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Search of human proteins with 45439357
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|45439357 elongin A2 [Homo sapiens]
(753 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|45439357 elongin A2 [Homo sapiens] 1540 0.0
gi|208022641 elongin A [Homo sapiens] 609 e-174
gi|156938279 transcription elongation factor B polypeptide 3C [H... 488 e-138
gi|154816198 transcription elongation factor B polypeptide 3C-li... 485 e-137
gi|239757016 PREDICTED: similar to RNA polymerase II transcripti... 101 3e-21
gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens] 49 2e-05
gi|158854042 hypothetical protein LOC222183 [Homo sapiens] 47 9e-05
gi|42542379 serine/arginine repetitive matrix 1 [Homo sapiens] 47 9e-05
gi|224548936 hypothetical protein LOC100170229 [Homo sapiens] 46 1e-04
gi|239749594 PREDICTED: hypothetical protein XP_002347096 [Homo ... 45 2e-04
gi|60097902 filaggrin [Homo sapiens] 45 3e-04
gi|145199237 transcription elongation factor B polypeptide 3 bin... 45 3e-04
gi|41281612 zinc finger protein 828 [Homo sapiens] 44 4e-04
gi|7656879 ALL1 fused gene from 5q31 [Homo sapiens] 44 7e-04
gi|209862789 microtubule associated monoxygenase, calponin and L... 43 0.001
gi|239740773 PREDICTED: similar to diffuse panbronchiolitis crit... 43 0.001
gi|169218320 PREDICTED: similar to BCL2-associated transcription... 42 0.002
gi|188536004 zinc finger protein 469 [Homo sapiens] 42 0.002
gi|117938254 BCL2-associated transcription factor 1 isoform 3 [H... 42 0.002
gi|117938251 BCL2-associated transcription factor 1 isoform 2 [H... 42 0.002
gi|7661958 BCL2-associated transcription factor 1 isoform 1 [Hom... 42 0.002
gi|239756568 PREDICTED: similar to BCL2-associated transcription... 42 0.002
gi|66392157 RGD motif, leucine rich repeats, tropomodulin domain... 42 0.002
gi|238624188 diffuse panbronchiolitis critical region 1 protein ... 42 0.003
gi|62362414 c-abl oncogene 1, receptor tyrosine kinase isoform a... 42 0.003
gi|62362412 c-abl oncogene 1, receptor tyrosine kinase isoform b... 42 0.003
gi|239754748 PREDICTED: hypothetical protein [Homo sapiens] 42 0.003
gi|154800457 centrosomal protein 68kDa [Homo sapiens] 41 0.004
gi|122937267 lemur tyrosine kinase 3 [Homo sapiens] 41 0.005
gi|4504713 insulinoma-associated 1 [Homo sapiens] 41 0.005
>gi|45439357 elongin A2 [Homo sapiens]
Length = 753
Score = 1540 bits (3988), Expect = 0.0
Identities = 753/753 (100%), Positives = 753/753 (100%)
Query: 1 MAAGSTTLHAVEKLQVRLATKTEPKKLEKYLQKLSALPMTADILAETGIRKTVKRLRKHQ 60
MAAGSTTLHAVEKLQVRLATKTEPKKLEKYLQKLSALPMTADILAETGIRKTVKRLRKHQ
Sbjct: 1 MAAGSTTLHAVEKLQVRLATKTEPKKLEKYLQKLSALPMTADILAETGIRKTVKRLRKHQ 60
Query: 61 HVGDFARDLAARWKKLVLVDRNTRPGPQDPEESASRQRFGEALQDQEKAWGFPENATAPR 120
HVGDFARDLAARWKKLVLVDRNTRPGPQDPEESASRQRFGEALQDQEKAWGFPENATAPR
Sbjct: 61 HVGDFARDLAARWKKLVLVDRNTRPGPQDPEESASRQRFGEALQDQEKAWGFPENATAPR 120
Query: 121 SPSHSPEHRRTARRTPPGQQRPHPRSHSREPRAERKCPRIAPADSGRYRASPTRTAPLRM 180
SPSHSPEHRRTARRTPPGQQRPHPRSHSREPRAERKCPRIAPADSGRYRASPTRTAPLRM
Sbjct: 121 SPSHSPEHRRTARRTPPGQQRPHPRSHSREPRAERKCPRIAPADSGRYRASPTRTAPLRM 180
Query: 181 PEGPEPAAPGKQPGRGHTHAAQGGPLLCPGCQGQPQGKAVVSHSKGHKSSRQEKRPLCAQ 240
PEGPEPAAPGKQPGRGHTHAAQGGPLLCPGCQGQPQGKAVVSHSKGHKSSRQEKRPLCAQ
Sbjct: 181 PEGPEPAAPGKQPGRGHTHAAQGGPLLCPGCQGQPQGKAVVSHSKGHKSSRQEKRPLCAQ 240
Query: 241 GDWHSPTLIREKSCGACLREETPRMPSWASARDRQPSDFKTDKEGGQAGSGQRVPALEEA 300
GDWHSPTLIREKSCGACLREETPRMPSWASARDRQPSDFKTDKEGGQAGSGQRVPALEEA
Sbjct: 241 GDWHSPTLIREKSCGACLREETPRMPSWASARDRQPSDFKTDKEGGQAGSGQRVPALEEA 300
Query: 301 PDSHQKRPQHSHSNKKRPSLDGRDPGNGTHGLSPEEKEQLSNDRETQEGKPPTAHLDRTS 360
PDSHQKRPQHSHSNKKRPSLDGRDPGNGTHGLSPEEKEQLSNDRETQEGKPPTAHLDRTS
Sbjct: 301 PDSHQKRPQHSHSNKKRPSLDGRDPGNGTHGLSPEEKEQLSNDRETQEGKPPTAHLDRTS 360
Query: 361 VSSLSEVEEVDMAEEFEQPTLSCEKYLTYDQLRKQKKKTGKSATTALGDKQRKANESKGT 420
VSSLSEVEEVDMAEEFEQPTLSCEKYLTYDQLRKQKKKTGKSATTALGDKQRKANESKGT
Sbjct: 361 VSSLSEVEEVDMAEEFEQPTLSCEKYLTYDQLRKQKKKTGKSATTALGDKQRKANESKGT 420
Query: 421 RESWDSAKKLPPVQESQSERLQAAGADSAGPKTVPSHVFSELWDLSEAWMQANYDPLSDS 480
RESWDSAKKLPPVQESQSERLQAAGADSAGPKTVPSHVFSELWDLSEAWMQANYDPLSDS
Sbjct: 421 RESWDSAKKLPPVQESQSERLQAAGADSAGPKTVPSHVFSELWDLSEAWMQANYDPLSDS 480
Query: 481 DSMTSQAKPEALSSPKFREEAAFPGRRVNAKMPVYSGSRPACQLQVPTLRQQCAQVLRNN 540
DSMTSQAKPEALSSPKFREEAAFPGRRVNAKMPVYSGSRPACQLQVPTLRQQCAQVLRNN
Sbjct: 481 DSMTSQAKPEALSSPKFREEAAFPGRRVNAKMPVYSGSRPACQLQVPTLRQQCAQVLRNN 540
Query: 541 PDALSDVGEVPYWVLEPVLEGWRPDQLYRRKKDNHALVRETDELRRNHCFQDFKEEKPQE 600
PDALSDVGEVPYWVLEPVLEGWRPDQLYRRKKDNHALVRETDELRRNHCFQDFKEEKPQE
Sbjct: 541 PDALSDVGEVPYWVLEPVLEGWRPDQLYRRKKDNHALVRETDELRRNHCFQDFKEEKPQE 600
Query: 601 NKTWREQYLRLPDAPEQRLRVMTTNIRSARGNNPNGREAKMICFKSVAKTPYDTSRRQEK 660
NKTWREQYLRLPDAPEQRLRVMTTNIRSARGNNPNGREAKMICFKSVAKTPYDTSRRQEK
Sbjct: 601 NKTWREQYLRLPDAPEQRLRVMTTNIRSARGNNPNGREAKMICFKSVAKTPYDTSRRQEK 660
Query: 661 SAGDADPENGEIKPASKPAGSSHTPSSQSSSGGGRDSSSSILRWLPEKRANPCLSSSNEH 720
SAGDADPENGEIKPASKPAGSSHTPSSQSSSGGGRDSSSSILRWLPEKRANPCLSSSNEH
Sbjct: 661 SAGDADPENGEIKPASKPAGSSHTPSSQSSSGGGRDSSSSILRWLPEKRANPCLSSSNEH 720
Query: 721 AAPAAKTRKQAAKKVAPLMAKAIRDYKRRFSRR 753
AAPAAKTRKQAAKKVAPLMAKAIRDYKRRFSRR
Sbjct: 721 AAPAAKTRKQAAKKVAPLMAKAIRDYKRRFSRR 753
>gi|208022641 elongin A [Homo sapiens]
Length = 798
Score = 609 bits (1570), Expect = e-174
Identities = 373/787 (47%), Positives = 487/787 (61%), Gaps = 52/787 (6%)
Query: 3 AGSTTLHAVEKLQVRLATKTEPKKLEKYLQKLSALPMTADILAETGIRKTVKRLRKHQHV 62
A + L VEKLQ RLA +PKKL KYL+KLS LP+T DILAETG+ KTV LRKH+HV
Sbjct: 28 AAESALQVVEKLQARLAANPDPKKLLKYLKKLSTLPITVDILAETGVGKTVNSLRKHEHV 87
Query: 63 GDFARDLAARWKKLVLVDRNTRPGPQDPEESASRQRFGEALQDQEKAWG-FPENATAPRS 121
G FARDL A+WKKLV V+RN P QD E+S SR+R +ALQ +E+ G + E A S
Sbjct: 88 GSFARDLVAQWKKLVPVERNAEPDEQDFEKSNSRKRPRDALQKEEEMEGDYQETWKATGS 147
Query: 122 PSHSPEHRRTARRTPPGQQRPHPRSHSREPRAERK-CPRIAP--------ADSGRYRASP 172
S+SP+HR+ R +RPH SH E R ERK C R++P +D G ++ P
Sbjct: 148 RSYSPDHRQKKHRKLSELERPHKVSHGHERRDERKRCHRMSPTYSSDPESSDYGHVQSPP 207
Query: 173 TRTAPLRM--------PEGPEPAAPGKQPGRGHTHAAQGGPLLCPGCQ-GQPQGKAVVSH 223
+ T+P +M E EP ++PG+GH++A Q G+P GK VVS
Sbjct: 208 SCTSPHQMYVDHYRSLEEDQEPIVSHQKPGKGHSNAFQDRLGASQERHLGEPHGKGVVSQ 267
Query: 224 SKGHKSSRQEKRPLCAQGDWHSPTLIREKSCGACLREETPRMPSWASARDRQPSDFKTDK 283
+K HKSS ++KRP+ A+ D + + REKS A +EE R PS +AR++ PS K
Sbjct: 268 NKEHKSSHKDKRPVDAKSDEKASVVSREKSHKALSKEENRRPPSGDNAREKPPSS-GVKK 326
Query: 284 EGGQAGSGQR---VPALEEAPDSHQKRPQH-----SHSNKKRPSLDGRDPGNGTHGLSPE 335
E + GS + +P E A D+H K+P+H + +K + LD D G G L P+
Sbjct: 327 EKDREGSSLKKKCLPPSEAASDNHLKKPKHRDPEKAKLDKSKQGLDSFDTGKGAGDLLPK 386
Query: 336 EKEQLSNDRETQEGKPPTAHLDRTSVSSLSEVEEVDMAEEFEQPTLSCEKYLTYDQLRKQ 395
KE+ SN+ +T EGK T +LDR S+ SL +VEE DM +EFEQPT+S E YL+YDQ RK+
Sbjct: 387 VKEKGSNNLKTPEGKVKT-NLDRKSLGSLPKVEETDMEDEFEQPTMSFESYLSYDQPRKK 445
Query: 396 KKKTGKSATTALGDKQRKANESKGTRESWDSAKKLPPVQESQSERLQAAGADSAGPKTVP 455
KKK K++ TALGDK K N+SK T ++ DS +KLP V +++SE+ AGAD A + VP
Sbjct: 446 KKKIVKTSATALGDKGLKKNDSKSTGKNLDSVQKLPKVNKTKSEK--PAGADLAKLRKVP 503
Query: 456 SHVFSELWDLSEAWMQANYDPLSDSDSMTS-QAKPEALSSPKFREEAAFPGRRVNAKMPV 514
V L DL +QANY PL + ++S Q K +A SSP+ EEA F GRR+N+KM V
Sbjct: 504 D-VLPVLPDLPLPAIQANYRPLPSLELISSFQPKRKAFSSPQEEEEAGFTGRRMNSKMQV 562
Query: 515 YSGSRPACQLQVPTLRQQCAQVLRNNPDALSDVGEVPYWVLEPVLEGWRPDQLYRRKKDN 574
YSGS+ A ++ TL QQC +VL+NN D++ +VG VPY VLEPVLE PDQLYR ++ N
Sbjct: 563 YSGSKCAYLPKMMTLHQQCIRVLKNNIDSIFEVGGVPYSVLEPVLERCTPDQLYRIEEYN 622
Query: 575 HALVRETDELRRNHCFQDFKEEKPQENKTWREQYLRLPDAPEQRLRVMTTNIRSARGNNP 634
H L+ ETD+L + HC +DFKEE+P+E ++WRE YLRL DA EQRLRV+T NI+ A N P
Sbjct: 623 HVLIEETDQLWKVHCHRDFKEERPEEYESWREMYLRLQDAREQRLRVLTKNIQFAHANKP 682
Query: 635 NGREAKMICFKSVAKTPYDTSRRQEK--SAGDADPENGEIKPASKPAGSSHTPSSQSSSG 692
GR+AKM SVAK P D RRQEK + G A PE +IKPA P GSSH +S S
Sbjct: 683 KGRQAKMAFVNSVAKPPRDVRRRQEKFGTGGAAVPEKIKIKPAPYPMGSSHASASSISFN 742
Query: 693 GGRDSSSSILRWLPEKRANPCLSSSNEHAAPAAKT------RKQAAKKVAPLMAKAIRDY 746
PE+ A S+S+ H AP + RK KK+AP+MAK I+ +
Sbjct: 743 PS-----------PEEPAYDGPSTSSAHLAPVVSSTVSYDPRKPTVKKIAPMMAKTIKAF 791
Query: 747 KRRFSRR 753
K RFSRR
Sbjct: 792 KNRFSRR 798
>gi|156938279 transcription elongation factor B polypeptide 3C [Homo
sapiens]
Length = 546
Score = 488 bits (1256), Expect = e-138
Identities = 277/460 (60%), Positives = 305/460 (66%), Gaps = 27/460 (5%)
Query: 295 PALEEAPDSHQKRPQHSHSNKKRPSLDGRDPGNGTHGLSPEEKEQLSNDRETQEGKPPTA 354
P AP S P+H + ++ P R H SP + + R
Sbjct: 113 PENATAPRSPSHSPEHRRTARRTPPGQQRP-----HPRSPSREPRAERKRPRMAPADSGP 167
Query: 355 HLDR-TSVSSLSEVEEVDMAEEFEQPTLSCEKYLTYDQLRKQKKKTGKSATTALGDKQRK 413
H D T + L E + A EQP L Q + G+ A+G +
Sbjct: 168 HRDPPTRTAPLPMPEGPEPAVPGEQPGRGHAHAAQGGPLLGQGCQ-GQPQGEAVGSHSKG 226
Query: 414 ANESKGTRESWDSAKKLPPVQESQSERLQAAGADSAGPKTVPSHVFSELWDLSEAWMQAN 473
S+G SA+K PPVQESQSERLQAAGADSAGPKTVPSHVFSELWD SEAWMQAN
Sbjct: 227 HKSSRGA-----SAQKSPPVQESQSERLQAAGADSAGPKTVPSHVFSELWDPSEAWMQAN 281
Query: 474 YDPLSDSDSMTSQAKPEALSSPKFREEAAFPGRRVNAKMPVYSGSRPACQLQVPTLRQQC 533
YD LS ++MTSQA PEALS+P +EEAAFPGRRVNAKMPVYSGSRPACQLQVPTLRQQC
Sbjct: 282 YDLLSAFEAMTSQANPEALSAPALQEEAAFPGRRVNAKMPVYSGSRPACQLQVPTLRQQC 341
Query: 534 AQVLRNNPDALSDVGEVPYWVLEPVLEGWRPDQLYRRKKDNHALVRETDELRRNHCFQDF 593
+V RNNPDAL DV VPY VLEPVLEGW PDQLYR +KDN AL RETDEL R HC QDF
Sbjct: 342 LRVPRNNPDALGDVEGVPYSVLEPVLEGWTPDQLYRTEKDNAALARETDELWRIHCLQDF 401
Query: 594 KEEKPQENKTWREQYLRLPDAPEQRLRVMTTNIRSARGNNPNGREAKMICFKSVAKTPYD 653
KEEKPQE+++WRE YLRL DA EQRLRV+TT IRSAR N P+GR+ KMICF SVAKTPYD
Sbjct: 402 KEEKPQEHESWRELYLRLRDAREQRLRVVTTKIRSARENKPSGRQTKMICFNSVAKTPYD 461
Query: 654 TSRRQEKSAGDADPENGEIKPASKPAGSSHTPSSQSSSGGGRDSSSSILRWLPEKRANPC 713
SRRQEKSAG ADP NGE++PA KPAGSS PS GG S
Sbjct: 462 ASRRQEKSAGAADPGNGEMEPAPKPAGSSQAPSGLGDGDGGSVSGG-------------- 507
Query: 714 LSSSNEHAAPAAKTRKQAAKKVAPLMAKAIRDYKRRFSRR 753
SSN HAAPA KTRKQAAKKVAPLMAKAIRDYK RFSRR
Sbjct: 508 -GSSNRHAAPADKTRKQAAKKVAPLMAKAIRDYKGRFSRR 546
Score = 426 bits (1094), Expect = e-119
Identities = 210/231 (90%), Positives = 216/231 (93%)
Query: 1 MAAGSTTLHAVEKLQVRLATKTEPKKLEKYLQKLSALPMTADILAETGIRKTVKRLRKHQ 60
MAAGSTTL AV KLQVRLATKTEPKKLEKYLQKLSALPMTADILAETGIRKTVKRLRKHQ
Sbjct: 1 MAAGSTTLRAVGKLQVRLATKTEPKKLEKYLQKLSALPMTADILAETGIRKTVKRLRKHQ 60
Query: 61 HVGDFARDLAARWKKLVLVDRNTRPGPQDPEESASRQRFGEALQDQEKAWGFPENATAPR 120
HVGDFARDLAARWKKLVLVDRNT P PQDPEESASRQRFGEALQ++EKAWGFPENATAPR
Sbjct: 61 HVGDFARDLAARWKKLVLVDRNTGPDPQDPEESASRQRFGEALQEREKAWGFPENATAPR 120
Query: 121 SPSHSPEHRRTARRTPPGQQRPHPRSHSREPRAERKCPRIAPADSGRYRASPTRTAPLRM 180
SPSHSPEHRRTARRTPPGQQRPHPRS SREPRAERK PR+APADSG +R PTRTAPL M
Sbjct: 121 SPSHSPEHRRTARRTPPGQQRPHPRSPSREPRAERKRPRMAPADSGPHRDPPTRTAPLPM 180
Query: 181 PEGPEPAAPGKQPGRGHTHAAQGGPLLCPGCQGQPQGKAVVSHSKGHKSSR 231
PEGPEPA PG+QPGRGH HAAQGGPLL GCQGQPQG+AV SHSKGHKSSR
Sbjct: 181 PEGPEPAVPGEQPGRGHAHAAQGGPLLGQGCQGQPQGEAVGSHSKGHKSSR 231
>gi|154816198 transcription elongation factor B polypeptide 3C-like
[Homo sapiens]
Length = 546
Score = 485 bits (1249), Expect = e-137
Identities = 276/460 (60%), Positives = 304/460 (66%), Gaps = 27/460 (5%)
Query: 295 PALEEAPDSHQKRPQHSHSNKKRPSLDGRDPGNGTHGLSPEEKEQLSNDRETQEGKPPTA 354
P AP S P+H + ++ P R H SP + + R
Sbjct: 113 PENATAPRSPSHSPEHRRTARRTPPGQQRP-----HPRSPSREPRAERKRPRMAPADSGP 167
Query: 355 HLDR-TSVSSLSEVEEVDMAEEFEQPTLSCEKYLTYDQLRKQKKKTGKSATTALGDKQRK 413
H D T + L E + A EQP L Q + G+ A+G +
Sbjct: 168 HRDPPTRTAPLPMPEGPEPAVPGEQPGRGHAHAAQGGPLLGQGCQ-GQPQGEAVGSHSKG 226
Query: 414 ANESKGTRESWDSAKKLPPVQESQSERLQAAGADSAGPKTVPSHVFSELWDLSEAWMQAN 473
S+G SA+K PPVQESQSERLQAAGADSAGPKTVPSHVFSELWD SEAWMQAN
Sbjct: 227 HKSSRGA-----SAQKSPPVQESQSERLQAAGADSAGPKTVPSHVFSELWDPSEAWMQAN 281
Query: 474 YDPLSDSDSMTSQAKPEALSSPKFREEAAFPGRRVNAKMPVYSGSRPACQLQVPTLRQQC 533
YD LS ++MTSQA PEALS+P +EEAAFPGRRVNAKMPVYSGSRPACQLQVPTLRQQC
Sbjct: 282 YDLLSAFEAMTSQANPEALSAPTLQEEAAFPGRRVNAKMPVYSGSRPACQLQVPTLRQQC 341
Query: 534 AQVLRNNPDALSDVGEVPYWVLEPVLEGWRPDQLYRRKKDNHALVRETDELRRNHCFQDF 593
+V RNNPDAL DV VPY VLEPVLEGW PDQ YR +KDN AL RETDEL R HC QDF
Sbjct: 342 LRVPRNNPDALGDVEGVPYSVLEPVLEGWTPDQPYRTEKDNAALARETDELWRIHCLQDF 401
Query: 594 KEEKPQENKTWREQYLRLPDAPEQRLRVMTTNIRSARGNNPNGREAKMICFKSVAKTPYD 653
KEEKPQE+++WRE YLRL DA EQRLRV+TT IRSAR N P+GR+ KMICF SVAKTPYD
Sbjct: 402 KEEKPQEHESWRELYLRLRDAREQRLRVVTTKIRSARENKPSGRQTKMICFNSVAKTPYD 461
Query: 654 TSRRQEKSAGDADPENGEIKPASKPAGSSHTPSSQSSSGGGRDSSSSILRWLPEKRANPC 713
SRRQEKSAG ADP NGE++PA KPAGSS PS GG S
Sbjct: 462 ASRRQEKSAGAADPGNGEMEPAPKPAGSSQAPSGLGDGDGGSVSGG-------------- 507
Query: 714 LSSSNEHAAPAAKTRKQAAKKVAPLMAKAIRDYKRRFSRR 753
SSN HAAPA KTRKQAAKKVAPLMAKAIRDYK RFSRR
Sbjct: 508 -GSSNRHAAPADKTRKQAAKKVAPLMAKAIRDYKGRFSRR 546
Score = 426 bits (1094), Expect = e-119
Identities = 210/231 (90%), Positives = 216/231 (93%)
Query: 1 MAAGSTTLHAVEKLQVRLATKTEPKKLEKYLQKLSALPMTADILAETGIRKTVKRLRKHQ 60
MAAGSTTL AV KLQVRLATKTEPKKLEKYLQKLSALPMTADILAETGIRKTVKRLRKHQ
Sbjct: 1 MAAGSTTLRAVGKLQVRLATKTEPKKLEKYLQKLSALPMTADILAETGIRKTVKRLRKHQ 60
Query: 61 HVGDFARDLAARWKKLVLVDRNTRPGPQDPEESASRQRFGEALQDQEKAWGFPENATAPR 120
HVGDFARDLAARWKKLVLVDRNT P PQDPEESASRQRFGEALQ++EKAWGFPENATAPR
Sbjct: 61 HVGDFARDLAARWKKLVLVDRNTGPDPQDPEESASRQRFGEALQEREKAWGFPENATAPR 120
Query: 121 SPSHSPEHRRTARRTPPGQQRPHPRSHSREPRAERKCPRIAPADSGRYRASPTRTAPLRM 180
SPSHSPEHRRTARRTPPGQQRPHPRS SREPRAERK PR+APADSG +R PTRTAPL M
Sbjct: 121 SPSHSPEHRRTARRTPPGQQRPHPRSPSREPRAERKRPRMAPADSGPHRDPPTRTAPLPM 180
Query: 181 PEGPEPAAPGKQPGRGHTHAAQGGPLLCPGCQGQPQGKAVVSHSKGHKSSR 231
PEGPEPA PG+QPGRGH HAAQGGPLL GCQGQPQG+AV SHSKGHKSSR
Sbjct: 181 PEGPEPAVPGEQPGRGHAHAAQGGPLLGQGCQGQPQGEAVGSHSKGHKSSR 231
>gi|239757016 PREDICTED: similar to RNA polymerase II transcription
factor SIII subunit A3, partial [Homo sapiens]
Length = 78
Score = 101 bits (251), Expect = 3e-21
Identities = 57/93 (61%), Positives = 59/93 (63%), Gaps = 15/93 (16%)
Query: 661 SAGDADPENGEIKPASKPAGSSHTPSSQSSSGGGRDSSSSILRWLPEKRANPCLSSSNEH 720
SAG ADP NGE++PA KPAGSS PS GG S SSN H
Sbjct: 1 SAGAADPGNGEMEPAPKPAGSSQAPSGLGDGDGGSGSGGG---------------SSNRH 45
Query: 721 AAPAAKTRKQAAKKVAPLMAKAIRDYKRRFSRR 753
AAPA KTRKQAAKKVAPLMAKAIRDYK RFSRR
Sbjct: 46 AAPADKTRKQAAKKVAPLMAKAIRDYKGRFSRR 78
>gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens]
Length = 2752
Score = 48.9 bits (115), Expect = 2e-05
Identities = 88/370 (23%), Positives = 124/370 (33%), Gaps = 52/370 (14%)
Query: 93 SASRQRFGEALQDQEKAWGFPENATAPRSPSHSPEHRRTARRTPPGQQRPHPRSHSREPR 152
S S QR+G + Q + + +P+ P S R T RR R RSHSR P
Sbjct: 516 SRSAQRWGRSRSPQRRG-----RSRSPQRPGWS-RSRNTQRRGRSRSAR-RGRSHSRSPA 568
Query: 153 AERKCPRIAPADSGRYRA-------SPTRTAPLRMPEGPEPAAPGKQPGRGHTHAAQGGP 205
+ PA GR R+ S +RT R PA G+ R P
Sbjct: 569 TRGRSRSRTPARRGRSRSRTPARRRSRSRTPTRRRSRSRTPARRGRSRSR--------TP 620
Query: 206 LLCPGCQGQPQGKAVVSHSKGHKSSRQEKRPLCAQGDWHSPTLIREKSCGACLREETPRM 265
P + S S +S R R +G S T R R TP
Sbjct: 621 ARRRSRTRSPVRRRSRSRSPARRSGRSRSRTPARRGRSRSRTPARRGRS----RSRTPAR 676
Query: 266 PSWASARDRQPSDFKTDKEGGQAGSGQRVPALEEAPDSHQKRPQ---HSHSNKKRPSLDG 322
S S R R P+ + R +L SH + PQ S S+ +R +
Sbjct: 677 RSGRS-RSRTPARRGRSRSRTPRRGRSRSRSLVRRGRSHSRTPQRRGRSGSSSERKNKSR 735
Query: 323 RDPGNGTHGLSPEEKEQLSNDRETQEGKPPTAHLDRTSVSSLSEVEEVDMAEEFEQPTLS 382
SPE K+ + R ++ P R+ S LS
Sbjct: 736 TSQRRSRSNSSPEMKKSRISSRRSRSLSSP-----RSKAKS----------------RLS 774
Query: 383 CEKYLTYDQLRKQKKKTGKSATTALGDKQRKANESKGTRESWDSAKKLPPVQESQSERLQ 442
+ L+ ++K + G Q KA R S S+ PP Q+S++ Q
Sbjct: 775 LRRSLSGSSPCPKQKSQTPPRRSRSGSSQPKAKSRTPPRRSRSSSSP-PPKQKSKTPSRQ 833
Query: 443 AAGADSAGPK 452
+ + S PK
Sbjct: 834 SHSSSSPHPK 843
Score = 41.2 bits (95), Expect = 0.004
Identities = 39/161 (24%), Positives = 61/161 (37%), Gaps = 13/161 (8%)
Query: 117 TAPRSPSHSPEHRRTARRTPPGQQRPHPRSHSREPRAERKCPRIAPADSGRYRASPTRTA 176
T RSP SPE + + P P SR + + P+ APA S + T+
Sbjct: 400 TRDRSPPKSPEKLPQSSSSESSPPSPQPTKVSRHASSSPESPKPAPAPGSHREISSSPTS 459
Query: 177 PLRMPEGPEPAAPGKQPGRGHTHAAQGGPLLCPGCQGQPQGKAVVSHSKGHKSSR--QEK 234
R + HT + + G P + + ++ +GH SR Q +
Sbjct: 460 KNR-----SHGRAKRDKSHSHTPSRRMGRSRSPATAKRGRSRSRTPTKRGHSRSRSPQWR 514
Query: 235 RPLCAQGDWHSPTLIREKSCGACLREETPRMPSWASARDRQ 275
R AQ W R +S R +P+ P W+ +R+ Q
Sbjct: 515 RSRSAQ-RWG-----RSRSPQRRGRSRSPQRPGWSRSRNTQ 549
Score = 39.3 bits (90), Expect = 0.014
Identities = 56/261 (21%), Positives = 90/261 (34%), Gaps = 18/261 (6%)
Query: 115 NATAPRSPSHSPEHRRTARRTPPGQQRPHPRSHSREPRAERKCPRIAPADSGRYRASPTR 174
N T+PR P + E R + R +PP R R+ P R AP+ S R +P++
Sbjct: 2379 NLTSPRVPLSAYE-RVSGRTSPPLLDRARSRTPPSAPSQSRMTSERAPSPSSRMGQAPSQ 2437
Query: 175 TAPLRMPEGPEPAAPGKQPGRGHTHAAQGGPLLCPGCQGQPQGKAVVSHSKG--HKSSRQ 232
+ + P P + AQ P+ G Q G + S H
Sbjct: 2438 SLLPPAQDQPRSPVPSAFSDQSRCLIAQTTPV--AGSQSLSSGAVATTTSSAGDHNGMLS 2495
Query: 233 EKRPLCAQGDWHSP---TLIREKSCGACL-----REETPRMPSWASARDRQPSDFKTDKE 284
P D P T ++ S A L R + S +S+ S +
Sbjct: 2496 VPAPGVPHSDVGEPPASTGAQQPSALAALQPAKERRSSSSSSSSSSSSSSSSSSSSSSSS 2555
Query: 285 GGQAGSGQRVPALEEAPDSHQKRPQHSHSNKKRPSLDGRDPGNGTHGLSPEEKEQLSNDR 344
G + S +L P+ KR K +GR P +P ++++ S+
Sbjct: 2556 SGSSSSDSEGSSLPVQPEVALKRVPSPTPAPKEAVREGRPPEP-----TPAKRKRRSSSS 2610
Query: 345 ETQEGKPPTAHLDRTSVSSLS 365
+ ++ +S SS S
Sbjct: 2611 SSSSSSSSSSSSSSSSSSSSS 2631
Score = 38.1 bits (87), Expect = 0.030
Identities = 62/279 (22%), Positives = 102/279 (36%), Gaps = 53/279 (18%)
Query: 80 DRNTRPGPQDPEESASRQRFGEALQDQEKAWGFPENATAPRSPSHSPEHRRTARRTPPGQ 139
D + P P R R G + + + + PE +++ S P RTARR +
Sbjct: 1619 DSSPEPKAPAPRALPRRSRSGSSSKGRGPS---PEGSSSTESSPEHPPKSRTARR--GSR 1673
Query: 140 QRPHPRSHSREPRAERKCPRIAPADSGRYRASPTRTAPLRMPEGPEPAAPGKQPGRGHTH 199
P P++ SR P R+ R +P + + R S + PE + P R
Sbjct: 1674 SSPEPKTKSRTP-PRRRSSRSSPELTRKARLSRRSRSASSSPE-----TRSRTPPRHRRS 1727
Query: 200 AAQGGPLLCPGCQGQPQGKAVVSHSKGHKSSRQEKRPLCAQGDWHSPTLIREKSCGACLR 259
+ P +P K+ +SSR+ + S + R K+ R
Sbjct: 1728 PSVSSP--------EPAEKS--------RSSRRRR----------SASSPRTKTTSRRGR 1761
Query: 260 EETPRMPSWASARDRQPSD-FKTDKEGGQAGSGQRVPALEEAPDSHQKRPQHSHSNKKRP 318
+P+ +R R + +T + ++GS Q S +R Q S S +
Sbjct: 1762 SPSPKPRGLQRSRSRSRREKTRTTRRRDRSGSSQ----------STSRRRQRSRSRSR-- 1809
Query: 319 SLDGRDPGNGTHGLSPEEKEQLSNDRETQEGK---PPTA 354
R G+G H SP +E + G+ PPT+
Sbjct: 1810 VTRRRRGGSGYHSRSPARQESSRTSSRRRRGRSRTPPTS 1848
Score = 37.0 bits (84), Expect = 0.068
Identities = 61/267 (22%), Positives = 87/267 (32%), Gaps = 34/267 (12%)
Query: 81 RNTRPGPQDPEE----SASRQRFGEALQDQEKAWGFPENATAPRSPSHSPEHRRTARRTP 136
R+T P P+ SA + + + ++ + TA S SP R
Sbjct: 249 RSTTPAPKSRRAHRSTSADSASSSDTSRSRSRSAAAKTHTTALAGRSPSPASGRRGEGDA 308
Query: 137 PGQQRPHPRSHSR--EPRAERKCPRIAPADSGRYRASPTRTAPLRMPE----GPEPAAPG 190
P + P S R P K P D + + + T P PE GPEP AP
Sbjct: 309 PFSE-PGTTSTQRPSSPETATKQPSSPYEDKDKDKKEKSATRPSPSPERSSTGPEPPAP- 366
Query: 191 KQPGRGHTHAAQGGPLLCPGCQGQPQGKAVVSHSKGHKSSRQEKRPLCAQGDWHSPTLIR 250
PLL G PQ A S+ + E P + SP +
Sbjct: 367 -------------TPLLAERHGGSPQPLATTPLSQEPVNPPSEASPTRDRSPPKSPEKLP 413
Query: 251 EKSCGACLREETPRMPSWASARDRQPSDFKTDKEGGQAGSGQRV---PALEEAPDSHQKR 307
+ S E +P P S ++ K GS + + P + KR
Sbjct: 414 QSSSS----ESSPPSPQPTKVSRHASSSPESPKPAPAPGSHREISSSPTSKNRSHGRAKR 469
Query: 308 PQ-HSHSNKKRPSLDGRDPGNGTHGLS 333
+ HSH+ +R R P G S
Sbjct: 470 DKSHSHTPSRRMG-RSRSPATAKRGRS 495
Score = 35.0 bits (79), Expect = 0.26
Identities = 27/92 (29%), Positives = 38/92 (41%), Gaps = 9/92 (9%)
Query: 95 SRQRFGEALQDQEKAWGFPENATAPRSPSHSPEHRRTARRTPPGQQR---------PHPR 145
SR R + + ++ P RS + RR+ RTPP +R P R
Sbjct: 1982 SRSRTSPVTRRRSRSRTSPVTRRRSRSRTSPVTRRRSRSRTPPAIRRRSRSRTPLLPRKR 2041
Query: 146 SHSREPRAERKCPRIAPADSGRYRASPTRTAP 177
S SR P A R+ R + R + S TR+ P
Sbjct: 2042 SRSRSPLAIRRRSRSRTPRTARGKRSLTRSPP 2073
Score = 33.5 bits (75), Expect = 0.75
Identities = 67/298 (22%), Positives = 95/298 (31%), Gaps = 74/298 (24%)
Query: 120 RSPSHSPEHRRTARRTPPGQQ-------------------------RPHPRSHSREPRAE 154
RS S S ++T RTP GQ+ P ++ +R P +
Sbjct: 1516 RSGSESSVDQKTVARTPLGQRSRSGSSQELDVKPSASPQERSESDSSPDSKAKTRTPLRQ 1575
Query: 155 RKCPRIAPADSGRYRASPTRTAPLRMPE-----------------GPEPAAPGKQ--PGR 195
R +P + R SP R+ PE PEP AP + P R
Sbjct: 1576 RSRSGSSPEVDSKSRLSPRRSRSGSSPEVKDKPRAAPRAQSGSDSSPEPKAPAPRALPRR 1635
Query: 196 GHTHAAQGGPLLCPGCQGQPQGKAVVSH-------SKGHKSSRQEK----RPLCAQGDWH 244
+ ++ G P +G ++ H +G +SS + K P +
Sbjct: 1636 SRSGSSSKG--RGPSPEGSSSTESSPEHPPKSRTARRGSRSSPEPKTKSRTPPRRRSSRS 1693
Query: 245 SPTLIREKSCGACLREETPRMPSWASARDRQPSDFKTDKEGGQAGSGQRVPALEEAPDSH 304
SP L R+ A L + S R R P + P E S
Sbjct: 1694 SPELTRK----ARLSRRSRSASSSPETRSRTPPRHRRSPSVSS-------PEPAEKSRSS 1742
Query: 305 QKRPQHSHSNKKRPSLDGRDPGNGTHGLSPEEKEQLSNDRETQEGKPPTAHLDRTSVS 362
++R S K S GR P GL Q S R +E T DR+ S
Sbjct: 1743 RRRRSASSPRTKTTSRRGRSPSPKPRGL------QRSRSRSRREKTRTTRRRDRSGSS 1794
Score = 31.2 bits (69), Expect = 3.7
Identities = 82/452 (18%), Positives = 145/452 (32%), Gaps = 36/452 (7%)
Query: 87 PQDPEESASRQRFGEALQDQEKAWGFPENATAPRSPSHSPEHRRTARRTPPGQQRPHPRS 146
P +P AS R + EK + ++P SP + R + + P P S
Sbjct: 390 PVNPPSEASPTRDRSPPKSPEKLPQSSSSESSPPSPQPTKVSRHASSSPESPKPAPAPGS 449
Query: 147 H---SREPRAERKCPRIAPADSGRYRASPTRTAPLRMPEGPEPAAPGKQPGRGHTHAAQG 203
H S P ++ + A D S + T RM PA + R T +G
Sbjct: 450 HREISSSPTSKNRSHGRAKRDK-----SHSHTPSRRMGRSRSPATAKRGRSRSRTPTKRG 504
Query: 204 ------------------GPLLCPGCQGQPQGKAVVSHSKGHKSSRQEKRPLCAQGDWHS 245
G P +G+ + S+ + R+ + +G HS
Sbjct: 505 HSRSRSPQWRRSRSAQRWGRSRSPQRRGRSRSPQRPGWSRSRNTQRRGRSRSARRGRSHS 564
Query: 246 PTLIREKSCGACLREETP----RMPSWASARDRQPSDFKTDKEGGQAGSGQRVPALEEAP 301
R + R TP R S AR R S T + +R + P
Sbjct: 565 ----RSPATRGRSRSRTPARRGRSRSRTPARRRSRSRTPTRRRSRSRTPARRGRSRSRTP 620
Query: 302 DSHQKRPQHSHSNKKRPSLDGRDPGNGTHGLSPEEKEQLSNDRETQEGKPPTAHLDRTSV 361
+ R + + R R G + +P + + + + G+ + R S
Sbjct: 621 ARRRSRTRSPVRRRSRSRSPARRSGR-SRSRTPARRGRSRSRTPARRGRSRSRTPARRSG 679
Query: 362 SSLSEVEEVDMAEEFEQPTLSCEKYLTYDQLRKQKKKTGKSATTALGDKQRKANESKGTR 421
S S P + + + + +T + + +RK R
Sbjct: 680 RSRSRTPARRGRSRSRTPRRGRSRSRSLVRRGRSHSRTPQRRGRSGSSSERKNKSRTSQR 739
Query: 422 ESWDSAKKLPPVQESQSERLQAAGADSAGPKTVPSHVFSELWDLSEAWMQANYDPLSDSD 481
S ++ S R ++ + + K+ S + L S Q + P S
Sbjct: 740 RSRSNSSPEMKKSRISSRRSRSLSSPRSKAKSRLS-LRRSLSGSSPCPKQKSQTPPRRSR 798
Query: 482 SMTSQAKPEALSSPKFREEAAFPGRRVNAKMP 513
S +SQ K ++ + P+ ++ P + +K P
Sbjct: 799 SGSSQPKAKSRTPPRRSRSSSSPPPKQKSKTP 830
Score = 30.4 bits (67), Expect = 6.3
Identities = 24/67 (35%), Positives = 32/67 (47%), Gaps = 1/67 (1%)
Query: 671 EIKPASKPAGSSHTPSSQSSSGGGRDSSSSILRWLPEKRANPCLSSSNEHAAPA-AKTRK 729
E PA + SS + SS SSS SSSS ++ SSS+ ++P+ AK
Sbjct: 2597 EPTPAKRKRRSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSPSPAKPGP 2656
Query: 730 QAAKKVA 736
QA K A
Sbjct: 2657 QALPKPA 2663
>gi|158854042 hypothetical protein LOC222183 [Homo sapiens]
Length = 653
Score = 46.6 bits (109), Expect = 9e-05
Identities = 65/300 (21%), Positives = 102/300 (34%), Gaps = 37/300 (12%)
Query: 49 IRKTVKRLRKHQHVGDFA--------RDLAARWKKLVLVDRNTRPGPQDPEESASRQRFG 100
+RK K ++KH+ + R +++ K+ RP + P + R G
Sbjct: 199 LRKKKKSVKKHRRDRSDSGSRRKRRHRSRSSKCKRKEKNKEKKRPHTESPGRRSHRHSSG 258
Query: 101 EALQDQEKAWGFPENATAPRSPSHSPEHRRTARRTPPGQQRPHPRSHS--REPRAERKCP 158
+ + + + SP H E R+T + G + P P S P+
Sbjct: 259 SSHSPSLSSHYSDSRSPSRLSPKHRDEGRKTGSQRSSGSRSPSPSGGSGWGSPQRNGGSG 318
Query: 159 RIAPADSGRYRASPTRTAPLRMPEGPEPAAPGKQPGRGHTHAAQG----GPLLCPGCQGQ 214
+ + A GR + +P P P P K T A+G P P QG+
Sbjct: 319 QRSGAHGGR---PGSAHSPPDKPSSPSPRVRDKAAAAAPTPPARGKESPSPRSAPSSQGR 375
Query: 215 PQGKAVVSHSKGHKSSRQEKRPLCAQGDWHSPTLIREKSCGACLREETPRMPSWASARDR 274
G+A + G + R+ +R R +S + R R P A R
Sbjct: 376 -GGRA--AGGAGRRRRRRRRRR-------------RSRSSASAPRRRGRRRPRPAPPRGS 419
Query: 275 QPSDFKTDKEGGQAGSGQRVPALEEAPDSHQKRPQHSHSNKKRPSL---DGRDPGNGTHG 331
S + +GSG+ P P S + H K+RP P G HG
Sbjct: 420 SRS-LSRARSSSDSGSGRGAPGPGPEPGSERGHGGHGKRAKERPPRARPASTSPSPGAHG 478
Score = 37.4 bits (85), Expect = 0.052
Identities = 54/260 (20%), Positives = 84/260 (32%), Gaps = 27/260 (10%)
Query: 84 RPGPQDPEESASRQRFGEALQDQEKAWGFPENATAPRSPSHSPEHRRTARRTPP----GQ 139
RP P P S+ + D G P P S H + A+ PP
Sbjct: 410 RPRPAPPRGSSRSLSRARSSSDSGSGRGAPGPGPEPGSERGHGGHGKRAKERPPRARPAS 469
Query: 140 QRPHPRSHSREPRAERKCPRIAPADSGRYRASPTRTAPLRMPEGPEPAAPGKQPGRGHTH 199
P P +H R E K +P R +S R P + K+P H+
Sbjct: 470 TSPSPGAHGRRGGPEGKSSSRSPGPHPRSWSSS------RSPSKSRSRSAEKRP---HSP 520
Query: 200 AAQGGPLLCPGCQGQPQGKAVVSHSKGHKSSRQEK--RPLCAQGDWHSPTLIREKSCGAC 257
+ P +G+A S ++ ++ R+ + P+ + SP+ + + +
Sbjct: 521 SRSPSPKKPLSRDKDGEGRARHSEAEATRARRRSRSYSPI-RKRRRDSPSFMEPRRITSA 579
Query: 258 LREETP-RMPSWASARDRQPSDFKTDKEGGQAGSGQRVPALEEAPDSHQKRPQHSHSNKK 316
+ P PS +S+ SD+ T G SH SH +
Sbjct: 580 RKRPIPYYRPSPSSSSSCLSSDYSTRSHSRSPSPGH----------SHGSYSSRSHGTRS 629
Query: 317 RPSLDGRDPGNGTHGLSPEE 336
R R P H S E
Sbjct: 630 RTRSPSRTPSPSYHSRSSSE 649
>gi|42542379 serine/arginine repetitive matrix 1 [Homo sapiens]
Length = 904
Score = 46.6 bits (109), Expect = 9e-05
Identities = 85/372 (22%), Positives = 123/372 (33%), Gaps = 42/372 (11%)
Query: 88 QDPEESASRQRFGEALQDQEKAWGFPENATAPRSPSHSPEHRRTARRTPPGQQRPHPRSH 147
Q+ S +Q + +D+E+ E RSP + RR +R RSH
Sbjct: 138 QEKLASMKKQDEDKDKRDKEEKESSREKRERSRSPRRRKSRSPSPRRRSSPVRRERKRSH 197
Query: 148 SREPRAERKCPRIAPADSGRYRASPTRTAPLRMPEGPEPAAPGKQPGRGHTHAAQGGPLL 207
SR PR K +PA + + PE PEP+ K+P + L
Sbjct: 198 SRSPRHRTKSRSPSPAPEKKEKT----------PELPEPSVKVKEPSVQEA-TSTSDILK 246
Query: 208 CPGCQGQPQGKAVVSHSKGHKSSRQEKRPLCAQGDWHSPTLIREKSCGACLREETPRMPS 267
P + P+ K K +EK T R +S R PS
Sbjct: 247 VPKPEPIPEPKEPSPEKNSKKEKEKEK------------TRPRSRSRSKSRSRTRSRSPS 294
Query: 268 WASARDRQPSDFKTDKEGGQAGSGQRVPALEEAPDSHQKRPQHSHSNKKRPSLDGRDPGN 327
R R S ++ + S +R P+ + P H + P R
Sbjct: 295 HTRPRRRHRSRSRS-YSPRRRPSPRRRPSPRRRTPPRRMPPPPRHRRSRSPVRRRRRSSA 353
Query: 328 GTHGLSPEEKEQLSNDRETQEGKPPTAHLDRTS-----VSSLSEVEEVDMAEEFEQPTLS 382
G S S+ ++ PP RTS LS P +
Sbjct: 354 SLSGSS-------SSSSSSRSRSPPKKPPKRTSSPPRKTRRLSPSASPPRRRHRPSPPAT 406
Query: 383 CEKYLTYDQLRKQKKKTGKS-ATTALGDKQRKANESKGT--RESWDSAKKLPPVQESQSE 439
+ +Q +T KS + + G K + KGT RES A K V+ S+SE
Sbjct: 407 PPPKTRHSPTPQQSNRTRKSRVSVSPGRTSGKVTKHKGTEKRESPSPAPKPRKVELSESE 466
Query: 440 RLQA---AGADS 448
+ A ADS
Sbjct: 467 EDKGGKMAAADS 478
Score = 37.7 bits (86), Expect = 0.040
Identities = 73/368 (19%), Positives = 116/368 (31%), Gaps = 39/368 (10%)
Query: 80 DRNTRPGPQDPEESASRQRFGEALQDQEKAWGFPENATAPRSPSHSPEHRRTARRTPPGQ 139
D+ + ++ E + R ++ + P RS S SP HR +R P
Sbjct: 155 DKEEKESSREKRERSRSPRRRKSRSPSPRRRSSPVRRERKRSHSRSPRHRTKSRSPSPAP 214
Query: 140 QRPHPRSHSREPRAERKCPRIAPADSGRYRASPTRTAPLRMPEGPEPAAPGKQPGRGHTH 199
++ EP + K P + A S + P+ P+ P P K+
Sbjct: 215 EKKEKTPELPEPSVKVKEPSVQEATSTSDILKVPKPEPIPEPKEPSPEKNSKKEKEKEKT 274
Query: 200 AAQGGPLLCPGCQGQPQGKA-VVSHSKGHKSSRQEKRPLCAQGDWHSPTLIREKSCGACL 258
P + + + ++ S S H R+ R ++ +SP
Sbjct: 275 R--------PRSRSRSKSRSRTRSRSPSHTRPRRRHR---SRSRSYSPRRRPSPRRRPSP 323
Query: 259 REETP--RMPSWASARDRQPSDFKTDKEGGQAGSGQRVPALEEAPDSHQKRPQHSHSNKK 316
R TP RMP R R S + + + SG S S S K
Sbjct: 324 RRRTPPRRMPPPPRHR-RSRSPVRRRRRSSASLSG----------SSSSSSSSRSRSPPK 372
Query: 317 RPSLDGRDPGNGTHGLSPEEKEQLSNDRETQEGKPP--TAHLDRTSVSSLSEVEEVDMAE 374
+P P T LSP R + PP T H S+ + V ++
Sbjct: 373 KPPKRTSSPPRKTRRLSPSASPPRRRHRPSPPATPPPKTRHSPTPQQSNRTRKSRVSVS- 431
Query: 375 EFEQPTLSCEKYLTYDQLRKQKKKTGKSATTALGDKQRKANESKGTRESWDSAKKLPPVQ 434
P + K + K T K + + K RK S+ + VQ
Sbjct: 432 ----PGRTSGKVTKH-------KGTEKRESPSPAPKPRKVELSESEEDKGGKMAAADSVQ 480
Query: 435 ESQSERLQ 442
+ + R Q
Sbjct: 481 QRRQYRRQ 488
Score = 33.5 bits (75), Expect = 0.75
Identities = 75/329 (22%), Positives = 102/329 (31%), Gaps = 28/329 (8%)
Query: 114 ENATAPRSPSHSPEHRRTARRTPPGQQRPHPRSHSRE--PRAERKCPRIAPADSGRYRAS 171
E+ RS + E R R +P P PR +E PR R+ R R R S
Sbjct: 503 EDERPKRSHVKNGEVGRRRRHSPSRSASPSPRKRQKETSPRGRRR--RSPSPPPTRRRRS 560
Query: 172 PTRTAPLRMPEGPEP----AAPGKQPGRGHTHAAQGGPLLCPGCQGQPQGKAVVSHSKGH 227
P+ P R P P P P R + P + P K +
Sbjct: 561 PSPAPPPRRRRTPTPPPRRRTPSPPPRRRSPSPRRYSPPIQRRYSPSPPPKRRTASPPPP 620
Query: 228 KSSRQEKRPLCAQGDWHSP---------TLIREKSCGACLREETPRMPSWASARDRQPSD 278
R P + HSP T R S + R+ + S AR QP+
Sbjct: 621 PKRRASPSPPPKRRVSHSPPPKQRSSPVTKRRSPSLSSKHRKGSSPSRSTREARSPQPNK 680
Query: 279 FKTDKEGGQA--GSGQRVPALEEAPDSHQKRPQHSHSNKK-RPSLDGRDPGNGTHGLSP- 334
+ +A S P A S Q+R S S + R +P SP
Sbjct: 681 RHSPSPRPRAPQTSSSPPPVRRGASSSPQRRQSPSPSTRPIRRVSRTPEPKKIKKAASPS 740
Query: 335 -------EEKEQLSNDRETQEGKPPTAHLDRTSVSSLSEVEEVDMAEEFEQPTLSCEKYL 387
+S E KPP S S + ++ + PT S
Sbjct: 741 PQSVRRVSSSRSVSGSPEPAAKKPPAPPSPVQSQSPSTNWSPAVPVKKAKSPTPSPSPPR 800
Query: 388 TYDQLRKQKKKTGKSATTALGDKQRKANE 416
DQ KKK K DK+ K ++
Sbjct: 801 NSDQEGGGKKKKKKKDKKHKKDKKHKKHK 829
>gi|224548936 hypothetical protein LOC100170229 [Homo sapiens]
Length = 715
Score = 45.8 bits (107), Expect = 1e-04
Identities = 68/340 (20%), Positives = 123/340 (36%), Gaps = 52/340 (15%)
Query: 51 KTVKRLRKHQHVGDFARDLAARWKKLVLVDRNTRPGPQDPEESASRQRFGEALQDQEKAW 110
+T +R R H + +++ + + +R+ R G P + + R + G + ++ +
Sbjct: 345 RTPRRGRSHNWSRNPSKERSHSHSRSSSKERDHR-GSSSPRKESGRSQSGSPNKQRDHSR 403
Query: 111 GFPENATAPRSPSHSPEHRRTARRTPPGQQRPHPRSHSREPRAERKCPRIAPADSGRYRA 170
N RS S SP R RS SR P R C R R R+
Sbjct: 404 SRSPNKARDRSRSRSPYKARD-------------RSRSRSPNKARDCSRSRSPYKARDRS 450
Query: 171 ---SPTRT---APLRMPEGPEPAAPGKQPGRGHTHAAQGGPLL--------CPGCQGQPQ 216
SP + + R P + + P + H+ G P P + Q +
Sbjct: 451 RSRSPNKARDHSRSRSPNKARDRSRSRSPSKERDHSQLGSPSKERDHRRSRSPSKERQCR 510
Query: 217 GKAVVSHSKGHKSSRQEKRPLCAQGDWHSPTLIREKSCGACLREETPRMPSWASARDRQP 276
S + H+ SR + + SP R++S EE S + +++R
Sbjct: 511 QSRSSSKERDHRRSRSPSKERQRRQS-RSPNKERDRSQSRSPSEEREHRQSRSPSKERDR 569
Query: 277 SDFKT-----DKEGGQAGSGQRVPALEEAPD--SHQKRPQHS-----HSNKKRPSLDGR- 323
+++ ++ ++ S +R + +P+ S RP+ S HS + PS +G
Sbjct: 570 RRWRSPSKERERRQSRSSSEERDHSRSRSPNKQSGYSRPRASSKEKAHSRSRTPSKEGNH 629
Query: 324 ----------DPGNGTHGLSPEEKEQLSNDRETQEGKPPT 353
DP T SP+ K + + + P+
Sbjct: 630 SQSRTSSKESDPSQSTVPRSPDWKRSPTRTSSLSQNRTPS 669
>gi|239749594 PREDICTED: hypothetical protein XP_002347096 [Homo
sapiens]
Length = 201
Score = 45.4 bits (106), Expect = 2e-04
Identities = 52/170 (30%), Positives = 66/170 (38%), Gaps = 24/170 (14%)
Query: 122 PSHSPEHRRTARRTPPGQQRPHPRSHSREPRAERKCPRIAP--ADSGRYRASPTRTAPL- 178
PS +HR TPPG + R + R R+ P A + +P +APL
Sbjct: 28 PSPGLQHRNPLE-TPPGPSKAARRGRGEQVRTHLAPVRVLPNTAAEATAKRAPVPSAPLP 86
Query: 179 --RMPEGPEPAAPGK-----QPGRGHTHAAQGGPLLCPGCQGQPQGKAVVSHSKGHKSSR 231
R P GP+P +P PGRG H L G Q P G+ S
Sbjct: 87 AARSPRGPQPLSPRSSWVRGMPGRG-GHQRPLFSTLGAGFQ-PPLGRGGAGRGGAPASLA 144
Query: 232 QEKRPLCAQGDWHSPTL-IREKSCGACLREETPRMPS----WASARDRQP 276
RP CA +P L RE++ A L TP PS W R R+P
Sbjct: 145 SSARP-CA-----APALPYRERARPAALHWRTPASPSLGSGWFRRRARRP 188
>gi|60097902 filaggrin [Homo sapiens]
Length = 4061
Score = 44.7 bits (104), Expect = 3e-04
Identities = 66/295 (22%), Positives = 109/295 (36%), Gaps = 50/295 (16%)
Query: 91 EESASRQRFGEALQDQEKAWGFPENATAPRSPSHSPEHRRTARRTPPGQQRPHPRSHSRE 150
+ES +R+R G + + G E++ + H ++ G + HPRSH E
Sbjct: 285 QESRTRKRRGSRVSQDRDSEGHSEDSERHSGSASRNHHGSAWEQSRDGSR--HPRSHD-E 341
Query: 151 PRAERKCPRIAPADSGRYRASPTRTAPLRMPEGPEPAAPGKQPGRGHTHAAQGGPLLCPG 210
RA + SG A + ++PG++ G GH +A
Sbjct: 342 DRASHGHSADSSRQSGTRHAETSSRGQTASSHEQARSSPGERHGSGHQQSADSSR---HS 398
Query: 211 CQGQPQGKAVVSHSKGHKSSRQEKRPLCAQGDWHSPTLIREKSCG---ACLREETPRMPS 267
G+ Q + VS +GH+ S + + + HS + G A LR+++ +
Sbjct: 399 ATGRGQASSAVS-DRGHRGSSGSQ---ASDSEGHSENSDTQSVSGHGKAGLRQQSHQ--- 451
Query: 268 WASARDRQPSDFKTDKEGGQAGSGQRVPALEEAPDSHQKRP-------QHSH------SN 314
S R R + + G++GS + E PDS R Q SH S+
Sbjct: 452 -ESTRGR------SGERSGRSGSSLYQVSTHEQPDSAHGRTGTSTGGRQGSHHEQARDSS 504
Query: 315 KKRPSLDGRD-----PGNGTHGLSPEEKEQLSN---------DRETQEGKPPTAH 355
+ S +G+D PG+ G EQ N T +G+ +H
Sbjct: 505 RHSASQEGQDTIRGHPGSSRGGRQGSHHEQSVNRSGHSGSHHSHTTSQGRSDASH 559
Score = 30.8 bits (68), Expect = 4.8
Identities = 29/125 (23%), Positives = 49/125 (39%), Gaps = 8/125 (6%)
Query: 298 EEAPDSHQKRPQHSHSNKKRPSLDGRDPGNGTHGLSPEEKEQLSNDRETQEGKPPTAHLD 357
E P S K +HSH +K D + N + P E+ +N ++G +
Sbjct: 92 ENLPISGHKHRKHSHHDKHE---DNKQEENKENRKRPSSLERRNN----RKGNKGRSKSP 144
Query: 358 RTSVSSLSEVEEVDMAEEFEQPTLSCEKYLTYDQLRKQKKKTGKSATTALGDKQRKANES 417
R + E + PT E+Y + KK+ K+ T LGD +++ +E
Sbjct: 145 RETGGKRHESSSEKKERKGYSPTHREEEY-GKNHHNSSKKEKNKTENTRLGDNRKRLSER 203
Query: 418 KGTRE 422
+E
Sbjct: 204 LEEKE 208
Score = 30.8 bits (68), Expect = 4.8
Identities = 64/317 (20%), Positives = 106/317 (33%), Gaps = 26/317 (8%)
Query: 104 QDQEKAWGFPENATAPRSPSHSPEHRRTARR--TPPGQQ--RPHPRSHSREPRA---ERK 156
+ E A G +T R SH + R ++R + GQ R HP S R + E+
Sbjct: 3394 EQSESAHGRTRTSTGRRQGSHHEQARDSSRHSASQEGQDTIRGHPGSSRRGRQGSHYEQS 3453
Query: 157 CPRIAPADSGR-YRASPTRTAPLRMPEGPEPAA----PGKQPGRGHTHAAQGGPLLCPGC 211
R + S + S R+ R G A+ +Q G G H+
Sbjct: 3454 VDRSGHSGSHHSHTTSQGRSDASRGQSGSRSASRQTRNDEQSGDGSRHSWSHHHEASTQA 3513
Query: 212 QGQPQGKAVVSHSKGHKSSRQEKRPLCAQGDWHSPTLIREKSCGACLREETPRMPSWASA 271
++ S G ++SR + + D + E+ G+ R +
Sbjct: 3514 DSSRHSQSGQGQSAGPRTSRNQGSSVSQDSDSQGHSEDSERWSGSASRNHRGSAQEQSRD 3573
Query: 272 RDRQPSDFKTDKEG-GQAGSGQRVPALEEAPDSHQKRPQHSHSNKKRPSLDGRDPGNGTH 330
R P+ D+ G G + R A +S + SH R H
Sbjct: 3574 GSRHPTSHHEDRAGHGHSAESSRQSGTHHAENSSGGQAASSHE-------QARSSAGERH 3626
Query: 331 GLSPEEKEQLSNDRETQEGKPPTAHLDR----TSVSSLSEVEEVDMAEEFEQPTLSCEKY 386
G ++ S G+ +A D +S S S+ E +E+ + ++S
Sbjct: 3627 GSHHQQSADSSRHSGIGHGQASSAVRDSGHRGSSGSQASDSE--GHSEDSDTQSVSAHGQ 3684
Query: 387 LTYDQLRKQKKKTGKSA 403
Q Q+ G+SA
Sbjct: 3685 AGPHQQSHQESTRGRSA 3701
Score = 30.0 bits (66), Expect = 8.3
Identities = 93/463 (20%), Positives = 145/463 (31%), Gaps = 74/463 (15%)
Query: 104 QDQEKAWGFPENATAPRSPSHSPEHRRTAR-----------RTPPGQQRPHPRSHSREPR 152
+ E A G +T R SH + R ++R R PG +R + E
Sbjct: 1125 EQSESAHGRTRTSTGRRQGSHHEQARDSSRHSASQEGQDTIRAHPGSRRGGRQGSHHEQS 1184
Query: 153 AERKCPRIAPADSGRYRASPT---RTAPLRMPEGPEPAA----PGKQPGRGHTHAAQGGP 205
+R SG + + T R+ G A+ KQ G G H+
Sbjct: 1185 VDRS------GHSGSHHSHTTSQGRSDASHGQSGSRSASRQTRKDKQSGDGSRHSGSRHH 1238
Query: 206 LLCPGCQGQPQGKAVVSHSKGHKSSRQEKRPLCAQGDWHSPTLIREKSCGACLREETPRM 265
+ S G ++SR + + D + E+ G+ R
Sbjct: 1239 EAASWADSSRHSQVGQEQSSGSRTSRHQGSSVSQDSDSERHSDDSERLSGSASRNHHGSS 1298
Query: 266 PSWASARDRQPSDFKTDK--EGGQAGS--------------GQRVPALEEAPDS----HQ 305
+ R P + D+ G A S GQ V + E+A S H
Sbjct: 1299 REQSRDGSRHPGFHQEDRASHGHSADSSRQSGTHHTESSSHGQAVSSHEQARSSPGERHG 1358
Query: 306 KRPQ-------HSHSNKKRPSLDGRDPGN-GTHGLSPEEKEQLSNDRETQEGKPPTAHLD 357
R Q HS ++ S RD G+ G+ G E S D +TQ +AH
Sbjct: 1359 SRHQQSADSSRHSGIGHRQASSAVRDSGHRGSSGSQVTNSEGHSEDSDTQS---VSAHGQ 1415
Query: 358 R-TSVSSLSEVEEVDMAEEFEQPTLSCEKYLTYDQLRKQKKKTGKSATTALGDKQRKANE 416
S E E + + +++Q +T S G + +A
Sbjct: 1416 AGPHQQSHKESARGQSGESSGRSRSFLYQVSSHEQSESTHGQTAPSTGGRQGSRHEQARN 1475
Query: 417 SKGTRESWDSAKKLPPVQESQSERLQAAGADSAGPKTVPSHVFSELWDLSEAWMQANYDP 476
S S D + ++ S G + H S + ++ P
Sbjct: 1476 SSRHSASQDG-----------QDTIRGHPGSSRGGRQGSYHEQSVDRSGHSGYHHSHTTP 1524
Query: 477 LSDSDSMTSQAKPEALSSPKFREEAAFPGRRVNAKMPVYSGSR 519
SD+ Q+ P + S EE + G R +SGSR
Sbjct: 1525 QGRSDASHGQSGPRSASRQTRNEEQSGDGSR-------HSGSR 1560
>gi|145199237 transcription elongation factor B polypeptide 3
binding protein 1 [Homo sapiens]
Length = 1221
Score = 44.7 bits (104), Expect = 3e-04
Identities = 94/421 (22%), Positives = 126/421 (29%), Gaps = 114/421 (27%)
Query: 114 ENATAPRSPSHSPEHRRTARRTPPGQQRPHPRSHSREPRAERKCPRIAPADSGRYRASPT 173
+N+ P + P +AR R + + PR R PA + P
Sbjct: 224 DNSRPPTDLEYDPLSNYSARHLSRASSRDERAA--KRPRGSRGSEPYTPAP--KKLCDPF 279
Query: 174 RTAPLRMPEGPEPAA--PGKQPGRGHTHAAQGGPLLCPGCQGQPQGKAVVSHSKGHKSSR 231
+ R + + AA PG +P T A+ P + GQP K + G
Sbjct: 280 GSCDARFSDSEDEAATVPGNEPTTASTPKARADPEI--KATGQPPSKEGLEAEGGGLRET 337
Query: 232 QEKRPLCAQGDWH-------SPTLIREKSCGACLREETPRM-----PSWASARDRQPSDF 279
+E C GD SP ++ G C +E P+ P S +D
Sbjct: 338 KETAVQCDVGDLQPPPAKPASPAQVQSSQDGGCPKEGKPKKKKTGAPPAPSCKDGAQGKD 397
Query: 280 KT--------------DKEGGQAGSGQRVPALEEAPDSHQKRPQHSH----SNKKRPSLD 321
KT DK+G QA S +R E P+ +K+P + S K RP
Sbjct: 398 KTKDKGRGRPVEKPRADKKGPQASSPRRKA---ERPEGTKKKPSSATPVATSGKGRPDRP 454
Query: 322 GRDPG------NGTHGLSPEEKEQLSNDRETQEGKPPTAHLDRTSVSSLSEVEEVDMAEE 375
R P G P QL + + T K P+ L SL E D
Sbjct: 455 ARRPSPTSGDSRPAAGRGPPRPLQLPDRKST---KAPSGKLVERKARSLDEGASQDA--- 508
Query: 376 FEQPTLSCEKYLTYDQLRKQKKKTGKSATTALGDKQRKANESKGTRESWDSAKKLPPVQE 435
P L KK S GD+ G W SA LP +
Sbjct: 509 ---PKL---------------KKRALSHADLFGDESEDEAAGPGVPSVWPSA--LPSLSS 548
Query: 436 SQSERLQAAGADSAGPKTVPSHVFSELWDLSEAWMQANYDPLSDSDSMTSQAKPEALSSP 495
SDSDS +S PEA P
Sbjct: 549 D-----------------------------------------SDSDSDSSLGFPEAQGPP 567
Query: 496 K 496
K
Sbjct: 568 K 568
Score = 30.0 bits (66), Expect = 8.3
Identities = 21/71 (29%), Positives = 33/71 (46%), Gaps = 3/71 (4%)
Query: 667 PENGEIKPASKPAGSSHTPSSQSSSGGGRDSSSSILRWLPEKRANP---CLSSSNEHAAP 723
P+ + P PA SS + SS S+S G D S L + ++P CL NE +
Sbjct: 567 PKRLKASPPPSPAPSSSSSSSSSTSSAGADVDYSALEKEVDFDSDPMEECLRIFNESTSV 626
Query: 724 AAKTRKQAAKK 734
+ R + A++
Sbjct: 627 KTEDRGRLARQ 637
>gi|41281612 zinc finger protein 828 [Homo sapiens]
Length = 812
Score = 44.3 bits (103), Expect = 4e-04
Identities = 64/239 (26%), Positives = 94/239 (39%), Gaps = 44/239 (18%)
Query: 121 SPSHSPEHRRTARRTPPGQQRPHPRSHSREPRAERKCPRIAPADSGRYRASPTRTAPLRM 180
SP+ SPE R++AR T P ++P P S P + P ++P P R AP
Sbjct: 260 SPAASPESRKSARTTSPEPRKPSP---SESPEPWKPFPAVSP--------EPRRPAPAVS 308
Query: 181 PEGPEPAAPGK-QPGRGHTHAAQG-------GPLLCPGCQGQPQGKAVVSHSKG------ 226
P +P PG +P + + A+ G P + PG K + S S G
Sbjct: 309 PGSWKPGPPGSPRPWKSNPSASSGPWKPAKPAPSVSPG-----PWKPIPSVSPGPWKPTP 363
Query: 227 HKSSRQEKRPLCAQGDWHSPTLIRE--KSCGACLREETPRM--PSW-----ASARDRQPS 277
SS K + W SP E KS LR+ P + W S R+P
Sbjct: 364 SVSSASWKSSSVSPSSWKSPPASPESWKSGPPELRKTAPTLSPEHWKAVPPVSPELRKPG 423
Query: 278 DFKTDKEGGQAGSGQ-RVPALEEAPDSHQKRPQHSHSNKKRPSLDGRDPGNGTHGLSPE 335
+ + AGS + R P+ +PD + P ++ SLD + + G SP+
Sbjct: 424 PPLSPEIRSPAGSPELRKPS--GSPDLWKLSPDQRKTSP--ASLDFPESQKSSRGGSPD 478
>gi|7656879 ALL1 fused gene from 5q31 [Homo sapiens]
Length = 1163
Score = 43.5 bits (101), Expect = 7e-04
Identities = 99/454 (21%), Positives = 163/454 (35%), Gaps = 66/454 (14%)
Query: 137 PGQQRPHPRSHSREPRAERKCPRIAPADSGRYRASPTRTAPLRMPEGPEPAAPGKQPGRG 196
PG+ + S R +K P A +DS R RT + P+ E AA ++P G
Sbjct: 529 PGRDSKTIQKGSESGRGRQKSP--AQSDSTTQR----RTVGKKQPKKAEKAA-AEEPRGG 581
Query: 197 HTHAAQGGPLLCPGCQGQPQGKAVVSHSKGHKSSRQEKRPLCAQGDWHSPTLIREKSCGA 256
++ P A S HK++ + R P + +E
Sbjct: 582 LKIESE-----------TPVDLASSMPSSRHKAATKGSR---------KPNIKKESKSSP 621
Query: 257 CLREETPRMPSWASARDRQPSDFKTDKEGGQAGSGQRVPALEEAPDSHQKRPQHSHSNKK 316
E + S + + + +TD + + +P + P K P+ + + K
Sbjct: 622 RPTAEKKKYKSTSKSSQKSREIIETDTSSSDSDESESLPPSSQTP----KYPESNRTPVK 677
Query: 317 RPSLDGRDPGNGTHGLSP-EEKEQLSNDRETQEGKPPTAHLDRTSVSSLS----EVEEVD 371
S++ D SP EEKE LS E + P +D ++ + + E
Sbjct: 678 PSSVEEEDSFFRQRMFSPMEEKELLSPLSEPDDRYPLIVKIDLNLLTRIPGKPYKETEPP 737
Query: 372 MAEEFEQPTLSCEKYLTYDQLRKQKKKTGKSATTALGDKQRKANESKGTR-ESWDSAKKL 430
E+ P EK+ Q + +K + K + +A+ESK + E +SA
Sbjct: 738 KGEKKNVP----EKHTREAQKQASEKVSNKGKRKHKNEDDNRASESKKPKTEDKNSAGHK 793
Query: 431 PPVQESQSERLQAAGAD----------SAGPKTVPSHVFSELWDLSEAWMQANYDPLS-- 478
P S++ A D S PKT + S +N + +
Sbjct: 794 PSSNRESSKQSAAKEKDLLPSPAGPVPSKDPKTEHGSRKRTISQSSSLKSSSNSNKETSG 853
Query: 479 ---DSDSMTSQAKPE---ALSSPKFREEAAFPGRRVNAKMPVYSGSRPACQLQVPTLRQ- 531
+S S + Q K E + SS + +E+A P S+P V R
Sbjct: 854 SSKNSSSTSKQKKTEGKTSSSSKEVKEKAPSSSSNCPPSAPTLDSSKPRRTKLVFDDRNY 913
Query: 532 ------QCAQVLRNNPDALSDVGEVPYWVLEPVL 559
Q A+ L++N DALSD E + L+ V+
Sbjct: 914 SADHYLQEAKKLKHNADALSDRFEKAVYYLDAVV 947
Score = 40.8 bits (94), Expect = 0.005
Identities = 112/579 (19%), Positives = 200/579 (34%), Gaps = 72/579 (12%)
Query: 192 QPGRGHTHAAQGGPLLCPGCQGQPQGKAVV--SHSKGH------KSSRQEKRPLCAQGDW 243
Q G H+ + P G+PQ + + SHS+ H K ++ K P +W
Sbjct: 168 QHGSEHSKSRSSSP-------GKPQAVSSLNSSHSRSHGNDHHSKEHQRSKSPRDPDANW 220
Query: 244 HSPTLIREKSCGACLREETPRMPSWASARDRQPSDFKTDKEGGQAGSGQRVPALEEAPDS 303
SP+ + S + P + S +++ ++P+ + +G ++ E S
Sbjct: 221 DSPSRVPFSSGQHSTQSFPPSLMSKSNSMLQKPTAYVRPMDGQES---------MEPKLS 271
Query: 304 HQKRPQHSHSNKKRPSLDGRDPGNGTHGLSPEEKEQLSNDRETQEGKPPTAHLDRTSVSS 363
+ SH GN L P K L+ + K P+ LD ++
Sbjct: 272 SEHYSSQSH-------------GNSMTELKPSSKAHLT------KLKIPSQPLDASASGD 312
Query: 364 LSEVEEV--DMAEEFEQPTLSCEKYLTYDQLRKQKKKTGKSATTALG-DKQRKANESKGT 420
+S V+E+ +M + P L+ + K T +S + G +Q++ N SK +
Sbjct: 313 VSCVDEILKEMTHSW-PPPLTAIHTPCKTEPSKFPFPTKESQQSNFGTGEQKRYNPSKTS 371
Query: 421 RESWDSAKKLPPVQESQSERLQA-AGADSAGPKTVPSHVFSELWDLSEAWMQANYDPLSD 479
+ ++ S SE D P++ P SE + D S
Sbjct: 372 NGHQSKSMLKDDLKLSSSEDSDGEQDCDKTMPRSTPGSNSEPSHHNSEGADNSRDDSSSH 431
Query: 480 SDSMTSQAKPEALSSPKFREEAAFPGRRVNAKMPVYSGSRPACQLQVPTLRQQCAQVLRN 539
S S +S S EA P + + + PT + Q L
Sbjct: 432 SGSESSSGSDSESESSSSDSEANEPSQSASPEPE-----------PPPTNKWQLDNWLNK 480
Query: 540 -NPDALSDVGEVPYWVLEPVLEGWRPDQLYRRKKDNHALVRETDELRRNHCFQDFKE-EK 597
NP +S V + P +G++ + + +++ E +D K +K
Sbjct: 481 VNPHKVSPASSVDSNI--PSSQGYKKEGREQGTGNSYTDTSGPKETSSATPGRDSKTIQK 538
Query: 598 PQENKTWREQYLRLPDAPEQRLRV---MTTNIRSARGNNPNGREAKMICFKSVAKTPYDT 654
E+ R++ D+ QR V A P G K ++TP D
Sbjct: 539 GSESGRGRQKSPAQSDSTTQRRTVGKKQPKKAEKAAAEEPRGG------LKIESETPVDL 592
Query: 655 SRRQEKSAGDADPENGEIKPASKPAGSSHTPSSQSSSGGGRDSSSSILRWLPEKRANPCL 714
+ S A + K + SS P+++ SS R + E +
Sbjct: 593 ASSMPSSRHKAATKGSRKPNIKKESKSSPRPTAEKKKYKSTSKSSQKSREIIETDTSSSD 652
Query: 715 SSSNEHAAPAAKTRKQAAKKVAPLMAKAIRDYKRRFSRR 753
S +E P+++T K P+ ++ + F +R
Sbjct: 653 SDESESLPPSSQTPKYPESNRTPVKPSSVEEEDSFFRQR 691
>gi|209862789 microtubule associated monoxygenase, calponin and LIM
domain containing 3 isoform 1 [Homo sapiens]
Length = 2002
Score = 43.1 bits (100), Expect = 0.001
Identities = 38/144 (26%), Positives = 56/144 (38%), Gaps = 9/144 (6%)
Query: 80 DRNTRPGPQDPEESASRQRFGEALQDQEKAWGF-PENATAPRSPSHSPEHRRTARRTPPG 138
D P +E Q QE A F P ++ + P P T ++P
Sbjct: 1136 DEEKLPASPKHQERGPSQATSPIRSPQESALLFIPVHSPSTEGPQLPPVPAATQEKSPEE 1195
Query: 139 QQRPHPRSHSREPRAERKCPRIAPADSGRYRASPTRTAPLRMPEGPEPAAPGKQPGRGHT 198
+ P P +P+A+ AP+D SP R+ P+ +PE P +PG +
Sbjct: 1196 RLFPEPLLPKEKPKAD------APSDLKAVH-SPIRSQPVTLPEARTPVSPGSPQPQPPV 1248
Query: 199 HAAQGGPLLCPGC-QGQPQGKAVV 221
A+ P P C Q QP +A V
Sbjct: 1249 AASTPPPSPLPICSQPQPSTEATV 1272
>gi|239740773 PREDICTED: similar to diffuse panbronchiolitis
critical region 1 [Homo sapiens]
Length = 1400
Score = 42.7 bits (99), Expect = 0.001
Identities = 81/400 (20%), Positives = 132/400 (33%), Gaps = 77/400 (19%)
Query: 80 DRNTRPGPQDPEESASRQRF---------GEALQDQEKAWGFPENAT-APRSPSHSPEHR 129
+ NT P P +P E R F E+ + E+ EN T +P P+ + E
Sbjct: 451 NENTTPSPAEPTEHGERTPFANDKTTSSSAESTEHGERTPLANENTTPSPAEPTENRERT 510
Query: 130 RTARRTPPGQQRPHPRSHSREPRAERK--CPRIAPADSGRYRASPTRTAPLRMPEGPEPA 187
TP P + +RE A K + P ++ A+ T P PA
Sbjct: 511 ANENTTP----SPAGPTENRETTANEKTTLSPVEPTENRETTANEKTT--------PSPA 558
Query: 188 APGKQPGRGHTHAAQGGPLLCPGCQGQPQGKAVVSHSKGHKSSRQEKRPLCAQGDWHSPT 247
P + Q P + S + E+ PL + SP
Sbjct: 559 EPTENG------------------QRTPFANEKTTSSSAEPTEHGERTPLANENTTPSPA 600
Query: 248 LIREKSCGACLREETPRMPSWASARDRQPSDFKTDKEGGQAGSGQRVPALEEAPDSHQKR 307
E + TP DR P + + P+L E ++ Q+
Sbjct: 601 EPTENRERTANEKTTPSPAEPTENGDRTP-----------LANEKTTPSLAEPTENGQRT 649
Query: 308 PQHSHSNKKRPSLDGRDPGNGTHGLSPEEKEQLSNDRETQEGKPPTAHLDR-----TSVS 362
P +N+K S + EE+ L+N+ T PT + +R T+ S
Sbjct: 650 P---FANEKTTS-------SSAEPTEHEERTPLANENTTPSPAEPTENRERTANENTTPS 699
Query: 363 SLSEVEEVDMAEEFEQPTLSCEKYLTYDQLRKQKKKTGKSATTALGDKQRKANE--SKGT 420
E +M + E ++ +K + + T G + ANE + +
Sbjct: 700 PAGPTENREMTANEKTTLFPAEPTENRERTANEKTTSSPAEPTENGQRTPFANEKTTSSS 759
Query: 421 RESWDSAKKLPPVQESQSERLQAAGAD-----SAGPKTVP 455
E + ++ P E+ + L AG +A KT P
Sbjct: 760 AEPTEHGERTPLANENTT--LSPAGPTENRERTANEKTTP 797
Score = 41.2 bits (95), Expect = 0.004
Identities = 83/403 (20%), Positives = 137/403 (33%), Gaps = 61/403 (15%)
Query: 78 LVDRNTRPGPQDPEESASRQRFGEAL------QDQEKAWGFPENATAPRSPSHSPEHRRT 131
L + NT P P +P E+ R + + + +P P+ + E
Sbjct: 491 LANENTTPSPAEPTENRERTANENTTPSPAGPTENRETTANEKTTLSPVEPTENRETTAN 550
Query: 132 ARRTPP-------GQQRPHPR----SHSREPRAERKCPRIAPADSGRYRASPT--RTAPL 178
+ TP GQ+ P S S EP + +A ++ A PT R
Sbjct: 551 EKTTPSPAEPTENGQRTPFANEKTTSSSAEPTEHGERTPLANENTTPSPAEPTENRERTA 610
Query: 179 RMPEGPEPAAPGKQPGRGHTHAAQGGPLLC-PGCQGQ--PQGKAVVSHSKGHKSSRQEKR 235
P PA P + R + P L P GQ P + S + +E+
Sbjct: 611 NEKTTPSPAEPTENGDRTPLANEKTTPSLAEPTENGQRTPFANEKTTSSSAEPTEHEERT 670
Query: 236 PLCAQGDWHS---PTLIREKSCG---------------ACLREETPRMPSWASA-RDRQP 276
PL + S PT RE++ E+T P+ + R+R
Sbjct: 671 PLANENTTPSPAEPTENRERTANENTTPSPAGPTENREMTANEKTTLFPAEPTENRERTA 730
Query: 277 SDFKTDKEGGQAGSGQRVPALEEAPDSHQKRP-QHSHSNKKRPSLDGRDPGNGTHGLSPE 335
++ T +GQR P E S P +H P T E
Sbjct: 731 NEKTTSSPAEPTENGQRTPFANEKTTSSSAEPTEHGERTPLANENTTLSPAGPT-----E 785
Query: 336 EKEQLSNDRETQEGKPPTAHLDRTSVSSLSEVEEVDMAEEFEQPTLSCEKYLTYDQLRKQ 395
+E+ +N++ T PT + +RT+ + + QPT + ++ L +
Sbjct: 786 NRERTANEKTTPFPAEPTENRERTANENTTPSP--------AQPTENGDR----TPLANE 833
Query: 396 KKKTGKSATTALGDKQRKANE--SKGTRESWDSAKKLPPVQES 436
K + T G + ANE + + E + A++ P E+
Sbjct: 834 KTTPSLAEPTENGKRTPFANEKTTSSSAEPTEHAERTPLANEN 876
Score = 31.2 bits (69), Expect = 3.7
Identities = 40/169 (23%), Positives = 68/169 (40%), Gaps = 17/169 (10%)
Query: 290 SGQRVPALEEAPDSHQKRPQHSHSNKKRPSLDGRDP-GNG---THGLSPEEKE--QLSND 343
SGQR P L ++ + H+ Q H N R S P GN H S + E S +
Sbjct: 129 SGQRPPELPKSTEIHE---QKRHCNTTRHSKPTDKPTGNSKTIDHKSSTDNHEAPPTSEE 185
Query: 344 RETQEGKPPTAHLDRT-----SVSSLSEVEEVDMAEEFEQPTLSCEKYLT-YDQLRKQKK 397
+ +GK P R+ S ++ E + ++C K T + ++
Sbjct: 186 NSSNQGKDPMIRNQRSVDPADSTTTHKESAGKKHITPAPKSKINCRKSTTGKSTVTRKSD 245
Query: 398 KTGKSATTALGDKQRKANESKGTRESWDSAKKLPPVQESQS--ERLQAA 444
KTG+ ++ + + S T S+ ++ Q+S S E++ AA
Sbjct: 246 KTGRPLEKSMSTLDKTSTSSHKTTTSFHNSGNSQTKQKSTSFPEKITAA 294
>gi|169218320 PREDICTED: similar to BCL2-associated transcription
factor 1 isoform 2 [Homo sapiens]
Length = 869
Score = 42.4 bits (98), Expect = 0.002
Identities = 51/222 (22%), Positives = 73/222 (32%), Gaps = 29/222 (13%)
Query: 120 RSPSHSPEHRRTARRTPPGQQRPHPRSHSREPRAERKCPRIAPADSGRYRASPTRTAPLR 179
R S SP R+ R+P + RS SR R+ R +P S +SP +P+
Sbjct: 97 RRHSRSPRRGRSRSRSPKRRSVSSQRSRSRSRRSYRSSR--SPRSSSSRSSSPYSKSPVS 154
Query: 180 MPEGPEPAAPGKQPGRGHTHAAQGGPLLCPGCQGQPQGKAVVSHSKGHKSSRQEKRPLCA 239
G + KQ + + PL + Q + K H K +
Sbjct: 155 KRRGSQE----KQTKKAEGEPQEESPL---KSKSQEEPKDTFEHDPSESIDEFNKSSATS 207
Query: 240 QGDWHSPTLIREKSCGACLREETPRMPSWASARDRQPSDFKTDKEGGQAGSGQRVPALEE 299
W G + +PR P S PS Q+ S P L
Sbjct: 208 GDIWP----------GLSAYDNSPRSPHSPSPIATPPS---------QSSSCSDAPMLST 248
Query: 300 APDSHQKRPQHSHSNKKRPSLDGR-DPGNGTHGLSPEEKEQL 340
+ QHSHS + P G GNG+ SP + +
Sbjct: 249 VHSAKNTPSQHSHSIQHSPERSGSGSVGNGSSRYSPSQNSPI 290
>gi|188536004 zinc finger protein 469 [Homo sapiens]
Length = 3925
Score = 42.4 bits (98), Expect = 0.002
Identities = 31/120 (25%), Positives = 55/120 (45%), Gaps = 9/120 (7%)
Query: 86 GPQDPEESASRQRFGEALQD--QEKAWGFPENATAPRSPSHSPEHRRTARRTPPGQQRPH 143
GP++ ES+++++ G+ E F +AP P +P + T R P + +P+
Sbjct: 3778 GPKEKGESSTKRKKGQVPGPARSESVGSFGRAPSAPDKPPRTPRKQATPSRVLPTKPKPN 3837
Query: 144 PRSHSREPRAERKCPRIAPADSGRY----RASPTRTAPLRMPEGPEPAAPGKQPGRGHTH 199
++ R P +E++ + P + R +A P + PL P A G +P HTH
Sbjct: 3838 SQNKPRPPPSEQR--KAEPGHTQRKDRLGKAFP-QGRPLLRPPKRGTAVHGAEPAEPHTH 3894
Score = 42.0 bits (97), Expect = 0.002
Identities = 137/633 (21%), Positives = 217/633 (34%), Gaps = 98/633 (15%)
Query: 106 QEKAWGFPENATAPR---SPSHSPEHRRTA-RRTPPGQQRPHPRSHSREPRAERKCPRIA 161
+EK W P AT+P + S S R T TP G E + R
Sbjct: 2230 KEKLWESPGRATSPPLAGAVSPSVAVRATGLSSTPTGD--------------EAQAGRGL 2275
Query: 162 PADSGRYRASPTRTAPLRMPEGPEPAAPGKQPGRGHT--HAAQGGPLLCPGCQGQ-PQGK 218
P + R +P T P RMP G +P GH A P P QG P
Sbjct: 2276 PGPDPQSRGAPPHTNPDRMPRGHSSYSPSNTARLGHREGQAVTAVPTEPPTLQGAGPDSP 2335
Query: 219 AVVSHSKGHKSSRQEKRPLCAQGDWHSPTLIREKSCGACLREETPRMPSWASARDRQPSD 278
A + G SS++ + P + T + +C T +A SD
Sbjct: 2336 ACLEGEMG-TSSKEPEDPGTPETGRSGATKMPRVTC-----PSTGLGLGRTTAPSSTASD 2389
Query: 279 FKTDKEGGQAGSGQRVPALEEAPDSHQKRPQHSHSNKKRPSL--DGRDPGNGTHG----- 331
F++D + + P + P Q Q S KK+P+ +G+ G HG
Sbjct: 2390 FQSDSPQSHRNASHQTP--QGDPLGPQDLKQRSRGYKKKPASTENGQWKGQAPHGPVTCE 2447
Query: 332 ---LSPEEKEQLSNDRETQEGKPPTAHLDRTSVSSLSEVEEVDMAEEFEQPTLSCEKYLT 388
S LS + + P A + + + ++ +A++ + P
Sbjct: 2448 VCAASFRSGPGLSRHKARKHRPHPGAPAEPSPAALPAQQPLEPLAQKCQPPR-------- 2499
Query: 389 YDQLRKQKKKTGKSATTALGDKQRKANESKGTRESWDSAKKLPPVQESQSERLQAAGADS 448
+K + +GK + N S+G S PP + E L+A G+
Sbjct: 2500 ----KKSHRVSGK----------ERPNHSRGD----PSHVTQPPPAQGSKEVLRAPGSPH 2541
Query: 449 AGPKTVPSHVFSELWDLSEAWMQANYDPLSDSDSMTSQAKPEALSSPKFREEAAFPG--- 505
+ PS E+ D+ + D + + QA E ++R E
Sbjct: 2542 SQQLHPPSPTEHEV-DVKTPASKPRPDQAREDELHPKQA--EKREGRRWRREPTVDSPSH 2598
Query: 506 --RRVNAKMPVYSGSRPACQLQVPTLRQQCAQVLRNNPD-ALSDVGEVPYWVLE----PV 558
+ N K G R + +P + + P A++ P L P
Sbjct: 2599 SEGKSNKKRGKLRGRRLREESILPVSADVISDGRGSRPSPAMASYAASPSHCLSVEGGPE 2658
Query: 559 LEGWRPDQLYRRKKDNHALVRETDELRRNHCFQDFKEEKPQENK---TWREQYLRLPDAP 615
+G +P +L ETD+ C + +KP ++ R L + P
Sbjct: 2659 ADGEQPPRLATLGPGVMEGAAETDQ--EALCAGETGAQKPPGDRMLCPGRMDGAALGEQP 2716
Query: 616 EQRLRVMTTNIRSARGN-NPNGREAKMICFKSVAKTPYDTSRRQEKSAGDADPENGEIKP 674
+ SARG P +A +C +S ++ D+SR +S EN P
Sbjct: 2717 TGQKGA------SARGFWGPRETKALGVCKESGSEPAEDSSRAHSRSEEGVWEEN---TP 2767
Query: 675 ASKPAGSSHTPSSQSSSGGGRDSSSSILRWLPE 707
P G T SS + S ++SS L+ LP+
Sbjct: 2768 PLGPLGFPETSSSPADS-----TTSSCLQGLPD 2795
>gi|117938254 BCL2-associated transcription factor 1 isoform 3 [Homo
sapiens]
Length = 747
Score = 42.4 bits (98), Expect = 0.002
Identities = 51/222 (22%), Positives = 73/222 (32%), Gaps = 29/222 (13%)
Query: 120 RSPSHSPEHRRTARRTPPGQQRPHPRSHSREPRAERKCPRIAPADSGRYRASPTRTAPLR 179
R S SP R+ R+P + RS SR R+ R +P S +SP +P+
Sbjct: 99 RRHSRSPRRGRSRSRSPKRRSVSSQRSRSRSRRSYRSSR--SPRSSSSRSSSPYSKSPVS 156
Query: 180 MPEGPEPAAPGKQPGRGHTHAAQGGPLLCPGCQGQPQGKAVVSHSKGHKSSRQEKRPLCA 239
G + KQ + + PL + Q + K H K +
Sbjct: 157 KRRGSQE----KQTKKAEGEPQEESPL---KSKSQEEPKDTFEHDPSESIDEFNKSSATS 209
Query: 240 QGDWHSPTLIREKSCGACLREETPRMPSWASARDRQPSDFKTDKEGGQAGSGQRVPALEE 299
W G + +PR P S PS Q+ S P L
Sbjct: 210 GDIWP----------GLSAYDNSPRSPHSPSPIATPPS---------QSSSCSDAPMLST 250
Query: 300 APDSHQKRPQHSHSNKKRPSLDGR-DPGNGTHGLSPEEKEQL 340
+ QHSHS + P G GNG+ SP + +
Sbjct: 251 VHSAKNTPSQHSHSIQHSPERSGSGSVGNGSSRYSPSQNSPI 292
>gi|117938251 BCL2-associated transcription factor 1 isoform 2 [Homo
sapiens]
Length = 869
Score = 42.4 bits (98), Expect = 0.002
Identities = 51/222 (22%), Positives = 73/222 (32%), Gaps = 29/222 (13%)
Query: 120 RSPSHSPEHRRTARRTPPGQQRPHPRSHSREPRAERKCPRIAPADSGRYRASPTRTAPLR 179
R S SP R+ R+P + RS SR R+ R +P S +SP +P+
Sbjct: 97 RRHSRSPRRGRSRSRSPKRRSVSSQRSRSRSRRSYRSSR--SPRSSSSRSSSPYSKSPVS 154
Query: 180 MPEGPEPAAPGKQPGRGHTHAAQGGPLLCPGCQGQPQGKAVVSHSKGHKSSRQEKRPLCA 239
G + KQ + + PL + Q + K H K +
Sbjct: 155 KRRGSQE----KQTKKAEGEPQEESPL---KSKSQEEPKDTFEHDPSESIDEFNKSSATS 207
Query: 240 QGDWHSPTLIREKSCGACLREETPRMPSWASARDRQPSDFKTDKEGGQAGSGQRVPALEE 299
W G + +PR P S PS Q+ S P L
Sbjct: 208 GDIWP----------GLSAYDNSPRSPHSPSPIATPPS---------QSSSCSDAPMLST 248
Query: 300 APDSHQKRPQHSHSNKKRPSLDGR-DPGNGTHGLSPEEKEQL 340
+ QHSHS + P G GNG+ SP + +
Sbjct: 249 VHSAKNTPSQHSHSIQHSPERSGSGSVGNGSSRYSPSQNSPI 290
>gi|7661958 BCL2-associated transcription factor 1 isoform 1 [Homo
sapiens]
Length = 920
Score = 42.4 bits (98), Expect = 0.002
Identities = 51/222 (22%), Positives = 73/222 (32%), Gaps = 29/222 (13%)
Query: 120 RSPSHSPEHRRTARRTPPGQQRPHPRSHSREPRAERKCPRIAPADSGRYRASPTRTAPLR 179
R S SP R+ R+P + RS SR R+ R +P S +SP +P+
Sbjct: 99 RRHSRSPRRGRSRSRSPKRRSVSSQRSRSRSRRSYRSSR--SPRSSSSRSSSPYSKSPVS 156
Query: 180 MPEGPEPAAPGKQPGRGHTHAAQGGPLLCPGCQGQPQGKAVVSHSKGHKSSRQEKRPLCA 239
G + KQ + + PL + Q + K H K +
Sbjct: 157 KRRGSQE----KQTKKAEGEPQEESPL---KSKSQEEPKDTFEHDPSESIDEFNKSSATS 209
Query: 240 QGDWHSPTLIREKSCGACLREETPRMPSWASARDRQPSDFKTDKEGGQAGSGQRVPALEE 299
W G + +PR P S PS Q+ S P L
Sbjct: 210 GDIWP----------GLSAYDNSPRSPHSPSPIATPPS---------QSSSCSDAPMLST 250
Query: 300 APDSHQKRPQHSHSNKKRPSLDGR-DPGNGTHGLSPEEKEQL 340
+ QHSHS + P G GNG+ SP + +
Sbjct: 251 VHSAKNTPSQHSHSIQHSPERSGSGSVGNGSSRYSPSQNSPI 292
>gi|239756568 PREDICTED: similar to BCL2-associated transcription
factor 1 [Homo sapiens]
Length = 869
Score = 42.0 bits (97), Expect = 0.002
Identities = 51/222 (22%), Positives = 72/222 (32%), Gaps = 29/222 (13%)
Query: 120 RSPSHSPEHRRTARRTPPGQQRPHPRSHSREPRAERKCPRIAPADSGRYRASPTRTAPLR 179
R S SP R+ R+P + RS SR R+ R +P S +SP +P+
Sbjct: 97 RRHSRSPRRGRSRSRSPKRRSVSSQRSRSRSRRSYRSSR--SPRSSSSRSSSPYSKSPVS 154
Query: 180 MPEGPEPAAPGKQPGRGHTHAAQGGPLLCPGCQGQPQGKAVVSHSKGHKSSRQEKRPLCA 239
G + KQ + + PL + Q + K H K
Sbjct: 155 KRRGSQE----KQTKKAEGELQEESPL---KSKSQEEPKDTFEHDSSESIDEFNKSSATC 207
Query: 240 QGDWHSPTLIREKSCGACLREETPRMPSWASARDRQPSDFKTDKEGGQAGSGQRVPALEE 299
W G + +PR P S PS Q+ S P L
Sbjct: 208 GDIWP----------GLSAYDXSPRSPHSPSPIATPPS---------QSSSCSDAPMLST 248
Query: 300 APDSHQKRPQHSHSNKKRPSLDGR-DPGNGTHGLSPEEKEQL 340
+ QHSHS + P G GNG+ SP + +
Sbjct: 249 VHSAKNTPSQHSHSIQHSPERSGSGSVGNGSSRYSPSQNSPI 290
>gi|66392157 RGD motif, leucine rich repeats, tropomodulin domain and
proline-rich containing [Homo sapiens]
Length = 1435
Score = 42.0 bits (97), Expect = 0.002
Identities = 48/167 (28%), Positives = 64/167 (38%), Gaps = 40/167 (23%)
Query: 77 VLVDRNTRPGP--QDPEESASRQRFGEALQDQ--EKAWGFPENATAPRSPSHSPEHRRTA 132
V D + RPGP Q PE SA+ + G+ L + + WG ++ P SP SP RT+
Sbjct: 1269 VSADPSCRPGPGSQGPE-SATWKTLGQQLNAELRSRGWG-QQDGPGPPSPGQSPSPCRTS 1326
Query: 133 R---------------RTPPGQQRPHPRSHSREPRAERKCPRIAPADSG-RYRASPT--R 174
R GQ RP P S R + + APA+ R + SP R
Sbjct: 1327 PSPDSLGLPEDPCLGPRNEDGQLRPRPLSAGRRAVSVHEDQLQAPAERPLRLQRSPVLKR 1386
Query: 175 TAPLRMPEGP----------------EPAAPGKQPGRGHTHAAQGGP 205
L P P EP++P + P T GGP
Sbjct: 1387 RPKLEAPPSPSLGSGLGTEPLPPQPTEPSSPERSPPSPATDQRGGGP 1433
>gi|238624188 diffuse panbronchiolitis critical region 1 protein
[Homo sapiens]
Length = 1393
Score = 41.6 bits (96), Expect = 0.003
Identities = 74/376 (19%), Positives = 123/376 (32%), Gaps = 70/376 (18%)
Query: 80 DRNTRPGPQDPEESASRQRF---------GEALQDQEKAWGFPENAT-APRSPSHSPEHR 129
+ NT P P +P E R F E+ + E+ EN T +P P+ + E
Sbjct: 389 NENTTPSPAEPTEHGERTPFANDKTTSSSAESTEHGERTPLANENTTPSPAEPTENRERT 448
Query: 130 RTARRTPPGQQRPHPRSHSREPRAERK--CPRIAPADSGRYRASPTRTAPLRMPEGPEPA 187
TP P + +RE A K + P ++ A+ T P PA
Sbjct: 449 ANENTTP----SPAGPTENRETTANEKTTLSPVEPTENRETTANEKTT--------PSPA 496
Query: 188 APGKQPGRGHTHAAQGGPLLCPGCQGQPQGKAVVSHSKGHKSSRQEKRPLCAQGDWHSPT 247
P + Q P + S + E+ PL + SP
Sbjct: 497 EPTENG------------------QRTPFANEKTTSSSAEPTEHGERTPLANENTTPSPA 538
Query: 248 LIREKSCGACLREETPRMPSWASARDRQPSDFKTDKEGGQAGSGQRVPALEEAPDSHQKR 307
E + TP DR P + + P+L E ++ Q+
Sbjct: 539 EPTENRERTANEKTTPSPAEPTENGDRTP-----------LANEKTTPSLAEPTENGQRT 587
Query: 308 PQHSHSNKKRPSLDGRDPGNGTHGLSPEEKEQLSNDRETQEGKPPTAHLDR-----TSVS 362
P +N+K S + EE+ L+N+ T PT + +R T+ S
Sbjct: 588 P---FANEKTTS-------SSAEPTEHEERTPLANENTTPSPAEPTENRERTANENTTPS 637
Query: 363 SLSEVEEVDMAEEFEQPTLSCEKYLTYDQLRKQKKKTGKSATTALGDKQRKANE--SKGT 420
E +M + E ++ +K + + T G + ANE + +
Sbjct: 638 PAGPTENREMTANEKTTLFPAEPTENRERTANEKTTSSPAEPTENGQRTPFANEKTTSSS 697
Query: 421 RESWDSAKKLPPVQES 436
E + ++ P E+
Sbjct: 698 AEPTEHGERTPLANEN 713
Score = 39.7 bits (91), Expect = 0.010
Identities = 81/389 (20%), Positives = 132/389 (33%), Gaps = 56/389 (14%)
Query: 78 LVDRNTRPGPQDPEESASRQRFGEALQ------DQEKAWGFPENATAPRSPSHSPEHRRT 131
L + NT P P +P E+ R + + + +P P+ + E
Sbjct: 429 LANENTTPSPAEPTENRERTANENTTPSPAGPTENRETTANEKTTLSPVEPTENRETTAN 488
Query: 132 ARRTPP-------GQQRPHPR----SHSREPRAERKCPRIAPADSGRYRASPTRTAPLRM 180
+ TP GQ+ P S S EP + +A ++ A PT
Sbjct: 489 EKTTPSPAEPTENGQRTPFANEKTTSSSAEPTEHGERTPLANENTTPSPAEPTENRERTA 548
Query: 181 PEG--PEPAAPGKQPGRGHTHAAQGGPLLC-PGCQGQ--PQGKAVVSHSKGHKSSRQEKR 235
E P PA P + R + P L P GQ P + S + +E+
Sbjct: 549 NEKTTPSPAEPTENGDRTPLANEKTTPSLAEPTENGQRTPFANEKTTSSSAEPTEHEERT 608
Query: 236 PLCAQGDWHSPTLIREKSCGACLREETPRMPSWASARDRQPSDFKTDKEGGQAGSGQRVP 295
PL + SP E RE T A + E + + ++
Sbjct: 609 PLANENTTPSPAEPTEN------RERT--------ANENTTPSPAGPTENREMTANEKTT 654
Query: 296 ALEEAPDSHQKRPQHSHSNKKRPSLDGRDPGNGTHGLSPEEKEQLSNDRETQEGKPPTAH 355
P +++R +N+K S NG ++ +N++ T PT H
Sbjct: 655 LFPAEPTENRERT----ANEKTTSSPAEPTENG-------QRTPFANEKTTSSSAEPTEH 703
Query: 356 LDRTSVSS----LSEVEEVDMAEEF-EQPTLSCEKYLTYDQLRKQKKKTGKSAT--TALG 408
+RT +++ LS E + E + T T ++ R + T S T G
Sbjct: 704 GERTPLANENTTLSPAEPTENRERTANEKTTPFPAEPTENRERTANENTTPSPAQPTENG 763
Query: 409 DKQRKANE--SKGTRESWDSAKKLPPVQE 435
D+ ANE + E ++ K+ P E
Sbjct: 764 DRTPLANEKTTPSLAEPTENGKRTPFANE 792
Score = 37.0 bits (84), Expect = 0.068
Identities = 80/361 (22%), Positives = 119/361 (32%), Gaps = 59/361 (16%)
Query: 80 DRNTRPGPQDPEESASRQRFGEALQDQEKAWGFPENATAP----RSPSHSPEHRRTARRT 135
+ NT P P P E+ R A P ++ S S E A RT
Sbjct: 749 NENTTPSPAQPTENGDRTPLANEKTTPSLAEPTENGKRTPFANEKTTSSSAEPTEHAERT 808
Query: 136 PPGQQRPHPRSHSREPRAERKCPRIAPADSGRYRASPT--RTAPLRMPEGPEPAAPGKQP 193
P + + S EP R+ R A + ++ A PT R + P PA +P
Sbjct: 809 PLANE--NTTSSPAEPTENRE--RTANEKTTQFPAEPTENRESTANEKTTPFPA----EP 860
Query: 194 GRGHTHAAQGGPLLCPGCQGQPQGKAVVSHSKGHKSSRQEKRPLCAQGDWHSPTLIREKS 253
A L P + +E PL + SP E
Sbjct: 861 TENREWTANENTTLSPA----------------EPTEHEEMTPLANEKTTLSPAEPTENG 904
Query: 254 CGACLREE--TPRMPSWASARDRQP--SDFKTDKEGGQAGSGQRVPALEEAPDSHQKRPQ 309
E TP +R P ++ T G+R+ A E+A S K +
Sbjct: 905 ERTPFTNEKTTPSSAEPTEHGERTPLANEITTPSRAEPTEHGERI-ANEKATPSPAKPTE 963
Query: 310 HSHS--------NKKRPSLDG-RDP-GNGTHGLSPEEK----EQLSNDRETQEGKPPTAH 355
H + + P+ +G R P N SP E E+ +N++ T PT H
Sbjct: 964 HGETTVNEDTTPSSAEPTENGERTPLANENTTTSPTESTEHGERTANEKTTPSPAEPTEH 1023
Query: 356 LDRTSVSSLSEVEEVDMAEEFEQPTLSCEKYLTYDQLRKQKKKTGKSATTALGDKQRKAN 415
+RT ++ + E E+ T S + T ++ T G+K AN
Sbjct: 1024 GERTPSANEKTIPSPAKPTEHEEMTPSANENTTPSPVK----------PTEHGEKTTLAN 1073
Query: 416 E 416
E
Sbjct: 1074 E 1074
Score = 32.3 bits (72), Expect = 1.7
Identities = 71/373 (19%), Positives = 126/373 (33%), Gaps = 57/373 (15%)
Query: 78 LVDRNTRPGPQDPEESASRQRFGEALQDQEKAWGFPENATAPRSPSHSPEHRRTARRTPP 137
L + T P +P E+ R F T ++ S E RTP
Sbjct: 888 LANEKTTLSPAEPTENGERTPF-----------------TNEKTTPSSAEPTEHGERTPL 930
Query: 138 GQQ-----RPHPRSHSREPRAERKCPRIA-PADSGRYRASPTRTAPLRMPEGPEPAAPGK 191
+ R P H E+ P A P + G + T P EP G+
Sbjct: 931 ANEITTPSRAEPTEHGERIANEKATPSPAKPTEHGETTVNEDTT-----PSSAEPTENGE 985
Query: 192 QPGRGHTHAAQGGPLLCPGCQGQPQGKAVVSHSKGHKSSRQEKRPLCAQGDWHSPTL--I 249
+ PL P S G +++ ++ P A+ H
Sbjct: 986 RT-----------PLANENTTTSP----TESTEHGERTANEKTTPSPAEPTEHGERTPSA 1030
Query: 250 REKSCGACLREETPRMPSWASARDRQPSDFKTDKEGGQAG-SGQRVPALEEAPDSHQKRP 308
EK+ + + + ++ + PS K + G + + +++ E P H +
Sbjct: 1031 NEKTIPSPAKPTEHEEMTPSANENTTPSPVKPTEHGEKTTLANEKITLSPEGPTEHGAKT 1090
Query: 309 QHSHSNKKRPSLDGRDPGNGTHGLSPEEKEQLSNDRETQEGKPPTAHLDRTSVSSLSEVE 368
S + K PSL + +G SP ND+ T T H DR + +++
Sbjct: 1091 T-SANEKITPSL-AKPTEHGERTTSP-------NDKITSSAAESTEHRDRATSANVITPA 1141
Query: 369 EVDMAEEFEQPTLSCEKYLTYDQLRKQKKKTGKSATTALGDKQRKANESKGTRESWDSAK 428
+ + ++ TL+ EK + K + K+ +T + + + ++ +
Sbjct: 1142 PAEPIKHAKRTTLAHEKMTQVTE--KSTEHPEKTTSTTEKTTRTPEKPTLYSEKTICTKG 1199
Query: 429 KLPPVQESQSERL 441
K PV E +E L
Sbjct: 1200 KNTPVPEKPTENL 1212
Score = 31.2 bits (69), Expect = 3.7
Identities = 40/169 (23%), Positives = 68/169 (40%), Gaps = 17/169 (10%)
Query: 290 SGQRVPALEEAPDSHQKRPQHSHSNKKRPSLDGRDP-GNG---THGLSPEEKE--QLSND 343
SGQR P L ++ + H+ Q H N R S P GN H S + E S +
Sbjct: 67 SGQRPPELPKSTEIHE---QKRHCNTTRHSKPTDKPTGNSKTIDHKSSTDNHEAPPTSEE 123
Query: 344 RETQEGKPPTAHLDRT-----SVSSLSEVEEVDMAEEFEQPTLSCEKYLT-YDQLRKQKK 397
+ +GK P R+ S ++ E + ++C K T + ++
Sbjct: 124 NSSNQGKDPMIRNQRSVDPADSTTTHKESAGKKHITPAPKSKINCRKSTTGKSTVTRKSD 183
Query: 398 KTGKSATTALGDKQRKANESKGTRESWDSAKKLPPVQESQS--ERLQAA 444
KTG+ ++ + + S T S+ ++ Q+S S E++ AA
Sbjct: 184 KTGRPLEKSMSTLDKTSTSSHKTTTSFHNSGNSQTKQKSTSFPEKITAA 232
>gi|62362414 c-abl oncogene 1, receptor tyrosine kinase isoform a
[Homo sapiens]
Length = 1130
Score = 41.6 bits (96), Expect = 0.003
Identities = 57/258 (22%), Positives = 101/258 (39%), Gaps = 39/258 (15%)
Query: 67 RDLAARWKKLVLVDRNTRPGPQDPEESASRQRFGEALQDQ-EKAWGFPENATAPRSPSHS 125
RDL + ++ D +T G + + + R+R GE DQ + P ++ +
Sbjct: 738 RDLQSTGRQF---DSSTFGGHKSEKPALPRKRAGENRSDQVTRGTVTPPPRLVKKNEEAA 794
Query: 126 PEHRRTARRTPPGQQRPHPRSHSREPRAERKCPRIAPADSGRYRASPTRTAPLRMPEGPE 185
E + + PG P+ P+ R+ +APA ++ + + L P E
Sbjct: 795 DEVFKDIMESSPGSSPPN-----LTPKPLRRQVTVAPASGLPHKEEAGKGSALGTPAAAE 849
Query: 186 PAAPGKQPGRGHTHAAQGGPLLCPGCQGQPQGKAVVSHSKGHKSSRQEKRPLCAQGDWHS 245
P P + G G PG G +G A S + HK S + S
Sbjct: 850 PVTPTSKAGSG-----------APG--GTSKGPAEESRVRRHKHSSE------------S 884
Query: 246 PTLIREKSCGACLREETPRMPSWASAR-DRQPSDFKTDKEGGQA--GSGQRVPALEEAPD 302
P R+K + L+ P P+ ++ + +PS + + G+A G+ + +L +A +
Sbjct: 885 PG--RDKGKLSRLKPAPPPPPAASAGKAGGKPSQSPSQEAAGEAVLGAKTKATSLVDAVN 942
Query: 303 SHQKRPQHSHSNKKRPSL 320
S +P K+P L
Sbjct: 943 SDAAKPSQPGEGLKKPVL 960
>gi|62362412 c-abl oncogene 1, receptor tyrosine kinase isoform b
[Homo sapiens]
Length = 1149
Score = 41.6 bits (96), Expect = 0.003
Identities = 57/258 (22%), Positives = 101/258 (39%), Gaps = 39/258 (15%)
Query: 67 RDLAARWKKLVLVDRNTRPGPQDPEESASRQRFGEALQDQ-EKAWGFPENATAPRSPSHS 125
RDL + ++ D +T G + + + R+R GE DQ + P ++ +
Sbjct: 757 RDLQSTGRQF---DSSTFGGHKSEKPALPRKRAGENRSDQVTRGTVTPPPRLVKKNEEAA 813
Query: 126 PEHRRTARRTPPGQQRPHPRSHSREPRAERKCPRIAPADSGRYRASPTRTAPLRMPEGPE 185
E + + PG P+ P+ R+ +APA ++ + + L P E
Sbjct: 814 DEVFKDIMESSPGSSPPN-----LTPKPLRRQVTVAPASGLPHKEEAGKGSALGTPAAAE 868
Query: 186 PAAPGKQPGRGHTHAAQGGPLLCPGCQGQPQGKAVVSHSKGHKSSRQEKRPLCAQGDWHS 245
P P + G G PG G +G A S + HK S + S
Sbjct: 869 PVTPTSKAGSG-----------APG--GTSKGPAEESRVRRHKHSSE------------S 903
Query: 246 PTLIREKSCGACLREETPRMPSWASAR-DRQPSDFKTDKEGGQA--GSGQRVPALEEAPD 302
P R+K + L+ P P+ ++ + +PS + + G+A G+ + +L +A +
Sbjct: 904 PG--RDKGKLSRLKPAPPPPPAASAGKAGGKPSQSPSQEAAGEAVLGAKTKATSLVDAVN 961
Query: 303 SHQKRPQHSHSNKKRPSL 320
S +P K+P L
Sbjct: 962 SDAAKPSQPGEGLKKPVL 979
>gi|239754748 PREDICTED: hypothetical protein [Homo sapiens]
Length = 229
Score = 41.6 bits (96), Expect = 0.003
Identities = 30/81 (37%), Positives = 40/81 (49%), Gaps = 7/81 (8%)
Query: 113 PENATAPRSPSHSPEH-RRTARRTPPGQQRPHPRSHSREPRAERKCPRIAPADSGRYRAS 171
P T PRSPS P+ R++RR PP +RP + + R+ C R P SGR+ S
Sbjct: 99 PTLGTQPRSPSTGPDRVPRSSRRLPPESRRPGGPAKTHPARS--ACCR--PRKSGRWPQS 154
Query: 172 PTRTAPLRMPEGPEPAAPGKQ 192
R P + P+P AP Q
Sbjct: 155 TARGLPAK--TRPKPPAPAPQ 173
>gi|154800457 centrosomal protein 68kDa [Homo sapiens]
Length = 757
Score = 41.2 bits (95), Expect = 0.004
Identities = 47/171 (27%), Positives = 66/171 (38%), Gaps = 17/171 (9%)
Query: 84 RPGPQDPEESASRQRFGEALQDQEKAWGFPENATAPRSPSHSPEHRRTARRTPPGQQRPH 143
RPGPQ P+ SR LQD + +P S SP + + PP +
Sbjct: 310 RPGPQLPKHLDSRVPADPVLQD--SGVDLDSFSVSPASTLKSPTN--VSPNCPPAEATAL 365
Query: 144 PRSHSREPRAERKCPRIAPADSGRYRASPTRTAPL-RMP-------EGPEPAAPG-KQPG 194
P S REP ++ R+ G AS ++ A R P E EPA G K
Sbjct: 366 PFSGPREPSLKQWPSRVPQKQGGMGLASWSQLASTPRAPGSRDARWERREPALRGAKDRL 425
Query: 195 RGHTHAAQGGPLLCPGCQGQPQGKAVVSHSKGHKSSRQEKRPLCAQGDWHS 245
H G P L +G P + + ++S+ +RP C + W S
Sbjct: 426 TIGKHLDMGSPQLRTRDRGWPSPRP----EREKRTSQSARRPTCTESRWKS 472
>gi|122937267 lemur tyrosine kinase 3 [Homo sapiens]
Length = 1489
Score = 40.8 bits (94), Expect = 0.005
Identities = 90/392 (22%), Positives = 136/392 (34%), Gaps = 64/392 (16%)
Query: 87 PQDPEESASRQRFGEALQD---QEKAWGFPE------NATAPRSPSHSPEHRRTARRTPP 137
P PE+ +S + +L D A PE A AP+ P P PP
Sbjct: 730 PHPPEDDSSLRAERGSLADLPMAPPASAPPEFLDPLMGAAAPQYPGRGPPPAPPPPPPPP 789
Query: 138 GQQR-----PHPRSHSREPRAERKCPRIAPADSGRYRASPTRTA---------------- 176
P P S P + P P DSG +P
Sbjct: 790 RAPADPAASPDPPSAVASPGSGLSSPGPKPGDSGYETETPFSPEGAFPGGGAAEEEGVPR 849
Query: 177 PLRMPEGPEPAAPGKQPGRGHTHAAQGGPLLCPGCQGQPQGKAVVSHSKGHKSSRQEKRP 236
P PE P+P AP P GPL PG + +P VS + S R++
Sbjct: 850 PRAPPEPPDPGAPRPPP--------DPGPLPLPGPREKPTFVVQVSTEQLLMSLREDV-- 899
Query: 237 LCAQGDWHSPTLIREKSCGACLREETPRMPSWASA-RDRQPSDFKTDKEGGQAGSGQRVP 295
+ L+ EK GA RE PR R++ P +++ G+G++ P
Sbjct: 900 --------TRNLLGEK--GATARETGPRKAGRGPGNREKVPG---LNRDPTVLGNGKQAP 946
Query: 296 ALEEAPDSHQKRPQHSHSNKKRPSLDGRDPGNGTHGLSPEEKEQLSNDRETQEGKPPTAH 355
+L + + +++ P ++ + NG G SPE +E++ + E +
Sbjct: 947 SLSLPVNGVTVL---ENGDQRAPGIEEKAAENGALG-SPEREEKVLENGELTPPRREEKA 1002
Query: 356 LDRTSVSSLSEVEEVDMAEEFEQPTLSCEKYLTYDQLRKQKKKTGKSATTALGDKQRKAN 415
L+ + S E+V + P S +K LR + T R
Sbjct: 1003 LENGELRSPEAGEKV-LVNGGLTPPKSEDKVSENGGLRFPRNTERPPET----GPWRAPG 1057
Query: 416 ESKGTRESWDSAKKL-PPVQESQSERLQAAGA 446
+ T ESW A + P E+ ER A A
Sbjct: 1058 PWEKTPESWGPAPTIGEPAPETSLERAPAPSA 1089
Score = 32.7 bits (73), Expect = 1.3
Identities = 39/143 (27%), Positives = 50/143 (34%), Gaps = 21/143 (14%)
Query: 85 PGPQD--PEESASRQRFGEALQDQEKAWGFPENATAPRSPSHSPEHRRTARRTPPGQQRP 142
PGP + PE GE + E A AP + S R T PG P
Sbjct: 1056 PGPWEKTPESWGPAPTIGEPAPETSL-----ERAPAPSAVVSS----RNGGETAPGPLGP 1106
Query: 143 HPRSHSREPRAERKCPRIAPADSGRYRASPTRTAPLRMPEGPEPAAPGKQPGRG------ 196
P++ + EP ER+ P A + R P G APG PG G
Sbjct: 1107 APKNGTLEPGTERRAPETGGAPRAPGAGRLDLGSGGRAPVG-TGTAPGGGPGSGVDAKAG 1165
Query: 197 ---HTHAAQGGPLLCPGCQGQPQ 216
+T P L P + QP+
Sbjct: 1166 WVDNTRPQPPPPPLPPPPEAQPR 1188
>gi|4504713 insulinoma-associated 1 [Homo sapiens]
Length = 510
Score = 40.8 bits (94), Expect = 0.005
Identities = 53/199 (26%), Positives = 73/199 (36%), Gaps = 29/199 (14%)
Query: 112 FPENATAPRSPSHSPEHRRTARRTPPGQQRPHPRSHSREPRAERKCPRIAPADSGR--YR 169
F A A R P P A PPG+ RP P + + P K P + R +
Sbjct: 173 FSAGAEAARGPGPGPPLPPAAALRPPGK-RPPPPTAAEPPAKAVKAPGAKKPKAIRKLHF 231
Query: 170 ASPTRTAP---LRMPEGPEPAAPGKQPGRGHTHAAQGGPLLCPGCQGQPQGKAVVSHSKG 226
T+P L++ EGP A G+ G A G +C C+ + ++ K
Sbjct: 232 EDEVTTSPVLGLKIKEGPVEAPRGRAGGA----ARPLGEFICQLCKEEYADPFALAQHKC 287
Query: 227 HKSSRQEKR-PLCAQ-----------GDWHSPTLIREKSCGACLREETPRMPSWASARDR 274
+ R E R P CA+ WH P + A R P + A AR+
Sbjct: 288 SRIVRVEYRCPECAKVFSCPANLASHRRWHKP-----RPAPAAARAPEPEAAARAEAREA 342
Query: 275 Q--PSDFKTDKEGGQAGSG 291
SD T GG + SG
Sbjct: 343 PGGGSDRDTPSPGGVSESG 361
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.310 0.126 0.375
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 35,063,840
Number of Sequences: 37866
Number of extensions: 1991624
Number of successful extensions: 10704
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 43
Number of HSP's successfully gapped in prelim test: 638
Number of HSP's that attempted gapping in prelim test: 9370
Number of HSP's gapped (non-prelim): 1887
length of query: 753
length of database: 18,247,518
effective HSP length: 110
effective length of query: 643
effective length of database: 14,082,258
effective search space: 9054891894
effective search space used: 9054891894
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.