sapiens] Length = 1838 Score = 88.6 bits (218), Expect = 5e-18 Identities = 46/92 (50%), Positives = 54/92 (58%), Gaps = 9/92 (9%) Query: 21 PSGHPQPAGDDACSVQILVPGLKGDAGEKGDKGAPGRPGRVGPTGEKGDMGDKGQKGSVG 80 P G P P G +PGLKGD+G KG+KG PG G +GP GE+G+ GD+G G Sbjct: 1457 PDGPPGPMGPPG------LPGLKGDSGPKGEKGHPGLIGLIGPPGEQGEKGDRGLPGP-- 1508 Query: 81 RHGKIGPIGSKGEKGDSGDIGPPGPNGEPGLP 112 G GP G +G G SG IGPPGP G PG P Sbjct: 1509 -QGSSGPKGEQGITGPSGPIGPPGPPGLPGPP 1539 Score = 79.7 bits (195), Expect = 2e-15 Identities = 43/96 (44%), Positives = 49/96 (51%), Gaps = 6/96 (6%) Query: 21 PSGHPQPAGDDACSVQILVPGLKGDAGEKGDKGAPGRPGRVGPTGEKGDMGDKGQKGSVG 80 PSG P G I PG G+ GE G+ G PG PG GP G KG+ G+KG+ G G Sbjct: 1259 PSGAPGADGPQGPPGGIGNPGAVGEKGEPGEAGEPGLPGEGGPPGPKGERGEKGESGPSG 1318 Query: 81 RHGKIGPIGSKGEKGDSGDIGP------PGPNGEPG 110 G GP G G+ G G GP PGP GEPG Sbjct: 1319 AAGPPGPKGPPGDDGPKGSPGPVGFPGDPGPPGEPG 1354 Score = 79.3 bits (194), Expect = 3e-15 Identities = 42/92 (45%), Positives = 46/92 (50%), Gaps = 6/92 (6%) Query: 21 PSGHPQPAGDDACSVQILVPGLKGDAGEKGDKGAPGRPGRVGPTGEKGDMGDKGQKGSVG 80 P G P PAG D PG KGD GE G G+PG G GP+G G G G G G Sbjct: 1349 PPGEPGPAGQDG------PPGDKGDDGEPGQTGSPGPTGEPGPSGPPGKRGPPGPAGPEG 1402 Query: 81 RHGKIGPIGSKGEKGDSGDIGPPGPNGEPGLP 112 R G+ G G G +G G GP GP G PG P Sbjct: 1403 RQGEKGAKGEAGLEGPPGKTGPIGPQGAPGKP 1434 Score = 77.0 bits (188), Expect = 2e-14 Identities = 45/102 (44%), Positives = 50/102 (49%), Gaps = 21/102 (20%) Query: 21 PSGHPQPAGDDACSVQILVPGLKGDAGEKGDKGAPGRPGRVGP---TGEKGDMGDKGQKG 77 P G P PAG PG +G AG G G PGRPG GP GEKG G+KG +G Sbjct: 1079 PPGPPGPAGS---------PGERGPAGAAGPIGIPGRPGPQGPPGPAGEKGAPGEKGPQG 1129 Query: 78 SVGRH---------GKIGPIGSKGEKGDSGDIGPPGPNGEPG 110 GR G GP+G GE GD G+IG PG G G Sbjct: 1130 PAGRDGLQGPVGLPGPAGPVGPPGEDGDKGEIGEPGQKGSKG 1171 Score = 76.6 bits (187), Expect = 2e-14 Identities = 40/92 (43%), Positives = 51/92 (55%), Gaps = 3/92 (3%) Query: 21 PSGHPQPAGDDACSVQILVPGLKGDAGEKGDKGAPGRPGRVGPTGEKGDMGDKGQKGSVG 80 P+G P G+D +I PG KG G+KG++G PG G GP G+ G G G+ G G Sbjct: 1145 PAGPVGPPGEDGDKGEIGEPGQKGSKGDKGEQGPPGPTGPQGPIGQPGPSGADGEPGPRG 1204 Query: 81 RHGKIGPIGSKGEKGDSGDIGPPGPNGEPGLP 112 + G G KG++G G GPPGP G GLP Sbjct: 1205 QQGL---FGQKGDEGPRGFPGPPGPVGLQGLP 1233 Score = 75.9 bits (185), Expect = 4e-14 Identities = 42/93 (45%), Positives = 51/93 (54%), Gaps = 3/93 (3%) Query: 21 PSGHPQPAGDDACSVQILVPGLKGDAGEKGDKGAPGRPGRVGPTGE---KGDMGDKGQKG 77 P G P PAG+ + G G G +G G PG G VGP GE KG++G+ GQKG Sbjct: 1109 PQGPPGPAGEKGAPGEKGPQGPAGRDGLQGPVGLPGPAGPVGPPGEDGDKGEIGEPGQKG 1168 Query: 78 SVGRHGKIGPIGSKGEKGDSGDIGPPGPNGEPG 110 S G G+ GP G G +G G GP G +GEPG Sbjct: 1169 SKGDKGEQGPPGPTGPQGPIGQPGPSGADGEPG 1201 Score = 75.9 bits (185), Expect = 4e-14 Identities = 42/100 (42%), Positives = 49/100 (49%), Gaps = 12/100 (12%) Query: 23 GHPQPAGDDACSVQILVPGLKGDAGEKGDKGAPGRPGRVGPTGEKGDMGDKGQKGSV--- 79 G P AG+ + PG KG+ GEKG+ G G G GP G GD G KG G V Sbjct: 1285 GEPGEAGEPGLPGEGGPPGPKGERGEKGESGPSGAAGPPGPKGPPGDDGPKGSPGPVGFP 1344 Query: 80 ---------GRHGKIGPIGSKGEKGDSGDIGPPGPNGEPG 110 G G+ GP G KG+ G+ G G PGP GEPG Sbjct: 1345 GDPGPPGEPGPAGQDGPPGDKGDDGEPGQTGSPGPTGEPG 1384 Score = 75.9 bits (185), Expect = 4e-14 Identities = 48/109 (44%), Positives = 52/109 (47%), Gaps = 12/109 (11%) Query: 21 PSGHPQPAGDDACSVQILVPGL------KGDAGEKGDKGAPGRPGRVGPTGEKGDMGDKG 74 P G P GD + PGL G+ GEKGD+G PG G GP GE+G G G Sbjct: 1466 PPGLPGLKGDSGPKGEKGHPGLIGLIGPPGEQGEKGDRGLPGPQGSSGPKGEQGITGPSG 1525 Query: 75 QKGSVGRHGKIGPIGSKGEKGDSGDIGP------PGPNGEPGLPCECSQ 117 G G G GP G KG KG SG GP PGP G PG P E Q Sbjct: 1526 PIGPPGPPGLPGPPGPKGAKGSSGPTGPKGEAGHPGPPGPPGPPGEVIQ 1574 Score = 74.3 bits (181), Expect = 1e-13 Identities = 42/99 (42%), Positives = 51/99 (51%), Gaps = 9/99 (9%) Query: 21 PSGHPQPAGDDACSVQILVPGLKGDAGEKGDKGAPGRPGRVGPTGEKGDMGDKGQKGSVG 80 P+G P P G ++ VPGL G G +G KG+ G PG G GEKG G G+ G G Sbjct: 851 PNGDPGPLGPPGEKGKLGVPGLPGYPGRQGPKGSIGFPGFPGANGEKGGRGTPGKPGPRG 910 Query: 81 RHGKIGPIGSK---------GEKGDSGDIGPPGPNGEPG 110 + G GP G + G KG+SG GP GP GE G Sbjct: 911 QRGPTGPRGERGPRGITGKPGPKGNSGGDGPAGPPGERG 949 Score = 74.3 bits (181), Expect = 1e-13 Identities = 40/90 (44%), Positives = 42/90 (46%), Gaps = 9/90 (10%) Query: 21 PSGHPQPAGDDACSVQILVPGLKGDAGEKGDKGAPGRPGRVGPTGEKGDMGDKGQKGSVG 80 P G P GDD G KG G G G PG PG GP G+ G GDKG G G Sbjct: 1322 PPGPKGPPGDD---------GPKGSPGPVGFPGDPGPPGEPGPAGQDGPPGDKGDDGEPG 1372 Query: 81 RHGKIGPIGSKGEKGDSGDIGPPGPNGEPG 110 + G GP G G G G GPPGP G G Sbjct: 1373 QTGSPGPTGEPGPSGPPGKRGPPGPAGPEG 1402 Score = 73.9 bits (180), Expect = 1e-13 Identities = 43/97 (44%), Positives = 50/97 (51%), Gaps = 9/97 (9%) Query: 21 PSGHPQPAGDDACSVQILVPGLKGDAGEKGDKGAPGRPGRV---GPTGEKGDMGDKGQ-- 75 P G P P G D PG +G+ G +G G PG PG V GPTGE G MG++G Sbjct: 962 PKGPPGPPGKDGLPGH---PGQRGETGFQGKTGPPGPPGVVGPQGPTGETGPMGERGHPG 1018 Query: 76 -KGSVGRHGKIGPIGSKGEKGDSGDIGPPGPNGEPGL 111 G G G G G +G KGD G G PG +G PGL Sbjct: 1019 PPGPPGEQGLPGLAGKEGTKGDPGPAGLPGKDGPPGL 1055 Score = 73.9 bits (180), Expect = 1e-13 Identities = 44/114 (38%), Positives = 52/114 (45%), Gaps = 24/114 (21%) Query: 21 PSGHPQPAGDDACSVQILVPGLKGDAGEKGDKGAPGRPGRVGPTG--------------- 65 P G P P G PG KG+ G+ G G PG PG GP+G Sbjct: 1217 PRGFPGPPGPVGLQGLPGPPGEKGETGDVGQMGPPGPPGPRGPSGAPGADGPQGPPGGIG 1276 Query: 66 ------EKGDMGDKGQKGSVGRHGKIGPIGSKGEKGDSGD---IGPPGPNGEPG 110 EKG+ G+ G+ G G G GP G +GEKG+SG GPPGP G PG Sbjct: 1277 NPGAVGEKGEPGEAGEPGLPGEGGPPGPKGERGEKGESGPSGAAGPPGPKGPPG 1330 Score = 73.6 bits (179), Expect = 2e-13 Identities = 44/103 (42%), Positives = 52/103 (50%), Gaps = 18/103 (17%) Query: 23 GHPQPAGDDACSVQILVPGLKGDAGEKGDKGAPGRPGRVGPTGEKGDMGDKGQ------- 75 GHP P G + +PGL G G KGD G G PG+ GP G +G GD+G Sbjct: 1015 GHPGPPGPPG---EQGLPGLAGKEGTKGDPGPAGLPGKDGPPGLRGFPGDRGLPGPVGAL 1071 Query: 76 --KGSVGRHGKIGPIGSKGEKGDSGDIGP------PGPNGEPG 110 KG+ G G GP GS GE+G +G GP PGP G PG Sbjct: 1072 GLKGNEGPPGPPGPAGSPGERGPAGAAGPIGIPGRPGPQGPPG 1114 Score = 73.2 bits (178), Expect = 2e-13 Identities = 39/92 (42%), Positives = 47/92 (51%), Gaps = 6/92 (6%) Query: 21 PSGHPQPAGDDACSVQILVPGLKGDAGEKGDKGAPGRPGRVGPTGEKGDMGDKGQKGSVG 80 P G+P P G G++G G KG+KG G PG G G KGD G+ G G G Sbjct: 785 PIGYPGPRGVKGAD------GIRGLKGTKGEKGEDGFPGFKGDMGIKGDRGEIGPPGPRG 838 Query: 81 RHGKIGPIGSKGEKGDSGDIGPPGPNGEPGLP 112 G GP G G GD G +GPPG G+ G+P Sbjct: 839 EDGPEGPKGRGGPNGDPGPLGPPGEKGKLGVP 870 Score = 73.2 bits (178), Expect = 2e-13 Identities = 39/91 (42%), Positives = 44/91 (48%) Query: 21 PSGHPQPAGDDACSVQILVPGLKGDAGEKGDKGAPGRPGRVGPTGEKGDMGDKGQKGSVG 80 P+G P G + PG KG G G G PG PG+ G TG +G G G G VG Sbjct: 941 PAGPPGERGPNGPQGPTGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPPGVVG 1000 Query: 81 RHGKIGPIGSKGEKGDSGDIGPPGPNGEPGL 111 G G G GE+G G GPPG G PGL Sbjct: 1001 PQGPTGETGPMGERGHPGPPGPPGEQGLPGL 1031 Score = 73.2 bits (178), Expect = 2e-13 Identities = 46/112 (41%), Positives = 53/112 (47%), Gaps = 18/112 (16%) Query: 21 PSGHPQPAGDDACSVQILVPGLKGDAGEKGDKGAPGRPGRV------GPTGEKGDMGDKG 74 P G P P+G D GL G G++G +G PG PG V GP GEKG+ GD G Sbjct: 1187 PIGQPGPSGADGEPGPRGQQGLFGQKGDEGPRGFPGPPGPVGLQGLPGPPGEKGETGDVG 1246 Query: 75 QKGSVGRHGKIGPIGSKGEKGDS------------GDIGPPGPNGEPGLPCE 114 Q G G G GP G+ G G G+ G PG GEPGLP E Sbjct: 1247 QMGPPGPPGPRGPSGAPGADGPQGPPGGIGNPGAVGEKGEPGEAGEPGLPGE 1298 Score = 73.2 bits (178), Expect = 2e-13 Identities = 40/90 (44%), Positives = 45/90 (50%), Gaps = 3/90 (3%) Query: 21 PSGHPQPAGDDACSVQILVPGLKGDAGEKGDKGAPGRPGRVGPTGEKGDMGDKGQKGSVG 80 P G P G D +PG G+ G G G G PG +GP G G GD G KG G Sbjct: 1427 PQGAPGKPGPDGLRG---IPGPVGEQGLPGSPGPDGPPGPMGPPGLPGLKGDSGPKGEKG 1483 Query: 81 RHGKIGPIGSKGEKGDSGDIGPPGPNGEPG 110 G IG IG GE+G+ GD G PGP G G Sbjct: 1484 HPGLIGLIGPPGEQGEKGDRGLPGPQGSSG 1513 Score = 72.8 bits (177), Expect = 3e-13 Identities = 42/99 (42%), Positives = 48/99 (48%), Gaps = 9/99 (9%) Query: 23 GHPQPAGDDACSVQILVPGLKGDAGEKGDKGAPGRP------GRVGPTGEKGDMGDKGQK 76 G P G I PG G GEKG +G PG+P G GP GE+G G G+ Sbjct: 871 GLPGYPGRQGPKGSIGFPGFPGANGEKGGRGTPGKPGPRGQRGPTGPRGERGPRGITGKP 930 Query: 77 GSVGRHGKIGPIGSKGEKGDSGDIGP---PGPNGEPGLP 112 G G G GP G GE+G +G GP PGP G PG P Sbjct: 931 GPKGNSGGDGPAGPPGERGPNGPQGPTGFPGPKGPPGPP 969 Score = 72.0 bits (175), Expect = 5e-13 Identities = 45/104 (43%), Positives = 53/104 (50%), Gaps = 12/104 (11%) Query: 21 PSGHPQPAGDDA---CSVQILVPGLKGDAGEKGDKGAPGRPGRVGPTGEKGDMGDKGQKG 77 PSG P P GDD ++ GL G+ G +G G G PG GP G G G G KG Sbjct: 650 PSGPPGPPGDDGERGDDGEVGPRGLPGEPGPRGLLGPKGPPGPPGPPGVTGMDGQPGPKG 709 Query: 78 SVGRHGKIGPIGSKGE------KGDSGDIGPP---GPNGEPGLP 112 +VG G+ GP G +G G G IGPP GP G+PGLP Sbjct: 710 NVGPQGEPGPPGQQGNPGAQGLPGPQGAIGPPGEKGPLGKPGLP 753 Score = 72.0 bits (175), Expect = 5e-13 Identities = 39/77 (50%), Positives = 47/77 (61%), Gaps = 6/77 (7%) Query: 40 PGLKGDAGEKGDKGAPGRPGRVG---PTGEKGDMGDKGQKGSVGRHGKIGPIGSKGE--- 93 PG +G GEKG +G PG G +G P G KG G +G KG+ G G+ G G KG+ Sbjct: 765 PGKEGPPGEKGGQGPPGPQGPIGYPGPRGVKGADGIRGLKGTKGEKGEDGFPGFKGDMGI 824 Query: 94 KGDSGDIGPPGPNGEPG 110 KGD G+IGPPGP GE G Sbjct: 825 KGDRGEIGPPGPRGEDG 841 Score = 71.6 bits (174), Expect = 7e-13 Identities = 42/102 (41%), Positives = 49/102 (48%), Gaps = 12/102 (11%) Query: 21 PSGHPQPAGDDACSVQILVPGL---KGDAGEKGDKGAP---------GRPGRVGPTGEKG 68 P+G P G + I +PG +G G G+KGAP GR G GP G G Sbjct: 1085 PAGSPGERGPAGAAGPIGIPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGLQGPVGLPG 1144 Query: 69 DMGDKGQKGSVGRHGKIGPIGSKGEKGDSGDIGPPGPNGEPG 110 G G G G G+IG G KG KGD G+ GPPGP G G Sbjct: 1145 PAGPVGPPGEDGDKGEIGEPGQKGSKGDKGEQGPPGPTGPQG 1186 Score = 71.2 bits (173), Expect = 9e-13 Identities = 39/104 (37%), Positives = 48/104 (46%), Gaps = 12/104 (11%) Query: 21 PSGHPQPAGDDACSVQILVPGLKGDAGEKGDKGAPGRPGR------------VGPTGEKG 68 P G P P G + PG KG+ G +G+ G PG+ G +GP GEKG Sbjct: 686 PKGPPGPPGPPGVTGMDGQPGPKGNVGPQGEPGPPGQQGNPGAQGLPGPQGAIGPPGEKG 745 Query: 69 DMGDKGQKGSVGRHGKIGPIGSKGEKGDSGDIGPPGPNGEPGLP 112 +G G G G G G G +G G+ G GPPGP G G P Sbjct: 746 PLGKPGLPGMPGADGPPGHPGKEGPPGEKGGQGPPGPQGPIGYP 789 Score = 70.1 bits (170), Expect = 2e-12 Identities = 40/103 (38%), Positives = 47/103 (45%), Gaps = 12/103 (11%) Query: 22 SGHPQPAGDDACSVQILVPGLKGDAGEKGDKGAPGRPGRVGPTGEKGDMGDKGQKGSVGR 81 +G P P G+ PG +G G +G G PG G GP G+ G G GQ+G G Sbjct: 927 TGKPGPKGNSGGDGPAGPPGERGPNGPQGPTGFPGPKGPPGPPGKDGLPGHPGQRGETGF 986 Query: 82 HGKI------------GPIGSKGEKGDSGDIGPPGPNGEPGLP 112 GK GP G G G+ G GPPGP GE GLP Sbjct: 987 QGKTGPPGPPGVVGPQGPTGETGPMGERGHPGPPGPPGEQGLP 1029 Score = 70.1 bits (170), Expect = 2e-12 Identities = 36/73 (49%), Positives = 41/73 (56%) Query: 39 VPGLKGDAGEKGDKGAPGRPGRVGPTGEKGDMGDKGQKGSVGRHGKIGPIGSKGEKGDSG 98 +PG G G KG++G PG PG G GE+G G G G GR G GP G GEKG G Sbjct: 1064 LPGPVGALGLKGNEGPPGPPGPAGSPGERGPAGAAGPIGIPGRPGPQGPPGPAGEKGAPG 1123 Query: 99 DIGPPGPNGEPGL 111 + GP GP G GL Sbjct: 1124 EKGPQGPAGRDGL 1136 Score = 69.7 bits (169), Expect = 3e-12 Identities = 43/108 (39%), Positives = 54/108 (50%), Gaps = 11/108 (10%) Query: 23 GHPQ------PAGDDACSVQILVPGLKGDAGEKGDKGAPGRPGRVGPTGEKGDMGDKGQK 76 GHP P G+ +PG +G +G KG++G G G +GP G G G G K Sbjct: 1483 GHPGLIGLIGPPGEQGEKGDRGLPGPQGSSGPKGEQGITGPSGPIGPPGPPGLPGPPGPK 1542 Query: 77 GSVGRHGKIGPIGSKGEKGDSGDIGPPGPNGE--PGLPCECSQLRKAI 122 G+ G GP G KGE G G GPPGP GE LP + S+ R+ I Sbjct: 1543 GA---KGSSGPTGPKGEAGHPGPPGPPGPPGEVIQPLPIQASRTRRNI 1587 Score = 68.9 bits (167), Expect = 4e-12 Identities = 40/94 (42%), Positives = 49/94 (52%), Gaps = 18/94 (19%) Query: 23 GHPQPAGDDACSVQILVPGLKGDAGEKGDKGAPGRPGRVGPTGEKGD------MGDKGQK 76 G P PAG PG +G AG G A G PG+ GP G++G G+KG + Sbjct: 598 GPPGPAGK---------PGRRGRAGSDG---ARGMPGQTGPKGDRGFDGLAGLPGEKGHR 645 Query: 77 GSVGRHGKIGPIGSKGEKGDSGDIGPPGPNGEPG 110 G G G GP G GE+GD G++GP G GEPG Sbjct: 646 GDPGPSGPPGPPGDDGERGDDGEVGPRGLPGEPG 679 Score = 68.6 bits (166), Expect = 6e-12 Identities = 35/72 (48%), Positives = 40/72 (55%) Query: 41 GLKGDAGEKGDKGAPGRPGRVGPTGEKGDMGDKGQKGSVGRHGKIGPIGSKGEKGDSGDI 100 GL G GEKG +G PG G GP G+ G+ GD G+ G G G+ GP G G KG G Sbjct: 634 GLAGLPGEKGHRGDPGPSGPPGPPGDDGERGDDGEVGPRGLPGEPGPRGLLGPKGPPGPP 693 Query: 101 GPPGPNGEPGLP 112 GPPG G G P Sbjct: 694 GPPGVTGMDGQP 705 Score = 67.8 bits (164), Expect = 1e-11 Identities = 39/89 (43%), Positives = 46/89 (51%), Gaps = 6/89 (6%) Query: 23 GHPQPAGDDACSVQILVPGLKGDAGEKGDKGAPGRPGRVGPTGEKGDMGDKGQKGSVGRH 82 G PAG D + GL G AG G G G G +G G+KG GDKG++G G Sbjct: 1126 GPQGPAGRDGLQGPV---GLPGPAGPVGPPGEDGDKGEIGEPGQKGSKGDKGEQGPPGPT 1182 Query: 83 GKIGPIGSKGEKGDSGDIGPPGPNGEPGL 111 G GPI G+ G SG G PGP G+ GL Sbjct: 1183 GPQGPI---GQPGPSGADGEPGPRGQQGL 1208 Score = 67.0 bits (162), Expect = 2e-11 Identities = 40/96 (41%), Positives = 45/96 (46%), Gaps = 15/96 (15%) Query: 21 PSGHPQPAGDDACSVQILVPGLKGDAGEKGDKGAPGRPGRVGPTGEKGDM------GDKG 74 P G P GD PG G GEKG G PG PG G G KG + G G Sbjct: 845 PKGRGGPNGD---------PGPLGPPGEKGKLGVPGLPGYPGRQGPKGSIGFPGFPGANG 895 Query: 75 QKGSVGRHGKIGPIGSKGEKGDSGDIGPPGPNGEPG 110 +KG G GK GP G +G G G+ GP G G+PG Sbjct: 896 EKGGRGTPGKPGPRGQRGPTGPRGERGPRGITGKPG 931 Score = 67.0 bits (162), Expect = 2e-11 Identities = 36/91 (39%), Positives = 46/91 (50%) Query: 21 PSGHPQPAGDDACSVQILVPGLKGDAGEKGDKGAPGRPGRVGPTGEKGDMGDKGQKGSVG 80 P+G G+ + + G G G G +GAPG+PG G G G +G++G GS G Sbjct: 1397 PAGPEGRQGEKGAKGEAGLEGPPGKTGPIGPQGAPGKPGPDGLRGIPGPVGEQGLPGSPG 1456 Query: 81 RHGKIGPIGSKGEKGDSGDIGPPGPNGEPGL 111 G GP+G G G GD GP G G PGL Sbjct: 1457 PDGPPGPMGPPGLPGLKGDSGPKGEKGHPGL 1487 Score = 66.6 bits (161), Expect = 2e-11 Identities = 37/90 (41%), Positives = 42/90 (46%) Query: 21 PSGHPQPAGDDACSVQILVPGLKGDAGEKGDKGAPGRPGRVGPTGEKGDMGDKGQKGSVG 80 P G P G + G +G G G G PGR GR G G +G G G KG G Sbjct: 572 PVGPPGSGGLKGEPGDVGPQGPRGVQGPPGPAGKPGRRGRAGSDGARGMPGQTGPKGDRG 631 Query: 81 RHGKIGPIGSKGEKGDSGDIGPPGPNGEPG 110 G G G KG +GD G GPPGP G+ G Sbjct: 632 FDGLAGLPGEKGHRGDPGPSGPPGPPGDDG 661 Score = 65.9 bits (159), Expect = 4e-11 Identities = 39/95 (41%), Positives = 43/95 (45%), Gaps = 3/95 (3%) Query: 21 PSGHPQP---AGDDACSVQILVPGLKGDAGEKGDKGAPGRPGRVGPTGEKGDMGDKGQKG 77 P+G P AG D G KGD G G G PG G G G G G G G Sbjct: 602 PAGKPGRRGRAGSDGARGMPGQTGPKGDRGFDGLAGLPGEKGHRGDPGPSGPPGPPGDDG 661 Query: 78 SVGRHGKIGPIGSKGEKGDSGDIGPPGPNGEPGLP 112 G G++GP G GE G G +GP GP G PG P Sbjct: 662 ERGDDGEVGPRGLPGEPGPRGLLGPKGPPGPPGPP 696 Score = 65.5 bits (158), Expect = 5e-11 Identities = 37/83 (44%), Positives = 43/83 (51%), Gaps = 12/83 (14%) Query: 40 PGLKGDAGEKGDKGAPGRPG------------RVGPTGEKGDMGDKGQKGSVGRHGKIGP 87 PG KGD G KGD+G G PG R GP G+ G +G G+KG +G G G Sbjct: 816 PGFKGDMGIKGDRGEIGPPGPRGEDGPEGPKGRGGPNGDPGPLGPPGEKGKLGVPGLPGY 875 Query: 88 IGSKGEKGDSGDIGPPGPNGEPG 110 G +G KG G G PG NGE G Sbjct: 876 PGRQGPKGSIGFPGFPGANGEKG 898 Score = 64.7 bits (156), Expect = 8e-11 Identities = 37/106 (34%), Positives = 45/106 (42%), Gaps = 18/106 (16%) Query: 23 GHPQPAGDDACSVQILVPGLKGDAGEKGDKGAPGRPGRVGPTGEKGDMGDKGQKGSVGRH 82 G P GD +PG KG G+ G G PG PG G G+ G++G +G G G Sbjct: 622 GQTGPKGDRGFDGLAGLPGEKGHRGDPGPSGPPGPPGDDGERGDDGEVGPRGLPGEPGPR 681 Query: 83 GKIGP------------------IGSKGEKGDSGDIGPPGPNGEPG 110 G +GP G KG G G+ GPPG G PG Sbjct: 682 GLLGPKGPPGPPGPPGVTGMDGQPGPKGNVGPQGEPGPPGQQGNPG 727 Score = 64.3 bits (155), Expect = 1e-10 Identities = 33/71 (46%), Positives = 38/71 (53%) Query: 41 GLKGDAGEKGDKGAPGRPGRVGPTGEKGDMGDKGQKGSVGRHGKIGPIGSKGEKGDSGDI 100 G G AG G+KG G PG GP G GD G++G G VG G G G +G G G Sbjct: 631 GFDGLAGLPGEKGHRGDPGPSGPPGPPGDDGERGDDGEVGPRGLPGEPGPRGLLGPKGPP 690 Query: 101 GPPGPNGEPGL 111 GPPGP G G+ Sbjct: 691 GPPGPPGVTGM 701 Score = 63.9 bits (154), Expect = 1e-10 Identities = 39/94 (41%), Positives = 44/94 (46%), Gaps = 18/94 (19%) Query: 23 GHPQPAGDDACSVQILVPGLKGDAGEKGDKGAPGRPGRVGPTGEKGDMGDKGQKGSVGRH 82 G P P G+D G G KG G G PG +GP GEKG +G G G GR Sbjct: 832 GPPGPRGED------------GPEGPKGRGGPNGDPGPLGPPGEKGKLGVPGLPGYPGRQ 879 Query: 83 GKIGPI------GSKGEKGDSGDIGPPGPNGEPG 110 G G I G+ GEKG G G PGP G+ G Sbjct: 880 GPKGSIGFPGFPGANGEKGGRGTPGKPGPRGQRG 913 Score = 62.8 bits (151), Expect = 3e-10 Identities = 44/125 (35%), Positives = 52/125 (41%), Gaps = 33/125 (26%) Query: 21 PSGHPQPAGDDACSVQILVPGLKGDAGEKGDKGA---PGRPGRV----------GPTGEK 67 P+G P P G + Q+ PG +G G G GA PG PG + G G K Sbjct: 476 PAGLPGPPGTMGPTGQVGDPGERGPPGRPGLPGADGLPGPPGTMLMLPFRFGGGGDAGSK 535 Query: 68 GDM--------------------GDKGQKGSVGRHGKIGPIGSKGEKGDSGDIGPPGPNG 107 G M G G G GR G +GP GS G KG+ GD+GP GP G Sbjct: 536 GPMVSAQESQAQAILQQARLALRGPAGPMGLTGRPGPVGPPGSGGLKGEPGDVGPQGPRG 595 Query: 108 EPGLP 112 G P Sbjct: 596 VQGPP 600 Score = 62.8 bits (151), Expect = 3e-10 Identities = 37/99 (37%), Positives = 44/99 (44%), Gaps = 9/99 (9%) Query: 21 PSGHPQPAGDDACSVQILVPGLKGDAGEKGDKGAPGRPGRVGPTGEKGDM---------G 71 P G P G + + G +G G G G G PG G G KGD G Sbjct: 992 PPGPPGVVGPQGPTGETGPMGERGHPGPPGPPGEQGLPGLAGKEGTKGDPGPAGLPGKDG 1051 Query: 72 DKGQKGSVGRHGKIGPIGSKGEKGDSGDIGPPGPNGEPG 110 G +G G G GP+G+ G KG+ G GPPGP G PG Sbjct: 1052 PPGLRGFPGDRGLPGPVGALGLKGNEGPPGPPGPAGSPG 1090 Score = 60.5 bits (145), Expect = 2e-09 Identities = 41/99 (41%), Positives = 47/99 (47%), Gaps = 12/99 (12%) Query: 21 PSGHPQPAGDDACSVQILVPGLKGDAG---EKGDKGAPGRPGRVGPTGEKGD------MG 71 P GHP G PG +G G +G KGA G G G GEKG+ G Sbjct: 761 PPGHPGKEGPPGEKGGQGPPGPQGPIGYPGPRGVKGADGIRGLKGTKGEKGEDGFPGFKG 820 Query: 72 DKGQKGSVGRHGKIGPIGSKGEKGDSGDIGPPGPNGEPG 110 D G KG G+IGP G +GE G G G GPNG+PG Sbjct: 821 DMGIKGD---RGEIGPPGPRGEDGPEGPKGRGGPNGDPG 856 Score = 60.1 bits (144), Expect = 2e-09 Identities = 34/91 (37%), Positives = 41/91 (45%) Query: 21 PSGHPQPAGDDACSVQILVPGLKGDAGEKGDKGAPGRPGRVGPTGEKGDMGDKGQKGSVG 80 P G P G + G G G G G G PG GP G +G G G KG G Sbjct: 908 PRGQRGPTGPRGERGPRGITGKPGPKGNSGGDGPAGPPGERGPNGPQGPTGFPGPKGPPG 967 Query: 81 RHGKIGPIGSKGEKGDSGDIGPPGPNGEPGL 111 GK G G G++G++G G GP G PG+ Sbjct: 968 PPGKDGLPGHPGQRGETGFQGKTGPPGPPGV 998 Score = 59.7 bits (143), Expect = 3e-09 Identities = 31/74 (41%), Positives = 37/74 (50%) Query: 41 GLKGDAGEKGDKGAPGRPGRVGPTGEKGDMGDKGQKGSVGRHGKIGPIGSKGEKGDSGDI 100 G G G G G G PG VGP G +G G G G GR G+ G G++G G +G Sbjct: 568 GRPGPVGPPGSGGLKGEPGDVGPQGPRGVQGPPGPAGKPGRRGRAGSDGARGMPGQTGPK 627 Query: 101 GPPGPNGEPGLPCE 114 G G +G GLP E Sbjct: 628 GDRGFDGLAGLPGE 641 Score = 57.0 bits (136), Expect = 2e-08 Identities = 36/97 (37%), Positives = 42/97 (43%), Gaps = 9/97 (9%) Query: 23 GHPQPAGDDACSVQILVPGLKGDAGEKGDKGAPGRPGRVGPTGEKGDMGDKGQKGSVGRH 82 G P P G + G +G G+ G KG G G GP GE+G G +G G G Sbjct: 904 GKPGPRGQRGPTGPRGERGPRGITGKPGPKGNSGGDGPAGPPGERGPNGPQGPTGFPGPK 963 Query: 83 GKIGP---------IGSKGEKGDSGDIGPPGPNGEPG 110 G GP G +GE G G GPPGP G G Sbjct: 964 GPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPPGVVG 1000 Score = 55.1 bits (131), Expect = 6e-08 Identities = 36/94 (38%), Positives = 46/94 (48%), Gaps = 12/94 (12%) Query: 23 GHPQPAGDDACSVQILVPGLKGDAGEKGDKGAPG--RPGRV--GPTGEKGDMGDKGQKGS 78 G PA D + G+ G GEKG KG P PG + GP G +G G G G+ Sbjct: 431 GPGMPANQDT-----IYEGIGGPRGEKGQKGEPAIIEPGMLIEGPPGPEGPAGLPGPPGT 485 Query: 79 VGRHGKIGPIGSKGEKGDSGDIGPPGPNGEPGLP 112 +G G++G GE+G G G PG +G PG P Sbjct: 486 MGPTGQVG---DPGERGPPGRPGLPGADGLPGPP 516 Score = 55.1 bits (131), Expect = 6e-08 Identities = 35/94 (37%), Positives = 44/94 (46%), Gaps = 13/94 (13%) Query: 21 PSGHPQPAGDDACSVQILVPGL--KGDAGEKGDKGAPGRPGRVGPTGEKGDMGDKGQKGS 78 P G G+ A I+ PG+ +G G +G G PG PG +GPTG+ GD G++G G Sbjct: 448 PRGEKGQKGEPA----IIEPGMLIEGPPGPEGPAGLPGPPGTMGPTGQVGDPGERGPPGR 503 Query: 79 VGRHGKIGPIGSKGEK-------GDSGDIGPPGP 105 G G G G G G GD G GP Sbjct: 504 PGLPGADGLPGPPGTMLMLPFRFGGGGDAGSKGP 537 Score = 53.5 bits (127), Expect = 2e-07 Identities = 29/67 (43%), Positives = 34/67 (50%), Gaps = 3/67 (4%) Query: 47 GEKGDKGAPGRPGRVGPTGE---KGDMGDKGQKGSVGRHGKIGPIGSKGEKGDSGDIGPP 103 G G G GRPG VGP G KG+ GD G +G G G GP G G +G +G G Sbjct: 559 GPAGPMGLTGRPGPVGPPGSGGLKGEPGDVGPQGPRGVQGPPGPAGKPGRRGRAGSDGAR 618 Query: 104 GPNGEPG 110 G G+ G Sbjct: 619 GMPGQTG 625 Score = 47.8 bits (112), Expect = 1e-05 Identities = 26/64 (40%), Positives = 30/64 (46%) Query: 49 KGDKGAPGRPGRVGPTGEKGDMGDKGQKGSVGRHGKIGPIGSKGEKGDSGDIGPPGPNGE 108 +G G G GR GP G G G KG+ G VG G G G G G G G G +G Sbjct: 558 RGPAGPMGLTGRPGPVGPPGSGGLKGEPGDVGPQGPRGVQGPPGPAGKPGRRGRAGSDGA 617 Query: 109 PGLP 112 G+P Sbjct: 618 RGMP 621 >gi|111118976 collagen, type II, alpha 1 isoform 1 precursor [Homo sapiens] Length = 1487 Score = 85.5 bits (210), Expect = 4e-17 Identities = 44/94 (46%), Positives = 52/94 (55%), Gaps = 9/94 (9%) Query: 21 PSGHPQPAGDDACSVQILVPGLKGDAGEKGDKGAPGRPGRVGPTGEKGDMGDKGQKGSVG 80 P G P PAG G G AGE+G +GA G PG VGP G G+ G G +G G Sbjct: 469 PKGEPGPAGPQ---------GAPGPAGEEGKRGARGEPGGVGPIGPPGERGAPGNRGFPG 519 Query: 81 RHGKIGPIGSKGEKGDSGDIGPPGPNGEPGLPCE 114 + G GP G+ GE+G SG GP G NG+PG P E Sbjct: 520 QDGLAGPKGAPGERGPSGLAGPKGANGDPGRPGE 553 Score = 79.0 bits (193), Expect = 4e-15 Identities = 41/92 (44%), Positives = 47/92 (51%), Gaps = 6/92 (6%) Query: 21 PSGHPQPAGDDACSVQILVPGLKGDAGEKGDKGAPGRPGRVGPTGEKGDMGDKGQKGSVG 80 P+G P G D PG KG+ GE G KG G PG GP+G G G G G G Sbjct: 832 PAGFAGPPGADG------QPGAKGEQGEAGQKGDAGAPGPQGPSGAPGPQGPTGVTGPKG 885 Query: 81 RHGKIGPIGSKGEKGDSGDIGPPGPNGEPGLP 112 G GP G+ G G +G +GPPG NG PG P Sbjct: 886 ARGAQGPPGATGFPGAAGRVGPPGSNGNPGPP 917 Score = 74.3 bits (181), Expect = 1e-13 Identities = 42/93 (45%), Positives = 51/93 (54%), Gaps = 3/93 (3%) Query: 22 SGHPQPAGDDACSVQILVPGLKGDAGEKGDKGAPGRPGRVGPTGEKGDMGDKGQKGSVGR 81 SG P AG+ PG KG+ G+ G GA G PG G G++G +G GQ+G G Sbjct: 935 SGPPGRAGEPGLQGPAGPPGEKGEPGDDGPSGAEGPPGPQGLAGQRGIVGLPGQRGERGF 994 Query: 82 HGKIGPIGSKGEK---GDSGDIGPPGPNGEPGL 111 G GP G G++ G SGD GPPGP G PGL Sbjct: 995 PGLPGPSGEPGKQGAPGASGDRGPPGPVGPPGL 1027 Score = 73.9 bits (180), Expect = 1e-13 Identities = 41/88 (46%), Positives = 46/88 (52%), Gaps = 3/88 (3%) Query: 23 GHPQPAGDDACSVQILVPGLKGDAGEKGDKGAPGRPGRVGPTGEKGDMGDKGQKGSVGRH 82 G P PAG +PG KG AG G GAPG PG GP G +G G G KG Sbjct: 399 GSPGPAGASGNPGTDGIPGAKGSAGAPGIAGAPGFPGPRGPPGPQGATGPLGPKGQT--- 455 Query: 83 GKIGPIGSKGEKGDSGDIGPPGPNGEPG 110 G+ G G KGE+G G+ GP GP G PG Sbjct: 456 GEPGIAGFKGEQGPKGEPGPAGPQGAPG 483 Score = 73.6 bits (179), Expect = 2e-13 Identities = 36/75 (48%), Positives = 44/75 (58%), Gaps = 3/75 (4%) Query: 41 GLKGDAGEKGDKGAPGRP---GRVGPTGEKGDMGDKGQKGSVGRHGKIGPIGSKGEKGDS 97 G +GD GEKG +GAPG+ G GP G G G G+KG VG G G G++G G+ Sbjct: 765 GDRGDVGEKGPEGAPGKDGGRGLTGPIGPPGPAGANGEKGEVGPPGPAGSAGARGAPGER 824 Query: 98 GDIGPPGPNGEPGLP 112 G+ GPPGP G G P Sbjct: 825 GETGPPGPAGFAGPP 839 Score = 73.2 bits (178), Expect = 2e-13 Identities = 40/96 (41%), Positives = 51/96 (53%), Gaps = 12/96 (12%) Query: 21 PSGHPQPAGDDACSVQILVPGLKGDAGEKGDKGAPGRPGRVGPTGEKGDMGDKGQKGS-- 78 P G P P+G D G +GD+G G G PG G GP GEKG+ GD G G+ Sbjct: 916 PPGPPGPSGKDGPK------GARGDSGPPGRAGEPGLQGPAGPPGEKGEPGDDGPSGAEG 969 Query: 79 ----VGRHGKIGPIGSKGEKGDSGDIGPPGPNGEPG 110 G G+ G +G G++G+ G G PGP+GEPG Sbjct: 970 PPGPQGLAGQRGIVGLPGQRGERGFPGLPGPSGEPG 1005 Score = 72.4 bits (176), Expect = 4e-13 Identities = 38/76 (50%), Positives = 41/76 (53%), Gaps = 4/76 (5%) Query: 40 PGLKGDAGEKGD----KGAPGRPGRVGPTGEKGDMGDKGQKGSVGRHGKIGPIGSKGEKG 95 PG KG GE GD G G PG GP GE+G GD+G KG G G G G G G Sbjct: 100 PGPKGQKGEPGDIKDIVGPKGPPGPQGPAGEQGPRGDRGDKGEKGAPGPRGRDGEPGTPG 159 Query: 96 DSGDIGPPGPNGEPGL 111 + G GPPGP G PGL Sbjct: 160 NPGPPGPPGPPGPPGL 175 Score = 72.4 bits (176), Expect = 4e-13 Identities = 39/90 (43%), Positives = 45/90 (50%), Gaps = 3/90 (3%) Query: 21 PSGHPQPAGDDACSVQILVPGLKGDAGEKGDKGAPGRPGRVGPTGEKGDMGDKGQKGSVG 80 P G PAG PGL+G GE+G G G G G GEKG G G+ G G Sbjct: 730 PKGASGPAGPPGAQGP---PGLQGMPGERGAAGIAGPKGDRGDVGEKGPEGAPGKDGGRG 786 Query: 81 RHGKIGPIGSKGEKGDSGDIGPPGPNGEPG 110 G IGP G G G+ G++GPPGP G G Sbjct: 787 LTGPIGPPGPAGANGEKGEVGPPGPAGSAG 816 Score = 72.4 bits (176), Expect = 4e-13 Identities = 38/91 (41%), Positives = 45/91 (49%) Query: 21 PSGHPQPAGDDACSVQILVPGLKGDAGEKGDKGAPGRPGRVGPTGEKGDMGDKGQKGSVG 80 PSG P G + Q + GL G GE+G G PG G G G G GD+G G VG Sbjct: 964 PSGAEGPPGPQGLAGQRGIVGLPGQRGERGFPGLPGPSGEPGKQGAPGASGDRGPPGPVG 1023 Query: 81 RHGKIGPIGSKGEKGDSGDIGPPGPNGEPGL 111 G GP G G +G G GPPG +G G+ Sbjct: 1024 PPGLTGPAGEPGREGSPGADGPPGRDGAAGV 1054 Score = 72.0 bits (175), Expect = 5e-13 Identities = 39/92 (42%), Positives = 45/92 (48%), Gaps = 6/92 (6%) Query: 23 GHPQPAGDDACSVQILVPGLKGDAGEKGDKGAPGRPGRVGPTGEKGDMGDKGQKGSVGRH 82 G P G D + G+KGD GE G GAPG PG G G G G +G +G G Sbjct: 1041 GADGPPGRDGAA------GVKGDRGETGAVGAPGAPGPPGSPGPAGPTGKQGDRGEAGAQ 1094 Query: 83 GKIGPIGSKGEKGDSGDIGPPGPNGEPGLPCE 114 G +GP G G +G G GP G GE G P E Sbjct: 1095 GPMGPSGPAGARGIQGPQGPRGDKGEAGEPGE 1126 Score = 71.2 bits (173), Expect = 9e-13 Identities = 36/74 (48%), Positives = 39/74 (52%), Gaps = 3/74 (4%) Query: 40 PGLKGDAGEKGDKGAPGRPGRVGPTGE---KGDMGDKGQKGSVGRHGKIGPIGSKGEKGD 96 PG G G G G PG PG GP+G+ KG GD G G G G GP G GEKG+ Sbjct: 899 PGAAGRVGPPGSNGNPGPPGPPGPSGKDGPKGARGDSGPPGRAGEPGLQGPAGPPGEKGE 958 Query: 97 SGDIGPPGPNGEPG 110 GD GP G G PG Sbjct: 959 PGDDGPSGAEGPPG 972 Score = 70.9 bits (172), Expect = 1e-12 Identities = 40/97 (41%), Positives = 52/97 (53%), Gaps = 9/97 (9%) Query: 23 GHPQPAGDDACSVQILVPGLKGDAGEKGDKGAPGR---PGRVGPTGEKGDMGDKGQKGS- 78 G P +GD + PGL G AGE G +G+PG PGR G G KGD G+ G G+ Sbjct: 1008 GAPGASGDRGPPGPVGPPGLTGPAGEPGREGSPGADGPPGRDGAAGVKGDRGETGAVGAP 1067 Query: 79 -----VGRHGKIGPIGSKGEKGDSGDIGPPGPNGEPG 110 G G GP G +G++G++G GP GP+G G Sbjct: 1068 GAPGPPGSPGPAGPTGKQGDRGEAGAQGPMGPSGPAG 1104 Score = 70.9 bits (172), Expect = 1e-12 Identities = 34/72 (47%), Positives = 41/72 (56%) Query: 41 GLKGDAGEKGDKGAPGRPGRVGPTGEKGDMGDKGQKGSVGRHGKIGPIGSKGEKGDSGDI 100 GL G G GD+GA G G GP G G +G G+ G+ G G IGP G +G G++G Sbjct: 1140 GLPGPPGPSGDQGASGPAGPSGPRGPPGPVGPSGKDGANGIPGPIGPPGPRGRSGETGPA 1199 Query: 101 GPPGPNGEPGLP 112 GPPG G PG P Sbjct: 1200 GPPGNPGPPGPP 1211 Score = 70.5 bits (171), Expect = 1e-12 Identities = 42/111 (37%), Positives = 52/111 (46%), Gaps = 21/111 (18%) Query: 23 GHPQPAGDDACSVQILVPGLKGDAGEKGD---------KGAPGRPGRVGPTGEKGDMGDK 73 GH G D + PG+KG++G G+ +G PG GR GP G G G+ Sbjct: 288 GHRGYPGLDGAKGEAGAPGVKGESGSPGENGSPGPMGPRGLPGERGRTGPAGAAGARGND 347 Query: 74 GQKGSVGRHGKIGPI---------GSKGEKGDSGDIGP---PGPNGEPGLP 112 GQ G G G +GP G+KGE G +G GP GP GEPG P Sbjct: 348 GQPGPAGPPGPVGPAGGPGFPGAPGAKGEAGPTGARGPEGAQGPRGEPGTP 398 Score = 70.5 bits (171), Expect = 1e-12 Identities = 37/78 (47%), Positives = 45/78 (57%), Gaps = 6/78 (7%) Query: 40 PGLKGDAGEKGDKGAPGR---PGRVGPTGEKGDMGDKGQKGSVGRHGK---IGPIGSKGE 93 PG G+ G+ GD+G PG PG VGP GE+G G++G G+ G G G G+ G Sbjct: 671 PGPPGEGGKPGDQGVPGEAGAPGLVGPRGERGFPGERGSPGAQGLQGPRGLPGTPGTDGP 730 Query: 94 KGDSGDIGPPGPNGEPGL 111 KG SG GPPG G PGL Sbjct: 731 KGASGPAGPPGAQGPPGL 748 Score = 70.5 bits (171), Expect = 1e-12 Identities = 41/104 (39%), Positives = 51/104 (49%), Gaps = 12/104 (11%) Query: 21 PSGHPQPAGDDACSVQILVPGLKGDAG------EKGDKGAPGRPGRVGPTGE------KG 68 P G P PAG + ++ PG G AG E+G+ G PG G GP G KG Sbjct: 790 PIGPPGPAGANGEKGEVGPPGPAGSAGARGAPGERGETGPPGPAGFAGPPGADGQPGAKG 849 Query: 69 DMGDKGQKGSVGRHGKIGPIGSKGEKGDSGDIGPPGPNGEPGLP 112 + G+ GQKG G G GP G+ G +G +G GP G G G P Sbjct: 850 EQGEAGQKGDAGAPGPQGPSGAPGPQGPTGVTGPKGARGAQGPP 893 Score = 70.5 bits (171), Expect = 1e-12 Identities = 37/82 (45%), Positives = 48/82 (58%), Gaps = 9/82 (10%) Query: 40 PGLKGDAGEKGDKGAPGR------PGRVGPTGEKGDMGDKGQKGSVGRHG---KIGPIGS 90 PGL G +GE G +GAPG PG VGP G G G+ G++GS G G + G G Sbjct: 995 PGLPGPSGEPGKQGAPGASGDRGPPGPVGPPGLTGPAGEPGREGSPGADGPPGRDGAAGV 1054 Query: 91 KGEKGDSGDIGPPGPNGEPGLP 112 KG++G++G +G PG G PG P Sbjct: 1055 KGDRGETGAVGAPGAPGPPGSP 1076 Score = 70.1 bits (170), Expect = 2e-12 Identities = 36/83 (43%), Positives = 44/83 (53%) Query: 29 GDDACSVQILVPGLKGDAGEKGDKGAPGRPGRVGPTGEKGDMGDKGQKGSVGRHGKIGPI 88 G D + PG +G +G G KGA G PGR G G G G G+ G G GK+GP Sbjct: 519 GQDGLAGPKGAPGERGPSGLAGPKGANGDPGRPGEPGLPGARGLTGRPGDAGPQGKVGPS 578 Query: 89 GSKGEKGDSGDIGPPGPNGEPGL 111 G+ GE G G GP G G+PG+ Sbjct: 579 GAPGEDGRPGPPGPQGARGQPGV 601 Score = 70.1 bits (170), Expect = 2e-12 Identities = 39/96 (40%), Positives = 46/96 (47%), Gaps = 6/96 (6%) Query: 21 PSGHPQPAGDDACSVQILVPGLKGDAGEKGDKGAPGRPGRVGPTGEKGDMGD------KG 74 P G P PAG G +G G G GA G G GP G+KG+ G+ KG Sbjct: 1072 PPGSPGPAGPTGKQGDRGEAGAQGPMGPSGPAGARGIQGPQGPRGDKGEAGEPGERGLKG 1131 Query: 75 QKGSVGRHGKIGPIGSKGEKGDSGDIGPPGPNGEPG 110 +G G G GP G G++G SG GP GP G PG Sbjct: 1132 HRGFTGLQGLPGPPGPSGDQGASGPAGPSGPRGPPG 1167 Score = 69.7 bits (169), Expect = 3e-12 Identities = 38/82 (46%), Positives = 45/82 (54%), Gaps = 9/82 (10%) Query: 40 PGLKGDAGEKGDKGAPGR------PGRVGPTGEKGDMGDKGQKGSVGRHGKIGPIGSK-- 91 PG G AGE+G++GAPG PG GP GE G GD+G G G G +GP G + Sbjct: 644 PGPAGPAGERGEQGAPGPSGFQGLPGPPGPPGEGGKPGDQGVPGEAGAPGLVGPRGERGF 703 Query: 92 -GEKGDSGDIGPPGPNGEPGLP 112 GE+G G G GP G PG P Sbjct: 704 PGERGSPGAQGLQGPRGLPGTP 725 Score = 69.7 bits (169), Expect = 3e-12 Identities = 40/91 (43%), Positives = 43/91 (47%), Gaps = 12/91 (13%) Query: 21 PSGHPQPAGDDACSVQILVPGLKGDAGEKGDKGAPGRPGRVGPTGEKGDMGDKGQKGSVG 80 PSG P P G G G KG +GA G PG G G G +G G G+ G Sbjct: 868 PSGAPGPQGPT------------GVTGPKGARGAQGPPGATGFPGAAGRVGPPGSNGNPG 915 Query: 81 RHGKIGPIGSKGEKGDSGDIGPPGPNGEPGL 111 G GP G G KG GD GPPG GEPGL Sbjct: 916 PPGPPGPSGKDGPKGARGDSGPPGRAGEPGL 946 Score = 69.3 bits (168), Expect = 3e-12 Identities = 41/99 (41%), Positives = 50/99 (50%), Gaps = 9/99 (9%) Query: 22 SGHPQPAGDDACSVQILVPGLKGDAGEKGDKGAPGRPGRVGPTGEKGDMGDKGQKGSVGR 81 +G P AG+ PGL+G G+ G+ GA G PG GP GE+G+ G G G G Sbjct: 611 NGEPGKAGEKGLPG---APGLRGLPGKDGETGAAGPPGPAGPAGERGEQGAPGPSGFQGL 667 Query: 82 HGKIGPIGSKGEKGDS---GDIGPP---GPNGEPGLPCE 114 G GP G G+ GD G+ G P GP GE G P E Sbjct: 668 PGPPGPPGEGGKPGDQGVPGEAGAPGLVGPRGERGFPGE 706 Score = 68.2 bits (165), Expect = 7e-12 Identities = 39/99 (39%), Positives = 46/99 (46%), Gaps = 9/99 (9%) Query: 21 PSGHPQPAGDDACSVQILVPGLKGDAGEKGDKGAPGR---------PGRVGPTGEKGDMG 71 P G PAG G KG+AGE G++G G PG GP+G++G G Sbjct: 1096 PMGPSGPAGARGIQGPQGPRGDKGEAGEPGERGLKGHRGFTGLQGLPGPPGPSGDQGASG 1155 Query: 72 DKGQKGSVGRHGKIGPIGSKGEKGDSGDIGPPGPNGEPG 110 G G G G +GP G G G G IGPPGP G G Sbjct: 1156 PAGPSGPRGPPGPVGPSGKDGANGIPGPIGPPGPRGRSG 1194 Score = 67.8 bits (164), Expect = 1e-11 Identities = 40/99 (40%), Positives = 48/99 (48%), Gaps = 9/99 (9%) Query: 23 GHPQPAGDDACSVQILVPGLKGDAGEKGDKGAPGRPGR---------VGPTGEKGDMGDK 73 G P GD + + GLKG G G +G PG PG GP+G +G G Sbjct: 1110 GPQGPRGDKGEAGEPGERGLKGHRGFTGLQGLPGPPGPSGDQGASGPAGPSGPRGPPGPV 1169 Query: 74 GQKGSVGRHGKIGPIGSKGEKGDSGDIGPPGPNGEPGLP 112 G G G +G GPIG G +G SG+ GP GP G PG P Sbjct: 1170 GPSGKDGANGIPGPIGPPGPRGRSGETGPAGPPGNPGPP 1208 Score = 67.4 bits (163), Expect = 1e-11 Identities = 40/99 (40%), Positives = 47/99 (47%), Gaps = 9/99 (9%) Query: 21 PSGHPQPAGDDACSVQILVPGLKGDAGEKGDKGAP---------GRPGRVGPTGEKGDMG 71 P G P G + I PG G GEKG+ G P G PG G TG G G Sbjct: 775 PEGAPGKDGGRGLTGPIGPPGPAGANGEKGEVGPPGPAGSAGARGAPGERGETGPPGPAG 834 Query: 72 DKGQKGSVGRHGKIGPIGSKGEKGDSGDIGPPGPNGEPG 110 G G+ G+ G G G G+KGD+G GP GP+G PG Sbjct: 835 FAGPPGADGQPGAKGEQGEAGQKGDAGAPGPQGPSGAPG 873 Score = 67.4 bits (163), Expect = 1e-11 Identities = 39/96 (40%), Positives = 47/96 (48%), Gaps = 6/96 (6%) Query: 21 PSGHPQPAGDDACSVQILVPGLKGDAGEKGDKGAPGR------PGRVGPTGEKGDMGDKG 74 P G GDD S PG +G AG++G G PG+ PG GP+GE G G G Sbjct: 952 PPGEKGEPGDDGPSGAEGPPGPQGLAGQRGIVGLPGQRGERGFPGLPGPSGEPGKQGAPG 1011 Query: 75 QKGSVGRHGKIGPIGSKGEKGDSGDIGPPGPNGEPG 110 G G G +GP G G G+ G G PG +G PG Sbjct: 1012 ASGDRGPPGPVGPPGLTGPAGEPGREGSPGADGPPG 1047 Score = 67.0 bits (162), Expect = 2e-11 Identities = 37/94 (39%), Positives = 45/94 (47%), Gaps = 6/94 (6%) Query: 23 GHPQPAGDDACSVQILVPGLKGDAG------EKGDKGAPGRPGRVGPTGEKGDMGDKGQK 76 G P P G +PG+KG G KG+ GAPG G G GE G G G + Sbjct: 267 GPPGPQGARGFPGTPGLPGVKGHRGYPGLDGAKGEAGAPGVKGESGSPGENGSPGPMGPR 326 Query: 77 GSVGRHGKIGPIGSKGEKGDSGDIGPPGPNGEPG 110 G G G+ GP G+ G +G+ G GP GP G G Sbjct: 327 GLPGERGRTGPAGAAGARGNDGQPGPAGPPGPVG 360 Score = 67.0 bits (162), Expect = 2e-11 Identities = 37/89 (41%), Positives = 42/89 (47%), Gaps = 9/89 (10%) Query: 23 GHPQPAGDDACSVQILVPGLKGDAGEKGDKGAPGRPGRVGPTGEKGDMGDKGQKGSVGRH 82 G P PAG PG G AG G GAPG G GPTG +G G +G +G G Sbjct: 348 GQPGPAGP---------PGPVGPAGGPGFPGAPGAKGEAGPTGARGPEGAQGPRGEPGTP 398 Query: 83 GKIGPIGSKGEKGDSGDIGPPGPNGEPGL 111 G GP G+ G G G G G G PG+ Sbjct: 399 GSPGPAGASGNPGTDGIPGAKGSAGAPGI 427 Score = 65.5 bits (158), Expect = 5e-11 Identities = 35/79 (44%), Positives = 40/79 (50%), Gaps = 9/79 (11%) Query: 41 GLKGDAGEKGDKGAPGRPG---------RVGPTGEKGDMGDKGQKGSVGRHGKIGPIGSK 91 GL G G GD G PG PG R G G +G +G G G GR G GP G++ Sbjct: 537 GLAGPKGANGDPGRPGEPGLPGARGLTGRPGDAGPQGKVGPSGAPGEDGRPGPPGPQGAR 596 Query: 92 GEKGDSGDIGPPGPNGEPG 110 G+ G G GP G NGEPG Sbjct: 597 GQPGVMGFPGPKGANGEPG 615 Score = 65.1 bits (157), Expect = 6e-11 Identities = 36/90 (40%), Positives = 42/90 (46%) Query: 21 PSGHPQPAGDDACSVQILVPGLKGDAGEKGDKGAPGRPGRVGPTGEKGDMGDKGQKGSVG 80 P G P P G + PG G+ G G +GA G PG G G KG G G G+ G Sbjct: 241 PRGPPGPPGKPGDDGEAGKPGKAGERGPPGPQGARGFPGTPGLPGVKGHRGYPGLDGAKG 300 Query: 81 RHGKIGPIGSKGEKGDSGDIGPPGPNGEPG 110 G G G G G++G GP GP G PG Sbjct: 301 EAGAPGVKGESGSPGENGSPGPMGPRGLPG 330 Score = 65.1 bits (157), Expect = 6e-11 Identities = 38/94 (40%), Positives = 46/94 (48%), Gaps = 3/94 (3%) Query: 22 SGHPQPAGDDACSVQILVPGLKGDAGEKGDKGAPGR---PGRVGPTGEKGDMGDKGQKGS 78 +G P P G + G G AG +G+ G PG PG VGP G G G G KG Sbjct: 317 NGSPGPMGPRGLPGERGRTGPAGAAGARGNDGQPGPAGPPGPVGPAGGPGFPGAPGAKGE 376 Query: 79 VGRHGKIGPIGSKGEKGDSGDIGPPGPNGEPGLP 112 G G GP G++G +G+ G G PGP G G P Sbjct: 377 AGPTGARGPEGAQGPRGEPGTPGSPGPAGASGNP 410 Score = 65.1 bits (157), Expect = 6e-11 Identities = 40/109 (36%), Positives = 49/109 (44%), Gaps = 18/109 (16%) Query: 21 PSGHPQPAGDDACSVQILVPGLKGDA------------GEKGDKGAPGRPGRVGPTGEKG 68 P+G P P G PG KG+A G +G+ G PG PG G +G G Sbjct: 352 PAGPPGPVGPAGGPGFPGAPGAKGEAGPTGARGPEGAQGPRGEPGTPGSPGPAGASGNPG 411 Query: 69 DMGDKGQKGSVGRHGKI------GPIGSKGEKGDSGDIGPPGPNGEPGL 111 G G KGS G G GP G G +G +G +GP G GEPG+ Sbjct: 412 TDGIPGAKGSAGAPGIAGAPGFPGPRGPPGPQGATGPLGPKGQTGEPGI 460 Score = 65.1 bits (157), Expect = 6e-11 Identities = 38/96 (39%), Positives = 45/96 (46%), Gaps = 6/96 (6%) Query: 23 GHPQPAGDDACSVQILVPGL------KGDAGEKGDKGAPGRPGRVGPTGEKGDMGDKGQK 76 G P P G Q V G G+ G+ G+KG PG PG G G+ G+ G G Sbjct: 585 GRPGPPGPQGARGQPGVMGFPGPKGANGEPGKAGEKGLPGAPGLRGLPGKDGETGAAGPP 644 Query: 77 GSVGRHGKIGPIGSKGEKGDSGDIGPPGPNGEPGLP 112 G G G+ G G+ G G G GPPGP GE G P Sbjct: 645 GPAGPAGERGEQGAPGPSGFQGLPGPPGPPGEGGKP 680 Score = 65.1 bits (157), Expect = 6e-11 Identities = 44/140 (31%), Positives = 59/140 (42%), Gaps = 21/140 (15%) Query: 23 GHPQPAGDDACSVQILVPGLKGDAGEKGDKGAPGRPGRVGPTGEKGDMGDKGQKGSVGRH 82 G P P+GD G G AG G +G PG G G G G G G G GR Sbjct: 1143 GPPGPSGDQ---------GASGPAGPSGPRGPPGPVGPSGKDGANGIPGPIGPPGPRGRS 1193 Query: 83 GKIGPIGSKGEKGDSGDIGPPGP----NGEPGL--------PCECSQLRKAIGEMDNQVS 130 G+ GP G G G G GPPGP + GL P + + +A G + + Sbjct: 1194 GETGPAGPPGNPGPPGPPGPPGPGIDMSAFAGLGPREKGPDPLQYMRADQAAGGLRQHDA 1253 Query: 131 QLTSELKFIKNAVAGVRETE 150 ++ + LK + N + +R E Sbjct: 1254 EVDATLKSLNNQIESIRSPE 1273 Score = 64.7 bits (156), Expect = 8e-11 Identities = 37/90 (41%), Positives = 44/90 (48%) Query: 21 PSGHPQPAGDDACSVQILVPGLKGDAGEKGDKGAPGRPGRVGPTGEKGDMGDKGQKGSVG 80 P G P GDD + + G +G G +G +G PG PG G G +G G G KG G Sbjct: 244 PPGPPGKPGDDGEAGKPGKAGERGPPGPQGARGFPGTPGLPGVKGHRGYPGLDGAKGEAG 303 Query: 81 RHGKIGPIGSKGEKGDSGDIGPPGPNGEPG 110 G G GS GE G G +GP G GE G Sbjct: 304 APGVKGESGSPGENGSPGPMGPRGLPGERG 333 Score = 64.3 bits (155), Expect = 1e-10 Identities = 36/92 (39%), Positives = 44/92 (47%), Gaps = 6/92 (6%) Query: 21 PSGHPQPAGDDACSVQILVPGLKGDAGEKGDKGAPGRPGRVGPTGEKGDMGDKGQKGSVG 80 P G P PAG G +G+ GE G+ G G G GP G G GD G+ G G Sbjct: 208 PRGPPGPAGAPGPQ------GFQGNPGEPGEPGVSGPMGPRGPPGPPGKPGDDGEAGKPG 261 Query: 81 RHGKIGPIGSKGEKGDSGDIGPPGPNGEPGLP 112 + G+ GP G +G +G G G PG G G P Sbjct: 262 KAGERGPPGPQGARGFPGTPGLPGVKGHRGYP 293 Score = 64.3 bits (155), Expect = 1e-10 Identities = 39/108 (36%), Positives = 45/108 (41%), Gaps = 18/108 (16%) Query: 21 PSGHPQPAGDDACSVQILVPGLKGDAGEKG---------------DKGAPGRPGRVGPTG 65 P G GD + PGL G GE+G +G PG PG GP G Sbjct: 673 PPGEGGKPGDQGVPGEAGAPGLVGPRGERGFPGERGSPGAQGLQGPRGLPGTPGTDGPKG 732 Query: 66 EKGDMGDKGQKGSVGRH---GKIGPIGSKGEKGDSGDIGPPGPNGEPG 110 G G G +G G G+ G G G KGD GD+G GP G PG Sbjct: 733 ASGPAGPPGAQGPPGLQGMPGERGAAGIAGPKGDRGDVGEKGPEGAPG 780 Score = 63.2 bits (152), Expect = 2e-10 Identities = 35/97 (36%), Positives = 47/97 (48%), Gaps = 6/97 (6%) Query: 16 FLSLLPSGHPQPAGDDACSVQILVPGLKGDAGEKGDKGAPGRPGRVGPTGEKGDMGDKGQ 75 F + + G + AG V ++G G G +G PG G GP G +G+ G+ G+ Sbjct: 179 FAAQMAGGFDEKAGGAQLGV------MQGPMGPMGPRGPPGPAGAPGPQGFQGNPGEPGE 232 Query: 76 KGSVGRHGKIGPIGSKGEKGDSGDIGPPGPNGEPGLP 112 G G G GP G G+ GD G+ G PG GE G P Sbjct: 233 PGVSGPMGPRGPPGPPGKPGDDGEAGKPGKAGERGPP 269 Score = 62.4 bits (150), Expect = 4e-10 Identities = 36/92 (39%), Positives = 45/92 (48%) Query: 21 PSGHPQPAGDDACSVQILVPGLKGDAGEKGDKGAPGRPGRVGPTGEKGDMGDKGQKGSVG 80 PSG P G + + PGL G G G G G G+VGP+G G+ G G G G Sbjct: 535 PSGLAGPKGANGDPGRPGEPGLPGARGLTGRPGDAGPQGKVGPSGAPGEDGRPGPPGPQG 594 Query: 81 RHGKIGPIGSKGEKGDSGDIGPPGPNGEPGLP 112 G+ G +G G KG +G+ G G G PG P Sbjct: 595 ARGQPGVMGFPGPKGANGEPGKAGEKGLPGAP 626 Score = 62.0 bits (149), Expect = 5e-10 Identities = 35/89 (39%), Positives = 44/89 (49%) Query: 22 SGHPQPAGDDACSVQILVPGLKGDAGEKGDKGAPGRPGRVGPTGEKGDMGDKGQKGSVGR 81 +G P AG PG G G G +GA G+PG +G G KG G+ G+ G G Sbjct: 563 TGRPGDAGPQGKVGPSGAPGEDGRPGPPGPQGARGQPGVMGFPGPKGANGEPGKAGEKGL 622 Query: 82 HGKIGPIGSKGEKGDSGDIGPPGPNGEPG 110 G G G G+ G++G GPPGP G G Sbjct: 623 PGAPGLRGLPGKDGETGAAGPPGPAGPAG 651 Score = 60.8 bits (146), Expect = 1e-09 Identities = 37/107 (34%), Positives = 47/107 (43%), Gaps = 15/107 (14%) Query: 23 GHPQPAGDDACSVQILVPGLKGDAGEKGDKGAPGRPGRVGPTGEKGDMGDKGQKGSV--- 79 G+P G+ S + G G G+ GD G G+PG+ G G G G +G G+ Sbjct: 225 GNPGEPGEPGVSGPMGPRGPPGPPGKPGDDGEAGKPGKAGERGPPGPQGARGFPGTPGLP 284 Query: 80 ------------GRHGKIGPIGSKGEKGDSGDIGPPGPNGEPGLPCE 114 G G+ G G KGE G G+ G PGP G GLP E Sbjct: 285 GVKGHRGYPGLDGAKGEAGAPGVKGESGSPGENGSPGPMGPRGLPGE 331 Score = 60.8 bits (146), Expect = 1e-09 Identities = 32/72 (44%), Positives = 35/72 (48%) Query: 41 GLKGDAGEKGDKGAPGRPGRVGPTGEKGDMGDKGQKGSVGRHGKIGPIGSKGEKGDSGDI 100 G G G G KGAPG G G G KG GD G+ G G G G G G+ G G + Sbjct: 516 GFPGQDGLAGPKGAPGERGPSGLAGPKGANGDPGRPGEPGLPGARGLTGRPGDAGPQGKV 575 Query: 101 GPPGPNGEPGLP 112 GP G GE G P Sbjct: 576 GPSGAPGEDGRP 587 Score = 60.1 bits (144), Expect = 2e-09 Identities = 42/122 (34%), Positives = 48/122 (39%), Gaps = 30/122 (24%) Query: 21 PSGHPQPAGDDACSVQILVPGLKGDAGEKGDKGAPGRPGRVGPTG--------------- 65 P+G P GD + PG +G GE G G PG PG GP G Sbjct: 127 PAGEQGPRGDRGDKGEKGAPGPRGRDGEPGTPGNPGPPGPPGPPGPPGLGGNFAAQMAGG 186 Query: 66 --EK-------------GDMGDKGQKGSVGRHGKIGPIGSKGEKGDSGDIGPPGPNGEPG 110 EK G MG +G G G G G G+ GE G+ G GP GP G PG Sbjct: 187 FDEKAGGAQLGVMQGPMGPMGPRGPPGPAGAPGPQGFQGNPGEPGEPGVSGPMGPRGPPG 246 Query: 111 LP 112 P Sbjct: 247 PP 248 Score = 59.3 bits (142), Expect = 3e-09 Identities = 35/93 (37%), Positives = 48/93 (51%), Gaps = 6/93 (6%) Query: 21 PSGHPQPAGDDACSVQILVPGLKGDAGEKGDKGAPGRPGRVGPTGEK---GDMGDKGQKG 77 P G P P G + + G G+ G G KG G G GP G + G G++G++G Sbjct: 436 PRGPPGPQG---ATGPLGPKGQTGEPGIAGFKGEQGPKGEPGPAGPQGAPGPAGEEGKRG 492 Query: 78 SVGRHGKIGPIGSKGEKGDSGDIGPPGPNGEPG 110 + G G +GPIG GE+G G+ G PG +G G Sbjct: 493 ARGEPGGVGPIGPPGERGAPGNRGFPGQDGLAG 525 Score = 58.5 bits (140), Expect = 6e-09 Identities = 30/63 (47%), Positives = 37/63 (58%), Gaps = 4/63 (6%) Query: 54 APGRPGRVGPTGEKGD----MGDKGQKGSVGRHGKIGPIGSKGEKGDSGDIGPPGPNGEP 109 A G+PG G GE GD +G KG G G G+ GP G +G+KG+ G GP G +GEP Sbjct: 96 ASGQPGPKGQKGEPGDIKDIVGPKGPPGPQGPAGEQGPRGDRGDKGEKGAPGPRGRDGEP 155 Query: 110 GLP 112 G P Sbjct: 156 GTP 158 Score = 57.8 bits (138), Expect = 1e-08 Identities = 35/91 (38%), Positives = 44/91 (48%), Gaps = 3/91 (3%) Query: 22 SGHPQPAGDDACSVQILVPGLKGDAGEKGDKGAPGRPGRVGPTGEKGDMGDKGQKGSVGR 81 +G P G+ + G GDAG +G G G PG G G G G +GQ G +G Sbjct: 545 NGDPGRPGEPGLPGARGLTGRPGDAGPQGKVGPSGAPGEDGRPGPPGPQGARGQPGVMGF 604 Query: 82 HGKIGPIGSKGEKGDSGDIGPPGPNGEPGLP 112 GP G+ GE G +G+ G PG G GLP Sbjct: 605 P---GPKGANGEPGKAGEKGLPGAPGLRGLP 632 Score = 55.1 bits (131), Expect = 6e-08 Identities = 34/88 (38%), Positives = 40/88 (45%), Gaps = 3/88 (3%) Query: 23 GHPQPAGDDACSVQILVPGLKGDAGEKGDKGAPGRPGRVGPTGEKGDMGDKGQKGSVGRH 82 G P P G+ VPG G G G +G G PG G G +G G +G G+ G Sbjct: 669 GPPGPPGEGGKPGDQGVPGEAGAPGLVGPRGERGFPGERGSPGAQGLQGPRGLPGTPGTD 728 Query: 83 GKIGPIGSKGEKGDSGDIGPPGPNGEPG 110 GP G+ G G G GPPG G PG Sbjct: 729 ---GPKGASGPAGPPGAQGPPGLQGMPG 753 >gi|111118974 collagen, type II, alpha 1 isoform 2 precursor [Homo sapiens] Length = 1418 Score = 85.5 bits (210), Expect = 4e-17 Identities = 44/94 (46%), Positives = 52/94 (55%), Gaps = 9/94 (9%) Query: 21 PSGHPQPAGDDACSVQILVPGLKGDAGEKGDKGAPGRPGRVGPTGEKGDMGDKGQKGSVG 80 P G P PAG G G AGE+G +GA G PG VGP G G+ G G +G G Sbjct: 400 PKGEPGPAGPQ---------GAPGPAGEEGKRGARGEPGGVGPIGPPGERGAPGNRGFPG 450 Query: 81 RHGKIGPIGSKGEKGDSGDIGPPGPNGEPGLPCE 114 + G GP G+ GE+G SG GP G NG+PG P E Sbjct: 451 QDGLAGPKGAPGERGPSGLAGPKGANGDPGRPGE 484 Score = 79.0 bits (193), Expect = 4e-15 Identities = 41/92 (44%), Positives = 47/92 (51%), Gaps = 6/92 (6%) Query: 21 PSGHPQPAGDDACSVQILVPGLKGDAGEKGDKGAPGRPGRVGPTGEKGDMGDKGQKGSVG 80 P+G P G D PG KG+ GE G KG G PG GP+G G G G G G Sbjct: 763 PAGFAGPPGADG------QPGAKGEQGEAGQKGDAGAPGPQGPSGAPGPQGPTGVTGPKG 816 Query: 81 RHGKIGPIGSKGEKGDSGDIGPPGPNGEPGLP 112 G GP G+ G G +G +GPPG NG PG P Sbjct: 817 ARGAQGPPGATGFPGAAGRVGPPGSNGNPGPP 848 Score = 74.3 bits (181), Expect = 1e-13 Identities = 42/93 (45%), Positives = 51/93 (54%), Gaps = 3/93 (3%) Query: 22 SGHPQPAGDDACSVQILVPGLKGDAGEKGDKGAPGRPGRVGPTGEKGDMGDKGQKGSVGR 81 SG P AG+ PG KG+ G+ G GA G PG G G++G +G GQ+G G Sbjct: 866 SGPPGRAGEPGLQGPAGPPGEKGEPGDDGPSGAEGPPGPQGLAGQRGIVGLPGQRGERGF 925 Query: 82 HGKIGPIGSKGEK---GDSGDIGPPGPNGEPGL 111 G GP G G++ G SGD GPPGP G PGL Sbjct: 926 PGLPGPSGEPGKQGAPGASGDRGPPGPVGPPGL 958 Score = 73.9 bits (180), Expect = 1e-13 Identities = 45/108 (41%), Positives = 54/108 (50%), Gaps = 9/108 (8%) Query: 8 VGVLISLAFLSLLPSGHPQPAGDDACSVQILVPGLKGDAGEKGD----KGAPGRPGRVGP 63 +G +L L+LL + + G D + PG KG GE GD G G PG GP Sbjct: 4 LGAPQTLVLLTLLVAAVLRCQGQD-----VRQPGPKGQKGEPGDIKDIVGPKGPPGPQGP 58 Query: 64 TGEKGDMGDKGQKGSVGRHGKIGPIGSKGEKGDSGDIGPPGPNGEPGL 111 GE+G GD+G KG G G G G G G+ G GPPGP G PGL Sbjct: 59 AGEQGPRGDRGDKGEKGAPGPRGRDGEPGTPGNPGPPGPPGPPGPPGL 106 Score = 73.9 bits (180), Expect = 1e-13 Identities = 41/88 (46%), Positives = 46/88 (52%), Gaps = 3/88 (3%) Query: 23 GHPQPAGDDACSVQILVPGLKGDAGEKGDKGAPGRPGRVGPTGEKGDMGDKGQKGSVGRH 82 G P PAG +PG KG AG G GAPG PG GP G +G G G KG Sbjct: 330 GSPGPAGASGNPGTDGIPGAKGSAGAPGIAGAPGFPGPRGPPGPQGATGPLGPKGQT--- 386 Query: 83 GKIGPIGSKGEKGDSGDIGPPGPNGEPG 110 G+ G G KGE+G G+ GP GP G PG Sbjct: 387 GEPGIAGFKGEQGPKGEPGPAGPQGAPG 414 Score = 73.6 bits (179), Expect = 2e-13 Identities = 36/75 (48%), Positives = 44/75 (58%), Gaps = 3/75 (4%) Query: 41 GLKGDAGEKGDKGAPGRP---GRVGPTGEKGDMGDKGQKGSVGRHGKIGPIGSKGEKGDS 97 G +GD GEKG +GAPG+ G GP G G G G+KG VG G G G++G G+ Sbjct: 696 GDRGDVGEKGPEGAPGKDGGRGLTGPIGPPGPAGANGEKGEVGPPGPAGSAGARGAPGER 755 Query: 98 GDIGPPGPNGEPGLP 112 G+ GPPGP G G P Sbjct: 756 GETGPPGPAGFAGPP 770 Score = 73.2 bits (178), Expect = 2e-13 Identities = 40/96 (41%), Positives = 51/96 (53%), Gaps = 12/96 (12%) Query: 21 PSGHPQPAGDDACSVQILVPGLKGDAGEKGDKGAPGRPGRVGPTGEKGDMGDKGQKGS-- 78 P G P P+G D G +GD+G G G PG G GP GEKG+ GD G G+ Sbjct: 847 PPGPPGPSGKDGPK------GARGDSGPPGRAGEPGLQGPAGPPGEKGEPGDDGPSGAEG 900 Query: 79 ----VGRHGKIGPIGSKGEKGDSGDIGPPGPNGEPG 110 G G+ G +G G++G+ G G PGP+GEPG Sbjct: 901 PPGPQGLAGQRGIVGLPGQRGERGFPGLPGPSGEPG 936 Score = 72.4 bits (176), Expect = 4e-13 Identities = 39/90 (43%), Positives = 45/90 (50%), Gaps = 3/90 (3%) Query: 21 PSGHPQPAGDDACSVQILVPGLKGDAGEKGDKGAPGRPGRVGPTGEKGDMGDKGQKGSVG 80 P G PAG PGL+G GE+G G G G G GEKG G G+ G G Sbjct: 661 PKGASGPAGPPGAQGP---PGLQGMPGERGAAGIAGPKGDRGDVGEKGPEGAPGKDGGRG 717 Query: 81 RHGKIGPIGSKGEKGDSGDIGPPGPNGEPG 110 G IGP G G G+ G++GPPGP G G Sbjct: 718 LTGPIGPPGPAGANGEKGEVGPPGPAGSAG 747 Score = 72.4 bits (176), Expect = 4e-13 Identities = 38/91 (41%), Positives = 45/91 (49%) Query: 21 PSGHPQPAGDDACSVQILVPGLKGDAGEKGDKGAPGRPGRVGPTGEKGDMGDKGQKGSVG 80 PSG P G + Q + GL G GE+G G PG G G G G GD+G G VG Sbjct: 895 PSGAEGPPGPQGLAGQRGIVGLPGQRGERGFPGLPGPSGEPGKQGAPGASGDRGPPGPVG 954 Query: 81 RHGKIGPIGSKGEKGDSGDIGPPGPNGEPGL 111 G GP G G +G G GPPG +G G+ Sbjct: 955 PPGLTGPAGEPGREGSPGADGPPGRDGAAGV 985 Score = 72.0 bits (175), Expect = 5e-13 Identities = 39/92 (42%), Positives = 45/92 (48%), Gaps = 6/92 (6%) Query: 23 GHPQPAGDDACSVQILVPGLKGDAGEKGDKGAPGRPGRVGPTGEKGDMGDKGQKGSVGRH 82 G P G D + G+KGD GE G GAPG PG G G G G +G +G G Sbjct: 972 GADGPPGRDGAA------GVKGDRGETGAVGAPGAPGPPGSPGPAGPTGKQGDRGEAGAQ 1025 Query: 83 GKIGPIGSKGEKGDSGDIGPPGPNGEPGLPCE 114 G +GP G G +G G GP G GE G P E Sbjct: 1026 GPMGPSGPAGARGIQGPQGPRGDKGEAGEPGE 1057 Score = 71.2 bits (173), Expect = 9e-13 Identities = 36/74 (48%), Positives = 39/74 (52%), Gaps = 3/74 (4%) Query: 40 PGLKGDAGEKGDKGAPGRPGRVGPTGE---KGDMGDKGQKGSVGRHGKIGPIGSKGEKGD 96 PG G G G G PG PG GP+G+ KG GD G G G G GP G GEKG+ Sbjct: 830 PGAAGRVGPPGSNGNPGPPGPPGPSGKDGPKGARGDSGPPGRAGEPGLQGPAGPPGEKGE 889 Query: 97 SGDIGPPGPNGEPG 110 GD GP G G PG Sbjct: 890 PGDDGPSGAEGPPG 903 Score = 70.9 bits (172), Expect = 1e-12 Identities = 40/97 (41%), Positives = 52/97 (53%), Gaps = 9/97 (9%) Query: 23 GHPQPAGDDACSVQILVPGLKGDAGEKGDKGAPGR---PGRVGPTGEKGDMGDKGQKGS- 78 G P +GD + PGL G AGE G +G+PG PGR G G KGD G+ G G+ Sbjct: 939 GAPGASGDRGPPGPVGPPGLTGPAGEPGREGSPGADGPPGRDGAAGVKGDRGETGAVGAP 998 Query: 79 -----VGRHGKIGPIGSKGEKGDSGDIGPPGPNGEPG 110 G G GP G +G++G++G GP GP+G G Sbjct: 999 GAPGPPGSPGPAGPTGKQGDRGEAGAQGPMGPSGPAG 1035 Score = 70.9 bits (172), Expect = 1e-12 Identities = 34/72 (47%), Positives = 41/72 (56%) Query: 41 GLKGDAGEKGDKGAPGRPGRVGPTGEKGDMGDKGQKGSVGRHGKIGPIGSKGEKGDSGDI 100 GL G G GD+GA G G GP G G +G G+ G+ G G IGP G +G G++G Sbjct: 1071 GLPGPPGPSGDQGASGPAGPSGPRGPPGPVGPSGKDGANGIPGPIGPPGPRGRSGETGPA 1130 Query: 101 GPPGPNGEPGLP 112 GPPG G PG P Sbjct: 1131 GPPGNPGPPGPP 1142 Score = 70.5 bits (171), Expect = 1e-12 Identities = 42/111 (37%), Positives = 52/111 (46%), Gaps = 21/111 (18%) Query: 23 GHPQPAGDDACSVQILVPGLKGDAGEKGD---------KGAPGRPGRVGPTGEKGDMGDK 73 GH G D + PG+KG++G G+ +G PG GR GP G G G+ Sbjct: 219 GHRGYPGLDGAKGEAGAPGVKGESGSPGENGSPGPMGPRGLPGERGRTGPAGAAGARGND 278 Query: 74 GQKGSVGRHGKIGPI---------GSKGEKGDSGDIGP---PGPNGEPGLP 112 GQ G G G +GP G+KGE G +G GP GP GEPG P Sbjct: 279 GQPGPAGPPGPVGPAGGPGFPGAPGAKGEAGPTGARGPEGAQGPRGEPGTP 329 Score = 70.5 bits (171), Expect = 1e-12 Identities = 37/78 (47%), Positives = 45/78 (57%), Gaps = 6/78 (7%) Query: 40 PGLKGDAGEKGDKGAPGR---PGRVGPTGEKGDMGDKGQKGSVGRHGK---IGPIGSKGE 93 PG G+ G+ GD+G PG PG VGP GE+G G++G G+ G G G G+ G Sbjct: 602 PGPPGEGGKPGDQGVPGEAGAPGLVGPRGERGFPGERGSPGAQGLQGPRGLPGTPGTDGP 661 Query: 94 KGDSGDIGPPGPNGEPGL 111 KG SG GPPG G PGL Sbjct: 662 KGASGPAGPPGAQGPPGL 679 Score = 70.5 bits (171), Expect = 1e-12 Identities = 41/104 (39%), Positives = 51/104 (49%), Gaps = 12/104 (11%) Query: 21 PSGHPQPAGDDACSVQILVPGLKGDAG------EKGDKGAPGRPGRVGPTGE------KG 68 P G P PAG + ++ PG G AG E+G+ G PG G GP G KG Sbjct: 721 PIGPPGPAGANGEKGEVGPPGPAGSAGARGAPGERGETGPPGPAGFAGPPGADGQPGAKG 780 Query: 69 DMGDKGQKGSVGRHGKIGPIGSKGEKGDSGDIGPPGPNGEPGLP 112 + G+ GQKG G G GP G+ G +G +G GP G G G P Sbjct: 781 EQGEAGQKGDAGAPGPQGPSGAPGPQGPTGVTGPKGARGAQGPP 824 Score = 70.5 bits (171), Expect = 1e-12 Identities = 37/82 (45%), Positives = 48/82 (58%), Gaps = 9/82 (10%) Query: 40 PGLKGDAGEKGDKGAPGR------PGRVGPTGEKGDMGDKGQKGSVGRHG---KIGPIGS 90 PGL G +GE G +GAPG PG VGP G G G+ G++GS G G + G G Sbjct: 926 PGLPGPSGEPGKQGAPGASGDRGPPGPVGPPGLTGPAGEPGREGSPGADGPPGRDGAAGV 985 Query: 91 KGEKGDSGDIGPPGPNGEPGLP 112 KG++G++G +G PG G PG P Sbjct: 986 KGDRGETGAVGAPGAPGPPGSP 1007 Score = 70.1 bits (170), Expect = 2e-12 Identities = 36/83 (43%), Positives = 44/83 (53%) Query: 29 GDDACSVQILVPGLKGDAGEKGDKGAPGRPGRVGPTGEKGDMGDKGQKGSVGRHGKIGPI 88 G D + PG +G +G G KGA G PGR G G G G G+ G G GK+GP Sbjct: 450 GQDGLAGPKGAPGERGPSGLAGPKGANGDPGRPGEPGLPGARGLTGRPGDAGPQGKVGPS 509 Query: 89 GSKGEKGDSGDIGPPGPNGEPGL 111 G+ GE G G GP G G+PG+ Sbjct: 510 GAPGEDGRPGPPGPQGARGQPGV 532 Score = 70.1 bits (170), Expect = 2e-12 Identities = 39/96 (40%), Positives = 46/96 (47%), Gaps = 6/96 (6%) Query: 21 PSGHPQPAGDDACSVQILVPGLKGDAGEKGDKGAPGRPGRVGPTGEKGDMGD------KG 74 P G P PAG G +G G G GA G G GP G+KG+ G+ KG Sbjct: 1003 PPGSPGPAGPTGKQGDRGEAGAQGPMGPSGPAGARGIQGPQGPRGDKGEAGEPGERGLKG 1062 Query: 75 QKGSVGRHGKIGPIGSKGEKGDSGDIGPPGPNGEPG 110 +G G G GP G G++G SG GP GP G PG Sbjct: 1063 HRGFTGLQGLPGPPGPSGDQGASGPAGPSGPRGPPG 1098 Score = 69.7 bits (169), Expect = 3e-12 Identities = 38/82 (46%), Positives = 45/82 (54%), Gaps = 9/82 (10%) Query: 40 PGLKGDAGEKGDKGAPGR------PGRVGPTGEKGDMGDKGQKGSVGRHGKIGPIGSK-- 91 PG G AGE+G++GAPG PG GP GE G GD+G G G G +GP G + Sbjct: 575 PGPAGPAGERGEQGAPGPSGFQGLPGPPGPPGEGGKPGDQGVPGEAGAPGLVGPRGERGF 634 Query: 92 -GEKGDSGDIGPPGPNGEPGLP 112 GE+G G G GP G PG P Sbjct: 635 PGERGSPGAQGLQGPRGLPGTP 656 Score = 69.7 bits (169), Expect = 3e-12 Identities = 40/91 (43%), Positives = 43/91 (47%), Gaps = 12/91 (13%) Query: 21 PSGHPQPAGDDACSVQILVPGLKGDAGEKGDKGAPGRPGRVGPTGEKGDMGDKGQKGSVG 80 PSG P P G G G KG +GA G PG G G G +G G G+ G Sbjct: 799 PSGAPGPQGPT------------GVTGPKGARGAQGPPGATGFPGAAGRVGPPGSNGNPG 846 Query: 81 RHGKIGPIGSKGEKGDSGDIGPPGPNGEPGL 111 G GP G G KG GD GPPG GEPGL Sbjct: 847 PPGPPGPSGKDGPKGARGDSGPPGRAGEPGL 877 Score = 69.3 bits (168), Expect = 3e-12 Identities = 41/99 (41%), Positives = 50/99 (50%), Gaps = 9/99 (9%) Query: 22 SGHPQPAGDDACSVQILVPGLKGDAGEKGDKGAPGRPGRVGPTGEKGDMGDKGQKGSVGR 81 +G P AG+ PGL+G G+ G+ GA G PG GP GE+G+ G G G G Sbjct: 542 NGEPGKAGEKGLPG---APGLRGLPGKDGETGAAGPPGPAGPAGERGEQGAPGPSGFQGL 598 Query: 82 HGKIGPIGSKGEKGDS---GDIGPP---GPNGEPGLPCE 114 G GP G G+ GD G+ G P GP GE G P E Sbjct: 599 PGPPGPPGEGGKPGDQGVPGEAGAPGLVGPRGERGFPGE 637 Score = 68.2 bits (165), Expect = 7e-12 Identities = 39/99 (39%), Positives = 46/99 (46%), Gaps = 9/99 (9%) Query: 21 PSGHPQPAGDDACSVQILVPGLKGDAGEKGDKGAPGR---------PGRVGPTGEKGDMG 71 P G PAG G KG+AGE G++G G PG GP+G++G G Sbjct: 1027 PMGPSGPAGARGIQGPQGPRGDKGEAGEPGERGLKGHRGFTGLQGLPGPPGPSGDQGASG 1086 Query: 72 DKGQKGSVGRHGKIGPIGSKGEKGDSGDIGPPGPNGEPG 110 G G G G +GP G G G G IGPPGP G G Sbjct: 1087 PAGPSGPRGPPGPVGPSGKDGANGIPGPIGPPGPRGRSG 1125 Score = 67.8 bits (164), Expect = 1e-11 Identities = 40/99 (40%), Positives = 48/99 (48%), Gaps = 9/99 (9%) Query: 23 GHPQPAGDDACSVQILVPGLKGDAGEKGDKGAPGRPGR---------VGPTGEKGDMGDK 73 G P GD + + GLKG G G +G PG PG GP+G +G G Sbjct: 1041 GPQGPRGDKGEAGEPGERGLKGHRGFTGLQGLPGPPGPSGDQGASGPAGPSGPRGPPGPV 1100 Query: 74 GQKGSVGRHGKIGPIGSKGEKGDSGDIGPPGPNGEPGLP 112 G G G +G GPIG G +G SG+ GP GP G PG P Sbjct: 1101 GPSGKDGANGIPGPIGPPGPRGRSGETGPAGPPGNPGPP 1139 Score = 67.4 bits (163), Expect = 1e-11 Identities = 40/99 (40%), Positives = 47/99 (47%), Gaps = 9/99 (9%) Query: 21 PSGHPQPAGDDACSVQILVPGLKGDAGEKGDKGAP---------GRPGRVGPTGEKGDMG 71 P G P G + I PG G GEKG+ G P G PG G TG G G Sbjct: 706 PEGAPGKDGGRGLTGPIGPPGPAGANGEKGEVGPPGPAGSAGARGAPGERGETGPPGPAG 765 Query: 72 DKGQKGSVGRHGKIGPIGSKGEKGDSGDIGPPGPNGEPG 110 G G+ G+ G G G G+KGD+G GP GP+G PG Sbjct: 766 FAGPPGADGQPGAKGEQGEAGQKGDAGAPGPQGPSGAPG 804 Score = 67.4 bits (163), Expect = 1e-11 Identities = 39/96 (40%), Positives = 47/96 (48%), Gaps = 6/96 (6%) Query: 21 PSGHPQPAGDDACSVQILVPGLKGDAGEKGDKGAPGR------PGRVGPTGEKGDMGDKG 74 P G GDD S PG +G AG++G G PG+ PG GP+GE G G G Sbjct: 883 PPGEKGEPGDDGPSGAEGPPGPQGLAGQRGIVGLPGQRGERGFPGLPGPSGEPGKQGAPG 942 Query: 75 QKGSVGRHGKIGPIGSKGEKGDSGDIGPPGPNGEPG 110 G G G +GP G G G+ G G PG +G PG Sbjct: 943 ASGDRGPPGPVGPPGLTGPAGEPGREGSPGADGPPG 978 Score = 67.0 bits (162), Expect = 2e-11 Identities = 37/94 (39%), Positives = 45/94 (47%), Gaps = 6/94 (6%) Query: 23 GHPQPAGDDACSVQILVPGLKGDAG------EKGDKGAPGRPGRVGPTGEKGDMGDKGQK 76 G P P G +PG+KG G KG+ GAPG G G GE G G G + Sbjct: 198 GPPGPQGARGFPGTPGLPGVKGHRGYPGLDGAKGEAGAPGVKGESGSPGENGSPGPMGPR 257 Query: 77 GSVGRHGKIGPIGSKGEKGDSGDIGPPGPNGEPG 110 G G G+ GP G+ G +G+ G GP GP G G Sbjct: 258 GLPGERGRTGPAGAAGARGNDGQPGPAGPPGPVG 291 Score = 67.0 bits (162), Expect = 2e-11 Identities = 37/89 (41%), Positives = 42/89 (47%), Gaps = 9/89 (10%) Query: 23 GHPQPAGDDACSVQILVPGLKGDAGEKGDKGAPGRPGRVGPTGEKGDMGDKGQKGSVGRH 82 G P PAG PG G AG G GAPG G GPTG +G G +G +G G Sbjct: 279 GQPGPAGP---------PGPVGPAGGPGFPGAPGAKGEAGPTGARGPEGAQGPRGEPGTP 329 Query: 83 GKIGPIGSKGEKGDSGDIGPPGPNGEPGL 111 G GP G+ G G G G G G PG+ Sbjct: 330 GSPGPAGASGNPGTDGIPGAKGSAGAPGI 358 Score = 65.5 bits (158), Expect = 5e-11 Identities = 35/79 (44%), Positives = 40/79 (50%), Gaps = 9/79 (11%) Query: 41 GLKGDAGEKGDKGAPGRPG---------RVGPTGEKGDMGDKGQKGSVGRHGKIGPIGSK 91 GL G G GD G PG PG R G G +G +G G G GR G GP G++ Sbjct: 468 GLAGPKGANGDPGRPGEPGLPGARGLTGRPGDAGPQGKVGPSGAPGEDGRPGPPGPQGAR 527 Query: 92 GEKGDSGDIGPPGPNGEPG 110 G+ G G GP G NGEPG Sbjct: 528 GQPGVMGFPGPKGANGEPG 546 Score = 65.1 bits (157), Expect = 6e-11 Identities = 36/90 (40%), Positives = 42/90 (46%) Query: 21 PSGHPQPAGDDACSVQILVPGLKGDAGEKGDKGAPGRPGRVGPTGEKGDMGDKGQKGSVG 80 P G P P G + PG G+ G G +GA G PG G G KG G G G+ G Sbjct: 172 PRGPPGPPGKPGDDGEAGKPGKAGERGPPGPQGARGFPGTPGLPGVKGHRGYPGLDGAKG 231 Query: 81 RHGKIGPIGSKGEKGDSGDIGPPGPNGEPG 110 G G G G G++G GP GP G PG Sbjct: 232 EAGAPGVKGESGSPGENGSPGPMGPRGLPG 261 Score = 65.1 bits (157), Expect = 6e-11 Identities = 38/94 (40%), Positives = 46/94 (48%), Gaps = 3/94 (3%) Query: 22 SGHPQPAGDDACSVQILVPGLKGDAGEKGDKGAPGR---PGRVGPTGEKGDMGDKGQKGS 78 +G P P G + G G AG +G+ G PG PG VGP G G G G KG Sbjct: 248 NGSPGPMGPRGLPGERGRTGPAGAAGARGNDGQPGPAGPPGPVGPAGGPGFPGAPGAKGE 307 Query: 79 VGRHGKIGPIGSKGEKGDSGDIGPPGPNGEPGLP 112 G G GP G++G +G+ G G PGP G G P Sbjct: 308 AGPTGARGPEGAQGPRGEPGTPGSPGPAGASGNP 341 Score = 65.1 bits (157), Expect = 6e-11 Identities = 40/109 (36%), Positives = 49/109 (44%), Gaps = 18/109 (16%) Query: 21 PSGHPQPAGDDACSVQILVPGLKGDA------------GEKGDKGAPGRPGRVGPTGEKG 68 P+G P P G PG KG+A G +G+ G PG PG G +G G Sbjct: 283 PAGPPGPVGPAGGPGFPGAPGAKGEAGPTGARGPEGAQGPRGEPGTPGSPGPAGASGNPG 342 Query: 69 DMGDKGQKGSVGRHGKI------GPIGSKGEKGDSGDIGPPGPNGEPGL 111 G G KGS G G GP G G +G +G +GP G GEPG+ Sbjct: 343 TDGIPGAKGSAGAPGIAGAPGFPGPRGPPGPQGATGPLGPKGQTGEPGI 391 Score = 65.1 bits (157), Expect = 6e-11 Identities = 38/96 (39%), Positives = 45/96 (46%), Gaps = 6/96 (6%) Query: 23 GHPQPAGDDACSVQILVPGL------KGDAGEKGDKGAPGRPGRVGPTGEKGDMGDKGQK 76 G P P G Q V G G+ G+ G+KG PG PG G G+ G+ G G Sbjct: 516 GRPGPPGPQGARGQPGVMGFPGPKGANGEPGKAGEKGLPGAPGLRGLPGKDGETGAAGPP 575 Query: 77 GSVGRHGKIGPIGSKGEKGDSGDIGPPGPNGEPGLP 112 G G G+ G G+ G G G GPPGP GE G P Sbjct: 576 GPAGPAGERGEQGAPGPSGFQGLPGPPGPPGEGGKP 611 Score = 65.1 bits (157), Expect = 6e-11 Identities = 44/140 (31%), Positives = 59/140 (42%), Gaps = 21/140 (15%) Query: 23 GHPQPAGDDACSVQILVPGLKGDAGEKGDKGAPGRPGRVGPTGEKGDMGDKGQKGSVGRH 82 G P P+GD G G AG G +G PG G G G G G G G GR Sbjct: 1074 GPPGPSGDQ---------GASGPAGPSGPRGPPGPVGPSGKDGANGIPGPIGPPGPRGRS 1124 Query: 83 GKIGPIGSKGEKGDSGDIGPPGP----NGEPGL--------PCECSQLRKAIGEMDNQVS 130 G+ GP G G G G GPPGP + GL P + + +A G + + Sbjct: 1125 GETGPAGPPGNPGPPGPPGPPGPGIDMSAFAGLGPREKGPDPLQYMRADQAAGGLRQHDA 1184 Query: 131 QLTSELKFIKNAVAGVRETE 150 ++ + LK + N + +R E Sbjct: 1185 EVDATLKSLNNQIESIRSPE 1204 Score = 64.7 bits (156), Expect = 8e-11 Identities = 37/90 (41%), Positives = 44/90 (48%) Query: 21 PSGHPQPAGDDACSVQILVPGLKGDAGEKGDKGAPGRPGRVGPTGEKGDMGDKGQKGSVG 80 P G P GDD + + G +G G +G +G PG PG G G +G G G KG G Sbjct: 175 PPGPPGKPGDDGEAGKPGKAGERGPPGPQGARGFPGTPGLPGVKGHRGYPGLDGAKGEAG 234 Query: 81 RHGKIGPIGSKGEKGDSGDIGPPGPNGEPG 110 G G GS GE G G +GP G GE G Sbjct: 235 APGVKGESGSPGENGSPGPMGPRGLPGERG 264 Score = 64.3 bits (155), Expect = 1e-10 Identities = 36/92 (39%), Positives = 44/92 (47%), Gaps = 6/92 (6%) Query: 21 PSGHPQPAGDDACSVQILVPGLKGDAGEKGDKGAPGRPGRVGPTGEKGDMGDKGQKGSVG 80 P G P PAG G +G+ GE G+ G G G GP G G GD G+ G G Sbjct: 139 PRGPPGPAGAPGPQ------GFQGNPGEPGEPGVSGPMGPRGPPGPPGKPGDDGEAGKPG 192 Query: 81 RHGKIGPIGSKGEKGDSGDIGPPGPNGEPGLP 112 + G+ GP G +G +G G G PG G G P Sbjct: 193 KAGERGPPGPQGARGFPGTPGLPGVKGHRGYP 224 Score = 64.3 bits (155), Expect = 1e-10 Identities = 39/108 (36%), Positives = 45/108 (41%), Gaps = 18/108 (16%) Query: 21 PSGHPQPAGDDACSVQILVPGLKGDAGEKG---------------DKGAPGRPGRVGPTG 65 P G GD + PGL G GE+G +G PG PG GP G Sbjct: 604 PPGEGGKPGDQGVPGEAGAPGLVGPRGERGFPGERGSPGAQGLQGPRGLPGTPGTDGPKG 663 Query: 66 EKGDMGDKGQKGSVGRHG---KIGPIGSKGEKGDSGDIGPPGPNGEPG 110 G G G +G G G + G G G KGD GD+G GP G PG Sbjct: 664 ASGPAGPPGAQGPPGLQGMPGERGAAGIAGPKGDRGDVGEKGPEGAPG 711 Score = 63.2 bits (152), Expect = 2e-10 Identities = 35/97 (36%), Positives = 47/97 (48%), Gaps = 6/97 (6%) Query: 16 FLSLLPSGHPQPAGDDACSVQILVPGLKGDAGEKGDKGAPGRPGRVGPTGEKGDMGDKGQ 75 F + + G + AG V ++G G G +G PG G GP G +G+ G+ G+ Sbjct: 110 FAAQMAGGFDEKAGGAQLGV------MQGPMGPMGPRGPPGPAGAPGPQGFQGNPGEPGE 163 Query: 76 KGSVGRHGKIGPIGSKGEKGDSGDIGPPGPNGEPGLP 112 G G G GP G G+ GD G+ G PG GE G P Sbjct: 164 PGVSGPMGPRGPPGPPGKPGDDGEAGKPGKAGERGPP 200 Score = 62.4 bits (150), Expect = 4e-10 Identities = 36/92 (39%), Positives = 45/92 (48%) Query: 21 PSGHPQPAGDDACSVQILVPGLKGDAGEKGDKGAPGRPGRVGPTGEKGDMGDKGQKGSVG 80 PSG P G + + PGL G G G G G G+VGP+G G+ G G G G Sbjct: 466 PSGLAGPKGANGDPGRPGEPGLPGARGLTGRPGDAGPQGKVGPSGAPGEDGRPGPPGPQG 525 Query: 81 RHGKIGPIGSKGEKGDSGDIGPPGPNGEPGLP 112 G+ G +G G KG +G+ G G G PG P Sbjct: 526 ARGQPGVMGFPGPKGANGEPGKAGEKGLPGAP 557 Score = 62.0 bits (149), Expect = 5e-10 Identities = 35/89 (39%), Positives = 44/89 (49%) Query: 22 SGHPQPAGDDACSVQILVPGLKGDAGEKGDKGAPGRPGRVGPTGEKGDMGDKGQKGSVGR 81 +G P AG PG G G G +GA G+PG +G G KG G+ G+ G G Sbjct: 494 TGRPGDAGPQGKVGPSGAPGEDGRPGPPGPQGARGQPGVMGFPGPKGANGEPGKAGEKGL 553 Query: 82 HGKIGPIGSKGEKGDSGDIGPPGPNGEPG 110 G G G G+ G++G GPPGP G G Sbjct: 554 PGAPGLRGLPGKDGETGAAGPPGPAGPAG 582 Score = 60.8 bits (146), Expect = 1e-09 Identities = 37/107 (34%), Positives = 47/107 (43%), Gaps = 15/107 (14%) Query: 23 GHPQPAGDDACSVQILVPGLKGDAGEKGDKGAPGRPGRVGPTGEKGDMGDKGQKGSV--- 79 G+P G+ S + G G G+ GD G G+PG+ G G G G +G G+ Sbjct: 156 GNPGEPGEPGVSGPMGPRGPPGPPGKPGDDGEAGKPGKAGERGPPGPQGARGFPGTPGLP 215 Query: 80 ------------GRHGKIGPIGSKGEKGDSGDIGPPGPNGEPGLPCE 114 G G+ G G KGE G G+ G PGP G GLP E Sbjct: 216 GVKGHRGYPGLDGAKGEAGAPGVKGESGSPGENGSPGPMGPRGLPGE 262 Score = 60.8 bits (146), Expect = 1e-09 Identities = 32/72 (44%), Positives = 35/72 (48%) Query: 41 GLKGDAGEKGDKGAPGRPGRVGPTGEKGDMGDKGQKGSVGRHGKIGPIGSKGEKGDSGDI 100 G G G G KGAPG G G G KG GD G+ G G G G G G+ G G + Sbjct: 447 GFPGQDGLAGPKGAPGERGPSGLAGPKGANGDPGRPGEPGLPGARGLTGRPGDAGPQGKV 506 Query: 101 GPPGPNGEPGLP 112 GP G GE G P Sbjct: 507 GPSGAPGEDGRP 518 Score = 60.1 bits (144), Expect = 2e-09 Identities = 42/122 (34%), Positives = 48/122 (39%), Gaps = 30/122 (24%) Query: 21 PSGHPQPAGDDACSVQILVPGLKGDAGEKGDKGAPGRPGRVGPTG--------------- 65 P+G P GD + PG +G GE G G PG PG GP G Sbjct: 58 PAGEQGPRGDRGDKGEKGAPGPRGRDGEPGTPGNPGPPGPPGPPGPPGLGGNFAAQMAGG 117 Query: 66 --EK-------------GDMGDKGQKGSVGRHGKIGPIGSKGEKGDSGDIGPPGPNGEPG 110 EK G MG +G G G G G G+ GE G+ G GP GP G PG Sbjct: 118 FDEKAGGAQLGVMQGPMGPMGPRGPPGPAGAPGPQGFQGNPGEPGEPGVSGPMGPRGPPG 177 Query: 111 LP 112 P Sbjct: 178 PP 179 Score = 59.3 bits (142), Expect = 3e-09 Identities = 35/93 (37%), Positives = 48/93 (51%), Gaps = 6/93 (6%) Query: 21 PSGHPQPAGDDACSVQILVPGLKGDAGEKGDKGAPGRPGRVGPTGEK---GDMGDKGQKG 77 P G P P G + + G G+ G G KG G G GP G + G G++G++G Sbjct: 367 PRGPPGPQG---ATGPLGPKGQTGEPGIAGFKGEQGPKGEPGPAGPQGAPGPAGEEGKRG 423 Query: 78 SVGRHGKIGPIGSKGEKGDSGDIGPPGPNGEPG 110 + G G +GPIG GE+G G+ G PG +G G Sbjct: 424 ARGEPGGVGPIGPPGERGAPGNRGFPGQDGLAG 456 Score = 57.8 bits (138), Expect = 1e-08 Identities = 35/91 (38%), Positives = 44/91 (48%), Gaps = 3/91 (3%) Query: 22 SGHPQPAGDDACSVQILVPGLKGDAGEKGDKGAPGRPGRVGPTGEKGDMGDKGQKGSVGR 81 +G P G+ + G GDAG +G G G PG G G G G +GQ G +G Sbjct: 476 NGDPGRPGEPGLPGARGLTGRPGDAGPQGKVGPSGAPGEDGRPGPPGPQGARGQPGVMGF 535 Query: 82 HGKIGPIGSKGEKGDSGDIGPPGPNGEPGLP 112 GP G+ GE G +G+ G PG G GLP Sbjct: 536 P---GPKGANGEPGKAGEKGLPGAPGLRGLP 563 Score = 55.1 bits (131), Expect = 6e-08 Identities = 34/88 (38%), Positives = 40/88 (45%), Gaps = 3/88 (3%) Query: 23 GHPQPAGDDACSVQILVPGLKGDAGEKGDKGAPGRPGRVGPTGEKGDMGDKGQKGSVGRH 82 G P P G+ VPG G G G +G G PG G G +G G +G G+ G Sbjct: 600 GPPGPPGEGGKPGDQGVPGEAGAPGLVGPRGERGFPGERGSPGAQGLQGPRGLPGTPGTD 659 Query: 83 GKIGPIGSKGEKGDSGDIGPPGPNGEPG 110 GP G+ G G G GPPG G PG Sbjct: 660 ---GPKGASGPAGPPGAQGPPGLQGMPG 684 Score = 53.5 bits (127), Expect = 2e-07 Identities = 31/73 (42%), Positives = 37/73 (50%), Gaps = 21/73 (28%) Query: 40 PGLKGDAGEKGDKGAPGRPGRVGPTGEKGDMGDKGQKGSVGRHGKIGPIGSKGEKGDSGD 99 PG +G AGE+ G +GD GDKG+KG+ GP G GE G G+ Sbjct: 53 PGPQGPAGEQ---------------GPRGDRGDKGEKGAP------GPRGRDGEPGTPGN 91 Query: 100 IGPPGPNGEPGLP 112 GPPGP G PG P Sbjct: 92 PGPPGPPGPPGPP 104 >gi|111118972 collagen, type XI, alpha 2 isoform 2 preproprotein [Homo sapiens] Length = 1650 Score = 83.6 bits (205), Expect = 2e-16 Identities = 45/111 (40%), Positives = 59/111 (53%), Gaps = 21/111 (18%) Query: 21 PSGHPQPAGDDACSVQILVPGLKGDAGEKGDKGAPGRPGRVGPTGE-------------- 66 P+G P AG+D ++ PG KG G KG+ G PG PG +GP G+ Sbjct: 987 PAGPPGVAGEDGDKGEVGDPGQKGTKGNKGEHGPPGPPGPIGPVGQPGAAGADGEPGARG 1046 Query: 67 -KGDMGDKGQKGSVGRHGKIGPI------GSKGEKGDSGDIGPPGPNGEPG 110 +G G KG +G+ G +G GPI G GEKG++GD+GP GP G PG Sbjct: 1047 PQGHFGAKGDEGTRGFNGPPGPIGLQGLPGPSGEKGETGDVGPMGPPGPPG 1097 Score = 80.5 bits (197), Expect = 1e-15 Identities = 43/91 (47%), Positives = 52/91 (57%), Gaps = 12/91 (13%) Query: 22 SGHPQPAGDDACSVQILVPGLKGDAGEKGDKGAPGRPGRVGPTGEKGDMGDKGQKGSVGR 81 +G P P G +PGL+GDAG KG+KG PG G +GP GE+G+ GD+G G G Sbjct: 1300 AGPPGPVGPPG------LPGLRGDAGAKGEKGHPGLIGLIGPPGEQGEKGDRGLPGPQGS 1353 Query: 82 HGKIGPIGSKGEKGDSGDIGPPGPNGEPGLP 112 G+ KGE G G GP GP G PGLP Sbjct: 1354 PGQ------KGEMGIPGASGPIGPGGPPGLP 1378 Score = 78.6 bits (192), Expect = 5e-15 Identities = 39/90 (43%), Positives = 47/90 (52%) Query: 21 PSGHPQPAGDDACSVQILVPGLKGDAGEKGDKGAPGRPGRVGPTGEKGDMGDKGQKGSVG 80 P+G P G + PG KG+ GE G G G PG GP GE+G+ G+ GQ G G Sbjct: 1104 PNGADGPQGPPGGVGNLGPPGEKGEPGESGSPGIQGEPGVKGPRGERGEKGESGQPGEPG 1163 Query: 81 RHGKIGPIGSKGEKGDSGDIGPPGPNGEPG 110 G GP G G KG+ G +G PG G PG Sbjct: 1164 PPGPKGPTGDDGPKGNPGPVGFPGDPGPPG 1193 Score = 78.2 bits (191), Expect = 7e-15 Identities = 40/90 (44%), Positives = 47/90 (52%) Query: 23 GHPQPAGDDACSVQILVPGLKGDAGEKGDKGAPGRPGRVGPTGEKGDMGDKGQKGSVGRH 82 G P +G + V G +G+ GEKG+ G PG PG GP G GD G KG G VG Sbjct: 1127 GEPGESGSPGIQGEPGVKGPRGERGEKGESGQPGEPGPPGPKGPTGDDGPKGNPGPVGFP 1186 Query: 83 GKIGPIGSKGEKGDSGDIGPPGPNGEPGLP 112 G GP G G +G G G G +GEPG P Sbjct: 1187 GDPGPPGEGGPRGQDGAKGDRGEDGEPGQP 1216 Score = 76.3 bits (186), Expect = 3e-14 Identities = 42/90 (46%), Positives = 46/90 (51%), Gaps = 6/90 (6%) Query: 21 PSGHPQPAGDDACSVQILVPGLKGDAGEKGDKGAPGRPGRVGPTGEKGDMGDKGQKGSVG 80 P+G P P G +PG G G G G G PG VGP G G GD G KG G Sbjct: 1272 PAGKPGPDGLRG------LPGSVGQQGRPGATGQAGPPGPVGPPGLPGLRGDAGAKGEKG 1325 Query: 81 RHGKIGPIGSKGEKGDSGDIGPPGPNGEPG 110 G IG IG GE+G+ GD G PGP G PG Sbjct: 1326 HPGLIGLIGPPGEQGEKGDRGLPGPQGSPG 1355 Score = 75.9 bits (185), Expect = 4e-14 Identities = 42/97 (43%), Positives = 51/97 (52%), Gaps = 12/97 (12%) Query: 23 GHPQPAGDDACSVQILVPGLKGDAGEKGDKGAPGRPGRVGPTGEKGDMGDKGQ------- 75 GHP P G + +PG G G KGD G PG PG+ GP G +G G++G Sbjct: 857 GHPGPPGPPG---EQGLPGTAGKEGTKGDPGPPGAPGKDGPAGLRGFPGERGLPGTAGGP 913 Query: 76 --KGSVGRHGKIGPIGSKGEKGDSGDIGPPGPNGEPG 110 KG+ G G GP GS GE+G +G GP GP G PG Sbjct: 914 GLKGNEGPSGPPGPAGSPGERGAAGSGGPIGPPGRPG 950 Score = 75.1 bits (183), Expect = 6e-14 Identities = 40/90 (44%), Positives = 46/90 (51%) Query: 21 PSGHPQPAGDDACSVQILVPGLKGDAGEKGDKGAPGRPGRVGPTGEKGDMGDKGQKGSVG 80 P G P P G + + VPG KG G G G G G GP G G G+ G KG VG Sbjct: 945 PPGRPGPQGPPGAAGEKGVPGEKGPIGPTGRDGVQGPVGLPGPAGPPGVAGEDGDKGEVG 1004 Query: 81 RHGKIGPIGSKGEKGDSGDIGPPGPNGEPG 110 G+ G G+KGE G G GP GP G+PG Sbjct: 1005 DPGQKGTKGNKGEHGPPGPPGPIGPVGQPG 1034 Score = 75.1 bits (183), Expect = 6e-14 Identities = 42/95 (44%), Positives = 50/95 (52%), Gaps = 3/95 (3%) Query: 21 PSGHPQPAGDDACSVQILVPGLKGDAGEKGDKGAPGR---PGRVGPTGEKGDMGDKGQKG 77 P G PAG + PG G+ G G+KG PG PG G G KG G++G+KG Sbjct: 1095 PPGPRGPAGPNGADGPQGPPGGVGNLGPPGEKGEPGESGSPGIQGEPGVKGPRGERGEKG 1154 Query: 78 SVGRHGKIGPIGSKGEKGDSGDIGPPGPNGEPGLP 112 G+ G+ GP G KG GD G G PGP G PG P Sbjct: 1155 ESGQPGEPGPPGPKGPTGDDGPKGNPGPVGFPGDP 1189 Score = 74.7 bits (182), Expect = 8e-14 Identities = 44/101 (43%), Positives = 51/101 (50%), Gaps = 9/101 (8%) Query: 21 PSGHPQPAGDDACSVQILVPGLKGDAGEKGDKGAPGRPGRVGPTGEKGDMGDKGQKGSVG 80 P+G P P G ++ VPGL G G +G KG+ G PG G +GEKG G G+ G G Sbjct: 693 PTGDPGPPGLMGEKGKLGVPGLPGYPGRQGPKGSLGFPGFPGASGEKGARGLSGKSGPRG 752 Query: 81 RHGKIGP---------IGSKGEKGDSGDIGPPGPNGEPGLP 112 G GP G G KG SG GP GP GE GLP Sbjct: 753 ERGPTGPRGQRGPRGATGKSGAKGTSGGDGPHGPPGERGLP 793 Score = 74.3 bits (181), Expect = 1e-13 Identities = 45/102 (44%), Positives = 50/102 (49%), Gaps = 21/102 (20%) Query: 21 PSGHPQPAGDDACSVQILVPGLKGDAGEKGDKGAPGRPGRVGP---TGEKGDMGDKGQKG 77 PSG P PAG PG +G AG G G PGRPG GP GEKG G+KG G Sbjct: 921 PSGPPGPAGS---------PGERGAAGSGGPIGPPGRPGPQGPPGAAGEKGVPGEKGPIG 971 Query: 78 SVGRHGKIGPI---------GSKGEKGDSGDIGPPGPNGEPG 110 GR G GP+ G GE GD G++G PG G G Sbjct: 972 PTGRDGVQGPVGLPGPAGPPGVAGEDGDKGEVGDPGQKGTKG 1013 Score = 73.9 bits (180), Expect = 1e-13 Identities = 40/93 (43%), Positives = 48/93 (51%), Gaps = 3/93 (3%) Query: 21 PSGHPQPAG---DDACSVQILVPGLKGDAGEKGDKGAPGRPGRVGPTGEKGDMGDKGQKG 77 P G+P P G D + G G G++G+ G PG+PG GPTGE G G G++G Sbjct: 1176 PKGNPGPVGFPGDPGPPGEGGPRGQDGAKGDRGEDGEPGQPGSPGPTGENGPPGPLGKRG 1235 Query: 78 SVGRHGKIGPIGSKGEKGDSGDIGPPGPNGEPG 110 G G G G KG KGD G IG PG G G Sbjct: 1236 PAGSPGSEGRQGGKGAKGDPGAIGAPGKTGPVG 1268 Score = 73.6 bits (179), Expect = 2e-13 Identities = 40/93 (43%), Positives = 50/93 (53%), Gaps = 6/93 (6%) Query: 21 PSGHPQPAGDDACSVQILVPGLKGDAGEKGDKGAPGRPGRVGP---TGEKGDMGDKGQKG 77 P G P P G D PG +G+ G +G G PG PG VGP GE G MG++G G Sbjct: 804 PKGPPGPPGKDGLPGH---PGQRGEVGFQGKTGPPGPPGVVGPQGAAGETGPMGERGHPG 860 Query: 78 SVGRHGKIGPIGSKGEKGDSGDIGPPGPNGEPG 110 G G+ G G+ G++G GD GPPG G+ G Sbjct: 861 PPGPPGEQGLPGTAGKEGTKGDPGPPGAPGKDG 893 Score = 72.0 bits (175), Expect = 5e-13 Identities = 40/92 (43%), Positives = 45/92 (48%), Gaps = 9/92 (9%) Query: 21 PSGHPQPAGDDACSVQILVPGLKGDAGEKGDKGAPGRPGRVGPTGEKGDMGDKGQKGSVG 80 P G PAG PG +G G KG KG PG G G TG G G G+ G G Sbjct: 1230 PLGKRGPAGS---------PGSEGRQGGKGAKGDPGAIGAPGKTGPVGPAGPAGKPGPDG 1280 Query: 81 RHGKIGPIGSKGEKGDSGDIGPPGPNGEPGLP 112 G G +G +G G +G GPPGP G PGLP Sbjct: 1281 LRGLPGSVGQQGRPGATGQAGPPGPVGPPGLP 1312 Score = 71.2 bits (173), Expect = 9e-13 Identities = 40/91 (43%), Positives = 46/91 (50%) Query: 22 SGHPQPAGDDACSVQILVPGLKGDAGEKGDKGAPGRPGRVGPTGEKGDMGDKGQKGSVGR 81 +G AG D PG+KGD G G G PG G G TG +G G G+ G G Sbjct: 448 AGRRGRAGADGARGMPGDPGVKGDRGFDGLPGLPGEKGHRGDTGAQGLPGPPGEDGERGD 507 Query: 82 HGKIGPIGSKGEKGDSGDIGPPGPNGEPGLP 112 G+IGP G GE G G +GP GP G PG P Sbjct: 508 DGEIGPRGLPGESGPRGLLGPKGPPGIPGPP 538 Score = 70.5 bits (171), Expect = 1e-12 Identities = 39/97 (40%), Positives = 49/97 (50%), Gaps = 6/97 (6%) Query: 21 PSGHPQPAGDDACSV------QILVPGLKGDAGEKGDKGAPGRPGRVGPTGEKGDMGDKG 74 P GH GD+ I + GL G +GEKG+ G G G GP G +G G G Sbjct: 1047 PQGHFGAKGDEGTRGFNGPPGPIGLQGLPGPSGEKGETGDVGPMGPPGPPGPRGPAGPNG 1106 Query: 75 QKGSVGRHGKIGPIGSKGEKGDSGDIGPPGPNGEPGL 111 G G G +G +G GEKG+ G+ G PG GEPG+ Sbjct: 1107 ADGPQGPPGGVGNLGPPGEKGEPGESGSPGIQGEPGV 1143 Score = 69.7 bits (169), Expect = 3e-12 Identities = 41/98 (41%), Positives = 52/98 (53%), Gaps = 15/98 (15%) Query: 21 PSGHPQPAGDDACSVQILVPGLKGDAGEKGDKGAPGRPGRVGPTGEKGDMGDKGQKGSVG 80 P G+P P G + GLKG GEKG+ G PG G +G G++G++G G + Sbjct: 627 PLGYPGPRGVKGVDG---IRGLKGHKGEKGEDGFPGFKGDIGVKGDRGEVGVPGSR---- 679 Query: 81 RHGKIGPIGSKGEKGDSGDIGPPGPNGE------PGLP 112 G+ GP G KG G +GD GPPG GE PGLP Sbjct: 680 --GEDGPEGPKGRTGPTGDPGPPGLMGEKGKLGVPGLP 715 Score = 68.9 bits (167), Expect = 4e-12 Identities = 38/89 (42%), Positives = 46/89 (51%) Query: 23 GHPQPAGDDACSVQILVPGLKGDAGEKGDKGAPGRPGRVGPTGEKGDMGDKGQKGSVGRH 82 G PAG + +PG G G KG++G G PG G GE+G G G G GR Sbjct: 890 GKDGPAGLRGFPGERGLPGTAGGPGLKGNEGPSGPPGPAGSPGERGAAGSGGPIGPPGRP 949 Query: 83 GKIGPIGSKGEKGDSGDIGPPGPNGEPGL 111 G GP G+ GEKG G+ GP GP G G+ Sbjct: 950 GPQGPPGAAGEKGVPGEKGPIGPTGRDGV 978 Score = 68.2 bits (165), Expect = 7e-12 Identities = 36/80 (45%), Positives = 48/80 (60%), Gaps = 6/80 (7%) Query: 39 VPGLKGDAGEKGDKGAPGRPGR---VGPTGEKGDMGDKGQKGSVGRHGKIGPIGSKGE-- 93 +PG +G G G KG PG PG+ G G++G++G +G+ G G G +GP G+ GE Sbjct: 792 LPGPQGPNGFPGPKGPPGPPGKDGLPGHPGQRGEVGFQGKTGPPGPPGVVGPQGAAGETG 851 Query: 94 -KGDSGDIGPPGPNGEPGLP 112 G+ G GPPGP GE GLP Sbjct: 852 PMGERGHPGPPGPPGEQGLP 871 Score = 67.8 bits (164), Expect = 1e-11 Identities = 39/89 (43%), Positives = 45/89 (50%), Gaps = 18/89 (20%) Query: 39 VPGLKGDAGEKGDKGAPGRPGRVGPTGEKGDMGDKGQKGSVGRHGKIGPIGSKGEKGDSG 98 +PGL G+ G +GD GA G PG P GE G+ GD G+ G G G+ GP G G KG G Sbjct: 477 LPGLPGEKGHRGDTGAQGLPG---PPGEDGERGDDGEIGPRGLPGESGPRGLLGPKGPPG 533 Query: 99 DIGPP---------------GPNGEPGLP 112 GPP GP GEPG P Sbjct: 534 IPGPPGVRGMDGPQGPKGSLGPQGEPGPP 562 Score = 67.8 bits (164), Expect = 1e-11 Identities = 41/101 (40%), Positives = 51/101 (50%), Gaps = 12/101 (11%) Query: 21 PSGHPQPAGDDACSVQILVPGLKGDAGEKGDKGAPGRPGRVGPTGEKGDMGDKGQKGSVG 80 P G GDD +I GL G++G +G G G PG GP G +G G +G KGS+G Sbjct: 498 PPGEDGERGDDG---EIGPRGLPGESGPRGLLGPKGPPGIPGPPGVRGMDGPQGPKGSLG 554 Query: 81 RHGKIGPIGSKGEKGDSGDIGP---------PGPNGEPGLP 112 G+ GP G +G G G GP GP G+PGLP Sbjct: 555 PQGEPGPPGQQGTPGTQGLPGPQGAIGPHGEKGPQGKPGLP 595 Score = 67.8 bits (164), Expect = 1e-11 Identities = 36/84 (42%), Positives = 43/84 (51%), Gaps = 9/84 (10%) Query: 40 PGLKGD---------AGEKGDKGAPGRPGRVGPTGEKGDMGDKGQKGSVGRHGKIGPIGS 90 PGLKG+ AG G++GA G G +GP G G G G G G G+ GPIG Sbjct: 913 PGLKGNEGPSGPPGPAGSPGERGAAGSGGPIGPPGRPGPQGPPGAAGEKGVPGEKGPIGP 972 Query: 91 KGEKGDSGDIGPPGPNGEPGLPCE 114 G G G +G PGP G PG+ E Sbjct: 973 TGRDGVQGPVGLPGPAGPPGVAGE 996 Score = 67.8 bits (164), Expect = 1e-11 Identities = 38/90 (42%), Positives = 44/90 (48%), Gaps = 12/90 (13%) Query: 21 PSGHPQPAGDDACSVQILVPGLKGDAGEKGDKGAPGRPGRVGPTGEKGDMGDKGQKGSVG 80 P G P GDD G KG+ G G G PG PG GP G+ G GD+G+ G G Sbjct: 1164 PPGPKGPTGDD---------GPKGNPGPVGFPGDPGPPGEGGPRGQDGAKGDRGEDGEPG 1214 Query: 81 RHGKIGPIGSKGEKGDSGDIGPPGPNGEPG 110 + G GP GE G G +G GP G PG Sbjct: 1215 QPGSPGP---TGENGPPGPLGKRGPAGSPG 1241 Score = 67.4 bits (163), Expect = 1e-11 Identities = 37/88 (42%), Positives = 41/88 (46%), Gaps = 6/88 (6%) Query: 23 GHPQPAGDDACSVQILVPGLKGDAGEKGDKGAPGRPGRVGPTGEKGDMGDKGQKGSVGRH 82 G P P G + PG KG G G G PG PG+ G G +G G G G VG Sbjct: 791 GLPGPQGPNG------FPGPKGPPGPPGKDGLPGHPGQRGEVGFQGKTGPPGPPGVVGPQ 844 Query: 83 GKIGPIGSKGEKGDSGDIGPPGPNGEPG 110 G G G GE+G G GPPG G PG Sbjct: 845 GAAGETGPMGERGHPGPPGPPGEQGLPG 872 Score = 67.4 bits (163), Expect = 1e-11 Identities = 37/90 (41%), Positives = 43/90 (47%) Query: 22 SGHPQPAGDDACSVQILVPGLKGDAGEKGDKGAPGRPGRVGPTGEKGDMGDKGQKGSVGR 81 +G P P G + G +G G KGD GA G PG+ GP G G G G G G Sbjct: 1225 NGPPGPLGKRGPAGSPGSEGRQGGKGAKGDPGAIGAPGKTGPVGPAGPAGKPGPDGLRGL 1284 Query: 82 HGKIGPIGSKGEKGDSGDIGPPGPNGEPGL 111 G +G G G G +G GP GP G PGL Sbjct: 1285 PGSVGQQGRPGATGQAGPPGPVGPPGLPGL 1314 Score = 67.0 bits (162), Expect = 2e-11 Identities = 42/110 (38%), Positives = 51/110 (46%), Gaps = 9/110 (8%) Query: 23 GHPQ------PAGDDACSVQILVPGLKGDAGEKGDKGAPGRPGRVGPTGEKGDMGDKGQK 76 GHP P G+ +PG +G G+KG+ G PG G +GP G G G G K Sbjct: 1325 GHPGLIGLIGPPGEQGEKGDRGLPGPQGSPGQKGEMGIPGASGPIGPGGPPGLPGPAGPK 1384 Query: 77 GSVGRHGKIGPIGSKGEKGDSGDIGPPGPNGEPGLPCECSQLRKAIGEMD 126 G+ G GP G KGEKG G G PGP GE P +K +D Sbjct: 1385 GA---KGATGPGGPKGEKGVQGPPGHPGPPGEVIQPLPIQMPKKTRRSVD 1431 Score = 66.2 bits (160), Expect = 3e-11 Identities = 41/100 (41%), Positives = 48/100 (48%), Gaps = 18/100 (18%) Query: 23 GHPQPAGDDACSVQILVPGLKGDAGEKGDKGAPGRP------------GRVGPTGEKGDM 70 GH G+D PG KGD G KGD+G G P GR GPTG+ G Sbjct: 647 GHKGEKGEDG------FPGFKGDIGVKGDRGEVGVPGSRGEDGPEGPKGRTGPTGDPGPP 700 Query: 71 GDKGQKGSVGRHGKIGPIGSKGEKGDSGDIGPPGPNGEPG 110 G G+KG +G G G G +G KG G G PG +GE G Sbjct: 701 GLMGEKGKLGVPGLPGYPGRQGPKGSLGFPGFPGASGEKG 740 Score = 65.5 bits (158), Expect = 5e-11 Identities = 37/92 (40%), Positives = 43/92 (46%), Gaps = 9/92 (9%) Query: 21 PSGHPQPAGDDACSVQILVPGLKGDAGEKGDKGAPGRPGRVGPTGEKGDMGDKGQKGSVG 80 P G P P G V G+ G G KG G G PG G G G G G +G++G Sbjct: 531 PPGIPGPPG---------VRGMDGPQGPKGSLGPQGEPGPPGQQGTPGTQGLPGPQGAIG 581 Query: 81 RHGKIGPIGSKGEKGDSGDIGPPGPNGEPGLP 112 HG+ GP G G G G GPPG G+ G P Sbjct: 582 PHGEKGPQGKPGLPGMPGSDGPPGHPGKEGPP 613 Score = 65.1 bits (157), Expect = 6e-11 Identities = 40/101 (39%), Positives = 48/101 (47%), Gaps = 18/101 (17%) Query: 22 SGHPQPAGDDACSVQILVPGLKGDAGEKGDKGA------------PGRPGRVGPTGEKGD 69 +G P P G PGLKG++G+ G +G GR GR G G +G Sbjct: 409 TGRPGPLGQPGS------PGLKGESGDLGPQGPRGPQGLTGPPGKAGRRGRAGADGARGM 462 Query: 70 MGDKGQKGSVGRHGKIGPIGSKGEKGDSGDIGPPGPNGEPG 110 GD G KG G G G G KG +GD+G G PGP GE G Sbjct: 463 PGDPGVKGDRGFDGLPGLPGEKGHRGDTGAQGLPGPPGEDG 503 Score = 64.7 bits (156), Expect = 8e-11 Identities = 40/100 (40%), Positives = 46/100 (46%), Gaps = 18/100 (18%) Query: 21 PSGHPQPAGDDACSVQILVPGLKGDAGEKGDKGAPGRPGRVGPTGEKGDMGD------KG 74 P G P G+ PG G G G +G PG G +GP GEKG G G Sbjct: 549 PKGSLGPQGE---------PGPPGQQGTPGTQGLPGPQGAIGPHGEKGPQGKPGLPGMPG 599 Query: 75 QKGSVGRHGKIGPIGSKGEKGDSGDIGP---PGPNGEPGL 111 G G GK GP G+KG +G SG GP PGP G G+ Sbjct: 600 SDGPPGHPGKEGPPGTKGNQGPSGPQGPLGYPGPRGVKGV 639 Score = 64.7 bits (156), Expect = 8e-11 Identities = 45/125 (36%), Positives = 52/125 (41%), Gaps = 30/125 (24%) Query: 18 SLLPSGHPQPAGDDACSVQILVPGLKGDAGEKGDKGA------PGRPGRVGPTGEKGDMG 71 SL P G P P G +PG +G G G+KG PG PG GP G G G Sbjct: 552 SLGPQGEPGPPGQQGTPGTQGLPGPQGAIGPHGEKGPQGKPGLPGMPGSDGPPGHPGKEG 611 Query: 72 DKGQKGSVGRHGKIGPI------------------GSKGEKGD------SGDIGPPGPNG 107 G KG+ G G GP+ G KGEKG+ GDIG G G Sbjct: 612 PPGTKGNQGPSGPQGPLGYPGPRGVKGVDGIRGLKGHKGEKGEDGFPGFKGDIGVKGDRG 671 Query: 108 EPGLP 112 E G+P Sbjct: 672 EVGVP 676 Score = 64.7 bits (156), Expect = 8e-11 Identities = 38/90 (42%), Positives = 42/90 (46%), Gaps = 9/90 (10%) Query: 21 PSGHPQPAGDDACSVQILVPGLKGDAGEKGDKGAPGRPGRVGPTGEKGDMGDKGQKGSVG 80 P GHP G PG KG+ G G +G G PG G G G G KG KG G Sbjct: 603 PPGHPGKEGP---------PGTKGNQGPSGPQGPLGYPGPRGVKGVDGIRGLKGHKGEKG 653 Query: 81 RHGKIGPIGSKGEKGDSGDIGPPGPNGEPG 110 G G G G KGD G++G PG GE G Sbjct: 654 EDGFPGFKGDIGVKGDRGEVGVPGSRGEDG 683 Score = 64.7 bits (156), Expect = 8e-11 Identities = 38/93 (40%), Positives = 45/93 (48%), Gaps = 9/93 (9%) Query: 21 PSGHPQPAGDDACSVQILVPGLKGDAGE---KGDKGAPGRPGRVGPTGEKGDMGDKGQKG 77 P G P AG D PG +G G KGD+G G G GP G +G G G+KG Sbjct: 1029 PVGQPGAAGADG------EPGARGPQGHFGAKGDEGTRGFNGPPGPIGLQGLPGPSGEKG 1082 Query: 78 SVGRHGKIGPIGSKGEKGDSGDIGPPGPNGEPG 110 G G +GP G G +G +G G GP G PG Sbjct: 1083 ETGDVGPMGPPGPPGPRGPAGPNGADGPQGPPG 1115 Score = 64.3 bits (155), Expect = 1e-10 Identities = 35/76 (46%), Positives = 39/76 (51%), Gaps = 3/76 (3%) Query: 40 PGLKGDAGEKGDKGAPGR---PGRVGPTGEKGDMGDKGQKGSVGRHGKIGPIGSKGEKGD 96 PG KG G+ G KG PG PG GP GE G G G KG G G+ G GS G G+ Sbjct: 1165 PGPKGPTGDDGPKGNPGPVGFPGDPGPPGEGGPRGQDGAKGDRGEDGEPGQPGSPGPTGE 1224 Query: 97 SGDIGPPGPNGEPGLP 112 +G GP G G G P Sbjct: 1225 NGPPGPLGKRGPAGSP 1240 Score = 63.9 bits (154), Expect = 1e-10 Identities = 35/79 (44%), Positives = 40/79 (50%), Gaps = 9/79 (11%) Query: 41 GLKGDAGEKGDKGAPGRPGRVGPTGEKGDM---------GDKGQKGSVGRHGKIGPIGSK 91 G G AG +G GA G G G G KGD G+KG +G G G GP G Sbjct: 443 GPPGKAGRRGRAGADGARGMPGDPGVKGDRGFDGLPGLPGEKGHRGDTGAQGLPGPPGED 502 Query: 92 GEKGDSGDIGPPGPNGEPG 110 GE+GD G+IGP G GE G Sbjct: 503 GERGDDGEIGPRGLPGESG 521 Score = 63.9 bits (154), Expect = 1e-10 Identities = 30/73 (41%), Positives = 38/73 (52%) Query: 40 PGLKGDAGEKGDKGAPGRPGRVGPTGEKGDMGDKGQKGSVGRHGKIGPIGSKGEKGDSGD 99 PG G +GEKG +G G+ G G G G G +G +G+ G+ G G G G G G+ Sbjct: 730 PGFPGASGEKGARGLSGKSGPRGERGPTGPRGQRGPRGATGKSGAKGTSGGDGPHGPPGE 789 Query: 100 IGPPGPNGEPGLP 112 G PGP G G P Sbjct: 790 RGLPGPQGPNGFP 802 Score = 63.2 bits (152), Expect = 2e-10 Identities = 31/70 (44%), Positives = 38/70 (54%) Query: 41 GLKGDAGEKGDKGAPGRPGRVGPTGEKGDMGDKGQKGSVGRHGKIGPIGSKGEKGDSGDI 100 GL G +G +G++G G G+ GP G G G KG G G HG G G G +G +G Sbjct: 743 GLSGKSGPRGERGPTGPRGQRGPRGATGKSGAKGTSGGDGPHGPPGERGLPGPQGPNGFP 802 Query: 101 GPPGPNGEPG 110 GP GP G PG Sbjct: 803 GPKGPPGPPG 812 Score = 63.2 bits (152), Expect = 2e-10 Identities = 36/97 (37%), Positives = 46/97 (47%), Gaps = 9/97 (9%) Query: 23 GHPQPAGDDACSVQILVPGLKGDAGEKGDKGAPGRPGRVGPTGEKGDMGDKGQKGSVGRH 82 G P P+G+ + + G G G +G G G G GP G G++G G+KG G Sbjct: 1073 GLPGPSGEKGETGDVGPMGPPGPPGPRGPAGPNGADGPQGPPGGVGNLGPPGEKGEPGES 1132 Query: 83 GK---------IGPIGSKGEKGDSGDIGPPGPNGEPG 110 G GP G +GEKG+SG G PGP G G Sbjct: 1133 GSPGIQGEPGVKGPRGERGEKGESGQPGEPGPPGPKG 1169 Score = 62.4 bits (150), Expect = 4e-10 Identities = 37/92 (40%), Positives = 45/92 (48%), Gaps = 3/92 (3%) Query: 21 PSGHPQPAGDDACSVQILVPGLKGDAGEKGDKGAPGRPGRVGPTGEKGDMGDKGQKGSVG 80 PSG GD PG +G AG G G G PG VG G G+ G+ G+ GS G Sbjct: 1077 PSGEKGETGDVGPMGPPGPPGPRGPAGPNGADGPQGPPGGVGNLGPPGEKGEPGESGSPG 1136 Query: 81 RHGKIGPIGSKGEKGDSGDIGPPGPNGEPGLP 112 G+ G KG +G+ G+ G G GEPG P Sbjct: 1137 IQGEPGV---KGPRGERGEKGESGQPGEPGPP 1165 Score = 62.0 bits (149), Expect = 5e-10 Identities = 37/90 (41%), Positives = 40/90 (44%), Gaps = 6/90 (6%) Query: 21 PSGHPQPAGDDACSVQILVPGLKGDAGEKGDKGAPGRPGRVGPTGEKGDMGDKGQKGSVG 80 P G P G S G KG +G G G PG G GP G G G KG G G Sbjct: 759 PRGQRGPRGATGKS------GAKGTSGGDGPHGPPGERGLPGPQGPNGFPGPKGPPGPPG 812 Query: 81 RHGKIGPIGSKGEKGDSGDIGPPGPNGEPG 110 + G G G +GE G G GPPGP G G Sbjct: 813 KDGLPGHPGQRGEVGFQGKTGPPGPPGVVG 842 Score = 61.2 bits (147), Expect = 9e-10 Identities = 36/99 (36%), Positives = 41/99 (41%), Gaps = 9/99 (9%) Query: 21 PSGHPQPAGDDACSVQILVPGLKGDAGEKGDKGAPGRPGRVGPTGEKGDMGDKGQ----- 75 P G P G + + G +G G G G G PG G G KGD G G Sbjct: 834 PPGPPGVVGPQGAAGETGPMGERGHPGPPGPPGEQGLPGTAGKEGTKGDPGPPGAPGKDG 893 Query: 76 ----KGSVGRHGKIGPIGSKGEKGDSGDIGPPGPNGEPG 110 +G G G G G G KG+ G GPPGP G PG Sbjct: 894 PAGLRGFPGERGLPGTAGGPGLKGNEGPSGPPGPAGSPG 932 Score = 60.8 bits (146), Expect = 1e-09 Identities = 31/74 (41%), Positives = 38/74 (51%) Query: 41 GLKGDAGEKGDKGAPGRPGRVGPTGEKGDMGDKGQKGSVGRHGKIGPIGSKGEKGDSGDI 100 G G G+ G G G G +GP G +G G G G GR G+ G G++G GD G Sbjct: 410 GRPGPLGQPGSPGLKGESGDLGPQGPRGPQGLTGPPGKAGRRGRAGADGARGMPGDPGVK 469 Query: 101 GPPGPNGEPGLPCE 114 G G +G PGLP E Sbjct: 470 GDRGFDGLPGLPGE 483 Score = 57.8 bits (138), Expect = 1e-08 Identities = 35/84 (41%), Positives = 43/84 (51%), Gaps = 9/84 (10%) Query: 36 QILVPGLKGDAGEKGDKGAPGRPGRVGP---TGEKGDMGDKGQKGSVGRHGKIGPI---- 88 ++ VPG +G+ G +G KG G G GP GEKG +G G G GR G G + Sbjct: 672 EVGVPGSRGEDGPEGPKGRTGPTGDPGPPGLMGEKGKLGVPGLPGYPGRQGPKGSLGFPG 731 Query: 89 --GSKGEKGDSGDIGPPGPNGEPG 110 G+ GEKG G G GP GE G Sbjct: 732 FPGASGEKGARGLSGKSGPRGERG 755 Score = 57.4 bits (137), Expect = 1e-08 Identities = 40/120 (33%), Positives = 49/120 (40%), Gaps = 40/120 (33%) Query: 23 GHPQPAGDDACSVQILVPGLKGDAGEKGDKGAPGRPGRVGPT-----------GEKGDM- 70 G+P P GD PG +G G G G+ G PG G + G+KG + Sbjct: 331 GNPGPVGD---------PGERGPPGRAGLPGSDGAPGPPGTSLMLPFRFGSGGGDKGPVV 381 Query: 71 -------------------GDKGQKGSVGRHGKIGPIGSKGEKGDSGDIGPPGPNGEPGL 111 G G G GR G +G GS G KG+SGD+GP GP G GL Sbjct: 382 AAQEAQAQAILQQARLALRGPPGPMGYTGRPGPLGQPGSPGLKGESGDLGPQGPRGPQGL 441 Score = 56.2 bits (134), Expect = 3e-08 Identities = 29/70 (41%), Positives = 37/70 (52%) Query: 42 LKGDAGEKGDKGAPGRPGRVGPTGEKGDMGDKGQKGSVGRHGKIGPIGSKGEKGDSGDIG 101 L+G G G G PG G+ G G KG+ GD G +G G G GP G G +G +G G Sbjct: 399 LRGPPGPMGYTGRPGPLGQPGSPGLKGESGDLGPQGPRGPQGLTGPPGKAGRRGRAGADG 458 Query: 102 PPGPNGEPGL 111 G G+PG+ Sbjct: 459 ARGMPGDPGV 468 Score = 54.7 bits (130), Expect = 8e-08 Identities = 36/97 (37%), Positives = 45/97 (46%), Gaps = 7/97 (7%) Query: 22 SGHPQPAGDDACSVQILVPGLK----GDAGEKGDKGAPG--RPGRVGPTGEKGDMGDKGQ 75 S P P ++ L+P L+ G G KG+KG P PG + G G G G Sbjct: 265 SQDPTPGEEEEILESSLLPPLEEAAHGPRGLKGEKGEPAVLEPGML-VEGPPGPEGPAGL 323 Query: 76 KGSVGRHGKIGPIGSKGEKGDSGDIGPPGPNGEPGLP 112 G G G GP+G GE+G G G PG +G PG P Sbjct: 324 IGPPGIQGNPGPVGDPGERGPPGRAGLPGSDGAPGPP 360 Score = 46.2 bits (108), Expect = 3e-05 Identities = 33/104 (31%), Positives = 39/104 (37%), Gaps = 28/104 (26%) Query: 37 ILVPGLKGDAGEKGDKGAPGRPGRVGPTGEKGDMGDKGQKGSVGRHGKIGPIGSK----- 91 +LV G G G G G PG G GP G+ G+ G G+ G G G GP G+ Sbjct: 309 MLVEGPPGPEGPAGLIGPPGIQGNPGPVGDPGERGPPGRAGLPGSDGAPGPPGTSLMLPF 368 Query: 92 ---GEKGDSGDI--------------------GPPGPNGEPGLP 112 GD G + GPPGP G G P Sbjct: 369 RFGSGGGDKGPVVAAQEAQAQAILQQARLALRGPPGPMGYTGRP 412 Score = 32.3 bits (72), Expect = 0.45 Identities = 17/41 (41%), Positives = 19/41 (46%) Query: 21 PSGHPQPAGDDACSVQILVPGLKGDAGEKGDKGAPGRPGRV 61 P G P PAG G KG+ G +G G PG PG V Sbjct: 1374 PPGLPGPAGPKGAKGATGPGGPKGEKGVQGPPGHPGPPGEV 1414 >gi|111118968 collagen, type XI, alpha 2 isoform 3 preproprotein [Homo sapiens] Length = 1629 Score = 83.6 bits (205), Expect = 2e-16 Identities = 45/111 (40%), Positives = 59/111 (53%), Gaps = 21/111 (18%) Query: 21 PSGHPQPAGDDACSVQILVPGLKGDAGEKGDKGAPGRPGRVGPTGE-------------- 66 P+G P AG+D ++ PG KG G KG+ G PG PG +GP G+ Sbjct: 966 PAGPPGVAGEDGDKGEVGDPGQKGTKGNKGEHGPPGPPGPIGPVGQPGAAGADGEPGARG 1025 Query: 67 -KGDMGDKGQKGSVGRHGKIGPI------GSKGEKGDSGDIGPPGPNGEPG 110 +G G KG +G+ G +G GPI G GEKG++GD+GP GP G PG Sbjct: 1026 PQGHFGAKGDEGTRGFNGPPGPIGLQGLPGPSGEKGETGDVGPMGPPGPPG 1076 Score = 80.5 bits (197), Expect = 1e-15 Identities = 43/91 (47%), Positives = 52/91 (57%), Gaps = 12/91 (13%) Query: 22 SGHPQPAGDDACSVQILVPGLKGDAGEKGDKGAPGRPGRVGPTGEKGDMGDKGQKGSVGR 81 +G P P G +PGL+GDAG KG+KG PG G +GP GE+G+ GD+G G G Sbjct: 1279 AGPPGPVGPPG------LPGLRGDAGAKGEKGHPGLIGLIGPPGEQGEKGDRGLPGPQGS 1332 Query: 82 HGKIGPIGSKGEKGDSGDIGPPGPNGEPGLP 112 G+ KGE G G GP GP G PGLP Sbjct: 1333 PGQ------KGEMGIPGASGPIGPGGPPGLP 1357 Score = 78.6 bits (192), Expect = 5e-15 Identities = 39/90 (43%), Positives = 47/90 (52%) Query: 21 PSGHPQPAGDDACSVQILVPGLKGDAGEKGDKGAPGRPGRVGPTGEKGDMGDKGQKGSVG 80 P+G P G + PG KG+ GE G G G PG GP GE+G+ G+ GQ G G Sbjct: 1083 PNGADGPQGPPGGVGNLGPPGEKGEPGESGSPGIQGEPGVKGPRGERGEKGESGQPGEPG 1142 Query: 81 RHGKIGPIGSKGEKGDSGDIGPPGPNGEPG 110 G GP G G KG+ G +G PG G PG Sbjct: 1143 PPGPKGPTGDDGPKGNPGPVGFPGDPGPPG 1172 Score = 78.2 bits (191), Expect = 7e-15 Identities = 40/90 (44%), Positives = 47/90 (52%) Query: 23 GHPQPAGDDACSVQILVPGLKGDAGEKGDKGAPGRPGRVGPTGEKGDMGDKGQKGSVGRH 82 G P +G + V G +G+ GEKG+ G PG PG GP G GD G KG G VG Sbjct: 1106 GEPGESGSPGIQGEPGVKGPRGERGEKGESGQPGEPGPPGPKGPTGDDGPKGNPGPVGFP 1165 Query: 83 GKIGPIGSKGEKGDSGDIGPPGPNGEPGLP 112 G GP G G +G G G G +GEPG P Sbjct: 1166 GDPGPPGEGGPRGQDGAKGDRGEDGEPGQP 1195 Score = 76.3 bits (186), Expect = 3e-14 Identities = 42/90 (46%), Positives = 46/90 (51%), Gaps = 6/90 (6%) Query: 21 PSGHPQPAGDDACSVQILVPGLKGDAGEKGDKGAPGRPGRVGPTGEKGDMGDKGQKGSVG 80 P+G P P G +PG G G G G G PG VGP G G GD G KG G Sbjct: 1251 PAGKPGPDGLRG------LPGSVGQQGRPGATGQAGPPGPVGPPGLPGLRGDAGAKGEKG 1304 Query: 81 RHGKIGPIGSKGEKGDSGDIGPPGPNGEPG 110 G IG IG GE+G+ GD G PGP G PG Sbjct: 1305 HPGLIGLIGPPGEQGEKGDRGLPGPQGSPG 1334 Score = 75.9 bits (185), Expect = 4e-14 Identities = 42/97 (43%), Positives = 51/97 (52%), Gaps = 12/97 (12%) Query: 23 GHPQPAGDDACSVQILVPGLKGDAGEKGDKGAPGRPGRVGPTGEKGDMGDKGQ------- 75 GHP P G + +PG G G KGD G PG PG+ GP G +G G++G Sbjct: 836 GHPGPPGPPG---EQGLPGTAGKEGTKGDPGPPGAPGKDGPAGLRGFPGERGLPGTAGGP 892 Query: 76 --KGSVGRHGKIGPIGSKGEKGDSGDIGPPGPNGEPG 110 KG+ G G GP GS GE+G +G GP GP G PG Sbjct: 893 GLKGNEGPSGPPGPAGSPGERGAAGSGGPIGPPGRPG 929 Score = 75.1 bits (183), Expect = 6e-14 Identities = 40/90 (44%), Positives = 46/90 (51%) Query: 21 PSGHPQPAGDDACSVQILVPGLKGDAGEKGDKGAPGRPGRVGPTGEKGDMGDKGQKGSVG 80 P G P P G + + VPG KG G G G G G GP G G G+ G KG VG Sbjct: 924 PPGRPGPQGPPGAAGEKGVPGEKGPIGPTGRDGVQGPVGLPGPAGPPGVAGEDGDKGEVG 983 Query: 81 RHGKIGPIGSKGEKGDSGDIGPPGPNGEPG 110 G+ G G+KGE G G GP GP G+PG Sbjct: 984 DPGQKGTKGNKGEHGPPGPPGPIGPVGQPG 1013 Score = 75.1 bits (183), Expect = 6e-14 Identities = 42/95 (44%), Positives = 50/95 (52%), Gaps = 3/95 (3%) Query: 21 PSGHPQPAGDDACSVQILVPGLKGDAGEKGDKGAPGR---PGRVGPTGEKGDMGDKGQKG 77 P G PAG + PG G+ G G+KG PG PG G G KG G++G+KG Sbjct: 1074 PPGPRGPAGPNGADGPQGPPGGVGNLGPPGEKGEPGESGSPGIQGEPGVKGPRGERGEKG 1133 Query: 78 SVGRHGKIGPIGSKGEKGDSGDIGPPGPNGEPGLP 112 G+ G+ GP G KG GD G G PGP G PG P Sbjct: 1134 ESGQPGEPGPPGPKGPTGDDGPKGNPGPVGFPGDP 1168 Score = 74.7 bits (182), Expect = 8e-14 Identities = 44/101 (43%), Positives = 51/101 (50%), Gaps = 9/101 (8%) Query: 21 PSGHPQPAGDDACSVQILVPGLKGDAGEKGDKGAPGRPGRVGPTGEKGDMGDKGQKGSVG 80 P+G P P G ++ VPGL G G +G KG+ G PG G +GEKG G G+ G G Sbjct: 672 PTGDPGPPGLMGEKGKLGVPGLPGYPGRQGPKGSLGFPGFPGASGEKGARGLSGKSGPRG 731 Query: 81 RHGKIGP---------IGSKGEKGDSGDIGPPGPNGEPGLP 112 G GP G G KG SG GP GP GE GLP Sbjct: 732 ERGPTGPRGQRGPRGATGKSGAKGTSGGDGPHGPPGERGLP 772 Score = 74.3 bits (181), Expect = 1e-13 Identities = 45/102 (44%), Positives = 50/102 (49%), Gaps = 21/102 (20%) Query: 21 PSGHPQPAGDDACSVQILVPGLKGDAGEKGDKGAPGRPGRVGP---TGEKGDMGDKGQKG 77 PSG P PAG PG +G AG G G PGRPG GP GEKG G+KG G Sbjct: 900 PSGPPGPAGS---------PGERGAAGSGGPIGPPGRPGPQGPPGAAGEKGVPGEKGPIG 950 Query: 78 SVGRHGKIGPI---------GSKGEKGDSGDIGPPGPNGEPG 110 GR G GP+ G GE GD G++G PG G G Sbjct: 951 PTGRDGVQGPVGLPGPAGPPGVAGEDGDKGEVGDPGQKGTKG 992 Score = 73.9 bits (180), Expect = 1e-13 Identities = 40/93 (43%), Positives = 48/93 (51%), Gaps = 3/93 (3%) Query: 21 PSGHPQPAG---DDACSVQILVPGLKGDAGEKGDKGAPGRPGRVGPTGEKGDMGDKGQKG 77 P G+P P G D + G G G++G+ G PG+PG GPTGE G G G++G Sbjct: 1155 PKGNPGPVGFPGDPGPPGEGGPRGQDGAKGDRGEDGEPGQPGSPGPTGENGPPGPLGKRG 1214 Query: 78 SVGRHGKIGPIGSKGEKGDSGDIGPPGPNGEPG 110 G G G G KG KGD G IG PG G G Sbjct: 1215 PAGSPGSEGRQGGKGAKGDPGAIGAPGKTGPVG 1247 Score = 73.6 bits (179), Expect = 2e-13 Identities = 40/93 (43%), Positives = 50/93 (53%), Gaps = 6/93 (6%) Query: 21 PSGHPQPAGDDACSVQILVPGLKGDAGEKGDKGAPGRPGRVGP---TGEKGDMGDKGQKG 77 P G P P G D PG +G+ G +G G PG PG VGP GE G MG++G G Sbjct: 783 PKGPPGPPGKDGLPGH---PGQRGEVGFQGKTGPPGPPGVVGPQGAAGETGPMGERGHPG 839 Query: 78 SVGRHGKIGPIGSKGEKGDSGDIGPPGPNGEPG 110 G G+ G G+ G++G GD GPPG G+ G Sbjct: 840 PPGPPGEQGLPGTAGKEGTKGDPGPPGAPGKDG 872 Score = 72.0 bits (175), Expect = 5e-13 Identities = 40/92 (43%), Positives = 45/92 (48%), Gaps = 9/92 (9%) Query: 21 PSGHPQPAGDDACSVQILVPGLKGDAGEKGDKGAPGRPGRVGPTGEKGDMGDKGQKGSVG 80 P G PAG PG +G G KG KG PG G G TG G G G+ G G Sbjct: 1209 PLGKRGPAGS---------PGSEGRQGGKGAKGDPGAIGAPGKTGPVGPAGPAGKPGPDG 1259 Query: 81 RHGKIGPIGSKGEKGDSGDIGPPGPNGEPGLP 112 G G +G +G G +G GPPGP G PGLP Sbjct: 1260 LRGLPGSVGQQGRPGATGQAGPPGPVGPPGLP 1291 Score = 71.2 bits (173), Expect = 9e-13 Identities = 40/91 (43%), Positives = 46/91 (50%) Query: 22 SGHPQPAGDDACSVQILVPGLKGDAGEKGDKGAPGRPGRVGPTGEKGDMGDKGQKGSVGR 81 +G AG D PG+KGD G G G PG G G TG +G G G+ G G Sbjct: 427 AGRRGRAGADGARGMPGDPGVKGDRGFDGLPGLPGEKGHRGDTGAQGLPGPPGEDGERGD 486 Query: 82 HGKIGPIGSKGEKGDSGDIGPPGPNGEPGLP 112 G+IGP G GE G G +GP GP G PG P Sbjct: 487 DGEIGPRGLPGESGPRGLLGPKGPPGIPGPP 517 Score = 70.5 bits (171), Expect = 1e-12 Identities = 39/97 (40%), Positives = 49/97 (50%), Gaps = 6/97 (6%) Query: 21 PSGHPQPAGDDACSV------QILVPGLKGDAGEKGDKGAPGRPGRVGPTGEKGDMGDKG 74 P GH GD+ I + GL G +GEKG+ G G G GP G +G G G Sbjct: 1026 PQGHFGAKGDEGTRGFNGPPGPIGLQGLPGPSGEKGETGDVGPMGPPGPPGPRGPAGPNG 1085 Query: 75 QKGSVGRHGKIGPIGSKGEKGDSGDIGPPGPNGEPGL 111 G G G +G +G GEKG+ G+ G PG GEPG+ Sbjct: 1086 ADGPQGPPGGVGNLGPPGEKGEPGESGSPGIQGEPGV 1122 Score = 69.7 bits (169), Expect = 3e-12 Identities = 41/98 (41%), Positives = 52/98 (53%), Gaps = 15/98 (15%) Query: 21 PSGHPQPAGDDACSVQILVPGLKGDAGEKGDKGAPGRPGRVGPTGEKGDMGDKGQKGSVG 80 P G+P P G + GLKG GEKG+ G PG G +G G++G++G G + Sbjct: 606 PLGYPGPRGVKGVDG---IRGLKGHKGEKGEDGFPGFKGDIGVKGDRGEVGVPGSR---- 658 Query: 81 RHGKIGPIGSKGEKGDSGDIGPPGPNGE------PGLP 112 G+ GP G KG G +GD GPPG GE PGLP Sbjct: 659 --GEDGPEGPKGRTGPTGDPGPPGLMGEKGKLGVPGLP 694 Score = 68.9 bits (167), Expect = 4e-12 Identities = 38/89 (42%), Positives = 46/89 (51%) Query: 23 GHPQPAGDDACSVQILVPGLKGDAGEKGDKGAPGRPGRVGPTGEKGDMGDKGQKGSVGRH 82 G PAG + +PG G G KG++G G PG G GE+G G G G GR Sbjct: 869 GKDGPAGLRGFPGERGLPGTAGGPGLKGNEGPSGPPGPAGSPGERGAAGSGGPIGPPGRP 928 Query: 83 GKIGPIGSKGEKGDSGDIGPPGPNGEPGL 111 G GP G+ GEKG G+ GP GP G G+ Sbjct: 929 GPQGPPGAAGEKGVPGEKGPIGPTGRDGV 957 Score = 68.2 bits (165), Expect = 7e-12 Identities = 36/80 (45%), Positives = 48/80 (60%), Gaps = 6/80 (7%) Query: 39 VPGLKGDAGEKGDKGAPGRPGR---VGPTGEKGDMGDKGQKGSVGRHGKIGPIGSKGE-- 93 +PG +G G G KG PG PG+ G G++G++G +G+ G G G +GP G+ GE Sbjct: 771 LPGPQGPNGFPGPKGPPGPPGKDGLPGHPGQRGEVGFQGKTGPPGPPGVVGPQGAAGETG 830 Query: 94 -KGDSGDIGPPGPNGEPGLP 112 G+ G GPPGP GE GLP Sbjct: 831 PMGERGHPGPPGPPGEQGLP 850 Score = 67.8 bits (164), Expect = 1e-11 Identities = 39/89 (43%), Positives = 45/89 (50%), Gaps = 18/89 (20%) Query: 39 VPGLKGDAGEKGDKGAPGRPGRVGPTGEKGDMGDKGQKGSVGRHGKIGPIGSKGEKGDSG 98 +PGL G+ G +GD GA G PG P GE G+ GD G+ G G G+ GP G G KG G Sbjct: 456 LPGLPGEKGHRGDTGAQGLPG---PPGEDGERGDDGEIGPRGLPGESGPRGLLGPKGPPG 512 Query: 99 DIGPP---------------GPNGEPGLP 112 GPP GP GEPG P Sbjct: 513 IPGPPGVRGMDGPQGPKGSLGPQGEPGPP 541 Score = 67.8 bits (164), Expect = 1e-11 Identities = 41/101 (40%), Positives = 51/101 (50%), Gaps = 12/101 (11%) Query: 21 PSGHPQPAGDDACSVQILVPGLKGDAGEKGDKGAPGRPGRVGPTGEKGDMGDKGQKGSVG 80 P G GDD +I GL G++G +G G G PG GP G +G G +G KGS+G Sbjct: 477 PPGEDGERGDDG---EIGPRGLPGESGPRGLLGPKGPPGIPGPPGVRGMDGPQGPKGSLG 533 Query: 81 RHGKIGPIGSKGEKGDSGDIGP---------PGPNGEPGLP 112 G+ GP G +G G G GP GP G+PGLP Sbjct: 534 PQGEPGPPGQQGTPGTQGLPGPQGAIGPHGEKGPQGKPGLP 574 Score = 67.8 bits (164), Expect = 1e-11 Identities = 36/84 (42%), Positives = 43/84 (51%), Gaps = 9/84 (10%) Query: 40 PGLKGD---------AGEKGDKGAPGRPGRVGPTGEKGDMGDKGQKGSVGRHGKIGPIGS 90 PGLKG+ AG G++GA G G +GP G G G G G G G+ GPIG Sbjct: 892 PGLKGNEGPSGPPGPAGSPGERGAAGSGGPIGPPGRPGPQGPPGAAGEKGVPGEKGPIGP 951 Query: 91 KGEKGDSGDIGPPGPNGEPGLPCE 114 G G G +G PGP G PG+ E Sbjct: 952 TGRDGVQGPVGLPGPAGPPGVAGE 975 Score = 67.8 bits (164), Expect = 1e-11 Identities = 38/90 (42%), Positives = 44/90 (48%), Gaps = 12/90 (13%) Query: 21 PSGHPQPAGDDACSVQILVPGLKGDAGEKGDKGAPGRPGRVGPTGEKGDMGDKGQKGSVG 80 P G P GDD G KG+ G G G PG PG GP G+ G GD+G+ G G Sbjct: 1143 PPGPKGPTGDD---------GPKGNPGPVGFPGDPGPPGEGGPRGQDGAKGDRGEDGEPG 1193 Query: 81 RHGKIGPIGSKGEKGDSGDIGPPGPNGEPG 110 + G GP GE G G +G GP G PG Sbjct: 1194 QPGSPGP---TGENGPPGPLGKRGPAGSPG 1220 Score = 67.4 bits (163), Expect = 1e-11 Identities = 37/88 (42%), Positives = 41/88 (46%), Gaps = 6/88 (6%) Query: 23 GHPQPAGDDACSVQILVPGLKGDAGEKGDKGAPGRPGRVGPTGEKGDMGDKGQKGSVGRH 82 G P P G + PG KG G G G PG PG+ G G +G G G G VG Sbjct: 770 GLPGPQGPNG------FPGPKGPPGPPGKDGLPGHPGQRGEVGFQGKTGPPGPPGVVGPQ 823 Query: 83 GKIGPIGSKGEKGDSGDIGPPGPNGEPG 110 G G G GE+G G GPPG G PG Sbjct: 824 GAAGETGPMGERGHPGPPGPPGEQGLPG 851 Score = 67.4 bits (163), Expect = 1e-11 Identities = 37/90 (41%), Positives = 43/90 (47%) Query: 22 SGHPQPAGDDACSVQILVPGLKGDAGEKGDKGAPGRPGRVGPTGEKGDMGDKGQKGSVGR 81 +G P P G + G +G G KGD GA G PG+ GP G G G G G G Sbjct: 1204 NGPPGPLGKRGPAGSPGSEGRQGGKGAKGDPGAIGAPGKTGPVGPAGPAGKPGPDGLRGL 1263 Query: 82 HGKIGPIGSKGEKGDSGDIGPPGPNGEPGL 111 G +G G G G +G GP GP G PGL Sbjct: 1264 PGSVGQQGRPGATGQAGPPGPVGPPGLPGL 1293 Score = 67.0 bits (162), Expect = 2e-11 Identities = 42/110 (38%), Positives = 51/110 (46%), Gaps = 9/110 (8%) Query: 23 GHPQ------PAGDDACSVQILVPGLKGDAGEKGDKGAPGRPGRVGPTGEKGDMGDKGQK 76 GHP P G+ +PG +G G+KG+ G PG G +GP G G G G K Sbjct: 1304 GHPGLIGLIGPPGEQGEKGDRGLPGPQGSPGQKGEMGIPGASGPIGPGGPPGLPGPAGPK 1363 Query: 77 GSVGRHGKIGPIGSKGEKGDSGDIGPPGPNGEPGLPCECSQLRKAIGEMD 126 G+ G GP G KGEKG G G PGP GE P +K +D Sbjct: 1364 GA---KGATGPGGPKGEKGVQGPPGHPGPPGEVIQPLPIQMPKKTRRSVD 1410 Score = 66.2 bits (160), Expect = 3e-11 Identities = 41/100 (41%), Positives = 48/100 (48%), Gaps = 18/100 (18%) Query: 23 GHPQPAGDDACSVQILVPGLKGDAGEKGDKGAPGRP------------GRVGPTGEKGDM 70 GH G+D PG KGD G KGD+G G P GR GPTG+ G Sbjct: 626 GHKGEKGEDG------FPGFKGDIGVKGDRGEVGVPGSRGEDGPEGPKGRTGPTGDPGPP 679 Query: 71 GDKGQKGSVGRHGKIGPIGSKGEKGDSGDIGPPGPNGEPG 110 G G+KG +G G G G +G KG G G PG +GE G Sbjct: 680 GLMGEKGKLGVPGLPGYPGRQGPKGSLGFPGFPGASGEKG 719 Score = 65.5 bits (158), Expect = 5e-11 Identities = 37/92 (40%), Positives = 43/92 (46%), Gaps = 9/92 (9%) Query: 21 PSGHPQPAGDDACSVQILVPGLKGDAGEKGDKGAPGRPGRVGPTGEKGDMGDKGQKGSVG 80 P G P P G V G+ G G KG G G PG G G G G G +G++G Sbjct: 510 PPGIPGPPG---------VRGMDGPQGPKGSLGPQGEPGPPGQQGTPGTQGLPGPQGAIG 560 Query: 81 RHGKIGPIGSKGEKGDSGDIGPPGPNGEPGLP 112 HG+ GP G G G G GPPG G+ G P Sbjct: 561 PHGEKGPQGKPGLPGMPGSDGPPGHPGKEGPP 592 Score = 65.1 bits (157), Expect = 6e-11 Identities = 40/101 (39%), Positives = 48/101 (47%), Gaps = 18/101 (17%) Query: 22 SGHPQPAGDDACSVQILVPGLKGDAGEKGDKGA------------PGRPGRVGPTGEKGD 69 +G P P G PGLKG++G+ G +G GR GR G G +G Sbjct: 388 TGRPGPLGQPGS------PGLKGESGDLGPQGPRGPQGLTGPPGKAGRRGRAGADGARGM 441 Query: 70 MGDKGQKGSVGRHGKIGPIGSKGEKGDSGDIGPPGPNGEPG 110 GD G KG G G G G KG +GD+G G PGP GE G Sbjct: 442 PGDPGVKGDRGFDGLPGLPGEKGHRGDTGAQGLPGPPGEDG 482 Score = 64.7 bits (156), Expect = 8e-11 Identities = 40/100 (40%), Positives = 46/100 (46%), Gaps = 18/100 (18%) Query: 21 PSGHPQPAGDDACSVQILVPGLKGDAGEKGDKGAPGRPGRVGPTGEKGDMGD------KG 74 P G P G+ PG G G G +G PG G +GP GEKG G G Sbjct: 528 PKGSLGPQGE---------PGPPGQQGTPGTQGLPGPQGAIGPHGEKGPQGKPGLPGMPG 578 Query: 75 QKGSVGRHGKIGPIGSKGEKGDSGDIGP---PGPNGEPGL 111 G G GK GP G+KG +G SG GP PGP G G+ Sbjct: 579 SDGPPGHPGKEGPPGTKGNQGPSGPQGPLGYPGPRGVKGV 618 Score = 64.7 bits (156), Expect = 8e-11 Identities = 45/125 (36%), Positives = 52/125 (41%), Gaps = 30/125 (24%) Query: 18 SLLPSGHPQPAGDDACSVQILVPGLKGDAGEKGDKGA------PGRPGRVGPTGEKGDMG 71 SL P G P P G +PG +G G G+KG PG PG GP G G G Sbjct: 531 SLGPQGEPGPPGQQGTPGTQGLPGPQGAIGPHGEKGPQGKPGLPGMPGSDGPPGHPGKEG 590 Query: 72 DKGQKGSVGRHGKIGPI------------------GSKGEKGD------SGDIGPPGPNG 107 G KG+ G G GP+ G KGEKG+ GDIG G G Sbjct: 591 PPGTKGNQGPSGPQGPLGYPGPRGVKGVDGIRGLKGHKGEKGEDGFPGFKGDIGVKGDRG 650 Query: 108 EPGLP 112 E G+P Sbjct: 651 EVGVP 655 Score = 64.7 bits (156), Expect = 8e-11 Identities = 38/90 (42%), Positives = 42/90 (46%), Gaps = 9/90 (10%) Query: 21 PSGHPQPAGDDACSVQILVPGLKGDAGEKGDKGAPGRPGRVGPTGEKGDMGDKGQKGSVG 80 P GHP G PG KG+ G G +G G PG G G G G KG KG G Sbjct: 582 PPGHPGKEGP---------PGTKGNQGPSGPQGPLGYPGPRGVKGVDGIRGLKGHKGEKG 632 Query: 81 RHGKIGPIGSKGEKGDSGDIGPPGPNGEPG 110 G G G G KGD G++G PG GE G Sbjct: 633 EDGFPGFKGDIGVKGDRGEVGVPGSRGEDG 662 Score = 64.7 bits (156), Expect = 8e-11 Identities = 38/93 (40%), Positives = 45/93 (48%), Gaps = 9/93 (9%) Query: 21 PSGHPQPAGDDACSVQILVPGLKGDAGE---KGDKGAPGRPGRVGPTGEKGDMGDKGQKG 77 P G P AG D PG +G G KGD+G G G GP G +G G G+KG Sbjct: 1008 PVGQPGAAGADG------EPGARGPQGHFGAKGDEGTRGFNGPPGPIGLQGLPGPSGEKG 1061 Query: 78 SVGRHGKIGPIGSKGEKGDSGDIGPPGPNGEPG 110 G G +GP G G +G +G G GP G PG Sbjct: 1062 ETGDVGPMGPPGPPGPRGPAGPNGADGPQGPPG 1094 Score = 64.3 bits (155), Expect = 1e-10 Identities = 35/76 (46%), Positives = 39/76 (51%), Gaps = 3/76 (3%) Query: 40 PGLKGDAGEKGDKGAPGR---PGRVGPTGEKGDMGDKGQKGSVGRHGKIGPIGSKGEKGD 96 PG KG G+ G KG PG PG GP GE G G G KG G G+ G GS G G+ Sbjct: 1144 PGPKGPTGDDGPKGNPGPVGFPGDPGPPGEGGPRGQDGAKGDRGEDGEPGQPGSPGPTGE 1203 Query: 97 SGDIGPPGPNGEPGLP 112 +G GP G G G P Sbjct: 1204 NGPPGPLGKRGPAGSP 1219 Score = 63.9 bits (154), Expect = 1e-10 Identities = 35/79 (44%), Positives = 40/79 (50%), Gaps = 9/79 (11%) Query: 41 GLKGDAGEKGDKGAPGRPGRVGPTGEKGDM---------GDKGQKGSVGRHGKIGPIGSK 91 G G AG +G GA G G G G KGD G+KG +G G G GP G Sbjct: 422 GPPGKAGRRGRAGADGARGMPGDPGVKGDRGFDGLPGLPGEKGHRGDTGAQGLPGPPGED 481 Query: 92 GEKGDSGDIGPPGPNGEPG 110 GE+GD G+IGP G GE G Sbjct: 482 GERGDDGEIGPRGLPGESG 500 Score = 63.9 bits (154), Expect = 1e-10 Identities = 30/73 (41%), Positives = 38/73 (52%) Query: 40 PGLKGDAGEKGDKGAPGRPGRVGPTGEKGDMGDKGQKGSVGRHGKIGPIGSKGEKGDSGD 99 PG G +GEKG +G G+ G G G G G +G +G+ G+ G G G G G G+ Sbjct: 709 PGFPGASGEKGARGLSGKSGPRGERGPTGPRGQRGPRGATGKSGAKGTSGGDGPHGPPGE 768 Query: 100 IGPPGPNGEPGLP 112 G PGP G G P Sbjct: 769 RGLPGPQGPNGFP 781 Score = 63.2 bits (152), Expect = 2e-10 Identities = 31/70 (44%), Positives = 38/70 (54%) Query: 41 GLKGDAGEKGDKGAPGRPGRVGPTGEKGDMGDKGQKGSVGRHGKIGPIGSKGEKGDSGDI 100 GL G +G +G++G G G+ GP G G G KG G G HG G G G +G +G Sbjct: 722 GLSGKSGPRGERGPTGPRGQRGPRGATGKSGAKGTSGGDGPHGPPGERGLPGPQGPNGFP 781 Query: 101 GPPGPNGEPG 110 GP GP G PG Sbjct: 782 GPKGPPGPPG 791 Score = 63.2 bits (152), Expect = 2e-10 Identities = 36/97 (37%), Positives = 46/97 (47%), Gaps = 9/97 (9%) Query: 23 GHPQPAGDDACSVQILVPGLKGDAGEKGDKGAPGRPGRVGPTGEKGDMGDKGQKGSVGRH 82 G P P+G+ + + G G G +G G G G GP G G++G G+KG G Sbjct: 1052 GLPGPSGEKGETGDVGPMGPPGPPGPRGPAGPNGADGPQGPPGGVGNLGPPGEKGEPGES 1111 Query: 83 GK---------IGPIGSKGEKGDSGDIGPPGPNGEPG 110 G GP G +GEKG+SG G PGP G G Sbjct: 1112 GSPGIQGEPGVKGPRGERGEKGESGQPGEPGPPGPKG 1148 Score = 62.4 bits (150), Expect = 4e-10 Identities = 37/92 (40%), Positives = 45/92 (48%), Gaps = 3/92 (3%) Query: 21 PSGHPQPAGDDACSVQILVPGLKGDAGEKGDKGAPGRPGRVGPTGEKGDMGDKGQKGSVG 80 PSG GD PG +G AG G G G PG VG G G+ G+ G+ GS G Sbjct: 1056 PSGEKGETGDVGPMGPPGPPGPRGPAGPNGADGPQGPPGGVGNLGPPGEKGEPGESGSPG 1115 Query: 81 RHGKIGPIGSKGEKGDSGDIGPPGPNGEPGLP 112 G+ G KG +G+ G+ G G GEPG P Sbjct: 1116 IQGEPGV---KGPRGERGEKGESGQPGEPGPP 1144 Score = 62.0 bits (149), Expect = 5e-10 Identities = 37/90 (41%), Positives = 40/90 (44%), Gaps = 6/90 (6%) Query: 21 PSGHPQPAGDDACSVQILVPGLKGDAGEKGDKGAPGRPGRVGPTGEKGDMGDKGQKGSVG 80 P G P G S G KG +G G G PG G GP G G G KG G G Sbjct: 738 PRGQRGPRGATGKS------GAKGTSGGDGPHGPPGERGLPGPQGPNGFPGPKGPPGPPG 791 Query: 81 RHGKIGPIGSKGEKGDSGDIGPPGPNGEPG 110 + G G G +GE G G GPPGP G G Sbjct: 792 KDGLPGHPGQRGEVGFQGKTGPPGPPGVVG 821 Score = 61.2 bits (147), Expect = 9e-10 Identities = 42/110 (38%), Positives = 47/110 (42%), Gaps = 30/110 (27%) Query: 22 SGHPQPAGDDACSVQILVPGLKGDAGEKGDKGAPGRPGRVGPTGEK------GDMGDKGQ 75 +G P P G V G +G AGE G G G PG GP GE+ G G KG Sbjct: 811 TGPPGPPG---------VVGPQGAAGETGPMGERGHPGPPGPPGEQGLPGTAGKEGTKGD 861 Query: 76 KGSVGRHGKIGPIGSK---------------GEKGDSGDIGPPGPNGEPG 110 G G GK GP G + G KG+ G GPPGP G PG Sbjct: 862 PGPPGAPGKDGPAGLRGFPGERGLPGTAGGPGLKGNEGPSGPPGPAGSPG 911 Score = 60.8 bits (146), Expect = 1e-09 Identities = 31/74 (41%), Positives = 38/74 (51%) Query: 41 GLKGDAGEKGDKGAPGRPGRVGPTGEKGDMGDKGQKGSVGRHGKIGPIGSKGEKGDSGDI 100 G G G+ G G G G +GP G +G G G G GR G+ G G++G GD G Sbjct: 389 GRPGPLGQPGSPGLKGESGDLGPQGPRGPQGLTGPPGKAGRRGRAGADGARGMPGDPGVK 448 Query: 101 GPPGPNGEPGLPCE 114 G G +G PGLP E Sbjct: 449 GDRGFDGLPGLPGE 462 Score = 57.8 bits (138), Expect = 1e-08 Identities = 35/84 (41%), Positives = 43/84 (51%), Gaps = 9/84 (10%) Query: 36 QILVPGLKGDAGEKGDKGAPGRPGRVGP---TGEKGDMGDKGQKGSVGRHGKIGPI---- 88 ++ VPG +G+ G +G KG G G GP GEKG +G G G GR G G + Sbjct: 651 EVGVPGSRGEDGPEGPKGRTGPTGDPGPPGLMGEKGKLGVPGLPGYPGRQGPKGSLGFPG 710 Query: 89 --GSKGEKGDSGDIGPPGPNGEPG 110 G+ GEKG G G GP GE G Sbjct: 711 FPGASGEKGARGLSGKSGPRGERG 734 Score = 56.2 bits (134), Expect = 3e-08 Identities = 29/70 (41%), Positives = 37/70 (52%) Query: 42 LKGDAGEKGDKGAPGRPGRVGPTGEKGDMGDKGQKGSVGRHGKIGPIGSKGEKGDSGDIG 101 L+G G G G PG G+ G G KG+ GD G +G G G GP G G +G +G G Sbjct: 378 LRGPPGPMGYTGRPGPLGQPGSPGLKGESGDLGPQGPRGPQGLTGPPGKAGRRGRAGADG 437 Query: 102 PPGPNGEPGL 111 G G+PG+ Sbjct: 438 ARGMPGDPGV 447 Score = 51.6 bits (122), Expect = 7e-07 Identities = 30/71 (42%), Positives = 35/71 (49%), Gaps = 3/71 (4%) Query: 44 GDAGEKGDKGAPG--RPGRVGPTGEKGDMGDKGQKGSVGRHGKIGPIGSKGEKGDSGDIG 101 G G KG+KG P PG + G G G G G G G GP+G GE+G G G Sbjct: 270 GPRGLKGEKGEPAVLEPGML-VEGPPGPEGPAGLIGPPGIQGNPGPVGDPGERGPPGRAG 328 Query: 102 PPGPNGEPGLP 112 PG +G PG P Sbjct: 329 LPGSDGAPGPP 339 Score = 49.7 bits (117), Expect = 3e-06 Identities = 42/149 (28%), Positives = 53/149 (35%), Gaps = 49/149 (32%) Query: 19 LLPSGHPQPAGDDACSVQILVPGLKGDAGEKGDKGAPGRPGRVGPTGEKGDMGD------ 72 +L G P P G I PG++G+ G GD G G PGR G G G G Sbjct: 288 MLVEGPPGPEGPAGL---IGPPGIQGNPGPVGDPGERGPPGRAGLPGSDGAPGPPGTSLM 344 Query: 73 ----------------------------------KGQKGSVGRHGKIGPIGS------KG 92 +G G +G G+ GP+G KG Sbjct: 345 LPFRFGSGGGDKGPVVAAQEAQAQAILQQARLALRGPPGPMGYTGRPGPLGQPGSPGLKG 404 Query: 93 EKGDSGDIGPPGPNGEPGLPCECSQLRKA 121 E GD G GP GP G G P + + +A Sbjct: 405 ESGDLGPQGPRGPQGLTGPPGKAGRRGRA 433 Score = 32.3 bits (72), Expect = 0.45 Identities = 17/41 (41%), Positives = 19/41 (46%) Query: 21 PSGHPQPAGDDACSVQILVPGLKGDAGEKGDKGAPGRPGRV 61 P G P PAG G KG+ G +G G PG PG V Sbjct: 1353 PPGLPGPAGPKGAKGATGPGGPKGEKGVQGPPGHPGPPGEV 1393 >gi|111118970 collagen, type XI, alpha 2 isoform 1 preproprotein [Homo sapiens] Length = 1736 Score = 83.6 bits (205), Expect = 2e-16 Identities = 45/111 (40%), Positives = 59/111 (53%), Gaps = 21/111 (18%) Query: 21 PSGHPQPAGDDACSVQILVPGLKGDAGEKGDKGAPGRPGRVGPTGE-------------- 66 P+G P AG+D ++ PG KG G KG+ G PG PG +GP G+ Sbjct: 1073 PAGPPGVAGEDGDKGEVGDPGQKGTKGNKGEHGPPGPPGPIGPVGQPGAAGADGEPGARG 1132 Query: 67 -KGDMGDKGQKGSVGRHGKIGPI------GSKGEKGDSGDIGPPGPNGEPG 110 +G G KG +G+ G +G GPI G GEKG++GD+GP GP G PG Sbjct: 1133 PQGHFGAKGDEGTRGFNGPPGPIGLQGLPGPSGEKGETGDVGPMGPPGPPG 1183 Score = 80.5 bits (197), Expect = 1e-15 Identities = 43/91 (47%), Positives = 52/91 (57%), Gaps = 12/91 (13%) Query: 22 SGHPQPAGDDACSVQILVPGLKGDAGEKGDKGAPGRPGRVGPTGEKGDMGDKGQKGSVGR 81 +G P P G +PGL+GDAG KG+KG PG G +GP GE+G+ GD+G G G Sbjct: 1386 AGPPGPVGPPG------LPGLRGDAGAKGEKGHPGLIGLIGPPGEQGEKGDRGLPGPQGS 1439 Query: 82 HGKIGPIGSKGEKGDSGDIGPPGPNGEPGLP 112 G+ KGE G G GP GP G PGLP Sbjct: 1440 PGQ------KGEMGIPGASGPIGPGGPPGLP 1464 Score = 78.6 bits (192), Expect = 5e-15 Identities = 39/90 (43%), Positives = 47/90 (52%) Query: 21 PSGHPQPAGDDACSVQILVPGLKGDAGEKGDKGAPGRPGRVGPTGEKGDMGDKGQKGSVG 80 P+G P G + PG KG+ GE G G G PG GP GE+G+ G+ GQ G G Sbjct: 1190 PNGADGPQGPPGGVGNLGPPGEKGEPGESGSPGIQGEPGVKGPRGERGEKGESGQPGEPG 1249 Query: 81 RHGKIGPIGSKGEKGDSGDIGPPGPNGEPG 110 G GP G G KG+ G +G PG G PG Sbjct: 1250 PPGPKGPTGDDGPKGNPGPVGFPGDPGPPG 1279 Score = 78.2 bits (191), Expect = 7e-15 Identities = 40/90 (44%), Positives = 47/90 (52%) Query: 23 GHPQPAGDDACSVQILVPGLKGDAGEKGDKGAPGRPGRVGPTGEKGDMGDKGQKGSVGRH 82 G P +G + V G +G+ GEKG+ G PG PG GP G GD G KG G VG Sbjct: 1213 GEPGESGSPGIQGEPGVKGPRGERGEKGESGQPGEPGPPGPKGPTGDDGPKGNPGPVGFP 1272 Query: 83 GKIGPIGSKGEKGDSGDIGPPGPNGEPGLP 112 G GP G G +G G G G +GEPG P Sbjct: 1273 GDPGPPGEGGPRGQDGAKGDRGEDGEPGQP 1302 Score = 76.3 bits (186), Expect = 3e-14 Identities = 42/90 (46%), Positives = 46/90 (51%), Gaps = 6/90 (6%) Query: 21 PSGHPQPAGDDACSVQILVPGLKGDAGEKGDKGAPGRPGRVGPTGEKGDMGDKGQKGSVG 80 P+G P P G +PG G G G G G PG VGP G G GD G KG G Sbjct: 1358 PAGKPGPDGLRG------LPGSVGQQGRPGATGQAGPPGPVGPPGLPGLRGDAGAKGEKG 1411 Query: 81 RHGKIGPIGSKGEKGDSGDIGPPGPNGEPG 110 G IG IG GE+G+ GD G PGP G PG Sbjct: 1412 HPGLIGLIGPPGEQGEKGDRGLPGPQGSPG 1441 Score = 75.9 bits (185), Expect = 4e-14 Identities = 42/97 (43%), Positives = 51/97 (52%), Gaps = 12/97 (12%) Query: 23 GHPQPAGDDACSVQILVPGLKGDAGEKGDKGAPGRPGRVGPTGEKGDMGDKGQ------- 75 GHP P G + +PG G G KGD G PG PG+ GP G +G G++G Sbjct: 943 GHPGPPGPPG---EQGLPGTAGKEGTKGDPGPPGAPGKDGPAGLRGFPGERGLPGTAGGP 999 Query: 76 --KGSVGRHGKIGPIGSKGEKGDSGDIGPPGPNGEPG 110 KG+ G G GP GS GE+G +G GP GP G PG Sbjct: 1000 GLKGNEGPSGPPGPAGSPGERGAAGSGGPIGPPGRPG 1036 Score = 75.1 bits (183), Expect = 6e-14 Identities = 40/90 (44%), Positives = 46/90 (51%) Query: 21 PSGHPQPAGDDACSVQILVPGLKGDAGEKGDKGAPGRPGRVGPTGEKGDMGDKGQKGSVG 80 P G P P G + + VPG KG G G G G G GP G G G+ G KG VG Sbjct: 1031 PPGRPGPQGPPGAAGEKGVPGEKGPIGPTGRDGVQGPVGLPGPAGPPGVAGEDGDKGEVG 1090 Query: 81 RHGKIGPIGSKGEKGDSGDIGPPGPNGEPG 110 G+ G G+KGE G G GP GP G+PG Sbjct: 1091 DPGQKGTKGNKGEHGPPGPPGPIGPVGQPG 1120 Score = 75.1 bits (183), Expect = 6e-14 Identities = 42/95 (44%), Positives = 50/95 (52%), Gaps = 3/95 (3%) Query: 21 PSGHPQPAGDDACSVQILVPGLKGDAGEKGDKGAPGR---PGRVGPTGEKGDMGDKGQKG 77 P G PAG + PG G+ G G+KG PG PG G G KG G++G+KG Sbjct: 1181 PPGPRGPAGPNGADGPQGPPGGVGNLGPPGEKGEPGESGSPGIQGEPGVKGPRGERGEKG 1240 Query: 78 SVGRHGKIGPIGSKGEKGDSGDIGPPGPNGEPGLP 112 G+ G+ GP G KG GD G G PGP G PG P Sbjct: 1241 ESGQPGEPGPPGPKGPTGDDGPKGNPGPVGFPGDP 1275 Score = 74.7 bits (182), Expect = 8e-14 Identities = 44/101 (43%), Positives = 51/101 (50%), Gaps = 9/101 (8%) Query: 21 PSGHPQPAGDDACSVQILVPGLKGDAGEKGDKGAPGRPGRVGPTGEKGDMGDKGQKGSVG 80 P+G P P G ++ VPGL G G +G KG+ G PG G +GEKG G G+ G G Sbjct: 779 PTGDPGPPGLMGEKGKLGVPGLPGYPGRQGPKGSLGFPGFPGASGEKGARGLSGKSGPRG 838 Query: 81 RHGKIGP---------IGSKGEKGDSGDIGPPGPNGEPGLP 112 G GP G G KG SG GP GP GE GLP Sbjct: 839 ERGPTGPRGQRGPRGATGKSGAKGTSGGDGPHGPPGERGLP 879 Score = 74.3 bits (181), Expect = 1e-13 Identities = 45/102 (44%), Positives = 50/102 (49%), Gaps = 21/102 (20%) Query: 21 PSGHPQPAGDDACSVQILVPGLKGDAGEKGDKGAPGRPGRVGP---TGEKGDMGDKGQKG 77 PSG P PAG PG +G AG G G PGRPG GP GEKG G+KG G Sbjct: 1007 PSGPPGPAGS---------PGERGAAGSGGPIGPPGRPGPQGPPGAAGEKGVPGEKGPIG 1057 Query: 78 SVGRHGKIGPI---------GSKGEKGDSGDIGPPGPNGEPG 110 GR G GP+ G GE GD G++G PG G G Sbjct: 1058 PTGRDGVQGPVGLPGPAGPPGVAGEDGDKGEVGDPGQKGTKG 1099 Score = 73.9 bits (180), Expect = 1e-13 Identities = 40/93 (43%), Positives = 48/93 (51%), Gaps = 3/93 (3%) Query: 21 PSGHPQPAG---DDACSVQILVPGLKGDAGEKGDKGAPGRPGRVGPTGEKGDMGDKGQKG 77 P G+P P G D + G G G++G+ G PG+PG GPTGE G G G++G Sbjct: 1262 PKGNPGPVGFPGDPGPPGEGGPRGQDGAKGDRGEDGEPGQPGSPGPTGENGPPGPLGKRG 1321 Query: 78 SVGRHGKIGPIGSKGEKGDSGDIGPPGPNGEPG 110 G G G G KG KGD G IG PG G G Sbjct: 1322 PAGSPGSEGRQGGKGAKGDPGAIGAPGKTGPVG 1354 Score = 73.6 bits (179), Expect = 2e-13 Identities = 40/93 (43%), Positives = 50/93 (53%), Gaps = 6/93 (6%) Query: 21 PSGHPQPAGDDACSVQILVPGLKGDAGEKGDKGAPGRPGRVGP---TGEKGDMGDKGQKG 77 P G P P G D PG +G+ G +G G PG PG VGP GE G MG++G G Sbjct: 890 PKGPPGPPGKDGLPGH---PGQRGEVGFQGKTGPPGPPGVVGPQGAAGETGPMGERGHPG 946 Query: 78 SVGRHGKIGPIGSKGEKGDSGDIGPPGPNGEPG 110 G G+ G G+ G++G GD GPPG G+ G Sbjct: 947 PPGPPGEQGLPGTAGKEGTKGDPGPPGAPGKDG 979 Score = 72.0 bits (175), Expect = 5e-13 Identities = 40/92 (43%), Positives = 45/92 (48%), Gaps = 9/92 (9%) Query: 21 PSGHPQPAGDDACSVQILVPGLKGDAGEKGDKGAPGRPGRVGPTGEKGDMGDKGQKGSVG 80 P G PAG PG +G G KG KG PG G G TG G G G+ G G Sbjct: 1316 PLGKRGPAGS---------PGSEGRQGGKGAKGDPGAIGAPGKTGPVGPAGPAGKPGPDG 1366 Query: 81 RHGKIGPIGSKGEKGDSGDIGPPGPNGEPGLP 112 G G +G +G G +G GPPGP G PGLP Sbjct: 1367 LRGLPGSVGQQGRPGATGQAGPPGPVGPPGLP 1398 Score = 71.2 bits (173), Expect = 9e-13 Identities = 40/91 (43%), Positives = 46/91 (50%) Query: 22 SGHPQPAGDDACSVQILVPGLKGDAGEKGDKGAPGRPGRVGPTGEKGDMGDKGQKGSVGR 81 +G AG D PG+KGD G G G PG G G TG +G G G+ G G Sbjct: 534 AGRRGRAGADGARGMPGDPGVKGDRGFDGLPGLPGEKGHRGDTGAQGLPGPPGEDGERGD 593 Query: 82 HGKIGPIGSKGEKGDSGDIGPPGPNGEPGLP 112 G+IGP G GE G G +GP GP G PG P Sbjct: 594 DGEIGPRGLPGESGPRGLLGPKGPPGIPGPP 624 Score = 70.5 bits (171), Expect = 1e-12 Identities = 39/97 (40%), Positives = 49/97 (50%), Gaps = 6/97 (6%) Query: 21 PSGHPQPAGDDACSV------QILVPGLKGDAGEKGDKGAPGRPGRVGPTGEKGDMGDKG 74 P GH GD+ I + GL G +GEKG+ G G G GP G +G G G Sbjct: 1133 PQGHFGAKGDEGTRGFNGPPGPIGLQGLPGPSGEKGETGDVGPMGPPGPPGPRGPAGPNG 1192 Query: 75 QKGSVGRHGKIGPIGSKGEKGDSGDIGPPGPNGEPGL 111 G G G +G +G GEKG+ G+ G PG GEPG+ Sbjct: 1193 ADGPQGPPGGVGNLGPPGEKGEPGESGSPGIQGEPGV 1229 Score = 69.7 bits (169), Expect = 3e-12 Identities = 41/98 (41%), Positives = 52/98 (53%), Gaps = 15/98 (15%) Query: 21 PSGHPQPAGDDACSVQILVPGLKGDAGEKGDKGAPGRPGRVGPTGEKGDMGDKGQKGSVG 80 P G+P P G + GLKG GEKG+ G PG G +G G++G++G G + Sbjct: 713 PLGYPGPRGVKGVDG---IRGLKGHKGEKGEDGFPGFKGDIGVKGDRGEVGVPGSR---- 765 Query: 81 RHGKIGPIGSKGEKGDSGDIGPPGPNGE------PGLP 112 G+ GP G KG G +GD GPPG GE PGLP Sbjct: 766 --GEDGPEGPKGRTGPTGDPGPPGLMGEKGKLGVPGLP 801 Score = 68.9 bits (167), Expect = 4e-12 Identities = 38/89 (42%), Positives = 46/89 (51%) Query: 23 GHPQPAGDDACSVQILVPGLKGDAGEKGDKGAPGRPGRVGPTGEKGDMGDKGQKGSVGRH 82 G PAG + +PG G G KG++G G PG G GE+G G G G GR Sbjct: 976 GKDGPAGLRGFPGERGLPGTAGGPGLKGNEGPSGPPGPAGSPGERGAAGSGGPIGPPGRP 1035 Query: 83 GKIGPIGSKGEKGDSGDIGPPGPNGEPGL 111 G GP G+ GEKG G+ GP GP G G+ Sbjct: 1036 GPQGPPGAAGEKGVPGEKGPIGPTGRDGV 1064 Score = 68.2 bits (165), Expect = 7e-12 Identities = 36/80 (45%), Positives = 48/80 (60%), Gaps = 6/80 (7%) Query: 39 VPGLKGDAGEKGDKGAPGRPGR---VGPTGEKGDMGDKGQKGSVGRHGKIGPIGSKGE-- 93 +PG +G G G KG PG PG+ G G++G++G +G+ G G G +GP G+ GE Sbjct: 878 LPGPQGPNGFPGPKGPPGPPGKDGLPGHPGQRGEVGFQGKTGPPGPPGVVGPQGAAGETG 937 Query: 94 -KGDSGDIGPPGPNGEPGLP 112 G+ G GPPGP GE GLP Sbjct: 938 PMGERGHPGPPGPPGEQGLP 957 Score = 67.8 bits (164), Expect = 1e-11 Identities = 39/89 (43%), Positives = 45/89 (50%), Gaps = 18/89 (20%) Query: 39 VPGLKGDAGEKGDKGAPGRPGRVGPTGEKGDMGDKGQKGSVGRHGKIGPIGSKGEKGDSG 98 +PGL G+ G +GD GA G PG P GE G+ GD G+ G G G+ GP G G KG G Sbjct: 563 LPGLPGEKGHRGDTGAQGLPG---PPGEDGERGDDGEIGPRGLPGESGPRGLLGPKGPPG 619 Query: 99 DIGPP---------------GPNGEPGLP 112 GPP GP GEPG P Sbjct: 620 IPGPPGVRGMDGPQGPKGSLGPQGEPGPP 648 Score = 67.8 bits (164), Expect = 1e-11 Identities = 41/101 (40%), Positives = 51/101 (50%), Gaps = 12/101 (11%) Query: 21 PSGHPQPAGDDACSVQILVPGLKGDAGEKGDKGAPGRPGRVGPTGEKGDMGDKGQKGSVG 80 P G GDD +I GL G++G +G G G PG GP G +G G +G KGS+G Sbjct: 584 PPGEDGERGDDG---EIGPRGLPGESGPRGLLGPKGPPGIPGPPGVRGMDGPQGPKGSLG 640 Query: 81 RHGKIGPIGSKGEKGDSGDIGP---------PGPNGEPGLP 112 G+ GP G +G G G GP GP G+PGLP Sbjct: 641 PQGEPGPPGQQGTPGTQGLPGPQGAIGPHGEKGPQGKPGLP 681 Score = 67.8 bits (164), Expect = 1e-11 Identities = 36/84 (42%), Positives = 43/84 (51%), Gaps = 9/84 (10%) Query: 40 PGLKGD---------AGEKGDKGAPGRPGRVGPTGEKGDMGDKGQKGSVGRHGKIGPIGS 90 PGLKG+ AG G++GA G G +GP G G G G G G G+ GPIG Sbjct: 999 PGLKGNEGPSGPPGPAGSPGERGAAGSGGPIGPPGRPGPQGPPGAAGEKGVPGEKGPIGP 1058 Query: 91 KGEKGDSGDIGPPGPNGEPGLPCE 114 G G G +G PGP G PG+ E Sbjct: 1059 TGRDGVQGPVGLPGPAGPPGVAGE 1082 Score = 67.8 bits (164), Expect = 1e-11 Identities = 38/90 (42%), Positives = 44/90 (48%), Gaps = 12/90 (13%) Query: 21 PSGHPQPAGDDACSVQILVPGLKGDAGEKGDKGAPGRPGRVGPTGEKGDMGDKGQKGSVG 80 P G P GDD G KG+ G G G PG PG GP G+ G GD+G+ G G Sbjct: 1250 PPGPKGPTGDD---------GPKGNPGPVGFPGDPGPPGEGGPRGQDGAKGDRGEDGEPG 1300 Query: 81 RHGKIGPIGSKGEKGDSGDIGPPGPNGEPG 110 + G GP GE G G +G GP G PG Sbjct: 1301 QPGSPGP---TGENGPPGPLGKRGPAGSPG 1327 Score = 67.4 bits (163), Expect = 1e-11 Identities = 37/88 (42%), Positives = 41/88 (46%), Gaps = 6/88 (6%) Query: 23 GHPQPAGDDACSVQILVPGLKGDAGEKGDKGAPGRPGRVGPTGEKGDMGDKGQKGSVGRH 82 G P P G + PG KG G G G PG PG+ G G +G G G G VG Sbjct: 877 GLPGPQGPNG------FPGPKGPPGPPGKDGLPGHPGQRGEVGFQGKTGPPGPPGVVGPQ 930 Query: 83 GKIGPIGSKGEKGDSGDIGPPGPNGEPG 110 G G G GE+G G GPPG G PG Sbjct: 931 GAAGETGPMGERGHPGPPGPPGEQGLPG 958 Score = 67.4 bits (163), Expect = 1e-11 Identities = 37/90 (41%), Positives = 43/90 (47%) Query: 22 SGHPQPAGDDACSVQILVPGLKGDAGEKGDKGAPGRPGRVGPTGEKGDMGDKGQKGSVGR 81 +G P P G + G +G G KGD GA G PG+ GP G G G G G G Sbjct: 1311 NGPPGPLGKRGPAGSPGSEGRQGGKGAKGDPGAIGAPGKTGPVGPAGPAGKPGPDGLRGL 1370 Query: 82 HGKIGPIGSKGEKGDSGDIGPPGPNGEPGL 111 G +G G G G +G GP GP G PGL Sbjct: 1371 PGSVGQQGRPGATGQAGPPGPVGPPGLPGL 1400 Score = 67.0 bits (162), Expect = 2e-11 Identities = 42/110 (38%), Positives = 51/110 (46%), Gaps = 9/110 (8%) Query: 23 GHPQ------PAGDDACSVQILVPGLKGDAGEKGDKGAPGRPGRVGPTGEKGDMGDKGQK 76 GHP P G+ +PG +G G+KG+ G PG G +GP G G G G K Sbjct: 1411 GHPGLIGLIGPPGEQGEKGDRGLPGPQGSPGQKGEMGIPGASGPIGPGGPPGLPGPAGPK 1470 Query: 77 GSVGRHGKIGPIGSKGEKGDSGDIGPPGPNGEPGLPCECSQLRKAIGEMD 126 G+ G GP G KGEKG G G PGP GE P +K +D Sbjct: 1471 GA---KGATGPGGPKGEKGVQGPPGHPGPPGEVIQPLPIQMPKKTRRSVD 1517 Score = 66.2 bits (160), Expect = 3e-11 Identities = 41/100 (41%), Positives = 48/100 (48%), Gaps = 18/100 (18%) Query: 23 GHPQPAGDDACSVQILVPGLKGDAGEKGDKGAPGRP------------GRVGPTGEKGDM 70 GH G+D PG KGD G KGD+G G P GR GPTG+ G Sbjct: 733 GHKGEKGEDG------FPGFKGDIGVKGDRGEVGVPGSRGEDGPEGPKGRTGPTGDPGPP 786 Query: 71 GDKGQKGSVGRHGKIGPIGSKGEKGDSGDIGPPGPNGEPG 110 G G+KG +G G G G +G KG G G PG +GE G Sbjct: 787 GLMGEKGKLGVPGLPGYPGRQGPKGSLGFPGFPGASGEKG 826 Score = 65.5 bits (158), Expect = 5e-11 Identities = 37/92 (40%), Positives = 43/92 (46%), Gaps = 9/92 (9%) Query: 21 PSGHPQPAGDDACSVQILVPGLKGDAGEKGDKGAPGRPGRVGPTGEKGDMGDKGQKGSVG 80 P G P P G V G+ G G KG G G PG G G G G G +G++G Sbjct: 617 PPGIPGPPG---------VRGMDGPQGPKGSLGPQGEPGPPGQQGTPGTQGLPGPQGAIG 667 Query: 81 RHGKIGPIGSKGEKGDSGDIGPPGPNGEPGLP 112 HG+ GP G G G G GPPG G+ G P Sbjct: 668 PHGEKGPQGKPGLPGMPGSDGPPGHPGKEGPP 699 Score = 65.1 bits (157), Expect = 6e-11 Identities = 40/101 (39%), Positives = 48/101 (47%), Gaps = 18/101 (17%) Query: 22 SGHPQPAGDDACSVQILVPGLKGDAGEKGDKGA------------PGRPGRVGPTGEKGD 69 +G P P G PGLKG++G+ G +G GR GR G G +G Sbjct: 495 TGRPGPLGQPGS------PGLKGESGDLGPQGPRGPQGLTGPPGKAGRRGRAGADGARGM 548 Query: 70 MGDKGQKGSVGRHGKIGPIGSKGEKGDSGDIGPPGPNGEPG 110 GD G KG G G G G KG +GD+G G PGP GE G Sbjct: 549 PGDPGVKGDRGFDGLPGLPGEKGHRGDTGAQGLPGPPGEDG 589 Score = 64.7 bits (156), Expect = 8e-11 Identities = 40/100 (40%), Positives = 46/100 (46%), Gaps = 18/100 (18%) Query: 21 PSGHPQPAGDDACSVQILVPGLKGDAGEKGDKGAPGRPGRVGPTGEKGDMGD------KG 74 P G P G+ PG G G G +G PG G +GP GEKG G G Sbjct: 635 PKGSLGPQGE---------PGPPGQQGTPGTQGLPGPQGAIGPHGEKGPQGKPGLPGMPG 685 Query: 75 QKGSVGRHGKIGPIGSKGEKGDSGDIGP---PGPNGEPGL 111 G G GK GP G+KG +G SG GP PGP G G+ Sbjct: 686 SDGPPGHPGKEGPPGTKGNQGPSGPQGPLGYPGPRGVKGV 725 Score = 64.7 bits (156), Expect = 8e-11 Identities = 45/125 (36%), Positives = 52/125 (41%), Gaps = 30/125 (24%) Query: 18 SLLPSGHPQPAGDDACSVQILVPGLKGDAGEKGDKGA------PGRPGRVGPTGEKGDMG 71 SL P G P P G +PG +G G G+KG PG PG GP G G G Sbjct: 638 SLGPQGEPGPPGQQGTPGTQGLPGPQGAIGPHGEKGPQGKPGLPGMPGSDGPPGHPGKEG 697 Query: 72 DKGQKGSVGRHGKIGPI------------------GSKGEKGD------SGDIGPPGPNG 107 G KG+ G G GP+ G KGEKG+ GDIG G G Sbjct: 698 PPGTKGNQGPSGPQGPLGYPGPRGVKGVDGIRGLKGHKGEKGEDGFPGFKGDIGVKGDRG 757 Query: 108 EPGLP 112 E G+P Sbjct: 758 EVGVP 762 Score = 64.7 bits (156), Expect = 8e-11 Identities = 38/90 (42%), Positives = 42/90 (46%), Gaps = 9/90 (10%) Query: 21 PSGHPQPAGDDACSVQILVPGLKGDAGEKGDKGAPGRPGRVGPTGEKGDMGDKGQKGSVG 80 P GHP G PG KG+ G G +G G PG G G G G KG KG G Sbjct: 689 PPGHPGKEGP---------PGTKGNQGPSGPQGPLGYPGPRGVKGVDGIRGLKGHKGEKG 739 Query: 81 RHGKIGPIGSKGEKGDSGDIGPPGPNGEPG 110 G G G G KGD G++G PG GE G Sbjct: 740 EDGFPGFKGDIGVKGDRGEVGVPGSRGEDG 769 Score = 64.7 bits (156), Expect = 8e-11 Identities = 38/93 (40%), Positives = 45/93 (48%), Gaps = 9/93 (9%) Query: 21 PSGHPQPAGDDACSVQILVPGLKGDAGE---KGDKGAPGRPGRVGPTGEKGDMGDKGQKG 77 P G P AG D PG +G G KGD+G G G GP G +G G G+KG Sbjct: 1115 PVGQPGAAGADG------EPGARGPQGHFGAKGDEGTRGFNGPPGPIGLQGLPGPSGEKG 1168 Query: 78 SVGRHGKIGPIGSKGEKGDSGDIGPPGPNGEPG 110 G G +GP G G +G +G G GP G PG Sbjct: 1169 ETGDVGPMGPPGPPGPRGPAGPNGADGPQGPPG 1201 Score = 64.3 bits (155), Expect = 1e-10 Identities = 35/76 (46%), Positives = 39/76 (51%), Gaps = 3/76 (3%) Query: 40 PGLKGDAGEKGDKGAPGR---PGRVGPTGEKGDMGDKGQKGSVGRHGKIGPIGSKGEKGD 96 PG KG G+ G KG PG PG GP GE G G G KG G G+ G GS G G+ Sbjct: 1251 PGPKGPTGDDGPKGNPGPVGFPGDPGPPGEGGPRGQDGAKGDRGEDGEPGQPGSPGPTGE 1310 Query: 97 SGDIGPPGPNGEPGLP 112 +G GP G G G P Sbjct: 1311 NGPPGPLGKRGPAGSP 1326 Score = 63.9 bits (154), Expect = 1e-10 Identities = 35/79 (44%), Positives = 40/79 (50%), Gaps = 9/79 (11%) Query: 41 GLKGDAGEKGDKGAPGRPGRVGPTGEKGDM---------GDKGQKGSVGRHGKIGPIGSK 91 G G AG +G GA G G G G KGD G+KG +G G G GP G Sbjct: 529 GPPGKAGRRGRAGADGARGMPGDPGVKGDRGFDGLPGLPGEKGHRGDTGAQGLPGPPGED 588 Query: 92 GEKGDSGDIGPPGPNGEPG 110 GE+GD G+IGP G GE G Sbjct: 589 GERGDDGEIGPRGLPGESG 607 Score = 63.9 bits (154), Expect = 1e-10 Identities = 30/73 (41%), Positives = 38/73 (52%) Query: 40 PGLKGDAGEKGDKGAPGRPGRVGPTGEKGDMGDKGQKGSVGRHGKIGPIGSKGEKGDSGD 99 PG G +GEKG +G G+ G G G G G +G +G+ G+ G G G G G G+ Sbjct: 816 PGFPGASGEKGARGLSGKSGPRGERGPTGPRGQRGPRGATGKSGAKGTSGGDGPHGPPGE 875 Query: 100 IGPPGPNGEPGLP 112 G PGP G G P Sbjct: 876 RGLPGPQGPNGFP 888 Score = 63.2 bits (152), Expect = 2e-10 Identities = 31/70 (44%), Positives = 38/70 (54%) Query: 41 GLKGDAGEKGDKGAPGRPGRVGPTGEKGDMGDKGQKGSVGRHGKIGPIGSKGEKGDSGDI 100 GL G +G +G++G G G+ GP G G G KG G G HG G G G +G +G Sbjct: 829 GLSGKSGPRGERGPTGPRGQRGPRGATGKSGAKGTSGGDGPHGPPGERGLPGPQGPNGFP 888 Query: 101 GPPGPNGEPG 110 GP GP G PG Sbjct: 889 GPKGPPGPPG 898 Score = 63.2 bits (152), Expect = 2e-10 Identities = 36/97 (37%), Positives = 46/97 (47%), Gaps = 9/97 (9%) Query: 23 GHPQPAGDDACSVQILVPGLKGDAGEKGDKGAPGRPGRVGPTGEKGDMGDKGQKGSVGRH 82 G P P+G+ + + G G G +G G G G GP G G++G G+KG G Sbjct: 1159 GLPGPSGEKGETGDVGPMGPPGPPGPRGPAGPNGADGPQGPPGGVGNLGPPGEKGEPGES 1218 Query: 83 GK---------IGPIGSKGEKGDSGDIGPPGPNGEPG 110 G GP G +GEKG+SG G PGP G G Sbjct: 1219 GSPGIQGEPGVKGPRGERGEKGESGQPGEPGPPGPKG 1255 Score = 62.4 bits (150), Expect = 4e-10 Identities = 37/92 (40%), Positives = 45/92 (48%), Gaps = 3/92 (3%) Query: 21 PSGHPQPAGDDACSVQILVPGLKGDAGEKGDKGAPGRPGRVGPTGEKGDMGDKGQKGSVG 80 PSG GD PG +G AG G G G PG VG G G+ G+ G+ GS G Sbjct: 1163 PSGEKGETGDVGPMGPPGPPGPRGPAGPNGADGPQGPPGGVGNLGPPGEKGEPGESGSPG 1222 Query: 81 RHGKIGPIGSKGEKGDSGDIGPPGPNGEPGLP 112 G+ G KG +G+ G+ G G GEPG P Sbjct: 1223 IQGEPGV---KGPRGERGEKGESGQPGEPGPP 1251 Score = 62.0 bits (149), Expect = 5e-10 Identities = 37/90 (41%), Positives = 40/90 (44%), Gaps = 6/90 (6%) Query: 21 PSGHPQPAGDDACSVQILVPGLKGDAGEKGDKGAPGRPGRVGPTGEKGDMGDKGQKGSVG 80 P G P G S G KG +G G G PG G GP G G G KG G G Sbjct: 845 PRGQRGPRGATGKS------GAKGTSGGDGPHGPPGERGLPGPQGPNGFPGPKGPPGPPG 898 Query: 81 RHGKIGPIGSKGEKGDSGDIGPPGPNGEPG 110 + G G G +GE G G GPPGP G G Sbjct: 899 KDGLPGHPGQRGEVGFQGKTGPPGPPGVVG 928 Score = 61.2 bits (147), Expect = 9e-10 Identities = 42/110 (38%), Positives = 47/110 (42%), Gaps = 30/110 (27%) Query: 22 SGHPQPAGDDACSVQILVPGLKGDAGEKGDKGAPGRPGRVGPTGEK------GDMGDKGQ 75 +G P P G V G +G AGE G G G PG GP GE+ G G KG Sbjct: 918 TGPPGPPG---------VVGPQGAAGETGPMGERGHPGPPGPPGEQGLPGTAGKEGTKGD 968 Query: 76 KGSVGRHGKIGPIGSK---------------GEKGDSGDIGPPGPNGEPG 110 G G GK GP G + G KG+ G GPPGP G PG Sbjct: 969 PGPPGAPGKDGPAGLRGFPGERGLPGTAGGPGLKGNEGPSGPPGPAGSPG 1018 Score = 60.8 bits (146), Expect = 1e-09 Identities = 31/74 (41%), Positives = 38/74 (51%) Query: 41 GLKGDAGEKGDKGAPGRPGRVGPTGEKGDMGDKGQKGSVGRHGKIGPIGSKGEKGDSGDI 100 G G G+ G G G G +GP G +G G G G GR G+ G G++G GD G Sbjct: 496 GRPGPLGQPGSPGLKGESGDLGPQGPRGPQGLTGPPGKAGRRGRAGADGARGMPGDPGVK 555 Query: 101 GPPGPNGEPGLPCE 114 G G +G PGLP E Sbjct: 556 GDRGFDGLPGLPGE 569 Score = 57.8 bits (138), Expect = 1e-08 Identities = 35/84 (41%), Positives = 43/84 (51%), Gaps = 9/84 (10%) Query: 36 QILVPGLKGDAGEKGDKGAPGRPGRVGP---TGEKGDMGDKGQKGSVGRHGKIGPI---- 88 ++ VPG +G+ G +G KG G G GP GEKG +G G G GR G G + Sbjct: 758 EVGVPGSRGEDGPEGPKGRTGPTGDPGPPGLMGEKGKLGVPGLPGYPGRQGPKGSLGFPG 817 Query: 89 --GSKGEKGDSGDIGPPGPNGEPG 110 G+ GEKG G G GP GE G Sbjct: 818 FPGASGEKGARGLSGKSGPRGERG 841 Score = 56.2 bits (134), Expect = 3e-08 Identities = 29/70 (41%), Positives = 37/70 (52%) Query: 42 LKGDAGEKGDKGAPGRPGRVGPTGEKGDMGDKGQKGSVGRHGKIGPIGSKGEKGDSGDIG 101 L+G G G G PG G+ G G KG+ GD G +G G G GP G G +G +G G Sbjct: 485 LRGPPGPMGYTGRPGPLGQPGSPGLKGESGDLGPQGPRGPQGLTGPPGKAGRRGRAGADG 544 Query: 102 PPGPNGEPGL 111 G G+PG+ Sbjct: 545 ARGMPGDPGV 554 Score = 51.6 bits (122), Expect = 7e-07 Identities = 30/71 (42%), Positives = 35/71 (49%), Gaps = 3/71 (4%) Query: 44 GDAGEKGDKGAPG--RPGRVGPTGEKGDMGDKGQKGSVGRHGKIGPIGSKGEKGDSGDIG 101 G G KG+KG P PG + G G G G G G G GP+G GE+G G G Sbjct: 377 GPRGLKGEKGEPAVLEPGML-VEGPPGPEGPAGLIGPPGIQGNPGPVGDPGERGPPGRAG 435 Query: 102 PPGPNGEPGLP 112 PG +G PG P Sbjct: 436 LPGSDGAPGPP 446 Score = 49.7 bits (117), Expect = 3e-06 Identities = 42/149 (28%), Positives = 53/149 (35%), Gaps = 49/149 (32%) Query: 19 LLPSGHPQPAGDDACSVQILVPGLKGDAGEKGDKGAPGRPGRVGPTGEKGDMGD------ 72 +L G P P G I PG++G+ G GD G G PGR G G G G Sbjct: 395 MLVEGPPGPEGPAGL---IGPPGIQGNPGPVGDPGERGPPGRAGLPGSDGAPGPPGTSLM 451 Query: 73 ----------------------------------KGQKGSVGRHGKIGPIGS------KG 92 +G G +G G+ GP+G KG Sbjct: 452 LPFRFGSGGGDKGPVVAAQEAQAQAILQQARLALRGPPGPMGYTGRPGPLGQPGSPGLKG 511 Query: 93 EKGDSGDIGPPGPNGEPGLPCECSQLRKA 121 E GD G GP GP G G P + + +A Sbjct: 512 ESGDLGPQGPRGPQGLTGPPGKAGRRGRA 540 Score = 32.3 bits (72), Expect = 0.45 Identities = 17/41 (41%), Positives = 19/41 (46%) Query: 21 PSGHPQPAGDDACSVQILVPGLKGDAGEKGDKGAPGRPGRV 61 P G P PAG G KG+ G +G G PG PG V Sbjct: 1460 PPGLPGPAGPKGAKGATGPGGPKGEKGVQGPPGHPGPPGEV 1500 >gi|119829187 alpha 1 type XVII collagen [Homo sapiens] Length = 1497 Score = 81.3 bits (199), Expect = 8e-16 Identities = 44/93 (47%), Positives = 50/93 (53%), Gaps = 20/93 (21%) Query: 40 PGLKGDAGE---KGDKGAPGRPGRVGPTGEKGDMGDKGQKGSVGRHGKIGPIGSK----- 91 PG KGD G KGD+G PG PG GP G G G KGQKGSVG G GP+G + Sbjct: 569 PGPKGDMGSPGPKGDRGFPGTPGIPGPLGHPGPQGPKGQKGSVGDPGMEGPMGQRGREGP 628 Query: 92 ------------GEKGDSGDIGPPGPNGEPGLP 112 GEKG+ G G PGP+G PG+P Sbjct: 629 MGPRGEAGPPGSGEKGERGAAGEPGPHGPPGVP 661 Score = 77.8 bits (190), Expect = 9e-15 Identities = 44/119 (36%), Positives = 55/119 (46%), Gaps = 29/119 (24%) Query: 21 PSGHPQPAGDDACSVQILVPGLKGD--------------------AGEKGDKGAPGRPGR 60 P GHP P G + PG++G +GEKG++GA G PG Sbjct: 595 PLGHPGPQGPKGQKGSVGDPGMEGPMGQRGREGPMGPRGEAGPPGSGEKGERGAAGEPGP 654 Query: 61 VGPTGEKGDMGDKGQKGSVGRHGKIGPIGSK---------GEKGDSGDIGPPGPNGEPG 110 GP G G +G KG GS G G GP+G + G KGD G +GPPGP G+ G Sbjct: 655 HGPPGVPGSVGPKGSSGSPGPQGPPGPVGLQGLRGEVGLPGVKGDKGPMGPPGPKGDQG 713 Score = 76.3 bits (186), Expect = 3e-14 Identities = 42/104 (40%), Positives = 51/104 (49%), Gaps = 12/104 (11%) Query: 21 PSGHPQPAGDDACSVQILVPGLKGDAG------------EKGDKGAPGRPGRVGPTGEKG 68 P G P P G ++ +PG+KGD G EKG +G G PG G G G Sbjct: 675 PQGPPGPVGLQGLRGEVGLPGVKGDKGPMGPPGPKGDQGEKGPRGLTGEPGMRGLPGAVG 734 Query: 69 DMGDKGQKGSVGRHGKIGPIGSKGEKGDSGDIGPPGPNGEPGLP 112 + G KG G G G GP G +G G G GPPGP+G+PG P Sbjct: 735 EPGAKGAMGPAGPDGHQGPRGEQGLTGMPGIRGPPGPSGDPGKP 778 Score = 69.7 bits (169), Expect = 3e-12 Identities = 42/112 (37%), Positives = 50/112 (44%), Gaps = 5/112 (4%) Query: 1 MRGNLALVGVLISLAFLSLLPSGHPQPAGDDACSVQILVPGLKGDAGEKGDKGAPGRPGR 60 +RG + L GV P G P P GD + G G G G G PG G Sbjct: 687 LRGEVGLPGVKGDKG-----PMGPPGPKGDQGEKGPRGLTGEPGMRGLPGAVGEPGAKGA 741 Query: 61 VGPTGEKGDMGDKGQKGSVGRHGKIGPIGSKGEKGDSGDIGPPGPNGEPGLP 112 +GP G G G +G++G G G GP G G+ G G GP GP G PG P Sbjct: 742 MGPAGPDGHQGPRGEQGLTGMPGIRGPPGPSGDPGKPGLTGPQGPQGLPGTP 793 Score = 66.2 bits (160), Expect = 3e-11 Identities = 39/92 (42%), Positives = 46/92 (50%), Gaps = 12/92 (13%) Query: 22 SGHPQPAGDDACSVQILVPGLKGDAGEKGDKGAPGR---PGRVGPTGEKGDMGDKGQKGS 78 +G P P G PG+ G G KG G+PG PG VG G +G++G G KG Sbjct: 649 AGEPGPHGP---------PGVPGSVGPKGSSGSPGPQGPPGPVGLQGLRGEVGLPGVKGD 699 Query: 79 VGRHGKIGPIGSKGEKGDSGDIGPPGPNGEPG 110 G G GP G +GEKG G G PG G PG Sbjct: 700 KGPMGPPGPKGDQGEKGPRGLTGEPGMRGLPG 731 Score = 58.9 bits (141), Expect = 4e-09 Identities = 41/126 (32%), Positives = 48/126 (38%), Gaps = 39/126 (30%) Query: 21 PSGHPQPAGDDACSVQILVPGLKGDAGEKGDKGAPGRPGRVGPTGEKGDMGDKGQKGSVG 80 P GH P G+ + +PG++G G GD G PG G GP G G G G KG G Sbjct: 747 PDGHQGPRGEQGLTG---MPGIRGPPGPSGDPGKPGLTGPQGPQGLPGTPGRPGIKGEPG 803 Query: 81 RHGKI------------------------GPIGSKGEKGDSG------------DIGPPG 104 GKI GP G+ G G +G GPPG Sbjct: 804 APGKIVTSEGSSMLTVPGPPGPPGAMGPPGPPGAPGPAGPAGLPGHQEVLNLQGPPGPPG 863 Query: 105 PNGEPG 110 P G PG Sbjct: 864 PRGPPG 869 Score = 58.5 bits (140), Expect = 6e-09 Identities = 39/102 (38%), Positives = 43/102 (42%), Gaps = 18/102 (17%) Query: 21 PSGHPQPAGDDACSVQILVPGLKGDAGEKGDKG------------APGRPGRVGPTGEKG 68 P G P P GD PG +G GE+G G G PG GP G KG Sbjct: 910 PPGPPGPKGDQG------PPGPRGHQGEQGLPGFSTSGSSSFGLNLQGPPGPPGPQGPKG 963 Query: 69 DMGDKGQKGSVGRHGKIGPIGSKGEKGDSGDIGPPGPNGEPG 110 D GD G G++G GS SG GPPGP G PG Sbjct: 964 DKGDPGVPGALGIPSGPSEGGSSSTMYVSGPPGPPGPPGPPG 1005 Score = 57.8 bits (138), Expect = 1e-08 Identities = 41/102 (40%), Positives = 45/102 (44%), Gaps = 10/102 (9%) Query: 21 PSGHPQPAGDDACSVQILVPGLKGDAGEKGDKGAPGR--PGRVGPTGEKGD--MGDKGQK 76 P G P PAG V L+G G G +G PG PG GP G G+ G G Sbjct: 834 PPGAPGPAGPAGLPGHQEVLNLQGPPGPPGPRGPPGPSIPGPPGPRGPPGEGLPGPPGPP 893 Query: 77 GSVGRH------GKIGPIGSKGEKGDSGDIGPPGPNGEPGLP 112 GS + G GP G G KGD G GP G GE GLP Sbjct: 894 GSFLSNSETFLSGPPGPPGPPGPKGDQGPPGPRGHQGEQGLP 935 Score = 57.0 bits (136), Expect = 2e-08 Identities = 46/152 (30%), Positives = 61/152 (40%), Gaps = 31/152 (20%) Query: 23 GHPQPAGDDACSVQILV---PGLKGDAGEKGDKGAPGRPGRVG----------------- 62 G P P G + + + PG G G KGD+G PG G G Sbjct: 888 GPPGPPGSFLSNSETFLSGPPGPPGPPGPKGDQGPPGPRGHQGEQGLPGFSTSGSSSFGL 947 Query: 63 ----PTGEKGDMGDKGQKGSVGRHGKIGPIGSKGEKGDSGDI---GPPGPNGEPGLPCEC 115 P G G G KG KG G G +G E G S + GPPGP G PG P Sbjct: 948 NLQGPPGPPGPQGPKGDKGDPGVPGALGIPSGPSEGGSSSTMYVSGPPGPPGPPGPPGSI 1007 Query: 116 SQLRKAIGEMDNQVSQLTSELKFIKNAVAGVR 147 S + I + ++ Q S I++ ++GV+ Sbjct: 1008 SSSGQEIQQYISEYMQSDS----IRSYLSGVQ 1035 Score = 55.5 bits (132), Expect = 5e-08 Identities = 28/59 (47%), Positives = 33/59 (55%) Query: 52 KGAPGRPGRVGPTGEKGDMGDKGQKGSVGRHGKIGPIGSKGEKGDSGDIGPPGPNGEPG 110 +G+PG G +G G KGD G G G G G GP G KG+KG GD G GP G+ G Sbjct: 566 RGSPGPKGDMGSPGPKGDRGFPGTPGIPGPLGHPGPQGPKGQKGSVGDPGMEGPMGQRG 624 Score = 52.8 bits (125), Expect = 3e-07 Identities = 37/105 (35%), Positives = 43/105 (40%), Gaps = 15/105 (14%) Query: 23 GHPQPAGDDACSVQILVPGLKGDAGEKGDKGAPGRPGRVGPTGEKGDMGD---KGQKGSV 79 G P G+ + G G G +G++G G PG GP G GD G G +G Sbjct: 728 GLPGAVGEPGAKGAMGPAGPDGHQGPRGEQGLTGMPGIRGPPGPSGDPGKPGLTGPQGPQ 787 Query: 80 GRHGKIGPIGSKGEKGDSGDI------------GPPGPNGEPGLP 112 G G G G KGE G G I GPPGP G G P Sbjct: 788 GLPGTPGRPGIKGEPGAPGKIVTSEGSSMLTVPGPPGPPGAMGPP 832 Score = 52.4 bits (124), Expect = 4e-07 Identities = 43/127 (33%), Positives = 48/127 (37%), Gaps = 35/127 (27%) Query: 21 PSGHPQPAGDDACSVQILVPGLKGDAGEKGDKGAPGRPGRV------------GPTGEKG 68 P G P P G S+ PG +G GE G G PG PG GP G G Sbjct: 858 PPGPPGPRGPPGPSIPG-PPGPRGPPGE-GLPGPPGPPGSFLSNSETFLSGPPGPPGPPG 915 Query: 69 DMGDKGQKGSVGRHGK---------------------IGPIGSKGEKGDSGDIGPPGPNG 107 GD+G G G G+ GP G +G KGD GD G PG G Sbjct: 916 PKGDQGPPGPRGHQGEQGLPGFSTSGSSSFGLNLQGPPGPPGPQGPKGDKGDPGVPGALG 975 Query: 108 EPGLPCE 114 P P E Sbjct: 976 IPSGPSE 982 Score = 50.8 bits (120), Expect = 1e-06 Identities = 34/94 (36%), Positives = 42/94 (44%), Gaps = 3/94 (3%) Query: 9 GVLISLAFLSLLPSGHPQPAGDDACS-VQILVPGLKGDAGE--KGDKGAPGRPGRVGPTG 65 G+L +A+ P G P P G S V + D + + G PG+ G G Sbjct: 1388 GLLQGMAYTVQGPPGQPGPQGPPGISKVFSAYSNVTADLMDFFQTYGAIQGPPGQKGEMG 1447 Query: 66 EKGDMGDKGQKGSVGRHGKIGPIGSKGEKGDSGD 99 G GD+G G G G GP G KGEKGD GD Sbjct: 1448 TPGPKGDRGPAGPPGHPGPPGPRGHKGEKGDKGD 1481 Score = 46.6 bits (109), Expect = 2e-05 Identities = 20/41 (48%), Positives = 24/41 (58%) Query: 41 GLKGDAGEKGDKGAPGRPGRVGPTGEKGDMGDKGQKGSVGR 81 G G G++G G PG PG GP G KG+ GDKG + GR Sbjct: 1447 GTPGPKGDRGPAGPPGHPGPPGPRGHKGEKGDKGDQVYAGR 1487 Score = 43.9 bits (102), Expect = 1e-04 Identities = 27/77 (35%), Positives = 32/77 (41%), Gaps = 18/77 (23%) Query: 52 KGAPGRPGRVGPTGEK----------GDMGD--------KGQKGSVGRHGKIGPIGSKGE 93 +G PG+PG GP G D+ D +G G G G GP G +G Sbjct: 1398 QGPPGQPGPQGPPGISKVFSAYSNVTADLMDFFQTYGAIQGPPGQKGEMGTPGPKGDRGP 1457 Query: 94 KGDSGDIGPPGPNGEPG 110 G G GPPGP G G Sbjct: 1458 AGPPGHPGPPGPRGHKG 1474 Score = 43.5 bits (101), Expect = 2e-04 Identities = 21/38 (55%), Positives = 22/38 (57%) Query: 40 PGLKGDAGEKGDKGAPGRPGRVGPTGEKGDMGDKGQKG 77 PG KGD G G G PG PG G GEKGD GD+ G Sbjct: 1449 PGPKGDRGPAGPPGHPGPPGPRGHKGEKGDKGDQVYAG 1486 Score = 42.0 bits (97), Expect = 6e-04 Identities = 34/106 (32%), Positives = 37/106 (34%), Gaps = 28/106 (26%) Query: 21 PSGHPQPAGDDACSVQILVPGLKGDAGEKGDKGAPGRPGRVGPTGEKGDMGDKGQKGSVG 80 P G P P G KGD G+ G GA G P G M G G G Sbjct: 952 PPGPPGPQGP------------KGDKGDPGVPGALGIPSGPSEGGSSSTMYVSGPPGPPG 999 Query: 81 RHGKIGPIGSKGEKGD----------------SGDIGPPGPNGEPG 110 G G I S G++ SG GPPGP G PG Sbjct: 1000 PPGPPGSISSSGQEIQQYISEYMQSDSIRSYLSGVQGPPGPPGPPG 1045 Score = 36.6 bits (83), Expect = 0.024 Identities = 29/100 (29%), Positives = 43/100 (43%), Gaps = 6/100 (6%) Query: 12 ISLAFLSLLPSGHPQPAGDDACSVQILVPGLKGDAGEKGDKGAPGRPGRVGPTGEKGDMG 71 +S + +S+ G P P G S + L+ L+G +G G PG GP G G++ Sbjct: 1138 MSSSGISIGLPGPPGPPGLPGTSYEELLSLLRGSEF----RGIVGPPGPPGPPGIPGNVW 1193 Query: 72 DKGQKGSVGRHGKIGPIGSKGEKGDSGDIGPPGPNGEPGL 111 + + + G G G GPPGP G PG+ Sbjct: 1194 SSISVEDLSSY--LHTAGLSFIPGPPGPPGPPGPRGPPGV 1231 Score = 33.5 bits (75), Expect = 0.20 Identities = 25/84 (29%), Positives = 34/84 (40%), Gaps = 21/84 (25%) Query: 50 GDKGAPGRPGRVGPTG----EKGDMGDK-----GQKG-SVGRHGKIGPIGSKGEKGDS-- 97 G +G PG PG G + ++ + G S+G G GP G G + Sbjct: 1106 GPRGPPGPPGASGDGSLLSLDYAELSSRILSYMSSSGISIGLPGPPGPPGLPGTSYEELL 1165 Query: 98 ---------GDIGPPGPNGEPGLP 112 G +GPPGP G PG+P Sbjct: 1166 SLLRGSEFRGIVGPPGPPGPPGIP 1189 Score = 28.1 bits (61), Expect = 8.5 Identities = 16/40 (40%), Positives = 19/40 (47%), Gaps = 9/40 (22%) Query: 21 PSGHPQPAGDDACSVQILVPGLKGDAGEKGDKGAPGRPGR 60 P GHP P G G KG+ G+KGD+ GR R Sbjct: 1460 PPGHPGPPGPR---------GHKGEKGDKGDQVYAGRRRR 1490 >gi|98986321 gliomedin [Homo sapiens] Length = 551 Score = 80.9 bits (198), Expect = 1e-15 Identities = 45/108 (41%), Positives = 54/108 (50%), Gaps = 16/108 (14%) Query: 21 PSGHPQPAGDDACSVQILVPGLKGDAGEKGDKGAPGRPGRVG---PTGEKGDMGDKGQKG 77 PSG P P G + G G G KG+KGA G+ G++G G G+ G+KG G Sbjct: 140 PSGPPGPPGAGGLPGHNGLDGQPGPQGPKGEKGANGKRGKMGIPGAAGNPGERGEKGDHG 199 Query: 78 SVGRHGKIGPIGSKGEKGDSGDI-------------GPPGPNGEPGLP 112 +G G GP G KGEKGD GD+ GPPGP G PG P Sbjct: 200 ELGLQGNEGPPGQKGEKGDKGDVSNDVLLAGAKGDQGPPGPPGPPGPP 247 Score = 50.4 bits (119), Expect = 2e-06 Identities = 43/137 (31%), Positives = 61/137 (44%), Gaps = 10/137 (7%) Query: 22 SGHPQPAGDDACSVQILVPGLKGDAGEKGDKGAPGRPGR-VGPTGEKGDMGDKGQKGSVG 80 +G+P G+ ++ + G +G G+KG+KG G V G KGD G G G G Sbjct: 186 AGNPGERGEKGDHGELGLQGNEGPPGQKGEKGDKGDVSNDVLLAGAKGDQGPPGPPGPPG 245 Query: 81 RHGKIGPIGSKGEKGDSGDIGPPGPNGE-PGLPCECSQLRKAIGEMDNQVS-----QLTS 134 G GP GS+ KG P NG+ PG C +G+ D + S Q S Sbjct: 246 PPGPPGPPGSRRAKGPR---QPSMFNGQCPGETCAIPNDDTLVGKADEKASEHHSPQAES 302 Query: 135 ELKFIKNAVAGVRETES 151 + I N V ++ TE+ Sbjct: 303 MITSIGNPVQVLKVTET 319 Score = 43.1 bits (100), Expect = 3e-04 Identities = 24/52 (46%), Positives = 28/52 (53%), Gaps = 3/52 (5%) Query: 62 GPTGEKGDMGDKGQKGSVGRHGKIGPIGSKGEKGDS---GDIGPPGPNGEPG 110 GP+G G G G G G G+ GP G KGEKG + G +G PG G PG Sbjct: 139 GPSGPPGPPGAGGLPGHNGLDGQPGPQGPKGEKGANGKRGKMGIPGAAGNPG 190 Score = 38.9 bits (89), Expect = 0.005 Identities = 21/54 (38%), Positives = 25/54 (46%), Gaps = 1/54 (1%) Query: 21 PSGHPQPAGDDA-CSVQILVPGLKGDAGEKGDKGAPGRPGRVGPTGEKGDMGDK 73 P G GD S +L+ G KGD G G G PG PG GP G + G + Sbjct: 209 PPGQKGEKGDKGDVSNDVLLAGAKGDQGPPGPPGPPGPPGPPGPPGSRRAKGPR 262 >gi|18780273 collagen, type XXI, alpha 1 precursor [Homo sapiens] Length = 957 Score = 80.1 bits (196), Expect = 2e-15 Identities = 42/75 (56%), Positives = 51/75 (68%), Gaps = 6/75 (8%) Query: 39 VPGLKGDAG---EKGDKGAPGRPGRVGPTGEKGDMGDKGQKGSVGRHGKIGPIGSKGEKG 95 +PG KG+ G +KGD+G PG PG G G KG+MG KG KGS G +GK G+KGEKG Sbjct: 501 LPGYKGEPGRDGDKGDRGLPGFPGLHGMPGSKGEMGAKGDKGSPGFYGK---KGAKGEKG 557 Query: 96 DSGDIGPPGPNGEPG 110 ++G G PGP GEPG Sbjct: 558 NAGFPGLPGPAGEPG 572 Score = 77.8 bits (190), Expect = 9e-15 Identities = 41/80 (51%), Positives = 51/80 (63%), Gaps = 6/80 (7%) Query: 39 VPGLKGDAGEKGDKGAPGRPGRVGPTGEKGDMGD---KGQKGSVGRHGKIGPIGSKGEKG 95 +PG KG+ G KGDKG+PG G+ G GEKG+ G G G GRHGK G +GS G KG Sbjct: 528 MPGSKGEMGAKGDKGSPGFYGKKGAKGEKGNAGFPGLPGPAGEPGRHGKDGLMGSPGFKG 587 Query: 96 DSGDIGPPGPN---GEPGLP 112 ++G G PG + GEPG+P Sbjct: 588 EAGSPGAPGQDGTRGEPGIP 607 Score = 73.9 bits (180), Expect = 1e-13 Identities = 40/92 (43%), Positives = 50/92 (54%), Gaps = 9/92 (9%) Query: 21 PSGHPQPAGDDACSVQILVPGLKGDAGEKGDKGAPGRPGRVGPTGEKGDMGDKGQKGSVG 80 P+G P G D GL G G KG+ G+PG PG+ G GE G G G +G +G Sbjct: 567 PAGEPGRHGKD---------GLMGSPGFKGEAGSPGAPGQDGTRGEPGIPGFPGNRGLMG 617 Query: 81 RHGKIGPIGSKGEKGDSGDIGPPGPNGEPGLP 112 + G+IGP G +G+KG G G G NG PG P Sbjct: 618 QKGEIGPPGQQGKKGAPGMPGLMGSNGSPGQP 649 Score = 70.9 bits (172), Expect = 1e-12 Identities = 40/99 (40%), Positives = 51/99 (51%), Gaps = 9/99 (9%) Query: 23 GHPQPAGDDACSVQILVPGLKGDAGEKGD---------KGAPGRPGRVGPTGEKGDMGDK 73 G P G + +PG++G G+KG+ KG GR G G G +G G K Sbjct: 674 GEPGATGSPGEPGYMGLPGIQGKKGDKGNQGEKGIQGQKGENGRQGIPGQQGIQGHHGAK 733 Query: 74 GQKGSVGRHGKIGPIGSKGEKGDSGDIGPPGPNGEPGLP 112 G++G G G G IGSKGE G G +GP GP G+PG P Sbjct: 734 GERGEKGEPGVRGAIGSKGESGVDGLMGPAGPKGQPGDP 772 Score = 70.5 bits (171), Expect = 1e-12 Identities = 35/79 (44%), Positives = 46/79 (58%), Gaps = 9/79 (11%) Query: 41 GLKGDAGEKGDKGAPGRPGRVGPTGEKGDMGDKGQ---------KGSVGRHGKIGPIGSK 91 G++G GE G +G PG+ G G G KG+ G+KG+ KG G G +GP G K Sbjct: 707 GIQGQKGENGRQGIPGQQGIQGHHGAKGERGEKGEPGVRGAIGSKGESGVDGLMGPAGPK 766 Query: 92 GEKGDSGDIGPPGPNGEPG 110 G+ GD G GPPG +G+PG Sbjct: 767 GQPGDPGPQGPPGLDGKPG 785 Score = 67.4 bits (163), Expect = 1e-11 Identities = 39/103 (37%), Positives = 48/103 (46%), Gaps = 12/103 (11%) Query: 22 SGHPQPAGDDACSVQILVPGLKGDAG------------EKGDKGAPGRPGRVGPTGEKGD 69 +G P G D + +PG G+ G ++G KGAPG PG +G G G Sbjct: 589 AGSPGAPGQDGTRGEPGIPGFPGNRGLMGQKGEIGPPGQQGKKGAPGMPGLMGSNGSPGQ 648 Query: 70 MGDKGQKGSVGRHGKIGPIGSKGEKGDSGDIGPPGPNGEPGLP 112 G G KGS G G G G+ G KG+ G G PG G GLP Sbjct: 649 PGTPGSKGSKGEPGIQGMPGASGLKGEPGATGSPGEPGYMGLP 691 Score = 63.2 bits (152), Expect = 2e-10 Identities = 40/99 (40%), Positives = 49/99 (49%), Gaps = 9/99 (9%) Query: 23 GHP-QPAGDDACSVQILV--PGLKGDAGEKGDKGAPGRPGRVGPTGEKGDMGDKGQKGSV 79 G+P QP D Q + PG+ G G +G +G PG G G G+KGD G G G Sbjct: 467 GYPGQPGQDGKPGYQGIAGTPGVPGSPGIQGARGLPGYKGEPGRDGDKGDRGLPGFPGLH 526 Query: 80 GRHGKIGPIGSKGEKGDSGDIGPPGPNGE------PGLP 112 G G G +G+KG+KG G G G GE PGLP Sbjct: 527 GMPGSKGEMGAKGDKGSPGFYGKKGAKGEKGNAGFPGLP 565 Score = 62.4 bits (150), Expect = 4e-10 Identities = 31/73 (42%), Positives = 37/73 (50%) Query: 40 PGLKGDAGEKGDKGAPGRPGRVGPTGEKGDMGDKGQKGSVGRHGKIGPIGSKGEKGDSGD 99 PG G G KG+ G G PG G GE G G G+ G +G G G G KG +G+ G Sbjct: 649 PGTPGSKGSKGEPGIQGMPGASGLKGEPGATGSPGEPGYMGLPGIQGKKGDKGNQGEKGI 708 Query: 100 IGPPGPNGEPGLP 112 G G NG G+P Sbjct: 709 QGQKGENGRQGIP 721 Score = 62.4 bits (150), Expect = 4e-10 Identities = 34/78 (43%), Positives = 42/78 (53%), Gaps = 2/78 (2%) Query: 39 VPGLKGDAGEKGDKGAPGRPGRVGPTGEKGDMGDKGQKGSVGRHGKIGPIGSK--GEKGD 96 +PG G G +G +G PG PGR G G G G G +G G G+ G GS+ G G+ Sbjct: 829 IPGPPGPIGPEGPRGLPGLPGRDGVPGLVGVPGRPGVRGLKGLPGRNGEKGSQGFGYPGE 888 Query: 97 SGDIGPPGPNGEPGLPCE 114 G GPPGP G PG+ E Sbjct: 889 QGPPGPPGPEGPPGISKE 906 Score = 62.0 bits (149), Expect = 5e-10 Identities = 36/88 (40%), Positives = 41/88 (46%) Query: 23 GHPQPAGDDACSVQILVPGLKGDAGEKGDKGAPGRPGRVGPTGEKGDMGDKGQKGSVGRH 82 G P G + Q PG KG GE G +G PG G G G G G+ G G G Sbjct: 635 GMPGLMGSNGSPGQPGTPGSKGSKGEPGIQGMPGASGLKGEPGATGSPGEPGYMGLPGIQ 694 Query: 83 GKIGPIGSKGEKGDSGDIGPPGPNGEPG 110 GK G G++GEKG G G G G PG Sbjct: 695 GKKGDKGNQGEKGIQGQKGENGRQGIPG 722 Score = 60.1 bits (144), Expect = 2e-09 Identities = 32/71 (45%), Positives = 36/71 (50%) Query: 41 GLKGDAGEKGDKGAPGRPGRVGPTGEKGDMGDKGQKGSVGRHGKIGPIGSKGEKGDSGDI 100 G G G+KG G PG G G G+ G G KG KG G G G G KGE G +G Sbjct: 623 GPPGQQGKKGAPGMPGLMGSNGSPGQPGTPGSKGSKGEPGIQGMPGASGLKGEPGATGSP 682 Query: 101 GPPGPNGEPGL 111 G PG G PG+ Sbjct: 683 GEPGYMGLPGI 693 Score = 59.7 bits (143), Expect = 3e-09 Identities = 34/71 (47%), Positives = 38/71 (53%) Query: 41 GLKGDAGEKGDKGAPGRPGRVGPTGEKGDMGDKGQKGSVGRHGKIGPIGSKGEKGDSGDI 100 G KGD G G+ G PG+PG+ G G +G G G GS G G G G KGE G GD Sbjct: 455 GPKGDPGLPGNPGYPGQPGQDGKPGYQGIAGTPGVPGSPGIQGARGLPGYKGEPGRDGDK 514 Query: 101 GPPGPNGEPGL 111 G G G PGL Sbjct: 515 GDRGLPGFPGL 525 Score = 59.3 bits (142), Expect = 3e-09 Identities = 41/102 (40%), Positives = 46/102 (45%), Gaps = 13/102 (12%) Query: 21 PSGHPQPAGDDACSVQILVPGLKGDAGEKGDKGAPGRPGRVGPTGEKGD--MGDKGQKGS 78 P G P G D VPGL G G G +G G PGR G G +G G++G G Sbjct: 841 PRGLPGLPGRDG------VPGLVGVPGRPGVRGLKGLPGRNGEKGSQGFGYPGEQGPPGP 894 Query: 79 VGRHG-----KIGPIGSKGEKGDSGDIGPPGPNGEPGLPCEC 115 G G K GP G G G GD G PG G+PG P C Sbjct: 895 PGPEGPPGISKEGPPGDPGLPGKDGDHGKPGIQGQPGPPGIC 936 Score = 58.2 bits (139), Expect = 8e-09 Identities = 32/76 (42%), Positives = 39/76 (51%) Query: 37 ILVPGLKGDAGEKGDKGAPGRPGRVGPTGEKGDMGDKGQKGSVGRHGKIGPIGSKGEKGD 96 I PG G G KGD G PG PG G G+ G G +G G+ G G G G++G G Sbjct: 445 ICPPGKPGLQGPKGDPGLPGNPGYPGQPGQDGKPGYQGIAGTPGVPGSPGIQGARGLPGY 504 Query: 97 SGDIGPPGPNGEPGLP 112 G+ G G G+ GLP Sbjct: 505 KGEPGRDGDKGDRGLP 520 Score = 55.5 bits (132), Expect = 5e-08 Identities = 34/107 (31%), Positives = 42/107 (39%), Gaps = 34/107 (31%) Query: 40 PGLKGDAGEKGDKGAPGRPGRVGPTGEKGDMGDKGQKGSVGRHGK--------------- 84 PG++G G KG+ G G G GP G+ GD G +G G G+ G+ Sbjct: 742 PGVRGAIGSKGESGVDGLMGPAGPKGQPGDPGPQGPPGLDGKPGREFSEQFIRQVCTDVI 801 Query: 85 -------------------IGPIGSKGEKGDSGDIGPPGPNGEPGLP 112 + GS G G G IGP GP G PGLP Sbjct: 802 RAQLPVLLQSGRIRNCDHCLSQHGSPGIPGPPGPIGPEGPRGLPGLP 848 Score = 55.1 bits (131), Expect = 6e-08 Identities = 29/70 (41%), Positives = 36/70 (51%) Query: 41 GLKGDAGEKGDKGAPGRPGRVGPTGEKGDMGDKGQKGSVGRHGKIGPIGSKGEKGDSGDI 100 G G G G G+PG+PG G G KG+ G +G G+ G G+ G GS GE G G Sbjct: 632 GAPGMPGLMGSNGSPGQPGTPGSKGSKGEPGIQGMPGASGLKGEPGATGSPGEPGYMGLP 691 Query: 101 GPPGPNGEPG 110 G G G+ G Sbjct: 692 GIQGKKGDKG 701 Score = 55.1 bits (131), Expect = 6e-08 Identities = 31/80 (38%), Positives = 38/80 (47%), Gaps = 9/80 (11%) Query: 40 PGLKGDAGEKGDKGAPGRPGRVGPTGEKGDM---------GDKGQKGSVGRHGKIGPIGS 90 PG+ G G G G PG PG G GE G G+ G GS G G +G G Sbjct: 634 PGMPGLMGSNGSPGQPGTPGSKGSKGEPGIQGMPGASGLKGEPGATGSPGEPGYMGLPGI 693 Query: 91 KGEKGDSGDIGPPGPNGEPG 110 +G+KGD G+ G G G+ G Sbjct: 694 QGKKGDKGNQGEKGIQGQKG 713 Score = 33.1 bits (74), Expect = 0.26 Identities = 20/53 (37%), Positives = 24/53 (45%), Gaps = 5/53 (9%) Query: 40 PGLKGDAGEKGDKGAPG-----RPGRVGPTGEKGDMGDKGQKGSVGRHGKIGP 87 PG +G G G +G PG PG G G+ GD G G +G G G P Sbjct: 886 PGEQGPPGPPGPEGPPGISKEGPPGDPGLPGKDGDHGKPGIQGQPGPPGICDP 938 Score = 30.8 bits (68), Expect = 1.3 Identities = 18/49 (36%), Positives = 23/49 (46%), Gaps = 5/49 (10%) Query: 21 PSGHPQPAGDDACSVQIL-----VPGLKGDAGEKGDKGAPGRPGRVGPT 64 P G P P G S + +PG GD G+ G +G PG PG P+ Sbjct: 891 PPGPPGPEGPPGISKEGPPGDPGLPGKDGDHGKPGIQGQPGPPGICDPS 939 >gi|73486666 alpha 1 type IX collagen isoform 1 precursor [Homo sapiens] Length = 921 Score = 80.1 bits (196), Expect = 2e-15 Identities = 44/101 (43%), Positives = 59/101 (58%), Gaps = 13/101 (12%) Query: 23 GHPQPAGDDACSVQIL-----VPGLKGDAGEKGDKGAPGRPGRVGPTGE------KGDMG 71 G P P GD +Q L +PG KG AGEKG GAPG+PG++G +G+ G++G Sbjct: 559 GKPGPPGD--AGLQGLPGVPGIPGAKGVAGEKGSTGAPGKPGQMGNSGKPGQQGPPGEVG 616 Query: 72 DKGQKGSVGRHGKIGPIGSKGEKGDSGDIGPPGPNGEPGLP 112 +G +G G G++GP+GS G G G +G PG G PG P Sbjct: 617 PRGPQGLPGSRGELGPVGSPGLPGKLGSLGSPGLPGLPGPP 657 Score = 73.6 bits (179), Expect = 2e-13 Identities = 36/82 (43%), Positives = 49/82 (59%), Gaps = 3/82 (3%) Query: 39 VPGLKGDAGEKGDKGAPGRPGRVGPTGEKGDMGD---KGQKGSVGRHGKIGPIGSKGEKG 95 +PG++G G KG+ G PGR G G G++G++G+ +G G+ G G G +G KGEKG Sbjct: 425 LPGMRGHKGAKGEIGEPGRQGHKGEEGDQGELGEVGAQGPPGAQGLRGITGIVGDKGEKG 484 Query: 96 DSGDIGPPGPNGEPGLPCECSQ 117 G G PGP G PG P + Q Sbjct: 485 ARGLDGEPGPQGLPGAPGDQGQ 506 Score = 73.2 bits (178), Expect = 2e-13 Identities = 37/75 (49%), Positives = 40/75 (53%) Query: 40 PGLKGDAGEKGDKGAPGRPGRVGPTGEKGDMGDKGQKGSVGRHGKIGPIGSKGEKGDSGD 99 PGL G G G G PG PG G G KGD G G+ G G G G G GE+G+ GD Sbjct: 636 PGLPGKLGSLGSPGLPGLPGPPGLPGMKGDRGVVGEPGPKGEQGASGEEGEAGERGELGD 695 Query: 100 IGPPGPNGEPGLPCE 114 IG PGP G G P E Sbjct: 696 IGLPGPKGSAGNPGE 710 Score = 70.1 bits (170), Expect = 2e-12 Identities = 46/115 (40%), Positives = 55/115 (47%), Gaps = 29/115 (25%) Query: 21 PSGHPQPAGDDACSVQILVPGLKGDAGEKGDKGAPGRPGRVGPTGEKGDMGDKGQKGSVG 80 P G P P G VPG+ G G++G KG PG P GP GE G G G+ G+ G Sbjct: 276 PPGPPGPPG---------VPGIDGIDGDRGPKGPPGPP---GPAGEPGKPGAPGKPGTPG 323 Query: 81 RHGKIGP------IGSKGEKGD-----------SGDIGPPGPNGEPGLPCECSQL 118 G GP IGSKG+KG+ G GPPGP G GLP E ++ Sbjct: 324 ADGLTGPDGSPGSIGSKGQKGEPGVPGSRGFPGRGIPGPPGPPGTAGLPGELGRV 378 Score = 69.7 bits (169), Expect = 3e-12 Identities = 49/117 (41%), Positives = 57/117 (48%), Gaps = 20/117 (17%) Query: 3 GNLALVGVLISLAFLSLLPSGHPQPAGDDACSVQILVPGLKGD------AGEKGDKGAPG 56 G+ L G L SL L G P P G +PG+KGD G KG++GA G Sbjct: 634 GSPGLPGKLGSLGSPGL--PGLPGPPG---------LPGMKGDRGVVGEPGPKGEQGASG 682 Query: 57 RPGRVGPTGEKGDMGDKGQKGSVGRHGK---IGPIGSKGEKGDSGDIGPPGPNGEPG 110 G G GE GD+G G KGS G G+ GP GS+G G G GPPGP G G Sbjct: 683 EEGEAGERGELGDIGLPGPKGSAGNPGEPGLRGPEGSRGLPGVEGPRGPPGPRGVQG 739 Score = 68.9 bits (167), Expect = 4e-12 Identities = 35/70 (50%), Positives = 41/70 (58%) Query: 41 GLKGDAGEKGDKGAPGRPGRVGPTGEKGDMGDKGQKGSVGRHGKIGPIGSKGEKGDSGDI 100 G +GD GE G+ GA G PG G G G +GDKG+KG+ G G+ GP G G GD G Sbjct: 448 GEEGDQGELGEVGAQGPPGAQGLRGITGIVGDKGEKGARGLDGEPGPQGLPGAPGDQGQR 507 Query: 101 GPPGPNGEPG 110 GPPG G G Sbjct: 508 GPPGEAGPKG 517 Score = 68.6 bits (166), Expect = 6e-12 Identities = 33/75 (44%), Positives = 45/75 (60%), Gaps = 3/75 (4%) Query: 39 VPGLKGDAGEKG---DKGAPGRPGRVGPTGEKGDMGDKGQKGSVGRHGKIGPIGSKGEKG 95 +PG KG+ G+ G D G G PG G G KG G+KG G+ G+ G++G G G++G Sbjct: 551 MPGTKGEPGKPGPPGDAGLQGLPGVPGIPGAKGVAGEKGSTGAPGKPGQMGNSGKPGQQG 610 Query: 96 DSGDIGPPGPNGEPG 110 G++GP GP G PG Sbjct: 611 PPGEVGPRGPQGLPG 625 Score = 67.0 bits (162), Expect = 2e-11 Identities = 34/72 (47%), Positives = 43/72 (59%), Gaps = 3/72 (4%) Query: 41 GLKGDAGEKGDKGAPGRPGRVGPTGEKGDMGDKGQKGSVGRHGKIGPIGSKGEKGDSGDI 100 G+ G G+KG+KGA G G GP G G GD+GQ+G G+ GP G +G +G G Sbjct: 472 GITGIVGDKGEKGARGLDGEPGPQGLPGAPGDQGQRGP---PGEAGPKGDRGAEGARGIP 528 Query: 101 GPPGPNGEPGLP 112 G PGP G+ GLP Sbjct: 529 GLPGPKGDTGLP 540 Score = 67.0 bits (162), Expect = 2e-11 Identities = 37/92 (40%), Positives = 45/92 (48%) Query: 21 PSGHPQPAGDDACSVQILVPGLKGDAGEKGDKGAPGRPGRVGPTGEKGDMGDKGQKGSVG 80 P G P G+ +PG G G G G PG PG G G++G +G+ G KG G Sbjct: 620 PQGLPGSRGELGPVGSPGLPGKLGSLGSPGLPGLPGPPGLPGMKGDRGVVGEPGPKGEQG 679 Query: 81 RHGKIGPIGSKGEKGDSGDIGPPGPNGEPGLP 112 G+ G G +GE GD G GP G G PG P Sbjct: 680 ASGEEGEAGERGELGDIGLPGPKGSAGNPGEP 711 Score = 67.0 bits (162), Expect = 2e-11 Identities = 45/115 (39%), Positives = 55/115 (47%), Gaps = 23/115 (20%) Query: 21 PSGHPQPAGDDACSVQILVPGL---------------KGDAGEKGDKGAPGRPGRVGPTG 65 P G P P G++ Q+ + GL KGD GEKG++G PGR GP G Sbjct: 797 PPGPPGPPGENGFPGQMGIRGLPGIKGPPGALGLRGPKGDLGEKGERGPPGR----GPNG 852 Query: 66 EKGDMGDKGQKG--SVGRHGKIGPIGSKGEKGDSGDIGPPGPNGEPGL--PCECS 116 G +G G G S GR+G+ G G G G G GPPGP G PG P C+ Sbjct: 853 LPGAIGLPGDPGPASYGRNGRDGERGPPGVAGIPGVPGPPGPPGLPGFCEPASCT 907 Score = 66.6 bits (161), Expect = 2e-11 Identities = 43/122 (35%), Positives = 49/122 (40%), Gaps = 32/122 (26%) Query: 21 PSGHPQPAGDDACSVQILVPGLKGDAGEKGDKGAPGRPGR------VGPTGEKGDMGDKG 74 P G P G D PG G AGE G GAPG+PG GP G G +G KG Sbjct: 282 PPGVPGIDGIDGDRGPKGPPGPPGPAGEPGKPGAPGKPGTPGADGLTGPDGSPGSIGSKG 341 Query: 75 QKGSVG--------------------------RHGKIGPIGSKGEKGDSGDIGPPGPNGE 108 QKG G G++GP+G G +G G GPPGP G Sbjct: 342 QKGEPGVPGSRGFPGRGIPGPPGPPGTAGLPGELGRVGPVGDPGRRGPPGPPGPPGPRGT 401 Query: 109 PG 110 G Sbjct: 402 IG 403 Score = 66.2 bits (160), Expect = 3e-11 Identities = 36/88 (40%), Positives = 44/88 (50%), Gaps = 3/88 (3%) Query: 23 GHPQPAGDDACSVQILVPGLKGDAGEKGDKGAPGRPGRVGPTGEKGDMGDKGQKGSVGRH 82 G P P G+ S + G G+ GE GD G PG G G GE G G +G +G G Sbjct: 670 GEPGPKGEQGASGE---EGEAGERGELGDIGLPGPKGSAGNPGEPGLRGPEGSRGLPGVE 726 Query: 83 GKIGPIGSKGEKGDSGDIGPPGPNGEPG 110 G GP G +G +G+ G G PG G PG Sbjct: 727 GPRGPPGPRGVQGEQGATGLPGVQGPPG 754 Score = 65.5 bits (158), Expect = 5e-11 Identities = 32/73 (43%), Positives = 41/73 (56%) Query: 39 VPGLKGDAGEKGDKGAPGRPGRVGPTGEKGDMGDKGQKGSVGRHGKIGPIGSKGEKGDSG 98 +PG G G KGD+G G PG G G G+ G+ G++G +G G GP GS G G+ G Sbjct: 653 LPGPPGLPGMKGDRGVVGEPGPKGEQGASGEEGEAGERGELGDIGLPGPKGSAGNPGEPG 712 Query: 99 DIGPPGPNGEPGL 111 GP G G PG+ Sbjct: 713 LRGPEGSRGLPGV 725 Score = 65.1 bits (157), Expect = 6e-11 Identities = 34/74 (45%), Positives = 41/74 (55%) Query: 39 VPGLKGDAGEKGDKGAPGRPGRVGPTGEKGDMGDKGQKGSVGRHGKIGPIGSKGEKGDSG 98 +PGL G G G KG G G GP GE+G G++G+ G G G IG G KG G+ G Sbjct: 650 LPGLPGPPGLPGMKGDRGVVGEPGPKGEQGASGEEGEAGERGELGDIGLPGPKGSAGNPG 709 Query: 99 DIGPPGPNGEPGLP 112 + G GP G GLP Sbjct: 710 EPGLRGPEGSRGLP 723 Score = 63.2 bits (152), Expect = 2e-10 Identities = 40/98 (40%), Positives = 46/98 (46%), Gaps = 14/98 (14%) Query: 29 GDDACSVQILVPGLKGDAGEKGDKGAPGR--PGRVGPTGEKGDMGDKGQKGSVGRHGKIG 86 G D I G KG+ G G +G PGR PG GP G G G+ G+ G VG G+ G Sbjct: 329 GPDGSPGSIGSKGQKGEPGVPGSRGFPGRGIPGPPGPPGTAGLPGELGRVGPVGDPGRRG 388 Query: 87 PIGSKGEKGDSGDIG------------PPGPNGEPGLP 112 P G G G G IG PPG +G PGLP Sbjct: 389 PPGPPGPPGPRGTIGFHDGDPLCPNACPPGRSGYPGLP 426 Score = 63.2 bits (152), Expect = 2e-10 Identities = 35/75 (46%), Positives = 41/75 (54%), Gaps = 3/75 (4%) Query: 41 GLKGDAGEKGDKGAPGRPGRVGPTGEKGDMGDKGQKGSVGRHGKIGP---IGSKGEKGDS 97 GL G+ G +G GAPG G+ GP GE G GD+G +G+ G G GP G G G Sbjct: 487 GLDGEPGPQGLPGAPGDQGQRGPPGEAGPKGDRGAEGARGIPGLPGPKGDTGLPGVDGRD 546 Query: 98 GDIGPPGPNGEPGLP 112 G G PG GEPG P Sbjct: 547 GIPGMPGTKGEPGKP 561 Score = 61.2 bits (147), Expect = 9e-10 Identities = 34/71 (47%), Positives = 40/71 (56%), Gaps = 5/71 (7%) Query: 45 DAGEKGDKGAPGRPGRVGPTGEKG---DMGDKGQKGSVGRHGKIGPIGSKGEKGDSGDIG 101 D+G G G PG PG GP GE G MG +G G G G +G G KG+ G+ G+ G Sbjct: 785 DSGATGLPGRPGPPGPPGPPGENGFPGQMGIRGLPGIKGPPGALGLRGPKGDLGEKGERG 844 Query: 102 PP--GPNGEPG 110 PP GPNG PG Sbjct: 845 PPGRGPNGLPG 855 Score = 60.8 bits (146), Expect = 1e-09 Identities = 33/80 (41%), Positives = 42/80 (52%), Gaps = 6/80 (7%) Query: 39 VPGLKGDAGEKGDKGAPGRPG------RVGPTGEKGDMGDKGQKGSVGRHGKIGPIGSKG 92 + G+ GD GEKG +G G PG G G++G G+ G KG G G G G G Sbjct: 473 ITGIVGDKGEKGARGLDGEPGPQGLPGAPGDQGQRGPPGEAGPKGDRGAEGARGIPGLPG 532 Query: 93 EKGDSGDIGPPGPNGEPGLP 112 KGD+G G G +G PG+P Sbjct: 533 PKGDTGLPGVDGRDGIPGMP 552 Score = 60.1 bits (144), Expect = 2e-09 Identities = 38/92 (41%), Positives = 42/92 (45%), Gaps = 6/92 (6%) Query: 21 PSGHPQPAGDDACSVQILVPGLKGDAGEKGDKGAPGRPGRVGPTGEKGDMGDKGQKGSVG 80 P G P GD G G+AG KGD+GA G G G G KGD G G G G Sbjct: 494 PQGLPGAPGDQGQR------GPPGEAGPKGDRGAEGARGIPGLPGPKGDTGLPGVDGRDG 547 Query: 81 RHGKIGPIGSKGEKGDSGDIGPPGPNGEPGLP 112 G G G G+ G GD G G G PG+P Sbjct: 548 IPGMPGTKGEPGKPGPPGDAGLQGLPGVPGIP 579 Score = 59.3 bits (142), Expect = 3e-09 Identities = 34/82 (41%), Positives = 40/82 (48%), Gaps = 9/82 (10%) Query: 40 PGLKGDAGEKGDKGAPGRPGRVGPTGEKGD---------MGDKGQKGSVGRHGKIGPIGS 90 PG +G G GD+G G PG GP G++G G KG G G G+ G G Sbjct: 492 PGPQGLPGAPGDQGQRGPPGEAGPKGDRGAEGARGIPGLPGPKGDTGLPGVDGRDGIPGM 551 Query: 91 KGEKGDSGDIGPPGPNGEPGLP 112 G KG+ G GPPG G GLP Sbjct: 552 PGTKGEPGKPGPPGDAGLQGLP 573 Score = 58.2 bits (139), Expect = 8e-09 Identities = 36/110 (32%), Positives = 47/110 (42%), Gaps = 21/110 (19%) Query: 23 GHPQPAGDDACSVQILVPGLKGDAGEKGDKGAPGRPG---------------------RV 61 G P P G ++ G GD G +G G PG PG R Sbjct: 361 GPPGPPGTAGLPGELGRVGPVGDPGRRGPPGPPGPPGPRGTIGFHDGDPLCPNACPPGRS 420 Query: 62 GPTGEKGDMGDKGQKGSVGRHGKIGPIGSKGEKGDSGDIGPPGPNGEPGL 111 G G G G KG KG +G G+ G G +G++G+ G++G GP G GL Sbjct: 421 GYPGLPGMRGHKGAKGEIGEPGRQGHKGEEGDQGELGEVGAQGPPGAQGL 470 Score = 57.8 bits (138), Expect = 1e-08 Identities = 30/68 (44%), Positives = 36/68 (52%) Query: 43 KGDAGEKGDKGAPGRPGRVGPTGEKGDMGDKGQKGSVGRHGKIGPIGSKGEKGDSGDIGP 102 +G GE+G G PG PG G G GD G KG G G G+ G G+ G+ G G G Sbjct: 268 RGPPGEQGPPGPPGPPGVPGIDGIDGDRGPKGPPGPPGPAGEPGKPGAPGKPGTPGADGL 327 Query: 103 PGPNGEPG 110 GP+G PG Sbjct: 328 TGPDGSPG 335 Score = 54.3 bits (129), Expect = 1e-07 Identities = 36/99 (36%), Positives = 46/99 (46%), Gaps = 25/99 (25%) Query: 39 VPGLKGDAGEKGDKGAPGRPGR---------------VGPTGEKGDMGDKGQKGSVGR-- 81 +PG G G G G G PG+ +G G KGD+G+KG++G GR Sbjct: 791 LPGRPGPPGPPGPPGENGFPGQMGIRGLPGIKGPPGALGLRGPKGDLGEKGERGPPGRGP 850 Query: 82 HGKIGPIG--------SKGEKGDSGDIGPPGPNGEPGLP 112 +G G IG S G G G+ GPPG G PG+P Sbjct: 851 NGLPGAIGLPGDPGPASYGRNGRDGERGPPGVAGIPGVP 889 Score = 52.4 bits (124), Expect = 4e-07 Identities = 29/83 (34%), Positives = 37/83 (44%), Gaps = 15/83 (18%) Query: 45 DAGEKGDKGAPGRP---------------GRVGPTGEKGDMGDKGQKGSVGRHGKIGPIG 89 + G G++G PG P G GP G G G+ G+ G+ G+ G G G Sbjct: 267 ERGPPGEQGPPGPPGPPGVPGIDGIDGDRGPKGPPGPPGPAGEPGKPGAPGKPGTPGADG 326 Query: 90 SKGEKGDSGDIGPPGPNGEPGLP 112 G G G IG G GEPG+P Sbjct: 327 LTGPDGSPGSIGSKGQKGEPGVP 349 Score = 52.0 bits (123), Expect = 5e-07 Identities = 40/130 (30%), Positives = 50/130 (38%), Gaps = 39/130 (30%) Query: 22 SGHPQPAGDDACSVQILVPGLKGDAGEKGD------KGAPGRPGRVGPTGEKGDMGDKGQ 75 SG AG+ I +PG KG AG G+ +G+ G PG GP G G G +G+ Sbjct: 681 SGEEGEAGERGELGDIGLPGPKGSAGNPGEPGLRGPEGSRGLPGVEGPRGPPGPRGVQGE 740 Query: 76 KGSVGRHGKIGP---------------------------------IGSKGEKGDSGDIGP 102 +G+ G G GP G+ G G G GP Sbjct: 741 QGATGLPGVQGPPGRAPTDQHIKQVCMRVIQEHFAEMAASLKRPDSGATGLPGRPGPPGP 800 Query: 103 PGPNGEPGLP 112 PGP GE G P Sbjct: 801 PGPPGENGFP 810 Score = 50.4 bits (119), Expect = 2e-06 Identities = 26/58 (44%), Positives = 32/58 (55%), Gaps = 3/58 (5%) Query: 58 PGRVGP---TGEKGDMGDKGQKGSVGRHGKIGPIGSKGEKGDSGDIGPPGPNGEPGLP 112 P R+ P T E+G G++G G G G G G G++G G GPPGP GEPG P Sbjct: 256 PARITPSQTTDERGPPGEQGPPGPPGPPGVPGIDGIDGDRGPKGPPGPPGPAGEPGKP 313 Score = 41.2 bits (95), Expect = 0.001 Identities = 31/105 (29%), Positives = 37/105 (35%), Gaps = 33/105 (31%) Query: 39 VPGLKGDAGEKGDKGAPGRPGRVGPTGEKGDMG--------------------------- 71 +PG++G G G +G G G G G +G G Sbjct: 722 LPGVEGPRGPPGPRGVQGEQGATGLPGVQGPPGRAPTDQHIKQVCMRVIQEHFAEMAASL 781 Query: 72 ---DKGQKGSVGRHGKIGPIGSKGEKGDSGDI---GPPGPNGEPG 110 D G G GR G GP G GE G G + G PG G PG Sbjct: 782 KRPDSGATGLPGRPGPPGPPGPPGENGFPGQMGIRGLPGIKGPPG 826 >gi|89142737 alpha 3 type IV collagen isoform 5 precursor [Homo sapiens] Length = 1424 Score = 80.1 bits (196), Expect = 2e-15 Identities = 44/90 (48%), Positives = 49/90 (54%), Gaps = 12/90 (13%) Query: 23 GHPQPAGDDACSVQILVPGLKGDAGEKGDKGAPGRPGRVGPTGEKGDMGDKGQKGSVGRH 82 G P P GD PGL GD G+KG+ G PG PG +GP G + G G GS G Sbjct: 1065 GPPGPTGD---------PGLPGDMGKKGEMGQPGPPGHLGPAGPE---GAPGSPGSPGLP 1112 Query: 83 GKIGPIGSKGEKGDSGDIGPPGPNGEPGLP 112 GK GP G G KG G +GPPG G PGLP Sbjct: 1113 GKPGPHGDLGFKGIKGLLGPPGIRGPPGLP 1142 Score = 73.9 bits (180), Expect = 1e-13 Identities = 45/110 (40%), Positives = 52/110 (47%), Gaps = 27/110 (24%) Query: 23 GHPQPAGDDACSVQILVPGLKGDAGEKGDKGAPGRPGRVGPTGE---------KGDMGDK 73 GHP P G PG GD G G GAPG PG GP G+ KG+ G+ Sbjct: 1274 GHPGPKGP---------PGTAGDMGPPGRLGAPGTPGLPGPRGDPGFQGFPGVKGEKGNP 1324 Query: 74 GQKGSVGRHGKIGPIGSKGEKGDSGDI---------GPPGPNGEPGLPCE 114 G GS+G G IGP G G +GD G + GPPG GEPG+ E Sbjct: 1325 GFLGSIGPPGPIGPKGPPGVRGDPGTLKIISLPGSPGPPGTPGEPGMQGE 1374 Score = 70.5 bits (171), Expect = 1e-12 Identities = 37/76 (48%), Positives = 45/76 (59%), Gaps = 5/76 (6%) Query: 40 PGLKGDAGEKGDKGAPG-----RPGRVGPTGEKGDMGDKGQKGSVGRHGKIGPIGSKGEK 94 PGL G G +GDKG PG RPG GPTG+ G GD G+KG +G+ G G +G G + Sbjct: 1041 PGLPGIHGLQGDKGEPGYSEGTRPGPPGPTGDPGLPGDMGKKGEMGQPGPPGHLGPAGPE 1100 Query: 95 GDSGDIGPPGPNGEPG 110 G G G PG G+PG Sbjct: 1101 GAPGSPGSPGLPGKPG 1116 Score = 68.9 bits (167), Expect = 4e-12 Identities = 40/93 (43%), Positives = 49/93 (52%), Gaps = 3/93 (3%) Query: 23 GHPQPAGDDACSVQILVP-GLKGDAGEKGDKGAPGRPGRVGPTGEKGDMGDKGQKGSVGR 81 G P PAG+ + + P G +G+ G +G KG G PG G G KG MGD G +G G Sbjct: 1161 GIPGPAGEKGETGLLRAPPGPRGNPGAQGAKGDRGAPGFPGLPGRKGAMGDAGPRGPTGI 1220 Query: 82 HGKIGPIGSKGE--KGDSGDIGPPGPNGEPGLP 112 G GP G G G +G+ GPPG G PG P Sbjct: 1221 EGFPGPPGLPGAIIPGQTGNRGPPGSRGSPGAP 1253 Score = 68.9 bits (167), Expect = 4e-12 Identities = 39/91 (42%), Positives = 46/91 (50%), Gaps = 4/91 (4%) Query: 23 GHPQPAGDDACSVQILVPGLKGDAGEKGDKGAPGRPGRVGPTGEKGDMGDKGQKGSVGRH 82 G P P GD PG+KG+ G G G+ G PG +GP G G GD G + Sbjct: 1301 GLPGPRGDPGFQG---FPGVKGEKGNPGFLGSIGPPGPIGPKGPPGVRGDPGTLKIISLP 1357 Query: 83 GKIGPIGSKGEKGDSGDIGPPGPNGEPGLPC 113 G GP G+ GE G G+ GPPGP G G PC Sbjct: 1358 GSPGPPGTPGEPGMQGEPGPPGPPGNLG-PC 1387 Score = 68.6 bits (166), Expect = 6e-12 Identities = 37/88 (42%), Positives = 47/88 (53%), Gaps = 5/88 (5%) Query: 23 GHPQPAGDDACSVQILVPGLKGDAGEKGDKGAPGRPGRVGPTGEKGDMGDKGQKGSVGRH 82 G P P G ++PG G+ G G +G+PG PG GP G +G KG KGS+G Sbjct: 1222 GFPGPPGLPGA----IIPGQTGNRGPPGSRGSPGAPGPPGPPGSH-VIGIKGDKGSMGHP 1276 Query: 83 GKIGPIGSKGEKGDSGDIGPPGPNGEPG 110 G GP G+ G+ G G +G PG G PG Sbjct: 1277 GPKGPPGTAGDMGPPGRLGAPGTPGLPG 1304 Score = 68.2 bits (165), Expect = 7e-12 Identities = 39/88 (44%), Positives = 46/88 (52%), Gaps = 15/88 (17%) Query: 40 PGLKGDAG---EKGDKGAPGRPGR---------VGPTGEKGDMGDKGQKGSVGRHG---K 84 PGLKG AG EKG++G PG PG GP G +GD+G G G G G Sbjct: 957 PGLKGFAGNPGEKGNRGVPGMPGLKGLKGLPGPAGPPGPRGDLGSTGNPGEPGLRGIPGS 1016 Query: 85 IGPIGSKGEKGDSGDIGPPGPNGEPGLP 112 +G +G G KG G +G PG G PGLP Sbjct: 1017 MGNMGMPGSKGKRGTLGFPGRAGRPGLP 1044 Score = 67.8 bits (164), Expect = 1e-11 Identities = 37/81 (45%), Positives = 44/81 (54%), Gaps = 9/81 (11%) Query: 40 PGLKGDAGEKGDKGAPGRPGRVGPTGEKGDMGDKGQKGSVGRHGKIGPIGSKGEKGDSGD 99 PG+ G GE G G G PG +GP G G+ G GQ+GS G G G G+ G KG+ GD Sbjct: 879 PGILGPPGEDGVIGMMGFPGAIGPPGPPGNPGTPGQRGSPGIPGVKGQRGTPGAKGEQGD 938 Query: 100 IGPPGPN---------GEPGL 111 G PGP+ GEPGL Sbjct: 939 KGNPGPSEISHVIGDKGEPGL 959 Score = 67.4 bits (163), Expect = 1e-11 Identities = 40/98 (40%), Positives = 48/98 (48%), Gaps = 5/98 (5%) Query: 23 GHPQPAGDDACSVQILVPGLKGDAGEKGDKGAP-----GRPGRVGPTGEKGDMGDKGQKG 77 G P G C ++ PGL G G G KG P G PG G GE+G+ G+ G+ G Sbjct: 712 GFPGTKGSLGCPGKMGEPGLPGKPGLPGAKGEPAVAMPGGPGTPGFPGERGNSGEHGEIG 771 Query: 78 SVGRHGKIGPIGSKGEKGDSGDIGPPGPNGEPGLPCEC 115 G G G G++G G GD G PGP GE G P C Sbjct: 772 LPGLPGLPGTPGNEGLDGPRGDPGQPGPPGEQGPPGRC 809 Score = 66.2 bits (160), Expect = 3e-11 Identities = 42/97 (43%), Positives = 47/97 (48%), Gaps = 7/97 (7%) Query: 21 PSGHPQPAGDDACSVQILVPGL------KGDAGEKGDKGAPGRPGRVGPTGEKGDMGDKG 74 P GH PAG + PGL GD G KG KG G PG GP G G G G Sbjct: 1090 PPGHLGPAGPEGAPGSPGSPGLPGKPGPHGDLGFKGIKGLLGPPGIRGPPGLPGFPGSPG 1149 Query: 75 QKGSVGRHGKIGPIGSKGEKGDSGDI-GPPGPNGEPG 110 G G G+ G G GEKG++G + PPGP G PG Sbjct: 1150 PMGIRGDQGRDGIPGPAGEKGETGLLRAPPGPRGNPG 1186 Score = 66.2 bits (160), Expect = 3e-11 Identities = 41/87 (47%), Positives = 45/87 (51%), Gaps = 14/87 (16%) Query: 40 PGLKGD--AGEKGDKGAPGRPGRVGPTGEKGDMGDKGQKGSVGRHGKIGPIGS------- 90 PG G G KGDKG+ G PG GP G GDMG G+ G+ G G GP G Sbjct: 1256 PGPPGSHVIGIKGDKGSMGHPGPKGPPGTAGDMGPPGRLGAPGTPGLPGPRGDPGFQGFP 1315 Query: 91 --KGEKGDS---GDIGPPGPNGEPGLP 112 KGEKG+ G IGPPGP G G P Sbjct: 1316 GVKGEKGNPGFLGSIGPPGPIGPKGPP 1342 Score = 65.5 bits (158), Expect = 5e-11 Identities = 38/101 (37%), Positives = 48/101 (47%), Gaps = 9/101 (8%) Query: 21 PSGHPQPAGDDACSVQILVPGL--KGDAGEKGDKGAPGRPGRVGPTGEKGDM-------G 71 P G P G + PG +G+ G +G +G PG PG G G +G++ G Sbjct: 597 PPGDPGSPGSPGPAGPAGPPGYGPQGEPGLQGTQGVPGAPGPPGEAGPRGELSVSTPVPG 656 Query: 72 DKGQKGSVGRHGKIGPIGSKGEKGDSGDIGPPGPNGEPGLP 112 G G G G GP G G G GD G PGP+GEPG+P Sbjct: 657 PPGPPGPPGHPGPQGPPGIPGSLGKCGDPGLPGPDGEPGIP 697 Score = 65.5 bits (158), Expect = 5e-11 Identities = 43/107 (40%), Positives = 48/107 (44%), Gaps = 22/107 (20%) Query: 21 PSGHPQPAGDDACSVQILVPGLKGDAGEKGDKGAPGRPGRVG--------PTGEKGDMGD 72 P GHP P G PG+ G G+ GD G PG G G P G KGD G Sbjct: 663 PPGHPGPQGP---------PGIPGSLGKCGDPGLPGPDGEPGIPGIGFPGPPGPKGDQGF 713 Query: 73 KGQKGSVGRHGKIGPIGSKGEKGDSGDIGP-----PGPNGEPGLPCE 114 G KGS+G GK+G G G+ G G G PG G PG P E Sbjct: 714 PGTKGSLGCPGKMGEPGLPGKPGLPGAKGEPAVAMPGGPGTPGFPGE 760 Score = 64.7 bits (156), Expect = 8e-11 Identities = 34/81 (41%), Positives = 41/81 (50%), Gaps = 9/81 (11%) Query: 39 VPGLKGDAGEKGDKGAPGRPGRVGPTGEKGDMGDKGQKGSV---------GRHGKIGPIG 89 VPG G G KG++G PG G G G+KGD+G G +G G G GP G Sbjct: 304 VPGFPGSEGVKGNRGFPGLMGEDGIKGQKGDIGPPGFRGPTEYYDTYQEKGDEGTPGPPG 363 Query: 90 SKGEKGDSGDIGPPGPNGEPG 110 +G +G G GPPG G PG Sbjct: 364 PRGARGPQGPSGPPGVPGSPG 384 Score = 64.7 bits (156), Expect = 8e-11 Identities = 36/91 (39%), Positives = 45/91 (49%), Gaps = 17/91 (18%) Query: 39 VPGLKGDAGEKGDKGAPGRPGRVGPTGEKGDMGDKGQKGSVGRHGKIGPIGSKGE----- 93 +PG G G +GD G+ G PG G G G MG+ G GS G+ G +G G G Sbjct: 986 LPGPAGPPGPRGDLGSTGNPGEPGLRGIPGSMGNMGMPGSKGKRGTLGFPGRAGRPGLPG 1045 Query: 94 ----KGDSGD--------IGPPGPNGEPGLP 112 +GD G+ GPPGP G+PGLP Sbjct: 1046 IHGLQGDKGEPGYSEGTRPGPPGPTGDPGLP 1076 Score = 64.3 bits (155), Expect = 1e-10 Identities = 36/85 (42%), Positives = 41/85 (48%), Gaps = 12/85 (14%) Query: 40 PGLKGDAGEKG------------DKGAPGRPGRVGPTGEKGDMGDKGQKGSVGRHGKIGP 87 PG KG+ G+KG DKG PG G G GEKG+ G G G G G GP Sbjct: 930 PGAKGEQGDKGNPGPSEISHVIGDKGEPGLKGFAGNPGEKGNRGVPGMPGLKGLKGLPGP 989 Query: 88 IGSKGEKGDSGDIGPPGPNGEPGLP 112 G G +GD G G PG G G+P Sbjct: 990 AGPPGPRGDLGSTGNPGEPGLRGIP 1014 Score = 64.3 bits (155), Expect = 1e-10 Identities = 32/79 (40%), Positives = 38/79 (48%) Query: 21 PSGHPQPAGDDACSVQILVPGLKGDAGEKGDKGAPGRPGRVGPTGEKGDMGDKGQKGSVG 80 P G P GD I +PG G G G+ G G PG GP G G G +G+ G G Sbjct: 1338 PKGPPGVRGDPGTLKIISLPGSPGPPGTPGEPGMQGEPGPPGPPGNLGPCGPRGKPGKDG 1397 Query: 81 RHGKIGPIGSKGEKGDSGD 99 + G GP G KG KG G+ Sbjct: 1398 KPGTPGPAGEKGNKGSKGE 1416 Score = 63.5 bits (153), Expect = 2e-10 Identities = 39/99 (39%), Positives = 48/99 (48%), Gaps = 11/99 (11%) Query: 23 GHPQPAG--DDACSVQILVPGLKGDAGEKGDKGAPGRPGRVGPTGEKGDMGDKGQKGSVG 80 G P P+G ++ + PG G G+ G G PG PG G G +G G G+ G G Sbjct: 271 GPPGPSGLPGESYGSEKGAPGDPGLQGKPGKDGVPGFPGSEGVKGNRGFPGLMGEDGIKG 330 Query: 81 RHGKIGPIGSKG---------EKGDSGDIGPPGPNGEPG 110 + G IGP G +G EKGD G GPPGP G G Sbjct: 331 QKGDIGPPGFRGPTEYYDTYQEKGDEGTPGPPGPRGARG 369 Score = 63.5 bits (153), Expect = 2e-10 Identities = 37/92 (40%), Positives = 42/92 (45%), Gaps = 6/92 (6%) Query: 27 PAGDDACSVQILVPGLKGDAGEKGDKGAPGRPGRVGPTGEKGDMGDKGQKGSVGRHGKIG 86 P G+D + PG G G G+ G PG+ G G G KG G G KG G G G Sbjct: 884 PPGEDGVIGMMGFPGAIGPPGPPGNPGTPGQRGSPGIPGVKGQRGTPGAKGEQGDKGNPG 943 Query: 87 P------IGSKGEKGDSGDIGPPGPNGEPGLP 112 P IG KGE G G G PG G G+P Sbjct: 944 PSEISHVIGDKGEPGLKGFAGNPGEKGNRGVP 975 Score = 63.2 bits (152), Expect = 2e-10 Identities = 40/98 (40%), Positives = 44/98 (44%), Gaps = 5/98 (5%) Query: 18 SLLPSGHPQPAGDDACSVQILVPGLKGDAGEKGDKGAPGRPGRVGPTGEKGDMGDKGQKG 77 +L P G GD Q GL G G G KG PG G + +GEKGD G G G Sbjct: 543 TLQPEGQVGVPGDPGLRGQPGRKGLDGIPGTPGVKGLPGPKGELALSGEKGDQGPPGDPG 602 Query: 78 SVGRHGKIGP-----IGSKGEKGDSGDIGPPGPNGEPG 110 S G G GP G +GE G G G PG G PG Sbjct: 603 SPGSPGPAGPAGPPGYGPQGEPGLQGTQGVPGAPGPPG 640 Score = 63.2 bits (152), Expect = 2e-10 Identities = 41/103 (39%), Positives = 47/103 (45%), Gaps = 11/103 (10%) Query: 21 PSGHPQ--PAGDDACSVQILVPGLKGDAGEKGDKG-------APGRPGRVGPTGEKGDMG 71 P+G P P G+ VPG G GE G +G PG PG GP G G G Sbjct: 612 PAGPPGYGPQGEPGLQGTQGVPGAPGPPGEAGPRGELSVSTPVPGPPGPPGPPGHPGPQG 671 Query: 72 DKGQKGSVGRHGKIGPIGSKGEKG--DSGDIGPPGPNGEPGLP 112 G GS+G+ G G G GE G G GPPGP G+ G P Sbjct: 672 PPGIPGSLGKCGDPGLPGPDGEPGIPGIGFPGPPGPKGDQGFP 714 Score = 63.2 bits (152), Expect = 2e-10 Identities = 38/92 (41%), Positives = 44/92 (47%), Gaps = 14/92 (15%) Query: 23 GHPQPAGDDACSVQILVPGL--KGDAGEKGDKGAPGRPGRVGPTGEKGDMGDKGQKGSVG 80 G P GD +PGL G GE G G PG G +GP G++G G+ G G G Sbjct: 833 GKTGPKGDPG------IPGLDRSGFPGETGSPGIPGHQGEMGPLGQRGYPGNPGILGPPG 886 Query: 81 RHGKIGPIGSKGEKGDSGDIGPPGPNGEPGLP 112 G IG +G G IGPPGP G PG P Sbjct: 887 EDGVIGMMGFPGA------IGPPGPPGNPGTP 912 Score = 63.2 bits (152), Expect = 2e-10 Identities = 38/95 (40%), Positives = 47/95 (49%), Gaps = 3/95 (3%) Query: 21 PSGHPQPAGDDACSVQILVPGLKGD---AGEKGDKGAPGRPGRVGPTGEKGDMGDKGQKG 77 P+G P GD ++ PG G AG +G G+PG PG G G GD+G KG KG Sbjct: 1069 PTGDPGLPGDMGKKGEMGQPGPPGHLGPAGPEGAPGSPGSPGLPGKPGPHGDLGFKGIKG 1128 Query: 78 SVGRHGKIGPIGSKGEKGDSGDIGPPGPNGEPGLP 112 +G G GP G G G G +G G G G+P Sbjct: 1129 LLGPPGIRGPPGLPGFPGSPGPMGIRGDQGRDGIP 1163 Score = 61.2 bits (147), Expect = 9e-10 Identities = 37/88 (42%), Positives = 42/88 (47%), Gaps = 4/88 (4%) Query: 27 PAGDDACSV----QILVPGLKGDAGEKGDKGAPGRPGRVGPTGEKGDMGDKGQKGSVGRH 82 PA C Q G KG+ GEKG G PG PG+ G TG +G G +G KG G Sbjct: 25 PAASKGCVCKDKGQCFCDGAKGEKGEKGFPGPPGSPGQKGFTGPEGLPGPQGPKGFPGLP 84 Query: 83 GKIGPIGSKGEKGDSGDIGPPGPNGEPG 110 G G G +G G G G PG G PG Sbjct: 85 GLTGSKGVRGISGLPGFSGSPGLPGTPG 112 Score = 60.8 bits (146), Expect = 1e-09 Identities = 35/80 (43%), Positives = 43/80 (53%), Gaps = 7/80 (8%) Query: 40 PGLKGDAGEKGDKGAPGRP-GRVGPTGEKGDMGDKGQKG------SVGRHGKIGPIGSKG 92 PG +GD G KG+KG +P G+VG G+ G G G+KG + G G GP G Sbjct: 528 PGAQGDPGLKGEKGETLQPEGQVGVPGDPGLRGQPGRKGLDGIPGTPGVKGLPGPKGELA 587 Query: 93 EKGDSGDIGPPGPNGEPGLP 112 G+ GD GPPG G PG P Sbjct: 588 LSGEKGDQGPPGDPGSPGSP 607 Score = 60.8 bits (146), Expect = 1e-09 Identities = 41/111 (36%), Positives = 49/111 (44%), Gaps = 24/111 (21%) Query: 23 GHPQPAGDDACSVQILVPGLKGDAGEKGDKGAPGRPGRVGPTGEKG--DMGDKGQKGSVG 80 G P P G+ A S G KGD G GD G+PG PG GP G G G+ G +G+ G Sbjct: 578 GLPGPKGELALS------GEKGDQGPPGDPGSPGSPGPAGPAGPPGYGPQGEPGLQGTQG 631 Query: 81 RHGKIGPIGSKGEKGD----------------SGDIGPPGPNGEPGLPCEC 115 G GP G G +G+ G GP GP G PG +C Sbjct: 632 VPGAPGPPGEAGPRGELSVSTPVPGPPGPPGPPGHPGPQGPPGIPGSLGKC 682 Score = 60.8 bits (146), Expect = 1e-09 Identities = 42/112 (37%), Positives = 51/112 (45%), Gaps = 10/112 (8%) Query: 9 GVLISLAFLSLL-PSGHPQPAGDDACSVQILVPGLKGDAGEKGDKGAPGRPGRVGPT--- 64 GV+ + F + P G P G +PG+KG G G KG G G GP+ Sbjct: 889 GVIGMMGFPGAIGPPGPPGNPGTPGQRGSPGIPGVKGQRGTPGAKGEQGDKGNPGPSEIS 948 Query: 65 ---GEKGDMGDK---GQKGSVGRHGKIGPIGSKGEKGDSGDIGPPGPNGEPG 110 G+KG+ G K G G G G G G KG KG G GPPGP G+ G Sbjct: 949 HVIGDKGEPGLKGFAGNPGEKGNRGVPGMPGLKGLKGLPGPAGPPGPRGDLG 1000 Score = 60.8 bits (146), Expect = 1e-09 Identities = 32/77 (41%), Positives = 39/77 (50%), Gaps = 6/77 (7%) Query: 40 PGLKGDAGEKGDKGAPGR------PGRVGPTGEKGDMGDKGQKGSVGRHGKIGPIGSKGE 93 PG G G G +G PG PG GP G G+ G +G+ G G G +GP G +G+ Sbjct: 1333 PGPIGPKGPPGVRGDPGTLKIISLPGSPGPPGTPGEPGMQGEPGPPGPPGNLGPCGPRGK 1392 Query: 94 KGDSGDIGPPGPNGEPG 110 G G G PGP GE G Sbjct: 1393 PGKDGKPGTPGPAGEKG 1409 Score = 60.1 bits (144), Expect = 2e-09 Identities = 44/110 (40%), Positives = 52/110 (47%), Gaps = 26/110 (23%) Query: 22 SGHPQPAGDDACSVQILVPGLKGDA-GEKGDKGAPGRPGRVGPTG--------EKGDMGD 72 +G P P G V + P + D GEKGDKGA G PG GP+G EKG GD Sbjct: 235 TGPPGPPG--TVIVTLTGPDNRTDLKGEKGDKGAMGEPGPPGPSGLPGESYGSEKGAPGD 292 Query: 73 KGQKGSVGRHGKIGPIGSKGEKGD---------------SGDIGPPGPNG 107 G +G G+ G G GS+G KG+ GDIGPPG G Sbjct: 293 PGLQGKPGKDGVPGFPGSEGVKGNRGFPGLMGEDGIKGQKGDIGPPGFRG 342 Score = 60.1 bits (144), Expect = 2e-09 Identities = 31/73 (42%), Positives = 38/73 (52%) Query: 40 PGLKGDAGEKGDKGAPGRPGRVGPTGEKGDMGDKGQKGSVGRHGKIGPIGSKGEKGDSGD 99 PG G G++G G PG G+ G G KG+ GDKG G IG G G KG +G+ Sbjct: 906 PGNPGTPGQRGSPGIPGVKGQRGTPGAKGEQGDKGNPGPSEISHVIGDKGEPGLKGFAGN 965 Query: 100 IGPPGPNGEPGLP 112 G G G PG+P Sbjct: 966 PGEKGNRGVPGMP 978 Score = 58.5 bits (140), Expect = 6e-09 Identities = 34/74 (45%), Positives = 38/74 (51%), Gaps = 3/74 (4%) Query: 41 GLKGDAGEKGDKGAPGRPGRV--GPTGEKGDMGDKGQKGSVGRHGKIGPIGSKGEKGDSG 98 G +GD G+ G G G PGR GP G +G G G KG GR GK GP G G G Sbjct: 789 GPRGDPGQPGPPGEQGPPGRCIEGPRGAQGLPGLNGLKGQQGRRGKTGPKGDPGIPGLDR 848 Query: 99 DIGPPGPNGEPGLP 112 G PG G PG+P Sbjct: 849 S-GFPGETGSPGIP 861 Score = 58.2 bits (139), Expect = 8e-09 Identities = 40/93 (43%), Positives = 44/93 (47%), Gaps = 21/93 (22%) Query: 40 PGLKGDAGEK----------GDKGAPGRPGR------VGPTGEKGDMGDKGQ---KGSVG 80 PGLKG+ GE GD G G+PGR G G KG G KG+ G G Sbjct: 534 PGLKGEKGETLQPEGQVGVPGDPGLRGQPGRKGLDGIPGTPGVKGLPGPKGELALSGEKG 593 Query: 81 RHGKIGPIGSKGEKGDSGDIGPP--GPNGEPGL 111 G G GS G G +G GPP GP GEPGL Sbjct: 594 DQGPPGDPGSPGSPGPAGPAGPPGYGPQGEPGL 626 Score = 57.4 bits (137), Expect = 1e-08 Identities = 34/69 (49%), Positives = 38/69 (55%), Gaps = 3/69 (4%) Query: 44 GDAGEKGDKGAPGRPGRVGPTGEKGDMGDKGQKGSVGRHGKIGPIGSKGEKGDSGDIGPP 103 G GEKG+KG PG PG G G G G G +G G G G GSKG +G S G P Sbjct: 43 GAKGEKGEKGFPGPPGSPGQKGFTGPEGLPGPQGPKGFPGLPGLTGSKGVRGIS---GLP 99 Query: 104 GPNGEPGLP 112 G +G PGLP Sbjct: 100 GFSGSPGLP 108 Score = 56.6 bits (135), Expect = 2e-08 Identities = 34/77 (44%), Positives = 38/77 (49%), Gaps = 4/77 (5%) Query: 40 PGLKGDAGEKGDKGAPGRPGRVGPTGEKGDMGDKGQKGSVGRHGKIGPIGSKGEKGDS-- 97 PGL G G G KG PGR G G G G G+ G G G G G G KGEKG++ Sbjct: 486 PGLPGLPGLHGVKGIPGRQGAAGLKGSPGSPGNTGLPGFPGFPGAQGDPGLKGEKGETLQ 545 Query: 98 --GDIGPPGPNGEPGLP 112 G +G PG G G P Sbjct: 546 PEGQVGVPGDPGLRGQP 562 Score = 56.2 bits (134), Expect = 3e-08 Identities = 35/92 (38%), Positives = 41/92 (44%), Gaps = 12/92 (13%) Query: 21 PSGHPQPAGDDACSVQILVPGLKGDAGEKGDKGAPGRPGRVGPTGEKGDMGDKGQKGSVG 80 P G P P G PGL G G KG +G G P G G G G G+ G Sbjct: 68 PEGLPGPQGPKG------FPGLPGLTGSKGVRGISGLP------GFSGSPGLPGTPGNTG 115 Query: 81 RHGKIGPIGSKGEKGDSGDIGPPGPNGEPGLP 112 +G +G G G KG+ G G PG G PG+P Sbjct: 116 PYGLVGVPGCSGSKGEQGFPGLPGTLGYPGIP 147 Score = 55.8 bits (133), Expect = 4e-08 Identities = 40/117 (34%), Positives = 50/117 (42%), Gaps = 37/117 (31%) Query: 35 VQILVPGLKGDAGEKGDKGAPGRPGR------------------VGPTGEKGDMGD---- 72 +++ G G G G +G PG PG +GP G KG MG+ Sbjct: 165 IELDAKGDPGLPGAPGPQGLPGPPGFPGPVGPPGPPGFFGFPGAMGPRGPKGHMGERVIG 224 Query: 73 -KGQKGSVGRHGKIGPIGS--------------KGEKGDSGDIGPPGPNGEPGLPCE 114 KG++G G G GP G+ KGEKGD G +G PGP G GLP E Sbjct: 225 HKGERGVKGLTGPPGPPGTVIVTLTGPDNRTDLKGEKGDKGAMGEPGPPGPSGLPGE 281 Score = 55.1 bits (131), Expect = 6e-08 Identities = 46/120 (38%), Positives = 50/120 (41%), Gaps = 28/120 (23%) Query: 21 PSGHPQPAGDDACSVQILV-----PGLKGDAGEKGDKG--------------APGRPGRV 61 PSG P G S L PGLKG GE+G G +PG PG Sbjct: 373 PSGPPGVPGSPGSSRPGLRGAPGWPGLKGSKGERGRPGKDAMGTPGSPGCAGSPGLPGSP 432 Query: 62 GPTGEKGDM-------GDKGQKGSVGRHGKIGPIGSKGEKGDSGDIGP--PGPNGEPGLP 112 GP G GD+ GD G G +G G G G KGE G P PGP G PGLP Sbjct: 433 GPPGPPGDIVFRKGPPGDHGLPGYLGSPGIPGVDGPKGEPGLLCTQCPYIPGPPGLPGLP 492 Score = 54.3 bits (129), Expect = 1e-07 Identities = 37/99 (37%), Positives = 41/99 (41%), Gaps = 31/99 (31%) Query: 40 PGLKGDAGEKGDKGAP--------------------GRPGRVGPTGEKGDMGDKGQKGSV 79 PG+ G AG KG KGAP G G GP G G +G G G Sbjct: 144 PGIPGAAGLKGQKGAPAKEEDIELDAKGDPGLPGAPGPQGLPGPPGFPGPVGPPGPPGFF 203 Query: 80 GRHGKIGP-----------IGSKGEKGDSGDIGPPGPNG 107 G G +GP IG KGE+G G GPPGP G Sbjct: 204 GFPGAMGPRGPKGHMGERVIGHKGERGVKGLTGPPGPPG 242 Score = 52.8 bits (125), Expect = 3e-07 Identities = 35/84 (41%), Positives = 40/84 (47%), Gaps = 10/84 (11%) Query: 41 GLKGDAGEKGDKGAPGRPGRVGPTGEKGDMGDKGQ----KGSVGRHGKIGPIGSKGEKGD 96 GLKG G G+ G PG PG G G+ G G+KG+ +G VG G G G G KG Sbjct: 508 GLKGSPGSPGNTGLPGFPGFPGAQGDPGLKGEKGETLQPEGQVGVPGDPGLRGQPGRKGL 567 Query: 97 SGDIGPPG------PNGEPGLPCE 114 G G PG P GE L E Sbjct: 568 DGIPGTPGVKGLPGPKGELALSGE 591 Score = 52.4 bits (124), Expect = 4e-07 Identities = 32/71 (45%), Positives = 34/71 (47%) Query: 40 PGLKGDAGEKGDKGAPGRPGRVGPTGEKGDMGDKGQKGSVGRHGKIGPIGSKGEKGDSGD 99 PG G G+KG G G PG GP G G G G KG G G G GS G G G+ Sbjct: 54 PGPPGSPGQKGFTGPEGLPGPQGPKGFPGLPGLTGSKGVRGISGLPGFSGSPGLPGTPGN 113 Query: 100 IGPPGPNGEPG 110 GP G G PG Sbjct: 114 TGPYGLVGVPG 124 Score = 51.2 bits (121), Expect = 9e-07 Identities = 42/123 (34%), Positives = 52/123 (42%), Gaps = 25/123 (20%) Query: 23 GHPQPAGDDACSVQILVPGLKGDAGEKGDKGAPGRPGRVGPTGEKGDM------------ 70 G P P GD + G GD G G G+PG PG GP GE G + Sbjct: 433 GPPGPPGDI-----VFRKGPPGDHGLPGYLGSPGIPGVDGPKGEPGLLCTQCPYIPGPPG 487 Query: 71 -----GDKGQKGSVGRHGKIGPIGSKGEKGDSG---DIGPPGPNGEPGLPCECSQLRKAI 122 G G KG GR G G GS G G++G G PG G+PGL E + + Sbjct: 488 LPGLPGLHGVKGIPGRQGAAGLKGSPGSPGNTGLPGFPGFPGAQGDPGLKGEKGETLQPE 547 Query: 123 GEM 125 G++ Sbjct: 548 GQV 550 Score = 50.1 bits (118), Expect = 2e-06 Identities = 32/81 (39%), Positives = 37/81 (45%), Gaps = 1/81 (1%) Query: 33 CSVQILVPGLKGDAGEKGDKGAPGRPGRVGPTGEKGDMGDKGQKGSVGRHGKIGPIGSKG 92 C+ +PG G G G G G PGR G G KG G G G G G G G G Sbjct: 476 CTQCPYIPGPPGLPGLPGLHGVKGIPGRQGAAGLKGSPGSPGNTGLPGFPGFPGAQGDPG 535 Query: 93 EKGDSGD-IGPPGPNGEPGLP 112 KG+ G+ + P G G PG P Sbjct: 536 LKGEKGETLQPEGQVGVPGDP 556 Score = 48.5 bits (114), Expect = 6e-06 Identities = 35/82 (42%), Positives = 37/82 (45%), Gaps = 13/82 (15%) Query: 40 PGLKGD---AGEKGDKGAPGRPGRVGPT------GEKGDMGDKGQKGSVGRHGKIGPIGS 90 PGL G+ G+KGD G PG GPT EKGD G G G G G GP G Sbjct: 320 PGLMGEDGIKGQKGDIGPPGFR---GPTEYYDTYQEKGDEGTPGPPGPRGARGPQGPSGP 376 Query: 91 KGEKGDSGDIGPPGPNGEPGLP 112 G G G PG G PG P Sbjct: 377 PGVPGSPGS-SRPGLRGAPGWP 397 Score = 44.7 bits (104), Expect = 9e-05 Identities = 23/57 (40%), Positives = 28/57 (49%), Gaps = 9/57 (15%) Query: 23 GHPQPAGDDACSVQILVPGLKGDAGEKGDKGAPGRPGRVGPTGEKGDMGDKGQKGSV 79 G P P G PG G G +G G G+PG GP GEKG+ G KG+ S+ Sbjct: 1373 GEPGPPGP---------PGNLGPCGPRGKPGKDGKPGTPGPAGEKGNKGSKGEPESL 1420 Score = 43.9 bits (102), Expect = 1e-04 Identities = 22/47 (46%), Positives = 25/47 (53%) Query: 66 EKGDMGDKGQKGSVGRHGKIGPIGSKGEKGDSGDIGPPGPNGEPGLP 112 +KG G KG G G GP GS G+KG +G G PGP G G P Sbjct: 35 DKGQCFCDGAKGEKGEKGFPGPPGSPGQKGFTGPEGLPGPQGPKGFP 81 >gi|89142735 alpha 3 type IV collagen isoform 4 precursor [Homo sapiens] Length = 1494 Score = 80.1 bits (196), Expect = 2e-15 Identities = 44/90 (48%), Positives = 49/90 (54%), Gaps = 12/90 (13%) Query: 23 GHPQPAGDDACSVQILVPGLKGDAGEKGDKGAPGRPGRVGPTGEKGDMGDKGQKGSVGRH 82 G P P GD PGL GD G+KG+ G PG PG +GP G + G G GS G Sbjct: 1065 GPPGPTGD---------PGLPGDMGKKGEMGQPGPPGHLGPAGPE---GAPGSPGSPGLP 1112 Query: 83 GKIGPIGSKGEKGDSGDIGPPGPNGEPGLP 112 GK GP G G KG G +GPPG G PGLP Sbjct: 1113 GKPGPHGDLGFKGIKGLLGPPGIRGPPGLP 1142 Score = 77.8 bits (190), Expect = 9e-15 Identities = 39/91 (42%), Positives = 46/91 (50%) Query: 21 PSGHPQPAGDDACSVQILVPGLKGDAGEKGDKGAPGRPGRVGPTGEKGDMGDKGQKGSVG 80 P G P GD I +PG G G G+ G G PG GP G G G +G+ G G Sbjct: 1338 PKGPPGVRGDPGTLKIISLPGSPGPPGTPGEPGMQGEPGPPGPPGNLGPCGPRGKPGKDG 1397 Query: 81 RHGKIGPIGSKGEKGDSGDIGPPGPNGEPGL 111 + G GP G KG KG G+ GP G +G PGL Sbjct: 1398 KPGTPGPAGEKGNKGSKGEPGPAGSDGLPGL 1428 Score = 73.9 bits (180), Expect = 1e-13 Identities = 45/110 (40%), Positives = 52/110 (47%), Gaps = 27/110 (24%) Query: 23 GHPQPAGDDACSVQILVPGLKGDAGEKGDKGAPGRPGRVGPTGE---------KGDMGDK 73 GHP P G PG GD G G GAPG PG GP G+ KG+ G+ Sbjct: 1274 GHPGPKGP---------PGTAGDMGPPGRLGAPGTPGLPGPRGDPGFQGFPGVKGEKGNP 1324 Query: 74 GQKGSVGRHGKIGPIGSKGEKGDSGDI---------GPPGPNGEPGLPCE 114 G GS+G G IGP G G +GD G + GPPG GEPG+ E Sbjct: 1325 GFLGSIGPPGPIGPKGPPGVRGDPGTLKIISLPGSPGPPGTPGEPGMQGE 1374 Score = 70.5 bits (171), Expect = 1e-12 Identities = 37/76 (48%), Positives = 45/76 (59%), Gaps = 5/76 (6%) Query: 40 PGLKGDAGEKGDKGAPG-----RPGRVGPTGEKGDMGDKGQKGSVGRHGKIGPIGSKGEK 94 PGL G G +GDKG PG RPG GPTG+ G GD G+KG +G+ G G +G G + Sbjct: 1041 PGLPGIHGLQGDKGEPGYSEGTRPGPPGPTGDPGLPGDMGKKGEMGQPGPPGHLGPAGPE 1100 Query: 95 GDSGDIGPPGPNGEPG 110 G G G PG G+PG Sbjct: 1101 GAPGSPGSPGLPGKPG 1116 Score = 68.9 bits (167), Expect = 4e-12 Identities = 40/93 (43%), Positives = 49/93 (52%), Gaps = 3/93 (3%) Query: 23 GHPQPAGDDACSVQILVP-GLKGDAGEKGDKGAPGRPGRVGPTGEKGDMGDKGQKGSVGR 81 G P PAG+ + + P G +G+ G +G KG G PG G G KG MGD G +G G Sbjct: 1161 GIPGPAGEKGETGLLRAPPGPRGNPGAQGAKGDRGAPGFPGLPGRKGAMGDAGPRGPTGI 1220 Query: 82 HGKIGPIGSKGE--KGDSGDIGPPGPNGEPGLP 112 G GP G G G +G+ GPPG G PG P Sbjct: 1221 EGFPGPPGLPGAIIPGQTGNRGPPGSRGSPGAP 1253 Score = 68.9 bits (167), Expect = 4e-12 Identities = 39/91 (42%), Positives = 46/91 (50%), Gaps = 4/91 (4%) Query: 23 GHPQPAGDDACSVQILVPGLKGDAGEKGDKGAPGRPGRVGPTGEKGDMGDKGQKGSVGRH 82 G P P GD PG+KG+ G G G+ G PG +GP G G GD G + Sbjct: 1301 GLPGPRGDPGFQG---FPGVKGEKGNPGFLGSIGPPGPIGPKGPPGVRGDPGTLKIISLP 1357 Query: 83 GKIGPIGSKGEKGDSGDIGPPGPNGEPGLPC 113 G GP G+ GE G G+ GPPGP G G PC Sbjct: 1358 GSPGPPGTPGEPGMQGEPGPPGPPGNLG-PC 1387 Score = 68.6 bits (166), Expect = 6e-12 Identities = 37/88 (42%), Positives = 47/88 (53%), Gaps = 5/88 (5%) Query: 23 GHPQPAGDDACSVQILVPGLKGDAGEKGDKGAPGRPGRVGPTGEKGDMGDKGQKGSVGRH 82 G P P G ++PG G+ G G +G+PG PG GP G +G KG KGS+G Sbjct: 1222 GFPGPPGLPGA----IIPGQTGNRGPPGSRGSPGAPGPPGPPGSH-VIGIKGDKGSMGHP 1276 Query: 83 GKIGPIGSKGEKGDSGDIGPPGPNGEPG 110 G GP G+ G+ G G +G PG G PG Sbjct: 1277 GPKGPPGTAGDMGPPGRLGAPGTPGLPG 1304 Score = 68.2 bits (165), Expect = 7e-12 Identities = 39/88 (44%), Positives = 46/88 (52%), Gaps = 15/88 (17%) Query: 40 PGLKGDAG---EKGDKGAPGRPGR---------VGPTGEKGDMGDKGQKGSVGRHG---K 84 PGLKG AG EKG++G PG PG GP G +GD+G G G G G Sbjct: 957 PGLKGFAGNPGEKGNRGVPGMPGLKGLKGLPGPAGPPGPRGDLGSTGNPGEPGLRGIPGS 1016 Query: 85 IGPIGSKGEKGDSGDIGPPGPNGEPGLP 112 +G +G G KG G +G PG G PGLP Sbjct: 1017 MGNMGMPGSKGKRGTLGFPGRAGRPGLP 1044 Score = 67.8 bits (164), Expect = 1e-11 Identities = 37/81 (45%), Positives = 44/81 (54%), Gaps = 9/81 (11%) Query: 40 PGLKGDAGEKGDKGAPGRPGRVGPTGEKGDMGDKGQKGSVGRHGKIGPIGSKGEKGDSGD 99 PG+ G GE G G G PG +GP G G+ G GQ+GS G G G G+ G KG+ GD Sbjct: 879 PGILGPPGEDGVIGMMGFPGAIGPPGPPGNPGTPGQRGSPGIPGVKGQRGTPGAKGEQGD 938 Query: 100 IGPPGPN---------GEPGL 111 G PGP+ GEPGL Sbjct: 939 KGNPGPSEISHVIGDKGEPGL 959 Score = 67.4 bits (163), Expect = 1e-11 Identities = 40/98 (40%), Positives = 48/98 (48%), Gaps = 5/98 (5%) Query: 23 GHPQPAGDDACSVQILVPGLKGDAGEKGDKGAP-----GRPGRVGPTGEKGDMGDKGQKG 77 G P G C ++ PGL G G G KG P G PG G GE+G+ G+ G+ G Sbjct: 712 GFPGTKGSLGCPGKMGEPGLPGKPGLPGAKGEPAVAMPGGPGTPGFPGERGNSGEHGEIG 771 Query: 78 SVGRHGKIGPIGSKGEKGDSGDIGPPGPNGEPGLPCEC 115 G G G G++G G GD G PGP GE G P C Sbjct: 772 LPGLPGLPGTPGNEGLDGPRGDPGQPGPPGEQGPPGRC 809 Score = 66.2 bits (160), Expect = 3e-11 Identities = 42/97 (43%), Positives = 47/97 (48%), Gaps = 7/97 (7%) Query: 21 PSGHPQPAGDDACSVQILVPGL------KGDAGEKGDKGAPGRPGRVGPTGEKGDMGDKG 74 P GH PAG + PGL GD G KG KG G PG GP G G G G Sbjct: 1090 PPGHLGPAGPEGAPGSPGSPGLPGKPGPHGDLGFKGIKGLLGPPGIRGPPGLPGFPGSPG 1149 Query: 75 QKGSVGRHGKIGPIGSKGEKGDSGDI-GPPGPNGEPG 110 G G G+ G G GEKG++G + PPGP G PG Sbjct: 1150 PMGIRGDQGRDGIPGPAGEKGETGLLRAPPGPRGNPG 1186 Score = 66.2 bits (160), Expect = 3e-11 Identities = 41/87 (47%), Positives = 45/87 (51%), Gaps = 14/87 (16%) Query: 40 PGLKGD--AGEKGDKGAPGRPGRVGPTGEKGDMGDKGQKGSVGRHGKIGPIGS------- 90 PG G G KGDKG+ G PG GP G GDMG G+ G+ G G GP G Sbjct: 1256 PGPPGSHVIGIKGDKGSMGHPGPKGPPGTAGDMGPPGRLGAPGTPGLPGPRGDPGFQGFP 1315 Query: 91 --KGEKGDS---GDIGPPGPNGEPGLP 112 KGEKG+ G IGPPGP G G P Sbjct: 1316 GVKGEKGNPGFLGSIGPPGPIGPKGPP 1342 Score = 65.5 bits (158), Expect = 5e-11 Identities = 38/101 (37%), Positives = 48/101 (47%), Gaps = 9/101 (8%) Query: 21 PSGHPQPAGDDACSVQILVPGL--KGDAGEKGDKGAPGRPGRVGPTGEKGDM-------G 71 P G P G + PG +G+ G +G +G PG PG G G +G++ G Sbjct: 597 PPGDPGSPGSPGPAGPAGPPGYGPQGEPGLQGTQGVPGAPGPPGEAGPRGELSVSTPVPG 656 Query: 72 DKGQKGSVGRHGKIGPIGSKGEKGDSGDIGPPGPNGEPGLP 112 G G G G GP G G G GD G PGP+GEPG+P Sbjct: 657 PPGPPGPPGHPGPQGPPGIPGSLGKCGDPGLPGPDGEPGIP 697 Score = 65.5 bits (158), Expect = 5e-11 Identities = 43/107 (40%), Positives = 48/107 (44%), Gaps = 22/107 (20%) Query: 21 PSGHPQPAGDDACSVQILVPGLKGDAGEKGDKGAPGRPGRVG--------PTGEKGDMGD 72 P GHP P G PG+ G G+ GD G PG G G P G KGD G Sbjct: 663 PPGHPGPQGP---------PGIPGSLGKCGDPGLPGPDGEPGIPGIGFPGPPGPKGDQGF 713 Query: 73 KGQKGSVGRHGKIGPIGSKGEKGDSGDIGP-----PGPNGEPGLPCE 114 G KGS+G GK+G G G+ G G G PG G PG P E Sbjct: 714 PGTKGSLGCPGKMGEPGLPGKPGLPGAKGEPAVAMPGGPGTPGFPGE 760 Score = 64.7 bits (156), Expect = 8e-11 Identities = 34/81 (41%), Positives = 41/81 (50%), Gaps = 9/81 (11%) Query: 39 VPGLKGDAGEKGDKGAPGRPGRVGPTGEKGDMGDKGQKGSV---------GRHGKIGPIG 89 VPG G G KG++G PG G G G+KGD+G G +G G G GP G Sbjct: 304 VPGFPGSEGVKGNRGFPGLMGEDGIKGQKGDIGPPGFRGPTEYYDTYQEKGDEGTPGPPG 363 Query: 90 SKGEKGDSGDIGPPGPNGEPG 110 +G +G G GPPG G PG Sbjct: 364 PRGARGPQGPSGPPGVPGSPG 384 Score = 64.7 bits (156), Expect = 8e-11 Identities = 36/91 (39%), Positives = 45/91 (49%), Gaps = 17/91 (18%) Query: 39 VPGLKGDAGEKGDKGAPGRPGRVGPTGEKGDMGDKGQKGSVGRHGKIGPIGSKGE----- 93 +PG G G +GD G+ G PG G G G MG+ G GS G+ G +G G G Sbjct: 986 LPGPAGPPGPRGDLGSTGNPGEPGLRGIPGSMGNMGMPGSKGKRGTLGFPGRAGRPGLPG 1045 Query: 94 ----KGDSGD--------IGPPGPNGEPGLP 112 +GD G+ GPPGP G+PGLP Sbjct: 1046 IHGLQGDKGEPGYSEGTRPGPPGPTGDPGLP 1076 Score = 64.3 bits (155), Expect = 1e-10 Identities = 36/85 (42%), Positives = 41/85 (48%), Gaps = 12/85 (14%) Query: 40 PGLKGDAGEKG------------DKGAPGRPGRVGPTGEKGDMGDKGQKGSVGRHGKIGP 87 PG KG+ G+KG DKG PG G G GEKG+ G G G G G GP Sbjct: 930 PGAKGEQGDKGNPGPSEISHVIGDKGEPGLKGFAGNPGEKGNRGVPGMPGLKGLKGLPGP 989 Query: 88 IGSKGEKGDSGDIGPPGPNGEPGLP 112 G G +GD G G PG G G+P Sbjct: 990 AGPPGPRGDLGSTGNPGEPGLRGIP 1014 Score = 63.5 bits (153), Expect = 2e-10 Identities = 39/99 (39%), Positives = 48/99 (48%), Gaps = 11/99 (11%) Query: 23 GHPQPAG--DDACSVQILVPGLKGDAGEKGDKGAPGRPGRVGPTGEKGDMGDKGQKGSVG 80 G P P+G ++ + PG G G+ G G PG PG G G +G G G+ G G Sbjct: 271 GPPGPSGLPGESYGSEKGAPGDPGLQGKPGKDGVPGFPGSEGVKGNRGFPGLMGEDGIKG 330 Query: 81 RHGKIGPIGSKG---------EKGDSGDIGPPGPNGEPG 110 + G IGP G +G EKGD G GPPGP G G Sbjct: 331 QKGDIGPPGFRGPTEYYDTYQEKGDEGTPGPPGPRGARG 369 Score = 63.5 bits (153), Expect = 2e-10 Identities = 37/92 (40%), Positives = 42/92 (45%), Gaps = 6/92 (6%) Query: 27 PAGDDACSVQILVPGLKGDAGEKGDKGAPGRPGRVGPTGEKGDMGDKGQKGSVGRHGKIG 86 P G+D + PG G G G+ G PG+ G G G KG G G KG G G G Sbjct: 884 PPGEDGVIGMMGFPGAIGPPGPPGNPGTPGQRGSPGIPGVKGQRGTPGAKGEQGDKGNPG 943 Query: 87 P------IGSKGEKGDSGDIGPPGPNGEPGLP 112 P IG KGE G G G PG G G+P Sbjct: 944 PSEISHVIGDKGEPGLKGFAGNPGEKGNRGVP 975 Score = 63.2 bits (152), Expect = 2e-10 Identities = 40/98 (40%), Positives = 44/98 (44%), Gaps = 5/98 (5%) Query: 18 SLLPSGHPQPAGDDACSVQILVPGLKGDAGEKGDKGAPGRPGRVGPTGEKGDMGDKGQKG 77 +L P G GD Q GL G G G KG PG G + +GEKGD G G G Sbjct: 543 TLQPEGQVGVPGDPGLRGQPGRKGLDGIPGTPGVKGLPGPKGELALSGEKGDQGPPGDPG 602 Query: 78 SVGRHGKIGP-----IGSKGEKGDSGDIGPPGPNGEPG 110 S G G GP G +GE G G G PG G PG Sbjct: 603 SPGSPGPAGPAGPPGYGPQGEPGLQGTQGVPGAPGPPG 640 Score = 63.2 bits (152), Expect = 2e-10 Identities = 41/103 (39%), Positives = 47/103 (45%), Gaps = 11/103 (10%) Query: 21 PSGHPQ--PAGDDACSVQILVPGLKGDAGEKGDKG-------APGRPGRVGPTGEKGDMG 71 P+G P P G+ VPG G GE G +G PG PG GP G G G Sbjct: 612 PAGPPGYGPQGEPGLQGTQGVPGAPGPPGEAGPRGELSVSTPVPGPPGPPGPPGHPGPQG 671 Query: 72 DKGQKGSVGRHGKIGPIGSKGEKG--DSGDIGPPGPNGEPGLP 112 G GS+G+ G G G GE G G GPPGP G+ G P Sbjct: 672 PPGIPGSLGKCGDPGLPGPDGEPGIPGIGFPGPPGPKGDQGFP 714 Score = 63.2 bits (152), Expect = 2e-10 Identities = 38/92 (41%), Positives = 44/92 (47%), Gaps = 14/92 (15%) Query: 23 GHPQPAGDDACSVQILVPGL--KGDAGEKGDKGAPGRPGRVGPTGEKGDMGDKGQKGSVG 80 G P GD +PGL G GE G G PG G +GP G++G G+ G G G Sbjct: 833 GKTGPKGDPG------IPGLDRSGFPGETGSPGIPGHQGEMGPLGQRGYPGNPGILGPPG 886 Query: 81 RHGKIGPIGSKGEKGDSGDIGPPGPNGEPGLP 112 G IG +G G IGPPGP G PG P Sbjct: 887 EDGVIGMMGFPGA------IGPPGPPGNPGTP 912 Score = 63.2 bits (152), Expect = 2e-10 Identities = 38/95 (40%), Positives = 47/95 (49%), Gaps = 3/95 (3%) Query: 21 PSGHPQPAGDDACSVQILVPGLKGD---AGEKGDKGAPGRPGRVGPTGEKGDMGDKGQKG 77 P+G P GD ++ PG G AG +G G+PG PG G G GD+G KG KG Sbjct: 1069 PTGDPGLPGDMGKKGEMGQPGPPGHLGPAGPEGAPGSPGSPGLPGKPGPHGDLGFKGIKG 1128 Query: 78 SVGRHGKIGPIGSKGEKGDSGDIGPPGPNGEPGLP 112 +G G GP G G G G +G G G G+P Sbjct: 1129 LLGPPGIRGPPGLPGFPGSPGPMGIRGDQGRDGIP 1163 Score = 61.2 bits (147), Expect = 9e-10 Identities = 37/88 (42%), Positives = 42/88 (47%), Gaps = 4/88 (4%) Query: 27 PAGDDACSV----QILVPGLKGDAGEKGDKGAPGRPGRVGPTGEKGDMGDKGQKGSVGRH 82 PA C Q G KG+ GEKG G PG PG+ G TG +G G +G KG G Sbjct: 25 PAASKGCVCKDKGQCFCDGAKGEKGEKGFPGPPGSPGQKGFTGPEGLPGPQGPKGFPGLP 84 Query: 83 GKIGPIGSKGEKGDSGDIGPPGPNGEPG 110 G G G +G G G G PG G PG Sbjct: 85 GLTGSKGVRGISGLPGFSGSPGLPGTPG 112 Score = 60.8 bits (146), Expect = 1e-09 Identities = 35/80 (43%), Positives = 43/80 (53%), Gaps = 7/80 (8%) Query: 40 PGLKGDAGEKGDKGAPGRP-GRVGPTGEKGDMGDKGQKG------SVGRHGKIGPIGSKG 92 PG +GD G KG+KG +P G+VG G+ G G G+KG + G G GP G Sbjct: 528 PGAQGDPGLKGEKGETLQPEGQVGVPGDPGLRGQPGRKGLDGIPGTPGVKGLPGPKGELA 587 Query: 93 EKGDSGDIGPPGPNGEPGLP 112 G+ GD GPPG G PG P Sbjct: 588 LSGEKGDQGPPGDPGSPGSP 607 Score = 60.8 bits (146), Expect = 1e-09 Identities = 41/111 (36%), Positives = 49/111 (44%), Gaps = 24/111 (21%) Query: 23 GHPQPAGDDACSVQILVPGLKGDAGEKGDKGAPGRPGRVGPTGEKG--DMGDKGQKGSVG 80 G P P G+ A S G KGD G GD G+PG PG GP G G G+ G +G+ G Sbjct: 578 GLPGPKGELALS------GEKGDQGPPGDPGSPGSPGPAGPAGPPGYGPQGEPGLQGTQG 631 Query: 81 RHGKIGPIGSKGEKGD----------------SGDIGPPGPNGEPGLPCEC 115 G GP G G +G+ G GP GP G PG +C Sbjct: 632 VPGAPGPPGEAGPRGELSVSTPVPGPPGPPGPPGHPGPQGPPGIPGSLGKC 682 Score = 60.8 bits (146), Expect = 1e-09 Identities = 42/112 (37%), Positives = 51/112 (45%), Gaps = 10/112 (8%) Query: 9 GVLISLAFLSLL-PSGHPQPAGDDACSVQILVPGLKGDAGEKGDKGAPGRPGRVGPT--- 64 GV+ + F + P G P G +PG+KG G G KG G G GP+ Sbjct: 889 GVIGMMGFPGAIGPPGPPGNPGTPGQRGSPGIPGVKGQRGTPGAKGEQGDKGNPGPSEIS 948 Query: 65 ---GEKGDMGDK---GQKGSVGRHGKIGPIGSKGEKGDSGDIGPPGPNGEPG 110 G+KG+ G K G G G G G G KG KG G GPPGP G+ G Sbjct: 949 HVIGDKGEPGLKGFAGNPGEKGNRGVPGMPGLKGLKGLPGPAGPPGPRGDLG 1000 Score = 60.8 bits (146), Expect = 1e-09 Identities = 32/77 (41%), Positives = 39/77 (50%), Gaps = 6/77 (7%) Query: 40 PGLKGDAGEKGDKGAPGR------PGRVGPTGEKGDMGDKGQKGSVGRHGKIGPIGSKGE 93 PG G G G +G PG PG GP G G+ G +G+ G G G +GP G +G+ Sbjct: 1333 PGPIGPKGPPGVRGDPGTLKIISLPGSPGPPGTPGEPGMQGEPGPPGPPGNLGPCGPRGK 1392 Query: 94 KGDSGDIGPPGPNGEPG 110 G G G PGP GE G Sbjct: 1393 PGKDGKPGTPGPAGEKG 1409 Score = 60.1 bits (144), Expect = 2e-09 Identities = 44/110 (40%), Positives = 52/110 (47%), Gaps = 26/110 (23%) Query: 22 SGHPQPAGDDACSVQILVPGLKGDA-GEKGDKGAPGRPGRVGPTG--------EKGDMGD 72 +G P P G V + P + D GEKGDKGA G PG GP+G EKG GD Sbjct: 235 TGPPGPPG--TVIVTLTGPDNRTDLKGEKGDKGAMGEPGPPGPSGLPGESYGSEKGAPGD 292 Query: 73 KGQKGSVGRHGKIGPIGSKGEKGD---------------SGDIGPPGPNG 107 G +G G+ G G GS+G KG+ GDIGPPG G Sbjct: 293 PGLQGKPGKDGVPGFPGSEGVKGNRGFPGLMGEDGIKGQKGDIGPPGFRG 342 Score = 60.1 bits (144), Expect = 2e-09 Identities = 31/73 (42%), Positives = 38/73 (52%) Query: 40 PGLKGDAGEKGDKGAPGRPGRVGPTGEKGDMGDKGQKGSVGRHGKIGPIGSKGEKGDSGD 99 PG G G++G G PG G+ G G KG+ GDKG G IG G G KG +G+ Sbjct: 906 PGNPGTPGQRGSPGIPGVKGQRGTPGAKGEQGDKGNPGPSEISHVIGDKGEPGLKGFAGN 965 Query: 100 IGPPGPNGEPGLP 112 G G G PG+P Sbjct: 966 PGEKGNRGVPGMP 978 Score = 58.5 bits (140), Expect = 6e-09 Identities = 34/74 (45%), Positives = 38/74 (51%), Gaps = 3/74 (4%) Query: 41 GLKGDAGEKGDKGAPGRPGRV--GPTGEKGDMGDKGQKGSVGRHGKIGPIGSKGEKGDSG 98 G +GD G+ G G G PGR GP G +G G G KG GR GK GP G G G Sbjct: 789 GPRGDPGQPGPPGEQGPPGRCIEGPRGAQGLPGLNGLKGQQGRRGKTGPKGDPGIPGLDR 848 Query: 99 DIGPPGPNGEPGLP 112 G PG G PG+P Sbjct: 849 S-GFPGETGSPGIP 861 Score = 58.5 bits (140), Expect = 6e-09 Identities = 34/87 (39%), Positives = 46/87 (52%), Gaps = 1/87 (1%) Query: 13 SLAFLSLLPS-GHPQPAGDDACSVQILVPGLKGDAGEKGDKGAPGRPGRVGPTGEKGDMG 71 +L +SL S G P G+ + PG G+ G G +G PG+ G+ G G G+ G Sbjct: 1350 TLKIISLPGSPGPPGTPGEPGMQGEPGPPGPPGNLGPCGPRGKPGKDGKPGTPGPAGEKG 1409 Query: 72 DKGQKGSVGRHGKIGPIGSKGEKGDSG 98 +KG KG G G G G KG++GDSG Sbjct: 1410 NKGSKGEPGPAGSDGLPGLKGKRGDSG 1436 Score = 58.2 bits (139), Expect = 8e-09 Identities = 40/93 (43%), Positives = 44/93 (47%), Gaps = 21/93 (22%) Query: 40 PGLKGDAGEK----------GDKGAPGRPGR------VGPTGEKGDMGDKGQ---KGSVG 80 PGLKG+ GE GD G G+PGR G G KG G KG+ G G Sbjct: 534 PGLKGEKGETLQPEGQVGVPGDPGLRGQPGRKGLDGIPGTPGVKGLPGPKGELALSGEKG 593 Query: 81 RHGKIGPIGSKGEKGDSGDIGPP--GPNGEPGL 111 G G GS G G +G GPP GP GEPGL Sbjct: 594 DQGPPGDPGSPGSPGPAGPAGPPGYGPQGEPGL 626 Score = 57.4 bits (137), Expect = 1e-08 Identities = 34/69 (49%), Positives = 38/69 (55%), Gaps = 3/69 (4%) Query: 44 GDAGEKGDKGAPGRPGRVGPTGEKGDMGDKGQKGSVGRHGKIGPIGSKGEKGDSGDIGPP 103 G GEKG+KG PG PG G G G G G +G G G G GSKG +G S G P Sbjct: 43 GAKGEKGEKGFPGPPGSPGQKGFTGPEGLPGPQGPKGFPGLPGLTGSKGVRGIS---GLP 99 Query: 104 GPNGEPGLP 112 G +G PGLP Sbjct: 100 GFSGSPGLP 108 Score = 56.6 bits (135), Expect = 2e-08 Identities = 34/77 (44%), Positives = 38/77 (49%), Gaps = 4/77 (5%) Query: 40 PGLKGDAGEKGDKGAPGRPGRVGPTGEKGDMGDKGQKGSVGRHGKIGPIGSKGEKGDS-- 97 PGL G G G KG PGR G G G G G+ G G G G G G KGEKG++ Sbjct: 486 PGLPGLPGLHGVKGIPGRQGAAGLKGSPGSPGNTGLPGFPGFPGAQGDPGLKGEKGETLQ 545 Query: 98 --GDIGPPGPNGEPGLP 112 G +G PG G G P Sbjct: 546 PEGQVGVPGDPGLRGQP 562 Score = 56.2 bits (134), Expect = 3e-08 Identities = 35/92 (38%), Positives = 41/92 (44%), Gaps = 12/92 (13%) Query: 21 PSGHPQPAGDDACSVQILVPGLKGDAGEKGDKGAPGRPGRVGPTGEKGDMGDKGQKGSVG 80 P G P P G PGL G G KG +G G P G G G G G+ G Sbjct: 68 PEGLPGPQGPKG------FPGLPGLTGSKGVRGISGLP------GFSGSPGLPGTPGNTG 115 Query: 81 RHGKIGPIGSKGEKGDSGDIGPPGPNGEPGLP 112 +G +G G G KG+ G G PG G PG+P Sbjct: 116 PYGLVGVPGCSGSKGEQGFPGLPGTLGYPGIP 147 Score = 55.8 bits (133), Expect = 4e-08 Identities = 40/117 (34%), Positives = 50/117 (42%), Gaps = 37/117 (31%) Query: 35 VQILVPGLKGDAGEKGDKGAPGRPGR------------------VGPTGEKGDMGD---- 72 +++ G G G G +G PG PG +GP G KG MG+ Sbjct: 165 IELDAKGDPGLPGAPGPQGLPGPPGFPGPVGPPGPPGFFGFPGAMGPRGPKGHMGERVIG 224 Query: 73 -KGQKGSVGRHGKIGPIGS--------------KGEKGDSGDIGPPGPNGEPGLPCE 114 KG++G G G GP G+ KGEKGD G +G PGP G GLP E Sbjct: 225 HKGERGVKGLTGPPGPPGTVIVTLTGPDNRTDLKGEKGDKGAMGEPGPPGPSGLPGE 281 Score = 55.1 bits (131), Expect = 6e-08 Identities = 46/120 (38%), Positives = 50/120 (41%), Gaps = 28/120 (23%) Query: 21 PSGHPQPAGDDACSVQILV-----PGLKGDAGEKGDKG--------------APGRPGRV 61 PSG P G S L PGLKG GE+G G +PG PG Sbjct: 373 PSGPPGVPGSPGSSRPGLRGAPGWPGLKGSKGERGRPGKDAMGTPGSPGCAGSPGLPGSP 432 Query: 62 GPTGEKGDM-------GDKGQKGSVGRHGKIGPIGSKGEKGDSGDIGP--PGPNGEPGLP 112 GP G GD+ GD G G +G G G G KGE G P PGP G PGLP Sbjct: 433 GPPGPPGDIVFRKGPPGDHGLPGYLGSPGIPGVDGPKGEPGLLCTQCPYIPGPPGLPGLP 492 Score = 54.3 bits (129), Expect = 1e-07 Identities = 37/99 (37%), Positives = 41/99 (41%), Gaps = 31/99 (31%) Query: 40 PGLKGDAGEKGDKGAP--------------------GRPGRVGPTGEKGDMGDKGQKGSV 79 PG+ G AG KG KGAP G G GP G G +G G G Sbjct: 144 PGIPGAAGLKGQKGAPAKEEDIELDAKGDPGLPGAPGPQGLPGPPGFPGPVGPPGPPGFF 203 Query: 80 GRHGKIGP-----------IGSKGEKGDSGDIGPPGPNG 107 G G +GP IG KGE+G G GPPGP G Sbjct: 204 GFPGAMGPRGPKGHMGERVIGHKGERGVKGLTGPPGPPG 242 Score = 52.8 bits (125), Expect = 3e-07 Identities = 35/84 (41%), Positives = 40/84 (47%), Gaps = 10/84 (11%) Query: 41 GLKGDAGEKGDKGAPGRPGRVGPTGEKGDMGDKGQ----KGSVGRHGKIGPIGSKGEKGD 96 GLKG G G+ G PG PG G G+ G G+KG+ +G VG G G G G KG Sbjct: 508 GLKGSPGSPGNTGLPGFPGFPGAQGDPGLKGEKGETLQPEGQVGVPGDPGLRGQPGRKGL 567 Query: 97 SGDIGPPG------PNGEPGLPCE 114 G G PG P GE L E Sbjct: 568 DGIPGTPGVKGLPGPKGELALSGE 591 Score = 52.4 bits (124), Expect = 4e-07 Identities = 32/71 (45%), Positives = 34/71 (47%) Query: 40 PGLKGDAGEKGDKGAPGRPGRVGPTGEKGDMGDKGQKGSVGRHGKIGPIGSKGEKGDSGD 99 PG G G+KG G G PG GP G G G G KG G G G GS G G G+ Sbjct: 54 PGPPGSPGQKGFTGPEGLPGPQGPKGFPGLPGLTGSKGVRGISGLPGFSGSPGLPGTPGN 113 Query: 100 IGPPGPNGEPG 110 GP G G PG Sbjct: 114 TGPYGLVGVPG 124 Score = 51.2 bits (121), Expect = 9e-07 Identities = 42/123 (34%), Positives = 52/123 (42%), Gaps = 25/123 (20%) Query: 23 GHPQPAGDDACSVQILVPGLKGDAGEKGDKGAPGRPGRVGPTGEKGDM------------ 70 G P P GD + G GD G G G+PG PG GP GE G + Sbjct: 433 GPPGPPGDI-----VFRKGPPGDHGLPGYLGSPGIPGVDGPKGEPGLLCTQCPYIPGPPG 487 Query: 71 -----GDKGQKGSVGRHGKIGPIGSKGEKGDSG---DIGPPGPNGEPGLPCECSQLRKAI 122 G G KG GR G G GS G G++G G PG G+PGL E + + Sbjct: 488 LPGLPGLHGVKGIPGRQGAAGLKGSPGSPGNTGLPGFPGFPGAQGDPGLKGEKGETLQPE 547 Query: 123 GEM 125 G++ Sbjct: 548 GQV 550 Score = 50.1 bits (118), Expect = 2e-06 Identities = 32/81 (39%), Positives = 37/81 (45%), Gaps = 1/81 (1%) Query: 33 CSVQILVPGLKGDAGEKGDKGAPGRPGRVGPTGEKGDMGDKGQKGSVGRHGKIGPIGSKG 92 C+ +PG G G G G G PGR G G KG G G G G G G G G Sbjct: 476 CTQCPYIPGPPGLPGLPGLHGVKGIPGRQGAAGLKGSPGSPGNTGLPGFPGFPGAQGDPG 535 Query: 93 EKGDSGD-IGPPGPNGEPGLP 112 KG+ G+ + P G G PG P Sbjct: 536 LKGEKGETLQPEGQVGVPGDP 556 Score = 48.5 bits (114), Expect = 6e-06 Identities = 35/82 (42%), Positives = 37/82 (45%), Gaps = 13/82 (15%) Query: 40 PGLKGD---AGEKGDKGAPGRPGRVGPT------GEKGDMGDKGQKGSVGRHGKIGPIGS 90 PGL G+ G+KGD G PG GPT EKGD G G G G G GP G Sbjct: 320 PGLMGEDGIKGQKGDIGPPGFR---GPTEYYDTYQEKGDEGTPGPPGPRGARGPQGPSGP 376 Query: 91 KGEKGDSGDIGPPGPNGEPGLP 112 G G G PG G PG P Sbjct: 377 PGVPGSPGS-SRPGLRGAPGWP 397 Score = 43.9 bits (102), Expect = 1e-04 Identities = 22/47 (46%), Positives = 25/47 (53%) Query: 66 EKGDMGDKGQKGSVGRHGKIGPIGSKGEKGDSGDIGPPGPNGEPGLP 112 +KG G KG G G GP GS G+KG +G G PGP G G P Sbjct: 35 DKGQCFCDGAKGEKGEKGFPGPPGSPGQKGFTGPEGLPGPQGPKGFP 81 Score = 33.1 bits (74), Expect = 0.26 Identities = 24/69 (34%), Positives = 29/69 (42%), Gaps = 10/69 (14%) Query: 23 GHPQPAGDDACSVQILVPGLKGDAGEKGDKGAPGRPGRVGPTGEKGDMGDKGQKGSV-GR 81 G P PAG+ G KG GE G G+ G PG G G+ G +G V R Sbjct: 1400 GTPGPAGEK---------GNKGSKGEPGPAGSDGLPGLKGKRGDSGSPATWTTRGFVFTR 1450 Query: 82 HGKIGPIGS 90 H + I S Sbjct: 1451 HSQTTAIPS 1459 >gi|89142733 alpha 3 type IV collagen isoform 2 precursor [Homo sapiens] Length = 1637 Score = 80.1 bits (196), Expect = 2e-15 Identities = 44/90 (48%), Positives = 49/90 (54%), Gaps = 12/90 (13%) Query: 23 GHPQPAGDDACSVQILVPGLKGDAGEKGDKGAPGRPGRVGPTGEKGDMGDKGQKGSVGRH 82 G P P GD PGL GD G+KG+ G PG PG +GP G + G G GS G Sbjct: 1065 GPPGPTGD---------PGLPGDMGKKGEMGQPGPPGHLGPAGPE---GAPGSPGSPGLP 1112 Query: 83 GKIGPIGSKGEKGDSGDIGPPGPNGEPGLP 112 GK GP G G KG G +GPPG G PGLP Sbjct: 1113 GKPGPHGDLGFKGIKGLLGPPGIRGPPGLP 1142 Score = 77.8 bits (190), Expect = 9e-15 Identities = 39/91 (42%), Positives = 46/91 (50%) Query: 21 PSGHPQPAGDDACSVQILVPGLKGDAGEKGDKGAPGRPGRVGPTGEKGDMGDKGQKGSVG 80 P G P GD I +PG G G G+ G G PG GP G G G +G+ G G Sbjct: 1338 PKGPPGVRGDPGTLKIISLPGSPGPPGTPGEPGMQGEPGPPGPPGNLGPCGPRGKPGKDG 1397 Query: 81 RHGKIGPIGSKGEKGDSGDIGPPGPNGEPGL 111 + G GP G KG KG G+ GP G +G PGL Sbjct: 1398 KPGTPGPAGEKGNKGSKGEPGPAGSDGLPGL 1428 Score = 73.9 bits (180), Expect = 1e-13 Identities = 45/110 (40%), Positives = 52/110 (47%), Gaps = 27/110 (24%) Query: 23 GHPQPAGDDACSVQILVPGLKGDAGEKGDKGAPGRPGRVGPTGE---------KGDMGDK 73 GHP P G PG GD G G GAPG PG GP G+ KG+ G+ Sbjct: 1274 GHPGPKGP---------PGTAGDMGPPGRLGAPGTPGLPGPRGDPGFQGFPGVKGEKGNP 1324 Query: 74 GQKGSVGRHGKIGPIGSKGEKGDSGDI---------GPPGPNGEPGLPCE 114 G GS+G G IGP G G +GD G + GPPG GEPG+ E Sbjct: 1325 GFLGSIGPPGPIGPKGPPGVRGDPGTLKIISLPGSPGPPGTPGEPGMQGE 1374 Score = 70.5 bits (171), Expect = 1e-12 Identities = 37/76 (48%), Positives = 45/76 (59%), Gaps = 5/76 (6%) Query: 40 PGLKGDAGEKGDKGAPG-----RPGRVGPTGEKGDMGDKGQKGSVGRHGKIGPIGSKGEK 94 PGL G G +GDKG PG RPG GPTG+ G GD G+KG +G+ G G +G G + Sbjct: 1041 PGLPGIHGLQGDKGEPGYSEGTRPGPPGPTGDPGLPGDMGKKGEMGQPGPPGHLGPAGPE 1100 Query: 95 GDSGDIGPPGPNGEPG 110 G G G PG G+PG Sbjct: 1101 GAPGSPGSPGLPGKPG 1116 Score = 68.9 bits (167), Expect = 4e-12 Identities = 40/93 (43%), Positives = 49/93 (52%), Gaps = 3/93 (3%) Query: 23 GHPQPAGDDACSVQILVP-GLKGDAGEKGDKGAPGRPGRVGPTGEKGDMGDKGQKGSVGR 81 G P PAG+ + + P G +G+ G +G KG G PG G G KG MGD G +G G Sbjct: 1161 GIPGPAGEKGETGLLRAPPGPRGNPGAQGAKGDRGAPGFPGLPGRKGAMGDAGPRGPTGI 1220 Query: 82 HGKIGPIGSKGE--KGDSGDIGPPGPNGEPGLP 112 G GP G G G +G+ GPPG G PG P Sbjct: 1221 EGFPGPPGLPGAIIPGQTGNRGPPGSRGSPGAP 1253 Score = 68.9 bits (167), Expect = 4e-12 Identities = 39/91 (42%), Positives = 46/91 (50%), Gaps = 4/91 (4%) Query: 23 GHPQPAGDDACSVQILVPGLKGDAGEKGDKGAPGRPGRVGPTGEKGDMGDKGQKGSVGRH 82 G P P GD PG+KG+ G G G+ G PG +GP G G GD G + Sbjct: 1301 GLPGPRGDPGFQG---FPGVKGEKGNPGFLGSIGPPGPIGPKGPPGVRGDPGTLKIISLP 1357 Query: 83 GKIGPIGSKGEKGDSGDIGPPGPNGEPGLPC 113 G GP G+ GE G G+ GPPGP G G PC Sbjct: 1358 GSPGPPGTPGEPGMQGEPGPPGPPGNLG-PC 1387 Score = 68.6 bits (166), Expect = 6e-12 Identities = 37/88 (42%), Positives = 47/88 (53%), Gaps = 5/88 (5%) Query: 23 GHPQPAGDDACSVQILVPGLKGDAGEKGDKGAPGRPGRVGPTGEKGDMGDKGQKGSVGRH 82 G P P G ++PG G+ G G +G+PG PG GP G +G KG KGS+G Sbjct: 1222 GFPGPPGLPGA----IIPGQTGNRGPPGSRGSPGAPGPPGPPGSH-VIGIKGDKGSMGHP 1276 Query: 83 GKIGPIGSKGEKGDSGDIGPPGPNGEPG 110 G GP G+ G+ G G +G PG G PG Sbjct: 1277 GPKGPPGTAGDMGPPGRLGAPGTPGLPG 1304 Score = 68.2 bits (165), Expect = 7e-12 Identities = 39/88 (44%), Positives = 46/88 (52%), Gaps = 15/88 (17%) Query: 40 PGLKGDAG---EKGDKGAPGRPGR---------VGPTGEKGDMGDKGQKGSVGRHG---K 84 PGLKG AG EKG++G PG PG GP G +GD+G G G G G Sbjct: 957 PGLKGFAGNPGEKGNRGVPGMPGLKGLKGLPGPAGPPGPRGDLGSTGNPGEPGLRGIPGS 1016 Query: 85 IGPIGSKGEKGDSGDIGPPGPNGEPGLP 112 +G +G G KG G +G PG G PGLP Sbjct: 1017 MGNMGMPGSKGKRGTLGFPGRAGRPGLP 1044 Score = 67.8 bits (164), Expect = 1e-11 Identities = 37/81 (45%), Positives = 44/81 (54%), Gaps = 9/81 (11%) Query: 40 PGLKGDAGEKGDKGAPGRPGRVGPTGEKGDMGDKGQKGSVGRHGKIGPIGSKGEKGDSGD 99 PG+ G GE G G G PG +GP G G+ G GQ+GS G G G G+ G KG+ GD Sbjct: 879 PGILGPPGEDGVIGMMGFPGAIGPPGPPGNPGTPGQRGSPGIPGVKGQRGTPGAKGEQGD 938 Query: 100 IGPPGPN---------GEPGL 111 G PGP+ GEPGL Sbjct: 939 KGNPGPSEISHVIGDKGEPGL 959 Score = 67.4 bits (163), Expect = 1e-11 Identities = 40/98 (40%), Positives = 48/98 (48%), Gaps = 5/98 (5%) Query: 23 GHPQPAGDDACSVQILVPGLKGDAGEKGDKGAP-----GRPGRVGPTGEKGDMGDKGQKG 77 G P G C ++ PGL G G G KG P G PG G GE+G+ G+ G+ G Sbjct: 712 GFPGTKGSLGCPGKMGEPGLPGKPGLPGAKGEPAVAMPGGPGTPGFPGERGNSGEHGEIG 771 Query: 78 SVGRHGKIGPIGSKGEKGDSGDIGPPGPNGEPGLPCEC 115 G G G G++G G GD G PGP GE G P C Sbjct: 772 LPGLPGLPGTPGNEGLDGPRGDPGQPGPPGEQGPPGRC 809 Score = 66.2 bits (160), Expect = 3e-11 Identities = 42/97 (43%), Positives = 47/97 (48%), Gaps = 7/97 (7%) Query: 21 PSGHPQPAGDDACSVQILVPGL------KGDAGEKGDKGAPGRPGRVGPTGEKGDMGDKG 74 P GH PAG + PGL GD G KG KG G PG GP G G G G Sbjct: 1090 PPGHLGPAGPEGAPGSPGSPGLPGKPGPHGDLGFKGIKGLLGPPGIRGPPGLPGFPGSPG 1149 Query: 75 QKGSVGRHGKIGPIGSKGEKGDSGDI-GPPGPNGEPG 110 G G G+ G G GEKG++G + PPGP G PG Sbjct: 1150 PMGIRGDQGRDGIPGPAGEKGETGLLRAPPGPRGNPG 1186 Score = 66.2 bits (160), Expect = 3e-11 Identities = 41/87 (47%), Positives = 45/87 (51%), Gaps = 14/87 (16%) Query: 40 PGLKGD--AGEKGDKGAPGRPGRVGPTGEKGDMGDKGQKGSVGRHGKIGPIGS------- 90 PG G G KGDKG+ G PG GP G GDMG G+ G+ G G GP G Sbjct: 1256 PGPPGSHVIGIKGDKGSMGHPGPKGPPGTAGDMGPPGRLGAPGTPGLPGPRGDPGFQGFP 1315 Query: 91 --KGEKGDS---GDIGPPGPNGEPGLP 112 KGEKG+ G IGPPGP G G P Sbjct: 1316 GVKGEKGNPGFLGSIGPPGPIGPKGPP 1342 Score = 65.5 bits (158), Expect = 5e-11 Identities = 38/101 (37%), Positives = 48/101 (47%), Gaps = 9/101 (8%) Query: 21 PSGHPQPAGDDACSVQILVPGL--KGDAGEKGDKGAPGRPGRVGPTGEKGDM-------G 71 P G P G + PG +G+ G +G +G PG PG G G +G++ G Sbjct: 597 PPGDPGSPGSPGPAGPAGPPGYGPQGEPGLQGTQGVPGAPGPPGEAGPRGELSVSTPVPG 656 Query: 72 DKGQKGSVGRHGKIGPIGSKGEKGDSGDIGPPGPNGEPGLP 112 G G G G GP G G G GD G PGP+GEPG+P Sbjct: 657 PPGPPGPPGHPGPQGPPGIPGSLGKCGDPGLPGPDGEPGIP 697 Score = 65.5 bits (158), Expect = 5e-11 Identities = 43/107 (40%), Positives = 48/107 (44%), Gaps = 22/107 (20%) Query: 21 PSGHPQPAGDDACSVQILVPGLKGDAGEKGDKGAPGRPGRVG--------PTGEKGDMGD 72 P GHP P G PG+ G G+ GD G PG G G P G KGD G Sbjct: 663 PPGHPGPQGP---------PGIPGSLGKCGDPGLPGPDGEPGIPGIGFPGPPGPKGDQGF 713 Query: 73 KGQKGSVGRHGKIGPIGSKGEKGDSGDIGP-----PGPNGEPGLPCE 114 G KGS+G GK+G G G+ G G G PG G PG P E Sbjct: 714 PGTKGSLGCPGKMGEPGLPGKPGLPGAKGEPAVAMPGGPGTPGFPGE 760 Score = 64.7 bits (156), Expect = 8e-11 Identities = 34/81 (41%), Positives = 41/81 (50%), Gaps = 9/81 (11%) Query: 39 VPGLKGDAGEKGDKGAPGRPGRVGPTGEKGDMGDKGQKGSV---------GRHGKIGPIG 89 VPG G G KG++G PG G G G+KGD+G G +G G G GP G Sbjct: 304 VPGFPGSEGVKGNRGFPGLMGEDGIKGQKGDIGPPGFRGPTEYYDTYQEKGDEGTPGPPG 363 Query: 90 SKGEKGDSGDIGPPGPNGEPG 110 +G +G G GPPG G PG Sbjct: 364 PRGARGPQGPSGPPGVPGSPG 384 Score = 64.7 bits (156), Expect = 8e-11 Identities = 36/91 (39%), Positives = 45/91 (49%), Gaps = 17/91 (18%) Query: 39 VPGLKGDAGEKGDKGAPGRPGRVGPTGEKGDMGDKGQKGSVGRHGKIGPIGSKGE----- 93 +PG G G +GD G+ G PG G G G MG+ G GS G+ G +G G G Sbjct: 986 LPGPAGPPGPRGDLGSTGNPGEPGLRGIPGSMGNMGMPGSKGKRGTLGFPGRAGRPGLPG 1045 Query: 94 ----KGDSGD--------IGPPGPNGEPGLP 112 +GD G+ GPPGP G+PGLP Sbjct: 1046 IHGLQGDKGEPGYSEGTRPGPPGPTGDPGLP 1076 Score = 64.3 bits (155), Expect = 1e-10 Identities = 36/85 (42%), Positives = 41/85 (48%), Gaps = 12/85 (14%) Query: 40 PGLKGDAGEKG------------DKGAPGRPGRVGPTGEKGDMGDKGQKGSVGRHGKIGP 87 PG KG+ G+KG DKG PG G G GEKG+ G G G G G GP Sbjct: 930 PGAKGEQGDKGNPGPSEISHVIGDKGEPGLKGFAGNPGEKGNRGVPGMPGLKGLKGLPGP 989 Query: 88 IGSKGEKGDSGDIGPPGPNGEPGLP 112 G G +GD G G PG G G+P Sbjct: 990 AGPPGPRGDLGSTGNPGEPGLRGIP 1014 Score = 63.5 bits (153), Expect = 2e-10 Identities = 39/99 (39%), Positives = 48/99 (48%), Gaps = 11/99 (11%) Query: 23 GHPQPAG--DDACSVQILVPGLKGDAGEKGDKGAPGRPGRVGPTGEKGDMGDKGQKGSVG 80 G P P+G ++ + PG G G+ G G PG PG G G +G G G+ G G Sbjct: 271 GPPGPSGLPGESYGSEKGAPGDPGLQGKPGKDGVPGFPGSEGVKGNRGFPGLMGEDGIKG 330 Query: 81 RHGKIGPIGSKG---------EKGDSGDIGPPGPNGEPG 110 + G IGP G +G EKGD G GPPGP G G Sbjct: 331 QKGDIGPPGFRGPTEYYDTYQEKGDEGTPGPPGPRGARG 369 Score = 63.5 bits (153), Expect = 2e-10 Identities = 37/92 (40%), Positives = 42/92 (45%), Gaps = 6/92 (6%) Query: 27 PAGDDACSVQILVPGLKGDAGEKGDKGAPGRPGRVGPTGEKGDMGDKGQKGSVGRHGKIG 86 P G+D + PG G G G+ G PG+ G G G KG G G KG G G G Sbjct: 884 PPGEDGVIGMMGFPGAIGPPGPPGNPGTPGQRGSPGIPGVKGQRGTPGAKGEQGDKGNPG 943 Query: 87 P------IGSKGEKGDSGDIGPPGPNGEPGLP 112 P IG KGE G G G PG G G+P Sbjct: 944 PSEISHVIGDKGEPGLKGFAGNPGEKGNRGVP 975 Score = 63.2 bits (152), Expect = 2e-10 Identities = 40/98 (40%), Positives = 44/98 (44%), Gaps = 5/98 (5%) Query: 18 SLLPSGHPQPAGDDACSVQILVPGLKGDAGEKGDKGAPGRPGRVGPTGEKGDMGDKGQKG 77 +L P G GD Q GL G G G KG PG G + +GEKGD G G G Sbjct: 543 TLQPEGQVGVPGDPGLRGQPGRKGLDGIPGTPGVKGLPGPKGELALSGEKGDQGPPGDPG 602 Query: 78 SVGRHGKIGP-----IGSKGEKGDSGDIGPPGPNGEPG 110 S G G GP G +GE G G G PG G PG Sbjct: 603 SPGSPGPAGPAGPPGYGPQGEPGLQGTQGVPGAPGPPG 640 Score = 63.2 bits (152), Expect = 2e-10 Identities = 41/103 (39%), Positives = 47/103 (45%), Gaps = 11/103 (10%) Query: 21 PSGHPQ--PAGDDACSVQILVPGLKGDAGEKGDKG-------APGRPGRVGPTGEKGDMG 71 P+G P P G+ VPG G GE G +G PG PG GP G G G Sbjct: 612 PAGPPGYGPQGEPGLQGTQGVPGAPGPPGEAGPRGELSVSTPVPGPPGPPGPPGHPGPQG 671 Query: 72 DKGQKGSVGRHGKIGPIGSKGEKG--DSGDIGPPGPNGEPGLP 112 G GS+G+ G G G GE G G GPPGP G+ G P Sbjct: 672 PPGIPGSLGKCGDPGLPGPDGEPGIPGIGFPGPPGPKGDQGFP 714 Score = 63.2 bits (152), Expect = 2e-10 Identities = 38/92 (41%), Positives = 44/92 (47%), Gaps = 14/92 (15%) Query: 23 GHPQPAGDDACSVQILVPGL--KGDAGEKGDKGAPGRPGRVGPTGEKGDMGDKGQKGSVG 80 G P GD +PGL G GE G G PG G +GP G++G G+ G G G Sbjct: 833 GKTGPKGDPG------IPGLDRSGFPGETGSPGIPGHQGEMGPLGQRGYPGNPGILGPPG 886 Query: 81 RHGKIGPIGSKGEKGDSGDIGPPGPNGEPGLP 112 G IG +G G IGPPGP G PG P Sbjct: 887 EDGVIGMMGFPGA------IGPPGPPGNPGTP 912 Score = 63.2 bits (152), Expect = 2e-10 Identities = 38/95 (40%), Positives = 47/95 (49%), Gaps = 3/95 (3%) Query: 21 PSGHPQPAGDDACSVQILVPGLKGD---AGEKGDKGAPGRPGRVGPTGEKGDMGDKGQKG 77 P+G P GD ++ PG G AG +G G+PG PG G G GD+G KG KG Sbjct: 1069 PTGDPGLPGDMGKKGEMGQPGPPGHLGPAGPEGAPGSPGSPGLPGKPGPHGDLGFKGIKG 1128 Query: 78 SVGRHGKIGPIGSKGEKGDSGDIGPPGPNGEPGLP 112 +G G GP G G G G +G G G G+P Sbjct: 1129 LLGPPGIRGPPGLPGFPGSPGPMGIRGDQGRDGIP 1163 Score = 61.2 bits (147), Expect = 9e-10 Identities = 37/88 (42%), Positives = 42/88 (47%), Gaps = 4/88 (4%) Query: 27 PAGDDACSV----QILVPGLKGDAGEKGDKGAPGRPGRVGPTGEKGDMGDKGQKGSVGRH 82 PA C Q G KG+ GEKG G PG PG+ G TG +G G +G KG G Sbjct: 25 PAASKGCVCKDKGQCFCDGAKGEKGEKGFPGPPGSPGQKGFTGPEGLPGPQGPKGFPGLP 84 Query: 83 GKIGPIGSKGEKGDSGDIGPPGPNGEPG 110 G G G +G G G G PG G PG Sbjct: 85 GLTGSKGVRGISGLPGFSGSPGLPGTPG 112 Score = 60.8 bits (146), Expect = 1e-09 Identities = 35/80 (43%), Positives = 43/80 (53%), Gaps = 7/80 (8%) Query: 40 PGLKGDAGEKGDKGAPGRP-GRVGPTGEKGDMGDKGQKG------SVGRHGKIGPIGSKG 92 PG +GD G KG+KG +P G+VG G+ G G G+KG + G G GP G Sbjct: 528 PGAQGDPGLKGEKGETLQPEGQVGVPGDPGLRGQPGRKGLDGIPGTPGVKGLPGPKGELA 587 Query: 93 EKGDSGDIGPPGPNGEPGLP 112 G+ GD GPPG G PG P Sbjct: 588 LSGEKGDQGPPGDPGSPGSP 607 Score = 60.8 bits (146), Expect = 1e-09 Identities = 41/111 (36%), Positives = 49/111 (44%), Gaps = 24/111 (21%) Query: 23 GHPQPAGDDACSVQILVPGLKGDAGEKGDKGAPGRPGRVGPTGEKG--DMGDKGQKGSVG 80 G P P G+ A S G KGD G GD G+PG PG GP G G G+ G +G+ G Sbjct: 578 GLPGPKGELALS------GEKGDQGPPGDPGSPGSPGPAGPAGPPGYGPQGEPGLQGTQG 631 Query: 81 RHGKIGPIGSKGEKGD----------------SGDIGPPGPNGEPGLPCEC 115 G GP G G +G+ G GP GP G PG +C Sbjct: 632 VPGAPGPPGEAGPRGELSVSTPVPGPPGPPGPPGHPGPQGPPGIPGSLGKC 682 Score = 60.8 bits (146), Expect = 1e-09 Identities = 42/112 (37%), Positives = 51/112 (45%), Gaps = 10/112 (8%) Query: 9 GVLISLAFLSLL-PSGHPQPAGDDACSVQILVPGLKGDAGEKGDKGAPGRPGRVGPT--- 64 GV+ + F + P G P G +PG+KG G G KG G G GP+ Sbjct: 889 GVIGMMGFPGAIGPPGPPGNPGTPGQRGSPGIPGVKGQRGTPGAKGEQGDKGNPGPSEIS 948 Query: 65 ---GEKGDMGDK---GQKGSVGRHGKIGPIGSKGEKGDSGDIGPPGPNGEPG 110 G+KG+ G K G G G G G G KG KG G GPPGP G+ G Sbjct: 949 HVIGDKGEPGLKGFAGNPGEKGNRGVPGMPGLKGLKGLPGPAGPPGPRGDLG 1000 Score = 60.8 bits (146), Expect = 1e-09 Identities = 32/77 (41%), Positives = 39/77 (50%), Gaps = 6/77 (7%) Query: 40 PGLKGDAGEKGDKGAPGR------PGRVGPTGEKGDMGDKGQKGSVGRHGKIGPIGSKGE 93 PG G G G +G PG PG GP G G+ G +G+ G G G +GP G +G+ Sbjct: 1333 PGPIGPKGPPGVRGDPGTLKIISLPGSPGPPGTPGEPGMQGEPGPPGPPGNLGPCGPRGK 1392 Query: 94 KGDSGDIGPPGPNGEPG 110 G G G PGP GE G Sbjct: 1393 PGKDGKPGTPGPAGEKG 1409 Score = 60.1 bits (144), Expect = 2e-09 Identities = 44/110 (40%), Positives = 52/110 (47%), Gaps = 26/110 (23%) Query: 22 SGHPQPAGDDACSVQILVPGLKGDA-GEKGDKGAPGRPGRVGPTG--------EKGDMGD 72 +G P P G V + P + D GEKGDKGA G PG GP+G EKG GD Sbjct: 235 TGPPGPPG--TVIVTLTGPDNRTDLKGEKGDKGAMGEPGPPGPSGLPGESYGSEKGAPGD 292 Query: 73 KGQKGSVGRHGKIGPIGSKGEKGD---------------SGDIGPPGPNG 107 G +G G+ G G GS+G KG+ GDIGPPG G Sbjct: 293 PGLQGKPGKDGVPGFPGSEGVKGNRGFPGLMGEDGIKGQKGDIGPPGFRG 342 Score = 60.1 bits (144), Expect = 2e-09 Identities = 31/73 (42%), Positives = 38/73 (52%) Query: 40 PGLKGDAGEKGDKGAPGRPGRVGPTGEKGDMGDKGQKGSVGRHGKIGPIGSKGEKGDSGD 99 PG G G++G G PG G+ G G KG+ GDKG G IG G G KG +G+ Sbjct: 906 PGNPGTPGQRGSPGIPGVKGQRGTPGAKGEQGDKGNPGPSEISHVIGDKGEPGLKGFAGN 965 Query: 100 IGPPGPNGEPGLP 112 G G G PG+P Sbjct: 966 PGEKGNRGVPGMP 978 Score = 58.5 bits (140), Expect = 6e-09 Identities = 34/74 (45%), Positives = 38/74 (51%), Gaps = 3/74 (4%) Query: 41 GLKGDAGEKGDKGAPGRPGRV--GPTGEKGDMGDKGQKGSVGRHGKIGPIGSKGEKGDSG 98 G +GD G+ G G G PGR GP G +G G G KG GR GK GP G G G Sbjct: 789 GPRGDPGQPGPPGEQGPPGRCIEGPRGAQGLPGLNGLKGQQGRRGKTGPKGDPGIPGLDR 848 Query: 99 DIGPPGPNGEPGLP 112 G PG G PG+P Sbjct: 849 S-GFPGETGSPGIP 861 Score = 58.5 bits (140), Expect = 6e-09 Identities = 34/87 (39%), Positives = 46/87 (52%), Gaps = 1/87 (1%) Query: 13 SLAFLSLLPS-GHPQPAGDDACSVQILVPGLKGDAGEKGDKGAPGRPGRVGPTGEKGDMG 71 +L +SL S G P G+ + PG G+ G G +G PG+ G+ G G G+ G Sbjct: 1350 TLKIISLPGSPGPPGTPGEPGMQGEPGPPGPPGNLGPCGPRGKPGKDGKPGTPGPAGEKG 1409 Query: 72 DKGQKGSVGRHGKIGPIGSKGEKGDSG 98 +KG KG G G G G KG++GDSG Sbjct: 1410 NKGSKGEPGPAGSDGLPGLKGKRGDSG 1436 Score = 58.2 bits (139), Expect = 8e-09 Identities = 40/93 (43%), Positives = 44/93 (47%), Gaps = 21/93 (22%) Query: 40 PGLKGDAGEK----------GDKGAPGRPGR------VGPTGEKGDMGDKGQ---KGSVG 80 PGLKG+ GE GD G G+PGR G G KG G KG+ G G Sbjct: 534 PGLKGEKGETLQPEGQVGVPGDPGLRGQPGRKGLDGIPGTPGVKGLPGPKGELALSGEKG 593 Query: 81 RHGKIGPIGSKGEKGDSGDIGPP--GPNGEPGL 111 G G GS G G +G GPP GP GEPGL Sbjct: 594 DQGPPGDPGSPGSPGPAGPAGPPGYGPQGEPGL 626 Score = 57.4 bits (137), Expect = 1e-08 Identities = 34/69 (49%), Positives = 38/69 (55%), Gaps = 3/69 (4%) Query: 44 GDAGEKGDKGAPGRPGRVGPTGEKGDMGDKGQKGSVGRHGKIGPIGSKGEKGDSGDIGPP 103 G GEKG+KG PG PG G G G G G +G G G G GSKG +G S G P Sbjct: 43 GAKGEKGEKGFPGPPGSPGQKGFTGPEGLPGPQGPKGFPGLPGLTGSKGVRGIS---GLP 99 Query: 104 GPNGEPGLP 112 G +G PGLP Sbjct: 100 GFSGSPGLP 108 Score = 56.6 bits (135), Expect = 2e-08 Identities = 34/77 (44%), Positives = 38/77 (49%), Gaps = 4/77 (5%) Query: 40 PGLKGDAGEKGDKGAPGRPGRVGPTGEKGDMGDKGQKGSVGRHGKIGPIGSKGEKGDS-- 97 PGL G G G KG PGR G G G G G+ G G G G G G KGEKG++ Sbjct: 486 PGLPGLPGLHGVKGIPGRQGAAGLKGSPGSPGNTGLPGFPGFPGAQGDPGLKGEKGETLQ 545 Query: 98 --GDIGPPGPNGEPGLP 112 G +G PG G G P Sbjct: 546 PEGQVGVPGDPGLRGQP 562 Score = 56.2 bits (134), Expect = 3e-08 Identities = 35/92 (38%), Positives = 41/92 (44%), Gaps = 12/92 (13%) Query: 21 PSGHPQPAGDDACSVQILVPGLKGDAGEKGDKGAPGRPGRVGPTGEKGDMGDKGQKGSVG 80 P G P P G PGL G G KG +G G P G G G G G+ G Sbjct: 68 PEGLPGPQGPKG------FPGLPGLTGSKGVRGISGLP------GFSGSPGLPGTPGNTG 115 Query: 81 RHGKIGPIGSKGEKGDSGDIGPPGPNGEPGLP 112 +G +G G G KG+ G G PG G PG+P Sbjct: 116 PYGLVGVPGCSGSKGEQGFPGLPGTLGYPGIP 147 Score = 55.8 bits (133), Expect = 4e-08 Identities = 40/117 (34%), Positives = 50/117 (42%), Gaps = 37/117 (31%) Query: 35 VQILVPGLKGDAGEKGDKGAPGRPGR------------------VGPTGEKGDMGD---- 72 +++ G G G G +G PG PG +GP G KG MG+ Sbjct: 165 IELDAKGDPGLPGAPGPQGLPGPPGFPGPVGPPGPPGFFGFPGAMGPRGPKGHMGERVIG 224 Query: 73 -KGQKGSVGRHGKIGPIGS--------------KGEKGDSGDIGPPGPNGEPGLPCE 114 KG++G G G GP G+ KGEKGD G +G PGP G GLP E Sbjct: 225 HKGERGVKGLTGPPGPPGTVIVTLTGPDNRTDLKGEKGDKGAMGEPGPPGPSGLPGE 281 Score = 55.1 bits (131), Expect = 6e-08 Identities = 46/120 (38%), Positives = 50/120 (41%), Gaps = 28/120 (23%) Query: 21 PSGHPQPAGDDACSVQILV-----PGLKGDAGEKGDKG--------------APGRPGRV 61 PSG P G S L PGLKG GE+G G +PG PG Sbjct: 373 PSGPPGVPGSPGSSRPGLRGAPGWPGLKGSKGERGRPGKDAMGTPGSPGCAGSPGLPGSP 432 Query: 62 GPTGEKGDM-------GDKGQKGSVGRHGKIGPIGSKGEKGDSGDIGP--PGPNGEPGLP 112 GP G GD+ GD G G +G G G G KGE G P PGP G PGLP Sbjct: 433 GPPGPPGDIVFRKGPPGDHGLPGYLGSPGIPGVDGPKGEPGLLCTQCPYIPGPPGLPGLP 492 Score = 54.3 bits (129), Expect = 1e-07 Identities = 37/99 (37%), Positives = 41/99 (41%), Gaps = 31/99 (31%) Query: 40 PGLKGDAGEKGDKGAP--------------------GRPGRVGPTGEKGDMGDKGQKGSV 79 PG+ G AG KG KGAP G G GP G G +G G G Sbjct: 144 PGIPGAAGLKGQKGAPAKEEDIELDAKGDPGLPGAPGPQGLPGPPGFPGPVGPPGPPGFF 203 Query: 80 GRHGKIGP-----------IGSKGEKGDSGDIGPPGPNG 107 G G +GP IG KGE+G G GPPGP G Sbjct: 204 GFPGAMGPRGPKGHMGERVIGHKGERGVKGLTGPPGPPG 242 Score = 52.8 bits (125), Expect = 3e-07 Identities = 35/84 (41%), Positives = 40/84 (47%), Gaps = 10/84 (11%) Query: 41 GLKGDAGEKGDKGAPGRPGRVGPTGEKGDMGDKGQ----KGSVGRHGKIGPIGSKGEKGD 96 GLKG G G+ G PG PG G G+ G G+KG+ +G VG G G G G KG Sbjct: 508 GLKGSPGSPGNTGLPGFPGFPGAQGDPGLKGEKGETLQPEGQVGVPGDPGLRGQPGRKGL 567 Query: 97 SGDIGPPG------PNGEPGLPCE 114 G G PG P GE L E Sbjct: 568 DGIPGTPGVKGLPGPKGELALSGE 591 Score = 52.4 bits (124), Expect = 4e-07 Identities = 32/71 (45%), Positives = 34/71 (47%) Query: 40 PGLKGDAGEKGDKGAPGRPGRVGPTGEKGDMGDKGQKGSVGRHGKIGPIGSKGEKGDSGD 99 PG G G+KG G G PG GP G G G G KG G G G GS G G G+ Sbjct: 54 PGPPGSPGQKGFTGPEGLPGPQGPKGFPGLPGLTGSKGVRGISGLPGFSGSPGLPGTPGN 113 Query: 100 IGPPGPNGEPG 110 GP G G PG Sbjct: 114 TGPYGLVGVPG 124 Score = 51.2 bits (121), Expect = 9e-07 Identities = 42/123 (34%), Positives = 52/123 (42%), Gaps = 25/123 (20%) Query: 23 GHPQPAGDDACSVQILVPGLKGDAGEKGDKGAPGRPGRVGPTGEKGDM------------ 70 G P P GD + G GD G G G+PG PG GP GE G + Sbjct: 433 GPPGPPGDI-----VFRKGPPGDHGLPGYLGSPGIPGVDGPKGEPGLLCTQCPYIPGPPG 487 Query: 71 -----GDKGQKGSVGRHGKIGPIGSKGEKGDSG---DIGPPGPNGEPGLPCECSQLRKAI 122 G G KG GR G G GS G G++G G PG G+PGL E + + Sbjct: 488 LPGLPGLHGVKGIPGRQGAAGLKGSPGSPGNTGLPGFPGFPGAQGDPGLKGEKGETLQPE 547 Query: 123 GEM 125 G++ Sbjct: 548 GQV 550 Score = 50.1 bits (118), Expect = 2e-06 Identities = 32/81 (39%), Positives = 37/81 (45%), Gaps = 1/81 (1%) Query: 33 CSVQILVPGLKGDAGEKGDKGAPGRPGRVGPTGEKGDMGDKGQKGSVGRHGKIGPIGSKG 92 C+ +PG G G G G G PGR G G KG G G G G G G G G Sbjct: 476 CTQCPYIPGPPGLPGLPGLHGVKGIPGRQGAAGLKGSPGSPGNTGLPGFPGFPGAQGDPG 535 Query: 93 EKGDSGD-IGPPGPNGEPGLP 112 KG+ G+ + P G G PG P Sbjct: 536 LKGEKGETLQPEGQVGVPGDP 556 Score = 48.5 bits (114), Expect = 6e-06 Identities = 35/82 (42%), Positives = 37/82 (45%), Gaps = 13/82 (15%) Query: 40 PGLKGD---AGEKGDKGAPGRPGRVGPT------GEKGDMGDKGQKGSVGRHGKIGPIGS 90 PGL G+ G+KGD G PG GPT EKGD G G G G G GP G Sbjct: 320 PGLMGEDGIKGQKGDIGPPGFR---GPTEYYDTYQEKGDEGTPGPPGPRGARGPQGPSGP 376 Query: 91 KGEKGDSGDIGPPGPNGEPGLP 112 G G G PG G PG P Sbjct: 377 PGVPGSPGS-SRPGLRGAPGWP 397 Score = 43.9 bits (102), Expect = 1e-04 Identities = 22/47 (46%), Positives = 25/47 (53%) Query: 66 EKGDMGDKGQKGSVGRHGKIGPIGSKGEKGDSGDIGPPGPNGEPGLP 112 +KG G KG G G GP GS G+KG +G G PGP G G P Sbjct: 35 DKGQCFCDGAKGEKGEKGFPGPPGSPGQKGFTGPEGLPGPQGPKGFP 81 Score = 33.1 bits (74), Expect = 0.26 Identities = 24/69 (34%), Positives = 29/69 (42%), Gaps = 10/69 (14%) Query: 23 GHPQPAGDDACSVQILVPGLKGDAGEKGDKGAPGRPGRVGPTGEKGDMGDKGQKGSV-GR 81 G P PAG+ G KG GE G G+ G PG G G+ G +G V R Sbjct: 1400 GTPGPAGEK---------GNKGSKGEPGPAGSDGLPGLKGKRGDSGSPATWTTRGFVFTR 1450 Query: 82 HGKIGPIGS 90 H + I S Sbjct: 1451 HSQTTAIPS 1459 >gi|89142730 alpha 3 type IV collagen isoform 1 precursor [Homo sapiens] Length = 1670 Score = 80.1 bits (196), Expect = 2e-15 Identities = 44/90 (48%), Positives = 49/90 (54%), Gaps = 12/90 (13%) Query: 23 GHPQPAGDDACSVQILVPGLKGDAGEKGDKGAPGRPGRVGPTGEKGDMGDKGQKGSVGRH 82 G P P GD PGL GD G+KG+ G PG PG +GP G + G G GS G Sbjct: 1065 GPPGPTGD---------PGLPGDMGKKGEMGQPGPPGHLGPAGPE---GAPGSPGSPGLP 1112 Query: 83 GKIGPIGSKGEKGDSGDIGPPGPNGEPGLP 112 GK GP G G KG G +GPPG G PGLP Sbjct: 1113 GKPGPHGDLGFKGIKGLLGPPGIRGPPGLP 1142 Score = 77.8 bits (190), Expect = 9e-15 Identities = 39/91 (42%), Positives = 46/91 (50%) Query: 21 PSGHPQPAGDDACSVQILVPGLKGDAGEKGDKGAPGRPGRVGPTGEKGDMGDKGQKGSVG 80 P G P GD I +PG G G G+ G G PG GP G G G +G+ G G Sbjct: 1338 PKGPPGVRGDPGTLKIISLPGSPGPPGTPGEPGMQGEPGPPGPPGNLGPCGPRGKPGKDG 1397 Query: 81 RHGKIGPIGSKGEKGDSGDIGPPGPNGEPGL 111 + G GP G KG KG G+ GP G +G PGL Sbjct: 1398 KPGTPGPAGEKGNKGSKGEPGPAGSDGLPGL 1428 Score = 73.9 bits (180), Expect = 1e-13 Identities = 45/110 (40%), Positives = 52/110 (47%), Gaps = 27/110 (24%) Query: 23 GHPQPAGDDACSVQILVPGLKGDAGEKGDKGAPGRPGRVGPTGE---------KGDMGDK 73 GHP P G PG GD G G GAPG PG GP G+ KG+ G+ Sbjct: 1274 GHPGPKGP---------PGTAGDMGPPGRLGAPGTPGLPGPRGDPGFQGFPGVKGEKGNP 1324 Query: 74 GQKGSVGRHGKIGPIGSKGEKGDSGDI---------GPPGPNGEPGLPCE 114 G GS+G G IGP G G +GD G + GPPG GEPG+ E Sbjct: 1325 GFLGSIGPPGPIGPKGPPGVRGDPGTLKIISLPGSPGPPGTPGEPGMQGE 1374 Score = 70.5 bits (171), Expect = 1e-12 Identities = 37/76 (48%), Positives = 45/76 (59%), Gaps = 5/76 (6%) Query: 40 PGLKGDAGEKGDKGAPG-----RPGRVGPTGEKGDMGDKGQKGSVGRHGKIGPIGSKGEK 94 PGL G G +GDKG PG RPG GPTG+ G GD G+KG +G+ G G +G G + Sbjct: 1041 PGLPGIHGLQGDKGEPGYSEGTRPGPPGPTGDPGLPGDMGKKGEMGQPGPPGHLGPAGPE 1100 Query: 95 GDSGDIGPPGPNGEPG 110 G G G PG G+PG Sbjct: 1101 GAPGSPGSPGLPGKPG 1116 Score = 68.9 bits (167), Expect = 4e-12 Identities = 40/93 (43%), Positives = 49/93 (52%), Gaps = 3/93 (3%) Query: 23 GHPQPAGDDACSVQILVP-GLKGDAGEKGDKGAPGRPGRVGPTGEKGDMGDKGQKGSVGR 81 G P PAG+ + + P G +G+ G +G KG G PG G G KG MGD G +G G Sbjct: 1161 GIPGPAGEKGETGLLRAPPGPRGNPGAQGAKGDRGAPGFPGLPGRKGAMGDAGPRGPTGI 1220 Query: 82 HGKIGPIGSKGE--KGDSGDIGPPGPNGEPGLP 112 G GP G G G +G+ GPPG G PG P Sbjct: 1221 EGFPGPPGLPGAIIPGQTGNRGPPGSRGSPGAP 1253 Score = 68.9 bits (167), Expect = 4e-12 Identities = 39/91 (42%), Positives = 46/91 (50%), Gaps = 4/91 (4%) Query: 23 GHPQPAGDDACSVQILVPGLKGDAGEKGDKGAPGRPGRVGPTGEKGDMGDKGQKGSVGRH 82 G P P GD PG+KG+ G G G+ G PG +GP G G GD G + Sbjct: 1301 GLPGPRGDPGFQG---FPGVKGEKGNPGFLGSIGPPGPIGPKGPPGVRGDPGTLKIISLP 1357 Query: 83 GKIGPIGSKGEKGDSGDIGPPGPNGEPGLPC 113 G GP G+ GE G G+ GPPGP G G PC Sbjct: 1358 GSPGPPGTPGEPGMQGEPGPPGPPGNLG-PC 1387 Score = 68.6 bits (166), Expect = 6e-12 Identities = 37/88 (42%), Positives = 47/88 (53%), Gaps = 5/88 (5%) Query: 23 GHPQPAGDDACSVQILVPGLKGDAGEKGDKGAPGRPGRVGPTGEKGDMGDKGQKGSVGRH 82 G P P G ++PG G+ G G +G+PG PG GP G +G KG KGS+G Sbjct: 1222 GFPGPPGLPGA----IIPGQTGNRGPPGSRGSPGAPGPPGPPGSH-VIGIKGDKGSMGHP 1276 Query: 83 GKIGPIGSKGEKGDSGDIGPPGPNGEPG 110 G GP G+ G+ G G +G PG G PG Sbjct: 1277 GPKGPPGTAGDMGPPGRLGAPGTPGLPG 1304 Score = 68.2 bits (165), Expect = 7e-12 Identities = 39/88 (44%), Positives = 46/88 (52%), Gaps = 15/88 (17%) Query: 40 PGLKGDAG---EKGDKGAPGRPGR---------VGPTGEKGDMGDKGQKGSVGRHG---K 84 PGLKG AG EKG++G PG PG GP G +GD+G G G G G Sbjct: 957 PGLKGFAGNPGEKGNRGVPGMPGLKGLKGLPGPAGPPGPRGDLGSTGNPGEPGLRGIPGS 1016 Query: 85 IGPIGSKGEKGDSGDIGPPGPNGEPGLP 112 +G +G G KG G +G PG G PGLP Sbjct: 1017 MGNMGMPGSKGKRGTLGFPGRAGRPGLP 1044 Score = 67.8 bits (164), Expect = 1e-11 Identities = 37/81 (45%), Positives = 44/81 (54%), Gaps = 9/81 (11%) Query: 40 PGLKGDAGEKGDKGAPGRPGRVGPTGEKGDMGDKGQKGSVGRHGKIGPIGSKGEKGDSGD 99 PG+ G GE G G G PG +GP G G+ G GQ+GS G G G G+ G KG+ GD Sbjct: 879 PGILGPPGEDGVIGMMGFPGAIGPPGPPGNPGTPGQRGSPGIPGVKGQRGTPGAKGEQGD 938 Query: 100 IGPPGPN---------GEPGL 111 G PGP+ GEPGL Sbjct: 939 KGNPGPSEISHVIGDKGEPGL 959 Score = 67.4 bits (163), Expect = 1e-11 Identities = 40/98 (40%), Positives = 48/98 (48%), Gaps = 5/98 (5%) Query: 23 GHPQPAGDDACSVQILVPGLKGDAGEKGDKGAP-----GRPGRVGPTGEKGDMGDKGQKG 77 G P G C ++ PGL G G G KG P G PG G GE+G+ G+ G+ G Sbjct: 712 GFPGTKGSLGCPGKMGEPGLPGKPGLPGAKGEPAVAMPGGPGTPGFPGERGNSGEHGEIG 771 Query: 78 SVGRHGKIGPIGSKGEKGDSGDIGPPGPNGEPGLPCEC 115 G G G G++G G GD G PGP GE G P C Sbjct: 772 LPGLPGLPGTPGNEGLDGPRGDPGQPGPPGEQGPPGRC 809 Score = 66.2 bits (160), Expect = 3e-11 Identities = 42/97 (43%), Positives = 47/97 (48%), Gaps = 7/97 (7%) Query: 21 PSGHPQPAGDDACSVQILVPGL------KGDAGEKGDKGAPGRPGRVGPTGEKGDMGDKG 74 P GH PAG + PGL GD G KG KG G PG GP G G G G Sbjct: 1090 PPGHLGPAGPEGAPGSPGSPGLPGKPGPHGDLGFKGIKGLLGPPGIRGPPGLPGFPGSPG 1149 Query: 75 QKGSVGRHGKIGPIGSKGEKGDSGDI-GPPGPNGEPG 110 G G G+ G G GEKG++G + PPGP G PG Sbjct: 1150 PMGIRGDQGRDGIPGPAGEKGETGLLRAPPGPRGNPG 1186 Score = 66.2 bits (160), Expect = 3e-11 Identities = 41/87 (47%), Positives = 45/87 (51%), Gaps = 14/87 (16%) Query: 40 PGLKGD--AGEKGDKGAPGRPGRVGPTGEKGDMGDKGQKGSVGRHGKIGPIGS------- 90 PG G G KGDKG+ G PG GP G GDMG G+ G+ G G GP G Sbjct: 1256 PGPPGSHVIGIKGDKGSMGHPGPKGPPGTAGDMGPPGRLGAPGTPGLPGPRGDPGFQGFP 1315 Query: 91 --KGEKGDS---GDIGPPGPNGEPGLP 112 KGEKG+ G IGPPGP G G P Sbjct: 1316 GVKGEKGNPGFLGSIGPPGPIGPKGPP 1342 Score = 65.5 bits (158), Expect = 5e-11 Identities = 38/101 (37%), Positives = 48/101 (47%), Gaps = 9/101 (8%) Query: 21 PSGHPQPAGDDACSVQILVPGL--KGDAGEKGDKGAPGRPGRVGPTGEKGDM-------G 71 P G P G + PG +G+ G +G +G PG PG G G +G++ G Sbjct: 597 PPGDPGSPGSPGPAGPAGPPGYGPQGEPGLQGTQGVPGAPGPPGEAGPRGELSVSTPVPG 656 Query: 72 DKGQKGSVGRHGKIGPIGSKGEKGDSGDIGPPGPNGEPGLP 112 G G G G GP G G G GD G PGP+GEPG+P Sbjct: 657 PPGPPGPPGHPGPQGPPGIPGSLGKCGDPGLPGPDGEPGIP 697 Score = 65.5 bits (158), Expect = 5e-11 Identities = 43/107 (40%), Positives = 48/107 (44%), Gaps = 22/107 (20%) Query: 21 PSGHPQPAGDDACSVQILVPGLKGDAGEKGDKGAPGRPGRVG--------PTGEKGDMGD 72 P GHP P G PG+ G G+ GD G PG G G P G KGD G Sbjct: 663 PPGHPGPQGP---------PGIPGSLGKCGDPGLPGPDGEPGIPGIGFPGPPGPKGDQGF 713 Query: 73 KGQKGSVGRHGKIGPIGSKGEKGDSGDIGP-----PGPNGEPGLPCE 114 G KGS+G GK+G G G+ G G G PG G PG P E Sbjct: 714 PGTKGSLGCPGKMGEPGLPGKPGLPGAKGEPAVAMPGGPGTPGFPGE 760 Score = 64.7 bits (156), Expect = 8e-11 Identities = 34/81 (41%), Positives = 41/81 (50%), Gaps = 9/81 (11%) Query: 39 VPGLKGDAGEKGDKGAPGRPGRVGPTGEKGDMGDKGQKGSV---------GRHGKIGPIG 89 VPG G G KG++G PG G G G+KGD+G G +G G G GP G Sbjct: 304 VPGFPGSEGVKGNRGFPGLMGEDGIKGQKGDIGPPGFRGPTEYYDTYQEKGDEGTPGPPG 363 Query: 90 SKGEKGDSGDIGPPGPNGEPG 110 +G +G G GPPG G PG Sbjct: 364 PRGARGPQGPSGPPGVPGSPG 384 Score = 64.7 bits (156), Expect = 8e-11 Identities = 36/91 (39%), Positives = 45/91 (49%), Gaps = 17/91 (18%) Query: 39 VPGLKGDAGEKGDKGAPGRPGRVGPTGEKGDMGDKGQKGSVGRHGKIGPIGSKGE----- 93 +PG G G +GD G+ G PG G G G MG+ G GS G+ G +G G G Sbjct: 986 LPGPAGPPGPRGDLGSTGNPGEPGLRGIPGSMGNMGMPGSKGKRGTLGFPGRAGRPGLPG 1045 Query: 94 ----KGDSGD--------IGPPGPNGEPGLP 112 +GD G+ GPPGP G+PGLP Sbjct: 1046 IHGLQGDKGEPGYSEGTRPGPPGPTGDPGLP 1076 Score = 64.3 bits (155), Expect = 1e-10 Identities = 36/85 (42%), Positives = 41/85 (48%), Gaps = 12/85 (14%) Query: 40 PGLKGDAGEKG------------DKGAPGRPGRVGPTGEKGDMGDKGQKGSVGRHGKIGP 87 PG KG+ G+KG DKG PG G G GEKG+ G G G G G GP Sbjct: 930 PGAKGEQGDKGNPGPSEISHVIGDKGEPGLKGFAGNPGEKGNRGVPGMPGLKGLKGLPGP 989 Query: 88 IGSKGEKGDSGDIGPPGPNGEPGLP 112 G G +GD G G PG G G+P Sbjct: 990 AGPPGPRGDLGSTGNPGEPGLRGIP 1014 Score = 63.5 bits (153), Expect = 2e-10 Identities = 39/99 (39%), Positives = 48/99 (48%), Gaps = 11/99 (11%) Query: 23 GHPQPAG--DDACSVQILVPGLKGDAGEKGDKGAPGRPGRVGPTGEKGDMGDKGQKGSVG 80 G P P+G ++ + PG G G+ G G PG PG G G +G G G+ G G Sbjct: 271 GPPGPSGLPGESYGSEKGAPGDPGLQGKPGKDGVPGFPGSEGVKGNRGFPGLMGEDGIKG 330 Query: 81 RHGKIGPIGSKG---------EKGDSGDIGPPGPNGEPG 110 + G IGP G +G EKGD G GPPGP G G Sbjct: 331 QKGDIGPPGFRGPTEYYDTYQEKGDEGTPGPPGPRGARG 369 Score = 63.5 bits (153), Expect = 2e-10 Identities = 37/92 (40%), Positives = 42/92 (45%), Gaps = 6/92 (6%) Query: 27 PAGDDACSVQILVPGLKGDAGEKGDKGAPGRPGRVGPTGEKGDMGDKGQKGSVGRHGKIG 86 P G+D + PG G G G+ G PG+ G G G KG G G KG G G G Sbjct: 884 PPGEDGVIGMMGFPGAIGPPGPPGNPGTPGQRGSPGIPGVKGQRGTPGAKGEQGDKGNPG 943 Query: 87 P------IGSKGEKGDSGDIGPPGPNGEPGLP 112 P IG KGE G G G PG G G+P Sbjct: 944 PSEISHVIGDKGEPGLKGFAGNPGEKGNRGVP 975 Score = 63.2 bits (152), Expect = 2e-10 Identities = 40/98 (40%), Positives = 44/98 (44%), Gaps = 5/98 (5%) Query: 18 SLLPSGHPQPAGDDACSVQILVPGLKGDAGEKGDKGAPGRPGRVGPTGEKGDMGDKGQKG 77 +L P G GD Q GL G G G KG PG G + +GEKGD G G G Sbjct: 543 TLQPEGQVGVPGDPGLRGQPGRKGLDGIPGTPGVKGLPGPKGELALSGEKGDQGPPGDPG 602 Query: 78 SVGRHGKIGP-----IGSKGEKGDSGDIGPPGPNGEPG 110 S G G GP G +GE G G G PG G PG Sbjct: 603 SPGSPGPAGPAGPPGYGPQGEPGLQGTQGVPGAPGPPG 640 Score = 63.2 bits (152), Expect = 2e-10 Identities = 41/103 (39%), Positives = 47/103 (45%), Gaps = 11/103 (10%) Query: 21 PSGHPQ--PAGDDACSVQILVPGLKGDAGEKGDKG-------APGRPGRVGPTGEKGDMG 71 P+G P P G+ VPG G GE G +G PG PG GP G G G Sbjct: 612 PAGPPGYGPQGEPGLQGTQGVPGAPGPPGEAGPRGELSVSTPVPGPPGPPGPPGHPGPQG 671 Query: 72 DKGQKGSVGRHGKIGPIGSKGEKG--DSGDIGPPGPNGEPGLP 112 G GS+G+ G G G GE G G GPPGP G+ G P Sbjct: 672 PPGIPGSLGKCGDPGLPGPDGEPGIPGIGFPGPPGPKGDQGFP 714 Score = 63.2 bits (152), Expect = 2e-10 Identities = 38/92 (41%), Positives = 44/92 (47%), Gaps = 14/92 (15%) Query: 23 GHPQPAGDDACSVQILVPGL--KGDAGEKGDKGAPGRPGRVGPTGEKGDMGDKGQKGSVG 80 G P GD +PGL G GE G G PG G +GP G++G G+ G G G Sbjct: 833 GKTGPKGDPG------IPGLDRSGFPGETGSPGIPGHQGEMGPLGQRGYPGNPGILGPPG 886 Query: 81 RHGKIGPIGSKGEKGDSGDIGPPGPNGEPGLP 112 G IG +G G IGPPGP G PG P Sbjct: 887 EDGVIGMMGFPGA------IGPPGPPGNPGTP 912 Score = 63.2 bits (152), Expect = 2e-10 Identities = 38/95 (40%), Positives = 47/95 (49%), Gaps = 3/95 (3%) Query: 21 PSGHPQPAGDDACSVQILVPGLKGD---AGEKGDKGAPGRPGRVGPTGEKGDMGDKGQKG 77 P+G P GD ++ PG G AG +G G+PG PG G G GD+G KG KG Sbjct: 1069 PTGDPGLPGDMGKKGEMGQPGPPGHLGPAGPEGAPGSPGSPGLPGKPGPHGDLGFKGIKG 1128 Query: 78 SVGRHGKIGPIGSKGEKGDSGDIGPPGPNGEPGLP 112 +G G GP G G G G +G G G G+P Sbjct: 1129 LLGPPGIRGPPGLPGFPGSPGPMGIRGDQGRDGIP 1163 Score = 61.2 bits (147), Expect = 9e-10 Identities = 37/88 (42%), Positives = 42/88 (47%), Gaps = 4/88 (4%) Query: 27 PAGDDACSV----QILVPGLKGDAGEKGDKGAPGRPGRVGPTGEKGDMGDKGQKGSVGRH 82 PA C Q G KG+ GEKG G PG PG+ G TG +G G +G KG G Sbjct: 25 PAASKGCVCKDKGQCFCDGAKGEKGEKGFPGPPGSPGQKGFTGPEGLPGPQGPKGFPGLP 84 Query: 83 GKIGPIGSKGEKGDSGDIGPPGPNGEPG 110 G G G +G G G G PG G PG Sbjct: 85 GLTGSKGVRGISGLPGFSGSPGLPGTPG 112 Score = 60.8 bits (146), Expect = 1e-09 Identities = 35/80 (43%), Positives = 43/80 (53%), Gaps = 7/80 (8%) Query: 40 PGLKGDAGEKGDKGAPGRP-GRVGPTGEKGDMGDKGQKG------SVGRHGKIGPIGSKG 92 PG +GD G KG+KG +P G+VG G+ G G G+KG + G G GP G Sbjct: 528 PGAQGDPGLKGEKGETLQPEGQVGVPGDPGLRGQPGRKGLDGIPGTPGVKGLPGPKGELA 587 Query: 93 EKGDSGDIGPPGPNGEPGLP 112 G+ GD GPPG G PG P Sbjct: 588 LSGEKGDQGPPGDPGSPGSP 607 Score = 60.8 bits (146), Expect = 1e-09 Identities = 41/111 (36%), Positives = 49/111 (44%), Gaps = 24/111 (21%) Query: 23 GHPQPAGDDACSVQILVPGLKGDAGEKGDKGAPGRPGRVGPTGEKG--DMGDKGQKGSVG 80 G P P G+ A S G KGD G GD G+PG PG GP G G G+ G +G+ G Sbjct: 578 GLPGPKGELALS------GEKGDQGPPGDPGSPGSPGPAGPAGPPGYGPQGEPGLQGTQG 631 Query: 81 RHGKIGPIGSKGEKGD----------------SGDIGPPGPNGEPGLPCEC 115 G GP G G +G+ G GP GP G PG +C Sbjct: 632 VPGAPGPPGEAGPRGELSVSTPVPGPPGPPGPPGHPGPQGPPGIPGSLGKC 682 Score = 60.8 bits (146), Expect = 1e-09 Identities = 42/112 (37%), Positives = 51/112 (45%), Gaps = 10/112 (8%) Query: 9 GVLISLAFLSLL-PSGHPQPAGDDACSVQILVPGLKGDAGEKGDKGAPGRPGRVGPT--- 64 GV+ + F + P G P G +PG+KG G G KG G G GP+ Sbjct: 889 GVIGMMGFPGAIGPPGPPGNPGTPGQRGSPGIPGVKGQRGTPGAKGEQGDKGNPGPSEIS 948 Query: 65 ---GEKGDMGDK---GQKGSVGRHGKIGPIGSKGEKGDSGDIGPPGPNGEPG 110 G+KG+ G K G G G G G G KG KG G GPPGP G+ G Sbjct: 949 HVIGDKGEPGLKGFAGNPGEKGNRGVPGMPGLKGLKGLPGPAGPPGPRGDLG 1000 Score = 60.8 bits (146), Expect = 1e-09 Identities = 32/77 (41%), Positives = 39/77 (50%), Gaps = 6/77 (7%) Query: 40 PGLKGDAGEKGDKGAPGR------PGRVGPTGEKGDMGDKGQKGSVGRHGKIGPIGSKGE 93 PG G G G +G PG PG GP G G+ G +G+ G G G +GP G +G+ Sbjct: 1333 PGPIGPKGPPGVRGDPGTLKIISLPGSPGPPGTPGEPGMQGEPGPPGPPGNLGPCGPRGK 1392 Query: 94 KGDSGDIGPPGPNGEPG 110 G G G PGP GE G Sbjct: 1393 PGKDGKPGTPGPAGEKG 1409 Score = 60.1 bits (144), Expect = 2e-09 Identities = 44/110 (40%), Positives = 52/110 (47%), Gaps = 26/110 (23%) Query: 22 SGHPQPAGDDACSVQILVPGLKGDA-GEKGDKGAPGRPGRVGPTG--------EKGDMGD 72 +G P P G V + P + D GEKGDKGA G PG GP+G EKG GD Sbjct: 235 TGPPGPPG--TVIVTLTGPDNRTDLKGEKGDKGAMGEPGPPGPSGLPGESYGSEKGAPGD 292 Query: 73 KGQKGSVGRHGKIGPIGSKGEKGD---------------SGDIGPPGPNG 107 G +G G+ G G GS+G KG+ GDIGPPG G Sbjct: 293 PGLQGKPGKDGVPGFPGSEGVKGNRGFPGLMGEDGIKGQKGDIGPPGFRG 342 Score = 60.1 bits (144), Expect = 2e-09 Identities = 31/73 (42%), Positives = 38/73 (52%) Query: 40 PGLKGDAGEKGDKGAPGRPGRVGPTGEKGDMGDKGQKGSVGRHGKIGPIGSKGEKGDSGD 99 PG G G++G G PG G+ G G KG+ GDKG G IG G G KG +G+ Sbjct: 906 PGNPGTPGQRGSPGIPGVKGQRGTPGAKGEQGDKGNPGPSEISHVIGDKGEPGLKGFAGN 965 Query: 100 IGPPGPNGEPGLP 112 G G G PG+P Sbjct: 966 PGEKGNRGVPGMP 978 Score = 58.5 bits (140), Expect = 6e-09 Identities = 34/74 (45%), Positives = 38/74 (51%), Gaps = 3/74 (4%) Query: 41 GLKGDAGEKGDKGAPGRPGRV--GPTGEKGDMGDKGQKGSVGRHGKIGPIGSKGEKGDSG 98 G +GD G+ G G G PGR GP G +G G G KG GR GK GP G G G Sbjct: 789 GPRGDPGQPGPPGEQGPPGRCIEGPRGAQGLPGLNGLKGQQGRRGKTGPKGDPGIPGLDR 848 Query: 99 DIGPPGPNGEPGLP 112 G PG G PG+P Sbjct: 849 S-GFPGETGSPGIP 861 Score = 58.5 bits (140), Expect = 6e-09 Identities = 34/87 (39%), Positives = 46/87 (52%), Gaps = 1/87 (1%) Query: 13 SLAFLSLLPS-GHPQPAGDDACSVQILVPGLKGDAGEKGDKGAPGRPGRVGPTGEKGDMG 71 +L +SL S G P G+ + PG G+ G G +G PG+ G+ G G G+ G Sbjct: 1350 TLKIISLPGSPGPPGTPGEPGMQGEPGPPGPPGNLGPCGPRGKPGKDGKPGTPGPAGEKG 1409 Query: 72 DKGQKGSVGRHGKIGPIGSKGEKGDSG 98 +KG KG G G G G KG++GDSG Sbjct: 1410 NKGSKGEPGPAGSDGLPGLKGKRGDSG 1436 Score = 58.2 bits (139), Expect = 8e-09 Identities = 40/93 (43%), Positives = 44/93 (47%), Gaps = 21/93 (22%) Query: 40 PGLKGDAGEK----------GDKGAPGRPGR------VGPTGEKGDMGDKGQ---KGSVG 80 PGLKG+ GE GD G G+PGR G G KG G KG+ G G Sbjct: 534 PGLKGEKGETLQPEGQVGVPGDPGLRGQPGRKGLDGIPGTPGVKGLPGPKGELALSGEKG 593 Query: 81 RHGKIGPIGSKGEKGDSGDIGPP--GPNGEPGL 111 G G GS G G +G GPP GP GEPGL Sbjct: 594 DQGPPGDPGSPGSPGPAGPAGPPGYGPQGEPGL 626 Score = 57.4 bits (137), Expect = 1e-08 Identities = 34/69 (49%), Positives = 38/69 (55%), Gaps = 3/69 (4%) Query: 44 GDAGEKGDKGAPGRPGRVGPTGEKGDMGDKGQKGSVGRHGKIGPIGSKGEKGDSGDIGPP 103 G GEKG+KG PG PG G G G G G +G G G G GSKG +G S G P Sbjct: 43 GAKGEKGEKGFPGPPGSPGQKGFTGPEGLPGPQGPKGFPGLPGLTGSKGVRGIS---GLP 99 Query: 104 GPNGEPGLP 112 G +G PGLP Sbjct: 100 GFSGSPGLP 108 Score = 56.6 bits (135), Expect = 2e-08 Identities = 34/77 (44%), Positives = 38/77 (49%), Gaps = 4/77 (5%) Query: 40 PGLKGDAGEKGDKGAPGRPGRVGPTGEKGDMGDKGQKGSVGRHGKIGPIGSKGEKGDS-- 97 PGL G G G KG PGR G G G G G+ G G G G G G KGEKG++ Sbjct: 486 PGLPGLPGLHGVKGIPGRQGAAGLKGSPGSPGNTGLPGFPGFPGAQGDPGLKGEKGETLQ 545 Query: 98 --GDIGPPGPNGEPGLP 112 G +G PG G G P Sbjct: 546 PEGQVGVPGDPGLRGQP 562 Score = 56.2 bits (134), Expect = 3e-08 Identities = 35/92 (38%), Positives = 41/92 (44%), Gaps = 12/92 (13%) Query: 21 PSGHPQPAGDDACSVQILVPGLKGDAGEKGDKGAPGRPGRVGPTGEKGDMGDKGQKGSVG 80 P G P P G PGL G G KG +G G P G G G G G+ G Sbjct: 68 PEGLPGPQGPKG------FPGLPGLTGSKGVRGISGLP------GFSGSPGLPGTPGNTG 115 Query: 81 RHGKIGPIGSKGEKGDSGDIGPPGPNGEPGLP 112 +G +G G G KG+ G G PG G PG+P Sbjct: 116 PYGLVGVPGCSGSKGEQGFPGLPGTLGYPGIP 147 Score = 55.8 bits (133), Expect = 4e-08 Identities = 40/117 (34%), Positives = 50/117 (42%), Gaps = 37/117 (31%) Query: 35 VQILVPGLKGDAGEKGDKGAPGRPGR------------------VGPTGEKGDMGD---- 72 +++ G G G G +G PG PG +GP G KG MG+ Sbjct: 165 IELDAKGDPGLPGAPGPQGLPGPPGFPGPVGPPGPPGFFGFPGAMGPRGPKGHMGERVIG 224 Query: 73 -KGQKGSVGRHGKIGPIGS--------------KGEKGDSGDIGPPGPNGEPGLPCE 114 KG++G G G GP G+ KGEKGD G +G PGP G GLP E Sbjct: 225 HKGERGVKGLTGPPGPPGTVIVTLTGPDNRTDLKGEKGDKGAMGEPGPPGPSGLPGE 281 Score = 55.1 bits (131), Expect = 6e-08 Identities = 46/120 (38%), Positives = 50/120 (41%), Gaps = 28/120 (23%) Query: 21 PSGHPQPAGDDACSVQILV-----PGLKGDAGEKGDKG--------------APGRPGRV 61 PSG P G S L PGLKG GE+G G +PG PG Sbjct: 373 PSGPPGVPGSPGSSRPGLRGAPGWPGLKGSKGERGRPGKDAMGTPGSPGCAGSPGLPGSP 432 Query: 62 GPTGEKGDM-------GDKGQKGSVGRHGKIGPIGSKGEKGDSGDIGP--PGPNGEPGLP 112 GP G GD+ GD G G +G G G G KGE G P PGP G PGLP Sbjct: 433 GPPGPPGDIVFRKGPPGDHGLPGYLGSPGIPGVDGPKGEPGLLCTQCPYIPGPPGLPGLP 492 Score = 54.3 bits (129), Expect = 1e-07 Identities = 37/99 (37%), Positives = 41/99 (41%), Gaps = 31/99 (31%) Query: 40 PGLKGDAGEKGDKGAP--------------------GRPGRVGPTGEKGDMGDKGQKGSV 79 PG+ G AG KG KGAP G G GP G G +G G G Sbjct: 144 PGIPGAAGLKGQKGAPAKEEDIELDAKGDPGLPGAPGPQGLPGPPGFPGPVGPPGPPGFF 203 Query: 80 GRHGKIGP-----------IGSKGEKGDSGDIGPPGPNG 107 G G +GP IG KGE+G G GPPGP G Sbjct: 204 GFPGAMGPRGPKGHMGERVIGHKGERGVKGLTGPPGPPG 242 Score = 52.8 bits (125), Expect = 3e-07 Identities = 35/84 (41%), Positives = 40/84 (47%), Gaps = 10/84 (11%) Query: 41 GLKGDAGEKGDKGAPGRPGRVGPTGEKGDMGDKGQ----KGSVGRHGKIGPIGSKGEKGD 96 GLKG G G+ G PG PG G G+ G G+KG+ +G VG G G G G KG Sbjct: 508 GLKGSPGSPGNTGLPGFPGFPGAQGDPGLKGEKGETLQPEGQVGVPGDPGLRGQPGRKGL 567 Query: 97 SGDIGPPG------PNGEPGLPCE 114 G G PG P GE L E Sbjct: 568 DGIPGTPGVKGLPGPKGELALSGE 591 Score = 52.4 bits (124), Expect = 4e-07 Identities = 32/71 (45%), Positives = 34/71 (47%) Query: 40 PGLKGDAGEKGDKGAPGRPGRVGPTGEKGDMGDKGQKGSVGRHGKIGPIGSKGEKGDSGD 99 PG G G+KG G G PG GP G G G G KG G G G GS G G G+ Sbjct: 54 PGPPGSPGQKGFTGPEGLPGPQGPKGFPGLPGLTGSKGVRGISGLPGFSGSPGLPGTPGN 113 Query: 100 IGPPGPNGEPG 110 GP G G PG Sbjct: 114 TGPYGLVGVPG 124 Score = 51.2 bits (121), Expect = 9e-07 Identities = 42/123 (34%), Positives = 52/123 (42%), Gaps = 25/123 (20%) Query: 23 GHPQPAGDDACSVQILVPGLKGDAGEKGDKGAPGRPGRVGPTGEKGDM------------ 70 G P P GD + G GD G G G+PG PG GP GE G + Sbjct: 433 GPPGPPGDI-----VFRKGPPGDHGLPGYLGSPGIPGVDGPKGEPGLLCTQCPYIPGPPG 487 Query: 71 -----GDKGQKGSVGRHGKIGPIGSKGEKGDSG---DIGPPGPNGEPGLPCECSQLRKAI 122 G G KG GR G G GS G G++G G PG G+PGL E + + Sbjct: 488 LPGLPGLHGVKGIPGRQGAAGLKGSPGSPGNTGLPGFPGFPGAQGDPGLKGEKGETLQPE 547 Query: 123 GEM 125 G++ Sbjct: 548 GQV 550 Score = 50.1 bits (118), Expect = 2e-06 Identities = 32/81 (39%), Positives = 37/81 (45%), Gaps = 1/81 (1%) Query: 33 CSVQILVPGLKGDAGEKGDKGAPGRPGRVGPTGEKGDMGDKGQKGSVGRHGKIGPIGSKG 92 C+ +PG G G G G G PGR G G KG G G G G G G G G Sbjct: 476 CTQCPYIPGPPGLPGLPGLHGVKGIPGRQGAAGLKGSPGSPGNTGLPGFPGFPGAQGDPG 535 Query: 93 EKGDSGD-IGPPGPNGEPGLP 112 KG+ G+ + P G G PG P Sbjct: 536 LKGEKGETLQPEGQVGVPGDP 556 Score = 48.5 bits (114), Expect = 6e-06 Identities = 35/82 (42%), Positives = 37/82 (45%), Gaps = 13/82 (15%) Query: 40 PGLKGD---AGEKGDKGAPGRPGRVGPT------GEKGDMGDKGQKGSVGRHGKIGPIGS 90 PGL G+ G+KGD G PG GPT EKGD G G G G G GP G Sbjct: 320 PGLMGEDGIKGQKGDIGPPGFR---GPTEYYDTYQEKGDEGTPGPPGPRGARGPQGPSGP 376 Query: 91 KGEKGDSGDIGPPGPNGEPGLP 112 G G G PG G PG P Sbjct: 377 PGVPGSPGS-SRPGLRGAPGWP 397 Score = 43.9 bits (102), Expect = 1e-04 Identities = 22/47 (46%), Positives = 25/47 (53%) Query: 66 EKGDMGDKGQKGSVGRHGKIGPIGSKGEKGDSGDIGPPGPNGEPGLP 112 +KG G KG G G GP GS G+KG +G G PGP G G P Sbjct: 35 DKGQCFCDGAKGEKGEKGFPGPPGSPGQKGFTGPEGLPGPQGPKGFP 81 Score = 33.1 bits (74), Expect = 0.26 Identities = 24/69 (34%), Positives = 29/69 (42%), Gaps = 10/69 (14%) Query: 23 GHPQPAGDDACSVQILVPGLKGDAGEKGDKGAPGRPGRVGPTGEKGDMGDKGQKGSV-GR 81 G P PAG+ G KG GE G G+ G PG G G+ G +G V R Sbjct: 1400 GTPGPAGEK---------GNKGSKGEPGPAGSDGLPGLKGKRGDSGSPATWTTRGFVFTR 1450 Query: 82 HGKIGPIGS 90 H + I S Sbjct: 1451 HSQTTAIPS 1459 >gi|73486664 alpha 1 type IX collagen isoform 2 precursor [Homo sapiens] Length = 678 Score = 80.1 bits (196), Expect = 2e-15 Identities = 44/101 (43%), Positives = 59/101 (58%), Gaps = 13/101 (12%) Query: 23 GHPQPAGDDACSVQIL-----VPGLKGDAGEKGDKGAPGRPGRVGPTGE------KGDMG 71 G P P GD +Q L +PG KG AGEKG GAPG+PG++G +G+ G++G Sbjct: 316 GKPGPPGD--AGLQGLPGVPGIPGAKGVAGEKGSTGAPGKPGQMGNSGKPGQQGPPGEVG 373 Query: 72 DKGQKGSVGRHGKIGPIGSKGEKGDSGDIGPPGPNGEPGLP 112 +G +G G G++GP+GS G G G +G PG G PG P Sbjct: 374 PRGPQGLPGSRGELGPVGSPGLPGKLGSLGSPGLPGLPGPP 414 Score = 73.6 bits (179), Expect = 2e-13 Identities = 40/84 (47%), Positives = 46/84 (54%), Gaps = 6/84 (7%) Query: 40 PGLKGDAGEKGDKGAPGRPGRVGPTGEKGDMGDKGQ------KGSVGRHGKIGPIGSKGE 93 PGL G G KG KG G PGR G GE+GD G+ G+ G+ G G G +G KGE Sbjct: 180 PGLPGMRGHKGAKGEIGEPGRQGHKGEEGDQGELGEVGAQGPPGAQGLRGITGIVGDKGE 239 Query: 94 KGDSGDIGPPGPNGEPGLPCECSQ 117 KG G G PGP G PG P + Q Sbjct: 240 KGARGLDGEPGPQGLPGAPGDQGQ 263 Score = 73.2 bits (178), Expect = 2e-13 Identities = 37/75 (49%), Positives = 40/75 (53%) Query: 40 PGLKGDAGEKGDKGAPGRPGRVGPTGEKGDMGDKGQKGSVGRHGKIGPIGSKGEKGDSGD 99 PGL G G G G PG PG G G KGD G G+ G G G G G GE+G+ GD Sbjct: 393 PGLPGKLGSLGSPGLPGLPGPPGLPGMKGDRGVVGEPGPKGEQGASGEEGEAGERGELGD 452 Query: 100 IGPPGPNGEPGLPCE 114 IG PGP G G P E Sbjct: 453 IGLPGPKGSAGNPGE 467 Score = 70.1 bits (170), Expect = 2e-12 Identities = 46/115 (40%), Positives = 55/115 (47%), Gaps = 29/115 (25%) Query: 21 PSGHPQPAGDDACSVQILVPGLKGDAGEKGDKGAPGRPGRVGPTGEKGDMGDKGQKGSVG 80 P G P P G VPG+ G G++G KG PG P GP GE G G G+ G+ G Sbjct: 33 PPGPPGPPG---------VPGIDGIDGDRGPKGPPGPP---GPAGEPGKPGAPGKPGTPG 80 Query: 81 RHGKIGP------IGSKGEKGD-----------SGDIGPPGPNGEPGLPCECSQL 118 G GP IGSKG+KG+ G GPPGP G GLP E ++ Sbjct: 81 ADGLTGPDGSPGSIGSKGQKGEPGVPGSRGFPGRGIPGPPGPPGTAGLPGELGRV 135 Score = 69.7 bits (169), Expect = 3e-12 Identities = 49/117 (41%), Positives = 57/117 (48%), Gaps = 20/117 (17%) Query: 3 GNLALVGVLISLAFLSLLPSGHPQPAGDDACSVQILVPGLKGD------AGEKGDKGAPG 56 G+ L G L SL L G P P G +PG+KGD G KG++GA G Sbjct: 391 GSPGLPGKLGSLGSPGL--PGLPGPPG---------LPGMKGDRGVVGEPGPKGEQGASG 439 Query: 57 RPGRVGPTGEKGDMGDKGQKGSVGRHGK---IGPIGSKGEKGDSGDIGPPGPNGEPG 110 G G GE GD+G G KGS G G+ GP GS+G G G GPPGP G G Sbjct: 440 EEGEAGERGELGDIGLPGPKGSAGNPGEPGLRGPEGSRGLPGVEGPRGPPGPRGVQG 496 Score = 68.9 bits (167), Expect = 4e-12 Identities = 35/70 (50%), Positives = 41/70 (58%) Query: 41 GLKGDAGEKGDKGAPGRPGRVGPTGEKGDMGDKGQKGSVGRHGKIGPIGSKGEKGDSGDI 100 G +GD GE G+ GA G PG G G G +GDKG+KG+ G G+ GP G G GD G Sbjct: 205 GEEGDQGELGEVGAQGPPGAQGLRGITGIVGDKGEKGARGLDGEPGPQGLPGAPGDQGQR 264 Query: 101 GPPGPNGEPG 110 GPPG G G Sbjct: 265 GPPGEAGPKG 274 Score = 68.6 bits (166), Expect = 6e-12 Identities = 33/75 (44%), Positives = 45/75 (60%), Gaps = 3/75 (4%) Query: 39 VPGLKGDAGEKG---DKGAPGRPGRVGPTGEKGDMGDKGQKGSVGRHGKIGPIGSKGEKG 95 +PG KG+ G+ G D G G PG G G KG G+KG G+ G+ G++G G G++G Sbjct: 308 MPGTKGEPGKPGPPGDAGLQGLPGVPGIPGAKGVAGEKGSTGAPGKPGQMGNSGKPGQQG 367 Query: 96 DSGDIGPPGPNGEPG 110 G++GP GP G PG Sbjct: 368 PPGEVGPRGPQGLPG 382 Score = 67.0 bits (162), Expect = 2e-11 Identities = 34/72 (47%), Positives = 43/72 (59%), Gaps = 3/72 (4%) Query: 41 GLKGDAGEKGDKGAPGRPGRVGPTGEKGDMGDKGQKGSVGRHGKIGPIGSKGEKGDSGDI 100 G+ G G+KG+KGA G G GP G G GD+GQ+G G+ GP G +G +G G Sbjct: 229 GITGIVGDKGEKGARGLDGEPGPQGLPGAPGDQGQRGP---PGEAGPKGDRGAEGARGIP 285 Query: 101 GPPGPNGEPGLP 112 G PGP G+ GLP Sbjct: 286 GLPGPKGDTGLP 297 Score = 67.0 bits (162), Expect = 2e-11 Identities = 37/92 (40%), Positives = 45/92 (48%) Query: 21 PSGHPQPAGDDACSVQILVPGLKGDAGEKGDKGAPGRPGRVGPTGEKGDMGDKGQKGSVG 80 P G P G+ +PG G G G G PG PG G G++G +G+ G KG G Sbjct: 377 PQGLPGSRGELGPVGSPGLPGKLGSLGSPGLPGLPGPPGLPGMKGDRGVVGEPGPKGEQG 436 Query: 81 RHGKIGPIGSKGEKGDSGDIGPPGPNGEPGLP 112 G+ G G +GE GD G GP G G PG P Sbjct: 437 ASGEEGEAGERGELGDIGLPGPKGSAGNPGEP 468 Score = 67.0 bits (162), Expect = 2e-11 Identities = 45/115 (39%), Positives = 55/115 (47%), Gaps = 23/115 (20%) Query: 21 PSGHPQPAGDDACSVQILVPGL---------------KGDAGEKGDKGAPGRPGRVGPTG 65 P G P P G++ Q+ + GL KGD GEKG++G PGR GP G Sbjct: 554 PPGPPGPPGENGFPGQMGIRGLPGIKGPPGALGLRGPKGDLGEKGERGPPGR----GPNG 609 Query: 66 EKGDMGDKGQKG--SVGRHGKIGPIGSKGEKGDSGDIGPPGPNGEPGL--PCECS 116 G +G G G S GR+G+ G G G G G GPPGP G PG P C+ Sbjct: 610 LPGAIGLPGDPGPASYGRNGRDGERGPPGVAGIPGVPGPPGPPGLPGFCEPASCT 664 Score = 66.6 bits (161), Expect = 2e-11 Identities = 43/122 (35%), Positives = 49/122 (40%), Gaps = 32/122 (26%) Query: 21 PSGHPQPAGDDACSVQILVPGLKGDAGEKGDKGAPGRPGR------VGPTGEKGDMGDKG 74 P G P G D PG G AGE G GAPG+PG GP G G +G KG Sbjct: 39 PPGVPGIDGIDGDRGPKGPPGPPGPAGEPGKPGAPGKPGTPGADGLTGPDGSPGSIGSKG 98 Query: 75 QKGSVG--------------------------RHGKIGPIGSKGEKGDSGDIGPPGPNGE 108 QKG G G++GP+G G +G G GPPGP G Sbjct: 99 QKGEPGVPGSRGFPGRGIPGPPGPPGTAGLPGELGRVGPVGDPGRRGPPGPPGPPGPRGT 158 Query: 109 PG 110 G Sbjct: 159 IG 160 Score = 66.2 bits (160), Expect = 3e-11 Identities = 36/88 (40%), Positives = 44/88 (50%), Gaps = 3/88 (3%) Query: 23 GHPQPAGDDACSVQILVPGLKGDAGEKGDKGAPGRPGRVGPTGEKGDMGDKGQKGSVGRH 82 G P P G+ S + G G+ GE GD G PG G G GE G G +G +G G Sbjct: 427 GEPGPKGEQGASGE---EGEAGERGELGDIGLPGPKGSAGNPGEPGLRGPEGSRGLPGVE 483 Query: 83 GKIGPIGSKGEKGDSGDIGPPGPNGEPG 110 G GP G +G +G+ G G PG G PG Sbjct: 484 GPRGPPGPRGVQGEQGATGLPGVQGPPG 511 Score = 65.5 bits (158), Expect = 5e-11 Identities = 32/73 (43%), Positives = 41/73 (56%) Query: 39 VPGLKGDAGEKGDKGAPGRPGRVGPTGEKGDMGDKGQKGSVGRHGKIGPIGSKGEKGDSG 98 +PG G G KGD+G G PG G G G+ G+ G++G +G G GP GS G G+ G Sbjct: 410 LPGPPGLPGMKGDRGVVGEPGPKGEQGASGEEGEAGERGELGDIGLPGPKGSAGNPGEPG 469 Query: 99 DIGPPGPNGEPGL 111 GP G G PG+ Sbjct: 470 LRGPEGSRGLPGV 482 Score = 65.1 bits (157), Expect = 6e-11 Identities = 34/74 (45%), Positives = 41/74 (55%) Query: 39 VPGLKGDAGEKGDKGAPGRPGRVGPTGEKGDMGDKGQKGSVGRHGKIGPIGSKGEKGDSG 98 +PGL G G G KG G G GP GE+G G++G+ G G G IG G KG G+ G Sbjct: 407 LPGLPGPPGLPGMKGDRGVVGEPGPKGEQGASGEEGEAGERGELGDIGLPGPKGSAGNPG 466 Query: 99 DIGPPGPNGEPGLP 112 + G GP G GLP Sbjct: 467 EPGLRGPEGSRGLP 480 Score = 63.2 bits (152), Expect = 2e-10 Identities = 40/98 (40%), Positives = 46/98 (46%), Gaps = 14/98 (14%) Query: 29 GDDACSVQILVPGLKGDAGEKGDKGAPGR--PGRVGPTGEKGDMGDKGQKGSVGRHGKIG 86 G D I G KG+ G G +G PGR PG GP G G G+ G+ G VG G+ G Sbjct: 86 GPDGSPGSIGSKGQKGEPGVPGSRGFPGRGIPGPPGPPGTAGLPGELGRVGPVGDPGRRG 145 Query: 87 PIGSKGEKGDSGDIG------------PPGPNGEPGLP 112 P G G G G IG PPG +G PGLP Sbjct: 146 PPGPPGPPGPRGTIGFHDGDPLCPNACPPGRSGYPGLP 183 Score = 63.2 bits (152), Expect = 2e-10 Identities = 35/75 (46%), Positives = 41/75 (54%), Gaps = 3/75 (4%) Query: 41 GLKGDAGEKGDKGAPGRPGRVGPTGEKGDMGDKGQKGSVGRHGKIGP---IGSKGEKGDS 97 GL G+ G +G GAPG G+ GP GE G GD+G +G+ G G GP G G G Sbjct: 244 GLDGEPGPQGLPGAPGDQGQRGPPGEAGPKGDRGAEGARGIPGLPGPKGDTGLPGVDGRD 303 Query: 98 GDIGPPGPNGEPGLP 112 G G PG GEPG P Sbjct: 304 GIPGMPGTKGEPGKP 318 Score = 61.2 bits (147), Expect = 9e-10 Identities = 34/71 (47%), Positives = 40/71 (56%), Gaps = 5/71 (7%) Query: 45 DAGEKGDKGAPGRPGRVGPTGEKG---DMGDKGQKGSVGRHGKIGPIGSKGEKGDSGDIG 101 D+G G G PG PG GP GE G MG +G G G G +G G KG+ G+ G+ G Sbjct: 542 DSGATGLPGRPGPPGPPGPPGENGFPGQMGIRGLPGIKGPPGALGLRGPKGDLGEKGERG 601 Query: 102 PP--GPNGEPG 110 PP GPNG PG Sbjct: 602 PPGRGPNGLPG 612 Score = 60.8 bits (146), Expect = 1e-09 Identities = 33/80 (41%), Positives = 42/80 (52%), Gaps = 6/80 (7%) Query: 39 VPGLKGDAGEKGDKGAPGRPG------RVGPTGEKGDMGDKGQKGSVGRHGKIGPIGSKG 92 + G+ GD GEKG +G G PG G G++G G+ G KG G G G G G Sbjct: 230 ITGIVGDKGEKGARGLDGEPGPQGLPGAPGDQGQRGPPGEAGPKGDRGAEGARGIPGLPG 289 Query: 93 EKGDSGDIGPPGPNGEPGLP 112 KGD+G G G +G PG+P Sbjct: 290 PKGDTGLPGVDGRDGIPGMP 309 Score = 60.1 bits (144), Expect = 2e-09 Identities = 38/92 (41%), Positives = 42/92 (45%), Gaps = 6/92 (6%) Query: 21 PSGHPQPAGDDACSVQILVPGLKGDAGEKGDKGAPGRPGRVGPTGEKGDMGDKGQKGSVG 80 P G P GD G G+AG KGD+GA G G G G KGD G G G G Sbjct: 251 PQGLPGAPGDQGQR------GPPGEAGPKGDRGAEGARGIPGLPGPKGDTGLPGVDGRDG 304 Query: 81 RHGKIGPIGSKGEKGDSGDIGPPGPNGEPGLP 112 G G G G+ G GD G G G PG+P Sbjct: 305 IPGMPGTKGEPGKPGPPGDAGLQGLPGVPGIP 336 Score = 59.3 bits (142), Expect = 3e-09 Identities = 34/82 (41%), Positives = 40/82 (48%), Gaps = 9/82 (10%) Query: 40 PGLKGDAGEKGDKGAPGRPGRVGPTGEKGD---------MGDKGQKGSVGRHGKIGPIGS 90 PG +G G GD+G G PG GP G++G G KG G G G+ G G Sbjct: 249 PGPQGLPGAPGDQGQRGPPGEAGPKGDRGAEGARGIPGLPGPKGDTGLPGVDGRDGIPGM 308 Query: 91 KGEKGDSGDIGPPGPNGEPGLP 112 G KG+ G GPPG G GLP Sbjct: 309 PGTKGEPGKPGPPGDAGLQGLP 330 Score = 58.2 bits (139), Expect = 8e-09 Identities = 36/110 (32%), Positives = 47/110 (42%), Gaps = 21/110 (19%) Query: 23 GHPQPAGDDACSVQILVPGLKGDAGEKGDKGAPGRPG---------------------RV 61 G P P G ++ G GD G +G G PG PG R Sbjct: 118 GPPGPPGTAGLPGELGRVGPVGDPGRRGPPGPPGPPGPRGTIGFHDGDPLCPNACPPGRS 177 Query: 62 GPTGEKGDMGDKGQKGSVGRHGKIGPIGSKGEKGDSGDIGPPGPNGEPGL 111 G G G G KG KG +G G+ G G +G++G+ G++G GP G GL Sbjct: 178 GYPGLPGMRGHKGAKGEIGEPGRQGHKGEEGDQGELGEVGAQGPPGAQGL 227 Score = 57.8 bits (138), Expect = 1e-08 Identities = 30/68 (44%), Positives = 36/68 (52%) Query: 43 KGDAGEKGDKGAPGRPGRVGPTGEKGDMGDKGQKGSVGRHGKIGPIGSKGEKGDSGDIGP 102 +G GE+G G PG PG G G GD G KG G G G+ G G+ G+ G G G Sbjct: 25 RGPPGEQGPPGPPGPPGVPGIDGIDGDRGPKGPPGPPGPAGEPGKPGAPGKPGTPGADGL 84 Query: 103 PGPNGEPG 110 GP+G PG Sbjct: 85 TGPDGSPG 92 Score = 54.3 bits (129), Expect = 1e-07 Identities = 36/99 (36%), Positives = 46/99 (46%), Gaps = 25/99 (25%) Query: 39 VPGLKGDAGEKGDKGAPGRPGR---------------VGPTGEKGDMGDKGQKGSVGR-- 81 +PG G G G G G PG+ +G G KGD+G+KG++G GR Sbjct: 548 LPGRPGPPGPPGPPGENGFPGQMGIRGLPGIKGPPGALGLRGPKGDLGEKGERGPPGRGP 607 Query: 82 HGKIGPIG--------SKGEKGDSGDIGPPGPNGEPGLP 112 +G G IG S G G G+ GPPG G PG+P Sbjct: 608 NGLPGAIGLPGDPGPASYGRNGRDGERGPPGVAGIPGVP 646 Score = 52.0 bits (123), Expect = 5e-07 Identities = 40/130 (30%), Positives = 50/130 (38%), Gaps = 39/130 (30%) Query: 22 SGHPQPAGDDACSVQILVPGLKGDAGEKGD------KGAPGRPGRVGPTGEKGDMGDKGQ 75 SG AG+ I +PG KG AG G+ +G+ G PG GP G G G +G+ Sbjct: 438 SGEEGEAGERGELGDIGLPGPKGSAGNPGEPGLRGPEGSRGLPGVEGPRGPPGPRGVQGE 497 Query: 76 KGSVGRHGKIGP---------------------------------IGSKGEKGDSGDIGP 102 +G+ G G GP G+ G G G GP Sbjct: 498 QGATGLPGVQGPPGRAPTDQHIKQVCMRVIQEHFAEMAASLKRPDSGATGLPGRPGPPGP 557 Query: 103 PGPNGEPGLP 112 PGP GE G P Sbjct: 558 PGPPGENGFP 567 Score = 41.2 bits (95), Expect = 0.001 Identities = 31/105 (29%), Positives = 37/105 (35%), Gaps = 33/105 (31%) Query: 39 VPGLKGDAGEKGDKGAPGRPGRVGPTGEKGDMG--------------------------- 71 +PG++G G G +G G G G G +G G Sbjct: 479 LPGVEGPRGPPGPRGVQGEQGATGLPGVQGPPGRAPTDQHIKQVCMRVIQEHFAEMAASL 538 Query: 72 ---DKGQKGSVGRHGKIGPIGSKGEKGDSGDI---GPPGPNGEPG 110 D G G GR G GP G GE G G + G PG G PG Sbjct: 539 KRPDSGATGLPGRPGPPGPPGPPGENGFPGQMGIRGLPGIKGPPG 583 >gi|29725624 collagen, type XXIII, alpha 1 [Homo sapiens] Length = 540 Score = 80.1 bits (196), Expect = 2e-15 Identities = 40/90 (44%), Positives = 48/90 (53%), Gaps = 6/90 (6%) Query: 23 GHPQPAGDDACSVQILVPGLKGDAGEKGDKGAPGRPGRVGPTGEKGDMGDKGQKGSVGRH 82 G P P G+ PG G G++G GA G PG GP G +G GD G+ G G Sbjct: 157 GLPGPKGEKGA------PGDFGPRGDQGQDGAAGPPGPPGPPGARGPPGDTGKDGPRGAQ 210 Query: 83 GKIGPIGSKGEKGDSGDIGPPGPNGEPGLP 112 G GP G G+ G+ G GPPGP GEPG+P Sbjct: 211 GPAGPKGEPGQDGEMGPKGPPGPKGEPGVP 240 Score = 72.4 bits (176), Expect = 4e-13 Identities = 44/95 (46%), Positives = 50/95 (52%), Gaps = 13/95 (13%) Query: 21 PSGHPQPAGDDACSVQILVPGLKGDAGEKGDKGAPGRPGR---VGPTGEKGDMGDKGQKG 77 PSG P P G PGL G G KG+KG PG PG GP GEKGD ++G+KG Sbjct: 449 PSGLPGPVGP---------PGLIGLPGTKGEKGRPGEPGLDGFPGPRGEKGDRSERGEKG 499 Query: 78 SVGRHGKIGPIGSKGEKGDSGDIGPPGPNGEPGLP 112 G G+ G G KGE G G + P P G GLP Sbjct: 500 ERGVPGRKGVKGQKGEPGPPG-LDQPCPVGPDGLP 533 Score = 70.1 bits (170), Expect = 2e-12 Identities = 37/89 (41%), Positives = 43/89 (48%), Gaps = 9/89 (10%) Query: 22 SGHPQPAGDDACSVQILVPGLKGDAGEKGDKGAPGRPGRVGPTGEKGDMGDKGQKGSVGR 81 +G P P G PG +G G+ G G G G GP GE G G+ G KG G Sbjct: 183 AGPPGPPGP---------PGARGPPGDTGKDGPRGAQGPAGPKGEPGQDGEMGPKGPPGP 233 Query: 82 HGKIGPIGSKGEKGDSGDIGPPGPNGEPG 110 G+ G G KG+ G GPPGP GEPG Sbjct: 234 KGEPGVPGKKGDDGTPSQPGPPGPKGEPG 262 Score = 69.3 bits (168), Expect = 3e-12 Identities = 41/103 (39%), Positives = 48/103 (46%), Gaps = 19/103 (18%) Query: 21 PSGHPQPAGDDACSVQILVPGLKGDAGEKGDKGAPGRPGRVGPTGEKGDMGDKGQKGSVG 80 P G P P G ++ +PG G GEKG KG G PG GP G KG+ G+ G G G Sbjct: 325 PQGPPGPPGIPGAKGELGLPGAPGIDGEKGPKGQKGDPGEPGPAGLKGEAGEMGLSGLPG 384 Query: 81 RHGKIGPIGSKGEKGDSG-------------DIGPPGPNGEPG 110 G KGEKG+S + GPPGP G PG Sbjct: 385 AD------GLKGEKGESASDSLQESLAQLIVEPGPPGPPGPPG 421 Score = 68.9 bits (167), Expect = 4e-12 Identities = 38/90 (42%), Positives = 45/90 (50%) Query: 21 PSGHPQPAGDDACSVQILVPGLKGDAGEKGDKGAPGRPGRVGPTGEKGDMGDKGQKGSVG 80 P G P P G + G KG+ G G++G G PG VGP G G G KG+KG G Sbjct: 416 PPGPPGPMGLQGIQGPKGLDGAKGEKGASGERGPSGLPGPVGPPGLIGLPGTKGEKGRPG 475 Query: 81 RHGKIGPIGSKGEKGDSGDIGPPGPNGEPG 110 G G G +GEKGD + G G G PG Sbjct: 476 EPGLDGFPGPRGEKGDRSERGEKGERGVPG 505 Score = 68.2 bits (165), Expect = 7e-12 Identities = 44/118 (37%), Positives = 51/118 (43%), Gaps = 38/118 (32%) Query: 21 PSGHPQPAGDDACSVQILVPGLKGDAGEKGDKGAPGRPGRVGPTGEKGDM---------- 70 P G P P G+ PG+ G +KGD G P +PG GP GE G M Sbjct: 227 PKGPPGPKGE---------PGVPG---KKGDDGTPSQPGPPGPKGEPGSMGPRGENGVDG 274 Query: 71 --GDKGQKGSVGRHGKIGPIGSKGEKGDSGDI--------------GPPGPNGEPGLP 112 G KG+ G G G GP G+ G KG+ GD GPPGP G PG P Sbjct: 275 APGPKGEPGHRGTDGAAGPRGAPGLKGEQGDTVVIDYDGRILDALKGPPGPQGPPGPP 332 Score = 67.8 bits (164), Expect = 1e-11 Identities = 35/76 (46%), Positives = 41/76 (53%), Gaps = 3/76 (3%) Query: 40 PGLKGDAGEKGDKGAPGRPGR---VGPTGEKGDMGDKGQKGSVGRHGKIGPIGSKGEKGD 96 PG +G G +GD G PG+ GR GP G G G G KG G G GP G +G+ G Sbjct: 123 PGRRGKPGRRGDPGPPGQSGRDGYPGPLGLDGKPGLPGPKGEKGAPGDFGPRGDQGQDGA 182 Query: 97 SGDIGPPGPNGEPGLP 112 +G GPPGP G G P Sbjct: 183 AGPPGPPGPPGARGPP 198 Score = 67.8 bits (164), Expect = 1e-11 Identities = 39/96 (40%), Positives = 49/96 (51%), Gaps = 6/96 (6%) Query: 21 PSGHPQPAGDDACSVQILVPGLKGDAGEKGDKGAPGRPGRVGPTGEKGDMGDKGQKGSVG 80 P G P G + + G +G AG KG+ G G G GP G KG+ G G+KG G Sbjct: 188 PPGPPGARGPPGDTGKDGPRGAQGPAGPKGEPGQDGEMGPKGPPGPKGEPGVPGKKGDDG 247 Query: 81 RHGKIGPIGSKGE------KGDSGDIGPPGPNGEPG 110 + GP G KGE +G++G G PGP GEPG Sbjct: 248 TPSQPGPPGPKGEPGSMGPRGENGVDGAPGPKGEPG 283 Score = 66.2 bits (160), Expect = 3e-11 Identities = 37/88 (42%), Positives = 40/88 (45%) Query: 23 GHPQPAGDDACSVQILVPGLKGDAGEKGDKGAPGRPGRVGPTGEKGDMGDKGQKGSVGRH 82 G P P G GL G G G KG G PG GP G++G G G G G Sbjct: 133 GDPGPPGQSGRDGYPGPLGLDGKPGLPGPKGEKGAPGDFGPRGDQGQDGAAGPPGPPGPP 192 Query: 83 GKIGPIGSKGEKGDSGDIGPPGPNGEPG 110 G GP G G+ G G GP GP GEPG Sbjct: 193 GARGPPGDTGKDGPRGAQGPAGPKGEPG 220 Score = 65.1 bits (157), Expect = 6e-11 Identities = 39/94 (41%), Positives = 44/94 (46%), Gaps = 3/94 (3%) Query: 21 PSGHPQPAGDDACSVQILVPGLKGDAGEKGDKGAPGRPGRVGPTGEKGDMGDKGQKGSVG 80 P+G G D PG KG+ G G KG G P + GP G KG+ G G +G G Sbjct: 212 PAGPKGEPGQDGEMGPKGPPGPKGEPGVPGKKGDDGTPSQPGPPGPKGEPGSMGPRGENG 271 Query: 81 RHGKIGPIGSKGEKGDSGDIGPPGPNGEPGLPCE 114 G GP KGE G G G GP G PGL E Sbjct: 272 VDGAPGP---KGEPGHRGTDGAAGPRGAPGLKGE 302 Score = 62.8 bits (151), Expect = 3e-10 Identities = 41/113 (36%), Positives = 50/113 (44%), Gaps = 23/113 (20%) Query: 21 PSGHPQPAGDDACSVQILVPGLKGDAGE--------------KGDKGAPGRPGRVGPTGE 66 P G P G D + PGLKG+ G+ KG G G PG G G Sbjct: 278 PKGEPGHRGTDGAAGPRGAPGLKGEQGDTVVIDYDGRILDALKGPPGPQGPPGPPGIPGA 337 Query: 67 KGDMG---------DKGQKGSVGRHGKIGPIGSKGEKGDSGDIGPPGPNGEPG 110 KG++G +KG KG G G+ GP G KGE G+ G G PG +G G Sbjct: 338 KGELGLPGAPGIDGEKGPKGQKGDPGEPGPAGLKGEAGEMGLSGLPGADGLKG 390 Score = 60.5 bits (145), Expect = 2e-09 Identities = 43/114 (37%), Positives = 50/114 (43%), Gaps = 22/114 (19%) Query: 23 GHPQPAGDDACSVQILVPGLKGDAGEKGDKGA-------------------PGRPGRVGP 63 G P PAG + ++ + GL G G KG+KG PG PG GP Sbjct: 363 GEPGPAGLKGEAGEMGLSGLPGADGLKGEKGESASDSLQESLAQLIVEPGPPGPPGPPGP 422 Query: 64 TGEKGDMGDKG---QKGSVGRHGKIGPIGSKGEKGDSGDIGPPGPNGEPGLPCE 114 G +G G KG KG G G+ GP G G G G IG PG GE G P E Sbjct: 423 MGLQGIQGPKGLDGAKGEKGASGERGPSGLPGPVGPPGLIGLPGTKGEKGRPGE 476 Score = 56.6 bits (135), Expect = 2e-08 Identities = 32/77 (41%), Positives = 39/77 (50%), Gaps = 3/77 (3%) Query: 37 ILVPGLKGDAGEKGDKGAPGRPGRVGPTGEKGDMGDKGQKGSVGRHGKIGP---IGSKGE 93 I+ PG G G G G G G G G KG+ G G++G G G +GP IG G Sbjct: 408 IVEPGPPGPPGPPGPMGLQGIQGPKGLDGAKGEKGASGERGPSGLPGPVGPPGLIGLPGT 467 Query: 94 KGDSGDIGPPGPNGEPG 110 KG+ G G PG +G PG Sbjct: 468 KGEKGRPGEPGLDGFPG 484 >gi|148536825 alpha 1 type IV collagen preproprotein [Homo sapiens] Length = 1669 Score = 79.7 bits (195), Expect = 2e-15 Identities = 44/91 (48%), Positives = 50/91 (54%), Gaps = 1/91 (1%) Query: 22 SGHPQPAGDDACSVQILVPGLKGDAGEKGDKGAPGRPGRVGPTGEKGDMGDKGQKGSVGR 81 +G P G + Q PG G G G+KG PG PGR P G G GDKG KG VG Sbjct: 1135 AGLPGTPGPTGPAGQKGEPGSDGIPGSAGEKGEPGLPGRGFP-GFPGAKGDKGSKGEVGF 1193 Query: 82 HGKIGPIGSKGEKGDSGDIGPPGPNGEPGLP 112 G G G G KG+ G +GPPGP G+PGLP Sbjct: 1194 PGLAGSPGIPGSKGEQGFMGPPGPQGQPGLP 1224 Score = 77.4 bits (189), Expect = 1e-14 Identities = 44/96 (45%), Positives = 50/96 (52%), Gaps = 15/96 (15%) Query: 23 GHPQPAGDDACSVQILVPGLKGDAGEKGDKGAPGRPGRVGPTGEKGDMGDKGQKGSVGRH 82 G P P G PG GD GEKG G PG PG G G +G G+KG+ G G Sbjct: 281 GKPGPRGK---------PGKDGDKGEKGSPGFPGEPGYPGLIGRQGPQGEKGEAGPPGPP 331 Query: 83 GKI---GPIGSKGEKGDSGDIGP---PGPNGEPGLP 112 G + GP+G KGE+G G GP PGP G PGLP Sbjct: 332 GIVIGTGPLGEKGERGYPGTPGPRGEPGPKGFPGLP 367 Score = 76.6 bits (187), Expect = 2e-14 Identities = 41/74 (55%), Positives = 48/74 (64%), Gaps = 8/74 (10%) Query: 40 PGLKGDAGEKGDKGAPGRPGRVGPTGEKGDMGD-KGQKGSVGRHGKIGPIGSKGEKGDSG 98 PGLKGD KGD G PG+PG + +K DMG KGQKG G G+IGPIG KG +GD G Sbjct: 920 PGLKGD---KGDVGLPGKPGSM----DKVDMGSMKGQKGDQGEKGQIGPIGEKGSRGDPG 972 Query: 99 DIGPPGPNGEPGLP 112 G PG +G+ G P Sbjct: 973 TPGVPGKDGQAGQP 986 Score = 73.6 bits (179), Expect = 2e-13 Identities = 42/100 (42%), Positives = 48/100 (48%), Gaps = 9/100 (9%) Query: 22 SGHPQPAGDDACSVQILVPGLKGDAGEKGDKGAPGRPGRVGPTGEKGDM---------GD 72 +G P G+ I +PG+ G G KG G+ G PG G GEKGD G Sbjct: 1072 AGFPGSPGEKGEKGSIGIPGMPGSPGLKGSPGSVGYPGSPGLPGEKGDKGLPGLDGIPGV 1131 Query: 73 KGQKGSVGRHGKIGPIGSKGEKGDSGDIGPPGPNGEPGLP 112 KG+ G G G GP G KGE G G G G GEPGLP Sbjct: 1132 KGEAGLPGTPGPTGPAGQKGEPGSDGIPGSAGEKGEPGLP 1171 Score = 72.4 bits (176), Expect = 4e-13 Identities = 42/98 (42%), Positives = 49/98 (50%), Gaps = 10/98 (10%) Query: 22 SGHPQPAGDDACSVQILVPGLKGDAGE-------KGDKGAPGRPGRVGPTGEKGDMGDKG 74 +G P P G Q PG KG+ GE KGDKG PG PG+ G TG G G G Sbjct: 509 AGVPGPQGTPGLIGQ---PGAKGEPGEFYFDLRLKGDKGDPGFPGQPGMTGRAGSPGRDG 565 Query: 75 QKGSVGRHGKIGPIGSKGEKGDSGDIGPPGPNGEPGLP 112 G G G G +G KGE+G G +G PG G+ G P Sbjct: 566 HPGLPGPKGSPGSVGLKGERGPPGGVGFPGSRGDTGPP 603 Score = 68.9 bits (167), Expect = 4e-12 Identities = 38/87 (43%), Positives = 44/87 (50%), Gaps = 3/87 (3%) Query: 25 PQPAGDDACSVQILVPGLKGDAGEKGDKGAPGRPGRVGPTGEKGDMGDKGQKGSVGRHGK 84 P P GD +PG+ G +G G G G PG G G KG+MG G G G G Sbjct: 839 PGPKGDKGAQG---LPGITGQSGLPGLPGQQGAPGIPGFPGSKGEMGVMGTPGQPGSPGP 895 Query: 85 IGPIGSKGEKGDSGDIGPPGPNGEPGL 111 +G G GEKGD G G GP G+PGL Sbjct: 896 VGAPGLPGEKGDHGFPGSSGPRGDPGL 922 Score = 68.6 bits (166), Expect = 6e-12 Identities = 33/68 (48%), Positives = 42/68 (61%), Gaps = 1/68 (1%) Query: 40 PGLKGDAGEKGDKGAPGRPGRVGPTGEKGDMGDKGQKGSVGRHGKIGPIGSKGEKGDSGD 99 PG +G G G+KG PG+PG G G+ GD G+KG G G G G IG +G +G+ G+ Sbjct: 266 PGFQGMPGV-GEKGEPGKPGPRGKPGKDGDKGEKGSPGFPGEPGYPGLIGRQGPQGEKGE 324 Query: 100 IGPPGPNG 107 GPPGP G Sbjct: 325 AGPPGPPG 332 Score = 67.8 bits (164), Expect = 1e-11 Identities = 43/106 (40%), Positives = 51/106 (48%), Gaps = 14/106 (13%) Query: 21 PSGHPQPAGDDACSVQ--------ILVPGLKGDAGEKGDKGAPGRPGR------VGPTGE 66 P G P GD + I +PGL+G+ G++G G PG PG +G G Sbjct: 1033 PQGSPGLPGDKGAKGEKGQAGPPGIGIPGLRGEKGDQGIAGFPGSPGEKGEKGSIGIPGM 1092 Query: 67 KGDMGDKGQKGSVGRHGKIGPIGSKGEKGDSGDIGPPGPNGEPGLP 112 G G KG GSVG G G G KG+KG G G PG GE GLP Sbjct: 1093 PGSPGLKGSPGSVGYPGSPGLPGEKGDKGLPGLDGIPGVKGEAGLP 1138 Score = 67.0 bits (162), Expect = 2e-11 Identities = 46/120 (38%), Positives = 53/120 (44%), Gaps = 33/120 (27%) Query: 23 GHPQPAGDDACSVQILVPGLKGDAGEKGDKGAPGR--------------PGRVGPTGEKG 68 G P P G Q PG G+ GEKGD+G PG PG GP G+ G Sbjct: 368 GQPGPPGLPVPG-QAGAPGFPGERGEKGDRGFPGTSLPGPSGRDGLPGPPGSPGPPGQPG 426 Query: 69 -----------DMGDKGQKGSVGRHGKIGPIGSKGEKGDS-------GDIGPPGPNGEPG 110 GD+G G G+ G IG IG KG+KG+S G GPPGP G PG Sbjct: 427 YTNGIVECQPGPPGDQGPPGIPGQPGFIGEIGEKGQKGESCLICDIDGYRGPPGPQGPPG 486 Score = 66.6 bits (161), Expect = 2e-11 Identities = 38/90 (42%), Positives = 44/90 (48%), Gaps = 6/90 (6%) Query: 29 GDDACSVQILVPGLKGDAGEKGDKGAPGRPGRVGPTGEKGDMGDKGQKGSVGRHGKIGPI 88 GD QI G KG G+ G G PG+ G+ G G+ G GD G G+ G G GP Sbjct: 951 GDQGEKGQIGPIGEKGSRGDPGTPGVPGKDGQAGQPGQPGPKGDPGISGTPGAPGLPGPK 1010 Query: 89 GS------KGEKGDSGDIGPPGPNGEPGLP 112 GS G G+ G G PGP G PGLP Sbjct: 1011 GSVGGMGLPGTPGEKGVPGIPGPQGSPGLP 1040 Score = 65.9 bits (159), Expect = 4e-11 Identities = 43/103 (41%), Positives = 53/103 (51%), Gaps = 12/103 (11%) Query: 21 PSGHPQPAGDDACSVQILVPGLKGDAGEKGDKGAPGRPGRVGPTGEKGDM---GDKGQKG 77 P G P P G+ + + G KGD G++G G PG PG+ EKGD G+KGQKG Sbjct: 207 PPGPPGPPGEKG-QMGLSFQGPKGDKGDQGVSGPPGVPGQA-QVQEKGDFATKGEKGQKG 264 Query: 78 SVGRHGKIGPIGSKGEKGDSGDIGPPGPNGE------PGLPCE 114 G G G +G KGE G G G PG +G+ PG P E Sbjct: 265 EPGFQGMPG-VGEKGEPGKPGPRGKPGKDGDKGEKGSPGFPGE 306 Score = 65.9 bits (159), Expect = 4e-11 Identities = 35/69 (50%), Positives = 37/69 (53%), Gaps = 3/69 (4%) Query: 42 LKGDAGEKGDKGAPGRPGRVGPTGEKGD---MGDKGQKGSVGRHGKIGPIGSKGEKGDSG 98 LKGD G+ G G PG GR G G G G KG GSVG G+ GP G G G G Sbjct: 539 LKGDKGDPGFPGQPGMTGRAGSPGRDGHPGLPGPKGSPGSVGLKGERGPPGGVGFPGSRG 598 Query: 99 DIGPPGPNG 107 D GPPGP G Sbjct: 599 DTGPPGPPG 607 Score = 65.5 bits (158), Expect = 5e-11 Identities = 42/109 (38%), Positives = 50/109 (45%), Gaps = 27/109 (24%) Query: 22 SGHPQPAGDDACSVQILVPGLKGDAGE----------KGDKGAPGRPGRVGPTGEKGDMG 71 +G+P P G +PG+KGD GE KG++G PG PG GP G G G Sbjct: 144 AGNPGPPG---------LPGMKGDPGEILGHVPGMLLKGERGFPGIPGTPGPPGLPGLQG 194 Query: 72 DKGQKGSVGRHGKIGPIGSKGEKGD--------SGDIGPPGPNGEPGLP 112 G G G G GP G GEKG GD G G +G PG+P Sbjct: 195 PVGPPGFTGPPGPPGPPGPPGEKGQMGLSFQGPKGDKGDQGVSGPPGVP 243 Score = 65.5 bits (158), Expect = 5e-11 Identities = 33/69 (47%), Positives = 37/69 (53%), Gaps = 3/69 (4%) Query: 39 VPGLKGDAGEKGDKGAPGRPGRVGPTGEKGDMGDKGQKGSVGRHGKIGPIGSKGEKGDSG 98 +PG G GE G G PG+PG GP G G G+KG G G G P G G KGD G Sbjct: 871 IPGFPGSKGEMGVMGTPGQPGSPGPVGAPGLPGEKGDHGFPGSSG---PRGDPGLKGDKG 927 Query: 99 DIGPPGPNG 107 D+G PG G Sbjct: 928 DVGLPGKPG 936 Score = 65.5 bits (158), Expect = 5e-11 Identities = 39/86 (45%), Positives = 44/86 (51%), Gaps = 13/86 (15%) Query: 40 PGLKGDAGEKGDKGAPGRPGRVGPTGEKGDMGDKGQKGSVGRHGKIGPIGSKGEKGDS-- 97 PG+ G G+ G +G PG G G TG KGDMG G G G G G G KG++GD Sbjct: 1277 PGVPGPKGDPGFQGMPGIGGSPGITGSKGDMGPPGVPGFQGPKGLPGLQGIKGDQGDQGV 1336 Query: 98 -------GDIGPPGP----NGEPGLP 112 G GPPGP GEPGLP Sbjct: 1337 PGAKGLPGPPGPPGPYDIIKGEPGLP 1362 Score = 65.1 bits (157), Expect = 6e-11 Identities = 37/94 (39%), Positives = 45/94 (47%) Query: 21 PSGHPQPAGDDACSVQILVPGLKGDAGEKGDKGAPGRPGRVGPTGEKGDMGDKGQKGSVG 80 P G P G + + +PG KG G G G PG PG G G+ G G G G G Sbjct: 68 PEGPQGPPGQKGDTGEPGLPGTKGTRGPPGASGYPGNPGLPGIPGQDGPPGPPGIPGCNG 127 Query: 81 RHGKIGPIGSKGEKGDSGDIGPPGPNGEPGLPCE 114 G+ GP+G G G +G+ GPPG G G P E Sbjct: 128 TKGERGPLGPPGLPGFAGNPGPPGLPGMKGDPGE 161 Score = 65.1 bits (157), Expect = 6e-11 Identities = 35/72 (48%), Positives = 40/72 (55%), Gaps = 7/72 (9%) Query: 39 VPGLKGDAGEKGDKGAPGRPGRVGPTGEKGDMGDKGQKGSVGRHGKIGPIGSKGEKGDSG 98 +PG G G +GD+G PG PGR G GEKG +G G G GP G KG G G Sbjct: 653 LPGSPGFPGPQGDRGFPGTPGRPGLPGEKGAVGQPG-------IGFPGPPGPKGVDGLPG 705 Query: 99 DIGPPGPNGEPG 110 D+GPPG G PG Sbjct: 706 DMGPPGTPGRPG 717 Score = 65.1 bits (157), Expect = 6e-11 Identities = 40/104 (38%), Positives = 46/104 (44%), Gaps = 14/104 (13%) Query: 23 GHPQPAGDDACSVQILVPGLKGDAGEKGDKGAPGRPGRVGPTGE--------------KG 68 G P GD ++ PGL G G G KG G G GP G+ KG Sbjct: 1177 GFPGAKGDKGSKGEVGFPGLAGSPGIPGSKGEQGFMGPPGPQGQPGLPGSPGHATEGPKG 1236 Query: 69 DMGDKGQKGSVGRHGKIGPIGSKGEKGDSGDIGPPGPNGEPGLP 112 D G +GQ G G G +GP G G G GD G PG G PG+P Sbjct: 1237 DRGPQGQPGLPGLPGPMGPPGLPGIDGVKGDKGNPGWPGAPGVP 1280 Score = 64.7 bits (156), Expect = 8e-11 Identities = 40/80 (50%), Positives = 42/80 (52%), Gaps = 5/80 (6%) Query: 40 PGLKGDAGEKGDKGAPGRPGR--VGPTGEKGDMGDKGQKGSVGRHGKIGPIGSKGEKGDS 97 PGL GD G KG+KG G PG G GEKGD G G GS G G+ G IG G G Sbjct: 1037 PGLPGDKGAKGEKGQAGPPGIGIPGLRGEKGDQGIAGFPGSPGEKGEKGSIGIPGMPGSP 1096 Query: 98 GDIGPPGP---NGEPGLPCE 114 G G PG G PGLP E Sbjct: 1097 GLKGSPGSVGYPGSPGLPGE 1116 Score = 64.3 bits (155), Expect = 1e-10 Identities = 36/78 (46%), Positives = 43/78 (55%), Gaps = 8/78 (10%) Query: 40 PGLKGDAGEKGD-----KGAPGRPGRVGPTGEKGDMGDKGQKGSVGRHGKIGPIGSKGEK 94 PG++G GE G KG PG PG G GEKG + G G G HG IGP G +G + Sbjct: 725 PGVQGQKGEPGVGLPGLKGLPGLPGIPGTPGEKGSI---GVPGVPGEHGAIGPPGLQGIR 781 Query: 95 GDSGDIGPPGPNGEPGLP 112 G+ G G PG G PG+P Sbjct: 782 GEPGPPGLPGSVGSPGVP 799 Score = 64.3 bits (155), Expect = 1e-10 Identities = 34/81 (41%), Positives = 42/81 (51%), Gaps = 5/81 (6%) Query: 39 VPGLKGDAGEKGDKGAPGRPGRVGPTGEKGDMGDKGQKGSVGRHGKIGP-----IGSKGE 93 +PG+ G GEKG G PG PG G G G G +G+ G G G +G IG G Sbjct: 747 LPGIPGTPGEKGSIGVPGVPGEHGAIGPPGLQGIRGEPGPPGLPGSVGSPGVPGIGPPGA 806 Query: 94 KGDSGDIGPPGPNGEPGLPCE 114 +G G GPPG +G PG+ E Sbjct: 807 RGPPGGQGPPGLSGPPGIKGE 827 Score = 63.9 bits (154), Expect = 1e-10 Identities = 36/75 (48%), Positives = 40/75 (53%), Gaps = 7/75 (9%) Query: 39 VPGLKGDAGEKGDKGAPGRPGRVGPTGEKGDMGDKGQKGSVGRHGKIGPIGSKGEKG--- 95 +PG KG G G KG G PG VG G +GD G G G +G GPIG KG+ G Sbjct: 569 LPGPKGSPGSVGLKGERGPPGGVGFPGSRGDTGPPGPPG----YGPAGPIGDKGQAGFPG 624 Query: 96 DSGDIGPPGPNGEPG 110 G G PGP GEPG Sbjct: 625 GPGSPGLPGPKGEPG 639 Score = 63.9 bits (154), Expect = 1e-10 Identities = 39/99 (39%), Positives = 47/99 (47%), Gaps = 15/99 (15%) Query: 21 PSGHPQPAGDDACSVQILVPGLKGDA---------GEKGDKGAPGRPGRVGPTGEKGDMG 71 P G P GD + +PG G G+KGD+ G G++GP GEKG G Sbjct: 916 PRGDPGLKGDKG---DVGLPGKPGSMDKVDMGSMKGQKGDQ---GEKGQIGPIGEKGSRG 969 Query: 72 DKGQKGSVGRHGKIGPIGSKGEKGDSGDIGPPGPNGEPG 110 D G G G+ G+ G G G KGD G G PG G PG Sbjct: 970 DPGTPGVPGKDGQAGQPGQPGPKGDPGISGTPGAPGLPG 1008 Score = 63.9 bits (154), Expect = 1e-10 Identities = 40/91 (43%), Positives = 41/91 (45%), Gaps = 18/91 (19%) Query: 40 PGLKGDAGEKGDKGAPGRPGRVGPTGEKGD------------------MGDKGQKGSVGR 81 PGL G G KGDKG PG PG G G KGD GD G G G Sbjct: 1256 PGLPGIDGVKGDKGNPGWPGAPGVPGPKGDPGFQGMPGIGGSPGITGSKGDMGPPGVPGF 1315 Query: 82 HGKIGPIGSKGEKGDSGDIGPPGPNGEPGLP 112 G G G +G KGD GD G PG G PG P Sbjct: 1316 QGPKGLPGLQGIKGDQGDQGVPGAKGLPGPP 1346 Score = 63.5 bits (153), Expect = 2e-10 Identities = 40/96 (41%), Positives = 43/96 (44%), Gaps = 10/96 (10%) Query: 25 PQPAGDDACSVQILVPGLKGDAGEKGDKGAP----------GRPGRVGPTGEKGDMGDKG 74 P P GD PG G+ GEKG KG G PG GP GE G G G Sbjct: 436 PGPPGDQGPPGIPGQPGFIGEIGEKGQKGESCLICDIDGYRGPPGPQGPPGEIGFPGQPG 495 Query: 75 QKGSVGRHGKIGPIGSKGEKGDSGDIGPPGPNGEPG 110 KG G G+ G G G +G G IG PG GEPG Sbjct: 496 AKGDRGLPGRDGVAGVPGPQGTPGLIGQPGAKGEPG 531 Score = 63.5 bits (153), Expect = 2e-10 Identities = 40/92 (43%), Positives = 46/92 (50%), Gaps = 3/92 (3%) Query: 23 GHPQPAGDDACSVQILVPGLKGDAGEKGDKGA--PGRPGRVGPTGEKGDMGDKGQKGSVG 80 G P P GD PGL G+ G G G PG PG G G GDMG G G G Sbjct: 658 GFPGPQGDRGFPGTPGRPGLPGEKGAVGQPGIGFPGPPGPKGVDGLPGDMGPPGTPGRPG 717 Query: 81 RHGKIGPIGSKGEKGDSGDIGPPGPNGEPGLP 112 +G G G +G+KG+ G +G PG G PGLP Sbjct: 718 FNGLPGNPGVQGQKGEPG-VGLPGLKGLPGLP 748 Score = 63.5 bits (153), Expect = 2e-10 Identities = 41/95 (43%), Positives = 45/95 (47%), Gaps = 10/95 (10%) Query: 23 GHPQPAGDDACSVQILVPGLKGDAGEKGDKGAPGRPGRVGPTGEKGDM------GDKGQK 76 G P G D + Q PG G G+ G G PG PG GP G G M G+KG Sbjct: 972 GTPGVPGKDGQAGQ---PGQPGPKGDPGISGTPGAPGLPGPKGSVGGMGLPGTPGEKGVP 1028 Query: 77 GSVGRHGKIGPIGSKGEKGDSGDIGPPGPNGEPGL 111 G G G G G KG KG+ G GPPG G PGL Sbjct: 1029 GIPGPQGSPGLPGDKGAKGEKGQAGPPG-IGIPGL 1062 Score = 62.4 bits (150), Expect = 4e-10 Identities = 42/112 (37%), Positives = 49/112 (43%), Gaps = 25/112 (22%) Query: 21 PSGHPQPAGDDACSVQILVPGLKGDAGEKGDKGAPGRPGRVGPTGEKGDMGDKGQKGSVG 80 P G P G + + G KGD G +G G PG PG +GP G G G KG KG+ G Sbjct: 1217 PQGQPGLPGSPGHATE----GPKGDRGPQGQPGLPGLPGPMGPPGLPGIDGVKGDKGNPG 1272 Query: 81 RHGKIGPIGSKGE---------------KGDSGDIGPP------GPNGEPGL 111 G G G KG+ G GD+GPP GP G PGL Sbjct: 1273 WPGAPGVPGPKGDPGFQGMPGIGGSPGITGSKGDMGPPGVPGFQGPKGLPGL 1324 Score = 61.6 bits (148), Expect = 7e-10 Identities = 34/76 (44%), Positives = 41/76 (53%), Gaps = 2/76 (2%) Query: 41 GLKGDAGEKGDKGAPGRPGRVGPTGEKGDMGDKGQKGSVGRHGKIGPIGSKGEKGDSGDI 100 G +G GEKG+ G PG PG V TG G+ G++G G+ G G+ GP G G G G Sbjct: 314 GRQGPQGEKGEAGPPGPPGIVIGTGPLGEKGERGYPGTPGPRGEPGPKGFPGLPGQPGPP 373 Query: 101 G--PPGPNGEPGLPCE 114 G PG G PG P E Sbjct: 374 GLPVPGQAGAPGFPGE 389 Score = 61.6 bits (148), Expect = 7e-10 Identities = 39/89 (43%), Positives = 43/89 (48%), Gaps = 14/89 (15%) Query: 40 PGLKGDAGEKGDKGAPGRPG--RVGPTGEKGDMGDKG------------QKGSVGRHGKI 85 PGL G G KG+KG PG PG GP G+KG G G Q+G+ G G Sbjct: 816 PGLSGPPGIKGEKGFPGFPGLDMPGPKGDKGAQGLPGITGQSGLPGLPGQQGAPGIPGFP 875 Query: 86 GPIGSKGEKGDSGDIGPPGPNGEPGLPCE 114 G G G G G G PGP G PGLP E Sbjct: 876 GSKGEMGVMGTPGQPGSPGPVGAPGLPGE 904 Score = 61.6 bits (148), Expect = 7e-10 Identities = 34/75 (45%), Positives = 39/75 (52%), Gaps = 2/75 (2%) Query: 40 PGLKGDAGEKGDKGAPGRPGRVGPTGEKGDMGDKGQKGSVGRHGKIGPIGSKGE--KGDS 97 PG G G+KG KG G PG G G G G++G G G G+ G GS G +G Sbjct: 1176 PGFPGAKGDKGSKGEVGFPGLAGSPGIPGSKGEQGFMGPPGPQGQPGLPGSPGHATEGPK 1235 Query: 98 GDIGPPGPNGEPGLP 112 GD GP G G PGLP Sbjct: 1236 GDRGPQGQPGLPGLP 1250 Score = 60.8 bits (146), Expect = 1e-09 Identities = 40/90 (44%), Positives = 44/90 (48%), Gaps = 16/90 (17%) Query: 39 VPGLKGDAGEKGD-------KGAPGRPGRVGPTGEKGDMG---DKGQKGSVGRHGKIGPI 88 VPG KG G G KG PG PG GP G KG G KGQ+G G G GP Sbjct: 1336 VPGAKGLPGPPGPPGPYDIIKGEPGLPGPEGPPGLKGLQGLPGPKGQQGVTGLVGIPGPP 1395 Query: 89 G------SKGEKGDSGDIGPPGPNGEPGLP 112 G + G+KG+ G GP GP G PG P Sbjct: 1396 GIPGFDGAPGQKGEMGPAGPTGPRGFPGPP 1425 Score = 60.1 bits (144), Expect = 2e-09 Identities = 43/115 (37%), Positives = 50/115 (43%), Gaps = 28/115 (24%) Query: 23 GHPQPAGDDACSVQILVPGLKGDAGEKGDKGAPGRPGRVGPTGE------KGDMGD---- 72 G P P G +PG G GE+G G PG PG G G KGD G+ Sbjct: 115 GPPGPPG---------IPGCNGTKGERGPLGPPGLPGFAGNPGPPGLPGMKGDPGEILGH 165 Query: 73 ------KGQKGSVGRHGKIGP---IGSKGEKGDSGDIGPPGPNGEPGLPCECSQL 118 KG++G G G GP G +G G G GPPGP G PG P E Q+ Sbjct: 166 VPGMLLKGERGFPGIPGTPGPPGLPGLQGPVGPPGFTGPPGPPGPPGPPGEKGQM 220 Score = 60.1 bits (144), Expect = 2e-09 Identities = 38/94 (40%), Positives = 43/94 (45%), Gaps = 11/94 (11%) Query: 23 GHPQPAGDDACSVQILVPGLKGDA-----GEKGDKGAPGRPGRVGPTGEKGDMGDKGQKG 77 G P P G +PG G A G++G +G PG PG GP G G G G KG Sbjct: 1213 GPPGPQGQPG------LPGSPGHATEGPKGDRGPQGQPGLPGLPGPMGPPGLPGIDGVKG 1266 Query: 78 SVGRHGKIGPIGSKGEKGDSGDIGPPGPNGEPGL 111 G G G G G KGD G G PG G PG+ Sbjct: 1267 DKGNPGWPGAPGVPGPKGDPGFQGMPGIGGSPGI 1300 Score = 60.1 bits (144), Expect = 2e-09 Identities = 37/89 (41%), Positives = 45/89 (50%), Gaps = 1/89 (1%) Query: 23 GHPQPAGD-DACSVQILVPGLKGDAGEKGDKGAPGRPGRVGPTGEKGDMGDKGQKGSVGR 81 G P P G D + +PG +G G KG +G PG G+ G TG G G G G G Sbjct: 1344 GPPGPPGPYDIIKGEPGLPGPEGPPGLKGLQGLPGPKGQQGVTGLVGIPGPPGIPGFDGA 1403 Query: 82 HGKIGPIGSKGEKGDSGDIGPPGPNGEPG 110 G+ G +G G G G GPPGP+G PG Sbjct: 1404 PGQKGEMGPAGPTGPRGFPGPPGPDGLPG 1432 Score = 59.3 bits (142), Expect = 3e-09 Identities = 33/78 (42%), Positives = 39/78 (50%), Gaps = 6/78 (7%) Query: 41 GLKGDAGEKGDKGA------PGRPGRVGPTGEKGDMGDKGQKGSVGRHGKIGPIGSKGEK 94 G+KG GE+G G PG G GP G G GD G+ G G G GP G+ G Sbjct: 43 GVKGQKGERGLPGLQGVIGFPGMQGPEGPQGPPGQKGDTGEPGLPGTKGTRGPPGASGYP 102 Query: 95 GDSGDIGPPGPNGEPGLP 112 G+ G G PG +G PG P Sbjct: 103 GNPGLPGIPGQDGPPGPP 120 Score = 59.3 bits (142), Expect = 3e-09 Identities = 36/86 (41%), Positives = 41/86 (47%), Gaps = 14/86 (16%) Query: 41 GLKGDAGEKGDKGAPGR---------PGRVGPTGEKGDMGDKGQKGSVG-----RHGKIG 86 G G G KGDKG+ G PG G GE+G MG G +G G H G Sbjct: 1174 GFPGFPGAKGDKGSKGEVGFPGLAGSPGIPGSKGEQGFMGPPGPQGQPGLPGSPGHATEG 1233 Query: 87 PIGSKGEKGDSGDIGPPGPNGEPGLP 112 P G +G +G G G PGP G PGLP Sbjct: 1234 PKGDRGPQGQPGLPGLPGPMGPPGLP 1259 Score = 58.9 bits (141), Expect = 4e-09 Identities = 40/93 (43%), Positives = 43/93 (46%), Gaps = 18/93 (19%) Query: 40 PGLKGDAGEKGDKGAPGRPGR--VGPTGEKGDMGDKGQKGSVG------RHGKIGPI--- 88 PG G G +GD G PG PG GP G+KG G G GS G GKI P+ Sbjct: 588 PGGVGFPGSRGDTGPPGPPGYGPAGPIGDKGQAGFPGGPGSPGLPGPKGEPGKIVPLPGP 647 Query: 89 -------GSKGEKGDSGDIGPPGPNGEPGLPCE 114 GS G G GD G PG G PGLP E Sbjct: 648 PGAEGLPGSPGFPGPQGDRGFPGTPGRPGLPGE 680 Score = 58.9 bits (141), Expect = 4e-09 Identities = 33/74 (44%), Positives = 37/74 (50%), Gaps = 2/74 (2%) Query: 39 VPGLKGDAGEKGDKGAPGRPGRVGPTGEKGDMGDKGQKGSVGRHGKIGPIGSKGEKGDSG 98 +PGLKG G G G PG G +G G G+ G G G G G+ GP G G G G Sbjct: 738 LPGLKGLPGLPGIPGTPGEKGSIGVPGVPGEHGAIGPPGLQGIRGEPGPPGLPGSVGSPG 797 Query: 99 --DIGPPGPNGEPG 110 IGPPG G PG Sbjct: 798 VPGIGPPGARGPPG 811 Score = 57.8 bits (138), Expect = 1e-08 Identities = 38/96 (39%), Positives = 45/96 (46%), Gaps = 4/96 (4%) Query: 21 PSGHPQPAGDDACSVQILVPGLKGDAGEKGDKGAPGRPGRVGPTGEKGDMGDKGQKG--S 78 P G AG ++ G G+ GE+G G PG G GP G G G G G Sbjct: 318 PQGEKGEAGPPGPPGIVIGTGPLGEKGERGYPGTPGPRGEPGPKGFPGLPGQPGPPGLPV 377 Query: 79 VGRHGKIGPIGSKGEKGDSGDIGP--PGPNGEPGLP 112 G+ G G G +GEKGD G G PGP+G GLP Sbjct: 378 PGQAGAPGFPGERGEKGDRGFPGTSLPGPSGRDGLP 413 Score = 57.8 bits (138), Expect = 1e-08 Identities = 33/73 (45%), Positives = 34/73 (46%) Query: 40 PGLKGDAGEKGDKGAPGRPGRVGPTGEKGDMGDKGQKGSVGRHGKIGPIGSKGEKGDSGD 99 PGLKG G G KG G G VG G G G G G G G GP G +G G G Sbjct: 1368 PGLKGLQGLPGPKGQQGVTGLVGIPGPPGIPGFDGAPGQKGEMGPAGPTGPRGFPGPPGP 1427 Query: 100 IGPPGPNGEPGLP 112 G PG G PG P Sbjct: 1428 DGLPGSMGPPGTP 1440 Score = 57.4 bits (137), Expect = 1e-08 Identities = 40/103 (38%), Positives = 45/103 (43%), Gaps = 16/103 (15%) Query: 21 PSGHPQPAGDDACSVQILVPGLKGDAG---EKGDKGAP---GRPGRVGPTGEKGDMGD-- 72 P G P G+ Q PG KGD G G G P G PG +G G KG+ G+ Sbjct: 478 PPGPQGPPGEIGFPGQ---PGAKGDRGLPGRDGVAGVPGPQGTPGLIGQPGAKGEPGEFY 534 Query: 73 -----KGQKGSVGRHGKIGPIGSKGEKGDSGDIGPPGPNGEPG 110 KG KG G G+ G G G G G G PGP G PG Sbjct: 535 FDLRLKGDKGDPGFPGQPGMTGRAGSPGRDGHPGLPGPKGSPG 577 Score = 57.0 bits (136), Expect = 2e-08 Identities = 36/89 (40%), Positives = 40/89 (44%), Gaps = 19/89 (21%) Query: 40 PGLKGDAGEKGDKGAPGRPGRVGPTGEKGDMGDKGQKGSVGRHGKIGPIGSKGEKGDSGD 99 PGL G G+ G G PG PG G GE+G +G G G G G P G G KGD G+ Sbjct: 105 PGLPGIPGQDGPPGPPGIPGCNGTKGERGPLGPPGLPGFAGNPG---PPGLPGMKGDPGE 161 Query: 100 I----------------GPPGPNGEPGLP 112 I G PG G PGLP Sbjct: 162 ILGHVPGMLLKGERGFPGIPGTPGPPGLP 190 Score = 57.0 bits (136), Expect = 2e-08 Identities = 35/93 (37%), Positives = 49/93 (52%), Gaps = 10/93 (10%) Query: 39 VPGLKGDAGEKGDKGAPGRPGRVGPTGE-------KGDMGDKGQKGSVGRHGKIGPIGSK 91 +PGL+G G++GD+G PG G GP G KG+ G G +G G G G G K Sbjct: 1321 LPGLQGIKGDQGDQGVPGAKGLPGPPGPPGPYDIIKGEPGLPGPEGPPGLKGLQGLPGPK 1380 Query: 92 GEKGDSGDIGPPGPNG---EPGLPCECSQLRKA 121 G++G +G +G PGP G G P + ++ A Sbjct: 1381 GQQGVTGLVGIPGPPGIPGFDGAPGQKGEMGPA 1413 Score = 56.6 bits (135), Expect = 2e-08 Identities = 38/99 (38%), Positives = 43/99 (43%), Gaps = 13/99 (13%) Query: 23 GHPQPAGDDACSVQILVPGLKGDAGEKGDKGAPGRPGRVGPTGEKGDM-------GDKGQ 75 G P GD +PG G AG G +G PG G+ G GE G+ GDKG Sbjct: 492 GQPGAKGDRG------LPGRDGVAGVPGPQGTPGLIGQPGAKGEPGEFYFDLRLKGDKGD 545 Query: 76 KGSVGRHGKIGPIGSKGEKGDSGDIGPPGPNGEPGLPCE 114 G G+ G G GS G G G GP G G GL E Sbjct: 546 PGFPGQPGMTGRAGSPGRDGHPGLPGPKGSPGSVGLKGE 584 Score = 55.5 bits (132), Expect = 5e-08 Identities = 35/91 (38%), Positives = 41/91 (45%), Gaps = 23/91 (25%) Query: 44 GDAGEKGDKGAPGRPGRVGPTGEKGDM----------------------GDKGQKGSVGR 81 GD G+ G G PG PG GP GE G + GD+G G+ GR Sbjct: 615 GDKGQAGFPGGPGSPGLPGPKGEPGKIVPLPGPPGAEGLPGSPGFPGPQGDRGFPGTPGR 674 Query: 82 HGKIGPIGSKGEKGDSGDIGPPGPNGEPGLP 112 G G G+ G+ G G GPPGP G GLP Sbjct: 675 PGLPGEKGAVGQPG-IGFPGPPGPKGVDGLP 704 Score = 55.5 bits (132), Expect = 5e-08 Identities = 36/78 (46%), Positives = 39/78 (50%), Gaps = 6/78 (7%) Query: 40 PGLKGDAGEKG-----DKGAPGRPGRVGPTGEKGDMGDKGQKGSVGRHGKIGPIGSKGEK 94 PGL G G G GA G PG GP G G G KG+KG G G P G KG+K Sbjct: 787 PGLPGSVGSPGVPGIGPPGARGPPGGQGPPGLSGPPGIKGEKGFPGFPGLDMP-GPKGDK 845 Query: 95 GDSGDIGPPGPNGEPGLP 112 G G G G +G PGLP Sbjct: 846 GAQGLPGITGQSGLPGLP 863 Score = 55.5 bits (132), Expect = 5e-08 Identities = 35/89 (39%), Positives = 40/89 (44%), Gaps = 6/89 (6%) Query: 23 GHPQPAGDDACSVQILVPGLKGDAGEKGDKGAPGRPGRVGPTGEKGDMGDKGQKGSVGRH 82 G P P G + GL+G G KG +G G G GP G G G GQKG +G Sbjct: 1360 GLPGPEGPPG------LKGLQGLPGPKGQQGVTGLVGIPGPPGIPGFDGAPGQKGEMGPA 1413 Query: 83 GKIGPIGSKGEKGDSGDIGPPGPNGEPGL 111 G GP G G G G G GP G P + Sbjct: 1414 GPTGPRGFPGPPGPDGLPGSMGPPGTPSV 1442 Score = 54.7 bits (130), Expect = 8e-08 Identities = 40/101 (39%), Positives = 46/101 (45%), Gaps = 5/101 (4%) Query: 12 ISLAFLSLLPSGHPQPAGDDACSVQILVPGLKGDAGEKGDKGAPGRPGRVGPTGEKGDMG 71 + L L LP G P G I VPG+ G+ G G G G G GP G G +G Sbjct: 736 VGLPGLKGLP-GLPGIPGTPGEKGSIGVPGVPGEHGAIGPPGLQGIRGEPGPPGLPGSVG 794 Query: 72 DKGQKGSVGRHGKIGPIGSKGEKGDSGDIGPPGPNGEPGLP 112 G G +G G GP G +G G S GPPG GE G P Sbjct: 795 SPGVPG-IGPPGARGPPGGQGPPGLS---GPPGIKGEKGFP 831 Score = 52.4 bits (124), Expect = 4e-07 Identities = 31/75 (41%), Positives = 36/75 (48%), Gaps = 3/75 (4%) Query: 41 GLKGDAGEKGDKGAPGRPGRVGPTGEKGDMGDKGQKGSVGR---HGKIGPIGSKGEKGDS 97 G +G G G KG G PG G G +G G G G+ G G+ GP G G G + Sbjct: 67 GPEGPQGPPGQKGDTGEPGLPGTKGTRGPPGASGYPGNPGLPGIPGQDGPPGPPGIPGCN 126 Query: 98 GDIGPPGPNGEPGLP 112 G G GP G PGLP Sbjct: 127 GTKGERGPLGPPGLP 141 Score = 52.0 bits (123), Expect = 5e-07 Identities = 29/78 (37%), Positives = 38/78 (48%), Gaps = 4/78 (5%) Query: 39 VPGLKGDAGEKGDKGAPGRPGRVGPTGEKGDMGDKGQKGSVGRHGKIGPIGSKGEKGDSG 98 + G +G G +G G G PG+ G G++G G G G G G G IG G KG+ G Sbjct: 472 IDGYRGPPGPQGPPGEIGFPGQPGAKGDRGLPGRDGVAGVPGPQGTPGLIGQPGAKGEPG 531 Query: 99 ----DIGPPGPNGEPGLP 112 D+ G G+PG P Sbjct: 532 EFYFDLRLKGDKGDPGFP 549 >gi|13994280 C1q and tumor necrosis factor related protein 7 isoform b [Homo sapiens] Length = 289 Score = 79.7 bits (195), Expect = 2e-15 Identities = 46/106 (43%), Positives = 55/106 (51%), Gaps = 11/106 (10%) Query: 21 PSGHPQPAGDDACSVQILVPGLKGDAGEKGDKGAPGRPGRVGPTGEKGDMGDKGQKGSVG 80 P G P G +I +PG G G KG+KG G G G TG G G+KG +G G Sbjct: 42 PPGPPGANGSPGPHGRIGLPGRDGRDGRKGEKGEKGTAGLRGKTGPLGLAGEKGDQGETG 101 Query: 81 RHGKIGPIGSKGEKGDSGDIGPPGP------NGEPGLP--CECSQL 118 + G IGP GEKG+ G IGPPGP G+PGLP C C + Sbjct: 102 KKGPIGPE---GEKGEVGPIGPPGPKGDRGEQGDPGLPGVCRCGSI 144 >gi|206597454 C1q and tumor necrosis factor related protein 7 isoform b [Homo sapiens] Length = 289 Score = 79.7 bits (195), Expect = 2e-15 Identities = 46/106 (43%), Positives = 55/106 (51%), Gaps = 11/106 (10%) Query: 21 PSGHPQPAGDDACSVQILVPGLKGDAGEKGDKGAPGRPGRVGPTGEKGDMGDKGQKGSVG 80 P G P G +I +PG G G KG+KG G G G TG G G+KG +G G Sbjct: 42 PPGPPGANGSPGPHGRIGLPGRDGRDGRKGEKGEKGTAGLRGKTGPLGLAGEKGDQGETG 101 Query: 81 RHGKIGPIGSKGEKGDSGDIGPPGP------NGEPGLP--CECSQL 118 + G IGP GEKG+ G IGPPGP G+PGLP C C + Sbjct: 102 KKGPIGPE---GEKGEVGPIGPPGPKGDRGEQGDPGLPGVCRCGSI 144 >gi|206597452 C1q and tumor necrosis factor related protein 7 isoform a [Homo sapiens] Length = 296 Score = 79.7 bits (195), Expect = 2e-15 Identities = 46/106 (43%), Positives = 55/106 (51%), Gaps = 11/106 (10%) Query: 21 PSGHPQPAGDDACSVQILVPGLKGDAGEKGDKGAPGRPGRVGPTGEKGDMGDKGQKGSVG 80 P G P G +I +PG G G KG+KG G G G TG G G+KG +G G Sbjct: 49 PPGPPGANGSPGPHGRIGLPGRDGRDGRKGEKGEKGTAGLRGKTGPLGLAGEKGDQGETG 108 Query: 81 RHGKIGPIGSKGEKGDSGDIGPPGP------NGEPGLP--CECSQL 118 + G IGP GEKG+ G IGPPGP G+PGLP C C + Sbjct: 109 KKGPIGPE---GEKGEVGPIGPPGPKGDRGEQGDPGLPGVCRCGSI 151 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.314 0.136 0.409 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 12,482,629 Number of Sequences: 37866 Number of extensions: 679430 Number of successful extensions: 26190 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 210 Number of HSP's successfully gapped in prelim test: 155 Number of HSP's that attempted gapping in prelim test: 2065 Number of HSP's gapped (non-prelim): 6424 length of query: 271 length of database: 18,247,518 effective HSP length: 101 effective length of query: 170 effective length of database: 14,423,052 effective search space: 2451918840 effective search space used: 2451918840 T: 11 A: 40 X1: 16 ( 7.2 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 42 (21.9 bits) S2: 61 (28.1 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.