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Search of human proteins with 109134340
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|109134340 tubulin tyrosine ligase-like family, member 3
[Homo sapiens]
(772 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|109134340 tubulin tyrosine ligase-like family, member 3 [Homo... 1589 0.0
gi|122937293 tubulin tyrosine ligase-like family, member 8 [Homo... 462 e-130
gi|11068135 tubulin tyrosine ligase-like family, member 1 [Homo ... 113 8e-25
gi|50658079 tubulin tyrosine ligase-like family, member 5 [Homo ... 110 5e-24
gi|99028883 tubulin tyrosine ligase-like family, member 2 [Homo ... 104 3e-22
gi|194239681 tubulin tyrosine ligase-like family, member 10 isof... 101 2e-21
gi|56606131 tubulin tyrosine ligase-like family, member 9 [Homo ... 99 1e-20
gi|24308516 tubulin tyrosine ligase [Homo sapiens] 98 3e-20
gi|217330594 tubulin tyrosine ligase-like family, member 4 [Homo... 96 1e-19
gi|94536793 tubulin tyrosine ligase-like family, member 7 [Homo ... 91 5e-18
gi|75677580 tubulin tyrosine ligase-like family, member 13 [Homo... 91 5e-18
gi|195963418 tubulin tyrosine ligase-like family, member 6 isofo... 84 4e-16
gi|212720861 tubulin tyrosine ligase-like family, member 11 a [H... 71 4e-12
gi|194239678 tubulin tyrosine ligase-like family, member 10 isof... 63 1e-09
gi|89363028 tubulin tyrosine ligase-like family, member 11 b [Ho... 57 5e-08
gi|11056036 tubulin tyrosine ligase-like family, member 12 [Homo... 49 2e-05
gi|195963416 tubulin tyrosine ligase-like family, member 6 isofo... 38 0.031
gi|163914392 glioma tumor suppressor candidate region gene 1 [Ho... 34 0.59
gi|58331272 zinc finger, CCHC domain containing 6 [Homo sapiens] 33 1.0
gi|73747887 ADAM metallopeptidase domain 12 isoform 2 preproprot... 32 2.2
gi|73747885 ADAM metallopeptidase domain 12 isoform 1 preproprot... 32 2.2
gi|31543091 MAK16 homolog [Homo sapiens] 32 2.2
gi|20357504 dystonin isoform 1eB precursor [Homo sapiens] 32 2.2
gi|38201677 teashirt family zinc finger 1 [Homo sapiens] 32 2.9
gi|100816397 MYST histone acetyltransferase (monocytic leukemia)... 32 2.9
gi|83641870 nucleophosmin 1 isoform 3 [Homo sapiens] 30 6.5
gi|40353734 nucleophosmin 1 isoform 2 [Homo sapiens] 30 6.5
gi|10835063 nucleophosmin 1 isoform 1 [Homo sapiens] 30 6.5
gi|239747190 PREDICTED: hypothetical protein [Homo sapiens] 30 6.5
gi|169177031 PREDICTED: similar to hCG30082, partial [Homo sapiens] 30 6.5
>gi|109134340 tubulin tyrosine ligase-like family, member 3 [Homo
sapiens]
Length = 772
Score = 1589 bits (4114), Expect = 0.0
Identities = 772/772 (100%), Positives = 772/772 (100%)
Query: 1 MNRLRNAKIYVERAVKQKKIFTIQGCYPVIRCLLRRRGWVEKKMVHRSGPTLLPPQKDLD 60
MNRLRNAKIYVERAVKQKKIFTIQGCYPVIRCLLRRRGWVEKKMVHRSGPTLLPPQKDLD
Sbjct: 1 MNRLRNAKIYVERAVKQKKIFTIQGCYPVIRCLLRRRGWVEKKMVHRSGPTLLPPQKDLD 60
Query: 61 SSAMGDSDTTEDEDEDEDEEFQPSQLFDFDDLLKFDDLDGTHALMVGLCLNLRNLPWFDE 120
SSAMGDSDTTEDEDEDEDEEFQPSQLFDFDDLLKFDDLDGTHALMVGLCLNLRNLPWFDE
Sbjct: 61 SSAMGDSDTTEDEDEDEDEEFQPSQLFDFDDLLKFDDLDGTHALMVGLCLNLRNLPWFDE 120
Query: 121 VDANSFFPRCYCLGAEDDKKAFIEDFWLTAARNVLKLVVKSEWKSYPIQAVEEEASGDKQ 180
VDANSFFPRCYCLGAEDDKKAFIEDFWLTAARNVLKLVVKSEWKSYPIQAVEEEASGDKQ
Sbjct: 121 VDANSFFPRCYCLGAEDDKKAFIEDFWLTAARNVLKLVVKSEWKSYPIQAVEEEASGDKQ 180
Query: 181 PKKQEKNPVLVSPEFVDEALCACEEYLSNLAHMDIDKDLEAPLYLTPEGWSLFLQRYYQV 240
PKKQEKNPVLVSPEFVDEALCACEEYLSNLAHMDIDKDLEAPLYLTPEGWSLFLQRYYQV
Sbjct: 181 PKKQEKNPVLVSPEFVDEALCACEEYLSNLAHMDIDKDLEAPLYLTPEGWSLFLQRYYQV 240
Query: 241 VHEGAELRHLDTQVQRCEDILQQLQAVVPQIDMEGDRNIWIVKPGAKSRGRGIMCMDHLE 300
VHEGAELRHLDTQVQRCEDILQQLQAVVPQIDMEGDRNIWIVKPGAKSRGRGIMCMDHLE
Sbjct: 241 VHEGAELRHLDTQVQRCEDILQQLQAVVPQIDMEGDRNIWIVKPGAKSRGRGIMCMDHLE 300
Query: 301 EMLKLVNGNPVVMKDGKWVVQKYIERPLLIFGTKFDLRQWFLVTDWNPLTVWFYRDSYIR 360
EMLKLVNGNPVVMKDGKWVVQKYIERPLLIFGTKFDLRQWFLVTDWNPLTVWFYRDSYIR
Sbjct: 301 EMLKLVNGNPVVMKDGKWVVQKYIERPLLIFGTKFDLRQWFLVTDWNPLTVWFYRDSYIR 360
Query: 361 FSTQPFSLKNLDNSVHLCNNSIQKHLENSCHRHPLLPPDNMWSSQRFQAHLQEMGAPNAW 420
FSTQPFSLKNLDNSVHLCNNSIQKHLENSCHRHPLLPPDNMWSSQRFQAHLQEMGAPNAW
Sbjct: 361 FSTQPFSLKNLDNSVHLCNNSIQKHLENSCHRHPLLPPDNMWSSQRFQAHLQEMGAPNAW 420
Query: 421 STIIVPGMKDAVIHALQTSQDTVQCRKASFELYGADFVFGEDFQPWLIEINASPTMAPST 480
STIIVPGMKDAVIHALQTSQDTVQCRKASFELYGADFVFGEDFQPWLIEINASPTMAPST
Sbjct: 421 STIIVPGMKDAVIHALQTSQDTVQCRKASFELYGADFVFGEDFQPWLIEINASPTMAPST 480
Query: 481 AVTARLCAGVQADTLRVVIDRMLDRNCDTGAFELIYKQPAVEVPQYVGIRLLVEGFTIKK 540
AVTARLCAGVQADTLRVVIDRMLDRNCDTGAFELIYKQPAVEVPQYVGIRLLVEGFTIKK
Sbjct: 481 AVTARLCAGVQADTLRVVIDRMLDRNCDTGAFELIYKQPAVEVPQYVGIRLLVEGFTIKK 540
Query: 541 PMAMCHRRMGVRPAVPLLTQRGSGEARHHFPSLHTKAQLPSPHVLRHQGQVLRRQHSKLV 600
PMAMCHRRMGVRPAVPLLTQRGSGEARHHFPSLHTKAQLPSPHVLRHQGQVLRRQHSKLV
Sbjct: 541 PMAMCHRRMGVRPAVPLLTQRGSGEARHHFPSLHTKAQLPSPHVLRHQGQVLRRQHSKLV 600
Query: 601 GTKALSTTGKALRTLPTAKVFISLPPNLDFKVAPSILKPRKAPALLCLRGPQLEVPCCLC 660
GTKALSTTGKALRTLPTAKVFISLPPNLDFKVAPSILKPRKAPALLCLRGPQLEVPCCLC
Sbjct: 601 GTKALSTTGKALRTLPTAKVFISLPPNLDFKVAPSILKPRKAPALLCLRGPQLEVPCCLC 660
Query: 661 PLKSEQFLAPVGRSRPKANSRPDCDKPRAEACPMKRLSPLKPLPLVGTFQRRRGLGDMKL 720
PLKSEQFLAPVGRSRPKANSRPDCDKPRAEACPMKRLSPLKPLPLVGTFQRRRGLGDMKL
Sbjct: 661 PLKSEQFLAPVGRSRPKANSRPDCDKPRAEACPMKRLSPLKPLPLVGTFQRRRGLGDMKL 720
Query: 721 GKPLLRFPTALVLDPTPNKKKQVKYLGLDSIAVGGSRVDGARPCTPGSTARA 772
GKPLLRFPTALVLDPTPNKKKQVKYLGLDSIAVGGSRVDGARPCTPGSTARA
Sbjct: 721 GKPLLRFPTALVLDPTPNKKKQVKYLGLDSIAVGGSRVDGARPCTPGSTARA 772
>gi|122937293 tubulin tyrosine ligase-like family, member 8 [Homo
sapiens]
Length = 834
Score = 462 bits (1190), Expect = e-130
Identities = 253/589 (42%), Positives = 349/589 (59%), Gaps = 67/589 (11%)
Query: 10 YVERAVKQKKIFTIQGCYPVIRCLLRRRGWVEKKMVHRSGPTLLPPQKDLDSSAMGDSDT 69
Y E A +KKIF+I G YPV+R LRR+GWVEKK P ++P +D A + DT
Sbjct: 12 YSENAC-EKKIFSIYGHYPVVRAALRRKGWVEKKFHFL--PKVIPDVED--EGARVNDDT 66
Query: 70 TEDEDEDEDEEFQPSQ-----------------------------LFDFDDLLKFDDLDG 100
E+++ + + +D +L
Sbjct: 67 CAKVKENQEMALEKTDNIHDVMSRLVKNEMPYLLWTIKRDIIDYHSLTYDQMLNHYAKTA 126
Query: 101 THALMVGLCLNLRNLPWFDEVDANSFFPRCYCLGAEDDKKAFIEDFWLTAARNVLKLVVK 160
+ +GLC+N+R+LPW+ + +SFFPRCY L E +++ F+EDF T A ++LK VV
Sbjct: 127 SFTTKIGLCVNMRSLPWYVPANPDSFFPRCYSLCTESEQQEFLEDFRRTMASSILKWVVS 186
Query: 161 SEW-----KSYPIQAVEEEASGDKQPKKQEKNPVL----VSPEFVDEALCACEEYLSNLA 211
+ +S P EE S D ++ +N + + VD A C+ YL L
Sbjct: 187 HQSCSRSSRSKPRDQREEAGSSDLSSRQDAENAEAKLRGLPGQLVDIACKVCQAYLGQLE 246
Query: 212 HMDIDKDLEAPLYLTPEGWSLFLQRYYQVVHE--GAELRHLDTQVQR------------- 256
H DID +A LT W Q+YY +V G+ + ++Q+
Sbjct: 247 HEDIDTSADAVEDLTEAEWEDLTQQYYSLVQVPLGSSIVLCIFKIQKVMMSFEPPTARDR 306
Query: 257 -CEDILQQLQAVVPQIDMEGDRNIWIVKPGAKSRGRG----IMCMDHLEEMLKLVNGNPV 311
C+ +L ++ +V PQ D++G RNIWI+KP AKSRGRG I+CMD +EE+L+L +
Sbjct: 307 QCQALLNRITSVNPQTDIDGLRNIWIIKPAAKSRGRGESPDIVCMDRVEEILELAAADHP 366
Query: 312 VMKDGKWVVQKYIERPLLIFGTKFDLRQWFLVTDWNPLTVWFYRDSYIRFSTQPFSLKNL 371
+ +D KWVVQKYIE PLLI TKFD+RQWFLVTDWNPLT+WFY++SY+RFSTQ FSL L
Sbjct: 367 LSRDNKWVVQKYIETPLLICDTKFDIRQWFLVTDWNPLTIWFYKESYLRFSTQRFSLDKL 426
Query: 372 DNSVHLCNNSIQKHLENSCHRHPLLPPDNMWSSQRFQAHLQEMGAPNAWSTIIVPGMKDA 431
D+++HLCNN++QK+L+N R PLLP NMW+S RFQ +LQ G W ++I P MK A
Sbjct: 427 DSAIHLCNNAVQKYLKNDVGRSPLLPAHNMWTSTRFQEYLQRQGRGAVWGSVIYPSMKKA 486
Query: 432 VIHALQTSQDTVQCRKASFELYGADFVFGEDFQPWLIEINASPTMAPSTAVTARLCAGVQ 491
+ HA++ +QD V+ RK SFELYGADFV G DF+PWLIEIN+SPTM PST VTA+LCA VQ
Sbjct: 487 IAHAMKVAQDHVEPRKNSFELYGADFVLGRDFRPWLIEINSSPTMHPSTPVTAQLCAQVQ 546
Query: 492 ADTLRVVIDRMLDRNCDTGAFELIYKQPAVEVPQYVGIRLLVEGFTIKK 540
DT++V + DR+CD G FEL+++QP VE P + G L V G ++++
Sbjct: 547 EDTIKVAV----DRSCDIGNFELLWRQPVVEPPPFSGSDLCVAGVSVRR 591
>gi|11068135 tubulin tyrosine ligase-like family, member 1 [Homo
sapiens]
Length = 423
Score = 113 bits (282), Expect = 8e-25
Identities = 74/228 (32%), Positives = 115/228 (50%), Gaps = 14/228 (6%)
Query: 280 WIVKPGAKSRGRGIMCMDHLEEMLKLVNGNPV---VMKDGK--WVVQKYIERPLLIFGTK 334
WI+KP K++G+GI ++ L ++ K + V + K +V+ YI PLLI G K
Sbjct: 135 WIMKPCGKAQGKGIFLINKLSQIKKWSRDSKTSSFVSQSNKEAYVISLYINNPLLIGGRK 194
Query: 335 FDLRQWFLVTDWNPLTVWFYRDSYIRFSTQPF--SLKNLDNS-VHLCNNSIQKHLENSCH 391
FDLR + LV+ + PL + Y+ + RF T + S LDN VHL N +IQKH E+ H
Sbjct: 195 FDLRLYVLVSTYRPLRCYMYKLGFCRFCTVKYTPSTSELDNMFVHLTNVAIQKHGEDYNH 254
Query: 392 RHPLLPPDNMWSSQRFQAHLQEMGAPNAWSTIIVPGMKDAVIHALQTSQDTVQCRKASFE 451
H W+ + +L+ S + + ++ +L+ + K FE
Sbjct: 255 IH-----GGKWTVSNLRLYLESTRGKEVTSKLF-DEIHWIIVQSLKAVAPVMNNDKHCFE 308
Query: 452 LYGADFVFGEDFQPWLIEINASPTMAPSTAVTARLCAGVQADTLRVVI 499
YG D + + +PWLIE+NASP++ STA L + DTL + +
Sbjct: 309 CYGYDIIIDDKLKPWLIEVNASPSLTSSTANDRILKYNLINDTLNIAV 356
>gi|50658079 tubulin tyrosine ligase-like family, member 5 [Homo
sapiens]
Length = 1281
Score = 110 bits (275), Expect = 5e-24
Identities = 76/236 (32%), Positives = 119/236 (50%), Gaps = 26/236 (11%)
Query: 276 DRNIWIVKPGAKSRGRGIMCMDHLEEMLKLVNGNPVVMKDGKWVVQKYIERPLLIFGTKF 335
DR WIVKP A SRGRG+ L+N + + +V +YI PLLI KF
Sbjct: 173 DRGPWIVKPVASSRGRGVY----------LINNPNQISLEENILVSRYINNPLLIDDFKF 222
Query: 336 DLRQWFLVTDWNPLTVWFYRDSYIRFSTQPF--SLKNLDNS-VHLCNNSIQKHLEN--SC 390
D+R + LVT ++PL ++ Y + RF+T + KN+ N +HL N S+ K + SC
Sbjct: 223 DVRLYVLVTSYDPLVIYLYEEGLARFATVRYDQGAKNIRNQFMHLTNYSVNKKSGDYVSC 282
Query: 391 HRHPLLPPDNMWSSQRFQAHLQEMGAPNAWSTIIVPGMKDAVIH-------ALQTSQDT- 442
+ N WS +L++ G +T ++ ++D +I A+ T+ T
Sbjct: 283 DDPEVEDYGNKWSMSAMLRYLKQEGRD---TTALMAHVEDLIIKTIISAELAIATACKTF 339
Query: 443 VQCRKASFELYGADFVFGEDFQPWLIEINASPTMAPSTAVTARLCAGVQADTLRVV 498
V R + FELYG D + +PWL+E+N SP++A + ++ A + +D VV
Sbjct: 340 VPHRSSCFELYGFDVLIDSTLKPWLLEVNLSPSLACDAPLDLKIKASMISDMFTVV 395
>gi|99028883 tubulin tyrosine ligase-like family, member 2 [Homo
sapiens]
Length = 592
Score = 104 bits (260), Expect = 3e-22
Identities = 63/198 (31%), Positives = 101/198 (51%), Gaps = 14/198 (7%)
Query: 280 WIVKPGAKSRGRGIMCMDHLEEMLKLVNGNPVVMKDGKWVVQKYIERPLLIFGTKFDLRQ 339
WI KP SRGRGI+ ++ + D ++VQKYI PLLI K DLR
Sbjct: 209 WICKPAELSRGRGILIFSDFKDFIF----------DDMYIVQKYISNPLLIGRYKCDLRI 258
Query: 340 WFLVTDWNPLTVWFYRDSYIRFSTQPFSLKNLDNS-VHLCNNSIQKHLENSCHRHPLLPP 398
+ VT + PLT++ Y++ +RF+T+ F L NL N+ HL N+SI K + ++
Sbjct: 259 YVCVTGFKPLTIYVYQEGLVRFATEKFDLSNLQNNYAHLTNSSINKSGASYEKIKEVIGH 318
Query: 399 DNMWSSQRFQAHLQEMGAPNAWSTIIVPGMKDAVIHALQTSQDTVQCRKASFELYGADFV 458
W+ RF ++L+ + ++ + VI + +V FEL+G D +
Sbjct: 319 GCKWTLSRFFSYLRSWDVDD---LLLWKKIHRMVILTILAIAPSVPFAANCFELFGFDIL 375
Query: 459 FGEDFQPWLIEINASPTM 476
++ +PWL+E+N SP +
Sbjct: 376 IDDNLKPWLLEVNYSPAL 393
>gi|194239681 tubulin tyrosine ligase-like family, member 10 isoform
1 [Homo sapiens]
Length = 673
Score = 101 bits (252), Expect = 2e-21
Identities = 65/242 (26%), Positives = 116/242 (47%), Gaps = 22/242 (9%)
Query: 276 DRNIWIVKPGAKSRGRGIMCMDHLEEMLKL------VNGNPVVMKDG-----KWVVQKYI 324
+ IWI KP A ++G+GI + + EE+ L + +P+ K VVQ+YI
Sbjct: 306 ETQIWICKPTASNQGKGIFLLRNQEEVAALQAKTRSMEDDPIHHKTPFRGPQARVVQRYI 365
Query: 325 ERPLLIFGTKFDLRQWFLVTDWNPLTVWFYRDSYIRFSTQPFSLKNLDNSVHLCNNSIQK 384
+ PLL+ G KFD+R + L+ P + F+ Y R + + + D HL N +QK
Sbjct: 366 QNPLLVDGRKFDVRSYLLIACTTPYMI-FFGHGYARLTLSLYDPHSSDLGGHLTNQFMQK 424
Query: 385 HLENSCHRHPLLPPDNMWSSQRFQAHLQEM-----GAPNAWS-TIIVPGMKDAVIHALQT 438
+ LL +WS + ++ + G W T + M+ + H
Sbjct: 425 ----KSPLYMLLKEHTVWSMEHLNRYISDTFWKARGLAKDWVFTTLKKRMQQIMAHCFLA 480
Query: 439 SQDTVQCRKASFELYGADFVFGEDFQPWLIEINASPTMAPSTAVTARLCAGVQADTLRVV 498
++ + C+ F+L G DF+ ++F+ WL+E+N++P + + V + GV +TL +V
Sbjct: 481 AKPKLDCKLGYFDLIGCDFLIDDNFKVWLLEMNSNPALHTNCEVLKEVIPGVVIETLDLV 540
Query: 499 ID 500
++
Sbjct: 541 LE 542
>gi|56606131 tubulin tyrosine ligase-like family, member 9 [Homo
sapiens]
Length = 439
Score = 99.4 bits (246), Expect = 1e-20
Identities = 78/251 (31%), Positives = 119/251 (47%), Gaps = 30/251 (11%)
Query: 280 WIVKPGAKSRGRGIMCMDHLEEML--KLVNGNPVVMKDG----KWVVQKYIERPLLIFGT 333
WI+KP A+S+G+GI L++++ + + KD +V Q+YIE P LI G
Sbjct: 164 WIMKPVARSQGKGIFLFRRLKDIVDWRKDTRSSDDQKDDIPVENYVAQRYIENPYLIGGR 223
Query: 334 KFDLRQWFLVTD-WNPLTVWFYRDSYIRFSTQPFSLKNLDNSVHLCNNSIQKHLENSCHR 392
KFDLR + LV + +W + VHL N ++QK S
Sbjct: 224 KFDLRVYVLVMSVFAECLLWS---------------GHRRQDVHLTNVAVQK---TSPDY 265
Query: 393 HPLLPPDNMWSSQRFQAHLQEMGAPNAWSTIIVPGMKDAVIHALQTSQDTVQCRKASFEL 452
HP W+ QRF+ +L P A T+ + + + +LQ+ Q + K FEL
Sbjct: 266 HP--KKGCKWTLQRFRQYLASKHGPEAVETLF-RDIDNIFVKSLQSVQKVIISDKHCFEL 322
Query: 453 YGADFVFGEDFQPWLIEINASPTMAPSTAVTARLCAGVQADTLRVV--IDRMLDRNCDTG 510
YG D + +D +PWL+E+NASP++ S+ L + DTL VV R+ R G
Sbjct: 323 YGYDILIDQDLKPWLLEVNASPSLTASSQEDYELKTCLLEDTLHVVDMEARLTGREKRVG 382
Query: 511 AFELIYKQPAV 521
F+L++ V
Sbjct: 383 GFDLMWNDGPV 393
>gi|24308516 tubulin tyrosine ligase [Homo sapiens]
Length = 377
Score = 97.8 bits (242), Expect = 3e-20
Identities = 64/223 (28%), Positives = 113/223 (50%), Gaps = 19/223 (8%)
Query: 274 EGDRNIWIVKPGAKSRGRGIMCMDHLEEMLKLVNGNPVVMKDGKWVVQKYIERPLLIFG- 332
+G+ N+WI K A ++G GI+ E+L ++ V V+QKY+E PLL+
Sbjct: 141 DGEGNVWIAKSSAGAKGEGILISSEASELLDFIDNQGQVH-----VIQKYLEHPLLLEPG 195
Query: 333 -TKFDLRQWFLVTDWNPLTVWFYRDSYIRFSTQPFSLKNL-DNSVHLCNNSIQKHLENSC 390
KFD+R W LV + ++ YR+ +R +++P+ + N D + HL N+ IQK +
Sbjct: 196 HRKFDIRSWVLVD--HQYNIYLYREGVLRTASEPYHVDNFQDKTCHLTNHCIQKEYSKNY 253
Query: 391 HRHPLLPPDNMWSSQRFQAHLQEMGAPNAWSTIIVPGMKDAVIHALQTSQDTVQCRKA-- 448
++ N + F +L S+I++ +K + + L + + + +
Sbjct: 254 GKYE---EGNEMFFKEFNQYLTSALNITLESSILLQ-IKHIIRNCLLSVEPAISTKHLPY 309
Query: 449 -SFELYGADFVFGEDFQPWLIEINASPTMAPSTAVTARLCAGV 490
SF+L+G DF+ E+ + WLIE+N +P A + A LC G+
Sbjct: 310 QSFQLFGFDFMVDEELKVWLIEVNGAPACAQK--LYAELCQGI 350
>gi|217330594 tubulin tyrosine ligase-like family, member 4 [Homo
sapiens]
Length = 1199
Score = 96.3 bits (238), Expect = 1e-19
Identities = 66/233 (28%), Positives = 119/233 (51%), Gaps = 25/233 (10%)
Query: 277 RNIWIVKPGAKSRGRGIMCMDHLEEMLKLVNGNPVVMKDGKWVVQKYIERPLLIFGTKFD 336
R WIVKP A +RG GI + ++ K P++ VQ+Y+ +P LI G+KFD
Sbjct: 715 RQKWIVKPPASARGIGIQVIHKWSQLPKR---RPLL-------VQRYLHKPYLISGSKFD 764
Query: 337 LRQWFLVTDWNPLTVWFYRDSYIRFSTQPF--SLKNLDNS-VHLCNNSI-QKHLENSCHR 392
LR + VT ++PL ++ + D +RF++ + S+K+L N +HL N S+ +K+ E +
Sbjct: 765 LRIYVYVTSYDPLRIYLFSDGLVRFASCKYSPSMKSLGNKFMHLTNYSVNKKNAEYQANA 824
Query: 393 HPLLPPDNMWSSQRFQAHLQEMGAPNAWSTIIVPGMKDAVIHALQTSQDTVQCRKASF-- 450
+ + W+ + +L + G S I +KD V+ + +S+ V +
Sbjct: 825 DEMACQGHKWALKALWNYLSQKGVN---SDAIWEKIKDVVVKTIISSEPYVTSLLKMYVR 881
Query: 451 ------ELYGADFVFGEDFQPWLIEINASPTMAPSTAVTARLCAGVQADTLRV 497
EL+G D + E+ +PW++E+N SP++ S+ + + + D L +
Sbjct: 882 RPYSCHELFGFDIMLDENLKPWVLEVNISPSLHSSSPLDISIKGQMIRDLLNL 934
>gi|94536793 tubulin tyrosine ligase-like family, member 7 [Homo
sapiens]
Length = 887
Score = 90.5 bits (223), Expect = 5e-18
Identities = 70/263 (26%), Positives = 116/263 (44%), Gaps = 37/263 (14%)
Query: 263 QLQAVVPQIDMEGDRNIWIVKPGAKSRGRGIMCMDHLEEMLKLVNGNPVVMKDGKWVVQK 322
Q Q V ++ + + +IVKP + G GI + NG+ + +D +VQ+
Sbjct: 140 QFQNYVKELKKKRKQKTFIVKPANGAMGHGISLIR---------NGDKLPSQD-HLIVQE 189
Query: 323 YIERPLLIFGTKFDLRQWFLVTDWNPLTVWFYRDSYIRFSTQPFSLKNLDN----SVHLC 378
YIE+P L+ G KFDLR + LVT +PL ++ Y D +R T+ + N N +HL
Sbjct: 190 YIEKPFLMEGYKFDLRIYILVTSCDPLKIFLYHDGLVRMGTEKYIPPNESNLTQLYMHLT 249
Query: 379 NNSIQKH--------LENSCHRHPLLPPDNMWSSQRFQAHLQEMGAPNAWSTIIVPGMKD 430
N S+ KH EN + + W ++ QA+ ++ WS I +K
Sbjct: 250 NYSVNKHNEHFERDETENKGSKRSI-----KWFTEFLQANQHDVA--KFWSDISELVVKT 302
Query: 431 AVIHALQTSQDTVQCR--------KASFELYGADFVFGEDFQPWLIEINASPTMAPSTAV 482
++ CR FE+ G D + +PWL+EIN +P+ +
Sbjct: 303 LIVAEPHVLHAYRMCRPGQPPGSESVCFEVLGFDILLDRKLKPWLLEINRAPSFGTDQKI 362
Query: 483 TARLCAGVQADTLRVVIDRMLDR 505
+ GV + L+++ R D+
Sbjct: 363 DYDVKRGVLLNALKLLNIRTSDK 385
>gi|75677580 tubulin tyrosine ligase-like family, member 13 [Homo
sapiens]
Length = 459
Score = 90.5 bits (223), Expect = 5e-18
Identities = 71/249 (28%), Positives = 114/249 (45%), Gaps = 45/249 (18%)
Query: 280 WIVKPGAKSRGRGIMCMDHLEEMLKLVNGNPVVMKDGKWVV-QKYIERPLLIFGTKFDLR 338
+I KP + +GRGI + NP +K G+ ++ Q+YI +PLLI G KFD+R
Sbjct: 199 YICKPDSGCQGRGIF-----------ITRNPREIKPGEHMICQQYISKPLLIDGFKFDMR 247
Query: 339 QWFLVTDWNPLTVWFYRDSYIRFSTQPF---SLKNLDN-SVHLCNNSIQKHLENSCHRHP 394
+ L+T +PL ++ Y + RF+T P+ S NLDN +HL N +I KH EN
Sbjct: 248 VYVLITSCDPLRIFTYEEGLARFATTPYMEPSHNNLDNVCMHLTNYAINKHNENFVRDGA 307
Query: 395 L-----LPPDNMWSSQRFQAHLQEMGAPNAWSTIIVPGMKDAVIHALQTSQDTVQCRK-- 447
+ L N+W Q H G W I +D +I + ++ ++
Sbjct: 308 VGSKRKLSTLNIW----LQEHSYNPG--ELWGDI-----EDIIIKTIISAHSVLRHNYRT 356
Query: 448 -----------ASFELYGADFVFGEDFQPWLIEINASPTMAPSTAVTARLCAGVQADTLR 496
A FE+ G D + +PWL+E+N SP+ + + + + D +
Sbjct: 357 CFPQYLNGGTCACFEILGFDILLDHKLKPWLLEVNHSPSFTTDSCLDQEVKDALLCDAMT 416
Query: 497 VVIDRMLDR 505
+V R D+
Sbjct: 417 LVNLRGCDK 425
>gi|195963418 tubulin tyrosine ligase-like family, member 6 isoform
1 [Homo sapiens]
Length = 891
Score = 84.3 bits (207), Expect = 4e-16
Identities = 67/236 (28%), Positives = 107/236 (45%), Gaps = 35/236 (14%)
Query: 280 WIVKPGAKSRGRGIMCMDHLEEMLKLVNGNPVVMKDGK-WVVQKYIERPLLIFGTKFDLR 338
+I KP + +G+GI ++E+ K G+ + Q YI +P +I G KFDLR
Sbjct: 220 YICKPDSGCQGKGIFITRTVKEI-----------KPGEDMICQLYISKPFIIDGFKFDLR 268
Query: 339 QWFLVTDWNPLTVWFYRDSYIRFSTQPFSLKNLDN----SVHLCNNSIQKHLENSCHRHP 394
+ LVT +PL ++ Y + RF+T +S DN +HL N SI KH N
Sbjct: 269 IYVLVTSCDPLRIFVYNEGLARFATTSYSRPCTDNLDDICMHLTNYSINKHSSN------ 322
Query: 395 LLPPDNMWSSQR----FQAHLQE--MGAPNAW---STIIVPGMKDA---VIHALQTSQDT 442
D S+R F A+L++ W +I+ + A + H T
Sbjct: 323 -FSRDAHSGSKRKLSTFSAYLEDHSYNVEQIWRDIEDVIIKTLISAHPIIRHNYHTCFPN 381
Query: 443 VQCRKASFELYGADFVFGEDFQPWLIEINASPTMAPSTAVTARLCAGVQADTLRVV 498
A FE+ G D + +PWL+E+N SP+ + + + + G+ DTL ++
Sbjct: 382 HTLNSACFEILGFDILLDHKLKPWLLEVNHSPSFSTDSRLDKEVKDGLLYDTLVLI 437
>gi|212720861 tubulin tyrosine ligase-like family, member 11 a [Homo
sapiens]
Length = 800
Score = 70.9 bits (172), Expect = 4e-12
Identities = 63/230 (27%), Positives = 106/230 (46%), Gaps = 21/230 (9%)
Query: 263 QLQAVVPQIDMEGD-----RNIWIVKPGAKSRGRGIMCMDHLEEMLKLVNGNPVVMKDGK 317
+ Q V Q+ M D + +IVKP +G GI + + ++L ++
Sbjct: 314 EFQLFVAQVQMVKDDDPSWKPTFIVKPDGGCQGDGIYLIKDPSD-IRLAG----TLQSRP 368
Query: 318 WVVQKYIERPLLIFGTKFDLRQWFLVTDWNPLTVWFYRDSYIRFSTQPF---SLKNLDN- 373
VVQ+YI +PLLI KFD+R + L+ +PL ++ +D RF T+P+ + KNL
Sbjct: 369 AVVQEYICKPLLIDKLKFDIRLYVLLKSLDPLEIYIAKDGLSRFCTEPYQEPTPKNLHRI 428
Query: 374 SVHLCNNSIQKHLENSCHRHPL-LPPDNMWSSQRFQAHLQEMGAPNAWSTIIVPGMKDAV 432
+HL N S+ H N H +SS + + + WS II +K +
Sbjct: 429 FMHLTNYSLNIHSGNFIHSDSASTGSKRTFSSILCRLSSKGVDIKKVWSDIISVVIKTVI 488
Query: 433 IHA------LQTSQDTVQCRKASFELYGADFVFGEDFQPWLIEINASPTM 476
Q+ T + F++ G D + ++ +P L+E+NA+P+M
Sbjct: 489 ALTPELKVFYQSDIPTGRPGPTCFQILGFDILLMKNLKPILLEVNANPSM 538
>gi|194239678 tubulin tyrosine ligase-like family, member 10 isoform
2 [Homo sapiens]
Length = 404
Score = 62.8 bits (151), Expect = 1e-09
Identities = 42/149 (28%), Positives = 70/149 (46%), Gaps = 16/149 (10%)
Query: 276 DRNIWIVKPGAKSRGRGIMCMDHLEEMLKL------VNGNPVVMKDG-----KWVVQKYI 324
+ IWI KP A ++G+GI + + EE+ L + +P+ K VVQ+YI
Sbjct: 233 ETQIWICKPTASNQGKGIFLLRNQEEVAALQAKTRSMEDDPIHHKTPFRGPQARVVQRYI 292
Query: 325 ERPLLIFGTKFDLRQWFLVTDWNPLTVWFYRDSYIRFSTQPFSLKNLDNSVHLCNNSIQK 384
+ PLL+ G KFD+R + L+ P + F+ Y R + + + D HL N +QK
Sbjct: 293 QNPLLVDGRKFDVRSYLLIACTTPYMI-FFGHGYARLTLSLYDPHSSDLGGHLTNQFMQK 351
Query: 385 HLENSCHRHPLLPPDNMWSSQRFQAHLQE 413
+ LL +WS + ++ +
Sbjct: 352 ----KSPLYMLLKEHTVWSMEHLNRYISD 376
>gi|89363028 tubulin tyrosine ligase-like family, member 11 b [Homo
sapiens]
Length = 538
Score = 57.4 bits (137), Expect = 5e-08
Identities = 44/138 (31%), Positives = 69/138 (50%), Gaps = 14/138 (10%)
Query: 263 QLQAVVPQIDMEGD-----RNIWIVKPGAKSRGRGIMCMDHLEEMLKLVNGNPVVMKDGK 317
+ Q V Q+ M D + +IVKP +G GI + + ++L ++
Sbjct: 314 EFQLFVAQVQMVKDDDPSWKPTFIVKPDGGCQGDGIYLIKDPSD-IRLAG----TLQSRP 368
Query: 318 WVVQKYIERPLLIFGTKFDLRQWFLVTDWNPLTVWFYRDSYIRFSTQPF---SLKNLDN- 373
VVQ+YI +PLLI KFD+R + L+ +PL ++ +D RF T+P+ + KNL
Sbjct: 369 AVVQEYICKPLLIDKLKFDIRLYVLLKSLDPLEIYIAKDGLSRFCTEPYQEPTPKNLHRI 428
Query: 374 SVHLCNNSIQKHLENSCH 391
+HL N S+ H N H
Sbjct: 429 FMHLTNYSLNIHSGNFIH 446
>gi|11056036 tubulin tyrosine ligase-like family, member 12 [Homo
sapiens]
Length = 644
Score = 48.5 bits (114), Expect = 2e-05
Identities = 35/118 (29%), Positives = 53/118 (44%), Gaps = 12/118 (10%)
Query: 261 LQQLQAVVPQIDMEGDRNIWIVKPGAKSRGRGIMCMDHLEEMLKLVNGNPVVMKDGKWVV 320
L Q + Q + G+ N WI KP +R L +++ P V V
Sbjct: 397 LPQFVSYFQQRERWGEDNHWICKPWNLARSLDTHVTKSLHSIIRHRESTPKV-------V 449
Query: 321 QKYIERPLLIFG-----TKFDLRQWFLVTDWNPLTVWFYRDSYIRFSTQPFSLKNLDN 373
KYIE P+L KFD+R L+ PL ++ Y ++RFS + F+L +LD+
Sbjct: 450 SKYIESPVLFLREDVGKVKFDIRYIVLLRSVRPLRLFVYDVFWLRFSNRAFALNDLDD 507
>gi|195963416 tubulin tyrosine ligase-like family, member 6 isoform
2 [Homo sapiens]
Length = 584
Score = 38.1 bits (87), Expect = 0.031
Identities = 16/51 (31%), Positives = 29/51 (56%)
Query: 448 ASFELYGADFVFGEDFQPWLIEINASPTMAPSTAVTARLCAGVQADTLRVV 498
A FE+ G D + +PWL+E+N SP+ + + + + G+ DTL ++
Sbjct: 80 ACFEILGFDILLDHKLKPWLLEVNHSPSFSTDSRLDKEVKDGLLYDTLVLI 130
>gi|163914392 glioma tumor suppressor candidate region gene 1 [Homo
sapiens]
Length = 1560
Score = 33.9 bits (76), Expect = 0.59
Identities = 33/129 (25%), Positives = 54/129 (41%), Gaps = 15/129 (11%)
Query: 604 ALSTTGKALRTLPTAKVFISLPPNLDFKVAPSILKPRKAPALLCLRGPQLEVPCCLCPLK 663
A +T + + P+A ++ P L P+ AP L PQ P PL
Sbjct: 578 AATTVLQGVTLPPSAVAMLNTPDGLVQPATPAAATGEAAPVLTVQPAPQAP-PAVSTPL- 635
Query: 664 SEQFLAPVGRSRPKANSRPDCDKPRAEACPMKRLSPLKPLPLVGTFQRRRGLGDMKLGKP 723
P+G +P+A P P+A A P + +P +P P + + + + LG+P
Sbjct: 636 ------PLGLQQPQAQQPPQAPTPQA-AAPPQATTP-QPSPGLASSPEK-----IVLGQP 682
Query: 724 LLRFPTALV 732
PTA++
Sbjct: 683 PSATPTAIL 691
>gi|58331272 zinc finger, CCHC domain containing 6 [Homo sapiens]
Length = 1495
Score = 33.1 bits (74), Expect = 1.0
Identities = 18/46 (39%), Positives = 28/46 (60%), Gaps = 4/46 (8%)
Query: 61 SSAMGDSDTTEDEDEDEDEEFQP----SQLFDFDDLLKFDDLDGTH 102
+S M SD E++DE+E+EE +P +Q D D + D+LD T+
Sbjct: 838 TSEMIPSDEEEEDDEEEEEEEEPRLTINQREDEDGMANEDELDNTY 883
>gi|73747887 ADAM metallopeptidase domain 12 isoform 2 preproprotein
[Homo sapiens]
Length = 738
Score = 32.0 bits (71), Expect = 2.2
Identities = 25/85 (29%), Positives = 39/85 (45%), Gaps = 8/85 (9%)
Query: 516 YKQPAVEVPQYVGIRLLV----EGFTIKKPMAMCHRRMGVRPAVPLLTQRGSGEARHHFP 571
Y AV + G+R L+ E + ++ PM R + PA L + RGS + H+ P
Sbjct: 128 YSDSAVSLSTCSGLRGLIVFENESYVLE-PMKSATNRYKLFPAKKLKSVRGSCGSHHNTP 186
Query: 572 SLHTKAQLPSPH---VLRHQGQVLR 593
+L K P P RH+ + L+
Sbjct: 187 NLAAKNVFPPPSQTWARRHKRETLK 211
>gi|73747885 ADAM metallopeptidase domain 12 isoform 1 preproprotein
[Homo sapiens]
Length = 909
Score = 32.0 bits (71), Expect = 2.2
Identities = 25/85 (29%), Positives = 39/85 (45%), Gaps = 8/85 (9%)
Query: 516 YKQPAVEVPQYVGIRLLV----EGFTIKKPMAMCHRRMGVRPAVPLLTQRGSGEARHHFP 571
Y AV + G+R L+ E + ++ PM R + PA L + RGS + H+ P
Sbjct: 128 YSDSAVSLSTCSGLRGLIVFENESYVLE-PMKSATNRYKLFPAKKLKSVRGSCGSHHNTP 186
Query: 572 SLHTKAQLPSPH---VLRHQGQVLR 593
+L K P P RH+ + L+
Sbjct: 187 NLAAKNVFPPPSQTWARRHKRETLK 211
>gi|31543091 MAK16 homolog [Homo sapiens]
Length = 300
Score = 32.0 bits (71), Expect = 2.2
Identities = 18/59 (30%), Positives = 28/59 (47%), Gaps = 7/59 (11%)
Query: 45 VHRSGPTLLPPQKDLDSSAMGDSDTTEDEDED-------EDEEFQPSQLFDFDDLLKFD 96
+H L + + DSS + D +D++ED ED E S + DF+D+ K D
Sbjct: 183 IHAFDKALEQQEAESDSSDTEEKDDDDDDEEDVGKREFVEDGEVDESDISDFEDMDKLD 241
>gi|20357504 dystonin isoform 1eB precursor [Homo sapiens]
Length = 3062
Score = 32.0 bits (71), Expect = 2.2
Identities = 17/49 (34%), Positives = 24/49 (48%), Gaps = 4/49 (8%)
Query: 58 DLDSSAMGDSDTTEDEDEDEDEEFQPSQLFDFDD----LLKFDDLDGTH 102
D ++S + D D D D++F + LF+ DD LL DD D H
Sbjct: 2052 DYETSLLNDQQNNTGTDTDSDDDFYDTPLFEDDDHDSLLLDGDDRDCLH 2100
>gi|38201677 teashirt family zinc finger 1 [Homo sapiens]
Length = 1032
Score = 31.6 bits (70), Expect = 2.9
Identities = 17/45 (37%), Positives = 29/45 (64%), Gaps = 4/45 (8%)
Query: 55 PQKDLDSSAMGDSDTTEDEDEDEDEEFQPSQLFDFDDLLKFDDLD 99
P+K+ A GD++ ++E ED E+F+PS L+ + L+ +DLD
Sbjct: 457 PEKEKPPVA-GDAEKIKEESEDSLEKFEPSTLYPY---LREEDLD 497
>gi|100816397 MYST histone acetyltransferase (monocytic leukemia) 4
[Homo sapiens]
Length = 2073
Score = 31.6 bits (70), Expect = 2.9
Identities = 47/173 (27%), Positives = 75/173 (43%), Gaps = 22/173 (12%)
Query: 61 SSAMGDSDTTEDEDEDEDEEFQPSQLFDFDDLLKFDDLDGTHALMVGLCLNLRNLP--WF 118
S+ DS +D +E+E+E+ +PS D D DD D +H M + LP F
Sbjct: 1396 STEKEDSARLDDHEEEEEEDEEPSHNEDHD----ADDEDDSH--MESAEVEKEELPRESF 1449
Query: 119 DEVDAN--SFFPRCYCLGAEDDKKAFIEDFWLTAARNVLKLVVKSEWKSYPIQAVEEEAS 176
EV N +F G + + LTA+ N + + ++ P ++ EE
Sbjct: 1450 KEVLENQETFLDLNVQPGHSNPEVLMDCGVDLTASCNSEPKELAGDPEAVP-ESDEEPPP 1508
Query: 177 GDKQPKKQEKNPVLVSPEFVDEALCACEEYLSNLAHMDIDKD-LEAPLYLTPE 228
G++ K+ +KN V EF + N A M+ID + ++A LT E
Sbjct: 1509 GEQAQKQDQKNSKEVDTEFKE----------GNPATMEIDSETVQAVQSLTQE 1551
>gi|83641870 nucleophosmin 1 isoform 3 [Homo sapiens]
Length = 259
Score = 30.4 bits (67), Expect = 6.5
Identities = 15/37 (40%), Positives = 22/37 (59%), Gaps = 5/37 (13%)
Query: 55 PQKDLDSSAMGDSDTTEDEDEDEDEEFQPSQLFDFDD 91
PQK + +A D D ++ED+DED++ DFDD
Sbjct: 152 PQKKVKLAADEDDDDDDEEDDDEDDDDD-----DFDD 183
>gi|40353734 nucleophosmin 1 isoform 2 [Homo sapiens]
Length = 265
Score = 30.4 bits (67), Expect = 6.5
Identities = 15/37 (40%), Positives = 22/37 (59%), Gaps = 5/37 (13%)
Query: 55 PQKDLDSSAMGDSDTTEDEDEDEDEEFQPSQLFDFDD 91
PQK + +A D D ++ED+DED++ DFDD
Sbjct: 152 PQKKVKLAADEDDDDDDEEDDDEDDDDD-----DFDD 183
>gi|10835063 nucleophosmin 1 isoform 1 [Homo sapiens]
Length = 294
Score = 30.4 bits (67), Expect = 6.5
Identities = 15/37 (40%), Positives = 22/37 (59%), Gaps = 5/37 (13%)
Query: 55 PQKDLDSSAMGDSDTTEDEDEDEDEEFQPSQLFDFDD 91
PQK + +A D D ++ED+DED++ DFDD
Sbjct: 152 PQKKVKLAADEDDDDDDEEDDDEDDDDD-----DFDD 183
>gi|239747190 PREDICTED: hypothetical protein [Homo sapiens]
Length = 263
Score = 30.4 bits (67), Expect = 6.5
Identities = 18/55 (32%), Positives = 28/55 (50%), Gaps = 4/55 (7%)
Query: 650 GPQLEVPCCLCPLKSEQFLAPVGRSRPKANSRPDCDKPRAEACPMKRLSPLKPLP 704
GPQLE P C PL A G+ +P+ +P+ ++ R + P + L K +P
Sbjct: 146 GPQLEAPRCSPPLHCR---AQGGQEQPQQQQKPNWERNRGKN-PHRLLGTYKEMP 196
>gi|169177031 PREDICTED: similar to hCG30082, partial [Homo sapiens]
Length = 299
Score = 30.4 bits (67), Expect = 6.5
Identities = 23/77 (29%), Positives = 30/77 (38%), Gaps = 8/77 (10%)
Query: 628 LDFKVAPSILKPRKAPALLCLRGPQLEVPCCLCPLKS-------EQFLAPVGRSRPKANS 680
L P+ P +PALL R +++ C CP + F + R R
Sbjct: 16 LSMAAIPTYPCPAVSPALLLPRPERVKQCCQPCPRRDLLASWPCRLFSSETPRPRDCETP 75
Query: 681 RP-DCDKPRAEACPMKR 696
RP DCD PR C R
Sbjct: 76 RPRDCDTPRPRDCETPR 92
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.321 0.137 0.429
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 32,474,451
Number of Sequences: 37866
Number of extensions: 1607196
Number of successful extensions: 7063
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 17
Number of HSP's successfully gapped in prelim test: 23
Number of HSP's that attempted gapping in prelim test: 6904
Number of HSP's gapped (non-prelim): 145
length of query: 772
length of database: 18,247,518
effective HSP length: 110
effective length of query: 662
effective length of database: 14,082,258
effective search space: 9322454796
effective search space used: 9322454796
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.