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Search of human proteins with 4557729
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|4557729 voltage-gated potassium channel, subfamily H, member
2 isoform a [Homo sapiens]
(1159 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|4557729 voltage-gated potassium channel, subfamily H, member ... 2346 0.0
gi|26051271 voltage-gated potassium channel, subfamily H, member... 1611 0.0
gi|26051273 voltage-gated potassium channel, subfamily H, member... 1598 0.0
gi|27886653 potassium voltage-gated channel, subfamily H, member... 1234 0.0
gi|27886665 potassium voltage-gated channel, subfamily H, member... 930 0.0
gi|13540549 potassium voltage-gated channel, subfamily H, member... 926 0.0
gi|27886651 potassium voltage-gated channel, subfamily H, member... 813 0.0
gi|6912446 potassium voltage-gated channel, subfamily H, member ... 478 e-134
gi|27886667 potassium voltage-gated channel, subfamily H, member... 477 e-134
gi|4504831 potassium voltage-gated channel, subfamily H, member ... 471 e-132
gi|22024390 potassium voltage-gated channel, subfamily H, member... 463 e-130
gi|27886648 potassium voltage-gated channel, subfamily H, member... 463 e-130
gi|27437001 potassium voltage-gated channel, subfamily H, member... 461 e-129
gi|38569493 potassium voltage-gated channel, subfamily H (eag-re... 448 e-125
gi|27886646 potassium voltage-gated channel, subfamily H, member... 409 e-114
gi|116325989 hyperpolarization activated cyclic nucleotide-gated... 175 3e-43
gi|4885407 hyperpolarization activated cyclic nucleotide-gated p... 174 3e-43
gi|156071470 hyperpolarization activated cyclic nucleotide-gated... 173 1e-42
gi|38327037 hyperpolarization activated cyclic nucleotide-gated ... 171 3e-42
gi|120433600 cyclic nucleotide gated channel alpha 3 isoform 2 [... 157 4e-38
gi|4502917 cyclic nucleotide gated channel alpha 3 isoform 1 [Ho... 157 4e-38
gi|217035093 cyclic nucleotide gated channel alpha 1 isoform 1 [... 148 3e-35
gi|71143141 cyclic nucleotide gated channel alpha 1 isoform 2 [H... 148 3e-35
gi|42718011 cyclic nucleotide gated channel alpha 2 [Homo sapiens] 140 9e-33
gi|82617546 cyclic nucleotide gated channel alpha 4 [Homo sapiens] 133 9e-31
gi|116642889 cyclic nucleotide gated channel beta 3 [Homo sapiens] 100 1e-20
gi|114205399 cyclic nucleotide gated channel beta 1 isoform a [H... 98 4e-20
gi|34365793 WNK lysine deficient protein kinase 4 [Homo sapiens] 48 5e-05
gi|5031767 heat shock transcription factor 1 [Homo sapiens] 46 2e-04
gi|58530876 melanoma antigen family C, 1 [Homo sapiens] 44 9e-04
>gi|4557729 voltage-gated potassium channel, subfamily H, member 2
isoform a [Homo sapiens]
Length = 1159
Score = 2346 bits (6079), Expect = 0.0
Identities = 1159/1159 (100%), Positives = 1159/1159 (100%)
Query: 1 MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVM 60
MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVM
Sbjct: 1 MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVM 60
Query: 61 QRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDG 120
QRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDG
Sbjct: 61 QRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDG 120
Query: 121 AVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSV 180
AVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSV
Sbjct: 121 AVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSV 180
Query: 181 RSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSP 240
RSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSP
Sbjct: 181 RSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSP 240
Query: 241 PRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPP 300
PRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPP
Sbjct: 241 PRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPP 300
Query: 301 RHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIA 360
RHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIA
Sbjct: 301 RHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIA 360
Query: 361 PKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIY 420
PKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIY
Sbjct: 361 PKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIY 420
Query: 421 TAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANE 480
TAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANE
Sbjct: 421 TAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANE 480
Query: 481 EVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLD 540
EVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLD
Sbjct: 481 EVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLD 540
Query: 541 RYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSS 600
RYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSS
Sbjct: 541 RYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSS 600
Query: 601 GLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVS 660
GLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVS
Sbjct: 601 GLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVS 660
Query: 661 AIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGF 720
AIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGF
Sbjct: 661 AIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGF 720
Query: 721 PECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALY 780
PECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALY
Sbjct: 721 PECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALY 780
Query: 781 FISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLE 840
FISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLE
Sbjct: 781 FISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLE 840
Query: 841 VLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTE 900
VLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTE
Sbjct: 841 VLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTE 900
Query: 901 QPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSS 960
QPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSS
Sbjct: 901 QPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSS 960
Query: 961 PRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTP 1020
PRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTP
Sbjct: 961 PRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTP 1020
Query: 1021 SLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSA 1080
SLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSA
Sbjct: 1021 SLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSA 1080
Query: 1081 VTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPG 1140
VTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPG
Sbjct: 1081 VTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPG 1140
Query: 1141 QLGALTSQPLHRHGSDPGS 1159
QLGALTSQPLHRHGSDPGS
Sbjct: 1141 QLGALTSQPLHRHGSDPGS 1159
>gi|26051271 voltage-gated potassium channel, subfamily H, member 2
isoform b [Homo sapiens]
Length = 888
Score = 1611 bits (4172), Expect = 0.0
Identities = 800/800 (100%), Positives = 800/800 (100%)
Query: 1 MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVM 60
MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVM
Sbjct: 1 MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVM 60
Query: 61 QRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDG 120
QRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDG
Sbjct: 61 QRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDG 120
Query: 121 AVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSV 180
AVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSV
Sbjct: 121 AVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSV 180
Query: 181 RSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSP 240
RSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSP
Sbjct: 181 RSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSP 240
Query: 241 PRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPP 300
PRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPP
Sbjct: 241 PRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPP 300
Query: 301 RHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIA 360
RHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIA
Sbjct: 301 RHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIA 360
Query: 361 PKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIY 420
PKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIY
Sbjct: 361 PKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIY 420
Query: 421 TAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANE 480
TAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANE
Sbjct: 421 TAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANE 480
Query: 481 EVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLD 540
EVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLD
Sbjct: 481 EVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLD 540
Query: 541 RYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSS 600
RYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSS
Sbjct: 541 RYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSS 600
Query: 601 GLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVS 660
GLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVS
Sbjct: 601 GLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVS 660
Query: 661 AIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGF 720
AIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGF
Sbjct: 661 AIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGF 720
Query: 721 PECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALY 780
PECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALY
Sbjct: 721 PECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALY 780
Query: 781 FISRGSIEILRGDVVVAILG 800
FISRGSIEILRGDVVVAILG
Sbjct: 781 FISRGSIEILRGDVVVAILG 800
>gi|26051273 voltage-gated potassium channel, subfamily H, member 2
isoform c [Homo sapiens]
Length = 819
Score = 1598 bits (4138), Expect = 0.0
Identities = 783/784 (99%), Positives = 784/784 (100%)
Query: 376 QVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKE 435
+VLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKE
Sbjct: 36 EVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKE 95
Query: 436 TEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFK 495
TEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFK
Sbjct: 96 TEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFK 155
Query: 496 GWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMC 555
GWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMC
Sbjct: 156 GWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMC 215
Query: 556 TFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTAL 615
TFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTAL
Sbjct: 216 TFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTAL 275
Query: 616 YFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHT 675
YFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHT
Sbjct: 276 YFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHT 335
Query: 676 QMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRS 735
QMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRS
Sbjct: 336 QMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRS 395
Query: 736 LLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVV 795
LLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVV
Sbjct: 396 LLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVV 455
Query: 796 VAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSS 855
VAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSS
Sbjct: 456 VAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSS 515
Query: 856 LEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGA 915
LEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGA
Sbjct: 516 LEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGA 575
Query: 916 GPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLME 975
GPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLME
Sbjct: 576 GPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLME 635
Query: 976 DCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPR 1035
DCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPR
Sbjct: 636 DCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPR 695
Query: 1036 GDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLL 1095
GDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLL
Sbjct: 696 GDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLL 755
Query: 1096 PVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGS 1155
PVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGS
Sbjct: 756 PVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGS 815
Query: 1156 DPGS 1159
DPGS
Sbjct: 816 DPGS 819
>gi|27886653 potassium voltage-gated channel, subfamily H, member 7
isoform 1 [Homo sapiens]
Length = 1196
Score = 1234 bits (3192), Expect = 0.0
Identities = 679/1113 (61%), Positives = 795/1113 (71%), Gaps = 69/1113 (6%)
Query: 1 MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVM 60
MPVRRGHVAPQNTFL TIIRKFEGQ++KFIIANARV+NCA+IYCNDGFCE+ G+SR +VM
Sbjct: 1 MPVRRGHVAPQNTFLGTIIRKFEGQNKKFIIANARVQNCAIIYCNDGFCEMTGFSRPDVM 60
Query: 61 QRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDG 120
Q+PCTCDFLHGP T+R AQIAQALLG+EERKVE+ +Y K+GS F+C ++PVKN++G
Sbjct: 61 QKPCTCDFLHGPETKRHDIAQIAQALLGSEERKVEVTYYHKNGSTFICNTHIIPVKNQEG 120
Query: 121 AVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSV 180
+MFI+NFE V + + +P R P + K F K P L LT R+ S+
Sbjct: 121 VAMMFIINFEYVTDNENAATP-----ERVNPILPIKTVNRKFFGFKFPGLRVLTYRKQSL 175
Query: 181 RSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPG-- 238
P VV+D + S +S+A+ + A++ +AL+ P
Sbjct: 176 PQED------PDVVVID----SSKHSDDSVAMKHFKSPTKESCSPSEADDTKALIQPSKC 225
Query: 239 SPPRSAPGQL----PSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAG 294
SP + G L P + L PD SS L+ +RSRES S+RRASS DIE G
Sbjct: 226 SPLVNISGPLDHSSPKRQWDRLYPDMLQSSSQLSHSRSRESLCSIRRASSVHDIEGF--G 283
Query: 295 VLPPP---PRHAST-------GAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLK 344
V P RHAS G + ++S LL STSDS+L +Y TI+KIPQ+TLNF ++K
Sbjct: 284 VHPKNIFRDRHASEDNGRNVKGPFNHIKSSLLGSTSDSNLNKYSTINKIPQLTLNFSEVK 343
Query: 345 GDPFLASP-TSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHY 403
+ +SP +SD+ IIAPK+K+RTHNVTEKVTQVLSLGADVLPEYKLQ PRI+++TILHY
Sbjct: 344 TEKKNSSPPSSDKTIIAPKVKDRTHNVTEKVTQVLSLGADVLPEYKLQTPRINKFTILHY 403
Query: 404 SPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMF 463
SPFKAVWDWLILLLVIYTA+FTPYSAAFLL + EE ECGY+C PL VVDLIVDIMF
Sbjct: 404 SPFKAVWDWLILLLVIYTAIFTPYSAAFLLNDREE-QKRRECGYSCSPLNVVDLIVDIMF 462
Query: 464 IVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEE---L 520
I+DILINFRTTYVN NEEVVS P +IA+HYFKGWFLIDMVAAIPFDLLIFGSGS+E L
Sbjct: 463 IIDILINFRTTYVNQNEEVVSDPAKIAIHYFKGWFLIDMVAAIPFDLLIFGSGSDETTTL 522
Query: 521 IGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMD 580
IGLLKTARLLRLVRVARKLDRYSEYGAAVL LLMC FALIAHWLACIWYAIGN+E+P++
Sbjct: 523 IGLLKTARLLRLVRVARKLDRYSEYGAAVLMLLMCIFALIAHWLACIWYAIGNVERPYLT 582
Query: 581 SRIGWLHNLGDQIGKPYNSS-GLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKI 639
+IGWL +LG QIGK YN S GPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKI
Sbjct: 583 DKIGWLDSLGQQIGKRYNDSDSSSGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKI 642
Query: 640 FSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEE 699
FSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYH QMLRV+EFIRFHQIPNPLRQRLEE
Sbjct: 643 FSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHMQMLRVKEFIRFHQIPNPLRQRLEE 702
Query: 700 YFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFK 759
YFQHAW+YTNGIDMN VLKGFPECLQADICLHLN++LLQ+CK FRGA+KGCLRALAMKFK
Sbjct: 703 YFQHAWTYTNGIDMNMVLKGFPECLQADICLHLNQTLLQNCKAFRGASKGCLRALAMKFK 762
Query: 760 TTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSN 819
TTHAPPGDTLVH GD+LTALYF+SRGSIEIL+ D+VVAILGKNDIFGE ++LYA+PGKSN
Sbjct: 763 TTHAPPGDTLVHCGDVLTALYFLSRGSIEILKDDIVVAILGKNDIFGEMVHLYAKPGKSN 822
Query: 820 GDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNM---IPGSPGSTE 876
DVRALTYCDLHKI R+DLLEVLDMYPEFSDHF ++LE+TFNLR + + S +
Sbjct: 823 ADVRALTYCDLHKIQREDLLEVLDMYPEFSDHFLTNLELTFNLRHESAKADLLRSQSMND 882
Query: 877 LEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPS 936
EG + R+RKLSF +K+ + R + E S S
Sbjct: 883 SEGDNCKLRRRKLSFESEGEKENSTNDPEDSADTIRHYQSSKRH------FEEKKSRSSS 936
Query: 937 SPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSN 996
S +DE P S P G+ D E++ P SG
Sbjct: 937 FISSIDDEQK----------PLFSGIVDSSPGIGKASGLDFEETV----PTSGRMHIDKR 982
Query: 997 IFSFWGDSRGRQYQELPRCPAP---TPSLLNIPL----SSPGRRPRGDVESRLDALQRQL 1049
S + R ++ P P +PS L + G+VE RLD LQ QL
Sbjct: 983 SHSCKDITDMRSWERENAHPQPEDSSPSALQRAAWGISETESDLTYGEVEQRLDLLQEQL 1042
Query: 1050 NRLETRLSADMATVLQLLQRQMTLVPPAYSAVT 1082
NRLE++++ D+ T+LQLLQ+Q T+VPPAYS VT
Sbjct: 1043 NRLESQMTTDIQTILQLLQKQTTVVPPAYSMVT 1075
>gi|27886665 potassium voltage-gated channel, subfamily H, member 7
isoform 2 [Homo sapiens]
Length = 732
Score = 930 bits (2403), Expect = 0.0
Identities = 490/730 (67%), Positives = 564/730 (77%), Gaps = 32/730 (4%)
Query: 1 MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVM 60
MPVRRGHVAPQNTFL TIIRKFEGQ++KFIIANARV+NCA+IYCNDGFCE+ G+SR +VM
Sbjct: 1 MPVRRGHVAPQNTFLGTIIRKFEGQNKKFIIANARVQNCAIIYCNDGFCEMTGFSRPDVM 60
Query: 61 QRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDG 120
Q+PCTCDFLHGP T+R AQIAQALLG+EERKVE+ +Y K+GS F+C ++PVKN++G
Sbjct: 61 QKPCTCDFLHGPETKRHDIAQIAQALLGSEERKVEVTYYHKNGSTFICNTHIIPVKNQEG 120
Query: 121 AVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSV 180
+MFI+NFE V + + +P R P + K F K P L LT R+ S+
Sbjct: 121 VAMMFIINFEYVTDNENAATP-----ERVNPILPIKTVNRKFFGFKFPGLRVLTYRKQSL 175
Query: 181 RSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPG-- 238
P VV+D + S +S+A+ + A++ +AL+ P
Sbjct: 176 PQED------PDVVVID----SSKHSDDSVAMKHFKSPTKESCSPSEADDTKALIQPSKC 225
Query: 239 SPPRSAPGQL----PSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAG 294
SP + G L P + L PD SS L+ +RSRES S+RRASS DIE G
Sbjct: 226 SPLVNISGPLDHSSPKRQWDRLYPDMLQSSSQLSHSRSRESLCSIRRASSVHDIEGF--G 283
Query: 295 VLPPP---PRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLAS 351
V P RHAS G + ++S LL STSDS+L +Y TI+KIPQ+TLNF ++K + +S
Sbjct: 284 VHPKNIFRDRHASEGPFNHIKSSLLGSTSDSNLNKYSTINKIPQLTLNFSEVKTEKKNSS 343
Query: 352 P-TSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVW 410
P +SD+ IIAPK+K+RTHNVTEKVTQVLSLGADVLPEYKLQ PRI+++TILHYSPFKAVW
Sbjct: 344 PPSSDKTIIAPKVKDRTHNVTEKVTQVLSLGADVLPEYKLQTPRINKFTILHYSPFKAVW 403
Query: 411 DWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILIN 470
DWLILLLVIYTA+FTPYSAAFLL + EE ECGY+C PL VVDLIVDIMFI+DILIN
Sbjct: 404 DWLILLLVIYTAIFTPYSAAFLLNDREE-QKRRECGYSCSPLNVVDLIVDIMFIIDILIN 462
Query: 471 FRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEE---LIGLLKTA 527
FRTTYVN NEEVVS P +IA+HYFKGWFLIDMVAAIPFDLLIFGSGS+E LIGLLKTA
Sbjct: 463 FRTTYVNQNEEVVSDPAKIAIHYFKGWFLIDMVAAIPFDLLIFGSGSDETTTLIGLLKTA 522
Query: 528 RLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLH 587
RLLRLVRVARKLDRYSEYGAAVL LLMC FALIAHWLACIWYAIGN+E+P++ +IGWL
Sbjct: 523 RLLRLVRVARKLDRYSEYGAAVLMLLMCIFALIAHWLACIWYAIGNVERPYLTDKIGWLD 582
Query: 588 NLGDQIGKPYNSS-GLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVML 646
+LG QIGK YN S GPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVML
Sbjct: 583 SLGQQIGKRYNDSDSSSGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVML 642
Query: 647 IGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWS 706
IGSLMYASIFGNVSAIIQRLYSGTARYH QMLRV+EFIRFHQIPNPLRQRLEEYFQHAW+
Sbjct: 643 IGSLMYASIFGNVSAIIQRLYSGTARYHMQMLRVKEFIRFHQIPNPLRQRLEEYFQHAWT 702
Query: 707 YTNGIDMNAV 716
YTNGIDMN V
Sbjct: 703 YTNGIDMNMV 712
>gi|13540549 potassium voltage-gated channel, subfamily H, member 6
isoform 1 [Homo sapiens]
Length = 994
Score = 926 bits (2393), Expect = 0.0
Identities = 532/868 (61%), Positives = 605/868 (69%), Gaps = 89/868 (10%)
Query: 326 RYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAP-KIKERTHNVTEKVTQVLSLGADV 384
+YRTIS+IPQ TLNFV+ + +S T++ EIIAP K+ ERT NVTEKVTQVLSLGADV
Sbjct: 174 KYRTISQIPQFTLNFVEFNLEKHRSSSTTEIEIIAPHKVVERTQNVTEKVTQVLSLGADV 233
Query: 385 LPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATE 444
LPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLL + +E
Sbjct: 234 LPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLSDQDESRRGA- 292
Query: 445 CGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVA 504
C Y C PL VVDLIVDIMF+VDI+INFRTTYVN N+EVVSHP RIAVHYFKGWFLIDMVA
Sbjct: 293 CSYTCSPLTVVDLIVDIMFVVDIVINFRTTYVNTNDEVVSHPRRIAVHYFKGWFLIDMVA 352
Query: 505 AIPFDLLIFGSGSEE---LIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIA 561
AIPFDLLIF +GS+E LIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIA
Sbjct: 353 AIPFDLLIFRTGSDETTTLIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIA 412
Query: 562 HWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSG-LGGPSIKDKYVTALYFTFS 620
HWLACIWYAIGN+E+P+++ +IGWL +LG Q+GK YN S GPS++DKYVTALYFTFS
Sbjct: 413 HWLACIWYAIGNVERPYLEHKIGWLDSLGVQLGKRYNGSDPASGPSVQDKYVTALYFTFS 472
Query: 621 SLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRV 680
SLTSVGFGNVSPNTNSEK+FSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRV
Sbjct: 473 SLTSVGFGNVSPNTNSEKVFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRV 532
Query: 681 REFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHC 740
+EFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHL+R+LLQHC
Sbjct: 533 KEFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLHRALLQHC 592
Query: 741 KPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILG 800
F GA KGCLRALA+KFKTTHAPPGDTLVH GD+L+ LYFISRGSIEILR DVVVAILG
Sbjct: 593 PAFSGAGKGCLRALAVKFKTTHAPPGDTLVHLGDVLSTLYFISRGSIEILRDDVVVAILG 652
Query: 801 KNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITF 860
KNDIFGEP++L+A+PGKS+ DVRALTYCDLHKI R DLLEVLDMYP F++ FWS LE+TF
Sbjct: 653 KNDIFGEPVSLHAQPGKSSADVRALTYCDLHKIQRADLLEVLDMYPAFAESFWSKLEVTF 712
Query: 861 NLRDT-----NMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEV---------S 906
NLRD + +PGS + +G F +D + P E+ S
Sbjct: 713 NLRDAAGGLHSSPRQAPGSQDHQGFF------------LSDNQSGSPHELGPQFPSKGYS 760
Query: 907 ALGPG---RAGAGPSSRGRPGG--PWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSP 961
LGPG GAGP + G P P S +SG PE ++ + P SP
Sbjct: 761 LLGPGSQNSMGAGPCAPGHPDAAPPLSISDASG-LWPELLQE-----------MPPRHSP 808
Query: 962 RPPGEPPGGEPLM--EDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPT 1019
+ P E P PL E+ N L S S++ SR Q + P
Sbjct: 809 QSPQEDPDCWPLKLGSRLEQLQAQMNRLESRVS--SDL------SRILQLLQKPMPQGHA 860
Query: 1020 PSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYS 1079
+L P S+ + L + + RL Q P+Y
Sbjct: 861 SYILEAPASN---------DLALVPIASETTSPGPRLPQGFLPPAQ---------TPSYG 902
Query: 1080 AVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEEL--PPGAPELPQE------G 1131
+ P ++SP +P L T +L+ S+ E L P +P P E G
Sbjct: 903 DLDDCSPKHRNSSPRMP--HLAVATDKTLAPSSEQEQPEGLWPPLASPLHPLEVQGLICG 960
Query: 1132 PTRRLSLPGQLGALTSQ-PLHRHGSDPG 1158
P SLP LG++ Q RHGSDPG
Sbjct: 961 PCFS-SLPEHLGSVPKQLDFQRHGSDPG 987
Score = 224 bits (570), Expect = 5e-58
Identities = 106/130 (81%), Positives = 117/130 (90%)
Query: 1 MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVM 60
MPVRRGHVAPQNT+LDTIIRKFEGQSRKF+IANA++ENCA+IYCNDGFCEL GYSR EVM
Sbjct: 1 MPVRRGHVAPQNTYLDTIIRKFEGQSRKFLIANAQMENCAIIYCNDGFCELFGYSRVEVM 60
Query: 61 QRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDG 120
Q+PCTCDFL GP T A +++AQALLGAEE KV+I +YRKD S F CLVDVVPVKNEDG
Sbjct: 61 QQPCTCDFLTGPNTPSSAVSRLAQALLGAEECKVDILYYRKDASSFRCLVDVVPVKNEDG 120
Query: 121 AVIMFILNFE 130
AVIMFILNFE
Sbjct: 121 AVIMFILNFE 130
>gi|27886651 potassium voltage-gated channel, subfamily H, member 6
isoform 2 [Homo sapiens]
Length = 905
Score = 813 bits (2099), Expect = 0.0
Identities = 422/565 (74%), Positives = 456/565 (80%), Gaps = 62/565 (10%)
Query: 326 RYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAP-KIKERTHNVTEKVTQVLSLGADV 384
+YRTIS+IPQ TLNFV+ + +S T++ EIIAP K+ ERT NVTEKVTQVLSLGADV
Sbjct: 174 KYRTISQIPQFTLNFVEFNLEKHRSSSTTEIEIIAPHKVVERTQNVTEKVTQVLSLGADV 233
Query: 385 LPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATE 444
LPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLL + +E
Sbjct: 234 LPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLSDQDESRRGA- 292
Query: 445 CGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVA 504
C Y C PL VVDLIVDIMF+VDI+INFRTTYVN N+EVVSHP RIAVHYFKGWFLIDMVA
Sbjct: 293 CSYTCSPLTVVDLIVDIMFVVDIVINFRTTYVNTNDEVVSHPRRIAVHYFKGWFLIDMVA 352
Query: 505 AIPFDLLIFGSGSEE---LIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIA 561
AIPFDLLIF +GS+E LIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIA
Sbjct: 353 AIPFDLLIFRTGSDETTTLIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIA 412
Query: 562 HWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSS 621
HWLACI S
Sbjct: 413 HWLACI----------------------------------------------------CS 420
Query: 622 LTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVR 681
LTSVGFGNVSPNTNSEK+FSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRV+
Sbjct: 421 LTSVGFGNVSPNTNSEKVFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVK 480
Query: 682 EFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCK 741
EFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHL+R+LLQHC
Sbjct: 481 EFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLHRALLQHCP 540
Query: 742 PFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGK 801
F GA KGCLRALA+KFKTTHAPPGDTLVH GD+L+ LYFISRGSIEILR DVVVAILGK
Sbjct: 541 AFSGAGKGCLRALAVKFKTTHAPPGDTLVHLGDVLSTLYFISRGSIEILRDDVVVAILGK 600
Query: 802 NDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFN 861
NDIFGEP++L+A+PGKS+ DVRALTYCDLHKI R DLLEVLDMYP F++ FWS LE+TFN
Sbjct: 601 NDIFGEPVSLHAQPGKSSADVRALTYCDLHKIQRADLLEVLDMYPAFAESFWSKLEVTFN 660
Query: 862 LRDT-----NMIPGSPGSTELEGGF 881
LRD + +PGS + +G F
Sbjct: 661 LRDAAGGLHSSPRQAPGSQDHQGFF 685
Score = 224 bits (570), Expect = 5e-58
Identities = 106/130 (81%), Positives = 117/130 (90%)
Query: 1 MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVM 60
MPVRRGHVAPQNT+LDTIIRKFEGQSRKF+IANA++ENCA+IYCNDGFCEL GYSR EVM
Sbjct: 1 MPVRRGHVAPQNTYLDTIIRKFEGQSRKFLIANAQMENCAIIYCNDGFCELFGYSRVEVM 60
Query: 61 QRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDG 120
Q+PCTCDFL GP T A +++AQALLGAEE KV+I +YRKD S F CLVDVVPVKNEDG
Sbjct: 61 QQPCTCDFLTGPNTPSSAVSRLAQALLGAEECKVDILYYRKDASSFRCLVDVVPVKNEDG 120
Query: 121 AVIMFILNFE 130
AVIMFILNFE
Sbjct: 121 AVIMFILNFE 130
Score = 53.9 bits (128), Expect = 9e-07
Identities = 79/250 (31%), Positives = 103/250 (41%), Gaps = 71/250 (28%)
Query: 959 SSPRP-PGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPA 1017
SSPR PG + D SD PLS +S+ W + QE+P +
Sbjct: 670 SSPRQAPGSQDHQGFFLSD--NQSDAAPPLS-----ISDASGLWPEL----LQEMPPRHS 718
Query: 1018 PTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQM------ 1071
P P P P + SRL+ LQ Q+NRLE+R+S+D++ +LQLLQ+ M
Sbjct: 719 PQS-----PQEDPDCWPL-KLGSRLEQLQAQMNRLESRVSSDLSRILQLLQKPMPQGHAS 772
Query: 1072 -----------TLVPPAYSAVTTPGP-------GPTST----------------SPLLPV 1097
LVP A S T+PGP P T SP +P
Sbjct: 773 YILEAPASNDLALVPIA-SETTSPGPRLPQGFLPPAQTPSYGDLDDCSPKHRNSSPRMP- 830
Query: 1098 SPLPTLTLDSLSQVSQFMACEEL--PPGAPELPQE------GPTRRLSLPGQLGALTSQ- 1148
L T +L+ S+ E L P +P P E GP SLP LG++ Q
Sbjct: 831 -HLAVATDKTLAPSSEQEQPEGLWPPLASPLHPLEVQGLICGPCFS-SLPEHLGSVPKQL 888
Query: 1149 PLHRHGSDPG 1158
RHGSDPG
Sbjct: 889 DFQRHGSDPG 898
>gi|6912446 potassium voltage-gated channel, subfamily H, member 4
[Homo sapiens]
Length = 1017
Score = 478 bits (1231), Expect = e-134
Identities = 316/800 (39%), Positives = 437/800 (54%), Gaps = 77/800 (9%)
Query: 385 LPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATE 444
+PEYK+ + R +LHYS KA+WD LILL Y AV PY+ F ++ P T
Sbjct: 204 VPEYKVASVGGSRCLLLHYSVSKAIWDGLILLATFYVAVTVPYNVCF---SGDDDTPITS 260
Query: 445 CGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVA 504
+ V D+ V+++FI+DI++NFRTTYV+ + +V+S P I +HY WF ID++A
Sbjct: 261 -----RHTLVSDIAVEMLFILDIILNFRTTYVSQSGQVISAPRSIGLHYLATWFFIDLIA 315
Query: 505 AIPFDLL-IFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHW 563
A+PFDLL IF L+ LLKT RLLRL+R+ +KL+RYS+ A VL LLM FAL+AHW
Sbjct: 316 ALPFDLLYIFNITVTSLVHLLKTVRLLRLLRLLQKLERYSQCSAVVLTLLMSVFALLAHW 375
Query: 564 LACIWYAIGNMEQPHMDSR---IGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFS 620
+ACIWY IG E D IGWLH LG ++ PY + +GGPS + Y+ ALYFT S
Sbjct: 376 MACIWYVIGRREMEANDPLLWDIGWLHELGKRLEVPYVNGSVGGPSRRSAYIAALYFTLS 435
Query: 621 SLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRV 680
SLTSVGFGNV NT++EKIFSIC MLIG+LM+A +FGNV+AIIQR+YS + YH++M +
Sbjct: 436 SLTSVGFGNVCANTDAEKIFSICTMLIGALMHAVVFGNVTAIIQRMYSRRSLYHSRMKDL 495
Query: 681 REFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHC 740
++FIR H++P PL+QR+ EYFQ W+ +GID N +L+ FP+ L+ADI +HLNR +LQ
Sbjct: 496 KDFIRVHRLPRPLKQRMLEYFQTTWAVNSGIDANELLRDFPDELRADIAMHLNREILQ-L 554
Query: 741 KPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILG 800
F A++GCLRAL++ KT+ PG+ L+ GD L A Y++ GS+E+LR ++V+AILG
Sbjct: 555 PLFGAASRGCLRALSLHIKTSFCAPGEYLLRRGDALQAHYYVCSGSLEVLRDNMVLAILG 614
Query: 801 KNDIFGEPL-------NLYARPG---KSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSD 850
K D+ G + L A P K++ DV+ALTYC L ++ L EVL +YPE+
Sbjct: 615 KGDLIGADIPEPGQEPGLGADPNFVLKTSADVKALTYCGLQQLSSRGLAEVLRLYPEYGA 674
Query: 851 HFWSSL--EITFNLRDTNMIPGSPGSTELEGGFSR-QRKRKLSFRRRTDKDTEQPGEVSA 907
F + L ++TFNLR GS S G SR R +LS R + + +
Sbjct: 675 AFRAGLPRDLTFNLRQ-----GSDTS-----GLSRFSRSPRLSQPRSESLGSSSDKTLPS 724
Query: 908 LGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESS-----EDEGPGRS---SSPLRLVPFS 959
+ +GA P RP P P+ P+ P S +E P S SSP L P
Sbjct: 725 ITEAESGAEPGGGPRPRRPL-LLPNLSPARPRGSLVSLLGEELPPFSALVSSP-SLSPSL 782
Query: 960 SPRPPGE----PPGGEPLMEDCEKSSDTCNPLSGAF----------SGVSNIFSFWGDSR 1005
SP G+ P G P K P G F G+ + S ++
Sbjct: 783 SPALAGQGHSASPHGPPRCSAAWKPPQLLIPPLGTFGPPDLSPRIVDGIEDSGS-TAEAP 841
Query: 1006 GRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQ 1065
++ P P P G RP ++ S + ++ ++ RL +S V Q
Sbjct: 842 SFRFSRRPELPRPRSQ-----APPTGTRPSPELASEAEEVKEKVCRLNQEISRLNQEVSQ 896
Query: 1066 LLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAP 1125
L R++ + A P PG + S P P P L LS C PP P
Sbjct: 897 -LSRELRHIMGLLQARLGP-PGHPAGSAWTPDPPCPQLRPPCLS------PCASRPP--P 946
Query: 1126 ELPQEGPTRRLSLPGQLGAL 1145
L Q+ + P +G +
Sbjct: 947 SL-QDTTLAEVHCPASVGTM 965
Score = 154 bits (389), Expect = 5e-37
Identities = 74/155 (47%), Positives = 104/155 (67%), Gaps = 11/155 (7%)
Query: 1 MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANAR-VENCAVIYCNDGFCELCGYSRAEV 59
MPV +G +APQNTFLDTI +F+G F++ANA+ ++YC+DGFCEL GY R EV
Sbjct: 1 MPVMKGLLAPQNTFLDTIATRFDGTHSNFLLANAQGTRGFPIVYCSDGFCELTGYGRTEV 60
Query: 60 MQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNED 119
MQ+ C+C FL+GP T A ++ +AL G +E + EI FYRKDGS F CL+D++P+KNE
Sbjct: 61 MQKTCSCRFLYGPETSEPALQRLHKALEGHQEHRAEICFYRKDGSAFWCLLDMMPIKNEM 120
Query: 120 GAVIMFILNFEVVMEKDMVGSPA-------HDTNH 147
G V++F+ +F+ + + GSP D+NH
Sbjct: 121 GEVVLFLFSFKDITQS---GSPGLGPQGGRGDSNH 152
>gi|27886667 potassium voltage-gated channel, subfamily H, member 8
[Homo sapiens]
Length = 1107
Score = 477 bits (1228), Expect = e-134
Identities = 291/738 (39%), Positives = 419/738 (56%), Gaps = 52/738 (7%)
Query: 373 KVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFL 432
K+ + + PEYK+ + ++ +LH+S FKA WDWLILL Y AV PY+ F+
Sbjct: 187 KINNNVFVDKPAFPEYKVSDAKKSKFILLHFSTFKAGWDWLILLATFYVAVTVPYNVCFI 246
Query: 433 LKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVH 492
+ +T V D+ V+I+FI+DI++NFRTTYV+ + +V+ I +H
Sbjct: 247 GNDDLSTTRST---------TVSDIAVEILFIIDIILNFRTTYVSKSGQVIFEARSICIH 297
Query: 493 YFKGWFLIDMVAAIPFDLLI-FGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLF 551
Y WF+ID++AA+PFDLL F L+ LLKT RLLRL+R+ +KLDRYS++ VL
Sbjct: 298 YVTTWFIIDLIAALPFDLLYAFNVTVVSLVHLLKTVRLLRLLRLLQKLDRYSQHSTIVLT 357
Query: 552 LLMCTFALIAHWLACIWYAIGNMEQPH---MDSRIGWLHNLGDQIGKPY-NSSGLGGPSI 607
LLM FAL+AHW+ACIWY IG ME+ + +GWLH LG ++ PY ++ LGGPSI
Sbjct: 358 LLMSMFALLAHWMACIWYVIGKMEREDNSLLKWEVGWLHELGKRLESPYYGNNTLGGPSI 417
Query: 608 KDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLY 667
+ Y+ ALYFT SSLTSVGFGNVS NT++EKIFSIC MLIG+LM+A +FGNV+AIIQR+Y
Sbjct: 418 RSAYIAALYFTLSSLTSVGFGNVSANTDAEKIFSICTMLIGALMHALVFGNVTAIIQRMY 477
Query: 668 SGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQAD 727
S + YHT+ +++FIR H +P L+QR+ EYFQ WS NGID N +LK FP+ L++D
Sbjct: 478 SRWSLYHTRTKDLKDFIRVHHLPQQLKQRMLEYFQTTWSVNNGIDSNELLKDFPDELRSD 537
Query: 728 ICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSI 787
I +HLN+ +LQ F A++GCLR+L++ KT+ PG+ L+ GD L A+YF+ GS+
Sbjct: 538 ITMHLNKEILQ-LSLFECASRGCLRSLSLHIKTSFCAPGEYLLRQGDALQAIYFVCSGSM 596
Query: 788 EILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPE 847
E+L+ +V+AILGK D+ G L++ + K+N DV+ALTYCDL I L EVLD+YPE
Sbjct: 597 EVLKDSMVLAILGKGDLIGANLSIKDQVIKTNADVKALTYCDLQCIILKGLFEVLDLYPE 656
Query: 848 FSDHFWSSL--EITFNLRD-------TNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKD 898
++ F + ++T+NLR+ + + S S G KR S +++
Sbjct: 657 YAHKFVEDIQHDLTYNLREGHESDVISRLSNKSMVSQSEPKGNGNINKRLPSIVEDEEEE 716
Query: 899 TEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPF 958
E E + G SSR + G G S + + P SP+R+
Sbjct: 717 EEGEEEEAVSLSPICTRGSSSRNKKVG--SNKAYLGLSLKQLASGTVP--FHSPIRVSRS 772
Query: 959 SSPRPPGE--PPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCP 1016
+SP+ E PP E K + +G I G G +E
Sbjct: 773 NSPKTKQEIDPPNHNKRKEKNLKLQLSTLNNAGPPDLSPRIVD--GIEDGNSSEESQTFD 830
Query: 1017 APTPSLLNIPLSSPGRRPRGDVE-------SRLDALQRQLNRLE----------TRLSAD 1059
+ + + P SP P GD E + + ++Q+N+L ++L D
Sbjct: 831 FGSERIRSEPRISP---PLGDPEIGAAVLFIKAEETKQQINKLNSEVTTLTQEVSQLGKD 887
Query: 1060 MATVLQLLQRQMTLVPPA 1077
M V+QLL+ ++ P+
Sbjct: 888 MRNVIQLLENVLSPQQPS 905
Score = 144 bits (362), Expect = 6e-34
Identities = 68/142 (47%), Positives = 99/142 (69%), Gaps = 1/142 (0%)
Query: 1 MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARV-ENCAVIYCNDGFCELCGYSRAEV 59
MPV +G +APQNTFLDTI +F+G FI+ANA+V + ++YC+DGFCEL G++R EV
Sbjct: 1 MPVMKGLLAPQNTFLDTIATRFDGTHSNFILANAQVAKGFPIVYCSDGFCELAGFARTEV 60
Query: 60 MQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNED 119
MQ+ C+C FL G T + QI ++L E K EI FY+K+GS F CL+D+VP+KNE
Sbjct: 61 MQKSCSCKFLFGVETNEQLMLQIEKSLEEKTEFKGEIMFYKKNGSPFWCLLDIVPIKNEK 120
Query: 120 GAVIMFILNFEVVMEKDMVGSP 141
G V++F+ +F+ + + + +P
Sbjct: 121 GDVVLFLASFKDITDTKVKITP 142
>gi|4504831 potassium voltage-gated channel, subfamily H, member 1
isoform 2 [Homo sapiens]
Length = 962
Score = 471 bits (1213), Expect = e-132
Identities = 243/530 (45%), Positives = 344/530 (64%), Gaps = 32/530 (6%)
Query: 353 TSDREII---APKIK--ERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFK 407
TS R ++ AP ++ E H + ++ +VL LG+D+LP+YK +AP+ ILHY FK
Sbjct: 159 TSSRGVLQQLAPSVQKGENVHKHS-RLAEVLQLGSDILPQYKQEAPKTPPHIILHYCVFK 217
Query: 408 AVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDI 467
WDW+IL+L YTA+ PY+ +F ++ VVD IVD++F+VDI
Sbjct: 218 TTWDWIILILTFYTAILVPYNVSFKTRQNNVA------------WLVVDSIVDVIFLVDI 265
Query: 468 LINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLI----FGSGSEELIGL 523
++NF TT+V EV+S P I ++Y K WF+ID+++ +P+D++ G L
Sbjct: 266 VLNFHTTFVGPAGEVISDPKLIRMNYLKTWFVIDLLSCLPYDVINAFENVDEGISSLFSS 325
Query: 524 LKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRI 583
LK RLLRL RVARKLD Y EYGAAVL LL+C F L AHW+ACIWY+IG+ E D++
Sbjct: 326 LKVVRLLRLGRVARKLDHYIEYGAAVLVLLVCVFGLAAHWMACIWYSIGDYEIFDEDTKT 385
Query: 584 ----GWLHNLGDQIGKPYNSSGLG------GPSIKDKYVTALYFTFSSLTSVGFGNVSPN 633
WL+ L IG PY +G G GPS Y+++LYFT +SLTSVGFGN++P+
Sbjct: 386 IRNNSWLYQLAMDIGTPYQFNGSGSGKWEGGPSKNSVYISSLYFTMTSLTSVGFGNIAPS 445
Query: 634 TNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPL 693
T+ EKIF++ +M+IGSL+YA+IFGNV+ I Q++Y+ T RYH + VR+F++ +Q+P L
Sbjct: 446 TDIEKIFAVAIMMIGSLLYATIFGNVTTIFQQMYANTNRYHEMLNSVRDFLKLYQVPKGL 505
Query: 694 RQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRA 753
+R+ +Y WS + GID VL+ P+ ++ADIC+HLNR + + FR A+ GCLRA
Sbjct: 506 SERVMDYIVSTWSMSRGIDTEKVLQICPKDMRADICVHLNRKVFKEHPAFRLASDGCLRA 565
Query: 754 LAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYA 813
LAM+F+T H PGD + HAG+ + +L F+ GS+E+++ D VVAILGK D+FG+ A
Sbjct: 566 LAMEFQTVHCAPGDLIYHAGESVDSLCFVVSGSLEVIQDDEVVAILGKGDVFGDVFWKEA 625
Query: 814 RPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLR 863
+S +VRALTYCDLH I RD L +VL+ Y FS F +L +T+NLR
Sbjct: 626 TLAQSCANVRALTYCDLHVIKRDALQKVLEFYTAFSHSFSRNLILTYNLR 675
Score = 106 bits (264), Expect = 1e-22
Identities = 49/126 (38%), Positives = 75/126 (59%), Gaps = 2/126 (1%)
Query: 4 RRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRP 63
RRG VAPQNTFL+ I+R+ F++ NA++ + ++Y NDGFC+L GY RAEVMQ+
Sbjct: 7 RRGLVAPQNTFLENIVRR--SNDTNFVLGNAQIVDWPIVYSNDGFCKLSGYHRAEVMQKS 64
Query: 64 CTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVI 123
TC F++G T + ++ Q E EI Y+K+ + V + P++NE V+
Sbjct: 65 STCSFMYGELTDKDTIEKVRQTFENYEMNSFEILMYKKNRTPVWFFVKIAPIRNEQDKVV 124
Query: 124 MFILNF 129
+F+ F
Sbjct: 125 LFLCTF 130
>gi|22024390 potassium voltage-gated channel, subfamily H, member 5
isoform 1 [Homo sapiens]
Length = 988
Score = 463 bits (1191), Expect = e-130
Identities = 237/528 (44%), Positives = 339/528 (64%), Gaps = 25/528 (4%)
Query: 349 LASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKA 408
L + S + + P K + ++ +VL LG+D+LP+YK +AP+ ILHY FK
Sbjct: 156 LTNSRSVLQQLTPMNKTEVVHKHSRLAEVLQLGSDILPQYKQEAPKTPPHIILHYCAFKT 215
Query: 409 VWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDIL 468
WDW+IL+L YTA+ PY+ +F K+ V+D +VD++F+VDI+
Sbjct: 216 TWDWVILILTFYTAIMVPYNVSFKTKQNNIA------------WLVLDSVVDVIFLVDIV 263
Query: 469 INFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLI----FGSGSEELIGLL 524
+NF TT+V EV+S P I ++Y K WF+ID+++ +P+D++ G L L
Sbjct: 264 LNFHTTFVGPGGEVISDPKLIRMNYLKTWFVIDLLSCLPYDIINAFENVDEGISSLFSSL 323
Query: 525 KTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQ-PHMDSRI 583
K RLLRL RVARKLD Y EYGAAVL LL+C F L+AHWLACIWY+IG+ E + + I
Sbjct: 324 KVVRLLRLGRVARKLDHYLEYGAAVLVLLVCVFGLVAHWLACIWYSIGDYEVIDEVTNTI 383
Query: 584 ---GWLHNLGDQIGKPYN---SSGL--GGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTN 635
WL+ L IG PY S+G+ GGPS YV++LYFT +SLT++GFGN++P T+
Sbjct: 384 QIDSWLYQLALSIGTPYRYNTSAGIWEGGPSKDSLYVSSLYFTMTSLTTIGFGNIAPTTD 443
Query: 636 SEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQ 695
EK+FS+ +M++GSL+YA+IFGNV+ I Q++Y+ T RYH + VR+F++ +Q+P L +
Sbjct: 444 VEKMFSVAMMMVGSLLYATIFGNVTTIFQQMYANTNRYHEMLNNVRDFLKLYQVPKGLSE 503
Query: 696 RLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALA 755
R+ +Y WS + GID VL P+ ++ADIC+HLNR + FR A+ GCLRALA
Sbjct: 504 RVMDYIVSTWSMSKGIDTEKVLSICPKDMRADICVHLNRKVFNEHPAFRLASDGCLRALA 563
Query: 756 MKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARP 815
++F+T H PGD + HAG+ + AL F+ GS+E+++ D VVAILGK D+FG+
Sbjct: 564 VEFQTIHCAPGDLIYHAGESVDALCFVVSGSLEVIQDDEVVAILGKGDVFGDIFWKETTL 623
Query: 816 GKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLR 863
+ +VRALTYCDLH I R+ LL+VLD Y F++ F +L +T NLR
Sbjct: 624 AHACANVRALTYCDLHIIKREALLKVLDFYTAFANSFSRNLTLTCNLR 671
Score = 103 bits (258), Expect = 7e-22
Identities = 50/146 (34%), Positives = 85/146 (58%), Gaps = 5/146 (3%)
Query: 4 RRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRP 63
+RG VAPQNTFL+ I+R+ S F++ NA++ + V+Y NDGFC+L GY RA+VMQ+
Sbjct: 5 KRGLVAPQNTFLENIVRRSSESS--FLLGNAQIVDWPVVYSNDGFCKLSGYHRADVMQKS 62
Query: 64 CTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVI 123
TC F++G T ++ ++ Q E E+ Y+K+ + + + P++NE V+
Sbjct: 63 STCSFMYGELTDKKTIEKVRQTFDNYESNCFEVLLYKKNRTPVWFYMQIAPIRNEHEKVV 122
Query: 124 MFILNFEVVMEKDMVGSPAHDTNHRG 149
+F+ F+ + + P D + +G
Sbjct: 123 LFLCTFKDI---TLFKQPIEDDSTKG 145
>gi|27886648 potassium voltage-gated channel, subfamily H, member 5
isoform 2 [Homo sapiens]
Length = 624
Score = 463 bits (1191), Expect = e-130
Identities = 237/528 (44%), Positives = 339/528 (64%), Gaps = 25/528 (4%)
Query: 349 LASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKA 408
L + S + + P K + ++ +VL LG+D+LP+YK +AP+ ILHY FK
Sbjct: 98 LTNSRSVLQQLTPMNKTEVVHKHSRLAEVLQLGSDILPQYKQEAPKTPPHIILHYCAFKT 157
Query: 409 VWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDIL 468
WDW+IL+L YTA+ PY+ +F K+ V+D +VD++F+VDI+
Sbjct: 158 TWDWVILILTFYTAIMVPYNVSFKTKQNNIA------------WLVLDSVVDVIFLVDIV 205
Query: 469 INFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLI----FGSGSEELIGLL 524
+NF TT+V EV+S P I ++Y K WF+ID+++ +P+D++ G L L
Sbjct: 206 LNFHTTFVGPGGEVISDPKLIRMNYLKTWFVIDLLSCLPYDIINAFENVDEGISSLFSSL 265
Query: 525 KTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQ-PHMDSRI 583
K RLLRL RVARKLD Y EYGAAVL LL+C F L+AHWLACIWY+IG+ E + + I
Sbjct: 266 KVVRLLRLGRVARKLDHYLEYGAAVLVLLVCVFGLVAHWLACIWYSIGDYEVIDEVTNTI 325
Query: 584 ---GWLHNLGDQIGKPYN---SSGL--GGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTN 635
WL+ L IG PY S+G+ GGPS YV++LYFT +SLT++GFGN++P T+
Sbjct: 326 QIDSWLYQLALSIGTPYRYNTSAGIWEGGPSKDSLYVSSLYFTMTSLTTIGFGNIAPTTD 385
Query: 636 SEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQ 695
EK+FS+ +M++GSL+YA+IFGNV+ I Q++Y+ T RYH + VR+F++ +Q+P L +
Sbjct: 386 VEKMFSVAMMMVGSLLYATIFGNVTTIFQQMYANTNRYHEMLNNVRDFLKLYQVPKGLSE 445
Query: 696 RLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALA 755
R+ +Y WS + GID VL P+ ++ADIC+HLNR + FR A+ GCLRALA
Sbjct: 446 RVMDYIVSTWSMSKGIDTEKVLSICPKDMRADICVHLNRKVFNEHPAFRLASDGCLRALA 505
Query: 756 MKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARP 815
++F+T H PGD + HAG+ + AL F+ GS+E+++ D VVAILGK D+FG+
Sbjct: 506 VEFQTIHCAPGDLIYHAGESVDALCFVVSGSLEVIQDDEVVAILGKGDVFGDIFWKETTL 565
Query: 816 GKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLR 863
+ +VRALTYCDLH I R+ LL+VLD Y F++ F +L +T NLR
Sbjct: 566 AHACANVRALTYCDLHIIKREALLKVLDFYTAFANSFSRNLTLTCNLR 613
Score = 45.8 bits (107), Expect = 2e-04
Identities = 21/90 (23%), Positives = 44/90 (48%), Gaps = 3/90 (3%)
Query: 60 MQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNED 119
MQ+ TC F++G T ++ ++ Q E E+ Y+K+ + + + P++NE
Sbjct: 1 MQKSSTCSFMYGELTDKKTIEKVRQTFDNYESNCFEVLLYKKNRTPVWFYMQIAPIRNEH 60
Query: 120 GAVIMFILNFEVVMEKDMVGSPAHDTNHRG 149
V++F+ F+ + + P D + +G
Sbjct: 61 EKVVLFLCTFKDI---TLFKQPIEDDSTKG 87
>gi|27437001 potassium voltage-gated channel, subfamily H, member 1
isoform 1 [Homo sapiens]
Length = 989
Score = 461 bits (1186), Expect = e-129
Identities = 243/557 (43%), Positives = 344/557 (61%), Gaps = 59/557 (10%)
Query: 353 TSDREII---APKIK--ERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFK 407
TS R ++ AP ++ E H + ++ +VL LG+D+LP+YK +AP+ ILHY FK
Sbjct: 159 TSSRGVLQQLAPSVQKGENVHKHS-RLAEVLQLGSDILPQYKQEAPKTPPHIILHYCVFK 217
Query: 408 AVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDI 467
WDW+IL+L YTA+ PY+ +F ++ VVD IVD++F+VDI
Sbjct: 218 TTWDWIILILTFYTAILVPYNVSFKTRQNNVA------------WLVVDSIVDVIFLVDI 265
Query: 468 LINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIF-------------- 513
++NF TT+V EV+S P I ++Y K WF+ID+++ +P+D++
Sbjct: 266 VLNFHTTFVGPAGEVISDPKLIRMNYLKTWFVIDLLSCLPYDVINAFENVDEVSAFMGDP 325
Query: 514 -----------------GSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCT 556
G L LK RLLRL RVARKLD Y EYGAAVL LL+C
Sbjct: 326 GKIGFADQIPPPLEGRESQGISSLFSSLKVVRLLRLGRVARKLDHYIEYGAAVLVLLVCV 385
Query: 557 FALIAHWLACIWYAIGNMEQPHMDSRI----GWLHNLGDQIGKPYNSSGLG------GPS 606
F L AHW+ACIWY+IG+ E D++ WL+ L IG PY +G G GPS
Sbjct: 386 FGLAAHWMACIWYSIGDYEIFDEDTKTIRNNSWLYQLAMDIGTPYQFNGSGSGKWEGGPS 445
Query: 607 IKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRL 666
Y+++LYFT +SLTSVGFGN++P+T+ EKIF++ +M+IGSL+YA+IFGNV+ I Q++
Sbjct: 446 KNSVYISSLYFTMTSLTSVGFGNIAPSTDIEKIFAVAIMMIGSLLYATIFGNVTTIFQQM 505
Query: 667 YSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQA 726
Y+ T RYH + VR+F++ +Q+P L +R+ +Y WS + GID VL+ P+ ++A
Sbjct: 506 YANTNRYHEMLNSVRDFLKLYQVPKGLSERVMDYIVSTWSMSRGIDTEKVLQICPKDMRA 565
Query: 727 DICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGS 786
DIC+HLNR + + FR A+ GCLRALAM+F+T H PGD + HAG+ + +L F+ GS
Sbjct: 566 DICVHLNRKVFKEHPAFRLASDGCLRALAMEFQTVHCAPGDLIYHAGESVDSLCFVVSGS 625
Query: 787 IEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYP 846
+E+++ D VVAILGK D+FG+ A +S +VRALTYCDLH I RD L +VL+ Y
Sbjct: 626 LEVIQDDEVVAILGKGDVFGDVFWKEATLAQSCANVRALTYCDLHVIKRDALQKVLEFYT 685
Query: 847 EFSDHFWSSLEITFNLR 863
FS F +L +T+NLR
Sbjct: 686 AFSHSFSRNLILTYNLR 702
Score = 106 bits (264), Expect = 1e-22
Identities = 49/126 (38%), Positives = 75/126 (59%), Gaps = 2/126 (1%)
Query: 4 RRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRP 63
RRG VAPQNTFL+ I+R+ F++ NA++ + ++Y NDGFC+L GY RAEVMQ+
Sbjct: 7 RRGLVAPQNTFLENIVRR--SNDTNFVLGNAQIVDWPIVYSNDGFCKLSGYHRAEVMQKS 64
Query: 64 CTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVI 123
TC F++G T + ++ Q E EI Y+K+ + V + P++NE V+
Sbjct: 65 STCSFMYGELTDKDTIEKVRQTFENYEMNSFEILMYKKNRTPVWFFVKIAPIRNEQDKVV 124
Query: 124 MFILNF 129
+F+ F
Sbjct: 125 LFLCTF 130
>gi|38569493 potassium voltage-gated channel, subfamily H
(eag-related), member 3 [Homo sapiens]
Length = 1083
Score = 448 bits (1153), Expect = e-125
Identities = 300/782 (38%), Positives = 408/782 (52%), Gaps = 119/782 (15%)
Query: 385 LPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATE 444
LPEYK+ A R + +LH +A WD ILL +Y AV PYS A E
Sbjct: 202 LPEYKVAAIRKSPFILLHCGALRATWDGFILLATLYVAVTVPYSVCV--------STARE 253
Query: 445 CGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVA 504
A P +V DL V+++FI+DI++NFRTT+V+ + +VV P I +HY WFL+D++A
Sbjct: 254 PSAARGPPSVCDLAVEVLFILDIVLNFRTTFVSKSGQVVFAPKSICLHYVTTWFLLDVIA 313
Query: 505 AIPFDLL-------IFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTF 557
A+PFDLL FG+ LLKT RLLRL+R+ +LDRYS+Y A VL LLM F
Sbjct: 314 ALPFDLLHAFKVNVYFGAH------LLKTVRLLRLLRLLPRLDRYSQYSAVVLTLLMAVF 367
Query: 558 ALIAHWLACIWYAIGNMEQPHMDSR---IGWLHNLGDQIGKPY----------NSSG--- 601
AL+AHW+AC+W+ IG E +S IGWL L ++ PY NSSG
Sbjct: 368 ALLAHWVACVWFYIGQREIESSESELPEIGWLQELARRLETPYYLVGRRPAGGNSSGQSD 427
Query: 602 ---------------LGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVML 646
LGGPS++ Y+T+LYF SSLTSVGFGNVS NT++EKIFSIC ML
Sbjct: 428 NCSSSSEANGTGLELLGGPSLRSAYITSLYFALSSLTSVGFGNVSANTDTEKIFSICTML 487
Query: 647 IGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWS 706
IG+LM+A +FGNV+AIIQR+Y+ YH++ +R++IR H+IP PL+QR+ EYFQ W+
Sbjct: 488 IGALMHAVVFGNVTAIIQRMYARRFLYHSRTRDLRDYIRIHRIPKPLKQRMLEYFQATWA 547
Query: 707 YTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPG 766
NGID +L+ P+ L+ADI +HL++ +LQ F A++GCLRAL++ + PG
Sbjct: 548 VNNGIDTTELLQSLPDELRADIAMHLHKEVLQ-LPLFEAASRGCLRALSLALRPAFCTPG 606
Query: 767 DTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALT 826
+ L+H GD L ALYF+ GS+E+L+G V+AILGK D+ G L + K+N DV+ LT
Sbjct: 607 EYLIHQGDALQALYFVCSGSMEVLKGGTVLAILGKGDLIGCELPRREQVVKANADVKGLT 666
Query: 827 YCDLHKIHRDDLLEVLDMYPEFSDHFWSSL--EITFNLRDTNMIPGSPGSTELEGGFSRQ 884
YC L + L + L +YPEF+ F L E+++NL GS E++
Sbjct: 667 YCVLQCLQLAGLHDSLALYPEFAPRFSRGLRGELSYNL------GAGGGSAEVDTSSLSG 720
Query: 885 RKRKLSFRRRTDKDTEQ------------------PGEVSA------LGPGRAGAGP--S 918
+S + D EQ PG S+ L P R P
Sbjct: 721 DNTLMSTLEEKETDGEQGPTVSPAPADEPSSPLLSPGCTSSSSAAKLLSPRRTAPRPRLG 780
Query: 919 SRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCE 978
RGRPG +GPS+P R+ LRL P PP P +++ E
Sbjct: 781 GRGRPGRAGALKAEAGPSAPP--------RALEGLRLPPMPWNVPPDLSP---RVVDGIE 829
Query: 979 KSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDV 1038
+ P FSF G + P P P LL +P P D
Sbjct: 830 DGCGSDQPK----------FSFRVGQSGPECSSSP-SPGPESGLLTVP-HGPSEARNTDT 877
Query: 1039 ESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTP-----GPGPTSTSP 1093
LD L++ + L ++ M LQ L++ + LV + P GP P STS
Sbjct: 878 ---LDKLRQAVTELSEQV-LQMREGLQSLRQAVQLVLAPHREGPCPRASGEGPCPASTSG 933
Query: 1094 LL 1095
LL
Sbjct: 934 LL 935
Score = 146 bits (369), Expect = 1e-34
Identities = 74/159 (46%), Positives = 98/159 (61%), Gaps = 11/159 (6%)
Query: 1 MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENC-AVIYCNDGFCELCGYSRAEV 59
MP RG +APQNTFLDTI +F+G F++ NA+V V+YC+DGFC+L G+SRAEV
Sbjct: 1 MPAMRGLLAPQNTFLDTIATRFDGTHSNFVLGNAQVAGLFPVVYCSDGFCDLTGFSRAEV 60
Query: 60 MQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNED 119
MQR C C FL+GP T QI +AL +E K E+ YRK G F CL+DV+P+KNE
Sbjct: 61 MQRGCACSFLYGPDTSELVRQQIRKALDEHKEFKAELILYRKSGLPFWCLLDVIPIKNEK 120
Query: 120 GAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPG 158
G V +F+++ + + E T +RG P W G
Sbjct: 121 GEVALFLVSHKDISE----------TKNRGGPDRWKETG 149
>gi|27886646 potassium voltage-gated channel, subfamily H, member 5
isoform 3 [Homo sapiens]
Length = 611
Score = 409 bits (1052), Expect = e-114
Identities = 207/464 (44%), Positives = 299/464 (64%), Gaps = 25/464 (5%)
Query: 349 LASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKA 408
L + S + + P K + ++ +VL LG+D+LP+YK +AP+ ILHY FK
Sbjct: 156 LTNSRSVLQQLTPMNKTEVVHKHSRLAEVLQLGSDILPQYKQEAPKTPPHIILHYCAFKT 215
Query: 409 VWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDIL 468
WDW+IL+L YTA+ PY+ +F K+ V+D +VD++F+VDI+
Sbjct: 216 TWDWVILILTFYTAIMVPYNVSFKTKQNNIA------------WLVLDSVVDVIFLVDIV 263
Query: 469 INFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLI----FGSGSEELIGLL 524
+NF TT+V EV+S P I ++Y K WF+ID+++ +P+D++ G L L
Sbjct: 264 LNFHTTFVGPGGEVISDPKLIRMNYLKTWFVIDLLSCLPYDIINAFENVDEGISSLFSSL 323
Query: 525 KTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQ-PHMDSRI 583
K RLLRL RVARKLD Y EYGAAVL LL+C F L+AHWLACIWY+IG+ E + + I
Sbjct: 324 KVVRLLRLGRVARKLDHYLEYGAAVLVLLVCVFGLVAHWLACIWYSIGDYEVIDEVTNTI 383
Query: 584 ---GWLHNLGDQIGKPYN---SSGL--GGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTN 635
WL+ L IG PY S+G+ GGPS YV++LYFT +SLT++GFGN++P T+
Sbjct: 384 QIDSWLYQLALSIGTPYRYNTSAGIWEGGPSKDSLYVSSLYFTMTSLTTIGFGNIAPTTD 443
Query: 636 SEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQ 695
EK+FS+ +M++GSL+YA+IFGNV+ I Q++Y+ T RYH + VR+F++ +Q+P L +
Sbjct: 444 VEKMFSVAMMMVGSLLYATIFGNVTTIFQQMYANTNRYHEMLNNVRDFLKLYQVPKGLSE 503
Query: 696 RLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALA 755
R+ +Y WS + GID VL P+ ++ADIC+HLNR + FR A+ GCLRALA
Sbjct: 504 RVMDYIVSTWSMSKGIDTEKVLSICPKDMRADICVHLNRKVFNEHPAFRLASDGCLRALA 563
Query: 756 MKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAIL 799
++F+T H PGD + HAG+ + AL F+ GS+E+++ D VVAIL
Sbjct: 564 VEFQTIHCAPGDLIYHAGESVDALCFVVSGSLEVIQDDEVVAIL 607
Score = 103 bits (258), Expect = 7e-22
Identities = 50/146 (34%), Positives = 85/146 (58%), Gaps = 5/146 (3%)
Query: 4 RRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRP 63
+RG VAPQNTFL+ I+R+ S F++ NA++ + V+Y NDGFC+L GY RA+VMQ+
Sbjct: 5 KRGLVAPQNTFLENIVRRSSESS--FLLGNAQIVDWPVVYSNDGFCKLSGYHRADVMQKS 62
Query: 64 CTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVI 123
TC F++G T ++ ++ Q E E+ Y+K+ + + + P++NE V+
Sbjct: 63 STCSFMYGELTDKKTIEKVRQTFDNYESNCFEVLLYKKNRTPVWFYMQIAPIRNEHEKVV 122
Query: 124 MFILNFEVVMEKDMVGSPAHDTNHRG 149
+F+ F+ + + P D + +G
Sbjct: 123 LFLCTFKDI---TLFKQPIEDDSTKG 145
>gi|116325989 hyperpolarization activated cyclic nucleotide-gated
potassium channel 1 [Homo sapiens]
Length = 890
Score = 175 bits (443), Expect = 3e-43
Identities = 176/783 (22%), Positives = 318/783 (40%), Gaps = 107/783 (13%)
Query: 398 WTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDL 457
W I YS F+ WD ++L++++ V P F ++T P + ++
Sbjct: 133 WIIHPYSDFRFYWDLIMLIMMVGNLVIIPVGITFFTEQTTT------------PWIIFNV 180
Query: 458 IVDIMFIVDILINFRTTYVNANE-EVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIF--- 513
D +F++D+++NFRT VN + E++ P I ++Y K WF++D +++IP D +
Sbjct: 181 ASDTVFLLDLIMNFRTGTVNEDSSEIILDPKVIKMNYLKSWFVVDFISSIPVDYIFLIVE 240
Query: 514 -GSGSE--------------ELIGLLKTARLLRLVRVARKLDR-----YSEYGAAV-LFL 552
G SE +++ LL+ RL RL+R + + Y A V +F
Sbjct: 241 KGMDSEVYKTARALRIVRFTKILSLLRLLRLSRLIRYIHQWEEIFHMTYDLASAVVRIFN 300
Query: 553 LMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYV 612
L+ L+ HW C+ + + ++ D + + D GK Y+
Sbjct: 301 LIGMMLLLCHWDGCLQFLVPLLQDFPPDCWVSLNEMVNDSWGKQYSY------------- 347
Query: 613 TALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTAR 672
AL+ S + +G+G +P + S+ ++ M++G+ YA G+ +A+IQ L S +
Sbjct: 348 -ALFKAMSHMLCIGYGAQAPVSMSDLWITMLSMIVGATCYAMFVGHATALIQSLDSSRRQ 406
Query: 673 YHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHL 732
Y + +V +++ FH++P +RQ++ +Y++H + D +L + L+ +I
Sbjct: 407 YQEKYKQVEQYMSFHKLPADMRQKIHDYYEHRYQ-GKIFDEENILNELNDPLREEIVNFN 465
Query: 733 NRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRG 792
R L+ F A + A+ K + PGD ++ G + +YFI G ++
Sbjct: 466 CRKLVATMPLFANADPNFVTAMLSKLRFEVFQPGDYIIREGAVGKKMYFIQHGVAGVITK 525
Query: 793 DVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHF 852
L FGE L G+ VRA TYC L+ + D+ EVL+ YP F
Sbjct: 526 SSKEMKLTDGSYFGEICLL--TKGRRTASVRADTYCRLYSLSVDNFNEVLEEYPMMRRAF 583
Query: 853 WS-SLEITFNLRDTNMIPGSPGSTELEGG-FSRQRKRKLSFRRRTDKDTEQP------GE 904
+ +++ + N I +L G F+ Q L + D++ Q +
Sbjct: 584 ETVAIDRLDRIGKKNSILLQKFQKDLNTGVFNNQENEILKQIVKHDREMVQAIAPINYPQ 643
Query: 905 VSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPP 964
++ L + P+SR R P P +++ L SP P
Sbjct: 644 MTTLNSTSSTTTPTSRMRTQSP-------------------PVYTATSLSHSNLHSPSPS 684
Query: 965 GEPPGGEPLMEDCEKSSDTCNP------LSGAF---SGVSNIFSFWGDSRGRQYQE---- 1011
+ P ++ C ++ C+P + F S ++ S +Q Q+
Sbjct: 685 TQTPQPSAILSPCSYTTAVCSPPVQSPLAARTFHYASPTASQLSLMQQQPQQQVQQSQPP 744
Query: 1012 --LPRCPAPTPSLLNIPLSSPG-RRPRGDVESRLDALQR-QLNRLETRLSADMATVLQLL 1067
P+ P+P P +PG P+ +V AL L R LSA ++ +
Sbjct: 745 QTQPQQPSPQP-------QTPGSSTPKNEVHKSTQALHNTNLTREVRPLSASQPSLPHEV 797
Query: 1068 QRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPP--GAP 1125
++ P P P + P + T+ + + M+ +PP G P
Sbjct: 798 STLISRPHPTVGESLASIPQPVTAVPGTGLQAGGRSTVPQRVTLFRQMSSGAIPPNRGVP 857
Query: 1126 ELP 1128
P
Sbjct: 858 PAP 860
>gi|4885407 hyperpolarization activated cyclic nucleotide-gated
potassium channel 4 [Homo sapiens]
Length = 1203
Score = 174 bits (442), Expect = 3e-43
Identities = 124/474 (26%), Positives = 214/474 (45%), Gaps = 54/474 (11%)
Query: 398 WTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDL 457
W I YS F+ WD +LLL++ + P F E P V ++
Sbjct: 253 WIIHPYSDFRFYWDLTMLLLMVGNLIIIPVGITFFKDENTT------------PWIVFNV 300
Query: 458 IVDIMFIVDILINFRT-TYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSG 516
+ D F++D+++NFRT V N E++ P RI + Y K WF++D +++IP D +
Sbjct: 301 VSDTFFLIDLVLNFRTGIVVEDNTEIILDPQRIKMKYLKSWFMVDFISSIPVDYIFLIVE 360
Query: 517 SEELIGLLKTARLLRLVRVAR--------KLDRYSEY--------------GAAVLFL-- 552
+ + KTAR LR+VR + +L R Y +AV+ +
Sbjct: 361 TRIDSEVYKTARALRIVRFTKILSLLRLLRLSRLIRYIHQWEEIFHMTYDLASAVVRIVN 420
Query: 553 LMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYV 612
L+ L+ HW C+ + + ++ D + + + + GK Y+
Sbjct: 421 LIGMMLLLCHWDGCLQFLVPMLQDFPDDCWVSINNMVNNSWGKQYSY------------- 467
Query: 613 TALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTAR 672
AL+ S + +G+G +P S+ ++ M++G+ YA G+ +A+IQ L S +
Sbjct: 468 -ALFKAMSHMLCIGYGRQAPVGMSDVWLTMLSMIVGATCYAMFIGHATALIQSLDSSRRQ 526
Query: 673 YHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHL 732
Y + +V +++ FH++P RQR+ +Y++H + D ++L E L+ +I
Sbjct: 527 YQEKYKQVEQYMSFHKLPPDTRQRIHDYYEHRYQ-GKMFDEESILGELSEPLREEIINFN 585
Query: 733 NRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRG 792
R L+ F A + ++ K + PGD ++ G + +YFI G + +L
Sbjct: 586 CRKLVASMPLFANADPNFVTSMLTKLRFEVFQPGDYIIREGTIGKKMYFIQHGVVSVLTK 645
Query: 793 DVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYP 846
L FGE + L R G+ VRA TYC L+ + D+ EVL+ YP
Sbjct: 646 GNKETKLADGSYFGE-ICLLTR-GRRTASVRADTYCRLYSLSVDNFNEVLEEYP 697
Score = 35.0 bits (79), Expect = 0.41
Identities = 30/102 (29%), Positives = 46/102 (45%), Gaps = 22/102 (21%)
Query: 903 GEVSALGPGRAGAGPSSRGRPGGPWGESP------SSGPSSPE--------SSEDEGPGR 948
G +++LG G+G + G G +S + G +SP ++E E PG
Sbjct: 98 GSLASLGSRGGGSGGTGSGSSHGHLHDSAEERRLIAEGDASPGEDRTPPGLAAEPERPGA 157
Query: 949 SSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSS-DTCNPLSG 989
S+ P +SP PP +PP +P CE+ S DT + G
Sbjct: 158 SAQPA-----ASPPPPQQPP--QPASASCEQPSVDTAIKVEG 192
>gi|156071470 hyperpolarization activated cyclic nucleotide-gated
potassium channel 2 [Homo sapiens]
Length = 889
Score = 173 bits (438), Expect = 1e-42
Identities = 161/659 (24%), Positives = 271/659 (41%), Gaps = 103/659 (15%)
Query: 398 WTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDL 457
W I YS F+ WD+ +LL ++ + P F ET P V ++
Sbjct: 202 WIIHPYSDFRFYWDFTMLLFMVGNLIIIPVGITFFKDETTA------------PWIVFNV 249
Query: 458 IVDIMFIVDILINFRTTYV-NANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIF--- 513
+ D F++D+++NFRT V N E++ P +I Y + WF++D V++IP D +
Sbjct: 250 VSDTFFLMDLVLNFRTGIVIEDNTEIILDPEKIKKKYLRTWFVVDFVSSIPVDYIFLIVE 309
Query: 514 -GSGSE-----------ELIGLLKTARLLRLVRVARKLDRYSE-----YGAAVLFLLMCT 556
G SE +L RLLRL R+ R + ++ E Y A + +C
Sbjct: 310 KGIDSEVYKTARALRIVRFTKILSLLRLLRLSRLIRYIHQWEEIFHMTYDLASAVMRICN 369
Query: 557 FA----LIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYV 612
L+ HW C+ + + ++ R W+ + +G+ S + Y
Sbjct: 370 LISMMLLLCHWDGCLQFLVPMLQD---FPRNCWV-----------SINGMVNHSWSELYS 415
Query: 613 TALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTAR 672
AL+ S + +G+G +P + ++ ++ M++G+ YA G+ +A+IQ L S +
Sbjct: 416 FALFKAMSHMLCIGYGRQAPESMTDIWLTMLSMIVGATCYAMFIGHATALIQSLDSSRRQ 475
Query: 673 YHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHL 732
Y + +V +++ FH++P RQ++ +Y++H + D +++L L+ +I
Sbjct: 476 YQEKYKQVEQYMSFHKLPADFRQKIHDYYEHRYQ-GKMFDEDSILGELNGPLREEIVNFN 534
Query: 733 NRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRG 792
R L+ F A + A+ K K PGD ++ G + +YFI G + +L
Sbjct: 535 CRKLVASMPLFANADPNFVTAMLTKLKFEVFQPGDYIIREGTIGKKMYFIQHGVVSVLTK 594
Query: 793 DVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHF 852
L FGE + L R G+ VRA TYC L+ + D+ EVL+ YP F
Sbjct: 595 GNKEMKLSDGSYFGE-ICLLTR-GRRTASVRADTYCRLYSLSVDNFNEVLEEYPMMRRAF 652
Query: 853 WS-SLEITFNLRDTNMIPGSPGSTELEGG-FSRQRKRKLSFRRRTDKDTEQPGEVS---- 906
+ +++ + N I +L G F+ Q + + D++ Q E+
Sbjct: 653 ETVAIDRLDRIGKKNSILLHKVQHDLNSGVFNNQENAIIQEIVKYDREMVQQAELGQRVG 712
Query: 907 ---------------------------------ALGPGRAGAGPSSRGRPGGPWGESPSS 933
+GP G+ R P GP + S
Sbjct: 713 LFPPPPPPPQVTSAIATLQQAAAMSFCPQVARPLVGPLALGSPRLVRRPPPGPAPAAASP 772
Query: 934 GPSSPESSEDEGPGRSSSPLRLVPFSSPRP--PGEPPGGEPLMEDCEKSSDTCNPLSGA 990
GP P S PG +SP P +SP P P G L + S PLS +
Sbjct: 773 GPPPPASP----PGAPASP--RAPRTSPYGGLPAAPLAGPAL--PARRLSRASRPLSAS 823
Score = 31.6 bits (70), Expect = 4.6
Identities = 21/65 (32%), Positives = 24/65 (36%), Gaps = 9/65 (13%)
Query: 909 GPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPP 968
G GR G P + PG P P P+ P+ P P P P PP PP
Sbjct: 6 GGGRPGESPGATPAPGPP----PPPPPAPPQQQPPPPP-----PPAPPPGPGPAPPQHPP 56
Query: 969 GGEPL 973
E L
Sbjct: 57 RAEAL 61
Score = 31.2 bits (69), Expect = 6.0
Identities = 20/75 (26%), Positives = 25/75 (33%), Gaps = 13/75 (17%)
Query: 910 PGRAGAGPSSRGRPGGPWGE-SPSSGPSSPES------------SEDEGPGRSSSPLRLV 956
PG GA +++G P G G P P+ PE GP P
Sbjct: 85 PGTPGAASTAKGSPNGECGRGEPQCSPAGPEGPARGPKVSFSCRGAASGPAPGPGPAEEA 144
Query: 957 PFSSPRPPGEPPGGE 971
P GEP G +
Sbjct: 145 GSEEAGPAGEPRGSQ 159
>gi|38327037 hyperpolarization activated cyclic nucleotide-gated
potassium channel 3 [Homo sapiens]
Length = 774
Score = 171 bits (434), Expect = 3e-42
Identities = 127/476 (26%), Positives = 213/476 (44%), Gaps = 56/476 (11%)
Query: 398 WTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDL 457
W I YS F+ WD ++LLL++ + P F EE P P V ++
Sbjct: 84 WIIHPYSDFRFYWDLIMLLLMVGNLIVLPVGITFF---KEENSP---------PWIVFNV 131
Query: 458 IVDIMFIVDILINFRT-TYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSG 516
+ D F++D+++NFRT V E++ P I Y + WFL+D++++IP D +
Sbjct: 132 LSDTFFLLDLVLNFRTGIVVEEGAEILLAPRAIRTRYLRTWFLVDLISSIPVDYIFLVVE 191
Query: 517 SEELIG--LLKTARLLRLVRVAR--------KLDRYSEY--------------GAAV--L 550
E + + KTAR LR+VR + +L R Y +AV +
Sbjct: 192 LEPRLDAEVYKTARALRIVRFTKILSLLRLLRLSRLIRYIHQWEEIFHMTYDLASAVVRI 251
Query: 551 FLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDK 610
F L+ L+ HW C+ + + ++ D + H + G+ Y+
Sbjct: 252 FNLIGMMLLLCHWDGCLQFLVPMLQDFPPDCWVSINHMVNHSWGRQYSH----------- 300
Query: 611 YVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGT 670
AL+ S + +G+G +P + ++ M++G+ YA G+ +A+IQ L S
Sbjct: 301 ---ALFKAMSHMLCIGYGQQAPVGMPDVWLTMLSMIVGATCYAMFIGHATALIQSLDSSR 357
Query: 671 ARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICL 730
+Y + +V +++ FH++P RQR+ EY++H + D ++L E L+ +I
Sbjct: 358 RQYQEKYKQVEQYMSFHKLPADTRQRIHEYYEHRYQ-GKMFDEESILGELSEPLREEIIN 416
Query: 731 HLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEIL 790
R L+ H F A + A+ K + PGD +V G + +YFI G + +L
Sbjct: 417 FTCRGLVAHMPLFAHADPSFVTAVLTKLRFEVFQPGDLVVREGSVGRKMYFIQHGLLSVL 476
Query: 791 RGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYP 846
L FGE + L R G+ VRA TYC L+ + D VL+ +P
Sbjct: 477 ARGARDTRLTDGSYFGE-ICLLTR-GRRTASVRADTYCRLYSLSVDHFNAVLEEFP 530
>gi|120433600 cyclic nucleotide gated channel alpha 3 isoform 2
[Homo sapiens]
Length = 676
Score = 157 bits (398), Expect = 4e-38
Identities = 110/410 (26%), Positives = 203/410 (49%), Gaps = 37/410 (9%)
Query: 454 VVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHY-FKGWFLIDMVAAIPFDLLI 512
V+D D+++++D+L+ RT ++ +VS R+ HY F +D+++ +P DL
Sbjct: 187 VLDYSADVLYVLDVLVRARTGFLEQGL-MVSDTNRLWQHYKTTTQFKLDVLSLVPTDLAY 245
Query: 513 FGSGSEELIGLLKTARLLRLVRVARKLDRYS---------EYGAAVLFLLMCTFALIAHW 563
G+ ++ RLL+ R+ DR G VL++L +I HW
Sbjct: 246 LKVGTN--YPEVRFNRLLKFSRLFEFFDRTETRTNYPNMFRIGNLVLYIL-----IIIHW 298
Query: 564 LACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLT 623
ACI++AI DS W++ I P + + KY+ +LY++ +LT
Sbjct: 299 NACIYFAISKFIGFGTDS---WVY---PNISIPEHGR------LSRKYIYSLYWSTLTLT 346
Query: 624 SVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREF 683
++G P + E +F + L+G L++A+I GNV ++I + + A + ++ ++++
Sbjct: 347 TIG-ETPPPVKDEEYLFVVVDFLVGVLIFATIVGNVGSMISNMNASRAEFQAKIDSIKQY 405
Query: 684 IRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPF 743
++F ++ L R+ +F + W+ +D VLK P+ L+A+I ++++ L+ + F
Sbjct: 406 MQFRKVTKDLETRVIRWFDYLWANKKTVDEKEVLKSLPDKLKAEIAINVHLDTLKKVRIF 465
Query: 744 RGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVV--AILGK 801
+ G L L +K + T PGD + GD+ +Y I+ G + ++ D V +L
Sbjct: 466 QDCEAGLLVELVLKLRPTVFSPGDYICKKGDIGKEMYIINEGKLAVVADDGVTQFVVLSD 525
Query: 802 NDIFGEPLNLYARPGKS----NGDVRALTYCDLHKIHRDDLLEVLDMYPE 847
FGE L + KS ++R++ Y DL + +DDL+E L YPE
Sbjct: 526 GSYFGEISILNIKGSKSGNRRTANIRSIGYSDLFCLSKDDLMEALTEYPE 575
>gi|4502917 cyclic nucleotide gated channel alpha 3 isoform 1 [Homo
sapiens]
Length = 694
Score = 157 bits (398), Expect = 4e-38
Identities = 110/410 (26%), Positives = 203/410 (49%), Gaps = 37/410 (9%)
Query: 454 VVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHY-FKGWFLIDMVAAIPFDLLI 512
V+D D+++++D+L+ RT ++ +VS R+ HY F +D+++ +P DL
Sbjct: 205 VLDYSADVLYVLDVLVRARTGFLEQGL-MVSDTNRLWQHYKTTTQFKLDVLSLVPTDLAY 263
Query: 513 FGSGSEELIGLLKTARLLRLVRVARKLDRYS---------EYGAAVLFLLMCTFALIAHW 563
G+ ++ RLL+ R+ DR G VL++L +I HW
Sbjct: 264 LKVGTN--YPEVRFNRLLKFSRLFEFFDRTETRTNYPNMFRIGNLVLYIL-----IIIHW 316
Query: 564 LACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLT 623
ACI++AI DS W++ I P + + KY+ +LY++ +LT
Sbjct: 317 NACIYFAISKFIGFGTDS---WVY---PNISIPEHGR------LSRKYIYSLYWSTLTLT 364
Query: 624 SVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREF 683
++G P + E +F + L+G L++A+I GNV ++I + + A + ++ ++++
Sbjct: 365 TIG-ETPPPVKDEEYLFVVVDFLVGVLIFATIVGNVGSMISNMNASRAEFQAKIDSIKQY 423
Query: 684 IRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPF 743
++F ++ L R+ +F + W+ +D VLK P+ L+A+I ++++ L+ + F
Sbjct: 424 MQFRKVTKDLETRVIRWFDYLWANKKTVDEKEVLKSLPDKLKAEIAINVHLDTLKKVRIF 483
Query: 744 RGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVV--AILGK 801
+ G L L +K + T PGD + GD+ +Y I+ G + ++ D V +L
Sbjct: 484 QDCEAGLLVELVLKLRPTVFSPGDYICKKGDIGKEMYIINEGKLAVVADDGVTQFVVLSD 543
Query: 802 NDIFGEPLNLYARPGKS----NGDVRALTYCDLHKIHRDDLLEVLDMYPE 847
FGE L + KS ++R++ Y DL + +DDL+E L YPE
Sbjct: 544 GSYFGEISILNIKGSKSGNRRTANIRSIGYSDLFCLSKDDLMEALTEYPE 593
>gi|217035093 cyclic nucleotide gated channel alpha 1 isoform 1
[Homo sapiens]
Length = 759
Score = 148 bits (373), Expect = 3e-35
Identities = 101/402 (25%), Positives = 196/402 (48%), Gaps = 21/402 (5%)
Query: 454 VVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIF 513
++D + DI++++D+ + RT Y+ V I + F +D+++ IP DLL F
Sbjct: 271 ILDYVSDIVYLIDMFVRTRTGYLEQGLLVKEELKLINKYKSNLQFKLDVLSLIPTDLLYF 330
Query: 514 GSG-SEELIGLLKTARLLRLVRVARKLDRYSEYGAAV-LFLLMCTFALIAHWLACIWYAI 571
G + I L + R R+ ++ + + Y + L+ +I HW AC++Y+I
Sbjct: 331 KLGWNYPEIRLNRLLRFSRMFEFFQRTETRTNYPNIFRISNLVMYIVIIIHWNACVFYSI 390
Query: 572 GNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVS 631
D+ W++ N G + KYV +LY++ +LT++G
Sbjct: 391 SKAIGFGNDT---WVY-------PDINDPEFG--RLARKYVYSLYWSTLTLTTIG-ETPP 437
Query: 632 PNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPN 691
P +SE +F + LIG L++A+I GN+ ++I + + A + ++ +++++ F +
Sbjct: 438 PVRDSEYVFVVVDFLIGVLIFATIVGNIGSMISNMNAARAEFQARIDAIKQYMHFRNVSK 497
Query: 692 PLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCL 751
+ +R+ ++F + W+ +D VLK P+ L+A+I ++++ L+ + F G L
Sbjct: 498 DMEKRVIKWFDYLWTNKKTVDEKEVLKYLPDKLRAEIAINVHLDTLKKVRIFADCEAGLL 557
Query: 752 RALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVV--AILGKNDIFGEPL 809
L +K + PGD + GD+ +Y I G + ++ D V +L FGE
Sbjct: 558 VELVLKLQPQVYSPGDYICKKGDIGREMYIIKEGKLAVVADDGVTQFVVLSDGSYFGEIS 617
Query: 810 NLYARPGKS----NGDVRALTYCDLHKIHRDDLLEVLDMYPE 847
L + K+ +++++ Y DL + +DDL+E L YP+
Sbjct: 618 ILNIKGSKAGNRRTANIKSIGYSDLFCLSKDDLMEALTEYPD 659
>gi|71143141 cyclic nucleotide gated channel alpha 1 isoform 2 [Homo
sapiens]
Length = 690
Score = 148 bits (373), Expect = 3e-35
Identities = 101/402 (25%), Positives = 196/402 (48%), Gaps = 21/402 (5%)
Query: 454 VVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIF 513
++D + DI++++D+ + RT Y+ V I + F +D+++ IP DLL F
Sbjct: 202 ILDYVSDIVYLIDMFVRTRTGYLEQGLLVKEELKLINKYKSNLQFKLDVLSLIPTDLLYF 261
Query: 514 GSG-SEELIGLLKTARLLRLVRVARKLDRYSEYGAAV-LFLLMCTFALIAHWLACIWYAI 571
G + I L + R R+ ++ + + Y + L+ +I HW AC++Y+I
Sbjct: 262 KLGWNYPEIRLNRLLRFSRMFEFFQRTETRTNYPNIFRISNLVMYIVIIIHWNACVFYSI 321
Query: 572 GNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVS 631
D+ W++ N G + KYV +LY++ +LT++G
Sbjct: 322 SKAIGFGNDT---WVY-------PDINDPEFG--RLARKYVYSLYWSTLTLTTIG-ETPP 368
Query: 632 PNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPN 691
P +SE +F + LIG L++A+I GN+ ++I + + A + ++ +++++ F +
Sbjct: 369 PVRDSEYVFVVVDFLIGVLIFATIVGNIGSMISNMNAARAEFQARIDAIKQYMHFRNVSK 428
Query: 692 PLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCL 751
+ +R+ ++F + W+ +D VLK P+ L+A+I ++++ L+ + F G L
Sbjct: 429 DMEKRVIKWFDYLWTNKKTVDEKEVLKYLPDKLRAEIAINVHLDTLKKVRIFADCEAGLL 488
Query: 752 RALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVV--AILGKNDIFGEPL 809
L +K + PGD + GD+ +Y I G + ++ D V +L FGE
Sbjct: 489 VELVLKLQPQVYSPGDYICKKGDIGREMYIIKEGKLAVVADDGVTQFVVLSDGSYFGEIS 548
Query: 810 NLYARPGKS----NGDVRALTYCDLHKIHRDDLLEVLDMYPE 847
L + K+ +++++ Y DL + +DDL+E L YP+
Sbjct: 549 ILNIKGSKAGNRRTANIKSIGYSDLFCLSKDDLMEALTEYPD 590
>gi|42718011 cyclic nucleotide gated channel alpha 2 [Homo sapiens]
Length = 664
Score = 140 bits (352), Expect = 9e-33
Identities = 107/418 (25%), Positives = 194/418 (46%), Gaps = 53/418 (12%)
Query: 454 VVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGW-FLIDMVAAIPFDLLI 512
V+D + D+++I D+ I RT ++ +V ++ +Y F +D+ + IP DL+
Sbjct: 177 VLDYVSDVVYIADLFIRLRTGFLEQGL-LVKDTKKLRDNYIHTLQFKLDVASIIPTDLIY 235
Query: 513 FGSGSEELIGLLKTARLLRLVRVARKLDRYS---------EYGAAVLFLLMCTFALIAHW 563
F ++ RLL R+ DR VL++L+ I HW
Sbjct: 236 FAVDIHS--PEVRFNRLLHFARMFEFFDRTETRTNYPNIFRISNLVLYILV-----IIHW 288
Query: 564 LACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKD--------KYVTAL 615
ACI+YAI +D+ W++ P+I D +Y+ L
Sbjct: 289 NACIYYAISKSIGFGVDT---WVY-----------------PNITDPEYGYLAREYIYCL 328
Query: 616 YFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHT 675
Y++ +LT++G P + E +F I LIG L++A+I GNV ++I + + A +
Sbjct: 329 YWSTLTLTTIG-ETPPPVKDEEYLFVIFDFLIGVLIFATIVGNVGSMISNMNATRAEFQA 387
Query: 676 QMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRS 735
++ V+ +++F ++ + ++ +F + W+ +D +LK P L+A+I ++++ S
Sbjct: 388 KIDAVKHYMQFRKVSKGMEAKVIRWFDYLWTNKKTVDEREILKNLPAKLRAEIAINVHLS 447
Query: 736 LLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVV 795
L+ + F G L L +K + PGD + GD+ +Y I G + ++ D V
Sbjct: 448 TLKKVRIFHDCEAGLLVELVLKLRPQVFSPGDYICRKGDIGKEMYIIKEGKLAVVADDGV 507
Query: 796 V--AILGKNDIFGEPLNLYARPGK----SNGDVRALTYCDLHKIHRDDLLEVLDMYPE 847
A+L FGE L + K ++R+L Y DL + +DDL+E + YP+
Sbjct: 508 TQYALLSAGSCFGEISILNIKGSKMGNRRTANIRSLGYSDLFCLSKDDLMEAVTEYPD 565
>gi|82617546 cyclic nucleotide gated channel alpha 4 [Homo sapiens]
Length = 575
Score = 133 bits (335), Expect = 9e-31
Identities = 100/419 (23%), Positives = 201/419 (47%), Gaps = 30/419 (7%)
Query: 441 PATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGW-FL 499
P + GY L V+D D+++++D+++ F T ++ VV GRI+ Y + W F
Sbjct: 59 PDLQHGYLVAWL-VLDYTSDLLYLLDMVVRFHTGFLEQGILVVDK-GRISSRYVRTWSFF 116
Query: 500 IDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEY----GAAVLFLLMC 555
+D+ + +P D++ G L+ R LR R+ DR A + LM
Sbjct: 117 LDLASLMPTDVVYVRLGPHT--PTLRLNRFLRAPRLFEAFDRTETRTAYPNAFRIAKLML 174
Query: 556 TFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTAL 615
++ HW +C+++A+ D+ W++ + + G ++ +Y+ +
Sbjct: 175 YIFVVIHWNSCLYFALSRYLGFGRDA---WVYP---------DPAQPGFERLRRQYLYSF 222
Query: 616 YFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHT 675
YF+ LT+VG P E +F + L+ + +A+I G++S++I + + A ++
Sbjct: 223 YFSTLILTTVG-DTPPPAREEEYLFMVGDFLLAVMGFATIMGSMSSVIYNMNTADAAFYP 281
Query: 676 QMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRS 735
V+++++ + L +R+ +++QH + A+L+ PE L+A++ + ++ S
Sbjct: 282 DHALVKKYMKLQHVNRKLERRVIDWYQHLQINKKMTNEVAILQHLPERLRAEVAVSVHLS 341
Query: 736 LLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVV 795
L + F+ L L +K + PG+ + GD+ +Y I G + ++ D +
Sbjct: 342 TLSRVQIFQNCEASLLEELVLKLQPQTYSPGEYVCRKGDIGQEMYIIREGQLAVVADDGI 401
Query: 796 V--AILGKNDIFGEPLNLYARPGKSNG-----DVRALTYCDLHKIHRDDLLEVLDMYPE 847
A+LG FGE +++ G +G ++++L Y DL + ++DL EVL YP+
Sbjct: 402 TQYAVLGAGLYFGE-ISIINIKGNMSGNRRTANIKSLGYSDLFCLSKEDLREVLSEYPQ 459
>gi|116642889 cyclic nucleotide gated channel beta 3 [Homo sapiens]
Length = 809
Score = 99.8 bits (247), Expect = 1e-20
Identities = 106/511 (20%), Positives = 208/511 (40%), Gaps = 50/511 (9%)
Query: 350 ASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLP--EY--KLQAPR-IHRWTILHYS 404
ASP + + P +KE TE ++L +P EY +++ P I +T Y
Sbjct: 160 ASPQTAKPTAVPPVKESDDKPTEHYYRLLWFKVKKMPLTEYLKRIKLPNSIDSYTDRLY- 218
Query: 405 PFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFI 464
+W L+ L + F P F + + + D+I DI+++
Sbjct: 219 ---LLWLLLVTLAYNWNCCFIPLRLVFPYQTADN----------IHYWLIADIICDIIYL 265
Query: 465 VDIL-INFRTTYVNANEEVVSHPGRIAVHYFKGW-FLIDMVAAIPFDLLIFGSGSEELIG 522
D+L I R +V + +V + HY F +D+ + IPFD+ G +
Sbjct: 266 YDMLFIQPRLQFVRGGDIIVDS-NELRKHYRTSTKFQLDVASIIPFDICYLFFGFNPMFR 324
Query: 523 LLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFAL-IAHWLACIWYAIGNMEQPHMDS 581
+ + L+ + + + L I H AC++Y N E
Sbjct: 325 ANRMLKYTSFFEFNHHLESIMDKAYIYRVIRTTGYLLFILHINACVYYWASNYEGI---G 381
Query: 582 RIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFS 641
W+ Y+ G ++Y+ Y+ +L ++G G P T E +F
Sbjct: 382 TTRWV----------YDGEG-------NEYLRCYYWAVRTLITIG-GLPEPQTLFEIVFQ 423
Query: 642 ICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYF 701
+ G +++S+ G + +I + + M ++ + IP +++R+ ++
Sbjct: 424 LLNFFSGVFVFSSLIGQMRDVIGAATANQNYFRACMDDTIAYMNNYSIPKLVQKRVRTWY 483
Query: 702 QHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTT 761
++ W +D + +LK P +Q + + +N S++ F+G + + ++ K+
Sbjct: 484 EYTWDSQRMLDESDLLKTLPTTVQLALAIDVNFSIISKVDLFKGCDTQMIYDMLLRLKSV 543
Query: 762 HAPPGDTLVHAGDLLTALYFISRGSIEIL---RGDVVVAILGKNDIFGEPLNLYARPG-- 816
PGD + G++ +Y I G +++L G V+ L +FGE ++L A G
Sbjct: 544 LYLPGDFVCKKGEIGKEMYIIKHGEVQVLGGPDGTKVLVTLKAGSVFGE-ISLLAAGGGN 602
Query: 817 KSNGDVRALTYCDLHKIHRDDLLEVLDMYPE 847
+ +V A + +L + + L E+L YP+
Sbjct: 603 RRTANVVAHGFANLLTLDKKTLQEILVHYPD 633
>gi|114205399 cyclic nucleotide gated channel beta 1 isoform a [Homo
sapiens]
Length = 1251
Score = 98.2 bits (243), Expect = 4e-20
Identities = 80/404 (19%), Positives = 185/404 (45%), Gaps = 35/404 (8%)
Query: 454 VVDLIVDIMFIVDILI-NFRTTYVNANEEVVSHPGRIAVHYFKGW-FLIDMVAAIPFDLL 511
++D + D+++ +DI + R +V + +++ + +Y K F +D+++ +P D L
Sbjct: 693 LMDYLCDLIYFLDITVFQTRLQFVRGGD-IITDKKDMRNNYLKSRRFKMDLLSLLPLDFL 751
Query: 512 IFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWL---ACIW 568
G L+ L + + + +L+ S A ++ ++ T A + + L +C++
Sbjct: 752 YLKVGVNPLLRLPRCLKYMAFFEFNSRLE--SILSKAYVYRVIRTTAYLLYSLHLNSCLY 809
Query: 569 YAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFG 628
Y + +G H + D +G + Y+ YF +L ++G G
Sbjct: 810 YWASAYQG------LGSTHWVYDGVG--------------NSYIRCYYFAVKTLITIG-G 848
Query: 629 NVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQ 688
P T E +F + G ++ + G + ++ +G Y + M +++ F++
Sbjct: 849 LPDPKTLFEIVFQLLNYFTGVFAFSVMIGQMRDVVGAATAGQTYYRSCMDSTVKYMNFYK 908
Query: 689 IPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATK 748
IP ++ R++ ++++ W +D + ++ P+ ++ D+ + +N +++ F+G +
Sbjct: 909 IPKSVQNRVKTWYEYTWHSQGMLDESELMVQLPDKMRLDLAIDVNYNIVSKVALFQGCDR 968
Query: 749 GCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEIL---RGDVVVAILGKNDIF 805
+ + + ++ P D + G++ +Y I G +++L G V+ L +F
Sbjct: 969 QMIFDMLKRLRSVVYLPNDYVCKKGEIGREMYIIQAGQVQVLGGPDGKSVLVTLKAGSVF 1028
Query: 806 GEPLNLYARPG--KSNGDVRALTYCDLHKIHRDDLLEVLDMYPE 847
GE ++L A G + +V A + +L + + DL E+L YPE
Sbjct: 1029 GE-ISLLAVGGGNRRTANVVAHGFTNLFILDKKDLNEILVHYPE 1071
>gi|34365793 WNK lysine deficient protein kinase 4 [Homo sapiens]
Length = 1243
Score = 48.1 bits (113), Expect = 5e-05
Identities = 61/222 (27%), Positives = 82/222 (36%), Gaps = 27/222 (12%)
Query: 932 SSGPSSPESSEDE-GPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGA 990
SS P +P S + PG SP + P +SP P P+ S+ + +P S
Sbjct: 804 SSSPGTPLSPGNPFSPGTPISPGPIFPITSPPCHPSPSPFSPISSQVS-SNPSPHPTSSP 862
Query: 991 FSGVSNIFSFWGDSRGRQYQELPRCPAPT--PSLLNIPLSSPGRRPRGDVESRLDALQRQ 1048
S+ F + LP PT P+ + LSSP P S
Sbjct: 863 LPFSSSTPEFPVPLSQCPWSSLPTTSPPTFSPTCSQVTLSSPFFPPCPSTSSFPSTTAAP 922
Query: 1049 LNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTL--- 1105
L L + S + TV Q L +P PG S SP P SPLP+L L
Sbjct: 923 LLSLASAFSLAVMTVAQSL--------------LSPSPGLLSQSPPAPPSPLPSLPLPPP 968
Query: 1106 ------DSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQ 1141
+S S + + E PP A LP E +S G+
Sbjct: 969 VAPGGQESPSPHTAEVESEASPPPARPLPGEARLAPISEEGK 1010
>gi|5031767 heat shock transcription factor 1 [Homo sapiens]
Length = 529
Score = 45.8 bits (107), Expect = 2e-04
Identities = 63/236 (26%), Positives = 92/236 (38%), Gaps = 33/236 (13%)
Query: 930 SPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEP------PGGEPLMEDCEKSSDT 983
+P+S +SP S DE P SSSPL V P PP P PG ++ +
Sbjct: 272 APASPMASPGGSIDERP-LSSSPLVRVKEEPPSPPQSPRVEEASPGRPSSVDTLLSPTAL 330
Query: 984 CNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLD 1043
+ + + D+RG E R P+P P+ S + ++ LD
Sbjct: 331 IDSILRESEPAPASVTALTDARGHTDTE-GRPPSPPPTSTPEKCLSVACLDKNELSDHLD 389
Query: 1044 ALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTL 1103
A+ L+ L+T LS+ +S T+ S S +P LP L
Sbjct: 390 AMDSNLDNLQTMLSSH-----------------GFSVDTSALLDLFSPSVTVPDMSLPDL 432
Query: 1104 TLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS 1159
SL+ + + ++ +E PP PE P QL T+QPL DPGS
Sbjct: 433 D-SSLASIQELLSPQE-PPRPPEAENSSP----DSGKQLVHYTAQPLFL--LDPGS 480
>gi|58530876 melanoma antigen family C, 1 [Homo sapiens]
Length = 1142
Score = 43.9 bits (102), Expect = 9e-04
Identities = 67/255 (26%), Positives = 97/255 (38%), Gaps = 56/255 (21%)
Query: 930 SPSSGPSS-PESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLM--EDCEKSSDTCNP 986
+PSS P S PESS+ G SPL S PP PL E + D+ +P
Sbjct: 636 TPSSLPQSFPESSQSPPEGPVQSPLH----SPQSPPEGMHSQSPLQSPESAPEGEDSLSP 691
Query: 987 LS---GAFSGVSNIFSF--------WGDS-----------RGRQYQELPRCPAP---TPS 1021
L G ++ S W DS +G +Q + P + +
Sbjct: 692 LQIPQSPLEGEDSLSSLHFPQSPPEWEDSLSPLHFPQFPPQGEDFQSSLQSPVSICSSST 751
Query: 1022 LLNIPLS---SPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAY 1078
L++P S SP P G +S LQR ++ S +A++LQ ++
Sbjct: 752 SLSLPQSFPESPQSPPEGPAQS---PLQRPVSSF---FSYTLASLLQ----------SSH 795
Query: 1079 SAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQ---VSQF--MACEELPPGAPELPQEGPT 1133
+ +P GP + PVS P+ T SLSQ VS F L +PE P + P
Sbjct: 796 ESPQSPPEGPAQSPLQSPVSSFPSSTSSSLSQSSPVSSFPSSTSSSLSKSSPESPLQSPV 855
Query: 1134 RRLSLPGQLGALTSQ 1148
S L + +
Sbjct: 856 ISFSSSTSLSPFSEE 870
Score = 31.2 bits (69), Expect = 6.0
Identities = 46/203 (22%), Positives = 76/203 (37%), Gaps = 43/203 (21%)
Query: 936 SSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCN---------- 985
SSPES++ G SPL++ PG P L+ + S + +
Sbjct: 356 SSPESAQSTFEGFPQSPLQI--------PGSPSFSSTLLSLFQSSPERTHSTFEGFPQSP 407
Query: 986 ---PLSGAFSG-VSNIFSFWGDSRGRQYQELPRCPAPTP-------SLLNIPLSSPGRRP 1034
P++ +FS + +I +S ++ P+ P P +LL++ SSP R
Sbjct: 408 LQIPMTSSFSSTLLSILQSSPESAQSAFEGFPQSPLQIPVSSSFSYTLLSLFQSSPER-- 465
Query: 1035 RGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAV--------TTPGP 1086
S + + ++ S+ +T+L L Q + +P
Sbjct: 466 ---THSTFEGFPQSPLQIPVSSSSSSSTLLSLFQSSPECTQSTFEGFPQSPLQIPQSPPE 522
Query: 1087 GPTSTSPLLPVSPLPTLTLDSLS 1109
G + SPL V LP DSLS
Sbjct: 523 GENTHSPLQIVPSLPEWE-DSLS 544
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.320 0.137 0.417
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 52,506,277
Number of Sequences: 37866
Number of extensions: 2897580
Number of successful extensions: 20490
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 103
Number of HSP's successfully gapped in prelim test: 654
Number of HSP's that attempted gapping in prelim test: 16900
Number of HSP's gapped (non-prelim): 3860
length of query: 1159
length of database: 18,247,518
effective HSP length: 113
effective length of query: 1046
effective length of database: 13,968,660
effective search space: 14611218360
effective search space used: 14611218360
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 68 (30.8 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.