Search of human proteins with 109148552

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|109148552 keratin 3 [Homo sapiens]
         (628 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|109148552 keratin 3 [Homo sapiens]                                1244   0.0  
gi|153791670 keratin 76 [Homo sapiens]                                907   0.0  
gi|119395754 keratin 5 [Homo sapiens]                                 714   0.0  
gi|47132620 keratin 2 [Homo sapiens]                                  704   0.0  
gi|119395750 keratin 1 [Homo sapiens]                                 697   0.0  
gi|5031839 keratin 6A [Homo sapiens]                                  679   0.0  
gi|119703753 keratin 6B [Homo sapiens]                                678   0.0  
gi|155969697 keratin 6C [Homo sapiens]                                675   0.0  
gi|109255249 keratin 4 [Homo sapiens]                                 640   0.0  
gi|153791158 keratin 75 [Homo sapiens]                                613   e-175
gi|194018511 keratin 77 [Homo sapiens]                                609   e-174
gi|32567786 keratin 6L [Homo sapiens]                                 580   e-165
gi|28173564 keratin 73 [Homo sapiens]                                 558   e-159
gi|15618995 keratin 71 [Homo sapiens]                                 551   e-157
gi|148612803 keratin 6 irs4 [Homo sapiens]                            550   e-156
gi|28372503 keratin 72 isoform 1 [Homo sapiens]                       528   e-150
gi|226246663 keratin 72 isoform 1 [Homo sapiens]                      528   e-150
gi|4504919 keratin 8 [Homo sapiens]                                   503   e-142
gi|67782365 keratin 7 [Homo sapiens]                                  488   e-138
gi|15431316 keratin, hair, basic, 4 [Homo sapiens]                    468   e-132
gi|89357932 keratin 5b [Homo sapiens]                                 460   e-129
gi|4504935 keratin 85 [Homo sapiens]                                  418   e-117
gi|226246665 keratin 72 isoform 2 [Homo sapiens]                      415   e-116
gi|27477127 keratin 82 [Homo sapiens]                                 410   e-114
gi|169790853 keratin, hair, basic, 1 [Homo sapiens]                   410   e-114
gi|239755818 PREDICTED: hypothetical protein isoform 2 [Homo sap...   408   e-114
gi|239755816 PREDICTED: hypothetical protein isoform 1 [Homo sap...   408   e-114
gi|239755814 PREDICTED: hypothetical protein isoform 3 [Homo sap...   408   e-114
gi|14318422 keratin 86 [Homo sapiens]                                 408   e-114
gi|169790841 keratin 83 [Homo sapiens]                                405   e-113

>gi|109148552 keratin 3 [Homo sapiens]
          Length = 628

 Score = 1244 bits (3220), Expect = 0.0
 Identities = 628/628 (100%), Positives = 628/628 (100%)

Query: 1   MSRQASKTSGGGSQGFSGRSAVVSGSSRMSCVAHSGGAGGGAYGFRSGAGGFGSRSLYNL 60
           MSRQASKTSGGGSQGFSGRSAVVSGSSRMSCVAHSGGAGGGAYGFRSGAGGFGSRSLYNL
Sbjct: 1   MSRQASKTSGGGSQGFSGRSAVVSGSSRMSCVAHSGGAGGGAYGFRSGAGGFGSRSLYNL 60

Query: 61  GGNKSISISVAAGGSRAGGFGGGRSSCAFAGGYGGGFGSGYGGGFGGGFGGGRGMGGGFG 120
           GGNKSISISVAAGGSRAGGFGGGRSSCAFAGGYGGGFGSGYGGGFGGGFGGGRGMGGGFG
Sbjct: 61  GGNKSISISVAAGGSRAGGFGGGRSSCAFAGGYGGGFGSGYGGGFGGGFGGGRGMGGGFG 120

Query: 121 GAGGFGGAGGFGGAGGFGGPGGFGGSGGFGGPGSLGSPGGFGPGGFPGGIQEVTINQSLL 180
           GAGGFGGAGGFGGAGGFGGPGGFGGSGGFGGPGSLGSPGGFGPGGFPGGIQEVTINQSLL
Sbjct: 121 GAGGFGGAGGFGGAGGFGGPGGFGGSGGFGGPGSLGSPGGFGPGGFPGGIQEVTINQSLL 180

Query: 181 QPLNVEIDPQIGQVKAQEREQIKTLNNKFASFIDKVRFLEQQNKVLETKWNLLQQQGTSS 240
           QPLNVEIDPQIGQVKAQEREQIKTLNNKFASFIDKVRFLEQQNKVLETKWNLLQQQGTSS
Sbjct: 181 QPLNVEIDPQIGQVKAQEREQIKTLNNKFASFIDKVRFLEQQNKVLETKWNLLQQQGTSS 240

Query: 241 ISGTNNLEPLFENHINYLRSYLDNILGERGRLDSELKNMEDLVEDFKKKYEDEINKRTAA 300
           ISGTNNLEPLFENHINYLRSYLDNILGERGRLDSELKNMEDLVEDFKKKYEDEINKRTAA
Sbjct: 241 ISGTNNLEPLFENHINYLRSYLDNILGERGRLDSELKNMEDLVEDFKKKYEDEINKRTAA 300

Query: 301 ENEFVTLKKDVDSAYMNKVELQAKVDALIDEIDFLRTLYDAELSQMQSHISDTSVVLSMD 360
           ENEFVTLKKDVDSAYMNKVELQAKVDALIDEIDFLRTLYDAELSQMQSHISDTSVVLSMD
Sbjct: 301 ENEFVTLKKDVDSAYMNKVELQAKVDALIDEIDFLRTLYDAELSQMQSHISDTSVVLSMD 360

Query: 361 NNRSLDLDSIIAEVRAQYEDIAQRSKAEAEALYQTKLGELQTTAGRHGDDLRNTKSEIIE 420
           NNRSLDLDSIIAEVRAQYEDIAQRSKAEAEALYQTKLGELQTTAGRHGDDLRNTKSEIIE
Sbjct: 361 NNRSLDLDSIIAEVRAQYEDIAQRSKAEAEALYQTKLGELQTTAGRHGDDLRNTKSEIIE 420

Query: 421 LNRMIQRLRAEIEGVKKQNANLQTAIAEAEQHGEMALKDANAKLQELQAALQQAKDDLAR 480
           LNRMIQRLRAEIEGVKKQNANLQTAIAEAEQHGEMALKDANAKLQELQAALQQAKDDLAR
Sbjct: 421 LNRMIQRLRAEIEGVKKQNANLQTAIAEAEQHGEMALKDANAKLQELQAALQQAKDDLAR 480

Query: 481 LLRDYQELMNVKLALDVEIATYRKLLEGEEYRMSGECPSAVSISVVSSSTTSASAGGYGG 540
           LLRDYQELMNVKLALDVEIATYRKLLEGEEYRMSGECPSAVSISVVSSSTTSASAGGYGG
Sbjct: 481 LLRDYQELMNVKLALDVEIATYRKLLEGEEYRMSGECPSAVSISVVSSSTTSASAGGYGG 540

Query: 541 GYGGGMGGGLGGGFSAGGGSGSGFGRGGGGGIGGGFGGGSSGFSGGSGFGSISGARYGVS 600
           GYGGGMGGGLGGGFSAGGGSGSGFGRGGGGGIGGGFGGGSSGFSGGSGFGSISGARYGVS
Sbjct: 541 GYGGGMGGGLGGGFSAGGGSGSGFGRGGGGGIGGGFGGGSSGFSGGSGFGSISGARYGVS 600

Query: 601 GGGFSSASNRGGSIKFSQSSQSSQRYSR 628
           GGGFSSASNRGGSIKFSQSSQSSQRYSR
Sbjct: 601 GGGFSSASNRGGSIKFSQSSQSSQRYSR 628


>gi|153791670 keratin 76 [Homo sapiens]
          Length = 638

 Score =  907 bits (2345), Expect = 0.0
 Identities = 486/654 (74%), Positives = 525/654 (80%), Gaps = 45/654 (6%)

Query: 1   MSRQASKTS-GGGSQGFSGRSAVVSGSSRMSCVAHSGGAGGGAYGFRSGAGGFGSRSLYN 59
           M+RQ  K S  G SQGFSGRSAVVSGSSRMSCVA SGGAGGGA GFRSGAG FGSRSLYN
Sbjct: 1   MNRQVCKKSFSGRSQGFSGRSAVVSGSSRMSCVARSGGAGGGACGFRSGAGSFGSRSLYN 60

Query: 60  LGGNKSISISVAAGGSRAGGFGGGRSSCAFAGGYGGGFGSGYGGGFGGGFGGGRGMGGGF 119
           LG NKSISISVAAG SRAGGFGGGRSSC FAGGYGGGFG    G +GGGFGGGRG+G GF
Sbjct: 61  LGSNKSISISVAAGSSRAGGFGGGRSSCGFAGGYGGGFG----GSYGGGFGGGRGVGSGF 116

Query: 120 GGAGGFGGAGGFGGAGGFGGPGGFGGSGGFGGPGSLGSPGGFGPGGFPGGIQEVTINQSL 179
           GGAGG      FGGAGGFGGPG FGG G FGGPG      GFGPGGFPGGIQEV +NQSL
Sbjct: 117 GGAGG------FGGAGGFGGPGVFGGPGSFGGPG------GFGPGGFPGGIQEVIVNQSL 164

Query: 180 LQPLNVEIDPQIGQVKAQEREQIKTLNNKFASFIDKVRFLEQQNKVLETKWNLLQQQGTS 239
           LQPLNVEIDPQIGQVKAQEREQIKTLNNKFASFIDKVRFLEQQNKVLETKW LLQQQ T 
Sbjct: 165 LQPLNVEIDPQIGQVKAQEREQIKTLNNKFASFIDKVRFLEQQNKVLETKWELLQQQTTG 224

Query: 240 SISGTNNLEPLFENHINYLRSYLDNILGERGRLDSELKNMEDLVEDFKKKYEDEINKRTA 299
           S  G ++LEP FE++I++L   LD++LGERG L+ ELK+M+DLVEDFKKKYEDEINKRTA
Sbjct: 225 S--GPSSLEPCFESYISFLCKQLDSLLGERGNLEGELKSMQDLVEDFKKKYEDEINKRTA 282

Query: 300 AENEFVTLKKDVDSAYMNKVELQAKVDALIDEIDFLRTLYDAELSQMQSHISDTSVVLSM 359
           AENEFV LKKDVD+A+MNKVELQAKVD+L DE+ FLRTLY+ ELSQMQSH SDTSVVLSM
Sbjct: 283 AENEFVGLKKDVDAAFMNKVELQAKVDSLTDEVSFLRTLYEMELSQMQSHASDTSVVLSM 342

Query: 360 DNNRSLDLDSIIAEVRAQYEDIAQRSKAEAEALYQTKLGELQTTAGRHGDDLRNTKSEII 419
           DNNR LDL SIIAEVRAQYE+IAQRSK+EAEALYQTKLGELQTTAGRHGDDLRNTKSEI+
Sbjct: 343 DNNRCLDLGSIIAEVRAQYEEIAQRSKSEAEALYQTKLGELQTTAGRHGDDLRNTKSEIM 402

Query: 420 ELNRMIQRLRAEIEGVKKQNANLQTAIAEAEQHGEMALKDANAKLQELQAALQQAKDDLA 479
           ELNRMIQRLRAEIE VKKQNANLQTAIAEAEQ GEMALKDANAKLQ+LQ ALQ+AKDDLA
Sbjct: 403 ELNRMIQRLRAEIENVKKQNANLQTAIAEAEQRGEMALKDANAKLQDLQTALQKAKDDLA 462

Query: 480 RLLRDYQELMNVKLALDVEIATYRKLLEGEEYRMSGECPSAVSISVVSSSTTSASAGGYG 539
           RLLRDYQELMNVKLALDVEIATYRKLLEGEE RMSGEC SAV ISVVS+ T+++ + G  
Sbjct: 463 RLLRDYQELMNVKLALDVEIATYRKLLEGEECRMSGECQSAVCISVVSNVTSTSGSSGSS 522

Query: 540 GGYGGGMGGGLGGGFSAGGGSGSGFGRGGGGGIGGGFGGGSSGFSGG------------- 586
            G  GG+ G   GG+  G  S S  G G  GG G G+GG SSG +GG             
Sbjct: 523 RGVFGGVSGSGSGGYKGGSSSSSSSGYGVSGGSGSGYGGVSSGSTGGRGSSGSYQSSSSG 582

Query: 587 -------------SGFGSISGARYGVSGGGFSSASNRGGSIKFSQSSQSSQRYS 627
                        SG GS SG+     G G+ S      SI+FSQ++ SSQ  S
Sbjct: 583 SRLGGAGSISVSHSGMGSSSGSIQTSGGSGYKSGGGGSTSIRFSQTTSSSQHSS 636


>gi|119395754 keratin 5 [Homo sapiens]
          Length = 590

 Score =  714 bits (1842), Expect = 0.0
 Identities = 406/637 (63%), Positives = 466/637 (73%), Gaps = 63/637 (9%)

Query: 1   MSRQASKT-SGGGSQGFSGRSAVVSGSSRMS--CVAHSGGAGGGAYGFRS-----GAGGF 52
           MSRQ+S +   GGS+ FS  SA+    SR S   V+ SGG GGG +G  S     G GG+
Sbjct: 1   MSRQSSVSFRSGGSRSFSTASAITPSVSRTSFTSVSRSGGGGGGGFGRVSLAGACGVGGY 60

Query: 53  GSRSLYNLGGNKSISISVAAGGSRAGGFGGGRSSCAFAGGYGGGFGSGYGGGFGG-GFGG 111
           GSRSLYNLGG+K ISIS + G  R            F  G GGG+G G G G  G GFGG
Sbjct: 61  GSRSLYNLGGSKRISISTSGGSFRN----------RFGAGAGGGYGFGGGAG-SGFGFGG 109

Query: 112 GRGMGGGFGGAGGFGGAGGFGGAGGFGGPGGFGGSGGFGGPGSLGSPGGFGPGGFPGGIQ 171
           G G G G GG  GFG                    GGFGGPG    P        PGGIQ
Sbjct: 110 GAGGGFGLGGGAGFG--------------------GGFGGPGFPVCP--------PGGIQ 141

Query: 172 EVTINQSLLQPLNVEIDPQIGQVKAQEREQIKTLNNKFASFIDKVRFLEQQNKVLETKWN 231
           EVT+NQSLL PLN++IDP I +V+ +EREQIKTLNNKFASFIDKVRFLEQQNKVL+TKW 
Sbjct: 142 EVTVNQSLLTPLNLQIDPSIQRVRTEEREQIKTLNNKFASFIDKVRFLEQQNKVLDTKWT 201

Query: 232 LLQQQGTSSISGTNNLEPLFENHINYLRSYLDNILGERGRLDSELKNMEDLVEDFKKKYE 291
           LLQ+QGT ++    NLEPLFE +IN LR  LD+I+GERGRLDSEL+NM+DLVEDFK KYE
Sbjct: 202 LLQEQGTKTV--RQNLEPLFEQYINNLRRQLDSIVGERGRLDSELRNMQDLVEDFKNKYE 259

Query: 292 DEINKRTAAENEFVTLKKDVDSAYMNKVELQAKVDALIDEIDFLRTLYDAELSQMQSHIS 351
           DEINKRT AENEFV LKKDVD+AYMNKVEL+AKVDAL+DEI+F++  +DAELSQMQ+H+S
Sbjct: 260 DEINKRTTAENEFVMLKKDVDAAYMNKVELEAKVDALMDEINFMKMFFDAELSQMQTHVS 319

Query: 352 DTSVVLSMDNNRSLDLDSIIAEVRAQYEDIAQRSKAEAEALYQTKLGELQTTAGRHGDDL 411
           DTSVVLSMDNNR+LDLDSIIAEV+AQYE+IA RS+ EAE+ YQTK  ELQ TAGRHGDDL
Sbjct: 320 DTSVVLSMDNNRNLDLDSIIAEVKAQYEEIANRSRTEAESWYQTKYEELQQTAGRHGDDL 379

Query: 412 RNTKSEIIELNRMIQRLRAEIEGVKKQNANLQTAIAEAEQHGEMALKDANAKLQELQAAL 471
           RNTK EI E+NRMIQRLRAEI+ VKKQ ANLQ AIA+AEQ GE+ALKDA  KL EL+ AL
Sbjct: 380 RNTKHEISEMNRMIQRLRAEIDNVKKQCANLQNAIADAEQRGELALKDARNKLAELEEAL 439

Query: 472 QQAKDDLARLLRDYQELMNVKLALDVEIATYRKLLEGEEYRMSGECPSAVSISVVSSSTT 531
           Q+AK D+ARLLR+YQELMN KLALDVEIATYRKLLEGEE R+SGE    V+ISVV+SS +
Sbjct: 440 QKAKQDMARLLREYQELMNTKLALDVEIATYRKLLEGEECRLSGEGVGPVNISVVTSSVS 499

Query: 532 S--ASAGGYGGGYGGGMGGGLGGGFSAGGGSGSGFGRGGGG-GIGGGFGGGSSGFSGGSG 588
           S   S  GYGGG GGG+GGGLGGG  AGG SGS +    GG G+GGG   G SGFS  SG
Sbjct: 500 SGYGSGSGYGGGLGGGLGGGLGGGL-AGGSSGSYYSSSSGGVGLGGGLSVGGSGFSASSG 558

Query: 589 FGSISGARYGVSGGGFSSASNRGGSIKFSQSSQSSQR 625
            G   G  +G SGGG SS      S+KF  ++ SS++
Sbjct: 559 RG--LGVGFG-SGGGSSS------SVKFVSTTSSSRK 586


>gi|47132620 keratin 2 [Homo sapiens]
          Length = 639

 Score =  704 bits (1816), Expect = 0.0
 Identities = 402/626 (64%), Positives = 457/626 (73%), Gaps = 57/626 (9%)

Query: 10  GGGSQGFSGRSAVVSGSSR-----MSCVAHSGGAGGGAYGFRSGAGGFGSRSLYNLGGNK 64
           GGG +GFS  SAVVSG SR      SC++  GG GGG      G GGFGSRSL  LGG K
Sbjct: 16  GGGFRGFSSGSAVVSGGSRRSTSSFSCLSRHGGGGGGF-----GGGGFGSRSLVGLGGTK 70

Query: 65  SISISVAAGGSRAGGFGGGRSSCAFAGGYGGGFGSGYGGGFGGGFGGGRGMGGGFGGAGG 124
           SISISVA GG   GGFG        AGG+GG          GGGFGGG   GGG G +GG
Sbjct: 71  SISISVAGGG---GGFGA-------AGGFGGR---------GGGFGGGSSFGGGSGFSGG 111

Query: 125 FGGAGGFGGAGGFGGPGGFGGSGGFGGPGSLGSPGGFGPGGFPGGIQEVTINQSLLQPLN 184
                GFGG GGFGG G FGG GG GG G LG PGGFGPGG+PGGI EV++NQSLLQPLN
Sbjct: 112 -----GFGG-GGFGG-GRFGGFGGPGGVGGLGGPGGFGPGGYPGGIHEVSVNQSLLQPLN 164

Query: 185 VEIDPQIGQVKAQEREQIKTLNNKFASFIDKVRFLEQQNKVLETKWNLLQQQ--GTSSIS 242
           V++DP+I  VKAQEREQIKTLNNKFASFIDKVRFLEQQN+VL+TKW LLQQ   GT  I 
Sbjct: 165 VKVDPEIQNVKAQEREQIKTLNNKFASFIDKVRFLEQQNQVLQTKWELLQQMNVGTRPI- 223

Query: 243 GTNNLEPLFENHINYLRSYLDNILGERGRLDSELKNMEDLVEDFKKKYEDEINKRTAAEN 302
              NLEP+F+ +I+ L+ YLD +  ER   +SEL NM+DLVED+KKKYEDEINKRTAAEN
Sbjct: 224 ---NLEPIFQGYIDSLKRYLDGLTAERTSQNSELNNMQDLVEDYKKKYEDEINKRTAAEN 280

Query: 303 EFVTLKKDVDSAYMNKVELQAKVDALIDEIDFLRTLYDAELSQMQSHISDTSVVLSMDNN 362
           +FVTLKKDVD+AYM KVELQ+KVD L  EI+FL+ LYDAE+SQ+   ++DT+V+LSMDN+
Sbjct: 281 DFVTLKKDVDNAYMIKVELQSKVDLLNQEIEFLKVLYDAEISQIHQSVTDTNVILSMDNS 340

Query: 363 RSLDLDSIIAEVRAQYEDIAQRSKAEAEALYQTKLGELQTTAGRHGDDLRNTKSEIIELN 422
           R+LDLDSIIAEV+AQYE+IAQRSK EAEALY +K  ELQ T GRHGD L+  K EI ELN
Sbjct: 341 RNLDLDSIIAEVKAQYEEIAQRSKEEAEALYHSKYEELQVTVGRHGDSLKEIKIEISELN 400

Query: 423 RMIQRLRAEIEGVKKQNANLQTAIAEAEQHGEMALKDANAKLQELQAALQQAKDDLARLL 482
           R+IQRL+ EI  VKKQ  N+Q AIA+AEQ GE ALKDA  KL +L+ ALQQAK+DLARLL
Sbjct: 401 RVIQRLQGEIAHVKKQCKNVQDAIADAEQRGEHALKDARNKLNDLEEALQQAKEDLARLL 460

Query: 483 RDYQELMNVKLALDVEIATYRKLLEGEEYRMSGECPSAVSISVVSSSTTSASAGGYGGGY 542
           RDYQELMNVKLALDVEIATYRKLLEGEE RMSG+  S V++SV SS+ +S  A     G 
Sbjct: 461 RDYQELMNVKLALDVEIATYRKLLEGEECRMSGDLSSNVTVSVTSSTISSNVASKAAFGG 520

Query: 543 GGGMGGGLGGGFSAG------GG--SGSGFGRGGGGGI-GGGFG-----GGSSGFSGGSG 588
            GG G   GGG+S+G      GG  SGS  G GGGG I GGG+G     GG  G  GGS 
Sbjct: 521 SGGRGSSSGGGYSSGSSSYGSGGRQSGSRGGSGGGGSISGGGYGSGGGSGGRYGSGGGSK 580

Query: 589 FGSISGARYGVSGGGFSS-ASNRGGS 613
            GSISG  YG  GG  SS   +RGGS
Sbjct: 581 GGSISGGGYGSGGGKHSSGGGSRGGS 606



 Score = 83.2 bits (204), Expect = 7e-16
 Identities = 59/134 (44%), Positives = 66/134 (49%), Gaps = 15/134 (11%)

Query: 26  SSRMSCVAHSGGAGGGAYGFRSGAGGFGSRSLYNLGGNKSISISVAAGGSRAGGFGGGRS 85
           SS ++  A  GG+GG   G  SG G     S Y  GG +S        GSR G  GGG  
Sbjct: 509 SSNVASKAAFGGSGGR--GSSSGGGYSSGSSSYGSGGRQS--------GSRGGSGGGGSI 558

Query: 86  SCAFAGGYGGGFGSGYGGGFGGGFGGGRGMGGGFGGAGGFGGAGGFGGAGGFGGPGGFGG 145
           S    GGYG G GSG   G GGG  GG   GGG+G  GG   +GG G  GG    GG+ G
Sbjct: 559 S---GGGYGSGGGSGGRYGSGGGSKGGSISGGGYGSGGGKHSSGG-GSRGGSSSGGGY-G 613

Query: 146 SGGFGGPGSLGSPG 159
           SGG G     GS G
Sbjct: 614 SGGGGSSSVKGSSG 627



 Score = 70.1 bits (170), Expect = 6e-12
 Identities = 45/118 (38%), Positives = 53/118 (44%), Gaps = 7/118 (5%)

Query: 60  LGGNKSISISVAAGGSRAGGFGGGRSSCAFAGGYGGGFGSGYGGGFGGGFGGGRGMGGGF 119
           +  N +   +    G R    GGG SS + + G GG      GG  GGG   G G G G 
Sbjct: 508 ISSNVASKAAFGGSGGRGSSSGGGYSSGSSSYGSGGRQSGSRGGSGGGGSISGGGYGSGG 567

Query: 120 GGAGGFGGAGGFGG----AGGFGGPGGFGGSGGFGGPGSLGSPGGFGPGGFPGGIQEV 173
           G  G +G  GG  G     GG+G  GG   SGG G  G   S GG+G GG  GG   V
Sbjct: 568 GSGGRYGSGGGSKGGSISGGGYGSGGGKHSSGG-GSRGGSSSGGGYGSGG--GGSSSV 622



 Score = 61.6 bits (148), Expect = 2e-09
 Identities = 52/136 (38%), Positives = 62/136 (45%), Gaps = 27/136 (19%)

Query: 2   SRQASKTSGGGSQG---------FSGRSAVVSGSSRMSCVAHSGGAG---GGAYGFRSGA 49
           S  ASK + GGS G          SG S+  SG  +      SGG G   GG YG   G+
Sbjct: 510 SNVASKAAFGGSGGRGSSSGGGYSSGSSSYGSGGRQSGSRGGSGGGGSISGGGYGSGGGS 569

Query: 50  GG-FGSRSLYNLGGNKSISISVAAGGSRAGGFGGGRSSCAFAGGYGGGFGSGYGGGFGGG 108
           GG +GS      GG+K  SIS        GG+G G    +  GG  G  GS  GGG+G G
Sbjct: 570 GGRYGSG-----GGSKGGSIS-------GGGYGSGGGKHSSGGGSRG--GSSSGGGYGSG 615

Query: 109 FGGGRGMGGGFGGAGG 124
            GG   + G  G A G
Sbjct: 616 GGGSSSVKGSSGEAFG 631


>gi|119395750 keratin 1 [Homo sapiens]
          Length = 644

 Score =  697 bits (1799), Expect = 0.0
 Identities = 404/634 (63%), Positives = 456/634 (71%), Gaps = 51/634 (8%)

Query: 1   MSRQASKTSGGGSQG-FSGRSAVVSGSSRM---SCVAHSGGAGG------GAYGFRSGAG 50
           MSRQ S  SG  S G FS  SA +    R    S    SGG GG      G  G     G
Sbjct: 1   MSRQFSSRSGYRSGGGFSSGSAGIINYQRRTTSSSTRRSGGGGGRFSSCGGGGGSFGAGG 60

Query: 51  GFGSRSLYNLGGNKSISISVAAGGSRAGGFGGGRSSCAFAGGYGGGFGSGYGGGFGGGFG 110
           GFGSRSL NLGG+KSISISVA GG R  GFGG         GYGG       GGFGGG  
Sbjct: 61  GFGSRSLVNLGGSKSISISVARGGGRGSGFGG---------GYGG-------GGFGGGGF 104

Query: 111 GGRGMGGGFGGAGGFGGAGGFGGAGGFGGPGGFGGSGGFGGPGSLGSPGGFGPGGFPGGI 170
           GG G GGG  G GGFGG G   G GGFGG GGFGG GG+GG        G+GP   PGGI
Sbjct: 105 GGGGFGGGGIGGGGFGGFGS--GGGGFGG-GGFGG-GGYGG--------GYGPVCPPGGI 152

Query: 171 QEVTINQSLLQPLNVEIDPQIGQVKAQEREQIKTLNNKFASFIDKVRFLEQQNKVLETKW 230
           QEVTINQSLLQPLNVEIDP+I +VK++EREQIK+LNN+FASFIDKVRFLEQQN+VL+TKW
Sbjct: 153 QEVTINQSLLQPLNVEIDPEIQKVKSREREQIKSLNNQFASFIDKVRFLEQQNQVLQTKW 212

Query: 231 NLLQQQGTSSISGTNNLEPLFENHINYLRSYLDNILGERGRLDSELKNMEDLVEDFKKKY 290
            LLQQ  TS+   T+NLEP FE+ IN LR  +D +  ++ RLDSELKNM+D+VED++ KY
Sbjct: 213 ELLQQVDTST--RTHNLEPYFESFINNLRRRVDQLKSDQSRLDSELKNMQDMVEDYRNKY 270

Query: 291 EDEINKRTAAENEFVTLKKDVDSAYMNKVELQAKVDALIDEIDFLRTLYDAELSQMQSHI 350
           EDEINKRT AENEFVT+KKDVD AYM KV+LQAK+D L  EIDFL  LY AELSQMQ+ I
Sbjct: 271 EDEINKRTNAENEFVTIKKDVDGAYMTKVDLQAKLDNLQQEIDFLTALYQAELSQMQTQI 330

Query: 351 SDTSVVLSMDNNRSLDLDSIIAEVRAQYEDIAQRSKAEAEALYQTKLGELQTTAGRHGDD 410
           S+T+V+LSMDNNRSLDLDSIIAEV+AQYEDIAQ+SKAEAE+LYQ+K  ELQ TAGRHGD 
Sbjct: 331 SETNVILSMDNNRSLDLDSIIAEVKAQYEDIAQKSKAEAESLYQSKYEELQITAGRHGDS 390

Query: 411 LRNTKSEIIELNRMIQRLRAEIEGVKKQNANLQTAIAEAEQHGEMALKDANAKLQELQAA 470
           +RN+K EI ELNR+IQRLR+EI+ VKKQ +NLQ +I++AEQ GE ALKDA  KL +L+ A
Sbjct: 391 VRNSKIEISELNRVIQRLRSEIDNVKKQISNLQQSISDAEQRGENALKDAKNKLNDLEDA 450

Query: 471 LQQAKDDLARLLRDYQELMNVKLALDVEIATYRKLLEGEEYRMSGECPSAVSISVVSSST 530
           LQQAK+DLARLLRDYQELMN KLALD+EIATYR LLEGEE RMSGEC   VS+SV +S T
Sbjct: 451 LQQAKEDLARLLRDYQELMNTKLALDLEIATYRTLLEGEESRMSGECAPNVSVSVSTSHT 510

Query: 531 T---SASAGGYGGGYG-GGMGGGLGGG-FSAGGGSGSGFGRGGGGGIGGGFGGGSSGFSG 585
           T     S GG GGGYG GG   G GGG + +GGG G G G  G GG   G GGGS G  G
Sbjct: 511 TISGGGSRGGGGGGYGSGGSSYGSGGGSYGSGGGGGGGRGSYGSGGSSYGSGGGSYGSGG 570

Query: 586 GS------GFGSISGARYGVSGGGFSSASNRGGS 613
           G       G GS SG   G SGGG   +S   GS
Sbjct: 571 GGGGHGSYGSGSSSGGYRGGSGGGGGGSSGGRGS 604



 Score = 82.0 bits (201), Expect = 1e-15
 Identities = 56/158 (35%), Positives = 70/158 (44%), Gaps = 22/158 (13%)

Query: 23  VSGSSRMSCVAHSGGAGGGAYGFRSGAGGFGSRSLYNLGGNKSISISVAAGGSRAGGFGG 82
           VS S+  + ++  G  GGG  G+ SG   +GS                  GGS   G GG
Sbjct: 503 VSVSTSHTTISGGGSRGGGGGGYGSGGSSYGS-----------------GGGSYGSGGGG 545

Query: 83  GRSSCAFAGGYGGGFGSGYGGGFGGGFGGGRGMGGGFGGAGGFGGAGGFGGAGGFGGPGG 142
           G    ++  G G  +GSG G    GG GGG G  G    +GG+ G  G GG G  GG G 
Sbjct: 546 GGGRGSYGSG-GSSYGSGGGSYGSGGGGGGHGSYGSGSSSGGYRGGSGGGGGGSSGGRGS 604

Query: 143 FGGS--GGFGGPGSLGSPGGFGPGGFPGGIQEVTINQS 178
            GGS  G  GG GS  S GG    G    ++ V+   S
Sbjct: 605 GGGSSGGSIGGRGS--SSGGVKSSGGSSSVKFVSTTYS 640



 Score = 81.3 bits (199), Expect = 3e-15
 Identities = 54/130 (41%), Positives = 64/130 (49%), Gaps = 6/130 (4%)

Query: 45  FRSGAGGFGSRSLYNLGGNKSISISVA----AGGSRAGGFGGGRSSCAFAGGYGGG-FGS 99
           +R+   G  SR       N S+S+S +    +GG   GG GGG  S   + G GGG +GS
Sbjct: 482 YRTLLEGEESRMSGECAPNVSVSVSTSHTTISGGGSRGGGGGGYGSGGSSYGSGGGSYGS 541

Query: 100 GYGGGFGGGFGGGRGMGGGFGGAGGFGGAGGFGGAGGFGGPGGFGGSGGFGGPGSLGSPG 159
           G GGG G G  G  G   G GG G +G  GG GG G +G     GG  G  G G  GS G
Sbjct: 542 GGGGGGGRGSYGSGGSSYGSGG-GSYGSGGGGGGHGSYGSGSSSGGYRGGSGGGGGGSSG 600

Query: 160 GFGPGGFPGG 169
           G G GG   G
Sbjct: 601 GRGSGGGSSG 610



 Score = 81.3 bits (199), Expect = 3e-15
 Identities = 59/148 (39%), Positives = 68/148 (45%), Gaps = 24/148 (16%)

Query: 1   MSRQASKTSGGGSQGFSGRSAVVSGSSRMSCVAHSGGAGGGAYGFRSGAGGFGSRSLYNL 60
           +S   +  SGGGS+G  G      GSS         G+GGG+YG  SG GG G R  Y  
Sbjct: 505 VSTSHTTISGGGSRGGGGGGYGSGGSSY--------GSGGGSYG--SGGGGGGGRGSYGS 554

Query: 61  GGNKSISISVAAGGSRAGGFGGGRSSCAFAGGYGGGFGSGYGGGFGGGFGGGRGMGGGFG 120
           GG+     S  +GG   G  GGG       G YG G  SG   G+ GG GGG G   G  
Sbjct: 555 GGS-----SYGSGGGSYGSGGGGGGH----GSYGSGSSSG---GYRGGSGGGGGGSSGGR 602

Query: 121 GAGGFGGAGGFGGAGGFGGPGGFGGSGG 148
           G+GG    G  GG G     GG   SGG
Sbjct: 603 GSGGGSSGGSIGGRG--SSSGGVKSSGG 628



 Score = 36.6 bits (83), Expect = 0.072
 Identities = 21/46 (45%), Positives = 23/46 (50%), Gaps = 2/46 (4%)

Query: 527 SSSTTSASAGGYGGGYGG--GMGGGLGGGFSAGGGSGSGFGRGGGG 570
           SS      +GG GGG  G  G GGG  GG   G GS SG  +  GG
Sbjct: 583 SSGGYRGGSGGGGGGSSGGRGSGGGSSGGSIGGRGSSSGGVKSSGG 628


>gi|5031839 keratin 6A [Homo sapiens]
          Length = 564

 Score =  679 bits (1752), Expect = 0.0
 Identities = 385/585 (65%), Positives = 428/585 (73%), Gaps = 51/585 (8%)

Query: 7   KTSGGGSQGFSGRSAVVSGSSR--MSCVAHSGGAGGGAYGFRSGAGGFGSRSLYNLGGNK 64
           ++     +GFS  SA + G SR   S V+ S   G G  G   G  GFGSRSLY LGG+K
Sbjct: 9   RSHSSSRRGFSANSARLPGVSRSGFSSVSVSRSRGSGGLGGACGGAGFGSRSLYGLGGSK 68

Query: 65  SISISVAAGGSRAGGFGGGRSSCAFAGGYGGGFGSGYG-GGFGGGFGGGRGMGGGFGGAG 123
            ISI            GGG  SCA +GGYG   G  YG GG G GFG G       GGAG
Sbjct: 69  RISI------------GGG--SCAISGGYGSRAGGSYGFGGAGSGFGFG-------GGAG 107

Query: 124 -GFGGAGGFGGAGGFGGPGGFGGSGGFGGPGSLGSPGGFGPGGFPGGIQEVTINQSLLQP 182
            GFG  GG G AGGFGGPG                     P   PGGIQEVT+NQSLL P
Sbjct: 108 IGFGLGGGAGLAGGFGGPG--------------------FPVCPPGGIQEVTVNQSLLTP 147

Query: 183 LNVEIDPQIGQVKAQEREQIKTLNNKFASFIDKVRFLEQQNKVLETKWNLLQQQGTSSIS 242
           LN++IDP I +V+A+EREQIKTLNNKFASFIDKVRFLEQQNKVLETKW LLQ+QGT ++ 
Sbjct: 148 LNLQIDPTIQRVRAEEREQIKTLNNKFASFIDKVRFLEQQNKVLETKWTLLQEQGTKTV- 206

Query: 243 GTNNLEPLFENHINYLRSYLDNILGERGRLDSELKNMEDLVEDFKKKYEDEINKRTAAEN 302
              NLEPLFE +IN LR  LD+I+GERGRLDSEL+ M+DLVEDFK KYEDEINKRTAAEN
Sbjct: 207 -RQNLEPLFEQYINNLRRQLDSIVGERGRLDSELRGMQDLVEDFKNKYEDEINKRTAAEN 265

Query: 303 EFVTLKKDVDSAYMNKVELQAKVDALIDEIDFLRTLYDAELSQMQSHISDTSVVLSMDNN 362
           EFVTLKKDVD+AYMNKVELQAK D L DEI+FLR LYDAELSQMQ+HISDTSVVLSMDNN
Sbjct: 266 EFVTLKKDVDAAYMNKVELQAKADTLTDEINFLRALYDAELSQMQTHISDTSVVLSMDNN 325

Query: 363 RSLDLDSIIAEVRAQYEDIAQRSKAEAEALYQTKLGELQTTAGRHGDDLRNTKSEIIELN 422
           R+LDLDSIIAEV+AQYE+IAQRS+AEAE+ YQTK  ELQ TAGRHGDDLRNTK EI E+N
Sbjct: 326 RNLDLDSIIAEVKAQYEEIAQRSRAEAESWYQTKYEELQVTAGRHGDDLRNTKQEIAEIN 385

Query: 423 RMIQRLRAEIEGVKKQNANLQTAIAEAEQHGEMALKDANAKLQELQAALQQAKDDLARLL 482
           RMIQRLR+EI+ VKKQ ANLQ AIA+AEQ GEMALKDA  KL+ L+ ALQ+AK DLARLL
Sbjct: 386 RMIQRLRSEIDHVKKQCANLQAAIADAEQRGEMALKDAKNKLEGLEDALQKAKQDLARLL 445

Query: 483 RDYQELMNVKLALDVEIATYRKLLEGEEYRMSGECPSAVSISVVSSSTTSASAGGYGGGY 542
           ++YQELMNVKLALDVEIATYRKLLEGEE R++GE    V+ISVV S+ +S    GYGG  
Sbjct: 446 KEYQELMNVKLALDVEIATYRKLLEGEECRLNGEGVGQVNISVVQSTVSS----GYGGAS 501

Query: 543 GGGMGGGLGGGFSAGGGSGSGFGRGGGGGIGGGFGGGSSGFSGGS 587
           G G G GLGGG S   GSG G G G     G   GGG S   GGS
Sbjct: 502 GVGSGLGLGGGSSYSYGSGLGVGGGFSSSSGRAIGGGLSSVGGGS 546



 Score = 54.7 bits (130), Expect = 3e-07
 Identities = 42/113 (37%), Positives = 51/113 (45%), Gaps = 26/113 (23%)

Query: 503 RKLLEGEEYRMSGECPSAVSISVVSSSTTSASAGGYGGGYGGG--------------MGG 548
           R+       R+ G   S  S   VS S  S   GG  GG G G              +GG
Sbjct: 15  RRGFSANSARLPGVSRSGFSSVSVSRSRGSGGLGGACGGAGFGSRSLYGLGGSKRISIGG 74

Query: 549 G---LGGGFSAG-------GGSGSGFGRGGGGGIGGGFGGGS--SGFSGGSGF 589
           G   + GG+ +        GG+GSGFG GGG GIG G GGG+  +G  GG GF
Sbjct: 75  GSCAISGGYGSRAGGSYGFGGAGSGFGFGGGAGIGFGLGGGAGLAGGFGGPGF 127



 Score = 37.0 bits (84), Expect = 0.055
 Identities = 39/111 (35%), Positives = 46/111 (41%), Gaps = 20/111 (18%)

Query: 525 VVSSSTTSASAGGYGGGYGGG---MGGGLGGGFSAGGGSGSGFGRGGGGGI--GGGFG-- 577
           + S+STT  S      G+      + G    GFS+   S S  G GG GG   G GFG  
Sbjct: 1   MASTSTTIRSHSSSRRGFSANSARLPGVSRSGFSSVSVSRSR-GSGGLGGACGGAGFGSR 59

Query: 578 -----GGSSGFS--GGS-----GFGSISGARYGVSGGGFSSASNRGGSIKF 616
                GGS   S  GGS     G+GS +G  YG  G G       G  I F
Sbjct: 60  SLYGLGGSKRISIGGGSCAISGGYGSRAGGSYGFGGAGSGFGFGGGAGIGF 110


>gi|119703753 keratin 6B [Homo sapiens]
          Length = 564

 Score =  678 bits (1750), Expect = 0.0
 Identities = 384/585 (65%), Positives = 428/585 (73%), Gaps = 51/585 (8%)

Query: 7   KTSGGGSQGFSGRSAVVSGSSR--MSCVAHSGGAGGGAYGFRSGAGGFGSRSLYNLGGNK 64
           ++     +GFS  SA + G SR   S ++ S   G G  G   G  GFGSRSLY LGG+K
Sbjct: 9   RSHSSSRRGFSANSARLPGVSRSGFSSISVSRSRGSGGLGGACGGAGFGSRSLYGLGGSK 68

Query: 65  SISISVAAGGSRAGGFGGGRSSCAFAGGYGGGFGSGYG-GGFGGGFGGGRGMGGGFGGAG 123
            ISI            GGG  SCA +GGYG   G  YG GG G GFG G       GGAG
Sbjct: 69  RISI------------GGG--SCAISGGYGSRAGGSYGFGGAGSGFGFG-------GGAG 107

Query: 124 -GFGGAGGFGGAGGFGGPGGFGGSGGFGGPGSLGSPGGFGPGGFPGGIQEVTINQSLLQP 182
            GFG  GG G AGGFGGPG                     P   PGGIQEVT+NQSLL P
Sbjct: 108 IGFGLGGGAGLAGGFGGPG--------------------FPVCPPGGIQEVTVNQSLLTP 147

Query: 183 LNVEIDPQIGQVKAQEREQIKTLNNKFASFIDKVRFLEQQNKVLETKWNLLQQQGTSSIS 242
           LN++IDP I +V+A+EREQIKTLNNKFASFIDKVRFLEQQNKVL+TKW LLQ+QGT ++ 
Sbjct: 148 LNLQIDPAIQRVRAEEREQIKTLNNKFASFIDKVRFLEQQNKVLDTKWTLLQEQGTKTV- 206

Query: 243 GTNNLEPLFENHINYLRSYLDNILGERGRLDSELKNMEDLVEDFKKKYEDEINKRTAAEN 302
              NLEPLFE +IN LR  LDNI+GERGRLDSEL+NM+DLVED K KYEDEINKRTAAEN
Sbjct: 207 -RQNLEPLFEQYINNLRRQLDNIVGERGRLDSELRNMQDLVEDLKNKYEDEINKRTAAEN 265

Query: 303 EFVTLKKDVDSAYMNKVELQAKVDALIDEIDFLRTLYDAELSQMQSHISDTSVVLSMDNN 362
           EFVTLKKDVD+AYMNKVELQAK D L DEI+FLR LYDAELSQMQ+HISDTSVVLSMDNN
Sbjct: 266 EFVTLKKDVDAAYMNKVELQAKADTLTDEINFLRALYDAELSQMQTHISDTSVVLSMDNN 325

Query: 363 RSLDLDSIIAEVRAQYEDIAQRSKAEAEALYQTKLGELQTTAGRHGDDLRNTKSEIIELN 422
           R+LDLDSIIAEV+AQYE+IAQRS+AEAE+ YQTK  ELQ TAGRHGDDLRNTK EI E+N
Sbjct: 326 RNLDLDSIIAEVKAQYEEIAQRSRAEAESWYQTKYEELQITAGRHGDDLRNTKQEIAEIN 385

Query: 423 RMIQRLRAEIEGVKKQNANLQTAIAEAEQHGEMALKDANAKLQELQAALQQAKDDLARLL 482
           RMIQRLR+EI+ VKKQ ANLQ AIA+AEQ GEMALKDA  KL+ L+ ALQ+AK DLARLL
Sbjct: 386 RMIQRLRSEIDHVKKQCANLQAAIADAEQRGEMALKDAKNKLEGLEDALQKAKQDLARLL 445

Query: 483 RDYQELMNVKLALDVEIATYRKLLEGEEYRMSGECPSAVSISVVSSSTTSASAGGYGGGY 542
           ++YQELMNVKLALDVEIATYRKLLEGEE R++GE    V+ISVV S+ +S    GYGG  
Sbjct: 446 KEYQELMNVKLALDVEIATYRKLLEGEECRLNGEGVGQVNISVVQSTVSS----GYGGAS 501

Query: 543 GGGMGGGLGGGFSAGGGSGSGFGRGGGGGIGGGFGGGSSGFSGGS 587
           G G G GLGGG S   GSG G G G     G   GGG S   GGS
Sbjct: 502 GVGSGLGLGGGSSYSYGSGLGVGGGFSSSSGRATGGGLSSVGGGS 546



 Score = 54.7 bits (130), Expect = 3e-07
 Identities = 42/113 (37%), Positives = 51/113 (45%), Gaps = 26/113 (23%)

Query: 503 RKLLEGEEYRMSGECPSAVSISVVSSSTTSASAGGYGGGYGGG--------------MGG 548
           R+       R+ G   S  S   VS S  S   GG  GG G G              +GG
Sbjct: 15  RRGFSANSARLPGVSRSGFSSISVSRSRGSGGLGGACGGAGFGSRSLYGLGGSKRISIGG 74

Query: 549 G---LGGGFSAG-------GGSGSGFGRGGGGGIGGGFGGGS--SGFSGGSGF 589
           G   + GG+ +        GG+GSGFG GGG GIG G GGG+  +G  GG GF
Sbjct: 75  GSCAISGGYGSRAGGSYGFGGAGSGFGFGGGAGIGFGLGGGAGLAGGFGGPGF 127



 Score = 36.6 bits (83), Expect = 0.072
 Identities = 39/111 (35%), Positives = 46/111 (41%), Gaps = 20/111 (18%)

Query: 525 VVSSSTTSASAGGYGGGYGGG---MGGGLGGGFSAGGGSGSGFGRGGGGGI--GGGFG-- 577
           + S+STT  S      G+      + G    GFS+   S S  G GG GG   G GFG  
Sbjct: 1   MASTSTTIRSHSSSRRGFSANSARLPGVSRSGFSSISVSRSR-GSGGLGGACGGAGFGSR 59

Query: 578 -----GGSSGFS--GGS-----GFGSISGARYGVSGGGFSSASNRGGSIKF 616
                GGS   S  GGS     G+GS +G  YG  G G       G  I F
Sbjct: 60  SLYGLGGSKRISIGGGSCAISGGYGSRAGGSYGFGGAGSGFGFGGGAGIGF 110


>gi|155969697 keratin 6C [Homo sapiens]
          Length = 564

 Score =  675 bits (1742), Expect = 0.0
 Identities = 381/585 (65%), Positives = 428/585 (73%), Gaps = 51/585 (8%)

Query: 7   KTSGGGSQGFSGRSAVVSGSSR--MSCVAHSGGAGGGAYGFRSGAGGFGSRSLYNLGGNK 64
           ++     +GFS  SA + G SR   S ++ S   G G  G   G  GFGSRSLY LGG+K
Sbjct: 9   RSHSSSRRGFSANSARLPGVSRSGFSSISVSRSRGSGGLGGACGGAGFGSRSLYGLGGSK 68

Query: 65  SISISVAAGGSRAGGFGGGRSSCAFAGGYGGGFGSGYG-GGFGGGFGGGRGMGGGFGGAG 123
            ISI            GGG  SCA +GGYG   G  YG GG G GFG G       GGAG
Sbjct: 69  RISI------------GGG--SCAISGGYGSRAGGSYGFGGAGSGFGFG-------GGAG 107

Query: 124 -GFGGAGGFGGAGGFGGPGGFGGSGGFGGPGSLGSPGGFGPGGFPGGIQEVTINQSLLQP 182
            GFG  GG G AGGFGGPG                     P   PGGIQEVT+NQSLL P
Sbjct: 108 IGFGLGGGAGLAGGFGGPG--------------------FPVCPPGGIQEVTVNQSLLTP 147

Query: 183 LNVEIDPQIGQVKAQEREQIKTLNNKFASFIDKVRFLEQQNKVLETKWNLLQQQGTSSIS 242
           LN++IDP I +V+A+EREQIKTLNNKFASFIDKVRFLEQQNKVL+TKW LLQ+QGT ++ 
Sbjct: 148 LNLQIDPAIQRVRAEEREQIKTLNNKFASFIDKVRFLEQQNKVLDTKWTLLQEQGTKTV- 206

Query: 243 GTNNLEPLFENHINYLRSYLDNILGERGRLDSELKNMEDLVEDFKKKYEDEINKRTAAEN 302
              NLEPLFE +IN LR  LD+I+GERGRLDSEL+NM+DLVED K KYEDEINKRTAAEN
Sbjct: 207 -RQNLEPLFEQYINNLRRQLDSIVGERGRLDSELRNMQDLVEDLKNKYEDEINKRTAAEN 265

Query: 303 EFVTLKKDVDSAYMNKVELQAKVDALIDEIDFLRTLYDAELSQMQSHISDTSVVLSMDNN 362
           EFVTLKKDVD+AYMNKVELQAK D L DEI+FLR LYDAELSQMQ+HISDTSVVLSMDNN
Sbjct: 266 EFVTLKKDVDAAYMNKVELQAKADTLTDEINFLRALYDAELSQMQTHISDTSVVLSMDNN 325

Query: 363 RSLDLDSIIAEVRAQYEDIAQRSKAEAEALYQTKLGELQTTAGRHGDDLRNTKSEIIELN 422
           R+LDLDSIIAEV+AQYE+IAQRS+AEAE+ YQTK  ELQ TAGRHGDDLRNTK EI E+N
Sbjct: 326 RNLDLDSIIAEVKAQYEEIAQRSRAEAESWYQTKYEELQVTAGRHGDDLRNTKQEIAEIN 385

Query: 423 RMIQRLRAEIEGVKKQNANLQTAIAEAEQHGEMALKDANAKLQELQAALQQAKDDLARLL 482
           RMIQRLR+EI+ VKKQ A+LQ AIA+AEQ GEMALKDA  KL+ L+ ALQ+AK DLARLL
Sbjct: 386 RMIQRLRSEIDHVKKQCASLQAAIADAEQRGEMALKDAKNKLEGLEDALQKAKQDLARLL 445

Query: 483 RDYQELMNVKLALDVEIATYRKLLEGEEYRMSGECPSAVSISVVSSSTTSASAGGYGGGY 542
           ++YQELMNVKLALDVEIATYRKLLEGEE R++GE    V++SVV S+ +S    GYGG  
Sbjct: 446 KEYQELMNVKLALDVEIATYRKLLEGEECRLNGEGVGQVNVSVVQSTISS----GYGGAS 501

Query: 543 GGGMGGGLGGGFSAGGGSGSGFGRGGGGGIGGGFGGGSSGFSGGS 587
           G G G GLGGG S   GSG G G G     G   GGG S   GGS
Sbjct: 502 GVGSGLGLGGGSSYSYGSGLGIGGGFSSSSGRAIGGGLSSVGGGS 546



 Score = 54.7 bits (130), Expect = 3e-07
 Identities = 42/113 (37%), Positives = 51/113 (45%), Gaps = 26/113 (23%)

Query: 503 RKLLEGEEYRMSGECPSAVSISVVSSSTTSASAGGYGGGYGGG--------------MGG 548
           R+       R+ G   S  S   VS S  S   GG  GG G G              +GG
Sbjct: 15  RRGFSANSARLPGVSRSGFSSISVSRSRGSGGLGGACGGAGFGSRSLYGLGGSKRISIGG 74

Query: 549 G---LGGGFSAG-------GGSGSGFGRGGGGGIGGGFGGGS--SGFSGGSGF 589
           G   + GG+ +        GG+GSGFG GGG GIG G GGG+  +G  GG GF
Sbjct: 75  GSCAISGGYGSRAGGSYGFGGAGSGFGFGGGAGIGFGLGGGAGLAGGFGGPGF 127



 Score = 36.6 bits (83), Expect = 0.072
 Identities = 39/111 (35%), Positives = 46/111 (41%), Gaps = 20/111 (18%)

Query: 525 VVSSSTTSASAGGYGGGYGGG---MGGGLGGGFSAGGGSGSGFGRGGGGGI--GGGFG-- 577
           + S+STT  S      G+      + G    GFS+   S S  G GG GG   G GFG  
Sbjct: 1   MASTSTTIRSHSSSRRGFSANSARLPGVSRSGFSSISVSRSR-GSGGLGGACGGAGFGSR 59

Query: 578 -----GGSSGFS--GGS-----GFGSISGARYGVSGGGFSSASNRGGSIKF 616
                GGS   S  GGS     G+GS +G  YG  G G       G  I F
Sbjct: 60  SLYGLGGSKRISIGGGSCAISGGYGSRAGGSYGFGGAGSGFGFGGGAGIGF 110


>gi|109255249 keratin 4 [Homo sapiens]
          Length = 594

 Score =  640 bits (1652), Expect = 0.0
 Identities = 363/560 (64%), Positives = 416/560 (74%), Gaps = 71/560 (12%)

Query: 11  GGSQGFSGRSAVVSGSSR--MSCVAHSGGAGGGAYGFRSGAGGFGSRSLYNLGGNKSISI 68
           GG +GFS  SA+V G  R   S V+ SGGAG      R  +GGFGSRSLYNL GNKSIS+
Sbjct: 84  GGPRGFSCGSAIVGGGKRGAFSSVSMSGGAG------RCSSGGFGSRSLYNLRGNKSISM 137

Query: 69  SVAAGGSRAGGFGGGRSSCAFAGGYGGGFGSGYGGGFGGGFGGGRGMGGGFGGAGGFGGA 128
           SVA  GSR G   GG      AGG+G G   G+GGGFGG F G                 
Sbjct: 138 SVA--GSRQGACFGG------AGGFGTG---GFGGGFGGSFSGK---------------- 170

Query: 129 GGFGGAGGFGGPGGFGGSGGFGGPGSLGSPGGFGPGGFPGGIQEVTINQSLLQPLNVEID 188
                                GGPG    P         GGIQEVTINQSLL PL+VEID
Sbjct: 171 ---------------------GGPGFPVCPA--------GGIQEVTINQSLLTPLHVEID 201

Query: 189 PQIGQVKAQEREQIKTLNNKFASFIDKVRFLEQQNKVLETKWNLLQQQGTSSISGTNNLE 248
           P+I +V+ +EREQIK LNNKFASFIDKV+FLEQQNKVLETKWNLLQQQ T++ S   NLE
Sbjct: 202 PEIQKVRTEEREQIKLLNNKFASFIDKVQFLEQQNKVLETKWNLLQQQTTTTSS--KNLE 259

Query: 249 PLFENHINYLRSYLDNILGERGRLDSELKNMEDLVEDFKKKYEDEINKRTAAENEFVTLK 308
           PLFE +++ LR  LD +  ++GRL SELK M+D VEDFK KYE+EINKRTAAEN+FV LK
Sbjct: 260 PLFETYLSVLRKQLDTLGNDKGRLQSELKTMQDSVEDFKTKYEEEINKRTAAENDFVVLK 319

Query: 309 KDVDSAYMNKVELQAKVDALIDEIDFLRTLYDAELSQMQSHISDTSVVLSMDNNRSLDLD 368
           KDVD+AY+NKVEL+AKVD+L DEI+FL+ LYDAELSQMQ+H+SDTSVVLSMDNNR+LDLD
Sbjct: 320 KDVDAAYLNKVELEAKVDSLNDEINFLKVLYDAELSQMQTHVSDTSVVLSMDNNRNLDLD 379

Query: 369 SIIAEVRAQYEDIAQRSKAEAEALYQTKLGELQTTAGRHGDDLRNTKSEIIELNRMIQRL 428
           SIIAEVRAQYE+IAQRSKAEAEALYQTK+ +LQ +  +HGD+L+NTKSEI ELNRMIQRL
Sbjct: 380 SIIAEVRAQYEEIAQRSKAEAEALYQTKVQQLQISVDQHGDNLKNTKSEIAELNRMIQRL 439

Query: 429 RAEIEGVKKQNANLQTAIAEAEQHGEMALKDANAKLQELQAALQQAKDDLARLLRDYQEL 488
           RAEIE +KKQ   LQ ++A+AEQ GE ALKDA++K  EL+AALQQAK++LAR+LR+YQEL
Sbjct: 440 RAEIENIKKQCQTLQVSVADAEQRGENALKDAHSKRVELEAALQQAKEELARMLREYQEL 499

Query: 489 MNVKLALDVEIATYRKLLEGEEYRMSGECPSAVSISVVSSSTTSASAGGYGGGYGGGMGG 548
           M+VKLALD+EIATYRKLLEGEEYRMSGEC SAVSISVVS ST   S GG  GG G G G 
Sbjct: 500 MSVKLALDIEIATYRKLLEGEEYRMSGECQSAVSISVVSGST---STGGISGGLGSGSGF 556

Query: 549 GLGGGFSAGGGSGSGFGRGG 568
           GL  GF  G GSGSGFG GG
Sbjct: 557 GLSSGF--GSGSGSGFGFGG 574



 Score =  615 bits (1585), Expect = e-176
 Identities = 344/516 (66%), Positives = 396/516 (76%), Gaps = 27/516 (5%)

Query: 61  GGNKSISI-SVAAGGSRAGGFGGGRSSCAFAGGYG----GGFGSGYGGGFGGGFGGGRGM 115
           GG +  S  S   GG + G F    SS + +GG G    GGFGS       G       +
Sbjct: 84  GGPRGFSCGSAIVGGGKRGAF----SSVSMSGGAGRCSSGGFGSRSLYNLRGNKSISMSV 139

Query: 116 GGGFGGAGGFGGAGGFGGAGGFGGPGGFGGS-GGFGGPGSLGSPGGFGPGGFPGGIQEVT 174
            G   GA  FGGAGGFG  GGFGG  GFGGS  G GGPG    P G        GIQEVT
Sbjct: 140 AGSRQGAC-FGGAGGFG-TGGFGG--GFGGSFSGKGGPGFPVCPAG--------GIQEVT 187

Query: 175 INQSLLQPLNVEIDPQIGQVKAQEREQIKTLNNKFASFIDKVRFLEQQNKVLETKWNLLQ 234
           INQSLL PL+VEIDP+I +V+ +EREQIK LNNKFASFIDKV+FLEQQNKVLETKWNLLQ
Sbjct: 188 INQSLLTPLHVEIDPEIQKVRTEEREQIKLLNNKFASFIDKVQFLEQQNKVLETKWNLLQ 247

Query: 235 QQGTSSISGTNNLEPLFENHINYLRSYLDNILGERGRLDSELKNMEDLVEDFKKKYEDEI 294
           QQ T++ S   NLEPLFE +++ LR  LD +  ++GRL SELK M+D VEDFK KYE+EI
Sbjct: 248 QQTTTTSS--KNLEPLFETYLSVLRKQLDTLGNDKGRLQSELKTMQDSVEDFKTKYEEEI 305

Query: 295 NKRTAAENEFVTLKKDVDSAYMNKVELQAKVDALIDEIDFLRTLYDAELSQMQSHISDTS 354
           NKRTAAEN+FV LKKDVD+AY+NKVEL+AKVD+L DEI+FL+ LYDAELSQMQ+H+SDTS
Sbjct: 306 NKRTAAENDFVVLKKDVDAAYLNKVELEAKVDSLNDEINFLKVLYDAELSQMQTHVSDTS 365

Query: 355 VVLSMDNNRSLDLDSIIAEVRAQYEDIAQRSKAEAEALYQTKLGELQTTAGRHGDDLRNT 414
           VVLSMDNNR+LDLDSIIAEVRAQYE+IAQRSKAEAEALYQTK+ +LQ +  +HGD+L+NT
Sbjct: 366 VVLSMDNNRNLDLDSIIAEVRAQYEEIAQRSKAEAEALYQTKVQQLQISVDQHGDNLKNT 425

Query: 415 KSEIIELNRMIQRLRAEIEGVKKQNANLQTAIAEAEQHGEMALKDANAKLQELQAALQQA 474
           KSEI ELNRMIQRLRAEIE +KKQ   LQ ++A+AEQ GE ALKDA++K  EL+AALQQA
Sbjct: 426 KSEIAELNRMIQRLRAEIENIKKQCQTLQVSVADAEQRGENALKDAHSKRVELEAALQQA 485

Query: 475 KDDLARLLRDYQELMNVKLALDVEIATYRKLLEGEEYRMSGECPSAVSISVVSSSTTSAS 534
           K++LAR+LR+YQELM+VKLALD+EIATYRKLLEGEEYRMSGEC SAVSISVVS ST   S
Sbjct: 486 KEELARMLREYQELMSVKLALDIEIATYRKLLEGEEYRMSGECQSAVSISVVSGST---S 542

Query: 535 AGGYGGGYGGGMGGGLGGGFSAGGGSGSGFGRGGGG 570
            GG  GG G G G GL  GF +G GSG GFG    G
Sbjct: 543 TGGISGGLGSGSGFGLSSGFGSGSGSGFGFGGSVSG 578



 Score = 38.1 bits (87), Expect = 0.025
 Identities = 33/113 (29%), Positives = 43/113 (38%), Gaps = 15/113 (13%)

Query: 515 GECPSAVSISVVSSSTTSASAGGYGGGYGGGMGGGLGGGFSAGGGSGSGFGRGGGGGIGG 574
           G   S ++ S +S++  +      GG  G   G  + GG   G  S      G G    G
Sbjct: 60  GPVTSLIAPSSLSAAMIARQQCVRGGPRGFSCGSAIVGGGKRGAFSSVSMSGGAGRCSSG 119

Query: 575 GFGGGS--------------SGFSGGSGFGSISGARYGVSGGGF-SSASNRGG 612
           GFG  S              +G   G+ FG   G   G  GGGF  S S +GG
Sbjct: 120 GFGSRSLYNLRGNKSISMSVAGSRQGACFGGAGGFGTGGFGGGFGGSFSGKGG 172



 Score = 37.0 bits (84), Expect = 0.055
 Identities = 29/73 (39%), Positives = 33/73 (45%), Gaps = 3/73 (4%)

Query: 520 AVSISVVSSSTTSASAGGYGGGYGGGMGGGLGGGFSAGGGSGSGFGRGGGGGIG-GGFGG 578
           A S   +S      S+GG+G      + G      S  G S  G   GG GG G GGFGG
Sbjct: 103 AFSSVSMSGGAGRCSSGGFGSRSLYNLRGNKSISMSVAG-SRQGACFGGAGGFGTGGFGG 161

Query: 579 GSSG-FSGGSGFG 590
           G  G FSG  G G
Sbjct: 162 GFGGSFSGKGGPG 174



 Score = 35.4 bits (80), Expect = 0.16
 Identities = 28/79 (35%), Positives = 31/79 (39%), Gaps = 5/79 (6%)

Query: 536 GGYGGGYGG-GMGGGLGGGFSAGGGSGSGFGRGGGGGIGGGFGGGSSG--FSGGSGFGSI 592
           GG  G +    M GG G   S G GS S +   G   I     G   G  F G  GFG+ 
Sbjct: 98  GGKRGAFSSVSMSGGAGRCSSGGFGSRSLYNLRGNKSISMSVAGSRQGACFGGAGGFGT- 156

Query: 593 SGARYGVSGGGFSSASNRG 611
            G   G  GG FS     G
Sbjct: 157 -GGFGGGFGGSFSGKGGPG 174


>gi|153791158 keratin 75 [Homo sapiens]
          Length = 551

 Score =  613 bits (1580), Expect = e-175
 Identities = 362/630 (57%), Positives = 432/630 (68%), Gaps = 88/630 (13%)

Query: 1   MSRQASKTSGGGSQ-GFSGRSAVV--SGSSRMSCVAHS-GGAGGGAYGFRSGAGG-FGSR 55
           MSRQ+S T   GS+ GFS  SA+   +G SR S V+ +   AG G  G  S AG  FGSR
Sbjct: 1   MSRQSSITFQSGSRRGFSTTSAITPAAGRSRFSSVSVARSAAGSGGLGRISSAGASFGSR 60

Query: 56  SLYNLGGNKSISISVAAGGSRAGGFGGGRSSCAFAGGYGGGFGSGYGGGFGGGFGGGRGM 115
           SLYNLGG K +SI+                          G GS    GFGG      G+
Sbjct: 61  SLYNLGGAKRVSIN--------------------------GCGSSCRSGFGGRASNRFGV 94

Query: 116 GGGFGGAGGFGGAGGFGGAGGFGGPGGFGGSGGFGGPGSLGSPGGFGPGGFPGGIQEVTI 175
             GFG  GG G                    GGF GP     P        PGGIQEVT+
Sbjct: 95  NSGFGYGGGVG--------------------GGFSGPSFPVCP--------PGGIQEVTV 126

Query: 176 NQSLLQPLNVEIDPQIGQVKAQEREQIKTLNNKFASFIDKVRFLEQQNKVLETKWNLLQQ 235
           NQSLL PL+++IDP I +V+A+EREQIKTLNNKFASFIDKVRFLEQQNKVLETKW LLQ+
Sbjct: 127 NQSLLTPLHLQIDPTIQRVRAEEREQIKTLNNKFASFIDKVRFLEQQNKVLETKWALLQE 186

Query: 236 QGTSSISGTNNLEPLFENHINYLRSYLDNILGERGRLDSELKNMEDLVEDFKKKYEDEIN 295
           QG+ ++    NLEPLF+++ + LR  L++I  ERGRL++EL+NM+D+VEDFK +YEDEIN
Sbjct: 187 QGSRTVR--QNLEPLFDSYTSELRRQLESITTERGRLEAELRNMQDVVEDFKVRYEDEIN 244

Query: 296 KRTAAENEFVTLKKDVDSAYMNKVELQAKVDALIDEIDFLRTLYDAELSQMQSHISDTSV 355
           KRTAAENEFV LKKDVD+AYMNKVEL+AKV +L +EI+F+ +++DAELSQ+Q+ + DTSV
Sbjct: 245 KRTAAENEFVALKKDVDAAYMNKVELEAKVKSLPEEINFIHSVFDAELSQLQTQVGDTSV 304

Query: 356 VLSMDNNRSLDLDSIIAEVRAQYEDIAQRSKAEAEALYQTKLGELQTTAGRHGDDLRNTK 415
           VLSMDNNR+LDLDSIIAEV+AQYEDIA RS+AEAE+ YQTK  ELQ TAGRHGDDLRNTK
Sbjct: 305 VLSMDNNRNLDLDSIIAEVKAQYEDIANRSRAEAESWYQTKYEELQVTAGRHGDDLRNTK 364

Query: 416 SEIIELNRMIQRLRAEIEGVKKQNANLQTAIAEAEQHGEMALKDANAKLQELQAALQQAK 475
            EI E+NRMIQRLRAEI+ VKKQ ++LQTAIA+AEQ GE+ALKDA AKL +L+ ALQ+AK
Sbjct: 365 QEISEMNRMIQRLRAEIDSVKKQCSSLQTAIADAEQRGELALKDARAKLVDLEEALQKAK 424

Query: 476 DDLARLLRDYQELMNVKLALDVEIATYRKLLEGEEYRMSGECPSAVSISVVSSSTTSASA 535
            D+ARLLR+YQELMN+KLALDVEIATYRKLLEGEE R+SGE  S V+ISVV+S+ +S   
Sbjct: 425 QDMARLLREYQELMNIKLALDVEIATYRKLLEGEECRLSGEGVSPVNISVVTSTLSS--- 481

Query: 536 GGYGGGYGGGMGGGLGGGFSAGGGSGSGFGRGGGGGIGGGFGGGSSGFSGGSGFGSISGA 595
                GYG G   G GG    GGGSG  F   GG  +G G GG  SGFS  S  G     
Sbjct: 482 -----GYGSGSSIG-GGNLGLGGGSGYSFTTSGGHSLGAGLGG--SGFSATSNRG----- 528

Query: 596 RYGVSGGGFSSASNRGGSIKFSQSSQSSQR 625
                GG        G S+KF  ++ SSQ+
Sbjct: 529 ----LGGS-------GSSVKFVSTTSSSQK 547


>gi|194018511 keratin 77 [Homo sapiens]
          Length = 578

 Score =  609 bits (1571), Expect = e-174
 Identities = 353/597 (59%), Positives = 424/597 (71%), Gaps = 57/597 (9%)

Query: 1   MSRQASKTSGGGSQGFSGRSAVVSGSSRMSCVAHSGG-AGGGAYGFRSGAGGFGSRSLYN 59
           MSR+   TS     G         GS  +  V ++ G  GGG YG      GFGSRSLYN
Sbjct: 14  MSRRVYSTSSSAGSG--------GGSPAVGSVCYARGRCGGGGYGIHGR--GFGSRSLYN 63

Query: 60  LGGNKSISISVAAGGSRAGGFGGGRSSCAFAGGYGGGFGSGYGGGFGGGFGGGRGMGGGF 119
           LGG++SISI++            GRS+  F    GGG      GGFGGG    RG G G 
Sbjct: 64  LGGSRSISINLM-----------GRSTSGFC--QGGGV-----GGFGGG----RGFGVGS 101

Query: 120 GGAGGFGGAGGFGGAGGFGGPGGFGGSGGFGGPGSLGSPGGFGPGGFPGGIQEVTINQSL 179
            GAGGFGG GGFGGAG         G+  FG        GGFGP   PGGIQEVTINQSL
Sbjct: 102 TGAGGFGG-GGFGGAG--------FGTSNFG-------LGGFGPYCPPGGIQEVTINQSL 145

Query: 180 LQPLNVEIDPQIGQVKAQEREQIKTLNNKFASFIDKVRFLEQQNKVLETKWNLLQQQGTS 239
           L+PL++E+DP+I ++K QEREQI  LNNKFASFIDKVRFLEQQN+VL+TKW LLQQ  TS
Sbjct: 146 LEPLHLEVDPEIQRIKTQEREQIMVLNNKFASFIDKVRFLEQQNQVLQTKWELLQQVNTS 205

Query: 240 SISGTNNLEPLFENHINYLRSYLDNILGERGRLDSELKNMEDLVEDFKKKYEDEINKRTA 299
             +GTNNLEPL EN+I  LR  +D +  E+ R ++E+++M+D+VED+K KYEDEINKRT 
Sbjct: 206 --TGTNNLEPLLENYIGDLRRQVDLLSAEQMRQNAEVRSMQDVVEDYKSKYEDEINKRTG 263

Query: 300 AENEFVTLKKDVDSAYMNKVELQAKVDALIDEIDFLRTLYDAELSQMQSHISDTSVVLSM 359
           +EN+FV LKKDVD+AY++KV+L+++VD L  E++FL+ L+  ELSQ+Q+HISDT+V+LSM
Sbjct: 264 SENDFVVLKKDVDAAYVSKVDLESRVDTLTGEVNFLKYLFLTELSQVQTHISDTNVILSM 323

Query: 360 DNNRSLDLDSIIAEVRAQYEDIAQRSKAEAEALYQTKLGELQTTAGRHGDDLRNTKSEII 419
           DNNRSLDLDSII  VR QYE IAQRSK EAEALYQTK  ELQ TAGRHGDDL+N+K EI 
Sbjct: 324 DNNRSLDLDSIIDAVRTQYELIAQRSKDEAEALYQTKYQELQITAGRHGDDLKNSKMEIA 383

Query: 420 ELNRMIQRLRAEIEGVKKQNANLQTAIAEAEQHGEMALKDANAKLQELQAALQQAKDDLA 479
           ELNR +QRL+AEI  VKKQ   +Q+ I++AE+ GE AL+DA  KLQ+L+ ALQQ+K++LA
Sbjct: 384 ELNRTVQRLQAEISNVKKQIEQMQSLISDAEERGEQALQDAWQKLQDLEEALQQSKEELA 443

Query: 480 RLLRDYQELMNVKLALDVEIATYRKLLEGEEYRMSGECPSAVSISVVSSS-TTSASAGGY 538
           RLLRDYQ ++ VKL+LDVEIATYR+LLEGEE RMSGE  S VSISV +S  + +  AGG 
Sbjct: 444 RLLRDYQAMLGVKLSLDVEIATYRQLLEGEESRMSGELQSHVSISVQNSQVSVNGGAGGG 503

Query: 539 G----GGYGGGMGGGLGGGFSAGGGSGSGFGRGGGGGIGGGFGGGSSGFSGGSGFGS 591
           G    GGYGGG GGG GGG S  GG   G   GGG G G G GGGS G SG SG GS
Sbjct: 504 GSYGSGGYGGGSGGGYGGGRSYRGGGARG-RSGGGYGSGCGGGGGSYGGSGRSGRGS 559



 Score = 55.8 bits (133), Expect = 1e-07
 Identities = 34/77 (44%), Positives = 38/77 (49%), Gaps = 2/77 (2%)

Query: 102 GGGFGGGFGGGRGMGGGFGGAGGFGGAGGFGGAGGFGGPGGFGGSGGFGGPGSLGSPGGF 161
           GG  GGG  G  G GGG GG  G+GG   + G G  G  GG  GSG  GG GS G  G  
Sbjct: 498 GGAGGGGSYGSGGYGGGSGG--GYGGGRSYRGGGARGRSGGGYGSGCGGGGGSYGGSGRS 555

Query: 162 GPGGFPGGIQEVTINQS 178
           G G     I + + N S
Sbjct: 556 GRGSSRVQIIQTSTNTS 572



 Score = 47.0 bits (110), Expect = 5e-05
 Identities = 36/91 (39%), Positives = 42/91 (46%), Gaps = 14/91 (15%)

Query: 23  VSGSSRMSCVAHSGGAGGGAYGFRSGAGGFGSRSLYNLGGNKSISISVAAGGSRAGGFGG 82
           VS S + S V+ +GGAGGG      G+GG+G  S    GG          G S  GG   
Sbjct: 485 VSISVQNSQVSVNGGAGGGG---SYGSGGYGGGSGGGYGG----------GRSYRGGGAR 531

Query: 83  GRSSCAFAGGYGGGFGSGYGGGFGGGFGGGR 113
           GRS   +  G GGG G  YGG    G G  R
Sbjct: 532 GRSGGGYGSGCGGG-GGSYGGSGRSGRGSSR 561



 Score = 44.3 bits (103), Expect = 3e-04
 Identities = 38/115 (33%), Positives = 44/115 (38%), Gaps = 20/115 (17%)

Query: 513 MSGECPSAVSISVVSSSTTSASAGGYGGGYGGGMGGGLGGGFSAGGGSGSGFGRGGGG-- 570
           MS +  S  + S +S    S S+    GG    +G         GGG     GRG G   
Sbjct: 1   MSHQFSSQSAFSSMSRRVYSTSSSAGSGGGSPAVGSVCYARGRCGGGGYGIHGRGFGSRS 60

Query: 571 --GIGG--------------GF--GGGSSGFSGGSGFGSISGARYGVSGGGFSSA 607
              +GG              GF  GGG  GF GG GFG  S    G  GGGF  A
Sbjct: 61  LYNLGGSRSISINLMGRSTSGFCQGGGVGGFGGGRGFGVGSTGAGGFGGGGFGGA 115


>gi|32567786 keratin 6L [Homo sapiens]
          Length = 535

 Score =  580 bits (1494), Expect = e-165
 Identities = 343/580 (59%), Positives = 392/580 (67%), Gaps = 71/580 (12%)

Query: 1   MSRQASKTSGGGSQ----GFSGRSAVVSGSSRMSCVAHSGGAGGGAYGFRSGAGGFGSRS 56
           +SRQ   T GG S     G SG  A  S SS    V+ S G+GGGA+    G GGFGSRS
Sbjct: 5   VSRQTYSTKGGFSSNSASGGSGSQARTSFSS--VTVSRSSGSGGGAH-CGPGTGGFGSRS 61

Query: 57  LYNLGGNKSISISVAAGGSRAGGFGGGRSSCAFAGGYGGGFGSGYGGGFGGGFGGGRGMG 116
           LYNLGG+KSIS+SVA G              A  G   GGF          GFG    MG
Sbjct: 62  LYNLGGHKSISVSVAGG--------------ALLGRALGGF----------GFGSRAFMG 97

Query: 117 GGFGGAGGFGGAGGFGGAGGFGGPGGFGGSGGFGGPGSLGSPGGFGPGGFPGGIQEVTIN 176
            G  G   FG A                             PGG         IQEVT+N
Sbjct: 98  QG-AGRQTFGPA---------------------------CPPGG---------IQEVTVN 120

Query: 177 QSLLQPLNVEIDPQIGQVKAQEREQIKTLNNKFASFIDKVRFLEQQNKVLETKWNLLQQQ 236
           QSLL PL+VEIDP+I +V+ QEREQIKTLNNKFASFIDKVRFLEQQNKVLETKW LLQ+Q
Sbjct: 121 QSLLTPLHVEIDPEIQRVRTQEREQIKTLNNKFASFIDKVRFLEQQNKVLETKWALLQEQ 180

Query: 237 GTSSISGTNNLEPLFENHINYLRSYLDNILGERGRLDSELKNMEDLVEDFKKKYEDEINK 296
           G +     NNLEPLFE ++  +RS LD +  ERGRLDSEL+N++DLVEDFK KYEDEINK
Sbjct: 181 GQNLGVTRNNLEPLFEAYLGSMRSTLDRLQSERGRLDSELRNVQDLVEDFKNKYEDEINK 240

Query: 297 RTAAENEFVTLKKDVDSAYMNKVELQAKVDALIDEIDFLRTLYDAELSQMQSHISDTSVV 356
            TAAENEFV LKKDVD+AYM +++L  KV  L  EIDFL+ LY+ ELSQ+Q+H+S+T+VV
Sbjct: 241 HTAAENEFVVLKKDVDAAYMGRMDLHGKVGTLTQEIDFLQQLYEMELSQVQTHVSNTNVV 300

Query: 357 LSMDNNRSLDLDSIIAEVRAQYEDIAQRSKAEAEALYQTKLGELQTTAGRHGDDLRNTKS 416
           LSMDNNR+LDLDSIIAEV+AQYE IAQRS+AEAEA YQTK  ELQ TAG+HGD+LR+TK+
Sbjct: 301 LSMDNNRNLDLDSIIAEVKAQYELIAQRSRAEAEAWYQTKYEELQVTAGKHGDNLRDTKN 360

Query: 417 EIIELNRMIQRLRAEIEGVKKQNANLQTAIAEAEQHGEMALKDANAKLQELQAALQQAKD 476
           EI EL R IQRL+ E +  KKQ   LQTAIAEAEQ GE+ALKDA  KL +L  AL QAK+
Sbjct: 361 EIAELTRTIQRLQGEADAAKKQCQQLQTAIAEAEQRGELALKDAQKKLGDLDVALHQAKE 420

Query: 477 DLARLLRDYQELMNVKLALDVEIATYRKLLEGEEYRMSGECPSAVSISVVSSSTTSASAG 536
           DL RLLRDYQELMNVKLALDVEIATYRKLLE EE RMSGECPSAVSISV  +STT    G
Sbjct: 421 DLTRLLRDYQELMNVKLALDVEIATYRKLLESEESRMSGECPSAVSISVTGNSTT--VCG 478

Query: 537 GYGGGYGGGMG-GGLGGGFSAGGGSGSGFGRGGGGGIGGG 575
           G    +GGG+  GG GG    G  +  G+    GG +  G
Sbjct: 479 GGAASFGGGISLGGSGGATKGGFSTNVGYSTVKGGPVSAG 518



 Score = 34.3 bits (77), Expect = 0.36
 Identities = 34/91 (37%), Positives = 37/91 (40%), Gaps = 7/91 (7%)

Query: 524 SVVSSSTTSASAGGYGGGYGGGMGGGLGGGFSA---GGGSGSGFGRGGGGGIGGGFGGGS 580
           S VS  T S   G       GG G      FS+      SGSG G   G G  GGFG  S
Sbjct: 3   SSVSRQTYSTKGGFSSNSASGGSGSQARTSFSSVTVSRSSGSGGGAHCGPGT-GGFGSRS 61

Query: 581 SGFSGGSGFGSIS---GARYGVSGGGFSSAS 608
               GG    S+S   GA  G + GGF   S
Sbjct: 62  LYNLGGHKSISVSVAGGALLGRALGGFGFGS 92


>gi|28173564 keratin 73 [Homo sapiens]
          Length = 540

 Score =  558 bits (1437), Expect = e-159
 Identities = 331/597 (55%), Positives = 402/597 (67%), Gaps = 80/597 (13%)

Query: 1   MSRQASKTSGGGSQG-FSGRSAVVSGSSRMSCVAHSGGAGGGAYGFRSGAGGFGSRSLYN 59
           MSRQ +  SG  ++G FSG SAV+SG S  S  A  GG G         +GGF SRSLY+
Sbjct: 1   MSRQFTYKSGAAAKGGFSGCSAVLSGGSSSSYRA--GGKGL--------SGGFSSRSLYS 50

Query: 60  LGGNKSISISVAAGGSRAGGFGGGRSSCAFAGGYGGGFGSGYGGGFGGGFGGGRGMGGGF 119
           LGG +SIS +VA+G   AGG+               GFG G   GF G   G   +G   
Sbjct: 51  LGGARSISFNVASGSGWAGGY---------------GFGRGRASGFAGSMFGSVALGSVC 95

Query: 120 GGAGGFGGAGGFGGAGGFGGPGGFGGSGGFGGPGSLGSPGGFGPGGFPGGIQEVTINQSL 179
                                             SL  P         GGI +VTIN+SL
Sbjct: 96  ---------------------------------PSLCPP---------GGIHQVTINKSL 113

Query: 180 LQPLNVEIDPQIGQVKAQEREQIKTLNNKFASFIDKVRFLEQQNKVLETKWNLLQQQGTS 239
           L PLNVE+DP+I +V+AQEREQIK LNNKFASFIDKVRFLEQQN+VLETKW LLQQ   +
Sbjct: 114 LAPLNVELDPEIQKVRAQEREQIKVLNNKFASFIDKVRFLEQQNQVLETKWELLQQLDLN 173

Query: 240 SISGTNNLEPLFENHINYLRSYLDNILGERGRLDSELKNMEDLVEDFKKKYEDEINKRTA 299
           +    NNLEP+ E +I+ LR  L+ + G+R RLDSEL+++ ++VED+KK+YE+EINKRT 
Sbjct: 174 NCK--NNLEPILEGYISNLRKQLETLSGDRVRLDSELRSVREVVEDYKKRYEEEINKRTT 231

Query: 300 AENEFVTLKKDVDSAYMNKVELQAKVDALIDEIDFLRTLYDAELSQMQSHISDTSVVLSM 359
           AENEFV LKKDVD+AY +KVELQAKVDAL  EI F + LY+ E +Q+QSHISDTS++LSM
Sbjct: 232 AENEFVVLKKDVDAAYTSKVELQAKVDALDGEIKFFKCLYEGETAQIQSHISDTSIILSM 291

Query: 360 DNNRSLDLDSIIAEVRAQYEDIAQRSKAEAEALYQTKLGELQTTAGRHGDDLRNTKSEII 419
           DNNR+LDLDSIIAEVRAQYE+IA++SKAEAEALYQTK  ELQ  AGRHGDDL++TK+EI 
Sbjct: 292 DNNRNLDLDSIIAEVRAQYEEIARKSKAEAEALYQTKFQELQLAAGRHGDDLKHTKNEIS 351

Query: 420 ELNRMIQRLRAEIEGVKKQNANLQTAIAEAEQHGEMALKDANAKLQELQAALQQAKDDLA 479
           EL R+IQRLR+EIE VKKQ ANL+TAIA+AEQ G+ ALKDA AKL EL+ ALQQAK++LA
Sbjct: 352 ELTRLIQRLRSEIESVKKQCANLETAIADAEQRGDCALKDARAKLDELEGALQQAKEELA 411

Query: 480 RLLRDYQELMNVKLALDVEIATYRKLLEGEEYRMSGECPSAVSISVVSSSTTSASAGGYG 539
           R+LR+YQEL++VKL+LD+EIATYRKLLEGEE RMSGE  ++VSISV++SS   A   G G
Sbjct: 412 RMLREYQELLSVKLSLDIEIATYRKLLEGEECRMSGEYTNSVSISVINSS--MAGMAGTG 469

Query: 540 GGYGGGMGGGLG-------GGFS-AGGGSGSGFGRGGGGGIGGGFGGGSSGFSGGSG 588
            G+G    G  G       GG+S   GG  +G G     G      G +S F    G
Sbjct: 470 AGFGFSNAGTYGYWPSSVSGGYSMLPGGCVTGSGNCSPRGEARTRLGSASEFRDSQG 526



 Score = 38.5 bits (88), Expect = 0.019
 Identities = 30/82 (36%), Positives = 39/82 (47%), Gaps = 22/82 (26%)

Query: 532 SASAGGYGG-----------GYGGGMGGGLGGGFSA------GGGSGSGFGRGGGGGIGG 574
           +A+ GG+ G            Y  G G GL GGFS+      GG     F    G G  G
Sbjct: 11  AAAKGGFSGCSAVLSGGSSSSYRAG-GKGLSGGFSSRSLYSLGGARSISFNVASGSGWAG 69

Query: 575 GFG---GGSSGFSGGSGFGSIS 593
           G+G   G +SGF+ GS FGS++
Sbjct: 70  GYGFGRGRASGFA-GSMFGSVA 90



 Score = 36.6 bits (83), Expect = 0.072
 Identities = 29/84 (34%), Positives = 35/84 (41%), Gaps = 25/84 (29%)

Query: 547 GGGLGGGFSA-----GGGSGSGFGRGGGGGIGGGFGGGS-----------------SGFS 584
           G    GGFS       GGS S + R GG G+ GGF   S                 SG++
Sbjct: 10  GAAAKGGFSGCSAVLSGGSSSSY-RAGGKGLSGGFSSRSLYSLGGARSISFNVASGSGWA 68

Query: 585 GGSGFGSISGARYGVSGGGFSSAS 608
           GG GFG   G   G +G  F S +
Sbjct: 69  GGYGFG--RGRASGFAGSMFGSVA 90



 Score = 31.2 bits (69), Expect = 3.0
 Identities = 26/58 (44%), Positives = 33/58 (56%), Gaps = 6/58 (10%)

Query: 569 GGGIGGGFGGGSSGFSGGSGFGSISGARYGVSGGGFSSAS--NRGG--SIKFSQSSQS 622
           G    GGF G S+  SGGS     +G + G+S GGFSS S  + GG  SI F+ +S S
Sbjct: 10  GAAAKGGFSGCSAVLSGGSSSSYRAGGK-GLS-GGFSSRSLYSLGGARSISFNVASGS 65


>gi|15618995 keratin 71 [Homo sapiens]
          Length = 523

 Score =  551 bits (1420), Expect = e-157
 Identities = 323/587 (55%), Positives = 394/587 (67%), Gaps = 80/587 (13%)

Query: 1   MSRQASKTSGGGSQG-FSGRSAVVSGSSRMSCVAHSGGAGGGAYGFRSGAGGFGSRSLYN 59
           MSRQ +  SG  ++G FSG SAV+SG S  S  A S G           +GGFGSRSLY+
Sbjct: 1   MSRQFTCKSGAAAKGGFSGCSAVLSGGSSSSFRAGSKGL----------SGGFGSRSLYS 50

Query: 60  LGGNKSISISVAAGGSRAGGFGGGRSSCAFAGGYGGGFGSGYGGGFGGGFGGGRGMGGGF 119
           LGG +  S++VA+G  ++GG+               GFG G   GF G   G   +G   
Sbjct: 51  LGGVR--SLNVASGSGKSGGY---------------GFGRGRASGFAGSMFGSVALGP-- 91

Query: 120 GGAGGFGGAGGFGGAGGFGGPGGFGGSGGFGGPGSLGSPGGFGPGGFPGGIQEVTINQSL 179
                                                 P    PGG    I +VT+N+SL
Sbjct: 92  ------------------------------------VCPTVCPPGG----IHQVTVNESL 111

Query: 180 LQPLNVEIDPQIGQVKAQEREQIKTLNNKFASFIDKVRFLEQQNKVLETKWNLLQQQGTS 239
           L PLNVE+DP+I +V+AQEREQIK LNNKFASFIDKVRFLEQQN+VLETKW LLQQ   +
Sbjct: 112 LAPLNVELDPEIQKVRAQEREQIKALNNKFASFIDKVRFLEQQNQVLETKWELLQQLDLN 171

Query: 240 SISGTNNLEPLFENHINYLRSYLDNILGERGRLDSELKNMEDLVEDFKKKYEDEINKRTA 299
           +    NNLEP+ E +I+ LR  L+ + G+R RLDSEL+N+ D+VED+KK+YE+EINKRTA
Sbjct: 172 NCK--NNLEPILEGYISNLRKQLETLSGDRVRLDSELRNVRDVVEDYKKRYEEEINKRTA 229

Query: 300 AENEFVTLKKDVDSAYMNKVELQAKVDALIDEIDFLRTLYDAELSQMQSHISDTSVVLSM 359
           AENEFV LKKDVD+AY NKVELQAKV+++  EI F R L++AE++Q+QSHISD SV+LSM
Sbjct: 230 AENEFVLLKKDVDAAYANKVELQAKVESMDQEIKFFRCLFEAEITQIQSHISDMSVILSM 289

Query: 360 DNNRSLDLDSIIAEVRAQYEDIAQRSKAEAEALYQTKLGELQTTAGRHGDDLRNTKSEII 419
           DNNR+LDLDSII EVR QYE+IA +SKAEAEALYQTK  ELQ  AGRHGDDL+NTK+EI 
Sbjct: 290 DNNRNLDLDSIIDEVRTQYEEIALKSKAEAEALYQTKFQELQLAAGRHGDDLKNTKNEIS 349

Query: 420 ELNRMIQRLRAEIEGVKKQNANLQTAIAEAEQHGEMALKDANAKLQELQAALQQAKDDLA 479
           EL R+IQR+R+EIE VKKQ +NL+TAIA+AEQ G+ ALKDA AKL EL+ AL QAK++LA
Sbjct: 350 ELTRLIQRIRSEIENVKKQASNLETAIADAEQRGDNALKDARAKLDELEGALHQAKEELA 409

Query: 480 RLLRDYQELMNVKLALDVEIATYRKLLEGEEYRMSGECPSAVSISVVSSSTTSASAGGY- 538
           R+LR+YQELM++KLALD+EIATYRKLLE EE RMSGE PS VSIS++ SST+  S  G+ 
Sbjct: 410 RMLREYQELMSLKLALDMEIATYRKLLESEECRMSGEFPSPVSISII-SSTSGGSVYGFR 468

Query: 539 ----GGGYGGGMGGGLGGGFSAGGGSGSGFGRGGGGGIGGGFGGGSS 581
                GGY       + G  S  GG G    RG         G GSS
Sbjct: 469 PSMVSGGYVANSSNCISGVCSVRGGEGR--SRGSANDYKDTLGKGSS 513



 Score = 39.3 bits (90), Expect = 0.011
 Identities = 29/67 (43%), Positives = 37/67 (55%), Gaps = 6/67 (8%)

Query: 527 SSSTTSASAGGYGGGYGGGMGGGLGGGFSAGGGSGSGFGRGGGGGIGGGFGGGSSGFSGG 586
           SSS+  A + G  GG+G      LGG  S    SGS  G+ GG G G    G +SGF+ G
Sbjct: 28  SSSSFRAGSKGLSGGFGSRSLYSLGGVRSLNVASGS--GKSGGYGFG---RGRASGFA-G 81

Query: 587 SGFGSIS 593
           S FGS++
Sbjct: 82  SMFGSVA 88



 Score = 38.1 bits (87), Expect = 0.025
 Identities = 31/82 (37%), Positives = 34/82 (41%), Gaps = 23/82 (28%)

Query: 547 GGGLGGGFSA-----GGGSGSGFGRGGGGGIGGGFGGGS---------------SGFSGG 586
           G    GGFS       GGS S F R G  G+ GGFG  S               SG SGG
Sbjct: 10  GAAAKGGFSGCSAVLSGGSSSSF-RAGSKGLSGGFGSRSLYSLGGVRSLNVASGSGKSGG 68

Query: 587 SGFGSISGARYGVSGGGFSSAS 608
            GFG   G   G +G  F S +
Sbjct: 69  YGFG--RGRASGFAGSMFGSVA 88



 Score = 29.6 bits (65), Expect = 8.8
 Identities = 21/57 (36%), Positives = 30/57 (52%), Gaps = 2/57 (3%)

Query: 569 GGGIGGGFGGGSSGFSGGSGFGSISGARYGVSGG-GFSSASNRGGSIKFSQSSQSSQ 624
           G    GGF G S+  SGGS     +G++ G+SGG G  S  + GG    + +S S +
Sbjct: 10  GAAAKGGFSGCSAVLSGGSSSSFRAGSK-GLSGGFGSRSLYSLGGVRSLNVASGSGK 65


>gi|148612803 keratin 6 irs4 [Homo sapiens]
          Length = 529

 Score =  550 bits (1416), Expect = e-156
 Identities = 319/569 (56%), Positives = 387/569 (68%), Gaps = 62/569 (10%)

Query: 1   MSRQASKTSGGGSQGFSGRSAVVSGSSRMSCVAH-SGGAGGGAYGFRSGAGGFGSRSLYN 59
           MSRQ +  S G    FS  SAVV   +  S  ++ + G G GA        GFGSRSLY+
Sbjct: 1   MSRQLNIKSSGDKGNFSVHSAVVPRKAVGSLASYCAAGRGAGA--------GFGSRSLYS 52

Query: 60  LGGNKSISISVAAGGSRAGGFGGGRSSCAFAGGYGGGFGSGYGGGFGGGFGGGRGMGGGF 119
           LGGN+ IS +VA GG R             AGGYG   GSGYGGG   GF          
Sbjct: 53  LGGNRRISFNVAGGGVR-------------AGGYGFRPGSGYGGGRASGF---------- 89

Query: 120 GGAGGFGGAGGFGGAGGFGGPGGFGGSGGFGGPGSLGSPGGFGPGGFPGGIQEVTINQSL 179
             AG   G+   G A     P                          PGGI +VT+N+SL
Sbjct: 90  --AGSMFGSVALGPACLSVCP--------------------------PGGIHQVTVNKSL 121

Query: 180 LQPLNVEIDPQIGQVKAQEREQIKTLNNKFASFIDKVRFLEQQNKVLETKWNLLQQQGTS 239
           L PLNVE+DP+I +V+AQEREQIK LN+KFASFIDKVRFLEQQN+VLETKW LLQQ   +
Sbjct: 122 LAPLNVELDPEIQKVRAQEREQIKVLNDKFASFIDKVRFLEQQNQVLETKWELLQQLDLN 181

Query: 240 SISGTNNLEPLFENHINYLRSYLDNILGERGRLDSELKNMEDLVEDFKKKYEDEINKRTA 299
           +     NLEP+ E +I+ LR  L+ + G+R RLDSEL++M DLVED+KK+YE EIN+RT 
Sbjct: 182 NCK--KNLEPILEGYISNLRKQLETLSGDRVRLDSELRSMRDLVEDYKKRYEVEINRRTT 239

Query: 300 AENEFVTLKKDVDSAYMNKVELQAKVDALIDEIDFLRTLYDAELSQMQSHISDTSVVLSM 359
           AENEFV LKKD D+AY  KVELQAKVD+L  EI FL+ LYDAE++Q+Q+H S+TSV+LSM
Sbjct: 240 AENEFVVLKKDADAAYAVKVELQAKVDSLDKEIKFLKCLYDAEIAQIQTHASETSVILSM 299

Query: 360 DNNRSLDLDSIIAEVRAQYEDIAQRSKAEAEALYQTKLGELQTTAGRHGDDLRNTKSEII 419
           DNNR LDLDSIIAEVR  YE+IA +SKAEAEALYQTK+ ELQ  A RHGDDL++T+SE++
Sbjct: 300 DNNRDLDLDSIIAEVRMHYEEIALKSKAEAEALYQTKIQELQLAASRHGDDLKHTRSEMV 359

Query: 420 ELNRMIQRLRAEIEGVKKQNANLQTAIAEAEQHGEMALKDANAKLQELQAALQQAKDDLA 479
           ELNR+IQR+R EI  VKKQ A+L+TAIA+AEQ G+ ALKDA AKL EL+ AL QAK++LA
Sbjct: 360 ELNRLIQRIRCEIGNVKKQRASLETAIADAEQRGDNALKDAQAKLDELEGALHQAKEELA 419

Query: 480 RLLRDYQELMNVKLALDVEIATYRKLLEGEEYRMSGECPSAVSISVVSSSTTSASAGGYG 539
           R+LR+YQELM++KLALD+EIATYRKLLEGEE RMSGE PS+VSISV+SSS+ S       
Sbjct: 420 RMLREYQELMSLKLALDMEIATYRKLLEGEECRMSGENPSSVSISVISSSSYSYHHPSSA 479

Query: 540 GGYGGGMGGGLGGGFSAGGGSGSGFGRGG 568
           G   G        G +  G + +   RGG
Sbjct: 480 GVDLGASAVAGSSGSTQSGQTKTTEARGG 508



 Score = 40.4 bits (93), Expect = 0.005
 Identities = 29/89 (32%), Positives = 37/89 (41%), Gaps = 7/89 (7%)

Query: 520 AVSISVVSSSTTSASAGGYGGGYGGGMGGGLGGGFSAGGGSGSGFGRGGGGGIGGGFGGG 579
           +V  +VV      + A     G G G G G    +S GG     F   GGG   GG+   
Sbjct: 17  SVHSAVVPRKAVGSLASYCAAGRGAGAGFGSRSLYSLGGNRRISFNVAGGGVRAGGY--- 73

Query: 580 SSGFSGGSGFGSISGARYGVSGGGFSSAS 608
             GF  GSG+G   G   G +G  F S +
Sbjct: 74  --GFRPGSGYG--GGRASGFAGSMFGSVA 98


>gi|28372503 keratin 72 isoform 1 [Homo sapiens]
          Length = 511

 Score =  528 bits (1359), Expect = e-150
 Identities = 305/543 (56%), Positives = 370/543 (68%), Gaps = 75/543 (13%)

Query: 1   MSRQASKTSGGGSQGFSGRSAVVSGSSRMSCVAHSGGAGGGAYGFRSGAGGFGSRSLYNL 60
           MSRQ +    G   GFSG SAV+SG           G G  +  FR+   G  S      
Sbjct: 1   MSRQLTHFPRGERLGFSGCSAVLSG-----------GIGSSSASFRARVKGSASF----- 44

Query: 61  GGNKSISISVAAGGSRAGGFGGGRSSCAFAGGYGGGFGSGYGGGFGGGFGGGRGMGGGFG 120
            G+KS+S             GG RS    A    GG                        
Sbjct: 45  -GSKSLSC-----------LGGSRSLALSAAARRGG------------------------ 68

Query: 121 GAGGFGGAGGFGGAGGFGGPGGFGGSGGFGGPGSLGSPGGFGPGGFPGGIQEVTINQSLL 180
                G  GGF G           GS G G       P        PGGI +VT+N+SLL
Sbjct: 69  -----GRLGGFVGTAF--------GSAGLGPKCPSVCP--------PGGIPQVTVNKSLL 107

Query: 181 QPLNVEIDPQIGQVKAQEREQIKTLNNKFASFIDKVRFLEQQNKVLETKWNLLQQQGTSS 240
            PLNVE+DP+I +V+AQEREQIK LNNKFASFIDKVRFLEQQN+VLETKWNLLQQ   ++
Sbjct: 108 APLNVEMDPEIQRVRAQEREQIKALNNKFASFIDKVRFLEQQNQVLETKWNLLQQLDLNN 167

Query: 241 ISGTNNLEPLFENHINYLRSYLDNILGERGRLDSELKNMEDLVEDFKKKYEDEINKRTAA 300
                NLEP++E +I+ L+  L+ + G+  RLDSEL+NM+DLVED+KK+YE EIN+RTAA
Sbjct: 168 CR--KNLEPIYEGYISNLQKQLEMLSGDGVRLDSELRNMQDLVEDYKKRYEVEINRRTAA 225

Query: 301 ENEFVTLKKDVDSAYMNKVELQAKVDALIDEIDFLRTLYDAELSQMQSHISDTSVVLSMD 360
           ENEFV LKKDVD+AYMNKVELQAKVD+L DEI F + LY+ E++Q+QSHISDTS+VLSMD
Sbjct: 226 ENEFVVLKKDVDAAYMNKVELQAKVDSLTDEIKFFKCLYEGEITQIQSHISDTSIVLSMD 285

Query: 361 NNRSLDLDSIIAEVRAQYEDIAQRSKAEAEALYQTKLGELQTTAGRHGDDLRNTKSEIIE 420
           NNR LDLDSIIAEVRAQYE+IA +SKAEAE LYQTK+ ELQ TAG+HGDDL+ TK+EI E
Sbjct: 286 NNRDLDLDSIIAEVRAQYEEIALKSKAEAETLYQTKIQELQVTAGQHGDDLKLTKAEISE 345

Query: 421 LNRMIQRLRAEIEGVKKQNANLQTAIAEAEQHGEMALKDANAKLQELQAALQQAKDDLAR 480
           LNR+IQR+R+EI  VKKQ A+L+TAIA+AEQ G+ ALKDA AKL EL+ AL QAK++LAR
Sbjct: 346 LNRLIQRIRSEIGNVKKQCADLETAIADAEQRGDCALKDARAKLDELEGALHQAKEELAR 405

Query: 481 LLRDYQELMNVKLALDVEIATYRKLLEGEEYRMSGECPSAVSISVVSSSTTSASAGGYGG 540
           +LR+YQEL+++KLALD+EIATYRKLLE EE RMSGE P++VSISV+SS+   A   G+  
Sbjct: 406 MLREYQELVSLKLALDMEIATYRKLLESEECRMSGEYPNSVSISVISSTNAGAGGAGFSM 465

Query: 541 GYG 543
           G+G
Sbjct: 466 GFG 468


>gi|226246663 keratin 72 isoform 1 [Homo sapiens]
          Length = 511

 Score =  528 bits (1359), Expect = e-150
 Identities = 305/543 (56%), Positives = 370/543 (68%), Gaps = 75/543 (13%)

Query: 1   MSRQASKTSGGGSQGFSGRSAVVSGSSRMSCVAHSGGAGGGAYGFRSGAGGFGSRSLYNL 60
           MSRQ +    G   GFSG SAV+SG           G G  +  FR+   G  S      
Sbjct: 1   MSRQLTHFPRGERLGFSGCSAVLSG-----------GIGSSSASFRARVKGSASF----- 44

Query: 61  GGNKSISISVAAGGSRAGGFGGGRSSCAFAGGYGGGFGSGYGGGFGGGFGGGRGMGGGFG 120
            G+KS+S             GG RS    A    GG                        
Sbjct: 45  -GSKSLSC-----------LGGSRSLALSAAARRGG------------------------ 68

Query: 121 GAGGFGGAGGFGGAGGFGGPGGFGGSGGFGGPGSLGSPGGFGPGGFPGGIQEVTINQSLL 180
                G  GGF G           GS G G       P        PGGI +VT+N+SLL
Sbjct: 69  -----GRLGGFVGTAF--------GSAGLGPKCPSVCP--------PGGIPQVTVNKSLL 107

Query: 181 QPLNVEIDPQIGQVKAQEREQIKTLNNKFASFIDKVRFLEQQNKVLETKWNLLQQQGTSS 240
            PLNVE+DP+I +V+AQEREQIK LNNKFASFIDKVRFLEQQN+VLETKWNLLQQ   ++
Sbjct: 108 APLNVEMDPEIQRVRAQEREQIKALNNKFASFIDKVRFLEQQNQVLETKWNLLQQLDLNN 167

Query: 241 ISGTNNLEPLFENHINYLRSYLDNILGERGRLDSELKNMEDLVEDFKKKYEDEINKRTAA 300
                NLEP++E +I+ L+  L+ + G+  RLDSEL+NM+DLVED+KK+YE EIN+RTAA
Sbjct: 168 CR--KNLEPIYEGYISNLQKQLEMLSGDGVRLDSELRNMQDLVEDYKKRYEVEINRRTAA 225

Query: 301 ENEFVTLKKDVDSAYMNKVELQAKVDALIDEIDFLRTLYDAELSQMQSHISDTSVVLSMD 360
           ENEFV LKKDVD+AYMNKVELQAKVD+L DEI F + LY+ E++Q+QSHISDTS+VLSMD
Sbjct: 226 ENEFVVLKKDVDAAYMNKVELQAKVDSLTDEIKFFKCLYEGEITQIQSHISDTSIVLSMD 285

Query: 361 NNRSLDLDSIIAEVRAQYEDIAQRSKAEAEALYQTKLGELQTTAGRHGDDLRNTKSEIIE 420
           NNR LDLDSIIAEVRAQYE+IA +SKAEAE LYQTK+ ELQ TAG+HGDDL+ TK+EI E
Sbjct: 286 NNRDLDLDSIIAEVRAQYEEIALKSKAEAETLYQTKIQELQVTAGQHGDDLKLTKAEISE 345

Query: 421 LNRMIQRLRAEIEGVKKQNANLQTAIAEAEQHGEMALKDANAKLQELQAALQQAKDDLAR 480
           LNR+IQR+R+EI  VKKQ A+L+TAIA+AEQ G+ ALKDA AKL EL+ AL QAK++LAR
Sbjct: 346 LNRLIQRIRSEIGNVKKQCADLETAIADAEQRGDCALKDARAKLDELEGALHQAKEELAR 405

Query: 481 LLRDYQELMNVKLALDVEIATYRKLLEGEEYRMSGECPSAVSISVVSSSTTSASAGGYGG 540
           +LR+YQEL+++KLALD+EIATYRKLLE EE RMSGE P++VSISV+SS+   A   G+  
Sbjct: 406 MLREYQELVSLKLALDMEIATYRKLLESEECRMSGEYPNSVSISVISSTNAGAGGAGFSM 465

Query: 541 GYG 543
           G+G
Sbjct: 466 GFG 468


>gi|4504919 keratin 8 [Homo sapiens]
          Length = 483

 Score =  503 bits (1295), Expect = e-142
 Identities = 270/444 (60%), Positives = 331/444 (74%), Gaps = 16/444 (3%)

Query: 127 GAGGFGGAGGFGGPGGFGGSGGFGGPGSL----GSPGGFGPGGFPGGIQEVTINQSLLQP 182
           G   F       GPG    S  F   GS     G  GG+G     GGI  VT+NQSLL P
Sbjct: 16  GPRAFSSRSYTSGPGSRISSSSFSRVGSSNFRGGLGGGYGGASGMGGITAVTVNQSLLSP 75

Query: 183 LNVEIDPQIGQVKAQEREQIKTLNNKFASFIDKVRFLEQQNKVLETKWNLLQQQGTSSIS 242
           L +E+DP I  V+ QE+EQIKTLNNKFASFIDKVRFLEQQNK+LETKW+LLQQQ T+   
Sbjct: 76  LVLEVDPNIQAVRTQEKEQIKTLNNKFASFIDKVRFLEQQNKMLETKWSLLQQQKTAR-- 133

Query: 243 GTNNLEPLFENHINYLRSYLDNILGERGRLDSELKNMEDLVEDFKKKYEDEINKRTAAEN 302
             +N++ +FE++IN LR  L+ +  E+ +L++EL NM+ LVEDFK KYEDEINKRT  EN
Sbjct: 134 --SNMDNMFESYINNLRRQLETLGQEKLKLEAELGNMQGLVEDFKNKYEDEINKRTEMEN 191

Query: 303 EFVTLKKDVDSAYMNKVELQAKVDALIDEIDFLRTLYDAELSQMQSHISDTSVVLSMDNN 362
           EFV +KKDVD AYMNKVEL+++++ L DEI+FLR LY+ E+ ++QS ISDTSVVLSMDN+
Sbjct: 192 EFVLIKKDVDEAYMNKVELESRLEGLTDEINFLRQLYEEEIRELQSQISDTSVVLSMDNS 251

Query: 363 RSLDLDSIIAEVRAQYEDIAQRSKAEAEALYQTKLGELQTTAGRHGDDLRNTKSEIIELN 422
           RSLD+DSIIAEV+AQYEDIA RS+AEAE++YQ K  ELQ+ AG+HGDDLR TK+EI E+N
Sbjct: 252 RSLDMDSIIAEVKAQYEDIANRSRAEAESMYQIKYEELQSLAGKHGDDLRRTKTEISEMN 311

Query: 423 RMIQRLRAEIEGVKKQNANLQTAIAEAEQHGEMALKDANAKLQELQAALQQAKDDLARLL 482
           R I RL+AEIEG+K Q A+L+ AIA+AEQ GE+A+KDANAKL EL+AALQ+AK D+AR L
Sbjct: 312 RNISRLQAEIEGLKGQRASLEAAIADAEQRGELAIKDANAKLSELEAALQRAKQDMARQL 371

Query: 483 RDYQELMNVKLALDVEIATYRKLLEGEEYRMSGECPSAVSISVVSSSTTSASAGGYGGGY 542
           R+YQELMNVKLALD+EIATYRKLLEGEE R+     S +    + + TTS  AGG    Y
Sbjct: 372 REYQELMNVKLALDIEIATYRKLLEGEESRLE----SGMQNMSIHTKTTSGYAGGLSSAY 427

Query: 543 GG----GMGGGLGGGFSAGGGSGS 562
           GG    G+   LG  F +G GS S
Sbjct: 428 GGLTSPGLSYSLGSSFGSGAGSSS 451



 Score = 32.3 bits (72), Expect = 1.4
 Identities = 22/59 (37%), Positives = 30/59 (50%), Gaps = 9/59 (15%)

Query: 1  MSRQASKTSGGGSQGFSGRSAVVSGSSRMSCVAHS--------GGAGGGAYGFRSGAGG 51
          +++++ K S  G + FS RS      SR+S  + S        GG GGG YG  SG GG
Sbjct: 5  VTQKSYKVSTSGPRAFSSRSYTSGPGSRISSSSFSRVGSSNFRGGLGGG-YGGASGMGG 62



 Score = 31.2 bits (69), Expect = 3.0
 Identities = 16/43 (37%), Positives = 22/43 (51%), Gaps = 3/43 (6%)

Query: 554 FSAGGGS---GSGFGRGGGGGIGGGFGGGSSGFSGGSGFGSIS 593
           +++G GS    S F R G     GG GGG  G SG  G  +++
Sbjct: 25  YTSGPGSRISSSSFSRVGSSNFRGGLGGGYGGASGMGGITAVT 67



 Score = 30.0 bits (66), Expect = 6.7
 Identities = 19/65 (29%), Positives = 29/65 (44%), Gaps = 1/65 (1%)

Query: 493 LALDVEIATYRKLLEGEEYRMSGECPSAVSISVVSSSTTSASAGGYGGGYGGGMGGGLG- 551
           +++ V   +Y+    G     S    S     + SSS +   +  + GG GGG GG  G 
Sbjct: 1   MSIRVTQKSYKVSTSGPRAFSSRSYTSGPGSRISSSSFSRVGSSNFRGGLGGGYGGASGM 60

Query: 552 GGFSA 556
           GG +A
Sbjct: 61  GGITA 65


>gi|67782365 keratin 7 [Homo sapiens]
          Length = 469

 Score =  488 bits (1256), Expect = e-138
 Identities = 265/425 (62%), Positives = 329/425 (77%), Gaps = 8/425 (1%)

Query: 140 PGGFGGSGGFGGPGS---LGSPGGFGPGGFPGGIQEVTINQSLLQPLNVEIDPQIGQVKA 196
           PGG G S  +G   S   +     +G G    GI+EVTINQSLL PL ++ DP + +V+ 
Sbjct: 31  PGGLGSSSLYGLGASRPRVAVRSAYG-GPVGAGIREVTINQSLLAPLRLDADPSLQRVRQ 89

Query: 197 QEREQIKTLNNKFASFIDKVRFLEQQNKVLETKWNLLQQQGTSSISGTNNLEPLFENHIN 256
           +E EQIKTLNNKFASFIDKVRFLEQQNK+LETKW LLQ+Q ++  S    L  +FE  I 
Sbjct: 90  EESEQIKTLNNKFASFIDKVRFLEQQNKLLETKWTLLQEQKSAKSS---RLPDIFEAQIA 146

Query: 257 YLRSYLDNILGERGRLDSELKNMEDLVEDFKKKYEDEINKRTAAENEFVTLKKDVDSAYM 316
            LR  L+ +  + GRL++EL++M+D+VEDFK KYEDEIN RTAAENEFV LKKDVD+AYM
Sbjct: 147 GLRGQLEALQVDGGRLEAELRSMQDVVEDFKNKYEDEINHRTAAENEFVVLKKDVDAAYM 206

Query: 317 NKVELQAKVDALIDEIDFLRTLYDAELSQMQSHISDTSVVLSMDNNRSLDLDSIIAEVRA 376
           +KVEL+AKVDAL DEI+FLRTL + EL+++QS ISDTSVVLSMDN+RSLDLD IIAEV+A
Sbjct: 207 SKVELEAKVDALNDEINFLRTLNETELTELQSQISDTSVVLSMDNSRSLDLDGIIAEVKA 266

Query: 377 QYEDIAQRSKAEAEALYQTKLGELQTTAGRHGDDLRNTKSEIIELNRMIQRLRAEIEGVK 436
           QYE++A+ S+AEAEA YQTK   LQ  AG+HGDDLRNT++EI E+NR IQRL+AEI+ +K
Sbjct: 267 QYEEMAKCSRAEAEAWYQTKFETLQAQAGKHGDDLRNTRNEISEMNRAIQRLQAEIDNIK 326

Query: 437 KQNANLQTAIAEAEQHGEMALKDANAKLQELQAALQQAKDDLARLLRDYQELMNVKLALD 496
            Q A L+ AIAEAE+ GE+ALKDA AK +EL+AALQ+ K D+AR LR+YQELM+VKLALD
Sbjct: 327 NQRAKLEAAIAEAEERGELALKDARAKQEELEAALQRGKQDMARQLREYQELMSVKLALD 386

Query: 497 VEIATYRKLLEGEEYRMSGECPSAVSISVVSSSTTSASAGGYGGGYGGGMGGGLGGGFSA 556
           +EIATYRKLLEGEE R++G+   AV+ISV++S+  S+S GG G   GG MG      FS+
Sbjct: 387 IEIATYRKLLEGEESRLAGDGVGAVNISVMNSTGGSSSGGGIGLTLGGTMGSN-ALSFSS 445

Query: 557 GGGSG 561
             G G
Sbjct: 446 SAGPG 450


>gi|15431316 keratin, hair, basic, 4 [Homo sapiens]
          Length = 600

 Score =  468 bits (1205), Expect = e-132
 Identities = 297/622 (47%), Positives = 375/622 (60%), Gaps = 64/622 (10%)

Query: 1   MSRQASKTSGGGSQGFSGRSAVVSGSSRMSCVAHSGGAGGGAYGFRSGAGGFGSRSLYNL 60
           MS ++ + S G   G     + ++  +     A+S     G  GFR G G FGSRS+   
Sbjct: 1   MSCRSYRVSSGHRVGNFSSCSAMTPQNLNRFRANSVSCWSGP-GFR-GLGSFGSRSVITF 58

Query: 61  GGNKSISISVAAGGSRAGGFGGGRSSCAFAGGYGGGFGSGYGGGFGGGFGGGRGMGGGFG 120
           G   S S  +AA GSR          C          G  +G G G GFG GRG+G G  
Sbjct: 59  G---SYSPRIAAVGSRP-------IHC----------GVRFGAGCGMGFGDGRGVGLGPR 98

Query: 121 GAGGFGGAGGFGGAGGFGGPGGFGGSGGFGGPGSLGSPGGFGPGGFPGGIQEVTINQSLL 180
                G   GFG   G G         GFGGPG     GG G    P  I  VT+N+SLL
Sbjct: 99  ADSCVGL--GFGAGSGIGY--------GFGGPGFGYRVGGVGVPAAPS-ITAVTVNKSLL 147

Query: 181 QPLNVEIDPQIGQVKAQEREQIKTLNNKFASFIDKVRFLEQQNKVLETKWNLLQQQGTSS 240
            PLN+EIDP   +VK  E+EQIKTLNNKFASFIDKVRFLEQQNK+LETKW+ LQ+Q    
Sbjct: 148 TPLNLEIDPNAQRVKKDEKEQIKTLNNKFASFIDKVRFLEQQNKLLETKWSFLQEQKCIR 207

Query: 241 ISGTNNLEPLFENHINYLRSYLDNILGERGRLDSELKNMEDLVEDFKKKYEDEINKRTAA 300
               +NLEPLFE++I  LR  L+ ++ ++ RL +E  +++D++E FKKKYE+E+  R  A
Sbjct: 208 ----SNLEPLFESYITNLRRQLEVLVSDQARLQAERNHLQDVLEGFKKKYEEEVVCRANA 263

Query: 301 ENEFVTLKKDVDSAYMNKVELQAKVDALIDEIDFLRTLYDAELSQMQSHISDTSVVLSMD 360
           ENEFV LKKDVD+A+MNK +L+A VD L  EIDFL+TLY  E+  +QSHIS+TSV++ MD
Sbjct: 264 ENEFVALKKDVDAAFMNKSDLEANVDTLTQEIDFLKTLYMEEIQLLQSHISETSVIVKMD 323

Query: 361 NNRSLDLDSIIAEVRAQYEDIAQRSKAEAEALYQTKLGELQTTAGRHGDDLRNTKSEIIE 420
           N+R L+LD IIAEV+AQYE++A+RS+A+AEA YQTK  E+Q TAG+H D+LRN ++EI E
Sbjct: 324 NSRDLNLDGIIAEVKAQYEEVARRSRADAEAWYQTKYEEMQVTAGQHCDNLRNIRNEINE 383

Query: 421 LNRMIQRLRAEIEGVKKQNANLQTAIAEAEQHGEMALKDANAKLQELQAALQQAKDDLAR 480
           L R+IQRL+AEIE  K Q A L+ A+AEAEQ GE  L DA  KL +L+ ALQQAK D+AR
Sbjct: 384 LTRLIQRLKAEIEHAKAQRAKLEAAVAEAEQQGEATLSDAKCKLADLECALQQAKQDMAR 443

Query: 481 LLRDYQELMNVKLALDVEIATYRKLLEGEEYRMSGECPSAVSISVVSSSTTSASAGGYGG 540
            L +YQELMN KL LD+EIATYR+LLEGEE R+  E    V+ISV SS            
Sbjct: 444 QLCEYQELMNAKLGLDIEIATYRRLLEGEESRLC-EGVGPVNISVSSSR----------- 491

Query: 541 GYGGGMGGGLGGGFSAGGG---SGSGFGRGGGGGIGGGFGGGSSGFSGGSGFGSISGARY 597
                      GG   G     +GS   RGG    G      +SG     G  S+ GAR 
Sbjct: 492 -----------GGLVCGPEPLVAGSTLSRGGVTFSGSSSVCATSGVLASCG-PSLGGARV 539

Query: 598 GVSGGGFSSASNRGGSIKFSQS 619
             + G   S   R GS+  S++
Sbjct: 540 APATGDLLSTGTRSGSMLISEA 561


>gi|89357932 keratin 5b [Homo sapiens]
          Length = 520

 Score =  460 bits (1183), Expect = e-129
 Identities = 260/470 (55%), Positives = 323/470 (68%), Gaps = 28/470 (5%)

Query: 117 GGFGGAGGFGGAG--GFGGA--GGFGGPGGFGGSGGF------GGPGSLGSPGGFGPGGF 166
           GGF   GGF       FGG   G  G   G GG  G       GGPG    P        
Sbjct: 28  GGFSSRGGFSSRSLNSFGGCLEGSRGSTWGSGGRLGVRFGEWSGGPGLSLCP-------- 79

Query: 167 PGGIQEVTINQSLLQPLNVEIDPQIGQVKAQEREQIKTLNNKFASFIDKVRFLEQQNKVL 226
           PGGIQEVTINQ+LL PL +EIDPQ   V+ QE ++I+TLNN+FASFIDKVRFLEQQNKVL
Sbjct: 80  PGGIQEVTINQNLLTPLKIEIDPQFQVVRTQETQEIRTLNNQFASFIDKVRFLEQQNKVL 139

Query: 227 ETKWNLLQQQGTSSISGTNNLEPLFENHINYLRSYLDNILGERGRLDSELKNMEDLVEDF 286
           ETKW+LLQQQG S       LEP+FE  ++ LR  L+ + GERG LD+ELK   D  E++
Sbjct: 140 ETKWHLLQQQGLSG--SQQGLEPVFEACLDQLRKQLEQLQGERGALDAELKACRDQEEEY 197

Query: 287 KKKYEDEINKRTAAENEFVTLKKDVDSAYMNKVELQAKVDALIDEIDFLRTLYDAELSQM 346
           K KYE+E ++R   EN+FV LKKDVD  +++K+EL+ K++AL + + FL+ L + EL Q+
Sbjct: 198 KSKYEEEAHRRATLENDFVVLKKDVDGVFLSKMELEGKLEALREYLYFLKHLNEEELGQL 257

Query: 347 QSHISDTSVVLSMDNNRSLDLDSIIAEVRAQYEDIAQRSKAEAEALYQTKLGELQTTAGR 406
           Q+  SDTSVVLSMDNNR LD  SII EVRA+YE+IA+ SKAEAEALYQTK  ELQ +A  
Sbjct: 258 QTQASDTSVVLSMDNNRYLDFSSIITEVRARYEEIARSSKAEAEALYQTKYQELQVSAQL 317

Query: 407 HGDDLRNTKSEIIELNRMIQRLRAEIEGVKKQNANLQTAIAEAEQHGEMALKDANAKLQE 466
           HGD ++ TK +I +L++ IQRL+++ E +KKQNA+LQ AI +AEQ GE+ALKDA AK+ E
Sbjct: 318 HGDRMQETKVQISQLHQEIQRLQSQTENLKKQNASLQAAITDAEQRGELALKDAQAKVDE 377

Query: 467 LQAALQQAKDDLARLLRDYQELMNVKLALDVEIATYRKLLEGEEYRMSGECPSAVSISVV 526
           L+AAL+ AK +LARLL +YQEL + KL+LDVEIATYR+LLEGEE RMSGEC S V+IS V
Sbjct: 378 LEAALRMAKQNLARLLCEYQELTSTKLSLDVEIATYRRLLEGEECRMSGECTSQVTISSV 437

Query: 527 SSSTTSASAGGYGGGYGGGMGG--GLGGGFSAGGGSGSGFGRGGGGGIGG 574
             S   +      GG GGG+G   GLG G  + G   +    GG   I G
Sbjct: 438 GGSAVMS------GGVGGGLGSTCGLGSGKGSPGSCCTSIVTGGSNIILG 481


>gi|4504935 keratin 85 [Homo sapiens]
          Length = 507

 Score =  418 bits (1075), Expect = e-117
 Identities = 235/449 (52%), Positives = 304/449 (67%), Gaps = 17/449 (3%)

Query: 119 FGGAGGFGGAGGFGGAG--GFGGPGGFGGSGGFGGPGSLGSPGGFGPGGF----PGGIQE 172
           + G   + G  GFG       G  G     GGF   GS G   G+  GG     P  I  
Sbjct: 39  YRGVSCYRGLTGFGSRSLCNLGSCGPRIAVGGFRA-GSCGRSFGYRSGGVCGPSPPCITT 97

Query: 173 VTINQSLLQPLNVEIDPQIGQVKAQEREQIKTLNNKFASFIDKVRFLEQQNKVLETKWNL 232
           V++N+SLL PLN+EIDP    VK +E+EQIK+LN++FA+FIDKVRFLEQQNK+LETKW  
Sbjct: 98  VSVNESLLTPLNLEIDPNAQCVKQEEKEQIKSLNSRFAAFIDKVRFLEQQNKLLETKWQF 157

Query: 233 LQQQGTSSISGTNNLEPLFENHINYLRSYLDNILGERGRLDSELKNMEDLVEDFKKKYED 292
            Q Q        +NLEPLF  +I  LR   + +  + GRL SEL ++++++E +KKKYE+
Sbjct: 158 YQNQRCCE----SNLEPLFSGYIETLRREAECVEADSGRLASELNHVQEVLEGYKKKYEE 213

Query: 293 EINKRTAAENEFVTLKKDVDSAYMNKVELQAKVDALIDEIDFLRTLYDAELSQMQSHISD 352
           E+  R  AENEFV LKKDVD AY+ K +L+A V+AL++E  FLR LY+ E+  +Q+HISD
Sbjct: 214 EVALRATAENEFVVLKKDVDCAYLRKSDLEANVEALVEESSFLRRLYEEEIRVLQAHISD 273

Query: 353 TSVVLSMDNNRSLDLDSIIAEVRAQYEDIAQRSKAEAEALYQTKLGELQTTAGRHGDDLR 412
           TSV++ MDN+R L++D IIAE++AQY+D+A RS+AEAE+ Y++K  E++ T  RHG+ LR
Sbjct: 274 TSVIVKMDNSRDLNMDCIIAEIKAQYDDVASRSRAEAESWYRSKCEEMKATVIRHGETLR 333

Query: 413 NTKSEIIELNRMIQRLRAEIEGVKKQNANLQTAIAEAEQHGEMALKDANAKLQELQAALQ 472
            TK EI ELNRMIQRL AEIE  K Q A L+ A+AEAEQ GE AL DA  KL EL+ ALQ
Sbjct: 334 RTKEEINELNRMIQRLTAEIENAKCQRAKLEAAVAEAEQQGEAALSDARCKLAELEGALQ 393

Query: 473 QAKDDLARLLRDYQELMNVKLALDVEIATYRKLLEGEEYRMSGECPSAVSISV-VSSSTT 531
           +AK D+A LL++YQE+MN KL LD+EIATYR+LLEGEE+R+   C    S++V VSSS  
Sbjct: 394 KAKQDMACLLKEYQEVMNSKLGLDIEIATYRRLLEGEEHRL---CEGVGSVNVCVSSSRG 450

Query: 532 SASAGGYGGGYGGGMGGGLGGGFSAGGGS 560
             S GG    Y    G  +  G SA GGS
Sbjct: 451 GVSCGGL--SYSTTPGRQITSGPSAIGGS 477



 Score = 42.0 bits (97), Expect = 0.002
 Identities = 32/86 (37%), Positives = 40/86 (46%), Gaps = 13/86 (15%)

Query: 11 GGSQGFSGRSAVVSGSSRMSCVAHSGGAGGGAYGFRSGAGGFGSRSLYNLGGNKSISISV 70
          G ++ FS  SAV   +    C++ +   G   Y    G  GFGSRSL NLG   S    +
Sbjct: 13 GVTRNFSSCSAVAPKTGNRCCISAAPYRGVSCY---RGLTGFGSRSLCNLG---SCGPRI 66

Query: 71 AAGGSRAGGFGGGRSSCAFAGGYGGG 96
          A GG RAG       SC  + GY  G
Sbjct: 67 AVGGFRAG-------SCGRSFGYRSG 85


>gi|226246665 keratin 72 isoform 2 [Homo sapiens]
          Length = 469

 Score =  415 bits (1067), Expect = e-116
 Identities = 264/547 (48%), Positives = 326/547 (59%), Gaps = 125/547 (22%)

Query: 1   MSRQASKTSGGGSQGFSGRSAVVSGSSRMSCVAHSGGAGGGAYGFRSGAGGFGSRSLYNL 60
           MSRQ +    G   GFSG SAV+SG           G G  +  FR+   G  S      
Sbjct: 1   MSRQLTHFPRGERLGFSGCSAVLSG-----------GIGSSSASFRARVKGSASF----- 44

Query: 61  GGNKSISISVAAGGSRAGGFGGGRSSCAFAGGYGGGFGSGYGGGFGGGFGGGRGMGGGFG 120
            G+KS+S             GG RS    A    GG                        
Sbjct: 45  -GSKSLSC-----------LGGSRSLALSAAARRGG------------------------ 68

Query: 121 GAGGFGGAGGFGGAGGFGGPGGFGGSGGFGGPGSLGSPGGFGPGGFPGGIQEVTINQSLL 180
                G  GGF G           GS G G       P        PGGI +VT+N+SLL
Sbjct: 69  -----GRLGGFVGTAF--------GSAGLGPKCPSVCP--------PGGIPQVTVNKSLL 107

Query: 181 QPLNVEIDPQIGQVKAQEREQIKTLNNKFASFIDKVRFLEQQNKVLETKWNLLQQQGTSS 240
            PLNVE+DP+I +V+AQEREQIK LNNKFASFIDKVRFLEQQN+VLETKWNLLQQ   ++
Sbjct: 108 APLNVEMDPEIQRVRAQEREQIKALNNKFASFIDKVRFLEQQNQVLETKWNLLQQLDLNN 167

Query: 241 ISGTNNLEPLFENHINYLRSYLDNILGERGRLDSELKNMEDLVEDFKKKYEDEINKRTAA 300
                NLEP++E +I+ L+  L+ + G+  RLDSEL+NM+DLVED+KK+YE EIN+RTAA
Sbjct: 168 CR--KNLEPIYEGYISNLQKQLEMLSGDGVRLDSELRNMQDLVEDYKKRYEVEINRRTAA 225

Query: 301 ENEFVTLKKDVDSAYMNKVELQAKVDALIDEIDFLRTLYDAELSQMQSHISDTSVVLSMD 360
           ENEFV LKKDVD+AYMNKVELQAKVD+L DEI F + LY+ E++Q+QSHISDTS+VLSMD
Sbjct: 226 ENEFVVLKKDVDAAYMNKVELQAKVDSLTDEIKFFKCLYEGEITQIQSHISDTSIVLSMD 285

Query: 361 NNRSLDLDSIIAEVRAQYEDIAQRSKAEAEALYQTKLGELQTT---AGRHGD-DLRNTKS 416
           NNR LDLDSIIAEVRAQYE+IA +SKAEAE LYQTK  +L+T    A + GD  L++ ++
Sbjct: 286 NNRDLDLDSIIAEVRAQYEEIALKSKAEAETLYQTKCADLETAIADAEQRGDCALKDARA 345

Query: 417 EIIELNRMIQRLRAEIEGVKKQNANLQTAIAEAEQHGEMALKDANAKLQELQAALQQAKD 476
           ++ EL           EG   Q                                   AK+
Sbjct: 346 KLDEL-----------EGALHQ-----------------------------------AKE 359

Query: 477 DLARLLRDYQELMNVKLALDVEIATYRKLLEGEEYRMSGECPSAVSISVVSSSTTSASAG 536
           +LAR+LR+YQEL+++KLALD+EIATYRKLLE EE RMSGE P++VSISV+SS+   A   
Sbjct: 360 ELARMLREYQELVSLKLALDMEIATYRKLLESEECRMSGEYPNSVSISVISSTNAGAGGA 419

Query: 537 GYGGGYG 543
           G+  G+G
Sbjct: 420 GFSMGFG 426


>gi|27477127 keratin 82 [Homo sapiens]
          Length = 513

 Score =  410 bits (1054), Expect = e-114
 Identities = 237/471 (50%), Positives = 305/471 (64%), Gaps = 37/471 (7%)

Query: 132 GGAGGFGGPGGFGGSG----GFGGPGSLGSPGGFGPG---------GFPGGIQEVTINQS 178
           GG  G    G  G       GFG P      GG  PG         G    I  VTIN+S
Sbjct: 41  GGGRGLRALGCLGSRSLCNVGFGRPRVASRCGGTLPGFGYRLGATCGPSACITPVTINES 100

Query: 179 LLQPLNVEIDPQIGQVKAQEREQIKTLNNKFASFIDKVRFLEQQNKVLETKWNLLQQQGT 238
           LL PL +EIDP + +VK  E+EQIK LNN+FASFI+KVRFLEQ+NK+LETKWN +QQQ  
Sbjct: 101 LLVPLALEIDPTVQRVKRDEKEQIKCLNNRFASFINKVRFLEQKNKLLETKWNFMQQQRC 160

Query: 239 SSISGTNNLEPLFENHINYLRSYLDNILGERGRLDSELKNMEDLVEDFKKKYEDEINKRT 298
                  N+EP+FE +I+ LR  LD + G+R RL+SEL +++  +E +KKKYE+E++ R 
Sbjct: 161 CQ----TNIEPIFEGYISALRRQLDCVSGDRVRLESELCSLQAALEGYKKKYEEELSLRP 216

Query: 299 AAENEFVTLKKDVDSAYMNKVELQAKVDALIDEIDFLRTLYDAELSQMQSHISDTSVVLS 358
             ENEFV LKKDVD+A++ K +L+   +AL+ EIDFL++LY+ E+  +QS IS+TSV++ 
Sbjct: 217 CVENEFVALKKDVDTAFLMKADLETNAEALVQEIDFLKSLYEEEICLLQSQISETSVIVK 276

Query: 359 MDNNRSLDLDSIIAEVRAQYEDIAQRSKAEAEALYQTKLGELQTTAGRHGDDLRNTKSEI 418
           MDN+R LD+D IIAE++AQY+DIA RSKAEAEA YQ +  EL+ TAG H D+LRN K+EI
Sbjct: 277 MDNSRELDVDGIIAEIKAQYDDIASRSKAEAEAWYQCRYEELRVTAGNHCDNLRNRKNEI 336

Query: 419 IELNRMIQRLRAEIEGVKKQNANLQTAIAEAEQHGEMALKDANAKLQELQAALQQAKDDL 478
           +E+N++IQRL+ E E VK Q   L+ AIAEAEQ GE AL DA  KL  L+ ALQ+AK D+
Sbjct: 337 LEMNKLIQRLQQETENVKAQRCKLEGAIAEAEQQGEAALNDAKCKLAGLEEALQKAKQDM 396

Query: 479 ARLLRDYQELMNVKLALDVEIATYRKLLEGEEYRMSGECPSAVSISVVSSS--------- 529
           A LL++YQE+MN KL LD+EIATYR+LLEGEE+R+  E    V+ISV SS          
Sbjct: 397 ACLLKEYQEVMNSKLGLDIEIATYRRLLEGEEHRLC-EGIGPVNISVSSSKGAFLYEPCG 455

Query: 530 -TTSASAGGYGGGYGGGMGGGLG---------GGFSAGGGSGSGFGRGGGG 570
            +T   + G     GG    G G         G  S G G  S    G GG
Sbjct: 456 VSTPVLSTGVLRSNGGCSIVGTGELYVPCEPQGLLSCGSGRKSSMTLGAGG 506



 Score = 31.6 bits (70), Expect = 2.3
 Identities = 28/81 (34%), Positives = 37/81 (45%), Gaps = 7/81 (8%)

Query: 12 GSQGFSGRSAVVSGSSRMSCVAHSGGAGGGAYGFRSGAGGFGSRSLYNLGGNKSISISVA 71
          GSQ FS  SAV+        V+      GG  G R+  G  GSRSL N+G  +   ++  
Sbjct: 13 GSQSFSSYSAVMPRMVTHYAVSKGPCRPGGGRGLRA-LGCLGSRSLCNVGFGRP-RVASR 70

Query: 72 AGGSRAG-----GFGGGRSSC 87
           GG+  G     G   G S+C
Sbjct: 71 CGGTLPGFGYRLGATCGPSAC 91


>gi|169790853 keratin, hair, basic, 1 [Homo sapiens]
          Length = 505

 Score =  410 bits (1054), Expect = e-114
 Identities = 250/521 (47%), Positives = 324/521 (62%), Gaps = 37/521 (7%)

Query: 79  GFGGGRSSCAFAGGYGGGFGSGYGGGFGGGFGGGRGMGGGFGGAGGFGG--AGGFGGAGG 136
           GFGG   SC  A G   G        + G     RG+ GGFG     GG  AG  G + G
Sbjct: 6   GFGGRAFSCISACGPRPGRCCITAAPYRG-ISCYRGLTGGFGSHSVCGGFRAGSCGRSFG 64

Query: 137 FGGPGGFGGSGGFGGPGSLGSPGGFGPGGFPGGIQEVTINQSLLQPLNVEIDPQIGQVKA 196
           +        SGG  GP              P  I  V++N+SLL PLN+EIDP    VK 
Sbjct: 65  YR-------SGGVCGPS-------------PPCITTVSVNESLLTPLNLEIDPNAQCVKQ 104

Query: 197 QEREQIKTLNNKFASFIDKVRFLEQQNKVLETKWNLLQQQGTSSISGTNNLEPLFENHIN 256
           +E+EQIK+LN++FA+FIDKVRFLEQQNK+LETK    Q +        +NLEPLFE +I 
Sbjct: 105 EEKEQIKSLNSRFAAFIDKVRFLEQQNKLLETKLQFYQNRECCQ----SNLEPLFEGYIE 160

Query: 257 YLRSYLDNILGERGRLDSELKNMEDLVEDFKKKYEDEINKRTAAENEFVTLKKDVDSAYM 316
            LR   + +  + GRL SEL ++++++E +KKKYE+E++ R  AENEFV LKKDVD AY+
Sbjct: 161 TLRREAECVEADSGRLASELNHVQEVLEGYKKKYEEEVSLRATAENEFVALKKDVDCAYL 220

Query: 317 NKVELQAKVDALIDEIDFLRTLYDAELSQMQSHISDTSVVLSMDNNRSLDLDSIIAEVRA 376
            K +L+A V+ALI EIDFLR LY+ E+  +QSHISDTSVV+ +DN+R L++D IIAE++A
Sbjct: 221 RKSDLEANVEALIQEIDFLRRLYEEEILILQSHISDTSVVVKLDNSRDLNMDCIIAEIKA 280

Query: 377 QYEDIAQRSKAEAEALYQTKLGELQTTAGRHGDDLRNTKSEIIELNRMIQRLRAEIEGVK 436
           QY+DI  RS+AEAE+ Y++K  E++ T  RHG+ LR TK EI ELNRMIQRL AE+E  K
Sbjct: 281 QYDDIVTRSRAEAESWYRSKCEEMKATVIRHGETLRRTKEEINELNRMIQRLTAEVENAK 340

Query: 437 KQNANLQTAIAEAEQHGEMALKDANAKLQELQAALQQAKDDLARLLRDYQELMNVKLALD 496
            QN+ L+ A+A++EQ GE AL DA  KL EL+ ALQ+AK D+A L+R+YQE+MN KL LD
Sbjct: 341 CQNSKLEAAVAQSEQQGEAALSDARCKLAELEGALQKAKQDMACLIREYQEVMNSKLGLD 400

Query: 497 VEIATYRKLLEGEEYRMSGECPSAVSISV-VSSSTTSASAG-----GYGGGYGGGMGGGL 550
           +EIATYR+LLEGEE R+   C    +++V VSSS      G     G     G       
Sbjct: 401 IEIATYRRLLEGEEQRL---CEGIGAVNVCVSSSRGGVVCGDLCVSGSRPVTGSVCSAPC 457

Query: 551 GGGFSAGGGSGSGFGRGGGGGIGGGFGGGSSGFSGGSGFGS 591
            G  +   G  +  G+      GG  G GS G S   G GS
Sbjct: 458 NGNVAVSTGLCAPCGQLNTTCGGGSCGVGSCGIS-SLGVGS 497


>gi|239755818 PREDICTED: hypothetical protein isoform 2 [Homo
           sapiens]
          Length = 486

 Score =  408 bits (1049), Expect = e-114
 Identities = 219/399 (54%), Positives = 287/399 (71%), Gaps = 13/399 (3%)

Query: 138 GGPGGFGGSGGFGG--PGSLGSPGGFGPGGF----PGGIQEVTINQSLLQPLNVEIDPQI 191
           G  GGFG     GG   GS G   G+  GG     P  I  V++N+SLL PLN+EIDP  
Sbjct: 40  GLTGGFGSHSVCGGFRAGSCGRSFGYRSGGVCGPSPPCITTVSVNESLLTPLNLEIDPNA 99

Query: 192 GQVKAQEREQIKTLNNKFASFIDKVRFLEQQNKVLETKWNLLQQQGTSSISGTNNLEPLF 251
             VK +E+EQIK+LN++FA+FIDKVRFLEQQNK+LETK    Q +        +NLEPLF
Sbjct: 100 QCVKQEEKEQIKSLNSRFAAFIDKVRFLEQQNKLLETKLQFYQNRECCQ----SNLEPLF 155

Query: 252 ENHINYLRSYLDNILGERGRLDSELKNMEDLVEDFKKKYEDEINKRTAAENEFVTLKKDV 311
           E +I  LR   + +  + GRL SEL ++++++E +KKKYE+E++ R  AENEFV LKKDV
Sbjct: 156 EGYIETLRREAECVEADSGRLASELNHVQEVLEGYKKKYEEEVSLRATAENEFVALKKDV 215

Query: 312 DSAYMNKVELQAKVDALIDEIDFLRTLYDAELSQMQSHISDTSVVLSMDNNRSLDLDSII 371
           D AY+ K +L+A V+ALI EIDFLR LY+ E+  +QSHISDTSVV+ +DN+R L++D II
Sbjct: 216 DCAYLRKSDLEANVEALIQEIDFLRRLYEEEIRVLQSHISDTSVVVKLDNSRDLNMDCII 275

Query: 372 AEVRAQYEDIAQRSKAEAEALYQTKLGELQTTAGRHGDDLRNTKSEIIELNRMIQRLRAE 431
           AE++AQY+DI  RS+AEAE+ Y++K  E++ T  RHG+ LR TK EI ELNRMIQRL AE
Sbjct: 276 AEIKAQYDDIVTRSRAEAESWYRSKCEEMKATVIRHGETLRRTKEEINELNRMIQRLTAE 335

Query: 432 IEGVKKQNANLQTAIAEAEQHGEMALKDANAKLQELQAALQQAKDDLARLLRDYQELMNV 491
           +E  K QN+ L+ A+A++EQ GE AL DA  KL EL+ ALQ+AK D+A L+R+YQE+MN 
Sbjct: 336 VENAKCQNSKLEAAVAQSEQQGEAALSDARCKLAELEGALQKAKQDMACLIREYQEVMNS 395

Query: 492 KLALDVEIATYRKLLEGEEYRMSGECPSAVSISVVSSST 530
           KL LD+EIATYR+LLEGEE R+   C    S++V  SS+
Sbjct: 396 KLGLDIEIATYRRLLEGEEQRL---CEGVGSVNVCVSSS 431


>gi|239755816 PREDICTED: hypothetical protein isoform 1 [Homo
           sapiens]
          Length = 486

 Score =  408 bits (1049), Expect = e-114
 Identities = 219/399 (54%), Positives = 287/399 (71%), Gaps = 13/399 (3%)

Query: 138 GGPGGFGGSGGFGG--PGSLGSPGGFGPGGF----PGGIQEVTINQSLLQPLNVEIDPQI 191
           G  GGFG     GG   GS G   G+  GG     P  I  V++N+SLL PLN+EIDP  
Sbjct: 40  GLTGGFGSHSVCGGFRAGSCGRSFGYRSGGVCGPSPPCITTVSVNESLLTPLNLEIDPNA 99

Query: 192 GQVKAQEREQIKTLNNKFASFIDKVRFLEQQNKVLETKWNLLQQQGTSSISGTNNLEPLF 251
             VK +E+EQIK+LN++FA+FIDKVRFLEQQNK+LETK    Q +        +NLEPLF
Sbjct: 100 QCVKQEEKEQIKSLNSRFAAFIDKVRFLEQQNKLLETKLQFYQNRECCQ----SNLEPLF 155

Query: 252 ENHINYLRSYLDNILGERGRLDSELKNMEDLVEDFKKKYEDEINKRTAAENEFVTLKKDV 311
           E +I  LR   + +  + GRL SEL ++++++E +KKKYE+E++ R  AENEFV LKKDV
Sbjct: 156 EGYIETLRREAECVEADSGRLASELNHVQEVLEGYKKKYEEEVSLRATAENEFVALKKDV 215

Query: 312 DSAYMNKVELQAKVDALIDEIDFLRTLYDAELSQMQSHISDTSVVLSMDNNRSLDLDSII 371
           D AY+ K +L+A V+ALI EIDFLR LY+ E+  +QSHISDTSVV+ +DN+R L++D II
Sbjct: 216 DCAYLRKSDLEANVEALIQEIDFLRRLYEEEIRVLQSHISDTSVVVKLDNSRDLNMDCII 275

Query: 372 AEVRAQYEDIAQRSKAEAEALYQTKLGELQTTAGRHGDDLRNTKSEIIELNRMIQRLRAE 431
           AE++AQY+DI  RS+AEAE+ Y++K  E++ T  RHG+ LR TK EI ELNRMIQRL AE
Sbjct: 276 AEIKAQYDDIVTRSRAEAESWYRSKCEEMKATVIRHGETLRRTKEEINELNRMIQRLTAE 335

Query: 432 IEGVKKQNANLQTAIAEAEQHGEMALKDANAKLQELQAALQQAKDDLARLLRDYQELMNV 491
           +E  K QN+ L+ A+A++EQ GE AL DA  KL EL+ ALQ+AK D+A L+R+YQE+MN 
Sbjct: 336 VENAKCQNSKLEAAVAQSEQQGEAALSDARCKLAELEGALQKAKQDMACLIREYQEVMNS 395

Query: 492 KLALDVEIATYRKLLEGEEYRMSGECPSAVSISVVSSST 530
           KL LD+EIATYR+LLEGEE R+   C    S++V  SS+
Sbjct: 396 KLGLDIEIATYRRLLEGEEQRL---CEGVGSVNVCVSSS 431


>gi|239755814 PREDICTED: hypothetical protein isoform 3 [Homo
           sapiens]
          Length = 486

 Score =  408 bits (1049), Expect = e-114
 Identities = 219/399 (54%), Positives = 287/399 (71%), Gaps = 13/399 (3%)

Query: 138 GGPGGFGGSGGFGG--PGSLGSPGGFGPGGF----PGGIQEVTINQSLLQPLNVEIDPQI 191
           G  GGFG     GG   GS G   G+  GG     P  I  V++N+SLL PLN+EIDP  
Sbjct: 40  GLTGGFGSHSVCGGFRAGSCGRSFGYRSGGVCGPSPPCITTVSVNESLLTPLNLEIDPNA 99

Query: 192 GQVKAQEREQIKTLNNKFASFIDKVRFLEQQNKVLETKWNLLQQQGTSSISGTNNLEPLF 251
             VK +E+EQIK+LN++FA+FIDKVRFLEQQNK+LETK    Q +        +NLEPLF
Sbjct: 100 QCVKQEEKEQIKSLNSRFAAFIDKVRFLEQQNKLLETKLQFYQNRECCQ----SNLEPLF 155

Query: 252 ENHINYLRSYLDNILGERGRLDSELKNMEDLVEDFKKKYEDEINKRTAAENEFVTLKKDV 311
           E +I  LR   + +  + GRL SEL ++++++E +KKKYE+E++ R  AENEFV LKKDV
Sbjct: 156 EGYIETLRREAECVEADSGRLASELNHVQEVLEGYKKKYEEEVSLRATAENEFVALKKDV 215

Query: 312 DSAYMNKVELQAKVDALIDEIDFLRTLYDAELSQMQSHISDTSVVLSMDNNRSLDLDSII 371
           D AY+ K +L+A V+ALI EIDFLR LY+ E+  +QSHISDTSVV+ +DN+R L++D II
Sbjct: 216 DCAYLRKSDLEANVEALIQEIDFLRRLYEEEIRVLQSHISDTSVVVKLDNSRDLNMDCII 275

Query: 372 AEVRAQYEDIAQRSKAEAEALYQTKLGELQTTAGRHGDDLRNTKSEIIELNRMIQRLRAE 431
           AE++AQY+DI  RS+AEAE+ Y++K  E++ T  RHG+ LR TK EI ELNRMIQRL AE
Sbjct: 276 AEIKAQYDDIVTRSRAEAESWYRSKCEEMKATVIRHGETLRRTKEEINELNRMIQRLTAE 335

Query: 432 IEGVKKQNANLQTAIAEAEQHGEMALKDANAKLQELQAALQQAKDDLARLLRDYQELMNV 491
           +E  K QN+ L+ A+A++EQ GE AL DA  KL EL+ ALQ+AK D+A L+R+YQE+MN 
Sbjct: 336 VENAKCQNSKLEAAVAQSEQQGEAALSDARCKLAELEGALQKAKQDMACLIREYQEVMNS 395

Query: 492 KLALDVEIATYRKLLEGEEYRMSGECPSAVSISVVSSST 530
           KL LD+EIATYR+LLEGEE R+   C    S++V  SS+
Sbjct: 396 KLGLDIEIATYRRLLEGEEQRL---CEGVGSVNVCVSSS 431


>gi|14318422 keratin 86 [Homo sapiens]
          Length = 486

 Score =  408 bits (1049), Expect = e-114
 Identities = 219/399 (54%), Positives = 287/399 (71%), Gaps = 13/399 (3%)

Query: 138 GGPGGFGGSGGFGG--PGSLGSPGGFGPGGF----PGGIQEVTINQSLLQPLNVEIDPQI 191
           G  GGFG     GG   GS G   G+  GG     P  I  V++N+SLL PLN+EIDP  
Sbjct: 40  GLTGGFGSHSVCGGFRAGSCGRSFGYRSGGVCGPSPPCITTVSVNESLLTPLNLEIDPNA 99

Query: 192 GQVKAQEREQIKTLNNKFASFIDKVRFLEQQNKVLETKWNLLQQQGTSSISGTNNLEPLF 251
             VK +E+EQIK+LN++FA+FIDKVRFLEQQNK+LETK    Q +        +NLEPLF
Sbjct: 100 QCVKQEEKEQIKSLNSRFAAFIDKVRFLEQQNKLLETKLQFYQNRECCQ----SNLEPLF 155

Query: 252 ENHINYLRSYLDNILGERGRLDSELKNMEDLVEDFKKKYEDEINKRTAAENEFVTLKKDV 311
           E +I  LR   + +  + GRL SEL ++++++E +KKKYE+E++ R  AENEFV LKKDV
Sbjct: 156 EGYIETLRREAECVEADSGRLASELNHVQEVLEGYKKKYEEEVSLRATAENEFVALKKDV 215

Query: 312 DSAYMNKVELQAKVDALIDEIDFLRTLYDAELSQMQSHISDTSVVLSMDNNRSLDLDSII 371
           D AY+ K +L+A V+ALI EIDFLR LY+ E+  +QSHISDTSVV+ +DN+R L++D II
Sbjct: 216 DCAYLRKSDLEANVEALIQEIDFLRRLYEEEIRVLQSHISDTSVVVKLDNSRDLNMDCII 275

Query: 372 AEVRAQYEDIAQRSKAEAEALYQTKLGELQTTAGRHGDDLRNTKSEIIELNRMIQRLRAE 431
           AE++AQY+DI  RS+AEAE+ Y++K  E++ T  RHG+ LR TK EI ELNRMIQRL AE
Sbjct: 276 AEIKAQYDDIVTRSRAEAESWYRSKCEEMKATVIRHGETLRRTKEEINELNRMIQRLTAE 335

Query: 432 IEGVKKQNANLQTAIAEAEQHGEMALKDANAKLQELQAALQQAKDDLARLLRDYQELMNV 491
           +E  K QN+ L+ A+A++EQ GE AL DA  KL EL+ ALQ+AK D+A L+R+YQE+MN 
Sbjct: 336 VENAKCQNSKLEAAVAQSEQQGEAALSDARCKLAELEGALQKAKQDMACLIREYQEVMNS 395

Query: 492 KLALDVEIATYRKLLEGEEYRMSGECPSAVSISVVSSST 530
           KL LD+EIATYR+LLEGEE R+   C    S++V  SS+
Sbjct: 396 KLGLDIEIATYRRLLEGEEQRL---CEGVGSVNVCVSSS 431


>gi|169790841 keratin 83 [Homo sapiens]
          Length = 493

 Score =  405 bits (1041), Expect = e-113
 Identities = 219/397 (55%), Positives = 286/397 (72%), Gaps = 11/397 (2%)

Query: 138 GGPGGFGGSGGFGG--PGSLGSPGGFGPGGF----PGGIQEVTINQSLLQPLNVEIDPQI 191
           G  GGFG     GG   GS G   G+  GG     P  I  V++N+SLL PLN+EIDP  
Sbjct: 45  GLTGGFGSHSVCGGFRAGSCGRSFGYRSGGVCGPSPPCITTVSVNESLLTPLNLEIDPNA 104

Query: 192 GQVKAQEREQIKTLNNKFASFIDKVRFLEQQNKVLETKWNLLQQQGTSSISGTNNLEPLF 251
             VK +E+EQIK+LN++FA+FIDKVRFLEQQNK+LETK    Q +        +NLEPLF
Sbjct: 105 QCVKQEEKEQIKSLNSRFAAFIDKVRFLEQQNKLLETKLQFYQNRECCQ----SNLEPLF 160

Query: 252 ENHINYLRSYLDNILGERGRLDSELKNMEDLVEDFKKKYEDEINKRTAAENEFVTLKKDV 311
             +I  LR   + +  + GRL SEL ++++++E +KKKYE+E+  R  AENEFV LKKDV
Sbjct: 161 AGYIETLRREAECVEADSGRLASELNHVQEVLEGYKKKYEEEVALRATAENEFVALKKDV 220

Query: 312 DSAYMNKVELQAKVDALIDEIDFLRTLYDAELSQMQSHISDTSVVLSMDNNRSLDLDSII 371
           D AY+ K +L+A V+ALI EIDFLR LY+ E+  +QSHISDTSVV+ +DN+R L++D I+
Sbjct: 221 DCAYLRKSDLEANVEALIQEIDFLRRLYEEEIRILQSHISDTSVVVKLDNSRDLNMDCIV 280

Query: 372 AEVRAQYEDIAQRSKAEAEALYQTKLGELQTTAGRHGDDLRNTKSEIIELNRMIQRLRAE 431
           AE++AQY+DIA RS+AEAE+ Y++K  E++ T  RHG+ LR TK EI ELNRMIQRL AE
Sbjct: 281 AEIKAQYDDIATRSRAEAESWYRSKCEEMKATVIRHGETLRRTKEEINELNRMIQRLTAE 340

Query: 432 IEGVKKQNANLQTAIAEAEQHGEMALKDANAKLQELQAALQQAKDDLARLLRDYQELMNV 491
           +E  K QN+ L+ A+A++EQ GE AL DA  KL EL+ ALQ+AK D+A L+R+YQE+MN 
Sbjct: 341 VENAKCQNSKLEAAVAQSEQQGEAALSDARCKLAELEGALQKAKQDMACLIREYQEVMNS 400

Query: 492 KLALDVEIATYRKLLEGEEYRMSGECPSAVSISVVSS 528
           KL LD+EIATYR+LLEGEE R+  E   AV++ V SS
Sbjct: 401 KLGLDIEIATYRRLLEGEEQRLC-EGVEAVNVCVSSS 436


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.312    0.135    0.383 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 25,158,992
Number of Sequences: 37866
Number of extensions: 1696836
Number of successful extensions: 85019
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 830
Number of HSP's successfully gapped in prelim test: 726
Number of HSP's that attempted gapping in prelim test: 14292
Number of HSP's gapped (non-prelim): 24870
length of query: 628
length of database: 18,247,518
effective HSP length: 108
effective length of query: 520
effective length of database: 14,157,990
effective search space: 7362154800
effective search space used: 7362154800
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 65 (29.6 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.

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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.