Guide to the Human Genome
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Search of human proteins with 45505155

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|45505155 F-box protein 38 isoform a [Homo sapiens]
         (1113 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|45505155 F-box protein 38 isoform a [Homo sapiens]                2274   0.0  
gi|45545409 F-box protein 38 isoform b [Homo sapiens]                2097   0.0  
gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens]    57   7e-08
gi|148596949 nucleolar and coiled-body phosphoprotein 1 [Homo sa...    49   3e-05
gi|4504487 histidine rich calcium binding protein precursor [Hom...    41   0.006
gi|28372531 protein phosphatase 4, regulatory subunit 2 [Homo sa...    40   0.009
gi|62244004 modulator of estrogen induced transcription isoform ...    40   0.016
gi|207113164 Treacher Collins-Franceschetti syndrome 1 isoform f...    39   0.036
gi|207113162 Treacher Collins-Franceschetti syndrome 1 isoform e...    39   0.036
gi|207113160 Treacher Collins-Franceschetti syndrome 1 isoform d...    39   0.036
gi|57164975 Treacher Collins-Franceschetti syndrome 1 isoform b ...    39   0.036
gi|57164977 Treacher Collins-Franceschetti syndrome 1 isoform a ...    39   0.036
gi|57164979 Treacher Collins-Franceschetti syndrome 1 isoform c ...    39   0.036
gi|4758172 dentin matrix acidic phosphoprotein 1 isoform 1 precu...    38   0.047
gi|121256621 dentin matrix acidic phosphoprotein 1 isoform 2 pre...    38   0.047
gi|7656879 ALL1 fused gene from 5q31 [Homo sapiens]                    38   0.047
gi|33356174 pinin, desmosome associated protein [Homo sapiens]         38   0.061
gi|63054848 coiled-coil domain containing 34 isoform 1 [Homo sap...    37   0.080
gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens]        37   0.080
gi|116256485 chromosome 6 open reading frame 10 [Homo sapiens]         37   0.14 
gi|126362967 Nck-associated protein 5 isoform 1 [Homo sapiens]         36   0.18 
gi|21361272 myeloid/lymphoid or mixed-lineage leukemia (trithora...    36   0.18 
gi|239755326 PREDICTED: hypothetical protein [Homo sapiens]            36   0.18 
gi|122937227 U2-associated SR140 protein [Homo sapiens]                36   0.18 
gi|22035679 AT rich interactive domain 4B isoform 2 [Homo sapiens]     36   0.18 
gi|22035677 AT rich interactive domain 4B isoform 1 [Homo sapiens]     36   0.18 
gi|51873034 F-box and leucine-rich repeat protein 9 [Homo sapiens]     36   0.23 
gi|16306591 F-box and leucine-rich repeat protein 9 [Homo sapiens]     36   0.23 
gi|116875765 tight junction protein 1 isoform b [Homo sapiens]         35   0.30 
gi|116875767 tight junction protein 1 isoform a [Homo sapiens]         35   0.30 

>gi|45505155 F-box protein 38 isoform a [Homo sapiens]
          Length = 1113

 Score = 2274 bits (5893), Expect = 0.0
 Identities = 1113/1113 (100%), Positives = 1113/1113 (100%)

Query: 1    MGPRKKSVKTCIMNNEIPEEMTADETKDYMNQLSHEVLCHIFRYLPLQDIMCMECLSRKL 60
            MGPRKKSVKTCIMNNEIPEEMTADETKDYMNQLSHEVLCHIFRYLPLQDIMCMECLSRKL
Sbjct: 1    MGPRKKSVKTCIMNNEIPEEMTADETKDYMNQLSHEVLCHIFRYLPLQDIMCMECLSRKL 60

Query: 61   KEAVTLYLRVVRVVDLCAGRWWEYMPSGFTDASFLTLLKKMPDVEQLYGLHPRYLERRRV 120
            KEAVTLYLRVVRVVDLCAGRWWEYMPSGFTDASFLTLLKKMPDVEQLYGLHPRYLERRRV
Sbjct: 61   KEAVTLYLRVVRVVDLCAGRWWEYMPSGFTDASFLTLLKKMPDVEQLYGLHPRYLERRRV 120

Query: 121  RGHEAFSIPGVLEALQACPNLVGVETSHLELVESIWTYMPHVHILGKFRNRNGAFPIPPE 180
            RGHEAFSIPGVLEALQACPNLVGVETSHLELVESIWTYMPHVHILGKFRNRNGAFPIPPE
Sbjct: 121  RGHEAFSIPGVLEALQACPNLVGVETSHLELVESIWTYMPHVHILGKFRNRNGAFPIPPE 180

Query: 181  NKLKIPIGAKIQTLHLVGVNVPEIPCIPMLRHLYMKWVRLTKPQPFKDFLCISLRTFVMR 240
            NKLKIPIGAKIQTLHLVGVNVPEIPCIPMLRHLYMKWVRLTKPQPFKDFLCISLRTFVMR
Sbjct: 181  NKLKIPIGAKIQTLHLVGVNVPEIPCIPMLRHLYMKWVRLTKPQPFKDFLCISLRTFVMR 240

Query: 241  NCAGPTNSLKYVPLVTGLASARNLEHLEMVRVPFLGGLIQHVVEDSWRSGGFRNLHTIVL 300
            NCAGPTNSLKYVPLVTGLASARNLEHLEMVRVPFLGGLIQHVVEDSWRSGGFRNLHTIVL
Sbjct: 241  NCAGPTNSLKYVPLVTGLASARNLEHLEMVRVPFLGGLIQHVVEDSWRSGGFRNLHTIVL 300

Query: 301  GACKNALEVDLGYLIITAARRLHEVRIQPSLTKDGVFSALKMAELEFPQFETLHLGYVDE 360
            GACKNALEVDLGYLIITAARRLHEVRIQPSLTKDGVFSALKMAELEFPQFETLHLGYVDE
Sbjct: 301  GACKNALEVDLGYLIITAARRLHEVRIQPSLTKDGVFSALKMAELEFPQFETLHLGYVDE 360

Query: 361  FLLQSRMANADLVKYGLADVVENPGIITDIGMKAVNEVFSCIKYLAIYNCPHLHNPYNWI 420
            FLLQSRMANADLVKYGLADVVENPGIITDIGMKAVNEVFSCIKYLAIYNCPHLHNPYNWI
Sbjct: 361  FLLQSRMANADLVKYGLADVVENPGIITDIGMKAVNEVFSCIKYLAIYNCPHLHNPYNWI 420

Query: 421  SDHSRWTRLVDINLVRCHALKLDSFGQFIELLPSLEFISLDQMFREPPKGCARVGLSAGT 480
            SDHSRWTRLVDINLVRCHALKLDSFGQFIELLPSLEFISLDQMFREPPKGCARVGLSAGT
Sbjct: 421  SDHSRWTRLVDINLVRCHALKLDSFGQFIELLPSLEFISLDQMFREPPKGCARVGLSAGT 480

Query: 481  GIGVSSALVSNQNSNNDDNNAQNNNANIHDNNHHHPDDSDEENDFRQDLQPGEQQFAADA 540
            GIGVSSALVSNQNSNNDDNNAQNNNANIHDNNHHHPDDSDEENDFRQDLQPGEQQFAADA
Sbjct: 481  GIGVSSALVSNQNSNNDDNNAQNNNANIHDNNHHHPDDSDEENDFRQDLQPGEQQFAADA 540

Query: 541  LNEMEDIVQEDGEVVAESGNNTPAHSQAIIPVDVDEEQAGPSGLQRVVKPTSITVHDSES 600
            LNEMEDIVQEDGEVVAESGNNTPAHSQAIIPVDVDEEQAGPSGLQRVVKPTSITVHDSES
Sbjct: 541  LNEMEDIVQEDGEVVAESGNNTPAHSQAIIPVDVDEEQAGPSGLQRVVKPTSITVHDSES 600

Query: 601  DDEEDSLELQEVWIPKNGTRRYSEREEKTGESVQSRELSVSGKGKTPLRKRYNSHQMGQS 660
            DDEEDSLELQEVWIPKNGTRRYSEREEKTGESVQSRELSVSGKGKTPLRKRYNSHQMGQS
Sbjct: 601  DDEEDSLELQEVWIPKNGTRRYSEREEKTGESVQSRELSVSGKGKTPLRKRYNSHQMGQS 660

Query: 661  KQFPLEESSCEKGCQVTSEQIKADMKAARDIPEKKKNKDVYPSCSSTTASTVGNSSSHNT 720
            KQFPLEESSCEKGCQVTSEQIKADMKAARDIPEKKKNKDVYPSCSSTTASTVGNSSSHNT
Sbjct: 661  KQFPLEESSCEKGCQVTSEQIKADMKAARDIPEKKKNKDVYPSCSSTTASTVGNSSSHNT 720

Query: 721  ASQSPDFVRTVNSGGSSEPSPTEVDVSRQCACSPGGSEDSEAMEEGDAESSVCPRCCCHR 780
            ASQSPDFVRTVNSGGSSEPSPTEVDVSRQCACSPGGSEDSEAMEEGDAESSVCPRCCCHR
Sbjct: 721  ASQSPDFVRTVNSGGSSEPSPTEVDVSRQCACSPGGSEDSEAMEEGDAESSVCPRCCCHR 780

Query: 781  PQESQRRTSRCSDEERPSTSRACVVNGPDEVAKTKPRHAMKRKRTADKSTSTSDPVIEDD 840
            PQESQRRTSRCSDEERPSTSRACVVNGPDEVAKTKPRHAMKRKRTADKSTSTSDPVIEDD
Sbjct: 781  PQESQRRTSRCSDEERPSTSRACVVNGPDEVAKTKPRHAMKRKRTADKSTSTSDPVIEDD 840

Query: 841  HVQVLVLKSKNLVGVTMTNCGITDLVLKDCPKMMFIHATRCRVLKHLKVENAPIVNRFDY 900
            HVQVLVLKSKNLVGVTMTNCGITDLVLKDCPKMMFIHATRCRVLKHLKVENAPIVNRFDY
Sbjct: 841  HVQVLVLKSKNLVGVTMTNCGITDLVLKDCPKMMFIHATRCRVLKHLKVENAPIVNRFDY 900

Query: 901  AQCKKLNMDQVLDQILRMPPERNRIIYLRPMQQVDTLTLEQKLFSGPYPYHICIIHEFSN 960
            AQCKKLNMDQVLDQILRMPPERNRIIYLRPMQQVDTLTLEQKLFSGPYPYHICIIHEFSN
Sbjct: 901  AQCKKLNMDQVLDQILRMPPERNRIIYLRPMQQVDTLTLEQKLFSGPYPYHICIIHEFSN 960

Query: 961  PPNVRNKVRIRSWMDTIANINQELIKYEFFPEATRSEEDLKKYPKYPWGREIYTLEGVVD 1020
            PPNVRNKVRIRSWMDTIANINQELIKYEFFPEATRSEEDLKKYPKYPWGREIYTLEGVVD
Sbjct: 961  PPNVRNKVRIRSWMDTIANINQELIKYEFFPEATRSEEDLKKYPKYPWGREIYTLEGVVD 1020

Query: 1021 GAPYSMISDFPWLRSLRAAEPNSFARYDFEDDEESTIYAPRRKGQLSADICMETIGEEIS 1080
            GAPYSMISDFPWLRSLRAAEPNSFARYDFEDDEESTIYAPRRKGQLSADICMETIGEEIS
Sbjct: 1021 GAPYSMISDFPWLRSLRAAEPNSFARYDFEDDEESTIYAPRRKGQLSADICMETIGEEIS 1080

Query: 1081 EMRQMKKGVFQRVVAIFIHYCDVNGEPVEDDYI 1113
            EMRQMKKGVFQRVVAIFIHYCDVNGEPVEDDYI
Sbjct: 1081 EMRQMKKGVFQRVVAIFIHYCDVNGEPVEDDYI 1113


>gi|45545409 F-box protein 38 isoform b [Homo sapiens]
          Length = 1188

 Score = 2097 bits (5434), Expect = 0.0
 Identities = 1057/1188 (88%), Positives = 1065/1188 (89%), Gaps = 75/1188 (6%)

Query: 1    MGPRKKSVKTCIMNNEIPEEMTADETKDYMNQLSHEVLCHIFRYLPLQDIMCMECLSRKL 60
            MGPRKKSVKTCIMNNEIPEEMTADETKDYMNQLSHEVLCHIFRYLPLQDIMCMECLSRKL
Sbjct: 1    MGPRKKSVKTCIMNNEIPEEMTADETKDYMNQLSHEVLCHIFRYLPLQDIMCMECLSRKL 60

Query: 61   KEAVTLYLRVVRVVDLCAGRWWEYMPSGFTDASFLTLLKKMPDVEQLYGLHPRYLERRRV 120
            KEAVTLYLRVVRVVDLCAGRWWEYMPSGFTDASFLTLLKKMPDVEQLYGLHPRYLERRRV
Sbjct: 61   KEAVTLYLRVVRVVDLCAGRWWEYMPSGFTDASFLTLLKKMPDVEQLYGLHPRYLERRRV 120

Query: 121  RGHEAFSIPGVLEALQACPNLVGVETSHLELVESIWTYMPHVHILGKFRNRNGAFPIPPE 180
            RGHEAFSIPGVLEALQACPNLVGVETSHLELVESIWTYMPHVHILGKFRNRNGAFPIPPE
Sbjct: 121  RGHEAFSIPGVLEALQACPNLVGVETSHLELVESIWTYMPHVHILGKFRNRNGAFPIPPE 180

Query: 181  NKLKIPIGAKIQTLHLVGVNVPEIPCIPMLRHLYMKWVRLTKPQPFKDFLCISLRTFVMR 240
            NKLKIPIGAKIQTLHLVGVNVPEIPCIPMLRHLYMKWVRLTKPQPFKDFLCISLRTFVMR
Sbjct: 181  NKLKIPIGAKIQTLHLVGVNVPEIPCIPMLRHLYMKWVRLTKPQPFKDFLCISLRTFVMR 240

Query: 241  NCAGPTNSLKYVPLVTGLASARNLEHLEMVRVPFLGGLIQHVVEDSWRSGGFRNLHTIVL 300
            NCAGPTNSLKYVPLVTGLASARNLEHLEMVRVPFLGGLIQHVVEDSWRSGGFRNLHTIVL
Sbjct: 241  NCAGPTNSLKYVPLVTGLASARNLEHLEMVRVPFLGGLIQHVVEDSWRSGGFRNLHTIVL 300

Query: 301  GACKNALEVDLGYLIITAARRLHEVRIQPSLTKDGVFSALKMAELEFPQFETLHLGYVDE 360
            GACKNALEVDLGYLIITAARRLHEVRIQPSLTKDGVFSALKMAELEFPQFETLHLGYVDE
Sbjct: 301  GACKNALEVDLGYLIITAARRLHEVRIQPSLTKDGVFSALKMAELEFPQFETLHLGYVDE 360

Query: 361  FLLQSRMANADLVKYGLADVVENPGIITDIGMKAVNEVFSCIKYLAIYNCPHLHNPYNWI 420
            FLLQSRMANADLVKYGLADVVENPGIITDIGMKAVNEVFSCIKYLAIYNCPHLHNPYNWI
Sbjct: 361  FLLQSRMANADLVKYGLADVVENPGIITDIGMKAVNEVFSCIKYLAIYNCPHLHNPYNWI 420

Query: 421  SDHSRWTRLVDINLVRCHALKLDSFGQFIELLPSLEFISLDQMFREPPKGCARVGLSAGT 480
            SDHSRWTRLVDINLVRCHALKLDSFGQFIELLPSLEFISLDQMFREPPKGCARVGLSAGT
Sbjct: 421  SDHSRWTRLVDINLVRCHALKLDSFGQFIELLPSLEFISLDQMFREPPKGCARVGLSAGT 480

Query: 481  GIGVSSALVSNQNSNNDDNNAQNNNANIHDNNHHHPDDSDEENDFRQDLQPGEQQFAADA 540
            GIGVSSALVSNQNSNNDDNNAQNNNANIHDNNHHHPDDSDEENDFRQDLQPGEQQFAADA
Sbjct: 481  GIGVSSALVSNQNSNNDDNNAQNNNANIHDNNHHHPDDSDEENDFRQDLQPGEQQFAADA 540

Query: 541  LNEMEDIVQEDGEVVAESGNNTPAHSQAIIPVDVDEEQAGPSGLQRVVKPTSITVHDSES 600
            LNEMEDIVQEDGEVVAESGNNTPAHSQAIIPVDVDEEQAGPSGLQRVVKPTSITVHDSES
Sbjct: 541  LNEMEDIVQEDGEVVAESGNNTPAHSQAIIPVDVDEEQAGPSGLQRVVKPTSITVHDSES 600

Query: 601  DDEEDSLELQEVWIPKNGTRRYSEREEKTGESVQSRELSVSGKGKTPLRKRYNSHQMGQS 660
            DDEEDSLELQEVWIPKNGTRRYSEREEKTGESVQSRELSVSGKGKTPLRKRYNSHQMGQS
Sbjct: 601  DDEEDSLELQEVWIPKNGTRRYSEREEKTGESVQSRELSVSGKGKTPLRKRYNSHQMGQS 660

Query: 661  KQFPLEESSCEKGCQVTSEQIKADMKAARDIPEKKKNKDVYPSCSSTTASTVGNSSSHNT 720
            KQFPLEESSCEKGCQVTSEQIKADMKAARDIPEKKKNKDVYPSCSSTTASTVGNSSSHNT
Sbjct: 661  KQFPLEESSCEKGCQVTSEQIKADMKAARDIPEKKKNKDVYPSCSSTTASTVGNSSSHNT 720

Query: 721  ASQSPDFVRTVNSGGSS--------------------------EPSPTEVDVSRQCACSP 754
            ASQSPDFVRTVNSGGSS                          E    E  V  +C C  
Sbjct: 721  ASQSPDFVRTVNSGGSSEPSPTEVDVSRQCACSPGGSEDSEAMEEGDAESSVCPRCCCHR 780

Query: 755  GGSEDSEAMEEGDAESSVCPRCCCHRPQESQRRT------------------------SR 790
                        D E     R C     +  R                          S 
Sbjct: 781  PQESQRRTSRCSDEERPSTSRACVVNGPDGTRSAFSFRTLPQGGSSGPAHDERTNGSGSG 840

Query: 791  CSDEERPSTSR--ACVVNGPD-----------------------EVAKTKPRHAMKRKRT 825
             + E+R  +S+  +C V   +                       EVAKTKPRHAMKRKRT
Sbjct: 841  ATGEDRRGSSQPESCDVQSNEDYPRRPLTRARSRLSHVLLVSESEVAKTKPRHAMKRKRT 900

Query: 826  ADKSTSTSDPVIEDDHVQVLVLKSKNLVGVTMTNCGITDLVLKDCPKMMFIHATRCRVLK 885
            ADKSTSTSDPVIEDDHVQVLVLKSKNLVGVTMTNCGITDLVLKDCPKMMFIHATRCRVLK
Sbjct: 901  ADKSTSTSDPVIEDDHVQVLVLKSKNLVGVTMTNCGITDLVLKDCPKMMFIHATRCRVLK 960

Query: 886  HLKVENAPIVNRFDYAQCKKLNMDQVLDQILRMPPERNRIIYLRPMQQVDTLTLEQKLFS 945
            HLKVENAPIVNRFDYAQCKKLNMDQVLDQILRMPPERNRIIYLRPMQQVDTLTLEQKLFS
Sbjct: 961  HLKVENAPIVNRFDYAQCKKLNMDQVLDQILRMPPERNRIIYLRPMQQVDTLTLEQKLFS 1020

Query: 946  GPYPYHICIIHEFSNPPNVRNKVRIRSWMDTIANINQELIKYEFFPEATRSEEDLKKYPK 1005
            GPYPYHICIIHEFSNPPNVRNKVRIRSWMDTIANINQELIKYEFFPEATRSEEDLKKYPK
Sbjct: 1021 GPYPYHICIIHEFSNPPNVRNKVRIRSWMDTIANINQELIKYEFFPEATRSEEDLKKYPK 1080

Query: 1006 YPWGREIYTLEGVVDGAPYSMISDFPWLRSLRAAEPNSFARYDFEDDEESTIYAPRRKGQ 1065
            YPWGREIYTLEGVVDGAPYSMISDFPWLRSLRAAEPNSFARYDFEDDEESTIYAPRRKGQ
Sbjct: 1081 YPWGREIYTLEGVVDGAPYSMISDFPWLRSLRAAEPNSFARYDFEDDEESTIYAPRRKGQ 1140

Query: 1066 LSADICMETIGEEISEMRQMKKGVFQRVVAIFIHYCDVNGEPVEDDYI 1113
            LSADICMETIGEEISEMRQMKKGVFQRVVAIFIHYCDVNGEPVEDDYI
Sbjct: 1141 LSADICMETIGEEISEMRQMKKGVFQRVVAIFIHYCDVNGEPVEDDYI 1188


>gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens]
          Length = 1301

 Score = 57.4 bits (137), Expect = 7e-08
 Identities = 66/328 (20%), Positives = 121/328 (36%), Gaps = 7/328 (2%)

Query: 478 AGTGIGVSSALVSNQNSNNDDNNAQNNNANIHDNNHHHPDDSDEENDFRQDLQPGEQQFA 537
           +G G   SS   S+ +SN+ D++  +++ +   N+    D SD ++    D    +   +
Sbjct: 542 SGKGKSDSSDSDSSDSSNSSDSSDSSDSDSSDSNSSSDSDSSDSDSSDSSDSDSSDSSNS 601

Query: 538 ADALNEMEDIVQED----GEVVAESGNNTPAHSQAIIPVDVDEEQAGPSGLQRVVKPTSI 593
           +D+ +  +     D     +  ++S  +    S +    D  +  +  S        +S 
Sbjct: 602 SDSSDSSDSSDSSDSSDSSDSKSDSSKSESDSSDSDSKSDSSDSNSSDSSDNSDSSDSSN 661

Query: 594 TVHDSESDDEEDSLELQEVWIPKNGT-RRYSEREEKTGESVQSRELSVSGKGKTPLRKRY 652
           + + S+S D  DS +        N +    S     + ES  S + S S    +      
Sbjct: 662 SSNSSDSSDSSDSSDSSSSSDSSNSSDSSDSSDSSNSSESSDSSDSSDSDSSDSSDSSNS 721

Query: 653 NSHQMGQSKQFPLEESSCEKGCQVTSEQIKADMKAARDIPEKKKNKDVYPSCSSTTASTV 712
           NS     S      +SS       +S+   ++   + D  +   + D   S  S+ +S  
Sbjct: 722 NSSDSDSSNSSDSSDSSNSSDSSDSSD--SSNSSDSSDSSDSSNSSDSSDSSDSSDSSDS 779

Query: 713 GNSSSHNTASQSPDFVRTVNSGGSSEPSPTEVDVSRQCACSPGGSEDSEAMEEGDAESSV 772
            NSS  N +S S D   + NS  SS  S +        + S   S+ S + +  D+ +S 
Sbjct: 780 SNSSDSNDSSNSSDSSDSSNSSDSSNSSDSSDSSDSSDSDSSNSSDSSNSSDSSDSSNSS 839

Query: 773 CPRCCCHRPQESQRRTSRCSDEERPSTS 800
                      S   +S  SD    S S
Sbjct: 840 DSSDSSDSSDGSDSDSSNRSDSSNSSDS 867



 Score = 53.5 bits (127), Expect = 1e-06
 Identities = 64/360 (17%), Positives = 135/360 (37%), Gaps = 11/360 (3%)

Query: 485  SSALVSNQNSNNDDNNAQNNNANIHDNNHHHPDDSDEENDFRQDLQPGEQQFAADALNEM 544
            S++  S+++SN+ DN+  ++++N  D++      +  ++    D         +++ +  
Sbjct: 918  SNSSDSSESSNSSDNSNSSDSSNSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSNSSDSS 977

Query: 545  EDIVQEDGEVVAESGNNTPAHSQAIIPVDVDEEQAGPSGLQRVVKPTSITVHDSESDDEE 604
            +     D    ++S +++ +   +      D   +  S        +S + + S+S D  
Sbjct: 978  DSSNSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSS 1037

Query: 605  DSLELQEVWIPKNGTRRYSEREEKTGESVQSRELSVSGKGKTPLRKRYNSHQMGQSKQFP 664
            DS +  +     +     S     + +S  S + S S           +S     S    
Sbjct: 1038 DSSDSSD-----SSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSESSDSSDSSN 1092

Query: 665  LEESSCEKGCQVTSEQIKADMKAARDIPEKKKNKDVYPSCSSTTASTVGNSSSHNTASQS 724
              +SS       +S+   +D   + D  +   + D   S  S+ +S   NSS  + +S+S
Sbjct: 1093 SSDSSDSSDSSDSSD--SSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSSDSSES 1150

Query: 725  PDFVRTVNSGGSSEPS----PTEVDVSRQCACSPGGSEDSEAMEEGDAESSVCPRCCCHR 780
             D   + +S  SS+ S     ++   S   + S   S+ S++ +  D+  S         
Sbjct: 1151 SDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDS 1210

Query: 781  PQESQRRTSRCSDEERPSTSRACVVNGPDEVAKTKPRHAMKRKRTADKSTSTSDPVIEDD 840
               S    S  S +   S+      +  D    +   ++     ++D S STSD   E D
Sbjct: 1211 SDSSDSSDSSDSSDSSDSSDSNESSDSSDSSDSSDSSNSSDSSDSSDSSDSTSDSNDESD 1270



 Score = 51.6 bits (122), Expect = 4e-06
 Identities = 66/357 (18%), Positives = 130/357 (36%), Gaps = 14/357 (3%)

Query: 490  SNQNSNNDDNNAQNNNA---NIHDNNHHHPDDSDEENDFRQDLQPGEQQFAADALNEMED 546
            SN++SN+ D++  +N++   +   +N     DS   +D  +     +   ++D+ N  + 
Sbjct: 885  SNESSNSSDSSDSSNSSDSDSSDSSNSSDSSDSSNSSDSSESSNSSDNSNSSDSSNSSDS 944

Query: 547  IVQEDGEVVAESGNNTPAHSQAIIPVDVDEEQAGPSGLQRVVKPTSITVHDSESDDEEDS 606
                D    ++S N++ + + +    D  +  +  S        +S +   S+S D  DS
Sbjct: 945  SDSSDSSNSSDSSNSSDSSNSS----DSSDSNSSDSSDSSNSSDSSDSSDSSDSSDSSDS 1000

Query: 607  LELQEVWIPKNGTRRYSEREEKTGESVQSRELSVSGKGKTPLRKRYNSHQMGQSKQFPLE 666
                +     +     S     + +S  S + S S           +S     S      
Sbjct: 1001 SNSSD-----SSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSS 1055

Query: 667  ESSCEKGCQVTSEQI-KADMKAARDIPEKKKNKDVYPSCSSTTASTVGNSSSHNTASQSP 725
             SS       +S+    +D   + D  E   + D   S  S+ +S   +SS  + +S S 
Sbjct: 1056 NSSDSSDSSDSSDSSDSSDSSDSSDSSESSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSS 1115

Query: 726  DFVRTVNSGGSSEPS-PTEVDVSRQCACSPGGSEDSEAMEEGDAESSVCPRCCCHRPQES 784
            D   + NS  SS+ S  ++   S   + S   SE S++ +  D+  S            S
Sbjct: 1116 DSSDSSNSSDSSDSSDSSDSSDSSNSSDSSDSSESSDSSDSSDSSDSSDSSDSSDSSDSS 1175

Query: 785  QRRTSRCSDEERPSTSRACVVNGPDEVAKTKPRHAMKRKRTADKSTSTSDPVIEDDH 841
                S  S +   S+  +   +  D    +    +     ++D S S+      D +
Sbjct: 1176 DSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSN 1232



 Score = 47.8 bits (112), Expect = 6e-05
 Identities = 52/285 (18%), Positives = 108/285 (37%), Gaps = 5/285 (1%)

Query: 485  SSALVSNQNSNNDDNNAQNNNANIHDNNHHHPDDSD--EENDFRQDLQPGEQQFAADALN 542
            SS    + NS++  N++ ++N++   ++    D SD  + +D        +   ++D+ +
Sbjct: 1009 SSDSSDSSNSSDSSNSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSD 1068

Query: 543  EMEDIVQEDGEVVAESGNNTPAHSQAIIPVDVDEEQAGPSGLQRVVKPTSITVHDSESDD 602
              +     D    +ES +++ + + +      D   +  S        +S + + S+S D
Sbjct: 1069 SSDSSDSSDSSDSSESSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSD 1128

Query: 603  EEDSLELQEVWIPKNGTRRYSEREEKTGESVQSRELSVSGKGKTPLRKRYNSHQMGQSKQ 662
              DS +  +     +     S     + +S  S + S S           +S+    S  
Sbjct: 1129 SSDSSDSSDS--SNSSDSSDSSESSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDS 1186

Query: 663  FPLEESSCEKGCQVTSEQI-KADMKAARDIPEKKKNKDVYPSCSSTTASTVGNSSSHNTA 721
                +SS       +S+    +D   + D  +   + D   S  S  +S   +SS  + +
Sbjct: 1187 SDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSNESSDSSDSSDSSDS 1246

Query: 722  SQSPDFVRTVNSGGSSEPSPTEVDVSRQCACSPGGSEDSEAMEEG 766
            S S D   + +S  S+  S  E D   +         DS++  EG
Sbjct: 1247 SNSSDSSDSSDSSDSTSDSNDESDSQSKSGNGNNNGSDSDSDSEG 1291



 Score = 47.4 bits (111), Expect = 8e-05
 Identities = 54/294 (18%), Positives = 106/294 (36%), Gaps = 14/294 (4%)

Query: 491 NQNSNNDDNNAQNNNANIHDNNHHHPDDSDEENDF--RQDLQPGEQQFAADALNEMEDIV 548
           N N+ NDDN+  ++     D++     DS   +D     D    +   ++D+ +   D  
Sbjct: 529 NGNNGNDDNDKSDSGKGKSDSSDSDSSDSSNSSDSSDSSDSDSSDSNSSSDSDSSDSDSS 588

Query: 549 QEDGEVVAESGNNTPAHSQAIIPVDVDEEQAGPSGLQRVVKPTSITVHDSESDDEE---- 604
                  ++S N++ +   +      D   +  S        +  +  DS+SD  +    
Sbjct: 589 DSSDSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSKSDSSKSESDSSDSDSKSDSSDSNSS 648

Query: 605 DSLELQEVWIPKNGTRRYSEREEKTGESVQSRELSVSGKGKTPLRKRYNSHQMGQSKQFP 664
           DS +  +     N +      +        S   S +    +      NS +   S    
Sbjct: 649 DSSDNSDSSDSSNSSNSSDSSDSSDSSDSSSSSDSSNSSDSSDSSDSSNSSESSDSSDSS 708

Query: 665 LEESSCEKGCQVTSEQIKADMKAARDIPEKKKNKDVYPSCSSTTASTVGNSSSHNTASQS 724
             +SS +      S    +D   + D  +   + D   S  S+ +S   +SS  + +S S
Sbjct: 709 DSDSS-DSSDSSNSNSSDSDSSNSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSNSSDS 767

Query: 725 PDFVRTVNSGGSSEPS-------PTEVDVSRQCACSPGGSEDSEAMEEGDAESS 771
            D   + +S  SS  S        ++   S   + S   S+ S++ +  D++SS
Sbjct: 768 SDSSDSSDSSDSSNSSDSNDSSNSSDSSDSSNSSDSSNSSDSSDSSDSSDSDSS 821



 Score = 47.0 bits (110), Expect = 1e-04
 Identities = 56/279 (20%), Positives = 106/279 (37%), Gaps = 29/279 (10%)

Query: 493 NSNNDDNNAQNNNANIHDNNHHHPDDSDEENDFRQDLQPGEQQFAADALNEMEDIVQEDG 552
           N N+D N+  +NN++   +  ++ D+S ++N    D +  E     D  +   D    D 
Sbjct: 472 NGNDDANSESDNNSSSRGDASYNSDES-KDNGNGSDSKGAED----DDSDSTSDTNNSDS 526

Query: 553 EVVAESGNNTPAHSQAIIPVDVDEEQAGPSGLQRVVKPTSITVHDSESDDEEDSLELQEV 612
                +GN+           D D+  +G          +S + + S+S D  DS      
Sbjct: 527 NGNGNNGND-----------DNDKSDSGKGKSDSSDSDSSDSSNSSDSSDSSDS------ 569

Query: 613 WIPKNGTRRYSEREEKTGESVQSRELSVSGKGKTPLRKRYNSHQMGQSKQFPLEESSCEK 672
               + +   S+ +    +S  S +   S    +      +S     S      +SS  K
Sbjct: 570 --DSSDSNSSSDSDSSDSDSSDSSDSDSSDSSNS----SDSSDSSDSSDSSDSSDSSDSK 623

Query: 673 GCQVTSEQIKADMKAARDIPEKKKNKDVYPSCSSTTASTVGNSSSHNTASQSPDFVRTVN 732
                SE   +D  +  D  +   + D   +  S+ +S   NSS  + +S S D   + +
Sbjct: 624 SDSSKSESDSSDSDSKSDSSD-SNSSDSSDNSDSSDSSNSSNSSDSSDSSDSSDSSSSSD 682

Query: 733 SGGSSEPSPTEVDVSRQCACSPGGSEDSEAMEEGDAESS 771
           S  SS+ S +    +   +     S DS++ +  D+ +S
Sbjct: 683 SSNSSDSSDSSDSSNSSESSDSSDSSDSDSSDSSDSSNS 721



 Score = 47.0 bits (110), Expect = 1e-04
 Identities = 54/294 (18%), Positives = 113/294 (38%), Gaps = 17/294 (5%)

Query: 479 GTGIGVSSALVSNQNSNNDDNNAQNNNANIHDNNHHHPDDSDEENDFRQDLQPGEQQFAA 538
           G G     A   + +S +D NN+ +N       N ++ +D ++++D  +         ++
Sbjct: 502 GNGSDSKGAEDDDSDSTSDTNNSDSN------GNGNNGNDDNDKSDSGKGKSDSSDSDSS 555

Query: 539 DALNEMEDIVQEDGEVVAESGNNTPAHSQAIIPVDVDEEQAGPSGLQRVVKPTSITVHDS 598
           D+ N  +     D +  ++S +++ + S      D  +  +  S        +S +   S
Sbjct: 556 DSSNSSDSSDSSDSD-SSDSNSSSDSDSSDSDSSDSSDSDSSDSSNSSDSSDSSDSSDSS 614

Query: 599 ESDDEEDSLELQEVWIPKNGTRRYSEREEKTGESVQSRELSVSGKGKTPLRKRYNSHQMG 658
           +S D  DS          + ++  S+  +   +S  S   S      +      NS    
Sbjct: 615 DSSDSSDS--------KSDSSKSESDSSDSDSKSDSSDSNSSDSSDNSDSSDSSNSSNSS 666

Query: 659 QSKQFPLEESSCEKGCQVTSEQIKADMKAARDIPEKKKNKDVYPSCSSTTASTVGNSSSH 718
            S     + S        ++    +D   + +  E   + D   S SS ++ +  ++SS 
Sbjct: 667 DSSD-SSDSSDSSSSSDSSNSSDSSDSSDSSNSSESSDSSDSSDSDSSDSSDSSNSNSSD 725

Query: 719 NTASQSPDFVRTVNSGGSSEPS-PTEVDVSRQCACSPGGSEDSEAMEEGDAESS 771
           + +S S D   + NS  SS+ S  +    S   + S   S+ S++ +  D+  S
Sbjct: 726 SDSSNSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSSDS 779



 Score = 42.4 bits (98), Expect = 0.002
 Identities = 66/340 (19%), Positives = 115/340 (33%), Gaps = 32/340 (9%)

Query: 494 SNNDDNNAQNNNANIHDNNHHHPDDSDEENDFRQDLQPGEQQFAADALNEMEDIVQEDGE 553
           S N D +  N N +  D+     DDSD  +D       G      D  N+  D  +   +
Sbjct: 492 SYNSDESKDNGNGS--DSKGAEDDDSDSTSDTNNSDSNGNGNNGNDD-NDKSDSGKGKSD 548

Query: 554 VVAESGNNTPAHSQAIIPVDVDEEQAGPSGLQRVVKPTSITVHDSESDDEEDSLELQEVW 613
                 +++   S +    D D   +  S        +     DS+S D  DS       
Sbjct: 549 SSDSDSSDSSNSSDSSDSSDSDSSDSNSS--------SDSDSSDSDSSDSSDS------- 593

Query: 614 IPKNGTRRYSEREEKTGESVQSRELSVSGKGKTPLRKRYNSHQMGQSKQFPLEESSCEKG 673
              +     S     + +S  S + S S   K+   K  +      SK    + +S +  
Sbjct: 594 --DSSDSSNSSDSSDSSDSSDSSDSSDSSDSKSDSSKSESDSSDSDSKSDSSDSNSSD-- 649

Query: 674 CQVTSEQIKADMKAARDIPEKKKNKDVYPSCSSTTASTVGNSSSHNTASQSPDFVRTVNS 733
                    +D   + D      + D   S  S+ +S+  +SS+ + +S S D   +  S
Sbjct: 650 --------SSDNSDSSDSSNSSNSSDSSDSSDSSDSSSSSDSSNSSDSSDSSDSSNSSES 701

Query: 734 GGSSEPSPTEVDVSRQCACSPGGSEDSEAMEEGDAESSVCPRCCCHRPQESQRRTSRCSD 793
             SS+ S  + D S     S   S DS++    D+  S            S    S  S 
Sbjct: 702 SDSSDSS--DSDSSDSSDSSNSNSSDSDSSNSSDSSDSSNSSDSSDSSDSSNSSDSSDSS 759

Query: 794 EERPSTSRACVVNGPDEVAKTKPRHAMKRKRTADKSTSTS 833
           +   S+  +   +  D    +    +     ++D S S++
Sbjct: 760 DSSNSSDSSDSSDSSDSSDSSNSSDSNDSSNSSDSSDSSN 799


>gi|148596949 nucleolar and coiled-body phosphoprotein 1 [Homo
           sapiens]
          Length = 699

 Score = 48.5 bits (114), Expect = 3e-05
 Identities = 86/412 (20%), Positives = 150/412 (36%), Gaps = 81/412 (19%)

Query: 506 ANIHDNNHHHPDDSDEENDFRQDLQPGEQQFAADALNEMEDIVQEDGEVVAESGNNTPAH 565
           A+   ++    DD DEE+  +Q +Q G +  A  A    +     D +  + S +  P +
Sbjct: 123 ASESSSSEESSDDDDEEDQKKQPVQKGVKPQAKAAKAPPKKAKSSDSDSDSSSEDEPPKN 182

Query: 566 SQ-AIIPVDVDEEQAGPSGLQRVV------KPTSITVHDSESDDEEDSLELQEVWIPK-- 616
            +  I PV V  +   P    R        K  S +   S S   +DS E +    PK  
Sbjct: 183 QKPKITPVTVKAQTKAPPKPARAAPKIANGKAASSSSSSSSSSSSDDSEEEKAAATPKKT 242

Query: 617 ----------------NGTRRYSEREEKTGESVQSRELSVSGK----------GKTPLRK 650
                             TR+ S  E+ + +  + ++  +  K             P +K
Sbjct: 243 VPKKQVVAKAPVKAATTPTRKSSSSEDSSSDEEEEQKKPMKNKPGPYSSVPPPSAPPPKK 302

Query: 651 RYNSH--QMGQSKQFPLE--ESSCEKGCQVTSEQIKADMKAARDIPEKKKNKDVYPSCSS 706
              +   +    KQ P+E  E S ++    + E+ K   KA       K      P+  +
Sbjct: 303 SLGTQPPKKAVEKQQPVESSEDSSDESDSSSEEEKKPPTKAV----VSKATTKPPPAKKA 358

Query: 707 TTASTVGNSSSHNTASQSPDFVRTVNSGGSSEPSPTEVDVSRQCACSP----GGSE---- 758
             +S+  + S  +   ++P          S++P+ T    + + A +P    GG +    
Sbjct: 359 AESSSDSSDSDSSEDDEAPSKPAGTTKNSSNKPAVTTKSPAVKPAAAPKQPVGGGQKLLT 418

Query: 759 ---DSEAMEEGDAES----------SVCPRCCC---------HRPQESQRRT----SRCS 792
              DS + EE  + S          +  P+              PQ S+  +    S  S
Sbjct: 419 RKADSSSSEEESSSSEEEKTKKMVATTKPKATAKAALSLPAKQAPQGSRDSSSDSDSSSS 478

Query: 793 DEERPSTSRACVVNGPDEV----AKTKPRHAMKRKRTADKSTSTSDPVIEDD 840
           +EE   TS++ V   P +V    A +KP  A K K  +  S+S+ D   E++
Sbjct: 479 EEEEEKTSKSAVKKKPQKVAGGAAPSKPASAKKGKAESSNSSSSDDSSEEEE 530



 Score = 40.4 bits (93), Expect = 0.009
 Identities = 53/243 (21%), Positives = 92/243 (37%), Gaps = 23/243 (9%)

Query: 598 SESDDEEDSLELQEVWIPKNGTRRYSEREEKTGESVQSRELS-----VSGKGKTPLRKRY 652
           S+S D + S + +    P   T+  S +   T +S   +  +     V G  K   RK  
Sbjct: 363 SDSSDSDSSEDDEAPSKPAGTTKNSSNKPAVTTKSPAVKPAAAPKQPVGGGQKLLTRKAD 422

Query: 653 NSHQMGQSKQFPLEESSCEKGCQVTSEQIKADMKAARDIPEKKK---NKDVYPSCSSTTA 709
           +S    +S     EE   +K   V + + KA  KAA  +P K+    ++D      S+++
Sbjct: 423 SSSSEEESSSS--EEEKTKK--MVATTKPKATAKAALSLPAKQAPQGSRDSSSDSDSSSS 478

Query: 710 STVGNSSSHNTASQSPDFVRTVNSGGSSEPSPTEVDVSRQCACSPGGSEDSEAMEEGDAE 769
                 +S +   + P  V    +GG++   P      +  + +   S+DS   EE   +
Sbjct: 479 EEEEEKTSKSAVKKKPQKV----AGGAAPSKPASAKKGKAESSNSSSSDDSSEEEEEKLK 534

Query: 770 SSVCPRCCCHRPQESQRRTSR-------CSDEERPSTSRACVVNGPDEVAKTKPRHAMKR 822
               PR    +   +   T++         +EE      A VV+    + K K   A K 
Sbjct: 535 GKGSPRPQAPKANGTSALTAQNGKAAKNSEEEEEEKKKAAVVVSKSGSLKKRKQNEAAKE 594

Query: 823 KRT 825
             T
Sbjct: 595 AET 597



 Score = 37.7 bits (86), Expect = 0.061
 Identities = 53/253 (20%), Positives = 91/253 (35%), Gaps = 49/253 (19%)

Query: 598 SESDDEEDSLELQEVWIPKNGTRRYSEREEKTGESVQSRELSVSGKGKTPLRKRYNSHQM 657
           + S D EDS E               E EE  G   +   +     G  P +    + + 
Sbjct: 82  ASSSDSEDSSE---------------EEEEVQGPPAKKAAVPAKRVGLPPGKAAAKASES 126

Query: 658 GQSKQFPLEESSCEKGCQVTSEQIKADMKAARDIPEKKKNKDVYPSCSSTTASTVGNSSS 717
             S++   ++   ++  Q   + +K   KAA+  P+K K+ D               S S
Sbjct: 127 SSSEESSDDDDEEDQKKQPVQKGVKPQAKAAKAPPKKAKSSD---------------SDS 171

Query: 718 HNTASQSPDFVRTVNSGGSSEPSPTEVDVSRQCACSPGGSEDSEAMEEGDAESSVCPRCC 777
            +++   P          + +P  T V V  Q    P  +  +  +  G A SS      
Sbjct: 172 DSSSEDEPP--------KNQKPKITPVTVKAQTKAPPKPARAAPKIANGKAASS------ 217

Query: 778 CHRPQESQRRTSRCSDEERPSTSRACVVNGPDEVAKTKPRHAMKRKRTADKSTSTSDPVI 837
                 S   +S  S+EE+ + +    V     VAK   + A    R   KS+S+ D   
Sbjct: 218 --SSSSSSSSSSDDSEEEKAAATPKKTVPKKQVVAKAPVKAATTPTR---KSSSSEDSSS 272

Query: 838 EDDHVQVLVLKSK 850
           +++  Q   +K+K
Sbjct: 273 DEEEEQKKPMKNK 285


>gi|4504487 histidine rich calcium binding protein precursor [Homo
           sapiens]
          Length = 699

 Score = 41.2 bits (95), Expect = 0.006
 Identities = 37/154 (24%), Positives = 58/154 (37%), Gaps = 30/154 (19%)

Query: 490 SNQNSNNDDNNAQNNNANIHDNNHHHP-------------DDSDEENDFRQDLQPGEQQF 536
           S++ S+ D+        +I + +HH P             DDS+EE +  +D  PG    
Sbjct: 440 SHRQSHQDEETGHGQRGSIKEMSHHPPGHTVVKDRSHLRKDDSEEEKEKEED--PGS--- 494

Query: 537 AADALNEMEDIVQEDGEVVAESGNNTPAHSQAIIPVDVDEEQAGPSGLQRVVKPTSITVH 596
                +E +D   E GE     G+      +       DEE+     L +  +       
Sbjct: 495 -----HEEDDESSEQGEKGTHHGSRDQEDEE-------DEEEGHGLSLNQEEEEEEDKEE 542

Query: 597 DSESDDEEDSLELQEVWIPKNGTRRYSEREEKTG 630
           + E +DEE   E  EV  P +      E EE+ G
Sbjct: 543 EEEEEDEERREERAEVGAPLSPDHSEEEEEEEEG 576



 Score = 31.6 bits (70), Expect = 4.4
 Identities = 62/311 (19%), Positives = 114/311 (36%), Gaps = 33/311 (10%)

Query: 491 NQNSNNDDNNAQNNNANIHDNNHHHPDDSDEENDFRQDLQPGE-QQFAADALNEMEDIVQ 549
           +Q+   ++  A +   + H  +H H    DEE D  +D+      Q      + + D  +
Sbjct: 321 HQDHRKEEVEAVSGEHHHHVPDHRHQGHRDEEED--EDVSTERWHQGPQHVHHGLVDEEE 378

Query: 550 EDGEVVAESGNNTPAHSQAIIPVDVDEEQAGPSGLQRVVKPTSITVHDSESDDEEDSLEL 609
           E+ E+  + G+   +H       D ++ Q       +   P          +DEE S EL
Sbjct: 379 EEEEITVQFGHYVASHQPRGHKSDEEDFQ----DEYKTEVPHHHHHRVPREEDEEVSAEL 434

Query: 610 QEVWIPKNGTRRYSEREEKTGESVQS--RELSVSGKGKTPLRKRYNSHQMGQSKQFPLEE 667
                 +  + R S ++E+TG   +   +E+S    G T ++ R +  +    ++   EE
Sbjct: 435 GH----QAPSHRQSHQDEETGHGQRGSIKEMSHHPPGHTVVKDRSHLRKDDSEEEKEKEE 490

Query: 668 --SSCEKGCQVTSEQIKADMKAARDIPEKKKNKDVYPSCSSTTASTVGNSSSHNTASQSP 725
              S E+  + + +  K     +RD  +++  ++             G+  S N   +  
Sbjct: 491 DPGSHEEDDESSEQGEKGTHHGSRDQEDEEDEEE-------------GHGLSLNQEEEEE 537

Query: 726 DFVRTVNSGGSSEPSPTEVDVSRQCACSPGGSEDSEAMEEGDAESSVCPR-CCCHRPQES 784
           +           E      +V      SP  SE+ E  EEG  E    PR      P + 
Sbjct: 538 EDKEEEEEEEDEERREERAEVG--APLSPDHSEEEEEEEEGLEEDE--PRFTIIPNPLDR 593

Query: 785 QRRTSRCSDEE 795
           +      S EE
Sbjct: 594 REEAGGASSEE 604



 Score = 30.4 bits (67), Expect = 9.7
 Identities = 42/232 (18%), Positives = 83/232 (35%), Gaps = 31/232 (13%)

Query: 509 HDNNHHHPDDSDEENDFRQDLQPGEQQFAADALNEMEDIVQEDGEVVAESGNNTPAHSQA 568
           H    H  D+ D +++++ ++ P                 +ED EV AE G+  P+H Q+
Sbjct: 394 HQPRGHKSDEEDFQDEYKTEV-PHHHHHRVPR--------EEDEEVSAELGHQAPSHRQS 444

Query: 569 IIPVDVDEEQAG--------PSGLQRVVKPTSITVHDSESDDE--------EDSLELQEV 612
               +    Q G        P G   V   + +   DSE + E        E+  E  E 
Sbjct: 445 HQDEETGHGQRGSIKEMSHHPPGHTVVKDRSHLRKDDSEEEKEKEEDPGSHEEDDESSEQ 504

Query: 613 WIPKNGTRRYSEREEKTGESVQSRELSVSGKGKTPLRKRYNSHQMGQSKQFPLEESSCEK 672
              + GT   S  +E   +  +   LS++ + +    K     +  + ++    E   E 
Sbjct: 505 --GEKGTHHGSRDQEDEEDEEEGHGLSLNQEEEEEEDKEEEEEEEDEERR----EERAEV 558

Query: 673 GCQVTSEQIKADMKAARDIPEKKKNKDVYPSCSSTTASTVGNSSSHNTASQS 724
           G  ++ +  + + +    + E +    + P+         G SS   +   +
Sbjct: 559 GAPLSPDHSEEEEEEEEGLEEDEPRFTIIPNPLDRREEAGGASSEEESGEDT 610


>gi|28372531 protein phosphatase 4, regulatory subunit 2 [Homo
           sapiens]
          Length = 417

 Score = 40.4 bits (93), Expect = 0.009
 Identities = 50/223 (22%), Positives = 83/223 (37%), Gaps = 29/223 (13%)

Query: 487 ALVSNQNSNNDDNNAQNNNANIHDNNH-HHPDDSDEENDFR-----QDLQPGEQQFAADA 540
           +L +   +N    +  +  AN+  N   +H D S  E++       ++  P E    A+ 
Sbjct: 183 SLSAPMTTNGLPESTDSKEANLQQNEEKNHSDSSTSESEVSSVSPLKNKHPDEDAVEAEG 242

Query: 541 LNEMEDIVQEDGEVVAESGNNTPAHSQAIIPVDVDEEQAGPSGLQRVVKPTSITVHDSES 600
                    ++GEV   +   T   S  I  V V E +A  S   +         H +E 
Sbjct: 243 HEVKRLRFDKEGEVRETASQTT---SSEISSVMVGETEASSSSQDKDKDSRCTRQHCTEE 299

Query: 601 DDEEDSLELQEVWI------------PKNGTRRYSEREEKTGESVQSRELSVSGKGKTPL 648
           D+EED  E +E ++             K      +  EE + E+ Q  E  VS   K  L
Sbjct: 300 DEEEDEEEEEESFMTSREMIPERKNQEKESDDALTVNEETSEENNQMEESDVSQAEKDLL 359

Query: 649 RKRYNSHQMGQSKQFPLEESSCEKGCQVTSEQIKADMKAARDI 691
                 H  G   + P+  SS +  C+ T E + ++     +I
Sbjct: 360 ------HSEGSENEGPVSSSSSD--CRETEELVGSNSSKTGEI 394


>gi|62244004 modulator of estrogen induced transcription isoform b
           [Homo sapiens]
          Length = 1016

 Score = 39.7 bits (91), Expect = 0.016
 Identities = 92/440 (20%), Positives = 163/440 (37%), Gaps = 85/440 (19%)

Query: 458 ISLDQMFREPPKGCARVGLS---AGTGIGVSSALVSNQNSNNDDNNAQNNNANIHDNNHH 514
           +S D   ++P KG  +   +   +G       A + +    N + + Q+ N  + D+   
Sbjct: 70  VSTDTPNKKPTKGKGKKHEADELSGDASVEDDAFIKDCELENQEAHEQDGNDELKDSEEF 129

Query: 515 HPDDSDEENDFRQDLQPGEQQFAADALNE---MEDIVQED---GEVVAESGNNTPAHSQA 568
              +++EEN   ++L   E+   A  L E   +EDI +ED    E+ A+ G +       
Sbjct: 130 --GENEEENVHSKELLSAEENKRAHELIEAEGIEDIEKEDIESQEIEAQEGED----DTF 183

Query: 569 IIPVDVDEEQAGPSGLQRVVKPTS-------ITVHDSESD----------------DEED 605
           +   D +EE+    G       T+        TV ++E D                D +D
Sbjct: 184 LTAQDGEEEENEKEGSLAEADHTAHEEMEAHTTVKEAEDDNISVTIQAEDAITLDFDGDD 243

Query: 606 SLEL--------QEVWIPKNGTRRYSEREEKTGESVQSRELSVSGKGKT-----PLRKRY 652
            LE          E   PK+G    ++  EK  +  +       GK +      P+ K  
Sbjct: 244 LLETGKNVKITDSEASKPKDGQDAIAQSPEKESKDYEMNANHKDGKKEDCVKGDPVEKEA 303

Query: 653 NSHQMGQSKQFPLEESSCEKGCQVT--SEQIKADMKAARDIPEKKKNKDVYPSCSSTTAS 710
                 +++    E+ + +KG   T  S Q K+  K ++D   K  +KD   S SST+ S
Sbjct: 304 RESSK-KAESGDKEKDTLKKGPSSTGASGQAKSSSKESKD--SKTSSKDDKGSTSSTSGS 360

Query: 711 TVGNS-----SSHNTASQSPDFVRTVNSGGSSEPSPTEVDVSRQCACSPGGSEDSEAMEE 765
           +  ++     S  ++ +++ D        G    +    +     A SPG          
Sbjct: 361 SGSSTKNIWVSGLSSNTKAADLKNLFGKYGKVLSAKVVTN-----ARSPGAKCYGIVTMS 415

Query: 766 GDAESSVCPRCCCH----------------RPQESQRRTSRCSDEERPSTSRACVVNGPD 809
              E S   RC  H                +   S++   + +DE+  S S     N  D
Sbjct: 416 SSTEVS---RCIAHLHRTELHGQLISVEKVKGDPSKKEMKKENDEKSSSRSSGDKKNTSD 472

Query: 810 EVAKTKPRHAMKRKRTADKS 829
             +KT+     + KR+++KS
Sbjct: 473 RSSKTQASVKKEEKRSSEKS 492


>gi|207113164 Treacher Collins-Franceschetti syndrome 1 isoform f
           [Homo sapiens]
          Length = 1412

 Score = 38.5 bits (88), Expect = 0.036
 Identities = 48/174 (27%), Positives = 71/174 (40%), Gaps = 16/174 (9%)

Query: 597 DSESDDEEDSLELQEVWIPKNGTRRYSEREEKTGESVQSRELSVSGKGKTPLRKRYNSHQ 656
           DSES  EE S +  +  +P   T     +E+  G  +Q++  S   KG  P +    + Q
Sbjct: 467 DSESSSEESS-DSSDGEVP---TAVAPAQEKSLGNILQAKPTSSPAKGP-PQKAGPVAVQ 521

Query: 657 MGQSKQFPLEESSCEKGCQVTSEQIKADMKAARDIPEKK-KNKDVYPSCSSTTASTVGNS 715
           +   K     ESS E      SE+  A M AA+  P  K       P  ++TTAS     
Sbjct: 522 VKAEKPMDNSESSEESSDSADSEEAPAAMTAAQAKPALKIPQTKACPKKTNTTAS--AKV 579

Query: 716 SSHNTASQSPDFVRTVNSGGSSEPSPTEVDVSRQCACSPGGSEDSEAMEEGDAE 769
           +     +Q+P    T  S   S P+            +   +EDS + EE D+E
Sbjct: 580 APVRVGTQAPRKAGTATSPAGSSPA--------VAGGTQRPAEDSSSSEESDSE 625


>gi|207113162 Treacher Collins-Franceschetti syndrome 1 isoform e
           [Homo sapiens]
          Length = 1451

 Score = 38.5 bits (88), Expect = 0.036
 Identities = 48/174 (27%), Positives = 71/174 (40%), Gaps = 16/174 (9%)

Query: 597 DSESDDEEDSLELQEVWIPKNGTRRYSEREEKTGESVQSRELSVSGKGKTPLRKRYNSHQ 656
           DSES  EE S +  +  +P   T     +E+  G  +Q++  S   KG  P +    + Q
Sbjct: 544 DSESSSEESS-DSSDGEVP---TAVAPAQEKSLGNILQAKPTSSPAKGP-PQKAGPVAVQ 598

Query: 657 MGQSKQFPLEESSCEKGCQVTSEQIKADMKAARDIPEKK-KNKDVYPSCSSTTASTVGNS 715
           +   K     ESS E      SE+  A M AA+  P  K       P  ++TTAS     
Sbjct: 599 VKAEKPMDNSESSEESSDSADSEEAPAAMTAAQAKPALKIPQTKACPKKTNTTAS--AKV 656

Query: 716 SSHNTASQSPDFVRTVNSGGSSEPSPTEVDVSRQCACSPGGSEDSEAMEEGDAE 769
           +     +Q+P    T  S   S P+            +   +EDS + EE D+E
Sbjct: 657 APVRVGTQAPRKAGTATSPAGSSPA--------VAGGTQRPAEDSSSSEESDSE 702


>gi|207113160 Treacher Collins-Franceschetti syndrome 1 isoform d
           [Homo sapiens]
          Length = 1488

 Score = 38.5 bits (88), Expect = 0.036
 Identities = 48/174 (27%), Positives = 71/174 (40%), Gaps = 16/174 (9%)

Query: 597 DSESDDEEDSLELQEVWIPKNGTRRYSEREEKTGESVQSRELSVSGKGKTPLRKRYNSHQ 656
           DSES  EE S +  +  +P   T     +E+  G  +Q++  S   KG  P +    + Q
Sbjct: 544 DSESSSEESS-DSSDGEVP---TAVAPAQEKSLGNILQAKPTSSPAKGP-PQKAGPVAVQ 598

Query: 657 MGQSKQFPLEESSCEKGCQVTSEQIKADMKAARDIPEKK-KNKDVYPSCSSTTASTVGNS 715
           +   K     ESS E      SE+  A M AA+  P  K       P  ++TTAS     
Sbjct: 599 VKAEKPMDNSESSEESSDSADSEEAPAAMTAAQAKPALKIPQTKACPKKTNTTAS--AKV 656

Query: 716 SSHNTASQSPDFVRTVNSGGSSEPSPTEVDVSRQCACSPGGSEDSEAMEEGDAE 769
           +     +Q+P    T  S   S P+            +   +EDS + EE D+E
Sbjct: 657 APVRVGTQAPRKAGTATSPAGSSPA--------VAGGTQRPAEDSSSSEESDSE 702


>gi|57164975 Treacher Collins-Franceschetti syndrome 1 isoform b
           [Homo sapiens]
          Length = 1411

 Score = 38.5 bits (88), Expect = 0.036
 Identities = 48/174 (27%), Positives = 71/174 (40%), Gaps = 16/174 (9%)

Query: 597 DSESDDEEDSLELQEVWIPKNGTRRYSEREEKTGESVQSRELSVSGKGKTPLRKRYNSHQ 656
           DSES  EE S +  +  +P   T     +E+  G  +Q++  S   KG  P +    + Q
Sbjct: 467 DSESSSEESS-DSSDGEVP---TAVAPAQEKSLGNILQAKPTSSPAKGP-PQKAGPVAVQ 521

Query: 657 MGQSKQFPLEESSCEKGCQVTSEQIKADMKAARDIPEKK-KNKDVYPSCSSTTASTVGNS 715
           +   K     ESS E      SE+  A M AA+  P  K       P  ++TTAS     
Sbjct: 522 VKAEKPMDNSESSEESSDSADSEEAPAAMTAAQAKPALKIPQTKACPKKTNTTAS--AKV 579

Query: 716 SSHNTASQSPDFVRTVNSGGSSEPSPTEVDVSRQCACSPGGSEDSEAMEEGDAE 769
           +     +Q+P    T  S   S P+            +   +EDS + EE D+E
Sbjct: 580 APVRVGTQAPRKAGTATSPAGSSPA--------VAGGTQRPAEDSSSSEESDSE 625


>gi|57164977 Treacher Collins-Franceschetti syndrome 1 isoform a
           [Homo sapiens]
          Length = 1450

 Score = 38.5 bits (88), Expect = 0.036
 Identities = 48/174 (27%), Positives = 71/174 (40%), Gaps = 16/174 (9%)

Query: 597 DSESDDEEDSLELQEVWIPKNGTRRYSEREEKTGESVQSRELSVSGKGKTPLRKRYNSHQ 656
           DSES  EE S +  +  +P   T     +E+  G  +Q++  S   KG  P +    + Q
Sbjct: 544 DSESSSEESS-DSSDGEVP---TAVAPAQEKSLGNILQAKPTSSPAKGP-PQKAGPVAVQ 598

Query: 657 MGQSKQFPLEESSCEKGCQVTSEQIKADMKAARDIPEKK-KNKDVYPSCSSTTASTVGNS 715
           +   K     ESS E      SE+  A M AA+  P  K       P  ++TTAS     
Sbjct: 599 VKAEKPMDNSESSEESSDSADSEEAPAAMTAAQAKPALKIPQTKACPKKTNTTAS--AKV 656

Query: 716 SSHNTASQSPDFVRTVNSGGSSEPSPTEVDVSRQCACSPGGSEDSEAMEEGDAE 769
           +     +Q+P    T  S   S P+            +   +EDS + EE D+E
Sbjct: 657 APVRVGTQAPRKAGTATSPAGSSPA--------VAGGTQRPAEDSSSSEESDSE 702


>gi|57164979 Treacher Collins-Franceschetti syndrome 1 isoform c
           [Homo sapiens]
          Length = 958

 Score = 38.5 bits (88), Expect = 0.036
 Identities = 48/174 (27%), Positives = 71/174 (40%), Gaps = 16/174 (9%)

Query: 597 DSESDDEEDSLELQEVWIPKNGTRRYSEREEKTGESVQSRELSVSGKGKTPLRKRYNSHQ 656
           DSES  EE S +  +  +P   T     +E+  G  +Q++  S   KG  P +    + Q
Sbjct: 544 DSESSSEESS-DSSDGEVP---TAVAPAQEKSLGNILQAKPTSSPAKGP-PQKAGPVAVQ 598

Query: 657 MGQSKQFPLEESSCEKGCQVTSEQIKADMKAARDIPEKK-KNKDVYPSCSSTTASTVGNS 715
           +   K     ESS E      SE+  A M AA+  P  K       P  ++TTAS     
Sbjct: 599 VKAEKPMDNSESSEESSDSADSEEAPAAMTAAQAKPALKIPQTKACPKKTNTTAS--AKV 656

Query: 716 SSHNTASQSPDFVRTVNSGGSSEPSPTEVDVSRQCACSPGGSEDSEAMEEGDAE 769
           +     +Q+P    T  S   S P+            +   +EDS + EE D+E
Sbjct: 657 APVRVGTQAPRKAGTATSPAGSSPA--------VAGGTQRPAEDSSSSEESDSE 702


>gi|4758172 dentin matrix acidic phosphoprotein 1 isoform 1
           precursor [Homo sapiens]
          Length = 513

 Score = 38.1 bits (87), Expect = 0.047
 Identities = 80/384 (20%), Positives = 142/384 (36%), Gaps = 42/384 (10%)

Query: 517 DDSDEENDFRQDLQPGEQQFAADALNEMEDIVQEDGEVVAESGNNTPAHSQAIIPVDVDE 576
           +DSD+     ++  P  Q  A D  +E  ++  ED       G ++   S++      +E
Sbjct: 138 EDSDDTIQASEESAPQGQDSAQDTTSESRELDNEDRVDSKPEGGDSTQESES------EE 191

Query: 577 EQAGPSGLQRVVKPTSITVHDSESDDEEDSLELQEVWIPKNGTRRYSEREEKTGESVQSR 636
              G           S     SE DDE    +  E    + G  R +    K+ ES ++ 
Sbjct: 192 HWVGGGS-----DGESSHGDGSELDDEGMQSDDPESIRSERGNSRMNSAGMKSKESGENS 246

Query: 637 ELSVSGKGKTPLRKRYNSHQMGQSKQFPLEESSCEKGCQVTSEQIKADM---KAARDI-- 691
           E + +          + S ++ +  +   E+   E     T E++K+D      +RD   
Sbjct: 247 EQANTQDSGGSQLLEHPSRKIFRKSRISEEDDRSELDDNNTMEEVKSDSTENSNSRDTGL 306

Query: 692 ------------PEKKKNKDVYPSCS----STTASTVGNSSSHNTASQSPDFVRTVNSGG 735
                        + K+N     S +    S+ +S   N SS   +S+S + V + + G 
Sbjct: 307 SQPRRDSKGDSQEDSKENLSQEESQNVDGPSSESSQEANLSSQENSSESQEEVVSESRGD 366

Query: 736 SSEPSPTEV------DVSRQCACSPGGSEDSEAMEE-GDAESSVCPRCCCHRPQESQRRT 788
           + +P+ + V      D S + +        SE+ EE  D+ESS         P ES    
Sbjct: 367 NPDPTTSYVEDQEDSDSSEEDSSHTLSHSKSESREEQADSESSESLNFSEESP-ESPEDE 425

Query: 789 SRCSDEERPSTSRACVVNGPDEVAKTKPRHAMKRKRTADKSTSTSDPVI--EDDHVQVLV 846
           +  S E   S S +      +  ++     +    R+ + S ST       ED  ++ + 
Sbjct: 426 NSSSQEGLQSHSSSAESQSEESHSEEDDSDSQDSSRSKEDSNSTESKSSSEEDGQLKNIE 485

Query: 847 LKSKNLVGVTMTNCGITDLVLKDC 870
           ++S+ L      N  I D    DC
Sbjct: 486 IESRKLTVDAYHNKPIGDQDDNDC 509


>gi|121256621 dentin matrix acidic phosphoprotein 1 isoform 2
           precursor [Homo sapiens]
          Length = 497

 Score = 38.1 bits (87), Expect = 0.047
 Identities = 80/384 (20%), Positives = 142/384 (36%), Gaps = 42/384 (10%)

Query: 517 DDSDEENDFRQDLQPGEQQFAADALNEMEDIVQEDGEVVAESGNNTPAHSQAIIPVDVDE 576
           +DSD+     ++  P  Q  A D  +E  ++  ED       G ++   S++      +E
Sbjct: 122 EDSDDTIQASEESAPQGQDSAQDTTSESRELDNEDRVDSKPEGGDSTQESES------EE 175

Query: 577 EQAGPSGLQRVVKPTSITVHDSESDDEEDSLELQEVWIPKNGTRRYSEREEKTGESVQSR 636
              G           S     SE DDE    +  E    + G  R +    K+ ES ++ 
Sbjct: 176 HWVGGGS-----DGESSHGDGSELDDEGMQSDDPESIRSERGNSRMNSAGMKSKESGENS 230

Query: 637 ELSVSGKGKTPLRKRYNSHQMGQSKQFPLEESSCEKGCQVTSEQIKADM---KAARDI-- 691
           E + +          + S ++ +  +   E+   E     T E++K+D      +RD   
Sbjct: 231 EQANTQDSGGSQLLEHPSRKIFRKSRISEEDDRSELDDNNTMEEVKSDSTENSNSRDTGL 290

Query: 692 ------------PEKKKNKDVYPSCS----STTASTVGNSSSHNTASQSPDFVRTVNSGG 735
                        + K+N     S +    S+ +S   N SS   +S+S + V + + G 
Sbjct: 291 SQPRRDSKGDSQEDSKENLSQEESQNVDGPSSESSQEANLSSQENSSESQEEVVSESRGD 350

Query: 736 SSEPSPTEV------DVSRQCACSPGGSEDSEAMEE-GDAESSVCPRCCCHRPQESQRRT 788
           + +P+ + V      D S + +        SE+ EE  D+ESS         P ES    
Sbjct: 351 NPDPTTSYVEDQEDSDSSEEDSSHTLSHSKSESREEQADSESSESLNFSEESP-ESPEDE 409

Query: 789 SRCSDEERPSTSRACVVNGPDEVAKTKPRHAMKRKRTADKSTSTSDPVI--EDDHVQVLV 846
           +  S E   S S +      +  ++     +    R+ + S ST       ED  ++ + 
Sbjct: 410 NSSSQEGLQSHSSSAESQSEESHSEEDDSDSQDSSRSKEDSNSTESKSSSEEDGQLKNIE 469

Query: 847 LKSKNLVGVTMTNCGITDLVLKDC 870
           ++S+ L      N  I D    DC
Sbjct: 470 IESRKLTVDAYHNKPIGDQDDNDC 493


>gi|7656879 ALL1 fused gene from 5q31 [Homo sapiens]
          Length = 1163

 Score = 38.1 bits (87), Expect = 0.047
 Identities = 47/192 (24%), Positives = 70/192 (36%), Gaps = 22/192 (11%)

Query: 615 PKNGTRRYSEREEKTGESVQSRELSVSGKGKTPLRKRYNSHQMGQSKQFPLEESSCEKGC 674
           PK   +   E+  +  +   S ++S  GK K    K  + ++  +SK+ P  E     G 
Sbjct: 737 PKGEKKNVPEKHTREAQKQASEKVSNKGKRK---HKNEDDNRASESKK-PKTEDKNSAGH 792

Query: 675 QVTSEQIKADMKAARDIPEKKKNKDVYPSCSSTTAST---VGNSSSHNTASQSPDFVRTV 731
           + +S +  +   AA       K KD+ PS +    S      + S   T SQS     + 
Sbjct: 793 KPSSNRESSKQSAA-------KEKDLLPSPAGPVPSKDPKTEHGSRKRTISQSSSLKSSS 845

Query: 732 NS-----GGSSEPSPTEVDVSRQCACSPGGSEDSEAMEEGDAESSVCPRCCCHRPQESQR 786
           NS     G S   S T      +   S   S   E  E+  + SS CP           R
Sbjct: 846 NSNKETSGSSKNSSSTSKQKKTEGKTS---SSSKEVKEKAPSSSSNCPPSAPTLDSSKPR 902

Query: 787 RTSRCSDEERPS 798
           RT    D+   S
Sbjct: 903 RTKLVFDDRNYS 914


>gi|33356174 pinin, desmosome associated protein [Homo sapiens]
          Length = 717

 Score = 37.7 bits (86), Expect = 0.061
 Identities = 65/310 (20%), Positives = 123/310 (39%), Gaps = 56/310 (18%)

Query: 522 ENDFRQDLQPGEQQFAADALNEMEDIVQEDGEVV----------AESGNNTPAHSQAIIP 571
           E++ +QD QP E     + +  ++ ++  D EV+          +E+  +     +    
Sbjct: 374 ESEKQQDSQPEEVMDVLEMVENVKHVIA-DQEVMETNRVESVEPSENEASKELEPEMEFE 432

Query: 572 VDVDEEQAGPSGLQRVVKPTSITVHDSESDDEEDSLELQEVWIPKNGTRRYSEREEKTGE 631
           ++ D+E    S  +  V    +     E +++E   + + V  P+  ++   + + ++  
Sbjct: 433 IEPDKECKSLSPGKENVSALDMEKESEEKEEKESEPQPEPVAQPQPQSQPQLQLQSQSQP 492

Query: 632 SVQSR------ELSVSGKGKTPLRKRYNSHQMGQSKQFPLE-----ESSCEKGCQVTSEQ 680
            +QS+      +LS++    TP   +   H + + K FP+E     E   E    V  E 
Sbjct: 493 VLQSQPPSQPEDLSLAVLQPTPQVTQEQGHLLPERKDFPVESVKLTEVPVEPVLTVHPES 552

Query: 681 IKADMKA-------ARDIPEKKKNKDVYPSCSS---TTASTVGNSSSHNTASQSPDFVRT 730
            K+  K        AR+   K +++    S SS   T++S+  +SSS +++S+S      
Sbjct: 553 -KSKTKTRSRSRGRARNKTSKSRSRSSSSSSSSSSSTSSSSGSSSSSGSSSSRS------ 605

Query: 731 VNSGGSSEPSPTEVDVSRQCACSPGGSEDSEAMEEGDAESSVCPRCCCHRPQESQRRTSR 790
                SS  S T    SR  + S   S +S +   G             R     R+  R
Sbjct: 606 ----SSSSSSSTSGSSSRDSSSSTSSSSESRSRSRG-------------RGHNRDRKHRR 648

Query: 791 CSDEERPSTS 800
             D +R  TS
Sbjct: 649 SVDRKRRDTS 658


>gi|63054848 coiled-coil domain containing 34 isoform 1 [Homo
           sapiens]
          Length = 373

 Score = 37.4 bits (85), Expect = 0.080
 Identities = 41/202 (20%), Positives = 81/202 (40%), Gaps = 27/202 (13%)

Query: 510 DNNHHHPDDSDEENDFRQDLQPGEQQFAADALNEMEDIVQEDGEVVAESGNNTPAHSQAI 569
           D +    +D D+E D  +D    E + A+  L  ME  +Q       ES NN     Q  
Sbjct: 81  DGDGEDEEDVDDEEDVDEDAHDSEAKVAS--LRGME--LQGCASTQVESENNQEEQKQVR 136

Query: 570 IP-----------VDVDEEQAGPSGLQRVVKPTSITVHDSESDDEED----SLELQEVWI 614
           +P           +  ++E+     L+ + +         E ++ E     + E  + W+
Sbjct: 137 LPESRLTPWEVWFIGKEKEERDRLQLKALEELNQQLEKRKEMEEREKRKIIAEEKHKEWV 196

Query: 615 PKNGTRRYSEREEKTGESVQSRELSVSGKGKTPLRKRYNSHQMGQSKQFPLEESSCEKGC 674
            K   ++  ERE+K  + ++        K    L K Y   +  +  Q  L++ + E+ C
Sbjct: 197 QKKNEQKRKEREQKINKEMEE-------KAAKELEKEYLQEKAKEKYQEWLKKKNAEE-C 248

Query: 675 QVTSEQIKADMKAARDIPEKKK 696
           +   ++ + + +   +I EKK+
Sbjct: 249 ERKKKEKEKEKQQQAEIQEKKE 270


>gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens]
          Length = 2752

 Score = 37.4 bits (85), Expect = 0.080
 Identities = 70/321 (21%), Positives = 113/321 (35%), Gaps = 64/321 (19%)

Query: 517  DDSDEENDFRQDLQPGEQQFAADALNEMEDIVQEDGEVVAESGNNTPAHSQAIIPVDVDE 576
            D S E     Q  +P  +  ++  LN      Q +      SG+ +    + +    + +
Sbjct: 1481 DSSPEPKALPQTPRPRSRSPSSPELNNKCLTPQRE-----RSGSESSVDQKTVARTPLGQ 1535

Query: 577  EQAGPSGLQRVVKPTSITVHDSESDDEEDSLELQEVWIPKNGTRRYSEREEKTGESVQSR 636
                 S  +  VKP++     SESD   DS         K  TR    +  ++G S +  
Sbjct: 1536 RSRSGSSQELDVKPSASPQERSESDSSPDS---------KAKTRTPLRQRSRSGSSPE-- 1584

Query: 637  ELSVSGKGK-TPLRKRYNSHQMGQSKQFPLEESSCEKGCQVTSEQIKADMKAARDIPEKK 695
               V  K + +P R R  S    + K  P      + G   +S + KA   A R +P + 
Sbjct: 1585 ---VDSKSRLSPRRSRSGSSP--EVKDKPRAAPRAQSGSD-SSPEPKA--PAPRALPRRS 1636

Query: 696  KNKDVYPSCSSTTASTVGNSSSHNTASQSPDFVRTVNSGGSSEPSPTEVDVSRQCACSPG 755
            ++     S S     +   SSS  ++ + P   RT   G  S P P              
Sbjct: 1637 RS----GSSSKGRGPSPEGSSSTESSPEHPPKSRTARRGSRSSPEP-------------- 1678

Query: 756  GSEDSEAMEEGDAESSVCPRCCCHRPQESQRRTSRCSDEERPSTSRACVVNGPDEVAKTK 815
                         +S   PR    R      R +R S   R ++S       P+  ++T 
Sbjct: 1679 -----------KTKSRTPPRRRSSRSSPELTRKARLSRRSRSASS------SPETRSRTP 1721

Query: 816  PRH----AMKRKRTADKSTST 832
            PRH    ++     A+KS S+
Sbjct: 1722 PRHRRSPSVSSPEPAEKSRSS 1742



 Score = 37.0 bits (84), Expect = 0.10
 Identities = 39/186 (20%), Positives = 69/186 (37%), Gaps = 9/186 (4%)

Query: 624  EREEKTGESVQSRELSVSGKGKTPLRKRYNSHQMGQSKQFPLEESSCEKGCQVTSEQIKA 683
            ER   +  S  S   S S    +      +S    +    P++     K     +   K 
Sbjct: 2529 ERRSSSSSSSSSSSSSSSSSSSSSSSSSGSSSSDSEGSSLPVQPEVALKRVPSPTPAPKE 2588

Query: 684  DMKAARD---IPEKKKNKDVYPSCSSTTASTVGNSSSHNTASQSPDFVRTVNSGGSSEPS 740
             ++  R     P K+K +    S SS+++S+  +SSS +++S S     + +S  SS  S
Sbjct: 2589 AVREGRPPEPTPAKRKRRSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2648

Query: 741  PTEVDVSRQCACSPGG------SEDSEAMEEGDAESSVCPRCCCHRPQESQRRTSRCSDE 794
            P+      Q    P         E          +S    R   + P E +R + + S  
Sbjct: 2649 PSPAKPGPQALPKPASPKKPPPGERRSRSPRKPIDSLRDSRSLSYSPVERRRPSPQPSPR 2708

Query: 795  ERPSTS 800
            ++ S+S
Sbjct: 2709 DQQSSS 2714



 Score = 36.2 bits (82), Expect = 0.18
 Identities = 33/138 (23%), Positives = 60/138 (43%), Gaps = 11/138 (7%)

Query: 698  KDVYPSCSSTTASTVGNSSSHNTASQSPDFVRTVNSGGSSEPSPTEVDVSRQCACSPGGS 757
            K+   S SS+++S+  +SSS +++S S     + +S GSS P   EV + R  + +P   
Sbjct: 2528 KERRSSSSSSSSSSSSSSSSSSSSSSSSSGSSSSDSEGSSLPVQPEVALKRVPSPTPA-- 2585

Query: 758  EDSEAMEEGDAESSVCPRCCCHRPQESQRRTSRCSDEERPSTSRACVVNGPDEVAKTKPR 817
               EA+ EG              P + +RR+S  S     S+S +   +     + +   
Sbjct: 2586 -PKEAVREGRPPEPT--------PAKRKRRSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2636

Query: 818  HAMKRKRTADKSTSTSDP 835
             +     ++  S S + P
Sbjct: 2637 SSSSSSSSSSSSPSPAKP 2654



 Score = 32.3 bits (72), Expect = 2.6
 Identities = 49/236 (20%), Positives = 78/236 (33%), Gaps = 24/236 (10%)

Query: 615  PKNGTRRYSEREEKTGESVQSRELSVSG------------KGKTPLRKRYNSHQMGQSKQ 662
            PK    R   R  ++G S + R  S  G            K +T  R   +S +     +
Sbjct: 1624 PKAPAPRALPRRSRSGSSSKGRGPSPEGSSSTESSPEHPPKSRTARRGSRSSPEPKTKSR 1683

Query: 663  FPLEESSCEKGCQVTSE-QIKADMKAARDIPEKKKNKDVY----PSCSSTTASTVGNSSS 717
             P    S     ++T + ++    ++A   PE +          PS SS   +    SS 
Sbjct: 1684 TPPRRRSSRSSPELTRKARLSRRSRSASSSPETRSRTPPRHRRSPSVSSPEPAEKSRSSR 1743

Query: 718  HNTASQSPDFVRTVNSGGSSEPSPTEVDVSRQCACSPGGSEDSEAMEEGDAESSVCPRCC 777
               ++ SP    T   G S  P P  +  SR  +              G ++S+      
Sbjct: 1744 RRRSASSPRTKTTSRRGRSPSPKPRGLQRSRSRSRREKTRTTRRRDRSGSSQST------ 1797

Query: 778  CHRPQESQRRTSRCSDEERPSTSRACVVNGPDEVAKTKPRHAMKRKRTADKSTSTS 833
              R ++  R  SR +   R  +          E ++T  R    R RT   S   S
Sbjct: 1798 -SRRRQRSRSRSRVTRRRRGGSGYHSRSPARQESSRTSSRRRRGRSRTPPTSRKRS 1852


>gi|116256485 chromosome 6 open reading frame 10 [Homo sapiens]
          Length = 563

 Score = 36.6 bits (83), Expect = 0.14
 Identities = 52/255 (20%), Positives = 100/255 (39%), Gaps = 31/255 (12%)

Query: 469 KGCARVG-LSAGTGIGVSSALVSNQNSNNDDNNAQNNNANIHDNNHHHPDDSDEENDFRQ 527
           K C+++  L  G      ++   N+ +  +D    N+  ++   +   P+   +  D  +
Sbjct: 226 KSCSKIQILKCGGTARSQNSREENKEALKNDIIFTNSVESLKSAHIKEPEREGKGTDLEK 285

Query: 528 DLQPGEQQFAADA-----------LNEMEDIVQEDGEVVAESGNNTPAHSQAIIPVDVDE 576
           D    E +  +DA           ++EM  I Q  G  + +S ++ P   ++ +      
Sbjct: 286 DKIGMEVKVDSDAGIPKRQETQLKISEMS-IPQGQGAQIKKSVSDVPRGQESQVK---KS 341

Query: 577 EQAGPSGLQRVVKPTSITVHDSESDDEEDSLELQEVWIPKNGTRRYSEREEKTGESVQSR 636
           E   P G +  V  + + V   +    E  +E  E+ +P+        R+E   +  QS 
Sbjct: 342 ESGVPKGQEAQVTKSGLVVLKGQ----EAQVEKSEMGVPR--------RQESQVKKSQS- 388

Query: 637 ELSVSGKGKTPLRKRYNSHQMGQSKQFPLEESSCEKGCQVTSEQIKADMKAARDIPEKKK 696
              VS   +  ++KR +    GQ  Q    E    KG +   E+ +AD+   +++ EKK 
Sbjct: 389 --GVSKGQEAQVKKRESVVLKGQEAQVEKSELKVPKGQEGQVEKTEADVPKEQEVQEKKS 446

Query: 697 NKDVYPSCSSTTAST 711
              V     S   +T
Sbjct: 447 EAGVLKGPESQVKNT 461


>gi|126362967 Nck-associated protein 5 isoform 1 [Homo sapiens]
          Length = 1909

 Score = 36.2 bits (82), Expect = 0.18
 Identities = 35/142 (24%), Positives = 62/142 (43%), Gaps = 15/142 (10%)

Query: 667  ESSCEKGCQVTSE-------QIKADMKAARDIPEKKKNKDVYPSCSSTTASTVGNSSSHN 719
            + SC  G  ++++       +IKADM+  +D   K+ N+++        A +V  S    
Sbjct: 1651 QGSCLIGSSISTQGNHKKNMKIKADMEVPKDSLVKEANENLQEDEDDAVADSVFQSHIIE 1710

Query: 720  TASQSPDFVRTVNSGGSSEPSPTEVDVSR-QCACSPGGSEDSEAMEEGDAESSVCPRCCC 778
            +  Q    +RT++SG  + P P   + S  +  C P   ED+E +    +  S       
Sbjct: 1711 SNCQ----MRTLDSGIGTFPLPDSGNRSTGRYLCQPDSPEDAEPLLPLQSALSAVSSM-- 1764

Query: 779  HRPQESQRRTSRCSDEERPSTS 800
             R Q  +R     +D +RP+ S
Sbjct: 1765 -RAQTLEREVPSSTDGQRPADS 1785



 Score = 30.8 bits (68), Expect = 7.5
 Identities = 75/403 (18%), Positives = 142/403 (35%), Gaps = 57/403 (14%)

Query: 486  SALVSNQNSNNDDNNAQNNNANIHDNNHHHPDDSDEENDFRQDLQPGEQQFAADALNEME 545
            S L  N++ ++  +++ ++++    +N  H   S  E   +  L  G +      L +  
Sbjct: 1103 SFLGVNESPSSQVSSSSSSSSPAKSHNSPHGCQSAHEKGLKTRLPVGLK-----VLMKSP 1157

Query: 546  DIVQEDGEVVAESGN---NTPAHSQAIIPVDVDEEQAGPSGLQRVVKPTSITVHDSESDD 602
             ++++   V  +      N  + S   +     E+   P+ ++      ++T+ DS++  
Sbjct: 1158 QLLRKSSTVPGKHEKDSLNEASKSSVAVNKSKPEDSKNPASMEITAGERNVTLPDSQAQG 1217

Query: 603  E-EDSLELQE-VWIPKNGTRRYSEREEKTGESVQSRELSVS--------GKGKTPLRKRY 652
               D L L+  +  P   +   S+  +        R LS S        G      R   
Sbjct: 1218 SLADGLPLETALQEPLESSIPGSDGRDGVDNRSMRRSLSSSKPHLKPALGMNGAKARSHS 1277

Query: 653  NSHQMGQSKQFPLEESSCEKGCQVTSEQIKADMKAARDIPEKKKNKDVYPSCSSTTA-ST 711
             S   G     P  E S +   Q+ +   +      R     + + +  PS     +  +
Sbjct: 1278 FSTHSGDKPSTPPIEGSGKVRTQIITNTAERGNSLTRQNSSTESSPNKAPSAPMLESLPS 1337

Query: 712  VGNSSSHNTASQSPDFVRTVNSGGS-----SEPS--PTEVDVSRQCACSPGGSEDSEAME 764
            VG  S H ++ +      ++ S GS       PS  P  +    +    P G ED +A  
Sbjct: 1338 VGRPSGHPSSGKG-----SLGSSGSFSSQHGSPSKLPLRIPPKSEGLLIPPGKEDQQAFT 1392

Query: 765  EGDAESS-------------VCP--RCCCHRPQESQRRTSRCSDEERPSTSRACVVNGPD 809
            +G+  S+              CP     C    +S  RT   S  E  STS+        
Sbjct: 1393 QGECPSANVAVLGEPGSDRRSCPPTPTDCPEALQSPGRTQHPSTFETSSTSK-------- 1444

Query: 810  EVAKTKPRHAMKRKRTADKSTSTSDPVIEDDHVQVLVLKSKNL 852
               +T  RH      TA  + S+  P+      +V++   +N+
Sbjct: 1445 --LETSGRHP-DASATATDAVSSEAPLSPTIEEKVMLCIQENV 1484


>gi|21361272 myeloid/lymphoid or mixed-lineage leukemia (trithorax
           homolog, Drosophila); translocated to, 1 [Homo sapiens]
          Length = 559

 Score = 36.2 bits (82), Expect = 0.18
 Identities = 55/255 (21%), Positives = 107/255 (41%), Gaps = 35/255 (13%)

Query: 615 PKNGTRRYSEREEKTGESVQSRELSVSGKGKTPLRKRYNSHQMGQSKQFPLEESSCEKGC 674
           P+  ++R +  +     + + ++ S  G    P      S     S + P ++ S  +G 
Sbjct: 280 PRASSKRPATADSPKPSAKKQKKSSSKGSRSAPGTSPRTSSSSSFSDKKPAKDKSSTRGE 339

Query: 675 QVTSEQIKADMKAARDIPEKKKNKDVYPSCSSTTASTVGNSSSHNTASQSPDF------- 727
           +V +E    + K A ++ E+  ++D     S +  S+  NSSS + +S   DF       
Sbjct: 340 KVKAESEPREAKKALEV-EESNSEDEASFKSESAQSSPSNSSSSSDSSSDSDFEPSQNHS 398

Query: 728 ---VRTVNSGGSSEPSPTEVDVSRQCAC---SPGGSED---SEAMEEGDAESSVCPRCCC 778
              +R++     SE S  +   S + A    +PG       S++  +  A+SS+ P    
Sbjct: 399 QGPLRSMVEDLQSEESDEDDSSSGEEAAGKTNPGRDSRLSFSDSESDNSADSSL-PSREP 457

Query: 779 HRPQESQRRTSRCSDEERPSTSRACVVNGPDEVAKTKPRHAMKRKRTADKSTSTSDPVIE 838
             PQ+     S+ S    P +              +KP   +K K T DK  + +D ++E
Sbjct: 458 PPPQKPPPPNSKVSGRRSPESC-------------SKPEKILK-KGTYDK--AYTDELVE 501

Query: 839 DDHVQVLVLKSKNLV 853
             H +++ L+ +N++
Sbjct: 502 -LHRRLMALRERNVL 515


>gi|239755326 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 375

 Score = 36.2 bits (82), Expect = 0.18
 Identities = 40/134 (29%), Positives = 54/134 (40%), Gaps = 22/134 (16%)

Query: 703 SC-SSTTASTVGNSSSHNTAS----QSPDFVRTVNSGGSSEPSPTEVDVSRQCACSPGGS 757
           SC SS T+ST  N  S  T+S    QS     T  S  SSE S T       C+C   G+
Sbjct: 41  SCQSSGTSSTSCNWQSSRTSSTCSCQSSGTSSTSCSCQSSETSST-------CSCQSSGT 93

Query: 758 EDSEAMEEGDAESSVCPRCCCHRPQESQRRTSRCSDEERPSTSRACVVNGPDEVAKTKPR 817
             +    +    SS    CCC   + S    S C      STS +C      + ++T   
Sbjct: 94  SSTSCSWQFSRTSST---CCCQSSRTSSTSCS-CQSSRTSSTSCSC------QSSRTSST 143

Query: 818 HAMKRKRTADKSTS 831
            + +  RT+  S S
Sbjct: 144 CSCQTSRTSSTSCS 157



 Score = 32.7 bits (73), Expect = 2.0
 Identities = 24/111 (21%), Positives = 42/111 (37%), Gaps = 13/111 (11%)

Query: 703 SCSSTTASTVGNSSSHNTASQSPDFVRTVNSGGSSEPSPTEVDVSRQCACSPGGSEDSEA 762
           +CS  ++ T   S S  ++  S       +   S+  S      S  C+C   G+  +  
Sbjct: 235 TCSCQSSGTSSTSCSWQSSRTSSTCSCQSSGTSSTSCSCQSSGTSSTCSCQSSGTSSTSC 294

Query: 763 MEEGDAESSVC---------PRCCCHRPQESQRRTSRCSDEERPSTSRACV 804
             +    SS C           C C    +S R +S CS +   ++S +C+
Sbjct: 295 SCQSSRTSSTCSCQFSRTSSTSCSC----QSSRTSSTCSCQSSGTSSTSCI 341



 Score = 30.4 bits (67), Expect = 9.7
 Identities = 25/112 (22%), Positives = 45/112 (40%), Gaps = 17/112 (15%)

Query: 703 SCSSTTASTVGNSSSHNTASQSPDFVRTVNSGGSSEPSPT--EVDVSRQCACSPGGSEDS 760
           +CS  ++ T  +S+S++  S       +  S G+S  S +      S  C+C   G+  +
Sbjct: 189 TCSCQSSGT--SSTSYSCQSSGTSSTCSCQSSGTSSTSCSCQSSGTSSTCSCQSSGTSST 246

Query: 761 EAMEEGDAESSVC---------PRCCCHRPQESQRRTSRCSDEERPSTSRAC 803
               +    SS C           C C    +S   +S CS +   ++S +C
Sbjct: 247 SCSWQSSRTSSTCSCQSSGTSSTSCSC----QSSGTSSTCSCQSSGTSSTSC 294


>gi|122937227 U2-associated SR140 protein [Homo sapiens]
          Length = 1029

 Score = 36.2 bits (82), Expect = 0.18
 Identities = 56/255 (21%), Positives = 93/255 (36%), Gaps = 46/255 (18%)

Query: 597  DSESDDEED--SLELQEVWIPKNGTR---------RYSEREEKTGESVQSRELSVSG--- 642
            + ES+DEED  S + +E  +  N  +         +YSE  E+    ++  EL V     
Sbjct: 797  EEESEDEEDTQSSKSEEHHLYSNPIKEEMTESKFSKYSEMSEEKRAKLREIELKVMKFQD 856

Query: 643  ---KGKTPLRKRYNSHQMGQSKQFPLEESSCEKGCQVTSEQIKADMKAARDIPEKKKNKD 699
                GK P +   +  +  +  +  L +   EK  +   E+ K D +      + KK KD
Sbjct: 857  ELESGKRPKKPGQSFQEQVEHYRDKLLQREKEKELERERERDKKDKEKLESRSKDKKEKD 916

Query: 700  VYPSCSSTTASTVGNSSSHNTASQSPDFVRTVNSGGSSEPSPTEVDVSRQCACSPGGSED 759
                C+ T          H+T+                 PSP+     R+       SE 
Sbjct: 917  ---ECTPTRKE---RKRRHSTS-----------------PSPSRSSSGRRVKSPSPKSER 953

Query: 760  SEAMEEGDAESSVCPRCCCHRPQESQRRT------SRCSDEERPSTSRACVVNGPDEVAK 813
            SE  E    ESS         P++  ++       SR     R S SR+   +G    ++
Sbjct: 954  SERSERSHKESSRSRSSHKDSPRDVSKKAKRSPSGSRTPKRSRRSRSRSPKKSGKKSRSQ 1013

Query: 814  TKPRHAMKRKRTADK 828
            ++  H   +K   +K
Sbjct: 1014 SRSPHRSHKKSKKNK 1028


>gi|22035679 AT rich interactive domain 4B isoform 2 [Homo sapiens]
          Length = 1226

 Score = 36.2 bits (82), Expect = 0.18
 Identities = 77/396 (19%), Positives = 141/396 (35%), Gaps = 63/396 (15%)

Query: 484 VSSALVSNQNSNNDDNNAQNNNANIHDNNHHHPDDSDEENDFRQDLQPGEQQFAADALNE 543
           + + L ++++S  D        A   DNN       D   + R DL   E+Q ++  L E
Sbjct: 617 ILNGLQASESSAEDSEQEDERGAQDMDNNGKEESKIDHLTNNRNDLISKEEQNSSSLLEE 676

Query: 544 MEDIVQEDGEVVAESGNNTPAHSQAIIPVDVDEEQAGPSGLQRVVKPTSITVHDSESDDE 603
                                H+  +I   V +    P  L++      I V   ++D E
Sbjct: 677 ------------------NKVHADLVISKPVSK---SPERLRK-----DIEVLSEDTDYE 710

Query: 604 EDSLELQEVWIPKNGTRRYSEREEKTGES--VQSRELSVSGKGKTPLRKRYNSHQMGQSK 661
           ED +  +   + K+ T + S+ + K G+     + E   +G   +P +K     +  ++K
Sbjct: 711 EDEVTKKRKDVKKDTTDKSSKPQIKRGKRRYCNTEECLKTG---SPGKK----EEKAKNK 763

Query: 662 QFPLEESSCEKGCQVTSEQIKADM---KAARDIPEKKKNKDV------YPSCSSTTASTV 712
           +    E+S         E+ KA M   K    + EK+K+         +   +      +
Sbjct: 764 ESLCMENSSNSSSDEDEEETKAKMTPTKKYNGLEEKRKSLRTTGFYSGFSEVAEKRIKLL 823

Query: 713 GNSSSHNTASQSPDFVRTVNSGGSSEPSPTEVDVSRQCACSPGGSEDSEAMEEGDAESSV 772
            NS      S++ D     +S     P  T  ++          S    A EEG AE S+
Sbjct: 824 NNSDERLQNSRAKDRKDVWSSIQGQWPKKTLKELFSDSDTEAAASPPHPAPEEGVAEESL 883

Query: 773 ---------CPRCCCHRP-------QESQRRTSRCSDE--ERPSTSRACVVNGPDEVAKT 814
                     P     +P       +  + +T   +D   E PS+    V+N P    ++
Sbjct: 884 QTVAEEESCSPSVELEKPPPVNVDSKPIEEKTVEVNDRKAEFPSSGSNSVLNTPPTTPES 943

Query: 815 KPRHAMKRKRTADKSTSTSDPVIEDDHVQVLVLKSK 850
                +        S + S+P+  +   +V  +KS+
Sbjct: 944 PSSVTVTEGSRQQSSVTVSEPLAPNQE-EVRSIKSE 978


>gi|22035677 AT rich interactive domain 4B isoform 1 [Homo sapiens]
          Length = 1312

 Score = 36.2 bits (82), Expect = 0.18
 Identities = 77/396 (19%), Positives = 141/396 (35%), Gaps = 63/396 (15%)

Query: 484  VSSALVSNQNSNNDDNNAQNNNANIHDNNHHHPDDSDEENDFRQDLQPGEQQFAADALNE 543
            + + L ++++S  D        A   DNN       D   + R DL   E+Q ++  L E
Sbjct: 703  ILNGLQASESSAEDSEQEDERGAQDMDNNGKEESKIDHLTNNRNDLISKEEQNSSSLLEE 762

Query: 544  MEDIVQEDGEVVAESGNNTPAHSQAIIPVDVDEEQAGPSGLQRVVKPTSITVHDSESDDE 603
                                 H+  +I   V +    P  L++      I V   ++D E
Sbjct: 763  ------------------NKVHADLVISKPVSK---SPERLRK-----DIEVLSEDTDYE 796

Query: 604  EDSLELQEVWIPKNGTRRYSEREEKTGES--VQSRELSVSGKGKTPLRKRYNSHQMGQSK 661
            ED +  +   + K+ T + S+ + K G+     + E   +G   +P +K     +  ++K
Sbjct: 797  EDEVTKKRKDVKKDTTDKSSKPQIKRGKRRYCNTEECLKTG---SPGKK----EEKAKNK 849

Query: 662  QFPLEESSCEKGCQVTSEQIKADM---KAARDIPEKKKNKDV------YPSCSSTTASTV 712
            +    E+S         E+ KA M   K    + EK+K+         +   +      +
Sbjct: 850  ESLCMENSSNSSSDEDEEETKAKMTPTKKYNGLEEKRKSLRTTGFYSGFSEVAEKRIKLL 909

Query: 713  GNSSSHNTASQSPDFVRTVNSGGSSEPSPTEVDVSRQCACSPGGSEDSEAMEEGDAESSV 772
             NS      S++ D     +S     P  T  ++          S    A EEG AE S+
Sbjct: 910  NNSDERLQNSRAKDRKDVWSSIQGQWPKKTLKELFSDSDTEAAASPPHPAPEEGVAEESL 969

Query: 773  ---------CPRCCCHRP-------QESQRRTSRCSDE--ERPSTSRACVVNGPDEVAKT 814
                      P     +P       +  + +T   +D   E PS+    V+N P    ++
Sbjct: 970  QTVAEEESCSPSVELEKPPPVNVDSKPIEEKTVEVNDRKAEFPSSGSNSVLNTPPTTPES 1029

Query: 815  KPRHAMKRKRTADKSTSTSDPVIEDDHVQVLVLKSK 850
                 +        S + S+P+  +   +V  +KS+
Sbjct: 1030 PSSVTVTEGSRQQSSVTVSEPLAPNQE-EVRSIKSE 1064


>gi|51873034 F-box and leucine-rich repeat protein 9 [Homo sapiens]
          Length = 223

 Score = 35.8 bits (81), Expect = 0.23
 Identities = 24/73 (32%), Positives = 35/73 (47%), Gaps = 4/73 (5%)

Query: 387 ITDIGMKAVNEVFSCIKYLAIYNCPHLHNPYNWISDHSRWTRLVDINLVRCHAL---KLD 443
           +TD G+ AV      +++LA+ +C  L +   W    S W RL  +NL  C  L    LD
Sbjct: 113 LTDNGLVAVARGCPSLEHLALSHCSRLSDK-GWAQAASSWPRLQHLNLSSCSQLIEQTLD 171

Query: 444 SFGQFIELLPSLE 456
           + GQ    L  L+
Sbjct: 172 AIGQACRQLRVLD 184


>gi|16306591 F-box and leucine-rich repeat protein 9 [Homo sapiens]
          Length = 223

 Score = 35.8 bits (81), Expect = 0.23
 Identities = 24/73 (32%), Positives = 35/73 (47%), Gaps = 4/73 (5%)

Query: 387 ITDIGMKAVNEVFSCIKYLAIYNCPHLHNPYNWISDHSRWTRLVDINLVRCHAL---KLD 443
           +TD G+ AV      +++LA+ +C  L +   W    S W RL  +NL  C  L    LD
Sbjct: 113 LTDNGLVAVARGCPSLEHLALSHCSRLSDK-GWAQAASSWPRLQHLNLSSCSQLIEQTLD 171

Query: 444 SFGQFIELLPSLE 456
           + GQ    L  L+
Sbjct: 172 AIGQACRQLRVLD 184


>gi|116875765 tight junction protein 1 isoform b [Homo sapiens]
          Length = 1668

 Score = 35.4 bits (80), Expect = 0.30
 Identities = 72/285 (25%), Positives = 109/285 (38%), Gaps = 39/285 (13%)

Query: 585 QRVVKPTSITVHDSESDDEEDSLELQEVWIPKNG----TRRYSEREEKTGESVQSRELSV 640
           ++V  P S    +  SD+EEDS + +E+  P++G      R SE+      S  SRE S+
Sbjct: 110 KKVQIPVSRPDPEPVSDNEEDSYD-EEIHDPRSGRSGVVNRRSEKIWPRDRSA-SRERSL 167

Query: 641 SGKGKTPLRKRYNSHQMGQSKQFPLEES--SCEKGCQVTS----EQIKADMKAARD--IP 692
           S +     R+   S Q  +  +  L +S  + E G ++ S    ++I  D  AARD  I 
Sbjct: 168 SPRSD---RRSVASSQPAKPTKVTLVKSRKNEEYGLRLASHIFVKEISQDSLAARDGNIQ 224

Query: 693 EK----KKNKDVYPSCSSTTASTVGNSSSHN-----------TASQSPDFVRTVNSGGSS 737
           E     K N  V  + S T A T+   S              T    PD   +++S  +S
Sbjct: 225 EGDVVLKINGTVTENMSLTDAKTLIERSKGKLKMVVQRDERATLLNVPDLSDSIHSANAS 284

Query: 738 EPSPTEVDVSRQCACSPGGSEDS---EAMEEGDAESSVCPRCCCHRPQESQRRTSRCSDE 794
           E      ++    +   G S D     +      + S       H PQ+    + R  DE
Sbjct: 285 ERDDIS-EIQSLASDHSGRSHDRPPRRSRSRSPDQRSEPSDHSRHSPQQPSNGSLRSRDE 343

Query: 795 ER---PSTSRACVVNGPDEVAKTKPRHAMKRKRTADKSTSTSDPV 836
           ER   P      V +  D   KT     ++R      S     PV
Sbjct: 344 ERISKPGAVSTPVKHADDHTPKTVEEVTVERNEKQTPSLPEPKPV 388


>gi|116875767 tight junction protein 1 isoform a [Homo sapiens]
          Length = 1748

 Score = 35.4 bits (80), Expect = 0.30
 Identities = 72/285 (25%), Positives = 109/285 (38%), Gaps = 39/285 (13%)

Query: 585 QRVVKPTSITVHDSESDDEEDSLELQEVWIPKNG----TRRYSEREEKTGESVQSRELSV 640
           ++V  P S    +  SD+EEDS + +E+  P++G      R SE+      S  SRE S+
Sbjct: 110 KKVQIPVSRPDPEPVSDNEEDSYD-EEIHDPRSGRSGVVNRRSEKIWPRDRSA-SRERSL 167

Query: 641 SGKGKTPLRKRYNSHQMGQSKQFPLEES--SCEKGCQVTS----EQIKADMKAARD--IP 692
           S +     R+   S Q  +  +  L +S  + E G ++ S    ++I  D  AARD  I 
Sbjct: 168 SPRSD---RRSVASSQPAKPTKVTLVKSRKNEEYGLRLASHIFVKEISQDSLAARDGNIQ 224

Query: 693 EK----KKNKDVYPSCSSTTASTVGNSSSHN-----------TASQSPDFVRTVNSGGSS 737
           E     K N  V  + S T A T+   S              T    PD   +++S  +S
Sbjct: 225 EGDVVLKINGTVTENMSLTDAKTLIERSKGKLKMVVQRDERATLLNVPDLSDSIHSANAS 284

Query: 738 EPSPTEVDVSRQCACSPGGSEDS---EAMEEGDAESSVCPRCCCHRPQESQRRTSRCSDE 794
           E      ++    +   G S D     +      + S       H PQ+    + R  DE
Sbjct: 285 ERDDIS-EIQSLASDHSGRSHDRPPRRSRSRSPDQRSEPSDHSRHSPQQPSNGSLRSRDE 343

Query: 795 ER---PSTSRACVVNGPDEVAKTKPRHAMKRKRTADKSTSTSDPV 836
           ER   P      V +  D   KT     ++R      S     PV
Sbjct: 344 ERISKPGAVSTPVKHADDHTPKTVEEVTVERNEKQTPSLPEPKPV 388


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.318    0.134    0.404 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 44,707,358
Number of Sequences: 37866
Number of extensions: 2100666
Number of successful extensions: 7697
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 14
Number of HSP's successfully gapped in prelim test: 169
Number of HSP's that attempted gapping in prelim test: 7387
Number of HSP's gapped (non-prelim): 422
length of query: 1113
length of database: 18,247,518
effective HSP length: 113
effective length of query: 1000
effective length of database: 13,968,660
effective search space: 13968660000
effective search space used: 13968660000
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 67 (30.4 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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